LOCUS       DAZUDJ010000001       144703 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.001, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000001 DAZUDJ010000000
VERSION     DAZUDJ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 144703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 144703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..144703
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.001"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(90..365)
                     /locus_tag="ACHY1N_000001"
     CDS             complement(90..365)
                     /locus_tag="ACHY1N_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory phage cox family protein"
                     /protein_id="HFS4042367.1"
                     /translation="MSKQVVSISDAVPYQEFAKLIGKTPAAVRGMIEKGKLPVVEMTD
                     PQSTSGRAGEYWVYLPAWNNGMKMAYESRPKEIREGWLMWLGLGNPS"
     gene            489..788
                     /locus_tag="ACHY1N_000002"
     CDS             489..788
                     /locus_tag="ACHY1N_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4042368.1"
                     /translation="MSTPISEKLALVRESERLNRKQFAEITGVPYSSLTYYESGRTTP
                     PTDVTMKILQHPRFSKYTLWFMTDQVAPEAGQIAPALAHFGQDVTTSQHSDQKIG"
     gene            934..1941
                     /locus_tag="ACHY1N_000003"
     CDS             934..1941
                     /locus_tag="ACHY1N_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4042369.1"
                     /translation="MTIKKLDDGRYEVDIRPAGRNGKRIRRKFDKKSEAVAFEKHTQY
                     NHHDKEWLAKPTDKRHLSELTKVWWDLKGKHEEHGKSNLGKIEIFTRITDDPCAFQIT
                     KALISQYSMTRRGQGIKPASINRDLTCLSGMFTALIDAELFFGEHPFRGMKKLKEQKP
                     ETGYLTQEEITLLLANLDGDNKKIAILCLSTGARWGEAAKLKAENVIQNRVTFVKTKT
                     NKPRTVPISEEVAVMIAGKGYLFPDASYPKFRRTMKDVKPDLPDGQATHALRHSFATH
                     FMINGGSIITLQRILGHSRIEQTMVYAHFAPEYLQDAVSLNPLRGGVDSQSVHTVSTV
                     G"
     gene            complement(2206..2523)
                     /gene="yegR"
                     /locus_tag="ACHY1N_000004"
     CDS             complement(2206..2523)
                     /gene="yegR"
                     /locus_tag="ACHY1N_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310918.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YegR"
                     /protein_id="HFS4042370.1"
                     /translation="MKKIAAISLISIFIMSGCAVHNDETSIGKFGLAYKSNIQRKLDN
                     QYYTEAEASLARGRISGAENIVKNDAAHFCVTQGKKMQIVDLKTEGAGLHGVARLTFK
                     CGE"
     gene            2938..3837
                     /gene="yegS"
                     /locus_tag="ACHY1N_000005"
     CDS             2938..3837
                     /gene="yegS"
                     /locus_tag="ACHY1N_000005"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HFS4042371.1"
                     /translation="MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKG
                     DAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATS
                     VGIPEALDKALKLAIAGNAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALG
                     GVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALIND
                     GLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQ
                     NFHIEILPAALRCRLPPDCPLLR"
     gene            complement(3919..4692)
                     /locus_tag="ACHY1N_000006"
     CDS             complement(3919..4692)
                     /locus_tag="ACHY1N_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4042372.1"
                     /translation="MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLE
                     QKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVI
                     LDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
                     IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNR
                     RGFNQVLPIEKIDIIITDDAVSEVDKLALQKTRVKLITV"
     gene            complement(4798..5838)
                     /gene="gatD"
                     /locus_tag="ACHY1N_000007"
     CDS             complement(4798..5838)
                     /gene="gatD"
                     /locus_tag="ACHY1N_000007"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFS4042373.1"
                     /translation="MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR
                     IFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQ
                     CAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCE
                     NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP
                     QMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKI
                     LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIA
                     RNAMPGKVLLIP"
     gene            complement(5886..7241)
                     /locus_tag="ACHY1N_000008"
     CDS             complement(5886..7241)
                     /locus_tag="ACHY1N_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015577 - galactitol transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015796 - galactitol transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HFS4042374.1"
                     /translation="MFSEVMRYILDLGPTVMLPVVIIIFSKILGMKAGDCFKAGLHIG
                     IGFVGIGLVIGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPI
                     AILVNVAMLLTRMTRVVNVDIWNIWHMTFTGALLHLATGSWMIGMAGVVIHAAFVYKL
                     GDWFARDTRNFFELEGIAIPHGTSAYMGPIAVLVDAIIEKIPGVNRIKFSADDIQRKF
                     GPFGEPVTVGFVMGLIIGILAGYDVKGVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAK
                     QARSRLQAKFGGQEFLIGLDPALLLGHTAVVSASLIFIPLTILIAVCVPGNQVLPFGD
                     LATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQTIGLHTQLAANAGALKAGG
                     MVASMDQGGSPITWLLIQVFSPQNIPGFIIIGAIYLTGIFMTWRRARGFIKQEKVVLA
                     E"
     gene            complement(7245..7529)
                     /gene="gatB"
                     /locus_tag="ACHY1N_000009"
     CDS             complement(7245..7529)
                     /gene="gatB"
                     /locus_tag="ACHY1N_000009"
                     /EC_number="2.7.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HFS4042375.1"
                     /translation="MKRKIIVACGGAVATSTMAAEEIKELCQSHNIPVELIQCRVNEI
                     ETYMDGVHLICTTARGDRSFGDIPLVHGMPFVSGVGIEALQNKILTILQG"
     gene            complement(7560..8012)
                     /gene="gatA"
                     /locus_tag="ACHY1N_000010"
     CDS             complement(7560..8012)
                     /gene="gatA"
                     /locus_tag="ACHY1N_000010"
                     /EC_number="2.7.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HFS4042376.1"
                     /translation="MTNLFVRSGISFVDRSEVLTHIGNEMLAKGVVHDTWPQALIARE
                     AEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTNKVHFQQADDDNDVAVSLVIALI
                     VENPQQQLKLLRCLFGKLQQPDIVETLITLPETQLKEYFTKYVLDSDE"
     gene            complement(8022..9284)
                     /gene="gatZ"
                     /locus_tag="ACHY1N_000011"
     CDS             complement(8022..9284)
                     /gene="gatZ"
                     /locus_tag="ACHY1N_000011"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
                     /protein_id="HFS4042377.1"
                     /translation="MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIE
                     ATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAA
                     MEKSVELVKEYVRAGFSKIHLDASMSCAGDPIPLAPETVAERAAVLCFAAESVATDCQ
                     REQLSYVIGTEVPVPGGEASAIQSVHITHVEDTANTLRTHQKAFIARGLTEALTRVIA
                     IVVQPGVEFDHSNIIHYQPQEAQPLAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFA
                     ILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGF
                     NDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQS
                     GELSAIPHQLIMDKIYDVLRAYRYGCAE"
     gene            complement(9325..10167)
                     /gene="gatY"
                     /locus_tag="ACHY1N_000012"
     CDS             complement(9325..10167)
                     /gene="gatY"
                     /locus_tag="ACHY1N_000012"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HFS4042378.1"
                     /translation="MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAP
                     VIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVM
                     IDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQA
                     REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDI
                     QQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIA
                     DCGC"
     gene            complement(10477..11529)
                     /gene="fbaB"
                     /locus_tag="ACHY1N_000013"
     CDS             complement(10477..11529)
                     /gene="fbaB"
                     /locus_tag="ACHY1N_000013"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HFS4042379.1"
                     /translation="MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQL
                     ANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKITIA"
     gene            11786..13063
                     /gene="yegT"
                     /locus_tag="ACHY1N_000014"
     CDS             11786..13063
                     /gene="yegT"
                     /locus_tag="ACHY1N_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015858 - nucleoside transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease"
                     /protein_id="HFS4042380.1"
                     /translation="MKTTAKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGALLMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQILGYADISPT
                     NIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYPEPVNGLTFNWSGMWTFGAVMIAII
                     AVLFMIFFRESDNEITAIKVDDRDIALTQGEVK"
     gene            13060..14064
                     /gene="yegU"
                     /locus_tag="ACHY1N_000015"
     CDS             13060..14064
                     /gene="yegU"
                     /locus_tag="ACHY1N_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HFS4042381.1"
                     /translation="MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTSMALCLADALLEREGKIDPDLIGRNILDWALRFDAFNKN
                     VLGPTSKIALNAIRDGKPVAELENNGVTNGAAMRVSPLGCLLPARDVDSFIDDVALAS
                     SPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRITTFSASLAAR
                     LEIALKIVRNADGTESASEQLYQVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVNAIDPALKAELDAVNQLDFNRYATALAKYRQQREAV
                     "
     gene            14061..15026
                     /gene="yegV"
                     /locus_tag="ACHY1N_000016"
     CDS             14061..15026
                     /gene="yegV"
                     /locus_tag="ACHY1N_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HFS4042382.1"
                     /translation="MSGARLHTLLPELTSRQPVMVVGAAVIDVIADAYALPWRGCDIE
                     LKQQSVNVGGCALNIAVALKRLGIEAGNALPLGQGVWAEIIRNRMAKEGLISLIDNAE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNRQWLARLTVAPGSLLYFSGYQLASPCGEL
                     LVEWLEELQDVTPFIDFGPRIGDIPDALLPRIMACRPLVSLNRQEAEIAAERFALSAE
                     ITTLGEQWQEKFAAPLIVRLDKEGAWYFSNDASGCIPAFPTQVVDTIGAGDSHAGGVL
                     AGLASGLPLADAVLLGNAVASWVVGHRGGDCAPTREELLLAHKNV"
     gene            complement(15000..15746)
                     /gene="yegW"
                     /locus_tag="ACHY1N_000017"
     CDS             complement(15000..15746)
                     /gene="yegW"
                     /locus_tag="ACHY1N_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4042383.1"
                     /translation="MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHG
                     NILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRSRGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRSQHIYLQRTRSRVSARMPDAEFQSHIQLDSKIPVLVI
                     KQVALDQQQRPIEYSISHCRSDLYVFVCEE"
     gene            complement(15798..16616)
                     /gene="yegX"
                     /locus_tag="ACHY1N_000018"
     CDS             complement(15798..16616)
                     /gene="yegX"
                     /locus_tag="ACHY1N_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HFS4042384.1"
                     /translation="MQLRITSRKKLTSLLCALGLISIVAIYPRQTVNFFYSTAVQITD
                     YIHFYGYRPVKSFAIRIPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKAT
                     EGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVL
                     DVEERGKLSAKELRKRVSQWLKMVEKSTGKKPIIYSGTVFYHTNLAGYFNEYPWWVAH
                     YYQRRPDNDGMAWRFWQYSDRGQVDGINGPVDFNVFNGTVEELQGFVDGIKETP"
     gene            complement(16681..17481)
                     /gene="thiD"
                     /locus_tag="ACHY1N_000019"
     CDS             complement(16681..17481)
                     /gene="thiD"
                     /locus_tag="ACHY1N_000019"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFS4042385.1"
                     /translation="MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQNV
                     VLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAPHARTEQEMLE
                     QGRSLLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTAPRIMTKNTHGTGCTLSAA
                     LAALRPRHTNWADTVQEAKSWLSSALAQADTLEVGHGIGPVHHFHAWW"
     gene            complement(17478..18266)
                     /gene="thiM"
                     /locus_tag="ACHY1N_000020"
     CDS             complement(17478..18266)
                     /gene="thiM"
                     /locus_tag="ACHY1N_000020"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HFS4042386.1"
                     /translation="MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLAL
                     GASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKSSQTPWTLDPVA
                     VGALDYRRHFCHELLSFKPAAIRGNASEIMALAGIANGGRGVDTTDAAANAIPAAQTL
                     ARETGAIVVVTGEVDYVTDGHRAVGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTL
                     ENVASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA"
     regulatory      complement(18301..18397)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(18489..18761)
                     /gene="rcnR"
                     /locus_tag="ACHY1N_000021"
     CDS             complement(18489..18761)
                     /gene="rcnR"
                     /locus_tag="ACHY1N_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HFS4042387.1"
                     /translation="MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK"
     gene            18882..19706
                     /gene="rcnA"
                     /locus_tag="ACHY1N_000022"
     CDS             18882..19706
                     /gene="rcnA"
                     /locus_tag="ACHY1N_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
                     /protein_id="HFS4042388.1"
                     /translation="MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIA
                     IKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIIGTA
                     FWMFWRTWRGERNWLENMHEYDHEHHHHDHEDHHDHGHHHHHEHGEYQDAHARAHAND
                     IKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLA
                     LTLITVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR"
     gene            19925..20263
                     /gene="rcnB"
                     /locus_tag="ACHY1N_000023"
     CDS             19925..20263
                     /gene="rcnB"
                     /locus_tag="ACHY1N_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416610.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HFS4042389.1"
                     /translation="MTIKNKMLLGALLLVTSAAWAAPATAGSTNTSGISKYELSSFIA
                     DFKHFKPGDTVPEMYRTDEYNIKQWQLRNLPAPDAGTHWTYMGGAYVLISDTDGKIIK
                     AYDGEIFYHR"
     gene            complement(20345..21379)
                     /gene="yehA"
                     /locus_tag="ACHY1N_000024"
     CDS             complement(20345..21379)
                     /gene="yehA"
                     /locus_tag="ACHY1N_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="HFS4042390.1"
                     /translation="MNIRIMLFIVMMMVMPVSYAACYSELSVQHNLVVQGDFALTQTQ
                     MATYEHNFNDSSCVSTNTITPMSPSDIIVGLYNDTIKLNLHFEWTNKNNITLSNNQTS
                     FTSGYSVTVTPAASNAKVNVSAGGGGSVMINGVATLSSASSSTRGSAAVQFLLCLLGG
                     KSWDACVNSYRNALAQNAGVYSFNLTLSYNPITTTCKPDDLLITLDSIPVSQLPATGN
                     KATINSKQGDIILRCKNLLGQQNQTSRKMQVYLSSSDLLTNSNTILKGAEDNGVGFIL
                     ESNGSSVTLLNITNSSKGYTNLKEIAAKSKLTDTTVSIPITASYYVYDTNKVKSGALE
                     ATALINVKYD"
     gene            complement(21393..23873)
                     /gene="yehB"
                     /locus_tag="ACHY1N_000025"
     CDS             complement(21393..23873)
                     /gene="yehB"
                     /locus_tag="ACHY1N_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HFS4042391.1"
                     /translation="MLRMTPLASAIVALLLGIEAYAAEETFDTHFMIGGMKDQQVANI
                     RLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPQETCLSIEVIKRLGINSDNFASGK
                     QCLTFEQLVQGRSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYV
                     SQYYSDYKASGNSKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGVWKSNTLYLERGF
                     AQLLGTLRVGDMYTSSDIFDSVRFSGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVT
                     IEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQ
                     PGVSKYDFAAGRSHIEGASKQSDFVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGTGW
                     NTRFGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRT
                     FNDHVWANNKDNYRRDENDVYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLW
                     RDYWGRSGSSKDYQLSYSNNWRRISYILAASQAYDENHHEEKRFNIFISIPFDWGDDV
                     TTPRRQIYMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSYQNQGNETTAGANL
                     TWNAPVATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDA
                     YVNGQKYRTTNRNGVVVYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVL
                     VNFDTDQRKPWFIKALRADGQPLMFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVN
                     VAIDKQQGLSCTITFGKEIDESRNYICQ"
     gene            complement(23889..24563)
                     /gene="yehC"
                     /locus_tag="ACHY1N_000026"
     CDS             complement(23889..24563)
                     /gene="yehC"
                     /locus_tag="ACHY1N_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HFS4042392.1"
                     /translation="MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQG
                     NRSSLLQAWIDDGDTSLPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKES
                     IFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
                     LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWYLTIIDDHGN
                     YISDKI"
     gene            complement(24644..25186)
                     /gene="yehD"
                     /locus_tag="ACHY1N_000027"
     CDS             complement(24644..25186)
                     /gene="yehD"
                     /locus_tag="ACHY1N_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4042393.1"
                     /translation="MKRSIIAAAVFSSFFMSAGVFAADVDTGTLTIKGNIAESPCKFE
                     AGGDSVSINMPTVPTTVFEGKAKYSTYDDAVGVTSSMLKISCPKEVAGVKLSLITNDK
                     ITGNDKAIASSNDTVGYYLYLGDNSDVLDVSAPFNIESYKTAEGQYAIPFKAKYLKLT
                     DNSVQSGDVLSSLVMRVAQD"
     gene            complement(25479..25760)
                     /gene="yehE"
                     /locus_tag="ACHY1N_000028"
     CDS             complement(25479..25760)
                     /gene="yehE"
                     /locus_tag="ACHY1N_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehE family protein"
                     /protein_id="HFS4042394.1"
                     /translation="MNKYWLSGIIFLAYGLASPAFSSETATLAINGRISPPTCSMAMV
                     NGQPQQHCGQLTYNVDTRHLFSSPVKGVTTEVVVAGSDSKRRIVLNRYD"
     gene            complement(26023..27132)
                     /gene="apbC"
                     /locus_tag="ACHY1N_000029"
     CDS             complement(26023..27132)
                     /gene="apbC"
                     /locus_tag="ACHY1N_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HFS4042395.1"
                     /translation="MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
                     RPTSPDGTHMAPIVSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPGLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDKGTPTVISRP
                     ESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV"
     gene            27264..29297
                     /gene="metG"
                     /locus_tag="ACHY1N_000030"
     CDS             27264..29297
                     /gene="metG"
                     /locus_tag="ACHY1N_000030"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFS4042396.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEE
                     NRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSV
                     SFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALAD
                     LANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLN
                     TELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDP
                     IQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK"
     gene            29438..33232
                     /locus_tag="ACHY1N_000031"
     CDS             29438..33232
                     /locus_tag="ACHY1N_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HFS4042397.1"
                     /translation="MRHFIYQDEKSHKFWAVEQQGNELHISWGKVGTKGQSQIKSFSD
                     AAAVAKAELKLIAEKVKKGYVEQAKDNSLQPSQTVTGSLKVADLSTIIQEQPSFVAET
                     RAPDKNTDAVLPWLAKDIAVVFPPEVVHTTLSHRRFPGVPVQQADKLTQLRRLACSVS
                     QRDNKTATFDFSACSLEWQNTVAQAISQIDGLKTTQLPSPVMAVLTALEMKCTRYKVR
                     EDVMDQIVQEGGLEYATDVIIHLQQIDIKWDYANNVIIILPSGIAPDYLEQYSRFELR
                     LRKHLSLAEESLWQKCAQKLIAAIPHIPEWRQPLIALLLPEKPEIAHEIAQRLLGQKK
                     LPSLEWLKIVATDEHILASLEKYHEPYAIFDDYYCGAIWSATVLQEQGVAALPRFAPY
                     AASDYCADVLRHINHPFALTLLIRVAGHTKRCHDRMTKACAAFPHAAMAALTELLGQK
                     EENSWRIMLMTMLISQPALAEQVIPWLSTPAVAVLKSCQQQLTQPSNHASADLLPAVV
                     VSPPWLSKKKKSPIPVLDLAPLGIEPICYLTEEISNQLLAKYIWYSKHITVSHEESTT
                     NLLARMGFQRRIAGTYIKAPEAVVEAWLNEDYSTLLSEFKVFHSPTGHYWQLGILTTL
                     PLEKAVKAWNALTLSPHTDTEYAMLHFGLKGLPGLVNSLARYPQEALPITNYFAASEL
                     APAVARAFNKLKTLRENARSWLLKYPEHALTGLLPAALGKAGEAQDNARAALRMLTEN
                     GHQPLLQEIARRYNQPEVTDAVNALLALDPLDNHPTKIPTLPAFYQPSLWTRPVLKAN
                     AQSLPDSALLHLGEMLRFPQEEALYPGLLQVKDVCSADSLAGFAWDLFTAWQTAGAPS
                     KESWAFTALGVLGNDDTARKLTPLIRAWPGESQHKRATVGLDILAAIGSDIALMQLNG
                     IAQKLKFKALQERAKEKIADIAESRELTVAELEDRLAPDLGLDDNGSLLLDFGPRQFT
                     VSFDETLKPFVRDVSGSRLKDLPKPNKSDDETRANDAVNRYKLLKKDARTIAAQQVAR
                     LESAMCLRRRWSLENFQLFLVEHPLVRHLTRRLIWGVYSAENQLLACFRVAEDNSYST
                     ADDDLFTLPEGDISIGTPHVLEISPTDAAAFGQLFADYELLPPFRQLDRNSYALTEAE
                     RNASELTRWAGRKCPSGRVMGLANKGWVRGEPQDGGWIGWMIKPLGRWSLIMEIDEGF
                     AVGMSPAELSAEQLLSKLWLWEGKAESYGWGSNSTQEAQFSVLDAITASELINDIEAL
                     FE"
     gene            33242..36874
                     /gene="yehI"
                     /locus_tag="ACHY1N_000032"
     CDS             33242..36874
                     /gene="yehI"
                     /locus_tag="ACHY1N_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein YehI"
                     /protein_id="HFS4042398.1"
                     /translation="MDKELPWLADNAQLELKYKKGKTPLSHRNWPGEPVPVITESIIQ
                     TLGDELLQKAEKKKNIVWRYENFSLEWQSAITQAINLIGEHKPSIPAQTMAALVCIAQ
                     NDSQQLLDEIVQQEGLEYATEVVIARQFITRCYESDPLVVTLQYQNEDYGYGYRSETY
                     NEFDLRLRKHLSLAEESCWQRCADKLIATLPGITKVRRPFIALILPEKPEIANELVSL
                     ECPRTHFHSKEWLKVVANDPTAVRKLERYWSQDIFSDREASYMSHENHFGYAACAALL
                     REQGLAAVPRLAIYAHKEDCGSLLVQINHPQVIRTLLLVADKNKPSLQRVAKYSKNFP
                     HATLAALAELLALKEPPARLGYPIIEDKKLPAQQKARDEYWRTLLQTLIASQPQLAER
                     VMPWLSTQARAVLNSYLSAPPKPVIDSTDNSSLPEMLVSPPWRSKKKMTAPRLDLAPL
                     ELTPQIYWQPGEQERLAATESARYFSTESLAERMEQKSGRVVLQELGFGDDVWLFLNY
                     ILPGKLDAARNSLIVQWHYYQGRVEEILNGWNSPQAQLAEQALRSGHIEALINIWEND
                     NFSRYRPEKSVWNLYLLAQLPREMALTFWLRIIEKKHLFAGEDYFLSILGLDALPGLL
                     LAFSHRPKETFPLILNFGATELALPVARVWRRFAAQRDLARQWILQWPEHTASALIPL
                     VFTKPSDNSEAALLALRLLYEQGHGELLQTVANRWQRTDVWSALEQLLKQGPMDIYPA
                     RIPKAPDFWHPAMWSRPRLITNNQPVTGDALEIIGEMLRFTQGGRFYSGLEQLKTFCQ
                     PQTLAAFAWDLFTAWQQAGAPAKDNWAFLALSLFGDESTARDLTTQILAWPQEGKSAR
                     AVSGLNILTLMNNDMALIQLHHISQRAKSRPLRDNAAEFLQVVAENRGLSQEELADRL
                     VPTLGLDDPQALSFDFGPRQFTVRFDENLNPVIFDQQNVRQKSVPRLRADDDQLKAPE
                     ALARLKGLKKDATQVSKNLLPRLEAALRTTRRWSLADFHTLFVNHPFTRLVTQRLIWG
                     VYPANEPRRLLNAFRVAAEGEFCNAQDEPIDLPADALIGIAHPLEMTAEMRSEFAQLF
                     ADYEIIPPLRQLTRRTVLLTPDESASNSLNRWEGKSATVGQLMGMRYKGWESGYEDAF
                     VYDLGEYRLVLKFSPGFNHYNVDSKALMSFRSLRVYSDNKSVTFAELDVFDLSEALSA
                     PDVIFH"
     gene            36935..37255
                     /gene="yehK"
                     /locus_tag="ACHY1N_000033"
     CDS             36935..37255
                     /gene="yehK"
                     /locus_tag="ACHY1N_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YehK"
                     /protein_id="HFS4042399.1"
                     /translation="MIVQKELVAIYDYEVPVPEDPFSFRLEIHKCSELFTGSVYRLER
                     FRLRPTFHQRDREDADPLINDALIYIRDECIDERKLRGESPETVIAIFNRELQNIFNQ
                     LIEY"
     gene            38438..39526
                     /gene="yehL"
                     /locus_tag="ACHY1N_000034"
     CDS             38438..39526
                     /gene="yehL"
                     /locus_tag="ACHY1N_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HFS4042400.1"
                     /translation="MSPQNNHLQRPPAAVLYADELAKLKQNDNAPCPPGWQLSLPAAR
                     AFILGDSAQNISRKVVISPSAVERMLVTLATGRGLMLVGEPGTAKSLLSELLATAISG
                     DAGLTIQGGASTTEDQIKYGWNYTLLINHGPSTEALVPAPLYQGMRDGKIVRFEEITR
                     TPLEVQDCLLGMLSDRVMTVPELTGEASQLYAREGFNIIATANTRDRGVNEMSAALKR
                     RFDFETVFPIMDFAQELELVASASARLLAHSGIPHKVPDAVLELLVRTFRDLRANGEK
                     KTSMDTLTAIMSTAEAVNVAHAVGVRAWFLANRAGEPADLVDCIAGTIVKDNEEDRAR
                     LRRYFEQRVATHKEAHWQAYYQARHRLP"
     gene            39537..41740
                     /gene="yehM"
                     /locus_tag="ACHY1N_000035"
                     /pseudo
     CDS             39537..41740
                     /gene="yehM"
                     /locus_tag="ACHY1N_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416624.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5682 family protein"
     gene            41733..42869
                     /gene="yehP"
                     /locus_tag="ACHY1N_000036"
     CDS             41733..42869
                     /gene="yehP"
                     /locus_tag="ACHY1N_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HFS4042401.1"
                     /translation="MSELNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEW
                     LYGRDPERLQRGERSGGLGGSNLTTPEWINSIHTLFPQQVIERLESDAVLRYGIEDVV
                     TNLDVLERMQPSESLLRAVLHTKHLMNPEVLAAARQIVRQVVEEIMARLAKEVRQAFS
                     GVRDRRRRSLIPLARNFDFKSTLRANLQHWHPQHGKLYIESPRFNSRIKRQSEQWQLV
                     LLVDQSGSMVDSVIHSAVMAACLWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQ
                     LGGGTNIASAVEYGRQLIEQPAKSVIILVSDFYEGGSSSLLTHQVKKCVQSGIKVLGL
                     AALDSTATPCYDRDTAQALVNVGAQIAAMTPGELASWLAENLQS"
     gene            42866..44866
                     /gene="yehQ"
                     /locus_tag="ACHY1N_000037"
     CDS             42866..44866
                     /gene="yehQ"
                     /locus_tag="ACHY1N_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFS4042402.1"
                     /translation="MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHEN
                     GALIATFSDGVRTQLANSQALKEAQCSCGASGMCRHRVMLVLSYQRLCATVQPTEKEE
                     EWDPAIWLEELATLPDATRKRAQALVAKGITIELFCAPGEIPSARLPMSDVRFYSRSS
                     IRFARCDCIEGTLCEHVVLAVQAFVEAKAQQAEFNHLIWQMRSEHVTSSDDPFASEEG
                     QTCRQYVQQLSQALWLGGISQPLIHYEAAFNRTLQAAEACNWRWVSESLRQLRASVDA
                     FHTRASHYHAGECLRQLAALNSRLNCAQEMARRDSVGEVPPVPWRTVVGSGIAGEAKL
                     DHLRLVSLGMRCWQDIEHYGLRIWFTDPDTGSILHLSRSWPRSEQENSPAATRRLFSF
                     QAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWQMLSAPLRQPGIVALR
                     EYLRQRPPACIRPLNQVDNLFILPVAECISLGWDSSRQTLDAQVISGEGEDNLLTLSL
                     PASACSPFAVERMAALLQQTDDPVSLVSGFVSFVDGQLTLEPRVMMTKTRAWALDAET
                     APVAPLPSASVLPVPSTAHQLLMRCQALLIQLLHNGWRYQEQSAISQAELLANDLSAV
                     GFYRLAHVLGQFRNTESEARVEAMNNGVLLCEQLFPMLQQQG"
     gene            44991..45452
                     /gene="yehR"
                     /locus_tag="ACHY1N_000038"
                     /pseudo
     CDS             44991..45452
                     /gene="yehR"
                     /locus_tag="ACHY1N_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416627.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
     gene            complement(45493..45963)
                     /gene="yehS"
                     /locus_tag="ACHY1N_000039"
     CDS             complement(45493..45963)
                     /gene="yehS"
                     /locus_tag="ACHY1N_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HFS4042403.1"
                     /translation="MLSNDILRSVRYILKANNNDLVRILALGNVEATAEQIAVWLRKE
                     DEEGFQRCPDIVLSSFLNGLIYEKRGKDESAPALEPERRINNNIVLKKLRIAFSLKTD
                     DILAILTEQQFRVSMPEITAMMRAPDHKNFRECGDQFLRYFLRGLAARQHVKKS"
     gene            complement(46010..46729)
                     /gene="btsR"
                     /locus_tag="ACHY1N_000040"
                     /gene_synonym="yehT"
     CDS             complement(46010..46729)
                     /gene="btsR"
                     /locus_tag="ACHY1N_000040"
                     /gene_synonym="yehT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310963.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HFS4042404.1"
                     /translation="MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVH
                     KLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRM
                     SGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            complement(46726..48411)
                     /gene="btsS"
                     /locus_tag="ACHY1N_000041"
     CDS             complement(46726..48411)
                     /gene="btsS"
                     /locus_tag="ACHY1N_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system sensor histidine
                     kinase BtsS"
                     /protein_id="HFS4042405.1"
                     /translation="MYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKF
                     LCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILA
                     IARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAAS
                     TEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISST
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEFVTLADEIEHVNAYLQIEKARFQSRLQV
                     NIAIPQELSQQQLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNA
                     GLYQPVTNASGLGMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLPWRDEA"
     gene            48633..49364
                     /gene="mlrA"
                     /locus_tag="ACHY1N_000042"
     CDS             48633..49364
                     /gene="mlrA"
                     /locus_tag="ACHY1N_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
                     /protein_id="HFS4042406.1"
                     /translation="MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFND
                     ADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRT
                     WIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKK
                     QGKDALVVGWNIQDTTRLWLEGWIASQQGWRIDVLAHSLNQLRPELFEGRTLLVWCGE
                     NRTSAQQQQLTSWQEQGHDILPLGI"
     gene            49424..49531
                     /gene="yohO"
                     /locus_tag="ACHY1N_000043"
     CDS             49424..49531
                     /gene="yohO"
                     /locus_tag="ACHY1N_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HFS4042407.1"
                     /translation="MRIAKIGVIALFLFMAFGGIGGVMLAGYTFILRAG"
     gene            complement(49512..50243)
                     /gene="yehW"
                     /locus_tag="ACHY1N_000044"
     CDS             complement(49512..50243)
                     /gene="yehW"
                     /locus_tag="ACHY1N_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehW"
                     /protein_id="HFS4042408.1"
                     /translation="MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPPVAV
                     LAIAVPVIGFGLQPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRLR
                     KVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIADRLFERLVQALSQHAK"
     gene            complement(50248..51174)
                     /gene="yehX"
                     /locus_tag="ACHY1N_000045"
     CDS             complement(50248..51174)
                     /gene="yehX"
                     /locus_tag="ACHY1N_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter ATP binding
                     protein YehX"
                     /protein_id="HFS4042409.1"
                     /translation="MIEFSHVSKLFGAQKAVNDLNLNFQEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGEIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWSVAQNIATVPQL
                     QKWSRARIDDRIDELMTLLGLESNLRERYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDHGEVVQQGN
                     PLTMLTRPANDFVRQFFGRSELGVRLLSLRSVADYVRREERAEGEALVEEMTLRDALS
                     LFVARGCEVLPVVNTQGQPCGTLHFQDLLVEA"
     gene            complement(51167..52324)
                     /gene="yehY"
                     /locus_tag="ACHY1N_000046"
     CDS             complement(51167..52324)
                     /gene="yehY"
                     /locus_tag="ACHY1N_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehY"
                     /protein_id="HFS4042410.1"
                     /translation="MTYLRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQL
                     WPQTIWMLVGVGCAWLTACFVPAKKGSICALILAQFVFVLLVWGAGKAATQLAQNGSA
                     LARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDL
                     SLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNV
                     IQTVPSVALFGLLIAPLAALVTAFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVV
                     GLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIG
                     AGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLIDALFDLLIALLKVKRND"
     gene            complement(52331..53248)
                     /gene="osmF"
                     /locus_tag="ACHY1N_000047"
     CDS             complement(52331..53248)
                     /gene="osmF"
                     /locus_tag="ACHY1N_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein OsmF"
                     /protein_id="HFS4042411.1"
                     /translation="MPLLKLWAGSLVMLAAVSLPLQAASPVKVGSKIDTEGALLGNII
                     LQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYPEYTGNGAFFFKDENDAAWKNAQ
                     QGYEKVKKLDSEHNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLSRYLQEGGTF
                     KLAASAEFIERADALPAFEKAYGFKLGQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPQGVQPIYAPAPVVRESVLKEYPQMAQWLQPVFASLDAKTL
                     QQLNASIAVEGLDAKKVAADYLKQKGWAK"
     gene            complement(53459..55756)
                     /gene="bglX"
                     /locus_tag="ACHY1N_000048"
     CDS             complement(53459..55756)
                     /gene="bglX"
                     /locus_tag="ACHY1N_000048"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HFS4042412.1"
                     /translation="MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRL
                     KIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSTMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     QWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLINS
                     GKVTMEELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVAR
                     ESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNSV
                     GENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAV
                     VGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKP
                     NKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKRE
                     GATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGTDSARVKKGEFELL"
     gene            55952..57667
                     /gene="dld"
                     /locus_tag="ACHY1N_000049"
     CDS             55952..57667
                     /gene="dld"
                     /locus_tag="ACHY1N_000049"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016901 - oxidoreductase activity, acting
                     on the CH-OH group of donors, quinone or similar compound
                     as acceptor [Evidence IEA];
                     GO_process: GO:0006089 - lactate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HFS4042413.1"
                     /translation="MSSMTTTDNKAFLNELARLVGHSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNDYDRDIVIISTL
                     RLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRH
                     DGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQ
                     QVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEKYGKDTFLMIDKLGT
                     DKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSD
                     EVEDILALDIALRRNDTEWYEHLPPEIDSQLVHKLYYGHFMCYVFHQDYIVKKGVDVH
                     ALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGKTSKRKN
                     WQEVE"
     gene            complement(57705..58637)
                     /gene="pbpG"
                     /locus_tag="ACHY1N_000050"
     CDS             complement(57705..58637)
                     /gene="pbpG"
                     /locus_tag="ACHY1N_000050"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311048.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HFS4042414.1"
                     /translation="MPKFRVSLFSLALMLAVPLAPQAVAKTAAATAASQPEIASGSAM
                     IVDLNTNKVIYSNHPDLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVY
                     SRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTR
                     FVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNH
                     LVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTW
                     IETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND"
     gene            complement(58811..59398)
                     /gene="yohC"
                     /locus_tag="ACHY1N_000051"
     CDS             complement(58811..59398)
                     /gene="yohC"
                     /locus_tag="ACHY1N_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0031267 - small GTPase binding [Evidence
                     IEA];
                     GO_process: GO:0006888 - endoplasmic reticulum to Golgi
                     vesicle-mediated transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Yip1 family protein"
                     /protein_id="HFS4042415.1"
                     /translation="MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICA
                     FIGTTQIGWNFGDGTILKLSWFTGLALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LAHCMVFAGYVATPLFLSGLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKE
                     EGLSFSSSTLAIGVLVLEVLLALTVILWGYGYRLF"
     gene            59568..60146
                     /gene="yohD"
                     /locus_tag="ACHY1N_000052"
     CDS             59568..60146
                     /gene="yohD"
                     /locus_tag="ACHY1N_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFS4042416.1"
                     /translation="MDLNTLISQYGYAALVIGSLAEGETVTLLGGVAAHQGLLKFPLV
                     VLSVAFGGMIGDQVLYLCGRRFGGKLLRRFSKHQDKIERAQKLIQRHPYLFVIGTRFM
                     YGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHNLDQHL
                     KHWVWLILVVVLVVGVRWWLKRRGKKKPDHQA"
     gene            complement(60276..61037)
                     /gene="yohF"
                     /locus_tag="ACHY1N_000053"
     CDS             complement(60276..61037)
                     /gene="yohF"
                     /locus_tag="ACHY1N_000053"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4042417.1"
                     /translation="MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTA
                     REVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFD
                     EWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
                     GGLTKTMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIA
                     SLVAWLCSEGANYTTGQSLIVDGGFMLANPQFNPE"
     gene            complement(61090..62526)
                     /gene="mdtQ"
                     /locus_tag="ACHY1N_000054"
     CDS             complement(61090..62526)
                     /gene="mdtQ"
                     /locus_tag="ACHY1N_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001583680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HFS4042418.1"
                     /translation="MNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTA
                     LPTALKNGWPDSQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAIATQD
                     GPQIDFSADMERQKMSAEGLMGPFALNDPAAGTTGPWYTNGTFGLTAGWHLDIWGKNR
                     AEVTARLGTVKARAAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQNTIIAT
                     DRQLYQNGITSSVDGVETDINASKTRQQLNDVAGKMKIIEARLSALTNNQTKSLKLKP
                     VALPKVASQLPDELGYSLLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQ
                     DALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIAKAGSNLSIASYNKAVVEAV
                     NDVARAASQVQTLAEKNQHQAQIERDALRVVGLAQARFNAGIIAGSRVSEARIPALRE
                     RANGLLLQGQWLDASIQLTGALGGGYKR"
     gene            62750..62833
                     /gene="yohP"
                     /locus_tag="ACHY1N_000055"
     CDS             62750..62833
                     /gene="yohP"
                     /locus_tag="ACHY1N_000055"
                     /inference="COORDINATES: protein motif:HMM:NF011345.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small membrane protein YohP"
                     /protein_id="HFS4042419.1"
                     /translation="MKIILWAVLIIFLIGLLVVTGVFKMIF"
     gene            complement(63221..64171)
                     /gene="dusC"
                     /locus_tag="ACHY1N_000056"
     CDS             complement(63221..64171)
                     /gene="dusC"
                     /locus_tag="ACHY1N_000056"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0002943 - tRNA dihydrouridine synthesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HFS4042420.1"
                     /translation="MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKT
                     VNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQA
                     GATELVVHGRTKEQGYRAEHIDWQAIGDIRQRLNIPVIANGEIWDWQSAQQCMAISGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQW
                     LSYLRKEYDEATGLFQHVRVLNNSPDIARAIQAIDIDKLR"
     gene            64410..64808
                     /gene="yohJ"
                     /locus_tag="ACHY1N_000057"
     CDS             64410..64808
                     /gene="yohJ"
                     /locus_tag="ACHY1N_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFS4042421.1"
                     /translation="MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAV
                     STLVVFLVVSWSSQLVHGERKVVGQKGSEE"
     gene            64805..65500
                     /gene="yohK"
                     /locus_tag="ACHY1N_000058"
     CDS             64805..65500
                     /gene="yohK"
                     /locus_tag="ACHY1N_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HFS4042422.1"
                     /translation="MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPF
                     LMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVA
                     MVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLI
                     APFLFPIILAVMG"
     gene            65630..66514
                     /gene="cdd"
                     /locus_tag="ACHY1N_000059"
     CDS             65630..66514
                     /gene="cdd"
                     /locus_tag="ACHY1N_000059"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFS4042423.1"
                     /translation="MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSA
                     TGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVH
                     AEQSAISHAWLSGEEALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDY
                     LPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECK
                     DGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDAT
                     SATLKALGCHSIDRVLLA"
     gene            66664..67383
                     /gene="sanA"
                     /locus_tag="ACHY1N_000060"
     CDS             66664..67383
                     /gene="sanA"
                     /locus_tag="ACHY1N_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HFS4042424.1"
                     /translation="MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPED
                     AQGYPAVTPEQLLELQKKQGK"
     gene            67386..67625
                     /gene="yeiS"
                     /locus_tag="ACHY1N_000061"
     CDS             67386..67625
                     /gene="yeiS"
                     /locus_tag="ACHY1N_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HFS4042425.1"
                     /translation="MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVY
                     VWRAKNPGLFFAYMVAYIGFGILSIGMIVYLIFYR"
     gene            67944..69182
                     /gene="preT"
                     /locus_tag="ACHY1N_000062"
     CDS             67944..69182
                     /gene="preT"
                     /locus_tag="ACHY1N_000062"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreT"
                     /protein_id="HFS4042426.1"
                     /translation="MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQSGCTRAGVDAPIDIGRLQ
                     RFVTDFEQQTGMEIYQPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAHPG
                     GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEVGNTLTLEQLKAENRAVLVTVG
                     LSSGSGLLLFEHSDVEIAVDFLQRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLG
                     CQAVTCVAREELDEFPASEKEFASARELGVSIIDGFTPVAVEGNKVTFKHVRLPGELT
                     MAADKIILAVGQHARLDAFAELEPQRNTINTQNYQTRDPQVFAAGDIVEGDKTVVYAV
                     KTGKEAAEAIHHYLEGACSC"
     gene            69176..70411
                     /gene="preA"
                     /locus_tag="ACHY1N_000063"
     CDS             69176..70411
                     /gene="preA"
                     /locus_tag="ACHY1N_000063"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017113 - dihydropyrimidine dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0006210 - thymine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006212 - uracil catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="HFS4042427.1"
                     /translation="MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGV
                     VFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRRLKEDYPDK
                     VLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYC
                     RAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMP
                     IVNGKSSISGYSGKAVKPIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGA
                     ATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLANNNIVPAEDLDRSYI
                     VYPRINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGC
                     IELGEVKFKKGEKEHPVTL"
     gene            complement(70482..71492)
                     /gene="mglC"
                     /locus_tag="ACHY1N_000064"
     CDS             complement(70482..71492)
                     /gene="mglC"
                     /locus_tag="ACHY1N_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HFS4042428.1"
                     /translation="MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMAT
                     MPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVGLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYAR
                     KK"
     gene            complement(71508..73028)
                     /gene="mglA"
                     /locus_tag="ACHY1N_000065"
     CDS             complement(71508..73028)
                     /gene="mglA"
                     /locus_tag="ACHY1N_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0043211 - ABC-type carbohydrate
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     ATP-binding protein MglA"
                     /protein_id="HFS4042429.1"
                     /translation="MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHAL
                     MGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQ
                     RSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
                     AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDE
                     VTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQ
                     PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKQINNHNANE
                     AINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDS
                     MRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIA
                     ELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQNEILRLASLHL"
     gene            complement(73089..74087)
                     /gene="mglB"
                     /locus_tag="ACHY1N_000066"
     CDS             complement(73089..74087)
                     /gene="mglB"
                     /locus_tag="ACHY1N_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HFS4042430.1"
                     /translation="MNKKVLTLSAVMASMLFGAAAHAADTRIGVTIYKYDDNFMSVVR
                     KAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNK
                     DGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGALAGT
                     VLNDANNQAKATFDLAKNLADGKGAADGTNWKIDNKVVRVPYVGVDKDNLAEFSKK"
     gene            complement(74367..75407)
                     /gene="galS"
                     /locus_tag="ACHY1N_000067"
     CDS             complement(74367..75407)
                     /gene="galS"
                     /locus_tag="ACHY1N_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HFS4042431.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELD
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYAHRCVCLDN
                     LSGARMATRMLLNNGHQRIGYLSSSHGIEDDAMRKAGWMSALKEQDIIPPESWIGTGT
                     PDMPGGEAAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIP
                     IARYTDPQLTTVRYPIASMTKLATELALQGAAGNIDSRASHCFMPTLVRRHSVATRQN
                     AAAITNSTNQAM"
     gene            complement(75549..76706)
                     /gene="yeiB"
                     /locus_tag="ACHY1N_000068"
     CDS             complement(75549..76706)
                     /gene="yeiB"
                     /locus_tag="ACHY1N_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 domain-containing protein YeiB"
                     /protein_id="HFS4042432.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITP
                     QDAWTWAFLDLIGQVKFLTLFALLFGAGLQMLLPRGRRWIQSRLTLLVLLGFIHGLLF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRA
                     WTPDASAILYEKYWKLHGGVDAISNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRS
                     GWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQWQLDWAYRWCAFLLQMPRELSAPF
                     QAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLGLFMHFDR
                     LELLAFVIPVWLANILFSVIWLRYFRQGPVEWLWRQLTLRAAGPAISKTSR"
     gene            complement(76723..77391)
                     /gene="folE"
                     /locus_tag="ACHY1N_000069"
     CDS             complement(76723..77391)
                     /gene="folE"
                     /locus_tag="ACHY1N_000069"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HFS4042433.1"
                     /translation="MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHM
                     TEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     IALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAV
                     RHHN"
     gene            77649..78485
                     /gene="yeiG"
                     /locus_tag="ACHY1N_000070"
     CDS             77649..78485
                     /gene="yeiG"
                     /locus_tag="ACHY1N_000070"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HFS4042434.1"
                     /translation="MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPP
                     VLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEKVANDDGYDLGQGAGF
                     YLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPG
                     KYTSVSAFAPIVNPCSVPWGIKAFSRYLGEDKNAWLEWDSCALMYASNAQDAIPTLID
                     QGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYL
                     LK"
     gene            complement(78517..80508)
                     /gene="cirA"
                     /locus_tag="ACHY1N_000071"
     CDS             complement(78517..80508)
                     /gene="cirA"
                     /locus_tag="ACHY1N_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
                     /protein_id="HFS4042435.1"
                     /translation="MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNL
                     KDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLIL
                     VDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKI
                     GQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNS
                     TTTDTGETPRIEGFSSRDGNVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQN
                     YSVSHNGRWDYGTSELKYYGEKVENKNPGNSSPITSESNTVDGKYTLPLTAINQFLTV
                     GGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGE
                     HWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPE
                     TSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAPGYQNFVGFET
                     GANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTYNDGRDVSNGENKPLS
                     DLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNTGAAWQVT
                     KDVKLRAGVLNLGDKDLSRDDYSYNEDGRRYFMAVDYRF"
     gene            complement(80801..82270)
                     /gene="lysP"
                     /locus_tag="ACHY1N_000072"
     CDS             complement(80801..82270)
                     /gene="lysP"
                     /locus_tag="ACHY1N_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HFS4042436.1"
                     /translation="MVSETKTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     QAGPGGALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFS
                     LIKVTTVIVFIIVGVLMIIGIFKGAQPAGWSNWTIGEAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESEDPAKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPSLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPH
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGHDINDLPYRSGFFPLGPIFAFILCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLIIWFGYKLIKGTHFVRYSEMKFPQNDKK"
     gene            complement(82475..83356)
                     /gene="yieE"
                     /locus_tag="ACHY1N_000073"
     CDS             complement(82475..83356)
                     /gene="yieE"
                     /locus_tag="ACHY1N_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YeiE"
                     /protein_id="HFS4042437.1"
                     /translation="MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQ
                     LGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNY
                     ILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLE
                     DELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMEL
                     GNSEAIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLS
                     NALRRFLDYCDPANVPR"
     gene            83455..84504
                     /gene="yeiH"
                     /locus_tag="ACHY1N_000074"
     CDS             83455..84504
                     /gene="yeiH"
                     /locus_tag="ACHY1N_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HFS4042438.1"
                     /translation="MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGF
                     SALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYLLRLGIILYGFRLTFSQIADVGI
                     SGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAI
                     SPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGANSGEKSKITIPWFAILFIVVAI
                     FNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLI
                     VGGGAINYVIQSVIA"
     gene            84578..85435
                     /gene="nfo"
                     /locus_tag="ACHY1N_000075"
     CDS             84578..85435
                     /gene="nfo"
                     /locus_tag="ACHY1N_000075"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFS4042439.1"
                     /translation="MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPL
                     TTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLG
                     LSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEH
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLN
                     DAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLK
                     AQQTEKAVA"
     gene            85439..86527
                     /locus_tag="ACHY1N_000076"
     CDS             85439..86527
                     /locus_tag="ACHY1N_000076"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HFS4042440.1"
                     /translation="MNDREKQILKILRRNPLIQQNEIADILQISRSRVAAHIMDLMRK
                     GLIKGKGYILTEQDYCVVVGAINMDIRGMADIRYPQAASHPGSVHCSAGGVGRNIAHN
                     LALLGRDVHLISAIGNDFYGETLLEETRRAGVNVSNCIRLHGHSTATYLAIANKQEET
                     ILAINDTHILQQLTPQLLNTSRDLIRHAGVVLADCNLTPEALEWVFTIADEIPMFVDT
                     VSEFKANKVKNWYSRIHTLKPTQNELEILWGQPIKDDNDRIRAVNSLHQQGVKRIFVY
                     LKDESVFCSDKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFLEGYSFRDSARFAVA
                     CAAISRASGSLNNPTLSADNALSLVPMV"
     gene            complement(86583..87833)
                     /gene="nupX"
                     /locus_tag="ACHY1N_000077"
     CDS             complement(86583..87833)
                     /gene="nupX"
                     /locus_tag="ACHY1N_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:1901642 - nucleoside transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HFS4042441.1"
                     /translation="MDVMRSVLGMVVLLAIAFLLSVNKKKISLRTVGAALVLQVVIGG
                     IMLWLPPGRWVAEKVAFGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVL
                     PAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFAR
                     LLSPATESSQVSFNNLSFTETPPKSIIEAAATGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFAHASLESILGYLLAPLAWVMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTGGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(87933..88874)
                     /gene="rihB"
                     /locus_tag="ACHY1N_000078"
     CDS             complement(87933..88874)
                     /gene="rihB"
                     /locus_tag="ACHY1N_000078"
                     /EC_number="3.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosylpyrimidine nucleosidase"
                     /protein_id="HFS4042442.1"
                     /translation="MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLD
                     KTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAEST
                     HAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFT
                     PSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSD
                     IMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCD
                     ELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH"
     gene            89004..89702
                     /gene="yeiL"
                     /locus_tag="ACHY1N_000079"
     CDS             89004..89702
                     /gene="yeiL"
                     /locus_tag="ACHY1N_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311082.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator YeiL"
                     /protein_id="HFS4042443.1"
                     /translation="MKEIHNNDLKQQLMSESAFKDCFLTDVSADTRLFHFLARDYIVQ
                     EGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIE
                     ECWCLALPMKHYRPRLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
                     LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFIHDGLLTKSKKGYLIKNRKQLSGLA
                     LEMDPENKFSGMMQ"
     gene            complement(89773..91023)
                     /gene="psuT"
                     /locus_tag="ACHY1N_000080"
     CDS             complement(89773..91023)
                     /gene="psuT"
                     /locus_tag="ACHY1N_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:1901642 - nucleoside transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HFS4042444.1"
                     /translation="MDIMRSVVGMVVLLAIAFVLSVNKKSISLRTVGAALLLQIAIGG
                     IMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVL
                     PAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFAR
                     ILSPATEPSQVTFENLSFSETPPKSIIEAAANGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFANVSLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTSGTLDVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(91117..92055)
                     /gene="psuG"
                     /locus_tag="ACHY1N_000081"
     CDS             complement(91117..92055)
                     /gene="psuG"
                     /locus_tag="ACHY1N_000081"
                     /EC_number="4.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HFS4042445.1"
                     /translation="MSELKISPELLQISPEVQDALKNKKPVVALESTIISHGMPFPQN
                     AQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFV
                     VAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTV
                     VCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFEVSIRLDSAREIARA
                     MAVKWQTGLNGGLVVANPIPEQFAMPEETINAAIDQAVAEAEEQGVIGKESTPFLLAR
                     VAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLVG"
     gene            complement(92043..92984)
                     /gene="psuK"
                     /locus_tag="ACHY1N_000082"
     CDS             complement(92043..92984)
                     /gene="psuK"
                     /locus_tag="ACHY1N_000082"
                     /EC_number="2.7.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine kinase"
                     /protein_id="HFS4042446.1"
                     /translation="MREKDYVVIIGSANIDVAGYSHESLNYADSNPGKIKFTPGGVGR
                     NIAQNLALLGNKAWLLSAVGSDFYGQSLLTQTNQSGVYVDKCLIVPGENTSSYLSLLD
                     NTGEMLVAINDMNISNAITAEYLAQHREFIQRAKVIVADCNISEEALAWILDNAANVP
                     VFVDPVSAWKCVKVRDRLNQIHTLKPNRLEAETLSGIALSGRGDVAKVAAWFHQHGLN
                     RLVLSMGGDGVYYSDISGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFAESV
                     RFAQGCSSMALSCEYTNNPDLSIANVISLVENAECLN"
     gene            complement(93408..95099)
                     /gene="fruA"
                     /locus_tag="ACHY1N_000083"
     CDS             complement(93408..95099)
                     /gene="fruA"
                     /locus_tag="ACHY1N_000083"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HFS4042447.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMA
                     IVLGDSIPNDSALNGKNVWLGDISRAVAHPELFLSEAKGHAKPYTAPVTATAPVAASG
                     PKRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAAD
                     LVIVAADIEVDLAKFAGKPMYRTSTGLALKKTAQELDKAVAEATPYEPAGKAQTATSE
                     GKKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGS
                     AFALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYIAKLIS
                     TQLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILEGLTHWLQTMGTANAV
                     LLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYGPMAAIMAAGMVPPLAMGLATMV
                     ARRKFDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIG
                     AKLMAPHGGLFVLLIPGAITPVLGYLVAIIAGTLVAGLAYAFLKRPEVDAVAKAA"
     gene            complement(95116..96054)
                     /gene="fruK"
                     /locus_tag="ACHY1N_000084"
     CDS             complement(95116..96054)
                     /gene="fruK"
                     /locus_tag="ACHY1N_000084"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFS4042448.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            complement(96054..97184)
                     /gene="fruB"
                     /locus_tag="ACHY1N_000085"
     CDS             complement(96054..97184)
                     /gene="fruB"
                     /locus_tag="ACHY1N_000085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HFS4042449.1"
                     /translation="MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSAPTAEELRALLMGEKQSEQLKLDNEMLTLDIV
                     ASDLLTLQALNAARLKEARAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVS
                     RAANAFDVDGETAAMLVSVAMNDDQPIAVLKRLADLLLDNKADRLLKADAATLLALLT
                     SDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA"
     gene            97552..98730
                     /gene="setB"
                     /locus_tag="ACHY1N_000086"
     CDS             97552..98730
                     /gene="setB"
                     /locus_tag="ACHY1N_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HFS4042450.1"
                     /translation="MHNSPAVSSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPAMVGFFFSGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWN
                     RNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMQKELPLATGTIEAPRRNRRDT
                     LLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMGTAAGLEIPTMLIAGYFAK
                     RLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIGILGGIGMLYFQDLMP
                     GQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKDV
                     "
     gene            complement(98727..98981)
                     /gene="yeiW"
                     /locus_tag="ACHY1N_000087"
     CDS             complement(98727..98981)
                     /gene="yeiW"
                     /locus_tag="ACHY1N_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HFS4042451.1"
                     /translation="MKCRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKI
                     FTSPLRPKVCAGLQASAEMCGNSRQQAMTWLIDLEMLTAP"
     gene            99136..99708
                     /gene="yeiP"
                     /locus_tag="ACHY1N_000088"
     CDS             99136..99708
                     /gene="yeiP"
                     /locus_tag="ACHY1N_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA];
                     GO_process: GO:0043043 - peptide biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HFS4042452.1"
                     /translation="MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSPGEKIRIHIEERRYMGRAD"
     gene            99931..101397
                     /gene="yeiQ"
                     /locus_tag="ACHY1N_000089"
                     /pseudo
     CDS             99931..101397
                     /gene="yeiQ"
                     /locus_tag="ACHY1N_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416677.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
     gene            101515..102501
                     /gene="yeiR"
                     /locus_tag="ACHY1N_000090"
     CDS             101515..102501
                     /gene="yeiR"
                     /locus_tag="ACHY1N_000090"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding GTPase YeiR"
                     /protein_id="HFS4042453.1"
                     /translation="MTRTNLITGFLGSGKTTSILHLLAHKDPNEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDEKSASNENFRDQLAAADIIVANKSDRATPE
                     SEQALQRWWQQNGGDRQLIHSEHGKVDGHLLDLPRRNLAELPASAAHSHQHVVKKGLA
                     ALSLPEHQRWRRSLNSGQGYQACGWIFDADTVFDTIGILEWARLAPVERVKGVLRIPE
                     GLVRINRQGDDLHIETQNVAPPDSRIELISSSEADWNALQSALLKLRLATTA"
     gene            102540..103253
                     /gene="lpxT"
                     /locus_tag="ACHY1N_000091"
     CDS             102540..103253
                     /gene="lpxT"
                     /locus_tag="ACHY1N_000091"
                     /EC_number="2.7.4.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kdo(2)-lipid A phosphotransferase"
                     /protein_id="HFS4042454.1"
                     /translation="MIKNLPQIVLLNIVGLALFLSWYIPVNHGFWLPIDADIFYFFNQ
                     KLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLSFWLKENAPGRRRIVIMGLVMLLTA
                     VLLNQLGQALIPVKRASPTLTFTDINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAF
                     MWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDR
                     LITFFDKSLPGKNKHFQNK"
     gene            103665..104231
                     /gene="mepS"
                     /locus_tag="ACHY1N_000092"
     CDS             103665..104231
                     /gene="mepS"
                     /locus_tag="ACHY1N_000092"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HFS4042455.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVG
                     SETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTF
                     REQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHAST
                     SSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            104412..105968
                     /gene="pdeN"
                     /locus_tag="ACHY1N_000093"
     CDS             104412..105968
                     /gene="pdeN"
                     /locus_tag="ACHY1N_000093"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HFS4042456.1"
                     /translation="MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYD
                     TLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDK
                     KTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
                     VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIA
                     GIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQ
                     FYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFEL
                     IARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERD
                     MLKEQEATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTET
                     ITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPLPLDDFVR
                     WLKKPYTPQW"
     gene            106050..107864
                     /gene="yejA"
                     /locus_tag="ACHY1N_000094"
     CDS             106050..107864
                     /gene="yejA"
                     /locus_tag="ACHY1N_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311096.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4042457.1"
                     /translation="MIVRILLLFIALFTFGAQAQAIKESYAFAVLGEPRYAFNFNHFD
                     YVNPAAPKGGQITLSALGTFDNFNRYALRGNPGARTEQLYDTLFTTSDDEPGSYYPLI
                     AESARYADDYSWVEVAINPRARFHDGSPITARDVEFTFQKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKPGKEDMLSLFSLPVFPEKYWKDHKLSDPLATPPLASGPYRITSW
                     KMGQNIVYSRVKDYWAANLPVNRGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLRMEND
                     AKNWATRYTGKNFDKKYIIKDEQKNESAQDTRWLAFNIQRPVFSDRRVREAITLAFDF
                     EWMNKALFYNAWSRTNSYFQNTEYAARNYPDAAELVLLAPMKKDLPSEVFTQIYQPPV
                     SKGDGYDRDNLLKADKLLNEAGWVLKGQQRVNATTGQPLSFELLLPASSNSQWVLPFQ
                     HSLQRLGINMDIRKVDNSQITNRMRSRDYDMMPRVWRAMPWPSSDLQISWSSEYINST
                     YNAPGVQSPVIDSLINQIIAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMAEDRLAW
                     WDKFSQPAVRPVYSLGIDTWWYDVNKAAKLPSARQQGE"
     gene            107865..108959
                     /gene="yejB"
                     /locus_tag="ACHY1N_000095"
     CDS             107865..108959
                     /gene="yejB"
                     /locus_tag="ACHY1N_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HFS4042458.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GNAGVLPGAGGEGIRASHAQTGVGNISDSNYRGGRGLDPEVIAEITHRYGFDKPIHER
                     YFKMIWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     YNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWY
                     QKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNIVSDISYTLVDPRIDFEGR"
     gene            108959..109984
                     /gene="yejE"
                     /locus_tag="ACHY1N_000096"
     CDS             108959..109984
                     /gene="yejE"
                     /locus_tag="ACHY1N_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4042459.1"
                     /translation="MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIAND
                     KPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPWLKQRLENNGWVLWAPIRFGA
                     TSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL
                     AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILLSLLIFIGEAVRDA
                     FDPNKAV"
     gene            109986..111575
                     /gene="yejF"
                     /locus_tag="ACHY1N_000097"
     CDS             109986..111575
                     /gene="yejF"
                     /locus_tag="ACHY1N_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HFS4042460.1"
                     /translation="MTQTLLAIENLSVGFRHQQTVRTVVNDVSLQIEAGETLALVGES
                     GSGKSVTALSILRLLPSPPVEYLSGDIRFHGESLLHVSDQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQGELNMGMLFITHNLS
                     IVRKLAHRVAVMQNGRCVEQNYAATLFASPTHPYTQKLLNSEPSGDPVPLPEPASTLL
                     DVEQLQVAFPIRKGILKRIVDHNVVVKNISFTLRAGETLGLVGESGSGKSTTGLALLR
                     LINSQGSIIFDGQPLQNLNRRQLLPIRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSAAQREQQVIAVMHEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILD
                     EPTSSLDKTVQAQILTLLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQG
                     PCARVFATPQQEYTRQLLALS"
     gene            complement(111579..111923)
                     /gene="yejG"
                     /locus_tag="ACHY1N_000098"
     CDS             complement(111579..111923)
                     /gene="yejG"
                     /locus_tag="ACHY1N_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejG family protein"
                     /protein_id="HFS4042461.1"
                     /translation="MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVAL
                     KLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNYNPF"
     gene            complement(112256..113446)
                     /gene="bcr"
                     /locus_tag="ACHY1N_000099"
     CDS             complement(112256..113446)
                     /gene="bcr"
                     /locus_tag="ACHY1N_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Bcr"
                     /protein_id="HFS4042462.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTLVFAAAAVACALANTIDQLI
                     VMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILALAAILASAMIFFLIKETLPPERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVAPENFGYYFALNIVFLFVMTIFNSRFVRRI
                     GALNMFRSGLWIQFIMAAWMVISALLGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIAFCASSSILFCLYASR
                     PKKR"
     gene            complement(113474..114169)
                     /gene="rsuA"
                     /locus_tag="ACHY1N_000100"
     CDS             complement(113474..114169)
                     /gene="rsuA"
                     /locus_tag="ACHY1N_000100"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HFS4042463.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGEIVRNAAFKLLPE
                     HDVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAWKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKDL
                     TKPAVLEVITPTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGGITLDADLAPGE
                     YRPLTEEEIASVV"
     gene            114318..116078
                     /gene="radD"
                     /locus_tag="ACHY1N_000101"
     CDS             114318..116078
                     /gene="radD"
                     /locus_tag="ACHY1N_000101"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFS4042464.1"
                     /translation="MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAEL
                     ARLARGRVLVLAHVKELVAQNHAKYQALGLEADIFAAGLKRKESHGKVVFGSVQSVAR
                     NLDAFQGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGKGW
                     IYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQAQS
                     NGLFSEADLNRELKKQQRITPHIISQIMEFAEKRKGVMIFAATVEHAKEIVGLLPAED
                     AALITGDTPGAERDVLIEDFKAQRFRYLVNVAVLTTGFDAPHVDLIAILRPTESVSLY
                     QQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANT
                     FWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRE
                     CDTVLVDPDDMLKAALRLKDALVLRCSGMSLQHGHDEKGEWLKITYYDEDGADVSERF
                     RLQTPAQRTAFEQLFIRPHTRTPGIPLRWITAADILAQQALLRHPDFVVARMKGQYWQ
                     VREKVFDYEGRFRRAHELRG"
     gene            116203..116487
                     /gene="rplY"
                     /locus_tag="ACHY1N_000102"
     CDS             116203..116487
                     /gene="rplY"
                     /locus_tag="ACHY1N_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HFS4042465.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDH
                     DKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA"
     gene            complement(116626..117633)
                     /gene="yejK"
                     /locus_tag="ACHY1N_000103"
     CDS             complement(116626..117633)
                     /gene="yejK"
                     /locus_tag="ACHY1N_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009295 - nucleoid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HFS4042466.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELH
                     RVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGF
                     VLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADR
                     STLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     N"
     gene            117815..118042
                     /gene="yejL"
                     /locus_tag="ACHY1N_000104"
     CDS             117815..118042
                     /gene="yejL"
                     /locus_tag="ACHY1N_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HFS4042467.1"
                     /translation="MPQISRYSDEQVEQLLAELLNVLEKHKAPTDLSLMVLGNMVTNL
                     INTSIAPAQRQAIANSFARALQSSINEDKAH"
     gene            118062..119822
                     /gene="yejM"
                     /locus_tag="ACHY1N_000105"
     CDS             118062..119822
                     /gene="yejM"
                     /locus_tag="ACHY1N_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS biosynthesis-modulating metalloenzyme YejM"
                     /protein_id="HFS4042468.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWP
                     TTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKL
                     RSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITAL
                     NQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNR
                     WFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAG
                     RGIPLSEDEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTP
                     ASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDE
                     KPQLSLLLQVLTDEKRFIAN"
     gene            119897..119973
                     /locus_tag="ACHY1N_000106"
     tRNA            119897..119973
                     /locus_tag="ACHY1N_000106"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:119931..119933,aa:Pro,seq:ggg)
     gene            complement(120077..122668)
                     /gene="yejO"
                     /locus_tag="ACHY1N_000107"
                     /pseudo
     CDS             complement(120077..122668)
                     /gene="yejO"
                     /locus_tag="ACHY1N_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311108.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter YejO"
     gene            122988..123635
                     /gene="narP"
                     /locus_tag="ACHY1N_000108"
     CDS             122988..123635
                     /gene="narP"
                     /locus_tag="ACHY1N_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HFS4042469.1"
                     /translation="MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASA
                     IDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAG
                     ADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ"
     gene            complement(123670..124722)
                     /gene="ccmH"
                     /locus_tag="ACHY1N_000109"
     CDS             complement(123670..124722)
                     /gene="ccmH"
                     /locus_tag="ACHY1N_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis thiol:disulfide
                     oxidoreductase CcmH"
                     /protein_id="HFS4042470.1"
                     /translation="MRFLLGVLMLMISGSALATIDVLQFKDEAQEQQFRQLTEELRCP
                     KCQNNSIADSNSMIATDLRQKVYELMQEGKSKKEIVDYMVARYGNFVTYDPPLTPLTV
                     LLWVLPVVAIGIGGWVIYARSRRRVRVVPEAFPEQSVQEGKRAGYIVYLPGIVVALIV
                     AGVSYYQTGNYQQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKN
                     PGDIEGWIMLGRVGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSSDPNDNR
                     LGGELLRQLVRSDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIE
                     RSIAQAMQHLSPQESK"
     gene            complement(124719..125276)
                     /gene="dsbE"
                     /locus_tag="ACHY1N_000110"
     CDS             complement(124719..125276)
                     /gene="dsbE"
                     /locus_tag="ACHY1N_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HFS4042471.1"
                     /translation="MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKP
                     VPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVG
                     MNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHA
                     GDLNPRVWEEEIKPLWEKYSKEAAQ"
     gene            complement(125273..127216)
                     /gene="ccmF"
                     /locus_tag="ACHY1N_000111"
     CDS             complement(125273..127216)
                     /gene="ccmF"
                     /locus_tag="ACHY1N_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis heme lyase CcmF"
                     /protein_id="HFS4042472.1"
                     /translation="MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAW
                     LLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLCGRLDSTYARFTRPWTLAAWIF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWT
                     LLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARG
                     HKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVA
                     MTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYS
                     VERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRY
                     YNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGG
                     LLCLFDPRYRKRVSPQKTAPEAV"
     gene            complement(127213..127692)
                     /gene="ccmE"
                     /locus_tag="ACHY1N_000112"
     CDS             complement(127213..127692)
                     /gene="ccmE"
                     /locus_tag="ACHY1N_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HFS4042473.1"
                     /translation="MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEIL
                     YGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDL
                     FREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS"
     gene            complement(127689..127898)
                     /gene="ccmD"
                     /locus_tag="ACHY1N_000113"
     CDS             complement(127689..127898)
                     /gene="ccmD"
                     /locus_tag="ACHY1N_000113"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015886 - heme transport [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HFS4042474.1"
                     /translation="MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHR
                     AILRGVAQQRAREARLRAAQQQEAA"
     gene            complement(127895..128632)
                     /gene="ccmC"
                     /locus_tag="ACHY1N_000114"
     CDS             complement(127895..128632)
                     /gene="ccmC"
                     /locus_tag="ACHY1N_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmC"
                     /protein_id="HFS4042475.1"
                     /translation="MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFA
                     PADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAV
                     FTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAG
                     ILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSIFGFLLLSATLTL
                     MRMRNLILLMEKRRPWVSELILKRGRK"
     gene            complement(128674..129336)
                     /gene="ccmB"
                     /locus_tag="ACHY1N_000115"
     CDS             complement(128674..129336)
                     /gene="ccmB"
                     /locus_tag="ACHY1N_000115"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015232 - heme transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015886 - heme transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HFS4042476.1"
                     /translation="MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQ
                     LLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWM
                     VTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
                     LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRIS
                     IQ"
     gene            complement(129333..129956)
                     /gene="ccmA"
                     /locus_tag="ACHY1N_000116"
     CDS             complement(129333..129956)
                     /gene="ccmA"
                     /locus_tag="ACHY1N_000116"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HFS4042477.1"
                     /translation="MGMLEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTT
                     LLRLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHR
                     DGDTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAID
                     VNGVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRAA"
     gene            complement(129969..130571)
                     /gene="napC"
                     /locus_tag="ACHY1N_000117"
     CDS             complement(129969..130571)
                     /gene="napC"
                     /locus_tag="ACHY1N_000117"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HFS4042478.1"
                     /translation="MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYQEYMDSVHYNNRSGVRATCPDCHVPHEFVPKMIR
                     KLKASKELYGKIFGVIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTA
                     QKSVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMREVEPGF"
     gene            complement(130581..131030)
                     /gene="napB"
                     /locus_tag="ACHY1N_000118"
     CDS             complement(130581..131030)
                     /gene="napB"
                     /locus_tag="ACHY1N_000118"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HFS4042479.1"
                     /translation="MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQE
                     GAIRMPKEQERMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK"
     gene            complement(131027..131890)
                     /gene="napH"
                     /locus_tag="ACHY1N_000119"
     CDS             complement(131027..131890)
                     /gene="napH"
                     /locus_tag="ACHY1N_000119"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HFS4042480.1"
                     /translation="MANRKRDAGREALEKKGWWRSHRWLVLRRLCQFFVLGMFLSGPW
                     FGVWILHGNYSSSLLFDTVPLTDPLMTLQSLASGHLPATVALTGAVIITVLYALAGKR
                     LFCSWVCPLNPITDLANWLRRRFDLNQSATIPRHIRYVLLVVILLGSALTGTLIWEWI
                     NPVSLMGRSLVMGFGSGALLILALFLFDLLVVEHGWCGHICPVGALYGVLGSKGVITV
                     AATDRQKCNRCMDCFHVCPEPHVLRAPVLDEQSPVQVTSRDCMTCGRCVDVCSEDVFT
                     ITTRWSSGAKS"
     gene            complement(131877..132572)
                     /gene="napG"
                     /locus_tag="ACHY1N_000120"
     CDS             complement(131877..132572)
                     /gene="napG"
                     /locus_tag="ACHY1N_000120"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HFS4042481.1"
                     /translation="MSRSAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARASGV
                     RLRPPGAINENAFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALDREIESIDDARMGLAVLVDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELERNTRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGNNGKS"
     gene            complement(132579..135065)
                     /gene="napA"
                     /locus_tag="ACHY1N_000121"
     CDS             complement(132579..135065)
                     /gene="napA"
                     /locus_tag="ACHY1N_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009325 - nitrate reductase complex
                     [Evidence IEA];
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_process: GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic nitrate reductase subunit alpha"
                     /protein_id="HFS4042482.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLL
                     RMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAAS
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAE
                     MHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYII
                     QNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVA
                     EYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPS
                     GTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVS
                     DPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNKLTLDATDPLSKETDFKKCAVKLEKV"
     gene            complement(135062..135325)
                     /gene="napD"
                     /locus_tag="ACHY1N_000122"
     CDS             complement(135062..135325)
                     /gene="napD"
                     /locus_tag="ACHY1N_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HFS4042483.1"
                     /translation="MHTNWQVCSLVVQAKSERISDISTQLNAFPGCEVAVSDAPSGQL
                     IVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQEEQGEETP"
     gene            complement(135315..135809)
                     /gene="napF"
                     /locus_tag="ACHY1N_000123"
     CDS             complement(135315..135809)
                     /gene="napF"
                     /locus_tag="ACHY1N_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HFS4042484.1"
                     /translation="MKIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACI
                     NACENNILQRGAGGYPSVNFKNNECSFCYACAQACPESLFSPRHTRAWDWQFTIGDAC
                     LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEY
                     LHAH"
     gene            135918..136082
                     /gene="yojO"
                     /locus_tag="ACHY1N_000124"
     CDS             135918..136082
                     /gene="yojO"
                     /locus_tag="ACHY1N_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YojO"
                     /protein_id="HFS4042485.1"
                     /translation="MHTPIGVKPVAGSKEWREAWQKRAFAHISNGYKYIYIAINSPEI
                     FLLVCSLIRI"
     gene            136196..136705
                     /gene="eco"
                     /locus_tag="ACHY1N_000125"
     CDS             136196..136705
                     /gene="eco"
                     /locus_tag="ACHY1N_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004867 - serine-type endopeptidase
                     inhibitor activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HFS4042486.1"
                     /translation="MKKESKKMKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAE
                     KGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENKTLEGWGYDYYVFD
                     KVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAE
                     EKIDNAVVR"
     gene            complement(136854..138500)
                     /gene="mqo"
                     /locus_tag="ACHY1N_000126"
     CDS             complement(136854..138500)
                     /gene="mqo"
                     /locus_tag="ACHY1N_000126"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008924 - L-malate dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HFS4042487.1"
                     /translation="MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSA
                     TLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISI
                     EKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
                     QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIAS
                     LQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLL
                     QESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLD
                     GKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVML
                     SEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDADKGGVLRLGTEVVSDQQGTIA
                     ALLGASPGASTAAPIMLDLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERE
                     LQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL"
     gene            complement(138718..140361)
                     /gene="yojI"
                     /locus_tag="ACHY1N_000127"
     CDS             complement(138718..140361)
                     /gene="yojI"
                     /locus_tag="ACHY1N_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin J25 efflux ABC transporter YojI"
                     /protein_id="HFS4042488.1"
                     /translation="MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETA
                     DTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTNVERIEQL
                     GSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAIT
                     IWGGFVLVARVYKHMATLRETEDRLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDA
                     QEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFAYQD
                     NAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQP
                     EDYRKLFSAVFTDVWLFDQLLGPEGKPANPQLVEKWLAQLKMAHKLELSNGRIVNLKL
                     SKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA"
     gene            complement(140437..141087)
                     /gene="alkB"
                     /locus_tag="ACHY1N_000128"
     CDS             complement(140437..141087)
                     /gene="alkB"
                     /locus_tag="ACHY1N_000128"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HFS4042489.1"
                     /translation="MLDLFADAEPWQEPLAAGAVILRRFAFNAAEQLIRDINDVASQS
                     PFRQMVTPGGYTMSVAMTNCGHLGWTSHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQR
                     AATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLK
                     RNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTTDCRYNLTFRQAGKKE"
     gene            complement(141087..142151)
                     /gene="ada"
                     /locus_tag="ACHY1N_000129"
     CDS             complement(141087..142151)
                     /gene="ada"
                     /locus_tag="ACHY1N_000129"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HFS4042490.1"
                     /translation="MKKATCLTDDQCWQSVLARDPNADGEFVFAVRTTGIFCRPSCRA
                     RHALRENVSFYANASEALAAGFRPCKRCQPEKANAQQHRLDKITHACRLLEQETPVTL
                     EALADQVVMSPFHLHRLFKATTGMTPKAWQQAWRARRLRESLAKGESVTTSILNAGFP
                     DSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCELGRSLVAESERGICAILLGDD
                     DATLISELQQMFPAADNAPADLMFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVW
                     QALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIIIPCHRVVRGDGTLSGY
                     RWGVSRKAQLLRREAENEER"
     gene            complement(142225..143280)
                     /gene="apbE"
                     /locus_tag="ACHY1N_000130"
     CDS             complement(142225..143280)
                     /gene="apbE"
                     /locus_tag="ACHY1N_000130"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HFS4042491.1"
                     /translation="MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGT
                     FWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSTLMRFNDSQSLSPWPVSEA
                     MADIVTTSLRIGARTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQH
                     LTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALDSR
                     GMNGEGQPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQ
                     TGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRREGLAVYMITKEGDSF
                     KTWMSPQFKSFLISEKN"
     gene            complement(143392..144495)
                     /gene="ompC"
                     /locus_tag="ACHY1N_000131"
     CDS             complement(143392..144495)
                     /gene="ompC"
                     /locus_tag="ACHY1N_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HFS4042492.1"
                     /translation="MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNKDVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLK
                     FQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
                     VDGLNFAVQYQGKNGSVSGEGMTNNGRGALRQNGDGVGGSITYDYEGFGIGGAISSSK
                     RTDDQNSPLYIGNGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNF
                     EAVAQYQFDFGLRPSVAYLQSKGKNLGTIAGRNYDDEDILKYVDVGATYYFNKNMSTY
                     VDYKINLLDDNQFTRDAGINTDNIVALGLVYQF"
BASE COUNT        35814 a        38210 c        35355 g        35324 t
ORIGIN      
        1 tccgtataaa tacatttgat aacgctgtat gactatctga gagcttaaag atttttgccg
       61 tgtccatttt attcagccct gtaagttgct tatgatggat tgcccagacc caaccacatt
      121 aaccaccctt ccctaatttc cttgggacga ctctcatacg ccattttcat tccgttgttc
      181 caggctggga ggtagaccca gtactcacct gcccgccctg aagttgattg cggatcagtc
      241 atctcaacta cgggtagctt tcctttttca atcattcccc ttactgctgc cggtgttttg
      301 ccgatcagtt ttgcaaactc ctggtacggg acagcatcac taatactgac aacttgtttg
      361 ctcatctgct aacctcgtat ctagatctaa ccaatgggtt tcaaagttct ttaatgggct
      421 ttgatgcaca ttgacaacat ctaaaaccac attagagagt ttcgataata ttagaggatc
      481 ttgataacat gtcaacgccc ataagcgaaa aactagcgtt agttcgtgag tctgagcgac
      541 taaaccggaa gcaattcgct gaaataacag gagttcctta cagttctcta acttattatg
      601 agagcggaag aactacgccc cccactgacg taacaatgaa aattctccag caccccagat
      661 ttagcaaata cacgttgtgg tttatgaccg atcaggttgc tcccgaagcc ggtcagatag
      721 caccggccct cgcacacttt gggcaagatg taacaacatc gcagcactca gaccaaaaga
      781 ttggttaacc attcaccagg cgcatcttta ttacaaaatt tgtttacttg ttgccaaata
      841 caacaagcac aacaagtttg tgaaatctaa gcgcaaggga aaattaacag cagcaaagaa
      901 aacacaacct agcaccattc atttgggggt cttatgacaa ttaagaaact cgatgatggt
      961 cgttatgaag tggacatcag acctgcaggg cgcaacggaa agcgcatccg caggaaattt
     1021 gacaagaaaa gtgaggctgt agcttttgag aaacacactc aatacaacca tcacgataaa
     1081 gaatggttgg ctaaaccgac agataagcgg catctgtctg aattaacgaa agtctggtgg
     1141 gatctgaaag gcaagcatga agaacacgga aaatctaatt tgggtaagat tgaaatcttt
     1201 acccggatca ctgatgaccc ttgcgcgttc cagataacca aagcgcttat tagccagtac
     1261 agcatgactc gcagagggca aggcataaaa ccggccagta ttaaccgcga tcttacctgc
     1321 ctgagtggta tgtttactgc gctaattgat gcggaattgt tctttggtga acatcctttc
     1381 agagggatga aaaagctcaa ggagcagaaa ccagaaaccg gctatctgac gcaggaagaa
     1441 ataacattgt tgcttgccaa tcttgacggg gacaacaaga aaatcgcgat tctctgttta
     1501 agtaccggcg ctcgatgggg tgaggccgcg aaactgaaag ctgagaacgt aatacagaat
     1561 cgggtgacgt tcgttaaaac aaagacgaac aaaccgcgta ctgtccctat ctctgaggaa
     1621 gtggctgtaa tgattgcggg taaaggttat ctgttccctg atgcctcata cccgaagttc
     1681 aggcgaacaa tgaaagatgt aaaaccagat ctaccggacg ggcaagcaac tcacgcattg
     1741 cgtcacagtt ttgctaccca ctttatgatt aacggcggga gtatcatcac cttgcagaga
     1801 atactgggac attcacggat agagcagaca atggtttatg cgcactttgc cccggagtat
     1861 cttcaggatg ctgtttcact caatccgcta cgtggtggtg ttgactccca gagtgtccac
     1921 actgtgtcca cagtagggta gtttattatg gctttcagtg gtcttgcgtg ccgcacaaac
     1981 ccgcattgca ccgctgaaag cccatgttac ctaccctgaa aaacgccctt acacgggctt
     2041 attttttatg cataagccct atccctggtc accgtcttcc attgaccaca tcgatagaat
     2101 ctcccttcat agcacgatgc ctttcacgta acggcatcgt gctcgcacag gttccggcta
     2161 agcacaacca gaacgcgcat gtttgacgct taccaaaaaa tattctcact ctccacattt
     2221 gaatgtcaga cgagcgacgc catgtaatcc tgcaccttct gtcttcaggt caactatctg
     2281 catttttttg ccctgagtaa cacagaaatg ggctgcatca ttttttacta tattttctgc
     2341 accagatatt ctgcccctgg ctaaagaagc ttcggcttcg gtgtagtatt ggttatcgag
     2401 tttacgctga atattacttt tatatgcaag accaaattta ccgatacttg tctcatcatt
     2461 atgcacagca caaccagaca taataaaaat actaattaat gatatagcag ctatcttttt
     2521 catctcacct tcccccatta aataccaacg acactctcta gtgtttaaat ataataatgg
     2581 catgattatt ataattgaat aggattataa taaatgttct gtacaacatt tcctacataa
     2641 gtaggaatta cggacattga ggcccttcag ggtaactcca tgggggcttt aatatatttg
     2701 gaatagtata tttaagatgc cactgtttgg ttgaatatta ggcatatgct cttttttgaa
     2761 atttatcggt ggcagccgtt agtattcgct gtccccattg caagctcctg gtggtaacca
     2821 ctgaatcctc catacttgaa ctgacttttt atcctccgac tttcatcctg ttctgactcc
     2881 accttttgtt ttctgctcta cactatctac agaccaatca taaaggcaca tacgatcatg
     2941 gcagaatttc ccgccagctt actgattctt aatggcaaaa gtactgacaa tctacccttg
     3001 cgcgaagcaa ttatgctgtt gcgtgaggaa ggaatgacga tccatgtgcg ggtcacctgg
     3061 gagaaaggcg atgccgcacg atatgtagag gaggcccgga agttgggcgt cgcaacggtg
     3121 attgccggtg gtggcgatgg caccattaat gaagtttcta cggcgttgat tcagtgtgag
     3181 ggggatgaca tacccgcgct gggaattttg ccattaggaa ccgccaatga ttttgccacc
     3241 agtgtaggga ttcctgaggc actggataag gcgctgaaac tggcaattgc cggtaacgcc
     3301 attgcgatag atatggcgca ggtcaacaaa caaacctgtt ttattaatat ggcgacaggc
     3361 ggatttggga cgcgtattac cacagaaacg ccggaaaaat taaaagccgc gctgggtggc
     3421 gtctcttaca tcattcatgg cttaatgcgc atggatactc tgcaaccgga ccgttgtgaa
     3481 atccgcggtg aaaactttca ctggcaaggt gacgccctgg tcattggtat tggtaacggg
     3541 cgtcaggccg gtggcggtca gcaattgtgt ccgaacgcgt taattaacga tggcttgctg
     3601 caactgcgca tttttaccgg cgatgaaatt cttccggctc tcgtatcaac cttaaaatct
     3661 gacgaagata acccgaatat tatcgaaggc gcttcgtcgt ggtttgatat acaagcccca
     3721 cacgaaatca cttttaatct tgatggcgaa ccgttgagcg gacaaaactt tcatattgaa
     3781 atacttccgg cggcgttgcg ttgtcgatta ccaccagatt gtccattatt gcgttaatca
     3841 aactattctc tcttgaacca gggagaatcc gaaatgccgg atgcggtgta aataccttat
     3901 ccggcataca gaacaatact acaccgtaat taattttacc cgtgtcttct gcaatgccag
     3961 tttatccacc tctgatacag catcatcggt aataataatg tcaatttttt cgattggcag
     4021 tacctgatta aaaccgcgac ggttaaattt cgatgaatcg agaacggcaa tcactttatt
     4081 agcggcggtg accatcgcac cgctaatcga ataaccttca ttaaaggtcg taataccatt
     4141 aaccgcatca ataccatcag caccgacaaa cattaaatcg gcattaatat cctgcaggga
     4201 acgttcagca atagatccat gcatagatcg cgttttatgg cggaccgtgc caccgcagac
     4261 gaccagagta atgtctttat tttcggaaag ggcaaacgca gccgggagac tgttggtaat
     4321 caccgtgata tttttggcgg tcattaatcc ttcggcgata agcattgtgg tacttccgct
     4381 gtcgagaata acggtcatcc cttcatggat cattttgact gccgcctgcg ctattctgtt
     4441 tttcggcgcg ctggcgagct gaaatcgctc tttaaacccg acttcctggg tctcggtttc
     4501 actattaccg gacattattt tcgccgcacc gccatgaaag cgcgtaacca cgcctttttg
     4561 ttcgagaaag cgcaaatcgg cacggattgt cgcttccgag gcagcaaata ctcccgccag
     4621 atcctgaaca agcacggttc cctgttcatt cactaattgg atgatcttat tccttcgctc
     4681 gaatgaattc atcgtcattt acccatattc aattgtggct agtgtaaacg aagggggacc
     4741 attggtgaat gatctgtttt gcacaatacc gggccagcat cacgctggcc cgcggtttca
     4801 gggaatgagc aacactttgc ccggcatagc attacgagcg atgtcacgca ccgcctgggc
     4861 gaagctttca aagcttccac ggtgagcgat taatggctcc aggcttaact tacgttctgt
     4921 cagcaaccgg ctcgccgttt cccactcctg ccccggccaa gggctggagt agttcatcca
     4981 actgccgata accgtcagct ctttacgcaa tattttgcca aacgttgccg atgttaaatg
     5041 cagatcctga tgcaacgtgc ccaccagcgc cagttgggca tgaggaccgg caatctctac
     5101 cgccagttcg acagtttgcg gtacgccagc cgtctcgagg ataagctgat taaagcgcag
     5161 ttcgcgtaaa acgctctgca tttgcggcgc gctcatttcg ctactgttaa atgtttgcat
     5221 cgcaccgaaa gattttgcca gtgccagttt ttctgaacta atgtcgatcg ccgtcacact
     5281 ctttgctccc agcgcgacag cgcactgaat ggccagcagg ccaatggttc cggcaccaat
     5341 aataataacg tttttattct cacaaccttg cgctaaatga aaagcatgca ggccaacggt
     5401 aatcggttca ataaaagccc catcctcaat aggcatatca gtaggtagag caaagacatt
     5461 tttccgctta acgacaatat attcggcaaa tccaccatca cgccgtgagc caataaaatc
     5521 atattttgcg cactgggaat aaaacccttt caaacactct ggacaagtaa aacagggtaa
     5581 taacggcaca caggcaaccg catcgccagg atgtaaatca tcaacaccgg atcccaccgc
     5641 atcaatatag ccgctaaatt catggcctaa cgttattgga taataatgtg caccattttt
     5701 aaatatcctg ggtaaatcgg aaccacataa gcccgagctg gcaattttta cccgcacctc
     5761 atcctgatgt ttaatttcag gaatgacgct ttctgcaacg cgcacgatac catcagtatc
     5821 attcaccact gatttcataa aaactcctga ttgttaaggg ggataacctc cccctcaggt
     5881 aaaaattatt ctgcgagaac gactttctct tgtttaataa agccacgcgc tctacgccag
     5941 gtcatgaaaa taccggtaag ataaattgcg ccgataataa tgaatccggg aatattttgc
     6001 ggggagaaaa cctgaatcag taaccaggta atgggagaac cgccctgatc cattgaagcc
     6061 accatacccc cggcttttaa cgccccagca ttagccgcca gttgggtgtg caaaccaata
     6121 gtttgcgtcg cgatccacag agtgatgctc atgatgatga cacccgagat taaggtgcgg
     6181 aacagatttc cacgatgcac ggcgactgcc atcgccacaa agaagccgat ggtggcaaga
     6241 tcgccaaacg gcagcacctg attacccgga acacaaacag caattaaaat ggtgagcggg
     6301 ataaaaatca ggcttgccga taccaccgcc gtatgcccca gcagtaatgc gggatccagg
     6361 ccaatcagga actcctgacc gccgaacttc gcctgtaaac gactacgggc ctgcttagcg
     6421 atgggcgtta aaccatccat gatgggttta atcacccgtg gcattagcag catcactgcc
     6481 gccgttttta ccgccagctg caatacacct ttgacatcgt aacccgcgag gatgccgata
     6541 atcagcccca tcacaaaacc cacggtgaca ggctcgccaa atggaccaaa tttgcgctga
     6601 atatcgtcgg cgctaaattt aattcggtta acgcctggga ttttctcgat gatagcatcg
     6661 accagcaccg caatcggccc catatacgcc gacgtaccgt gcggaatagc aataccttcc
     6721 agctcaaaga aatttcgggt atcgcgggca aaccagtcgc cgagcttata aacaaacgcc
     6781 gcgtgaatta ccacacctgc catccctatc atccatgaac cggttgccag gtgcagcaac
     6841 gcgccggtga aggtcatatg ccagatattc cagatatcaa catttaccac ccgcgtcata
     6901 cgggtcagta acatcgccac gttaaccaat atcgcaatcg gaatcgccac cagcgcaatt
     6961 tgcgacgccc aggtcattgg tgaagagccc ggccagccga catcgaccac atgcagattc
     7021 aggtcgaaat tttccgccat cgctttcgcc gccggaccaa tggaatccag cattaagcca
     7081 atcacaaggc caatgccaac aaagccaatc ccgatatgca gacccgcttt aaagcaatcg
     7141 cctgccttca tgcctaatat tttagaaaaa ataatgatga caaccggcag catcactgta
     7201 gggccgaggt cgagaatata acgcatgact tctgaaaaca taggtcaccc ctgtaagata
     7261 gtcagaattt tattttgtaa tgcttcgata ccgacaccag aaacaaaagg catgccgtga
     7321 actaacggaa tatcgccaaa actgcgatcc cccctggcag tggtacatat caaatgcaca
     7381 ccatccatat aggtttctat ttcattaacc cgacactgga ttaattcaac aggaatatta
     7441 tgactctgac acaactcttt aatttcttcc gccgccatcg tagaggtcgc aaccgcgcct
     7501 ccgcaagcga caataatctt gcgtttcata aatagtcctt tttattgtta cagagggatt
     7561 tattcgtctg aatctaaaac atactttgtg aagtattcct ttaactgggt ttcaggaaga
     7621 gtgattagtg tctcgacgat atcgggctgt tgtaacttgc caaataaaca gcgtaaaagt
     7681 ttcaattgct gctgcggatt ttccacaatc aacgcaataa ccaacgatac cgccacgtcg
     7741 ttatcatcat ccgcttgctg aaaatgaact ttatttgttg gccttaacag ataaatggct
     7801 gacgacttag catgaatcgc ctcacaatgc ggtattgcaa tggcgtgctg ctcaagcatt
     7861 atcccggtag ggaattctgc ttctctggca attaatgcct gtggccaggt atcatgaacc
     7921 acacctttgg cgagcatctc attaccgata tgggttaaaa cttcgctacg atcgacaaaa
     7981 gaaattccgc tacgaacaaa caggttagtc atataccgtc cttattccgc acagccgtag
     8041 cgataggcgc gcaaaacatc ataaatttta tccataatca gctgatgcgg tattgctgat
     8101 aattccccgg actgaatgcg ttcaaattgt ttgggaagat actgactaat catgcccagt
     8161 gggatgtcca cgccttcaag attcaccatc atcgtttcga cgctattttt aatccgacta
     8221 tgcggccagt aataacgaat acgatccgac aggctgtaac gaatatccag taatgaatcg
     8281 ttaaaacccg tacgataata ttttttccag tattgcggtt cgtcgagcat cacttcttca
     8341 attaccgcca ggcaaccgct gcgattttca ggggcgataa gttcctgctc aatttgtgcc
     8401 agtgcaaata tcgcctcgcg taaagcaaag gttaatgcgg gaccgacttt caatattgca
     8461 aagtgatcgc ggactaattc ccaataagcc gtccgggtct ggtaatcggt agaatgtgct
     8521 tcataaacca ttcgggtgtt ttctatccat tgcgccagcg gctgcgcttc ctgcggctga
     8581 taatggataa tattgctgtg atcaaattcc acgcccggct gcaccacgat ggcaatcacg
     8641 cgtgttaacg cctctgtcag cccacgggca ataaaggcct tttgatgcgt acgtaaagta
     8701 ttggcggtat cttcaacatg ggtgatgtgt actgactgaa tggcgctggc ctcaccgccc
     8761 ggaaccggaa cttcggtgcc aatgacatag ctcagttgct cacgctggca atctgtcgcc
     8821 acactttccg cagcaaagca aagcacagca gctcgttccg caaccgtttc tggtgctaac
     8881 ggtatgggat cccccgcgca ggacattgac gcatcaagat gaattttact gaagccggca
     8941 cgaacatatt cctttaccag ctcgacggat ttttccatcg ccgcatccgc attttcttgc
     9001 tgccagcagt ttggccccag atgatcgccg ccgagaataa tgcgttcgcg tgcaaaccca
     9061 actttatcgg caatcgtaaa aacaaattcg cgaaagtctg ccggtgtcat tccggtataa
     9121 ccgccaaatt gattgacctg gtttgacgtt gcttcaatca gcactttgcg cgtgctgttg
     9181 cgatcaaatg ccagcgccgc ttcgataacc aacggatggg cagaacagac tgaacatatg
     9241 ccgatatgtt caccagcttt atgccgggca attaacgttt tcatgttttt tccttattaa
     9301 atggcaggtg cgttatgccc tgccctagca gccacaatcg gcaatcactt tgctcaccac
     9361 atcgcgcatt gcggatttag ccgactgcaa ataatcccgg ggatcggtcg cttcagggtg
     9421 ctcggtcagg taatttttta acgcctgcga gaaggcattt ttcagctccg ttgcaacgtt
     9481 gattttgcat atccccagtt tgatggtttg ctgaatatcc ttagtcgata accctgacgc
     9541 gccatgcagc accagcggta agttcaccca ctggcgaatg ttctccagtc gagaaaaatc
     9601 aagcgccggt gcgctggcat acatcccatg agccgtgccg atggcgaccg ccagggaatc
     9661 aattccggtt gcctcggcaa attcacgcgc ctgagcgggg ttggtataaa aagcatcggc
     9721 ttcattgact tgcacatcat cttcctggcc gccaagttgc cccagctccg cttcgacgct
     9781 gacatcaaag cgatggcaaa aatccaccac ctctttgacc cgtgaaatat tttgcgcaaa
     9841 aggcaaatgc gaggcgtcaa tcatgactga gcgcacgcca gaacgaacct tctgagcgat
     9901 atcgtcaaat ttcgtgtgat ggtcgagatg aattgccagt ggatggtgat attgcttcgc
     9961 catcgcgctg accagcgcca acagattttc tgtaccagca tgagtaaatg tgccaggcgt
    10021 tccggcgatg atgaccggcg catgcaggtt ggcagcggtt tccaccacca cttgcatcgt
    10081 ttcgagattg tgaatattga atgccggaac cgcataaccg ccgcgctgtg cgttgttcag
    10141 catctgcttt gtcgatacca cgtacatttt catatcctgt cgtttgtttt cgatttcaaa
    10201 atataatgaa atgatttgtt tttaaatgtc gagataacga tcacaaaaac gacaatgtga
    10261 aaattgttcg aggagtaaaa ggcaaaaaaa aacggcctcc cgatagggaa gccgtagcaa
    10321 agtgcgcgtg tttttatgcc ggatgcggtg taaacatacg tggcagtgct atgtaggcat
    10381 gataagacgc ttccgcgtcg catcaggcat aggttgccgg atgcagtgta aacgccttat
    10441 ccgtcctacg gggtggtgct gttcgtatga ggcgtatcag gcaatagtaa ttttgctatc
    10501 gagataaacg tcctgcacgg cattaatcag tttcacgccg tcagccatcg atttcttgaa
    10561 cgccttacgt ccaagaatca gccccattcc gccagcgcgt ttgttgataa ccgcagtacg
    10621 cactgcatca ctgaggtcag tttcaccgcc tgcagcaccg ccggagttaa tcagccctgc
    10681 gcgccccata tagcagttag ctaactgata acgcaccaga tcaatcgggt tttcgctggt
    10741 taacttgctg tacacgcgat cgtcggtata accgtaatta attgctttat agccgccgtt
    10801 attttccgcc attttttgtt tgacgatatc tgcaccgatg gttgccgcca gatggtttgc
    10861 ctgaccggtc aggtcggcgg aaacatggta atcaacgcca tctttcttaa aggcggagtt
    10921 acgcaaatag gcccacagca ctgtcaccat acccagctcg tgcgcacgtt caaaagccgc
    10981 agaaatttct tcaatctggc gacgtgactc ttccgagcca aaatagatag tcgcaccaac
    11041 cgcaaccgcg cccatgttga acgcctgctc cacgctggca tacagcgttt gatcgtaggt
    11101 attcgggtaa cttagcgtct cgttgtgatt aagtttgacg aggaatggaa tgcgatgcgc
    11161 ataacgccgc gataccgacg ccagcacgcc gtaagttgac gccacacagt tacagcccgc
    11221 ttcgatcgcc agttcaacaa tgtttttcgg gtcaaagtag agcgggttag cagcaaatga
    11281 agctccggca gagtgctcaa cgccctggtc aaccggcaga atagaaagat atcctgtgcc
    11341 agccagacgc ccggtgttgt acaacgtctg catattacgt aacaccgctg gcgggcgatt
    11401 attgtcaatc attacgcggt ctacgtagtc atgtccgggg agataaagct ggtcagaagg
    11461 aattgtcata caacggtgct gtaaaaggtt gtcggcgtct ttgccaagca actgcgcaat
    11521 atctgtcatt actatgctcc cgtaaattcc gattggatat cggctatgga ttgtcctggc
    11581 ccgccttttg cgggcaatca taatcctggt cgttacgggc gagtttttcc atcttttgga
    11641 tgttttttca gcgttttctg ttggctcgat tcatcagaaa aaatgttagc gcggtcaagt
    11701 tttcaccgca aaggtattta aaaggtatta ttaagtggta ttatcatcgc gtaccttaca
    11761 ttacctgtca tgaaggaatt aaaagatgaa aacaacagca aagctgtcgt tcatgatgtt
    11821 tgttgaatgg tttatctggg gcgcgtggtt tgtgccattg tggttgtggt taagtaaaag
    11881 cggttttagt gccggagaaa ttggctggtc gtatgcctgt accgccattg cggcgatcct
    11941 gtcgccaatt ctggttggct ccatcactga ccgctttttc tcggcgcaaa aagtgctggc
    12001 ggtattgatg ttcgcaggcg cgctgctgat gtatttcgct gcgcaacaga ccacttttgc
    12061 cgggttcttt ccgttactgc tggcttactc tctaacctat atgccgacca ttgcgctgac
    12121 taacagcatc gcttttgcca acgtgccgga tgtggagcgt gatttcccgc gcattcgtgt
    12181 gatgggcact atcggctgga ttgcctccgg tctggcatgt ggtttcttgc cgcaaatact
    12241 ggggtatgcc gatatctcac cgactaacat cccgctgctg attaccgccg gaagttctgc
    12301 tctgctcggt gtgtttgcgt ttttcctgcc cgacacgcca ccaaaaagca ccggcaaaat
    12361 ggatattaaa gtcatgctcg gcctggatgc gctgatcctg ctgcgcgata aaaacttcct
    12421 cgtctttttc ttctgttcat tcctgtttgc gatgccactg gcgttctatt acatctttgc
    12481 caacggttat ctgaccgaag tcggcatgaa aaatgccacc ggctggatga cgctcggcca
    12541 gttctctgaa atcttcttta tgctggcatt gccgtttttc actaaacgct ttggtatcaa
    12601 aaaggtatta ttgcttggtc tggtcaccgc tgcgatccgc tatggcttct ttatttacgg
    12661 tagtgcggat gaatatttca cctacgcgtt actgttcctc ggtattttgc ttcacggcgt
    12721 aagttacgat ttttactacg ttaccgctta catctatgtc gataaaaaag cccccgtgca
    12781 tatgcgtacc gccgcgcagg ggctgatcac gctctgctgc cagggcttcg gcagtttgct
    12841 cggctatcgt cttggcggtg tgatgatgga aaagatgttc gcttatccgg aaccggtaaa
    12901 cgggctgact ttcaactggt ccgggatgtg gactttcggc gcggtgatga ttgccattat
    12961 cgccgtgctg ttcatgattt ttttccgcga atccgacaac gaaattacgg ctatcaaggt
    13021 cgatgatcgc gatattgcgt tgacacaagg ggaagttaaa tgaaaacaga acgtattctc
    13081 ggtgctcttt atgggcaggc gttaggggat gcgatgggga tgccctccga gctttggcca
    13141 cgcagccgcg ttaaagcaca ctttggctgg attgaccgtt ttctgcctgg accaaaggag
    13201 aataacgcgg cctgttattt taaccgcgcc gaattcaccg acgatacctc gatggcgctg
    13261 tgtctggcgg atgcgttact ggaacgtgaa ggcaagatcg atccggatct gattgggcgt
    13321 aatattctcg actgggcgct gcgtttcgac gcctttaaca aaaacgtact aggtccgacc
    13381 tcgaagattg cgcttaacgc cattcgcgac ggtaaacccg ttgctgaact ggaaaacaac
    13441 ggcgtgacca acggcgcagc gatgcgcgtc tcgccattag gttgtttgct tccggcgcgt
    13501 gatgttgatt cctttattga tgatgtggcg ctggcgtcga gcccgaccca taaatccgat
    13561 ctggcagttg caggtgcggt agtcatcgca tgggcgattt ctcgtgccat tgacggagaa
    13621 agctggtcag cgattgttga ttccctgcct tcaattgcgc gacatgcaca gcaaaaacgc
    13681 atcactacct tcagcgcctc actggcagca cgtctggaga ttgcgctgaa aattgtgcgc
    13741 aatgccgacg gcaccgaatc cgccagcgaa cagctttacc aggtcgttgg cgcaggtacc
    13801 agcactattg agtccgttcc gtgcgccatt gcgctggttg aactggcaca aaccgacccg
    13861 aatcgctgcg ccgtcctgtg cgctaacctt ggcggcgaca cagacaccat cggcgctatg
    13921 gcgacggcga tttgcggcgc gttgcatggc gttaacgcta tcgatcctgc attaaaggcg
    13981 gaactggatg cggtaaatca gcttgatttc aaccgctatg ccacagcgct ggcgaaatat
    14041 cgtcaacaac gggaggcggt atgagcggcg ctcgattaca cacgctgctg cctgaattaa
    14101 cctcgcgtca gccggtgatg gtcgtcggcg cggcggtcat tgatgtgatc gccgacgctt
    14161 atgccctccc ctggcgtggg tgcgatatcg aactgaagca gcagagcgtt aacgttggcg
    14221 gctgcgcact gaatattgcc gtggcgttaa agcgcctcgg catcgaagcg ggtaatgcct
    14281 tgccgctcgg tcagggcgtg tgggcggaga ttattcgcaa ccggatggcg aaagaggggt
    14341 taatcagcct gatcgataac gccgaaggtg ataacggctg gtgtctggcg ctggttgagc
    14401 cggatggcga acgcactttt atgtcattca gcggtgtgga aaatcagtgg aatcgccagt
    14461 ggctggcgcg attaaccgtt gcgcctggca gcctgctcta tttttccggt tatcaactgg
    14521 cctcgccctg cggcgaattg ttagtggaat ggctggaaga gctgcaagac gtgacgccgt
    14581 ttatcgattt tggcccacgt attggcgata tcccggatgc attactgccg cggatcatgg
    14641 cctgtcgacc tttagtgtcg ctcaatcgtc aagaggctga gattgccgcc gaacgttttg
    14701 ctttatccgc agagataaca acacttggcg agcaatggca ggagaaattt gccgcgccgt
    14761 tgatcgttcg tctcgataaa gaaggcgcat ggtatttcag caacgacgct tctggctgca
    14821 ttccggcatt tccaacgcaa gttgtagaca ccattggggc gggcgacagt catgcaggtg
    14881 gcgtacttgc cgggctggcc tctggtctgc cactggcgga tgccgtatta ctgggcaatg
    14941 cagtggcgtc gtgggttgtc gggcatcggg gcggtgattg tgcgccaacg cgcgaggaac
    15001 tactcctcgc acacaaaaac gtatagatcg ctgcgacagt ggctaatgct gtactcaata
    15061 ggccgttgct gttggtcaag cgccacttgc ttgatcacca gcaccggtat tttgctatct
    15121 aactgaatat gtgactgaaa ctcggcatcc ggcatccggg cgctaacgcg ggaacgcgta
    15181 cgttgtaggt aaatgtgctg gctgcggaaa tagtcataaa gtgaaatccc gatggcatca
    15241 acatcatgaa ttaaatgcgc cggaacccac gattcctcaa tcgataccgc ttcttcatcg
    15301 acatagcgaa tacgcttaag caaaaagaca tcacttcctg cttcgaccgc cagctgctgc
    15361 gcgacttctt cgggacattt cacgacacgc ttgttaaccc atagcgtatc gggctttttc
    15421 ccgcgcaata ccacctgctg agaaaaacct cgcgcttctt tcaacgagta ttcgaagatg
    15481 ttgttgatct gcgtgccgta accgcgcgaa cgcgtcacca caccctcttc ttccagcgcc
    15541 tgcatcgcct tgcgcaccgt aatgcgcgaa acgccggtta actgacttaa atcacgctca
    15601 ccgggcaaaa tattgccatg ctccagcacc ccgctgcgca cggcattttt taccgtttcg
    15661 gcaaacttaa tataaagcgg cgtgttatcc gccgctaaaa tacgctcgtt caactgagcg
    15721 ataagctggg tatgcgcttg ttccatttgt ctttttcctg ccggggagtc tggtgggagt
    15781 atatcactgc ttcttattta aggcgtttct ttaatcccat caacgaatcc ctgcaactcc
    15841 tccaccgtgc cattaaacac attaaaatcc accggaccat tgatgccatc tacctgtcca
    15901 cggtcggaat actgccagaa gcgccaggcc attccgtcat tgtccggacg acgttgataa
    15961 tagtgagcca cccaccacgg atattcatta aaatagcccg ccagattggt gtgataaaaa
    16021 acggttcctg agtaaataat cggctttttt cccgtacttt tttcgaccat ttttagccac
    16081 tgacttactc gtttgcgtaa ttcttttgcc gataattttc cccgttcttc tacgtccagt
    16141 acagcaggga aatcgccttg tgagaaatcc accgtttgca gaaataatcg tgcctgaacc
    16201 ggcgctgcta ccgacgggga gaaataatga tacgccccgc gcagcaggcc attttcgcgg
    16261 cttagttgcc agttacgcga aaaatacggg tccaccagct tttcgccttc cgtcgcctta
    16321 ataaaagcaa actgtaagcg gataccgttg tcgcgcattt ttgccacccg ctgccagtcg
    16381 atccgctcct gccagcgaga aacatctatt ccgtgaatgg tgtaactggc aggaatgcga
    16441 atagcgaaag atttaaccgg gcgataaccg tagaaatgga tgtagtctgt aatctgaact
    16501 gctgtcgaat agaaaaaatt caccgtctga cgcggataaa ttgcaacgat ggaaattagc
    16561 ccaagagcgc ataatagaga ggtgagtttt tttcgactgg taattcttag ctgcattggt
    16621 ttcatccctg aatgtcagtg ccaaaggctg acaataacca aagcagctat agtacggtgc
    16681 tcaccaccag gcgtggaagt ggtgaaccgg accaataccg tgaccaactt ccagcgtgtc
    16741 ggcctgggct aatgctgatg aaagccagct ttttgcctcc tgtacggtgt cagcccagtt
    16801 tgtatggcgc gggcgtagtg cagccaacgc cgcagagagc gtacaaccag tgccgtgggt
    16861 gtttttggtc ataatgcgcg gtgcggtaaa ccgttgttca ccctcgcggg taaacagcca
    16921 gtccgggctt tgctcatcat ccagatgacc acctttcatt agcactgcgc cacagcccat
    16981 cgccaacagc gatcgccctt gttccagcat ttcctgttcg gtgcgcgcgt gtggcgcgtc
    17041 gagcaaggcg gcagcttcgg gcaagtttgg cgttattaat gaaacctgtg gcaataatcg
    17101 actgcgcagc gtagcaaccg ccgaaggtga aagcagcggg tcgccgcttt ttgccagcat
    17161 aacggtgtcg agtaccacgt tttggatctg ataacgttgc aaccgttctg ccaccgcttc
    17221 aacaatatcg gtttccgcca acataccgat tttagtggtg tcgattcgca catcgctgaa
    17281 caccgaatcg agctgggcgg cgacaaaatc aggctcaatg cgatacaccg actgtacgcc
    17341 acgggtattt tgcgccacca gtgcagtaat aactgagcaa ccataagcgc caagtgccga
    17401 gaaggtttta agatcggcct gaatccccgc accaccactc ggatcagtac cggcaatcgt
    17461 cagagcgtta attcgtttca tgcctgcacc tcctgcgtca attgccagag cgcatcaagg
    17521 aaatgtggaa caaaactgcc tggcccctcg cttctggcga ctgcgcgttc tccggcttgt
    17581 ttcatccagt gacaggcaga tgcgacattt tccagcgtat cgcctggtaa cgcacagcag
    17641 gcagcgacaa ccgccgataa tgcacagcca gttcctacca ctttggtcat taacggatcg
    17701 ccaccgtgaa tgccaacggc gcgatggcca tcggtaacat aatccacctc gccagtgacc
    17761 acgacgattg cgccagtttc ccgtgccagt gtttgtgcag cgggtatcgc gttagctgcg
    17821 gcgtcagtgg tatccactcc ccgtccacca ttagcaatgc cagctaatgc catgatttcc
    17881 gaagcattac cacgtatcgc tgccggttta aaagataaaa gttcatgaca aaaatggcgg
    17941 cgataatcga gcgcaccaac cgctactgga tcaagcgtcc agggtgtttg agagcttttt
    18001 gcttgctcaa cggcagcacg catcgcctga gcgcgtggct gcgtcagtgt gccaacgtta
    18061 atcaacaagg cactggcgat agccgcaaac tgactggcct cttcggtttc gataaccatc
    18121 gctggcgatg caccgagcgc cagcaaggta ttggcagtaa aggtttgcac cacatcgttg
    18181 gtcatgcagt gcacaagagg ggaatgttgg tgaaaaaggt gtaacgcgtg cgcagattgc
    18241 gctgaactca gcaggtcgac ttgcatagtt tgctcctgcc ataacgtgaa gaagcaatga
    18301 cctggtggtc cgtgacttcc ctacgctggc attatccaga tcaggtgata cgggtatttc
    18361 tcagccttca cgcagaaggg caccccgagt cgtttggttg cgatgataaa tcgcagagga
    18421 ggatggtaat gtccagcgca cgcgttgtaa acgaggaaaa acggcagttt tacaatcgcg
    18481 ttaataaatt atttgatata tgaatccagc accttcagaa cgacatccag atcttcttca
    18541 cgttttagct catccccctg gtgaacgatg tgttccgtca gatgaccttt aatcacttcc
    18601 cgcatcagac cgtttaccgc gccacggata gcagcaatct gttgtaaaac tgcagcgcat
    18661 tcgtgcggct cgtcgagcat tttcttgagc gccacgacct ggccctgaat cttactggca
    18721 cgcgctttca gtttctgttt atcacggatt gtatgagaca tggcaacacc tggttaacaa
    18781 gaatatgaaa aatcatagca ctattaatct actggggggt agtatcaggt actggggggg
    18841 agtagaatca gattgccgaa ttaatactaa gaattattat catgaccgaa tttacaactc
    18901 ttcttcagca aggaaacgcc tggttcttca tccccagcgc catcttactt ggtgcgcttc
    18961 atggcctgga accagggcac tcaaaaacga tgatggcggc gtttatcatc gccatcaaag
    19021 gcaccattaa acaagcggtg atgctcggac tggcagcaac tatttcgcat accgcagtgg
    19081 tctggttaat tgcctttggc gggatggtga tcagcaagcg ctttactgct caatcagcag
    19141 aaccgtggct ccagctgatt tccgcagtga tcattattgg caccgcgttc tggatgttct
    19201 ggcgtacctg gcgcggcgaa cgcaactggc tggagaatat gcacgagtat gatcatgaac
    19261 atcatcacca cgatcacgaa gatcaccacg accatggaca tcatcaccat cacgaacatg
    19321 gcgagtatca ggatgcccat gcacgagccc atgccaatga cattaaacga cgctttgatg
    19381 gtagagaggt caccaactgg caaattttgt tatttggctt aaccggtggt cttatcccct
    19441 gtccggcagc aattaccgtg ctgttgatat gcattcagtt gaaagccctg acactgggcg
    19501 caacactggt cgtcagtttc agcattggcc tggcgttaac gcttatcacc gtaggcgttg
    19561 gcgcagcaat cagcgttcag caggtcgcaa aacgctggag cggatttaac actctcgcta
    19621 aacgcgcccc ctatttttcc agtctgttga ttggcttagt cggtgtgtat atgggcgtac
    19681 atggcttcat gggcataatg cgataactca atcctttagg cttgcatgtt atcttcagcc
    19741 caggatgatt cttaaatcag ctatttccgc tgactctctg ctcgctaagg atgcttttag
    19801 ggcatccttt catttacact ttttacgaaa tcatgggatc actaacaaaa tatcgcttgt
    19861 cagttatatt gtatggcagg aaagatatgc gactgatatt acagatcccc aaagtggaga
    19921 gtttatgacc attaaaaata agatgttgct gggtgcgctt ttgctggtta ccagtgccgc
    19981 ctgggccgca ccagccaccg cgggttcgac caatacctcg ggaatttcta agtatgagtt
    20041 aagcagtttc attgctgact ttaagcattt caaaccaggc gataccgtcc cagagatgta
    20101 ccgcaccgat gagtacaaca ttaagcagtg gcagttacgt aacctgcccg cgcctgatgc
    20161 cgggacgcac tggacctata tgggtggcgc gtacgtgttg atcagcgaca ccgacggtaa
    20221 aatcattaaa gcctacgacg gtgagatttt ttatcatcgc taaaaaaagc cccctcatca
    20281 tgagggggaa atgcagacac cttgttattt tttattatta gccacttgct cgtcttgctt
    20341 gttattagtc gtatttcacg ttgattaatg cggttgcctc cagtgcgcca gatttaactt
    20401 tgtttgtatc gtagacgtag taactggcag ttatcggaat tgaaaccgtt gtatctgtaa
    20461 gttttgactt tgccgcaatt tcttttaaat ttgtgtatcc tttactgctg ttagtgatat
    20521 ttaaaagtgt gactgacgaa ccattacttt caagaataaa tcctacgcca ttatcttccg
    20581 cacctttcag tattgtgttg ctgttggtta acaagtcaga acttgataaa tacacctgca
    20641 ttttccgtga tgtttgattt tgttgaccta ataaattttt acaacgcaga ataatatccc
    20701 cttgtttact atttattgtt gctttgttac ctgtggctgg taattgtgaa acgggaatac
    20761 tgtctaaagt aattaataaa tcgtccggtt tgcaggttgt ggttatcggg ttgtatgaca
    20821 atgtcagatt aaaggaatag acacctgcat tttgtgccaa tgcatttctg tagctattta
    20881 cacatgcatc ccatgacttg ccacctaata aacacagtag aaattgtact gcggcactcc
    20941 cgcgtgtcga tgatgaagca ctggataatg tcgcaactcc attaatcatc actgaaccgc
    21001 cgccccccgc agaaacattc acttttgcat tactggccgc aggtgtcacc gttaccgaat
    21061 aaccactggt gaaactggtc tgattatttg ataacgtgat gttgttttta ttggtccatt
    21121 caaaatgtaa atttaattta atggtatcgt tataaagtcc aacaataata tccgacgggc
    21181 tcataggggt gatagtattt gtactcacgc atgacgaatc attaaaatta tgctcatatg
    21241 tcgccatttg tgtttgagta agtgcaaaat ccccctgaac aaccaaattg tgctgaacag
    21301 ataactcact ataacatgcc gcatagctca caggcataac catcatcatt actataaata
    21361 acattatacg aatattcata accacctgac tattactggc aaatatagtt tctactttca
    21421 tcaatctctt taccgaaggt gattgtgcat gaaagtcctt gttgcttatc aattgctaca
    21481 ttaaccgatg gcggtacttc attggtgcga ataaataact ggcttccctg accgacaacg
    21541 ccaatattat gaccatggat atcattgact tcataaccaa acattaatgg ttgcccatcc
    21601 gctcttaacg cttttataaa ccagggcttg cgctgatcgg tatcaaaatt aaccagtaca
    21661 accgcgccgc gataaggggc ggcaattttc cggttgccac gtaattctgc ttcgctatcg
    21721 ctttgcgaca catccagcat caggtgattt tcccgataag gtgtcattcc gtcgtatacc
    21781 accactccat tacggtttgt tgtgcgatat ttttgcccat tgacataagc atctttaatt
    21841 cctggcgcat tcatcacagc aaacgtttcg gaaagacggt tcgccagatt aacgcccccc
    21901 gaccaggcga caatgccccc tgaaacactg gctccagcct gtcgataagt actcgactga
    21961 ctataactgc cattcactgt cgcaaccggc gcgttccagg tcaaattcgc cccagctgtc
    22021 gtttcatttc cctgattctg ataactcagg ttgaccccat agttaaactg atcccggctt
    22081 ccaacggttc ctgataatcc cgtattattt gaggcaaacc cctgatcatc aaacgtcgtt
    22141 gagttagaca tatatatttg ccgacgaggc gtcgtaacgt catcacccca atcaaaggga
    22201 atcgatataa aaatattaaa acgtttctct tcatgatgat tctcgtcata cgcctggctt
    22261 gccgcgagga tatagcttat ccgccgccag ttattggaat aactcaactg ataatcctta
    22321 ctgctgccgc tacgccccca gtaatctcgc cataacgtac ttaaggacac agacccccag
    22381 ccttctggca atgactggct catattggca gagaagctat ttttacggcc aaaatcgttc
    22441 tggtaataat cggcaatgtc atagacatcg ttttcatcac ggcgataatt atctttattg
    22501 tttgcccaaa cgtgatcatt aaatgtccgg taatcacgcg atgaataacg ccaggccgcc
    22561 agaccaaaac gcgtcgacgt ttggctcaca aatttgttgt aggcaatttg ataactttgc
    22621 ccgtcaaaca catcgccgtt gtcttgttta ctatgcgact tcgtggcatc gacggaaatg
    22681 gcaccaaagc gtgtattcca gccagtcccc aaagtaaacg cgtaataatt attcgcgacc
    22741 atcgagccac catacagcgt caataaatta ttaaaaccat actgataacc cgcctggaca
    22801 aaatcacttt gtttgctcgc cccttcaata tggctacgac ccgccgcaaa atcatatttc
    22861 gatacgccgg gttgcagcat atttggcact gctgcataag gcaccagata ggtggttacc
    22921 gagccgtccg cctctttcac gctgacatca agatctgctc caccaccggc caactgcaaa
    22981 tctgtaatcg cgaacgggcc aggaggaacc tctttctgat aaaccacaaa accgttctgt
    23041 tcaatagtta ccagcgcatt actctgagca atcccctgca cccgtggcgt aaaattttgt
    23101 ttcgagttag gcaacatctg catatcacga aacaaccgca caccgctgaa gcgaacagaa
    23161 tcaaaaatat cgcttgatgt gtacatatca cccacgcgaa gcgtgccgag aagttgggca
    23221 aatccacgtt ccagatacag ggtattgctt ttccacaccc ctggattgtt atttgtttta
    23281 ctgaaactgg catcagaatg cagttgccac cccagtaaat ttaacccgct gttaaaacgt
    23341 acatatgtac tcttactatt acccgacgct ttatagtcac tgtaatactg actcacataa
    23401 taagaggtat aaaacgcatt aataccccgc tcccagtttt ccggcggaac atagccactt
    23461 tccagttctt ccacccaggc ctgcgggaca ctgaaatcga gacgaaaaac cccgatatcc
    23521 caggtatagc tcctaccctg aacaagttgc tcaaatgtta aacattgctt accgctggcg
    23581 aagttatcgc tattaatgcc taaccgcttg ataacttcta ttgataaaca tgtttcttgc
    23641 gggttgtctt taacaataat ctcatatttc ccgcgccatt gcttattgac ataaatatcg
    23701 atgtcatact gccccggtaa gggttgatta tcatcaagac gaatatttgc aacctgctgg
    23761 tctttcattc cacctatcat aaaatgggta tcaaaggttt cttcagctgc ataagcttca
    23821 atgccgagca ataacgctac gattgctgat gcaagtgggg tcattctcaa cataggcagc
    23881 tcctgcaatt aaattttgtc actaatatag ttgccgtggt catcgataat ggtcagatac
    23941 cagttatttg cattattact tttgacatta acactctgac tttctaaggg ggcaatcata
    24001 atagtttcat aattgacttt aacattatta gctttgacat ccgaaatcgt cacccaatta
    24061 gctgagtcat tttttatcac caatccattg ccactgcgat ttaccagtaa ctttttaaag
    24121 gtcgctttat ttaccggagc aatacccgct ggccggtaaa acaacttaat tctgttttgc
    24181 atcgcaaact tcagtgcatt tttgccttct tgctctggac tatttggtgg aatatccaga
    24241 acattcagat aaaaaatgct ttctttatta gtgggcagtt tattcggcat aattttgatt
    24301 tttacttgct gcccggaatt tgcccctatt tttgccactg gtggcgttaa catgaaagga
    24361 acctgaattt tttctggtgg taacgacgta tcgccatcat caatccacgc ctgcagcagc
    24421 gaagaacggt ttccctggtt catcaactgc accataactt ctttattttc tgccgggtaa
    24481 ataatgcgcg tcccgtagat aacaattccg gcatgtgcag gaaggaccat agaaaaaatg
    24541 agtaaagata ataatccttt catcttaatg cctcttaaat taaaaagccg ccatggggat
    24601 agcggccatg tttattacct ggagaaactt acaattttat ttattaatcc tgcgccacac
    24661 gcataaccag agaagataac acatcacctg attgcactga gttatctgtc agtttcaggt
    24721 attttgcttt aaacggaata gcatattgac cttccgctgt tttataactc tcaatgttaa
    24781 aaggtgcaga aacatccagg acatcgctgt tatcacctaa atagagatag taacccacgg
    24841 tatcgttgct actggctatc gccttatcgt taccggttat tttatcgttg gtaatcaacg
    24901 agagttttac accagcaact tctttcgggc agctaatttt taacatgctg ctggttacac
    24961 cgactgcatc atcataggta gaatatttag ctttaccttc aaagacagtg gttggtacag
    25021 tcggcatatt aatacttact gaatcaccac ccgcttcgaa tttacacgga gattctgcaa
    25081 tattcccctt aatagttaat gttccggtat caacgtctgc agcaaatact ccagcgctca
    25141 taaaaaaaga agaaaagaca gcggcagcaa taattgaacg tttcataata tgttccttaa
    25201 taaaatttat ttttggttgt taagagtctg tatctcttgg aaacaaattt ctcacatcaa
    25261 aaaagttgcc gcaatgtaaa cacattgttt tattgattta aaacaaatta accattgcaa
    25321 tataaataca aaaaatgttt aagagtatta actatttatc gcatctatca attaatgtag
    25381 atttatgtaa atggtattgt tgatatcaat aaaaaagccg aaatcattta tataaatgat
    25441 ttcggctttc taaatgcaat taaaatcaga ttgccaaatt aatcgtagcg atttaacacg
    25501 attcgacgtt tgctatcgct acctgcaaca accacttctg tcgttacacc tttgacgggc
    25561 gaagaaaaca gatgacgggt gtcaacatta tacgttaact gaccacaatg ctgttgaggt
    25621 tgaccattaa ccatagccat actgcatgtt gggggactga tcctgccatt aatcgctaat
    25681 gtggcagtct ctgaagagaa tgcgggagaa gccaatccat aggcaagaaa aataattcct
    25741 gacagccaat acttattcat tgaacgttat ccctgtagta aaggttatgc ctggatagaa
    25801 tgagtgcata acaaactata gctgtacatc cactacacag ccacgaagga tgataatgaa
    25861 gcattgcctg tatgatcaat cgactttgta gagtttcgga cgaaggtccg cagaatattc
    25921 gcagtattaa ataagtgttc attaatgcgg caaaaactaa tacaccgcat caatgtaaca
    25981 tctctgcggt gtatgaagaa taaccagaat ggttaatagg cgttagaccg cgcggaagga
    26041 aatctcgcct ggaatgactt caccctgcca gtagagctga gctgcaacgc ggtcagccag
    26101 ctggcggtag atagcggtaa attcgctctc cggacggctg ataaccgttg gcgtgccttt
    26161 atcgagatcc tcacgtaagg agatgtgtaa cggcatctgc cccagcagct gtgtgtggta
    26221 tttttcagcc agtttctcag caccaccggt accgaaaatc ggttcatggt gaccacagtt
    26281 actgcaaata tgcacactca tgttctcgac aataccaagc accggaacct cgactttctc
    26341 gaacatcaca atgccttttt tcgcatcgat caacgcgatg tcctgcgggg tggtgaccac
    26401 gactgcacca gttactggaa tgttttgcgc cagcgtcaat tgaatgtcac cggtgcctgg
    26461 cggcatatca agcaccagat agtcgagacc cggccacaag gtttcctgca acatctgcat
    26521 taacgccttg ctcgccatcg gtccacgcca caccatcgca ttgtcgtcag tgaccagata
    26581 accaattgaa ttggttgcca ggccatgaga cacaatcggt gccatatggg taccgtccgg
    26641 cgaagttgga cgctgatttt ctgcgcccag catggtggga attgatgggc cgtagatatc
    26701 ggcgtccaga atgccgactt tcgccccttc cgccgccagt gccagcgcca ggtttaccgc
    26761 cgtggaggat ttacccacgc cgcctttacc ggaactgacc gcaatgatgt tcttcacacc
    26821 attaataccc ggctgattct tcacgcgttt taaggtggcg atattgtgcg acagtttcca
    26881 gtcgatagct ttcgccccgg tgatacgcag cagttcggcg ctacattgct cttttaactc
    26941 ttcaaacgcg ctatgccaga cgaatggcat aaccagttcc acatgcaacg tgtcgtccat
    27001 ccaggcgaca tggtgcaacg ctttcagcgt ggtgaggtta tgcttcaggg ttgggtgctg
    27061 aaaattggcc agtgtcccgg cgaccattgc gcgcaaggct tctggtgatt tggcctggga
    27121 ttgttcgttc atcccgactc cttttttgta tagataaacc atcagctgat agtttacctg
    27181 aagaatatag agaagtactt acttaacatt ttcccatttg gtactatcta accccttttc
    27241 actattaaga agtaatgcct actatgactc aagtcgcgaa gaaaattctg gtgacgtgcg
    27301 cactgccgta cgctaacggc tcaatccacc tcggccatat gctggagcac atccaggctg
    27361 atgtctgggt ccgttaccag cgaatgcgcg gccacgaggt caacttcatc tgcgccgacg
    27421 atgcccacgg tacaccgatc atgctgaaag ctcagcagct cggtatcacc ccggagcaga
    27481 tgattggcga aatgagtcag gagcatcaga ctgatttcgc aggctttaac atcagctatg
    27541 acaactatca ctcgacgcac agcgaagaga accgccagtt gtcagaactt atctactctc
    27601 gcctgaaaga aaacggtttt attaaaaacc gcaccatctc tcagctgtac gatccggaaa
    27661 aaggcatgtt cctgccggac cgttttgtga aaggcacctg cccgaaatgt aaatccccgg
    27721 atcaatacgg cgataactgc gaagtctgcg gcgcgaccta cagcccgact gaattgatcg
    27781 agccgaaatc ggtggtttct ggcgctacgc cggtaatgcg tgattctgaa cacttcttct
    27841 ttgatctgcc ctctttcagc gaaatgttgc aggcatggac ccgcagcggt gcgttgcagg
    27901 agcaggtggc aaataaaatg caggagtggt ttgaatccgg cctgcaacag tgggatatct
    27961 cccgcgacgc gccatacttt ggttttgaaa ttccgaacgc gccgggcaaa tatttctacg
    28021 tctggctgga cgcaccgatt ggctacatgg gttctttcaa gaatctgtgc gacaagcgcg
    28081 gcgacagcgt aagcttcgat gaatactgga agaaagactc caccgccgag ctgtaccact
    28141 tcatcggtaa agatattgtt tacttccaca gcctgttctg gcctgccatg ctggaaggca
    28201 gcaacttccg caagccgacc aacctgtttg ttcatggcta tgtgacggtg aacggcgcaa
    28261 agatgtccaa gtctcgcggc acctttatta aagccagcac ctggctgaat cattttgacg
    28321 ctgacagcct gcgttactac tacactgcga aactctcttc gcgcattgat gatatcgatc
    28381 tcaacctgga ggatttcgtt cagcgtgtga atgccgatat cgtgaacaaa gtggttaacc
    28441 tggcctctcg taatgcgggc tttatcaaca agcgttttga cggcgtgctg gcaagcgaat
    28501 tggctgaccc gcagttgtac aaaaccttca ctgatgccgc tgaagtgatt ggtgaagcgt
    28561 gggaaagccg cgaatttggt aaagcagtgc gcgaaatcat ggcgctggct gatctggcta
    28621 accgctatgt cgacgagcag gctccgtggg tggtggcaaa acaggaaggc cgcgatgccg
    28681 acctgcaggc aatttgctca atgggcataa acctgttccg cgtgctgatg acttacctga
    28741 agccggtact gccgaaactg accgagcgcg cagaagcatt cctcaataca gaactgacct
    28801 gggatggtat ccagcaaccg ctgctgggcc acaaagtgaa tccgttcaaa gcgctgtata
    28861 accgcatcga tatgaagcag gttgaagcac tggtggaagc gtctaaagaa gaagtgaaag
    28921 cagctgccgc gccagttact ggcccactgg cagatgatcc gattcaggaa accatcacct
    28981 ttgacgactt cgcaaaagtt gacctgcgcg tggcgctgat cgaaaacgca gagtttgttg
    29041 aaggttctga caaactgctg cgcctgacac tggatctcgg cggtgaaaaa cgcaatgtct
    29101 tctccggtat tcgttctgcc tacccggatc cgcaggcact gatcgggcgt cacaccatta
    29161 tggtggccaa cctggcaccg cgtaaaatgc gctttggtat ctccgaaggc atggtaatgg
    29221 ctgctggtcc tggcgggaaa gatatcttcc tgttaagccc ggatgctggt gctaaaccag
    29281 gccatcaggt gaaataatcc ccctttaagg cgctgcatcg acagcgcctt ttctttataa
    29341 attcctaaag ttgttttctt gcgattttgt ctctctctaa cccgcataaa tactggtagc
    29401 atctgcattc aactggataa aattacaggg atgcagaatg agacacttta tctatcagga
    29461 cgaaaaatca cataaattct gggcagttga gcaacaggga aacgagttgc atatcagttg
    29521 gggaaaagtt ggcaccaaag ggcaaagcca gataaaaagt ttttcagatg ctgcggcagt
    29581 ggcaaaagcg gagcttaagc tgattgcgga gaaggtgaag aaggggtatg tggagcaagc
    29641 gaaggataat tctttgcaac cttcccaaac ggtaacgggc tctctcaagg tagcggactt
    29701 atccaccatt attcaggaac aaccctcttt cgtagcagaa acccgtgcgc ctgacaaaaa
    29761 tacagatgct gttttaccgt ggctggcgaa agatattgct gtcgtttttc cgcccgaagt
    29821 tgtacacacc acgttaagtc atcgccgctt tcccggagtt cctgttcagc aagcagacaa
    29881 attgacccaa ttacgtcgct tagcctgtag tgtgtcgcaa cgggataata aaacagccac
    29941 atttgacttc agcgcctgtt ctttagaatg gcaaaacacc gtcgcccagg cgatcagtca
    30001 gatcgacggc ctgaaaacaa cacagctacc atcaccagta atggctgtac tcacggcact
    30061 tgaaatgaaa tgcacaagat ataaagtgcg tgaggatgtt atggatcaga tcgtccagga
    30121 aggcggtctg gaatatgcta ctgatgtaat aatacacctt caacagattg atattaaatg
    30181 ggattatgcg aataatgtca ttattattct gccgtctggc attgcacctg actacttgga
    30241 gcaatattcc agatttgaat tacgcctacg taaacattta tcactggcgg aagagtctct
    30301 ctggcaaaaa tgtgcacaaa aacttattgc cgcaattcca catattccag aatggcggca
    30361 accattaatt gctttgttat tacccgaaaa accagaaatt gcacatgaaa ttgcccagcg
    30421 tctactgggg caaaaaaaat taccctcgct tgagtggtta aaaatagtgg cgactgatga
    30481 gcacattctt gcctcattag aaaaatatca cgagccatat gccatttttg atgattacta
    30541 ttgtggtgcg atatggtcag ccaccgtatt acaggagcaa ggtgttgcag ccctgccccg
    30601 atttgctccc tatgccgcaa gtgactactg cgccgatgtg ttgcgtcata tcaatcatcc
    30661 gttcgcatta acactgctta tacgtgtagc cgggcatact aaacgctgtc acgatcggat
    30721 gacgaaagcc tgcgctgcgt tcccacatgc agcaatggcg gcactgacgg aacttcttgg
    30781 gcaaaaagaa gagaacagtt ggcgcattat gctaatgaca atgcttatct cacaaccagc
    30841 actggcagaa caggtcattc cctggctctc gacacccgca gttgccgtac tgaaatcatg
    30901 ccagcaacaa ctgacacagc cctcaaacca tgccagcgcc gatctactgc cagccgtagt
    30961 agtctcccct ccctggcttt cgaaaaagaa aaaatcgccg attccggtgc tggatttagc
    31021 gccattaggc attgagccaa tctgttatct gacagaagaa atcagtaatc aacttttggc
    31081 gaaatatatc tggtattcaa aacacatcac ggttagccat gaagaaagta ctaccaacct
    31141 gttggcaagg atgggttttc aacgacggat cgctggtaca tatattaaag ctcccgaagc
    31201 ggtagttgag gcatggctaa atgaagatta ttcaacctta ctaagtgaat ttaaggtgtt
    31261 tcattcacct accgggcatt attggcagtt ggggattttg acaacattgc cgctggagaa
    31321 agcagtaaaa gcatggaatg cccttaccct atctccacat accgataccg aatacgccat
    31381 gttacatttt ggactcaaag ggttacctgg gttagtaaac tcacttgcac gctatccaca
    31441 agaagccttg cccatcacga attacttcgc agcgagtgag ctggctcctg ccgtcgcccg
    31501 tgccttcaac aaactgaaaa cgctacgcga aaacgcccgt agctggctgt tgaaataccc
    31561 ggaacatgcc cttaccggcc tgctgcctgc ggcgctcggc aaagccggtg aagcacagga
    31621 taacgcccgc gctgccttgc gtatgcttac cgaaaacggt catcagccat tactgcaaga
    31681 aatcgcccga cgttataacc agccggaagt aaccgatgcg gtgaacgctc tgcttgcgct
    31741 cgatccctta gataatcacc cgacaaaaat ccccactctt ccggcctttt atcagccatc
    31801 gctctggacg cgcccggtat taaaagcaaa tgcccaatca ctgccagata gcgccctcct
    31861 ccacctcggt gaaatgctcc gcttccctca ggaagaggct ctgtatccgg gattattgca
    31921 ggtgaaagac gtctgttccg ccgactcact ggcgggattt gcctgggatc tgtttaccgc
    31981 ctggcagacc gctggcgcgc cgtcgaaaga gagttgggcg ttcactgcgt taggcgttct
    32041 cggtaacgat gacaccgccc gcaaactgac gccattaata cgcgcctggc ctggtgaatc
    32101 ccagcataaa cgcgccaccg ttgggttgga tattctcgct gctatcggta gtgatatcgc
    32161 ccttatgcag cttaacggca tcgcccagaa actgaaattc aaagcattac aggagcgggc
    32221 aaaagaaaaa attgccgaca ttgccgagag ccgcgaactc acggtggcgg agcttgaaga
    32281 tcggttagca ccggatctcg gtctggatga taacggttcg ctgctgctgg attttggccc
    32341 acggcagttc accgtcagct ttgatgaaac cttaaaaccg tttgtgcgtg atgtttccgg
    32401 cagccgcctg aaagacctgc ccaaaccgaa caaaagcgat gatgaaacgc gggcgaacga
    32461 tgcggttaac cgctacaaat tgctgaaaaa agatgcgcgt accatcgccg cccagcaggt
    32521 agcaaggctg gaatccgcca tgtgcctgcg ccgccgctgg tcgctggaaa acttccagct
    32581 cttcctggtt gagcatccgc tggttcgtca cttaacccgc cgtctgattt ggggcgttta
    32641 tagcgccgaa aaccagctac tggcttgctt tcgcgtagca gaagataaca gctacagcac
    32701 cgctgacgat gatcttttca ccctgccgga aggcgatatc tctatcggca ctcctcacgt
    32761 tctggaaata tcaccaacgg atgctgccgc ctttggtcag ctttttgccg actacgaact
    32821 gctaccaccg ttccgccagc tcgaccgtaa cagctacgcc ctgacagaag ccgagcgcaa
    32881 tgccagtgaa ctgacccgct gggcaggcag aaaatgcccg agcggtcggg tcatgggact
    32941 ggcgaataaa ggttgggtgc gtggtgaacc gcaggatggt ggctggatcg gctggatgat
    33001 caaacctctg ggccgctggt cgttaatcat ggaaatcgat gaaggctttg cagttggtat
    33061 gtcgccagcc gaacttagcg ccgagcaact cttaagcaag ctgtggctat gggaaggcaa
    33121 agcagaaagc tatggctggg ggagtaattc aacacaggaa gcgcagttct ccgtactcga
    33181 tgccatcacc gccagcgagc tgattaacga tattgaagcc ctgtttgaat aaggaaagag
    33241 catggacaag gaattaccgt ggctggcgga taacgcccaa ctggaactga aatataaaaa
    33301 aggcaaaaca ccactcagcc atcgcaattg gccgggcgaa ccagtgcctg ttatcactga
    33361 aagcatcatt cagacactgg gtgatgaatt gctacaaaaa gctgagaaga aaaaaaacat
    33421 tgtctggcgt tatgagaatt tttcactgga gtggcagtcc gccattacgc aggccatcaa
    33481 cttgatcggc gaacacaaac cctcaatccc ggcccagaca atggcggcgc tagtctgtat
    33541 cgcgcaaaat gacagccaac agttgctcga cgaaatcgtc caacaagagg ggctggaata
    33601 tgcgactgag gtggtgattg cacgccagtt tattacacga tgttatgaga gtgatcctct
    33661 ggtagtcaca ttgcagtatc agaacgagga ctatggctat ggttatcgct cagaaaccta
    33721 taacgaattc gatctccgac tgcgtaagca tctctctctg gcagaggaaa gctgctggca
    33781 gcgttgcgcc gacaaactca ttgccacact gccaggaata accaaagttc gccgcccttt
    33841 tattgcgctg atcctccccg aaaaaccaga aatcgccaat gagttggtaa gccttgaatg
    33901 cccgcggact cattttcatt ctaaggagtg gttaaaagtt gttgctaatg accccacagc
    33961 ggtgagaaaa ctcgaacgct actggagcca ggatatattt agcgatcgag aagccagcta
    34021 catgtcgcat gaaaaccact tcggctacgc ggcctgcgcc gcccttttgc gcgaacaagg
    34081 actggcagcc gttccgcgcc tcgcgatata tgcccataaa gaagattgcg gcagtctgct
    34141 ggtacaaatt aaccatccgc aagtcatccg caccttgctg ttagttgctg ataaaaacaa
    34201 acccagcctg caacgtgtgg ctaaatacag taaaaacttc ccccatgcga cactcgccgc
    34261 actggcagaa ctgctggcgt taaaagaacc accagcccgc ctaggttatc caatcatcga
    34321 agacaaaaag ctgcctgcac agcaaaaagc acgcgatgaa tactggcgta cgctgttaca
    34381 aacgctgata gcatcgcagc cacaactagc agaaagggtg atgccgtggt taagtactca
    34441 agccagggca gtgctgaata gttatttatc ggcaccgcca aaaccggtta ttgatagcac
    34501 cgataacagc agtctgcctg aaatgctcgt ttcaccaccg tggcgtagta agaaaaaaat
    34561 gacagctcca cgtcttgatt tggcaccgct cgaattaact ccgcaaattt actggcaacc
    34621 aggcgaacaa gagaggcttg ccgccactga gtctgcccgt tatttcagca cggaatctct
    34681 tgcggaacgc atggaacaaa aaagtggacg agttgtatta caggaactgg gttttgggga
    34741 tgatgtatgg ctgtttctga attatatact ccccggaaaa ctggatgctg cacgcaattc
    34801 actcattgtt cagtggcatt actaccaggg gcgggttgaa gagatcctga atggctggaa
    34861 ctccccgcaa gcacaattag cagaacaggc gctccgcagc ggtcacatag aagcgttaat
    34921 taacatatgg gaaaatgaca acttctcacg ttatcgtccg gaaaagagtg tctggaacct
    34981 gtatttattg gcacagttgc cgcgtgagat ggctttgacc ttctggctgc gtatcattga
    35041 gaaaaagcat ctgttcgcgg gtgaggacta ttttctcagt atcctcggat tggatgcgct
    35101 accaggtctg ctgttggctt tttcacatcg tccaaaagaa acatttccgt taattttaaa
    35161 ttttggcgca acagaactgg cgctgcctgt tgcccgcgtc tggcgacgtt tcgcggcgca
    35221 gcgtgatctg gctcgccagt ggattttaca atggccggaa catacggcta gtgcacttat
    35281 ccctcttgtc tttaccaaac ccagcgataa tagcgaagcc gcattacttg ccctgcgttt
    35341 actgtacgaa cagggacatg gcgaattgct acaaaccgtg gcaaaccgct ggcagcgtac
    35401 agatgtatgg tctgccctgg agcagttgct taaacagggt ccaatggaca tttacccggc
    35461 acgcattcca aaagcccctg atttctggca tccggcaatg tggtccaggc ctcgacttat
    35521 cactaataat cagcctgtta ccggtgacgc tctggaaatt atcggcgaaa tgctgcgctt
    35581 tacccagggg ggacgttttt atagcgggct ggaacaactg aaaacgttct gccagccaca
    35641 aacgctggca gcttttgcct gggatctctt cactgcgtgg caacaagctg gtgcccccgc
    35701 aaaagacaac tgggcatttc tggcgttaag tctctttggt gacgaaagca cggcacggga
    35761 tctgacgaca cagatcctcg cctggccaca agaaggcaaa tctgcccgtg ctgtcagcgg
    35821 cctgaacatc cttaccctga tgaataatga tatggcgctg atacagctgc atcatatatc
    35881 gcaacgggct aaatcccgcc ccttacgtga taacgcggcg gaatttcttc aggtggtcgc
    35941 agaaaatcgc gggctaagcc aggaagagct agcggacaga ttagtcccaa ccctgggcct
    36001 tgatgatccg caggcgttga gttttgattt tggtccccgg cagtttaccg ttcgcttcga
    36061 tgaaaacctc aacccggtta tctttgatca gcaaaacgtt cgccagaaaa gcgttccccg
    36121 gttgcgcgcc gatgacgatc aactgaaagc gcccgaggca ctggcccgac taaaagggct
    36181 aaaaaaagat gctactcagg tgagcaaaaa cctgctcccg cgtcttgaag ctgccctacg
    36241 taccacccga cgctggtcgc tggcagattt tcatactctg tttgttaatc atccctttac
    36301 ccgcctggtt acccagcgat taatatgggg cgtgtatccg gcaaatgaac cgcgtcgttt
    36361 actcaacgcc tttcgtgtgg ccgcagaggg ggagttctgc aatgcgcagg atgagccaat
    36421 tgacctgcct gcggatgctc tgattggcat tgcccacccg ttagaaatga cagcagaaat
    36481 gcgcagtgaa tttgcccagc tttttgccga ttacgaaatt ataccgccac ttcgccagtt
    36541 gacacggcgc acggtgctgc tcacgcctga cgagtcagcc agtaatagtt tgaatcgctg
    36601 ggaaggtaaa tctgctaccg ttgggcaact tatgggaatg cgatacaaag gctgggagtc
    36661 aggctatgag gacgcatttg tctatgacct gggtgagtac cggctggtcc ttaagttttc
    36721 acccggtttt aaccactaca atgttgatag caaagcgcta atgagcttcc gttctcttcg
    36781 agtgtacagt gacaataaat ccgtcacttt tgccgaactt gatgtgtttg atttgagtga
    36841 ggcgttaagc gcacctgacg tcattttcca ttaaaacaca gcgggcagtg atgcaactgc
    36901 ccgttatcaa cacgacttac cagcggggaa agcgatgatc gtgcaaaaag agctggttgc
    36961 tatttacgat tatgaggtcc ctgtacctga agatccgttt tccttcagac ttgagatcca
    37021 taaatgctct gaattattta caggttccgt ctatcgactg gagcgattcc ggctacgtcc
    37081 aacatttcat caacgtgatc gagaagatgc tgacccgcta ataaatgatg cgttgattta
    37141 tataagagat gagtgtattg atgagcggaa attacgaggt gaatcacctg aaactgtaat
    37201 agcaattttt aatcgtgaac tacagaatat attcaaccaa ctaatagaat attagtttat
    37261 taaaggggga agcggttttc ccccttagtt gcgtttcaat ttgcccatta cttcaacaaa
    37321 tcaatcaacc gtaacagaga cactaatagc tccagtacgg caatgagcac ggttaacttt
    37381 tgtgtcagcg tgtccatccg ctctccttat taaggagcgc aacaccagca ccttaccctt
    37441 acactgcctg tcgatactgg tttacgtttg ttgagtcgcc atgttgcact ccggatcaga
    37501 gcactacctg cggcaccacc cgtccggtag ccaggacttg aaatgggttc gatccggcgc
    37561 aacttcccaa cagtcaggat tataaatctc attatcttaa ttgcaacact gtccagaggt
    37621 ggttataatt cgttcgttga gatgccatgt tgcactatca gtaacttaac atcaaagtag
    37681 taaataaaag aacctgcctc accagcaggt ttttttattt tctgcgatct actttccaga
    37741 tattttttgc caatagccca ccataaatat tcacatcccg gtcaaatggt gcgttgaata
    37801 taaaatcgat gaatttataa ataaaaatga gttatatgat gaattaataa aaacagtaat
    37861 cattttatta aagggggaag cggttttccc ccttagatgc gtttcaattt gcccgttact
    37921 tcaacaaatc aatcaaccgt aacaaagcca ctaatagctc cagtacagca atgagcacgg
    37981 ttaacttttg tgtcagcgtg tccatccgct ctccttatta aggagcgcaa caccagcacc
    38041 ttacccttac actgcctgtc gatactggtt tacgtatgtt ggaccacgat gttgcactcc
    38101 ggatcagggc accacctgca gcaccacccg tccggtagcc aggacttgaa atagattcga
    38161 tccggcgcaa cgtcccaacg gtctggatta taaatctcat tatcttaatt gcaacggggt
    38221 ccagccgtgg ttataattcg ttcgttggaa cacgatgttg cacaggctgt ggtgttaggc
    38281 ctgaaagtag taaataaaag aacctgcctc accagcaggt ttttttattt actgtgatct
    38341 gctttccaga tatttttcgc tcaaacaact aatgcgccaa acatttattg cgcgtaaaat
    38401 atcgtttatt tcattaatac atttcaggga tgaatatatg tcaccgcaga ataatcatct
    38461 gcagcgtccg cctgctgctg tgttatacgc cgatgaactg gcaaaattaa aacaaaatga
    38521 taacgcacct tgcccgcccg gttggcagtt aagtttgcct gcggcccgtg cttttatcct
    38581 tggcgatagc gcgcaaaata ttagccgtaa agtggtgatt agtccctccg ctgtcgaacg
    38641 catgttagtc actcttgcca ccgggcgcgg tttgatgttg gtgggggaac ctggcaccgc
    38701 aaaatctctc ctgtctgaat tactggcaac cgctattagc ggcgatgccg ggttaaccat
    38761 ccagggcggc gcatctacta ccgaagatca aatcaagtac ggctggaact acaccctgct
    38821 tatcaaccat ggtccgtcaa cggaagcact ggtccctgcc ccgctttacc agggaatgcg
    38881 cgacggcaaa atcgtccgtt ttgaagagat aacgcgtaca ccgctggaag tacaagactg
    38941 tctgttaggt atgctttctg acagggtgat gacggtgccg gaactcaccg gtgaagccag
    39001 tcagctctat gcgcgggaag gctttaatat tattgccact gccaataccc gcgatcgcgg
    39061 cgtcaatgag atgagtgccg cgctaaagcg tcgcttcgat tttgaaaccg tctttccgat
    39121 tatggatttc gcccaggagc tggaactggt cgccagtgct tcggcgcgtt tgctggccca
    39181 tagcggtatt ccgcataaag tgcctgacgc agtactggag ttactggtac gcaccttccg
    39241 cgatctgcgt gccaacggcg aaaagaaaac gtcaatggat acactgacag cgattatgtc
    39301 caccgctgaa gccgtgaacg tggcccacgc cgtaggcgtc cgcgcctggt ttttagcgaa
    39361 tcgcgcgggg gagcctgccg acctggtgga ctgtattgcc ggaaccatcg tcaaagataa
    39421 cgaagaagat cgcgctcgtc tgcgccgtta cttcgaacag cgtgtcgcca cacataaaga
    39481 agctcactgg caggcttatt atcaagcccg ccaccgcctg ccgtgaggaa agaggcatga
    39541 gcgagccgtt aattgtcggc atccggcatc atagtccggc ctgcgcccgg ctggtgaaat
    39601 cgttaatcga aagccagcgg ccacgatacg tgttgattga aggcccggct gattttaatg
    39661 accgggtaga cgaacttttt tttcccacca gcttccggta gctatttaca gttattgcca
    39721 gtatcaggac ggtgcagccc ccgggcgtgg tgcctggacg ccatttgctg aattttcgcc
    39781 ggagtggcag gcgctacaag ccgcacgtcg tattcaggcg caaacttact tcatcgattt
    39841 gccttgctgg gcgcagagtg aagaagagga cgattcgcct gatacgcaag atgaaagcca
    39901 gcaaactgca ttaccctctg cgctggcgca ctattttgcc caactgcggg gcgatttccc
    39961 cggcgatgca ctcaatcgtc agcgcgaagc ctttatggct cgctggattg catgggcggt
    40021 gcagcaaaat aatggcgacg tgttagtcgt ctgcggtggc tggcacgctc cggcactggc
    40081 aaaaatgtgg cgcgaatgcc cgcaggacat taacacgccg gaattgccct cgctggcaga
    40141 tgccattaca ggttgttatc tcacgcccta cagtgaaaag cgccttgatg tgctggcagg
    40201 atacctttcc ggtatgcctg ccccggtctg gcaaaactgg tgctggcagt ggggcttaca
    40261 gcaggccggt gaacaactgc taaaaactat ccttacccgt ttgcgccagc acaagttgcc
    40321 tgcttcgacc gcggatatgg ctgccgctca tctgcatgcg atggcgctgg cacagttgcg
    40381 cggtcataca ctaccgttac gcactgactg gctggatgcc atagcaggat cgctgattaa
    40441 agaagccctg aatgcgccgt tgccgtggag ctatcgcggc gttattcatc ccgacaccga
    40501 tccgattctg ctaacgttga tagacacatt agcgggtgac ggattcggta aacttgcccc
    40561 ttctacgcca caacctcctc tgccaaaaga tgtcacctgc gaactggaac gtaccgcaat
    40621 ctcccttccg gcggagctta ccttaaatcg ctttaacccc aatggactag cgcaaagtca
    40681 ggtgttacat cggctggcaa tactggagat cccagggatt gtgcgccagc agggaagcac
    40741 actgacactt gcaggcaacg gtgaagaaca ctggaaatta acccgcccgc ttagccagca
    40801 tgcggcattg attgaggccg cctgctttgg tgccacactc caggaagccg cacgccataa
    40861 attagaagcc gatatgctgg acgcgggtgg aatcggcagt atcaccacat gtcttagcca
    40921 ggcggcgtta gcgggtctgg cgtccttcag tcaacaatta ctggagcaac tcacattatt
    40981 aatcgcccag gaaaatcaat ttgccgaaat gggccaggcg ctggaagtgc tatatgcctt
    41041 atggcggctg gatgaaatta gcggtatgca aggcgcgcag atattacaaa cgacgttatg
    41101 cgcggctatc gatcgcacgc tgtggctgtg tgaatctaac ggcagaccgg atgaaaagga
    41161 gtttcacgct cacctgcata gctggcaagc gctttgccat attctgcgcg atctacatag
    41221 cggcgttaat ttatccggcg tttcgctttc tgcggcggta gccttactgg agcgacgcag
    41281 tcaggcaatt catgccccgg cgctggatcg cggcgcggct catggcgcac tgatgcgtct
    41341 ggaacatcct aacgccagtg ccgaagcggc gctgacgatg ctggcgcagt tatccccggc
    41401 acaatccggc gaagcgctgc acggtttgct ggcgctggcc cgccatcaac tggcctgtca
    41461 gccgacattt atcgccggtt tcagcagtca tttaaatcaa ctaagtgatg ccgattttat
    41521 caatgccctg cccgatttac gcgcggcgat ggcctggcta ccaccacgag aacgcgggac
    41581 gctggcgcat caggtgcttg agcattatca actggcgcaa cttcccgttt cggcgctgca
    41641 aatgccgttg cattgtccac cacaggccat tgcacatcat caacaactcg aacagcaggc
    41701 actggcatcg ctgcaaaact ggggagtttt ccatgtctga actgaacgat cttctgacca
    41761 cccgtgagct acaacgctgg cgattaattc ttggcgaagc ggcagaaacg acgctttgtg
    41821 ggctggatga caacgcccgg cagatagacc acgcgctgga gtggctgtat gggcgcgatc
    41881 ctgaacggct ccagcgtggt gaacgctctg gtggattagg tggctcaaat ctcaccaccc
    41941 ctgagtggat caacagtatt cacactctgt ttccgcaaca ggtgattgag cgactggaaa
    42001 gcgatgccgt actgcgctac ggcattgaag atgtggtgac gaatctcgac gtgctggaac
    42061 gtatgcagcc ttcggaaagc ctgctacgcg ccgttttgca caccaaacat ctgatgaatc
    42121 ccgaagtact ggctgccgcc cgccagatag tgcgccaggt tgttgaagaa attatggcgc
    42181 gactggcaaa ggaagttcgt caggcttttt ctggtgtccg cgatcgccgt cgccgctcat
    42241 taattccact ggcgcgaaac tttgatttca aaagtactct gcgcgccaac ctgcaacact
    42301 ggcacccgca acacggcaag ttgtatatcg aatccccccg ctttaacagc cgcattaaac
    42361 gccaaagcga acaatggcaa ctggtcttac tggttgatca aagcggatcg atggtggact
    42421 cggtgatcca ctctgcggtg atggcggcct gtttgtggca gttacccggc attcgtaccc
    42481 atctggtggc gtttgacaca agcgtggttg atctcacggc agacgttgcc gatccggtag
    42541 agttattaat gaaagtacag ttgggcggcg ggaccaatat cgccagtgcc gtggagtatg
    42601 gtcggcaact tattgaacaa ccagcaaaaa gcgtcattat cctcgtgagc gatttttacg
    42661 aagggggttc atcatcattg ctgacgcatc aggtaaaaaa gtgtgtccag agcggcatca
    42721 aagtgctggg actggcagcg ctcgatagca ccgcaacgcc ttgctatgac cgcgatacgg
    42781 cccaggcgct ggttaatgtc ggcgcacaaa tagccgccat gacgccgggc gagctggcat
    42841 catggcttgc ggagaatctt cagtcatgaa ttcactacgt ccggaattat tagaactgac
    42901 accgcaggca ctgacggcgt taagcaatgc cggttttgtt aagcgcagtc ttaaggaact
    42961 ggaaaatggc aacgtcccgg aaatcagcca tgagaacggc gctttaatcg ccaccttcag
    43021 tgacggtgtc cgtacccagc tggcgaacag ccaggcactg aaagaggctc agtgcagctg
    43081 cggggccagc ggcatgtgcc gtcatcgcgt gatgctggtg ttaagttatc aacgactttg
    43141 tgccaccgtc cagcccacgg aaaaagaaga agagtgggat ccggcaatct ggctggaaga
    43201 actggctacc ctgcccgatg ccacccgcaa acgcgcgcag gcgctggtcg ctaaaggcat
    43261 caccattgag ttgttctgtg cgccgggcga aattccctct gcccgcttac cgatgagcga
    43321 tgtgcgtttt tattcccgta gcagtattcg tttcgcccgt tgtgattgta ttgaaggcac
    43381 actttgcgaa catgtcgtac tggctgtgca ggccttcgtc gaggccaaag cgcagcaagc
    43441 agaatttaac catttaatct ggcagatgcg cagcgaacac gtcacatcat ctgacgatcc
    43501 gtttgccagc gaagaaggcc aaacgtgtcg tcaatatgtt cagcaattaa gccaggcatt
    43561 atggcttggc ggcatcagcc agccgcttat tcactacgag gcagcattca accgcacatt
    43621 gcaggcggca gaggcctgca actggcgctg ggtgagtgaa tcactacgac agctacgggc
    43681 aagcgttgat gccttccaca ctcgcgccag ccactatcat gccggagaat gcttacgtca
    43741 gcttgcggca ttaaacagtc gattaaattg cgcacaagag atggcccggc gcgacagtgt
    43801 tggtgaagtt cctcctgtgc cgtggcgcac ggtcgttggc tctggcattg ccggagaagc
    43861 aaagcttgat catctgcggc tggtgtcttt aggtatgcgt tgctggcagg atattgagca
    43921 ttatggttta cgcatctggt ttaccgatcc cgacaccggc agtattttgc acctttcgcg
    43981 cagttggccg cgaagtgaac aggaaaactc accggcagct acgcgtcggc tgtttagttt
    44041 tcaggctggc gcactggcgg gtgggcaaat tgtttcacaa gcagcaaaac gcagtgccga
    44101 tggcgagctg ctgttagcta cccgcaaccg cttaagcagc gttgtgccgc tgtcgcctga
    44161 tgcctggcaa atgttgagcg cgccgttacg ccagccgggc attgtggctt tgcgggaata
    44221 tttacgccag cgtccccccg cctgcatacg gcctcttaat caggtcgata acttatttat
    44281 tctgccggtc gctgagtgta tttcgctcgg ttgggatagc agccgccaga cgctggatgc
    44341 gcaggtaatc agcggcgaag gtgaagataa tctcctgacg ttatcccttc cggcatctgc
    44401 ctgttctcct tttgccgttg aacgcatggc ggcgcttttg caacaaacag acgaccccgt
    44461 gagtctggtt tctggctttg tcagttttgt tgatgggcaa ttgacactgg aaccacgggt
    44521 gatgatgaca aaaacccgcg cctgggcgct ggacgcagaa actgcgcctg tggcaccgct
    44581 accttctgcc agcgttttgc ctgtgccgtc taccgctcat cagttgctga tgcgctgcca
    44641 ggcgttactt attcaactgc tccataacgg ctggcgctat caggaacaga gcgctattag
    44701 tcaggcagag ttgctggcga atgacctctc cgcggtcggt ttttatcggc tggcacatgt
    44761 gttgggacaa tttcgtaata cagaaagcga ggcacgggta gaagcaatga ataacggtgt
    44821 tttactttgc gaacaattat tccccatgct tcagcaacaa ggatgaaata gtgcttttta
    44881 ctaagagttc tactccagtt ccggactgct cacgtcacgg tattaggcat attctatata
    44941 gcccctggtg agagtcacca gtttcttgat taaataaaat ggagttttac atgaaggctt
    45001 tcaataagct gttttccctc gttgttgcat ctgttctggt tttctctctt gctggctgcg
    45061 gtgacaaaga agaatcgaag aaattcagcg ccaatctgaa cggcactgaa attgccatta
    45121 cctatgtcta caaaggtgac aaggtgctta agcaatcttc tgaaaccaaa attcaatttg
    45181 cttctattgg tgcaaccacc aaagaagacg ctgccaagac acttgagccg ttaagcgcca
    45241 aatacaaaaa catcgcgggt gttgaagaat aattaaccta tacagatacc tacgcgcagg
    45301 aaaacgtgac tatcgatatg gaaaaagtgg attttaaagc cctgcagggt atttcaggaa
    45361 tcaacgtttc tgctgaagat gccaaaaaag gtatcactat ggcgcaaatg gaactggtga
    45421 tgaaagccgc tggttttaaa gaagtgaaat aatctgtcgg cggccatgtt tcgcatggcc
    45481 gccatacccg tcttagcttt tcttcacatg ctggcgcgct gccagtccac gcagaaaata
    45541 acgtaaaaat tgatcgccgc attcgcggaa gtttttatga tccggtgcgc gcatcatcgc
    45601 tgtaatttcc ggcatcgaaa cgcggaactg ctgttcggtg aggatagcca gaatgtcatc
    45661 ggttttcagc gaaaacgcga tgcgtaattt tttcagcacg atgttgttat taatgcgacg
    45721 ttccggctcc agtgccggag cagactcatc cttgccgcgt ttttcataaa tcaggccatt
    45781 gaggaatgac gacaaaacaa tgtccggaca acgctgaaaa ccctcttcgt cttctttacg
    45841 tagccagacg gcgatctgtt ccgcggtggc ttcgacatta cccagcgcca gaatacgcac
    45901 caggtcatta ttattggctt tcaaaatgta gcgcacgctg cgcagaatat cgttacttag
    45961 catgaggcct tcaggtgttg atgaggcaaa aagccatttt agcagtcttt tacaggccaa
    46021 tcgcctcttt taagcttttc agataacggc ggctgaccgg cacggttaag ccattacgca
    46081 aaatcaactc ggcctggccg ttatcttcca gacgaatctc ctgtaaatgc gcgaggttaa
    46141 ccagatactg acgatggcag cgcagtagtg gtgtacgact ttccagggta cgtaatgtca
    46201 attcggtaaa gccctctttc ccttcgtggc tggtaacgta gacaccgctc atccgactgc
    46261 tgacaaatgc cacatctttc atttgcagca aataaatccg actatgcccc gtacaaggga
    46321 taaatttcag cgcctgttga ttttccggta acagcgaaac atcctgcttg ctgcgctcct
    46381 gacgcaatcg cgccagcgtt ttctccagtc gcgcttcatc aattggcttc agcagataat
    46441 caaaggcatg ttcttcaaag gctttaatag cgtattcgtc aaacgcagtg agaaaaacaa
    46501 tatacgggcg atgttccggg tcaagcatcc caaccatttc cagaccactg atgcgcggca
    46561 tctggatatc gagaaacagc acatccgggc gcagtttatg caccgcgccg atcccttcca
    46621 cggcgtttga acactctcca acgatttcaa tatcgctctg ctcctgcaaa aatacacgca
    46681 ggttctcccg tgctaacggt tcatcatcga caattaagac tttaatcatg cctcgtccct
    46741 ccatggtagt cgtaacgtta ttcgggtgta actatcaggc tcacaggcga cgcttattcc
    46801 atagtcatcg ccaaaccgtt cacgtaaacg cttatccacc agattcatcc ccagcccact
    46861 ggcattggtt accggttgat acaaaccggc attgtcttcg atctccagca tcaaatgttg
    46921 cccctcacgt cgggcgctga ttgccactcg ccctgtatcc agcagttgtg atgtcccatg
    46981 tttaatggcg ttttccacta tcggttgcag ggtaaacgcg ggcaattgct gctgggataa
    47041 ttcttgcgga atagcaatgt tgacctgcaa ccgcgactgg aagcgcgcct tttcaatttg
    47101 cagataagcg ttcacatgtt caatttcgtc ggcgagagta acaaactccg aaggccgctt
    47161 taagtttttg cggaaaaaag tggaaagata ctgcaccagc tggctggcct gttcgctgtc
    47221 gcggcggatc accgctttaa tggtgttaag cgcattaaac aaaaaatgag gattcacctg
    47281 ggcgtgaagc agtttgattt ctgactgggt gagcatcgct ttttgccgct catattgccc
    47341 ggcaagaatc tgcgccgaaa gcagttgcgc aatcccctcg cccagcgtgc ggtttattga
    47401 actgaataaa cggtttttgg cttcatacaa tttgatggtg cccatcacgc gctgattttc
    47461 gccacgcaac ggaattacca gcgtcgaccc cagtttgcat tgcggatgca aagagcaacg
    47521 ataaggtact tcgttgccat cagcgtagac cacttcaccg gtttcaatcg cttttaaggt
    47581 gtaagtcgaa gaaatcggtt tgccgggtaa atggtggtcg tcaccaattc cggtaaaggc
    47641 cagcaatttc tctcgatcgg taatcgcgac tgcaccaata tccagctcct gatacagcac
    47701 ctgagccact ttcatgctgt tcacttcgtt aaacccctgt cgcaaaatgc cttccgtcga
    47761 ggctgccact ttcagcgcag tggcagaaaa agcagaagtg tatttttcaa acatcgcgcg
    47821 tttatcgagc aatatacgca taaacagcgc cgcgccgacg gtattggtga ccatcattgg
    47881 tgcagcaata ttactcacca gacgcaccgc atcttcataa ggtcgggcga tcgcaaggat
    47941 gatcagcatt tgcaccattt cagcgacgaa cgtgacggca ccggcggtaa tggggttaaa
    48001 gactttatca gtgcgcccgc gacggatcag gatgctgtgt accaggccgc cgagcaatcc
    48061 ttcaacgatg gttgagatca tgcaacttag cgcggtcatg ccccccatcg aatatcgatg
    48121 taagccgccg gtcagaccaa ccagcccacc gacgaccgga ccgccgagta agccgcccat
    48181 taccgcgcct atcgcacggg tattggcaat agaatcgtca atgtgcaacc caaaccaggt
    48241 gcccatgatg cagaagatgg aaaagacgat gtagcagaga aatttatgcg gcagacgaac
    48301 cgtgacctgc attaacggta tgaataatgg cgttttactc attaaccacg caatgactaa
    48361 aaaaacgcac atctgctgaa gcagcagcaa caccagatta aaatcgtaca tacccgcaaa
    48421 ccacacttcc ctttaaaacg cgtaacatac attgcctgcg tttaactttc tttgaactct
    48481 tgcagaaaaa tgagaattcg tgagtacgat cactcaaaat cgcctggcaa aaataaaatc
    48541 accctataga tgcacaaaaa acgggcaaaa ctacctggtt cgcaaaactg cgtctaaagt
    48601 taaaccggga cctcgcgagc aagggtgaga cgatggcgct ttacacaatt ggtgaagtgg
    48661 cgttgctttg tgatattaac cctgtcacgt tacgcgcgtg gcagaggcgt tacgggttgc
    48721 tgaaaccgca acggacagac ggcggtcatc gactgttcaa cgatgccgat attgaccgta
    48781 tccgcgagat caaacgctgg atcgacaacg gcgtgcaggt cagcaaagtt aaaatgctgc
    48841 tcagtaatga aaatgttgat gtgcagaacg gctggcgcga tcagcaagaa acattactga
    48901 cctacctgca aagcggcaat ctgcatagcc tgcgaacgtg gatcaaagag cgcggtcagg
    48961 attaccccgc ccagacactc accacacatc tgtttattcc tctgcgccga cgacttcaat
    49021 gccaacaacc gactctccag gcgctgctgg cgatcctcga cggcgtactg atcaactaca
    49081 tcgccatttg tctggcttcg gcacgtaaaa aacagggtaa agatgcgctg gtggttggct
    49141 ggaatattca ggataccacc cgtctgtggc tggagggctg gattgccagt caacaaggat
    49201 ggcgcattga tgtcctcgcc cactcgctca atcaactacg ccctgaacta ttcgaaggcc
    49261 gtacattgct ggtgtggtgc ggtgaaaatc gaacctccgc ccaacagcag caactcacca
    49321 gttggcaaga acaaggccat gatattttac cactcggcat ttaatgattc gttaacaaat
    49381 gcgctttact gtacaatcct ttcgttaaca taaggagtgc attatgcgca tagctaaaat
    49441 tggggtcatc gccctgttcc tgtttatggc gttcggcgga attggtggcg tcatgctcgc
    49501 aggttatacc tttattttgc gtgctggcta agcgcctgca ccagcctttc aaacaggcgg
    49561 tctgcgatga tcgccgccag tgccaccagt aacgccccct ggatcacata cgcggtatta
    49621 aatccgctaa gcccgatgat gatgggcgta cccagcgtgc tggcccctac cgttgaggcg
    49681 atcgtcgccg taccaatgtt gataatcacc gaagttcgca cgcccgccag aatcaccgga
    49741 gccgccagcg gtagctcgac cttacgcagt cgctgaccac gactcattcc catacctttc
    49801 gcaacttctg tcacgctggc atcgatcgct cccagcccgg caagtgtcgc ctgcaggacg
    49861 ggcagcacac cgtaaaggat caaggcgata atcgctggtt gcagaccaaa gccgatcacc
    49921 ggaacggcaa tcgccagcac tgcgacaggc ggaaaagtct gtccaacggc ggcaatagtt
    49981 tccaccagtg ggcgaaattc cgcgccccac gggcgagtga cagcaattcc ggcaccagtg
    50041 ccaatgatca ccgcaaacaa actcgaaatt cccaccagcc agaaatgagc cagtgccaga
    50101 gctgcaaaac tttcttgctg ataaacgggt cgtggcagtt gtgggaacaa ggcagcaaac
    50161 agcggctggc tgtaaggcag ccagaaaatc agtgccacaa acaaagcaat gagccagaac
    50221 agcggatcgc gcaacatctt catacgctta cgcctccacc agcagatcct gaaaatgcag
    50281 cgtaccgcaa ggctggccct gcgtgttcac caccggcagc acctcgcaac cccgcgcgac
    50341 aaacagggag agcgcatcgc gtagcgtcat ctcttctacc agtgcctcac cttctgcccg
    50401 ttcttcgcga cgcacgtaat ccgccacact acgtaacgaa agcagacgca cacccagttc
    50461 gctacgtcca aaaaactggc ggacaaaatc attcgccgga cgagtcagca tcgtcagcgg
    50521 attgccctgc tgcaccactt caccgtgatc catcaatacc agatgttcag ccagccgtag
    50581 cgcctcatca atatcatgag tgaccagcac aatagtgcgc cccagcaaac ggtgaatgcg
    50641 cgtcatctct tgttgcaacg cgccgcgcgt taccgggtcc agtgcgccaa aaggttcatc
    50701 catcagtaag acttgcggat cggcagccag tgcgcgcgcc actcccacac gttgctgctg
    50761 accaccggaa agctgatgcg gataacgctc acgcaaattt gactccagcc ccagtagcgt
    50821 cattaattcg tcgatacgat cgtcaatccg tgcccgcgac catttttgta attgcggcac
    50881 ggtagcgatg ttttgcgcca cgctccagtg ggggaacagg ccaatagatt gaatggcata
    50941 gcccatccgg cggcgcaact ccagtactgg cagcgagcga atttcttctc cggcaaagcg
    51001 gatctctccg ctgtcatgtt ccaccaggcg gttaatcatt ttcaaggtgg tggatttgcc
    51061 ggagccagat gtgccaatca gcaccgaaaa actcccttcc tgaaaattga gattaagatc
    51121 gttaacggct ttttgtgcgc caaacagttt gctgacatgg ctaaattcaa tcattacgtt
    51181 tcaccttcag cagtgcgata agcaaatcga acagggcatc gatcagcacc gccagaacaa
    51241 ttaccgggat cacccccagc aacactaaat caatggcgct gcttagcagc ccctggaaaa
    51301 ccagcgcacc aaaaccgcct gcgccgatta acgccgcaat caccgccata cctacagttt
    51361 gcaccatcac cacccgcagg ctgcgcagaa ataccggtaa cgccagtggt aactgaacat
    51421 gcaggaatcg ctgcgccccg ctcatgccca tcgctctggc gctctccagc acatcgcgcg
    51481 ggatctggtt caaaccgact accacgccgc gcaccagcgg cagcaaggca tagagcacca
    51541 gcgcaatcag tgcgggtgtc attccggttc ctgctatgcc gagcttcccc agccacggaa
    51601 aggccgtcac cagcgcggca agcggcgcaa tcaacaggcc aaagagcgcc accgaaggca
    51661 cggtctgaat gacattgagc agagaaaaaa ttgccccctg ccgcgcagtg gaaaagtagc
    51721 accagatgcc caacggcaca ccaatcacta acgcaggcag caccgcacca aacagcaacg
    51781 tcagatgttg tgccagcgcg tcgtcaaaca catcctgacg gttggcgtat tctttcatta
    51841 gtgagagatc gttaagcgtg ccggagtaca gcaaccacag cggaataatg gcaatctgca
    51901 tatgcaacaa ccagcgccac agcggatgcg tggagattcg gcggatggca tcgctacagg
    51961 ccagcaatgc cagcgccgca gccagccaga aaccactgcc gaggctggta cgcgccagcg
    52021 cactgccatt ttgcgccagt tgggtcgccg cctttccagc tccccacacc aacaatacga
    52081 agacgaattg cgccagaatg agtgcacaaa tgctgccttt tttagcgggg acaaaacagg
    52141 ctgtcagcca ggcgcaacca acgcccacca gcatccagat cgtttgcggc cacagttgcc
    52201 agagatgacg cccttcaccc gagactaaac gattaggcgc gtagctgata aacggcagcg
    52261 ctgctgcgat tgccgtcagc aacagcagca gcgccagaac aggattaata cgtagataag
    52321 tcacgggaaa ttacttcgcc cacccttttt gtttcaggta gtcggcagcc acttttttgg
    52381 catccagtcc ttccactgca atgctggcat tcagttgctg caatgttttt gcatcgaggc
    52441 tggcgaagac tggctgtagc cactgtgcca tttgcggata ctccttcaac accgattcac
    52501 gcaccactgg tgcaggcgca tagataggtt gcacgccttg cggatcgctt aaggtttgca
    52561 gccccagcgc cgctaccggg ccgtcagtgc cgtaagccat tgcagcatta acgccagagg
    52621 tttgctgggc agcggctttg atcgtcaccg ccgtgtcgcc accagccagt gacagcaact
    52681 gatcctgacc gagcttaaag ccataggctt tttcaaacgc gggtaacgca tcggcgcgtt
    52741 cgataaactc tgccgaggct gccagtttga aggtgccgcc ctcttgcaga taacgactca
    52801 ggtcggcaag cgaagtgagt ttatttttct ctgccacatc ctgacgcacg gcgatagtcc
    52861 aggtgttatt tgcaggcgcg ggcgtcagcc agattaactt gttgtgctcc gaatcgagct
    52921 ttttgacttt ctcgtaacct tgctgcgcgt ttttccacgc tgcatcgttt tcatctttaa
    52981 agaagaaagc gccattgccg gtatattccg gatagatatc cagttcaccg gaagtaatcg
    53041 ccccgcgcac cacaggagtc gttccgagtt gcactttatt caccgtcggt acgccgtggc
    53101 tttccagcac ctgcaaaatg atattgccga gtagcgcacc ttcggtatcg atttttgaac
    53161 cgactttaac gggggaagcc gcctgtagcg gcaggctcac ggctgccaac ataaccagtg
    53221 aacctgccca gagctttaag agtggcatga tgctttcctc attcttttac tgttgttttc
    53281 agcgaattaa gagaaaagca tagttgataa tggcggggtt agcttgagcg gaaggattca
    53341 gttgcagaat cagataaata cttaagaggc atattcggtc cggcgtttcc tgccggatgc
    53401 ggcgcgagcg ccttatccgg cctacaaagg gcgcaaacgt cgcgccctta ctaaagcatt
    53461 acagcaactc aaactcgcct ttcttaacgc gtgcggaatc agtgccgata aatacattga
    53521 acttgccagg ctcggcgtca tatttcatct gttgattcca gaacttcagc gcctcaatat
    53581 cgatcgggaa gctgacagtc tgagtttcgc ccggtttcag ggtgattttc tcaaagcctt
    53641 tcagctgttt cacagggcga ctcatggaag ccgtcacatc ctgcaagtac atctgcacta
    53701 ccgtggcccc ctcgcgctta ccggtgttcg tcacctgcac gctggcagtc actttgccgt
    53761 cacgcttcat ggtcggcgca gaaagtttca catcagagac ggtgaaagtg gtgtagctca
    53821 gcccatagcc gaacggatac aacgccccgt tagcttcatc aaaataacgc gaagtgtatt
    53881 tgttcggctt gtcggcatta tacgggcgac cggtattcag atggctgtag tacaccggga
    53941 tctgcccgac agaacgcggg aaggacattg gcagcttgcc ggacgggttg taatcgccaa
    54001 acaatacatc ggcaattgca ttaccgcctt cagtccccgc aaaccaggtt tccagaatcg
    54061 catcagcctg ctgatcttct ttcaccagcg ccagcggacg cccgttcatc agcaccagca
    54121 ccagcggttt accggtggct ttcagcgccg caatcaagtc acgttggctt tgcggaatag
    54181 tgatatcggt ccggctggag gcttcgtgcg ccatcccctg tgcttcaccg actacagcca
    54241 ccaccacatc agattgtttc gccgtctgca ccgcttcatc aatcatctct tgcggcgaac
    54301 gcggatcgac tttgaccgct tcttcatact gattcaggaa atcgataatg cctttgtcac
    54361 tggtaacgtt cgcccctttg gcatacagca ctttaccgtt ttcaccgacg gaatttttaa
    54421 tcccggtcag tacggtcacg gattgatcgg caacaccggc tgcggaccag ctgcccatca
    54481 cgtcacgttt actgtccgcc agtggcccaa ccaccgcaat ggtggccgat tttttcagcg
    54541 gtaacgtttc gagacggttt ttcagcaaca ccaggctttc gcgcgccact tcacgcgctt
    54601 ctttacggtg caggcggctt tcggcattgg tatccaccgg gtcagactct ttcggcccca
    54661 aatggctgta tgggtcgtta aacaatccca tatcatattt aacgttcagt acatggcggg
    54721 cagcatcgtc cagctcttcc atcgtcactt tgccggagtt gatcaaccca ggcagatact
    54781 tcgagtaata ctcgtcgctc atactcatgt tgattccgga tttcagcgcc acgcgcaccg
    54841 catcttccgg gtctgccgcc gtgccatgtt taatcagctc tttgattgca ccgtgatcgg
    54901 aaacggtgat gcctttaaag ccccactggt cgcgcagaac atctttcagc agccaggaat
    54961 cggaggtggc tggcgtgccg ttcagcgagt tcagcgccac catcaccgcg ccgctgcctg
    55021 cgtccagccc cgctttgtac ggcggcatat aatcattaaa caggcgctgc ggactcatat
    55081 cgacggtgtt gtactcttta ccgccttcta ccgcgccgta tgcggcaaag tgtttgacgc
    55141 tggtcatcac cgagtagcga tctgccgggc ttttaccctg catcgcttcc accatggttt
    55201 tacccattgt tgaggtgaga tacgtatctt cgccaaaacc ttcggaagca cgtccccagc
    55261 gcggatcgcg cgagacatcg accatcggtg cccaggtcat attcaggcca tcatctgccg
    55321 cttcataagc agagacacgt ccgaccgttt tcactgcatc gaggttaaaa gacgaggcca
    55381 gaccgaggct aatcgggaac accgtgcgct gaccgtgcag cacgtcgtaa gcaaagaaaa
    55441 gaggaatttt caggcggctt aattccatca cctgatcctg catggcgcgg atatcctgac
    55501 gggttacggt gttgaaaatc gccccaacct gaccgtcttt gatcatctcg cggatcgcct
    55561 ctttcgggtt atccgggccg acgctgatta agcgcagctg accaattttc tcatcaactg
    55621 tcattttctt aagcagttcg gtgacgaacg catcccgcgc ttcgggcgtt aatggatggt
    55681 tgccgaataa atcatccgcc agtgctggct gcagggccag actcaccgcg attcctactg
    55741 aacatagcca tttcatatgg atttttcttc ctctgttgcc cgacgaggca gcgaaaatgg
    55801 tgcaaaaacc gtagtttgcc ataagcatga tggagagaga aaaagaatgc tcagtttatt
    55861 gtctgaattt tcaaaatatt cactcgctga attgtcatac aaggcgctat tctagtttgt
    55921 gatatttttt cgccaccaca aggagtggaa aatgtcttcc atgacaacaa ctgataataa
    55981 agcctttttg aatgaacttg cccgtctggt cggtcattca cacctgctca ccgatcccgc
    56041 aaaaacggcc cgctatcgca agggcttccg ttctggtcag ggcgacgcgc tggctgtcgt
    56101 tttccctggc tcactactgg aattgtggcg ggtgctgaaa gcctgtgtca ccgccgacaa
    56161 aattattctg atgcaggctg ccaatacagg cctgaccgaa ggatcgacgc caaacggtaa
    56221 cgactatgat cgcgatatcg tgatcatcag caccctgcgt ctcgacaagc tgcacgttct
    56281 tggcaagggc gaacaggtgc tggcctatcc gggcaccacg ctctattcgc tggaaaaagc
    56341 cctcaaaccg ctgggacgcg aaccgcactc ggtgattgga tcgtcgtgta taggcgcatc
    56401 ggttatcggc ggtatttgta acaactccgg cggctcgctg gtgcaacgtg gcccggcgta
    56461 taccgaaatg tcgttattcg cgcgtataaa tgaagacggc aaactgacgc tggtgaacca
    56521 tctggggatt gatctgggcg aaacgccgga gcagatcctt agcaagctgg atgatgatcg
    56581 catcaaagat gacgatgtgc gtcacgatgg tcgtcacgcc cacgattatg actatgtcca
    56641 ccgcgttcgt gatattgaag ccgacacgcc cgcacgttat aacgccgatc cggatcggtt
    56701 atttgaatct tctggttgcg ccgggaagct ggccgtcttt gcggtacgtc tagatacctt
    56761 cgaagcggaa aaaaatcagc aggtgtttta tatcggcacc aaccagccgg aagtgctgac
    56821 cgaaatccgc cgtcatattc tggctaactt cgaaaatctg ccggttgccg gggaatatat
    56881 gcaccgggat atctacgata ttgcggaaaa atacggcaaa gacaccttcc tgatgattga
    56941 taagttaggc accgacaaga tgccgttctt ctttaatctc aagggacgca ccgatgcgat
    57001 gctggagaaa gtgaaattct tccgtccgca ttttactgac cgtgcgatgc aaaaattcgg
    57061 tcacctgttc cccagccatt taccgccgcg catgaaaaac tggcgcgata aatacgagca
    57121 tcatctgctg ttaaaaatgg cgggcgatgg cgtgggcgaa gccaaatcgt ggttggtgga
    57181 ttatttcaaa caggccgaag gcgatttctt tgtctgtacg ccggaggaag gcagcaaagc
    57241 gtttttacac cgtttcgccg ctgcgggcgc agcaattcgt tatcaggcgg tgcattccga
    57301 tgaagtcgaa gacattctgg cgttggatat cgctctgcgg cgtaacgaca ccgagtggta
    57361 tgagcattta ccgccggaga tcgacagcca gctggtgcac aagctctatt acggccattt
    57421 tatgtgctat gtcttccatc aggattacat agtgaaaaaa ggcgtggatg tgcatgcgtt
    57481 aaaagaacag atgctggaac tgctacagca gcgcggcgcg caataccctg ccgagcataa
    57541 cgtcggtcat ttgtataaag caccggagac gttgcagaag ttctatcgcg agaacgatcc
    57601 gaccaacagc atgaatccgg ggatcggtaa aaccagtaaa cggaaaaact ggcaggaagt
    57661 ggagtaaaaa ttacggatgg cagagtatcg ccatccgaat tcacttaatc gttctgtgcc
    57721 gtctgccccg ccgccgccat ttgggcggct ttttgttttt tatagctcaa cgctgctgcc
    57781 ggcacaggca tcactttacc ggtttcaatc caggtacgca ggcggctggc atcggcaaaa
    57841 tgggtatatt tgccaaacgc gtccatcact accagcgcca ccggtttatt attgataacc
    57901 gtacgcatca ccagacaatg gcccgccgca ttggtaaagc cggttttggt taactgaata
    57961 ttccagttat cgcgatacac cagatgatta gtattgcgga acggcagcgt atacgtcggg
    58021 ttagagaagg ttgccatatc ttcccgggta gtacttaact gcccgatcaa cggatattgt
    58081 ttgctggcaa tgagcagttt ggttaagtca cgggcagttg aaacgttatg caccgacaat
    58141 ccggtaggtt caacaaagcg cgtgttgttc attccgagcg atttcgcttt cgcattcatt
    58201 gccttaataa aggctttgta accaccggga taatggtgcg caaggcttgc cgccgcgcgg
    58261 ttttctgaag acatcagcgc cagcaacagc atatctttac ggctgatttc gctattcagt
    58321 cgtacgcgcg aatagacccc tttcatctcc ggcgtctggc tgatatccac ttttagtttt
    58381 tcatccagcg gcagtcgtgc atccagcaca accatcgcgg tcattaattt gctgatagac
    58441 gcaattggac gcaccagatc cgggtggttc gaatagatca ctttgttggt attcagatca
    58501 acaatcatcg cgctaccgga ggcaatttcc ggttgtgaag cggcggtagc ggctgccgtt
    58561 ttcgcaacgg cctgcggtgc caaaggcaca gccagcatca gggccaggct aaataaagaa
    58621 actcgaaatt tcggcatgat gagcattcag atagtggttc acgcgcacgg gttgcgcacc
    58681 gccggagtaa ggatttactg aggctagcga cgccatcata acgagcaaaa agtgcgatcg
    58741 tcaaaggaga atcgtgagga aatgctgcat tgctgacatt tacgccagca atgcaatgtc
    58801 aaagaacttt ctagaacagg cgatacccgt agccccatag tataacggtt agggcgagca
    58861 gcacttccag taccagcacg ccaatcgcca gcgtcgaact ggagaagcta aggccttcct
    58921 ctttgttgat attcaggaag ctcggaatac caaggtaaag caggtagccg gtgtaaaaca
    58981 gcgccaccgt gccgaccagc gcacacaacc agaccagcgg ataaagcgcc accagaccgc
    59041 ttaaaaacag cggagttgca acgtagcccg cgaagaccat gcagtgcgca agtgacggac
    59101 gctgcgggta attgcgcgcc atccaccaga tgacccgccc catcaccgcg accccagcca
    59161 gcataacgcc gtaaaacaag acagccagcg ccagtccggt aaaccaggat aacttcagga
    59221 tagtgccatc gccaaaattc cagccaatct gtgtagtgcc aatgaaggcg caaatcaccg
    59281 gaatcgccgc catcagcaaa acgtggtggg tgtaatggtg agaaatcgtt tcgttttcgc
    59341 gattaatcac ctgcatttca cgatcgggat gggaaaacag tccccagaca tggctcatac
    59401 cgcccccttg ttgtgagttc atgaacctga cagttcaagt ataagtcagc ttgtgattat
    59461 tttttgttcg cccatgtaat tttcactgtc tgatgaacgt cctttttcag cgtgaatgat
    59521 tcacagggtg tatgcttact ggcaaccaaa gggagacaga ctggcctatg gatctcaata
    59581 cacttatctc acaatatggt tatgccgcgc tggtgatcgg tagcctggcg gaaggtgaaa
    59641 ccgtgacttt gctgggaggc gttgcggcac atcaggggct attaaagttc ccgctggtgg
    59701 tactttctgt ggcgtttggc ggcatgattg gcgaccaggt gctttatctg tgcgggcggc
    59761 ggtttggcgg caagctgtta cgccgtttct cgaaacatca ggataaaatt gagcgggcgc
    59821 agaaacttat ccaacgccat ccgtatctgt ttgtcattgg tacgcgcttt atgtatggct
    59881 ttcgggtgat tggcccgacg ctgattggtg ccagccagct gccgccgaaa atctttctgc
    59941 cgctgaatat tctcggcgca tttgcctggg cgttgatttt taccactatt ggttacgctg
    60001 gtggtcaggt gattgcgccg tggttgcaca atctcgacca gcatttgaag cactgggtct
    60061 ggttgattct ggtcgtggtt ctggtggtgg gcgtgcgctg gtggctgaaa cggcgcggga
    60121 agaaaaagcc ggatcatcag gcgtaaaacc attgccctgg gtaaggcgtt cgcgccgcat
    60181 ccgacatccg gtgcaccatg cctgatgcga cgcttgtgcg tcttatcatg cctaccaaaa
    60241 ttttacccat tgaaataacc acgcacctca ctgcgctatt ctgggttgaa ctgcggattc
    60301 gccaacataa agccgccatc cactatcaac gactgcccgg tggtgtaatt tgcgccctct
    60361 gagcacagcc acgctaccag gctggcaatc tcatgcgttg cgccaaaacg ccgcagagga
    60421 atcgaaggct ccgcgtcggg cttcacgtcg ctgtcatcca tgccattcat tggcgtggcg
    60481 atcgccccag gcgcgactgc gttcaccaaa atcttatgcc tgaccagctc cagcgccatc
    60541 gttttggtta acccgccgag cgcatgttta gcggctgtgt aagcgctggc atccggcagc
    60601 ggcgtatgtt catgtaccga cgtaatgttg atgatgcgac cgccctgccc ttgtttcacc
    60661 atctggcggg ccgcaatttg tgagcataaa aatgcaccat cgacatcaac ggtaaaaatc
    60721 ttgcgccact catcgaaagc catatcaaga aacggcgctt tggtcattgc gcccgcatta
    60781 ttcaccagca catcaatacg ccccagccgt tgaatgagtt tctccagcgc ctgcgcacct
    60841 tctggcagtt taccgagatc cagctgcacg atctccgcac gtacgccgtg gctaactacc
    60901 tcacgcgcgg tatcttttgc cccttcttca tctgagtgcc aggtaatgcc aatatcaaac
    60961 ccctgctgcg ccagtaataa cgcgcactct ttgccgatcc ccgaatcgga ggcggtaata
    61021 atcgcaacct gtgccatcga gttctccact taacgctgaa taaacgttaa gtatagaagg
    61081 cgcatatcat cagcgtttgt aacccccgcc caacgcacca gtgagttgaa tggaagcatc
    61141 cagccactgc ccttgcaata acaggccatt ggcccgctca cgcagcgcgg ggattctggc
    61201 ttcgctgacg cgggaaccag caatgatgcc cgcgttaaag cgcgcctgcg caagacctac
    61261 cacacgcaag gcatcgcgct caatttgcgc ctgatgctgg tttttctccg caagtgtctg
    61321 aacctgactg gctgcccgcg ccacgtcatt caccgcttca accaccgctt tgttgtagct
    61381 ggcgatagac aagttgcttc cggcttttgc gatatcgaga ttggcgttaa gacgaccact
    61441 atcgaaaatg ggtagcgtca ggcctgccgt aacgcccatt tgctgcgcgg aatgacggaa
    61501 cagatcgctt aagtgcaacg catcctgttg caggaaggcc atcaggttga tgtcaggata
    61561 aaatgccgct tttgccgcat caatggtgct tagcgatgac tcaacgtacc agtgcgccgc
    61621 ctgcaaatct gcccgccggg ccagtaagga gtaccccagt tcatcaggaa gctggcttgc
    61681 cactttcggc aacgcgaccg gtttaagctt caatgacttt gtctggttat ttgtaagtgc
    61741 gcttaaccgt gcctcaataa ttttcatttt ccccgcgaca tcgttgagct gctgccgggt
    61801 tttgctggca ttaatatcgg tttccacacc gtcaactgaa gaagtaatcc cgttctgata
    61861 tagctggcga tcggtcgcga taatggtgtt ctgctctttt tctatttgct gcaagaccgt
    61921 gtttaacgcc gcctgggttt gccactccca gtacaggcgg gctacgctgc cagccagcaa
    61981 ttggcgggtt tgctcgcgtt ccgccgcccg tgctttaacc gtacccaggc gggcagtaac
    62041 ctccgcccga ttctttcccc agatatcgag atgccagccc gccgttaagc caaaagttcc
    62101 gttggtgtac cacggaccgg tcgtacctgc ggccggatcg ttcagagcaa acggccccat
    62161 taagccttct gccgacattt tttgccgctc catatccgca gaaaagtcga tctgcggacc
    62221 atcctgagta gcaattgcct tcgcctgggc ttcagctagc tgaatgcgct gttcagccac
    62281 ctgcatatcc ggtgcgttct gtagtgcatt gttaattaag gaagtgagtt gattatcgtg
    62341 atactccagc caccattggc tgtctggcca accatttttc agcgccgtgg gtaatgcggt
    62401 gtcaacttgt gcagcgggcg tttgctggct taacgcctgg cgggtttcat gcataggcgc
    62461 acacccggcc agcatcagta acagcggaaa acaggcgatg gcgggataaa aggaatcacg
    62521 attcatgggg gaataatcag gtaagaaaag gtgcgcggag attaccgtgt gttgcgatat
    62581 attttttagt ttcgcgtggc aatacatcag tagcaataaa acgacatatc cagaaaaata
    62641 tacactaagt gaatgatatc ttccgattta tcttaatcgt ttatggataa cggcaaaggg
    62701 cttcgttttt tcctatactt attcagcact cacaaataaa ggaacgccaa tgaaaattat
    62761 actctgggct gtattgatta ttttcctgat tgggctactg gtggtgactg gcgtatttaa
    62821 gatgatattt taaaaatcag atatggcata taagttgtca ggtcaggaac tagatatttt
    62881 gtgtacttga tttgcaaaca gctccggtgt tggtggcgtc aaaatcgctg aagcgttccc
    62941 cgaaggccgg ggcagcccac atggatgtgg gctgagggcg cgtcttacaa ggacgtttcc
    63001 tcgcgcccga cccggtagcc gaaggggata agctgaaggt accgcgcagc ggcgattttg
    63061 ttcgccagag cccgggggtg cagggggagg aggcgattgt cctccccctg cgcgctcctt
    63121 gcgccagtgg caatatgtgg cttagttcat gaaaggagcg caacaagatg atgaagctga
    63181 ataagcgatt cattgtctct gataagctgc gattccacta ttatcgcagc ttatcgatat
    63241 caattgcctg aatagccctt gcaatatcag gggaattatt caacacccga acatgctgaa
    63301 ataatcccgt tgcttcatcg tattctttac gcaaataact caaccactgt ttaatccgcg
    63361 caacgtgata taacccggta tcgccctgct tttccagacg ggtatatttt tgcagcaaag
    63421 caaccacctc cggccacggc attcgcggtt cgttatattt tactacccgg ctcaggttgg
    63481 gaatattgag cgccccgcga ccaatcatca ctgcgtcgca gccgctgatc gccatgcatt
    63541 gttgcgcgct ctgccagtcc cagatttcac cgttggcaat caccggaata ttcagccgct
    63601 ggcgaatatc gccaatcgcc tgccagtcaa tatgctccgc gcggtaaccc tgctctttcg
    63661 tccgcccatg caccaccagc tccgtagcgc cagcctgttg aaccgcatcg gcgatttcaa
    63721 atttcttctc accgctgtcc cagcccagac gcactttcac gctgacgggc aaatgcgccg
    63781 gtacagcttc acgcatcgct tttgcaccct ggtagatgag ttcaggatct ttgagtaacg
    63841 tcgcgccgcc gccgctaccg ttaaccgttt tcgacgggca gccgcaattg agatccacgc
    63901 cccaggaacc taactccacc gcacgggcgg cgttctctgc cagccattgt gggaactgac
    63961 ctaacaactg cacgcgcacc agcgtaccag atggtgtccg gctggcgttt tgtagctcag
    64021 ggcaaatgcg atgaaagact tttaccggca gcagttgatc caccacgcgg acaaactcgg
    64081 tgatgcacag atcgtagtcg ttaacttcgg tcagcaattc acgcaccaga gagtcaagca
    64141 ctccctccat cggtgccagt aacacacgca tatcatcacc cgcaaaataa tgaggcgcta
    64201 tgttagcgcc tatggtcagc ggattaaagg tctacaaaga gggattgctg caaactgcaa
    64261 tccctctcta tgcttgatgt atgcctgagt tcgttgcgca ttgcgtaatg ccggggagcg
    64321 aaaaaataag cgctgatttc ttaatgtgat cggtagcacg ttttacgaat taattgtatg
    64381 atgaatccat ctcatctggg gtgttgatta tgagtaagac actgaacatt atctggcaat
    64441 atttacgcgc tttcgtcctg atttatgcct gcctgtatgc aggcattttc attgcttccc
    64501 tgctaccggt aaccattccg ggcagcatca tcgggatgct gatcctgttt gtcctgctgg
    64561 ccttgcaaat tcttccggcg aaatgggtca atccggggtg ctacgtactg attcgctata
    64621 tggcgctatt gtttgtgccg attggcgtag gcgtcatgca atattttgat ttgctccgcg
    64681 cgcagtttgg cccggtagtg gtttcctgtg ctgtcagtac gctggtggtt tttctggtgg
    64741 tgagctggag ttcacaactg gtacacggtg aacgtaaagt cgtaggtcag aaaggatcag
    64801 aagaatgatg gcgaatatct ggtggtcatt accgctgacg ttgattgtct tttttgccgc
    64861 ccgcaaactg gcggcacggt ataagtttcc cctgcttaac ccgttgctgg tagcaatggt
    64921 ggtgatcatt ccttttttaa tgctgaccgg catctcttac gacagctact ttaaaggtag
    64981 cgaagtgcta aacgatctgc tgcaaccggc ggtcgtcgcg ctggcctatc ctttatatga
    65041 gcagctacac cagatccgcg cgcgctggaa atcgatcatc accatctgtt ttatcggcag
    65101 cgtggttgcg atggtgacgg ggacttccgt ggcattgttg atgggcgctt caccggaaat
    65161 cgccgcgtca atcctgccga aatcagtcac cacgcctatt gcaatggcgg ttggcggcag
    65221 tattggcggt attccggcaa tcagcgcagt ttgcgtgatt ttcgtcggca tcctcggcgc
    65281 ggtatttggc catacattgc ttaatgcgat gcgtattcgt accaaagctg cgcgcggtct
    65341 ggcaatgggg actgcctcgc acgccctcgg tacggcgcgc tgcgccgagc tggattatca
    65401 ggaaggtgca tttagttcgc tagcgctggt gttatgcggg ataattactt cgctgatcgc
    65461 accgttcctt ttcccgatta ttctggcagt aatgggctaa aatttgcgat gcgtcgcgca
    65521 tttttgatgt aagtttcacg cgttgcataa ttaatgagat tcagatcaca tataaagcca
    65581 taacgggttc gtaaactgtt atcccattac atgattatga ggcaacgcca tgcatccacg
    65641 ttttcaaacc gcttttgccc aacttgcgga taacttgcaa tctgcactgg aacctattct
    65701 ggcagacaag tacttccccg ctttgttgac cggggagcaa gtctcatcgc tgaagagcgc
    65761 aacggggctg gacgaagacg cgctggcatt cgcactactt ccgctggcgg cggcctgtgc
    65821 gcgtacgcca ttgtcgaatt ttaatgttgg cgcaattgcg cgcggtgtga gcggaacctg
    65881 gtatttcggt gccaatatgg aatttattgg tgcgacaatg cagcaaaccg ttcatgccga
    65941 acaaagcgcg atcagccacg cctggttgag tggtgaagaa gcgcttgcag ccatcaccgt
    66001 taactacacg ccttgtggtc actgccgtca gtttatgaat gaactgaaca gcggtctgga
    66061 tctgcgtatt catctgccgg gccgcgaggc acacgcgctg cgtgactatc tgccggatgc
    66121 ctttgggccg aaagatctgg agattaaaac gctgctgatg gacgagcagg atcacggcta
    66181 tgcgctgact ggtgatgcgc tttctcaggc ggcgattgca gcggcaaacc gttcgcacat
    66241 gccttacagt aagtcgccaa gcggtgtcgc gctggaatgt aaagacggtc gtattttcag
    66301 tggcagctac gctgaaaacg ccgcattcaa cccgactctg ccaccgttgc agggagcgtt
    66361 aattctgttg aatctcaagg gttatgatta cccggatatc cagcgcgcgg ttctggcaga
    66421 aaaagccgat gcgccgttga ttcagtggga tgccacctcc gcaacgctga aagcgctcgg
    66481 ctgtcacagt atcgaccgcg tgcttctcgc ttaagcctgg tgccggatgc ggcgtgaacg
    66541 ccttgtccgg cttgccagcc ctctcctggt gtcgaaaatc ccggcaaaca gtttgccgtt
    66601 tcttgcgcaa aaccagcggg taaagtagcc tgatggaaat ttcccttaga tcgagtctcc
    66661 tgcatgttaa agcgcgtgtt cctcagcctg ttagtcctga tcggcttgct gctgttgact
    66721 gtgctcggcc tcgatcgctg gatgagctgg aaaaccgcgc cttatatcta cgacgaattg
    66781 caggatctcc cctaccgcca ggtcggtgtg gtgctcggaa cagcaaaata ttatcgtact
    66841 ggcgtaatta atcagtatta tcgctaccgc attcaaggag cgattaatgc ctataacagc
    66901 ggtaaggtaa attatctatt actgagcggc gataacgcat tgcaaagtta taatgagccg
    66961 atgaccatgc gcaaagattt aatcgctgct ggtgtcgacc catcagatat tgttctcgat
    67021 tacgcaggct ttcgtacgct ggattccata gtgcgtacac gcaaagtttt cgatactaat
    67081 gatttcatta ttatcaccca acgtttccac tgtgagcggg cattatttat tgcgctgcat
    67141 atggggattc aggctcagtg ttatgccgta ccgtcaccga aagatatgct gtcagtacgt
    67201 attcgcgaat ttgccgcccg tttcggagcg ctggctgacc tttatatttt taaacgtgaa
    67261 ccgcgttttt tagggccgct ggtccctatt ccggctatgc accaggtgcc ggaagatgcg
    67321 caggggtatc ccgccgtcac acccgaacag ttacttgaat tacaaaagaa acaaggaaag
    67381 tagttatgga tgtacagcag ttttttgtcg ttgccgtttt tttccttatc ccgatatttt
    67441 gtttccgcga agcatggaaa ggctggcgcg caggcgcgat tgataaacgg gttaaaaatg
    67501 caccggaacc ggtgtatgtc tggcgagcaa aaaatcccgg actctttttc gcttatatgg
    67561 tggcatatat cggcttcgga attttatcta tcggcatgat tgtttatctt attttctatc
    67621 gttaatattt tctcttttct gttaattatt gagaataatt attacttcac tcaataagct
    67681 gcggatataa cattctgaac cgcagctatt tgtgaatcct ttcacagtat aaatttcccc
    67741 acgcgcatag ccttaatatc agcacgcaat atttatactc taaataattc gagttgcagg
    67801 aaggcgacaa gtgagtgagt ccccaggagc ttacataagt aagtgactgg ggtgagcgaa
    67861 cgcagacgca gcacatgcaa cttgaagtat gacgagtata tttagcgttc gccttaatta
    67921 ctcatagcat taaggaagat cacatgccgc aacaaaatta tctggatgaa ctcactccgg
    67981 cttttacgcc tttactggcg attaaagaag cctctcgctg tttattatgt catgacgctc
    68041 cctgtagtca ggcttgcccg gcacagaccg atccggggaa atttattcgc tcaatctact
    68101 ttcgtaattt taaaggcgct gccgagacaa ttcgcgaaaa taatgccctc ggtgccgttt
    68161 gtgccagagt gtgcccgacg gagaaattat gtcaaagcgg ttgtacccgt gccggtgttg
    68221 atgctcccat tgatatcggc cgcttacagc gttttgttac tgattttgaa caacaaaccg
    68281 ggatggaaat ttatcagccc ggtactaaaa cgctcggcaa agtcgcgatt attggcgcag
    68341 gtcctgccgg attgcaggcc agtgtaacac tgacaaacca gggttatgac gtcacgattt
    68401 atgagaaaga agcgcacccc ggtggctggt tgcgtaacgg tattccgcaa ttccggttac
    68461 cgcaatcagt gctggatgca gagatcgccc gtattgaaaa aatgggcgtg accattaagt
    68521 gcaacaacga agtcggtaac acactcaccc ttgagcagct gaaagcagaa aaccgcgcgg
    68581 tactggtcac cgtggggtta tcgagcggtt ccgggttatt gctgtttgag catagcgacg
    68641 ttgagattgc cgtggacttc ctgcaacgtg cacgacaggc gcaaggcgat atcagcattc
    68701 cacaaagcgc attaattatc ggcggcggtg atgttgcgat ggacgtagcc agcacgctga
    68761 aagttctcgg ctgtcaggcg gtaacctgcg tagcgcgtga agagttagat gagtttccgg
    68821 caagcgaaaa agagtttgcc agcgcccggg agctgggcgt ttcgatcatc gatggattca
    68881 cgccagtagc cgtggaaggc aataaagtca cgtttaagca tgtacggtta ccgggcgaac
    68941 tgacgatggc ggcagataaa attattctcg ccgtcggtca gcatgccaga ctggatgcct
    69001 ttgcggagtt agagccgcag cgtaacacta tcaatacaca aaattatcag acccgcgatc
    69061 cgcaagtctt tgctgcgggc gatattgttg agggtgacaa aaccgtggtc tatgccgtga
    69121 aaaccgggaa agaagccgcc gaggcgattc atcactattt agagggagct tgctcatgtt
    69181 aacgaaagat ctttcgatta ctttttgcgg cgtgaagttt cccaacccgt tctgcctctc
    69241 ttcttcgccg gtaggcaact gctatgagat gtgtgccaaa gcctacgaca caggttgggg
    69301 cggtgtggtg tttaaaacga tcggcttttt tatcgccaac gaagtctcgc cgcgttttga
    69361 tcatctggtg aaagaagata ccggttttat cggcttcaaa aatatggagc agattgctga
    69421 acatccgttg gaagagaatc tggccgccct gcgtcggctg aaggaagatt acccggacaa
    69481 agtattgatc gcttcgatca tgggggaaaa tgagcagcaa tgggaggagc tggcgcgcct
    69541 ggtgcaagaa gctggcgcgg atatgatcga gtgtaacttc tcctgtccgc aaatgacttc
    69601 tcatgcgatg ggtagcgatg tcgggcaaag cccggagctg gtagaaaaat attgtcgggc
    69661 agtgaaacgg ggttccacgc tgccaatgct ggcgaagatg acgccgaata tcggtgatat
    69721 gtgcgaagtg gcgctggcgg cgaagcgcgg cggcgcagat ggcattgcgg cgattaacac
    69781 cgttaaatcc atcaccaata tcgatcttaa tcagaaaatc ggtatgccga tcgttaacgg
    69841 aaaatcgagt atttccggat attccggtaa agcggtaaaa ccgatcgccc tgcgcttcat
    69901 tcagcagatg cgcacccatc cagaactgcg cgatttccca atcagcggta tcggcggcat
    69961 tgaaacctgg gaggatgcgg ctgagttttt attgctcggc gcagcaacgt tacaggtgac
    70021 caccggcatc atgcagtacg ggtatcggat agtggaagat atggcaagcg ggttgtcgca
    70081 ttatctcgcc gatcagggat ttgattcgct gcaggagatg gtaggtctgg cgaataacaa
    70141 tattgtcccg gcggaagatt tagaccgcag ttatattgtc tatccccgta tcaatcttga
    70201 taaatgtgtt ggctgtggac gctgttatat ttcctgttac gacggcggtc accaggcgat
    70261 ggaatggagc gagaaaaccc gcacaccgca ttgtaatacc gagaaatgtg tgggttgtct
    70321 gctttgtggt cacgtctgcc cggtgggttg tattgagctc ggggaagtga agtttaagaa
    70381 aggcgagaaa gaacacccgg taacgttgta aaaccagaga cgcatccggc atttggcacc
    70441 gattgccgga tgcagcgcat ccggcaatat ccacaatcac atcacttctt acgcgcgtat
    70501 ttcagtgaat ccagcgctac ggcgaagata ataatcgccc ctttgatgat gtactgccag
    70561 tatgggttaa cgccgatata cgtcaggcca tagttgatga cggtaaaaat aattaccccg
    70621 gtcaccacgc caatcaccgt ccccacaccg ccgctgaacg atacaccgcc taccacgcac
    70681 gccgcgatag catccagctc atacataaag ccgaggttgt tggtggcaga gccgatacgt
    70741 ccggcttcta acatcccgcc aaaggcatag aacacgccag acaacgcgta gatcatcagc
    70801 aggttcaggc cgacgttgac accagatact tttgccgctt ccgggttacc gccaatggca
    70861 aaaatgttct taccgaagcg ggttttgttc cacaacaccc agacgaacgc caccgcaatc
    70921 aacgcgtaga aggtgatgta agagagacgg aaactcccca gcgcgacaaa gccctgagca
    70981 aaggtagaga agccactgtc aaaaccagaa attggcgacg ccccgacaaa gtcgtaatag
    71041 agcgagttga tgccatagac gatgatcatc gtgccgagcg tggtaatgaa cggcgtcacg
    71101 ttgagataag cgataatcag accgttgatc aaaccgatca ccgcaccaat ggcacagaca
    71161 atcagaataa ccagcgcaat cggcatcgtc gccatttccg ggaacacttt gttggcgtta
    71221 tccatggact gcaataatgt cgcagccacc actgccgcca gccctacctg acgaccagca
    71281 gaaagatcgg tcccctgggt gacaattaac cctgccacac cgagcgcgat aataatacgc
    71341 accgatgact gggtgagaat attacttaag ttcaacagac ttaaaaatgt tgggtcctgg
    71401 aaaataataa tcgccagcaa aactaaaaga acgacgtaaa taccgccctc tttcaggtaa
    71461 gtaagaaaac ttttcttatt taacgcactc atgggaagcc cctaatctta aaggtgcaaa
    71521 gacgcaagac gcagaatttc gttttgcgtt gttgtttttg tatcgacaat tccggaaacg
    71581 agaccattgc tcatgaccag aatacggtct gttatcccta acaactcagg catttcagag
    71641 gagataataa taatcccctt gcctttcttc gccagttcgg caattaactg ataaatttca
    71701 aacttcgccc cgacatcaat accgcgcgtc ggttcatcga gcattaatat ttctggttgc
    71761 gttagtagcc agcgaccaat aatcaccttt tgctgattac caccggagag cgaaccaatt
    71821 tgcgtccgat gacccggcgt ttttacccgc atcgaatcaa tcacccactg ggtatcgctt
    71881 ttcatccgcg agttatccag taaaccaact ttatttttgt agttgcgaat attggaaatt
    71941 aacgagttaa aaccaatatc cagataggca taaattcccg ttgagcggcg ctcctcagtt
    72001 accagtgcaa atccgtggtt tatggcttcg ttggcattat ggttattgat ctgtttgccg
    72061 tgcaacgtaa tggtgccagc cgatttctcg cgaataccaa ataacgtctc aacaatatcg
    72121 gtacgtttcg cccccaccag cccggcaata ccgaggatct cccctttatg cagatcaaac
    72181 gagacatcgc gaatcgacgg ctggcgcagt gacgttaggt tacgcacctc gaggatgact
    72241 tcgcccggct tgttttcttt gtcaggaaaa cgctgattaa gagaacgccc aaccatcatg
    72301 gcgatgatct tgtccatcgt cagtcctgcc agcggttcgg tggcgatcca ctgaccgtcg
    72361 cgcaatacgg taacttcatc acataactgg aagatttctt ccattttatg cgagatataa
    72421 acaataccgc agccgcgctc ttttaattta cgaataatag tgaacagatg attgacctct
    72481 ttttcggtta acgaagaagt cggttcatcc ataatcacaa ttttcgcgtt ataggaaaac
    72541 gctttggcga tttcgatcat ctgcatttgc gaaacggata atgtgccgac gcgcgcacgc
    72601 ggatcgatat caatatccag ttcatcaaaa atcgctttgg tttcgcggta cattttgtcc
    72661 tgatcgacaa acatgccttt ggtgggatat cgccccagcc acatgttatc catcaccgaa
    72721 cgttgtaata ccaggtttaa ctcctggtgt accatcgaaa taccattttc cagtgcctct
    72781 ttggcggaat ggaaatcgat ctctttaccc tggaataaaa tggtgccgga gtctttttga
    72841 taaataccaa acaggcattt taataatgtc gattttcctg caccgttttc ccccattaat
    72901 gcatggatag aatgtggccg gacttttaaa ttaacgttat caagtgcctt aacaccagga
    72961 aaggacttgt tgataccgct catttccaac aagtattccc cggaagacgg agtcgttgag
    73021 ctgaccatat aattttacct tgttggccat acaataaggg cgcagtaaac gactgcgccc
    73081 aatcagtctt atttcttgct gaattcagcc aggttgtctt tatctacgcc aacataaggt
    73141 acgcggacca ctttgttgtc gattttccag ttggtgccat cagccgcacc tttgccatcg
    73201 gccaggtttt tcgccagatc aaaggtcgct ttcgcctggt tgttagcatc gttcagtacg
    73261 gtgcccgcca gtgcaccgga tttcaccagc gccagagctt ctggcagcgc atcgacgcca
    73321 aacaccggaa tgctggactt gttgtgtgct ttcagcgctt caaccgcgcc cattgccatc
    73381 gcatcgttgt tagcaataac cacttcgatt ttgttggcgt tcgggccaga cagccaggcg
    73441 tccatcttat ctttcgcctg agcggtgtcc cacattgcgg tatctaactg taactgttca
    73501 gttttgatgc ctttatcgtt cagctcttta atcacgtaag tggtacgtgc ttctgcatcc
    73561 ggatggcccg gctcaccttt cagtagtacg aactgaatct gaccgtcttt gttcagatcc
    73621 caaccctgat tcgccgccca gtgtttagca atcaaatcgc cctgaataat gccggactct
    73681 ttggaatcag tgccaacgta gtaggctttg tcgtagctat ccagcgcctt acgagacggt
    73741 tctttgttga agaaaaccac cggcacgttt tgcccacgcg ctttctcaat caccgtaccc
    73801 gcagctgccg ggtcaaccag gttgattgcc agtgccttca cccctttcgc cagcaatacg
    73861 tcgatctgat cgttctgctt ggactggtca ttctgagaat cattcatcag cagctgaaca
    73921 tctggcgcgg ctttcgcatc ttgctcaata gctttgcgca ctacagacat aaagttatcg
    73981 tcgtacttat agattgttac accaatgcga gtatcagcag cgtgtgcagc ggcaccgaat
    74041 aacatgctgg ccatcacagc agacagggtt aacaccttct tattcatggt atctccggtt
    74101 tttcttatgc agggtagtgc ttgagataaa tgctcggcgg ggcagtagag ttaatgaagt
    74161 gttactgaac gccgaagctc actttttaaa attcgttctt ccatgcccgg taacgctcca
    74221 gaaaacggct ttaattgttg ttatgacgct attacctcgg tgaaagtgat tattcactgt
    74281 tacatacggg ttacaacgtt aaaacggtgc aatcatagct atcacattgt taagatactg
    74341 tgaaatcact cacagattga aagcggttac atcgcctgat ttgttgagtt agtgatcgcc
    74401 gccgcattct ggcgcgttgc gacagaatga cgacgcacta acgtcggcat aaaacagtgg
    74461 ctggcacgag aatcaatatt gcctgctgcc ccctgcaagg ccagttcggt ggctaattta
    74521 gtcattgaag caatgggata acgcacggtc gttaattgcg ggtcggtgta acgggcgatg
    74581 ggaatatcat cgaaaccgat gattgagaga tgtaacggaa tcgcaatgcc attatctttt
    74641 aatgctgtca gtgcgccagc ggccatattg tcgttataag caaatacagc ggtaagttgt
    74701 agattgcgcc ccagcagttc aaccatcgcc gcctcaccgc ccggcatgtc cggcgtacca
    74761 gtgccaatcc agctttccgg cggaataata tcctgctctt tcaacgcact catccagcct
    74821 gctttacgca tggcgtcatc ttcaatgccg tggctggaag aaagataacc aatacgttga
    74881 tgaccgttat tcagcaacat gcgcgtcgcc attcgggcac cgctgagatt atccaggcaa
    74941 acgcaacgat gggcgtaccc cggcacaacg cggttgatta acaccatacc gggaatgtta
    75001 tccataaatt gcgccagttc atcgtcactc aatgcttttg agtgaacaat caacgcatta
    75061 caacgctggc gaattaacac ctcaatggcg tgacgctctt tttccgcttc atgatagcta
    75121 ttgccgatta gcacgtattt ctgatgctgc tgggcgacca gatccaccgc ttttaccagc
    75181 gcaccgaaaa acgcatcaga aacgtccatc accaccacgc caatggtgtc gctaacctga
    75241 gttgccagcg cctgggcatt ggcgtttggc cgataatcca gctcactcac ggctttcatt
    75301 actgcttcac gcgtgtcggc actgaccagc gtgctgttat tgagcacccg ggaaaccgtt
    75361 gccacagaga cgccagcctg acgcgctaca tcacgaatgg tgatcatatt cactacctgt
    75421 tatgagattg cagtaaatga ctgcttgctg gcggctattt tgtcagcact gaatacagga
    75481 cttcgtgaat cgagtcacag caatggaaac ggttacagcc gttttgttaa cgaatgtgat
    75541 ccagatcgtt atcttgatgt tttagatatt gccggtccgg cagcacgcaa agttaactga
    75601 cgccagagcc attccaccgg cccctggcgg aagtaacgca gccagataac agagaagagg
    75661 atattcgcca gccataccgg aataacaaac gccagcagct ccaggcggtc aaaatgcata
    75721 aacaaaccga ggtggtaaaa aagcgtggta caaatcagcg tttgcaatag atagttggtc
    75781 agcgccatcc gtccgacgca ggcgattgcc agcaccagct taaagcggct taattgcggc
    75841 cagaagccat aaaacagcga cgcatagcca atcgcctgaa acggcgcact cagttcccgc
    75901 ggcatttgaa gtaagaaggc acaccagcga tacgcccagt ccagctgcca ttgcagggcg
    75961 atggcaggaa ggttaatggt caccccaatc gccaccagca caaaaccagt acgacgatag
    76021 tgacgtaagc tgaactgccc tttcagccag ccgctgcgca tcagcgccgc accaatgagc
    76081 atcatcccag ccagttgcca gccatactgt gcgcccagtg ccagtaaact gttgccaaca
    76141 ccatcggcac gattactgat cgcatcaacg ccgccgtgaa gcttccagta tttttcatac
    76201 aaaatagccg atgcatccgg cgtccaggcg cggctggtct ggctgtcgga aatcagcccc
    76261 aataacagca aaacgccaag ccccaccaga taaagcatga cgccggtatt aaacaggctt
    76321 tttaccgatg gcgcatcgcg caccagccgc cagcagatta agcccaccag cccgtaagcc
    76381 agcagaatat cgccgtccca gaacaataaa ccgtgaataa agcccaataa gactaacagc
    76441 gttaaccgcg actggatcca gcgtctgcca cggggcagca acatttgcag tccagcacca
    76501 aacagcagcg caaaaagcgt gaggaatttc acctggccga tgagatcaag aaatgcccag
    76561 gtccatgcat cctgcggcgt aatagcaccg taccaggcgg gattgagata agccgccttt
    76621 ggtagcccaa aggcgctgat gtttaatagc aggatcccca gaatggcgac gccgcgaaca
    76681 aaatcgagcg tgacgttgcg ctccatggtt cctgcctttt aatcagttgt gatgacgcac
    76741 agcgcgcaga aactcgtggc gcgtattctg actggatttg aacaatccac caagagaggt
    76801 cgttgttgtg gcactggttg catcgcggat gccacgcgcc ttcacgcagt aatgcaccgc
    76861 gtcgatcgag acagccacgt tattggtgcc cagcagcgtt tgtagcgcaa taagaatttg
    76921 ctgcgtcaga cgttcctgca cctgcggacg ctgggcaaag aactgcacga tacggttaat
    76981 ttttgacaga ccgatcaccg aatctttcgg gatataagcc accgtcgctt tgccatcgat
    77041 ggtaacaaaa tggtgttcac aggtactggt cagagtgata tcgcgcacgg tgaccatttc
    77101 atcgaccttc attttgtttt caatgagggt gattttcggg aagttggcgt aatccagacc
    77161 ggagaaaatt tcatcgacat acattttagc gatgcgatgc ggcgtttcca tcaaactgtc
    77221 atcagccagg tcgagattca gcagctgcat gatttcggtc atatgaccag caataaggct
    77281 tttgcgcgtt tcgttatcca tttcatgcac gggcgggcgc agcggtgttt ccagtcctcg
    77341 cgcaactaac gcttcatgaa ccagggccgc ttctttactg agtgatggca tttatgattt
    77401 ctcctgcagg tgtgacgcct ccgccctgcg tgggggcaaa gttattaagc tgatttacag
    77461 cctgattatt gtgcgtgagg cggcgcacat aatccagtat tcacagcgat aattattgta
    77521 attgccgctg cctttcatca gcagatgtta aaacatcgtt atgcaaatac ggaagtgaaa
    77581 gttactcaca gcacattgaa taaacggtat gatgaagaaa ttgcaaacaa cacaacaagg
    77641 agccacgcat ggaaatgctc gaagagcacc gctgttttga aggctggcag caacgctggc
    77701 gacacgactc cagtacctta aactgcccga tgacgttcag tatctttctc ccaccccctc
    77761 gtgatcacac cccgccacca gtgctgtact ggctttccgg attaacctgc aatgacgaga
    77821 acttcaccac caaggcgggt gcccagcgcg tggcggcaga actggggatt gtactggtga
    77881 tgccagacac cagcccgcgc ggcgaaaagg ttgccaacga cgatggctac gatttaggcc
    77941 agggcgcagg cttttatctt aatgccacgc aaccgccgtg ggcgacgcat taccggatgt
    78001 atgattatct gcgcgatgaa ttaccggcgc tggttcagtc gcaatttaat gtcagcgacc
    78061 gctgcgccat tagcggtcac tcaatgggtg gtcacggtgc gctgattatg gcgctgaaaa
    78121 atccgggtaa atacaccagc gtttcggcct ttgcgccaat tgtgaatccg tgcagcgtcc
    78181 cgtggggaat caaagcgttt agccgctatt taggtgagga caaaaatgca tggctggaat
    78241 gggacagttg cgcgctgatg tatgccagta acgcgcagga tgcgatcccg acgcttatcg
    78301 atcagggcga taatgatcag tttcttgccg accagttgca acctgcggta ctggcagaag
    78361 ccgcgcgcca gaaagcgtgg ccgatgacgc tgcgtattca gccgggatat gatcacagtt
    78421 actacttcat cgcctctttt atagaggatc acctgcgctt ccatgcgcag tatttactga
    78481 agtgaaagtc cgcccggttc gccgggcatc ttctcatcag aagcgataat ccactgccat
    78541 aaagtaacga cgtccgtctt cgttatagct gtagtcgtca cgactgagat ccttgtcgcc
    78601 aaggttcagc acgcctgcgc gcagtttgac gtctttagtc acctgccagg ccgcgccggt
    78661 attccagatg gtataaccgc ccggtgtttt agccgtcgcg ctgtcggcgc gtttctgccc
    78721 ggtatagtga ccagaaacat agaatgacca gtcttccagc gccagcggtt tccagtccag
    78781 cgtaccgtta gcagtatgga acggcagatc ggatagcggt ttgttttcgc cgttgctgac
    78841 atcacgacca tcgttgtagg tgtagttgat cgacagtttc cattcatcgt tgaacggaat
    78901 tttcagttcg gtttccacgc cctgaatacg agctttgtta acgttgtagt agctaaatac
    78961 cggtatgcgc cgtccgttag cgcccgtctc aaaaccaaca aagttttggt agcccggtgc
    79021 agcgttgacg tcagacgtac ggctgatgct gatgcgatct ttcacatcgt tacggaaaac
    79081 ggtaacgctg gattcaaccc cttccagcca gccttcttca cccatgtagt aaagccccag
    79141 ctcccaactt tcgctggttt ctggtttcag atccgggcta cccacaatct tacatgcgcc
    79201 acggcaggaa ttgctcgtcc agtcagggct aagttgcaac agagaaggtg ctttaaatgc
    79261 cgtcgcccag ccccctttca ccgttacggt gtcggtggcg ttataaacca ggtaggcacg
    79321 cggactccag tgttcaccgt aggtttcgtg atcgtccata cgcacgccgg tcgtcagcgc
    79381 cagcggctcg aagatccgcc attcatcttc cacaaacagc gcgtactggc tggcagacgt
    79441 tttggagctg gttcccccgg tcaggttcac cgcatcgcta agtttgtcgt gacgccattc
    79501 accgccaacc gtgagaaact gattaatcgc cgtcagcggc aacgtgtatt tgccgtcgac
    79561 cgtattgctt tcggaagtta tcgggctgct gttgccaggg tttttgttct cgactttctc
    79621 accgtagtat ttcagttcgc tggtgccgta atcccaacgc ccattatggc tgacggagta
    79681 gttctggcgt tccaggcggt ttttgtccag cgagtcggaa tcacgatcct gacggtcgaa
    79741 accgtatccg gcagtaaaat cgtgattttg attcggtgtc caggcaaatt cgacattgcc
    79801 gtcgcggctg gagaatcctt caatacgcgg cgtttctccg gtatcggtgg tcgttgagtt
    79861 ttgcgggtca tccttttcac gttttgccag gctgccgtaa gctttcattc ccagcacacc
    79921 atcaattaat ggtccactgg taaagaactg accgttatag gtatcaccgc gatcgcgatg
    79981 ttcctgaatg gtggtatcga cggtaacggt acccgaccat ttctgaccga tttttttggt
    80041 gatgatattc actacaccgc cgagcgcatc ggagccgtat agcgacgaca tcgggccacg
    80101 aaccacttca atacgttcga tggaatcgac cgggatccag ttcagatcga aatcattgtg
    80161 gcggaagacg gcattgcggg agttaacgcg tttaccgtcg acgagaatca gggtgtagct
    80221 gctgtccaga ccacgaatac taacgccctt acggttatcc ccttcgttcg tcagttgtac
    80281 gccaggcact tctttgagga catccttcag attctgtacc ggttttcgct gcaggtcttc
    80341 ctgggtaatg acgctgatac tggcgggtgc atctttgagg ttttgttcaa cggaagatgc
    80401 agtgacaacc atcgtttcgc catcatcatc gaccgctaac acaggccatg cacaagaaat
    80461 agcggacaaa cacagcccga cccgtacgaa agggttcaac ctaaacattc catatctcca
    80521 tgaggtaact acgaaaataa aatgggttat cgctcacatc ttcttcacgt ccccttgcgt
    80581 acggcagcat cgcggtggac ttatttgtat gcaggtgatc atcccagaaa gccggaacag
    80641 cctctgattt gtcagccttt tttgattgcg gcgtaacgat aatgcaaacg ataacaatta
    80701 tcaatccaaa tgttaaattt tatatccgca tgatttgtca gggaaatgga attgaaaaag
    80761 ccctctcggt tgagagggct tagcaaggaa gggaggaaac ttatttctta tcgttctgcg
    80821 ggaacttcat ttcgctgtaa cgtacgaagt gagttccttt aatcagcttg tagccgaacc
    80881 aaataatcag gaacagcggg ataccaatat acgttgccgc tacgccgccc cagtcaatgg
    80941 tatctttcag gaacgcttcg tagttctggc ccaaagtgat aatcagacac agaatgaatg
    81001 cgaagatcgg ccccagtggg aagaaacctg aacggtacgg cagatcgtta atgtcgtgtc
    81061 cctgcaatac gtaaccgcga cggaagcgat agtggctaat ggcaatcccc agccaggcga
    81121 taaaacccgt catcccggag gtgttcagca gccacaggta taccgtctgg ttgccaaaca
    81181 tggaggtcag gaagcacaga ccggcaatca ccgtcgtcgc atacagcgca ttacgcggca
    81241 cgccaccacg cgacagttta gcgaaaatgt gcggcgcttt accgtcacac gccagggtgt
    81301 acagcatacg agtagacgca tacataccgg agttacccgc tgacagcacc gccgtcagaa
    81361 taactgcgtt catcaccgcc gccgcagaga gcagacccgc gtgctggaac accagggtga
    81421 acggactaac gctgatgtct ttaacatcgt tacgcagcag gctcggatcg gtgtacggaa
    81481 taatcaggct gataatcagg atcgcgaaca catagaacaa caggattcgc cagaacacct
    81541 gacgtaccgc gcgtggaatg tttttcgccg gatcttcgga ctcgcctgca gcaataccga
    81601 tcagctcggt tccctggaaa gagaagccga caatcatagc tacgccgatc atcgccgcaa
    81661 aaccaccagc aaacggcgct tcgccgattg tccagttgct ccagcccgca ggctgcgcgc
    81721 ctttgaagat accgataatc atcagcacgc caacgatgat aaagacaata actgtcgtga
    81781 ctttgatcag tgagaaccag tattccgctt caccaaagcc acgaactgag atgtagttca
    81841 gcaggaagat aacgccgagg aacaacgcac tccagatcca gcccggtgta tccgggaacc
    81901 accagctcat gaccagctga gctgcaacca ggtcaacggc gatagtcacc gcccagttgt
    81961 accagtagtt ccagcccagc gcgaagccaa agccttcttc aacatagttc tgaccgtaag
    82021 tggcaaacga accggaaacc ggcatatatg cagccagttc accgagactg gtcatcagga
    82081 agtaaaccat caggccaatc agcatatacg agagcaatgc cccgcccgga cctgcctgag
    82141 aaatcgttgc gccagaggca acaaaaagac ctgtaccgat ggaaccgcca atggcaatca
    82201 tcgtcaggtg acgcgccttt aattcacggc gtaagcccgg cgcttctgtg gttttagttt
    82261 cggaaaccat acaaaaatgc tatccatctt aaaaatgagg cgcgattgta gcagacgatt
    82321 ggcaatcctt ccggcagaaa tacacggtta taagacacct tcatgatcgc ccagggatta
    82381 taagtaaagc agccaatctc ttttctggcg aatgcatgct gagggcgctg cgtcacgaaa
    82441 tcgacacagc accagcatgt tcttgtacag caacttaacg cggtacattc gcgggatcgc
    82501 aatagtccag aaagcgccgt agcgcgttgg aaaggtgttt ttgccgatga tgtatacgcc
    82561 acaacgtacg catcaggcgc ggcagaggga ccgcaacttc acttaatgtg cctgcctgca
    82621 attgatcttc aatcacccgt cgcgacaggc aactaattcc caacccatga cgcaccgcat
    82681 gtttgattgc ctcggagtta cctaattcca tcgccatctc aaacttcggt aaatgtgaca
    82741 gcaatagata atcgacaatc tcccgcgtgc cggaaccgcg ttcacgcagg atccacggcg
    82801 cagcggccag ctgctctaag gtgaccggac cacgggccaa cggcgaagtc ggcgcggcga
    82861 aaaccaccag ctcgtcttcc agccacggtt cagaaataat ttcagtgctg tggcacggtc
    82921 cttcaataaa accaatatca acgcggaaat ccagcaccgc ttgcatcacg tcctggctgt
    82981 tcccaacgct aagttcaatc ggcaactgcg gataatcatg gcgataacgg gcgataactg
    83041 caggcagaat gtagttaccg atggtactac tggcatagat acgaatcgcg ccgttgtctt
    83101 cgcgaaacag ttgttcgatt tcaaccgcct gttcaagcaa tgccaacgca cgcggataga
    83161 gcagccgccc gtgttcatta acaaccagtc ttttccccac gcgatcaaac agttgcacgc
    83221 caagctgccc ttccaggtcg gtcaaggctg cgctcactgc tgattgcgac aacgccagca
    83281 tcaccgacgc ctgggtggtt gatccacttt tcaatacttc tgcaaaaact tccaactgcc
    83341 ggagggtgat gtgcatagtc gcttaccact tataaagatt aattataaat atataatcaa
    83401 ttttattttt aaaccagtta gtcgtaacct tatgcccggt taaaggagag ggttatgacg
    83461 aatatcacct tacagaaaca acatcgtaca ctgtggcatt ttattccggg gttagccctg
    83521 agtgcagtta tcaccggggt cgccctgtgg ggtggttcca ttcccgcggt tgcgggtgcc
    83581 gggtttagtg ccctcaccct cgcaatcttg ttggggatgg ttttaggcaa caccatctat
    83641 ccgcacatct ggaaaagctg tgacggtggt gtgctgtttg ccaagcaata tttattacgt
    83701 ctgggtatca ttctttatgg cttccgtctg acgttctcgc aaattgccga tgtcggtatc
    83761 agtgggatca tcattgacgt gctgacgctg tccagtacct tcctgctggc ttgcttcctg
    83821 gggcagaaag tgtttggtct ggataagcac accagctggt tgatcggtgc cggtagcagt
    83881 atctgtggtg ctgccgcggt actggcgact gagccggtag tgaaagcgga agccagtaaa
    83941 gtaaccgtgg ctgttgcaac cgttgttatc ttcgggaccg tcgcgatttt cctctacccg
    84001 gcgatatatc cgctgatgtc tcaatggttt agtccggaaa ctttcggtat ctacattggt
    84061 tctactgtgc acgaagtggc gcaggtggtg gcggcaggtc atgccatcag cccggatgcg
    84121 gaaaacgcag cagttatttc caaaatgctg cgcgtgatga tgctggctcc gttcctcatc
    84181 ctgctggcgg cgcgtgttaa acagctgtct ggggcgaaca gcggcgagaa aagcaaaatc
    84241 actattccgt ggtttgccat attgttcatc gtcgttgcca tctttaactc gttccacctg
    84301 ttaccgcaga gcgtggtgaa catgctggta acgctggata ccttcctgct ggcaatggcg
    84361 atggcggcgc tgggtctgac cactcacgtc agcgcgctga aaaaagccgg ggcgaaacct
    84421 ctgctgatgg cactggtact gtttgcctgg ctgattgttg gtggtggtgc gattaactat
    84481 gtgattcaaa gcgtcatcgc ataaaccact acatcttgct cctgttaacc cgctatcatt
    84541 accgttttcc tccagcgggt ttaacaggag tcctcgcatg aaatacattg gagcgcacgt
    84601 tagtgctgct ggcggtctgg caaatgccgc aattcgcgcc gccgaaatcg acgcaaccgc
    84661 gtttgccttg ttcaccaaaa accaacgtca gtggcgtgcc gcaccgctca cgacgcaaac
    84721 catcgatgaa ttcaaagcgg cctgtgaaaa atatcactac acatcggcgc aaattcttcc
    84781 ccacgacagc tatctgatta acctcggaca tccggtcact gaagctctgg aaaaatcgcg
    84841 cgatgccttt atagatgaaa tgcagcgttg cgaacaactg gggctttctt tgctcaactt
    84901 ccaccctggc agccatctga tgcagatttc agaagaggat tgccttgcgc gtattgccga
    84961 atccatcaac attgcgctgg ataaaactca aggtgtaaca gcggtgattg aaaacaccgc
    85021 cggtcagggc agtaacttag ggtttaaatt cgaacatctc gcggcgatta tcgacggcgt
    85081 ggaagataaa tcccgtgtcg gcgtctgcat tgatacctgc catgctttcg ctgccgggta
    85141 tgatttgcgt actccagccg aatgcgagaa aacgttcgcg gattttgccc gtattgttgg
    85201 ctttaagtat ctgcgcggga tgcaccttaa cgatgcgaaa agcacctttg gcagccgcgt
    85261 tgaccgccat catagcctcg gtgaaggcaa tatcggtcat gatgcgttcc gctggatcat
    85321 gcaggacgac cgtttcgacg gcattccgct gatccttgaa accatcaacc cggatatctg
    85381 ggcagaagag atcgcctggc tgaaagcgca acaaactgaa aaagcggtgg cctgatcgat
    85441 gaacgacagg gaaaagcaga ttcttaaaat tttacggcgt aacccgctga ttcaacagaa
    85501 tgaaatcgcc gatattctgc aaatcagccg ctcacgtgtt gccgctcata ttatggattt
    85561 gatgcgcaag ggtttgatta aaggcaaagg atatatcctt accgagcagg attactgtgt
    85621 ggttgtgggt gcaatcaata tggatattcg cggaatggcg gatatccgtt acccgcaagc
    85681 agcctctcat ccaggttctg ttcactgttc cgcaggcggc gtcggacgta atatcgcgca
    85741 taacctggct ctgcttggtc gggatgtgca tttaatatca gctattggca acgattttta
    85801 cggcgagaca ttactggaag aaacgcgccg cgcgggcgtg aacgtttcaa actgcattcg
    85861 tctgcatgga cacagcactg caacttatct cgctatcgct aataagcagg aagaaactat
    85921 cctggcaatc aatgacacac atattctgca acagctaacg cctcaactgc tcaatacttc
    85981 acgggacttg attcgccatg ctggtgtggt gctggctgat tgtaatctca cacctgaagc
    86041 cctggagtgg gtctttacca ttgctgatga aattccgatg tttgtcgata ccgtttccga
    86101 atttaaagcg aacaaagtaa aaaactggta cagccggatc cacactctga aaccaacaca
    86161 aaatgaactg gaaattttgt gggggcaacc gattaaagac gacaacgatc gcatcagagc
    86221 tgtaaattcg ctgcatcaac aaggtgttaa acgcattttt gtttatctga aagatgaatc
    86281 tgtattttgc agcgataagg atggagaaca atttttgctg accgcgccag cgcatacgac
    86341 agtagacagt tttggtgctg acgatggttt tatggcgggc ttggtatata gctttcttga
    86401 aggatacagt ttccgcgaca gcgcccgttt tgcggtagcc tgcgcggcaa tttcgcgcgc
    86461 cagcggcagc ttaaacaacc ctaccctgtc tgccgataac gcgctttcat tagtgccaat
    86521 ggtgtaacaa tgttgccgga ttcgacgctt gaccgcatct tatccggctc ataaattgcg
    86581 cactacgcta aaccaataaa gaatcctgca atagtagcac tcatcaggtt agaaagtgtc
    86641 gccgccgcca gcgcgcgtaa accaagttgg gcgatttccg gcgcacggtg tggcgcaacc
    86701 gcagaaaacg cccccaccac caccccgata gaaccaaagt tagcgaaacc gcacaacgcg
    86761 aaagaaataa tcgccacggt tttagcatcc agagtgccac ccgtttgcag atatggcgag
    86821 aaattgagat aagcgacaaa ttcattgatc gccagcttct gcccaatcaa actcccggca
    86881 agatttgcat cactccagtc aacccccatc acccacgcca atggggccaa caggtaacct
    86941 aaaatggact ccagcgaggc atgtgcaaaa ccaaaccagc cgccaacgcc gccgataata
    87001 ccattaatta acgcaatgat ggcgacaaat gccataacaa ctgtcgctac accggcggcg
    87061 attttcagcc cggtcattgc ccctgtcgca gcggcttcaa taatgctttt tggcggtgtt
    87121 tcggtgaaag agaggttatt aaaggaaacc tgcgaagatt ccgtagccgg gcttaacagg
    87181 cgggcaaaca agatcccgcc tgggatcgcc attaacgatg ccgccagcaa atattccaca
    87241 ggtacgccca gggcggcgta accaatcatt gtcgaaccag caatcgaggc catgccacta
    87301 caaatcgctg taaataattc attgcgattc agacgatcga taaagggttt gacgattgcc
    87361 ggaatttcgt tttgcccgag gaaaatggta gtgaccgcga cgaatgactc gatcttgctg
    87421 atatttaacg ctttctggaa gataccgccg agaatgcgaa ttaaaatccc catcacaccg
    87481 atgtagtaga gaatactcac cagtgctgta acgaagataa ttgccggtaa tactctgaaa
    87541 ccaaagataa atcctgcgcc atcaaacagc gtgtccattt tcggcccgac cagcgaaccg
    87601 aagataaatg cgctacccgc gtcgctgtac gccatcactt tatgcacgcc aaaagcgact
    87661 ttttcagcga cccaacgccc tggcggtaac caaagcataa tgccgccaat cacaacctgt
    87721 aacactaacg ccgcgccaac ggtacgcagg ctgatcttct tcttgtttac tgacagcaaa
    87781 aatgcaattg ccagcaatac caccattccc agaacacttc tcatgacatc catagtgatt
    87841 atctcttcat gtcatattgg gcgacggctt tctgcccatc agaaatagcc gggcctgcat
    87901 cttgcgctat cggcccggct tgttatcaac gcttaatggg ttttgatgta gccgcgcacg
    87961 cactcttcga ctaagcccca gaaccagtcg gtatcaatag tgatgccgac tttggtattg
    88021 gcgggcttgc caagaacgcc cagctcgtcg cagacggtgc gcccatagca agggccactg
    88081 ttgacgtcca cttcgacgta catctcctgg gttttaatgc catcagggtt aatcagataa
    88141 ccgatgcagg tggcgtcgtg caccgggccg ccagccaggc cgtagttttc gaactgcgtt
    88201 ttgagagtga agttcatgat gtcgctgaac agctctccgg cagggccgcc tgccctttcc
    88261 atccgagcaa tcacgtccgg ggtgcaaacg gtctggttgg tgagatcgag gcccatcatc
    88321 actaatggaa cgccagaggt gaacaccacg cgggctgctt ccgggtcagc aaagatgttg
    88381 aactcggcag atggcgtgaa gttgcctgta ccgtaagcgc cgcccattag cacaatttca
    88441 cggattttgg gcaggatcgc gggttgcata cgcattgcca ccgcgatatt tgaaagcgga
    88501 ccaaccggca ccagagtgat atcgccatcg cttgccatca gggtatcaat gatgtatttc
    88561 accgcgtggg tactttctgc ctggcgggtc agcggctcga ataccgggcc atccagtccg
    88621 gtttcaccgt gaatattatc ggcaacgatt tgttgacgca taatgggttg cggcatcccc
    88681 gcataaaccg gaacattaat ctccagtttc tggcaaacat tcaggccatt aattaatgtt
    88741 ttatcaagcg tctgattacc cgctacaata gtgatgccta ataaatctat tgccggatgt
    88801 ttcgccgcca tcattatagc aatagcatca tcatgacccg gatcacaatc cagaataatt
    88861 tttctctttt ccattgttta tttcctctgt ttccagttgc gttatttttt ctacagcaaa
    88921 gaaaatgcga ccgggccgat gattgaatct taccaaccgc gtacgtatgc taaatatgag
    88981 aaatctcata gcggataaac atcgtgaaag aaatccacaa taatgatctt aagcagcaat
    89041 tgatgagtga atccgcgttt aaggattgct ttttaacgga tgtttcagcc gatacgcggc
    89101 tgtttcattt tttagcgcgt gactacattg tgcaggaagg gcaacagccg tcctggctgt
    89161 tttacctgac gcgaggccgc gccaggcttt acgccacgct agctaatggt cgcgtgtcgc
    89221 tgatcgattt ctttgccgcc ccctgtttta ttggcgagat tgagttaatc gacaaagacc
    89281 atgaaccgcg tgcggtgcag gctattgaag agtgttggtg ccttgcgctc cctatgaaac
    89341 attaccgccc gcggttatta aacgacacgc tatttttacg aaaactctgc gtcaccttaa
    89401 gtcataaaaa ttatcgtaat attgtttctt taactcagaa tcaatcattt ccgttagtga
    89461 atcgcctggc agcatttata ttactctcgc aggaaggtga tctttatcac gaaaagcata
    89521 cgcaagcggc agagtattta ggcgtttctt atcgacatct tttatatgtt ctcgcgcaat
    89581 tcattcacga cggtttatta actaaaagca agaaagggta tctcattaaa aacagaaagc
    89641 agttgtcagg actggcgctg gagatggacc cggagaataa attctccggg atgatgcagt
    89701 aaaaattatt tgcaatagcg cgattgccgg atgcaacgct taatacgttt tatccggtct
    89761 acaaatcgag cattacgcca gaccaataaa gaacccggca atagtcgcac tcatcaggtt
    89821 ggaaagcgtt gctgctgcca gcgcccgtaa accaagctgg gcgatttctg gagcacgttt
    89881 tggcgaaata gccgaaaatg cgccaacgac aacaccgata gaaccaaagt ttgcaaaccc
    89941 acagagggcg aacgagataa tggcaatggt cttgacatcc agcgtgccgc tcgtttgcag
    90001 atagggcgag aaattgagat aagcaacaaa ctcattaatc gccagtttct gcccaatcaa
    90061 acttccggca agatttgcat cactccagtc cacccccata atccatgcca acggggccag
    90121 cacatagccg aaaatgcttt ccagagagac attggcaaaa ccaaaccagc cgccaactcc
    90181 accaataatg ccgttgatca gcgcaataat tgccacaaat gccattacca ccgtcgccac
    90241 accggcggcg attttcagcc cggtcattgc accgttcgcc gcagcttcaa taatgctttt
    90301 tggcggtgtt tcgctaaacg acagattttc aaacgtaact tgcgaaggtt ccgtcgccgg
    90361 actaagaata cgtgcaaaca ggataccgcc aggaatagcc atcagcgaag cggctaacaa
    90421 atagtcaatc ggcacgccca ttccggcata gccaatcatc atcgaacccg caatagacgc
    90481 catgccgcta caaatagccg taaatagctc gttgcgattc atgcgatcaa taaaaggttt
    90541 aacgatcgcc gggatctcat tttgcccgag gaaaatagtg gtgactgcga caaaagattc
    90601 gattttgctg atgttgaggg ctttctgaaa aatactgcca agaatacgaa tcagcagccc
    90661 cattacgcca atgtagtaca gcaagctgat aagcgcggta acgaaaataa tcgccgggag
    90721 tacgcgaaag gcgaagataa agcccgcacc gtcaaacaga acatccattt tgggaccgac
    90781 cagcgaacca aaaataaagg cacttcctgc gtcactgtag gacatcactt tatggacgcc
    90841 taatgccgcc tgctctactg cccattttcc cgggggaaaa tagagcatga tgccaccaat
    90901 ggcaatttgc agcagcagcg cagcgccaac cgtgcgcaag ctgatgctct ttttatttac
    90961 cgacaacaca aaggcaattg ccagcaatac caccatcccc acaacacttc tcattatatc
    91021 cataatgatt ttcccttcat gccagtaaac ccggcgtcag cgccaggttt tggtatgttt
    91081 gatgagtacg ggcgacggct ttctgcccgc cagaaattaa cccacgagac gctgatattc
    91141 tttggcaatt tcgctcgcca gaatggcgtt attaaagacc agttgaatat tggatttcag
    91201 gctatcaccg cctgttagct ccgcaacacg cgccagcagg aacggtgtac tctctttccc
    91261 aataacaccc tgttcttcgg cttcagcaac ggcttgatca attgctgcat tgatggtttc
    91321 ttctggcatc gcaaactgtt ccgggatcgg attcgccact accaggccgc cgttcaaacc
    91381 ggtttgccac ttcactgcca tcgcgcgagc aatttcgcgg gcactgtcaa gacgaatgct
    91441 gacttcaaat gggctggttc ggcagaaaaa cgcaggcagc gcttttgtct gataaccaat
    91501 taacggtaca ccgaaggttt ctaaatattc tgttgttaat cctaaatcga gaatagattt
    91561 tgcccccgca caaacaacag tgacattggt atttgccagt tcctgtaaat cggcagaaat
    91621 atcgaaggta tgttccgccc cgcgatgcac accaccaatt cccccggtgg caaatacttt
    91681 aattccggca agcgccgcaa taatcatcgt tgaagccaca gtggttgcgc cattttttcc
    91741 ggcggcaaca acaaaaggta aatcgcgacg actaactttg gtcacgttat gtccttcacg
    91801 gcccagcaat tcgatttctt ctttacttaa gcccactttc atcacaccgc caataatggc
    91861 gatagtggct ggtactgcgc cctgtttacg aatagtttct tctacttcaa ttgcggtttg
    91921 ggcattttgt gggaatggca ttccgtgaga aattatggtc gattccagcg caacaaccgg
    91981 ttttttgttt tttaaagcgt cctgcacttc cggggaaatt tgtaataatt caggggaaat
    92041 ttttaattca gacattctgc gttctccact aacgatataa cgttggcaat cgataaatcg
    92101 gggttattgg tgtattcaca ggagagcgcc attgacgaac atccctgtgc gaaacgaaca
    92161 gattcggcaa acggcattcc gtctacccaa cacgaagcaa gtcccgccat catggcatcg
    92221 cccgctccgg taacattaat aacattggtt ttgatcgggg cagaccagcc actttcaccg
    92281 ctgatatcac tgtaataaac gccatcgccg cccatgctca ataccagtcg gttcaggcca
    92341 tgttgatgga accaggcagc aacttttgcc acatctccac gccctgacag cgcaatccca
    92401 ctcagtgttt ccgcttcaag gcggtttggc ttcagagtgt ggatctgatt tagacggtcg
    92461 cgcactttga cacatttcca cgctgaaacc ggatcgacaa atacgggtac gttggcagca
    92521 ttatccagaa tccatgccag tgcctcttca ctgatattac agtccgcgac aatgaccttt
    92581 gccctctgaa taaattcacg gtgctgtgcg agatattcag ctgtaatagc gttgctaata
    92641 ttcatgtcat ttatagcaac cagcatttca ccggtattat cgagtaatga taaataactc
    92701 gacgtatttt ctcccggcac aatcaggcat ttatcgacat aaacgccaga ttgattggtt
    92761 tgcgttagca gcgattgacc ataaaaatca ctacctactg cgctcagtaa ccaggctttg
    92821 ttacccagca acgccaggtt ttgtgcaata tttcgcccta ctccaccagg tgtaaatttt
    92881 attttacctg gatttgaatc cgcataattt aatgattcat gtgaatatcc ggcgacatca
    92941 atattcgccg aacctataat tacgacataa tccttttcgc gcatagcacg tcctctggta
    93001 aaaaattacc aaccctgtca atccacaaga atatagatac tgcaaagaca gtttaaacat
    93061 gtgttcatat ttaaacatgt gctcatagta tgcatgtttt acgtaaagta aattgccgcc
    93121 agagaggcaa agcgggcaga tttgagcagg ctcacaaaat gcgattaaat gccagaatta
    93181 caaaagcgag gaatttgtga cgggatgcac agaacaggaa cactaaaaaa gggcagaaaa
    93241 gaatctgccc ttgaggaaat aaccttagtg tttgatgaac gtttcaggtt tctactgaaa
    93301 gataaaacca tttaaattca taaaattaca ttcacaaacc ggtcattctc tttgcgctca
    93361 tccaatgata cagggcagta aatttctgcc ctgtaacaca ccttttatta cgcggctttc
    93421 gctactgcgt ccacttccgg acgtttcagg aaggcatagg ccaaacccgc caccagcgta
    93481 ccggcaataa ttgctaccag gtaacccaat accggcgtaa tagcgccagg gatcagcaga
    93541 acaaacagac caccgtgcgg tgccatcagt ttcgcaccaa tcgccattga gattgcgcca
    93601 gtcagcgccc cacccacgat acagcacggc agcacacgca tcggatcacg agcagcaaac
    93661 ggaattgcac cttccgaaat aaagcacagt cccagtacca gagcggcttt gccaccttcc
    93721 tgctgcgctt tgtcgaattt gcgacgcgcc accattgttg ccaggcccat tgccagcggt
    93781 ggcaccatac ctgccgccat aatcgccgcc atcgggccat aggtttgagt actcagcaga
    93841 cccacaccga atgcgtacgc tgctttattt accggaccgc ccatgtcagt acacatcatg
    93901 ccaccgagga tcgcccccag cagaaccgca ttcgcagtcc ccatggtctg cagccagtga
    93961 gtcaaccctt cgagaatgcc agcaaccggt ttaccgatca ggtagatcat cgccagaccg
    94021 accaccagac tggaaattag cggaatgatc aggatcggtt tcagcgcctc catactctgt
    94081 ggcagtttca gttgcgtact gattaacttc gcaatgtaac cagccaggaa gcccgcaata
    94141 ataccgccaa tgaagccaga accggtgctg accgccagca taccgccaat cagacccggc
    94201 gtgagacccg gacgatcggc aatggagaag gcaatgtaac ctgccagtac cggcaccatc
    94261 agcgcaaagg ctgaaccacc accaatctgc atcagcgccg ctgccaacgt acccggctct
    94321 ttaaacgctt cgataccaaa agcaaaagaa agcgcgatac acagaccacc tgcaacgacc
    94381 atcggcagca tgtaagagac gcccgtcagc aagtgacggt atgcgcctgc actctctttc
    94441 ttaccttcag aggtcgccgt ttgagctttg cccgccggtt catacggcgt tgcttcagca
    94501 accgctttat ccagttcctg cgcggttttc ttcagcgcca gaccggtaga ggtacgatac
    94561 atcggtttac cagcaaattt cgccagatcc acttcgatat ctgccgccac aatcaccaga
    94621 tccgctgcgg ctacttcctc gggagtgatt gcattacccg cgccaacaga accacgggtt
    94681 tcaactttca cccaccagcc acgttttttc gcttcggttt caatggcttc agccgccata
    94741 aaggtgtgtg ctacgccagt cgggcaagca gtcaccgcaa ctacgcgttt cggaccgctg
    94801 gcggcaaccg gtgctgtcgc agtgaccggc gcagtgtaag gtttcgcatg gcctttggct
    94861 tcactcagga acagctcagg gtgcgcaact gcccgggaaa tatcacccag ccagacattt
    94921 ttaccgttca gcgcgctgtc attcgggatg gaatcaccga gaacaatcgc catttctgcg
    94981 tcgttcggat tgtcgatgat ttccagtttt gcttttcgcg ccgccgcgcc cagcagggtc
    95041 ttcgccatat aggcgcgtgc ctgaccgaga ttagcgtcaa taatcagcag cgttttcatt
    95101 atgcctctcc tgctgtcagt taaaaggttg taagtcgacg cgcgccatca ttgcggccaa
    95161 ctgcggacga tcggtaatac ccacattgct ttgacttacc gccagggctg caacagcagt
    95221 cgccagacgc agtgtgtgtt cactggattc acgcatcagc aagccataaa tcaggccacc
    95281 aaccatagaa tcccctgcgc caacggtgct tacgacatcg actgacggtg gtttggcgat
    95341 ccattcgccg gaggcattaa cccaaagcgc gccttcggca cccagtgaaa taacaacatg
    95401 cgcaatacct tgttcacgta gcgcatgtgc agcttcaatc acatctttca tttcaggcag
    95461 tttacggcct gcccagattt ccagctcgcg gcggttaggt ttcaccagcc acggtgccgc
    95521 tttcaaacct gctactaacg cttcacggct actatcaaag ataatgcaag gacactgact
    95581 acgcaggcga gtcatccagt cggtgaacgc ttccgggctg acgcctgacg gtaagcttcc
    95641 gctgacacag accatatcga actgaccgag ccagctcaga gaatcagtca caaagcgttc
    95701 ccagtcggcg ggggtgactt caaaacccga gaagttgaag tcggtcactt cgccgtcttt
    95761 ttccgtcagc ttaacgttaa ttcgggtgcg cccctgtaca acctggaaac ggttggcaat
    95821 gcccagctcg ctgaacagtt gctgaaaacc atcctgattg tctttaccga ggaagccgcc
    95881 aacggtgaca tcaattccca ggtcttttaa tactttggcc acgttgatgc ctttacccgc
    95941 cgcatgcaga ccggtggttt tcaccaggtt cacttcgccg cgttcaattt ccgggcagaa
    96001 accaacaagg tcataagccg gattaagggt gatagtagca acacgtctgc tcattatgcg
    96061 ccctccccaa gaccagcagc gatagcgtcg ccgattgctt tcagcgcctg ttcagcatct
    96121 gcaccctggg cggtaaagcg taggcgatga cctttcttaa cgccaagtgc cacaactttc
    96181 atcagactac gtccgtttgc cggtttgccg gtgccatcaa ggtttgtcac ggtaatatca
    96241 ctgttaaatt gtttaatggt attgaccagc atggtacctg gacgagcatg caggccgtgt
    96301 tcattgcgca ccacaaactc cgcgcttaac acgtcgtcgg tcggcgcatc atcgctggtc
    96361 agcagcgcca gcaacgttgc cgcatccgct ttcagcaagc ggtcagcttt attgtcgagc
    96421 aacaaatcag cgagacgctt aagaaccgca atgggctgat cgtcattcat cgccacactc
    96481 accagcatgg ctgccgtttc gccgtccaca tcaaaagcat ttgccgcacg gcttaccgca
    96541 atcgcgctac gcagattgcc ttcggcgcta tcgctcagcc agataccctg tccgaggttc
    96601 agcggttgtt cattgatggc tttggtgacg aaagtggcgt caactgccct cgcctctttc
    96661 agacgcgcag cgttcagcgc ctgaagagtc agcagatcgc tggcgacgat atccagcgtc
    96721 agcatttcgt tgtcgagctt cagctgctca ctctgctttt cgcccatcag taatgcgcga
    96781 agttcttctg ctgttggtgc tgacttcagt tgttcagcaa cggaatcatc gctcagtacg
    96841 tgggtcagct ggcgtagcag gcccagatgt tcatccgagc tggcagcaat accgattgcc
    96901 acgtacgcta cctgaccgtc accccaggtg acgccttccg ggaactgaaa tacctgaacg
    96961 ccggttttca gcacctgatc gcgggtgtcg gtagtgccgt gtggaatagc aataccattg
    97021 ccgaggaacg ttgaggtttg ctgttcgcgc gccagcatgc cattgacgta gccttctgct
    97081 acattaccgg cctgcaccag cgccgcagcg acctggcgaa tcgcctcttc tttgtctccg
    97141 gccttttcgc ccggatggat gtcctgtacg gataactgga acatagttct cctctcttgc
    97201 tgaattgaaa cgattcagcc tctatgagaa aaaaagcgcc aacctggctt agggttaaag
    97261 acaagatcgc gctgaaacgt ttcaagaaag cataatactt ctgtttcagc acgcaaggaa
    97321 agccgtaaag ttatgagcaa aagtttgatg tgctgcacaa ttttttgcca tttttcctaa
    97381 ttgctgatgg gaaaatccgt tatcagcaat ttcatttcag cagcgtcagc agccaatcag
    97441 caacagtgaa atggcatttt gattattcgt ggcgcttttg atttcgctgt ctgtttattt
    97501 tctgacaagc agcgtaaact ccgcgtcttc ctcttccagt gatcgaccag catgcataac
    97561 tcccccgcag tctccagcgc gaaatcgttt gacctgacct cgacggcgtt tttaatcgtt
    97621 gcctttctca ccggtattgc gggcgctctg caaaccccga cactcagtat ttttcttact
    97681 gatgaagtac atgctcgtcc ggcgatggtg ggattcttct tttccggcag cgctgtcatt
    97741 gggattctgg taagtcagtt tctcgccggg cgctctgata agcgcggcga tcgcaaatcg
    97801 ctgattgtct tttgctgcct gttaggcgtg ctggcctgca ccctttttgc ctggaatcgc
    97861 aactactttg ttttgctatt cgttggcgtc tttcttagca gctttggctc gaccgctaac
    97921 ccgcaaatgt ttgcccttgc ccgtgaacat gccgacaaaa ccggacgtga ggcggtgatg
    97981 ttcagctctt ttttacgcgc tcaggtttca ctggcatggg tcattggccc accgctggct
    98041 tatgccttag cgatgggttt cagctttacg gtaatgtatc tgagcgcagc ggtagcgttt
    98101 attgtttgcg gtgtgatggt gtggctgttt ttaccgtcga tgcaaaaaga gcttccgctg
    98161 gcgaccggca cgatcgaagc gccgcgccgt aaccgtcgcg atacgctgct gctgtttgtc
    98221 atttgtacat tgatgtgggg ctcgaacagc ctgtacatca tcaacatgcc gctatttatt
    98281 atcaacgaac tgcatcttcc cgagaaactg gccggtgtga tggggaccgc cgccgggctg
    98341 gaaatcccga cgatgttgat tgccggatat ttcgccaaac gtctgggtaa gcgtttctta
    98401 atgcgcgttg ctgccgtggg tggcgtctgt ttttacgcag gaatgctgat ggcgcattca
    98461 cctgtcattc tgttgggctt gcagctgcta aatgctattt ttattggcat tctgggcggc
    98521 atcgggatgc tctattttca ggatctgatg cccggtcagg cgggttcagc caccacgctc
    98581 tataccaaca cgtcgcgcgt gggctggatc atcgcaggat cagtggcggg catcgtcgcc
    98641 gagatctgga attatcacgc tgtgttctgg tttgcgatgg tgatgattat cgccactctg
    98701 ttttgcttac tgcggattaa agatgtttaa ggcgcggtca gcatttccag atcgataagc
    98761 caggtcatgg cctgctgacg cgagttaccg cacatttcag cgctggcttg taagcctgca
    98821 cagactttcg gtcgcagtgg cgaggtgaat attttacagc gttgctgttc atcaagctga
    98881 atgcagggcg tattggcggg cttgccatct ggcataccgg gaatagggct ggaaattgaa
    98941 ggggcagtgc aacacgcccc gcaacccgga cggcatttca tacgttgttc tcttaaggtt
    99001 aaccaccgga ttgatgagcg cgcacagtac cacctttttt gcaccagcaa aagtgcgaat
    99061 accacttgcc cgaaaggccc gtcgcgagta ctttgtcgcg atatttttga cattttcgac
    99121 tacaggaatt tttcgatgcc aagagcgaac gaaattaaaa aaggtatggt actgaattac
    99181 aacggcaaac tgctgctggt taaggatatt gatattcagt cgcccactgc ccgcggtgcc
    99241 gctacgctgt acaaaatgcg tttttctgat gtccgtaccg ggctgaaagt agaagagcgt
    99301 ttcaaaggtg atgatatcgt tgacaccgtg acgctgaccc gccgttacgt tgacttctcc
    99361 tatgtcgatg gcaacgaata tgtctttatg gataaagaag actatacccc gtataccttc
    99421 accaaagatc agattgaaga agagttgctg tttatgccag agggcggcat gccggacatg
    99481 caggtgctga cctgggacgg tcaactgctg gcgcttgagc tgccgcagac cgttgatctg
    99541 gaaatcgttg aaaccgcacc aggcatcaaa ggggcatctg ccagcgcccg taacaaaccg
    99601 gcgacattga gcactggtct ggtgattcag gtaccagaat acttaagccc gggcgaaaaa
    99661 attcgtatcc atatcgaaga acgccgttat atggggcgtg ctgactaact tcagccgcat
    99721 gcagaaaagg gatagctcag gctgtccctt ttttaattta ttataccaat cttctatttt
    99781 gcgcttcctg aacaccttac gccctcaatt ttcactcgtt gattgatcgc cctcacactt
    99841 catcgcatta acaatccaga ccaatttcaa ttgctgtcat ataactttac actgtcattg
    99901 ttaatttatc gttactaaga cgtgactcct atgaagacaa ttgcctccgt tacgctcccg
    99961 catcatatac acgctccacg ctacgatcgc cagcagttgc aatcacgtat cgttcatttt
   100021 ggctttggcg cctttcaccg cgctcatcag gcgttactga ccgatcgtgt gctgaatgcc
   100081 cagggcggcg actgggggat ctgtgaaatc agcttgttca gcggtgatca actgatgagc
   100141 cagctccgcg cacagaacca tttatatacc gtgctggaaa aaggtgcgga cggcaatcag
   100201 gtgataattg tcggtgccgt tcacgaatgc cttaatgcaa aactggattc cttagcggca
   100261 attattgaga aattttgcga gccacaggtg gcaattgttt ccctgacgat taccgaaaaa
   100321 ggctattgta ttgacccggc caccggtgca ctcgacacca gtaatccgcg gattattcac
   100381 gatctacaaa cccctgaaga acctcactcc gcaccgggta ttctcgtcga agcactgaaa
   100441 cgccgccgtg agcgaggcct tacaccgttt accgtgctct cctgcgacaa tattcccgac
   100501 aatggccatg tggtgaaaaa cgcggtgctg ggaatggcag aaaaacgttc gccagaactc
   100561 gccgggtgga taaaataaca cgtcagtttt ccgggaacca tggtcgaccg cattgttccg
   100621 gctgcaaccg acgaatcact ggcagaaatc agccagcatc tgggggtaaa tgatccctgc
   100681 gcgattagct gcgaaccgtt tatccagtgg gtggtggaag ataacttcgt cgctgggcgt
   100741 cctgcctggg aagtcgcagg tgtacaaatg gtgaatgatg tcctgccatg ggaagagatg
   100801 aaactgcgta tgcttaatgg cagccactct tttctcgctt atctgggtta cctttcagga
   100861 ttcgcccata tcagtgattg catgcaggat cgcgcatttc gccatgccgc cagaacatta
   100921 atgctgaatg agcaagcgcc gacactacaa attaaagatg tcgatttaac acaatatgcg
   100981 gacaagttaa ttgcacgttt tgctaatccg gcgctgaaac ataagacctg gcaaatcgca
   101041 atggatggta gccagaaatt accgcaacgt atgctggcag gtattcgcat acatctgggg
   101101 tgcgaaacgg actggtcgtt gctggcatta ggcgttgctg gctggatgcg ttacgtcagc
   101161 ggcgttgatg atgccggaaa tgccattgat gttcgcgatc cgcttagcga taaaattcgc
   101221 gaacttgttg cgggcagcag cagtgaacaa cgcgtaaccg ccctgctttc cctgcgtgaa
   101281 gttttcggtg atgatctgcc agataacccg cattttgtgc aggccatcga acaagcctgg
   101341 caacaaatcg tacaattcgg cgcacatcag gcgctattaa acaccctcaa aatttaacga
   101401 tttctgcggt taaagcggat gaagctcacc ttcgtccgct ctccccttct cttttctgcc
   101461 ttttttagcc aggattaacg ctcagttaac ttaccagagt attgcggagc cgttgtgacc
   101521 aggaccaacc tcatcaccgg ttttctcggc agcgggaaaa ccacgtcgat tcttcatctg
   101581 ttagcccata aagatcccaa cgaaaaatgg gcggtactgg ttaatgaatt tggggaagtc
   101641 ggaattgatg gtgctttgct cgccgatagc ggcgcattgc tgaaagagat ccccggcggc
   101701 tgcatgtgct gcgttaatgg tttacccatg caggtagggt tgaatacctt actgcgtcag
   101761 ggaaaaccag accgcttgtt gatagagccg accgggctgg gccatccgaa acagatcctc
   101821 gatctgttaa ccgcaccagt ctatgaaccg tggatagatc tgcgcgccac cttgtgcatt
   101881 ctcgatccgc gcttgctgct ggacgaaaaa agcgccagca atgaaaactt ccgtgaccag
   101941 ctggctgccg cagacatcat tgtcgccaat aaatccgacc gtgcgacgcc cgaaagtgag
   102001 caagcgctac agcgttggtg gcagcaaaat ggtggcgatc gacaattaat tcacagtgag
   102061 catgggaaag ttgacggtca tcttctggat ttgccgcgtc gcaatttagc cgagttgccc
   102121 gccagcgccg cgcattctca tcagcatgtc gtgaaaaaag ggttagcagc gttaagcctg
   102181 ccagagcatc aacgctggcg tcgcagtctg aacagcgggc aaggatatca ggcctgcggc
   102241 tggatattcg acgctgatac ggtattcgac accattggca ttctggaatg ggcgcgactt
   102301 gcaccggtgg aacgcgtcaa aggcgtgctg cgtattcccg aagggctggt acgaatcaac
   102361 cgtcagggcg atgacctgca cattgaaacg caaaacgttg cgccaccgga cagccgtatt
   102421 gagctgattt ccagcagcga agctgactgg aatgctttgc agagcgcgct gttgaagctt
   102481 cgtttagcga ctaccgcgta aggttgcctg cgtttttcag taagataatt agagaaaata
   102541 tgattaaaaa tttgccgcaa atagtgttgt tgaatattgt cggcctcgcg ctgtttcttt
   102601 cctggtatat tcccgttaat catggattct ggttgccgat tgatgcggat attttttatt
   102661 tctttaatca gaaactggtc gaaagtaagg cctttttgtg gctggttgca ttgaccaaca
   102721 atcgcgcttt cgacggttgt tctctgctgg cgatgggaat gttgatgctg agtttctggc
   102781 tgaaagaaaa cgcccctggc agacgacgta tcgtgattat gggtctggtc atgctattaa
   102841 ctgcagtgct attaaaccag ctgggtcagg cattaattcc tgtaaaacgg gccagcccaa
   102901 cattgacttt taccgatatt aaccgcgtca gcgaactgct ctctgttccc acgaaagatg
   102961 cctcacgaga tagctttccc ggcgatcacg gcatgatgct gcttattttt tcggcattca
   103021 tgtggcgtta tttcggcaaa gttgcaggcc ttatcgccct tattattttt gtggtttttg
   103081 catttcccag agtaatgatt ggcgcacact ggtttactga catcattgtc ggttcgatga
   103141 ccgtgatatt gatcggtttg ccctgggtgt tgctgacgcc attaagtgat cgattaatca
   103201 ccttttttga caaatcacta ccgggaaaaa acaaacattt ccaaaacaaa taactcacag
   103261 taattaacat catcaggctt atttttatag tgaggataat cctgatgatg cgcaccgtgc
   103321 tttcatccat cgcgcgcaaa aatcattctc taagtaaatg aatggattgc atgcgtttca
   103381 ctcaatcgta ctttaattga ccaatcccgc ttattaactt tctgtatcac tttttcttat
   103441 aaaaaatcat gtaaaaccgc tcgccaagac cgcaccaatc gggtaatctc gaactcgttt
   103501 tgcctcggcg gtagattatc ctcacagcat ataattttgt gcgttagtcc acagatttgg
   103561 ccttaaggaa ttgtttcaac atgcccaggt aattagtctc gtgtcgcttg gcattttttt
   103621 ataacgatat ttgtcgttaa ggacttcaag ggaaaacaaa caacatggtc aaatctcaac
   103681 cgattttgag atatatcttg cgcgggatcc ccgcgattgc agtagcggtt ctgctttctg
   103741 catgtagtgc aaataacacc gcaaagaata tgcatcctga gacacgtgca gtgggtagtg
   103801 aaacatcatc actgcaagct tctcaggatg aatttgaaaa cctggttcgt aatgtcgacg
   103861 taaaatcgcg aattatggat cagtatgctg actggaaagg cgtacgttat cgtctgggcg
   103921 gcagcactaa aaaaggtatc gattgttctg gtttcgtaca gcgtacattc cgtgagcaat
   103981 ttggcttaga acttccgcgt tcgacttacg aacagcagga aatgggtaaa tctgtttccc
   104041 gcagtaattt gcgtacgggt gatttagttc tgttccgtgc cggttcaacg ggacgccatg
   104101 tcggtattta tatcggcaac aatcagtttg tccatgcttc caccagcagt ggtgttatta
   104161 tttccagcat gaatgaaccg tactggaaga agcgttacaa cgaagcacgc cgggttctca
   104221 gccgcagcta ataaaccgtt tggatgcaat cccttggcta tcctaacgag ttaactgaaa
   104281 gcactgctta ggcagtgctt ttttgttttc attcatcaga gaaaatgatg tttccgcgtc
   104341 ttgatccagg ctatagtccg gtcattgtta tcttttaaat gttgtcgtaa tttcaggaaa
   104401 ttaacggaat catgttcata cgcgctccca attctggacg taagctcctg cttacctgca
   104461 ttgttgcagg cgtgatgatt gcgatactgg tgagttgcct tcagttttta gtggcctggc
   104521 ataagcacga agtcaaatac gacacactga ttaccgacgt acaaaagtat ctcgatacct
   104581 attttgccga cctgaaatcc actactgacc ggctccagcc gctgacctta gatacctgcc
   104641 agcaggctaa ccccgaactg accgcccgcg cggcgtttag catgaatgtc cgtacgtttg
   104701 tgctggtgaa agataaaaaa acattctgtt catctgcgac cggtgagatg gacattccac
   104761 tcaatgaatt gattccggcg ctcgacatta ataaaaatgt cgatatggcg atcttacccg
   104821 gcacgccgat ggtgccgaac aaacccgcaa tcgtcatctg gtatcgcaac cctttgctga
   104881 aaaatagcgg cgtctttgcc gctctgaatc tcaacctgac gccttcactc ttttatagtt
   104941 cacggcagga agattacgat ggcgtcgccc tcattattgg caatactgcg ctatctacct
   105001 tttcttcacg tttgatgaac gttaacgaat taaccgacat gccagtccgt gaaactaaaa
   105061 ttgcgggcat tcctctgacc gttcggcttt atgcagatga ctggacatgg aacgatgtgt
   105121 ggtacgcatt tttactgggc ggcatgagtg gaactgtcgt tggcctgctc tgctattacc
   105181 tgatgagcgt acgtatgcgc cccggcagag aaatcatgac cgccatcaag cgcgaacaat
   105241 tttacgtggc gtatcaaccg gtggtggata cacaagcttt gcgagtaacg ggcctggaag
   105301 tactgctacg ctggcggcat cctgtcgcgg gagaaattcc cccggatgcc ttcattaact
   105361 ttgccgaatc gcaaaagatg attgtgccgc tgactcagca tctgtttgag ttaattgccc
   105421 gcgatgccgc agaattagaa aaagtgctgc cggtaggcgt caaatttggc attaacattg
   105481 cgccggacca tctgcacagc gaaagcttta aagcagatat ccagaaactg ctcacttccc
   105541 tacccgcaca ccatttccag attgtgctgg aaattaccga gcgcgatatg ctgaaagagc
   105601 aagaagccac acaactcttc gcctggctgc actcggtagg cgtagaaatt gctattgatg
   105661 acttcggcac cgggcacagc gcgcttatct atcttgagcg ttttacgctc gattatctga
   105721 aaattgaccg tggatttatc aacgccatcg gtacggaaac gatcacttca cccgtacttg
   105781 acgcggtgct gacgctggcg aaacgcctca atatgctgac ggttgctgaa ggggtcgaaa
   105841 cgccggaaca agcgcgatgg ctaagcgaac gcggcgttaa tttcatgcaa ggctactgga
   105901 ttagtcgccc gttaccgctg gacgattttg ttcgctggct gaagaaaccg tatacgccgc
   105961 agtggtaagg tgtgcttacg tcccttatta ttcatagtga aagcatgccg gattgcggct
   106021 aatgatgagt aaaaggaaat ccgttgcaga tgattgtgcg catactgctg ctgtttatcg
   106081 ctctgttcac ctttggtgcg caggcgcagg ctatcaagga aagctatgcc tttgccgtgc
   106141 tgggcgaacc ccggtacgcg tttaatttca accattttga ttatgtgaac cccgccgcgc
   106201 caaaaggtgg gcagataacg ttgtcagccc tcggtacctt cgataatttc aaccgctatg
   106261 cactgcgcgg caacccgggc gcacgcaccg agcagctgta cgacacgcta tttacgactt
   106321 ccgatgacga accaggcagt tattacccgc tgattgctga aagcgcacgc tatgctgacg
   106381 attattcctg ggtggaggtc gctattaatc cgcgcgcccg ttttcatgat ggttcgccca
   106441 ttactgcccg cgatgtagag tttacttttc aaaaatttat gaccgaaggc gtgccgcaat
   106501 ttcgtctggt ctacaaaggc accaccgtca aagccattgc gccgttaacc gtgcgcattg
   106561 agttagctaa acccggcaaa gaagatatgt tgagtctgtt ttcgctgccg gtatttccag
   106621 aaaagtactg gaaggatcac aaacttagcg atccgctcgc cacgcctccg cttgccagtg
   106681 gtccgtaccg aattacgtcc tggaaaatgg ggcaaaatat tgtctattcc cgcgtgaaag
   106741 attactgggc agcaaactta ccggtaaacc gtggacgctg gaatttcgac accattcgct
   106801 acgattatta cctcgatgat aatgtcgcct ttgaagcgtt taaagcaggt gcctttgatt
   106861 tgcgtatgga aaacgacgct aaaaactggg ccacgcgtta taccggtaaa aatttcgata
   106921 aaaaatacat catcaaagat gagcaaaaga acgaatcagc ccaggatacg cgctggctgg
   106981 cgtttaatat ccaacgtccg gtattcagcg atcgccgggt ccgggaagca atcaccctcg
   107041 cctttgactt tgaatggatg aacaaggcgt tgttttacaa tgcctggagt cgcacgaaca
   107101 gttattttca gaataccgaa tacgcggcca gaaattaccc cgacgccgcg gagctggtgc
   107161 ttctggcacc aatgaaaaaa gatctaccgt cagaagtctt cacacaaatc taccagccgc
   107221 cggtatctaa aggcgatggc tacgatcgtg acaacctgtt aaaagccgac aaacttctca
   107281 acgaagcggg ctgggtgctg aagggtcagc aacgcgttaa tgccacaacg ggtcagccac
   107341 tcagctttga attattgctt cccgcaagca gcaatagtca gtgggtattg ccgttccagc
   107401 acagcctgca acggctgggt atcaacatgg acattcgcaa ggtggataac tcgcaaatca
   107461 ccaaccgcat gcgcagtcgc gactatgaca tgatgccgcg cgtatggcgg gcgatgccgt
   107521 ggcccagttc cgatttacag atttcctggt catcggaata tatcaattcc acttataatg
   107581 cccccggcgt gcaaagtccg gttatcgact cgctgatcaa tcaaattatt gccgcgcagg
   107641 gaaataaaga aaaattactg ccgttagggc gagcactgga tcgcgtatta acgtggaatt
   107701 attacatgct gccaatgtgg tacatggcgg aagaccgtct cgcctggtgg gataaattct
   107761 cccaacccgc tgtacgccct gtttacagcc tgggtatcga tacctggtgg tatgacgtta
   107821 ataaagcggc caaactgccg tcagccagac aacagggaga gtagatgggc gcttatctga
   107881 ttcgccgtct gttgctggtg atcccaacgt tatgggcgat tatcactatc aactttttca
   107941 tcgtgcaaat tgcgcctggc ggtccggtcg accaggccat cgccgccatt gagtttggta
   108001 atgccggagt attacccggc gcaggcggtg aaggtattcg cgccagccat gcgcaaacgg
   108061 gcgtcggcaa tatcagcgac agtaattacc gtggcggacg cggattagat ccagaagtga
   108121 tcgccgagat cactcatcgc tacggtttcg ataagccgat ccacgaacgt tacttcaaaa
   108181 tgatctggga ctacatccgc tttgattttg gtgatagcct ttttcgcagc gcctcggtgc
   108241 tgacgctgat taaagacagt ctgccggttt ccatcaccct cggattgtgg agcacgctga
   108301 ttatctatct ggtgtcgatt ccgttaggca ttcgcaaagc tgtttataat gggagccgct
   108361 ttgacgtctg gagtagcgca tttatcatca tcggctacgc cattccggcc tttttgtttg
   108421 ccatcctgct gattgtcttc ttcgcgggcg gcagctattt cgacctgttc cctctacgcg
   108481 gcctggtttc cgctaacttt gattcgctgc cgtggtatca gaaaatcacc gattatctgt
   108541 ggcatatcac gctgccggtg ctggcgacag tgattggtgg ctttgcggcg ctgaccatgc
   108601 tgaccaaaaa ctcattcctt gatgaagtgc gcaagcaata cgtggtgacc gcgcgtgcga
   108661 aaggggtaag tgaaaaaaat attctctgga aacatgtgtt ccgcaacgcc atgctgctgg
   108721 tgattgccgg ttttccggcg acgtttatca gcatgttttt taccggctcg ctgctgattg
   108781 aagtgatgtt ttcactcaat ggccttggct tactgggcta cgaagcgacc gtctcgcgcg
   108841 attatcctgt aatgtttggt accttgtata ttttcaccct gattggcctg ctgctgaata
   108901 ttgtcagtga tatcagctat acgctggtcg atccgcgtat agattttgag ggacgttaat
   108961 gtcgcgactc agccccgtca atcaggcccg ttgggcgcgt tttcgccata accgtcgcgg
   109021 ctactggtcg ttatggattt tcctcgtttt gtttggtttg agtttgtgtt ctgaacttat
   109081 cgccaacgat aaaccgttgc tggtacgtta tgacggcagt tggtatttcc cgttgttgaa
   109141 aaactacagc gaaagcgatt ttggcggccc gctggcaagt caggctgatt atcaggaccc
   109201 gtggctgaaa caacggctgg aaaataacgg ctgggtactg tgggcaccga ttcgctttgg
   109261 tgctaccagt atcaactttg ctaccgataa gcccttccct tctcccccct cccggcaaaa
   109321 ctggctggga acggatgcca acggcggcga tgtgctggca cgcattctct atggcacgcg
   109381 gatctcggtt ctgtttggcc tgatgctgac tctctgttcc agcgtgatgg gcgtgctggc
   109441 gggggcgcta caaggctatt acggcggtaa agtcgatctc tggggacaac gctttattga
   109501 agtatggtcg gggatgccga cgctgttttt gattatttta ctttccagcg tcgtacagcc
   109561 taacttctgg tggctgctgg caattactgt cttgtttggc tggatgagtc tggtcggcgt
   109621 ggtgcgggcg gagtttttac gtactcgtaa tttcgactac attcgtgcgg cacaggcgct
   109681 tggcgtcagc gatcgcagta tcatcctgcg tcatatgttg cctaatgcca tggtcgcgac
   109741 cctcaccttt ttaccgttta ttttatgtag ttcgataacc accctgacct cgctcgattt
   109801 cctcggcttc ggtctaccgc tcggttcacc gtcactcggt gaactgctgt tacaagggaa
   109861 aaataacctt caggccccgt ggcttgggat caccgccttc ttgtcggtgg cgatattatt
   109921 gtctttgctg atctttattg gtgaagccgt ccgcgacgca tttgatccta ataaggcggt
   109981 gtagcatgac gcaaactctg ttagcgattg aaaatttgtc ggtgggtttt cgccatcagc
   110041 aaaccgtacg tacagtagtc aatgatgttt cactacagat tgaggctggc gaaacgctgg
   110101 cgctggtggg tgagtcaggt tcaggcaaaa gcgttaccgc gctgtcaatt ttacgcctgc
   110161 tcccttcccc gccggttgaa tatctctccg gcgatattcg ttttcatggc gaatcgctgc
   110221 ttcatgtcag cgatcaaacg ttgcgcggtg tacgcggtaa taagatcgcc atgatttttc
   110281 aggaaccgat ggtgtcgtta aatccattgc ataccctgga aaaacagctt tatgaagtgc
   110341 tttcactcca ccgcgggatg cgtcgggaag cggctcgtgg cgaaattctt aactgccttg
   110401 atcgcgttgg tatccgccag gcggcaaaac ggctgacaga ttatccgcat cagctctccg
   110461 gcggcgaacg ccagcgggtg atgattgcga tggcgctgtt aacgcgaccg gaattattaa
   110521 ttgccgatga accgaccacc gcactggacg tctctgtcca ggcgcagatt ttacagctgt
   110581 tgcgcgaact gcaaggcgag ctgaatatgg gcatgctgtt tattactcat aacctcagca
   110641 ttgtcagaaa actggcccac cgcgtggcgg taatgcaaaa cggtcgctgt gtcgagcaaa
   110701 attacgccgc tacgctattt gcatcaccca ctcatcctta cacacaaaag ctactcaaca
   110761 gtgaaccgtc aggcgatcca gtgccgttgc cagaacctgc ctcaacgttg ctggatgttg
   110821 aacagcttca ggttgccttc cccattcgca aagggatttt gaagcgcatt gtggatcata
   110881 atgtggtggt gaaaaacatc agttttacgc tacgagcggg tgaaacactg ggtttagtgg
   110941 gcgagtccgg ttccgggaaa agtacgacgg gactggcgct gctgcgactg attaattctc
   111001 agggcagcat catctttgac ggtcagccac tgcaaaattt aaatcgccgc cagctgttac
   111061 ctattcgtca tcgcattcag gtggtatttc aggatccaaa ctcctcgctc aacccacgac
   111121 tcaacgtttt gcagattatt gaggaaggct tacgggttca ccagccgacg ctttctgccg
   111181 cacaacgcga acaacaagtg atagccgtga tgcatgaagt gggattagat cctgaaacac
   111241 gccaccgtta tccggcggag ttctctggtg gtcagcgaca acgtattgcg attgccaggg
   111301 cattaattct taagccctcg ctgatcatac ttgatgaacc gacatcatca ctcgacaaaa
   111361 cggtacaggc gcaaatattg acgctattga aatcattgca acaaaagcat caactggcct
   111421 atttgtttat cagccacgat ttgcacgttg tccgcgcgtt atgtcatcag gttatcgtac
   111481 tgcgacaagg ggaagtagtg gaacaaggac cgtgcgcgcg cgtgtttgcc acaccgcagc
   111541 aggagtatac gcgtcagcta ctggcgttga gctgacgctt aaaaaggatt gtagtttgaa
   111601 aagggttcgg caattgccac accaaaattt ttcaatcggc atgttgcagc aaactcgtcc
   111661 tggcgattta caaacaggca cggctcacct tcacactcca gcaccgaaca tggaacttcg
   111721 atgtcgctta acgcctggct tagtttatac atcaccgacc atgcattatc accatccggg
   111781 ctaagcaatt taagcgccac caggctgttg tcaccgcacg gtccattttg cggaatcggt
   111841 tcaaccttcg aacctgcgaa accagcagac cagcgatagt tctgcggcag tcgatggacg
   111901 attgagagtt gtaatgaagt cacttatttt ccccggaagt acattcactt cacaatttgt
   111961 ttacatcaat tttaacacat catcaacaat ccgtctttat acagatcgta aagattgatg
   112021 cctcgcctgc gtggcctcta tggctctgat ttaagtaata tctgcgggcg tggtcacgtt
   112081 tgcggggcta tatgtacccg tttctgcgat ctaactcaac ctttttaact acaatgatgt
   112141 gactttttac ataaattgat tttacataaa ataaacatat atcgggggaa tgatagattt
   112201 gtggttgaca tgcatcaaca aaggaagcct tttagcttcc tcgttgtgca atagatcacc
   112261 gttttttcgg tcgactggcg tacagacaga agagaatgga gctgcttgcg cagaatgcaa
   112321 ttgaccaaat catcggccat gcagagttaa aggtcgcaag agaaagcaat gcgccaacaa
   112381 ttgcccctat gccaaaacgg aaggttcctg ccagcgaaga tgccgttccc gccatatggg
   112441 gaaactcatc aagaatgacc gccatcgcat tggatgacac catcgacacg cagcccacaa
   112501 acgccgcaac gccaaccacc agcgaccaga atcccagccc cagcagcgca ctgatgacca
   112561 tccacgctgc cataataaat tgtatccaca accccgagcg gaacatattt aacgcgccaa
   112621 tgcggcgaac gaagcggctg ttaaaaatgg tcatcacgaa caggaaaaca atgtttagtg
   112681 caaagtaata accaaagttt tccggcgcga cgtggttaat ttcaatgtag acaaacggtc
   112741 cggcgcttaa gaacgagaac attccggcaa agctgaaacc gctggccagc atataactca
   112801 ggacacgctt atgacggaac agcgccgcaa agttaccaat agtggtacga atgtgaaatg
   112861 gctgacgacg ctccggtggt aaggtttctt taatcaggaa gaaaatcatt gccgaagcca
   112921 gaatcgccgc taatgccagg atccagaaga tgtaatgcca gctcagccac accagcaccc
   112981 aaccgccgac aatcggtgcc atcaacggtg caatagtggt caccagcatg acaaacgaca
   113041 tcatccgcga gaactcttct ttcgggtaaa tatcgcgcat caaagcgttg ataaccacgc
   113101 tggccgcagc cgccgccagc ccgtggaaga aacgcatcac aatcagctga tcgatggtgt
   113161 ttgccaacgc acacgccacc gcggcggcgg caaacaccag cgtaccgccg agcaccaccg
   113221 gcttacgccc gaagctgtct gccatcggcc cgtagattaa ctgccccaac gcaaagccca
   113281 gaatataagt actgagggtc atctgcgtac tgcccgcagg tacgccaaac tgcgctgaaa
   113341 ttaccggtag cgcgggcaga tacatatcaa tcgacagcgg catcaacatg gccagcaggc
   113401 caaggataaa aacaatagca aacgacgaat gctgtcgggt ggtcacaacg ggctcctgaa
   113461 agtcatggaa aagttagacg acgctggcaa tttcttcttc agttaacgga cgatattcac
   113521 cgggggctaa atcagcatcc agcgtaatac cgccaatacg ttcacgatgc agctcaacca
   113581 cgtggttacc cacggcggcg aacatgcgtt tcacctgatg ataacgccct tcgctgatgg
   113641 tcagacgaac ctgcgttggg gtaatcactt ccagcaccgc aggcttagtg agatcttttt
   113701 cgttatgcag ctgcacgcct ttagcaaatt gctctgccgt atcgtcagct acaggtgatt
   113761 ccagtgtcac cagataggtc ttctcgcaat gatggcgcgg agaagtaatg cggtgcgacc
   113821 actgaccatc atcagtcatc agcaccagac cggtggtatc gatatccaga cgtcctgcgg
   113881 cgtgcagttt ccaggctacc ggttcatcca gaaaatagag caccgttggg tgatcagggt
   113941 cgtccgtgga gcaaacatag ccctgaggct tattgagcat gaagtaacgt ggaccatgtt
   114001 gctgcgccag cgggttgcca tcgtaagcga catcatgttc aggaagcagt ttgaacgctg
   114061 cattacgaac aatttcgcca tcgacggtga cacgattgcc gcggatttca cgcccggcaa
   114121 tagcacggct aacgccgagt tgctgtgcga taaatttatc aagtcgcatg tgtgtgattt
   114181 tgcctgtaaa aacggaggtc gggcattgac ccgaaaatct gaactgttgt ctgcccagta
   114241 tagcggtcta ataacatccc tcaagggaaa aagatccatg gcatactatt agcagaataa
   114301 tctacctatg cgagaccatg atttttacac tccgcccata tcagcaagaa gccgtggatg
   114361 ccacgctcaa ccattttcgt cgtcataaaa cccctgccgt tatcgtgctg cccaccggcg
   114421 caggtaaaag cctggtgatt gccgaactgg cacggctggc gcgtggtcgt gttctggtgc
   114481 tggcacacgt caaagaactg gtggcgcaaa accatgcaaa gtatcaggcg ctggggctgg
   114541 aagccgatat ttttgccgct gggttaaagc gcaaagagag ccacggtaaa gtggtatttg
   114601 gcagcgtgca gtcggtcgct cgtaatcttg atgcctttca gggtgaattt tcgctgttga
   114661 ttgtcgatga atgccaccgt attggtgacg atgaagagag ccagtatcag caaatcctca
   114721 ctcacctgac taaagtgaat ccccacttac gcctgctggg gctgactgcc acgccttttc
   114781 gattgggcaa aggctggatc taccagttcc attatcacgg catggtacgc ggcgatgaga
   114841 aagccctttt ccgtgactgc atttatgagc tgccgctgcg ttatatgatt aaacacggct
   114901 atctgacgcc gccagaacga ctggatatgc cagtagtgca atacgatttc agccgcttgc
   114961 aggcacagag taacgggctg ttcagcgaag ctgatctcaa ccgtgagctg aaaaaacagc
   115021 aacgcattac gccacatatc atcagccaga tcatggagtt cgccgaaaag cgcaaagggg
   115081 taatgatttt cgccgccacc gttgaacacg caaaagagat tgtgggatta ctgcctgccg
   115141 aagatgctgc actgattact ggcgacaccc ccggcgctga gcgcgatgtg ttaattgaag
   115201 attttaaagc ccagcgtttt cgctatctgg tcaacgtcgc agtactgacc accggatttg
   115261 acgccccgca cgtcgatctt atcgccattc tgcgccctac cgaatcagtg agtctttacc
   115321 aacaaattgt cgggcgcggt ctgcgtctcg ctccgggcaa gactgattgc ttaattcttg
   115381 attatgcggg taatcctcac gatctctacg cgccggaagt tggtacacca aaaggcaaaa
   115441 gtgacaacgt tccggtacag gttttctgcc ctgcctgcgg ttttgccaac accttttggg
   115501 ggaaaacgac cgccgacggg acattgattg aacactttgg tcgtcgctgt cagggatggt
   115561 ttgaagatga cgacggtcat cgcgaacaat gtgacttccg tttccgtttt aaaaattgcc
   115621 cgcaatgtaa cgcggaaaac gatattgccg ctcgccgctg ccgcgaatgt gacaccgtac
   115681 tggttgatcc agacgatatg ttaaaagcgg cgctacgact gaaagacgcg ctggtattac
   115741 gctgtagcgg catgtcttta cagcatgggc atgacgagaa aggcgaatgg ttgaaaatca
   115801 cctattacga tgaagacggc gcggatgtga gtgagcgttt ccgtctgcaa acgcccgccc
   115861 agcgaactgc cttcgagcag ctttttatcc gcccgcatac gcgcacaccg ggcatccctc
   115921 tgcgctggat caccgccgcc gatatcctcg cccagcaagc cttattgcga cacccggatt
   115981 ttgtcgttgc ccgcatgaaa ggtcagtact ggcaagtgcg tgaaaaagtg ttcgattacg
   116041 aaggtcgttt tcgtcgggcg cacgaattac gcggttaatg gtagttttga ttgatgtata
   116101 aagcgattga gtatagaatc tcgcccgctt ttgcatacgc aaagcagatc acttacctgt
   116161 tgctgggtcg cctgtagcag gattaattta agagagaaag aaatgtttac tatcaacgca
   116221 gaagtacgta aagagcaggg taagggtgcg agccgccgcc tgcgtgccgc taacaagttc
   116281 ccggcaatca tctacggtgg caaagaagcg ccgctggcta tcgagctgga tcacgacaaa
   116341 gtcatgaaca tgcaagctaa agctgaattc tacagcgaag ttctgaccat cgttgttgac
   116401 ggtaaagaaa tcaaagttaa agctcaggac gtacagcgtc acccgtacaa accgaagctg
   116461 cagcacatcg acttcgttcg cgcttaattg ctgaataagt tgtaaaaaac cccgctccgg
   116521 cggggttttt tgtatctgca gattatgcct gattacggta ttgctatttt ttgcaggcca
   116581 gataaggcgt tcacgccgca tctggcattc agaacacaaa accgattaat tgccgccaga
   116641 cgtccggcgc tgcaattggt cacgcaaatt cggcggcgtg cctttaatgg tcagggtatc
   116701 ggttgccgga tcccagaaga tgcgttcacc taacagcatc gcatcaaagt taatagtcaa
   116761 gccaccgccg ctaccggcaa acttcgtcaa ctgacgcagt gtgctacggt ctgccgggaa
   116821 gctctcttcc agttcgtagc ctttttcagc cgcaaactcc gtgaaactca cttcgctgac
   116881 gcctgccagc tctttcgaca gcgactccag ttcgatctct tcgcctgcct gcagctgctc
   116941 attacagtag ctataaacct gctggcgcac gttctgtcgc tctgctttat ccagttgtgc
   117001 ttcggcagtg aaatcatcaa ccgcttgcaa cagcccacgg ttttgcgctt tcgcgtttaa
   117061 cccttcgctg gccccgagga aatccataaa gaaatccgcc actttgcgcc ctactcgccc
   117121 tttcaggaaa gtgagatagc gggtggactc tggattggtt tcccattcgg ttaaatcgat
   117181 acgcgcaaca atatccgcat gattgatatc aagataatgg gttggattga tgtcgagatt
   117241 ttcgttaacg cgcatactgc tcaggttgct cagaactgcc accagcagat actccaccgc
   117301 cagataacgg tagtggcaaa acagcacgaa tccaccgtca gcaaaaggat atttcgctaa
   117361 ttcgtcacgc aggcgcccgg ttgccgcgcg gctaaatgcc agaaagtcct cttcgccctg
   117421 acgctgtaag cgcagcgtct gcgccagttc actctcttcg ctaaacaagc cgtaagcttt
   117481 atttttggcg ctatagaccc gatgcagttc tgccaccatc tcaacgacgg tttctgtcgg
   117541 ttccagcaat gaatcgcgca acaccagctc aaggttctgc tcatcacgct tgataagctg
   117601 gtgcagagca atctggttga tatccagact catgataaac tctcctttaa gaccgggcgg
   117661 tattcaacca ccgccggtta agcgacgcaa taaaagatgg cggtcatttt acagaaggca
   117721 gcgtaacgag aatgatttaa cgcataaaaa agcagaaaaa aaaccgttgc tacggtaata
   117781 tgttgccctt tcatcaacta actgatttcg atttatgcca caaatttccc gctacagtga
   117841 tgaacaggtt gaacaattgc tcgcagagct gctcaacgta ctggaaaaac ataaggctcc
   117901 gaccgacctt tccctgatgg tgttaggcaa catggtcact aaccttatca acaccagcat
   117961 tgccccggcc caacgccagg caattgccaa ctcttttgcc cgcgccttac agtcctctat
   118021 caacgaagac aaagcgcact aagggaaaca gataacaggt tatggtaact catcgtcagc
   118081 gctaccgtga aaaagtctcc cagatggtca gttgggggca ctggtttgca ctgttcaata
   118141 ttctgctttc gctcgtcatt ggcagccgtt acctgtttat cgccgactgg ccgacaacgc
   118201 ttgctggtcg catttattcc tacgtaagca ttatcggcca tttcagcttc ctggtgttcg
   118261 ccacctactt gctgatcctc ttcccgctga cctttatcgt cggctcccag aggctgatga
   118321 ggtttttgtc cgtcattctg gcaacggcgg gaatgacgct attactgatc gatagcgaag
   118381 tctttactcg tttccatctc catcttaatc ccatcgtctg gcaactggtt atcaacccag
   118441 acgaaaatga gatggcgcgc gactggcagc tgatgttcat cagcgtgccg gttattttat
   118501 tgcttgaact ggtgtttgcg acgtggagct ggcaaaagct gcgcagcctg acgcgtcgtc
   118561 gacgcttcgc gcgcccgctg gccgcattct tatttatcgc ctttatcgcc tcgcatgtgg
   118621 tgtatatctg ggccgatgcc aacttctatc gcccgatcac catgcagcgc gctaacctgc
   118681 cgctttcgta cccgatgacg gcgcgacgtt ttcttgagaa gcatggtctg cttgatgcgc
   118741 aggagtatca acgccgtctt attgagcaag gtaatccaga cgccgtttcc gttcagtatc
   118801 cgttaagcga actgcgctat cgcgatatgg gcaccgggca gaatgtgctg ttgattactg
   118861 tcgatggcct gaactactca cgcttcgaga agcagatgcc tgcgctggca ggttttgctg
   118921 agcaaaatat ttcgttcacg cgccatatga gctccggcaa cactacagac aacggcatct
   118981 ttggcctgtt ctatggcatc tcgccgagct atatggacgg cattctgtcg acccgtacgc
   119041 ctgcggcatt aattactgcg cttaatcagc aaggctatca gctggggtta ttctcatcag
   119101 atggctttac cagcccgctg tatcgccagg cattgttgtc agatttctcg atgccgagcg
   119161 tacgcaccca atccgacgag cagaccgcca cgcagtggat caactggctg ggccgctacg
   119221 cacaagaaga taaccgctgg ttctcgtggg tctctttcaa tggcactaac attgacgaca
   119281 gcaatcagca ggcatttgca cggaaatata gccgggcggc aggcaatgtc gatgaccaga
   119341 tcaaccgcgt gctcaatgca ctgcgtgatt ctggcaaact ggacaatacg gtggtgatta
   119401 tcactgccgg tcggggtatt ccgctgagcg aagacgaaga aacctttgac tggtcccacg
   119461 gtcatctgca ggtgccatta gtgattcact ggccaggcac gccggcgcag cgtattaatg
   119521 ctctgactga tcataccgat ctgatgacga cgctgatgca acgcctgcta catgtcagca
   119581 cacctgccag cgaatattcg caaggtcagg atttgttcaa ccctcaacgc cgtcattact
   119641 gggttactgc agcggataac gatacgctgg caattaccac cccgaaaaag acgctggtgc
   119701 tgaacaataa cggtaaatac cgcacttaca acttacgtgg tgaaagagtg aaagatgaaa
   119761 aaccacagtt aagtttgtta ttgcaagtgc tgacagacga gaagcgtttt atcgctaact
   119821 gattaattat aaatcagtta gcaaaatatc ttacttgcaa tcggtgtgga aaacggtagt
   119881 attagcagcc acgagtcggc acgtagcgca gcctggtagc gcaccgtcat ggggtgtcgg
   119941 gggtcggagg ttcaaatcct ctcgtgccga ccaaaaatcc caagaaaaaa ccaaccttta
   120001 cggttggttt tttttatatc tgcaattaat tcgataaaca gaccgtgaca catcacagcc
   120061 tgtttatttt ttgttatcag aacgtccaga ccacacccgc ctgagtattc cacggcgatt
   120121 ctacccctgc gccattgcca tagctgactg acaaatgacc gcttaacgtc ggggtaaacg
   120181 atgaccttat cccagcctga taaacgccac gggttccagc cacatcatta ttaaatttgc
   120241 catcgtcatt aactttcacc tggttagaat cggcgtattc ctgacgcacg gcggctttca
   120301 gtcagggttc cagcgtcgta ccgttttgca ggtccatgtg atagcttacc gccgttcccg
   120361 cttcagcgcg taatatccgg gtatttccca catccgcgcg catgccgttt gataacgtgt
   120421 agtcctgacc atctgtggta aagccggtaa aggccagata gggtctaaca ctccacaatc
   120481 cgtcaaccca acggaacccg ctctcgacat gagcacccgc gccgttacta ttgtaatcgc
   120541 caaacgctgt tgccccatta ctcatcttgc aatggatggt gttggcaaaa cggtcaactt
   120601 tcaccactcc atcaacatag gcaccgttct gatgctccca accggcataa gcccccaggg
   120661 tatagctatc gacattgcct ttgccgccgc gatcaaaacc aatatcagaa tgagagtaac
   120721 caaagaacaa gccgcgaatt gtgctggttt cttcacggga gaaacggcta tcgataccga
   120781 gcgtcagccc ggtcaatgtt tgctcaaagc cagcgcccgc atcagtggtc acgttgttgc
   120841 gggtgttaat tgccgaactc cacatcgccg tatcgtaatt aacgcctttt acgctaccaa
   120901 gacgctcacg cacggtgtcc agttctgcat caaataccag cggttgtgct gccgccatat
   120961 tcagcacatc agtggttgaa ggggtaattt gcgcgcgatt ctctgccaaa ctccagctat
   121021 ggttgccatt atccagcaag gtatattcat acgtaccgat atcaacaacg cctccggcat
   121081 tgcccaacgt aaatgcagca tcaccgccgc ccgttgttac cagtgtaagg ctatctcctg
   121141 ctgccgggct ggcaccggtg tccgtcacga atattttgaa atcacctgtt gcctgaccgg
   121201 tgacgttgag ctgatcgctc tgatgattag ccatatcggt acgcatataa aaattgccgt
   121261 ttcccgacag ggtattggtg gtcaacgtaa tgaaattttc cgcacttgcc gtcactgatg
   121321 aacgagtcac tggctcatcc atcataatca catttgcgtc agacatcgca aggttggcta
   121381 agttgaggag ggtgttttgg ttcgtcgtag tgatatcggc aatgatggtc catacgctat
   121441 tttcgagcga aacgtccgct ttgctggtat ccacggcacc atgcgttcta aaagaagcgc
   121501 cctcagaaac cactacctta cccaccaaca ttgcgggtgc ataatttatt tgcggcttca
   121561 tgacctcaag aatgccatca ttccctctga ctgaaacgtt aaccattgtg ccagcccaga
   121621 cgttagcgcg gccattgttg ataaccatat tttcagagat ggcttttgag gaatacgtga
   121681 tacttccatt ctgatctgat cgaccgagat catataccgc atttgcctgc actttcgtac
   121741 cagtatcctt tcccagcgat tgcatagtgg catgctcatc aaggatagta tcaatggcct
   121801 gcgtgtcctc cataacaatg agcccggaac catcatccag ttcataattt tttgacacac
   121861 catcttttat actaaattgg cctttactgt ttggaccact cacttccagc gcattcgttg
   121921 agacaattaa ttttccgcct gcttttttat caacgccagt tacagtcccg ccatccataa
   121981 cctccagtaa gccgccacta tctacagtgg tattataagc gaagtcattt tcttcaactc
   122041 gcaaacttcc gccgttttcc aacaacatat tattagcaat accattcttg atatcgaact
   122101 gaccgagacg gtttgttccg aatacctcca tggcccgcgt gcttgcttta atagcaccgc
   122161 ctgctttctg atctaccgca atcgctaatc ccccctcttt aacctccagt aatcctccct
   122221 tttcgatagc ggcaaggacg gtaatcccat ctttttcaac gattaagcgc ccgcctttaa
   122281 tcgtgggatc attcgctgcg ccataaacct gtagcacacc attattgagg gtagtctggt
   122341 ttgccgcgcc acccatttga acaatttgat aaccgtcatt taatactgag tattctgcgg
   122401 taccattcat ttcaatgtac tgataccctc ctttaatttc agtattacta cttacaccaa
   122461 attcttttat atgctgttct ccgccaggat tgattttcgt attattggcg gtcccataaa
   122521 ccagctggat atctttttcc aggacaacac catcaactgt ctcaccatac tcaactgttg
   122581 atgccaatgc tatgggtgaa tataacgctg tagccatcag aacagatatt gcggaacgac
   122641 aaagagaaac agaaccagat tgatgaattg agctttcatc ctatgaaatt aattgctgtt
   122701 aaaagcattg ggtacggaaa atacccatag ctccataccc ggagtcagtt tttaaaaact
   122761 gtttaaagaa atgcacaagt attgtgattg attttttagt tgtttttctt gatgagaagc
   122821 tgatgcaaaa ttccgtcttt ataatgaaaa tgatgccaaa gcgaacgaca aggttgtagt
   122881 tttcactaca tgtccataca taaaatgggg taacattcac gcgcctggta gcgttaccaa
   122941 cgctacgctc aaacataatg attctaataa aacctcagga gactactatg cctgaagcaa
   123001 cgccttttca ggtgatgatt gtggatgatc atccacttat gcgacgcggt gttcgtcagt
   123061 tactggagct tgatcctggc tttgaagtgg tcgccgaagc gggcgacggc gcgagcgcga
   123121 tcgatctggc gaatagactg gatatcgacg tgatcttgct ggatctcaat atgaaaggta
   123181 tgagtggcct ggataccctc aatgccttgc gcagggatgg cgttaccgcg caaattatta
   123241 tcctgaccgt atcagatgcc tccagcgatg tctttgcact gatagacgca ggcgcagacg
   123301 gttatctgtt gaaagacagc gacccggaag tattgctgga agcaattcgt gctggagcga
   123361 aaggcagcaa agtctttagc gaacgcgtca atcagtactt acgtgaacgt gaaatgtttg
   123421 gcgcggaaga agatcccttc agcgtgctga cggagcgcga gctggatgtt ctgcacgagc
   123481 tggcacaggg gctgtcaaat aaacagattg cctcggtgtt gaatatttca gagcagacag
   123541 taaaagtaca tattcgcaat ctgctgcgca aactcaatgt ccgctcacgc gtggcagcca
   123601 ccattctgtt cctgcaacaa cgcggggcac aataaaaata gcccgatggc atcaccatcg
   123661 ggcctctttt tatttactct cctgcggcga caaatgttgc atcgcctgcg cgatactacg
   123721 ttcaatcacc gcacggcgag tatcgttggc aggtaagagt ttcaacatca tctcccacgc
   123781 ggcaacggct tcgccaaatc gctgctgctc aaaggcatta aacgcataca tgcttaacac
   123841 acggatattg ctgtggtcgc ttctcaccaa ctggcgcagc agttcaccac cgaggcggtt
   123901 gtcgttggga tcagatgaac gtgtcaacgc ttcagcataa cccagtgcgg catcgctgtt
   123961 tttcggatcg aggcgatacg cagtagcgta tgcatcggtg gcgatactag cgttacccag
   124021 cgccatgcca acgcggccca acataatcca gccttctata tctcccggat ttttttgcag
   124081 ttgagtacgc atccccagcg caagacgcga catctcttct tcgttgagcg gatcggcttt
   124141 cggatccagc gccctgtcca gcaacgccgg agcctgtgcc gtggcctgct gccagatttt
   124201 cacctgctga taattgccag tctggtagta gctgacgcca gccacaatta acgccaccac
   124261 aatacccggc agataaacaa tatatccggc acgcttacct tcctgcacgc tttgttcagg
   124321 aaacgcttcc ggcactacgc gtacccgacg ccgcgagcgg gcgtatatga cccaaccgcc
   124381 aatgccaata gccactaccg gaagcaccca cagcagcacg gtcagcggcg ttaacggcgg
   124441 atcgtaagtg acgaagttgc cgtaacgcgc caccatataa tcgacaatct cttttttact
   124501 tttaccttcc tgcatcagtt catacacttt ctgacgcagg tcggtggcaa tcatcgagtt
   124561 ggaatcggca atgctgttgt tctggcattt cgggcagcgc agttcttcag tgagctgacg
   124621 gaactgttgt tcctgtgctt catctttaaa ctgcaacacg tcgatggtcg ccagtgctga
   124681 gccggagatc atcagcatca gcacgcccaa taaaaacctc attgtgcggc ctccttactg
   124741 tatttctccc acagcggctt gatctcttct tcccagacgc gaggattgag atcgcccgca
   124801 tggcgatagc gaatgatacc gttgccgtca ataaggaagg tttctggcgc gccatagaca
   124861 ccgagatcca gccctaacat gccgtcgcca tcaaacaggc ttagcgcgta aggattgccc
   124921 agctctttca gccagctgat tgccttctgg cgatcgtctt tatagttcat gccgaccacg
   124981 cgaatgccct gcgctgaaag ctgattcaga tattgatgtt ccgcacggca ggtcggacac
   125041 caggtcgccc agacgttaag cagcactggt ttgccctgag tcagcacatc cgcctgataa
   125101 aactgccccg gattgtccag tgattcgaga cgaaacttcg gcacaggctt gccaatgagc
   125161 gccgattcca gattggtcgg atcatcccct tcggcattac gcgccagctg ccacagcagc
   125221 gccgcggcaa tcgccaggaa gataatcaac ggaattaaca atactttgcg cttcatacgg
   125281 cctccggcgc agttttttgc ggactcacgc gcttacgata gcgaggatca aacagacaca
   125341 gcagtccgcc caacgccatc atcagcccgc ccgcccaaat ccagcgaaca aatggtttgt
   125401 agtaaagacg cacggcccac gcgccgtttt ccagctcttc accgagcgcg gcgtacaggt
   125461 cacgcgtgat gccgccgtca attgccgctt cggtcatcat cgacccggca gtgttgtaat
   125521 aacgtttttc cgcatacagc accgtttccg gcttgccatc gcgcgttacg ccgatagtcg
   125581 ccacaccgcc acgccagttc gggccagtca cctctttgac atcacggaag gtgaagcgat
   125641 attcatgaat atcgacgcta tcgccggact tcatgcgcac atcacgctca acgctatagt
   125701 tctggctaaa ggcaatacca acaattgtca ctgccagccc caggtgagcc gccaccattc
   125761 cccaataact gaaggtggtt ttcgtgccac gtgaaatacg cagcgcagct tccgcaattg
   125821 ccagcacagc aatccagcag gccattgcca ggccgagcac cgtcatcgcc acaactttgc
   125881 tttcgaacag ccacggcagc agcagcgaca gcaccagcgt tgagatgaag gcgataatca
   125941 ataaattgcg gattttacgt gggcgatcgc gcccccagcg caccagagga ccgacaccaa
   126001 gcagcagcgc aaacggcacc atcagccagg taaacatggt gttgaagaac ggttcgccaa
   126061 tcgaaatact gcccagtccc agttgcttgt gcaccagcgg cagcagcgtc cccagtaata
   126121 ccaccagcat cgcggcgacc agcaaaacgt tgttcgctaa cagcagagat tcccgcgacc
   126181 acagcgcatt gtttacgcgt gagcgaactt tgtgtccacg cgcggcaaac agcagcagcg
   126241 aaccaccaat caccagtacc ataaaggcga ggataaacat accgcgtgcc ggatcagagg
   126301 caaacgcgtg taccgatacc agcacgccgg aacgcaccag gaaagtcccc agcagacaca
   126361 acgagaaggc actgattgcc agcagtaatg tccacgcttt gaagctggcg cgttgttcag
   126421 tgaccgccag tgagtgcatc agcgcagtcc ccaccagcca cggcataaac gaggcgtttt
   126481 ctaccggatc ccagaaccac cagccgcccc agccgagttc gtaataggcc catgcggaac
   126541 cgagcacaat gccgagcgtc aagaagatcc acgccgccag cgtccacgga cgagtaaaac
   126601 gcgcataagt gctgtccaga cgcccgcaca acaaagaagc aatggcaaaa gcaaacgcca
   126661 ccgagaaacc cacgtacccc atataaagca gaggcggatg gaagatcagc cccggatcct
   126721 gtaacagcgg gttaagatcg cgcccttcaa tcgggaagtt cggcagcgtg cgtgagaatg
   126781 ggttagaggt aaagagaatg aacagcaaaa agccgacgct gaccatcccc attatcgcca
   126841 gtacgcgggc cacaatatcc agcggaatac gctgactaaa aatcgccacc gcaaaggtcc
   126901 agccgctcat cagcagcacc cacagcagga gcgagccttc atgcgcgccc caggtagccg
   126961 ccacgcgata ccacaccgga agctgggtat tggagttgct ggcaacatag gtgacggtaa
   127021 agtcgttgac cacgaaagca ttgaccagca ccagaaatgc gccagccaca gacataaaca
   127081 gcagccaggc aaacaagcgg gaagacgcca tcatgcgcgc atctccgcgc gccacgcccc
   127141 atagcggata cacggacagc agcagcgcaa tccctaacgc caggcacagc agcccgtttc
   127201 caatttccgg catcatgatg ctgggtcctt ataaacactc gccgggcgac ggtggttagc
   127261 ttccatcgct ttctcaactt ctggcggcgt gtagttttcg tcgtgtttcg ccagcacttc
   127321 tttcgcgagg atatgattgc ctttttccag ctcgccctgc accacaacgc cctgcccttc
   127381 acggaacaga tccggcaaaa tgccttcgta agagacatcc actgagcctt cagcatcgta
   127441 aatagtgaag gtcactttca gcgaattggg atcgcgctgc acactacccg gcatcaccat
   127501 cccgccaacg cgcagacgct gaccgacttc cggcatttgc tgagtttcac gcttgccgta
   127561 gagaatttcc cccggcgtat aaaagagatc gatattcgag cgcagcgcat atagcaccag
   127621 accgatagtc agcgccagcc ctgccaacac ggcacaggca atccacaagc ggtttttacg
   127681 gcgaatattc atgcagcctc ctgctgttgc gcagcacgta aacgcgcctc acgcgcccgc
   127741 tgttgcgcca caccacgcag aattgcgcga tgttgcatca ccgagtgcac gaccaaaacc
   127801 accagcggaa taacggtcat caccaccgcc agccagacaa aaaaggcgta accgcccatt
   127861 gcgaaaaatt cattccagga agcaaatgca ggggtcattt acggcctctt ttcagtatca
   127921 gttcactcac ccacggacgg cgtttttcca tcagcaaaat caaattacgc atccgcatca
   127981 gcgtcagcgt ggcagacagg agcaggaagc caaaaatcga ccagcgcagc ggcgaacgca
   128041 tcgccggatc gatactttgc tgcatccgcg ttgatccctg atgcagggtg ttccaccact
   128101 ccacggagta atgaataatc ggcagattca ccacgccaat cagcaccagg atacctgccg
   128161 cacggcccgc cagacggcgg tcgtcgaagg cgtgccacag ggcaatcaca cccacataca
   128221 aaaaaagcag caccagttca gaagtcagac gtgcatccca tacccaccag gtgccccaca
   128281 tcggttttcc ccatgcagag ccggtaacca gggcaataaa ggtaaacacg gcaccaatgg
   128341 gggccatcgc cgccaccgcc aggttggcca ttttcatctg ccagacaagg ccaataaacg
   128401 ctgccactgc cattgatgca taaatgccca tcgaccagat cgccgcaggc acatgcaggt
   128461 agataatgcg gtagctattt ccctgctgat aatcagccgg agcaaagccg aatccccaga
   128521 tccagccgac ggtaagcacg accacactgg caattgccag ccacggtata aaccagccac
   128581 agatttgata cagccgtggt gggatcgcca gttgatgcag tgttttccac atagtttcga
   128641 taccagactc gaacaaaaat cagtaatcca gcgttattga atgctgattc gtaacgctgc
   128701 cgccgtcgca aaaggactta atgtcgcggt gcctgccagc aacgcgccta aaattgccag
   128761 atacccgtca acgggcaaat gcatggaagc cgcgtccatc gcggcggtgg cgaagatgag
   128821 taatgggata gtcagcggta acaccagtat gctgagcagc acaccaccgc gcttaagtcc
   128881 cactgtcagc gccacgcccg gtgcaccgag aaagccaagc gtaggcgttc ccagcagcag
   128941 cgtcagcgcc atcacttgcc agccataaac atccattccc agtagcattg ctaccagtgg
   129001 cgaaagaatg agtaacggca gaccggttac catccagtgc gccatcacct tcgccagcac
   129061 aacggcgggc aagggtaacg gcaacaacat caattgttca agactgccgt cctgcaaatc
   129121 gtcacggaac agtcgttcca gcgccagcaa ggatgaaagc agcgcagcaa cccagataat
   129181 gcccggtgca atacgcgcca gcagttgcgg ctccggaccg atactgagcg gaaaaagggt
   129241 aattacaatc aggaagaacc acagcgggtt ggcgatttcg gcgctatggc gaaacgctac
   129301 acgcagctca agacggaaaa tgcgccagaa catcatgcgg ccctcgtttg cgtcagtgaa
   129361 atgcggcgaa ttttactttc agcaacgttg agcggctggt gggtagtcag aatcacaatc
   129421 cccccctgct ccgtatgctg cgccatacgc tgggtcagac gatcgacgcc gttaacgtca
   129481 atcgcggtaa aaggctcgtc gaggatccat aacgtggcac gggtcagcca cagacgcgct
   129541 aaagcgacgc ggcgttgttg cccggccgag agctgattta caggaatatc ttcgaatccg
   129601 gcaagcccgg cctgcgccag ggcttccaga cattgtgcgg tatcgccatc gcgatgataa
   129661 aagtgcagat tttctaacgc cgtcagccgg gttttgatcc ccggctgatg gcctatccat
   129721 aacaggtttt gatggtagct gtcgcgtacc tgatgcaagg gctgcccttg ccagagaacc
   129781 tcgcctgcgt cagggcgaga caaccccgtc agcaaacgga gaagcgttgt cttccccgcg
   129841 ccgttgctac cggtgatttg tacccactct cctgcgttca gcgtaaatga caagccacta
   129901 aataaggttc gttcatcccg ctcacaaagt aactctctgg cttcaagcat acccacgcaa
   129961 taaccctgtt aaaaacctgg ctcgacttca cgcatatcgg gcagcttgtg cgctatccct
   130021 ttatggcaat caatacaggt ttgcccatct ttcaccgcct ggtcatgcat cttcgcggca
   130081 accgatttct gggcggttgt atccatatac tcgaagttgt gacagttacg gcactcctgc
   130141 gagttattgt ccttcatgcg ccgccactca ttctgtgcca tcgtcagacg atgagcttca
   130201 aatttctgcg gcgtgtcaat aacgccaaaa attttaccat acagctcttt acttgctttg
   130261 agcttgcgta tcatcttcgg cacaaactcg tgcggaacgt gacaatccgg acaggtcgca
   130321 cggacgccgc tacggttgtt gtagtgcacg gaatccatgt attcctgata caccgtgttg
   130381 cgcatttcgt ggcagctaat gcagaactct tcggtattgg ctttttccat cccggtgtta
   130441 aagccacccc agaagacgat gccgccaaca aaaccgatca acagcagcgt ccccagcgcc
   130501 agacggctgg gggtacgcca ccatttccac aggcgcttaa tcagaccagg cttacggtca
   130561 gaatttccca taataacctc ttatttcccg taaccttttg atggggtaaa ggtattcccc
   130621 acgattggcg cggtatcggc ctgcggtacg tgacattgca gacagaaata acgacgcgga
   130681 gccacttccg cgcccacttt gccgtcgctg tccataaagt gagtaggact gatacgcggc
   130741 gcgccagtgg tgcgataact ttcgacaccg tggcactgca agcagcggtt ggtattggtc
   130801 gttacctgat aaccttcaac gctatgcggg atcattggcg gctgattcac atagttcagc
   130861 ggcatccgtt cctgctcttt tggcatccga atggcccctt cctgtgtccc ggatacttcc
   130921 ggcgactggc taaaatcgac gccattagcc gcccaaaccg cgccgcttac caccagggcc
   130981 agcatcgccg tccattgaca cagcgctttc ttcaggtcat ggcttttcat gatttcgctc
   131041 ccgaactcca tcgtgtagtt attgtaaata catcctcaga acagacatcc acgcagcgac
   131101 cgcacgtcat gcaatcgcgg ctggtgacct gcaccgggct ttgttcatcc agcaccgggg
   131161 cacgtagcac atgcggttcc gggcaaacat gaaaacaatc catacagcgg ttacatttct
   131221 gccgatcggt ggccgcaacg gtaatcacac ctttgctacc cagcacgcca tacagcgcgc
   131281 caaccggaca aatgtgcccg caccagccgt gttcaacgac cagtagatca aataaaaaca
   131341 gcgcgagaat aagcagcgcg ccgctgccga agcccattac caggctgcgc cccatcagag
   131401 atacggggtt gatccattcc cagatgagcg tgccagttaa ggccgatccc agcagaatga
   131461 ccaccaacag cacgtagcga atgtggcgag ggatcgtcgc agactgattg aggtcaaagc
   131521 gcctgcgtaa ccagttcgct aagtcggtaa tcgggttcag cgggcagacc cagctgcaaa
   131581 ataatcgctt tcccgccagg gcgtagagca cggtgataat caccgcaccg gtcaacgcca
   131641 ccgtggcagg cagatgacca ctggcaagac tttgcagcgt catcagcgga tcggtcagcg
   131701 gaacggtgtc gaataacagg ctactgctgt agttgccgtg caagatccac acaccaaacc
   131761 atggaccgct caaaaacatc cccagcacga agaactgaca aaggcgacgt aacaccagcc
   131821 aacggtgact gcgccaccag ccttttttct ccagcgcctc gcgcccggcg tcacgtttac
   131881 gatttgccat tgttcccctc cagccaaccg aagcggtaat ggtgacctaa ctcccctttc
   131941 gccagtgaca gcggtaacac cttgattgcc ggttgttcca gcacgcatac tttttcgcac
   132001 ttaccgcaac cggtacaggc gtcgctgtga accgtcggca gaaagcgggc gtgcttaccg
   132061 gtacgcgtgt tgcgctccag ctccagggtg atggcctcat caattttcgg gcattcgcga
   132121 taacaaacat cgcagcgcag cccctgaaag ttgagacagt tttcctggtc caccagtacc
   132181 gccagcccca tccgcgcgtc gtcgatcgat tcaatctcac gatccagcgc accgcttggg
   132241 cacactttgg cgcacggaat gtcctcacac atttcgcaag gaatatcccg tgcgacaaaa
   132301 tatggcgtgc ccgccgacag accagaggcc agcgtcgcca gttttaaggt gtcgtaaggg
   132361 caagcctgaa cacactgacc gcaacgcaca caggcactgg caaaggcgtt ctcgtttatg
   132421 gctccgggcg ggcgcaaccg cacgccagat gcgcgtgcgg tttgctgttg taaccccagc
   132481 gccacaccca cggcagccag cccgcctgct gtgcgaacga catcgcgcag aaagcggcgg
   132541 cgaccatttt gaggtttcgc tgaccgggac ataatggctt acaccttctc cagtttgact
   132601 gcgcacttct tgaagtccgt ctctttcgag agcggatcgg tcgcatccag cgtcagtttg
   132661 ttaaccagct gtgcggcgtc gaagaacggc atgtacacca ggccctgtgg cggacggtta
   132721 cgaccgcgcg tttcaacaat cgagatcact tcaccacggc gagaaaccac tttcactttg
   132781 tcgccacggc gcagatcgcg cgctttcgca tccagcgggt gaataaacaa gaccgcttcc
   132841 gggaaggcgc ggtgcagttc cggcacacgg cgagtcatac tgccggtgtg ccagtgctcc
   132901 agaacgcgtc cggtagagag ccacaggtcg tactcttcat ccggtgcttc cgccgccggt
   132961 tcgaacggca gtgcgaagat caccgctttg ccatccggtt taccgtagaa cttatagcct
   133021 tcgcccgctt tcacgtacgg gtcgttacct tcgctgtaac gccactgtgt ttctttaccg
   133081 ttcaccaccg gccagcgcag accgcgcgct ttgtggtagt catcgaacgg cgcgagatcg
   133141 tgaccgtgac cgcgaccaaa ccatgcgtac tcttcgaaca gccctttttg cagatagaag
   133201 cccagctcgc gggattcatc gttcagctga tcttccgcca gttcggatac cgggaatttg
   133261 ctcacttcgg gggtggcata cagaacttcg tacagcgttt tgccacgcag ttccggtttc
   133321 ttcgccagca gctcttccgg ccatacttct tcagttttga agcggcggga gaactggact
   133381 aactgccaga gatccgattt cgcttcgcct ggcgcctgta cctgctgacg ccagaactga
   133441 gtacggcgtt cggcgttacc gtaagcgccc tctttctcta cccacattgc ggtcggcagg
   133501 atcaagtcgg ctgccagcgc actgactgtc ggatacggat cggagacgat gatgaagttg
   133561 cgcggatcgc gccagcccgg catacgctct tcattaatgt tcggcccggc ctgcatgttg
   133621 ttggtacaca tggtccagta aacattcagc ttgccgtctt tcagtgcacg gtcttgtgcc
   133681 accgcgtgca gaccgatttt cgccggaatg gtgccgctcg ggatattcca cttcttctcg
   133741 caaatatcac ggtgtttctc gttagtcacc accatgtccg caggcagacg gtgagcaaag
   133801 gtgcccactt cacgcgcagt accacacgcg gaaggctgcc cggtcaggga gaacggaccg
   133861 caacccggct gggaaatttt gccggtcagc aggtgcaggt tgtagaccag gttgttggcc
   133921 cacacgccac gagtatgctg gttgaagccc atcgtccagt aggagatgac tttcttgttc
   133981 ggatcggcat acagctgcgc cagttgttct aactggtctt tcggcacgcc ggtcatttcg
   134041 gcagtttttt ccagcgtata ctcggcaacg aaggctttgt aatcttcaaa gctcatcggt
   134101 tcggaggcgt cagaacctgg attcttcgct gctttttcca gcggatgggt cggacgtaaa
   134161 ccgtagccga tgtccgtcgc ccctttgcgc aggttaacgt gcttgctgaa gaagtcctga
   134221 tttatcgcat tgttttgaat gatatagttg gcgatgtagt tcaggatcac caggtcagat
   134281 tgcggcgtaa agatgatgcc gttatccgcc agctcgaagc tacgatgctg gtaggtagaa
   134341 agcaccgcca cggtgacgtt ctggttagag agacgacggt tagtgatgcg tgaccagagg
   134401 atcgggtgca tctccgccat gttagcgccc cacagcacaa acgcgtcagc ctgctcgatg
   134461 tcgtcatagc agcccatcgg ctcatccata ccaaaggtac gcataaagcc aactactgcc
   134521 gacgccatac agtgacgtgc gttcgggtcg atgttgttcg aacggaagcc cgctttgaac
   134581 agcttggacg cggcataacc ttcccagata gtccactgac cagaaccgaa cataccgatc
   134641 gattccggtc ctttttcttt cagggcggtt ttgaatttct cttccatcac atcgaaggcc
   134701 tgatcccagg tgattggggt aaattcgcct tctttgtcat atttaccgtt tttcatacgc
   134761 agcagcggct gcgtcaaacg gtctttaccg tacatgatct tgggcaggaa atagccctta
   134821 atgcagttca ggccacggtt aaccggtgcg tccgggtcgc cctgacaggc caccacacgc
   134881 ccctgctgcg ttccgaccag aacgccgcaa ccagtaccgc agaaacggca cggcgcttta
   134941 tcccatttga tggcttcctg ctgaccaaca acggcgcggg caacgcccgg cacgctgaga
   135001 ccggcagccg ccgcagcggc cgcaacggcg ttagctttca taaagctacg acgactgagt
   135061 ttcatggtgt ttcctcacct tgctcttcct gctggtgata aaccagcgac accgccagca
   135121 cgccctctac gttgcgtact gactcaatgg tttggatcag cgtttcgctg tcttctgctt
   135181 ccaccaccac aatcaactga ccgctcggcg cgtcgctgac agcaacttca cagccgggaa
   135241 aggcgttcag ttgggtgctg atgtctgaaa ttcgttcgct tttggcctgc acgaccaggc
   135301 tgcaaacttg ccagttagtg tgcatggaga tactccgcag ttatggctga taccggacag
   135361 ctggctgcac atgctccaca tccgttgcaa agttggctat taagttgcgg ctggtagatc
   135421 ccggagagcg tcgggcgaaa gataattgcc attggctcac agctatcctg acagcggcgg
   135481 cattcaacag actgatacgc caggcacgcg tccccaatgg tgaactgcca atcccaggcc
   135541 ctggtgtggc gcggagaaaa tagcgattcg gggcaagcct gcgcgcaggc gtaacagaag
   135601 ctgcactcgt tatttttgaa attaacgctc ggatagccgc ccgcgccgcg ttgcagaatg
   135661 ttgttttcac aagcattaat acaggcgtcg cagcgggtgc aatgggtcag aaaatgagat
   135721 tcatcaccgg accagggcgg acggataccg ttactggctt tgcgccagcg accagtgagt
   135781 atgccccgac gggatgcatc aatcttcaca ttgaccttcc atcattaacg cgctctgaaa
   135841 attgagagcg accaaataaa ccgcataatt aataagccat ttttatagcc gctaagatat
   135901 taaaggatgt gtcaaagatg cataccccga tcggggtaaa acctgtagca ggatcaaaag
   135961 agtggcggga agcgtggcaa aaacgggctt ttgctcacat ttcaaatggt tataaatata
   136021 tttatatagc gattaattca ccagagatat ttctgctggt ttgctctctc attagaattt
   136081 aacactaaaa gagcaggtaa aattgtctga atgttcttta agttattcat aaagcaaatt
   136141 aataaatctg atgaatatgt taaccttcag cgacatcatc ggtgaaaacc tataaatgaa
   136201 gaaggaaagc aaaaaaatga agaccattct acctgcagta ttgtttgccg ctttcgctac
   136261 cacttccgcc tgggcggcag aaagcgtcca gccactggaa aaaatcgcgc cttatccaca
   136321 agctgaaaaa gggatgaagc gtcaggtgat tcagttaacc ccgcaagaag atgaatctac
   136381 cctgaaagta gaactgttaa tcggtcagac gctggaagtc gattgcaatt tgcatcgtct
   136441 cggcgggaag ctggaaaaca aaacgctgga aggctggggc tatgattatt atgtctttga
   136501 taaagttagc tcgccggttt ccacgatgat ggcctgcccg gatggcaaga aagagaagaa
   136561 atttgtcacc gcgtatctgg gcgatgctgg aatgctgcgt tacaacagca agctgccgat
   136621 cgtggtgtat acgccagaca atgtagatgt gaagtaccgc gtctggaagg cggaagagaa
   136681 aattgacaac gcggtagttc gctaaaatgc tgtgaagtgc ggcaccccgt aggccgaata
   136741 aggcggtcac gccgcatccg acatctaacg cccgagccgg tgcctgatgc gacgctggcg
   136801 cgtcttatca gcatacgcca catccggcat accatgccgg atgtggcaca tcattacaac
   136861 gcaatatccg ccacttcttt ttgaacgggt tgcggtttca actgcggttt tggcgtacta
   136921 tctgctgcct gcggcttgtc gtatttcagc cccagcactt cgctggtgta ctgcaactcg
   136981 cgttctgttg ccgctacatc accgttcagc ttgcgtccat aagacggaac gatcgctttc
   137041 aacgtagcct gccattgcgg gctggaaacg cgatcgccaa atactttttc cagcagatcc
   137101 aacataatcg gcgcggcggt tgacgcccct ggcgatgccc ccagcagcgc ggcaatggtc
   137161 ccttgctggt cactgaccac ttcagtaccc agacgcagta caccaccttt atcggcatca
   137221 cgcttgataa tctgcacgcg ctgccccgct tgccacaaac gccagtcctc ttttttcgct
   137281 tgcggatagt actctttcaa cgcttcaaaa cgatcctctt cactcaacat cacctgactc
   137341 accagatatt tcaccagatc gaaattatcc agcccgacgt gcatcatcgg catcacgtta
   137401 gaggtggtgg tggaactcat cagatcccac aatgaaccgt ttttgaggaa tttggttgag
   137461 aaggtggcaa atggcccaaa cagcactacg cgtttaccgt ccagaacgcg ggtatcgata
   137521 tgcggaaccg acatcggtgg tgcgccaacg gatgctttac cgtaaacctt cgccagatgg
   137581 tgattaacca cgtccgggtt ttccgaaaca aggaactgtc cgcccaccgg gaaaccggcg
   137641 tagtctttcg cttccggaat ccccgattcc tgtaatagct tcagcgccgc accgcccgcg
   137701 ccgataaaga caaatttggc acgaatgttc tgtgcagtgc cattttttag atcggcaacg
   137761 gtaacggtcc aggtgttatc gtcattacgc tttagggcgc ggacttcgct gctgagttgc
   137821 agcgagaagt tagatttctt ctgcaaggaa gcaattaact ggcgggtgat ctcgccgtag
   137881 ttcacatcgg taccaatttc cgtacgcgtg gctgccactt tctgttgcgg atcgcgccct
   137941 tccatcacta aaggtgccca ctctttgatc tgcgcgtgat cttcagagta acgcataccg
   138001 cgaaacagcg agctttgttg caacgcggcg taacgggcgc gcaggaaatt aacgttatcc
   138061 tcgccccaga caaagctcat atgcggaacg gtattgataa atgaacgcgg agtacgcagc
   138121 acgccgcgct cgacctggtg cgcccagaac tggcgggaaa tctgaaatgc ttcgttaatg
   138181 gcgactgctt tttcaatact gatgctgcca tcggcgtttt gcggggtgta gttcagttcc
   138241 atcagtgcag aatgcccggt tccggcgtta ttccagccgt tcgaactctc ctgcgcgaca
   138301 ccctccaggc gctccaccat ggtcatcgac cattcaggct ccagctcgcg taaataggtc
   138361 cccaacgtgg cgctcataat gccgccgcca atcaacagta catcagtttc ctgctcctcg
   138421 gacgctttcg cttttgccgc catcgaaacg gcattaagcc ccacggccat cgagaagagc
   138481 atggcagtca cttttttcat cttgttaatg ccttactttt agtcgcttta ttgcaggtga
   138541 gatttgcgcg gcatcaacgg taacacttaa gtaacaacat ttaaataatg tttataaatt
   138601 atattctaat tttagaaaca ttataatttc gttgattaat tatagggtta ttagaaatga
   138661 agggattttt agcatattga cctggcggca gcagtccgcc aggtcagcgt cgtaatatta
   138721 tgccgtccgg gcaacggcat cacgcgaagc agcatcgcgc tcttcgcccg tcagctcgct
   138781 aagttgcccg ttgcgcattt ccagcaggcg gtcggcgtgg ataaagtaat gatcatcatg
   138841 actgatggcg aaaatagttt tacccatctc ctgcatcagc ggcagcaaca cctgataaaa
   138901 ctcacgacgg aagtgtggat cctgatccgc cgcccattca tccagcagga taatatcgcg
   138961 ttcttctgcc agcgccagca acagcgccac gcgttttttc tgcccttttg ataacttcag
   139021 gttaacaata cgcccgttgc ttaactcaag cttatgagcc attttcagct gcgccagcca
   139081 cttctcaacc agttgcgggt tagcgggttt accctccggc cccagcagtt gatcaaacag
   139141 ccagacatcg gtaaacactg ccgaaaacag tttgcgataa tcttccggtt gttcgccgct
   139201 gacaggtttg ccatccagca agatttcgcc gctttgtggt tgatacaagc ccgtcaacaa
   139261 catcgccagc gtcgattttc cgctaccgtt gccgccaatc agaaacagca gctcgccacg
   139321 tttgatggtg agattaatcg gaccaacgga aaacgcgtta tcctgataag caaacgtcac
   139381 gttacgcagc tccagcgttt gccagttggg aaacgcctgc gggcgcggaa actctgcttt
   139441 gaaaggcgcg agcgcgaatt tgttcagctt gttaaacgcc acctgcgccg tcagcagcgt
   139501 cggcaatgcg ccaactgccg aaagcagcgg cgtacgcagg aataaaagcg tcaacgaata
   139561 ggtcgcggca acgttggtat cagcccaacc gagactgttc gccatccaga acaccaggcc
   139621 gattgcgccc aacatcatga tgtttgacca gttcacggcg ctaagatgga aggtgtctgc
   139681 gcggataata tggtggcgat actcttgcgc atcaggaatg tagaggttgt taaacacata
   139741 ctcggcgcgt tcccggttca gagtcagctc tttgcgccct tcgagtacag tttgaaaatc
   139801 cgtatacagc ctgtcttcgg tttcacgcag ggtcgccata tgtttgtaca cccgcgccac
   139861 cagtacaaaa ccaccccaga tggtgatcgc catccagata gccgttacca gcaacatttt
   139921 gcccgacagc atccacagat acgccgcgga accgatagtg agaatgatcc cctgcaccag
   139981 ttccggaaga cgcacaaaag caatggtgat attgcgcaca tcgctggtta atcccgccag
   140041 caacgaggcg ctaccgagtt gttcaatgcg ctcgacgttg gtatccagaa tccgcttgat
   140101 aaattcacta cgcagtcggt aaacgaagtg atgccccaaa gtggtgagcg ccagttgcga
   140161 tccgagagtg actgccatca acagcagcaa taatcccaga aactccggca ataccagcag
   140221 actggtatcc gccgtttcga taaggcgctg attgataaaa gcaattaagc caatgcctaa
   140281 tgccgcactg gcgaggctta gcgccatcac actgataaat ggccagcgat actgccgcca
   140341 gacaagtaca agaagttcca tgcagaaaac ccggacaatg aattacagcc cgcagtttaa
   140401 acatcttcgc gcgcacagca ataataattc ttatttttat tcttttttac ctgcctgacg
   140461 gaatgtcagg ttgtagcggc agtcggtggt gagtggatga aaccccgctt tcaacggttg
   140521 aataccgtga taaaacagcc gcgactcacc gccccacacc accacatcgc catgttccaa
   140581 caacaaacgt ttgagcggat cattacgttt caggccacca aattgaaaaa tcgcaggtaa
   140641 gcccagagaa acagaaacaa ttggcgcgcg cagatccggt tcgtctttat cctgatgcag
   140701 cgacagtttc gcgccaggag cgtagcggtt gataagacaa gcatctggct ggaaatctgg
   140761 atagcccgcc gccgtagccg cacgttgaca taaattatga aaactctgtg gcatggcggg
   140821 ccacggttta tttgtttgcg gatcaatggg cgaatagaga taaccttgcc gatggctcgt
   140881 ccagcccaga tgcccacagt tggtcatcgc caccgacatg gtatatcccc cgggggtgac
   140941 catctggcga aacggcgact ggctggcaac gtcattaata tcgcggatta gttgctccgc
   141001 agcattaaaa gcaaaacgcc gtaaaattac cgcaccagcc gccagtggct cttgccacgg
   141061 ttcagcatcg gcaaacagat ccaacattac ctctcctcat tttcagcttc gcggcgcagc
   141121 agttgcgctt tacgcgacac gccccagcgg taaccggaaa gtgtgccatc accacggacc
   141181 acccgatgac agggtattat gatagccagc ttgttggcgg cacaggcgct ggcaacggcc
   141241 cgtaccgctt tcggtttgcc gatggcgtta gccagttgct gataactgac ggtttcaccg
   141301 caaggtatcg tgcgcagtgc ctgccagact tgttgctgaa aagcagtgcc gcgaatgtcc
   141361 agcggtaacg tcagcggcgt atcgcgttga ttgaggctgg cgatcacttc acgcacatgt
   141421 tgctgaaaca tcagatcggc aggcgcgttg tcggcagcgg gaaacatctg ctgcaactcg
   141481 ctgattagtg tcgcgtcatc atcgcccagc aatatcgcgc aaatcccccg ctcgctttct
   141541 gccaccaggc tacgacccag ctcacaatca gccagcgcgt aacgcaccgc cagattttcg
   141601 ccaccgtgac ggaattgttt agccgtcatg cccagcgttt catcggcttt gcggtagtaa
   141661 ctgctgctgt cggggaatcc ggcgttaaga atagacgtcg tcacgctctc ccctttcgcc
   141721 agcgattcgc gcaaacggcg agcgcgccag gcctgttgcc aggctttagg cgtcattccg
   141781 gtagtcgctt taaacaaccg atgtagatga aatggactca tcaccacctg gtcggctaag
   141841 gcttccagcg ttacaggcgt ttcctgttcc agcagtcgac acgcgtgggt gattttatcc
   141901 aaccgatgtt gctgggcatt ggctttttct ggctgacaac gtttgcaggg gcgaaagcca
   141961 gcggcgagtg cctcgctggc atttgcgtag aaggagacgt tttcccgcaa agcatgtctg
   142021 gcgcggcaag acggacggca aaagatgcct gtggtacgca cggcgaaaac gaattcgccg
   142081 tcggcattcg ggtcgcgggc taagacagat tgccagcatt gatcgtcagt taagcatgtg
   142141 gcttttttca taatcagctc cctggttaag gatagccttt agtctgcccg gtcaccatca
   142201 cgcaaaaacc aacaatcttg cgctttaatt tttttcgctg ataaggaagc ttttaaactg
   142261 cggcgacatc caggttttaa agctatcacc ttctttggtg atcatataga ccgccagccc
   142321 ttcccggcga acaacctctt tggctttctc cggcccgagt accattaagc cagtatccca
   142381 ggcatcggct tccagcgccg tcggggcaat caccgtcacg gataccagat tgtgttcgat
   142441 aggacgcccg gtttgcggat cgataacatg agaaagacgt ttgccgtcca gttcgtaata
   142501 gttacggtag ctgccagagg tgctaatgcc atgaccgttg atatccacca cggcctgaac
   142561 cgcgttttct ttatcggttg gtttttgaat cgctacccgc cacggctggc cttcaccgtt
   142621 cataccacgg ctatccagag caccaccaac tgacaccaga taacgtgaaa taccttcctg
   142681 ctccatcaag cgtgccaggt gatccgccgc ataaccttca ccgacggtgg agagatcgac
   142741 atataaatcc ggcaggtctt tttgcagata ttgctgatgc gactgattga tgaccgtcag
   142801 gtgctgtaag ccggttttgg ctttcatcgc atcgatctgt tcctggctcg gaatttgaac
   142861 cggctgttgt tccgggccaa agccccacag attcaccagc ggcccgacgg ttatatccat
   142921 cgcaccatcg gtccttgcgc caatgcgcag cgaggtggtg acgatatcgg ccatcgcttc
   142981 acttaccggc cacggcgaca aactttgcga gtcgttaaag cgcatcagcg tggaatcttt
   143041 tttataggtc gaaagcagct gatcgtcggc gtccagctgg gtctgaatct tttctttaag
   143101 ttcggcactg cgtttggcat caatgcccgg gatgctggca cgccagaagg tacccatggt
   143161 tttgccttca agaacggtaa cttcagtagc gtgggttttg gcgggttgtg gtttttgatc
   143221 gcaaccaaca aagaagagcg cggcagccag cagtgccacg cgggtaaagc ttatttccat
   143281 acgtgattat cctcatgcga acggtcgcaa gagtacacca aaaaaatgag tttgtacgct
   143341 gaaaacaatg aaaaaagggc ccgcaggccc tttgttcgat atcaatcgag attagaactg
   143401 gtaaaccaga cccagagcta cgatgttatc agtgttgatg ccagcgtcac gagtgaactg
   143461 gttgtcgtcc agcaggttga ttttgtagtc aacgtaggtg gacatgtttt tgttgaagta
   143521 gtaggtagca ccaacatcaa catatttcag gatatcttcg tcgtcgtagt tacgaccagc
   143581 gatggtaccc aggtttttac ctttagactg caggtatgct acagacggac gcagaccgaa
   143641 gtcgaactgg tactgagcaa cagcttcaaa gttctgtgct ttgttcgccc aacccaggga
   143701 acctacgcga gttgcgttat aggtctgggt gtactgagca gccaggtaga tgttgttagc
   143761 gtcgtatttc agaccaccgg tgtaggtttc agcacggtcg ccgttaccga tgtacagcgg
   143821 gctgttctga tcatcagtac gtttggagct ggagatcgca ccaccgatac cgaagccttc
   143881 gtaatcataa gtgatagatc cgccaacgcc gtcgccgttc tgacgcagag caccacgacc
   143941 gttgttggtc atgccttcgc cgcttacgct accgttttta ccctggtact gaacagcaaa
   144001 gttcaggccg tcaaccagac cgaagaagtc agtgttacgg taggtcgcga agccgttacc
   144061 acgctgctgc atgaagttgt cagaaccgta ggtgtcacca ccgaattctg gcagtacgtc
   144121 ggtccaggaa gttacgtcgt aaacaacgcc gtagttacga ccgtagtcga aagaacctac
   144181 atcctggaat ttcagacctg cgaatgccac acgggtccag gagttgtttt cgttttcagc
   144241 gctgttgccc tgaatctgat attcccactg gccgtaaccg gtcagctggt cagtaacctg
   144301 agtttcacct ttgaagccaa gacgcatgta ggtctggtcg ccatctacat ctttgttgtc
   144361 agagaaatag tgcaggccgt ctactttacc gtacagatct aatttgttgc cgtctttgtt
   144421 gtaaacttca gcagcgtttg ctgcgcctgc taccagcaga gctgggacca ggagggacag
   144481 tactttaact ttcatgttat taaccctctg ttatatgcct ttatttgctt ttttatgcca
   144541 ctgcatactg attaaccctc attaatcagt cggcaagtcc attctcccca aaaatgcaga
   144601 ataatccaac acgaatatga tactaaaact tttaagatgt ttcatttatc gctatagatg
   144661 tttcaaaatg taaatgcaag ggaacttttt aagattattg cgg
//
LOCUS       DAZUDJ010000002       130722 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.002, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000002 DAZUDJ010000000
VERSION     DAZUDJ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 130722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 130722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..130722
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.002"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(28..738)
                     /gene="nlpE"
                     /locus_tag="ACHY1N_000132"
                     /gene_synonym="cutF"
     CDS             complement(28..738)
                     /gene="nlpE"
                     /locus_tag="ACHY1N_000132"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706138.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HFS4042493.1"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAQSSLPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERSYLAARGHSEKPVLLSVEGHFTLEANPDTGAPTKVLA
                     PDTAGKFYPNKDCSSLGQ"
     gene            complement(752..1174)
                     /gene="arfB"
                     /locus_tag="ACHY1N_000133"
     CDS             complement(752..1174)
                     /gene="arfB"
                     /locus_tag="ACHY1N_000133"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome rescue aminoacyl-tRNA
                     hydrolase ArfB"
                     /protein_id="HFS4042494.1"
                     /translation="MIVISRHVAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAVIKDLTTEQ
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     gene            complement(1171..1716)
                     /gene="yaeQ"
                     /locus_tag="ACHY1N_000134"
     CDS             complement(1171..1716)
                     /gene="yaeQ"
                     /locus_tag="ACHY1N_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HFS4042495.1"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFTYNSRAAQIWWQQNQSKCVQFANLSVWYLDDEQLAKVSVFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTAWQQPS"
     gene            1882..2082
                     /gene="yaeP"
                     /locus_tag="ACHY1N_000135"
     CDS             1882..2082
                     /gene="yaeP"
                     /locus_tag="ACHY1N_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HFS4042496.1"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     gene            2069..2329
                     /gene="rof"
                     /locus_tag="ACHY1N_000136"
     CDS             2069..2329
                     /gene="rof"
                     /locus_tag="ACHY1N_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HFS4042497.1"
                     /translation="MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
                     LVSRKNVEYLVVEAAGETRELRLDKITSFSHPEIGTVVVSES"
     gene            complement(2378..3676)
                     /gene="tilS"
                     /locus_tag="ACHY1N_000137"
     CDS             complement(2378..3676)
                     /gene="tilS"
                     /locus_tag="ACHY1N_000137"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFS4042498.1"
                     /translation="MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGVTL
                     RAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
                     GELEQWALAHGLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDLAHCQTSQGTLQIAPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSETIVPWQTWLQPLELPA
                     GLGSVQLTAGGDIRPPRADEAVSVRFKAAGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAEGENGVSFVWQKTLS"
     gene            complement(3741..4130)
                     /gene="yaeR"
                     /locus_tag="ACHY1N_000138"
     CDS             complement(3741..4130)
                     /gene="yaeR"
                     /locus_tag="ACHY1N_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308216.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4042499.1"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCEA
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     gene            complement(4187..6328)
                     /gene="ldcC"
                     /locus_tag="ACHY1N_000139"
     CDS             complement(4187..6328)
                     /gene="ldcC"
                     /locus_tag="ACHY1N_000139"
                     /EC_number="4.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HFS4042500.1"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWF
                     FEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWF
                     FDIWQPPQVDEAECWPVAPGEQWHGFNDADADHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSV
                     VQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     gene            complement(6427..7386)
                     /gene="accA"
                     /locus_tag="ACHY1N_000140"
     CDS             complement(6427..7386)
                     /gene="accA"
                     /locus_tag="ACHY1N_000140"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFS4042501.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLSVPTICTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     gene            complement(7399..10881)
                     /gene="dnaE"
                     /locus_tag="ACHY1N_000141"
     CDS             complement(7399..10881)
                     /gene="dnaE"
                     /locus_tag="ACHY1N_000141"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFS4042502.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLETELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            complement(10918..11514)
                     /gene="rnhB"
                     /locus_tag="ACHY1N_000142"
     CDS             complement(10918..11514)
                     /gene="rnhB"
                     /locus_tag="ACHY1N_000142"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFS4042503.1"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     gene            complement(11511..12659)
                     /gene="lpxB"
                     /locus_tag="ACHY1N_000143"
     CDS             complement(11511..12659)
                     /gene="lpxB"
                     /locus_tag="ACHY1N_000143"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008915 - lipid-A-disaccharide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HFS4042504.1"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDIFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKQLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     gene            complement(12659..13447)
                     /gene="lpxA"
                     /locus_tag="ACHY1N_000144"
     CDS             complement(12659..13447)
                     /gene="lpxA"
                     /locus_tag="ACHY1N_000144"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008780 -
                     acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine
                     O-acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HFS4042505.1"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     gene            complement(13451..13906)
                     /gene="fabZ"
                     /locus_tag="ACHY1N_000145"
     CDS             complement(13451..13906)
                     /gene="fabZ"
                     /locus_tag="ACHY1N_000145"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFS4042506.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            complement(14011..15036)
                     /gene="lpxD"
                     /locus_tag="ACHY1N_000146"
     CDS             complement(14011..15036)
                     /gene="lpxD"
                     /locus_tag="ACHY1N_000146"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HFS4042507.1"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     gene            complement(15040..15525)
                     /gene="skp"
                     /locus_tag="ACHY1N_000147"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             complement(15040..15525)
                     /gene="skp"
                     /locus_tag="ACHY1N_000147"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HFS4042508.1"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     gene            complement(15647..18079)
                     /gene="bamA"
                     /locus_tag="ACHY1N_000148"
     CDS             complement(15647..18079)
                     /gene="bamA"
                     /locus_tag="ACHY1N_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_process: GO:0071709 - membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HFS4042509.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     gene            complement(18109..19461)
                     /gene="rseP"
                     /locus_tag="ACHY1N_000149"
     CDS             complement(18109..19461)
                     /gene="rseP"
                     /locus_tag="ACHY1N_000149"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HFS4042510.1"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            complement(19473..20330)
                     /gene="cdsA"
                     /locus_tag="ACHY1N_000150"
     CDS             complement(19473..20330)
                     /gene="cdsA"
                     /locus_tag="ACHY1N_000150"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414717.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFS4042511.1"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRLIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            complement(20343..21101)
                     /gene="ispU"
                     /locus_tag="ACHY1N_000151"
                     /gene_synonym="uppS"
     CDS             complement(20343..21101)
                     /gene="ispU"
                     /locus_tag="ACHY1N_000151"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002094 - polyprenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008834 -
                     di-trans,poly-cis-undecaprenyl-diphosphate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0043164 - Gram-negative-bacterium-type cell
                     wall biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HFS4042512.1"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     gene            complement(21290..22486)
                     /gene="ispC"
                     /locus_tag="ACHY1N_000152"
     CDS             complement(21290..22486)
                     /gene="ispC"
                     /locus_tag="ACHY1N_000152"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HFS4042513.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     gene            complement(22578..23135)
                     /gene="frr"
                     /locus_tag="ACHY1N_000153"
     CDS             complement(22578..23135)
                     /gene="frr"
                     /locus_tag="ACHY1N_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFS4042514.1"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     gene            complement(23427..24152)
                     /gene="pyrH"
                     /locus_tag="ACHY1N_000154"
     CDS             complement(23427..24152)
                     /gene="pyrH"
                     /locus_tag="ACHY1N_000154"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFS4042515.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            complement(24299..25150)
                     /gene="tsf"
                     /locus_tag="ACHY1N_000155"
     CDS             complement(24299..25150)
                     /gene="tsf"
                     /locus_tag="ACHY1N_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFS4042516.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            complement(25408..26133)
                     /gene="rpsB"
                     /locus_tag="ACHY1N_000156"
     CDS             complement(25408..26133)
                     /gene="rpsB"
                     /locus_tag="ACHY1N_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFS4042517.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            26501..27295
                     /gene="map"
                     /locus_tag="ACHY1N_000157"
     CDS             26501..27295
                     /gene="map"
                     /locus_tag="ACHY1N_000157"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFS4042518.1"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     gene            27357..30029
                     /gene="glnD"
                     /locus_tag="ACHY1N_000158"
     CDS             27357..30029
                     /gene="glnD"
                     /locus_tag="ACHY1N_000158"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HFS4042519.1"
                     /translation="MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     gene            30060..30884
                     /gene="dapD"
                     /locus_tag="ACHY1N_000159"
     CDS             30060..30884
                     /gene="dapD"
                     /locus_tag="ACHY1N_000159"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008666 -
                     2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HFS4042520.1"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            31196..31582
                     /gene="yaeH"
                     /locus_tag="ACHY1N_000160"
     CDS             31196..31582
                     /gene="yaeH"
                     /locus_tag="ACHY1N_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HFS4042521.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     gene            complement(31671..32828)
                     /gene="cdaR"
                     /locus_tag="ACHY1N_000161"
     CDS             complement(31671..32828)
                     /gene="cdaR"
                     /locus_tag="ACHY1N_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CdaR"
                     /protein_id="HFS4042522.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTELDLGNFDDRLLLYVALQLDEER"
     gene            complement(32983..34407)
                     /gene="degP"
                     /locus_tag="ACHY1N_000162"
     CDS             complement(32983..34407)
                     /gene="degP"
                     /locus_tag="ACHY1N_000162"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HFS4042523.1"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSS
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSSIYLLMQ"
     gene            complement(34537..36054)
                     /gene="dgt"
                     /locus_tag="ACHY1N_000163"
     CDS             complement(34537..36054)
                     /gene="dgt"
                     /locus_tag="ACHY1N_000163"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008832 - dGTPase activity [Evidence IEA];
                     GO_process: GO:0006203 - dGTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HFS4042524.1"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            36138..36836
                     /gene="mtnN"
                     /locus_tag="ACHY1N_000164"
     CDS             36138..36836
                     /gene="mtnN"
                     /locus_tag="ACHY1N_000164"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFS4042525.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     gene            36829..37629
                     /gene="btuF"
                     /locus_tag="ACHY1N_000165"
     CDS             36829..37629
                     /gene="btuF"
                     /locus_tag="ACHY1N_000165"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HFS4042526.1"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     gene            37667..38290
                     /gene="yadS"
                     /locus_tag="ACHY1N_000166"
     CDS             37667..38290
                     /gene="yadS"
                     /locus_tag="ACHY1N_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HFS4042527.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     gene            complement(38337..38681)
                     /gene="erpA"
                     /locus_tag="ACHY1N_000167"
     CDS             complement(38337..38681)
                     /gene="erpA"
                     /locus_tag="ACHY1N_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HFS4042528.1"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(38674..38739)
                     /gene="yadW"
                     /locus_tag="ACHY1N_000168"
     CDS             complement(38674..38739)
                     /gene="yadW"
                     /locus_tag="ACHY1N_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small protein YadW"
                     /protein_id="HFS4042529.1"
                     /translation="MAIIIGLEFAQLPMSFGAKYE"
     gene            complement(38763..40184)
                     /gene="clcA"
                     /locus_tag="ACHY1N_000169"
     CDS             complement(38763..40184)
                     /gene="clcA"
                     /locus_tag="ACHY1N_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HFS4042530.1"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     gene            complement(40196..40243)
                     /gene="yadX"
                     /locus_tag="ACHY1N_000170"
     CDS             complement(40196..40243)
                     /gene="yadX"
                     /locus_tag="ACHY1N_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YadX"
                     /protein_id="HFS4042531.1"
                     /translation="MERASKMPSSYLYDQ"
     gene            40409..41689
                     /gene="hemL"
                     /locus_tag="ACHY1N_000171"
     CDS             40409..41689
                     /gene="hemL"
                     /locus_tag="ACHY1N_000171"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HFS4042532.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVEPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTSRLAEG
                     LLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     gene            complement(41724..43706)
                     /gene="fhuB"
                     /locus_tag="ACHY1N_000172"
     CDS             complement(41724..43706)
                     /gene="fhuB"
                     /locus_tag="ACHY1N_000172"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HFS4042533.1"
                     /translation="MSKRIALFPALLLALLVIVATALTWMNFSQALPRSQWAQAAWSP
                     DINVIEQMIFHYSLLPRLAISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVATERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLDDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPAGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     gene            complement(43703..44593)
                     /gene="fhuD"
                     /locus_tag="ACHY1N_000173"
     CDS             complement(43703..44593)
                     /gene="fhuD"
                     /locus_tag="ACHY1N_000173"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HFS4042534.1"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYED
                     FIRSMKPRFVKRGERPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRVLDNAIGGKA"
     gene            complement(44593..45390)
                     /gene="fhuC"
                     /locus_tag="ACHY1N_000174"
     CDS             complement(44593..45390)
                     /gene="fhuC"
                     /locus_tag="ACHY1N_000174"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HFS4042535.1"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIVQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     gene            complement(45441..47684)
                     /gene="fhuA"
                     /locus_tag="ACHY1N_000175"
     CDS             complement(45441..47684)
                     /gene="fhuA"
                     /locus_tag="ACHY1N_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015344 - siderophore uptake transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0038023 - signaling receptor activity
                     [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
                     /protein_id="HFS4042536.1"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLD
                     DDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLR
                     FAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDT
                     QLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLNLYNPVNTDFDFNAKDP
                     ANSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQ
                     FTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRP
                     IVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYT
                     DAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS
                     FKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVV
                     ATATFRF"
     gene            complement(47904..50438)
                     /gene="mrcB"
                     /locus_tag="ACHY1N_000176"
     CDS             complement(47904..50438)
                     /gene="mrcB"
                     /locus_tag="ACHY1N_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009274 - peptidoglycan-based cell wall
                     [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HFS4042537.1"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRVLPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
     gene            complement(50634..53063)
                     /gene="hrpB"
                     /locus_tag="ACHY1N_000177"
     CDS             complement(50634..53063)
                     /gene="hrpB"
                     /locus_tag="ACHY1N_000177"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HFS4042538.1"
                     /translation="MSSLPVAAVLSELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVVISEGRSFPVERHYLPLPAHQRFDEAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPGISLH
                     LIAKEQAERAAAQSEPEILQSDLSGFLMELLQWGCSDPAQMSWLDQPPTVNLLAAKRL
                     LQMLGALEGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDG
                     RYQLANGMGAMLDANDALSRHEWLIAPLLLQGSASPDARILLALPVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIREKGLSVL
                     NWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLATLETWLLPHMTGVHSLRGLKSLD
                     IYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATN
                     PTIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     gene            53137..53667
                     /gene="thpR"
                     /locus_tag="ACHY1N_000178"
     CDS             53137..53667
                     /gene="thpR"
                     /locus_tag="ACHY1N_000178"
                     /EC_number="3.1.4.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004113 - 2',3'-cyclic-nucleotide
                     3'-phosphodiesterase activity [Evidence IEA];
                     GO_function: GO:0008664 - RNA 2',3'-cyclic
                     3'-phosphodiesterase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HFS4042539.1"
                     /translation="MSEPQRLFFAIDLPAEIREQIIHWRATHFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     gene            53682..54386
                     /gene="sfsA"
                     /locus_tag="ACHY1N_000179"
     CDS             53682..54386
                     /gene="sfsA"
                     /locus_tag="ACHY1N_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFS4042540.1"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     ISAEGMALKKSLPVTL"
     gene            54564..55019
                     /gene="dksA"
                     /locus_tag="ACHY1N_000180"
     CDS             54564..55019
                     /gene="dksA"
                     /locus_tag="ACHY1N_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HFS4042541.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            55086..55982
                     /gene="gluQRS"
                     /locus_tag="ACHY1N_000181"
     CDS             55086..55982
                     /gene="gluQRS"
                     /locus_tag="ACHY1N_000181"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001432381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HFS4042542.1"
                     /translation="MTDTQYIGRFAPSPSGELHFGSLIAALGSYLQARARQGRWLVRI
                     EDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHDAYREALAWLHEQGLSYYCT
                     CTRARIQSIGGIYDGHCRVLHHGPDNAAVRIRQQHPVTQFTDQLRGIIHADEKLARED
                     FIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQISLYQLFGWKVPDYIHL
                     PLALNPQGAKLSKQNHAPALPKGDPRPVLIAALQFLGQQAEAHWQDFSVEQILQSAVK
                     NWRLTAVPESAIVNSTFSNASC"
     gene            56042..57439
                     /gene="pcnB"
                     /locus_tag="ACHY1N_000182"
     CDS             56042..57439
                     /gene="pcnB"
                     /locus_tag="ACHY1N_000182"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414685.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:1990817 - poly(A) RNA polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HFS4042543.1"
                     /translation="MFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQHAISRKDI
                     SENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLFRNCRLV
                     GRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGSIEEDAQR
                     RDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLRAVRFAAK
                     LGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLF
                     PTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLETAQKIA
                     QESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLL
                     EHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDEEPSPRRR
                     TRRPRKRAPRREGTA"
     gene            57436..57915
                     /gene="folK"
                     /locus_tag="ACHY1N_000183"
     CDS             57436..57915
                     /gene="folK"
                     /locus_tag="ACHY1N_000183"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HFS4042544.1"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILAVSSFYRTP
                     PLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELAFPDGETLREVLHTRAFDKLSKW"
     gene            58285..58869
                     /gene="yadN"
                     /locus_tag="ACHY1N_000184"
     CDS             58285..58869
                     /gene="yadN"
                     /locus_tag="ACHY1N_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4042545.1"
                     /translation="MSKKLGFALSGLMLAMVAGTASADMDGGQLNISGLVVDNTCETR
                     VDGGNKDGLILLQTATVGEIDAGVLNDTVGAKAKPFSITVDCSKANPNPGSTAKMTFG
                     SVFFGNSKGTLNNDMSINNPSDGVNIALHNIDGSTIKQVQINNPGDVYTKALDATTKS
                     AVYDFKASYVRAVADQTATAGYVKTNTAYTITYQ"
     gene            58974..59714
                     /gene="yadV"
                     /locus_tag="ACHY1N_000185"
     CDS             58974..59714
                     /gene="yadV"
                     /locus_tag="ACHY1N_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HFS4042546.1"
                     /translation="MFFNTKHTTALCFVTCMAFSSSSIADIVISGTRVIYKSDQKSVN
                     VRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTAST
                     SLPKDRESVFWFNVLEVPPKPDAEKVANQSLLQLAFRTRIKLFYRPDGLKGNPSEAPL
                     ALKWFWSGSEGKASLRVTNPTPYYVSFSSGDLEASGKRYPIDVKMIAPFSDEVMKVTG
                     LNGKASSAKVHFYAINDFGGAIEGNASL"
     gene            59749..62349
                     /gene="htrE"
                     /locus_tag="ACHY1N_000186"
     CDS             59749..62349
                     /gene="htrE"
                     /locus_tag="ACHY1N_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Yad fimbria usher protein HtrE"
                     /protein_id="HFS4042547.1"
                     /translation="MTIKPTKNYHNHLTRIATFCALLYCNSAFCAEPVEYDHTFLMGQ
                     NASNIDLSRYSEGNPAIPGMYDVSVYVNDQPIINQSITFIEIEGKKNAQACITLKNLL
                     QFHINSPDINNEKAVLLARDETLGNCLNLTEIIPQASVRYDVNEQRLDIDVPQAWVMK
                     NYQNYVDPSLWENGINAAMLSYNLNGYHSETPGRRNDSIYAAFNGGMNLGAWRLRASG
                     NYNWMTDSGSNYDFKNRYIQRDIASLRSQLILGESYTTGETFDSVSIRGIRLYSDSRM
                     LPPTLASFAPIIHGVANTNAKVTITQGGYKIYETTVPPGAFVIDDLSPSGYGSDLIVT
                     VEESDGSKRTFSQPFSSVVQMLRPGVGRWDISGGQVLKDDIQDEPNLFQASYYYGLNN
                     YLTGYTGIQITDNNYTAGLLGLGLNTSVGAFSFDVTHSNVRIPDDKTYQGQSYRVSWN
                     KLFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVKHPEQDLEPKSMRNYSRMKNQVT
                     VSINQPLKFEKKDYGSFYLSGSWSDYWASGQNRSNYSIGYSNSASWGSYSVSAQRSWN
                     EDGDTDDSVYLSFTIPIEKLLGTEQRTSGFQSIDTQMSSDFKGNNQLNVSSSGYSDNA
                     RVSYSVNTGYTMNKASKDLSYVGGYASYESPWGSLAGSVSANSDNSRQVSLSTDGGFV
                     LHSGGLTFSNDSFSDSDTLAVVQAPGAQGARINYGNSTIDRWGYGVTSALSPYHENRI
                     ALDINDLENDVELKSTSAVAVPRQGSVVFADFETVQGQSAIMNITRSDGKNIPFAADI
                     YDEQGNVIGNVGQGGQAFVRGIEQQGNISIKWLEESKPVSCLAHYQQSSEAEKIAQSI
                     ILNGIRCQIQ"
     gene            62366..62935
                     /gene="yadM"
                     /locus_tag="ACHY1N_000187"
     CDS             62366..62935
                     /gene="yadM"
                     /locus_tag="ACHY1N_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414680.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4042548.1"
                     /translation="MIKITPHKIAILMGILLSPSVFATDINVEFTATVKATTCNITLT
                     GNNVTNDGNNNYTLRIPKMGLDKIANKTTESQADFKLVASGCSSGISWIDTTLTGNAS
                     SSSPKLIIPQSGDSSSTTSNIGMGFKKRTTDDATFLKPNSAEKIRWSTDEMQPDKGLE
                     MTVALRETDAGQGVPGNFRALATFNFIYQ"
     gene            62950..63552
                     /gene="yadL"
                     /locus_tag="ACHY1N_000188"
     CDS             62950..63552
                     /gene="yadL"
                     /locus_tag="ACHY1N_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein YadL"
                     /protein_id="HFS4042549.1"
                     /translation="MTFKNLRYGLSSSVVLAASLFSVPSYAATDSIGLTVITTVEIGT
                     CTATLVNDSDQDISVVDFGDVYISEINAKTKVKTFKLKFKDCAGIPNKKAQIKLTKRA
                     TCEGTANDGAGFANGSTAADKASAVAVEVWSTETPATGSATQFSCVTPASQEVTISNA
                     ANAVVYYPMSARLVVEKNKTVSNVTAGKFSAPATFTVTYN"
     gene            63579..64175
                     /locus_tag="ACHY1N_000189"
     CDS             63579..64175
                     /locus_tag="ACHY1N_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein"
                     /protein_id="HFS4042550.1"
                     /translation="MHPTQRKLMKRIILFLSLQFPITYPAIAGQDIDLVANVKNSTCK
                     SGISNQGNIDLGVVGVGYFSDNVTPESYQPGGKEFTVTVSDCALQGTGDVLNQLHIDF
                     RALSGVMAAGSRQIFANEVATGAKNVGVVLFSIQDPTNIFNVISSAGNSRSVYPVMTS
                     ALHNSSWKFYARMQKIDPALDVISGQVMSHILVDVYYE"
     gene            64159..65502
                     /locus_tag="ACHY1N_000190"
     CDS             64159..65502
                     /locus_tag="ACHY1N_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001462196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like adhesin"
                     /protein_id="HFS4042551.1"
                     /translation="MCTTNNRSKQITATVTAVDGGVIMKKFFRHFLFLILCLSCYTAS
                     AGTDDNVGYIVGNSYGVGPSDQKWRETGPNGDATVIFRYATSTNNLVFYKPTQLGPTG
                     VKLQWSQLDTASGGGFLYCNRSDSTSGSAMRIENAMVDSGKMYGSHKLFNTSVPGLYY
                     TLLISNMWSAYGTVTNVSSPGIYIGDSAEQYFSWYNPSEDVLYWSCNNANSTRKYWAV
                     GGIYQTLTIEFYTDTNFDPTVTQQIKLSSSSNYLYSFKAYGAGQGINEHSYFIKIDFD
                     LLNVKLTNPTCFTAMLSGTSVTGSTVKMGEYSAEQIRNGATPVPFDISLQNCVRVTNI
                     ETKLVSTKVGTENGQLLGNTLTGNDAAKGVGVLIEGLATSKNPLMTLKPNDSNSVYKD
                     YDPRGKDDTTGGVYPDQDTGITYPLHFQATLQQDGTIPIEAGEFKATSTFQVTYP"
     gene            65615..66409
                     /gene="panB"
                     /locus_tag="ACHY1N_000191"
     CDS             65615..66409
                     /gene="panB"
                     /locus_tag="ACHY1N_000191"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HFS4042552.1"
                     /translation="MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFADEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVEDIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAG
                     DQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     gene            66421..67272
                     /gene="panC"
                     /locus_tag="ACHY1N_000192"
     CDS             66421..67272
                     /gene="panC"
                     /locus_tag="ACHY1N_000192"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HFS4042553.1"
                     /translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLID
                     NKMVELA"
     gene            complement(67346..68248)
                     /gene="rpnC"
                     /locus_tag="ACHY1N_000193"
     CDS             complement(67346..68248)
                     /gene="rpnC"
                     /locus_tag="ACHY1N_000193"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnC"
                     /protein_id="HFS4042554.1"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLEIHLPVELRELCDLNTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGNPGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDIFYSPELARRVYNSPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGESMMTLAQWFEEKGIEKGIQQGRQEERQEFALRLLSKG
                     MSREDVAEMTNLSLAEIDKVINLI"
     gene            68522..68902
                     /gene="panD"
                     /locus_tag="ACHY1N_000194"
     CDS             68522..68902
                     /gene="panD"
                     /locus_tag="ACHY1N_000194"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HFS4042555.1"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     gene            complement(68906..70135)
                     /gene="yadE"
                     /locus_tag="ACHY1N_000195"
     CDS             complement(68906..70135)
                     /gene="yadE"
                     /locus_tag="ACHY1N_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFS4042556.1"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAIWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYAFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLITWKDTPVYNAPSAGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLPVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMAQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFVVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRVDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVWYLSYPFGGFNDKAVKAANDAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     gene            complement(70199..70639)
                     /gene="yadI"
                     /locus_tag="ACHY1N_000196"
     CDS             complement(70199..70639)
                     /gene="yadI"
                     /locus_tag="ACHY1N_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4042557.1"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSEFRERIVELGGPEVSSLWHQQQKNPPFVLKHNLYEY"
     gene            complement(70744..71514)
                     /gene="yadH"
                     /locus_tag="ACHY1N_000197"
     CDS             complement(70744..71514)
                     /gene="yadH"
                     /locus_tag="ACHY1N_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4042558.1"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     gene            complement(71511..72437)
                     /gene="yadG"
                     /locus_tag="ACHY1N_000198"
     CDS             complement(71511..72437)
                     /gene="yadG"
                     /locus_tag="ACHY1N_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4042559.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRA"
     gene            72546..73208
                     /gene="can"
                     /locus_tag="ACHY1N_000199"
     CDS             72546..73208
                     /gene="can"
                     /locus_tag="ACHY1N_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HFS4042560.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     gene            complement(73249..73785)
                     /gene="hpt"
                     /locus_tag="ACHY1N_000200"
     CDS             complement(73249..73785)
                     /gene="hpt"
                     /locus_tag="ACHY1N_000200"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFS4042561.1"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     gene            73991..76381
                     /gene="gcd"
                     /locus_tag="ACHY1N_000201"
     CDS             73991..76381
                     /gene="gcd"
                     /locus_tag="ACHY1N_000201"
                     /EC_number="1.1.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein glucose dehydrogenase"
                     /protein_id="HFS4042562.1"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSANATPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPKKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     gene            complement(76428..77978)
                     /gene="cueO"
                     /locus_tag="ACHY1N_000202"
     CDS             complement(76428..77978)
                     /gene="cueO"
                     /locus_tag="ACHY1N_000202"
                     /EC_number="1.16.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HFS4042563.1"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGEKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFNADGQIDYQLDVMTAAVGWFGDTLLTNG
                     AIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTL
                     SSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN
                     MNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHNAPKEHAYMAHCHLLEHEDT
                     GMMLGFTV"
     gene            78144..78491
                     /gene="yacC"
                     /locus_tag="ACHY1N_000203"
     CDS             78144..78491
                     /gene="yacC"
                     /locus_tag="ACHY1N_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414664.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HFS4042564.1"
                     /translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            78597..79463
                     /gene="speE"
                     /locus_tag="ACHY1N_000204"
     CDS             78597..79463
                     /gene="speE"
                     /locus_tag="ACHY1N_000204"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HFS4042565.1"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALP
                     QYLQDALASQPS"
     gene            79479..80273
                     /gene="speD"
                     /locus_tag="ACHY1N_000205"
     CDS             79479..80273
                     /gene="speD"
                     /locus_tag="ACHY1N_000205"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004014 - adenosylmethionine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HFS4042566.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     gene            complement(80311..80673)
                     /gene="yacL"
                     /locus_tag="ACHY1N_000206"
     CDS             complement(80311..80673)
                     /gene="yacL"
                     /locus_tag="ACHY1N_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414661.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YacL"
                     /protein_id="HFS4042567.1"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVIVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     gene            complement(80849..83446)
                     /gene="acnB"
                     /locus_tag="ACHY1N_000207"
     CDS             complement(80849..83446)
                     /gene="acnB"
                     /locus_tag="ACHY1N_000207"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.99"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HFS4042568.1"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVTDGATVVSTSTRNFPNRLG
                     TGANVFLASAELAVVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFNQLSQYTEKA
                     DGVIFQTAV"
     gene            83801..85558
                     /gene="yacH"
                     /locus_tag="ACHY1N_000208"
     CDS             83801..85558
                     /gene="yacH"
                     /locus_tag="ACHY1N_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HFS4042569.1"
                     /translation="MKMTLPFKPHVLALICSAGLCAASTGLYIKSRTVEAPVEPQSTQ
                     QTAPDITAVTLPATVSAPPVTPAVVKSAFSTAQIDQWVAPVALYPDSLLSQVLMASTY
                     PANVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKVITTTKKAVPVKQTVTAPVIPSN
                     TVLTASPVITEPATTVISIEPANPDVVYIPNYNPTVVYGNWANTAYPPVYLPPPAGEP
                     FIDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHHHHDDDDYHHHDGGHRDGNGWQHN
                     GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVPYHDQDMAKRFHQTDVNGGMSA
                     TQLPAPTRDSQRQAAASQFQQRTHAAPVITRDTQRQAAAQRFNEAENYGSYDDFRDFS
                     RRQPLTQQQKDAARQRYQSASPEQRQAVREKMQTNPQIQQRRDAARERIQSASPEQRQ
                     VFKEKVQQRPLNQQQRDNARQRVQSASPEQRQVFREKVQESRPQRLNDSNHTVRLNNE
                     QRSAVRERLSERGARRQER"
     gene            complement(85629..87053)
                     /gene="lpdA"
                     /locus_tag="ACHY1N_000209"
     CDS             complement(85629..87053)
                     /gene="lpdA"
                     /locus_tag="ACHY1N_000209"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFS4042570.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     gene            complement(87378..89270)
                     /gene="aceF"
                     /locus_tag="ACHY1N_000210"
     CDS             complement(87378..89270)
                     /gene="aceF"
                     /locus_tag="ACHY1N_000210"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004742 - dihydrolipoyllysine-residue
                     acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFS4042571.1"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKETAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKIAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     gene            complement(89285..91948)
                     /gene="aceE"
                     /locus_tag="ACHY1N_000211"
     CDS             complement(89285..91948)
                     /gene="aceE"
                     /locus_tag="ACHY1N_000211"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008814576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004738 - pyruvate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HFS4042572.1"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     gene            complement(92109..92873)
                     /gene="pdhR"
                     /locus_tag="ACHY1N_000212"
     CDS             complement(92109..92873)
                     /gene="pdhR"
                     /locus_tag="ACHY1N_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HFS4042573.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIGLAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     gene            93414..94787
                     /gene="aroP"
                     /locus_tag="ACHY1N_000213"
     CDS             93414..94787
                     /gene="aroP"
                     /locus_tag="ACHY1N_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HFS4042574.1"
                     /translation="MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSA
                     GPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVL
                     YVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIK
                     VIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLE
                     LVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIF
                     HELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPV
                     NTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQG
                     VVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKT
                     AKAVKAH"
     gene            complement(94830..95684)
                     /gene="ampE"
                     /locus_tag="ACHY1N_000214"
     CDS             complement(94830..95684)
                     /gene="ampE"
                     /locus_tag="ACHY1N_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HFS4042575.1"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     GMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     gene            complement(95681..96232)
                     /gene="ampD"
                     /locus_tag="ACHY1N_000215"
     CDS             complement(95681..96232)
                     /gene="ampD"
                     /locus_tag="ACHY1N_000215"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HFS4042576.1"
                     /translation="MLLEQGWLVGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDCYPDIAKNMTGHCDIAPD
                     RKTDPGPAFDWARFRVLVSKETT"
     gene            96320..97213
                     /gene="nadC"
                     /locus_tag="ACHY1N_000216"
     CDS             96320..97213
                     /gene="nadC"
                     /locus_tag="ACHY1N_000216"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HFS4042577.1"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     SLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     gene            97416..97856
                     /gene="ppdD"
                     /locus_tag="ACHY1N_000217"
     CDS             97416..97856
                     /gene="ppdD"
                     /locus_tag="ACHY1N_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HFS4042578.1"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTHYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALHQACEDVFRFDDAN"
     gene            97866..99251
                     /gene="gspE"
                     /locus_tag="ACHY1N_000218"
     CDS             97866..99251
                     /gene="gspE"
                     /locus_tag="ACHY1N_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
                     /protein_id="HFS4042579.1"
                     /translation="MNIPQLTALCLRYHGVLLDASEEVVHVAVVDAPSHELLDALHFA
                     TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
                     EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
                     AGNAVSFRIATLPCRGGEKVVLRLLQQVSQALDVNTLGMQPLQLADFAHALQQPQGLV
                     LVTGPTGSGKTVTLYSALQTLNTADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGV
                     LRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
                     RWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPDNVWPSPLPHWQAPGCVHCYHGF
                     YGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
                     LIRVLGMPHGE"
     gene            99241..100443
                     /gene="hofC"
                     /locus_tag="ACHY1N_000219"
     CDS             99241..100443
                     /gene="hofC"
                     /locus_tag="ACHY1N_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HFS4042580.1"
                     /translation="MASKQLWRWHGITGDGNAQDGMLWAESRALLLMALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWSW
                     LLVLFGFLLAIANKLLMRRPTWLIVRQKLLLRIPIMGSLMRGQKLTQIFTILALTQSA
                     GITFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNTGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRDNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(100478..101521)
                     /gene="guaC"
                     /locus_tag="ACHY1N_000220"
     CDS             complement(100478..101521)
                     /gene="guaC"
                     /locus_tag="ACHY1N_000220"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFS4042581.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     gene            complement(101677..101721)
                     /locus_tag="ACHY1N_000221"
     CDS             complement(101677..101721)
                     /locus_tag="ACHY1N_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4042582.1"
                     /translation="MIIKTLKMSARKRN"
     gene            101746..102366
                     /gene="coaE"
                     /locus_tag="ACHY1N_000222"
     CDS             101746..102366
                     /gene="coaE"
                     /locus_tag="ACHY1N_000222"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308134.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFS4042583.1"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     gene            102366..103109
                     /gene="zapD"
                     /locus_tag="ACHY1N_000223"
     CDS             102366..103109
                     /gene="zapD"
                     /locus_tag="ACHY1N_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HFS4042584.1"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDTENGQVPERLDFELACC"
     gene            103119..103316
                     /gene="yacG"
                     /locus_tag="ACHY1N_000224"
     CDS             103119..103316
                     /gene="yacG"
                     /locus_tag="ACHY1N_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HFS4042585.1"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     gene            complement(103416..103805)
                     /gene="mutT"
                     /locus_tag="ACHY1N_000225"
     CDS             complement(103416..103805)
                     /gene="mutT"
                     /locus_tag="ACHY1N_000225"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008413 - 8-oxo-7,8-dihydroguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HFS4042586.1"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVESWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVIAKLKRL"
     gene            complement(103865..106570)
                     /gene="secA"
                     /locus_tag="ACHY1N_000226"
     CDS             complement(103865..106570)
                     /gene="secA"
                     /locus_tag="ACHY1N_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFS4042587.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTVEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     gene            complement(106632..107144)
                     /gene="secM"
                     /locus_tag="ACHY1N_000227"
     CDS             complement(106632..107144)
                     /gene="secM"
                     /locus_tag="ACHY1N_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="secA translation cis-regulator SecM"
                     /protein_id="HFS4042588.1"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLT"
     gene            complement(107375..108292)
                     /gene="lpxC"
                     /locus_tag="ACHY1N_000228"
     CDS             complement(107375..108292)
                     /gene="lpxC"
                     /locus_tag="ACHY1N_000228"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008759 - UDP-3-O-[3-hydroxymyristoyl]
                     N-acetylglucosamine deacetylase activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HFS4042589.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     gene            complement(108393..109544)
                     /gene="ftsZ"
                     /locus_tag="ACHY1N_000229"
     CDS             complement(108393..109544)
                     /gene="ftsZ"
                     /locus_tag="ACHY1N_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFS4042590.1"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     gene            complement(109605..110867)
                     /gene="ftsA"
                     /locus_tag="ACHY1N_000230"
     CDS             complement(109605..110867)
                     /gene="ftsA"
                     /locus_tag="ACHY1N_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFS4042591.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            complement(110864..111694)
                     /gene="ftsQ"
                     /locus_tag="ACHY1N_000231"
     CDS             complement(110864..111694)
                     /gene="ftsQ"
                     /locus_tag="ACHY1N_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HFS4042592.1"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPDRTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     gene            complement(111696..112616)
                     /gene="ddlB"
                     /locus_tag="ACHY1N_000232"
     CDS             complement(111696..112616)
                     /gene="ddlB"
                     /locus_tag="ACHY1N_000232"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFS4042593.1"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            complement(112609..114084)
                     /gene="murC"
                     /locus_tag="ACHY1N_000233"
     CDS             complement(112609..114084)
                     /gene="murC"
                     /locus_tag="ACHY1N_000233"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFS4042594.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     gene            complement(114138..115205)
                     /gene="murG"
                     /locus_tag="ACHY1N_000234"
     CDS             complement(114138..115205)
                     /gene="murG"
                     /locus_tag="ACHY1N_000234"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFS4042595.1"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERAR
                     AASIPDATERVANEVSRAARA"
     gene            complement(115202..116446)
                     /gene="ftsW"
                     /locus_tag="ACHY1N_000235"
     CDS             complement(115202..116446)
                     /gene="ftsW"
                     /locus_tag="ACHY1N_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HFS4042596.1"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     gene            complement(116446..117762)
                     /gene="murD"
                     /locus_tag="ACHY1N_000236"
     CDS             complement(116446..117762)
                     /gene="murD"
                     /locus_tag="ACHY1N_000236"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFS4042597.1"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDAECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGL
                     QVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     gene            complement(117765..118847)
                     /gene="mraY"
                     /locus_tag="ACHY1N_000237"
     CDS             complement(117765..118847)
                     /gene="mraY"
                     /locus_tag="ACHY1N_000237"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFS4042598.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGIAFALYLAGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            complement(118841..120199)
                     /gene="murF"
                     /locus_tag="ACHY1N_000238"
     CDS             complement(118841..120199)
                     /gene="murF"
                     /locus_tag="ACHY1N_000238"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFS4042599.1"
                     /translation="MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGK
                     QSHAISTASGVGEHFADKTALITRLKSLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     gene            complement(120196..121683)
                     /gene="murE"
                     /locus_tag="ACHY1N_000239"
     CDS             complement(120196..121683)
                     /gene="murE"
                     /locus_tag="ACHY1N_000239"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HFS4042600.1"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKGEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSEHHCGQAIVNADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     TEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     gene            complement(121670..123436)
                     /gene="ftsI"
                     /locus_tag="ACHY1N_000240"
     CDS             complement(121670..123436)
                     /gene="ftsI"
                     /locus_tag="ACHY1N_000240"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HFS4042601.1"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTIPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALTTGDKNEFVINQGEGTGGRS"
     gene            complement(123452..123817)
                     /gene="ftsL"
                     /locus_tag="ACHY1N_000241"
     CDS             complement(123452..123817)
                     /gene="ftsL"
                     /locus_tag="ACHY1N_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFS4042602.1"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            complement(123814..124755)
                     /gene="rsmH"
                     /locus_tag="ACHY1N_000242"
     CDS             complement(123814..124755)
                     /gene="rsmH"
                     /locus_tag="ACHY1N_000242"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFS4042603.1"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     gene            complement(124757..125215)
                     /gene="mraZ"
                     /locus_tag="ACHY1N_000243"
     CDS             complement(124757..125215)
                     /gene="mraZ"
                     /locus_tag="ACHY1N_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFS4042604.1"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     gene            complement(125817..126821)
                     /gene="cra"
                     /locus_tag="ACHY1N_000244"
     CDS             complement(125817..126821)
                     /gene="cra"
                     /locus_tag="ACHY1N_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009750 - response to fructose [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HFS4042605.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     gene            complement(126903..126989)
                     /locus_tag="ACHY1N_000245"
     CDS             complement(126903..126989)
                     /locus_tag="ACHY1N_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fruR/shl operon leader peptide"
                     /protein_id="HFS4042606.1"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            complement(127001..127492)
                     /gene="ilvN"
                     /locus_tag="ACHY1N_000246"
     CDS             complement(127001..127492)
                     /gene="ilvN"
                     /locus_tag="ACHY1N_000246"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HFS4042607.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     gene            complement(127495..129219)
                     /gene="ilvI"
                     /locus_tag="ACHY1N_000247"
     CDS             complement(127495..129219)
                     /gene="ilvI"
                     /locus_tag="ACHY1N_000247"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HFS4042608.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     MAGCHQQLKETVEALNLPVVSSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPHELESKLSEALEQVCNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            129338..129382
                     /locus_tag="ACHY1N_000248"
     CDS             129338..129382
                     /locus_tag="ACHY1N_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4042609.1"
                     /translation="MKRNDKILHYEGLN"
     gene            complement(129537..130481)
                     /gene="leuO"
                     /locus_tag="ACHY1N_000249"
     CDS             complement(129537..130481)
                     /gene="leuO"
                     /locus_tag="ACHY1N_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HFS4042610.1"
                     /translation="MPEVQTDHSETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     VLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQPWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
BASE COUNT        31785 a        35692 c        31960 g        31285 t
ORIGIN      
        1 ttgcgtttgt ttctgcctta agcaggttta ctgccccaaa ctactgcaat ccttattcgg
       61 gtaaaattta cccgccgtat cgggcgctaa tactttggtt ggcgcaccag tatccggatt
      121 agcctcaagc gtaaagtgac cttctactga cagtaacacc ggtttttcac tgtgaccgcg
      181 cgcagccagg tagctacgct ccagctctgc gttattcgct accatgaaac gttttccggt
      241 cgcgcaatca gtgaaggtcg ccgcatcagc catataaaaa tacatgcctc gcagggtcat
      301 cggcgtcata ggtaaactag attgtgccgg ttccagcgta tagttgaact gcgattcaat
      361 cggattgcct tcacgatcga gcatctccag cgcatcgcct ttcgcccgat aatatgactt
      421 ttcacctttg ctgtcggtta ataccagctt gtcagcggtt cgcgcccatg taccgtagga
      481 agcgaaggag gaaggttctt cacgagcacc gagataacgc tcattcatca cccatgttcc
      541 gtctttttcg aggaacagag aggtttcgat tccttcgcaa tcagcacacg gcagcacgcc
      601 gcgccaactt tgcggcatcg gtttcagttc ggcagcctgt gctggagaaa gcgtatcgac
      661 ttcggcccgg ttattacatc ccatcagagt aaagaggctg attacagcca tcgctgtcac
      721 tatcgctttt ttcaccatct attccttctt tttattcccg accgctgcgt actttgccgc
      781 gcatcgcctt cacgcttgat ttttgtgctt tcgatgccag cctgcgctct ttcgatgcac
      841 gggtgggccg cgtgggtcgt cgggcttttt gttctgttgt taaatcttta atcactgcca
      901 ccagccgggc tagcgcggct tcgcggttca gttcctgact gcggtattcc tgtgccttaa
      961 tgacaatcac gccatcactg ctgatcaaat gatggctggc ggcgagtaga cgctctttgt
     1021 aatactctgg caggctggac gcccgaatgt caaaacgcag atgaatggcc gttgaggtct
     1081 tattaacatg ctgcccgccc gcgccctgcg cacgaatggc ggtgatctca agctcaccat
     1141 cgggaatagc aacatgtcgg gaaatcacaa tcatgaaggt tgttgccagg cggttaagtt
     1201 aacttccaga ttattcttat cgtccgataa ccagatcacg ccatcctgaa tcgttgcctg
     1261 cagcgtcatg gtacgatcgg caaagacgct tactttcgcc agttgttcat cgtccagata
     1321 ccagacggaa agattggcaa actgcacaca tttgctctga ttttgctgcc accagatttg
     1381 cgccgcccga ctattatagg taaacagcgc cacttctgcg gcctgggtgc aggctttctt
     1441 aatccgccgc tcatccggca gccccagctc aatccacaaa tcaatgccca ggtgatcgtt
     1501 acgcagccac gcttccggct catcatcggc acacaaacca cgggtaaatt gcagacgttc
     1561 atcagcatat ttcagccacg ccagcaagcg cagcatcata cgctcctggg tttctgaagg
     1621 gtggcgcgcc agcgtcagag aggcatcgag aaactggttg cggtcgagat cggccacatt
     1681 aaccgtcgct ttataaattg tcgctttaag cgccataaga aaactccttt cgaatcagga
     1741 ggccattgta acggaatacg tgcagttgcg gcgctgatat tgcagaaatg agtgtggtat
     1801 agtcaccttg cgaaacagag tttatcttcg taggcttaga cttgcatcca cggttaagtc
     1861 agagtgctga caggagggca tgtggaaaaa tattgtgagt taatacgcaa gcggtacgcg
     1921 gaaatcgcca gcggagactt aggatacgtt ccggacgcgc tgggctgcgt tttgaaagtg
     1981 ctgaatgaaa tggctgccga cgacgccctt tctgaggctg tcagggaaaa agcagcatac
     2041 gctgcggcaa acttactggt gagcgattat gtcaatgaat gatacgtatc aaccaatcaa
     2101 ttgtgatgat tacgataatc ttgagctcgc ctgccagcat catttaatgc tgacacttga
     2161 gctgaaagat ggcgaaaaat tgcaggcaaa agccagcgat ttagtctccc gcaaaaatgt
     2221 ggagtatctg gtcgtcgagg ccgctggcga aacccgtgag ctacgtctgg ataaaattac
     2281 cagctttagc cacccggaaa tcggtacggt ggtggtgagc gagtcctgat taactttcgc
     2341 cggatgcgac gtttgatgcg tcttatccgg ctttcactta actaagcgtt ttctgccaga
     2401 caaaacttac gccattctca ccttcagcca caccttcttg cgtcacaaat acccctgccg
     2461 ccgcaatcag cgtttcgcca taaaacagca gtggcgtggt gtcacgtagc cacggcggca
     2521 cgcctaactc ttgccagatt ttcttcagct tacgtccgcc gttgcgcccg acaatatgca
     2581 gcaatcctgc cgctttgaaa cgcacgctga ccgcttcgtc tgcacgcgga gggcgaatat
     2641 cgcctcccgc agtaagctgt acgcttccca gccccgccgg taattccagc ggttgtagcc
     2701 acgtctgcca cggcacaatg gtttcacttt gcccggtgac ggatttaatc caccacagtt
     2761 gcgactgata gcggcggatt tcaaacgcgc ccaagcgtaa acagggggag gcatcttccc
     2821 gcgccagcgc cacttcctgc cagatccgca ccagcgcgtc gcgggaaggc attggtgcat
     2881 tctgccctgc cagccagcga cggataatcg ccgcgcggcg ggcatcactc atcgccagca
     2941 ttggcgcaat ctgcagcgtc ccctgcgacg tttggcagtg tgctaaatca tccgccagca
     3001 gttcatccaa cagactctct tgttcagcac aaagtgcggc gctgcgggcc gttgcttccg
     3061 caaaatgcgg ccaacgctgc tgcaataacg gcactacgcg caggcgcaga aagttacgat
     3121 cgtatgagtc gtcctgatta ctttcgtctt caatccagcg taaaccatgc gccaatgccc
     3181 actgctccag ttctccccgc gtgcgggcga gcaacgggcg gataagccgt gttccggcaa
     3241 actccgaaac ttccgccata gccgaaagcc cggcagggcc gctaccgcgt tttagcgcca
     3301 gcagaaaagt ttcacattga tcgtcgagat gttgcgcggt gaccagcact tcaccgggca
     3361 acaaggtgcg ggcaaatgcc tgataacgcg cctgccgcgc ctgggcctca atgcccagtc
     3421 cttcttgcgc aagttgcacg cgttcgacca ccagcggcac ctgccactgt tggcagacgt
     3481 tttcgcaatg cgtaacccag gcatcggcat tggcacttaa accgtgatgc acatgaatag
     3541 cgcgcagagt gacgcccgga ttttccgtcc gccactgcac caactgatgc agcagaacgg
     3601 tggagtcaag cccgccgcta aaggccacca gaatctggcg tgaggtgaga agttgtctat
     3661 tgagcgtgag tgtcatgatg gtgcgatttt acagtagcaa tgcccggcac gttaccgggc
     3721 aaatgcggcg atgacaagcc ttactgctca tacagttcca acggcagccc gtccggatcg
     3781 ttaaagaagg tgaagcgttt ttgcgtgtat ggatcgacac ggatggcttc acacttcacg
     3841 ttatggcttt caaggtgcgc cactgccgca tcgatgtcat caacgctaaa agccagatga
     3901 cgcaggccgc aagcttccgg tcggctgggg cgctccggcg ggaacggaaa agagaaaagc
     3961 tcaatcacat attgcccatt aagcgccaaa tcccctttcc acgagtcgcg cgcttcgcga
     4021 tagacttcgc tttgcagcgt gaaaccaaga atatcgcagt agaaagcttt gctcaccgca
     4081 taatccgtcg caataatcgc aatatggtga acctgtttta aacccagcat aacgtctcct
     4141 ttatttgtta acagcacgtt actcgcccgg aagccgctct ggcaagttat cccgccattt
     4201 ttaggactcg tacgcggtaa acgccgtctt cgtcctgttt cgcgccgtga atatccgttt
     4261 caaaaccggg gtaatgttgc actacggaac aaagcatcag tagaaaatcg agtaccgtgc
     4321 ggctctcttt ggtcagcatt tctcctggca tcaacagcgg tacgcccggt ggataaggca
     4381 ggatcatatt tgccgatact ctaccgacca gttgttccag cgcaatggtt tctacttcac
     4441 ctttaatctg tctctgccat gcctgatgtg gcgtcatgat catttccggc aaagtatcga
     4501 atgcccgcaa catcaaaccg ggaagatcgt gtttacgaat cagcttatgg atcccttgcg
     4561 ccagatcctg aatacgcata ttgcggtaga aatcgggatc ttcagcatag agatcgggta
     4621 gcatattttt gatccgcagg ttgagatcgt aagagcgttt aaattccgtc aacccacgca
     4681 ataatcccat tgctttggtt ttatcgatac caatactaaa gagaaacagc aggttataag
     4741 ggccggtttt ctctactacg atcccacgtt cgtcgaggaa ttttgccacc agcgccgccg
     4801 ggatcccctc ctcgctcata ttgccctgtt cgtccatccc cggtgtcaaa atagtgactt
     4861 taaccggatc gagaaacata tgatcggcat ccgcatcgtt aaagccgtgc cactgttcgc
     4921 ctggcgcaac gggccagcat tcggcttcat ccacctgcgg cggttgccag atatcgaaaa
     4981 accaaccgtc agactcttcc cgcaaccgct ggacctcttt gcgaaaatgc agcgcccgct
     5041 ccaccgaacg gttaatcagc cgtttgcccg gattaccacg cagcatcgcc gccgccgtct
     5101 caaccgaagc aacaatggga taactgggcg aggtggtggt atgcatcata aaggcttcgt
     5161 taaacgcctc ttcgtcatac tcgcctttaa tgtggatcag cgaagcctgc gataacgccg
     5221 ccagcatttt gtgggtcgat tgcgtttcga agatcacttt tcccgcaaca cgctcgccgc
     5281 tcataccact tttcccctgg tagatcggat gaaaatgggt gtacggcacc caggcggaat
     5341 cgaagtggat cgacgggaca tccagcgtct gtttgatcca gtcggtgttg tagagcaagc
     5401 catcataggt ggagttggta atcaccgcat gaaccggcca ttgtgcctgc gtggtggcag
     5461 cgactttctc ttcgatgctg tcgcgagtaa attcacggcg cgggatccca ccaagaatcc
     5521 ccaacgcatt acgcgtcggt ttcagccaga ctggcactac atcgttcatc atcaacagat
     5581 gcgccagcga tttatgacaa ttgcggtcga tcaacagcgt actgccggat ggcgcggcgt
     5641 acatacccac aattttgttc gacgtcgatg ttccgttggt aacgatataa ctctgttccg
     5701 cgccaaaagt ccgcgcgatg tactcttccg cttccaggtg tggcccggtg tggtcgagca
     5761 acgaaccaag ctcggtgacc gaaatagaga catcagcctt gagggtattc ccgccgaaaa
     5821 aatcataaaa caggcagcca accgggcttt tttgatatgc ggtgccgccc atatgccccg
     5881 gcgtacaaaa ggtgtacttc cgctctttga cgtaggtaaa caaggctttc gtgaacggcg
     5941 gtgtaatgtt atcaagatat tcgtcggtgt actgacgcat acgaatggcg atatcttccg
     6001 cctgccccag cgcatattca aaaaaccaga gcgccatccg catatcctgc acgctgacat
     6061 ccatcgtcga gtgggtgttg atgaaggcat aaagcgggag atattcatta agttgattga
     6121 tatcgctgca taaatcgaga ctgtactcat cccagtcaaa aatcacgccg caaattcgag
     6181 ggttatgttc gataaatttc agcaaatcaa cgctgttttg tggccagata atctgaaagc
     6241 cttgcgccac cagcgccgac tccagttctt tgatgggctc atctttataa aagacgccat
     6301 gcggtcccat aatggcaatg atgttcatgt gttcctcctg gaaaatcctt ccttaatcat
     6361 agcctgctca aaccgtggcg ataaaaaagg gccaccgaag tgaccctttt tcagaacttt
     6421 tgcgaattac gcgtaaccgt agctcatcag gcgctgataa cgacgatttt ttaaatcttc
     6481 agtgcttaac acatcgagat cggccagatc cgccagcagt tgcgctttca acgatgccgc
     6541 catcgcttcc gggttacggt gagcaccacc cagcggttcc gggatgatgg agtcgatcag
     6601 ttttagttct ttcagacgcg gagcgatgat acccatcgct tcagccgcca gcggcgcttt
     6661 atcagcgctc ttccacagaa tggacgcaca accttccggc gagataacgg aataggtgct
     6721 gtattgcagc atattcactt tatcgcccac gccaatcgcc agcgcgccgc cagaaccacc
     6781 ttcaccgata acggtacaaa tagtcggtac gctaaggcga gacatttcac gcaggttgcg
     6841 tgcaatggct tcagactgac cgcgctcttc tgcgcccacg cccggataag cccccggggt
     6901 gtcgataaag gtgatgattg gcatcttaaa gcgttcagcc atttgcatca gacgcagtgc
     6961 tttgcggtaa ccttctggcg ctggcatacc aaagttacgg cgaatttttt ctttggtttc
     7021 acgacctttt tgatgaccaa tgatcatcac cggacgaccg tcaagacggg cgataccacc
     7081 gacgatagct ttatcgtctg catacgcgcg gtcgccagcc agttcgtcaa attcatcaaa
     7141 tgccaggcga acgtaatcca gggtataagg acgctgtgga tggcgtgcca gttgcgcaat
     7201 ctgccatgca ccgagatcgg cgaagatttt acgtgtcagt tctacgcttt tttcacgcag
     7261 acgatgcact tcttcatcga tgttaatatc cagtttctca tcctgacggc taaccgcagt
     7321 cagagaatcg attttcgctt ccagctctgc aatcggctgt tcaaaatcaa ggaaattcag
     7381 actcatagta ttcctgtatt agtcaaactc cagttccacc tgctccgaac caatgaggcc
     7441 acggagatcg tttaataaac gatcgctcgg agagacacgc cacgtcgcgc caaaacgcaa
     7501 ccgcgcgcgt gcatccgccc tctgatagta gagatgtact ggaattgtcc cagagcggtg
     7561 gggttccaga gactgacgga gtcggtttaa aagctggtca tcaatttgcc tgtccgtcag
     7621 cgagatagca agcccgcgag catatttttc ccgggcttcg tcaatatcca tcacttcgcg
     7681 agcggtcatt ttaagcccac cgctgaagtc atcaaagctg acctgtccgc tgacgataag
     7741 tatgcggtct ttttccagca attgctggta tttatccagg gcgtcagtaa acaacatcac
     7801 ttccagccgc ccggaacggt catccagcgt gcagataccg atacgattgc cgcgcttggt
     7861 gaccataacc cgcgcggcaa caacgagccc cgcagccgtg atgactttac cacgttctgt
     7921 cgggtgcatg tctttcagcc ttacgcctcc gacataacgc tcaatctctt ttaaatactg
     7981 gttgataggg tgtccggtca ggtacaggcc taacgtttca cgttccccat ctaataccac
     8041 ctgctccggc cacggttggc agctggcgta ggattgttca atttgttccg gctcttcggc
     8101 cagcacgccg aacatatcgg cctgaccgat agcttccgct ttcgcgtgtt gatctgccgc
     8161 ttttaacgca tcacccagcg agttcatcag cgccgcgcga tgtggcccaa gacggtcaaa
     8221 cgccccggac atgatcagtt tttccagcac gcgacggttc aactttttgg tgtcggtacg
     8281 ggcgcagaga tcaaacagtt cgcggaagta gccgccttta ttacgggctt cgatgatggc
     8341 ctcaatcgga ccttcaccga cccctttgat cgcgccaata ccatacacga tttcgccgtc
     8401 gtcgttgacg tggaaatggt aaagaccgga gtttatatct ggtggcagga ttttcagccc
     8461 catccgccag cactcatcca ccagacccac caccttctcg gtgttgtcca tatcggcggt
     8521 cattaccgcc gccataaact ccgcaggata gtgtgctttc agccataacg tttgatatga
     8581 caccaaagca taggccgcag agtgcgattt gttaaatccg taaccagcga atttctccac
     8641 caggtcgaag attttcatcg ccagttcagc gttgattccg ttcttttctg caccttcagc
     8701 aaatacagaa cgttgcttag ccatctcttc cggctttttc ttccccatcg cacgacgcag
     8761 catatccgcg ccaccgaggg tataaccaga aagcacctgg gcaatctgca tgacctgttc
     8821 ctgatacagg atgatgccgt aggttggctc cagtaccggt ttcaagcttt catgctgcca
     8881 ctgcacgtcc ggataggaga tctcttcacg accatgttta cggtcgataa agttatccac
     8941 catccctgat tgcaacggac cggggcggaa cagtgccacc agggcgatca tatcttcgaa
     9001 gcagtcaggt tgcagacgct tgatcaggtc cttcatgccg cgcgattcaa gctggaatac
     9061 cgcagtggtt tccgagcgtt gcagcatgtc gaagcttttc ttgtcatcca gcgggatcgc
     9121 ggcgatatcc agcggcggct cgccattctt cgcccgccgc ttgttgatca tctccagcgc
     9181 ccagttgatg atggtgagcg tacgcaaacc aaggaagtcg aacttcacca gtccggcgta
     9241 ttcaacgtcg cttttatcaa actgggtgac cggatgtttg ccctcttcat cgcaataaag
     9301 cggcgcaaaa tcggtaattt tggtcggtgc gataaccacc ccaccggcgt gcttaccggc
     9361 gttacgggtg accccttcca gtttgcgcgc catgtcgatc agcgccttaa cttcttcatc
     9421 cgcttcgtag atttccggca gctgcggctc ggcttcaaac gctttcgcca gcgtcatccc
     9481 cggatcgggc gggatcagtt tcgagatacg atcgacaaag ccgtacggat gccccagcac
     9541 gcggcctacg tcgcggatca ccgctttcgc cgccatcgta ccgaaggtga taatctgcga
     9601 taccgcatca cgaccgtaca tgtccgctac gtgctcgata acctgatcgc gtttctccat
     9661 acagaagtca acgtcgaagt caggcatgga gacacgttcc gggttaagga aacgttcgaa
     9721 cagcaggtca aattccagcg gatcgaggtc ggtgattttc agcgcgtagg ccaccagtga
     9781 acccgcaccg gagccacggc ctggccctac cggtacgccg ttatctttcg accactggat
     9841 aaattccata acgatgagga agtagcccgg gaagcccatc tggttgataa cctgaagttc
     9901 agtctccaga cgttcgtcat attccgggcg gcgcttaaga cgttcttcct catcagggaa
     9961 taaaaaggcc agacgctctt ccaggccctc ttttgcacgc ttgaccagat aatcttcggt
    10021 gctcatgtcc ccggtcggga actgcggcag gaagtattca ccaagacgca cggttacgtt
    10081 acagcgtttg gcgatctcaa cggtgttggc aagggcttcg gggatgtcgg caaacagctc
    10141 acacatctcc tcttcgctac gcatatattg ctgcggcgaa tagttacgcg ggcgtttagg
    10201 atcgtcgagg gtaaagccgt cgtggatcgc gacgcggatt tcgtgtgcgt caaagtcgct
    10261 gctgtcgata aagcgcacgt cgttggtcgc cacgacgggc aaaccgcgcg cttccgccag
    10321 ttccaccgcc gcgtgcagat agctttcttc atccggcctg ccggtgcgga tcagctcaag
    10381 aaaatagcga tccgggaagt gttcttcata aaacgcgaca cactcatcta ccagcgcgct
    10441 gttaccacgc aaaagactgc gtccgacgtc gcccatgcgt ccgccggaaa gaaggatcaa
    10501 cccttcgttt aattcgataa gccagtcgcg atcgatgatc ggcccggcgg caccgtaccc
    10561 gcgctgatac gcttttgaga tcagcaacgt cagattctga tagccggtat tgttcgccgc
    10621 cagtaccgtc aggtgggtta actcatcacc cagcaggtcg cactggacgt taaaatctgc
    10681 cccgacgata ggcttaatcc ctgcgccatg tcccgctccg tagaacttca ccagaccaca
    10741 aaggttggtg aaatcggtga tcgccagtgc tggcataccc aacgccgccg ccttttttac
    10801 caacggtgcg gttttggcca ggccatcgat catcgagtag tcgctgtgca cccgcaggtg
    10861 tacgaaacgt ggttcagaca tcttcagatt ccggtttact taatctcgac acaagaatca
    10921 ggacgcaagt cccagtgcgc gtttgacagg cccaaagctg cgccgatggt gttcggtcgc
    10981 gccgtgttca gccagttttt ccagatgaaa agcggttggg taccctttgt gttgggcaaa
    11041 accatattgc gggaaaacaa tatccagcgc cgccatttcg gcgtcacgcg tcactttcgc
    11101 caggatagac gcggcactga tttccggtac gcggctatcg cctttcacca cagccatcgc
    11161 aggcatcggt aatttcgggc agcggttacc atcaatcaac acatattccg gcgcaatatg
    11221 cagcccagcg acggcacgct gcatcgccag catggtcgca tgaagaatgt tcagctcgtc
    11281 gatttcgtgg ggttccgcgc ggcccagact ccagctcaac gctttctctt tgatctcttc
    11341 atagagcgcc agacggcgtt tttcgctcag ctttttggaa tcattcagcc cggcaatcgg
    11401 gcgcgccggg tcaaggatca ccgcagcggt gacgaccgcg ccaactaacg gcccacgtcc
    11461 gacttcatcc acacccgcaa ccagctgcgt gtgcggataa acaaattcga tcattgtgct
    11521 aactccagaa cggcttgtgc cgcctgctca tcggcattgc agcggatctg ctgatgcagt
    11581 tcacggaagg tatcgtgcat cgcgtggctg gttttcccgt tcgccaacag cggtaacagc
    11641 gccgcagcca gtttttgcgg ctcacactct tcctgcaata attctttgac taactctctg
    11701 cccgccagca gatttggcag cgagacataa tcagttttca ccagctgctt cgccaaccag
    11761 aaggtaaaag gcttcatgcg atatcccacc accatcgggc atttcgccag catacactcc
    11821 agggctgccg tacccgacgc cagtagcgcc gcatcgctgg cgaccatcgc ctcacggccc
    11881 atcccatcca gcaaatgaac tgaaaggtct ggcgcgactt cagctttgat gcgttcaaac
    11941 tgctcgcggc gtttggcatt caccagtggc accacgattt cgagatccgg atatgtctgg
    12001 cgcaaaagct gggccgtttt caggaaatcg gcactaagca tttcaacttc tgcaccacgg
    12061 ctccctggta gcaacgccag gcagtgggca tcgtgaggga tccccagcac atcacgggcg
    12121 gcatttttat ctggatctaa cggcatggca tcagccatgg tatgaccgat aaagcggcac
    12181 ggtacattgt atttgtcata aaacgctttt tcgaaaggca gaaatgcgag caccagatcg
    12241 gtggctctgc ctattttgaa aacgcgtttc tgtcgccacg cccagacgga tggactgacg
    12301 taatgaatgg ttttgatacc ctgctttttg aggttacctt caagagtaat attgaagtca
    12361 ggcgcatcaa taccaacaaa aatatctggc ttcagttcgc caaaacgctt tgtcagatcg
    12421 gcacgaatat gcagtaagcg acgcagacga ccgagcactt caacaatgcc catcaccgcc
    12481 agttcttcca tttcgtacca ggcttcgcag ccttcagcct gcattcgtgg cccggcaaca
    12541 ccaacaaagc gggcgttggg cacacgttct ttcagagcgc ggattaaacc ggcccccagg
    12601 atatcgccgg aggtttctcc ggcgaccagg gcaatcgtta atggacgctg ttcagtcatt
    12661 aacgaatcag accgcgcgtt gagcgtgcaa agaaatcggt aaaggctttc acttccggat
    12721 atgtttccgc cagttcagca atttccggtt tcacttcatc gagcgtttta ccgctacgat
    12781 aaatcagctt atacgcattg cggatagcgg taatcgcctc acggctgaat ccgcggcgct
    12841 tcagcccttc gatattgaca ccgaacggcg ttgcgtggtt accctgcgca atgacataag
    12901 gagggacgtc ctgcgccaca ccggagcagc cgccaaccat cacgtgcgca ccaatgatgc
    12961 agaactgatg gactgcggtc atgccgccga tgatcgcgaa gtcgtcaacc gatacgtgac
    13021 ccgccagcgt tgcgttgttg gcgagaatac agcggttacc taccgtacaa tcgtgcgcaa
    13081 tgtgcgcgtt gatcatcagt aagttgtcgc tgcccacctt cgtcaatcca ccgccctgga
    13141 ctgtgccacg atgaatggtg acgctttcgc gaatgcggtt acgatcgccg atttccacac
    13201 gggtcggttc gccagcatat ttcagatcct ggttaacttc gccgatggag gcgaactgat
    13261 aaatctcatt atcgcggcca attttagtat gaccattcac gacaacgtga gatttcagta
    13321 cggtaccctc accaatttcg acatggggtc caacgataca aaaaggacca atgtgtgcgt
    13381 tcgcgccaat tgacgcgccc tcttccacaa tggcggttgg atgcacaaag gcggatttat
    13441 caatcactta tcaggcctcc cggctacgag cacacatcat cgttgcttcg caaactactt
    13501 taccatcgac cagagcaacc cctttaaaac gggtcaggcc gcggcgcgtt ttttcgaaag
    13561 tgacttccat gatcatttga tcgccaggca cgaccgggcg cttgaagcgc gcttcgtcaa
    13621 taccagcgaa gtagtacagc tcacccggtt ccagttttcc tacgctttta aacgccagaa
    13681 tacctgttgc ctgtgccatt gcttccagaa tcagcacacc cgggaaaatc ggttttccag
    13741 ggaaatggcc ctggaagaat ggctcattga cagagacatt ttttactgcg cgcagaaaac
    13801 gaccttcttc aaaatccagc acgcgatcca ccagtaagaa cgggaaacgg tgcggcagaa
    13861 gttctaaaat ctcttcaatc tgcagagtat gagtgttagt agtcaagata ctcttcctgt
    13921 caaaatataa gaaacgacaa taataacacg gcctgccgca atcgtaagaa tgagacaggc
    13981 cgtaaagttt ggcgaacaaa agatggaacg ttagtcttgt tgattaacct tgcgctcaag
    14041 cgatttcaga cgcttgctca tgtcatcaat gttcatcacc agtgcagcgg ttttgcgcca
    14101 gactttgttg ggttgcagcg gaatgcctga ggaatagacg cctggttcag tgatgggacg
    14161 catcaccata cccatgcccg taaccgtcac tttgtcgcat atttccatat gcccgttgat
    14221 tacgctggct ccgccgatca tgcagtaacg accaattttc aggctgcccg ccataatgac
    14281 gccaccggca accgccgtat tgtcgccaat cacgacgtta tgtgcaatct ggcactggtt
    14341 atcaatgatc acgccattgc caataacagt gtcatccagc gcgccgcgat cgatggttgt
    14401 gcaggcaccg atctccacgc gatcgccaat aattacgcga ccaatctgtg ggatcttcac
    14461 ccagttacca cgatcgttgg cataaccaaa gccgtctgcg cctaccactg ttccggactg
    14521 gatcaggcaa ttctgaccga tctggatctc atggtaaatg gttacgttcg cccagagacg
    14581 cgaacctgca ccgattttgc tgtttttacc tacgaagcaa ccggcaccga taatcacgtt
    14641 atcgcccagt tcaacgccgg actcaatcac cgcgttagcg ccaatcgata cgttgttacc
    14701 cagctttgcc gtcgcgtcga tcaccgcact gggtgcaatg ttctgcgcgg gctgcggcgt
    14761 ggtatctaaa atttgcgcca tgcgcgcgta agtcaggtag ggattcttca ctaccagcgc
    14821 ggcacttttc gcgaaaggaa gatcgtcctg ggtcatgaca accgcggacg cctggcacaa
    14881 gcctaaatgc tcacggtatt ttgggttaac catgaacgta atgtgacctg tttgtgcaga
    14941 ttgcatggac gcaacgccgg tgatgacgat atcgccatca ccgtgtagtt ctgcatccaa
    15001 ctgctgcgct aaatcagcca gtcgaattga aggcattact tatttaacct gtttcagtac
    15061 gtcggcagtg atgtctttta catcgctgct gttgtaagca acggcgtttg catcaacaac
    15121 cagatcgata tcctggctgt tggcaacgga tttcacagca gtctggatac gagtaaccag
    15181 tttgccgcgt tcttcgttgg aacgacgtgc gcgatcctgc tcaaaagcct gcgctttctg
    15241 agcaaaagtc tggcgctgag ccatcacgtc tttttccagc ttagtgcgat cgctgcccgc
    15301 tttcatggac tgcagctttt tcattttagc ctgcagatcg gtttccatac gctgcagttc
    15361 gctggcacgg cctttgaact cattttccag cgtgttagaa acaccggttt tctgcgctac
    15421 ctgctggaac aggctgccca tgttgacgat tgcaattttg tcagccgcct gagcagaagt
    15481 tgccagtgct aaaccgagac ctgcagctaa taaccacttt ttcacaataa actccttacc
    15541 atcccatttg caccggaggg tgcagttctt tgcgtggccc ggcgatctta tattgatcgc
    15601 ctaaagtcat cgctacacta ccactacatt cctttgtgga gaacacttac caggttttac
    15661 cgatgttaaa ctggaactgt tctgccttgt ctccatcgta ctttttgaac ggctgggcgt
    15721 aggagaacac caacggcccc aatggggaca tccattgtaa tgcgataccc gcagacatac
    15781 ggatattgct tggatcacta tagtccggat atccagaata ttggctggaa tcccagtttg
    15841 tatcccaaac ggtacccata tcccagaaga aggaagtacg aaccgagtta gcatacttat
    15901 cgctaataaa cggcgtcggg gtgatgaact cgaggctggc aaccgccatg gcgttaccgc
    15961 ctacagcatc atccgattta cacaggtctt tcgcgccgtc ctgagtcgca cattcgtaat
    16021 catagtccgg atcataatta ctggcctgat gcgggaagta aactgctttc ggaccaattg
    16081 tattggactg gaagccacgc acggtgctgg aaccaccggc atagaagttc tcgtagaacg
    16141 gcatctcttt gccgcctaaa ccatcaccat aaccccagcg ggtacgcccc agaacaaccc
    16201 atttgtgatc gtcatcgatc ggcacataag tcgccgtgtc taacgtcact ttgtagtatt
    16261 cgttatccga tccaggaatg gtcactttac cggtcaggtt gacacgtgaa ccatctgtcg
    16321 ggaagtaacc acggtcaagc ttgttatagg tccaaccata gttgaacgtg aagtcgtccg
    16381 ttttgaagct attatcctga tcagaggtgc tcggatgttc acccatagag tacagataac
    16441 gccacatcgc aacctgaggc tgcatgttgg acagggagtt atgtacataa cccagacctg
    16501 cacgcagcga gttatattcg ttgatcggga agcccaacgt cacgtctgta ccataactct
    16561 tgttggtata gtcggacagg tcggcgtcat ctgcctggaa gtcattatag aagagacgac
    16621 caccgaggct tacaccatct acagtgaagt acgggttggt taccgacagt tcagcatagg
    16681 tctggtaatc gtttttggtc ccgttgatac caacagcata acctgtacct aaccagttat
    16741 cctgctgcac accagcctgg aagctcacgc cactttcagt accgtaacca atcccgaagt
    16801 tgaagctacc ggtgttacgt tctttcacct tgtagactac atctacctgg tccgggctac
    16861 ccggaacacg ttgggtatcg gtatcgacag tttcaaagaa gcccagacga ttcagacgct
    16921 ccttaccctg atcgaccaga tcgctcccca gccatgcacc ttccatctga cgcatttcgc
    16981 gacgcaggac ggcatctttc gaggtatcgt taccttcaaa acggatctta cgcacgtaga
    17041 aacggttacc cgcatcaacg ttcacacgta atttaacggt tttgtcggca tcgttaattt
    17101 cgggcatcga ctgtacgcgc ggataggcat aaccatagcg accgagaagc tttttgatgt
    17161 catcttccat cttggtcact ttggtgccgt tatacagctc acccggctcg atcttagtca
    17221 gctgctcaat ttcagcggag tgcccggcaa ggttgccgct cacttcaacg ccagaaagct
    17281 tgtactgatc gccttcggtg atgttcaccg tgacgtaaat acctttttta tctggcgtca
    17341 gactgacctg ggtagagtcg atgttgaaac gggcataacc gcgatccaga tagtagctgc
    17401 gcagggtttc aaggtcgccc gccagtttct gtttctggta tttacgatcg cctaccacgt
    17461 tccaccacgg cacttcgtca cgcagttgga aatgagagat cagttcgtcg gtggtgaaag
    17521 catggttacc aacaatgtta atttgctgga tttcagctga cacaccttcc tggaacacca
    17581 gttttaggtc aacacggttg cgcggcagcg gggtcacgac agcttttacg ctggcgctat
    17641 atttaccgac gctgtagtag aagtcttcca gacctttctc gatatcggca atggtggtgc
    17701 gatcgaggga ttcgcccaca cgcacaccag aagcctcgag gttttgcttc agcatgtcat
    17761 ctttcaccga tttgttaccg gagaaagtaa tgctggcaat ggtcggacgt tcttttacct
    17821 gaaccagaag ggtatcacca tcacgaagga cgcgaacatc ctcaaagttg ccggtagcaa
    17881 acagagcgcg aatggtatta ctgatatctt catcattaac cgtgtcgcct gtgcgcaccg
    17941 gcatactgag gagggccgca ccaacggcga cacgctgaag gccttcgaaa tgaatatctt
    18001 tcactacgaa cccttcagca ccgtatacgg tggcgctgct aaacagcagc gacgctatga
    18061 gcaacttttt catcgccatc gttattatgc gttcttccta actaactctc ataaccgaga
    18121 gaaatcattg aaaagtgcaa gccccattaa cagcaccagc agaatcgagc caatgcgata
    18181 acaaaagtct tgaacccgct cggataccgg tccgcccttg atcttttcga tcgcaaggaa
    18241 cagcagatgc cccccgtcaa gtacgggcaa cggaaacagg ttaattatcc ctaagttcac
    18301 gctaataagc gcaagaaacg gcaggtaata aactaccccg agttccgctg tcatcccagc
    18361 ccccttggcg atagagatcg gcccactgag gttgttcagt ttcacatcac cggtgatcaa
    18421 ttttcccagc atactgaccg tcagcttcat cagctgccac gttttgtccg tggcttcgac
    18481 gatggcgttg aacggcccat actggcgtac aactttatac tcatctggca aaggaatgac
    18541 tttcggctca ataccgacaa aaccaatcgc tttaccatta cccggtttac tctccgggat
    18601 taatgtcaaa gacaagggac ttccctgcct ttcgatttct aacgctaagg atttacccgg
    18661 gttatcccgg acaagcatca caaaggtcac ccactgcgtt aagggctgac catcgacttt
    18721 aacgatcctg tcgcctgctt gcaaacctgc cttgcttgcc gccgagtttg gctgcacatt
    18781 ttccagtaca ggttcaattt gcggcccacg aggacgaatc cccagcgaag ataccggatc
    18841 ttctttatca ggctcaaacg cccagtgacg taaatcgagc tttacatccc gccgttgatc
    18901 gctgccaaat ggcgctactg taatggtggt gctttcatcg ccaattttat cgaccaactg
    18961 caaacgcacg gcatcccaat caggcgtttc gataccatct acggctttta gttccgtacc
    19021 tggtgcaatt tgtgcttccg cagctatcga attggctgct atttcaccaa ccaccggacg
    19081 tacgccaggc acaccaataa taaaaaccag ccagtaggca aagatagcaa aaatgaagtt
    19141 tgcaaccgga cctgcggcaa taatcgccgc tcgttggcca acagatttat tattgaaggc
    19201 atggtggcgg agttccggaa cgaccggttc tgcgcgctca tccagcattt tgacataacc
    19261 gcccagcggg atcagggcga taacatattc ggtgccgagc ttatcagttc gccgccagag
    19321 cgccttacca aaccctattg agaaacgctc aacgcgaaca ccacaacgcc gggcaaccca
    19381 gaaatgacca aattcatgca cggtgataag tacacccagt gcaacgatga acgaagccaa
    19441 atcccagaga aaactcagca tattaccttc cgttaaagcg tcctgaatac cagtaacaac
    19501 aagcaagcaa agaccggtac cgcagccgtc aggctatcaa tacgatctaa aataccaccg
    19561 tgtcctggaa ttaaatgacc gctgtcctta attcctgctt cacgcttaaa catactctcg
    19621 gtcagatcgc cgagcactga ggctaacgct gcgacaatag agcaaatgag taaggtgacg
    19681 ggagcgacgt cgagattcgc ccacatgcca taaccccatg agattaccgc tgcggtcgct
    19741 agtccaccta taaagccttg ccaggtttta cccggagaaa ccttcggtgc cagcttatgt
    19801 ttaccaaaca atttgccaaa catatatgcg ccagagtcag cgccccatac caggatcatg
    19861 acatagagca gccatattgc gccactgtaa tgattctcgt cgtagtgcca ggcccgtaac
    19921 gccagcatgc cccagaagaa gggaacaatg gttagcacgc caaaaataag gcgcaatgtt
    19981 ttagagttac gccagattgc tgcggaacct gggtaaaaca gcaccagcaa tagcgcgaca
    20041 atccaccaac ccagcgaagc ccaaagtgag atttcaacca gcggttgatg aatatttcgg
    20101 tgatattccg gcaacagaaa aagcatcagc gccaacaata acccgcataa caccgccaac
    20161 catactcgct gcgaacgagt ggtaaaaccg ctaagctgtc cccattccca cgctgccagc
    20221 atgcagacca ccagcgttac gatggcgaac cccaccggcg gcaacagaaa caacgccgcg
    20281 atgacgacgg gtattaacac aaaagcagat atcaggcgat acttcagcaa aagcgacccc
    20341 catcaggctg tttcatcacc gggctcggtg ccgccgaaac gacgctctcg attagcaaag
    20401 gcatttaacg ccccttcaaa gtcttgttca tcgaaatcgg gccagagaac atctgtaaag
    20461 taaagttcgg cataggcaat ttgccaaagc aaaaagttac taatgcgatg ctccccccca
    20521 gtcctaatta ctaaatctac aggggccagt tcatgcatac agacatgctg gtttagcatc
    20581 tcttcatcta tctgatctgg ttgcaggttt ccttgctgca ccttttcagc cagttgcctg
    20641 actccctgga ctatatccca acgtccaccg tagttcgccg caatattcag cgtcagaccg
    20701 gtattcccgg ctgttagcgc ttcagattta cgaatacgtt cttgcaaacg cgagttaaag
    20761 cgactggtat cgccaataat acgcagacgc acgttatgtc ggtgcagact ttttacttcg
    20821 ctatcgagcg cccacacaaa cagttccatt aacgcactga cttcctgcgc tggtcggttc
    20881 cagttttcac tactaaaggc atacagcgtt aacgcctcaa taccgttgtt ggccgcaaaa
    20941 gagacagccc ggcggacgga ttttgccccg gctttatgcc caaaggcacg aatcttccct
    21001 tgcttttttg cccagcgacc attgccgtcc ataatgatcg caacatgacg gcagccatgc
    21061 gctggcaatt tttcgctaag tggttgagta gcagacaaca tcacgcgttt tttattccct
    21121 gacagggttt acggtactca ggaatactga agcctataca aaaaaaagcc gtgtaaaacc
    21181 acggcatacc tgaccttata aagccaacta cttacgatca gatggcgcag actatatcac
    21241 tgaagcccta cgctaacaaa tagcgcgact ctctgtagcc ggattatcct cagcttgcga
    21301 gacgcatcac ctcttttctg gcgacttcac gcgcgttcgc atcaacagat aacacatcgt
    21361 ccacacattg tggttcgcgc atatccattt tttccagtac cgataaattc aacgcagcga
    21421 tatccgtaaa gcggatttgt tgcgcaagaa aagcagcaac ggtgatttcg tttgcggcat
    21481 tcaatgctgt cgtcgctgcc tgaccttgtt cgaacgcctc catcgccagt ttcaggcatg
    21541 gataacgatc ataatccggt gcggcaaatg tcaacgcact tagtttgcaa aaatcgagcg
    21601 gcttcacgcc agagttcacg cgattcggcc atgccatggt gtgggcaatt ggcgtacgca
    21661 tatccggttc ccccagctgc gccagaacac tgccgtcctg atagcgcacc attgagtgaa
    21721 tcactgactg cgggtgaatc agcacttcca tctggctggc gctggcgtta aacagccaac
    21781 gcgcttcaat gtattccaga cctttgttca tcatggtagc cgaatcgaca gaaattttac
    21841 gccccatcga ccagttcgga tgacggcagg cttgatccgg cgtcattgtt gccaaatcgc
    21901 gcaatggcgt ctcacggaaa gggccaccag acccggtaag taaaatggac accacgccat
    21961 tttgctcaag gtcagcgtat cccagattat gctggatagg ttgcggtaaa ctctgaaaaa
    22021 tggcgttatg ttcgctatcg accggtaaca attgcgcttt gctctgcttt acggcgtcca
    22081 taaacagacg tccgcaggta accagtgatt ctttattggc cagcaaaatg gttttacccg
    22141 cgcggatcgc agcaagcgta ggtaacagcc cagcagcgcc aacaatggct gccatcacct
    22201 gatcaacatc ctcaagcgct gccatatcgc aagcggcttg ttgcccactt aagacttcgg
    22261 tgcggctacc ctgttgctgt agcatcgttt taagaagttt cgcactcgct tcatcgtcca
    22321 ttacggcata gcggggagag aattccaggc actgttctac catgcgagtg acatttttgc
    22381 ctgccaccag cgcaactacg cggaagtgtt cgggattatg gcgcaccacg tccagcgtgc
    22441 tgcaaccaat cgagccggtc gagcccagaa tggtgagttg cttcatgaaa catccagagt
    22501 tgagacagaa taaaaagcaa aacgccgcca gccgatccgc aaggatctac tgagcggcgt
    22561 ttttgtcgtt caagaaatca gaactgcatc agttctgctt ctttgtctgc cagcgccgct
    22621 tcaattttct tgattgcagc atcagtcagt ttctgtacat cgtcctgaga acggcgatcg
    22681 tcgtcttcgc tgatctcttt atctttcaac agtgctttca ctttgtcgtt cgcgtcacga
    22741 cgcacgttac gtactgcaac acgcgcttgt tctgcttcac cacgaacgat tttggtcaga
    22801 tctttacgac gttcttccgt cagcggcggc agcggaacac ggatgtcgct acccgcagag
    22861 ttcgggttca ggccaagatc ggacgccata atcgcttttt caacggccgg agacattgaa
    22921 cgatcaaaca cgttgatttt cagtgtacgg gaatcttcta ccgttacgct tgccagctga
    22981 cgcagcggcg tcggcgtgcc gtaatattcc acgacaatgc catccagcag gctgggagaa
    23041 gcacgacccg tgcgtatttt gctgatttgg gttttgaacg cttctacgca tttgtccatg
    23101 cgtacttcag catcttttct gatatcgcta atcacgttac gaatccttga aaacttgtct
    23161 cagtcagacc agacagtcac acacagtgga agtgtgctaa gtatagccct gattaaacat
    23221 attacgggta atcgtctgga ttattaggct attttatttg ccattttggc cccgggcagt
    23281 gctcgccatc ctcacgtact tttgtacgct ccggttgctg cgcgctggcc gtgaccaaac
    23341 tgcctgcaac aataacgcct tataaccaga ctaacgcccc cgcgatactt acgcggaatc
    23401 ttacccttat ttatccatca cgggaattat tccgtgatta aagtcccttc tttttcaccc
    23461 attaccacac ggcgcagcgc acccggtttg ttcatgttga aaacacgaat cggtaattta
    23521 tggtcacgag ccagcgtgaa ggccgccagg tccatgactt tcagctcttt ttccagcact
    23581 tcgctgtaag tcagttgctc gtacatggtt gcggttggat ctttcgccgg atcagcggta
    23641 aacacgccgt caactttggt tgctttcagc accacatcgg cttcaatttc gataccacgc
    23701 aggcaagctg ctgagtcggt ggtaaagaac gggttacctg taccggcgga gaggatcacc
    23761 acacggttgt tgcgcaacag gctgatagct tctgcccagc tgtagctgtc gcacacgcca
    23821 ttcaatggaa tagcggacat cagacgagcg ttcacatagg cgcggtgcag tgcatcacgc
    23881 attgccaggc cgttcattac ggtcgccagc atccccatgt ggtcgcccac aacgcggttc
    23941 atacccgctt tcgccagacc agcgccacgg aacaggttac ccccaccaat caccacacca
    24001 acctgaatac ccagttcaac cagttctttg atttcctgag ccatacgatc cagtatgctt
    24061 gcatcaatac cgaagccttc agtgccctgc agagcttcgc cactcaactt aagcagaatg
    24121 cgtttataga cgggttttgc attggtagcc atgtttcttt cctgagactg tcaacgattg
    24181 aaatgaatta atactagcga cattgtacgt cgcttttcag cgcagcccca caagggttag
    24241 ctgaatttac aagatgggca caaaaagaag ccgccctcag gcggctcctt ttcgataatt
    24301 aagactgctt ggacatcgca gcaacttctg ctgcaaagtc agtctcaact ttctcgatgc
    24361 cttcacccac ttcgaagcgg atgaagccag tcacttcagc gttatgctct ttcagcagct
    24421 gaccaacagt tttgcttggt tccataacga acggctgacc ggtcagagaa acttcgccgg
    24481 tgaatttctt catgcggcct tcaaccattt tctctgcgat ttctttcggc ttaccagact
    24541 gcatcgcgat atccagctgt acctggtatt ctttttctac cacttcagcg gatacgtctt
    24601 ctggtttgat gaattctggc ttgcttgcag caacgtgcat agcgatgtgt ttaaccagct
    24661 cttcgtcagc gcctttagca gcaaccagaa cgccgatacg cgcaccgtgc tgataagaac
    24721 ccagaacgtc gccttccagc gcagcaacgc ggcgaatgtt gatgttttca ccaattttcg
    24781 ctaccagcgc aacacgttct tcttcgaact gtgctttcag aacttcaacg tcagtgattt
    24841 tgccagcaac agctgcgtcc agaactttgt ctgcgaacgc ctggaaacca gcgtcttttg
    24901 caacgaagtc agtctggcag ttaacttcca gaatgatgcc gtagttgccg tcgattttgg
    24961 ttttgatcac gccgtcagca gcaacgttgc ctgctttttt cgctgcttta atagcaccgg
    25021 acttacgcat gttttcgatt gccagctcga tgtcgccgtt agcttcagtc agtgcttttt
    25081 tgcaatccat catgcctgcg ccagtacgct cacgcagctc ttttaccagg gatgcggtaa
    25141 tttcagccat tctaaaatcc tcggagatgt gatctgcccg gcattaaacc gcacagatat
    25201 aaaagtgaaa aagggggcca tatgcaggcc ccctaaccaa acgtgtacta cctggtctat
    25261 aagggctctc ccccttcata tttcgcgccg cagatgcgtt atcttcgctc gctcatcccg
    25321 gtcacttact gatgtaagct cccgggaatt ctcgagcttg ccgcctttct gcaactcgaa
    25381 ctattttggg ggagttatca agccttatta ctcagcttct acgaagcttt cttccgcctg
    25441 ggaagccaga tcctgagaac ggccttcacg tacggttgca gcaacagcgc ccaggtacag
    25501 ggtcacagca cggattgcgt cgtcgttacc cgggataacg aagtcaacac cgtccggatc
    25561 agagttggta tcaacgatag caaataccgg aatacccagg ttgtttgctt ctttgatagc
    25621 aatgtgttcg tggtcagcat cgattacaaa cagagcgtcc ggcagaccgc ccatgtcttt
    25681 gataccgccc aggctgtttt ccagtttctc cagctcacga gtgcgcatca gcgcttcttt
    25741 cttggtcagc ttttcgaaag taccgtcctg agactgagtt tccaggtctt tcagacgttt
    25801 gatggactga cgaacggttt tccagttagt cagcataccg cccagccagc gatggttcac
    25861 gaagaactgg tcgcagctca gagcagcgtc tttcaccgct tcgcttgcag cgcgtttagt
    25921 accaacgaaa aggattttac ctttgcgaga agcaatcttg ttcagttcag ccagagcttc
    25981 gttgaacatc ggtacagttt tctcaaggtt gatgatgtga actttgttac gcgcaccgaa
    26041 gatgaacggc ttcattttcg ggttccagta acgggtctgg tgaccgaagt gaacaccagc
    26101 cttgagcatg tcgcgcatgg aaacagttgc catgattaaa acctctatat aaaagttggg
    26161 gttatgcctc cacgtatccc atattaccga ccccaaaggg caccccggaa tatgtgccga
    26221 tacgtgtgtg ttgttacaca aagtgagatt gtcgcttccg tccagtctgt gtatacgaaa
    26281 tggatcggaa gtccggcgcg ctttatacca caaatacgtc atggacacca ataattgttg
    26341 gcgctgtgta cagcatcaga tgtcgaattt tctattatag aaaaccttca gtggcacgtt
    26401 tggcgaaatt cagaatgatt ctcaatttgc ccgggtgtga taccattgac ggcacttaca
    26461 tatatattgt cggtatcacc gacgctgatg gacagaatta atggctatct caatcaagac
    26521 cccagaagat atcgaaaaaa tgcgcgtcgc tggccgactg gctgccgaag tgctggagat
    26581 gatcgaaccg tatgttaaac cgggcgtcag caccggcgag ctggatcgca tctgtaatga
    26641 ttacattgtt aatgaacaac acgcggtttc tgcctgcctc ggctatcacg gctatccgaa
    26701 atccgtttgc atctctatta atgaagtggt gtgccacggt atcccggacg atgctaagct
    26761 gctgaaagat ggcgatatcg ttaacattga tgtcaccgta atcaaagatg gtttccacgg
    26821 cgatacctcg aaaatgttta tcgtcggtaa gccgaccatc atgggcgaac gtctgtgccg
    26881 catcacgcaa gaaagcctgt acctggcgct gcgcatggtc aaaccaggca ttaacctgcg
    26941 cgaaatcggt gcggcgattc agaagtttgt cgaagcagaa ggcttctccg tcgttcgtga
    27001 atattgtgga cacggtattg gtcgcggctt ccatgaagaa ccgcaggtgc tgcactatga
    27061 ctcccgtgaa accaacgtcg tgctgaaacc ggggatgacg ttcaccattg agccaatggt
    27121 caacgcgggt aaaaaagaga tccgcaccat gaaagatggc tggacggtaa aaaccaaaga
    27181 tcgcagcttg tctgcacaat atgagcatac tattgtggtg actgataacg gctgcgaaat
    27241 tttgacgcta cgcaaggatg acaccatccc ggcgataatc tcgcacgacg aataagatga
    27301 agccggcgaa tgccggcttt tttaatgcga taatttaatc ttatgggtgg cgcacaatga
    27361 atacccttcc agaacagtac gcaaacaccg ctctccccac cctgcccggt caaccgcaaa
    27421 atccatgcgt ctggccccgt gatgaattaa ccgtcggtgg gataaaagcc catatcgata
    27481 ctttccagcg ttggctgggt gatgcctttg acaatgggat ctctgcagaa cagttgattg
    27541 aggcgcgcac cgagtttatc gaccagctcc tgcaacgatt atggattgaa gcgggattca
    27601 gccagattgc cgacctggca ttggtcgccg tcggtggcta cggtcgtggc gagctgcatc
    27661 cactttctga catcgattta ctgattttaa gccgtaaaaa gctcccggac gatcaggcgc
    27721 aaaaagtggg cgagctgtta acgctgctct gggatgtaaa gctggaagtc ggtcatagtg
    27781 tgcgcacgct tgaagagtgc atgctggaag ggttatcgga tttaaccgtc gccaccaatt
    27841 taatcgaatc ccgcttatta attggcgatg ttgcgctctt cctcgaactg caaaaacata
    27901 tttttagcga aggattctgg ccttccgaca agttctacgc ggcgaaagtt gaagaacaga
    27961 accagcgcca tcagcgttac cacggcacca gctacaatct tgaaccagac atcaaaagta
    28021 gccctggcgg cttgcgcgat atccacactc tgcaatgggt ggcccgccgt cattttggcg
    28081 caacatcgct ggatgaaatg gttgggtttg gcttcttaac ctcagcggag cgggcggaat
    28141 taaacgaatg tctgcatata ctgtggcgta ttcgctttgc cctgcatctg gtcgtcagcc
    28201 gttacgataa tcgtctgtta ttcgatcgcc aacttagcgt cgctcagcgt ctgaattaca
    28261 gtggtgaagg caacgaaccg gtcgagcgga tgatgaagga ttacttccgc gttacacgcc
    28321 gcgtcagtga actcaaccag atgctgctgc aactgttcga tgaagccatc ctcgcccttc
    28381 ccgccgacga aaaaccacgt ccaatcgacg atgagtttca gctacgcggt acgctaatcg
    28441 acctgcgtga tgaaacacta tttatgcgcc agccggaagc catcttgcgt atgttctaca
    28501 ccatggtgcg caacagtgcg atcaccggca tttactccac cacgctgcgc cagttacgcc
    28561 atgcccgtcg ccatctgcaa caaccgctgt gtaatattcc ggaagcacga aaactgtttt
    28621 tgagcattct gcgtcacccc ggagcggtgc ggcgcgggct attgccaatg catcgccata
    28681 gcgtgctcgg cgcgtatatg ccgcaatggt cgcatatcgt cgggcagatg cagtttgatc
    28741 tgttccacgc ctacacggtg gatgaacata ctatccgcgt gatgctgaaa ctggagagtt
    28801 ttgccagtga agaaacgcgc cagcgccatc cgttgtgtgt ggacgtctgg ccgcgcctgc
    28861 cgtcaactga gctgattttc atcgccgcgc tgtttcacga tatcgccaaa ggacgcggcg
    28921 gcgaccactc cattctcggt gctcaggatg tagtgcattt tgcagaactc cacgggctga
    28981 actcacgcga aacacagctg gttgcctggc tggttcgcca gcacttgctg atgtcggtga
    29041 cagcacaacg ccgcgatatt caggaccctg aagtcatcaa gcagtttgcc gaagaagttc
    29101 aaacggaaaa tcgtctgcgc tatctggtat gcctgacagt ggctgacatt tgcgccacca
    29161 acgaaacgct gtggaatagc tggaagcaaa gtctgttgcg cgaactctat tttgccaccg
    29221 aaaagcagct acgacgcgga atgcaaaaca cgccggatat gcgcgaacgg gttcgccatc
    29281 accaactcca ggcactggca ctactgcgca tggataacat cgacgaagag gcgctgcacc
    29341 aaatttggtc acgctgtcgt gctaactatt ttgtccgcca tagcccaaat caactggcct
    29401 ggcatgcccg ccatttatta cagcatgatt taagcaaacc gctggtattg cttagcccgc
    29461 aggctacgcg tggaggcacc gagattttta tctggagccc ggaccgcccc tatctgtttg
    29521 ccgccgtctg tgccgaatta gaccgccgca atttaagtgt tcacgacgca caaattttca
    29581 ccactcgcga cggtatggcg atggatacct ttatcgtgct ggaacccgat ggcagcccgc
    29641 tgtccgcaga tcgtcatgag gttattcggt ttggtctgga gcaagtactg acgcaaagta
    29701 gctggcagcc accgcagccc cgtcgccaac ccgccaaatt acgccatttt actgttgaaa
    29761 ccgaagtaac gtttttgccg acccataccg accgcaaatc gttccttgag cttatcgcgc
    29821 tcgaccagcc aggactgctg gcgagagtcg ggaaaatttt tgccgatctg ggaatttcgc
    29881 ttcatggtgc ccgaattaca accattggcg agcgagtaga agatttattc ataattgcca
    29941 ccgctgaccg gcgtgcactt aataacgagt tgcagcagga agtgcatcag cggttgacag
    30001 aggccctcaa tccaaacgat aaagggtgat gtgtttactg atatgaaaag agtttaacaa
    30061 tgcagcagtt acagaacatt attgaaaccg cttttgaacg ccgtgccgag atcacgccag
    30121 ccaacgcaga caccgttacc cgcgaagcgg taaatcaggt gatcgccctg ctggattccg
    30181 gtgcactgcg tgtagcggaa aaaattgacg gtcagtgggt gacgcatcag tggttgaaaa
    30241 aagcggtgct gctctctttc cgtattaatg ataatcaggt gatcgaaggg gcagaaagcc
    30301 gctacttcga caaagtgccg atgaaattcg ccgactacga cgaagcacgt ttccagaaag
    30361 aaggcttccg cgttgtgcca ccagcggcgg tacgtcaggg tgcatttatt gcccgtaaca
    30421 ccgtgctgat gccgtcttac gtcaacatcg gcgcatatgt tgatgaaggc acgatggttg
    30481 atacctgggc gaccgtcggt tcttgtgcgc agattggtaa aaacgtccac ctttccggtg
    30541 gcgtgggcat cggcggcgtg ctggagccgc tgcaggctaa cccgaccatt attgaagata
    30601 actgcttcat tggcgcacgc tccgaagtgg ttgaaggggt gattgtcgaa gaaggttccg
    30661 tcatctctat gggcgtatac attggtcaga gcacccgtat ttacgaccgt gaaaccggcg
    30721 aaatccacta cggtcgcgtt ccggcggggt ctgtggttgt ttcaggtaat ctgccgtcga
    30781 aagatggcaa atacagcctc tactgtgcgg ttatcgttaa gaaagttgac gcgaaaactc
    30841 gcggcaaagt cggcattaac gaactgctgc gtaccatcga ttaagagtac atatacgggc
    30901 agcataatgc tgcccgtatg ctttctggct cagaataatt cgacctactc attcttcccc
    30961 ccttttttaa atactttttc atcttgtttc ggactgtcat gtaattcgca aaacgaagat
    31021 aaatgtgcta atccatccca tggaatatcg ccacaataaa gcaggtaatt ttttgatttt
    31081 tacgccatga tagaagtctg gaagaaaaag gctttctgcg atcacagtcg agccgggcgg
    31141 gccaggccaa atgctaaaat aagcacaatt tactgactca ttttgaggta acgctatgta
    31201 cgacaatctg aaaagtctgg gtattaccaa tcctgaagaa attgatcgtt acagcctccg
    31261 gcaggaagcc aacaacgata ttctgaaaat ctatttccag aaagacaaag gcgagttttt
    31321 cgccaagagc gttaagttta aatatccgcg tcagcgtaaa acggtcgtcg ctgatggtgt
    31381 gggtcagggt tataaagaag tccaggaaat cagcccgaat ctacggtata tcattgatga
    31441 gcttgatcaa atctgccagc gtgaccgcag cgaagttgat cttaagcgta agatcctcga
    31501 cgacttacgt cacctggagt cagtcgtaac caataagatc agcgagattg aagccgatct
    31561 ggaaaaacta acgcgtaaat aatgccgaac tgacggttaa ctcggacatt cccctctacc
    31621 cttcgggctg aggggaatga gccagcgccg cctcgacctt aacgcataac ctaccgctct
    31681 tcatccagct gcaacgccac atacagcagc aacctgtcat caaaattacc caaatcaagc
    31741 tcggtcagtt ccgatatacg attaagccga tactccagag tattacgatg aataaacaac
    31801 gcctttgacg ttgccagcgg ttgcacattg tgacgaaacc acgccgccag cgttcgtcgc
    31861 agcaagccgt tattgtccat cgctttcagc cgcgccagcg gtcgcgccag ttcgttggcc
    31921 tgccagtcgc cacgcaaact gtcgagtaac acaggtaaca tcagatcctg ataaaaatag
    31981 cagcgacttt ctggcatccg ctgtttaccc accaccatcg tcgttttcgc cgtacgatag
    32041 gatcgggcaa tactgccagg accggtaaaa tagttgccca gtgaaacgcg aaaacgcagc
    32101 tggccgtact ctttcatgcg ggtaatcagt tgttcaactc gcttacgatg atcttctgca
    32161 tcccagcgcc caaaagagtt caacgccggt ttcaacacca ccatttcggt tagcgagaca
    32221 atcgccacca gattattacg ctcgggcgta gtcagcgcgt tttgcagttg ttgtaactcc
    32281 gccattgcgc tgtccacacc aagctgaccg ctgtcgacct caacaatagc caccactcgc
    32341 ggttgattga gatcgatccc cagccgttgc gcccattcag taagtgcggg agtattctcc
    32401 tctgcctgaa tcaggttcat caccagttcc tcccgcaaac ggctatcctg agccaacaag
    32461 tgcatcaacc gcgactgttc cagcatcatt tcagccgtca tgcagaccag ttcgccatat
    32521 ttacgcagat tctctggttc acctgtcagg ccaattacgc cgacaatttc accttccagc
    32581 cgtaacggta gattaatccc ttgccgcaca ccgtgcagat gacgtgccac cgcgtcatcg
    32641 atatcgacga ctcgtccctg tgaaagtacc agcaatgcac cttcgtgcaa ttcaccaata
    32701 cgctcacgat cgccgctgcc gataattcgc ccacgggcat ccattacgtt gatattggta
    32761 tcgatgatgc gcatggtacg tgccacgata tcctgcgcca ttttggtatc aagatgccag
    32821 ccagccataa gtcctccgtt atgcacggct tagcataagg aagtacgtaa cgtacggcat
    32881 tgtgcaaatg cctaaaggat gatgaagatg tatggagttg tggtgaagtt cacagattgt
    32941 aaggagaacc ccttcccgtt ttcaggaagg ggttgaggga gattactgca ttaacaggta
    33001 gatggagctg tcgccgcgct gaatgttcag tgccagcaca gacggtttgc tgtcgagaac
    33061 tttacgcagt tcagcgatgt ttttcactgc ctgctggttc gcgccaataa tcacatcacc
    33121 tttcttcagg ccgatctgcg cagccggagt gcccgttttc acgttgttca ctaccacgcc
    33181 ctgatctttg cctttgttgc tcatctcagc accttcaatg ccgttgaaga tggagctgga
    33241 atcaacctga ttctggctgc tctgctgcag ttccagattc acgttgacct gcttaccgtc
    33301 gcgcagcaag cccagggtca gtttgctgcc caccggcata gtacccacct gagcacgcag
    33361 tgcggcaaag ctgctgattg gcttaccgtt cagtgaggtg atcacatcac ccgctttaat
    33421 gcccgctttt gcagcggagg aattaggcag aacctggctt acgaaagcac cgcgctgggc
    33481 gtcaactttc atcgctttcg ccagttcgga attcagctca gtccccataa tacccagctc
    33541 accgcgtttc acctggccgt attccaccat ctgcgaggtc aggtttttca ccatgttgct
    33601 cgggatagca aaaccgatac cgatgttgcc gccgtccggt gcgaggatcg cggtgttgat
    33661 accgatcagt tcgccgttca ggttaaccag cgcaccaccg gagttaccac ggttgatcgc
    33721 tgcatcggtc tggatgaagt tttcgtagtt ttcggcattc aggccgctac gccccagcgc
    33781 agagacaatc ccggaagtta ccgtctctcc caggccaaac gggttaccaa tcgctacggt
    33841 gtaatcaccc acgcgcagtg catcagaatc cgccatctta attgcggtca ggtttttcgg
    33901 gttctggatc tgaatcagcg cgatatcaga gcgcggatct ttgccaacca tcttcgcgtc
    33961 gaacttacga ccatcgctca gttggacttt aatcaccgtc gcgttatcaa caacgtggtt
    34021 gttggtgacg acatagcctt tatcggcatc aatgatgacg ccggaaccca gcgccatgaa
    34081 tttctgttgc tggccgccgc cattaccgcc ctggcccccc tggcagaacg gagagctctg
    34141 gaacggtgaa ccttcctggc agaacggaga atcatcaccg aagaactgct ggaaattacg
    34201 cggcatacgc ggcgtattaa cggttgtgct accttctacg ttaatgctga ccactgaagg
    34261 catcaccttt tcgagcatcg gtgcaaggct tggcatctgc tgggctgtcg ttgctgaaga
    34321 agtctcagcc gccgttgcag agagcggaga taacgccaaa cctaaactca gagccagtgc
    34381 actcagtgct aatgtggttt ttttcatgta tttcagtctc gattaacaga taacgcaaaa
    34441 ttgctgtgtt cttcagattc gttttatagc gcgaagttcc gaactaaagt ttctgcaaaa
    34501 ggtaaaaatt tattgttcgt ctttacaaaa gcctggttat tgttctacgg ccatcagacg
    34561 tcggtattca tcccacgcat agaggtcggt cataccgctg atataatcct gcagcaggcg
    34621 gcaacggtaa taatattccc atagcggaaa ctcaggagaa tctgacggta atttactgac
    34681 agcctcgaca taggccagcc gatggcgcgt cgagagtttg tggaataagc gcgattcaat
    34741 agggaaacgt ttcacccgtt ctttttctac cagttcagta aagtctgata acgacaggct
    34801 taataaagga cgataaatct ctaataatcc gctaatgacc cgatagccct gcaattcaag
    34861 ctgctcgaca tccggatggc taaacacatg ttttacagcg acatttttat atagcttaag
    34921 aagatcgctg cattcgctgg catcttccaa taatgcatga ttaaacgttc cggcgaaaat
    34981 cgcaggcaga ttatcaataa atcgttgtgc cgcgtatggt accagtttat ttagggtgtt
    35041 tacccgtaaa tacataaaaa actgatcttc cgtactgcgg cttaaactat ttgagcgtga
    35101 tttttcccag gcattttcaa ccactagcga aaagagcgaa cctttctcat gctgacccca
    35161 cgcctcgtgc aaatgatgat aaagctgctc aacggtaaat attcttttct ctaccgcatc
    35221 ttcaaggtct gccacacaat aggagatgtc gtcggcagct tccataatcc acgttaatgg
    35281 aaaacgactg taaagcgcca aattaagttc tttacgcaac cgggcaatat aggcttcttc
    35341 agaaagataa taacccggct ttttcattaa atagtgatgt gtctcaggcg tttcgccacg
    35401 ccaccacgcc ggacgggtat attttaaaat accgccaacc tgtgcccagg tgagattcat
    35461 cctcatcaat gtatgcacca gacgaatgcc ttgtgcattc ccctcaaaat gacataagtc
    35521 ctgacgaatc ttgcgccgca actcgttaag cggttcttcc ccgtcccgta aacgtagtgc
    35581 cgccacgctg cagcgatcgt cagtcagagg ctggctttcg gcatcttccg ggtataaacg
    35641 ctggcgaaac cagtcattta tcgccgcttc gccaaaatga ccaaacggcg gattgccgat
    35701 atcgtgcatc aggcatgaca tctcaacaat gctttcaaaa ggtccggtca gttcatccag
    35761 gccgtatgct tccagcaatt taagctcttt cagacggctt aaaatttctt tggcgatgta
    35821 gcgccccacc tgctggactt ccatcgagtg ggtaagacgc gtgcgcacgg cggcattgcg
    35881 ctccagtgga aaaacctggg tcttttgttg cagacgacga attgccggag agttgatgat
    35941 acgcccgcga tcgctctcga agatccgcag gatctcatgt tcggttttaa cgccctgcgg
    36001 tgaacggtaa cgacgatgcc agtttatttt ttttcggaaa tcaatctgtg ccatgtcctc
    36061 tcccgcgtga gaaatacgct tccccgtaag cgcatggtaa actatgcctt caaatcgggc
    36121 ttatcgcgag taaatctatg aaaatcggca tcattggtgc aatggaagaa gaagttacgc
    36181 tgctgcgtga caaaatcgaa aaccgtcaaa ctatcagtct cggcggttgc gaaatctata
    36241 ccggccaact gaatggaacc gaggttgcgc ttctgaaatc gggcatcggt aaagtcgctg
    36301 cggcgctggg tgccactctg ctgttggaac actgcaagcc agatgtgatt attaacaccg
    36361 gttctgccgg tggcctggca ccaacgttga aagtgggcga tatcgttgtc tcggacgaag
    36421 cacgttatca cgacgcggat gtcacggcat ttggttatga atacggtcag ttaccaggct
    36481 gtccggcagg ctttaaagct gacgataaac tgatcgctgc cgctgaggcc tgcattgccg
    36541 aactgaatct taacgctgta cgtggcctga ttgttagcgg cgacgctttc atcaacggtt
    36601 ctgttggtct ggcgaaaatc cgccacaact tcccacaggc cattgctgta gagatggaag
    36661 cgacggcaat cgcccatgtc tgccacaatt tcaacgtccc gtttgttgtc gtacgcgcca
    36721 tctccgacgt ggccgatcaa cagtctcatc ttagcttcga tgagttcctg gctgttgccg
    36781 ctaaacagtc cagcctgatg gttgagtcac tggtgcagaa acttgcacat ggctaagtca
    36841 ctgttcaggg cgctggtcgc cctgtctttt cttgcgccac tgtggctcaa cgccgcgccg
    36901 cgcgtcatca cgctttctcc cgccaacact gaacttgcct ttgctgccgg gatcacgccg
    36961 gttggggtca gcagctattc cgactatcct ccacaagcgc aaaagattga gcaggtttcc
    37021 acctggcagg ggatgaatct ggaacgcatt gtcgcgctga agcccgatct ggtgattgcc
    37081 tggcgtggag gtaatgccga gcggcaggtt gaccagctgg cttcgctggg aataaaagtg
    37141 atgtgggtcg atgcgacaag cattgaacaa attgccaatg cgttacgtca actggccccc
    37201 tggagtccgc aaccagacaa ggccgaacaa gccgcgcaat ccctgctgga tcagtacgcg
    37261 caattgaaag cgcaatatgc tgataaacct aaaaaacgtg tttttctgca attcggcatt
    37321 aatccgccat ttaccagtgg aaaagagtcg attcagaacc aggtactcga agtttgtggc
    37381 ggagaaaaca tctttaaaga cagccgggtt ccctggccgc aagttagccg cgaacaggtg
    37441 ttagcacgct cgccacaggc gattgtcatt acaggcggac cggaccaaat tcctaaaatc
    37501 aaacaatact ggggtgaaca gctcaaaatt cccgttattc ctctcacgag tgactggttt
    37561 gaacgtgcaa gcccacgtat tatcctcgct gcacaacagc tctgtaatgc gctttcacag
    37621 gtagattagc gcctgacctt ttcaggtgct cagtggggat tgaacaatgc tcgtctattg
    37681 gctggatata gtcggcacag cggtatttgc catctccggc gttttgttag ccggaaaatt
    37741 gcgtatggac ccttttggtg ttctggtact gggcgtggta accgcagtag gcggcgggac
    37801 aattcgcgac atggcgctgg atcacggccc ggtattttgg gtgaaagatc ccaccgatct
    37861 ggtcgttgca atggtcacca gcatgctgac catcgtgctg gtgcgccagc caagacgctt
    37921 accaaaatgg atgttgccgg tgctggacgc cgttggtctg gcggtgtttg tcggcattgg
    37981 cgtgaataaa gcctttaatg cggaagccgg tccgttaatc gcggtttgca tgggcgtcat
    38041 tactggcgtt ggcggcggga tcattcgtga tgtactggcc cgcgagatcc ccatgatttt
    38101 acgtacagaa atctacgcaa ctgcctgtat tatcggcggt attgtccacg ctacggctta
    38161 ttacacattt tccgtaccac tggaaacagc cagtatgatg ggcatggtcg tgacgctatt
    38221 gattcggctg gcggctattc gttggcatct taagctaccg acgtttgcgc tggatgagaa
    38281 tgggcgttga agagagaaga tgtgccggat agtttatccg gcacatgaac aacagattag
    38341 atgctaaagg aagaaccgca accgcaggtg cttttcgcgt tcgggttggt cacgatgaaa
    38401 cgagaacctt ccagaccttc ggtataatca acggaaccgc cgaccagata ttgcaggctc
    38461 atcggatcaa ccaccaggcc aacgccctgt ttttcgatgg tcatatcgcc ttcgttcacc
    38521 tgatcatcaa aggtgaaacc atactggaag ccgctgcaac cgccaccggt gatatacacg
    38581 cgtaatttca gattcgggtt atcttcgtca gcgatcaggc ttttaacttt gttggctgct
    38641 gcgtcggtaa actccagcgg cagtgctacg tcatcactca tattttgctc caaacgacat
    38701 cggcaattgg gcaaattcta acccaataat aatcgccatt atctaatacc ctggtatttc
    38761 gttcaagtat tctcgctggc tgatgcggcc ttgcttcgcg ccagttgctc agcttcctgt
    38821 tttgccagcg tgcgcgcaag aatcgccgag tatagcggtt tcccgccggt aaattgcgct
    38881 aatagtgttg cgccaagacc ggtaataatc attggcaaaa tgagctggta gttatcggtc
    38941 atctccagaa ccagaatgat ccccgttaac ggcgcgcgaa tagatgccgc cagtaatgcc
    39001 cccattccgg caatagcaaa cgtccccgcc tccaggtgat attgcggaaa cagctcaacg
    39061 gcaaccattc cgaaagcggt tcccagcaca gtacccagcg ccagcatcgg ggcaaaaata
    39121 ccgcccggcg cgccggaaga gaagcagagt aaggtggtaa tgacccgagc gacgaagata
    39181 aacaccagca ttcccatgct gaaattcccc gcggtagcga taggaatcag gttaaaaccg
    39241 ccgcccgacg ttgctggtgc cacaaacccc agcaatccac acagaccgcc aatcgcacca
    39301 cccatcagta cccatttggt aatattgccg ccgtgcacac ggtgcagcaa atcctgcatc
    39361 cccagcaccc atttattaaa aatagggccg aaaatgccaa aaataatacc gaggatcaga
    39421 taaagccaca gcgtattaag cggcgcatca gaaagtttac cgacgtcaat caacgcaact
    39481 tcatgattaa aaatccggta cataatggtc gacataatga cgccaataaa taccgcttta
    39541 atcgaaatta acgtatagcg aaactgcgga cgcatctctt cgataataaa caaaataccc
    39601 gccagcggcg cgttaaaggc cgcagccagc cccgcagcag caccggttgc cagcagcgta
    39661 tggcgagctt catcaccttt caggcggaaa atatcaagca ccatgcgacc gatattgccg
    39721 ccgatctgca cggttggtcc ttcgcgccct agcaccatgc ctccgccgag tgtccccagc
    39781 ccgccaaaga atttcaccgg caatacacgc caccagcgaa caggacgttg atcttccagc
    39841 gccccttcaa tttccgggat ccccgatccc cctgcttcgg gcgcgtattt gcgcaccaaa
    39901 aagtagccga acatcgccag caccgccgaa cagagaaaag cgacggttaa cagtagcgga
    39961 taattatcag cagtatgtac cagcgccccc atacgttggt tctgcaacca ggcgacacct
    40021 ttgtcaaaag caaccgctgc cagcccgaca agcgtgccga cgactgccgc cataaacaaa
    40081 atggctaacg gggttttatc gcgctcaaga agttggcgaa tcagttgtct acgtcgcagg
    40141 cgcgcggcct gcggtgtttc taaagaggga gtatcagttt tcatccaatg atcacttatt
    40201 ggtcatacaa ataagatgac ggcattttac tcgcacgttc catgaaaatc ctttgcaaag
    40261 cgtaatgttt caaatgcaca aaacttttat actctaagaa atcaggattg caccagtaca
    40321 agcagcctga tgtttgacga gtatttaact tgttatgaat aacatagaat agcagccatt
    40381 cactttttct acgaatcagg aaccctccat gagtaagtct gaaaatcttt acagcgcagc
    40441 gcgcgagctg atccctggcg gtgtgaactc ccctgttcgc gcctttactg gcgtgggcgg
    40501 cactccactg tttatcgaaa aagcggacgg cgcctatctg tacgatgttg atggcaaagc
    40561 ctatatcgat tatgtcggtt cctgggggcc gatggtgctg ggccataacc atccggcgat
    40621 ccgcaatgcc gtgattgaag ccgccgagcg tggtttaagc tttggtgcac caaccgaaat
    40681 ggaagtgaaa atggcgcaac tggtgaccga actggtcccg accatggata tggtgcgcat
    40741 ggtgaactcc ggcactgaag cgaccatgag cgccatccgc ctggcccgtg gttttaccgg
    40801 tcgcgacaaa atcattaaat ttgaaggttg ttaccacggt cacgctgact gcctgctggt
    40861 gaaagccggt tctggcgcac tcacgttagg ccagccaaac tcgccgggtg ttccggcaga
    40921 tttcgccaaa cataccttaa cctgtactta taacgatctg gcttctgtac gcgccgcgtt
    40981 tgagcaatac ccgcaagaga ttgcctgtat tatcgtcgag ccggtggcag gcaatatgaa
    41041 ctgcgttcca ccgctgccag agttcctgcc aggtctgcgc gcgctgtgcg acgaatttgg
    41101 cgcattgctg atcatcgatg aagtaatgac tggcttccgc gtagcgctag ctggcgcaca
    41161 ggattattac ggtgtggaac cggatctcac ctgcctgggc aaaatcatcg gcggtggaat
    41221 gccggtaggc gcattcggtg gtcgtcgtga tgtaatggat gcgctggccc cgacgggtcc
    41281 ggtctatcag gcgggtacgc tttccggtaa cccaattgcg atggcagcgg gtttcgcctg
    41341 tctgaatgaa gtcgcgcaac cgggcgttca cgaaacgttg gatgagctga catcacgtct
    41401 ggcagaaggt ctgctggaag cggcagaaga agccggaatt ccgctggtcg ttaaccacgt
    41461 tggcggcatg ttcggtattt tctttaccga cgccgagtcc gtgacgtgct atcaggatgt
    41521 gatggcctgt gacgtggaac gctttaagcg tttcttccat atgatgctgg atgaaggtgt
    41581 ttacctggca ccgtcagcgt ttgaagcggg ctttatgtcc gtggcgcaca gcatggaaga
    41641 tatcaataac accatcgatg ctgcacgtcg ggtgtttgcg aagttgtgat gattttgcct
    41701 cgcccaccgg gcgaggcatt caattaacgg ctctgctttc tcaacaaata gataaaatat
    41761 ggcgcgccga taaaggttga cagcagcccc gccgggatct ggaatggaaa cagcaccatc
    41821 cgcccacacc agtcagcgaa caccagcagt aaacccccca ccagcgccga aattacgatg
    41881 tgtggcatcg tccgtcgaaa gcccatcatc cgcgcaatat gcggtgccat taaaccaaca
    41941 aaactcaacg gtccaatagt catcgtcgcg gtcgccgtca ggcaagccgc taacagcagc
    42001 agcgcaattc gcgtcggcgt cagcgccatt cctacggctc gggcggtatc accacccagc
    42061 ggtaaaatgg tcagccagcg gcggcacagc ggggtaatcg ccagcaaaat caccatcaca
    42121 attccggtgc gccagacctg cgcatcggtc gcgttgtagg tcgaaccgga aatccaggtc
    42181 agcacttgcg ccattcgcgg gtcaccactt gcctgcaaca tcatcaaaag catggtgaac
    42241 gcggtactta acgccatccc cgccagtaac atgcggtgtg gggaaaatcc accgcgtccg
    42301 gcggcgatca taatgatcaa cagcgtcacc gccgccccga gactgcctgc gggtaacagc
    42361 cagccaaagg cattacccgg taccagaaac agcattaaca ccacaccaaa cgccgcgccg
    42421 gagctaatcc ccagcacttc cgggcttgcc atcgggttgc cggtcagccg ctgaataata
    42481 cagcccgcta ccgccagcat gacgcccgca aacagcgccg ccataattcg cggccagcgc
    42541 cagggcatta aatcatcgag cagcgccccg ctcgcccacg tccagccgtg cgcatcacga
    42601 ccaaacgaca gcgccaccac cacagccatc aacagcagca cgccgcccgc gagggcaaac
    42661 gccagcacat gttggcgttc agtcgcgaca cgatcgttaa ccttcatatc cggcgcgcta
    42721 atgctgcgta aacgcggcag cagccacagt agcagcggcg caccgatcaa cgcagtgacc
    42781 gaaccggtgg aaacttccat ccacacgcga gtcagccaga ggatgatttg atcagaaagc
    42841 cacagaatta acgcaccaat cagcgacgcc agcatcaacc gtggcaacaa acgccgcgcc
    42901 cccagcattt ttgccagcag tggcgcgaac aacccgataa agccgataat ccccactgcg
    42961 ttcaccagca gcgcactgat gactatcgcc agcgacagcg ccgccagacg cgcgagcgac
    43021 aaggccagcc cgagattgcg cgccacgcca tcatcaagcc ccatcagggt taacggacga
    43081 agtagcagta acgtcagcat cacgccgccc agcaactgcg gccataaacg ctcaacgccg
    43141 ccccagtcgg tttgcgtcag cgttccggtg ctccacagga acatgctttg caactggtca
    43201 tgatggaaga taaccagtaa ctgattgatt gccccacaat aaaggctcac taccagcccc
    43261 gcgagaatca gcgttaccgg cgacagccgt ttcccccacg cgacgccaaa gacaattaag
    43321 ccaacaacgc aagcccctgc cagcgcagca aactggctcg ccatagcacc tgggatcgcc
    43381 cagagcgtgg tgacggtaat ccccagttgc gcgcctgtag caacgcccaa cgtcgtcggt
    43441 tccgccagcg ggttacgcag cacttgctga aacagcacgc ccaccagccc caggcccgcg
    43501 cccaccagta gagaaatcgc cagacgtggt aacaagctgt agtgaaaaat catctgctcg
    43561 atgacgttaa tatccggcga ccaggcggcc tgcgcccact ggctacgcgg cagcgcctgc
    43621 gaaaagttca tccaggtcag cgccgtagcg acaatcacca gcagcgccag caataacgcc
    43681 ggaaaaagcg caattcgttt actcacgctt tacctccgat ggcgttatcc agaacgcgca
    43741 caaagtgcat tgccgagagc gtcgcaccat aaaaccagac tgcgggtacg cgctgaaagc
    43801 gtccggcgcg gacaaacggc atggcctgcc acagcggggt tgccattagc gcgtccatgt
    43861 ctttgctgtt gtcgtgatca aaacagagca catcaacatc tttatacgcc gccagacgat
    43921 cgatgctgac ggcggtactg ccccagaagt tggtttcccc ttgccaggca tttgggatgc
    43981 cgtactcatc aagaatttcc tgaaacaagc tgtttggacc gaaaaccagc atatggcgcg
    44041 gatcgataag cgtcgtcagc aataacgggc gttcaccacg cttcacaaag cggggtttca
    44101 tgctgcggat aaagtcttca tagtgcgcta aatgcgtttc tgctgcgctt tgcaggttaa
    44161 gtaaatctgc catttccgtc agtgacttac gcgccatcgc cagcggctgt ttgccgtcgc
    44221 tgaagttaaa tccacgcccc ggcgcaatac gagccagcat ttctggtgaa gggccatatc
    44281 ctgccgacca gaccataaac gatggtttca tttcggtcag cagttcaagg ttaggttctg
    44341 tgcgcaaacc gacgtcgatc actgagtccg gcaatggtgg ttcgctgacc cacaggcgat
    44401 agttgatggt atccgccacg ccgtaaggca cgatgccgag cgccagcagt aattccaccg
    44461 gcaaccactc cagcgccaca atacgattgg gatcaatagc cgccgcgtgg gcggtattca
    44521 tctgccataa caacggagaa agcgccatcg ccgttaacag tcgacggcgc gaaataagag
    44581 gtaagccgct catcaataaa caaaactcac aggtgcagca cccgccggat gcggcaaaat
    44641 acccatcggg atgccataaa tcatttcgag ggtttcgccg cgcataattt ccgcaggcgt
    44701 tccctgaaca atcatttcac cgccgcgcag ggcgaccaga taatcacagt agcgtgccgc
    44761 catattgata tcgtgcaaca cggcaatgac cgtcaggcca cgctcctgac ttaaacggtg
    44821 caccagcgac agcacatcaa cctggtgggc gatatccagc gccgaggtcg gttcgtcgag
    44881 caacagacaa cggctatcct gcgccaccag catggcgatc cacgcccgct gacgttcgcc
    44941 gccagagaga ctatcgacca gccgatgcgc cagcggtttt aagccaacca gcgagatagc
    45001 ttcctcgacc ttttcgcgat ctgccgcacc aaagcgcccc agcgcgccat gccacgggta
    45061 acgaccaatc gccaccagtt cacgcacggt catcccttct gccggaggaa gctgctgcgg
    45121 caaataagcc actttgcggg caaacgcttt gctgctccag ctttccagcg gctgggcatc
    45181 aagaagaatc tccccttctg acggaggctg atgacggcca agcattttga gcagagtgga
    45241 tttaccagaa ccgttgtgac caatcagacc ggtcactttc ccggcaggaa aggttaacga
    45301 cagcggatgc aaaagcgtgc gcccgggcac acgaaaggag atattacgca gtgcaaaagt
    45361 ggtatcggaa tgattcgtgt attcctgcat aacagccaac ttgtgaaatg ggcacggaaa
    45421 tccgtgcccc aaaagagaaa ttagaaacgg aaggttgcgg ttgcaacgac ctgacgttct
    45481 gcgccccaga agcagccata agtgttaaag cagctggcga cgtattcacg atcgaacagg
    45541 ttgttaacat gcagcgccac gttggagccc gccatgccga ctcgcgccag atcataacgc
    45601 actaacgcat ccacgaccgt ataacttccc actttaaagg agttagccgg atcaccatag
    45661 ctggagccag tataacgacc accggtgccc agcgtcagac ctgaaagcgg accgtcaaag
    45721 aaggtatagt cagcccacag cgaagccatg tgttttggca cctgtgcagg cgtattgcct
    45781 ttataggtag tatcggtggt gtattccgca tcggtgtaag tataagaacc gactacgtta
    45841 acactcgccg acagcgccgc tttcgcttcg atttctacgc cacgtgcgcg gatctcgcca
    45901 ccttcaaccg agaagaagga accctcaggg tccgccatca ggttgttggt tttagtgaga
    45961 ttatacacgg caccagtaac tacaatcgga cgatcttccg gtacatattt cacgccgact
    46021 tcatactgct tacctttaga cggtgcgaaa atattaccat ccttcccaac ttgcgaagaa
    46081 ggttcaaacg attcgctata gctgaagtaa ggtgttacac cattatcaaa caggtagtta
    46141 acaccaccac gccaggtaaa ctgtttgtca tcacgtttat cggtcgtccc agcaacgcgg
    46201 ttaagagatt cttgatctgc ccagtcataa cgaccgccca gggtgaccag cactttatcc
    46261 cactgcgcct gatcctgaac ataaacgccc gtttgtttct gcttattcag aatgcggtaa
    46321 gggccggagt ttgccggatc tttggcattg aagtcgaaat cggtattcac cggattgtac
    46381 agattgagca gtggcacaga gtcgtcgtaa ccaaaccagg cgttgatgtc attacgcata
    46441 cgcataaagt cgacaccggt cagcagggtg tggtcgatat cgccagtggc aaacttgctc
    46501 tgcaactggg tatcaacgga gaagttttgc agcttctcat catcaacgac gtatttacgt
    46561 gccagataat ggcctttatc cgctggcgct aatgccgcac actgtttgct gtaagcattc
    46621 gccggatcgg agcagacgcc gtaaccataa acgctgtttt gcgaggtttt gttttcagca
    46681 aagcgcaggt tctgacgcac agtaaaggtg tcgttaaatt cgtgatcgaa gctgtagccg
    46741 accatcttct cattacgaga ataggtgttg ttcttcgccc cttcattaaa gtctgtcggc
    46801 agacgcttac cgttcggcag cggctcaacg gttccctctt tcggcaacca gccgtaataa
    46861 ccggtttccg gctcgttctg gaagtaagaa aggaaggtga aattggtttt atcatccgga
    46921 cgccaggtga acgccggtgc aatagcataa cgctgctctt ctgacccttt ctgctgggca
    46981 ttggcagaac gcgcaagacc ggtcaggcga taagagtaaa caccgtcatc atccaacgaa
    47041 tcgctaaagt caaaaccagt ctggaacagg ctgtcagtac cggctttaaa ctgaacttct
    47101 ttcagcggtt cggtggtcgg acgcttgctg accatattca acaggccgcc aggactgctt
    47161 ttaccgtaaa gcacggaaac cgggccacgc ataatttcag cgcgttccag catatacggg
    47221 tcaatgaccg catcgttata gaagttgccc tgcaacttca ggccattcag atagttattc
    47281 tggctttggc cttctgccgc aaagccgcga atgatcaggt ggtcataggt gttggatgcg
    47341 ccacgcgtac caacagagac acccggcgtg tagctaagcg cttcttttac cgacttcggc
    47401 tgatgcagcg ccatctcttc ggcggtcaca acagaaatag actgtggcac tttttgaatc
    47461 ggcgtatcgg ttttagtgcc ggtagcagac tgtcgcgccg caatagttgc agcaggcccc
    47521 catgcgcttt cttgcggcgc aggtgcagcg gtaacggtga tagtgtcttc tttcggttca
    47581 accgctgcct gtgcataaac agacatgccg cttaccgctg tggctactac aactgcgatt
    47641 ttacgcagtg agtgttttgg ctgagcagtt ttggaacgcg ccattggtat atctctgatg
    47701 taaagtgaat gataacgtaa acgagaatga ttattataaa gataagataa tattcgaaac
    47761 gctggcgggt tcgcaagcgg tacgcaatct gagcgttcct gaagggttaa taaacaacca
    47821 gatgaaaaga aagggttaat atcttagatg ggatgttatt ttaccggatg gcaactcgcc
    47881 atccggtatt tcacgcttag atgttaatta ctaccaaaca tatccttgat ccaaccggct
    47941 acaccgtcgc tgtctttctg ctcttgctga gcaggttgct gttgcggctg ttgctgcggc
    48001 tgagaagact gatcaaacgg attgcctgac ggctgctgct gcatctcgct ctgctggcac
    48061 agcgattgcg gatcgctggt ccagaccggc aagacacgca tgccaccgct gcaaacaaag
    48121 ttgccgtcgt agtccacgcc catatctgca atatcttctg gcggaacaag attcagcggc
    48181 gttggcgtct ggttagccag ataacgctga taaatcgaca ttgccccgct ggctccatac
    48241 agtttggtcg gctggttgtt atcacggcct acccaggtga tggtcaccgt gctgccgtca
    48301 atgcctgcaa accaggtatc tacgttattg ttggtagtcc ctgttttccc tgccagatgc
    48361 aggttcgggt atttcgcccc aagctgacga cccgtaccgc gttgtaccac ctgctgcatg
    48421 gtccatagtg tcagatacgc cgcctgcgcc ggaacagcgc gttccgcctg cgggaagctc
    48481 tgatacagca ccttgccatc ttccgcaatt accgaacgca gtgcagaaag cggtgcacgg
    48541 ttaccgccgc tggcgatggt ctggaacgcc tgcgccactt cgattggcgt taagttcaac
    48601 gcccccagca gcatcgccgg aaccggatgc aactgatctt tcggtacgcc cagtttgatc
    48661 caggtctccg taaccgcagg cagccccagc gccatcccca gatttaccgt cggcacgttc
    48721 atcgaacggg tcaacgcatc caccagcatc actctgccgc tttcgctata acgacggtca
    48781 tcattctgcg gtgaccagac ctggccattc ggctgacgca gcgcgattgg cgcatccgca
    48841 atccacgtat tcagacgata gattttcggc tggcttaagg cagtcagata agtcgctggt
    48901 tttgcaaggg aaccaatcga acgacgcgcc tgcatcgcac ggttgtagcc cgcaaactgc
    48961 ggctcagaac caccgaccat cgcacgaact tcaccactaa agcggtcgac gaccacaatc
    49021 gcagtttcaa gatcgctcaa cttacgctgt ttcttcagtg ccggaatgcc ttccacggcg
    49081 gctttttctg ccgcgtcctg ggccaccgag tcaaaggtag tgaagatctt cacgccggag
    49141 agatctttta ccttatcgcc taatttcgcc tgcagctcct gacgcaccag ttgcataaag
    49201 gctggctgtg gagagatcac cccaccgcgt ggctgaacac ccagcggacg tgcactcaac
    49261 atgtcataga gttcttgatc aataatctgt tgctgttgca gcagacgcag caccagatta
    49321 cgtcgctcca gcgccagttt tgggttacgc cacgggttgt agatggacgc ccctttcacc
    49381 ataccgacta acagcgcctg ctggtcgagg cttagctctt ctaccgggcg accaaagtaa
    49441 tacaagcttg ccagcgggaa gccgcggatt tcgttgtcgc cgctctgacc gagatacacc
    49501 tcgttcatat acagctcaag aatacggtct ttgctgtaac gcgcgtccat gatcagcgcc
    49561 atgtaagctt cgttcgcttt acgccagtaa gaacgctcgc tggagaggaa caggtttttc
    49621 accagctgtt gcgtcagcgt actcgcaccc tgtaccgtgc gtccggcggt caggtttgcc
    49681 agcaccgcac gtccgattga gtagagactg attccatcat gctcgtaaaa atgacggtct
    49741 tctgtcgcca gcaaagtatc caccagcaaa tccgggaaac cactgcgcgg cacaaacaga
    49801 cgctgctcac cgtttggcga agagatcatg gtgatcagac gcggatcaag acggaagaaa
    49861 ccgaactgac ggttgttctc catattgacg atcgtcgcca gatgatcgcc atcaaaggtc
    49921 agacgcgcgc gcacctgtcc ttctttactg tccgggaaat caaacggacg gcgaatcatc
    49981 tcaatgctgt tggcctgcac ggtaaattcg ccaggacggg tcattttcga cacctgacga
    50041 tactgggtcg cctccagcag cttcaccatc tcgttcttgc tgatggtcat gtctggctca
    50101 agattgacca ttcggccata aactgccgca ggcagttgcc agaccttgcc atcaatacgg
    50161 ctacgaattt tttgatcgag ataaacgccg taaatggcga tcagcacggc aaaaacgata
    50221 gccagtttta gcagtagcca tagccagccg cgtttgccac gaggcttacg ccctttgcct
    50281 ttgcccttac ctttgcgcgg catcggttct tcatcctcat agtcatcata atcgtcgtaa
    50341 tcatcgtcat cttcgtaacg acgacggctt accttttgtt tgaccggacg cgtcggtttc
    50401 cctttgcgtc caattggctc gcggtcattc ccggccatgc tttttctccg caatattcag
    50461 gcgcaaaagc ccgattttct gttcttctgt tacaagacag aagaagatat ctctcaaaat
    50521 ttgtgctcga tcggtcccct ctcccttgag ggagagggtt agggtgaggg tgaacgtgcg
    50581 cgctgatgcc ctcaccccgg ccctctccca cagggagagg gagaaaacca accttacgaa
    50641 tactttttcg tccgtcgcgt cggtgcagta tttgccgggt cgtccggcca gacatgtttg
    50701 ggataacgcc ctttcatctc tttttgcacc tcacggtacg ctcctttcca gaaggcgctc
    50761 aaatctcgtg tgatttgtaa tggcctttgg gcaggtgaaa gcaactccag caccagcggc
    50821 acgcgcccct gggcgatcgt cggattggtg gcctcgccaa acatctcttg cattctcacc
    50881 gccagcgcgg gcgggttatc ttcatgataa cgaatggcga tccggcttcc cgtcggcaca
    50941 gtgtaatgcg caggcaattc actatccaga cgttgctgca ttccccaatc aagtaatccg
    51001 cgtagtgcct gataaatgtc gagtgatttc aggccgcgta gtgaatgtac gccagtcata
    51061 tgtggcagca gccacgtttc cagcgtcgcc aataaacttt catcatcaac cgctggccag
    51121 tcatattccg gcaaccactt tgcggcgcat aacaaacgca agcgtagctg ttccgcttcc
    51181 gccgtccagt tgagcacgct taaacctttt tcacgaatgc cgttaagcat cgcctgatgc
    51241 aactcgtctt ctgacggttt cgccagtggc tgcactttca ccgtcaactg accgatttgc
    51301 agccgacgcc aggctttcag cgtaccttgc gcgtcatccc attccacggt gtcagattgc
    51361 tgcaccagct gcggacagcg ttgtactaat tcatcaatat cgaccggtaa cgccagtaaa
    51421 atccgcgcat ccggcgaggc gctgccctgc aataataacg gtgcgatcaa ccattcgtgg
    51481 cggcttagcg cgtcgttggc atcgagcatc gctcccatgc cgtttgccag ttgatagcgt
    51541 ccatcttgcc cacggcgacg agcaatgcga tcggcaaacg ccccggcaag tagcggcgcg
    51601 ataagcgaac tgtctgcctc accgccacgt acgtttaagc gttttaacag ttgctgacta
    51661 cgttgctgcc aggctggttg attgcgcgaa aacgccacgc ccaggtcact attgcccatc
    51721 cgtggcggct cttcgagaat ggcggcaatt tttgccgcgg tagcagcttc gtcgtcgttc
    51781 ttcgcgctaa ccagcattgc cgctaaacgc ggatcgttac ccagcgctgc cattttttgc
    51841 ccctgcgcac taagccgttc accctccagc gcccccagca tttgtaacag gcgtttcgcg
    51901 gccagtagat tcaccgttgg cggttgatcc agccagctca tctgcgccgg atcgctgcat
    51961 ccccattgca gtaattccat cagaaaaccg gaaagatcgc tttgtaagat ctccggttca
    52021 ctttgcgccg cggcgcgttc tgcttgttct ttggcgatta aatgcaggct gatacccggc
    52081 tccagacgcc cggcgcgccc ggcacgctgc gtcatggatg cctggctaac gcgttgagta
    52141 atcagtcgcg taagccccgt gcgcggatca aaacgcgcca cacgctcctg ggcacaatcc
    52201 accaccagac gaataccttc aatggttaaa ctggtttcag caatattggt cgccagcacc
    52261 actttgcgca tcccttgcgg tgccgggagg atcgcttttc gctgatcgtt cagcgacaac
    52321 gcgccataca gcgggcagag caacacatca ctgccgatgc gcgaagccag ttgctcctgc
    52381 acacgctgaa tttctccgac gccaggtaaa aataacagta atgatccgct ttcctgacgc
    52441 agcatttcgg cggtggctac cgcaacggct tcgtcaaaac gctgatgcgc gggcagcggt
    52501 aaataatggc gttcaaccgg aaacgagcgc ccttctgaga tgacgacggg cgcttctggc
    52561 agcatttgct gcaagcggtc gttatccagc gtagccgaca taatcagcag tttaaggtca
    52621 tcacgcagac cttgttgcac atcgagtaac agcgccaacg ccaaatccgc ctgcaagctg
    52681 cgctcatgaa attcatcgag gatcaccaat ccaacaccgc tcagttccgg gtcacgctgg
    52741 atcatgcgcg tcagcacgcc ttcggtaacc acttccaggc gggtattcgg cccgacgcag
    52801 ttttgcgcac gcatccggta gccaacggta tcgcctggct tttcgttaag cagctccgcc
    52861 agtcgttgcg cgacgttacg cgccgccaga cgacgcggct ccagcaggat aattttcccg
    52921 ttaatgccgg gatgcgccag cagttgcagc ggcagccagg ttgatttccc ggccccggtc
    52981 ggcgcactta ataatacctg cggcgcacaa tcgagagcgg taagtaattc agataagacg
    53041 gcagcaacgg gcaacgacga cacaaaacgc tccagagggt taacattctt cgcgccacat
    53101 tgtagcatcg cggtaattca taaccgagtg cctcacatgt ctgaaccgca acgtctgttc
    53161 tttgctatcg acttacctgc agaaatccgc gaacagatta tccattggcg cgccacacac
    53221 ttcccacctg aggcgggacg tccggtcgcc gccgataatt tgcatctgac tctggcattt
    53281 ttaggcgaag tgagcgccga gaaagagaag gcgctttctc ttttagccgg acggattcgt
    53341 caacctggtt tcacactcac gcttgatgac gccggacaat ggctgcgttc gcgtgtggtg
    53401 tggttaggga tgcgtcagcc tccacgcggc ttaatccagc tggcgaatat gctccgttca
    53461 caggctgccc gcagcggttg ttttcaaagc aatcgtccgt ttcatccaca tattacctta
    53521 ttgcgcgacg ccagcgaggc ggtgacaatc ccgccgccag gttttaactg gtcttatgcg
    53581 gtgacggagt tcacccttta cgcctcctcg tttgcccgtg gacgcacacg ctacacgccg
    53641 ctaaaacgct gggcgctaac gcaataacaa ggattgtcgc aatggaattt tctccccctc
    53701 tacagcgcgc gacgctaatt cagcgttaca aacgtttttt agccgatgtg atcacacccg
    53761 atggtcgcga attaacgcta cactgcccga atacgggtgc gatgaccggt tgtgcaacgc
    53821 ctggcgatac cgtctggtat tcgacttcag acaacaccaa acggaaatac ccacacacct
    53881 gggaactaac tcaaagccag agcggcgcat ttatttgcgt caatacgctt tgggctaaca
    53941 ggttgacgaa agaggctatc cttaatgaat caatttcaga actgtcaggc tatagctcgc
    54001 tgaaaagcga agtaaaatac ggcgcagaac gcagccgtat tgactttatg ttgcaggcgg
    54061 attcgcgtcc agactgctat attgaagtga aatcggttac gttagcggag aacgaacagg
    54121 gatattttcc cgatgcggtc actgaacgag gtcagaaaca ccttcgggag ttgatgagcg
    54181 tagcggctga aggccagcgt gcggttatct ttttcgccgt gctgcattca gccattacac
    54241 ggttttcacc cgcgcgccac atcgatgaga aatacgcgca actattgtca gaagctcaac
    54301 agaggggggt agaaattctg gcttacaaag cggaaatttc tgctgaaggc atggctctta
    54361 aaaaatcact gccggttaca ttgtagtaaa gtaagtaact ggttaattta cattctggtc
    54421 gcgtgcgcaa atacgctttt cctcacacag ttgtcaagtg ttacgtttag ataattgcta
    54481 tccggaaaag catctgctat ttatagcggc ctcatttttc ccccgaacat ggggatcgat
    54541 agtgcgtgtt aaggagaagc aacatgcaag aagggcaaaa ccgtaaaaca tcgtccctga
    54601 gtattctcgc catcgctggg gtggaaccat atcaggagaa gccgggcgaa gagtatatga
    54661 atgaagccca gctggcgcac ttccgtcgta ttctggaagc atggcgtaat caactcaggg
    54721 atgaagtcga tcgcaccgtt acacatatgc aggatgaagc agccaacttc ccggacccgg
    54781 tagaccgtgc agcccaggaa gaagagttca gcctcgaact gcgtaaccgc gatcgcgagc
    54841 gtaagctgat caaaaagatc gagaagacgc tgaaaaaagt ggaagacgaa gatttcggct
    54901 actgcgaatc ctgcggtgtt gaaattggta ttcgccgtct ggaagcgcgc ccgacagccg
    54961 atctgtgcat cgactgcaaa acgctggctg aaattcgcga aaaacagatg gctggctaat
    55021 tacagccgtt ccatcacgtt taccacaggc gggaaatgct cccgccttat tttttgttca
    55081 aagagatgac agacacacag tatattggcc gcttcgcccc ctctccttcc ggcgagcttc
    55141 attttggctc tctgatcgcc gcgctcggca gctatttgca ggctcgcgcc cggcaaggtc
    55201 gctggctggt acgcatagaa gatatcgacc cgcctcgtga agttcccggt gccgcagaaa
    55261 ctatcctgcg ccagctggaa cattacggtc tgcactggga cggcgatgtt ctctggcaat
    55321 cgcaacgtca cgacgcctat cgtgaagcac tcgcctggtt acatgaacaa ggactaagtt
    55381 attactgcac ctgtacgcgt gcgcgtattc aaagcattgg cggtatttac gacggtcatt
    55441 gccgggtgtt gcatcatgga ccagacaacg ccgcagtgcg tatccgccag cagcatccgg
    55501 tcacgcaatt tactgaccag ctgcgcggca ttattcacgc cgacgaaaaa ctggcacggg
    55561 aagattttat cattcatcgc cgtgatgggt tgttcgccta caacctggct gttgtggttg
    55621 atgatcattt ccagggcgtt acagaaatag tgcgtggggc tgatctgatt gaaccaacag
    55681 taaggcaaat ctcgctgtac cagctttttg gctggaaagt gccagattac attcatctgc
    55741 cgctggcgct taatccacaa ggcgctaaac tttccaagca gaatcatgcg cctgcgttgc
    55801 cgaaaggcga tccacgcccg gtactaatcg cggcacttca atttctgggg cagcaggcag
    55861 aagcacactg gcaggatttc agcgtcgagc aaatccttca gtcagccgtc aaaaactggc
    55921 ggcttaccgc cgtgcccgag tcggcaattg taaattcaac attctcaaat gcgtcatgct
    55981 gagctatgat tagccgctat ttttttgtcc tgaatgatgt ttgacactac cgaggtgtac
    56041 tatttttacc cgagtcgcta atttttgccg caaggtgcta agccgcgagg aaagcgaggc
    56101 tgaacaggca gtcgcccgtc cacaggtgac ggtgatcccg cgtgagcagc atgctatttc
    56161 ccgcaaagat atcagtgaaa atgccctgaa ggtaatgtac aggctcaaca aagcgggata
    56221 cgaagcctgg ctggttggcg gcggcgtgcg cgacctgtta cttggcaaaa agccgaaaga
    56281 ctttgacgta accactaacg ccacgcctga gcaggtgcgc aaactgttcc gtaactgccg
    56341 cctggtgggt cgccgtttcc gtctggctca tgtgatgttt ggcccggaga ttatcgaagt
    56401 tgcgaccttc cgtggacacc acgaaggtaa cgtcagcgac cgcacgacct cccaacgcgg
    56461 gcaaaacggc atgttgctgc gcgacaacat tttcggctcc atcgaagaag acgcccagcg
    56521 tcgcgatttc actatcaaca gcctgtatta cagcgtagcg gattttaccg tccgtgatta
    56581 cgttggcggt atgaaggatc tgaaggacgg cgttatccgt ctgattggta acccggaaac
    56641 gcgctaccgt gaagatccgg tacgtatgct gcgcgcggta cgttttgccg ccaaattggg
    56701 tatgcgcatc agcccggaaa ccgcagaacc gatccctcgc ctcgctaccc tgctgaacga
    56761 tatcccaccg gcacgcctgt ttgaagaatc gcttaaactg ctacaagcgg gctacggtta
    56821 cgaaacctat aagctgctgt gtgaatatca tctgttccag ccgctgttcc cgaccattac
    56881 ccgctacttc acggaaaatg gcgacagccc gatggagcgg atcattgaac aggtgctgaa
    56941 gaataccgat acgcgtatcc ataacgatat gcgcgtgaac ccggcgttcc tgtttgccgc
    57001 catgttctgg tacccactgc tggagacggc acagaagatc gcccaggaaa gcggcctgac
    57061 ctatcacgac gctttcgcgc tggcgatgaa cgacgtgctg gacgaagcct gccgttcact
    57121 ggcaatcccg aaacgtctga cgacgttaac ccgcgatatc tggcagttgc agttgcgtat
    57181 gtcccgacgt cagggtaaac gtgcatggaa actgctggag catcctaagt tccgtgcggc
    57241 ttatgacctg ttggccttgc gagctgaagt tgaacgtaac gctgaactgc agcgtctggt
    57301 gaaatggtgg ggtgagttcc aggtttccgc gccaccagat caaaaaggga tgcttaacga
    57361 gttggatgaa gaaccgtcac cgcgtcgtcg tactcgtcgt ccacgcaaac gcgcaccgcg
    57421 tcgtgagggt accgcatgac agtggcgtat attgccatag gcagcaatct ggcctctccg
    57481 ctggagcagg tcaatgctgc cctgaaagca ttaggcgata tccctgaaag ccacattctt
    57541 gccgtttctt cgttttaccg caccccaccg ctggggccgc aagatcaacc cgattacctc
    57601 aacgccgccg tggcgcttga aacttcgctc gccccggaag agttactcaa ccatacacag
    57661 cgcatagaac tgcaacaggg tcgtgttcgt aaagctgaac gctggggacc acgcacgctg
    57721 gatctcgata tcatgctgtt tggtaatgaa gtgataaata ccgaacgcct gaccgttccg
    57781 cactacgata tgaagaatcg tggatttatg ctgtggccgc tgtttgagat tgcaccggag
    57841 ctggcgtttc ctgatgggga gacgttgcgt gaagtcttac atacaagagc atttgacaaa
    57901 ttaagcaaat ggtaatttat ttatattacg aatataaata ttttctgaaa atcatacatc
    57961 ctctctttcc ttaataaaaa ttttagttta aacatttttg cagaaacata atataaattc
    58021 ccgcagataa atatcaatcc catcgccata ccctaaccaa ttgcacttgt gaatttattt
    58081 ttgcttaatt ttgaattaag aaaatttaat ttgttcaaaa gcccttaaag tgcacaatag
    58141 gcgtcctaat gaacaatggt tgtaaatttt ggtaacaaat atcattgctc attaatatct
    58201 agcatctgct tataacattt gtgtcatgaa tagtcattct tcaaaccagt agtctgacta
    58261 atggaatttt attcaaggat ttttatgtct aaaaaattag gttttgccct gtctggtctt
    58321 atgctggcaa tggttgcagg tactgcttct gctgatatgg atggtggtca gttaaatatc
    58381 agtggtctgg ttgttgataa cacctgtgaa acccgcgttg acggcggtaa taaagatggt
    58441 ctgatcctgc tgcaaactgc aactgttggt gaaatcgatg ctggcgtgct gaatgacacc
    58501 gttggcgcta aagccaaacc tttcagcatc accgttgact gcagcaaagc aaatccgaat
    58561 ccaggtagta cagctaaaat gaccttcggt tctgttttct ttggtaatag caaaggaacg
    58621 ctgaacaacg acatgtctat taacaacccg tctgacggcg tgaatatcgc tctgcacaat
    58681 attgatggtt ccactatcaa acaggttcaa attaacaacc ctggcgatgt gtatactaaa
    58741 gccctggatg caacgacaaa atctgctgtt tatgatttta aagcgtctta cgttcgtgcc
    58801 gtcgcagacc aaacagcaac tgctggttat gtaaaaacta acactgcata caccattact
    58861 tatcagtaag tattcaccaa ttaaattgat tgaatgaata tacagggaat agtgttaata
    58921 atttctattt ttatattatt ccctgtttta attaactctg tcagggatgg tttatgtttt
    58981 ttaacaccaa acatacaaca gctttatgct tcgtaacctg tatggctttt agttcatcgt
    59041 ctattgcgga cattgtcatt tcgggtactc gcgtaatata taaaagcgat caaaaaagtg
    59101 tcaacgtacg tctggaaaat aaagggaata acccgttgct tgtccagagt tggttagata
    59161 ctggcgatga caacgctgag cctggcagta ttacagtccc ttttactgcc acgccgccag
    59221 tatcgcgtat tgatgccaaa cgtgggcaaa caatcaaatt aatgtacaca gccagcacct
    59281 cactgcctaa agacagagag agcgtgttct ggtttaacgt actggaagtt ccaccaaaac
    59341 cagatgcaga aaaggtcgcg aatcaaagtc tgctgcaact ggcatttcgc acacgtataa
    59401 aacttttcta tcgcccggat ggattgaagg gaaatccctc tgaagccccg ttagccctga
    59461 agtggttctg gtcaggttca gaaggtaagg cgtcattgcg agtgaccaat ccaacccctt
    59521 actacgtctc ttttagcagt ggtgatttag aagctagcgg taaacgctat ccgattgatg
    59581 tgaaaatgat tgcaccattt agtgatgagg tcatgaaagt cactggcctt aatggcaaag
    59641 caagttctgc aaaagtacat ttttacgcca ttaatgattt tggtggcgcc attgaaggta
    59701 atgccagtct gtaatcaggc aaggatataa ttccgcagga agcataacgt gactataaaa
    59761 ccaactaaaa attatcataa tcatctgacc cgtatcgcta cgttttgcgc gctgctgtat
    59821 tgcaatagtg ctttctgtgc tgaacctgtt gaatatgacc ataccttcct gatggggcag
    59881 aatgcctcaa atattgatct cagccggtat agtgaaggta accctgctat accgggtatg
    59941 tacgacgtca gtgtttatgt caacgatcaa cctattatta accaaagcat tacatttatt
    60001 gaaattgaag gaaaaaaaaa cgcacaagcc tgtatcacac ttaagaattt attgcagttt
    60061 catataaatt ctcccgatat aaataacgaa aaagccgttc tgcttgccag ggatgaaaca
    60121 ctcggcaatt gccttaattt gacggaaatt atccctcagg cttctgttcg ttatgacgtt
    60181 aacgagcaac gtctggatat agacgttcct caggcatggg taatgaaaaa ttaccaaaac
    60241 tatgttgatc catcgttatg ggaaaatggc attaatgcgg ccatgttgtc atacaacctc
    60301 aacggatatc atagtgaaac tcctggtcga agaaatgaca gcatttatgc tgcttttaac
    60361 ggtgggatga atttaggtgc atggcgactg cgtgcctcag gcaactacaa ctggatgacc
    60421 gattctggca gtaattatga ttttaagaat cggtatatac agcgtgatat cgcctcgctg
    60481 cgttctcaac tcattcttgg tgagtcttat acaacgggcg aaacctttga ttctgtcagt
    60541 atccgcggca ttcgtttata cagcgacagc cgcatgttgc ctccgacatt agcgagtttt
    60601 gcgcctatca ttcatggcgt tgctaatacc aacgccaaag tcactattac gcaaggtggc
    60661 tataagattt atgaaacgac tgtgccgcca ggcgctttcg tcattgatga tctgagtccg
    60721 tcaggttacg gcagcgatct tattgttact gtcgaagaat ccgatggctc aaagcggaca
    60781 ttctcgcaac ctttttcatc ggtcgttcaa atgttacgcc ctggcgttgg acgttgggat
    60841 attagcggcg gccaggtctt aaaagatgat attcaggatg agcctaattt atttcaggcc
    60901 agctactact acggtctgaa taactatcta acgggttata ctggtattca gattaccgat
    60961 aataactata ccgctggttt gttaggtctt ggtctgaata cttcagtcgg tgcattttct
    61021 ttcgatgtga ctcactccaa tgttcgtata ccggatgata aaacatatca gggacaaagt
    61081 tatcgtgttt cctggaacaa gttattcgaa gaaacaagta cttcactgaa tatcgcggcc
    61141 tatcgctatt cgacacagaa ttaccttggt cttaatgatg cactaactct aattgatgaa
    61201 gtgaaacatc ccgaacaaga tcttgaaccg aaatccatgc gtaattactc gcgcatgaaa
    61261 aatcaggtta cggtcagtat taaccaaccg ctaaaatttg agaaaaaaga ttacggttca
    61321 ttttatcttt ccggaagttg gtccgattac tgggcttccg gacaaaatcg tagcaattac
    61381 tctattggct acagtaacag tgcatcctgg ggcagctaca gtgtcagtgc ccagcgttca
    61441 tggaatgaag acggcgacac tgacgatagc gtttatctca gtttcaccat tcctattgaa
    61501 aaattacttg gcactgaaca acggacttca ggtttccaga gtattgatac tcaaatgagc
    61561 agtgacttta agggtaataa ccaactcaac gtcagtagca gtggctatag tgataacgct
    61621 cgcgtcagtt atagcgtaaa tactggctat acgatgaata aagccagcaa agatttgagt
    61681 tatgttgggg gttatgccag ctatgaatca ccgtggggaa gcctggcagg ttcagtttct
    61741 gcaaatagcg ataacagtcg tcaagtgtct ctcagcaccg acggtggttt tgtattgcat
    61801 agcggcggcc tgaccttcag taatgacagt tttagcgact ccgatacact ggcggtagtt
    61861 caggctccag gtgctcaagg agcgcgaata aattatggca acagtactat cgatcgatgg
    61921 ggttatggtg tcaccagcgc tctttctcct tatcatgaaa accgtatcgc gctggatatc
    61981 aacgatcttg agaacgatgt tgaattaaaa agtaccagtg cagtagctgt accgcgtcag
    62041 ggttcagtcg tctttgctga ttttgaaacc gtgcaagggc aatcagccat tatgaacatc
    62101 acacgaagtg atggtaaaaa tattccattt gctgcagata tttatgatga gcaaggcaat
    62161 gtcattggta atgttggaca gggtggacaa gcatttgttc gtggtattga gcagcaggga
    62221 aatatcagca ttaaatggct cgaagaaagt aaacccgtaa gttgtcttgc gcattatcaa
    62281 caaagttcag aagcagaaaa aatagcgcaa tctattattc tgaatggaat tcggtgtcag
    62341 attcagtaac tacaagggac gtcaaatgat aaaaataacg ccacataaaa tagcgatact
    62401 gatgggaata ttattatcac catcagtatt tgcaacggat attaatgtag agtttacagc
    62461 cactgtcaaa gcgacaacct gtaacatcac acttactggt aataacgtca cgaatgatgg
    62521 caataataac tacacattga gaatccctaa gatgggtctg gataagatcg cgaataaaac
    62581 gacagaatct caggctgatt ttaaactggt tgctagtggg tgcagcagtg gcatcagttg
    62641 gattgatacc actctgaccg gaaatgcatc atcaagctca cctaagctta ttataccgca
    62701 gtctggtgat tcatcttcga cgacaagtaa tatcggtatg ggtttcaaaa aacggactac
    62761 tgatgatgcc actttcctta aacctaacag tgcggaaaag atacgctgga gcacagacga
    62821 gatgcagccc gataagggtc ttgaaatgac cgttgcgcta cgtgaaacag atgcagggca
    62881 aggcgtaccg gggaattttc gtgcactggc aacgtttaat ttcatctatc aataagaagg
    62941 ataattaaga tgacatttaa aaatttacgt tatggattat ccagcagtgt cgttttggct
    63001 gcctcattgt tcagcgtacc ctcttatgcg gcaacagaca gcattgggct gaccgtgatt
    63061 actaccgtag aaataggtac ttgtactgct acattagtaa atgactctga tcaggacatt
    63121 tctgttgttg actttggcga tgtatatatt tctgaaatca atgccaagac caaagttaaa
    63181 acattcaaac tcaaattcaa agactgtgcg ggtatcccca ataaaaaagc acaaataaaa
    63241 ttaaccaagc gagccacatg cgaaggtact gctaatgacg gtgcggggtt cgcaaatgga
    63301 tccacagccg cagataaagc aagtgccgtc gccgttgaag tctggagcac cgaaactccg
    63361 gcaacaggga gcgcaacaca atttagttgt gtgacaccag catctcaaga ggtcactatc
    63421 tccaatgcag ccaacgcggt tgtttattat ccgatgagtg ctcgactggt cgtcgaaaaa
    63481 aataaaaccg taagcaatgt cactgcgggt aaattttctg cacctgccac atttacagta
    63541 acctataact aacagactga cagatccagg aactatatat gcatcccact caacgtaagc
    63601 tgatgaagag aataattctg tttctgtcac tacagtttcc cattacctat ccagccatcg
    63661 ctgggcagga tattgacctt gttgccaatg taaaaaacag cacttgcaaa agcggaatca
    63721 gtaaccaggg taatattgat cttggcgtcg ttggggtggg atatttttca gataatgtta
    63781 ctcctgaaag ctatcaacca ggtggaaaag agttcactgt cacagtatca gactgtgcat
    63841 tacagggaac tggcgatgtg cttaatcagt tacatattga ttttagagcc cttagcggtg
    63901 tcatggctgc aggttcaagg caaatatttg ccaatgaagt cgcaaccggg gctaaaaatg
    63961 tcggtgtcgt tctcttttcc attcaggacc cgaccaatat attcaatgtt attagttcag
    64021 caggaaattc tcgttccgtg tatccagtaa tgacttctgc cctgcataat tcttcatgga
    64081 aattttatgc cagaatgcaa aaaatcgatc ccgcgctgga tgtcatatct ggccaggtaa
    64141 tgagtcatat attagttgat gtgtactacg aataatagat caaaacaaat aactgcgact
    64201 gttacagcag tagatggtgg agtgataatg aagaaattct tcagacattt tcttttttta
    64261 attctgtgct tgagttgtta taccgcgagt gctggcactg atgataacgt aggatatatt
    64321 gttgggaata gttacggcgt tggtccgtca gatcaaaaat ggagagaaac ggggccgaat
    64381 ggcgatgcta ctgtcatatt cagatatgca acaagtacaa ataatttagt tttctacaaa
    64441 ccgacgcagc ttggacctac aggtgtaaaa ttacagtgga gtcagttaga taccgcttct
    64501 ggtggtggtt ttctttattg caacagaagt gatagcacaa gtggtagcgc aatgcgtatt
    64561 gaaaatgcaa tggttgactc aggtaaaatg tatggctccc ataaattatt taatacatca
    64621 gttcctggtt tgtattacac attattaatt tcaaacatgt ggtcagctta cggtaccgta
    64681 actaacgtta gttcacctgg gatatacatt ggtgactctg cagaacaata tttttcgtgg
    64741 tataatccaa gcgaagacgt gttatattgg agttgcaata atgcgaatag cacccgtaaa
    64801 tactgggctg taggtggtat ttatcagacc cttacaattg aattctatac agatacaaac
    64861 tttgatccaa cagtaactca acagatcaaa ttatccagct catcaaatta tctgtattca
    64921 tttaaagcct atggcgcagg ccaaggtata aatgagcata gttattttat caaaatcgat
    64981 ttcgatctgc tcaatgtcaa gttgactaat cccacttgtt ttaccgctat gcttagtgga
    65041 acttctgtga ctggttctac ggtaaaaatg ggtgaatata gtgcagaaca aatcagaaac
    65101 ggtgccacac cggttccttt tgatatttca cttcaaaact gcgttcgtgt gactaatatt
    65161 gagacaaaat tagtttcaac aaaggttggt actgaaaacg ggcaactcct tggtaatact
    65221 ctcacaggta atgacgcagc aaaaggagtc ggtgtactca tagaaggttt agcaactagt
    65281 aaaaatcctc taatgacatt gaaacctaat gattcaaatt ctgtttataa agattacgac
    65341 ccaagaggca aagacgatac aacaggagga gtttacccgg atcaagatac aggtataaca
    65401 taccctctcc atttccaggc cacgctacaa caggatggaa ctataccaat agaagctggt
    65461 gagtttaaag ccaccagtac tttccaggta acctaccctt aataagtcca ccgcaccgcc
    65521 atcatctggc ggtgcggtaa ttgataaatc attgccccca ccaatgtgac tgataaaatg
    65581 ccaggcaaca cgacatcatt tatcaggaca cgttatgaaa ccgaccacca ttgcttcact
    65641 tcagaaatgt aagcaggata aaaagcgttt cgcgaccatc accgcttacg actacagctt
    65701 cgcgaaacta tttgctgatg aaggacttaa cgtcatgctg gtaggcgatt cgctgggcat
    65761 gacggttcag ggccacgact ccacccttcc cgttaccgtc gaggatatcg cctatcatac
    65821 cgccgccgta cgtcgcggcg cgccaaactg cctgctgttg gctgacctgc cgtttatggc
    65881 gtatgccacg ccggaacaag cctttgaaaa cgccgcaacg gttatgcgtg ccggtgccaa
    65941 tatggtcaaa attgagggcg gtgagtggct ggtcgaaacc gtaaaaatgc tgaccgaacg
    66001 tgccgttcct gtatgtggtc acttaggttt aaccccacag tcagtgaata ttttcggtgg
    66061 ctacaaagtt caggggcgcg gcgatgaagc gggcgatcaa ctgctcagcg atgcattagc
    66121 cttagaagcc gctggggcac agctgctggt gctggaatgc gtgccggttg aactggcaaa
    66181 acgtattacc gaagcactgg cgatcccggt tattggcatt ggcgcaggca acgtcactga
    66241 cgggcagatc ctcgtgatgc acgacgcctt cggcattacc ggcggtcaca ttcctaaatt
    66301 cgctaaaaat ttcctcgccg aaacgggcga catccgcgcg gctgtgcggc agtatatggc
    66361 tgaagtggag tccggcgttt atccgggcga agaacacagt ttccattaag gagtcacgtt
    66421 gtgttaatta tcgaaaccct gccgctgctg cgtcagcaaa ttcgccgcct gcgtatggaa
    66481 ggcaagcgcg tggcgctggt gcctactatg ggtaatctgc acgatggcca tatgaagctg
    66541 gtcgacgaag ccaaagcccg cgccgatgtg gtcgtcgtca gtattttcgt taacccgatg
    66601 cagttcgacc gcccggaaga tctggcacgt tatccacgga ccttgcagga ggactgcgag
    66661 aagctaaaca aacgtaaagt ggatttagtt ttcgcccctt cggtaaaaga gatctacccg
    66721 aacggtactg aaacccatac ttacgttgac gttcccgggc tttcgaccat gctggaaggc
    66781 gcgagccgtc cggggcattt tcgcggcgtt tcgactatcg tcagcaagct gtttaacctg
    66841 gtccagccgg acatcgcctg cttcggtgaa aaggactttc agcaactggc gctgatccgc
    66901 aaaatggttg ccgatatggg cttcgatatt gagattgtcg gtgtgccaat tatgcgcgcc
    66961 aaagacggtc tggcgctaag ttcccgtaac ggttatctga cggcggaaca acgcaaaatt
    67021 gcgcctggtc tgtacaaagt tttaagttcg attgctgaca aattgcaggc tggggaacgg
    67081 gatctcgatg aaattattac cattgcgggg caagaactga atgaaaaagg cttccgcgcc
    67141 gatgatattc agattcgcga tgccgacaca ttgctggaag tttctgaaac cagcaaacgg
    67201 gcagtaattc tggtagccgc ctggcttggc gatgctcgcc tgatcgacaa caaaatggtc
    67261 gagctggcgt aatacttaac tggcgctacg gctgatggcg ccagttatta atttacccca
    67321 cgtcatctgt cataacacag gtaacttaaa taaggttaat taccttatca atctcagcaa
    67381 gagataaatt tgtcatctct gcaacgtctt cccgagacat tcctttactt agaagacgca
    67441 gggcgaattc ttgcctttcc tcctgtcttc cctgctgaat ccccttctca atccctttct
    67501 cttcaaacca ctgcgccagc gtcatcatag actcccctcc cgtttccctg tctctcagca
    67561 caccataaaa caaatccgct tgttcagtat gaccgcgttg cagcatatag ttttgcatgg
    67621 caactaactg acttccgcta gtgtaccctt cgtcaatcag cgtgaccagt tgctccagca
    67681 ataacattaa gtcgcgctgg cgaatatgtt tttgcagtag ttcgagaatc gcaatccgcc
    67741 gatgttgcat gatttcgtca tccggtgtga tggtgatatc caccagcggg aaaggactgt
    67801 tatagacgcg tcgtgccagc tccggcgagt aaaatatatc aaaccagcac attgagagcg
    67861 gataaggtgt ggcctcgccc tgataaaaca gtatcggcac caccagcggc agcttatcgt
    67921 gatccgcctc cagatgccgg tgcatggcag caatagaata acgcatcatg cgaaaggcca
    67981 ttttcttatc cggcttgctt tggtgttcaa tcacaacatg cagataaccg ggattgccct
    68041 gcatttgcac ggaatagagc acgtccgtgc tgtgtccttt caggctctct tcaatgaaac
    68101 tccccgactc taaatgaagc gtgttgaggt cacaaagttc tcgtaattcc actggcaaat
    68161 gtatctccag aaagtcgcga gccgtctccg catgcattaa aaattgttta aataccgcgt
    68221 catgcggtgt ggtactcggt gcatccatct tccctgtctt ccgtgttgtc ttgcgtgaag
    68281 gcagtatcca gtcaaggcgc gccgtcgtca gccgcctctt tagtgtttac cgagcagcgt
    68341 tcagagaaat ttcaattcgt tacaggcgat acatggcacg cttcggcgcg gtacgcaaac
    68401 tgctgacgca aatgccatca gatgagtaga cactcatcaa aaatcgggca atactgcgtg
    68461 agaatttcct caaagcaggc accgcctgct tcgttaacga cagggtagaa aggtagaagt
    68521 tatgattcgc acgatgctgc agggcaaact ccaccgcgtg aaagtgactc atgcggacct
    68581 gcactatgaa ggttcttgcg ccattgacca ggattttctt gacgcagccg gtattctcga
    68641 aaacgaagcc atcgatatct ggaatgtcac caacggcaag cgtttctcca cttatgccat
    68701 cgcggcagaa cgcggttcga gaattatttc tgttaacggt gcggcggccc actgcgccag
    68761 cgtcggcgat attgtcatca tcgccagctt cgttaccatg ccagatgaag aagctcgcac
    68821 ctggcgaccc aatgtcgcct attttgaagg cgacaatgaa atgaaacgta ccgcgaaagc
    68881 gattccggta caggttgctt gattgttatc cctgcggctg gttactcacc agccgcgaca
    68941 tcgtctccag cgaatccgtt cttaagatat aaagtcgttt tagtaacaac ggattatccc
    69001 ccggttttac tttgcctttc atggttgtca ccgccaggtg aaatccggca tcgtttgctg
    69061 ccttcacggc tttgtcatta aatccgccaa acggatacga aagataccag acatgcggat
    69121 taaattgcgc cagagcgcgg cgtgaacgtg caaaatcaaa cagaatattg tgctcactac
    69181 ggctcagtaa tatgggtcgg cgatagccat ccacccgatg caaaaaatgg gtatgtgact
    69241 gaaaatcaaa aacatcgcga atttcgttaa gctcagaaac gctcataaat tgcagcgatt
    69301 ttgggttcca cttctgcggg tgacgtttga tgcgcgaggt aacaacaaac gccgtcgcct
    69361 tcatgccata ttgtttcaat acaggatacg catagcggct caccgacttg aggccatcat
    69421 caaaggtaat caccaccgct cgcgcaggga gattgatctt attcttcacg taaccttcca
    69481 gctgcgccat gctcagtgtc gcgtatcccc tgtcgcgcag ccaggccatc tggttattga
    69541 aagcgcgtac cgaggtggtc gtcgaagtat ggcgaaaacg ggtgttttct tcatcgcgca
    69601 gaatatggtg ataggttagc accggcaggc cattatcggg ttgggcatcc agcgcgctga
    69661 tataggcgag tcgatcgcca atacggatct gataccaggt ttgatttaac ctgtctttca
    69721 gtttatgcaa aatcgggtag cgcaaattgt ccgccagtac cccaaatggc gcactgcccg
    69781 cactcggcgc gttatagacc ggcgtatctt tccaggtaat taagttctga ttactcagcg
    69841 gcttgttgag gtcacccaaa ccgtcttcaa ctttttgtcg cccctgaact ggctcgagat
    69901 gccctttatc gataaaccct ttaccaaagc caaaattaaa tgcgtaataa cttgcggcag
    69961 tgggctccac ggcaatgatt tgcccggccc gaatattccc cacggtcacc atcttgtcgc
    70021 caatttgcgc ccagatcgca gcattttcga tggtttgcat ataacgggca ggtaacgcgg
    70081 cactgacact tgcggtaaac agcatcagca ggagaataac agcttgtttg tacatgaaaa
    70141 aataaccgag ggtgaaacaa cgcttttatt gtagcaaaag cgctataaga atcgtgggtt
    70201 aatactcata caaattatgt ttgaggacga aaggcggatt tttttgttgt tggtgccaaa
    70261 gactactcac ctccggccca cccagttcga caatacgctc gcgaaactct gaactggtca
    70321 tggtttcacg gcaagccatc atctgttcaa ttaacggtaa cgtgacacca gaaatcactt
    70381 cgcaacggga gtgtttgtgg cttaataatg aagccacgcg gtacggtggc gctccggcta
    70441 tatcggttaa gaagatgaca ccctcaccag agtccgcttc atgcagagca tcgcacatca
    70501 tgcggctgag catattagag cttaacccac gccagaaatt cacggcccgg cactgaagaa
    70561 gcgccccatg ttttttctcc agcgcatcca gtatctcttg cgcccggtca tcgtgacagg
    70621 taattaccca acctaacatc gccttcctcc ttagccgaaa atcagtctac cctgaccatt
    70681 gttgataaag ggtgatagcc gtcaaaactc ctctccccca aatccagagg agaggaaata
    70741 gccttagcta cgcaaaccac gtccacgttg gatcagcgac caacagatca aataaaacgc
    70801 cacaataaag accaccagta cgccaaaggt agtgaccagc ggaacatcat tgataccgag
    70861 gaagccgtag cggaaaccac tgatcatata aacgattggg ttcaggtgcg acagcccttg
    70921 ccagaacggc ggcaacaaag tcagtgagta aaagacccca cccaaatacg tgagtggcgt
    70981 taacacaaag gttggcacca ggctgatgtc atcgaacgtt ttggcaaaca cgccgttcag
    71041 caaacccgca agggagaata gcaccgccgt gagcaccagg gttaaggcaa cgaataccca
    71101 cgaatgcacc tgaaacggca caaaaaacag tgaaattgcc gtcaccagaa tgccaacaaa
    71161 cagaccacgc gccacgccac cgccgacata tccggcaata atgacgtgag tcggaaccgg
    71221 cgctaccagc agctcttcaa tattacgctg gaacttggca ccaaaaaatg atgacgcgac
    71281 gttagcgtag gcattggtga tcaccgacat catgatcagc cccggtacga tgaactgcat
    71341 atagctgaag ccatgcatat cgccaatacg cgaacctatc aggttaccga agataataaa
    71401 gtaaagggtc atggtgatga ctggcggcac cagcgtctgc acccagatac gcataaagcg
    71461 atggatctct ttcgcccaga tgctttttag cgccacccag taaagatgca tcatgcgcga
    71521 tctccttgtt tttcattaac cagtgaaaca aacagctctt ccagacggtt agctttgtta
    71581 cgcatactta atacctgaat gccctgctca cttaactgcg taaatacgct gttgatcccc
    71641 tgctcacgca gcacttcaac ttccagcgtc gcggtatcga ccagtcgata ctgatagcca
    71701 tcgagcttcg gtaacggact tttcggtgcg agatcgagaa taaaggtttc cgatttcagc
    71761 ttagccagca gcgccttcat cgaggtattt tccaccagct caccgtgttg aataatgccg
    71821 atattgcggc acagcatttc tgcttcttcc aggtagtgtg tggtgagaat gatggtggtg
    71881 cctttgtcgt ttaaatcctt caaaaagccc cacattgagc ggcgaagttc aatatccacg
    71941 cctgcggtcg gttcgtcgag aatcagtagt ttaggttcat gcattaacgc acgggcaatc
    72001 attaaacggc gcttcatccc gccagataac atacgcgcac gttcgttgcg ttttccccat
    72061 agatcgagtt gtttaagata tttttcgctg cggatgtacg cctctttgcg ctccacaccg
    72121 tagtaccctg cctgatttac cacaatttgc tgcacggttt caaacgggtt gaagttaaat
    72181 tcctgcggca ccagtcccaa ctgacgttta gcgttcacga catctttctc gagatcgtaa
    72241 ccaaatacgc tgacccgccc ggaggtttta tttaccagag agctgataat accgatagtg
    72301 gtcgatttcc cggccccgtt cggcccgaga agcgcataaa aatcacccgc ttcgacctgc
    72361 aaatctattc cacgaagcgc ctgaacgccg cctggataag tttttttaag ctgttgaagt
    72421 tccagtgcaa tggtcataaa tttttactta ccttacgttc ttacacttta tctgtggttt
    72481 aaatcgtccc ggagttgccc tatattagcc aaacgtaatt atttggttac aggtcgttaa
    72541 cctccatgaa agacatagat acactcatca gcaacaatgc actatggtca aaaatgctgg
    72601 tggaagagga tcccgggttt tttgagaaac tggcacaagc gcaaaaaccg cgctttctat
    72661 ggattggatg ttccgacagt cgcgttcctg cagaacgttt aaccggtctt gagccgggcg
    72721 aactctttgt tcaccgtaat gttgctaacc tggtcattca caccgacctg aactgccttt
    72781 ccgtggttca gtatgcagtg gatgtactcg aagttgaaca cattattatc tgtggccact
    72841 acggttgcgg cggcgtacaa gccgccgttg aaaacccgga actggggctt atcaacaact
    72901 ggctgctgca tatccgcgat atctggttca aacatagctc attgctcggc gaaatgccgc
    72961 aagagcgccg tctggatacc ttgtgtgaac tgaacgtcat ggaacaggtg tataacctgg
    73021 gccactccac cattatgcaa tcagcgtgga aacgcgggca gaaagttacc attcacggct
    73081 gggcctacgg cattcacgac ggcttgctgc gtgatctgga tgttaccgcc accaaccgcg
    73141 aaacccttga gcaacgttac cgtcacggga tttccaacct caagctgaaa cacgccaacc
    73201 acaaataaaa atgccatgcc ggatgcaaca catccggcaa cttcacactt actcgtccag
    73261 cagaatcact ttgccgatat acggcagatg acggtaacgc tgtgcgtaat caatgccgta
    73321 acccaccaca aactcatccg ggatcgagaa accgataaat tctaccggga cgttcacttc
    73381 acgacgggac ggtttatcca gcagcgtaca aatcgccagc gacttcggtt cgcgcaggct
    73441 taagatctca cgcactttcg acagtgtatt ccccgagtcg atgatatctt caacaatcag
    73501 cacgtccttg ccacggatat cttcatccag atctttgagg attttcacat cacgggtggt
    73561 ggacatgccg ctaccgtagc tggaggcggt cataaagtcg acttcatgag atacctgaac
    73621 ttcacggcac aggtccgcca taaacataaa tgagccacgc agcagaccca ccagcaccat
    73681 atcgctgccg ctgtctttgt aacgctcagt aatctgacga cccagttcgg cgatacgcgc
    73741 tttaatctcc gcttcgggga tcattacttc tacagtatgt ttcatatctc taaccatatg
    73801 atttaaaaac aaatcacttc gcacgggcag gttttggcac cgcaacaaag cgcaagacac
    73861 gcagtatacc agtaaaacta ttcattcgcg gaatctgtta ataaagctcg aattgtgatg
    73921 acgatcacac atgttaaaac ctataattaa ttgctactaa aatattaatg aattgaaatg
    73981 gtgtctcttt atggcaatta acaatacagg ctcgcgacga ttactcgtca cgctaacagc
    74041 cctttttgca gcgctttgcg ggctgtatct actcattggc ggaggctggc tggtcgcgat
    74101 tggcggctcc tggtactacc ctatcgctgg ccttgtgatg ctcggcgtcg cctggatgct
    74161 gtggcgcagt aaacgtgccg cgctttggct gtacgcagcc ctgctgctcg gcaccatgat
    74221 ttggggcgtc tgggaagttg gtttcgactt ctgggcgctg actccgcgca gcgacattct
    74281 ggtcttcttc ggcatctggc tgatcctgcc gtttgtctgg cgtcgcctgg tcattcctgc
    74341 cagcggcgca gttgccgcac tggtggtggc actgctgatt agcggtggta tcctgacctg
    74401 ggccggattt aacgatccgc aggaaatcaa cggcacctta agcgccaatg ccacacctgc
    74461 ggaagctatc tcacccgttg ccgatcagga ctggcctgcc tatggtcgca atcaggaagg
    74521 tcaacgcttt tcacctctga aacaaattaa cgccgataac gtccataatc tgaaagaagc
    74581 ctgggtgttc cgtactggcg atgtgaagca gccgaacgat ccgggcgaaa tcaccaatga
    74641 agtgacgccg attaaagtgg gcgacaccct ttacctgtgt accgctcacc agcgcctgtt
    74701 tgcgctcgat gccgccagcg gcaaagagaa atggcattac gatcctgagc tgaaaactaa
    74761 cgagtctttc cagcacgtaa cctgccgtgg cgtctcttat catgaagcca aagcagaaac
    74821 ggcttcgccg gaagtgatgg cggattgccc gcgtcgtatc attcttccgg tcaatgatgg
    74881 tcgactgatt gcgattaacg ctgaaaacgg caaactgtgc gaaaccttcg ccaataaagg
    74941 cgtgctcaat ctgcaaagca atatgccaga caccaaaccg ggtctgtatg aaccgacttc
    75001 gccaccgatt atcaccgata aaaccatcgt gatggccggt tcagttaccg ataacttctc
    75061 aacccgcgaa acgtctggcg tgatccgtgg ttttgatgtc aacaccgggg agctgctgtg
    75121 ggcttttgat cccggcgcga aagatccgaa cgcaatcccg tctgacgaac acacctttac
    75181 ctttaactcg ccaaactcct gggcaccagc ggcctatgac gcgaagctgg atctggtcta
    75241 tctgccgatg ggcgtgacca cgccggatat ctggggcggt aaccgcacac cggaacagga
    75301 acgttatgcc agctcgattc tggcgctgaa tgccactacc gggaaactgg cgtggagcta
    75361 ccagaccgtt caccacgacc tgtgggacat ggatcttccg gcacagccga cgctggcgga
    75421 catcaccgtt aatggtcaga aagtgccagt tatttacgct ccggcgaaaa ccggcaacat
    75481 ttttgtgctc gatcgtcgca atggcgaact ggtggttccg gccccggaaa aaccggtgcc
    75541 gcaaggtgct gcgaaaggcg attacgttac tccgacccag ccgttctctg aactgagctt
    75601 ccgtccgaag aaagatttga gcggtgcgga tatgtgggga gccaccatgt ttgaccaact
    75661 ggtgtgccgc gtgatgttcc accagatgcg ctatgaaggc attttcacgc cgccatctga
    75721 acagggcacg ctggtcttcc cgggtaacct gggaatgttt gaatggggcg ggatttccgt
    75781 tgatccaaat cgtgaagtgg caattgccaa cccaatggca ctgccgtttg tttcgaaact
    75841 gatcccacgc ggtccgggta acccgatgga gcagccgaaa gatgccaaag gcacgggtac
    75901 ggaatccggc attcagccac agtacggtgt accgtatggt gtcacgctca acccgttcct
    75961 ctcaccgttt ggtctgccgt gtaaacagcc agcatggggt tatatctcgg cgctggatct
    76021 gaaaaccaat gaagtggtgt ggaagaaacg tattggtacg ccgcaagaca gtatgccgtt
    76081 cccgatgcct gtaccggtgc cgttcaatat gggtatgccg atgctgggcg ggccaatctc
    76141 cacggcgggt aacgtgctgt ttatcgctgc tacggcagat aactacctgc gcgcttacaa
    76201 catgagcaac ggtgaaaaac tgtggcaggg ccgtttacca gcgggtggtc aggcgacgcc
    76261 aatgacctat gaagtgaatg gcaagcagta tgtggtgatc tccgcaggcg gtcacggttc
    76321 atttggtacg aagatgggcg actatattgt ggcttatgcg ctgccggatg atgtgaaata
    76381 accataatgc ccggagagat ccgggcatat ttccgaatac ggtcttttta taccgtaaac
    76441 cctaacatca tccccgtatc ttcatgctcc agcagatggc agtgcgccat ataagcatgt
    76501 tctttcggtg cgttgtgatt aaacttcacc agcacttcac tgacattgcc ttctacctta
    76561 acggtatctt tccagcccgc gcgatgagcc gctggcggtt tgccattttc tgacaagata
    76621 cggaactggg tgccgtgaat atggaacgga tgcagcatca tgtcgcccac gccagagata
    76681 acccaacgtt cgtactgccc tttcgccgcc gcaaacatcg gcttattcat atcaaacgcc
    76741 tgaccgttga ttttattggc atggtggaaa tcgaacttcc cgccatggtt catatgattc
    76801 atattgccgt gccccatatg gcccatcatc tggctatgat ccatcccggc catcgcctga
    76861 tcgccatatt tctccatcag catctgcatc cccatcatat cgagcatcgg gtccatagaa
    76921 agttgcagct tgcgtaccgt cagcccttcc agcgaaggta acgcaggcag gctacttaat
    76981 gtgtctggca aagcaccgga ggcactaata gcaatcggct gaatccgcat taccggatgc
    77041 ggcttgtcaa acggcgcaat cgccatcccc atctggctga ccggtagcgt caccaggtca
    77101 aagggtttgt tgtcgttaac ctccaccagc acttcaaaac gctcgcccat cagcaccggc
    77161 agctcgctca ccttcaccgg ttcaggtagc agaccaccgt cgctggcaat cacatacaac
    77221 gggcgattgt cgctggtggc gaaattgagc gagcgggcat tacagccatt gagcaaacgc
    77281 aggcgcagcc aaccacgtgg ggcagcgtgt tgtgggtaga ttgcaccgtt ggtcagcagc
    77341 gtatcgccaa accagcccac ggcggcggtc atcacatcca gttgataatc aatctgccca
    77401 tcagcgttaa attttttatc ctgaacaatc accggaacat catcgatacc ccactgtttt
    77461 ggcagcatta atttcaggat ctcgtcatct tcaattacca ccagcccagc caaccccatc
    77521 gccacctgtc gcccggtctt gccatgttga tgtggatgga accagcaagt agcggcaggt
    77581 tgatcaacgt tcaacgtcac cgagcgcttg ccacctggcg gaataattcc ctgcgggccg
    77641 ccgtcgactt cacccggtac ttccagcccg tgccagtgca acgtcgtctc ttccgtcagt
    77701 tggttataga tatcaaccgt taccgctttg ccgcgctgta atttcaccgc cggccccagc
    77761 agattgccgt tatagcccca ggtagttgca gttttctcgc caaaggtaga ctgacctgcg
    77821 ccaatagtta actgaatgcg attacgggca tcggtcgtga gcaaatcagg gatcggtaac
    77881 gttgggcgtt ccgccgcaaa gactgcgcgg ctccacagcg gcaaggctga agccacaccc
    77941 agcgcgacgg aatattttaa gaaatcacga cgttgcatag ttatttcctt attcttaagc
    78001 aggcgaaaca aaatcaaacg ttgagcatag tccttcccct tacgggaagg tcaagccgca
    78061 gacacaattt aatcgacaat aatggtcgtc gcctcgctcg cagtgtgcta acgtttatct
    78121 tctttaagcc cctggtagaa gcaatgaaga cgtttttcag aacagtgtta ttcggcagcc
    78181 tgatggccgt ttgcgcaaac agttacgcgc tcagcgagtc tgaagccgaa gatatggccg
    78241 atttaacggc agtttttgtc tttctgaaga acgattgtgg ttaccagaac ttacctaacg
    78301 ggcaaattcg tcgcgcactg gtctttttcg cccagcaaaa ccagtgggat ctcagtaatt
    78361 acgacacctt cgacatgaaa gccctcggtg aagacagcta ccgcgatctc agcggcattg
    78421 gcattcccgt cgctaaaaag tgcaaagccc tggcccgcga ttccttaagc ctgcttgcct
    78481 acgtcaaata atccctgata cctttttgta gaaatattga ccgtgcatcc gcggtcaatg
    78541 ttagctatta tgttgcgccc tttttttacg ggtgttaaca aaggaggtat caacccatgg
    78601 ccgaaaaaaa acagtggcat gaaacgctac acgaccagtt tgggcagtac tttgcggtag
    78661 ataacgttct gtatcatgaa aagaccgatc accaagatct gatcattttt gagaacgctg
    78721 catttggtcg cgtaatggcg ctggatggcg tagtacaaac caccgagcgc gacgagttta
    78781 tctatcatga gatgatgacc catgttccgc tactggccca cggtcacgcg aaacatgtgc
    78841 tgattatcgg cggcggcgac ggtgccatgc tgcgtgaagt aacccgacat aaaaacgttg
    78901 agtcaatcac gatggtggaa atcgatgcgg gtgtcgtatc gttctgccgt cagtatctac
    78961 ccaaccataa cgccggtagc tacgacgatc cgcgctttaa gttggtgatc gacgatggcg
    79021 tcaatttcgt taatcaaacc agccagacct ttgatgtcat tatctccgac tgcaccgatc
    79081 ctatcggtcc cggcgaaagc cttttcactt cggcatttta tgaaggctgc aaacgttgcc
    79141 tgaatcctgg cggtatcttc gtcgcacaaa acggcgtctg ctttttacag caggaagaag
    79201 ccatcgacag ccatcgcaaa ctcagccatt acttcagcga cgttggcttt tatcaggcgg
    79261 cgattccgac ctattacggc ggtatcatga cttttgcatg ggcgacagat aacgacgcct
    79321 tacgccatct ctcaaccgaa attattcagg cgcgttttct cgcttctggc ctgaaatgcc
    79381 gttattacaa tccggcaatc catacggcag cttttgcctt acctcagtat ctgcaagacg
    79441 cactggcttc acagccgtcc taaggagaag ataagaaatt gaaaaaactg aaactgcatg
    79501 gctttaataa tctgaccaaa agtctgagtt tttgtattta cgatatctgc tacgccaaaa
    79561 ctgccgaaga gcgcgacggt tatattgctt atatcgatga actctataat gccaaccgtc
    79621 tgaccgaaat cctgtcagaa acctgttcca ttatcggggc caatattctt aacatcgccc
    79681 gccaggatta cgaaccacag ggtgccagcg tcactattct ggtgagtgaa gaaccggtcg
    79741 acccgaaact tatcgacaaa acagaacacc ccggcccact gccagaaacg gtcgttgccc
    79801 atctcgataa aagtcatatt tgcgtacata cctacccgga aagtcatcct gaaggcggtt
    79861 tatgtacctt ccgcgccgat attgaagtct ctacctgcgg cgtgatttct ccgctgaagg
    79921 cgctgaatta cctgatccac cagcttgagt ccgatatcgt aaccattgat tatcgcgtgc
    79981 gcggttttac tcgcgacatt aacggtatga aacactttat cgaccatgag attaattcga
    80041 ttcagaactt tatgtctgac gatatgaagg cgctgtatga catggtggat gtaaatgtct
    80101 atcaggaaaa tatcttccat accaagatgt tgcttaaaga gttcgacctt aagcactaca
    80161 tgttccacac caaaccggaa gatttaaccg acagcgagcg ccaggaaatt accgctgcgc
    80221 tgtggaaaga aatgcgcgag atttattacg ggcgcaatat gccagctgtt taacgtctcg
    80281 ggcggagctc ccaggctccg ccagatttat ttacttctgc tgcacgaaat tacggtaagc
    80341 cgccacgacc tgcagaaaat cctcaacgcc gcatagcgac aggctttctt cgtcgtagta
    80401 gttcatcccc tcttccattt catcgccagc gaattccagt tgattggcgc gaacaatcac
    80461 ctcttcaccg tccatccaca gagtgtactc atgccctgcc cgctgccagg aacgttcgct
    80521 acctttcagt gcgtgcgccg cttgttccac ttcatcaagc aaggccaggt tttctttcac
    80581 ctcttcatta aaccagtgcc cgaccacttc atgccccatg gacatacgca cctttacaac
    80641 tccggtaata tcgcgcagaa attcgtaatc catagtgtgt tcctctgctc ccggcaatgc
    80701 gccgaaatcg cattgcgcca ttgatgtaat tatcgcagcc ttaccggaga aaaacagcgg
    80761 aacggcgatg gtttagaaat aaaaaaatgc ccgggaatct cattcaccgg gcattgtgtc
    80821 gtttatgcgc agcgcgtgcg cttacttatt acaccgcagt ctggaaaatc accccatcgg
    80881 ctttttcggt gtactgagaa agctggttga agttcagata acgataagta tcaacggcag
    80941 ttttatctac ttgcgccacg taggtctggt actcttccgg cgtcggcagt ttgccaatca
    81001 gcgccgcaac aaccgccagt tccgcagaag ccaggaagac attcgcgcca gtacccagac
    81061 ggttcgggaa gttacgggta gaggtggaaa ccaccgtcgc accgtctgtt acacgcgcct
    81121 ggttacccat acacagggaa cagccaggga tctcgatacg cgcaccactc ttaccgaaga
    81181 cgctgtagta gccttcttca gtcaactgcg cggcgtccat acgggttggc ggtgccaccc
    81241 acaggcgggt cggcagttgg cctttgtgcg catccagcag tttacccgca gcacggaagt
    81301 gaccgatgtt ggtcatgcag gaaccgataa atacttcgtc gatcttctca ccctgtaccg
    81361 cagacagcgg acgcgcgtca tccgggtcgt tcggtgcaca gaggattggc tctttaatat
    81421 ccgccagatc gatgtcgatc actgccgcgt attcagcatc tgcatcggct tccagcagct
    81481 caggattcgc cagccatttt tccatgccct gaatacgacg ttccagggtg cgacgatcgc
    81541 cgtaaccttc cgcgatcatc cacttcagca ggacgatgtt agagttcagg tattcgatga
    81601 tcggttcttt gttcagcttg atggtacaac cagcggcaga acgctcggcg gacgcatcgg
    81661 tcagttcaaa tgcctgctca actttcagat ccggcagacc ttcaatttcc aggatgcggc
    81721 cagagaagat gtttttcttg cctttcttct caacggtcag cagaccttgt ttgatcgcat
    81781 acagcggaat ggcatgtacc agatcgcgca gggtgatgcc cggctgcatt ttgcctttga
    81841 agcgcaccag aacggattcc ggcatatcca gcggcattac gcctgttgcg gctgcaaatg
    81901 ccaccagacc agaacccgcc gggaaagaga taccgatcgg gaaacgggta tgggaatcac
    81961 caccggtacc gacggtatcc ggcagcagca tacggttcag ccaggagtga atgacgccgt
    82021 cacccggacg cagcgacaca ccgccacggt tcataatgaa gtccggcagc gtgtggtgcg
    82081 tgttcacgtc aactggcttc ggatacgccg cggtgtggca gaaagactgc atcaccaggt
    82141 cagccgagaa gcccaggcac gccaggtctt tcagttcatc acgggtcatc gggccggtgg
    82201 tgtcctggga acctacagaa gtcattttcg gttcacagta cgcgcccgga cgaatgcctt
    82261 tcacgccaca ggcacggcct accatttttt gcgccagcga gaagccgcga tcgctctcag
    82321 cgacatcttt cgcctgacgg aacacatcac tgtgcggcag accaagtgct tcacgcgctt
    82381 tggtggtcag gccacgcccg ataatcagcg gaatacggcc accagcacgc acttcatcaa
    82441 tcagcacgtc ggttttcagt tcgaaggtcg ccagcagttc gccggtttcg tggttacgca
    82501 cttcaccttt gtacgggtaa acgtcaatca cgtcgcccat gttcaggtta gagacgtcga
    82561 cttcgattgg cagtgcaccc gcgtcttcca tcgtgttaaa gaagatgggt gcaattttac
    82621 cgccgaggca caaaccaccg ccgcgtttgt tcggcacatg tggaatatca tcgcccataa
    82681 accacagaac ggagttagtg gcggatttac gcgaagaacc cgtacccaca acgtcaccga
    82741 cgtacgccag cgggaaacct ttctgttgca gagcttcgat ttgcttgatc ggaccaacaa
    82801 caccaggctg gtctggctca ataccttcac gggcgttttt cagcatcgcc agcgcgtgca
    82861 gtgggatatc cgggcgtgac cacgcatccg gtgccggaga aaggtcatcg gtgttagttt
    82921 cgccagtgac tttgaagacg gtaacggtca gtttttcagc cagcgccggg cgattcagga
    82981 accattcggc atccgcccag gactgcataa cctgcttcgc atattcgttg cctgctttcg
    83041 ctttctcttc tacgtcatag aagttatcga acatcagcag cgtgtgagaa agtgctttgg
    83101 cagcaatagg tgccagtttg gcatcatcca gcgcgtcgat cagcggatga atgttgtaac
    83161 caccctgcat ggtgcccagc agttcgatgg ctttttccgg agtcagcaga ggggatttgg
    83221 cttcgccttt cgcgatagca gccaggaagc ctgctttgac ataggcggct tcatcgacgc
    83281 ctgggggaac acggttggtt aacagatcta acaggaattc ttcttcgccc gcgggcgggt
    83341 ttttcagcag ctctacaagt gcggccattt ggtttgcatc caggggtttg ggcgcaatcc
    83401 cctcagcggc acgctcagct acgtgcttac ggtattcttc tagcacgacg gttctcctcg
    83461 ctctcattgt catagtgcgg caggcgattc tcttcacgct cctgtgagac agcagtttgt
    83521 agggtaaatg cccagtaccg caacgggcag aatagcagga ttttgacgat gtgttaatct
    83581 gtttacaaaa aagcaacata aaaaagtggc tgaatcgtta aggatggtct agagattgtt
    83641 tccctccgta aaaacttcgt taattcgcat ggtgataatc acctttctca acgaatccca
    83701 agattagtca aaatttaaac taccgcctct ttatactcgg attcacagca cctgcgggtg
    83761 gcagttcgcc gaccattgcg atttccttga gatccgaatt atgaaaatga ctttgccgtt
    83821 taaaccccat gtgctggcgc taatttgcag tgccgggctt tgtgccgcct ctaccgggct
    83881 atatataaaa agccgcacag tggaagcgcc tgtggaaccg caatcgacac aacagactgc
    83941 gcctgacatc accgcagtta cgcttcctgc aacggtttcc gcaccgcccg taacgcccgc
    84001 cgtcgtcaaa tccgcattca gcactgcaca aatcgatcaa tgggttgcgc ctgtcgcgct
    84061 gtaccccgat tctctgcttt cacaagtgtt aatggcatca acctatccgg caaacgttgc
    84121 tcaagcagtg caatggtcgc acgataatcc acttaaacaa ggcgatgctg ctattcaggc
    84181 ggtatctgac cagccgtggg acgccagcgt taaatcactg gtggcctttc cacaattgat
    84241 ggcattgatg ggcgaaaacc cgcaatgggt gcaaaacctg ggcgatgctt ttctggcgca
    84301 gccgcaggac gtgatggact cggtacagcg attgcggcaa ctggcgcaac aaaccggttc
    84361 gctgaagtca tcaaccgaac aaaaagttat taccacaacg aagaaagctg taccggtaaa
    84421 acagacagtc acggcacccg tcataccatc caataccgtt ttaactgcca gccccgtcat
    84481 tacagagcct gcaacaaccg tcatttccat tgagcccgcc aatcctgatg tggtctatat
    84541 tcccaactac aacccaaccg tggtttacgg gaactgggcc aatactgcgt atccgccggt
    84601 ttatctgcca ccaccagccg gagaaccgtt tattgacagc tttgtgcgcg gattcggcta
    84661 tagcatgggt gttgctacca cgtacgcact attcagcagc atcgactggg atgacgacga
    84721 tcatgaccat catcatcatg acgatgatga ttatcatcac cacgatggcg gtcatcgtga
    84781 cggtaatggc tggcaacaca acggcgacaa catcaatatc gacgtcaaca atttcaaccg
    84841 tatcaccggt gagcatctta ctgataagaa tatggcatgg cggcacaatc caaactaccg
    84901 taatggtgtg ccctatcatg atcaggatat ggcaaagcgg tttcatcaaa ccgatgtcaa
    84961 cggcggaatg agcgccacgc agctacctgc tccaacacgc gacagccagc gtcaggcggc
    85021 agcaagtcag tttcagcaac gaacacacgc cgcccccgtc attacacgag atacccaacg
    85081 tcaggcagcg gcacagcggt ttaatgaagc tgaaaactat gggagctatg acgacttccg
    85141 cgacttcagc cgtcgccaac cactgaccca gcaacaaaag gacgccgctc gtcagcgtta
    85201 tcagtcggcc tcgcctgagc agcgccaggc agtccgcgag aaaatgcaga ctaacccaca
    85261 gatccagcag cgaagagacg cagcgcgtga gcgtattcag tcagcctcgc ctgagcagcg
    85321 ccaggtgttt aaggaaaaag tacagcagcg cccactgaac caacagcaac gtgataacgc
    85381 ccgccagcgt gttcaatcag catcacctga acaacgtcag gtttttcggg aaaaagttca
    85441 ggagagccgc ccacaacgtc taaacgacag taaccatact gtcaggctga ataacgagca
    85501 acggtcagca gtacgcgaac gtctctctga gcgcggagca aggcgacagg aaaggtaaat
    85561 tgcagacgta aaaaaagcgg cgtggttagc cgctttttta attgccggat gttccggcaa
    85621 acgaacaatt acttcttctt cgctttcggg ttcggcaggt cggtaatgct accttcgaac
    85681 acttctgccg ccaggcccac agactcgtgc agagtcgggt gcgcgtggat ggtcagtgcg
    85741 atgtcttcag catcacaacc catttcgatt gccaggccga tttcacccag cagctcgccg
    85801 ccgttggtac cgacaatcgc accaccgatc acacggtgag attctttgtc gaaaatcagc
    85861 ttggtcatac cgtctgcgca gtcggaagcg atagcacgac cagaagcagc ccacgggaag
    85921 gtggcggttt catagctgat gcctttctct ttcgcttctt tctcagtcag acctacccat
    85981 gcaacttctg gttcggtata ggcgatggac gggataactt tcggatcgaa gtagtgtttc
    86041 ttaccggcga taacttcagc ggcaacgtga ccttcgtgaa cacctttgtg tgccagcatc
    86101 ggctgaccga cgatatcgcc gatagcaaag atgtgcggta cgttggtacg cagctgtttg
    86161 tcaacgcgga tgaaaccacg gtcgtccact tccacgccag ctttgcctgc gtcgaggttt
    86221 ttaccgttcg gcacacgacc aatcgctacc agcacggcgt cgtaacgctg cggttcagcg
    86281 ggtgcttttt tgccttccat cgtcacataa ataccgtctt ctttcgcttc aacggcggta
    86341 actttggttt ccagcatcag gttgaatttc ttgctgatac gcttggtgaa gactttaacg
    86401 atgtctttgt cagctgccgg gataacctgg tcgaacattt caaccacgtc aatctgtgaa
    86461 cccagcgcgt ggtatacggt gcccatttcc agaccgatga taccgccacc cattaccagc
    86521 aggcgttctg gtacttcttt cagttccagc gcgtcagtgg agtcccagat acgcggatct
    86581 tcatgcggaa taaacggcag ttggatcggg cgagaacccg ctgcaatgat cgcattgtcg
    86641 aagttgatca cggttttgcc gttctcacct tcaacttcca gggtgttagc cccggtgaat
    86701 ttacccagac cgttgaccac tttgactttg cggcctttcg ccataccagc cagaccaccg
    86761 gtcagctgat tgatcacttt ctctttccag gtacgaatct tgtcaatatc ggttttcggt
    86821 tcgccgaaga cgataccgtg ttcagccagc gctttggctt cttcgataac ttttgctacg
    86881 tgcagcagtg ctttagaagg gatacagccg acgttcaggc aaacaccgcc aagggtgttg
    86941 taacgttcta cgattacggt ttccagacct aaatcagcgc aacggaaggc agcggagtaa
    87001 cctgcggggc ctgccccaag taccacgacc tgagttttga tttcagtact catcatgacc
    87061 tctatatatt tatctccggc ggtcataccc gtcgtctttc aggccgcagc ggcgttagct
    87121 tcacgccctc accccagtca cttacttatg taagctcctg gggattctgg cgcttgctac
    87181 cttgctgcac ccagaaatcc atagggtatg tgaagtaata ccctaaccac caccgggtcg
    87241 ttctatccgt cggtatttta caaaattgtt aacaattttt aaacaacaaa cggcaaccga
    87301 tttgtctatt cgctaataac ctcaatacat tcatgagatt accagaaaaa agccggccgt
    87361 tgggccggct cttttactta catcaccaga cggcgaatgt cagacagcgt gttgttaatg
    87421 atggtaatga aacgggcacc atcagcaccg tcgatcacgc ggtggtcgaa ggagagagaa
    87481 atcggcagca tcagacgcgg cacgaactct ttaccattcc acaccggctc catcgcggac
    87541 ttggaaacgc cgaggatagc cacttccggc gcgttcacaa tcggcgcgaa gtgggtagta
    87601 cccaggccgc cgatgctgga gatggtgaag caaccgccct gcatttcgcc cgcagtcagc
    87661 ttaccgtcac gcgctttctt agaaatagtc atcagctcgc gagacagctc gatgatgcct
    87721 ttcttgttga cgtctttgaa taccggaaca accagaccgt tcggggtatc caccgccaca
    87781 ccgatgttga tgtatttctt cagggtcaga cgctgaccgt cttccgacaa cgaactgttg
    87841 aagcgaggca tctgctcaag agctgcagca acggctttca tgatgaagac aaccggggtg
    87901 atcttcacat ccagcttacg tttcgccgct tcttcgttct gctgtttacg gaacgcttcc
    87961 agctcggtga tatcggtttt gtcgaagtga gtaacatgcg ggatcatcac ccagttacgg
    88021 ctcaggttcg caccagaaat tttctggata cggcccagtt ccacttcttc gatttcacca
    88081 aacttgctga agtccacctt cggccacggc agcatgcctg ggataccgcc gccagtcgcc
    88141 gccggagctg cttctgcacg tttgatagct tctttcacgt aagcctgaac gtcttcgcgc
    88201 aggatacgac ctttacggcc agtgcccttc actttcgcca ggttaacgcc aaactcgcgt
    88261 gccagacggc ggatcagcgg agtcgcgtga acgtaagcgt cgttttctgc aaattcagat
    88321 ttgccttccg ctttcgcagc cggtgctgct gccggagctt cagcttttgc tgccggagcc
    88381 ggcgctgccg cttcctgttt cgcaggagct gccgcaggcg ctgcgccttc aacttcgaag
    88441 atcataatca gcgagccagt tttcacttta tcgccaacgt tgactttcag ttccttcacg
    88501 acgcctgcaa acggagccgg gacttccata gaagctttat cgccttctac ggtgatcagt
    88561 gactgttcag cggcaatttt gtcgcccact ttcaccatca cttcggtcac ttcaacttcg
    88621 tcaccgccga tatccggaac gttaacttct ttcacgccag ccgctggtgc aggggccgct
    88681 gccggagccg cttcctgttt agccgccgga gctgccgcgc ctgcttcacc cgcgacttcg
    88741 aagaccataa tcagcgagcc ggtagacact ttgtcaccca cgttcacttt gatctctttc
    88801 acggtgccag caaacggagc cggaacttcc atagaagctt tatcgccttc tacggtgatc
    88861 agcgactgtt cagcttcaac tttatcgcca actttcacca ggatttcggt cacttcaact
    88921 tcgtcgctgc cgatatccgg aacgttaacg tcttttgccg ctgcagccgc tggtgctgct
    88981 gccggagctg tttctttctt ctcttctgcc tgagcaggtg cagcgtctgc tgcaccgtcg
    89041 gcggaatcga aaatcataat cagtgcgccg gtctgggttt tatcgccaac agagactttg
    89101 atctctttaa cgatacccgc ctgcggagac ggaacttcca tagaggcttt gtcgccttct
    89161 acggtgatca gcgactgttc ggcttcaact ttgtcgccca ctttgaccag gatctcggtg
    89221 atttcaactt catcagcccc gatgtccggt actttgattt cgatagccat tattctttta
    89281 cctcttacgc cagacgcggg ttaactttat ctgcatcgat gttgaatttg gcgattgcgt
    89341 cagcaaccac tttcttatcg atttcgccac gtttagccag ttcgcccagc gccgctacaa
    89401 ccacgtagga agcatcaact tcgaagtggt gacgcaggtt ctcacggctg tcggaacgac
    89461 cgaagccatc agtacccagt acgcggtagt cgtcagccgg tacgtaagta cggacctgct
    89521 cagcgaacag tttcatatag tcggtagatg ccactgccgg agcgtcgttc atcacctgag
    89581 cgatatacgg aacgcgcgga gtttccagcg ggtgcagcat gttccagcgt tcacaatcct
    89641 gaccatctcg cgccagttcg gtgaaggagg tcacgctata aacgtcagaa cctacgccgt
    89701 aatctttcgc caggatctct gccgcttcac ggacgtgacg caggatggaa ccggagccca
    89761 gcagctgaac tttacctttg ctaccttcaa tggtttcgag tttgtagata cctttacgga
    89821 taccttcctc agcaccttcc ggcattgccg gcatgtggta gttttcgttc agcgtagtga
    89881 tgtagtagta aacgttctct tgtttttcac cgtacatacg ctccagaccg tcatgcataa
    89941 tgacagcaac ttcgtaagcg taagccgggt cgtaagagat acagttcggg atagtcagcg
    90001 actgaatgtg gctgtgacca tcttcgtgct gcagaccttc accgttcagg gtggtacgac
    90061 cggaagtacc gccgatcagg aagccacgcg cttgctggtc gccagccgcc cagcacagat
    90121 cgccgatacg ctggaagccg aacatcgagt aatagatgta gaacggaatc atcggcagat
    90181 tgttggtgct gtaagaggtc gccgctgcca gccaggaaca acctgcgccc aactcgttga
    90241 tcccttcctg cagaatctga cctttctcgt cttctttata gtaagcaacc tgctcgcggt
    90301 cctgcggggt gtactgctga ccgttcgggc tgtaaatacc aatctgacgg aacagacctt
    90361 ccataccgaa agtacgcgct tcgtcggcga tgatcggtac cagacgatct ttgatcgact
    90421 tgttcttcag cattacgttc agggcacgaa cgaaagcgat agtggtagag atctctttgc
    90481 tctgctcttc cagcagcgcg ccgaagtctt gcaggctcgg cagctcaagc ttctcggtga
    90541 agttcggctg acggcttggc agataaccgt gcagtttctg acgctgtgcg tgcagatagg
    90601 tatgctcttc agaaccttcc gggaaggtga tgtacggcag tttttcgata tctgcatcag
    90661 acaccggcac attgaaacgg tcgcggatgt gacgcacgcc gtccatgttc attttcttaa
    90721 cctggtgcgc gatgttttta ccttcagccg cgtcgcccat gccgtaacct ttaatggtat
    90781 gagcaaggat tactgtcgct ttgcctttgg tttcctgcgc tttcttgaat gcagcgtaga
    90841 ttttcttcgg atcgtgacca ccacggttca gtgcccagat ctgctcgtca gtccagtctg
    90901 caaccagtgc tgcggtttca ggatatttac cgaagaagtg ttcacgaacg tacgcaccat
    90961 ctttcgattt gaaggtctgg tagtcgccgt caacggtttc gttcatcagc tggatcagtt
    91021 taccgctggt atctttacgc agcagttcat cccaacggct accccacatc actttgatca
    91081 cgttccagcc agcaccttcg aagatgcctt ccagttcgtt gatgatcttg ccgttaccgg
    91141 tgaccgggcc gtcaagacgc tgcaggttac agttgataac gaagaccagg ttatccagtt
    91201 tttcacgggt agcgatggtg atcgcacctt tggattccgg ttcgtccatt tcaccgtcgc
    91261 cgaggaacgc gtaaacggtc tgtttagagg tatctttcag gccacggtgt tccagatatt
    91321 tcaggaattt agcctggtaa atagcaccaa tcggccccag acccatagat acggtcggga
    91381 actgccagaa ttccggcatc agtttcgggt gcggatagga agagaggcca ttgccgtgaa
    91441 cttcctgacg gaagttatcc agctgctcct gagtcagacg accttccagg aaagcacgag
    91501 cgtacacgcc cggggagatg tggccctgga agtaaaccag gtcgccgcca tcctgctcgt
    91561 tgcgtgcacg gaagaagtgg ttaaagcaca catcataaat ggttgcggaa gactggaagg
    91621 acgccatatg gccgcccagt tcgaggtctt ttttcgacgc acgcagcacc gtcatgatgg
    91681 cgttccagcg gatagctgaa cgaatacggc gttccagttc cagattaccc ggatactccg
    91741 gttgttcttc aacggggatg gtgttgatgt agttgctgat acctgtgcct gcggctacgt
    91801 ttacaccgcc tttgcgggct tcagcaagca gttggtcgat cagatactga gcacgctcaa
    91861 caccttcttc acggatgacc gattcgatcg cctggagcca gtcgcgagtt tcgatcggat
    91921 ccacgtcatt tgggaaacgt tctgacatgg gttattcctt atctatctaa taacgttgag
    91981 ttttctggaa cctgtcccat tgaactctcg ccggaaagct caataagaca ggttctacgt
    92041 ttagttgccg cgcttttata tgcgcttgat ttacaacatc ttctggataa tttttaccag
    92101 aaaaatcact aattctttcg ttgctccaga cgacgcagag aacgctcacg gcggctctct
    92161 tcacgacttc tgtcgagcaa aatttcttcg ataaaggcca gatggcgatg cgatgcttcg
    92221 cgcgcttctt ccggcttacc ggccataatc gcttcaaata tgcgggtgcg gtgactactc
    92281 accagcggca gcatctcgcg acgcgaatag agcaattcga agttctggcg gacattctgg
    92341 gccaacatcg gctccataca ccttagcaga tgaagcagaa ccacattgtg ggccgcttcg
    92401 gtgacggcaa tctgatactg gagtacggcg tttgattccg cgtccagatc gccagactgc
    92461 tgcgccagcc ctatggcgtg gtggagttca cggatgcgtt ccttgtcttc atcggtacta
    92521 cgcagcgcgg cgtaataagc ggcgatacct tccagggcgt gtcgtgtttc gagcaagtca
    92581 tactgtgact caggatggtc ggagagcagc tccaccagcg gatcgctgaa gctttgccat
    92641 aggctgctct ggacaaaagt gccgccaccc tggcgacgaa gcaacaagcc cttcgcttcg
    92701 agacgttgaa tcgcctcacg caaggaggga cgggagacgt caaactgttt tgccagttcg
    92761 cgttccggtg ggagtttttc gcccgggcgg agagtgcctt cgaggatcaa aaactccagt
    92821 tgctgctcaa tcacatcgga gagttttggt tggcggattt tgctgtaggc catgagttcc
    92881 tgtcttaagc cacttgccga agtcaattgg tcttaccaat ttcatatctg tgacgctaaa
    92941 gtaacaaagt attcacctta tgtccataca ggttttgatt gaaatcatga aactgtgcac
    93001 attttaacaa cttgacatat ataacgtttc aaagttgtaa ctatgcacaa atgtagactt
    93061 tacgtaggaa aggagttttt taacgattat taaactataa aaatccgaat tgaaccgatt
    93121 cacttaccaa ttttgtgatt tttaattcaa ttaaaacgaa tttaaattca ttctacatat
    93181 tgagaggggt tgaggctgag ctttacaaac ggtttctttt taagcaactc atcttcaacc
    93241 atgcataaag cgggtgcatt cgctgccgca taccattatt cttgatctga cggaagtctt
    93301 tttgtaacaa ttcaaacttc tttgatgtaa acaaattaat acaacaaacg gaattgcaaa
    93361 cttacacacg catcactgcg tagatcaaaa aaacaatcac cgcacgaggt ttcatgatgg
    93421 aaggtcaaca gcacggcgag cagctaaagc gcggccttaa aaaccgccat attcagctta
    93481 tcgcgctggg tggcgcgata gggacagggc tattcctggg tagcgcctcc gtaatacagt
    93541 ccgcagggcc agggattatc ctgggttacg ccattgctgg ttttatcgcc tttctgatca
    93601 tgcgtcagct gggtgaaatg gtggtcgaag aacctgtcgc aggctccttt agccactttg
    93661 cttataaata ctggggcagt tttgccggtt tcgcctctgg ctggaactac tgggtactgt
    93721 acgttttagt tgccatggct gagctgactg ccgtgggtaa atacattcag ttctggtatc
    93781 cggaaatccc cacctgggtt tctgccgccg tattctttgt ggtgattaac gccatcaacc
    93841 tgaccaacgt taaagtgttt ggcgagatgg agttctggtt tgccattatc aaagttatcg
    93901 cggtggtagc gatgatcatc ttcggcggct ggctgctatt cagtggcaac ggcggcccgc
    93961 aggcgaccgt tagcaacctg tgggatcagg gtggtttcct gccgcacggc ttcaccgggc
    94021 tggtgatgat gatggcgatt atcatgttct cgttcggtgg tctggaactg gtggggatca
    94081 ccgcagcaga agctgataac ccggagcaaa gtataccgaa agcaactaac caggttatct
    94141 accgcatcct gattttctat attggttcgt tagccgttct gctctcactg atgccgtgga
    94201 cccgcgttac cgccgatacc agtccgtttg tgctgatctt ccacgagtta ggcgatacct
    94261 ttgtggcgaa tgcgctgaac atcgtggtac tgactgcggc gctctccgtg tacaacagct
    94321 gcgtatattg caacagccgt atgctgtttg gtctggcaca acagggtaat gcgccaaaag
    94381 cgctggcgtc tgtcgataaa cgtggtgtac cagtaaatac cattctggtg tctgcactgg
    94441 taacggcgtt gtgcgtactg attaactacc ttgccccaga gtccgctttc ggactgttaa
    94501 tggcgctggt ggtatctgca ctggtaatca actgggcgat gattagcctg gcgcatatga
    94561 aattccgtcg cgccaagcag gaacaaggcg tggtaactcg cttccctgct ctgctttatc
    94621 cgctgggtaa ctggatctgc ctgctgttta tggcggcggt actggtgatt atgctgatga
    94681 ccccaggaat ggcgatttcg gtatacctga tcccggtatg gctgatcgtg ttaggtatcg
    94741 gctatctgtt taaagagaaa accgccaaag ccgtaaaagc gcattaatct ctctacgccc
    94801 tcacccgtac agggtgaggg caataatctt tacaccaacg ccccgtaaat cgtcagtagt
    94861 gcaatcacca ccacgaccac gaacgaggtt ttcttcgcca ttgaaaccgc tgccttcggc
    94921 gtctccacct tatcgacatg cggttcacgc gccagagaga actgcgccag acgcgttaac
    94981 acctgatact gcgaagtatg gaaatcaccc agcgaagcaa accaggccgg taacgctttc
    95041 tcaccatgac cgatcaaggc atataccaca cccgcaagac gaaccggcac ccaatccagt
    95101 acatgaagca cggcatcaat gccggactgt aaacgatgat gcggcgtctg atatcgcgcc
    95161 agccagtatt gccatgcacg caaaaacgca taccccatca gcgtaacggg tccccaggtt
    95221 ccccccacaa tcagccagaa cagcggtgca agataaaaac gaaagttaat ccacagcaat
    95281 gcattttgca gctcacgcaa atactcacgt tcgtcgcagc ctgccgggac gccgtgaatc
    95341 atggtgagtt cgccagccat cgtggcacgg gcatggctat cattacgtga agcagctgtc
    95401 agataagcat gataatgaag acgaacttta cctgcgccaa tacacagcaa accaatcagc
    95461 agccacacca gtagcgtggg aacgttgaac aatactccct gcaatgcgcg taacagtaaa
    95521 aaagtcacgc ccatcgcaat aatggtcatg cctaacgtgc gcccgagaga aaaatgtttc
    95581 acccgccgaa agaacgcttc aagacgatga tcaagctgcc agtgctcgcc caacttaaac
    95641 aggcgctcga aaattaacac cagtaaggtt gtaaatagcg tcatgttgtc tccttgctga
    95701 ccagcacacg aaaccgtgcc caatcaaatg caggaccggg atcggttttc cgatccggcg
    95761 caatatcaca atggcccgtc atgtttttag cgatatccgg atagcaatca atcagtgccc
    95821 gcgtaaccgc cgcaagctgt tgatactgcg catcggtata cgccagcgta tcggtgcctt
    95881 caagctcaat cccaatagaa aaatcattgc agcgttcgcg cccctgatac tgagagactc
    95941 ccgcatgcca tgcacgttta tcgaaaggaa catactggac tatttcacca tcacggcgaa
    96001 tcaaacagtg agcggagacg cgcaaatggg cgatctcagc aaagaaagga tgtgcctgcg
    96061 gatcaatagt tccagtgaat aatgcgtcga tccacggacc gccaaactcg cctggcggca
    96121 ggctaatatt gtgcaccacc agcagggtgg gtgtttcgtc atccgggcgg caatcgtaat
    96181 gtggtgaggg aacgcggcgc gcgccaacca gccacccctg ttctaacaac atgcaggatc
    96241 tccttatatg tggtgctaat acccggttca gagtagcatg tttctacctt atgattcgtt
    96301 agctatctgg agttttaaca tgccgcctcg ccgctataac cctgacaccc gacgtgacga
    96361 gctgctggaa cgcattaatc tcgatatccc cggcgcggtg gcccaggcgc tgcgggaaga
    96421 tttaggcgga acagtcgatg ccaacaatga tattacggca aaacttttac cggaaaattc
    96481 tcgctctcat gccacggtga tcacccgcga gaatggcgtc ttttgcggca aacgctgggt
    96541 tgaagaggtg tttattcaac tggcaggcga cgatgtcacc ataatctggc atgtggatga
    96601 cggcgatgtc atcaatgcca atcaatcctt gttcgaactt gaaggcccat cccgcgtgct
    96661 gttaacgggc gaacgcactg cgcttaattt tgtgcaaacc ctttcaggag ttgccagtaa
    96721 ggtacgccac tatgtcgaat tgctggaagg caccaacacg cagttgttgg atacgcgcaa
    96781 aaccttaccc ggcctgcgtt cagctctgaa atacgcggta ctttgcggcg gcggagcgaa
    96841 tcaccgtctg gggctttctg atgccttcct gatcaaagaa aaccatatta ttgcctccgg
    96901 ctcagtgcgc caggcggtcg aaaaagcgtc ctggctgcac ccggatgcgc cagtagaagt
    96961 cgaagtagag aatctggaag aacttgatga agccctgaaa gcaggagccg atatcatcat
    97021 gctggataac ttcgaaacag aacagatgcg cgaagccgtc aaacgcacca acggcaaggc
    97081 gctactggaa gtgtctggca acgtcactga caaaacactg cgtgaatttg ccgaaacggg
    97141 cgtggacttt atctccgtcg gtgcgctaac taaacacgta caagcactcg acctttcaat
    97201 gcgttttcgc taatagttga cagatttatc cgctccatcg cgggcggata atctcccctt
    97261 ccccaacttt cttcgtaacg cctcgcaaat ttcttgtctt tcgctgcaac gaaataaaaa
    97321 acctcggaat ctgctttccc gtttcgtttt ttgcccctcg cctgtgctga tggcgtttgc
    97381 caaagtagcg ccaaccaaat caaggagcga aacagatgga caagcaacgc ggttttacac
    97441 ttatcgaact gatggtggtt attggcatca ttgccatttt aagcgccatt ggtattcccg
    97501 cttatcaaaa ctacctgcgc aaagccgcac tcaccgacat gctacaaacc tttgtgcctt
    97561 accgtaccgc cgtagagttg tgcgcgctgg aacatggtgg attagatacc tgcgacggtg
    97621 gcagcaatgg cattccctcg cctaccacca cccactatgt ttcagccatg agtgtggcaa
    97681 aaggcgtggt gtcgctgacc gggcaagaaa gtctcaatgg actaagcgtc gtcatgacac
    97741 cgggttggga taacgcaaac ggcgtcaccg gctggacgcg caactgcaat attcaaagtg
    97801 acagcgcatt gcatcaagcc tgcgaagatg tcttccgctt tgatgacgcc aactaaggag
    97861 cggcaatgaa tattccacag ctcactgccc tgtgtctgcg ttatcatgga gtcttgctgg
    97921 atgccagcga agaggtggtt catgttgcgg tagtcgatgc accttcgcat gagctactgg
    97981 acgcattgca tttcgctacc accaaacgta ttgagatcac ctgctggacg cgccaacaaa
    98041 tggaaggtca cgccagtcgc acacaacaga cattgcccgt agctgttcag gagaagcatc
    98101 agcccaaagc agagttgcta actcgaacgt tacaatctgc gctggaacaa cgcgcgtctg
    98161 atattcatat cgaaccagcg gacaatgcct accgcatccg cttgcgtatc gacggcgtat
    98221 tgcatccttt accggatgtt tcaccggatg ccggagtcgc attaaccgcc agattaaaag
    98281 tgctgggaaa cctggatatt gcggaacatc gcctgccgca ggacgggcaa ttcactgtcg
    98341 aactggcagg aaacgccgtc tcatttcgta ttgcgacctt accatgtcgg ggtggtgaaa
    98401 aggtggtatt aaggttgtta cagcaggtga gccaggcact ggatgtcaac acgcttggaa
    98461 tgcagccgtt acaactggcg gactttgctc atgccttgca acaaccacag ggactggtgc
    98521 tggtaactgg ccctacaggc agcggcaaaa cggtcacgct ttatagtgcc ctgcaaacgc
    98581 tgaataccgc tgacattaat atttgtagcg tcgaagatcc ggttgagatc cccatagccg
    98641 gactaaacca gacgcaaatc catccgcgtg ccggactcac ctttcagggc gtgttgcgtg
    98701 cgttattgcg ccaggatcct gacgtcatca tgatcggaga gatccgcgat ggcgaaacag
    98761 cagagatcgc tattaaagcg gcgcaaactg gtcacctggt gttgtctacc ctacacacta
    98821 attccacctg cgaaacgctg gtacgtttac agcaaatggg ggtcgcccgc tggatgctat
    98881 catcggcgct tacgctggta atagcccagc gtctggtacg caaactttgc ccacattgtc
    98941 gccggcagca aggggagccc atccacattc cagacaatgt atggccatcg ccgctgcccc
    99001 actggcaggc acccggttgt gtacattgct accacggttt ttatggtcgt acggccttat
    99061 ttgaagttct gcccataacg ccggtcattc gtcagcttat ttccgctaat accgacgttg
    99121 aatcgctgga aacgcacgca cgacaggcgg gtatgcgtac gctttttgaa aacggctgcc
    99181 tggccgtgga gcaaggctta accacctttg aagagttaat ccgcgtactg gggatgccgc
    99241 atggcgagta agcaactctg gcgctggcat ggcataaccg gcgacggcaa tgcgcaagat
    99301 gggatgctat gggcagagag ccgtgctttg ctgctcatgg cactacagca acagatggtt
    99361 accccactta gcctgaagcg aatcgccatc aattctgcgc agtggcgagg agataaaagc
    99421 gcggaagtca ttcatcaact ggcgacgcta ctcaaagccg ggttaacgct ttctgaaggg
    99481 ctggcactgc tggcggaaca gcatcccagt aagcaatggc aagcgttgct gcaatcgctg
    99541 gcgcacgatc tcgaacaggg cattgctttt tccaatgcct tattaccctg gtcagaggta
    99601 tttccgccac tctatcaggc aatgatccgc acgggtgaac tgaccggtaa gctggatgaa
    99661 tgctgctttg aactggcgcg tcagcaaaaa gcccagcgtc agttgaccga caaagtgaaa
    99721 tcagcgttac gttatcccat catcatttta gcgatggcaa tcatggtggt tgtggcaatg
    99781 ctgcattttg ttctgccgga gtttgccgct atctataaga ccttcaacac cccactaccg
    99841 gcactaacgc aggggatcat gacgctggca gactttagtg gcgaatggag ctggctgctg
    99901 gtgttgttcg gctttctgct ggcgatagcc aataagttgc tgatgcgccg accgacctgg
    99961 cttatagtgc ggcagaaatt gctgttacgc atcccgatta tgggttcact gatgcgggga
   100021 caaaaactca cgcagatttt tacgattctg gcgctgacac aaagtgcagg cattactttt
   100081 ttgcagggcg tagagagcgt cagagaaaca atgcgctgcc cgtactgggt gcaacttctg
   100141 acacaaatcc agcacgatat cagtaacggt catcccatct ggctggcgct aaaaaatacc
   100201 ggggagttta gcccgctctg tttgcaatta gtgagaacag gagaggcatc cggctcgctg
   100261 gacctcatgt tagacaacct cgcccatcat catcgggata acacaatggc gctggcggat
   100321 aacctcgcag ccttactgga accggcgttg ctgatcataa cgggaggaat tatcggtacg
   100381 ctggtggtgg cgatgtatct gccaattttc catttaggcg atgcgatgag tgggatggga
   100441 taacgctggc gtgttgctcc acaccagcgt tggaagatta caggttgttg aagatgcggt
   100501 tttcttgttc ctgcacacgg ataaatgtgg tgcgcttggt cagttctttc aggcgtgaag
   100561 ccccaacgta tgtacaagct gaacgcaggc cgcccaaaat atcacgcgcg gtattttcaa
   100621 ccgggcctcg cagcggcagc ttaacggttt taccttctgc tgcgcgatat tccgcaacgc
   100681 cgccaacgtg acgtttcatc gcagactcgg agctcatgcc gtagaacagc ataaatttct
   100741 cgccgttctc ctcaacgatg cgaccgccgc tctcttcgtg gcccgccagc atgccgccaa
   100801 gcatgacgaa atcggcaccg ccgccaaagg cttttgcgac atcgcccggc gtggtgcagc
   100861 caccgtcgct gacgatcatt ccgcccagac cgtgcgccgc atcggcacat tcgattaccg
   100921 cagaaagctg cggataaccg acgcctgttt tgacgcgagt tgtacaaaca gaacctgggc
   100981 caatgccaac tttaacgata tcagcaccgg agaggataag ctcctcacac atttcaccag
   101041 tcactacgtt gccagcacaa atggttttgg tcggccacgc ttcacgcgct ttcgcaacga
   101101 actgcacgaa gtgttcggaa taaccattcg ccacatcaat acaaacgaag tttaatgccg
   101161 ggttcaggtc gagaatctgt ttagtttttt cgaaatccgc atcagacgta ccggtagaaa
   101221 ccatcacatg tttcagcaca tcagcggaag aattgttgat aaacgcttgc cactcttcga
   101281 cagaatagtg tttatgcaca gcagtcaaaa tatcaaaaga agccagcgca gaggccatag
   101341 aaaatgtacc tacggtgtcc atatttgcgg cgataattgg cacgccggac cagctctgac
   101401 ctgaatgttt gaaggtgaat tgacgttcca gttcaacatc ggaacggctt ttaagagtgg
   101461 agcgtttagg gcggatgaga acgtctttaa aacctaactt cagatcttct tcaatacgca
   101521 tgtgcggatt cctggggtta atggctataa gggtaagagc gcaactccag tgacgctatc
   101581 atacgcacta atcaatgcgg cgcaagactg cgaaattgtc tttttttacg ctacaatccc
   101641 ataaatttac ctggtaaata gtgagcgaac gtttcatcaa tttcgctttc gtgcactcat
   101701 ttttaacgtt ttgataatca tgatgaattc ccgggaatat aaattatgag gtatatagtt
   101761 gccttaacgg gaggcattgg cagtggcaag agtaccgttg ccaatgcgtt tgctgatctc
   101821 ggaattaacg tcattgatgc cgatattatt gcgcgtcagg tggttgaacc aggtgcacct
   101881 gcgctacatg ccattgctga tcactttggc gctaacatga ttgctgctga tggaacattg
   101941 cagcgccggg ccttgcgcga gcggatcttc gccaacccgg aagagaaaaa ctggcttaac
   102001 gccctgctgc atccgctgat tcagcaagag acgcaacacc agatccagca agctacttcc
   102061 ccctatgtac tgtgggttgt gccattgctg gtagaaaact cactgtataa aaaagcgaat
   102121 cgagtgctgg tggtggatgt cagcccagaa acgcaactta agcgcaccat gcagcgcgat
   102181 gatgtaactc gcgagcatgt cgaacaaatc cttgctgctc aggcaacgcg cgaagcccgc
   102241 cttgccgtgg cagatgacgt cattgataat aacggcgcac cggatgctat cgcatcggat
   102301 gttgcccgcc tgcacgcaca ctatttgcag cttgcgtcgc agtttgtctc acaggaaaaa
   102361 ccgtaatgca gacccaggtc ctttttgaac atccactaaa tgaaaaaatg cgtacatggc
   102421 tgcgcattga gtttttgatt cagcaactca ccgttaattt acccatcgtt gaccacgctg
   102481 gcgcgctgca tttcttccgt aatgtcagtg aattactgga tgttttcgag cgcggcgaag
   102541 tccgcactga gctgttgaaa gaacttgacc ggcagcaacg taaactccag acctggattg
   102601 gcgtgcctgg cgtggaccag agccgtattg aagcattaat tcagcagtta aaagcggcgg
   102661 ggagcgtatt aatttccgcg ccgcgtatcg ggcaatttct gcgtgaagat cgtttgattg
   102721 ctctggtgcg tcagcgactg agcatcccag gcggctgttg cagctttgat ttacctacat
   102781 tgcacatttg gctgcatcta ccccaggcgc agcgcgacag ccaggtagaa acctggattg
   102841 ccagcctgaa cccgctcacc caggcactta ccatggtgct ggatttaatt cgccagtcgg
   102901 ctcccttccg taaacaaacc agcctgaatg gtttttatca ggataacggt ggcgatgccg
   102961 acttgctgcg cctgaatctg tcgctcgatt cacagcttta tccgcaaatt tccggacata
   103021 agagccgttt tgccattcgt tttatgccgc tggacactga aaacggacag gtaccggaac
   103081 gtctggattt cgaactggcc tgttgctaag gagtgaaaat gtcagaaact attacggtga
   103141 attgcccaac ctgcgggaaa acggtggtgt ggggtgaaat cagcccgttt cggccatttt
   103201 gctccaaacg ttgtcagctg atcgacctcg gagaatgggc tgctgaagaa aaacgaatcc
   103261 ccagcagtgg cgatctttcc gaaagcgatg actggagcga agagccaaag cagtgacatt
   103321 tgtctgatgc cgcacgtagg cctgataaga cgcggacagc gtcgcatcag gcatcttgtg
   103381 caaatgtcgg atgcggcgtg aacgccttat ccgacctaca gacgcttaag cttcgcaatt
   103441 accggttcat tggctggcgg aaaatcatcg gcattaagac cgactagcga catccactca
   103501 ccgggttgcc cttctttacc ccacggctcc ccttcccagc tttcgaccag ccagaaccac
   103561 agagttatat gcctgtccgg gaattcatat tccagttttt caaatagcga aaaatgttgt
   103621 ggggtaatcc cgacttcttc ctgaagttca cgcaccaccg cctgttccgg cgtttcgccc
   103681 atttcaattt taccgccggg aaactccagt ttattcgcca tgtgcgcatc tgctgcgcga
   103741 cgcgttataa agatttcatt gttctcgttg cgaataatac ctaccgcaat ttgcagcttt
   103801 ttcattgtct taaacctata aaaaaggcgc agaatcctgc gccttttact tcaactgtta
   103861 gcttttattg caggcgacca tggcactgct tgtatttttt accagaaccg cacgggcaag
   103921 gatcgttacg tcctactttg cgctcaccgg tttgcgccgc cagtgcagct gcggctgcag
   103981 agtcgtcatc ctgatggcta agctgctgca tttgcgctaa acgctcggct tccatacgac
   104041 gctgttgttc cagctcctca acctcttcag gcatacgtac ctggactttg ctcagcgtgc
   104101 tgataacttc atattttaac gactccagca tcgctgcaaa catggagaac gattcacgtt
   104161 tgtattcctg cttcggatct ttctgtgcat agccacgcag gtggataccc tgacgcagat
   104221 agtccatcgc tgccaggtgc tctttccaca gggagtcaag cgtttgcagc atgacgcctt
   104281 tctcgaagtg acgcatcatc tcagcaccaa ccacttcttc tttacgctga tacacttcga
   104341 tggactgcgc cagaatgcgc tcacgcagcg tctcttcatg cagttctggt tctttatcca
   104401 gccactcggc aattggtaaa tcgaggtcga aatcgttctt cagacgttcc tgcagccccg
   104461 gaatatccca catttcttcc agcgactgtg gcggaatgta ggcatcaatg gtggctttga
   104521 acacatcttc acgaatgctg ttgatggttt cgctcacatc gctgacatcc agcagttcgt
   104581 tacgctggga gtaaatggcg cgacgctgat cgttagccac gtcatcatat tccagcagtt
   104641 gcttacgaat gtcgaagtta cgactttcaa ctttacgctg ggcgttggca atcgctttag
   104701 tcacccacgg gtgttcaatg gcttcgcctg gcttcatacc cagtttacgc atcatgccgg
   104761 atactcggtc ggaagcaaaa atacgcatca gcgcatcttc catcgacagg tagaaacggg
   104821 aagaaccagc atccccctga cgaccagaac gaccgcgcaa ctggttatcg atacgacggg
   104881 attcgtgacg ctcggtaccg atgatatgca ggccacctgc ttccagtacc gcatcgtgac
   104941 gtacctgcca gtcggcttta attttttcaa tttgctctac ggtcggattt tccagcgcgg
   105001 caacttctgc ctgccagcta ccaccgagca caatatctgt accacgaccc gccatattgg
   105061 tcgcgatagt caccgcagcc ggataacctg cctgagcaac aatcgccgct tcgttggcgt
   105121 ggaatttggc gttcaggacg ttgtgcttaa taccggcttt ggtcagttcg tttgacacca
   105181 gctccgattt ttcgatggag atagtaccca ccagcaccgg ctggcctttc gcagtacgtt
   105241 ctttgatatc ttcaatgatc gcctgaattt tttccgcttc agtcatgtag accaggtccg
   105301 gcagatcttt acgaatcatt ggacggttgg tcggaacaac gacggtatcc agcttgtaga
   105361 tggagctaaa ttcgaaagct tcggtatcag cagtaccggt catccccgcc agtttttcat
   105421 acagacggaa gtagttctgg aaggtgatcg aagccagcgt ttggttttcg ttctggatct
   105481 gcacaccttc tttcgcttcc acagcctggt gcagaccatc ggaccagcga cggccctgca
   105541 tggtacgacc ggtgtgttcg tcaacgatga taacttcacc atctttaacg atgtagtcga
   105601 cgtcgcgggt aaacagcgca tgagcgcgca gcgccgccgt tacgtggtgc atcagcatga
   105661 tgttggccgg agagtacaga gactcccctt catccatgat gccctctttc accagcagtt
   105721 cttcaatcag caccagacca cgttcggtca ggttcacctg gcgagatttt tcgtccaccg
   105781 agaagtggcc ttcgccctgg aaggtttcgg agtcttcttt ttcctgacgg atcaggtgcg
   105841 gaataatttt attcacgcgt ttatacattt ccgagctgtc ttctgccggg ccggaaatga
   105901 tcagcggtgt acgcgcttca tcgatcagga tggagtccac ttcgtccacc agcgcatagt
   105961 gcagtttacg ctgtacacgt tcttcagggc tgaacgccat attgtcgcgc aggtagtcaa
   106021 agccgtattc gttgttcgta ccgtaagtga tgtcagctgc gtaagcttcg cgctttgccg
   106081 gtgctggcat gcccggcagg ttgataccga cagtcaggcc aaggaattca aacagcggac
   106141 ggttgttttc ggcgtcacgt tgcgccaggt agtcgttgac ggtaactacg tgcacgcctt
   106201 taccggttag tgcgttcagg taagcaggca gcgttgcggt cagggtttta ccttcaccgg
   106261 tacgcatttc ggcgatgcag cgttcgttaa gaaccatacc gccgagtaac tgaacgtcga
   106321 agtgacgcat accaaagacg cgcttacttg cctcacgtac cacggcgaaa gcttccggga
   106381 tcagattttc cagcacttcg cctttttcca gacgtgcacg aaactctgcg gttttccctt
   106441 tcagttcttc gtcggagagt ttttccatct ccggttccat ggcattgatg atgttgacca
   106501 ctttgcgcat ccggcgcagg gtgcgatcgt tacgactacc gaaaacttta gttaacaatt
   106561 tgattagcat aataaaatct caaacgcccc gcgttgcgga gttaataaaa tgaagtaaag
   106621 gtttattgtt gttaggtgag gcgttgaggg ccagcacgga tgccttgcgc ctggcttatc
   106681 cagacgggcg tgctgaattt tgcttgtggg gtaaaatgcg cataatcaat gcgataaccc
   106741 ttttcagacg gcgtgccttc ctgggtcagc agcgcgctga gcgtatccag taatgcaaga
   106801 tgttgcgcct gaagaggcaa agattcttca gcaacgggca gtgtttgcgg tgccattgcg
   106861 aaagaaagat gacggattac cgtgcgaatg gcatgttgat gccagtaatc aacggaatag
   106921 ttcgaattcg ggcggcgtgt gttcgcttcc agcaaggcca attgaccaaa gttaactttg
   106981 gctgaaggct cgtggttgcg ggttgtcgct tttgcgggcg cgtttggttc ggcggcgttg
   107041 ctgagcgcag gcaaacctaa actcgccgca accatcccta ataagagatg cggccagaag
   107101 tagcgtttac caaactgtcg ccagcgcgtc agtattccac tcacgttatt gccatcccga
   107161 tcgtattcaa acgtatttag cgcacaaatc ttatcattaa agcctgcagt ccacagcacg
   107221 aatgaagata agttgtgcgg aaaagtgctt aagaaaacag cgttcgcacc gttttttata
   107281 gctcttataa aatttaaaaa aaaacgactg gttcacctgg ccggagagag tgccagattt
   107341 gccagtcgaa ttttatacga cagtataaat gtcgttatgc cagtacagct gaaggcgctt
   107401 tgaaggccaa cggcagttct gcgtcgtcct ggaaggtcac atattcccag gcttcctgtt
   107461 tcgccaggac agcctgcagc agtttgttat tcagtgcatg accggattta taagcggtaa
   107521 atgcaccaat aatattgtga ccacacatga acaagtcacc gatcgcatcg agcattttgt
   107581 gacgcacaaa ttcgtcttca aaacgcaggc cgtcttcgtt cagtacgcga taatcgtcaa
   107641 caacgatggc acaatcgaag ctgccgccca ggcacaaacc acgggactgc agatattcga
   107701 tatcacgcat gaaaccgaac gtacgcgcac ggctgatctg gcgcataaac gcatcagcgg
   107761 agaagttcat cgcatagcgc tggttgctgg aatcaatagc cggatggtta aaatcgatgg
   107821 tgaaatccag cgaaaaacca ttgtacggct taaattcagc ccacttatcg ccatcttcga
   107881 cacgaacagt ctctttgatg cgaacaaatt ttttggcgca gttcaactcg tcgataccgg
   107941 cgtcaagcag caggtataca aacggagcgg cgctgccgtc catgatcggg atttccggcg
   108001 cgttaacttc gataacaatg ttatcgatgc ccaagcccgc gagagcagca ttgaggtgct
   108061 ctacggttga aatccgtaca tcatgctcgt tgaccagaca cgtacagagc atggtatcac
   108121 gcacagattt ggcatcggcc gggaaatcta ccggtggatt caagtcggtg cgacgataga
   108181 tgaccccggt gttggccggc gcagggcgta acgtcagggt gactttcttg ccggtatgta
   108241 aaccgacacc cgtcgcctga acgatacgtt taagtgtcct ttgtttgatc atcgtattat
   108301 ctcgccaaat tacctatcca actgaagtgt actatacatt cggcgggcca gtttagcaca
   108361 aagagcctcg aaacccaaat tccagtcaat tcttaatcag cttgcttacg caggaatgct
   108421 gggatatcca gataatccgg ctctttcgca gtttgcggcg cattgtcatt cacgacttta
   108481 gcaaccggct tctgctcctg ggtcagcgga gccatcccat gctgctggta gcgatccatc
   108541 actggctgct gaacctgctt attggtcacc agagtgattt caggacgttt gtccatgccg
   108601 atacctgtcg caacaacggt tacgcgcagc tcgtcattca tatccgggtc aagagaagta
   108661 ccgataacca cagtcgcgtt gtcggaagca aatgcacgga tggtgttacc taccgtttcg
   108721 aactcatcca gacgcaggtc gaagcccgcc gtgatgttaa ccagcacgcc gcgcgcgcca
   108781 gacaggtcga tatcttccag cagcggagaa gagatagcca tttcagcagc ttcttccgca
   108841 cggtcttcac cgctcgccac gccagaaccc atcattgcgt agcccatctc agacattacg
   108901 gtgcgtacgt ctgcaaagtc cacgttcatc aaacccggac gagtaatcag ttcagcgata
   108961 ccttgcacag cgcctttcag tacatcgttc gctgcgccaa acgcatccag cagggagata
   109021 ccgcggccca gaactttcag cagtttgtcg ttcgggatag tgatcagaga gtccacatgc
   109081 ttggacagtt cagtgatccc ctgctccgcg aatgccatac gcttcttgcc ttcaaagttg
   109141 aaaggcttag tgacgacagc aacggtcagg atacccaaat cttttgccac ttcagcgacg
   109201 actggtgctg cacctgtacc ggtaccaccc cccatacccg cagcaataaa gaccatgtct
   109261 gcaccttcca gcgccgcacg caatgcatcg cgatcctcat cagccgcatt gcggccaact
   109321 tctggattag cgccagcgcc cagtcctttg gtgataccgc taccgatttg aatcgtctgt
   109381 ccaaccgctg ttttacgcag cgcttgtgca tcggtattta ccgcgaagaa ttcaacacct
   109441 tcaatgcgct cgcgcaccat gtgttcaaca gcattaccgc cgccgccgcc gacgccgatg
   109501 actttaatca ccgcgtcatt ggtaagttcc attggttcaa acatagtttc tctccgattt
   109561 gtgcctgtcg cctgaggccg taatcatcgt cggcctcata aaaattaaaa ctcttttcgc
   109621 agccaactat tgagtcgctt gatccacgag ccaactgatg ctgtaacacg tttttctact
   109681 tcagcttcac cgttaagatg tgactctttc ccatagtgaa gcaatcccac cgccgtcgaa
   109741 taatacggct cctgagcata atccgttaaa ccggtaatgt tcagcggcgc gccgatacgc
   109801 acttgcgtat gaaacacgcg ctgagcacag gctgcaagac cttcgatctg cgctgcgcca
   109861 ccggttaata caatgcctgc cgccaggtga tgtttaaccc cttgttggcg aagcttttcc
   109921 tgcaactgca atatctcttc gttgaccagg ttgagcagct cggtatagcg cggctcgatc
   109981 acctctgcca gggtctgacg ttgcagactc cgcggcggac gaccacctac gctcggcact
   110041 tccacgctct catcttttcc aacgatggaa cccagcgcac aaccgtggcg aactttaatc
   110101 gcttcggcgt cgcttggcgg cgtgccaaag gcgtaagcga tatcactggt cacgacattg
   110161 ccagcataag gaattacctt agtgtggcgc aatgccccac cggtataaac ggcgatatcc
   110221 attgtaccac caccgatatc gacgacgcag acacccagtt cacgttcatc ttccgtcaat
   110281 accgaataac ttgatgccag tccggcaaat atcagttggt caactttcag cccacaacgt
   110341 tcaaccgctt tgacgatgtt tttcgccata tcgttgtgac atgtgatcag gtgcactttt
   110401 gcctgcatcc gcacgcccga aagtcctacc ggattcttga tcccttcctg atagtcaatc
   110461 gcatactctt gcgggatcac atgcagcaca cgatgctcat cgcgcacacg caccgatttc
   110521 gcggtatgga cgacgttttc cacatcttct tgcgtcactt cttcttcaga aataggcacc
   110581 ataccaattt cattctggca gctgatgtgc ttaccagaaa gcgccagata taccgaagag
   110641 atctgacaat ctgccatcaa ttctgcctgg tcaatggcgc gttgtacgca cttgaccacg
   110701 gattcgaggt cgttcacccc gcctttatcc ataccacgtg acgggcagct tcccacgcca
   110761 atgatattga ccataccgtc gggcagaact tcccctacta aagcggcaac cttcgcggta
   110821 ccaatctcca gtcctactac cagttttctg tccgtcgcct tgatcattgt tgttctgcct
   110881 gtgcctgatt ttgttgctga gtagattcct ctggcggcaa gggcgcccag cctactgccg
   110941 ctccagagtc ataacgcaaa tcaacgtagc taatccgttt gccatcggtt tgcgcctgct
   111001 gctgtaaaac cggataaagt tctacaaagc gagccaaacg tttcatcgta tcgccccggc
   111061 caagattgag cttaatatcg ttattcagcg tcaactgcca ggaacgccgc gcggtcatcg
   111121 ccgcttcctt cagagtaaat ctgtcctttg ccagcatctg ccccatttcg cgatagccct
   111181 gcaacacttc attggcgctg ccttccgggc catacagcat tggaagcacc tgcttgctgg
   111241 tgcgatctgg cggcacgctg aaggtgtttc cttccgcgtc taccatatgt tgatcattcc
   111301 accgcgcaat cggcacatat tcaaccagat gaatcttcaa ttcatcaggc cactgctttc
   111361 tgacgctcac ctgcttaatc cacggcaggc gttgttctat ttgcgtctgg atgatgttga
   111421 catcttgggt cataaaggta cccggctcac ccaatgccag gatcgactgc cggatatcgt
   111481 cattacgcgt gtaatggcgt tcaccggtca acaccagctt tgagagcggc aggcgttgcg
   111541 catcttccat ccagcccaac acgacccagc cgctcaccaa cactgtcgtt aaaacggtca
   111601 gcaggaaaag gatccccgcc agacgcgttc cattattgcg gcgagaagaa acctcttctt
   111661 cgctatttcg cgtgttcaga gcagcctgcg acatattagt ccgccagttc cagaattcgt
   111721 actaccaact gcgagaagct catacctgcc tgacgtgccg ccatcggcac caggctgtgg
   111781 ctggtcatac ccggtgaggt attggcttcc agcagataaa actgtccatc gctgtccagc
   111841 ataacgtcaa tacgtcccca tcctttgcaa cctaacgtcg tccatgcttt cagcactaat
   111901 gcctgcaaat tggcctcttg tgacgcttcc agacctgcgg ggcagaaata ctgtgtctca
   111961 tcagagagat acttcgcctc ataatcatag aaggttccgg acggttgaat acgtattgac
   112021 ggtaaaattt cttcaccgag tatcgcaacc gtgaactccg gcccacttag ccatttttca
   112081 atcaatactt cttcatcgtg ctgaaatgcc aatcttaatg catcttgtag agcattttct
   112141 gctactactt ttgacattcc cacactggaa ccttcgcggc tcggcttaac gataaccggc
   112201 aaacccagag cagaaatttc tgctaactgc ttatcgctca ggcctttttc aaactctgcg
   112261 cgggttaacg ctacccacgg cgcgaccggt aaaccggcac cttgccacag cagtttgctg
   112321 cgtagtttat ccattgaaag cgcagatgcc atcactccgc tgccggtata aggcaagccc
   112381 atcagctcga gcatgccctg cagcgtacca tcttcaccgc cgcgaccgtg tagcgcgata
   112441 aacactttct gaaaacccat cgacttcagt tgcgtcacgt cgacttcttt cgggtcgaca
   112501 ggatacgcat caataccgcc ttcacgcagc ccggctaaca ccgctgcgcc agaattcaga
   112561 gaaacttccc gctcagcgga agtcccgccc aacaggaccg cgattttatc agtcatgttg
   112621 ttcttcctcc ggagtttgcg gcttcagttt gatttcagct aaagaacggg caatttttcc
   112681 gatattacca gccccctgaa cgagaatcag gtcgttaccg gttaataccg gtgccagcat
   112741 ctcggctacc tgcgcagggt ccggcaccag aatgggatca attttcccac gtccacgaat
   112801 tgtgcgacac agcgaacggc tgtccgctcc cggaattggc gcttcgccag ccggatacac
   112861 ttccagcatc aacagggtat caacctgcgt cagcacattg gcgaaatcat catacaggtc
   112921 gcgcgtacgg gtaaaacggt gcggctgaaa cagcattacc aggtttttat ccggccagcc
   112981 tgcgcgcgcc gctttaatgg tggcgtcaac ttccgtcggg tggtggccgt agtcatcgac
   113041 cagcattgcc gtaccgcttt taccattcac tggctccagc gggaattcac cgaggaaatc
   113101 aaaacggcgc ccagtcccct ggaagctctc cagcgcacgt aaaatagcct cgtcatcaat
   113161 tccctcttcc gtagcaaccg caaccgcagc tgcggcgttc agcgcgttat gacgacctgg
   113221 cgcattcagg gtgacgcgca tcggctcttt gtcctggcgc agcagcgtaa agtgcccctg
   113281 cgggccaatc tgctgataat cttctacacg cacgtcggca tcttcgctga agccgtaagt
   113341 cgtggtctga cgtcccactc gcggtaacaa ttcgcggatc accggatcat caacacacat
   113401 caccgcacga ccgtaaaacg gcaggttgtg cagaaaatta ataaaagtct gttttaaatt
   113461 ctcaaagtcg ccctggtagg tatccatgtg gtcggcttcg atattggtga caatcgccac
   113521 catcggttgc agatgcagga acgatgcatc actctcatct gcttcggcaa tcaggtaccg
   113581 accatgcccc aaacgcgcat gaacccccgc cgcttttacc agcccgccgt taacgaaggt
   113641 tgggtcgagc cccgcttctg cgtagatgct ggaaaccatc gcggtggttg tcgttttgcc
   113701 gtgcgttcct gcaatggcga tgccatgacg aaaacgcatt aactcagcca gcatttcggc
   113761 acgacggatc accggaatac gcgcttcatg agctgcgaca atttccgggt tatcggcaga
   113821 aatggcgctg gaaacaacga ccacgctggc atcacgtacg ttttccgggc gatggttgaa
   113881 ataaatcgtc gctcccagat tcattaactg ctgcgtgacc ggatttggcg ctaaatcgga
   113941 accactgatc tgataacctt cattggccag aacttcggca ataccgccca taccggcacc
   114001 accgatgccg acaaaatgta tgtgccgaac gcgacgcatt tcgggcacga tggaacgcag
   114061 ttttgccaat tgttgtgtat tcattcttta cgccattaac ttcttaaatt catacgatgc
   114121 aaaaggcatc gctacaatta cgcccgggca gcccggctca cttcatttgc cactcgctcg
   114181 gtggcatccg gaatggatgc agcgcgggcg cgttctgcca tggttaataa ggtttctcgc
   114241 gaccacccgg ccagggtgtt ggcgacagca tccacgctaa gctgtggctg ctcgataatt
   114301 ttggctgcgc ccgctttttc cagcggtagc gcattccagt attgctggcg gtctttatgt
   114361 tgaaacggca caaacaacgc cggtagtcct gccgcggcga tttcactcac cgttaaagca
   114421 ccggagcggc aaacgacgac atccgcccac gcatacgccg ccgccatatc atcaataaat
   114481 tccgtcactt tatgctgcgg ttgccccgct tcggcatacg cctgttcaac ggattgttgc
   114541 gaacctttac cgctctgatg ccagatagtg actgaatcac ccagtttcgc agcaacctgc
   114601 ggcattgtct ggttaagaat gcgtgcgccc tgggaaccac ccactaccag cacacgaacc
   114661 ggaccttcac gtccagccaa acgttgctgc ggcaacggca gcgccagtac atcggtacgc
   114721 accgggttac ccaccacttc cgcattaggg aaagcgcctg gaaacgcctg catcactttg
   114781 gtggcaatct tcgccagcca tttattggtt aagcccgcaa taccgttttg ttcatgaagt
   114841 acaaccggaa tgcctaacga ccacgcggcc agaccacctg gacctgatac atagccgccc
   114901 ataccgagta ccacgtcagg tttgtacgct ttcataatcg cccgcgcctg acgccaggcg
   114961 ttgaagatac gcagcggcgc agctatcagt gcttttatac cttttccacg cagaccagag
   115021 atacgaatga aatcaatttc gatgccatgt tttggcacta agtccgcttc catacggtcg
   115081 gcagtcccca gccagcgaac ttgccaaccc tgagccatta gatggtgcgc aaccgccagt
   115141 cccgggaata catgtccacc ggttccgcct gccatcacca ttaatcgctt tccttgacca
   115201 ctcatcgtga acctcgtaca aacgcctgcg ctttctccag acgcgtttca taatcaatac
   115261 gcaacagcat catgatggct gtcgacataa tcagtaagct cgaaccaccg taactgatca
   115321 gcggcaatgt cagacctttg gtcggtaaca tccccgccgc cgcgcctacg ttaaccagcg
   115381 cctggaagct aaaccagatg ccaatagaac aggcgagaaa accggaaaaa cggtggtcaa
   115441 tttctaacgc tttgcggcca atcgacatcg cgcgaaaagc gacgaagaat accattaaaa
   115501 gtgccagcac cacaccgaca taccccagtt cttcgccgat aatggcgaaa ataaagtcag
   115561 tgtgcgcttc cggcagatac tccagttttt gtaccgagtt acctaaacct tgtccccaaa
   115621 gttcgccgcg accaaacgcc atcagcgatt gcgttaactg atagccgctg ccaaagggat
   115681 cttcccacgg gttccagaat gcggtaacac ggcggatacg gtacggttcg gcgagtatca
   115741 gcaacacaac cgctgaaatg cccataccga taatggcaat gaactgccac aatttcgctc
   115801 ccgccaggaa caacatcgcc agcgtagtca caaacaacac caccaccgta ccaaggtctg
   115861 gctgtgccag cagtaacact gccaacacca gaatcacgcc catcggtttc aggaagccgc
   115921 gcaggttatt acgtacttcg tcgcctttac gcaccagata gttggcgata taacaaaaca
   115981 gcgacagttt tgtcagctcc gcaggctgga tacgcagcaa accgagatcg atccaacgcg
   116041 atgccccttt aaccgagcta cccactacca gcacgatcat cagcaggatg atagatccga
   116101 gcagcatcgt ggcactgtag cgttgccaga actccatcgg cagacgcagc gtaatgatcg
   116161 ccagaatgaa tgccaggatc agatagacgc catcacgctt cgcgaagaag aacggatcgt
   116221 tggttaagcg ttgccctatg ggcattgacg ccgaggtcac catgataaag ccaatcgccg
   116281 caaggccgaa ggtcagccac agtaaggtgc gatcgtacat gatcaggctg tcggtatctt
   116341 tttcccgcga gcccatcacc cagcctttta gcgccgtgga gatccagacc aggatactga
   116401 atcctggcag gcgcggcatt ttcaggcgag ggagagataa acgcatcaac ctaactcctt
   116461 cgccagacgg gcaaactcat tgcctcgttg ttcaaagttc ttgaactgat caaggctggc
   116521 acaggccggg gagagcagaa ccatatcgcc cggctgaaca cgcggagcca gcaagcgcat
   116581 cgcctgttcc atagtttcgg tttgttctgc cacttccggg cgtagcgccg ccagctgcgc
   116641 accgtcacga ccaaaacagt acaaacgcac gttgtcgcca ttcagatagc gcgccagtgg
   116701 actgaagtcc gccgatttac catcgccgcc cagcaacaaa tgcagcgtgc cgtctacctg
   116761 caagccattc aacgccgctt ccgtactgcc gacgttagtg gctttcgaat cgttaatcca
   116821 gcgtacgcca ttgtgctcca gcaccacttc aaagcgatgc ggcagaccgg tgaaggtggt
   116881 taacgctttc aggctgctgg cgcgcggcaa accagctgcg tctgccagtg ccagtgctgc
   116941 cagcgcattg gtgtagttat gctgcccgga aagtttcatc tctttcacgt tcagcacttt
   117001 ctcgcctttc actcgcagcc aggtttctcc ctgctgatga ttcaggtgat agtcacccat
   117061 gttgacgcca aagctgacgc agcgttcatc agcaccgcga atcggcattg ttaaggcatc
   117121 atcagcattg acgacacaaa ctttcgcatt ttcgtaaata cgcaattttg ccgcacggta
   117181 ttgctgcaaa ccaaacggat agcggtccat atgatcttca gtcacgttca gaatggtcgc
   117241 cgccaccgcc tgtaagctgg aagtggtttc cagctggaag ctcgacagtt ccagcacgta
   117301 cagttcgcac tcagcatcaa gcagcatcaa cgctggcagg ccaatattgc cacccacacc
   117361 aacgttaacc cccgccgctt tcgccatttc acccactagc gtggtgaccg tgcttttgcc
   117421 gttagaaccg gtaatcgcca caatcggtgc ttgtgcttcg cggcagaaca gctcgatatc
   117481 gccaacgatt tcgattccgg catcagcggc agcgcttaag gatggatgcg ccagtgcaat
   117541 accgggactg gcgacaatca gatctgccgc catcagccat tcatcattca gactgcccgt
   117601 gtggcgttct acggcttcgg gtaatttatc caggccaggc ggtgtcatac gcgtatccat
   117661 aacgcgcggc gtcacaccgc gagcgaggaa aaagtccacg caggaaagcc cagtgaggcc
   117721 caggccgata atgacgacat ttttaccctg ataatcagcc atgattaacg taccttcagc
   117781 gttgccagac caatcagaac cagcatcagc gaaataatcc agaaacgcac aatgacgcgc
   117841 ggttccggcc agcctttcag ttcatagtgg tgatgaatcg gtgccatgcg gaaaatacgt
   117901 tgtccgcgca gtttaaagga gccgacctgc aggatgacag aaagcgtttc taccacgaac
   117961 acgcccccca taatcaccag caggaattcc tgacgtagca gtacggcgat aatgcctaac
   118021 gcaccaccta acgccagcga acctacatcg cccataaaga cctgcgccgg ataggtgtta
   118081 aaccacagga agcccagtcc tgccccgact atcgccgtgc agacaatgac cagttccccg
   118141 gcgtgtcgca gatacggtat gtgtaaatag ctggcaaagt tcatgttgcc ggtcgcccac
   118201 gccaccagcg caaaaccacc ggcgacaaat acggtcggca taattgccag gccgtcgaga
   118261 ccatcggtca ggtttaccgc gttgccagta cccacaatga cgaagtaagc cagcagaatg
   118321 tagaacaacc ccagctgcgg catcacatct ttaaagaatg ggaccaccag ctgcgttgcg
   118381 ggcgtgtctt tgccggcaag gtacagggcg aaggcgatac ccagcgcaat gaccgacatc
   118441 cagaaatact tccaacgagc gatcaaccct ttggtgtctt tacgcaccac tttgcgataa
   118501 tcatcaacaa agccaataac accgtaacct accagcacca ccaacacgca ccagacgtac
   118561 ggattggacg ggtaagccca cagcagtacg gagatcacaa tcgccgtcag gatcataatc
   118621 ccgcccatgg tcggcgtacc gcgcttgctg aagtgtgatt caggaccgtc gttacgcacc
   118681 acctgaccaa aggaaagttt ttgcaaatga gcaatcatac gcgggcccat ccacaatgag
   118741 atgaacagcg cggtcagcag gctgacgatg gcgcgaaacg tcagatagga aaagacgtta
   118801 aagccggaat aatatttgac caaatgttcg gccagccaaa ctaacatgtc ccattctcct
   118861 gtaaagcgcg tactacctct tccatggcgg cactacgtga acccttaact aaaatcgtaa
   118921 ttacctgttg ctcagcaatc agtgatttaa gacgcgtaat taacgcagtt ttatcagcaa
   118981 aatgttcgcc aacgccgctg gcggtgctga tagcatggct ttgtttaccc acgcttaaca
   119041 cgcggtcaat accagcagct tttgccgcct cgcccacctg tacatggcag gcttcgcttt
   119101 cagcgcccag ttccgccata tcgcccacca ccagcacgcg gtagcccggc atttcagcca
   119161 gtacctgaac agcggcggtc attgaaccga cattggcgtt gtaggagtcg tcgagcagca
   119221 actggttttc tgccagttgg atggggaaca gacggcctgg aacagctttc agatttgcca
   119281 gccccgcttt gatagcatca agcgttgcgc ccacggacat ggagagcgca gcggctgcca
   119341 gcgcattcgc aatattgtga cgccccggca acggcagcag aacatcgacg ctaccggttg
   119401 gggtttgtag ggtaaattcc gtaccgtgcg aggtcacatg gatattggtg gcggtgaaat
   119461 cgctgttggc ggcattgggt gagaaacgcc acactttgcg tgagccaatt acgctctgcc
   119521 agttcagcca gtcgttgttg tcggcgttca taatggcgat accgttttcc ggcaggccgc
   119581 taaagatttc acctttcgct ttcgcgacac ccgcaagcga gccaaaacct tccagatgcg
   119641 ccgctgccag gttgttgacc agcgcagctt ccgggcgagt cagactcaca gtccaggcta
   119701 tttcgccctg atggttcgcg ccaagttcaa taactgcgta atcgtattcc ggcgttaagc
   119761 gcaacagcgt catcggtaca ccgatgtcgt tgttgagatt gcctgccgta taaagcgtgt
   119821 tgccgcactg gcttaaaatc gccgccgtca tctctttaac ggaggttttg ccggaggacc
   119881 ccgtcagagc aaccacgcgc gccggaactt gctggcgaac ccatgcagcc agttcaccaa
   119941 acgccagacg cgtatccttg acgattaact gcggcaggtc gatgtccagc ggacggctaa
   120001 ccagtagtgc gcctgcgccg ccagctttcg cctggtcggc aaaatcgtgg gcatcaaaac
   120061 gttcgccttt cagggcaaca aacaggcagc ccggcgtcag ttttcgggta tcagtggtta
   120121 cagcatcaag ggtgatatct gcaccttgca gttcaccgtt gagaatatcg gtaagttggc
   120181 taagggttac gctaatcatg caatcacccc cagcagacgc gccaccgtga cgcgatcgga
   120241 gtagtccaga cgctgattgc caacaatctg gtaatcctca tggcctttgc ccgcgaccag
   120301 taccacatca ttctctttag cctgcataac ggcgcaagtc accgcttcag cacggccttc
   120361 catcactttg gcatgtccgg catctaacat tcccgccaga atatcgttga tgatggcacg
   120421 cggttcttcg gtacgcgggt tatcgtccgt caccaccgcc acgtcagcaa actcttcggc
   120481 aattgcgccc atcagtggac gcttaccttt atcgcgatcg ccaccacagc caaagacgca
   120541 ccacagcttg cccgcacagt gcaggcgcgc cgcctgtaag gctttttcca gtgcatccgg
   120601 cgtatgcgcg taatccacca ccaccgtcgg tttgcctggc gcagtgaaca cttccatacg
   120661 tccgcaaacc ggttgcagac gcgcggcggt ttttaacaga tcagccagcg ggtagccaag
   120721 tgccagcagt gtcgccagcg cgagcagcag gttgctgacg ttaaaagcgc ccatcagatg
   120781 gctttcaatt tcgccatcgc cccaacttga actaaagcga atggtcgcgc cgctgtcgtg
   120841 atagttcact tcggtcgctt tcaaccagcg tccgtgacag ttcggattga tatgatcttc
   120901 cattgatacc gcaaccgcgt ccggcagttt tgccagccag cggcggccca cttcatcgtc
   120961 ggcgttaaca atcgcctgac cacaatgatg ttcagaataa agcagccatt tcgcggcttc
   121021 gtagtgttcc atatcaccat gataatcaag gtgatcgcgg cttaagttgg taaagaccga
   121081 cgccgcaaat ttcaatgccg ccacacggtg ctgtaccagc ccgtgggagg aaacttccat
   121141 tgcgcaaaac gtcgcgccct gatccaccag ccccgccagc tcatgctgaa catcgactgc
   121201 cgaaccggtg gtattttctg tcgggatcac tttccccagc agaccgttac caacggtgcc
   121261 cattaccgcg ctggtttcgc caagcagttg gctccactgc gccagcagct gggtagtcgt
   121321 ggttttgccg ttggtgcccg ttacgcctac gagacgtaaa ttgtcagagg gttcatggta
   121381 aaagcggccc gccagtgcag ataaacgctc gttgagctgg ctgagataga tgaccggtac
   121441 gccgtgcatt tcacggattt caccgtcggt cgcctcacct ttcgcctctg caataatggc
   121501 agccacacct tgcgctatcg cctgcgggat atatcgacgc ccgtccgcct gatgacctac
   121561 tacagctaca aagagatcgc ccgccgcagc cacacggctg tcgagtgtca tctctcgcag
   121621 tgctcgcgaa ggtgcgtctg gcacccacgg agcaagaagg tcgcgcaaat tacgatctgc
   121681 cacctgtccc ctcgccttga ttaatcacaa attcattttt atcgcccgtt gtcagcgcat
   121741 ccggctcgat gttcatggta cgcaatacgc cgcccatgat ggcaccaaag accggcgctg
   121801 aaacggcgcc gccgtagtat ttacccgcct gcggatcgtt gataacaaca accagcgcga
   121861 agcgcggctg actcgcaggc gcaacgcctg cggtataagc aatatattta ttgatgtagc
   121921 gaccgtccgg cccgaccttt ttcgcggtac cggttttaat ggcgatacga tagcctttaa
   121981 tcgccgcctt cacgccgccg ccgcctggta gcgccacgct ttccatcata tgcaccacag
   122041 tgcggacaat ggattccggg aagacacgtt caccgggaac cggggggtca actttggtaa
   122101 tcgacagtgg gcgataaatg ccgtagctgc cgatagttgc gtagactcgc gctaactgta
   122161 acggtgttac cattagcccg tagccgaaag agaaggtggc cctctctatg tcagaccacc
   122221 gttgtttttg aggatataag ccactgcgtt ctccgaccaa ccccaaattg gtcgcttttc
   122281 ccagtccaaa acgtgagtaa gtatctacta acgctgagga cggcatcgct aacgccagct
   122341 tggaaacacc gacgttactc gacttctgta ataccccggt cagggttaat tcgctgtagc
   122401 gtgccacgtc tttgatttcg tggccgttaa ttcgataagg aatggtattg agtaccgagt
   122461 tttcccgcac cacgccacgt tgcaacgcgg tcattaccac catcggttta accgttgagc
   122521 ccggttcaaa cacgtcggtg atggtacggt tacgcatcgc ctctttcggc gtgccgctca
   122581 gattgttagg gttgtatgac gggctgttag ccatcgccag cacttcaccg gtgttgacat
   122641 ccaccagcac ggcgctacca gattcagcct tgttaaaggc caccgcgttg ttcagttcgc
   122701 gataaaccag cgcctgcagg cgttcatcaa tactcagcgc caggttgtgc gctgcctggc
   122761 tgtcagtaga agaaatatct tcaattacgc gaccatagcg gtctttacgc acaatgcgct
   122821 cacccggctg cccggtaagc catttatcga aactcttctc aacgccctca atcccttgac
   122881 tatcgacgtt agtaaagccg atgaggtgag cagtcacttc gccggacgga tagtaacggc
   122941 gagactcttc acgcagatga atccccggca gtttcagttt tttgatgtag tccgccatgt
   123001 cagggttcac ctgacgcgcc agataaataa agcgcccttt cgggttggcg ttaatgcggg
   123061 ctgaaagctg atccagcgga atattgagcg cgttagccag cgccttccag cggtcaccga
   123121 cgctgatacc gccagcgtca tgcacttctt tcgggtcagc ccaaatcgct tttaccggca
   123181 cgctcaccgc taacgggcga ccagaacggt cagtaatcat gccgcgggag gtggaaactt
   123241 gctgaacgcg aagagaacgc atgtcgccct ctttcaccag catatccggg gagataactt
   123301 gtaaccacgc tacgcgtccg agcagaaaag ccagcgccag gagaatacag ccgcataaca
   123361 acgcaaaacg ccaactgata aagttggcat gttcttcctg acgttttggt ttctgcgttt
   123421 tcgccgctgc tttcatgcgt cgcgtttatc cttatttttg cactacgata ttttcttgtg
   123481 acggatcaac atgctgcatt tgcagctttt ccgtggcgat cctttccacc cggctatggt
   123541 cgccgagcgc attctcttca aggatcaggt tgcgccattc aatatctaaa gcatctcgct
   123601 ccagcaccag ttgttcgcgc tgagcggtca gtaaacgggt atggtgcgcc gtggttacca
   123661 cagtcaccgc cgtcaaaata atgcaaatga acaggcagag tggcagcttc ccaaatcgca
   123721 aaagatcgtc accgataaca ccaggcaatg catggcgctc gtggcttccc atcgatcctt
   123781 taactttgct tagagcttct gtcactctgc tgatcatgca ttcgtcctct ctgcaatacg
   123841 cagaactgaa ctacgggcac gagggttctc agccacctct tcttcgcccg gcattaactt
   123901 gcctagtgct cgcagctgac ggccacccag ttttttgagc tgctcttcag tcatcggtaa
   123961 ccctgccgga acttgcggac cgcggctgtt ttcacgcata aaacgtttca caatacggtc
   124021 ttccagcgag tggaagctga tgatcgaaag ccgcccaccc ggggccagca cgttgagcga
   124081 gctttttagc gcctgctcta tctcctccag ttcactgttt acccaaatgc gcaccgcctg
   124141 gaaggtacgg gtcgcgggat gtttaaactt atctttcacc ggcgttgcag cagccacgac
   124201 ttccgccagt tctttggtgc gggtcatcgg ctgttcgcgg ttacgctcga caatggcgcg
   124261 ggcaatgcgt ttggcaaaac gctcttcacc ataggttttc aatacccagg cgatatcggc
   124321 ttcttctgcg gtttgtagcc attcagcggc tgactgccca cgggttgggt ccatacgcat
   124381 gtccagcgga ccatcgcgca taaaggaaaa gccgcgctca gcatcatcaa gttgcggtga
   124441 agagacgcca agatcgagga gaatgccgtc gatcttgccg ataagatcgc gctcggcaac
   124501 gtattcgccc agcgcggaga aaggtccgtg gatgatggag aagcgcggat catcaatagt
   124561 cttcgcaacg gcgatagcct gcgggtcgcg atcgatcgcc agcaaacgcc cctcttcgcc
   124621 aagctgcgag aggatcagac gtgagtgacc accgcgacca aaagtcccat caatgtagat
   124681 gccatcagga cggatattga ggccattaac ggcttcatcc agcagcaccg tagtatgttt
   124741 atagttttcc atcattttat agagacaagt cctgcagtcg ctccgataag tctccggtag
   124801 ccaactgctc tgcgtcgata tcttccttga cctgttgatg ccaggttgtt tcatcccaca
   124861 gctcaaactt gttgaactgt ccaaccagca tcacttcttt tgtcagcccg gcatgttgcc
   124921 gcagtactgg cgcgattaac aatcgacctg cgccatccat ctgacattcg ctggcatgac
   124981 ctaacagtag gcgctgcaca cggcgctcaa ccgggttcat gctcgacaga cgcgataatt
   125041 tttgctcgat aatttcccat tcaggcaggg ggtaaagcag caggcacggg tgatgaatgt
   125101 caatggtgca aaccatttga ccggcagcgt tctcaagcag ctgttcccgg taacgggtag
   125161 gcactgataa gcgccctttg ctgtcgagat tgactaacgt tgctccccgg aacatgccag
   125221 cctcacccct tattcccact ttgccccaca atttcccact gaaaggagtt tacggagcgg
   125281 aggaaaagct tgtcaagcca gtcacaaggc ataccgaggt aaaaaacccg atgtttacgg
   125341 ctaatatcag cgttgtttat tttacgtcca acgtgcgcag caaattaacg ttatgaatag
   125401 ctgtaagaaa aaatccctca tcgtcatcac cgttttaaaa tgactcacta ttttccacag
   125461 caaatataaa gtgtcagttt gcgacgcgag cggcatttta ggacatatct tccccggtta
   125521 acagtccctg ttgcgtctgt gtggcgcttg atgccagcgg gtttgcgcaa aagcaaagaa
   125581 aagtgcttgt taaatcggca attcatctct gcatgtaaca aaataatgca aaaacgcgct
   125641 gtcgatatca cttaattatt gtgaatttca gctggtgagt taattaacgg gcgggtttaa
   125701 aagaacttat caataatagt caggaatagt cttatttact ttaaggatat tgatgtccat
   125761 tcccgtactc tacgcgccag agggaaattc acctggcgcg tatttttgtt cgcggcttag
   125821 ctacggctga gcacaccgcg gcgatagaga ttacgtttaa tgcgcgttaa accaggtttt
   125881 ggcttacgcg gttcgtccag gcttgccagg acaatctcca gcacacgctc tgcgacatcg
   125941 cggtgacgtt gagccactgc cagcaccggg cactgtaaga agtcgagcag ttcgttatcg
   126001 ccaaaggtgg caattgccag gtcagaaggc agtttaccat cgcgacgtag cgtgacatcc
   126061 atcacccctt gcaacaacgc aaacgacgtt gtgaacagcg cctgcggcat cggatgcgtt
   126121 tccagccatt tttcgaataa ctgggcagcc gcctcccgct catagctgtt ggcatacagg
   126181 aaatgcactt cgcgcggatc atctttccag gcagtacgga aaccttgttc acgcaggaag
   126241 ctgacagaaa gctccggcag cgcgccaaga taaagcaccg tctcggcggg aaacttacgt
   126301 aactcttccg ccagcatttc ggcatcatcc tgatcggcac caaccacgct ggtgaaatgt
   126361 tcacgatcga gggcgcggtc cagcgcgaca atcgggaacg ggtcgttagc ccagcgttga
   126421 taaaaaggat gctcaggtgg caacgacgtc gaaacaataa tggcatcaac ctgacgctgt
   126481 aaaaggtgct caatgcagcg catttcgttg tctggctgat cttctgagca ggcaatcagc
   126541 agttgataac cccgttgccg cgcctggcgc tcaagatagt tagcgatgcg ggtatagctg
   126601 gtgttctcca gatcggggat cacaagacca atagaacgtg tgcgtccagc acgaagccca
   126661 gctgccacgg cgttcgggtg gtaattgtgc tcacgcacca cagccatgac tttttcaacg
   126721 gttttgtcgc tcacacggta ttgcttcgct ttgccgttaa taacatagct tgcagtggtc
   126781 cgcgacactc ccgccagccg agcgatttca tccagtttca caattgcccc ttgcgtaaaa
   126841 tgtaaaaacc atagccattg tactggtatg ggttaaattc attaacatct aagcgcagaa
   126901 aattaactgc ggcaactgct tttattccag gttcccactg atttcgcaaa aaaagcccaa
   126961 cgtgacatgt tgggctgcaa attgcgcact gagatcattc tcaacgcatt attttatcgc
   127021 cgcgcgaaag tccgaccaca ccagagcgag caacttccac aattttcgcc acatcgcgaa
   127081 tcgatgctaa aaatgcatca agcttatcgc tggtgcctgc taattgaacg gtataaagcg
   127141 agggggtgac atcgataatt tgcccacgga atatttccgt attacgtttc acttcgtcac
   127201 gcccgtaacc gctggcctga attttcacca gcatgatttc ccgctcaaca tgcgcgccct
   127261 gccccaactc actcacgcgc aagacatcga ccagcttgtg taattgcttt tcgatctgct
   127321 caagcacttt ttcatcgccc acggtctgga tggtcatacg cgataatgtc ggatcgtcgg
   127381 ttggcgcaac ggtcaggctt tcaatgttgt agccacgctg ggaaaaaagg ccaatcacgc
   127441 gggataacgc gcctgattca ttttcgagta agactgataa tatccggcgc ataatcaggt
   127501 tctctccgtt ttgcttaacc acatttcatc cattccgccc ccgcgaatct gcatcgggta
   127561 gacgtgctca ctgccatcga cggtaacatc aacaaacacc aggcgattat tgcacacctg
   127621 ttccagcgcc tcgctaagtt tgctttccag ctcatgcgga tgagagatct ggatcccgac
   127681 gtgaccatag gcttccgcca gacggacgaa atcgggtagt gattgcatat aagattgtga
   127741 atgacggccg gaatagatca tgtcctgcca ctgtttcacc atccccagat agcggttatt
   127801 gagattcacc accagtaccg gcaactcgta ttgcaacgcg gtagacagtt cctggatgtt
   127861 catctgaata ctgccgtcgc cagtgacgca aaccacggtt tcttctggca acgccatttt
   127921 gacgcccagt gccgcaggta aaccaaaacc catcgtgccg aggccaccgg aattgatcca
   127981 gcgacgcggt ttgtcgaatg gataataaag tgcagcaaac atctggtgct gcccgacatc
   128041 ggacgtcacg taagcgtctc ccttcgtcaa ccgccaaaga gtctcgatca ccgcctgcgg
   128101 tttaatcttt tcactgtgag tgtcatattt caggcactga cgagcgcgcc actgttcaat
   128161 ttgctgccac cagtcgcgga tctcatccag tggttgatgg gcggattctt gcgacaagag
   128221 ttcaagcatt tgttcgagga cctggcgagc atcccccaca atcgggatat ccgcagtcac
   128281 ggttttagaa atggaagtag gatcaatatc gatatgcaga acagtggcat ttgggcagta
   128341 ctttgccaga ttgttcgtcg ttcggtcatc aaatcgtacc ccgacggcga aaatcacatc
   128401 cgcgttatgc atcgtcatat tggcttcgta ggtaccgtgc attcccagca tgcccagcgc
   128461 ctgacgatgc gttgccggaa acgcccccag ccccatcaat gaggaaacaa cgggcagatt
   128521 caacgcctcc accgtttctt tcaactgctg atggcagccc gccatgattg ccccaccgcc
   128581 tacgtagaca accggttttt ttgccgctac cagcgtttgc agagcgcgct taatttgccc
   128641 tttatgtccg gtagtagtgg gattgtaaga acgcatactg accgactcag gccagacata
   128701 gggtaatttg ttcgccggat taagaatatc tttcggtaaa tcaacgacca ctggtcctgg
   128761 gcgaccactt gccgccagcc agaaagcctt tttcagcacc tgcggaatgt cttccgtttg
   128821 cttaaccaga aaactgtgtt taaccaccgg tcgcgaaatc cccaccatgt cgcactcctg
   128881 aaaggcatcg taacctatca acgaggtcgc tacctgcccg gaaaggacaa ctaatggaat
   128941 ggaatccata taagcggtgg cgatgccggt aatcgcattg gtcgcccctg gacccgacgt
   129001 taccagcacg acgccgactt ccccggtcgc gcgcgccaga ccatcggcca tatgcactgc
   129061 cgcctgctca tgacgaacta aaacatgatc gataccaccc acggtatgca atgcatcgta
   129121 aatatcaagg actgcgcctc cgggataacc gaatacttgt ttaacgccct gatcgataag
   129181 cgatcggacg accatctcgg ctccagacaa catctccatg gcctgcctca ctgtttgacg
   129241 gaaaaaatgt gtaaaacaca ttaaccgtcc gatcttgctt aagcaattgg cagcaagaga
   129301 cataaacgca gggtaataag aataaacagg aggaaaggtg aaaagaaacg ataaaatcct
   129361 ccattacgaa ggattaaatt gataataaat cggctgaatc ccacaactta cagcaatttc
   129421 tctatttttt taattaatcc taaaacagag agcccacaca ttcagaataa aattctacat
   129481 tcaataaaaa atacagaata aaccagacat tcatgcctga cctattctgc attcagttag
   129541 cgtttgcaaa ttgagactaa ttgctcttcc atccactgat ggcctttatc gcgcccggca
   129601 gcttcatgcc aggagagata acaggttctg ctattttgtt ttaacggcag cggtaatacc
   129661 tgtaattcta aggattcagc gaactcttca gccagccaac gcggcgcaat agcgaccaaa
   129721 tgcgtttgcg acaccacgct aagtacgctc atcattgcca tgccctgata cgcgatactg
   129781 gcttgcttat ctaccgtgtc ataccaaggt tgactaaatg acgcgaaacg atcgagcgaa
   129841 accgccgcat gttgttcgtt ataaacatca tgtttcagta acgggccctt aattgttgga
   129901 tgatttttgc tggctaccag caccatttca tctttaaata atggcacgct ggtaaattca
   129961 ggacgatgga agtcttcata actaatcaca aactccgttt cctgataacg cagctgatgt
   130021 tcagtgttct gatttaatga agacttgaac ataacatgta tatttggcgc aatctgctca
   130081 atgtgattat aaatctgcga ggtcagaatg ctgtctaacg ggctgcaaac acaaagatga
   130141 aatacacgtt cactgctcgc gggttcaaaa cctgaaccag gcaattcatt ttgtactagt
   130201 tgcaatgcct gacgaactga gccaaaaagt tgaaatgcgc gagcagtcgg ttgaatacca
   130261 cggccataac gaacaaaaag ctcgtcatta aacatcacct tcaggcgtgc aacagcgtta
   130321 ctgaccgcag gttgcgacat acccagaaca tgagcggcac gggtaatgtt ttgctcctgc
   130381 atcacggcat cgaaaacggt taataagttg agatcgacca tgcgtagctg tggcttgctt
   130441 aactccgccg tctctgaatg atctgtttgt acctctggca tacttaactc cactgtcaca
   130501 cttaactccc tttcccttat tggaatgcag agaaataatc ctgaagaata tgatttatca
   130561 tgcatataaa ataagaaaaa gcaaaatgag taaaattcgg aaaacataaa gatacgggtt
   130621 ctgataaaaa cagaatccat tgccgtggaa tgagtcattt accacagcat aataatccat
   130681 aatatttttg ttgcgaaaac aatctaatca taactaccgc ga
//
LOCUS       DAZUDJ010000003       129071 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.003, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000003 DAZUDJ010000000
VERSION     DAZUDJ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 129071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 129071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..129071
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.003"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            9..593
                     /gene="yraH"
                     /locus_tag="ACHY1N_000250"
     CDS             9..593
                     /gene="yraH"
                     /locus_tag="ACHY1N_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4042611.1"
                     /translation="MNKVTKTAIVGLLALFAGNAAATDGEIVFDGEILKSACEINDSD
                     KKIEVALGHYNAEQFRSVGDRSPKIPFTIPLVNCPVTGWEHDNGNVEASFRLWLETRD
                     NGTVPNFPNLAKVGSFAGTAATGVGIRIDDAESGNLMPLNAMGNDNTVYQIPADSNGI
                     VNVDLIAYYVSTVEASEITPGEADAVVNVTLDYR"
     gene            673..1368
                     /gene="yraI"
                     /locus_tag="ACHY1N_000251"
     CDS             673..1368
                     /gene="yraI"
                     /locus_tag="ACHY1N_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0061077 - chaperone-mediated protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HFS4042612.1"
                     /translation="MSKRTFAVIITLLCSFCIGQALAGGIVLQRTRVIYDASRKEAAL
                     PVANKGAETPYLLQSWVDNIDGTSRAPFIITPPLFRLEAGDDSSLRIIKTADNLPENK
                     ESLFYINVRAIPAKKKSDDVNANELTLVFKTRIKMFYRPAHLKGRVNDAWTSLEFKRS
                     DHSLNIYNPTEYYVVFAGLAVDKTDLTSKIEYIAPGEHKQLPLPASGGKNVKWAAIND
                     YGGSSGTETRPLQ"
     gene            1398..3914
                     /gene="yraJ"
                     /locus_tag="ACHY1N_000252"
     CDS             1398..3914
                     /gene="yraJ"
                     /locus_tag="ACHY1N_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015473 - fimbrial usher porin activity
                     [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HFS4042613.1"
                     /translation="MPQRHHQGHKRTPKQLALIIKRCLPMVLTGSGMLCTTANAEEYY
                     FDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQKKITFTANAEQLL
                     QPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDFNHQRLNLSIPQ
                     IALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNMQNGANFGPW
                     RLRNYSTWTRNDQASSWNTISSYLQRDIKALKSQLLLGESATSGSIFSSYTFTGVQLA
                     SDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVPAGAFEINDLYPSSNSG
                     DLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDSKEPEFAEAT
                     AIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDNQHSFHGY
                     QWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFNEANTRNWNYNSRQKSEIQFNISQTI
                     FDGVSLYASGSQQDYWGNNEKNRNISVGVSGQQWGIGYSLNYQYSRYTDQNNDRALYL
                     NLSIPLERWLPRSRVSYQMTSQKDRPTQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHN
                     SSLNASYRSPYGTFSAGYSYGNDSSQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDAN
                     GASGVRIQNYPGIATDPFGYAVVPYLTTYQENRLSVDTTQLPDNVDLEQTTQFVVPNR
                     GAMVAARFNANIGYRVLVTVSDRNGKPLPFGALASNDETGQQSIVDEGGILYLSGISS
                     KSQSWTVRWGNQADQQCQFAFSTPDSEPTTSVLQGTAQCH"
     gene            3925..5016
                     /gene="yraK"
                     /locus_tag="ACHY1N_000253"
     CDS             3925..5016
                     /gene="yraK"
                     /locus_tag="ACHY1N_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4042614.1"
                     /translation="MKRAPLITGLLLISTSCAYASSGGCGADSTSGATNYSSVVDDVT
                     VNQTDNVTGREFTSATLSSTNWQYACTCSAGKAVKLVYMVSPVLTTTGHQAGYYKLND
                     SLDIKTTLQANDIPGLVTDQTVSVNTRFTQIKSNTVYSAATQTGVCQGDTSRYGPVNI
                     GANTTFTLYVTKPFLGSMTIPKTDIAVIKGAWVDGMGSPSTGDFHDLVKLSIQGNLTA
                     PQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTSKIKNSLQMR
                     IDGTTGVVDQYNLVARRRSSDNAPDVGIRIENLGGGVANIPFQNGILPVDPSGHGTIN
                     MRAWPVNLVGGELETGKFQGTATITVIVR"
     gene            complement(5059..5919)
                     /gene="rsmI"
                     /locus_tag="ACHY1N_000254"
     CDS             complement(5059..5919)
                     /gene="rsmI"
                     /locus_tag="ACHY1N_000254"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFS4042615.1"
                     /translation="MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGICVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVK
                     EDENRRKGEMVLIIEGHKAQEEDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALEQQG"
     gene            5983..7971
                     /gene="lpoA"
                     /locus_tag="ACHY1N_000255"
     CDS             5983..7971
                     /gene="lpoA"
                     /locus_tag="ACHY1N_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoA"
                     /protein_id="HFS4042616.1"
                     /translation="MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTTQ
                     ADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELFNQLPQELNDSQRREKT
                     LLAVEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIA
                     QEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDP
                     DMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTI
                     QQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQ
                     PAPVSTPAATTTAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNV
                     EELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIP
                     RSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGTPITPRATT
                     DDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATLYASSRSAQGTAGPDFR
                     LEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMGVDAWSLANHFSQMRQV
                     QGFEINGNTGSLTANPDCVINRKLSWLQYQQGQVVPAS"
     gene            7929..8324
                     /gene="yraN"
                     /locus_tag="ACHY1N_000256"
     CDS             7929..8324
                     /gene="yraN"
                     /locus_tag="ACHY1N_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HFS4042617.1"
                     /translation="MATVPTRSGSPRQLTTKQTGDAWEVQARRWLEGKGLRFVAANVN
                     ERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGS
                     FDTVDCRFDVVAFTGNEVEWIKDAFNDHS"
     gene            8344..8934
                     /gene="diaA"
                     /locus_tag="ACHY1N_000257"
     CDS             8344..8934
                     /gene="diaA"
                     /locus_tag="ACHY1N_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001483830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HFS4042618.1"
                     /translation="MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV"
     gene            8944..9519
                     /gene="dolP"
                     /locus_tag="ACHY1N_000258"
     CDS             8944..9519
                     /gene="dolP"
                     /locus_tag="ACHY1N_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006970 - response to osmotic stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/outer membrane stress-associated
                     lipid-binding lipoprotein"
                     /protein_id="HFS4042619.1"
                     /translation="MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVD
                     GANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMG
                     LVTEREAKAAADIASRVSGVKRVTTAFTFIK"
     gene            complement(9633..10673)
                     /gene="yraQ"
                     /locus_tag="ACHY1N_000259"
     CDS             complement(9633..10673)
                     /gene="yraQ"
                     /locus_tag="ACHY1N_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFS4042620.1"
                     /translation="MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWQPYYGKAFTA
                     AETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLR
                     TLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPVLNPAT
                     LVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFS
                     RWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVMAMAVAGCLFVI
                     PTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAV
                     SGVIVGGLALLF"
     gene            complement(10746..11381)
                     /gene="yraR"
                     /locus_tag="ACHY1N_000260"
     CDS             complement(10746..11381)
                     /gene="yraR"
                     /locus_tag="ACHY1N_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312060.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HFS4042621.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGV
                     FNPHDPQLTDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
                     TLFAPLFRLLPGNWKSIDARDVARVMLAEAMRPGHEGVTILSSSELRKRAE"
     gene            11509..12027
                     /gene="yhbO"
                     /locus_tag="ACHY1N_000261"
     CDS             11509..12027
                     /gene="yhbO"
                     /locus_tag="ACHY1N_000261"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HFS4042622.1"
                     /translation="MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVK
                     GKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGA"
     gene            complement(12007..12450)
                     /gene="yhbP"
                     /locus_tag="ACHY1N_000262"
     CDS             complement(12007..12450)
                     /gene="yhbP"
                     /locus_tag="ACHY1N_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HFS4042623.1"
                     /translation="METLITISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFY
                     ILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYN
                     RRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRGSGTEQA"
     gene            12501..12803
                     /gene="yhbQ"
                     /locus_tag="ACHY1N_000263"
     CDS             12501..12803
                     /gene="yhbQ"
                     /locus_tag="ACHY1N_000263"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage response exodeoxyribonuclease YhbQ"
                     /protein_id="HFS4042624.1"
                     /translation="MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKG
                     ELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAESAGFAELLSSLQTPEIKSD"
     gene            complement(12790..13293)
                     /gene="yhbS"
                     /locus_tag="ACHY1N_000264"
     CDS             complement(12790..13293)
                     /gene="yhbS"
                     /locus_tag="ACHY1N_000264"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4042625.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEY
                     HEHFNRF"
     gene            complement(13287..13811)
                     /gene="ubiT"
                     /locus_tag="ACHY1N_000265"
     CDS             complement(13287..13811)
                     /gene="ubiT"
                     /locus_tag="ACHY1N_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HFS4042626.1"
                     /translation="MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQA
                     LDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMK
                     TAPETKQTSVGEPC"
     gene            14020..15015
                     /gene="ubiU"
                     /locus_tag="ACHY1N_000266"
     CDS             14020..15015
                     /gene="ubiU"
                     /locus_tag="ACHY1N_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFS4042627.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPL
                     EVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKADPQNFIPQSAWMETLGSMSEGTQTTLGAYHRKWQ"
     gene            15024..15902
                     /gene="ubiV"
                     /locus_tag="ACHY1N_000267"
     CDS             15024..15902
                     /gene="ubiV"
                     /locus_tag="ACHY1N_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFS4042628.1"
                     /translation="MKYSLGPVLWYWPKETLEDFYQQAATSSADVIYLGEAICSKRRA
                     TKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNM
                     CAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRN
                     QFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLN
                     GIQTMSGYVYNLGNELASMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANS
                     DCNGYWRRLAGLELQA"
     gene            16108..17115
                     /gene="yhbW"
                     /locus_tag="ACHY1N_000268"
     CDS             16108..17115
                     /gene="yhbW"
                     /locus_tag="ACHY1N_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="luciferase-like monooxygenase"
                     /protein_id="HFS4042629.1"
                     /translation="MTDKTIAFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLY
                     PGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELAMDVKEELL
                     G"
     gene            complement(17233..18477)
                     /gene="mtr"
                     /locus_tag="ACHY1N_000269"
     CDS             complement(17233..18477)
                     /gene="mtr"
                     /locus_tag="ACHY1N_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015173 - aromatic amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015801 - aromatic amino acid transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HFS4042630.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPKTIVKCLVYGTLMALALYTIWLLATMGNIPRPEFIGIAEKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSALGRLKTALLTFAPPV
                     VGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMITLIL
                     VFGVGNALVHILSSFNLLPVYQ"
     gene            complement(18631..20520)
                     /gene="deaD"
                     /locus_tag="ACHY1N_000270"
     CDS             complement(18631..20520)
                     /gene="deaD"
                     /locus_tag="ACHY1N_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="HFS4042631.1"
                     /translation="MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGR
                     DVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPH
                     TGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRR
                     FGGDA"
     gene            complement(20513..20593)
                     /gene="yrbN"
                     /locus_tag="ACHY1N_000271"
     CDS             complement(20513..20593)
                     /gene="yrbN"
                     /locus_tag="ACHY1N_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HFS4042632.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(20700..21584)
                     /gene="nlpI"
                     /locus_tag="ACHY1N_000272"
     CDS             complement(20700..21584)
                     /gene="nlpI"
                     /locus_tag="ACHY1N_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HFS4042633.1"
                     /translation="MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(21693..23828)
                     /gene="pnp"
                     /locus_tag="ACHY1N_000273"
     CDS             complement(21693..23828)
                     /gene="pnp"
                     /locus_tag="ACHY1N_000273"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFS4042634.1"
                     /translation="MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQN
                     INELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSE
                     TIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRV
                     YTGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRIRLSIKEATEQSQPAAAPEAPAAEQGE"
     gene            complement(24075..24344)
                     /gene="rpsO"
                     /locus_tag="ACHY1N_000274"
     CDS             complement(24075..24344)
                     /gene="rpsO"
                     /locus_tag="ACHY1N_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFS4042635.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR"
     gene            complement(24493..25437)
                     /gene="truB"
                     /locus_tag="ACHY1N_000275"
     CDS             complement(24493..25437)
                     /gene="truB"
                     /locus_tag="ACHY1N_000275"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFS4042636.1"
                     /translation="MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVT
                     FSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEH
                     LRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAP
                     LEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(25437..25838)
                     /gene="rbfA"
                     /locus_tag="ACHY1N_000276"
     CDS             complement(25437..25838)
                     /gene="rbfA"
                     /locus_tag="ACHY1N_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFS4042637.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMS
                     RDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTSVVKHDEERRVNPDDSKED"
     gene            complement(26002..28674)
                     /gene="infB"
                     /locus_tag="ACHY1N_000277"
     CDS             complement(26002..28674)
                     /gene="infB"
                     /locus_tag="ACHY1N_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFS4042638.1"
                     /translation="MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQT
                     LIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERL
                     AAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSN
                     QQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDN
                     AEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADRE
                     EARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIK
                     AMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAP
                     VVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAA
                     FTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPD
                     RVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMAS
                     GAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSI
                     PVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMT
                     EGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASN
                     AILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLA
                     EVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVR
                     NGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA"
     gene            complement(28699..30186)
                     /gene="nusA"
                     /locus_tag="ACHY1N_000278"
     CDS             complement(28699..30186)
                     /gene="nusA"
                     /locus_tag="ACHY1N_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFS4042639.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEA
                     VILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGE
                     EVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLW
                     DDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGW
                     ELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKEL
                     LEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGVDRDLAFKLAA
                     RGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMAARNICWFGDEA"
     gene            complement(30214..30666)
                     /gene="rimP"
                     /locus_tag="ACHY1N_000279"
     CDS             complement(30214..30666)
                     /gene="rimP"
                     /locus_tag="ACHY1N_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFS4042640.1"
                     /translation="MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLV
                     LRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(30873..30949)
                     /locus_tag="ACHY1N_000280"
     tRNA            complement(30873..30949)
                     /locus_tag="ACHY1N_000280"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30913..30915),aa:Met,seq:cat)
     gene            31297..32640
                     /gene="argG"
                     /locus_tag="ACHY1N_000281"
     CDS             31297..32640
                     /gene="argG"
                     /locus_tag="ACHY1N_000281"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HFS4042641.1"
                     /translation="MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQG
                     RWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKG
                     DSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENLENKGQ"
     gene            complement(32648..34273)
                     /gene="yhbX"
                     /locus_tag="ACHY1N_000282"
     CDS             complement(32648..34273)
                     /gene="yhbX"
                     /locus_tag="ACHY1N_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417641.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HFS4042642.1"
                     /translation="MTVFNKFARSFKSHWLLYLCVIVFGITNLVASSGAHMVQRLLFF
                     VLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDP
                     DEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQ
                     FAYKDAKNKKAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVR
                     DTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVP
                     LSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETV
                     YVRGFDELLLPHLSQALQQKTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDAC
                     YDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHV
                     PMFIWYSPVLGDGVDRTTENDIFSTAYNNYLINAWMGVTKPEQPQTLEEVIAHYKGDS
                     RVVDANHDVFDYVMLRKEFTEDKQGNPTPEGQG"
     gene            complement(34730..34816)
                     /locus_tag="ACHY1N_000283"
     tRNA            complement(34730..34816)
                     /locus_tag="ACHY1N_000283"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34780..34782),aa:Leu,seq:gag)
     gene            complement(34831..35163)
                     /gene="secG"
                     /locus_tag="ACHY1N_000284"
     CDS             complement(34831..35163)
                     /gene="secG"
                     /locus_tag="ACHY1N_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFS4042643.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG
                     SSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPA
                     KPTSDIPN"
     gene            complement(35391..36728)
                     /gene="glmM"
                     /locus_tag="ACHY1N_000285"
     CDS             complement(35391..36728)
                     /gene="glmM"
                     /locus_tag="ACHY1N_000285"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFS4042644.1"
                     /translation="MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
                     FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVG
                     ATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVK
                     AVTAEVEAALGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV"
     gene            complement(36721..37569)
                     /gene="folP"
                     /locus_tag="ACHY1N_000286"
     CDS             complement(36721..37569)
                     /gene="folP"
                     /locus_tag="ACHY1N_000286"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312083.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HFS4042645.1"
                     /translation="MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHA
                     NLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAIAQRFEVWISVDTSKPEV
                     IRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGM
                     SRKSMIGQLLNVVPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAK
                     ENKRYE"
     gene            complement(37659..39593)
                     /gene="ftsH"
                     /locus_tag="ACHY1N_000287"
     CDS             complement(37659..39593)
                     /gene="ftsH"
                     /locus_tag="ACHY1N_000287"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFS4042646.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNND
                     QVREARINGREINVTKKDSNRYTTYIPVQDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGPEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQLLTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARRDVRPPAGWEEPGASNNSGDNGSPKAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(39693..40322)
                     /gene="rlmE"
                     /locus_tag="ACHY1N_000288"
     CDS             complement(39693..40322)
                     /gene="rlmE"
                     /locus_tag="ACHY1N_000288"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016436 - rRNA (uridine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HFS4042647.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP"
     gene            40448..40741
                     /gene="yhbY"
                     /locus_tag="ACHY1N_000289"
     CDS             40448..40741
                     /gene="yhbY"
                     /locus_tag="ACHY1N_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFS4042648.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHH
                     ELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(40897..41373)
                     /gene="greA"
                     /locus_tag="ACHY1N_000290"
     CDS             complement(40897..41373)
                     /gene="greA"
                     /locus_tag="ACHY1N_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFS4042649.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL"
     gene            41621..43054
                     /gene="dacB"
                     /locus_tag="ACHY1N_000291"
     CDS             41621..43054
                     /gene="dacB"
                     /locus_tag="ACHY1N_000291"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004185 - serine-type carboxypeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HFS4042650.1"
                     /translation="MRFSRFIIGLTSCIAFSVQAANVDEYVTQLPAGANLALMVQKVG
                     ASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLV
                     ARFGADPTLKRQDIRNMVATLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCF
                     SAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCE
                     LDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGITWSGTLLR
                     QTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHARFNVPGTWRAGSD
                     AVRQILRQQAGVDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     EPADQRNRRIPLVRFESRLYKDIYQNN"
     gene            complement(43094..44266)
                     /gene="cgtA"
                     /locus_tag="ACHY1N_000292"
     CDS             complement(43094..44266)
                     /gene="cgtA"
                     /locus_tag="ACHY1N_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HFS4042651.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAK
                     PRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIE
                     NPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR"
     gene            complement(44282..45247)
                     /gene="yhbE"
                     /locus_tag="ACHY1N_000293"
                     /pseudo
     CDS             complement(44282..45247)
                     /gene="yhbE"
                     /locus_tag="ACHY1N_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
     gene            complement(45374..45631)
                     /gene="rpmA"
                     /locus_tag="ACHY1N_000294"
     CDS             complement(45374..45631)
                     /gene="rpmA"
                     /locus_tag="ACHY1N_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFS4042652.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTK
                     FHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE"
     gene            complement(45652..45963)
                     /gene="rplU"
                     /locus_tag="ACHY1N_000295"
     CDS             complement(45652..45963)
                     /gene="rplU"
                     /locus_tag="ACHY1N_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFS4042653.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            46222..47193
                     /gene="ispB"
                     /locus_tag="ACHY1N_000296"
     CDS             46222..47193
                     /gene="ispB"
                     /locus_tag="ACHY1N_000296"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HFS4042654.1"
                     /translation="MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGG
                     KRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNA
                     DGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVQEAMN
                     ACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRDR"
     gene            47421..47699
                     /gene="sfsB"
                     /locus_tag="ACHY1N_000297"
     CDS             47421..47699
                     /gene="sfsB"
                     /locus_tag="ACHY1N_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HFS4042655.1"
                     /translation="MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSR
                     PWPKGEMIIVKALGTDPWVIWPSRYHDPQTHEFIDRTQLMRSYTKPKK"
     gene            complement(47747..49006)
                     /gene="murA"
                     /locus_tag="ACHY1N_000298"
     CDS             complement(47747..49006)
                     /gene="murA"
                     /locus_tag="ACHY1N_000298"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFS4042656.1"
                     /translation="MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVA
                     RFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(49061..49315)
                     /gene="ibaG"
                     /locus_tag="ACHY1N_000299"
     CDS             complement(49061..49315)
                     /gene="ibaG"
                     /locus_tag="ACHY1N_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HFS4042657.1"
                     /translation="MENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(49475..49768)
                     /gene="mlaB"
                     /locus_tag="ACHY1N_000300"
     CDS             complement(49475..49768)
                     /gene="mlaB"
                     /locus_tag="ACHY1N_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HFS4042658.1"
                     /translation="MSESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDL
                     SRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR"
     gene            complement(49768..50403)
                     /gene="mlaC"
                     /locus_tag="ACHY1N_000301"
     CDS             complement(49768..50403)
                     /gene="mlaC"
                     /locus_tag="ACHY1N_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HFS4042659.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKN
                     EQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQYYKSATPAQREAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGN
                     WQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK"
     gene            complement(50422..50973)
                     /gene="mlaD"
                     /locus_tag="ACHY1N_000302"
     CDS             complement(50422..50973)
                     /gene="mlaD"
                     /locus_tag="ACHY1N_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015914 - phospholipid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HFS4042660.1"
                     /translation="MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYA
                     TFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLPRVTLEIEQRYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNK
                     NSGDAPAAAPGNNETTEPVGTTK"
     gene            complement(50978..51760)
                     /gene="mlaE"
                     /locus_tag="ACHY1N_000303"
     CDS             complement(50978..51760)
                     /gene="mlaE"
                     /locus_tag="ACHY1N_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HFS4042661.1"
                     /translation="MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTV
                     IFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISL
                     FNGYDAIPTSAGISRATTRTVVHSSLAVLGLDFVLTALMFGN"
     gene            complement(51768..52577)
                     /gene="mlaF"
                     /locus_tag="ACHY1N_000304"
     CDS             complement(51768..52577)
                     /gene="mlaF"
                     /locus_tag="ACHY1N_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HFS4042662.1"
                     /translation="MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIL
                     ADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPFRYPAGDYHADLLPGS"
     gene            52787..53764
                     /gene="yrbG"
                     /locus_tag="ACHY1N_000305"
     CDS             52787..53764
                     /gene="yrbG"
                     /locus_tag="ACHY1N_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HFS4042663.1"
                     /translation="MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEIIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLR
                     RELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTR
                     EQLAELPRDGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAI
                     GTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAYSRDY
                     SVMLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPILVE"
     gene            53778..54764
                     /gene="kdsD"
                     /locus_tag="ACHY1N_000306"
     CDS             53778..54764
                     /gene="kdsD"
                     /locus_tag="ACHY1N_000306"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HFS4042664.1"
                     /translation="MSHVELQPGFDFQQAGKEVLAIERECLAELEQYINQNFTLACEK
                     MFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEITALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVAKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPH
                     VKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADV
                     MTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV"
     gene            54785..55351
                     /gene="kdsC"
                     /locus_tag="ACHY1N_000307"
     CDS             54785..55351
                     /gene="kdsC"
                     /locus_tag="ACHY1N_000307"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HFS4042665.1"
                     /translation="MSKAGASLATCYGPVSADVMAKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSDIEVAIITGRKAKLVEDRCATLGITHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTRIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            55348..55923
                     /gene="lptC"
                     /locus_tag="ACHY1N_000308"
     CDS             55348..55923
                     /gene="lptC"
                     /locus_tag="ACHY1N_000308"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HFS4042666.1"
                     /translation="MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKS
                     EHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAK
                     LTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            55892..56449
                     /gene="lptA"
                     /locus_tag="ACHY1N_000309"
     CDS             55892..56449
                     /gene="lptA"
                     /locus_tag="ACHY1N_000309"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HFS4042667.1"
                     /translation="MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQS
                     LDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNG
                     KPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
                     TTVLVPSQLQDKNNKGQTPAQKKGN"
     gene            56456..57181
                     /gene="lptB"
                     /locus_tag="ACHY1N_000310"
     CDS             56456..57181
                     /gene="lptB"
                     /locus_tag="ACHY1N_000310"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HFS4042668.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAV
                     LQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            57229..58662
                     /gene="rpoN"
                     /locus_tag="ACHY1N_000311"
     CDS             57229..58662
                     /gene="rpoN"
                     /locus_tag="ACHY1N_000311"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFS4042669.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESN
                     PLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPEELPLDASWDTIYTAGTPSGTSG
                     DYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDDTGYLTVPLED
                     ILESMGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARL
                     IISDHLDLLANHDFRTLMRVTRLKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDDDSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            58685..58972
                     /gene="hpf"
                     /locus_tag="ACHY1N_000312"
     CDS             58685..58972
                     /gene="hpf"
                     /locus_tag="ACHY1N_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HFS4042670.1"
                     /translation="MQLNITGNNVEITEALREFVTAKFAKLEQYFDRINQVYVVLKVE
                     KVTHTSDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQH"
     gene            59090..59581
                     /gene="ptsN"
                     /locus_tag="ACHY1N_000313"
     CDS             59090..59581
                     /gene="ptsN"
                     /locus_tag="ACHY1N_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HFS4042671.1"
                     /translation="MTNNDTTLQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLS
                     LPPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLEAPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAAQSDEELYQIITDTEGTP
                     DEA"
     gene            59627..60481
                     /gene="rapZ"
                     /locus_tag="ACHY1N_000314"
     CDS             59627..60481
                     /gene="rapZ"
                     /locus_tag="ACHY1N_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFS4042672.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKP"
     gene            60478..60750
                     /gene="npr"
                     /locus_tag="ACHY1N_000315"
     CDS             60478..60750
                     /gene="npr"
                     /locus_tag="ACHY1N_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HFS4042673.1"
                     /translation="MTVKQTVEITNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEVEATGPQEEEALAAVIALFNSGFDED"
     gene            60964..61596
                     /gene="yrbL"
                     /locus_tag="ACHY1N_000316"
     CDS             60964..61596
                     /gene="yrbL"
                     /locus_tag="ACHY1N_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HFS4042674.1"
                     /translation="MIRLSEQSPLGTGRHRKCYAHPEDAQRCIKIVYHRGDGGDKEIR
                     RELKYYAHLGRRLKDWSGIPRYHGTVETDCGTGYVYDVIADFDGKPSITLTEFAEQCR
                     YEEDIAQLRQLLKQLKRYLQDNRIVTMSLKPQNILCHRISESEVIPVVCDNIGESTLI
                     PLATWSKWCCLRKQERLWKRFIAQPALAIALQKDLQPRESKTLALTSREA"
     gene            complement(61593..62321)
                     /gene="mtgA"
                     /locus_tag="ACHY1N_000317"
     CDS             complement(61593..62321)
                     /gene="mtgA"
                     /locus_tag="ACHY1N_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009274 - peptidoglycan-based cell wall
                     [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HFS4042675.1"
                     /translation="MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAV
                     MVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEKA
                     LAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRS
                     RQAWILRQMYQLGGEPFMQQHQLD"
     gene            complement(62318..62971)
                     /gene="elbB"
                     /locus_tag="ACHY1N_000318"
     CDS             complement(62318..62971)
                     /gene="elbB"
                     /locus_tag="ACHY1N_000318"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709007.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HFS4042676.1"
                     /translation="MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQ
                     QVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLS
                     NFATLGSECTVDRELKALAQAMHQAGKPLGFMCIAPAMLPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE"
     gene            complement(63201..65537)
                     /gene="arcB"
                     /locus_tag="ACHY1N_000319"
     CDS             complement(63201..65537)
                     /gene="arcB"
                     /locus_tag="ACHY1N_000319"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HFS4042677.1"
                     /translation="MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     SLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLCFNLEPTLPLPHQV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVTSEQGKGSTFTLTIHAPSV
                     AEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFK
                     PGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDD
                     VLSKPLSVPALTAMIKKFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLI
                     TDGLAVFEKMMPGYVSVLESNLTAQDKKGIVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK"
     gene            complement(65633..66562)
                     /gene="yhcC"
                     /locus_tag="ACHY1N_000320"
     CDS             complement(65633..66562)
                     /gene="yhcC"
                     /locus_tag="ACHY1N_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312117.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFS4042678.1"
                     /translation="MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
                     HDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHI
                     VKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDRYLNEHGVQGSALERPWIPPTE"
     gene            67237..71697
                     /gene="gltB"
                     /locus_tag="ACHY1N_000321"
     CDS             67237..71697
                     /gene="gltB"
                     /locus_tag="ACHY1N_000321"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HFS4042679.1"
                     /translation="MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIV
                     EEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLHDAAPFVNET
                     GSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSRELD
                     DDTLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMKEEHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLP
                     VPAPMAVGAIQTRLVDQSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VGLCFQGAVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYFEFIARE
                     TRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHPGKALYCTEN
                     NPPFDNGLLNAQLLQQAKPFVDERQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     ADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
                     EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCIL
                     GKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLSVDDLAIHEEHLRGLITEHVQ
                     HTGSQRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            71710..73128
                     /gene="gltD"
                     /locus_tag="ACHY1N_000322"
     CDS             71710..73128
                     /gene="gltD"
                     /locus_tag="ACHY1N_000322"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit GltD"
                     /protein_id="HFS4042680.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLA
                     CADVLTRNGVKAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTE
                     VGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGE
                     TRDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEDNMPGSRREVKN
                     AREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPA
                     DAVIMAFGFRPHNMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNWLEV"
     gene            73312..74439
                     /gene="yhcG"
                     /locus_tag="ACHY1N_000323"
     CDS             73312..74439
                     /gene="yhcG"
                     /locus_tag="ACHY1N_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDDEXK nuclease domain-containing protein"
                     /protein_id="HFS4042681.1"
                     /translation="MESLSERTSTGYQQIHDGIIHLVDSARTETVRSVNALMTATYWE
                     IGRRIVEFEQGGEARAAYGAQLIKRLSKDLSLRYKRGFSAKNLRQMRLFYLFFQHVEI
                     RQTVSGELTPLGIPQTPSAEFPSAKIWQTLSAKSFPLPWSTYVRLLSVKNADARSFYE
                     KETLRCGWSVRQLERQIATQFYERTLLSHDKSAMLQQHAPTETHILPQQAIRDPFVLE
                     FLELKDEYSESDFEEALINHLMDFMLELGDDFAFVGRQRRLRIDDNWFRVDLLFFHRR
                     LRCLLIVDLKVGKFSYSDAGQMNMYLNYAKEHWTLPDENPPIGLVLCAEKGAGEAHYA
                     LAGLPNTVLASEYKMQLPDEKRLADELVRTQAVLEEGYRRR"
     gene            complement(74499..74963)
                     /gene="nanQ"
                     /locus_tag="ACHY1N_000324"
     CDS             complement(74499..74963)
                     /gene="nanQ"
                     /locus_tag="ACHY1N_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006974 - DNA damage response [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate anomerase"
                     /protein_id="HFS4042682.1"
                     /translation="MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMTFNTQSPVEKKAELHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQ
                     LCSTIENEQTIILKPGMFAVFMPGEPHKPGCVVGEPGEIKKVVVKVKADLMA"
     gene            complement(74960..75835)
                     /gene="nanK"
                     /locus_tag="ACHY1N_000325"
     CDS             complement(74960..75835)
                     /gene="nanK"
                     /locus_tag="ACHY1N_000325"
                     /EC_number="2.7.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HFS4042683.1"
                     /translation="MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDA
                     LSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIA
                     INDAQAAAWAEYQALEGDVTEMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLAD
                     PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADARTIFTRAGQGDEQAQWLIHRSA
                     RTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHD
                     AGLLGAALLAQGEKL"
     gene            complement(75832..76521)
                     /gene="nanE"
                     /locus_tag="ACHY1N_000326"
     CDS             complement(75832..76521)
                     /gene="nanE"
                     /locus_tag="ACHY1N_000326"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFS4042684.1"
                     /translation="MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQ
                     AGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADII
                     AIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
                     ETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQ
                     WYNTAMKKAVL"
     gene            complement(76569..78059)
                     /gene="nanT"
                     /locus_tag="ACHY1N_000327"
     CDS             complement(76569..78059)
                     /gene="nanT"
                     /locus_tag="ACHY1N_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HFS4042685.1"
                     /translation="MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLAC
                     GFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILY
                     RGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPT
                     GVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYNPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS"
     gene            complement(78168..79061)
                     /gene="nanA"
                     /locus_tag="ACHY1N_000328"
     CDS             complement(78168..79061)
                     /gene="nanA"
                     /locus_tag="ACHY1N_000328"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008747 - N-acetylneuraminate lyase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HFS4042686.1"
                     /translation="MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYV
                     GGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGP
                     VDEKYLPELKALAQQLMQERG"
     gene            complement(79183..79974)
                     /gene="nanR"
                     /locus_tag="ACHY1N_000329"
     CDS             complement(79183..79974)
                     /gene="nanR"
                     /locus_tag="ACHY1N_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417693.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HFS4042687.1"
                     /translation="MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMI
                     RRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
                     SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVS
                     YQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK"
     gene            80354..81721
                     /gene="dcuC"
                     /locus_tag="ACHY1N_000330"
     CDS             80354..81721
                     /gene="dcuC"
                     /locus_tag="ACHY1N_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HFS4042688.1"
                     /translation="MFGIIISVIVLITMGYLILKNYKPQVVLAAAGIFLMMCGVWLGF
                     GGVLDPAKSSGYLIVDIYNEILRMLSNRIAGLGLSIMAVGGYARYMERTGASRAMVSL
                     LSRPLKLIRSPYIILSATYVIGQIMAQFITSASGLGMLLMVTLFPTLVSLGVSRLSAV
                     AVIATTMSIEWGILETNSIFAAQVAGMKIATYFFHYQLPVASCVIISVAISHFFVQRA
                     FDKKDKNINHEQAELKALDNVPPLYYAILPVMPLILMLGSLFLAHIGLMQSELHLVVV
                     MLLSLTVTMFVEFFRKHNLRETMDDVQAFFDGMGTQFANVVTLVVAGEIFAKGLTTIG
                     TVDAVIRGAEHSGLGGIGVMIIMALVIAICAIVMGSGNAPFMSFASLIPNIAAGLHVP
                     AVVMIMPMHFATTLARAVSPITAVVVVTSGIAGVSPFAVVKRTAIPMAVGFVVNMIAT
                     ITLFY"
     gene            complement(81764..82261)
                     /gene="sspB"
                     /locus_tag="ACHY1N_000331"
     CDS             complement(81764..82261)
                     /gene="sspB"
                     /locus_tag="ACHY1N_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HFS4042689.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPME
                     YARDGQIVLNIAPRAVGNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDTSIMNDEEASADNETVMSVIDGDKPDHDDDTHPDDEPPQPPRGGRPA
                     LRVVK"
     gene            complement(82267..82905)
                     /gene="sspA"
                     /locus_tag="ACHY1N_000332"
     CDS             complement(82267..82905)
                     /gene="sspA"
                     /locus_tag="ACHY1N_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein SspA"
                     /protein_id="HFS4042690.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS"
     gene            complement(83300..83692)
                     /gene="rpsI"
                     /locus_tag="ACHY1N_000333"
     CDS             complement(83300..83692)
                     /gene="rpsI"
                     /locus_tag="ACHY1N_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFS4042691.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            complement(83708..84136)
                     /gene="rplM"
                     /locus_tag="ACHY1N_000334"
     CDS             complement(83708..84136)
                     /gene="rplM"
                     /locus_tag="ACHY1N_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFS4042692.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            complement(84355..85482)
                     /gene="zapE"
                     /locus_tag="ACHY1N_000335"
     CDS             complement(84355..85482)
                     /gene="zapE"
                     /locus_tag="ACHY1N_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HFS4042693.1"
                     /translation="MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSRP
                     PAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQR
                     LHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
                     KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTL
                     TQAHLWLSPLNDETRAQMDKLWLALAGAKRENSPTLEINHRPLATMGVENQTLAVSFT
                     TLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVS
                     AEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG"
     gene            85676..86074
                     /gene="zapG"
                     /locus_tag="ACHY1N_000336"
     CDS             85676..86074
                     /gene="zapG"
                     /locus_tag="ACHY1N_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Z-ring associated protein ZapG"
                     /protein_id="HFS4042694.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LDEYREELVSHFARSAELLDTMAHDYRQLYQHMAKSSSSLLPELSAEANPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRTGAKRD"
     gene            86228..87595
                     /gene="degQ"
                     /locus_tag="ACHY1N_000337"
     CDS             86228..87595
                     /gene="degQ"
                     /locus_tag="ACHY1N_000337"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HFS4042695.1"
                     /translation="MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAP
                     MLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEM
                     SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGI
                     KIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESI
                     YLLMR"
     gene            87685..88752
                     /gene="degS"
                     /locus_tag="ACHY1N_000338"
     CDS             87685..88752
                     /gene="degS"
                     /locus_tag="ACHY1N_000338"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HFS4042696.1"
                     /translation="MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETP
                     ASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQSGGI
                     DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVV
                     VMRDDKQLTLQVTIQEYPATN"
     gene            complement(88814..89752)
                     /gene="mdh"
                     /locus_tag="ACHY1N_000339"
     CDS             complement(88814..89752)
                     /gene="mdh"
                     /locus_tag="ACHY1N_000339"
                     /EC_number="1.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030060 - L-malate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HFS4042697.1"
                     /translation="MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK"
     gene            90187..90657
                     /gene="argR"
                     /locus_tag="ACHY1N_000340"
     CDS             90187..90657
                     /gene="argR"
                     /locus_tag="ACHY1N_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HFS4042698.1"
                     /translation="MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL"
     gene            91022..91285
                     /gene="yhcN"
                     /locus_tag="ACHY1N_000341"
     CDS             91022..91285
                     /gene="yhcN"
                     /locus_tag="ACHY1N_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HFS4042699.1"
                     /translation="MKIKTTVAALSVLSVLSFGAFAADSIDAAQAQNREAIGTVSVSG
                     VASSPMDMREMLNKKAEEKGATAYQITEARSGDTWHATAELYK"
     gene            complement(91340..91612)
                     /gene="yhcO"
                     /locus_tag="ACHY1N_000342"
     CDS             complement(91340..91612)
                     /gene="yhcO"
                     /locus_tag="ACHY1N_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HFS4042700.1"
                     /translation="MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMN
                     DVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH"
     gene            complement(91704..93671)
                     /gene="aaeB"
                     /locus_tag="ACHY1N_000343"
     CDS             complement(91704..93671)
                     /gene="aaeB"
                     /locus_tag="ACHY1N_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HFS4042701.1"
                     /translation="MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIW
                     AGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCA
                     IMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQ
                     GMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDT
                     PVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATE
                     EEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTS
                     LAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSR
                     DRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEK
                     LRIWQAPPQVTEPVHRLAGMLHKYQHALTDS"
     gene            complement(93677..94609)
                     /gene="aaeA"
                     /locus_tag="ACHY1N_000344"
     CDS             complement(93677..94609)
                     /gene="aaeA"
                     /locus_tag="ACHY1N_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HFS4042702.1"
                     /translation="MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFS
                     ADVVAIAPDVSGLITQVNVHDNQLVKKGQILFTIDQPRYQKALEEAQADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGS
                     NKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWP
                     AGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG"
     gene            complement(94617..94820)
                     /gene="aaeX"
                     /locus_tag="ACHY1N_000345"
     CDS             complement(94617..94820)
                     /gene="aaeX"
                     /locus_tag="ACHY1N_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump operon protein
                     AaeX"
                     /protein_id="HFS4042703.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            95003..95932
                     /gene="aaeR"
                     /locus_tag="ACHY1N_000346"
     CDS             95003..95932
                     /gene="aaeR"
                     /locus_tag="ACHY1N_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HFS4042704.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDEL
                     QVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK"
     gene            complement(96060..97505)
                     /gene="tldD"
                     /locus_tag="ACHY1N_000347"
     CDS             complement(96060..97505)
                     /gene="tldD"
                     /locus_tag="ACHY1N_000347"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HFS4042705.1"
                     /translation="MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRD
                     SGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
                     GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQ
                     DKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA"
     gene            complement(97661..101461)
                     /gene="yhdP"
                     /locus_tag="ACHY1N_000348"
     CDS             complement(97661..101461)
                     /gene="yhdP"
                     /locus_tag="ACHY1N_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709041.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein YhdP"
                     /protein_id="HFS4042706.1"
                     /translation="MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKI
                     ESATGMPVEASQLSASWQNFGPTLEAHDIRAELKDGGEFSVKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLRFRTNTPITSGGSDDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSG
                     QRAELAIPQLTWLNDPRRHRAEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQ
                     ADDIDLKPWLGKWMQDNIALETAQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKET
                     HTLSVDNLTAHITRENPGWQFSIPDTRITMDGKPWPSGALTLAWIPEQDVGGKDNKRS
                     DELRIRASNLELAGLEGIRPLAAKLSPALGDVWRSTQPSGKINTLALDIPLQAADNTR
                     FQASWSDLAWKQWKLLPGAEHFSGTLSGSVENGLLTASMKQAKMPYETVFRAPLEIAD
                     GQATISWLNNDKGFQLDGRNIDVKAKAVHARGGFRYLQPANDEPWLGILAGISTDDGS
                     QAWRYFPENLMGKDLVDYLSGAIQGGEADNATLVYGGNPQLFPYKHNEGQFEVLVPLR
                     NAKFAFQPDWPALTNLDIELDFINDGLWMKTDGVNLGGVRASNLTAVIPDYSKEKLLI
                     DADIKGPGKAVGPYFDETPLKDSLGATLQELQLDGDVNARLHLDIPLNGELVTAKGEV
                     TLRNNSLFIKPLDSTLKNLSGKFSFINGDLQSEPLTASWFNQPLNVDFSTKEGAKAYQ
                     VAVNLNGNWQPAKTGVLPEAVNEALSGSVAWDGKVGIDLPYHAGATYNVEMNGDLNNV
                     SSHLPSPLAKPAGEPLAVNVKVDGNLNSFELTGQAGADNHFNSRWLLGQKLTLDRAIW
                     AADSKTLPPLPEQSGVELNMPPMNGAEWLALFQKGAAESVGGAASFPQHITLRTPMLS
                     LGNQQWNNLSIVSQPTANGTLVEAQGREINATLAMRNNAPWLANIKYLYYNPSVAKTR
                     GDSTPSSPFPTTERINFRGWPDAQIRCTECWFWGQKFGRIDSDITISGDTLTLTNGLI
                     DTGFSRLTADGEWVNNPENERTSLKGKLRGQKIDAAAEFFGVTTPIRQSSFNVDYDLH
                     WRKAPWQPDEATLNGIIHTQLGKGEITEINTGHAGQLLRLLSVDALMRKLRFDFRDTF
                     GEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVAPEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQPRK
                     EKAQ"
     gene            complement(101529..102998)
                     /gene="rng"
                     /locus_tag="ACHY1N_000349"
     CDS             complement(101529..102998)
                     /gene="rng"
                     /locus_tag="ACHY1N_000349"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HFS4042707.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGEEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVGEAELASDAAYLKRVWTKVMERKKRPQTRYQLYGELALAQR
                     VLRDFADAELDRIRVDSRLTYEALLEFTSEYIPEMTSKLEHYTGRQPIFDLFDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSVNGFSALGLVEMTRKR
                     TRESIEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHSLAEVEIFVGKQVKVQIEPLYNQEQFDVVMM"
     gene            complement(102988..103581)
                     /gene="yhdE"
                     /locus_tag="ACHY1N_000350"
     CDS             complement(102988..103581)
                     /gene="yhdE"
                     /locus_tag="ACHY1N_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase YhdE"
                     /protein_id="HFS4042708.1"
                     /translation="MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQY
                     VVRLAREKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQ
                     VMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFV
                     RKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG"
     gene            complement(103590..104078)
                     /gene="mreD"
                     /locus_tag="ACHY1N_000351"
     CDS             complement(103590..104078)
                     /gene="mreD"
                     /locus_tag="ACHY1N_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFS4042709.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQ
                     QALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
                     VQ"
     gene            complement(104078..105181)
                     /gene="mreC"
                     /locus_tag="ACHY1N_000352"
     CDS             complement(104078..105181)
                     /gene="mreC"
                     /locus_tag="ACHY1N_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFS4042710.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDT
                     AVSPFYFVSNAPRELLDGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPVNTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQPTPQQPTTGNAATA
                     PAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ"
     gene            complement(105247..106290)
                     /gene="mreB"
                     /locus_tag="ACHY1N_000353"
     CDS             complement(105247..106290)
                     /gene="mreB"
                     /locus_tag="ACHY1N_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HFS4042711.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            complement(106595..108535)
                     /gene="csrD"
                     /locus_tag="ACHY1N_000354"
     CDS             complement(106595..108535)
                     /gene="csrD"
                     /locus_tag="ACHY1N_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HFS4042712.1"
                     /translation="MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQA
                     VATAIDTHLVSNDFSTLRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGSSD
                     LFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIIVMLFLAVRWLQR
                     QLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLREIQNAREQHSRLDT
                     LIRSYAAQDVKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHS
                     QVEEQFFTLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKEAESIAGQLIKAVDT
                     LPNNKMLDRDDMIHIGICAWRSGQDTEQVMEHAESATRNAGLQGGNSWAIYDDSLPEK
                     GRGNVRWRTLIEQMLSRGGPRLYQKPAVTREGQVHHRELMCRIFDGNEEVSSAEYMPM
                     VLQFGLSEEYDRLQISRLIPLLRYWPEENLAIQVTVESLIRPRFQRWLRDTLMQCEKS
                     QRKRIIIELAEADVGQHISRLQPVIRLVNALGVRVAVNQAGLTLVSTSWIKELNVELL
                     KLHPGLVRNIEKRTENQLLVQSLVEACSGTSTQVYATGVRSRSEWQTLIQRGVTGGQG
                     DFFASSQPLDTNVKKYSQRYSV"
     gene            108687..109661
                     /gene="yhdH"
                     /locus_tag="ACHY1N_000355"
     CDS             108687..109661
                     /gene="yhdH"
                     /locus_tag="ACHY1N_000355"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004024 - alcohol dehydrogenase (NAD+)
                     activity, zinc-dependent [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family oxidoreductase"
                     /protein_id="HFS4042713.1"
                     /translation="MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQEVLLTGWGVGENHWGGLAEQA
                     RVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVG
                     STAVALLHKLGYQVVAVSGRESTHEYLKSLGASRILPRDEFAESRPLEKQVWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRA
                     QAWQRLVADLPESFYTQAAKEISLSEAPNFAEAIINNQIQGRTLVKVN"
     gene            110639..111109
                     /gene="accB"
                     /locus_tag="ACHY1N_000356"
     CDS             110639..111109
                     /gene="accB"
                     /locus_tag="ACHY1N_000356"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFS4042714.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVM
                     QQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE"
     gene            111120..112469
                     /gene="accC"
                     /locus_tag="ACHY1N_000357"
     CDS             111120..112469
                     /gene="accC"
                     /locus_tag="ACHY1N_000357"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFS4042715.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKADTIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKA
                     SGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFNNDMVYMEKYLENPRHVEIQVLADG
                     QGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE
                     FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHA
                     VECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYG
                     ENRDVAIARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKLGLQEK"
     gene            112578..112820
                     /gene="yhdT"
                     /locus_tag="ACHY1N_000358"
     CDS             112578..112820
                     /gene="yhdT"
                     /locus_tag="ACHY1N_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HFS4042716.1"
                     /translation="MDTRFVQAHKEARWALGLTLLYLAVWLVAAYLPGVAPGFTGFPR
                     WFEMACILTPLLFIGLCWAMVKFIYRDIPLEDDDAA"
     gene            112810..114261
                     /gene="panF"
                     /locus_tag="ACHY1N_000359"
     CDS             112810..114261
                     /gene="panF"
                     /locus_tag="ACHY1N_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312157.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015081 - sodium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015233 - pantothenate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015887 - pantothenate transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0036376 - sodium ion export across plasma
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HFS4042717.1"
                     /translation="MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQ
                     TIDPQLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVIPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFH
                     PIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK"
     gene            114273..115154
                     /gene="prmA"
                     /locus_tag="ACHY1N_000360"
     CDS             114273..115154
                     /gene="prmA"
                     /locus_tag="ACHY1N_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFS4042718.1"
                     /translation="MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFAL
                     DPVVEKEEWCRITGRKN"
     gene            115483..116448
                     /gene="dusB"
                     /locus_tag="ACHY1N_000361"
     CDS             115483..116448
                     /gene="dusB"
                     /locus_tag="ACHY1N_000361"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFS4042719.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGY
                     RIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            116474..116770
                     /gene="fis"
                     /locus_tag="ACHY1N_000362"
     CDS             116474..116770
                     /gene="fis"
                     /locus_tag="ACHY1N_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HFS4042720.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            116856..117740
                     /gene="yhdJ"
                     /locus_tag="ACHY1N_000363"
     CDS             116856..117740
                     /gene="yhdJ"
                     /locus_tag="ACHY1N_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417728.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HFS4042721.1"
                     /translation="MRTGCEPTRFGNEAKTIIHGDALAELKKIPAESVDLIFADPPYN
                     IGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLF
                     TIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALI
                     DYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIV
                     LDPFAGSFTTGAVAVSSGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTG
                     NLSKRSRLSEVDPDLIAK"
     gene            117824..118003
                     /gene="yhdU"
                     /locus_tag="ACHY1N_000364"
     CDS             117824..118003
                     /gene="yhdU"
                     /locus_tag="ACHY1N_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 family protein"
                     /protein_id="HFS4042722.1"
                     /translation="MIRKYWWLVVFAVFVFLFDTLLMQWIELLATETDKCRNMNSVNP
                     LKLVNCDELNFQDRI"
     gene            complement(118006..118668)
                     /gene="acrS"
                     /locus_tag="ACHY1N_000365"
     CDS             complement(118006..118668)
                     /gene="acrS"
                     /locus_tag="ACHY1N_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrS"
                     /protein_id="HFS4042723.1"
                     /translation="MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVT
                     RGAIYWHFENKTQLFNEMWLQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAK
                     IPRQQALLKILYHKCEFNDEMLAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLD
                     VVMIIINGAFSGIVQNWLMNMAGYDLYKQAPALVDNVLRMFMPDENITKLIHQTNELS
                     VM"
     gene            119067..120224
                     /gene="acrE"
                     /locus_tag="ACHY1N_000366"
     CDS             119067..120224
                     /gene="acrE"
                     /locus_tag="ACHY1N_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrE"
                     /protein_id="HFS4042724.1"
                     /translation="MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIV
                     KTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQA
                     NYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
                     ATVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQS
                     SNDFMRLKQSVEQGNLHKENATSNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLR
                     AVFPNPQHTLLPGMFVRARIDEGVQPDAILIPQQGVSRTPRGDATVLIVNDKSQVEAR
                     PVVASQAIGDKWLISEGLKSGDQVIVSGLQKARPGEQVKATTDTPADTASK"
     gene            120236..123340
                     /gene="acrF"
                     /locus_tag="ACHY1N_000367"
     CDS             120236..123340
                     /gene="acrF"
                     /locus_tag="ACHY1N_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit AcrF"
                     /protein_id="HFS4042725.1"
                     /translation="MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVS
                     VSANYPGADAQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDI
                     AQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPDTTQDDISDYVAS
                     NVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ
                     LGGTPALPGQQLNASIIAQTRLKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYN
                     VIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQ
                     LSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLS
                     AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK
                     GGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEE
                     DQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAG
                     MAFVSLKPWEERNGDENSAEAVIHRAKMEFGKIRDGFVIPFNMPAIVELGTATGFDFE
                     LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGV
                     SLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMV
                     PFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGY
                     DWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLA
                     ATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLR
                     PILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR
                     CFKG"
     gene            123593..123814
                     /locus_tag="ACHY1N_000368"
     CDS             123593..123814
                     /locus_tag="ACHY1N_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4042726.1"
                     /translation="MKRLIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
     gene            124245..125270
                     /locus_tag="ACHY1N_000369"
     CDS             124245..125270
                     /locus_tag="ACHY1N_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4042727.1"
                     /translation="MKKMMIATLAAASVLLAVANQAHAGATLDAVQKKGFVQCGISDG
                     LPGFSYADADGKFSGIDVDVCRGVAAAVFGDDTKVKYTPLTAKERFTALQSGEVDLLS
                     RNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELN
                     VADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPAEWIVL
                     PEVISKEPLGPVVRRGDDEWFSIVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAH
                     LLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGI
                     QYAPPVR"
     gene            125338..126519
                     /gene="yhdX"
                     /locus_tag="ACHY1N_000370"
     CDS             125338..126519
                     /gene="yhdX"
                     /locus_tag="ACHY1N_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4042728.1"
                     /translation="MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTV
                     TNLNNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYGRVFIVGLLNTLLVSALCIVFA
                     SVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
                     FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWP
                     IAAVLIIGLPLLAQWLFGAALHWDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFI
                     AEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSS
                     LAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVE
                     R"
     gene            126529..127632
                     /gene="yhdY"
                     /locus_tag="ACHY1N_000371"
     CDS             126529..127632
                     /gene="yhdY"
                     /locus_tag="ACHY1N_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4042729.1"
                     /translation="MTKVLLSQPSRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWL
                     MWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINL
                     ALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLIVWWLMYGGFFGLERVETRQWGGLT
                     LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVML
                     PLFMAEGTNIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQ
                     GLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPTWLGMSTEG
                     YVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH"
     gene            127640..128398
                     /gene="yhdZ"
                     /locus_tag="ACHY1N_000372"
     CDS             127640..128398
                     /gene="yhdZ"
                     /locus_tag="ACHY1N_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4042730.1"
                     /translation="MSQILLQPANAMITLENVNKWYGQFHVLKNINLTVQPGERIVLC
                     GPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPH
                     LTVLQNCTLAPIWVRKMPKKEAEALAMHYLERVRIAEHAHKFPGQISGGQQQRVAIAR
                     SLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVI
                     FMDRGEIVEQAAPDEFFTHPKSERTRAFLSQVIH"
     gene            complement(128630..128745)
                     /gene="rrf"
                     /locus_tag="ACHY1N_000373"
     rRNA            complement(128630..128745)
                     /gene="rrf"
                     /locus_tag="ACHY1N_000373"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(128785..128860)
                     /locus_tag="ACHY1N_000374"
     tRNA            complement(128785..128860)
                     /locus_tag="ACHY1N_000374"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(128825..128827),aa:Thr,seq:ggt)
     gene            complement(128875..128990)
                     /gene="rrf"
                     /locus_tag="ACHY1N_000375"
     rRNA            complement(128875..128990)
                     /gene="rrf"
                     /locus_tag="ACHY1N_000375"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        31663 a        34251 c        32143 g        31014 t
ORIGIN      
        1 ggttataaat gaataaagtt acaaaaacag ctattgtggg cttacttgcg cttttcgcag
       61 gtaatgccgc tgcaaccgat ggtgaaatag tttttgatgg cgagatttta aaatccgctt
      121 gtgaaatcaa tgactctgat aagaaaattg aagttgctct tggtcactat aatgccgaac
      181 agtttcgttc tgttggcgat cgtagcccaa aaattccatt cactattcct ttagttaact
      241 gcccagtgac tgggtgggag cacgataacg gcaacgttga agcgtctttc cgtttatggc
      301 tggaaacgcg ggataatggc accgtcccta acttccctaa tctggcaaaa gtgggctctt
      361 ttgctggcac agcggcaaca ggtgtgggta tccgtattga cgatgcggaa agcggaaacc
      421 ttatgccact gaatgctatg gggaatgata acacggttta tcagatccca gcggactcca
      481 atggtattgt caatgttgac ctcatcgctt actacgtatc aaccgttgaa gcatcagaaa
      541 tcaccccagg ggaagcagac gctgtcgtta acgtaacgct ggattaccgt taatacgtta
      601 cggcgttatc tgacctttca gataacgccc ttttccttcc tctttctcgt tgtatcaggt
      661 tgaaaaataa ctatgtcaaa acgaacattc gcggtgataa taaccttgtt gtgtagcttc
      721 tgtatcggcc aggcgcttgc agggggtatc gttttacagc gaacgcgagt gatctatgat
      781 gccagccgca aagaggctgc gttacctgtc gcaaacaaag gcgcagaaac gccttattta
      841 ctgcaatcat gggtagataa tatagatggt acaagccgtg ccccatttat tataacccca
      901 ccgctatttc gtcttgaagc tggcgatgac tcatcactgc gaattattaa aacagctgat
      961 aacctgcctg aaaataaaga gtcgctgttc tacattaatg ttcgtgccat tccagcaaag
     1021 aaaaaatcag atgatgttaa tgctaacgag ttgacgctgg tatttaaaac acggatcaaa
     1081 atgttttatc gccccgcaca cctgaaggga cgggtaaacg atgcgtggac atcactggaa
     1141 tttaaacgta gtgaccattc actcaatata tataacccaa ctgaatatta cgtcgtattt
     1201 gccggactgg cagtcgataa aaccgatctc acaagcaaaa ttgaatatat cgcgcccgga
     1261 gaacataaac agttaccact tcctgcatct ggcggaaaga acgtgaaatg ggctgcaatc
     1321 aatgattatg gcggcagttc cgggacagaa actcgtccac tgcaataaca aatataaaaa
     1381 acacaggtca tcagggaatg ccacaacgac accaccaggg acataaacgc acaccgaaac
     1441 agttggcgct catcatcaaa cgctgtttgc cgatggtgct cactggcagc ggcatgcttt
     1501 gcactaccgc taacgccgaa gagtattatt tcgaccccat tatgctggaa actacaaaaa
     1561 gtggtatgca aacaactgat ctgtcacgtt tttcaaaaaa atacgcacaa ctaccaggaa
     1621 cttatcaggt tgatatctgg ctgaataaaa agaaggtttc acagaaaaaa attacattta
     1681 ccgccaatgc agagcaactt ctgcagccac agtttacggt agaacaacta cgtgagctgg
     1741 gtattaaggt ggatgaaatc ccggcgctgg ctgaaaaaga tgacgatagc gtgatcaact
     1801 cgcttgaaca aatcattccc ggtacagctg ctgaatttga tttcaatcat cagcgactta
     1861 atttgagcat tccccaaatt gcactgtacc gtgatgcaag aggttacgtc tccccttctc
     1921 gttgggacga tggtatacca acgctgttta ccaactactc gtttacaggt tctgataacc
     1981 gttaccgcca gggcaatcgt agccaacgac agtacctgaa tatgcaaaat ggtgctaatt
     2041 ttggcccctg gcgattacgt aactattcta cgtggacacg caacgatcag gcgtcaagct
     2101 ggaacactat cagtagttat ttacaacgtg atatcaaggc gttgaagtct cagttgcttc
     2161 tgggagaaag cgccaccagc ggcagtattt tttccagcta cacctttact ggcgtgcaac
     2221 tcgcttccga cgataatatg ttgccaaaca gccagcgcgg atttgcccca acggtacgcg
     2281 gtatcgcaaa cagtagtgca atcgtgacta tcaggcaaaa tggttatgtg atctatcaaa
     2341 gcaacgtgcc agcgggtgcc tttgaaatta acgatctcta cccctcttcc aacagcggcg
     2401 atttagaagt cacgattgaa gaaagtgacg gtacgcaacg tcgctttatc cagccttatt
     2461 cttcattacc catgatgcag cgacctgggc atctaaaata tagcgcgacc gctggacgct
     2521 atcgcgctga tgcaaacagt gatagcaagg aacccgaatt tgctgaagcc acggcaatat
     2581 atggtttgaa taatactttt acgctgtatg gcggcctgct cggttctgaa gattattatg
     2641 cgctggggat cggtatcggc ggcacacttg gcgcactggg cgcgttgtcg atggatatca
     2701 acagagctga cacccaattc gataaccagc actcttttca tggctatcaa tggcgtacgc
     2761 agtacatcaa agatatcccg gaaaccaaca ccaatatcgc tgtcagctac tatcgctata
     2821 ccaacgatgg ctattttagt tttaatgaag ccaatacccg taattggaac tataacagtc
     2881 gccaaaaaag tgaaattcaa ttcaacatca gccagacaat atttgatggg gtaagtctgt
     2941 atgcctccgg ttcgcagcaa gactattggg gcaataacga gaaaaacagg aatatctctg
     3001 ttggggtttc cggtcagcaa tggggaattg gttacagcct gaattatcaa tacagtcgct
     3061 acacggatca aaataatgac cgcgcactct atttgaatct cagtattccg ttagaacgct
     3121 ggttaccgcg tagccgggtt tcctatcaga tgaccagcca gaaagatcgc ccaacccaac
     3181 atgaaatgcg tcttgatggc tcactgctgg atgatggtcg cctgagctat agcctggaac
     3241 aaagtctgga tgacgataac aaccataaca gtagcctgaa cgccagttac cgttcacctt
     3301 atggcacctt cagtgccgga tacagctacg gtaatgacag cagccaatac aattacggcg
     3361 ttaccggcgg cgtggttatc catcctcatg gcgtgacgct ctcgcaatat ctgggcaacg
     3421 cttttgcgct tatcgatgct aatggggctt ctggcgtgag gatacaaaac tatccgggga
     3481 ttgctactga tccctttggc tatgcagtgg ttccttatct cacgacttac caggaaaacc
     3541 gtctctcggt agatactacg cagctgcccg ataacgtcga tcttgagcaa acaacacagt
     3601 ttgtggtgcc caacagaggt gcaatggtag cggcgcgttt caacgccaat atcggttatc
     3661 gcgtacttgt tacagtcagc gatcgcaacg gtaaaccgtt gccctttggc gctcttgcca
     3721 gcaacgatga gacggggcaa caaagtatcg tcgatgaggg cggcatacta tatctctctg
     3781 ggatatcgag taaatcacaa agctggactg tacgctgggg aaatcaggca gatcaacaat
     3841 gtcagtttgc ttttagtaca ccggattcag aaccaacaac ctctgtatta caaggcacgg
     3901 cgcagtgcca ttaaggataa aaaaatgaaa agagcgcctc ttataacagg acttttgttg
     3961 atatccacat cctgcgctta tgcctcctca ggagggtgtg gagctgacag cactagcggt
     4021 gcgacaaatt acagcagtgt ggttgatgat gttacggtga accagacaga taacgtgaca
     4081 ggacgggagt ttacctctgc cacgctaagt agcactaact ggcaatacgc ctgtacctgc
     4141 tctgcgggta aggcagttaa acttgtctat atggtcagcc ctgtacttac caccactgga
     4201 catcaagcag gatattacaa actcaatgat agtctggata ttaaaaccac attacaggcg
     4261 aatgacattc caggactcgt gactgaccag accgtttctg ttaacacccg attcacacag
     4321 ataaaaagca acaccgtata ttctgctgca acccaaacgg gtgtttgcca gggtgacacg
     4381 tctcgttatg gacccgttaa tattggtgca aataccacct ttaccctgta tgtcaccaag
     4441 ccatttctcg gctcgatgac cattccgaaa acggatattg ccgtcattaa aggcgcatgg
     4501 gtcgatggaa tgggaagccc gtctacaggt gacttccatg atttagtcaa gttatcgatt
     4561 cagggaaatc tcaccgcccc acagtcgtgc aaaattaatc agggcgatgt tattaaggtt
     4621 aattttggat tcatcaatgg tcagaagttt accacccgca atgccatgcc agatggtttt
     4681 actccagtag actttgatat cacttatgac tgtggtgata cttcaaagat taaaaactcg
     4741 ttgcaaatgc gcatcgacgg tacaactggg gtagtagacc agtacaacct ggtcgccaga
     4801 cgaagaagtt cagacaatgc gcccgatgtc ggtattcgta ttgaaaatct cggcggcgga
     4861 gttgcaaata ttccttttca gaacggtatc cttcccgttg atccttccgg gcatggcacc
     4921 atcaacatgc gcgcctggcc agttaatctg gtcggtggtg agctggaaac aggaaaattt
     4981 cagggcaccg ccaccattac cgtcatcgtg cggtaaaaga agacgttgcg ttttgattaa
     5041 cgcaacgctt cggcactctt acccctgctg ctccagcgca tacttataca gcgcattttt
     5101 cttcacgccg tgaatttctg ccgccagcgc cgccgctttt ttcaacggca gttctgcctg
     5161 tagcagcgcc agcgtgcgca gggcatcggc gggtaagtct tcttcctgtg ctttatgacc
     5221 ttcgataatc agcaccattt cgcctttgcg acggttttca tcttctttta cccacgccag
     5281 cagctcgcca acgggcgcgc cgtgaatggt ttcccaggtt ttggtcagct cacgcgccag
     5341 aaccacgtag cgggattcgc ctaataccgc aacgatatct tccaggctat ctaacagacg
     5401 gtgggtggat tcataaaaaa tcagcgtgcg cggctccgct tcaatggctt ttagcgcatc
     5461 acggcggcct tttgatttgg caggtaaaaa gccttcgtaa cagaaacggt cagagggtaa
     5521 acccgcggcg cttaacgcag tgatagcagc acacggcccg ggtagcggca ccacgcaaat
     5581 ccccgcttca cggcaggtac gcaccagatg gtagccagga tcgttaatta gcggcgttcc
     5641 ggcatcggaa accagcgcaa tgttctgccc ttcttgcagc ttcgccagca gcgtttcggc
     5701 tttttgttgt tcgttatggt cgtgcagcgc aaacaaccgg gcattaatcc caaaatgttg
     5761 cagcaataaa ccggtgtgac gagtatcctc ggcggcaatc agatcaacgg cctgtaatac
     5821 ctctaacgca cgctgggtga tatccgccag attgccgatt ggcgtcggta caatgtaaag
     5881 ctggccctga gaattatccg ccgattggtg ttgtttcatt gtgtcgtccg tattgccgat
     5941 ttaatattga gcattgcgta aaaaaatatc actggataca ttatggtacc ctcaacattt
     6001 tctcgtttga aagccgcgcg ttgtctgcct gttgttctgg cagccctgat tttcgccggt
     6061 tgtggcaccc atactcccga tcagtccact gcttatatgc agggcacgac gcaggctgat
     6121 tctgcctttt atcttcagca gatgcagcaa agctctgatg ataccaggat caactggcaa
     6181 ttactcgcca ttcgtgcact ggtgaaagaa ggtaaaaccg ggcaggcggt tgagttgttt
     6241 aaccaactac cgcaagaact gaacgattct cagcgtcgcg agaaaacact gctggcggta
     6301 gagattaaac tggcgcagaa agattttgct ggcgcgcaaa acttgctggc gaaaatcaca
     6361 cctgccgatt tagaacaaaa ccagcaagcg cgttactggc aggcaaaaat cgatgccagc
     6421 caggggcgtc cttccattga tttactgcgc gcgttaattg ctcaggaacc gctgctcggc
     6481 gcgaaagaaa aacagcagaa tattgatgcc acctggcagg cgctctcctc catgactcag
     6541 gaacaggcga atacgctggt gatcaacgcc gacgaaaata ttctgcaagg ctggctggat
     6601 ctgcagcgcg tctggtttga taaccgtaac gatcccgaca tgatgaaagc cgggatcgcc
     6661 gactggcaaa aacgttatcc gaacaatccg ggcgcgaaaa tgctgccaac gcagttggtt
     6721 aacgtaaaag cgtttaaacc agcctcgacc aacaaaatcg ccctgctgtt gccgctgaat
     6781 ggccaggcag cggtatttgg tcgcactatt cagcaaggct ttgaagcggc gaaaaatatc
     6841 ggcactcagc cagtggcggc tcaggtagct gccgcacctg ccgcagacgt agctgaacaa
     6901 cctcagccgc aaaccgtgga tggcgttgcc agcccggcac aagcctcggt tagcgatctg
     6961 accggtgaac agcctgcggc acagccagcg cctgtaagca ccccggcagc aaccaccaca
     7021 gcggtaagcg cgccagcgaa tccatccgca gaactgaaaa tctacgatac ctcatcacaa
     7081 ccacttagcc agatcttaag ccaggttcag caggatggcg cgagtattgt ggttggtccg
     7141 ttgctgaaaa ataacgttga agagttgctt aagagcaaca ccccgctgaa cgtgctggca
     7201 ctgaaccagc cggagaatat cgaaaaccgc gtcaatattt gttacttcgc gctttcaccg
     7261 gaagacgaag cgcgcgatgc agcgcgtcat attcgtgacc agggtaaaca agcgccgctg
     7321 gtgctgatcc cacgcagttc attgggcgat cgcgtagcca atgcgtttgc gcaggagtgg
     7381 cagaaactgg gcggcggcac cgttctgcaa caaaaatttg gttccaccag cgaattacgc
     7441 gcgggtgtta acggcggttc tggtatcgct ttaacgggta ccccgattac tcccagagcg
     7501 acaaccgatg accagttcac caataatggc ggtcgtgtcg atgcggtgta cattgtggca
     7561 acgccgggtg aaatcgcttt tatcaaaccg atgatcgcca tgcgtaacgg tagccagagc
     7621 ggtgcaacgc tgtacgccag ctcccgcagt gcgcaaggga ccgctggccc ggatttccga
     7681 ctggagatgg aaggcttgca gtacagcgaa atcccgatgc tggcaggcgg taatctaccg
     7741 ttaatgcagc aggcactcag cgcggtgaat aacgattatt cactggctcg catgtatgcg
     7801 atgggcgtcg atgcctggtc gctggcaaat catttctcac aaatgcgcca ggttcagggt
     7861 tttgaaatca acggtaatac cggaagcctg acggcaaacc cggattgcgt gattaacagg
     7921 aagttatcat ggctacagta ccaacaaggt caggtagtcc ccgccagtta accaccaaac
     7981 agaccggcga tgcgtgggaa gtacaagcgc gtcgctggct ggaaggcaaa ggactgcgat
     8041 ttgtcgccgc taacgtgaac gagcgtggcg gcgagatcga tctgataatg cgtgaaggcc
     8101 ggaccaccgt ttttgtcgag gtacgctatc gccgctctgc gctttatggc ggcgcggcag
     8161 ccagtgtgac ccgcagcaaa caacacaaat tattacagac tgcccgcttg tggctcgcgc
     8221 gtcataatgg gagttttgat actgtggatt gccggttcga tgtggtagcc ttcaccggga
     8281 atgaggttga gtggattaag gatgccttta atgaccactc ataattaagg tttaaggatt
     8341 agcgtgcaag aaagaattaa agcttgcttc actgaaagca ttcaaactca aattgcggcg
     8401 gcagaggcgc ttccggatgc catctcccgt gcagccatga cgctggttca gtctctgctc
     8461 aatggcaaca aaatcctctg ttgtggtaat ggaacttccg ctgccaatgc acagcatttt
     8521 gctgccagca tgatcaaccg tttcgaaacg gagcggccca gcttacctgc cattgcacta
     8581 aatactgata atgttgtctt aacggcgatt gccaacgatc gcttacatga tgaagtgtat
     8641 gcaaaacagg tgcgggcgct gggtcatgcg ggagatgtat tgttagccat ttccacccgt
     8701 ggcaacagcc gcgatattgt aaaagcggta gaagctgccg ttacgcgtga tatgactatt
     8761 gtggcattga ccggctatga cggcggcgaa cttgcaggtt tgttagggcc acaagatgtg
     8821 gagatccgca ttccttcgca tcgtagtgct cgcattcagg aaatgcatat gctgacggta
     8881 aattgcctgt gcgatctgat cgataacacg cttttccctc accaggatgt ttaaggagaa
     8941 tacatgaagg cattatcgcc aatcgcagtc cttatttccg cgctgctgtt gcaaggttgt
     9001 gttgccgctg ccgtagtggg taccgctgct gtgggtacca aagccgcaac tgacccacgc
     9061 agtgtcggca cccaggtgga cgatggtacc ctggaagtgc gcgtgaacag cgcattgtcg
     9121 aaagacgaac agattaagaa agaagcccgt attaatgtca cggcgtatca gggcaaagtg
     9181 ctgctggttg ggcagtcacc aaacgctgaa ctttcggctc gcgccaaaca gattgctatg
     9241 ggcgtagacg gtgccaacga agtgtataac gagattcgtc agggccagcc gattggtctg
     9301 ggcgaagcgt ctaacgatac gtggatcacc accaaagtgc gttcgcagct cttaaccagc
     9361 gacctggtga aatcgtccaa cgtgaaagtg accaccgaaa acggtgaagt gttcctgatg
     9421 gggctggtga ctgaacgtga agcgaaagcg gcggcagata ttgccagccg ggtgagcggc
     9481 gtaaagcggg taaccacagc gtttacgttt attaaatagc agccccttgt aatgcctgat
     9541 gcgacgcttg ccgcgtctta tcaggcctac aacgatgcaa accgtaggtc ggataaggcg
     9601 tttacgccgc atccgacatg ttttccctca aatcagaaca acagcgccag cccgccgaca
     9661 atcacaccag acactgccac catcgcccct gtcagccata aggctttcgc tgggaacgct
     9721 ttgcgcagca taatcagtga cggcaaactc accgccggga gcgtcatcaa caatgccagc
     9781 gccggagcag ttcccatacc tgccagcatc atcgtttgta caatcggaat ttctgctgcc
     9841 gtgggaatga caaacaagca tcctgctacc gccatcgcca tcacccacat caggctgtta
     9901 tcgacagcac catcggcatg ggggaataac cagacgcgag cggcacccaa caccagtact
     9961 gcaaggatgt aaaccgggat cgtactccag aaaagcgtcc atagcgccct gccccagcgg
    10021 ctaaaaaaac cgccctgtgc ttccggtatg tcaatttcga ccggtgcctg cgtttgcggt
    10081 gtttcacgca cccatttttg caccagcgtc gcaatcagca acaccatcac cagcccggcc
    10141 accagacgaa tcgccgcaaa accccagccg aggacaaacc ccataaacac cagcgtcgcc
    10201 gggtttaaca ccggattgcc catccagaat gccagcgcac cgcccatcga cacctgttgg
    10261 cgacgcattc ccgccgcgac cggagccgca cagcaggtac acatcatgcc cggcagcgaa
    10321 aacagcgttc ccagcagcgt gccgcgaaag cgcgattgcc caagcgtacg caacaaccag
    10381 tcacgcggga tcagcacctg aatcaacgaa ccgaggatca cccccagcac tgccgctttc
    10441 cataccgcga ggaaatagat catcgcgtaa tccaacgccg cctgccacgg attagcatcc
    10501 gcctgcgcaa ggatagattt accgatactg tgggtttcgg cagcagtaaa cgctttgccg
    10561 tagtaaggtt gccatttcac ataccagaga ccggcaatga caacgagaaa gaaaagcgcg
    10621 ggtttccacc actgaatggg cgttgccgcc tgagatgaag actgaccagt catagcattc
    10681 cccaggaata agttatgata attgagcgcg tgaatattac gctcactatc aattcttggg
    10741 aataattatt cagctctttt gcgtaattct gaagagctta aaatcgtcac accttcatgc
    10801 ccgggccgca tcgcctctgc cagcatgacc cgcgccacgt ctctcgcatc aatggatttc
    10861 cagttaccgg gtaataaacg gaacagcggc gcaaaaagcg tttcgttcat ccgctgtttg
    10921 ctacgatcgc ccagtaacat cgacgggcga gcaatggtca atttcggcca gttctgggcg
    10981 attaatgctt cttccatctc ccctttgacg cggttataga aaaacggcga gtgggcattg
    11041 gcacccatag cactgaccac cagcatatgc tgcgcgccca gtcgccgccc ggttaatgcg
    11101 gtatccacta ccagcgtgta atcggcatga ataaacgcct ctttgctccc cgcttctcgc
    11161 cgcgtggtgc cgagacaaca aaacacaatg tcgatgggat cggtgacctg cgccagcgcg
    11221 tcagtcagtt gcggatcatg gggattaaac accccgggca tatcgcccaa cggacgtcgc
    11281 gtcggcgcgg ctatggcgtt aactttcggt tcgttaatca acatccgcag caggtgaccg
    11341 cccaccagcc ccgttgcgcc tgtaatcagt acctgactca tcttcgctcc tttacagaat
    11401 tgtctgcctt gcgctccacg gctcatgcac caggcttaat agaccatgag gtaattatcc
    11461 ccgattgtgg gaaattcgcc tcatccaatg caacaacgcg gaggaagcat gagtaagaaa
    11521 attgccgttt taatcactga tgaatttgaa gattcagaat ttacttcacc cgcagacgag
    11581 ttccgtaaag ccggacacga agtgattacc attgaaaaac aagcgggtaa aacggtgaaa
    11641 ggcaaaaaag gagaagccag cgtgaccatc gataaatcca tcgatgaagt gacgccagcg
    11701 gagtttgatg ccctgctgct accgggcggc cattcaccgg attatctgcg tggcgacaac
    11761 cgttttgtca cctttacccg tgattttgtg aatagcggca aacctgtttt cgccatctgt
    11821 cacggtccgc agctgctgat cagcgccgat gtgattcggg ggcgcaaact gaccgcggtt
    11881 aaaccgatca ttattgatgt taaaaacgcg ggcgcggaat tttacgatca ggaagtcgtg
    11941 gtcgataaag atcagctggt taccagccgg acaccggacg atctgccagc gtttaaccgc
    12001 gaggcgttac gcctgctcgg tgcctgagcc gcgtagccaa atcatttttt taccaaagcc
    12061 cagcgtgttg tcggtgaatt tgatttcatc gagccggatt tcccacaccg gggccgacag
    12121 cattctggca accggaaagc gacgattgta cgccttgcgc gcgaggtcgc tttcctcacc
    12181 ttccagcctg cggatctcac ctttaaactg cacgccgcga attaacgcta ccgttttcgg
    12241 ctgaccgttt accgttccgg caaccgcagc ctgcggccca ctcatctgcg cgtggcgcgt
    12301 tttttcttcc gtcaaaatgt agaaggcgac tttctgcgca tcaaacagat aaaaagcatt
    12361 agcgcaccag agttcccctt cctgctgcac acaccaggtg acaacatgtt gttttgccaa
    12421 ccaacggctg atggtgatga gtgtttccat tgctgttctc ttttatactg tgggcctgac
    12481 cttaacatgc gacgcagacg atgacaccct ggtttcttta cttgatccgt accgccgaca
    12541 ataagcttta taccgggatc accacggatg tcgaacgccg ctatcagcag caccaaagcg
    12601 gcaaaggggc gaaagcactg cgcgggaaag gagaactgac gctggcgttt tctgcgccag
    12661 tgggcgatcg ttcgctggcg ttacgggcgg aatatcgcgt taagcaactg accaaacggc
    12721 aaaaagagcg tctggtagcg gaaagcgcag ggtttgcaga gctgttaagc agtctgcaaa
    12781 ccccggagat taaaagcgat tgaaatgctc gtgatactca accagaccag ttacgccatt
    12841 caacgcgtca tccgctaaac gatgtacctg gaaggcgctt tcagtgcctg gccagcggca
    12901 acgcaggtcg tgatgtgccg ccagttcaaa gccaaaacgg ctgtacagcg ccggatcgcc
    12961 cagcgtcacc actgcggcat agccgaactc attaagcgaa tcgagtcctt catagaccag
    13021 ttggcgtgcc agcccctgtc cacggtattt ttcatcaacc gccaacggtg ccatgccgac
    13081 ccattgcagg tcttcgccct gcacatcaac cggactaaat gccacatagc caatgacctg
    13141 accttcgtca tctgtcgcca ccagccccag cgtcagaaag ccatcttcac gcagatcgtg
    13201 aaccagcttc gcttccgcat cactttcgaa tgagcgacgt agcagggcat caatacccgg
    13261 cgcatcaatg ggaatttcta ctcgaattag catggttcac ctaccgatgt ctgtttggtt
    13321 tcaggcgcgg ttttcattcc cgcctcaaca aaatccgcca gttgcagcag catcatgcgt
    13381 aaggctttcg gcatttgctc cagttcaatg gcgtccatca ggtttttcac atacagcccc
    13441 agctccgtat cgccttcaat caccagccga cgctggaaga agagcgtatc cggatcttgt
    13501 ttacgcgccg caatcatcag cagatcgctg gcgtcggcac taaaactcac atcagcttgc
    13561 gcgttctggc tgaccaccag tttgccattc accaccgagg taaaccattg caggtcaata
    13621 tcacgcacat gaatacttaa ccagcggcct tcaagaaact ccagctcgcc atcatccagc
    13681 gcctgacgga attgccagct taagacctgc tcaagaacct ggcgttttag cgcaaatggc
    13741 gtcagtttta ccggtacact caacagagat ggccccaaat gcacaatacg ggaacgcagt
    13801 ttatccaaca cgagttttac tccctgtttc aacaatcatc ctattttgcc atatcagaaa
    13861 aataacatag cggtataaat caacaattcc atatgaaatt gctgctacca ccaatacaac
    13921 tttaactgcc ttaaatcaaa aattgtcgca gcaaggttaa ctaaaatccc agttcgttaa
    13981 catttttgcg ttttgatagc gcaaccttca ggaaaaatta tggagctgct ctgccctgcc
    14041 ggaaatctcc cggcgcttaa ggcggccatc gaaaacggcg cagatgctgt ttatatcggg
    14101 ctaaaagatg ataccaatgc ccgtcacttc gccggcctta actttaccga gaaaaaattg
    14161 caggaagcgg tgagttttgt ccatcaacat cgccgcaaac ttcacatcgc gattaacact
    14221 tttgcgcatc cggacggtta cgcccgttgg cagcgtgccg tggatatggc ggcgcagctg
    14281 ggtgccgacg cgctgatcct cgccgacctc gccatgctag agtacgccgc cgagcgttac
    14341 ccgcatattg agcgtcatgt gtcagtgcag gcttcggcga ccaatgaaga ggcgattaac
    14401 ttttatcatc gccattttga cgttgctcgc gtggtgctgc cgcgcgtgtt gtcgattcat
    14461 caggtgaaac aactggcacg ggtcacacct gtaccactgg aagtctttgc tttcggcagc
    14521 ctgtgcatta tgtcggaagg tcgttgctat ctgtcgtcgt atctgacggg tgagtcgccc
    14581 aacaccgtag gcgcgtgttc tccggcccgt ttcgtgcgct ggcaacaaac gccgcagggg
    14641 ctggaatccc gcctgaacga agtgctgatc gaccgttatc aggacggcga aaacgcaggt
    14701 tatccgacgc tatgtaaagg gcgttatctg gtggacggcg agcgctatca cgcgctggaa
    14761 gaaccaacca gtctcaatac cctggaactg ctgccggagt taatggcggc gaatattgct
    14821 tcggtgaaaa ttgaaggccg ccagcgtagc ccggcgtatg tcagccaggt ggcgaaagtc
    14881 tggcgtcagg ctatcgaccg ttgtaaggcc gatccgcaaa acttcatacc gcaaagcgcg
    14941 tggatggaga cgctcgggtc gatgtccgaa ggcacgcaga ccacccttgg cgcgtatcac
    15001 cgtaaatggc agtgagaaga gcaatgaaat attccttagg gccagtgctg tggtactggc
    15061 caaaagagac gctggaagat ttttatcagc aggccgccac cagcagcgcc gacgtgattt
    15121 atcttggtga agcgatatgc agcaagcgcc gggcaaccaa agttggcgac tggctggaga
    15181 tggcaaaatc gctcgccgga agtggcaagc agattgtgct ctccacgctg gcgctggtgc
    15241 aggcatcctc tgaactgggc gaactgaaac gctatgttga gaacggtgag tttctgattg
    15301 aagccagcga tctcggcgtg gtgaatatgt gcgctgaacg caaactgccg ttcgtcgccg
    15361 ggcacgcgct gaactgctac aacgcggtga cgctgaaaat attgctcaaa cagggcatga
    15421 tgcgctggtg tatgccggtg gagctttccc gcgactggct ggtgaatctg cttaatcagt
    15481 gcgatgagct gggcattcgc aaccagtttg aagtggaagt cctgagctac ggtcatctac
    15541 cgctggccta ctccgcccgc tgctttaccg cgcgttcgga agaccgcccg aaagatgagt
    15601 gtgaaacctg ctgcattaag tatccgaacg ggcgcaacgt gctgtcgcag gaaaaccaac
    15661 aagtgtttgt actcaatggc attcagacca tgagcggcta cgtttacaac ctcggtaacg
    15721 agctggcatc catgcagggg ctggttgatg tggtccgcct gtcaccgcag ggtactgaca
    15781 ctttcgcgat gctcgacgcc ttccgcgcta atgaaaatgg cgctgcgcca ctaccgttga
    15841 cggcaaacag cgactgtaac ggctactggc ggcggctggc cgggctggag ctgcaagcct
    15901 aagtaaatat gctcgtcata cttcaagttg catgtgctgc atctgcattc gttcacccca
    15961 gtcacttact tatgtaagct cctggggatt cactctcttg tcgccttcct gcaactcgaa
    16021 ttatttagag cacagctcac tttgttaaca actttaacta ctctttaatg cagtattaaa
    16081 gattaatcgg taacaaagtg agctgttatg actgataaaa ccattgcgtt ttcgctactc
    16141 gatctggccc ccattcccga aggttcttca gcgcgagaag cattctccca ctctctcgat
    16201 ctcgcccgtc tggctgaaaa gcgcggctat catcgctact ggctggcaga acaccacaat
    16261 atgactggca ttgccagtgc tgccacgtcg gtattgattg gctatctggc ggcgaatacc
    16321 accacgctgc atctggggtc tggcggcgtg atgttgccta accactcacc gttggtcatt
    16381 gccgaacagt tcggcacgct caatacactc tatccggggc gaatcgattt ggggctgggt
    16441 cgtgcgccag gtagtgacca acggacaatg atggcgctgc gtcgccatat gagcggcgat
    16501 attgataatt tcccccgcga tgtcgcggag ctggtggact ggtttgacgc ccgcgatccc
    16561 aatccgcatg tgcgcccggt accaggctat ggcgagaaaa tccccgtgtg gttgttaggc
    16621 tccagccttt acagcgcgca actggcggcg cagcttggtc tgccgttcgc gtttgcctca
    16681 cacttcgcgc cggatatgtt gttccaggcg ctgcatcttt atcgcagcaa cttcaaaccg
    16741 tcggcacgac tggaaaaacc atacgcgatg gtgtgcatca atattatcgc cgccgatagc
    16801 aaccgcgacg ctgagtttct gtttacctca atgcagcaag cctttgtgaa gttgcgccgt
    16861 ggcgaaaccg ggcaactgcc gccaccgatt caaaatatgg atcagttctg gtcgccgtcc
    16921 gaacagtatg gtgtgcagca ggcgctgagt atgtcgttgg taggtgataa agcgaaagtg
    16981 cgtcatggct tgcagtcgat cctgcgcgaa accgacgccg atgagattat ggtcaacggg
    17041 cagattttcg accaccaggc gcggctgcat tcgtttgagc tggcgatgga tgttaaggaa
    17101 gagttgttgg gatagtgtgt cttaacgcgg gaagccttat ccgagctggc aacgctgtcc
    17161 tacgtagacc tgataagcga agcgcatcag gcattgtgta ggcagcagaa atgtcggata
    17221 aggcaccgct gattactgat acaccggcag taaattaaag ctcgataaaa tatggaccag
    17281 tgcgttgcca acgccaaaca ccagaatcag cgtaatcatc ggcttgccgc cccagacgcg
    17341 gaatttcggg ctgccaaagc gtttacgcga tgcgcgggct aacagcgccg gaacaattgc
    17401 cgcccagatg gtagctgcta aaccagcata accaatggcg tacaggaatc cgttcgggaa
    17461 cagtagacca cccacaacag gcggggcaaa ggtcagcaat gccgttttca agcgccccag
    17521 ggctgagtca tcgaaaccaa acagatctgc cagatagtca aacaaaccca gcgttacgcc
    17581 aaggaacgaa ctcgctaccg caaagtttga gaacacgacc agcagaaggt ccaggctacg
    17641 gctgttcagc acgccgctta atgcctgtac cagcacatca atattaccgc ccttctctgc
    17701 aataccgata aactccggac gcgggatgtt acccatcgtc gccagcaacc agatggtata
    17761 cagcgccagt gccatcagcg taccgtacac caggcatttc acgatggttt tcggatcttt
    17821 gccgtaatac ttcatcaggc ttggcacgtt accgtgataa ccaaacgacg ccaggcagaa
    17881 cggcaatgtc atcagcagat acggcgcata agatgcattg ctttctgcaa cgttgaacaa
    17941 tgtcgcaggc tgcacatgcc ccaacaggct gccaaaggtg aggaagaagg taatgacttt
    18001 cgcccccagc acaatcgccg tcatgcggct gacggcctta gtactcaacc acaccacaaa
    18061 cgctaccagc agtgcaaaac caaaacccgc cgcccgtgcc gggacgttta gcgacatctc
    18121 tgcgaaggtg tgatgcagaa ttgaaccact ggcagaaata taggcatagg tcaggatata
    18181 gagcacaaag gcaatggaaa taccgttgac cacgttccag cctttgccca gcaaatcttt
    18241 ggtgatggtg tcaaaactcg aaccgattcg gtaattcagg ttagcttcca gaatcatcaa
    18301 gccggaatgc agcatacaga accaggtaaa gatcagcgcc gccattgacc agaaaaacca
    18361 cgccccggac atgaccactg gcagagaaaa catccctgcg ccaataatgg tgccgccgat
    18421 aatcaccacg ccgccaagca gcgacggtga cgtttgggtg gtggttagtg ttgccatgag
    18481 ggcttctctc cagtgaaaaa tagtgcgact gcgttgttat gcattgcact gtaccagtac
    18541 acgagtacaa aagacagaaa aaaagccccg atggtaaaaa tcggggctgt atatattatt
    18601 ttacagattg tgttcgctgt tcagcgatga ttacgcatca ccaccgaaac gacgacgacc
    18661 ggtagagtca tcacgacgcg gagcgcggcc ttcacgacgt tcgccgctaa aacgacgacc
    18721 atcaccacgg ccaccttcac ggcgttcacc actgaagtta cgaccgcctt cacgacgttc
    18781 gccaccgaaa ccacgaccac cgccacgacg ctcaccgcca gtatgcggct gtgcatcgcc
    18841 cagtaactgc atgttcatcg gcttgttgag aatgcgagta cgcgtaaagt gttgcagcac
    18901 ttcacccggc atacctttcg gcagttcgat ggtggagtga gaagcaaaca gcttgatgtt
    18961 accaatgtaa cggctgctga tgtcgccttc gttagcaatc gcaccaacga tatgacgaac
    19021 ttcaacacca tcatcgcggc ccacttcaat gcggtacagc tgcatatcgc caacatcacg
    19081 acgttcacga cgcggacgat cttcacggtc accacgcggg ccacggtcgt tacgatcgcg
    19141 cggaccacgg tcatcacggt cacggaattc acgtttcgga cgcatcggcg catctggcgg
    19201 tacgatcaga gtacgttcac cctgtgccat tttcagcagt gccgcagcca gagtttcgag
    19261 atccagctct tcaccttctg cagtcggctg aattttgctc agcagtgcgc ggtattgatc
    19321 cagatcgctg ctttccagct gctgctgtac tttagcggcg aatttttcca gacggcgttt
    19381 gcccagcagt tctgcgttcg gcagttctac ttccggaata gtcagcttca tagtacgttc
    19441 aatgttgcgc agcagacgac gctcgcggtt ctcaacgaac agcagcgcgc ggccagcacg
    19501 acccgcacga ccggtacgac cgatacggtg aacgtaagac tcagaatcca tcgggatatc
    19561 gtagttaact accaggctga tacgctcaac gtccaggcca cgggctgcaa cgtcggtcgc
    19621 aatcaggatg tccagacgac catctttcag gcgttccagt gtctgttcac gaagcgcctg
    19681 gttcatgtca ccgttcagcg cggcgctgtt gtagccgtta cgctcaagag cttcagccac
    19741 ttccagagtc gcgtttttgg tacgaacgaa gataatcgcc gcatcaaaat cttccgcttc
    19801 caggaaacgt accagtgctt cgtttttgcg cataccccag acagtccagt agctctggct
    19861 gatgtcagga cgggtagtca cgctggactg aatgcgcact tcctgcggct ctttcataaa
    19921 gcggcgggta atgcgacgaa tcgcttccgg catggttgca gagaacagag cggtctgatg
    19981 accttccggg atctgcgcca taatggtttc aacgtcttcg atgaagccca tgcgcagcat
    20041 ttcgtcagct tcatccagaa ccagaccgct cagtttagag aggtccagag tgccacgttt
    20101 caggtggtcc agcagacggc ccggagtacc gacaacgatc tgcggcccct gacgcagggc
    20161 gcgtaattgc acgtcataac gctggccgcc gtacagagca accacattta cgccgcgcat
    20221 gtgtttagag aaatccgtca ttgcttcagc aacctgtacc gccagttcgc gggtcggtgc
    20281 cagcaccaga atctgtggtg ctttcagctc aggatcaaga ttctgcagca gaggtaaaga
    20341 gaatgctgca gtttttccgc tccccgtctg ggccataccc agaacgtcgc ggccattcag
    20401 cagatgtgga atacactctg cctgaattgg agatggtttt tcgtaaccca gatcgttaag
    20461 ggcttcaagg ataggagcct tcaggcccag atctgcaaaa gtggtttcga attcagccat
    20521 gtagtacgtg tgcctcaaaa ttaatggcgg ccagtctaca taactcatca tgaaattgat
    20581 cagcaatttt cattgaaaag tgtgaaccgg ctcaaagtag gtgtattaac gaacaacaac
    20641 gccctcaccc gttaaggtga tggcaatcaa aaaagattac gggctgatgt gtacgtcagc
    20701 tattgctggt ccgattctgc caggtcatct tggtcctggc ccaggagcga taattccaac
    20761 aatgcgtatc ggtgctcaac aaagttatga acgttgttgg caaccgccag tttgaacagt
    20821 gccgtggcgc tgtccaaatc ccccagactt aggtagtact tacctaaata gaagttggtt
    20881 tcactgagat gctcagcgag cgaggtgtta tccgttgcgt ccgccttgag cctttccatt
    20941 aacgtttgtt cgctaatgtt gcccaggtag aactcgacaa tgttccatcc ccactgttcc
    21001 ttatccgatt tttcgaagtg ctgtttcaac acttctttag cctgcttctc atcgagcttc
    21061 tgctcggcga gataaagcca cagactacgg aaaggatcat tgggatcgtc ttgataaaac
    21121 gccagcagat catcttgcgc taacttgtca cgaccgccgt aatataatgc gatcccgcga
    21181 ttcaagtgcg cgtagttgta agttggatca agctcaagta cagaatcaaa cgcttcatag
    21241 gcagcatcaa aattgcctgc ctgcgttaaa tatatgccta agtaattgaa tacttcaggc
    21301 atatccggtc ggattgccag cgcttgcgaa aaatcgttac gcgctaatgc cctcagaccg
    21361 agactatcat acaacactcc gcgctcatat aaaagctgtg cgcgttcgtc atcggttaaa
    21421 gcccgactgg caaggatttg ttccatacgt gccagaatca cttcctgctg taaagtcggt
    21481 tgcaatggta ccgcgaggac ttcactttta cgccaggaag tattactgca tcctgcaagc
    21541 gtaagtgctg tcgcaacgaa acaccagcgc aaaaaaggct tcatttccca ctcccgaaga
    21601 ccacggttga atgaacgtcc tgttcccggt tgctaacaag gcgtcctgcc cggttaaaag
    21661 ccccccgccg cagcggaggg caaatggcaa ccttactcgc cctgttcagc agccggagct
    21721 tccggtgctg cagcaggttg agactgctca gtcgcttctt taatgctcag acggatacgg
    21781 ccctggcgat caacttccag aactttcacc ggtacttcct gacccatctg caggtaatcg
    21841 gtcactttct caacgcgttt gtcagcgatt tgagagatgt gtaccagacc ttctttaccg
    21901 ccgccgatgg caacaaatgc gccaaagtca acgatacggg tcactttacc agtgtagacg
    21961 cggcccactt cgatttctgc agtgatctct tcgatacgac gaatagcgtg tttcgctttc
    22021 tcgccgtcgg tcgctgcgat cttcacagta ccgtcatctt cgatttcgat ggtggtgcca
    22081 gtttcttcgg tcagggcacg gataacagaa ccgcctttac cgataacgtc tttgatcttg
    22141 tccgggttga tcttgatggt atggatacgc ggtgcgaact cagagatatc gccacgcggc
    22201 gcgttgatcg cctgttccat tacgcccagg atatgcagac gcgcaccttt agcctggttc
    22261 agcgcaacct gcatgatctc tttggtgata ccttcaattt tgatatccat ctgcaatgca
    22321 gagataccgt cgcgggaacc cgcaactttg aagtccatat cgcccaggtg atcttcgtcg
    22381 cccaaaatgt cagacagtac aacgtagttg tcgccttctt tcaccagacc cattgcgata
    22441 cccgcaacgg cagctttgat cggcacacct gcgtccatca gcgccagaga cgcgccgcac
    22501 acggaagcca tagaagagga accgttggat tcagtgattt cagacacaac acgtacggtg
    22561 tacgggaatt tgtccatatc cggcatgact gccagcacgc cgcgcttcgc cagacgaccg
    22621 tgaccaattt cacgacgctt cggagaaccg accatgccgg tttcgcctac ggagtacgga
    22681 gggaagttgt agtggaacag gaaggtgtcg gtacgttcgc ccatcagttc atcaagaacc
    22741 tgcgcgtcac gagcagtacc cagcgttgcg gtaaccagcg cctgcgtttc accacgggtg
    22801 aacagcgcag aaccgtgagt acgcggcagc acgccagtac gcacatccag accacgaatc
    22861 atatcttttt cacgaccgtc gatacgcggt tcgcctgcca gtacgcggct acgaacaacg
    22921 tttttctcga tagcgtgcag aatttcaccc agttcgtttt cgtccagggt ttcgtcttca
    22981 gcaagcagcg tcgcgatggt ttcagatttg atgacatcaa cctgcgcata acgctcttgt
    23041 ttgtcggtga tgcggtaagc atcactcaga cgagcttcag ccagtgcagc aacgcgcgcg
    23101 ttcagcgctt cgtttaccgg ctccggctgc cagtcccaac gtggtttacc ggcttctttc
    23161 accagttcat tgatgttctg aataacaacc tgctgttgtt catgaccgaa cactactgcg
    23221 cccagcatct ggtcttcgct cagcaattca gcttcagatt caaccatcag tacagcggct
    23281 tcagtaccag caacaaccag atccagtttg ctctctttca gctcgtcctg agtcgggttc
    23341 agtacgtact ggtcattgat gtaacctacg cgggcagcac caatcggacc attgaacgga
    23401 ataccagaca gagacagtgc tgcggaagca ccaatcatcg cgacgatatc cggattaact
    23461 tgcgggttaa cagaaaccac ggtggcgata acctgaactt cgttgacgaa gccttccggg
    23521 aacagcgggc gaatcgggcg gtcaatcaga cgcgcgatca gggtttcgcc ttcgcttggg
    23581 cggccttcac gacggaagaa gctacccggg atacgaccag cagcgtaagt acgctcctga
    23641 tagttaacgg tcagtgggaa gaagtcctga cctggtttgg cttttttctg gccaacaacg
    23701 gtaacgaata ccgcggtgtc atccatgcta accataacag cggcagtagc ctgacgagcc
    23761 atcatgccgg tttccagagt cacggtgtgt tggccgtact ggaatttacg aacgatcgga
    23821 ttaagcaatg taatatcctt tctctttctt agacagtacc ttacggcact ggtgttaata
    23881 cccgatcttc tgcgcatcct cgcgactaat gacaacccta acccagctct atgtgggtaa
    23941 agcctctcat tagccgcgcg aacctctgca acggaagatc attcatagca acaatacatt
    24001 agtttccagt gaattgctgc cgtcagcttg aaaaaagggg ccactcaggc ccccttttct
    24061 gaaactcgca agaattagcg acgcagaccc aggcgctcga tgagctgggt gtaacgtgct
    24121 acgtctttac gtttcaggta gtcgagcagt ttacgacgct gagaaaccat gcgcagcaga
    24181 ccacgacggc tgtggtgatc ttttttgtgc tctgcaaagt ggccctgcag gtggttgatc
    24241 tgtgcagtca gcagtgctac ctgaacttcg gtagaaccgg tgtcgtttgc gtcacgacca
    24301 aactcagaaa cgattttagc tgttgcttca gtacttagag acattttaaa actccaaagt
    24361 atatagaatg aaaggacgcc gatctctaat tcagcgatcc cagtgtacgt tacgcaaagt
    24421 gttaaacaat ttacgcgacg ttaagcggca gtattctact cgtagcgacc tgttatcgca
    24481 agacggttaa cattacgccg ggtattcaac caccaggcga cgaggcgcaa cgcggccttc
    24541 atcgtcaatt tcgcccatac cgataaattt gccgttctca ccttctgtaa cgcgaaccag
    24601 tccttccagc ggcgcaccgg atgtacgaac tgggttacca tttttgaagt aaacagaaga
    24661 cgttaacgga agattcacca ccgggtagtc cgaagctgga ctgtccattg gcatcagtaa
    24721 tggatcaagt aactccgcag ccggaatatc ctgctgttcg gcttgttcga ccagttcacg
    24781 cagatgttcc agggtcacca tccgttcaac cggatattta cttaccgcca gacgacgcag
    24841 gtaaataaca tgcgcgccac aaccgagttt ttcacccagg tcatcaatga tggtgcggat
    24901 ataagtgcct tttgagcagt gaatttccag ctccagctca ttgccttcgt ggcgaataaa
    24961 cagcaattca taaacggtaa tcgggcgcgc ttcacgcggt acttcaatgc cctgacgcgc
    25021 atattcgtac agttttttac cctgatattt cagtgctgaa tacatcgaag ggatctgttc
    25081 gatatcgcca cggaaagtat ccagcgccgc cgccagttgc tctgcgctaa aggttaccgg
    25141 acgttcttca acgatttgtc cgtcggcatc agaagtatcg gtacgctgtc caagacgcgc
    25201 aatgacccga tagcgtttgt cggagtccag cagatactgg gaaaacttcg tcgcttcccc
    25261 gaggcaaatt ggcaacatgc cagttgccag cgggtccagc gcaccggtat gcccggcacg
    25321 gttggcgtta taaatccgtt tcactttttg cagcgcatca ttgctggaca taccctgcgg
    25381 tttatccagc aacaaaacgc cgttaatgtc gcgaccgcga cgacgaggac gactcattag
    25441 tcctccttgc tgtcgtccgg gttaacacga cgttcttcgt catgtttgac cacgctggtc
    25501 accaggtttg acatgcgcat cccttcaacc agagagttgt cgtagaagaa ggtcagttcc
    25561 ggcacgatac gcaggcgcat cgctttcccc agcaggctgc ggatgaaacc agaagcttct
    25621 tgcaacgctt tgatgcccgc tttaaccgcg tcttcatctt tgtcgttgag gaacgtcaca
    25681 tatactttgg catacgccag gtcgcgagac atttcgacac cggaaacggt ggtcatcatg
    25741 cccaggcgag gatctttaat ttcacgctgc aggatgagag cgatctcttt ttgcatttcc
    25801 tgcgctacgc gctgcgggcg accaaattct ttcgccataa taaattctcc tgacaaaaaa
    25861 ggggctgtta gccccttttt aaaattaatt tcaggtggaa gggctgttca cgttggcctg
    25921 ataagacgcg ccagcgtcgc atcaggcagt ccatgcagga tgcggcgtaa acgccttatc
    25981 ccgcatggaa ccctaaaaac cttaagcgat ggtacgttgg atctcgatga tttcgaatac
    26041 ttcgatcaca tcgccagtgc ggacgtcgtt gtagttctta acgccgatac cacattccat
    26101 accgttacgg acttcgttaa cgtcatcttt gaagcggcgc agggactcca gctcgccttc
    26161 gtagataacc acgttgtcac gcagaacgcg gatcgggttg tgacgtttaa ccacaccttc
    26221 ggtaaccata cagcctgcga tggcaccaaa tttcggtgat ttgaacacgt cacgaacttc
    26281 cgccagaccg ataatctgct gtttcagttc cggagacagc ataccgctca tcgccgcttt
    26341 cacttcgtca atcaggttat agatgacgga gtagtaacgc agatccaggc tttccgcttc
    26401 aatcacttta cgtgcagagg catcagcacg tacgttgaag ccaaccagga tggcgttgga
    26461 cgccgcagcc agggtggcgt cggtttcggt gataccccct acgccagaac cgatgatctt
    26521 cactttaact tcgtcagtag acagtttcag caaggagtcg gagatcgctt ccacagaacc
    26581 ctgtacgtct gccttcagga cgatattcac ttcgtgaact tcgccttcgg tcatgttggc
    26641 aaacatgttc tcgagtttag atttttgctg acgcgccagt ttaacttcgc ggaatttacc
    26701 ctgacgatag agtgcaactt cacgcgcttt cttctcgtca cgtacaacgg taacttcatc
    26761 acccgcagcc ggaacgccgg acaggccgag gatttccacc ggaatggacg gacccgcttc
    26821 cagcacttcc tgacccagtt cgttacgcat cgcacgaaca cgaccgtatt cgaagccaca
    26881 cagaacgata tcgcccttgt gcagagtacc ttcacgtacc agaacggtag caaccggacc
    26941 acgaccttta tcgaggaagg attcgataac cgcaccgctc gccatacctt tacgtaccgc
    27001 ttttagctcc agaacttccg cctgcagcag gatagcgtcc agcagttcat cgataccggt
    27061 acccgccttc gcagatacgt gtacgaactg gctttcaccg ccccactctt ccggcaggat
    27121 gccatactgg gagagttcgt tcttaacacg atccggatcg gcttctggtt tatcgatctt
    27181 gttcactgca accaccaccg gtacctgcgc cgctttcgcg tgctggattg cttcgatggt
    27241 ctgcggcatc acgccgtcgt cggcagcaac aaccaggact acgatgtccg ttgcctgcgc
    27301 accacgtgca cgcattgaag taaacgcagc gtgccccggg gtgtccagga aggtgatcat
    27361 gccgttttca gtttcaacgt ggtatgcacc aatgtgctgg gtaatgccgc ccgcttcgcc
    27421 agaggccact ttcgttgaac gaatgtagtc cagcagagag gttttaccgt ggtcaacgtg
    27481 acccatgatg gtcacaaccg gcgcgcgcgg ttcagccgca gcccccgtgt cacggtcgct
    27541 cattaccgcc tcttccagct cgttttcacg acgcaggata actttgtggc ccatctcttc
    27601 agcaaccagc tgtgcggttt cctgatcgat aacctggttg atggttgcca ttgcgcccag
    27661 tttcatcatc gctttgatga cctgagagcc tttaaccgcc atcttgttcg ccagttcgcc
    27721 aacggtgatg gtttcgccga tcacaacgtc acggttaacg gcctgagctg gcttctggaa
    27781 gccttgctgc agggaagaac ctttacgttt tccgccttta ccgccacgta ctgctgcgcg
    27841 tgcttcttca cgatcagctt ttgattcagc gtgtttgttg cctttcttcg gacgcgctgc
    27901 tttcgcgtta cgaccacggc cacggccgcc ttcgacttca cgatcgcttt cgtcttctgc
    27961 ctggcgagca tgttgagaag ttgtgacatg ataatcgctg gaatcttcag tcggttccgc
    28021 gttatcagtc catttgtttt cttccgccat acgacgtgct tcttcagcaa cgcgacgtgc
    28081 ttcttcttcg agtttacgac gcgcttcttc ttcagcttta cgcttgagct ctgcagcttc
    28141 ctgctcacgg cgggcttttt cagcctgggc gtttttagtc atatcgtctt gttgattgct
    28201 cactttgtct ttttccgcag cttcacgttt cgcttgttca gcagcttcac gcttagcttg
    28261 ttctgcggcc tcacgttcag ctttttgttg cgcctcgcgt ttagccgatt cttctgcctc
    28321 acgacgggct tgctcttccg cttcacgctg cgcttgctct tccgctgcaa ggcgttcagc
    28381 ctcttgcgga tcgcgtttca caaaggtgcg tttcttgcgg acttcgattt gtaccgattt
    28441 gctttttcca ccggtaccag gaatgttaag ggtgctgcgt gttttacgtt gcagcgtcaa
    28501 tttgtccggg cctgaatttt tctgattcag gtggtcaatc aaagtctgtt tctcttgtgc
    28561 agacacagag tcgtcagcag acttccggat acctgcatca gcaaattgct gtaccaggcg
    28621 ttccacggag gtctgtcgct ctgcggccag cgttttaatc gttacatctg tcatgctgtt
    28681 ccttcctgct acagtttatt acgcttcgtc accgaaccag caaatattac gggcagccat
    28741 aatcagtgct ccggcttttt cgtcggtcaa cccttcgata tcagccagat catcaatgcc
    28801 ctgttcggcg agatcttcca gcgtacaaac gccacgggcg gccagtttga atgccaaatc
    28861 acgatctacc ccttcaaggt tcagcagatc gtcagccggt ttgttatcac cgaggctttc
    28921 ttcctgggcc tgtgcaatgg tggccagtgc atttttagca cgctcgcgca gtgcttcaac
    28981 ggtcggctca tcaaggcctt cgatttccaa cagctctttc atcggaacat aggccagttc
    29041 ttccagcgtc gagaaacctt cttctaccag aacagtcgcg aagtcttcgt cgatgtcgag
    29101 atatttggtg aaggtgtcga tcgctgcgtg cgcttccgcc tgatgcttag cctgcaggtc
    29161 gtcaacggtc attacgttga gttcccaacc gctcagctgc gaagccagac gcacgttctg
    29221 accgttacgg ccaatcgcct gcgccaggtt accggcttca acggcgatat ccatggtgtg
    29281 tttatcttca tccaccacga tagaagcaac gtctgccggt gccattgcgt taatcacaaa
    29341 ctgcgccggg ttatcatccc acaggacgat atcgatacgc tcgccgccca gttcagtaga
    29401 aaccgcctga acacgcgcgc cacgcatacc tacacaggca cctaccggat cgatacgttt
    29461 atcgttggtt ttcaccgcga ttttcgcacg agaacccgga tcgcgagccg ctgctttaat
    29521 ttcaatcact tcttcgccga tttctggcac ttcaatacgg aacagttcga tcagcatttc
    29581 cggcttggaa cgagtgacga acagttgcgc gccacgcgct tccgggcgaa cggaatagag
    29641 cacgccacga acgcggtcgc cagggcggaa gttttcacgc ggcagcatat cttcgcgcag
    29701 gatcacggct tcagcattgt tgccgagatc caaagagatg ttgtcgcggt ttactttttt
    29761 caccacgccg gtgatgattt caccttcgtg ttcacggaac tgatcaacca ccatcgcacg
    29821 ttcggcttca cgcactttct gcacgataac ctgttttgcc gtctgggtag tgatacggtc
    29881 aaaggtaaca gactcaatct gatcttcaac gtaatcgccc aggttcaggc tttcatcttc
    29941 ataacgtgcg gcttcaaggg tgatttcctt ggtcggctgg gtgacttcat caacaactaa
    30001 ccagcgacgg aaggtgtcaa aatcaccgct tttgcgatcg atctgtacgc ggacgtcgat
    30061 ctcttgttca tattttttct ttgttgctgt cgccagcgcg ctttccaatg cttcgaaaat
    30121 cttctcgcga ggtagcgcct tttcattgga tacggcttca actacagcca aaatttcttt
    30181 gttcatcgcg ggcttttcac ctcatccaga ctattaaaag tggggaacca ggttcgcctt
    30241 ctggatatta ctcagcgcga acacttcatc tttaccttcg acggtaactg tgatcatttc
    30301 accgtctacc gctttgataa cgccctgcca tttacgacgg ttttgtaccg ccatacggag
    30361 aaccagagtc acctcttctc cgacaaaacg ggcgtagtgt tcagccgtga acagtgggcg
    30421 atcgagaccc ggtgaggaga cttccaggtt ataagcaacg gtgatgggat cttcaacatc
    30481 cagcacagca cttacctggt ggctcacatc agcacaatca tcaacattga tgccatcttc
    30541 actatcaata tagatgcgca gtgtggatgt gcgaccgcga ataaattcga tgccaaccag
    30601 ttcaaaaccc agggcctcaa ctggcgcagt aatcatctct gttaattttt gctctaatgt
    30661 ggacaagccc acccccaaga cataaaaaaa gggcttaaag cccagttatt ctgtagtcag
    30721 ataacaaaaa accccgataa atcggggctt tatataactg aaccctataa ccgcaactgc
    30781 ggtctggagc actttccaga aggatttttt caaatcccac tacgaaggcc gaagtcttca
    30841 cagtatattt gaaaaaggac tctaagggaa agtggttgcg ggggccggat ttgaaccgac
    30901 gaccttcggg ttatgagccc gacgagctac caggctgctc caccccgcgc ctgaaacgtg
    30961 gcaaattcta ctcgttttgg gtaaaagatg caaatactgc tgggatttgg tgtaccgaga
    31021 cgggacgtaa aatctgcagg cattatagtg atccatgcca cattttgtca acgtttattg
    31081 ctaatcacgt gaatgaatat ccaattcact ttcatttgtt gaatactttt gccttctcct
    31141 gctctccctt aagcgcatta ttttacaaaa aacacactaa actcttcctg tctccgataa
    31201 aagatgatta aatgaaaact catttatttt gcataaaaat tcagtgagag cggaaatcca
    31261 ggctcatcat cagttaatta agcagggtgt tattttatga cgacgattct caagcatctc
    31321 ccggtaggtc aacgtattgg tatcgctttt tctggcggtc tggacaccag tgccgcactg
    31381 ctgtggatgc gacaaaaggg agcggttcct tatgcatata ctgcaaacct gggccagcca
    31441 gacgaagagg attatgatgc gatccctcgt cgtgccatgg aatacggcgc ggagaacgca
    31501 cgtctgatcg actgccgcaa acaactggtg gccgaaggta ttgccgctat tcagtgtggc
    31561 gcatttcata acaccaccgg cggcctgacc tatttcaaca cgacgccgct gggccgcgcc
    31621 gtgactggta ccatgctggt tgctgcgatg aaagaagatg gcgtgaatat ctggggtgac
    31681 ggtagcacct ataaaggaaa cgatatcgaa cgtttctatc gttatggtct gctgaccaat
    31741 gctgaactgc agatttacaa accgtggctt gatactgact ttattgatga actgggcggc
    31801 cgtcatgaga tgtctgaatt tatgattgcc tgcggtttcg actacaaaat gtctgtcgaa
    31861 aaagcctact ccacagactc caacatgctt ggtgcaacgc atgaagcgaa ggatctggaa
    31921 tacctcaact ccagcgtcaa aatcgtcaac ccaattatgg gcgtgaaatt ctgggatgag
    31981 agcgtgaaga tcccggcaga agaagtcaca gtacgctttg agcaaggtca tccggtggcg
    32041 ctgaacggta aaacctttag cgacgacgta gaaatgatgc tggaagctaa ccgcatcggc
    32101 ggtcgtcacg gcctgggcat gagcgaccag attgaaaacc gtatcatcga agcgaaaagc
    32161 cgtggtattt acgaagctcc ggggatggca ctgctgcaca ttgcgtatga acgtctgttg
    32221 accggtattc acaacgaaga caccattgag cagtatcacg cgcatggtcg tcagttgggc
    32281 cgtctgctgt atcaggggcg ttggtttgac tcccaggcgc tgatgctgcg tgactctctg
    32341 caacgctggg ttgccagcca gatcactggt gaagttaccc tggagctgcg ccgtgggaac
    32401 gattattcaa tcctgaatac cgtctcagag aacctgacct acaagccaga gcgtctgacg
    32461 atggaaaaag gcgactcggt gttctcgcca gatgatcgta ttggtcaatt gaccatgcgc
    32521 aacctggata tcaccgatac ccgcgagaaa cttttcggtt atgccaaaac tggcctgctc
    32581 tcctcctctg ccacttcagg cgtgccgcag gtggagaatc tggaaaataa aggccagtaa
    32641 ttcgacatca accctgccct tcaggggtgg ggttaccttg cttatcctct gtaaactcct
    32701 ttctgagcat cacataatcg aaaacatcat ggtttgcatc cacaacccgt gagtctcctt
    32761 tatagtgtgc aatcacttcc tccagcgttt gcggctgttc cggctttgtt acccccatcc
    32821 acgcattaat aaggtaatta ttgtacgcag tggaaaagat atcgttttct gttgtgcgat
    32881 ccacgccatc cccaagaacg gggctatacc agataaacat cgggacatga tatgcctgct
    32941 ggctggcctc cctgcctcca tgaaaataga cgttcttctt cgtagggtcg cgttccaggc
    33001 cgtggtcggc aaaatacatg accgaggcgc ggcgatcttt tagtaattca aaaacctgac
    33061 ctagcaaact gtctgtgtaa tgaatggagt tgtcatagca ggcatcctga tcgtcctgcg
    33121 gttgaaacac ggcgctggat tgcggatagg cgctacaagc cggttcatgg cttccattta
    33181 aatgaagaac aatcagtttc ttttgctgcg tcttttgctg taacgcttgc gataaatgcg
    33241 gcaacaacaa ttcatcaaat cctctgacat agactgtttc catggcgcgc atggcgatac
    33301 tggtaactgc tgtaccattc tgccgaaaag cggattgcga gcttagccag aaagtctgaa
    33361 atcctgcttg attagccata ttaataatgt tgtcggggta attatgaatg tcatgactca
    33421 aaacagaatc agcagttaaa gaaaggggaa ccgacagcgc agtgtaaggt gcgccgctta
    33481 ttgcttgatt aaacagtttg atctgttttc tttgtgcttc aacttgcggt gtcgtagagc
    33541 gtgtatatcc atacaaagac atattgtcga cacgtacaga ctcccccaca atcaacacgt
    33601 aggtatcaat acctgtatcc ctgactgata attgaaaata cggcaccgtg tttgcaattg
    33661 agagtaatct ttgatgctct ttcgctgcta aagcaaaata gttgagatta aaaaacggcg
    33721 tataggtagc aaatcgcgac gctagtatat atggactgaa cgctttttta ttttttgcat
    33781 ctttataagc aaattgacaa gcggaaaata aactgcccga aatgacaatc agcaataata
    33841 ttcctgtcac tttttttgtc ggcaaggaaa catcatattt tattattact gccaaaaaaa
    33901 gaagggataa aaaagcaaaa gcacatagat aagggatata catccccagc attttgacaa
    33961 cttcatccgg atcactctgc agcacactaa tcgcaaatcc atcattgaaa gttgtaccaa
    34021 aggtacacca tgaatagagg ctaatactca tgtctgccgc agtcagtaac acaaatggtg
    34081 cggcaacaag caggcgaagc ggaagggatg atatacgttt aacaaccagg atggtcagga
    34141 cgaagaacag caatcgctga accatatgcg ctccggaaga ggcgactaag ttcgtaatac
    34201 caaaaacaat aacacaaaga tacaacaacc aatgagattt aaaacttcta gcaaatttgt
    34261 tgaatactgt catccagaaa tccaagttca caaccaatat aaacaattat caacaatgtt
    34321 caattttata tcagacatgt ttttcaactc tgatccatat cagaccgaaa cactgttagt
    34381 tttttctttt taaatgatgc ggccattgtt ctcagtaatt aaataacatt atcaatgcgt
    34441 ctctaaacat tacgcagaac gtagccatca gtagttatac tgacaggagc aggatggttt
    34501 atcgagaagt aaacatatcc gtattcgtac cggaactgga gttgacacaa taaagtgcca
    34561 attatgtcag cagtagggaa aagtttataa ctaaggcgta ccggcaccat cgtttcaaag
    34621 taccagctac gagtaaagca actggacgag atacagatac ctgacaacca ttcctcagac
    34681 caggaccaaa acgaaaaaag acgcttttca gcgtctcttt tctggaattt ggtaccgagg
    34741 acgggacttg aacccgtaag ccctattggg cactaccacc tcaaggtagc gtgtctacca
    34801 attccaccac ctcggcacgg atactacttt ttagttcggg atatcgctgg tcggcttagc
    34861 cggagcagct ggctgagttt gttcggtttt cgccggcgca ctcaggtttt cccattcgct
    34921 acctttattg gttttattgc tattgatgtt acccagcacc agactgatga tgaagaataa
    34981 cgttgccagc agcgccgtca tgcgggtcat gaagttacca gaaccacttg aaccaaacag
    35041 cgtagcggaa gcgcctgctc cgaaggaggc tcccatatca gcgcctttac cttgctgcag
    35101 catgatcaga ccaacaaggc caattgccac aataaggaaa actactaaaa gagcttcgta
    35161 cataatcaac ctgttccttg cggagttgcc gcgtaccaat gcttcaacca ataaagcggg
    35221 agtttttaat ctttcccact gaagcgggtg tgaatactaa ccaaagcgaa tgaccttcgc
    35281 aagggcaatt ttatcgcatt gtatcaactg cggaaaaaaa cagcaaaacc gatgtgttcg
    35341 ctgagaaaaa aggcgacaat cgccgccttt ttagccagtt atctaacgct ttaaacggct
    35401 tttactgcat cggcgatgcg gtgtgcaaat tcagtcacct gcgcttcgtc ttcgccttcc
    35461 accatcacgc gaattaacgg ttcggtgccg gatttacgca gcaacacgcg tccacggttg
    35521 cccagcgcag cttcaacctc tgcggtcacg gctttaactg actcatgctc aagtggatcg
    35581 ccgctacctg cggtgtaacg tacgttaacc agaatctgcg ggaacatttt catgccgctg
    35641 caaaggtcgt gcaggctcat atggttacgt gccatcgccg ccagcacctg caagccagca
    35701 acgatgccgt caccggtagt agttttatcc agtaggatca catgaccgga attctctgca
    35761 ccgatacgcc agcctttctc ctgcattttt tccagtacgt agcggtcacc cactttcgcg
    35821 cgcgcaaatg gaattcctaa ctgtttcagc gccagttcaa gccccatgtt gctcatcaat
    35881 gtacccacag cgccaccacg cagctggccc tgacgaagac cttcacgcgc gatgatatac
    35941 atgatctgat cgccatcgac tttattgcct tcatggtcga ccataatcac gcgatcgcca
    36001 tcgccgtcga aggcaatacc gagatccgct ttttcagcca gcacacgagc ctggagcgcg
    36061 cgaacgtcgg tagcccccac ttcggcattg atgtttacac cgtttggctc acaaccgata
    36121 gcgataacgt tcgcccccag ttcgcgcagc acgttcggcg cgatgtgata agtcgcaccg
    36181 tttgcacaat ccaccacaat cttcagttca ctgaggctaa gttcgttcgg gaacgtggct
    36241 ttgcaaaact cgatatagcg acccgcggca tcaacgatac ggctggcttt acccagttct
    36301 gccgaatcaa cgcagctgat ctccttttcc atttccgctt cgatggcctc ttctaccgca
    36361 tccggcagtt tggtgccgtc gatagagaag aatttaatcc cattatcgta gaacgggtta
    36421 tgcgatgcag atatcacaat tccggcctct gcgcggaagg tacgcgtcag ataagccacg
    36481 gccggtgttg gcatcgggcc agtgaagagt gcggaaaggc ccgctgccgc cagacccgct
    36541 tccagtgctg actccagcat atagccagaa atacgcgtgt ctttaccaat aataatctta
    36601 cgggagccgt ggcgcgccag cactttaccc gcggcccaac ccagcttaag cacaaaatca
    36661 ggtgtgatcg gcgcatcccc tacacgacca cgaatcccat cggtaccgaa atatttacga
    36721 ttactcatag cgtttgtttt cctttgcaga cagagtggct tccaccaccc gcatcgcttc
    36781 tacggtttct ttgacgtcat gaacacgaat gatgtgcgcg ccttgcattg cggcaatgac
    36841 cgcacaggcc agactaccgc tcaggcgctc ggacggcacc acgttcagca gctgcccaat
    36901 catcgatttt cgtgacatac ccaccaacag cggcaggttg aaatggtgaa attcagccag
    36961 gcgcgccagt aatgaatagt tatgggagag atttttaccg aaaccgaatc cggggtcgag
    37021 caacaatttc tcttttgcga tacccgcctg ctcgcaacgt gctatttgct caataaagta
    37081 gcgattcact tctgcaaaga catcgtcata cttcggagct tcctgcatgg tttttggatt
    37141 tccctgcata tgcatcagac aaaccggtaa accggtttct gcagccgcct ccagagcgcc
    37201 aggttcggaa agggagcgga tatcattaat aatgtgagcg ccaactttcg ctgactcacg
    37261 gatgacttct ggtttggatg tatcgaccga gatccagact tcgaagcgtt gagcaattgc
    37321 ctcaaccaca ggaataacac gttgcaactc ttcttcaacg ctaacttccg ccgcccctgg
    37381 gcgcgtggac tcgccaccaa cgtcaatgat cgtcgcgcca gcattgatca tcagattcgc
    37441 atgtttcacc gcatctatca gcgagttatg cgtgccacca tccgaaaagg aatcaggcgt
    37501 gacgttgagg atccccatta cgtgaggatg gctaaggtcc agtgaagtac cctgggcaaa
    37561 gagtttcatg atgttatccc tggtatgaat tgataagaaa aaaccccgga gcacgccccg
    37621 gggttttcgg tacaaataca gtcatctgat gcgggaactt acttgtcgcc taactgctct
    37681 gacatggtgt tacccgggtt cggcgtacgc ggttcatcaa ccggacgagg agcctttgga
    37741 ctaccattgt cgccagaatt gttagaagcg cctggttctt cccagcccgc tggcggacgt
    37801 acatcgcgac gtgccatcag gtcatcaatc tgcggtgcgt cgatagtctc atatttcatg
    37861 agagcatctt tcatcgcatg cagaatatcc atattgtcgg tcagaagctg acgcgcacga
    37921 ttatagttac gctcaatcag tgctttcact tcctggtcga tgatacgtgc agtttcatcg
    37981 gacatatgtt tcgctttcgc tacgctacgg ccgaggaata cttcaccttc ttcttccgcg
    38041 tacagcagtg gacccaattt ctcagagaag ccccactggg tcaccatgtt acgtgccaga
    38101 ttggtcgcaa ctttaatatc gttggacgca ccggtagaaa catgttccgg cccatagatg
    38161 atctcttctg ccagacgacc accgtacagc gtagaaatct ggctttccag tttctgacgg
    38221 ctggcgctga ttgcgtcgcc ctcaggcaag aagaaagtca cacccagcgc acgaccgcgt
    38281 gggataatcg tcactttgtg caccggatcg tgttccggca ccaggcgacc gataatcgca
    38341 tgacccgctt cgtggtaagc cgttgattct ttctgcgctt ccgtcatcac catggagcga
    38401 cgttccgcac ccatcatgat tttgtctttc gctttctcga actcaaccat cgacacaacg
    38461 cgtttgttgc cacgagcagc gaacagtgcc gcttcgttca ccaggttcgc caggtcagca
    38521 ccggagaaac caggagtacc acgggcaatg attgccgcgt cgatatcggg ggccaatggt
    38581 acgcgacgca tgtgaacttt caggatctgc tcacgaccgc gaacatctgg caagccgacc
    38641 acaacctgac ggtcgaaacg gccaggacgc agcagggccg ggtcgagaac gtccggacgg
    38701 ttagtcgcgg cgataacgat gataccttcg ttaccttcga agccatccat ctcaaccagc
    38761 atctggttca gagtctgttc acgttcatcg tgaccaccgc ccagaccagc gccacgctgg
    38821 cggcctacgg cgtcgatttc atcgataaag atgatgcacg gtgccgcttt cttcgcctgt
    38881 tcgaacatgt cacgaacacg ggatgcaccc acaccgacga acatttctac gaagtcagaa
    38941 ccggagatag taaagaacgg aactttcgct tcgcctgcaa tcgctttcgc cagcaacgtt
    39001 ttaccggtac ccggaggacc gaccatcagg acgcctttcg ggatcttacc gccgagtttc
    39061 tggaagcggc tcggctcgcg cagatactct accagttcag caacttcttc ttttgcttcg
    39121 tcgcagcccg caacgtcagc aaaggtcgtt ttgatctgat cttccgtcag catgcgcgct
    39181 ttgctcttac caaacgacat ggcacctttg ccaccgccgc cctgcatttg acgcatgaag
    39241 aagatccaga caccaatcag caacagcatc gggaaccagg agatgaagat agaagccagc
    39301 aggcttggtt cttcaggcgg ttcaccgaca accttgacgt tcttggtcaa caggttatcc
    39361 agtaatttcg gatcctgaac cggaatgtaa gtggtataac ggttactatc tttcttggta
    39421 acgttgattt cacgtccgtt gatacgcgct tcacgaacct ggtcgttatt gacctcttgt
    39481 aggaaggtag agtaatccac cttacggcca ttagactcgc tgggcccaaa gctctggaat
    39541 actgacatca gcacaacggc aatgaccagc cagagtatta ggtttttcgc catgtcactc
    39601 aagggattaa cctcttatta caactgtgtt aaaaacagcg tcaggatact ctatatccag
    39661 catctttcaa actttcgtct gaaatctccc ggttagggtt tacgcccggt cgctacaata
    39721 tacacttccc gcgaacgtgc acgagaagag tccggcttac gaactttgac cttcgtaaac
    39781 agggagcgaa tttcccttag atactcatcg aaaccttcgc cctggaacac cttcactaca
    39841 aaactgccac ctggcgctaa tacatcacga cacatttcta acgccagttc caccagatac
    39901 atggcacggg ggatatccac cgccggtgtt ccgctcatgt ttggtgccat atcggacatg
    39961 acaacctgga ctttgctgtc gccaacgcgc tccagcagtg ctttcatcac cagttcatca
    40021 cgaaaatcgc cctgaagaaa gtccacacca acgataggat ccataggtaa aagatcgcaa
    40081 gcgatgatgc ggcctttgcc gccaatttgg gtgaccacat attgtgacca accacccgga
    40141 gcagcaccaa ggtcgacaac cgtcattccc ggtttaaaga gtttgtcact ttgctgtatt
    40201 tcatcaagtt taaaccaggc acgggaacgt aacccctttt tctgtgcctg ttgaacatat
    40261 ttatcgctaa agtgttcctg aagccagcgg ctggagctgg cagaacgctt cttacctgtc
    40321 atttaacttt cccatgggga taactcatcg taaccaattg cgtaaatttt tacgcgccta
    40381 tttggtgata tatgggagat ggcggtagaa tgacccgttt tcaatcccaa cgtaagcaaa
    40441 aaatacgatg aatctgagta ctaaacaaaa acagcacctg aaaggtctgg cacatccgct
    40501 caagccagtt gttctgcttg gcagtaatgg tttgaccgaa ggggtgctgg ccgagattga
    40561 acaagcgtta gagcaccatg aactcatcaa ggtgaaaatc gccaccgaag atcgcgaaac
    40621 taaaaccttg atcgtggaag ctatcgtgcg cgaaaccggc gcctgtaatg tacaggtcat
    40681 cggtaaaacg ctggtgcttt atcgcccaac taaagaacgt aaaatctcgc tgccacgcta
    40741 agattatcct aaagttacac acatttgctg tgtaaaacga ggggttttcc gcaggcagga
    40801 gagcaaaatg ccacgctctg ttcgttgata aaaggccgca tagcggcctt tttcctttct
    40861 ttacaataca tcaacatctt gagtattggg taattcttac aggtattcca ccttaattac
    40921 ttcaaattct acttcgccgc ccggcgtttt gatgaccaca acatcatctt cttctttgcc
    40981 gatcaggcca cgagcaatag gcgagtttac agaaatcagg ttttgtttaa agtcagcttc
    41041 gtcatcgcca acgatgcgat aagtctgttc ttcgtcagaa tccagattca gcaccgttac
    41101 ggtagcacca aaaataacgc gcccattgtt gggcattttg gtgacatcaa tcacctgcgc
    41161 gttcgacagc ttggcttcga tgtctttaat acggccttcg cagaaaccct gctgttcacg
    41221 agctgcgtgg tattcggcgt tttctttcag gtcgccatgc tcacgcgctt ccgcgatagc
    41281 agcaatgatt tcaggacggc gcacagattt cagaaaatcc agctcttcgc gtaatttttc
    41341 agcgccgcgt aaggtcatcg gaatagcttg catttgttat acctcttgaa tattcctgat
    41401 ggggcaagtc ttcacccacc ccggctgttc ggcctgcccg gcataactcc tcaccgggac
    41461 cagaagcaaa aaaataccga cccgggtaca agtcccaggt cagctacaat tcacattttg
    41521 atagtcattt taccctgaag ttcccgaagg gtcatcgttt actttatagg gcgttgcgcc
    41581 gtagtatgac ggctcgattc caggttgtta gcgcgagatt atgcgatttt ccagatttat
    41641 catcggattg accagctgta tagcgttcag tgttcaggcc gcgaatgttg atgagtacgt
    41701 tactcaactc cccgctggtg ccaaccttgc cctgatggtg caaaaagtcg gcgcgtcggc
    41761 ccccgctatt gattaccaca gtcagcagat ggcgctgccc gccagtacgc agaaagtgat
    41821 tactgcgctg gcggcgttga ttcaactcgg ccccgatttt cgtttcacca cgacgcttga
    41881 aaccaaaggc aatgtggaaa acggcgtact taagggtgac ttagtggcgc gatttggtgc
    41941 cgatccgacg ttaaaacgtc aggatattcg caatatggtc gcgactttga aaaaatctgg
    42001 cgtcaaccaa atcgatggca atgtgttgat agatacctcc attttcgcca gccacgataa
    42061 agcccccggc tggccatgga atgacatgac acaatgcttt agcgctccgc ctgccgctgc
    42121 catagttgac cgcaactgtt tctccgtctc gctctacagt gccccaaaac ctggtgatat
    42181 ggcttttata cgcgtggcat cttattaccc cgttacgatg ttcagccagg tacgcaccct
    42241 cccccgaggt tctgccgaag cgcaatactg cgaactggat gtcgtaccag gcgacctgaa
    42301 ccgctttacg ctgacgggat gcctgccaca acgttctgag ccgctcccgt tggcttttgc
    42361 cgtgcaggat ggagccagct atgccggggc aattctgaaa gatgagttaa aacaggcagg
    42421 tatcacctgg agcggaacac tgctgcgcca gactcaggtt aacgaacctg gaacggtagt
    42481 tgccagtaaa cagtcggccc cgttgcacga tctgcttaag attatgctga aaaagtcgga
    42541 caacatgatc gccgatacgg ttttccgcat gataggccat gcgcgcttca atgtgcctgg
    42601 aacatggcgg gccgggtcgg acgccgtgcg tcagatcctg cgccagcaag ccggtgtcga
    42661 tattggaaac accattattg ccgatggttc agggctttcg cggcataacc tgattgcccc
    42721 cgccaccatg atgcaggtgc tgcaatacat tgcccaacac gacaatgaac ttaactttat
    42781 ctccatgctg ccgcttgcgg gctatgacgg ctctttgcag taccgtgcag gtctgcatca
    42841 ggcgggcgtg gatggaaaag tctcagcgaa aaccggttcg ttgcaggggg tatataacct
    42901 ggcgggattc attaccacag cgagcgggca acgaatggcg tttgtacaat atctttctgg
    42961 ctatgcagta gaaccggcgg atcagcgtaa tcgccgtatt ccgttagtgc gttttgaaag
    43021 ccgtttgtat aaagatattt atcagaacaa ttagtcaaaa agaaaccccg gcacatggcc
    43081 ggggttttgc tgattaacgc ttgtaaatga actcaacgcc ttcttcgtcg tcttcgtccc
    43141 agtcatcatc ccagtcctca tcatcctctt cagcaatctc ttcaagctgc tggcgatgat
    43201 aatcatccca catgaattcg actttctctg gctgtttcgc ttcttcagcc tgcacgaccg
    43261 ggttttcaat gataaaggtc atcacatccc agcagagatc tttcacgccc agtccactcg
    43321 ccgcagagat cagataatat ttatcttccc agcccagcgc ttcagcaatc gctttcgctt
    43381 tctcttcagc ttctgcctta tccagcagat cgatcttatt gaacactaac caacgtggtt
    43441 tcgccgccag atcctggctg tatttttcca gctcgctgat aataatacgc gcgttttcaa
    43501 ccggatcggt gccgtcaatc ggatcgatat cgatgaggtg caacaggacg cggcaacgtt
    43561 ccaggtgctt caggaagcga atgcccagac ctgcgccttc cgcagcgcct tcaatcagtc
    43621 ctggaatatc ggcaacaacg aagctctttt cgttgtccat tcgtaccaca cccagacttg
    43681 gcaccagagt ggtaaacgga taatccgcca ctttcggttt agccgccgat accgcacgaa
    43741 taaaggtcga tttacccgcg tttggcatcc ccaacatacc gacgtcagcc agcagcatca
    43801 gctccagcag cagctcacgc ttatcgcccg gcgtaccgtt agttttctgc cgtggtgtac
    43861 ggttaactga cgatttgaaa cgggtattgc ccagaccgtg ccagccgccc ttagcaacca
    43921 gcagacgctg accgtgtttg gtcatatcgc ccatggtttc accagtaccc tggtcgatta
    43981 cacgcgtacc taccggcact ttaattgtga cgtctttacc gcgcttaccg gtacagtcgc
    44041 ggcttgcgcc attctgaccg cgctctgcac ggaaagattt ttcaaaacga taatcgataa
    44101 gcgtgttcag gttctcgtcg gcttccatcc atacgtcacc accatcaccg ccgtcgccgc
    44161 catccgggcc gcctttcgga atatactttt cgcggcggaa gctcacgcaa ccattaccgc
    44221 catcacctgc aacgaccaga atcgatgctt catcaacaaa cttcatttta ttctccgtaa
    44281 atcattcgcc tgcgcggggt tgcgatacca ccgttgtatg cttacgtaat ccgccccaaa
    44341 tacgatgacc aatggcggaa tacatcgcgc ccgcaaccac gacaaacgca ccgagataac
    44401 ctaaaaggtt taacatcggt ctggcgaaga aatcgggtca ggccagtgat aaaagatctg
    44461 aaaaaaacag cgtaaacagt ggggtgagcg tgatgatcgc gctcacctgc gctgcctgcc
    44521 agcgagccat cgcttccgcc agggcgccat atcctaccaa ggtattcagt ccgcaaaaaa
    44581 ttaaacatgc gagctgccag tggctaagct gcgctatcac tccaggcttt gccagaggga
    44641 agagcgcaat tgtacataaa gtgtacagta aaaacaggat ctgcggtgag gccagccgac
    44701 gcaataaaac cttttgcgcc acgccataac tcacccaaac cgtcgccgca ccgaccccaa
    44761 agataactcc ccaggtgtaa tcggtgagct ttgtaaatat ctcgaccaga ctggtgttaa
    44821 aaaacatcac caggccgctc aggagcatca atgcccctac aacctgagtg ctgcgcattt
    44881 tctctttcag gataaatacg ctggcaacca tcatgccaac tggcgagagt tgcccaatca
    44941 cctgcgaagc ggtcggactc aggtattgca aggatgagct gaacaggatg aagttcccaa
    45001 acagcccggc ggtcgccact gccaacaaaa tcaaccagcg tggcttacga aacacgcgta
    45061 atggcggcaa cctcttcttc accgcaagaa tggcaccaag gccaatactc gccatcaaga
    45121 aacggtaaaa cacgattgtc ggaggttcca tcacctccag cacctgcttc attgcgattg
    45181 gcaacgcccc ccagcaaatt gctgtggtga gcgccaaaag aatgccaatg cctgcctgct
    45241 gcttcatacc gtattccctg caaagcgcat ttgcggatta acgtcgcacc atgcgcattt
    45301 ttaccggtta tcgaatgtaa aaagccccgc aacgtgttgc ggggctttca tccgttaccg
    45361 ggacgcgaaa aacttattca gcttcgatgc tgataaattt acggtttttc gggcctttaa
    45421 cttcgaattt cactttaccg tctgctttag caaacagagt gtggtcacga ccgcaaccta
    45481 cgttagcgcc agcgtggaat ttggtaccac gttgacgaac gatgatgcta cccgccagaa
    45541 cggattcgcc accgaaacgc ttaacgccca ggcgtttagc ttctgaatcg cgaccgttac
    45601 gtgtggagcc gccagccttt ttatgtgcca tttgaaatct ctcctcaggt cttaggcgct
    45661 gatgccagta attttcacat cagtgaacca ctgacgatgg ccctgctgct tacgatagtg
    45721 tttacgacga cgaaacttaa cgattttaac tttctcgcca cgaccgtgag caacaacttc
    45781 agctttgatt acgccgccat caacgaaagg aacgccgatt ttgacttctt caccgtttgc
    45841 gatcatcagc acttcagcga actcaacagt ttcgccagtt gcgatgtcca gcttttccag
    45901 gcgaacggtc tgaccttcgc ttactcggtg ttgtttacca ccactttgga aaaccgcgta
    45961 catataaaac tccgcttccg cgcacacctt ttcaatgatt cagagtgcgc tataaatatt
    46021 cacaataggg cgcgaatatt acgcaaaacg cacgcctttg acaagtgcta cagtcaatac
    46081 acgaagaaaa aaaacacaac ttgtacggta acgtttatct gtgccatttt ttcagtacaa
    46141 tcactctata ttcctaacca taaaccctaa gttgcctttg ttcacagtaa ggtaatcggg
    46201 gcgaaaagcc cggcttttgc gatgaattta gaaaaaatca atgagttaac cgcgcaagat
    46261 atggcgggtg ttaatgcggc aatccttgag cagcttaatt ccgacgtcca gctgatcaat
    46321 cagttaggct attacatcgt cagcggcggc ggtaaacgta ttcgtccgat gattgctgta
    46381 ctggctgcac gagctgttgg ctatgaggga aatgcgcatg tcaccattgc tgccctgatc
    46441 gagtttatcc acacggcgac tctgctgcac gacgacgttg tggatgaatc agatatgcgc
    46501 aggggtaaag ctaccgccaa cgctgcattt ggcaatgccg ccagcgtgct ggtaggcgat
    46561 tttatttata cccgcgcgtt ccagatgatg accagcctcg gttcgctcaa agtgctggaa
    46621 gtcatgtcag aagccgtaaa cgtcatcgca gaaggtgaag ttctgcaact gatgaacgtt
    46681 aacgatccgg acatcactga agaaaactac atgcgcgtta tctatagcaa aaccgcgcgt
    46741 ctgtttgagg ctgccgcgca gtgttccggg attctggctg gctgtacgcc ggaagaggag
    46801 aaaggcctgc aggattatgg gcgctatctc ggcactgctt tccagttgat cgacgattta
    46861 ctcgattaca atgccgatgg cgaacagtta ggtaaaaatg tcggcgacga tctgaacgaa
    46921 ggtaaaccga cgctgccgct gctgcatgcg atgcatcatg gcacaccaga acaggcacag
    46981 atgatccgta ccgccatcga acagggtaac ggtcgccatc ttctggaacc ggttcaggaa
    47041 gcaatgaacg cttgtggatc tcttgaatgg acgcgtcagc gtgccgagga agaagcagac
    47101 aaagccatcg cagcattaca ggtgctcccg gacacccctt ggcgagaagc actcatcggc
    47161 ctcgcgcaca tcgctgttca acgcgatcgt taatcccctc ccttcatccc gcgcagtgcg
    47221 cgggatgatt ccagtaaatt ccataaaaac actaattcag cgctataaca cctgaaaaaa
    47281 agggcgatga atctttatat attctgaata ttcacactct ttacaggaac tttttagagc
    47341 aataggccat caggagtata gtgatgcccg acagaagaag tgttctgaat gaaagcgact
    47401 aacttaagga gtgaggaaag atggaaagta atttcattga ctggcatccc gctgacatca
    47461 ttgcgggttt gcgcaagaag ggaacgtcaa tggcggcgga gtctcgcaga aatggtttga
    47521 gttcctcaac gctggcaaac gcattatcgc gcccatggcc gaaaggagag atgattattg
    47581 tgaaagccct gggaactgac ccctgggtta tctggccatc acgctaccat gatccgcaga
    47641 cccatgagtt tatcgacaga acgcagttga tgcgtagcta cactaaaccg aaaaaatgag
    47701 tggtctggcg gtagccccgc gaacggggct gccagctctc agacgattac tcgcctttca
    47761 cacgctcaat atttgcacct aaagcgcgca gtttgtcttc aatgcgttcg tagccacgat
    47821 cgatgtgata aatacgatca accaccgtcg tcccttccgc aatacagcca gccagcacca
    47881 ggcttgctga tgcacgcaga tcggttgcca taacctgtgc gccagaaagt ttttcaacac
    47941 cgtgacaaat aacggtattg ctttcgattt cggcatgcgc gcccatacgg ctaagctccg
    48001 gcacatgcat aaagcggttt tcaaagaccg tttcggtgat gaatccggtc ccttctgcca
    48061 ccaggttcaa cagcgtgaac tgggcctgca tatcggtcgg gaatgccgga tgcggcgcgg
    48121 tacgtacgtt aacagccttc ggacgtttgc catgcatatc caggctaatc cagtcttcgc
    48181 cgacttcgat gtccgctcca gcgtcacgca gtttcgccag cacggcgtcg agagtatctg
    48241 gctgcgcgtt acggcagata attttgccgc gagaaatcgc cgccgccacc aggaaagtac
    48301 cagtttcgat acgatccggt agcacgcgat agacaccgcc gcctaaacgt tccacacctt
    48361 cgatgacgat acgatcggtg ccctgaccgc taattttcgc acccagcgta atcaggaagt
    48421 tcgcggtatc gacgatttcc ggttcacgcg ctgcgttttc aataatcgtg gtaccttccg
    48481 ccagggttgc agcacacatg atggtcaccg ttgcgccaac gctgacttta tccatcacga
    48541 tatgtgcgcc tttcagacga ccatcgacgg aagctttaac gtaaccttct tccagtttga
    48601 tggtcgcgcc taattgttcg aggccagaaa tgtgtagatc aaccggacgc gcaccgatcg
    48661 tacaaccgcc aggcagtgaa acttgcccct gaccaaagcg cgctaccagc ggccccagtg
    48721 cccagataga agcacgcatg gttttaacca gatcgtaagg tgcgcagaat acattaacgt
    48781 cgcgggcatc aatatgcaca gaaccattac gttctacttt cgcacccagc tggcttagca
    48841 gcttcattga tgtatcgacg tctttcagtt tcgggacgtt ctggatctct accggttctt
    48901 ccgccagtag agcggcaaaa aggataggca gagcagcatt tttagcgccg gaaattgtga
    48961 cttcgccctg gagcttcgtt ggcccctgaa cacgaaattt atccatttag tttgttctca
    49021 gttaacaatt catatccgct accggcgaat cgcccatagc tcaaaagccg ttcagtttgc
    49081 gatcgcgcgc ccactccgca ggggtatacg ctttgatcga cacagcatga atgcggttat
    49141 ccgcaatata ttccatcagc gggccataga ccgtctgctg ttttttaacc cgactcatgc
    49201 cgtcaaacaa ctcacccacg gcaataacct gaaagtggct gccatcgccg gaaacgtgga
    49261 cttcctggag ggagagagcg ttcatcaaca cgctctgaat ttcattattt tccatgggat
    49321 cttcaatcat cagttaataa accagcgaaa catcttagag caaagttgcg ctggcataaa
    49381 taagcaaaaa gcctcgctga taaatcagac aaggctcgac ttgcaggcag gtttgccgga
    49441 caggcggtta acgccatatc cggcctgaaa aaatttaacg aggcagaaca tcagcaggca
    49501 aattatacaa tttcgcgagg gtatacactt tgtcgtttac cccctgaagc gtcacgttgt
    49561 tgccctgctt tttcgccaga tcgataagat ggagcagcag tgccagtcca cccgtatcca
    49621 cgcgggacac acggctaaga tcgatgcagg taatcccctt caccgcttcc tcacgcattt
    49681 cccaaagcgg tagcagaacg tcctgatcca gctctccgga taacgccagc gtgtcacccg
    49741 tctgcatcca gctcagtgac tcgctcatta ttttttctct tccagagtga ttttctgttg
    49801 agaaatcgat ttcagttgcg cagtcaggcc gtcgatacct ttggtacgca gcagcgttcc
    49861 ccactcgttt tgtttggtgg tgatcatact gacgccttca gcaatcatgt cgtaagcctg
    49921 ccagttgccc gtctgggagt ttttacgcca ctggaagtcc agacgcaccg gcggacggcc
    49981 attcgggtca ataatggtaa cgcgaatagg cacaatggtt ttatcgccca gcggctgttc
    50041 tggcgcaatc tgataggttt gaccgtgata catcgccagc gcctgaccgt aagcctgctt
    50101 caggtactca cggaaagcgg caaagtaggc ttcacgttga gcaggggtcg cactcttgta
    50161 atactggccc agcaccagcg caccggcgta tttcacctgt acgtatggca gcagttcctg
    50221 atcaacaatg gtacgcagat aatccgggtt ggcccgaatt tgcggttgct cattcttcag
    50281 gcgatcgaac gttttctgcg ccgcctcgtc catcagctta taaggattgg tctggtctgc
    50341 cgcggttgcc gcactcagag gtgcaatcac cagcaaagcg accatcatta aacgtttaaa
    50401 catgcgtcgg ttctcctgaa attatttcgt tgtacccaca ggttcagtgg tttcattatt
    50461 acctggcgca gcagctggcg catcgccact attcttattg tcatcgcctt tactaccgta
    50521 aaggaactga ccaatgagat cttccagcac catcgcagac ttagtgtcct gaattgtatc
    50581 gccatccttc aggatagcag tccccagttc cgggtcttca aaaccgacgt ttaatgccag
    50641 atattgttcc cccagcaggc cggaagtacg aatgctcagc gaactggtat ctggaatgtg
    50701 gttataacgt tgttcaattt ccagcgttac gcgcggcaga taggttttcg ggtccagcgt
    50761 aatatccgcc acccgaccca caacaacgcc accaatactg accggagagc gcgctttcag
    50821 gccgccaatg ttatcgaacg tcgcataaag cgtgtaggtc ggttcagtac gtatggacgt
    50881 cacgttcgcc gccttcaggc aaacaaacag cgccgccagc agtgctgcta ataaaaagat
    50941 acccacccaa atttcatttt ttttcgtttg catgaactca attcccaaac atcaatgcgg
    51001 tcagcacaaa atccagcccc agaacagcca gagacgagtg gacaacggtg cgagtggttg
    51061 cccggctaat cccggcagac gtcgggatgg cgtcgtagcc gttaaacaac gaaatccacg
    51121 tcaccgtgat ggcgaacacc acgctcttaa tcagacagtt gaccagatcc atacgccagt
    51181 cgacggcatt ttgcattgcc gaccagaaga acccgctatc aatgcctttc caactgacgc
    51241 cgaccagaga tccgccccag atccccacgg cgacgaaaat aaccgtcaac agtggtaatg
    51301 aaataacccc agcccagaaa cggggagaaa taacccgacg cagcggatcc accgccatca
    51361 tctccatact ggagagttgc tctgtagcgc gcatcaggcc gatttctgcg gttagcgccg
    51421 aaccagcacg cccggcaaac aacaacgcgg caaccaccgg ccccagttca cgcagtagcg
    51481 ataacgccac cagcataccc agactggttt ccgcactata agtggtcaga accagataac
    51541 cttgcagccc caacaccatt ccgatgaaca cgccagaaac cacaataatc agcatcgaca
    51601 ggacgccgac attatagagc tggcgcacca gcagcggcgc atgtttgcga aattccggtt
    51661 tgccgaccag cgcattgaat aacattaacc cggcccgccc gaacgttctc agggttttaa
    51721 tccctttatg tccgagcgac gccagcgcat ttaacagcat gagtggctta actccctggt
    51781 aaaagatcag cgtgataatc gccggcagga tagcggaacg gaacaggccc gtcagctatc
    51841 ccgtccagaa actgacgtac gcgcggatca ggattcgcct gcaacgcctg ggcactgcca
    51901 tgagcgacaa tttttttgtc cgccaggatc caggcgtgat ccgcaatact taacacttcc
    51961 ggcacatcgt gagaaaccac cacacaagtc acgcccagcg cgctgttcag ctcagaaatc
    52021 agcttcacca gtacgcccat ggtgatggga tcttgcccaa caaaaggttc atcaaacatg
    52081 atgagatccg gctccagcgc aatcgcacgc gccagcgctg cacgccgcgc catcccacca
    52141 gaaagttcag aaggcattag cttagccgct ccacgcagcc ccacggcctc cagcttcatc
    52201 atcactgtac tatgcaacaa tggcgcggga agttgggtat gttcgcgcag tggataggcg
    52261 acgttgtcaa atacgttcat atcagtgaac aacgccccgg actgaaataa catgctcatc
    52321 cgtttgcgca ctgtatacag gcgcgaacga gacatcgccg gaatattctc accatcgaaa
    52381 aggatctcac catgatctgg tgcgatttgc ccgccaatca gacggagtag cgtcgtttta
    52441 ccgatgcccg atggccccat gattgccgtg atcttccctc gcggcacggt cagggaaata
    52501 ttatcgaaga tgcagcgatt gccacgcgta aaactgacat cgcgcatatc gactaaattc
    52561 gccacagact gctccataat tcacccttcg tcttgcgttg attttctaag catggcgctc
    52621 aatttaacct tgaacccaac atatttacag aatattaccc gccgtggtta gcgaaagctg
    52681 gcatttgttt tactttttag ccgcataaag tcaaaattaa gaatccgtta cggctttctg
    52741 aaaatcttca gcggaccggc gagtatacct gaagaaagga cgttagatgc ttttagctac
    52801 ggcactgtta attgttggtt tacttttggt cgtttacagt gccgaccgcc tggtttttgc
    52861 cgcgtctatt ctttgccgaa cctttggcat cccgccgctg atcatcggca tgacggtggt
    52921 cagtattggt acatcgttac cagaaatcat cgtctcgctt gccgcgtctc tgcacgaaca
    52981 acgcgattta gccgttggta cagccctcgg ctcaaacatt atcaatatat tgctgatcct
    53041 cggtctggct gcgctggttc gtccttttac cgtccattct gatgttctac gccgtgaatt
    53101 acccttaatg ttgttggtca gcgtggtggc cggttccgta ctctatgacg gacaacttag
    53161 tcgcagcgat ggtatctttc tcctctttct ggctgtgcta tggctgctgt tcattgttaa
    53221 acttgcacgt caggctgaac gtcaggggac tgacagcctg accagagagc agcttgcaga
    53281 gctgccgcgt gacggcggat tgcccgtcgc gtttttatgg ctcggcattg cgcttatcat
    53341 catgccagtg gccacgcgga tggtggttga taacgccacg gtgctggcga attactttgc
    53401 catcagcgag ttgacgatgg ggctgacggc aattgctatc ggaaccagcc tgccggaact
    53461 ggcaaccgca atagcggggg ttcgcaaagg tgaaaacgac attgctgtcg gaaatatcat
    53521 tggcgcaaac atttttaata ttgtcatcgt gttgggttta cccgcgctga taacgccagg
    53581 agagattgat ccactggcgt acagtcgtga ctacagcgtg atgttgctgg tgagcattat
    53641 ttttgcgttg ctgtgctggc ggcgctcccc gcaaccgggc cgtggtgtag gggtattatt
    53701 aactggcgga tttatcgtat ggctggcgat gttgtactgg ttatcgccaa tactcgttga
    53761 ataactggaa acgcattatg tcgcacgtag agttacaacc gggttttgac tttcagcaag
    53821 caggtaaaga agtcctggcg attgaacgtg aatgcctggc ggagcttgag caatacatca
    53881 atcagaattt cacgcttgct tgtgaaaaga tgttctggtg taaagggaaa gttgtcgtca
    53941 tggggatggg gaaatcgggg cacatcgggc gcaaaatggc ggcaacgttt gccagcaccg
    54001 gtacaccttc atttttcgtc catcctggtg aagccgcgca tggtgattta ggcatggtta
    54061 ccccacagga tgtggtgatt gctatctcta actcaggtga atccagcgaa atcacggcct
    54121 taattccagt gcttaagcgt cttcacgtac cgttaatctg catcaccggt cgcccggaga
    54181 gcagcatggc gcgcgccgca gatgtgcatc tgtgtgttaa agtagcgaaa gaagcctgtc
    54241 cgttagggct ggcaccgacc agcagcacca ccgccacgct ggttatgggc gatgccctcg
    54301 ctgtcgcgct gttaaaagca cgcggcttta ctgctgaaga ttttgcgctc tcacacccag
    54361 gcggcgcact gggtcgtaaa cttctgctgc gcgtaaacga tattatgcat acgggcgatg
    54421 agatcccgca tgttaagaaa acggccagtc tgcgtgacgc attgctggaa gttacccgca
    54481 aaaatcttgg tatgactgtc atttgcgatg acaatatgat gattgaaggc atctttaccg
    54541 acggtgattt acgccgtgtc ttcgatatgg gcgtggatgt tcgtcagtta agtattgccg
    54601 atgtgatgac gccgggggga atacgtgtgc gccctggcat tctggccgtt gaggcactga
    54661 acttaatgca gtcccgccat atcacctccg tgatggttgc cgatggcgac catttactcg
    54721 gtgtgttaca tatgcatgat ttactgcgtg caggcgtagt gtaaagattc aaggataaac
    54781 aacaatgagc aaagcaggtg cgtcgcttgc gacctgttac ggccctgtca gcgccgacgt
    54841 tatggcaaaa gcagagaaca ttcgtctgct gatcctcgac gttgatggcg tactgtcaga
    54901 tggcctgatt tatatgggca ataacggcga agagctgaaa gcgttcaatg ttcgtgacgg
    54961 ttatggcatt cgttgtgcgc tcacctctga tattgaagtc gctatcatta ccgggcgaaa
    55021 ggctaaactg gtagaagatc gttgtgccac attggggatc actcacttgt atcaggggca
    55081 gtcaaacaaa ctgatcgcct ttagcgattt gctggaaaaa ctggcgattg ccccggaaaa
    55141 tgtggcttat gtcggcgatg atctcatcga ctggccggta atggaaaaag tgggtttaag
    55201 cgtcgccgtg gccgatgcgc atccactgtt gatcccgcgc gccgattacg tgacgcgcat
    55261 tgctggcggt cgtggcgcag tgcgcgaagt ttgcgactta ttactcctgg cgcagggcaa
    55321 actggatgaa gccaaagggc aatcgatatg agtaaagcca gacgttgggt tatcattgtg
    55381 ctatcactgg cggttctggt gatgatcggc attaatatgg ccgaaaaaga cgataccgcc
    55441 caggtggtcg tcaacaacaa tgatcccacc tataaaagcg agcatacgga cacgctcgtc
    55501 tataacccag aaggggcact aagctatcga ttgattgctc aacacgttga atattattcc
    55561 gatcaggccg tttcgtggtt tacgcagccg gtacttacca cgtttgataa ggataaaatc
    55621 ccgacatggt ccgtaaaagc agataaagcc aagctgacca atgaccggat gctctattta
    55681 tatggacacg ttgaagtcaa cgcactcgtg ccggactctc aacttcgcag aatcacgacg
    55741 gataacgcgc agatcaatct ggtgacgcag gatgttacct ctgaagacct cgtcacgtta
    55801 tacggaacaa catttaactc cagcggtctg aaaatgcgcg gcaacttacg cagcaagaac
    55861 gccgagctga ttgaaaaggt tagaacatcc tatgaaattc aaaacaaaca aactcagcct
    55921 taatcttgtg cttgccagct cacttctggc cgccagcatt ccggcatttg ccgtaaccgg
    55981 agacactgat cagccgatcc acattgaatc ggaccagcaa tctcttgata tgcaaggcaa
    56041 cgtggttacc tttaccggta atgtcatcgt cacccagggc accatcaaaa ttaatgccga
    56101 caaagtggtt gttacccgtc cgggcggcga acaaggtaaa gaagtgattg acggctacgg
    56161 taaaccggca acgttctacc agatgcagga caacggtaaa ccggttgaag gtcacgcttc
    56221 ccagatgcac tacgaactgg caaaagattt tgtcgttctg acgggtaatg cttatctgca
    56281 gcaggttgat agcaacatta agggcgataa gatcacttac ctggtaaaag agcagaaaat
    56341 gcaggctttc agcgacaaag gcaagcgcgt aaccaccgtt ctggtgccgt cgcagctgca
    56401 ggacaaaaac aacaaaggcc agaccccggc acagaagaag ggtaattaat tcgttatggc
    56461 aacattaact gcaaagaacc ttgcaaaagc ctataaaggc cgtcgcgtgg tagaagacgt
    56521 cagcctgacc gtcaactccg gggaaattgt cggtctgctg gggccaaacg gtgccggtaa
    56581 gaccaccact ttctacatgg ttgtaggcat tgtgccgcgc gatgcgggca acatcattat
    56641 tgatgatgac gatatcagtc tgctgcctct gcatgcacgc gcgcgccgcg gtatcggcta
    56701 tctgccacag gaagcctcca ttttccgtcg cctcagcgtt tacgataacc tgatggcggt
    56761 actgcaaatt cgtgacgact tgtctgctga acaacgtgaa gaccgcgcga acgagctgat
    56821 ggaagagttt cacattgagc acctgcgtga cagcatgggg cagtcactct ccgggggtga
    56881 acgtcgccgt gtagaaattg cccgcgcact ggctgcgaat ccgaaattta ttctgctcga
    56941 cgaaccgttt gccggggttg acccgatctc ggttatcgac attaaacgca tcattgagca
    57001 cctgcgcgac agcggcctgg gcgtgctgat cactgaccac aacgtgcgtg aaacactggc
    57061 ggtttgtgaa cgcgcttata tcgtcagtca ggggcatttg atcgcccacg gcacgcctac
    57121 agaaatctta caagacgaac acgttaagcg tgtatacctt ggggaagact tcagactctg
    57181 atagggtaga agtttgcgac gttttagcag gagagtacga ttctgaacat gaagcaaggt
    57241 ttgcaactca ggcttagcca acaactggcg atgacgccac agctccaaca ggcaattcgt
    57301 ctgttgcagt tgtcgacgct ggaacttcag caggagctac agcaggcgct ggagagtaat
    57361 ccgctgcttg agcaaatcga cactcatgaa gaaatcgaca cccgcgaaac gcaagacagt
    57421 gaaacgctgg acaccgccga cgcgctcgaa caaaaagaga tgccggaaga gctgccgctc
    57481 gatgccagtt gggacaccat ttacaccgct ggtacaccat ccggcaccag cggtgactac
    57541 attgacgatg agctgccggt ctatcagggc gaaacgacgc agaccttgca ggattacctg
    57601 atgtggcagg tcgagctgac accgttttcc gacactgacc gcgctattgc tacctctatc
    57661 gtcgatgccg ttgatgacac cggttatctg actgtcccgc tggaagatat tctcgaaagt
    57721 atgggcgatg aagagatcga catcgacgag gttgaagccg tccttaagcg gatccaacgg
    57781 tttgatccgg tcggtgtagc ggcaaaagat ctgcgtgact gcctgctaat ccaactctcc
    57841 caattcgata aaaccacgcc gtggctggaa gaggccagac tgatcattag cgatcatctc
    57901 gatctgttag ccaatcacga cttccgcact ttaatgcgcg tcacgcgtct gaaagaagat
    57961 gtgctgaaag aagccgtcaa tctgatccag tcgctcgatc cgcgccccgg gcagtcgatc
    58021 cagactggcg aacctgagta tgtcattcca gatgtgctgg tgcgtaagca taacggtcac
    58081 tggacggtag aactcaacag tgacagcatt ccgcgtctgc aaatcaacca gcactacgcc
    58141 tcgatgtgca ataacgcgcg caacgatgat gacagccagt ttatccgcag caatctgcag
    58201 gatgccaaat ggttgatcaa gagtctggaa agccgtaacg atacgctact gcgcgtgagt
    58261 cgctgtatcg ttgaacagca gcaagccttc tttgagcaag gtgaagaata tatgaaaccg
    58321 atggtactgg ccgatatcgc ccaggctgtc gaaatgcatg aatcgacgat atctcgcgtg
    58381 accacgcaaa aatacctgca tagtccacga ggcatttttg aactgaagta tttcttttcc
    58441 agtcacgtca ataccgaggg cggcggcgaa gcttcctcca cggcgattcg tgcactggtg
    58501 aagaaattaa tcgcggcgga aaacccagcg aaaccgttga gcgacagcaa gttaacctct
    58561 ttactgtcgg aacaaggtat catggtggca cgccgcactg ttgcgaagta ccgagagtct
    58621 ttatccattc cgccgtcaaa ccagcgtaaa cagctcgttt gacccaaccg ataaggaaga
    58681 cactatgcag ctcaacatta ccggaaataa cgtcgagatc accgaggcac tgcgcgaatt
    58741 tgttacagct aaatttgcca aacttgagca atattttgac cgaatcaacc aggtctatgt
    58801 tgttctgaaa gtggagaaag tcacccacac ctcagatgca acactgcatg taaacggtgg
    58861 tgaaattcat gccagcgcgg aaggtcagga catgtacgct gccattgatg gcttaattga
    58921 taagctggca cgccagttga ccaaacataa agataaactg aaacaacact aattgtccgg
    58981 gcaattagca tgtgcatggc ggcctgttgt gcggcacaac gggccatttg tacggttaat
    59041 gctccgagcc tgttccactg tttgagtggg caggttctta ggtgaaatta tgacaaataa
    59101 tgatacaact ctacagctta gcagtgttct taacagggaa tgtacgcgaa gccgcgtcca
    59161 ctgtcagagc aaaaaacgcg ccctggaaat catcagcgag ctggcggcga aacaacttag
    59221 cctgccgcct caggtggttt ttgaagctat cctgacgcgg gaaaaaatgg gcagtaccgg
    59281 tatcggcaat ggtattgcca ttccgcatgg caaactggaa gaagatactc tgcgcgccgt
    59341 tggcgttttc gttcagctcg aagcgcctat agctttcgat gccatcgaca accaaccggt
    59401 ggacttactt tttgccctgc tggtgccggc agaccaaact aaaacgcacc tgcatactct
    59461 gtcgctggtg gcgaaacgtc tggcggacaa aaccatctgc cgccgtttac gcgcagccca
    59521 gagcgatgaa gagctgtatc aaatcattac ggataccgaa ggtactccgg atgaagcgta
    59581 gttattcggt aatgtctctt ttagacgttg tgaggagaaa cagtacatgg tactgatgat
    59641 cgtcagcgga cgttcaggtt caggtaaatc tgtcgccctg cgtgcgctgg aagatatggg
    59701 tttttactgc gtggataacc ttcccgtagt gttgttaccc gatctggctc gaactctggc
    59761 cgatcgcgag atttctgccg ccgtcagcat tgatgttcgt aatatgccgg agtcaccaga
    59821 aatattcgaa caggcgatga gtaacctgcc tgacgctttc tcaccgcaac tactgttcct
    59881 ggatgccgac cgtaatacct taattcgtcg ttacagtgac acgcgccgac tgcatccgct
    59941 ttccagcaaa aacctgtcgc tggaaagtgc tatcgacaaa gaaagcgatt tgctggagcc
    60001 tctgcgttcg cgagcggatc tgattgtcga tacctcagaa atgtccgttc acgagctggc
    60061 tgaaatgctg cgtacccgtc tgctgggtaa acgtgaacgc gaactgacca tggtctttga
    60121 gtctttcggc ttcaaacacg gtatccctat cgatgcagat tacgtctttg acgtgcgctt
    60181 cttgccgaac ccgcactggg atccgaaact gcgtccaatg acaggtcttg ataaacctgt
    60241 cgccgcgttc ctcgaccgcc acacagaagt acacaatttt atctaccaga cgcgaagcta
    60301 tcttgaacta tggttaccta tgctggaaac caacaaccgt agctacttga cggtcgccat
    60361 tggttgtacc ggcgggaagc accgttcggt gtatattgca gagcaactgg cagactactt
    60421 ccgctcgcgc ggtaaaaacg tccagtcacg ccatcgtacg ctggaaaaac gtaaaccatg
    60481 accgtcaagc aaactgttga aatcacaaac aagctgggca tgcatgcccg gcctgcaatg
    60541 aagctgtttg aattaatgca gggttttgac gctgaagtgc tgttacgtaa tgacgaaggc
    60601 accgaggccg aagccaacag cgttattgcg ctgctgatgt tggattctgc caaaggacgg
    60661 cagattgaag ttgaagcgac cggcccacag gaagaggaag cactggccgc cgttatcgcc
    60721 ctctttaact ctggttttga tgaagattaa tcttcatcac tttgacatac aactcccttc
    60781 aaactccccc cgacaataag aaaatcacgt actgaaatcg ttctcaatca acgtcatttg
    60841 tacattttgt gcgcttttca ctttcagaag aaccttaaga aaaccttaag aggcattgtt
    60901 taggttttgt ttaagttaat cgaccatact ggagatcgtc agaaaatatt tccaggagat
    60961 ggcatgattc gcttatctga acaaagtccc ctgggcaccg gaagacatcg gaaatgttat
    61021 gcgcatccgg aagatgccca acgctgtatc aagattgtct accatcgtgg cgatggtggc
    61081 gataaagaga tccgccgtga gttaaagtac tacgcgcatc ttggtcgccg gttaaaagac
    61141 tggagtggaa taccgcgcta tcacggtacc gttgagacgg attgcggaac cggttatgtc
    61201 tacgatgtga ttgcagattt tgacggtaaa ccctccatta cgctgaccga atttgctgaa
    61261 caatgccgtt acgaagaaga cattgcacaa ctgcgccagc tactgaaaca gctgaagcgt
    61321 tatttgcagg ataaccgtat cgtgacgatg tcgctgaagc cgcagaatat cctctgtcac
    61381 cgcatcagtg agtcagaggt tatcccggtc gtctgtgaca acattggtga aagcacattg
    61441 attccactgg cgacctggtc gaagtggtgt tgtctgcgta agcaagagcg gttatggaaa
    61501 cgatttatcg cccaaccggc gctggctatt gccctgcaga aagatctgca acctcgtgag
    61561 agcaaaacgc tggccctcac ttcgcgcgaa gcttaatcca gctggtgttg ttgcataaac
    61621 ggctcaccgc ctaactgata catctgccgt aaaatccacg cctgacggct acgcacgtag
    61681 cccgatggcg aggagacttt gaaacgaagt ggattaggta atacagctgc cagtaatgca
    61741 gcttccgacc gggtaagttt gctcgcgggt ttgtggaaat aacgttgtgc cgcagcttcg
    61801 acgccaaaca caccgtcgcc aaattcggcg atattcaggt aaaccgtcag gatacgcttt
    61861 ttgctccaga ctgtttctat ccccagcgtt aatccagctt ccagcccttt tcgtacccag
    61921 ctacgcccat cccataaaaa gagatttttg gccgtctgct gagaaatcgt tgaagcaccg
    61981 cgaatacggt tttcattgcg ctcgttgtgc gccagggctt tctcaatgga agcgacatca
    62041 aagccccagt gctcaggaaa tttctgatct tctgcggcaa tcaccgccag tcccatccac
    62101 ggcgagattt gatccatact gacccagtca gaatgtgcca cgtaacgaaa attgccatgc
    62161 agccaggcgc tgacctgtcg ctcgaccatt accgctgaga agggaacagg cgcaacacta
    62221 aacaacgcga tgcccccgcc ccagaaaacg gcgaggacaa ccattaaccg caaaagaaaa
    62281 cggcgaacga aactaaacac cgttaagcgg cttttactca ttcagccaga accagcacgc
    62341 gggaaaccag cttatcaatg ccgctcgccg cttctgcaat gttctgcgcc agcatatatg
    62401 ctggggtggt gacaatctta ttgtcttcat caaccacgat atcatcgaca ggacagggca
    62461 catgctccgc gcccatctct tccagcactt ctgcggtatc gatatcagta ccgatggtca
    62521 aacgcagcgg gaaatcgaaa attttcggca gcatcgccgg ggcaatacac ataaaaccaa
    62581 gcggttttcc ggcctgatgc atcgcttgtg ccagcgcctt taattcacgg tcaacggtgc
    62641 attcgctacc aagagtggca aaattgctta aattcttcgc cgcgccaaac ccccccggca
    62701 caatcaacgc atccagttca gcggcatcgg cctgggccag aggacggatt tcaccgcgcg
    62761 ttattcgtgc cgcttcaatc agcacgttgc gcgtttccgt catcgcttcg ccagttaaat
    62821 ggttgataac atcaacctgc tgcttatccg gtgcaaagca gaccgcctgc gcaccgctgc
    62881 gtgaaatagc taacaacgtc aacaccgctt catgaatttc agaaccgtca tagacgccgc
    62941 atccgctcag aattacgcca attttcttca ttgtgatcat cctttcgcaa ttgactgaaa
    63001 cacattaatt tttttaataa aaatggtacg catcacacat ttaactgatt catgtaacaa
    63061 atcatttaag ttttgctatc ttaactgcgt gcggcctgaa aaacagtgct gtgcccttgt
    63121 aactcatcat aataatttac ggcgcagcca agatttccct ggtgttggcg cagtattcgc
    63181 gcaccccggt ctagccgggg tcatttttta gtggcttttg ccacccacgc tttcagcact
    63241 tctacgtcgt gacgccactc ttctttcatc tcttcaatcc attcaccgac gttatcttcc
    63301 caggcaggaa ggtccggaga ctgaatttgc tgacccagct gttgcagatg gcgtaacccc
    63361 actgaccccg ccgcaccttt aattttatgt ccttcctcta caatgccttt tttatcctgc
    63421 gccgtcagat tcgactccag cacgctgaca tagcccggca tcatcttctc aaacaccgct
    63481 aacccgtcgg tgatcagctt cggtcctaca agttcgagat actgttccag catgggaata
    63541 tcgagcaatg cttctgattt actgttctct tctgtcgtca ccgtactctc ctcatcatcc
    63601 tgggtatccc agaatttctt gatcatcgcg gttagcgccg gaaccgaaag cggcttactc
    63661 agcacatcat ccattccagc attgaggtac tcttgtttgt ctttcagcac gttagcggtt
    63721 aaggccacca gcggcggtaa atcctcgcgc ggataacgct tcgtcagttc acgagagata
    63781 tccagcccgg tcatatctgg caactgaata tccagcaaca ccaggtcgta ttcgcccggt
    63841 ttaaacatct ccagcgccgc cttgccggtc atggcgacat caacgctgtt acctaatttt
    63901 tccagcacag aacgcgcaac aatcacgttc agttcaatgt cttccaccag cagcacattc
    63961 agcgccggta aaggcatatc gtcttcatca aacgcatcat cgacctcttc tgctaccgac
    64021 ggtgcgtgga tcgtcaacgt aaaggttgaa cctttgccct gttcgctggt aaccgtaata
    64081 tcgccgccca tatttttcgc cagacgacga gaaacggcca gaccaatacc ggtgccggtg
    64141 gcaggtttac cgccatgact gtctttcacc tggtaataca tggcgaaaat tttatccagc
    64201 tcatcctgcg gaatgccgat accagagtct tccacttcaa aatgcagcat atcgccttca
    64261 tcgtagcgca cgcgcacggt aacctggcct tgctgggtga atttgacggc gttactgatg
    64321 aggttccaca ggatctgccg taaacgcgtc ccgtcggtaa tgacctgatg cggtaatggc
    64381 agcgtcggct ccaggttaaa gcacaatcct ttttgttgcg cctgcaatgc ggagagattt
    64441 tccagatcgg caaggaagct ggtgaaatca accggttgat tatcaagctg gaccttgcgc
    64501 cgttccatct tatccatgtc gataatatcg ttaaagatat tccccagcgt gacggccgaa
    64561 acatggatgg tcttgagata tttttcctgc tcggcggtga gttcggtatc cagcagaata
    64621 cggctcaggc cgacgatacc gttcagcggt gtacgcaatt cgtgactgat ggtggaaata
    64681 aacgtcgttt tgtcgcggct ggcccgttca agcgcatcct gataccgctt acgctcggta
    64741 atgtcgcgac caaagcccat caaaccgtga cgtttaccca cgcggtcgta gtacggcact
    64801 ttacggattt caaagcaggc tttgcgcccg tccgggtaat ccagccactg ttcataggtc
    64861 agtgacacat tatgacggaa cactttttca tcggtttcaa tgacttttgc ggcggcttcc
    64921 ggtgagtaaa catcagcagg tttcaggtga accagttgtt tttcgctttt tccggtcagc
    64981 agctccatcg cgcggttaca gccggaaaac tctttatctt cgttacgata aaaaaccagg
    65041 tcgggtgaag catcaaggaa ggaacgtaag aatgaggatt gctgctcgag ctgaatttgt
    65101 gtctcttcgc gctctttgat ttcaattttc agttggccga aggtttcctg cagttctgct
    65161 tccgcttttt cacgaacggc aatttcctga tttagctggg caatattatc ttttaactga
    65221 acgttgaggc tcaaatcgcg ctcgcgcatc tcctccagtt tttgcaccag ccgtgacaga
    65281 cgttgtcgtg actcctccag ttgctcgacg accaccgata gaaagtagac cgcccacggc
    65341 gtaatcagca aaccaaagaa gatagaacga ataacatcaa tgctttcgac ctgaccatgc
    65401 agcaccatgg ttaccgccat ttgtaccaca atggcaagaa cgacgagggc cagcgccagc
    65461 aacattgaga agcgcaccag acctaacttc atcatcaggt caacataata ctgcgccagc
    65521 agacgaattt gcttcattag ggaattcctt cacgacaacc tgccccaata atacccaatt
    65581 ctgacagtta cgttataaat tgtgtgagaa atgcggaatt cccctcaacg acctactccg
    65641 ttggaggtat ccacggacgt tccagcgccg atccctgtac gccatgttca ttcagatagc
    65701 gatccagctc gaccattccc gtccatcgat tttcgcacca cagaggagca agcagcgtcg
    65761 ggcgacgggc gctggcggaa atgcggtggt agatcacttc cggtggcgta tggcgaatca
    65821 tttctccggc agtgagcgtg taatcctcca gttcaatacc gttcaaacgc cccgcttccc
    65881 aggctttcgc cataatgctg cctttcacaa tatgcagcgg atgcagcttt atgccgtcca
    65941 cgccggtttc aaccactcgc tccagcgttt gcaaacattc agcctgccct tcgccaggca
    66001 ggccgacaat taagtgggaa cacaccttca gcccgcgctg acgtgccagc tgggttgtac
    66061 gctgataaca ggcaaaatca tggccgcggt tgatgcgatg cagtgttttg tcgtgggcgg
    66121 tttgtagccc cagctccagc cacacttcgt aaccctggtc cttatattcg caaagcagat
    66181 ccagcaccgc atccggcacg cagtccgggc gggtaccaac acacaaaccg acaatattgg
    66241 cctggctcac cgcctgctga tacatagaac gcagcacctg aacttccgca aaggtgctgg
    66301 tatacgcctg aaagtaggcc agatagcgtt tagcgcggtt aactaaattc gcctggtgcg
    66361 ccagttgctc ggcaatggaa cgatgctgct gcgcttcatc ggcaaacgag gcaacattac
    66421 agaatgtgca gccaccacgc ccgatggtac cgtcacggtt agggcagcta aaaccgccgt
    66481 gtagcgtcag cttatgcacc ttttgcccat aacgacgggt gagatcacca ccaaacatat
    66541 tgactaattt ctgtaactgc ataatctgat agaccgcgcc ttgaaaagag gccaaagcct
    66601 gccattttta gctcaattcg gcgatgacct ggatcaatcg tcccggcctg cttttatcaa
    66661 ctgcataatc aatcaaaatt accgaaattt catgcataat cacataaatc acttttgctt
    66721 atcttgtgtc agattttttt atctccttat ggattttagg caaaaacagt agcatgaaac
    66781 gtcattacca attaaggcag tataaaatgc tggttttctc gtcagttcaa ggcaggataa
    66841 gggttaacac gcctttatga cagtcaggaa ttgactgttt ctctaacgac ttccctttta
    66901 gccttaaaga taaaatccat tttaatttca gtaatttaat aaagaatttt gcgctaaagc
    66961 acatttctgt accaataagc ttgccatttg acctgtatca gctttcccga taagttggaa
    67021 atccgctgga agctttctgg atgagcagcc tgctcatcat atttatgcag taattgagat
    67081 cccctcttca ccgtattaac cgatgcgaaa aggacaacaa gggggcgaat gcgaggcgcg
    67141 cgtatgacac gcaaaccccg tcgccacgct ctttctgtgc ccgtgcgcag cggttcggaa
    67201 gtggggttcc cgcagagcct gggggaggtt cacgatatgt tgtacgataa atcccttgag
    67261 agggataact gtggtttcgg cctgatcgcc cacatagaag gcgaacctag ccacaaggta
    67321 gtgcgtactg caatacacgc actggcccgc atgcagcacc gtggcgcgat tctcgccgat
    67381 ggtaaaaccg gcgacggttg cggcttgctg ttacaaaaac cggatcgctt ttttcgcatc
    67441 gttgcgcagg agcgcggctg gcgtttagca aaaaactacg ccgtcgggat gctattcctg
    67501 aataaagatc ctgaactcgc cgctgccgca cgccgcatcg ttgaagaaga actgcaacgc
    67561 gaaaccttgt cgattgtggg ctggcgtgat gtccccacta acgaaggcgt gctgggtgaa
    67621 atcgccctct cctctctgcc acgcattgag caaatttttg tgaacgcccc ggcaggctgg
    67681 cgtccgcgcg atatggagcg ccgtctgttt atcgcccgcc gccgcattga aaagcgtctc
    67741 gaagccgaca aagacttcta cgtctgtagc ctgtcgaatc tggtgaacat ctataaaggt
    67801 ctgtgtatgc cggcggatct gccgcgcttt tatctggatc ttgcggacct gcgtctggaa
    67861 tcggccatct gcctgttcca ccagcgcttc tccactaaca ccgtaccgcg ctggccgctg
    67921 gcgcagccgt tccgctacct ggcgcataac ggtgaaatca acaccatcac cggtaaccgc
    67981 caatgggcgc gtgcgcgtac ctataaattc cagacgccgc ttatccctga tctgcacgac
    68041 gccgcaccgt tcgtcaatga aaccggctct gactccagtt cgatggataa catgctggaa
    68101 ctgctgctgg caggcggaat ggatatcatc cgcgccatgc gtctgttagt gccacccgcc
    68161 tggcagaaca acccggatat ggacccggaa ctgcgtgcct tctttgactt taactccatg
    68221 catatggagc cgtgggatgg cccggcgggc atcgtgatgt ccgacggtcg ttttgccgcc
    68281 tgtaacctcg accgtaacgg tctgcgtccg gcgcgctacg tcatcaccaa agataagctc
    68341 atcacctgcg cctctgaagt cggtatctgg gattaccagc ctgacgaagt ggtcgaaaaa
    68401 ggccgcgtcg ggccaggcga actgatggtt atcgacaccc gcagtgggcg tattctgcac
    68461 tcggcagaaa ccgatgacga tctgaaaagc cgccatccat ataaagagtg gatggagaaa
    68521 aacgtccgcc gactggtacc gtttgaagat ctgcccgatg aagaagtggg tagccgcgaa
    68581 ctggacgacg acacgctcgc cagctatcag aaacagttta actacagcgc ggaagagctg
    68641 gactccgtaa ttcgcgtact gggcgaaaac ggtcaggaag cggtcggttc gatgggcgac
    68701 gacaccccat tcgccgtgct ctccagtcag ccgcgcatta tttacgacta cttccgccag
    68761 cagtttgccc aggtgactaa cccgccaatc gacccgctgc gtgaagcgca tgttatgtcg
    68821 ctcgccacca gtatcggtcg tgaaatgaac gtcttttgcg aagcagaggg ccaggcgcac
    68881 cgtttaagct ttaaatcgcc gattctgctc tactccgatt tcaaacagct cacgacgatg
    68941 aaagaggagc actaccgcgc agatacgctg gatatcacct ttgacgtcac taaaaccacg
    69001 ctcgaagcga cagtcaaaga gctgtgcgac aaagccgaaa aaatggtacg tagcggcacc
    69061 gtgctgctgg tgctctccga ccggaatatc gctaaagatc gcctgccggt tccagccccg
    69121 atggcggttg gcgcgatcca gacccgtctg gtcgatcaaa gcctgcgttg cgatgccaac
    69181 atcatcgtcg aaaccgccag cgcccgcgat ccgcaccact tcgccgtgtt gctgggcttc
    69241 ggcgcgacgg ctatttatcc ataccttgcc tatgaaacgc tgggccgcct ggtagacacc
    69301 catgcgattg ccaaagatta tcgtaccgtg atgctcaact accgtaacgg catcaacaaa
    69361 ggcttgtaca aaatcatgtc caaaatgggc atctccacca tcgcctctta ccgctgctcg
    69421 aaactgtttg aagcggtcgg tctgcacgat gatgtagtgg gcctgtgctt ccagggggcg
    69481 gtcagccgca ttggtggggc gagctttgaa gacttccagc aggatctgct gaacctgtcg
    69541 aaacgtgcct ggctggcgcg taagcccatc agccagggcg gcctgctgaa atacgtccac
    69601 ggcggcgaat accacgctta caacccggac gtggtgcgca cgctgcaaca ggcggtacaa
    69661 agcggcgagt acagcgacta tcaggaatac gcgaagctgg ttaatgagcg tccggcaacc
    69721 acgctgcgcg atctgctggc aattacgccg ggtgaaaacg cggtcaacat tgctgatgtt
    69781 gaaccggcaa gcgaactgtt taaacgcttt gataccgccg cgatgtctat cggcgcgtta
    69841 agcccggaag cccacgaggc gctggcggaa gcgatgaata gcatcggcgg taactcgaac
    69901 tccggtgaag gcggcgaaga cccggcgcgc tatggcacta acaaagtgtc gcgcatcaag
    69961 caggtggctt ctggtcgctt cggcgttact ccggcgtatc tggtcaatgc cgacgtcatt
    70021 cagattaaag tcgcccaggg cgcgaagccg ggcgaaggcg gtcagttgcc gggcgacaaa
    70081 gtcactcctt acatcgccaa actgcgctat tcggtgcccg gagtgacgct gatctccccg
    70141 ccgccgcacc acgatatcta ctctatcgag gacttagcgc agctcatttt cgacctcaag
    70201 caggttaacc cgaaagcgat gatctccgtg aagctggttt ccgaaccggg cgtaggcacc
    70261 atcgcgactg gcgtggcaaa agcttatgcc gatttaatca ccatcgcagg ctatgacggt
    70321 ggcaccggcg caagcccgct gtcgtcagtg aaatacgcag gttgcccgtg ggagctgggg
    70381 cttgttgaaa cccagcaggc gctggttgcc aatggtctgc gtcataagat ccgtttgcag
    70441 gtcgatggcg gcctgaaaac cggtgttgat atcatcaaag cggcgattct cggcgcagaa
    70501 agcttcggct tcggcactgg cccgatggtg gcgctcggct gtaaatatct acgtatttgc
    70561 catctgaaca actgcgcaac gggtgtagca actcaggatg acaaactgcg taagaaccac
    70621 tatcacggcc tgccgttcaa ggttaccaat tactttgaat ttattgcccg tgaaacccgc
    70681 gagctgatgg cacagctggg cgtaacgcgt ctggtggatc tgattggtcg caccgacctg
    70741 ctgaaagaac tggacggttt caccgccaaa cagcaaaaac tggcgctgtc gaagctgctg
    70801 gagaccgccg aaccgcatcc aggtaaggca ctctactgca ccgaaaacaa cccaccgttt
    70861 gataacggcc tgctgaacgc gcagttgctg caacaggcga aaccgtttgt cgatgaacgc
    70921 cagagcaaaa ccttctggtt cgatattcgc aacaccgacc gttctgtcgg cgcgtcgctt
    70981 tcaggctata tcgcccagac gcacggcgat caggggctgg cagccgatcc tatcaaagcg
    71041 tacttcaacg gcaccgcagg ccagagtttc ggtgtgtgga acgcgggcgg cgtggaactg
    71101 tacctgaccg gggatgccaa cgactatgtc ggtaaaggca tggcgggcgg cttaatcgcc
    71161 attcgtcctc cggttggttc cgccttccgc agccatgaag caagtattat cggcaacacc
    71221 tgcctgtatg gcgcgaccgg tggtcgtctg tatgccgcag gccgcgcggg tgaacgtttc
    71281 ggcgtgcgga actccggtgc tatcaccgtg gtagaaggca ttggcgacaa cggctgtgaa
    71341 tatatgacgg gcggtattgt ctgtattctg ggtaaaaccg gcgttaactt cggtgcgggc
    71401 atgaccggcg gcttcgctta cgttctcgat gaaagcggtg atttccgcaa acgcgttaac
    71461 ccggaactgg tcgaggtctt aagcgttgac gatctggcga tccatgaaga gcatctgcgc
    71521 ggtcttatca ccgagcatgt tcagcatact ggctctcagc gcggtgaaga gattctggcg
    71581 aactggtcaa ccttcgccac taaatttgcg ctggttaaac cgaagtccag tgatgtaaaa
    71641 gcactgctgg gtcatcgtag tcgtagcgca gcagagttgc gcgtgcaggc gcagtaaggg
    71701 gtagcaacaa tgagtcagaa tgtttatcaa tttatcgacc tgcagcgcgt tgatccgcca
    71761 aagaaaccgc tgaagatccg caaaattgag tttgttgaaa tttacgagcc gttttccgaa
    71821 ggccaggcca aagcgcaggc tgaccgctgc ctgtcgtgcg gcaacccata ctgcgagtgg
    71881 aaatgtccgg tacacaacta catcccgaac tggctgaagc tcgccaacga ggggcgtatt
    71941 tttgaagcgg cggaactgtc gcaccagacc aacaccctgc cggaagtttg cggacgagtc
    72001 tgcccgcaag accgtctgtg cgaaggttcc tgcactctga acgatgagtt tggcgcggtg
    72061 accatcggca acattgagcg ttatatcaat gataaagcgt tcgaaatggg ctggcgtccg
    72121 gatatgtccg gcgtgaagca aaccggtaaa aaagtggcga ttatcggcgc aggcccggca
    72181 ggtctggcgt gtgcggatgt cctgacgcgt aacggcgtaa aagccgttgt cttcgaccgt
    72241 catccagaaa ttggcgggct gctgaccttc ggtattccgg ccttcaagct ggaaaaagag
    72301 gtaatgacgc gtcgccgtga aatcttcact ggcatgggta ttgaattcaa actcaatacc
    72361 gaagtgggcc gcgacgtgca gctggacgat ctgctgagtg attacgatgc cgtcttcctt
    72421 ggcgtcggga cttatcagtc aatgcgcggc gggctggaaa acgaagacgc cgatggcgtg
    72481 tacgcagcgc tgccgttcct tatcgccaac accaaacagt taatgggctt tggtgaaacc
    72541 cgcgacgaac cgttcgtcag catggaaggc aaacgcgtgg tggtccttgg cggtggcgac
    72601 actgcgatgg actgcgtgcg tacgtccgtg cgccagggag cgaagcacgt tacctgtgcc
    72661 tatcgtcgtg atgaagataa catgccgggt tcccgccgcg aagtgaaaaa cgcgcgggaa
    72721 gaaggcgtag agttcaaatt caacgtccag ccactgggga ttgaagtgaa cggtaacggt
    72781 aaagtcagcg gcgtaaaaat ggtacgtacc gaaatgggcg aaccggatgc caaaggccgt
    72841 cgccgcgcgg agatcgttgc aggttccgaa catatcgttc cggcagatgc agtgatcatg
    72901 gcgtttggtt tccgtccaca caacatggaa tggctggcaa aacacagcgt cgagctggat
    72961 tcacaaggcc gcatcatcgc cccggaaggc agcgacaacg ccttccagac cagcaacccg
    73021 aaaatctttg ctggcggcga tatcgtccgt ggttccgatc tggtggtaac cgctattgcc
    73081 gaaggtcgta aggcggcaga cggtattatg aactggctgg aagtttaagc tctgtcccag
    73141 cgccgcctcc tcagaaaaga gtcggcgctg aaattctcct ttctttctgg aaagcgcctc
    73201 gcataatctg aagaaaacca atgtaatacg ctcatctgga ttgttaccgg tagatgcccg
    73261 gcgtatagct gattccatta ttcaacgcag cgccatataa agggacagat aatggaatcg
    73321 ctctcagaga gaacctcaac aggctaccag caaatccacg acggtattat tcatctggtc
    73381 gatagcgccc ggacggaaac ggtacgtagc gttaacgcgc tgatgaccgc gacatactgg
    73441 gaaattggcc gacgaattgt cgaatttgaa caaggtggcg aggccagggc tgcgtatggt
    73501 gcgcagctaa tcaagcgact atcaaaggat ttaagtctaa ggtataagcg tgggttctct
    73561 gcaaaaaact tacgccaaat gaggcttttt tacctctttt ttcaacatgt tgaaattcgc
    73621 cagacagtgt ctggcgaatt aacaccattg ggaattccgc agacaccatc tgcagaattc
    73681 ccatcggcaa agatttggca gacgctgtct gccaaatctt tccccctgcc ctggtccacc
    73741 tacgtccgtt tactttccgt taaaaacgct gacgcccgca gcttttatga aaaagagacg
    73801 ctccgctgtg gctggtctgt tcgccagcta gaacggcaaa ttgcgaccca attttatgag
    73861 cgaacactac tgtcacatga caaatcagcc atgctgcaac aacacgctcc taccgagacg
    73921 catattcttc cgcagcaggc gatacgcgat ccctttgtgc tcgaatttct ggaattgaaa
    73981 gatgaatact cagaatccga ttttgaggag gcgctgatca accacctgat ggatttcatg
    74041 ctggaacttg gggatgattt tgcctttgtt ggtcgacagc gaaggttacg cattgatgac
    74101 aactggtttc gtgtcgatct gctgtttttc caccgccgtt tacgctgcct actaatcgtc
    74161 gatctaaaag tgggcaaatt cagctatagc gatgccggac agatgaatat gtatctcaac
    74221 tacgccaaag agcactggac gctaccggat gaaaatccgc ccatcggtct ggttctctgt
    74281 gcagagaaag gagccggaga agcacattat gctctggcag gtttgcctaa caccgttctg
    74341 gcaagcgaat ataagatgca actacctgat gagaaacgac tcgcagatga actcgttcga
    74401 acacaggcgg tgctagagga aggctataga cgccgttaat ttcagcggtt tcgaattctg
    74461 cagacagtgt ctgcagaatc tttaaaacga actaagtttt aagccattaa atcagcctta
    74521 accttcacca caaccttttt aatctctcca ggctcgccga caacgcatcc tggtttatgc
    74581 ggttcacctg gcataaacac ggcgaacatt cccggtttta agatgatggt ttgctcgttt
    74641 tcaatggtgc tgcaaagctg ataatcatcc tcatggtgga actcttcaca ctggcgcgca
    74701 gtgcctgcca tgccaaacag aatccgttcc tcaccgttta ataacagttg gatatcaatg
    74761 tattgctcgt gcaattccgc ttttttctcg acgggcgatt gagtgttaaa cgtcatgaca
    74821 ttcataaaga tattgtcgcc ctgtaattcg taacgacccg gcgctttttc ttgcggcctg
    74881 gcggctaatg ccagcgttaa cgcgtcctgt aacgcaggat gtaacccagc agacggtaat
    74941 gactgtactt cacccatcat cataattttt ctccctgggc caacagcgca gccccaagta
    75001 aacctgcatc atggcggtag tgcgccgcca gtaaatcaac atgaaatgcc gctggctcct
    75061 gcgccagata cgtttccacc agcgccagat acccttctgc cagaccaacg ctgccaccga
    75121 ccaccacgca ctggcaatca gttgtggctt taatatcagc gatcagcctt gcaagcgtac
    75181 gtgcggagcg atggatcagc cattgcgctt gttcgtcgcc ctgcccggcg cgtgtaaaaa
    75241 tagttctcgc atccgcgccc gccagttcac cctgcgctgc cgccgcaatg ccgcgaccag
    75301 aagcaatcgc ttccacgcaa cctgtgcgtc cacagccgca gactggacca tgcggatcgg
    75361 caagcgtatg cccgatatgc cccgccagac cgccagggcc ggtaagcagt ttaccgccgc
    75421 tcactacacc gccgccgacg ccagtggaaa cggtgataaa caccatctcg gttacatcgc
    75481 cttccagcgc ctgatactct gcccatgctg cggcctgcgc gtcgttaatg gcaatggtcg
    75541 gcaaattggt aagttgttcc agcgttttga ctaacggaaa gtgtagcaat ccaccgagat
    75601 tatgcggatt cagcgccagc aaactgccgt cgcgaataat tccggttgaa gcgatggcaa
    75661 cccgctgcgc atgagcttgc aacggagaga ctaatgcgga taaggcatca cgcaaggctt
    75721 ctggtgtctg gctggctggc gtaggaagtt cacgacgatc gcggatctgc ccgtcagcgc
    75781 caatcagcgc ggcggcaagt ttagtaccgc cgatatcaat cgccagtgtg gtcatagcac
    75841 cgcctttttc atcgctgtgt tgtaccactg acaaatgtgt tcaagacgcg taatggcaga
    75901 accgaccgtc accgcccacg cgccgtggcg catcgcatct gccgcctgag caggcgtgtt
    75961 gtaacgccct tcggcaatca cccgacatcc ggcgtcgctc aacgttttca ccagcgccag
    76021 atccggctct tctggcgttt caggcgtggt atagccagaa agcgtagtgc caataatttc
    76081 ggctcccagc ttttggcatg ccaggccgtc ttccggcgtt gagcagtcgg tcatcgccag
    76141 taaaccgtga tggtgaatac gtgccagcag cgtttcaaca ggcaccggac gcgggcggtc
    76201 ggtgccgtca atggcgataa tgtccgcgcc cgcctgcgcc agcgcatcga catcttcaat
    76261 ataggccgtg atgcgtaccg gagaatcctc cagatcgcgt ttcacaattc caataatcgg
    76321 cacgctcacc accgcacgcg tggcttgcag atttgccaca ccttcaatac gaatggcgac
    76381 cgcgcccgcc tgctctgccg ctaatgccat ggcggcgacg atttcgggtt tatcgagcgg
    76441 gctgtcagga accggctggc aggagacaat caggccaccg ttagcagcga ttttttgatc
    76501 cagttgtgca agtaacgaca tacatcttcc cttagcgaaa ggcccggtac agagaccggg
    76561 caacaggatt aacttttggt tttgactaaa tcgtttttgg cgctgccaaa cggcacggca
    76621 ccgctgaatg gtttaccgtc gatagcgtca tgagtacgca acgcttccgg gcgcaaccaa
    76681 cgctgaacgc gagaaggcat atccagccca atcagcagga tcaccacgaa cgtcagactg
    76741 aacgagagcg atgccagcgc agtacccaga tccagacgtt gagcgatcaa cgcgccgatg
    76801 attggggcca gtgcaccgcc caatgcgcca acgttgtagg taaagcccag gcccgctgca
    76861 cgctggtcgg tatcgaaata accgccaatc agttttggta agatcccggc gatcccttgt
    76921 ccaagcattt gctggaagaa cagtaacaga ccgagcaccc agacgtttgc gccgccaatc
    76981 gcaaataccg gaataatcag cagctgcgag gccagcaggc tacaaacgta cgctttgcgg
    77041 gttcccagcc agtcaccgag gaagccacct acgcagcatc ccaccgccgc gccaaagcca
    77101 ctaaagaaca gcacattggc tacagtatgc gggttataag ccagatcggt tttcagatac
    77161 gttggcagca gcgcctgaat cggccatgag tagaggaaag caaacaacac gaccaccatc
    77221 agcattacgc ccgttggcca gcgtttgcct gtactctgca ccataaagct gataaagatt
    77281 gcggcgcata acagcccaag aacagcgacg atcgcggcat tttgcaggtt accggcgaag
    77341 cagaaccaca gcgcagtagc cgccgccagt gtcattacga tattggcaat gcgatgttca
    77401 ccacggtaga gaatatccac cattgtgcgt actggtgctt tacctgcgtg tttctctttc
    77461 cagtcttccg cttccgggat gtttttacgc agccagagag caaagatgat tggcaaaatg
    77521 ccgataaaga acagcgcacg ccagccccag accggaacca ccaggctata gacctgagcg
    77581 gcaacgacgg cccccacaga gaagcctgaa atcagaaaac cactggcttt gttacgcaga
    77641 tgttttggcc agctttcaat gacataggtg gcgctggaac cgtattcacc cgccatcccc
    77701 atgccgatga ccagacgcgc gataaacatg gtgatgtagc ctggcgcaaa gccgcaggcc
    77761 agcgtcccgg ccgagaagag aacgatgctg gtgaccattg ccagacgacg cccgtagcgg
    77821 tcacccatag cgccgagcat caggccgccg aaccagcgag agataaaggc tgcggagatc
    77881 agacttgccg cctgcaccgt cgtcagcccg aattcaccct gtacttcggt gagtaccagg
    77941 gcgattaaaa cgaaatcaaa accgtcaagc agatatccca accaggcagc ggaaaatgcg
    78001 cgccattgtg cacggttgag atggcgatac cacgggatat tctgggttgt agtactcatt
    78061 gtgagtctcc cgcggtgggc gatgcccaca cgctttggta taaaaattgt agggtacaga
    78121 tgcgtttatt tcccctcacc cggtaggggc gagcgagggg aaacaactca cccgcgctct
    78181 tgcatcaact gctgggccag cgccttcagt tctggcagat atttttcatc taccggtcca
    78241 aacggtttgc ggcacagcgg cacagaaacg acatccatat aatggaggac agttttcagg
    78301 ccgcggaata cgcccgtttt gatcagtaaa tcaatgactt tattgcattc agtttgcagt
    78361 ttctgcgcgg tctggatatc gccttctttc agcgccttaa cgatcccctg atagcgccag
    78421 cccatgatgt tgtaggtact accgatacca ccatcagcgc ccgccagcag accagaggcg
    78481 aagatttcgt cgtaaccgtt atagagcaca agatcaggat gttcacgacg gatctgctcc
    78541 atctgataga gatcgccaga ggtctgtttc agcgcaccta cgccaggcaa tgtaacaagt
    78601 gtgttgatct gatccagggt cagttttacc ccactcaggg ctggaatgtt gtacaccacc
    78661 atcggcaaac catccgccga atcaataatt gcccgatagt gatcgcagtg ttcttcaaag
    78721 ctgaaaggat agtagaacgg cgtgacggcg gagacggcat cgaagccata acgtttagcc
    78781 gatgccgcaa gttgttggct ttcggcggtg ctgacgcaac cgacgtgggc gatgagttta
    78841 atcttacctt tcgcctcttc ggcgacgatt tccagtacct gttcacgctc ggaaaggctt
    78901 tgtacaaagg cctcgccggt cgaaccaccc acgtataaac cgtcgatgcc ctgctgaata
    78961 ttgaactgaa ccaggcgacg cagactcgct ttatccagtg cttgttgttg gtcaaaagga
    79021 gtcaggagtg cagccattac gccacgtaaa ttcgttgcca taaatacctc tgaagtgatg
    79081 cttgtctgat aaacgatata cctttatacc tgttatacca gatcaattaa gcaacacccc
    79141 atacagaaag cttataatgc gatctgcttc actaaagtgg cattatttct ttttgttggt
    79201 ggtctgaccg aaagcgtgcc aggtagcaga gacgctgttg agatgcgatt gcaacgcacg
    79261 atcggcttcg tcaggatcat gacggcggat cgcatcaacg atcgcaatat gctgttgata
    79321 actaacgttg ttatgttcgt gcagtgcctg atcggtaacc gttgggcgtg cggcaataag
    79381 ccagtcgagc agggcaacgt ggatcgccat gaagattggg ttaccgggga tctccgccag
    79441 cacgcggtgg aaatcaacgt ctgaacgaat gaatgccgcg ttgttatcca gcgactgact
    79501 gttgatttcc agtgcttttg ccagcaaatc gatttgctca tcggtggcat gttcagccgc
    79561 atagcgcacc aggctggatt caaagaacag acgtaattgt tcgaaatggg caatcccacc
    79621 aggatgagaa aggaaatctt tcgccatgcc ggaaagctcg ccgatgatgg tgtccgcaga
    79681 aggacgtgag acgcgggcac gttcgccgtt gttgatttgc accagacctt tgcgttttaa
    79741 cgctgccagc gcttcgcgca cagaaggacg cccgacgtta aagaacgcca tcagttcgcg
    79801 ttcagacggt aattgttcac cttcgccaaa ttcacgacgg cggatcatct gttccagctc
    79861 ttcttccacc atttcggaga gttttttacg cgccagcggg cggctacgca agttgcgacc
    79921 aattgcaggt gaagaatctt cggtttgcga atcaaatgcg ttcataaggc ccattctgta
    79981 aggtcagtgt gattaacatc atcagtgaca tcctatcaca ggattgaaag taggggaaaa
    80041 tggcaggttt ttctctttgt gcctcatcat taccataatt aacggaataa ttaactattg
    80101 cgaaaaatta atgtaacgca gataaaaaca tcccgtttga attatttata agactattca
    80161 cgagcattat gaatattatg aatgtgttct tacaaaataa tcataagcgc atatttttta
    80221 atgaaaaatc acctcaccta caattaaaaa cacgacatcc gcaccataaa tagacttgca
    80281 aaaaatataa catcattgtt ttcaatctgc cgtttatggg attgaccgtt ttcttttgac
    80341 acggagttca acaatgttcg gcataattat atctgtcatc gtattaatta cgatgggcta
    80401 tttgatcctg aaaaactaca aacctcaggt ggtgctggct gccgcaggta tcttcctgat
    80461 gatgtgcggt gtctggttag ggttcggtgg tgtactcgat cccgccaaaa gcagcggcta
    80521 cttgatcgtc gatatttata atgaaatcct gcgcatgctg tccaaccgca ttgccggatt
    80581 ggggctgtcg attatggcgg tgggcggtta tgcccgctac atggagcgca caggagccag
    80641 tcgcgcgatg gtgagcttgc taagccgccc gttaaaactc attcgctcgc cgtatattat
    80701 tctgtcggca acttacgtca tcggccaaat catggcgcag tttattacca gcgcctccgg
    80761 cctgggtatg ttgctgatgg tcaccttatt tccgacgctg gtgagtctgg gagtaagtcg
    80821 cctctctgcg gtggcggtta tcgcaaccac gatgtccatt gagtggggga ttctggaaac
    80881 gaactccatt tttgcagccc aggtcgcggg aatgaaaatt gccacttact tcttccacta
    80941 ccagcttccg gtcgcctctt gcgtcattat ctcggtggcg atctcccact ttttcgtgca
    81001 acgcgctttt gacaaaaaag ataaaaatat caatcacgaa caggcagagc taaaagctct
    81061 cgataatgtc ccgccgctct attacgccat tttacctgtg atgccgttaa tcttgatgct
    81121 cggctcgctg ttcctcgccc acatcgggct gatgcagtca gaactgcatc tggtggtggt
    81181 gatgttactg agtttgacgg tgacgatgtt tgttgagttc ttccgcaagc ataacttgcg
    81241 cgaaacaatg gacgatgtgc aggcgttttt tgacggcatg ggtacgcagt ttgccaacgt
    81301 ggtaacgctg gtggtcgcgg gtgaaatatt tgcgaaaggc ttaacgacga ttggcactgt
    81361 tgatgcggtt atcaggggtg ctgagcattc tggtctgggc ggtattggcg tgatgattat
    81421 tatggcgcta gtcattgcca tttgtgccat tgtgatgggc tctggcaatg cgccgtttat
    81481 gtcatttgcc agtcttattc cgaatatcgc agccggacta catgtaccag cggttgtaat
    81541 gattatgccg atgcattttg ccacgacgct agcgcgcgcg gtttcgccga ttactgcggt
    81601 ggtggtcgtt acgtcaggaa ttgcaggcgt ttcgcctttt gcggtggtga agcgaacagc
    81661 gatccccatg gcagtcggtt tcgtggtgaa tatgattgcc acaatcacgc tattttatta
    81721 agccattaaa agacaaaaca ggccaccagg gcctgttttt gtattacttc acaacgcgta
    81781 atgccggtcg accaccgcgt ggtggctgcg gaggttcatc gtcaggatga gtgtcatcat
    81841 cgtgatctgg cttgtcgcca tcaataaccg acataacggt ttcgttgtct gccgatgcct
    81901 cttcatcatt catgatgctg gtatcttcat cgtaggcagc ttcaggctca aacatcgtgc
    81961 ctgcgccatt ttcacgggcg tagatagcca gcacggcagc cagcggcaca gaaacctgac
    82021 gcggaatgcc gccaaagcgc gcgttaaagc gtacctcatc attcgccagt tccagattgc
    82081 cgacagcacg cggcgcaatg ttgagtacga tttgcccgtc acgcgcatat tccataggaa
    82141 cctgcacgcc agggagcgtc acatccacca ccaagtgcgg cgtgagctgg ttatccagca
    82201 accactcata gaatgcacgc agcagatagg gacgacgtgg tgttagctgt gacaaatcca
    82261 tacagattaa ctccggccca gacgcatttc acgttctgct tcagttaaag aagcaaggaa
    82321 agagtcacgc tcaaagacgc gggtcatata gcctttcagc tctttcgcac ccgggccgct
    82381 gaactcgatg cccagttgcg gcagacgcca cagcagcgga gcaagatagc aatcgaccag
    82441 gctgaactca tcgctcagga agtacggctt ctgaccgaag accggcgcaa tcgccagcag
    82501 ttcttcgcgc agttgcttac gtgcggcatc tgcttcagaa gctgaaccgt tgatgatggt
    82561 gttcatcagc gtgtaccagt ctttttcgat gcgatgcatg tacagacggc tttcaccgcg
    82621 agctaccggg taaacaggca tcagtggcgg atgcgggaaa cgctcatcca gatattccat
    82681 aatgatgcga gattcccaca gggtcagctc acgatccacc agggtcggaa cgctctgatt
    82741 cgggttgagg tcaatcagat cctgaggcgg attgtccttt tccacgtgtt cgatctcgaa
    82801 acttacacct ttctcagcca gcacaatgcg gacctgatgg ctatagatgt cagtaggacc
    82861 ggaaaacagc gtcattaccg aacgtttgtt ggcagcgaca gccatgaaaa cctccaggta
    82921 tagtcagaat ttttactgct accagccacc aggtggccag tcagaagttg tgttacccag
    82981 taaggaacga ctctctttgt tcgaaaatca aacaaaaaat gagcaatacc cgacatttgg
    83041 gcagaaaatt ggatgatagt ttaccagatt ttgcgacctt tgtggtgagt cgatgccgga
    83101 aatggggaaa aagagatgcg ctttagtctg aaatagttga cttagtccct tattggcgat
    83161 gtggtttttg ttttgcctgt ctgtcagacg gtagcaaaaa gcaactttcc aatttttacg
    83221 ctgattcaga atttaaccat aaaaaaaccc gccgaagcgg gttttttcgc aaattgtttt
    83281 ctgccggagc agaagccaat taacgtttgg agaactgcgg acgacgacgt gctttacgca
    83341 gaccgacttt cttacgttca acctgacgag cgtcacgagt aacgaagcca gctttacgca
    83401 gttcagaacg cagggactcg tcgtattcca tcagagcgcg ggtgataccg tgacggatcg
    83461 caccagcctg accagagata ccaccacctt taacggtgat gtacaggtcc agtttctcaa
    83521 ccatgtcgac cagttccagc ggctgacgaa ctaccatgcg agcagtttca cgaccgaagt
    83581 actgttccag agaacgttgg ttgattacga ttttaccgtt gcccggtttg atgaaaacgc
    83641 gagctgcgga acttttgcgg cgaccagtgc cgtagtattg attttcagcc attgcctata
    83701 atcccgatta gatgtcaaga acttgcggtt gctgtgccgc gtggttgtgc tcgttacccg
    83761 cgtaaacttt cagtttacgg aacatagcac gacccagcgg gccttttggc aacatgcctt
    83821 taaccgcgat ttcaatcaca cgctcaggac ggcgagcaat catctcttca aaggtagctt
    83881 gtttgatacc accgatgtgg ccggtgtggt gatagtacac tttgtcagta cgcttgttgc
    83941 cggttacagc aactttgtca gcgttcagaa cgatgatgta atcaccggta tctacgtgcg
    84001 gagtgtattc cgctttgtgc ttaccgcgca ggcgacgagc cagttcagta gccagacggc
    84061 ccagagtttt accggtcgcg tcaacaacat accagtcgcg ttttacggtt tctggtttag
    84121 ctgtaaaagt tttcattaaa agcttaccca ataaatagtt acacgttggt gaacacccaa
    84181 acgtcttcaa ttgttgaggt tcacacgaca aagtccggca aacctacccc ttcgaatagc
    84241 ctatgccagc acacaaaaag ttttgggaaa aaaactttct tgtaacgtgg ggtcgcagga
    84301 ttatagagaa gtcggggtca aagatcgacc cctttttgtg atttgtgaca ggttttaacc
    84361 cgccaaatgc tcgcgcttca gatactcttc gctttgcatc tcttgcagac gtgacaggca
    84421 acgctggaac tcaaacttca gccgatcgcc ctgataaatt tcatacagcg gcacttctgc
    84481 actcaccact aatttgacat ggcgctcgta aaactcatcc accagcgcaa taaagcgccg
    84541 cgcttcgctc tccatcaacc gcgtcataac tggtacatca aacaacatga ccgtatgaaa
    84601 gagacgtgag agcgcaatat agtcatgctg actgcgggcg tcgacgcaca gcgtagtaaa
    84661 agagaccgcc agcgtctggt tctcgacgcc cattgtcgcc aatggccgat ggttgatttc
    84721 taacgtcggt gaattttctc gtttcgcccc cgccagcgcc aaccatagtt tatccatctg
    84781 cgcccgggtt tcatcgttga gtggcgaaag ccacagatgc gcctgagtga gtgtacgcag
    84841 tcgataatca acaccagcgt ccacgttcat tacatcacaa tgctgtttaa tggcatcgat
    84901 tgcaggcaga aaacgcgcac gttgcaggcc atttcgataa agttcatccg gcggaatatt
    84961 tgacgtcgct accagggtaa tgccgcgggc gaacagggct ttcatcagac cgccaagtag
    85021 catggcgtcg gtaatatcag aaacaaaaaa ttcgtcaaaa cagagcacgt cagtttcggc
    85081 tttaaagcga tcggcaataa tttccagcgg atcggtctgc ccctgtaagg cagttagctc
    85141 ttcgtgcacc cgcagcataa aacggtgaaa gtgcaggcgc tgtttccgct ctcccggcag
    85201 gctttgatag aaaaggtcca tcagccaggt tttcccgcgt cctacaccgc cccacatata
    85261 taagccacgc actggcgtat gctttgtgtc ttcgcgttta ccccacagct taccgacccg
    85321 cgccattagc ccactcgtcc tgggggctgg tggcctgcta ttgatgagtt cttgataaat
    85381 aatttccagg cggctgacgg cctctttttg aacgtcgtcg ggttgatggc tgccttcatt
    85441 gagcgccttc aggtattgcg atgttggggt aacgctttgc atgatcttat tgttattcct
    85501 tgaataatcg gtgcgccgtt gttcacggtt gacgaaaaaa aggccgttct acactacgcg
    85561 atatgcagtc gggattccac ttctgtggaa ttaacggtta tagtggcata atcagccgca
    85621 ggcatggagc ctgaagccaa caccctacgg aaacaaaaga caacgggaga tgttcatgac
    85681 ctgggaatat gcgctaattg ggttagtcgt cggcatcatt attggtgctg tggccatgcg
    85741 ttttggtaat cgtaaactac gccagcaaca ggcgttgcag tacgaactgg aaaagaataa
    85801 agctgaactg gacgagtatc gcgaagagct ggttagccac tttgcccgca gcgcggaatt
    85861 actggatacc atggcgcacg actatcgcca gctgtatcag cacatggcga aaagctccag
    85921 cagcctgctg ccggaactgt ctgctgaagc aaacccgttc cgtaatcgtc tggcagagtc
    85981 tgaagccagc aacgatcagg caccggtgca gatgcctcgc gactattctg aaggtgcatc
    86041 cggcctgctg cgtactggcg cgaagcgcga ctaatttatt tttcgggcgc agccattgcg
    86101 ccctcctctt ctctccctcc ccgactatca tttaatctgg tgtctcattg ttagccgtct
    86161 gaaaattcaa taacatcaaa ctgttttgaa tctcttttct tatcattcag gtacgagagc
    86221 aggaataatg aaaaaacaaa cccagctgtt gagtgcatta gcgttaagtg tcgggttaac
    86281 tctctcggcg tcatttcagg ccgtcgcgtc gattccaggc caggttgccg atcaggcccc
    86341 tctccccagt ctggctccaa tgctggaaaa agtgcttccg gcagtggtga gcgtacgggt
    86401 ggaaggaacg gccagtcagg gacagaaaat cccggaagaa ttcaaaaagt tttttggtga
    86461 tgatttaccg gatcaacctg cacaaccctt cgaaggttta ggttccggtg tcatcatcaa
    86521 cgccagtaaa ggctatgtgc tgaccaacaa ccatgtgatt aatcaggcac agaaaatcag
    86581 tattcagctc aatgatgggc gcgagtttga tgcaaaactg attggtagcg atgaccagag
    86641 cgatatcgcc ctgttacaaa ttcaaaaccc gagcaaatta acgcaaatcg ctattgccga
    86701 ctccgataaa ttgcgcgtcg gtgattttgc cgtagcggtc ggtaacccat ttggccttgg
    86761 gcaaaccgcc acctctggca ttgtttccgc attaggccgc agcgggttga atcttgaagg
    86821 tctggaaaac tttatccaga cagatgcttc cattaaccgc ggtaactccg gcggtgcact
    86881 attaaacctt aacggtgagt taattggcat caacactgca atccttgcgc ctggcggcgg
    86941 gagcgtcggg attggatttg ccatccccag taatatggcg cgaacactgg cgcagcagct
    87001 tatcgacttt ggtgaaatca aacgcggttt gttaggcatc aaaggcaccg agatgagtgc
    87061 cgatatcgcc aaagccttca accttgacgt gcagcgtggc gcgtttgtca gcgaagtgtt
    87121 gccaggttct ggctcggcaa aagcgggcgt caaagcgggc gatattatta ccagcctcaa
    87181 cggcaaaccg ctgaatagct ttgctgagtt gcgctctcgt atcgcgacca ccgagccggg
    87241 cacgaaagtg aagcttggcc tgctgcgtaa cggcaaacca ctggaagtag aagtgacgct
    87301 cgataccagc acctcttcgt cggccagcgc tgaaatgatc acgccagcgc tggaaggtgc
    87361 aacgttgagc gatggtcagc taaaagatgg cggcaaaggt attaaaatcg atgaagttgt
    87421 caaaggaagc ccagctgctc aggctggctt gcaaaaagac gatgtgatca ttggcgtcaa
    87481 ccgcgatcgg gtgaactcga ttgctgaaat gcgtaaagtg ctggcggcaa aaccggccat
    87541 catcgccctg caaattgtac gcggcaatga aagcatctat ctgctgatgc gttaatgtcg
    87601 taaaccgggc atcaggctta cgtgtgatgt ccggttaact cgtggtatgc tgctgccgtt
    87661 ccctttttta atgacgcctc catcatgttt gtgaagctct tacgttccgt tgcgattgga
    87721 ttaattgtcg gcgctattct gctggttgcc atgccttcgc tgcgcagcct taacccgctt
    87781 tccactccgc aatttgacag taccgatgag acgcctgcca gctataatct ggcggttcgc
    87841 cgcgccgcgc cagcggtggt taacgtttac aaccgtggtt tgaacaccaa ctctcacaac
    87901 cagcttgaga tccgcacctt gggatccggt gtaatcatgg atcaacgcgg ttatatcatc
    87961 accaataaac acgtcatcaa cgacgccgat cagatcatcg tcgccttaca ggatggtcgt
    88021 gtatttgaag cattgctggt gggatctgac tctctaaccg atctggcggt acttaaaatt
    88081 aatgccactg gcggtttacc taccattcca attaatgcac gtcgcgtacc gcacattggc
    88141 gacgtagtac tggcgatcgg taacccgtac aacctcgggc agaccattac ccaggggatt
    88201 attagtgcca cgggtcgaat cggtctgaac ccgaccgggc ggcaaaactt cctacaaacc
    88261 gatgcttcca ttaaccacgg taactctggc ggcgcgctgg tgaactcgct gggagaactg
    88321 atgggcatta acacgctgtc gtttgataag agtaacgatg gcgaaacgcc ggaaggtatc
    88381 ggctttgcga ttcctttcca gttagcaacc aaaattatgg ataagctgat ccgcgatggt
    88441 cgcgtgatcc gcggctacat tggtatcggc ggacgcgaga tcgcaccact gcacgcgcag
    88501 agcggtggta tagatcaact gcaagggatc gtggttaatg aagtgtcacc agacggccca
    88561 gcggcgaatg cgggtattca ggtcaacgat ctgattattt cggtggataa caaaccggcc
    88621 atctctgctc tggagacgat ggatcaggtg gcggaaattc gccctggttc ggtgatcccg
    88681 gttgtagtga tgcgtgatga taagcagtta acgctgcagg tcaccattca ggaatatccg
    88741 gcaaccaatt aagtcgagtg ctcaaaacaa aaaccggagt ctgtgctccg gttttttatt
    88801 attcgctaat caattactta ttaacgaact cttcgcccag ggcgatatct ttcttgagcg
    88861 tatccagcat accttccagc gcgttctgtt caaatgcgct cagggtaccg atagatttac
    88921 gctcttccac gccgttttta cccagcagca gcggttgaga gaagaaacgg gcgtactgac
    88981 cgtcgccttc aacgtaggca cattcgacaa cgccttgttc gccctgcagt gcacgaacca
    89041 gagacagacc aaaacgtgca gctgcctggc ccatagacag ggttgcagac ccgccaccgg
    89101 ctttcgcttc aaccacctca gtacccgcgt tctggatacg tttggtcaga tcagccactt
    89161 cctgctcggt aaaactaacg ccaggaacct gtgacagcag cggcagaatg gtaacaccag
    89221 agtgaccgcc aataaccggc acttcaactt cgcctggctg tttgcctttc agttccgcaa
    89281 caaaggtgtt ggaacgaatg atatccagcg tggtaacgcc gaacagtttg tttttgtcat
    89341 aaacaccggc ttttttcagc acttcagcag caatcgcaac tgtggtgtta accgggttag
    89401 tgataatacc aatgcacgct ttcgggcagg ttttcgcaac ttgctgtacc aggtttttca
    89461 cgatgccggc gttaacgtta aacaggtcgg aacgatccat acccggttta cgcgctacac
    89521 ctgcagagat aagaacgaca tctgcgcctt ccagcgccgg agtcgcatct tcaccagaaa
    89581 aacctttgat tttcacagca gtagggatat ggctcagatc gacagccaca ccgggagtca
    89641 ctggagcgat atcatacaga gagagttctg aacctgaagg cagttgggtt tttaacagta
    89701 gtgcaagcgc ctggccaata ccgccagcag cgccgaggac tgcgactttc atcctaaact
    89761 ccttattata ttgataaact aagatatgtt gctccgctgc cgcgacctta atccacaaaa
    89821 ttgccgttta caatgaccac atctcaagaa tgtgtagtca cgcaagttta gcgtttatgc
    89881 atttaattgc cgtaatcagg aacctaactt acgtaattaa cagtcgctta tgcattagcg
    89941 caacattcca acaggtggtg acaatatacc ctaccgttca gccaaaacaa catcaatttg
    90001 ataacaatta atttactttt aagcagaatt tgcatgccgt gacgcaggca tgtttctcaa
    90061 taacgaaatt tgataaaatc ccgctctttc ataacattat ttcagccttc ttcagggcta
    90121 actgtttgca taaaaattca tctgtatgca caataatgtt gtatcaacca ccatatcggg
    90181 tgacttatgc gaagctcggc taagcaagaa gaactagtta aagcatttaa agcattactt
    90241 aaagaagaga aatttagctc ccagggcgaa atcgtcgccg cgttgcagga gcaaggcttt
    90301 gacaatatta atcagtctaa agtctcgcgg atgttgacca agtttggtgc tgtacgtaca
    90361 cgcaatgcca aaatggaaat ggtttactgc ctgccagctg aactgggtgt accaactacc
    90421 tccagtccat tgaagaatct ggtgctggat atcgactaca acgatgcagt tgtcgtgatt
    90481 cataccagcc ctggcgcggc gcagttaatt gctcgcctgc tggactcact gggcaaagca
    90541 gaaggtattc tgggcaccat cgctggcgat gacaccatct ttaccacccc tgctaacggt
    90601 ttcacagtca aagacctgta cgaagcgatt ttagagctgt tcgaccagga gctttaatct
    90661 ctgccccgtc gtttctgacg gcggggaaaa tgttgcttat ccctctcaat cccctgcttt
    90721 cccctgcgat tcatttaacg aatagtgcgt tttaccgcga catatcattc acgcaatgaa
    90781 tacatgcggt aaaaaaagca cattatgcaa aattcattat ctgattgaaa agactggtat
    90841 ttataataaa taaccgtgtt tttaatactt ttttgttatt aaaattcaca tttttaacac
    90901 ttagtatcaa ctgaaacagt tagcgtggta ttaattagtt caataattag tgtatacttg
    90961 attttgtgat atgggtcact aaacaaaggc ccagctaaaa gattatgtcg aggtaaaaat
    91021 catgaaaatc aaaaccactg tagctgcatt aagcgtactt tctgttctct ctttcggtgc
    91081 attcgctgcc gactccattg atgctgcaca agcacaaaat cgtgaagcaa tcgggaccgt
    91141 atccgtaagt ggtgtggcgt cttcgccaat ggatatgcgt gaaatgctga acaaaaaagc
    91201 ggaagagaaa ggcgcaacgg cctaccagat tactgaagct cgtagcggtg acacctggca
    91261 cgctacggct gaactgtaca aataaaccct catcgtcttg tccgacgata ttgcccccgg
    91321 ttcgggggct ttttttgcgc taatgacgaa cattaaaacg caaatgccct tccagctctt
    91381 cctctgcctc atcaaacagc aatattaacg cgccaaaacg gcgacgcgtt ttctctccca
    91441 gatgaacaaa ttcaatctca agtggtagcg gcaggacatc gttcattaac acatcccata
    91501 gtgagtcgag atcgcgtacc ttatctttcg ccagaccaaa ggtttggcta aagtcacgat
    91561 aaaaatcctc ctgactctca atctcatcaa aatcaaaggt ataaatattc atctgttgcc
    91621 accgtcacgt ttcgcggcga gttctgccgt gcatcgctaa gtatagccat gaaaaaaccg
    91681 acgcttttgg cgtcggtttt gacttaacta tcggtcaacg catgttgata cttatggagc
    91741 atccccgcca gccgatgaac cggttccgtc acctgcggtg gcgcttgcca gatgcgtagc
    91801 ttttcctggt agatttccag ttcttccagc aactggccaa agtaccgacg acgtttatca
    91861 tcgctacggg cagatatcac atggtctgct gtgcggcgca tttgtcggtg aaacgccgat
    91921 aaatcctcgt taaccgggat cggcgcatca cgcaggcgct ggtgcgcgat aatcatcgtc
    91981 agcgccaggc gaaatttcgg caaatcccct gggaacttat tcatcagcaa aaacagctgc
    92041 tgataaagtg ccgggaggtg gttctcttta cgacgtgcca cattggtagt catcgcggaa
    92101 acagcggcag aaacaaactg attaagcagt acacgtccag tcctgtcgcg cgatttatcc
    92161 cgcaccagca aaataacggt gaacgcgagc acacagccga cgatttgccc taatgcgctg
    92221 tcgagaaact gactgaaatg gaaagtcatc gggttatcca gcacgataat atttatggtg
    92281 ctggccagcg cccccatcga gcccagtcgc cgtttctgta cttctattcc gaggaagaat
    92341 cccagcactg ccaggctaat acacagcagc aacatgctct gttgggtatt agggataatc
    92401 accaaaaagt agagcagccc taacggcagc gcggccagcg tcccgtagat aaagtcgatc
    92461 gccaccatgc gtggattcgg caaacgcatt gccagtgacg tcacgaccgc aatcatcacc
    92521 attgcaccac tgccggaagt ccagcccgtc cacagccaga aaagcgttcc cagaatgcag
    92581 gaaagtgtgg ttcgccagaa gttaaccatc gcatgatgac gttcggctga ctctactttg
    92641 acttccggtt cgccttgcag gatctcttct tcggtggcgt tgatttttgt gttactgata
    92701 acgccgcgct tgagaagctg ataacgcgtt gccgccgcga cccagctata aatggtgaca
    92761 ggcgtttccc gttccccggt ccaggcgata actctccgca ggcgtttgag ctgcttgtgg
    92821 acgtcctgcg cggtttctac cggcgtgtca aaaaattcgc ggaaagtatc agtgatcaat
    92881 tccgggcgcg tattctgaat aagataagtt tcgcaggatt gggtaatcag cgtcagcgat
    92941 agcgtattga tcgcttttaa acgtcgattg gcccgcgccc agcgggaaga ttccatattc
    93001 aggttgctgc gcatgccttg tagcgccgtg gtgcgtcgca ccaggtcgcc ccaggcttta
    93061 tcgacaactt caccatcgcc atgcttgata cagagttgca ttaattgata ttgcgcgacc
    93121 agcaaacttt ccagctctcg atccacttct tgtttgatcg atcgcggaga aaagagcaaa
    93181 tccgccataa tcgcacacac aataccgata acgatctcgc tacaacgttc gacggcaaac
    93241 tgcggcgtaa gcaatggttc cggctgaatg gtgatcacaa tgatcagcgc ggtataaccg
    93301 gccagccccc acgcgtacga gttttctatt cgtaccagcg aggatatcca ggtacaaaaa
    93361 ccggcccaga tacagcacac cagaatcatc aataatggtg cgcggatcat cgcaatgatg
    93421 atcaccagtc cggcaataca gccaataaat gtgccgatga tgcgcaaaaa gccacgatag
    93481 cgaatagcgc cagaatacgg ttcacctccc gcagcaaagg ccggaccggc ggcaacaatc
    93541 gccgctgtca gtaccgccca gcgtggcgtt tccagctgga agtgaaagcc aacaaacagc
    93601 gccagtacaa tggcggtcgc cagttttacc gcaaagcgaa tatgttggtt agcaatggag
    93661 aaaataccca tcgtgattaa ccaaactcac gcaggcgatg ggccatttta cggaagaacg
    93721 aatcctggct ttcgtcgcga tcttgtttgc cagtgaccac cactgtagca gtggtgcccg
    93781 caggccagat gttctcttgc tggttgtcga gacgaatacg aaccggaaca cgttgcgcca
    93841 aacgcaccca ttcaaggtta gagtcgatgg tcgccatccc tttgtcgtca cgcgtgctgc
    93901 tggcgttggt gaccccagcg gcaacactat caacagtccc tttcagcact ttgttactgc
    93961 caagcggcgt gatctctgca cgataccccg gacgcacccc ttccagctta gtttcttcca
    94021 tataggccag tacatagaag gagttctgtt tcaccagcgc aaccgccgtt gatcctcgag
    94081 taataaactc accggtatag acgttgaggt tggtcaccca gccatctgct ggcgcgcgga
    94141 tcaccgtgcg ttcaagatcc agttttgcca gatcgcgggt cgcctgcgct ttcgctaact
    94201 gatgcagaac cgtttgtagt acgttgttag cctggtcgat ctcttcgcga gacatcgcct
    94261 gcacaccgag acggttacga cgtccggcct cctggcgttt ctcctgtgcc agtacctgat
    94321 aataagcaac atcggcttgc gcttcctcaa gcgccttttg atagcgcggc tggtcgatgg
    94381 tgaacagtat ctgtcctttt ttcaccagct ggttatcatg aacattcacc tgggtaatga
    94441 gtccagaaac gtccggcgcg atcgcaacga cgtcagcgct aaagcgcgcg tcacgcgtcc
    94501 agggggattc ggtgtaatag acccaggcat taaaaattgc gatgaaggcc agaatgacta
    94561 atacgaccgt gatggccgta cgggagaatt ttcttattag tgttttcact tcaacctcaa
    94621 acgaacagtc gcgatatcaa ataaaacaag cagcaataga gcgcggtgtt gaacaacgcc
    94681 ggatgccaga caaagtcgta gatacctgtt ggcacaagta cccggcgcac cagccagaaa
    94741 atcgccagtg ataaaagcaa ttcaaaaaat atcggtggga aggacagccc aaacaccacg
    94801 ataacgggaa acagactcat gttgaccttg gttgtataga gagagcaggc gttattattt
    94861 tcagcatctg tcgccgcaga gaagggcatg gaaagccggg cgagagcaac attgctgtag
    94921 attgatattt aatatattag cgtaactgtt atgctgttat ctatattatg tgatctaaat
    94981 cacttttaag tcagagtgaa taatggaacg actaaaacgc atgtcggtgt ttgccaaagt
    95041 agttgaattt ggctctttta ccgccgccgc cagacagcta cagatgagcg tttcgtccat
    95101 cagtcagacg gtgtcaaaac tggaagatga gttgcaggta aagctgttaa accgtagcac
    95161 acgcagcatt ggcctgaccg aagccggtag aatttactac cagggctgcc gtcgtatgct
    95221 tcatgaagtg caggatgttc atgagcaact gtatgccttc aataacaccc ccatcgggac
    95281 gctacgcatt ggctgttctt caactatggc acaaaatgtt ctcgccgggc tgacagccaa
    95341 aatgctgaaa gaatacccag gtttgagcgt caatctggtt accggaattc cagcccccga
    95401 cctgattgcc gacggtctgg atgtggtgat ccgcgtcggc gcgttgcagg attccagcct
    95461 gttttcccgc cgtcttggcg cgatgccaat ggtggtgtgc gccgcgaaaa gctatctcac
    95521 acaatacggc ataccggaaa aacccgccga tttaagtagc cattcatggc ttgaatacag
    95581 cgtgcggccc gacaatgaat ttgaactgat tgcaccggaa gggatctcga ctcgcctgat
    95641 cccgcaaggg agatttgtga ctaatgatcc gatgacgctg gtgcgctggc taacggcggg
    95701 tgccgggatc gcctacgtgc cgctgatgtg ggtgatcaac gagatcaatc gcggtgagct
    95761 ggagatcctg ctgccgcgtt atcagtcaga tccacgcccg gtttatgcgt tatataccga
    95821 aaaagataag ctgccgctga aggtacaggt cgtgatcaac tcgctgacgg attattttgt
    95881 tgaggtcggt aaattgtttc aggagatgca cgggcgcggg aaagagaagt aattcatatt
    95941 gtactgttac gttctacaaa cctgtgccaa cgggttcccc tcaccctaac cccagaggag
    96001 cgaggggacc gttcgtgcac gtagaaagat taattatcct tctgaaaata atgaaattat
    96061 tacgcagtac cgccaacagt caggttatca actttcagcg ttggctggcc cacgccaacc
    96121 ggcaaacttt gcccttcttt accgcagaca cccacgccgt tatccagttt caggtcgttg
    96181 ccaaccatcg aaatctgctg catggtttcg ataccggaac caatcaacgt cgcgcctttc
    96241 accggcttcg ttactttacc gttttcaatc agatacgctt ctgaagtgga gaaaacgaat
    96301 ttgccggatg taatatccac ctgaccgcca ccaaagttcg gtgcatagat accgtactca
    96361 acggattcaa taatttcctg cggggtcgat ttacccggca gcatataggt gttggtcata
    96421 cgcggcatgg gcagatgggc gtaggattca cggcgaccgt tgccagtcgg cgtcatcccc
    96481 atcaaacgcg cgttgagttt atcctgcatg tagcctttca gaatgccgtt ctcaatcagc
    96541 acgttgtact ggcctggcgt accttcgtca tcaatcgcca ccgaaccacg gcgatcgacc
    96601 atcgtgccgt catcaaccac ggtacacagt tctgaagcca ccagctcccc gacctgccca
    96661 ctaaatactg aagtgccgcg gcggttgaag tcgccttcca gaccgtgacc taccgcttca
    96721 tgcaacagca cgcccggcca acctgcgcca agtactaccg gcatggtgcc cgctggtgca
    96781 gcaacggcag aaagattgac cagcgccata cgcactgctt cttttgccca tgcatccgca
    96841 cggacttcgc cgtcaagatc ggcaaggaag aactcataac caaaacgacc gccgccgcca
    96901 ctggcaccgc gttcgcgttt gccatcttct tcgaccagaa cgctcacgga aagacgcacc
    96961 agcggacgaa catccgccgc cagcgtgccg tcggtggccg caaccagaat taattcataa
    97021 acgccgctga ggctggcagt cacttcttgt acgcgcttgt ccgcttcgcg ggcaacctta
    97081 tcgacgcgac gcaggatatc cagcttctct tcacggctca tgctttgcag cggatctacc
    97141 gaggtataca acgggctatg ctctaccgcg cccagcgtct gtactttgcc atcaccacta
    97201 tcacggacga tggtgcgcgc cgcttgcgca ctctgttcca gcgccagcag gctgatttgg
    97261 tcagcgtaag caaatccggt tttttcacca ctgattgcac gcacaccaac gccctgatcg
    97321 atgttgtaag aaccatcttt aataatgcgg tcttctaaaa cccaggattc gtgatagctc
    97381 gactgaaaat agagatcgcc ataatcaagg cgacgttcgg ccagttgacc gaggatcgcg
    97441 aacaagtcct gatgtttcag gccgttcgcc gctagcaatt gttcacttac caggttcaga
    97501 ctcatcgttt ttgctactcg ttagttactg cagtagagga ttttttacgg ctgccggatg
    97561 cggcgtgaac gccctatccg gcctacagtt atgttccggc tcgttggcct ttggcaacga
    97621 ttatcatatg agattggggc aattacgcgc cctcgtcaaa tcattgcgct ttttctttac
    97681 gcggttggcg caacacttcg ttgatttgcg gatcgtccag cggacccgaa atgtgatagc
    97741 gcaaaatgga gactttgctc cacagcggcc ccagcacttt actggctgca aatactgccg
    97801 cgccaacaat ggggttaacc gcaaaagccg cagccacgcc caccgtcgca gaaatctctg
    97861 gtgcgacaac cgcttccata ttcaggtcgc gacgtaccag atttaccgac cctttcatgg
    97921 cgatatccgc ctccaggcca tccaccagcg tgtcgtcggt gtgcataacc ccgtctttaa
    97981 tccacgcggt gctgcgaatg gagtcaaaat agaacccttc gccaaaagtg tctctgaaat
    98041 caaaacgcag cttacgcatc agggcatcaa cgctcaataa gcgcagcaat tgcccggcat
    98101 gtccggtatt gatttcggta atttcgcctt tacccagttg agtatgaatg atgccattca
    98161 acgtcgcctc atctggttgc cagggtgctt tgcgccagtg taaatcgtaa tccacattaa
    98221 atgacgactg gcgtatgggc gtcgtgacac caaaaaattc tgcggcggca tcaattttct
    98281 gcccgcgcag ttttcctttc agcgaggtac gttcattctc cggattatta acccattcac
    98341 catcggcagt aagccgcgag aaaccagtat caatcagtcc attggtcagc gttaacgtat
    98401 cgccagaaat ggtgatatca ctgtcaatgc gaccgaattt ttgcccccag aaccagcact
    98461 ctgtgcatcg tatttgtgcg tccggccagc cacggaagtt aatgcgctcc gttgtcggga
    98521 aaggtgatga cggcgttgaa tcaccacgag ttttcgccac gctcgggttg taataaagat
    98581 atttgatatt cgccagccac ggcgcgttat tacgcatcgc tagcgtggcg ttgatttcac
    98641 gcccttgcgc ctcaaccagg gtgccatttg ccgtcggttg cgaaacaata ctcaggttat
    98701 tccattgctg atttcccagt gacaacatag gcgtacgtaa cgttatgtgt tgtgggaaac
    98761 tcgctgcacc accgacactc tccgcagcgc ctttctggaa cagggccagc cactcggcac
    98821 cattcatcgg cggcatattg agttcaacgc cactttgttc cggcaacggc gggagcgttt
    98881 tactgtctgc cgcccaaata gcacgatcga gcgtcagctt ttgaccaagc aaccagcggc
    98941 tattgaaatg gttatccgca ccagcctgtc cggttaattc aaagctgttg agattgccat
    99001 caaccttaac gtttaccgct agtggttcac ccgcaggttt ggctaacggt gaaggtaagt
    99061 gactactcac attattcaga tcgccgttca tctctacgtt ataggtcgcg ccagcatgat
    99121 aaggcagatc aatgcccact ttaccatccc acgccacgct gccactcaat gcttcgttca
    99181 ccgcttcagg cagaacgccg gttttcgccg gttgccagtt accgttgagg tttaccgcta
    99241 cctggtaggc ttttgcccct tctttggtgg aaaaatccac gttcaacggc tgattaaacc
    99301 agcttgctgt cagtggttca ctttgcagat cgccattgat aaagctgaat ttaccgctca
    99361 aatttttcag ggtgctgtcg agtggtttga taaacagact gttattacgc agcgtcactt
    99421 cacctttcgc ggttaccaac tcgccgttca gcgggatatc aagatgtaag cgagcattca
    99481 catcgccgtc gagctggagt tcttgcaggg tcgcacccag ggaatctttc agcggtgtct
    99541 catcaaagta agggcctacg gctttacccg gacctttaat gtcagcgtca atcagcagtt
    99601 tttcttttga gtagtcaggg atcactgcgg tgagattact cgcgcgcacg ccgcccagat
    99661 taacgccatc ggttttcatc cataaaccgt cgttaataaa gtccagttca atatcaaggt
    99721 tagttaatgc aggccagtcc ggctggaagg caaacttcgc gttgcgcagc ggcaccagca
    99781 cttcaaactg accttcgttg tgtttatagg ggaagagttg cggattgcca ccataaacca
    99841 gcgtcgcgtt atccgcttca ccgccctgaa tcgcgccact taagtaatca accaggtctt
    99901 tacccatcaa gttttccggg aaatagcgcc aggcttgtga accatcatcg gtactgatgc
    99961 cagccagaat acccagccag ggttcatcgt tagcaggttg caggtaacga aaaccgccgc
   100021 gcgcatggac ggctttggct ttaacgtcaa tattacgccc atccagctgg aaacctttgt
   100081 cattgttcag ccagcttata gttgcctggc cgtcggcgat ttccagtggc gcacggaata
   100141 ccgtttcgta aggcatcttt gcctgcttca tcgacgcggt aagcaaacca ttttcaacgc
   100201 tgccggaaag cgtcccggag aagtgttccg cacccggtaa taatttccat tgcttccagg
   100261 ccagatcgct ccacgatgcc tgaaaacggg tattgtctgc cgcctgaagc gggatatcca
   100321 gcgccagagt gttaatcttg ccgctcggtt gtgtggagcg ccaaacatca cccagtgcag
   100381 gtgaaagttt cgcggccagc gggcgtatgc cctccaggcc tgccagctcc agattactgg
   100441 cgcgaatccg gagttcgtca ctgcgtttat tgtctttgcc gccaacgtcc tgttccggta
   100501 tccaggccag cgtcaatgct ccgctcggcc agggtttacc gtccatcgtg atccgtgtat
   100561 cgggaataga gaactgccag cccggatttt cacgcgtaat atgcgcggtc agattatcca
   100621 ccgacagcgt atgcgtttcc ttctcgccca accagctggc accgccctgt ttcagccaga
   100681 cgtcaccgcc ggttacatcg cctttgtcga tcgtcatcca gccttcaagg gagaactgtg
   100741 ccgtttccag agcaatattg tcctgcatcc atttaccgag ccacggcttc aggtcgatgt
   100801 catccgcctg tagccagacg cgaccattgc ttaacaaccc ctcatcatcg cgcaaatcca
   100861 tgcgcacctg catcacgccg tgctgtccgg taaggctgga gaggcttacc aggccttccg
   100921 cacggtgtcg acgtggatcg ttcagccagg tgagttgtgg gatcgccagc tcggcgcgct
   100981 gaccggatgg cgtcagaaaa ctgacttcac tgtcgcggag atcgaaatgg tcaaattgac
   101041 gaagaaacag atcgctgatg tgactggctt ccagactgtc atcgctacca ccgctggtga
   101101 taggagtgtt ggtgcgaaag cgcagctgcc agaaagtgag gtcgcgaaac tgccagcgca
   101161 tatgtaacag gctctgccag acatccagcg ccagagtaac gcgtttaacc gaaaattcgc
   101221 cgccatcttt tagttctgca cggatgtcgt gtgcttcaag cgtcgggcca aaattctgcc
   101281 agctggctga gagctgactg gcttctaccg gcatgccagt cgcggattct attttgttga
   101341 ggatttccgg acgccaggcg tcaagatgcg gtaaagcaat acgcaggccg ctaaccagca
   101401 gggctgcgat cacaacgagc gcggctccag taagcagtaa aatccccggc aatcgcctca
   101461 cccgtcactc cttgtctgct aaaaatgtga ctcaaaaacc ctttgccgga tggcggccca
   101521 gcatctgttt acatcattac gacgtcaaac tgctcctggt tatagagcgg ttcaatttgt
   101581 actttaacct gtttaccaac gaaaatttcc acttccgcca gcgagtgtga ctcttcgcct
   101641 ttcaaggctt cagctactgc cggagaagca tagaccagga aacggtcgga gtcgtaagca
   101701 tggtggacac gaacaatctc gcgcatgatt tcatagcata ccgtttccac ggttttcacc
   101761 gttccgcgac cgtggcaggt tgggcattcg ttacacagta cgtgctcaat gctttcgcgg
   101821 gtgcgtttac gcgtcatctc caccagcccc agcgccgaaa aaccattaac gctggttttc
   101881 acccggtctt tgctcaacgc ctgctccagc gagtgcagca cgcggcggcg gtgatcttca
   101941 ttattcatat cgatgaaatc aataatgata atcccaccca gattacgcaa ccgtaactgg
   102001 cgagcgatag cctgcgtcgc ttcaatattg gtattgaaaa tggtgtcgtc cagattgcga
   102061 tgaccgacaa acgctccggt attgatgtcc acggtggtca tcgcttcggt ctggtcgata
   102121 atcagataac caccggattt cagttctact ttgcgttcca gcgctcgctg gatttcgttt
   102181 tcgacatcaa agagatcgaa aatcggctgg cgtccggtgt aatgctccag cttgctggtc
   102241 atctcgggaa tgtactccga ggtaaactcc agcaatgctt cgtaagtcag gcgtgagtca
   102301 acgcgaatgc ggtccagttc ggcgtcggcg aaatcacgca gaacacgctg cgccagcgcc
   102361 agttcgccgt acagctgata acgggtctgc gggcgttttt tacgctccat aactttggtc
   102421 cagacgcgtt tcagataagc ggcatcggag gccagttcag cctcgccaac cccttccgct
   102481 gcggtacgga tgataaaccc gccctgctcg tcgcaatact ctgcgaccac ttttttcagg
   102541 cgttcacgtt ctgattcgct ttcaatacgt tgggaaacac caacgtgaga agcccctggc
   102601 ataaagacca gatagcgaga aggcagcgtg atatcggtgg tcaggcgcgc ccccttagtg
   102661 ccaagcggat ctttcaccac ctgcaccatc agatcttgcc cctgacgaac cagttccgag
   102721 atgtcgcgca ccgtgaattg cttttgttct tcacccgcca cacattcggt gtgcggcatg
   102781 atatcggatg catgaagaaa cgcggcttta tccagcccaa tatctacaaa agccgcctgc
   102841 atacccggaa gtacacgact tacacgaccc ttgtagatat tgcctactat tccgcgtcgc
   102901 gcctcacgtt caatatgaat ttcctgcaga ataccgccat caatatacgc cactcgcgtt
   102961 tccgaaggcg ttacgtttac taacaattca gccgtcatgt ttatcccttt tctcacgcag
   103021 tgcgttaaaa ttacttaata attcatacgt ttcaaccagc ggtaagccga ctacggcgtg
   103081 atagctgcca tttatcttcc tgacaaaaca gccacccagc ccctgaatac cgtatgcacc
   103141 tgctttatct aacggttcac cgctggcgac atagcccgcg atgtcttcgt ctgttaacgt
   103201 tctgaaagtc acatcggtga ccaccaggca atcgagaatg tgctggctgt cggccaacgc
   103261 cactgccgtc atcacctgat gggtctgacc cgataatttg cgcaacatct gcgccgcatg
   103321 ctctgcgtcg cgcggtttct ccagcacttc tccattcagg ataacgatag tatccgcacc
   103381 cagcaccggg agatcctgcg ccgtttgcgc gacacccgcc tgtgctttct cgcgcgccag
   103441 acgcacaaca tactgctgcg cgctctcctg cggctgacgc tgctcctcaa tgcccgtaac
   103501 aatacgttca aaggtcacgc caagttgcgc aagtaactcc tgacgacgcg gagaaccgga
   103561 agctaaatac agagaagtca tagaaacctt tattgcactg caaactgctg acggacttta
   103621 cgcatcagca agaaaatcca cggccagagc accccattga ctacactact ccagaacact
   103681 tccggtctga aagagacgtt aatcactaaa aactctgccc agaaaacaat aatatccacc
   103741 accagcgaaa gcaacatgac gaccagcgcc tgctgccata atgcgaggtt gcggaaaagc
   103801 tggtatttca gcgccaccag gtaagcaatg atgctcatcg ccaatacgcg tacgccaagc
   103861 gtcgagccgc tgatcagatc cagtatggca cccatcacaa aacctgtgcc cacatttacg
   103921 cgatgaggca aggccaggat ccaatacaac aagatgagta acacccagtt tggccggaaa
   103981 acaatcaggt tatccggcca gggcatgatt tgcagcaaca gcgcaatgag gaaagagagc
   104041 cagattaccc aacgtccctg gctacgatag ctcgccacta ttgccctccc ggcgcacgcg
   104101 caggcggttg agcaccactt tgcggcggcg tagccctttg tggagagcgg ttagcagcag
   104161 gctgtgtcgg cgcagcaggc gcagtagctg catttcctgt cgtcggttgc tgcggagtcg
   104221 gctgagcgat ccccgttgcc ggttcaggta actttggccc catcgcgtct ggcgaaggca
   104281 atacctgcgg catcatctgc atcagacgtt cattagcaac acgatgcacc tcttccggcg
   104341 tcatcgggtt agcgccgtta cgatccgcgc cccacagcag cagcagataa cgcaaacgtt
   104401 gcagccctgc tgtcggacgc gcctgaatca cagtataagc gcgctgggta tcgagtttta
   104461 cggaagagac aaccgcgacc ggatagcctt ccgggaaacg accgcccaga ccggaagtca
   104521 ccagcacatc accaacacga atatccgtat tcactggtag atgctcaagc tgcaaatcat
   104581 ccgtacaacc gttaccggct gcaattacgc ggatatcgtt gcgcagcacc tggattggca
   104641 gcgcgtgggt cgcatcacaa atcagcagca cgcgactggt cagtttagcg acggccacca
   104701 cctgaccaac aacacctttg tcgctgatga ccggctggcc ttcataaacg ccattaacgc
   104761 tacctttatc gataacaact tgatcgctat aaggatcgtt aaccgtggag ataacctgag
   104821 tcaccatttt ctgctcatcc tgacgcagcg gggaacccag cagctcgcgc agacgcgcgt
   104881 tctcctgttt gtattgtcca agcatcagca gttcactgtt tttcagcaac agttcctgac
   104941 gtaacgcccg gttttcaagt tctagttggt cacgcgaggc cagcgtctgc gatacgccat
   105001 ccagcaattc acgaggagca ttggaaacaa agtagaaagg actgacggcg gtatccatat
   105061 aagtacggat ttgactgaac gtccccaggc ggctgtcggc aataataatg ccgagcgcca
   105121 ccagcaccgc cagaataagg cgaatctgta gcgacgggcc acggctaaaa attggcttca
   105181 taagttatgc gtattctcgt atcagaccag gcagggtaaa cagacatttc ccctgcctgc
   105241 atccgattac tcttcgctga acaggtcgcc gccgtgcatg tcgatcattt ccagcgcttt
   105301 gccgccaccg cgcgccacac aggtcagcgg gtcttcagca acaacgactg gaatgccggt
   105361 ttcttccatt aacaaacggt caaggttacg cagcagtgcg ccaccaccgg tgagcaccat
   105421 gccgcgctcg gagatgtcgg aagccagttc cggcgggcac tgttccagtg caaccattac
   105481 cgcgctcaca ataccggtca gcggttcctg cagtgcttcg aggatttcgt tggagttcag
   105541 ggtaaaaccg cgtggaacac cttctgccag gttacggcca cgaacttcga tttcacggac
   105601 ttcatcgccc gggtaagccg aaccgatttc gtgcttgata cgttctgcgg tggcttcacc
   105661 gatcagagaa ccgtaattac gacgcacata gttgatgata gcttcgtcga aacgatcacc
   105721 accaatgcgc acggaagagg agtaaaccac gccgttcaag gagataacag caacttcagt
   105781 ggtaccacca ccgatatcaa ccaccataga accggtcgct tcagaaaccg gcaggccagc
   105841 accaattgcg gcagccatcg gttcttcaat caggaagact tcacgggcac cagcgccctg
   105901 cgcggattca cgaattgcgc ggcgttcaac ctgggtcgcg ccaaccggta cacaaaccag
   105961 aacgcgcggg cttggacgca taaagctgtt gctgtgcact tgtttgatga agtgctggag
   106021 cattttttca gtcacgaaga agtcggcgat aacgccgtct ttcattgggc gaatggcagc
   106081 aatattgccc ggcgtacggc ccagcatctg cttcgcgtca tgacctactg cagctacgct
   106141 tttcggtgaa ccggcacgat cctgacgaat ggccaccacg gaaggctcat tcaatacgat
   106201 gccttgtcct tttacataaa tgagggtatt cgcagtaccc aggtcaatgg acaagtcatt
   106261 ggaaaacatg ccacgaaatt ttttcaacat actaagggat aatcctgaaa gctggggcgg
   106321 aaaagaaaat ccgcttactt taccaaccac acgcagcagc gacaaggcgc aaaaatcatc
   106381 tgctacggtg aaaattagtg cagttcgttt cctttgttac aaatctctgc ctgagtccag
   106441 aaaggcttaa tgcatcagca gcattcctcg cctgtttgca accgcgtaag gtcattcatc
   106501 tgcatatgtg ctgcaacaat ctggcgagca gacaagcaca ctcccatgag acgcagcgcg
   106561 cgttattcta cgtgaaaaca gattaaacgg caggttaaac cgagtatctt tgtgaatatt
   106621 ttttcacgtt agtatcaagt ggctgtgagg acgcgaaaaa atccccttgc ccgcctgtaa
   106681 caccgcgctg aatcagggtc tgccactcgc ttcgcgaacg cacaccggtg gcgtaaactt
   106741 gggtgctggt cccggagcag gcttccacca ggctttgaac cagcagctgg ttctccgttc
   106801 gcttctcaat gtttctgacc agccccggat ggagcttgag taactcaaca ttaagttctt
   106861 tgatccaact ggtgcttacc agcgtcaaac cagcctggtt gacggctacc cgtaccccta
   106921 aagcattcac taaacgaata acaggttgta aacgactgat atgttgacct acatcggcct
   106981 ctgcaagttc aataattatg cgttttcgtt gtgatttttc acattgcatt aacgtatcgc
   107041 gcagccaacg ctgaaaacgc gggcgaatca gcgactcaac ggtaacctga atcgccagat
   107101 tttcctctgg ccagtaacgc aatagtggaa taagacggct gatttgcaga cggtcatact
   107161 cttccgataa gccaaactgc aagaccatcg gcatatactc cgccgagcta acctcttcat
   107221 taccatcgaa gatgcggcac atgagttcgc gatgatgaac ctgaccttcg cgagtaaccg
   107281 ccggtttttg ataaaggcgc gggccgccgc gactgagcat ttgctcgata agcgtacgcc
   107341 agcgaacatt accgcgtcct ttttcaggca acgagtcatc gtaaatagcc cagctattgc
   107401 cgccctgcaa tcccgcatta cgcgtggcag actctgcatg ttccattacc tgctcggtat
   107461 cctgaccact acgccaggcg cagataccaa tgtggatcat atcgtcgcga tcgagcattt
   107521 tattgttcgg caaggtatcg acggctttga ttaactgacc ggcgatgctc tctgcctctt
   107581 ttaacgtccg gtgcggtaac agcgcagcaa aatcactgcg gtggtaacgc gccagcagtg
   107641 cgccagggta gcgcatcata aatgtcgaca gcagattcgt cagagtgaag aactgttctt
   107701 caacctggct gtgcccccag gtatcgctca acatattgaa atccggcaga cgaatcatca
   107761 tcacgatccc gtgggtacct actttctcct gatcttccag taacgttgct aactgattat
   107821 cgaaaaagag tcggttattg aggccggttt tcacgtcctg ggcggcataa gagcggatca
   107881 gcgtatcaag acggctgtgt tgttcgcgtg cgttctgaat ttcacgaagc agcgtatcta
   107941 gcgcactgct ggttctgggc ggccattcat agatggttcc caacacatta gagccacgct
   108001 caccgtttaa gatacgagta gcccgggttt ccagcaattc ttgcccggca agttgccgtt
   108061 gtaaccagcg taccgccagg aagagcataa caatgataaa gccaatcgcc cccgtgagcg
   108121 gcgcggtagt cattaaagaa tggaaatagt tgcccatcgg atcctgataa accagacgca
   108181 gcgacatccc cggatgcttt atcaacggaa cactcagttc gcgaaacaga tcgctggagc
   108241 caaccggacg ataactacca tttctggcca gggtataaac ctgtttatca ccatggagca
   108301 ggtctacacg aacgatatct gccgacatca ttaattcggt aatttgtggc cttaatgtgc
   108361 tgaagtcatt cgacacaagg tgggtatcaa tcgccgtcgc caccgcctga acgcgatgac
   108421 taaacttata ctgaattgcg ttgtagaaac ttagcgaaca gcccagcaaa gtcacaaaaa
   108481 ttgttaaccc ggtgagcagc gtaacaaagg ccgaaaattt cgtcgttaat ctcatccttg
   108541 tgttaactcc gatagtgagg aagcgggcat actagcaaat cagatttatc tcgcaattta
   108601 ttgcgcttca tcggctttgc ttttccatta gcgagtatag tcttcagaaa ttattttcca
   108661 atccatcatg cacatgagga ccacttatgc aggcgttact tttagaacag caggacggca
   108721 aaactctcgc atcggtacag acacttgacg aaagtcgcct gccggagggc gatgtcacgg
   108781 ttgatgttca ctggtcgagc ctgaactata aagatgcgct ggcgattacc ggtaagggaa
   108841 aaatcatccg taattttccg atgattcctg ggatcgattt tgccggaact gtacgcacca
   108901 gcgaagatcc gcgttttcat gccggtcagg aggtgttact cactggctgg ggcgttggtg
   108961 aaaaccactg gggtgggctg gcggagcagg cgcgagtgaa aggtgactgg ctggttgcca
   109021 tgccgcaagg gctggacgcg cgtaaagcaa tgattatcgg tactgccggt tttaccgcca
   109081 tgctgtgtgt gatggcgctg gaagatgccg gtgttcgccc gcaggacggg gagattgtcg
   109141 tgacgggtgc cagtggtggc gtcggcagta ccgccgtggc gctgctgcat aagttgggtt
   109201 atcaggtcgt tgccgtttcc ggtcgcgaaa gtacccatga atacctgaaa agtttaggtg
   109261 ccagtcgtat tctccctcgt gatgagtttg ccgaatcccg tcctctggaa aaacaagtct
   109321 gggctggggc aattgacact gttggcgaca aagtgctggc aaaagtgctg gcgcaaatga
   109381 attacggcgg ctgcgtggcg gcctgtggtc tggcgggtgg ttttactctg ccaaccacgg
   109441 tcatgccatt tattctgcgt aatgtccgtt tgcaaggggt ggattcagta atgacgccac
   109501 cagaacgccg cgcacaagcc tggcagcgac tggtcgccga tttaccggaa tcattctata
   109561 cccaggcggc aaaagagata tctctgtcag aggcaccgaa ctttgccgag gccatcatta
   109621 ataaccagat ccagggtcgc acgctggtga aggttaacta accatttagc aaggaataat
   109681 aagagaggga actcattttg acatcattat tcaatcggtt aacgggaaaa gcggttagcc
   109741 ggacagcttt cgtcgaacac cttggtcagg aagttgtaca acatcatcca aactggaaag
   109801 tcatgatttc gactgaccac aaattgatgc gcattgatac tcctctaaac agccattatt
   109861 gatatgcctc cgtcgcctgt taggtttatg gtgctttgcc tgggcgacac tacgcttaac
   109921 ctattactga tttctggtcc catggggtga ataatctgat tttatttgac tacaaattaa
   109981 ccactcgaac ctatttaatg ctgagcattg tcagtcggtt gattttgcgt gctttagcat
   110041 tcacatctat ccagacgatg cagtgaaaat tgggtaatcc ccagcaaccg ctgcgtaatg
   110101 tcgtctatct tgtcgcgatc ctggcatccc tacattattt gtggtctgtg aagattatct
   110161 cattgcagcc cctcatcttc gcagggctgg ctttacagct tttcacctta cgttataaga
   110221 agttccgtcg atgatggcgc taatttcgtg aattgtgcgg cttgttgcaa attacacggt
   110281 gttgaaggtt atttacatgt tagctgttga ttatcttccc tgataagacc agtatttagc
   110341 tgccaattgc tacgaaatcg ttataatgtg cgacctcgtc ctccctgaca cagtttttgc
   110401 gctgcggaaa aggtgacatt ggcgcaacga aggtatattt tgttttttgc cggaggatag
   110461 cagcagatcg ctgcacaatg tccgtcaagt ctaacattga cactctgggg caaaatagac
   110521 cggcgtcccg gcctgctgga atttatcgct atgcatacag ctgtcggggc atacgcttta
   110581 cagacggcgg tgaaacgcct gtcacaatca cactaaacaa agagtacgga acccactcat
   110641 ggatattcgt aagattaaaa aactgatcga gctggttgaa gaatcaggca tctccgaact
   110701 ggaaatctcc gaaggcgaag agtcagtacg catcagccgt gcagctcctg ccgcaagttt
   110761 ccctgtgatg caacaagctt acgctgcacc aatgatgcag cagccagctc aatctaacgc
   110821 agccgctccg gcgaccgttc cttccatgga agcgccagca gcagcggaaa tcagtggtca
   110881 catcgtacgt tccccgatgg ttggtacttt ctaccgcacc ccaagcccgg acgcaaaagc
   110941 gttcatcgaa gtgggtcaga aagtcaacgt gggcgatacc ctgtgcatcg ttgaagccat
   111001 gaaaatgatg aaccagatcg aagcggacaa atccggtacc gtgaaagcaa ttctggtcga
   111061 aagtggacaa ccggtagaat ttgacgagcc gctggtcgtc atcgagtaac gaggcgaaca
   111121 tgctggataa aattgttatt gccaaccgcg gcgagattgc attgcgtatt cttcgtgcct
   111181 gtaaagaact gggcatcaag actgtcgctg tgcactccag cgcggatcgc gatctaaaac
   111241 acgtattact ggcagatgaa acggtctgta ttggccctgc tccgtcagta aaaagttatc
   111301 tgaacatccc ggcaatcata agcgccgctg aaatcaccgg cgcagtagca atccatccgg
   111361 gttacggctt cctctccgag aacgccaact ttgccgagca ggttgaacgc tccggcttta
   111421 tcttcattgg cccgaaagca gacactattc gcctgatggg tgacaaagtg tcggcaatcg
   111481 cggcgatgaa aaaagcgggc gttccttgcg taccaggttc tgacggcccg ctgggcgacg
   111541 atatggataa aaaccgtgcc attgctaaac gcataggtta tccggtgatt atcaaagcct
   111601 ccggcggcgg cggcggtcgt ggtatgcgtg tagtgcgcgg cgacgctgaa ctggcacaat
   111661 ccatctccat gacccgtgcg gaagcgaaag ccgcattcaa taacgatatg gtttacatgg
   111721 agaaatacct ggaaaatcct cgccacgtcg agattcaggt actggctgac ggtcagggca
   111781 acgctatcta tctggcggaa cgtgactgct ctatgcagcg tcgtcaccag aaagtggtcg
   111841 aagaagcacc agcaccggga attacaccgg aactgcgtcg ctacatcggc gaacgttgtg
   111901 ctaaagcgtg tgttgatatc ggctatcgcg gtgcaggtac tttcgagttc ctgttcgaaa
   111961 acggcgagtt ctatttcatc gaaatgaaca cccgtattca ggtagaacac ccggttacag
   112021 aaatgatcac cggcgttgac ctgatcaaag aacagctgcg tatcgctgcc ggtcaaccgc
   112081 tgtcgatcaa gcaagaagaa gttcacgttc gcggccatgc ggtggaatgt cgtatcaacg
   112141 ccgaagatcc gaacaccttc ctgccaagcc caggcaaaat cacccgtttc cacgcacctg
   112201 gcggttttgg agtgcgttgg gagtctcata tctacgcggg ctacaccgta ccgccgtact
   112261 atgactcaat gatcggtaag ctgatttgct acggtgaaaa ccgtgacgtg gcgattgctc
   112321 gcatgaagaa tgcgctgcag gagctgatca tcgacggtat caaaaccaac gttgatctgc
   112381 agatccgcat catgaatgac gagaacttcc agcatggtgg cactaacatc cactatctgg
   112441 agaaaaaact cggtcttcag gaaaaataag actgcaaaag cgtcaaaagg ccggattttc
   112501 cggccttttt tattactggg gatcgacaac ccccataagg tacaatcctc gctttcttca
   112561 cccatcaggg acaaaaaatg gacactcgtt ttgttcaggc ccataaagag gcgcgctggg
   112621 cgctggggct gacccttttg tatctggcag tttggttagt agccgcttac ttacctggcg
   112681 ttgcccccgg ttttaccggc tttccgcgct ggtttgagat ggcctgcatc ctgacgccgc
   112741 tactgtttat tggactgtgc tgggcgatgg tgaaatttat ctatcgcgat atcccactgg
   112801 aggatgacga tgcagcttga agtaattcta ccgctggtcg cctatctggt ggtggtgttc
   112861 ggtatctcgg tttatgcgat gcgtaaacgg agcaccggca ccttccttaa tgagtatttc
   112921 ctcggcagcc gctctatggg cggtattgtg ctggcgatga cgctcaccgc gacctatatc
   112981 agtgccagtt cgtttatcgg cgggccagga gctgcttata aatacgggct gggctgggta
   113041 ttgctggcga tgattcagct tcctgcagtc tggctttcac tcggtattct cggcaagaag
   113101 tttgcgattc ttgcgcgccg ctacaatgca gtgacgctga acgatatgct gtttgcccgc
   113161 taccagagtc gtcttctggt gtggctggcg agtttgagtt tgctggttgc gttcgttggt
   113221 gcgatgaccg tgcagtttat cggcggtgcg cgcctgctgg aaaccgcggc gggtattcct
   113281 tatgaaaccg ggctgctgat ttttggtatc agcattgcgt tatataccgc ctttggtggc
   113341 tttcgcgcca gcgtgctgaa cgacaccatg caagggcttg tgatgctgat tggcaccgtt
   113401 gtgctgctta ttggcgtggt acatgccgct ggcggcttaa gcaacgcagt acagaccttg
   113461 caaaccatcg atccgcaact ggttacgcca caaggcgctg acgatattct gtcgcctgcc
   113521 tttatgacgt cgttctgggt actggtgtgc tttggcgtga ttggcctgcc gcatactgcg
   113581 gtgcgctgta tctcttataa agacagcaaa gcagtacacc gggggatcat catcggtacg
   113641 attgtagtcg caatcctgat gttcggtatg cacctggccg gagcgttagg tcgtgcagtg
   113701 atccccgatc tcaccgtacc ggatctggtg atcccgacgt taatggtaaa agtgctgcca
   113761 ccgtttgctg ccggaatctt cctggctgca cctatggctg cgatcatgtc gacgatcaat
   113821 gcccagttgc tgcaaagttc cgctacgatc attaaagatc tctatctgaa tatccgtccg
   113881 gatcaaatgc aaaacgagac gcgtctgaag cggatgtcgg cggtaattac gttagttctc
   113941 ggcgcgttgc tgctgcttgc cgcctggaag ccgccagaaa tgatcatctg gctgaatttg
   114001 ctggccttcg gtgggctgga agccgttttc ctgtggccgc tggtgctggg tctttactgg
   114061 gaacgcgcca acgccaaagg cgcgctaagt gcgatgatcg ttggcggcgt gctgtatgcc
   114121 gtactcgcga cgctgaatat tcagtacctg ggcttccacc ctattgtgcc ctcgttacta
   114181 ctaagtttgc tggctttcct ggtcggaaac cgtttcggta catccgtccc gcaagctacc
   114241 gttttgacta ctgataaata aagagttttg ccatgccttg gatccaactg aaactgaaca
   114301 ccaccggcgc gaacgcggaa gatcttagcg atgcgctgat ggaagcgggt gccgtttcta
   114361 tcacttttca ggatacccac gatacgccag tatttgagcc gctgccgggc gaaacgcgcc
   114421 tgtggggcga caccgatgtg attggtctgt tcgacgctga aaccgatatg aacgacgtgg
   114481 tggcgattct ggaaaaccat ccgctgctcg gcgcaggctt cgcgcataaa atcgaacaac
   114541 tagaagataa agactgggag cgcgaatgga tggataattt ccacccgatg cgctttggtg
   114601 aacgactgtg gatctgccct agctggcgtg atgtgccgga cgaaaacgcc gtcaacgtga
   114661 tgttagatcc agggctggcg tttggtacgg gtacccatcc aaccacctct ctgtgcctgc
   114721 aatggctcga cagcctcgat ttaaccggta aaacagtcat cgactttggc tgtggttccg
   114781 gcattctggc gatcgcggcg ctgaaactgg gtgcagcaaa agccattggt attgatatcg
   114841 atccgcaggc gattcaggcc agccgcgaca acgccgaacg taatggcgtt tctgaccgtc
   114901 tggaactcta cttaccgaaa gatcagccag aagaaatgaa agccgacgtg gtggtcgcta
   114961 acatccttgc aggcccatta cgtgaactgg caccgttaat cagcgtcctg ccggtttcag
   115021 gcggtttgct gggcctttcc ggtattctgg caagccaggc agagagcgtt tgtgaagctt
   115081 atgccgatag cttcgcactg gacccggtcg tggaaaaaga agagtggtgc cgtattaccg
   115141 gtcgtaagaa ttaaccttcg catcgccgta gggtgacgcg gggcgaagtg cgagcaagct
   115201 cacaaaaggc acgtaaattt gccggttatt tacgcaaatt tgcgtgccaa aattttcatt
   115261 cataaagaaa aattgagaac ttactcaaat ttctttgagt gtaaatttta gtcactattt
   115321 tctaatatga tgatttttat gagtaattat cgcaccacgc tcattttaaa tgcaattctt
   115381 tgatccatct cagaggattg gtcaaagttt ggcctttcat ctcgtgcaaa aaatgcgtaa
   115441 tatacgccgc cttgcagtca cagtatggtc atttcttaac tcatgcgcat cggacaatat
   115501 cagctcagaa atcgcctgat cgcagcgccc atggctggca ttacagacag accttttcgg
   115561 acgttgtgct acgagatggg agccggattg acagtatccg agatgatgtc ttctaaccca
   115621 caggtttggg aaagcgacaa atctcgttta cggatggtgc acattgatga acccggtatt
   115681 cgcaccgtgc aaattgctgg tagcgatccg aaagaaatgg cagatgcagc acgtattaac
   115741 gtggaaagcg gtgcccagat tattgatatc aatatgggtt gcccggctaa aaaagtgaat
   115801 cgcaagctcg caggttcagc cctcttgcag tacccggatg tcgttaaatc gatccttacc
   115861 gaggtcgtca atgcagtgga cgttcctgtt accctgaaga ttcgcaccgg ctgggcaccg
   115921 gaacaccgta actgcgaaga gattgcccaa ctggctgaag actgtggcat tcaggctctg
   115981 accattcatg gccgtacacg cgcctgtttg ttcaatggag aagctgagta cgacagtatt
   116041 cgggcagtta agcagaaagt ttccattccg gttatcgcga atggcgacat tactgacccg
   116101 cttaaagcca gagctgtgct cgactataca ggggcggatg ccctgatgat aggccgcgca
   116161 gctcagggaa gaccctggat ctttcgggaa atccagcatt atctggacac tggggagttg
   116221 ctgcccccgc tgcctttggc agaggttaag cgcttgcttt gcgcgcacgt tcgggaactg
   116281 catgactttt atggtccggc aaaagggtac cgaattgcac gtaaacacgt ttcctggtat
   116341 ctccaggaac acgctccaaa tgaccagttt cggcgcacat tcaacgccat tgaggatgcc
   116401 agcgaacagc tggaggcgtt ggaggcatac ttcgaaaatt ttgcgtaaac agaaataaag
   116461 agctgacaga actatgttcg aacaacgcgt aaattctgac gtactgaccg tttctaccgt
   116521 taactctcag gatcaggtaa cccaaaaacc cctgcgtgac tcggttaaac aggcactgaa
   116581 gaactatttt gctcaactga atggtcagga tgtgaatgac ctctatgagc tggtactggc
   116641 tgaagtagaa cagcccctgt tggacatggt gatgcaatac acccgtggta accagacccg
   116701 tgctgcgctg atgatgggca tcaaccgtgg tacgctgcgt aaaaaattga aaaaatacgg
   116761 catgaactaa ttcaggttag ctaaatgctt gattaaaaag gcgctactcg gcatggggaa
   116821 gcgccttttt tataggtgtc acaaagggag tgaccatgag aacaggatgt gaaccgaccc
   116881 ggtttggtaa tgaagctaag accattattc acggtgatgc gcttgccgaa cttaaaaaga
   116941 tccccgccga aagtgtcgat ctgatctttg ccgacccacc atataacatc ggtaaaaatt
   117001 ttgatggtct gatcgaagcc tggaaagaag atctgtttat cgactggctg tttgaagtga
   117061 ttgcagagtg ccaccgcgtt ctgaaaaagc agggcagcat gtacatcatg aacagcacgg
   117121 aaaacatgcc ctttatcgat ctccagtgcc gcaagctttt taccatcaaa agtcgcatcg
   117181 tctggtcata tgacagttct ggagtacagg cgaaaaaaca ctacggctcc atgtacgaac
   117241 ccatcctgat gatggtgaaa gacgcaaaga actacacatt caacggtgat gctattctgg
   117301 tagaagccaa aaccggatcg cagcgcgcgt tgatcgatta tcgcaaaaat cctccacagc
   117361 catacaatca tcaaaaagta ccgggtaacg tctgggattt tccgcgcgtg cgttatttga
   117421 tggatgaata tgagaaccac ccgacgcaaa aaccggaagc cttactgaaa cgcattattc
   117481 tcgcctcttc caacccaggc gatatcgttc tcgacccgtt tgccggtagc tttactaccg
   117541 gtgccgtagc cgtctccagc gggcgaaaat tcattggtat tgagatcaac agcgagtaca
   117601 tcaaaatggg gcttcgacgg ctggatgtcg cgtcgcatta ctctgcggaa gaactggcga
   117661 aagtgaaaaa aagaaagacc ggcaacctgt caaaacgaag ccggttaagc gaagttgacc
   117721 ccgatctcat tgcaaagtaa aggaagtgta agcctggttt tcagattatt catttcgtgt
   117781 atatttcctg ccagacttgg ttaaacatac acaggctcag gtaatgattc gcaagtattg
   117841 gtggctcgtc gttttcgctg tcttcgtttt tctgtttgat actttactga tgcagtggat
   117901 tgaactgctg gcaacagaaa cagacaaatg ccgcaatatg aactcagtta atccactaaa
   117961 actggttaac tgtgacgaac tgaattttca ggacagaata tgaatttaca tgacacttaa
   118021 ttcattcgtt tgatgaatta atttcgttat gttttcatct ggcatgaaca ttcttaatac
   118081 gttatcgacc agagcggggg cttgtttata aagatcataa cccgccatat tcattaacca
   118141 gttttgaaca attccgctga aggcaccatt aataataatc atcacaacat ctaaatcgag
   118201 gttatttgct acacaacctt gttgctgaca cgcctgcaat acttcgcgga gagtctgcgg
   118261 attgaagccc atcttttcgc gtatcactcc ctcggccagc atctcatcat taaattcaca
   118321 tttgtgatat aagattttca gcaacgcctg ctggcgggga attttggcaa tatattgcaa
   118381 gccgacaatc aatttttcac gcaattgttg aaacgggtca tgctctaatc cagccgtcaa
   118441 gtgttcctgg attaactccc gcaatgaagg ctgttgcaac cacatctcat taaacagttg
   118501 agtcttgttt tcgaagtgcc agtagatagc gccacgcgta acgttagcag cgtcggcaat
   118561 gtcgttgagt gtcgtcttgc ttacgccatg ctgcgcaaac tgggcgatgg cagtttcaat
   118621 cagttcttgc cgggtcttca gagcttcggc tttggttctt tttgccatga ttaattattc
   118681 aggaaataaa tatattcgac acagagtgag aaaatagcga aggttaatct atcacctaat
   118741 gtgtatttat acgagaggct aatattgagt tgctataaat cgtcaaataa ataatatata
   118801 ttatttacct aaaatacatt cgccacatga atatatattt caatttacga ggttttaatt
   118861 ctgcctcttt caacccgcgt caaaataaaa cagtagaata ttaatctttt tttgtgttta
   118921 tgtgccttga gacgccagta ttcataacta ttccttacat cgacgaatga taatttgtag
   118981 gatagcaaac tgtatttttc tttctgcgag ttaacgcgtt gcctttctgg gtaaataacg
   119041 cgcttttggt tttttgagga atagtaatga cgaaacatgc caggtttttc ctcctgccct
   119101 cctttattct gatctccgcg gctttaatcg ccggttgtaa cgataaggga gaagagaaag
   119161 ctcacgtcgg tgaaccgcag gttaccgttc atattgtgaa aacggccccg ttagaagtta
   119221 agactgaatt accaggccgc accaatgctt accgtatagc cgaagttcgc ccacaggtta
   119281 gcgggatcgt actgaatcgt aatttcactg aaggcagcga tgtacaagca ggccagtccc
   119341 tgtaccagat cgatcccgcg acctatcagg caaattatga cagcgcgaaa ggcgaactgg
   119401 cgaaaagtga agccgccgcc gccatcgcgc atttgacggt aaaacgttac gttccgctcg
   119461 tgggtacgaa atacatcagc cagcaggagt acgaccaggc cattgctgat gctcgccagg
   119521 ccgatgccgc cgtgattgcc gcaaaagcca cagtcgaaag cgctcgcatc aatctcgctt
   119581 ataccaaagt gactgcgcca attagcggac gtatcggcaa atcgaccgtg accgaaggcg
   119641 ctcttgtcac taatgggcaa acgactgaac tggcgactgt ccagcagctc gatcctatct
   119701 acgttgatgt gacccaatcc agcaacgatt ttatgaggct gaagcaatcc gtagagcaag
   119761 gaaatttgca taaggaaaac gccaccagca acgtagagtt ggtcatggaa aacggtcaaa
   119821 cctatcccct gaaaggtacg ctgcaattct ctgatgtgac cgttgatgaa agcaccggct
   119881 ccataaccct acgtgccgtc ttccctaacc cgcaacatac gcttttgccg ggtatgtttg
   119941 tgcgcgcacg gattgatgaa ggcgtccaac ctgacgccat tcttatcccg caacaaggcg
   120001 ttagccgcac accgcgtggt gatgcaaccg tgctgattgt taacgataaa agtcaggtgg
   120061 aagcgcgccc tgtcgttgcc agtcaggcga ttggcgataa atggttgatt agcgaaggtc
   120121 tgaaatctgg cgatcaagtc attgtcagcg gcctgcaaaa agcgcgtccg ggagagcagg
   120181 ttaaagccac taccgatacc cccgcagata ctgcatcgaa gtaaggtaat ctgacatggc
   120241 aaactttttt attcgacgac cgatatttgc atgggtgctg gccattattc tgatgatggc
   120301 gggcgcactg gcgatcctac aattacccgt cgctcagtat ccaaccattg caccgcctgc
   120361 ggtttctgtt tcagcaaact atccgggcgc tgatgcgcag accgtgcagg atacggtgac
   120421 gcaggttatc gaacagaata tgaacggtat cgataacctg atgtatatgt cctccaccag
   120481 cgattccgcc ggtagcgtga caattaccct taccttccag tccgggaccg atcctgatat
   120541 cgcgcaagtg caggtgcaga acaaactcca gctcgccacg ccgttgctgc cgcaggaggt
   120601 tcagcagcag gggatcagtg ttgaaaagtc cagtagcagc tatttgatgg tggcgggctt
   120661 tgtctctgat aacccagaca ccacacagga cgatatctcg gactatgtgg cctctaacgt
   120721 taaagatacg cttagccgtc tgaatggcgt cggtgacgta cagcttttcg gcgcacagta
   120781 tgcgatgcgt atctggctgg acgccgatct gctaaacaaa tataaactga caccggttga
   120841 tgtgattaac cagttgaagg tacagaacga tcagatcgct gccggacagt tgggcggaac
   120901 gccagcgtta ccagggcaac agttgaacgc ctcaattatt gctcagacgc ggttaaaaaa
   120961 tccggaagaa ttcggcaaag taaccctgcg cgtaaacagt gacggctcgg tggtacgcct
   121021 gaaagatgtc gcacgagttg aacttggcgg tgaaaactat aacgttatcg ctcgtatcaa
   121081 cggaaaaccg gcggcgggcc tggggattaa gctggcaacc ggcgcgaatg ctctcgatac
   121141 cgcgaaagcc attaaggcaa aactggcgga attacagcca ttcttcccgc agggaatgaa
   121201 ggttctctac ccttatgaca ccacgccatt cgtccagctt tctattcacg aagtggtaaa
   121261 aacgctgttt gaagccatta tgctggtgtt cctggtgatg tatctgttct tgcagaatat
   121321 gcgagcaacg ctgatcccca ccattgcggt acccgtggtg ttattaggga cgtttgccat
   121381 cctcgccgct tttggttact ccatcaacac actaacgatg ttcgggatgg tgcttgccat
   121441 cgggctgctc gtcgatgatg cgatagtggt ggtggagaac gtcgagcgcg tgatgatgga
   121501 ggataagctc ccgccaaaag aagcgacgga aaaatcaatg tcgcaaatcc agggcgcact
   121561 ggtgggtatc gcgatggtgc tgtcagcggt atttattccg atggcattct tcggcggttc
   121621 tactggggca atttatcgcc agttctctat caccatcgtt tcggcaatgg cgctttctgt
   121681 tctggtggca ttgattctta cccctgcgtt atgtgcaacg ctgcttaaac ccgtctctgc
   121741 tgagcatcac gaaaataagg gcggtttctt cggctggttt aatactacct tcgatcatag
   121801 cgttaaccac tacaccaaca gcgtcggcaa aatcctcggt tccacaggac gatatttact
   121861 gatctatgcg ctgattgttg caggaatggt ggtgttgttt ttacgtcttc cgtcttcctt
   121921 cttacctgaa gaggatcagg gtgtctttct gaccatgatt cagttacccg ctggcgcgac
   121981 gcaagagcgg acgcaaaaag tgttggatca agtgacggat tactatctga agaacgagaa
   122041 agcgaacgtt gaaagtgtct ttacggttaa cggctttagc ttcagcggcc aggcacaaaa
   122101 tgccggtatg gccttcgtca gtctgaaacc gtgggaagag cgtaatggtg atgaaaacag
   122161 tgcggaagcg gtaatccatc gtgccaaaat ggaatttggc aagatccgcg acggttttgt
   122221 cattccattc aatatgccag ccattgttga actgggcacg gcaacgggtt tcgactttga
   122281 gttaattgat caggctgggc tgggtcacga tgccctaacc caggcccgta accagttgct
   122341 tggtatggcg gcgcaacatc ctgccagctt agtcagcgtg cgtcctaatg gcctggaaga
   122401 caccgcgcag tttaaactgg aagttgacca ggaaaaggcg caggcattag gtgtttcact
   122461 ttctgacatc aatcagacca tttcaacggc gttgggtggg acttacgtta acgacttcat
   122521 cgaccgtggt cgcgtgaaaa aggtgtatgt tcaggcggat gccaaattcc gtatgctgcc
   122581 agaagatgtc gataaacttt atgtccgcag cgccaacggc gaaatggtgc cattctcggc
   122641 ctttaccact tcacattggg tgtatggctc tccgcgactg gaacgctaca acggtctgcc
   122701 gtcaatggag attcaggggg aagccgcgcc aggaaccagt tccggcgatg ccatggcgtt
   122761 gatggaaaac cttgcgtcaa aattacctgc tggcattggt tatgactgga cgggtatgtc
   122821 gtatcaggaa cgcttatcgg gaaaccaggc tcccgctctg gtagcaattt cctttgtggt
   122881 tgttttcctg tgccttgctg cactctatga aagctggtca attcctgtct cggttatgtt
   122941 ggtcgtgccg ttagggattg tcggcgtgct gctggcggcg acactcttta atcaaaaaaa
   123001 tgacgtctac tttatggtgg gcttgctaac gacaattggc ttgtcggcca aaaacgctat
   123061 tttgattgtt gagttcgcta aagatctcat ggagaaagag ggtaaaggtg ttgttgaagc
   123121 gacactaatg gcagtacgta tgcgtctgcg tcctatcctg atgacctctc tcgcctttat
   123181 tctcggcgta ttaccgctag ctatcagtaa cggtgccggc agtggcgcgc agaacgcagt
   123241 gggtatcggg gtaatgggcg gaatggtctc tgcaacgttg ctggcaatct tcttcgtacc
   123301 ggtgttcttt gtggtgatcc gccgttgctt taaaggataa atcagaaaca taaaggcact
   123361 ttcgggtgcc tttattattt tcagtgaaac ccataaaaat taataagata ttcttccact
   123421 cactctttaa aaactttcta tagttcccgc tcccttcact atttttacaa ttcacataat
   123481 ttgtcattat tcattccgca atatttataa cctccggtga taaaatggca ttcagctcgt
   123541 taataagaga gttaacttat taagcgttag cgtttattac tgaggtaaca ccatgaaaag
   123601 attaattcct gtggcattgc tcaccgcatt gctggcgggc tgtgctcacg attcgccctg
   123661 cgttccggtt tatgacgatc agggtcgtct ggttcacacc aatacctgta tgaaaggcac
   123721 gactcaggat aactgggaaa cggctggggc tattgccggc ggggcagcgg ctgttgctgg
   123781 cctgacgatg gggatcatcg ctctgtcgaa ataactgaac agggcgcgga gtttcgcgct
   123841 ctgtttaacg atacagtatc tttacataag ataaaatatt gctatattct gctggctaat
   123901 tctctgctga tttagcatgt tatatcgcgt tatttcgctg ctttcgaaat aacgcatcaa
   123961 tttaactttc acacttccca ccagaaatat actcacgcta acaatcatta ttctgcttag
   124021 taaaacacgc gtaaatattt tgcgccaaaa tgtggcgcat gtttcatttt cgcaccattg
   124081 cggggcgctg tttttattat ttcctgtcta cactcagctt attgcgacgc gaaatcgggc
   124141 gcaaaagctg gcactacttt tgcttataag aggatggcca cagacaggta aaagacgttt
   124201 cccaaacgtc ctataacgat aattttcgcc tcacaggaag cattatgaaa aagatgatga
   124261 tagccacact ggctgccgcc agcgtgctgc ttgccgttgc aaatcaggcg catgctggcg
   124321 cgacgcttga tgccgttcag aaaaaaggtt ttgtgcaatg cgggatcagt gatggattac
   124381 ctgggttctc ttatgccgat gcagacggta agttttcagg tattgatgtt gatgtttgtc
   124441 gtggtgttgc cgctgctgta tttggtgacg acacgaaagt gaaatatacc ccactcacag
   124501 caaaagaacg cttcacggct ttacagtcag gggaagtgga tttgctctcc cgtaatacga
   124561 cctggacttc atctcgcgac gccgggatgg gaatggcatt tactggcgtc acttattacg
   124621 acggcattgg cttcctgacg cacgataaag cggggctaaa aagcgcgaaa gaactggatg
   124681 gcgctaccgt ctgtattcag gcgggtactg ataccgaact caacgttgcc gactatttca
   124741 aggcaaacaa tatgaagtac acaccggtga ctttcgatcg ctctgacgaa tcagcgaagg
   124801 cactggaatc tggtcgctgc gatacgctgg cctcggatca gtcgcaactg tatgccctgc
   124861 gcatcaaatt aagcaaccca gctgaatgga ttgtcttacc ggaggttatc tctaaagaac
   124921 cgcttgggcc ggtagttcgt cgtggcgatg atgaatggtt ctcgattgta cgctggacgc
   124981 ttttcgccat gctgaatgct gaagagatgg gcatcaattc ccagaacgtc gatgaaaaag
   125041 cggctaatcc agcaacgcct gatatggcac atctgctggg taaagaaggc gattacggca
   125101 aggatctgaa gctggataat aaatgggcct ataacatcat caaacaggtg ggtaactact
   125161 cggaaatttt cgagcgtaac gtaggttcag aaagcccgct gaaaattaaa cgtgggcaaa
   125221 ataatctctg gaataacggc ggtattcagt acgcgccgcc cgtgcgttaa gtcggtgtga
   125281 ggtaacgggc gtcgctacgg cggcgctctc ttcagcgtta tgctttccga ggtttctatg
   125341 tctcatcgcc gctcaaccgt taaaggctca ctctcttttg ccaaccctac ggttcgcgcc
   125401 tggttattcc agatccttgc cgttgttgct gttgtcggca ttgttggttg gttatttcac
   125461 aacactgtaa cgaatctcaa taatcgtggc attacttcag gttttgcctt tctggatcgc
   125521 ggcgctggct tcggtattgt ccagcatttg atcgattacc agcagggcga cacctacgga
   125581 cgcgttttta ttgtcggctt actcaatacg ctactggttt ctgcattgtg tattgtgttc
   125641 gcttctgttt taggcttctt tatcggtctg gcgagacttt cggataactg gctgctacga
   125701 aaactatcca caatttatat tgagatcttc cgtaatattc ccccgctgct gcaaatcttc
   125761 ttctggtact ttgccgtgtt gcgcaatttg cccggaccac gccaggctgt gagcgcgttt
   125821 gatctggcct ttttgagcaa tcgtgggctt tatattccgt caccgcagct gggagacgga
   125881 tttattgcgt ttatcctggc tgttgttatg gctatagtcc tttctgttgg gctattccgc
   125941 tttaataaaa cataccagat aaagaccgga caactgcgcc gcacctggcc gatcgccgca
   126001 gtgttgatca ttggtttgcc tttactggcg caatggcttt ttggcgcagc actacactgg
   126061 gatgtcccag ccctacgagg ctttaacttc cgcggcggga tggttttaat tcctgaactg
   126121 gcagccttaa cgctggcact ttcggtttat acatctgcat ttatcgccga gattatccgc
   126181 gctgggatcc aggcagtgcc ttatggtcaa catgaagcgg ctcggtcact gggattaccc
   126241 aacccggtta cgctacgcca ggtcattatt ccccaggcac tgcgagtgat tattccgccg
   126301 ttaaccagcc agtatctcaa catcgtcaaa aactcctctc ttgccgccgc tattggctat
   126361 cccgatatgg tttcgctgtt tgctggcacc gtgctgaacc agacggggca agccatcgag
   126421 acgatagcca tgaccatgtc ggtctatctg attatcagcc tgactatctc gctgctgatg
   126481 aatatctata accgccgcat cgcgatcgtt gaacgctaag gagtcatgat gacaaaagta
   126541 ttgctgtctc agccctcgcg cccagcgagc cataactcaa gccgcgcgat ggtgtgggtg
   126601 cgaaaaaatc tgttctccag ctggagcaat agcctgctga ctattggctg catatggttg
   126661 atgtgggaac tgatcccacc gttgctgaac tgggcatttt tgcaggctaa ttgggttggc
   126721 tcaacgcgtg ccgactgcac aaaagccggt gcctgttggg tcttcatcca cgaacgattt
   126781 ggtcagttta tgtatggact ttacccacac gaccaacgct ggcgaattaa cctggcatta
   126841 ctgattggcc ttgtgtcaat cgcaccaatg ttctggaaaa tactcccgca tcgcggtcgc
   126901 tatattgcgg tctgggcggt gatttaccca ctgattgtct ggtggctgat gtatggcggt
   126961 ttttttggtc tggagcgggt tgaaacccgg caatggggcg ggctgacgct aactttaatt
   127021 attgcatccg ttgggattgc gggggcgcta ccgtggggga tcttactggc gttaggtcgc
   127081 cgctcccata tgccgattgt gcgtatctta tcggtcattt ttatcgagtt ctggcgcggc
   127141 gtaccgctga ttaccgtatt gtttatgtct tcggtcatgc tgcctttgtt tatggcagaa
   127201 ggcaccaata tcgacaaact gatccgcgcg ctggttggcg tgatcctgtt tcagtcagca
   127261 tatgttgcgg aagtcgtgcg aggcggatta caggcgctgc ctaaagggca atatgaagcg
   127321 gcagagtcgc tggcgttggg ttactggaaa actcaggggc tggttattct gccacaggcg
   127381 ttgaagctgg taattcctgg gctggtaaat accatcatcg cactcttcaa agataccagc
   127441 ctggtgatca ttatcgggtt gttcgatctt ttcagtagcg ttcagcaggc aaccgttgat
   127501 cccacctggt tgggtatgtc gacggaaggg tatgttttcg ccgcgctgat ctactggatc
   127561 ttctgtttca gcatgtcgcg ctatagccag catctggaaa aacgttttaa caccgggcgt
   127621 acaccgcatt gaggacacta tgagccaaat tttactgcaa cctgctaacg cgatgattac
   127681 gctggaaaac gtcaataaat ggtatggaca attccatgtt ttgaaaaata taaatttaac
   127741 cgtgcaaccg ggagaacgga tcgttctgtg tggcccttca ggttccggta aatcgacaac
   127801 cattcgttgt attaatcatc tggaagaaca tcaacaggga cggatcgtgg tagatggcat
   127861 cgaacttaat gaagatatcc gcaatattga gcgcgtccgg caggaagtgg gaatggtctt
   127921 tcagcatttc aatctcttcc ctcatctgac cgttctacag aactgtaccc tggcaccgat
   127981 ttgggtacgc aagatgccaa agaaagaggc tgaagctctg gcgatgcatt accttgagcg
   128041 ggtgagaatt gccgaacatg cgcataagtt tcccggacaa atttctggtg gtcagcagca
   128101 acgcgttgcc attgcgcgtt cgctgtgtat gaagccgaaa attatgttgt ttgatgagcc
   128161 aacgtcggcg ctcgatccgg agatggtgaa agaggtgctg gatacgatga ttgggctggc
   128221 gcaatcgggt atgacaatgt tgtgtgtaac gcatgagatg gggtttgcgc gaaccgtcgc
   128281 tgaccgggtg atttttatgg atcgtgggga aatagtggag caagctgcac ctgatgaatt
   128341 ttttacgcat cctaaatcag agcgtacgag ggcattttta tcgcaggtaa tccattaatt
   128401 gaatgttagt tcgaaaagca aaaaggccat cctttcggat ggcctttttg cttgatttga
   128461 tgtctggcag tttatggcgg gcgtcctgcc cgccaccctc cgggccgttg cttcgcaacg
   128521 ttcaaatccg ttcccggcgg atttgtcctg gttgggagag tgttcaccga caaacatcaa
   128581 ataaaacaaa aggcccagtc ttccgactga gccttatgtt ttatttgatg tctggcagtt
   128641 ccctactctc gcatggggag accccacact accatcggcg ctacggcgtt tcacttctga
   128701 gttcggcatg gggtcaggtg ggaccaccgc gctactgccg ccagacaaat tcttttctaa
   128761 tctgccgaac tttaacctaa aaagtggtgc tgatacccag agtcgaactg gggacctcac
   128821 ccttaccaag ggtgcgctct accaactgag ccatatcagc acgctaaatt tgatgcctgg
   128881 cagttcccta ctctcgcatg gggagacccc acactaccat cggcgctacg gcgtttcact
   128941 tctgagttcg gcatggggtc aggtgggacc accgcgctaa ggccgccagg caaattctgt
   129001 tttatcagac cgcttctgcg ttctgattta atctgtatca ggctgaaaat cttctctcat
   129061 ccgccaaaac a
//
LOCUS       DAZUDJ010000004       125768 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.004, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000004 DAZUDJ010000000
VERSION     DAZUDJ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 125768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 125768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..125768
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.004"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            7..561
                     /gene="pinE"
                     /locus_tag="ACHY1N_000376"
     CDS             7..561
                     /gene="pinE"
                     /locus_tag="ACHY1N_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA recombinase"
                     /protein_id="HFS4042731.1"
                     /translation="MLIGYVRVSTNDQNTDLQRNALNCAGCELIFEDKISGTKSERPG
                     LKKLLRTLSAGDTLVVWKLDRLGRSMRHLVVLVEELRERGINFRSLTDSIDTSTPMGR
                     FFFHVMGALAEMERELIVERTKAGLEAARAQGRIGGRRPKLTPEQWAQAGRLIASGVP
                     RLKVAIIYDVGISTLYKRFPVGDK"
     gene            complement(642..1289)
                     /locus_tag="ACHY1N_000377"
     CDS             complement(642..1289)
                     /locus_tag="ACHY1N_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4042732.1"
                     /translation="MSEFSNLLNSIPGWLSSSLTALVGTLIGGWFTLKGVTQQAKLSK
                     VETERESLELQLSVLKGVKGEVFTLINLYNKRMKTHIDNIKPGQMLILTFPVGDDNFT
                     FYEQNANVIAKLNDSARDSIINIYTYSRSLIQSFKGNNKLIEDYEKILIGMADNNKDK
                     TMYKRLHDAKINVMVDYAQGIKNIDAELRDAVNKGFNIIDQEVKSLQMKLNKLAS"
     gene            complement(1348..1614)
                     /locus_tag="ACHY1N_000378"
     CDS             complement(1348..1614)
                     /locus_tag="ACHY1N_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001709116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4042733.1"
                     /translation="MRRKESNVSSLPELTNFEVSYSLVTNEVYLSASFTDNMACIPNW
                     PLQEFPDQLICISRAKAVALIEELQKTINYMDAGIDRSSGSLLQ"
     gene            complement(1928..2776)
                     /gene="yfhH"
                     /locus_tag="ACHY1N_000379"
     CDS             complement(1928..2776)
                     /gene="yfhH"
                     /locus_tag="ACHY1N_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4042734.1"
                     /translation="MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEA
                     GVSQSSVVKFAQKLGYKGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKL
                     IKENTAAMYATLNVNSEEKLHECVTMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
                     AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPN
                     ALQQRASHCLYTIAEEQATNSASISACHAQGMLTDLLFIALIQQDLELAPERIRQSEA
                     LMKKLV"
     gene            2985..3620
                     /gene="yfhb"
                     /locus_tag="ACHY1N_000380"
     CDS             2985..3620
                     /gene="yfhb"
                     /locus_tag="ACHY1N_000380"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417055.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HFS4042735.1"
                     /translation="MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIAIALLIKGRAARWPMSLLLWGCTFGHSEARLQTLQADFVRWFRDNVTAFPLVQE
                     RLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQNRWRVTPRGELQQLE"
     gene            3678..4181
                     /gene="tadA"
                     /locus_tag="ACHY1N_000381"
     CDS             3678..4181
                     /gene="tadA"
                     /locus_tag="ACHY1N_000381"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFS4042736.1"
                     /translation="MSEVEFSHEYWMRHALTLAKRAWDEREVPVGAVLVHNNRVIGEG
                     WNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCAGAMIHSRIGRV
                     VFGAHDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFFRMRRQEIKAQK
                     KAQSSTD"
     gene            complement(4178..5734)
                     /gene="mltF"
                     /locus_tag="ACHY1N_000382"
     CDS             complement(4178..5734)
                     /gene="mltF"
                     /locus_tag="ACHY1N_000382"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008933 - lytic transglycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HFS4042737.1"
                     /translation="MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGE
                     LRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNA
                     DLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVV
                     VNDLQTLKETKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELA
                     VALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVD
                     TRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLT
                     KNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHML
                     DARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLF
                     SRKGSEEKQN"
     gene            5992..9879
                     /gene="purL"
                     /locus_tag="ACHY1N_000383"
                     /gene_synonym="purI"
     CDS             5992..9879
                     /gene="purL"
                     /locus_tag="ACHY1N_000383"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HFS4042738.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLN
                     APLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     VNRLERGVAYYIEAGTLTNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTS
                     VDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWVIDGEQQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSEVGRYFADHE
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGD
                     ALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAV
                     TTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPL
                     SLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPAD
                     VRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGINADIASLGD
                     DRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVSGDRFVITANGQT
                     VFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVA
                     APYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLTGRTGLEDFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITSITTESGRVTIMMPHPE
                     RVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG"
     gene            10454..11881
                     /gene="qseE"
                     /locus_tag="ACHY1N_000384"
     CDS             10454..11881
                     /gene="qseE"
                     /locus_tag="ACHY1N_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417051.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HFS4042739.1"
                     /translation="MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     ALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHA
                     GVLPDDKLYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR
                     GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLG
                     NSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETV
                     VSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSS
                     HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     ELYLVDESGQDVCFRIELPSSKNTK"
     gene            12046..12759
                     /gene="qseG"
                     /locus_tag="ACHY1N_000385"
     CDS             12046..12759
                     /gene="qseG"
                     /locus_tag="ACHY1N_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HFS4042740.1"
                     /translation="MRHIFQRLLPRRLWLAGLPCLALLGCVQNHNKPAIDTPAEEKIP
                     VYQLADYLSTECSDIWALQGKSTETNPLYWLRAMDCADRLMPAQSRQQARQYDDGSWQ
                     NTFKQGILLADAKITPYERRQLVARIEALSTEIPAQVRPLYQLWRDGQALQLQLAEER
                     QRYSKLQQSSDSELDTLRQQHHVLQQQLELTTRKLENLTDIERQLSTRKPAGNFSPDT
                     PHESEKPAPSTHEVTPDEP"
     gene            12749..14083
                     /gene="glrR"
                     /locus_tag="ACHY1N_000386"
     CDS             12749..14083
                     /gene="glrR"
                     /locus_tag="ACHY1N_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HFS4042741.1"
                     /translation="MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRV
                     LNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFS
                     FLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSV
                     LINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVS
                     NREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISAT
                     HRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVR
                     AFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFV
                     EARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE"
     gene            14144..14482
                     /gene="glnB"
                     /locus_tag="ACHY1N_000387"
     CDS             14144..14482
                     /gene="glnB"
                     /locus_tag="ACHY1N_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HFS4042742.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(14527..15717)
                     /gene="hmpA"
                     /locus_tag="ACHY1N_000388"
     CDS             complement(14527..15717)
                     /gene="hmpA"
                     /locus_tag="ACHY1N_000388"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008941 - nitric oxide dioxygenase NAD(P)H
                     activity [Evidence IEA];
                     GO_function: GO:0019825 - oxygen binding [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0051409 - response to nitrosative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HFS4042743.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHL
                     LATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAK
                     TPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYR
                     IAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLA
                     MLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLPRFTAHTWYRQPSEADRAK
                     GQFDSEGLMDLSKQEGAFSDPTMQFYLCGPVGFMQFAAKQLVDLGVKQENIHYECFGP
                     HKVL"
     gene            16045..17298
                     /gene="glyA"
                     /locus_tag="ACHY1N_000389"
     CDS             16045..17298
                     /gene="glyA"
                     /locus_tag="ACHY1N_000389"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFS4042744.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEK
                     QAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVAL
                     KEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDS
                     INDEAVIERIKGKVLDICARYPVYA"
     gene            complement(17362..18555)
                     /gene="yphH"
                     /locus_tag="ACHY1N_000390"
     CDS             complement(17362..18555)
                     /gene="yphH"
                     /locus_tag="ACHY1N_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4042745.1"
                     /translation="MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAV
                     SNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACL
                     SPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPGRTINLALAIHGQVDPVTGVSQT
                     MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIG
                     SSFVINEQIYRGSLYGSGQIGHTIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLK
                     SQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSLYNFLNILNINQIWL
                     YGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEA
                     QLRQI"
     gene            18673..21954
                     /gene="yphG"
                     /locus_tag="ACHY1N_000391"
     CDS             18673..21954
                     /gene="yphG"
                     /locus_tag="ACHY1N_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5107 domain-containing protein"
                     /protein_id="HFS4042746.1"
                     /translation="MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYG
                     VTDTLSEQKTLKSWQAVWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPA
                     LVGLLGPWISGGIEFNWPQHHRPTTFMPVDFTLEAHEDGAQTVWVGETEPMHGLQVMT
                     GFTLRPDRAALEIASRVYNGNATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKR
                     AVSAFPIATGTYYKVDYSAGVDISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLH
                     VANHHIAPGKKQWSWGHSEFGQAWDKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEE
                     KRFEQYFLPYHSLGMVQNASRDAVIKLQRSERGIEWGLYAISPLNGYRLAIREIGKCN
                     ALLDDAVALMPATAIQGVLHGINPERLTIELSDADGNIVLSYQEHQPQELPLPDVAKA
                     PLAAQDITSTDEAWFIGQHLEQYHHASRSPFDYYLRGVVLDPLDYRCNLALAMLEYNR
                     ADFPQAVAYATQALKRAHALNKNPQCGQASLIRASAYERQGQYQQAEEDFWRAVWSGN
                     SKAGGYYGLARLAARNGNFDAGLDFCQQSLRACPTNQEVLCLHNLLLVLSGRQDNARL
                     QRAKLLRDYPLNATLWWLNWFDGRSESALAQWRGLCQGRDVNALMTAGQLINWGMPTL
                     AAEMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDVFPQFVRFPNTLEEVAALESI
                     EECWFARHLLACFYYNKRSYNKAITLWQRCVEMSPEFADGWRGLAIHAWNKQHDYELA
                     ARYLDNAYQLAPQDARLLFERDLLDKLSGATPEKRLARLENNLEIALKRDDMTAELLN
                     LWHLTGQADKAADILATRKFHPWEGGEGKVTSQFILNQLLRAWQHLDARQPQQASELL
                     HAALHYPENLSEGRLPGQTDNDIWFWQAICANAQGDETEATRCLRLAATGDRTINIHS
                     YYNDQPVDYLFWQGMALRLLGEQQIAQQLFSEMKQWAQEMAKTSIEADFFAVSQPDLL
                     SLYGDLQQQHKEKCLMVAMLASAGLGEVAQYESARAELTAINPAWPKAALFTTVMPFI
                     FNYVH"
     gene            22051..23034
                     /gene="yphF"
                     /locus_tag="ACHY1N_000392"
     CDS             22051..23034
                     /gene="yphF"
                     /locus_tag="ACHY1N_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFS4042747.1"
                     /translation="MPKKMRTTRNLLLMATLLGSALFARAADKEMTIGAIYLDTQGYY
                     AGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFVDTLVARNVDAIILSAVSENGSS
                     RTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKIY
                     QPKIAVINCEAFEVCVQRRKGFEEVLKSRVPGAQIVANQEGTVLDKAISVGEKLIIST
                     PDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDIS
                     GKKMGNAVFAQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP"
     gene            23057..24568
                     /gene="yphE"
                     /locus_tag="ACHY1N_000393"
     CDS             23057..24568
                     /gene="yphE"
                     /locus_tag="ACHY1N_000393"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HFS4042748.1"
                     /translation="MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLNKGEVRALLGK
                     NGAGKSTLIRMLTGSERPDSGDIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEG
                     LTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEI
                     ARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASC
                     ATVMRDGQVAGDVMLENTSTHHIVSLMLGRDHVDIAPVAPQEIVDQAVLEVRALRHKP
                     KLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLETYEQGEIVINGEKITRPDYGDM
                     LKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMT
                     VKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVREL
                     AAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHSPVNVDELMSAILSVH"
     gene            24593..25591
                     /gene="yphD"
                     /locus_tag="ACHY1N_000394"
     CDS             24593..25591
                     /gene="yphD"
                     /locus_tag="ACHY1N_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4042749.1"
                     /translation="MSASSLSLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNA
                     PGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEV
                     PLAVACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPID
                     ENEVLDWLGGQFLGVPVSALIMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGIN
                     VRRVRILIFTLSGLLAAVTGILLAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRG
                     SLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLANILLTQRSSKAKR"
     gene            25624..26718
                     /gene="yphC"
                     /locus_tag="ACHY1N_000395"
     CDS             25624..26718
                     /gene="yphC"
                     /locus_tag="ACHY1N_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HFS4042750.1"
                     /translation="MKINRIVNEGFMKTMLAAYLPGNSTVDLREVAVPTPGINQVLIK
                     MKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPCGQIVAMGQGCRHFKEGDR
                     VLVYHISGCGFCPNCRRGFPISCTGKGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
                     YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDM
                     LPERLAMAKQLGVMDHGYLATTEGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTA
                     DWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAI
                     THRFSLEQAGDAYALMASGKCGKVVINFPD"
     gene            26730..27602
                     /gene="yphB"
                     /locus_tag="ACHY1N_000396"
     CDS             26730..27602
                     /gene="yphB"
                     /locus_tag="ACHY1N_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HFS4042751.1"
                     /translation="MTIYTLSHGSLKLDVSDQGGVIEGFWRDTTPLLRPGKKSGVATD
                     ASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAHYLHGDGWLGEWQCVSHSDDSLC
                     LVYEHRSGVYHYRVSQAFHLTADTLTVTLSVTNQGAETLPFGTGWHPYFPLSPQTRIQ
                     AQASGYWLEREQWLAGEFCEQLPQELDFNQPAPLPRQWVNNGFAGWNGQARIEQPQEG
                     YAIIMETTPPAPCYFIFVSDPAFDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPG
                     ESTTSEMSLRVALL"
     gene            complement(27650..28072)
                     /gene="yphA"
                     /locus_tag="ACHY1N_000397"
                     /pseudo
     CDS             complement(27650..28072)
                     /gene="yphA"
                     /locus_tag="ACHY1N_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417038.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
     gene            complement(28169..29371)
                     /gene="hcaD"
                     /locus_tag="ACHY1N_000398"
     CDS             complement(28169..29371)
                     /gene="hcaD"
                     /locus_tag="ACHY1N_000398"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylpropionate dioxygenase ferredoxin
                     reductase subunit"
                     /protein_id="HFS4042752.1"
                     /translation="MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYER
                     PPLSKSMLLEDSPQLQQVLPANWWQENNVHLHSGVTIKTLGRDTRELVLTNGESWHWD
                     QLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELA
                     ASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKV
                     ELTLQSGETLQADVVIYGIGISANEQLAREANLDTANGIVIDEACRTCDPAIFAGGDV
                     AITRLDNGALHRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSDQYSDNLQFIGDM
                     RGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQSGKTFDAKLLID
                     ENIALKSL"
     gene            complement(29381..30193)
                     /gene="hcaB"
                     /locus_tag="ACHY1N_000399"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
     CDS             complement(29381..30193)
                     /gene="hcaB"
                     /locus_tag="ACHY1N_000399"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
                     /EC_number="1.3.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate-dihydrodiol/cinnamic
                     acid-dihydrodiol dehydrogenase"
                     /protein_id="HFS4042753.1"
                     /translation="MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVA
                     SLRQRFGEHILAVEGNVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPA
                     ETLETGFHELFNVNVLGYLLGAKACAPALIASEGSMIFTLSNAAWYPGGGGPLYTASK
                     HAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAIL
                     PLQFFPQPADFTGPYVMLASRRNNRALSGVMINADAGLAIRGIRHVAAGLDL"
     gene            complement(30190..30510)
                     /gene="hcaC"
                     /locus_tag="ACHY1N_000400"
     CDS             complement(30190..30510)
                     /gene="hcaC"
                     /locus_tag="ACHY1N_000400"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-phenylpropionate/cinnamic acid
                     dioxygenase ferredoxin subunit"
                     /protein_id="HFS4042754.1"
                     /translation="MNRIYACPVADVPEGEALRIDTSPVIALFNVGGEFYAINDRCSH
                     GNASMSEGYLEDDATVECPLHAASFCLKTGKALCLPATDPLTTYPVHVEGGDIFIDLP
                     EAQP"
     gene            complement(30510..31028)
                     /gene="hcaF"
                     /locus_tag="ACHY1N_000401"
     CDS             complement(30510..31028)
                     /gene="hcaF"
                     /locus_tag="ACHY1N_000401"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008695 - 3-phenylpropionate dioxygenase
                     activity [Evidence IEA];
                     GO_process: GO:0019380 - 3-phenylpropionate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate/cinnamic acid dioxygenase
                     subunit beta"
                     /protein_id="HFS4042755.1"
                     /translation="MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTM
                     RTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNC
                     QISETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQ
                     AVITSHNLSVLF"
     gene            complement(31025..32386)
                     /gene="hcaE"
                     /locus_tag="ACHY1N_000402"
     CDS             complement(31025..32386)
                     /gene="hcaE"
                     /locus_tag="ACHY1N_000402"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008695 - 3-phenylpropionate dioxygenase
                     activity [Evidence IEA];
                     GO_process: GO:0019380 - 3-phenylpropionate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate/cinnamic acid dioxygenase
                     subunit alpha"
                     /protein_id="HFS4042756.1"
                     /translation="MTTPSDLNIYQLIDTQNGRVTPRIYTDPDIYQLELERIFGRCWL
                     FLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLNQCRHRAMRVSYADCGNTRA
                     FTCPYHGWSYGINGELIDVPLEPRAYPQGLCKSHWGLNEVPCVESYKGLIFGNWDTSA
                     PGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNWKFPAEQFASDQYHALFSH
                     ASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGHGSGFFFTEKPDANVWV
                     DGAVSSYYRETYAEAEQRLGEVRALRLAGHNNIFPTLSWLNGTATLRVWHPRGPDQVE
                     VWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENWCEIQKLLKGHRARNSKL
                     CLEMGLGQEKRRDDGIPGITNYIFSETAARGMYQRWADLLSSESWQEVLDKTAAYQQE
                     VMK"
     gene            32522..33412
                     /gene="hcaR"
                     /locus_tag="ACHY1N_000403"
     CDS             32522..33412
                     /gene="hcaR"
                     /locus_tag="ACHY1N_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HcaR"
                     /protein_id="HFS4042757.1"
                     /translation="MELRHLRYFVAVAQALNFTRAAEKLHTSQPSLSSQIRDLENCVG
                     VPLLVRDKRKVALTAAGECFLQDALAILEQAENAKLRARKIVQEDRQLTISFVPSAEV
                     NLLPKVLPMFRLRQPDTLIELVSLITTQQEEKIRRGELDVGLMRHPVYSPEIDYLELF
                     DEPLVVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNI
                     VQVATNILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEM
                     KPALRDFIAIVQERLANVTA"
     gene            33572..34711
                     /gene="hcaT"
                     /locus_tag="ACHY1N_000404"
     CDS             33572..34711
                     /gene="hcaT"
                     /locus_tag="ACHY1N_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HFS4042758.1"
                     /translation="MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLL
                     LGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIG
                     FNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVTMFDYRVIL
                     ALLTLGVASMLLGFLIRPTIQPQGESRQQESTGWSAWLALVRQNWRFLACVCLLQGAH
                     AAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAIC
                     GVVRWGIMGATTALPWLIVVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC"
     gene            complement(34703..35983)
                     /gene="csiE"
                     /locus_tag="ACHY1N_000405"
     CDS             complement(34703..35983)
                     /gene="csiE"
                     /locus_tag="ACHY1N_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HFS4042759.1"
                     /translation="MMPTLAPPSVLSAPQRRCQILLTLFQPGLTATTATFSELNGVDD
                     DIASLDISETGQEILRYHQLTLTAGYDGSYRVEGTVLNQRLCLFHWLRRGFRLCPSFI
                     TSHFTPALKSELKRRGIARNFYDDTNLQALVNLCSRRLQKRFETRDIHFLCLYLQYCL
                     LQHHAGITPQFNPLQRRWAESCLEFQVAQEIGRHWQRRALQPVPPDEPLFMALLFSML
                     RVPDPLRDAHQRDRQLRQSIKRLVNHFRELGNVRFYDEQGLCDQLYTHLAQALNRSLF
                     AIGIDNTLPEEFARLYPRLVRTTRAALAGFESEYGVHLSDEESGLVAVIFGAWLMQEN
                     DLHEKQIILLTGNDSEREAQIEQQLRELTLLPLNIKHMSVKAFLQTGAPRGAALIIAP
                     YTMPLPLFSPPLIYTDLTLTTHQQEQIRKMLESA"
     gene            complement(36174..37028)
                     /gene="yfhR"
                     /locus_tag="ACHY1N_000406"
     CDS             complement(36174..37028)
                     /gene="yfhR"
                     /locus_tag="ACHY1N_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311427.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4042760.1"
                     /translation="MALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGP
                     DPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLP
                     ERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
                     NILAVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIP
                     LLLIHGKADHVIPWQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFI
                     LSALNPQN"
     gene            complement(37173..37976)
                     /gene="suhB"
                     /locus_tag="ACHY1N_000407"
     CDS             complement(37173..37976)
                     /gene="suhB"
                     /locus_tag="ACHY1N_000407"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008934 - inositol monophosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0046854 - phosphatidylinositol phosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HFS4042761.1"
                     /translation="MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVS
                     IAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMLTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            38095..38835
                     /gene="trmJ"
                     /locus_tag="ACHY1N_000408"
     CDS             38095..38835
                     /gene="trmJ"
                     /locus_tag="ACHY1N_000408"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HFS4042762.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGNKAE"
     gene            39105..39593
                     /gene="iscR"
                     /locus_tag="ACHY1N_000409"
     CDS             39105..39593
                     /gene="iscR"
                     /locus_tag="ACHY1N_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HFS4042763.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKL
                     RA"
     gene            39705..40919
                     /gene="iscS"
                     /locus_tag="ACHY1N_000410"
     CDS             39705..40919
                     /gene="iscS"
                     /locus_tag="ACHY1N_000410"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFS4042764.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV
                     QDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNR
                     LWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLE
                     PSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            40947..41333
                     /gene="iscU"
                     /locus_tag="ACHY1N_000411"
     CDS             40947..41333
                     /gene="iscU"
                     /locus_tag="ACHY1N_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HFS4042765.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIAEELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            41350..41673
                     /gene="iscA"
                     /locus_tag="ACHY1N_000412"
     CDS             41350..41673
                     /gene="iscA"
                     /locus_tag="ACHY1N_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HFS4042766.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCG
                     ESFHV"
     gene            41769..42284
                     /gene="hscB"
                     /locus_tag="ACHY1N_000413"
     CDS             41769..42284
                     /gene="hscB"
                     /locus_tag="ACHY1N_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0097428 - protein maturation by iron-sulfur
                     cluster transfer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HFS4042767.1"
                     /translation="MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQ
                     LAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREEL
                     DEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNEAWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            42301..44151
                     /gene="hscA"
                     /locus_tag="ACHY1N_000414"
     CDS             42301..44151
                     /gene="hscA"
                     /locus_tag="ACHY1N_000414"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HFS4042768.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     ADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPH
                     LPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKI
                     ALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVM
                     VGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSE
                     IASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAA
                     AHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV"
     gene            44153..44488
                     /gene="fdx"
                     /locus_tag="ACHY1N_000415"
     CDS             44153..44488
                     /gene="fdx"
                     /locus_tag="ACHY1N_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HFS4042769.1"
                     /translation="MPKIVILPHQDLCPDGAVLEANSGETILDAALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEQEDDMLDKAWGLEPESRLSCQARVTDEDLVVEIPR
                     YTINHAREH"
     gene            44500..44700
                     /gene="iscX"
                     /locus_tag="ACHY1N_000416"
     CDS             44500..44700
                     /gene="iscX"
                     /locus_tag="ACHY1N_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HFS4042770.1"
                     /translation="MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICDLEDFDD
                     DPQASNEKILEAILLVWLDEAE"
     gene            44878..46161
                     /gene="pepB"
                     /locus_tag="ACHY1N_000417"
     CDS             44878..46161
                     /gene="pepB"
                     /locus_tag="ACHY1N_000417"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0019538 - protein metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HFS4042771.1"
                     /translation="MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLI
                     QRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVEWPDLDDAQRQELDN
                     RLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGL
                     HTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNT
                     DAEGRLVLADGLIDASAQKPELIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLAS
                     ASQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGW
                     LHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA"
     gene            46303..47079
                     /gene="sseB"
                     /locus_tag="ACHY1N_000418"
     CDS             46303..47079
                     /gene="sseB"
                     /locus_tag="ACHY1N_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708361.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HFS4042772.1"
                     /translation="MSETKNELEDLLEKAATEPAHRPAFFRTLLESTVWVPGTAAQGE
                     AVVEDSALDLQHWEKEDGTSVIPFFTSLEALQQAVEDEQAFVVMPVRTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLIGGEGNPLSSQEILEGGESLILSEVAEPPAQMIDSLTT
                     LFKTIKPVKRAFICSIKENEEAQPNLLIGIEADGDIEEIIQATGSVATDTLPGDEPID
                     ICQVKKGEKGISHFITEHIAPFYERRWGGFLRDFKQNRII"
     gene            complement(47111..47236)
                     /gene="timP"
                     /locus_tag="ACHY1N_000419"
     CDS             complement(47111..47236)
                     /gene="timP"
                     /locus_tag="ACHY1N_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010283914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small toxic inner membrane protein TimP"
                     /protein_id="HFS4042773.1"
                     /translation="MKIRCFCIVLIVSGALFSQVNNNRSLSGDNLLVVNNLQSSK"
     gene            complement(47898..48743)
                     /gene="sseA"
                     /locus_tag="ACHY1N_000420"
     CDS             complement(47898..48743)
                     /gene="sseA"
                     /locus_tag="ACHY1N_000420"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004792 - thiosulfate sulfurtransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HFS4042774.1"
                     /translation="MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLN
                     GHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAP
                     RAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDV
                     LLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDE
                     LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLP
                     VEPVK"
     gene            48950..53911
                     /gene="yfhM"
                     /locus_tag="ACHY1N_000421"
     CDS             48950..53911
                     /gene="yfhM"
                     /locus_tag="ACHY1N_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha2-macroglobulin"
                     /protein_id="HFS4042775.1"
                     /translation="MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSEN
                     ASSAKLSVPERQKLAQQSAGKVLTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIH
                     VVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDYEKTIT
                     TRDIQPSVGFASRGSLLPGKVVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRN
                     SLANWQSDKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAG
                     RYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQA
                     TSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFG
                     PRDLYRPGETVILNGLLRDADGKALPNQPIKLDVIKPDGQVLRSVVSQPENGLYHFTW
                     PLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSV
                     VGYYLYGAPANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDK
                     GRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASK
                     SVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSE
                     DEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAG
                     YSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWW
                     QEIDVPAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDEN
                     RRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITDYVTPDP
                     WQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVAQQA
                     LPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRF
                     MASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSDSPAAVELAPGVRTTLFIPVR
                     ALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAI
                     PADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAA
                     QLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLV
                     RAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQ
                     KAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIVLALKTPRNSDERIW
                     LGDYGSPLRDNALMLYLLEENKLLPDEQNTLLNTLSQQAFGERWLSTQESNALFLAAR
                     TIQDLPGKWQAQTSFSAEPLTGEKTLNSNLNSDQLATLQVRNSGDQPLWLRVDASGYP
                     QSAPLPANNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLP
                     AGLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPV
                     TLVYLARAVTPGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP"
     gene            53912..56224
                     /gene="pbpC"
                     /locus_tag="ACHY1N_000422"
     CDS             53912..56224
                     /gene="pbpC"
                     /locus_tag="ACHY1N_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417014.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HFS4042776.1"
                     /translation="MPRLLTKRGCWITLAAAPFLLFLAAWGADKLWPLPLHEVNPARV
                     VVAQDGTPLWRFADADGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARA
                     AWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLY
                     LNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSRLRPDRWPERAEAA
                     RNKVLERMAVQGVWSREQVKESREEPIWLAPRQMPQLAPLFSRMMLGKSKSDKIVTTL
                     DAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRFGHVDMV
                     NAIRSPGSVLKPFVYGLALDEGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILGGAGAKLEDMAA
                     AYTAFARHGKAGKLRLQPDDPLLERPLMSSGAAWIIRRIMADEAKPLPDSALPRVAPL
                     AWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNILLS
                     RSANLPEDPRPNSVTRGVICWPGGQSLPEGDGNCRRRLATWLLDGSQPPTLLLPDQEG
                     INGIRFPIWLDENGKRVAADCPQARQEMINVWPLPLEPWLPASERRAVRLPPASTICP
                     SYGHDAQLPLQLTGVRDGAIIKRLPGAAEATLPLQSSGGAGERWWFLNGEPLTERGRN
                     VTLHLTDKGDYQLLVMDDVGQIATVKFVMQ"
     gene            56373..56804
                     /gene="ndk"
                     /locus_tag="ACHY1N_000423"
     CDS             56373..56804
                     /gene="ndk"
                     /locus_tag="ACHY1N_000423"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFS4042777.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR"
     gene            56954..58108
                     /gene="rlmN"
                     /locus_tag="ACHY1N_000424"
     CDS             56954..58108
                     /gene="rlmN"
                     /locus_tag="ACHY1N_000424"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HFS4042778.1"
                     /translation="MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQ
                     VMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQ
                     RVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVG
                     AAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPA
                     LDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVT
                     IEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVL
                     MSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV"
     gene            58393..59406
                     /gene="rodZ"
                     /locus_tag="ACHY1N_000425"
     CDS             58393..59406
                     /gene="rodZ"
                     /locus_tag="ACHY1N_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HFS4042779.1"
                     /translation="MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELSSNSEQ
                     GQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPAVTAPAPAVDPQQNAVVSPSQANV
                     DTAATPAPTATTTPDGAAPLPTDQAGVTTPAADPNALVMNFTADCWLEVTDATGKKLF
                     SGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQS
                     PAQ"
     gene            59433..60551
                     /gene="ispG"
                     /locus_tag="ACHY1N_000426"
                     /gene_synonym="gcpE"
     CDS             59433..60551
                     /gene="ispG"
                     /locus_tag="ACHY1N_000426"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HFS4042780.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK"
     gene            60662..61936
                     /gene="hisS"
                     /locus_tag="ACHY1N_000427"
     CDS             60662..61936
                     /gene="hisS"
                     /locus_tag="ACHY1N_000427"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFS4042781.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQAL
                     LNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLV
                     ASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEV
                     ANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            61954..62574
                     /gene="yfgM"
                     /locus_tag="ACHY1N_000428"
     CDS             61954..62574
                     /gene="yfgM"
                     /locus_tag="ACHY1N_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ancillary SecYEG translocon subunit YfgM"
                     /protein_id="HFS4042782.1"
                     /translation="MEIYENENDQVEAVKRFFAENGKALAVGVILGVGALIGWRYWNS
                     HQVDSARSASLAYQNAVTAVSEGKPDSIPAAEKFAAENKNTYGALASLELAQQFVDKN
                     ELEKAAAQLQQGLADTSDENLKAVINLRLARVQVQLKQADAALKTLDTIKGEGWAAIV
                     ADLRGEALLSKGDKQGARSAWEAGVKSDVTPALSEMMQMKINNLSI"
     gene            62585..63763
                     /gene="bamB"
                     /locus_tag="ACHY1N_000429"
     CDS             62585..63763
                     /gene="bamB"
                     /locus_tag="ACHY1N_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HFS4042783.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTP
                     TTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDG
                     WFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG
                     LVLIHTSNGQLQALNEPDGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSA
                     VLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWAQSDLLHRLLTSPVLYN
                     GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
                     "
     gene            63881..65353
                     /gene="der"
                     /locus_tag="ACHY1N_000430"
     CDS             63881..65353
                     /gene="der"
                     /locus_tag="ACHY1N_000430"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417006.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFS4042784.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMG
                     SPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK"
     gene            65422..65637
                     /gene="yfgJ"
                     /locus_tag="ACHY1N_000431"
     CDS             65422..65637
                     /gene="yfgJ"
                     /locus_tag="ACHY1N_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417005.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFS4042785.1"
                     /translation="MELHCPQCQHVLDQDNGHARCPSCGEIIEMKALCPDCHQPLQVL
                     KACGAVDYFCQHGHGLISKKRVEFVLA"
     gene            complement(65634..67004)
                     /gene="xseA"
                     /locus_tag="ACHY1N_000432"
     CDS             complement(65634..67004)
                     /gene="xseA"
                     /locus_tag="ACHY1N_000432"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFS4042786.1"
                     /translation="MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESM
                     QPAGEGLLQQKYEQLKAKLQAEGLFDLQYKKPLPSPAHCVGVITSKTGAALHDILHVL
                     KRRDPSLPVIIYPTAVQGDDAPGQTVRAIELANQRNECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQS
                     TRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQL
                     KRTGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRVQLSATRERFGNAVTH
                     LEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKK
                     SRKKVH"
     gene            67166..68632
                     /gene="guaB"
                     /locus_tag="ACHY1N_000433"
     CDS             67166..68632
                     /gene="guaB"
                     /locus_tag="ACHY1N_000433"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFS4042787.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            68701..70278
                     /gene="guaA"
                     /locus_tag="ACHY1N_000434"
     CDS             68701..70278
                     /gene="guaA"
                     /locus_tag="ACHY1N_000434"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFS4042788.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEA
                     SNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            complement(70373..70912)
                     /gene="yfgI"
                     /locus_tag="ACHY1N_000435"
     CDS             complement(70373..70912)
                     /gene="yfgI"
                     /locus_tag="ACHY1N_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5384 family protein"
                     /protein_id="HFS4042789.1"
                     /translation="MKKVFLCAILASLSYPAIASSLQDQLSAVAEAEQQGKNEEQKQH
                     DEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEASADKKRDQSYE
                     DELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANRNMTEGGR
                     DLMKSVGKAEENKSDSWFN"
     gene            complement(70928..71446)
                     /gene="yfgH"
                     /locus_tag="ACHY1N_000436"
     CDS             complement(70928..71446)
                     /gene="yfgH"
                     /locus_tag="ACHY1N_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HFS4042790.1"
                     /translation="MMKFKKCLLPVAMLASFTLAGCQSNADDHAADVYQTDQLNTKQE
                     TKTVNIISILPAKVAVDNSQNKRNAQAFGALIGAVAGGVIGHNVGSGSNSGTTAGAVG
                     GGAVGAAAGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNET
                     RIQPNTKCPEKS"
     gene            complement(71757..71948)
                     /gene="yfgG"
                     /locus_tag="ACHY1N_000437"
     CDS             complement(71757..71948)
                     /gene="yfgG"
                     /locus_tag="ACHY1N_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfgG family protein"
                     /protein_id="HFS4042791.1"
                     /translation="MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHH
                     QSKKEAQQSTLSVESPVQR"
     gene            71966..72118
                     /locus_tag="ACHY1N_000438"
     CDS             71966..72118
                     /locus_tag="ACHY1N_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4042792.1"
                     /translation="MSHAVDGTYIKAQQDKMVNSSLCKKASVDTYFNVMEVNLIIYND
                     DVIMMN"
     gene            72300..74543
                     /gene="pdeF"
                     /locus_tag="ACHY1N_000439"
     CDS             72300..74543
                     /gene="pdeF"
                     /locus_tag="ACHY1N_000439"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeF"
                     /protein_id="HFS4042793.1"
                     /translation="MKLNATYIKIRDKWWGLPLFLPSLILPIFAHINTFAHISSGEVF
                     LFYLPLALMISMMMFFSWAALPGITLGIFVRKYAELGFYETLSLTANFIIIIILCWGG
                     YRVFTPRRNNVSHGDTRLISQRIFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMP
                     FNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDAKVTKKEFAL
                     WLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMI
                     SIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQRAVVRRIQRLAYVDP
                     VVHLPNVRALNRALRDAPWSALCYLRIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLE
                     PGEDVYQLSGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRS
                     PVNHIYLLLGELNTVAELSIVTNAPENMQRRGAMYLQRELKDKVAMMNRLQQALEHNH
                     FFLMAQPITGMRGDVYHEILLRMKGENDELIGPDSFLPVAHEFGLSSSIDMWVIEHTL
                     QFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLAKYQIEAWQLIFEVTESNALT
                     NVKQAQITLQHLQELGCQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKKMRVVAEYVENEEIREAVLSLGIDYMQGYLIGKPQPLIDTLNEI
                     EPIRESA"
     gene            complement(74582..76123)
                     /gene="ppx"
                     /locus_tag="ACHY1N_000440"
     CDS             complement(74582..76123)
                     /gene="ppx"
                     /locus_tag="ACHY1N_000440"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004309 - exopolyphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006798 - polyphosphate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HFS4042794.1"
                     /translation="MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPI
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASG
                     TIKAAHEVLMEMGEKDGIITPERLEKLVKEVLRHRNFASLSLPGLSEERKTVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQAR
                     RVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNS
                     DLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEEST
                     PEIAA"
     gene            complement(76128..78194)
                     /gene="ppk1"
                     /locus_tag="ACHY1N_000441"
     CDS             complement(76128..78194)
                     /gene="ppk1"
                     /locus_tag="ACHY1N_000441"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009358 - polyphosphate kinase complex
                     [Evidence IEA];
                     GO_function: GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006799 - polyphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HFS4042795.1"
                     /translation="MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVE
                     IIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGM
                     CSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEV
                     ATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIK
                     SLEQPE"
     gene            complement(78365..79003)
                     /gene="purN"
                     /locus_tag="ACHY1N_000442"
     CDS             complement(78365..79003)
                     /gene="purN"
                     /locus_tag="ACHY1N_000442"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFS4042796.1"
                     /translation="MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLE
                     RARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD
                     TEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE"
     gene            complement(79003..80040)
                     /gene="purM"
                     /locus_tag="ACHY1N_000443"
     CDS             complement(79003..80040)
                     /gene="purM"
                     /locus_tag="ACHY1N_000443"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFS4042797.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPL
                     ADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQW
                     PEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNSNGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            80365..80991
                     /gene="upp"
                     /locus_tag="ACHY1N_000444"
     CDS             80365..80991
                     /gene="upp"
                     /locus_tag="ACHY1N_000444"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFS4042798.1"
                     /translation="MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK"
     gene            81077..82366
                     /gene="uraA"
                     /locus_tag="ACHY1N_000445"
     CDS             81077..82366
                     /gene="uraA"
                     /locus_tag="ACHY1N_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HFS4042799.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTII
                     ISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTL
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVI
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGM
                     ALATIVGIGLSLIFKLISVLRPEEVVLDAEDADITDK"
     gene            82461..83162
                     /gene="hda"
                     /locus_tag="ACHY1N_000446"
     CDS             82461..83162
                     /gene="hda"
                     /locus_tag="ACHY1N_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416991.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HFS4042800.1"
                     /translation="MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSG
                     YIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCID
                     NIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIY
                     KLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITA
                     QRKLTIPFVKEILKL"
     gene            complement(83300..83659)
                     /gene="arsC"
                     /locus_tag="ACHY1N_000447"
     CDS             complement(83300..83659)
                     /gene="arsC"
                     /locus_tag="ACHY1N_000447"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311384.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HFS4042801.1"
                     /translation="MTKQVKIYHNPRCSKSRETLNLLKENGVEPEVVLYLETPADAAT
                     LRDLLKMLGMNSARELMRQKEDLYKELNLADSSLSEEALIQAMVDNPKLMERPIVVAN
                     GKARIGRPPEQVLEIVG"
     gene            complement(83680..85143)
                     /gene="bepA"
                     /locus_tag="ACHY1N_000448"
     CDS             complement(83680..85143)
                     /gene="bepA"
                     /locus_tag="ACHY1N_000448"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HFS4042802.1"
                     /translation="MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTL
                     SIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFD
                     PQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYL
                     AKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQP
                     LLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQP
                     QEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLL
                     SSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM"
     gene            85356..86417
                     /gene="yfgO"
                     /locus_tag="ACHY1N_000449"
     CDS             85356..86417
                     /gene="yfgO"
                     /locus_tag="ACHY1N_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4042803.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLV
                     AIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLL
                     TIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVL
                     EMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGAGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVIHAWPDGQIAQE"
     gene            complement(86455..87306)
                     /gene="focB"
                     /locus_tag="ACHY1N_000450"
     CDS             complement(86455..87306)
                     /gene="focB"
                     /locus_tag="ACHY1N_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocB"
                     /protein_id="HFS4042804.1"
                     /translation="MHEKQTLFDLQLSARKAAIAERIAAHKIARSKVSVFLMAMSAGV
                     FMAIGFTFYLSVIADTPSSQALTHLVGGLCFTLGFILLAVCGTNLFTSSVMTVMAKSR
                     GVISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHT
                     FTESVSLGIMCNLMVCLALWMSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIP
                     FAIAIRHFAPTSFWQLAHSSADNFPALTVSHFITANLLPVMLGNIIGGAVLVSMCYRA
                     IYLRQES"
     gene            complement(87324..89336)
                     /gene="hyfR"
                     /locus_tag="ACHY1N_000451"
     CDS             complement(87324..89336)
                     /gene="hyfR"
                     /locus_tag="ACHY1N_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HyfR"
                     /protein_id="HFS4042805.1"
                     /translation="MAMSDEAMFAPPQGITIEAVNGMLAERLAQKHGKASLLRAFIPM
                     PPPFSPVQLIELHVLKSNFYYRYHDDGSDVTATTEYQGEMVDYSRHAVLLGSSGMAEL
                     RFIRTHGSRFTPQDCTLFNWLARIITPVLQSWLNDEEQQVALRLLEKDRDHHRVLVDI
                     TNAVLSHFDLDDLIADVAREIHHFFGLASVSMVLGDHRKNEKFSLWCSDLSASHCACL
                     PRSMPGDSVLLTQTLQTRQPTLTHRADDLFLWQRDPLLLLLASNGCESALLIPLTFGN
                     HTPGALLLAHTSSTLFSEENCQLLQHIADRIAIAVGNADAWRSMTDLQESLQQENHQL
                     SEQLLSNLGIGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLS
                     PRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGD
                     LPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRL
                     NVFPLELPPLRDRPEDIPLLAKHFTQKMARHMNRSIDAIPTEALRQLMSWDWPGNVRE
                     LENVIERAVLLTRGNSLNLHLNVRQSRLLPTLNEDSALRSSMAQLLHPTTPENDEEER
                     QRIVQVLRETNGIVAGPRGAATRLGMKRTTLLSRMQRLGISVREVL"
     gene            complement(89366..89779)
                     /gene="hyfJ"
                     /locus_tag="ACHY1N_000452"
     CDS             complement(89366..89779)
                     /gene="hyfJ"
                     /locus_tag="ACHY1N_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416985.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 assembly chaperone HyfJ"
                     /protein_id="HFS4042806.1"
                     /translation="MAEECGEIVFWTLRKKFVASSDEMPEHSSQVMYYSLAIGHHVGV
                     IDCLNVAFRCPLTEYEDWLALVEEEQARRKMLGVMTFGEIVIDASHTALLTRAFAPLA
                     DDATSVWQARSIQFIHLLDEIVQEPAIYLMARKIA"
     gene            complement(89772..90529)
                     /gene="hyfI"
                     /locus_tag="ACHY1N_000453"
                     /pseudo
     CDS             complement(89772..90529)
                     /gene="hyfI"
                     /locus_tag="ACHY1N_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075566.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfI"
     gene            complement(90526..91064)
                     /gene="hyfH"
                     /locus_tag="ACHY1N_000454"
                     /pseudo
     CDS             complement(90526..91064)
                     /gene="hyfH"
                     /locus_tag="ACHY1N_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311377.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit H"
     gene            complement(91074..92741)
                     /gene="hyfG"
                     /locus_tag="ACHY1N_000455"
     CDS             complement(91074..92741)
                     /gene="hyfG"
                     /locus_tag="ACHY1N_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfG"
                     /protein_id="HFS4042807.1"
                     /translation="MNVNSSSNRGEAILAALKTQFPGAVLDEERQTPEQVTITVKINL
                     LPDVVHYLYYQHDGWLPVLFGNDERTLNGHYAVYYALSMEGAEKCWIVVKALVDADSR
                     EFPSVTPRVPAAVWGEREIRDMYGLIPVGLPDQRRLVLPDDWPEDMHPLRKDAMDYRL
                     RPEPTTDSETYPFINEGNSDAQVIPVGPLHITSDELGHFRLFVDGEQIVDADYRLFYV
                     HRGMEKLAETRMGYNEVTFLSDRVCGICGFAHSVAYTNSVENALGIEVPQRAHTIRSI
                     LLEVERLHSHLLNLGLSCHFVGFDTGFMQFFRVREKSMTMAELLIGSRKTYGLNLIGG
                     VRRDILKEQRLQTLKLVREMRADVSELVEMLLATPNMEQRTQGIGILDRQIARDLRFD
                     HPYADYGNIPKTLFTFTGGDVFSRVMVRVKETFDSLAMLEFALDNMPDTPLLTEGFSY
                     KPHAFALGFVEAPRGEDVHWSMLGDNQKLFRWRCRAATYANWPVLRYMLRGNTVSDAP
                     LIIGSLDPCYSCTDRVTLVDVRKRQSKTVPYKEIERYGIDRNRSPLK"
     gene            complement(92731..94317)
                     /gene="hyfF"
                     /locus_tag="ACHY1N_000456"
     CDS             complement(92731..94317)
                     /gene="hyfF"
                     /locus_tag="ACHY1N_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit F"
                     /protein_id="HFS4042808.1"
                     /translation="MSYSVMFALLLLTPLLFSLLCFACRKRGLSATCTVTVLHSLGIT
                     LLLILALWVVQTAADAGEIFAAGLWLHIDGLGGLFLAILGVIGFLTGVYSIGYMRHEV
                     AHGELSPVTLCDYYGFFHLFLFTMLLVVTSNNLIVMWAAIEATTLSSAFLVGIYGQRS
                     SLEAAWKYIIICTVGVAFGLFGTVLVYANVASVMPQAEMAIFWSEVLKQSSLLDPTLM
                     LLAFVFVLIGFGTKTGLFPMHAWLPDAHSEAPSPVSALLSAVLLNCALLVLIRYYIII
                     CQAIGSDFPNRLLLIFGMLSVAVAAFFILVQRDIKRLLAYSSVENMGLVAVALGIGGP
                     LGIFAALLHTLNHSLAKTLLFCGSGNVLLKYGTRDLNVVCGMLKIMPFTAVLFGGGAL
                     ALALAGMPPFNIFLSEFMTITAGLARNHLLIIVLLLLLLTLVLAGLVRMAARVLMAKP
                     PQAVNRGDLGWLTTSPMVILLVMMLAMGTHIPQPVIRILAGASTIVLSGTHDLPAQRS
                     TWHDFLPSGTASVSEKHSER"
     gene            complement(94322..94972)
                     /gene="hyfE"
                     /locus_tag="ACHY1N_000457"
     CDS             complement(94322..94972)
                     /gene="hyfE"
                     /locus_tag="ACHY1N_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 membrane subunit"
                     /protein_id="HFS4042809.1"
                     /translation="MTGSMIVNNLAGLMMLTSLFVISVKSYRLSCGFYACQSLVLVSI
                     FATLSCLFAAEQLLIWSASAFITKVLLVPLIMTYAARNIPQNIPEKALFGPAMMALLA
                     ALIVLLCAFVVQPVKLPMATGLKPALAVALGHFLLGLLCIVSQRNILRQIFGYCLMEN
                     GSHLVLALLAWRAPELVEIGIATDAIFAVIVMVLLARKIWRTHGTLDVNNLTALKG"
     gene            complement(94984..96214)
                     /locus_tag="ACHY1N_000458"
                     /pseudo
     CDS             complement(94984..96214)
                     /locus_tag="ACHY1N_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit D"
     gene            complement(96231..97178)
                     /gene="hyfC"
                     /locus_tag="ACHY1N_000459"
     CDS             complement(96231..97178)
                     /gene="hyfC"
                     /locus_tag="ACHY1N_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311372.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfC"
                     /protein_id="HFS4042810.1"
                     /translation="MRQTLYDGYLVIFALAQAVILLMLTPLFTGISRQIRARMHSRRG
                     PGIWQDYRDIHKLFKRQEVAPISSGLMFRLMPWVLISSMLVLAMALPLFITVSPFAGG
                     GDLITLIYLLALFRFFFALSGLDTGSPFAGVGASRELTLGILVEPMLILSLLVLALIA
                     GSTHIEMISNTLATGWNSPLTTVLALLACGFACFIEMGKIPFDVAEAEQELQEGPLTE
                     YSGAGLALAKWGLGLKQVVMAALFVALFLPFGRAQELSLACLLTSLVVTLLKVLLIFV
                     LASIAENTLARGRFLLIHHVTWLGFSLAALAWVFWLTGL"
     gene            complement(97189..99207)
                     /gene="hyfB"
                     /locus_tag="ACHY1N_000460"
     CDS             complement(97189..99207)
                     /gene="hyfB"
                     /locus_tag="ACHY1N_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit B"
                     /protein_id="HFS4042811.1"
                     /translation="MDALQLLTWSLILYLFASLASLFLLGLDRLAIKLSGITSLVGGV
                     IGIISGITQLHAGVTLVARFATPFDFADFTLRMDSLSAFMVLVISLLVVVCSLYSLTY
                     MREYEGKGAAAMGFFMNLFIASMVALLVMDNAFWFIVLFEMMSLSSWFLVIARQDKTS
                     INAGMLYFFIAHAGSVLIMIAFLLMGRESGSLDFASFRTLSLSPGLASAVFLLAFFGF
                     GAKAGMMPLHSWLPRAHPAAPSHASALMSGVMVKIGIFGILKVAMDLLAQTGLPLWWG
                     ILVMAIGAISALLGVLYALAEQDIKRLLAWSTVENVGIILLAVGVAMVGLSLHDPLLT
                     VVGLLGALFHLLNHALFKGLLFLGAGAIISRLHTHDMEKMGALAKRMPWTAAACLIGC
                     LAISAIPPLNGFISEWYTWQSLFSLSRVEAVALQLAGPIAMVMLAVTGGLAVMCFVKM
                     YGITFCGAPRSTHAEEAQEVPNTMIVAMLLLAALCVLIALSASWLAPKIMHIAHAFTN
                     TPPVTVASGIALVPGTFHTQVTPSLLLLLLLAMPLLPGLYWLWCRSRRAAFRRTGDAW
                     ACGYGWENAMAPSGNGVMQSLRVVFSALFRLRQQFDPTLRLNKGLAHVTARAQSTEPF
                     WDERVIRPIVSATQRLAKEIQHLQSGDFRLYCLYVVAALVVLLIAIAV"
     gene            complement(99207..99824)
                     /gene="hyfA"
                     /locus_tag="ACHY1N_000461"
     CDS             complement(99207..99824)
                     /gene="hyfA"
                     /locus_tag="ACHY1N_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311370.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfA"
                     /protein_id="HFS4042812.1"
                     /translation="MNRFVVAEPLWCTGCNTCLAACSDVHKTQGLQQHPRLALAKTST
                     LTAPVVCHHCEEAPCLQVCPVNAISQRDDAIQLNESLCIGCKLCAVVCPFGAISASGS
                     RPVNAPAQYVFQAEGSLKDGEENVPPQHALLRWEPGVQTVAVKCDLCDFLPEGPACVR
                     ACPNQALRLITDDSLQRQMKEKQRLAASWFANGGEDPLSLTQEQR"
     gene            complement(100077..100547)
                     /gene="bcp"
                     /locus_tag="ACHY1N_000462"
     CDS             complement(100077..100547)
                     /gene="bcp"
                     /locus_tag="ACHY1N_000462"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HFS4042813.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA"
     gene            complement(100547..101119)
                     /gene="gcvR"
                     /locus_tag="ACHY1N_000463"
     CDS             complement(100547..101119)
                     /gene="gcvR"
                     /locus_tag="ACHY1N_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HFS4042814.1"
                     /translation="MTLSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GEEFTFIMLLSGSWNAITLIESTLPLKGAELDLLIVMKRTTARPRPPMPASVWVQVDV
                     ADSPHLIERFTALFDAHHMNIAELVSRTQPAENERAAQLHIQITAHSPASADAANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            101265..102143
                     /gene="dapA"
                     /locus_tag="ACHY1N_000464"
     CDS             101265..102143
                     /gene="dapA"
                     /locus_tag="ACHY1N_000464"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFS4042815.1"
                     /translation="MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGT
                     TGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
                     KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMC
                     KLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITD
                     SGRETVRAALKHAGLL"
     gene            102160..103194
                     /gene="bamC"
                     /locus_tag="ACHY1N_000465"
     CDS             102160..103194
                     /gene="bamC"
                     /locus_tag="ACHY1N_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HFS4042816.1"
                     /translation="MAYSVQKSRLAKIAGVSLVLLLAACSSDSRYKRQVSGDEAYLEA
                     APLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGD
                     TASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAAN
                     AAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNM
                     AVTYKPLSDSDWQELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFSK"
     gene            103407..104120
                     /gene="purC"
                     /locus_tag="ACHY1N_000466"
     CDS             103407..104120
                     /gene="purC"
                     /locus_tag="ACHY1N_000466"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFS4042817.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLV
                     KRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSL
                     GGLIEAYEAVARRLGVQLD"
     gene            104275..104502
                     /gene="vapB"
                     /locus_tag="ACHY1N_000467"
     CDS             104275..104502
                     /gene="vapB"
                     /locus_tag="ACHY1N_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system antitoxin VapB"
                     /protein_id="HFS4042818.1"
                     /translation="METTVFLSNRSQAVRLPKAVALPEDVKKVEIIAIGRTRIITPAG
                     ESWDSWFDGENVSADFMDIRDQPAMQERESF"
     gene            104502..104900
                     /locus_tag="ACHY1N_000468"
     CDS             104502..104900
                     /locus_tag="ACHY1N_000468"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HFS4042819.1"
                     /translation="MLKFMLDTNICIFTIKNKPVHVRERFNLNSGRMCISSVTLMELI
                     YGAEKSQMPERNLAVIEGFVSRLVVLDYDSAAATHTGQIRAELARQGRPVGPFDQMIA
                     GHARSRGLIVVTNNTREFERVAGIRLEDWS"
     gene            105047..105910
                     /gene="ypfJ"
                     /locus_tag="ACHY1N_000469"
     CDS             105047..105910
                     /gene="ypfJ"
                     /locus_tag="ACHY1N_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HFS4042820.1"
                     /translation="MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLLVV
                     LVAGYYGVDLTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMG
                     KTYQQPKLVMYRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFA
                     QGYVIAHEVGHHVQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWGHSMQ
                     QQGVLETGDLEEALNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGD
                     PAQCNTFGKSI"
     gene            105925..107940
                     /gene="tmcA"
                     /locus_tag="ACHY1N_000470"
     CDS             105925..107940
                     /gene="tmcA"
                     /locus_tag="ACHY1N_000470"
                     /EC_number="2.3.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cytosine(34) acetyltransferase TmcA"
                     /protein_id="HFS4042821.1"
                     /translation="MAELTALHTLTAQMKREGIRRLLVLSGEEGWCFDHALKLRDALP
                     GDWLWISPQPDAENHCSPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWL
                     VLLLPVWEEWENQPDADSLRWSDCPDPIATPHFVQHLKRVLTADNDAILWRQNQPFSL
                     AHFTPRTDWHPATGAPQPEQQQLLQQLLTMPPGVAAVTAARGRGKSALAGQLISRIAG
                     SAIVTAPAKAATDVLAQFAGEKFRFIAPDALLASDEQADWLVVDEAAAIPAPLLHQLV
                     SRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEAL
                     VFDDENFTHTPQGNIVISAFEQTLWRSEPETPLKVYQLLSGAHYRTSPLDLRRMMDAP
                     GQHFLQAAGENEIAGALWLVDEGGLSQQLSQAVWAGFRRPRGNLVAQSLAAHGSNPLA
                     ATLRGRRVSRIAVHPARQREGTGQQLIAGALQYTRDLDYLSVSFGYTGELWRFWHRCG
                     FVLVRMGNHREASSGCYTAMALLPMSNAGKQLAEREHYRLRRDAQALAKWNGETLPVD
                     PLNDAVLSDDDWLELAGFAFAHRPLLTSLGCLLRLLQTSELALPALRGRLQKNVSDAQ
                     LCTTLKLSGRKMLLVRQREEAAQALFALNDVRTERLRDRITQWQFFH"
     gene            108014..108712
                     /gene="ypfH"
                     /locus_tag="ACHY1N_000471"
     CDS             108014..108712
                     /gene="ypfH"
                     /locus_tag="ACHY1N_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311362.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFS4042822.1"
                     /translation="MKHDHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIGSWFAPLFP
                     DALVVSVGGAEPSGNPAGRQWFSVQGITEDNRQARVDAIMPTFIETVRYWQKQSGVGA
                     NATALIGFSQGAIMALESIKAEPGLASRVIAFNGRYASLPETASTATTIHLIHGGEDP
                     VIDLAHAVAAQEALISAGGDVTLDIVEDLGHAIDNRSMQFALDHLRYTIPKHYFDEAL
                     SGGKPGDDDVIEMM"
     gene            complement(108822..109022)
                     /gene="ypfN"
                     /locus_tag="ACHY1N_000472"
     CDS             complement(108822..109022)
                     /gene="ypfN"
                     /locus_tag="ACHY1N_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HFS4042823.1"
                     /translation="MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPP
                     HRDFNDKWDDDDDWPKKDQPKK"
     gene            complement(109050..110177)
                     /gene="dapE"
                     /locus_tag="ACHY1N_000473"
     CDS             complement(109050..110177)
                     /gene="dapE"
                     /locus_tag="ACHY1N_000473"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009014 - succinyl-diaminopimelate
                     desuccinylase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HFS4042824.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMD
                     FADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLV
                     GEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIE
                     WDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            complement(110181..110537)
                     /gene="yffB"
                     /locus_tag="ACHY1N_000474"
     CDS             complement(110181..110537)
                     /gene="yffB"
                     /locus_tag="ACHY1N_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HFS4042825.1"
                     /translation="MVTLYGIKNCDTIKKARRWLEANNIDYRFHDYRVDGLDSELLNG
                     FINELGWEALLNTRGTTWRKLDETTRNKITDAASAAALMTEMPAIIKRPLLCAPGKPM
                     LLGFSDSSYQQFFHEV"
     gene            110918..110977
                     /gene="ypfM"
                     /locus_tag="ACHY1N_000475"
     CDS             110918..110977
                     /gene="ypfM"
                     /locus_tag="ACHY1N_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YpfM"
                     /protein_id="HFS4042826.1"
                     /translation="MIERELGNWKDFIEVMLRK"
     gene            complement(111076..114189)
                     /gene="acrD"
                     /locus_tag="ACHY1N_000476"
     CDS             complement(111076..114189)
                     /gene="acrD"
                     /locus_tag="ACHY1N_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HFS4042827.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVR
                     VTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYD
                     YLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPHGLEYKVAYETTSFVK
                     ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQ
                     KGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFLPLE
                     DRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVA
                     RMFIRLKDWSERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVA
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF
                     PLKPRPE"
     gene            complement(114353..116053)
                     /gene="narQ"
                     /locus_tag="ACHY1N_000477"
     CDS             complement(114353..116053)
                     /gene="narQ"
                     /locus_tag="ACHY1N_000477"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HFS4042828.1"
                     /translation="MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHL
                     NANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIG
                     IFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTSLPNELGLLAKTFNQM
                     SSELHKLYLSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRD
                     NEAAEYLELNVGENWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLN
                     SVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIP
                     EDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAK
                     LTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRD
                     NGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM
                     "
     gene            116259..118238
                     /gene="aegA"
                     /locus_tag="ACHY1N_000478"
     CDS             116259..118238
                     /gene="aegA"
                     /locus_tag="ACHY1N_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     AegA"
                     /protein_id="HFS4042829.1"
                     /translation="MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQHHFHPRITV
                     IKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSIQVNQQKCIGCKSCVVACPFGTM
                     QIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDVALSGMAKSRRLR
                     TARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRAD
                     QAQREASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITG
                     RVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSHVTKVDKRVAIIG
                     AGPAGLACADVLTRNGVAVTVYDRHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGI
                     HFELNCEVGKDVSLDSLLEQYDAVFVGVGTYRSMKAGLPNEDAPGVYDALPFLIANTK
                     QVMGLEELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPG
                     SKKEVKNAREEGANFEFNVQPVALELNEQGHVCGIRFLRTRLGEPDAQGRRRPVPIEG
                     SEFVMPADAVIMAFGFNPHGMPWLESHGVTVDKWGRIIADVESQYRYQTTNPKIFAGG
                     DAVRGADLVVTAMAEGRHAAQGIIDWLGVKSVKSH"
     gene            118306..118881
                     /gene="nudK"
                     /locus_tag="ACHY1N_000479"
     CDS             118306..118881
                     /gene="nudK"
                     /locus_tag="ACHY1N_000479"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HFS4042830.1"
                     /translation="MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDR
                     GNGATILLYNAKKKSVVLIRQFRVATWVNGNESGQLIETCAGLLDNDEPEVCIRKEAI
                     EETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDNQRANAGGGVEDEDIEVLELPF
                     SQALEMIKTGEIRDGKTVLLLNYLQTSHLMD"
     gene            119007..120050
                     /gene="ypfG"
                     /locus_tag="ACHY1N_000480"
     CDS             119007..120050
                     /gene="ypfG"
                     /locus_tag="ACHY1N_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HFS4042831.1"
                     /translation="MRYRIFLLFFFALLPTSLVWAAPAQRAFSDWQVTCNNQNFCVAR
                     NTGDHNGLVMTLSRSAGAHTDAVLRIERGGLKSPDASEGEIAPRLLLDGEPLALSGDK
                     WRISPWLLVTDDTATITAFLQMIQEGKAITLRDGNQTISLSGLKAALLFIDAQQKRVG
                     SETAWIKKGDEPPLSVPPAPALKEVAVVNPTPTPLSLEERNDLLDYGNWRMNGLRCSL
                     DPLRREVNVTALTDDKALMMISCEAGAYNTIDLAWIVSRKKPLASRPVRLRLPFNNGQ
                     ETNELELMNATFDEKSRELVTLAKGRGLSDCGIQARWRFDGQRFRLVRYAAEPTCDNW
                     HGPDAWPTLWITR"
     gene            complement(120146..122149)
                     /gene="tkt"
                     /locus_tag="ACHY1N_000481"
     CDS             complement(120146..122149)
                     /gene="tkt"
                     /locus_tag="ACHY1N_000481"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFS4042832.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGH
                     DPQAVKEAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKL
                     GWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPK
                     DWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGS
                     VSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAVEQLASLRLTPNFSTWRPCDQVEAAVGWKLAVER
                     HNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEMEITLQA
                     AEKLAGEGRNVRVVSLPSTDIFDAQDEEYRESVLPSNVAARVAVEAGIADYWYKYVGL
                     KGAIVGMTGYGESAPADKLFPFFGFTAENIVAKAHKVLGVKGA"
     gene            complement(122169..123119)
                     /gene="tal"
                     /locus_tag="ACHY1N_000482"
     CDS             complement(122169..123119)
                     /gene="tal"
                     /locus_tag="ACHY1N_000482"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004801 - transaldolase activity [Evidence
                     IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HFS4042833.1"
                     /translation="MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGL
                     SQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSF
                     DKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
                     AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYE
                     TIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMS
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            123408..125687
                     /gene="maeB"
                     /locus_tag="ACHY1N_000483"
     CDS             123408..125687
                     /gene="maeB"
                     /locus_tag="ACHY1N_000483"
                     /EC_number="1.1.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HFS4042834.1"
                     /translation="MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVV
                     CDSKGVIYQGREPNMAETKAAYAVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEG
                     EEARVLHATQELVTLGLAKPILIGRPNVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWTEYFQIMKRRGVTQEQAQRALISNPTVIGAIMVQRGEADAMICGTVGDYHEHFSV
                     VKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFG
                     IEPRVALLSHSNFGSSDCPSSSKMRQALELVRDRAPDLMIDGEMHGDAALVEAIRNDR
                     MPDSPLKGSANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVAKPVHVLTPIASV
                     RRIVNMVALAVVEAQTQPL"
BASE COUNT        30122 a        31813 c        33848 g        29985 t
ORIGIN      
        1 tctaccatgc ttattggcta tgtacgtgtg tcaacaaatg accagaacac agatctacaa
       61 cgtaatgcgc tgaactgtgc aggatgcgag ctgatttttg aagacaagat aagcggtaca
      121 aagtccgaaa ggccggggct gaaaaaactg ctcaggacat tatcggcagg tgacactctg
      181 gttgtctgga agctggatcg gctggggcgc agtatgcggc atcttgtcgt gctggtggag
      241 gagttgcgcg aacgaggcat caactttcgt agtctgactg attcaattga taccagcaca
      301 ccaatgggac gctttttctt ccatgtgatg ggtgccctgg ctgaaatgga acgtgaactg
      361 attgttgaac gaacaaaagc aggactggaa gctgctcgcg cacagggacg aattggtgga
      421 cgacgtccca aacttacacc agaacaatgg gcacaggccg gacgattaat tgcatcagga
      481 gttcctcgcc tgaaggtagc gatcatctat gatgttggca tatcgacttt gtataagagg
      541 tttccggtgg gagataaatg aaaccgtagc acgtcgtatg caagaacgtg ctgcggttgg
      601 ctgataagct tgtaaaaata ttgaacaggg agtggagcat tctatgaagc taatttgttt
      661 aatttcattt gtagtgactt tacttcttgg tcgataatgt tgaatccctt attgactgca
      721 tctcttagct ctgcatcaat attttttatc ccttgagcat aatctaccat tacatttatt
      781 tttgcatcat gtaatctctt atacatggtt ttatctttgt tattgtctgc catgccaata
      841 aggatttttt cataatcctc aatgagtttg ttgtttcctt taaatgattg tattaatgag
      901 cgtgaatatg tgtatatgtt aattattgag tctctagcag aatcatttag ttttgcaatg
      961 acattcgcat tttgctcata gaatgtgaaa ttatcatccc ctacagggaa tgtgagaatc
     1021 aacatttgtc ccggtttgat attatcaatg tgtgttttca tccttttatt atataaattg
     1081 attagggtga aaacttctcc cttaactcct tttaatactg aaagttgtaa ttcaagggat
     1141 tctctttctg tctctacttt agacagctta gcttgttggg taactccttt tagggtaaac
     1201 catccgccaa taagagtacc aactagagct gtgagggagg aggataacca tccaggaatg
     1261 ctatttaaaa gattactaaa ttcactcatt ataagtactc gctaatattg aacgatatat
     1321 atatcaaatt attataaaac tcgtcagcta ttggagaagg ctacctgaac ttcgatctat
     1381 tcctgcatcc atatagttga tggtcttctg gagctcttcg attagggcaa cagcttttgc
     1441 tcgagaaatg catattagtt gatccggaaa ttcttgtaag ggccagtttg gtatacaggc
     1501 catgttatca gtgaaggatg cagacaagta aacttcattg gtaaccagag aatagcttac
     1561 ctcaaaattg gtgagttccg gcaaactgct aacgtttgac tcttttctgc gcataatatt
     1621 atccatgact gtaattatgt acaggtgatg gtcttcaatt tcgaagaggg agtcaagggg
     1681 gagtctcaaa tgaaccgtta tagaaaaggg gggggatctt tgtgttgctg aacttatgca
     1741 aaattttttt gcaccataaa tccaacaaca cattcaataa cacattgctg tatcactatg
     1801 aaaataaatg tgtttttgtt ttatttcaca catatcacaa ttgatgcatt ttttagtgat
     1861 taacaacgcc ataaggaaac tctcaaaaca acacaaaccg ggcgggcatt atacgcgcat
     1921 tctttactca gaccagtttt ttcatcagcg cttcactctg acgaatacgt tctggtgcca
     1981 gttccagatc ctgctgaatc agcgcaatga acagcaaatc cgttaacatt ccctgagcgt
     2041 gacaagcaga gattgaagca ctgtttgtcg cttgttcttc ggcaatggta tacaggcaat
     2101 gagaagcacg ctgttgcagg gcattgggag taaagccggt aatcgccagc acttttccgc
     2161 ccactcgcag catctcatct gccgccaggt ttaactcgcg tcgtacaccg gtgtaggaaa
     2221 tggctaataa cagatcgtca ggggacgacg cctgtactgt tgcgagtagc gcatgcatat
     2281 cgcgcactgc ggcagcattg aagccaatct tcatcagctt ccaggcaaag ttttgcgcca
     2341 ccagacccga agcgccaata ccggtcagaa ttatccgccg cgcagagcgc aacattgtta
     2401 cgcattcatg cagtttctct tcactattaa cgtttagcgt tgcgtacata gcggcagtat
     2461 tttctttaat cagtttttcg ccgaccagcc gtaacggatc atcaccgcgg atttggttat
     2521 gaatgggcac ggagggcgat tccggctggc ttgccagcgc ttcactcaac gccaacttaa
     2581 gcgccggaaa acctttatag ccgagttttt gcgcgaactt cacgacgctg gactgactga
     2641 ctccggcttc gttggccagt tgctgagaac ttaaatggcg cgccgtatca ggttgtagca
     2701 gcagataatc cgccagtttt ttatcactct gggcaagccc ctggtaacgc tgacggatac
     2761 gaagtaagcc gttcatatct ttcctcgcga tgaaatagtg gcgacaacag gcaatatgag
     2821 acacacgcga gtgaatttta tattccattg ccgctaattg ccatgaatta aaaattccag
     2881 ttagccatga tgcggtcgat tgttgccgga aaagtgatga tctatctgtt aggctatgta
     2941 gtagcgaaaa ttaatcagga tgtttcagtc cagaggagta tggtttggca actcacgagc
     3001 gtcgtgtggt gttttttgac ttagatggaa cattgcatca gcaggatatg ttcggcagtt
     3061 ttctgcgcta tttactgcgt cgccaaccgc tgaatgcgtt acttgtcctg ccgttgttac
     3121 cgattatagc cattgcgtta ttgataaaag gtcgtgcggc acgctggccg atgagtctgc
     3181 ttctgtgggg gtgcactttt ggtcacagcg aagcacgttt acagacgttg caggccgatt
     3241 tcgtgcgctg gtttcgcgac aatgttaccg cctttccgct ggttcaggag cgattaacca
     3301 cctacctgtt aagttccgat gctgatatct ggttgattac cggctctccg cagccgctgg
     3361 ttgaagcggt ttatttcgat acgccctggc tgccgcgggt taatcttatc gccagccaaa
     3421 ttcagcgtgg ctatggtggt tgggtattga cgatgcgttg tctgggacat gaaaaggtcg
     3481 cacaactgga gcgcaaaatc ggcactccgc tgcggctgta cagtggctat agcgacagta
     3541 atcaggacaa tccgctgctt tatttctgtc agaatcgttg gcgagtaacc ccgcgcggtg
     3601 aactccagca actggaatag agtaaagcat agcgtccgtg tataatgcgc cgcgctttta
     3661 taaccggagt tttctttttg tctgaagtcg aatttagcca cgaatactgg atgcgtcacg
     3721 cgctgacgct ggcgaaacgt gcctgggatg agcgggaagt gccggtcggc gcggtattag
     3781 tgcataacaa tcgggtaatc ggcgaaggct ggaaccgccc gattggtcgc catgatccca
     3841 ccgcacatgc agaaatcatg gccctgcggc agggtggtct ggtgatgcaa aattatcgtc
     3901 tgatcgacgc cacgttgtat gtcacgcttg aaccatgtgt aatgtgtgcc ggagcgatga
     3961 tccacagtcg cattggtcgc gtggtctttg gtgcgcatga cgcgaaaact ggcgctgcgg
     4021 gatctttaat ggatgtgctg catcatccgg gtatgaatca ccgagtggaa attacggaag
     4081 gaatactggc ggatgagtgc gcagcgttgc tcagtgactt ctttcgcatg cgccgccagg
     4141 aaattaaagc gcagaaaaaa gcgcaatcct cgacggatta attttgtttc tcttcactcc
     4201 ctttcctgga aaacagcaga gagggagaat gggtcaaata gtttgatgac gactgggaaa
     4261 gaaacgagag aaaaggaaat ttctctttgc ccaactccgt aggcgatacc gccggataat
     4321 cctgcgccag ttgcatcgcc gcttctgtag cctgcttctc tttctcttgc agataaccca
     4381 ccaggctaat ctgatactta cgaatatttt cgacataagc gtaggcttca tgtccacgag
     4441 cgtagccgta agtcagcttg ctgtaatagg gtttctggct aagtaaaggc agacgctgtt
     4501 ttacgtcagc ccaactgtca ggattccctt tggtttttgc cgtcagggcg cgggcatcca
     4561 gcatatgcgc atagcccata ttgtacgcag cgagggcaaa ccagatccgc tcgttctccg
     4621 gcacactttc cggcacttta ctcatcatat cctgcaaata acgcacgcca ccgctgatgc
     4681 tctgttcggc atcggtacga tccgtaatgc cgaggctttg cgcggtattt ttggttaaca
     4741 tcatcatgcc gcgcacaccc gtcggtgaag tggcctgtgc atcccagtgc gattcctgat
     4801 aagcaatagc ggccagcaaa cgccagtcaa tttcttcggc gtatttctca aacaggggct
     4861 ttaactgcgg cagtaccgca tcgacggcgc gtaaaaatgt gcgcgtatcg acgtaatcaa
     4921 aatcatcgcc atgccccagg tatttctctt caatgcgtgc cagcgtaccg tcttcattca
     4981 tttcgttgaa gaagtcgagc agggcggcgg aaagggtatt atcgccatct aacgggctaa
     5041 accaagtcac cggttgttca tcggtgatat cgagcgctac ggcgagctcc gggtgaacgc
     5101 gctgaaacag gctgatggcg acagaatcag caatggtgta atcgagtttt ccttcgatga
     5161 catcttccat taattccgca gagccttttt tgtcgtctac cttccagctt aattccggga
     5221 attttgtttc tttcagggtc tggagatcgt taaccaccac atgacccggt gcaacggtga
     5281 gttgctccgc cgtcaggttg cccagcgtac gtgggcgata ctgacccact ttataaacca
     5341 gttgttgtga cacggaataa taggtagggc caggctgata attttttacc cgctcactgt
     5401 tatagaccag tcctgccgcc agcaggtcgg cgttaccatt atcaaggtcg tcaaacagct
     5461 ggctgatatt ctgccgcacg gtcactttca gttttacgcc gaggtaatcg gcaaactgtt
     5521 tcgccagttc gtaatccagg ccaaaaggtt tcccgttgat ttcgttataa gtcaggggag
     5581 tatgaatggt gctcacacgc aactctcccc gcgcttgaat ggcggcgata cggttgtcgg
     5641 ctttaccaaa ccagggaatg gatggccaga gagcgaccgc gagcagcagt gccagaatgc
     5701 cgatgaacag ataattaatc tttaattttt tcaattagtt aattctctgt gtcgtgcgcg
     5761 tcccagcttg aaaaaacgta ataatagtga aaggtttact cataaatgag cggcattttg
     5821 cgtaaacctg cgccagatgg caacttatta cagccattgg cggcacgcgt tgctaattca
     5881 cgatggtgat tttatttcca cgcaaacggt ttcgtcagcg catcagattc tttataatga
     5941 cgcccgtttc ccccccttgg gtacaccgaa agcttagaag acgagagact tatgatggaa
     6001 attctgcgtg gttcgcctgc actgtcggca ttccgaatca acaaactgct ggcacgtttt
     6061 caggctgcca ggctcccggt tcacaatatt tacgccgagt atgtccattt tgctgacctc
     6121 aatgcgccgt taaacgatga tgagcacgca caacttgaac gcctgctgaa atatggcccg
     6181 gcactcgcca gccacgcccc gcaaggcaaa ctcctgctgg tgaccccgcg tcctggcacc
     6241 atctctccct ggtcttcgaa agcgaccgat attgcccata actgcgggct acaacaggta
     6301 aaccgccttg agcgcggcgt tgcttactat atagaagccg gtacgctgac caatgaacaa
     6361 tggcagcagg ttaccgctga actgcacgac cgcatgatgg aaacggtctt ttttgcttta
     6421 gatgatgcag agcagctgtt tgcacaccat caaccgactc cggtcaccag cgttgatttg
     6481 ctggggcagg gccgtcaggc gctaatcgac gctaacctgc gtcttggcct ggcactggcg
     6541 gaagatgaaa ttgactatct gcaggatgct ttcacaaagc ttggtcgtaa cccgaacgac
     6601 atcgagctgt atatgttcgc ccaggcgaac tccgagcact gccgccacaa gatttttaac
     6661 gccgattggg ttatcgacgg tgagcaacag ccgaaatcgc tgtttaagat gatcaaaaac
     6721 accttcgaaa ccacgccaga ttacgttctc tctgcttata aagataacgc cgccgtaatg
     6781 gaaggttctg aagtgggccg ctactttgct gaccacgaaa cgggccgcta cgatttccat
     6841 caggaaccgg cgcatattct gatgaaagtc gaaactcaca accacccgac ggcgatttct
     6901 ccgtggccgg gcgcggcgac cggttccggc ggtgaaatcc gcgatgaagg tgccaccggg
     6961 cgcggcgcga agccgaaagc gggtttggtt ggtttctccg tttccaacct gcgaattcct
     7021 ggcttcgaac agccgtggga agaagatttc ggtaagcctg agcgcattgt caccgcgctg
     7081 gacatcatga ccgaaggccc gctgggcggc gcggcgttta acaacgaatt tggtcgtccg
     7141 gcactgaatg gctacttccg tacttatgaa gaaaaagtga acagccacaa cggcgaagag
     7201 ctgcgcggtt atcacaaacc gatcatgctg gcgggcggga tcggcaacat tcgcgccgat
     7261 cacgtacaaa aaggcgagat caacgtcggt gcgaagctgg tcgttctcgg cggcccggca
     7321 atgaacatcg gtcttggcgg cggagcggcg tcttccatgg cgtcaggtca gtctgatgcc
     7381 gacctcgact ttgcttccgt acagcgcgac aacccggaga tggagcgtcg ttgccaggaa
     7441 gtgatcgacc gttgctggca gcttggtgat gctaacccaa ttctgtttat ccacgacgtc
     7501 ggtgcgggcg gtctttctaa cgcgatgccg gagctggtga gcgacggcgg acgcggcggt
     7561 aaatttgaac tgcgcgatat tctaagcgac gaaccgggca tgagcccgct ggaaatctgg
     7621 tgtaacgaat cccaggaacg ctacgtgctg gcggttgctg ccgatcaatt accgctgttt
     7681 gacgaactgt gtaagcgtga gcgcgcaccc tacgcggtga ttggtgaagc gaccgaagaa
     7741 ctgcatcttt ctctgcacga tcgtcatttt gataatcagc cgatcgatct gccgctggac
     7801 gtcctgcttg gtaaaacgcc gaagatgacc cgcgatgtac aaacgctgaa agcgaagggc
     7861 gatgcgctgg tccgtgaagg gatcaccatt gcagacgcgg tgaaacgcgt actgcatctg
     7921 ccgaccgtgg cggagaaaac tttcctggtg accatcggtg accgcagcgt aactggcatg
     7981 gtagcgcgcg atcagatggt gggtccgtgg caggtgccgg tcgctaactg cgcggtcact
     8041 accgccagcc tcgacagcta ctacggtgaa gcgatggcga ttggcgagcg tgcgccggtt
     8101 gcgctgctgg atttcgccgc ctctgcccgt ctggcggtcg gtgaagcgtt aaccaatatt
     8161 gccgcaacac agattggcga tatcaaacgc attaaacttt ccgccaactg gatggcggcg
     8221 gcaggccacc ctggtgaaga tgcgggcctg tatgaagccg ttaaagccgt gggcgaagag
     8281 ctttgtccgg cgctgggcct gacgatcccg gtgggtaaag actctatgtc gatgaaaacc
     8341 cgctggcagg aaggtaacga agagcgcgaa atgacgtcgc cgctgtcgct ggtgatttct
     8401 gcatttgccc gcgtggaaga tgtacgtcac accatcacgc cgcagctttc taccgaagat
     8461 aacgcactgc tgctgattga tttgggcaaa ggcaataacg cgctgggcgc aacggcgctg
     8521 gcgcaggttt atcgtcagct tggcgacaaa ccggcagatg tacgcgatgt cgcgcaactg
     8581 aaaggcttct atgacgcgat tcaggcgctg gttgcacagc gtaagctgct cgcataccac
     8641 gaccgctctg atggcggcct gctggtaacg ctggcggaaa tggcctttgc tggtcattgc
     8701 ggcattaacg cggatattgc ctctctgggc gacgatcgcc tggcggcgtt gtttaacgaa
     8761 gaactgggtg cggtgattca ggttcgtgcc gctgaccgtg aagcggtcga gtccgtactg
     8821 gcacagcatg ggcttgctga ttgtgtccat tatgtagggc aggcggtttc cggtgaccgt
     8881 tttgtgatta ccgccaacgg gcagactgta ttcagcgaaa gccgcaccac gttgcgtgtc
     8941 tggtgggcag aaactacctg gcagatgcag cgcctgcgtg acaacccgga gtgtgctgac
     9001 caggagcacc aggcgaaatc aaacgacgcc gatccgggcc tgaatgtgaa actgtcgttc
     9061 gatatcaacg aagatgtggc agcaccgtat attgccactg gcgcacgtcc gaaagttgct
     9121 gtgctgcgtg agcagggcgt gaactcgcat gttgaaatgg cggcagcttt ccaccgtgca
     9181 ggcttcgatg caatcgatgt gcatatgagt gacctgctga ctggacgcac gggcctggaa
     9241 gatttccacg ccctggtcgc gtgcggtggt ttctcctacg gtgatgtgct gggtgccggt
     9301 gaaggttggg cgaagtcaat cctgttcaat gaccgtgtac gcgatgagtt tgcaaccttc
     9361 ttccaccgtc cgcaaacgct ggcgctgggg gtatgtaacg gttgccagat gatgtctaac
     9421 ctgcgcgaac tgatcccagg tagtgagttg tggccacgtt ttgtgcgcaa tacctccgat
     9481 cgctttgaag cgcgtttcag cctggttgaa gtgacccaaa gcccgtcgct gctgttgcag
     9541 gggatggtgg gctcgcaaat gccgattgct gtctctcatg gtgaagggcg cgtggaagtg
     9601 cgtgatgcgg cgcatctggc ggcactggaa agcaaagggc tggtggcact gcgctatgtc
     9661 gataacttcg gcaaagtcac tgaaacctac ccggctaacc cgaacggttc accgaacggt
     9721 attacgtcga ttacgactga aagtggtcga gtcaccatta tgatgccgca cccggaacgt
     9781 gttttccgta ctgtcagcaa ctcctggcat ccggaaaact ggggcgagga tggcccatgg
     9841 atgcgcattt tccgcaatgc gcgtaagcag ttggggtaag tcatcagttc attggttttg
     9901 cagcccggat gcggcattta cgccgcatcc ggcattaagc accaaccact atcataagct
     9961 cccaactccg ggagcttttt tgtgtctgta aatcacgaca atgggtggtt taccgtgtcg
    10021 ctttctggcg acacttaact cattgatttt aatattatct aataagttta tcttaagttg
    10081 tctcttttta gcgacacagt ggctgattta cattcaaata acggagaagc cataaacccc
    10141 tcaaagcgac gtataatcag tacgttacca aactattttc tttattggca cagttactgc
    10201 atatagtaag cagtggctca ttcaccgact tatgtcagcc ccttcgggac gtgctacata
    10261 aaattcgaat gacgcacaac aaggtgcctg ccgtccaact tctgatatca gcgtagctat
    10321 atcaaccatc gggcgaaacg tcgagttagg caccgcctta ttccataaca aagccgggta
    10381 attcccggct ttgttgtatc tgaacttccc ctcggttagc atcaggctat tcgcgtctga
    10441 cgagagtaac accttgaaac gctggcctgt ttttccccgc tcattacgac aactggtaat
    10501 gctggcattt ttgctaattc tactacccct gttggtgctg gcatggcaag cctggcaaag
    10561 cctgaatgcg cttagcgatc aggcggcgct ggttaaccgc actacgctta ttgatgcccg
    10621 gcgtagtgaa gcgatgacca acgcggcgct ggagatggag cgtagctacc gtcagtattg
    10681 cgtgctggac gatcctacgc ttgcgaaggt ttatcaaagc cagcgcaagc gttacagcga
    10741 aatgctcgat gcccacgcag gcgtactgcc agacgataaa ctttaccagg cattgcgtca
    10801 ggatttgaac aatctggccc aacttcagtg taacaacagt ggtcccgatg ctgccgccgc
    10861 cgcgcgtctt gaagcctttg ccagtgccaa taccgaaatg gtgcaggcca cgcgcacagt
    10921 ggtgttctct cgtgggcagc aacttcagcg tgaaatcgcc gaacgtgggc aatattttgg
    10981 ttggcaatcg ctggtgctat ttctggtgag tctggtgatg gtgctacttt tcacgcggat
    11041 gattatcggg ccggtgaaaa atatcgagcg catgatcaac cgtctggggg aagggcgttc
    11101 tctgggcaat agcgtttcgt tcagtggacc gagcgagtta cgctcggttg ggcaacgtat
    11161 tctttggtta agtgagcgcc tgtcatggct ggaatcccaa cgccatcaat ttttaagaca
    11221 tttatctcat gaattaaaaa cgccactggc gagtatgcgc gagggcactg aattactggc
    11281 tgaccaggtt gtcgggccgc ttacgccaga gcaaaaagag gtggtgagca ttcttgatag
    11341 cagcagccgc aatttgcaaa aactgatcga acaactgctt gattacaacc gtaaacaggc
    11401 ggacagtgcg gtggaactgg agaatgttga attagcaccg ctggtggaga cagtggtttc
    11461 tgctcatagc ctgcccgcac gggctaaaat gatgcatacc gacgtcgatc tcaaagcaac
    11521 agcttgcctg gcggagccaa tgctgctgat gagcgtactg gataatcttt actccaatgc
    11581 ggtgcactac ggggctgaat ccggtaacat ttgccttcgc agcagttcac atggtgcgcg
    11641 ggtttatatt gatgtcatca ataccggcac gccaattccg caagaggaac gcgccatgat
    11701 cttcgaaccc ttttttcagg gaagccacca gcgaaaaggg gcggtgaagg gcagcggtct
    11761 gggattaagc attgccaggg attgtattcg ccgtatgcaa ggggaactgt atctggtcga
    11821 cgagagcggg caagacgttt gtttccgcat tgaattaccg tcgtcgaaaa acacgaaata
    11881 atgctaacag cctatcctat caggctattt tatttgtcag ttcggccccg ggcagtgctc
    11941 gaaatcttca cgtacgatat gtacgctccg gtttctccgc gctgtccatg tccagactgt
    12001 ctgcaacaat tacgcccact gggataggct ttaagtctgg tgaatatgcg acacattttt
    12061 caacgattat tgccccgacg gctgtggctg gcagggctgc catgtctggc attgctgggt
    12121 tgcgtgcaga atcacaataa gccagccatt gatacgccag cagaagaaaa aattccggtt
    12181 tatcaactgg ctgactatct ttctactgaa tgtagcgaca tctgggcgct gcaaggtaaa
    12241 tcaaccgaaa ccaatccgct ttactggctg cgggcgatgg attgtgctga tcgtttaatg
    12301 cctgcgcagt cgcgtcagca agctcgccaa tatgacgacg gcagctggca aaataccttt
    12361 aaacaaggga ttttgctcgc cgacgccaaa attacgccgt atgagcgccg ccagctggtc
    12421 gcgcgtattg aagcgttaag taccgagatc ccggcacagg ttcgcccact gtatcaactc
    12481 tggcgcgacg gtcaggcgct gcaactgcaa ctggcggaag agcgccaacg ttacagtaaa
    12541 ctccagcagt ccagcgacag cgagctggat acattgcgcc agcaacatca cgttctacag
    12601 cagcaactgg aactcaccac ccgcaagctg gaaaacctga ccgatattga acgccagctc
    12661 tcgacccgca aaccggctgg aaatttctcg ccggatacgc cgcacgagag tgaaaagccc
    12721 gcgccatcca cccatgaggt cactcctgat gagccataaa cctgcgcatt tattattggt
    12781 cgatgacgat ccgggattgc tgaaactgct tggcctgcgc ctgaccagcg aaggctacag
    12841 tgtggtcacg gcggaaagtg gcgctgaagg attacgggta ctgaatcgcg aaaaagtaga
    12901 tttagttatc agcgacctgc ggatggatga aatggacggt atgcagctat ttgctgaaat
    12961 ccagaaagtg cagccgggaa tgccagtaat tattcttact gcgcatggtt ctatccccga
    13021 tgccgttgct gcaacacagc agggcgtttt tagtttcctc accaagcctg tcgacaaaga
    13081 cgcgctatat caggcaattg acgatgcgct ggagcaatcc gcgccagcca ccgatgaacg
    13141 ctggcgcgag gcaattgtca cccgcagccc gctgatgctg cgtttgctgg aacaggcgcg
    13201 gctggtggcg caatcagacg tcagcgtttt gattaacggt cagagcggca ccgggaaaga
    13261 gattttcgcc caggctatcc acaacgccag cccgcgcaac agcaaaccat ttattgctat
    13321 taactgtggc gcattgcccg agcaattgct ggagtcggag ctgtttggtc atgcgcgtgg
    13381 cgcgtttact ggcgctgtca gcaatcgcga aggtttattc caggcggcgg aaggcggaac
    13441 gctatttctc gatgaaattg gcgatatgcc tgcgccgtta caggtcaaac tgctgcgcgt
    13501 gttgcaggag cgtaaagtgc gcccgctggg cagcaaccgc gatattgata tcgacgtgcg
    13561 gattatttct gccactcacc gtgatctgcc aaaagcgatg gcgcgcgggg aattccgcga
    13621 agatctctat taccgcctca acgttgtcag cctgaaaatt ccggctctgg cagagcgcac
    13681 agaagacatt ccgcttctgg caaatcacct gttgcgccag gcggcagagc gacataaacc
    13741 gtttgtccgc gcgttctcca ctgatgcgat gaaacgcctg atgaccgcta gctggccggg
    13801 taatgtgcgc cagttggtca acgtgattga acagtgcgtg gcgctgacct catctccggt
    13861 tattagcgat gcattagtag agcaggcgct ggagggtgaa aacacggcgc tgccaacctt
    13921 tgttgaggca cgtaatcagt ttgaactcaa ctatttgcgt aagctgctgc aaattaccaa
    13981 aggcaacgtc acccacgcgg cgagaatggc ggggcgcaac cggacagaat tttataaact
    14041 gctttcccga cacgagctgg atgcaaacga tttcaaggaa tgaattggcg ttatgtgtta
    14101 cgtttagcag atcaaaagac aggcgacctt ttcaaggaat agcatgaaaa agattgatgc
    14161 gattataaaa cccttcaagc tggacgatgt ccgcgaagca ctggccgaag tcggtattac
    14221 cggcatgacg gtgaccgaag tgaaaggctt tggtcgccag aaaggccata ccgagctgta
    14281 ccgcggcgcg gagtatatgg tggattttct gccgaaagtg aaaattgaga ttgtcgtacc
    14341 ggacgacatt gtcgatacct gtgtcgatac cattattcgc acggcgcaaa ccggcaaaat
    14401 cggtgacggt aaaatcttcg tctttgacgt ggcacgggtc attcgcatcc gtaccggtga
    14461 agaggacgac gcggcaattt aaaccgcgtc aagggttgcc ggatgtttcc atccggcaac
    14521 atcaaatcac agcaccttat gcgggccaaa gcattcgtaa tgaatgtttt cctgcttcac
    14581 gcccagatcc actaactgtt tcgcggcaaa ctgcatgaag ccaaccgggc cgcagagata
    14641 gaactgcatt gtcggatcgc tgaacgcacc ttcctgtttg ctcaaatcca tcagaccttc
    14701 gctatcaaac tgacctttag cgcgatcggc ttcgctcggc tgacgatacc aggtgtgcgc
    14761 ggtaaagcgc ggcagtgact gccccagttc cttaacttca tcggcaaagg cgtgaacatc
    14821 gccattttct gccgcatgga accagttcac ttgtgctgtg tggcctgctt ttgccagcgt
    14881 gtcgagcatt gccagcattg gcgtttgacc aacaccggca gagattaacg tcactggtgt
    14941 gtcatctgcg acagccataa agaaatcacc tgccggagcg accagtttca cgacatcgcc
    15001 aacattggcg tgattgtgca accagttgga tacctgccca ccctcttcgc gtttcaccgc
    15061 aatacgatag cctttgccat ccggtttgcg agtcaaagag tactgacgaa tttcctgatg
    15121 cgggaaacct tccggcttca gccagacgcc gagatattgc cccggacggt attctgccac
    15181 tgcgccaccg tcgaccggct ccagttcgaa gctggtgata agcgcgctgc gcggtgtttt
    15241 agccacaatg cggaaatcgc gagtaccttc ccaaccaccg gctttgctgg cgttttcgtt
    15301 atagatttcc gcctcgcgat tgataaatac attagccagt acaccatagg ctttacccca
    15361 cgcgtccagc acttcctgcc ccgggctgaa catttcgtcc agcgttgcca acaggtgttc
    15421 accgacgatg ttgtactgtt ccggtttgat ctggaagctg gtgtgcttct gcgcgatttt
    15481 ttctaccgct ggcagcagcg caggcaggtt ttcaatatta ctggcgtagg cggcaatagc
    15541 gttaaacagg gcttcacgtt gatcgccatt acgctggtta ctcatgttaa aaatttcttt
    15601 gagttctggg ttatgagtaa acatacggtc gtagaaatgg gcggttaact ttggccccgt
    15661 ttccaccagt aaagggatgg tggcttttac tgtagcgatg gtttgagcgt caagcatatg
    15721 gtcttccttt ttttgcatct taattgatgt atctcaaatg catcttataa aaaatagccc
    15781 tgcaatgtaa atggttcttt ggtgtttttc agaaagaatg tgatgaagtg aaaaatttgc
    15841 atcacaaacc tgaaaagaaa tccgtttccg gttgcaagct ctttattctc caaagccttg
    15901 cgtagcctga aggtaatcgt ttgcgtaaat tcctttgtca agacctgtta tcgcacaatg
    15961 attcggttat actgttcgcc gttgtccaac aggaccgcct ataaaggcca aaaattttat
    16021 tgttagctga gtcaggagat gcggatgtta aagcgtgaaa tgaacattgc cgattatgat
    16081 gccgaactgt ggcaggctat ggagcaggaa aaagtacgtc aggaagagca catcgaactg
    16141 atcgcctccg aaaactacac cagcccgcgc gtaatgcagg cgcagggttc tcagctgacc
    16201 aacaaatatg ctgaaggtta tccgggcaaa cgctactacg gcggttgcga gtatgttgat
    16261 atcgttgaac aactggcgat cgatcgtgcg aaagaactgt tcggcgctga ctacgctaac
    16321 gtccagccgc actccggctc ccaggctaac tttgcggtct acaccgcgct gctggaacca
    16381 ggtgataccg ttctgggtat gaacctggcg catggcggtc acctgactca cggttctccg
    16441 gttaacttct ccggtaaact gtacaacatc gttccttacg gtatcgatgc taccggtcat
    16501 atcgactacg ccgatctgga aaaacaagcc aaagaacaca agccgaaaat gattatcggt
    16561 ggtttctctg catattccgg cgtggtggac tgggcgaaaa tgcgtgaaat cgctgacagc
    16621 atcggtgctt acctgttcgt tgatatggcg cacgttgcgg gcctggttgc tgctggcgtc
    16681 tacccgaacc cggttcctca tgctcacgtt gttactacca ccactcacaa aaccctggcg
    16741 ggtccgcgcg gcggcctgat cctggcgaaa ggtggtagcg aagagctgta caaaaaactg
    16801 aactctgccg ttttccctgg tggtcagggc ggtccgttga tgcacgtaat cgccggtaaa
    16861 gcggttgctc tgaaagaagc gatggagcct gagttcaaaa cttaccagca gcaggtcgct
    16921 aaaaacgcta aagcgatggt agaagtgttc ctggaacgcg gctacaaagt ggtttccggc
    16981 ggtactgata accatctgtt cctggttgat ctggtcgata aaaacctgac cggtaaagaa
    17041 gcagacgccg ctctgggccg tgctaacatc accgtcaaca aaaacagcgt accgaacgat
    17101 ccgaagagcc cgtttgtgac ctccggtatt cgcgtgggta ctccggcaat tacgcgtcgc
    17161 ggcttcaaag aagcagaagc gaaagaactg gctggctgga tgtgtgacgt gctggacagc
    17221 atcaatgatg aagccgttat cgagcgcatc aaaggtaaag ttctcgacat ctgcgcacgt
    17281 tacccggttt acgcataagc gaaacggtta atctgttgaa aaaaggcttc cttcgggaag
    17341 cctttctacg ttatcgcgcc atcaaatctg tcgtaactgc gcctcaacat acaaatagcc
    17401 aattcccagc acctgttgtg cgcggcttaa ttgcccaaag ccaatttgcg tcgctttcac
    17461 gctcggtcct tcgtcgcggt cgaacgggtt aaatcctgtc tggcgaataa tagtattaag
    17521 ccagttctca ccaaaggcac aactgcgacc gtacaaccaa atctgattaa tattgaggat
    17581 gttgaggaag ttatacagac tcaaaccaat ggcattggca gagcgatcaa cccagctggt
    17641 gatccacggt tctccactct gccaggcagc gattaactgc gcggttgtca gtttttcagg
    17701 atcaagctga gtattaaccg gttgtgattt tagccatacc cgcgcctgtt tttttaatgc
    17761 acttaacgag gcgacggttt ccaggcagcc gtaacgtcca cagtcgcaga cgacgccatc
    17821 cggattaacg atggtgtgac caatctgtcc gctaccatac aaactgccgc gataaatttg
    17881 ctcgttaatc acgaacgacg agccaatgcc gtaatcaacg ttgatcacgc agaaatcccg
    17941 ttcctgcgaa ttattttgcc atttctccgc cagcgccagc atcacgcagt cattatcgac
    18001 catcacccga atgcccagct tctcttccag cagatacttc acctcaaccg gcgttgtcca
    18061 cggcgcttgc ggcatggttt gcgatacgcc ggtcaccgga tcaacctgcc cgtggattgc
    18121 cagcgccaga ttgatggtgc ggcccggcca cagtttgcga tgacgatgcc agcatttttc
    18181 gatttcggac agcagcgcct gcggcgtcgg tgcatcaatc tgtaaatact caaattcacc
    18241 tttcggactt aaacaagcat tagcaacctg acactcaata ctggtgggcg ttacgttcag
    18301 gcacagcgtc cagtcacctt ccggcgcaat cagccatgta ccgctactat gcccgcgcgt
    18361 ctggctttca tcgtcaatat tcaccacccg tttttcgctt tccagttcct gcaaaatatt
    18421 actgactgcc ggaatcgaaa tttgcgccag ccgggccagc gttgatttat tggcgcgctt
    18481 ttgccggtac agcagttcca gaatcacgca tttgttatgg tggcgaatct gttgattgtt
    18541 aatgcaggct ctcatcttca ctaaaccttg tttagttaat tgcgtgatta ttccgcgaaa
    18601 acattgccag attgttcaat acactgccac aaatctttta attcagtatg tcttgttaat
    18661 attgagggca ccatgactcc agtaaaagtg tggcaagagc gcgttgagat cccgacctat
    18721 gaaaccgggc cgcaggatat acatcccatg ttcctggaaa atcgcgttta tcagggatcg
    18781 tccggcgcgg tttatcccta cggcgtgacc gatacgctga gcgagcagaa aaccctgaaa
    18841 tcctggcagg cggtgtggct ggaaaacgac tacatcaaag tgatgatcct gccggaactg
    18901 ggcggtcggg tgcatcgcgc gtgggataaa gtgaaacagc gcgattttgt ttatcacaat
    18961 gaagtcatta aacctgcgct ggtggggctg ctggggccgt ggatttccgg tgggattgag
    19021 tttaactggc cgcaacatca tcgcccgacc acctttatgc ccgttgattt caccctcgaa
    19081 gcccatgaag acggtgcaca gacggtgtgg gtaggcgaaa cggagccgat gcatggttta
    19141 caggtgatga caggtttcac cctgcgccct gaccgggcgg cgctggaaat cgccagccgc
    19201 gtctataacg gtaacgccac gccgcgtcat ttcttgtggt gggccaaccc ggcagtgaaa
    19261 gggggggaag ggcatcagag cgttttcccg ccggatgtaa cggcggtgtt tgatcacggc
    19321 aaacgggccg tctccgcttt ccccatcgcc accggcactt actacaaagt ggactactcc
    19381 gccggagtgg acatttctcg ctataaaaat gtgcccgttc caacctcata tatggctgaa
    19441 aaatcacagt acgattttgt tggcgcgtgg tgtcacgatg aagatggcgg tttgctgcac
    19501 gttgccaacc accatattgc gccaggtaaa aaacagtgga gttggggaca cagtgaattt
    19561 ggccaggcgt gggataagag tctgaccgac aataacggcc cgtatatcga actgatgacc
    19621 ggtatttttg ccgataacca gcccgatttt acctggcttg atgcttacga agagaagcgt
    19681 tttgagcagt atttcctgcc ttatcattct ttgggcatgg tgcaaaatgc ctcccgcgat
    19741 gcggtgataa aactccagcg tagtgagcgg gggattgagt gggggctgta tgccatctct
    19801 ccgttgaacg gataccgcct ggcgatccgc gaaatcggca aatgcaacgc gttacttgat
    19861 gatgccgtgg cactgatgcc tgcgaccgcc atccagggcg tgttgcacgg tatcaatcct
    19921 gaaaggctga ccattgagct ctccgatgcc gacggcaata ttgtcctgag ttatcaggaa
    19981 catcagccgc aagagttgcc gttgccggac gtcgccaaag caccactcgc agcacaagac
    20041 attaccagta cagatgaagc ctggtttatc ggtcagcatc tggagcaata tcatcacgcc
    20101 agccgttcac cgttcgatta ctacctgcgc ggcgtggtgc tggatccgct ggattatcgc
    20161 tgtaacctgg cgctggcgat gctggaatat aaccgcgccg atttcccgca agcggtggcg
    20221 tatgccactc aggctctgaa acgcgcacat gcgctgaaca aaaatccgca gtgcggacag
    20281 gccagtttga ttcgcgccag tgcttacgaa cgtcagggac aatatcaaca agccgaagag
    20341 gatttctggc gtgcggtctg gagcggcaac agcaaagccg gtggctatta tggcctggca
    20401 cgactggcgg cgcgtaatgg taacttcgac gctggtctgg atttttgcca acaaagtctt
    20461 cgtgcctgcc caaccaatca ggaagtgctt tgcctgcata atctgctgct ggtgttaagt
    20521 ggtcgtcagg acaacgcgcg tttgcagcgc gcgaaactgc tgcgtgatta tccgctgaac
    20581 gccactctgt ggtggctgaa ctggttcgat ggtcgtagcg aatcagccct cgcgcagtgg
    20641 cgcggtctgt gtcagggacg cgacgttaac gctctgatga ccgccgggca actgattaac
    20701 tggggaatgc ccaccctggc ggcagagatg ctgaacgcac tggactgcca gcgcacgctg
    20761 ccgctttacc tgcaggcgag tttattgccg aaagccgaac gcggcgaact ggtcgcaaaa
    20821 gccattgatg tcttcccgca gtttgtccgt ttcccgaata cgctggaaga agtggcggcg
    20881 ctggagagta ttgaagagtg ctggtttgcc cgtcatttac tggcctgctt ctactacaac
    20941 aagcgtagct acaacaaagc cattacctta tggcaacgtt gcgtagagat gtcgccggag
    21001 tttgccgacg gctggcgcgg gttagcgatc catgcgtgga ataagcaaca cgattatgag
    21061 ctggccgcgc gttatcttga taatgcttat cagcttgcgc cgcaggatgc acgtctgctt
    21121 ttcgaacggg atttgcttga taagttaagc ggagccacac cggagaaacg actggcgcgt
    21181 ctggaaaata atctggaaat tgcgctgaaa cgcgacgaca tgacagcaga gttgctcaat
    21241 ttgtggcatc tcacgggtca ggcagacaaa gcggcggaca ttctcgccac gcgcaaattc
    21301 cacccgtggg aaggcgggga agggaaggtc accagtcagt ttatcctcaa ccagttatta
    21361 cgcgcctggc agcaccttga tgccagacag ccgcagcagg ccagcgaact gcttcatgcc
    21421 gcgctgcatt atccggagaa tttaagcgaa ggccgtttac cggggcaaac tgataacgac
    21481 atctggttct ggcaggcgat atgcgccaac gcgcagggcg atgaaactga agcgacgcgt
    21541 tgtttacgtc tggcggcgac cggcgatcgc accattaaca tccacagtta ttacaacgat
    21601 cagccggttg attatctctt ctggcaagga atggcgctgc gactgctggg cgaacaacaa
    21661 atcgcacagc aactgtttag tgaaatgaaa cagtgggcgc aagagatggc gaaaaccagt
    21721 attgaggcgg atttctttgc tgtttcacaa cctgacctgt tgtcgctgta tggcgattta
    21781 caacagcagc ataaagaaaa atgcctgatg gtggcgatgc tggcgtccgc gggactcggg
    21841 gaggttgcgc aatatgaatc tgctcgcgct gaattgacgg cgattaatcc ggcctggccg
    21901 aaagcggcat tattcaccac cgtgatgcct tttattttta actacgttca ctaaacccta
    21961 ttaactgtaa tatttgagcg gcacgcgctg ccgctcatca caaaataatt agaataagcc
    22021 gttgttaata aaaaccctac aggaggcact atgcctaaaa aaatgagaac aacccgtaat
    22081 ctattattaa tggctacgct attaggtagc gcactatttg ccagggctgc ggataaagaa
    22141 atgaccattg gtgcaatata ccttgatacc cagggatatt acgctggagt gcgtcagggc
    22201 gttcaggatg cggcaaaaga ttcttcagta caggtacagt taattgaaac taacgcccag
    22261 ggtgatattt cgaaagaaag tacctttgtt gataccctcg tggcgcgtaa tgtcgatgcc
    22321 attattttat cggcagtgtc tgaaaatggc agtagccgta ccgttcgtcg cgccagtgaa
    22381 gcgggtattc cggtgatttg ctacaacacc tgtattaatc aaaagggtgt cgataaatat
    22441 gtctcggcgt atctggtcgg cgatccactg gaatttggta aaaaactggg taacgctgcc
    22501 gccgattatt ttattgccaa taaaatttac cagccgaaaa ttgccgtcat caattgcgaa
    22561 gcctttgaag tttgtgtgca gcgacgtaaa ggatttgaag aagtattaaa atcccgcgtt
    22621 cccggcgcgc aaattgtcgc taatcaggaa gggactgttt tagataaagc gatttccgtt
    22681 ggtgaaaaac tgattatctc cacgccggat ctcaacgcca ttatggggga gtcgggcggt
    22741 gcgacactcg gcgcggtaaa agcggtacgt aatcaaaatc aggccggaaa aattgctgtt
    22801 ttcggttcgg atatgacaac cgaaattgct caggagctgg aaaacaatca ggtgctgaaa
    22861 gcggtagtgg atatttccgg taagaaaatg ggcaatgctg ttttcgcgca aacattgaag
    22921 gttatcaata aacaagccga cggtgaaaaa gtgattcagg tgccaatcga tctctatacc
    22981 aaaacggaag atggtaaaca gtggctggca acgcacgttg atggtctgcc ctaatcgctg
    23041 attcgcagag gtccctatgt ttacggcaac agaggcagtc ccggtagcaa aagtggtggc
    23101 aggaaataag cgttaccccg gcgtcgttgc gctggataac gttaacttca cgctcaataa
    23161 aggcgaagtt cgtgcgctgt taggtaaaaa cggcgcgggc aaatcgactc tcattcgaat
    23221 gcttaccggc agcgaacgcc cggatagcgg tgatatctgg attggcgaga cgcgactgga
    23281 aggtgacgaa gctacgttga ctcgccgtgc cgctgaactg ggggttcgtg cggtttatca
    23341 ggaattaagt ctggtggaag ggctgacggt ggcagaaaac ctctgccttg gtcaatggcc
    23401 tcgccgcaac ggcatgattg attacctgca aatggcgcag gatgcccaac gttgcttaca
    23461 ggcgctgggc gttgacgtta gtcctgaaca acttgtttca acgctaagcc cggcgcaaaa
    23521 gcaactggtg gaaattgcac gggtgatgaa gggcgagccg cgcgtggtca ttcttgatga
    23581 acccaccagc tcgcttgcca gtgcagaagt tgaactggtg atcagtgcgg tgaaaaagat
    23641 gtcggcactg ggcgtggcgg tgatttatgt cagccaccgg atggaagaaa tccgccgcat
    23701 tgcctcctgt gccaccgtta tgcgcgatgg tcaggtggcg ggcgatgtga tgctcgaaaa
    23761 cacctccacg catcatattg tgtcgctaat gctagggcgt gatcacgttg atattgcgcc
    23821 ggttgcccct caggaaattg tggatcaggc cgtactggaa gtccgtgcgt tacgccataa
    23881 gcccaagctg gaggatatca gctttacgtt acgtcgcggc gaagtgcttg gcattgctgg
    23941 cctgctgggg gcagggcgca gtgaattgct gaaggcgatt gttgggctgg agacgtatga
    24001 acagggcgaa attgttatca acggcgagaa aatcacgcgc cccgattacg gcgacatgct
    24061 gaaacgcggc attggctata cgccagaaaa ccgcaaagaa gcggggatca ttccctggtt
    24121 gggcgttgac gaaaatacag tgctgaccaa tcggcaaaaa atcagcgcca acggagtgct
    24181 gcaatggtcc accatccgcc gcctgaccga agaggtgatg cagcggatga cggtcaaggc
    24241 cgccagtagc gaaacgccca tcggcacgct ttctggtggc aatcagcaaa aagtggtgat
    24301 cggtcgttgg gtctatgccg ccagccagat tttgttgctc gacgagccaa cgcgcggcgt
    24361 cgatatcgaa gccaaacagc agatttaccg tattgtccgt gagctggctg ccgaaggaaa
    24421 aagcgtggtg tttatctcca gtgaagtgga ggagttgccg ctggtgtgcg accgcatcct
    24481 gttgttacag cacggtacgt tctcgcagga gtttcactcg ccggtcaatg tggatgagct
    24541 gatgtccgcc attctgtctg tgcactgatg aattttaccg aggaacctga agatgtctgc
    24601 ttcgtcatta tcattgccgc agggcaagag cgtctcgctc aaacaatttg tcagtcgcca
    24661 tattaatgag atcggtttgc tggtggtaat cgccattctt tatctggtct tctccctgaa
    24721 tgcgcctggc tttatctcat tgaataacca gatgaacgtg ctgcgcgatg ccgccaccat
    24781 tgggattgcc gcctgggcga tgacgctgat tattatctcc ggtgaaattg atgtcagcgt
    24841 tgggccgatg gtggcttttg tctcggtgtg cctggcattt ttgctgcaat ttgaagttcc
    24901 gctggcggtg gcgtgtctgc tggtgttgct gttaggcgcg ctgatgggaa cgctggccgg
    24961 ggtgctgcgc ggcgtgttta acgtaccaag tttcgttgcc acactggggc tgtggagcgc
    25021 cctgcgcgga atggggctgt ttatgacgaa cgcactgcca gtgccgattg acgaaaacga
    25081 ggtgctggac tggctgggcg gacaatttct cggtgtgccg gtatccgcgc tgatcatgat
    25141 tgtgttgttt gcgctgtttg tgttcatcag ccgcaaaacc gccttcgggc gctcggtttt
    25201 tgccgttggc ggtaatgcta cggcggcgca gttgtgcggc atcaacgttc gtcgggtgcg
    25261 cattcttatc tttacccttt cgggattatt agcggcggtg accggcattt tgttggcggc
    25321 gcgcctcggt tctggtaacg caggtgccgc aaacggtctg gagtttgacg tcatcgccgc
    25381 ggtcgtggtc ggcggtacgg cactttccgg cggtcgcggt tccctgttcg gtacattgct
    25441 tggtgtgctg gtgattacgc taatcggtaa cggtctggtg ctgctcggta ttaactcctt
    25501 tttccagcag gtggtacgcg gcgtcatcat cgtggtggcg gtgctggcga atatcttgct
    25561 gacccagcga agcagtaaag cgaaacgcta aaccttaacg cccctggcgc gggtgcggca
    25621 gggatgaaaa ttaatcgtat tgttaatgag ggatttatga aaacgatgct ggcagcttat
    25681 ttaccaggaa attcaaccgt cgatctgcgg gaagttgcgg tgccgacgcc ggggattaac
    25741 caggtactga tcaaaatgaa atcctccggg atttgcggaa gcgatgtcca ctatatctat
    25801 catcaacacc gtgccacggc ggcggcaccc gataaaccgt tataccaggg atttatcaac
    25861 ggtcatgaac cgtgcgggca gattgtggcg atggggcaag gctgtcgcca ttttaaagag
    25921 ggtgatcgcg tgctggtgta tcacatttct ggctgtggtt tttgcccgaa ctgccgccgc
    25981 ggctttccta tctcttgtac tggcaaagga aaagcggctt acggctggca gcgtgacggc
    26041 ggtcatgccg aatatctgct ggcggaagaa aaagatctga tcctcctgcc ggatgcgctg
    26101 agctacgaag atggtgcgtt tatcagttgc ggcgttggca cggcctatga agggattttg
    26161 cgcggcgaag tttccggcag cgataacgtg ctggtggtcg gtctggggcc ggtcggcatg
    26221 atggcgatga tgctggcgaa aggtcgcggt gcaaaacgga tcatcggcgt tgatatgctg
    26281 ccggaacgtc tggcgatggc aaaacagtta ggggtgatgg atcacggcta tttagcaacc
    26341 accgaaggtc tgccgcagat tatcgccgaa ctcacccacg gtggcgcgga tgttgcgctc
    26401 gattgttccg gtaatgccgc aggtcgcttg ctggcactgc aatccaccgc tgactgggga
    26461 cgggtggttt acattggtga aaccggaaaa gtggaattcg aggtcagcgc cgatctgatg
    26521 caccatcaac ggcggattat cggctcctgg gtgaccagtc tgttccatat ggaaaaatgc
    26581 gcccatgatc tgacggactg gaagctgtgg ccgcgtaacg ccattaccca tcgcttctcg
    26641 ctggaacagg caggtgatgc ctatgcgctg atggcgagcg gcaaatgcgg gaaagttgtg
    26701 attaacttcc cggattaagg agttagcgga tgaccatcta taccttatcc cacgggtcgc
    26761 taaagctgga cgtttctgac cagggcggcg taatcgaagg cttctggcgc gatacgacgc
    26821 cgctcttacg tcctggtaaa aaaagcggtg tggcaaccga tgcctcatgt tttccgctgg
    26881 tgccatttgc aaaccgggtg agcggcaatc gttttgtctg gcaggggcgt gagtatcaac
    26941 tgcaaccgaa tgttgagtgg gatgcgcact atctacacgg cgatggctgg ctgggcgagt
    27001 ggcaatgtgt ctcgcacagc gatgatagtt tgtgtctggt gtatgaacat cgcagcggtg
    27061 tctatcacta tcgggtaagt caggcgtttc atttaacggc ggatacgctg acggtgacgc
    27121 tctctgtcac caatcaaggg gcagagacgc tgccatttgg taccggctgg catccttatt
    27181 ttccgttgtc gccgcaaacg cggattcagg cacaggcgag cggttactgg ctggagcggg
    27241 agcagtggct ggcgggtgag ttttgcgagc agctaccgca ggaactggat tttaaccagc
    27301 ccgcgccgtt gccgcgccag tgggtgaaca atggttttgc cggatggaat ggtcaggccc
    27361 gcatcgagca gccgcaggaa ggttatgcca tcatcatgga aacgacgcca cctgcaccgt
    27421 gttatttcat ctttgtttcc gaccctgcgt ttgataaagg atatgcgttt gatttcttct
    27481 gtctggaacc gatgagccat gcgccggatg atcatcatcg cccggaaggg ggtgatctca
    27541 ttgcgcttgc accaggtgaa tcaacaactt cagagatgtc gttgcgggtt gcgttgctgt
    27601 aatttataaa atgccggata aggcgttcat gccgcatccg gcatctttcc taacgccgat
    27661 cgagagaaat cgcccccggt ccggtaattg ccaacagcag gaatgcgcca gcgatactga
    27721 cattcttcca gaaattaatc atatttggcc caaccgcatc gccggtcata tcctagtaat
    27781 ggtgaccaat caccgccgta cccagcgtgt agaaaataaa cagcaccgcc agcggacggg
    27841 tgaaaaagcc aagcacgatt aatatcgcgg cgggcacttc cataactacc gcaataatcg
    27901 ctgccagcat cggcatcggc gcgcccaacg aggccatata ttggaccgta ccgtcaaagc
    27961 ccatcatttt gggaaaacca aaaataatga aaattaagac cacggcgata cgggcaatta
    28021 ataacaaaac ggggcgggca gctccaaaat caaaataacg tagtgtgttc ataaccaatc
    28081 cctttgcaag attatgtgat ttaaacgtaa tacacactct tgcacctcgc cacgccccag
    28141 gcattgagat attcgctaat tatcctggtt acagtgattt aagcgcgatg ttctcatcta
    28201 tcagcagttt cgcatcaaac gttttgccgc tctggatcca tttgcgaatt gggcgaatct
    28261 cacgcccctg attcagcgtg actgcaccga taagcacgcc gttttgcaga ttaaaccaaa
    28321 tcgccttctg agtttccggg ttgccacgac aaagccagtc atcgccacgc atatcgccaa
    28381 taaactgtaa gttatcactg tactgatcgc tccagaacca cggcggcggc agtagcggta
    28441 gcggtagccc taacattgcg gcagcggcaa tttgcgcctg gttattggcg ttttcccagc
    28501 tttcgcagcg gtgtagtgca ccattatcaa gacgagtgat tgccacatcg ccaccggcaa
    28561 agatcgcggg atcgcaggtg cggcaagcct catcaatgac aatgccattg gcagtatcaa
    28621 ggttggcctc gcgagccagt tgctcgttgg cgctgatacc aataccgtaa atcaccacat
    28681 cagcctgaag cgtttcccca ctttgcagcg tcagttctac tttttcacca tcgaccacat
    28741 gttcaatggc attattgagc agaatgcgca caccagcctg ctggtggcgc tgtaaaagat
    28801 agcgttgcac gggcggtggt gcattacggc ccatgacggt tgccgccagt tcaatcactg
    28861 tcaccttaca tctgcgctgc gtggcgctgg cagccagttc cagaccaata gttccggcac
    28921 cgacaatcac gactgaccgt tcgggctgca gaacttctcg cagtctggcg gcatcaccgg
    28981 catggcgtag ggtaaagcag cgttctccca gtgcatcaag caacggcagc ggtcgagctg
    29041 ccgcgccggt tgctataaaa agctgatccc agtgccagct ttcgccgttg gttaacacta
    29101 actctcgtgt gtcgcgaccc agcgttttga tggttacacc ggaatgcaga tgaacattgt
    29161 tttcctgcca ccagttagcg ggtaacacct gctgtaactg cggggaatct tccagcaaca
    29221 tggatttcga gagtggaggt cgttcataag gaagatgtcg ctcatcggaa aacagatgca
    29281 gctcaccggt gaacccttgc tggcgtagcg aggccgcagc cattgccgcc gcttgcccgc
    29341 caccgacaat aatgatggtt ttttctttca tcgtgcttcc ttaaagatcc agcccagccg
    29401 ctacgtggcg aatgccgcga atcgctaaac ccgcatcagc gttgatcatc acaccgctta
    29461 atgcgcgatt attgcgccgc gatgccaaca tcacatacgg acccgtaaaa tccgccggtt
    29521 gcgggaaaaa ttgcagcggt aaaatggcgg caattttctc cggcgtcaga gactgcatta
    29581 tcgaggtttc actttgcccg agcgcctgtg ggccgcgcag gtcgctggcc ataccacacg
    29641 ggccgacgcc attcacccgc actttcggtg ccagttcata agccagttgg cgaataagtc
    29701 cggttgcggc atgtttactg gcggtgtaca gcgggccacc gccgccagga taccaggcgg
    29761 catttgacag tgtgaaaatc atgctgcctt cactggcgat taacgccgga gcgcaggctt
    29821 ttgcgcccag caggtaaccg agtacgttga cgttaaacag ctcgtggaag ccggtttcga
    29881 gcgtctctgc gggagtatta accagtgagg cattgtgatc ccagatgcct gcattgccga
    29941 taaaacaatc cagcttgccg gaacgagtca ggatctgatc gaccgcgcgt tgataatcgg
    30001 cataacaggt cacgttacct tccaccgcca gaatatgttc gccaaatcgc tgacgcagac
    30061 tggcgacttt tgccgccgac agttccagcg tggcaacctg cgcgccttct tcgataaatc
    30121 gctcgaccag cgccagccct aatcccgatc cgccgccggt aataaaaatg gactcgttat
    30181 gcagatcgct catggctgcg cctccggtaa gtcgatgaaa atgtcaccac cttcaacgtg
    30241 tactggataa gtggtgagcg gatcggtggc gggcaggcat aacgctttcc ccgttttcag
    30301 gcaaaaactg gcggcgtgta gcgggcactc caccgtggcg tcatcttcca gatacccttc
    30361 tgacatcgac gcattaccat ggctgcaacg atcgttaatg gcataaaact cgccgccaac
    30421 gttgaacagg gcgatgacgg gcgaggtatc gatccggaga gcctcaccct ccggcacatc
    30481 cgcaacggga cacgcataaa ttcgattcat cagaacagta cactcaggtt atgggaagtg
    30541 attaccgctt gatccaggac gatatcccgt tccagcaagc gccagttgtc atcttccaga
    30601 cggcgaactt tgtcgaaacg cgttccaaca tagaatgttt catcgcgctc tttttgtgcc
    30661 cgataaagca gataatttac ccgcacagca aatacgtttg ggatgtcggt ttcgcttatc
    30721 tggcagttgc tgattaagtg acgggtgcgt gacggcggct cttctgccca ggccatgccc
    30781 gtttccagac gggcgattcg ccgctccagc tggtctttgg tgtcattaaa aatccaggtt
    30841 gtcggtggct ggacgccttt gcggcggtcg cgtgtttgcg cgttaactgt ggtgcgcatg
    30901 gtgtaacgaa tctcttcgtc gagctgcgcc agccagtcac gaaatttcca gtcgtccagt
    30961 aagctggctt cgtgaaagag aaactggcta atgcggtgat gtaactctag tgaaacttgc
    31021 gcactcattt catcacctcc tgctggtaag cggcggtttt atcgagcact tcctgccagc
    31081 tttcgctact cagaagatcg gcccagcgtt ggtacattcc acgagcggca gtttctgaaa
    31141 agatatagtt agtaatgcca ggaatgccgt cgtcgcggcg cttttcctga ccaagcccca
    31201 tttccagaca cagtttgctg ttgcgggcgc ggtggccttt aagcaatttc tggatttcac
    31261 accagttctc cgagtcatcc tgctcgagaa aaccagcagg accaaaagca cgagtggcgc
    31321 tgttttcaaa agcggcttta acttcatcgg aggcggcttt gtcagtaata cagaacgccc
    31381 acacttcaac ttgatcaggg ccgcgcggat gccagacgcg gagtgtggca gtgccgttta
    31441 gccatgaaag cgtggggaaa atattgttat gacccgccag gcgcagggcg cgaacttcac
    31501 ctaaacgttg ttctgcttcg gcataggttt cgcggtaata gcttgaaact gcgccatcga
    31561 cccagacatt agcatccggt ttttcagtaa agaagaaacc gctaccgtga ccgtcctgac
    31621 caaattgcag cgcatctttg gcggtttccc acaccgggcg ggcggtttgt ccatcaccga
    31681 ggcgcttatc gctgccatca tctttcgccc ctaatacctg aacggcagaa gcatggctga
    31741 acagagcatg atactggtca ctggcgaact gctctgccgg gaatttccag ttacagttga
    31801 tcacccactt ttgtacgccg ccgacaattt cggtgccgcc ttcgcgacga tccagcatgc
    31861 catccagata ccaggcaatg tcacccaggt aatcacgcag gcccggtgcg ctggtatccc
    31921 agttgccaaa aatcagccct ttataactct ccacacaagg aacttcgttt agtccccagt
    31981 gggatttaca caacccttgt gggtaggcgc gaggttccag cggtacatcg atcaactcgc
    32041 cgttaatgcc ataagaccag ccgtgatacg ggcaggtaaa ggcgcgagtg ttgccgcaat
    32101 ctgcataact cacacgcatg gcccggtggc ggcattggtt gagaaacgcc ttgatgctgc
    32161 cgtctttctg acgcactacg acaaccgcat cttcccccat gtaggtgtta aagaaatcac
    32221 caggttttgg gatctggctt tcgtgggcga gaaatagcca gcaacggccg aaaatacgtt
    32281 caagctccag ttggtaaata tctgggtcgg tataaatacg cggagtgacc cgaccatttt
    32341 gggtatcaat cagttggtaa atgttcaaat ctgagggtgt ggtcatattt tttaatcctg
    32401 aaagatcaga tgtattgacc ttctattttt gtgccataag gatgttgctg gttggttgct
    32461 aatatgtgaa atagttaatt tctaccagct gagacgtttt ttcgataaca aggggaaggt
    32521 gatggaacta cggcatttac gctatttcgt cgcagtggcg caggcactga actttacccg
    32581 tgcggcggaa aaactgcata cctcacagcc ttcgttaagc agccagatcc gcgatcttga
    32641 aaactgtgtc ggtgttccgt tactggtgag ggataagcgc aaagtcgcgt tgacggcggc
    32701 gggagaatgt tttctccagg acgcgctggc aatcctcgaa caagcggaaa atgccaaatt
    32761 acgggcgcgg aaaattgttc aggaagacag acaattaacc attagctttg tgccatcggc
    32821 ggaagtgaat ttactgccaa aagtattacc gatgtttcgt ctcagacagc cagacacctt
    32881 gattgagctg gtgagtttaa tcaccacgca acaggaggaa aaaattcgcc gtggtgaact
    32941 cgacgtcggc ttaatgcgcc atcctgttta tagcccggag attgattatc tggagctttt
    33001 tgacgaacca ttagtggttg tgttaccggt tgatcaccct ttagcacatg aaaaagagat
    33061 caccgccgcg caactggatg gcgtgaattt cgtcagtacc gatccggcgt attccggttc
    33121 gcttgcgccg atcgttaaag cgtggtttgc gcaagaaaac agccagccaa atatcgtcca
    33181 ggtggcaacg aatattctgg tgaccatgaa tctggtgggc atggggctgg gcgtcacttt
    33241 gatacccggt tatatgaata attttaatac cggacaggtt gtttttcgtc ccattgccgg
    33301 aaatgtgcct tccattgctt tactgatggc gtggaagaaa ggggagatga agccggcatt
    33361 acgcgatttc atcgccattg tgcaggaacg tttggcaaac gtaacggcat aattacgcat
    33421 tatttttgca acatgcgtcg cggatcgcag ttttttagtg cttgtgaact ggcgttacag
    33481 acatcgggaa gcaggctcga atattcttat ttttcaactt gcaccaacat tcgattaacc
    33541 ccagactaac gcctcctgac gggagggact catggttttg caatccacgc gctggttggc
    33601 gctcggctat ttcacatact tttttagtta cggcattttt ctacctttct ggagcgtctg
    33661 gcttaaaggg attggtttaa cgccagaaac catcggcctg ttattggggg caggtctggt
    33721 tgcccgtttt ctcgggagtt tgctcatcgc gccccgcgtc agcgatcctt cccgcctgat
    33781 ttccgccttg cgcgtgctgg cactgctgac acttctcttt gctgtcgcct tctgggcggg
    33841 ggcgcacgta gcgtggctga tgctggtgat gattggcttt aacctctttt tctcaccgct
    33901 ggtaccgttg accgatgcac tggcgaatac gtggcaaaag cagttcccgc ttgattacgg
    33961 caaagtgcga ctgtggggct cggtggcgtt tgtcattggc tcggcgctga cgggcaaact
    34021 ggtcactatg tttgattatc gggtgatcct cgcgctgttg acgttgggcg tggcatccat
    34081 gctgctcggc tttctcatcc gtccgacgat tcagccacaa ggggaaagcc gccagcagga
    34141 gagcaccggt tggtcagcgt ggttggcgct ggttcgccag aactggcgct ttctggcctg
    34201 cgtttgttta ttgcaggggg cacatgcggc ctattacggt tttagcgcca tttactggca
    34261 ggcagctggc tactcggcct cggcggtggg gtatttgtgg tcgctgggcg tggtggcgga
    34321 agtcattatc tttgcgctga gtaataaact tttccgccgt tgtagtgcac gcgatatgct
    34381 gttgatctcg gcgatttgcg gcgtagtgcg ctggggcatt atgggagcaa ctacggcgtt
    34441 gccgtggttg atagtggtgc aaattctgca ttgcggcacc ttcacggtct gccacctggc
    34501 cgccatgcgt tatattgctg ctcgccaggg tagcgaagtc atccgtttac aggcggttta
    34561 ctctgccgtc gcgatgggcg gcagtatcgc tatcatgacc gttttcgccg gtttcctgta
    34621 tcaatatctg ggccacggcg tgttctgggt aatggcgctg gtggcgcttc cggcaatgtt
    34681 tttgcgcccg aaagttgttc cctcatgctg attcgagcat tttgcggatc tgctcctgtt
    34741 gatgtgttgt cagcgtcagg tccgtataga tcagcggtgg tgaaaagagc ggtaatggca
    34801 tggtataagg cgcaataatc agtgccgcgc cacgcggagc gcctgtctgc aaaaatgcct
    34861 ttaccgacat atgcttaatg ttgagcggca gtaacgttag ttcgcgtaac tgctgctcaa
    34921 tctgcgcttc tcgctcgcta tcattcccgg taagaagaat aatctgtttt tcatgcagat
    34981 cgttttcctg cattagccag gcaccgaaaa tcaccgcgac cagaccactt tcctcatcag
    35041 aaagatggac gccgtattca ctttcaaatc cggccagcgc cgcgcgggtg gtgcgcacca
    35101 ggcgtgggta cagtctggcg aactcttccg gcagggtatt atcaataccg atggcaaaca
    35161 aactgcgatt taacgcctgg gcgaggtggg tataaagctg atcacataac ccctgttcat
    35221 cataaaaacg aacatttccc agctcacgaa aatggtttac cagacgtttg atagactgac
    35281 gcaattgtct gtctcgctga tgcgcatccc gcagtggatc gggaacccgc aacatggaaa
    35341 aaagtagtgc cataaacagt ggctcatcag gtggtacagg ctggagcgcc cgacgctgcc
    35401 agtggcgtcc aatttcctgc gctacctgaa attcaaggca ggattccgcc cagcgacgtt
    35461 ggagcggatt aaactgaggc gtaattccag cgtggtgttg cagcaaacaa tattgcagat
    35521 acagacacag gaaatgaata tcgcgcgttt caaagcgttt ttgcagccgt cgggagcaga
    35581 gattcactaa cgcttgtaga ttggtatcgt cataaaagtt acgcgcaatt ccgcgccgct
    35641 tcagttcact cttcagggcg ggggtgaaat ggctggtaat aaatgatgga cacagacgga
    35701 aaccacgtcg tagccagtga aataaacaca aacgttggtt aagcactgta ccttcaaccc
    35761 ggtagctacc gtcataacca gccgtcagtg tgagttgatg atagcgcagg atctcctgtc
    35821 ctgtttcgct gatatcaaga ctggcaatat catcatccac accattaagc tcgctgaaag
    35881 ttgccgtggt ggcggtcaac cccggctgaa agagcgtcag caagatctgg cagcggcgct
    35941 ggggagccga aaggacagat ggtggagcaa gcgtaggcat catctgtaga tctcccataa
    36001 gcataattga taagaatagc taaagtttgc tcagggaaat gacgaaggga atgctaatca
    36061 tcagaaatgt tggcaagcgt cacagaattt ttctcatctt aaactgttct gaccagtgga
    36121 ttagcatgtc ttaaggtggt tttgtgaatg attatcgtgc tagcgatcat gggttagttc
    36181 tgcggattca acgcgctaag gataaagtcc accatctgtt cgcgataaac atcgccgtgg
    36241 cgatcggaaa aagcatcaat gtgttcgcca tccgggatta ggatcaaccg ttttggctct
    36301 tttgccaggc tatacaactt ttcgctgtgc tgccatggga taacgtgatc agctttaccg
    36361 tgaatgagta aaagcgggat cgggctgacg ctggcgatat aattttcgcc gctgtaactc
    36421 tcatcaagta agtagccact gccggggatc atctggttgg cgatggttgc ataagaggca
    36481 aatgtggagt cgaggatcac cgcacgtatg ccttcacgat caccctgacc aataacagca
    36541 agaatattcg ccccgccaat actctgcccg aacagcacca gccgttgtgg gtttacatca
    36601 ctgcgatggc gcaccacatt gatggcgctt tgcgtatcgt ccagcaatcc ggcctgggac
    36661 ggcgtgcctt ttgatttacc aaacccgcga taatcaaaca taaaaacgtt gaaattacgc
    36721 tcgggtaacc aactgaccag cggccagtgg gcggacatat ttccggcatt gccgtgagca
    36781 tgaatgatgg ttgcgatggc gttgtcagca gggcccgtcg aagaaggaat aaaccagcct
    36841 tgcagacgag taccgtcctt agccgtaaat tcgacggatt ccgccgacca ggggtcggga
    36901 ccgtaaattt tatcgtcagg ataatagaag aagttgatgg caacgcgcgg cactaaataa
    36961 acgcagaagg caacaacaaa gagaataaac agaattttgg gaacgcgttt gttcactggc
    37021 agtgccataa cctttccttg cgacttcttt atcatccatt aatcggggaa agatggtggg
    37081 agagtgacga aagaaagtaa agcggtgagg aagtatttca gaatagcgcc tgaaaggcga
    37141 gggcgggtga gtgacatcac ccgcctgagt cattaacgct tcagagcgtc gcttaactcg
    37201 tcacgcatgt tcgccagcat ggctttcaca acacgtgggt taccagcaac gatgttaccg
    37261 gtcagcatat agttatgacc accggtgaag tcgctgacga tgccgcccgc ttcacgaacc
    37321 agcagctcgc ctgccgcgaa atcccacgga cgcagaccga tttcaaagaa accgtcaaca
    37381 cgacccgcag cgacgtaagc cagatccagc gccgcagaac cggtacgacg gaagtctgca
    37441 cattcgttga acagtttgcc gacgatgttg atgtaggtag tggcgtactg ttttgctttg
    37501 aacgggaagc cggtcgccag aatggtaccg tcgagatcgc gagcggtgct accgcgcaga
    37561 cggtagccgt tcagctgtgc gccctgaccg cgagtggcgg tgaacagttc gttacgcata
    37621 ggatcgtata ccacagcaac ttcggtgcgg cctttgatac gaacggcgat agataccgcg
    37681 aagtgcggca gacgtttgat aaagttggta gtaccatcca gtggatcgat aacccattga
    37741 acatcctgat cagtaccttc aagttcaccg ctttcttcgg tgatgatggt gtgctgtggg
    37801 taagatttac gaatcgtgtc gataatcacc gcttcggcag ctttatctac gttggtcacg
    37861 aaatcgttac tgcctttctg gctcgcttct acagcgtccg gggtttcata gtttttggca
    37921 attaaattac ccgccttgcg cgctgcgcgc acggcgatgt tcagcatcgg atgcatcggt
    37981 ctctctcact ggatgttaaa gaacgggaaa acggcgcaga gtatagcagc gagatcggca
    38041 tctgtcttcg ttttatgata agatgcgtga ataatcttta gatgaagaaa gacaatgctg
    38101 caaaatattc gaattgtgct ggtggagacg tcacacaccg gcaatatggg ttctgttgcc
    38161 cgtgccatga aaacaatggg attaaccaat ctgtggctgg ttaatccact ggtgaaaccc
    38221 gactcccagg cgattgccct ggcagcaggg gccagcgatg tgattggtaa tgctcacatc
    38281 gtcgatacgc tcgacgaagc gttagccggt tgtagcctgg tggtgggcac cagcgcacgc
    38341 tcccgcacgc tgccgtggcc gatgctcgac ccgcgcgaat gcggtctgaa aagcgtcgct
    38401 gaagcggcaa ataccccggt ggcgctggtg tttggtcgtg agcgcgtcgg cttgaccaat
    38461 gaagagttgc agaaatgcca ttatcatgtc gcgattgcgg ctaacccgga atacagctcg
    38521 ctgaacctgg cgatggcggt tcaggttatt gcctatgaag tgcgcatggc ctggctggca
    38581 actcaggaaa acggcgagca ggtcgagcat gaagagacgc cgtatccgct ggtcgatgat
    38641 ctggagcgtt tttatggtca tctggaacaa acgctgctgg caaccggttt tatccgtgaa
    38701 aaccatccgg ggcaggtgat gaataaattg cgccgtctgt ttacccgtgc gcgcccggaa
    38761 agccaggaat tgaatatcct gcgcgggatt ctggcttcta ttgagcagca gaataaaggt
    38821 aacaaggccg aataacagta gttgcctgat gcgacgctta acgcgtctta tcaggcctac
    38881 aatgtacaga accgtaggtc ggataaggtg ttcacaccgc atccgacaac aggtacaaac
    38941 gccacgataa aaaaatggca ctgaaggtta aatacccgag taaatcagtc aagtaaatag
    39001 ttgaccaatt tactcgggaa tgtcagactt gaccctgcta tgcaataccc ccacttttac
    39061 aataaaaaac cccgggcagg ggcgagtttg aggtgaagta agacatgaga ctgacatcta
    39121 aagggcgcta tgccgtgacc gcaatgcttg acgttgcgct caactctgaa gcgggcccgg
    39181 taccgttggc tgatatttcc gaacgtcagg gaatttccct ttcttatctg gaacaactgt
    39241 tttcccgtct gcgtaaaaat ggtctggttt ccagcgtacg tggaccaggc ggtggttatc
    39301 tgttaggcaa agatgccagc agcatcgccg ttggcgaagt gattagcgcc gttgacgaat
    39361 ctgtagatgc cacccgttgt cagggtaaag gcggctgcca gggcggcgat aaatgcctga
    39421 cccacgcgct gtggcgtgat ttgagcgacc gtctcaccgg ttttctcaac aacattactt
    39481 taggcgaact ggttaataac caggaagtgc tggatgtgtc tggtcgtcag catactcacg
    39541 acgcgccacg cacccgcaca caagacgcga tcgacgttaa gttacgcgct taataaaaag
    39601 aattcagaat caggccggag tgctaaatac tccgtaaaca cggtcgtaca tccagccggt
    39661 agcctgattc cttgcattga gtgatgtacg gagtttatag agcaatgaaa ttaccgattt
    39721 atctcgacta ctccgcaacc acgccggtgg acccgcgtgt tgccgagaaa atgatgcagt
    39781 tcatgacgat ggacggaacc tttggtaacc cggcctctcg ttctcaccgt ttcggctggc
    39841 aggctgaaga agcggtagat atcgcccgta atcagattgc cgatctggtc ggcgctgatc
    39901 cgcgtgaaat cgtctttacc tctggtgcaa ccgaatctga caacctggcg atcaaaggtg
    39961 cagccaactt ttatcagaaa aaaggcaagc acatcatcac cagcaaaacc gaacacaaag
    40021 cggtactgga tacctgccgt cagctggagc gcgaaggttt tgaagtcacc tacctggcac
    40081 cgcagcgtaa cggcattatc gacctgaaag aacttgaagc agcgatgcgt gacgacacca
    40141 tccttgtttc catcatgcac gtaaataacg aaatcggcgt ggtgcaggat atcgcggcta
    40201 tcggcgaaat gtgccgtgct cgtggcatta tctatcacgt tgatgcaacc cagagcgtgg
    40261 gtaaactgcc tatcgacctg agccagttga aagttgacct gatgtctttc tccggtcaca
    40321 aaatctatgg cccgaaaggt atcggtgcgc tgtatgtacg tcgtaaaccg cgcgtacgca
    40381 tcgaagcgca aatgcacggc ggcggtcacg agcgcggtat gcgttccggc actctgcctg
    40441 ttcaccagat cgtcggaatg ggcgaggcct atcgcatcgc aaaagaagag atggcgaccg
    40501 agatggaacg tctgcgcggc ctgcgtaacc gtctgtggaa cggcatcaaa gatatcgaag
    40561 aagtttacct gaacggtgac ctggaacacg gtgcgccgaa cattctcaac gtcagcttca
    40621 actacgttga aggtgagtcg ctgattatgg cgctgaaaga cctcgcagtt tcttcaggtt
    40681 ccgcctgtac gtcagcaagc ctcgaaccgt cctacgtgct gcgcgcgctg gggctgaacg
    40741 acgagctggc acatagctct atccgtttct ctttaggtcg ttttactact gaagaagaga
    40801 tcgactacac catcgagtta gttcgtaaat ccatcggtcg tctgcgtgac ctttctccgc
    40861 tgtgggaaat gtacaagcag ggcgtggatc tgaacagcat cgaatgggct catcattaat
    40921 cggtatcgga atcaggagaa tttataatgg cttacagcga aaaagttatc gaccattacg
    40981 agaatccgcg taacgtgggt tcctttgaca acaacgacga gaacgtcggc agcggcatgg
    41041 tgggggcacc ggcctgtggc gacgtgatga agttgcagat taaagtcaac gatgaaggta
    41101 tcattgaaga cgcgcgtttt aaaacttacg gctgcggttc tgctatcgct tccagctccc
    41161 tggtcaccga atgggtgaaa gggaagtctc tcgacgaagc gcaggcgatc aaaaacaccg
    41221 atattgctga agaacttgaa ctgccgccgg tgaaaattca ctgttctatt ctggcagaag
    41281 acgcgatcaa agccgccatt gcggactata aaagcaaacg tgaagcaaaa taagagttga
    41341 ggtttggtta tgtcgattac actgagcgac agtgcagcag cgcgagtaaa tacctttctg
    41401 gctaaccgcg gcaaagggtt tggcctgcgt ctgggcgtga gaacctccgg atgttcaggt
    41461 atggcttatg tactggaatt tgttgacgaa ccgacgccgg aagacatcgt gtttgaagac
    41521 aaaggcgtga aagtcgtggt cgatggcaaa agcctgcaat ttctggacgg tacgcagctg
    41581 gacttcgtaa aagaaggcct gaatgaaggg tttaaattca ccaacccgaa cgttaaagat
    41641 gagtgtggtt gcggcgaaag cttccacgtt tgatgcgcat accgataacc ccaccgtggt
    41701 cgcctgcgcg tggggtttgt tttacctgat tcgccgttat cgcggcggat cgcagccctg
    41761 agaatgttat ggattacttc accctctttg gcttgcctgc ccgttatcaa ctcgataccc
    41821 aggcgctgag cctgcgtttt caggatctac aacgtcagta tcatcctgat aaattcgcca
    41881 gcggaagcca ggcggaacaa ctcgccgccg tacagcaatc tgcaaccatt aaccaggcct
    41941 ggcaaacgct gcgtcatccg ttaatgcgcg cggaatattt gctttcttta cacggttttg
    42001 atctcgccag cgagcagcat actgtgcgcg acaccgcgtt cctgatggaa cagttggagc
    42061 tgcgcgaaga gctggacgag atcgaacagg cgaaagatga agcgcggctg gaaagcttta
    42121 tcaaacgtgt gaaaaagatg tttgataccc gccatcagtt gatggttgaa cagttagaca
    42181 acgaggcgtg ggacgcggcg gcggataccg tgcgtaagct gcgttttctc gataaactgc
    42241 ggagcagtgc cgaacaactc gaagaaaaac tgctcgattt ttaatttctg gaagctaaac
    42301 atggccttat tacaaattag tgaacctggt ttgagtgctg cgccgcatca gcgtcgtctg
    42361 gcggctggta ttgacctggg cacaaccaac tcgctggtgg cgacagtgcg cagcggtcag
    42421 gccgaaacgt tagccgacca tgaaggccgt cacctgctgc catctgttgt tcactatcaa
    42481 cagcaagggc attcggtggg ttatgacgcg cgtactaacg cagcgcttga taccgccaac
    42541 accattagtt ctgttaaacg cctgatgggg cgctcgctgg ctgatatcca gcaacgctat
    42601 ccgcatctgc cttatcaatt ccaggccagc gaaaacggcc tgccgatgat tgaaacggcg
    42661 gcggggctgc tgaacccggt gcgcgtttct gcggacatcc tcaaagcact ggcggcgcgg
    42721 gcaactgaag ccctggcagg cgagctggat ggtgtagtta tcaccgttcc ggcgtacttt
    42781 gacgatgccc agcgtcaggg caccaaagac gcggcgcgtc tggcggggtt gcatgttctg
    42841 cgcttactta acgaaccgac cgctgcggct atcgcctacg ggctggattc cggtcaggaa
    42901 ggcgtgatcg ctgtttatga cctcggtggc gggacgtttg atatttccat tctgcgctta
    42961 agtcgcggcg tgtttgaagt gctggcaacc ggcggtgatt ccgcgctcgg cggcgatgat
    43021 ttcgaccatc tgctggcgga ttacattcgc gagcaggcgg gcattcctga tcgtagcgat
    43081 aaccgcgttc agcgtgaact gctggatgcc gccattgcag ccaaaatcgc gctgagcgat
    43141 gcggactccg tgaccgttaa cgttgcgggc tggcagggcg aaatcagccg tgaacaattc
    43201 aatgaactga tcgcgccact ggtaaaacga accttactgg cttgtcgtcg cgcgctgaaa
    43261 gacgcgggtg tagaagctga tgaagtgctg gaagtggtga tggtgggcgg ttctactcgc
    43321 gtgccgctgg tgcgtgaacg ggtaggcgaa tttttcggtc gtccacctct gacttccatc
    43381 gacccggata aagtcgtcgc tattggcgcg gcgattcagg cggatattct ggtgggtaac
    43441 aagccagaca gcgaaatgct gctgcttgat gtgatcccac tgtcgctggg cctcgaaacg
    43501 atgggcggcc tggtggagaa agtgattccg cgtaatacca ctattccggt ggcccgcgct
    43561 caggatttca ccacctttaa agatggtcag acggcgatgt ctatccatgt aatgcagggt
    43621 gagcgcgaac tggtgcagga ctgccgctca ctggcgcgtt ttgcgctgcg tggtattccg
    43681 gcgctaccgg ctggtggtgc gcatattcgc gtgacgttcc aggtcgatgc cgacggtctt
    43741 ttgagcgtga cggcgatgga gaaatccacc ggcgttgagg cgtctattca ggtcaaaccg
    43801 tcttacggtc tgaccgatag cgaaatcgct tcgatgatca aagactcaat gagctatgcc
    43861 gagcaggacg taaaagcccg aatgctggca gaacaaaaag tagaagcggc gcgtgtgctg
    43921 gaaagtctgc acggcgcgct ggctgctgat gccgcgctgt taagcgccgc agaacgtcag
    43981 gtcattgacg atgctgccgc tcacctgagt gaagtggcgc agggcgatga cgttgacgcc
    44041 atcgaacaag cgattaaaaa cgtagacaaa caaacccagg atttcgccgc tcgccgcatg
    44101 gaccagtcgg ttcgtcgtgc gctgaaaggc cattccgtgg acgaggttta atatgccaaa
    44161 gattgttatt ttgcctcatc aggatctctg ccctgatggc gctgttctgg aagctaatag
    44221 cggtgaaacc attctcgacg cagctctgcg taacggtatc gagattgaac acgcctgtga
    44281 aaaatcctgt gcttgcacca cctgccactg catcgttcgt gaaggttttg actcgctgcc
    44341 ggaaagctca gagcaggaag acgacatgct ggacaaagcc tggggactgg agccggaaag
    44401 ccgtttaagc tgccaggcgc gcgtcaccga cgaagattta gtggtcgaaa tcccgcgtta
    44461 cactatcaac catgcgcgtg agcattaaca gaggttagta tgggacttaa atggaccgat
    44521 agccgcgaaa ttggcgaagc actgtacgat gcgtatcccg atcttgatcc gaaaacggtt
    44581 cgattcaccg atatgcatca gtggatttgc gatctggaag atttcgacga cgacccgcag
    44641 gcatccaacg agaaaatcct cgaagcgatt ttgttagtct ggctggacga ggccgaataa
    44701 tttccgcgtc atgcttcacg ccgcagatgc gttggctgcg ctcgttcacc ccagtcacat
    44761 agttatctat gctcctgggg cttcactcac ttgccgcctt cctgcaacgc gaatcattta
    44821 gcggaaaaat cctggggctg ccaactggcg gcccttttac aaagaaggat aactaaaatg
    44881 acagaagcga tgaagattac cctctctacc caacctgccg acgcgcgctg gggagaaaaa
    44941 gcaacttaca gcattaataa tgacggcatt accctgcatt tgaacggggc agacgatctg
    45001 gggctgatcc agcgtgcggc gcgcaagatt gacggtctgg gcatcaagca tgttcagtta
    45061 agcggtgaag gctgggatgc ggatcgctgc tgggcattct ggcaaggtta caaagccccg
    45121 aaaggcacgc gtaaagtgga gtggccggat ctggacgatg cccagcgcca ggaactggat
    45181 aaccgcctga tgatcatcga ctgggtgcgt gacaccatca acgcaccggc agaagaattg
    45241 ggaccatcgc aactggcaca gcgtgctgtt gatctgatca gcaacgtcgc gggcgatcgt
    45301 gtgacttatc ggatcaccaa aggcgaagat ctgcgtgagc aaggttatat ggggctgcac
    45361 accgtcggac gcggttcaga acgttctccg gtattgctgg cgctggatta caacccaact
    45421 ggcgataaag aagcgccagt gtacgcgtgc ctggtaggta aaggtatcac ttttgactcc
    45481 ggcggctaca gcatcaaaca gactgcgttt atggactcga tgaagtcgga catgggcggc
    45541 gcggcaacgg ttaccggggc gctggcattt gccattacgc gcggactgaa caagcgcgtg
    45601 aagctgttcc tctgctgtgc ggataacctg attagcggca atgcgttcaa gctgggcgat
    45661 atcatcacct atcgcaacgg taaaaaagtt gaagtgatga acactgatgc cgaagggcgt
    45721 ctggtgcttg ccgatggtct gattgatgcc agtgcgcaga aaccggaact gatcattgat
    45781 gcggcgaccc tcaccggggc ggcgaaaact gcgctgggta atgattatca cgcgctgttc
    45841 agttttgacg atgcgcttgc cggtcgtttg ctggcgagtg cctcacaaga gaacgaacca
    45901 ttctggcgtc tgccgctggc ggaattccac cgcagccagc tgccgtctaa ctttgccgaa
    45961 ctgaacaata ccggaagcgc ggcgtatccg gcaggcgcga gcacggcggc gggcttcctg
    46021 tcgcactttg ttgagaacta tcagcaaggc tggctgcata tcgactgctc ggcgacttac
    46081 cgtaaagcgc cggttgaaca gtggtctgcg ggtgctacgg gacttggtgt gcgcacgatt
    46141 gctaatctgt taacggcgta aactaatatg ccggatgcgg cgtaaatgcc ttatccggcc
    46201 tacaaattct gcaaattcaa caaattgcga atcccttgta ggcctgataa gcgtagcgca
    46261 tcaggcattt gcgccccgaa cgttgaatga attgtggttc ttatgtccga aacaaaaaac
    46321 gaacttgaag acctgctgga aaaagcagca accgaaccgg cgcaccgccc ggcctttttc
    46381 cgtactctac tggaatccac cgtctgggtg cctggtacgg cggcgcaggg cgaggctgtg
    46441 gttgaagata gtgcgcttga tttacagcac tgggaaaaag aagacggcac cagcgtcatt
    46501 ccttttttca cctcgttaga agcgcttcaa caggcggttg aagacgaaca ggcatttgtc
    46561 gtaatgcccg ttcgcacatt gtttgagatg acccttggcg aaacgctctt ccttaatgcc
    46621 aaactgccga ccggtaaaga atttatgccg cgtgaaatca gtttgttgat tggtggagag
    46681 ggaaatccgc tgagcagcca ggaaatcctg gaaggcggtg aatcgctgat attatcggaa
    46741 gtcgcagagc cgccagcaca aatgattgat tcactcacca ccttatttaa aaccattaag
    46801 ccggtgaagc gtgcttttat ttgttcaatt aaagagaacg aagaggcaca gcctaattta
    46861 cttattggca ttgaagccga tggtgatatc gaagaaatta ttcaggcgac gggaagtgta
    46921 gcgaccgata cattacctgg cgatgaacca atcgatattt gtcaggtgaa aaaaggggaa
    46981 aaaggaatta gccactttat taccgaacat attgcgccat tctatgaacg tcgctggggt
    47041 ggttttttgc gtgactttaa acagaaccgg ataatctaaa atatgccgcc ctaaagggcg
    47101 gcattcgggc ttacttgctg ctctgaaggt tgttaaccac cagtaaattg tcgccggaga
    47161 gactccggtt attatttact tgggaaaaca gcgcaccaga aacaataagt acgatacaga
    47221 agcaccgtat cttcattgtg cggtccatgc gaagaccgca tcacgacagc accactggcg
    47281 atattgccgc gatagcaagc gctgagacgc gcttgctcta acggtcgcgg aacatccttt
    47341 ccttaagcca gcgcccgctt gcgagacggc ggaaagggcc gcagtggata atacactaac
    47401 agaacaataa taactctctt ttgcttgaca aaaagagagt tactggcgag tattgtctcc
    47461 gctgagacgc gcttgcatta ctacggtaat acaacctgct ggaaaggccg cgaaccggac
    47521 cagcaacaaa taaccgcctg attttggcgg ttttttgttt tttaaaggaa agtgaattta
    47581 catgtttaag taatatcttt taccggttag tatttttaat tttgagcagg atttgtttat
    47641 atttgtctga attcggacta ataagccagg ttaatttatt accgaacacg gcggaaaggg
    47701 ccggtgtcga taatacgcta aataaacaat aattactctc ttttgcttga caaaaagaga
    47761 gttactggtg agtattgttt tgctgtgaag cacctgcgtt gctcatgtaa cacaagtcaa
    47821 cctgctggaa aggccgcgaa ccagaccagc aataaaaaac cgccaaattc ggcggttttt
    47881 tattgcctgt aaaatactta tttcactggc tcaaccggta aatctgcccg cgcgccccat
    47941 tcactccatg cgccgtcgta cagtttcacg tttggcacat ccagcgtcgc gagtgctaac
    48001 aaaaccacgg ctgccgttac accagagccg cagctgacga taattggttt gtcgtagctg
    48061 acgccgcgac caaaaaatat cgcatccagt tcatcggtcg tttttagttc gccttcgcgc
    48121 accagttccg tccacggaac attcagtgct ccgggaatat gtccgcgacg taaacctggg
    48181 cgaggttcat caacttctgc gttaaaacgt gcagccgggc gggcatcaat aatttgcgcc
    48241 gtattttcat ggcttgccaa taatacatcg gttactttca ccacggcttc aggattaaac
    48301 gcggcgttaa actctccttc cggcagctct actgcacctt cttctaacag cagatcatcg
    48361 cgctgccagc ctgcaagtcc accccccaga atcgacactt tctctacacc aaaggtgcgc
    48421 agcatccacc atgctcgtgg ggctgagaaa agattacctt cgtcatagac aatcaggtgc
    48481 ttatcctggt taacgcctaa ttcacgcatc gccacggcga acgtttccgg gcgcggcagc
    48541 atgtgcggaa gcggggaagt gtgatcagaa agcgcttcga tatcaaaaaa cactgcgccg
    48601 ggaatatgtc cattcagata ctcctgagca acgttacgat cttcctgtcc aggcgacgcc
    48661 atgcgggcat caataatctg aatttccggg tcatcaatat gttcggcgag ccagtcggct
    48721 cctacaaacc atgtcgtgga cataggcatc tccatttttg ccggggttag gctaaattgt
    48781 cggatgttta gtgaaaagcg acaagcgaaa gaggctgatt tggctgtctg agccacaatt
    48841 ctcactaaaa ttcggattgt atgggcgtga tactgaatta cataacgtaa attctcacgc
    48901 ataataatta ttcgacgttg ctaacgggcc attgtggcag ggatgaaaaa tgaaaaagtt
    48961 acgcgtagcc gcctgcatgc taatgctggc gctggcaggg tgcgacaaca acgataacgc
    49021 gccaacagcg gtgaaaaaag atgcgccttc tgaagttact aaagcggcct cttcagaaaa
    49081 cgcgagttca gcaaaactct ccgtgccgga gagacaaaaa ctggcccaac agagtgccgg
    49141 taaggtgctg acattgctgg atctctctga agtccaactt gatggtgcag ccacgctggt
    49201 gctgacgttc tccatccctc tcgacccgga tcaggatttc tcacgcgtta ttcatgtcgt
    49261 cgataaaaaa agcggcaaag tggatggtgc ctgggagctg tcagataatc ttaaagagtt
    49321 acgtttacgc cacctcgaac cgaaacgtga tttgatcgtt actattggca aggaggtcaa
    49381 agcactcaac aacgcaacct tcagtaaaga ttacgaaaaa actataacta cccgcgacat
    49441 ccaacccagc gtcggttttg ccagccgtgg ttcgctgctg cctggcaaag tcgttgaagg
    49501 gctgccggta atggcgctca acgttaataa tgtcgatgtt aacttcttcc gcgttaagcc
    49561 agaatctctg ccagcattca ttagccaatg ggaataccgc aattcgctgg cgaactggca
    49621 gtcagacaaa ctgctgcaga tggcggatct ggtctacacc ggacggtttg atctcaatcc
    49681 tgcgcgtaac acccgtgaaa aattattgct gccgctgggc gatatcaaac cgcttcagca
    49741 ggcgggcgtg tatctggctg tgatgaatca ggctggacgt tacgattaca gtaatcccgc
    49801 gacgctgttt acgttaagtg atatcggcgt ttcagctcac cgttatcaca atcgtctgga
    49861 tatctttacc caaagtctgg aaaacggcgc ggcccagcaa ggaattgaag tctctttatt
    49921 aaatgagaaa gggcagactc tgactcaggc aaccagtgac gctcaggggc atgtgcagct
    49981 ggaaaatgat aaaaacgcgg cattactgtt ggcgcgtaaa gacggtcaga caacgctact
    50041 cgatttaaaa cttccggcgc tggacttagc agaatttaac attgctggcg cgccaggcta
    50101 tagcaaacag tttttcatgt ttggcccacg cgatctttat cgcccaggtg aaacggtaat
    50161 cctcaatggt ttgctgcgtg atgcagacgg taaagcgttg cccaatcaac ccatcaagtt
    50221 agacgtgatt aaacccgatg ggcaggtact caggagcgtc gttagtcagc cggagaatgg
    50281 cctctaccac tttacctggc cactcgatag caatgcggca accggtatgt ggcatattcg
    50341 cgctaacacg ggcgataacc agtatcggat gtgggatttc cacgtcgaag attttatgcc
    50401 agagcgcatg gcgctgaatc tgaccggtga gaaaaccccg ctaacgccga aagatgaagt
    50461 gaaattctcc gtggtggggt actacctgta tggtgcacct gctaatggta atactttgca
    50521 agggcaactt ttcctgcgcc cactgcgtga agctgtgtca gccttacctg gttttgaatt
    50581 cggcgatata gctgccgaaa atctttcccg cacgctggat gaagttcagt tgacgctgga
    50641 tgataaaggg cgcggcgaag tttctacaga aagccagtgg aaggaaacgc attccccatt
    50701 acaggttatt ttccagggta gtttgctgga atcgggcggt cgcccggtga cgcgccgcgc
    50761 tgagcaggct atctggcctg ccgatgcatt gccggggatc cgtccgcagt tcgcctcgaa
    50821 atcggtttac gattatcgta ctgacagcac ggtgaaacag cccattgttg atgaaggcag
    50881 taacgccgct tttgacatcg tttatagcga tgcgcaaggc gtgaaaaaag ccgtgtcggg
    50941 cttgcaggtg cgcctgattc gcgaacgccg cgattactac tggaactggt cagaagatga
    51001 aggctggcag tcacagtttg atcaaaaaga tctgatcgaa aatgaacaaa ctctggatct
    51061 gaaagcggac gaaaccggca aggtcagttt tccggtagag tggggcgctt atcgtctgga
    51121 agtcaaagcg ccgaatgaag cggtcagtag tgttcgtttc tgggctggct atagctggca
    51181 ggacaacagc gacggtagcg gcgcagtgcg acccgaccgt gtcacgctga aactggataa
    51241 agccagttat cgccctggcg acaccattaa gttgcatatc gccgcgccaa cggcgggtaa
    51301 aggttatgcg atggtcgagt ccagtgaagg gccgctgtgg tggcaagaga ttgatgttcc
    51361 ggctcaaggg ctggatctga cgattccggt cgataaaacc tggaatcgtc atgatctgta
    51421 tttaagtacg ctggtggtac gtcctggcga taaatctcgc tccgcgacgc caaaacgcgc
    51481 ggttggtgtg ttgcatctgc cgcttggcga tgaaaaccgt cgcctcgatc tggcgctgga
    51541 aacaccagca aaaatgcgtc ccaatcaacc attaaccgtg aaaattaaag ccagcactaa
    51601 aaatggcgag aagcctaaac aggtgaatgt gctggtgtct gccgttgata gtggtgtgct
    51661 gaatattact gactacgtca cgccagatcc gtggcaggcg ttctttggtc agaaacgcta
    51721 tggcgcagac atttacgata tttacggtca ggttattgaa ggtcaggggc gtctggcagc
    51781 tctgcgtttc ggtggcgatg gtgatgagct gaaacgtggt ggtaaaccgc cggtcaatca
    51841 cgtcaatatt gtcgcgcagc aggcgctgcc ggtaacgctc aacgaacagg gcgaaggctc
    51901 ggttacactg ccgattggcg attttaacgg tgaattgcgc gtcatggcgc aagcctggac
    51961 ggcagatgat ttcggtagca acgaaagcaa agtgatagtt gccgcaccgg tgattgctga
    52021 actgaacatg ccgcgcttta tggcgagtgg cgatacctcg cgtctgacgc tggatatcac
    52081 taatcttacc gataaaccgc aaaaactgaa cgttgccctg accgccagtg gtttgcttga
    52141 actggtcagc gattcacccg cagccgttga attagcgcca ggtgtgcgta ctacgctgtt
    52201 tatcccggtg cgagcattgc cgggttatgg cgatggagaa attcaggcca ccattagcgg
    52261 gttagcgtta ccgggtgaaa ccgttgccga tcagcataag cagtggaaaa tcggcgtccg
    52321 tccggcgttc ccggcacaaa cggttaatta cggtacggcg ttacagcctg gtgagacatg
    52381 ggcgattccg gcggatggat tgcaaaactt ctcgcctgtt acgctggaag ggcaattgtt
    52441 gttgagcggc aaaccaccgc tgaacattgc acgttatatc aaagagttaa aagcgtatcc
    52501 gtacggctgt cttgagcaaa ccgccagcgg cctgttcccg tcactttata ccaacgcagc
    52561 ccaactgcag gcgttgggca tcaaaggcga cagtgatgag aaacgccgtg catcggtcga
    52621 tatcggcatt tcccgtttgc tgcaaatgca acgtgataac ggcggctttg cgctgtggga
    52681 taaaaacggt gacgaagagt actggctgac ggcttacgtg atggatttcc tggtccgcgc
    52741 aggcgaacag ggttacagcg tgccgacaga cgccattaac cggggtaatg agcgtctgct
    52801 gcgctattta caagatccgg gcatgatgtc gatcccgtac gcggataatc tcaaagccag
    52861 taaattcgcc gttcagtctt acgctgcgct ggtgctggcc cgtcagcaaa aagcaccact
    52921 gggtgcgctg cgtgaaatct gggagcatcg tgcagatgcc gcttctggtt taccgctgct
    52981 gcaacttggc gttgcgctga aaaccatggg tgatgcaacg cgtggtgaag aagcgattgt
    53041 gctggcgctg aaaacgccga gaaatagtga tgagcggata tggctgggtg attacggtag
    53101 tccactgcgc gacaacgcgt taatgctcta cttgctggaa gaaaataaac tgctacccga
    53161 tgagcagaac actttgctga acacgctttc gcagcaggca tttggtgaac gctggctatc
    53221 gacgcaggaa agtaacgcgt tgttcctggc tgcccgtacg attcaggatt taccgggtaa
    53281 atggcaggcg caaacctctt tctcagctga gccgctgaca ggcgagaaaa cgctaaacag
    53341 caatctgaat agcgatcaac ttgccacctt gcaggtgaga aacagtggcg atcagccgtt
    53401 atggctgcgt gtggatgcca gcggttatcc gcaatccgca cctttaccgg cgaacaatgt
    53461 gctgcaaatc gagcgtcata ttcttggtac tgatggtaag agcaaatcgc tggactcgtt
    53521 acgtagcggc gatctggtgc tggtctggtt gcaggtaaaa gccagtaaca gcgtgccgga
    53581 tgcgttagtc gtggatctgc tgcctgcggg tctggaactg gaaaatcaga atctggcgaa
    53641 cggtagcgcc agcctggagc aaagtggtgg cgaagtgcaa aacttactga accagatgca
    53701 gcaggcgagt attaagcaca ttgagttccg tgacgatcgc tttgtggcgg cggttgccgt
    53761 tgatgaatac caaccggtaa cgctggtgta tctggcgcgg gcggtgacgc cgggaacgta
    53821 tcaggtaccg caaccgatgg tggaatcaat gtatgttccc caatggcggg cgaccggcgc
    53881 ggctgaagat ctgctgattg tccgaccgta aatgcctcgc ttgttaacca aacgcggctg
    53941 ctggataacg ctggcagctg cgccatttct cctttttctt gcagcgtggg gagcagataa
    54001 actctggcct ctaccgctgc atgaagtcaa tcccgcacga gtggtcgtgg cgcaggatgg
    54061 tacgccgcta tggcgcttcg ccgatgctga cggcatctgg cgttatccgg taacaatcga
    54121 agatgtttct ccacgttacc ttgaagcgct gatcaattat gaagatcgct ggttctggaa
    54181 gcatccgggg gtgaatccat tctcggtggc gcgcgcagca tggcaagatc tcacttcggg
    54241 acgggttatt tccggtggca gcacgctcac tatgcaggtt gctcgtctgc ttgatcctca
    54301 ccccaaaaca tttggcggca aaattcgcca gctctggcgc gcgttgcaac tggaatggca
    54361 tctgtctaag cgtgaaattc tgaccttgta tcttaaccgc gctccgtttg gcggtacgtt
    54421 gcaggggatc ggtgcggcaa gttgggctta tctcggaaag tcgcctgcga atttaagcta
    54481 ttccgaggcg gcaatgctgg cggttttgcc gcaagcgccc agccgtcttc gcccggatcg
    54541 ttggccggag cgtgccgaag ccgcgcgtaa taaagtgctc gaacggatgg ccgtgcaagg
    54601 tgtgtggtcc cgtgagcagg taaaagagtc aagggaagaa cccatctggc tggcaccccg
    54661 acaaatgccg caactggcac cgctgttttc gcgcatgatg ctcggtaaaa gcaaaagcga
    54721 caaaatcgtt actacgctgg atgccggtct tcaacgacgt ctggaagaac tggcgcaaaa
    54781 ctggaaaggg cggttgccac cgcgcagctc actggcgatg atcgtggttg atcataccga
    54841 tatgcgtgtt cgcggctggg tgggatcggt tgatctcaac gatgattcac gctttggtca
    54901 tgttgatatg gtcaatgcga tccgatcgcc aggatcggtg ctcaaaccgt ttgtttatgg
    54961 tctggcgctg gatgaaggct tgatccaccc ggcatcactg ctgcaagacg tcccccggcg
    55021 caccggtgat tatcgaccag gtaactttga tagcggtttt catggcccga tcagcatgag
    55081 cgaggcgctg gtgcgctcgc tgaacttacc tgctgtgcag gtgctggaag cctatggacc
    55141 gaaacggttt gcggcaaagt tacgcaatgt tggattgccg ttatatttgc ccaacggtgc
    55201 tgcgccgaat ctttcactca ttctcggcgg cgctggtgca aaactggaag atatggcggc
    55261 agcgtatacc gcgtttgctc gccacggcaa ggcaggcaaa ttgcgcttac agcctgacga
    55321 tccgctgctt gaacggcctt taatgtcgtc gggggcggcg tggatcattc gccggattat
    55381 ggctgatgaa gcgaaaccct tgccggatag tgccttgccg cgcgtcgccc cactggcatg
    55441 gaaaacgggc accagctatg gctatcgtga cgcctgggcg attggggtta acgctcgcta
    55501 tgtcattggg atctggactg gcagaccgga cggcacgccc gttgttggtc agtttggctt
    55561 tgccagtgcc gtaccattgt tgaatcaggt caataatatc ttactgtcgc gcagtgcgaa
    55621 tctgccggaa gacccgcgcc cgaactcagt cactcgtggc gttatctgct ggccgggcgg
    55681 acagtctttg ccggaaggtg acggtaactg tcgccgccgc ctggcaacct ggctgctgga
    55741 cgggagtcag ccgccaactc tattactgcc ggatcaggaa ggcattaatg gcattcgttt
    55801 ccccatctgg ctggatgaaa atggcaaacg tgttgccgct gattgcccgc aagcgcgaca
    55861 agaaatgata aatgtctggc cgctaccgct ggaaccctgg ctgcccgcat cagaacgtcg
    55921 cgctgtgcgc ttaccaccgg cctcgacaat ttgcccgtca tacggtcacg atgcccagct
    55981 ccctctgcag ctgacaggcg ttcgcgatgg cgcgattatt aaacgtttac cgggcgcagc
    56041 ggaagcgact ttgccgttgc aatcaagtgg aggggcaggt gaacgctggt ggtttctgaa
    56101 tggcgaaccg ttaactgaac gcgggcgcaa cgtgaccctg catttgacgg ataaaggtga
    56161 ttatcaattg ctggtgatgg atgatgtggg gcaaatcgcg acagtgaaat ttgtcatgca
    56221 atagtctgtt ttgtccctga ttgttgctaa aactcatttt attttaaaaa aatgttacct
    56281 tcatcaatag tcaacggccc tgttgctcat tataatccgc gccatctcgt acgctggtac
    56341 agacaacaac agaacaattt acagaggtaa aaatggctat tgaacgtact ttttccatca
    56401 tcaaaccgaa cgcggtagca aaaaacgtca ttggtaatat ctttgcgcgc tttgaagctg
    56461 cagggttcaa aattgtcggc accaaaatgc tgcacctgac cgttgaacag gcacgtggct
    56521 tttatgctga acacgatgga aaaccgttct ttgatggtct ggttgaattc atgacctctg
    56581 gcccgatcgt ggtttccgtg ctggaaggtg aaaacgccgt tcagcgtcac cgcgatctgc
    56641 tgggcgcgac caatccggca aacgcactgg ctggtactct gcgcgctgat tacgctgaca
    56701 gcctgaccga aaacggtacc cacggttctg attccgtcga atctgccgct cgcgaaatcg
    56761 cttatttctt tggcgaaggc gaagtgtgcc cgcgcacccg ttaataattt cgtaaatgcc
    56821 gcgtgcaaac gtggcatccg tgcgccagaa tttgtacaat gcagcgcccc cggacgagca
    56881 gccgctcacc ggggcgtttc ttttttcaat cctccagggg ccataacgtg taataacgag
    56941 gccggaatag catatgtctg aacaattagt cacacctgaa aacgtcacca cgaaagatgg
    57001 aaaaatcaac ctgctggatc tcaaccgtca gcagatgcgg gagtttttta aagatttagg
    57061 tgaaaaaccc ttccgcgccg atcaggtgat gaagtggatg tatcactatt gctgcgacaa
    57121 ctttgatgag atgaccgaca tcaacaaagt gttgcgcggc aaactgaaag aggtggcgga
    57181 aatccgcgca ccggaagtgg ttgaagaaca gcgttcatcc gacggcacca ttaaatgggc
    57241 gatcgccgtt ggcgatcagc gcgtcgaaac ggtgtatatc ccggaagacg accgtgccac
    57301 gctctgcgtc tcttcgcagg tggggtgtgc gctggagtgt aaattctgtt ccaccgccca
    57361 gcagggcttt aaccgcaacc tgcgggtatc ggaaattatt ggccaggtgt ggcgtgcggc
    57421 gaaaatcgtc ggcgcagcaa aagtcaccgg tcagcgccca atcactaacg tagtgatgat
    57481 gggcatgggc gagccgctgc tcaacctgaa caacgtcgtt ccggcgatgg aaatcatgct
    57541 tgatgatttc ggttttggcc tgtctaaacg tcgcgtcacg ctttctactt ccggtgtagt
    57601 tccggcgctg gataaactgg gcgatatgat cgacgttgca ctggcaattt ccctgcacgc
    57661 gccgaacgac gaaattcgtg acgaaattgt gccgatcaac aaaaagtaca atatcgaaac
    57721 gttccttgct gcggtgcgcc gttatctgga gaaatccaac gccaatcagg gccgtgtcac
    57781 tattgagtat gtgatgcttg accacgttaa cgacggcact gaacacgcgc accaactggc
    57841 ggaactgctg aaagatacgc cgtgtaagat caacctgatc ccgtggaacc ccttcccggg
    57901 cgcgccgtat ggacgcagct cgaacagccg tatcgaccgt ttctcaaaag tgctgatgag
    57961 ctacggtttc accactattg tgcgtaaaac ccgtggtgat gatatcgatg ctgcctgtgg
    58021 tcagttggcg ggcgatgtta tcgaccgtac gaaacgtacc ctgcgtaaac ggatgcaggg
    58081 tgaagccatc gacattaaag cggtctgata gccattacgc cacggttact ttatgtaccg
    58141 tggcgtaatc ttttatgaat gaagtattaa gttgcaattg tctggtcaat attaacggtg
    58201 cgtttttgct gactttaagg cagtatgtaa cgatgcaaca gtaagttagc cttagtgaat
    58261 gtgggctttg tcacgagcac acagacggtc ttatactgta tgataacggt taacttaacg
    58321 gatgtttcgc ggtgtgggtg agcatgatgg ttcaccggca tctcaattct catttaaacg
    58381 tacctgcagc gaatgaatac tgaagccacg cacgaccaaa atgaagcact tactaccggc
    58441 gctcgcctgc gtaatgctcg cgaacaacta ggacttagtc agcaggccgt tgccgagcga
    58501 ctttgcctga aggtttccac ggtacgcgac attgaagaag ataaggcacc cgccgatctt
    58561 gcttcaacat tcctgcgcgg atatatccgc tcttatgcgc gtctggtaca tattccagaa
    58621 gaagaactgc tgccagggct ggaaaagcag gctccactac gggctgcaaa agttgcgcct
    58681 atgcagagtt tttccctcgg taaacgccgc aaaaaacgtg acggctggct gatgaccttc
    58741 acctggctgg tgttgtttgt ggttatcggc ctgagcggtg cctggtggtg gcaagaccac
    58801 aaagctcagc aggaagagat caccactatg gccgatcaat cttcggcgga actgagcagt
    58861 aatagcgagc aggggcagag tgttccgtta aatacgtcga caactacaga cccggctaca
    58921 acgtccacgc cgccagcgtc tgtggatact accgcaacca acacgcaaac acctgccgta
    58981 actgcgccag caccagctgt tgatccgcaa cagaatgcgg ttgtttcgcc ttcgcaggca
    59041 aatgttgata ccgccgcgac cccggcacca acggcaacaa caacgccaga tggcgctgcg
    59101 ccgttgccaa ccgatcaggc aggcgtgact acgccggcgg ctgatccgaa tgcgctggtg
    59161 atgaacttta ctgccgattg ctggctggag gttactgatg ctaccggtaa aaaattgttt
    59221 agcggtatgc agcgtaaaga cggtaatttg aacttaaccg gccaggcacc atacaaactg
    59281 aaaattggtg cgccagccgc agtacagatc cagtatcaag ggaaacctgt cgatctgagt
    59341 cgttttatca gaactaacca ggttgcgcgt ctgaccctca atgccgaaca atcaccggcg
    59401 cagtaacaga cgggtaacgc gggagatttt tcatgcataa ccaggctcca attcaacgta
    59461 gaaaatcaac acgtatttac gttgggaatg tgccgattgg cgatggtgct cccatcgccg
    59521 tacagtccat gaccaatacg cgtacgacag acgtcgaagc aacggtcaat caaatcaagg
    59581 cgctggaacg cgttggcgct gatatcgtcc gtgtctccgt accgacgatg gacgcggcag
    59641 aagcgttcaa actcatcaaa cagcaggtta acgtgccgct ggtggctgac atccacttcg
    59701 actatcgcat tgcactgaaa gtagcggaat acggcgtcga ttgtctgcgt attaaccctg
    59761 gcaatatcgg taatgaagag cgtattcgca tggtggttga ctgtgcgcgc gataaaaaca
    59821 ttccgatccg tattggcgtt aacgccggat cgctggaaaa agatctgcaa gaaaagtatg
    59881 gcgaaccgac gccgcaggcg ttgctggaat ccgccatgcg ccatgttgat catctcgatc
    59941 gcctgaactt cgatcagttc aaagtcagcg tgaaagcgtc tgacgtcttc ctcgctgttg
    60001 agtcttatcg tttgctggca aaacagatcg atcagccgct gcatctgggg atcaccgaag
    60061 ccggtggtgc acgcagcggg gcagtaaaat ccgccattgg tttaggtctg ctgctgtctg
    60121 aaggcatcgg cgacacgctg cgcgtatcac tggcggccga tccggtcgaa gagatcaaag
    60181 tcggtttcga tattttgaaa tcgctgcgta tccgttcgcg cgggatcaac ttcatcgcct
    60241 gcccgacctg ttcgcgtcag gaatttgatg ttatcggtac ggttaacgcg ctggagcaac
    60301 gcctggaaga tatcatcact ccgatggacg tttcgattat cggctgcgtg gtgaatggcc
    60361 caggtgaggc gctggtttct acactcggcg tcaccggcgg caacaagaaa agcggcctct
    60421 atgaagatgg cgtgcgcaaa gaccgtctgg acaacaacga tatgatcgac cagctggaag
    60481 cacgcattcg tgcgaaagcc agtcagctgg acgaagcgcg tcgaattgac gttcagcagg
    60541 ttgaaaaata ataacgtgat gggaagcgcc tcgcttcccg tgtatgattg aacccgcata
    60601 gctcccgaaa cattgaggga agcgttgagg gttcattttt atattcagaa agagaataaa
    60661 cgtggcaaaa aacattcaag ccattcgcgg catgaacgat tacctgcctg gcgaaacggc
    60721 catctggcag cgcattgaag gcacactgaa aaacgtgctc ggcagctacg gttacagtga
    60781 aatccgcttg ccgattgtag agcagacccc gctattcaaa cgtgcgattg gtgaagtcac
    60841 cgacgtggtt gaaaaagaga tgtacacctt tgaggatcgc aatggcgaca gcctgactct
    60901 gcgccctgaa gggacggcgg gctgtgtacg cgccggcatc gagcatggtc ttctgtacaa
    60961 tcaggaacag cgtctgtggt atatcgggcc gatgttccgt cacgagcgtc cgcagaaagg
    61021 gcgttatcgt cagttccatc agttgggctg cgaagttttc ggtctgcaag gtccggatat
    61081 cgacgctgaa ctgattatgc tcaccgcccg ctggtggcgc gcgctgggta tttccgaaca
    61141 cgtaactctt gagctgaatt ctatcggttc gctggaagca cgcgccaatt accgcgatgc
    61201 gctggtggca ttccttgagc agcataaaga aaagctggac gaagactgca aacgccgcat
    61261 gtacactaac ccgctgcgcg tgctggattc aaaaaatccg gaagtgcagg cgcttctcaa
    61321 cgacgctccg gcattaggtg attatctgga cgaggaatct cgtgagcatt ttgccggtct
    61381 gtgcaaactg cttgagagcg cggggatcgc ttacaccgta aaccagcgtc tggtgcgtgg
    61441 tctggattac tataaccgta ccgttttcga gtgggtgact aacagtctcg gctcccaggg
    61501 caccgtgtgt gcaggcggtc gttatgacgg tcttgtggaa caactgggcg gtcgtgcaac
    61561 accggctgtc ggttttgcga tgggcctcga acgtcttgta ttgttagtac aggccgttaa
    61621 tccggaattt aaagccgatc ctgttgtcga tatatacctg gtggcttcag gtgctgatac
    61681 acaatctgcg gctatggcat tagctgagcg tctgcgtgat gaattaccgg gcgtgaaatt
    61741 gatgaccaac cacggcggcg gcaactttaa gaaacagttt gcccgtgctg ataaatgggg
    61801 tgcccgcgtt gctgtggtgc tgggtgagtc tgaagtggct aacggcacag cagtagtgaa
    61861 ggatttgcgc tctggtgagc aaacggcagt tgcgcaggat agcgtagccg cgcacttgcg
    61921 cacgttactg ggttaaggaa ggagaaggac agcgtggaaa tttacgagaa cgaaaacgac
    61981 caggtagaag cggttaaacg cttttttgct gaaaatggca aagcactggc tgttggggtg
    62041 attttgggcg ttggcgcact gattggctgg cgctactgga acagccatca ggttgattct
    62101 gcacgctccg cttctcttgc ctatcaaaat gcggttaccg cagtgagcga aggcaaaccg
    62161 gatagcatcc cggcggcgga aaaatttgct gctgaaaata aaaatactta tggtgcgctg
    62221 gcttctttgg aacttgcgca gcaatttgtt gacaaaaatg aactagagaa agctgccgcc
    62281 cagttacaac aggggctggc agacacgagc gatgaaaatc tcaaagccgt gataaatctg
    62341 cgtcttgctc gcgttcaggt acagctcaag caggctgatg ccgcgctgaa aacccttgat
    62401 accatcaaag gtgaagggtg ggctgccatt gttgccgacc tgcgtggtga agcattgctg
    62461 agcaaaggtg ataagcaagg tgcgcgtagt gcatgggaag caggcgtgaa aagcgatgtt
    62521 actccggcac tgagcgaaat gatgcagatg aaaattaata atttgtccat ctgagaggga
    62581 cccgatgcaa ttgcgtaaat tactgctgcc aggactgctt tccgttaccc ttttaagcgg
    62641 ctgttcgctg tttaacagcg aagaagatgt ggtaaagatg tccccattgc caaccgttga
    62701 aaaccagttt acgccgacca cggcgtggag tacttccgtt ggtagcggca ttggcaactt
    62761 ctattccaat cttcatccgg cactggcgga caacgttgtc tatgcagcgg accgcgctgg
    62821 tttggtaaaa gcgctgaatg cggatgatgg caaagaaatc tggtctgtca gcctggccga
    62881 gaaagatggc tggttctcta aagagcctgc attactttct ggcggtgtga ccgtgtctgg
    62941 tgggcatgtc tacattggca gcgaaaaggc gcaggtttac gcgctgaata ccagcgatgg
    63001 tactgtggca tggcaaacta aagtcgcggg tgaagcactt tcgcgcccgg tggtcagcga
    63061 cggtctggtg ttaatccaca ccagtaacgg tcagttacaa gcgctgaacg aacctgacgg
    63121 cgctgtcaaa tggacagtta accttgatat gccttcgctc tctttgcgtg gcgagtctgc
    63181 gccggcaacg gcttttggtg cggccgtcgt ggggggcgat aatggtcgcg tcagcgcagt
    63241 gctgatggaa cagggccaga tgatttggca gcagcgtatt tcccaggcga ccggttctac
    63301 cgaaattgac cgtctgagcg atgttgacac gactcccgtc gttgttaacg gcgttgtttt
    63361 cgcgctggcc tataatggta acctgacggc gcttgatctg cgcagtggtc agattatgtg
    63421 gaaacgcgaa ctgggttcgg tgaatgattt catcgtcgac ggcaatcgca tctatctggt
    63481 cgatcaaaat gaccgggtga tggcgttgac cattgatggc ggcgttacgc tgtgggcaca
    63541 aagcgatctg ctgcatcgcc tgctgacttc tccggtgctg tataatggca acctggtggt
    63601 cggtgacagt gaaggttatc tgcactggat taacgtcgaa gatggtcgtt tcgttgccca
    63661 gcaaaaagtt gatagttccg gtttccagac tgaaccggtt gccgctgacg gcaaactgct
    63721 gatccaggca aaagacggaa ccgtgtactc tattacacgt taatcgtctc tgtcgttcac
    63781 tttgaaaacg gctcctggac aggggccgtt ttcctgtttt taacaacgac gcgaatatag
    63841 cgtgcgttgt ctgatgattt ataaaaatga ggctttaaac atggtacctg tggtcgcgct
    63901 tgtcgggcgc cctaacgtag gaaaatccac gttatttaac cgtctaactc gcacccgaga
    63961 tgcgctggtt gcggatttcc cgggtctgac tcgtgaccgt aagtacggtc gtgcggaaat
    64021 tgaaggccgt gagtttatct gtattgatac cggcgggatt gatggcacag aagacggtgt
    64081 agaaacccgc atggcggaac agtcgctgct ggcgattgaa gaagcggacg tcgtactgtt
    64141 tatggtggat gcgcgcgcgg gcctgatgcc ggcagatgaa gcgattgcca aacatctgcg
    64201 ctcccgtgaa aaaccgacct tcctggtggc aaacaaaact gacggtctgg atcccgatca
    64261 ggcagtggtt gatttctact cgcttggttt aggtgaaatc tacccgatcg ccgcgtctca
    64321 cggtcgtggc gtattaagtc tgctggagca tgtgctgctg ccgtggatgg aagatctcgc
    64381 accgcaagag gaagtcgacg aagacgctga atactgggcg caatttgaag cggaagagaa
    64441 cggcgaagaa gaagaggaag acgacttcga cccgcaaagt ctgccgatca aactggcgat
    64501 tgtgggtcgt ccgaacgtag gtaagtctac actcactaac cgtattcttg gtgaagagcg
    64561 cgttgttgtt tatgacatgc ctggcacgac gcgtgacagt atctacattc caatggaacg
    64621 cgatggacgt gagtatgtgc tcattgacac cgctggcgta cgtaaacgcg gcaaaatcac
    64681 cgatgctgta gagaaattct ccgtaatcaa aacgttgcag gccattgaag atgccaacgt
    64741 ggtgatgtta gtgattgatg cgcgcgaagg tatttccgat caggatctct cgctgctggg
    64801 ctttattctc aatagtgggc gttcacttgt cattgtggtg aataagtggg atggcctgag
    64861 ccaggaagtg aaagagcagg tgaaagaaac gctggacttc cgtctgggct ttatcgattt
    64921 tgctcgtgtg cactttatct ctgccttgca cggcagtggt gttggtaact tgtttgaatc
    64981 agtacgtgaa gcgtatgaca gctccacccg tcgtgtgggg acctctatgc tgacgcgcat
    65041 catgacgatg gctgttgaag atcaccaacc gccgctggta cgcggtcgtc gtgtgaagct
    65101 gaaatatgcc cacgctggtg gttataaccc gccgattgtg gtgattcacg gtaatcaggt
    65161 gaaagacctg cctgattcct acaagcgcta cttgatgaac tacttccgca aatcgctgga
    65221 cgtaatggga tcgccgattc gtattcagtt caaagaaggg gaaaacccgt atgcgaacaa
    65281 gcgtaacacc ctgacgccaa cccagatgcg taaacgtaag cgtctgatga agcacatcaa
    65341 gaaaaataaa taattatccg taagtatttt atctgccatt ccctctatga atgtagaggg
    65401 atggctaccg gaggaattca tatggaactg cattgtccac aatgtcagca tgtgcttgat
    65461 caggataacg gccatgcgcg ttgcccatcc tgcggggaaa ttattgaaat gaaagctctt
    65521 tgtccagact gccatcaacc gttgcaggtg ttaaaagcct gcggtgcagt agattacttc
    65581 tgtcagcacg ggcatggctt gatatcgaaa aaacgcgttg aattcgtgct ggcttaatgc
    65641 acctttttac gcgatttttt taccggctgg atgtttttta cttcactttc tatccagccg
    65701 tcttccagac gtgtggttag catttcaccc gctttaactt gcttcacttt tttcagtaca
    65761 ttgccgtcag tagcagtagt aacgctgtat ccacgcgcca gcgttgacag tgggcttacg
    65821 gcttcgaggt gcgttactgc attaccgaaa cgttcacgcg tggcgctaag ctgtacgcgc
    65881 agggtttctg ctaaacgata ttccagttgc tgaatgcgcg tttgcgcgcg atgaatcttc
    65941 ggctgtggat tttgctgatt cagccgctgt gttaaccgct gctgctgttg cccggtacgc
    66001 ttaagttgat tttccagcgc aaagctcatc cgcttttgca ggcgctcaag catggtttgc
    66061 tggcgtgcca gccggagctg cggatgctgt tgctgtaatc ggtgatggat ctgcgtaaag
    66121 cgacgcgtgc ggttggcgag ataataatcc atcgccatct ccagccgttg acgggtcgat
    66181 tgcacctggc gcagtaactc ttgctgatta cggctcacta cttcagcggc ggcagacggc
    66241 gttggcgcac gcagatcggc aacaaaatcg gcaatggtca catccgtctc atgcccgacg
    66301 gcgctgacga ccggaatgcg gctggcaaaa atcgcccgcg ctacgcgttc gtcgttaaaa
    66361 ctccataaat cttccagcga accgccgccg cgcccaacga tcaacacgtc gcactcattg
    66421 cgctgattcg ccagttcaat ggcgcgaaca gtttgccccg gcgcgtcatc gccctgaacg
    66481 gcggtggggt agatgatcac cggtagagaa ggatcgcgac gttttaacac atgcaaaata
    66541 tcatgtagcg cagcaccggt ttttgaggtg atcacaccaa cgcaatgcgc aggggaggga
    66601 agtggttttt tgtattgcag atcgaacaat ccttcagcct gcaacttcgc tttgagctgt
    66661 tcgtacttct gttgcagcag cccttcaccg gccggctgca tactctcaac gattatctgg
    66721 tagtcgccgc gcggctcgta gagcgtaata ttggcgcgaa ctaaaacttg ttgcccatgc
    66781 tgtggacgga aggtcacccg acggttgctg ttgcggaaca tcgcgcagcg tacctgggcg
    66841 gtgtcgtctt tgagtgtaaa gtaccagtga ccggaagccg gttgtgtgaa attagagatt
    66901 tcgccgctga tccaaacctg tcccatctca tgctcaagca gcagacgaac cgtttgattc
    66961 aggcgactaa cggtaaaaat tgcaggggat tgagaaggta acatgtgagc gagatcaaat
    67021 tcaaaatcag caggttattc agtcgatagt aacccgccct tcggggatag caagcatttt
    67081 ttgcaaaaag gggtagatgc aatcggttac gctctgtata atgccgcggc aatatttatt
    67141 aaccactctg gtcgagatat tgcccatgct acgtatcgct aaagaagctc tgacgtttga
    67201 cgacgttctc ctcgttcctg ctcattctac cgttctgccg aatactgctg acctcagcac
    67261 ccagctgacg aaaactattc gtctgaatat ccctatgctt tccgcagcaa tggataccgt
    67321 aacggaagcg cgcctggcta ttgctctggc tcaggaaggc ggtatcggct ttatccacaa
    67381 aaacatgtcc attgaacgcc aggcagaaga agttcgccgt gtgaaaaaac acgaatctgg
    67441 tgtggtgact gatccgcaga ctgttctgcc aaccacgacg ctgcgcgaag tgaaagaact
    67501 gaccgagcgt aacggttttg cgggctatcc ggtcgttacc gaagaaaacg aactggtggg
    67561 tattatcacc ggtcgtgacg tgcgttttgt taccgacctg aaccagccgg ttagcgttta
    67621 catgacgccg aaagagcgtc tggtcaccgt gcgtgaaggt gaagcccgtg aagtggtgct
    67681 ggcaaaaatg cacgaaaaac gcgttgaaaa agcgctggtg gttgatgacg aattccacct
    67741 gatcggcatg atcaccgtga aagacttcca gaaagcggaa cgtaaaccga acgcctgtaa
    67801 agacgagcaa ggccgtctgc gtgttggtgc tgcagttggc gcaggtgcgg gtaacgaaga
    67861 gcgtgttgac gcgctggttg ccgctggcgt tgacgttctg ctgatcgact cctcccacgg
    67921 tcactcagaa ggagttttgc agcgtatccg tgaaacccgt gctaaatatc cggatctgca
    67981 aatcatcggc ggcaacgtgg caacagctgc aggtgcacgc gctttggcag aagctggttg
    68041 cagcgcggtt aaagtcggta tcggccctgg ttctatctgt acgactcgta tcgttactgg
    68101 cgtaggtgtt ccgcagatca ctgccgttgc tgacgcagtt gaagccctgg aaggcaccgg
    68161 tattccggtt atcgcagatg gtggtattcg cttctccggc gacatcgcca aagctatcgc
    68221 agctggcgca agcgcggtga tggtaggttc catgctggcg ggtactgaag aatctccggg
    68281 tgaaatcgaa ctctaccagg gccgttctta caaatcttac cgtggtatgg gttccctggg
    68341 cgcgatgtcc aaaggttcct ctgaccgtta tttccagagc gataacgctg ccgacaaact
    68401 ggtgccggaa ggtatcgaag gtcgcgtagc ttataaaggt cgcctgaaag agatcattca
    68461 ccagcagatg ggcggcctgc gctcctgtat gggtctgacc ggctgtggta ctatcgacga
    68521 actgcgtact aaagcggagt ttgtacgtat cagcggtgcg ggcattcagg aaagccacgt
    68581 tcacgacgtg accattacta aagagtcccc gaactaccgt ctgggctcct gattctcttc
    68641 gcccgacttc atgtcgggcg atttatatta tctgtttcac ttgcctcgga ataagcgtca
    68701 atgacggaaa acattcataa gcatcgcatc ctcattctgg acttcggttc tcagtacact
    68761 caactggttg cgcgccgcgt gcgtgagctg ggtgtttact gcgaactgtg ggcgtgggat
    68821 gtgacagaag cacaaattcg tgacttcaat ccaagcggca ttattctttc cggcggcccg
    68881 gaaagcacca ccgaagaaaa cagcccgcgt gcgccgcagt atgtctttga agcaggcgta
    68941 ccggtattcg gcgtttgcta tggcatgcag accatggcaa tgcagttggg cggtcacgtt
    69001 gaagcctcta acgaacgtga atttggctac gcgcaggttg aagtcgtaaa cgacagcgca
    69061 ctggttcgcg gtatcgaaga tgcgctgacc gcagacggta aaccgctgct cgatgtctgg
    69121 atgagccacg gcgataaagt taccgctatc ccgtccgact tcgtcaccgt agccagcacc
    69181 gaaagctgcc cgtttgccat tatggctaac gaagaaaaac gcttctatgg cgtacagttc
    69241 cacccggaag tgactcacac ccgccagggt atgcgcatgc tggagcgttt tgtgcgtgat
    69301 atctgccagt gtgaagccct gtggacgcca gcgaaaatta tcgacgatgc tgtagctcgc
    69361 atccgcgagc aggtaggcga cgataaagtc atcctcggcc tctctggtgg tgtggattcc
    69421 tccgtaaccg caatgctgct gcaccgcgct atcggtaaaa acctgacttg cgtattcgtc
    69481 gacaacggcc tgctgcgtct caacgaagca gagcaggttc tggatatgtt tggcgatcac
    69541 tttggtctta acattgttca cgtaccggca gaagatcgct tcctgtcagc gctggctggc
    69601 gaaaacgatc cggaagcaaa acgtaaaatc atcgggcgcg ttttcgttga agtattcgat
    69661 gaagaagcgc tgaaactgga agacgtgaag tggctggcgc agggcaccat ctaccctgac
    69721 gttatcgaat ctgcggcttc tgcaaccggt aaagcacacg tcatcaaatc tcaccacaac
    69781 gtgggcggcc tgccgaaaga gatgaagatg ggcctggttg aaccgctgaa agagctgttc
    69841 aaagacgaag tgcgtaagat tggtctggag ctgggcctgc cgtacgacat gctgtaccgt
    69901 cacccgttcc cgggaccagg ccttggcgtt cgtgtgctgg gtgaagtgaa gaaagagtac
    69961 tgtgacctgc tgcgccgtgc tgacgccatc ttcattgaag aactgcgtaa agcggacctg
    70021 tacgacaaag tcagccaggc gttcactgtg ttcctgccgg tacgttccgt tggcgtaatg
    70081 ggcgatggtc gtaagtatga ctgggttgtc tctctgcgtg ctgtcgaaac catcgacttt
    70141 atgaccgcac actgggcgca tctgccgtac gatttcctcg gtcgcgtttc caaccgcatt
    70201 atcaatgaag tgaacggtat ttcccgcgtg gtgtatgaca tcagcggcaa gccgccagct
    70261 accattgagt gggaatgatt ttaatccctg cactatgaat gaacaaaacc ctctgttact
    70321 acagagggtt ttttatcttc aagaatcata ggcttgaagt tactaacatc gattaattaa
    70381 accagctgtc cgatttgttc tcttctgctt tgcccacgct tttcatcaga tcgcgaccgc
    70441 cttcagtcat atttctgttg gcgtcagctt cagattgcac cacatcggtt tgcgcagctt
    70501 tgtgcttcag ttcctgatcg ataaattcgt tttctcgctt aacgcgggct tcttcttttg
    70561 ccagcgccag tttttgtttc tgaatctcta agctgcgtag ctcatcttca taactttgat
    70621 cgcgtttttt gtccgcagag gcttcggcgt ccagtttatc ctgacgagct ttcttatttg
    70681 ctgctgccgt tgccgctctt ttgttagcgg cggcctgggc atttgcgcga cgttgcttct
    70741 cttgctggat ttccctgttg cgctccgcga cccattcgtc atgctgcttt tgctcttcat
    70801 ttttaccttg ctgttccgct tctgcgacag ccgagagttg atcctgcaat gatgaggcga
    70861 tagccggata gcttaaggag gccaagatgg cgcaaagaaa aactttcttc atgactcctc
    70921 ctgattatta gctcttttca ggacatttag tatttggctg aatacgcgtt tcgttatacg
    70981 tcgtggtaat aacaacggct aaacctgtcg taaactggca ctctttaccc acctgggtgg
    71041 aggtatacac tttggtgcct tccttatacg ttaaagaaac accttccact aaggttttat
    71101 cattcaccat agaacccgct gccgcgccta cagctccgcc gccaactgcc cctgccgtcg
    71161 ttccggaatt gctgccagaa ccgacgttgt ggccgataac accgccagcg actgcgccaa
    71221 taagcgcgcc gaaggcttgt gcgttccgtt tattttggga gttgtctacg gcaacttttg
    71281 cgggaagaat ggaaataata ttaacggttt tagtttcttg tttggtattc agttgatcgg
    71341 tttgataaac atcggcggca tgatcgtcag catttgactg gcatcctgcc agagtgaatg
    71401 acgctaacat tgctacaggc agaagacatt ttttaaattt catcactatt ccttgttata
    71461 cacattacga aaaataagac atttaagatc atcaaaagag gaaagtaaat gtattgcgta
    71521 taaagggata gattaaattt attaaaattc acgccgggaa taatttataa aaatatatca
    71581 ttacaacata tatattaatt ttatatttat ttcgcagcca aacaggataa acatcagtca
    71641 ggacaaagac gtaaaattta agatgaaaga atatctgccg ctttgataat cccaaagagc
    71701 aaaagcatcc gacagcgaag tgccgttagg ttctgtgaaa gtggagaagg taaccgctaa
    71761 cgttgtaccg gtgattcgac ggagagtgtg gattgctgag cttctttttt gctctgatgg
    71821 tgctgccagg caccgacgga cgagtagata aaacggccaa agaagaagat aaagctgatg
    71881 agcagtacga tacgggtcat gcgactgtta aatcggtgtc gttttcgcat actggttgcc
    71941 tgactcacaa aaggttcctt gaagtatgtc ccacgctgtg gacggtactt acattaaggc
    72001 acaacaggac aaaatggtca attcttcgtt atgtaaaaaa gcgtcagtgg atacatattt
    72061 taatgttatg gaagttaatt taattattta caatgatgat gtaataatga tgaattaaca
    72121 tgataaacgt aataattcat taatcagggt tattttgttt gatatatatc aattggaact
    72181 ttcatatgac acttagaatc aatgctctct atagtgatga ataatcatca ttcgaagtca
    72241 ggtgggatgc ctgtctgaat acacctcctt caggatgtgg gggattctgc tgagcatcta
    72301 tgaaactgaa tgcaacttat ataaaaatac gtgataaatg gtgggggctt ccgctgttcc
    72361 tgccttcttt aatcttgccc attttcgccc acattaatac tttcgcgcat atttcttccg
    72421 gtgaggtttt tctcttttat ctgcctttgg cactgatgat cagcatgatg atgtttttca
    72481 gctgggcggc attgccaggg atcaccttag ggatttttgt ccgcaaatat gcagagctgg
    72541 gtttttacga aacgctctca ttaacggcta attttattat cattatcatt ctctgttggg
    72601 gcggttacag ggtctttact ccccggcgta acaacgtttc acatggtgat acccgtttaa
    72661 tttcccagcg tatattctgg cagatagtgt ttcctgcaac gctgtttctg atacttttcc
    72721 agtttgctgc atttgtagga ttactggcga gcagagaaaa tctggtcggt gtcatgcctt
    72781 ttaacctcgg gactttaatc aattatcagg ccttactggt gggtaatctg atcggtgtcc
    72841 cgctgtgcta cttcatcatt cgggtagtgc gaaatccatt ttatttacgt agctattatt
    72901 cgcaattaaa acagcaggtt gatgccaaag tcaccaaaaa agagttcgcg ctctggctac
    72961 tggcattagg tgctttattg ttgctgttat gcatgccgtt aaatgaaaaa agcacaattt
    73021 ttagcaccaa ttataccttg tcattattgt tgcccctgat gatgtgggga gcaatgcgct
    73081 atggttataa gctgatttcg ctgctctggg cggtcgtgtt gatgatcagc atccacagct
    73141 atcaaaatta cattcccatt tatcctggct ataccacgca gctgaccata acctcctcca
    73201 gttatctggt attctctttt attgtcaatt atatggctgt actggcaact cgtcagcgag
    73261 cggtagtcag acgcattcag cggcttgcgt atgtggaccc ggtggttcat ctgccaaatg
    73321 ttcgcgccct gaatcgcgcg ttgcgtgatg ccccctggtc tgcgctttgt tatttacgca
    73381 tccctggcat ggaaatgctg gttaagaact atggcatcat gctgcggatt caatacaagc
    73441 aaaaactttc tcactggctg tcacccttgc tggaaccggg tgaagatgtt tatcagcttt
    73501 cgggtaacga tctcgcgctg cggctgaata cagaatcgca ccaggagcgc attaccgcac
    73561 tggatagcca tctcaagcaa tttcgtttct tttgggatgg catgccgatg caaccgcaga
    73621 ttggcgtcag ttactgctat gtgcgctcgc cagtgaatca tatctacctg ctgctgggag
    73681 agctaaatac ggtcgccgaa ctttccatcg tgaccaacgc cccggaaaat atgcagcgtc
    73741 gcggggcaat gtatttgcaa cgcgaattga aagataaagt cgcgatgatg aatcgactac
    73801 agcaggcgct ggaacacaac cattttttcc tgatggccca gccgattacc ggtatgcgtg
    73861 gtgatgttta ccatgaaatt cttctgcgca tgaaaggtga gaatgatgaa ctgatcggcc
    73921 ccgatagctt cttgccggtc gcgcacgaat ttggtttatc gtcgagtatc gacatgtggg
    73981 tcattgagca tacgctgcaa tttatggctg aaaacagagc gaagatgccc gctcaccgtt
    74041 ttgctattaa tctgtctcca acctcggtat gtcaggctcg ttttcctgtt gaagtcagtc
    74101 agttgctggc taaatatcag attgaagcgt ggcaacttat ttttgaagtc accgaaagta
    74161 atgctctgac caatgttaag caggcgcaaa tcaccttgca gcatcttcag gaattaggct
    74221 gccagattgc gattgatgat ttcggcaccg gctacgccag ctatgcacgg cttaaaaatg
    74281 tgaatgccga tctgcttaaa attgacggca gttttatccg caatattgtg tcaaatagtc
    74341 tggattatca gatagtggca tcgatttgcc acctggcgcg aatgaagaaa atgcgggtag
    74401 tggcagagta cgttgaaaac gaagagatcc gcgaggcggt gctctctttg gggatcgatt
    74461 atatgcaggg ttatcttatt ggtaagccgc agccgttaat tgatacgttg aatgaaatcg
    74521 aacccattcg cgaaagtgcc tgaataatgc gggccgacat ttctcgtcgg cccgcaaagc
    74581 attaagcggc gatttcaggt gtactttctt cttcaatttt caaccgccag ccagccacgc
    74641 cttcccagta ttcttgctcc ttttccagat caagcagtac cagcgcattc tgactaaacc
    74701 agtcatgcgg gaaacgcagt gtccagtgac tgtcatcagt aatcagtgtc aatgttggcg
    74761 gtgtggtggt tgcctgacgt tgattgttta gtaatacgcc aaggcgcaat agctgtatca
    74821 gtggcaggaa ctgtttcttc ttaaacaagg taaagcgcgg cagatcgtcg agcttaatcg
    74881 ctttacggtg atagcgcacc agtgtcgcca tcatcagctg ctgttcctga ttaaaacccg
    74941 gcaagtcact gttttgcaga atataagcgg agtggcgatg caaaccgctg tggttgatat
    75001 tcaacccgac ctcatgcagc atggcggccc atcgcagtag cgcctccagt tgcggatgcg
    75061 ccagcttcgg ttgctgttcc cgccactgtt cgtacatttg catagtggta tccagcactc
    75121 gtcgggcctg ttcgctgtcg atgtgatact ggttggcgag gctgctggcg gtgcgactac
    75181 gcacatcctg atgacggaaa cgtccttcca tttcatacag tacgccttcg cgtaacgccc
    75241 cgtcagaaag gcgcagttca cggatggcta aagcatcaaa cacaccgcat aaaatcgcca
    75301 gtccaggaac gaagactgtt ttccgctctt cggaaagacc cggtaaactc agcgatgcga
    75361 aattacggtg acgtaaaact tcttttacca gtttttccag acgttccggg gtaattatcc
    75421 cgtctttctc gcccatttcc attaacactt catgggcggc ttttatggta ccggaagcgc
    75481 ccattgccac gttccagccc tgaatacgga attgccaggt taaagtttcc agtttttgtg
    75541 ctgccgccat acgagcgcgc tgaaaattct ctttattgat gaccccgcca gggaagtaaa
    75601 gctgggcaaa gctgacacaa cccatccggc ggctttcaac gagaatcggt tcgaaatttt
    75661 caccaatcac cagttccgta gatccgccgc caatatcaat aaccagtttg cgacctttct
    75721 ccggttgggt atgttccacg cccataaaaa tcagacgggc ttcttcatta ccggaaataa
    75781 tttcaatcgg gtagggaatg accttttccg cgcgtttcag aaagtcagtg gcgttcagcg
    75841 cctgacgcag cgtatgggtg ccgactatac agacgctggc aggagaaaac ccttgtagcc
    75901 gttcggcaaa cagcgacaga cagttcaaac cgcgcgtcat tgcctcttca ctcaacatat
    75961 tatctggccc caggccgtcc gccagatgca cccgctgttt caggcggcca ataatctgca
    76021 tggcaccatc taccacacgg gctatgacca tgtgaaaact gtttgaacca agatcgaccg
    76081 cagcaaactc ctgcggacga ggggatttat cgtgtattgg catagggtta ttcaggttgt
    76141 tcgagtgatt tgatgtagtc gtaaatcgcc aactgcgccc gtactttgcg gcgattgccg
    76201 cggggaacgt agcgattact gagttcttta tcgatataac gtgctttgac cgtatcgctg
    76261 aacaatatgt cgatgatgtc cagcacccgc tgcttcaggc gcggatcgag cagcggtgtc
    76321 gccacttcaa tacgataatc aatattgcgc gtcatccagt cggcggaaga aaggtagacc
    76381 tttttatcgc cgccattttc aaaaatataa acccggtcat gttcaaggta acggtcaaca
    76441 atactgatgg cacgaatgtt gtcgctaatg ccttccagat tggggatcag cgaacacatt
    76501 ccgcgaacca gcagattaac cggtacgccg gagctggagg ccgcatacag acgatcaacc
    76561 aggcctttat cgacaaggtt atttagcttc agggtgatac cactgggcag cccttgctgc
    76621 gcgttggcga tttcgcggtc taccatttca tataacagac ggcgagagtt ttgcggtgac
    76681 accattaaat aatcaaatgt caccgggcgg tatgggtttt caataaagtt aaatacccgc
    76741 cgtacttcgt tggtgatacg cgcatctgcg gtcagcaacg aatagtcagt ataaagacgc
    76801 gcggtttttt cgttaaagtt cccggtcccg atgtgtgcgt aacggaccac ttcaccgttt
    76861 tctttacgtg aaatcaggaa cagtttggcg tgaattttca gccccggcgc agagaagata
    76921 acgtgcacgc ctgcttcggt caggcgcttc gcccagtgaa tgttggcttc ttcgtcgaaa
    76981 cgcgcctgta actcaaccac cacggtgact ttcttaccgt tatgtgcggc gtggatcatc
    77041 gagtcgatga tgcgtgaatc tttcgccacg cggtaaatgt taattttaat cgccagtacg
    77101 ctcgggtcga acgaagcctg acgcagcagt tccagcacat gctcaaaggt gtgataagga
    77161 taatagagca acacatcgcg ttcgcgaatg gcatcaaaac cattgcggaa ctgggcttta
    77221 tcaaaccaaa tgtggcgtaa acgcggcagt ggtttgttca ccagattggc tttgccgaca
    77281 ttggggaaat taataaagtc tttaaaatta tgataacgac cgccggggac gatggagtcg
    77341 tagcgggaaa tagtcagttt ttcgcgtaac acttcaacca gcgcattggg catatcgcgc
    77401 tgataaacaa aacgcaccgg ctcagcagtt aaacgctgct tgagactgga agacattaac
    77461 tccatcaggc tggcttccat ctcatgcact aaatcgtatt cggcatcgcg ggtcatcttc
    77521 attgaatagg cattcagcgc gtcataatca aagaagcctt tgaaaatatc atcgaggcag
    77581 taacgcagaa tgttatccaa aagaatcatc ggcttgcgtc gacgcggtgc ttctggcggt
    77641 aaattcacaa agcgcggcac tttatctgat gggatctcca gcagcgcgta acggatggta
    77701 tcgccacgga taatttccac cgccagatag gtgtaatcat ctttcaggaa ctgcactaag
    77761 tcagtgtcag gattgattaa aatcggcgta atgtgctgac gcagatactg cttaaaataa
    77821 tgacgcagcc agttttgttg attgacggag agctggcgtt cattaatcag gaagatctgg
    77881 ttgcgcgcca tctccagcaa tagctcgttg tagaggccgt cgaattcctg atcggctttc
    77941 agcacccggg actgaatttt gcccagtaaa tggcgggaat gagagttgga gccttgttct
    78001 tcgctaataa tgatgcgtcg cttcagttca gcgaagcgga ctttatagaa ctcatcaagg
    78061 ttattggaat agatccccag gaaacgcatc ctttcaatca gcgggttaga tttgtccgcc
    78121 gcttcctgaa gcacgcgttc attgaacgat aaccaactga gctctttttc gatgtatagc
    78181 ttttcctgac ccattaccac ttttactccg ttttattcac gggacactgc ctggatatta
    78241 tggcgagcaa tattggcaga tgtccaacta tgccagaaaa gggggaaaaa aactgctgga
    78301 gcttgcgatt tacaggtgaa ttgaaaaacg ccagcggcag agctggcgct ttaactacgg
    78361 ggcattactc gtcggcagcg tagccctgcg gcggcagacg ttgaccatcc agccacgcgg
    78421 cgttttcgtg cattttcaga cgaccatcgg caaaccagct aatcaccagt ggataaatag
    78481 cgtgttcctg ggtttgcacg cgggcggtga tgtcatcttc cgtatcacca gcaaataccg
    78541 ggactttcgc ctgtaaaata accgggccac cgtccagttc atcggtgacg aaatgcaccg
    78601 atgtaccgtg ctcttcatca ccattttcca gcgcctgacg atgggtgtgt aatccgggat
    78661 atttcggcag cagagaaggg tgaatgttca gcaaacgccc ggcatagtgg gagacaaacg
    78721 ccgggctgag aatgcgcata aaaccagcca gcacgaccac atcgggtgcg tacatgtcga
    78781 tttcatgaat caactcccgg tcataggctt cacgactgtc aaacgcgctg gcgatgagcg
    78841 tatgcgttgc aatacccgcc tggcgggcgc gttcaaggcc gaacgcgtcg gccttattgc
    78901 tgaaaactgc ccgtacggtg cctttaattt tgttagtttt acaggcgtca ataattgcct
    78961 gtaaattact tccgttgccg gaaataagca ccacaatatt cattattcga taaccacgcg
    79021 ttgttcggaa tcagaggctt tgatgatacc gattttccac gcgttttcac cgttggagtt
    79081 tagcagggcg agggctttgt ccacttccgg agcaggcagg gcgataatca tcccgacgcc
    79141 gcagttgaag gtgcgataca tttcatggcg ctcaacgtta cctgccgttt gcagccagtt
    79201 gaacacttcc ggccactgcc aggaagattc atcaatcact gcctgagtat tatctggcaa
    79261 tacgcgtgga atgttttccc agaagccgcc gccggtcagg tgcgcaatgg catgcacatc
    79321 gaccttttca atcaactcca gcactgactt cacgtaaatg cgggtcggtg ccagcagatg
    79381 atcggctaat ggcttaccat caagttcggt ggtttgcgga tcacaaccgc tgacttcaag
    79441 aattttgcgc accagcgaat agccgttcga gtgcggaccg ctggaaccga gtgcaatcag
    79501 cacatcgccg tcgctgactt tagagccgtc gatgatttct gatttttcta ccacgccaac
    79561 gcagaaaccc gcgacatcgt aatcctcacc gtgatacatc cccggcattt ctgccgtttc
    79621 gccacccacc agtgaacagc ccgattgcag acatccttcc gcgataccgc tgatcaccgc
    79681 tgaagcggta tcaacatcca gttttccggt tgcgtaatag tcgaggaaaa acagcggctc
    79741 tgcaccttgc accaccaggt cattaacgca catggcgacc agatcaatac caatggtgtc
    79801 gtgacgtttt aagtccatcg ccagacgcag cttggtacct acgccgtcag taccggaaac
    79861 cagcacaggt tcacgatatt tttgcggcaa tgcacacagc gcaccgaagc cgccaagacc
    79921 gcccatcact tccggacgac gcgttttctt cactacgcct ttgattcttc caaccagagc
    79981 attacccgcg tcaatatcaa caccggcatc tttgtagcta agagaggttt tatcggtcac
    80041 tgcttgggtc cccacgcgtt acttgcggta gaaaaataaa attcggcgca attctaacag
    80101 ggaaagcaaa cgtttgcgag actgctttac acaacctttt tgcacgtctt ttgcccaggc
    80161 acgcggcgaa agaagacttg tgccagggta aaggttagtt ttcggatgga ataatcttct
    80221 ttcataacca tttgaatata aaataacttt atctcaaacc gttatcattt tgactaaagt
    80281 caacgaaaag aatattgccg ccttgaagaa aggaggtata atccgtcgat tttttttgtg
    80341 gctgcccctc aaaggagaaa gagtatgaag atcgtggaag tcaaacaccc actcgtcaaa
    80401 cacaagctgg gactgatgcg tgagcaagat atcagcacca agcgctttcg cgaactcgct
    80461 tccgaagtgg gtagcctgct gacttacgaa gcgaccgccg acctcgaaac ggaaaaagta
    80521 actatcgaag gctggaacgg cccggtagaa atcgaccaga tcaaaggtaa gaaaattacc
    80581 gttgtgccaa ttctgcgtgc gggtcttggt atgatggacg gtgtgctgga aaacgttccg
    80641 agcgcgcgca tcagcgttgt cggtatgtac cgtaatgaag aaacgctgga gccggtaccg
    80701 tacttccaga aactggtttc taacatcgat gagcgtatgg cgctgatcgt tgacccaatg
    80761 ctggcaaccg gtggttccgt tatcgcgacc atcgacctgc tgaaaaaagc gggctgcagc
    80821 agcatcaaag ttctggtgct ggtcgctgcg ccagaaggta tcgctgcgct ggaaaaagcg
    80881 cacccggacg tcgaactgta taccgcatcg attgatcagg gactgaacga gcacggatac
    80941 attattccgg gcctcggcga tgccggtgac aaaatctttg gtacgaaata aagaataaaa
    81001 ataattaaag ccgactttaa gagtcggctt ttttttgagt aaagcgccta taacacataa
    81061 tacagaggat aatactatga cgcgccgtgc tatcggggtg agtgaaagac cgccactttt
    81121 acagacaatc ccgcttagtt tgcaacattt gttcgccatg tttggtgcaa ccgtcctggt
    81181 gcccgtctta tttcatatta acccggcgac tgtactgtta tttaacggta ttggaacgct
    81241 gctgtatctc ttcatctgta aagggaaaat tccggcttat cttggttcca gctttgcctt
    81301 tatttcaccg gtattgttac tgttgccgtt agggtatgaa gtcgcgctgg gcggctttat
    81361 tatgtgcggc gtgctgttct gcctggtttc ttttatcgtg aagaaagcgg ggaccggctg
    81421 gctggacgtg ctgtttccac ctgcggcaat gggcgcaatc gttgccgtca tcggtctgga
    81481 gctggcgggc gtagctgccg gtatggcggg tttactcccg gctgaagggc aaacgccaga
    81541 ctccaaaacc atcatcatct ctattaccac cctggcggtc acggttttag gttccgtgct
    81601 gtttcgtggt ttcctggcaa ttatcccgat tttaattggc gtgctggtgg gctacgcgct
    81661 ctctttcgca atgggaattg tcgataccac gccgattatt aatgctcact ggtttgcgct
    81721 gccaaccctc tatacgccgc gcttcgagtg gtttgccatt ctgactattc tgccagcggc
    81781 gttagtggtt attgccgaac acgtagggca cctggtagta acggctaata tcgtcaaaaa
    81841 agatctgctg cgcgatccag gtctgcaccg ttcgatgttt gctaacggcc tgtcgaccgt
    81901 gatctccggc ttctttggct ctacgccaaa taccacttac ggagaaaaca ttggcgtgat
    81961 ggcgatcacc cgtgtttaca gtacctgggt tatcggtggg gcggcgattt tcgctatcct
    82021 gctttcctgc gtcggtaaac tggctgccgc tatccagatg atcccattgc cggtgatggg
    82081 cggcgtttcg ctgctgcttt atggtgtcat cggtgcttcc ggtattcgtg ttttgatcga
    82141 atcgaaagtg gattacaaca aagcacagaa cctgatcctg acttccgtga ttttgatcat
    82201 cggcgtcagt ggcgcgaagg taaacatcgg cgcggcggag ttaaaaggta tggcgctggc
    82261 gaccatcgtc ggtatcggct taagtttgat tttcaaactg atcagtgtgc tgcgccctga
    82321 agaagtggtg ctggacgcag aagacgcgga tataacagac aaataatgta ccgaccgggc
    82381 agtgttgctg cccggttcaa acatcatggg attctgtggt aaacttctcg cgattttgtg
    82441 aaatcctggt tgaggtatct ctgaacacac cggcacagct ctctttgcca ctttatcttc
    82501 ctgacgacga aacctttgca agtttctggc cgggggataa ctcctcttta ctggccgcgc
    82561 tgcaaaacgt gctgcgtcag gaacatagcg gttacatcta tctctgggca cgcgaaggcg
    82621 cggggcgcag ccatctgctg cacgcggctt gcgcggaatt gtcgcagcgt ggcgatgcgg
    82681 tgggctatgt cccgctggat aaacgcacct ggtttgttcc ggaagtgctc gacggtatgg
    82741 agcatttgtc gctggtctgt atcgacaaca ttgagtgtat tgcaggcgat gagttgtggg
    82801 agatggcgat tttcgatctc tacaatcgaa ttctggaatc gggcaaaaca cggttgttga
    82861 tcaccggcga tcgtccaccg cggcagttga atctgggatt accggatctc gcgtcgcgac
    82921 tcgactgggg gcagatctac aaattgcagc cactttctga tgaagataag ttgcaggcgc
    82981 tacagttacg cgcgcgtttg cgtggttttg aactgccgga agatgtgggg cgtttcttgc
    83041 tgaagcggct cgacagagaa atgcgcacgc tatttatgac gttggatcag ttggatcgtg
    83101 cgtcgattac cgcgcaacgt aagctgacca ttccgtttgt gaaagaaatt ctgaagttgt
    83161 agataaggtg tttattgtcg gatgcggcgc gaacgcctta tccgaactac gcgaagttaa
    83221 tccatagtat tcgtaggccg gataagacgt ggcaagcgtc gcatccggca atgtgcttca
    83281 actagcgatg gagcacatct taacccacga tttccagtac ctgctccggt ggacgaccaa
    83341 tccgcgcttt gccattcgcg accacaatcg ggcgctccat tagcttcgga ttatccacca
    83401 ttgcctgaat cagcgcctct tcgctaagcg aactgtcagc caggttcagt tctttataaa
    83461 gatcctcttt ctggcgcatc aattcacggg cgctattcat ccccagcatt ttcagcaaat
    83521 cgcgcagcgt tgccgcatcg gcgggtgtct caaggtagag taccacttct ggctccacgc
    83581 cgttttcttt cagcaggttc agcgtttccc ggctctttga acagcgtggg ttatggtaga
    83641 tttttacctg tttggtcatt gttcttcctt taatgcgaat tacatcttgg tataaggctt
    83701 aaagcgttcc tgcagctggc gcaactggtc gatgcgcgca tcgtaacgcg cttgttgcag
    83761 gctgcctaat ttcacctgcg aactggcgct actcaacagc gaaatggcct gatcgagtcg
    83821 tccggcgagc gcataacctt ctgctcgcgc agccagctcc tgatcgcggt tatttagcgc
    83881 ggcttccgcc tgtgccagta aatcccagcc gttgctgtca tctttattat taaaggtgta
    83941 gcgattcaga atattggccg cttcttgtgg ttgaccgcct tgcagataag cgttcgccag
    84001 gttgagctgc aacaccggat tggtgcgtaa atcgcgggca tttttcagac gattgatcgc
    84061 ctcattggct ttgttttgcc caagatcgat atcagtagcc agatcgagat accatgcgtt
    84121 gccaggttct gccgccagta acggttgcag cgttttacgc gcctcgtcgt atttattggc
    84181 ttccatcgcc tgtaaagcac gaccatattg tgctgctcgt tgctgacgaa cgtttccttt
    84241 cgcccattca tccagcaaat cactggtgag ctggttacgt ccggaattat acatccccag
    84301 tgtgcgcgct ttcgccagat agaaatcttc cgacgactgc accaccatcg ggcgcatctg
    84361 attagcacgg ttgcgggcat ctgccagacg actttccggc aacgggtgag tcaataaaat
    84421 ttccggcgga cgcgaggagt aacgcgcctg atcgagtaat ttttcgagga aggttggcat
    84481 cgcctgcgga tcgaatcccg agcgttgcag cacctgaata ccaatgcggt ccgcttcctg
    84541 ttcattttgc tgggtgaaac tgatcatccc ctgacgcgtt cccgccagtg taccggtcag
    84601 cgccgccatc cccgcctgcg gactggccat cgccagtaaa atagaaccta acgcgccgac
    84661 ccaggtcagc ggcgcgctgc gctgctgatc ttccatcgct cgcgccaggt gacgttgggt
    84721 gacgtgggag atttcgtgcg ccataactga agccagttga ctttcgttat cggaataacg
    84781 gaacagggca gagtgcagca ccacgttgcc gccaaagaaa gcaaaggcgt taatttcgtc
    84841 gttgttgatc agaaagaaat gaaacggtgt cttaaccgaa ttggcatgcg aaaccagacg
    84901 catccccagc gaattaatat attgcgttaa cagcgggtca ttaattaacg gcgcgctgcc
    84961 gcgtagctgg cggacataat agtcgcccat ctgcatttcc tgaccaatgg aaagcgtgct
    85021 tcctgcggag gttcccatat ccggcaaggt gtctgcgctg tcggcaaacg ccggggctac
    85081 ctgaccaatg gtcatagcag caatgagggt tgcaaccagg ttttttttca actgcctgaa
    85141 cataacctct atcctgtatt tctgaagata gtcatttgac cgatactgtt aaatatcgtt
    85201 cccaccgcgc cgcctttgag tgtaacggcg aagattagcc cactcaaatg acttttcagt
    85261 ttcctgaatc cgtcataaaa agcgaagtct tttttgtgac atttcgatac aattgcggat
    85321 cgcaatcccg ctcttgaggt tcagggaagg tctttatgct cgaaatgttg atgcaatggt
    85381 atcgccgccg ttttagcgac ccggaagcga ttgccttgct ggttatttta gttgccggat
    85441 ttggcattat ctttttcttt agtggcctgc ttgctccgtt gctggtggct attgtgctgg
    85501 cctatttgct ggaatggcca actgtgcgcc tgcaatctat tggctgctcc cgccgctggg
    85561 cgacgtcgat tgtattggtg gtttttgtcg gtatattgct actgatggcg ttcgtggtac
    85621 tgcctatcgc ctggcaacag ggcatctact taattcgcga tatgccgggg atgctcaata
    85681 agctttctga ctttgccgcc acgttgccgc gccgctatcc ggcgttaatg gacgcgggca
    85741 ttattgatgc aatggccgaa aatatgcgca gtcggatgct gaccatgggc gattcggtgg
    85801 tgaaaatttc cctcgcctcg ctggtcggtt tgctgaccat tgccgtctat ctggtgctgg
    85861 tgccattgat ggtcttcttc ctgctgaaag acaaagagca gatgctgaac gccgttcgtc
    85921 gggtgctgcc gcgcaaccgt ggactggcag gacaggtgtg gaaggagatg aatcaacaaa
    85981 tcaccaacta tatccgcggc aaagtgctgg agatgatcgt ggtggggatc gccacctggc
    86041 tggggttctt gctctttggg ctgaactatt cgctgctgct ggcggtgctg gtcggcttct
    86101 cggttcttat tccgtacatt ggcgcatttg tggtgaccat tccggtggtt ggcgtggcgc
    86161 tattccagtt tggcgcaggc acggaattct ggagctgctt cgcggtgtat ctgattattc
    86221 aggcgctgga cggcaacctg ctagtaccgg tgttgttctc cgaagcggtt aacctgcatc
    86281 cgctggtgat tattttatcg gtggtgatct tcggtggttt gtggggattc tggggcgtat
    86341 tcttcgccat tccattggcg acgctgatca aagccgtgat ccacgcctgg cccgatgggc
    86401 aaatcgcgca agaataatct tcagcccgac gaactgtttc gccgggctga tttttcagga
    86461 ttcctgacgt aaataaatag cccgataaca catactcacc agcactgcac cgccgataat
    86521 attacccagc atcaccggga gcagattggc ggtaataaaa tggctgaccg tcagtgccgg
    86581 aaaattgtct gcgctactgt gcgccagttg ccagaaggag gtaggggcga aatggcgaat
    86641 ggcaatggcg aacggaatca caaacaaatt ggcgatacag tgctcaaagc cactggcgac
    86701 aaacagggtg atgggcaaaa tcatggcgac gattttgtcg cataacgaac gcccgcaata
    86761 actcatccac agcgccaggc aaaccatcag attgcacata atgccgaggc tgacagattc
    86821 agtaaatgta tgatgcattt tgccctcggc gcagtgtaaa accgcgactc cccacatcgc
    86881 gttttcactc atcaccagcc cggaaaacca gattaacaaa ctgaaacagg caatacctgc
    86941 cagattaccg caggccacca gaagtgcgtt aatcagccaa gttcgccaac taataacgcc
    87001 ccgacttttt gccattaccg tcattaccga cgaggtgaac aggttggtgc cgcaaaccgc
    87061 cagcaaaata aagccaagtg taaagcaaag gccgcccacc agatgggtta atgcctgtga
    87121 agacggggta tcggcgataa cggaaaggta aaaagtaaat ccgatcgcca taaacacgcc
    87181 agcggacatc gccattaaaa agaccgacac tttactgcgg gcaattttat gggcggcaat
    87241 ccgttcagcg attgccgctt ttctggcgct caactgcaag tcgaagagag tttgtttctc
    87301 atgcatactc ctgcaaaagc agattacaac acctcgcgaa ccgagattcc cagacgctgc
    87361 attcgtgaca gcagcgtggt gcgcttcatc cctaatcgtg tcgccgcgcc acggggcccg
    87421 gcaacaatgc cattggtttc tcgcaatacc tgaacaatgc gctgacgttc ttcttcgtca
    87481 ttctctggcg tcgtcgggtg cagcaactgc gccattgaac tgcgaagcgc tgaatcttca
    87541 tttagcgtcg gcagtaaacg gctttgtcgg acattaagat gtaaattcag actgttaccg
    87601 cgagtcagca gtaccgctcg ctcaatcacg ttttccagct cgcgcacgtt gcccggccag
    87661 tcccacgaca tcaactggcg tagcgcctcg gtcgggatgg cgtcaattga acgattcata
    87721 tggcgcgcca ttttttgcgt gaaatgcttt gctaaaagag ggatatcttc cggacggtcg
    87781 cgcagcggcg gcaattccag tgggaagaca ttcaggcgat aaaagagatc gctgcgaaac
    87841 tggcgatctt caaccatttg ccacaaatca cggttggtgg cggcaatgac tctgacattt
    87901 accgggatcg ttctactccc gccgagacgc tcaatctccc gttcctgcaa tacgcgcagc
    87961 agtttaggct gaagttctaa cggcagatcg ccaatttcat cgagaaacaa cgtgccgcca
    88021 tcggcaattt caaaacgacc acgatgggta ttaatcgcac cagtaaacgc ccctttgtca
    88081 tgaccgaata actcactttc cagaagactg gcggggatgg cagcgcagtt gattttgacc
    88141 agcggcttgt cgcgtcgcgg gctaagttga tggatcgctc tggcgatcac ctctttgccg
    88201 gttccggttt caccgcaaat caacaccgta ctgtcgctct tcgccacaat atctacctgc
    88261 tggagtaggt cttccattgc ctggctttga tagataatgt caccgatgcc cagattcgaa
    88321 aggagctgct cgctaagctg gtggttttct tgctgcaaac tttcctgcaa atcggtcatg
    88381 ctacgccagg catcggcatt gccaacggca atagcgatgc gatcggctat gtgttgtagt
    88441 agctggcagt tttcctcact aaagagagtg gaagaggtat gcgccagcaa caatgcaccc
    88501 ggtgtatggt tgccaaaggt aagcggtata aggagcgcag attcgcagcc gttagatgca
    88561 agtaagagta ataacgggtc gcgttgccag agaaacagat cgtctgcacg gtgcgtcaag
    88621 gtcggttgtc gggtttgtag cgtttgtgtc agcaatacac tgtcgccagg catactgcgt
    88681 ggcagacacg cacaatgtga ggcagaaaga tcgctgcacc acaggctaaa cttctcgttc
    88741 tttcgatgat cgcccagtac catactgact gaagccagac cgaaaaaatg atggatctca
    88801 cgagcgacgt cagcgatcag atcgtcgaga tcaaaatgtg acagcactgc attagtaata
    88861 tccaccagta cccgatgatg atcgcgatct ttctccagca aacgcagcgc cacctgctgt
    88921 tcttcatcat tgagccatga ttgcagaacc ggggtgatta tccgcgccag ccagttaaac
    88981 agtgtgcaat cctggggagt aaaacggctg ccgtgggtac gaataaagcg tagctccgcc
    89041 attccactac tgccgagaag gacggcgtga cgcgaataat cgaccatctc gccctgatac
    89101 tctgttgttg ccgtcacatc gctgccatca tcatggtagc ggtaatagaa gttgcttttg
    89161 agaacatgca gttcaataag ttgtaccggg ctgaacggcg gcggcatcgg gatgaaggcg
    89221 cgtaataaag acgccttacc gtgtttctgt gctaaccgct ccgcgagcat tccgtttacc
    89281 gcttcaattg ttattccttg tggcggggca aacatcgcct cgtctgacat agccatcaac
    89341 agtccttatt aatgagaaat ccttctcacg caatttttct ggccatcaga tagatggccg
    89401 gttcctgcac aatttcatcc aacagatgaa tgaattgaat gctacgcgcc tgccacacag
    89461 acgtcgcgtc atctgccagt ggcgcgaatg cccgggtcaa cagtgcggtg tggctggcgt
    89521 caataacaat ctcaccaaaa gtcatcaccc ccagcatctt acgtcgggct tgctcctctt
    89581 cgaccagtgc aagccaatct tcgtattccg tcagtgggca gcggaaggcg acattcagac
    89641 aatcaatcac gccaacgtga tgaccgatag ccagcgagta atacattacc tgggagctgt
    89701 gttccggcat ctcgtcgcta ctggcgacaa acttttttcg cagcgtccag aaaacaattt
    89761 ccccgcactc ctcagccatg taacccccgg agaacgcgaa agagttgctg aacgatacta
    89821 ttgagacgcg gatcgtcagc ttcgcgcaac caggtgttaa cccgatttcc tgtaggatcg
    89881 tcgcttaaat ggcgcaggag ccgatcgcaa atttctcgcc cctgacgata gcccgccagc
    89941 tgccgcgctt ctcgctcaat ggcgatacgc tgtgatggcg ggatctgcgg ccacagcggt
    90001 tgcatggtca ccccggtggg atcgcgataa tccacagcgt gaatcttctg ttgcagcaaa
    90061 ccgagcgcca cggcgaaacc gtgaatggtg gcggccggtg ttggcgggca gccggggatc
    90121 caaacatcaa tggggacaat ggtgtcgctg ccgccccaga cgctgtagag atcgtggaaa
    90181 atccgccgcc ggcaccgcac gcgccgtagg aaacacagat tttatgatcg ggggcagact
    90241 catacgcccg aagtgcaggc atacgcatcg cccgggtgag tgcgccagta aataacaaaa
    90301 tatcggcgtg acgcggtgat gaaacaacct taatgccaaa acgttctgcg tcgaatactg
    90361 gtgtaatggc ggcaaaaatt tcgatttcac aggcgttgca gccaccgcaa tcgacgcgat
    90421 aaacgtaggc tgagcgacgg atatcctgta gcaaatgccg cttcatcttt tgcgtttgct
    90481 cgtccagcgt gatgggctgg ctgacatatt gcgtaagcac tggactcata gctgctcctt
    90541 agccaccagc ggtacatctg tatcgtcgtt gagcagcgtc gcgcgttgtt tgcactccgg
    90601 gcagacgctc gcttgcgccc ataacatttc gcggttttgt ggcgcatttt gttgctgtgc
    90661 caacaattca gcagccagtg cgacggtttt ttgctgggca aacgggcgtt cgcaacggct
    90721 gcaacgttgt agatggaacg tcgcgcgggt atagagatcg gctttattgg tgacggtcag
    90781 ttcaaagtta ttggtaagct gatggctctg gtcgggcaca cttcttcaca acgtccgcag
    90841 taaatacaac gcctcagata gagctgccag gtgcgcgaat tttgctggtc gtcggtctgg
    90901 atcgtcagcg catttgccgg acaagcacag gcgccgcagg caatacattg gctgggcatc
    90961 aggtccggtt tcccgcgaaa gcctgggctg acctccagtg gcgcgaaggg atatttcacc
    91021 gtcgcggttc cggcgcgcat aatagttttc agtaacttca gcatcttctg tccttacttc
    91081 agcggcgaac ggttacgatc aatgccgtag cgttcgatct ctttatacgg cacggttttt
    91141 gactggcgct tgcgcacatc taccagcgtc acacggtcgg tacaggagta gcagggatca
    91201 aggctaccga taatcagcgg tgcgtcagaa acggtattgc cgcgcagcat gtaacgcaac
    91261 accggccagt tggcgtaggt ggcggcacgg cagcgccagc ggaacaattt ttggttatca
    91321 ccgagcatgc tccagtgcac gtcttcaccg cgtggcgctt caacaaagcc cagcgcgaat
    91381 gcgtgaggtt tatagctaaa gccttcggtc agcagtgggg tatccggcat gttgtcgaga
    91441 gcaaattcta gcattgccag cgaatcaaac gtctctttga cacggaccat cacgcgggag
    91501 aaaacatcgc cgccggtaaa ggtaaacagt gtttttggaa tattgccgta gtcggcgtag
    91561 gggtgatcaa agcgcaaatc acgggcgatt tgtcggtcga gaatgccaat gccctgagtg
    91621 cgttgttcca tattcggcgt agcaagcagc atctctacca gctccgacac gtcggcgcgc
    91681 atctcgcgca ccagtttcag cgtttgcaga cgttgctctt tgagaatatc gcggcgaaca
    91741 ccaccaatca gattcagacc gtaggtttta cgcgacccga tcagcaattc cgccatcgtc
    91801 atcgactttt cccgcacgcg gaaaaattgc ataaagccgg tatcaaaacc aacgaaatgg
    91861 caggagaggc caaggttaag caaatgactg tgtagccgtt cgacttccag cagaatcgag
    91921 cgaatagtat gtgctcgttg cggcacctca atccccagtg cattttcaac cgagttggta
    91981 taggccacac tgtgggcaaa accgcaaatc ccacacacgc ggtccgataa gaaggtcact
    92041 tcgttgtagc ccatccgcgt ttctgccagt ttctccatgc cgcgatggac ataaaacagg
    92101 cggtaatcag catcgacaat ttgctcgcca tccacaaaca agcggaagtg acccagttca
    92161 tcggaggtga tatgcagcgg gccgacaggg atcacctgcg catcgctgtt gccctcattg
    92221 ataaacggat acgtttcgga atcagtcgtc ggttcagggc gcagtcgata atccatcgca
    92281 tctttgcgca gcggatgcat atcttccggc cagtcatcgg gcaacaccag gcgacgctga
    92341 tccggcaggc caaccggaat cagcccgtac atatcgcgaa tttctcgctc gccccagacc
    92401 gcggcaggga cgcgcggtgt gactgacgga aactcccgac tgtcggcatc gaccagtgcc
    92461 ttcaccacga tccagcattt ttcggcccct tccattgaaa gggcataata aaccgcgtaa
    92521 tgaccgttaa gtgtccgctc gtcgttgcca aacaggactg gaagccagcc atcatgttga
    92581 taataaagat aatgtacaac gtcaggcagc agattgattt tcaccgtaat ggtgacctgt
    92641 tcaggcgttt gtcgctcttc atccagcacc gcgccgggga actgcgtttt cagggcggcg
    92701 agaatcgctt cgccacgatt tgacgatgaa ttaacgttca ctgtgtttct ccgaaacaga
    92761 tgcggtgcct gaaggcaaaa aatcatgcca ggtgctacgt tgtgcaggca ggtcgtgcgt
    92821 ccctgagagg actatagtgg aagcgcccgc caggatcctg atgacaggtt gtggaatatg
    92881 cgttcccatc gccagcatca tgaccagcag aatcaccatt ggcgaggtgg tcaaccagcc
    92941 gagatcaccc cggttaacgg cctgcggcgg tttcgccatt aacacccgcg ctgccatccg
    93001 taccaggccc gccagcacca gcgttaacag caataacagc aggacgataa tcagcaggtg
    93061 attacgtgcc agtccggcgg taatggtcat aaattcgcta agaaaaatgt tgaagggcgg
    93121 catccctgcc agcgccagcg ccagcgcacc gccgccaaac agcacggcgg taaatggcat
    93181 gattttgagc atcccacaga cgacgttgag atcgcgcgtg ccgtacttga gcagtacatt
    93241 gccggaaccg cagaacagca gcgtttttgc cagactgtgg tttaaggtgt gcagcagcgc
    93301 ggcaaaaatt cccagtggcc cgccaatgcc tagcgccacc gcgaccagtc ccatgttctc
    93361 cacgctggag tacgccagca gacgcttaat gtcccgctgt accagaatga aaaatgccgc
    93421 cacggcaacc gacaacatgc cgaagatgag caacaaccgg ttggggaaat cgctgccgat
    93481 ggcctggcag ataatgatgt aatagcgaat tagcaccaac agcgcgcagt tcagcaatac
    93541 ggcggagagc agggcgctga ccggactcgg tgcttcactg tgagcatccg gcagccaggc
    93601 gtgcatggga aatagcccgg ttttggtgcc aaagccaatt agcacaaaca caaaggccaa
    93661 cagcattaat gttgggtcaa gcaaggacga ttgcttaaga acctcgctcc agaatatcgc
    93721 catttctgcc tgcggcataa cgctggcgac gttggcgtat accagcacgg taccgaacag
    93781 accaaaagcg acaccaacag tacaaataat gatgtacttc catgctgctt ccagcgatga
    93841 acgctgaccg taaatgccta ccagaaacgc cgagcttaag gtggtggctt cgatcgccgc
    93901 ccacatcaca atcaggttat tgctggtaac aaccagcagc atggtaaaca aaaacagatg
    93961 gaagaaaccg tagtaatcgc acagcgtaac gggggaaagc tcgccgtgtg ccacttcatg
    94021 acgcatgtag ccaatcgagt aaacaccggt gagaaagcca atcacaccaa gaatggcgag
    94081 gaacaaaccg cccagaccat caatatgaag ccacagtccc gcagcgaata tttctcctgc
    94141 atcagcggca gtttggacca cccagagtgc cagaatcagc agcagtgtga tccctaagct
    94201 atgtaataca gtcaccgtac aagtcgcaga gagcccccgt ttccggcagg caaaacagag
    94261 cagcgaaaaa agcagcggcg tgagcaggag taaagcgaac atcacagaat aactcatctc
    94321 attatccctt cagcgcggtc aagttgttca cgtccagcgt gccgtgggta cgccatattt
    94381 ttcttgccag taacaccatc acaatgacgg cgaagatggc gtcggtagcg atacctattt
    94441 ccaccagttc cggtgctcgc caggcaagaa gcgccagcac cagatgggag ccgttttcca
    94501 tcaggcagta accaaaaatt tgccgcagga tattgcgctg gctgacaatg cacagcaggc
    94561 caagcagaaa atgacctaac gctaccgcca gcgccggttt cagcccggta gccatcggta
    94621 gcttcacggg ctgaacgaca aatgcgcaaa gcaggacaat taacgccgcg agcagtgcca
    94681 tcattgccgg accgaataac gctttttccg ggatgttctg gggaatattt cgtgcagcgt
    94741 aagtcatgat taacggtacc agcagcactt tggtgataaa ggcgctggcg gaccagatca
    94801 gcagttgctc tgcggcgaac aggcacgaga gagtggcgaa aatagacacc agcaccagcg
    94861 actggcaggc gtaaaatccg catgacaggc gatagctttt gacgctaatc acaaacagcg
    94921 atgtcagcat catcagtccc gccagattat ttacgatcat agaaccggtc attcatcatc
    94981 tccttactgc aaccaggtcg cggcgattac gctggaaatc agcaacatca caatcagtac
    95041 aatcaacacc aggcgcattg accctggcag cggtgcggca tcggcgacgg cctcgctcgg
    95101 tttgccaggc acaacgcgac caaaccagcg aataaaccag gcgaaactgg cgaccgattc
    95161 aatcatcagc agaatcatgg cgggcagcag gatccagtac tccactgaca acgcaaaacc
    95221 ggcagcaaac agcgggaatt tactgaagaa gccgttgaac ggcggcacgc cggtaatcgc
    95281 cagcgctgcc acgcagaaac ccacgcctgg caacggcagg gtgtgcaata cgccacgcag
    95341 acgcggcaac aagcgcgtgc cgcagctgta actcagcgca cctgctacaa ggaaaaacag
    95401 gcttttagcg aacgcgtggt tgacgatgta ggcgatgctg ccctccagtg ccagccgccc
    95461 actttcacca tcgatgcggc gtggagatag gcgctgatcg gtgttggcgc ttccattgca
    95521 tccggtagcc acgcttgcat cggtagctgg gccgatttcc cccacgcggc aaacaggatg
    95581 ccgccataaa ccagataacg tgcgtcgcca tgtaactcgc tcatcgcgct aagcacaaac
    95641 gttccggtct gcaaaaacag cgtggcggcg gcaagataca accccaacga accgatatgg
    95701 gtgataagca acgcttttag tgctgaacgc tgcgctttat cgctctggta ataactgatc
    95761 aacgcccagg agcagccgcc cgtaatttca aaaaacaaca actgaccgag cagcgtcgag
    95821 gagagtacca gtcccgccat cgcgccgata aacaccagca aaaatgcgta ataacgattc
    95881 gtgccgttat gcgggtgttc gcgattttta tccgtcagat aacccgtgga gtagatcgtg
    95941 accagcaaac cgagaaacac caccacaaac agaatcagcg tactcacgcg atcaatgacc
    96001 aggccaaaca atgccacatc ccccacgttg accaacgtca acgtgacggc aactttatcg
    96061 gcctgataaa acgcggagat cagcgacaac atgcacagcg tggtcagtgc ggcgaacaaa
    96121 acccccattc ggcggcccga cgttgtggcg aaaacgaaac gaccagtgcg ccgataaaag
    96181 gcagcattaa cgtcgtcaga gcaagatttt ccatattccg tcagtgctcc ttacagaccg
    96241 gttaaccaga agacccatgc aagcgcagca aggctgaagc caagccaggt cacatggtga
    96301 atgagtaaaa aacgcccgcg tgccagcgtg ttttctgcga ttgaggccag tacaaaaatc
    96361 agcaaaacct tgagcagcgt aacgacaagt gaagtcagca ggcaggcgag agaaagttct
    96421 tgcgcgcgcc caaagggcag aaacagggcc acaaacagtg ctgccatcac gacctgtttc
    96481 agccccagcc cccatttcgc tagcgccagc ccggcaccgg aatattcggt cagcgggcct
    96541 tcctgtaatt cctgttctgc ttcagcaaca tcaaagggaa tttttcccat ctcaatgaag
    96601 caggcaaaac cacaggccag taacgccagt acggtggtta gcggcgagtt ccagcccgtt
    96661 gccagcgtat tgctgatcat ctcgatatgc gtggaacctg ctatcagcgc caataccagc
    96721 agtgagagaa tgagcatggg ttcgaccaga atgccgagcg tcaactcgcg actggcaccg
    96781 actcccgcaa acgggcttcc ggtatccagc ccggaaagag caaagaaaaa acgaaacagg
    96841 gcaagaagat agataagggt gatcagatcg ccgccgcccg caaaagggga aacggtaata
    96901 aaaagtggta gggccatcgc cagcaccagc atgctgctga ttaataccca cggcatcagg
    96961 cggaacatca gacctgaaga tataggcgca acttcctggc gtttaaacag tttgtggata
    97021 tcgcgataat cctgccagat ccccggcccg cggcgggagt gcatacgcgc gcgtatctgc
    97081 cgggaaatac ccgtaaaaag cggggttagc atcagcagaa tcacggcctg tgctaacgca
    97141 aaaatgacca gatatccgtc gtaaagagtt tgtctcatgg tgatttcctt agacggcaat
    97201 agcgattagc agcacaacca gtgcggcgac cacatacagg caatagagac gaaagtcgcc
    97261 gctttgcaga tgctgtattt ctttggccag ccgttgggtg gcgctcacga tggggcggat
    97321 cacccgctca tcccagaagg gttctgtgct ctgagccctg gcggtgacgt gcgcaagacc
    97381 tttatttagc ctcagcgtag ggtcgaactg ttgtcgtaga cgaaatagcg cagaaaagac
    97441 cacacgcagc gactgcatca cgccattgcc tgacggggcc atcgcatttt cccagccgta
    97501 gccgcatgcc caggcatctc ctgtgcgacg aaacgctgcg cggcgcgaac gacaccacag
    97561 ccagtaaagg ccaggcagca aaggcatcgc cagtagtaac agcaacagta atgagggggt
    97621 gacctgtgta tgaaacgtgc cgggtacaag tgctattccg ctggcgacag tgacgggagg
    97681 ggtattggta aacgcatggg caatatgcat tatcttcggt gccagccaac tggcactaag
    97741 cgcaattaat acgcagagtg ccgcgagcag tagcatggcg acgatcatcg tatttggcac
    97801 ttcctgtgcc tcttcagcgt gtgtactgcg cggcgcacca cagaaagtaa taccgtacat
    97861 ttttacgaag cacattactg ccagcccacc agtgactgcc agcattacca tagcaatagg
    97921 acccgcaagt tgtagcgcta cggcttccac acgacttagt gagaacagcg actgccaggt
    97981 gtaccattcg ctgataaaac cattcagcgg aggaatggct gatatcgcga ggcaaccaat
    98041 caggcatgct gcggctgtcc acggcatccg tttcgccagt gcccccattt tttccatgtc
    98101 gtgggtatgc aaacgcgaaa taatcgcgcc cgcgccgaga aatagcagcc ctttgaacag
    98161 cgcatggttg agcagatgaa acagtgcgcc gagcagtcca accacggtga gcagcgggtc
    98221 gtgcagtgac agaccgacca tcgccacacc gactgccagc aaaataatgc cgacgttttc
    98281 gacggtactc caggccagca gccgtttgat atcctgttcc gccagcgcat acagcacgcc
    98341 caggagcgcg gagattgcgc cgatcgccat caccagaatg ccccaccaca gcggcaaacc
    98401 cgtttgcgcc agcaggtcca tcgctacttt caggatgccg aaaataccga ttttgaccat
    98461 tacgccagac atcaacgccg aagcgtgcga tggtgcggca gggtgagcgc gcggcaacca
    98521 gctgtgcaac ggcatcatcc cggctttcgc gccaaaaccg aaaaaggcca gcaggaacac
    98581 cgccgacgcc agccccggag aaagtgaaag cgtgcggaaa ctggcaaaat cgaggctgcc
    98641 gctttcgcgc cccatcagca agaaggcgat cataatcagc accgatccgg cgtgggcgat
    98701 aaaaaagtag agcatgccag cgttgatcga cgttttatcc tgcctggcaa tgaccagaaa
    98761 ccaggaagac agcgacatca tttcaaacag cacgatgaac caaaaagcgt tgtccatcac
    98821 cagcagggca accatcgatg cgatgaaaag attcataaag aagcccatcg ccgccgcgcc
    98881 tttgccctcg tattcgcgca tataagtcaa tgaatagagc gaacaaacca ccaccagcaa
    98941 ggagataacc agcaccataa atgccgagag gctatccatt cgcagggtaa aatcggcaaa
    99001 gtcaaaaggg gtggcaaaac gggcgactaa agttacacca gcatgtaatt gcgtaattcc
    99061 gctgatgatg ccaatcacgc cgcccaccag cgatgtgatg ccggaaagct taatagccag
    99121 tctgtccaga ccgagtaaaa acagcgaagc cagactggca aacagataga ggatcagcga
    99181 ccaggttaat aattgcaggg catccattag cgttgctcct gagtgaggga aaggggatcc
    99241 tccccgccat tggcaaacca gcttgcggca aggcgctgtt tttctttcat ctgtcgttgc
    99301 aggctatcgt cggtgatcag ccgtaacgcc tgattcgggc aagcgcgaac gcaggccgga
    99361 ccttctggca agaaatcaca caggtcgcat ttcaccgcga cggtctggac acccggttcc
    99421 cagcgcagca atgcatgttg gggcggcacg ttttcttcgc cgtctttgag tgagccttca
    99481 gcctgaaaaa catattgcgc aggggcattc accggacggc ttcctgaagc gctgattgcg
    99541 ccaaatgggc agaccacggc gcaaagcttg cagccaatac agaggctttc gttgagttgg
    99601 atcgcatcat ccctctggga gatggcatta accgggcaga cctgcaggca aggggcttcc
    99661 tcacagtgat gacacacgac aggggcagtg agtgttgacg tcttcgccag ggccaggcgc
    99721 gggtgttgct gtaaaccttg cgttttatgc acgtccgaac aggcagcgag acaggtatta
    99781 catcctgtac accacagtgg ttcggccacc acaaagcggt tcatgtcggc tccttgaaaa
    99841 tgatatgaaa cattgcattt catattgcat aaaggatgcc attctgatta actcaatata
    99901 ttcaataagt tatgtattga ctggattctg aacggtacaa aaatgatggt cattaacgtt
    99961 cagcaaaaaa tggattcgac acccgtgtcg caggggaaag cgagaatgtg atcttgatca
   100021 cgagaagtga ggtatgctgg ccgcaagcgc agccagcacg gaatggagca aagtaatcag
   100081 gcgtgttctt tcagccagtt cagcacaacg tcgtggtgat tgctggtttt gaaatcgtca
   100141 aagacatgtt cgattttgcc atcagcgtca atcaggaagc tgatgcgatg aatgccatcg
   100201 taggttttgc ccatgaagga cttttcaccc cagacgccga attgttcgca cacctggtgg
   100261 tcctcatcag ataggagcgt aaagttaagc agctcttttt ccgcaaaacg ggagagtttt
   100321 tcgggtttat cggtgctgat acccagcaca tcaacgcccg cttttttcaa ctcatccatg
   100381 ttatcgcgta agccgcaggc ctgtacggta cagccggggg tcatggcttt cgggtagaaa
   100441 taaaccagaa cacgctgtcc ctggaagtcg gtcaaattaa cttgttctcc gtcttgatcc
   100501 ggcaagctaa atttcggtgc gatatcaccg gctttcagtg gattcattac ttaactccat
   100561 cctgttcatc atgttgggaa taattgacga cgttaatact gccttgtgca ttgagttctg
   100621 tacatagggc tttgaacgct tgctcaatat ttgctgcgtc cgcagatgcg gggctgtggg
   100681 cggttatctg aatatgcaac tgcgcagccc gttcattttc agcaggttgc gtgcgcgaca
   100741 ccagctccgc aatgttcata tgatgcgcgt cgaaaagtgc tgtgaagcgt tcaattaaat
   100801 gcggggagtc tgccacatcg acctgaaccc agacagatgc tggcattggc ggacgcggac
   100861 gcgccgtcgt gcgcttcatc acgattaaaa gatccagttc ggcacctttc aacggtaacg
   100921 ttgattcaat cagagtaatg gcattccatg aaccggaaag cagcataata aacgtgaact
   100981 cttctcccag catcgccagg cgactgtctt caatattaca gccgcaacta ctgacatgac
   101041 gggtgatggt gttcacaatt ccagggcgat cggcacccaa cgcagtgatc accagataat
   101101 gttgcgatga cagtgtcaaa ctggttattc ctttaagggg tgagttgttc ttaaggaaag
   101161 cataaaaaaa acatgcatac aacaatcaga acggttctgt ctgcttgctt ttaatgccat
   101221 accaaacgta ccattgagat acttgtttgc acagaggatg gcccatgttc acgggaagta
   101281 ttgtcgcgat tgttactccg atggatgaaa aaggtaatgt ctgtcgggct agcttgaaaa
   101341 aactgattga ttatcatgtc gccagcggta cttcggcgat cgtttctgtt ggcaccactg
   101401 gcgagtccgc taccttaaat catgacgaac atgctgatgt ggtgatgatg acgctggagc
   101461 tggctgatgg gcgcattccg gtaattgccg ggaccggcgc taacgctact gcggaagcca
   101521 ttagcctgac gcagcgcttc aatgacagtg gtatcgtcgg ctgcctgacg gtaacccctt
   101581 attacaatcg tccgtcgcaa gaaggtttgt atcagcattt caaagccatc gctgagcata
   101641 ctgacctgcc gcaaattctg tataatgtgc cgtcccgtac tggctgcgat ctgctcccgg
   101701 aaacggtggg ccgtctggcg aaagtaaaaa atattatcgg aatcaaagag gcaacaggga
   101761 acttaacgcg tgtaaaccag atcaaagagc tggtttcaga tgattttgtt ctgctgagcg
   101821 gcgatgatgc gagcgcgctg gacttcatgc aattgggcgg tcatggggtt atttccgtta
   101881 cggctaacgt cgcagcgcgt gatatggccc agatgtgcaa actggcagca gaagggcatt
   101941 ttgccgaggc acgcgttatt aatcagcgtc tgatgccatt acacaacaaa ctatttgtcg
   102001 aacccaatcc aatcccggtg aaatgggcat gtaaggaact gggtcttgtg gcgaccgata
   102061 cgctgcgcct gccaatgaca ccaatcaccg acagtggtcg tgagacggtc agagcggcgc
   102121 ttaagcatgc cggtttgctg taaagtttag ggagatttga tggcttactc tgttcaaaag
   102181 tcgcgcctgg caaagattgc gggtgtttcg cttgttttat tactcgctgc ctgtagttct
   102241 gactcacgct ataagcgtca ggtcagtggt gatgaagcct acctggaagc ggcaccgctt
   102301 gcggagcttc atgccccggc tggaatgatt ttgccggtga cctccggtga ttatgcaatc
   102361 ccggtgacca acggtagtgg tgctgtcggt aaggcgctgg acattcgtcc accagcccag
   102421 ccgctggcac tggtttctgg cgcgcgtacc cagttcacgg gcgataccgc ttcattgctg
   102481 gtggaaaatg gtcgtggcaa tactctgtgg ccgcaggtgg ttagcgtgct gcaggcgaaa
   102541 aactacacca tcacccaacg tgatgatgct ggtcagacac tgaccaccga ttgggtacaa
   102601 tggaaccgtc tggacgaaga cgagcagtat cgtggtcgtt atcaaatctc tgttaagccg
   102661 cagggttatc agcaggcggt tacggttaaa ctgctgaacc tggaacaggc gggcaaaccg
   102721 gttgcagacg cggcttccat gcagcgttac agcacggaga tgatgaacgt tatttccgcc
   102781 ggtctggata aatctgccac tgacgccgcg aacgctgcgc aaaatcgtgc ctccaccact
   102841 atggacgtac aaagtgcagc tgatgacacc ggtttaccaa tgctggtcgt acgcgggccg
   102901 ttcaatgtgg tttggcaacg tctgccagcg gcgctggaaa aagtgggcat gaaagtgacc
   102961 gacagcaccc gttcgcaggg caacatggcc gtaacttata agccgctgtc tgacagcgac
   103021 tggcaggaac tgggcgcgag cgatccaggc ctggcatccg gtgactataa actgcaggtt
   103081 ggcgatttag ataaccgcag cagcctacag ttcatcgatc cgaaaggtca tactctgact
   103141 cagagtcaga acgacgcgct ggtagctgtc ttccaggctg cgtttagcaa gtaaaaatac
   103201 agggctggaa tcatccggcc cttttttctg atatgatacg caaacgtgtg cgtcggcagg
   103261 aaaacgcgat tttagcggta attcgcacga aatttgtttg tcggacgtag ttcggataag
   103321 gcgttcacgc cgcatccgac aaaacatccg gcacaccaga cagcaaaaga ttttaaaacg
   103381 ttaattcaca cccaggagtg ataaagatgc aaaagcaagc tgagttgtat cgtggtaaag
   103441 cgaaaaccgt atacagcacg gaaaacccgg acctgttggt gctcgaattc cgcaatgata
   103501 cgtcagcagg ggatggcgcg cgcattgagc agtttgatcg caaaggtatg gtgaacaaca
   103561 agttcaatta cttcattatg agcaaactgg ctgaagcggg tatcccgact caaatggagc
   103621 gtctgctctc cgataccgaa tgtctggtga aaaagctgga tatggtgccg gttgagtgtg
   103681 tcgtgcgtaa ccgtgctgct ggctctctgg tgaaacgtct tggaatcgaa gaaggtattg
   103741 agctgaaccc gccgctgttc gatctgttcc tgaaaaacga cgccatgcac gatccgatgg
   103801 tcaacgaatc ttactgcgaa acctttggct gggtgagcaa agagaacctg gcgcgtatga
   103861 aagagctgac ctacaaagcg aacgacgtgc tgaaaaaact gttcgatgat gctggtctga
   103921 ttctggtcga cttcaagctg gagtttggcc tgtacaaagg tgaagtggta ctgggcgatg
   103981 agttctcccc ggacggcagc cgcctgtggg acaaagaaac actggagaaa atggacaaag
   104041 accgtttccg ccagagcctc ggtggcctga tcgaagccta tgaagccgtc gcccgccgcc
   104101 tgggtgtaca gctggactga tttttctggt tgcttgtttc tttagccgga gggtactccg
   104161 gctaaatgtc tttgataccc ccgctacaat acttctcatt atctcccttt gacaggaaag
   104221 tcataccagg ccaatatgta tatacataac gtatatccca aaaagggggg ggctatggaa
   104281 actactgtat ttttaagtaa tcgcagtcag gccgtcagat taccgaaagc ggtcgctctg
   104341 ccagaagacg ttaagaaagt agaaattatt gcgattggtc gtacaagaat catcactccc
   104401 gccggtgagt cctgggacag ttggtttgat ggcgaaaatg tgagtgcgga ttttatggat
   104461 atccgtgatc aacccgcaat gcaggaaagg gaatcatttt gatgctgaaa ttcatgctgg
   104521 ataccaatat ctgtattttc actattaaga ataaaccagt acatgtcaga gagcggttta
   104581 acctgaattc tggccggatg tgtataagtt ctgtaacatt gatggagctt atctatgggg
   104641 cagaaaaaag tcagatgcca gaacgcaatt tggcggttat tgaaggtttc gtatctcgtt
   104701 tggtagtgct tgattatgat agtgctgctg cgacgcatac cgggcaaatc agggccgagc
   104761 ttgcccggca gggaaggcct gttggacctt ttgaccagat gatagcggga catgctcgca
   104821 gtcgcggttt gattgtggtt accaacaata cccgagagtt tgagcgagtg gcgggaatca
   104881 gactagaaga ctggagctaa cattctcttt tacttctaac attcgtaaat tatataacgt
   104941 ggcatgaagc cttaattcct ccgccatttc atcccgcttt cctgtggtaa tcttcctctg
   105001 aaccacctac gatcatttct ataatgaata tattgttgag gtatctatgc gttggcaagg
   105061 gcgacgtgaa agtgacaatg ttgaagacag gcgcaacagc tccggtggtc cgtctatggg
   105121 cggtcccggt tttcgcctgc caagcggtaa aggcgggctg attttactgt tagtcgtgct
   105181 ggttgcaggc tactatggtg ttgatttaac cgggttaatg actggacagc cggtttccca
   105241 acaacaatca acgcggtcca ttagccctaa tgaagacgaa gctgcaaaat tcacctcggt
   105301 gattctggca accacggaag acacctgggg acaacagttc gagaagatgg gtaagaccta
   105361 tcagcaaccg aagctggtca tgtaccgtgg aatgacgcgc accggctgcg gggctggtca
   105421 gtccattatg gggccgttct attgcccggc ggatggcaca gtttatatcg atctctcctt
   105481 ctatgatgac atgaaagaca aacttggcgc ggatggcgat tttgcccagg ggtacgttat
   105541 cgcccatgaa gtcggtcatc atgtgcagaa actgttaggc atcgagccga aagttcgtca
   105601 actgcaacaa aacgcgacgc aggcggaagt gaaccgctta tctgtgcgta tggaactcca
   105661 ggccgactgt tttgccggtg tctgggggca tagtatgcag cagcaaggcg ttctggaaac
   105721 cggcgatctg gaagaggcgc tgaacgcggc gcaggccatc ggcgatgacc gtttacaaca
   105781 gcaaagtcag gggcgagtag taccagatag tttcacacat ggcacttctc agcaacgcta
   105841 cagctggttt aaacgtggtt tcgacagcgg cgatccggca caatgcaata cttttggtaa
   105901 aagcatttaa cttccggggc agggatggct gaactgactg cgcttcacac attaacagcg
   105961 caaatgaaac gtgaagggat ccgccgcttg ctggtgttga gcggggaaga gggttggtgt
   106021 tttgatcatg cgcttaagtt gcgtgatgcc ttacctggcg actggctgtg gatttcgccg
   106081 cagccagatg ctgaaaacca ctgttcaccc tcggcgctac aaactttact tgggcgcgag
   106141 ttccggcatg cggtattcga cgcccgccac ggctttgatg ccgctgcctt tgcagcactt
   106201 agcggaacgt tgaaagcggg aagctggctg gttttgttac tccctgtatg ggaagagtgg
   106261 gaaaaccaac ctgatgccga ttcgctgcgc tggagtgatt gccctgaccc tattgcgacg
   106321 ccgcattttg tccagcatct caaacgcgta cttacggcgg ataacgatgc tatcctctgg
   106381 cggcaaaacc agccgttctc gttggcgcat tttactcccc gtactgactg gcaccccgcg
   106441 accggcgcac cacaaccaga acaacagcaa ctcttacagc agctactgac catgcctccg
   106501 ggcgtggcag cggtaacggc tgcgcgtggg cgcggtaagt cggcgttggc agggcaactc
   106561 atttctcgta ttgcgggcag tgcgattgtc accgcgcccg caaaagcggc aacggatgta
   106621 ctggcacaat ttgcgggcga gaagtttcgc tttattgcac cggatgcctt gttagccagc
   106681 gatgagcaag ccgactggct ggtggtcgac gaagccgcag ccatacctgc gccgttgttg
   106741 catcaactgg tatcgcgttt tcctcgaacg ttgttaacca ctacggtgca gggctacgaa
   106801 ggcaccggac gtggtttttt gctgaaattt tgcgctcgct ttccgcattt acaccgtttt
   106861 gaactgcaac agccgatccg ctgggcacag ggatgcccgc tggaaaaaat ggttagtgag
   106921 gcactggttt ttgacgatga aaacttcacc catacaccac aaggcaatat cgtcatttcc
   106981 gcatttgaac aaacgttatg gcgaagcgag ccagaaacgc cgttaaaggt ttatcagtta
   107041 ttgtctggtg cgcactaccg gacttcgccg ctggatttac gccggatgat ggatgcacca
   107101 gggcaacatt ttttacaggc ggctggcgaa aacgagattg ccggagcgct gtggctggtg
   107161 gatgaggggg gattatctca acaactcagt caggcggtat gggcaggttt tcgtcgcccg
   107221 cggggtaatc tggtggccca gtcgctggcg gcgcacggta gcaatccact ggcagcgaca
   107281 ttgcgtggac ggcgggtcag ccggatagca gttcatccgg cgcgtcagcg ggaaggcaca
   107341 gggcagcaac ttattgctgg tgctttgcaa tatacgcgtg acctcgacta tctttcggtg
   107401 agttttggtt acaccgggga gttatggcgt ttctggcacc gctgcggttt tgtgctggtg
   107461 cggatgggta atcatcgtga agccagcagc ggttgctata cggcgatggc gctgttaccg
   107521 atgagtaatg cgggtaaaca actggctgaa cgtgagcatt accgtttacg tcgcgatgcg
   107581 caagctctcg caaagtggaa tggcgaaacg cttcctgttg atccactaaa cgatgccgtc
   107641 ctttctgacg acgactggct tgaactggcc ggttttgctt tcgctcatcg tccgctatta
   107701 acatcgttag gttgcttatt gcgtctgcta caaaccagtg aactggcatt accggcgctg
   107761 cgtgggcgtt tacagaaaaa cgtcagcgac gcgcagttat gtaccacact taaactttca
   107821 ggccgcaaga tgttactggt ccgtcagcgg gaagaggccg cgcaggcgct gttcgcactt
   107881 aatgatgttc gcactgagcg tctgcgcgat cgcataacgc aatggcaatt ttttcactga
   107941 ctccttcaat tttctcccat ggtcattgtg agtcagcggc gtaaaattaa tgacatcagt
   108001 taaggagttc gccatgaaac atgaccattt tgttgttcaa agcccggata aacctgcgca
   108061 acagttgtta ctgcttttcc acggtgtcgg ggataacccg gtggcaatgg gggaaatagg
   108121 tagctggttt gcaccgctgt ttcctgatgc gctggtggtg agtgtcggtg gcgcggagcc
   108181 gagcggtaat ccggcggggc gtcagtggtt ttcagtgcag ggtattacgg aagataatcg
   108241 ccaggcgcgt gtggatgcca tcatgccgac gtttattgaa acggtacgct actggcagaa
   108301 acagagcgga gtaggggcta acgccacggc gctaattggt ttctcacaag gcgcgattat
   108361 ggcgctggag agcattaaag ccgaaccggg ccttgcttcg cgcgtcattg cctttaacgg
   108421 acgctatgcg agcctgccgg agaccgcgtc tacagccacg acaattcact tgattcatgg
   108481 tggtgaagat ccggttatcg atctggcgca tgcagttgcg gcgcaggaag cgttaatcag
   108541 tgccggtggt gacgtgacgc tggatatcgt ggaggattta ggccatgcga tcgacaatcg
   108601 cagtatgcaa tttgccctgg atcacttgcg ttataccatt ccgaaacatt atttcgacga
   108661 agcgctaagt ggcggtaagc ctggcgatga tgatgtgatt gaaatgatgt aaaagacaga
   108721 ttacctggcc tgataagacg cgtgagcgtc gcatcaggca tcgttcacca ttgccggatg
   108781 tggcgttaac gccttatccg gcctacggtt gagcactcag cttacttctt cggttgatcc
   108841 tttttcggcc agtcgtcgtc atcgtcccac ttatcgttga aatcacgatg cgggggaagc
   108901 tccggcttgt tggcgagaaa tttcttgtgg tcgacgcgct tgagatcttt aatcacgttc
   108961 agcaggacgc ctaccaaaaa gacaatcacc agaatccacc aatatttagc cagccagtcc
   109021 atgcttattt cctcttgcag aaccactcat caggcgacga gctgttccat gatacgttga
   109081 tacatacggg caagtagctg caggtcggca gcgttcacac attcattaat tttatgaata
   109141 gtggcattga ccggcccgag ttccaccacc tgcgccccca tgcgagcaat aaagcgcccg
   109201 tcggacgttc cgcctgtggt cagtagctgc ggtttaattt cattatagtg ctcaaccgcg
   109261 ttaacgaccg catccaccag tttaccgcgc gcggtcaaaa atggctgccc ggaaagccac
   109321 cagtccaccg tataacgcag ttgatgtttt tcaagcaggg caagcacctg tgctttgatc
   109381 atctcatcag tcagttcggt gctgaagcgg aagttaaact gcacaaacag ttcacccgga
   109441 ataacattgt tactgcccgt tcccgcctga atattagcaa tctgcatact ggtcgccggg
   109501 aaaaattcat tgccctgatc ccactcaata gccactaatt cattaaggaa aggtgctgcg
   109561 cgatgtactg gattgtcagc cagatgcggg taggccacat gcccctgaac gccatgaatg
   109621 gtaaggttgc aggttaacga tccgcgacga ccatttttca ccacatcacc aaccacttcg
   109681 atactcgacg gttcgccgac caggcagtaa tcgagacgct cattacgtgc catcaacgct
   109741 tcgacgactt ttaccgtacc gttgtgggca ctggcttctt catcagaggt gatcagaaat
   109801 gccagtcgcc ccgtatggtt gggatgttgt gcgacaaagc gttctgccgc taccaccatc
   109861 gccgccagcg agcctttcat atctgccgca ccgcgtccga ataacatgcc atcacgaatg
   109921 gtgggttcaa acggcggatt gatccaacga tcggcgtcgc caggcggcac cacgtcggta
   109981 tgcccggcaa aggctaacgt ttcaccttgc ccacgccatg cccaaaaatt ctgcgtatcg
   110041 gcaaagtcca tgcgttcaac ggtaaaaccg atcgcctgca aacgttcaat caacaaagcc
   110101 tggcatcctg cgtcatcagg actcagggaa gggcggcgaa taagctgttg tgtcagctca
   110161 ataaccgggc acgacataga ctacacctca tggaaaaatt gctgataact ggaatcactg
   110221 aaacccagca gcataggctt accaggcgcg cagagcaatg gacgtttgat aattgcaggc
   110281 atttcagtca ttaatgccgc cgcagaggcc gcatcggtga ttttattgcg ggtggtttcg
   110341 tccagtttac gccaggttgt accacgggtg ttcagtaacg cttcccagcc taattcgttg
   110401 ataaaaccgt tcaataattc gctgtccagc ccatcgacgc ggtaatcatg aaaacgatag
   110461 tcgatgttat tggcttccag ccaacggcga gcctttttaa tggtgtcaca atttttgatg
   110521 ccgtaaagtg taaccataat gaatcctttt tcgatttatg agaataaata ctcatttaag
   110581 ggtgaaaaca ttttgcctgc aaatgattat caggaaatat aacattatcg aagtattcaa
   110641 attaacaact attaaataat attaaacatt tttaacgtaa acattaagaa tattcatctt
   110701 gttatctgtc tgtattttaa ccagaattaa atcagtatta gatgccgtat gaatatctcg
   110761 aaatgttgct gtgtatcaca tacaaattat caccgcagga ccatagtatt tacataaggt
   110821 ttgtcccccg gaggtagtca tcgcagcaat cgagtaaatt agcttcacca cggtatattg
   110881 tttccgtaga atacccataa ttataagaga ggttgttatg attgaacgtg aactggggaa
   110941 ctggaaagac tttatcgaag ttatgcttcg taagtaattc ccgagacaaa gtataaacag
   111001 caagaacccg ctgagcaggt tcttaatcgg aaagttgaaa aaggcgacac attggcatgt
   111061 cgcctttttt attgcttatt ccgggcgcgg cttcagcggg aagcggcggc gcaccagcac
   111121 aaagaacagc ggcacgaagt aaatagccag aatagtagct gaaatcatcc cgcccattac
   111181 gccagtaccc accgcatgct gaccaccgga accggcaccc gtgctggttg ccattggcaa
   111241 tacgccgaag ataaatgcca gcgaggtcat cagaatcggg cgtaaacgct gacggcaggc
   111301 gtggagcgtc gcttcaaaca ggtcgtggcc tttttggttc atctcgttag caaactcgac
   111361 gatcaggatg gcgtttttcg ccgataaacc aatgaccgtt aacaggccca cctggaagta
   111421 aacgtcgttt tccagcccgc gcatccaggt tgccagcagc gcgccgataa cccccagcgg
   111481 cacgaccagc attaccgaga acggtaccga ccagctttca tacaatgccg ccagacacag
   111541 gaatactacc agcaaggaaa tggcgtacag cgccggagcc tgcgcgccgg aaagccgctc
   111601 ctgatacgac atcgccgtcc actccagacc aaagccgttt ggcaactgct tcactaacga
   111661 ttccataata tccatcgccg taccggtact gacccccggt gcggcttccc caacaatctc
   111721 aaccgcagaa taaccgttat agcgttccag acgcggcgag cctgtctccc agcgtgaggt
   111781 cgcgaaagca gagaagggca ccatgccgcc atctttattt cggacatacc agagattaat
   111841 gtcatctggc agcatgcgat acggcgcagc tgcctgcaca tagactttct tcacgcgacc
   111901 gcgatccata aagtcattca catagctcga accccaggcg gtttgcagtg tgtcgttaat
   111961 atcgtcgata gcaacgccca gcgcctgagc tttacgctgg tcgatatcaa tctgcaactg
   112021 cggactgtca tcgaggccgt tatggcgcac acgggttagc tccgggtttt ccgccgccag
   112081 cgccagcaac tggttacgtg ctgccatcag cgcatcgtga cctgctccag cgtggtcctg
   112141 caactccata tcaaaacctg cagaactacc aagaccgcta attgctggcg ggctgctggc
   112201 gataacgcga gcttctttaa tcttgttaaa cgccttcgtt gcacgctcga taatggcaaa
   112261 tgaggtgccg gtcttactgt cgcgttcgct ccagtctttc aggcggataa acattcgcgc
   112321 cacgttttgc ccgttacccc cggggccaga accaacagtg gcaaacaccg acatgatgtt
   112381 gtctttttca tgggtgaagt aatatttctc gatttgctca acgactttca gggtctgttg
   112441 ttgggttgaa ccgctgggca attgtaccga ggtagtaaac atgccacggt cttccagcgg
   112501 taagaacgac gtcggcaaac gcaggaacag gaacaccatg ccgccaagca gcaggacata
   112561 aatcacaatc cagcgcaggc tacggtggag aattttcgcc accccttttt cgtagcgttc
   112621 ggcgttgcgg ttaaacatct ggttaaacca ggcaaaaaag cctttttgcc cgtgatgctc
   112681 accttttttc agtggcttaa gtagtgtggc acacagagcc ggagtgagga tcatcgctac
   112741 cagtactgac agcaccatcg ccgcaacaat ggtaatagag aactggcgat agatggcacc
   112801 ggtggtgccg ccgaagaagg ccattggtac aaataccgcc gaaagaacca tcgcaatccc
   112861 gaccagtgcc ccctggatct gccccatcga tttacgtgtg gcttcgcgag gagtgagtcc
   112921 ttcctcactc ataatacgtt cgacgttttc caccaccacg attgcgtcat ccaccagcag
   112981 accgatcgcc agcaccatcg cgaacatggt taaggtgttg acgctgtaac cgaaggcgta
   113041 aagtacggag aaggttccca tcaacaccac cggcacggcg atagtgggta tcagcgtggc
   113101 gcggaagttt tgcaggaaca gatacataac gaggaaaacc agagcgatag cttccagcag
   113161 cgttttcacc acgtcttcaa tggaggcttt aacaaacgag gtggtttcat acgccacctt
   113221 gtattccagt ccgtgcggga aatactgcgc cagctcgtcg agacgattga gcaccagctc
   113281 cgctgtcgcc atttcgtttg cgccggaggc cagttttacc cccagcccgg aggctggctt
   113341 accattgaag cggctaagat aatcgtattt ctccgccccc atttcgacgg tggcgacatc
   113401 gcccagcctt acctctgagc cgtcttgatt caccctcaag gtgatatcgc ggaactgttc
   113461 tggtgtttgc agcagtgact gggcgttaat ggtggcgttg agcgcctgct tatcgacgga
   113521 aggtgtacca ccaagttgcc caaccgcaat ctgcgcgttc tgtgactcaa tggcatcagt
   113581 gacatcttta gccgtcatct ggaaactgtt gagtttcgcc gggtccagcc agatacgcat
   113641 ggaatattgc gaaccatagg catcgatatc cccgacgcca ttcacgcggc ttaacgggtc
   113701 ctgaatatta ctggcaacat aatcggcaat atcctgttta tccatcgaac catcggtaga
   113761 gacgaaagca atggtcagaa tattggtatc gccggtttta cgcaccgtca cgccctgatt
   113821 ttgcaccgcc tgcggtaact ttcgcatggc tgattgcagc tggttttgta cttgctgcac
   113881 ggcttcgtcc ggatcggtgc ctgctttaaa acttaaagtg acagatgcct gaccggtgcc
   113941 actgctctga gatgacatat acatgagatt atcgaggccg gtcatatttt gctcgataac
   114001 ctgggtcacg gtgttttcca gcgtctgggc cgatgcgccg ggatagttag cggtcactcg
   114061 cacattcggt ggcgcgagat cggggtattg ttcaacgggc aatgagaaaa tcgccagggt
   114121 acctgtcaga cacaacagga ttgccagcac ccaggcaaaa atggggcgat caataaagaa
   114181 attcgccatt aaaagaggac ctcgtgtttc tgcgtatcgt tgtaggcttg acttgcttca
   114241 ctgtagcggc aaggtacgag ccaatcgtgg agaaaaaaag gagttaatgt aaattatcat
   114301 gcccttttat actgaacctt aagtgcaagt attctttggt cagtaggagg cattacatca
   114361 gctgactttc ctcaccctcc gcggagcgaa agctaatact cactaacgtg ccgccgccgg
   114421 aaggttgtga aaaagtcagc gtcccaccca gccgttccgc gcgttcgcgc atgatattca
   114481 gaccataatg accttcgggc tctttcggtt caccgatgcc aatcccgtta tcacggatat
   114541 aaaccgtgtg attgccgtcc ggcgcggtga cgcaactgac ggcgatttcg ctggcgttgg
   114601 cgtgcttcat cgcattcagc accgcttcgc gaataatttg caacaaatgc acctgcattt
   114661 gcgcatccag cgccagggtt ggcagacggc agtcgagggt cagtttggcg ctggtttgat
   114721 tttgtaacgt atccagcatt tccctcaacg cggaggggag atccgcctgc tgcagcgtca
   114781 ggcggaaagt agtcaacagc tcgcgtaact gccgataagc atcattcaac gcctgggaaa
   114841 aatcggccat gatactttgt gcggtggcgt tatcttccgg tatcgaacgc ttcagtaacg
   114901 tcaactggat acgtaagtaa gaaagtacct gagccagcga gtcgtgcaat tcgcgggcga
   114961 tggttgcacg ttcttccatc aacaataact gctgaaaatg cttctgcgcc tgattaaagt
   115021 acaaaccgcg tcccagcatc gacgaaacgc tgttaagcag cggttctgat gatgaaacgt
   115081 gactattttg ccagtgcagt tcgccgtaaa ccgtctcttg cattgtcacc ggtaaaatct
   115141 gcatcggcaa ttccgggttt ggttgccctt cgctaatccg ccagttttca ccgacattta
   115201 actccagata ttcagccgct tcattgtcgc gaacaatctg caaaatatgg cggaaacaat
   115261 gcacatcaat ctggctggtg ttcagcgcct gggaacattg atacaacacc tccagacgac
   115321 gcttggcctc gtggagatcg cgggtctttt cttctactga cgcctccagc gaaaggtaca
   115381 atttatgcag ctcgctcgac atctggttaa aggtttttgc aagcagacca agctcattcg
   115441 gcagactggt atccagcggc ggcgagtcga actgcccgtg ttcaatacgt tgactggcgg
   115501 taaccagctg attcagcggg gcaaccacct gatggcgtat acggcgcaaa gtaaaaaaga
   115561 ccagcgtgaa aataccgata ccgccagcca gggaaatcgc caccaccagc agcattttgc
   115621 gttcagcgta gtgctgtaaa gccagcacga acaggtctat ctgattaaca taattattaa
   115681 tattggcctg ataccacggc aaatcgccct tgctgagccg attattcatc tccagccagt
   115741 tggcattcag atgcgcatag cgagttttta ctgcttctgg cacataccag acgttgagat
   115801 tggttaatac cggtgaatgc agtgcctgct gaaacaactg gcgatgtgca ttgagttgtg
   115861 gactgccact ttgcaagtcg tagcccaggc ggtaactctg catacgtagc gatccggcaa
   115921 tattgatagc ctcagcgtcg cgcaaactgc tcgccagagt tagcagagcg atacccgtgg
   115981 aaagaatcga cagcagcaca atgtaaaaaa aggcccgggc cagactggcc gagacgggtc
   116041 gtttaacaat cacacgcgtc ttctccacaa aaaatcatta atgttccagt tagctgaaac
   116101 acaatttagt cagtgatggg attatttgat ctgccacagt ttatagcgaa atagttactt
   116161 attctgggca catgaacatt gccgattccc ctgtaagtcg ggtaataaca acactcatat
   116221 aaagaataag gtttttacaa ccaaaaaaga aggtcgttat gaatcgtttt attatggcca
   116281 acagtcagca atgtctgggt tgtcatgctt gtgaaatcgc ctgtgtcatg gctcacaatg
   116341 atgagcaaca tgtcctgagc caacaccatt ttcatccccg aattacggtt atcaaacatc
   116401 aacagcaacg tagtgcagtg acctgtcacc attgtgaaga tgcgccctgc gcccgtagct
   116461 gccctaatgg cgcaatcagc cacgttgatg acagcattca ggtcaatcag caaaagtgta
   116521 ttggctgtaa atcctgcgtg gtggcctgtc cttttggtac gatgcaaatc gtcctgacac
   116581 ccgtcgcggc aggaaaagta aaagccacgg cgcataaatg cgacctttgt gcggggcgcg
   116641 aaaacggtcc tgcctgtgtt gagaattgcc cggcggacgc gctgcaactg gtcactgacg
   116701 tcgcactctc cggcatggcg aaatcccgcc gcttgcgcac cgcgcgtcag gaacatcaac
   116761 cgtggcatgc cagtaccgcg gcgcaagaaa tgccggtaat gagtaaagtc gaacaaatgc
   116821 aggcaacgcc cgcgcgtggc gagccggata aactggcgat tgaagcgcgc aaaaccggtt
   116881 ttgatgaaat ttatctgcca tttcgcgccg accaggcaca acgggaagcc tcgcgctgcc
   116941 ttaagtgcgg cgagcacagc gtttgtgaat ggacctgccc gctgcataac catattccgc
   117001 agtggattga actggtgaaa gccggaaaca tcgacgccgc cgtcgagctt tctcaccaga
   117061 ccaacaccct gccggaaatt accggacgcg tttgtccgca agaccgtttg tgtgaaggtg
   117121 cctgtactat tcgcgatgag cacggtgctg taactatcgg caacattgaa cgctatattt
   117181 cagatcaggc gttggcgaaa ggttggcgtc ctgacttaag tcatgtcacc aaagtggaca
   117241 agcgggtggc gattatcggg gcaggcccgg cagggctggc ctgtgcggat gttctgaccc
   117301 gcaatggcgt ggcggtgacg gtgtacgatc gccatccaga aattggtggc ttgctcactt
   117361 tcggcattcc ttctttcaaa ctggataaat ccctgctggc acgccgtcgg gaaatcttca
   117421 gcgcgatggg gattcacttc gaactcaatt gtgaagtggg taaagatgtc tctttggatt
   117481 cgcttttgga acaatacgac gcggtcttcg ttggcgtagg cacttaccgt tccatgaaag
   117541 cgggtttacc caatgaagat gcgccgggcg tttatgacgc gctgccgttc ctcattgcca
   117601 acactaaaca ggtgatgggg ctcgaagagc taccggaaga gccgtttatc aataccgccg
   117661 gacttaacgt cgtggtactg ggcggcggcg acaccgcgat ggactgtgtg cgtactgcgc
   117721 tgcgccacgg cgcgagtaac gtcacctgcg cttatcgtcg tgatgaagct aacatgccag
   117781 gctcgaagaa agaggtgaag aacgcccgcg aagagggggc caacttcgaa tttaacgtcc
   117841 agccggtggc gcttgagctg aatgaacaag gtcacgtttg cggaattcgt ttcctgcgca
   117901 cgcgtcttgg cgagccggat gcccaggggc gtcggcgacc tgtaccgatt gagggcagtg
   117961 aatttgtcat gccagccgat gcggtgatta tggcgtttgg cttcaatcca cacgggatgc
   118021 cgtggctgga gtcgcacggt gtaacggtag acaaatgggg ccgcatcatc gcggatgtgg
   118081 aaagccagta ccgttaccag accaccaatc cgaaaatctt cgccggtggc gacgccgtgc
   118141 gtggtgcgga tctggtggtt accgcaatgg cagaaggacg tcatgcggca caggggatta
   118201 ttgactggct gggggtaaaa tcagtcaaat ctcactgata gcctgcgcag acaaacccga
   118261 cttcacagcg taagataatt gttcatttcg cgctgtggag tcggtatgac gcaacaaatc
   118321 accctcatta aagacaaaat tctctccgat aactatttca ccctgcacaa cattacctac
   118381 gatctcacgc gcaaagatgg cgaagttatc cgccataaac gtgaagttta cgatcgcggt
   118441 aatggtgcga cgatcctcct gtacaacgcg aagaaaaaga gcgtggttct gattcgtcag
   118501 ttccgtgtcg ctacctgggt taatggcaat gaaagcgggc agctgattga aacctgcgcc
   118561 gggctgctgg ataacgacga accggaagta tgcattcgta aagaagcgat tgaagagacg
   118621 ggctatgaag tgggcgaagt gcgcaaatta tttgaactgt atatgtcgcc tggcggtgtg
   118681 actgagctaa tccacttttt tatcgccgaa tacagtgaca atcagcgcgc taacgccggt
   118741 ggcggtgttg aagatgaaga tattgaagtg ctcgagctgc cgttcagcca ggcgctggag
   118801 atgatcaaaa ccggcgagat acgtgacggt aagacggtgt tattgcttaa ctatttgcaa
   118861 acgtcacatt taatggactg aaaaataaca ataatatttc gttgtttatt attggctcaa
   118921 tccgacaaat ctgattgagc cgcgctacct gcgcaacgaa gatacgactt gtgctgtttg
   118981 tttgaacttc tggggtcgta ccgtccatgc gctatcgcat tttccttctc ttttttttcg
   119041 ctttgttgcc gacgtctttg gtgtgggcgg caccagcgca acgggcgttt tccgactggc
   119101 aggtcacctg taataaccaa aacttctgcg tggcgcgcaa tacgggcgat cataatggac
   119161 tggtgatgac cctgagccgc agcgccgggg cgcataccga tgccgtttta cgtattgagc
   119221 gcggcgggtt gaagtcgccg gatgcgtctg aaggagagat agcgccacgg ctgctgttag
   119281 atggtgagcc gttggcgtta agtggtgaca agtggcggat ttcaccatgg ttattagtaa
   119341 ccgatgatac ggcaaccatc accgcgtttt tgcagatgat tcaggaaggg aaggcgatca
   119401 ccttacgcga cggcaatcag accatttctc tgagtggctt aaaagcggcg ttgttgttta
   119461 ttgatgctca gcaaaagcgc gttggcagtg aaaccgcgtg gatcaagaaa ggggacgaac
   119521 cgccgctcag cgtaccgccc gcgcctgcgc tgaaagaggt cgcggtggtt aacccaacgc
   119581 cgacgccact ctcactcgaa gaacgcaacg atttgctgga ttatggaaac tggcggatga
   119641 atggtctgcg ctgctcgctt gatccgttac gtcgtgaggt gaatgtcact gcgctgactg
   119701 atgataaagc gctgatgatg attagctgtg aggcaggggc ctataacacc attgatttgg
   119761 catggattgt gtcgcgtaaa aagccactag cctcgcgccc ggttcggttg cgtttgccat
   119821 tcaacaacgg tcaggagacg aatgaactgg aactgatgaa cgcaacattt gatgagaaat
   119881 cgcgtgaact ggtgacctta gcgaaagggc gcggattaag cgattgtggc attcaggcgc
   119941 gctggcgctt tgacggtcag cgttttcgcc tggtgcgtta tgccgcagaa cccacctgcg
   120001 ataactggca tgggccagac gcctggccca cgttgtggat cacccgttaa acaaaattgc
   120061 ggggacatgt aggccggata agacgctgta ggccggataa gacgcgtcag cgtcgcatcc
   120121 ggcaatcagc atccggcgat caccatcagg cacctttcac tcccagcacc ttatgcgctt
   120181 ttgccacaat attctcggcg gtaaagccaa agaacgggaa cagcttatcc gccggagcag
   120241 attccccgta acccgtcatc ccgacaattg cccctttcag accaacatac ttgtaccagt
   120301 aatcggcaat acctgcttcc accgccacgc gagccgcaac gttagaaggc aacaccgact
   120361 cccgatattc ctcatcctgg gcgtcgaaaa tatcggtcga gggcagggaa actacgcgta
   120421 cattgcgacc ttctcccgct aatttctctg ccgcttgcag ggtgatttcc atctctgaac
   120481 cggtggcaat cagaataata tctggcttac cgccgctgtc tttcagcaca taaccgccac
   120541 gagcaatctc tttaacctga tccggcgtac gttccacctg ggccagattc tgccttgaga
   120601 ggatcagtgc tgtcggcccg ttgtggcgct caaccgccag cttccagccc accgccgctt
   120661 ccacctgatc gcacggtcgc caggtgctga aattcggcgt taagcgcaga ctggccagtt
   120721 gctcaacggc ctggtgcgtc ggaccatctt cccctaagcc aatagaatcg tgggtataaa
   120781 ccataatctg ccgtgctttc atcagtgccg ccatccgcgc ggcattacgg gcgtattcaa
   120841 caaacatcag gaacgtcgcg gtatacggca caaagccgcc gtggtgcgca atgccgttgg
   120901 cgatagcggt catgccaaat tcacgcaccc cgtagtgaat gtagttgccc gccggatctt
   120961 ccttcagcga cacagagcct ttccagatgg tgaggttgct gggagccaga tccgctgaac
   121021 ctccgagcag ctccggtagc atcggtccgt aagcgttaag cgtattttgc gaagccttac
   121081 gggtggcgat tttcgccgga ttcgcctgca actcattgat atatttctga gtcgttttct
   121141 cccagtcctt cggtaaacca ccgctcatcc gacgggtaaa ctcttctgcc agttgcggat
   121201 gagccttttt ataggcggca aacttctcat tccagctctg ctgcgctttt tcgccttttt
   121261 cgcgggcatc ccaggcgtga taaatctctt tagggatctc aaatggcgga tggtgccagc
   121321 ccagtttttg ccgtgccagc gccacttctt cttcccccag aggtgcgccg tgcgcctctt
   121381 ccttacctgc tttattcggc gaaccaaagc caatcaccgt acggcagata atcagcgacg
   121441 gcttatcttt cacgctttgc gcttcaagga tcgcttcctt caccgcctgc ggatcgtgac
   121501 cgtcgatttc atggatcaca tgccagtgat aggcttcaaa acgttttgcc gtatcgtcgg
   121561 taaaccagcc ttctgtttca ccgtcgatgg aaataccgtt gtgatcgtaa aaaccaatca
   121621 gcttgcccag tcccagcgtg cccgccagcg aacagacttc gtgggaaata ccttccatca
   121681 ggcagccgtc gcccataaac acataggtga agtgatcgac aatttcatga tccggctgat
   121741 taaactgcgc cgccagtgta cgctctgcta tcgccagtcc gacggcgttc gccaaacctt
   121801 gtccaagcgg accggtggtg gtttcaacac ctggcgtata gccaatctcc gggtggcctg
   121861 gggttttcga atgcaactga cggaagttct tcagttcttc cagcggcagg tcgtaaccgg
   121921 tcagatgtag caaactgtag agcagcatcg acgcgtgacc gttggaaaga ataaagcggt
   121981 cgcgatcata ccaggttggg tcggtaggat tatgtttaag aaaatcgttc cacagcactt
   122041 cggcaatatc agccatgccc atcggcgcgc cgggatgacc agaattggct ttttgtacag
   122101 catccatact gagtgcgcga atcgcattgg caaggtcttt tcgggacata taacactccg
   122161 tggctggttt atagtttggc ggcaagaaga tcttccagtt tgcgttgatc aacagcgaac
   122221 agacgaatgc cttcagacag tttttctacc gccatcgcat cctgattgtg ctcccaacgg
   122281 aactccgctt cgctcatggg agctgggcgt gggaacgtct gagaaggtgg gattaattta
   122341 cgtaccactg gcgaaacttt ttcctgcagc tccttcagca aattcggtgc gatagtcagt
   122401 cgatcgcagc cggttaaggc gaggatttgt tcggtgcgac ggaagctcgc gcccatcaca
   122461 atggtttcat agtggtgttg cttatagtag tcgtagatat tgcgcaccga tttaacgccc
   122521 ggatcttctt ccaccacata cgggtccatc ggcttgcgtg cctgatacca gtcataaata
   122581 cgcccgacaa acggcgaaat cagaaaaacg cccgcttctg cacaggcccg cgcctgggca
   122641 aaagaaaaca gcagcgtcag gttgcagtta ataccttctt tttccagctc ttcggccgcg
   122701 cgaattcctt cccaggtcga agccagtttg atcaaaatgc gtgatttctc aacgccttgt
   122761 tgctgataca agtccaccag atggcgcgcc ttctcaatac tcttttcttt atcaaaagag
   122821 aggcgtgcat caacttctgt tgacacgcga ccgggtacga ttttgagaat ttcagcaccg
   122881 aaattgactg ccagtttgtc acacgctgcg accacctgtt gttcctgggt cttgccattt
   122941 tttttacccc aggcgatagc atcgtctatt aaatgctcat attgtgataa tccggcagct
   123001 ttgagtaaca gcgaaggatt ggtggtggca tcctggggat gataatggcg aatggactca
   123061 atatcgccgc tgtctgccac gacagtggtg aactgtttga tgccgtctaa ctcgttcata
   123121 ggaaatactc cttgaaaagt aaagtgttag atgagtgcgt taattcacac ttctgagaaa
   123181 tttcgctaaa cgcatcaaaa aagcatagca gacaggcatg gtattgctgg attaagcagg
   123241 taacatcagt gttataggat tattaccaaa acattatatt aatggtgaga gtttggactt
   123301 gctcaaagtc tgtagactcc ggcagggtaa taatgtgcgc cacgttgtgg gcaggggctg
   123361 ttgcccacac actttatttg tgaacgttac gtgaaaggaa caaccaaatg gatgaccagt
   123421 taaaacaaag tgcacttgat ttccatgaat ttccagttcc agggaaaatc caggtttctc
   123481 caaccaagcc tctggcaacg cagcgcgatc tggcgctggc ctactcacca ggcgttgccg
   123541 caccttgtct tgaaatcgaa aaagacccgt taaaagccta caaatatacc gcgcgcggta
   123601 acctggtggc ggtgatctct aacggtacgg cggtgctggg gttaggcaac attggcgcgc
   123661 tggctggcaa accggtgatg gaaggcaagg gcgttctgtt taagaaattc gccgggattg
   123721 atgtatttga cattgaagtt gatgaactcg acccggacaa atttattgaa gttgtcgctg
   123781 cgctcgaacc gaccttcggc ggaatcaacc tcgaagacat taaagcgcca gaatgtttct
   123841 atattgaaca gaaactgcgc gagcggatga atattccggt attccacgac gatcagcacg
   123901 gcacggcaat catcagcact gccgccatcc tcaacggctt gcgcgtggtg gagaaaaaca
   123961 tctccgacgt gcggatggtg gtttccggcg cgggtgccgc agcaatcgcc tgtatgaacc
   124021 tgctggtagc gctgggtctg caaaaacata acatcgtggt ttgcgattca aaaggcgtta
   124081 tctatcaggg ccgtgagcca aacatggcgg aaaccaaagc cgcatatgcg gtggtggatg
   124141 acggcaaacg taccctcgat gatgtgattg aaggcgcgga tattttcctt ggatgttccg
   124201 gcccgaaagt gctgacccag gaaatggtga agaaaatggc tcgtgcgcca atgatcctgg
   124261 cgctggcgaa cccggaaccg gaaattctgc cgccgctggc gaaagaagtg cgtccggatg
   124321 ccatcatttg caccggtcgt tctgactatc caaaccaggt caacaacgtc ctttgcttcc
   124381 cgtttatctt ccgtggcgcg ctggatgttg gcgcaacggc tatcaatgaa gagatgaaac
   124441 tggcggcggt acgcgcgatt gcggaactgg cccacgccga acagagcgaa gtggtggctt
   124501 cagcgtatgg cgatcaggat ctgagctttg gtccggaata catcattcca aaaccgtttg
   124561 atccgcgctt gatcgttaag atcgctcctg cggtcgctaa agccgcgatg gagtcgggcg
   124621 tggcgacgcg tccgattgct gatttcgacg tctacatcga caagctgact gagttcgttt
   124681 acaaaaccaa cctgtttatg aagccgattt tctcccaggc tcgcaaagcg ccgaagcgcg
   124741 ttgttctgcc agaaggggaa gaggcgcgcg ttctgcatgc cactcaggaa ctggtaacgc
   124801 tgggactggc gaaaccgatc cttatcggtc gtccgaacgt gatcgaaatg cgcattcaga
   124861 aactgggctt gcagatcaaa gcgggcgttg attttgagat cgtcaataac gaatccgatc
   124921 cgcgctttaa agagtactgg accgaatact tccagatcat gaagcgtcgc ggtgtcactc
   124981 aggaacaggc gcagcgggcg ctgatcagta acccgacagt gatcggcgcg atcatggttc
   125041 agcgtgggga agccgatgca atgatctgcg gtacggtggg cgattatcat gaacatttta
   125101 gcgtggtgaa aaatgtcttt ggttatcgcg atggcgttca caccgcaggt gcaatgaacg
   125161 cgctgctgct gccgagtggt aacaccttta ttgccgatac ctacgtcaat gacgaaccag
   125221 acgcagaaga gctggcggag atcaccttga tggcggcaga aactgtccgt cgttttggta
   125281 ttgagccgcg cgttgctctg ttgtcgcact ccaactttgg ttcttctgac tgcccgtcgt
   125341 cgagcaaaat gcgtcaggcg ctggaactgg tcagggatcg tgcgccagat ctgatgattg
   125401 atggtgaaat gcacggcgat gcagcgctgg tggaagcgat tcgcaacgac cgtatgccgg
   125461 acagcccttt gaaaggttct gccaatattc tggtgatgcc gaacatggaa gctgcccgca
   125521 ttagttacaa cttactgcgc gtttccagct cggaaggtgt gactgtcggt ccggtgctga
   125581 tgggcgtggc gaaaccggtt cacgtgttaa cgccgatcgc atcggtgcgt cgtatcgtca
   125641 acatggtggc gctggccgtg gttgaagcgc aaacccaacc gctgtaattc ttttttaact
   125701 ctcacgctta ccctgaatat tcagggtaag cggtttggct gcaatatatt agtaaagctt
   125761 attactga
//
LOCUS       DAZUDJ010000005       123837 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.005, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000005 DAZUDJ010000000
VERSION     DAZUDJ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 123837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 123837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..123837
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.005"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(191..2605)
                     /gene="ybbP"
                     /locus_tag="ACHY1N_000484"
     CDS             complement(191..2605)
                     /gene="ybbP"
                     /locus_tag="ACHY1N_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease subunit YbbP"
                     /protein_id="HFS4042835.1"
                     /translation="MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLS
                     QQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGKQLTFATMTFAGDTPQLANVKAV
                     DDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
                     PDSGFNPFQMAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGSENQLDGYEKWLLPQLK
                     PEQRWYGLEQDEGALGRSMERSQQFLLLSALLTLLLAVAAVAVAMNHYCRSRYDLVAI
                     LKTLGAGRAQLRKLIVGQWLMVLLLSAVTGGAIGLLFENVLMVLLKPVLPAALPPASL
                     WPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNDVVANVWPLKFYLPIVSVVVVL
                     LLAGLMGGSMLLWAVLAGAVVLALLCGVLGWMLLNVLRRMTLKSLPLRLAVSRLLRQP
                     WSTLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIATEQVAPLKAF
                     LAEHQIVPESFYPVVRARLTAINDKPTEGNEDEALNRELNLTWQNTRPDHNPIVAGNW
                     PPKADEVSMEEGLAKRLNVALGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFP
                     EGALDGQPQSWLTSFRWENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTACGMLLLLAQVQVGMRQRHLELVVWRTLGAGKKLLRTTLWCEFAMLGFVSG
                     LVAAIGAETALAVLQAKVFDFPWEPDWRLWIVLPCSGALLLSLFGGWLGARLVKGKAL
                     FRQFAG"
     gene            complement(2602..3288)
                     /gene="ybbA"
                     /locus_tag="ACHY1N_000485"
     CDS             complement(2602..3288)
                     /gene="ybbA"
                     /locus_tag="ACHY1N_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter ATP-binding protein
                     YbbA"
                     /protein_id="HFS4042836.1"
                     /translation="MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGQPLHNMDEEARAKLRAKHVGFVFQSFMLIPT
                     LNALENVELPALLRGESSAESRNGAKALLEQLGLGKRLGHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLR
                     LVNGQLQEEA"
     gene            3259..3882
                     /gene="tesA"
                     /locus_tag="ACHY1N_000486"
     CDS             3259..3882
                     /gene="tesA"
                     /locus_tag="ACHY1N_000486"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016298 - lipase activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HFS4042837.1"
                     /translation="MNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSA
                     SAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLR
                     GFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS"
     gene            3872..4681
                     /gene="ybbO"
                     /locus_tag="ACHY1N_000487"
     CDS             3872..4681
                     /gene="ybbO"
                     /locus_tag="ACHY1N_000487"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HFS4042838.1"
                     /translation="MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLA
                     GCRKPDDVERMNNMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGP
                     LSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
                     ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARF
                     TLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMVLKRLLPGRVMDKILQG"
     gene            4742..5596
                     /gene="cnoX"
                     /locus_tag="ACHY1N_000488"
     CDS             4742..5596
                     /gene="cnoX"
                     /locus_tag="ACHY1N_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308582.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HFS4042839.1"
                     /translation="MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPI
                     LESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQEGNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
                     LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDAAL
                     ATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(5659..6438)
                     /gene="fetB"
                     /locus_tag="ACHY1N_000489"
     CDS             complement(5659..6438)
                     /gene="fetB"
                     /locus_tag="ACHY1N_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HFS4042840.1"
                     /translation="MNSHNITNESLALALMLVVVAILISHKEKLALEKDIFWSVGRAI
                     IQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWNAQKRSKYIAKAFISSFIAITVG
                     AGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
                     SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVTQLKKK"
     gene            complement(6425..7102)
                     /gene="fetA"
                     /locus_tag="ACHY1N_000490"
     CDS             complement(6425..7102)
                     /gene="fetA"
                     /locus_tag="ACHY1N_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HFS4042841.1"
                     /translation="MQENSPLLQLQNVGYLAGDAKILNNINFSLRAGEFKLITGPSGC
                     GKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLI
                     FPWQIRNQQPDPAIFLDFLERFALPDSILTKNIAELSGGEKQRISLIRNLQFMPKVLL
                     LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQ
                     EARYELA"
     gene            7248..8165
                     /gene="qmcA"
                     /locus_tag="ACHY1N_000491"
     CDS             7248..8165
                     /gene="qmcA"
                     /locus_tag="ACHY1N_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFS4042842.1"
                     /translation="MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVM
                     MPLEASSLMGSIAGIAELVKDSANKRTQP"
     gene            8162..8620
                     /gene="ybbJ"
                     /locus_tag="ACHY1N_000492"
     CDS             8162..8620
                     /gene="ybbJ"
                     /locus_tag="ACHY1N_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415021.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFS4042843.1"
                     /translation="MMELMVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     VVWLVPLGWEWQGVMFAILTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFV
                     LESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLHIRAVSS"
     gene            complement(8621..9028)
                     /gene="cueR"
                     /locus_tag="ACHY1N_000493"
     CDS             complement(8621..9028)
                     /gene="cueR"
                     /locus_tag="ACHY1N_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HFS4042844.1"
                     /translation="MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHL
                     NELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMR
                     DQLLALANACPGDDSADCPIIENLSGCCHHRAG"
     gene            complement(9025..9122)
                     /locus_tag="ACHY1N_000494"
                     /pseudo
     CDS             complement(9025..9122)
                     /locus_tag="ACHY1N_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308571.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9153..10445)
                     /gene="ybaT"
                     /locus_tag="ACHY1N_000495"
     CDS             complement(9153..10445)
                     /gene="ybaT"
                     /locus_tag="ACHY1N_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4042845.1"
                     /translation="MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEA
                     STWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTL
                     AVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
                     VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADK
                     VKDPQVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHV
                     GYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKSLWRQSTWGNIIVVV
                     LIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVI
                     VGFIYSLWSQGSRALIWIIGSLLLSLIVAMVMKRNKTV"
     gene            complement(10448..11380)
                     /gene="glsA"
                     /locus_tag="ACHY1N_000496"
     CDS             complement(10448..11380)
                     /gene="glsA"
                     /locus_tag="ACHY1N_000496"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFS4042846.1"
                     /translation="MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPSQLAAVA
                     IVTCDGNIYRAGDSDYRFALESISKVCTLALALEDVGPQAVQDKIGADPTGLPFNSVI
                     ALELHGGKPLSPLVNAGAIATTSLINAENVEQRWQRILHIQQQLAGEQVALSDEVNQS
                     EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLLNTVELATLGATLAAGGVN
                     PLTHERVLQADNVPYILAEMMMEGLYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGI
                     AAFSPPLDEEGNSVRGQKMVASVANQLGYNVFKG"
     gene            11642..14146
                     /gene="copA"
                     /locus_tag="ACHY1N_000497"
     CDS             11642..14146
                     /gene="copA"
                     /locus_tag="ACHY1N_000497"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HFS4042847.1"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVT
                     GTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQ
                     LLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
                     AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSL
                     WLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQW
                     FPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEK
                     SVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGESVHAGT
                     VVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALV
                     SAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDA
                     DALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADVDEAQALRLAAALEQGSSHPLAR
                     AILDKAGDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNEQQVGTKAIEAEITA
                     QASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANA
                     IAKEAGIDEVIAGVLPDGKAEAIKRLQSEGRQVAMVGDGINDAPALAQADVGIAMGGG
                     SDVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWP
                     FTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE"
     gene            complement(14361..14702)
                     /gene="ybaQ"
                     /locus_tag="ACHY1N_000498"
     CDS             complement(14361..14702)
                     /gene="ybaQ"
                     /locus_tag="ACHY1N_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antitoxin"
                     /protein_id="HFS4042848.1"
                     /translation="MKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSAL
                     INNNRKLTTEMAFRLAKVFDTTVDFRLNLQAAVDLWEVENNMRTQEELGRIETVAEYL
                     ARREERAKKVA"
     gene            14840..15634
                     /gene="ybaP"
                     /locus_tag="ACHY1N_000499"
     CDS             14840..15634
                     /gene="ybaP"
                     /locus_tag="ACHY1N_000499"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HFS4042849.1"
                     /translation="MDLLYRVKTLWAALRGNHYTWPAIDITLPGNRHFHLIGSIHMGS
                     HDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPTCEALEERINEEQLQNLQHIS
                     QEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
                     AENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNDITLPNTFSQ
                     SLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR"
     gene            15838..16317
                     /gene="ybaK"
                     /locus_tag="ACHY1N_000500"
     CDS             15838..16317
                     /gene="ybaK"
                     /locus_tag="ACHY1N_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HFS4042850.1"
                     /translation="MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQV
                     YKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGG
                     ISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAAGDLAKILDAKFADIARRD"
     gene            complement(16354..18006)
                     /gene="ushA"
                     /locus_tag="ACHY1N_000501"
     CDS             complement(16354..18006)
                     /gene="ushA"
                     /locus_tag="ACHY1N_000501"
                     /EC_number="3.1.3.5"
                     /EC_number="3.6.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HFS4042851.1"
                     /translation="MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHG
                     HFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFR
                     GMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
                     QDLKIAVIGLTTDDTAKIGNPEYFTDVEFRKPADEAKLVIQELQQTEKPDIIIAATHM
                     GHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCK
                     PDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVL
                     YTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAA
                     QMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAV
                     AQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPR
                     LDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ"
     gene            18224..19444
                     /gene="fsr"
                     /locus_tag="ACHY1N_000502"
     CDS             18224..19444
                     /gene="fsr"
                     /locus_tag="ACHY1N_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fosmidomycin MFS transporter"
                     /protein_id="HFS4042852.1"
                     /translation="MAMSEQPQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLS
                     GLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKSKATIIN
                     PLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL
                     GMLTIFLPDNRHKD"
     gene            19682..21358
                     /gene="ybaL"
                     /locus_tag="ACHY1N_000503"
     CDS             19682..21358
                     /gene="ybaL"
                     /locus_tag="ACHY1N_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaL family putative K(+) efflux transporter"
                     /protein_id="HFS4042853.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKAIAIPGAIAQIAVATLL
                     GMALSAVLGWSLMTGLVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGIAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSLAAFFLVRLFGHSQRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSR
                     TRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPD
                     IEIIARAHYDDEVTYITERGANQVVMGEREIARTMLELLETPPAGEVVTG"
     gene            complement(21491..22795)
                     /gene="gsk"
                     /locus_tag="ACHY1N_000504"
     CDS             complement(21491..22795)
                     /gene="gsk"
                     /locus_tag="ACHY1N_000504"
                     /EC_number="2.7.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HFS4042854.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLV
                     DIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKK
                     YNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALD
                     WVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            22947..23906
                     /gene="aes"
                     /locus_tag="ACHY1N_000505"
     CDS             22947..23906
                     /gene="aes"
                     /locus_tag="ACHY1N_000505"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HFS4042855.1"
                     /translation="MKPENKLPVLDLISAEMKTVVNTLQPDLPSWPATGTIAEQRQYY
                     TLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDT
                     HDRIMRLLASYSQCTVIGIDYPLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIG
                     FAGDSAGAMLALASALWLRDKQIDCGKIAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQ
                     QDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLA
                     AHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL"
     gene            complement(23903..24865)
                     /gene="hemH"
                     /locus_tag="ACHY1N_000506"
     CDS             complement(23903..24865)
                     /gene="hemH"
                     /locus_tag="ACHY1N_000506"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HFS4042856.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLL
                     WWPLLRGVILPLRSPRVAKLYASVWMEDGSPLMVYSRQQQQALAQRLPETPVALGMSY
                     GSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIR
                     DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTREL
                     ASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLET
                     LEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR"
     gene            complement(25101..25745)
                     /gene="adk"
                     /locus_tag="ACHY1N_000507"
     CDS             complement(25101..25745)
                     /gene="adk"
                     /locus_tag="ACHY1N_000507"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004017 - adenylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFS4042857.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIN
                     VDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG"
     gene            complement(25926..27800)
                     /gene="htpG"
                     /locus_tag="ACHY1N_000508"
     CDS             complement(25926..27800)
                     /gene="htpG"
                     /locus_tag="ACHY1N_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HFS4042858.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGT
                     KSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
                     EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV
                     SREILQDSTVTRNLRNALTKRVLQMLEKLAKDDADKYQTFWQQFGLVLKEGPAEDFAN
                     QEAIAKLLRFASTYTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL
                     TPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKY
                     IFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
                     "
     gene            complement(27910..28515)
                     /gene="recR"
                     /locus_tag="ACHY1N_000509"
     CDS             complement(27910..28515)
                     /gene="recR"
                     /locus_tag="ACHY1N_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFS4042859.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
                     CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF"
     gene            complement(28515..28844)
                     /gene="ybaB"
                     /locus_tag="ACHY1N_000510"
     CDS             complement(28515..28844)
                     /gene="ybaB"
                     /locus_tag="ACHY1N_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFS4042860.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            complement(28897..30828)
                     /gene="dnaX"
                     /locus_tag="ACHY1N_000511"
     CDS             complement(28897..30828)
                     /gene="dnaX"
                     /locus_tag="ACHY1N_000511"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFS4042861.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAL
                     SLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGI
                     EWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLI
                     GRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQ
                     PQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERL
                     ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPE
                     LAAKLAAEAIERDAWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNR
                     GAQQKLAEALSTLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNI
                     QTLRRFFDAELDEESIRPI"
     misc_feature    complement(29500..29564)
                     /gene="dnaX"
                     /locus_tag="ACHY1N_000511"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00382"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="DnaX frameshifting element; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00382"
     gene            complement(30957..31508)
                     /gene="apt"
                     /locus_tag="ACHY1N_000512"
     CDS             complement(30957..31508)
                     /gene="apt"
                     /locus_tag="ACHY1N_000512"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFS4042862.1"
                     /translation="MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDL
                     EYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
                     LGGEQRLEKQGITSYSLVPFPGH"
     gene            complement(31661..32038)
                     /gene="ybaN"
                     /locus_tag="ACHY1N_000513"
     CDS             complement(31661..32038)
                     /gene="ybaN"
                     /locus_tag="ACHY1N_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HFS4042863.1"
                     /translation="MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAILLILLTFAISLWFVQMPWVRIMLL
                     VILACLLFYMWRIPVIDEKQEKH"
     gene            32108..32635
                     /gene="priC"
                     /locus_tag="ACHY1N_000514"
     CDS             32108..32635
                     /gene="priC"
                     /locus_tag="ACHY1N_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
                     /protein_id="HFS4042864.1"
                     /translation="MKTALLLEKLEGQLATLRQRCAPVAQFATLSARFDRHLFQTRAT
                     TLQACLDEAGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREASAWSLREWDSAP
                     PKIARWQRKRIQHQDFERRLREMVAERRARLARVTDLVEQQTLHREVEAYEARLARCR
                     HALEKIENRLARLTR"
     gene            32649..32810
                     /gene="rsmS"
                     /locus_tag="ACHY1N_000515"
     CDS             32649..32810
                     /gene="rsmS"
                     /locus_tag="ACHY1N_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HFS4042865.1"
                     /translation="MSLENAPDDVKLAVDLIVLLEENQIPARTVLRALDIVKRDYEKK
                     LTRDDEAEK"
     gene            complement(32863..32961)
                     /locus_tag="ACHY1N_000516"
                     /pseudo
     CDS             complement(32863..32961)
                     /locus_tag="ACHY1N_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518748.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(33022..36384)
                     /gene="mscK"
                     /locus_tag="ACHY1N_000517"
     CDS             complement(33022..36384)
                     /gene="mscK"
                     /locus_tag="ACHY1N_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HFS4042866.1"
                     /translation="MTMFQYYKRSRHFVFSAFIAFVFVLLCQNTAFARASSNGDLPTK
                     ADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEETVQLRQKVAEAPEKM
                     RQATAALTALSDVDNDEETRKILSTLSLRQLETRVAQALDDLQNAQNDLASYNSQLVS
                     LQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQAQQALLNAEIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPD
                     EAARIQANPLVKQELEINQQLSQRLITATENGNQLMQQNIKVKNWLERALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDAF
                     VNKLEEGHTNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMSV
                     SKNLKSILTQQIFWVNSNRPMDWDWIKAFPQSLKDEFKSMKITVNWEKAWPAVFIAFL
                     AGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQTS
                     HWRRQIVRISLALLPIHFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRES
                     WRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLRLSGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLLM
                     FALFGVMFWAIWSDLITVFSYLDSITLWHYNGTEAGAAVVKNVTMGSLLFAIIASMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEHP
                     RVMHEPMPEVFFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIAF
                     NQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG"
     gene            complement(36512..37159)
                     /gene="acrR"
                     /locus_tag="ACHY1N_000518"
     CDS             complement(36512..37159)
                     /gene="acrR"
                     /locus_tag="ACHY1N_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HFS4042867.1"
                     /translation="MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVT
                     RGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT
                     EERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
                     RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE"
     gene            37301..38494
                     /gene="acrA"
                     /locus_tag="ACHY1N_000519"
     CDS             37301..38494
                     /gene="acrA"
                     /locus_tag="ACHY1N_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HFS4042868.1"
                     /translation="MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVT
                     VKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ
                     ATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAA
                     KAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITL
                     RAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVET
                     RPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQP
                     EQSKS"
     gene            38517..41666
                     /gene="acrB"
                     /locus_tag="ACHY1N_000520"
     CDS             38517..41666
                     /gene="acrB"
                     /locus_tag="ACHY1N_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease AcrB"
                     /protein_id="HFS4042869.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYD
                     IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG
                     KKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALG
                     VSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVG
                     YDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRL
                     RPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKNEDIEHSHTVDHH"
     gene            42212..42586
                     /gene="tomB"
                     /locus_tag="ACHY1N_000521"
     CDS             42212..42586
                     /gene="tomB"
                     /locus_tag="ACHY1N_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity modulator TomB"
                     /protein_id="HFS4042870.1"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAI
                     NLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRK
                     SGNRLFRCFVNATKENPASLSC"
     gene            42612..42830
                     /gene="hha"
                     /locus_tag="ACHY1N_000522"
     CDS             42612..42830
                     /gene="hha"
                     /locus_tag="ACHY1N_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HHA domain-containing protein"
                     /protein_id="HFS4042871.1"
                     /translation="MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     gene            43002..43552
                     /gene="maa"
                     /locus_tag="ACHY1N_000523"
                     /pseudo
     CDS             43002..43552
                     /gene="maa"
                     /locus_tag="ACHY1N_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414992.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
     gene            43668..44138
                     /gene="ylaC"
                     /locus_tag="ACHY1N_000524"
     CDS             43668..44138
                     /gene="ylaC"
                     /locus_tag="ACHY1N_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaC family protein"
                     /protein_id="HFS4042872.1"
                     /translation="MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYV
                     AFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFDVYPRYRYEDIDVLDFRVCYNGE
                     WYNTRFVPAALVEAILNSPRVADVHKEQLQKMIVRKGELSFYDIFTLARAESTS"
     gene            44302..45852
                     /gene="pdeB"
                     /locus_tag="ACHY1N_000525"
     CDS             44302..45852
                     /gene="pdeB"
                     /locus_tag="ACHY1N_000525"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308537.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeB"
                     /protein_id="HFS4042873.1"
                     /translation="MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTY
                     SSRVAIRANKVATQGKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVVYIDNNV
                     PQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
                     FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILP
                     FPEMNISIITWASTKMLQKGWHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQ
                     DAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPL
                     TLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIAL
                     ELTEREFADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETSKQEEWLRQHGVHYGQGWLYSKALPKEDF
                     LRWAEQHL"
     gene            complement(45894..46247)
                     /gene="ybaA"
                     /locus_tag="ACHY1N_000526"
     CDS             complement(45894..46247)
                     /gene="ybaA"
                     /locus_tag="ACHY1N_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1428 family protein"
                     /protein_id="HFS4042874.1"
                     /translation="MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWAS
                     DVPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRDAATQKMMSDPRMKEFGESMPFD
                     GKRMIYGGFESIIDE"
     gene            complement(46367..46463)
                     /gene="ffs"
                     /locus_tag="ACHY1N_000527"
     ncRNA           complement(46367..46463)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACHY1N_000527"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            46626..46937
                     /locus_tag="ACHY1N_000528"
     CDS             46626..46937
                     /locus_tag="ACHY1N_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HFS4042875.1"
                     /translation="MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGG
                     VLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQALLAEGVMVSGSGQIDLQRYRWN
                     Y"
     gene            complement(46968..47540)
                     /gene="ybaY"
                     /locus_tag="ACHY1N_000529"
     CDS             complement(46968..47540)
                     /gene="ybaY"
                     /locus_tag="ACHY1N_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaY family lipoprotein"
                     /protein_id="HFS4042876.1"
                     /translation="MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPA
                     IQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFV
                     LPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINKGGTKADLTLVPVQQTAVPV
                     QASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            47758..48618
                     /gene="tesB"
                     /locus_tag="ACHY1N_000530"
     CDS             47758..48618
                     /gene="tesB"
                     /locus_tag="ACHY1N_000530"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HFS4042877.1"
                     /translation="MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEV
                     RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVAST
                     VQEGVMRNHN"
     gene            complement(48666..49952)
                     /gene="amtB"
                     /locus_tag="ACHY1N_000531"
     CDS             complement(48666..49952)
                     /gene="amtB"
                     /locus_tag="ACHY1N_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HFS4042878.1"
                     /translation="MKIATIKTGLASLAMLPGLVMAAPAVADKADNAFMMICTALVLF
                     MTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINW
                     LMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
                     SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRG
                     KPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVA
                     FIGYKLADLTVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(49982..50320)
                     /gene="glnK"
                     /locus_tag="ACHY1N_000532"
     CDS             complement(49982..50320)
                     /gene="glnK"
                     /locus_tag="ACHY1N_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFS4042879.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRI
                     RTGEADEAAL"
     gene            complement(50501..52282)
                     /gene="mdlB"
                     /locus_tag="ACHY1N_000533"
     CDS             complement(50501..52282)
                     /gene="mdlB"
                     /locus_tag="ACHY1N_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HFS4042880.1"
                     /translation="MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPL
                     LISYFIDNMVAKNNLPLKMVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRT
                     DVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
                     FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSAS
                     GTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDR
                     PLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP
                     LTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQAL
                     ETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASID
                     SGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG
                     RYWQMYQLQLAGEELAASVREEESLSA"
     gene            complement(52275..54047)
                     /gene="mdlA"
                     /locus_tag="ACHY1N_000534"
     CDS             complement(52275..54047)
                     /gene="mdlA"
                     /locus_tag="ACHY1N_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HFS4042881.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD
                     GVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
                     TLFALLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVAQGSLTLGQ
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVNDGSEPVPEGRGE
                     LDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGD
                     IRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLAS
                     VHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTE
                     HQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDELAQQSDWYRD
                     MYRYQQLEAALDDAPEIREEAVDA"
     gene            complement(54077..54535)
                     /gene="decR"
                     /locus_tag="ACHY1N_000535"
     CDS             complement(54077..54535)
                     /gene="decR"
                     /locus_tag="ACHY1N_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DecR"
                     /protein_id="HFS4042882.1"
                     /translation="MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLED
                     DGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            complement(54689..55507)
                     /gene="cof"
                     /locus_tag="ACHY1N_000536"
     CDS             complement(54689..55507)
                     /gene="cof"
                     /locus_tag="ACHY1N_000536"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HFS4042883.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGR
                     HALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASM
                     HIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
                     QLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDRE
                     MLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE"
     gene            55607..57307
                     /gene="ybaE"
                     /locus_tag="ACHY1N_000537"
     CDS             55607..57307
                     /gene="ybaE"
                     /locus_tag="ACHY1N_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HFS4042884.1"
                     /translation="MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTLL
                     RQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEQALETGKQQDVLELAQLAPG
                     ELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
                     NTQRPIGDLAHHWETSTDGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQ
                     LFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTA
                     ELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQV
                     SSGISLGFCYLTLRKSPRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWT
                     IPHWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTT
                     LLAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQVMPDEE
                     NRFNALKAVFSQLMADATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
                     "
     gene            57372..58067
                     /gene="queC"
                     /locus_tag="ACHY1N_000538"
     CDS             57372..58067
                     /gene="queC"
                     /locus_tag="ACHY1N_000538"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HFS4042885.1"
                     /translation="MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEID
                     VARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
                     MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKP
                     TVMAAMKQKTGLR"
     gene            complement(58119..58517)
                     /gene="fadM"
                     /locus_tag="ACHY1N_000539"
     CDS             complement(58119..58517)
                     /gene="fadM"
                     /locus_tag="ACHY1N_000539"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase FadM"
                     /protein_id="HFS4042886.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFQWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     gene            complement(58611..58982)
                     /gene="ybaV"
                     /locus_tag="ACHY1N_000540"
     CDS             complement(58611..58982)
                     /gene="ybaV"
                     /locus_tag="ACHY1N_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFS4042887.1"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAASVAKPTTVETKAEAPAA
                     QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNLAVLTL"
     gene            complement(59133..61004)
                     /gene="ppiD"
                     /locus_tag="ACHY1N_000541"
     CDS             complement(59133..61004)
                     /gene="ppiD"
                     /locus_tag="ACHY1N_000541"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4042888.1"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNEGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDIAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKILSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            complement(61196..61486)
                     /gene="hupB"
                     /locus_tag="ACHY1N_000542"
     CDS             complement(61196..61486)
                     /gene="hupB"
                     /locus_tag="ACHY1N_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013356995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein HU-beta"
                     /protein_id="HFS4042889.1"
                     /translation="MKRKRRVNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKE
                     GDDVALVGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            complement(61677..64031)
                     /gene="lon"
                     /locus_tag="ACHY1N_000543"
     CDS             complement(61677..64031)
                     /gene="lon"
                     /locus_tag="ACHY1N_000543"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HFS4042890.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            complement(64219..65493)
                     /gene="clpX"
                     /locus_tag="ACHY1N_000544"
     CDS             complement(64219..65493)
                     /gene="clpX"
                     /locus_tag="ACHY1N_000544"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HFS4042891.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     gene            complement(65619..66242)
                     /gene="clpP"
                     /locus_tag="ACHY1N_000545"
     CDS             complement(65619..66242)
                     /gene="clpP"
                     /locus_tag="ACHY1N_000545"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFS4042892.1"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            complement(66488..67786)
                     /gene="tig"
                     /locus_tag="ACHY1N_000546"
     CDS             complement(66488..67786)
                     /gene="tig"
                     /locus_tag="ACHY1N_000546"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFS4042893.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA"
     gene            complement(68130..68447)
                     /gene="bolA"
                     /locus_tag="ACHY1N_000547"
     CDS             complement(68130..68447)
                     /gene="bolA"
                     /locus_tag="ACHY1N_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414969.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HFS4042894.1"
                     /translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
                     SIA"
     gene            68752..69330
                     /gene="yajG"
                     /locus_tag="ACHY1N_000548"
     CDS             68752..69330
                     /gene="yajG"
                     /locus_tag="ACHY1N_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414968.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFS4042895.1"
                     /translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     gene            69374..70849
                     /gene="ampG"
                     /locus_tag="ACHY1N_000549"
     CDS             69374..70849
                     /gene="ampG"
                     /locus_tag="ACHY1N_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HFS4042896.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLLPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLVCRQTLEYTRVNDNFISRTEYPAGYAFAMWTLAAGVSLLAVWLLLLTMDA
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     gene            71310..72257
                     /gene="cyoA"
                     /locus_tag="ACHY1N_000550"
     CDS             71310..72257
                     /gene="cyoA"
                     /locus_tag="ACHY1N_000550"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HFS4042897.1"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAEFDQWVAKAKQSPNTMSDMAAFEKLAAPSEYNQVEYFSNVKPDLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     gene            72279..74270
                     /gene="cyoB"
                     /locus_tag="ACHY1N_000551"
     CDS             72279..74270
                     /gene="cyoB"
                     /locus_tag="ACHY1N_000551"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HFS4042898.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     gene            74260..74874
                     /gene="cyoC"
                     /locus_tag="ACHY1N_000552"
     CDS             74260..74874
                     /gene="cyoC"
                     /locus_tag="ACHY1N_000552"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HFS4042899.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            74874..75203
                     /gene="cyoD"
                     /locus_tag="ACHY1N_000553"
     CDS             74874..75203
                     /gene="cyoD"
                     /locus_tag="ACHY1N_000553"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HFS4042900.1"
                     /translation="MSHSTDHSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQVLVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            75215..76105
                     /gene="cyoE"
                     /locus_tag="ACHY1N_000554"
     CDS             75215..76105
                     /gene="cyoE"
                     /locus_tag="ACHY1N_000554"
                     /EC_number="2.5.1.141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008495 - protoheme IX farnesyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0048034 - heme O biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heme o synthase"
                     /protein_id="HFS4042901.1"
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     gene            76290..76601
                     /locus_tag="ACHY1N_000555"
     CDS             76290..76601
                     /locus_tag="ACHY1N_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HFS4042902.1"
                     /translation="MPGKTATLPDVDKTLKNARVELKTSPDAKNKLREAAQAVGVDLS
                     AFILSAAMERAESVLDNQRRRELSNQSWELMNQLIAEPAQPTLALKALMKRKNSDGRQ
                     A"
     gene            76585..77127
                     /locus_tag="ACHY1N_000556"
     CDS             76585..77127
                     /locus_tag="ACHY1N_000556"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4042903.1"
                     /translation="MVDKHEEITLPIVLSCNYQSDITYPGQKQFDCGNPVIDKFVRAS
                     LKKSVRNSDCAAKALIDRQSGELIGICTFTAYSLEKQRVSGVLQGSQPSEIGVVRLVM
                     LGVARKYQKQGFGQDLLCDFFEHVKIIHQALPIKGVYLDADPAAINFYARLGFVQLSA
                     TPNAFGAVPMFLAIQHILAA"
     gene            complement(77183..78118)
                     /locus_tag="ACHY1N_000557"
     CDS             complement(77183..78118)
                     /locus_tag="ACHY1N_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001427098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFS4042904.1"
                     /translation="MLTKRILFSVMLIVSPSVVASEKAHELYDSIYGGKPAPDVINTL
                     HKMAESGDIDAQSLLGWEYYQPRYDTKPDVQEAIKWFELAAKQGDREAPLALGGIYYD
                     GEQVRVDYAKAYALFNQAAQHGVNLAWSRLGIMYANGQYVEVDCKKAKEYLDKGVHIY
                     GGPEDFLATCRKDMIDRKTVDDTLPVITVTRSGMRDNFLDKGFSCMDSLFATTNKLGE
                     VANLRVTFSIRRPSGKEINQTVGFAPFGLNRLNISFTDYLFGSFTSNSSLILYKPEFE
                     RKSCATVRTTIVAATATINGKDVELLKAGAIEQKW"
     gene            78526..79890
                     /gene="yajR"
                     /locus_tag="ACHY1N_000558"
     CDS             78526..79890
                     /gene="yajR"
                     /locus_tag="ACHY1N_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308508.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4042905.1"
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHMLLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPP
                     YVSSLRIEIPADIAANEALKVRLLETEGVKEVLIAEEEHSAYVKIDSKVTNRFEVEQA
                     IRQA"
     gene            complement(80018..80509)
                     /gene="yajQ"
                     /locus_tag="ACHY1N_000559"
     CDS             complement(80018..80509)
                     /gene="yajQ"
                     /locus_tag="ACHY1N_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide binding protein YajQ"
                     /protein_id="HFS4042906.1"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     gene            80677..81588
                     /gene="panE"
                     /locus_tag="ACHY1N_000560"
     CDS             80677..81588
                     /gene="panE"
                     /locus_tag="ACHY1N_000560"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFS4042907.1"
                     /translation="MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVET
                     DGSIFNESLTANDPDFLATSDLLLVTLKAWQVYDAVKSLASTLPVTTPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     gene            81551..82141
                     /gene="yajL"
                     /locus_tag="ACHY1N_000561"
     CDS             81551..82141
                     /gene="yajL"
                     /locus_tag="ACHY1N_000561"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HFS4042908.1"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
                     ITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(82195..83643)
                     /gene="thiI"
                     /locus_tag="ACHY1N_000562"
     CDS             complement(82195..83643)
                     /gene="thiI"
                     /locus_tag="ACHY1N_000562"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFS4042909.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
                     QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNR
                     TWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
     gene            83849..84091
                     /gene="xseB"
                     /locus_tag="ACHY1N_000563"
     CDS             83849..84091
                     /gene="xseB"
                     /locus_tag="ACHY1N_000563"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFS4042910.1"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            84091..84990
                     /gene="ispA"
                     /locus_tag="ACHY1N_000564"
     CDS             84091..84990
                     /gene="ispA"
                     /locus_tag="ACHY1N_000564"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HFS4042911.1"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDANMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
                     LAEQSLDTSALEALADYIIQRNK"
     gene            85015..86877
                     /gene="dxs"
                     /locus_tag="ACHY1N_000565"
     CDS             85015..86877
                     /gene="dxs"
                     /locus_tag="ACHY1N_000565"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFS4042912.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
     gene            87057..88031
                     /gene="yajO"
                     /locus_tag="ACHY1N_000566"
     CDS             87057..88031
                     /gene="yajO"
                     /locus_tag="ACHY1N_000566"
                     /EC_number="1.17.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="HFS4042913.1"
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALKLQKQHGWAQFISMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGR
                     LTRPWGETTARLVSDEVGRNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHAVVGFK"
     gene            complement(88085..88603)
                     /gene="pgpA"
                     /locus_tag="ACHY1N_000567"
     CDS             complement(88085..88603)
                     /gene="pgpA"
                     /locus_tag="ACHY1N_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFS4042914.1"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGILS"
     gene            complement(88581..89558)
                     /gene="thiL"
                     /locus_tag="ACHY1N_000568"
     CDS             complement(88581..89558)
                     /gene="thiL"
                     /locus_tag="ACHY1N_000568"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009030 - thiamine-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HFS4042915.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLHDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTFDWKGYDHFATP"
     gene            complement(89636..90055)
                     /gene="nusB"
                     /locus_tag="ACHY1N_000569"
     CDS             complement(89636..90055)
                     /gene="nusB"
                     /locus_tag="ACHY1N_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFS4042916.1"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            complement(90075..90545)
                     /gene="ribE"
                     /locus_tag="ACHY1N_000570"
     CDS             complement(90075..90545)
                     /gene="ribE"
                     /locus_tag="ACHY1N_000570"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HFS4042917.1"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            complement(90634..91737)
                     /gene="ribD"
                     /locus_tag="ACHY1N_000571"
     CDS             complement(90634..91737)
                     /gene="ribD"
                     /locus_tag="ACHY1N_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HFS4042918.1"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSTQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDEQTQVL
                     YPQQNLRQPVRIVIDSQNRVTPEHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQVGLVDELIVYIAPKLLGSDARGLC
                     SLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            complement(91741..92190)
                     /gene="nrdR"
                     /locus_tag="ACHY1N_000572"
     CDS             complement(91741..92190)
                     /gene="nrdR"
                     /locus_tag="ACHY1N_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFS4042919.1"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     gene            92341..92880
                     /gene="yajI"
                     /locus_tag="ACHY1N_000573"
     CDS             92341..92880
                     /gene="yajI"
                     /locus_tag="ACHY1N_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HFS4042920.1"
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSALNQEMTQLN
                     QETVKITQQNRLNAKSSSGVYLLPGAKTPARLKSQIGTLRMSLVNITPDTDGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     ISVDQLGFVRIHDIQPVMQ"
     gene            93179..94063
                     /gene="tsx"
                     /locus_tag="ACHY1N_000574"
     CDS             93179..94063
                     /gene="tsx"
                     /locus_tag="ACHY1N_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HFS4042921.1"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGNAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     gene            complement(94240..94587)
                     /gene="yajD"
                     /locus_tag="ACHY1N_000575"
     CDS             complement(94240..94587)
                     /gene="yajD"
                     /locus_tag="ACHY1N_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease YajD"
                     /protein_id="HFS4042922.1"
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     gene            complement(94716..95687)
                     /gene="secF"
                     /locus_tag="ACHY1N_000576"
     CDS             complement(94716..95687)
                     /gene="secF"
                     /locus_tag="ACHY1N_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HFS4042923.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            complement(95698..97545)
                     /gene="secD"
                     /locus_tag="ACHY1N_000577"
     CDS             complement(95698..97545)
                     /gene="secD"
                     /locus_tag="ACHY1N_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HFS4042924.1"
                     /translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
                     ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
                     LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     gene            complement(97573..97905)
                     /gene="yajC"
                     /locus_tag="ACHY1N_000578"
     CDS             complement(97573..97905)
                     /gene="yajC"
                     /locus_tag="ACHY1N_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFS4042925.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            complement(97928..99055)
                     /gene="tgt"
                     /locus_tag="ACHY1N_000579"
     CDS             complement(97928..99055)
                     /gene="tgt"
                     /locus_tag="ACHY1N_000579"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFS4042926.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
     gene            complement(99111..100181)
                     /gene="queA"
                     /locus_tag="ACHY1N_000580"
     CDS             complement(99111..100181)
                     /gene="queA"
                     /locus_tag="ACHY1N_000580"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051075 - S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFS4042927.1"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDDRSVLDILNSIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     gene            100274..100855
                     /gene="acpH"
                     /locus_tag="ACHY1N_000581"
     CDS             100274..100855
                     /gene="acpH"
                     /locus_tag="ACHY1N_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008770 - [acyl-carrier-protein]
                     phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HFS4042928.1"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFV
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
                     DSWYDLDAHYDALETRFWQFYPRMMAQASHKAL"
     gene            complement(100860..102677)
                     /gene="malZ"
                     /locus_tag="ACHY1N_000582"
     CDS             complement(100860..102677)
                     /gene="malZ"
                     /locus_tag="ACHY1N_000582"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308480.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004558 - alpha-1,4-glucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HFS4042929.1"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EEMSVSMHKQRSQQQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
                     HVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWSMDGW
                     RLDVVHMLGEAGGARNNMQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     TALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
                     VLPASPFLNVAQWQRKEGHGQLTNGILALPAISATVWMN"
     gene            complement(102833..104206)
                     /gene="proY"
                     /locus_tag="ACHY1N_000583"
     CDS             complement(102833..104206)
                     /gene="proY"
                     /locus_tag="ACHY1N_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HFS4042930.1"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     gene            complement(104282..105601)
                     /gene="brnQ"
                     /locus_tag="ACHY1N_000584"
     CDS             complement(104282..105601)
                     /gene="brnQ"
                     /locus_tag="ACHY1N_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HFS4042931.1"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     gene            complement(106008..107303)
                     /gene="phoR"
                     /locus_tag="ACHY1N_000585"
     CDS             complement(106008..107303)
                     /gene="phoR"
                     /locus_tag="ACHY1N_000585"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HFS4042932.1"
                     /translation="MLERLSWKRLVLELLLCCFPAFILGAFFGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
                     EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD"
     gene            complement(107361..108050)
                     /gene="phoB"
                     /locus_tag="ACHY1N_000586"
     CDS             complement(107361..108050)
                     /gene="phoB"
                     /locus_tag="ACHY1N_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HFS4042933.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     gene            108240..109442
                     /gene="sbcD"
                     /locus_tag="ACHY1N_000587"
     CDS             108240..109442
                     /gene="sbcD"
                     /locus_tag="ACHY1N_000587"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HFS4042934.1"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITADEYLHDIQRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLH
                     TLAGEHEA"
     gene            109439..112582
                     /gene="sbcC"
                     /locus_tag="ACHY1N_000588"
     CDS             109439..112582
                     /gene="sbcC"
                     /locus_tag="ACHY1N_000588"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
                     /protein_id="HFS4042935.1"
                     /translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQV
                     QSLTASLQVLTDEEKQLLTAQQQEQQSLNWLTRLDELQQEASRRQQALQQALAEEEKA
                     QPQLAALSLAQPARNLRPHWERIAEHSAALAHTRQQIEEVNTRLQSTMALRASIRHHA
                     AKQSAELQQQQQSLNTWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQ
                     NVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGAALRGQLDALTKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDEHERQLRLLSQRHELQGQ
                     IAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQQRQN
                     ELTALQNRIQQLTPILETLPQSDDLPHSEETVALDNWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAETLAQHQQHRPDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDA
                     DNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQL
                     TRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
                     KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVK
                     KINGLGYSKLESTFAVK"
     gene            112708..113892
                     /gene="araJ"
                     /locus_tag="ACHY1N_000589"
     CDS             112708..113892
                     /gene="araJ"
                     /locus_tag="ACHY1N_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414930.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
                     /protein_id="HFS4042936.1"
                     /translation="MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMI
                     SYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSG
                     FPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTF
                     LLIAVFNIAVMASVYFWVPDIRDEAKGKLREQFHFLRSPAPWLIFAATMFGNAGVFAW
                     FSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNVLSGRISGRYSPLRIAAVTDFIIV
                     LALLMLFFCGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFN
                     LGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADSPVLAKP
                     LG"
     gene            complement(114035..114943)
                     /gene="mak"
                     /locus_tag="ACHY1N_000590"
     CDS             complement(114035..114943)
                     /gene="mak"
                     /locus_tag="ACHY1N_000590"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414928.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HFS4042937.1"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFATDYRRLSGHALKGSEIIRLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVGQLIKQFVFGGE
                     CETPVRKAKHGDSSGVRGAAWLWPQE"
     gene            115068..115979
                     /gene="rdgC"
                     /locus_tag="ACHY1N_000591"
     CDS             115068..115979
                     /gene="rdgC"
                     /locus_tag="ACHY1N_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HFS4042938.1"
                     /translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
                     WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLSMENPIELTLTEWVRSGSAAQGFQLIDEAELKSLLEDGGVIRAKKQDLTSEE
                     ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQNLIEGLGGEAQR"
     gene            complement(116057..116140)
                     /locus_tag="ACHY1N_000592"
     CDS             complement(116057..116140)
                     /locus_tag="ACHY1N_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4042939.1"
                     /translation="MTQRPWSKLQHKTHNIAALKIIARRSE"
     gene            complement(116137..116478)
                     /locus_tag="ACHY1N_000593"
                     /pseudo
     CDS             complement(116137..116478)
                     /locus_tag="ACHY1N_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308469.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing protein"
     gene            complement(116626..116910)
                     /gene="ppnP"
                     /locus_tag="ACHY1N_000594"
     CDS             complement(116626..116910)
                     /gene="ppnP"
                     /locus_tag="ACHY1N_000594"
                     /EC_number="2.4.2.1"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HFS4042940.1"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            complement(116982..117659)
                     /gene="aroM"
                     /locus_tag="ACHY1N_000595"
     CDS             complement(116982..117659)
                     /gene="aroM"
                     /locus_tag="ACHY1N_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HFS4042941.1"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
                     VMAEYAPEAGEDTILTLLNDIQLAHVSRRKVERDLQGVVEVLDNQGYDVILLMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEEMLPVQAQKWQILQKSPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFHQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLV"
     gene            complement(117917..118108)
                     /gene="yaiA"
                     /locus_tag="ACHY1N_000596"
     CDS             complement(117917..118108)
                     /gene="yaiA"
                     /locus_tag="ACHY1N_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HFS4042942.1"
                     /translation="MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     gene            complement(118158..118682)
                     /gene="aroL"
                     /locus_tag="ACHY1N_000597"
     CDS             complement(118158..118682)
                     /gene="aroL"
                     /locus_tag="ACHY1N_000597"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HFS4042943.1"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMT
                     VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
     gene            complement(118865..119323)
                     /gene="yaiI"
                     /locus_tag="ACHY1N_000598"
     CDS             complement(118865..119323)
                     /gene="yaiI"
                     /locus_tag="ACHY1N_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFS4042944.1"
                     /translation="MTIWVDADACPSVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
     gene            119443..120252
                     /gene="proC"
                     /locus_tag="ACHY1N_000599"
     CDS             119443..120252
                     /gene="proC"
                     /locus_tag="ACHY1N_000599"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFS4042945.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAA
                     LHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     gene            complement(120269..121384)
                     /gene="adrA"
                     /locus_tag="ACHY1N_000600"
                     /gene_synonym="dgcC"
     CDS             complement(120269..121384)
                     /gene="adrA"
                     /locus_tag="ACHY1N_000600"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HFS4042946.1"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVVYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVREGLNTLRLPNTPQVTLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     gene            complement(121486..121806)
                     /gene="psiF"
                     /locus_tag="ACHY1N_000601"
     CDS             complement(121486..121806)
                     /gene="psiF"
                     /locus_tag="ACHY1N_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414918.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HFS4042947.1"
                     /translation="MKITLLVTLLFGLVFLTTVGAAEKTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     gene            complement(121925..123340)
                     /gene="phoA"
                     /locus_tag="ACHY1N_000602"
     CDS             complement(121925..123340)
                     /gene="phoA"
                     /locus_tag="ACHY1N_000602"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HFS4042948.1"
                     /translation="MKQSTIALALLTLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTGDHTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
                     NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVNDAASLNSVTEANQQKP
                     LLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADH
                     AHASQVVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     gene            complement(123441..123701)
                     /gene="iraP"
                     /locus_tag="ACHY1N_000603"
     CDS             complement(123441..123701)
                     /gene="iraP"
                     /locus_tag="ACHY1N_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HFS4042949.1"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ"
BASE COUNT        29639 a        32991 c        31261 g        29946 t
ORIGIN      
        1 ttatgatttt attagtctga gttatttttg tagggctata tttaaaatta ttaaacccca
       61 ccgattcaga ttaatatcgc aatagaaaga taggaaatca ccaattcaat aacatcatca
      121 atgaaacata ttgtagaatt aatttaaact aggcgttcca ttcaaccaga acgcccctta
      181 tttactctct tcaccccgca aactgcctga acagcgcctt acccttaacc agtcgcgcac
      241 ccagccagcc gccgaaaagc gacagcagca gcgcaccgct gcacggcaga acaatccaca
      301 atcgccagtc tggctcccac ggaaaatcaa acactttcgc ctgcaacact gccagcgccg
      361 tttccgcacc aattgcggct accaggccag aaacaaaccc aagcatggcg aactcacacc
      421 acaatgtcgt gcgcagcagc tttttccccg caccgagtgt gcgccacacc accagctcca
      481 gatgacgctg acgcattccc acctgcacct gagccagcaa cagcaacata ccgcaggcgg
      541 tgaccagtac caccatcact tccagcgccc gacttacctg ctccagcacc tgaccgacct
      601 gttttaaaat cgcgccaata tctaacagac taatggtcgg gaactggcgg ttgagttgtg
      661 tcaacatgcc gttgccattc tcccagcgga aactggtaag ccagctctgc ggttgcccgt
      721 ctaatgcccc ttcagggaaa ataaaataga aattaggccg cagactttcc cagtccactt
      781 tgcgcaggct ggtcacttta gcgcggaact cctgggtatc gcccataaaa gtcacggtat
      841 caccgagggc aacgtttaag cgtttcgcca gcccctcttc catcgacact tcatcggctt
      901 ttggcggcca gttaccggcg acaatcggat tatgatcggg ccgcgtattt tgccaggtaa
      961 gattgagttc gcggttaagc gcctcatctt cattaccttc tgtcggctta tcgttaatcg
     1021 ccgtcagccg cgcccgcacc accggataaa acgattccgg gactatctga tgttccgcga
     1081 ggaacgcttt tagcggtgct acctgttctg tggcgatgtt aattaaaaag tagttcgggc
     1141 tttctggagg tagctgctgc tgccagcggt cgagcagatc accacgcaac accagcagca
     1201 gtgccaacag cataaaggag agcgaaaatg ccgaaagctg gcttaacgtt gaccacggct
     1261 gacgtaacag gcggctaacc gccaggcgca gaggcagcga tttcagcgtc atgcggcgaa
     1321 gtacattcag cagcatccag cctagaacac cgcacagcaa agccagtact accgcgcccg
     1381 ccagcaccgc ccagagcagc atactgccgc ccattaatcc ggcgagcagc agcacaacca
     1441 ccacactgac aatcggcaga taaaacttca gcggccagac gttcgctacc acatcattac
     1501 gtaatacgcg taaaggctgc gttgccagca acaagcggta cggtcgtagc cccaccagca
     1561 gcgagatgac tgtcatggtg ccgagcgccc acagccacgg ccagaggctg gctggcggta
     1621 gtgcagcagg cagaacgggc ttgagcagca ccatcaacac gttttcgaac aacaggccta
     1681 tcgccccacc ggtaacggcc gaaagcaaca gcaccatcaa ccactgaccg acgattagct
     1741 tacgcagttg cgctcgccct gcccccagcg ttttgaggat cgccaccaga tcgtagcgac
     1801 tgcgacagta atgattcatc gctaccgcca ctgctgccac tgccagcagc aaggtcagaa
     1861 gcgccgaaag cagcaggaac tgttgcgagc gttccatcga tcgccccagc gcgccttcgt
     1921 cctgttccag accgtaccag cgttgttcgg gtttaagctg aggtaacaac catttctcat
     1981 agccgtcgag ctggttctca ctgccgccga atttatagcg ccaggtgacc cgactccccg
     2041 gctgcacggc tccggtttta tcgacatccg ccagattcat catcagacgc ggagccatct
     2101 ggaaggggtt aaaaccggaa tccggttcct gaatcacttc tccggcaatc cgcaaggtgg
     2161 catcgcccac gtcaatggtg tcgcccgttt tcaggttaag cagcgccatc aggcgtgggg
     2221 ccagcaatac gctgcccgcc tgcggtttca ggccaggggg attagtttgc agatcgccat
     2281 acatcgggta gatatcatcc accgctttga cgttcgccag ctgcggtgtg tcgcctgcaa
     2341 atgtcatggt ggcgaaagtc agctgcttgc cgactttcag gccgcgcttt tgcgcttcct
     2401 ccagccatgc ttgcggcact tcgcgcgaac tgcgcaacgc ccgatcgccc gccataaact
     2461 cccggctttg ttggcttaag cccttctcca tgcgatcgct gatattgccc agcgccagca
     2521 cgcaggccac cgccaggctt agcgccagcc agacaattaa tagcgacggc gaacgccatt
     2581 cgcgccagaa ccaacgtgca atcatgcttc ctcctgcaac tgcccgttca ccagccgtaa
     2641 gcagcggtcg cagcgtgccg ccagttgcag gtcgtgggtc accataatca acgtggtgcc
     2701 atgttcacgg ttgagggaaa acagcaggtc ggcaatttta tcgcccgtct ggcggtcaag
     2761 gttgccggtg ggttcgtcgg caaacagcac atcaggtcga ccattaaagg ctcgtgccag
     2821 cgccactcgt tgctgttcac cgccggaaag ctgtgccgga agatgaccca gacgtttacc
     2881 cagccctaac tgttcgagca acgctttcgc cccgttacga ctttccgcgc tactctcacc
     2941 gcgcagcaga gccggaagct cgacgttttc cagcgcgtta agggtaggaa ttaacataaa
     3001 tgactgaaaa acaaagccga cgtgcttcgc gcgcaacttt gcccgcgctt cttcgtccat
     3061 attatgtagc ggttgtccca ccagactcac ttcgccactg ctgccgtcat caagcccggc
     3121 gaggatcgcc agcaaggttg acttacccga tcccgactcg cccaccagtg cgatggtctc
     3181 gccacgtttg acaaccagct caactccggt gaggatggag agttcatgct ccccctgacc
     3241 gacggacttc ttaagatgat gaacttcaac aatgttttcc gctggcattt gcccttcctg
     3301 ttcctggtcc tgttaacctt ccgtgccgcc gcagcggaca cgttattgat tctgggtgat
     3361 agcctgagcg ccgggtatcg aatgtctgcc agcgcggcct ggcctgcctt gttgaatgat
     3421 aagtggcaga gtaaaacgtc ggtagttaat gccagcatca gcggcgacac ctcgcaacaa
     3481 ggactggcgc gccttccggc tctgctgaaa cagcatcagc cgcgttgggt gctggttgaa
     3541 ctgggcggca atgacggttt gcgtggtttt cagccacagc aaaccgagca aacgctgcgc
     3601 cagattttgc aggatgtcaa agccgccaac gctgaaccat tgttaatgca aatacgtctg
     3661 cctgcaaact atggtcgccg ttataatgaa gcctttagcg ccatttaccc caaactcgcc
     3721 aaagagtttg atgttccgct gctgcccttt tttatggaag aggtctacct caagccacaa
     3781 tggatgcagg atgacggtat tcatcccaac cgcgacgccc agccgtttat tgccgactgg
     3841 atggcgaagc agttgcagcc tttagtaaat catgactcat aaagcaacgg agatcctgac
     3901 aggtaaagtt atgcaaaaat cggtcttaat taccggatgt tccagtggaa ttggcctgga
     3961 aagcgcgctc gaattaaaac gccagggttt tcatgtgctg gcaggttgcc gaaaaccgga
     4021 tgatgttgag cgtatgaaca acatgggatt taccggcgtg ttgatcgatc tggattcacc
     4081 agaaagtgtt gatcgcgcag cagacgaggt aatcgccctg accgataatt gtctgtatgg
     4141 gatctttaac aatgccggat tcggcatgta tggccccctt tccaccatca gccgtgcgca
     4201 gatggaacag cagttttccg ccaacttttt cggcgcacac cagctcacca tgcgcctgtt
     4261 acccgcgatg ttaccgcacg gtgaagggcg tattgtgatg acatcatcgg tgatgggatt
     4321 aatctccacg ccgggtcgtg gcgcttacgc ggccagtaaa tatgcgctgg aggcgtggtc
     4381 agacgcactg cgcatggagc tgcgccacag cggaattaaa gtcagcctga tcgaacccgg
     4441 tcccattcgt actcgcttca ccgacaacgt caaccagacg caaagtgata aaccagtcga
     4501 aaatcccggc atcgccgccc gctttacgtt gggaccggaa gcggtggtgg acaaagtacg
     4561 ccatgctttt attagcgaga agccgaagat gcgctatccg gtaacgctgg tgacctgggc
     4621 agtaatggtg ctcaagcgcc tgctgccggg gcgcgtgatg gacaaaatat tgcaggggtg
     4681 agttgaagcg cgcgcttaag cccccatgtc aaagaaaata tcgacaacag agagcgactc
     4741 catgtccgta gaaaatattg tcaacattaa cgaatctaac ctgcaacagg ttcttgaaca
     4801 gtcgatgacc actccggtgc tgttctattt ttggtctgaa cgtagccagc actgtttgca
     4861 gttaaccccg atcctggaaa gcctcgcggc gcagtacaac gggcaattta ttctggcgaa
     4921 gctggactgt gacgcggagc agatgattgc cgcccagttt ggtctgcgcg cgattccgac
     4981 cgtgtatctg ttccagaacg ggcaaccggt agatggcttc caggggccgc aaccggaaga
     5041 ggcgatccgc gccctgctgg ataaagtgct gccgcgcgaa gaagagctga aagcgcagca
     5101 ggcgatgcaa ctgatgcagg aaggcaatta caccgatgcc ctgccattgc tgaaagacgc
     5161 ctggcagttg tcgaatcaga acggggagat cggcctgctg ctggcagaaa cgctgattgc
     5221 gctgaaccgt tctgaagatg cggaagcggt gctgaaaacc attccgttgc aggatcagga
     5281 cacccgctac caggggctgg tggcgcaaat cgaactgctg aagcaggcgg ctgatacgcc
     5341 ggaaattcaa cagttgcaac agcaggtggc ggagaatcca gaagatgccg cactggcgac
     5401 gcaactggct ctgcaactgc accaggttgg gcgcaatgaa gaggcgctgg agttgctgtt
     5461 cgggcatctg cgtaaagatc tcaccgccgc agacggtcag acacgtaaaa cgttccagga
     5521 gatcctcgct gcgctgggta cgggtgatgc actggcgtcg aagtatcgcc gccagctgta
     5581 tgcattgttg tattgatatt ccgttgatcg gcacatgaac cacaacgccg gatgcgatgc
     5641 tgcgcatccg gcatcgcatc atttcttctt caattgcgtc accaccaact ggtggcgcga
     5701 attataaaac ttacgatagg ttaaatagca ggcaataatg gtcgacaagc tggcggttga
     5761 gagcagcata aaggtcacca taatctgata tttaatcgcc ttcaccggat caatcccggc
     5821 aaatatcagc ccggacatca ttcctggtaa actcactaag ccaaccgttt ttgctgaatc
     5881 gaccgtcgga attaaagccg cgcgaatact gtcgcgaatc aatatcgctg aagcctgctt
     5941 cggcgtcgca ccaagactca gtttctcctg aatctgttgc tgttcgctaa tgacccgttg
     6001 ccctaaattg ttgtaacaca accccaccgc taccatggcg ttaccggcaa tcatcccggc
     6061 gatagggatc acctgcatcg ggataaattc aatcgaccca gagagaatca gcaccgccag
     6121 ggtaattccc gccccgaccg taatggcaat aaacgatgag ataaaagctt tagcaatata
     6181 tttactgcgt ttttgcgcgt tccacgccgc attaaagcag ataaataaca ccatcaataa
     6241 tgtcaggctg gcatcatcca cgctgaaaat atacttcagc acatagccga caataatcag
     6301 ctgaattatc gctcgcccga cgctccagaa aatatctttc tccagcgcca gtttttcttt
     6361 atggctaatt aagattgcca ccaccaccag cattaatgcc agtgccaatg attcgttagt
     6421 aatattatgc gagttcatag cgtgcttcct gcatttctcc ggcatgcggt tgcagtgtaa
     6481 tcactttatc cgcatgatta atttcgtctt tatcgtgtgt cacccacagc acggcaatat
     6541 tttgctcgcg cacataacga tggatcatct cattaacgtt atgtttatta ctttcatcca
     6601 gcgcactggt gatttcatcc agcaataaaa ccttcggcat aaattgcagg ttacgaatca
     6661 gtgagatgcg ttgtttttca ccaccagata gctcggcgat atttttcgtc aaaatgctgt
     6721 ccggcaaagc gaagcgttcg agaaaatcga gaaaaatggc cgggtcaggc tgctggttac
     6781 ggatctgcca gggaaagatc agattatcgt ataccgtatc gccaaacagc gtcggcgtct
     6841 gggcgcagta agagacttgc tggcggtaga tttctggctt tagtgtgctg acatcctcac
     6901 cttcaaacag taacgttccg ctggttgggc tgatcaatga agcaactatt tttagcagcg
     6961 tacttttgcc acaaccggaa ggaccggtaa ttaacttaaa ttcgccagca cgcagcgaaa
     7021 aattgatgtt attaagaatc ttcgcatcac ccgccagata tcctacgttt tgtagctgaa
     7081 gcaaaggact attttcctgc atcactgttc cctttttctg atttttacta aaaacagttt
     7141 atccttcgca ggaataaggg ggaactctct ttcagtaatc aggtataatt tgtttaatca
     7201 agcagcaatt ttgctgatta tggacggtac aacaggaggt ttttccgatg cttatcttta
     7261 tcccgattct catttttgtc gcgctggtca ttgtcggcgc gggcgtcaaa atcgtgccgc
     7321 agggctatca atggacggta gaacgttttg gtcgctatac caaaacgtta cagccggggc
     7381 tcagtctggt ggtgccgttt atggatcgca ttggtcgcaa gatcaatatg atggagcaag
     7441 tgctcgatat cccttcccag gaagttatct cgaaagataa cgccaacgtt accatcgacg
     7501 cagtctgttt tattcaggtg attgacgcgc cgcgcgcggc ttatgaagtc agcaatctgg
     7561 agctggcgat catcaacctg accatgacta acatccgtac cgtgttgggt tcaatggaac
     7621 ttgacgaaat gctctctcag cgcgacagca tcaactcacg cctgctgcgt attgtcgatg
     7681 aagccaccaa cccgtggggg attaaagtca cccgtattga aattcgcgac gtgcgcccac
     7741 cggcagagct tatctcttca atgaacgcgc agatgaaagc ggaacgtacc aaacgcgctt
     7801 acattcttga agcggaaggg atccgtcagg cggaaatcct caaagccgaa ggtgaaaaac
     7861 agtcgcaaat cctgaaagcg gaaggcgaac gtcagtcggc gtttttacag gctgaagcgc
     7921 gtgaacgttc cgccgaagca gaagcccgcg ccaccaaaat ggtgtctgaa gctatcgcct
     7981 ccggtgatat tcaggcggtg aactacttcg tagcgcagaa atacaccgaa gcgttacagc
     8041 agatcggttc ctccagtaac agcaaagtag tgatgatgcc attagaggcc agcagcctga
     8101 tggggtcgat tgccgggatt gccgagctgg tgaaagacag cgccaacaaa cggactcagc
     8161 catgatggag ttaatggtcg ttcatccaca tattttctgg ctcagtctcg gcggtttgct
     8221 gctggcagcc gagatgctgg gcggaaatgg ttatttgttg tggagcggcg tggcagcggt
     8281 gattaccggc ctggtggtct ggctggtgcc gctgggttgg gagtggcaag gggtaatgtt
     8341 tgccatcctg acgctgctcg ccgcctggct gtggtggaaa tggttgtcgc ggcgggtgcg
     8401 cgaacaaaag cacagcgata gtcatttaaa ccagcgcggg cagcagctga ttggccgacg
     8461 ttttgtgctg gaatctccgc tggtcaacgg gcgcggtcat atgcgcgtcg gtgacagttc
     8521 atggcctgtc agcgccagcg aggatctcgg tgcaggtacg catgttgaag tcattgcgat
     8581 agaagggata accctacata tccgagccgt ctcgtcttaa tcaccctgcc cgatgatgac
     8641 agcagccgga gagattttcg ataatcgggc agtcggcgct gtcatcgcca gggcaggcat
     8701 tcgccagtgc cagcagctgg tcgcgcatgg attgcagctc ctcaatgtgt cgttcgatct
     8761 ccgccacctt ctccagcgtg cgccgtttga cgtcggcgct gtgccgctgc gggtcgttaa
     8821 acagattcac cagctcgccg ctctcttcca ggttaaagcc cacctgccgt gcctggcgca
     8881 gtaaggtcag ttcgttgaga tgctgctgcg tgtaggtgcg ataaccgttt tcgctgcgca
     8941 tcggcggcgt caccagcccc ttctcttcat agaagcgaat ggctttgctg gtcaggccgg
     9001 taatttttgc tacatcgctg atgttcatcg ttcgcgcaac gcctcctgtg ctttgttaaa
     9061 gggtttcaac agatattcaa gcacgttttt ttgccagtgc gaatatcgac cgccaccaca
     9121 ataatacagg aagtactgcg cacagagaga tgttatacgg ttttattgcg cttcatgacc
     9181 attgccacaa taaggctgag taagagtgag ccaataatcc atatcaacgc acggctaccc
     9241 tgggaccaca gactgtagat aaagccaacg atcaccaaca acatcaccaa cgtaccaacg
     9301 ataagaatcg gcaacgaggc gtgaatatca tgacgcaggc ggatcgccac cacaaacacc
     9361 gccaggtagc aaatcaaaaa ggtggcgctg gcaacactgg cgagtgagcc taaatttagc
     9421 gccgccgtca tcagcataat caacaccacg acaatgatgt tgccccaggt actctgccgc
     9481 cacagggatt tattcattag cttcggcagt tcgcgttcgc tgcccatgtt gtccatgatg
     9541 ttaaacacgg cgaacaggtt cgcgttaatg gctgaagccg tcgccagtaa agcgccgatg
     9601 acgacgatca cataacccac atgtccgagc agcggagaag cagcctgcgc aacggcggta
     9661 tcggcatatt tttctaactc taatgccgat acatcgctaa gcaaaaccag tgccagcgag
     9721 atataaagca acgtggtaac gccaatcgcc accagaaacg cccgcggcat aatgacctgc
     9781 ggatctttca ctttatccgc cgcgttcgcc atcatgccaa agcccgcata ggcaaggaag
     9841 gttatcccga tacaggagaa gaacgcaccg gagctggggg gcgcagagac ggaaatatgc
     9901 gccggttgca gcgaccagac accggcaata atcagcaata acaggatcat cattttaatg
     9961 ccgacgagga tcacttccag ccgccctacc gcatggttgc ttaaggagtt gaaaagcgtc
    10021 atcaccgcaa tgatccccaa cgcgtagagc aaaataaggt gctcctcctg gctgccttca
    10081 tgcaaaaact gcacggcata agcgccaaaa gcacgggcga ccatggcgat gctcaccgcc
    10141 agcgtcaaca ggtacagtaa cgagagcgcc agcgaaaaga cgccgttgcc taatccgcga
    10201 cgaaagaagt cgataatgcc gccattgctg ggatagctcg cccccagacg cgcataggca
    10261 taaccggaaa acatcgccac aataccgcca aaagcaaagg cgacccaggt cgaggcttcc
    10321 attagcaacg cagcctgccc cagcagcgcg aagatccccg cccccaccat tgccccaata
    10381 ccgatggaaa cgacattcca tagaccgagg ggtttgttac cgttattacc ttccgtgttc
    10441 atcatgatca gcccttaaac acgttatagc cgagttgatt agcgaccgat gccaccattt
    10501 tttgaccgcg aacactgttg ccttcttcgt ccagcggtgg tgagaacgcg gcaattccca
    10561 tcacgccagg gacgaccgcc agaataccgc cacctacacc gcttttgccc ggtaaaccaa
    10621 cgcgatacgc ccagtcaccg gagcgaccat acagcccttc catcatcatt tcggccagaa
    10681 tgtacggcac gttgtcggcc tgaagaacgc gttcatgcgt cagcggattc acaccccccg
    10741 ccgccagcgt cgcgccaagt gttgccagtt caacagtatt gaggagcgtg gagcactgac
    10801 gggtgtacac gtcacaggct tccattgcat cacaatagag atatccggcg gagtacagca
    10861 gccaggcaat ggcccggtta tggaagttgg ttgtttgttc cgactggttg acttcgtcag
    10921 agagcgctac ctgctcacca gccagttgct gttggatatg taaaattcgc tgccagcgtt
    10981 gttcaacatt ttcagcgtta atcaggctgg tggtggcaat ggcgccagca tttaccagtg
    11041 gcgacagtgg tttgccgcca tgcaactcta aggcgataac tgagttaaag ggcaatccgg
    11101 tcgggtcagc gccaattttg tcctgtaccg cctgcgggcc gacatcttct aacgcaaggg
    11161 ctaacgtaca gactttcgag atggattcca gcgcaaagcg gtaatcacta tcacccgcgc
    11221 gatagatgtt gccatcgcag gtcacaatag ccactgctgc cagttgacta ggtacattcg
    11281 ccagaaaggg aatgtagtcg gcattttgtc cgccgttaag tgagtgaaat tgggtgtaag
    11341 cctgatccac tgcctgctgt aatttgtttg catctaacat cttttgttaa ctccttttta
    11401 tagatgcggg aggtaattcc tcaccccggt gccgattttc aggcatcttg atttaactta
    11461 gcacccgcaa cttaactaca ggaaaacaaa gagataaatg tctaatcctg atgcaaattg
    11521 agccaatttt ttaatcttta cggactttta ctcgcctggt ttattaattt cttgaccttc
    11581 cccttgctgg aaggtttaac ctttatcaca gccagtcaaa actgtcttaa aggagtgttt
    11641 tatgtcacaa actatcgacc tgaccctgga cggcctgtcc tgcggtcact gcgttaaacg
    11701 cgtgaaagaa agtctcgaac agcgcccgga tgtggaacaa gcggatgtgt ctatcactga
    11761 agcgcacgtt accgggactg ccagtgcaga acagctgatc gaaaccatca aacaagcggg
    11821 ttatgacgca tctgtaagcc acccaaaggc taaaccgctg gcggagtcat caatcccgtc
    11881 ggaagcactg acagcggttt ctgaggcgct tccggcagcg accgccgatg acgatgacag
    11941 ccagcagttg ctgctgagcg gcatgagctg cgccagctgt gtcacccgcg tacaaaatgc
    12001 gctgcaaagc gtaccgggcg tcactcaggc acgggtaaac ctggcggagc gtactgcgct
    12061 ggtgatgggc agtgcctccc cacaagattt agtgcaggcg gtggaaaaag cgggctacgg
    12121 cgcggaagcg attgaagatg acgcgaaacg ccgtgagcgc cagcaggaaa ccgccgttgc
    12181 tacgatgaag cgcttccgct ggcaggcaat tgtcgcactg gcggtgggta tcccggtgat
    12241 ggtctggggg atgattggcg ataacatgat ggtcaccgct gacaaccgca gcctgtggtt
    12301 ggttatcggc ctgataaccc tggcggtgat ggttttcgcc ggcggccatt tttaccgcag
    12361 tgcatggaaa agcctgctga acggtgcagc gacgatggat acgctggtgg cgctgggtac
    12421 tggcgtggcg tggctctatt cgatgagcgt caacctgtgg ccgcagtggt tcccgatgga
    12481 agcgcgacat ctttattacg aagccagcgc gatgattatc ggtctgatca atctcggcca
    12541 tatgctggaa gcacgcgcac gtcagcgttc ttctaaggcg ctggagaaat tactcgattt
    12601 aaccccaccg acggcgcgcc tggttactga cgaaggtgaa aaaagcgtgc ctctggcgga
    12661 agtgcagcca ggtatgttgc tgcgcctgac gaccggcgat cgcgtgccgg tagatggcga
    12721 gattacccag ggcgaagcat ggctggatga agcgatgctg acgggcgaac caatcccgca
    12781 gcaaaaaggc gaaggcgaaa gcgtccatgc cgggacagtg gtacaggacg gtagcgtgct
    12841 gtttcgtgcc agtgcggttg gcagccatac cacgctgtca cggatcattc gcatggtgcg
    12901 ccaggcccag agcagcaagc cagaaatcgg tcagctggcg gataaaatct cagccgtatt
    12961 tgtacctgtg gtggtggtga ttgcgctggt cagtgcggca atctggtact tctttggtcc
    13021 ggcaccgcaa attgtttata ccctggtgat tgccaccacg gtactgatta tcgcctgtcc
    13081 gtgtgcgctg gggctggcga cgccgatgtc gattatttcc ggcgtcgggc gggcggctga
    13141 gtttggcgtg ctggtgcggg acgccgacgc gctgcaacgc gccagtacac tcgataccgt
    13201 cgtgttcgat aaaaccggga cgctgaccga agggaagccg caggttgtcg cagtgaaaac
    13261 gtttgctgat gttgatgaag cgcaggcatt gcgtctggcg gcggcactgg agcaaggttc
    13321 cagccatccg ctggcacggg cgatcctcga taaagcaggt gatatgcagc tgccgcaggt
    13381 caacggtttc cgcacattgc gcgggctggg cgtgagcggt gaagctgaag gtcatgcgtt
    13441 attgctgggc aatcaggcgc tgttaaatga gcaacaggtt ggtaccaaag ctatcgaagc
    13501 ggagattact gctcaggcat cgcaaggggc aacgcctgtg ctgctggcgg ttgacgggaa
    13561 agcggtagcc ctgctggcag tacgcgatcc attgcgtagt gatagcgtgg cggcgctgca
    13621 acgcctgcat aaagcgggat atcgtctggt gatgttgacc ggggataacc caaccactgc
    13681 caatgcgatc gccaaagaag ccgggattga tgaagtgatc gccggggtgc tgccggacgg
    13741 taaagccgaa gcgattaaac gcctgcaaag tgaaggacgt caggtggcaa tggtgggcga
    13801 cggcattaac gacgcgccag cgctggccca ggcggatgtc ggcattgcga tgggtggcgg
    13861 cagtgatgtt gccattgaaa ccgcggcgat taccctgatg cgccatagcc tgatgggcgt
    13921 tgcggatgcg ctcgcgattt cccgcgcaac gctgcgcaac atgaagcaga acctgctcgg
    13981 tgcctttatc tacaacagca tcggtattcc ggtcgccgcc ggtattttgt ggccgtttac
    14041 tggaacactg cttaacccgg tagttgccgg agcggcaatg gcgctctcgt cgattaccgt
    14101 agtgagtaac gccaaccggt tgctgcggtt taaaccgaag gaataagtac gtcattgcgg
    14161 atgcgctgct ttagggcggc gcatttggca tcgacgcatg actgccggat gcggcgtaaa
    14221 cgccttatcc ggcctacggt tcaggcacag gtttgtaggc ctgataagac gggtaagcgt
    14281 cgcatcaggc aatggtgctc ggatgccgga tgcggcgtga acgccttatc cggcctacga
    14341 gatgaagcga tgttttggcc ttacgcgacc ttttttgcac gctcttcacg gcgtgccaaa
    14401 tattcagcca ctgtttcaat ccgtcccaat tcttcctggg tgcgcatgtt gttttcaact
    14461 tcccaaagat caactgccgc ctggaggttt agcctaaaat cgactgtggt atcaaaaact
    14521 ttcgccagac ggaatgccat ctcagtggtg agtttacgat tgttattgat cagtgcactg
    14581 acgctattac gatgaacatg cagcaactct gctaactcat tgattttcaa atcgagcggt
    14641 tccagatatt catagagaag aatatctccg ggtgtcgtcg gttttcttgt tgcctgtttc
    14701 atggttttta actgttgctt ccctgtgaat agcgatgcaa gaacatactg aatcatacaa
    14761 acacattaaa caagtcccca actccatttg cgccatccct caccgcgcgc tagcatgata
    14821 tttcacaaag ggaggtcgta tggatctgtt gtaccgggta aaaacgcttt gggccgcgct
    14881 gcgcggtaat cattacacct ggcctgccat cgatatcacc cttcccggca atcgccattt
    14941 tcatctgatt ggcagtattc atatgggtag ccacgatatg gctcccctgc ccacccgttt
    15001 gctcaaaaag ctcaaaaacg ccgatgcgct gatcgtcgag gcggatgttt ccaccagcga
    15061 tacgcctttt gctaatttgc ctacttgcga ggcgctggaa gagcgcatta acgaggagca
    15121 actccaaaat ctgcagcaca ttagccagga gatgggcatt tctccgtcgc tcttttctac
    15181 tcaaccgctg tggcaaatcg cgatggttct tcaggcgacg caggcacaaa aactggggct
    15241 gcgggcagaa tacggtatcg attaccagtt attgcaggcg gcgaagcaac aacataaacc
    15301 cgtgattgaa ctggaagggg ctgaaaacca gattgccatg ttgctccagc tccctgacaa
    15361 aggactggcg ctgctggacg atacgctgac ccactggcat accaacgcac ggttgctgca
    15421 acaaatgatg agctggtggc tgaatgcacc gccgcaaaat aatgatataa cgctgcccaa
    15481 tacgttcagt cagtcgctgt acgatgtgct gatgcatcag cgaaatctcg cctggcggga
    15541 taaattacgc gccatgccgc cggggcgata tgtggtcgcg gtcggtgcac tacacctgta
    15601 tggagaaggg aatttgccgc aaatgttgcg ctaaaaaaat ggccaatatc gctattggcc
    15661 cgtcaaagag gaatttcatt tttttattat tatgccgtca ctttaagcga cggtgtaact
    15721 cgattgtcgc tcaatctcac catcctgcca atactcttag gcaagatgac tctttttttt
    15781 ggaccgccat caggcgtatg cttgcttcgt ttttttgttt aaggcaggaa aattaccatg
    15841 acacccgcag ttaaattact cgaaaaaaac aagatttcgt ttcaaatcca tacctacgag
    15901 cacgatccgg ctgaaaccaa ttttggcgat gaagtcgtca aaaaattagg tttgaatccg
    15961 gatcaggtct acaaaacgct gctggtggca gtgaacggtg atatgaaaca ccttgccgtg
    16021 gccgttacgc cggtcgcagg tcaactggat cttaaaaaag tagcaaaagc gctgggtgcc
    16081 aagaaagttg agatggccga tccgatggtc gcgcagcgtt cgacgggata cctggttggg
    16141 gggattagcc cactggggca gaaaaaacgt ctgccaacga ttatcgacgc ccccgcacaa
    16201 gaatttgcca ctatttatgt ttccggcggc aagcgcggac tggatatcga actggcggca
    16261 ggcgatctgg caaagatcct cgatgccaaa tttgctgata tcgcccgccg cgattaagca
    16321 ttgtgccgga tgcaaacatc cggcactttc ggattactgc cagctcacct cacctttcgg
    16381 ttcataaaca ctcacatcca gcggcgagct tttctggata tacgctttca gcacttcggc
    16441 atcaataaag ccggtattca catagcccgg tttgttatca aggcgcggat atccatcacc
    16501 gccggtggca ttgaagttta atgtcgccat acggtaagtt ttcgccggat cgaccggttc
    16561 gcctttgatt ttaaggtcgt tcagtttgcc gtctttcgcc acaaagctaa cgttggcaaa
    16621 ttgcgggtag gcacctgaat ctggcttcat ctgcgcgacg gcggtcaggt aatcaatcac
    16681 ctctttaccg gtcatgtcgg catacaccac cacattgccg aatggctgca ctttcagcac
    16741 gtttttatag ctgatatcgc ctgcttcgat agaatcacga attccgcctc cgctcatcac
    16801 cgcaaagtcg gcaccagtgc gatccatttg ggctgccaga atcaaccgcc ccatattggt
    16861 ctgtacaaaa cgcactttgt cacgatcgcc ttccagacga ccattggttt cgcctatttt
    16921 cacttccagc tgcgctttgc ctttgttctg gaacggtgat aacagcgaga tcatttgctg
    16981 gttttcagcg atttcaggag tgtaaagcac gcgctcgctt ttcccgtctt cccaggtcac
    17041 tttcttcttc aggttcaccg gaatcagctg gtagttaacc attttcattt cgccattacg
    17101 aaactcaaaa tcagcccgtc ccacgtattt gccccactca tgcgcctgca caatccagat
    17161 gccgttttgt tgatctggct tgcatggcgt acccggcacg taatcgacct gttttttgtt
    17221 ttctgccgcc atgcagaccg gatcttgcga gtgaccaccg acgatcatcg ccagcgatcc
    17281 ggcaggcagc gcgcgtgcca tctccacatc gcccggtgcg ttagagccgt gctcaccatt
    17341 atcgtaatgc cccatatggg tcgccgcgat aataatgtct ggcttttctg tctgttgcag
    17401 ctcctgaatc accagcttcg cttcatcggc gggcttacga aattcgacat cagtgaagta
    17461 ttccgggtta ccaatttttg ctgtgtcatc ggttgtcagc ccaatgacgg caattttcag
    17521 atcctgacgc ttaaacagcg cccacggttt aaacaggcgc tcgccagtac ttttctggta
    17581 gatattcgcg gaaagcaacg ggaacttggc ccacttttcc tgctggcgta atacggtgag
    17641 cggattatca aattcatgat taccgatcgc catcgcgtca tagcccacca gattcatacc
    17701 gcgaaaatca ggttcggcat cctgtaagtc agactcgggc acgccagtgt taatgtcgcc
    17761 accggaaagt agcagcacgc taccgccttc agccgcaacc tctttgcgga taccatccac
    17821 cagcgttttt tgcgccgcca gaccatattc gccatattca ttgcgccaaa aatgcccatg
    17881 atgatcattg gtatgcagaa ctgtaatttt gtaggtttta tcctgctcat acgccagagc
    17941 agtttcactc gccagtgtaa atgtggttaa cagcgctaac gccacgcccc gctgcaataa
    18001 tttcatactt ctctccctga cctgatttca acgtgttgaa aaatagtatg acgcgacatc
    18061 atagacaagt ctgcgtccgg tgaagataaa tctgcatcca gattagaaat tctgtattcg
    18121 gcgttgagac ttccttcagg cgacgcatac aggtatgtta gtcgggtaat aatcacaaat
    18181 aagatcattc tttacatcgc aaccctgaaa aagtgacttt cctatggcaa tgagtgaaca
    18241 accccagcct gtggcgggcg cggctgcgtc aacgaccaag gcccgaacat cgtttggtat
    18301 tttaggtgct atcagcctct cacatctgct gaacgacatg atccaatcgc tgattctggc
    18361 gatttatccg ctgcttcagt cagaattttc tctgacattt atgcagattg gcatgataac
    18421 cctcaccttc cagctcgcct cttcgctact gcaaccagtg gtcggctact ggaccgataa
    18481 atatccgatg ccgtggtcgt tgccaattgg catgtgcttt accttaagtg gtctggtgct
    18541 gcttgcgctg gcgggcagtt ttggcgcagt tctgctggcg gcggcgctgg tcggtaccgg
    18601 ttcatcggtc tttcatccgg aatcttctcg cgtagcccgt atggcttccg gcgggcggca
    18661 tggcctggcg caatctatct ttcaggtcgg cggcaacttt ggcagttccc tgggaccctt
    18721 gctggcggcg gtgattatcg cgccttatgg caaaggcaac gttgcctggt ttgtgcttgc
    18781 ggcactgctg gcgatcgtgg tgttggcgca aattagccgt tggtactcgg cacagcaccg
    18841 aatgaataaa ggaaaatcca aagcgacgat aatcaatcca ctgccgcgca acaaagtggt
    18901 actggcagtc agcattctgt taatcctcat tttctcgaaa tatttctata tggcgagcat
    18961 cagcagctat tacacctttt atctgatgca aaaattcgga ttatctatcc agaatgccca
    19021 gcttcatctg tttgccttcc tgtttgccgt tgcggcaggt acggtgatcg gcgggcctgt
    19081 aggggataaa attgggcgga aatatgtgat ttggggctct atcctcggcg ttgcgccgtt
    19141 tacgctgatt ttaccctacg ccagcctgca ctggacgggg gttttaacgg tgattattgg
    19201 atttatcctc gcttcggcat tctctgccat tctggtctac gctcaggagc tacttccggg
    19261 acgtatcggt atggtttctg gactcttttt cggttttgct tttggcatgg gaggtctggg
    19321 agcggcagtt ctggggctta tcgccgatca caccagcatc gagttagtct ataaaatctg
    19381 tgctttcctg ccactattgg ggatgttgac catattcctg cctgataacc ggcataaaga
    19441 ctgatttcat tgcagccaaa ggcaaacttt ggctgcatcg ttttacagtc gccataagcc
    19501 tttcctctgt taaaccgcct tctgttttcc gatccgtgct ttttttgcag ctaattccat
    19561 ttttctgcaa aattcaataa ttattcatga acatcatcaa tgaaattgtc ataaactatt
    19621 acctgtaatt ttggttttcc cggccaaaaa tggacaataa ccaccaggaa aaggagacgg
    19681 aatgcatcac gccaccccgc ttatcaccac cattgttggc ggccttgtgc tcgcctttat
    19741 cctcggcatg ctggccaata aactacgtat ttctcctctg gtgggatatc tgttagcggg
    19801 tgtgctggca ggaccattca ctccgggctt tgttgccgat accaagcttg cgccggaact
    19861 ggctgaactg ggcgtcattc tgttgatgtt tggcgtcggt ttgcactttt cgctgaagga
    19921 tttgatggcg gtaaaggcca tcgccattcc cggtgcgatc gcccagatag ccgtggcgac
    19981 gctgctgggt atggcgctct ctgccgtgct gggctggtcg ttaatgaccg gtctcgtgtt
    20041 cggtttatgt ctttccaccg ccagtaccgt ggtgttactg cgcgcacttg aagaacggca
    20101 attaattgac agtcagcgtg ggcaaatcgc catcggttgg ttgattgtgg aagacctggt
    20161 aatggttctg acgctggtgt tgctgcccgc agtggcagga atgatggaac agggcgatgt
    20221 gggctttgcc actcttgcag tcgatatggg gatcaccatc ggcaaagtga tcgcatttat
    20281 cgccattatg atgctggtag gtcgccgtct ggtgccgtgg attatggcac gcagcgcggc
    20341 aaccggttct cgcgagctgt ttaccctgtc ggtgctggcg ctggcgttag ggattgcctt
    20401 tggtgcggta gagctgtttg atgtctcctt tgcactcggt gcgttctttg ccgggatggt
    20461 actgaacgag tctgaactga gtcaccgtgc cgcccacgat acgctgccat tgcgcgacgc
    20521 gtttgcggtg ctgttttttg tctccgtcgg gatgttgttt gatccgttaa ttctgattca
    20581 gcaaccgctg gcagtgctgg cgacgctggc gattattctg tttggtaagt cgttagccgc
    20641 atttttcctg gtgcgactgt ttggtcactc ccaacgtacg gcattaacca tcgccgccag
    20701 cctggcgcag attggtgagt tcgcgtttat cctggcggga ctgggaatgg cattgaattt
    20761 actgccgcag gccggacaaa acctggtact ggcaggggcg atcctgtcga ttatgctcaa
    20821 cccggtactg ttcgcactac tggagaaata tctggcgaag accgaaacgc tggaagagca
    20881 gacgctggaa gaggcaatcg aagaagagaa acagatccca gtggatattt gcaaccatgc
    20941 gctattggtg ggttacggtc gtgtaggcag cctgctgggg gagaaattgc tcgcctctga
    21001 tattccgctg gtggtgattg agacgtcacg aacccgtgtt gatgagctgc gagagcgtgg
    21061 ggtccgcgct gtattgggca atgcagcgaa cgaagaaatt atgcaactgg cgcatctgga
    21121 atgtgcaaaa tggctgatcc tgacgatccc caacggttat gaagcgggtg agattgtggc
    21181 gtctgcccgc gcgaaaaacc cggatattga gattatcgcc cgcgcccatt atgacgatga
    21241 agtgacgtat atcaccgaac gtggcgcgaa tcaggtagtg atgggtgaac gtgaaattgc
    21301 ccgtactatg ctggaactgc tggaaacgcc accggcaggt gaagtggtga cggggtaaac
    21361 ggtggttgcc ggatgtaaaa tatgaaaaat atgtaggcat gataagacgc gccagcgtcg
    21421 catcgggcat cgagagccaa atgccagatg cggcgtgaac gccttatctg gcctacgaac
    21481 cgacgataac ttaacgatcc cagtaagact cttccaggct gtcttcacgc tccggcaagc
    21541 cgcgcgttaa acgaggtgaa tgctggttca gtacctgata gctcacacgg ttagcatatt
    21601 tacacacctg cgctaacgat gaataagtta accaggtgaa tttatgtttg ctggagtttg
    21661 gtacgttgct acgatggtag ctgttggcgg taatgtcatg cagcaacgct gccaatgcgc
    21721 catcccccgc tccattagtg ttcatgattt tttccggccc gcccatgtac ggcgcaatgt
    21781 gcgaatatac acgcagcgga ttctggcaat ccttgtggcg catggcgcgg ctaaactcat
    21841 actggttgaa ttccgctata gcgcccggca gcagcggatg ctgggtttta cgtttcgctt
    21901 cgtcttcggt aaagcccgcc atatacaagc cgattggccc ggcggtgcac agcaccagat
    21961 ctacccagtc cagcgccttg tcagatgcca acaacggatc gctttctccg gtcaacgctt
    22021 cggcttcatc ttcgttcatc gcaaggatag aaacgtggtc tttgaggaat tgctgccacc
    22081 actgcggatt ctcggcaatg acaaacttgg tgcccagcgt cagcaccacc ggtacgttat
    22141 atttcttcgc gtactcaatg gctttcatgg ttgcttccgg catgggttca cccggtttgc
    22201 aacgcaccag ataagaggtg agaaccagtg ccgaggctcc ggcaatcaca tcttccggaa
    22261 tgctttcagc ccgcagctgg ttcatgtggc ctggactgat agcaaaggta cgttccccgg
    22321 actcgccaat cagcgtaaag caacgaccaa tcgggccatc cacgccttgt agatagttaa
    22381 gatcggtacg gctggaagtg ttacacaggt aacgataggc ataactgcca atttcaatat
    22441 tgctgcacat gacgcccagc agcaccgaac ggtcgtccgc gagcaccgag tagttgtgca
    22501 tggtgttacc aatggtgcca cccgcaaact gatgggtaat caggtttttc tgttttagct
    22561 cctgataaag cgcttcggct acgtcatcct caatcaccag tgaatgcccg gcgcttaatc
    22621 cataacgctc aatgaattca tcatccactt tcgcttcaat atcgaccagc gtctggtcaa
    22681 tacctacgac ccaggcggcg ctggtttcgt tttctggctg gaattgctga agcagcggat
    22741 cgcgtgcatt tacagggaag taatgtttgg atttacgttt accgggaaat ttcatggttg
    22801 tttttacggg tggttaactg agcggcgaat gttaacacaa tctgacggga gcgcgcgaga
    22861 cgcagccagt ttcaatatca gcaggcggga tcgcattttc atggcagtgg ttccttacaa
    22921 tgacgtaatt tgaaaggagt ttttgtatga agccggaaaa caaactacct gttctggacc
    22981 ttatttctgc tgaaatgaag accgttgtga atactcttca gccggattta ccgtcctggc
    23041 ccgcaacggg aacgattgct gagcaacgac agtattacac gcttgagcgc cgattctgga
    23101 atgcgggcgc tccagaaatg gcaaccagag cttacatggt tccaacaaaa tatgggcagg
    23161 tggaaacacg tctcttttgt ccgcagccag atagcccggc gacgctattt tatttgcatg
    23221 gaggcggttt tattctcggc aatctcgata cccacgatcg catcatgcgc ctgctggcaa
    23281 gctacagcca atgtacggtg attggtattg attaccccct ttcacctgaa gcgcgttttc
    23341 cgcaagcgat agaggaaatt gtggctgctt gttgttattt ccaccagcag gcggaggatt
    23401 atcaaatcaa tatgtcccgc attggctttg ccggtgattc cgcaggtgcc atgctggcgc
    23461 tcgccagtgc gttgtggttg cgtgataaac agatcgattg cggtaaaatt gcgggtgttt
    23521 tgctgtggta tgggctttac ggattacggg attccgtgac tcgtcgtctg ttgggcggtg
    23581 tctgggatgg cttaacgcaa caggatttgc agatgtatga agaggcgtat ttaagcaacg
    23641 acgcggaccg cgagtcaccg tattactgtc tgtttaataa tgatctcact cgcgaagttc
    23701 cgccctgttt tattgccggg gcggagttcg atccgctgct ggatgacagc cgtctgcttt
    23761 accagacgtt agcggcgcat cagcagccct gtgagttcaa actctaccca ggtacgctgc
    23821 atgccttttt gcattattca cgaatgatga aaaccgccga cgaggctctt cgcgacggcg
    23881 ctcagttctt taccgctcag ctttagcgat acgcggcaac aagattagcc atcatttcga
    23941 tatgttccgg cgtggcatta agcgctggaa tatattcata ttttttcccg ccggcaccga
    24001 ggaagacctc acggttttgc tcggcaatct cttccagcgt ctccagacaa tccgcagcaa
    24061 agcccgggca catcacctgt atatgaccta cgcctttttc tccgagcatt ttcagcgttt
    24121 cgtcggtata aggcatcagc cagggttccc ggccaaagcg cgactgaaag gtcatcatca
    24181 ctttttccgg tgccatcccc agtgcggaag ccagttcgcg agtcgttgtg cggcaacgtt
    24241 gcgggtaatc atcgccttca tctgcataac gctggggaat gccatgataa gagagcagca
    24301 gcagatccgg ttcgccatgt ttggcaaaag aagcgcgtac gctgttcgcc agtgcattaa
    24361 tgtaatcgtg gttatcggcg taatcacgaa taaacgatat ccccggaatg ctacgtttgc
    24421 gcgccagaat gcgtgccagt tcatcccata ccgcaccgac cgtagaacag gagaattgcg
    24481 gataaagcgg cagcaccaca atatgatcta catgctctgc caggagttca tcgacggcgc
    24541 tttccagtga tggcgagccg tagctcatgc ccagcgctac gggcgtctcc ggtaaacgtt
    24601 gtgccagcgc ctgctgttgc tggcggctgt aaaccatcag cggcgagccg tcttccatcc
    24661 agaccgaggc gtacagcttc gccacacgcg gcgagcgcag cggcaaaatc acgccgcgca
    24721 gcaacggcca ccataacaac cgtgaggtat caaccacgcg tctgtcgctt aaaaattgtt
    24781 tcagatagcg ttttaccgct tcaggtgtgg gggcatcggg cgtacccagg tttgccagca
    24841 ggataccggt tttagtctga cgcattaccg cctcttatcg attcaacttg ttgataattg
    24901 tagcggaaaa gtgaggaaga agaactaatt gctgtgagag gtcaaatcag aaaaaggaat
    24961 agcgcagatt gaggtttttg taaaaggccg aatgaatatc cggcctgaga ttgctgataa
    25021 gtttgcttgt gcgggcctgt tcccctcacc ctaaccctct ccccgagggg gcgaggggac
    25081 tgtccgtgcg cgctttcgaa ttagccgagg attttttcca gatcagcgcg aacttcagca
    25141 accggcttgg tgccgtcaac tttcgcgtat ttggtgttac ccgcttccgc ttctttggag
    25201 tagtagccga tcagcggtgc agtcatctga tggtattcaa ccagacgttt acgcacggtt
    25261 tcttcctgat cgtctttacg ggtagtcagt tcttcaccgg taacgtcgtc tttgccttct
    25321 actttcggcg gattgaattt aacgtgataa acacgaccag acggcgcatg aacgcggcgg
    25381 cctacgatac gatcaacaat cagttcgtcc ggtacgtcga attccagaac gtaatcaaca
    25441 ttgatgcccg cttctttcat cgcgtctgcc tgcggaatgg tacgcgggaa gccgtccaac
    25501 aggaaaccat tacggcagtc ttcctgagca atgcgctctt taaccagcgc gatcaccagt
    25561 tcgtcggtga ccagtttgcc agcatccata atgtcttttg cttgtttacc cagctcggag
    25621 ccagatttga ccgcagcacg cagcatatcg ccagtggaga tttgcggaat accatatttc
    25681 tccatgatga actgagcctg agtccctttc cccgcgcccg gagcgccaag cagaatgata
    25741 cgcattgcga aaatcccctt aaaatgtgtc gaattttttg aaaaagcgat aaacgatacc
    25801 accaacaggc gattgcctca agaaaggcac ctgaggctga aacggttaat ggcgagataa
    25861 tttgcggaaa gtgcagatga tgaaaagaaa aatgccggat gacacaaagg tcatccggca
    25921 tgacatcagg aaaccagcag ctggttcata cgacgaataa acaggttcgg atcttccagc
    25981 gtgccgcgtt ctgccagcag cgcctgatcc agcagcagtt ctacccactc gctgaacttc
    26041 gcttcatctt cagtatctgc cgcacgtttc accagtacgt gatccgggtt cagttcgaag
    26101 atgtatttca cttctggcac tttctggccc gccgcagcga acagtttcgc catctgagtg
    26161 ctcatttcgt ccgcgtcggt cgaaacgatc gctggcgtat cggtcagacg gtgagtcaga
    26221 cggacatctt tcacgcgctc gccgagcagg gctttcacac ggtcgatgaa cggagtcagt
    26281 gctttctccg cttctttcgc gctctcatca acttcgtcag ccagtttttc cagcgactcg
    26341 tcaactttag acaccgactg gaacggttta ccgtcgaact cagtcagata gttcatcatc
    26401 cactcatcga tgcggtcgga aagcagcaga acttcgatgc ctttcttacg cagcagttcc
    26461 aggtgcgggc tgctcttcgc tgccgcatag ctgtctgcag tgatgtagta gattttctcc
    26521 tgcccttctt tcatgcggga aacgtagtct tccagagaca cggtctgcgc agaagaatcg
    26581 gtataagtag aagcaaaacg cagcagtttg gcgatcgctt cctggttagc gaaatcttcc
    26641 gccggacctt ctttcagtac caggccaaac tgttgccaga aggtctggta tttgtccgcg
    26701 tcgtctttcg ccagtttttc cagcatttgc agcacacgct tggtcagcgc attgcgcagg
    26761 ttacgcgtta ccgtgctgtc ctggaggatt tcacgggaaa cgttcagcgg cagatcgctg
    26821 gagtcaatca gaccacgcac gaagcgcaga tagttcggca tgaactgttc tgcgtcgtcc
    26881 atgatgaaca cacgctggac gtacagtttc aggccgtgtt tatgatcacg gttccacata
    26941 tcccacggag cctgggacgg gatgtacagc aggctggtgt actcctgctt accttcaacg
    27001 cggttgtggc tccaggtcag cggatcatta aagtcgtggg cgatgtgttt gtagaactct
    27061 ttgtactctt catcggtgat ttccgacttg ttacgagtcc acagcgcctg cgctttgttg
    27121 attttctccc aggagataac ggtttcgccg tctttctctt cgcgtttttc gatctctacc
    27181 ggcagcgcga tatggtcgga gtatttgctg atgatggaac gcacgcgcca gtcatcgagg
    27241 aactcgtctt cgccttcacg cagatgcagg gtgatttcag taccacgatc ttctttggtg
    27301 atgtcggcaa cggtatattc accttcgcca gccgattccc agaagacgcc gttttctggt
    27361 ttttcgcctg ccgcgcgagt acgcacggtc actttgtcgg ccacgataaa cgcagagtag
    27421 aaaccaacac caaactgacc gatcagctgg ctgtctttcg cctggtcaga acccagggat
    27481 tcgaggaatg atttggtacc ggatttagcg atagtcccca gatggtcaat cacttcgtcg
    27541 cgggtcatcc ccacgccgtt atcggagatg gtcagcgtgc gcttgtcttt atcgaaagag
    27601 acacgaacgc gcagttcgcc atcaccttcg tacaggtccg ggttagatag cgcacggaaa
    27661 cgcagcttgt ccgccgcatc ggaggcgtta gagataagct cacgcaggaa gatttcttta
    27721 ttggaataga gagaatggat catcaggtgc agaagctgtt tcacttctga ctgaaaacca
    27781 cgagtttctt gtcctttcat gtaggtctac ctcaataatg ccattttaag gttaaaaaca
    27841 ggatgaggga gagatgggga caagggagaa taatttcaag cgagagcagg tgatcctgct
    27901 ctcgtttgct taaaaacgaa tcttatgacg cccggcaagg gagtgtgaca gcgtggtgcc
    27961 atcgaccatt tccagttcgc cgccaaccgg tacgccatga gcgattcggc tggcttccac
    28021 gtcatattgc gcgcaaagct cggcaatgta gttagcggta gcttcacctt caaccgtggg
    28081 attggtggcg aggatcactt cagtgatttt ttcctctgcc agacgctgtt ccagacgatc
    28141 aaggccgata tcatccggac cgatgccgtc cagcggtgac aggtgcccca tcaacacaaa
    28201 ataacggcct gaaaactgcc ccgtctgctc aatggcgtag atgtccgccg gactctccac
    28261 cacacagatt tgaccgtttt cctgacgacg cggattcgaa cagatgttac agacttcctg
    28321 ttcggtgaaa gtgcggcaat cggcgcagtg gccgatttcc gacatcgccc gggtgagcgc
    28381 ctgcgccaga cgcatcccgc cgctacgatc gcgctgaagc agcgtgaacg ccatacgctg
    28441 cgccgacttc gggccaacgc ccggcagaca gcgcagtgct tccataagct gtgttaacag
    28501 cgggctggtt tgcatcagaa cggcatctta aagccaggcg gcagctgcat tccggaggat
    28561 acagaggcca ttttttcttt ctgcgtttct tcaatacgac gtgctgcgtc gttgaatgct
    28621 gcagccacca ggtcttccag catctctttg tcgtcttcca gcaggctcgg gtcgatctct
    28681 acgcgacggc agttgtgtgc accgttgatg gtcactttta ccagacctgc gccagattcg
    28741 ccggtgactt ccagctgcgc gatctcttcc tgcattttct gcattttttc ttgcatctgc
    28801 tgggcttgct tcatcaggtt acccagaccg cctttaccaa acataggttt ctctctcaat
    28861 cacgttaagg atgacgaacg taagctgtgc ttacgatcaa atggggcgga tactttcttc
    28921 atccagctcc gcatcgaaga accgacgcag ggtctgaata ttattatccg caataatgga
    28981 ctcgcgcgcc tgcgcaagtt tttcttcgta tatcgcctga cgccactcca gcggcgtacg
    29041 caccgcggga ttatcatctt caacgatagt cagttcaacc gttgaacctt ttaacgtgct
    29101 caacgcttca gccagttttt gctgtgcacc gcggttgttc aaatgccgct gagaggagcg
    29161 caaatgcaga catactgcgt tgtcgctctc ctctttccag gcatttaagg ccacctgttc
    29221 gaccagtttt ggtagcgaaa gttgactcac ctgtgccgcc cacgcgtcgc gctcaatggc
    29281 ttctgccgcc agcttcgccg ccagttccgg cgttttttca tgttccagcg cttttttcag
    29341 cgccttcggc gtggcgacca cttctttttg ctgcatcact ggagtggtag ccttccagcg
    29401 atacgcttct tttttggctg gcgctttttc cagcgccgat ggcaccggac gcgcctgaac
    29461 gcgatcggtg accgaagcca gtctttccag cgcagcgtta ttcaccggcc gcgcgcgggt
    29521 agcggctgcc ggttcactct tttttgcttt ggttgctccc tgcacgcgct gcaactgctg
    29581 gcgcgccgcc agcacctggc tggtggtttc cgggagcggt acagtcggtg cctgctgcgg
    29641 cgctgattgc ggttgcggcg gcacctgggt tggcgtcatt actgccgttg gcgcgacggg
    29701 cgcaaaggac tggcgtggca cttctggctc aggcagaggc atacgtggat ggaacgccag
    29761 cgcgcgcagc agcgtcatct caacgcccat gcggcggtcc ggcgcatacg gtaattcttt
    29821 gcgaccaatc aacagcgtct gatagtaaag ctgaatatcc gtcggcggta tggtgcgcgc
    29881 cagttcacgc atccgcagct caatggcggc catgtcgttg ccaagtgcag caggcgaaag
    29941 ttgtaccatc gcaatacgat gcaacaggcc gagcatttcc accagcaacg cttcccactc
    30001 gataccacgg gcagcggctt cattaatcag cgccattacg cgctcgccgt tggcctcgac
    30061 catcgcttca accagcgaca gcgcctgatc gtcgtcaagc gtacccagca tcgcactgac
    30121 tgcctgggtt gaaacctggc cgtcaccgct ggcaatcgcc tggtcggtca gacttaaggc
    30181 atctcgcagg ctgccttcag cggcgcgcgc cagcaattgc aacgcccgcg gctcgtgagc
    30241 gatatgttct tcgttgagga tgtgctcaag ttgatggcga atttgctcga catccagcgc
    30301 cttgagatga aattgcaaac agcgcgacaa aatcgtcacc ggcaatttct gtggatcggt
    30361 cgtcgccagc agaaacttaa cgtgctccgg cggctcttca agggttttta acagtgcgtt
    30421 aaagctgtgg cgcgacagca tatgcacttc gtcgatcaga taaactttga aacgaccacg
    30481 cgccggagcg tactggacgt tatccagcag gtcgcgggta tcttcaactt tggtgcgcga
    30541 ggcggcgtcg atttcaatca gatcgacaaa gcgcccctgc tcgatttcac gacagttatc
    30601 gcacacgccg cacggcgtcg cggtaatgcc ggtttcgcag tttagcccct tcgccagcag
    30661 tcgggcgata gaggtttttc cgacgccacg ggtaccggaa aaaagataag catgatgaat
    30721 acgccctaac gacaagccgt tcgccagtgc ggtcagcaca tgttcctggc cgacgacgtc
    30781 agcaaaggtt tgtgggcgcc attttcgggc taagacctga taactcattg gcaggctctg
    30841 aaacgctgga aggtggattc acgaaggggt aatgctaaca cagccccgtc agaacggcga
    30901 ggctgaatgc acatcttgtg ctgtccgtag cgtgggcagc acaagactgg cgataattaa
    30961 tggcccggga acgggacaag gctgtagctg gtaatgccct gtttttcgag acgctgttcg
    31021 ccgccgagat cgaacaggtt gataatgaac gcagcgtcag ccacttcacc acccagacga
    31081 cggatcagtt taacggtcgc ttcgatagtg ccgccggttg ccagcagatc gtccaccacc
    31141 agaactttgt cgcccggttt gatggcatca acgtggatct ccagctgatc ggtgccgtat
    31201 tccaggtcgt aagtttcact gatggtttca cgcggcagtt tgcccggttt acggaccggt
    31261 acaaagccaa cgcccagacc cagagctacc ggagcgccaa acaagaagcc acgcgcttcg
    31321 gtgccgacaa ctttggtaat gcccgcattt ttgtaacgct caaccagcaa gtcgatgctg
    31381 agagcgtaag ctttcgggtc ttccagtaag ctggtgacat cgcggaaaag aatgccgggt
    31441 tttgggtagt cctgaatgct tttgatgcta tttttgagat actcaagctg ctgtgcagtc
    31501 gcggtcataa gtgtatgcct gcttgttacg gtggtactca cggcgcgttt taaacgtatc
    31561 aaaaataaca gttgtttaac ctttgaccgc ctgcgcctgt gctcgaaaac gccagaatgt
    31621 actggctgta cgcaataatt gcaactgcga ttgttgtgct tcagtgcttt tcttgctttt
    31681 catcaatcac cggaattcgc cacatataga aaagcaaaca ggcgagaatt accagcaaca
    31741 tgatgcgcac ccatggcatc tggacgaacc acagagaaat ggcaaacgtg agcaaaataa
    31801 gcaaaatcgc ccgcggtttg acgccgcgcg gcatcgcatg atgtttctgc cagaaacgta
    31861 gatagctgcc aaaccatgag cggtacagca accaggcgtg aaagcgcggg gaagaacggg
    31921 caaagcacca ggccgccagc aggataaacg gcgtcgtcgg taataccggt aataccacgc
    31981 ccagcgtacc cagcactacc gccagccagc caatgatgat taaaatgatt cgttgcatat
    32041 tgagtgttgt cagcttacag agtggctact ttagcataac aattatcatt ttcattgagg
    32101 tcttatcgtg aaaaccgccc tgctcctgga aaaactggaa ggacagctcg ctacgctgcg
    32161 tcagcgttgt gccccggtag cgcaatttgc cacgctaagt gcccgttttg acagacacct
    32221 ttttcaaacc cgtgcgacaa cactgcaggc ttgtctcgat gaggcgggcg ataatctggc
    32281 tgcgcttcgt catgcagttg agcagcaaca gctgccgcaa gtggcctggc tggcggaaca
    32341 tctggcggca caactggaag ccatcgcgcg tgaagcctcc gcctggtcat tgcgcgagtg
    32401 ggacagtgcg ccaccgaaaa ttgcccgctg gcagcgtaaa cgtattcagc atcaggattt
    32461 tgagcggcgg ctacgtgaga tggttgccga acgcagagcc cgcctggcgc gggtgaccga
    32521 tctcgtggaa cagcaaacgc tgcatcgtga agtggaagcc tatgaagcgc gcctggcacg
    32581 ctgccgccat gcgctggaaa aaatcgaaaa caggctagcg cgcttaaccc gctagcaatg
    32641 gagagagtat gtcactggaa aatgcccctg acgatgtcaa actggctgtc gatttgattg
    32701 tgctgctgga agaaaatcag atcccagccc gcaccgtgct gcgcgcgctg gatattgtaa
    32761 aacgcgatta tgaaaagaaa ttaacgcgcg atgatgaggc ggaaaagtga gaaataaatg
    32821 gggccgctaa atgtccccta agattgtggg caaacgcaaa actgcctgat gcgctacgct
    32881 tatcaggcct acaccgctcc tgcaatacat tgaattcttg cggtttcgta ggccggataa
    32941 ggcggtcacg ccgcatccgg catgaacaac gcgcactttg tcagtaatct cggggcaact
    33001 aaatgtcgcc ccctttggtt attaccctac cgctggcgtc gggtcatcgc ctttgtagtc
    33061 gcgtttgact tccgtcacct catcgccctt ctcgttgtgc agatgcactt caagctggtt
    33121 aaaggcaatg ttgatgtcgt tttcacggca cagctgatcg atagtacggt tcagctcatc
    33181 gacagtacga ctacggtcac gcagttcacg cacatacaga cgcagctcat gatccaacgt
    33241 gctggcacca aacgccgtaa agaagacttc cggcattggt tcgtgcatca cccttgggtg
    33301 ctcagtcgcc gccttcagta acactttacg cactttttcc agatcggagc cataggccac
    33361 gccgagacgg atcaccagac gcgtagtagt gtcagtcaac gaccagttga tcagacgctc
    33421 ggtaacaaac gctttgttcg ggatgatcac ttctttgcga tcgaaatcgg taatcgttgt
    33481 cgcacgaata cggatcttac ttaccgtccc cgagaagcta ccaatggtta ccgtatcgcc
    33541 aatacgcacc ggacgttcga acagaatgat caaaccggag acgaagttac cgaaaatttc
    33601 ttgtaaacca aaaccaagac ctacggataa tgctgcggcc agccactgga gtttatccca
    33661 agagacgccc agcgatccga acaccgtcat cgcaccaacg gcaataatga tgtagttaag
    33721 gatggtagta atggcatacg acgcgccctg acgcatattc agtcgcgaga gcaccagcac
    33781 ttccagtaaa ccaggcaggt tgcgaatcaa cgcccaggcc accattgagg cgataatcgc
    33841 aaacaacaga ctgcccatgg tgacgttttt caccaccgca gcgccagctt cagtgccgtt
    33901 gtaatgccag agcgtgatgc tgtcgagata gctgaacacg gtgatcaaat cggaccaaat
    33961 tgcccagaac atgacaccga acagcgcaaa catcagcaac atggtaatac gcagcgtctg
    34021 ctggttaacc tgttccagtg caatggtggg ttcttccggc ggttcggcac cttctgcgcc
    34081 ctctttcacc agattctgcc gacgcgccag cgcacgacgc caggcgatac gccgcgccgc
    34141 tacgcttaag ccgcgcaata ccgtctggta gagcaagttc cagatgatca ccagataaac
    34201 ggtttcaatc caacgcccgg agaggcgcag cgtggtgtag aaataacccg tggcagtcag
    34261 caccatcaat gcaatcggga taatcgacag cacggtaatg gtgaccagtc gcatggtgtg
    34321 cgactcttta tcacgccagc tttcgcggca cattggccat accaggaagg caatcagcag
    34381 caggttgaag aaaatcatcg cctgccccag cacatcatcc atcagatgca gcggggaaag
    34441 ttctgccacc acagaccaga aatggatagg cagcaacgcg agactgatgc ggacaatttg
    34501 ccgacgccag tggctggtct gctgctccgg catgccgaag tgacgcacgg caacgccatt
    34561 tttctccagt accttccagc acaggccaaa caccagccag aaaatcgcca gttttttact
    34621 gaacgaccat agcagttcgc tgatgttgag ctgcatggtc aacagaatca ggccaaccgc
    34681 gagaataatc aggcacaccg gcagcgcgcg gatcaggtcg ataaggatcg cttttggtgt
    34741 gttgagctgg ctatcgttac gcagggaacc cacagcggaa gccagtttct gttgatacgc
    34801 tttcagccag cccagacgcc agtggatcag cccggcaatc aacagcagcg gcaaaccggc
    34861 gaggaaagcg ataaaaacgg caggccaggc tttttcccag ttcaccgtga ttttcatcga
    34921 cttaaattca tctttcaggc tttgcgggaa cgctttgatc cagtcccagt ccattggacg
    34981 gttactgttc acccaaaaga tttgctgagt caggatggat ttcaggtttt tcgatacgct
    35041 cattaactgc tgctggttga tttgcaggtt aatggccatc atcagctggt tacccaactg
    35101 tttgttgagt tgatccagca attcgcgacg catatcaacc acttgcaata acgcatcgtg
    35161 aacttcgctg ttgacttcgt tggtgtgacc ttcttccagt ttgttgacga acgcatcgct
    35221 ctggaagagt gcatcacgct gctggttaac ttcaaactgt tcgagacgca aatccgcgat
    35281 gcggttggtc atgttttcca gttcatccgc cgagggcagc gtttgttgtt gctggtaaag
    35341 gatacgagac aacagcaggc tgcccttcag gacggcaatc tgctctttaa tattgcgttc
    35401 cgattgcagc gcccgctcca gccagttttt gactttaatg ttttgctgca tcaactgatt
    35461 accgttttca gtcgcggtaa tcagacgctg acttaactgc tggttaattt ccagttcctg
    35521 tttcaccagc ggattagcct gaatacgcgc ggcttcatcc ggggagacgg cttcctgcgc
    35581 cgttttttca gttaaagtca ggcgcttgct gtttaccgct tcttgcaaca gctgcaactg
    35641 gtgctccaga cgggcgctgt tcgccgtcac gtaatcacgt tgcttttgca aggtatcctg
    35701 caagacggtg ttcccttcca ggcttttacg ctgctggtca atctccgcat tcagcaacgc
    35761 ctgctgagcc tgcattaaca ctttctggct gggacgtaag gcagtctcgc cgacatcagt
    35821 cccatccaga cgactgcgaa tttgttgcag ctgctgcgaa gcgttataca tcgcattttg
    35881 cacgcgttcg ggctgcgtct gtaacgaaac cagctggctg ttataagacg ccagatcgtt
    35941 ttgtgcgttt tgcaaatcgt ccagcgcctg ggcaacgcga gtttccagct ggcgcaacga
    36001 aagcgtactc agaattttgc gcgtttcttc gtcgttatcg acatcgctaa gtgctgttaa
    36061 cgccgcggtc gcctggcgca ttttttccgg cgcttcagcg actttttgcc gtagctgaac
    36121 tgtctcttct tttatgcgat cgattttatc gagggtggct aatgtatctg tcagatcctg
    36181 ctgcaccagt ttgtcctgag cagaaagatc tttttgttta tttagtgagt caagttgcgc
    36241 ctgcaggtcc gcttttgtcg gcagatcacc attcgatgac gcccgcgcaa acgccgtgtt
    36301 ctggcataac aagacaaaaa caaaagcaat aaatgctgaa aaaacaaaat gccgtgatcg
    36361 tttgtaatac tggaacatag tcatgatgaa tgaaggtttc tgaacctgaa gaacgacctg
    36421 aaaaagtcaa accgcaagaa tatcacgacg cagtgaacca gaatagcaac gacgaaaatg
    36481 tccaggaaaa atcctggagt cagattcagg gttattcgtt agtggcagga ttacgaagcg
    36541 tggggcacag gagatacatc tccagtaaga tggcgacgta atcgcgggct tcttttttaa
    36601 gatcaaaaga ttgcggggca aagagccagt tttccatcag gccggaaata tagccgcgca
    36661 taataattgc tgcccgacgc gtcattaaat ccgcaggcaa cattttcgct tcaatacaat
    36721 gttttaacgt ttgttctata cggtcataac tttccagaca gagattacgt tgtgcctgtt
    36781 gcacaacagc catttctccg acaaattcgc atttgtggaa tataatctcc atcaataatc
    36841 gacgccgttc ttctgtcacc gtggattcaa gaacatgaat taatatctct cttaatactg
    36901 agagtggatc gccagggaat tttgcctgat actcaagctc tagttcacca atattggatt
    36961 ctgacagttc ccagatctca ctgaacaaat ccgacttgtc tttaaaatgc cagtagattg
    37021 caccgcgcgt aacgccagct gcttttgcaa tctcgcccag cgaggtggat gataccccct
    37081 gctgtgagaa aagacgtaga gccacatcga ggatgtgttg gcgcgtttct tgcgcttctt
    37141 gtttggtttt tcgtgccata tgttcgtgaa tttacaggcg ttagatttac atacatttgt
    37201 gaatgtatgt accatagcac gacgataata taaacgcagc aatgggttta ttaacttttg
    37261 accattgacc aatttgaaat cggacactcg aggtttacat atgaacaaaa acagagggtt
    37321 tacgcctctg gcggtcgttc tgatgctctc aggcagctta gccctaacag gatgtgacga
    37381 caaacaggcc caacaaggtg gccagcagat gcccgccgtt ggcgtagtaa cagtcaaaac
    37441 tgaacctctg cagatcacaa ccgagcttcc gggtcgcacc agtgcctacc ggatcgcaga
    37501 agttcgtcct caagttagcg ggattatcct gaagcgtaat ttcaaagaag gtagcgacat
    37561 cgaagctggt gtctctctct atcagattga tcctgcgacc tatcaggcga catacgacag
    37621 tgcgaaaggt gatctggcga aagcccaggc tgcagccaat atcgcgcaat tgacggtgaa
    37681 tcgttatcag aaactgctcg gtactcagta catcagtaag caagagtacg atcaggctct
    37741 ggctgatgcg caacaggcga atgctgcggt aactgcggcg aaagctgccg ttgaaactgc
    37801 gcggatcaat ctggcttaca ccaaagtcac ctctccgatt agcggtcgca ttggtaagtc
    37861 gaacgtgacg gaaggcgcat tggtacagaa cggtcaggcg actgcgctgg caaccgtgca
    37921 gcaacttgat ccgatctacg ttgatgtgac ccagtccagc aacgacttcc tgcgcctgaa
    37981 acaggaactg gcgaatggca cgctgaaaca agagaacggc aaagccaaag tgtcgctgat
    38041 caccagtgac ggcattaagt tcccgcagga cggtacgctg gaattctctg acgttaccgt
    38101 tgatcagacc actgggtcta tcaccctacg cgctatcttc ccgaacccgg atcacactct
    38161 gctgccgggt atgttcgtgc gcgcacgtct ggaagaaggg cttaatccaa acgctatttt
    38221 agtcccgcaa cagggcgtaa cccgtacgcc gcgtggtgat gccaccgtac tggtagttgg
    38281 cgcggatgac aaagtggaaa cccgtccgat cgttgcaagc caggctattg gcgataagtg
    38341 gctggtgaca gaaggtctga aagcaggcga tcgcgtagta ataagtgggc tgcagaaagt
    38401 gcgtcctggt gtccaggtaa aagcacaaga agttaccgct gataataacc agcaagccgc
    38461 aagcggtgct cagcctgaac agtccaagtc ttaacttaaa caggagccgt taagacatgc
    38521 ctaatttctt tatcgatcgc ccgatttttg cgtgggtgat cgccattatc atcatgttgg
    38581 caggggggct ggcgatcctc aaactgccgg tggcgcaata tcctacgatt gcaccgccgg
    38641 cagtaacgat ctccgcctcc taccccggcg ctgatgcgaa aacagtgcag gacacggtga
    38701 cacaggttat cgaacagaat atgaacggta tcgataacct gatgtacatg tcctctaaca
    38761 gtgactccac gggtaccgtg cagatcaccc tgacctttga gtctggtact gatgcggaca
    38821 tcgcgcaggt tcaggtgcag aacaaactgc agctggcgat gccgttgctg ccgcaagaag
    38881 ttcagcagca aggggtgagc gttgagaaat catccagcag cttcctgatg gttgtcggcg
    38941 ttatcaacac cgatggcacc atgacgcagg aggatatctc tgactacgta gcggcgaata
    39001 tgaaagatgc catcagccgt acgtcgggcg tgggtgatgt tcagttgttc ggttcacagt
    39061 acgcgatgcg tatctggatg aacccgaatg agctgaacaa attccagcta acgccggttg
    39121 atgtcattac cgccatcaaa gcgcagaacg cccaggttgc ggcgggtcag ctcggtggta
    39181 cgccgccggt gaaaggccaa cagcttaacg cctctattat tgctcagacg cgtctgacct
    39241 ctactgaaga gttcggcaaa atcctgctga aagtgaatca agatggttcc cgcgtactgc
    39301 tgcgtgatgt ggcgaagatt gagctgggtg gtgagaacta cgacatcatc gcagagttta
    39361 acggccaacc ggcttccggt ctggggatca agctggcgac cggtgcaaac gcgctggata
    39421 ccgctgcggc aatccgtgct gaactggcga agatggaacc gttcttcccg tcgggtctga
    39481 aaattgttta cccgtacgac accacgccgt tcgtgaaaat ctctattcac gaagtggtta
    39541 aaacgctggt cgaagcgatc atcctcgtgt tcctggttat gtatctgttc ctgcagaact
    39601 tccgcgcgac gttgattccg accattgccg taccggtggt attgctcggg acctttgccg
    39661 tccttgccgc ctttggcttc tcgataaaca cgctaacaat gttcgggatg gtgctcgcta
    39721 tcggcttgtt ggtggatgac gctatcgttg tggtagaaaa cgtggagcgt gttatggcgg
    39781 aagaaggttt gccgccaaaa gaagctaccc gtaagtcgat ggggcagatt cagggcgctc
    39841 tggtcggtat cgcgatggta ctgtcggcgg tattcgtacc gatggccttc tttggcggtt
    39901 ctactggtgc tatctatcgt cagttctcta ttaccattgt ttcagcaatg gcgctgtcgg
    39961 tactggtagc gttgatcctg actccggctc tttgtgccac catgctgaaa ccgattgcca
    40021 aaggcgatca cggggaaggt aaaaaaggct tcttcggctg gtttaaccgc atgttcgaga
    40081 agagcacgca ccactacacc gacagcgtag gcggtattct gcgcagtacg gggcgttacc
    40141 tggtgctgta tctgatcatc gtggtcggca tggcctatct gttcgtgcgt ctgccaagct
    40201 ccttcttgcc agatgaggac cagggcgtat ttatgaccat ggttcagctg ccagcaggtg
    40261 caacgcagga acgtacgcag aaagtgctca atgaggtaac gcattactat ctgaccaaag
    40321 aaaagaacaa cgttgagtcg gtgttcgccg ttaacggctt cggctttgcg ggacgtggtc
    40381 agaataccgg tattgcgttc gtttccttga aggactgggc cgatcgtccg ggcgaagaaa
    40441 acaaagttga agcgattacc atgcgtgcaa cacgcgcttt ctcgcaaatc aaagatgcga
    40501 tggttttcgc ctttaacctg cccgcaatcg tggaactggg tactgcaacc ggctttgact
    40561 ttgagctgat tgaccaggct ggccttggtc acgaaaaact gactcaggcg cgtaaccagc
    40621 tgcttgcaga agcagcgaag caccctgata tgctgaccag cgtacgtcca aacggtctgg
    40681 aagatacccc gcagtttaag attgatatcg accaggaaaa agcgcaggcg ctgggtgttt
    40741 ctatcaacga cattaacacc actctgggcg ctgcatgggg cggtagctat gtgaacgact
    40801 ttatcgaccg cggtcgtgtg aagaaagttt acgtcatgtc agaagcgaaa taccgtatgc
    40861 tgccggatga tatcggcgac tggtatgttc gtgctgctga tggtcagatg gtgccgttct
    40921 cggcattctc ctcttctcgt tgggagtacg gttcgccgcg tctggaacgt tacaatggcc
    40981 tgccatccat ggaaatctta ggccaggcgg caccgggtaa aagtaccggt gaagcaatgg
    41041 agctaatgga acaactggcg agcaaactgc ctaccggtgt tggctatgac tggacgggga
    41101 tgtcctatca ggaacgcctc tccggcaacc aggcaccttc actgtacgcg atttcgttga
    41161 ttgtcgtatt cctgtgtctg gcggcgctgt acgagagctg gtcgattccg ttctccgtta
    41221 tgctggtcgt tccgctgggg gttatcggtg cgttgctggc tgccaccttc cgtggcctga
    41281 ccaatgacgt ttacttccag gtaggcctgc tcacaaccat tgggttgtcg gcgaagaacg
    41341 cgatacttat cgtcgaattc gccaaagact tgatggataa agaaggtaaa ggtctgattg
    41401 aagcgacgct tgatgcagtg cggatgcgtt tacgtccgat cctgatgacc tcgctggcgt
    41461 ttatcctcgg cgttatgccg ctggttatca gtactggtgc tggttccggc gcgcagaacg
    41521 cagtaggtac cggtgtaatg ggcgggatgg tgaccgcaac ggtactggca atcttcttcg
    41581 ttccggtatt ctttgttgtg gttcgccgcc gctttagccg caagaatgaa gatatcgagc
    41641 acagccatac tgtcgatcat cattgataca acgtgtaatc actaaggccg cgcaagcggc
    41701 cttttttatg cataacctac gaacattaag gagtaattga accaccaact caggatctca
    41761 tacgaaaacc agtattaacc acggataaaa ttcataaaaa atactgattg ttagttaatt
    41821 tatattaagt agcgctaata gatttaataa tccataatca tttagaggct attcttaatt
    41881 atttgcggta attctttatt cattcctcgg ttattacgtc atattcagag caatcctggt
    41941 attagtgtca ccaatttcat ctggcgataa tcctgaaatg ttatgaacag ttcgagcaaa
    42001 ctgcttttac ctgctgcggg ttagtgctag tatgaaaaag tgagtcctgt cccgattcct
    42061 tcctaattgt aatttttcgt aataatgcga tgaaaacctg caaagagtgg cttatagtta
    42121 agctaacaaa cgagagggca agtccaggtc agtaagtttt ttccatcccg aaaggtgtcc
    42181 gttagttcaa ccactaagaa ggggacgcgt tatggatgaa tactcaccca aaagacatga
    42241 tatcgcacag cttaagtttc tctgtgaaac cctgtatcat gactgtcttg caaaccttga
    42301 agaaagcaat catggctggg ttaacgaccc aacctcggcg atcaacctcc agttgaatga
    42361 actgattgag catattgcga ccttcgcact taattacaaa attaagtata atgaagacaa
    42421 taagctcatt gagcagatcg acgaatatct ggatgacacc tttatgttgt tcagcagtta
    42481 tggtattaat atgcaggatc ttcagaaatg gcggaagtca ggtaatcgac tattccgttg
    42541 ttttgtcaat gcgacgaaag agaatcctgc gagtttatct tgttagaatt attacaacca
    42601 tgggtagaag tatgtccgaa aaacctttaa cgaaaaccga ttatttaatg cgtttacgtc
    42661 gttgccagac aattgacacg ctggagcgtg ttatcgagaa aaataaatac gaattatcag
    42721 ataatgaact ggcggtattt tactcagccg cagatcaccg cctcgccgaa ttgaccatga
    42781 ataaactata cgacaagatc ccttcctcag tatggaaatt tattcgctaa taaataattc
    42841 gctttcggag ctataaccgg ctgtttatta agaattttat actttttcac catgaagaca
    42901 taccctatgt gatctttatc acacagatgt aatgggaacg ttctcttcac tgacttttcg
    42961 tcttactgtg ttgccgcatt ttcagcaacc ggaggtcagt aatgagcaca gaaaaagaaa
    43021 agatgattgc tggtgagttg tatcgctcgg cagatgagac gttatctcgc gatcgcctgc
    43081 gcgctcgtca gcttattcac cgatacaatc attccctggc ggaagagcac acattacgcc
    43141 agcaaattct cgctgatcta ttcggtcagg tgacagaggc ttatattgag ccaacgtttc
    43201 gctgtgacta tggctataac atttttctcg gtaataattt tttcgccaac ttcgattgcg
    43261 tgatgcttga tgtctgccct attcgcatcg gtgataactg tatgttggca ccaggcgttc
    43321 atatctacac ggcaacacat cccatcgacc tgtagcacgt aatagcggtg ctgaactggg
    43381 gaaacccgtc accatcggta ataacgtctg gattggcgga cgcgcggtca ttaaccctgg
    43441 tgtgaccatt ggtgataacg tcgtggtagc ctcaggtgca gttgtcacaa aagatgtccc
    43501 ggacaacgtt gtcgtgggcg gtaatccagc cagaataatt aaaaaattgt aatcggtttt
    43561 tcgcaactgt tatgcaaaat tgtggtaaat ctgttacttc ccctctacta ttcccacgtt
    43621 aaaatagggt gttccctgga aagttgcaga taccacgaag gcaaacgatg accgaaatac
    43681 aacgcctgct gaccgaaacg attgagtctc tgaatacccg cgaaaaacgc gacaacaaac
    43741 cccgctttag tatcagtttt atccgtaaac atccggggct gtttatcggt atgtacgttg
    43801 ctttttttgc caccctggcg gtgatgttgc agtccgaaac gctgtcaggc tctgtctggc
    43861 tactggttgt attatttatc ctgcttaatg gtttcttctt tttcgatgtc tacccacgct
    43921 accgctatga agatatcgac gtgctggatt tccgcgtttg ctataacggc gaatggtaca
    43981 acacgcgctt tgtacctgcc gcgctggttg aagccatctt gaactctccg cgtgtcgcgg
    44041 atgttcataa ggaacaactg caaaaaatga tcgtccgtaa aggtgaactg tctttttacg
    44101 atatttttac cctcgctcgc gccgaatcaa catcttaagt tagggttaca taccaggcgt
    44161 aaagctctgc gcctggtcaa atgacaatga tcgtttccac ccatcacttc atgaaatacc
    44221 agctctacct ccttatctcc tgccagcctt tttccacaat cagatatact ttccctacac
    44281 tgtgttaata aggatatgct ggtgagaaca cgacatctgg tcggccttat ttcgggagta
    44341 ctgattcttt cagtattgct gcctgtcggc ttaagcatct ggctggccca tcagcaggta
    44401 gaaacatcgt ttattgaaga gctggatacc tattcctccc gcgtcgctat tcgggccaat
    44461 aaggtggcga cacaagggaa agatgcgctg caagagctgg aaagatggca aggcgctgcc
    44521 tgtagcgaag cccatctcat ggaaatgcgt cgggtatctt acagttatcg ctatattcag
    44581 gaagtggttt atatcgataa caacgttccc cagtgttcgt ctctggagca tgaaagtccg
    44641 cccgatacct tccccgagcc aggtaaaatt tcgaaagatg gttatcgtgt ctggttaaca
    44701 tcgcataacg atttaggcat tatccgttac atggtcgcca tgggaacggc acattatgtc
    44761 gtcatgatcg accccgcttc ctttattgat gtcattccct atagctcatg gcaaattgat
    44821 gccgccatta ttggcaatgc ccataacgtt gtcataacca gcagcgatga aattgctcag
    44881 ggaattatta ccaggctaca aaaaacaccc ggtgagcata tcgaaaataa tggaatcatt
    44941 tacgatatcc tgcccttccc ggagatgaat atttcgatca tcacctgggc ttcaacgaaa
    45001 atgttgcaga aaggctggca tcggcaagtc tttatttggt taccgctcgg gttggtgatt
    45061 ggcctgctgg cagcgatgtt tgtgctgcgt attttgcgcc gtatccagtc accgcatcat
    45121 cggctgcagg atgctatcga aaatcgtgat atttgcgtgc actatcagcc gattgtctcc
    45181 ttagccaatg gcaaaattgt cggtgctgag gcactggcgc gctggccgca gacagacggt
    45241 agttggttgt caccagatag ttttattccg ctggcacagc aaacgggcct ttctgagcca
    45301 ttgacgctac tgattataag aagcgtcttt gaagatatgg gcgactggct gcgtcagcat
    45361 ccacagcagc atatttcgat caatcttgaa tccaccgtgc tcacctcgga aaaaatcccg
    45421 caattgctgc gtgaaatgat caatcactat caggttaatc ccagacagat cgcgcttgaa
    45481 ctcactgaac gcgagtttgc cgatccgaaa accagcgccc cgataatttc tcgctaccgg
    45541 gaggcgggcc atgaaattta tcttgatgat tttggtacgg gatattcaag tttaagttat
    45601 ttacaggatc tggatgtcga cattctgaag atcgataaat ctttcgttga tgcgctggaa
    45661 tataaaaatg tcacgccgca tatcatcgaa atggcaaaaa cactgaaact gaaaatggta
    45721 gcggagggaa tcgaaaccag taaacaagaa gagtggctac gccagcatgg cgtgcactac
    45781 ggtcagggct ggctctacag caaggcatta ccgaaagaag atttcttacg ctgggccgag
    45841 caacatttgt gaatttttgg gctgacggca cgccgcacag cccgtcacgc tacctattcg
    45901 tcgatgattg actcgaatcc gccatagatc attcgcttgc cgtcaaacgg catggactcg
    45961 ccgaactctt tcatccgtgg gtccgacatc atcttttgag tagcagcgtc gcggacctct
    46021 tttgaagggt attcaatcca gctaaagaca acctcttcat tctcttccgc tttcaccgcc
    46081 atacgaaaat cggtcacttt gccatccggt acatcgctgg cccagcattc gacaatacga
    46141 agcgcgccaa actctttaaa caatggcgca gccttagcgg ccatttcccg ataggcatcc
    46201 tttttatcgg caggaacggc aaccacaaaa ccatcaacat acttcatcag acatacctcc
    46261 gaagcgtact gcgcagccag acaattcttg cgacgtcagt tgtggttaaa gtttagccat
    46321 gttggggttt tttgacgaaa cggtgggagg cagaaatggg tgggggccct gccagctaca
    46381 tcccggcaca cgcgtcatct gccttggctg cttccttccg gacctgacct ggtaaacaga
    46441 gtagcgttgc gggagaacca acagagcccc cattgagagc gttgagaacc aacgcgcagg
    46501 cgcattatca ctgctgcccc ggctaattgc aacccatcgc gtgccagatg ctggtttctt
    46561 gcgcaatgcg acttcactcg ggcgtttttc cagattatgc tgaaaaatta cctcaggaag
    46621 aaaagatgga aaaagaagat tcatttcccc aacgcgtctg gcaaatcgtc gccgctattc
    46681 ccgaaggcta tgtcaccact tacggtgatg tggcgaaact ggcgggatcg ccccgcgccg
    46741 cgcgccaggt gggcggtgtg ttaaagcgtc tccctgaagg cagcacctta ccctggcacc
    46801 gggtggttaa tcgccacggc acaatttcgc taaccggacc ggatttacag cgtcagcgac
    46861 aggcattact ggcagaaggt gtgatggtat cgggaagcgg gcaaatcgac ttgcagcgtt
    46921 atcgctggaa ctactaaccc tctccgggcg gagagggtta acgtcgctta atattgcgta
    46981 ggagctggaa ctgccgaaga cggattcacc tgagttggtg aagtcgaagg tacggtagtc
    47041 gttgcaccac cgctggcctg aaccggcacg gcggtttgct gcaccggcac caatgtcagg
    47101 tcggctttag ttccgccctt gttgatcacc ggctgaacgg tatcggtaat aaataccagt
    47161 ttgtcattca cggtaatcgc cgcactcaac agaatacgcg cgttcggctg aacatctgcc
    47221 gggttaaatg gcagaacaaa gctgaatggt gactgtttac cttcagtacg caccgctttc
    47281 tgcgccagca cttttgacgg tgcatcggct aacgacgcgt cagaaagtgt cacggtcagc
    47341 acagcatcag gcggcagtgc gactttctga cggatccaga cggtaccgga gacattcggt
    47401 tgctggatag caggttgttg tgttgctgaa atagacgtat ttgcagccgg ggctggcgtc
    47461 tgaatatccg cgcttttatc tgcgcaagcc gccaacgcaa tcgcaaccgc taaaccactg
    47521 gccatgtgca cgagtttcat tcatttctcc ttattatcaa tgcaccagcg ggctaacttt
    47581 cctcgccgga agagtggtta acaaaatagt aacgtcaaca agtgtggcac acatcacgca
    47641 tttctgcctg taattagccc gtaattcaga ccattgcacc catcggacca gtagcaaatt
    47701 tgcgttatac tcaactcact ttggcttgct gcggcagctt tgttactgga gagttatatg
    47761 agtcaggcgc taaaaaattt actgacattg ttaaatctgg aaaaaattga ggaaggactc
    47821 tttcgcggcc agagtgaaga tttaggttta cgccaggtgt ttggcggcca ggtcgtgggt
    47881 caggccttgt atgctgcaaa agagaccgtc cctgaagagc ggctggtaca ttcgtttcac
    47941 agctactttc ttcgccctgg cgatagtaag aagccgatta tttatgatgt cgaaacgctg
    48001 cgtgacggta acagcttcag cgcccgccgg gttgctgcta ttcaaaacgg caaaccgatt
    48061 ttttatatga cggcctcttt ccaggcacca gaagcgggtt tcgaacatca aaaaacaatg
    48121 ccgtccgcgc cagcgcctga tggcctgcct tcggaaacgc aaatcgccca atcgctggcg
    48181 cacctgctgc cgccagtgct taaagataaa ttcatctgcg atcgtccgct ggaagtccgt
    48241 ccggtggagt ttcataaccc actgaaaggt cacgtcgcag aaccacatcg tcaggtgtgg
    48301 atccgcgcaa atggtagcgt gccggatgac ctgcgcgttc atcagtatct gctcggttac
    48361 gcttctgatc ttaacttcct gccggtagct ctacagccgc acggcatcgg ttttctcgaa
    48421 ccggggattc agattgccac cattgaccat tccatgtggt tccatcgccc gtttaatttg
    48481 aatgaatggc tgctgtatag cgtggagagc acctcggcgt ccagcgcacg cggctttgtg
    48541 cgcggtgagt tttataccca ggacggcgtg ctggttgcct cgaccgttca ggaaggggtg
    48601 atgcgtaatc acaattaaaa aaatagccgg aggtaaaacc gtccggctat tttttgcagt
    48661 gcttgttacg cgttataggc attctcgccg tgactgttga catccagccc ttctcgctcc
    48721 tgctcttccg gtacacgcag accaaccgtc agatccgcca gtttgtagcc aataaatgcc
    48781 accacaccgg accagacgat cgtaatggcg atgctttcca gctgtaccag caactgatgg
    48841 cccatcgtca caccttcagc gaagcccacg ccacccagcg aactggcggc aaaaatccca
    48901 gtcatgatac agccgacaat gccacaaacg ccgtgcacac cgaagacatc gcagggatca
    48961 tccacccgca gcaagcgttt gagcatagta acgccccaca agcccgccag accagctacc
    49021 acgccgataa tcaacgcgcc gccaacccca atgtagccac acgctggcgt cacgccgacc
    49081 agaccggcaa tcgcgccaga acacgctccc agcagagaag gcttaccacg cagcgcccat
    49141 tcaccgaaga tccagccaag aattgccgcc gccgttgcga ccacagtatt cacaaatgcc
    49201 agtgccgcga tttcattcgc cgtgcccgct gacccggcgt taaagccaaa ccaaccaata
    49261 tagagaatgg cagtaccggt gaagaccatt ggcaggttgt gcggtttaaa cgcctctttg
    49321 ccgaagccca cgcgtttgcc tatcagatac gcgcccacca gaccggcgat tgcggcgtta
    49381 atatgcacca ccgtgccacc cgcgaaatcc agcgcaccgt gagaagccag caaaccaccg
    49441 ccccacacca tatgcgcaat cggaatgtaa gagagcgtca gccataccac cacgaaaatc
    49501 aacacagctg agaagcggat tcgttccgcc agcgccccaa cgatcaagcc gacggtaatg
    49561 caggcaaacg agccctgaaa cgccacgtgg atatactgat aaatgctgcc catcaccgcc
    49621 gtcagttcga tgttttttag catcaaccag ttaatgttgc cgaagaagtt gttgccctca
    49681 ccaaacgcca gcgagtaacc gtaaaccacc cagagaatac agaccagtgc aaacgtcacc
    49741 gtcacctgcg tcagcatcga cagcacgttt ttgccgcgaa tcaacccacc gtaaaacagg
    49801 gcaatccccg gaatagtcat aaacagcacc agcgcagtac aaatcatcat aaacgcattg
    49861 tcggctttat cggccaccgc aggtgcagcc attaccagtc ccggcagcat cgccagtgaa
    49921 gcaagcccag tttttatcgt cgctatcttc atttttcgtt cctgttgctg tgtgccagag
    49981 attacagcgc cgcttcgtcg gcttcgccgg tacgaatacg aatgacgcgt tgcaattcag
    50041 cgacgaagat tttgccgtcg ccaatttttc cggtgtaagc cgccttactg acgatatcga
    50101 tcacttcatc gagttggtca tcagcaatcg ccacatcaat ttttactttt ggcaggaagt
    50161 tgacgctgta ttccgccccc cggtacagct cggcatgccc tttctgacgc ccgaaacctt
    50221 tcacttcggt gacggtcagg ccctgaatac caatggaaga taacgcttca cgaacgtctt
    50281 ccagcttgaa tggtttgatt atcacggtca ccagcttcat agatcccctc cggtcagaat
    50341 tcggtaatgg ttctgctaca cgaagaaggt attgcaagcg gtgtgccaga aatgaaaaac
    50401 gagaaagaga gcaggaagtt aagaagattg aaaatgaaaa cgcactatga cagtgcacag
    50461 tgcgttacat ttttgcacca acgatgaaat attgcgctat tcaggcgctc aatgattctt
    50521 cttcacgcac gctggctgcc agctcttcgc ccgcaagttg cagttgatac atctgccagt
    50581 agcgtccctg ggccgccagc agttgctggt gagtgccctg ctccacggct tgcccacgat
    50641 gaagcaccag aatggtgtcg gcatcaacaa tggtcgataa gcggtgagca atcaccacca
    50701 gcgtggtatg ttcacgcaca gccgccagag catgttgaat cgcctgttca gtaccggagt
    50761 caatgctggc ggttgcctca tcaaggatca ggatttgcgg cgtctccacc aacacgcgtg
    50821 ccagtgccag cagttgcttt tgcccgacgg agagattatt cccctgctcg cccagcggcg
    50881 tataaatacc atcactcatg ctgcgcgcca gctccgccag ttgcacggtt tccagcgcct
    50941 gccagacgcg ttcttcggag atatcacgcc ccagcgtcac gttggcgagg aaggtatccg
    51001 ccagcaccac cggatcttgc tgcaccattg ccacgccctg gcgcagcgcg ctgtgactta
    51061 gcgaacttaa tggacgacca tcaaggcgaa tctcaccttc cgttagcggg taatagccca
    51121 tcaataaact ggcgagggtg cttttgccac tgccggtatg cccgaccagt gccacaaagt
    51181 tacgcgaagg cacagagaga ttaatgttct ttagcaccag attgtcatcg cgataagcaa
    51241 atgacacgtt atcgacttcg atggtgccac tctgtaacgg gcgatcatca ttgccatatt
    51301 gctggcgcgg tccgtccatc agttcaaaca cgcgctcacc agcaacaaca gcctgttgca
    51361 gcatcgcctg ttgcgtggtc agttcgatta atggttcgtt aagtcgccca agatagctga
    51421 taaacgcata cagcacgccc acttcaatgg tgccgctagc ggagaagcca aacagcatca
    51481 acaagccaca aagaatgagc gatgaaaaca gactcagcag cggacgcagc agaaaaccgt
    51541 cgaggcgcag ggtttgcatc ctggccatat agtgtgaacg actggcctcc cccatacgtt
    51601 cgccaaatcg cgcctgctga cggaactgct ggataacgct catgccattg atgatttcgt
    51661 taaagccgtc gttgatatcc gctagatagg cgcgcacacg acggacaatc ggcgtgctgt
    51721 aacgctggta tatcaccatt accaccagca ccaccgggaa aatcattatc gccaccagcg
    51781 ccattcgcca gtcgaggctg aacatcgcca ccagcatcgc gcccaccagt gcggcgctac
    51841 gcaggacagt tgccactacg gtaacgtaga gatcgcggat cacttcagtg tcattagtga
    51901 cgcgggaaat cacctgcccg acgggttggg tatcaaactc gcttaatggc tggcgcaatg
    51961 cggcatccat cacgtcggta cgcaactgtt gcactacgcc tactgccgcc cgattaaaca
    52021 gcagcgactg cgcgtaatgt agcccggcgg caaacagttg tagcccaaca tacgccgcag
    52081 ccagccctgc aaccattttc aacggcaggt tatttttcgc taccatattg tcgataaaat
    52141 agctgataag cagcggccca ctgacttctg ccgctgccgc aacccacatc atcaggaccg
    52201 caatccccag cggtttacgc cacggcgaac cgtacgctaa cagacgcttg agagtcggcc
    52261 acagttggct aaaactacgc atcgacggcc tcctcgcgaa tttccggagc gtcgtcgagc
    52321 gccgcctcca gttgttgata gcgatacata tcgcgatacc agtcgctttg ttgcgccagc
    52381 tcatcatgat tgccacgctg ggcgatatgt ccgtgctgca tcacaataat ttcactggct
    52441 tccgtcagtg ccgaaaggcg atgggcactg atgattaccg ttcttccctg tccccactga
    52501 cgcaggttat gcaggatctg gtgctctgtg cgtccgtcca ccgccgaaag cgcatcatca
    52561 aggatgagga tttccgcgtt gactaataac gctcgagcaa tggagatacg ctgtttttgc
    52621 ccaccggaaa gcatcacgcc gcgctcgccc acttctgtat cgtaaccttg cggtagacgc
    52681 aaaatatcgt catgtacgct ggctaaccgc gcgacatgct caatctcttg ctgggtggca
    52741 ttcgggcaac ccaacgcgat gttgttcgct acggtgtcgg aaaaaaggaa cggtgtctgg
    52801 ctaactaccg ccaggcggct acgccagcta tcgagttgta acttcgtcag aggaatatca
    52861 tgaaagcgaa tatccccctc gctgacgtcg aaatgacgct gaatgagcga caacagggta
    52921 cttttgccgg aaccagtcgg cccgcagata cccagcatct gaccgggttt cagggcgaaa
    52981 ttgacgtttt ccagcgcagg atggtcagtc tgcggatacg tgaactggtg aatatttaca
    53041 tcaagttcgc cacgcccttc cggcacgggt tcgctaccat cgttcaccac cggcgcttcc
    53101 gccagcatcg cacgaatacg gctgtacgca gcactaccac gttccacaat gttaaacatc
    53161 catgccagcg ccagcattgg ccaaatcatc agacctaaat acatcataaa actggtgagc
    53221 tggcccagcg ttaaactgcc ctgcgccacc atccaactac cgccgccaat cgccagcaag
    53281 ttcgccatac caatcgcgat atagatggtt gggtcgaaac gagcatcaat acgcgccacc
    53341 cgcatgtttt ttttgccggt atcttcggca tccgcggcaa ataacgccga ctggcgatct
    53401 tccagaccaa aggctttgat catgcggata ctggtgaggc tttcctgggt gcggtcatta
    53461 agactagaaa acgccgcctg tgccagctta aagcgttcat gcaaggcatc gccgttgcgc
    53521 ttgatcatga tcgccatcac tggcatcggc aacagggcaa ataaggtcaa ctgccagcta
    53581 atttgcgtag acatcataat caacacagcg cagcccatca ccagtgaatc caccagcgtc
    53641 agcacccctt ctccggcggc aaacacgacg cgatcgacgt cattggtcgc acgagccatg
    53701 agatcacccg tgcgatgacg caggtaaaac tcaggatgct gccggcttag ctgacggtaa
    53761 taatcttcac gcagttcaac agccagttga taagacgcac caaacagcaa tacccgccag
    53821 acgtaacgca ggagataaac cacaacggca atcagcacca tggtggcgat ccacatcagg
    53881 atctgcccgg tagtaaagtg ttgttctgtc acgccatcga caacaatacc aaccactttt
    53941 ggcggaacca gttgcagcat cgcgataatg acaagcaagg cgacagcccc gagatagcga
    54001 cgccattccc gacggaaata ccagcttaat tgagcaaata atcgcacgcg ttgtgtcctg
    54061 acctgattct ggatatttat tcgatgggta aagaagtggt gtatttaatc tgttccatcg
    54121 cgaagctgga agtgacgtcc gacagccccg gcacgctgtt taccagacgc ttataaaact
    54181 cgtcgtagcg tttcatgtcg gcaacctgga cgcgcatcag ataatcgtat tcaccagcca
    54241 tgcgccagaa ccccagcact tctggcattt cggtaaccac cgtgacaaag cggcaatacc
    54301 attcgctgct gtgatgttgc gtttttatca gcacaaaggc ggtcaggccg aggcctattt
    54361 tttccggatc cagcagggcg actttgccga taaggatacc gtcgtcctcc agccgtttca
    54421 ggcgcttcca gcaaggggtg gttgtcagat taacggcttc agccagtgcc tgcaaagaga
    54481 gggtgcaatc ctgctgcagt aaggccagca gcttacggtc aattttatct aacatagccc
    54541 ttccacggag aatttttttc tcttttaatt ctattttaaa ggtgaaatcg cgacaattta
    54601 ttctgtgcgg tttaaacacc acggcacaaa atgacaaatt caacgcaaaa aaaaaccggg
    54661 caattgcccg gtgctggaag ggatctcgtt attcggggga ataaggtaga tgtggatagt
    54721 ccagccagtg cgtcaaatag tgagagacag cctgatttcg gcaatgtcca atcaccggta
    54781 aatgcgggag ctccgcgcgc agttgcggca tcgcattgcc cataataaac ccgctaccga
    54841 cgctgcctaa catttcgcga tcgttcatcg catcaccaaa ggccatgcaa tcgcgcaacg
    54901 ataaacctaa atgttgggtc agcaccgtca atgcagcgcc tttattgcag cccaccggca
    54961 gcacttcgag gcaatccgtg gcggaaaaac acaaatgtgc acgctcgcct aatgcttcgt
    55021 atagctggat ctgcaagcgt gtaagatcgt cgtgatcgcc acagaagcag atcttggtga
    55081 cgctgccgag tggcattttt ttgacatcga ttatctgata acgaaaaccg ctatagacaa
    55141 atgcctgcaa caacgcaggg atctctttcc cggtaaacca accgtcgtca ttgaagatat
    55201 gcatgctggc tcgggtatcc cattgctgat acagcaccag ctccgcgaca tccgcaggta
    55261 aatcatcacg atgtaaaagt tcaccttcca gagaatgcac gcgcgttccg ttgccggtaa
    55321 tcaaatatgc atccagcgat agcgccccga gaatatgctg catctccagc gcatgacgcc
    55381 ccgtggcaaa agtgagggta atgtcgcgtt cacgcagtcg cgccaaagta gagagggttt
    55441 tctcacctaa atgatggtca ggcatcaata aagtgccatc catatcaaat gctgccagac
    55501 gagccatttc tttctccact ctgtgacacg gttaatggtg attgagtatc acctgatata
    55561 tacggaagta atagtgaata gttaaataat attgttccgg gtttatatgc gattgctcaa
    55621 ccgtcttaac cagtatcaac gtctgtggca accttcagcc ggaaagccgc aaaccgtcac
    55681 cgtcagcgaa ctggccgaac gctgtttttg cagcgaacgc catgttcgta cgctgttgcg
    55741 tcaggcacag gaggcgggat ggctggagtg gcaggcgcag tcaggacgcg gaaagcgcgg
    55801 acaattacgc tttctggtca cgccggaatc gctacgcaat gcgatgatgg aacaggcact
    55861 ggaaaccgga aagcagcaag atgtgctgga gctggcgcaa ctggccccag gtgagctgcg
    55921 cactctgtta cagccgttta tgggcggaca atggcaaaac gatacaccca cgttgcgtat
    55981 tccctactat cgcccgctcg aaccgctaca accaggcttt ttgcccggcc gtgccgagca
    56041 gcatctcgcc gggcagatat tttccggcct gacccgcttc gataataata ctcagcgccc
    56101 gattggcgat ttagcgcatc actgggaaac ctctactgac gggttacgct gggactttta
    56161 tcttcgttca accctacact ggcataacgg cgatgcagta aaagcctcac acttacacca
    56221 gcgattattg atgctgttac aactgccagc actggatcaa ttatttatta gcgtgaagcg
    56281 tattgaagtc acccatccgc agtgtctgac cttcttttta catcgccccg attactggct
    56341 tgcgcaccgg ctggcgagct attgcagcca tctggcgcat ccgcaattcc cactgatcgg
    56401 cactggtcct tttcgcttaa cacaattcac agcggagctg gtgcgcctgg agagccatga
    56461 ttattaccat ttgcgtcatc cgctgcttaa agcggttgag tactggataa ctccgccgct
    56521 tttcgaaaaa gatttgggaa ccagttgtcg gcatcccgtg caaatcacca tcggcaaacc
    56581 ggaggagctg caacgggtca gccaggtcag tagtggcatc agtttaggtt tttgctattt
    56641 aacgttgcgc aaaagtcccc gactctccct ctggcaggcg cgaaaagtga tctccattat
    56701 tcatcaatcc ggtttattac aaacgttaga agtcggagaa aacctgatca ccgccagtca
    56761 tgcattactg ccaggctgga ctattccgca ctggcaagta ccggatgaag tcaaactacc
    56821 gaaaaccttg acgctggttt atcacctacc gatagaactt cataccatgg cagaacgcct
    56881 acaggcgaca ctggcagcgg aaggctgtga actcacaatt atttttcata acgcaaaaaa
    56941 ctgggacgac acgaccctac tggcacacgc agacctcatg atgggcgaca gattaattgg
    57001 cgaagcaccg gaatatactc tggagcaatg gctacgttgc gatccactat ggccacatgt
    57061 tttcgacgct ccagcatatg cacatctgca atcgacgctg gacgcggtgc aagtaatgcc
    57121 tgatgaggaa aaccgattta atgccctgaa agcggttttt agccagttaa tggcagacgc
    57181 gacgctgacg ccgctgttca actatcacta tcgcattagt gcccctcccg gcgtgaacgg
    57241 tgtgcgactg acaccgcgcg gctggtttga atttaccgaa gcctggcttc ccgcgccgtc
    57301 gcaatgaata gctggtccgg gttaatcgca ggcgttacca taacgctttt attgttcaag
    57361 caggattatc tatgaaacgt gctgtcgttg tgttcagtgg aggccaggat tccaccacct
    57421 gtctggtgca ggcattacaa caatatgatg aagtccattg cgtgacgttc gattacggtc
    57481 agcgacatcg cgcagaaatc gacgtggcac gcgaactggc gctgaaactg ggagcacgcg
    57541 cgcataaggt tcttgatgta acgctgctca acgagctggc ggtcagcagc ctgacacgtg
    57601 acagcattcc ggtgcctgat tatgaacctg aagccgatgg catcccgaat acgtttgtcc
    57661 ctgggcgtaa tattttgttc ctgacgctgg cggcaatata tgcgtatcag gtaaaagcag
    57721 aagccgtaat taccggcgtc tgtgaaacgg atttctccgg ctacccggat tgccgcgatg
    57781 agtttgtgaa agcactaaac catgccgtca gtttgggcat ggcgaaagat attcgttttg
    57841 aaacgccgct gatgtggatt gataaagcgg aaacctgggc gctggcagat tattacggca
    57901 aactggattt agtccgtaac gaaacgttga cctgctataa cggcattaaa ggcgacggtt
    57961 gcggtcattg tgcggcatgt aatttacgcg ccaacggttt gaatcattat ctggccgata
    58021 aaccgacggt gatggcagcg atgaagcaga aaaccgggtt gaggtaatta ttccgggtgt
    58081 cgccggatgc ggcttgagca tccggcacca caaaacgttt acttaaccat ctgctccagc
    58141 ttttcgcgca attccccttc cagagctaat gctttctgcg ttttaagatc aatacaaaca
    58201 aacgtaataa gcgcatccgc taccacctgc ccttccggct ccagtgtaat gacctggctt
    58261 aagatgccgc ttttaccgtt taattgctgc aactgactgg taatagttaa caggtcactt
    58321 aataccgctg ggcgacgata gttaatattg atattgacca cgacgaaggc gatgttatgg
    58381 gccgtcatcc actgaaaact gtcgctattt tccaacccat cccagcgggc ttcttcgaga
    58441 aattcaaggt agcgggcgtt gttgacgtgc tggtaaacgt cgagatgata tccacgaact
    58501 ttgatttgtg tttgcatagc gcaataacct tacgttgttg ttataagtac agaggtcata
    58561 actggtatga cctcttcagt ctggcaaaaa attgccacta tgcaaattaa ttacagggtt
    58621 aataccgcca gattacgttc caccagcgaa ttgcccatcc ccggcacctg ctttagatcc
    58681 tccaccgttt taaacggacc gtactcttcg cgataactga caatcgcctg cgctttcttc
    58741 aggccaacgc cattcatcgc gcgggctagc tcttccgcgc tggcattatt aatgctgacc
    58801 cgggtgcctt cttcgtcact ggctttcgcc ggtactgctg ctttactttg tgctgcagga
    58861 gcttccgctt tggtttctac cgttgtcggt ttcgccacag aagctgccgc cagcgcgcta
    58921 tgagacattc cggcacaggc cagggacagg gtaatgagca gtgctttaat tccgtgtttc
    58981 atactgtttt ctccttgttt gttaacagtg gaatcacctt aacggcagtg aaaacagtaa
    59041 acaaatggca atgttcagaa atggaaaagg ccgcgaaagc gaccttttct tgttacagct
    59101 gcaacgcatt tttttgcgag gcggcttcag gattattgct gttccagcgc atcgccaatt
    59161 ttgattttcg cctctttacg caggttactc atcagagctt caaagacgat ttgtgcgttg
    59221 ttctgggtga taccctgcac catcgctttt ttctgatctt ccggcattga accttgtttc
    59281 acttcatcca gcgccagcag aaccacatta ccttgcatat cggtcgccat accgtagctc
    59341 ggtttgtctt tcgctggcag tggcagtgca aacgccgcct ggctaatcgg gtcacgaccg
    59401 gaacggctta agattttcgg ctcgccaaat ttcagaccgg cagcctgcat agcttccgca
    59461 cctttgccgg ctttcaaatc aaccagcagt ttctcagcat ccactttcgc ctgttgttca
    59521 gctttgttgt gctgaaccag tgccttaact tgttcctgaa catctgccaa cggtttcacc
    59581 gcttccggtt tgtgctcgct gatgcgcagc acgaatgcgc ggtcgccgtc tacggtgatg
    59641 atgtcagagt tgatgcccgg cgcgccgttt tcacctacca gaccgccgtt aaagatagcg
    59701 tcggcaaccg gcttgaagtt caactcttcc ggcaggttat ctttgctaaa ccaacccgtc
    59761 tgagtggctt taacgccggc agcttgctct gcaccggcca gagactcggt gtcgttgctt
    59821 gccgcatcgc tcactttctg ctgcagcgca tagtacgcat cgagggcttt ttcgtgtttc
    59881 actttcgccg caatgtcgtc acgtacttcg tctaacgatt tcactttcgc tggctgaatg
    59941 tcgtccagac gtacaatcag gaaaccgacc gaagatttga tgacaccaga cagttgccct
    60001 ttttctttca gaccagcatt tttcagttcg tcggggatag tggcatcttc taaccaaccc
    60061 atatcgccgc cgttacgggc agagataata tcggcagatt tttctttggc taatgcagca
    60121 aaatcaccgc cttcattcag ctcatcaagt accgctttcg cttcatcttc agttttggtc
    60181 tggatgatgc tgtagcgggt acgctgcggc tgggtgaatt gatcctgatg ctgatcgtag
    60241 tagctctgga tatccgcatc gctaaccggt tgctgcatcg ttgcggcatc cagcttgatg
    60301 taactcacgc ggaattgttc cggcgtcatg aaattgtttt tgttttgttc gtagtagctg
    60361 gcaatctcct gttcggtcac aggctgcttc gccgccagcg cgttaacatc gatagtcgcc
    60421 tcacgcacca cgcgttgttg cgcgaccagt gccgccagct cgtcggtttc acctttcagc
    60481 ataaaatcgg taccggcaac accgttaatc agctgttggg tagtgagctg gttacgcagc
    60541 gcctgggcgt actgatcggc ggtcatcccc atctggttga ggataccgtt atagcggctg
    60601 ttatcaaatt tgccgtcaac ctggaaggct ggggtcgcga aaatcgcctg tttaacctgc
    60661 tcatcactga tacccagttt cagctcacga gcgtactgat ccaacagcgc ctcgtcgatc
    60721 agacgattca gcacctgttg acgcagggtt ttcatatagc cttcgttcgc tgccagctcg
    60781 gagtattgat cgcccagctg ttgctgcatg cgattacgct cgctgttaaa ggcgttctcg
    60841 aactgcccac ggctgatttc ctggtcattc acttttgcgg cgtagttatt gcctccgcca
    60901 atcaggtaac cactcacgcc ggtcaatatg aacgacacga taatgatacc gaaaataatc
    60961 ttgagcacga gactgtttgc agccgtgcgt aagctgtcca tcatggtgta acaacactcc
    61021 gctgtagatg actgtgtacc tcacgcaacg tatcgatgcg cgcaaaggcc tattgtgaca
    61081 agaaacgggg gcaattgtca gcccacaaga cgcagaaagt caccgaatac aaataaaaaa
    61141 ggcacatcag tagatgcgcc cttgaacttc gtcacatccc caccggggac aacgcttagt
    61201 ttaccgcgtc tttcagtgct ttacctgcac ggaagctcgg tactttagca gcagcgatgg
    61261 tgatctcttt accggtctgc gggttgcggc cagtacgggc agcacgctct ttaacggcaa
    61321 aagtaccaaa acctaccagt gctacatcat ccccttcttt cagagattca gttacggaag
    61381 caataatagc atctaacgca cggccagccg cagctttaga gatatcagcc cctgcagcaa
    61441 tcttgtcgat caattgagat ttattcactc ttctcttcct ctttataatt tatatcgcac
    61501 ttgaatcctt caaggtacga acgcgcagca gttatatcag gccagccatc cccttacaac
    61561 accccttaat aagggcaagc ccgatccgcc atctaactta gcgagacaaa aaaaggctgg
    61621 caagcccgaa ttagcctgcc agccctgttt ttattagtgc attttgcgcg aggtcactat
    61681 tttgcagtca caacctgcat accagacggt tcattttgta gcgccagagt cagaacttcc
    61741 tcaatgcgct tcacaggatg aatgtccaga tcggcaatta cgttgtcagg aatctcttcc
    61801 agatcgcgtt tattttcgaa cggaattagc actgttttaa tcccgccgcg atgcgctgcc
    61861 aggagttttt ctttcaaacc accgatcggc agtacctgac cacgcagagt gatctcaccg
    61921 gtcattgcca catcggcacg aaccgggtta ccggtcaggc aagaaaccag cgcggtgcac
    61981 atagcaatac cggcactcgg accatctttc ggcgtcgcac cttccggaac gtggacgtgg
    62041 atgtcacgtt tttcgtaaaa atcagggttg atccccagtt tttccgcacg cgcacgaacc
    62101 accgttaacg ccgcctgaat agactcctgc atcacttcgc cgagcgaacc ggtataggtc
    62161 agtttgcctt tacccggaac acatgcggtt tcaatggtca gcaagtcacc gcccacttcc
    62221 gtccacgcca gaccggttac ctgaccgaca cggttttcgt tatcagcgcg accatagtcg
    62281 aaacgctgaa caccgaggta gtcatgcagg ttatcgccgt taatttcgat atgttttaat
    62341 gacttatcga gcagtaactg cttaaccgct ttgcggcaca gtttggagat ttcacgctcc
    62401 agaccacgca cgcccgcctc acgggtgtag taacgaataa tgccgataat ggcgctatcg
    62461 tcgacggtca gctcaccttt tttcagtgca ttacgttcaa tctgcttcgg cagcaggtga
    62521 cgtttggcga tgttcagttt ttcatcttcg gtataaccgg agaggcgaat cacttccata
    62581 cgatccagca gcggtgccgg aatgttcatg gagttcgacg tcgcgacaaa catcacgtcg
    62641 ctgagatcgt aatccacttc caggtagtgg tcgctgaacg ctacgttctg ctctggatcc
    62701 agcacttcaa gcagtgcaga ggccggatcg cctcgcatgt cagaagacat tttgtcgatc
    62761 tcatcgagca ggaacagcgg gtttttcacg cccactttcg ccattttctg gatcagttta
    62821 cccggcatag aaccgatgta agtacggcgg tgaccacgga tttccgcttc atcacgcacg
    62881 ccgcccagcg ccatacggac atatttacgc ccggtggctt tggcaatgga ctgaccaaga
    62941 gaggttttac ctacccccgg cggccctacc aggcagagga tcggtccctt gattttgttg
    63001 acacggcttt gaaccgcaag gtactcaagg atgcgatctt tcacgcgctc cagaccataa
    63061 tggtcggtat caaggatttc ctgcgcctga cgcaggtctt ttttgacctt gctgcgcgca
    63121 ttccacggta cctgtaccat ccagtcgata taaccacgca ctacggtcgc ttctgccgac
    63181 atcggagaca tcattttcag cttctgcaac tctgcttccg ctttctcttt tgcctctttc
    63241 ggcatcttcg ccgcgtcgat tttgcgcttc agggcttcgt tttcgtccgg cgcgtcgtcc
    63301 atttcaccga gttctttctg aatagctttc atttgctcgt tcagatagta ctcacgctgg
    63361 gatttctcca tctgcttttt aacgcggttg cgaatgcgtt tctcaacctg cagcagatcg
    63421 atttccgatt ccatcattgc catcagatat tccagacgtt cgttaacgtc ggacatctcc
    63481 agaacggact gtttgtcagc cagtttcagc ggcatatgtg cagcaatggt atccgccaga
    63541 cgcgccggat cgtcgatgct attcagcgac gtcagcactt ctggtgggat ttttttgttc
    63601 agcttgatgt agccttcgaa ctggctgatt gcagtacgca ccagcacttc ctgttcccgc
    63661 tcatcaatgg tcggcgactc cagatactcc gccttcgcag aaaagtgttc gccattgtca
    63721 gagagcgcag aaatacgcgc gcgctgtaac ccctcgacca gcactttgac ggtgccgtca
    63781 ggcagtttca gcatctgcaa tatagaggcc acggtcccga cggtgaaaag atcgtttaca
    63841 cccggctcat ccgttgaagc ttctttctgc gcgaccagca taattttttt atcatggtcc
    63901 atcgccgctt ccagacaacg gatagatttt tcccgcccga caaataaggg gatgaccatg
    63961 tgcggataaa ccaccacatc gcgcagcggc aatacgggga tttcaatgcg ttcagaacgc
    64021 tcaggattca tagagctctc tcttagttta atttccgcca ggtaatcaga tgacacgact
    64081 gtgcttcacg ccatctatta acatgtacgt cagtatatgg ggatgtttcc cccacattca
    64141 acgccgagaa tagaggaaaa attaaagggg agataaaatc cccccttttt ggttaactaa
    64201 ttgtatggga atggttaatt attcaccaga tgcctgttgc gcttccggct tgccataaat
    64261 cagcaacggt ttgctttgac catcaattac cgactcgtcg ataaccactt tttcgacatc
    64321 ttccatggac ggcagatcgt acatggtatc gagcagtgcg gcttctacga tggaacgcag
    64381 gccacgggca ccggttttac gcgccatcgc tttcttagcg atagcatcca gcgcctcgtc
    64441 acggaattcc agatccacgc cttccagatt aaacagcgcc tgatactgct tggtcagggc
    64501 gtttttcggc tctttgagga tctgaatcag agcttcttcg ctcagttcat tcaacgttgc
    64561 gacaaccggc agacgaccaa tgaactcagg gatcagacca aacttgatca gatcttccgg
    64621 ttcaacctgc gccagcagct cgccttcgct tgctttgtcg gacttcgctt ttaccgtcgc
    64681 gccaaaacca atgccggagc cggtttctac acgatgggaa atcactttat ccagaccggc
    64741 aaacgcaccg ccacaaataa acaggatctt agaggtatca acctgcaaga attcctgctg
    64801 cggatgttta cgcccacctt gcggtggaac agcagctacc gtaccttcga tcagtttcaa
    64861 cagtgcctgc tgtacgcctt caccggaaac gtcacgggta atagacgggt tgtctgactt
    64921 acgagaaatc ttgtcgattt catcgatgta gacaatcccg cgctgcgctt tctgtacgtc
    64981 gtaatcgcac ttttgcaaca gcttctgaat gatgttttca acgtcttcgc ccacataacc
    65041 ggcttcggtc agcgtggttg cgtcggccat ggtgaacggg acgtccagca ggcgcgccag
    65101 cgtttcagcc agcagcgttt taccggaacc ggtcggaccg atcagcagaa tgttactttt
    65161 gcccaactcg acaccattgc tggtatcgcc gttgcgcaga cgtttgtaat ggttgtatac
    65221 cgcgaccgcc agcacttttt tcgcctgttc ctggccgata acgtaatcgt ccaggtggtt
    65281 gcgaatttca tgcggcgtcg gtagcgcact gcgttcacga tgcggtgcaa cttctttaat
    65341 ctcttcgcga atgatgtcgt tacataaatc aacacattcg tcgcagatat acacggatgg
    65401 accggcaatc agcttgcgca cttcatgctg gcttttgccg caaaaagagc aatacagcaa
    65461 tttgcctgag ccatctttgc gtttatctgt catgggtcaa aacctcttct ttgttctttg
    65521 tgccgcacac gacgacgcaa atgccattct caggcgcaag ccgcttacag cgttgtgccg
    65581 ccctggataa gtatagcggc acagttgcgc ctctggcatc aattacgatg ggtcagaatc
    65641 gaatcgacca gaccgtattc caccgcttca ggggcggaaa ggaagcgatc gcgctcggta
    65701 tcacgttcaa tctgttctaa tgattgaccc gtatgaagcg ccataagttc attcatgcgc
    65761 cctttaactt tcagaatttc acgggcatga atttcgatat cggtcgcctg gccctggtag
    65821 ccgcccaacg gttggtgaat catcacgcgc gaattcggca ggcaaaaacg tttacctttt
    65881 gcccctgcgg tcagcaagaa agcgcccatc gaggccgcct ggcccataca gatggtgctg
    65941 acatcaggct tgataaactg catggtgtca tagatagaca tcccggcagt gatcaccccg
    66001 cctggggagt taatgtacag atagatatct ttttctgggt tttccgcttc caggaacagc
    66061 atctgcgcca caatcaggtt agccatgtgg tcttcaacct ggccagtcag aaaaatgacg
    66121 cgttccttaa gtagacgaga atagatatca aaagagcgct caccgcgtga ggtctgttca
    66181 atgaccatcg gcaccagcgc catatggggt gcaaagttat ctcgttcgcc gctgtatgac
    66241 atttccgtct cctggataaa attgaaaaaa cctgctgtac cgattgtaac cttatggacg
    66301 gattatcagc tagtccctgt gttatgggta cggcatcacc atatttcaag cataacaatc
    66361 ttttgttgtt acgctaacac cgaaagaggc ttttcgcacg gttccatgca aaattcatga
    66421 caaaaaaaag cccaccacct ggcggtgacg ggcctttgtg cgaatttagc gcgttatgct
    66481 gcgtaaatta cgcctgctgg ttcatcagct cgttgaaagt ggtttctttt tcagtcactt
    66541 tcgctttcgc cagtacagct tcaacagcct gttcttccag agcaacattg cgcatgttgt
    66601 ccatcagttc tttgtttttg ctgtagaact cgataacttc tttcggatct tcgtacgcag
    66661 aagccatctc ttcgatcagg cctttcacgc gctcttcgtc agctttcagc tcgttggtgc
    66721 ggataacttc gcccagcagc aggccaacaa ctacgcggcg tttagcctgt tcttcgaaca
    66781 gttcgcgcgg cagttccaga gcttgttttt cgttgccacc gaaacgctgt gcagcctggc
    66841 gacgcagaac gtcgatttcg ctgtcgatca gcgcagccgg tacgtcgatg tcgttagctt
    66901 ttaccagacc ttcgatcgcc tgagacttaa cgcggttacg gatggcgctc ttcagctcgc
    66961 gctccatgtt tttacgcact tcagcgcgca gaccttctac ggaaccatct tcaacgccga
    67021 aacgtttgat gaattctgca gtcagttccg gcagttcacg ctcttcaact ttcttcaggt
    67081 tgatagcgaa tttcgctgct ttacctttca ggttttctgc gtggtattct tccgggaagg
    67141 tcacgtcgat ggtgaactct tcgccagctt tgtggccttt gataccgtct tcaaagcccg
    67201 ggatcatacg accctggccc atcgccagta cgaaatcaga cgctttaccg ccttcgaact
    67261 cttcgccgtc tacagaaccg gtgaagtcga tggttacgcg gtcttctgct tcaacagcgc
    67321 cgtctttttc tttccaggtc gcctgctgtt tacgcagagt atccagcatg ccgtcaacgt
    67381 cagcgtcggt cacttcaacg atcggttttt caacttcgat cgcttccaga ccctgcagtt
    67441 caacttccgg ataaacttca aactctacag agtaagtgaa gtcttcaccc agcttgtatt
    67501 cgcccggaac ataagtcggt gcgccagccg gattgatttt ttctttaatg atggcgtcaa
    67561 tgaagttacg gctcatcagg tcacccagaa cgtcctggcg tacagacgcg ccataacgct
    67621 gagcaacgat attcattggc actttgcctt tgcggaagcc gtcaatacgt acttttttcg
    67681 caacgttgac cagctcgctt ttaacagcgg tctcgatgct gtcagcagcg atagtaatcg
    67741 ttacacggcg gccaaggcct tgagtggttt caactgaaac ttgcatcttg ttacctcaaa
    67801 aaatcacagt gctcggtcaa ctcttacccc gcaagcacag gttgttggct tcgcggaacc
    67861 gggatgttct tataatcaat cacattccct gttaccagaa tcatcccgaa agcattcaaa
    67921 taggacgcgg cattatagcg gcatcacttt tatgagtcga gaacggttat tgcgcgctgt
    67981 cgcgtatttt ttcacaattc ccgggcaatt ttcgtctgaa tgctgggcaa aaagcgcaaa
    68041 attcagacaa aacaaaacgg cccgtaggcc gtttttcata aaatctttag caacatactg
    68101 gaaaagcgcc gacagttgca aatgcgtttt tacgcgatgc ttcctgctcc acgacaggga
    68161 ggagaggcaa agacggtgtc ctgcaaccct tcccactcct taatagtgta agtatgcaga
    68221 gccagcgcat gaacggtagt agagagttcc tccgctaaag tactgtaaat cattcgatga
    68281 cgattcagaa aacgttcacc cgtaaaacga tcgctgacca gcacaacttt aaaatggctt
    68341 tcagagccgg ctgggacatt gtgacgatag ctttcatcca ctacttcgag gaatacgggt
    68401 tggaacgccg cccttaattt ttcttctatc cgctcacgta tcatcatgaa atatctcctc
    68461 cgacaacgct gagatgtcat ccatcccttt aaatactagc cgcttttacc gtttccattg
    68521 cagcttaaca acaaatattt aggtttcgtc ctggtttttc cgtcaagcgt atgaagttta
    68581 ctgatttaaa gattgaaaca caggcctcgc atcagtgttt cttttgccag gggcgattat
    68641 ttcgtcaaca tgatgaattt acatgcctta cccacttccc ctcgccgttg gcaatgttat
    68701 gatggcggga atttttacca aacacgctta agagtctctg agagcccgaa catgttcaaa
    68761 aaaatcctct tcccgttagt tgctctgttt atgcttgcag gatgcgcaaa accgccaaca
    68821 actattgaag tttccccgac gattacactg ccacagcagg atccaagcct gatgggcgtc
    68881 accgtaagca ttaatggtgc cgatcagcgt accgatcagg cgctggcaaa agtcacccgc
    68941 gataatcaaa tcgttaccct gaccgcctcc cgcgatctgc gtttcctgct gcaagaagtg
    69001 ctggaaaaac agatgaccgc gcgtggttac atggttggtc cgaatggccc ggttaatctg
    69061 caaatcatcg ttagccaact gtatgctgac gtgtcccagg gcaacgtgcg ctataacatc
    69121 gctaccaaag cggatatcgc catcatcgct accgcgcaga atggcaacaa aatgaccaaa
    69181 aactatcgtg ccagctacaa cgttgaaggt gcgttccagg cctccaacaa aaatatcgcc
    69241 gatgcggtta acagtgtgct gaccgatacc atcgctgata tgtctcagga caccagcatt
    69301 cacgaattta tcaagcagaa cgcgcgttaa tttctgccct ctggcccggt gcaaaccggg
    69361 cctgtagacg cccatgtcca gtcaatattt acgtattttt caacagccgc gttcagccat
    69421 attgctgatc ctgggttttg cttccgggct accgctcgcc ctgacatccg gtaccttaca
    69481 ggcctggatg acggtcgaga atattgatct caaaaccatt ggtttcttct ctctggtagg
    69541 ccaggcttac gtttttaaat tcctctggtc accgctgatg gaccgctaca cgcccccatt
    69601 ttttgggcgg cggcgcggtt ggctgctcgc cacgcaaatc ctgttattag tcgccattgc
    69661 ggcgatgggt tttctcgaac ctggcaccca actccgctgg atggcggcac tggcggtggt
    69721 gatcgctttt tgctcggcct cccaggatat tgtcttcgat gcgtggaaaa ccgatgtgct
    69781 cccggcagaa gaacgtggtg cgggcgcggc aatcagcgtg ctgggttacc gtttagggat
    69841 gctggtttcc ggcggcttag ccctgtggct ggcagataaa tggctgggct ggcagggcat
    69901 gtactggttg atggcggcgc tgttgctccc ttgtattatc gcgacgttgc ttgcaccaga
    69961 accgaccgac accattcctg tgccaaaaac gctggaacaa gcggttgttg cacctctgcg
    70021 agatttcttt ggtcgcaata atgcctggct tattttgctt cttatcgtgc tgtataagct
    70081 gggcgacgca ttcgccatga gcctgacaac cacgtttttg attcgcggcg tcgggtttga
    70141 tgcgggtgaa gtaggcgtgg ttaacaaaac gcttggctta ctggcgacca ttgtgggcgc
    70201 attgtacggt gggattttga tgcagcgcct gtcgctgttc cgggcgctgc tgattttcgg
    70261 cattttacaa ggtgcgtcta acgctggtta ctggctgctg tcgattactg ataagcatct
    70321 ctacagcatg ggcgcagccg tctttttcga aaacctctgt ggcgggatgg gcacatcagc
    70381 ctttgtcgcg ctgttaatga cgctgtgtaa taagtcattt tccgcaactc aatttgccct
    70441 gctctcagcg ctttccgctg taggacgagt ttatgtcggc cccgtggcgg gttggtttgt
    70501 tgaagcacac ggctggtcga cattctatct attctccgtc gccgctgccg taccggggct
    70561 tattttgctg ctggtttgcc gccagacgct tgaatataca cgagtaaatg acaactttat
    70621 ctcccgtacc gaatatccgg caggttatgc ctttgccatg tggacactgg cggcgggcgt
    70681 cagcctgttg gccgtgtggt tactgctgtt gacgatggac gcgctggatt tgacgcactt
    70741 ctctttcctg cctgctctgc tggaagtcgg ggttttagtc gccctttctg gcgtcgtgct
    70801 tggtggtttg ctggattatc tggcgctacg aaaaacgcat ctgacgtaat ctgtaaatat
    70861 tatttagctg tagtaatcac tcgccgtaat tattacggct aaataaacat cagtatcgct
    70921 taataatatt tgttcttttg tgcggcttag cgtttggaaa ttattgacgc aatttatgaa
    70981 ttctattttt tcttacacga ttcagctaat gagtctttat tttcccccca cccaattgtc
    71041 accataatga taattatttg ttaaacaatt gttttattcc agattggtta taccaattgc
    71101 ccgtccaaac tccttctgca ctcccctttc gttataacgc ccttttgcaa cagcttctta
    71161 aaatcaactt gatatgtttt gcaacatatg tgacctgaca gccaaatcca agtaacagga
    71221 atttaatcat gtttacagta atgtaacctt cccgtaaaat gcccacacac tttaaacgcc
    71281 accagatccc gtggaattga ggtcgttaaa tgagactcag gaaatacaat aaaagtttgg
    71341 gatggttgtc attatttgca ggcactgtat tgctcagtgg ctgtaattct gcgctgttag
    71401 atcccaaagg acagattggt ctggagcaac gttcactgat actgacggca tttggcctga
    71461 tgttgattgt cgttattccc gcaatcttga tggctgttgg tttcgcctgg aagtatcgtg
    71521 cgagcaataa agatgctaag tacagcccga actggtcaca ctccaataaa gtggaagctg
    71581 tggtctggac ggtacctatc ttaatcatca tcttccttgc ggtactgacc tggaaaacca
    71641 ctcacgctct tgagcctagc aagccgctgg cacacgacga gaagcccatt accatcgaag
    71701 tggtttccat ggactggaaa tggttcttca tctacccgga acagggcatt gctaccgtga
    71761 atgaaatcgc tttcccggcg aacactccgg tgtacttcaa agtgacctcc aactccgtga
    71821 tgaactcctt cttcattccg cgtctgggta gccagattta tgccatggcc ggtatgcaga
    71881 ctcgcctgca tctgatcgcc aacgaacccg gtacttatga cggtatctcc gccagctaca
    71941 gcgggccggg cttctcaggc atgaagttca aagctattgc aacaccggat cgcgccgaat
    72001 tcgaccaatg ggtcgcaaaa gcgaaacagt cgccgaacac catgtctgac atggctgcgt
    72061 tcgaaaaact ggccgcgcct agcgaataca accaggtgga atatttctcc aacgtgaaac
    72121 cagacttgtt tgccgatgtg attaacaagt ttatggctca cggtaagagc atggacatga
    72181 cccagccaga aggtgagcac agtgcacacg aaggtatgga aggcatggac atgagccacg
    72241 cggaatccgc ccattaaagg ggttgaggaa gaataaagat gttcggaaaa ttatcacttg
    72301 atgcagtccc gttccatgaa cctatcgtca tggttacgat cgctggcatt attttgggag
    72361 gtctggcgct cgttggcctg atcacttact tcggtaagtg gacctacctg tggaaagagt
    72421 ggctgacctc cgtcgaccat aaacgcctcg gtatcatgta tatcatcgtg gcgattgtga
    72481 tgttgctgcg tggttttgct gacgccatta tgatgcgtag ccagcaggct cttgcctcgg
    72541 cgggcgaagc gggcttcctg ccacctcacc actacgatca gatcttcacc gcgcacggcg
    72601 tgattatgat cttcttcgtg gcgatgcctt tcgttatcgg tctgatgaac ctggtggttc
    72661 cgctgcagat cggcgcgcgt gacgttgcgt tcccgttcct caacaactta agcttctggt
    72721 ttactgttgt tggtgtgatt ctggttaacg tttctctcgg cgtgggcgaa tttgcgcaga
    72781 ccggctggct ggcctatcca ccgctatcgg gaatagagta cagtccggga gtcggtgtcg
    72841 attactggat atggagtctc cagctatccg gtataggtac gacgcttacc ggtatcaact
    72901 tcttcgttac cattctgaag atgcgcgcac cgggcatgac catgttcaag atgccagtat
    72961 ttacctgggc atcactgtgc gcgaacgtac tgattattgc ttccttccca attctgacgg
    73021 ttaccgtcgc gttgttgacc ctggatcgct atctgggcac ccatttcttt accaacgata
    73081 tgggtggcaa catgatgatg tacatcaacc tgatttgggc ctggggccac ccggaagttt
    73141 acatcctgat cctgcctgtt ttcggtgtgt tctccgaaat tgcggcaacc ttctcgcgta
    73201 aacgtctgtt tggttatacc tcgctggtat gggcaaccgt ctgtatcacc gtgctgtcgt
    73261 tcatcgtttg gctgcaccac ttctttacga tgggtgcggg cgcgaacgta aacgccttct
    73321 ttggtatcac cacaatgatt atcgccatcc cgaccggggt gaagatcttc aactggctgt
    73381 tcaccatgta tcagggccgc atcgtgttcc attctgcgat gctgtggacc atcggtttta
    73441 tcgtcacttt ctcggtgggc gggatgactg gcgtgctgct ggcagtaccg ggcgcggact
    73501 tcgttctgca taacagcctg ttcctgattg cgcacttcca taacgtgatc atcggcggcg
    73561 tggtcttcgg ctgcttcgca gggatgacct actggtggcc taaagccttc ggtttcaaac
    73621 tgaatgaaac ctggggtaaa cgcgcgttct ggttctggat catcggcttc ttcgttgcct
    73681 ttatgccgct gtatgcgctg ggcttcatgg gcatgacccg tcgtttgagc cagcagattg
    73741 acccgcagtt ccacaccatg ctgatgattg cagctagcgg tgcagtactg attgcgctgg
    73801 gtattctctg cctcgttatt cagatgtacg tttctattcg cgaccgcgac cagaaccgtg
    73861 acctgactgg cgacccgtgg ggtggccgta cgctggagtg ggcaacctct tccccgcctc
    73921 cgttctataa ctttgccgtt gtgccgcacg ttcacgagcg tgatgcattc tgggaaatga
    73981 aagagaaagg cgaagcgtat aaaaagcctg accactatga agaaattcat atgccgaaaa
    74041 acagcggtgc aggtatcgtc attgcagctt tctccaccat cttcggtttc gccatgatct
    74101 ggcatatctg gtggctggcg attgttggct tcgcaggcat gatcatcacc tggatcgtga
    74161 aaagcttcga cgaggacgtg gattactacg tgccggtggc agaaatcgaa aaactggaaa
    74221 accagcattt cgatgagatt actaaggcag ggctgaaaaa tggcaactga tactttgacg
    74281 cacgcgactg cccacgcgca cgaacacggg caccacgatg caggcggaac caaaatcttc
    74341 ggattttgga tctacctgat gagcgactgc attctgttct caatcttgtt tgctacctat
    74401 gccgttctgg tgaacggcac cgcaggcggc ccgacaggta aggacatttt cgaactgccg
    74461 ttcgttctgg ttgaaacttt cttgctgttg ttcagctcca tcacctacgg catggcggct
    74521 atcgccatgt acaaaaacaa caaaagccag gttatctcct ggctggcgtt gacctggttg
    74581 tttggtgccg gatttatcgg gatggaaatc tacgaattcc atcacctgat tgttaacggc
    74641 atgggtccgg atcgcagcgg cttcctgtca gcgttctttg cgctggtcgg cacgcacggt
    74701 ctgcacgtca cttccggtct tatctggatg gcggtgctga tggtacaaat cgctcgtcgc
    74761 ggcctgacca gcactaaccg tacccgcatc atgtgcctga gcctgttctg gcacttcctg
    74821 gatgtggttt ggatctgtgt gttcactgtt gtttatctga tgggggcgat gtaatgagtc
    74881 attctaccga tcacagcggc gcgtcccatg gcagcgtaaa aacctacatg acaggcttta
    74941 tcctgtcgat cattctgacg gtgattccgt tctggatggt gatgacaggg gctgcctctc
    75001 cggccgtaat tctgggaaca atcctggcaa tggcagtagt acaggttctg gtgcatctgg
    75061 tgtgcttcct gcacatgaat accaaatcag atgaaggctg gaacatgacg gcgtttgtct
    75121 tcaccgtgct aatcatcgct atcctggttg taggctccat ctggattatg tggaacctca
    75181 actacaacat gatgatgcac taagagcggc ggttatgatg tttaagcaat acctgcaagt
    75241 aacgaaacca ggcatcatct ttggcaacct gatctcggtg attgggggat tcctgctggc
    75301 ctcaaagggc agcattgatt atcccctgtt tatctacacg ctggttgggg tgtcactggt
    75361 tgtggcgtcg ggttgtgtgt ttaacaacta catcgacagg gatatcgaca gaaagatgga
    75421 aaggacgaag aatcgggtgc tggttaaagg cctgatctct cctgctgtct cgctggtgta
    75481 cgccaccttg ctgggtattg ctggctttat gctgctgtgg tttggcgcga atccgctggc
    75541 ctgctggctg ggggtgatgg gctttgtggt ttatgtcggc gtctatagcc tgtacatgaa
    75601 acgccactca gtctacggca cattgattgg ttcgctctcc ggcgctgcgc cgccggtgat
    75661 tggctactgt gcagtaaccg gcgagttcga tagcggcgca gcgatcctgc tggctatctt
    75721 cagcctgtgg cagatgcctc actcctatgc catcgccatt ttccgcttta aggattacca
    75781 ggcggcaaac attccggtat tgccagtggt aaaaggcatt tcggtggcga agaatcacat
    75841 cacgctgtat atcatcgcct ttgccgttgc cacgctgatg ctctctcttg gcggttacgc
    75901 tggatataaa tatctggtgg tcgccgcggc ggttagcgtc tggtggttag gtatggctct
    75961 gcgcggttat aaagttgctg atgacagaat ctgggcgcgc aagctgttcg gcttctctat
    76021 catcgccatc actgccctct cggtgatgat gtccgttgat tttatggtac cggactcgca
    76081 tacgctgctg gctgctgtgt ggtaacaaaa cctctctatt aaaaaggtgc tacggcacct
    76141 tttttattgt ctgagatcag agatacggct aataaccgta tgtcttgaca gagtgagcag
    76201 atgaacataa attaatcata cggttgatag ccgtattatg tatgagatcg actccctacg
    76261 atttcattca gttaatcaaa gaggtcataa tgcctggaaa aacagccact ctacccgatg
    76321 tcgataaaac gctgaaaaat gcgcgggtcg aactcaaaac tagtcccgac gccaaaaaca
    76381 aacttcgtga agctgcgcaa gccgttgggg tagatttaag cgcttttatt ttgagcgctg
    76441 ctatggaacg cgccgaaagt gtgcttgata accaacgtcg ccgtgagctt tcgaatcaaa
    76501 gctgggaact gatgaaccaa ctcatcgctg aacctgctca accgacgctc gccctcaagg
    76561 cgttaatgaa aaggaaaaac agcgatggtc gacaagcatg aagagattac tctgcccata
    76621 gtcctctcct gtaattatca gtctgatatt acttatcctg ggcaaaaaca gtttgattgc
    76681 ggtaaccctg ttatcgataa atttgtacgc gcatcgctaa agaaaagtgt gcgtaatagc
    76741 gactgtgcgg ctaaagcact tattgacaga caaagtggtg aactgatcgg catctgtact
    76801 tttacggcat attcgctgga aaaacaacgc gtttctggcg tccttcaggg ttcacaacct
    76861 tcagaaattg gtgttgtcag attagtcatg ttgggggtag cacggaagta tcaaaagcag
    76921 ggctttggtc aggacctact atgtgatttt tttgaacatg taaaaataat tcaccaggca
    76981 ttaccaatta aaggggttta tcttgatgct gaccctgccg ccattaattt ttatgctcgt
    77041 ctcggctttg ttcagctttc agcgacacca aatgcttttg gtgctgtacc tatgtttttg
    77101 gcgattcagc atattctcgc ggcttagatt attatcgcca cccgccaggg caagttttgc
    77161 ctcagccggg ggctgagcag cgttaccact tttgttcaat tgcccccgct ttcagcaact
    77221 ccacatcctt gccgttaatg gttgccgttg cggcaacgat tgtggtcctt acagttgcac
    77281 aagattttcg ctcaaattcc ggtttataaa gaataagaga cgaattactg gtaaatgaac
    77341 caaataggta atcagtaaag ctaatattca gccggtttaa accgaaaggc gcgaagccaa
    77401 ccgtttggtt aatctcctta ccggatgggc gacgaatgct gaatgtcacg cgaagattgg
    77461 ccacttcgcc taatttattg gtggtggcga agaggctatc catgcaggaa aaacctttat
    77521 ctaaaaaatt atctcgcatc ccagaacggg taaccgtaat cacgggtaac gtatcgtcaa
    77581 ccgtttttct gtcaatcatg tcttttcgac aagtagccag aaagtcttcc gggccaccat
    77641 aaatgtggac acctttatca agatattcct tcgctttctt acaatctacc tcaacatact
    77701 gaccattggc gtacataatg cccaacctgg accatgctaa attcacaccg tgctgcgcgg
    77761 cctgattaaa tagtgcatac gctttggcat aatccacccg cacctgctca ccgtcgtagt
    77821 agataccccc cagcgctaac ggagcttctc tgtcaccttg tttagccgct aactcgaacc
    77881 atttaatcgc ttcctgaaca tcaggtttgg tatcataacg aggctgataa tattcccagc
    77941 ctaacaggct ctgcgcgtcg atatctcccg attcagccat tttatgcagt gtatttataa
    78001 catcgggagc aggtttacca ccgtatatgc tgtcatacaa ttcatgcgct ttctcgctgg
    78061 ccaccacgct tggtgaaact atcagcatta cagaaaataa tattctttta gttaacatgt
    78121 atacctttat gtcctcactg tcatatattt ccataataat taaccaccaa atatccattt
    78181 aatgaataaa tacagtgcca taaaggccca agtaataagc acacatttag cctgaaacat
    78241 tatcatccat gtcaccaaat cgtttattta gtgagataaa actagcatat tcgtaagata
    78301 aaaaatgcac atggcaatca agaaatgata ttattacttt gttgatgtaa aactatttag
    78361 ttttaaaatt cattttttca acatatagag cattcatttt atgaatgcaa aaaaacatac
    78421 ctgacacaca aattactctc ctctgtaata ttttctcatt aacactctgt ttacccaaca
    78481 tgcgctccgc actacactat gtgggcattt ttttaagggg tggtaatgaa cgattataaa
    78541 atgacgccag gtgagaggcg cgcgacctgg ggtttaggga ccgtattctc gttgcgcatg
    78601 ctgggcatgt ttatggttct gccggttctg accacgtacg gcatggctct gcaaggcgcc
    78661 agcgaagcat taatcggtat tgccattggt atttatggtc tgactcaggc cgtttttcag
    78721 attccgtttg gcctgctttc cgaccgcatt ggtcgcaaac cattaattgt cggtgggctg
    78781 gcggtgtttg ccgccggtag cgttatcgct gcgctttccg actccatctg gggaattatt
    78841 ctgggccggg cgctacaagg ctctggagca attgccgccg ccgttatggc gctgctttcc
    78901 gatctcacgc gcgaacaaaa ccgcaccaaa gcgatggcgt ttatcggcgt gagctttggc
    78961 attacctttg ccattgcgat ggtgcttggc ccgatcatca ctcacaaact tgggctgcac
    79021 gcgctgttct ggatgatcgc tattctggca acaaccggca ttgcgttgac catttgggtt
    79081 gtgcccaaca gtagcactca cgtacttaat cgtgagtccg gaatggtgaa aggcagtttc
    79141 agtaaagtgc tggcggaacc gcggctgcta aaactcaact ttggcattat gtgtctgcac
    79201 atgcttctga tgtctacgtt tgttgccctg cccggacagc tagctgatgc ggggttcccg
    79261 gcggctgaac actggaaggt ctatctggcg acgatgttaa tcgcctttgg ctcggtcgtg
    79321 cctttcatta tctacgctga agttaagcgc aaaatgaagc aagtctttgt cttctgcgtc
    79381 gggttgatcg tggttgcgga aattgtgttg tggaacgcac aaacgcagtt ctggcaactg
    79441 gtggtcggcg tgcagctttt ctttgtggcg tttaatttga tggaagccct tctgccctca
    79501 cttatcagta aagagtcgcc agcaggttac aaaggtacgg cgatgggtgt ctactccacc
    79561 agccagtttc ttggcgtggc gattggcggt tcgctgggcg gctggattga cggcatgttt
    79621 gacggtcagg gggtatttct cgctggcgca atgctggccg cagtgtggct ggcagtcgcc
    79681 agtaccatga aagaaccgcc gtatgtcagc agtttgcgca ttgaaatccc ggcggacatt
    79741 gccgcaaacg aagcgttaaa agtgcgtttg ctggaaactg aaggcgtcaa agaagtgttg
    79801 attgcagaag aagagcattc agcttatgtg aaaatcgaca gcaaagtgac aaatcgcttt
    79861 gaggttgaac aggcaattcg tcaggcataa aaaacgcggc gaattgcctg ctgcgctacg
    79921 cttaccaggc ctacaaagtt cttgagttac aaaccgttgt aggccgaatc aggcgttcat
    79981 gccgcatctg acatgaacaa aacgcacatt gtcgcgatta atcgcggaag tttttgaact
    80041 ggaacggctg gccgagatcg ccaccacgta ccatcgccat gacagcctgc aaatcatcac
    80101 gagatttgcc agtcacacgg atctcatcgc cctgaatttg cgcctgcact ttcagtttgc
    80161 tgtctttaat catcttgacg attttcttct gggtcgcgct ctcaatgccc tgtttcagtt
    80221 tcgcttccac aaaccaggtt ttaccgctat gaacgatatt ttccggtaca tccagtgaac
    80281 tgccttcaat gccgcgcttc agcagcttgg cacgcagaat atccagcaac tgattgacct
    80341 ggaagtcgga ctcgctcaac actttgatgg ttttgctggc gtcgttcagc tcaaatgagg
    80401 cttcaacgtt acggaagtca aaacgggact ccacttcgcg actcgcgtta tcgaccgcgt
    80461 tacgtgcttc ctgaagatca acttcagaga caatatcgaa agatggcatc ttttcctctc
    80521 ccttcatttt tgatgcgaag cataatacct gcaaagttaa ataaccaaca gtcctgcacc
    80581 aggacgtatc ccttaattgt gcatagtcgc aacagcatgc acaattaagg gatagcctta
    80641 ttgaacaccc ggagtggttg cgggtgagga ggaacaatga aaattaccgt attgggatgc
    80701 ggtgccttag ggcaattatg gcttacagca ctttgtaaac agggtcacga agttcagggc
    80761 tggctgcgcg taccgcaacc ttattgtagt gtgaatctgg ttgagactga tggttcgata
    80821 tttaacgaat cgctgaccgc caacgatccc gattttcttg ccaccagcga tctgctcctg
    80881 gtgacgctga aagcatggca ggtttacgat gccgtcaaaa gcctcgcgtc cacactgcct
    80941 gtaaccacgc caatactgtt aattcacaac ggcatgggca ccatcgaaga gttgcaaaac
    81001 attcagcagc cattactgat gggcaccacc acccatgccg cccgccgcga cggcaatgtc
    81061 attattcatg tggcaaacgg aatcacgcat attggtccgg cacggcaaca ggatggcgat
    81121 tacagttatc tggcggatat tttgcaaacc gtgttgcctg acgttgcctg gcataacaat
    81181 attcgcgccg agctgtggcg caagctggcc gtcaactgtg tgattaatcc actgaccgcc
    81241 atctggaatt gcccgaatgg tgaattacgt catcatccgc aagaaattat gcagatatgc
    81301 gaagaagtcg cggcagtgat cgagcgcgaa gggcatcata cttcagcaga agatttgcgt
    81361 gattacgtga tgcaggtgat tgatgccaca gcggaaaata tctcgtcgat gttgcaggat
    81421 atccgcgcgc tgcgccacac cgaaatcgac tatatcaatg gttttctctt acgccgcgcc
    81481 cgcgcgcatg ggattgccgt accggaaaac acccgcctgt ttgaaatggt aaaaagaaag
    81541 gagagtgaat atgagcgcat cggcactggt ttgcctcgcc cctggtagtg aagagactga
    81601 agccgtcacc actatcgatc tgctggttcg cggcggtatc aaagtcacca ctgccagcgt
    81661 cgccagcgat ggcaacctgg ccattacctg ctcgcgcggc gtgaagctgc tggcggatgc
    81721 gccgctggtc gaggtggctg atggcgaata tgacgtgatc gtactgcctg gtggcattaa
    81781 aggcgcagag tgttttcgcg atagtaccct gctggttgaa accgttaaac agttccaccg
    81841 ttccgggcgt atcgtcgcgg ctatttgcgc cgcgccagcc accgtgctgg taccgcacga
    81901 tatcttcccg attggcaata tgaccggctt cccgacgctg aaagacaaaa ttcccgccga
    81961 acaatggcag gacaagcgcg tcgtctggga tgcacgggta aaattgctga ccagccaggg
    82021 gccgggtacg gctattgatt ttggtctgaa aattatcgac ctgctggttg ggcgcgagaa
    82081 agcccatgaa gtggcatcac aactggtgat ggcggcaggg atttataatt attacgagta
    82141 gtgtcggatg cggcaaacgt cgcatctgac cagatgcgac gtaaaaacca caaattatgg
    82201 gcgatacacc ttcacattgt taaagccctg ctcgcgcaga tagagcgcct gcagacggct
    82261 catcaccccg cgctcacacc acagtagcca ggttctgttc tggtcgagat cgccaaactt
    82321 ggtgctcagt ttatagaacg gcagagaaac tacatcaatc ccttcgactt tcagtggctt
    82381 atcttcctgt tcatcgatag aacggatatc gaggatcacg tcgttcgggc cgaagccatt
    82441 gacggtttcc acttccacca cttcctgctc ggtctgctgg gcgatttcgc ggatatcaac
    82501 gttattcgct tcttcaacca ctttatcgag aatgctgaag tcgaatttct cttcttccgc
    82561 ttcaatcttc gacttaaccg ctttcaccgt cgggcttttg gagataacac cgcaatattc
    82621 cggcatcgtg cgagcaaagt cttcggtgcc aatctggcga gccaggttga tgatgtgctc
    82681 tttgtcgtaa gaaatcagcg gacgcaggat cagcgtatcg gagacgttat caatcaggcg
    82741 caggttggtc agcgtctgac tggacacctg gccgagcgct tcgccggtga ccagcgcctg
    82801 tacgccgtaa cgttcagcca ctttagacgc ggcacgcacc atcatacgtt tgaggataac
    82861 gcccatctga ccgtcgtcga ttttctcgag aatttccccg acgaccggtt cgaaattaat
    82921 agcgacaaaa cgcacgcggt gggagctgcc aaaacggttc cacagataat gcgccacctg
    82981 acgcacgcca atttcatgcg ccgcgccgcc aaggttaaag aaacagtaat gcacgcggca
    83041 gccgcgacgc atcaacatat aactggaaac accggagtcg aaaccaccgg aaatgagcga
    83101 cagcacatct tcctgggtgc cgatcgggaa accgccaata ccttcgtagc ggcctttaat
    83161 cagcaggaga cgatcgtctt ccacttccag atggacagtc acttccggat tggtcagctt
    83221 cacgcgcgcg gactcaatat gctgatttaa accgccgccg acgtaacgtt ccacatcaat
    83281 cgagctaaaa tcatgtttgc cacgacgctt cacgcgtacg cagaaggttt tgccttccag
    83341 ctgatcgcga tactgaacca acgctttctc aaaaatatcg tgcatgtcgg taaacggcac
    83401 gtcttcgact tcgagaatat ggtggatacc cggaatacgg gtcagggcgt cgcgaatagc
    83461 cagacgctgg ttttcatctt ttgcgcgaac ttcgatgtta tcccagtggc ggacgacagc
    83521 gagcgtctca tcatagtgct ttaaaacgtt acgaatgttc ccggtaagga tttttataaa
    83581 gcgcaagcgc acagattggc ttttgatggt gatttccggg aacaatttaa tgataaactt
    83641 catggcggca atggttcgtt ggcaagcctt aagcgacttg tatagggaaa aatacagcag
    83701 cccacacctg cggctgcatc caggcgcgga agtataccac taacatcgct ttgctgcgca
    83761 catcacctta ccattgcgcg ttatttgcta tttgccctga gtccgttacc atgacggggc
    83821 gaaaaatatt gagagtcaga cattcattat gccgaagaaa aatgaggctc ccgccagctt
    83881 tgaaaaggcg ctgagcgagc tggaacagat tgtaacccgt ctggaaagtg gcgacctgcc
    83941 gctggaagag gcgctgaacg agttcgaacg cggcgtgcag ctggcacgtc aggggcaggc
    84001 caaattacaa caagccgaac agcgcgtaca aattctgctg tctgacaatg aagacgcctc
    84061 tctaacccct tttacaccgg acaatgagta atggactttc cgcagcaact cgaagcctgc
    84121 gttaagcagg ccaaccaagc gctgagccgt tttatcgccc cactgccctt tcagaacact
    84181 cccgtggtcg aaaccatgca gtatggcgca ttattaggtg gtaagcgcct gcgacctttt
    84241 ctggtttatg ccaccggtca tatgtttggc gttagcacaa acacgctgga cgcacccgct
    84301 gccgccgtag agtgtatcca cgcttactca ttaattcatg atgatttacc ggcgatggat
    84361 gatgacgatc tgcgtcgcgg tttgccgacc tgccatgtga agtttggcga agcaaacgcg
    84421 attctcgctg gcgacgcttt acaaacgctg gcgttctcga ttctaagcga tgccaatatg
    84481 ccggaagtgt cggatcgcga cagaatttcg atgatttctg aactggcgag cgccagcggt
    84541 attgccggaa tgtgcggtgg tcaggcatta gatttagacg cggaaggcaa acacgtacct
    84601 ctggacgcgc ttgagcgtat tcatcgtcat aaaaccggcg cattgattcg cgccgccgtt
    84661 cgccttggtg cattaagcgc cggagataaa gggcgtcgtg ctctgccagt actcgacaag
    84721 tacgcagaga gcatcggcct tgccttccag gttcaggatg acatcctgga tgtggtagga
    84781 gatactgcaa cgttgggaaa acgccagggt gccgaccagc aacttggtaa aagtacctac
    84841 cctgcacttc tgggtcttga gcaagcccgg aagaaagccc gggatctgat cgacgatgcc
    84901 cgccagtcgc tgaaacaact ggctgaacaa tcactcgata cctcggcact ggaagcgcta
    84961 gcggactaca tcatccagcg taataaataa acaataagta ttaataggcc cctgatgagt
    85021 tttgatattg ccaaataccc gaccctggca ctggtcgact ccacccagga gttacgactg
    85081 ttgccgaaag agagtttacc gaaactctgc gacgaactgc gccgctattt actcgacagc
    85141 gtgagccgtt ccagcgggca cttcgcctcc gggctgggca cggtcgaact gaccgtggcg
    85201 ctgcactatg tctacaacac cccgtttgac caattgattt gggatgtggg gcatcaggct
    85261 tatccgcata aaattttgac cggacgccgc gacaaaatcg gcaccatccg tcagaaaggc
    85321 ggcctgcacc cgttcccgtg gcgcggcgaa agcgaatatg acgtattaag cgtcggtcat
    85381 tcatcaacct ccatcagtgc cggaattggt attgcggttg ctgccgagaa agaaggcaaa
    85441 aatcgccgca ccgtctgtgt cattggcgat ggcgcgatta ccgctggcat ggcgtttgaa
    85501 gcgatgaatc acgcgggcga tatccgtcct gatatgctgg tggtcctcaa cgacaatgaa
    85561 atgtcgattt ccgaaaatgt cggcgcgctc aataaccatc tggcacagct gctttccggt
    85621 aagctttact cttcgctgcg cgaaggcggg aaaaaagttt tctctggcgt tccgccaatt
    85681 aaagagctgc tcaaacgtac cgaagaacat attaaaggca tggtagtgcc tggcacgttg
    85741 tttgaagagc tgggctttaa ctacatcggc ccggttgacg gtcacgatgt gctggggctt
    85801 atcaccacgc tgaagaacat gcgcgacctg aaaggcccgc agttcctgca tatcatgacc
    85861 aaaaaaggtc gtggttatga accggcagaa aaagacccca tcactttcca cgccgtgcct
    85921 aaatttgatc cctccagcgg ttgtttgccg aaaagtagcg gcggtttgcc gagctattca
    85981 aaaatctttg gcgactggtt gtgcgaaacg gcagcgaaag acaacaagct gatggcgatt
    86041 actccggcga tgcgtgaagg ttccggcatg gtcgagtttt cacgtaaatt cccggatcgt
    86101 tacttcgacg tggcaatcgc cgagcaacac gcggtgacct ttgccgccgg tctggcgatt
    86161 ggtgggtaca aacccattgt cgcgatttac tccactttcc tgcaacgcgc ctatgatcag
    86221 gtgctgcatg acgtggcgat tcaaaagctc ccggtcctgt tcgccatcga ccgcgcgggc
    86281 attgttggtg ctgacggtca aacccatcag ggcgcttttg acctctctta cctgcgctgc
    86341 ataccggaaa tggtcattat gaccccgagc gatgaaaacg aatgtcgcca gatgctctat
    86401 accggctatc actataacga tggcccgtca gcggtgcgct acccgcgtgg caacgcggtc
    86461 ggcgtggaac tgacgccgct ggaaaaacta ccaattggca aaggcattgt gaagcgtcgt
    86521 ggcgagaaac tggcgatcct taactttggt acgctgatgc cagaagcggc gaaagtcgcc
    86581 gaatcgctga acgccacgct ggtcgatatg cgttttgtga aaccgcttga tgaagcgtta
    86641 attctggaaa tggccgccag ccatgaagcg ctggtcaccg tagaagaaaa cgccattatg
    86701 ggcggcgcag gcagcggcgt gaacgaagtg ctaatggccc atcgtaaacc agtacccgtg
    86761 ctgaacattg gcctgcctga cttctttatt ccgcaaggaa ctcaggaaga aatgcgcgcc
    86821 gaactcggcc tcgatgccgc cggtatggaa gccaaaatca aggcctggct ggcataatcc
    86881 ctactccact cctgctatgc ttaacaaatt attcatagac tctaaataat tcgagttgca
    86941 ggaaggcggc aaacgagtga agccccagga gcttacataa gtaagtgact ggggtgaacg
    87001 aatgcagccg cagcacatgc aacttgaagt atgacgagta tggcaggagt ggcagcatgc
    87061 aatacaaccc cttaggaaaa accgaccttc gcgtttcccg actttgcctc ggctgtatga
    87121 cctttggcga gccagatcgt ggtaatcacg catggacact gccggaagag agtagccgtc
    87181 ccatcattaa acgcgcgctg gaaggcggca taaatttctt tgataccgcc aatagctatt
    87241 ccgatggcag cagcgaagag atcgttggtc gcgcactgcg ggatttcgcc cgtcgtgaag
    87301 acgtggtcgt tgcgacgaaa gtgttccatc gcgttggtga tttaccggaa ggattatccc
    87361 gtgcacaaat tttgcgctct atcgacgaca gcctgcgccg tctcggcatg gattatgtcg
    87421 atatcctgca aattcatcgc tgggattaca acacgccgat cgaagagacg ctggaagccc
    87481 tgaacgacgt ggtaaaagcc gggaaagcgc gttatatcgg cgcgtcatcc atgcacgctt
    87541 cgcagtttgc tcaggccctg aagctacaaa aacagcacgg ctgggcgcag tttatcagta
    87601 tgcaggatca ctacaatctg atttatcgcg aagaagagcg cgagatgctg cctctgtgtt
    87661 atcaggaggg cgtggcggtg attccgtgga gcccgctggc gcgggggcga ctgacgcgtc
    87721 cgtggggaga aactaccgca cgactggtgt ctgatgaggt ggggagaaat ctctataaag
    87781 aaagcgatga aaatgacgcg cagatcgcag agcggttaac gggcgtcagt gaagaactcg
    87841 gtgcaacacg agcacaagtt gcgctggcct ggttgttgag taaaccgggc attgccgcac
    87901 cgattatcgg tacatcgcgg gaagaacagc ttgatgagct gctgaacgcg gtggatatca
    87961 ctttgaagcc agaacagatt gccgaactgg aaacgccgta taaaccgcat gcggtcgtag
    88021 gatttaaata agagtccagg cctgatgaga cgtgacaagc gtcacatcag gcatcggtgc
    88081 acaactacga cagaataccc agcggccagt gatgaccgat aaagtacagg atgcctgcgg
    88141 aaatcacccc ggcgacaata tcgtcgatca tgatccccat gccgccatgt acattgcgat
    88201 caaaccagcg gatcggccac ggcttccaca tatccagaat acggaaaatc acaaacccgg
    88261 cggcaaccca ctgccagtca ttggtcggca gcgccatgag cgtgatccac ataccaataa
    88321 attcgtccca gacaatgctg ccgtgatcgt gcacgcccat atctttcgcc gtttgatgac
    88381 aaagatagac gccgatacag atccccaaca tcaccaccag cgagtagagc tgccagggta
    88441 aaaaggtcat cagataccag aacggaatcg ctgccagcga tcccatcgtg ccaggaacga
    88501 ttgggcttaa tccacttccg aatccgacag caagcagatg ccacggatta ctcatcttca
    88561 ggcgactttt cgcgacatct ttatggcgtg gcaaaatggt catatccttt ccagtcaaac
    88621 gtgacaggtt cgccgtcacg aataaaacaa agcccttcga tatcggcggt catttgcccg
    88681 atacaggtaa acggtacgcc caggtgtccg agagccacat ccagcgcgcc acggttcagt
    88741 tccggcacag tgaaacacaa ctcgtaatct tcaccgccag agagcgccca gcgcagcgcc
    88801 tgttccggtt caacatggcg agaaagcgca tcagaaaacg gcagcaatgc caggtcaata
    88861 cgtgcgccgc agtcgctggc tttcacgata tgcccgagat cggaaatcag accgtcagag
    88921 agatcgatag ctgaatttgc cagatcgcgc agtgcctgtc cctgtaaaat acgcggcgat
    88981 ggacggagat gacgtttgat caagtagtcc gcatctttag catcggcaac ctgcaaacgg
    89041 ttttgcaaaa tcgccagccc ggcggcgcta tcgcccggtg taccggtcac atagatccag
    89101 tcacccggtt tcgctccaga gcgcgttaag gctcgtccca tcggaacaaa gccgtggata
    89161 cccaacgtca ttgataatgg cccacgcgtg gtatcgccgc caatgagttg catatcgtaa
    89221 taattgagaa gatcaaacaa actgtcgctg aaggactcaa gccacgcttc gtctacgtcc
    89281 ggtaaggtta atgccagcgt cagccaggcc ggatcggccc ccatcgctgc cagatcgctt
    89341 aggttcaccg ccagtgcttt atacgccaga tcagcaggat cgatatcatg gaggaagtgg
    89401 ttgcccgcca ccagcgtatc agtgctgatc gccagggtct gtttctcggg gatattgaga
    89461 agagcgcaat cgtcgccgat gcccagttcg acatcaagac gagaacttct tacacggtca
    89521 aaataacggg caatcaggga gaactcgcca catgccatac gttatgcctc agcaggtaaa
    89581 aaagaaaagg ccggcgatcg cggaacggtc ttccgtgaat ctaccggcct ggatatcact
    89641 ttttgttagg gcgaatcaca ggtgctgctt tatcgagtac gccgttgacg aacttatggc
    89701 tgtcttctgc gccgaacgat ttcgccagtt cgatcgcttc gttaatggcc actttgtatg
    89761 gcacatcgct acgtttagac agctcgtaca gcgcaatgcg cagtactgct ttttctacct
    89821 gtcccagttc ttccagcagg cgggacaggt atggcttcat cagtccgtcg aggtatgcgg
    89881 tgttagtcgc caccccggcc agcagctcac ggaagtacag gacgtcaacg tcttttacat
    89941 cctgttcagc caggaactgg tattcaacat cagcgatgtc gttctgggac aactgccagg
    90001 agtagagcgc ctggacggca cactcacgag cgcggcgacg agcagcaggt ttcacggatt
    90061 tccccttact aatttcaggc cttgatggct ttcaatacat taatcatttc aagcgcggtc
    90121 agtgcagctt ctgcaccttt gttgccagct ttggtgccag cacgttcgat cgcttgttca
    90181 atgctttcag tggtcagaac cccaaaagca accggaattt cgctgtcctg ggcaacatgc
    90241 gccaggccgt tgcttgcacc accagcgaca tattcaaagt gggcagtgcc accacgaata
    90301 accgtaccca gcgcaatcac cgcgtcgtat ttaccggttt tagccagtgc acccgccgcc
    90361 agcggcagct cataggcacc aggcacccaa acaacggtaa tgttttcatc ttttacctga
    90421 ccgatacgtt tcagtgcgtc aattgcacct tccagcaggc tgtcattgat aaagttgttg
    90481 aaacgcgcga tggtgatggc gacgcgagcg tccggggtag caacgttagc ttcaataatg
    90541 ttcattttct tccttcgggt tcgagtatgg ccccgcaggg gggcggattt tagcataata
    90601 tttcgtgcgc tgcttccctt tcgagccggg agatcatgca cccactaaat gcaggcaaac
    90661 atccgggcct acatgacgta tctctttgaa tttaaattgg ggggcgtcgg ctaatttctc
    90721 aagccctggc agcgagcata atccacgggc gtcgctgcct aatagtttag gtgcgatata
    90781 gacaatcagc tcatcgacta aacccacctg cagcaatgcg ccagcgagcg ttggccccgc
    90841 ttccacccag atgctgttaa tttgctgttt acccagttgc atcatcagta caaccagatc
    90901 cagatgacct ttatgctctg gaatcagcaa ggtacgcacc gtttccggcc actcacgaga
    90961 atcttcctgc gtacgcgcga accaggtttc gccgggctgc tgcacaatgc gatgttccgg
    91021 cgtcacgcga ttttggctat caatcacaat acgtaccggc tgacggagat tttgttgcgg
    91081 gtagagcacc tgagtttgtt catccagttc ggaccaacgc accgttaagg caggatcatc
    91141 cgccagcacc gtggcgctgc tggttaaaat ggcatgactt tgcgcgcgca gtcgttgtac
    91201 gtcgcgccgc gcctgagttg aagtgatcca ctggctttcg ccgctcgcca tcgccgtgcg
    91261 gccatcaagc gatgcgccaa gttttaactg aatataagga aagccggtgc gcatccgctt
    91321 gagaaagcct ttattcaatt gctcggcttc actcatcatc agcccgtggc tgacgtcaat
    91381 gccagcctgt tgcagacggt aaagtccacg cccagcgacc tgcgggttag gatcttgcat
    91441 cgctgcgacc acgcgcgcta cgccagcggc gatgagtgcg tcacagcacg gtggcgtacg
    91501 accatgatgg ctacagggtt cgagtgtgac ataggcggtc gcacctttgg ctttttcacc
    91561 cgccatacgc aacgcgtgta cttcggcatg tggttcaccc gctcgttggt ggtaaccttc
    91621 accgacaatt tcgccatctt tgacaatgac gcacccgaca ttcgggttgg gatgcgtggt
    91681 aaaacgtcct cgttgcgcca gctttagcgc ccgcgccatg taatactcgt cctgcacggc
    91741 ttagtcctcc aggcgcgcga tctcttcgcc aaattctttg atatcttcga aactgcggta
    91801 gacagaggca aaacggatat aggcgacttt atcgagcttt ttcaattgct ccatcaccag
    91861 attgccaatc atcttgctcg gtacttcgcg ctcaccggtg gcgcgcaact gcgatttaat
    91921 atgattgatt gccatttcaa cgtcatcgga actcaccgga cgtttttcca gcgcccgcag
    91981 cattccgctg cgcaatttct cttcattaaa cggttcacgc acgtcgttgc tttttacaac
    92041 acgcggcata accagctccg ccacttcaaa ggtggtgaaa cgttcattac acaccagaca
    92101 ctgccgacgg cggcgtacgg atgaaccctc gcccacgaga cgagagtcaa ttaccttagt
    92161 gtccacggcg aaacagaatg ggcaatgcat acggcgtcct gaccaggtgg ttaacggaaa
    92221 tctattttac cctgaactga cgatacaaca aaggcgcaac gcttttgaga taaaggatcg
    92281 atgctttcgc tgcttttacc ctctaccatt aggctaatta cgacgagaaa gggacgacct
    92341 atgaatacta acgtttttcg actgctcctg ctgggaagcc tgttcagcct tagtgcctgt
    92401 gtgcagcaaa gcgaagtgcg acagatgaaa cacagcgtca gcgcgctgaa ccaggagatg
    92461 acgcaactca atcaagaaac agtcaaaatc actcagcaaa acaggctgaa tgcaaaatcc
    92521 agcagtgggg tttaccttct gcctggagcg aaaacaccgg caagactgaa aagccagatc
    92581 ggtactttac gtatgtcgct ggtgaatatt acgcctgata cagatggcac caccctgacg
    92641 ctacgtattc agggtgagtc gaatgatccc ttgcccgcat tcagcggaac tgttgaatat
    92701 gggcaaattc agggaacaat agacaacttt caggaaatca atgtgcaaaa tcaattgatt
    92761 aacgcccctg ccagcgtcct cgcccccagc gatgttgata ttccgttaca gttaaagggg
    92821 atttctgtgg atcagttagg ctttgtacgt atccacgaca ttcaacctgt tatgcagtaa
    92881 acgtatttcg gggcgatttt gtgcgtcccg caacatcttt ccccgtcatt ttgttactct
    92941 gcttacatca cccagattga tagtaaaagt ttgcaacaag ggtgaaagtc agtacaatcc
    93001 ctgcccgaat gtgtgtaaac gtgaacgcaa tcgattacgt aaatgataga actgtgaaac
    93061 gaaacatatt tttgtgagca atgattttta taataggctc ctctgtatac gaaatattta
    93121 gaaacgcaat ttgcgccttt ttcactcccg caagggattt tcaaacagtg gcatacatat
    93181 gaaaaaaaca ttactggcag ccggtgcggt actggcgctc tcttcgtctt ttactgtcaa
    93241 cgcagctgaa aacgacaaac cgcagtatct ttccgactgg tggcaccaga gcgttaacgt
    93301 tgtcggaagc tatcacaccc gtttcggacc gcagatccgc aatgatacct accttgagta
    93361 cgaagcattc gctaaaaaag actggttcga cttctatggt tatgcggatg cgccggtatt
    93421 cttcggcggt aactccgatg caaaaggtat ctggaaccac ggttctccgc tgtttatgga
    93481 aatcgaacca cgtttctcca tcgacaagct gaccaatact gaccttagct tcggtccgtt
    93541 caaagagtgg tacttcgcga acaactacat ttacgacatg ggtcgtaata aagatggtcg
    93601 ccagagcacc tggtacatgg gtctgggtac cgacatcgat actggtctgc cgatgagcct
    93661 gtccatgaac gtctatgcga aataccagtg gcagaactat ggcgcagcga acgaaaacga
    93721 gtgggacggt taccgtttca aaattaaata ctttgtgccg attaccgatc tgtggggcgg
    93781 tcagctgagc tacatcggct tcaccaactt cgactggggt tccgatttgg gggatgacag
    93841 cggtaacgca atcaacggta ttaagacccg tactaataac tctatcgctt ccagccatat
    93901 tctggctctg aactacgatc actggcacta ctctgtcgta gctcgttact ggcacgacgg
    93961 tggtcagtgg aacgacgatg cagaactgaa cttcggcaac ggcaacttca acgttcgctc
    94021 taccggctgg ggtggttacc tggttgtagg ttacaacttc tgattatgaa aatgccggga
    94081 tttattcccg gcatttcaga ttgttaacaa cgtgcgcttt gttcatgccg gatgcggcgt
    94141 aaacgctttg tccgacccac aaaagcacgt aaattcaata tattgctgaa ataacgtagt
    94201 cctgataagc gtagcgcatc aggcaatttt acgttttaat cacttcttct tgttcatcat
    94261 cgctttcagg tcagcgaatg ggttgtactt cgcttcaccg acatctttct gcgcatcttc
    94321 ccctgcgata acggtcgtac catactgatc cgcttcggta tatttcgaat gctcatgatc
    94381 gtggcaatag agacaaagca attcccagtt actgccatct tccgggttat tggtatggtc
    94441 gtgatcaatg tggtgaacag taagttcacg caggttggaa tagacaaact cgcgggaaca
    94501 gcgaccgcag acccacggat agatttttaa tgctttttcg cgatagccgc tttctaaccg
    94561 cgcatagttt tttgggatga tagccatgaa aagttacctg gatgaaatgt agggttacgc
    94621 gcagtttccc aagatgcggg gattttcgca atctccatac atcaaaaaaa atcccgatct
    94681 tctgaccggg attttcaaca tcaacgggaa cttgattaag gcagaattga cggctgatcc
    94741 gccccttctt tttccacttt ctgctgcaac atgtgttcgc gcttcatacc cagtttcaga
    94801 gccaacgcag atgccacata gatggaagat gcagtaccga tggaaacacc gataagcatg
    94861 gtcagcgaga agccttccag taccggacca ccgaagaggt acagcatcag gataaccatc
    94921 aaggtagtac cggatgtgat caaggtacgg tgcagcgtct gggtcaagga cacgttaaag
    94981 atttcgtaag gcgtaccgcg acggatcttg cggaagtttt cacgaatacg gtccgatacc
    95041 acgatactgt cgttaagcga gtaaccgata accgacatca acgatgccac aatggtcagg
    95101 tcaatctcga tatggaataa cgacaaaata cccagcgtaa tgataacgtc gtgcgccagc
    95161 gcaataacca cccctgccgc cagtcgccac tcaaagcgga aacctacgta cacgaggata
    95221 gacagcagcg ctgccatcaa cgccatcgca ccggtttgcg caaggtctgc ccccacgctc
    95281 ggaccgacga actcaatacg cttcactgct gcattctgat tggtggattc gttaatcacc
    95341 ttcagaacct ggctgcccag cacctgaccg ccggtttcgc cttcagcagg cggcatacgg
    95401 accatgatgt cgtggctgct accaaagttt tgcagcattg gctcttcaaa accggctttt
    95461 tgcaatgcat cacgcattac gtcaatttca gccggttttt cgagcgtaat ttcgataacc
    95521 gtaccaccgg taaaatccag cccccagtta aagccgcgca cgcccataat aacgatagca
    95581 gcgattaaca gcagaccaga gatgccgaaa gcccagtagt cccagcgcat aaagtcatag
    95641 actttacggc cgtggtttag ttgttcaaca gtatattcct gtgccacatc gcactcctca
    95701 gattgacagc ttcttgacgc gcttgccgcc atatagcagg tttacgatgg cacgcgtacc
    95761 gacaatcgcg gtaaacatcg acgtcgccac accgataccg gtagtaatcg cgaacccttt
    95821 aattgccccg gtacccactg cgtacaggat gatgacttta atcagcgtgg tgatgttcgc
    95881 atcgaagata gaactgaatg cgccacgata accttcatca attgcctgtt gaacagtacg
    95941 tccgttgctc aactcttctt taatacgttc gttgatcagt acgttcgcat cgaccgccac
    96001 cgcaagggtt aagacgatac ccgcgatacc tggcatactc agcgttgcgc ctggcaacag
    96061 cgacataatg ccgacgatta agatcaagtt ggcaatcaga gcactggtcg caatcagacc
    96121 aaacttctta tagaagatga tcatgaacag aatagaaacc agcagaccgg caaggcaagc
    96181 ctccagcccc tgttcaatgt tctgcatacc cagggttggg ccaatggtac gttcttcaac
    96241 aatctgaatc ggcgcgatca acgcaccggc acgcagcagc agtgacagct gacgggcttc
    96301 gttcgggttg ttgatgccgg tgatacggaa gctgttaccc agacgagact ggatgttggc
    96361 gatgttaatc acctcttcct gtttcaccag aaccgcacga ccatttgcat ctttcttacc
    96421 gctgtctttg tactccacaa acagggttgc catcggtttg ccgatgttgt ccttagtgaa
    96481 gttagacatg atgttaccac cagcgctatc gagcgagatg ttaacctgcg gttggttgta
    96541 ttcgtcctgg ctggaagtgg agtcggtgat atggtcaccg gtcagaatta cgcgtttgta
    96601 cagcacaact ggctgacctt cgcgggtctg tttcacttca gagtcgcccg gtacgcgacc
    96661 agatgccgca gcggcctggt caacgttggt gtttaccaga cggaattcca gcgttgccgt
    96721 cgcacccaga atctctttcg cacgcgcagt gtcctgaata cctggcagtt caacaacgat
    96781 acggtcagca ccctgacgct gaaccaccgg ctccgccacg ccaagttggt ttacacggtt
    96841 acgcaggata ttaatgttct gctgcaccgc atattcacgc gcttcactca gacgagcatc
    96901 gctcattacc gcacgcagct ggttgctgcc ctggctgcta atcaccaggt ccggatggcg
    96961 cttgctcaga tacgcaatgg cttcatcacg agctttagca tcgcggaaag taatgctcag
    97021 gccgtagttg ttttctttac gaacggtggt atacgggatg cccttttcac gcagatcgct
    97081 gcgcaggcta tcgatatttt gttcctggag tttgccaagc gcggtgtcca tatccacttc
    97141 catcaggaag tgaacgccgc cacgcaggtc aaggccgagc ttcatcggct cagcgtgaat
    97201 agctgccagc cagcgcggcg ttgccggggc aaggttaagc gccacgacgt atttgtcacc
    97261 cataacgccc attaatgctt cacgagcgcg cagctgggtg tcagtggagt cgaagcgcgc
    97321 aagaatagcg ccctcttcca gtgccacaga cttagcagtt attttttctt cttgtaacgt
    97381 tttctggacc tggatcagcg tttgctcact ggcggcgact ccgcgcgcac cagtgatctg
    97441 aacagccgga tcctcaccaa acaggttggg aagcgcatac agcagaccga tgacaatcac
    97501 cacgatcagc atgacgtact tccacaaagg ataacggttt aacacggcaa ttcccttagg
    97561 gaaaaatttt aattacagcg ccttcatggt gcctttcggc aggacggcag ctacgaagtc
    97621 acgtttaata actacttcag tggtgtcatt cagcgcgata gcaatgtagc cgttttccgc
    97681 tactttggtt acgcggccaa ccaggccacc gttcgtcaga acttcatcac ctttggcaat
    97741 ggagtccatc agctttttgt gttctttggt gcgcttctgc tgtggacgca ggatcatgaa
    97801 atagaaaatc agaccgaata ccaccagcat caaaatcaaa gacatcgggc taccttgcgc
    97861 cggtgcaccc gttgccgcta ccgcatcaga aataaaaaag ctcattaaat ttccctcatt
    97921 attaatatta atcaacgttc aaaggtggta cttctcgccc ctgacgctgg taaaaatcag
    97981 ttacgaagct ctctaattta ccctcttcaa tagccttgcg taaacccgcc atcaaacgct
    98041 ggtagtaacg aaggttatga atggtgttga gtcgcgcgcc taatatttcg ttgcaacggt
    98101 caagatgatg caagtaagcg cgtgaataat tgcgacaggt gtagcaatca cactcaggat
    98161 cgagtgggcc agtatcgctc ttatacttcg cattgcggat tttcaccacg ccatcggtca
    98221 cgaacaaatg accatttcgg gcgttgcggg ttggcattac gcagtcaaac atatcgatac
    98281 cacgacgtac gccttcaacc aggtcttctg gtttaccaac gcccatcagg taacgcggtt
    98341 tgtctgccgg aatttgcggg catacatgct ccagaatgcg gtgcatatct gctttcggct
    98401 cacccacagc cagaccgccg acagcgtagc catcaaaacc gatatctacc agacctttaa
    98461 cagaaatatc acgtaaatct tcgtaaacgc tgccctgaat gataccaaac agcgcatttt
    98521 tgtttccgag actgtcaaaa cgctcacggc tacgcttcgc ccaacgcaga gacatctcca
    98581 tggagcgttt tgcgtaatcc cagtcagcag gatacggcgt acactcatca aagatcatga
    98641 cgatatccga accaagatcg tactgaatct ccattgattt ttcaggatcg aggaaaatcg
    98701 gatcgccgtt gatcgggtta cggaagtgca cgccctgttc ggtgatttta cgaatatcgc
    98761 caaggctgaa gacctggaaa ccgccggagt cggtgaggat cggccccttc cactgcataa
    98821 aatcgtgcag atcgccgtgc agtttcatga tttcctggcc cgggcgcagc cacaggtgga
    98881 aggtgttgcc gaggataatt tgcgcgccag tggcttcaac ttcttccggc gtcatccctt
    98941 ttacggtgcc gtaggtgcca acaggcataa aacaaggcgt ttccactacg ccacgatcaa
    99001 agaccaggcg gccacggcgt gcgcgaccgt cggtggtgtc cagttcaaat ttcatttttt
    99061 ctccactacg tcagaaaaac agtccaacgt tttaaaccag cgccgcggaa ttactccccg
    99121 acgcgctcat taattgcctg cggattgtac gtgataaaca tcgcatcacc gtaactaaaa
    99181 aagcgatatt tctcttctac cgctgcttta taggcgttca tggtgtgttg ataaccggca
    99241 aaggccgaaa ccagcataat cagcgtcgac tctggcaagt ggaagttcgt caccagcgca
    99301 tcgaccactt tgtactggaa gcccggatag ataaagattt gggtatcgtc gaagaacggt
    99361 tcaatgagat cgtttttcgc tgcctgagcc gcgctttcca gcgaacgtac tgaagtggtg
    99421 ccaaccgcaa tcacccggtt accgcgcgct ttcgccgcca gtaccgcgtc taccacatcc
    99481 tgcggtactt cagcgtattc cgagtgcatg atgtgatctt caatggtgtc gacgcgcacc
    99541 ggctggaagg tgcccgcacc aacgtgcaac gtcacaaacg ccatctccac gcctttggcg
    99601 cgcaattttt ccagcaaagg ctcgtcaaaa tgcagaccag cggtcggggc tgcaaccgcg
    99661 cccggttttt cgctataaac ggtttgataa agttcgcggt cagcgtcttc gtccggacgg
    99721 tcgatatacg gcggcagcgg catatggccg atactgttga ggatatccag taccgaacga
    99781 tcatcattga attcgacttc aaacagtgcg ccgtggcgcg cggtcattgt tgcgttaata
    99841 ctttcgtcat cgcccagcag cagttctgcg ccaggttttg gcgctttcga ggcgcgaata
    99901 tgcgcaagaa tgcgtttgtc gtcgagcatc cgctcaacca gcacttcaat cttgccgccg
    99961 ctggctttac gcccaaacag gcgcgccggg atcacgcggg tattattaaa aaccagaaga
   100021 tcgccggggt tgagcttatc aagtaaatcg gtgaaagtac cgtgcgtcag cgcgcccgtc
   100081 ggcccgtcca gcgacagtaa acgacagcta ctgcgttcag gcatgggata gtgggcaatc
   100141 agggattcgg gcaattcaaa ggagaaatcg gtaacgcgca tgacactgac tcagactaaa
   100201 ataagaggcg ggtagtctag tgccggggcg ctctccctgc aacctttacc cccttttgga
   100261 tagaatataa tcgatgaatt ttttagctca cctgcattta gcccatctcg cggaaagctc
   100321 gctttccggc aatttactgg ctgatttcgt acgcggaaat cctgaagaaa gttttccgcc
   100381 cgacgtcgtg gctggcattc atatgcatcg acgtatcgac gtattaaccg acaatctgcc
   100441 ggaagtccgc gaagcacggg aatggtttcg tagtgaaact cgccgcgttg cgcctattac
   100501 gctggatgtc atgtgggatc actttctttc ccgccactgg tcgcagctgt cgccggactt
   100561 tccgctacag gaatttgtct gttatgcccg cgagcaagtg atgacgattt tgccggactc
   100621 accgccacgt tttatcaatc tgaacaatta cttgtggtca gagcagtggc tggtgcgcta
   100681 tcgcgatatg gatttcatcc agaacgtgtt aaacggcatg gcaagccgcc gcccacgtct
   100741 ggatgccctg cgtgactcct ggtacgattt agacgctcat tatgacgccc tcgaaacccg
   100801 cttctggcag ttttatccgc ggatgatggc gcaggcgtca cacaaggcgt tataaaacgt
   100861 tagttcatcc ataccgtagc cgaaatggca ggcaaagcca gaatcccgtt tgtcagttgc
   100921 ccatggcctt ctttgcgttg ccattgcgcg acattaagaa acggtgacgc ggggagcacc
   100981 acttcacagg cctcgccacg gttgattgcc accagtacac gttgctgatt cagcacgcgg
   101041 acaaatacca ctacgttatc ttccgcatac agcacctgac agccgccacg acgcagcgcc
   101101 tgacttttct tacgcagcgc aatcattcgc tggtacagcg cgaataacgc cgtatcctgc
   101161 ttttccacct gccaggggaa cggtttacgg caaaacggat cgtttttgcc atccagtcct
   101221 acttcatcac cgtaataaat gcacggtaca ccaggccagg tgaacagcca gaccaccgcc
   101281 agcggcaggc gcgcaatatc ccgaccgagc agcgttttaa atcgcgcagt atcgtggctg
   101341 tcgagctgat taaacatacg taattgttgt tgatgagaaa gccctgcgcg gtaattatcc
   101401 atccaggcca tacaggtttg ggcatcaatt tgctgcggat cgtaagagat atcggtattg
   101461 gcaagaaatc cccacaacgg gaatgtgaag ccacgatagt tcatggcggc atcttccaca
   101521 tcggcctgta accattgccg tgcatcgcca aaatgttcgc cgacaatata cgcttccggc
   101581 tgggtttctt tcgccgcttc ggtgatccca gcaacgtgct gcatattatt gcgcgcccca
   101641 cccgcctccc ccagcatatg caccacatcc agccgccagc cgtccatact ccacggcgct
   101701 ttcagccaat ggcggacaat actgtcttcc ccgcgataaa tttcattcac cagactttcc
   101761 gactgataat ccagcttcgg caagctggca tagccaagcc agtcgagcgc cgtgccatca
   101821 tcactaaacg agtaccagtc gcgccagggc gattcagggt tgtgacaagc tccccccgtg
   101881 ccacgattgt gcctgtcaaa ccaggcatgg gaatcgccac tgtggttaaa cacgccatcc
   101941 agcaccagcc gcattcccag ctgctgcgta ttgtggcgta agcgcagcaa cgccccatca
   102001 ccgccaaact gcggatcgac atggcgataa tcctcggtat cgtatttatg tacgctggga
   102061 gctttaaaca ccggattgag atacagcgcc gtcacgccaa gctttttcag atacggcagt
   102121 ttttcgctta tcccgtccag atcgccgcca tagaacgttg atccgcccgc ctgcgccgtg
   102181 accggttcat cccagtcacg caagatgatc tcttgtccgg ctgcatgatg gtaatagaca
   102241 tgatcctgtt cagcttcacg aggaagacta cgcgcaaaac gatcagggaa gatctgataa
   102301 aaaatctgat ccgcagccca ttgtgggccg atatccggta catcgacggc aaactgctcc
   102361 agtcgtgccg gcggcattcg gctgaagccc tgcggtgtaa accaacgctg gcgatcgtgc
   102421 cacagcagtt tgaaactgta acgccgccgg ggttgtccgc tggagagatc aatcgccgca
   102481 cgccatgcgg tgacgccagg ctgctgctga ctgcgctgct tatgcatcga tactgacatt
   102541 tcttcgttat cgtgttctgt acgcagcata atgcgctgcg gtgggtcttc gcccgtcagc
   102601 cacagtgtaa tgagcagttg atctttgctt tgtttaacaa atgggggcac cggcaggtgc
   102661 catgcattta acatcataat tcccctgtga tgaaaatctg atcaccttgc catagcctaa
   102721 tgcaggatca ctcatcatct gaaggatatt tgggggagga ggacgggggc ggataacttt
   102781 cggaatagcc ggatcaggat ttcctcctga accggcttac agaacgcaag gattactggt
   102841 tttcagccag ctgacgatcg tggcggcgtt taaacatcca gccaatcaac agcacaacaa
   102901 tccacgcgaa accgacatac agcgagatac gcgtatccgg gtgataacca atcaacccga
   102961 taataaagag caggaaaatc aaaccgccga tggtcgttgc taccccaccc ggcactttaa
   103021 atttcagcgc cttaacttct tctggcggca aacggcgacg gaaggcaatt tgcgacagca
   103081 ggatcataat ccacacccac accgtggcga aggttgccag cgaagcgatc accaggaaga
   103141 cgttttccgg catgatgtag ttcagataca ccgcaaacag cagcgcggta gtcatcacca
   103201 gcaccgtaac ccacggaata ccgcgacgcg acgttttgct gaaaattttc ggcgcgctgc
   103261 cctgctctgc cataccgtgg agcatacggc ctacgccaaa tacgtcactg ttaattgccg
   103321 acagcgaagc agtcagcaca acaaagttaa gaatgctggc ggcaaaggta atgcccatat
   103381 gctggaacgt cagcacgaac gggctaccgg cagtgccaac ctgattccac gggtagatag
   103441 acataatgac gaacagcgta ccgacgtaga acaccagaat acgcatcggc acggagttaa
   103501 tcgcacgcgg tatcgatttc tcaggatctt tcgcttcacc ggcggtaatc ccgataattt
   103561 cgatcccacc gtaagcaaac atcaccattt gcaacgacat caccatccca agccagccgt
   103621 tactgaagaa gccgccgttg ctccacaggt tatgaatacc ggtcggttgc ccgccgttgc
   103681 caatccccca gatgatgatg ccgaaaccgg cgacaatcat gatgatgatg gtggcgactt
   103741 taaagaacga gaaccagaat tccagctcac cgaagacctt cacgctcatc aggtttacgg
   103801 cgcaaatgat cagcaccacg ctcagtaccc aaatccagtg cggcaccgtc gggaaccaga
   103861 cacccatata gataccaaaa gcggtcacat cggcgatggc gacaataagg atttcaaagc
   103921 aataggtcca gccggtaatg taacctgcca gcgggccgag gttttcctgc gcataacgcg
   103981 agaaagagct ggctgccggg ttatgtaccg acatttcccc cagcgcacgc ataatgatat
   104041 acgccgcgat accaccgata atataggcca acaacacgct cggaccggcc attttgatgg
   104101 cgtctgccga accgtaaaac agcccggtgc caattgctga acccagtgcc ataaagcgta
   104161 tgtggcgggt acttagccca cgctttagct tgttcttact ttccatcaat tcctaaccca
   104221 tcaacacaat aaaaaaccac ggggcatcgc agccccgtgg ttaaaacaaa tgttcagtga
   104281 tttagtgagc gctggaagtc acctgacgac ctgccgcgcg atcccagata atggccagaa
   104341 ccaccatcac cactgttggc attaaccacg ccagaccttg ttcggccagc ggtaaacgct
   104401 gcgcccagga cggtaagata tcgctgaatg cagatgcttt gatcccgtcg agaataccaa
   104461 aaagcaggct gataaacatc ggcggagcaa tcacgcggga cgaattatgc caccatgagc
   104521 gtgtaaaact taatacaacc agtgcgatac acggcggata aatagcggtc agcaccggta
   104581 cggagatctg gatcagctgg cttaagccga ggttagaaac caccatcgag aagccgccga
   104641 ggataaacac cagcgtacga taagagagcg gtacgtactg ggcaaagaat tctgcacaag
   104701 cacaggtcag gccaactgcc gttaccaggc aggcgatgaa gattaacgcc gccagcagga
   104761 agctaccgcc gccgccaaag gtgtgctgaa cgtaagcatg cagaatagca gcgccgtttg
   104821 cagactgatc gaccagcgac gcgctgtctg aacccagacg gaacagcgcc aggtacagca
   104881 gagtcagacc aacacccgcc atcaggccag cccagacggt ataacgggtc agcagacgcg
   104941 cttcggtaac gccacgagaa cgcgccgcgt taacaataac gataccaaac accattgcgc
   105001 ccagcgtatc catggtcaga tagccgttaa cgaagccgtt agaaaacgca gcgttttgat
   105061 aagcctcagt cgccgtgctg atagaacccg ccggccagac aatcgcggca acagacagga
   105121 tgaccagcgc gataattttc agcggcgcaa ggaagttgcc cacggtatcc agcagcttgc
   105181 ccggatagag cgaaaccaga ataacgatag cgaaatagac caggctgtag ataaacagcg
   105241 gcagcgcgga atcaccagtc agcggcgcaa tccccacttc aaaggaaacg gtagctgtac
   105301 gcggcgtagc gaaaagcggc cccaccgcca ggtaacaaac cgttgccagc agtacgccag
   105361 cgactttacc gattggcgtg ctgaggctgt caacaccgcc gccaactttt gccagcgcca
   105421 ctaccgttag taccggcaga ccaacggcag taatgaggaa gccgaatgcc gcagtccaga
   105481 cgtgttcgcc tgcctgcaag ccgaccattg gagggaaaat aatgttacct gcgccgacga
   105541 acaacgcaaa tgtcataaag cccagagcga tgatatcgcg cgatcttaat tgatgggtca
   105601 taaatcatac tgcctgtgga tgtggtgttg taacgttaaa tttttgtgcc aatccctggg
   105661 gatgatacag cggtatattt aaacaatttt agcgggaaat actcccaacc aggcgcggcg
   105721 aagaatagtt tttcgattta ccgcgttaat gcagtcagta tgacagcacc tgaagcgcaa
   105781 tttaaacgct tataacgttt taaagcaagg agggatctaa aaaccagagg tatatagcga
   105841 taagaaatca ccaaccagta taaaacacta tttccgtgaa aaagacatgg ctaatcatgc
   105901 gaacaaaaaa tcaccaaccg ttgtaaaatc taacgcccgt attttgactg caaagaaaat
   105961 aagccagcat cggctggctt atggcaataa aagatgacaa aggcggatta atcgctgttt
   106021 ttggcaatta aacgttccgg gataacaaaa ctgaaacgtg ttccttttcc tactgtactc
   106081 tcaatattca ggcgactttc gtgatgattc accgcatgtt tcacgatcgc taaccctaat
   106141 ccgctaccgc cggtttgccg ggaacgcgct ttatcaacgc gataaaaacg ctcggtcagg
   106201 cgcggaatat gctccggtgc aatgcccggt ccgttatctt caacgctaaa ttcggcaccg
   106261 tgcggcactc gctgccagcg tacggtgata tgcgtgcctt ctggagtatg attcacggcg
   106321 ttatagacca ggttcgaaat cgcactgcgt agctgatctt cgttgccaga cactttgagg
   106381 ccgttatcta tctcaaaggt aaatgtctgt tttttctgac tcagagtctg agcctcacgc
   106441 tcaacaacgc gcagcatcat cggcacatca accttttcat tgagcaaatg cgtcggtgcg
   106501 gcttctattt tcgacagcgt cagcaactgc ttcaccagcc cttccatccg ctgggtctgc
   106561 tcgcgcatgg tgtgcaacgc tttttcgcgt accgcgcctt ccagcggctg ctcatccatc
   106621 atctccaggt aaccctgtaa cacggtcaat ggcgtacgta actcatggct cacgttggca
   106681 aaaaagttac gccgcgcccc ttccagttga tgcatttgcg tgacatcacg cgccaccatc
   106741 agcaactgtt tgtgggtata aggcatgacg cgaatttcca gatgccgccc ggtgttgagc
   106801 accagattga gcgggcgaga aaaatcacgc gttttcagat attgcgtaaa ctccgggtaa
   106861 cgcagcaggt taaggatgtt ctgcccgtta tcttccggcc agcgcaaacc aagaatttgt
   106921 tgcgccagac cgttacacca gaaaataccg ccctcttcag tggtcagcac cactgcgtcg
   106981 ggcagcgact ccgcgccgct acgaaagcgt ttaatcagat tgcccagttc acggcggcgt
   107041 tttttatttc gcagctgcat ctggtgtaag ccgtatagta gcggttccca gctaccacgc
   107101 cccggtggcg gggtcatact acgatccacc cacagccacc atgaaaggcg caataaattc
   107161 cagaaatgcc agataagcag tcccgttacc gatgccagca aaaaccaggg caggtaacca
   107221 aaaaatgcac ccaggatgaa agccgggaag cagcaaagta gcagctccag caccagcctt
   107281 ttccacgaca gccgttccag cacgtaagat actccagtta agaaatcata agccctgctc
   107341 tgcgtccgat gagcaaggcg ttaaaagcgg gttgaaaaac gatatcctgt accgcgcacg
   107401 gtctgcacca tgcggtcatg cccgcctggc tccagtgctt tacgtaggcg acgaatgtgg
   107461 acatcgaccg tacgatcttc cacatacacg ttagttcccc agacgtggtt taacagctgc
   107521 tcgcggctgt acacgcgctc aggatgcgtc ataaaaaagt gcagcagttt aaattctgtc
   107581 ggccccatct ccagcggctc ttcgcccgcc atcactcggt gagatgtcgg gtcgagactt
   107641 aatccctgca tctcaatcac ctcttccacc gccattggcg aaatacggcg cattaccgct
   107701 ttgattcgcg ccaccagctc cttcggcgaa aacggcttgg tgatatagtc atccgcgccg
   107761 gtttcaaggc cgcgcacgcg atcttcttct tcccctctgg cggtcaacat caccactgga
   107821 atatcccggg tcatcgactc gcgcttgagg tgtttgatga actggatacc ggagccgcca
   107881 ggtaacatcc agtcaaggag aattaaatcc ggccagggtt cattcagttg attcacagca
   107941 ctgtcataat cttccgcttc gaccggctga aagccatttt gttcgagcac gaagcagacc
   108001 atttcgcgaa ttggagcttc atcttctacg accagaatac gtctcgccat gatttgccct
   108061 gttgtaataa ataggttgcg atcattaatg cgacgtcatt atgcgtcaga tttatgacag
   108121 atttatgaaa agctcgtcgc acatatcttc aggttattga tttccgtggc gcagaaaaaa
   108181 gcaaatggca catctgtttg ggtataatcg cgcccatgct ttttcgccag ggaatcgtta
   108241 tgcgcatcct tcacacctca gactggcatc tcggccagaa cttctacagt aaaagccgcg
   108301 aagctgaaca tcaggctttt cttgactggc tgctggaaac agcacaaacc catcaggtgg
   108361 atgcgattat tgttgctggt gatgttttcg ataccggctc gccgcccagt tacgcccgca
   108421 cgttatacaa ccgttttgtt gtcaatttac agcaaactgg ctgtcatctg gtggtactgg
   108481 caggaaacca tgactcggtc gccacgctga atgaatcgcg cgatatcatg gcgttcctca
   108541 atacgaccgt ggtcgccagc gccggacatg cgccgcaaat cttgcctcgt cgcgacggga
   108601 cgccaggcgc agtgctgtgc cccattccgt ttttacgtcc gcgtgacatt attaccagcc
   108661 aggcggggct taacggtatt gaaaaacagc agcatttact ggcagcgatt accgattatt
   108721 accaacaaca ctatgccgat gcctgcaaac tgcgcggcga tcagcctctg cccatcatcg
   108781 ccacgggaca cttaacgacc gtgggtgcca gtaaaagtga cgccgtgcgt gacatttata
   108841 ttggcacgct ggacgcgttt ccagcacaaa actttccacc agccgactac atcgcgctcg
   108901 ggcatattca ccgcgcacag attattggcg gcatggaaca tgttcgctat tgcggctctc
   108961 ccattccact gagttttgat gaatgcggaa agagtaaata tgtccatctg gtgacatttt
   109021 caaacggcaa attagagagc gtggaaaacc tgaacgtacc ggtaacgcaa cccatggcgg
   109081 tgctgaaagg cgatctggcg tcgattaccg cacagctgga acagtggcgc gatgtatcac
   109141 aggagccgcc tgtctggctg gatatcgaaa tcactgctga tgagtatctg catgatattc
   109201 agcgcaaaat ccaggcatta accgaatcat tgcctgttga agtattgctg gtacgccgga
   109261 gtcgtgaaca gcgcgagcgt gtgttagcca gccaacagcg tgaaaccctc agcgaactca
   109321 gcgtcgaaga ggtgttcaat cgccgtctgg cactggaaga actggatgaa tcgcagcagc
   109381 aacgtctgca gcatcttttc accacgacgt tgcataccct cgccggagaa cacgaagcat
   109441 gaaaattctc agcctgcgcc tgaaaaacct gaactcatta aaaggcgaat ggaagattga
   109501 tttcacccgc gagccgttcg ccagcaacgg gctgtttgcc attaccggcc caaccggtgc
   109561 ggggaaaacc accctgctgg acgccatttg tctggcgctg tatcacgaaa ctccgcgtct
   109621 ctctaacgtt tcacaatcgc aaaatgatct catgacccgc gataccgctg aatgtctggc
   109681 ggaggtggag tttgaagtga aaggtgaagc gtaccgtgca ttctggagcc agaatcgggc
   109741 gcgtaaccaa cccgacggta atttgcaggt gccacgcgtt gagctggcgc gctgcgccga
   109801 cggcaaaatt ctcgccgaca aagtgaaaga taagctagaa ctgacagcaa cgttaaccgg
   109861 gctggattac gggcgcttca cccgttcgat gctgctttcg caggggcaat ttgctgcctt
   109921 cctgaatgcc aaacccaaag aacgcgcgga attgctcgag gagttaaccg gcactgaaat
   109981 ctacgggcaa atctcggcga tggtttttga gcagcacaaa tcggcccgca ctgagctgga
   110041 gaagctgcaa gcgcaggcca gcggcgtcgc gttgctcacg ccggaacaag tgcaatcgct
   110101 gacagcgagt ttgcaggtac ttactgacga agaaaaacag ttacttaccg cgcagcagca
   110161 agaacaacaa tcactaaact ggttaacgcg tctggacgaa ttgcagcaag aagccagccg
   110221 ccgtcagcag gccttgcaac aggcgttagc cgaagaagaa aaagcgcaac ctcaactggc
   110281 ggcgctcagt ctggcacaac cggcacgaaa tcttcgtccg cactgggaac gcatcgcaga
   110341 acacagcgcg gcgctggcgc atactcgcca gcagattgaa gaagtaaata ctcgcttaca
   110401 gagcacaatg gcgcttcgcg cgagcattcg ccaccacgcg gcgaagcagt cagcagaatt
   110461 acagcagcag caacaaagcc tgaatacctg gttacaggaa cacgaccgct tccgtcagtg
   110521 gaacaacgaa ctggcgggtt ggcgtgcgca gttctcccaa caaaccagcg atcgcgagca
   110581 tctgcggcaa tggcagcaac agttaaccca tgctgagcaa aaacttaatg cgcttgcggc
   110641 gatcacgttg acgttaaccg ccgatgaagt tgctaccgcc ctggcgcaac atgctgagca
   110701 acgcccactg cgtcagcacc tggtcgcgct acatggacag attgttcccc aacaaaaacg
   110761 tctggcgcag ttacaggtcg ctatccagaa tgtcacgcaa gaacagacgc aacgtaacgc
   110821 cgcacttaac gaaatgcgcc agcgttataa agaaaagacg cagcaacttg ccgatgtgaa
   110881 aaccatttgc gagcaggaag cgcgcatcaa aacgctggaa gctcaacgtg cacagttaca
   110941 ggcgggtcag ccttgtccac tttgtggttc caccagccac ccggcggtcg aggcgtatca
   111001 ggcgctggag cctggtgtta atcagtctcg attactggcg ctggaaaacg aagttaaaaa
   111061 gctcggcgaa gaaggtgcgg cgctgcgcgg gcaactggac gccttaacaa agcagcttca
   111121 gcgcgatgaa aacgaagcgc aaagcctccg acaagatgag caagcactta ctcaacaatg
   111181 gcaagccgtc acggccagcc tcaatatcac cttgcagcca caggacgata ttcaaccgtg
   111241 gctggatgca caagatgagc acgaacgcca gctgcggtta ctcagccaac gacatgaatt
   111301 acaagggcag attgccgcgc ataatcagca aattatccag tatcaacagc aaattgaaca
   111361 acgccagcag cagctcttaa cggcattggc gggttatgca ctgacattgc cacaggaaga
   111421 tgaagaagag agctggttgg cgacacgtca gcaagaagcg cagagctggc agcaacgcca
   111481 gaacgaatta accgcgctgc aaaaccgtat tcagcagctg acgccgattc tggaaacgtt
   111541 gccgcaaagt gatgatctcc cgcacagcga agaaactgtg gcgctggata actggcggca
   111601 ggttcatgaa caatgtctcg cattacacag ccagcagcag acgttacagc aacaggatgt
   111661 tctggcggcg caaagtctgc aaaaagccca ggcgcagttt gacaccgcgc tacaggccag
   111721 cgtctttgac gatcagcagg cgttccttgc ggcgctaatg gatgaacaaa cactaacgca
   111781 gctggaacag ctcaagcaga atctggaaaa ccagcgccgt caggcgcaaa cgctggtcac
   111841 tcagacagca gaaacgctgg cacagcatca acaacaccga cctgacgggt tggctctcac
   111901 tgtgacggtg gagcagattc agcaagagtt agcgcaaact caccaaaagt tgcgtgaaaa
   111961 caccacgagt caaggcgaga ttcgccagca gctgaagcag gatgcagata accgtcagca
   112021 acaacaaacc ttaatgcagc aaattgctca aatgacgcag caggttgagg actggggata
   112081 tctgaattcg ctaataggtt ccaaagaggg cgataaattc cgcaagtttg cccaggggct
   112141 gacgctggat aatttagtcc atctcgctaa tcagcaactt acccggctgc acgggcgcta
   112201 tctgttacag cgcaaagcca gcgaggcgct ggaagtcgag gttgttgata cctggcaggc
   112261 agatgcggta cgcgataccc gtaccctttc cggcggcgaa agtttcctcg ttagtctggc
   112321 gctggcgctg gcgctttcgg atctggtcag ccataaaaca cgtattgact cgctgttcct
   112381 tgatgaaggt tttggcacgc tggatagcga aacgctggat accgcccttg atgcgctgga
   112441 tgccctgaac gccagtggca aaaccatcgg tgtgattagc cacgtagaag cgatgaaaga
   112501 gcgtattccg gtgcagatca aagtgaaaaa gatcaacggc ctgggctaca gcaaactgga
   112561 aagtacgttt gcagtgaaat aactattcag caggataatg aatacagagg ggcgaattat
   112621 ctcttggcct tgctggtcgt tatcctgcaa gctatcactt tattggctac ggtgattggt
   112681 agccgttctg gtggttgtga tggtggtatg aaaaaagtca ttttatcttt ggctctgggc
   112741 acgtttggtt tggggatggc cgaatttggc attatgggcg tgctcacgga gctggcgcat
   112801 aacgtaggaa tttcgattcc tgctgccggg catatgatct cgtattatgc actgggggtg
   112861 gtggtcggtg cgccaatcat cgcactcttt tccagccgct actcactcaa acatatcttg
   112921 ttgtttctgg tggcgttgtg cgtcattggc aacgccatgt tcacgctctc ttcgtcttac
   112981 ctgatgcttg ccattggtcg cctggtttcc ggctttccgc atggcgcatt ttttggcgtc
   113041 ggcgcgatcg tgttatcaaa aattatcaaa cccggaaaag tcaccgccgc cgtggcgggg
   113101 atggtttccg ggatgacagt cgccaatttg ctgggcattc cgctgggaac gtatttaagt
   113161 caggaattta gctggcgtta caccttttta ttgatcgctg tttttaatat tgcggtgatg
   113221 gcatcggtct atttttgggt gccggatatt cgcgacgagg cgaaaggaaa gctgcgcgaa
   113281 caatttcact ttttacgcag cccggccccg tggttaattt tcgccgccac gatgtttggc
   113341 aacgcaggtg tgtttgcctg gttcagctac gtaaagccat acatgatgtt tatttccggt
   113401 ttttcggaaa cggcgatgac ctttattatg atgttagttg ggctagggat ggtgctgggg
   113461 aatgtgctaa gtggcaggat ttcaggacgt tattcaccac tgcgcattgc agcagtaact
   113521 gactttatca ttgtactggc actgctgatg ctttttttct gcggcggcat gaaaacaacg
   113581 tcgcttattt ttgcttttat ttgttgcgcg ggattatttg ccctttcagc acctctgcaa
   113641 atattgttac tacaaaacgc caaaggcgga gagttattag gtgccgcagg tgggcaaata
   113701 gcgtttaacc tcggtagcgc cgtcggcgca tattgcggag gtatgatgct gacgctgggg
   113761 ctggcatata attacgtggc gctgcctgcc gccctgcttt cgtttgctgc gatgtcatcg
   113821 ttgctgctgt atggtcgcta taagcgccag caagcggcgg atagtccggt gctggcgaaa
   113881 ccactggggt agattactgt cacggtgcgc gttgcttatt gccggatgcg gcgtgaacgc
   113941 cttatccgcc ctacgcggtt ccggcacatt ttgtaggcct gataagacgc ggcaagcgtc
   114001 gcatcaagca tgatgcgcca attgcctacg ttttttactc ttgtggccat aaccacgcag
   114061 cgccgcgtac gccgctggaa tcaccgtgct tcgccttacg caccggcgtt tcacattcgc
   114121 cgccgaagac aaattgttta atcaactgcc caaccgtttg atataaacgg tctacattgc
   114181 tcatcccgcc ccccaggaca atcacatccg gatcgagaat attcacgaca tgtgccagcg
   114241 attttgccag ccgcagctcg tagcgacgca atgccagttc cgctaccgga tcgctttctt
   114301 caaccaggcg gataatttca ctgcctttca gcgcatgtcc gctcaaacga cgataatctg
   114361 tggcaaatcc cgtgcccgaa ataaaggttt caatacaacc ttgtttaccg caataacaag
   114421 ggacttcctc gcgataacgc agttcgtctt cgtccatcca cggtagcgga ttgtgtcccc
   114481 actcgcctgc cgtgccattg ccgccgatat gcgcccgccc attgaatgcc acgcccgcgc
   114541 cgcatcccgt gccgataatc acggcaaata ccgtctgtgc tcccgctgcc gcgccatcta
   114601 ctgcttctga aacggccaga cagttggcgt catttgccag ccgcacttcc cgctgcaacc
   114661 tcgcgcttaa gtctttatcg aatggctgac cgttgagcca ggttgaattg gcattcttaa
   114721 ccacaccggt gtaaggcgaa attgagccag gaatgcccat acctaccgtt ccgcgctgcc
   114781 ctgtcgcctg ctccgccata tcaaccaacg tggcgatcgt ttcaatagtc tgccggtaat
   114841 catcacgcgg cgtgggcaga cgatggcggt acaactgctc ccctgcatcg cccagtgcaa
   114901 tcacttcagt tttggtgccg cctaaatcga tacctatacg cacggtactc tccttatttt
   114961 tttcaatatc aatagcgtag agacggacaa ccggattggc aatgcaaggc cgccgacaat
   115021 tcgttatcat gcccgctaaa tttaacgaca aggccgtgga aattatcatg ctgtggttca
   115081 aaaatttaat ggtttaccgt cttagccgcg agatttcgct gcgtgcagaa gagatggaaa
   115141 aacagctagc ctcgatggca tttaccccat gcggcagcca ggacatggcg aagatgggct
   115201 gggttcctcc gatgggatcg cacagcgatg cgttaacgca cgttgccaat ggtcaaattg
   115261 ttatctgcgc gcgcaaagaa gaaaaaatcc tcccgtctcc ggtgattaag caggcgctgg
   115321 aagcgaaaat cgccaaactg gaagcggaac aggcgcgtaa gctgaagaaa accgaaaaag
   115381 attcgctgaa agacgaagtg ctgcactctc tgttgccgcg tgctttcagc cgttttagcc
   115441 agacaatgat gtggatcgac acggttaacg gtttgattat ggtggactgc gccagtgcca
   115501 aaaaagcgga agatacgctg gcactgctgc gtaaaagcct ggggtcgtta ccggttgtac
   115561 cattgagcat ggaaaacccg attgaactga cgttgaccga atgggttcgc tccggtagtg
   115621 cggcacaggg cttccagctg attgatgaag ccgagctgaa atcgttgctg gaagatggcg
   115681 gcgtgatccg cgcgaagaaa caagatctga ccagcgaaga gatcaccaat cacattgaag
   115741 ccggaaaagt ggtgactaaa ctggcgctcg actggcagca gcgcattcag tttgtgatgt
   115801 gcgacgatgg ttcgctcaag cgtctgaagt tctgcgacga gctgcgcgat caaaacgaag
   115861 atatcgaccg tgaagatttc gcccagcgtt ttgatgccga tttcatcctg atgactggtg
   115921 aactggcagc gttaattcaa aacctgattg aaggattagg tggcgaagca caacgttaat
   115981 tgctgatttt cctttaatgc cggatgcgac gcctgccgcg tcttatccgg cgtacgaagc
   116041 cacaccaggc atataattat tcgctacggc gggcaataat ttttagcgca gcaatattat
   116101 gcgttttatg ctgtaacttg ctccatggac gttgtgtcat tgtttttcct caagccagtg
   116161 acgcgcttca ctgcgaattt tccgcattgc cccggttttc actaaatccc gtaacagcga
   116221 aagatcgggt tgttcgacaa ataagagtaa tgatggatcc tcttttaacc acgtcgtttt
   116281 cacatcggca gcgagctgtg gattattcat agctagcgac cgatgccgag actcggtcaa
   116341 tgtcgttaac aacgacgccg gggtatgtgc gttgcgtaat gccgtttggc gcaaatgatc
   116401 attgcgactt tgcagcaatg cacgccacca ttcatcatct gatttatctt ttatcgtagc
   116461 cagttccgca acaatatctg gagatcttca ctgatattta tatcaacctt gatgaattat
   116521 gaatataccg gaaattgaaa aaatcgcagc aaaggaaata ttattatggg ttaaagagag
   116581 gatatttcag aaaaatgccc tcccgttcaa ggggaaggcg aggaattaca gatagcggca
   116641 cagataagag gtgggttcgg caacttgcag atgaaactca ctgtgaccgg gaacattaaa
   116701 caccgaaccg gcttcataca cctgccagtc ggtcgcgtca ggcagtaaca cattcagcgc
   116761 gccactgatt accgtcattt cttccggctc agcggtgctg aaggtgtatt cgccttcaac
   116821 cataacaccc acgctggcgc gaccagtgct gctgctggaa aagccgattg atttcacttt
   116881 gccggaaaag tactcattac tttgaagcat aaactggccc tgtttggtag ttgaacatct
   116941 acttcactat aggggccaga ggcgctggct gtcacgcaaa attacaccag taattccgca
   117001 gccagccgtg caatcaatac gttagacagc aagacaggaa catcgagctg tttttgcagt
   117061 aaatcgcgat gacgttggtg aaatcctaaa caatccagca tgatgacatc agcccctttt
   117121 gccagtaatt ctttcccggc atcaatgatt ttttgttctg aatcatgaat ggggttaccc
   117181 aatgaaaata ccggcgattt ctgcaaaatt tgccattttt gcgcctgaac gggcagcatc
   117241 tcctcaaccg gaacgataac ccccacctga tgatcttcaa caatagagga aaccagtgga
   117301 ggcaatattc gcgacggctc aagaaagatc gtattacgcg cagtcatact actaatgttt
   117361 gctgtactca ttaataaaat gacgtcataa ccctgattat cgagcacttc aaccacacct
   117421 tgcaggtctc gctccacttt acgacgcgaa acatgggcca gctggatgtc atttaataat
   117481 gtgagaatgg tgtcttcgcc tgcttctggc gcgtactccg ccatcacttc ttcacgactt
   117541 aacttcccca gcaggctatg atgggaaata ttatcttcgt caatgtattc cgtcaggagc
   117601 ggcaaaacct cctgcatagg tacaatgccg atggtcagga tcgccaacga cgcactcatt
   117661 gttcatccac cttacttttc tttcgtcgtt aattaccggg caagtgtgaa gcaccactgc
   117721 tgacacttac ttgtgctaca aatgacaaaa agcgtagcag cagacgtgca cggcataatg
   117781 taaagattcc aaatgattcc agtaatggat tgttattgtt taatattcta attattagaa
   117841 aaacatgaat tatgaaaaat gtgacgcaga tcccttgtag tggcactcag aatcccttcc
   117901 gagcagtctg atgcggtcac tctttgtcag ggtcctcata gcgttttttc gcatccatcg
   117961 cttcctgagc cgtcggatgt tcactgatca acgagtctgg tttaggatga tcggctctga
   118021 gttggtacca ggttaccgtc tgtcctggct ttcctttttc aatcgtcact atatatgctt
   118081 cacgaggata aggcggtttc gttggcatcg ttcttcctta tttcacggga tgaacgttaa
   118141 gtataggcgc tctaaaatca acaattgatc gtctgtgcca gggcgctacg aatttcagaa
   118201 atcacctggc tgggttcgtt tgttgcgtcg atgataatat gcgcaacttc gcgatatagc
   118261 gcatcgcgtt cttccagcac ttcctgaact tcttcgctca gcggttttcc cgttaaggtt
   118321 ggccgtaaat cttcttccgg tgcagcttgc agtcggttaa ccaggactga tactggcgca
   118381 cacaaataaa ccacgatccc gttattttgc ataaagtgac gattaaattc cgtcagaata
   118441 atgccgccgc ctgtagcgat aacggtggat ggcgcagtta ccgcttccag cgccgccgtt
   118501 tctctggcgc gaaatcccgc ccactcttcc ctttcgacga tctccgcgac cgtcatattg
   118561 agctgtgatt gcaaccactg atcggtatcg acaaaccgac ggttaagcga atcggcaagg
   118621 gccattccga ccgttgtttt accacagccc cgaggcccga tcagaaaaag aggttgtgtc
   118681 atcgtgggtt ttccccaata ggtcgcaatg cggcgaaagc cggtgtcatg agaatagcga
   118741 tcataccatc aaactagtac aatttcgatt gtaaagaaaa aattccactt aaagtgaaaa
   118801 tctcaataca tcccttacta taccaataaa tattcaagaa tgaagtgtaa acaataaatt
   118861 acatttagcc acgactacgt tgcacttcca gccaccactt ctccagctcc gcggcaaagg
   118921 cctggcggtc acgttgtgaa aggctatctg gtccgccggt ctggatccca ctggcacgta
   118981 aggtatccat aaaatcgcgc atcgtcaggc gctcacgaat ggtcgctggc gtgtaacgtt
   119041 cgccgcgcgg attaagcgcc gctgcgcctt tctcgatggc ttcagcagcc aaaggtatat
   119101 ctgcggtgat caccaaatcg cccgcttcac actgccggac aatttcgtta tcggcaacgt
   119161 cgaaacctgc cgcgacgcgc agcgtacgaa taaatcgcga tggcggcacg cgtaaactct
   119221 ggtttgctac cagtaccagc ggcatctgca tacgttccgc cgcgcgatac aaaatctctt
   119281 taattacact gggacacgcg tcggcatcca cccaaattgt cataaagtca tcctttgttg
   119341 ggtaatcctc tattgtgtcg cgcttttgcc ttccggcata gttctgttta tgcttctgcc
   119401 agcgattatc aaaacaatga atttcacggc aggagtgagg caatggaaaa gaaaatcggt
   119461 tttattggct gcggcaatat gggaaaagcc attctcggcg gtctgattgc cagcggtcag
   119521 gtgcttccag ggcaaatctg ggtatacacc ccctccccgg ataaagtcgc cgccctgcat
   119581 gaccagttcg gcatcaacgc cgcagaatcg gcgcaagaag tggcgcaaat cgccgacatc
   119641 atttttgccg ccgttaaacc tggcatcatg attaaagtgc ttagcgaaat cacctccagc
   119701 ctgaataaag actctctggt cgtttctatt gctgcaggtg tcacgctcga ccagcttgcc
   119761 cgcgcgctgg gccatgaccg gaaaattatt cgcgccatgc cgaacactcc cgcgctggtt
   119821 aatgccggga tgacctccgt aacgccaaac gcgctggtaa ccccagaaga taccgctgat
   119881 gtgctgaata ttttccgctg ctttggcgaa gcggaagtaa ttgctgagcc gatgatccac
   119941 ccggtggtcg gtgtgagcgg ttcttcgcca gcctacgtat ttatgtttat cgaagcgatg
   120001 gccgacgccg ccgtgctggg cgggatgcca cgcgcccagg cgtataaatt tgccgctcag
   120061 gcggtaatgg gttccgcaaa aatggtgctg gaaacgggag aacatccggg ggcactgaaa
   120121 gatatggtct gctcaccggg aggcaccacc attgaagcgg tacgcgtact ggaagagaaa
   120181 ggcttccgtg ccgcagtgat cgaagcgatg acgaagtgta tggaaaaatc agaaaaactc
   120241 agcaaatcct gatgactttc gccggacgtc aggccgccac ttcggtgcgg ttacgtccgg
   120301 ctttctttgc tttgtaaagc gccaaatctg ccgatttcaa ccactcacga tagtgactca
   120361 tttgtgggtt cagcggcgca acccccacac taatccgtaa agttacctgt ggcgtattcg
   120421 gcaagcgtaa cgtgtttagc ccttcacgca cccgtaacat ggcggtaatg gcgctctcag
   120481 ctggcgtacc ggacatgatt actgcaaact catcgccgcc aaaccgacca atcacatcgc
   120541 taccgcgcag ggtaatttgt aactgtcggg taagcgccac aatcgcttca tcgcccacat
   120601 catgacccca ggtatcgttg atgctcttga aatggtcgat atcgataatc agtaacgttg
   120661 catcgcgatt atgccgccga cagttatcaa attcattgcg taacatagtt tcccaatgac
   120721 gtcggttata cacgcccgtc atgccgtcgc gggtactcat gacctgcaac ctgcgtttat
   120781 gttccgccag tttggttgcc gtctggtagc tgacccagcc aaacagcaga ggataaacga
   120841 caataatggg aagggagagc caccattcca gcggcgcact attgaacgac acggtaatgc
   120901 ccgtaagctc gagggtgaca aggcaggaaa ccaccatcaa caccagaccc gcgacaaaca
   120961 gacgggggcc gcctgccccc atcaaattca gacacataat catcaacata gcggtggaag
   121021 gcagcacgtt tacgcccatt acgcctaccc acattcccgc taatactgca tcggttttta
   121081 agttgtaaat ttcccggcta agcggatcga cggccctgct cgctatctgc caggctaaat
   121141 gcggccagac gaacgcccag ccgaccaaca ccagccacca ccagcccggc ggcgggtgcg
   121201 aaaccagcgt tgaagcaatc ggtaagaaca tgccagccag gccaaccgca cggggtagtc
   121261 tgacgcgacg ggcgaagcgc agcccggacc gctgatgttc gttttgagga gttaaaggag
   121321 gttcctcccc atgcgccgcc gcttttttga aaaagttttc atcattcatt atttttggga
   121381 acattcagaa acaattttcc caaattatag agacggggct aaaggcagaa gtatgaaatt
   121441 tcgggtgagc cactttcgta gctcacccgt tagcactatc aggtatcagg cggctttctt
   121501 gaggcaggca ctcataaact tattacgatc atcacctttc agagattgtt gcgttgcttg
   121561 attattacat tcgcgcatct tttgctgctg tggcgtcaaa cttttttcac caggcgcaga
   121621 cttgctgttc ttcaggcaat cactcatgta ggtcttacga gcatcccctt tcaacgcctg
   121681 cgccgtcgcc tgctgattac aggaggtcat acgctgttgt tgtggggtta aggttttctc
   121741 ggcagcgccg acggtggtta aaaaaaccag accaaaaagc aaggtaacca gtaatgttat
   121801 tttcatagca ccatccctct tcatgtttta accatgagcg tttgcgcccg tgatctgcca
   121861 ttaagtctgg ttgctaacag caaaaaaacc acccggcagc gaaaattcac tgccgggcgc
   121921 ggttttattt cagccccaga gcggctttca tggtgtagaa gagatcggtc tggtcggtca
   121981 gtccaacaac attggcggca tgcgggccat acgccgcaat acgcaactga ctgccggtat
   122041 gttcttgtga atcctcttca gagttcccgt aactcatcac catcactgcg ccatctttag
   122101 tatttagcgc ctgagtgagg cccggcgctt tggtatccgg cgcaacaacc tggctggcgt
   122161 gggcgtgatc agcggtgact atgaccagcg tgttaccctc ctttttagcg aattccagcg
   122221 cccgttgtac ggcttcatcg agatcgaccg tctcgccaat ttgcccacaa ggattcgcag
   122281 cgtgatcctg tttatcgatt gacgcacctt caacttgcag gaaaaatcct ttctcatttt
   122341 tactcaacaa ttcaatggct ttgtcggtca tctgtgccag ggttggtaca ctgtcattac
   122401 gttgcggatt aggcgtacag gtgactgcgg gcttatcgat attgccgtgg tacgttgctt
   122461 tcggccctag ccagcgcact ggcatattgc cgtcagcaaa caggccaagc aggggttttt
   122521 gctgattcgc ttccgtcacc gaattcagtg aggcagcatc gttcaccaac tgataaccac
   122581 gcgcctgtgc ctgttcacgc agcgtttttc cctgccattc accagcggtt gccgtttcag
   122641 caaaggtttt tgcgccgccg ccaagcgtaa cgtcggcacg agcgttaagc agctgttcgg
   122701 taatcgatcc ttttccgcct ttttccagag cgttacccgg acatttttca ctggtcgcgc
   122761 tcggaccgta gcatttgcgc gaagtcacat gtgccaccag cgcagcgggc gtggcatcct
   122821 gcaactctgc ggtagaaacg ttaccggtcg ccagacctgc ggcttttgcc atttccagaa
   122881 tcgttgggtg atctttttcg tgaatatcga cgcccagcgc gccgttatag gttttgacac
   122941 cggttgacca ggcggttgct gatgcagccg agtcggtgac gtagtccggt ttgccagttt
   123001 ttttattcag cgcatagtga gtgtattgcc cggtaagcgg taaggcatcg atacctttaa
   123061 aaaagccgcc cgcaccttcg gcataattac gtgcggcagt aatttccgaa tcccccatcc
   123121 catcgccaat cagcaaaata atattttttg caggtttatc gctaagagaa tcacgcagag
   123181 cggcggtatg atcacccgtt aagcggcgag caccgccggg tgcagtaata tcgccctgag
   123241 cagcccggtt ttccagaaca ggcatttctg gagtccgggc ttttgtcaca ggggtaaaca
   123301 gtaacgttaa gagtgccagt gcaatagtgc tttgtttcac tttattttct ccatgtacaa
   123361 atacattaaa aaataaaaac aaagcgacta taagtctcgg ccgtgacaac tttatgacag
   123421 ctgttgaaaa gattaacttt ttactgacga ggatgcttca ataacttctt tacgtaatcg
   123481 cgcagcagct ccgtatcgtc gtcaggaatg ctggcatcgg gctttacctc gtacagcgcc
   123541 ccctctacct gatcaatcaa ccgctgttgg tcattttgcg ccatattgcg aagcattgca
   123601 gtgacgataa tctccaaagc ttctacctgc gcacacagtt ctttcgactc ttcttctttt
   123661 tgggcaagct taaataacaa ctcagcaatg agatttttca tgtctgtatt tccttatcca
   123721 aagtatggag aagttaacat tatgtttcac aacttcatag tgtctggaag tattattttt
   123781 atgacaaagg aaatactttg cgcaaatatt ttttgtttga ttaccagcga aacgttt
//
LOCUS       DAZUDJ010000006       118708 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.006, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000006 DAZUDJ010000000
VERSION     DAZUDJ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 118708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118708
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.006"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..112
                     /locus_tag="ACHY1N_000604"
     CDS             <1..112
                     /locus_tag="ACHY1N_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309530.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HFS4042950.1"
                     /translation="AIPFEGERHNALDDARYQAKYVSVIWQKLIPSQADF"
     gene            174..443
                     /locus_tag="ACHY1N_000605"
     CDS             174..443
                     /locus_tag="ACHY1N_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFS4042951.1"
                     /translation="MSEQYLITLDEWKPKRFSLPITNTTLVKYGKLGYIVPRPQKIRG
                     RWLIDRRAVFVGPGETGIAPEIHTGDDDALKEILTHVTEATKKQH"
     gene            412..1530
                     /locus_tag="ACHY1N_000606"
     CDS             412..1530
                     /locus_tag="ACHY1N_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase Arm DNA-binding
                     domain-containing protein"
                     /protein_id="HFS4042952.1"
                     /translation="MSPRPRKNSTDVAGLYEKFDRRTGRVYYQYKNPVTGKFHGLGTD
                     KGKAEKIASTANQRIAAAEAEYFMRKIDESPSATKRRGIRLKAWVDRYLKIQDTRLKN
                     GDIAATTHKEKARMAAYLVSRLGNHPLKELEVRDFALILDEWLDKDMVSTARVNRGLW
                     VDIYKEAQHAGEVPPGWNPPEATRKPIPKVTRARLTLEDWQKIYNATPEKHFIRNAML
                     LAIVTGQRRDDICHMRFSDVWNEHLHITQGKTGMRLALPLTLRCDAIGITLKEVIDGC
                     RDRILSPYLIHSRHQKQPKPMSKDNLSDYFAKARDLAGITPPAGKTPPTFHEQRSLSE
                     RLYRAQGIDTKTLLGHKVQATTDRYNDTRGQEWVKLVV"
     gene            complement(1607..2074)
                     /locus_tag="ACHY1N_000607"
     CDS             complement(1607..2074)
                     /locus_tag="ACHY1N_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2335 domain-containing protein"
                     /protein_id="HFS4042953.1"
                     /translation="MPDQKESENTKLTCEEQKDNELVSRVIENPEVLNRVLDSPQVRA
                     IVCQHFQGPVPPPSMLKKYDQLVPGLANRLVELTEKEQAHRHKTVADSIDIARDGQTK
                     AFWLAILIILAATVFGVMGETVLAGTLVSIDLVALVTAFIVGKHYSKQEPDQD"
     gene            complement(2052..2255)
                     /locus_tag="ACHY1N_000608"
     CDS             complement(2052..2255)
                     /locus_tag="ACHY1N_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009433571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4042954.1"
                     /translation="MKRKSVALLQAIGSVIALSPTVVSANGMPANPVSALRQDAAAIR
                     GDFQKAMVSVNVEKLNNARSKRK"
     gene            2564..3358
                     /gene="potC"
                     /locus_tag="ACHY1N_000609"
     CDS             2564..3358
                     /gene="potC"
                     /locus_tag="ACHY1N_000609"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HFS4042955.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKI
                     YSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK"
     gene            3355..4401
                     /gene="potD"
                     /locus_tag="ACHY1N_000610"
     CDS             3355..4401
                     /gene="potD"
                     /locus_tag="ACHY1N_000610"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0019808 - polyamine binding [Evidence
                     IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HFS4042956.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHADDNNTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLSNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYK
                     GSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMIWNGSAFVARQAGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGEWQNDVGAAS
                     SIYEEYYQKLKAGR"
     gene            4459..4920
                     /locus_tag="ACHY1N_000611"
     CDS             4459..4920
                     /locus_tag="ACHY1N_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001460774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3592 domain-containing protein"
                     /protein_id="HFS4042957.1"
                     /translation="MSQDSKVLSRAFLGIGLILLVISAIIFYYHFTFTKSAVHTEGII
                     VDAVWYNNHSNDVDDNGSWYPVVAFRPTPDYTLIFNSNIGSDFYEDSEGDRVNVYYPP
                     GHPEQAEINNPWVNFFKWGFVGIAGIIFGSVGLIITLPSTKKSRRKRKSRP"
     gene            4917..5705
                     /gene="ycfZ"
                     /locus_tag="ACHY1N_000612"
     CDS             4917..5705
                     /gene="ycfZ"
                     /locus_tag="ACHY1N_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgcG family protein"
                     /protein_id="HFS4042958.1"
                     /translation="MKKFIILLSLLILLPLVATSKPLIPIMKTLFTDVTGTVPDAEEI
                     ARKAELFRQQTGIAPFIVILPDINNEASLRQNGKAMLAHASSSLSNVKGSVLLLFTTR
                     EPRLIMITNGQVESGLDDKHLGLLIENHTLAYLNADLWYQGINNALAVLQAQILKQPT
                     PPLTYYPHPGQQHENAPPGSTNTLGFIAWAATFILFSWIFCYTTRFIYALKFAVAMTI
                     ANMGYQALCLYIDNSFAITRISPLWAGLIGVCTFIAALLLTSKR"
     gene            complement(5844..6665)
                     /gene="cobB"
                     /locus_tag="ACHY1N_000613"
     CDS             complement(5844..6665)
                     /gene="cobB"
                     /locus_tag="ACHY1N_000613"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sir2 family NAD+-dependent deacetylase"
                     /protein_id="HFS4042959.1"
                     /translation="MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQP
                     EIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQ
                     VLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGL"
     gene            complement(6681..7592)
                     /gene="nagK"
                     /locus_tag="ACHY1N_000614"
     CDS             complement(6681..7592)
                     /gene="nagK"
                     /locus_tag="ACHY1N_000614"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045127 - N-acetylglucosamine kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HFS4042960.1"
                     /translation="MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVC
                     ELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRL
                     PVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQG
                     DEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLADRLPRHLLPV
                     ARVPRIERARHGDAGGMRGAAFLHLTD"
     gene            complement(7621..8865)
                     /gene="lolE"
                     /locus_tag="ACHY1N_000615"
     CDS             complement(7621..8865)
                     /gene="lolE"
                     /locus_tag="ACHY1N_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HFS4042961.1"
                     /translation="MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDHVQKVPGIAAAAPYINFTG
                     LVESGANLRAIQVKGVNPQQEQRLSALPSFVQGDAWRNFKAGEQQIIIGKGVADALKV
                     KQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMG
                     SSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     VLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCG
                     VIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            complement(8865..9566)
                     /gene="lolD"
                     /locus_tag="ACHY1N_000616"
     CDS             complement(8865..9566)
                     /gene="lolD"
                     /locus_tag="ACHY1N_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309522.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HFS4042962.1"
                     /translation="MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEINSRALEMLKAVGLEHRANHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            complement(9559..10758)
                     /gene="lolC"
                     /locus_tag="ACHY1N_000617"
     CDS             complement(9559..10758)
                     /gene="lolC"
                     /locus_tag="ACHY1N_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HFS4042963.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGD
                     QIRMMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGNEMLVNIEDASRLMRYPAGN
                     ITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGA
                     LLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            11020..12093
                     /gene="ycfT"
                     /locus_tag="ACHY1N_000618"
     CDS             11020..12093
                     /gene="ycfT"
                     /locus_tag="ACHY1N_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFS4042964.1"
                     /translation="MKQKELWINQIKGLCICLVVIYHSVITFYPHLTTFQHPLSEVLS
                     KCWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVPWGNCLDKRIWNIFWVLALWGVVQW
                     LALSALNQWLAPERDLSNASNAAYADSTGEFLHGMITASTSLWYLYALIVYFVVCKIF
                     SRLALPLFALFVLLSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATIMTCVKEVPLR
                     RHLLMASLLTVLAVGAWLFTISLLLSLVSIVVIMKLFYQYEQRFGMRSTSLLNVIGSN
                     TIAIYTTHRILVEIFSLTLLAQMNAARWSPQVELTLLLVYPFVSLFICTVAGLLVRKL
                     SQRAFSDLLFTPPSLPAAVSYSR"
     gene            12221..15667
                     /gene="mfd"
                     /locus_tag="ACHY1N_000619"
     CDS             12221..15667
                     /gene="mfd"
                     /locus_tag="ACHY1N_000619"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFS4042965.1"
                     /translation="MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHAGPVVL
                     IAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDSFSPHQDIISSRLSTLYQLPTMQ
                     RGVLIVPVNTLMQRVCPHSFLHGHALVMKKGQRLSRDALRTQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEATNLLPAHEFP
                     TDKAAIELFRSQWRDIFEVKRDPEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLLVNTGDLETSAERFQTDTLARFENRGVDPMRPLLPPQSLWLRVDELFSELKNW
                     PRVQLKTEHLPTKAANANLGFQKLPDLAVQAQQKAPLDALRKFLETFDGPVVFSVESE
                     GRREALGELLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDKVRNLALICESDLL
                     GERVARRRQDSRRTINPDTLIRNLAELHIGQPVVHLEHGVGRYAGMTTLEAGGITGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     ISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLGLLIVDEEHRFGVRHKE
                     RIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSLVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKTENELEEIKVELIDRFGLLPDPARTLLDVARLRQQAQKLGIRKLEGNEKGGVIE
                     FAEKNHVNPAWLIGLLQKQPQHYRLDGPTRLKFIQDLSERKTRIEWVRQFMRELEENA
                     IA"
     gene            15811..16773
                     /gene="ldtC"
                     /locus_tag="ACHY1N_000620"
     CDS             15811..16773
                     /gene="ldtC"
                     /locus_tag="ACHY1N_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtC"
                     /protein_id="HFS4042966.1"
                     /translation="MMIKTRFSRWLTFFTFAAAVALALPAKANTWPLPPAGSRLVGEN
                     KFHVVENDGGSLEAIAKKYNVGFLALLQANPGVDPYVPRAGSVLTIPLQTLLPDAPRE
                     GIVINIAELRLYYYPPGKNSVTVYPIGIGQLGGDTLTPTMVTTVSDKRANPTWTPTAN
                     IRARYKAQGIELPAVVPAGPDNPMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCI
                     RLRDDDIKTLFSQVTPGTKVNIINTPIKVSAEPNGARLVEVHQPLSEKIDDDPQLLPI
                     TLNSAMQSFKDAAQTDAEVMQHVMDVRSGMPVDVRRHQVSPQTL"
     gene            complement(16856..17113)
                     /gene="bhsA"
                     /locus_tag="ACHY1N_000621"
                     /gene_synonym="ycfR"
     CDS             complement(16856..17113)
                     /gene="bhsA"
                     /locus_tag="ACHY1N_000621"
                     /gene_synonym="ycfR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple stress resistance protein BhsA"
                     /protein_id="HFS4042967.1"
                     /translation="MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAG
                     TNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGTAVIYK"
     gene            17354..17986
                     /gene="comR"
                     /locus_tag="ACHY1N_000622"
     CDS             17354..17986
                     /gene="comR"
                     /locus_tag="ACHY1N_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415629.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HFS4042968.1"
                     /translation="MATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFA
                     AIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGE
                     IPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK"
     gene            complement(18048..18587)
                     /gene="ycfJ"
                     /locus_tag="ACHY1N_000623"
     CDS             complement(18048..18587)
                     /gene="ycfJ"
                     /locus_tag="ACHY1N_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HFS4042969.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRITGSVLGAVAGGVIGHQFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRD
                     PGTQIPLDSNGQLILNNKV"
     gene            complement(18797..20101)
                     /gene="ndh"
                     /locus_tag="ACHY1N_000624"
     CDS             complement(18797..20101)
                     /gene="ndh"
                     /locus_tag="ACHY1N_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone dehydrogenase"
                     /protein_id="HFS4042970.1"
                     /translation="MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHS
                     HLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDE
                     KGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLK
                     YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGE
                     RILPALPPRISAAAHNELTKLGVRVLTQTMVTSADKGGLHTKDGEYIEADLMVWAAGI
                     KAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAA
                     HQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRI
                     ARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH"
     gene            complement(20501..21043)
                     /gene="ycfP"
                     /locus_tag="ACHY1N_000625"
     CDS             complement(20501..21043)
                     /gene="ycfP"
                     /locus_tag="ACHY1N_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase YcfP"
                     /protein_id="HFS4042971.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPNENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
     gene            complement(21066..22091)
                     /gene="nagZ"
                     /locus_tag="ACHY1N_000626"
     CDS             complement(21066..22091)
                     /gene="nagZ"
                     /locus_tag="ACHY1N_000626"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HFS4042972.1"
                     /translation="MGPVMLDVEGYELDAEEREILAHPLVGGLILFKRNYHDPAQLRE
                     LVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSD
                     VDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISTRLNQLHERW
                     QEEKAGH"
     gene            complement(22102..22926)
                     /gene="thiK"
                     /locus_tag="ACHY1N_000627"
     CDS             complement(22102..22926)
                     /gene="thiK"
                     /locus_tag="ACHY1N_000627"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019165 - thiamine kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HFS4042973.1"
                     /translation="MPFRSNNPIMRDELLSRFFPQFHPVTTFHSGLSGGSFLIEHQGQ
                     RFVVRQPHDPDAPRFAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGEVKTYLPD
                     TNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRRLKRLRKAREPRP
                     LRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTDQHRQLVNDYA
                     TRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ"
     gene            complement(22907..23548)
                     /gene="lpoB"
                     /locus_tag="ACHY1N_000628"
     CDS             complement(22907..23548)
                     /gene="lpoB"
                     /locus_tag="ACHY1N_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HFS4042974.1"
                     /translation="MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPAEPQQ
                     PVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRHYDWNGAMQPMVSKMLGADGVTAGSV
                     LLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGT
                     RSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ"
     gene            complement(23562..23939)
                     /gene="ycfL"
                     /locus_tag="ACHY1N_000629"
     CDS             complement(23562..23939)
                     /gene="ycfL"
                     /locus_tag="ACHY1N_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HFS4042975.1"
                     /translation="MRKGCFGLVSLALLLLVGCRSHPEIPVNDEQSLVMESSLLAAGI
                     SAEKPVLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVSIPAH
                     SAVTLYGSANFLGAHKVRLYLYL"
     gene            complement(23942..24301)
                     /gene="hinT"
                     /locus_tag="ACHY1N_000630"
     CDS             complement(23942..24301)
                     /gene="hinT"
                     /locus_tag="ACHY1N_000630"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415621.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HFS4042976.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIP
                     NILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            24635..26824
                     /gene="fhuE"
                     /locus_tag="ACHY1N_000631"
     CDS             24635..26824
                     /gene="fhuE"
                     /locus_tag="ACHY1N_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015344 - siderophore uptake transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0038023 - signaling receptor activity
                     [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
                     /protein_id="HFS4042977.1"
                     /translation="MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFAAPATEETV
                     IVEGSATAPDDGENDYSVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVM
                     ENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
                     VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDG
                     KIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTWG
                     GLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQRFADTWQATLNATHSEVE
                     FDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYEL
                     FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTT
                     HMKSLYAATRVTLADPLHLILGARYTNWRVDTLTYSMEKNHTTPYAGLVFDINDNWST
                     YASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQ
                     STGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVN
                     PNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLF
                     TRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRNFSITGTYQF"
     gene            complement(26884..28317)
                     /gene="ptsG"
                     /locus_tag="ACHY1N_000632"
     CDS             complement(26884..28317)
                     /gene="ptsG"
                     /locus_tag="ACHY1N_000632"
                     /EC_number="2.7.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005355 - glucose transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:1904659 - glucose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HFS4042978.1"
                     /translation="MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
                     AIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATED
                     AKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNH"
     gene            complement(28612..29409)
                     /gene="ycfH"
                     /locus_tag="ACHY1N_000633"
     CDS             complement(28612..29409)
                     /gene="ycfH"
                     /locus_tag="ACHY1N_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFS4042979.1"
                     /translation="MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYT
                     PETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR"
     gene            complement(29420..30424)
                     /gene="holB"
                     /locus_tag="ACHY1N_000634"
     CDS             complement(29420..30424)
                     /gene="holB"
                     /locus_tag="ACHY1N_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFS4042980.1"
                     /translation="MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYAL
                     SRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNALGIDAVREVTEKLNE
                     HARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR
                     LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQ
                     ALAYSVPSGDWYSLLAALNHEQAPARLHWLATLLMDALKRHHGAAQVTNVDVPGLVAE
                     LANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIEHYLQPGVVLPVPHL
                     "
     gene            complement(30421..31062)
                     /gene="tmk"
                     /locus_tag="ACHY1N_000635"
     CDS             complement(30421..31062)
                     /gene="tmk"
                     /locus_tag="ACHY1N_000635"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFS4042981.1"
                     /translation="MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGT
                     QLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHD
                     LSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIE
                     QESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA"
     gene            complement(31052..32074)
                     /gene="yceG"
                     /locus_tag="ACHY1N_000636"
     CDS             complement(31052..32074)
                     /gene="yceG"
                     /locus_tag="ACHY1N_000636"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HFS4042982.1"
                     /translation="MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTL
                     KPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLL
                     ESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGW
                     FWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKE
                     TAVASERDQVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTI
                     TGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVL
                     KEKNAQ"
     gene            complement(32077..32886)
                     /gene="pabC"
                     /locus_tag="ACHY1N_000637"
     CDS             complement(32077..32886)
                     /gene="pabC"
                     /locus_tag="ACHY1N_000637"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008696 - 4-amino-4-deoxychorismate lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0046656 - folic acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HFS4042983.1"
                     /translation="MFLINGYKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQ
                     RLQDACQRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATR
                     ILSVTAYPAHYDRLRNEGMTLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNAD
                     EALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVE
                     VQASLEEALQADEMVICNALMPVMPVRACGDVSFSSATLYEYLAPLCERPN"
     gene            complement(33006..34247)
                     /gene="fabF"
                     /locus_tag="ACHY1N_000638"
     CDS             complement(33006..34247)
                     /gene="fabF"
                     /locus_tag="ACHY1N_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFS4042984.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIG
                     AAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPEN
                     GAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSS
                     TKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGME
                     YTLCNSFGFGGTNGSLIFKKI"
     gene            complement(34335..34571)
                     /gene="acpP"
                     /locus_tag="ACHY1N_000639"
     CDS             complement(34335..34571)
                     /gene="acpP"
                     /locus_tag="ACHY1N_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFS4042985.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            complement(34782..35516)
                     /gene="fabG"
                     /locus_tag="ACHY1N_000640"
     CDS             complement(34782..35516)
                     /gene="fabG"
                     /locus_tag="ACHY1N_000640"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HFS4042986.1"
                     /translation="MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQA
                     ISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANA
                     VAFLASDEAAYITGETLHVNGGMYMV"
     gene            complement(35529..36458)
                     /gene="fabD"
                     /locus_tag="ACHY1N_000641"
     CDS             complement(35529..36458)
                     /gene="fabD"
                     /locus_tag="ACHY1N_000641"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFS4042987.1"
                     /translation="MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCA
                     GVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAK
                     ITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPSAMAAALEL"
     gene            complement(36474..37427)
                     /gene="fabH"
                     /locus_tag="ACHY1N_000642"
     CDS             complement(36474..37427)
                     /gene="fabH"
                     /locus_tag="ACHY1N_000642"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFS4042988.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHI
                     AAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDG
                     AGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVT
                     ELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF"
     gene            complement(37495..38565)
                     /gene="plsX"
                     /locus_tag="ACHY1N_000643"
     CDS             complement(37495..38565)
                     /gene="plsX"
                     /locus_tag="ACHY1N_000643"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFS4042989.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDA
                     ITPLLAKADFEQRSRLQIIPAQSVIASDVRPSQAIRASRGSSMRVALELVKEGRAQAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFELLDGGKSGTLR"
     gene            complement(38646..38819)
                     /gene="rpmF"
                     /locus_tag="ACHY1N_000644"
     CDS             complement(38646..38819)
                     /gene="rpmF"
                     /locus_tag="ACHY1N_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFS4042990.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            complement(38871..39392)
                     /gene="yceD"
                     /locus_tag="ACHY1N_000645"
     CDS             complement(38871..39392)
                     /gene="yceD"
                     /locus_tag="ACHY1N_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HFS4042991.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLNGDAKVTVTLECQRCGKPFTHQVYTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLAMVEDEIILALPVVPVHDSEHCEVSEADMVFGELPEEAQK
                     PNPFAVLASLKRK"
     gene            39591..40175
                     /gene="yceF"
                     /locus_tag="ACHY1N_000646"
     CDS             39591..40175
                     /gene="yceF"
                     /locus_tag="ACHY1N_000646"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-methyl-GTP pyrophosphatase"
                     /protein_id="HFS4042992.1"
                     /translation="MPKLILASTSPWRRALLEKLQISFECAAPEVDETPRSDESPRQL
                     VLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTF
                     YTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITL
                     FERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG"
     gene            complement(40287..41246)
                     /gene="rluC"
                     /locus_tag="ACHY1N_000647"
     CDS             complement(40287..41246)
                     /gene="rluC"
                     /locus_tag="ACHY1N_000647"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HFS4042993.1"
                     /translation="MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDRQLTEAGTG
                     LNRLFLHAAALKFTHPGTGEVMRIEAPMDEGLKRCLQKLRNAR"
     gene            41819..45004
                     /gene="rne"
                     /locus_tag="ACHY1N_000648"
     CDS             41819..45004
                     /gene="rne"
                     /locus_tag="ACHY1N_000648"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008995 - ribonuclease E activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HFS4042994.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAAPATPATPA
                     QPGLLSRFFGALKALFSGSEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRD
                     TRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTTDEQQAPRRERSRR
                     RNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAV
                     VAPVVEETAAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRS
                     RRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQV
                     EEQREQEEVHVQPMVTEVPVAAAIEPVVSAPVVEEVAGVVEAPVQVAEPQPEVVETTH
                     PEVIAAAVTEQPQVITESDVVVAQEVAEQAEPVVEPQEETADIEEVVETAEVVVAEPE
                     VVAQPAAPVVAEVAAEVETVAAVEPEVTVEHNHATAPMTRAPAPEYVPEAPRHSDWQR
                     PTFAFEGKGAAGGHTATHHASAAPARPQPVE"
     gene            complement(45200..46153)
                     /gene="flgL"
                     /locus_tag="ACHY1N_000649"
     CDS             complement(45200..46153)
                     /gene="flgL"
                     /locus_tag="ACHY1N_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HFS4042995.1"
                     /translation="MRFSTQMMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPI
                     AASQAVVLSQAQAQNSQYTLARTFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTL
                     SDDDRASLATDIQGLRDQLLNLANTTDGNGRYIFAGYKTETAPFSEEKGKYVGGAESI
                     KQQVDASRSMVIGHTGDKIFDSITSNAVAEPDGSASETNLFAMLDSAIAALKTPVADS
                     EADKETAAAALDKTNRGLKNSLNNVLTVRAELGTQLNELESLDSLGSDRALGQTQQMS
                     DLVDVDWNATISSYIMQQTALQASYKAFTDMQGLSLFQLNK"
     gene            complement(46165..47808)
                     /gene="flgK"
                     /locus_tag="ACHY1N_000650"
     CDS             complement(46165..47808)
                     /gene="flgK"
                     /locus_tag="ACHY1N_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HFS4042996.1"
                     /translation="MSSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQA
                     NSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTS
                     TSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNI
                     AIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVS
                     VQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLN
                     TGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNSQHKAGFDANGDAGEDFFTIGKPA
                     VLQNTKNKGDVAIGATVTDASVVLATDYKISFDNNQWQVTRLASNTTFTATPDANGKV
                     AFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQ
                     ALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSTTQGNVVTQLSNQQQSIS
                     GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR"
     gene            complement(47874..48815)
                     /gene="flgJ"
                     /locus_tag="ACHY1N_000651"
     CDS             complement(47874..48815)
                     /gene="flgJ"
                     /locus_tag="ACHY1N_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HFS4042997.1"
                     /translation="MISDSKLLASAAWDAQSLNELKAKVGEDPAANIRPVARQVEGMF
                     VQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQ
                     PLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPA
                     QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITT
                     TEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAG
                     YATDPHYARKLTNMIQQMKSISDKVSKTYSMNIDNLF"
     gene            complement(48815..49912)
                     /gene="flgI"
                     /locus_tag="ACHY1N_000652"
     CDS             complement(48815..49912)
                     /gene="flgI"
                     /locus_tag="ACHY1N_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415598.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HFS4042998.1"
                     /translation="MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDA
                     RTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            complement(49924..50622)
                     /gene="flgH"
                     /locus_tag="ACHY1N_000653"
     CDS             complement(49924..50622)
                     /gene="flgH"
                     /locus_tag="ACHY1N_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009427 - bacterial-type flagellum basal
                     body, distal rod, L ring [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HFS4042999.1"
                     /translation="MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPT
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT
                     NFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            complement(50675..51457)
                     /gene="flgG"
                     /locus_tag="ACHY1N_000654"
     CDS             complement(50675..51457)
                     /gene="flgG"
                     /locus_tag="ACHY1N_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009426 - bacterial-type flagellum basal
                     body, distal rod [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HFS4043000.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            complement(51595..52350)
                     /gene="flgF"
                     /locus_tag="ACHY1N_000655"
     CDS             complement(51595..52350)
                     /gene="flgF"
                     /locus_tag="ACHY1N_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgF"
                     /protein_id="HFS4043001.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVEGLSLPTRTLVTASTPGADMTPGKMDYTSRPLDVALQQDGWLAVQSADGSEGYTRN
                     GSIQVDPTGQLTIQGHPVIGEAGPIAVPEGAEITIAADGTISALNPGDPANTVAPVGR
                     LKLVKATGSEVQRGDDGIFRLSAESQATRGPILQADPTLRVMSGVLEGSNVNAVAAMS
                     DMIASARRFEMQMKVISSVDDNAGRANQLLSMS"
     gene            complement(52370..53575)
                     /gene="flgE"
                     /locus_tag="ACHY1N_000656"
     CDS             complement(52370..53575)
                     /gene="flgE"
                     /locus_tag="ACHY1N_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HFS4043002.1"
                     /translation="MAFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGLQLTGYPATGTPPTIQQGANPTNISIPNTLMAAKTTTTASMQINLNS
                     SDPLPTVTPFSASNADSYNKKGSVTVFDSQGNAHDMSVYFVKTGDNNWQVYTQDSSDP
                     TGTAEPAMKLVFNANGVLTSNPTENITTGAINGADPATFSLSFLNSMQQNTGANNIVA
                     TTQNGYKPGDLVSYQINDDGTVVGNYSNEQTQLLGQIVLANFANNEGLASEGDNVWSA
                     TQSSGVALLGTAGTGNFGTLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQ
                     ILNTLVNLR"
     gene            complement(53600..54295)
                     /gene="flgD"
                     /locus_tag="ACHY1N_000657"
     CDS             complement(53600..54295)
                     /gene="flgD"
                     /locus_tag="ACHY1N_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HFS4043003.1"
                     /translation="MSIAVTTTDPTNTGVSTTSSSSLTGSNAADLQSSFLTLLVAQLK
                     NQDPTNPMENNELTSQLAQISTVSGIEKLNTTLGSISGQIDNSQSLQASNLIGHGVMI
                     HGTTVLAGTGSEEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVH
                     SFTWDGTLTDGSTAPNGSYNVAISASNGGTQLVAQPLQFALVQGVIRGNSGNTLDLGT
                     YGTTTLDEVRQII"
     gene            complement(54307..54711)
                     /gene="flgC"
                     /locus_tag="ACHY1N_000658"
     CDS             complement(54307..54711)
                     /gene="flgC"
                     /locus_tag="ACHY1N_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030694 - bacterial-type flagellum basal
                     body, rod [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HFS4043004.1"
                     /translation="MALLNIFDIAGSALTAQSQRLNVAASNLANADSVTGPDGQPYRA
                     KQVVFQVNAAPGAATGGVKVADVIESQAPDKLVYEPGNPLADAKGYVKMPNVDVVGEM
                     VNTMSASRSYQANVEVLNTVKSMMLKTLTLGQ"
     gene            complement(54715..55131)
                     /gene="flgB"
                     /locus_tag="ACHY1N_000659"
     CDS             complement(54715..55131)
                     /gene="flgB"
                     /locus_tag="ACHY1N_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030694 - bacterial-type flagellum basal
                     body, rod [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HFS4043005.1"
                     /translation="MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDID
                     FASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPTAELQYRIPDQPSLDGNTVDM
                     DRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN"
     gene            55286..55945
                     /gene="flgA"
                     /locus_tag="ACHY1N_000660"
     CDS             55286..55945
                     /gene="flgA"
                     /locus_tag="ACHY1N_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009428 - bacterial-type flagellum basal
                     body, distal rod, P ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation chaperone
                     FlgA"
                     /protein_id="HFS4043006.1"
                     /translation="MLTIKRSVAIIAILFSPLSTASNLTSQLHNFFSAQLAGVSDEVR
                     VSIRTAPNLLPPCEQPLLSMSNNSRLWGNVNVLARCGNDKRYLQVNVQATGNYVVAAM
                     PIVRGGKLEAGNVKLKRGRLDTLPPRTVLDINQLVDAISLRDLSPDQPIQLTQFRQAW
                     RVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMVSGQVVSGVVDADGNILIN
                     L"
     gene            56021..56314
                     /gene="flgM"
                     /locus_tag="ACHY1N_000661"
     CDS             56021..56314
                     /gene="flgM"
                     /locus_tag="ACHY1N_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HFS4043007.1"
                     /translation="MSIDRTSPLKPVSTVQPRETTDAPVTNSRAAKTTASTSTSVTLS
                     DAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN"
     gene            56319..56735
                     /gene="flgN"
                     /locus_tag="ACHY1N_000662"
     CDS             56319..56735
                     /gene="flgN"
                     /locus_tag="ACHY1N_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HFS4043008.1"
                     /translation="MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITE
                     QKSSLLATLDYLEQLRKKEPNTANSVDISQRWQEITVKTQQLRQMNQHNGWLLEGQIE
                     RNQQALEMLKPHQEPTLYGANGQTSTIHRGGKKISI"
     gene            complement(56775..58310)
                     /gene="murJ"
                     /locus_tag="ACHY1N_000663"
     CDS             complement(56775..58310)
                     /gene="murJ"
                     /locus_tag="ACHY1N_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HFS4043009.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPALLNISMIGFALFAAPYFNPPVLALAWAVTVGGILQLVYQLPHLKKIGMLVLPR
                     INFHDAGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTV
                     SLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     LTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVV
                     AVLVMSGVLLGMLHIMPEWSLGTMPWRLLRLMAVVLAGIAAYFAALAVLGFKVKEFAR
                     RTV"
     gene            complement(58420..59343)
                     /gene="yceM"
                     /locus_tag="ACHY1N_000664"
     CDS             complement(58420..59343)
                     /gene="yceM"
                     /locus_tag="ACHY1N_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4043010.1"
                     /translation="MKKLRIGVVGLGGIAQKAWLPVLAAASDWTLQGAWSPTRAKALP
                     ICESWRIPYADSLSSLAASCDAVFVHSSTASHFDVVSTLLNAGVHVCVDKPLAENLRD
                     AERLVELAARKKLTLMVGFNRRFAPLYGELKTQLATAASLRMDKHRSNSVGPHDLYFT
                     LLDDYLHVVDTALWLSGGKASLDGGTLLTNDAGEMLFAEHHFSAGPLQITTCMHRRAG
                     SQRETVQAVTDGALIDITDMREWREERGQGVVHKPIPGWQSTLEQRGFVGCARHFIEC
                     VQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE"
     gene            complement(59345..59992)
                     /gene="yceH"
                     /locus_tag="ACHY1N_000665"
     CDS             complement(59345..59992)
                     /gene="yceH"
                     /locus_tag="ACHY1N_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HFS4043011.1"
                     /translation="MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     ITTLLLRGAQTPGELRSCAARMYEFSDMAEVESTLEQLANREDGPFVVRLARELGKRE
                     SRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD"
     gene            complement(60003..60587)
                     /gene="rimJ"
                     /locus_tag="ACHY1N_000666"
     CDS             complement(60003..60587)
                     /gene="rimJ"
                     /locus_tag="ACHY1N_000666"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HFS4043012.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSF
                     HACYLGYSIGQKWQGKGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR"
     gene            60823..62031
                     /gene="mdtH"
                     /locus_tag="ACHY1N_000667"
     CDS             60823..62031
                     /gene="mdtH"
                     /locus_tag="ACHY1N_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415583.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HFS4043013.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVHTPVREGMTRVMRDKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHR
                     LMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSY
                     MGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKR
                     AARRLLERDA"
     gene            62095..62742
                     /gene="grxB"
                     /locus_tag="ACHY1N_000668"
     CDS             62095..62742
                     /gene="grxB"
                     /locus_tag="ACHY1N_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HFS4043014.1"
                     /translation="MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVG
                     QKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLL
                     PRFAKSAFDEFSTPAARKYFVDKKEASAGNLADLLAHSDGLIKNISDDLRALDKLIVK
                     PNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI"
     gene            62876..63436
                     /gene="yceB"
                     /locus_tag="ACHY1N_000669"
     CDS             62876..63436
                     /gene="yceB"
                     /locus_tag="ACHY1N_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFS4043015.1"
                     /translation="MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSK
                     DIGLPGVADAHIVLTNLTSQIGREEPNKVTLTGDANLDMNSLFGSQKATMKLKLKALP
                     VFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGS
                     QGEAMAKKLAKGIEVKPGEIVIPFTD"
     gene            63542..64588
                     /gene="pyrC"
                     /locus_tag="ACHY1N_000670"
     CDS             63542..64588
                     /gene="pyrC"
                     /locus_tag="ACHY1N_000670"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_process: GO:0019856 - pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFS4043016.1"
                     /translation="MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLAPPVTTVEAAVAYRQRILDAVPAGHNFTPLMTCYLTDSLDPNELERGFNEGVFTAA
                     KLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIES
                     VMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRP
                     HLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTAL
                     GSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLV
                     PFLAGETVRWSVKQ"
     gene            64662..64907
                     /gene="dinI"
                     /locus_tag="ACHY1N_000671"
     CDS             64662..64907
                     /gene="dinI"
                     /locus_tag="ACHY1N_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein I"
                     /protein_id="HFS4043017.1"
                     /translation="MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRY
                     AAANNLSVIGATKEDKQRISEILQETWESADDWFVSE"
     gene            65197..65451
                     /gene="bssS"
                     /locus_tag="ACHY1N_000672"
     CDS             65197..65451
                     /gene="bssS"
                     /locus_tag="ACHY1N_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309465.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HFS4043018.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDFPVNEYRRH"
     gene            65566..66684
                     /gene="solA"
                     /locus_tag="ACHY1N_000673"
     CDS             65566..66684
                     /gene="solA"
                     /locus_tag="ACHY1N_000673"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050131 - N-methyl-L-amino-acid oxidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HFS4043019.1"
                     /translation="MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHH
                     GDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEDDPIFVRSGVINLGPADSAFLAN
                     VAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAK
                     EAGCAQLFNCPVTAIRHDDDGVTIETVDGEYQAKKAIVCAGTWVKDLLPELPVQPVRK
                     VFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERV
                     PFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITG
                     LSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ"
     gene            66732..66845
                     /locus_tag="ACHY1N_000674"
     CDS             66732..66845
                     /locus_tag="ACHY1N_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceO family protein"
                     /protein_id="HFS4043020.1"
                     /translation="MRRLLHYLINNIREHLMLYLFLWGLLAIMDLIYVFYF"
     gene            67106..67672
                     /gene="yceJ"
                     /locus_tag="ACHY1N_000675"
     CDS             67106..67672
                     /gene="yceJ"
                     /locus_tag="ACHY1N_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HFS4043021.1"
                     /translation="MSFTNTPERYGVISAAFHWLSAIIVYGMFALGLWMVTLSYYDGW
                     YHKAPELHKSIGILLMMGLVIRVLWRVISPPPGPLPSYSPMTRLAAKAGHLALYLLLF
                     AIGISGYLISTADGKPISVFGWFDVPATLADAGAQADFAGALHFWLAWSVVVLSVMHG
                     FMALKHHFIDKDDTLKRMLGKSSSDYGV"
     gene            67676..68251
                     /gene="yceI"
                     /locus_tag="ACHY1N_000676"
     CDS             67676..68251
                     /gene="yceI"
                     /locus_tag="ACHY1N_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HFS4043022.1"
                     /translation="MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKY
                     PQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGK
                     IKLKDFNIKTDLGPASQEVDLIISVEGVQQK"
     gene            complement(68293..69345)
                     /gene="trhO"
                     /locus_tag="ACHY1N_000677"
     CDS             complement(68293..69345)
                     /gene="trhO"
                     /locus_tag="ACHY1N_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706977.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFS4043023.1"
                     /translation="MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDA
                     LYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDD
                     GKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDS
                     HTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNK
                     SRGRLNTTLGIPDPTE"
     gene            69570..70490
                     /gene="lpxL"
                     /locus_tag="ACHY1N_000678"
     CDS             69570..70490
                     /gene="lpxL"
                     /locus_tag="ACHY1N_000678"
                     /EC_number="2.3.1.241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) lauroyltransferase"
                     /protein_id="HFS4043024.1"
                     /translation="MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGL
                     GKLALRFMKRRAKIVHRNLELCFPEMSEQERRKMVVKNFESVGMGLMETGMAWFWPDR
                     RIARWTEVIGMEHIRDVQAQKRGILLVGIHFLTLELGARQFGMQEPGIGVYRPNDNPL
                     IDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGEVVWYAPDHDYGPRSSVFVPLFAVEQ
                     AATTTGTWMLARMSGACLVPFVPRRKPDGKGYQLIMLPPECSPPLDDAETTAAWMNKV
                     VEKCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            70662..71888
                     /gene="mdtG"
                     /locus_tag="ACHY1N_000679"
     CDS             70662..71888
                     /gene="mdtG"
                     /locus_tag="ACHY1N_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HFS4043025.1"
                     /translation="MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQL
                     GVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMG
                     LAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPM
                     AGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNP
                     KLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAP
                     RLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQT
                     LLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAV
                     YSWNSLRRRRIPQVSN"
     gene            71971..72345
                     /gene="msyB"
                     /locus_tag="ACHY1N_000680"
     CDS             71971..72345
                     /gene="msyB"
                     /locus_tag="ACHY1N_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309456.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HFS4043026.1"
                     /translation="MTMYATLEEAIDAAREEFLADNPGIDAEDANVQQFNAQKYVLQD
                     GDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDYDEIEIRQEWQEENTLHEWDEGE
                     FQLEPPLDTEEGRAAADEWDER"
     gene            complement(72346..72573)
                     /gene="yceK"
                     /locus_tag="ACHY1N_000681"
     CDS             complement(72346..72573)
                     /gene="yceK"
                     /locus_tag="ACHY1N_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HFS4043027.1"
                     /translation="MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDS
                     AWRYVTILDLPFSLVFDTLLLPIDIHHGPYE"
     gene            complement(72746..75289)
                     /gene="mdoH"
                     /locus_tag="ACHY1N_000682"
     CDS             complement(72746..75289)
                     /gene="mdoH"
                     /locus_tag="ACHY1N_000682"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HFS4043028.1"
                     /translation="MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWARED
                     DSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDLWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAK
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRR
                     WGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHP
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQ
                     RSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ"
     gene            complement(75282..76817)
                     /gene="mdoG"
                     /locus_tag="ACHY1N_000683"
     CDS             complement(75282..76817)
                     /gene="mdoG"
                     /locus_tag="ACHY1N_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HFS4043029.1"
                     /translation="MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPK
                     SNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATA
                     VKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAY
                     KFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPS
                     AWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDED
                     KLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTS
                     IGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            77211..78368
                     /gene="mdoC"
                     /locus_tag="ACHY1N_000684"
     CDS             77211..78368
                     /gene="mdoC"
                     /locus_tag="ACHY1N_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706958.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HFS4043030.1"
                     /translation="MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEP
                     SLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLL
                     TLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
                     RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTL
                     FYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETES
                     VITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     TSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR"
     gene            complement(78376..79857)
                     /gene="clsC"
                     /locus_tag="ACHY1N_000685"
     CDS             complement(78376..79857)
                     /gene="clsC"
                     /locus_tag="ACHY1N_000685"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsC"
                     /protein_id="HFS4043031.1"
                     /translation="MMKKTPTSTKDSLPNKEMNDLPRLASAVLPLCSQHPGQCGLFPL
                     EKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDDN
                     NTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVV
                     TLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDV
                     PEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTLPLIWAKTRLLSDDPAK
                     GEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTN
                     SLAANDVAVVHGGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKT
                     FSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQYDAAWQLRLDR
                     WGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL"
     gene            complement(79799..80332)
                     /gene="ymdB"
                     /locus_tag="ACHY1N_000686"
     CDS             complement(79799..80332)
                     /gene="ymdB"
                     /locus_tag="ACHY1N_000686"
                     /EC_number="3.1.1.106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HFS4043032.1"
                     /translation="MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGP
                     ALLDACLKVRQQQGDCPTGHAVITLAGALPAKAVVHTVGPVWRGGEQNEDQLLQDAYL
                     NSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYD
                     EENAHLYERLLTQQGDE"
     gene            complement(80427..80738)
                     /gene="ymdA"
                     /locus_tag="ACHY1N_000687"
     CDS             complement(80427..80738)
                     /gene="ymdA"
                     /locus_tag="ACHY1N_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmdA"
                     /protein_id="HFS4043033.1"
                     /translation="MFRPFLNSLMLGSLLFPFIAIAGSTAQGGVIHFYGQIVEPACDV
                     STQSSPVEMNCPQNGSVPGKTYSSKALMSGNVKNAQIASVKVQYLDKQKKLAVMNIEY
                     N"
     gene            complement(80859..81191)
                     /gene="csgC"
                     /locus_tag="ACHY1N_000688"
     CDS             complement(80859..81191)
                     /gene="csgC"
                     /locus_tag="ACHY1N_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly chaperone CsgC"
                     /protein_id="HFS4043034.1"
                     /translation="MNALLLLAALSSQITFNTTQQGDVYTIIPEVTLTQSCLCRVQIL
                     SLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPEDRVKIVVTVSDGQSLHLSQQ
                     WPPSSEKS"
     gene            complement(81250..81705)
                     /gene="csgA"
                     /locus_tag="ACHY1N_000689"
     CDS             complement(81250..81705)
                     /gene="csgA"
                     /locus_tag="ACHY1N_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli major subunit CsgA"
                     /protein_id="HFS4043035.1"
                     /translation="MKLLKVAAIAAIVFSGSALAGVVPQYGGGGNHGGGGNNSGPNSE
                     LNIYQYGGGNSALALQTDARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSAT
                     LDQWNGKNSEMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY"
     gene            complement(81746..82201)
                     /gene="csgB"
                     /locus_tag="ACHY1N_000690"
     CDS             complement(81746..82201)
                     /gene="csgB"
                     /locus_tag="ACHY1N_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli minor subunit CsgB"
                     /protein_id="HFS4043036.1"
                     /translation="MKNKLLFMMLTILGAPGIAAAAGYDLANSEYNFAVNELSKSSFN
                     QAAIIGQAGTNNSAQLRQGGSKLLAVVAQEGSSNRAKIDQTGDYNLAYIDQAGSANDA
                     SISQGAYGNTAMIIQKGSGNKANITQYGTQKTAIVVQRQSQMAIRVTQR"
     gene            82955..83605
                     /gene="csgD"
                     /locus_tag="ACHY1N_000691"
     CDS             82955..83605
                     /gene="csgD"
                     /locus_tag="ACHY1N_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm master transcriptional regulator CsgD"
                     /protein_id="HFS4043037.1"
                     /translation="MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQ
                     RSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPENYPYRDIENWP
                     HINGVFYAMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
                     KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR"
     gene            83610..83999
                     /gene="csgE"
                     /locus_tag="ACHY1N_000692"
     CDS             83610..83999
                     /gene="csgE"
                     /locus_tag="ACHY1N_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HFS4043038.1"
                     /translation="MKRYLRWIVAAEFLFAAGNLHAVEVEVPGLLTDHTVSSIGHDFY
                     RAFSDKWESDYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPLKRDFEKTVVFAL
                     IQTEEALNRRQINQALLSTGDLAHDEF"
     gene            84024..84440
                     /gene="csgF"
                     /locus_tag="ACHY1N_000693"
     CDS             84024..84440
                     /gene="csgF"
                     /locus_tag="ACHY1N_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HFS4043039.1"
                     /translation="MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNS
                     AQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIV
                     DIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF"
     gene            84467..85300
                     /gene="csgG"
                     /locus_tag="ACHY1N_000694"
     CDS             84467..85300
                     /gene="csgG"
                     /locus_tag="ACHY1N_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
                     /protein_id="HFS4043040.1"
                     /translation="MQRLFLLVAVMLLSGCLTAPPKEAARPTLMPRAQSYKDLTHLPA
                     PTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQ
                     NLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
                     IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGE
                     VGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKAERQNDILVKYRHMSVPPE
                     S"
     gene            complement(85364..85855)
                     /gene="ycdZ"
                     /locus_tag="ACHY1N_000695"
     CDS             complement(85364..85855)
                     /gene="ycdZ"
                     /locus_tag="ACHY1N_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415554.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HFS4043041.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGLKGLAISAATLLSGVVWAMVIIYGSALAPHLEILGYVITGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWKLVLPSLALGLVFGYAMKNSGLWLAARSAKTAHREQEIK
                     NKA"
     gene            complement(85957..86511)
                     /gene="ycdY"
                     /locus_tag="ACHY1N_000696"
     CDS             complement(85957..86511)
                     /gene="ycdY"
                     /locus_tag="ACHY1N_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone YcdY"
                     /protein_id="HFS4043042.1"
                     /translation="MNEFSILCRVLGSLYYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DELLTRLQKSCDMAQVSADYNALFIGDECAVPPYRSAWVEDATEAEVRAFLSERGMPL
                     ADTPADHIGTLLLAASWLEDQSTEDESEALETLFSEYLLPWCGAFLGKVEAHATTPFW
                     RTMAPLTRDAISAMWDELEEDSEE"
     gene            complement(86535..86876)
                     /gene="ycdX"
                     /locus_tag="ACHY1N_000697"
                     /pseudo
     CDS             complement(86535..86876)
                     /gene="ycdX"
                     /locus_tag="ACHY1N_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309438.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding phosphatase"
     gene            86916..87188
                     /locus_tag="ACHY1N_000698"
     CDS             86916..87188
                     /locus_tag="ACHY1N_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043043.1"
                     /translation="MNIGKAIINYAARRNMDITLIGDETVAFWEADNDCEWMFSYMIG
                     NDGFLHFKGNVYLPQEIKEELPACIDTDKKLKEVINFIAKEFISKK"
     gene            87201..87587
                     /locus_tag="ACHY1N_000699"
     CDS             87201..87587
                     /locus_tag="ACHY1N_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043044.1"
                     /translation="MFNIMIRKFGEMTFEKAGVARTEEEAMALVLVALRSSPEIIDAE
                     YVAAEGEIKEIKAVAKELGVKGFRKLKLSRESYVIGKQGQYLDENSAIVLLNKITRYG
                     FQIEQYKTCFELYEKGLLDTLTIVRA"
     gene            87900..88319
                     /locus_tag="ACHY1N_000700"
     CDS             87900..88319
                     /locus_tag="ACHY1N_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001767186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043045.1"
                     /translation="MKKIIAGVVLALGLVGAANANTYTYYVCNSYFEYKGDDTRYLSD
                     GDRYYHAPSGKYRGFIGVKVRVNDDNSQFAFNDPVYDKTIKSPKLKEDKNEKEEYYGS
                     EDGKSYIKYLHSIDGSPIFDVKKGDTSYSLISCREIL"
     gene            88383..90062
                     /locus_tag="ACHY1N_000701"
     CDS             88383..90062
                     /locus_tag="ACHY1N_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001406249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4043046.1"
                     /translation="MKTKLYSYIRFSSMRQNDGSSYERQIRMAREVAAKYDLELVNDY
                     QDLGVSAFKGANSKTGALSRFLDAIGRSVPVGSWLFIENLDRLSRADIVSAQELFLSI
                     IRRGITIVTGMDNKIYSLDTVTANPMDLMFSILLFIRGNEESQTKRNRTNSSALIKIK
                     SHQENPQNPAVAIEEVGKNMWWTDTTSGYVLPHPTYFPVVQEIVELRKNGRSTAEILD
                     HLNETYAPPPAVSNKKHSKWSRAMVERLFHTRALIGIKEVSVDGVNYELKDYYPRVID
                     DATFYHLKKNIGARAWNFGDKEEAKPIPLLSGIGLLKCDHCGCAMVKVKGTNKRSDQY
                     RYTCDATRSRRLDCEHPNWSFRGDQLEKAVLQLLADKIWIAEDKANPVPALKVQVDEI
                     SRKIDNLIALSAMTGATKELADQITTLNSERETLYNQIKMAEEEMYSVDSQGWEKLAE
                     FDLEDVYNEERLKVRFKIKQALKRIGCSRIDRNKNLFVLEYIDGKTQRVVIENSRGTR
                     KGRIFIDLKTINDRQILESNGLVLHPCLDMLTDKNWKPEQEIPGPLQEFGI"
     gene            complement(90136..91134)
                     /locus_tag="ACHY1N_000702"
     CDS             complement(90136..91134)
                     /locus_tag="ACHY1N_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043047.1"
                     /translation="MNTTLAKDIEFTAKSKRATPPVEYETRIIKVCQVHGWLYSGFVL
                     PVKKPFQNTKVCIEVNGKVKTPCISHVLTGQFTGKDRVSPPKKKFRFTEEEHLENARK
                     FYKPIGWDVLGLAEPYQGVDTKLILRCKCHGKIHKKGDLHNNRRQGGLTCPLVRGVLK
                     SIQNGRKQVIRNKFAQRPMHFYLIRVGEKFFKYGITTRKDPMQRVREHQKHTSEKITF
                     ECSHLFNIGWKAGDLEMGIKKNIQGKKIPRKVMNSGFTETLPISKLKDVKSFINEYIH
                     TNPSKPMYFDDTNAINLNNYISDEDIERDLSQWMKAPLAELTPEDLELDLSPLEAL"
     gene            complement(91181..91513)
                     /locus_tag="ACHY1N_000703"
     CDS             complement(91181..91513)
                     /locus_tag="ACHY1N_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043048.1"
                     /translation="MEEETPAEGTSINDLILAADTADDKVVFDEVDPSLVEAMKEPEI
                     VIEETKEESPAVEPVVEEVKSDVEEAPEVKVESPVANIFSDEAEHRSPAHDTDSFCDL
                     TGFQNYNN"
     gene            91604..92185
                     /locus_tag="ACHY1N_000704"
     CDS             91604..92185
                     /locus_tag="ACHY1N_000704"
                     /inference="COORDINATES: protein motif:HMM:NF045162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043049.1"
                     /translation="MMNDVRKACDIPFNFIRTKNGKAPSHPIDMEARIVTRIENEGLP
                     LIYHGFKGEYKSINSRIVLECESCARIRDITAKQFLHNPTVCPCNRSKYDNKYKKGQP
                     VLYVMRCGDVGKVGVSHNVLKRKHKLRCQNKMKFDIIEAFEFQDEKDAYAAELFIKKN
                     LVKGDFDIKEGATETFVYNEKMVRNIANVASIF"
     gene            complement(92217..92570)
                     /locus_tag="ACHY1N_000705"
     CDS             complement(92217..92570)
                     /locus_tag="ACHY1N_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase family
                     metallohydrolase"
                     /protein_id="HFS4043050.1"
                     /translation="MLSKHFSRKEFKCKCGKCDYDTIDAELLVILEDVREHFGKPVII
                     NSGNRCPTHNKNVGGATNSYHVRGRAADISVKGISPDIVHAYLDGKYPTQYGLGKYKT
                     FTHIDSRSKKSRWNG"
     gene            complement(92580..92927)
                     /locus_tag="ACHY1N_000706"
     CDS             complement(92580..92927)
                     /locus_tag="ACHY1N_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043051.1"
                     /translation="MAKNIFTEFPTYPVDQLSGIFINGISPESMTHDFEAKRVKHKQY
                     KECIRDHEKGTVFCVATLAKRPKYRFRVGQEVDVVNPYSFNCLGDARAVCVGTAPYYI
                     KGMRFIGYIFEMI"
     gene            complement(92966..93649)
                     /locus_tag="ACHY1N_000707"
     CDS             complement(92966..93649)
                     /locus_tag="ACHY1N_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000235912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043052.1"
                     /translation="MATSTNKRNALRTKKALRQWSEKATDTFERALGEGAIFASRALQ
                     KKINKNVDRPTRWTQQAVGNTNYKNRSGTRHQIFIKGARDKDKKIGSQDDYLKHYFDG
                     GKINKLVPIANGKVLDAHGNIKAIKGGKMMRNLENGNFIKVENKEGTFIMKKYKPKKS
                     RTKRARNGSAVAKRRLEKRIQKQSKRIVAVKSDKISTRYSTLGSWESNEAMMLENINK
                     HIKSRMKYV"
     gene            complement(93651..93821)
                     /locus_tag="ACHY1N_000708"
     CDS             complement(93651..93821)
                     /locus_tag="ACHY1N_000708"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043053.1"
                     /translation="MKNKLKKYFGYLLIVALTYNVAIRPLLTSFGLELPAMTVDEQLL
                     RTLAGVFSLLGG"
     gene            complement(93840..94118)
                     /locus_tag="ACHY1N_000709"
     CDS             complement(93840..94118)
                     /locus_tag="ACHY1N_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043054.1"
                     /translation="MTEIIYGGIGVIALICGGLWRLHRNQLATENRLSKLESSDALLN
                     QKFETMQNNHTQIAERVYQMEQTLHGIEKKVVAMDAKFDQVLDILKQK"
     gene            complement(94222..97968)
                     /locus_tag="ACHY1N_000710"
     CDS             complement(94222..97968)
                     /locus_tag="ACHY1N_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001767178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043055.1"
                     /translation="MGFEILVGAVIAGASAGMAAAATFSVMTAVAIGMAAGAMTLIAS
                     TVGAPKTPKVQSPDNAVTLGTSNDPKTVLPVLFGTTRTGAICVYKAISQRENNKLVQI
                     FAIAEGEIDHFKALHIDNKNVLISQNMTIRDGILDKGNIKDEYRKVLEVEFRTGKNPN
                     TALDLAKHHLGADWDDRYQGNGIATMCIVLRRDDKSLAAGVDILQPNSQVAVDVMGLK
                     IRNLETNAIEASTNGVDQIFHYLTNEKYGLSVPIENINVDSFLKVRKQVRQMDLHSNG
                     ACDPNASFKENLTSLMQTFGGVMFESFGRITLKLDAPDIVKHTFNEDNIMMGKVSLKT
                     GGTNGYFNTINAMYQEPSIDYSEQMLRYPADAENDATVRADGRIIAKDVEYRFVKSKD
                     QIDKLASIERNKSRITQVISFMTTDAFTAEVWDVISVTYDELKLNNSLWRITAIDRSI
                     DSGIAGMMTITATEYNSQVYTDLNYAATPDNRPTGLPDSMTVQKPTNFRIKATGETIH
                     GKNVTLTWDAPEDFNRYGFQIDYRVSGSPNWIKLGQTSQQIFNINALAKDRSYDYRVC
                     AFGIIARSEWVELVNQNPEVTYELPTPVIRIKNQGSSPGTFEGNDLIIEWENQQQLDV
                     MINGEANKFSDLFEAYIIKVTNKAGKSIQYRTRDPESWTYTLDMNQFNGLSRELTVEV
                     SVKGYNNSESAPARLVAINPQHKPMKGFSARGGFNTAFVSWADDVEHDYAGSIIQYAT
                     DNTFSDARAVTTNSVSHTSFDLADGDYYIRGAHYDIFGMDDAVWSEPYFMQMKSTISW
                     DDQDKEALEDLIGLQDRLDETIADAIAQAGANADAKIDAMHKQITTETGQTVQASADT
                     LKSLIATSEQASATKIDQVKAELKGDITKEVSASATTLKQAIATSEAASASKIDQVRV
                     EMDGKIAGVNQEADVKIDALKGTINSKYNLAVNADGRVAGIHMSATNDPAEPTRIIFT
                     ADKIAVAPQDGSEVCPFGIEGNKVYLDNAMIRNGAIGTAQINDASITTAKIGTAQING
                     AHIQHAQIGTGHIIDGSIDNAKIGNYIQSYNWNGNDGWYIGKDGTCHFRHANIRGHLV
                     ADSGEMNNVTINSSCRILGMLDANQVRGDFVKVVGRSFPHRQPNWPDGAITVRVEDDH
                     PFDRQIVIPAIHHNGSVRRGESSDHWDTCRLIVKKNGGVLYDRTATSGCMYSGVIDMP
                     AGHGAVTMTFEVYCKGVNNYNPSAYISDLTVMVTKKAATGISVS"
     gene            complement(97968..98387)
                     /locus_tag="ACHY1N_000711"
     CDS             complement(97968..98387)
                     /locus_tag="ACHY1N_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001351726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043056.1"
                     /translation="MLKTRLITDYINSLIGQEFVQGENDCNLIACKIIDILAGTDLYN
                     SLYKKYSTKEEGLKICKELSGYSNILQPIKKHFKLVTDDLQDGDLLVTAHKLGNRKYY
                     SVVPHYSGYGLVEEDGIWMTIPVSDIDYEQVYRFGGE"
     gene            complement(98434..99087)
                     /locus_tag="ACHY1N_000712"
     CDS             complement(98434..99087)
                     /locus_tag="ACHY1N_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043057.1"
                     /translation="MATIQESFSKLCTNLDFIEVYNDQTGQNVSRLTLPQLFSTGSMF
                     HIIEVITASGDVLRLTDGYFDLDYNGFTYLATGDFLQISSNTEEKEINNNGINVTVSN
                     VREEYITLIRNKQFDKSDVKIEMVFLNPNTGKVETTYPVFRGVVDSIGINIEHEDDEC
                     KNESEFQLNSIWEVLDKNARSHASDGIHRSYVGNENDLFFSRAGKWNSESKWFSSKK"
     gene            complement(99087..99647)
                     /locus_tag="ACHY1N_000713"
     CDS             complement(99087..99647)
                     /locus_tag="ACHY1N_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001767177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043058.1"
                     /translation="MFKSKNIKITDFTLKSKQPFFKAQSISGKFQRRFTGIHFYEAEF
                     TANFMAQDINEVKEFVARHLFGRPFSVPLSYFSKYTGDVRQMVTAAAGTARGGRKVRI
                     SNFTGTLKAGTIIQFENHKKIYTITEDVKSGGEMKLFPNLRQNVLAGEVIKYQNVEGE
                     FVLKTENIDWKIAQIGKMKFELVENV"
     gene            complement(99699..102041)
                     /locus_tag="ACHY1N_000714"
     CDS             complement(99699..102041)
                     /locus_tag="ACHY1N_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001406247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043059.1"
                     /translation="MTRHIVTIEGNNDGLRRSTNQAIDMLDNLSERAMNLDLSGGLSS
                     LSGTLRGTGGSLALAAGGFVGLAAGAVSAANAIGDYVKEYSEVSKATGLTVETLQKLE
                     KQFSGTGLTVEKFGDINKDTLDKLADAWRNGGGIEDDLESVGLKIKDYAEFMNDPQGG
                     MKAAIKVFYDMRKAGASIADVKFMMESLASDSSHMADELQKYGSYQEAVNAINQQTVK
                     ITNDTAEEYNKFSKNMDTLTDNLKGMAANALNPVVEGMNKLYNWFDKDWEKTALFNAL
                     KTFNERFEKARQNMAMANGGFINKHGYSSTGLAGGQASFNNKPNYPDRWVDKDGVTRD
                     KNGDPVITITGNKSDTGFTPTGQGGGVTGPTKKEQEEAEKAAEEARKAAEKAQKQRED
                     AIKKLNALDVRLHGQTAASIASQNKQLEASLKDLDTALDLGLISQQDAAAKRQQLLDQ
                     NAENIYKMMLGADPVDALNALTVLQQIRDNELESHKRLLDGKAISYEEYMRRVNDTEQ
                     NYSQIDSHLQGMDGFKTNQLTSGFDYQDSNNPFAKFNAIDKEKSEAEQDYKTDKLKID
                     GITDPAKRMEALEKLNENHQKRMAAIEKKYADARQSIADDMYGGFAAAMTLFGQENTK
                     AMQMAFNAHKAFSIGQATVNMWTAATDAWNDPTNVTTGQKIAAAALAVSQNMGSIANI
                     KSTNVSGMAHDGIDNIPREGTWLLDKGERVVDQRTNGDLKDFLSAQKSGGGNSQPIEV
                     NAPLNINGNVNSSDKMVMDAIKRHAKLVAQAVEDAQRRKM"
     gene            complement(102053..102355)
                     /locus_tag="ACHY1N_000715"
     CDS             complement(102053..102355)
                     /locus_tag="ACHY1N_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001434083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043060.1"
                     /translation="MSITLFWKLYIFDTYLEPQSPAFHDMQNAMLQYSMYMTSQGMTR
                     ETARKLKPSQFQLIREEKLFKTKEELEEIARKKEEERKAAMLNMFDPSLLEKLRSG"
     gene            complement(102424..102732)
                     /locus_tag="ACHY1N_000716"
     CDS             complement(102424..102732)
                     /locus_tag="ACHY1N_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome"
                     /protein_id="HFS4043061.1"
                     /translation="MNINEMLKALSPKRESLTIGGFTFYARPMSVKEFNEHVFNTDKD
                     DRDERSILRCIEDEDGKPVFESMEQVKALYTNVRSELIGLVAQASLMQEPAVIENEVK
                     "
     gene            complement(102815..103285)
                     /locus_tag="ACHY1N_000717"
     CDS             complement(102815..103285)
                     /locus_tag="ACHY1N_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001695774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFS4043062.1"
                     /translation="MTTKFDIFSGGLVGLFLHEEVTNTDLDSESYLEIPECAAFPETG
                     VERSTVDVPNFGGPYNRKLVGRMSVPDIELSINYMPGNEVHEKLIKATEDGKRVQIKI
                     AYYIDATKKSGVHIAYNGFLSKTTMTGGEDAVVGRTFTFVVDGAPVKQAVFQKL"
     gene            complement(103339..103641)
                     /locus_tag="ACHY1N_000718"
     CDS             complement(103339..103641)
                     /locus_tag="ACHY1N_000718"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043063.1"
                     /translation="MAFWVDGALGNRAGKANQGWFDIPNGWTADAFGTISFCAHSSGG
                     GGGDSELLIHGLCVSGSHKGHDWGQIHSCIAPQGAVITVSTNRGIAHLRYRRLSNR"
     gene            complement(103641..103946)
                     /locus_tag="ACHY1N_000719"
     CDS             complement(103641..103946)
                     /locus_tag="ACHY1N_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043064.1"
                     /translation="MAGWINQRMSNAISIWANGGYFDIPNGWVTDSCGIVFAHMEAIN
                     GAGDLDSELAVNGLIESGHHAGDAGSWGASSLVGAGATVSFTLGKGSLHYFKFRRMH"
     gene            complement(103949..104245)
                     /locus_tag="ACHY1N_000720"
     CDS             complement(103949..104245)
                     /locus_tag="ACHY1N_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043065.1"
                     /translation="MGYWVSSEINTKIDALKWHVFDIPNGYGTARAGVAVMRHNAGGG
                     WSDAHINVDGLTVARRRGGTNWGSTINSFVPAGCTVSFGLGGEGGVEYFKFMEF"
     gene            complement(104284..107694)
                     /locus_tag="ACHY1N_000721"
     CDS             complement(104284..107694)
                     /locus_tag="ACHY1N_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001695771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098024 - virus tail, fiber [Evidence
                     IEA];
                     GO_process: GO:0019062 - virion attachment to host cell
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HFS4043066.1"
                     /translation="MQSIQFKRTNVAGKKPTPEQLQVGEVAINLKDHVIFTKDRDHEV
                     VQISVSPETHAALESKVDANKQELDSTIAVNDRNIHAKVDEIKQTTDATIAANHAEIN
                     NKVDVIKRETDATIEANKNKAASDLAGVKAELSDTINANKNAAAVATQELDTRINKKV
                     DDIKSRTDATIASNHKAINDKVDLIKAETDRTIAANQAYAENQLTDTYNNLTGVIAAN
                     KQEAADNVAALTRDVEAKNSAIHSKVDNNKSYTDSELARLESRIDAADGSADGKYIKK
                     HVNTYTDGYLLSKTANYFDDPSARNLDYFGAFRMNDLAGHIALALHVPHPSGVNHARG
                     FEFTYGSNPHATVRTYGYDELGHLAYSHRMYHEGDKPTPAEIGAYSKAEIDRLFQKTL
                     NFGIEGGWFKLGTLTMPQQHGRTAKIRLVGGNGYNVGMNGQANIIELVIRCGNNSPKG
                     VVFNAYYSIWYHEQHFCAIPTDGDNYDLYAYYGAHTGFVLAEYQVSSGGVSLNLLDTP
                     EYLGGEKPVADEIFDALNISSFNNFSNRGTLNFGGNHQGQYDIEHLNEQPTNAKKMLR
                     RFRSCAPATIWHETVDDNAYRLATGYEDTNQELLLTATSGLHVKKLTLDGGVTGNSGI
                     DIRRGPNESSHFNFMDYRTGQDVRNGWFGFGDGTTKDFIWWNDNGQNSINLIEDGELH
                     ITGGKGQKIVMNSEVALSENARLAVKGGNYGLILRNDGSSFHILTTDLKDSFGSWNNR
                     RPFSYDFADGGLYLGGTATARCLHLGIDGSTRLEDNLFFKAGSRQSMDYMELVHWGAS
                     NTGRNNVLSLRDSKGFFAEFERLGDNTIKNTFFGKLKVNRGSDAIIMNAESGDSSIYL
                     LGTCADNNNWYIGKGGADNGLAFYSYATNAAINITNAGDIALSPKGVEMTHVNNVRFY
                     VHGERWTASQSGGWGDQWGLEAPIFVDHGYVSPDCYYPIIKGRSLITNQGYTTAVDFG
                     MRRVPQNWGQAIIRVGSAEASPAPGHPQAVFEFHHDGTFYCPGNGNFNDVYIRSDRRL
                     KINVEDYEENAVDKVNKLKVKTYDKVKSLNDREVIGHEIGIIAQDLQEVLPEAVKTAN
                     IGGFDNPEEILTISNSAVNALLIKAVQEMSEENKLLRERLAAIEAKLG"
     gene            complement(107768..108601)
                     /locus_tag="ACHY1N_000722"
     CDS             complement(107768..108601)
                     /locus_tag="ACHY1N_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001417879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043067.1"
                     /translation="MNITQDNLDIFTGSHVEVSVSTMVDNQPDFFDPAFSPIENIAAF
                     PTITESTEIQTLEEYDQDATGKLAGYRKLEPTTLTLNRVLDDEHQAMLMKAVEDKTPL
                     RFRMFYVVNSGYSAANTGYYVIYDAYVTSHKTRGSDNKAVTLEFKLEPDGGILARGIA
                     TEGKILRQGDYGVGSGVSPFTGPIDSEALAGNRFVTYQGSSASNPFSADTSLIHVQPN
                     EDGGWQLTCTASGAPRLRVRTVQKDGNSGWVKVYSTEEKPTPAEIEAVSIHDRIDFGE
                     Y"
     gene            complement(108611..109033)
                     /locus_tag="ACHY1N_000723"
     CDS             complement(108611..109033)
                     /locus_tag="ACHY1N_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043068.1"
                     /translation="MLATVNNMPRLKIKRALQDIIEQDLGLALNVEQTQQGFSDDVVC
                     WITGMNETYTRVRGGNAMQAECVIEMQLYSQIHETKIHEGICQIIQIQPDNPRFKDLG
                     FSISDITPVASNTDYDDDSSDGGIVGTLSLKFSYLARF"
     gene            complement(109017..109307)
                     /locus_tag="ACHY1N_000724"
     CDS             complement(109017..109307)
                     /locus_tag="ACHY1N_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043069.1"
                     /translation="MFKLSESQLSRMFRSAPVFSVEGGKSIRAYHEITTTDESGVMTE
                     TEFLFCREGDLKQGDIVIVENQRFKVQYVKRNGDNTCDCFITLAGGTHARYR"
     gene            complement(109499..111505)
                     /locus_tag="ACHY1N_000725"
     CDS             complement(109499..111505)
                     /locus_tag="ACHY1N_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFS4043070.1"
                     /translation="MLKFRRDLNGYGGVINEGQNDQYEFEIAFSSEQPYQRRFWDEQN
                     QEMVVLDEILVHTPEAVDLSRLNNNAPLLFNHIFDNHIGVVCNARIDADNVGRALVKF
                     SKHGTLSNDIRNKVIEGTMEKISVGYDIKEYRIDYAKGQLIVTKWEPFEISFVTVPAD
                     DTVGLNRSLNTITVNLEAKRDMTKEQIEEIKNEEPAQVEETPVEENKEPEVEKTQERQ
                     VEENKEDENLEDGKDAKHPESVDDDSSTVRETEEVKEEREAAPVEEEKTEEVAERSEE
                     DELEIREIARELNINEDDEEFQRALANKEITPEAFRTKALNNITNAQRNNEQIKDSKM
                     EKTFDLNNVIRSLVDGAALGANEAEYSAMAAGAAMQRGRAARGGSVFVPAAALRAASE
                     GNTKATLTDITDEKLLTESYVEMLLPQSVLGRLGVTVLSGLNAPIAVPKMTTSSVDAF
                     GFVDENGAAPESKAEFANVKMAPKTFAGGNPISRQSLKTVPNIATLITDHINKAVRIK
                     LEQLILSDKDNTRGPKGLVKQLVDGGRVAKKAAFSYKDFLKEIAALTDAGVPAQAIKF
                     AMSGATAAELESTLKDNGVSGYIIENGKLAGYDVVTSGVIPADHIVLGDFSGIMIGEW
                     GGLELDMDDTTYRAQSAIVPRIWVDLDFTVVQPEALKVLHISAE"
     gene            complement(111551..113062)
                     /locus_tag="ACHY1N_000726"
     CDS             complement(111551..113062)
                     /locus_tag="ACHY1N_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000482547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4043071.1"
                     /translation="MFNLFRRKKAVETPVKTNHRQQQQKIFIDKQVEKFQKDLSKRSL
                     GLVGDRIDGSLQQDTITGTFNKALKSNGKRLYDQGRTLALNTSVGSRYTQYITDMVVG
                     TGLDPKPSIVKSNGKLDSALNKQIENAFWKWAQNAKRFSRNGRFNFRELLVMAERERV
                     MGGECFIVLTKENNELNVSILSADKCDWSLNREVSKERAIYQGIEYDVETMKPVAYWF
                     RKVNLLTQTYTGDNYRVEASQVCHYYQPLTAESLRGVTDFLPVIKDIAHQDAFRETAI
                     VQKRIAASSMGFIERPKDSGDDFDTGEEDEQYQAPEVVQDFAPGTIQELPEGATIKSI
                     QATQSGDDFNSFNDAMFTSVSMGLGVFKQGLTGDCSQINYSAARFGELTQRNRIKALQ
                     NKLIETVVLAIFEAYLRHYSARGVVPIRITAIPHIIDNTTIIRPRFESVDPFKDVSAE
                     IALIDNGLKSRTAVILERGDDPEKVFSEIQAEKSALNIIVNGEGEEKNSPADP"
     gene            complement(113073..113567)
                     /locus_tag="ACHY1N_000727"
     CDS             complement(113073..113567)
                     /locus_tag="ACHY1N_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001767166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043072.1"
                     /translation="MSLELIPLVIRKGEKITLANEEGVTIQVGNSKGIIYQVDDTPAN
                     HEIKTLDFAEGKYTIVTTLEDELVSMQELTVLPVFAKQSKKEYLRETIATIEQVIFAR
                     LSGDEAALSQMTVKGNTFAYESLAVLQTLKVDYERQLSKLIQAERRKQGISPIKNIKV
                     RLTR"
     gene            complement(113640..115547)
                     /locus_tag="ACHY1N_000728"
     CDS             complement(113640..115547)
                     /locus_tag="ACHY1N_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase gpA endonuclease subunit"
                     /protein_id="HFS4043073.1"
                     /translation="MKLISNKAKLKKILKNAAKYITPPPKLLPSEWCEANMVLVDGPQ
                     AGDKVKLLSFQKGMIDAPFLENKKKYVLMTSAQIGKTTILNGILFNQMANDPCNMIIG
                     QSTAKEMSQYLAGKIRPSIEACDALKDVVTDKNDRNAVNNNNQLQLKTNHFLYMVSLT
                     SPSTLRGKTAKVGLLDEIDAATASEEGDPVALAANRLTTFGDEGRLVVSSTPTSKLGS
                     INQQWLSSDMRMFFVPCPHCGEHQVIEWENVQFEWRNIDGKNLPDPDTARYICPHCKN
                     AWTEGERIRAVAQGEWRATRESEVAGFWISRLYSPFSTIRACVVDFSHAWQSFDLQSF
                     YNTVLGKVYDDQDTAVEANELEQLKTDVSIENIPDDVIFLCSGIDQQLDRAESTILGV
                     AKDKVYILDHRSFYDHNCERYESPVWDRLVNFKKTKFYNVNGERVPMLASFLDTSNGR
                     FTQAGYRICGKWKNLHAIKGSSSGNAPVIPVKPTRTGGHELLMLGVNVGKSAVREMLV
                     RNLKDNPHIGLEISETVPDDYLDQLLSESIKRTTTGVRWVKNPGSTRNEALDCLVYSY
                     AASRYVLSKMSWDKLIAMKDSLNRVVEEPVKAPKSQSNEQIEETKPITRPQRQNIARR
                     PNKGRSWVTSF"
     gene            115634..116236
                     /locus_tag="ACHY1N_000729"
     CDS             115634..116236
                     /locus_tag="ACHY1N_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000906790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043074.1"
                     /translation="MLINQQERDELELALSCTDHEYRLPVKHKHLKTDYTTSGFSREE
                     AKEILIEFYRDNGYRDVRNFFSKHRTSHTEFRRVRDWFDFDIKRFYRIDDGPIYRLQW
                     KPLREVFKHERLNHAVTRYRNEAFKKGYGDTRELFVELANVRYSHYYNDPKGFFEVLR
                     KVDISRGTYYSRLRQYGIKAEFFMSVDDGELFPIKCKSSK"
     gene            116272..116496
                     /locus_tag="ACHY1N_000730"
     CDS             116272..116496
                     /locus_tag="ACHY1N_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001417874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043075.1"
                     /translation="MTTKATRGRPCRFDREQLAAIVKAYYQAPKGKAEKEQVLSEHGI
                     SIAQFYKSLHKVDLKFFVQVDGEMVEATGI"
     gene            complement(116800..117633)
                     /locus_tag="ACHY1N_000731"
     CDS             complement(116800..117633)
                     /locus_tag="ACHY1N_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001434081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043076.1"
                     /translation="MNTVTTMNTAVKTASVSLVVDNEVAKMTLREIADLIGVRFSNLE
                     TSMNRLVERQVIRKPATKNFEKINNLGFAVTVKDYVFEGEQGRLDSIVLIAQNVPEFT
                     RQLVDRWNYLEEKLKTANNTPVNPYADFEETDWIELALDEKRKNKKLIELHIRKSVDS
                     HSMTRLLGAKKGATKVKEALTALRTAGYIERVYDENNKPCGYVANDSSLSFCRMNAHY
                     QLEFTVDVLPVLVELGVLEEEQKATLKLPQPNNTILIQNKAAKQIRESGNVISLVDFG
                     I"
     gene            complement(117732..117878)
                     /locus_tag="ACHY1N_000732"
     CDS             complement(117732..117878)
                     /locus_tag="ACHY1N_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043077.1"
                     /translation="MNTTKKIDGRKNPNRKPWTPNLNFSMVDFHERQRRIQEEIDRAI
                     AESK"
     gene            complement(118001..118468)
                     /locus_tag="ACHY1N_000733"
     CDS             complement(118001..118468)
                     /locus_tag="ACHY1N_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043078.1"
                     /translation="MNHKMTTTTPFILLGLDADSFHNDKLMKMFRERGYNILFNTDES
                     HFSSAWYAFHRNKKPTIVVNCLTDEDREKYQNIPAIIVSEYLPFEVRDYDIDLGSFFS
                     VCDLDEAMFNYGKETAQEAPEEDEQDEDDDDYAPICFSSQNGFYGYDEGLDML"
BASE COUNT        30401 a        29729 c        27674 g        30904 t
ORIGIN      
        1 ggctattcca ttcgaaggtg agcgccataa tgcacttgat gacgcccgtt accaggcaaa
       61 atacgtttca gttatctggc aaaaactgat cccgagtcag gctgattttt aatgttcaac
      121 cgtcgccagt tgtcgttgat attctgcaac tggcgcgttc cggagtgata gccatgagcg
      181 aacagtacct gataacgctc gacgagtgga aaccaaaacg gttcagtctc ccaataacaa
      241 acactaccct ggtgaaatac ggaaaactag gatacatcgt tccaagacca caaaaaattc
      301 gtgggcgttg gctgatagat cgccgagcag tatttgttgg gcctggtgaa acgggaattg
      361 cgccggaaat tcatactggc gatgatgatg cactgaagga gattttaact catgtcaccg
      421 aggccacgaa aaaacagcac tgacgtagcc ggtctttacg aaaagtttga tcgcagaact
      481 ggcagagttt actaccagta taaaaatcct gtgactggaa aatttcacgg actcggaaca
      541 gacaaaggta aggcagaaaa aatcgcttcc acagccaatc agcggatagc tgcagcagaa
      601 gctgaatatt tcatgcgcaa aattgatgaa agtccgtcag caacaaaacg tcggggtatc
      661 agattaaagg catgggttga tcgatatctg aaaatacagg acacgcgact gaaaaatgga
      721 gatattgcag ctacaactca caaagaaaaa gcccgaatgg ctgcatacct ggtttcccgt
      781 ctgggaaacc acccattgaa agaactggaa gtaagagact ttgcattaat actggatgag
      841 tggctggata aagacatggt cagcacagcg agagtaaatc gtggattatg ggttgatatt
      901 tataaagaag cacagcatgc aggggaagtt cctcctggat ggaatcctcc ggaggctacc
      961 cgtaaaccga tccctaaagt aactagagcc aggctcaccc tggaagactg gcaaaaaatt
     1021 tacaacgcaa cgcctgaaaa acactttatc cgtaacgcaa tgcttcttgc gattgttact
     1081 ggtcagcgcc gtgatgacat ttgccacatg cgtttttcag atgtgtggaa cgaacacttg
     1141 catatcaccc agggaaaaac cggaatgcgt ctggcgttac cgcttacact acgctgtgat
     1201 gccattggga taacgttaaa agaagttatt gatgggtgcc gagacagaat attaagtcca
     1261 tatctaatcc atagtcggca ccagaaacaa ccaaagccga tgagtaaaga caacctgagc
     1321 gactactttg ccaaagcacg ggatctggct gggataactc caccagcagg aaaaactccg
     1381 ccaacatttc atgaacaacg ctccctgtca gaacgactgt accgcgcgca gggtattgat
     1441 acaaaaacat tactgggaca taaagtccag gcaaccaccg atcgttataa cgatactcgt
     1501 ggtcaggaat gggttaaatt ggttgtttga cgaaataaat gcagctgaaa aatgttgata
     1561 ttgctttgct agtgtaaaaa ccccggcatc aaccggggtt cggagactaa tcttgatcag
     1621 gttcctgctt agaataatgt tttccaacaa taaatgccgt aaccaatgca acaagatcta
     1681 ttgaaacgag agttccggca agaactgtct cccccatgac gccaaagaca gtggcagcta
     1741 agatgatcaa tattgccaac caaaaagcct ttgtttgacc atctctggca atatcaatgc
     1801 tatcagccac tgttttatgg cgatgagcct gctctttttc ggtcaactca acaagtcgat
     1861 ttgcaagccc aggcaccagt tgatcatact ttttaagcat tgaaggtggc ggaacaggcc
     1921 cctgaaaatg ctggcaaaca atagcccgca cctgcggact atccaaaacc ctgtttaaga
     1981 cctctggatt ttcgattact cgagaaacca gttcattatc cttttgttct tcacaagtga
     2041 gtttggtgtt ctcactttct ttttgatctg gcattgttca gcttttcaac gttaacggat
     2101 accattgctt tttggaaatc gcctctgata gccgcagcat cctgacgcaa agcggaaact
     2161 ggattcgctg gcatgccatt tgctgaaacg accgtcgggc tcagggctat aaccgagcca
     2221 atggcttgta acaaagccac acttttacgc ttcatagtca ctcctgagtt caatgggatt
     2281 caaaacggat tcaaagtgaa tcttgatagc taattctaat accacattat gtggtttttc
     2341 aacacgaaga aatcacatca aaaatctcat tcggaaagcg atatgggtaa acaaactgga
     2401 atacttttct gtcctagtaa gctcacccat gtataaaaat gctgtaaaat gcgtggtcct
     2461 gttttgggga aaagttttgg agagattttg gagaaaggaa aaaattgaat aaattcaaaa
     2521 tcctgaaagt gtcccgcctt atgaataaaa aggtggaact cgaatgatcg gtcgactgct
     2581 tcgcggcggt tttatgaccg ctatctacgc gtacctgtat atcccaatca ttattttgat
     2641 tgtgaactcc tttaacagct cgcgctttgg catcaactgg cagggtttta ccaccaaatg
     2701 gtatagcctg ctgatgaaca acgacagcct gttacaggca gcgcagcatt cactaacaat
     2761 ggcggtgttt tcggcgacgt ttgctacgct tatcggttca ctgacggcag ttgcgctgta
     2821 ccgttatcgc tttcgcggta agccgttcgt tagcggaatg ctgtttgtgg tgatgatgtc
     2881 gccagatatt gtgatggcga tttctctgct ggtgctgttt atgctgctgg gtattcagct
     2941 tggcttctgg tcgctgctgt tctcgcatat caccttctgc ctgccgtttg tggtggtgac
     3001 ggtgtattcg cgcctgaaag gttttgacgt gcggatgctg gaagcggcga aagatctcgg
     3061 tgccagtgaa tttaccattc tgcgaaaaat cattctgcca ctggcaatgc ctgcggtggc
     3121 ggcgggctgg gtgttaagct ttaccctgtc gatggacgat gtagtagttt cttcgttcgt
     3181 caccggacca agctatgaaa ttctgccgtt aaaaatttat tcgatggtca aagtcggcgt
     3241 atcgccggaa gttaacgcgc tggcaaccat attactggtg ctgtcgctgg tgatggtaat
     3301 tgccagccag cttattgctc gtgataaaac gaaaggtaac acaggggacg ttaaatgaaa
     3361 aaatggtcac gccacctgct cgcggcgggt gctctggcac tgggcatgag cgccgctcac
     3421 gccgatgaca acaatacgct gtatttctac aactggaccg agtacgtgcc gccaggactg
     3481 cttgaacagt tcaccaaaga aaccggtatt aaggttatct attcgactta cgagtcgaac
     3541 gaaaccatgt acgccaagtt gaaaacgtac aaagacggtg cctacgacct ggtggttcct
     3601 tcaacctatt acgtcgataa aatgcgtaaa gaagggatga tccagaagat cgacaagtcg
     3661 aagttaagca atttcagcaa cctcgatcca gacatgctca acaagccgtt tgacccgaat
     3721 aacgactact ccattccgta tatctggggg gcgacggcga ttggcgttaa cggtgatgcg
     3781 gtagatccga aatccgttac cagctgggcc gatctgtgga agcctgagta caaaggtagc
     3841 ctgctgctga ccgacgatgc ccgtgaagtg ttccagatgg cgctgcgcaa actgggctac
     3901 tccggtaaca ctaccgatcc gaaagagatt gaagctgcat ataacgagct gaaaaaactg
     3961 atgccaaacg tcgcagcgtt taactccgat aacccggcta acccgtacat ggaaggcgaa
     4021 gttaacctcg gcatgatctg gaacggctct gctttcgttg cacgccaggc gggtacgcca
     4081 attgacgtgg tgtggccgaa agaaggcggc attttctgga tggacagcct ggcgatcccg
     4141 gcaaatgcca aaaacaaaga aggcgcgctg aaattgatca acttcctgct gcgcccggat
     4201 gtggcaaaac aggttgccga aactatcggt tatccaacgc caaaccttgc ggcgcgtaag
     4261 ctgttaagcc cggaagtggc gaacgataaa acgctctacc cggatgctga aaccattaaa
     4321 aatggtgaat ggcagaatga cgttggcgca gccagcagca tttatgaaga gtattatcag
     4381 aagctgaaag caggacgtta attcagcaaa cgggcggtgg tattaccgcc cgttttttag
     4441 ttagcaagga tgtggctaat gagtcaggac agtaaagttt tatcccgcgc ttttctcggt
     4501 atcggtctga tattgctcgt tatttctgca atcatctttt attaccattt tacttttacc
     4561 aaaagcgcgg ttcatacaga aggaatcatt gttgatgccg tttggtacaa caatcactca
     4621 aacgacgtcg atgataatgg ttcctggtat ccagtggttg cctttcgccc tacgccagat
     4681 tacacgctaa ttttcaattc gaatatcggt agtgattttt atgaagatag cgaaggtgac
     4741 agagtcaatg tctattatcc gccagggcat ccagaacaag ccgaaataaa caatccctgg
     4801 gttaattttt ttaaatgggg ctttgttggc atagcaggca ttattttcgg tagtgtcggt
     4861 ctgataatca cgctcccctc caccaaaaaa tctcgcagga aacggaagtc ccgcccatga
     4921 aaaaattcat tatactgctc agtttactga tactcctgcc tctggtagca accagtaaac
     4981 cattgattcc aataatgaag acacttttta cggatgttac cggtactgta ccggatgctg
     5041 aagagatcgc acgtaaagcc gagctttttc gccaacaaac gggaattgca ccgtttattg
     5101 tgattttacc cgacattaat aatgaagcca gtctcagaca aaatggtaaa gcgatgctgg
     5161 cgcatgcgtc atcttcattg agtaatgtaa aaggaagtgt tctgttacta tttactaccc
     5221 gcgaaccacg gttaattatg atcaccaacg gccaggttga aagtggtctg gacgataaac
     5281 atctcggcct tctgatagaa aatcacacgc tggcttattt aaatgcagat ctctggtatc
     5341 agggaatcaa taatgcattg gctgttctac aagcacagat attaaaacaa ccgacgccgc
     5401 cactgacgta ttatccgcat ccaggacaac agcatgaaaa tgctcccccc ggcagcacca
     5461 acacattagg ttttatcgcc tgggctgcga cgtttatctt attttcctgg atcttttgct
     5521 acacgactcg ttttatttat gcgttaaaat ttgcagtggc gatgactatt gccaatatgg
     5581 gttatcaggc tttatgtttg tatatcgata atagctttgc gattaccaga atatcgccac
     5641 tctgggcagg gctaattggt gtctgtacgt ttattgccgc attgttattg acgagtaaac
     5701 gataaaagag gccggaaaag tgcgcgtgta ttatgccgga tggggcgcga acgccttatc
     5761 cggcccacaa aacccgcaaa ttcaattaat tgcgtcccct tgtaggcctg ataagcgtag
     5821 cgcatcaggc aatgcttcct gctttataat cccttcagca acttttcaac aaactcaggc
     5881 accacctggc ttgccgggcc gtaatatttc tcggcaaatt cattaccgac ctgacttggt
     5941 tcgagattca gttccacggt gtgcgcgcca tgcagtttcg cttcgtgaac aaacccagcc
     6001 gccggataaa catgcccgga agtaccaatg gcaatgaaaa tatcagccat cgacaacgcc
     6061 atataaattt catccatgcc gagtggcatt tcgccaaacc aaacgacgtg cgggcgcaag
     6121 ggtgccggga actggcaaca atggcattta tcttctggcg taacgtctcc ggtccagtcg
     6181 agaacctgac cactttgcga acaacgaact ttcagcaatt ccccatgcat atgaatgaca
     6241 ttggtattac ctgcgcgttc atgcaggttg tctatattct gcgttaccag caaaaagcga
     6301 tcgccgaggg cgtcttgcag tttagccagc gcaagatgcg cggcgttagg ctgaatttct
     6361 ggctgctgca gctgtcgacg acgggcgtta taaaacgctt gcaccagttc aggatcgcga
     6421 tcgaaacctt ccggcgttgc cacatcttca acccgatgtt cttcccacag gccatctgcg
     6481 gcgcgaaagg tacgaatacc tgattccgca gaaatccctg cccctgtcag tacgagtact
     6541 cttggttttt ccattgcttc cggcaccact ttatctctga aaaaaatacg ctgacgcaaa
     6601 cgctcgcgca ggcggcgttt atttttacga aaacgactta accgatgacc ccgacgcgac
     6661 agcatagcaa cctctgttgt ttaatcggtt agatgtagga aggccgcacc acgcattcct
     6721 cccgcatcac cgtggcgcgc gcgttcaatg cgcggaacac gagctacagg taagagatga
     6781 cgaggcagcc tgtccgccag ttgcgttgtg attgccggga aattcgataa gccaccacca
     6841 atgacgacca ggtcagggtc aacaatggtc aggatatttc ccagacaaac cgctaataaa
     6901 tccagataac gctcaacgtg cgcccttgcc tgctcatcgc cttgatcata aagcgcaata
     6961 atttcgggag cctgcaacgg ttgatgataa tagtgttgat acagccacgc aaaaccgcga
     7021 ccagacagat aattttcaat gcagccatgc tgaccacagc cgcagcggcg taacgggaaa
     7081 tccaacccca tcatggttaa cgcatcaacc ggcagacgca tatggccaaa ctcgccggta
     7141 atgtagcttt taccggtaat cggtttgccg ttgaaaatca gcccgccgcc aacgccggtg
     7201 ccgagaatca accccatcac cagtggatat tgagtaaatt catcatccca ggcttctgaa
     7261 agggcaaaac agttggcatc gttatcaagg cgtacatcgc gatcaagacg tgcgctcagg
     7321 tcggcacgca gcggtttacc gctggcagcg gggacattgg cggcatacag cgtaccatct
     7381 tctgtttccg gcattcccgg aataccgatg ccgacagaac ctttacagcc aaaacgttgg
     7441 tcagcttcag ctaccagctc acacactgca tctaaaaatg cgtcatagct gtcacgcggt
     7501 gtcggcaccc gcttttccca ctgcaactgc cgaccgctat caaacacgcc aagcgcaatt
     7561 tttgttccac caatatcaaa cccgtaatac attgccgctc cttgttttaa tgtactgcct
     7621 ttactggccg ctaaggactc gcgcagggtc aatattactg gcgcgccgcg ccggatacca
     7681 acttgccaaa agactcagca acaatgctgt gaccagtacg tagaagacgt ccagccagtg
     7741 caattccgat ggcaggaaat caataaaata gatatcgctg gagaggaact gatgaccgat
     7801 caacttttca atccactcaa taatcggggt aagttgcagt gaaaccacca caccgataat
     7861 caccccacac aggctgccga acagccctgc cagcaatcca taccagacaa agatggcgcg
     7921 aattaaacca tctttcgccc ccagcgttct taatactgcg atatcgccac tcttgtcttt
     7981 caccgccatc actaaggtgg agacgatgtt gaaacaggcc acgccaatca ccagtaccat
     8041 cgccagatac ataatggcgc ggatcatctg gatatcgcga tacatatagc cgtaagtacc
     8101 aatccaactt ttaatataaa catagctgtt ggtcacttca cccgcatcgc gtaccagctt
     8161 attggcgttg aaaacatccg tcattttaag ggcaatacct gacacgctgg aacccatatc
     8221 aagatattgt tgggcatccg ccagcgggat catggcaaaa ctgtgatcga gttgaccact
     8281 caactgcaaa ataccggcaa cgtgcaaacg cacacgtttt ggctgcatca gtttatgctc
     8341 gggattcgag ttggggatca taatcgacac ccaatccccc tgcttcactt tcagcgcatc
     8401 cgccacgcct ttgccgatga taatttgctg ttcgcccgct ttaaaattgc gccacgcatc
     8461 gccctggaca aacgagggta atgcgctcag acgctgttcc tgttgcgggt taacgccctt
     8521 cacctggatt gcgcgaagat tcgcgccact ttccaccagc ccggtgaaat tgatatacgg
     8581 cgcagcggcg gcaatacccg gcactttttg cacgtgatcc agtgcttcct gccagttagt
     8641 ccacggctga tccaccgcct cgatttcacc atgcggcacc accgccagaa tacggttgtt
     8701 cagttcgcgt tcaaagccgt tcatcgcgct taagccgacg atcaataccg ccacgccgag
     8761 ggcaatgcca atggtagaaa tgacagagat tagcgacacc atgccgccgc gtcgccgtcc
     8821 gcgactaaaa cgcaggccaa ttaataacga taaaggcatc gccattactc cgcccccatc
     8881 aggctcagtt ccgccgtcag acgaccatca cgcatttcta actggcggct catacgtttc
     8941 gccagttgca ggtcgtgagt aaccaccagg aaggcggtgc cctgcaagcg attcaattcc
     9001 ccaagcaact ggaagatgct gtcggcgtta cgcgcatcga ggttaccggt aggttcatcc
     9061 gccagtacca ggcgcgggtt attcaccagc gcacgggcaa tcgccacacg ctggcgttcg
     9121 ccgccagaaa gttcagatgg gcggtgattc gcacgatgct ccagccccac cgcttttaac
     9181 atctcaagtg cacggctgtt gatttcagcg ggctttttct tgccaataag cagcggcata
     9241 gccacgtttt ccagggcggt aaaatccggc agcaggtggt gaaactgata aataaagccc
     9301 agcttctggt tgcgcagctc tgctttcgcc gccgaagaca gtttgctcat cggttgaccg
     9361 ttaaagatca catcgccgga ggttggcgta tccagcccgc ccaacaagtg cagcaaggtg
     9421 cttttaccgg aaccagagct accgacgatc gccatcattt caccttcgcc gacgctgaaa
     9481 ctgacattgt gcagcacatc ggtttgcaca ctgccttcct gatagcgttt gcacaggttg
     9541 tcgcattgca acaggatctt attcataacg taaagcctca gcgggttgag tggcggcagc
     9601 gcgccatgaa gggtaaagcg tagacagcag cgcgatagcc atcgccacca gcgcaataac
     9661 aatgacctgt aaaggttcga tagcgaccgg cagcgccgcg ccatcaagca ggacgccgat
     9721 tatcggcatc agattattta actggctggc aagcagggcg ccaagcgccg ctccgaggat
     9781 cgcaccgata atcccggcgc tggccccttg caccataaag accatcatga tttgtcgcgg
     9841 agttaagcct tgcgtttgca ggatcgctac ttcgccctgc ttctccatta ccatcagccc
     9901 tagtgaggta ataatgttaa acgccgcaac ggcgacaatc aggctcagca gtaaacccat
     9961 catatttttt tccatgcgta cggcctggaa caactcgcct ttacgatcac gccagtcctg
    10021 ccatttgctg ccttcaggca gtttttgctg acttaatgag tcgactttca gcggctcatc
    10081 cagccacaaa cgccagccgg taatattgcc tgccggataa cgcatcagac gcgaggcatc
    10141 ctcaatattc accagcattt cattgccatc gacttcactg ttggcggcga aagtgccaat
    10201 cacattgaac aggcgctgac ttggaatacg ccccatcggc gtgaactggc tggcagatgg
    10261 taccatcatg cggatttgat caccgcgatt aacgcctagc tgtgaggcaa gttgttcgcc
    10321 gaggatgaca ttatatttcc ccggctcgag gtcagtttgt ttcacattga ccagatacgg
    10381 cgttagtgga tctttttgcg ccgggtcgat accgagcatc accccgaccg ccacgctgcg
    10441 cgcgctttgc agtaccacat caccggtagt aataggtgcg acgcgattaa cgccgtccag
    10501 tttgactgcc gtttccggga gttgctgcgg gttaagagag ccatgctcag aagagagaat
    10561 tgcctgtggc atcaggccaa ggatgttgtt ttgcagctcg cgctcaaagc cgttcatcac
    10621 tgacaatact gtgaccagcg ccatcacccc gagggtaatg ccgatggtag aaagccagga
    10681 gacgaaacga ccgaagcgat ccgctgcacg cccacgcatg taacgcaggc caataaatag
    10741 agcgacaggt tggtacatga aatccgtctg gttgctgtag caaagacacg agtatataag
    10801 cgaaagcaag atgggtaaac gtctgaactg taagtgatcg tcagggctaa tctgaaaagc
    10861 ccccgtaaat caatcggcta aattgccatg ttttatcatc aatcttgccg cctgatctta
    10921 atctgaaaaa tcatccaata cagacagata cccattacac ctcgggtcat aacccgcagg
    10981 atcaaccgca tgtaaattaa aaaagagcgt gttgtcctga tgaaacaaaa agagctatgg
    11041 attaaccaga tcaaagggtt atgtatttgt ctggtggtga tttatcactc ggtcattacc
    11101 ttttatccgc atctgaccac ttttcagcat ccgttatcgg aagtcctgag caaatgctgg
    11161 atctatttca atctttacct tgcccccttt cgtatgccgg tttttttctt tatttccggc
    11221 tatttgattc gccgctatat cgacagcgta ccgtggggaa attgtctcga taaacggatc
    11281 tggaacatct tctgggtgct ggcgctttgg ggcgtggtgc agtggctggc gttaagtgcg
    11341 ctgaaccagt ggctggcacc tgagcgcgat ttaagcaatg cctccaatgc cgcttatgcc
    11401 gattccaccg gtgagttcct gcacgggatg atcaccgcca gcaccagctt gtggtatctg
    11461 tatgcgttaa ttgtctattt cgtggtatgt aaaattttta gccgtctggc gctgccacta
    11521 ttcgccttgt ttgtactgtt gagtgtggcg gttaatttcg ttcccacgcc gtggtgggga
    11581 atgaacagtg tgatccgcaa tttgccttat tacagccttg gcgcatggtt tggcgcaaca
    11641 ataatgacct gtgttaaaga ggtgccgttg cgccgccatc tgctgatggc ttctttgctt
    11701 accgttctgg cggtcggtgc ctggttgttt actatctcgc tgctgttgtc gctggtatcg
    11761 attgtggtga tcatgaagct gttttatcaa tacgagcaac gattcggtat gcgctccacc
    11821 agcctgctga atgtgattgg ctccaacacc attgctatct acaccaccca tcgcattctg
    11881 gttgaaatat tcagcttaac tctgcttgcg caaatgaacg cagcacgctg gtcgccgcaa
    11941 gtcgaactga cactcctgct ggtttatccc tttgtcagtt tgttcatctg tactgttgcg
    12001 ggcttgctgg taagaaaact ttcacagcgt gcattcagcg atctgttgtt caccccgcct
    12061 tcactgcccg ctgccgtcag ttactcccgc taagccatcg ccccagccgg ggcgattcaa
    12121 tttgctaaac catgtcgatt acggataatg aacagcattg cttatcagag atatgccccc
    12181 atatgttgag gcatatccta acgagaatct gacaaccgtt atgcctgaac aatatcgtta
    12241 tacgctgccc gtcaaagcgg gtgagcagcg tctgctgggc gagttaaccg gcgcagcctg
    12301 tgcaacgctg gtagcggaaa ttgccgaacg tcacgccggt ccggtggtac tcattgcacc
    12361 agatatgcaa aatgctctgc gtttgcatga tgaaatcagt cagttcaccg atcagatggt
    12421 gatgaatctg gcggactggg aaactcttcc ctacgacagt ttttcgcctc atcaggacat
    12481 tatctcctcg cgcctttcca ccctttacca gctaccgacg atgcagcgtg gcgtactgat
    12541 tgttccggtg aatacgctta tgcagcgcgt ttgcccacac agttttctcc acggtcatgc
    12601 gctggtgatg aaaaaaggtc agcgcctgtc acgagatgca ttacgaaccc aactggacag
    12661 cgccggttat cgccatgttg accaggtgat ggagcacggc gaatacgcca cgcgcggcgc
    12721 gttgctggat ctcttcccga tggggagtga gctgccttat cgtcttgatt tctttgatga
    12781 tgaaatcgac agcctgcggg tgtttgacgt cgacagccag cgcacgctgg aggaagtaga
    12841 agcgaccaat ctgctgcccg cgcacgaatt tccgaccgat aaagcggcaa ttgaactgtt
    12901 ccgcagccag tggcgcgata tcttcgaagt gaagcgcgat ccggaacata tttaccagca
    12961 agtgagtaaa ggcacattac ctgccgggat cgagtactgg cagccattgt tcttcagcga
    13021 accactgccg ccgctgttca gttatttccc tgccaatacc ttgctcgtga atactggcga
    13081 tctggaaacc agtgccgaac gtttccagac tgacacgctg gcgcgttttg agaatcgcgg
    13141 cgtcgatccg atgcgcccgc tgttgccacc acaatcgctc tggctgcggg tggacgagct
    13201 cttctcagag ctgaaaaact ggccccgggt gcagctaaaa actgaacatt taccgacaaa
    13261 agccgcgaat gccaatttag gtttccagaa actgccagac ctggccgttc aggcacaaca
    13321 aaaagcgccg ctggatgcgc tgcgtaagtt cctcgagact ttcgacggtc cggtggtgtt
    13381 ctcggtagaa agtgaaggtc gccgtgaagc gctgggtgaa ctgctcgcac gaattaaaat
    13441 tgctccgcaa cgcattatgc gtcttgatga agccagcgac cgtgggcgtt atctgatgat
    13501 tggcgctgcc gaacatggtt ttgtcgataa ggtgcgtaat ctggcgctga tctgcgaaag
    13561 cgatctgctc ggtgaacgtg ttgcccgccg tcgtcaggat tctcgccgca ccatcaaccc
    13621 cgatacactg atccgtaacc ttgcggagct gcatattggt cagccggtgg tccatctgga
    13681 gcacggtgtc gggcgctatg ccggaatgac cacgctcgaa gcgggcggca ttactggcga
    13741 gtatttgatg ctcacctatg ccaacgacgc caaactgtat gttccggtgt cgtcactgca
    13801 tctgattagc cgttacgcag gtggcgcgga agaaaacgcc ccgctgcata aacttggcgg
    13861 cgatgcgtgg tcacgcgcgc ggcagaaagc ggcggaaaaa gtgcgtgatg tggcggcgga
    13921 attgctggat atctacgcgc aacgcgccgc caaagagggc ttcgcgttta aacacgatcg
    13981 tgagcagtat cagttgttct gcgacagctt cccgtttgaa accacgccgg atcaggcgca
    14041 ggccattaat gcggtactta gcgacatgtg tcagccgctg gcaatggatc gtctggtgtg
    14101 cggcgatgtt ggctttggta aaacagaagt ggcgatgcgc gccgctttcc tggcagtaga
    14161 taaccacaag caggtggcgg tgttggtgcc taccaccctt ctcgcgcagc agcattacga
    14221 caacttccgc gaccgtttcg ccaactggcc ggtacgtatc gaaatgatct cccgtttccg
    14281 cagcgccaaa gagcagacgc aaatccttgc ggaagtggcg gaagggaaaa tcgatattct
    14341 gatcggtacg cacaaactgc tgcaaagtga cgtcaagttt aaagatttag gcctgctgat
    14401 tgtcgatgaa gaacaccgct tcggggtgcg tcataaagag cgcattaaag cgatgcgcgc
    14461 gaacgtggat attctgacgc ttactgcaac gccgatccca cgcacgctga atatggcaat
    14521 gagcggaatg cgtgacctgt cgattatcgc cacgccgccc gcccgtcgtc tggcagttaa
    14581 aacctttgtc cgtgagtatg acagcctggt ggtccgggag gcgatcctgc gtgaaatttt
    14641 gcgcgggggg caggtttatt atctctacaa tgatgtggaa aacatccaga aagctgccga
    14701 acggctggca gaactggtgc ctgaagcacg gattgccatc ggtcacgggc agatgcgcga
    14761 gcgcgaactg gaacgggtga tgaatgattt ccatcatcaa cgtttcaacg tgctggtttg
    14821 taccaccatt atcgaaaccg ggatcgacat cccgacagcc aacaccatta tcattgaacg
    14881 tgcggatcac ttcggtctgg cgcagctgca ccagttacgc ggtcgcgtcg gacgttcgca
    14941 tcatcaggca tatgcatggt tgctgacacc gcatccaaaa gcgatgacta ccgatgcaca
    15001 aaaacgtctt gaagcgattg cctcgctgga agatctcggg gcaggttttg cgctggcaac
    15061 gcacgatctg gagattcgcg gcgcgggtga actgcttggc gaagaacaaa gcggctcaat
    15121 ggaaaccatc ggtttctcgc tgtatatgga gttgctggaa aacgccgtcg atgcactgaa
    15181 agccggacgc gagccgtcgc tggaagatct caccagccag caaacagaag tcgagctgcg
    15241 gatgccgtcg ctattgccag atgatttcat ccctgacgtg aacacgcgtc tgtcgttcta
    15301 caaacgtatt gccagcgcca aaacggaaaa cgaactggaa gagatcaaag tcgagcttat
    15361 cgatcgcttc ggcctgctgc cggatccggc gcgtaccctg ctggatgttg cccgtctgcg
    15421 ccagcaagcg cagaaactgg ggatcaggaa gctggaaggt aatgagaaag gcggggtgat
    15481 cgaatttgcc gagaagaatc acgttaatcc ggcctggttg attggtttgc tgcaaaaaca
    15541 gccgcagcat taccgccttg atggtccgac gcgcctgaaa tttattcagg atttgagtga
    15601 gcggaaaacg cgtatcgaat gggtacgcca gtttatgcgt gaactggaag agaacgcgat
    15661 cgcttaatgg taaatcgggg gcgtttctgc gcccccatct gcaacattta caaattcttt
    15721 gcacttccct gcactatccg acactgtcac catccataat tcaggcttat ctgtttatta
    15781 caataacctt atatttatta tggatttttg gtgatgatca aaacgcgttt ttctcgctgg
    15841 ctaacgtttt ttacgttcgc cgctgccgtg gcgctggcgc taccggcaaa agccaacacc
    15901 tggccgctgc cgccagcggg cagtcgtctg gttggcgaaa acaaatttca tgtggtggaa
    15961 aatgacggtg gttctctgga agccatcgcc aaaaaatata acgtcggctt tctcgctctg
    16021 ttacaggcta accctggcgt tgatccttac gtaccgcgcg cgggtagcgt gttaacgatc
    16081 ccgttgcaaa ccctacttcc agatgcgccg cgcgaaggca ttgtgatcaa tattgcggag
    16141 ctgcgtctct attactaccc gccgggtaaa aattcggtaa ccgtgtatcc aataggtatt
    16201 ggtcagttag gtggtgacac gctgacaccg acaatggtga ccaccgtttc agacaaacgt
    16261 gcaaacccaa cctggacgcc aacggcaaac atccgcgccc gttataaagc acagggaatt
    16321 gagttgcctg cggtagtgcc ggctggaccg gataacccaa tgggccatca tgcgattcgt
    16381 ctggcggcct atggcggcgt ttatttgctt cacggtacga acgccgattt cggcattggc
    16441 atgcgggtaa gttctggctg tattcgtctg cgggatgacg atatcaaaac actctttagc
    16501 caggtcaccc caggcaccaa agtgaatatc atcaacactc cgataaaagt ctctgccgaa
    16561 ccaaacggtg cgcgtctggt tgaagtacat cagccgctgt cagagaagat tgatgacgat
    16621 ccgcagctgc tgccaattac gctgaatagc gcaatgcaat catttaaaga tgcagcacaa
    16681 actgacgctg aagtgatgca acatgtgatg gatgtccgtt ccgggatgcc ggtggatgtc
    16741 cgccgtcatc aagtgagccc acaaactctg taaatcctgg ataaaaaaaa tccccgcgac
    16801 acggcatgtc gcggggaaaa aatcagcagt agcaggcatt aatgagggtt aatgcttatt
    16861 tataaattac tgctgttcca tggagggtat tcggaccggt tacagaagta atacggaaag
    16921 attttgcgcc catctcatcc gctttttgcg ccagctgctc ttccagcgat cccagatttg
    16981 tccccgcgtt agcactgatt gtaccgactt tttgttggcc ttctggcgtt gactgaactt
    17041 cgacagccgc aaagctggca aatgacatgg agcttaaaat cgccgcagcg atgagggttt
    17101 ttacgttttt cataatagtg gccttatgca gatgaatgac gtcgcaagca attacttaac
    17161 gatcgataac taaatgatag atgtgatctg gatcacatac aagatatttt ttataacaat
    17221 cattaattaa tttaaaaatc tttaaatttc agttaaatag aaagcaatta tttttatggg
    17281 atctggactg gtgaacggag gtgattattt ttataataac ctttcattca cagtcaccag
    17341 gtacaacggc atcatggcaa ctgactcaac acaatgtgta aaaaaaagcc gtggccgccc
    17401 aaaagtgttc gacagggatg ccgcgcttga taaggccatg aaattgttct ggcaacacgg
    17461 ttatgaagcg acttctcttg cggacctcgt cgaagcgacc ggagccaaag cgcccacgct
    17521 atacgcggaa tttaccaaca aagaggggtt atttcgtgcc gttctcgacc gctatatcga
    17581 tcgttttgcc gctaagcatg aagcacagct gttttgtgaa gagaaaagcg tggagtctgc
    17641 gctggctgac tattttgctg ccatcgccaa ctgctttacc agcaaagaca ccccggcagg
    17701 ctgcttcatg atcaacaact gcaccaccct ctccccagat tcaggagata tcgccaatac
    17761 gttgaaatca cgccatgcga tgcaagagcg cactttgcag cagtttttat gtcaacgaca
    17821 agcgcgcggg gaaatcccga cccactgtga cgtgacacat ctggcagaat tccttaattg
    17881 tattattcag gggatgtcga tcagcgcacg cgaaggtgca tcgctggaaa aactaatgca
    17941 gattgccgga acgactttgc gtttatggcc cgaactggtg aaataagtcg caaaaaaagc
    18001 ccctcagcct gagcgaatga ggggccaaat tgcagagtac agccttgtta tactttgtta
    18061 ttcaaaatca gttgcccatt actatctagc gggatctgcg tacccggatc gcggtccatg
    18121 cggattttgc cctgctgatc gccaatctta taggtcacat cataaccgag cattttttct
    18181 gacttgtcat acaccgtttt acaacgctgt tgcgtagtcg tgtaagtatc gctttcctgg
    18241 agagagccct ggatctggtt accggcatat ccaccaccca gcgcccccac aacagtggcg
    18301 acatctttac cgcgaccacc gccaaactga tgccctatca cgccgccagc aacagcgccg
    18361 agcaccgacc cggtaatgcg attttcatcc tgcaccggtc gacgatgggt cactgtgacg
    18421 ttgcgacact cctgacgcgg tgttttaacc gtttccttga ttggggttgc agaaacaacc
    18481 tgagcgtatt gcgggccacg ttcaaacacg ttcagactgg ccactgccgc tacgcccagc
    18541 gcagctgcga caccaatccc gatacccgcc aacattgatt tattcacggg aacacctcct
    18601 tctttgcagt tatgccaatc atgcaagcga aggagaaaag cagctatcag acagaagatg
    18661 aaaagcgcgg gaatggctgg aaatacttaa ggattcggag gagtctgaag gaatgcctga
    18721 tgcgacgcgg ctgccgatcg cgctgttcct caagggcgga taaggcgttt atgccacatc
    18781 cgccagtgta cgtcgattaa tgcaacttca aacgcggacg gataacgcgg ttaatactcc
    18841 ccaccagcat cattaatccg gttttaaagt aaccatgcag cgcaatctga tgcattcggt
    18901 atagcgagat atatacaaag cgcgcaattc gtccttcaat catcattgag ccgcgcgtca
    18961 ggttacccat caggctacca acggtggaga agttcgacag cgataccagc gaaccatgat
    19021 ctttatactg ataatttttc agcggcttac cattcatctg cgccagaatg ttgttcattg
    19081 cgcaagtcgc catctggtgt gcagcctgag cacgcggcgg aacaaagccc ccttccggac
    19141 gcgggcatga cgcgcagtcg ccaatagcgt aaatgtctgg atcgcgggtg gtttgcagcg
    19201 tcggttccac caccagctgg ttgatacggt tagtttcaag accaccgata tctttcagga
    19261 agtctggcgc tttgatcccg gctgcccaca ccatcagatc agcctcaata tattcgccat
    19321 ctttagtgtg caggccgcct ttatcagcac tggtgaccat ggtttgcgtc agcacgcgaa
    19381 cgccaagttt cgttagctcg ttgtgggccg cagcagagat acgtggcggt aatgcaggca
    19441 aaatacgttc tcccgcttct accagcgtta cgttcagggc ttcgttggtc aggcctttgt
    19501 aaccgtagct gtgcagttgc ttgaccgcgt tgtgcaattc agcggagagt tctacacccg
    19561 tcgcgccgcc gccgacaatc gcaatgttca ctttgccatt tgcgcccagg ttggcggagt
    19621 atttcaggaa gagattcagc atctcctggt gaaagcgacg cgcctggtgc gggttatcga
    19681 ggaaaatgca gttctctttg acacctggcg tattgaaatc gttagaggtg ctacccagcg
    19741 ccattaccag ggtgtcatag gcgattttac gttccggaac tagcagttca cctttctcat
    19801 cgcgcagttc tgcaatagtg attgttttcg cttcacgatc aatatcaatg acggaaccca
    19861 gctggaactg gaaaccatga ttgcgcgcat gggccagata gctcaacgca tcgacgcctt
    19921 catcaagcga gccagtcgcc acttcgtgca gcagcggttt ccacagatgg ctgtggttac
    19981 gatcgaccag cgtaattttg gcttttttct tgcgtcccag cttatgcccc agctgtgttg
    20041 ccatttccag cccaccagca ccgccgccga caatcacaat ctttttcaat ggcgtagtca
    20101 acgtgacccc cttaaattta ttaaccaatt gttaattaat ggttattaac atagctctta
    20161 attaacaaca ggttacagca atgaaaatgt tcttcgctat tgagaataac atgaatggtg
    20221 cattggtcat accaaaattg atgttaatca agttttgttg ctgaaaagat aggcgacttt
    20281 accgggtgag atcaaaaaac agagtttatt gtttattatt tgagcaagcc cggaagggcg
    20341 atatagggtg aagcgtatat cgagggcgtt tggtcgtcct gataagaggc gcatcaggca
    20401 ttgatgctcg aatgtcggat gcggcgtgaa cgccttatcc gacccacaga atccggagcg
    20461 catcaggtac cggcaaggtt acctgatgcg acgagggcat ttacccgagg gttttgaacg
    20521 ctttaatgcg ctgtaaatgc ggggagatat tcttgaattt gtgcgtctgc tcttcgtccc
    20581 agacaatctc gtaataatga tgcagctctt cagatgtccg ctggctgtta agcgcttcat
    20641 cattacgcga caaaatcacc aggcaacgat cgcgattctt ctcacggaag ttggtcacac
    20701 acttagtggc aatatcggca tactcttccg ggcgatcaat cttgccttcc atgttctcat
    20761 tagggaacaa attagggttg aagatcacct ggcggatatc gcaaagaaaa ccaatccgtt
    20821 ccgcccagta tccgcccaga ccaacgccgc aaatcagcgg acgctcgtcg acgttcagtt
    20881 gcaacatttt gtccacttct ttgagcagat gctgcatatc atgtttcgga tgccgcgtac
    20941 tgtagcttat caagcgtaca tccgggtcaa taaactgcaa ttgtaagact ttctcgtggt
    21001 tacccggact gttagagtca aaaccgtgta aatagataat catcgcttcc tcacataagc
    21061 cagggttagt gacctgcttt ctcttcctgc cagcgttcat gtaactgatt cagacgggtg
    21121 ctgatcgctt tccagcgagc cgagtccatc agttcctgtc gcgaaaatga acctttatga
    21181 tacaaacgtg taacacgttc tgccttgatc ggtgacagat tatctaacac gctgacggcc
    21241 cctttacgat tattgcagac caggatcata tcgcaacccg catccagtga tgcctgcccg
    21301 cgttcggcat aactgcccat aatcgcggca ccttccatcg ataaatcgtc agagaaaatc
    21361 acgccgtcaa aacccagttc ctgacgcaaa acggttttca gccagtaggg agaaccgctc
    21421 gccggacgcg gatcaacatc actgtagatc acatgcgcag gcataatggc gtcgagttta
    21481 ttttcgcgga ttaaggaact gaagaccgac atatctttag cgcgaatctc cgcttgtgga
    21541 cgtggatcgc acggtgtttc tttgtgtgag tctgccgtta ctgcaccgtg tcctgggaag
    21601 tgtttcccgg tcgttttcat tccggcttca tgcataccat caataaaccg gctggcaatt
    21661 gccagggctt tttgtggatc ggcatgataa gaacgctcgc caatcgccgc gctgatatgc
    21721 ccgacatcca gcacaggcgc aaagctgata tcaatatcca tagcgatcat ttcgctggcc
    21781 atcagccaac ccgcctcttg cgccagtttg ccgccctctt ccattcccaa cagcgcagca
    21841 aaggattgtg ctgccggtaa gcgggtaaaa ccttcgcgaa aacgctgcac gcgtccacct
    21901 tcctgatcta ccgccaccac cagatgattg cgcgaagctg cgcggatctg gcgcaccagt
    21961 tcacgcaact gggcaggatc atgatagtta cgcttaaaga gaatcagccc tcccaccagc
    22021 ggatgcgcaa gtatttcacg ctcttccgcg tccagttcgt aaccttcgac atccaacatt
    22081 actggaccca cactgctctc cttattgttt tattaatagc tgccgccagg tgtcatcggc
    22141 cagcctgata aattgttgat cgccggtttg tcgccagcgg tactcaaacc accctgcttt
    22201 gagcatcagc agccagggaa accatcgcct gacctgacgc cataattgcg ccggataaat
    22261 cttcgcgcga gtggcatagt cattgaccaa ttgccggtgc tggtcagtat tttccaccca
    22321 caccgccgcc agttccagcg cgatatcacc atctccggca tactcccagt cgatgagttt
    22381 taaccctgac gcgctatgca ctaaatttcc ggcgtggaca tccatatgca atggacttaa
    22441 gcgtaaaggc cgtggttccc gcgctttgcg cagacgtttt aaccttcgca gccaacccac
    22501 tgtccgccgc gccggatcgc tttgctgcca gtacagttcc agtaacggca acagcgttat
    22561 tcgccagcca aaacgcggtt gttgatgtag ataatacagc aagcctgcca gttcgttggt
    22621 atccggcaaa tacgttttta cctcgccggg cagatagtcg accaccatcc agtcacggag
    22681 atataaatgc ggcttcggtg caatacatgc gggtaattgt gataaagccc gatactggcg
    22741 caagaacgcg aaccgcggcg catcaggatc gtgcggctga cgtacaacaa aacgctggcc
    22801 ctggtgttca atgagaaaac tcccgccact aagcccacta tgaaacgtcg tgacgggatg
    22861 aaactgcggg aaaaagcgcg acagcaattc gtcgcgcatg atgggattat tgctgcgaaa
    22921 cggcaccttt acctgaccag ataatttcgc ccgtctgcac cagcatcagc tgcatttgta
    22981 gggtcggagc gttaacgttg ccagaggcgc tggagtacag cacgtaatga gcgccgacat
    23041 tgcgggcaat gcctatggct ttactacgag tacctaaact gtcctgcggc gacaaaccta
    23101 actgttgctt agccatcgac agctgctggg cggaaaccag ggtaaatttc ccgttattag
    23161 ccagcgcatt tcgcagcgtt tcggtcgctt ctgcggcatt cagcgaaccg ttagtacggt
    23221 tgttaacgct atcaaccagc aggacgctac ccgcagtcac cccgtcagcc ccaagcatct
    23281 tactgaccat cggctgcatt gcgccattcc agtcataatg gcgaatatgc ggcgcaggcg
    23341 gtgccgtttg atcttcgtgc tcaattgggc ctggctgctg cgggatcgtc ggcaccgagg
    23401 gcactgtggg gacaggctgt tgtggctcgg ctggttgttc cggcgctggt ttcacttctt
    23461 ctaccggtgc aggttcacgt tgccccacac acccggcgag aaacatcgcc agcgcggtaa
    23521 tcaaggcgta gcgactcatt tttgtcatca agattcaccc cttacaaata tagataaagt
    23581 ctgactttgt gcgcccccag aaaattggcg ctgccgtaca gcgttaccgc cgaatgtgcg
    23641 ggaatgctaa cgctgcgtgg cctttccaga ggatgcatct ccagccctct ggcgtcatac
    23701 cagtaaaaac gataatgaac ggtaacgggt tcttgccttt cgttataaag cgttgaggat
    23761 gctgaaggtt gaatatcaga cgtcgaaagg acgggctttt ctgcactgat gcccgcagcc
    23821 aataaagatg actccatcac cagcgattgc tcatcattca ccggaatttc cggatgtgaa
    23881 cgacagccca ccagcagtaa caacgccaga gacaccagcc caaagcatcc ttttctcatc
    23941 gttacagacc tttatgcgcc agcattggtc ccagcggacg gccacccaac aagtgcatat
    24001 ggatgtggta aacctcttgt ccgccatggc ggttggtatt catgatcaga cgatagccat
    24061 cttcggcaat accttcttgc tcagcaattt ttgccgctac ggtgatcatg cgtcccagcg
    24121 cctgctcatg ctcagctgag acgtcgttca cagtcggaat gaggatattc ggaatgatca
    24181 gaatatgcgt tggcgcttgc ggcgaaatat cgcgaaacgc cgttaccaga tcatcctggt
    24241 agacgatatc ggaggggatc tcacgacgaa taattttgct gaatatagtt tcttctgcca
    24301 cgacattttc ctttttcaaa tagccatgcg ttgcgccatg ctacgccgcg ccacactgcg
    24361 agtatagagt atggtcgagt taaacctgct ctttcaacct taactcacga tttcttaagc
    24421 aaaaaatcgt tttgctgccg tatatatcgc cattattccc atttctgcct gcgaatgcgc
    24481 tgaaaagaca ttctctgttt ggtttacacg acaaatatga atgcgtatat ttctcatttg
    24541 catttacaaa caaaattatt cgcacactaa atataatcgc tcatcaccct cctccggcat
    24601 gagcctgacg acaacataaa ccaagggatt tcaaatgctt tcaacacaat ttaacaggga
    24661 taatcaatat caagccatca ccaaaccgtc actacttgcc ggttgcatag cactggcact
    24721 attaccttct gccgcttttg ctgcaccagc cactgaagaa acggtgattg ttgagggttc
    24781 agccacagct ccagatgatg gcgaaaatga ttacagcgta acgtctacct ctgcgggtac
    24841 caaaatgcag atgactcaac gtgatattcc tcagtcggtc actattgtta gccagcagcg
    24901 gatggaagat cagcagttac aaacgctggg cgaagtgatg gaaaacacgc tggggatcag
    24961 caaaagtcag gcggattccg atcgtgctct ttattattcc cgcggattcc agatcgataa
    25021 ctatatggtt gatggtatcc ccacctattt tgaatcgcgc tggaatctgg gcgacgcact
    25081 ttctgatatg gcactctttg aacgcgtaga agtagtgcgt ggcgcgacag gactcatgac
    25141 cgggacgggt aatccatctg cggcaattaa tatggttcga aaacacgcga ccagtcgtga
    25201 atttaaaggc gatgtctcgg cggaatacgg tagctggaac aaagaacggt atgtggcgga
    25261 tttacaaagc ccactcaccg aagacggtaa aatccgcgcg cgaattgtcg gcggctacca
    25321 gaataacgac tcatggctgg accgctacaa cagtgaaaag accttcttct ccggcattgt
    25381 cgatgctgat ttaggcgatc ttacgacgct ttcagccggt tacgaatatc agcgcattga
    25441 tgttaatagc ccaacctggg gcggtttacc gcgctggaat actgatggca gcagcaacag
    25501 ttacgatcgc gcacgcagta ccgcacctga ctgggcgtac aacgataaag agatcaacaa
    25561 ggtctttatg accctgaagc agcggtttgc tgatacctgg caagcgacgc tgaatgccac
    25621 ccactctgaa gtcgaatttg acagcaaaat gatgtatgtc gatgcctatg taaacaaagc
    25681 ggatggtatg ctggttgggc catacagtaa ttatggacct ggctttgatt atgtcggcgg
    25741 caccggttgg aacagtggca aacgtaaagt tgatgcgctg gatttgttcg ctgacggtag
    25801 ttatgaattg tttggtcgtc agcacaatct aatgtttggt ggcagttaca gcaaacaaaa
    25861 caatcgttac ttcagttcat gggccaacat cttcccggat gaaattggca gtttctacaa
    25921 ctttaatggc aatttcccac aaaccgactg gtcaccacag agcctggcgc aggacgatac
    25981 cacacatatg aaatcgttat atgctgccac tcgtgtcacc cttgccgatc cgctgcatct
    26041 gatcctcggc gcacgttata ccaactggcg ggttgatacg ctgacttaca gcatggagaa
    26101 aaaccacacc acgccttacg ctggtctggt gtttgacatc aatgacaact ggtcgaccta
    26161 cgccagctat acctctattt tccagccgca aaatgatcgt gacagttcag gcaaatatct
    26221 ggctccaatc accggtaaca actacgagct gggtctgaaa tcggactgga tgaatagccg
    26281 tctgaccacc acgttagcca tcttccgtat tgagcaggat aatgtcgctc agtccaccgg
    26341 tacacctatc cccggcagca acggcgaaac cgcctataaa gcagtggatg ggacagtcag
    26401 taaaggggtg gaatttgaac tcaacggcgc aattaccgac aactggcagc tgacatttgg
    26461 cgcaacgcgc tatattgcag aggataacga aggaaacgcc gttaatccta atctgccacg
    26521 caccacggtt aaaatgttca ccagctatcg gttgcctgtc atgccagagt tgacagtcgg
    26581 cggtggtgtt aactggcaaa atcgcgtgta taccgacacc gtgacaccgt atggcacctt
    26641 ccgcgccgag caaggtagct acgcgctggt ggatctcttc acccgctacc aggtgacgaa
    26701 aaacttctcg ttacagggga acgtcaataa cctgttcgac aaaacctacg ataccaacgt
    26761 ggaaggttct atcgtctacg gcgcaccgcg taatttcagc attaccggca cgtatcaatt
    26821 ctgaataaca cctgtaaaaa aggcagccat ctggctgcct tagtctcccc aacgtcttac
    26881 agattagtgg ttacggatgt actcatccat ctcggttttc aggttgtcgg atttagtacc
    26941 gaaaatcgcc tgaacaccag aaccagcaac cactacgccc gctgcgccca gtttcttcag
    27001 gccagcctga tccactttag acacatcagc aacgctgacg cgcagacggg taatacatgc
    27061 gtcgaggtta gtaatgtttt ctttaccacc aaatgcagca accagagccg gtgccatttc
    27121 gctggtacct gtcgcttttg catcttcagt cgcgtcttca cgacccggcg ttttcagatc
    27181 cagtgcttta atcagcacgc ggaagatggt gtagtaaaca atcgcataac cgataccgac
    27241 gatcgggaac agccacagtt tgctgctgtt accagacaga acgatgaagt cgatcagacc
    27301 gtgcgagaac gacgtaccgt cacgcatccc cagaagaata cagattggga atgccaggcc
    27361 tgccagaatc gcgtggatga tgtacaggat cggcgcaacg aacatgaagg agaactcgat
    27421 cggctcggtg ataccggtca ggaacgaggt cagcgccgcg gagatcataa taccgcccac
    27481 tttcgcgcgg ttttctggtt tagcagagtg ccagatagca attgcggcag ctggcagacc
    27541 gtacattttg aacaggaagc caccagacag tttacccgca gtcgggtcac ccgccatata
    27601 acgcggaatg tcgccgtgga aaacctgacc tgctgcgttg gtgtattcac caatctgcat
    27661 ctggaaaggt acgttccaga tgtggtgcag accaaacggt accaggcaac gttcgatgaa
    27721 accgtaaatg ccaaacgcaa ctaccgggtt ctggtaagca gcccactgag agaaggtctg
    27781 gattgcagaa ccaatcggcg gccaaatgaa ggacagcaca acgccagtaa agatggcagc
    27841 caggccagaa atgatcggca caaagcgttt accggcaaag aagccaagat actcaggcag
    27901 cttaatacgg tagaaacggt taaacatgta cgctgcgatc gcaccggaga taatccctcc
    27961 gagtacgcca gtatccgcca ggtgtttaga ggcgatttct tcagcaggta aatgcagtac
    28021 cagtggcgca accacggcca tggttttaac catgatgcca taggcaacaa ctgcggccag
    28081 cgcggatacg ccatcgttat tggtaaagcc gagggcgaca ccgatcgcaa aaatcagtgg
    28141 catgtttgca aagacggaac cgcctgcttc tgccataaca tgcgatacaa cggcgggcag
    28201 ccagctgaaa ttcgcggaac cgacgcccag cagaatacct gcgataggca gtacggatac
    28261 cggcagcatc agcgatttac cgaccttttg caggttagca aatgcattct taaacataat
    28321 tgagagtgct cctgagtatg ggtgcttttt ttacgttctc acgcgtggca aggggggaga
    28381 gcctcgccgt gtacagggca tctaagcgcc ctttatttat tacacagagt aaaataattc
    28441 agtgccaatt tgtttgacgg ctatcacgtt tcaacttcag atcattggag aagttgcaca
    28501 ttttgacaaa acatatgtca caatatttca aacgtggtta ttcaccgccc aattttcggc
    28561 ggtgaacttt actcgtttta gccattaatt acgagcttta aaaaaactca ttcaacggat
    28621 ggattgaagg cgggaagcgt cgatgtgaaa cagacgggcg aagttatcgg tggttacctg
    28681 cgccagttct tcaacggcaa cacctttcaa cacagccatg tattctgcaa cgtcacgaac
    28741 catcgcaggt tgattctctt ttcctcgatg cggtaccggc gcaaggtaag gtgagtcagt
    28801 ttccaccagt aatcgatcca gggggacata acgcgcagca tcgcgcagtt gctccgcatt
    28861 acggaaggtc acaatgccgg aaaaggagat gtaaaatccg agatccagta atttacccgc
    28921 cgtttctctg tcctctgtaa aacagtgtag tacgccaccg caatccgtca ctttttcttc
    28981 gcgcagaatt gccagcgtat cggcacgggc gtcacgggta tggacgataa ccggcttgtt
    29041 cagttcacga ccaatctgga tatgatggat gaaggactct tgctgacgta ctttagtttc
    29101 cggtgtgtaa taataatcca gcccggtttc acccagcgct acaacaccct cttctgccgc
    29161 cagacggcgt aaatcttcta catcgtaggg atcattctgg ttgagtggat gcacgccaca
    29221 agaaaatacg acgttgtcac gttcgcctac cagatcccgc atatgtaaat aacccggtaa
    29281 tgttgtggcg actgccagac aaaatttcac atcgcgtgcg gcggctttcg ccagaacgtc
    29341 atccacgtcc ttatgcaaag attcataatc cagaccatcg agatggcagt gtgagtcgac
    29401 taaaaacatg atgtctctct taaagatgag gaaccggtag cacaacgccc ggttgcaggt
    29461 aatgctcaat acgcagtaaa agatcggtga tgagaagctc gcggttgatg cctgtaacag
    29521 acattaactg ttcacgaatg tggcaaacat cccccagtat agcctgcagg cgcgagggag
    29581 aaagatggtt tgccagttcg gcgaccaggc ccggcacatc aacattggtc acctgcgcag
    29641 caccatgatg gcgttttagc gcatccatca gcaacgttgc cagccagtgt aaacgcgccg
    29701 gagcttgttc atgattaagg gccgctagca gcgaatacca gtcgcccgat ggcacgctat
    29761 atgccaacgc ctgacacaat gtttcacgag cctgccagtt atctccctga aacaacgcca
    29821 gtgccgcgcc aggcgaaccg gcgcttaagc gcaatgcggc aagtaatgca tcctgtgaca
    29881 ttgtcacttc gcgtgaaagc caggtcacgg cgtactgttc cggcggcggc gcaaggtaat
    29941 gtaaccgaca acgactacgt aatgttgcca gtaaacgttc aggctcgcgg gtagccagga
    30001 aaaaccaggt ttctgctggt ggctcttcaa gcgttttcag caatgcgtta gccgcggcgt
    30061 cggttagtaa ggcagcatcg gttacccaga caactttcgc accacctaag cgtgcgtgct
    30121 cattcagctt ttcggtgacc tcacgtaccg catcaatgcc caacgcattt ttcccttttt
    30181 cgggagccag ggtgtagtaa tcgggatgcg tgccagcctg catcaactga catccacgac
    30241 agtgaccgca acttttgtgg ccctgcggtt gttggcagag taaataacgg ctcagggcgt
    30301 agattaaagc atcatcgccc atgcccggta acgcctgaat gagtagcgca tggtgacctc
    30361 ttccggcctg atagctggct accagttttt cgaaatcagg tcgtaaccat ggataccatc
    30421 tcatgcgtcc aactccttaa cccagtgggt cacggtagtg cggattgcat ccatcacggc
    30481 ctccagcggc tgggtggcat caatggtatg aatactttta tcttgtgcag ccagttccag
    30541 atagcgggcg cgggtgcgat taaagaaatc gaaagactct tgctcaatac gatccagctc
    30601 gccgcgcgca cgcgcgcgtt ttaagccaac ttccggggta acatcgagat agagcgttaa
    30661 gtcggggcga aaatccccga gaacagcatc acgcagtgtt gccagcatat gttggtcaat
    30721 accacgtcct ccgccctgat acgcctgagt ggagagatcg tggcgatcgc caatcaccca
    30781 ggtgccgtta gccagagctg gtttgatgac cgtttctacc agttgaacgc gcgcggcata
    30841 aaacatcaga acttcggctt tatcggtaat gacttcatcg cctaccgatt tgatatccag
    30901 caccaggctt cttaactttt cggcaagttg cgtaccgcca ggttcccgag tgaaaaccat
    30961 gtcgcggata cccagttgct caagcgtctc aaccaccaca ttacgcgcgg tagttttgcc
    31021 tgcgccttcc agcccctcaa tgacgatata cttactgcgc atttttttcc ttaagcactt
    31081 tcagataatc ctgcacagac ttgttatggc tggcaagatt ggtattaaac gtgtgaccac
    31141 ctttaccatc ggccacaaaa tagagatacg gcgtttttgc cggatgcgca gcagccttca
    31201 gcgaatccgc ccccggcgta gctatcgcac ccggcggcaa accggtaatg gtataggtgt
    31261 tatacgctgt cggcgtttcc aggtctgcac gagaaagttt gccattataa cgctctccca
    31321 tcccgtaaat cacggttggg tcggtctgca ggcgcatacc aatgcgtaaa cggttgataa
    31381 ataccgaggc aacctgatcg cgttcactgg caacggcggt ttctttttcg ataattgatg
    31441 ccatcgtcac cagctgattt ttatctttat aaggcagacc gtccgcacgc ccttcccagg
    31501 cgctatcgac cgctttcacc attttcttgt gcgctcgctt gagtaacgcg acatcggtgg
    31561 tattggcggt atacatccag gtgtctggcc agaaccaacc ttcaatccac tccgggtttt
    31621 ccagttcaag tgcctgcgct acggtggcgt acttatcgtc actcagcgtg tgcttgatat
    31681 acggagcctc acgcaattgc ttgaggtagt cgctcagacg catcccttct accagtcgca
    31741 gcgggaactg tgcttcttta ccgctttcca acaatttcag catctcgcgc acggtcatct
    31801 gcggtgtaaa gcggtaagtc ccggctttaa agtgagaaag atccggttcg atacgcagca
    31861 gccattgaaa aacccgtggg cgattgatga tcttatcagc ataaagctgt tcaccgagcg
    31921 ccagacgtcc ggtccctggc ttcagggtaa atatcgtctc ttctttgata agcaatttgc
    31981 tgtcggcaag atggcgaacc ttccagacgc ccacaccagc ggcgataccc agtaccacca
    32041 gcaataacaa gattatcaat aacacttttt tcatgactaa ttcgggcgct cacaaagtgg
    32101 ggctaaatat tcatataacg ttgctgacga aaaggagaca tcgccacagg cacgtacggg
    32161 catcactggc attaacgcat tacaaataac catctcatct gcctgcaacg cctcttccag
    32221 agaagcttgc acttcgacaa gctgataaga ggattgtgcc agcaaacgga tacagaattg
    32281 tcgcataatg ccgttaacac ctgcctgatc cagtcgcggc gtataaacta cgttgccctt
    32341 ccgccagaac aaattagccg cacagcattc cgtaacccac ccttcgctgt caaggaccag
    32401 cgcctcatca gcgtttgtct gctcaagatg agagcgaatc aatacttgct caagacgatt
    32461 gagatgttta atacctgcaa gatgaggatt gcgccccagc cgcaccgggc ttagcgccaa
    32521 cgtcatcccc tcgttacgca aacggtcgta atgtgcagga taagccgtaa cggagagaat
    32581 ccgcgttgcc ggtccactgt tcaatgtgct gtaccctcgc ccgccactac cgcgactgat
    32641 cacgactttc agtacaccat tttgctgttc tgctgccagc gttttcatct cttgttcaag
    32701 ctgtggccag aagtcacagg aaatcatcaa ccgctgacaa gcatcctgta gtcgctggat
    32761 atgcgccgat aacaaactga ctttaccgtc gataactctg gcggtggtaa aacaaccatc
    32821 accaaactgc gttgcccgat cgcttactgc cagcgattcc tgcttataac cgttaattaa
    32881 gaacataccg gctccttatc agagaattgt tagtgtggca gcatgttcac tacggaacaa
    32941 gtcggaataa aagctaagaa aaaaggcccg caagcggacc ttttataagg gtggaaaatg
    33001 acaacttaga tctttttaaa gatcaaagaa ccattagtgc caccgaagcc gaaggagtta
    33061 cacagcgtgt attccattcc gctgacctga cgtgcttcat gcggtacgaa atccagatcg
    33121 caaccttcat ccgggttatc caggttgatg gttggcggaa cagcctgatc gcgcagcgcc
    33181 aggatggagt agatagattc tactgcaccc gccgcaccta acagatgacc ggtcatagat
    33241 ttcgtggagc ttaccaacac acggcttgca gcttcaccga agatggtttt caccgcctgc
    33301 gcttcagctt tatcgccagc cggcgtagaa gtaccgtgcg cgttaacgta gccaatctga
    33361 ctcgcttcaa tgcctgcatc acgcagagca tttgccattg ccagagctgc gcctgcgcca
    33421 ttttctggcg gtgacgtcat atgataagca tcgctgctca taccaaagcc gacgagttca
    33481 gcgtaaattt tcgcaccgcg ttttttcgcg tgttcgtact cttcaagtac cagcataccg
    33541 gcaccatcgc ccagtacgaa gccatcacgc tctttatccc acgggcggct cgccgcttgc
    33601 gggttatcat tgcgggtaga taatgcacgt gccgcgccaa aaccaccaac acccagcggc
    33661 gtactggctt tctctgcgcc acctgcaacc atcacgtcag catcgccata cgcgataata
    33721 cgcgcagcat gaccaatgtt gtgcacgccg gaagtacagg cggtcgcgat agagatgctt
    33781 gggccacgca ggccatacat gatagtcaga tgacctgcca ccatgttcac aatcgttgac
    33841 ggaacgaaga atgggctgat cttacgtgga ccaccgttca tcagagatgt gtggttttct
    33901 tcgatcagtc cgaggccgcc aatcccggag ccaattgcgg caccaatgcg ggttgcgttc
    33961 tcttccgtta tttcaaggcc agaatcctgc atggcctgaa cgccagcgac aattccatat
    34021 tgaatgaagg catccatctt gcgctgttct ttgcgcgaga taatgtcctc acagttaaaa
    34081 tcctttacta agccagcaaa tttcgttgca taggcgctag tatcgaaatg gtcgattagg
    34141 ctgatgccac tctgaccggc aagcagagct ttccaggtag actctacggt attgccgaca
    34201 ggagacaaca tgcccagtcc ggtcacaact acacgacgct tagacacgtt tgtcctccag
    34261 ggagggaaaa aatgattcta gtgggacaaa aagataaaac tcaggcggtc gaacgaccgc
    34321 ctggagatgt tcacttacgc ctggtggccg ttgatgtaat caatggcagc ctgaacggtg
    34381 gtgattttct cagcttcttc gtccggaatc tcagtatcaa actcttcttc cagagccatt
    34441 accagctcaa cggtgtcaag agaatccgcg cccaggtctt caacgaaaga agcattgttg
    34501 gtaacttctt cctgcttaac gcccagctgt tcgccgataa ttttcttaac gcgttcttcg
    34561 atagtgctca tactcttaaa tttcctatca aaactcgctt tcgcgatggt tttcgtagtg
    34621 tataaaatgt tgaaaaattt gcaactaaat cccggcaggt cttaccacga ttttacgtta
    34681 ttttgaggcc ttacccccca ataacgcaaa tcattttgca ctaattatta ctcataacca
    34741 cgcagactgc gcgcaacatg agcattttgt gcaaatcgcg gtcagaccat gtacatcccg
    34801 ccgttcacat gcaaagtttc acccgtgatg taagctgctt cgtcggatgc caggaatgca
    34861 accgcgttgg cgatttcctg tgcgccgccg aggcgacccg caggaacctg cgccaggata
    34921 cccgcacgct ggtcatcgct cagcgcacgt gtcatgtccg tttcaataaa gcccggagca
    34981 acaacgttta cagtaatacc gcgtgacgca acttcgcgcg ccagtgattt actgaagccg
    35041 atcaagcccg ctttcgccgc agcgtagttg gcctgaccgc catttcccat ggtaccaacc
    35101 acagaaccga tagtgataat acgaccatga cgctttttca tcatagcgcg cattaccgct
    35161 tttgacagac ggaaaacaga tgaaaggttg gtttcgataa tatcgttcca ctcttcatct
    35221 ttcattcgca ttaacaggtt atcacgagtg ataccggcat tattgaccag gatatccact
    35281 tcaccaaatt ctgcgcgaat tttttccaga acagattcga tagatgccgg gtcggtcaca
    35341 ttcaacatca gacctttgcc gttagcacct aaataatcac tgatcgcctg agcgccattt
    35401 tcactggtcg cagtgccaat aactttcgcg ccacgggctg cgagcgtttc agcaattgcg
    35461 cggccaattc cgcggcttgc accggttacc agtgcgattt ttccttcaaa attcatgatt
    35521 ttcctctttt aaagctcgag cgccgctgcc atcgctgaag gttcgttcag cgccgaggcg
    35581 gtcagggtgt cgacaatgcg tttcgtcagg ccagttagca ctttgcccgg gccgacttca
    35641 tagagatgtt ctacgccttg cgctgccatg tactcaacag acttcgtcca ctgaaccggg
    35701 ttatacaact gacgtaccag tgcgtcacga atggcatcac cattggtttc gcatttcaca
    35761 tcaacgttat tcacaacagg aactgttggt gcgttaaagg tgattttcgc taattctact
    35821 gccagtttgt cggctgctgg tttcatcagc gcacagtgag acggtacgct cactggtaac
    35881 ggcagcgcgc gttttgcgcc cgcagcttta caggcagcgc cagcacgctc aaccgcttct
    35941 ttatgaccgg caataaccac ctgtcccgga gagttaaagt ttaccggaga aacgacctga
    36001 ccttctgcag cttcttcaca cgctttcgca atagacgcat catccagacc gatgattgcc
    36061 gccatagcgc cagtgccttc cggtacggct tcttgcatga acttaccgcg catctcaacc
    36121 agacgcaccg catcagcgaa atcaatcacg ccagcgcaaa ccagcgcgga gtattccccc
    36181 aggctgtgac cggccatcat tgccggtgct ttaccgccct gctgctgcca tacgcgatac
    36241 agcgcaacag atgcagtcaa cagcgctggc tgggtttgcc aggttttatt cagttcttca
    36301 gctggcccct gctgggtcag cgcccacagg tcgtagccca gcgccgcaga agcttcagca
    36361 aacgtttctt cgacaattgg atagctcgcc gccatatcag ccagcattcc aacggtttga
    36421 gaaccctgtc cagggaacac aaatgcaaat tgcgtcatgt tttaatcctt atcctagaaa
    36481 cgaaccagcg cggagcccca ggtgaatcca ccgccaaagg cttcaagcag aaccaactgc
    36541 cccggcttaa tgcgcccgtc gcgtacagct tcatccagcg cgcacgggac agaggccgca
    36601 gaggtattac cgtggcgatc cagcgtcacc acgacattgt ccatagacat accgagtttt
    36661 ttcgccgttg cactgataat acgcaggtta gcctgatgcg gaaccagcca gtccagttga
    36721 gaacggtcaa gattatttgc cgccagcgtc tcatcaacga tgtgcgccag ttccgttacc
    36781 gcaaccttga agacttcgtt gcccgccatc gtcagatgaa ttgaattctc tggattcaca
    36841 cggtcagcat taggcagcgt cagcaactca ccatagctac cgtcggcatg cagatgggtg
    36901 gagatgattc ccggctcttc agaggcagcc agcaccgcag cgcccgcgcc atcgccaaaa
    36961 ataataatag tcccacgatc ggttggatcg caggtgcgcg ccagtacatc ggaaccgacg
    37021 accagagcat acttcaccgc cccagatttc acgtattgat cggctacgct taatgcatag
    37081 gtgaaacctg cgcaggctgc tgcaacgtca aatgccgggc aacctttaat gcccagcatg
    37141 ctttgaatct gacaagctgc gctcgggaaa gcgtgcgtag cagaagtcgt tgccacaacg
    37201 atcaggccaa tctggtcttt ctcaatgccc gccatctcaa ttgcgcgtgt cgccgcttca
    37261 aagcccatgg ttgaaacggt ttcgtttggc gcggcaatgt ggcgttcgcg gataccggta
    37321 cgagtgacaa tccactcgtc agaggtgtcc accatttttt ccaaatcggc gtttgtccgc
    37381 acttgttcgg gcagatagct gccagtacca ataatcttcg tatacatgta cgctcagtca
    37441 cttttcggtt atataccgtc acttgcaaac tgcgagttcg ctggcagcgt cctgctaccg
    37501 cagagttccg cttttgccac cgtccagcag ctcaaaacca gctgggtata cagattccag
    37561 gcgagcggca attcgctgag gaacttgtcg ctgcaccgcc tgcactgcct gttcaatcgc
    37621 gaccgcaaaa gctcgctgat tggctgcacc atgacttttt atcaccgtgc cgcgcaatcc
    37681 taacagacag gcgccgttat actggtcggg gttgaggtga ctgaatcgcc tcgtcaggct
    37741 cttttgtagc caacgcttta ataacagtag ccaccacgac cgttttttcc cttcaccctg
    37801 agatttcagc agagaaagga acatcctgac aacaccttcc atcgtcttta acgtgacatt
    37861 tcctgtaaag ccgtcacaaa ccagcacatc tgtcttgcca gttaacaact cattggcttc
    37921 aagatagccg atataattga tagaagggat tgttttaagc accgctgagg catcccgaat
    37981 actgtcgaga ccctttactt cttcttcacc aatattgagc aacgccacgc gaggattggg
    38041 aatttccacc acctcttcag ccaggactga gcccataatg gcaaattgca ccaacattgt
    38101 gctgtcacaa tcgacgttgg cccctaaatc gagaaccacc gttttgccct tttgctgatg
    38161 cggcaatacc gtcaccagcg ccggacgctc aatcccctcc aggggcttga gtaataattt
    38221 tgccagcccc atcagtgccc cggtattacc ggcactgaca caggcttgcg ctcgaccttc
    38281 tttcaccaac tccagggcca cgcgcattga actcccacga ctggcgcgga tagcttgcga
    38341 aggccggaca tcactggcga taactgactg cgcaggaata atctgcagac gcgaacgttg
    38401 ttcaaagtca gctttagcaa gtaatggcgt gatggcgtcg ggattgccga ctaaaagaag
    38461 agtgagttgc gaattagaat tcagtgcctg caatgctgca ggcactgtca cggaagggcc
    38521 aaaatcccct cccatgacat ctaacgccag ggttagacgt gtcaaggtat cgtcgccgcc
    38581 cggtttggtc tttccccagt tgcctgggga aaatcctcac taagcttcat cacgcagacg
    38641 cgtgattact tagcgatgac cttgcggccg cggtagtaac cgtcggcagt gatgtggtga
    38701 cgcaggtgtt tttcaccaga agttttgtct acagacaggc tggtgactgc ggtcagcgcg
    38761 tcatgggaac gacgcatgcc acgtttggaa cgggttggtt tattctgttg tacggccatg
    38821 gaccttactc ctcaattacg gtttatcccc gatccaacgg ggagcaccaa ttacttacgc
    38881 tttaagctgg ctaatacggc aaatgggttt ggcttttgcg cttcttcagg cagttcacca
    38941 aagaccatgt ccgcttcgga cacttcacag tgttcagaat catgcaccgg aactaccggc
    39001 aaggcgagga tgatttcatc ttcaaccatt gcaagcagat cgatttcacc gaattcgtta
    39061 acctcaatcg gttcatacgc ttccggcagt gcttcagcct gttcgtctga acgcacagga
    39121 ctaaaacaat acgttgtgta gacctgatga gtaaacggct tcccgcaacg ctgacactcg
    39181 agcgttaccg tcaccttcgc atcgccgttt aacactgcga gacgttggtt atcgatagcg
    39241 aacgacatgg agcattccac atcactgtcc acactgacta cggattcggc gacgcgctca
    39301 acctgatcag gggtatagat accctggtaa tcaaggcgtt tttgagccgt acgaaccgga
    39361 tcgagagtca ggggtaattt taccttttgc atagggcgcg catattaact ttgtaacgtc
    39421 atagagtcaa agaaaaaggc agcctgtggt tgccttttgc caataattcg cacacattgc
    39481 gggttactgc tttattttcg ttcagtgctg ataacgaaca tcaacctgca aaacgaagcg
    39541 catagtttaa aatggctatc atcaatacgc tatatctgat ggaaaaaaat atgcctaaac
    39601 ttattttagc ctccacctcg ccatggcgtc gcgctcttct ggaaaaactg caaatctctt
    39661 ttgaatgtgc agcaccagag gtcgacgaaa ccccacgcag cgacgaatca ccgcgacagt
    39721 tggtgcttcg actggcacaa gaaaaagcgc aatctctggc gtcacgttat ccggatcatt
    39781 taattattgg ttcagaccag gtatgtgttc ttgatggcga aatcaccggt aaaccgttaa
    39841 cggaagaaaa tgcccgtctg caattacgca aagccagcgg caatatcgtc accttctata
    39901 ctggactggc gttgtttaat tcggcgaatg ggcatctaca aacagaagtg gagccttttg
    39961 acgtccattt ccgtcacctg agcgaggcgg agattgataa ttacgtgcgt aaggagcatc
    40021 ccctgcactg cgcgggtagc tttaagagtg aaggatttgg cattacgctg tttgagcgtt
    40081 tagagggacg tgaccctaac acgctggttg gtttaccgct aatcgcgctg tgtcagatgt
    40141 tacgtcggga agggaaaaac ccgctgatgg gatagttgtt tgcgccggat gcggttacgt
    40201 cgcatccggc aatcggtgca ggcggcctga tgcggcgtaa acgccttatc aggccaaccg
    40261 cccattatca ggcttatatg cttgtattag cgcgcgttac gcagcttttg caaacaacgc
    40321 ttcaaacctt catccatcgg cgcttcgata cgcatcacct caccggtccc cggatgggta
    40381 aacttcaacg ctgcggcgtg caggaacaga cgatttaatc ccgtgcctgc ttcagtgagc
    40441 tgtctgtcaa attcacggtc accgtagcga tcgtcaaagg caatcggatg acccgcatac
    40501 tgtgtatgca cacggatctg atgagtacgt ccggttaccg ggctacaacg caccagggtg
    40561 gcaaatgcat agcgttcttc cactttaaag cgtgtttccg acggtttgcc ttcctgactg
    40621 acacgcacga tacgttcgcc gctttgcaga atatttttca ataacggcgc ttgaacgctc
    40681 ttcacatgcg actgccactg accgcgcacc agcgccaggt aatctttttg cattcctttt
    40741 tcacgtaatt gctcatgcag agaacgcaac gccgagcgtt ttttcgctac cagcaacaca
    40801 cctgaagtgt cccggtcgag acgatgaacc agttcaagga accgcgcttc cgggcgcaac
    40861 gcccgcaaac cttcgataac gccgaagctt aaaccactgc cgccatgtac cgccgtaccg
    40921 gaaggtttat tcagcaccag gatatgatca tcttcatata agatgacgtc cgccagcgcc
    40981 gccacctttt gcagatgtgg cgaaaccgcc tcttcttccc gctcagcaac gcgaaccggt
    41041 gggatacgca cctcatcacc cgcttcgagt ttatattcag gcttaatacg ttttttgttc
    41101 acccgcactt cacctttacg caaaatacgg taaatcatac tttttggtac gcctttcaat
    41161 tgggtacgca aaaagttatc gatacgttgc cccgcttcgt cagcggtgat agcaacaatt
    41221 tttacggatg gagtctctgt tttcatggtg ggcgattcta attagccaac aggattcgcg
    41281 ccactcattt ttctatgctt atatttagtt ttacacctta ttacttcact acgtgatcac
    41341 tttattgatg gttattaaac caatcaccag caagaagtga aaaaactgtg agtaagcggg
    41401 tgataaatgg taaaagtcat cttgctataa caaggcttgc agtggaataa tgaggccgtt
    41461 tccgtgtcca tccttgttaa aacaagaaat tttacggaat aacccatttt gcccgaccga
    41521 tcatccacgc agcaatggcg taagacgtat tgatctttca ggcagttagc gggctgcggg
    41581 ttgcagtcct taccggtaga tggaaatatt tctggagagt aatacccagt ctgtttcttt
    41641 gataattgcg ctgtttttcc gcatgaaaaa cgggcaaccg acactctgcg cctctttgag
    41701 ctgacgataa ccgtgaggtt ggcgacgcga ctagacacga ggccatcggt tcacacccgg
    41761 aaaggcgtta ctttgcccgc agcttagtcg tcaatgtaag aataatgagt aagttacgat
    41821 gaaaagaatg ttaatcaacg caactcagca ggaagagttg cgcgttgccc ttgtagatgg
    41881 gcagcgtctg tatgacctgg atatcgaaag tccagggcac gagcagaaaa aggcaaacat
    41941 ctacaaaggt aaaatcaccc gcattgaacc gagtctggaa gctgcttttg ttgattacgg
    42001 cgctgaacgt cacggtttcc tcccactaaa agaaattgcc cgcgaatatt tccctgctaa
    42061 ctacagtgct catggtcgtc ccaacattaa agatgtgttg cgtgaaggtc aggaagtcat
    42121 tgttcagatc gataaagaag agcgcggcaa caaaggcgcg gcattaacca cctttatcag
    42181 tctggcgggt agctatctgg ttctgatgcc gaacaacccg cgcgcgggtg gcatttctcg
    42241 ccgtatcgaa ggcgacgacc gtaccgaatt aaaagaagca ctggcgagcc ttgaactgcc
    42301 ggaaggcatg gggcttatcg tgcgcaccgc tggcgtcggc aaatctgctg aggcgctgca
    42361 atgggattta agcttccgtc tgaaacactg ggaagccatc aaaaaagccg ctgaaagccg
    42421 cccggctccg ttcctgattc atcaggagag caacgtaatc gttcgcgcat tccgcgatta
    42481 cttacgtcag gacatcggcg aaatccttat cgataacccg aaagtgctcg aactggcacg
    42541 tcagcatatc gctgcattag gtcgcccgga tttcagcagc aaaatcaaac tgtacaccgg
    42601 cgagatcccg ctgttcagcc actaccagat cgagtcgcag atcgaatccg ccttccagcg
    42661 tgaagtccgt ctgccgtccg gtggttccat tgttatcgac agcaccgaag cgttaaccgc
    42721 catcgacatc aactccgcac gcgcgacccg cggcggcgat atcgaagaaa ctgcgtttaa
    42781 caccaacctc gaagctgccg atgagattgc tcgtcagctg cgcctgcgtg acctcggcgg
    42841 cctgattgtt atcgacttca tcgacatgac gcctgtacgc caccagcgtg cggtagaaaa
    42901 ccgtctgcgt gaagcggtgc gtcaggaccg tgcgcgtatt caaatcagcc atatttctcg
    42961 ctttggcctg ctggaaatgt cccgtcagcg cctgagccca tcactgggtg aatccagtca
    43021 tcacgtttgt ccgcgttgtt ctggtactgg caccgtgcgt gacaacgaat cgctgtcgct
    43081 ctctattctg cgtctgatcg aagaagaagc gctgaaagag aacacccagg aagttcacgc
    43141 cattgttcct gtgccaatcg cttcttacct gctgaatgaa aaacgttctg cggtaaatgc
    43201 cattgaaact cgtcaggacg gtgtgcgctg tgtaattgtg ccaaacgatc agatggaaac
    43261 cccgcactac cacgtgctgc gcgtgcgtaa aggggaagaa accccaacct taagctacat
    43321 gctgccgaag ctgcatgaag aagcgatggc gctgccgtct gaagaagagt tcgctgaacg
    43381 taagcgtccg gaacaacctg cgctggcaac ctttgccatg ccggatgtgc cgccagcgcc
    43441 aacgccagct gaacctgccg cgcctgttgt agccccagca ccgaaagctg caccggcaac
    43501 accagcaact cctgcacaac ctgggctgtt gagccgcttc ttcggcgcac tgaaagcgct
    43561 gttcagcggt agtgaagaaa ccaaaccgac cgagcaacca gcaccgaaag cagaagcgaa
    43621 accggaacgt caacaggatc gtcgcaagcc tcgtcagaac aaccgccgtg accgtaatga
    43681 gcgccgcgac acccgtagtg aacgtactga aggcagcgat aatcgcgaag aaaaccgtcg
    43741 taatcgtcgc caggcacagc agcagactgc cgagacgcgt gagagccgtc agcaagctga
    43801 ggtaacggaa aaagcacgta ccaccgacga gcagcaagcg ccgcgtcgtg aacgtagccg
    43861 ccgccgtaac gatgataaac gtcaggcgca acaagaagcg aaggcgctga atgttgaaga
    43921 gcaatctgtt caggaaaccg aacaggaaga acgtgtacgt ccggttcagc cgcgtcgtaa
    43981 acagcgtcag ctcaatcaga aagtgcgtta cgagcaaagc gtagccgaag aagcggtagt
    44041 cgcaccggtg gttgaagaaa ctgccgctgc cgaaccaatt gttcaggaag ctccagctcc
    44101 acgcacagaa ctggtgaaag tcccgctgcc agtcgtagcg caaactgcac cagaacagca
    44161 agaagagaac aatgctgata accgtgacaa cggtggcatg ccgcgtcgtt ctcgccgctc
    44221 gcctcgtcac ctgcgcgtaa gtggtcagcg tcgtcgtcgc tatcgtgacg agcgttatcc
    44281 aacccagtcg ccaatgccgt tgaccgtagc gtgcgcgtct ccggaactgg cctctggcaa
    44341 agtctggatc cgctatccaa ttgtacgtcc gcaagatgta caggttgaag agcagcgcga
    44401 acaggaagaa gtacatgtgc agccgatggt gactgaggtc cctgtcgccg ccgctatcga
    44461 accggttgtt agcgcgccag ttgttgaaga agtggccggt gtcgtagaag cccccgttca
    44521 ggttgccgaa ccgcaaccgg aagtggttga aacgacgcat cctgaagtga tcgctgccgc
    44581 ggtaactgaa cagccgcagg tgattaccga gtctgatgtt gtcgtagccc aggaagttgc
    44641 agaacaagca gaaccggtgg ttgaaccgca ggaagagacg gcagatattg aagaagttgt
    44701 cgaaactgct gaggttgtag ttgctgaacc tgaagttgtt gctcaacctg ccgcgccagt
    44761 agtcgctgaa gtcgcagcag aagttgaaac ggtagctgcg gtcgaacctg aggtcaccgt
    44821 tgagcataac cacgctaccg cgccaatgac gcgcgctcca gcaccggaat atgttccgga
    44881 ggcaccgcgt cacagtgact ggcagcgccc tacttttgcc ttcgaaggta aaggtgccgc
    44941 aggtggtcat acggcaacac atcatgcctc tgccgctcct gcgcgtccgc aacctgttga
    45001 gtaataatta gctcaaagta atcaagccct ggtaactgcc agggcttttt tatttcatct
    45061 ttgaatcaac atattaaaat tcatcgaatg gcatccttgc taaccaacaa tgcaaaatag
    45121 gcaaaaaaat gcccgcccca gcgatcccag agcaggcaga caaaacatac ccagtttcat
    45181 gatatgtttt aaagcgaaat tatttgttga gctggaagag cgacaatccc tgcatatcgg
    45241 taaatgcttt atacgatgcc tgcaatgccg tttgctgcat gatgtaagat gaaatagttg
    45301 cattccagtc cacatcaacc agatcgctca tctgctgcgt ttgccctaaa gcgcgatcgc
    45361 tacctaatga atccagcgac tccagttcgt tcagctgcgt gcctaattcc gcgcgaacag
    45421 tcagcacatt gttcagcgag tttttcagtc cgcggttggt tttatctaac gccgcagcgg
    45481 cggtttcttt atccgcttcg ctatccgcga ccggcgtttt cagggctgcg atggcactat
    45541 ccagcatggc aaaaagattg gtttcagaag cgctaccgtc tggttccgct accgcgttgc
    45601 tggtaatact gtcgaaaatt ttgtcacccg tgtgccctat caccatcgaa cgcgaagcat
    45661 cgacctgttg tttaatactt tctgctccac cgacgtattt ccctttctct tcgctaaacg
    45721 gcgcagtctc tgttttataa ccggcaaaaa tgtagcgccc gttaccgtca gtggtgttcg
    45781 ccagattcag caactggtca cgaagcccct gaatatccgt agccagcgag gcccggtcat
    45841 cgtcactcaa ggtgccattg ctggcgtaga caattttttc ctgagcattc tggatagcag
    45901 tggtgacctg gctaagtaca ctctcttcca gtgacacttt ttgagtggcg aaagtacgtg
    45961 ccagcgtgta ctggctgttt tgcgcctgtg cctgggagag aacaacagct tgtgatgcag
    46021 caatgggatc gtctgaaggg ttaacgactc gcttacccgt cgacatctgc tcgccgtact
    46081 tcatccattc tgcctgagaa ttggtgatgc cgcgcatgtt ttgctggtac atcatctggg
    46141 tactgaaacg cattttatct ccccttagcg aatgttaatc agcgcatcaa aaatcgcgtt
    46201 tgccgtctgc agaacctgcg cattcgccag gtaatactgc tgaaaacgtt gcagatttcc
    46261 gtactcctca tcgagattga caccggaaat cgactgctgc tgattggaaa gctgcgtcac
    46321 cacattacct tgcgtggtgc tactggtttt caacgtcgcg gttttattac cgatatcact
    46381 cactaacgag gcataagcgt cgttaaagga tttcgcaccg cccaccgttt tactgttgct
    46441 ttgcagatcc agcagggcct gaccgttgcg gttgtcgcta tcacccgcat cttcttcgct
    46501 cgccatcgcg attttcgctt cgtcggtgat taatacatcc atgttgacga tggcgtcact
    46561 tactggtttc agcgtgaagc tgtcgttaac ggcaggcgtt cctgtaaacg tcaactccag
    46621 accatcaaat gccactttac cgttggcatc tggtgtcgcc gtaaaagtgg tattgctggc
    46681 aaggcgggtg acctgccact gattattatc gaacgagatt ttgtaatctg tcgccagtac
    46741 cacggaggca tcagttaccg tggcaccgat cgcaacgtca cctttgtttt tcgtgttttg
    46801 cagaaccgcg ggcttaccga tagtaaagaa atcttcacca gcatcgccgt tagcatcaaa
    46861 tccggctttg tgttggctgt tgaaagcctc ggcaaatgcc agcgccagtt gtccaagcgt
    46921 attacgcgtc tggtccagat cctgagaacg gaatgtcaga atgccgccca gcgacccggt
    46981 attcagtaat ttctccggga tctcaatatt gcctgccgtc ccatcaacgt aagcgacagt
    47041 cgtacgagaa gggtcggcgc tggaaggaac tgccgccagt tgccgcgccg tacttccctg
    47101 aaccagtgag taaccattgg ccatcgtgat gttataagta ccgccatcct gaacgctgac
    47161 ttctacgcca acaatctggt ttaattcgct caccagttga tcgcgttgat ccagcagatt
    47221 gttaggtgac gcccctgccc ccacgcctgt caggcgcgag atttgatcgt tcaggctggc
    47281 aatttgttta gcgtaattgt tgatctgatc aacgctggca cctatcgcga tattgacctg
    47341 tttgtcctgg tcgcgcagat attgatcggt ggttttaaac tgattcacca acccttctga
    47401 tttcccaatc agcgcctggc gcgctgccgg gtcttccgcg ttactcacca gcgtttgcag
    47461 gctggtgaag aaatcctgca tctgtgttgc cagcgaagag gtactggtgg agagcatatt
    47521 gtcgattttc gacatctgct catagcgggc agtcaggccg ctactttgcg tctgcgcagc
    47581 acgtaactgg ttggtaataa acgcatcata ctcacgctgc acaccagaaa cgtagacgcc
    47641 attgccaacc cagccgccag cgcccaacgt gctattggcc tgcgccataa tagtggtttg
    47701 gcgggtatat ccggcaacgt tatagctgga gatattatta cttgccgtat ttaacgccgc
    47761 ctgggccgcg ttcagtccgc tcatggcgtt attaatcaag ctggacatgg aggttcctta
    47821 taagccttca attacagagt attatcggca gcgacccgcc ggacttgagt tattcagaac
    47881 agattatcaa tgttcatact gtaggttttg ctcaccttgt cgcttatcga tttcatctgc
    47941 tgaatcatgt tggtgagttt gcgggcatag tgaggatcgg tggcatagcc cgcgtcctgt
    48001 agggcctgcg ccccctgttc cgcactcgcg gcggtcgtca cggcggcgta gcgcgggtta
    48061 cgcgttaaca gcccaacgta atccgacaag gcttccagat acgagctgta gacgcgaaac
    48121 ttcgctttta ctttcttcgc ttcgccgttt tcatattcag tcgtggtgat ttcagtaact
    48181 ggccctttcc agttgccaga ggctttgaca ccaaacaggt tatagctcgg ctcgccgttt
    48241 tcgcggcgga tttgccgttg cccccaacca gattccagtg ccgcctgagc gaggatcaaa
    48301 tgatgtggca caccgctttg ctggcttgcc agttgggcgg gcagcgagag ttgcgcgagg
    48361 aatgctttac tgtcacccgg cagcgaatca tcgtagttac gtggcacggc cttttgcacc
    48421 agctgcgaaa gcgcctgatt ttgataacgc accacagttt cgagcgggaa tttcatcggt
    48481 gctgctggcg tggactcctc tggcaatggt tgttctggcg tcatctgttt aaccatcatc
    48541 tctgcaagcc ccagaccttt gcccgccgtc atctgttggg caatttgctg gtcatacata
    48601 ctggtataca gacgagtgtg ctcgctgctg aacaggccat cttttggtaa agcgtcgcgc
    48661 atgcttttca acatcatctg cacgaacatc ccttccacct gacgggccac cggacggata
    48721 tttgccgccg gatcttcgcc cactttcgcc tttagttcgt tgagtgattg cgcatcccag
    48781 gccgcacttg ccagtagttt gctgtcgctg atcatcagat gatttccagt tttgcccgca
    48841 gacatcccgc actttgcatt gattgcaaaa tagacatcag atccatcggc gtagcgccca
    48901 gcgcattgag cgcgcgcacc acgttattga ggctggcgct ggaacgtacg ctttgcagcg
    48961 aaccgccgct ctggcgtaaa tcgatctgcg tttgtggagt aaccacagtc tgtccaccac
    49021 caaacggtgt atctggctgg ctgacattgg cctgacgatt gactgttact gagagatttc
    49081 cctgcgctac cgcgcagctg tcgagggtca cttcgcgatt catcaccacc gaaccggtgc
    49141 gcgagttaat cactacttta gcgtcctgcg gggtgacatt aacctgcata ttctggatat
    49201 ctgcaaggaa acggacctgg gaactgttgc cacttggtac gcgcacctga atagtccgcg
    49261 catctaacgc ggtggcgctg ccatatccac gcacgcggtt gatggtgtca gcgatttgct
    49321 gcgccatgct gaaatcttcg tcgttaagtt gcaaattaag ggtattcccg acgccaaact
    49381 ggctgggcaa ttcacgttca ataaccgcac cattggtgat ccgtccaccg ttcagttggt
    49441 tcacctgaac actgctaccg ccagcggagg ctcctgcgcc gccaaccaga atattgccct
    49501 gcgccagcgc atacacctga ctgtcaacgc ccttaagcgg cgtcatcaac aacgtacctc
    49561 cacgcaagct tttggcattt cccatggaag aaaccaccac atcgatggtt tgcccctgac
    49621 gtccaaacgg aggaagtgac gctgtcacca ttaccgcagc gacgtttttt agctgcatat
    49681 tggtgcccgt cggaacggta attcccagct gtgagagcat gttattaagc gtttgtgtgg
    49741 taaacggcgt ctgggttgtc tggtcaccgg tgccatccag ccccaccacc agaccatagc
    49801 caatcagtga gttttgcctt accccctgaa cactggtgag atcgcgaata cgctcagcct
    49861 gagccgccgt cgtgaccagt agaagaatta atgcagagag aaatttaatc accacagcct
    49921 cacttacatt ggcgacaggt taaggaagaa acgctgcaac cagcccatat tttgcgcttc
    49981 gttaatgtag ccattgccta cgtattcaat gcgcgcatcc gccacctgag tagacggtac
    50041 ggtattgctg ccgctgatag tgcgtggatt aaccacgcca gagaagcgaa taaattcggt
    50101 accctgatta atggcaatct gtttttcacc caccacatgc aggttgccgt tgaccagtac
    50161 ctggtcaacc gtcaccgtca acgtgccgct aaaggtattg ctggcattgg ccccgccctt
    50221 tccgttgaac gtgttaccac cggaggcttc gacatcggca cgagcgttac caaacagccc
    50281 ctgcaaatag cgcggcacag tatcaaagcc aaaattagtt ttaccgtcac ggctggcatt
    50341 cgcagaggag cttttgctgg cgctgacgtt ctcctgcaac acgatggtca gcgtatcgcc
    50401 aatattgcgt ggtcgacgat cttcaaacag cggttgatag ccatagttaa tcggctgagc
    50461 agactggaaa atagaaccgt tggcgacggg cgtcggaccg ggaaccggtt gtgcactggt
    50521 cgccccctgc accagcggcg tggagggtat ccaggcgcag ccggttagtg aaagcaccaa
    50581 caagctggaa atggcataag tatgcgcagc gtttttttgc atggctatca tcttcaaaaa
    50641 tcagtaaacc ggtgaacctg ccaccggtta agccttagag ttgcgtcagt ttttgcagca
    50701 tctgatcggt ggtggacacc gctttactgt tgatttcgta agcgcgttgc acctgaatca
    50761 tattgaccag ttcttccgcc acgttgacgt tagacgtttc aacataccct tgatacagca
    50821 gtcccgcgcc gttcaggccc ggcgtgcttt cgttcggtgc accagaggat tgcgtttcgg
    50881 tgtagaggtt ttcgccaatg ctctccagcc cggtgtcatt cataaaggtg gtgagattga
    50941 gctgcccaac ctgaaccgga gctgcctggc cttgttgggt tacgctgacc acgccatcac
    51001 gaccgatggt gatacttaac gcattcgccg gaatggtgat cgctggctgc acctgaaaac
    51061 caccagccgt caccagctgc ccgttctgat ccacctggaa agagccgtca cgggtatagg
    51121 ctgatgaacc atctggcaac atcacctgga aaaagccctg ccctttaatc gcgacatctt
    51181 tgctgttgtt ggtctgcgac aggtttccct ggctgtgtaa gcgttcagtg gcgaccgggc
    51241 gtacccccgt gccgatttgt aatccggagg gtaaggtggt ttgttcggaa gactgtgccc
    51301 ccggctggcg aatggtttga taaagcagat cttcaaacac cgcgcgctga cgcttaaaac
    51361 cgttagtact gacgtttgcc aggttgttgg caatgacgtc catattggtt tgctgggcgt
    51421 caaggcccgt tttggcgatc cataatgaac tgatcataaa atgtcctgta gtggattagt
    51481 gacaagcaga gcagaagcac gcgacagtgt gaatttcccc tcaccctaac cctctcccca
    51541 aaggggcgag ggaatagtcc gcgcgctttt attgcaatgt catcaatcgt tcaattaact
    51601 catcgacagc agttggttgg cacggcctgc gttatcatcg acgctgctga tcaccttcat
    51661 ctgcatttca aaacgccgcg cgctggcaat catgtcgctc attgccgcaa cggcattgac
    51721 gttactgcct tccagaaccc ccgacatcac acgcaaggtt ggatctgcct gcagtatcgg
    51781 cccacgcgtg gcctggcttt ctgcgcttaa acgaaaaatg ccgtcgtcac cgcgttgcac
    51841 ttcgctgccc gtggctttca ccagtttcag acgccccact ggcgcaaccg tatttgccgg
    51901 atcgcccgga ttgagcgccg agattgtgcc atcggcagca atagtgattt ccgccccttc
    51961 cggcacagca attggcccag cctcgcctat caccggatgc ccctgaattg tcagttgccc
    52021 ggtgggatca acctgaatgc tgccattacg cgtataccct tcgctgccgt cagcggactg
    52081 cacggccagc cagccatcct gctgcaatgc aacgtccagc gggcgcgagg tgtaatccat
    52141 cttgccgggc gtcatgtctg cacccggtgt tgacgccgtt accagcgtgc gcgtgggcag
    52201 tgaaagccct tccaccggca ctgcacgcaa ggcgtttaac tgcgcgcgaa aaccgggcgt
    52261 agaggcattg gccagattac tggcggttac cgcctgttga ttcagcgtct ggctggctgc
    52321 tcccatcgcg gtataaattg cgtgatccat tgagctatcc cgtcagcgat tagcgtaagt
    52381 taaccagcgt gttgaggatc tggtcctggg ttttgatggt ctgggcgtta gactgatagt
    52441 tacgctgggc aacgatcata ttgaccagtt ctttactgag atcgacgttg gacgcttcca
    52501 acgcaccgtt ggtcagggtg ccaaagttgc ccgtcccggc tgtccccaac agcgccacgc
    52561 cagaagattg cgtcgcagac cagacgttgt cgccttcgga tgccagacct tcgttgttgg
    52621 caaagttcgc cagtacaatc tgccccagca gttgtgtttg ttcgttggaa tagttgccga
    52681 caaccgtacc gtcatcattg atttgataac tcaccagatc gcccggtttg tagccattct
    52741 gggtggttgc cacaatattg ttagcgccgg tattttgctg catggagttg aggaagctca
    52801 ggctaaacgt ggcgggatct gcgccgttaa ttgcgccagt ggtaatattc tctgttggat
    52861 ttgaggtcag aacgccattg gcattaaaca ccagcttcat tgcaggctcg gctgtacctg
    52921 ttggatcact gctatcctgg gtgtagacct gccagttatt atccccggtc ttcacaaagt
    52981 agacgctcat gtcatgagca ttaccctgac tgtcgaaaac agtcaccgaa ccttttttgt
    53041 tatagctatc cgcattgctg gcgctgaatg gcgtaacagt aggaagcgga tcactggaat
    53101 tcaggttgat ctgcatcgat gccgtggtgg tagttttcgc tgccatcagg gtattcggga
    53161 tcgaaatatt ggtcggattc gccccttgct gaatagtcgg cggcgtaccg gttgccgggt
    53221 aacccgtcag ctgtaaacct tgcatattca ccaggttacg gttttcatcc agcttaaatt
    53281 gtccgttacg gctgtagaac accgaaccgt tgctgtctac cagacggaaa aaaccgttct
    53341 ggctgatagc aacgtccaga cctcgcccgg tgttggtggt cgtgccatcg gtaaagtcct
    53401 gagtgatacc ggcaactttt acccccagtc ccactttcga accggcaaac atatcggcaa
    53461 aagaggccgt gcctgattta aagccgtagg tggcggagtt ggcgatattg ttgccaataa
    53521 catcgaggtt ggtggcggca gcgtttaatc cgctaaccgc ttgagaaaag gccatgactg
    53581 actcctgaaa tgtgaaggct taaattatct gccgtacttc gtcgagggtg gtggtgccgt
    53641 aagtgccgag atccagcgta ttaccgctgt tgccgcggat cacaccctgc accagagcaa
    53701 actgcagcgg ctgggcaacc agttgtgtac caccgttact ggcgctaatc gctacattgt
    53761 aagaaccgtt cggcgcagtg ctgccgtcag tcaacgtacc gtcccaggtg aaactgtgaa
    53821 ctccggcggt cagttcacca atatcaatgg tgcgcacaac cgcaccattt ttatcggtga
    53881 tggtggccgt aactttgtct gccgcctgtt gcagctcaac accaaacggc gtggtcgtgg
    53941 tcacagctcc ttcttcactg ccggttcccg caagaacagt ggtgccgtgg atcatcacgc
    54001 cgtgaccgat caggttactg gcctgtaacg actggctgtt atcaatctgt ccggaaatag
    54061 atccgagtgt ggtattgagt ttttcaatcc cgctgaccgt gctgatttgt gccaattgcg
    54121 acgtcagctc gttgttttcc attggattgg tcgggtcctg gtttttcagc tgcgccacca
    54181 gcaaagtcag aaaactgctt tgtaaatctg cggcgttgct gcccgtgagc gaactactgc
    54241 tggtggtact gacgccggta tttgtcggat cggtggtggt taccgcaatg gacatagctt
    54301 tctcctttat tgaccgagcg taagggtttt cagcatcatg cttttcaccg tgttgagcac
    54361 ttcaacgttg gcctgatagc tgcgtgacgc cgacatggtg ttaaccatct ccccgacgac
    54421 atcaacgttc ggcattttta cgtagccctt tgcatctgcc agcggattac ccggttcata
    54481 aaccagtttg tccggggcct gactttctat aacatcggca acctttacgc cgcctgtcgc
    54541 agcacctggt gcagcgttaa cctggaatac cacctgtttt gcccgatatg gctgtccatc
    54601 aggaccggtc acgctatcag catttgccag attactggcc gccacgttca ggcgctggga
    54661 ctgggcagtt aacgccgacc cggcgatatc aaaaatattc agcagtgcca tccgttaatt
    54721 tccgctctgt aaaacgttca tcatgccttt gatttgcccg ctcaacgcgc taaggctcat
    54781 ctggtattgc aggctgttat cggcaaactg ggtgcgttcg cgatccatat cgacggtatt
    54841 accgtcaagc gaaggctggt ccggaatacg gtattgcagt tctgcggtag gaggcgtcag
    54901 cgcctgcgcc gggatgtgtt gcgttgaggt catcgtcagt gcaaccacac tggttgcatc
    54961 ccgtccacgt tgcatgactt ttttaagttc actggcaaaa tcgatatcgc gcgcctgata
    55021 accaggggta tcggcattgg cgatgtttgc tgccagcact tcctgacgct gggcgcgcag
    55081 attgagcgcc tcttgttgaa aacgtaaggc ggcgtcgagc ttatcgagca tatctcctcc
    55141 gcaggtatca aaattctgcc atcagcttaa atgcctttac gcgcgcgtta tcggcggaat
    55201 aaacgcaaaa tgggtcgcta tttatgccgt tgatggtcat tgcggacagg tacaattcac
    55261 gttgtagaaa tggctggggg cgaaaatgct gacaataaaa cgtagcgtgg cgatcatcgc
    55321 gatactgttc agtccgttaa gtacggcgag caatctcaca tcgcaattgc acaacttttt
    55381 tagcgcccaa ctcgcggggg taagtgatga ggttcgtgtt tctattcgta cagcgcccaa
    55441 tctactaccg ccatgcgagc agccattgct ttcgatgagc aataattccc gcctgtgggg
    55501 caatgtgaat gtgttggcac gctgcggtaa cgacaaacga tatttacagg ttaatgtgca
    55561 ggccacagga aattatgtgg ttgccgcgat gcccattgtg cggggaggaa agctggaagc
    55621 tggcaatgtc aaactaaaac gcggacggct ggataccctg ccaccgcgta cggtgctgga
    55681 tatcaatcaa cttgttgatg ccattagcct gcgcgatcta tcacccgatc aacctatcca
    55741 gttaacccag tttcgccagg catggcgggt aaaagcggga caacgcgtca atgtgatcgc
    55801 cagcggtgat gggtttagcg ccaacgcaga aggtcaggcg ctgaacaatg cagccgtcgc
    55861 acagaatgcg cgggtgcgca tggtatcggg acaggtagtc agcggcgttg ttgatgcaga
    55921 tgggaatatt cttataaacc tgtaagctgt taaagattac ccgtcccttg ccgataaata
    55981 agcaacacat gataaaagcg ccctcaatga ggaataaacc atgagtattg atcgcacttc
    56041 gcctctgaag cctgtaagca ccgttcaacc gcgcgaaacc actgacgcgc cggtaacgaa
    56101 cagccgggcg gcaaaaacaa ccgcctccac cagcaccagt gtgacgttaa gcgacgcgca
    56161 agcaaaactg atgcaacccg gcagcagtga tatcaatctt gaacgtgtcg aagcgttaaa
    56221 actggcgatt cgtaacggtg aactaaaaat ggacaccggc aaaattgccg atgcgctgat
    56281 caacgaagcg cagcaagact tgcagagtaa ctgatcgtat gacacgtctt gcagagatcc
    56341 tcgaccagat gtccgctgtg cttaacgatc tcaaaacggt aatggatcaa gagcagcaac
    56401 atctctctat ggggcagatc aacggcagcc agttgcaatg gattacagaa caaaaaagct
    56461 cactgctggc gacgctggat tacctcgaac agttacgcaa gaaagaaccc aatacagcaa
    56521 atagcgttga tattagtcaa cgctggcagg aaattactgt gaaaacgcag caactacgcc
    56581 aaatgaatca acataacggc tggttactgg aaggacagat tgagcgcaat caacaggcgc
    56641 tggaaatgtt gaaaccgcat caggaaccga cgctatatgg ggcgaacggt cagacctcaa
    56701 caatccatcg cggcggtaaa aagatttcga tctgaatatt atctccggcc tgcactgcag
    56761 gccggaatgc attgttacac cgtccggcgg gcaaattctt taactttgaa gcccagtacc
    56821 gccagtgcag cgaagtacgc ggcaatcccc gccagcacga ccgccattaa acgcagtaag
    56881 cgccagggca tggtacccaa tgaccactcc ggcatgatat gtaacatacc taaaagcacg
    56941 ccagacatca ccagtaccgc caccaccaga cgcaacagaa acgccatcca gccgggttgc
    57001 ggggtaaaga ttttctgctt acgcaactgc cagtaaagca gcgaagcatt cagacacgcc
    57061 gccagaccaa tagaaagtga cagcccggca tgtttcaacg gaccaataaa cgccaggttc
    57121 atcaattgcg ttaaaatcag cgtaacgatg gcaattttca ctggcgtttt aatgtcctgg
    57181 cgggaataaa agccaggagc caaaactttc actacaatca ggccaatcaa acccaccgag
    57241 taggcaatta acgcccgctg ggtcatcagc gcatcaaagg cggtaaattt accgtactgg
    57301 aacagcgaaa cggtcaacgg acctgaaaga atgcccaacg caaccgcact cggcagcgcc
    57361 aacaggaaac aaagacgcag cccccagtcc atcaaacggt tgtattcatc atgattgcca
    57421 ctggcaaaac tcttcgacag cgacggcagc aaaatggtgc caagcgccac gcccagcaca
    57481 ccagacggaa actccattaa gcggtcggcg taatacatcc aagacaccga accggaagca
    57541 agaaacgagg caaaaatggt gttgatgatt aaggagatct ggctcacaga gacgccaagg
    57601 atcgccggtc ccatctgttt caccacgcgc attgctccgg catcgtggaa gttaatgcgc
    57661 ggcaggacca gcatgccgat cttcttcagg tgcggtagct gatacaccag ctgcaggatg
    57721 ccgccgaccg taacagccca cgccagcgcc agcaccggtg ggttaaagta cggtgcggca
    57781 aacagcgcga aaccaatcat gctgatgtta agcagtgctg gagcaaacgc cggaatcgag
    57841 aagcggttcc acgtattcag aatcgctccc accagcgacg ccagggagat cagcaagata
    57901 tagggaaagg taatctttag tagctggctg gtcagggcaa atttgtcggc agtgtcagcg
    57961 aagcctggcg cggtcaccat gatcacccac ggtgcggcga gcatgccagc gaccgtcaca
    58021 accgccagcg cgagtgtcag caggccagaa acataagaga caaagacccg cgtggcgtct
    58081 tcaccctgct tacttttata ttccgccaga atcggtacaa atgcctggga aaatgcccct
    58141 tcggcaaaga tacggcgtaa caagttagga agtttaaaag cgacgaaaaa ggcgtcggtt
    58201 gccatccctg cgccaaagat tctggcgaca attgcgtctc gtgcgaagcc aagcacacgc
    58261 gaaaacatgg tcatcgagct gacggcggcc agcgatttta ataaattcat cggtgttcta
    58321 atccagaccc acgggcaaaa cgcctgcaag gcaggcgctg aaagaggcga atagtctacc
    58381 tggattatgg tgaattgcta ccgccagatg ttacagggtt tattcactca tcgcatcgcg
    58441 ccagatcttg tcaacgatac gttgcgccag cacggcctgt tcgccggcgg tttgcggaac
    58501 tgtctgattt tgcacacatt caatgaagtg ccgcgcacag ccgacaaatc cacgttgttc
    58561 aagagtgctc tgccaaccag gaatcggttt atgcactacg ccctgcccgc gctcctcacg
    58621 ccattcgcgc atatccgtaa tgtcgatgag cgcaccgtca gtcacggcct gcacggtttc
    58681 acgctgactt ccggcacggc gatgcataca ggtggtgatc tgcaaaggac cggccgaaaa
    58741 atggtgctcg gcaaacagca tttcgccagc gtcgttagtc agtagcgtac cgccatccag
    58801 agaggctttg ccgcccgaca accacagcgc ggtatccacc acatgcagat aatcatccag
    58861 caacgtgaaa taaagatcgt gtggcccgac actattgcta cgatgtttat ccattcttag
    58921 cgaagctgcg gtagcgagtt gcgtttttaa ctcaccgtag agtggtgcga aacgacggtt
    58981 aaaaccgacc atcaacgtca gttttttacg cgccgccagt tccaccagcc gttcagcatc
    59041 gcgcagattt tctgccagcg gtttatcgac acagacatgt acacccgcat tgagtaacgt
    59101 actgaccacg tcaaagtggc tggcggtgct ggaatgcaca aaaaccgcat cgcaactggc
    59161 ggcaaggctg gataacgaat cggcataagg aatgcgccag ctttcacaaa ttggcagggc
    59221 tttcgcgcgc gtaggcgacc aggctccttg taacgtccag tcagacgctg ccgccagcac
    59281 cggtaaccac gctttttgcg caatgccacc taatcccact acgccgatac gtaatttttt
    59341 cactttaatc tcccagatgg gccagcaacg aatcaagacg ctgtttcagt tctgccactt
    59401 cgatttccag ggcttcgacg cgggcctgta aatcaccatc aaccgcgttc gacatatccg
    59461 tcaccgccgg ctgatcttca acctcaccac tgaaaagatg catgtagcgg ctttcgcgtt
    59521 tacccagttc gcgggccaga cgcaccacaa aaggaccatc ttcgcgattt gccagttgtt
    59581 ccagcgtcga ctccacttcc gccatatcgc tgaattcata cattcgcgcg gcgcagctgc
    59641 gcagttcacc tggcgtctgg gcaccacgca ataacaacgt ggtgattaac gccacttccg
    59701 ctgcgctcag tttcagatcg ccaaattctg aattacaaaa acgttgctca tatttggtga
    59761 cccgattacc aaaaccgctc actgtgcgta gataatgacg tttgaccaga ttatccagct
    59821 gttcctgcac ttcggattca ctcagattca tgaccggttc acggttcgtt ttctgattac
    59881 aggccgtgac tacaccattg actgagagcg ggtattgctc cggcgtggtc acctgctttt
    59941 ccagcaagca accaatcacg cgagcttcaa gggcagtaag ttgatatttc atgagattct
    60001 ccttagcggc cgggcgtcca gtctggggta gttaatgccg tcagtacgtg atcgcgccat
    60061 tgtccatcaa tcaacagata gtctttcgca tagccttctt tttcaaaacc cagtcgcgcc
    60121 agtaaatcac cgctgcgttt attgtgcggc atataattag ccataatgcg atgaatatgt
    60181 tgggtgcgct gcatataacg aatggctgcg gtcagggctt caaacatgag tcctttgccc
    60241 tgccattttt gcccaatcga ataaccgaga tagcaggcat gaaaagagcc acgaacaaca
    60301 ttggaaaaat tggcaacgcc aataatctct ttttcgtccg ggtcgaataa gccaaagtag
    60361 aaagctgaac cttgtttatg aaattcgtta atcatcccca gcctggcctg ccagcctgat
    60421 ggataacagt ggctttcgtc gcgcactggc tcccagggct tgaggaaatg gcgattctct
    60481 gcgtaataat ccgcaagacg ccaggcatca cgatcatgca ccagacgcac gaccagtcgg
    60541 tctgtggtta agcgcacttt tggcacgtta ctgcgatagc caaacattct atacctactc
    60601 cttcccgtaa cgtctttaat acgctgtaag tattactata cctgcgcaac cagaccctgt
    60661 gaaaagtcca aaatgccatt ttctgcatta ttcacatatt tgataaaaac tctctatcaa
    60721 agcgacgttt tgataaaaaa atattgtccc cgaagtgatg ggaaaagtct tagcggcaat
    60781 gcagaataga aagtgctcat cttttatttc ccgggagggg aaatgtcccg cgtatcgcag
    60841 gcgaggaacc tgggtaaata tttcctgctc atcgataata tgctggtcgt gctggggttc
    60901 tttgttgtct tcccgctgat ctctatccgc ttcgttgatc aaatgggctg ggccgccgtc
    60961 atggtcggta ttgctctcgg tctacgccag tttattcagc aaggtctggg tattttcggc
    61021 ggcgcaattg ccgaccgctt tggtgccaaa ccgatgattg ttaccggtat gctgatgcgc
    61081 gccgccggat tcgccacaat gggtatcgcc cacgaaccgt ggctattgtg gttttcatgc
    61141 ctgctctcgg gactcggcgg cacgttgttt gatccgccgc gttcggcgct ggtggtgaaa
    61201 ctaatccgtc cacaacaacg tggtcgtttt ttctcgctgt tgatgatgca ggacagtgcc
    61261 ggtgcggtca ttggcgcatt gttggggagc tggctgttgc aatacgactt tcgcctggtc
    61321 tgcgccacag gggccgtttt gtttgtgctg tgtgcggcgt tcaatgcgtg gttgttaccg
    61381 gcatggaaac tctccaccgt acacacgccc gttcgcgaag gcatgacccg cgtgatgcgt
    61441 gacaagcgtt ttgtcaccta tgtcctgacg ctggcgggtt actacatgct ggctgtacaa
    61501 gtgatgctga tgctgccaat tatggtcaac gacgtggctg gcgcaccctc tgccgttaaa
    61561 tggatgtatg ccattgaagc gtgtctgtcg ttaacgttgc tctaccctat cgcccgctgg
    61621 agtgaaaagc attttcgtct ggaacaccgg ttgatggctg ggctgttgat aatgtcatta
    61681 agcatgatgc cggtgggcat ggtcagcggc ctgcaacaac ttttcaccct gatttgtctg
    61741 ttttatatcg ggtcgatcat tgccgagcct gcgcgtgaaa ccttaagtgc ttcgctggcg
    61801 gacgcaagag ctcgcggcag ctatatgggg tttagccgtc tgggtctggc gattggcggc
    61861 gctattggtt atatcggtgg tggctggctg tttgacctgg gcaaatcggc gcaccagcca
    61921 gagcttccgt ggatgatgct gggaattatt ggcatcttca ctttccttgc gctgggttgg
    61981 cagtttagtc agaaacgcgc cgcgcgtcgt ttgcttgaac gcgacgcctg atttgatact
    62041 cccccctgac tcctccatac tgaaagtgaa ctgacagcca aatggaggag tcacgtgaag
    62101 ctatacattt acgatcactg cccttactgc ctcaaagccc gcatgatttt cggcctgaaa
    62161 aatatccccg tcgaattaca tgttctgctc aacgacgacg cagaaacacc cacccggatg
    62221 gtcggtcaaa aacaggttcc cattctgcaa aaagatgaca gccgctatat gccagaaagc
    62281 atggacatcg ttcactatgt cgataaactc gacggcaaac cgttactgac cggcaaacgt
    62341 tcccctgcca ttgaagagtg gctgcgcaag gtcaatggct acgcaaacaa actgctgttg
    62401 ccgcgttttg ccaaatcggc atttgatgag ttttctactc ccgccgcgcg caaatatttc
    62461 gtcgacaaga aagaggccag cgcgggtaat ttagccgacc tgctggccca ctctgacggt
    62521 ctgattaaga atatcagcga tgatttgcgt gcgctggaca aactgatcgt caaaccgaac
    62581 gccgtgaatg gcgaactttc ggaagatgat attcagctat ttccgctact gcgtaatctg
    62641 acgctggtag ccggaatcaa ctggccaagc cgcgttgctg attaccgcga taatatggcg
    62701 aaacagacac aaatcaattt gttatcatca atggcgattt aatcctgacc cgccgcggca
    62761 gcctgtattc gcgggttgcc gccgttttca gttttttctg ctggcgagtt tatcgctggt
    62821 gacacatgct gcgttgtgtc aggatattga cgcagatttc atgtcgagga ctaccatgaa
    62881 caagttttta tttgccgctg cattgatcgt cagtggcctg ctcgttggct gtaatcaact
    62941 cacccaatac accatcaccg aacaagaaat taaccagtcg cttgcgaaac ataataattt
    63001 ctcaaaagat atcggtttac ccggcgtggc tgacgcccat attgttctga caaacttgac
    63061 cagccaaatt ggtcgcgaag agccgaataa ggttacccta accggagacg ccaatctgga
    63121 catgaactcc ctgttcggta gtcagaaagc gaccatgaaa ctgaagctga aagcgctgcc
    63181 cgtgtttgat aaagaaaaag gtgcgatctt cctgaaagag atggaagtgg tcgatgcgac
    63241 ggtacaaccg gaaaaaatgc aaacggtgat gcaaacgttg cttccctatt tgaaccaggc
    63301 attacgcaat tactttaacc agcaacctgc ttacgtcctg cgcgaagatg gcagtcaggg
    63361 cgaagcaatg gcgaaaaaac tggcgaaagg cattgaagtg aagccaggcg aaattgtcat
    63421 tccgtttacg gattaatgac gagggcgcat tcgcgccctt tatttttcgt gcaaaggaaa
    63481 acgtttccgc ttatcctttg tgtccggcaa aaacatccct tcagccggag catagagatt
    63541 aatgactgca ccatcccagg tattaaagat ccgccgccca gacgactggc accttcacct
    63601 ccgcgatggc gacatgttaa aaactgtcgt gccgtatacc agcgaaattt atggacgggc
    63661 tattgtaatg cccaatctgg ctccgcccgt gaccactgtt gaggctgccg tggcgtatcg
    63721 ccagcgtatt cttgatgccg tacctgccgg gcacaatttc accccattga tgacctgtta
    63781 tttaacagat tcgctggatc ctaatgagct ggagcgcgga tttaacgaag gcgtgttcac
    63841 cgctgcaaaa ctttatccgg caaacgcaac cactaactcc agccacggcg tgacgtcaat
    63901 tgacgcaatc atgccggtac ttgagcgcat ggaaaaaatc ggtatgccgc tactggtgca
    63961 tggtgaagtg acacatgcag atatcgacat ttttgatcgt gaagcgcgct ttatagaaag
    64021 cgtgatggaa cctctgcgcc agcgcctgac tgcgctgaaa gtcgtttttg agcacatcac
    64081 caccaaagat gctgccgact atgtccgtga cggaaatgaa cggctggctg ccaccatcac
    64141 tccgcagcat ctgatgttta accgcaacca tatgctggtt ggtggcgtgc gtccgcacct
    64201 gtattgttta cccatcctca aacgcaatat tcaccaacag gcattgcgtg aactggtcgc
    64261 cagcggtttt aatcgagtat tcctcggtac ggattctgcg ccacatgcac gtcatcgcaa
    64321 agagagcagt tgcggctgcg cgggctgctt caacgcccca accgcgctgg gcagttacgc
    64381 taccgtcttt gaagagatga atgctctgca gcactttgaa gcattctgtt ctgtaaacgg
    64441 cccgcagttc tatggcttgc cggtcaacga cacattcatc gaactggtac gtgaagagca
    64501 acaggttgct gaaagcatcg cactgactga tgacaccctg gtgccattcc tcgccgggga
    64561 aacggtacgc tggtccgtta aacaataaaa atcgtagctt cctgttgtca ttaggttatt
    64621 ttacctgtat aaataaccag tatattcaac agggggctat tatgcgaatt gaagtcacca
    64681 tagcgaaaac ttctccattg ccagctgggg ctattgacgc cctggctggc gaactttccc
    64741 gccgtattca gtatgcgttt cctgataatg aaggccacgt atcggtacgt tatgccgcag
    64801 cgaataattt atcggttatt ggcgcaacaa aagaagataa acagcgcatt agcgaaattc
    64861 tccaggaaac gtgggaaagc gccgatgact ggtttgtcag cgaataatat gcagtgattt
    64921 ttgtttttgc cgggtcgccc cggctttttt attttactta caaattttga gtacaaaatt
    64981 tctacacttc ctcaaaataa ttgcacaata tgctaaaaaa atatgaatga catgctgttt
    65041 tattgttcat ataaatctta aaagcagaaa tttatctgtt ccccccttta aaaattcggt
    65101 gaataccctt acttattggt atactgaagt tgcttcagat aaaaacgcat tgaacctcga
    65161 ataacgttgt ctagtaacac gaattagggg gccatgatgg aaaaaaataa tgaagtcatt
    65221 cagactcatc cgctcgtagg gtgggacatc agcaccgttg atagctatga tgcgctgatg
    65281 ttgcgtttgc actaccagac cccaaataag tccgagcagg aagggactga agttggtcag
    65341 acgctctggt taaccactga tgttgccaga caatttattt cgatattaga agcaggaatc
    65401 gccaaaattg aatccggtga tttcccggta aacgagtatc ggcgtcatta acatgacatg
    65461 accatccacc caaaaggcac ctcaccggtg cctttaccat ttctgggttg tatatctgca
    65521 ttcagttaat tactctgctt aaaccatgag agcagagaga aaaaaatgaa atacgatctc
    65581 atcattattg gcagcggttc cgtaggcgct gccgccgggt attatgcaac ccgcgccggt
    65641 ttaaacgtgc taatgaccga cgcccatatg ccaccgcatc aacacggcag ccaccatggc
    65701 gatacgcgat taattcgcca tgcttatggt gaaggcgaaa agtatgtccc gctggtcctc
    65761 cgcgcgcaaa cgctgtggga tgaactttcc cgccacaacg aagatgatcc catttttgta
    65821 cgctctggtg tcattaacct cggcccggct gactccgcat ttctcgccaa cgtcgcccac
    65881 agcgccgaac agtggcaact caacgttgaa aagctcgatg cgcaagggat tatggcccgc
    65941 tggccagaaa tacgcgtccc ggacaactac atcggcttat ttgagactga ttccggtttt
    66001 ttgcgcagcg aactggcgat taaaacctgg atccaactgg cgaaggaagc gggctgtgcg
    66061 caactgttca actgcccggt caccgcaatt cgtcatgacg atgatggcgt aactattgaa
    66121 accgttgacg gtgagtatca ggcgaaaaaa gcgattgtct gcgcgggaac atgggtaaaa
    66181 gacctgctcc cggagctgcc tgtccagccc gtacgtaaag tatttgcctg gtatcaggcc
    66241 gatggccgct atagcgtgaa gaataaattc ccggcgttta ccggtgaact gcccaatggc
    66301 gatcaatatt atggttttcc ggcagaaaac gacgcgttga agattggcaa acataacgga
    66361 ggccaggtta tccattcagc ggatgaacgt gttccgtttg cggaagtggt cagcgatggt
    66421 tcggaagcct tcccgttctt gcgcaatgta ttgccgggta tcggttgctg cctgtacggc
    66481 gctgcctgca cctatgataa ttcgcctgac gaagatttta ttatcgatac cctacccggc
    66541 cacgataata cactgctcat taccggcctg agtgggcacg gttttaaatt tgcgtcagtt
    66601 ttaggggaaa tagctgccga ttttgcgcaa gacaaaaaaa gcgattttga tttgacgcca
    66661 ttcaggcttt cccgcttcca ataatcatca ttacggcctc cagaatgagg ccgtttttac
    66721 aggagtattt aatgcgtcgg ctgttgcact atctcatcaa taatattcgc gagcatctga
    66781 tgctttatct ttttctctgg ggattgttgg caattatgga tctgatctat gtgttttatt
    66841 tttagttttc cgcactgaca taaactgaca aatatttaat ctccctttca tttagcgtga
    66901 aaaattgaat gagattattc ctgcttctac agcactcacc agacatctct gatgctgaac
    66961 ccactaaact tatgaagatt ctttcattat taattcaaaa ttattgaaat aaaaataaat
    67021 atcattcaat ttgttatttt tgtgttgcaa ttcattctcc gacacgccat tttctttctc
    67081 tcgcaaattc gcattggatg cacttatgtc attcacaaat acccctgaac gctatggtgt
    67141 tatatctgcg gccttccatt ggctaagcgc aattattgtc tacggcatgt ttgctttagg
    67201 tctgtggatg gtcacgctca gttattacga tggctggtat cacaaagcac ccgaactgca
    67261 taaaagcatc ggtattttgt taatgatggg gctggttatt cgcgttctgt ggcgtgtcat
    67321 atctccaccg ccgggtccgc tgccgagtta ttcgcccatg actcgtcttg ccgcaaaggc
    67381 tggacatctc gcattgtacc tattgctgtt cgccatcggc atcagcggct atctgatctc
    67441 aactgccgat ggtaaaccga tcagcgtttt tggctggttt gacgtccccg cgacccttgc
    67501 cgacgctggc gcacaggcag actttgccgg tgccctgcat ttttggctcg cgtggagcgt
    67561 cgtagtactg tccgttatgc acggatttat ggccctgaag catcatttca tcgataaaga
    67621 cgacactctg aagcgcatgc tgggaaagtc gtcatctgac tatggagtat aaaaaatgaa
    67681 aaaaagcctg cttggtttaa ccttcgcgtc cctgatgttc tctgccggtt cagcggttgc
    67741 cgccgattac aaaattgaca aagaaggtca gcacgccttt gttaatttcc gcatccagca
    67801 ccttggctat agctggttat acggcacctt taaagatttc gacggtactt ttacctttga
    67861 cgaaaaaaat ccggctgccg ataaagtgaa tgtgacaatt aacaccacca gcgtcgatac
    67921 taatcacgcc gaacgcgata aacatcttcg cagtgcagat ttcctcaata ccgcaaaata
    67981 tccacaggca acattcacct ccaccagcgt gaagaaagac ggtgacgaac tggatattac
    68041 cggcgatctg acgctgaatg gcgtaaccaa acccgtcacg ctggaagcga aattaattgg
    68101 tcagggcgac gacccatggg gtggtaaacg tgcaggcttc gaggccgaag gcaaaattaa
    68161 gctcaaggac ttcaatatca agacagattt aggtccagct tctcaggaag tggatctgat
    68221 tatttcagtg gaaggcgtac agcagaagta agagtgaaat gttgccggat ggcacgcatc
    68281 cggcaatgat atttattccg ttggatcagg aatgcccagt gttgtattca gacgtccacg
    68341 agacttatta aagatcttat tgccattttc acgtcctgcc cgacggcgtc gctgttcttc
    68401 tggcggtaac gcgctttctt cgcagcaaat ctcactacaa caacctttgt atttttccgc
    68461 acatactgga cactgaataa acagcaggtg gcagccatca tttttacagt tggtatggct
    68521 gtcgcacggc gcgccgcact ggtggcaatg cgcgataatc tcatccgata tacgttcgcc
    68581 catccgctcg tcaaaaacaa aatttttgcc aataaaacgc accggcaagc cctgctcgcg
    68641 cgccttacgg gcgtattcaa taattccgcc ctcgatatgc cagactttgt tgaatccgtt
    68701 atgtttcatc caggcactgg ccttttcaca acgaatgccg ccggtgcagt acatgacgat
    68761 ttttttatct ttatgtgcct gcatcatctc gactgctttt ggcagctgct cacggaaggt
    68821 atctgccgga atttcgagcg cgttttcaaa gtgccccact tcatattcat agtggttacg
    68881 catgtcgata aatagtgcat cgggatcgtc aagcatggcg ttcacttccg ccgcttgcag
    68941 atactcacca acattgctgg catcaaagtg aggatcgtca ataccgtcgg caacaatgcg
    69001 atcgcgtacc ttcatgcgca gtacccagaa ggatttcccg tcatcatcca acgcgatatt
    69061 caggcgtaaa ccctctaaag ccgggtcgaa ggcatagagc tgcgcgcgaa atgtttcaac
    69121 attgctcgca ggtacgctga tttgcgcgtt aatgccctca tgcgccagat acactcgccc
    69181 aaaaacattc agcgcggtaa acagctgata taaagcgtca cgggtcgcct taggatcggc
    69241 gatgtggaaa tacttgtaaa acgaaatggt ggttcgcggt tcgctctcag ccaacatttt
    69301 ggcttttagc gcgtcgttgg aaatgcggtt gtgtaacact ggcatggtgt acggttcctg
    69361 cgagatggga aagtaaaaat ccgcggcatg atatagcaat tatcgataat taacatccac
    69421 acattttacg ctacatttgc gcattaaaaa ttatttgtta tttacaagcg cggcaatttc
    69481 gcccagtctt cagccacaaa ttttggttgc gggcgaaaaa atgcgacaat acatacaatt
    69541 gcccgaatag gttgaaaaac aggattgata tgacgaatct acccaagttc tccaccgcac
    69601 tgcttcatcc gcgttattgg ttaacctggt tgggtattgg cgtactttgg ttagtcgtgc
    69661 aattgcccta cccggttatc taccgcctcg gttgtggatt aggaaaactg gcgttacgtt
    69721 ttatgaaacg acgcgcaaaa attgtgcatc gcaacctgga actgtgcttc ccggaaatga
    69781 gcgaacaaga acgccgtaaa atggtggtga agaatttcga atccgttggc atgggcctga
    69841 tggaaaccgg catggcgtgg ttctggccgg accgccgaat cgcccgctgg acggaagtga
    69901 tcggcatgga acacattcgt gacgtgcagg cgcaaaaacg cggcatcctg ttagttggca
    69961 tccattttct gacactggag ctgggtgcgc ggcagtttgg tatgcaggaa ccggggattg
    70021 gcgtttaccg cccgaacgat aatccactga ttgactggct acaaacctgg ggccgtttgc
    70081 gctcaaataa atcgatgctc gaccgcaaag atttaaaagg catgattaaa gccctgaaaa
    70141 aaggcgaagt ggtctggtac gcaccggatc atgattacgg cccgcgctca agcgttttcg
    70201 tcccgttatt tgccgttgag caggctgcga ccacgaccgg aacctggatg ctggcacgga
    70261 tgtccggcgc atgtctggtg cccttcgttc cacgccgtaa gccagatggc aaagggtatc
    70321 aattgattat gctgccgcca gagtgttctc cgccactgga tgatgccgaa actaccgccg
    70381 cgtggatgaa caaagtggtc gaaaaatgca tcatgatggc accagagcag tatatgtggt
    70441 tacaccgtcg ctttaaaaca cgcccggaag gcgttccttc acgctattaa atctcccctg
    70501 ccggatgctt cagaatggca tccggcatta ccacagcaaa tccccctgat ttagcgataa
    70561 aagctctctg gattgcgccc cctggaagtc gggcgcataa ttagtgtgct tatcttttct
    70621 tcttatgttc accgcgcctg gcgcaccaac agcggattgc tatgtcaccc tgtgaaaatg
    70681 acacccctat aaactggaaa cgaaacctga tcgtcgcctg gctaggctgt tttcttaccg
    70741 gtgccgcctt cagtctggta atgcccttct tacccctcta cgttgagcag cttggcgtta
    70801 ccggtcactc cgccctgaat atgtggtccg gtattgtctt cagcattaca tttttatttt
    70861 cggccatcgc ctcaccgttt tggggtggac tcgccgaccg taaaggccga aaactcatgc
    70921 tattacgctc tgccctcggc atgggcatcg tgatggtgtt gatgggactg gcacaaaata
    70981 tctggcagtt tttgatccta cgggcgcttc ttgggttact tggcggattt gtccccaacg
    71041 ctaatgctct tatcgccaca caagtaccgc gtaataaaag cggctgggcg ctgggtacgc
    71101 tctccacagg cggcgttagt ggtgcgttgc tcggcccaat ggctggcggc ctgctcgccg
    71161 atagctacgg cttacgtccg gtattcttta ttaccgccag tgtgctcata ctctgctttt
    71221 tcgtcaccct gttctgcatc agagaaaaat tccagccggt cagcaaaaaa gagatgctgc
    71281 acatgcggga agtggtgaca tcacttaaaa acccgaaact ggtactcagc ctgtttgtca
    71341 ccacgttaat catccaggtg gcgacaggct caattgcccc cattctgacg ctgtatgtcc
    71401 gcgaactggc gggtaacgtc agtaacgtcg cctttatcag tggcatgatc gcctcggtgc
    71461 caggcgtggc ggctctgcta agcgcaccac gactcggcaa acttggcgat cgaatcggac
    71521 ccgaaaagat cctgattaca gcgctgatct tttctgtact gctgttgatc ccaatgtctt
    71581 acgttcagac gccattgcaa cttgggattt tacgtttttt gctcggtgcc gccgatggtg
    71641 cactactccc cgccgtacag acactgttgg tttacaactc gagcaaccag atcgccgggc
    71701 gtatcttcag ctataaccaa tcgtttcgtg atattggcaa cgttaccgga ccattgatgg
    71761 gagcagcgat ttcagcgaac tacggtttca gagcggtatt tctcgtcacc gctggcgtag
    71821 tgttattcaa cgcagtctat tcatggaaca gtctacgtcg tcgtcgaata ccccaggtat
    71881 cgaactgatt tttcgccttt catacttgca aaagcggaga atcagctatc cttttccctg
    71941 aaacctcatc aactcaaagg gagaatcgtg atgaccatgt acgcaacgct tgaagaagcc
    72001 attgacgctg cacgcgaaga atttcttgca gacaaccccg gcatcgacgc cgaagatgcg
    72061 aatgtgcaac agttcaatgc ccaaaaatac gttttgcagg acggcgacat catgtggcaa
    72121 gttgagtttt ttgccgacga aggggaagaa ggtgaatgtt tacctatgct tagcggtgaa
    72181 gccgcgcaaa gtgtttttga tggcgactat gatgagatag agatacgcca ggagtggcag
    72241 gaagagaata cattacatga atgggacgag ggggaatttc agcttgagcc accgctggat
    72301 accgaggaag gacgcgcagc agctgatgag tgggatgaac gttaatcact catacgggcc
    72361 atgatgaatg tcgatcggca gcagtaaagt atcaaaaacc agagagaatg gcagatcaag
    72421 gatcgtgaca taacgccagg cggagtcacg cacatcccat tgcacaccgg gataatattg
    72481 gttgccatgc ccctgccccg gtatagtgcg actaataatg ctgccacagc cactcagcaa
    72541 ggtcaccatg atgctcacca caattaaacg catttgatac ctctttcgta aaaaaatacc
    72601 ggcataacgc cggtattttt attggctcgt tgtttttgcc ggatgcggcg tgaacgcctt
    72661 atccgaccca caaaatcttg caaaatcaat aaattgcagg aacgatgtag gcctgataag
    72721 cgtagcgcat caggcaacta cgtttttatt gcgaagccgc atccggttta cgcaatgcca
    72781 gtggattgag ctttatccct tcgtaataac tcacccatga agaatatctc tccggggaat
    72841 tccagacgcg gaaatgcaga cgggccatcg tcaccggatc gcttagcagc accaggcgac
    72901 gatcgcgatt cagcttctct ggcgtctcgt tcagcgcctg ttcaacgtgg cggtcacggg
    72961 cgatttccag caccttactg gcgcggtgac gcgcggtcgc cattgcggtt gccagagcgt
    73021 taaatgacgg gttaaacact gcgtgcataa agccatcatc aagggagcgt tgacgattca
    73081 tctcaaggaa ccgatcggta tcaaccagca cctgcggcgg cgaatactct tccgggatca
    73141 ggaacagttt ccagcgtttg gtgcgcagac caacggtggc acggctggaa atcaccgaaa
    73201 caaacggtga caggatcaac gagaagacaa tcggtgccag ccagaacagg aaacgcagat
    73261 ccaaccacgc cataccaaca gcccacacta accctaacag cagctgtgag ccgtggcgtt
    73321 tgaacgcttc accccaggaa gtggagtcat catcacgctg cggtgaattc cacaccactt
    73381 cccagccaag gaacgcgctg acgacgaaga ccgtatggaa cagcatgcgt accggagcca
    73441 gcagcacgga aaacagcact tccagcagca acgataatgt aacgcgccag aagccgccgt
    73501 attctttcgt tcctttgcac cagataagca aaatgctcaa taacttcggc aggaacaaca
    73561 gcaccatggt cgaagcaaaa agtgcaatcg ccagctcagg acgccactgc ggccacaccg
    73621 ggaacaactg ccgtggttgc aggaagtatt gcggttcggt caacgcatgt actacctgca
    73681 atgcagtaga gagcgcgagg aacataaacc acagcggagc ggagagataa gacatcacgc
    73741 ccgtcaggaa taccgcacgg tgaaccgggt gcataccctt caccaggaac agacggaagt
    73801 tcatcaggtt accgtggcac cagcggcggt cacgttttag ctcatcaagc aagttaggcg
    73861 gcaattcttc ataagaaccc gggagatcgt aagcaatcca gaccccccaa cctgcacggc
    73921 gcatcaacgc cgcttccacg aagtcatgtg acaggattga accggcaaag gaaccttcgc
    73981 ccggcagcgg agccagtgcg cagtgctcga taaacggttt cacgcggata atcgcgttat
    74041 gtccccagta gtgcgactcg ccaagttgcc agaagtgcaa accggctgta aacagtggcc
    74101 catacacgcg ggtcgcgaac tgctgacagc gcgcatacag cgtatccata ccggacgctt
    74161 tcggcgacga ctgaatgatc ccggcgttcg ggttggcttc catcaggcgc accaggccgc
    74221 ataaacaatc accggtcatt accgagtcag catccagcac caccatgtag ctgtactggc
    74281 tgccccagcg acggcagaag tcatcgatat taccgctttt acgcttcacg cggcgacggc
    74341 ggcggcgata gaaaatctga ccttcgccac cgacttcagc gataagctcc atccaggctt
    74401 tttgctctgc gacgcagata tccgggttat aactgtcact aagaatgtag acatcaaagt
    74461 gtttggcatt cccggtggct tttactgatt cccacgttgc acgcaggcca gcaaaaacac
    74521 ggttcacgtc ttcgttacag ataggcatga tcaacgccgt gcgatgctcc gggtttaatg
    74581 gttcatcgcc aactgttgac gcagatatac tgtatttatc gcgaccaata agcagttgca
    74641 ggaagcccat taacgccgtc cagaatccgg cggacaccca acagaacagt accgcaaaga
    74701 ggatcaggat accggtttgc agcatataag gcagaagctg cataaaggaa acccacaaat
    74761 cctgaccaac catatccata ggattaatca gcgcccaacc ctgataagga agaatggtct
    74821 tcatatacca ggtcgcgacg acagtttgcg cgagcgtcag gatcaacaga atgtaacggc
    74881 ggatggtacc gacggtacgc cacttttgct cgctctcctg ctcttctttg gtcaaacgag
    74941 ccagatagcg cggcgtgaca tcgcgtccac gcaggcgatc ccagaaacgg cctaccgggt
    75001 tggtacgcca cgggtcggga aacatcgagg agcgttttgc ttctggcatc gccttcagct
    75061 gatcgcgccc ttcgtcgtct ttaattaact gtccatcagc aagtgaatct ggccaggctt
    75121 gttccagacg cgcctttacc gagccttgcg gggaatcatc ctcccgcgcc caggtgcggt
    75181 gttcggcatc cagcgcctga tgaacggcgc ggatatcagt cttcggcaat gccgctttct
    75241 cgcttgcggc gatgggcatt gcgtcaatgt actcagttgt cttattcatt ggcaggtaac
    75301 tggtagctcc aggtttcact caacgtctga tcggcattca ccagcgcagc acgcatttca
    75361 gtggttttct tggcatcttt cactttcaca cgcatcacca gacgccagcc tttggtaacc
    75421 gggttatagc gcaccgtgct ttcaactatc tcaccattat caccaatgct ggtttgcgct
    75481 gtgaccgggg tatcctctgg cagttttttc atctctgcgc cggtaaaatc gaccacaaag
    75541 gcgatagtac cgtcaggctg gcgaatcagg ttcgactgct tcacatcccc cgttgaacga
    75601 cgcgtttgtt gcacccatgc gttatctggc gcatgcagtt tgtcttcatc acggctgaag
    75661 gtgatggtgt atttaaagtt catctcttta cccggctccg gcagctgatc cggcgtccag
    75721 taagcgacga tgttatcgtt ggtttcatcg ttggttggaa tttctaccag ctcaacgctg
    75781 cctttacccc actccccttt cggagtcacc catgcgcttg gacgaagatc gtaacgatca
    75841 tcgagatctt caaagcggga gaaatcacga ccgcgctgca acagaccgaa gccttgcggg
    75901 ttttccatag agaagctgct gaccgctaaa tgtttcgggt tattcaacgg acgccagatc
    75961 cattcgccat taccggcatg gatagagaga ccgttagagt cgtgcaactc cggacgatag
    76021 ttatttgcag gcgacggttg gttcggccca aacaggaaca tactggttaa cggtgcaacc
    76081 cccagtttgc cgactttatc gcgcagatag attttcgact gcacatccac aaccgtgtca
    76141 cgccctggca taactacgaa tttgtaagca cctgtcgcgc gcggcgagtc aagcaatgca
    76201 taaatggtta aacgtttatc agtcggtttt ggacgctcga tccagaactc tttgaagcgt
    76261 ggaaattctt cacccgatgg caaggcggta tcaattgcca ggccgcgggc agaaaggcca
    76321 taaacctgac ctgcaccaat cacgcggaaa tagctggccc cgagcatgct gacgatttca
    76381 tcgtttttat ctttgctgtt gatcgggtaa agcactttaa aaccggcaaa accaaggtct
    76441 tttaccgtgt ctttgtcatg ctgaacatcg ccgaaagtga aataatccgg gctgtatttg
    76501 attcgtttga ctgcggtggc agtcacttca tttattttga ccggggtatc gaagtacata
    76561 ccctgatggt agaactcgag tttgaatggg gtcttcagat tgttccagta cgctttgtca
    76621 tgattaaact ggatctgctg atagtccgcg tatttcatat cgcggaaaac ggagggcaag
    76681 ttgcttttgg gcgcctcata gcctttcccg gctaaggatt gagcttgctt tgcgacatca
    76741 tcaatactga aagcccagct tgaagatgta tacagggtta acattactgc agcactcaac
    76801 caacgcattt tcatcatttg tagtttatgt ttcataatta gtaagcactt ccccctttgt
    76861 gtgcttatat cgatccgatc tattttaatg gataaccagc cattccgaca acagaatccc
    76921 ggtatcgttc agcacgctgg ctcatggatt aagcacctga ttgcaaccgt tttcactttc
    76981 cgtgcttctc ctaaagacag aagcatcgac ttcgtgtagg gtttgccagc aattttattt
    77041 atcaaccgtc ttacagacgc ttccattctg gttagtggta gcgatgatgc tatgcataaa
    77101 aaccttgaag cctgcgcctg gcgcggtcag gtcggtgtcg ctatggcaac aagcctaaag
    77161 gcataacccg acagggataa gacgaaaaat ccgagattag ttaaccatat atgaatccag
    77221 tacccgcgca acgtgaatat ttcctcgact ccatccgcgc ctggctgatg ttgttaggga
    77281 tcccttttca tatttcttta atctattcga gccatacatg gcatgtgaat agcgccgaac
    77341 cgtcattgtg gctgaccctt tttaatgact tcatccactc gttccgcatg caggtatttt
    77401 tcgttatatc cggctacttt tcctacatgc tttttttacg ctatcccttg aaaaaatggt
    77461 ggaaagtacg tgtcgaacgt gtaggtatcc cgatgttaac agccatcccc ttactgacat
    77521 tgccgcaatt tattatgctg caatacgtca aagggaaagc ggaaagttgg cctgggctgt
    77581 cattgtatga caaatataat acgttggcct gggaattaat atcacatctg tggtttttac
    77641 tggtgttagt ggtcatgacg acgctgtgcg tatggatatt taaacgcatc agaaataatt
    77701 tagaaaattc tgataaaacg aataaaaaat tctcgatggt aaaactatcg gtgatttttt
    77761 tatgcctcgg catcggttat gcggtaataa gaagaacgat ttttattgtg tatccgccca
    77821 ttctgagtaa tggcatgttc aattttattg tcatgcaaac gctgttttat ttgccgttct
    77881 ttatcctcgg cgcactggct ttcattttcc ctcatcttaa agccttgttt accacgccgt
    77941 ctcgtggctg tacccttgca gcagcattgg cgtttgtcgc ttatttactc aaccagcgct
    78001 atggcagtgg cgatgcctgg atgtacgaaa ccgagtcggt gatcaccatg gtcctcggtc
    78061 tgtggatggt gaatgtggtc ttctcctttg gccaccgttt gcttaacttc cagtcagcgc
    78121 gggtgactta ttttgttaac gcatcgctgt ttatctatct ggttcaccac ccgttaacgc
    78181 tgtttttcgg cgcatacatt acaccgcaca tcacctccaa ctggcttggt tttctctgtg
    78241 gcctgatatt tgtagtaggg attgcgataa ttctgtatga aattcatttg cgcatcccgt
    78301 tactgaagtt tttgttctct ggtaaaccgg ttgttaagcg tgagaacgat aaagcaccag
    78361 cccgttaagc cacatttaca ataaccattc cacgggcaat atcgacgcca gtctgaccat
    78421 aacccgcttc cagaaactgg tggcgggttc ttttttgaga ataatctctt tctttgcatg
    78481 acgatcaacc cagttgatcc gtccccacct gtccagacgg agctgccagg ccgcatcata
    78541 ctggctctga ataaagcgtt tatcaattaa ctgtgccagc gtttcgctct ctatcacgaa
    78601 gcccatttca gtattgagca atgttgaacg cggatcgaaa ttgaaagagc cgataaacac
    78661 cgttttacca tcgatgctaa aggttttagc atgcaggctg gctccggaat taccggttat
    78721 gccgcgatcg tgtaacgtac tactttgttc acgcgtcggc ttgagttcat ataattccac
    78781 gccatagcgg agcaattttt tgcgccagcg cgcgtatccg ccatggacga cagcaacatc
    78841 gttagcggca agagaattgg ttaggatcgc aatctttacc ccttttctca ccatccgtaa
    78901 gagttgcgcc acacctgcgc gtgtcggtac aaaataggaa gagataatat cgatgcgttc
    78961 actgggtgag cccatgatat cgaacaggcg ctgcggtaac agtgaatgcc gttttgcctt
    79021 gccctcccct ttcgccggat catcacttaa taaacgtgtt ttcgcccaga taagcggcaa
    79081 cgttccatca accagatgat ttataaacgg actggattcc attttgcgta agtaacgatg
    79141 cgtcatagca tcgttatgcc aggaggcggg taactcgatg cgatccgcca tttcaccttc
    79201 cgggacatcc agcacttgct gtaagggtga aaccgatttg caataccagt agcgggcgaa
    79261 atcatcggca acgtcctcta ccacgggccc tattgccata acatctaaat ccgaaaaaag
    79321 tggctcttcc cctgccccaa aataggcatc accaatattt cgccccccta ccagcgtcac
    79381 cacgccatcg acagtgaaac ttttattgtg catacggcga ttgagacggg aaaagtcggt
    79441 gatataacca agcggacgca gcaagcgaaa cgagaaagga ttaaaaagcc ggacttcaat
    79501 gcggggatgg ctgtcaagca agcgtaaaat gtcgtcaagt ccgggcgtat tgttgtcgtc
    79561 cagcaacaaa cggacgcgaa cgccacgctt tgctgcggct aacagggcgg aaaacagtaa
    79621 ccgacccgac atatcgtcct gccagatgta atactgaaca tccagcgtat gctctgccat
    79681 ttcggccaga cgataccggg cggcaaacgc atccagactt ttctccagag ggaaaagacc
    79741 acactgaccg ggatgttgcg aacacagtgg cagcaccgcg ctcgccagcc ggggcaaatc
    79801 attcatctcc ttgttgggta aggagtcttt cgtagaggtg ggcgttttct tcatcataac
    79861 agacaaagta tacctgttcg ggtaaagcgt gacgggtaat aaattctgaa acggttttaa
    79921 ctgcgatttc agccgctgcc gcacgagggt aaccataaac cccagtactg attgcaggaa
    79981 aagccactga cgtatagctg tttgccgcca ccagtcgtag gctattgaga taggcatcct
    80041 gcaaaagctg gtcttcgttt tgttcaccac cacgccagac tggcccgacg gtgtgcacta
    80101 cggctttagc gggaagagcg cctgcaagcg taataacggc atgccccgta gggcaatcgc
    80161 cctgctgttg cctgactttt aaacaggcat ccagcagggc cggacccgct gcgcgatgaa
    80221 tggccccatc gacgccgccg cctcccatta atgacggatt agccgcattc acaatcacat
    80281 caacggccag tttggtaata tcaccctgca caacatgaat acgcgttttc ataacgcctc
    80341 cttacacctt cttgtttctt aagtgtacag caggcttttt ggttaaatcg catttttctg
    80401 ctcagcaacg tgcgttgttc agaaacttag ttatattcga tgttcattac agccagcttt
    80461 ttctgtttat caagatactg cacttttact gaggctattt gcgcgttttt aacattaccg
    80521 ctcattaacg ctttgctgga ataggttttg cccggaacag aaccattctg tgggcagttc
    80581 atttctacgg gtgatgactg ggtgctgacg tcacatgccg gttccacaat ttggccataa
    80641 aaatggatca cccccccttg cgcggtgctt cctgcgatgg caataaaagg aaaaagcaaa
    80701 ctgccgagca taagagagtt taaaaaaggt ctgaacattt attctatttc ctcaatgatt
    80761 agtcatcctt gagggttgtg ttatccatac tttcaggttg gctgattcgc agcagaccat
    80821 tctctccaga ttcatcttat gctcgatatt tcaacaaatt aagacttttc tgaagagggc
    80881 ggccattgtt gtgataaatg aagtgactgt ccatcagaaa cagtaacaac tattttcacc
    80941 cgatcttccg gggaaatatt taaactcaac ttcgtcaaag caataggttg attagcaggc
    81001 aatgagaggg tcttttcttg cttcgtctga ctttgccctg aactgccttc gcgcagggac
    81061 aatatttgta ctctgcacag acaagattga gtaagagtga cttcaggaat aatggtatac
    81121 acatcccctt gctgggtcgt attaaaggtt atctggctgg aaagtgccgc aaggagtaat
    81181 aacgcattca tattcttctc ccgaaaaaaa acagggcttg cgccctgttt ctgtaataca
    81241 aatgatgtat tagtactgat gagcggtcgc gttgttacca aagccaacct gagtcacgtt
    81301 gacggaggag ttagatgcag tctggtcaac tgcagcaccg ttgccaccac cgaactgttt
    81361 aacagtcatt tcagaatttt tgccgttcca ctgatcaaga gtggcgctgt taccgaagcc
    81421 acgttgggtc agatcgattg agctgtcatc tgagccctga cctacatctg caccattacc
    81481 accgccatgc tgggtaatag tcaagtcaga gttacgggca tcagtttgca gagcaagtgc
    81541 agagttaccg ccaccgtact ggtaaatgtt cagctctgaa tttgggccgc tattattacc
    81601 gccaccaccg tggttaccgc cgccgccgta ctgaggaaca acacctgcca gagcgctacc
    81661 ggagaatacg attgctgcaa ttgctgctac ttttaaaagt ttcatgtaaa acccccatcg
    81721 gattgattta aaagtcgaat ggaaattaac gttgtgtcac gcgaatagcc atttgcgact
    81781 gtctctgcac tacaattgcc gttttttgag taccatactg tgtaatattt gctttattac
    81841 cagaaccttt ctggataatc atcgcagtat taccataagc accttgcgaa atactggcat
    81901 cgttggcact gcccgcctga tcaatatatg caaggttata atctcctgtc tggtcaatct
    81961 ttgcccggtt gctactacct tcttgcgcaa caaccgccaa aagttttgag cctccctgcc
    82021 gtaactgagc actattattc gtcccagctt gaccaattat ggctgcctga ttaaatgaag
    82081 acttactcaa ttcatttacc gcgaagttat attctgaatt agctaaatca taacctgctg
    82141 cggctgcaat cccaggcgca cccagtattg ttaacatcat aaataacaat ttgtttttca
    82201 tgttgtcacc ctggacctgg tcgtacattt aagaaattaa atcatttcaa cttggttgtt
    82261 aacgcaacct gtattttgtt aacgctgcgt tacgatggaa agtatgtctg cggaaatatt
    82321 tttaataact cacccgcgcg ttgtattttt ctttttttgt tcataccaaa gtattaaaac
    82381 ccacgtaaat acggtgttat ctacgcaaaa aatattttgt tttcttttaa atctccgttt
    82441 tccgctatca aaaatcacca gacagtcatt tttcttgccc gtcgctgatt gctgcgatat
    82501 gtcttgcgca caagccgtga caaacctcgt ctttttgcag taaaaaattg tccacggagg
    82561 tgcggagaaa aaacaagaac gttttacatg acgaaaggac tacaccgaaa tattttttat
    82621 atgtattatt agtaagttat caccatttgt atgatttttt aaaattgtgc aataaaaacc
    82681 aaatgtacaa cttttctatc atttctaaac ttaataaaac cttaagatta acattttaat
    82741 ataacgagtt acatttagtt acatgtttaa cacttgattt aagatttgta atggctagat
    82801 tgaaatcaga tgtaatccat tagttttata ttttacccat ttagggctga tttattacta
    82861 cacacagcag tgcaacatct gtcagtactt ctggtgcttc tattttagag gcagctgtca
    82921 ggtgtgcgat caataaaaaa agcggggttt catcatgttt aatgaagtcc atagtattca
    82981 tggtcataca ttattgttga tcactaaacc gtctttgcaa gcgacagctc tcttgcagca
    83041 ccttaaacaa tcgctggcaa ttacaggaaa attacataat attcaacgtt ctctggacga
    83101 tatatcttca ggctctatta ttcttctgga tatgatggaa gcagataaaa agcttatcca
    83161 ttattggcag gatactttga gcaggaaaaa caacaatatc aaaatattgt tgctaaatac
    83221 gcctgaaaat tacccgtacc gcgacattga aaactggcct catatcaacg gcgtttttta
    83281 tgccatggag gatcaagaac gtgttgtcaa tgggttgcaa ggcgtcctgc gcggcgaatg
    83341 ctactttacg caaaagcttg ccagttacct gattacacat tctggtaact atcgttataa
    83401 cagcacggaa tcagccctcc ttactcatcg ggaaaaagag atcctgaata agctgcgtat
    83461 cggcgcgtct aataacgaga tcgctcgttc gttgttcatc agcgaaaata cggttaaaac
    83521 gcatctttat aatcttttca agaagatagc cgtaaaaaac cggacacaag cggtttcctg
    83581 ggcaaacgat aacctcaggc gataaagcca tgaaacgtta tttacgctgg attgtggcgg
    83641 cagaatttct gttcgccgca gggaatcttc acgccgttga ggtagaagtc ccgggattgt
    83701 taactgacca tactgtttca tctattggcc atgattttta ccgagccttt agtgataaat
    83761 gggaaagtga ctatacgggt aacttaacga ttaatgaaag gcccagtgca cgatggggaa
    83821 gctggatcac tataacggtc aatcaggacg ttattttcca gactttttta tttccgttga
    83881 aaagagactt cgagaaaact gtcgtctttg cactgattca aactgaagaa gcactaaatc
    83941 gtcgccagat aaatcaggcg ttattaagta cgggcgattt ggcgcatgat gaattctaaa
    84001 taaaaaattg ttcggaggct gcaatgcgtg tcaaacatgc agtagttcta ctcatgctta
    84061 tttcgccatt aagttgggct ggaaccatga ctttccagtt ccgtaatcca aactttggtg
    84121 gtaacccaaa taatggcgct tttttattaa atagcgctca ggcccaaaac tcttataaag
    84181 atccgagcta taacgatgac tttggtattg aaacaccctc agcgttagat aactttactc
    84241 aggccatcca gtcacaaatt ttaggtgggc tactgtcgaa tattaatacc ggtaaaccgg
    84301 gccgcatggt gaccaacgat tatattgttg atattgctaa ccgcgatggt caattgcagt
    84361 tgaacgtgac agatcgtaaa accggacaaa cctcgaccat ccaggtttcg ggtttacaaa
    84421 ataactcaac cgatttttaa gccccagctt cataaggaaa ataatcatgc agcgcttatt
    84481 tcttttggtt gccgtcatgt tactgagcgg atgcttaacc gccccgccta aagaagccgc
    84541 cagaccgaca ttaatgcctc gagctcagag ctacaaagat ttgacccatc tgccagcgcc
    84601 gacgggtaag atctttgttt cggtatacaa cattcaggac gaaaccgggc aatttaaacc
    84661 ctacccggca agtaacttct ccactgctgt tccgcaaagc gccacggcaa tgctggtcac
    84721 ggcattgaaa gattctcgct ggtttatacc gctggagcgc cagggcttac aaaacctgct
    84781 taacgagcgc aagattattc gtgcggcaca agaaaacggc acggttgcca ttaataaccg
    84841 aatcccgctg caatctttaa cggcggcaaa tattatggtt gaaggttcga ttatcggtta
    84901 tgaaagcaac gttaaatcgg gcggtgttgg ggcaagatat tttgggatcg gtgcagacac
    84961 gcaataccag ctcgatcaga ttgccgtgaa cctgcgcgtc gtcaatgtga gtaccggtga
    85021 gatcctctcc tcggtgaaca ccagtaagac gatactttcc tatgaagttc aggccggggt
    85081 tttccgcttt attgactacc agcgcttgct ggaaggggaa gtgggttaca cctcaaacga
    85141 acccgttatg ctgtgtctga tgtcggctat cgaaacaggg gtcattttcc tgattaatga
    85201 tggtatcgac cgtggtctgt gggatttgca gaacaaagca gaacggcaga acgacattct
    85261 ggtgaaatac cgccatatgt cggttccacc ggaatcctga cagataaaaa agccggaatt
    85321 atcatccggc attttactgt ttaagcgaaa gcgtgagtgc ccctcacgct ttatttttga
    85381 tttcctgctc acggtgagcc gtctttgcac tacgcgccgc cagccacagg ccgctgtttt
    85441 tcattgcgta accaaatacc agcccaagcg ccagcgaagg taacaccagt ttccagtcac
    85501 cctgcccggc aaacgtcgcg catgcgccta taaacgtccc cggaacaaat gaaagcagca
    85561 gctgtttggc ctgaatacac atcagaaacg cgacaatacc ggttatgaca taaccgagaa
    85621 tttccagatg tggtgccagt gcactaccgt aaataatgac catcgcccac accacgccac
    85681 taagcagggt tgcagcggag atcgccagcc ctttcagccc accttgcggg caggcaaagt
    85741 aggccgtaca gcccaggaag cctgcccagc ttagtaagcc cagggaaaca gccacccatc
    85801 cccagatacc ggagagaatg cctgttgtga ttgcaataga gagaagtatg ttcatgccgc
    85861 gcatgatagc agaaaacgcg gccatgaatg agatcgagca cacattttat gcaacaacaa
    85921 attatctgtt gcagttatga gtgacgatga tcacatttac tcttcagaat cttcttccag
    85981 ctcgtcccac attgcactaa tggcatcacg ggttagcggt gccatggtgc gccagaaagg
    86041 cgtggttgca tgggcctcca ctttgccgag gaacgcacca caccagggta acagatactc
    86101 actgaacagt gtttccagtg cttcgctctc atcttccgtt gactgatctt ccagccagga
    86161 agccgcaagc agcaatgtgc cgatgtgatc ggctggcgta tccgccagtg gcatccctcg
    86221 ttcggaaaga aaagcgcgca cttccgcttc cgttgcgtcc tcaacccatg cgctacgata
    86281 tggcggcacg gcacattcat cgccgataaa caacgcattg taatcggcag agacttgcgc
    86341 catatcacag cttttctgta aacgcgtcag taactcatcc tgctccagtg gccagttcgc
    86401 agccagtttc ccctcacgaa tcagggtaaa cagcggcacc agtaaaggat cttgcggttg
    86461 gcggtaatag agcgaaccca gcacacgaca gaggatagaa aactcgttca ttaatatatt
    86521 tccattacta gtaattaaag gtctgcaaat tccgcaatcg gtgccatacc gcgagattca
    86581 aggaagttca gtaagcggcg cggagaaaca ttcaaaatgc gctctggcgg aaaatctacc
    86641 gcgtcgagga ttttaagaca ctcttcaaat tcccccatgg taaacgcggt gtgagaatcc
    86701 gagcctaatg ccacccaacc tccagcatca cgtaccgctg cggctaccgc acgacagttg
    86761 tcttcactgc ccttacgtga gtgtaaaaat gaagaattat tgatttccag cgccacctga
    86821 tgtttcgcgg ctgcttcagc aacggctttc acatctattt catatttggg attccctaat
    86881 atcatgtacc cacaataaca cgagggggta caacaatgaa catcggtaaa gcaatcatca
    86941 actacgcagc acgtcgcaac atggacatta ccttgattgg cgatgagacc gtagcgttct
    87001 gggaagcgga taacgattgt gaatggatgt tctcctacat gattggtaat gatggtttcc
    87061 tccactttaa aggcaatgtg tatctgccgc aggagattaa agaagaatta ccggcgtgca
    87121 tcgatacaga caagaagctg aaagaagtaa tcaactttat cgctaaagag tttatcagca
    87181 agaagtaagg cagcaaaaca atgttcaata tcatgattcg taaatttggt gagatgactt
    87241 tcgagaaagc tggtgttgcg cgtaccgaag aagaagcaat ggccttagtt ctggtagcac
    87301 tgagatcatc acctgagatt atcgacgctg aatatgttgc ggctgagggt gagattaaag
    87361 agattaaagc ggtggctaag gaattaggtg ttaaaggttt ccgtaagctg aaactatccc
    87421 gcgagtcata tgtaattggt aagcaaggac aatacctaga tgagaatagc gcgattgtcc
    87481 tactgaataa gatcacccgc tatggtttcc agattgagca atataaaacg tgtttcgaat
    87541 tatacgaaaa aggtttgctg gatactctga ccatcgttcg cgcttaatta atttctaatt
    87601 tggtgggtgc aattcccacc gctttttaaa ctggagaatc aaacatgtta gcttttatct
    87661 cattcgtggg aggtagtctc acaactatga ttagtctttc ttatcttgtc gttagtatgg
    87721 ggtgagcaat gaaacaattt catgatggca tttcatctaa gacattcaag aaagaatata
    87781 gcggattgtg tattaactgg attgatttga ttggtgcggt tgtgtttggt ctggtaatta
    87841 gcatcaattt ttaacgatat aaatatatcg taattcaaat aacaagagga aattctacta
    87901 tgaaaaagat tatcgcgggt gttgttcttg ctctgggttt ggttggtgct gcgaatgcta
    87961 atacctatac ctattatgtg tgcaattcct acttcgaata taaaggagat gatacacgct
    88021 acctgagtga tggcgaccgt tattatcatg caccgtctgg caaataccgt ggttttatcg
    88081 gtgtgaaagt tcgagtgaat gatgataata gtcaatttgc tttcaacgat ccggtatatg
    88141 ataagacaat caaaagcccg aaactgaaag aagataagaa cgagaaagaa gaatattatg
    88201 gttccgaaga tggtaaatcc tacatcaaat atctgcattc tattgatggt tctcctatat
    88261 ttgatgttaa aaaaggtgat acgtcttatt ccctgattag ctgccgtgaa attctttaat
    88321 ctttaatcac ctagccccta tcgttataat acacggtagg ggcgtttttg tttggaaatg
    88381 gtatgaaaac taaactgtat tcgtatattc gcttctcgtc tatgcgtcag aatgatggtt
    88441 cgagttatga acgacaaatc aggatggcga gagaggttgc ggcaaagtat gaccttgaac
    88501 tggtaaatga ttatcaggat ctgggtgtat ctgcgtttaa gggtgctaac tctaaaacag
    88561 gggcgctatc tcgtttcctt gatgcaattg gtagatccgt tcctgttggt agctggctat
    88621 tcattgaaaa cttagaccgc ttatcccgtg ccgatattgt cagtgcgcag gagttattcc
    88681 tttcaataat ccgtaggggg ataaccattg ttactggcat ggataacaag atctactcgc
    88741 tggatactgt taccgctaac ccgatggacc tgatgttctc catcctttta ttcatccgtg
    88801 gtaatgagga aagccagact aagcgcaatc gtactaattc aagcgcacta attaagatta
    88861 aatcgcatca agaaaatccc cagaatccgg cagtggcaat cgaggaagtt ggaaagaata
    88921 tgtggtggac tgataccact tccggttatg tgttgcctca tcctacatac ttccctgttg
    88981 ttcaggagat tgtggaatta cggaagaatg gacgttcaac cgccgaaata ctggatcacc
    89041 ttaacgagac atatgcacca ccaccagcag taagcaacaa gaagcattca aaatggtcac
    89101 gggcaatggt tgaaaggttg ttccataccc gcgctttgat tggtatcaag gaagtctctg
    89161 tagatggcgt taactatgag ttaaaggatt attaccctcg tgttattgat gatgctacgt
    89221 tctatcacct taagaaaaat attggtgcta gagcatggaa ctttggagac aaggaagaag
    89281 ctaaaccgat ccccctgctt agtggcattg gcctattgaa atgtgatcat tgcggttgcg
    89341 ctatggttaa agtgaaggga acaaacaaac gttctgacca gtatcgttat acatgtgatg
    89401 cgacccgttc acgtagactt gattgcgagc atccaaactg gagttttcga ggggatcaat
    89461 tagagaaagc tgtattgcaa ttgctggctg ataaaatctg gattgctgag gataaggcta
    89521 atccggttcc ggctttgaaa gtacaggttg atgaaatatc acgcaagatt gataacctga
    89581 ttgccctttc tgctatgaca ggagcaacga aggagctagc cgatcagatt actaccctca
    89641 atagcgagcg tgaaacactc tacaatcaga tcaagatggc agaagaggaa atgtattctg
    89701 tggactctca aggctgggag aagctcgcag aatttgattt agaagatgtt tataacgagg
    89761 aacgactaaa ggtccggttt aagattaagc aagctctaaa gcggatcggg tgtagcagga
    89821 ttgacagaaa caaaaacttg tttgtactgg aatacatcga tggaaagacc cagagagttg
    89881 taatagaaaa ttcaagagga acgaggaaag gccggatatt cattgatttg aaaactatca
    89941 atgatagaca gattctggaa agtaacgggc ttgttttgca tccatgttta gacatgctga
    90001 cagataagaa ctggaaacca gaacaggaaa taccaggtcc attacaggaa tttggaattt
    90061 aagcggccta aatcgacgta taacaagcta aacactttaa ggggtacatc tgtacccctt
    90121 tttaatttaa ttgtattaaa gagcctctaa agggcttaaa tcgagttcta agtcttccgg
    90181 tgttaactca gctaacggtg ctttcatcca ctgcgataaa tctcgttcta tgtcttcatc
    90241 actaatgtag ttgttcagat tgattgcgtt ggtatcatca aaatacattg gcttagatgg
    90301 gttggtgtgg atgtattcat tgatgaatga tttaacatct ttcagcttgc taatcggtag
    90361 cgtttctgtg aatccgctat tcattacctt acgtgggatt ttcttgccct gaatattctt
    90421 tttaatcccc atttctaaat caccagcttt ccatccaatg ttaaacaaat gtgagcattc
    90481 aaaggtgatt ttctcgctgg tgtgcttctg gtgttctctt acccgttgca tcggatcttt
    90541 gcgagtggta attccatatt tgaaaaactt ctcgccaaca cgaattagat aaaagtgcat
    90601 agggcgctgt gcaaacttgt ttctgataac ctgttttcta ccattctgaa tcgatttaag
    90661 tacaccccta accaaagggc atgttaaccc gccttgtctg cggttattgt gtaaatcacc
    90721 tttcttgtga atctttccgt ggcacttaca acgaagaatt agtttagtgt caacaccctg
    90781 ataaggttca gccagaccta acacatccca ccctatcggc ttgtagaact tgcgagcgtt
    90841 ttctaagtgt tcttcttcgg taaatctaaa cttcttctta ggcggtgata ctctatcttt
    90901 gccagtaaac tgaccagtta gaacatgact aatacatggc gttttaacct ttccgttaac
    90961 ttctatgcaa actttggtgt tctggaatgg tttctttaca ggaagcacaa aaccactgta
    91021 taaccatcca tgcacttgac aaactttaat gattctggtt tcatattcga ccggaggggt
    91081 cgcacgtttg ctttttgcgg taaattcgat atcctttgct aaagtagtat tcatagtagt
    91141 gaatcctcaa taaaataata ttcactacta tttataagaa ttaattattg tagttttgga
    91201 aaccagtaag atcacaaaat gaatcagtgt catgtgctgg ggaacgatgc tctgcttcgt
    91261 cagagaaaat gttggctacc ggagattcca ctttaacttc cggcgcttct tcaacatctg
    91321 acttaacttc ttcgaccact ggttcaactg ctggagattc ttcttttgtt tcttcaatga
    91381 cgatctcagg ttctttcatt gcttcaacca gagacggatc aacttcgtcg aataccactt
    91441 tatcatctgc ggtgtctgct gccagaataa ggtcgttaat gctggttccc tctgccggag
    91501 tttcttcttc catttcggaa gccagtttag ttaattcggt ttctacgaac tcgaacatca
    91561 acattaaagg taatgcctat aagataaatt aagtgaggtt tttatgatga atgatgtgcg
    91621 caaagcatgt gatatcccgt tcaattttat ccgcaccaaa aatggcaaag cgccatcaca
    91681 tccaattgat atggaagcaa ggatcgtgac ccgtattgaa aacgagggtt tacccttgat
    91741 ttaccacgga ttcaaaggtg agtataaatc aatcaatagc cgtattgtgc tagagtgtga
    91801 aagctgcgca agaatcagag atataactgc aaaacaattc ttacataatc ctactgtgtg
    91861 cccgtgtaat cgtagcaaat atgacaacaa atataaaaag ggacaaccag tattatatgt
    91921 tatgcgttgt ggtgatgtgg gtaaggttgg agtaagtcac aatgtgttga agagaaaaca
    91981 taagctaaga tgccagaata agatgaaatt tgatatcatc gaggctttcg aatttcaaga
    92041 cgaaaaagac gcatacgcgg cagaattgtt tatcaagaaa aacctagtaa aaggtgattt
    92101 tgatattaaa gaaggtgcta cagaaacgtt tgtttataat gaaaaaatgg tcagaaatat
    92161 agctaacgtc gccagcatat tctaacaaaa aagcgcccac tggaggcgct ttaattttat
    92221 ccattccatc gtgatttttt tgatctggaa tcaatatgcg taaaggtttt atattttcct
    92281 aagccgtatt gagtaggata tttcccatca agataagcat gaacaatatc aggagaaatt
    92341 cctttcactg atatgtcagc cgcacggcct cgaacatgat agctattggt tgcaccgcca
    92401 acattcttgt tatgagtcgg gcaacggttg ccactgttaa taatcactgg tttaccgaag
    92461 tgctctcgta catcctcaag aatcaccagt aattcagcgt cgattgtatc ataatcacat
    92521 tttccgcatt tacatttaaa ttccttgcga gaaaaatgct tacttaacat attaccccct
    92581 tagatcattt cgaagatata accaataaag cgcataccct tgatataata aggagcagtg
    92641 cctacacaca ccgcgcgtgc atcgcccaga cagttaaagc tataaggatt aaccacatca
    92701 acttcttgtc ctacacgaaa acgatactta ggacgtttag ccaatgtagc gacacaaaac
    92761 acggtccctt tttcatggtc acggatacat tctttatatt gtttatgttt aactctcttc
    92821 gcctcaaaat catgtgtcat agattctggg ctaatgccat taataaaaat accggaaagc
    92881 tgatcgaccg gataagtagg aaattcagtg aaaatatttt tagccatgtt atacccccat
    92941 aagtttctat gagggtattt atggattaaa cgtatttcat gcgcgattta atgtgcttat
    93001 tgatgttttc aagcatcatt gcttcgttgc tttcccacga tcctagcgtc gaataacgag
    93061 tagaaatttt atccgattta acggcaacaa ttcgcttgct ctgtttctgt atgcgtttct
    93121 ctaagcgacg ttttgccacc gccgatccat tcctagcgcg tttggttcgg gatttcttag
    93181 gcttgtactt cttcatgata aaagtccctt ccttgttctc taccttgatg aagttgccgt
    93241 tttcgaggtt acgcatcatc ttaccgcctt tgatggcctt aatgttcccg tgggcgtcta
    93301 agaccttgcc gttagcgatt ggaactagct tattgatttt gccaccatcg aaatagtgtt
    93361 tcagatagtc atcctgactg ccgatcttct tgtccttatc ccttgcgccc ttgatgaaga
    93421 tttggtgtct cgtccctgat cggttcttgt agttggtatt gcctaccgct tgctgagtcc
    93481 atcgagtagg tctatcaaca ttcttgttaa tcttcttctg gagtgctctg gaagcaaaga
    93541 tcgccccttc ccctagtgcc ctttcgaatg tatcggttgc cttttcagac cattgccgta
    93601 acgctttctt agtccttaga gcgtttcgtt tattggtact ggttgccatg ttagccccct
    93661 aataacgaaa agacccccgc cagtgtcctt agcaattgtt catccacggt catagccggg
    93721 agttcaagtc caaaggacgt aagcagaggt ctaattgcta cgttataagt gagggcgaca
    93781 atcaagagat aaccaaaata tttcttaagt ttattcttca tatattcacc cctttattat
    93841 tatttttgtt tgagtatgtc gagaacttgg tcaaatttgg cgtccatcgc aaccactttc
    93901 ttctctatac cgtgtagtgt ttgttccatt tggtaaacac gttcagcaat ctgagtatgg
    93961 ttattctgca tcgtctcaaa cttctggttt aacaatgcgt cgctggattc caatttagat
    94021 aacctatttt cagttgctaa ttgatttcgg tgaagtctcc aaagaccacc acaaattaag
    94081 gcgataacac cgataccgcc atatataatt tcagtcatta cgcccccgat atttttataa
    94141 tttaatggca gaattattta gataaaaata atcccgccta acccaaaaga attaagcggg
    94201 attaattatt agaattaaat tttaagaaac agaaataccc gtagcggctt tcttagttac
    94261 cattaccgtt agatcgctga tatatgcact tgggttatag ttgttaacgc ccttacagta
    94321 aacttcaaaa gtcattgtta ctgccccgtg tccggctggc atgtcaataa ctccactgta
    94381 catacagcca gaagttgcag tgcgatcata tagaacacca ccatttttct taacgattag
    94441 tcggcaagta tcccaatgat cgctactttc gccacgacga acagacccgt tatgatgaat
    94501 cgctggaatc actatttggc gatcgaatgg atgatcatct tcgaccctta cagtgattgc
    94561 accatcaggc cagtttggtt ggcgatgcgg gaaactccta ccaaccactt tcacgaagtc
    94621 accacgcacc tgattagcat caagcatacc caaaatgcgg caacttgaat taatcgttac
    94681 gttgttcatt tcgccggaat cagccaccaa atgaccacga atattagcgt gtctaaaatg
    94741 acaagtgcca tctttgccga tataccatcc atcgttacca ttccagttat aagactggat
    94801 atagttacca attttagcat tatcgataga gccatcaata atatgacctg ttccgatctg
    94861 ggcgtgctgg atgtgagcac cgttaatctg ggctgtgccg attttagccg tggtgatgct
    94921 agcatcgttg atctgggctg ttccgatcgc cccattacga atcatggcat tatcgagata
    94981 aaccttgtta ccttcgatac caaacggaca aacttctgat ccgtcttgtg gagctaccgc
    95041 gattttatca gccgtaaaga tgattcttgt cggttctgcc ggatcattgg ttgcgctcat
    95101 atgaatacca gccacgcgac catctgcatt aactgccaga ttatatttgc tgttaatggt
    95161 tcccttcaaa gcatcgattt ttacatctgc ttcctgattc acaccagcaa tcttgccatc
    95221 catttctacc cgaacttgat caatcttact tgcgcttgct gcctcgctgg tagcaattgc
    95281 ttgtttcagg gtagtagcgg atgcgctaac ttctttggtg atatcgcctt tcagttcagc
    95341 tttaacctga tcaatcttag ttgcgctggc ttgctcactg gtagcaatca gactcttgag
    95401 agtatcggct gaggcttgga ccgtctgccc tgtctcggta gtaatctgtt tatgcattgc
    95461 atcaatctta gcatcggcat tagcgccagc ttgagcaata gcatccgcga tggtttcatc
    95521 taagcgatct tgtaaaccaa tcaggtcttc cagtgcttct ttgtcctgat cgtcccagct
    95581 aatggtagat ttcatttgca tgaaatacgg ttcagaccaa acagcatcat ccataccgaa
    95641 aatatcgtag tgagcaccac ggatataata atcaccgtca gccaaatcaa aggaagtatg
    95701 actaacgcta ttggtagtca ctgcccttgc atcggagaaa gtgttatcgg ttgcatactg
    95761 aatgattgac cctgcatagt catgttctac gtcatccgcc cagctaacaa acgcagtatt
    95821 aaagccacca cgcgcactaa aacctttcat cggcttatgt tgtgggttga tagccactaa
    95881 acgcgctggg gcgctctctg agttgttata gcccttaacg gatacttcta ccgtcaattc
    95941 acgggaaagg ccgttaaact ggttcatatc aagcgtatag gtccatgatt caggatcgcg
    96001 ggtacggtac tgaatagact taccagcctt gttagttacc ttgataatgt aggcttcaaa
    96061 caggtcgcta aacttgttag cttcgccgtt gatcatcaca tctaattgtt gctgattttc
    96121 ccattcgata atcagatcat tgccttcgaa agtaccaggt gaactaccct gatttttgat
    96181 gcggatcact ggcgtaggca gttcataggt aacttctgga ttctggttaa ccagttccac
    96241 ccattcggaa cgagcaataa taccgaaagc acaaacgcgg taatcgtagg agcgatcttt
    96301 tgccagtgca ttgatattga aaatttgctg tgaagtctgt cccagcttaa tccagttagg
    96361 tgatccactt acacggtaat caatctggaa accgtagcgg ttgaaatctt ccggtgcatc
    96421 ccatgtcaaa gtaacgtttt taccgtggat tgtctcacca gttgccttaa ttctgaaatt
    96481 agtcggtttc tgtactgtca ttgaatccgg taaaccggta ggtctattgt ctggagtcgc
    96541 cgcatagttc aggtcagtat aaacctgaga attatattct gtggcggtga tagtcatcat
    96601 cccagcaata ccagaatcaa tcgagcgatc aattgcagta atgcgccaaa gtgaattatt
    96661 cagtttcaat tcatcatagg taacgctaat aacatcccac acttcggcag tgaatgcgtc
    96721 agtagtcata aagctgataa cctgagtgat acgagattta tttcgctcaa tgctcgcgag
    96781 tttatcaatc tgatctttag acttaacgaa acgatattct acatccttag caataattcg
    96841 accatctgcg cgaacagtag catcgttttc agcatcagcc ggataacgta gcatttgctc
    96901 tgaatagtca attgatggtt cttgatacat cgcgttaatg gtattgaaat aaccgttagt
    96961 gccacctgtt ttcagtgata ctttacccat cataatattg tcttcattga aggtatgctt
    97021 aacaatatca ggagcatcca gtttcagggt aattcttccg aaggattcga acatcacccc
    97081 gccgaaagtc tgcataagac tggtcaagtt ctctttaaag ctggcgttcg gatcacatgc
    97141 accgtttgaa tgcaaatcca tctggcgtac ttgcttacgt actttcagga atgaatcaac
    97201 gttaatgttt tcaattggta cggataagcc atatttttca tttgttaggt agtggaaaat
    97261 ctgatccacg ccgttagtgc tagcctcaat agcattggtt tcgaggttac ggatttttaa
    97321 gcccataaca tcgaccgcta cctggctatt aggctggaga atatcaacac cagcagccaa
    97381 agatttgtca tcacgacgta aaacaataca catggtcgca atgccgttac cctgataccg
    97441 atcatcccaa tcagcgccca aatgatgttt agcaagatct aatgcagtgt taggattttt
    97501 acccgtgcga aactcgactt ctaacacttt gcgatattcg tctttaatgt ttcctttatc
    97561 gagaatgcca tcacgaattg tcatattctg actaatgaga acatttttat tatcgatgtg
    97621 cagtgcttta aagtgatcga tctcaccttc ggcaatagca aaaatttgta ccagtttgtt
    97681 attttcacgc tgtgaaattg ctttgtaaac gcagattgca ccagttcggg tagtaccgaa
    97741 aagaacgggt aatactgtct taggatcgtt tgatgttcct agtgtcaccg cattatctgg
    97801 gctttgtact ttcggtgttt ttggtgcgcc tacagtggaa gcgatcaagg tcattgcacc
    97861 agcagccata ccgatagcga ctgcggtcat aacagaaaat gttgcggctg ccgccatccc
    97921 cgccgaagca ccagcgatca ccgcgcctac caatatttca aatcccatta ttcacccccg
    97981 aatctataaa cttgttcata gtcaatgtct gaaacaggaa tggtcatcca gataccatct
    98041 tcttcaacga ggccataacc ggaataatga ggaactacgg aataatattt gcggtttcct
    98101 aatttgtggg ctgtgaccag taagtcgccg tcctgtaaat catcagtgac taatttgaaa
    98161 tgtttcttta ttggttgaag gatgtttgaa tatccgctta attctttgca gattttcaag
    98221 ccttcttctt tagttgaata ttttttataa agagaattat ataggtcagt accagcgaga
    98281 atatcgatga tcttacatgc aatgagattg caatcattct cgccttgaac gaactcctga
    98341 cctattaaag aattgatgta atcggtgata agcctagttt ttagcatgtt gaatacctcc
    98401 atgctgttat ttactaggct tagggagaag ggattatttc ttagagctaa accacttgct
    98461 ttcgctattc cacttcccgg cacgggagaa gaatagatcg ttctcgtttc caacatagga
    98521 tcggtggata ccatcggagg catgactacg agcgttttta tctagaactt cccagatact
    98581 attaagctga aattctgatt cgtttttaca ctcatcatct tcatgttcga tgttaatacc
    98641 gatggaatcg actaccccac ggaaaacagg gtaagtggtt tcaaccttgc ccgtgttggg
    98701 gttaaggaaa accatctcga ttttcacatc agatttatcg aattgcttgt ttcgaatcag
    98761 ggtaatgtat tcttcgcgaa cgttagaaac ggttacgtta atcccgttgt tgttgatctc
    98821 cttctcttcg gtattcgatg agatttgaag aaaatcaccc gttgcgagat acgtaaatcc
    98881 gttatagtcc aaatcgaaat acccatctgt aagccgtaga acgtcccctg acgctgttat
    98941 cacttcgata atgtgaaaca tcgatccagt ggagaaaagc tgcggtagcg tcaatctaga
    99001 cacgttctga cctgtctggt cgttgtatac ctcgatgaag tccagattag tgcatagttt
    99061 gctgaatgat tcttgaatag ttgccattat acattctcca ctaattcgaa tttcatcttg
    99121 ccaatctggg cgatcttcca atcgatattt tcagttttga gaacaaattc gccttctacg
    99181 ttttgatact tgatcacctc acccgccagg acgttctgac gcaagttagg gaagagtttc
    99241 atttcgccac ctgatttcac atcttcggtg atcgtgtaga ttttcttgtg gttctcaaac
    99301 tggatgatag ttcccgcttt cagtgttccg gtgaagttgg agattctcac cttacgccca
    99361 ccgcgagcag taccagcagc agccgtaacc atctggcgta catcacctgt atattttgaa
    99421 aagtaagaca gtggcacact aaaaggacga ccaaaaaggt gacgtgctac aaattctttt
    99481 acttcgttaa tatcctgagc catgaaatta gctgtaaatt ctgcttcata aaaatgaata
    99541 ccagtaaagc gacgctggaa cttaccagaa atagattgcg ccttgaagaa aggttgtttt
    99601 gatttaagag taaaatctgt gattttaata tttttggatt tgaacataga aaaagccccc
    99661 atagttttat gattatttat cactatgagg gcttttaatt acatcttacg gcgctgtgcg
    99721 tcttctaccg cctgagcaac taacttagca tgacgtttga tagcatccat gaccatcttg
    99781 tctgagctat taacgttgcc gttaatgttc aaaggtgcgt taacttcaat cggctgagag
    99841 ttaccaccgc ctgatttttg agcagataag aagtctttca aatcaccgtt agtacgctga
    99901 tcaactactc gttcaccctt atcaagcagc catgtaccct cacgagggat gttatcaata
    99961 ccatcatgag ccataccgct aacgttagta gacttgatgt ttgcgatgct ccccatgttc
   100021 tgagaaacag ccaatgcagc agcagcgatc ttttgtcctg tggtgacgtt ggtcggatcg
   100081 ttccatgcat cggtagcagc cgtccacatg ttcaccgtcg cttgtccaat ggagaatgct
   100141 ttatgagcat tgaaagccat ctgcattgct ttagtgtttt cctgcccgaa gagagtcatt
   100201 gcagcagcaa aaccgccgta catatcatcg gctattgact ggcgagcatc agcatatttc
   100261 ttttcaattg cagccatccg tttttgatgg ttttcattga gtttttctaa tgcttccatc
   100321 cgtttagccg gatcggtgat cccatcaatc ttgagtttat cggtcttata atcttgttcc
   100381 gcttccgatt tctctttatc gattgcatta aatttagcaa acgggttatt tgagtcttga
   100441 taatcaaatc cactggttaa ttgattggtt ttaaaaccat ccattccctg taaatgacta
   100501 tcaatctgag aatagttttg ctcggtatca ttcacacgac gcatatattc ttcgtaggag
   100561 atagctttac catcaagtaa ccgtttatgg ctttctaact cgttgtccct gatttgttgc
   100621 aaaactgtta aggcattcaa agcatcaacc ggatcagcac ccagcatcat tttatagatg
   100681 ttttctgcgt tctggtctaa cagttgctga cgtttagcgg ctgcgtcttg ctgtgagatt
   100741 aagcccagat ctaaagcagt gtccaaatct ttcaagctgg cttctaactg cttgttttga
   100801 gaagcaatag acgcggctgt ctgaccgtgc aatctaacat caagagcatt cagcttttta
   100861 attgcatctt cacgctgttt ctgtgctttt tctgcggcct tccttgcttc ttctgccgct
   100921 ttttctgctt cttcttgttc tttttttgtt ggtccagtga cgcctccacc ttgacccgtt
   100981 ggggtaaatc cagtatccga tttatttcca gtgatagtaa ttaccggatc gccgttttta
   101041 tcacgggtaa ctccgtcttt atccacccaa cgatcaggat aatttggttt attgttgaag
   101101 ctggcttgtc cacctgctag accagtagaa ctataaccat gcttgttaat aaaaccaccg
   101161 ttagccatag ccatattctg gcgagctttt tcaaaccgtt cattaaaagt ctttaatgcg
   101221 ttgaataaag cggtcttttc ccaatcttta tcaaaccagt tgtataactt gttcatccct
   101281 tcaacaactg gatttagcgc atttgctgcc atacccttta agttatcggt aagggtatcc
   101341 atatttttag agaatttatt atattcttcg gctgtatcat tggtgatttt aacagtttgc
   101401 tgattaatgg cgtttacagc ttcctgataa gatccgtatt tctgcaattc atcagccata
   101461 tgacttgaat cactggctaa cgattccatc ataaacttaa catcagcgat agacgcacca
   101521 gccttgcgca tatcatagaa gaccttgatt gccgctttca tcccaccttg tggatcgttc
   101581 ataaactcgg cataatcttt aatcttcaaa cctacacttt ctaggtcgtc ttcaataccg
   101641 ccaccgttac gccatgcatc agccagttta tctaaggtgt ctttgttaat atcaccaaat
   101701 ttctcaacgg ttaagccagt gccagagaat tgcttctcta atttctggag tgtttcgacg
   101761 gttaaaccag ttgcttttga aacttcgctg tattccttta cataatcacc gatggcattt
   101821 gcagcagaga cagcaccagc agccagacca acaaaaccac cagcagctaa agcaagcgat
   101881 ccaccagttc cgcgaagggt tccacttaaa ctagataaac caccagacaa atcaagattc
   101941 attgcccttt ctgaaaggtt atcaagcatg tcaatcgctt ggttggtact tctccttaga
   102001 ccgtcattat tcccttctat tgttactata tgtcttgtca taaattaccc ctttaaccgc
   102061 ttctgagttt ctcaagcaaa gatggatcaa acatgttcag cattgccgct ttacgttctt
   102121 cttctttctt gcgtgcaatt tcttccagtt cttctttagt tttaaagagt ttttcttctc
   102181 taattaattg gaattggcta ggcttgagtt tgcgtgcagt ttcgcgtgtc attccttgcg
   102241 aagtcatata catggaatat tgcaacatcg cattctgcat atcatgaaac gcggggcttt
   102301 gtggttctaa gtaggtgtcg aaaatgtata atttccaaaa cagagtgatt gacatattat
   102361 ccatttcatc tttactaagc cccgatctca tcatttgccg gaaatagaaa ttcagaagcg
   102421 ggtttacttt acctcgtttt caattactgc cggttcttgc atcaatgacg cttgagcaac
   102481 taaaccgatt aattcactgc ggacgttagt atacagtgcc ttaacttgtt ccatagattc
   102541 aaataccggt ttaccgtctt catcttcaat acaacgaaga atagaacgtt catcacggtc
   102601 atctttatcg gtattgaaaa catgttcgtt aaattctttt actgacatag ggcgagcata
   102661 gaaagtgaat ccaccgatgg tcagagattc gcgtttcgga gaaagagctt tcagcatttc
   102721 attaatattc attcttgttt cctcttaagt taattcgata tgtttattta gaattggaaa
   102781 caaaaaagcc accccgaagg atggctagat aatattagag tttctggaaa acagcttgtt
   102841 taaccggagc accatctact acaaaggtga aggtacggcc tactacagca tcttcaccgc
   102901 ccgtcatggt agttttagac aggaagccgt tataagcgat gtgcacacca gattttttcg
   102961 tagcgtcgat gtagtaagca attttaatct gtacgcgctt accgtcttcg gttgctttaa
   103021 tcagtttttc gtgtacttcg ttacccggca tgtagttgat cgaaagttcg atatccggta
   103081 cagacatacg accaaccagc ttacggttat acggaccacc gaagttagga acatcgacag
   103141 tagaacgttc tacaccagtt tccgggaaag ccgcacattc tggaatttcc agatagcttt
   103201 cactgtcaag atcggtgtta gttacttctt catgcagaaa cagaccaacg aggccaccag
   103261 aaaaaatatc aaatttagta gtcattattc ttttccttct attttaaaca atagggtaca
   103321 tacccgtaat tctatttatt aacggttact caacctacga taacgaagat gagcaatccc
   103381 tctatttgtg ctaacggtaa ttaccgcccc ttgcggtgca atacaagaat gaatctgtcc
   103441 ccaatcatga cccttatggc ttccagaaac acacaaacca tgaataagca attcagagtc
   103501 accaccgcca ccaccggaag aatgagcaca gaatgaaata gtcccgaaag cgtcggctgt
   103561 ccaaccgtta ggaatatcaa accatccttg atttgcttta cccgccctat tccccaaagc
   103621 gccatctacc caaaatgcca ttagtgcatt ctcctgaatt taaaataatg caaactacct
   103681 ttacccaatg taaagctaac ggtagcacca gcgccaacta aagaactagc gccccaactc
   103741 ccagcatcac cagcatgatg acctgattca atcaatccat ttacagccaa ttcagaatca
   103801 agatcaccag caccgttaat ggcttccata tgagcaaaaa caattccgca tgaatcagta
   103861 acccagccgt tggggatatc aaaatatcca ccattagccc aaatactaat agcgtttgac
   103921 attctttgat ttatccatcc agccataatt aaaactccat gaatttaaaa tattcaacac
   103981 caccttcacc ccctaaacca aaggagacgg tgcagccagc aggaacaaac gaatttatag
   104041 tagatcccca attggtccca ccacgacgac gagcaacggt caaaccatct acgttaatat
   104101 gtgcatcaga ccacccacca ccagcattat gacgcattac agcgacacca gcacgagcag
   104161 taccatagcc gttaggaata tcaaatacat gccattttaa agcatcgatt ttagtattaa
   104221 tttcactact tacccaatat cccatataag aatccttagc ggagatttct ccccgctttc
   104281 caattaccct aatttagctt caattgcagc aagacgttca cgaagaagtt tattttcttc
   104341 gctcatttct tggaccgctt taattaaaag cgcgttcact gcggagtttg aaattgttaa
   104401 aatttcttct gggttatcaa aaccaccaat gtttgcggtt ttaacagctt ccggtaatac
   104461 ctcttgtaaa tcctgtgcga taataccaat ctcatgacct ataacttctc ggtcattaag
   104521 agatttaact ttatcgtagg ttttaacttt gagtttattt accttatcca ccgcattttc
   104581 ttcgtaatct tcaacattaa ttttcagacg acgatcggaa cgaatataaa catcgttaaa
   104641 gttaccatta ccaggacagt aaaaagtacc atcatgatgg aactcgaata cagcttgagg
   104701 atgaccaggc gctggcgatg cctccgcaga tccaacacga ataatagctt gcccccaatt
   104761 ttgaggaaca cgacgcatac caaaatcgac ggcagttgta tacccttgat tggtgattaa
   104821 acttcttcct ttaataattg ggtaataaca gtccggtgaa acataaccat gatcgacaaa
   104881 tatcggcgct tctaatcccc attgatcgcc ccaacctcca gattggctag cagtccaacg
   104941 ttcaccatga acatagaatc gaacgttatt gacatgagtc atttcgacac cttttggact
   105001 tagcgcgata tcacccgcgt ttgtaatatt gatagcagca ttagtagcat agctatagaa
   105061 cgctaatcca ttatcagcac cacctttacc gatataccag ttgttattat cagcacaagt
   105121 acccaacaaa tatatagacg aatcgccact ttcggcattc atgatgattg cgtcagatcc
   105181 acgattaact ttaagtttcc cgaagaaggt gtttttaatg gtattatcac ccaatcgttc
   105241 aaattctgcg aaaaatcctt ttgagtcacg aagacttaaa acgttatttc gacctgtatt
   105301 gcttgcaccc caatggacga gttccatata gtccatagat tgacgagaac cagctttaaa
   105361 gaacaggttg tcttcgagac gagtgctacc atcaattccg agatgcaaac aacgagcggt
   105421 tgcagtacca cctaaataca atccaccgtc cgcaaaatca tagctgaatg gtctgcgatt
   105481 attccaacta ccaaaagaat cttttaaatc ggtagtaaga atatggaagc tagaaccatc
   105541 attgcgtaaa atcaaaccat agttaccacc tttgacagcc aaacgagcat tttcagataa
   105601 tgcaacttcg ctattcatta caattttctg gcctttaccg ccagtaatat gcaattcacc
   105661 atcttcaatc aggtttatag agttttgacc gttatcgttc caccaaataa aatctttggt
   105721 tgttccatca ccaaaaccaa accaaccatt acgaacatct tgtccagtgc gataatccat
   105781 gaaattaaaa tgacttgatt cgtttggtcc tcgacgaata tcaataccag aatttccagt
   105841 aacaccgcca tccaatgtta atttcttgac atgtaacccg gatgttgctg tcagcaataa
   105901 ttcctgattt gtatcttcgt atccagtagc aagacgatat gcgttatcat caactgtctc
   105961 atgccagatt gtagctggtg cacaactacg gaagcgacgc aacatctttt tagcatttgt
   106021 cggttgttcg tttaaatgct caatatcata ttggccttga tggtttccgc caaaatttaa
   106081 cgttccacgg ttgctaaagt tattgaacga tgaaatgtta agagcatcaa aaatttcatc
   106141 tgcaacaggt ttttcaccgc ccaggtattc aggagtatcc aacaggttta aagaaacacc
   106201 accggaagaa acttgatatt ctgctaaaac aaatcctgta tgtgcaccat agtaagcgta
   106261 aagatcgtaa ttatcaccat cggtaggaat tgcacaaaaa tgttgttcgt gataccagat
   106321 gctataataa gcattgaata caacaccttt cgggctattg ttgccgcatc gaatcaccaa
   106381 ttcgataata ttggcttgtc cattcatccc gacgttataa ccgttaccac caaccaaacg
   106441 gatcttagcg gtgcgaccgt gttgctgtgg cattgtcaaa gtgcctagtt taaaccaacc
   106501 gccctcgata ccaaaattaa gcgtcttctg gaacaggcgg tcaatttctg ctttcgaata
   106561 tgcgccaatt tcagccggag taggtttatc accttcatga tacatgcggt gagaatatgc
   106621 caaatgaccc aattcatcat agccgtatgt tcttaccgta gcatgtggat tagacccata
   106681 agtgaactca aaaccacgag catgattaac gccggatgga tgcggaacat gtaacgctaa
   106741 agcaatatga cccgctaggt cattcatacg gaatgcacca aagtaatcaa gattacgcgc
   106801 acttggatca tcaaaatagt ttgcggtctt agacagcaaa tagccatcag tgtaagtgtt
   106861 tacgtgcttt ttgatgtact tgccatcagc agatccatcg gctgcatcaa tacggctttc
   106921 taaacgtgca agttcagaat cagtgtaaga cttgttattg tcaactttgc tatgaattgc
   106981 tgaatttttg gcttcaacat cacgggttaa tgctgcgacg ttatccgctg cctcttgctt
   107041 attggctgca atcacaccag taaggttatt gtaggtgtca gttaactgat tttccgcata
   107101 ggcttgattt gctgcgatag tgcggtcagt ttctgcctta atcaaatcaa ctttgtcatt
   107161 gattgctttg tgattgcttg cgatggttgc atcggtacgg gatttaatat catcaacttt
   107221 tttattgatg cgggtgtcca gttcctgagt tgctacagca gccgcatttt tattagcgtt
   107281 gatggtatcc gacaattcag ctttaacacc agcaagatcg gaagcagctt tatttttatt
   107341 ggcctcgatt gtcgcgtcgg tttcgcgttt aattacatca actttattgt taatttctgc
   107401 gtgatttgct gcgatggttg catcagtagt ttgtttaatt tcatctactt tagcgtgaat
   107461 attgcggtca tttactgcaa ttgtgctatc tagttcttgt ttgttagcat caactttaga
   107521 ttctagtgcc gcgtgagttt caggagaaac agagatttga actacttcat gatctcggtc
   107581 tttggtaaaa ataacatggt ctttaaggtt gattgctacc tcaccgacct gtaattgttc
   107641 cggcgttggc tttttgccag ctacattagt tcgcttaaat tggattgatt gcatctaatc
   107701 acctcacata aaacaggaat aagggaggcg ttaacctccc cgcgtcatgt tttatttaga
   107761 gaagcaatca gtattccccg aagtcgatcc tgtcatggat agaaacggct tcaatctcgg
   107821 ctggtgtcgg tttttcttct gtggaataca ctttcaccca tccagaatta ccatctttct
   107881 ggactgtgcg aactcgtaaa cgtggtgcgc cggaagcggt gcaagttaat tgccatccac
   107941 catcttcatt aggttgaacg tgaattagtg aagtatcagc actaaatggg ttagatgcgc
   108001 tcgatccctg ataggttacg aaacggtttc cggctaatgc ctcgctatca atcggaccag
   108061 tgaatgggct aacgcctgag cctacgccat aatccccttg tcgcagaatt tttccctcgg
   108121 tcgctatacc ccttgcgagg attccgccat ctggttcaag tttaaattcc agtgttacag
   108181 ctttgttatc gctaccacgg gttttgtgtg atgtgacgta agcatcatag atgacatagt
   108241 aaccagtgtt agcagcacta tagccagagt tcacaacata gaacatacgg aagcgtaaag
   108301 gtgttttatc ctctaccgct ttcatcaaca ttgcttgatg ttcatcgtca agaacacggt
   108361 ttaatgtgag tgttgtcggt tccagtttac gatagccagc aagtttaccc gtagcgtcct
   108421 gatcatactc ttctaacgtc tggatctctg tggattcggt tatcgtcggg aatgctgcga
   108481 tgttctcgat aggactaaat gcaggatcga aaaagtccgg ctggttatcc accatagtag
   108541 acacggagac ttcaacatgc gaccccgtga aaatgtctaa gttatcttgt gtaatattca
   108601 ttattacccc ttaaaaacgc gctagataag aaaatttaag gctaagtgtc ccaacgatac
   108661 ccccatcact agaatcatcg tcataatcgg tattagaggc tactggagtg atatctgaaa
   108721 tagagaagcc caaatcttta aaacgtgggt tatccggctg aatctggatt atctggcaaa
   108781 taccctcatg aattttcgtt tcatgaatct gagaatataa ttgcatttcg ataacgcatt
   108841 cagcttgcat tgcattacca ccacggaccc tagtgtaagt ttcattcatg ccagtaatcc
   108901 aacaaaccac gtcatcacta aagccttgct gagtttgttc tacgtttaaa gccagaccta
   108961 aatcttgttc gataatatct tgcaaggcgc gtttgatttt cagtctaggc atattattaa
   109021 cggtagcgag catgtgtacc ccctgccaga gtaataaagc aatcacaagt attatcacca
   109081 ttgcgcttaa cgtattgaac tttgaaacgc tggttttcta caatgacaat atcaccttgc
   109141 tttaagtctc cctcacgaca gaatagaaat tctgtttctg tcattacccc tgattcgtcg
   109201 gtagtagtaa tttcatgata agcacgaatt gatttaccac cttccaccga aaatacagga
   109261 gcacttcgga acattcttga taattgtgat tctgataatt tgaacatagt tacccccttt
   109321 atggagtatt tacatacaaa aaagccccac cgttaggcag ggctaattat tattctttag
   109381 ttttacgttg ttttttaact gtggctttcg ccgtaacctc ttgaacttct tcttcctgag
   109441 atggaatcag attttcttcc cccaaatcgg gggaaggttc agaaggttct acgctagttc
   109501 attcagcgga gatgtgaaga actttcagag cttccggctg aactacggtg aagtccaggt
   109561 ctacccagat acgcggaacg atagcagact gtgcgcggta agtggtgtcg tccatatcca
   109621 gttccagacc accccattca ccgatcatga taccggagaa atcacccaga acgatgtggt
   109681 ctgccggaat aacgccagaa gtaactacat cgtaaccagc cagtttgccg ttttcgatga
   109741 tataaccgga aacgccgtta tctttcaggg tagattccag ttcagcagca gttgcaccgc
   109801 tcatcgcaaa cttgatcgcc tgagcaggaa cgccagcgtc ggtcagtgct gcaatttctt
   109861 tcaggaagtc tttgtaagag aaagccgctt tcttagcaac gcgaccacca tctaccagtt
   109921 gtttaaccag acctttcgga ccgcgagtat tatctttgtc agacagaatc agttgttcca
   109981 gtttgatgcg aacagctttg ttaatatgat cagtgatcag ggtagcaata ttcggaacag
   110041 ttttcagaga ctgacggctg atcgggttgc caccagcaaa agttttcgga gccattttca
   110101 cgtttgcaaa ttcagctttg ctttccggtg cagcaccgtt ttcatcaacg aaaccgaaag
   110161 catcaacgct ggaagtagtc attttcggta cagcaatcgg agcattcaga ccagacagaa
   110221 cagtcacacc gaggcggcct aaaacactct gaggcaacag catttcaaca taggattcgg
   110281 tcagcagttt ttcgtcggtg atatcagtca gagtagcttt ggtgttacct tcggaagcag
   110341 cacgcagagc agcagccgga acgaatacgg agccaccacg agcagcacga ccacgctgca
   110401 ttgcagcacc agcagccata gcggaatatt cagcttcgtt agcacccaga gcagcaccat
   110461 ctaccagaga gcgaattacg ttgttcaggt caaaagtttt ttccatttta gagtccttaa
   110521 tttgttcgtt attacgttga gcattggtaa tgttatttag tgccttagtg cggaatgctt
   110581 ccggcgtaat ttctttattt gccaatgcgc gttgaaattc ttcgtcgtct tcgttaatat
   110641 ttaactcgcg tgcaatttcg cgaatttcta attcgtcttc ttcggaacgt tcagccactt
   110701 cctcggtttt ttcttcttca accggagcag cttcacgttc ttcttttact tcttctgttt
   110761 cccgaacagt tgaactatca tcatcaacac tttcaggatg tttagcgtct tttccgtctt
   110821 cgagattttc atcttcttta ttctcttcaa cttggcgctc ttgagttttt tcaacttccg
   110881 gttctttatt ttcttctacc ggagtttctt caacctgagc gggttcttcg tttttgattt
   110941 cttcgatttg ttctttagtc atatcgcgtt tagcctccaa attaactgtg atagtattta
   111001 gagagcgatt taaaccgacc gtatcatcgg cagggaccgt cacaaatgaa atttcaaaag
   111061 gttcccactt agtaacaatc aattgtcctt tggcgtaatc gatgcgatat tctttaatgt
   111121 catagccgac agaaattttt tccatcgtac cttcaatgac tttattacga atatcattag
   111181 acaaagtgcc atgcttggag aatttaacca gagcacggcc tacgttatcc gcatcgattc
   111241 gagcgttaca aacgacacca atgtgattat cgaaaatatg attgaacagc aacggagcgt
   111301 tattattcag acgagacaga tcaaccgctt ccggtgtatg taccagaatt tcatctaata
   111361 ccaccatttc ttgattttgc tcatcccaga atcggcgctg ataaggctgt tcactggaga
   111421 aagcaatttc aaattcgtat tgatcattct gcccttcgtt aataactcca ccgtaaccgt
   111481 taagatcgcg gcgaaattta agcatttaac cacctttaat taattggggg cattgcgccc
   111541 ccgttagtta ttagggatcg gctggggaat ttttttcttc accctcgcca ttaacgataa
   111601 tatttagtgc gctcttttcg gcttgaatct ctgagaatac tttttcagga tcatcaccac
   111661 gttctaatat aacggcagta cgtgatttaa gtccgttatc aattaaagca atctcggcgc
   111721 ttacgtcttt aaatggatcg acggattcaa aacgcggacg aataatagta gtgttatcga
   111781 taatatgtgg aattgcagta atacgaatcg gaacaacacc acgcgcggaa taatgacgca
   111841 gatacgcttc gaaaattgct aacaccactg tttcaatcaa tttgttttgc agtgctttaa
   111901 tgcggttacg ctgagttaat tcaccaaaac gtgcggctga gtagttgatc tgtgaacaat
   111961 ctcctgttaa gccctgtttg aacacgccta agcccattga tacgctagta aacatcgcat
   112021 cattgaagct gttaaaatca tcgcctgatt gagtagcttg gattgattta atcgttgccc
   112081 cttccggcaa ttcctgaata gtacccggtg caaagtcctg tactacttcc ggcgcttgat
   112141 attgttcatc ctcttcacca gtatcaaaat cgtcaccaga atctttcgga cgttcgataa
   112201 agcccataga actagccgca atacgtttct ggacgatcgc agtttcgcgg aatgcgtctt
   112261 gatgtgcgat atccttaatc actggtagga agtcagtcac accacgcagg gattcggctg
   112321 taagtggttg atagtaatgg catacttgcg aagcctcgac acgatagtta tcaccagtgt
   112381 aggtttgagt cagtaggttg actttacgaa accagtatgc tacgggcttc atcgtctcta
   112441 cgtcatactc aataccctga tagatcgcac gctctttgct tacttcacgg tttagcgacc
   112501 agtcgcactt atcagcagac aggatagaaa catttaactc attgttttct ttggttaaaa
   112561 cgatgaagca ttcaccaccc ataacgcgct cacgttcagc catcaccagc agttcacgga
   112621 agttaaagcg accgttacga gagaagcgtt tagcattttg cgcccacttc cagaaagcat
   112681 tctcgatctg cttattcagt gcgctatcaa gtttgccatt tgatttaacg attgatggct
   112741 tcggatctag gccagtacct accaccatat cggtgatgta ttgcgtgtag cgactgccta
   112801 cggaagtgtt taaggccaga gtacgaccct gatcataaag gcgcttacca ttcgatttga
   112861 gagccttatt gaaggttcct gtgatagtat cttgttgaag cgatccatca atgcgatcac
   112921 caactaagcc caaagaacgc ttagacaaat ctttctggaa tttttctact tgtttgtcga
   112981 taaagatttt ttgttgttgc tggcggtgat tagttttaac tggagtttct accgcctttt
   113041 tgcgtcgaaa aagattaaac atgatttacc ccttatcgcg taagacgtac tttaatattt
   113101 ttaatcgggc taattccctg tttacgtcgt tcggcttgaa ttaattttga taactgacgt
   113161 tcataatcga cttttagagt ctggagaaca gccaatgact cataggcgaa agtattccct
   113221 ttcactgtca tttgagataa tgcggcttcg tccccagata aacgggcgaa aataacttgc
   113281 tcgattgtgg cgatagtttc ccgcagatat tcttttttgg attgtttggc gaataccggc
   113341 aatacagtta attcctgcat tgataccagt tcatcttcca acgtggttac gatggtatat
   113401 ttaccctcgg caaaatctaa ggttttaatc tcgtgattag ccggagtatc atcaacctga
   113461 taaatgatac ctttactatt tcctacctga attgttacac cctcttcatt cgccagcgtg
   113521 attttttcgc ctttacgaat tactaaggga attagttcta aactcataat taccccttat
   113581 ttaattgtta ttggattaac aatatttagg agcaagccgc cccgaaggac ggcgagttat
   113641 tagaacgatg ttacccagct acggccttta tttgggcgtc tggcgatgtt ttgacgttgc
   113701 ggtcgtgtga ttggcttagt ttcttcgatt tgctcgttag attgcgattt aggagctttt
   113761 acgggttctt cgacaacacg gtttaagctg tctttcattg caatgagttt atcccatgac
   113821 atttttgaaa ggacgtagcg agaagcagca tagctataaa ccagacagtc gagagcctcg
   113881 tttcgggtac tacctggatt tttcacccaa cgcacgccag tagtagtacg cttgatggat
   113941 tcactcaaaa gctgatcgag ataatcatca ggaacggttt ctgatatttc taagccaata
   114001 tgaggattat ctttcaggtt tctaaccagc atttcacgaa cagcggattt cccaacgtta
   114061 acacccaaca taagcaattc atgaccacct gtgcgggtag gtttaaccgg aattactgga
   114121 gcattaccag atgaactacc cttgatagcg tgtaggttct tccacttgcc gcaaatacgg
   114181 tatccggctt gagtgaatcg accgttcgat gtatcaagga agctggcgag cattggcaca
   114241 cgttcaccat taacgttata gaatttggtt ttcttgaagt taaccagacg atcccaaaca
   114301 ggtgattcat atcgttcaca gttatgatcg taaaagctgc ggtgatccag aatgtaaacc
   114361 ttatctttcg ctacacctaa gatggtagac tctgcgcggt ctaattgctg gtcaattcct
   114421 gagcacaaga aaatcacgtc atcagggata ttctcgatag aaacatctgt tttgagttgt
   114481 tccagttcat ttgcttctac tgccgtgtcc tgatcgtcgt ataccttgcc taatacggtg
   114541 ttataaaatg attgtaaatc aaaggattgc cacgcatgac taaaatcaac cacacaagcg
   114601 cggatcgtgc tgaaaggtga atacagacga ctgatccaga atccggctac ttcactttca
   114661 cgggttgctc tccactcgcc ttgtgctact gccctgattc gttccccttc ggtccatgcg
   114721 ttcttacagt gggggcaaat ataacgagcg gtatcaggat cgggtaagtt cttaccatcg
   114781 atgttacgcc attcaaactg tacgttttcc cactcgatca cctggtgttc cccgcaatga
   114841 ggacacggaa caaaaaacat acgcatatcg cttgataacc attgctggtt aatgcttccc
   114901 agcttactgg tcggggtact ggatacgact aatcgacctt catcgccaaa ggtagttaaa
   114961 cggttagcag ccagtgccac cggatcacct tcttctgagg ctgtggcagc atcgatttcg
   115021 tcaagcaatc caacctttgc ggtcttaccg cgtagggttg atggactggt aagcgatacc
   115081 atgtacagga agtgattcgt ttttaactgg agttggttat tgttgttaac cgcattacga
   115141 tcattcttgt ctgtaaccac gtctttcaat gcatcacatg cttcgataga cggtcggatc
   115201 ttacccgcga gatattgcga catttcttta gcggttgatt gtccgataat catattgcat
   115261 ggatcgttag ccatctggtt aaacaggata ccgtttagga tggtagtttt tccgatctgc
   115321 gcactggtca tcagaacata ctttttctta ttctcaagga aaggagcatc aatcatgcct
   115381 ttctggaatg acagcaattt aactttatcc cccgcttgag gaccatctac cagcaccata
   115441 ttcgcttcgc accattcaga aggaaggagt ttaggcggtg gcgtaatata ttttgcggca
   115501 tttttaagaa tcttttttaa tttggccttg ttcgaaatca gtttcatgta attaccctca
   115561 ttacgaaata tgaaggtatt tattaaattg ttgatatttt gataaatatg gtattaagat
   115621 ttaagggggt tgtatgctaa ttaatcagca agaaagagat gaattagaat tagccttgtc
   115681 ttgtaccgat catgaatatc gtttgccagt caagcataag catttaaaga ctgactacac
   115741 aacatccggc tttagtcgcg aggaagcgaa agagatttta atagagtttt accgcgataa
   115801 tggttataga gacgttcgca acttctttag caagcatcgc acatcacata cagagtttcg
   115861 gagagtccga gattggtttg attttgacat taagcggttt tacagaatcg acgatggtcc
   115921 gatctatcgg ttgcaatgga agccactaag ggaagtgttt aagcatgaaa ggctaaatca
   115981 cgctgttaca cgctatcgta acgaggcttt caagaaaggg tatggtgata caagggaatt
   116041 gttcgttgaa ctcgctaacg tgcgatatag ccattattac aacgatccta aagggttctt
   116101 tgaagtgctt cgcaaggtgg atattagtcg aggtacatac tattcacggt tgaggcagta
   116161 cgggattaag gcagagttct ttatgtcggt tgacgatgga gaactttttc ctataaaatg
   116221 taagtcctct aaataaaggt gaacattcac tttaatttgg agaaaatgac tatgactact
   116281 aaagctactc gcggtcgtcc ttgccgtttt gatcgtgaac aactggcagc gattgtaaaa
   116341 gcgtactatc aagcgccgaa aggtaaagcc gaaaaagaac aagtattgag tgaacacggt
   116401 atttcaatcg ctcaattcta caaatcactc cataaagttg atttgaaatt cttcgttcag
   116461 gttgacggtg aaatggtaga agcaacagga atttgattct ctaggccaat ccttcggggt
   116521 tggctttttt atatccgctc aaaactgagc acatctctaa gtcattgatt cttccgatga
   116581 gtccagattt ggactgatct atagatgccc tcaaaactga ggggatgtgc ttaaagttca
   116641 gcgtatctat ctaagtggtt gattctttcg agaaattcaa acttgaatca atcggcgcaa
   116701 aactgcgctc atctctaacc tattgattct tccgataaat ccaaatctgg atgcatcaga
   116761 tacaaaaaag cccagcgcaa ttatgcgccg ggcgattaat cagatcccaa aatcaacaag
   116821 ggaaattacg ttacctgatt cacgaatctg tttagcagct ttgttttgaa tcagaatagt
   116881 gttatttggc tgcggtagtt taagagttgc tttctgttct tcttccaaaa cgcccaattc
   116941 aaccagcacc ggaagaacat caacagtaaa ctcaagttgg tagtgagcat tcatgcggca
   117001 gaaagacaga gaagagtcat tagcaacata cccacacggc ttgttatttt catcatagac
   117061 gcgctcaatg tatccagcag tacgtaaggc cgtcagtgct tctttaacct tcgtagcgcc
   117121 ctttttagcg cctaacagac gtgtcataga atggctatct acggatttgc gaatgtgtag
   117181 ctcaatcagt tttttatttt tgcgtttttc atctaatgcc agttcgatcc aatcggtttc
   117241 ttcaaagtct gcatacgggt taacaggagt attattggcg gttttcagtt tctcttccag
   117301 ataattccaa cggtcaacca gttggcgagt aaattccggt acgttttgag caatcaagac
   117361 aatcgaatct aagcgacctt gctcaccctc aaacacataa tctttaacag taacagcaaa
   117421 ccctaagtta ttgattttct cgaaattctt cgttgcaggt tttcggataa cttggcgttc
   117481 aaccagtcgg ttcatagaag tttcaaggtt tgaaaaacga actccaataa ggtcggcaat
   117541 ttcacgaaga gtcatttttg caacttcgtt atcaacaacc agagacacgg aagcagtttt
   117601 aacagcagta ttcatagtag taacagtatt catagtagta attcccctta aacggttttg
   117661 cgataatgat attgatcctc ctagttccgg cagcatcacc ggaacaattt tatttataag
   117721 aagtttttat ctcatttaga ttcagcaatc gcgcgatcaa tttcttcttg aatgcgacgc
   117781 tggcgttcat ggaagtcaac cattgagaaa ttcaggtttg gggtccacgg tttgcggttc
   117841 gggtttttac gtccatcaat tttcttagta gtgttcataa ttaacatccc ctttacaaat
   117901 ctaggtcaaa taggttcaaa gttgtcaagt gcgataatca taaaaaagta ataaaatttt
   117961 gtcaataccc cttgacaaga cgccaaaggg ttgacctaac ttacagcata tctaagcctt
   118021 catcgtaacc gtagaagcca ttctgagaag agaaacagat tggtgcgtag tcgtcgtcat
   118081 cttcgtcttg ttcatcttct tctggggctt cctgagcggt ttctttgccg tagttaaaca
   118141 ttgcttcatc cagatcacag acagagaaga aactacctaa atcaatgtca taatcacgga
   118201 cttcgaaagg aaggtattcg ctaacgatga tcgctggaat gttctggtat ttctcacggt
   118261 cttcatcggt taagcagtta actacaatgg tcggcttctt gttacgatgg aaggcatacc
   118321 atgcactaga gaaatgagat tcatcggtat tgaaaaggat attgtatcca cgttcacgga
   118381 acatcttcat taacttgtca ttgtgaaagc tatctgcatc cagacccaga agaatgaaag
   118441 gagtagtggt agtcatcttg tggttcatag tggaaatcct ctaaaagaaa gtgaatcaaa
   118501 caaattacac tagtatttat aacgagaatt ttttatctat ttggaaggga ttggtattca
   118561 gtcgggcata gccctccttc atagattttg attaaatcat catcaaaacg aagaagtatc
   118621 tttagaatat aagaatcttt cttttgaaga aataataata atcaggaagc aatttcagca
   118681 accgcaggtt gcgatcccga agggataa
//
LOCUS       DAZUDJ010000007       117582 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.007, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000007 DAZUDJ010000000
VERSION     DAZUDJ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 117582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 117582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..117582
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.007"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..209)
                     /locus_tag="ACHY1N_000734"
     CDS             complement(<1..209)
                     /locus_tag="ACHY1N_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFS4043079.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVE"
     gene            complement(280..2394)
                     /gene="fusA"
                     /locus_tag="ACHY1N_000735"
     CDS             complement(280..2394)
                     /gene="fusA"
                     /locus_tag="ACHY1N_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFS4043080.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
                     RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEW
                     HQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPL
                     AGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDEAPSNVAQAVIEARGK"
     gene            complement(2491..2961)
                     /gene="rpsG"
                     /locus_tag="ACHY1N_000736"
     CDS             complement(2491..2961)
                     /gene="rpsG"
                     /locus_tag="ACHY1N_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFS4043081.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(3058..3432)
                     /gene="rpsL"
                     /locus_tag="ACHY1N_000737"
     CDS             complement(3058..3432)
                     /gene="rpsL"
                     /locus_tag="ACHY1N_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFS4043082.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3558..3845)
                     /gene="tusB"
                     /locus_tag="ACHY1N_000738"
     CDS             complement(3558..3845)
                     /gene="tusB"
                     /locus_tag="ACHY1N_000738"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002143 - tRNA wobble position uridine
                     thiolation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HFS4043083.1"
                     /translation="MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYL
                     ESLRNAPIKVYALNEDLIARGLTGQISNDIIPIDYTDFVRLTVKHSSQMAW"
     gene            complement(3853..4212)
                     /gene="tusC"
                     /locus_tag="ACHY1N_000739"
     CDS             complement(3853..4212)
                     /gene="tusC"
                     /locus_tag="ACHY1N_000739"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HFS4043084.1"
                     /translation="MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGV
                     FQLLSGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLE
                     ADALRRELANYDVILRF"
     gene            complement(4212..4598)
                     /gene="tusD"
                     /locus_tag="ACHY1N_000740"
     CDS             complement(4212..4598)
                     /gene="tusD"
                     /locus_tag="ACHY1N_000740"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HFS4043085.1"
                     /translation="MRFAIVVTGPAYGTQQASSAFQFAQALIVEGHELSSVFFYREGV
                     YNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGIVDETEAGRLGLASSN
                     LQPGFTLSGLGALAEASLTYDRVVQF"
     gene            complement(4598..5320)
                     /gene="yheO"
                     /locus_tag="ACHY1N_000741"
     CDS             complement(4598..5320)
                     /gene="yheO"
                     /locus_tag="ACHY1N_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4043086.1"
                     /translation="MSRSLLTNETSELDLLDQRPFDQTDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMSTFVPPETPDVGSSVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFQGQDK"
     gene            complement(5487..6299)
                     /gene="fkpA"
                     /locus_tag="ACHY1N_000742"
     CDS             complement(5487..6299)
                     /gene="fkpA"
                     /locus_tag="ACHY1N_000742"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFS4043087.1"
                     /translation="MKSLFKVTLLATTMAVALHAPITFAAEAAKPATTADSKAAFKND
                     DQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLV
                     IPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK"
     gene            6520..6738
                     /gene="slyX"
                     /locus_tag="ACHY1N_000743"
     CDS             6520..6738
                     /gene="slyX"
                     /locus_tag="ACHY1N_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HFS4043088.1"
                     /translation="MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(6787..7377)
                     /gene="slyD"
                     /locus_tag="ACHY1N_000744"
     CDS             complement(6787..7377)
                     /gene="slyD"
                     /locus_tag="ACHY1N_000744"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4043089.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH"
     gene            complement(7472..7672)
                     /gene="yheV"
                     /locus_tag="ACHY1N_000745"
     CDS             complement(7472..7672)
                     /gene="yheV"
                     /locus_tag="ACHY1N_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative zinc ribbon protein"
                     /protein_id="HFS4043090.1"
                     /translation="MAIRKRFIAGAKCPACQAQDSMAMWRENNIDIVECVKCGHQMRE
                     ADKEARDHVRKDEQVIGIFHPD"
     gene            complement(7682..9487)
                     /gene="kefB"
                     /locus_tag="ACHY1N_000746"
     CDS             complement(7682..9487)
                     /gene="kefB"
                     /locus_tag="ACHY1N_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015503 - glutathione-regulated potassium
                     exporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
                     /protein_id="HFS4043091.1"
                     /translation="MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGP
                     WGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALL
                     AGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV
                     IPALALVPLLAGSADEHFDWMKIGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFT
                     AATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFI
                     SVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGG
                     EFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDE
                     KPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGD
                     ATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELL
                     QAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADT
                     VQISRAREARRELEEIFQREMQQERRQLDGWDEFE"
     gene            complement(9487..10038)
                     /gene="kefG"
                     /locus_tag="ACHY1N_000747"
     CDS             complement(9487..10038)
                     /gene="kefG"
                     /locus_tag="ACHY1N_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312229.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HFS4043092.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHY
                     PDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSA
                     QELASHARAYGDWLANPLSPGGR"
     gene            10169..12082
                     /gene="yheS"
                     /locus_tag="ACHY1N_000748"
     CDS             10169..12082
                     /gene="yheS"
                     /locus_tag="ACHY1N_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4043093.1"
                     /translation="MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADGGSYTFPGSWQLAWVNQETPALPQAALEYVIDGDREYRQLEAQLHDAN
                     ERNDGHAIATIHGKLDAIDAWSIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIH
                     IEQQSMFEYTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDRIILDSIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADE
                     SPIQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPN
                     LLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVHDRKVEPF
                     DGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIAR
                     LEKEMEKLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQ
                     EQLEQMLLEGQSN"
     gene            12082..13104
                     /gene="yheT"
                     /locus_tag="ACHY1N_000749"
     CDS             12082..13104
                     /gene="yheT"
                     /locus_tag="ACHY1N_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFS4043094.1"
                     /translation="MAQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRQVKFT
                     PYWQRLELPDGDFVDLAWSEDPAQAKHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGW
                     LGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
                     CLLAKEGNDLPVDAAVIVSAPFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAY
                     PGTLPINLAQLKSVRRIREFDDLITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIH
                     AKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTY
                     LEAKSC"
     gene            13098..13316
                     /gene="yheU"
                     /locus_tag="ACHY1N_000750"
     CDS             13098..13316
                     /gene="yheU"
                     /locus_tag="ACHY1N_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HFS4043095.1"
                     /translation="MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKR
                     QLQCGEAVLVWSELHETVNIMPRSQFRE"
     gene            13370..14239
                     /gene="prkB"
                     /locus_tag="ACHY1N_000751"
     CDS             13370..14239
                     /gene="prkB"
                     /locus_tag="ACHY1N_000751"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008974 - phosphoribulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HFS4043096.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYD
                     EAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(14294..14698)
                     /gene="yhfA"
                     /locus_tag="ACHY1N_000752"
     CDS             complement(14294..14698)
                     /gene="yhfA"
                     /locus_tag="ACHY1N_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HFS4043097.1"
                     /translation="MQARVKWVEGLIFLGESASGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPRLFTHINLHFIVTGRDLKDAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVVAA"
     gene            15000..15632
                     /gene="crp"
                     /locus_tag="ACHY1N_000753"
     CDS             15000..15632
                     /gene="crp"
                     /locus_tag="ACHY1N_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HFS4043098.1"
                     /translation="MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            15683..17773
                     /gene="yhfK"
                     /locus_tag="ACHY1N_000754"
     CDS             15683..17773
                     /gene="yhfK"
                     /locus_tag="ACHY1N_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312236.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccS/YhfK family putative transporter"
                     /protein_id="HFS4043099.1"
                     /translation="MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVP
                     ACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLLLAKDVPLPFLLTGLTLVLGVTA
                     ELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
                     LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLS
                     AQNNTDYKRMLRIFQEALDLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARL
                     RVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWHFSRIARVLRTQKPL
                     YARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWI
                     LMTVLLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASY
                     LILRKNYGWATVGFTITAVYTLQLLWLNGEQYILPRLIDTIIGCLIAFGGTVWLWPQW
                     QSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLNQAMQEP
                     AFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQ
                     RLEYDEPGSSGDANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPH
                     HGIWLSRKLRDSKA"
     gene            complement(17840..19060)
                     /gene="argD"
                     /locus_tag="ACHY1N_000755"
                     /gene_synonym="dapC"
     CDS             complement(17840..19060)
                     /gene="argD"
                     /locus_tag="ACHY1N_000755"
                     /gene_synonym="dapC"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     acetylornithine/succinyldiaminopimelate transaminase"
                     /protein_id="HFS4043100.1"
                     /translation="MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEY
                     VDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERV
                     VFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQ
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAF
                     HPGSHGSTYGGNPLSCAVAGAAFDIINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSD
                     IRGMGLLIGAELKPQFKGRARDFLYAGAGAGVMVLNAGPDVMRFAPSLVVEDADIDEG
                     MQRFAHAVAKVVGA"
     gene            complement(19146..19709)
                     /gene="pabA"
                     /locus_tag="ACHY1N_000756"
     CDS             complement(19146..19709)
                     /gene="pabA"
                     /locus_tag="ACHY1N_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HFS4043101.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKP
                     QKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVMHG
                     KTSPITHNGEGVFRGLANPLTVTRYHSLVVEPDSLPACFDVTAWSETREIMGIRHRQW
                     DLEGVQFHPESILSEQGHQLLANFLHR"
     gene            complement(19741..20343)
                     /gene="fic"
                     /locus_tag="ACHY1N_000757"
     CDS             complement(19741..20343)
                     /gene="fic"
                     /locus_tag="ACHY1N_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HFS4043102.1"
                     /translation="MSDKFGEGRDPYLYPGLDIMRNRLNIHQQQRLEQAAYEMTALRA
                     ATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNAL
                     MQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
                     SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE"
     gene            complement(20333..20500)
                     /gene="yhfG"
                     /locus_tag="ACHY1N_000758"
     CDS             complement(20333..20500)
                     /gene="yhfG"
                     /locus_tag="ACHY1N_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HFS4043103.1"
                     /translation="MKKLTDKQKSRLWELQRNRNFQASRRLEGVEMPLVTLTAAEALA
                     RLEELRRHYER"
     gene            complement(20605..21177)
                     /gene="ppiA"
                     /locus_tag="ACHY1N_000759"
                     /gene_synonym="rotA"
     CDS             complement(20605..21177)
                     /gene="ppiA"
                     /locus_tag="ACHY1N_000759"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HFS4043104.1"
                     /translation="MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELEL
                     DKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPSKPVVILSAKVLP"
     gene            21448..22629
                     /gene="tsgA"
                     /locus_tag="ACHY1N_000760"
     CDS             21448..22629
                     /gene="tsgA"
                     /locus_tag="ACHY1N_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HFS4043105.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAA
                     MFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSI
                     EWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTV
                     LAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVL
                     TCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTS
                     H"
     gene            22891..25434
                     /gene="nirB"
                     /locus_tag="ACHY1N_000761"
     CDS             22891..25434
                     /gene="nirB"
                     /locus_tag="ACHY1N_000761"
                     /EC_number="1.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-nitrite reductase large subunit"
                     /protein_id="HFS4043106.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFY
                     DKLIMATGSYPWIPPIKGSDTEDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEA
                     AGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGV
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDI
                     YAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEIYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPAHSGSGKPSIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLAKHGKGYGCEVCKPTVGSLLASCWNEYILKPEHTPLQDSNDNFLANIQKDGTYS
                     VIPRSPGGEITPEGLMAVGRIAREFNLYTKITGSQRLAMFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGLGVELENRYKGIRTPHKMKFGVSGCT
                     RECSEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADIDRETLIKYLDRFMMFY
                     IRTADKLTRTAPWLENLEGGIDYLKAVIIDDKLGLNAHLEEEMARLREAVVCEWTETV
                     NTPSAQTRFKHFINSDKRDPNVQMVPEREQHRPATPYERIPVTLVEDNA"
     gene            25431..25757
                     /gene="nirD"
                     /locus_tag="ACHY1N_000762"
     CDS             25431..25757
                     /gene="nirD"
                     /locus_tag="ACHY1N_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HFS4043107.1"
                     /translation="MSQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSDQVFAISN
                     IDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYEARVKDG
                     VVQLRG"
     gene            25884..26690
                     /gene="nirC"
                     /locus_tag="ACHY1N_000763"
     CDS             25884..26690
                     /gene="nirC"
                     /locus_tag="ACHY1N_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026212.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HFS4043108.1"
                     /translation="MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIIL
                     IFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTFGVKAGSISHGQMW
                     AILPQTWLGNLVGSVFVAMLYSWGGGSLLPVDTSIVHSVALAKTTAPAMVLFFKGALC
                     NWLVCLAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSIANMTLFALSWFGNHSEAYT
                     LAGIGHNLLWVTLGNTLSGAVFMGLGYWYATPKANRPVADKFNQTETAAG"
     gene            26709..28082
                     /gene="cysG"
                     /locus_tag="ACHY1N_000764"
     CDS             26709..28082
                     /gene="cysG"
                     /locus_tag="ACHY1N_000764"
                     /EC_number="1.3.1.76"
                     /EC_number="2.1.1.107"
                     /EC_number="4.99.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0043115 - precorrin-2 dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0051266 - sirohydrochlorin ferrochelatase
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="siroheme synthase CysG"
                     /protein_id="HFS4043109.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALA
                     FIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQ
                     LRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQ
                     KLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
                     LNWFSNH"
     gene            28329..28496
                     /gene="yhfL"
                     /locus_tag="ACHY1N_000765"
     CDS             28329..28496
                     /gene="yhfL"
                     /locus_tag="ACHY1N_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
                     /protein_id="HFS4043110.1"
                     /translation="MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISIS
                     KIIGGCGPTAQ"
     gene            28791..30128
                     /gene="frlA"
                     /locus_tag="ACHY1N_000766"
     CDS             28791..30128
                     /gene="frlA"
                     /locus_tag="ACHY1N_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417829.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine/psicoselysine transporter"
                     /protein_id="HFS4043111.1"
                     /translation="MGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWL
                     TVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDA
                     PSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAK
                     IIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMT
                     GEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKLANSETPISDALTWIPAL
                     GSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSI
                     ILQGAQGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGL
                     MTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS"
     gene            30149..31171
                     /gene="frlB"
                     /locus_tag="ACHY1N_000767"
     CDS             30149..31171
                     /gene="frlB"
                     /locus_tag="ACHY1N_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417830.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-phosphate deglycase"
                     /protein_id="HFS4043112.1"
                     /translation="MLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHTIVEEMVKRDI
                     DRIYFVACGSPLNAAQTAKHLADRFSDLQVYAISGWEFCDNTPYRLDDRCAVIGVSDY
                     GKTEEVIKALELGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHLLLCYSVV
                     LEMITRLAPNAEIGKIKNDLKQLPNALGHLVRTWEEKGRQHGELASQWPMIYTVAAGP
                     LRPLGYKEGIVTLMEFTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTER
                     AINFVKQRTDNVIVIDYAEISQGLHPWLAPFLMFVPMEWLCYYLSIYKDHNPDERRYY
                     GGLVEY"
     gene            31221..32051
                     /gene="frlC"
                     /locus_tag="ACHY1N_000768"
     CDS             31221..32051
                     /gene="frlC"
                     /locus_tag="ACHY1N_000768"
                     /EC_number="5.1.3.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 3-epimerase"
                     /protein_id="HFS4043113.1"
                     /translation="MKTGMFTCGHQRLPIEHAFRDASELGYDGIEIWGGRPHAFAPDL
                     KAGGIKQIKALAQTYQMPIIGYTPETNGYPYNMMLGDEHMRRESLDMIKLAMDMAKEM
                     NAGYTLISAAHAGYLTPPNVIWGRLAENLSELCEYAENIGMDLILEPLTPYESNVVCN
                     ANDVLHALALVPSPRLFSMVDICAPYVQAEPVMSYFDKLGDKLRHLHIVDSDGASDTH
                     YIPGEGKMPLRELMRDIIDRGYDGYCTVELVTMYMNEPRLYARQALERFRALLPEDER
                     "
     gene            32048..32833
                     /gene="frlD"
                     /locus_tag="ACHY1N_000769"
     CDS             32048..32833
                     /gene="frlD"
                     /locus_tag="ACHY1N_000769"
                     /EC_number="2.7.1.218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HFS4043114.1"
                     /translation="MKTLATIGDNCVDIYPQLNKAFSGGNAVNVAVYCTRYGIQPGPI
                     TWVGDDDYGTKLKQDLARMGVDISHVHTKHGVTAQTQVELHDNDRVFGDYTEGVMADF
                     ALSEEDYAWLAQYDIVHAAIWGHAEDAFPQLHAAGKLTAFDFSDKWDSPLWQTLVPHL
                     DFAFASAPQEDEALRLKMKAIVARGAGTVIVTLGENGSIAWDGAQFWRQAPEPVTVID
                     TMGAGDSFIAGFLCGWSAGMTLPQAMAQGTACAAKTIQYHGAW"
     gene            32933..33664
                     /gene="frlR"
                     /locus_tag="ACHY1N_000770"
                     /gene_synonym="yhfR"
     CDS             32933..33664
                     /gene="frlR"
                     /locus_tag="ACHY1N_000770"
                     /gene_synonym="yhfR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417834.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator FrlR"
                     /protein_id="HFS4043115.1"
                     /translation="MSATDRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQ
                     YNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKVENALLTVSGFTDFGVSQGKATK
                     EKVIEQERVSAAPFCEKLNIPGNSEVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEI
                     YVEGSSTYQLFQERFDTRVVSDKKTIDIFAATRPQAKWLKCELGEPLFRISKIAFDQN
                     DKPVHVSELFCRANRITLTIDNKRH"
     gene            complement(33816..34901)
                     /gene="yhfS"
                     /locus_tag="ACHY1N_000771"
     CDS             complement(33816..34901)
                     /gene="yhfS"
                     /locus_tag="ACHY1N_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFS4043116.1"
                     /translation="MKTFPLQSLTIIEAQQKQFALVDSICRHFPGSEFLTGGDLGLTP
                     GLNQPRVTQRVEQVLADAFHAQAAALVQGAGTGAIRAGLAALLKPGQRLLVHDAPVYP
                     TTRVIIEQMGLTLITVDFNDLSALKQVVDEQQPDAALVQHTRQQPQDSYVLADVLATL
                     RAAGVPALTDDNYAVMKVARIGCECGANISTFSCFKLFGPEGVGAVVGDADVINRIRA
                     TLYSGGSQIQGAQALEVLRGLVFAPVMHAVQAGVSERLLALLNGGAVPEVKSAVIANA
                     QSKVLIVEFHQPIAARVLEEAQKRGALPYPVGAESKYEIPPLFYRLSGTFRQANPQSE
                     HCAIRINPNRSGEETVLRILRESIASI"
     gene            complement(34913..36217)
                     /gene="yhfT"
                     /locus_tag="ACHY1N_000772"
     CDS             complement(34913..36217)
                     /gene="yhfT"
                     /locus_tag="ACHY1N_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfT family protein"
                     /protein_id="HFS4043117.1"
                     /translation="MDLYIQIIVVACLTGMTSLLAHRSAAVFHDGIRPILPQLIEGYM
                     NRREAGSIAFGLSIGFVASVGISFTLKTGLLNAWLLFLPTDILGVLAINSLMAFGLGA
                     IWGVLILTCLLPVNQLLTALPVDVLGSLGELSSPVVSAFALFPLVAIFYQFGWKQSLV
                     AAVVVLMTRVVVVRYFPHLNPESIEIFIGMVMLLGIAITHDLRHRDENDIDASGLSVF
                     EERTSRIIKNLPYIAIVGALIAAVASMKIFAGSEVSIFTLEKAYSAGVTPEQSQTLIN
                     QAALAEFMRGLGFVPLIATTALATGVYAVAGFTFVYAVGYLSPNPMVAAVLGAVVISA
                     EVLLLRSIGKWLGRYPSVRNASDNIRNAMNMLMEVALLVGSIFAAIKMAGYTGFSIAV
                     AIYFLNESLGRPVQKMAAPVVAVMITGILLNVLYWLGLFVPA"
     gene            complement(36229..36582)
                     /gene="yhfU"
                     /locus_tag="ACHY1N_000773"
     CDS             complement(36229..36582)
                     /gene="yhfU"
                     /locus_tag="ACHY1N_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2620 domain-containing protein"
                     /protein_id="HFS4043118.1"
                     /translation="MKKIGVAGLQREQIKKTIEATAPGSFEVFIHNDMEAAMKVKSGQ
                     LDYYIGACNTGAGAALSIAIAVIGYNKSCTIAKPGIKAKDEHIAKMIAEGKVAFGLSV
                     EHVEHAIPMLINHLK"
     gene            complement(36593..37471)
                     /gene="php"
                     /locus_tag="ACHY1N_000774"
     CDS             complement(36593..37471)
                     /gene="php"
                     /locus_tag="ACHY1N_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase-related protein"
                     /protein_id="HFS4043119.1"
                     /translation="MSFDPTGYTLAHEHLHIDLSGFKNNVDCRLDQYAFICQEMNDLM
                     TRGVRNVIEMTNRYMGRNAQFMLDVMRETGINVVACTGYYQDAFFPEHVATRSVQELA
                     QEMVDEIEQGIDGTDLKAGIIAEIGSSEGKITPLEEKVFIAAALAHNQTGRPISTHTS
                     FSTMGLEQLALLQAHGVDLSRVTVGHCDLKDNLDNILKMIDLGAYVQFDTIGKNSYYP
                     DEKRIAMLHALRDRGLLNRVMLSMDITRRSHLKANGGYGYDYLLTTFIPQLRQSGFSQ
                     ADVDVMLRETPSQFFQ"
     gene            complement(37468..38694)
                     /gene="yhfW"
                     /locus_tag="ACHY1N_000775"
     CDS             complement(37468..38694)
                     /gene="yhfW"
                     /locus_tag="ACHY1N_000775"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFS4043120.1"
                     /translation="MARFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQ
                     LPTLEKLGLINALGYAPGDMQPSDSATWGVAELQHEGGDTFMGHQEILGTRPLPPLRM
                     PFRDVIDRVEQALVSAGWQVERRGDDLQFLWVNQAVAIGDNLEADLGQVYNITANLSV
                     ISFDDAIKIGRIVREQVQVGRVITFGGLLTDSQRILDAAESKEGRFIGINAPRSGAYD
                     NGFQVVHMGYGVDEKVQVPQKLYEAGVPTVLVGKVADIVSNPYGVSWQNLVDSQRIMD
                     ITLDEFNTHPTAFICTNIQETDLAGHAEDVARYAERLQVVDRNLARLVEAMQPDDCLV
                     VMADHGNDPTIGHSHHTREVVPVLVYQQGMIATQLGVRTTLSDVGATVCEFFRAPPPQ
                     NGRSFLSSLRFAGDTL"
     gene            complement(38694..39857)
                     /gene="yhfX"
                     /locus_tag="ACHY1N_000776"
     CDS             complement(38694..39857)
                     /gene="yhfX"
                     /locus_tag="ACHY1N_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfX family PLP-dependent enzyme"
                     /protein_id="HFS4043121.1"
                     /translation="MFVEALKRQNPALISAALSLWQQGKIAPDSWVIDVDQILENGKR
                     LIETARLYGIELYLMTKQFGRNPWLAEKLLALGYSGIVAVDYKEARVMRRAGLPVAHQ
                     GHLVQIPCHQVADAVEQGTDVITVFTLDKAREVSAAAVKAGRIQSVLLKVYSDDDFLY
                     PGQESGFVQHSLHEVVAEIKKLPGLHLAGLTHFPCLLWDEAAGKVLPTPNLHTLVQAR
                     DQLAKSGIVIEQLNAPSATSCTSLPLLAQYGVTHAEPGHALTGTIPANQQGDQSERIA
                     MLWLSEISHHFRGDSYCYGGGYYRRGHAQHALVFTPENQKITETNLKTVDDSSIDYTL
                     SLAGEFPVSSAVVLCFRTQIFVTRSDVVLVSGIHRGEPKIVGRYDSLGNSLGA"
     gene            complement(39941..40303)
                     /gene="yhfY"
                     /locus_tag="ACHY1N_000777"
     CDS             complement(39941..40303)
                     /gene="yhfY"
                     /locus_tag="ACHY1N_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417841.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4043122.1"
                     /translation="METRLNLLCEAGVIDKDICKGMMQVVNVLETECHLPVRSEQGTM
                     AITHMASALMRSRRGEEIEPLDNELLAELAQSSHWQAVVQLHQVLLKEFALEVNPCEE
                     GYLLANLYGLWMAANEEV"
     gene            complement(40320..41225)
                     /gene="yhfZ"
                     /locus_tag="ACHY1N_000778"
     CDS             complement(40320..41225)
                     /gene="yhfZ"
                     /locus_tag="ACHY1N_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator YhfZ"
                     /protein_id="HFS4043123.1"
                     /translation="MRRTFIKKEGVVITTLARYLLGEKCGNRLKTIDELATECRSSVG
                     LTQAALKTLESSGAIRIERRGRNGSYLVEMDNKALLSHVDINNVVCAMPLPYTRLYEG
                     LASGLKAQFDGIPFYYAHMRGADIRVECLLNGVYDMAVVSRLAAESYLTQKGFCLALE
                     LGPHTYVGEHQLICRKGESANVKRVGLDNRSADQKIMTDVFFGDSDVERVDLSYHESL
                     QRIVKGDVDAVIWNVVAENELTMLGLEATPLTDDPRFLQATEAVVLTRADDYPMQQLL
                     RAVVDKHALLAHQQRVVSGEQEPSY"
     gene            complement(41494..42498)
                     /gene="trpS"
                     /locus_tag="ACHY1N_000779"
     CDS             complement(41494..42498)
                     /gene="trpS"
                     /locus_tag="ACHY1N_000779"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFS4043124.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNALYGEIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASVHASRTLKAVYEAIGFVAKP
                     "
     gene            complement(42491..43249)
                     /gene="gph"
                     /locus_tag="ACHY1N_000780"
     CDS             complement(42491..43249)
                     /gene="gph"
                     /locus_tag="ACHY1N_000780"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008967 - phosphoglycolate phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HFS4043125.1"
                     /translation="MNKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEE
                     RVITWIGNGADVLMERALTWARQERATQRKTMGKPPVDDDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGG
                     DDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     AIDLSQPDVIYQSINDLLPALGLPHSENQESKND"
     gene            complement(43242..43919)
                     /gene="rpe"
                     /locus_tag="ACHY1N_000781"
     CDS             complement(43242..43919)
                     /gene="rpe"
                     /locus_tag="ACHY1N_000781"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFS4043126.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
                     VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSE
                     LAKVSHE"
     gene            complement(43937..44773)
                     /gene="dam"
                     /locus_tag="ACHY1N_000782"
     CDS             complement(43937..44773)
                     /gene="dam"
                     /locus_tag="ACHY1N_000782"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HFS4043127.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVE
                     RHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPA
                     KK"
     gene            complement(44880..46166)
                     /gene="damX"
                     /locus_tag="ACHY1N_000783"
     CDS             complement(44880..46166)
                     /gene="damX"
                     /locus_tag="ACHY1N_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_process: GO:0032506 - cytokinetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HFS4043128.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDI
                     ELDDTDDRRPTRAQKERNEEPEIEEEIDESEDETVDEERVERRPRKRKKAASKPASRQ
                     YMMMGVGILVLLLLIIGIGSALKAPSTSSSDQTASGEKSIDLAGNATDQANGVQPAPG
                     TTSAENTQQDVSLPPISSTPTQGQTPAATDGQQRVEVQGDLNNALTQPQNQQQLNNVA
                     VNSTLPTEPATVAPVRNGNASRETAKTQTAERPATTRPARQQAVIEPKKPQATVKTEP
                     KPVAQTPKRTEPAAPVASTKAPAATSTPATKETATTAPVQTASPAQTTATPAAGGKTA
                     GNVGSLKSAPSSHYTLQLSSSSNYGNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGV
                     YASKEEAKKAVSTLPADVQAKNPWAKPLRQVQADLK"
     gene            complement(46258..47346)
                     /gene="aroB"
                     /locus_tag="ACHY1N_000784"
     CDS             complement(46258..47346)
                     /gene="aroB"
                     /locus_tag="ACHY1N_000784"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFS4043129.1"
                     /translation="MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNET
                     LAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVAL
                     GGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAA
                     RTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLIL
                     PLAIGKSEVRSGVSHELVLNAIADCQSA"
     gene            complement(47403..47924)
                     /gene="aroK"
                     /locus_tag="ACHY1N_000785"
     CDS             complement(47403..47924)
                     /gene="aroK"
                     /locus_tag="ACHY1N_000785"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HFS4043130.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            complement(48325..49563)
                     /gene="hofQ"
                     /locus_tag="ACHY1N_000786"
     CDS             complement(48325..49563)
                     /gene="hofQ"
                     /locus_tag="ACHY1N_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HFS4043131.1"
                     /translation="MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQE
                     KLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEDNILSVHSIAWQNNNIA
                     RQEAEQARAQANLPLENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
                     KTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTT
                     LGSDLSVATATTHVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDG
                     KEDERRELVVFITPRLVSSE"
     gene            complement(49475..49879)
                     /gene="hofP"
                     /locus_tag="ACHY1N_000787"
     CDS             complement(49475..49879)
                     /gene="hofP"
                     /locus_tag="ACHY1N_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417851.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofP"
                     /protein_id="HFS4043132.1"
                     /translation="MRVKRWLLAGIALCLLTGMRDPFKPPEDLCRISELSQWRYQGMV
                     GRGERIIGVIKDGQKKWRRVQQNDVLENGWTILQLTPDALTLGTGTNCEPPQWLWQRQ
                     GDTNEAMDSRTTVDADTRRTGGKAAKSDADGG"
     gene            complement(49869..50309)
                     /gene="hofO"
                     /locus_tag="ACHY1N_000788"
     CDS             complement(49869..50309)
                     /gene="hofO"
                     /locus_tag="ACHY1N_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofO"
                     /protein_id="HFS4043133.1"
                     /translation="MNMFFDWWFATSPRLRQLCWAFWLLMLVTLIFLSSTHHEERDAL
                     IRLRASHHQQWAALYRLVDTTPFSEEKTLPFSPLDFQLSGAQLVSWHPSAQGGELALK
                     TLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG"
     gene            complement(50293..50832)
                     /gene="hofN"
                     /locus_tag="ACHY1N_000789"
     CDS             complement(50293..50832)
                     /gene="hofN"
                     /locus_tag="ACHY1N_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofN"
                     /protein_id="HFS4043134.1"
                     /translation="MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTS
                     SAEARVDAVLLQGEQQLAHSLQITKPRLLERQQIREQRLQRQRQRQFTRDWQSALEAL
                     AALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLRQDASFHLNQRGATQQDAQ
                     GRWQFEYQLTRKVSDEHVL"
     gene            complement(50832..51611)
                     /gene="hofM"
                     /locus_tag="ACHY1N_000790"
     CDS             complement(50832..51611)
                     /gene="hofM"
                     /locus_tag="ACHY1N_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HFS4043135.1"
                     /translation="MAFKIWQIGLHLQQQEAVAVAIVRGAKECFLQRWWRLPLENDII
                     KDGRIVDAQQLAKTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQTAWL
                     SGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPD
                     ASALQRFLPFLPSHQQCLAWRDNEQWLWATRYRWGRKLAVGMTSAKELAAALSVDPES
                     VAICGEGGFDPWEAVSVRQPPLPPSGGDFAIALGLALGKAY"
     gene            51731..54283
                     /gene="mrcA"
                     /locus_tag="ACHY1N_000791"
     CDS             51731..54283
                     /gene="mrcA"
                     /locus_tag="ACHY1N_000791"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417855.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HFS4043136.1"
                     /translation="MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNN
                     KITDTLKALPTYGPLLPAAVTSANPQQATAMLADGSTVALSMEGVRWARPYRSDTQQG
                     PTPRKVTDVLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSDWQPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDT
                     QKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF"
     gene            complement(54448..55008)
                     /gene="nudE"
                     /locus_tag="ACHY1N_000792"
     CDS             complement(54448..55008)
                     /gene="nudE"
                     /locus_tag="ACHY1N_000792"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HFS4043137.1"
                     /translation="MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRP
                     TNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGF
                     GANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLE
                     DPDFNEARNVSALFLVREWLKGQGRV"
     gene            55328..57463
                     /gene="igaA"
                     /locus_tag="ACHY1N_000793"
     CDS             55328..57463
                     /gene="igaA"
                     /locus_tag="ACHY1N_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HFS4043138.1"
                     /translation="MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRK
                     LTPEERSAVENYLESLTQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGIST
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIYTDSLPLVISLNGHTLQEYMQETR
                     GYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFF
                     CLITPDVFVPWLAGGALLLLGAGLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQE
                     QINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHVVRQGRYLSLHDEVKNFPL
                     QHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRV
                     GDTLRISGTGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATAL
                     TEAVNRQLHPKPEDESRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCSAKDDCVRLK
                     NALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITHETARA
                     AQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNA
                     EGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQR
                     HRTRMMEIQAYYESCLNPQLITPSESLIE"
     gene            57528..58196
                     /gene="yrfG"
                     /locus_tag="ACHY1N_000794"
     CDS             57528..58196
                     /gene="yrfG"
                     /locus_tag="ACHY1N_000794"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HFS4043139.1"
                     /translation="MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNG
                     VTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFL
                     EALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAE
                     ATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLI
                     PSLM"
     gene            58207..58608
                     /gene="hslR"
                     /locus_tag="ACHY1N_000795"
     CDS             58207..58608
                     /gene="hslR"
                     /locus_tag="ACHY1N_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HFS4043140.1"
                     /translation="MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAALLYEETAESVEKREKMAMAR
                     KLNALTMPHPDRRPDKKERRDLLRFKHGDSE"
     gene            58633..59511
                     /gene="hslO"
                     /locus_tag="ACHY1N_000796"
     CDS             58633..59511
                     /gene="hslO"
                     /locus_tag="ACHY1N_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFS4043141.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNV
                     LAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENA
                     DLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEV
                     TVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(59646..61370)
                     /gene="yhgE"
                     /locus_tag="ACHY1N_000797"
     CDS             complement(59646..61370)
                     /gene="yhgE"
                     /locus_tag="ACHY1N_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
                     /protein_id="HFS4043142.1"
                     /translation="MDNVELSPATRWGMIATGLLQGLVCYLLIAWLAGKNHSWIVYGV
                     PATVAFSSVLLFSVISFKQKRLWGWLALVFIATLGMSGWLKWQTDGMNPWRAEKALWD
                     FGCYLLLMAMLLLPWIQQSLRIRNDSSRYRYFYQSVWHNVLILLVIFLANGLTWLVLL
                     LWSELFKLVGITFFNTLFFATDWFIYLTLGLVTALAVILARTQSRLIDSIQKLFTLIA
                     TGLLPLVSLLTLMFIITLPFTGLSAISRHISAAGLLLTLAFLQLILMAIVRDPQKASL
                     PWTGPLRCLIKTALLVAPLYVFVAAWALWLRVAQYGWTVDRLQGVLAVLVLLVWSLGY
                     FVSIVWRKGQNPVVLQGKVNLAVSLLVLVILVLLNSPVLDSMRISVNSHMARYQSGKN
                     TSDQVTIYMLEQSGRYGRAALESLKSDAGFMKDPKRARDLLMALDGEQHLQEQVSEKV
                     LAENVLIAPGSVKPDATFWSALIQDRYNVMTCIEKDACVLVEQDLNSDGQAERILFAF
                     NDDRVIVYGFDSDRKEWDALDMSLLPNEITKEKLLTAAKDGKLGTRPKAWRDLTVDGE
                     TLEINLSK"
     gene            61748..63370
                     /gene="pckA"
                     /locus_tag="ACHY1N_000798"
     CDS             61748..63370
                     /gene="pckA"
                     /locus_tag="ACHY1N_000798"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFS4043143.1"
                     /translation="MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGY
                     ERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETW
                     QHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEEL
                     AGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSM
                     MNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDD
                     GVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRV
                     SYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLA
                     GTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRI
                     SIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQE
                     KAETLAKLFIDNFDKYTDTPAGAALVAAGPKL"
     gene            complement(63446..64798)
                     /gene="envZ"
                     /locus_tag="ACHY1N_000799"
     CDS             complement(63446..64798)
                     /gene="envZ"
                     /locus_tag="ACHY1N_000799"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HFS4043144.1"
                     /translation="MRRLRFSPRSSFARTLLLIVTLLFASLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYSNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEE
                     CNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIETALYPGSIEVKMHP
                     LSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVR
                     GDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKEG
                     "
     gene            complement(64795..65514)
                     /gene="ompR"
                     /locus_tag="ACHY1N_000800"
     CDS             complement(64795..65514)
                     /gene="ompR"
                     /locus_tag="ACHY1N_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HFS4043145.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            65742..66218
                     /gene="greB"
                     /locus_tag="ACHY1N_000801"
     CDS             65742..66218
                     /gene="greB"
                     /locus_tag="ACHY1N_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312275.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HFS4043146.1"
                     /translation="MKTPLVTREGYEKLKQELNYLWREERPEVTKKVTWAASLGDRSE
                     NADYQYNKKRLREIDRRVRYLTKCMENLKIVDYSPQQEGKVFFGAWVEIENDDGVTHR
                     FRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPAGEASWYVNAIEYVKP"
     gene            66315..68636
                     /gene="yhgF"
                     /locus_tag="ACHY1N_000802"
     CDS             66315..68636
                     /gene="yhgF"
                     /locus_tag="ACHY1N_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417866.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFS4043147.1"
                     /translation="MMNDSFCRIIAGEIQARPEQVDAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLSYLRELEERRQAILKSISEQGKLTDDLAKAINATLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWSDPSHTPEVAAAQYVDADKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVSTVVSGKEEEGAKFRDYFDHHEPLSTV
                     PSHRALAMFRGRNEGVLQLSLNADPQFDEPPKESYCEQIIMDHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDATGKLVATDTIYPHTGQAAKAAMTVAALCEKHNVELVAIGNGTASR
                     ETERFYLDVQKQFPKVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFKNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSSELRNLKASDFTDEKFGVPTVTDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLQPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSNKFVEDPHTVVKAGDIVKVKVLEVDLQRKRIALTMRLDEQPGETNARRGGGNERPQ
                     NNRPAAKPRGREAQPAGNSAMMDALAAAMGKKR"
     gene            69074..69301
                     /gene="feoA"
                     /locus_tag="ACHY1N_000803"
     CDS             69074..69301
                     /gene="feoA"
                     /locus_tag="ACHY1N_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HFS4043148.1"
                     /translation="MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALLEVEAVSC"
     gene            69318..71639
                     /gene="feoB"
                     /locus_tag="ACHY1N_000804"
     CDS             69318..71639
                     /gene="feoB"
                     /locus_tag="ACHY1N_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312278.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HFS4043149.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQ
                     FSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
                     LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAY
                     AGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDK
                     IVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSL
                     KDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQHPTYSLVCILAVILFNIVVIG
                     LLRRARSRVDIELLATRKSVSSCCAASTTGDCH"
     gene            71639..71875
                     /gene="feoC"
                     /locus_tag="ACHY1N_000805"
     CDS             71639..71875
                     /gene="feoC"
                     /locus_tag="ACHY1N_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HFS4043150.1"
                     /translation="MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMG
                     KAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR"
     gene            72078..72956
                     /gene="rpnA"
                     /locus_tag="ACHY1N_000806"
     CDS             72078..72956
                     /gene="rpnA"
                     /locus_tag="ACHY1N_000806"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnA"
                     /protein_id="HFS4043151.1"
                     /translation="MSKKQSSTPHDALFKLFLRQPDTARDFLAFHLPAPIHALCDMKT
                     LKLESSSFIDDDLRESYSDVLWSVKTEQGPGYIYCLIEHQSTSNKLIAFRMMRYAIAA
                     MQNHLDAGYKTLPMVVPLLFYHGIESPYPYSLCWLDCFADPKLARQLYASAFPLIDVT
                     VMPDDEIMQHRRMALLELIQKHIRQRDLMGQVEQMACLLSSGYANDRQIKGLFNYILQ
                     TGDAVRFNDFIDGVAERSPKHKESLMTIAERLRQEGEQSKALHIAKIMLESGVPLTDI
                     MRFTGVSEEELAAASQ"
     gene            complement(72985..73755)
                     /gene="bioH"
                     /locus_tag="ACHY1N_000807"
     CDS             complement(72985..73755)
                     /gene="bioH"
                     /locus_tag="ACHY1N_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HFS4043152.1"
                     /translation="MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHL
                     VDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQAL
                     VTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARA
                     LKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPML
                     DKLWPHSESYIFAKAAHAPFISHPVEFCHLLVALKQRV"
     gene            73793..74476
                     /gene="gntX"
                     /locus_tag="ACHY1N_000808"
     CDS             73793..74476
                     /gene="gntX"
                     /locus_tag="ACHY1N_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417872.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HFS4043153.1"
                     /translation="MLTVPGLCWLCRMPLALGHWGICSVCSRAARTDKTLCPQCGLPA
                     THSHLPCGRCLQKPPPWQRLVTVADYAPPLSPLIHQLKFSRRSEIASALSRLLLLEVL
                     HARRTTGLQLPDRIISVPLWQRRHWRRGFNQSDLLCQPLSRWLHCRWDSKAVTRTRAT
                     ATQHFLSARLRKRNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAATV
                     QVWCLCRTL"
     gene            74535..75110
                     /gene="nfuA"
                     /locus_tag="ACHY1N_000809"
     CDS             74535..75110
                     /gene="nfuA"
                     /locus_tag="ACHY1N_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA];
                     GO_process: GO:0051604 - protein maturation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HFS4043154.1"
                     /translation="MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            75471..76787
                     /gene="gntT"
                     /locus_tag="ACHY1N_000810"
     CDS             75471..76787
                     /gene="gntT"
                     /locus_tag="ACHY1N_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HFS4043155.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEE
                     MPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNI
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI"
     gene            complement(76832..78916)
                     /gene="malQ"
                     /locus_tag="ACHY1N_000811"
     CDS             complement(76832..78916)
                     /gene="malQ"
                     /locus_tag="ACHY1N_000811"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HFS4043156.1"
                     /translation="MESKRLDNAALAAGISPNYINAYGKPQSISAETKRRLLDAMHQR
                     TATKVAVTPVPNVMVYTSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPT
                     KLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWG
                     IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNA
                     VEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDHE
                     QMTAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFC
                     EEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDREL
                     YCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHV
                     MSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGK
                     LRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWESGDLTLGKT
                     LGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRY
                     IADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWRRKLSATLESMFADDGVNKLLKD
                     LDRRRRAAAKKK"
     gene            complement(78926..81319)
                     /gene="malP"
                     /locus_tag="ACHY1N_000812"
     CDS             complement(78926..81319)
                     /gene="malP"
                     /locus_tag="ACHY1N_000812"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008184 - glycogen phosphorylase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HFS4043157.1"
                     /translation="MSQPIFNDKQFQEALSRQWQRYGLNSAAEMTPRQWWLAVSEALA
                     EMLRAQPFAKPVANQRHVNYISMEFLIGRLTGNNLLNLGWYQDVQDSLKAYDINLTDL
                     LEEEIDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPD
                     DWHRSNYPWFRHNEALDVQVGIGGKVTKDGRWEPEFTITGQAWDLPVVGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGDFLRAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEK
                     VWAKLAVVHDKQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWIKQCNPALAALLDKSLQKEWANDLDQLINLEKFADDAKFRQQYREIKQANK
                     VRLAEFVKVRTGIEINPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     QVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGDKHAFDQMLHSIGKQGGDPYL
                     VMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            81931..84636
                     /gene="malT"
                     /locus_tag="ACHY1N_000813"
     CDS             81931..84636
                     /gene="malT"
                     /locus_tag="ACHY1N_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HFS4043158.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYG
                     KTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQY
                     ASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGW
                     ATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAI
                     LRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQW
                     ELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSL
                     LEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAE
                     FNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSL
                     ALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGD
                     LDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFA
                     NNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     AGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRI
                     LREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV"
     gene            complement(84679..85695)
                     /gene="rtcA"
                     /locus_tag="ACHY1N_000814"
     CDS             complement(84679..85695)
                     /gene="rtcA"
                     /locus_tag="ACHY1N_000814"
                     /EC_number="6.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003963 - RNA-3'-phosphate cyclase
                     activity [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
                     /protein_id="HFS4043159.1"
                     /translation="MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAK
                     PGLLRQHLTAVKAAAEICRATVEGAELGSQRLVFRPGIVRGGEYRFAIGSAGSCTLVL
                     QTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFY
                     PAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSL
                     HEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLAS
                     PAAVGEYLADQLVLPMALAGAGEFKVAHPSCHLLTNIAVVERFLPVRFGLIETDGVTR
                     VSIE"
     gene            complement(85699..86925)
                     /gene="rtcB"
                     /locus_tag="ACHY1N_000815"
     CDS             complement(85699..86925)
                     /gene="rtcB"
                     /locus_tag="ACHY1N_000815"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-splicing ligase RtcB"
                     /protein_id="HFS4043160.1"
                     /translation="MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIA
                     VMPDVHLGKGSTIGSVIPTKGAIIPAAVGVDIGCGMNALRTALTAEDLPENLAELRQA
                     IEMAVPHGRTTGRCKRDKGAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHL
                     GTLGTGNHFIEICLDESDQVWIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRD
                     LAYFMEGTEYFDDYLKAVAWAQLFASLNRDAMMENVVTALQSITQKTVRQPQTLAMEE
                     INCHHNYVQKEQHFGEEIYVTRKGAVSARAGQYGIIPGSMGAKSFIVRGLGNEESFCS
                     CSHGAGRVMSRTKAKKLFSVEDQIRATAHVECRKDAEVIDEIPMAYKDIDAVMAAQSD
                     LVEVIYTLRQVVCVKG"
     gene            87114..88712
                     /gene="rtcR"
                     /locus_tag="ACHY1N_000816"
     CDS             87114..88712
                     /gene="rtcR"
                     /locus_tag="ACHY1N_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RtcR"
                     /protein_id="HFS4043161.1"
                     /translation="MRKTVAFGFVGTVLDYAGRGSQRWSKWRPTLCLCQQESLVIDRL
                     ELLHDTRSRSLFETLKRDIASVSPETEVVGVEIELHNPWDFEEVYACLHDFARGYEFQ
                     PEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQSSPPRKKEQPRGAGEVTIIDLD
                     LSRYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTG
                     AGKSFLARRIFELKQARHQFSGAFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREG
                     LLRSANGGMLFLDEIGELGADEQAMLLKAIEEKTFYPFGSDRQVSSVFQLISGTVRDL
                     RQLVAEGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHATLTGDSVRFNTE
                     ARRAWLAFATSPQATWRGNFRELSASVTRMATFATSGRITLDVVEDEINRLRYNWQES
                     RPSALTALLGAEAENIDLFDRLQLEHVIALCRQAKSLSAAGRLLFDVSRQGKASVNDA
                     DRLRKYLARFGLTWEAVQDQHSSS"
     gene            complement(88694..89452)
                     /locus_tag="ACHY1N_000817"
     CDS             complement(88694..89452)
                     /locus_tag="ACHY1N_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HFS4043162.1"
                     /translation="MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELA
                     EQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTT
                     PEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
                     SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDAPPPVSVMQVLTDHHIQLELC"
     gene            complement(89469..90299)
                     /gene="glpG"
                     /locus_tag="ACHY1N_000818"
     CDS             complement(89469..90299)
                     /gene="glpG"
                     /locus_tag="ACHY1N_000818"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HFS4043163.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQ
                     AERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVVMI
                     ACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
                     "
     gene            complement(90344..90670)
                     /gene="glpE"
                     /locus_tag="ACHY1N_000819"
     CDS             complement(90344..90670)
                     /gene="glpE"
                     /locus_tag="ACHY1N_000819"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004792 - thiosulfate sulfurtransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HFS4043164.1"
                     /translation="MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAVQAFHLT
                     NDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPA
                     EVAYGA"
     gene            90860..92365
                     /gene="glpD"
                     /locus_tag="ACHY1N_000820"
     CDS             90860..92365
                     /gene="glpD"
                     /locus_tag="ACHY1N_000820"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HFS4043165.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDEGM
                     HLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLKVYNAHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIE
                     GDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGAISDLGEDFGHEFYEAE
                     LKYLVDHEWVRRTDDALWRRTKQGMWLNADQQSRVSQWLVEYTQQKLSLAS"
     gene            complement(92417..93022)
                     /locus_tag="ACHY1N_000821"
     CDS             complement(92417..93022)
                     /locus_tag="ACHY1N_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000589351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043166.1"
                     /translation="MIKFRLYIPPVILGFVIVPLLVWPTVIVLAVLIFTLTFLAEIIF
                     SFPLLVVRISLQELQLELMVEYALFFSVMAGIGWQFSRRTPPELKNRLHCWLVFSPVY
                     FWLILSNFILYISPEKSALLENIRNFFLTFVWPPLNFSPFWPQPWTDFVGPISAQLGF
                     ALGYYCHWCRKNRNQRKKWGDWVTCLSLAILAQGPLFNYLQ"
     gene            complement(93025..93792)
                     /locus_tag="ACHY1N_000822"
     CDS             complement(93025..93792)
                     /locus_tag="ACHY1N_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001182130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043167.1"
                     /translation="MQPSPAMQALIEQIYHTFRRYRVPQKFVVCCEYCLSQQEQKALR
                     STSLRAIPYSLINAWNSSPGPDPQNSDEVRYFLPRLLEFVAQGHFDNIHVVFSLRRIN
                     LASKENWREDEWKILQRFACQYMTDWVSGDETVELQYMLEMFFRADIALAPLLDAINS
                     VPGFWSTVSLACLLNRYCEDYIRDNQDDIDNVITTQINAWAFNNQSILKERARQAIEN
                     PPKQPEQGTQHQVWVDDWIIDECLCAMYDASSESPGK"
     gene            complement(93795..94505)
                     /locus_tag="ACHY1N_000823"
     CDS             complement(93795..94505)
                     /locus_tag="ACHY1N_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043168.1"
                     /translation="MELVNTLFASLAGTDPFTGVDITIANCKSAYWDEGIVQQLINQA
                     LDEGEKFVGADGLEGLLRYNVTLNIGLTSSNVWPGFSLDTATISRLCACGADFGFDPY
                     ISDVPDVQCDLNTTNDVTVQFTAMLNPDERVIIAKRPLKKCDSWIEDVYIFQVFKDAW
                     KFHNNNSLRGFRDKQAELKLYTRHYSVENCAEESCRDCNSCIRPSFSLSRSALIRLNA
                     ANARFVYQPFTRDQRARG"
     gene            complement(94521..96029)
                     /locus_tag="ACHY1N_000824"
     CDS             complement(94521..96029)
                     /locus_tag="ACHY1N_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001443257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFS4043169.1"
                     /translation="MMQNRKWILTSLVMTFFGIPILAQFLAAVIAMLGVGLAGIIEVC
                     NIFITPTIYLLLNIFMLALGALMLFFSGRVWADDSAPEKREIAVWRQCLFLVPALLTL
                     GVWIIALHLADYQFHQMGAGWLADLMLPWLGVLLASLVGGEYWWLVIIPVGAHISFSL
                     GYGWPTRYPLTGTSGLRCRNSLLFILLMLGFVAGYQAYLYKQLNPGVGVRENIDTWAW
                     RPDKLNNQLTPLRGKPQIQFTQNWPRLDGATAAYPIYASAFYALSVLPEDFHEWEYLA
                     NSRTPEAYNKIVKGNADIIFVAQPSGGQKKRAEESGVTLIYTPFAREAFVFIVNADNP
                     VNSLTEQQVRDIFSGAITNWRTVGGNDQEIQTWQRPEDSGSQTVMQSQVMKNVRMISP
                     QETEVASMMEGMIKVVAEYRNTNNAIGYTFRYYATQMNDDKNIKLLAINGIAPTAENI
                     RNGKYPYIVDAFMVTRENTTSETQKLLEWFLTPQGQSLVEDVGYVPMYKTLP"
     gene            complement(96154..98601)
                     /gene="glgP"
                     /locus_tag="ACHY1N_000825"
     CDS             complement(96154..98601)
                     /gene="glgP"
                     /locus_tag="ACHY1N_000825"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008184 - glycogen phosphorylase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HFS4043170.1"
                     /translation="MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGAL
                     EAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQ
                     IIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRL
                     LIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNELQQHCD
                     FPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEML
                     DHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDR
                     TIKEYADHIWHIDPVRL"
     gene            complement(98620..100053)
                     /gene="glgA"
                     /locus_tag="ACHY1N_000826"
     CDS             complement(98620..100053)
                     /gene="glgA"
                     /locus_tag="ACHY1N_000826"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HFS4043171.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAF
                     PDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFA
                     YTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAEN
                     KRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            complement(100053..101348)
                     /gene="glgC"
                     /locus_tag="ACHY1N_000827"
     CDS             complement(100053..101348)
                     /gene="glgC"
                     /locus_tag="ACHY1N_000827"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HFS4043172.1"
                     /translation="MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVF
                     DADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRD
                     VGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER"
     gene            complement(101366..103339)
                     /gene="glgX"
                     /locus_tag="ACHY1N_000828"
     CDS             complement(101366..103339)
                     /gene="glgX"
                     /locus_tag="ACHY1N_000828"
                     /EC_number="3.2.1.196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004133 - glycogen debranching enzyme
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HFS4043173.1"
                     /translation="MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQE
                     HRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDG
                     EFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKG
                     LTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNY
                     WGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPL
                     FSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFR
                     FDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEW
                     NDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDC
                     VCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVE
                     NRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPA
                     GEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR"
     gene            complement(103336..105522)
                     /gene="glgB"
                     /locus_tag="ACHY1N_000829"
     CDS             complement(103336..105522)
                     /gene="glgB"
                     /locus_tag="ACHY1N_000829"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HFS4043174.1"
                     /translation="MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDAT
                     DVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFG
                     PLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
                     GRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETAS
                     LICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYA
                     KWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVIL
                     DWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALY
                     WIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQV
                     SGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLT
                     FGILYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLL
                     FMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPY
                     GFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTD
                     SMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE"
     gene            complement(105795..106898)
                     /gene="asd"
                     /locus_tag="ACHY1N_000830"
     CDS             complement(105795..106898)
                     /gene="asd"
                     /locus_tag="ACHY1N_000830"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFS4043175.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAA
                     PSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLR
                     MKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVAT
                     YQAASGGGARHMRELLTQMGHLYGHVADELATPSSAILDIERKVTTLTRSGELPVDNF
                     GVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQ
                     AFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRK
                     LNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            107091..107684
                     /gene="yhgN"
                     /locus_tag="ACHY1N_000831"
     CDS             107091..107684
                     /gene="yhgN"
                     /locus_tag="ACHY1N_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YhgN"
                     /protein_id="HFS4043176.1"
                     /translation="MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVREL
                     LIALLVMLVFLFAGEKILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAG
                     EEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
                     RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG"
     gene            complement(107730..109025)
                     /locus_tag="ACHY1N_000832"
     CDS             complement(107730..109025)
                     /locus_tag="ACHY1N_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312307.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990814 - DNA/DNA annealing activity
                     [Evidence IEA];
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFS4043177.1"
                     /translation="MDADSSDSTVTPGRLPDGLSSCPCFYLGKKLMNLSANAQATLLL
                     TSDFSRAAASEHKPLSNSEWGKFALWLKHQRISPAELLVPQPQEKLTGWSDPRISQER
                     ILGLLARGHSLALAVDKWQRAGLWIITRGDADYPVRLKNRLRTDAPPVLFGCGNKALL
                     QAEGMAIVGSRDAPTDDLRYTQQLAAKLAQQGICVISGGARGIDECAMASALEAGGTA
                     VGVLADSLLKTSTLVKWREGLIAGNLVLISPFYPEVRFTVGNAMARNKYIYCLAESAM
                     VVRAGMTGGTITGAIEALKHQWLPVQVKPNQDMQSANSRLVENGASWSAEQAENVPIR
                     LSDVPGLMYDRALRNAQPELFSLHENDANYAVMPAHTPVDFYQLFVAELAIFAKESIS
                     IERLSSCTGLTIEQISVWLNRAEEEGRVIRLGEGHYQFR"
     gene            complement(108932..111028)
                     /locus_tag="ACHY1N_000833"
     CDS             complement(108932..111028)
                     /locus_tag="ACHY1N_000833"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RecQ family ATP-dependent DNA helicase"
                     /protein_id="HFS4043178.1"
                     /translation="MEKHAAELLLQRMLGNTTATFREGQWEAIDAVVNQRRKLLVVQR
                     TGWGKSAVYFIASKIFRDRGAGPTIIISPLLALMRNQVAAAERLGITAETLNSTNREE
                     WQRISDKLLQGEVDCLLVSPERLANQDFIETVLYPIADRIGLLVVDEAHCISDWGHDF
                     RPDYRRILDILRQLPANTPVLGTTATANNRVVEDIRQQLGDIVIQRGTLARESLALDA
                     LVLGEQSSRLAWLATVIPQFSKSGIVYTLTTRDADLVAEWLRTNGISAFAYYSGVTCE
                     GAEDSNTAREYLEQALLANKIKVLVATTALGMGFDKPDLGFVIHYQMPGSIVGYYQQV
                     GRAGRAIDSAVGILLCGGEDRAIHKFFRESAFPAEAQIHEILNVLSENDGLTLRGIEQ
                     RTNLRYGQIEKALKLLVAENPSPVVYTEKLWRRTIVSFSPDHERINHLMNQRKNELAD
                     VESYITTKECKMQFLRRALDEPSAERCGKCSSCLQHPLLSPDIDSGLLHAANLFIKHA
                     DLPLNLNKKVASGAFTQYGFKGNLPAGLQGSTGRVLSRWGDSGWGKQVAQEKKTGRFS
                     DELVEACAEMVRQRWNPHPEPTWVCCVPSLRHLDLVPDFARRLAAKLGLPFIDAIEKV
                     VDNPPQKMQQNRFHQCQNLDGAFVITPPLMPGPALLVDDIVDSAWTLTVLTALLRQAG
                     CPTVYPLALASTSVKN"
     gene            complement(111168..112508)
                     /gene="gntU"
                     /locus_tag="ACHY1N_000834"
     CDS             complement(111168..112508)
                     /gene="gntU"
                     /locus_tag="ACHY1N_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HFS4043179.1"
                     /translation="MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRAH
                     YAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVP
                     GPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPIIEQLNYSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(112512..113039)
                     /gene="gntK"
                     /locus_tag="ACHY1N_000835"
     CDS             complement(112512..113039)
                     /gene="gntK"
                     /locus_tag="ACHY1N_000835"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFS4043180.1"
                     /translation="MSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHP
                     RRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLREGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQPL
                     EGVVASTIEVIKKGK"
     gene            complement(113178..114173)
                     /gene="gntR"
                     /locus_tag="ACHY1N_000836"
     CDS             complement(113178..114173)
                     /gene="gntR"
                     /locus_tag="ACHY1N_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate operon transcriptional repressor GntR"
                     /protein_id="HFS4043181.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSQSPCLDIAV
                     GFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVE
                     QSSSYSSGIELIRQARREYPQLDGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLDLGFTLSPGGSI"
     gene            complement(114397..115092)
                     /gene="yhhW"
                     /locus_tag="ACHY1N_000837"
     CDS             complement(114397..115092)
                     /gene="yhhW"
                     /locus_tag="ACHY1N_000837"
                     /EC_number="1.13.11.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="HFS4043182.1"
                     /translation="MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVIN
                     DDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHS
                     EYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHAD
                     SDSEVLLFDLPPV"
     gene            complement(115215..116252)
                     /gene="yhhX"
                     /locus_tag="ACHY1N_000838"
     CDS             complement(115215..116252)
                     /gene="yhhX"
                     /locus_tag="ACHY1N_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFS4043183.1"
                     /translation="MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQ
                     APIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTL
                     AQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGD
                     LKAIVKTSHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGV
                     LEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITHGAPNYVKESEVLTNLEILERGFE
                     QASPSTVTLAK"
     gene            116584..117072
                     /gene="yhhY"
                     /locus_tag="ACHY1N_000839"
     CDS             116584..117072
                     /gene="yhhY"
                     /locus_tag="ACHY1N_000839"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HFS4043184.1"
                     /translation="MSEIVIRHAETRDYEAIRQIHAQPEVYCNTLQVPHPSDHMWQER
                     LADRPGIKQLVACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMRE
                     MIEMCDNWLRVDRIELTVFVDNAPAIKVYKKYGFEIEGTGKKYALRNGEYVDAYYMAR
                     VK"
     gene            117309..>117582
                     /gene="tssD"
                     /locus_tag="ACHY1N_000840"
     CDS             117309..>117582
                     /gene="tssD"
                     /locus_tag="ACHY1N_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein TssD"
                     /protein_id="HFS4043185.1"
                     /translation="MSNIVYLTVTGEQQGSISAGCGTSESTGNRWQSGHEDEIFTFSL
                     LNNINNTGLGSQFHGITFCKLIDKSTPLFINSINNNEQLFMGFDFYR"
BASE COUNT        28478 a        31888 c        29467 g        27749 t
ORIGIN      
        1 tattcaacgt gagaagtgtt gatggtgata ccacgagctt tttcttccgg cgcgttatcg
       61 atctggtcga atgcacgagc agcaccgccg taggttttag ccagtacggt ggtgattgca
      121 gcggtcagag tagttttacc gtggtcaacg tggccgatag taccaacgtt aacgtgcggt
      181 tttgtacgtt caaatttttc tttagacacg gctatattcc ttactatagt gctctcccct
      241 tcaggagaga gcacgggact ttggtattaa cccttaggct tatttaccac gggcttcaat
      301 tacggcctga gcaacgttac tcggcgcttc atcatacttc aggaattcca tagtgtatga
      361 tgcacgacct ttggtcagag aacgcagctg agttgcgtat ccgaacattt cagacagcgg
      421 tacttcagcg tggatcttaa cgccagtaac ttcagattcc tgacctttga gcataccacg
      481 acgacggctc aagtcaccga taacgtcacc ggtgttctct tccggagttt ctacttcaac
      541 cttcatgatc ggctcaagca gaactggttt cgctttctta aagccttctt taaaggcgat
      601 agaagcagcc agtttaaacg ccagttcaga ggagtcaacg tcatggtaag aaccgaagtg
      661 cagacgaata cccatgtcta ctaccgggta gcctgccagc ggacctgctt tcagctgttc
      721 ctggatacct ttatcaacgg ccgggatgta ttcgccaggg attacaccac ctttaatgtc
      781 gttgatgaac tcgtagcctt tcgggtttga acccggctcc agcgggtaca tgtcgataac
      841 aacatgacca tactgaccac gaccaccaga ctgtttcgcg tgtttacctt caacatcggt
      901 aactttctgg cggatagttt cacggtaagc aacctgcggt ttacctacgt tcgcttcaac
      961 gttgaattca cgcttcatac ggtcaacgat gatgtcgagg tgcagttcgc ccatacccgc
     1021 gataatggtc tggttagatt cttcgtcagt ccatacacgg aaagacgggt cttctttagc
     1081 cagacggccc agagccagac ccattttttc ctggtcagct ttggttttcg gttcaactgc
     1141 gatggagatt accggctcag ggaattccat acgttccaga atgatcggcg catccgggtc
     1201 acacagggtg tcaccagtgg ttacgtcttt cagaccgata gcagcagcga tgtcgcccgc
     1261 gcgaacttct ttgatctctt cacgtttgtt agcgtgcatc tgaacgatac gaccgaaacg
     1321 ctcacgtgca gctttcacgg agttcagtac ggtatcacca gagttaacca caccggagta
     1381 aacacggaag aaggtcaggt taccaacaaa cgggtcggta gcgattttga acgccagtgc
     1441 agaaaacggc tcgtcatcac ttgcgtgacg ctcagccgga gtgtctttac cgtcgtccag
     1501 gataccgttg atcgcaggta cgtcaaccgg ggatggcagg taatcaatta ccgcatccag
     1561 catcgcctga acacctttgt tcttgaacgc agaaccacag gttaccagga tgatttcgtt
     1621 gttcagaacg cgctgacgca gagcaccttt gatttctgct tcagtcagtt cttcaccacc
     1681 caggtatttt tccatcagct cttcagaagc ttcagctgcg gattcgatca ggttctggtg
     1741 ccattcgtta gccagttcaa ccatgtctgc cgggatatct tcgtattcga aggttacgcc
     1801 ctggtcagcg tcgttccagt tgatagcttt cattttcacc aggtcaacaa caccggtgaa
     1861 atgttcttca gcaccaatcg ccagctgcag cggaaccggg ttcgcgccca gacgggtttt
     1921 gatctggtta acaactttca ggaagttcgc acccatgcgg tccattttgt taacgaacgc
     1981 aatgcgcgga actttatatt tgtttgcctg acgccatacg gtttcagact gcggctgaac
     2041 accaccaact gcgcagtaaa ccattaccgc accatcgaga acacgcatgg aacgttctac
     2101 ttcgattgtg aagtcaacgt gccccggggt gtcgatgatg ttgatgcgat gcggctcata
     2161 ctgcttagcc ataccagacc agaatgcagt agtcgcagcg gaagtgatgg taataccacg
     2221 ttcctgctcc tgctccatcc agtccatggt tgcagcgccg tcatgaactt caccgatttt
     2281 atggtttaca ccggtgtaga acagaatacg ttcggtagta gtggttttac cggcgtcgat
     2341 gtgcgcactg ataccgatat tacggtagcg tgcgatgggt gttgtacgag ccatttgttt
     2401 cctcgtttat cttttaggcg ttcaatttaa gtagcccaaa gcgggctgct tactggaagc
     2461 gcccgcctgg tgactaaaac tccgaaggga ttaccaacgg tagtgtgcga acgccttgtt
     2521 ggcttcggcc atacggtgaa cgtcttcacg tttcttaact gcagtacctt tgttttctgc
     2581 agcatcagaa agttcgttcg ccaggcgcag agccatggat ttatcaccgc gtttacgagc
     2641 agcttcaacg atccaacgca ttgccagagc attacgacga accggacgga cttcaactgg
     2701 tacctgataa gtagaaccac caacgcggcg agacttaact tctacagtcg ggcgcacgtt
     2761 ttcgagagct acttcgaatg cttccagttc agatttacca gagcgctgag ccagggtctc
     2821 cagcgcgctg tatacgatag attcagcagt agatttttta ccatctacca tcaggatatt
     2881 tacaaattta gccagcagtt ctgatccgaa cttcggatcc ggcagaattt tacgctgacc
     2941 aatgacgcga cgacgtggca tggaaatact ccgttgttaa ttcaggattg tccaaaactc
     3001 tacgagttta gtttgacatt taagttaaaa cgtttggcct tacttaacgg agaaccatta
     3061 agccttagga cgcttcacgc catacttgga acgagcctgc ttacggtctt taacgccgga
     3121 gcagtcaagc gcaccacgta cggtgtggta acgaacaccc gggaggtctt taacacgacc
     3181 gccacggatc aggatcacgg agtgctcctg caggttgtga ccttcaccac cgatgtagga
     3241 agtcacttcg aaaccgttag tcagacgaac acggcatact ttacgcagcg cggagttcgg
     3301 ttttttagga gtggtagtat atacacgagt acatacgcca cgtttttgcg ggcatgcttc
     3361 cagcgcaggc acgttgcttt tcgcaacttt gcgagcacgt ggtttgcgta ccagctggtt
     3421 aactgttgcc attaaatagc tcctggtttt agcttttgct tcgtaaacac gtaataaaac
     3481 gtcctcacac aatatgagga cgccgaattt tagggcgatg ccgaaaaggt gtcaagaaat
     3541 atacaacgat cccgccatca ccaggccatc tggctggagt gcttaaccgt aagtctgacg
     3601 aaatcagtat agtcaatggg aatgatgtcg ttcgaaattt gaccagtcaa accgcgggca
     3661 ataaggtctt cgttcagggc atagacctta atgggggcat tacgcagact ttcaaggtag
     3721 cggttaccgt caactgcggc agttacgcca tcttgcaata atagcagttc gtctccttca
     3781 ctgagcagac gcagcagcgc agcaaaatcc gtcagccagg gtgaacgatg taacgtgtgc
     3841 agcataaacg cctcaaaacc tcaaaataac atcgtagttg gcgagttcgc ggcgtaaggc
     3901 atctgcttcg agcggcgtgg cttcgacaac aaagggtgtc tgcggatcta acccgcgttc
     3961 gcgcagtgaa gccgcacaaa cccagcactg ttcaatgtcg tacagaccca acaatttaaa
     4021 agtggcaatg taatcacgcg ccagcactgc atcgggcttt tgtcctgaca gcagctgaaa
     4081 aacgccatca gcaataaaga agacggccag atcgtcagtt aatgcggaag ttgccagtaa
     4141 agcatctaaa ccttcccgac cagcagctgt accatgaggt gcagtagaaa aaacaaacgc
     4201 aattcgtttc atcagaactg taccaccctg tcataggtca gcgaggcttc cgccagcgcg
     4261 ccaagtccgc ttaaggtaaa tcccggctga aggtttgacg aagccagccc cagccttcct
     4321 gcttcagttt catcgacgat accgcggcgt aacgctgccg ctacgcagat attcagcgcc
     4381 acaccatgtt gcgcattcaa ctgttgccag ccgcgcacaa ggtcaaattc gtcacttgcc
     4441 ggtgaggtca attggttagc gttatagacc ccttcccgat agaaaaagac gctgcttaac
     4501 tcatggcctt ctactatcag cgcctgcgca aactgaaaag cactactcgc ctgttgcgta
     4561 ccgtatgctg gcccggtcac cacgatggca aaacgcatta cttatcttgc ccctggaaat
     4621 caccgctttt gaactggcgg atgtagagat agacagtgtg tttggagatg ttcaggcggt
     4681 cagcaacctg gttgatcgcg tctttaatat cgaagatccc tttctcgtag agattcagca
     4741 cgatctgacg atttttggcg ttattagaaa cattgcgatc ggcattcact tcttcgatgg
     4801 tgaactccag cgtttgggta accagatctt caacagaaga ggcaaagttg acgcttgaac
     4861 cgacatccgg ggtttctggc ggcacaaaag tgctcataat ctgcgagaag ggaacatcaa
     4921 gattcatatt gatgcacagc agaccaatta cacgctgttc gcggttacga atcgcgatag
     4981 tcagggactt cattaatacg ccgcttttgg cgcgagtaaa gtagcattta gaaacgctgc
     5041 tatccgctcc cgtcatatcg tgcagcatac gtagcgccag gtcagtaatt ggcgaaccaa
     5101 tcttccggcc tgtatgttca ccgttagcaa tgcgaatggc tgaacatttt agatcctgca
     5161 aagagtgcaa aacgatttca cagtgggagc caataagcat cgctaacccg tccaccaccg
     5221 cttcgtagga tttcagaata tcaaaatcgg tctggtcgaa aggacgttga tccagtaaat
     5281 ccaactcact ggtttcgttg gttaaaagcg acctggacat gaaaaaaaac actccttttc
     5341 aggagcctgt cgttaacttt tcagggcagg ctcattaatg atgcgggtaa ctaaattaat
     5401 acagcggagg ttccgctttc cagcactaat tatatccggc ctgtaataaa aaaaccgccg
     5461 cctggtcagg cggcggttct taatgcttat tttttagcag aatctgcggc tttcgcatca
     5521 gcttccggct ttgcatcagc cttcggcgct ggtttcacat ccagcagctc tacgtcaaac
     5581 accagggtag aattcggtgg gatccccgga acacccgctt tgccgtaagc cagttctggt
     5641 ggaataacca gtttgatctt accgcctttc ttgatgttct tcagaccttc tgtccaaccc
     5701 gggataacac cgtccagacg gaaagaaagc ggttcaccac gggtgtaaga gttgtcgaac
     5761 tctttaccgt cgatcagcgt acctttgtag ttcactacaa cagtatcgct gtctttcggt
     5821 gcttcgcctt taccggcttc tactacctga taaaccagac cagttgaaga ggttttcaca
     5881 cctttctctt tggcaaattt ctcgcggtac tctttacctt ttgcttcgtt atcagccgcg
     5941 tctttttcca tcttcgcctg agcagaagac ttcacgcgag cttcgaatgc ttgcagagtc
     6001 tgttcgatct cttggtcgga gagtttgctc ttatcagcaa atgcatcctg aacaccagcg
     6061 atcagctgat ctttatccag tttgatgccc agtttttctt gttctttaag agagttttcc
     6121 atgtaacgac ccagcgaagc acccagtgca taagctgatt tctgatcgtc atttttgaac
     6181 gctgctttgc tgtcagcagt tgtagcaggt tttgcagctt cagcagcaaa agtgattggt
     6241 gcatgcaggg caacggccat tgtggtcgcc agcagcgtta ctttaaacag tgatttcatc
     6301 catatctcca ggatcggggc atctcacccc agggttaact attatcagaa gggtactata
     6361 aagcgttgtc gaacaaatct acatacagac acgccctatt atcatctatt ttcagactct
     6421 ttttgtttaa attagtttcg atgaccgcga aatgagtgct gtctcgggca gcaaagttaa
     6481 gtagaatccg cggcgaccat tcgacaaaag aggtgaatca tgcaggattt atcattggaa
     6541 gcacgcctgg cagagctgga gagccgactg gcttttcagg aaatcaccat tgaagaactg
     6601 aacgtcacgg tgaccgctca tgaaatggag atggcgaaac tgcgcgatca tctgcgtctg
     6661 ctgaccgaga agttaaaagc cagccagccg tcgaacatcg cgtcgcaggc tgaagaaacg
     6721 ccaccgccac attattgagg cgtaaaaaaa gcggggattc cccgcttttt tgtcaccttt
     6781 tcggtattag tggcaaccac aaccgccgtt gcctttaccg ccacagcagc cttcgccacc
     6841 gtgttcatga ccgtgatcgt ggccatgacc gccgcagcaa ccgtcgtggt cgtgatcgtg
     6901 gtgatgatcg tgcgcgccgt gaacgtggcc atgagccagt tcttcttcgg tcgcttcgcg
     6961 aatcgccaca acttcaacgt tgaatttcag gttctgaccg gccagcatgt ggttaccatc
     7021 aaccacgacg tgatcgtctt caaccgcagt gatttcaacc ggtaccggac cctggtcagt
     7081 ttcagccagg aaacgcatac ctacctgcag ttcatcaacg cccataaata cgtctttagg
     7141 aacacgttgc accaggtttt cgtcgtactg accgtaagcg tcgttcgcgc caacagcgac
     7201 atcaaatttg tcgccaactt catgaccttc cagcgccgtt tccaggccag agatcaggga
     7261 accgtgacca tgcaggtagt ccagcggcgc actcaccgga gactcatcaa ccaacacacc
     7321 gtcttctgta cgtacctgat aggccaggct gaccaccagg tcttttgcta ctttcatgat
     7381 atctcctgag catgggaaga atagtggcgc agattgtagc ggaattctgc agccgtgtac
     7441 tcactagctt aaaaaaactc ggcgcatatc gctagtccgg atgaaaaatc ccgatcactt
     7501 gctcatcttt gcgaacgtga tcgcgggctt ctttgtctgc ttctcgcatc tgatgtccgc
     7561 acttaacaca ttcaacaata tcaatattat tttcgcgcca catcgccatt gaatcctgcg
     7621 cctgacaggc cgggcatttt gcgcccgcaa taaaacgttt tcggattgcc atctttaccc
     7681 tctactcaaa ttcatcccag ccgtccagct ggcgtcgttc ttgttgcatt tcacgctgga
     7741 aaatctcttc cagttcgcgt cgggcttccc tggcgcgaga aatttgtacg gtatcagcat
     7801 gcatcgggat taactcccgc agcattcgca tatccaggcg gcgaaaatgc agttgcgccc
     7861 gctgtgcctg atgcggatgc atgccaagcg tgaccagcgt cttgcgcccc agctctaacg
     7921 cactggagaa tgtttcacgg gaaaactgcg tcacccctgc ctgtaataac tcatgcgctt
     7981 ccacacgtcc gcgcgctcgc gcaagaatat gcaaatgcgg aaagtgctgc tggcatattt
     8041 ccaccagctt catggtgtct tccggctcgt tacaggtaat gacgatagac tcagcggcct
     8101 ctgcacccgc agaacgtaaa agatcgacct gcgtggcgtc gccgtaataa actttgtagc
     8161 catatttacg catcaggtta acggcgctga tatcccgctc cagcacggta atgcgcattt
     8221 tatttgccat cagcaaacga ccaatcacct gaccaaaacg cccgaagccc acgacaatga
     8281 cctggggttt atcatcgttg acccacggtt tttcgtcttc ttcttccggt ccgttaaact
     8341 ggcgggatag ccatttatcc accagcttca tcagcaacgg cgtggtcatc atggaaagcg
     8401 tcaccgtcac cagcaacagc gccatctgat cgccctggaa taaacgttgt gaagaagcgg
     8461 tagaaaagag gacaaaggca aactcaccgc cctgactcaa cacgccagca aactgcatcc
     8521 gctctgagct acgcacgcca tacaatcgcg ccagcagata caacacgaga attttcaccg
     8581 ccaccagcac aaccacgctt atcactaccc acaacagatg ggtataaagc accccgagat
     8641 tgagcgacat gccgacagag ataaagaaca aaccgagcag caagcctttg aagggatcga
     8701 tagccgtttc cagttcatgg cgatattcac tttccgccag cagcacgccc gcaataaacg
     8761 taccgagcgc catcgacagc cccagcgcgt ccataaacaa tgcggaaccc aacaccaaca
     8821 gcagcgtcgc ggcggtgaac acttcccgca cgccagaagc tgcaataaaa cggaataccg
     8881 gacgcagtaa atagcgcccg ccaatcagca tgccgacaaa cgccagcacc ttcatgccga
     8941 tcttcatcca gtcgaaatgt tcgtctgccg aacccgccaa caacggcact aacgccagtg
     9001 ccgggatcac cgccagatcc tgaaacagca gaaccgaaaa cccgagctgc ccggattcgc
     9061 tgcgattcat ccctttctca cgcatcaatt gcaacgccat tgcagttgaa gacatcgcaa
     9121 ggccaatgcc accgacaacc gccgcctgcc aggcgaaatc cgtcagcatc aataatcccg
     9181 ccagcaacgc cgcgcttaac agcacctgtg ccgcgcctac gccaaaaatc gaacgccgca
     9241 gttgccaaag tttggaggga ttcaactcaa gaccgatgat aaacatcagg aataccacgc
     9301 cgagttccga aaagtggagg atctcatcga cgtcgctaat aaaccccagc ccccatgggc
     9361 caattgcaat tcctgccagc aaatatccca acacagcgcc aatacccagc cgcgatgcca
     9421 gcggcaccgc agccaccgcc gcgaagagaa acagcactcc tgcgagtaaa aaatcggaac
     9481 cttccatcag cggcctcctg gagacagcgg atttgccagc cagtcaccgt aggctctggc
     9541 gtgactcgcc agctcctgtg cgctttgccg tctcgcccag taaataatga tgggacttaa
     9601 ccaatgcatc cggcacatgc ccgccgccag ttcaaaggga cgcagaacat cgctcatcgg
     9661 gtagcgattc aatgcgtcat aacggtaagc actttccggc tcgccggtgg taatcacgct
     9721 acgccagtac tttcccacca gttggtttcc tcccggcccg ctggcaaaac cacgacttaa
     9781 tacccggtcc agccactctt tcagtagcgc cgggcagcta taggtataaa gaggatgctg
     9841 aaagacaatc acctcgtgct cgcgcagtaa tgcctgctca cgggggatat caataaaaaa
     9901 atcgggatag tgcgcataaa ggtcgtgcac ggtaacattg ctgagctgcg tggccggttt
     9961 aagcagtacc cggtttgcca ccgagtcctg agattccgga tgggcataca gcagcaaaac
    10021 tttcgctggc tgagacatca tccccctccc ggtatggttt ttgtgtatag tcgctgtttt
    10081 gggctaccat tgcgcccggt gcggcagctc gcccatacat tacattatca taatgataag
    10141 ttaacatagt ctgaacatac ggcgccttat gattgttttc tcctcgttac aaattcgtcg
    10201 cggcgtgcgc gtcctgctgg ataatgccac cgccaccatc aaccctgggc agaaagtcgg
    10261 cctggtgggt aaaaacggct gtggtaaatc taccctgctg gcattgctga aaaatgaaat
    10321 cagcgccgac ggcggcagct acacctttcc gggaagctgg caactggcgt gggtgaatca
    10381 ggaaacgccg gcgttaccgc aagcggcgct ggaatatgtc attgacggcg accgtgaata
    10441 tcgtcaacta gaagcgcagc tacacgacgc caacgaacgt aacgacgggc acgccattgc
    10501 gaccattcat ggcaagctgg atgctattga cgcatggagt attcgctccc gtgccgccag
    10561 cctgctgcac ggcctcggtt tcagcaatga acaactggag cgcccggtaa gtgatttctc
    10621 cggtggctgg cgtatgcgtc ttaaccttgc ccaggcgctg atttgccgtt cagacttgct
    10681 gctgctcgac gaaccgacta accacctcga tctcgatgcc gttatctggc tggaaaaatg
    10741 gttgaagagc tatcagggca cgctgatcct gatctctcac gaccgcgact tcctcgatcc
    10801 gatcgttgat aaaattattc atatcgaaca acaaagcatg ttcgagtaca ccggcaacta
    10861 cagttcgttt gaagtacagc gcgccacccg tctggcgcag caacaagcga tgtatgaaag
    10921 ccagcaggaa cgcgtagcgc atctgcaaag ttatatcgac cgtttccgtg ccaaagccac
    10981 caaagcgaag caggcccaga gccgcattaa gatgctcgag cgtatggagc tgattgcccc
    11041 cgcgcacgtc gacaacccgt tccgctttag cttccgcgcg ccggaaagcc tgccaaatcc
    11101 gttactgaag atggaaaaag tcagcgcggg ctatggcgat cgcattattc tcgactcgat
    11161 taaactgaac ctggtgcccg gctcgcgcat tggtctgtta ggccgcaacg gcgcgggtaa
    11221 atcgacatta atcaaactgt tagccggtga acttgcgcca gtcagcggtg aaattggtct
    11281 ggcgaaaggg atcaagctcg gctacttcgc ccagcatcaa cttgaatacc tgcgcgccga
    11341 cgaatcacct attcaacatc tggcacgttt agcgccgcag gagctggaac aaaaactgcg
    11401 tgactacctc ggcggctttg gtttccaggg cgataaagta accgaagaaa cgcgccgctt
    11461 ctcaggtggg gaaaaagccc gcctggtgct ggcattaatt gtctggcagc gtccgaatct
    11521 gctgctgctc gacgaaccga ctaaccacct tgacctcgac atgcgtcagg cactcaccga
    11581 agcattaatc gagtttgaag gcgcgctggt tgtcgtttcg cacgaccgtc atttgctgcg
    11641 ttccaccact gacgatctct acctggttca cgatcgtaaa gtcgaaccgt tcgatggcga
    11701 tctggaagat tatcaacagt ggttgagcga cgtacaaaag caggaaaacc agaccgacga
    11761 agcgccaaaa gagaacgcga acagcgccca ggcacgtaaa gatcagaagc gtcgggaagc
    11821 ggagctgcgt gcgcaaaccc agccgctgcg taaagagatt gcccgtctgg aaaaagagat
    11881 ggagaagctg aacgcgcaac tggcgcaggc ggaagagaaa ctcggcgaca gcgaactgta
    11941 tgaccagagc cgtaaagcgg agttgaccgc ctgcctgcaa cagcaagcca gcgccaaatc
    12001 cggcctggaa gagtgcgaaa tggcgtggct ggaagcccag gagcagcttg agcagatgct
    12061 gctggaaggc caaagcaact gatggcgcag ataacgacga ccgatgccaa tgaatttagc
    12121 agcagtgctg aattcacccc tatgcgcggc tttagcaatt gtcatctaca aactatgctg
    12181 ccgcgtttgt ttcgtcgtca ggtgaaattc accccgtact ggcagcggct ggagttgccc
    12241 gacggcgatt ttgtcgatct cgcgtggagt gaagaccccg cacaggcgaa acataaaccg
    12301 cgtttagtgg tgtttcacgg gctggaaggc agtctcaata gcccttacgc ccacggtctg
    12361 gttgaggcgg cgcaaaagcg cggctggctg ggcgtggtga tgcattttcg cggatgcagc
    12421 ggtgaaccaa accgtatgca ccgcatttac cattcgggcg aaaccgaaga cgccagttgg
    12481 tttttacgct ggctgcaacg cgaatttggt catgcgccaa cggctgccgt cggctattcg
    12541 ctcggcggta atatgctggc ctgtttgctg gcaaaggaag gcaatgatct cccggttgat
    12601 gcggcggtga ttgtctctgc gccgtttatg ctggaagcct gtagctatca tatggaaaag
    12661 ggcttttccc gcgtttatca gcgttacttg ctgaacctgt taaaagccaa tgccgcgcgc
    12721 aagctggcag cctaccccgg aacgctgccg attaatctcg cgcagttaaa atcggtacgt
    12781 cgcatccgtg aatttgacga tctcatcacc gccagaattc acggctacgc cgacgctatc
    12841 gactattatc gtcagtgtag cgccatgccg atgctgaacc ggatcgccaa accgacgctg
    12901 attattcacg ccaaagacga tccgtttatg gatcatcagg tgatcccgaa accggaaagt
    12961 ctccccccgc aggtggagta tcaactgact gaacatggcg gtcatgttgg ctttattggc
    13021 ggtacattac ttcatccgca aatgtggctg gagtcacgca ttcctgactg gttaacaacg
    13081 tatctggagg cgaaatcatg ttgattccgt ggcaagacct ctcccccgaa acgctggaaa
    13141 atttaattga aagctttgtg ttacgtgaag gcaccgatta tggtgaacat gagcgtacac
    13201 ttgaacagaa agtcgccgac gtcaaacgcc agctacagtg cggagaagcg gtgctggtat
    13261 ggtcggagct gcacgaaacg gtcaatatta tgccgcgcag tcagtttcgc gaataacctg
    13321 caaccgtcgg cggacgagat aataatgata gctaagtcat ggagttacta tgtctgccaa
    13381 acatccggtc attgcggtaa caggatccag cggcgcgggg accaccacca ccagcctcgc
    13441 gtttcgtaaa atattcgcgc agttaaatct gcatgcagct gaggtggaag gcgacagttt
    13501 tcaccgttac acccgcccgg aaatggacat ggcgatccgc aaagcgcgcg acgccgggcg
    13561 gcatatcagc tacttcggcc ccgaggctaa cgacttcggc ctgctggaac aaaccttcat
    13621 tgaatacggt cagagcggca aagggaaatc tcgcaaatat ctgcatacct acgacgaagc
    13681 cgtaccgtgg aatcaggtac cggggacatt caccccctgg caacctttac cggaacccac
    13741 tgatgtactg ttttatgaag gtttacacgg cggcgtagtc acgccacagc ataacgttgc
    13801 gcagcatgtg gacttactgg tcggcgtggt gcctatcgtt aaccttgagt ggattcaaaa
    13861 actgatccgc gacaccagcg agcgcgggca ctcacgagaa gcagtgatgg actcagtagt
    13921 gcgttcaatg gaagactata tcaactacat cacaccgcag ttttcccgca cccatcttaa
    13981 cttccagcgc gttcccaccg tcgacacttc aaacccgttc gcggcaaaag gtatcccgtc
    14041 gctcgatgaa agctttgtgg tgatccattt tcgtaatctg gaagggatcg atttcccctg
    14101 gctgctggcg atgttgcaag gctcattcat ttcccacatc aatacgttag tggtaccggg
    14161 cggcaaaatg ggtctggcaa tggaattaat tatgctgccg ctggtgcaac gattgatgga
    14221 aggaaagaaa atcgagtaac tctgctatta cgccggataa aatactatcc ggcttcacaa
    14281 cgggatagtt aaatcacgcg gcaaccactt catacgagtg agtaatattc accgcttttt
    14341 ccagcatcaa cgccactgaa caatatttct cagcagagag atcaaccgca cgcgcaaccg
    14401 ctgcgtcttt caggtcgcga ccggtgacga taaaatgcag attaatgtgc gtaaacaggc
    14461 gtggtgcctc ttcgcggcgt tcagaggtca attttacttc acaatcgacc acatcctgac
    14521 gccctttttg caggatagaa accacatcga tggcactgca accccccgcc gccatcaaca
    14581 ccatttccat cggacttggt gctttatcgc ctgagttgcc gtccattaaa atctgatgac
    14641 cagaggcgga ttcgcccaga aaaattaacc cttcgaccca cttcactcgc gcttgcattt
    14701 ttgctactcc actgcgtcaa ttttcctgac agagtacgcg tactaaccaa atcgcgcaac
    14761 ggaaggcgac ctgggtcatg ctgaagcgag acaccaggag acacaaagcg aaagctatgc
    14821 taaaacagtc aggatgctac agtaatacat tgatgtactg catgtatgca aaggacgtca
    14881 cattaccgtg cagtacagtt gatagcccct tcccaggtag cgggaagcat atttcggcaa
    14941 tccagagaca gcggcgttat ctggctctgg agaaagctta taacagagga taaccgcgca
    15001 tggtgcttgg caaaccgcaa acagacccga ctctcgaatg gttcttgtct cattgccaca
    15061 ttcataagta cccatccaag agcacgctta ttcaccaggg tgaaaaagcg gaaacgctgt
    15121 actacatcgt taaaggctct gtggcagtgc tgatcaaaga cgaagagggt aaagaaatga
    15181 tcctctccta tctgaatcag ggtgatttta ttggcgaact gggcctgttt gaagagggcc
    15241 aggaacgtag cgcatgggta cgtgcgaaaa ccgcctgtga agtggctgaa atttcgtaca
    15301 aaaaatttcg ccaattgatt caggtaaacc cggacattct gatgcgtctg tctgcacaga
    15361 tggcgcgtcg tctgcaagtc acttcagaga aagtgggcaa cctggcgttc ctcgacgtga
    15421 cgggccgcat tgcacagact ctgctgaacc tggcaaaaca accagatgct atgactcacc
    15481 cggacggtat gcaaatcaaa attacccgtc aggaaatcgg tcagattgtc ggctgttctc
    15541 gtgaaaccgt gggacgcatt ctgaagatgc tggaagatca gaacctgatc tccgcacacg
    15601 gtaaaaccat cgtcgtttac ggcactcgtt aatcccgtcg gagtggcgcg ttacctggta
    15661 gcgcgccatt ttgtttcccc cgatgtggcg cagactgatt tatcaccccg atatcaacta
    15721 tgcacttcga caaacgctgg tgctatgttt gcccgtggcc gttgggttaa tgcttggcga
    15781 attacgattc ggtctgctct tctctctcgt tcctgcctgt tgcaatattg caggccttga
    15841 tacgcctcat aaacgttttt tcaaacgctt aatcattggt gcgtcgctgt ttgccacctg
    15901 tagcttactg acacagctgc tactggcaaa agatgttccc ctgccctttt tgctgaccgg
    15961 attaacgctg gtacttggcg tcactgctga gttggggcca ttgcacgcaa aattgcttcc
    16021 cgcatcgctg ctggcagcca tttttaccct cagtctggcg ggatacatgc cggtctggga
    16081 accgttgctc atctatgcgt tgggcactct ctggtacgga ttgtttaact ggttttggtt
    16141 ctggatctgg cgcgaacaac cgctgcgcga gtcactaagt ctgctgtacc gtgaactggc
    16201 agattattgt gaagccaaat acagcctgct tacccagcac accgaccctg aaaaagcgct
    16261 gccgccgctg ctggtgcgcc agcaaaaagc ggtcgatcta attacccagt gctatcagca
    16321 aatgcatatg ctttccgcgc aaaataatac tgactacaag cggatgctgc gtattttcca
    16381 ggaggcgctg gatttacagg aacatatttc ggtcagtttg catcagccgg aagaggtgca
    16441 aaagctggtc gagcgtagcc atgcggaaga agttatccgc tggaatgcgc aaaccgtcgc
    16501 cgctcgcctg cgcgtgctgg ctgatgacat tctttaccat cgcctgccaa cgcgttttac
    16561 gatggaaaag caaattggcg cactggaaaa aatcgcccgc cagcatccgg ataatccggt
    16621 tgggcaattc tgctactggc atttcagccg catcgcccgc gtgctgcgca cccaaaaacc
    16681 gctctatgcc cgtgacttac tggccgataa acagcggcga atgccattac ttccggcgct
    16741 gaaaagttat ctgtcactaa agtctccggc gctacgcaat gccggacgac tcagtgtgat
    16801 gttaagcgtt gccagcctga tgggcaccgc gctgcatctg ccgaagtcgt actggatcct
    16861 gatgacggta ttgctggtga cacaaaatgg ctatggcgca acccgtctga ggattgtgaa
    16921 tcgctccgtg ggaaccgtgg tcgggttaat cattgcgggc gtggcgctgc actttaaaat
    16981 tcccgaaggt tacaccctga cgttgatgct gattaccacc ctcgccagct acctgatatt
    17041 gcgcaaaaac tacggctggg cgacggtcgg ttttactatt accgcagtgt ataccctgca
    17101 actattgtgg ttgaacggcg agcaatacat ccttccgcgt cttatcgata ccattattgg
    17161 ttgtttaatt gctttcggcg gtactgtctg gctgtggccg cagtggcaga gcgggttatt
    17221 gcgtaaaaac gcccatgacg ctttagaagc ctatcaggaa gcgattcgct tgattcttag
    17281 cgaggatccg caacctacgc cactggcctg gcagcgaatg cgggtaaatc aggcacataa
    17341 cactctgtat aactcattga atcaggcgat gcaggaaccg gcgtttaaca gccattatct
    17401 ggcagatatg aaactgtggg taacgcacag ccagtttatt gttgagcata ttaatgccat
    17461 gaccacgctg gcgcgggaac accgggcatt gccacctgaa ctggcacaag agtatttaca
    17521 gtcttgtgaa atcgccattc agcgttgtca gcagcgactg gagtatgacg aaccgggtag
    17581 ttctggcgat gccaatatca tggatgcgcc ggagatgcag ccgcacgaag gcgcggcagg
    17641 tacgctggag cagcatttac agcgggttat tggtcatctg aacaccatgc acaccatttc
    17701 gtcgatggca tggcgtcagc gaccgcatca cgggatttgg ctgagtcgca agttgcggga
    17761 ttcgaaggcg taatgcaggc taaaccatcg gataaggcat tcacgccgca tccgacatct
    17821 tttgcctgat gcttcgtatt tacgccccaa ccaccttcgc caccgcgtgg gcgaaacgtt
    17881 gcatcccttc atcgatatcc gcatcttcca ccaccagcga cggtgcaaaa cgcatcacat
    17941 ccggtccggc attcagcacc attacgccag cccctgcgcc cgcatacagg aaatcacgcg
    18001 cccgaccttt gaactgtggc ttaagctccg cgccaatcaa cagccccata ccgcgaatat
    18061 cgctaaacac atcgtactgc tgatcgatct tctgcagatg gtcaacaaaa cgctggcgtt
    18121 tcgcctgaat gccttccagc acttcagggg tattgatgat atcaaacgcc gcgcccgcta
    18181 ctgcacagga cagaggatta ccgccgtagg tggaaccgtg agaaccagga tgaaatgcag
    18241 aagcaatttc tgccgtggtc agcatggcgc taatcgggaa gccgccgcct aacgctttcg
    18301 cagaggtcag aatatccggc gtcacgccgt agtgcatgta agcaaacaaa tcgccggtcc
    18361 gccccatccc gcactgtact tcatcaaaca ccaataatgc ctgatgttga tcgcacagct
    18421 cgcgcaagcc ctgcaaaaac tctggcgtcg ctgccgtcac accgccctcg ccctggatcg
    18481 gctcaaccac caccgcacag gtgtgatcat ccatcaccgc tttcactgcg tggagatcgt
    18541 taaaaggaac gtggatgatg tctgccggtt ttggcccaaa gccgtcggaa tattttggct
    18601 gcccgcccac cgagacggta aacagcgagc gaccatgaaa agcgttatgg aaggcaataa
    18661 ttttggtttt gaacggacta tgacgcacac aggcgtaatg gcgtgccagt ttaaaggcgg
    18721 tttcgttagc ttccgtgccg gagttcataa acaccacgcg ttcggcaaac gtcgcctcaa
    18781 tcagtttgcg cccaagacgc agcgccggtt cattggtgaa aacgttactg atatgccaca
    18841 gagtttcgcc ctgggttttt aacgcgttca ccagcgcagg atggcaatgg cccaacgccg
    18901 taactgcaat gccacccgcg aaatcgacat actccttgcc ttgctgatcc cagattcggc
    18961 tgccctgacc ttttaccgga atgaactctg ccggagcata aatcggcagg atcacttcat
    19021 cgaaagtcgc gcgtgtaatt gctgtttgtt caattgccat ctcatgatca ccctgttacg
    19081 cataaataat tgtgaaatta taatcacaaa atatgcataa aaaatcacta aatggcaatc
    19141 agaaatcagc gatgcaggaa attagccagc agttgatgtc cttgttcgct aagaatactt
    19201 tctggatgga actgcacacc ttccagatcc cactggcgat ggcgaatccc cataatctcg
    19261 cgggtttcgc tccaggccgt cacgtcaaag cacgctggta atgagtcagg ttccaccacc
    19321 agcgaatggt agcgtgtcac ggtaagtgga tttgccagcc cccgaaatac gccctcaccg
    19381 ttatgtgtaa tcggcgaggt tttgccgtgc atgacctttg cggcgcgcac aactttaccg
    19441 ccaaatgcct gcgccattgc ctgatgaccg aggcagacgc caagaatcgg caagcgcccg
    19501 gcatagtggc gaataacgtc aagggagatc ccggcttcat ctggcgtaca ggggccaggt
    19561 gagatgacaa ttttttgtgg tttaagggcg tcgatatccg ccagcgtcaa cgcatcgttg
    19621 cgcttaacca gcacatccgc ccccagttca caaaagtact ggtagaggtt ccaggtaaaa
    19681 gaatcgtagt tatctataag caggatcatg gcggctccgg tacaaaagaa ccgcgctatt
    19741 ttactcagat tccccggctt cgcttaccac tttgctaaat atcatctgca gcgcggtgag
    19801 atcccccatt gccccactct gatttgcctg attccaggcc tctttttcga taccctgcca
    19861 gctcagttga tacccggcat gaatcgccag ttgctcgaag aagatccgct gtgccagacc
    19921 acttcccacc cggaagggat gcagcacgtt gatttcacaa tagtaatgcg ccagccgctc
    19981 gacgaacttc gctttctcca ggccaaccag ataaccttct tcctccagat cctgcatcag
    20041 ggcattgccc tctttttcga tataagcaaa gtggcagaac ggcgtatcgc cctgataaat
    20101 atcaacttca cgcagttgcc ccgcccagtc gaaaatatcc tgatacagct ggcgatggat
    20161 agtgcgcaaa tgcggtaaac cgcgcaccag cggaccaagc tcaatggtcg cagcacgcag
    20221 cgccgtcatt tcgtaagcgg cctgttccag ccgctgctgc tggtggatgt tcagccggtt
    20281 acgcatgata tcaaggccag gataaagata cggatcgcgc ccttcgccga atttatcgct
    20341 catagtgcct cctcagctct tcaaggcgcg ctaaagcctc tgcggcagta agagtgacta
    20401 aaggcatctc gacgccttca agacggcgac tggcctggaa attacgatta cgctgaagct
    20461 cccagagacg ggacttttgc ttatcggtga gtttcttcac ttgatgcctc cctgaacgtg
    20521 tccatttgcc acaagtataa gcggcaaatc cgggttacgc cgggagagca gaagcgcggg
    20581 caagattgcc cgcgcgaaaa atcattacgg caggacttta gcggaaagga taactaccgg
    20641 ttttgacggc acattctggt acggaccaac gtcatgagtc ggcacctggg aaatcttatc
    20701 ggcaacgtcc atgcctttca ccactttacc aaataccgcg taaccgaaat cacgctgacc
    20761 atggtcaagg aaggcgttat cggcaacgtt gataaagaac tggctggtgg cgctgtcttt
    20821 gtcagcggta cgcgccatcg cgatggtgcc acgcgtgttg cgcaggccgt tatcggcttc
    20881 atttttgatt ggcgggtttg gttttttctg ctgcatctgc tcggtgaaac cgccgccctg
    20941 aatcataaag ccaggaatga cgcggtgaaa ggtagtgttg ttataaaaac cgctgttcac
    21001 ataatcgaca aagttttgca cagacactgg cgctttttgt ttatccagct ccagttcgat
    21061 gttaccagct gaggttgtca acaatacgtg cgggtcccct ttcgctgcca ttgctgcggg
    21121 agaaagagca gaaagagcga aaacagcagc catcgccgcc agggtcgatt tgaacatgag
    21181 atttccttaa caaacagagc agaaaaaaag caagtgaaga gattctaaat agccttcaag
    21241 aacaaggcca tccctttacc taattttacg tatctgaaat atatgtaacc tgacgatcac
    21301 tttttattcc gtgatcaaaa tcacctctta aaatgcaatt tagcaaccga ttgcaataaa
    21361 acatttaaac agatcacaaa atcacctaaa atcgcccgct cgcggcatat cccgctatgc
    21421 cattttattt ttgaacgcag gccaatcatg actaacagca atcgcatcaa gctcacatgg
    21481 attagctttc tctcctacgc actgactggt gcgttggtta ttgtcaccgg gatggtgatg
    21541 ggaaatatcg ccgattattt caatctgcct gtttccagta tgagtaacac cttcaccttc
    21601 ctcaacgccg gcattttaat ctctatcttc ctcaacgcct ggctgatgga aatcgtcccg
    21661 ttgaaaacgc agttacgttt tggctttctc ctgatggtgc tggcggttgc cggtttgatg
    21721 ttcagccaca gcctggcgct gttctcggcg gcgatgttca ttctcggggt ggtcagcggc
    21781 atcaccatgt cgattggtac attcctggta acacaaatgt atgaagggcg tcagcgcggt
    21841 tcccgcctgt tatttaccga ctccttcttc agtatggctg ggatgatttt cccaatgatc
    21901 gccgcgtttc tactggcgcg cagcattgag tggtactggg tttatgcctg catcgggctg
    21961 gtgtatgtcg ctatttttat tctgaccttc ggctgtgagt tcccggcgct gggcaaacat
    22021 gcgccaaaaa cggatgctcc ggtagagaaa gaaaagtggg ggatcggcgt actgtttctc
    22081 tctgttgcgg cgctgtgcta catcctcggt cagttaggtt ttatctcctg ggtgcctgag
    22141 tatgccaaag gcctgggcat gagcctgaac gacgcgggca cgctggtgag taacttctgg
    22201 atgtcataca tggtcggcat gtgggcgttc agctttattc ttcgcttctt tgatttgcaa
    22261 cgcattctga ccgtactggc tggtctggct gcgattctga tgtacgtctt taacaccgga
    22321 acaccagcac atatggcgtg gtcaattctc gctctgggct tcttctccag cgcgatctat
    22381 accaccatca tcaccctggg ttcacagcag accaaagtac cgtcgccaaa actggttaac
    22441 tttgtcctga cctgcggaac catcggtact atgttgacct ttgtggttac cggcccgatt
    22501 gttgaacata gcggtccgca ggcggcactg cttacagcaa acggtctgta cgctgtcgtc
    22561 tttgtgatgt gcttcctgtt aggtttcgtc agccgtcacc gtcagcataa caccctgacc
    22621 tctcattaat tgctaatgcc ggacggcact atcgtcgtcc ggccttttcc tctcttcccc
    22681 cgctacgtgc atctatttct ataaacccgt tcattttgtc tattttttgc acaaacatga
    22741 aatatcagac aattccgtga cttaagaaaa tttatacaaa tcagcaatat accccttaag
    22801 gagtatataa aggtgaattt gatttacatc aataagcggg gttgctgaat cgttaaggta
    22861 ggcggtaata gaaaagaaat cgaggcaaaa atgagcaaag tcagactcgc aattatcggt
    22921 aacggtatgg tcggccatcg ctttatcgaa gatcttcttg ataaatctga tgcggccaac
    22981 tttgatatta ccgttttctg tgaagaaccg cgcatcgctt atgaccgcgt acacctctcg
    23041 tcttacttct ctcaccacac cgccgaagag ctgtcgctgg tgcgcgaagg cttctacgag
    23101 aaacacggca tcaaagttct ggtcggcgaa cgcgctatca ccatcaaccg tcaggagaag
    23161 gtgattcact ccagcgccgg gcgtaccgtt ttttatgaca agctgatcat ggcgaccggt
    23221 tcctacccgt ggatcccgcc aatcaaaggt tctgatactg aggactgctt tgtctatcgc
    23281 accattgaag acctcaacgc cattgaatcc tgcgcccgtc gcagcaaacg cggtgccgtt
    23341 gttggtggcg gcctgttagg tctggaagcc gctggcgcgc tgaaaaactt aggtattgaa
    23401 acccacgtta tcgaatttgc ccctatgctg atggcggaac agcttgatca gatgggtggc
    23461 gagcagctgc gtcgcaaaat cgaaagtatg ggcgtgcgcg ttcacaccag caaaaacacc
    23521 cttgagattg tgcaggaagg tgtcgaagcg cgtaaaacca tgcgttttgc cgacggcagc
    23581 gagctggaag ttgactttat cgtcttctct accggtatcc gtccgcgcga taagctggca
    23641 acccagtgtg gtctggacgt tgctccgcgt gggggtattg tcattaatga ttcctgccag
    23701 acttccgatc cggatatcta cgccatcggt gaatgcgcaa gctggaacaa ccgtgtattt
    23761 ggtctggtag caccaggcta caaaatggcg caggtcgccg ttgaccatat tctgggtagc
    23821 gaaaacgcct ttgaaggtgc tgaccttagc gccaagctga aactgctggg cgtagacgta
    23881 ggcggtattg gtgatgcgca cggtcgcacg cctggcgcac gtagctacgt ttacctcgac
    23941 gaaagtaaag agatctacaa acgcctgatt gtcagcgaag acaacaaaac cctgctcggt
    24001 gcggtactgg tgggcgatac cagcgactac ggtaacctgc tgcaactggt gctgaacgct
    24061 atcgaactgc cggaaaaccc ggattccctg atcctgccag cacactctgg tagcggcaag
    24121 ccgtctatcg gtgttgataa actgccggac agcgcgcaaa tctgctcctg cttcgacgtc
    24181 accaaaggtg atctgattgc tgccatcaac aaaggctgcc acaccgttgc ggcgctgaaa
    24241 gctgaaacca aagcgggtac tggctgcggt ggctgtatcc cgctggttac tcaggtactg
    24301 aacgcggaac tggcgaaaca gggcatcgaa gttaacaaca acctgtgcga acactttgct
    24361 tattcgcgtc aggaactgtt ccatttgatc cgcgttgaag gcattaaaac cttcgaagaa
    24421 ctgctggcga aacacggcaa aggctacggt tgtgaagttt gtaaaccgac cgtcggttcg
    24481 ctgctggcct cctgctggaa cgaatacatt ctgaagccgg aacatactcc gctgcaggat
    24541 tctaacgaca acttcctcgc taacatccag aaagacggca cctactcggt gatcccgcgt
    24601 tctccgggcg gtgaaatcac cccggaaggg ctgatggcag tgggtcgtat cgcgcgtgaa
    24661 tttaatctct acaccaaaat caccggctcc cagcgcctgg cgatgtttgg cgcacagaaa
    24721 gacgatctgc cggaaatctg gcgtcagctg attgaagctg gcttcgaaac cggtcatgcc
    24781 tatgcgaaag cactgcgtat ggcgaaaacc tgcgtgggta gcacctggtg ccgctacggt
    24841 gttggcgata gcgtcggcct cggcgtggaa ctggaaaacc gctacaaagg catccgtacg
    24901 ccgcacaaaa tgaagttcgg tgtctccggc tgtacccgtg aatgttcaga agctcagggt
    24961 aaagacgtgg gtattatcgc cactgaaaaa ggctggaacc tgtatgtttg cggtaacggc
    25021 ggcatgaaac cgcgtcatgc ggatctgctg gcagcggata tcgatcgcga aacgctgatc
    25081 aaatatctcg accgcttcat gatgttctac atccgtaccg ccgacaaact gacgcgtacc
    25141 gcgccgtggt tagaaaacct cgaaggcggc atcgattacc tgaaagcggt gatcattgac
    25201 gacaaactgg ggctgaacgc tcatctggaa gaagagatgg cgcgcctgcg tgaagcggta
    25261 gtgtgtgagt ggactgaaac ggtcaataca ccgtccgcgc agactcgctt caaacacttc
    25321 atcaacagcg acaagcgtga cccgaacgtg cagatggtgc cagagcgcga acagcaccgt
    25381 ccggcaacgc cgtatgaacg tatcccggta actctggtgg aggacaacgc atgagccagt
    25441 ggaaagacat ctgcaaaatc gatgacatcc tgcctgaaac cggcgtctgc gcgctgttag
    25501 gtgacgagca ggtagcaatt ttccgcccgt atcacagcga tcaggtgttt gcgatcagca
    25561 acatcgaccc gttcttcgag tccagcgtgc tgtcacgcgg gctgattgcg gaacaccagg
    25621 gcgagctgtg ggtcgccagc ccgctgaaaa aacagcgttt tcgcttaagt gatggcttgt
    25681 gcatggaaga cgaacagttt tccgtcaaac attacgaagc acgagtgaaa gacggcgtgg
    25741 tgcagcttcg cggttaatgt tttaacggga ggcgcaatgc ctcccctttt tgcatggtcc
    25801 tgtaatgacc ttcggtatat tgcaggacat tttttaaact ttttgtttta tttttttgtt
    25861 tttatttttt aaaggataat caaatgttta cagacactat taataagtgt gcggctaacg
    25921 ctgcgcgcat tgcacgcctg tcggcaaata acccgctcgg cttttgggtc agctccgcca
    25981 tggcgggcgc gtatgtgggt cttgggatca tcttgatttt cacgctcggt aatttgctcg
    26041 acccgtccgt acgtccgctg gtgatgggcg cgacctttgg tatcgcctta acgctggtga
    26101 ttatcgccgg ttctgaactg ttcaccggac acaccatgtt cctcaccttt ggggtaaaag
    26161 cgggcagcat cagccacggg caaatgtggg caatcctgcc gcaaacctgg ctgggtaacc
    26221 tggtcggttc cgtcttcgtt gccatgctct atagctgggg cggcggtagc ctgctgccgg
    26281 tagataccag catcgttcac tccgtcgcgc tggctaaaac cactgcaccg gcaatggtac
    26341 tgttcttcaa aggtgcattg tgtaactggc tggtttgcct ggcaatctgg atggcgctgc
    26401 gcactgaagg ggcggcgaaa tttatcgcta tctggtggtg tctgctggca tttatcgcgt
    26461 ctggctacga gcactctatc gctaacatga cgctgttcgc gctctcctgg ttcggcaacc
    26521 acagcgaagc ctacacgctg gcgggtattg gtcataacct gctgtgggtg acgctgggta
    26581 atactttatc aggtgccgta ttcatgggat tgggttattg gtatgctacg ccgaaagcga
    26641 atcgtccggt tgcggacaaa tttaatcaaa ctgaaacggc tgccggttaa ttactaaggg
    26701 gtttttacgt ggatcatttg cctatatttt gccaattacg cgatcgcgac tgtctgattg
    26761 tcggcggtgg tgatgtcgcg gaacgcaaag caaggttgct gttagacgca ggcgctcgct
    26821 taacggtgaa tgcattagcg tttattccac agttcaccgc atgggcagat gcaggcatgt
    26881 taaccctcgt cgaagggcca tttgatgaaa gccttctcga cacctgctgg ctggcgattg
    26941 cagcgacgga tgatgacgcg cttaaccagc gcgtcagcga agccgctgaa gctcgtcgca
    27001 tcttctgtaa cgtggtcgat gcgccgaaag ccgccagctt tattatgccg tcgattattg
    27061 accgctcacc gctcatggta gcggtctcct ctggcggcac ctctccggtt ctggcacgcc
    27121 tgttgcgcga aaaacttgaa tcactgctgc cgttgcatct gggccaggta gcgaaatacg
    27181 ccgggcaatt acgcgggcga gtgaaacaac agttcgccac gatgggtgag cgtcgccgtt
    27241 tctgggagaa attgttcgtt aacgatcgcc tggcgcagtc gctggcaaac aacgatcaga
    27301 aagccattac tgaaaccacc gaacagttaa tcaacgaacc gcttgaccat cgcggtgaag
    27361 tggtgctggt tggtgcaggt ccgggcgatg ccgggctgct gacgctgaaa ggactgcaac
    27421 aaattcagca ggcagatgtg gtggtctacg accgtctggt ttctgacgat attatgaatc
    27481 tggtacgccg cgatgctgat cgcgttttcg tcggcaaacg cgcgggatac cactgtgtac
    27541 cgcaggaaga gattaaccag atcctgctgc gggaagcgca aaaaggcaaa cgcgtggtgc
    27601 ggctgaaagg tggcgatccg tttatttttg gccgtggtgg cgaagagctg gaaacactgt
    27661 gcaacgcggg tattccgttc tcggtggttc cgggtattac cgcagcttct ggttgctctg
    27721 cctattcggg tattccactc acgcatcgcg attatgccca gagcgtacgc ttaattaccg
    27781 gacacttaaa aaccggtggc gagctggact gggaaaacct ggcggcagaa aaacagacgc
    27841 tggtgttcta tatggggttg aatcaggccg cgactattca gcaaaagctg attgaacacg
    27901 gtatgcctgg cgaaatgccg gtggcaattg tcgaaaacgg aacggcagtc acgcagcgcg
    27961 tgattgacgg tacgctcacg caactcggtg aacttgctca gcaaatgaac agtccatcgc
    28021 taattattat tggtcgggtt gttggcctgc gcgataaact gaactggttc tccaaccatt
    28081 aatttaaccc gggccagaga attctggcct tcttaatgac tctttttata tattcagcaa
    28141 ataaaacata accccttaat aaatattatc tgctaatggg ttatattcac cgttacagcg
    28201 acttacaaaa ttaagtcatt cgctcactga cgccaattaa atattcctgt atcgttctta
    28261 acgagcagtc tgcttatatt catataatca atgaatatta attaatatat aatacatagg
    28321 gaatgtaaat gaacaaattt attaaagttg cactggtagg tgcagtactg gctacgttaa
    28381 ctgcatgtac tggtcatatt gaaaaccgtg ataagaactg ctcttacgac tacctgctgc
    28441 acccggcaat ttctatttct aaaatcattg gcggttgcgg tcctactgca cagtaagtct
    28501 ctgacagaaa tcggctaaca ccggtttaat tgcccgacgc cctctggatt ttccgagggc
    28561 gtatttgttt ctatatcctt cttgcccccg cccgtaaaaa tattttcact ttaaattcaa
    28621 tttgataact acatccatta gccacagcgc gatcctgtgc gaaattttgt gatcttcctc
    28681 cacattacat aacatcatat gttgttatat tcatcatgca ttgtcatgtt accttttaaa
    28741 tgactgcaaa ctctccccta caacgtattg gacaagaaaa aggtatcgct atgggaagcc
    28801 aggaactcca acgcaagctc ggattttggg ccgttcttgc aatcgccgtc gggacaaccg
    28861 tcggctccgg tatttttgta tctgtgggtg aagtggcaaa agcagcgggc acgccgtggc
    28921 ttacggtgct cgcgtttgtc attggcgggt taattgtgat cccgcaaatg tgcgtctatg
    28981 cggaactatc caccgcttat ccggaaaatg gcgcagatta tgtttatctg aaaaatgccg
    29041 gaagccgacc gctggctttc ctctccggct gggccagctt ctgggccaac gatgcgccgt
    29101 cattgtcgat tatggcgctg gcgattgtca gcaatcttgg ctttttaacg cctatcgatc
    29161 cgttgctcgg taaatttatc gccgccggat taattatcgc ctttatgttg ctacacctgc
    29221 gctccgttga aggcggcgca gcgtttcaga cgctaattac catcgccaaa attatcccgt
    29281 tcactatcgt cattggcctt gggatcttct ggtttaaagc ggagaatttt gccgccccta
    29341 ccaccactgc gattggcgca acgggcagct ttatggcgct gctggcgggg atctctgcca
    29401 ccagttggtc gtataccggc atggcctcta tctgttatat gaccggcgaa attaaaaacc
    29461 ccggaaaaac catgccacga gcgctgattg gttcctgtct gctggttctg gtgctctaca
    29521 ccctgctggc gctggtgatt tccggcctga tgcccttcga caaactcgcc aattctgaaa
    29581 cgccgatttc cgacgccctg acctggatcc ccgcactcgg cagcaccgct gggatctttg
    29641 ttgccatcac ggcgatgatc gtcattcttg gttcgctttc cagctgcgtg atgtaccagc
    29701 cgcggctgga atacgcgatg gcgaaagaca acctgttctt taaatgcttc ggccatgtgc
    29761 atccgaaata caacacgccg gatgtctcca tcatcctgca aggggcgcag gggatcttct
    29821 tcatcttcgt ttccgatctc accagcctgc tgggttattt caccctggtg atgtgtttca
    29881 aaaataccct caccttcggc tccatcatct ggtgtcgtaa acgcgacgat tacaaaccgc
    29941 tgtggcgtac tccggctttc gggctgatga ccaccctcgc cattgcgtca agcctcattc
    30001 tggtcgcctc aacctttgtc tgggcaccga ttcccggcct tatctgcgcc gtcatcgtta
    30061 ttgctactgg tctgcctgct tacgccttct gggcgaagcg tagccgccag ctcaacgctt
    30121 tgtcgtaatg ttatctggag aaaataaaat gttggatatt gataaaagca ccgtggactt
    30181 tctggtcacc gaaaatatgg ttcaggaagt ggaaaaagtt ctcagccatg acgttccgct
    30241 ggtgcacacc atcgtggaag agatggtgaa gcgcgacatt gatcgtattt atttcgttgc
    30301 ctgcggatcg ccactcaacg cggcgcaaac ggcgaaacat ctggcggatc gcttttccga
    30361 tcttcaggtc tacgccattt ccggctggga gttctgcgat aacaccccgt atcgcctcga
    30421 cgatcgttgc gcggtgattg gcgtttctga ctacggtaaa acggaagagg taatcaaagc
    30481 gctggagctg ggccgggcct gcggcgcact cactgcggcg ttcaccaaac gcgcggacag
    30541 cccgattacc tcggcggcgg aatttagcat tgattatcag gccgactgta tctgggaaat
    30601 tcacctgctg ctctgctaca gcgtggtgct ggagatgatc acccgcctcg cgccgaacgc
    30661 ggaaatcggc aagatcaaaa acgatctcaa gcagttgccg aatgcgctcg gtcatctggt
    30721 acgcacctgg gaagaaaaag gccgccagca tggtgaactg gccagccagt ggccgatgat
    30781 ttataccgtt gctgcgggtc cgctgcgtcc gctgggttac aaagaaggca ttgtaacgct
    30841 gatggaattt acctggacgc acggctgcgt gattgagagc ggagagttcc gccatggccc
    30901 gctggagatt gtcgaaccgg gcgttccgtt cctgttcctg ctcggcaatg atgaaagtcg
    30961 ccacaccacc gaacgcgcca ttaactttgt taaacagcgt actgacaacg tgatcgtcat
    31021 cgattacgcc gaaatttcgc aagggctgca cccgtggctg gcaccgttcc tgatgttcgt
    31081 gccaatggag tggctctgct actacctgtc tatttacaaa gatcacaacc cggatgaacg
    31141 ccgctattac ggtggtctgg tggaatatta atccctctcc cggcccggca acgggccgaa
    31201 tttacgcaag gagttacccg atgaaaacag gtatgtttac ctgcggccac cagcggctgc
    31261 ctattgaaca cgcatttcgt gatgcaagcg agctgggtta cgacggcatc gaaatttggg
    31321 gcggtcgccc gcacgcgttc gcgccggact taaaagcggg cggcatcaaa caaatcaagg
    31381 cgctggcgca gacgtatcag atgccgatta tcggctatac gccagaaacc aacggctatc
    31441 cgtataacat gatgctgggc gatgaacata tgcgtcgcga aagcctcgac atgatcaagc
    31501 tggcgatgga tatggcaaaa gagatgaacg cgggttatac gctgatttcc gcggcccacg
    31561 cgggctatct cacgccacct aatgttatct ggggacggct ggcagagaac ctaagcgaac
    31621 tgtgtgagta cgcggaaaac atcggcatgg atctgatcct cgaaccgtta acgccgtatg
    31681 aatcgaacgt cgtgtgtaat gctaatgatg tgcttcatgc gctggcgctg gtgccttcgc
    31741 cgcgcctgtt cagcatggtc gacatttgcg cgccgtatgt ccaggcggaa ccggtgatga
    31801 gttatttcga caaactgggt gataaattgc gtcatctgca tattgtcgac agcgacgggg
    31861 ccagtgacac acattacatt cccggcgaag gcaaaatgcc gctgcgggag ctgatgcgcg
    31921 atattatcga ccggggctat gacggttact gcacggtgga actggtgacg atgtatatga
    31981 acgagcccag actctatgcc cgccaggcgc tggaacgctt tcgcgcgctg ctgccggagg
    32041 atgagagatg aaaaccctgg cgacaatcgg cgataactgc gtcgatatct acccgcaact
    32101 gaataaagcg ttttctggcg gtaatgcggt caatgtggcg gtgtactgca ctcgctacgg
    32161 catacagccg ggacccatta cctgggtggg tgacgatgac tacggcacaa agctgaagca
    32221 ggatctcgcc cgcatgggcg tcgatatcag ccatgtccat acgaaacacg gcgttaccgc
    32281 acaaactcag gtggaactgc acgacaatga tcgcgttttt ggcgactaca ccgaaggcgt
    32341 gatggccgac tttgccctga gtgaagagga ttacgcctgg ctggcgcagt atgacattgt
    32401 gcacgcggca atctggggac atgcggaaga cgcattccca cagctgcacg ctgcgggcaa
    32461 acttaccgct ttcgacttct ccgacaagtg ggacagcccg ctctggcaga cactggtgcc
    32521 gcatctcgat tttgcctttg cctccgcacc gcaagaagac gaagcgctgc gtctgaagat
    32581 gaaagcgatt gttgcccgtg gcgcaggaac agtgattgtc acgctgggtg aaaacggcag
    32641 cattgcctgg gatggcgcgc agttctggcg tcaggctcct gaaccggtga cggttatcga
    32701 caccatgggt gccggagatt cgttcattgc cggattcctt tgcggctggt ctgcggggat
    32761 gacattaccg caggcgatgg cgcagggaac ggcgtgcgcg gcgaaaacca ttcagtacca
    32821 cggtgcctgg taggtataac gttggcgtga gcatcttcac gccaacgtgc tgttacttgc
    32881 cggaaaacga ccctataatc cgagtaattc attctttatt tcagggtcga ttatgtcagc
    32941 tacggaccgc tactctcatc aactcctcta cgctaccgtc cgccagcgac tgctggatga
    33001 tatcgcgcag ggggtttacc aggccgggca acagatccct accgaaaacg agctttgtac
    33061 acaatataac gtcagccgca ttaccattcg caaagccatc agcgacttag tggcagacgg
    33121 cgtactgatc cgctggcagg gaaaaggcac ctttgtacaa agccagaaag ttgaaaacgc
    33181 cctgcttact gtcagtggtt ttaccgattt tggcgtctca caaggcaagg cgacgaaaga
    33241 gaaagtgatc gaacaggaac gggtcagcgc cgcgccgttt tgcgaaaagc tgaacatccc
    33301 cggaaacagc gaagtgttcc atctctgccg ggtgatgtat ctcgataaag agccgctgtt
    33361 tattgatagt tcatggatcc cgctgtcgcg ttatcctgac tttgatgaga tttacgtcga
    33421 aggaagctcc acctatcagt tatttcagga gcgttttgac acgcgagtgg tcagcgacaa
    33481 aaagaccatc gatatctttg ccgccacccg cccgcaggca aaatggctga aatgcgaact
    33541 gggcgaaccg ttgtttcgca tcagcaaaat cgcctttgat cagaatgaca aaccggtgca
    33601 cgtctccgaa ctcttctgcc gcgccaatcg catcacctta actattgata ataaaagaca
    33661 ttaaccgtag gccggataag atgcgccagc atcgcatccg gcgatgctgg cgcgttgaat
    33721 tttacatccc gtacgttcct ctcaccctaa ccctctcccc aaaggggcga ggggaccgtt
    33781 cagtacggaa tttagcttga cggtgctatc cagcattaaa tactggcaat actctcacgc
    33841 aaaatccgca gcaccgtctc ttcaccgctg cgattcgggt taatgcgaat cgcacaatgt
    33901 tctgattgtg gattcgcctg gcgaaacgtt ccggaaaggc gataaaagag cggcgggatt
    33961 tcatatttcg actctgcacc caccgggtaa ggcaaggcac cgcgcttttg cgcctcttcc
    34021 agcactctgg cggcaatcgg ctgatgaaac tcgacaatca acaccttcga ctgcgcatta
    34081 gcaatcaccg cgcttttcac ttccggcacc gcaccaccgt taagcaaagc cagcaaccgt
    34141 tcagataccc ctgcctgcac cgcgtgcatc actggcgcaa acaccagacc acgcaagact
    34201 tccagcgcct gtgcgccctg gatctggcta ccgccggagt aaagcgtggc gcgaatacgg
    34261 ttgataacat cagcatcgcc gaccactgca ccaacaccct ctggcccaaa tagcttgaag
    34321 caggaaaatg tcgagatatt cgcgccgcat tcacagccga ttcgcgccac cttcatcacc
    34381 gcatagttgt catcggttaa cgctggaaca cctgccgcgc gcaacgttgc cagcacatct
    34441 gccagcacgt agctgtcctg cggctgctgg cgcgtatgct gcaccagcgc cgcatccggt
    34501 tgttgctcgt cgacgacctg cttcagtgcc gacaggtcat tgaaatcaac agtaataagc
    34561 gtcagcccca tctgctcaat aataacccgt gtcgtcgggt aaacaggcgc gtcatgcacc
    34621 agaagacgct gccccggttt gagcaaagcc gccagcccgg cgcgaatcgc gccagtcccc
    34681 gcgccctgca ccagcgccgc agcctgtgcg tgaaatgcat cagccagcac ctgttccaca
    34741 cgctgggtaa cgcgcggttg attcagtcct ggcgttaagc ctaaatcacc gccagtaaga
    34801 aactcgctgc cggggaaatg gcgacaaatg ctatccacca gcgcaaactg cttttgctgc
    34861 gcctcaataa tcgtcaggct ttgcagagga aacgtcttca taggtgcctt ccttaagccg
    34921 gaacgaacag gccaagccag taaagaacat tcagcagaat accggtgatc attactgcca
    34981 cgaccggtgc cgccattttc tgtaccggac ggcccaggga ttcgttgagg aagtaaatgg
    35041 caaccgcgat agagaatccg gtataacccg ccatcttaat tgctgcgaaa atcgaaccga
    35101 ccagcagcgc cacttccatc agcatattca tggcgttacg gatgttatcc gacgcattac
    35161 gcaccgacgg gtagcgtccc agccatttgc cgatcgaacg aagcagcaag acttccgccg
    35221 aaataaccac tgcgcctaat accgctgcaa ccatcggatt cggcgagaga tagcccaccg
    35281 cataaacaaa ggtaaagccc gcaactgcat acacacccgt tgctaaggcg gtggtggcaa
    35341 tcaacggtac aaaacccagc ccgcgcataa attctgccag tgccgcctgg ttgatcagcg
    35401 tttgcgattg ttccggcgtt acgcctgcgg agtacgcttt ctccagagtg aagatcgaca
    35461 cttcactgcc ggcgaaaatc ttcatgctgg caacggcggc aatcaatgct cccacgatgg
    35521 cgatataggg taagtttttg ataatccgcg acgtgcgttc ttcaaacacc gaaagcccgc
    35581 tggcatcaat atcattttca tcacgatgac gcaggtcgtg agttatcgcg atccccagca
    35641 gcatcaccat gccaataaag atttcgatgg attcagggtt aagatgtggg aaatagcgca
    35701 cgactaccac acgggtcatc agaacaacca cggcggcgac cagactttgc ttccagccaa
    35761 actggtagaa aatcgccacc agcgggaaca gtgcaaaagc agaaaccacc ggcgagctta
    35821 attccccgag gctacctaat acatccaccg gcagcgcggt cagcagctgg tttactggca
    35881 acaggcaagt aaggatcaat acgccccaga tagcgccaag accaaacgcc atcaggctgt
    35941 ttatcgccag tacgccgagg atatcggtag gaagaaagag taaccatgcg ttgagcagtc
    36001 cggttttcag ggtaaaagag atccccaccg aggccacaaa accaatgctc agaccaaaag
    36061 cgatactccc cgcctcgcga cggttcatat agccttcaat cagttgcggc aggatcgggc
    36121 ggatgccgtc atgaaaaaca gccgccgagc gatgcgccag aagcgatgtc atacccgtca
    36181 ggcacgccac cacgataatc tgaatataca gatccatagt cgtgcctttt atttcagatg
    36241 gttaatcagc atcggaatcg cgtgttcgac gtgctcaacg gaaaggccaa acgccacttt
    36301 tccttcagcg atcattttgg cgatatgctc gtctttcgct ttaatgcctg gtttggcaat
    36361 ggtgcaactt ttgttatagc caatcaccgc gatggcaatc gacaatgccg cgcccgcacc
    36421 ggtattacac gcaccgatgt agtaatccag ttgcccggat ttcactttca ttgccgcttc
    36481 catgtcgttg tgaatgaaaa cttcaaaact gccaggagcc gtcgcttcaa tggttttttt
    36541 aatctgctca cgctgtaagc ctgcaacgcc aatctttttc atgagtctgt ccttattgga
    36601 aaaattgaga gggagtttca cgtaacatca catccacatc ggcctgactg aatcctgact
    36661 ggcgcaattg cggaataaag gtggtcaata aatagtcata gccataacca ccattggctt
    36721 ttaaatggga gcggcgcgta atatccatcg acagcatgac gcggttcagc aacccacggt
    36781 cacgtagcgc gtggagcatc gcaatgcgct tttcgtccgg gtagtaactg ttcttaccaa
    36841 tggtgtcgaa ctgcacgtac gcgccgagat cgatcatctt caaaatgttg tcgaggttgt
    36901 ctttcagatc gcagtgacca acggtgacgc gcgaaagatc aactccgtgg gcttgcaaca
    36961 gagccagttg ttccagcccc atggtgctga acgaagtatg cgtggagatc gggcgtccgg
    37021 tctggttatg cgccagcgca gcggcaataa acaccttctc ttccagcggc gtaatcttcc
    37081 cttcgctaga gccgatctcc gcgataatcc cggctttcag gtcggtgcca tcgataccct
    37141 gttcaatttc atcgaccatc tcctgcgcca gttcctgcac gctgcgggtc gccacatgct
    37201 ccgggaaaaa agcgtcctgg taataaccgg tgcaggccac cacgttgatc cccgtctcgc
    37261 gcattacatc gagcataaat tgcgcattgc gccccatgta acggttggtc atctcaatca
    37321 cattacgcac gccccgggtc atcaggtcgt tcatctcctg gcaaatgaac gcatactgat
    37381 caaggcggca gtccacgttg tttttaaagc cggagagatc aatatgcaga tgctcatggg
    37441 ccagggtgta acccgtcgga tcaaaactca tagggtgtct cctgcaaacc ggagggagga
    37501 aagaaaagag cgaccatttt gtggcggtgg cgcacggaaa aattcacaca cggtagcccc
    37561 cacatctgaa agcgtggtgc gcacaccgag ctgcgtagct atcatccctt gctgataaac
    37621 cagcactggc accacttcgc gggtatggtg gctgtgacca atggtcggat cgttaccgtg
    37681 atccgccatc acgaccaggc aatcatctgg ctgcatcgcc tcaacaagcc gggcaaggtt
    37741 acggtcaacg acctgcaaac gttcggcata acgtgcgacg tcttctgcat gaccagcgag
    37801 gtcggtttcc tggatattgg tgcaaataaa cgccgtcgga tgcgtgttaa attcgtcaag
    37861 ggtgatatcc ataatccgct ggctatccac caggttttgc cagctcacgc cataaggatt
    37921 gctgacgata tctgccactt tacctaccag cacggttggc acgcccgcct catacagttt
    37981 ttgcggcacc tgcacttttt catcaacacc gtagcccata tgcacgacct ggaaaccgtt
    38041 gtcataagcg ccagaacgcg gcgcattgat gccaataaag cgcccttctt tgctttctgc
    38101 ggcatcgaga atacgctgac tgtcggttaa caagccgcca aatgtaatga cccgaccgac
    38161 ctgtacctgc tcacgcacga tacgaccaat tttgattgcg tcgtcaaaag agatcacaga
    38221 gagattggcg gtaatgttat agacttggcc taaatccgcc tcgagattat cgccaatcgc
    38281 aaccgcctga ttgacccaca gaaattgcag atcatcgcca cggcgctcca cctgccagcc
    38341 agcggaaact aatgcctgct caacacggtc aatcacatcg cgaaaaggca tccgcagcgg
    38401 cggtaacggg cgcgtgccta aaatttcctg atgccccata aaggtatcgc caccttcatg
    38461 ttgcagctct gccacgcccc aggttgcgga atctgacggc tgcatatcgc ctggcgcata
    38521 acccaatgcg ttgattagcc ccagcttctc cagcgttggt agctgcaaat gcggcaactg
    38581 gctcaggatg tgaccacagg tattcgctcc cgcatcttgc ggacgcacca gcgtgacatc
    38641 tttcattgcc cctacgccaa agctatcaat cactaacacc acaaatcgcg ccattacgcc
    38701 cccagagagt ttccaagact gtcataacga ccaacgattt tcggttcgcc acggtgaata
    38761 ccggacacca gcaccacatc gctacgggtg acaaaaatct gcgtgcggaa acagagcacc
    38821 actgcactgc ttaccggaaa ctcgcctgcc agcgacaggg tgtagtcgat actgctgtca
    38881 tccacagttt tgagattggt ttcagtaatc ttttgatttt ctggcgtaaa caccaacgca
    38941 tgttgcgcat gaccacgacg gtagtaaccg ccgccgtagc agtagctgtc gccacggaaa
    39001 tgatgggaga tttcactcaa ccagagcatc gcgatacgtt cagactgatc gccctgctgg
    39061 tttgccggaa tagtgcccgt cagcgcatga ccgggttcgg catgagtcac accgtattgc
    39121 gccagtaatg gcagcgaagt gcagctggtc gctgaaggcg cgttcagttg ctcaatcaca
    39181 ataccagatt tcgccagttg atcccgtgct tgtaccagcg tgtgaagatt cggtgtcggc
    39241 aaaactttcc cggcagcctc atcccaaagc aggcaaggga aatgggtaag tccggctaaa
    39301 tgcagccccg gcagtttctt aatttcagca accacctcgt gcagcgaatg ctgtacaaaa
    39361 ccgctctcct gccccggata aagaaaatca tcgtcgctat aaactttgag cagcacagac
    39421 tggattcgcc cggccttcac cgccgccgca gaaacttccc gcgctttgtc gagagtaaac
    39481 acggtgatga cgtcggtgcc ctgttcaacg gcgtcagcaa cctgatgaca agggatttgt
    39541 accagatgcc cctgatgcgc caccggcaaa ccagcgcggc gcatgactcg cgcctctttg
    39601 taatccaccg ccacaatgcc gctgtagccc aacgccagca gtttttccgc cagccatggg
    39661 ttacgaccga attgtttggt catcagatac agttcaatgc cgtaaagccg cgccgtctca
    39721 atcagccgct taccgttttc cagtatctga tccacgtcga tcacccagct gtccggggcg
    39781 attttgccct gctgccacaa acttagtgcg gcggaaatca gcgccgggtt ctggcgtttc
    39841 aatgcttcta caaacatctt gttgcctcgt ttctgttcct tgaattaaat attcattttt
    39901 ttgaatattt aggttgtgcg acgtggattt gtcgggagct tcaaacctct tcgttagcag
    39961 ccatccataa tccataaagg ttggccagca aatagccttc ttcacacggg ttaacttcca
    40021 gtgcgaattc cttcaacaat acctgatgca attgcacaac agcttgccag tggctggatt
    40081 gcgccagctc tgccagcaat tcgttatcca gcggctctat ttcttcacca cggcgactgc
    40141 gcatcagtgc actcgccata tgtgtaatcg ccatcgttcc ttgctcactg cgcactggca
    40201 gatggcactc tgtttccagt acgttgacga cctgcatcat gcctttgcag atgtccttat
    40261 caataacgcc tgcctcgcaa agcaggttga gtctggtttc catatcagat gcctttcgtt
    40321 taataactcg gttcctgttc cccactcacc acgcgttgtt gatgggcgag cagggcgtgt
    40381 ttatctacaa cggcacgcag cagttgttgc attgggtaat catcggctcg cgtcaggacc
    40441 acggcttcgg tggcctgtaa aaatcgcgga tcgtctgtga gcggcgtcgc ctctaatccc
    40501 agcatggtca gttcgttttc cgccaccacg ttccagataa ccgcatcgac atcgccttta
    40561 acaatgcgtt gtaaactctc gtgataagag agatcgacac gttccacatc actatcgcca
    40621 aaaaagacat cggtcatgat tttctgatcc gccgaacggt tatccagccc cacgcgcttc
    40681 acgtttgcgg actcgccttt acggcaaatc aactggtgct cgccaacgta ggtgtgcggc
    40741 cccaactcca gcgcgaggca aaaccctttt tgcgtgagat aactttccgc cgccagtcgg
    40801 gaaaccaccg ccatgtcata cacgccgtta agtaaacact ccacgcgaat atccgcgccg
    40861 cgcatatgcg catagtaaaa aggaatgcca tcaaactggg ctttcaatcc gctcgctaaa
    40921 ccttcgtaca agcgggtata gggcaaaggc atcgcacata ccacgttgtt gatatccaca
    40981 tgactcagca atgctttgtt atccatctcg accagataac tgccattgcg cccacggcgt
    41041 tcaatccgta tcgctccgct tgattccagc gttttcaacg cggcctgcgt caggccaacg
    41101 gatgaacggc attcagttgc cagctcatct atggttttca acctattacc gcatttttca
    41161 cccaacaaat aacgggccag cgtcgtgata acgacgcctt cttttttgat aaacgttcga
    41221 cgcataatat attttcaata aaatgaatgt ttatatcttc attaaaatga agataagtgg
    41281 caactgtgag atgtggaaac ggcgaggcgc ttcacatttt ttcggattat tgcaaatgag
    41341 gataaaaaaa ccgggtttcc ccggtttcag agtgatgacg aagtgattta ttcgacaatg
    41401 cgagcaaagg gtaattccca ctggcgcttg cctgctcccc tcaccctaac cctctcccca
    41461 aaggggcgag gggaccgtcc gagcgttttg atattacggc ttcgccacaa aaccaatcgc
    41521 ttcgtacacc gctttcagcg tacgggaagc gtgtacactg gctttttctg cgccgtcttt
    41581 catcacctgt tgcaggaagg cttcatcgtt gcggaaacgg tgatagcgtt cctgcaattc
    41641 agtcagcata ccggaaacgg catcagccac ttcacctttc agatgaccat acatcttgcc
    41701 ttcgaactgt ttttccagtt ctggaatgct ctggcccgtt accgcagaaa ggatatccag
    41761 caggttggaa acgcccgctt tgttctgcac atcgtagcga actaccggcg gctcgtcgga
    41821 gtcagtgacc gcgcgtttga ttttcttcac taccgatttc ggatcttcca gcaggccgat
    41881 aacgttattg cggttatcgt cagacttgga catcttcttg gtcggctcca gcagcgacat
    41941 tacgcgcgcg ccagatttcg gaataaacgg ctccggcacc ttaaagatct cgccatacag
    42001 cgcgttgaaa cgctgggcga tatcgcgact cagttccagg tgctgtttct ggtcttcacc
    42061 caccggtacc agattagttt gatacagcag gatgtccgca gccatcagca ccggatagtc
    42121 aaacagacca gcgttgatgt tctcggcata acgcgcagat ttatctttaa actgggtcat
    42181 gcggctcagt tcgccgaagt aggtatagca gttcagtgcc cagcctaact gcgcatgttc
    42241 tggtacgtgg gactgaacaa aaatggtgct tttctcagga tcgataccac aagccagata
    42301 caaggccagc gtatccagcg tcgctttacg cagcttctgt gcatcctggc gcacggtgat
    42361 cgcgtgttgg tcaacgatac agtaaatgca atggtagtca tcctgcatgt ttacccactg
    42421 acgcagcgca cccatgtagt taccaatggt caattcacct gagggctgtg cgccactaaa
    42481 aacgatgggc ttagtcattt ttcgattcct gattttcgct atgcggaagc cctaatgcgg
    42541 gcagaaggtc atttatagac tgataaatta catcaggctg gctgagatcg atagcctcgc
    42601 cgtagttata tccgtaggtt aagccaactg atgggcaacc tgccgctttt gccgcctgaa
    42661 tatcattgcg tgagtcgccg acaaacagca tctgttgtgg ggcaattccc atccgctcag
    42721 ccaccagtaa cagcgggtcc ggatgcggtt ttttgttttg cacatcatcg ccgccgataa
    42781 ccacgctaaa gtatttggca atatctaagg cttcgagcag cggcgcgacg aacggcgtcg
    42841 gtttgttggt gaccaggcct agcggcaggc ctttagcctg caacgcgccc aacgtatcgg
    42901 caacgtgcgg gaacaaaaac gtcccctctt cggcaacctc gccatagtag cgatcgaaca
    42961 gtttacgcag aatacgtacc tgttcttctg ccggaatgtc gtcatcaacg ggcggtttac
    43021 ccattgtttt acgctgagtc gcacgttcct gacgcgccca ggtcaatgcg cgctccatca
    43081 gaacatctgc gccgttacca atccaggtaa taacgcgttc ttcacctgcg acgggcaact
    43141 ccagcgcata cagcgccata tctaccgcag cagcaagacc gggagcactg tcgaccagcg
    43201 taccatcaag atcaaaagcg acgccgcgaa tatcttcaaa cttattcatg acttaccttt
    43261 gccagttcac tgcgcatttc atcaatgact tttttgtagt ctggctggtc gaagattgcc
    43321 gaaccggcga cgaacatatc cgcgcccgcc gcagcgattt cgccaatgtt gttcaccttc
    43381 acgccaccgt ctacttccag acgaatgtca aagccagact cgtcgatacg acgacgtact
    43441 tcgcgcagtt tatccagtgt ttgaggaatg aacgactgac cgccgaaacc aggattgacg
    43501 gacatcagca ggatcacatc cagcttatcc atcacgtaat ccagatagct cagcggtgtc
    43561 gccgggttaa ataccagtcc cgctttacag ccattttctt taatcagttg cagcgtgcgg
    43621 tcaacatgct cggaggcttc tggatgaaag gtaatgatgc tggcaccagc ggcagcgaaa
    43681 tcaggcacaa tgcgatcgac aggtttcacc atcaggtgta cgtcgatagg ggcggtaatg
    43741 ccatagttac gcaaggattt cagcaccatt ggcccaatcg tcagattggg aacatagtgg
    43801 ttatccatga cgtcaaaatg cacgacatca gcgccagctg ccagggcttt tgcggtatct
    43861 tcacccaggc gggcaaaatc agccgacaga attgaggggg caatcaaata ctgtttcatc
    43921 cgcttctcct tgagaattat tttttcgcgg gtgaaacgac tcctggtttg tacaaagcca
    43981 gcagttcgtc caccttttta cgtgtgccgc cgttgctgct tatactgcgt cgaactttga
    44041 cgacatgcaa ttttgcgcgc tgataccact cacgcgttaa catcgtatcg tgattggaga
    44101 tcagcactgg aatatggcgc tcaaccagac cttcggcgat ctccgccaga tgcgcttgtt
    44161 gttcaagcgt aaaactgttt gtgtgatacg ccgtaaagtt ggcggtcgca gacagcggtg
    44221 cataaggcgg atcgcaatag acgacggatg catcatctgc gcgcgccatg ctatcggcgt
    44281 aagactcaca atagaaaaag gcattctgcg ctttttcagc gaagtgatac aactctgctt
    44341 ccgggaaata gggttttttg tagcggccaa acggcacatt aaactcaccg cgcagattgt
    44401 aacgacacag gccgttgtaa ccgtagcggt tcaaatataa aaacagtacc gcccgacgga
    44461 acggatcctg gcttttgttg aactcttcgc ggaactgata gtaaacctcg gcgcaatttg
    44521 tttcgggaac aaacagctcg cgtgcggcct gtacgtactc atcagtacgc atcttcacaa
    44581 tgttatagag actgatcagg tcgctattga tatcggcaag gatataacga gaaaagtcgg
    44641 tgttgagaaa caccgacccg gcacctacaa aaggctcaac cagacattcg cccttgggca
    44701 aatgccgttt aatatcatca agcaggggat acttgccccc tgcccacttc aaaaaagcgc
    44761 gatttttctt catgctgact aactaattac accttctccg gctgtggaga aagctccgac
    44821 agcatccagc gcttcaggca actcccgcaa cgataaacca ttgcgggaga taaccttgat
    44881 tacttcagat cggcctgtac ctgacgcagc ggtttcgccc acgggttttt ggcctggaca
    44941 tctgctggca atgtagatac cgcttttttc gcctcttctt tcgaagcgta cacgccagaa
    45001 accaggacat accacggctg accattacgc gtcgtttcat agacaacgta gtttttcaga
    45061 ttctctttct tcgcccaacc gttcaggttg ccgtagttag aggaactgct cagctgcaga
    45121 gtgtaatggc tggacggtgc cgatttcaac gaaccaacat tacctgcggt cttccctcca
    45181 gcggctggtg ttgccgtggt ttgcgccggg gatgccgtct gtactggagc cgtagtcgcc
    45241 gtctcttttg ttgctggcgt agaagtcgca gccggtgcct tcgtgctcgc cacaggggca
    45301 gctggttcag tacgcttcgg cgtctgtgct accggcttcg gctccgtttt cacggttgct
    45361 tgcggttttt tcggttcaat cactgcctgc tggcgagctg gacgcgtagt ggccggacgt
    45421 tcagcggttt gcgttttcgc cgtttcacgg gatgcattgc cattgcgaac aggcgcgaca
    45481 gtcgcgggtt cggtcggcaa tgtggaattg accgccacat tgttcaactg ttgctgattt
    45541 tgtggttggg tcagcgcatt gttcaggtca ccctgcactt caacacgttg ttgaccatcc
    45601 gttgccgccg gggtttgccc ttgagtcggc gtagaagaga tcggcggcag agaaacatcc
    45661 tgctgagtat tttccgcaga cgtggttccc ggcgctggct gcacgccatt ggcctgatcg
    45721 gtcgcattgc cagcaagatc aatactcttc tcgccagacg cggtttgatc gctggaagag
    45781 gtcgaggggg cttttagcgc agaaccgata ccgatgatca acagcagtag aaccagaatg
    45841 ccgacgccca tcatcatata ctgacgagaa gcgggtttac tggctgcttt tttgcgctta
    45901 cgcggacgac gctctacgcg ctcttcatcc acggtttcat cttcggattc gtcaatttct
    45961 tcttcgattt ccggttcctc attgcgctct ttttgcgcac gagtcggacg gcgatcgtca
    46021 gtgtcatcaa gttcaatatc atcaaaattg atctgcggtt cgccacgttc agtacgctca
    46081 gaacgttcag aagattgacg agaacgacca gtacgacgat cgctgggatc gggtttcagc
    46141 tcgtcttctg gtttgaattc atccatttaa caccccacta aaaggttaat gcttaccacg
    46201 ttgcaattaa cctgaagcta atagaccgct tgataagcgg cctgaccttt cttgttgtta
    46261 cgctgattga caatcggcaa tggcgttaag aacaagctcg tgcgaaacgc cgctgcgaac
    46321 ttcactctta ccaattgcca acggaagaat taagcgcatc tctcccgcaa ggactttctt
    46381 gtcacgcagc atatgcggta aatacgcctg cgcggacatt tcgcgcggcc cattgaccgg
    46441 taacccagcc cgcgtgagca gggttataat acgctgcgtt tcggcagaac taaactgccc
    46501 gagacgttcc gacgtccgcg ccgccatcac catacccgca gcgaccgctt caccatgtaa
    46561 ccaattgcca taccccattt cagcttcaat ggcatgacca aaggtgtgtc ccagattcag
    46621 taaagcacgt aacccggttt cgcgctcgtc ggcggcgaca acttctgcct tcagttcaca
    46681 acaacggcga atacagtacg ccattgccgg accgtccaga cgcaacaacg catccagatt
    46741 ctcttccagc cagttaaaaa acgcaccgtc aagaataatg ccgtatttga tgacttctgc
    46801 cagccccgac gctaactcac gcgggggaag cgttttcaga cagtcgagat ccaccaccac
    46861 tgaagcaggc tggtagaacg cgccaatcat gtttttaccg aggggatggt tgaccgcagt
    46921 tttgccgcca acggaggaat cgacctgcga cagtaacgtc gtcgggactt gaatgaaacg
    46981 aacaccgcgc tgataactcg ccgccgcgaa gccggtcaga tcgcccacta cgccgccgcc
    47041 aagcgccacc agcgtagtat cgcgaccatg cggcttttgt aacaacgccg taaagacggt
    47101 atcgagtaca gccaggcttt tatactgctc gccgtcaggg aggataacgc tatcgacgtt
    47161 aacacccgcc tgttcaagta cgccgcggac cttatcgaga tacagaggag ccagggtttc
    47221 gttggtgacc aacatgacct gctcgcccga tttcagcggt aagaatgaag ctggttcatt
    47281 aaacaaacca gatgcgatgg taattgggta actacgttcc ccgagagtaa cgacaatcct
    47341 ctccataacg cgacatccac cttaattact gtacccgcag acgagtgtat ataaagccag
    47401 aattagttgc tttccagcat gtgaataatc tggtttgcaa ccactttagc gctttgatca
    47461 tcagtacgaa tggtcacgtc ggcaatctct tcatacagcg gattgcgttc attggccaac
    47521 gcttccagaa cttcacgcgg cggtgtttca acgtgcagca acgggcgttt tttatcacgc
    47581 tgcgtgcgtg caagttgctt ttcgatggtc gtttcaagat aaacgacaac gccacgagcg
    47641 gaaagacggt tacgcgtttc acgggatttc acagagccgc cgccagtagc cagcacaata
    47701 ccctgtttct cggtcaactc attgatgacc ttttcttcgc gatcgcggaa gccttcttcg
    47761 ccttctaaat cgaaaaccca gcccacatca gctccggttc gtttctcaat ctcttgatcg
    47821 gaatcgtaaa attccatatt gagttgttga gctaactggc gcccaatagt gctttttccg
    47881 gcacccatag gcccaaccag aaagatattg cgtttctctg ccattttttc ggtactacta
    47941 agactattcg ttaatgataa acccgcttcg ctcagagagc gccgcaggac atgaactgaa
    48001 acctcataag atattgcgag agtcagactg aaaattatct caatactcca gcgggtttgg
    48061 caactgaata aatcacccat ccccctgcat atctggtcgc tgcaagcgcg ctgccttgct
    48121 accaccgctc tggcgataaa tcaccgggta agattagcgt aaaaaagaca gcaaaatgcc
    48181 gcctgaatga taaatcatca tcatggaacg caggcagcga agagcaccaa ctctcaaatc
    48241 ggtactcctt gtatgctaaa tacctgcgcg cgtcaaatag atgaaacacg ttcagcataa
    48301 aaacattacc gcttttacgg ctgtttactc actggaaacc agtcgtggcg tgataaacac
    48361 cactaactcg cgtcgttcat cttcttttcc gtcatgacga aataattgcc cgaaccaggg
    48421 aatgtcgcca agcaacggta cgctatcctg acccgattta tttttacggg taaaaatgcc
    48481 gcccagcgcc aacgtttctc cgcttttgac ctcgacctgc gtttcgatct cctgcttatc
    48541 aatcgccagc acttcgccat cggcctgctg tagcacctgc cccggaacgt tctggctgat
    48601 gtgtaatttc agccggatgc gacctttttg taacaccgtg ggcgtgacct ccatccccag
    48661 gacggcctct ttaaattcca ccgacgtcgc gccactttcc ccgctggaaa cctgatatgg
    48721 aatttcgctc ccctgtttaa tgctggcagg ctgaagatgt gaggccagca gacgcggact
    48781 ggcgataata tccagctgct gtttttgttc gagcgcagaa agctcaagat ccagcaagcg
    48841 tccgttgatg cgcccaatgt taaaaccgac atgcgttgtc gccgtcgcta cggagaggtc
    48901 gctaccaagc gtggtgactt gcccaacgcc accagcgtgt tgcgcatcgg ccagcgtcca
    48961 tttcacgcct aactcacgca aacttttttc attaatggtg acaatatgcg ccgacagctc
    49021 aacctgcccg accggcagat ccatttgcgc tacccactgt tcaagcgcgc ttaacgccgt
    49081 tttgttatct cgtagcaaaa ggcgattggt gcgtttatcg acggtcatac tccctttggc
    49141 actcagtagc ttctcccccg ctttcgccag ttctcccgcg tcggcgtatt gcagggttat
    49201 actgcgattt tccagcggca gatttgcctg cgcccgcgcc tgctccgcct cctggcgggc
    49261 gatattgtta ttctgccagg caatggaatg cactgagaga atgttgtctt cctgccgcgt
    49321 tatcagtccg gcgcttttca ctacagtttg tagtgcctgc ttccagggaa catctgttag
    49381 atgtaacgac accgtaccgc tgacgtctgg cgacacgacc aggttcaact tctcctgttc
    49441 agccagcgcc tgcaacacct gagctaccgg aacgtcatcc accatcagcg tcactttttg
    49501 cggctttgcc gcctgtacgc cgggtatcag catcaacagt agtgcggcta tccattgctt
    49561 catttgtatc tccttgccgt tgccacaacc attgtggcgg ttcgcagttt gtcccggttc
    49621 ccagcgttag tgcgtctggc gtcagctgta aaattgtcca gccgttttcc agcacatcgt
    49681 tttgctgcac ccgtcgccat ttcttttgcc cgtcttttat tacaccgatg atgcgctcgc
    49741 ctcgccctac catcccctga tagcgccact ggctaagttc gctaatccgg catagatctt
    49801 ccggcggttt aaaagggtca cgcataccgg ttaaaaggca caatgcaata cctgccaaca
    49861 accagcgttt aaccctcatg cggcgtctcc agttgtagcg tgaacaaaag atcatcacct
    49921 tccacgctta acgaaaaacg gctcacgctg acgttgcgct ctgccagccg tgtaaatgcc
    49981 gacggcactg cttcccacag cgttttcaac gccaactcac ctccctgcgc ggatggatgc
    50041 caggaaacca gttgcgcgcc ggataactga aaatccagag gcgaaaaggg cagcgttttt
    50101 tcctcgctga agggagtggt gtctaccagg cgatacagtg cggcccactg ctggtgatga
    50161 cttgcccgta gtcgaattaa tgcgtcgcgc tcttcatggt gtgtcgatga tagaaaaatg
    50221 agcgtaacta acatcagcaa ccagaatgcc cagcaaagct ggcggaggcg gggtgatgtg
    50281 gcgaaccacc agtcaaagaa catgttcatc gctaaccttc cttgttaact gatactcaaa
    50341 ttgccagcgt ccctgcgcat cctgctgcgt ggccccccgc tgattgagat gaaaagaagc
    50401 atcctggcga agtgacgttt ctagtgcgtt taacgcggta atgcttgttg taagcccctt
    50461 gatctccagc gttccctgct gccagcttat cgttgtcagc caggcgtgtt caggtaaaag
    50521 agccgccagt gcttccagcg cagattgcca gtcgcgggta aattgtcgct ggcgctgcct
    50581 ttgcaaacgc tgctcacgaa tttgttggcg ctccagcaaa cgtggtttcg ttatctgtaa
    50641 gctgtgggcg agttgttgtt ccccctgaag caaaacggcg tctacgcgag cttcggcgct
    50701 gcttgtcaga cgcagtatta gcgttatccc gacggccagc agcagaggcg caacgaacat
    50761 cagcaaccag aaacgcagaa aagcggtccg gcgttgctgt cgccagggca aaaaattaat
    50821 tggcgggttc atcagtacgc cttcccaagc gccagcccca gcgcgatggc aaagtctcca
    50881 cctgacggcg gtagcggcgg ctgacgaaca gaaacggcct cccagggatc aaatccccct
    50941 tcgccacata tcgcgacgct ttcgggatca acggataacg ctgccgccag ctccttcgcg
    51001 ctagtcatcc ccaccgccag tttgcgcccc cagcgatagc gtgtcgccca cagccactgt
    51061 tcgttatcac gccaggccag acattgctga tgagaaggta aaaaaggcag gaatcgctgt
    51121 aatgcactgg catccggggt gatcgcacta acatgaacac gcaacctttc tgccagagta
    51181 agcagcgttg ccagctcttt gctttgcgcg gcagtcacgt tataagcggg gctgagtgag
    51241 tcttcgctat aatcgaagcg cagggagtcc ggatccatat ccagctcgcg ggccatcgtc
    51301 cctgacagcc aggccgtttg ctcccgctca ccaagggaca tcgacgggcg cggaaatgac
    51361 cgctgtaatg tgcgactggc gggaaacgcc aacataatgt gatgacgctg cggcagttcg
    51421 cgactccaag gtaacaacgt tttagccagc tgctgcgcat caacaatccg cccatctttg
    51481 ataatgtcgt tctccagcgg caaccgccac cagcgttgca aaaagcattc ttttgcgccc
    51541 cgtacgatcg caaccgctac cgcttcttgc tgttgtaaat gcaaaccaat ttgccagatc
    51601 ttaaatgcca ttgtgatgat ctccttatca cccgtcactc tgacgggtat atcaatgcgt
    51661 ctggcttgcc tttatactac cgcgcgtttg tttataaact gcccaaatga aactaaatgg
    51721 gaaatttcca gtgaagttcg taaagtattt tttgatcctt gcagtctgtt gcattctgct
    51781 gggagcaggc tcgatttatg gcctataccg ctacatcgag ccacaactgc cggatgtggc
    51841 gacattaaaa gatgttcgcc tgcaaattcc gatgcagatt tacagcgccg atggcgagct
    51901 gattgctcaa tacggtgaga aacgtcgtat tccggttacg ttggatcaaa tcccaccgga
    51961 gatggtgaaa gcctttatcg cgacggaaga cagccgcttc tacgagcatc acggcgttga
    52021 cccggtgggg atcttccgtg cggcaagtgt ggcgctgttc tccggccacg cgtcacaagg
    52081 ggcgagtacc attacccagc agctggcgag aaatttcttc ctcagtccag aacgcacgct
    52141 gatgcgtaag attaaggaag tcttcctcgc gattcgcatt gaacagttgc tgacgaaaga
    52201 cgagatcctc gagctttatc tgaacaagat ttacctcggt taccgcgcct atggtgtcgg
    52261 tgctgcggca caagtctatt tcggaaaaac ggtcgaccaa ctgacgctga acgaaatggc
    52321 ggtgatagcc gggctgccga aagcgccttc caccttcaac ccgctctact caatggatcg
    52381 tgccgtcgcg cggcgtaacg tcgtactgtc gcggatgctg gatgaagggt atatcaccca
    52441 acaacagttc gatcagacac gcactgaggc gattaacgct aactatcacg cgccggagat
    52501 tgctttctct gcgccgtacc tgagcgaaat ggtgcgccag gagatgtata accgttatgg
    52561 cgaaagtgcc tatgaagacg gttatcgcat ttacaccacc atcacccgca aagtgcagca
    52621 ggccgcacag caggcggtac gtaataacgt gctggactac gacatgcgcc acggctatcg
    52681 cggcccggca aatgtgctgt ggaaagtggg cgagtcggcg tgggataaca acaagattac
    52741 cgatacgctg aaggcgctgc caacctatgg tccgctgctg cctgccgcag tcaccagcgc
    52801 caatcctcag caagcgacgg cgatgctggc ggacgggtcg accgtcgcat tgagtatgga
    52861 aggcgttcgc tgggcgcgtc cttaccgttc ggatactcag caaggaccga cgccgcgtaa
    52921 agtgaccgat gttctgcaaa cgggtcagca aatctgggtt cgtcaggttg gcgatgcatg
    52981 gtggctggca caagtgccgg aagtgaactc ggcgctggtg tcgatcaatc cgcaaaacgg
    53041 tgccgttatg gcgctggtcg gtggctttga tttcaatcag agcaagttta accgcgccac
    53101 ccaggcactg cgtcaggtgg gttccaacat caaaccgttc ctctacaccg cggcgatgga
    53161 taaaggtctg acgctggcaa gtatgttgaa cgatgtgcca atttctcgct gggatgcagg
    53221 tgccggttct gactggcagc cgaagaactc accaccgcag tatgctggtc caattcgctt
    53281 acgtcagggg ctgggtcagt cgaaaaacgt ggtgatggta cgcgcaatgc gggcgatggg
    53341 cgtcgactac gctgcagaat atctgcaacg cttcggcttc ccggcgcaaa acattgtcca
    53401 caccgaatcg ctggcgctgg gttcagcgtc cttcacccca atgcaggtgg cgcgcggcta
    53461 cgcggtcatg gcgaacggtg gcttcctggt ggacccgtgg tttatcagca aaattgaaaa
    53521 cgatcagggc ggcgtgattt tcgaagcgaa accgaaagta gcctgcccgg aatgcgatat
    53581 tccggtgatt tacggtgata cgcagaaatc gaacgtgctg gaaaataacg atgttgaaga
    53641 tgtcgctatc tcccgcgagc agcagaatgt ttctgtacca atgccgcagc tggagcaggc
    53701 aaatcaggcg ttagtggcga agactggcgc gcaggagtac gcaccgcacg tcatcaacac
    53761 tccgctggca ttcctgatta agagtgcttt gaacaccaat atctttggtg aaccaggctg
    53821 gcagggtacc ggctggcgtg caggtcgtga tttgcagcgt cgcgatatcg gcgggaaaac
    53881 cggtaccact aacagttcga aagatgcgtg gttctcgggt tacggtccgg gcgttgtgac
    53941 ctcggtctgg attggctttg atgatcaccg tcgtaatctc ggtcatacaa cggcttccgg
    54001 agcgattaaa gatcagatct caggttacga aggcggtgcc aagagtgccc agcctgcatg
    54061 ggacgcttat atgaaagccg ttcttgaagg tgtgccggag cagccgctga cgccgcctcc
    54121 gggtattgtg acggtgaata tcgatcgcag caccgggcag ttagctaatg gtggcaacag
    54181 ccgcgaagag tatttcatcg aaggtacgca gccgacacaa caggcggtgc acgaggtggg
    54241 aacgaccatt atcgataatg gtgaggcaca ggaattgttc tgattaaaaa ggcgcttcgg
    54301 cgccttttca gttggctgac aaagtgcatt tgtttatgcc ggatgcgggt gaacgcgtta
    54361 tccggctaac aaaatcgtga aaaatcaata tattgtagga aacccataag cctgataagc
    54421 gttgtgcatc aggcaaactt cacgcattta cactcgcccc tgccctttca accattcgcg
    54481 cacgaggaac agcgcgctga cattacgcgc ttcgttgaag tcagggtctt ccagcaaatc
    54541 catcatatgc gccagcggcc agcgcacctg tggtagcggc tctggctcat cgccttccag
    54601 cgattccggg tagagatctt gcgcgaccac gatattcatt ttgctggaaa agtaagacgg
    54661 tgccatgctg agcttcttca aaaaagtcag atcgttcgca ccaaatccaa cctcttcttt
    54721 tagctcgcgg ttagcggctt cgtagacgct ttcacccgga tcaattaatc ctttcgaaaa
    54781 acctaattcg taggattcag ttcccactgc gtattcgcgg atcaggatca ggtgatcgtc
    54841 cacaatcggc acaatcatca ctgcttcccg gttggttgga cgcattcgtt cataaacacg
    54901 ccgcacgcca ttgctgaact ccagatccac gctctcgacg gtaaacagtc gggaacgggc
    54961 tacagtttca acattcagaa tggtgggttt ttgtaatgat ttgctcatcg tgggatctat
    55021 gctgtgaaat cagcggttat tgtgcgatat cggacacgct ttcggcaatg tgaattgcat
    55081 gttatttaca tttatgtaac ttaataaata atcgtcctca aatcaaatta aaagtcaata
    55141 ggttgaaata actccaggaa tttgctgata ttccgccttc agagggtttg ctatgatcag
    55201 cggttactgt gatgtgctta atgatgctca agttaaactc cacgcttgcc gatagccaac
    55261 cgcagaatca tgtattgtgt ctggtgcgac tgaccacgcc tgacagacta agtaagatgg
    55321 ggaaagcatg agcaccattg tgattttttt agctgctttg ctggcctgct cactacttgc
    55381 gggatggctg ataaaagtgc gatccagacg gcgtcagctg ccctggacca acgccttcgc
    55441 ggatgcgcaa acgcgtaaac tcacacctga agaacgtagc gccgttgaaa attatcttga
    55501 gagcctgacg caggtattac aggtgcctgg cccaacggga gccagcgcgg caccgatctc
    55561 tctggcgctg aatgccgaaa gcaacaacgt catgatgctg acacacgcta tcacgcgtta
    55621 cggcatctct accgacgatc cgaataaatg gcgttactac ctcgattcgg tagaagtcca
    55681 cctgccccct ttctgggaac aatacatcaa cgatgagaat accgttgaac tgatttatac
    55741 cgattcgctg ccgctggtta tttcactcaa cggtcatacg ctgcaggagt acatgcagga
    55801 aacgcgcggc tatgccttgc aacctgttcc gtccacgcag gcgtcgattc gcggggaaga
    55861 gagtgagcaa atcgagctac tcaatattcg caaagaaacg catgaagaat atgcgctgag
    55921 tcgtccgcgc gggctgcgtg aagcgttgct gatcgtcgcc tccttcctga tgttcttttt
    55981 ctgcctgatt accccagatg tatttgttcc gtggctggca ggcggcgcat tactgctgct
    56041 gggcgcaggt ctgtgggggc tattcgcgcc cccggcaaaa tcctccctgc gagaaattca
    56101 ttgtctgcgc ggtacacccc gtcgttgggg attgtttggc gaaaacgatc aggaacagat
    56161 caacaatatt tcactcggta ttatcgacct ggtctatccc gcacactggc agccatacat
    56221 tgctcaggat ctcggtcaac aaaccgatat tgatatctat ctcgaccgcc acgtagtgcg
    56281 tcaggggcga tatctttcgc tgcatgatga agtaaaaaac tttccgttac agcactggct
    56341 gcgcagtacg attatcgctg cgggctcgct gctggtgctg tttatgctgt tattctggat
    56401 cccgctggat atgccgctga aattcactct ctcatggatg aaaggcgcgc agaccattga
    56461 agccaccagc gtaaaacaac tggctgacgc tggcgtgcgg gtaggcgata cattgcgtat
    56521 tagcggtacg ggaatgtgta atattcgcac ttccggaacc tggagcgcga aaaccaattc
    56581 acctttttta ccgtttgact gctcgcagat catctggaat gacgcccgct cattaccatt
    56641 accagaatct gaactggtca acaaagcgac ggcattgact gaagcagtta atcgccagct
    56701 gcaccctaaa ccggaagatg aatctcgcgt cagtgcctca ttacgttcag cgattcaaaa
    56761 atccggcatg gtattgcttg atgattttgg cgacattgta ctgaagacag cggatttatg
    56821 ttctgccaaa gatgactgtg tgcgactgaa aaatgcgctg gtcaatctcg gcaacagtaa
    56881 agactgggac gcgctggtaa aacgcgccaa cgccgggaag ctcgatggcg tgaatgtgtt
    56941 attacgcccg gtgagtgcag aatcgctgga taacctggtg gcaacctcca ccgcgccgtt
    57001 tatcacgcat gaaacggcgc gagcggcaca atcactaaac agtccggccc ccggcggatt
    57061 cctgattgtc agcgacgaag gcagcgattt tgttgatcag ccctggcctt cggcatcact
    57121 ttacgactac ccgccgcaag aacagtggaa cgctttccag aaactggcac aaatgctgat
    57181 gcatacgccg tttaacgccg aaggtatcgt cacaaaaatc ttcactgacg ccaatggtac
    57241 gcagcatatt ggccttcatc cgatcccgga tcgttccggc ctgtggcgct atctcagcac
    57301 cacattgctg ctactgacga tgctgggtag cgccatttac aatggcgtac aggcctggcg
    57361 tcgttaccag cgtcatcgca ctcgcatgat ggagattcag gcctattatg aaagctgcct
    57421 gaacccgcaa ctgatcaccc cttcagaaag ccttatcgaa taacacgttt gcgcggcagg
    57481 ttatgctacc ctgtcgcgca aattgcttca ctctggagat ttccctcatg catatcaaca
    57541 ttgcctggca ggacgtagat accgttctgc tggatatgga cggcacgttg ctcgacctcg
    57601 ccttcgataa ctatttctgg caaaagctgg tgcctgaaac atggggcgcc aaaaacgggg
    57661 ttacgccaca ggaagcgatg gaatatatgc gccagcaata tcacgacgta cagcatacgc
    57721 taaactggta ctgtcttgat tactggagtg agcaactggg tctggatatc tgtgcgatga
    57781 ccaccgagat gggaccgcgt gccgtactgc gtgaagatac cattccgttt cttgaggcac
    57841 tgaaagccag cggtaagcag cgaattttgc tcaccaatgc gcatccgcac aacctggcgg
    57901 taaaacttga gcataccggt ctggacgcac accttgattt attactttcc acccacacat
    57961 ttggttatcc gaaagaggat cagcggttat ggcatgcggt ggccgaagct acgggtctga
    58021 aagctgaaag aacgctgttt attgatgaca gcgaagcgat tctcgatgct gccgcgcaat
    58081 ttggtattcg ttactgcctc ggcgtgacta atcctgattc cgggattgcc gagaaacagt
    58141 atcaacgcca tccgtcactg aatgactacc gccgcctgat cccctcgcta atgtgaagga
    58201 gacgccatga aagagaaacc tgctgttgag gttcgactgg ataaatggct atgggctgcc
    58261 cgtttttata aaacccgcgc gctggcccgt gaaatgattg aaggcggtaa ggtgcattac
    58321 aacgggcagc gcagcaagcc gagcaaaatc gtcgagctga atgccacgct cactctgcgc
    58381 cagggaaatg acgaacgcac ggtgattgta aaggcgatta ctgaacagcg tcgccccgcc
    58441 agcgaggcag ccttgctgta tgaagagact gcggaaagtg tagagaaacg cgaaaaaatg
    58501 gcgatggcac gtaaacttaa tgccttaacc atgccgcacc cggaccgacg cccggacaaa
    58561 aaagagcgcc gcgacctgtt acgatttaaa cacggcgaca gtgaataact gtcacctgca
    58621 agagagatga ttatgccgca acatgaccaa ttacatcgct atctgtttga aaattttgcc
    58681 gttcgcggcg aactggtaac cgtttcggaa accctgcaac agatccttga gaaccacgat
    58741 tatccgcagc ccgttaaaaa cgtgctggca gaactgctgg ttgcgaccag cctgttaacc
    58801 gctacgctga agtttgatgg tgatatcacc gtacagctgc aaggcgacgg tccgatgaat
    58861 ctggcggtta ttaacggtaa caataaccag caaatgcgcg gtgtggcgcg cgtgcagggc
    58921 gaaattccag aaaatgccga cctgaaaacg ctggtcggca atggttacgt ggtgatcacc
    58981 attaccccga gcgaaggcga acgctatcag ggcgtggttg gtctggaagg tgataccctg
    59041 gcggcctgcc tggaagatta ctttatgcgt tctgaacagc tgccgacgcg cctgtttatt
    59101 cgcaccggcg acgtagacgg caaaccggct gcaggcggta tgttgttgca ggtaatgcct
    59161 gcgcaaaatg cccagcagga cgactttgac cacctggcga cgctaaccga aaccatcaaa
    59221 accgaagaac tgctgacctt accggcaaac gaagtgttgt ggcgtttgta tcacgaagaa
    59281 gaggtgacgg tttacgatcc gcaggatgtg gagttcaaat gcacctgctc gcgtgaacgt
    59341 tgcgccgatg cgctgaaaac gctgcctgat gaagaagttg atagcatcct ggcggaagat
    59401 ggcgaaattg acatgcattg tgattactgc ggtaaccact atctgttcaa tgcgatggat
    59461 attgctgaaa tccgcaacaa cgcgtctccg gcagatccgc aagttcatta atgagtatgt
    59521 ccggcagaga gggctctgcc ggattttacg acgtaatggc ctgatgtgct gcgcttacca
    59581 ggcctgtgaa ataaatcgca aattattgtt ggtcagatac agcgtcgtat ccgttaaaag
    59641 agttgtcact tacttaagtt tatttccagc gtttcaccat ctaccgtcag atcgcgccac
    59701 gctttcggcc tcgtccccag ttttccatcc ttcgcagctg tgagtaattt ttctttcgtt
    59761 atttcgttcg gaagtaaact catatcaagc gcgtcccatt cttttctgtc tgagtcaaag
    59821 ccatagacaa tgactctgtc atcattaaaa gcaaacagga tccgctccgc ctgaccatca
    59881 ctattcagat cttgctcgac caggacgcag gcgtcttttt caatacaggt catcacgtta
    59941 tagcgatcct ggattaaggc cgaccagaat gtcgcatccg gtttaacaga accaggggca
    60001 attaacacat tttcggctaa tactttttcc gatacctgtt cctgaagatg ttgctctcca
    60061 tctaacgcca tcagcagatc ccgcgcgcgt ttcgggtctt tcataaaccc ggcatcgctt
    60121 ttcagcgact caagcgcagc acgtccatag cgaccgctct gctcgagcat gtagatagtt
    60181 acctggtctg acgtgttttt gccgctctga taacgcgcca tatggctgtt cacgctaatg
    60241 cgcatactgt ccagcaccgg cgaattaaga agcaccagta tcaccaacac caataacgaa
    60301 accgcaaggt tcactttgcc ctgaagaaca acgggatttt gccctttacg ccagacgatg
    60361 ctgacaaaat accccagcga ccacaccagt aacaccagca ccgccagcac gccctgcaag
    60421 cggtcgacag tccagccgta ctgagcgacc cgcagccata acgcccaggc ggcgacgaac
    60481 acatacagcg gagcaaccag caaagcggtt ttaatcaggc aacgcaacgg ccctgtccag
    60541 ggaagtgacg ctttttgcgg atcgcggaca atagccatta agatcaattg caaaaaggcc
    60601 agcgttaaca gcaacccggc ggcggagatg tggcgagaaa tcgcgctcag gcccgtaaac
    60661 ggcagagtga tgataaacat cagggttagc aatgatacta acggcagcaa ccccgtggcg
    60721 attaacgtga acaacttttg aatagagtcg attaaacgtg actgtgttcg cgcgaggatc
    60781 accgccagcg cggtaaccag acctaacgtg agataaataa accagtcggt tgcaaaaaag
    60841 agcgtattga aaaacgtgat gccaacaagt ttaaacaact cactccacag taaaagcacc
    60901 agccacgtca agccattggc gagaaaaatc accagtaata taagtacgtt atgccatact
    60961 gactggtaaa aatagcgata gcggctactg tcattgcgga tgcgaaggct ttgttgtatc
    61021 cacggtagca acaacattgc catcagcagc agatagcaac caaaatccca aagcgccttt
    61081 tcagctctcc aggggttcat gccatcagtt tgccacttca gccagccgct catccccagc
    61141 gtggcaataa acaccagcgc cagccatccc caaaggcgct tctgtttaaa agagatcacg
    61201 gagaagagta aaacggatga aaacgcaacg gtcgcaggca cgccataaac aatccaactg
    61261 tgattttttc cggcaagcca ggcgatcaac aggtagcaaa ccagcccctg aagtaatccg
    61321 gtagcaatca tcccccagcg tgttgccggt gaaagttcaa cgttatccat gttggttatc
    61381 cagaatcaaa agtgggttaa ttatcgcatc cgggcagtag tattttgctt ttttcagaaa
    61441 ataatcaaaa aaagttagcg tggtgaatcg atactttacc gattgaattt gcatcaattt
    61501 cattaaggaa tgcgattcca ctcacaatat tcccgccata taaactaaga tttaaccttt
    61561 tgagaacatt ttccacacct aaaatgctat ttctgcgata atagcaaccg tttcgtgaca
    61621 ggaatcacgg agttttttgt caaatatgaa tttctccaga tacgtaaatc tatgagcctt
    61681 gtcgcggtta acacccccaa aaagacttta ctattcaggc aatacatatt ggctaaggag
    61741 cagtgaaatg cgcgttaaca atggtttgac cccgcaagaa ctcgaggctt atggtatcag
    61801 tgacgtacat gatatcgttt acaacccaag ctacgacctg ctgtatcagg aagagctcga
    61861 tccgagcctg acaggttatg agcgcggggt gttaactaat ctgggtgccg ttgccgtcga
    61921 taccgggatc ttcaccggtc gttcaccaaa agataagtat atcgtccgtg acgataccac
    61981 tcgcgatact ttctggtggg cagacaaagg caaaggtaag aacgacaaca aacctctctc
    62041 tccggaaacc tggcagcatc tgaaaggcct ggtgaccagg cagctttccg gcaaacgtct
    62101 gttcgttgtc gacgctttct gtggtgcgaa cccggatact cgtctttccg tccgtttcat
    62161 caccgaagtg gcctggcagg cgcattttgt caaaaacatg tttattcgcc cgagcgatga
    62221 agagctggca ggtttcaaac cagactttat cgttatgaac ggcgcgaagt gcactaaccc
    62281 gcagtggaaa gaacagggtc tgaactccga aaacttcgtg gcgtttaacc tgaccgagcg
    62341 catgcagctg attggcggca cctggtacgg cggcgaaatg aagaaaggga tgttctcgat
    62401 gatgaactac ctgctgccgc tgaaaggtat cgcttctatg cactgctccg ccaacgttgg
    62461 tgagaaaggc gatgttgcgg tgttcttcgg cctttccggc accggtaaaa ccaccctttc
    62521 caccgacccg aaacgtcgcc tgattggtga tgacgagcac ggctgggacg atgacggcgt
    62581 gtttaacttc gaaggcggct gctacgcaaa aactatcaag ctgtcgaaag aagcggaacc
    62641 tgaaatctac aacgctatcc gtcgcgatgc gctgctggaa aacgtcaccg tgcgtgaaga
    62701 tggcactatc gactttgatg atggttcaaa aaccgagaac acccgcgttt cttatccgat
    62761 ctatcacatc gataacattg ttaagccggt ttccaaagcg ggccacgcga ctaaggttat
    62821 cttcctgact gctgatgctt tcggcgtgtt gccgccggtt tctcgcctga ctgccgatca
    62881 aacccagtat cacttcctct ctggcttcac cgccaaactg gccggtactg agcgtggcat
    62941 caccgaaccg acgccaacct tctccgcttg cttcggcgcg gcgttcctgt cgctgcaccc
    63001 gactcagtac gcagaagtgc tggtgaaacg tatgcaggcg gcgggcgcgc aggcttatct
    63061 ggttaacact ggctggaacg gcactggcaa acgtatctcg attaaagata cccgcgccat
    63121 tatcgacgcc atcctcaacg gttcgctgga taatgcagaa accttcactc tgccgatgtt
    63181 taacctggcg atcccaaccg aactgccggg cgtagacacg aagattctcg atccgcgtaa
    63241 cacctacgct tctccggaac agtggcagga aaaagccgaa accctggcga aactgtttat
    63301 cgacaacttc gataaataca ccgacacccc tgcgggtgcc gcgctggtag cggctggtcc
    63361 gaaactgtaa tgatttgaag ctggagaata tctatccagt atcttataga aagcaaaacg
    63421 ggaggcacct tcgcctcccg tttatttacc cttcttttgt cgtgccctgc gcccgcgtta
    63481 ccggcactgg cagccaggcg cgaatggaaa gcccgccccg ctcgctggtg ccaagctcca
    63541 gcatcccgtt atggttatcc acgatacgct gcacaattgc cagccctaat cccgtgccgc
    63601 taatggtgcg cgcactgtcg ccgcggacaa acggctggaa caggtgctta cgttgttccg
    63661 gcgcaattcc cggaccgtca tcttccacct ggaaccaggc gcgattcggc tccgttccgc
    63721 tgctgacttt gatccagcca ttgccataac gggcggcgtt gaccaccata ttcgccaccg
    63781 cgcgtttgat cgacagcggg tgcattttca cttcaatgct gccggggtaa agcgcggttt
    63841 caatttcccg ctcatagcca ctttcggcag caatcacctc accgagtact gcattaagat
    63901 ccgccatttc catcggcatc tcctgcccgg tgcgcaggta gtcgataaac tgctcaatga
    63961 tggcgttgca ctcttcgata tctttattga tcgattctgc cagatagcca tcctgctcgc
    64021 tcatcatctc agtcgccagg cgaatacgcg tcagcggcgt gcgcaagtcg tgacttaccc
    64081 ccgccatcag cagcgtgcgg tcatccgcca gttgcttaac accagccgcc atatggttaa
    64141 aggcacgggt aacggaacgc acctccgaag cgccatactc acgcagcggc ggcggaataa
    64201 tccctttacc aacctgcaag gctgcgtgtt cgagatcgac caacggtcgg ttctggatac
    64261 gaataaacag ccacgccccg cctatcgcca atagcataat cgccagcgta tagcggaaca
    64321 gcggagagaa atcgccctga tgaatttcgg tcagcggcac gcgtacccag atattgggcg
    64381 acagccaggt tttcagccag acgacaggcg aacttttgtt gacctcaacg cgcacttccg
    64441 tcgggccgcc cagttgctgt gccatctgat ggcttaagaa ttcatagtgt tgcgcccaac
    64501 gcagacctgc ctcttcggca gcctcgttgg agtagagaga gatccccagc tcacggtaga
    64561 tctcccgacg gaaagcggga ggcacaacca actgcgtgcc gtcctccagt tgcagtttgt
    64621 cggtcatcaa catacgcact tcgtacgcga ggactttatt aaactgctgg aggctcggca
    64681 aaatcgcgaa gttcagcacc accagataag tcgtcaccag gctggcgaac agcaaggtga
    64741 cgatgagcaa taacgtacgg gcaaatgaac ttcgtggcga gaagcgcaat cgcctcatgc
    64801 tttagagccg tccggtacaa agacgtagcc caggccccaa acggtctgaa tgtaacgcgg
    64861 atgcgctgga tcttcttcta ccatgcggcg cagacgcgaa atctgcacgt cgatggagcg
    64921 ttccattgcg gaatattcac gaccacgggc aaggttcatc agcttatcgc gggagagcgg
    64981 ctcacgcgga tggctgacca gtgccttcag taccgcaaac tcaccgctgg tgagcggcat
    65041 cggctcatct tcgcggaaca tttcgcgcgt accgaggtta agtttgaact taccgaaagc
    65101 aattaccgcc tcttcctgtg acggtgcgcc tggcagttcg ttcgcctgac gacgcagcac
    65161 cgcacgaata cgggccagca gttcacgcgg gttaaacggt tttggaatgt agtcgtcagc
    65221 gccaatctcc aggcctacga tacggtccac ttcttcccct ttcgccgtca ccataatgat
    65281 cggcatcggg ttgctctgac tacgaagacg tcggcaaatc gacaagccat cttcaccagg
    65341 taacattaaa tccagtacca taagatggaa agattcacga gtcagcaggc gatccatctg
    65401 ttctgcatta gcgacgcttc gaacctggaa gccttgttcg gtgagataac gttccagcag
    65461 cgcacgcagg cgcatgtcgt catcgaccac cagaatcttg tagttctctt gcattgtttg
    65521 tactcccaaa ggttcgcaac aatttgtaag cgtgtattct taaaaaagct cacgttcgtc
    65581 accagctaaa tctggtatga atttcagcct aaattgttac aaagcatatt aaacagcagc
    65641 ttaagtatac aatttattcg gcgaaacatt attgattctg ttgatatgat cacgttatac
    65701 ccaatgtgcg cattatcaaa cagacaaagg gaatcaacga gatgaaaacg cccctggtta
    65761 cccgggaagg gtatgaaaaa ctcaaacaag agcttaatta tctctggcgt gaagaacgcc
    65821 cggaggtcac aaaaaaggtg acctgggccg caagtctggg cgaccgcagc gaaaatgctg
    65881 actatcagta taataaaaag cgtctgcgtg aaatcgaccg tcgcgtgcgc tatctcacta
    65941 aatgcatgga aaatctcaaa atcgtcgatt actcccctca gcaggaaggc aaagtctttt
    66001 ttggcgcgtg ggtggagatt gaaaacgacg atggcgtgac tcaccgtttc cgtattgtcg
    66061 gctacgatga aatttttggc cgtaaagatt acatctctat cgattccccg atggcccgcg
    66121 cattgctgaa aaaagaagtc ggcgatctgg ctgtggtgaa tactcctgcc ggggaagcga
    66181 gctggtatgt taatgctatc gagtacgtga aaccgtaagg aagagtctta acctcctgcc
    66241 gatggctggc atttttgcca gccagtccgt ataactatcc cctgattttt gatccgaaaa
    66301 gatgaactca aaccatgatg aatgattcgt tctgccgcat tattgcgggt gaaattcagg
    66361 cgcgcccgga acaggttgac gctgccgttc gcctgcttga cgaagggaat accgtgccgt
    66421 ttatcgcacg ttatcgtaag gaaatcaccg gcggtctgga tgacacgcag ctgcgtaatc
    66481 tggaaacgcg tctgagctat ctgcgcgagc tggaagagag acgtcaggcg atcctcaaat
    66541 ccatttccga gcaaggcaaa ctcaccgatg atctggcgaa ggccatcaac gccaccctaa
    66601 gcaaaaccga actcgaagac ctctacctgc cctacaaacc taaacgccgc acccgcgggc
    66661 aaatcgccat tgaagcaggg cttgagccgt tggctgacct gctgtggagc gatccgtcac
    66721 acacgccaga agtcgcggct gcacaatatg ttgatgccga taaaggcgtg gcagatacca
    66781 aagccgcgct ggacggcgcg cgctatatcc tgatggaacg ttttgccgaa gatgccgcgc
    66841 tgctggcgaa agtgcgtgat tatctgtgga agaacgcgca tctggtctca accgtggtga
    66901 gcggtaaaga agaggaaggg gcaaaattcc gcgactattt cgatcatcac gaaccgttgt
    66961 ccacggtgcc ttctcaccgc gcgctggcga tgttccgtgg gcgtaacgaa ggcgtactcc
    67021 agctttcgct gaatgccgat ccgcagttcg atgagccgcc caaagagagc tattgcgagc
    67081 aaatcatcat ggatcacctt ggcctgcgcc tgaacaatgc cccggcggat agctggcgca
    67141 aaggcgtagt gagctggacc tggcgcatca aggtgctgat gcatctggaa accgaactga
    67201 tgggtaccgt gcgcgaacgc gcggaagatg aagcaatcaa cgtctttgcc cgtaacctgc
    67261 acgatctgct gatggcggcc cctgccggac tgcgtgcaac gatgggcctc gatccgggtc
    67321 tgcgtactgg ggtaaaagtg gcggtggtcg atgccactgg caaactggta gcgaccgata
    67381 ccatttaccc gcacaccgga caagccgcaa aagcagcgat gactgttgct gcgctgtgtg
    67441 aaaagcataa cgttgaactg gtggcgatcg gcaacggtac agcttcccgc gaaaccgaac
    67501 gtttctatct cgacgtgcag aagcagttcc cgaaagtgac cgcacagaaa gtgatcgtca
    67561 gcgaagctgg cgcgtcggtt tactcagctt ccgagctggc agcgcaggag ttcccggatc
    67621 tcgacgtttc gctgcgtggt gcggtatcta tcgcccgccg tttgcaggat ccgctggcgg
    67681 agctggtgaa aatcgatccg aaatctatcg gcgtaggtca gtatcagcat gacgtcagcc
    67741 agacgcaact ggcccgcaaa ctggatgcag tagtagaaga ctgcgtaaac gccgttggcg
    67801 tcgatctcaa caccgcttct gttccgctat taacccgcgt ggcgggcctg acgcgcatga
    67861 tggcgcaaaa catcgtggcc tggcgcgatg agaacggcca gttcaagaac cgtcagcaac
    67921 tgctgaaagt cagccgtctg gggccgaaag ccttcgagca gtgcgcgggc ttcctgcgca
    67981 ttaaccacgg tgataacccg ctggacgcct ctaccgttca cccggaagcc tatccggtgg
    68041 tggaacgcat tctggcagca acacagcagg cactgaaaga tctgatgggt aacagcagcg
    68101 aactgcgtaa cctgaaagcg tctgacttta ctgatgaaaa attcggtgtg ccgacagtaa
    68161 ctgacatcat caaagagctg gaaaaaccgg gtcgcgatcc gcgtccggaa tttaaaaccg
    68221 ctcagtttgc cgatggcgtc gagacaatga acgacctgca accgggtatg atcctcgaag
    68281 gcgctgtcac caacgtcacc aactttggcg cgtttgtcga tattggcgtg catcaggacg
    68341 gcctggttca catctcttca ttgtcgaaca agtttgtgga agatccgcat accgtggtga
    68401 aagcgggcga cattgtgaag gtgaaagtgc tggaagtgga tcttcagcgt aaacgtatcg
    68461 ccctgaccat gcgtctggac gagcagcctg gcgaaaccaa cgcccgtcgc ggcggcggta
    68521 atgaacgccc gcaaaacaac cgcccggcag ccaaaccacg cggtcgtgaa gcgcagcctg
    68581 ccggtaatag cgcgatgatg gatgcgctgg cggcggcaat gggcaaaaaa cgttaaacgc
    68641 cctgattgac ccctaaacct gcgcgataag gtgtccacgc cgcatctggc aacgaacgcc
    68701 ttgtctgaca taaaagtgcc ggagaatatc tccggccttt ttattccaca accaaactca
    68761 taatatattc cggcaatatt tatcacttca ttaacaactg aaaccttaat taaacattag
    68821 ccagtccggg taattcacta ttcgaattat attttcgctg cgatataacc ttgagccaca
    68881 tcaacattga gtcagattat tattcaaacc aacattcgca cacattttaa gtattgctga
    68941 tagaaaccat tctcattatc attgtgttgt tgattattta atctctcctt tgttggcaaa
    69001 tcatctggtc tcatgtcgct gtcaaacgcc ccatgaggta gttatccagt taatgagaaa
    69061 caagtaggca cctatgcaat acactccaga tactgcgtgg aaaatcactg gcttttcccg
    69121 tgaaatcagc ccggcatatc gccaaaaact gctttctctt ggcatgttac ctggctcctc
    69181 ttttaatgtg gtgcgcgtcg ctccactcgg cgaccccatt catatcgaaa cccgtcgtgt
    69241 gagcctggta ttacgcaaaa aagatctggc cttattagaa gtggaagcgg tttcctgtta
    69301 atacggtgat aacaacaatg aaaaaattaa ccataggctt aattggtaat ccaaattctg
    69361 gcaagacaac cttatttaac cagctcactg gcgcacgtca gcgtgtaggt aactgggctg
    69421 gcgttaccgt cgaacgtaaa gaagggcaat tctccaccac cgatcatcag gtcacgctgg
    69481 tggacctgcc cggcacctat tctctgacca ccatctcatc gcagacctcg ctcgatgagc
    69541 aaatcgcctg tcactacatt ttgagtggcg acgccgacct gctgattaac gtggtggatg
    69601 cgtctaacct tgagcgtaac ctgtacctga cgctacaact gctggaactc ggcattccct
    69661 gcattgtggc actgaacatg ctcgacattg ccgagaagca aaatattcgt attgaaattg
    69721 atgctctgtc ggcgcgtctt ggctgcccag tgatcccgct ggtttcaacc cgtggtcgcg
    69781 gtattgaagc gctcaagctg gcgattgatc gctataaagc taacgagaat gtggaactgg
    69841 tgcattacgc acagccgcta ctcaacgaag cagattcact ggcaaaagtg atgccttccg
    69901 acatcccgct gaaacaacgt cgctggctgg gcctgcaaat gctggaaggc gatatctaca
    69961 gccgcgccta cgccggtgaa gcgtcgcagc atctggatgc cgccctcgcc cgtctgcgta
    70021 atgagatgga cgatccggcg ctgcacattg ccgatgcgcg ttaccagtgc attgctgcca
    70081 tctgtgatgt ggtaagcaac accctgacgg cagaacccag ccgtttcacc actgcggtag
    70141 ataaaatcgt gctcaaccgt ttcctcggtc tgccgatttt cctctttgtg atgtacctga
    70201 tgttcctgct ggctatcaac atcggcgggg cgttacagcc gctgtttgac gtcggctccg
    70261 tggcgctatt tgtgcatggt attcaatgga ttggctacac gctccacttc ccggactggc
    70321 tgactatctt cctcgcccag ggcctgggtg gcggcattaa caccgtgctg ccactggtgc
    70381 cgcagattgg catgatgtac ctgttcctct ccttccttga ggactccggg tatatggcgc
    70441 gtgcggcgtt tgtgatggac cgtctgatgc aggcgctggg cttgccgggg aaatcctttg
    70501 tgccgttgat cgtcggtttc ggttgtaacg taccgtcggt aatgggtgca cgtacgcttg
    70561 atgcaccgcg tgaacgtctg atgaccatca tgatggcacc gtttatgtcc tgcggcgcgc
    70621 gtctggctat cttcgcagta ttcgcggctg ccttcttcgg gcagaacggt gcgctggcgg
    70681 tcttctcgct gtatatgctg ggtattgtga tggcggtgct gactggcctg atgctcaagt
    70741 acaccatcat gcgcggtgaa gcgacgccgt ttgtcatgga gttgccggtc tatcatgtac
    70801 cacacgttaa aagcctgatt atccagacct ggcagcgtct gaaaggcttc gttctgcgtg
    70861 ctggtaaagt gatcatcatc gtcagcattt tcctgagcgc tttcaacagc ttctcgctga
    70921 gcgggaaaat cgtcgataac atcaacgact cggcgctggc ttccgtcagc cgggtgatca
    70981 ccccggtctt caagccgatt ggcgtacatg aagataactg gcaggcaacg gttggcctgt
    71041 ttacgggcgc aatggcgaaa gaagtggtgg tgggtacgct caacaccctc tacaccgcag
    71101 aaaatattca ggacgaagag ttcaatccgg cggaattcaa cctcggtgaa gagctgttca
    71161 gtgcggtaga tgaaacctgg cagagcctga aagacacctt cagccttagc gtactgatga
    71221 accccattga agctagcaaa ggcgacggcg aaatgggtac cggggcgatg ggcgtgatgg
    71281 atcagaaatt cggtagcgca gctgccgcat acagctacct gattttcgtc ctgctgtatg
    71341 taccgtgtat ctcggtgatg ggggctatcg cccgtgaatc aagccgtggc tggatgggct
    71401 tctccatcct gtgggggctg aatatcgctt actcactggc aacattgttc tatcaggtcg
    71461 ccagctacag tcagcatcca acttacagcc tggtgtgcat tctggcggtt atcctgttta
    71521 acatcgtggt tatcggtctg ctgcgccgcg cgcgtagccg ggtggatatc gaactgctgg
    71581 caacccgcaa gtcggtaagc agttgctgcg cagccagcac caccggtgat tgccattaat
    71641 ggcttcactt attcaggtgc gcgatttgct ggcgttacgg ggccgtatgg aagcggccca
    71701 gataagccag acattgaaca ctccacagcc aatgattaac gccatgctgc aacaactgga
    71761 aagtatgggc aaagccgtgc ggattcagga agaacctgac ggctgcctct ctggcagttg
    71821 taaaagctgc ccggaaggaa aagcctgtct gcgcgagtgg tgggcgctgc gttaacctta
    71881 ctccatcgcc tgttttggaa agcccggtat gcgtctgcat ccgggctttt ttgcgtgcgg
    71941 ctttccataa aaatgcaact cttgcagcac ggcgtaagtt cctttgaaag catctcgcag
    72001 ggatgaaaac tcgctaatac acaggagtga agtggcgcgt agagtcgcgg cattcaaaca
    72061 acaggtgaag gaacgccatg agcaaaaagc agagttccac cccacacgat gcgctgttca
    72121 aactcttttt acgccaaccg gacacggctc gtgattttct tgcgtttcat ttaccggcac
    72181 ccattcacgc gctttgtgat atgaaaaccc tcaagctgga gtcgagcagc tttattgatg
    72241 acgatctgcg tgaaagctat tccgatgtgc tgtggtcggt gaaaacggaa caaggaccag
    72301 gatacatcta ttgtctgatt gaacatcaaa gcacctcaaa caaactgatc gcatttcgca
    72361 tgatgcgtta cgctattgcc gcaatgcaaa atcaccttga tgccggatac aaaacgttgc
    72421 cgatggtggt gccattgttg ttttaccacg gtattgaaag cccctatccc tattcgctgt
    72481 gttggctgga ttgtttcgcc gatcccaaac tggcaaggca gctttatgcc tccgcatttc
    72541 cgctgattga tgtcaccgtc atgcctgatg atgaaatcat gcagcaccga cgtatggcgc
    72601 tgctggagtt aattcaaaaa catattcgtc aacgcgacct gatggggcag gtagagcaaa
    72661 tggcctgctt attaagtagt ggatacgcta atgacagaca aatcaaaggg ctgtttaatt
    72721 acatactgca aaccggcgac gcggtacgtt ttaacgattt tatcgacggc gttgccgaac
    72781 gttcaccgaa acacaaggag agtttaatga caattgcgga aagattgcgg caggaggggg
    72841 aacaatccaa agccctgcat atagccaaaa taatgcttga atccggagtc cctcttacag
    72901 acatcatgcg ctttaccggg gtgtcagaag aagagttggc tgcggcgagc cagtaaattt
    72961 ctgtctcgcc atttcaaaag ttgcctacac cctctgcttc aacgccacca gcaggtgaca
    73021 aaactcgacc ggatgcgaaa taaacggcgc atgggccgct ttggcgaaga tatatgattc
    73081 gctgtgaggc caaagtttat ccagcatcgg caccactttg cgcggcacca gaccgtcgag
    73141 atagccatac aatcgcaaaa acggcatggg cacgttttgc agcggctgac ggagatcgac
    73201 cgttttcagg atttccagcc cgccattaag cacgtcaacc tccggcatcg gtaacgccag
    73261 aacggttttc ttcaacgccc gcgcatcctg gcgcgccgtt tcagtcccca tggtttgtaa
    73321 cgccaggaac cgctccactg tacgctgaaa atcatcactg agttgctgct gaaatcccgc
    73381 cagcacgtcc ggttttatcc ccggccactc gtcacgagca ctaaaacaag gtgacgacgc
    73441 cacggtgacc agcgcctgaa cacgctcggg atgggttaac gcaatctggc ttgccaccag
    73501 cccgcccaga ctccagccta accaaatggc tttatcaggt gcctgttgca gcacggcttc
    73561 ggccatatca gcaagtgaca gcgcaccaaa tccccggcta cgcccgaagc cgggcaggtc
    73621 aacaaggtgc agcgtaaaat gcgagctaag ttcctcgtca atgcaacgcc acacttcggc
    73681 attcagtccc catccgtgca gcagcacaag atgaacattc ccctgacctt tggtctgcca
    73741 ccagatgtta ttcatccgct attgttctct tttgacttac aaggatgaac atatgctaac
    73801 agtaccggga ttatgctggc tatgccgaat gccactggcg ttaggtcatt gggggatttg
    73861 ttcggtctgc tcacgcgctg cccgtacaga taaaacgtta tgcccacaat gtggattacc
    73921 cgccacacac tcacatcttc cctgcggtcg ctgcctgcaa aaaccaccgc cctggcaaag
    73981 actggtcacg gttgccgact atgcgccgcc gttaagtccg cttatccacc agcttaaatt
    74041 ttcccggcgc agtgaaatcg ccagcgccct gtcacgtctg ttactattgg aagtcttaca
    74101 cgctcgtcgc accaccgggt tgcaattgcc ggatcgcatc atcagcgttc cgttatggca
    74161 gcggcgtcac tggcgtcggg gatttaatca gagcgatttg ctgtgtcagc cgttatcacg
    74221 ctggttgcac tgccgatggg atagcaaagc cgtcacacga acacgggcca ctgcgaccca
    74281 gcattttctc agtgcccggc tacgcaagcg caacctgaaa aatgcctttc gtcttgaatt
    74341 gcccgtgcaa ggtcgccata tggtgattgt ggatgatgtc gttaccaccg gaagtaccgt
    74401 cgcagagatt gcgcagttgc ttttacgcaa tggtgcggcg actgtccagg tctggtgcct
    74461 ttgtcgaacc ttgtagagcc tcgatgatgg gcgtattata accaactaaa atagtcaact
    74521 attaggccat tactatgatc cgtatttccg atgctgcaca agcgcacttt gccaaactgc
    74581 tggcaaatca ggaagaaggg acacaaatcc gcgtatttgt gattaaccct ggcacgccta
    74641 acgctgaatg tggtgtttct tattgtccgc cggatgccgt ggaagccacc gacactgccc
    74701 tgaaatttga cctgctgacc gcgtatgttg atgagttaag cgcaccatac ctggaagatg
    74761 cagagatcga ctttgttacc gaccagttgg gttctcagtt aacgctgaaa gccccgaacg
    74821 ccaaaatgcg taaagtggca gacgatgcac cgctgatgga gcgcgtggag tatatgctgc
    74881 agtcgcagat caacccacag cttgctggtc acggtggtcg cgtttcgctg atggaaatca
    74941 ccgaagacgg ttacgccatt ctgcaatttg gcggcggctg taacggttgt tccatggtcg
    75001 atgtgacgct gaaagaaggg atcgagaagc agctgctgaa cgaattcccg gagctgaaag
    75061 gtgtgcgcga tctcaccgaa caccagcgcg gcgaacactc ctactactaa gttatcccct
    75121 cttttgtaga ttgcccgatg cgacgctaaa gcgtcatttc gggcctacgt tgaacatgtg
    75181 ccagacgttg gcacagcatt gctttggcaa atccctccct tcgtttcccc gcgataatat
    75241 gaccaacctc tcataattta aatttacccc gctctggtga ttctcaaacg ccagatgtta
    75301 cccgtatcat tcacatgggt accaaacata ctcctgacat ctgactacaa taattagttt
    75361 tagtgggtat cagtcgtggt gccgcaatat ctctgttccc gattgggata attagagttt
    75421 gtcgtcagaa aattgacgtt acccataaca aatgaaaggc caggtaaatc atgccattag
    75481 tcattgttgc tatcggtgta atcttgttgt tgctcctgat gatccgcttc aaaatgaacg
    75541 gcttcatcgc tctcgtcctc gtggcgcttg ctgttggatt aatgcaagga atgccgctgg
    75601 ataaagttat tggctccatc aaagccggtg tcggcgggac gctcggtagc cttgccctga
    75661 tcatgggttt tggcgcaatg ctgggcaaaa tgctggcaga ctgcggtggc gcacaacgta
    75721 tcgccaccac gctgattgcc aaatttggta aaaagcacat ccagtgggcg gtggtgttaa
    75781 ccggttttac cgttggtttt gccctgttct atgaagtggg cttcgtgctg atgctgcctc
    75841 tggtgtttac catcgcggct tccgcgaata ttccactgct ttatgttggt gtaccaatgg
    75901 cggctgcact gtctgtgacc cacggcttcc tgccaccgca tccgggcccg actgcgattg
    75961 ccaccatttt caatgccgat atgggtaaaa ccctgctgta cggtactatt ctggcaatcc
    76021 cgaccgtgat tctcgccggt ccggtttacg ctcgcgtgtt gaaaggtatc gataagccaa
    76081 tcccggaagg tctctacagc gcgaaaacct tcagcgaaga agagatgccg agctttggcg
    76141 tcagcgtctg gacctctctg gtgccggtag tactgatggc gatgcgtgcg attgccgaaa
    76201 tgatcctgcc gaaaggtcac gctttcctgc cggtagcgga gttcctcggt gacccggtaa
    76261 tggctacgct gattgccgtg ctgattgcca tgttcacctt tggtctgaac cgtggtcgtt
    76321 caatggatca gattaacgac acgctggttt cttccatcaa aatcattgcg atgatgctgt
    76381 tgatcatcgg tggtggcggt gcgttcaagc aggtgctggt agacagcggc gtggacaaat
    76441 acattgcttc catgatgcac gaaaccaaca tttctccgct gctgatggcc tggtcgattg
    76501 ctgccgtact gcgtatcgcg ctgggttccg caaccgttgc ggcaatcact gcgggtggta
    76561 tcgcggcacc gctgattgca acgacgggtg ttagcccgga gctgatggtt attgcggtgg
    76621 gttccggtag tgtgattttc tctcatgtga acgatccggg cttctggctg ttcaaagagt
    76681 actttaacct gactatcggc gagaccatca aatcctggtc gatgctggaa accattatct
    76741 cggtgtgcgg tctggtaggc tgtctgctgc tgaatatggt gatttgataa cactgactgc
    76801 cggatgcatc gcatccggca tcaaccgcac tctacttctt cttcgctgca gctctgcgcc
    76861 gtctgtccaa atccttcagc aacttgttca cgccatcatc ggcaaacatc gactcaagcg
    76921 ttgcggaaag cttgcgtcgc cagtttttat actggtaact ggtgccagga atattcaccg
    76981 gttcggccat atccagccag tcttccggct gtagtcctaa cagagcactg ttactgtcgg
    77041 caatgtagcg ctgcaaacca cggttcagcg tcggcgtcat cgacatcaac gatgccttat
    77101 gcccggcacg ttttggcaga caaccatatt tatgcagtgc atccagcagc ccttgcttcg
    77161 ccagttcgcg atcctgatac agaccgcgca gtaccacttc atccggatac agccccaggg
    77221 ttttgcccag cgttagatcc ccgctctccc agtaaccgcg tagcgtaggc aggtcatgtg
    77281 tcgccgcaac cgccatcgac tgctccggat acgctttcgg tgcacggaac gtcttctcgt
    77341 ggtcgttttc gaaatagagc actttgtagg agtacacacc gctgctgcgc agcttaccga
    77401 caatctctac cggtacggta ccgagatctt caccaatcac catacagcga tgacgtttac
    77461 tttcgagtgc cagaatcgag agcagatcat ccaccggata gtgaacatac gcgccctgat
    77521 ctgccgtctc gccatacggt atccaccaca aacgcagcat cgacatcaca tggtcaattc
    77581 gtaatgcgcc gcagttttgc atattggcac gcaacagctc gataaacggt tcataggcac
    77641 gcgcggtgat gatatgcggg tccattggcg gtaatcccca gttctgcccc aacgggccga
    77701 ggatatccgg cggcgcgcca accgacgctt tcaggcaata tagttcacgg tcacaccagg
    77761 tttccgcccc accttccgct acgccaaccg ccagatcacg atacaagcca atcggcattt
    77821 catagccctg gcttatctcc cagcaggcgg caaactggct gtaagccagc cactgcaacc
    77881 agagataaaa atcgacgtca tcacgatgtt cttcgcagaa ctgacgcact tctggtgaat
    77941 ccacgttctg atacatctct ggccatgcag gccagcccca gcgcatttcg tcctctttca
    78001 cttgctgggc atgtagcgca tcaaaggctg cctgccagaa caggctgtcg ccctgctctg
    78061 caacaaactg gcgaaacgcg gtcatctgct catgatcacg ttgcgcgaaa cctttccacg
    78121 ccattcgtaa tgctgtcatt tttagggcgg taaccgtgga gtaatcgacc cagtcggcat
    78181 cgcgcgcctg ttgcagcgtc tgttgcgtgg tcggcaactg ccaccaggcc tgagcctctt
    78241 cgctaagatg gaaatcttca acggcgttaa cgtcgatata aatcacattc agccaacggc
    78301 gagaagacgg gctgtatggg ctggcactct ccggatttgc cggatagagc gcatgaatcg
    78361 ggttcaggcc gatgaacgac ccgccacgtt ttgccacatc caccagcatc gctttgagat
    78421 cgccaaaatc cccaataccc cagttttttt ccgatcgcag cgtataaagc tgaacgcagg
    78481 caccccacag cttttgttta ttcagcaacg cctgcggttc gtaacagcgt ttcggggcga
    78541 caatcacccg gcaatgcgcg cgctggtcgt cctgggtgag tgtcagcgtg tgataacctt
    78601 ccggcagctt cgtcggtaga ttgaacgctt tgccccccgt tacatggcct ttgtactgtg
    78661 ttccttcttc ggtggtcagc agccagctat attcgccgct gccctccacc accatcggca
    78721 tttttttgcc gctggtataa accatgacat tcgggactgg cgttaccgcc actttcgtgg
    78781 cggtacgttg atgcatcgcg tcaagcaaac gccgtttggt ttcggcgcta atcgactgcg
    78841 gtttaccgta ggcattgatg taattggggc taatccccgc cgccagcgcg gcattatcca
    78901 gacgtttgct ttccatcgag cttccttagc gttttgcctg ccagatacga gcctgataat
    78961 cgcgaataga gcgatccgag ctaaacatac cgcagcgggc ggtattgagg atcgccgcgc
    79021 gagtccaggc ctcctggtcg cggtacagca catccacctg cttttgtgcc tcaacatagg
    79081 ctgcgaaatc cgccatcacc agatacggat cgccgccttg tttgccgata ctgtgcagca
    79141 tctggtcgaa ggcatgctta tcgccgtcgc tgtatttacc gctttccagc tctttcaata
    79201 ctgcgtccag caccttatct ttcttccgcc atttcaccgg gtcgtagcct ttggccagaa
    79261 tagccttcac ttgttccacg gtatgaccaa aaataaagat attttcttca ccgactttct
    79321 cggcgatttc aacgttcgca ccatccagcg taccgacagt aagcgcacca ttgagcgcca
    79381 gtttcatatt gccggtaccg gaagcttctt tacctgcagt cgaaatttgt tcggagatat
    79441 ccgccgccgg gatcagtttt tccgccgccg aaacgcaata atccggcagg aacaccacct
    79501 tcaacttatc gccaaccagt ggatcgttgt tgatcacgtc agccactttg ttgatcgcaa
    79561 agataatatt cttcgccagg tagtagcccg gtgccgcttt cgcgccgaag aggaagacgc
    79621 gcggtacgcg atcagcctgc gggttttcac gaatttcttt gtacaacgcc agaatatgca
    79681 gcagattcag gtgctggcgt ttgtactcat gcagacgttt gatctgaata tcgaaaatcg
    79741 cctgtggatt gatctcaata ccagtacgaa ctttcacaaa ctccgccaga cggactttat
    79801 tcgcctgctt gatctcgcga tattgctgac ggaatttcgc atcatcagcg aatttttcca
    79861 gattgatcag ctgatcgaga tcgttagccc actctttttg cagtgattta tccaacagag
    79921 ccgccagtgc agggttgcac tgtttgatcc agcgacgtgg ggtaataccg ttggtgacgt
    79981 tatggaattt gttcggccat agctggtgat attccgggaa cagatctttc accaccagat
    80041 ccgagtgcag cgccgcaaca ccgttcaccg cgaaaccgcc aaccacacac aggttcgcca
    80101 tatgcacttg tttatcgtgc accaccgcca gtttggccca cactttttca tcgcccggcc
    80161 aggttttctc caccagcgtt ttaaagcgag tattaatttc gttaataatc tgcatatggc
    80221 gcggcagtaa gcctttcacc agtttcacat cccagcgttc cagcgcttct ggcatcaggg
    80281 tatggttggt gtaagcgaaa gttttgctgg taatggccca ggcgtcatcc cagctcatct
    80341 ggtgctcatc gatcagcacg cgcagcagtt ctggaatcgc gatagttggg tgggtatcgt
    80401 tcagctgaat aacttcgtaa tccgccagtt cgtgcagttt acgccccgcc agatgatggc
    80461 gacgcaaaat atccgctacc gaacaggcac actggaagta ctgctgcatc aagcgcagct
    80521 ttttaccggc agtatggttg tcgtttggat agagaacttt ggtcagtttt tccgcattga
    80581 tgccctgctg ttcggcacgc aggaaatcac cgtcgttaaa tttagtcaga tcaaacggat
    80641 gcgcgtgcgt cgcctgccac agacgcagcg gctgcgccac gccattacga tagccgacaa
    80701 cggggagatc ccacgcttga ccggtaatgg taaactccgg ctcccagcgt ccgtctttcg
    80761 tcactttacc gccaatccct acctgcacat ccagtgcttc gttgtggcgg aaccacgggt
    80821 agttactgcg gtgccagtca tccggcgctt caacctgttt gccatcgaca aaagactggc
    80881 ggaacaaacc atattgatag ttcagaccgt aacccgtcgc agactgaccg acagttgcca
    80941 ttgagtcgag gaagcacgcc gccagacgtc ccagaccacc gttacccagc gccgggtcga
    81001 tctcttcttc cagcaggtcc gtcagattga tgtcataagc cttcaacgaa tcctgtacat
    81061 cctgatacca gccgagattc aacaggttgt tgcccgtcag gcgaccaatc aaaaactcca
    81121 ttgagatgta gttaacatgt cgctgattcg ccaccggctt ggcgaatggc tgagcacgca
    81181 gcatttcggc cagtgcttca ctcactgcta gccaccactg gcgaggagtc atttcagccg
    81241 cagaatttaa gccataacgc tgccactgac gtgaaagcgc ttcctgaaat tgcttatcgt
    81301 taaaaatagg ttgtgacata ggagttccac ttttcttaga ttttcaacac aacgttatcg
    81361 ctagtttgcc aggctcgatg ttgaccttcc tcatcctgcg ggggattagg cagggaggag
    81421 ttgcggggat gagcaaggaa atgtgatctc aaccacttaa agctagtgca aaccacagga
    81481 ttagcagcaa atcaatgcaa tacagcgcag aaaatctgta tctaagtgca aaaaatggcc
    81541 gttgcgtatt ttcaaaaagc ggaaggtaac tctataaatt aagtaaagga gtgaaacagt
    81601 ttcataagta aaatatccag tgtgctccat ctcattctta atagatttat taagatcatc
    81661 tttttagatg gcactttcat caggaatgaa gaagaaaccc ttgcttaaat gaatctgatg
    81721 aacataaggg aaaccagtat tcacgctgga tcagcgtcgt tttaggtgag ttgttaataa
    81781 agatttggaa ttgtgacaca gtgcaaattc agacacataa aaaaacgtca tcgcttgcat
    81841 tagaaaggtt tctggccgac cttataacca ttaattacga agcgcaaaaa aaataatatt
    81901 tcctcatttt ccacagtgaa gtgattaact atgctgattc cgtcaaaact aagtcgtccg
    81961 gttcgactcg accataccgt ggttcgtgag cgcctgctgg ctaaactttc cggcgcgaac
    82021 aacttccggc tggcgctgat cacgagtcct gcgggctacg gaaagaccac cctcatttcc
    82081 cagtgggcgg caggcaaaaa cgatatcggc tggtactcgc tggatgaagg tgataaccag
    82141 caagagcgtt tcgccagcta tctcattgcc gccgtgcagc aggcaaccaa cggtcactgt
    82201 gcgatatgtg agacgatggc gcaaaaacgg caatatgcca gcctgacgtc actcttcgcc
    82261 cagcttttca ttgagctggc ggaatggcat agcccacttt atctggtcat cgatgactat
    82321 catctgatca ctaatccagt gatccacgag tcaatgcgct tctttattcg ccatcaacca
    82381 gaaaatctca ccctggtggt gttgtcacgc aaccttccgc aactgggcat tgccaatctg
    82441 cgtgttcgtg atcaactgct ggaaattggc agtcagcaac tggcatttac ccatcaggaa
    82501 gcgaagcagt tttttgattg ccgtctgtca tcgccgattg aagctgcaga aagcagtcgg
    82561 atttgcgatg acgtttccgg ttgggcgacg gcactacagc taatcgccct ctccgcccgg
    82621 cagaataccc actcagccca taagtcggca cgccgcctgg cgggaatcaa tgccagccat
    82681 ctttcggatt atctggtcga tgaggttttg gataacgtcg atctcgcaac gcgccatttt
    82741 ctgttgaaaa gcgccatttt gcgctcaatg aacgatgccc tcatcacccg tgtgaccggc
    82801 gaagaaaacg ggcaaatgcg tctcgaagag attgagcgtc aggggctgtt tttacagcgg
    82861 atggatgata ccggcgagtg gttctgctat cacccgctgt ttggcaactt cctgcgccag
    82921 cgctgccagt gggaactggc ggcggagctg ccggaaatcc accgtgccgc cgcagaaagc
    82981 tggatggccc agggatttcc cagcgaagcg attcatcatg cgctggcggc aggcgatgcg
    83041 ctgatgctgc gcgatattct gcttaatcac gcctggagtt tgttcaacca tagcgaactg
    83101 tcgctgctgg aagagtcgct taaggccctg ccgtgggaca gtttgctgga aaatccgcag
    83161 ttagtgttat tgcaggcgtg gctaatgcaa agccaacatc gctatggcga agttaacacc
    83221 ctgctagccc gtgctgaaca tgaaatcaag gacatcagag aaggcaccat gcacgcagaa
    83281 tttaacgctc tgcgcgccca ggtggcgatt aacgatggta atccggatga agcggaacgg
    83341 ctggcaaaac tggcactgga agagctgccg ccgggctggt tctatagccg cattgtggca
    83401 acctcggtgc tgggtgaagt gctgcactgc aaaggcgaat tgacccgctc actggcgcta
    83461 atgcagcaaa ccgaacagat ggcacgccag cacgacgtct ggcactacgc cttatggagt
    83521 ttaatccagc aaagtgaaat tctgtttgcc caagggttcc tgcaaaccgc gtgggaaaca
    83581 caggaaaaag cgttccagct gatcaacgag cagcatctgg aacagctgcc gatgcatgag
    83641 tttctggtgc gcatccgagc acaactgtta tgggcctggg cacggctgga tgaagccgaa
    83701 gcgtcggcgc gtagcgggat tgaagtcttg tcgtcttatc agccacagca acagcttcag
    83761 tgcctggcaa tgttgattca atgctcgctg gcccgtggtg atttagataa cgcccgtagc
    83821 cagctgaacc gtctggaaaa cctgctgggg aatggcaaat atcacagcga ctggatctct
    83881 aacgccaaca aagtccgggt gatttactgg caaatgaccg gcgataaagc cgccgctgcc
    83941 aactggttgc gtcatacggc taaaccggag tttgcgaaca accacttcct gcaaggtcaa
    84001 tggcgcaaca ttgcccgcgc acaaatcttg ctgggcgagt ttgaacctgc ggaaattgtt
    84061 ctcgaagaac tcaatgaaaa tgcccgcagt ctgcggttga tgagcgatct caaccgtaac
    84121 ctgttgctgc ttaatcaact gtactggcag gccggacgta aaagtgacgc ccagcgcgtg
    84181 ttgctggacg cattaaaact ggcgaatcgc accggattta tcagccattt tgtcatcgaa
    84241 ggcgaagcga tggcgcaaca actgcgccag ctgattcaac tcaatacgct gccggaactg
    84301 gaacagcatc gcgcacagcg tattctgcga gaaatcaatc aacatcatcg gcataaattc
    84361 gcccatttcg atgagaattt cgttgaacgt ctgctaaatc atccggaagt gccagaactg
    84421 atccgcacca gcccgttgac ccaacgtgaa tggcaggtcc tggggctgat ttactccggt
    84481 tacagcaatg aacaaattgc gggcgaactg gaagtggcgg caaccaccat caagacgcat
    84541 atccgcaatc tgtaccaaaa actcggcgtc gcccaccgtc aggctgccgt gcagcacgcg
    84601 cagaaactgc tgaagatgat gggttatggg gtgtgagttt agccggataa tgcattggat
    84661 ccggtttaca tctttacatc attcaatact cacccgcgtt acgccatctg tttctatcaa
    84721 accaaaccgc accggcaaga aacgctccac caccgcgata ttggtcagca gatggcatga
    84781 aggatgggcg accttaaatt ctcccgcgcc cgccagcgcc atcggcagta ccagttggtc
    84841 ggcgagatat tcccccaccg ccgctgggct tgccaggtag cgtttcacct ctttcactaa
    84901 ctgcgcggct accacctcgg cactgacgcg cttttcaccg acgacgaaaa agcgttcagt
    84961 gatattttca ctttcgactt ccagcgagac ggtattaccc ggcccctggt cgcgcggcag
    85021 gttatgaata ttctgttcat gcagggaaaa actccccgcc agtgtagcga tttcacgctc
    85081 agcaacatgg cgcggcacac cagctaatag aacctctcca cgcatctgca caatgttccc
    85141 gcgctcgcca agttgcaagg tgttaaacga tgccacgggc gagacttccg ttgccaccac
    85201 gccgcctccg gcaggataaa aaccgtgacg taacagcgtg gtttgctgat gaattcctat
    85261 tttcgccagc agcggctcca gcacccggcg gataaaatcc gcaggcgggg ccgacgggtt
    85321 atcggtgcct ccgctcactt caacacgcga aggtccatcg gcaaaccaca gcgcgggcag
    85381 caccgtttgc agcaccagcg tacagcttcc ggcactaccg atagcaaagc ggtactcgcc
    85441 gccgcgcacg atgccaggcc ggaagaccag acgctgcgac cccagctccg cgccttccac
    85501 cgttgcccta caaatttccg cagccgcttt taccgcggtc agatgctggc gcaacagccc
    85561 cggtttcgcc cgcccggcac gaatgctggt gatggtaaat ggctggccgg ttatcatcga
    85621 caggctcagc gccgagcgca ggatctgccc gccaccttcg ccctgtgcgc catccagcgc
    85681 aatcatcctt ttcatcattt atccttttac gcacaccacc tgacgcaggg tatagataac
    85741 ttccaccaga tcgctttgtg ccgccatcac cgcatcaata tctttatacg ccatcgggat
    85801 ttcgtcgatc acttcggcat ctttacggca ttccacatgc gcggtggcac gaatttgatc
    85861 ttccacgctg aacagttttt tcgctttagt acggctcatt acccgcccgg caccgtggct
    85921 gcacgaacag aaagattctt catttcccag cccacggacg ataaagcttt ttgctcccat
    85981 cgaccctgga ataattccat attgaccagc acgcgcagac accgcgcctt tacgcgtcac
    86041 gtagatctct tcaccaaagt gctgttcttt ttgcacatag ttgtggtgac agttgatctc
    86101 ttccatcgcc agcgtttgtg gctgtctgac cgttttctgc gtaatgctct gcaatgccgt
    86161 taccacgttt tccatcatcg catcgcggtt aaggctggca aaaagctgcg cccaggccac
    86221 ggctttcagg taatcatcaa agtattccgt accttccata aagtacgcca gatcacgcga
    86281 cggcaacgtc tcaagcgttt cctgcatctc tttttgtgcc agatcgataa agtaagtccc
    86341 gatggcgtta ccaattccgc gtgaaccgga gtgcagcata atccacacct ggtccgactc
    86401 atcaaggcag atttcaataa agtggttacc ggttcccagc gttcccaggt gtttatagtt
    86461 attggtattc aggaaacggg gatatttttg cgttaaccac tgataaccgg cttcaagctc
    86521 agcccatttc gcatcgacgt taacaggcgg gttttcccat gcgcctttat cacgtttaca
    86581 acggccagtg gtacgcccgt gcggcacggc catttcaatc gcctgacgca gctctgccag
    86641 gttttcaggc aggtcttccg ccgttaacgc ggtacgcagc gcgttcattc cacagccaat
    86701 atccacgccc accgccgccg gaataatcgc ccctttggtc gggatcacgc taccaatggt
    86761 ggaaccttta cccaggtgta catcaggcat taccgcaata tgtttgaaaa taaacggcat
    86821 cttcgccgta ttaataagtt gctgacgcgc atcggcttct accggcacgc ctttggtcca
    86881 catttttacc ggggcatttt cagtggtcag taattcgtaa ttcattttgt ttttctcttt
    86941 tcgttgtttg ctgtcgtgat aattgcaacc gtcgtgccag aaaattaaat aagcagatta
    87001 attttttaat tcattgtttt taaataggtt aaatctttac gtccgtaaac ggagattttc
    87061 cacaaaacca attcaccgat aatgaaatat cgtcttttat aaggatatct aagatgcgta
    87121 aaacagtggc ttttggcttt gtcggtaccg tgctggatta tgccggacgc ggcagtcagc
    87181 gctggtcgaa atggcgtccg acgctttgtt tatgccagca agaatcgtta gtcatcgatc
    87241 ggctggaatt gttgcacgac acccgctcgc gctcgctatt cgaaacgctt aaacgcgata
    87301 tcgccagcgt ttcgccagaa acagaagtcg tgggcgttga gattgaactg cataacccgt
    87361 gggatttcga agaggtttac gcctgcctgc atgatttcgc ccgtggttac gagtttcagc
    87421 cagaaaaaga agactattta attcacatca ccaccggcac ccacgtcgcg cagatttgct
    87481 ggtttctgct ggcggaagcg cgttacctgc ccgcccggct gatacaatct tcacctccgc
    87541 gcaaaaaaga acagccgcgc ggcgcaggtg aagtgacgat tatcgatctc gatttaagcc
    87601 gttataacgc catcgccagc cgctttgccg aggaacgcca gcaaacgctt gattttctta
    87661 agtccggcat tgccacgcgt aacccccact tcaaccgcat gattgagcag atcgaaaaag
    87721 tggcgatcaa atcccgcgcg ccgattctgc ttaacggtcc aaccggcgcg ggcaagtcat
    87781 ttctggcgcg acgcatcttc gagttaaaac aggcgcggca tcagtttagc ggcgcgtttg
    87841 tggaagtgaa ctgcgccacc ctgcgcggcg ataccgccat gtcgacgctg tttggtcatg
    87901 taaaaggcgc gtttaccggg gcgcgggaat ctcgtgaagg tttattacgc agcgccaacg
    87961 gcggaatgtt gtttcttgat gagattggcg aactgggcgc agacgaacag gcaatgctgc
    88021 taaaagccat tgaagagaaa accttttacc cgtttggcag cgatcgccag gtgagcagtg
    88081 tttttcagct tatctccgga acggtgcgcg atttgcgcca gctggttgcc gaaggcaaat
    88141 ttcgcgaaga tctgtacgcg cggatcaatc tctggacctt caccctgccg ggtctacgcc
    88201 agcgccagga agatattgaa ccgaaccttg attatgaagt ggagcgccac gccacactca
    88261 ctggcgacag cgtgcgtttt aacaccgaag cgcggcgcgc ctggttggct tttgcgacct
    88321 ctccccaggc aacatggcgc ggtaactttc gcgaactttc tgccagcgtc acgcggatgg
    88381 ccacctttgc cactagcgga cgcatcactc tggacgtggt tgaagatgag ataaaccgtc
    88441 tgcgctataa ctggcaggag agccgcccct ccgcgcttac ggcgttgctg ggcgcagagg
    88501 cagaaaacat cgaccttttt gacaggctgc aactggaaca cgtgatagct ctctgtcgcc
    88561 aggcaaagtc gctttccgct gccggacgcc tgctttttga tgtttcgcgc cagggcaaag
    88621 ccagcgtcaa tgacgcggat cggctacgca aatacctggc gcgttttggt ctgacgtggg
    88681 aagccgtgca ggatcagcac agctccagtt gaatatgatg gtccgtcagc acctgcatta
    88741 cgcttactgg cggcggggcg tcggtgtaga cggcatctac catgctgatg ctgcccatat
    88801 tgaccatcgc gttacggcca aatttcgagt gatcgacaac cagcataacg tggcgcgagt
    88861 tctcaataat ggcgcgcttg gtgcgaactt cgtggtaatc gaactccagc agcgagccgt
    88921 cgctatcgat gccgcttatc cccagaatgc cgaaatcaag gcggaactgg gagataaaat
    88981 cgagcgtcgc ttcgccaatg atcccgccat cgcggctgcg taattcgcca ccggcgagaa
    89041 taatgcggaa atcttctttt accatcaacg tgttagcaac attgagattg ttggtgacaa
    89101 tacgcaaatt gctgtgatta agcagcgcgt gcgccaccgc ttccggcgtg gtgccgatat
    89161 cgataaacag tgtcgagccg ttggggattt gctccgccac tttgcgggca atcctctctt
    89221 tttcttcggt ctgggtggct ttgcgatcgt gccacggcgt gttaaccgaa ctggaaggca
    89281 gcgccgcacc gccatggtga cgcaggatca ggttttgctc cgccagctca ttgaggtcgc
    89341 ggcgaatagt ctgcgggctg acggagaaat gctctaccag ctcttcagta ctgacataac
    89401 cctgctgttt aaccagttcg ataataccgt tgtgacgttg tgtttgtttc atttataaat
    89461 ccctggaatt attttcgttt tcgcgcattg agcgaatcaa caaaagccat cgctaaaccc
    89521 acggctaacc cggcgatgtg tgctccgttc gccatcgaca tcccaaacaa atcaaaccat
    89581 ccggcgacaa tccagatcag cgcaaagata attaacccac gttgcaggta aatgccactt
    89641 tgcggatcgc gttcaccacg tagccagacg tagcccatca gcgcatacac cacgccagaa
    89701 agcccgccaa accacggccc gctgaatttt tgctgcacat agccgcttaa cagggcgcta
    89761 atgagagtaa taacaattag cttaccgcta ccgaggcgtt tttccaccgc accgccgaga
    89821 taccaccacc agagcaggtt aaagaggata tgcatcagcg agaagtgcat taacgcgtgg
    89881 gtgaagtaac gccagaactc aaatttcagt gttggatcga atggccaggc cagccataac
    89941 atcacttcct gatcgccgag aatttgcatg gcgataaaca ccaccacgca ggcgatcatc
    90001 accacccagg ttaccggacc tgcgcgttca cgcaaggcgg caaagaaagg ataacggcga
    90061 taatgcaggc cactgccggt atggcctgcc tgccagctgg ccgccagata acgcggatct
    90121 gccgggtttt cgagaaaacg cgccagctcc gcccgtacgc gctcggcctg ggactcatcc
    90181 gccagccaga catcgctttg gttatgttgt tgaatcgtga ggataacacc ctgcgtcgcc
    90241 atgtaatcaa caaacgcctg cgccacgcgg gggttagcaa aagaggtaat catcaacatc
    90301 gttgctgtcg cttattccac acaaaagggg acagtataaa gcgttacgcg ccgtacgcca
    90361 cctctgcggg aaactgacgt tgccaggctt caaagccgcc gtcaatgcta tagaccacat
    90421 cgtagccctg ttgcagcaga tactgcgccg cgcctttgct gctattgccg tgataacaca
    90481 tcaccatcac cggagtgtca aagtcgttat cacgcataaa cgcgcccagc gtgtcgttgg
    90541 ttaaatggaa agcctgcacc gcatgcccca tagcgaaact ctgtggatcg cgaatatcga
    90601 ccagcaccgc ctctttttcc tgcaacttct ggtgcgcgtc ggcaacgtta atacattcga
    90661 actgatccat gcgtctctct ttctttacaa acaagtgggc aaatttaccg cacagtttac
    90721 gtcgaagcgg cagataaacg ccataatgtt atacatatca ctctaaaatg ttttttcaat
    90781 gttacctaaa gcgcgattct ttgctaatat gttcgataac gaacatttat gagctttaac
    90841 gaaagtgaat gagggcagca tggaaaccaa agatctgatt gtgataggtg gcggcatcaa
    90901 tggtgctggt atcgcggcag acgccgctgg acgcggttta tccgtgctga tgctggaggc
    90961 gcaggatctc gcttgcgcga cctcttccgc cagttcaaaa ctcattcacg gtggcctgcg
    91021 ctaccttgag cactatgaat tccgcctggt cagcgaggcg ctggctgaac gtgaagtgct
    91081 gctgaaaatg gctccgcata tcgccttccc gatgcgtttt cgcctgccac atcgtccgca
    91141 tctgcgcccg gcgtggatga ttcggattgg tctgtttatg tacgatcatc tgggtaaacg
    91201 caccagcctg ccgggatcaa ccggtttgcg ttttggcgca aactcagtgt taaaaccgga
    91261 aattaagcgc ggattcgaat attctgactg ttgggtagac gacgcccgtc tggtactcgc
    91321 caacgcccag atggtggtgc gtaaaggcgg cgaagtgctt actcggactc gcgccacctc
    91381 tgctcgccgc gaaaacggcc tgtggattgt ggaagcggaa gatatcgata ccggcaaaaa
    91441 atatagctgg caagcgcgcg gcctggttaa cgccaccggc ccgtgggtga aacagttctt
    91501 cgacgagggg atgcatctgc cttcgcctta tggcattcgc ctgatcaaag gcagccatat
    91561 tgtggtgccg cgtgtgcata cccagaagca ggcctacatt ctgcaaaacg aagataaacg
    91621 tattgtgttc gtgatcccgt ggatggacga attttccatc atcggcacca ccgacgtaga
    91681 gtataaaggc gatccgaaag cggtgaagat tgaagagagt gaaatcaact atctgctgaa
    91741 agtgtataac gcgcacttta aaaaacagct tagccgtgac gatatcgtct ggacctactc
    91801 cggtgtgcgt ccgctgtgtg atgatgagtc cgactcgccg caggctatta cccgtgatta
    91861 cacccttgat atccatgatg aaaacggcaa agcaccgctg ctgtcggtat tcggcggtaa
    91921 gctgaccacc taccgaaaac tggcagaaca tgcgctggaa aaactgacgc cgtattatca
    91981 gggtattggc ccggcgtgga cgaaagagag cgtgctgccg ggtggtgcca ttgaaggcga
    92041 ccgcgacgat tacgcagctc gtctgcgccg tcgctatcca ttcctgactg aatcgctggc
    92101 gcgtcattac gcacgcactt acggcagcaa cagcgagctg ctgctcggca atgcgggggc
    92161 gataagcgac ctcggggagg atttcggtca tgagttctac gaagcggaac tgaaatacct
    92221 ggtggatcac gaatgggtcc gccgcaccga cgatgccctg tggcgtcgca caaaacaagg
    92281 catgtggctg aatgcggatc aacaatctcg tgtgagtcag tggctggtgg aatatacgca
    92341 gcagaagttg tcgctggcgt cgtaaggatg atgcccggtt gaagtgcaac cgggctattt
    92401 ggattcctta gactattcat tgtaaataat tgaataacgg cccctgagct aaaatcgcca
    92461 aacttaagca cgttacccaa tcgccccact tcttcctctg gtttctattt tttctgcacc
    92521 aatggcaata atatcccaat gcaaaaccaa gctgtgcact aatcgggccg acaaaatcag
    92581 tccaaggctg cggccaaaaa ggggaaaaat tcaggggagg ccagacaaac gtcagaaaga
    92641 aatttcggat attttccagc aacgctgatt tctctggaga aatataaaga atgaaattcg
    92701 agagaattaa ccagaaatag accggcgaaa agaccagcca gcaatgcagt ctgtttttta
    92761 attcaggagg cgttctgcgg gagaattgcc aaccgatgcc agccattaca ctgaaaaaaa
    92821 gtgcatattc aaccattaac tcaagttgta attcctgaag agaaatacgc acaaccagga
    92881 gcggaaagga gaatattatt tctgccagaa aagttaacgt gaatataagt acggctaaga
    92941 caataaccgt cggccatacc aataatggca cgataacaaa accgagaatt acagggggaa
    93001 tataaagccg gaatttaatc atttttattt tcctggtgat tcggatgatg cgtcatacat
    93061 cgcgcataaa cactcatcaa ttatccagtc gtctacccag acctgatgct gtgtgccctg
    93121 ttctggctgc tttggtgggt tctcaatcgc ctgccgcgcg cgttctttca agatggattg
    93181 attgttgaag gcccaggcat tgatttgggt ggtaatgacg ttatcgatat cgtcctggtt
    93241 atctctgata taatcctcac aatatctgtt caataaacag gcaagagaaa cggtcgacca
    93301 aaagccggga actgaattaa tggcatccag caatggcgca agagcgatat cggcacggaa
    93361 aaacatttcc agcatatact gtaattcgac agtttcatcg ccggataccc aatcagtcat
    93421 atactggcag gcaaatcgtt gcaaaatttt ccattcatcc tcacgccaat tttctttact
    93481 ggcaaggttg atacggcgca gagaaaaaac tacgtgaata ttgtcaaaat gcccctgtgc
    93541 aacaaattcc agtaaacgcg gcagaaaata gcggacctca tcgctatttt gcggatcagg
    93601 ccctgggcta ctattccagg cattgattaa ggaatacggg atcgctcgta acgatgtact
    93661 ccgtaatgcc ttttgttcct gctgactcag gcaatattca caacaaacca caaatttctg
    93721 cggcacccga taacgacgaa aggtgtgata aatctgctca attaatgcct gcatggcggg
    93781 gctgggttgc atagttaccc cctcgcccgc tgatcgcgtg taaacggttg atagacaaaa
    93841 cgagcattcg ccgcgttcag gcgaataagg gcgctacgcg aaagggaaaa gctggggcga
    93901 atgcaactat tgcagtctcg acagctttcc tctgcgcaat tttccactga gtaatgacgc
    93961 gtgtagagtt tcagttcggc ctgcttatcg cgaaatccgc gtaaactgtt attgttatga
    94021 aatttccagg catctttaaa gacctgaaag atatagacat cctcaatcca ggagtcacat
    94081 tttttaagcg ggcgctttgc tattatcacc cgctcatccg gatttagcat cgccgtaaat
    94141 tgtacggtga cgtcatttgt cgtgttcagg tcacattgaa catctggtac atcactgata
    94201 taggggtcaa atccaaaatc agcaccacag gcacaaagac ggctaatggt ggcggtatcg
    94261 agggaaaatc ccggccatac attgctggac gttaagccaa tatttaatgt gacattatat
    94321 cgaagcaatc cctcaagacc gtcagcaccg acgaactttt ccccttcatc cagggcctgg
    94381 ttaatgagtt gctgaacaat gccttcatcc cagtatgccg atttgcagtt ggcaatcgta
    94441 atatccacgc ctgtgaaggg atcagtaccg gcaaggcttg caaataatgt attaactaat
    94501 tccattttta ttatccagct ttaaggtagc gtcttataca tcgggacata acctacatct
    94561 tccaccaaac tctgtccctg cggcgttaaa aaccactcca acaatttttg tgtctctgac
    94621 gtcgtatttt cccgcgttac cataaaggca tcgacgatat agggatattt gccgttgcga
    94681 atgttttcgg cagtcggtgc aataccgtta atcgctagca gttttatatt tttatcgtcg
    94741 ttcatttgtg ttgcgtaata acggaaggtg taacctattg cgttgtttgt attacggtat
    94801 tcggcaacga ctttaatcat tccctccatc atacttgcca cttctgtttc ctgcggcgag
    94861 atcatgcgga catttttcat gacctgggat tgcatcaccg tctggctacc agagtcttcc
    94921 gggcgttgcc aggtctggat ctcctgatcg ttaccgccaa ccgtgcgcca gttggtaatt
    94981 gcaccactga agatgtcacg cacttgttgt tcggtcaggg aattaaccgg gttatctgca
    95041 ttgacgatga aaacaaacgc ttcacgggca aaaggcgtgt aaatcaaagt gacgcccgat
    95101 tcctccgcgc gttttttctg cccaccggaa ggttgagcca caaagataat atcggcatta
    95161 cctttaacaa tcttgttata tgcttcggga gtacgagagt tcgccagata ttcccattcg
    95221 tgaaaatctt ccggcaaaac gcttagtgca taaaaggcag aggcataaat ggggtacgcc
    95281 gccgttgcgc catcaagtcg cggccagttt tgcgtgaact gaatttgcgg tttaccacgc
    95341 agtggtgtca gttgattatt gagtttatcg ggtcgccagg cccaggtatc aatattttca
    95401 cgcacaccga cgccgggatt aagctgttta tataaataag cctggtaacc ggcgacaaaa
    95461 ccaagcatga gaaggataaa caagagagaa ttacggcaac gtaacccgga cgtgcccgtt
    95521 aaaggatatc tggtcggcca gccgtacccc agcgaaaaac tgatatgcgc gccaacaggt
    95581 ataatgacta accaccagta ctcaccaccg actaatgagg ctaacaaaac gcccagccag
    95641 gggagcataa gatcagccaa ccaacccgct cccatctggt gaaattgata atctgccaga
    95701 tgcagcgcga ttatccagac ccccagggtt aataatgcgg gtactaaaaa aagacattgt
    95761 cgccagacgg ctatttctct tttttctggt gcactatcgt ccgcccacac tcgccccgag
    95821 aaaaatagca ttaatgcgcc cagcgccagc ataaaaatgt tgagcagaag gtaaattgtt
    95881 ggcgtgataa agatattaca aacttcaata ataccggcaa gtccgacacc cagcatggca
    95941 ataaccgccg ccaaaaactg cgccagaatg gggatgccga aaaaagtcat taccagcgag
    96001 gtcaaaatcc attttctgtt ttgcattatt ctttccattc tttctgaatg gcgaaattat
    96061 actccccgag tccccttgcc ccttctggac acttttccga aatgatggcg aaaaaaacgg
    96121 gaccctttgg ccccgttcta tttattagtg aaattacaat ctcaccggat caatatgcca
    96181 gatatgatcg gcgtactctt tgatagtacg gtcagaagag aagtagccca tattggcaat
    96241 gttcagcatc gcttttgcgg tccactcttc ctgaagctcg tagagttcat cgactttatc
    96301 ctgacaatcg acatagctgc gataatccgc cagtacctgg tagtgatcgc cgaagttgat
    96361 cagcgaatca accagatcgc gatagcgacc cggatcttcc ggactgaata caccgctgcc
    96421 gatttgcgtc agcacctgat gcagctcctc atctttctcg tagtattcac gcggtttgta
    96481 gccctgacga cgcagttctt ccacttcttc cgctgtgtta ccaaagataa agatattgtc
    96541 agcaccgaca tgatccagca tctcgacatt cgcaccgtcc aacgtaccga tagtcagcgc
    96601 accgttaagc gcaaacttca tgttactggt gccggaagct tccgtccccg ccagcgaaat
    96661 ctgttcagac agatcggccg ccggaatgat caactgcgcc aggctaacgc tgtagttcgg
    96721 gatgaacacg actttcagct tgtcgccaat ctgcggatcg ttgttgatca ctttcgctac
    96781 gtcattgatc aaatgaataa tgtgcttcgc catgtaatag gccgaagccg ccttaccgcc
    96841 aaaaatattc acgcgcggta cccacttcgc atccgggtcg gccttgatgc ggttatagcg
    96901 ggtaatcaca tgcaacacat tcatcaattg acgtttgtat tcgtgaatac gtttgatttg
    96961 tacatcgaac aacgcctttg gattcaccac cacattcagc tgctgggcga tatactctgc
    97021 cagacgcttt ttgttctcca gcttcgcctg atgcacagcg tgattaacca ttgggaaatc
    97081 acagtgttgt tgcagctcat taagcaggct aaggtcggtg cgccagttac ggcccaggtg
    97141 ttcgtccagc acggctgaaa gcgatgggtt cgctaccgct agccagcgac gcggcgtcac
    97201 accgttggtg acgttggtga aacgacccgg gaagattttc gcaaagtcgg caaacaacga
    97261 ttgcaccatc agattagagt gcagttccga tacaccgtta actttgtggc tcacaacaac
    97321 cgccagccag gccatacgca cacgacgacc gttggattca tcaatgatcg acgcccgtcc
    97381 cagcagatcg gtatcgttcg gatactgttc ctgcaaggtt ttcaggaaat agtcgttgat
    97441 ttcaaagatg atctgcaggt gacgcggcag aattttaccc agcatatcaa ccggccaggt
    97501 ttccagcgcc tcgctcatca gcgtgtggtt agtgtaggag aagacctgac aacacacctc
    97561 aaacgcgtcg tcccagctaa attggtgctc atcgatcagc agacgcatca tctcaggaat
    97621 cgacagtacc ggatgggtat cattgagatg aatcgcgatt ttatccgcca ggttatcgta
    97681 ggttttatgc aactgataat ggcggcttaa aatgtcctga atggtcgagg aaaccaggaa
    97741 gtattcctga cgcaggcgca gctcacgccc ggagtaggtg gagtcatccg gatacagtac
    97801 gcgagatacg ttctcggagt ggtttttatc ttccactgcc gcgaagtagt caccctggtt
    97861 gaatttaccg aggttaattt cgctactggc ttgggcactc cacaaacgca acgtgttggt
    97921 cgcgtcggta tcgtaaccag ggattatctg atcgtaagcg actcccagaa tctcttcggt
    97981 ttcaatccag cgcgtttttt taccttcctg ctgaatgcga ccaccaaaac ggactttata
    98041 gcgcgtgttg tggcgtttga attcccacgg gttaccgtat tccagccagt agtctggcga
    98101 ctctttctgg ctaccgttaa cgatgttctg cttgaacata ccgtagtcat agcggatgcc
    98161 gtaaccgcgc cccggcaacc ctaacgtcgc cagagaatca aggaagcaag ccgccagacg
    98221 tcccaggcca ccgttaccga ggcctgggtc attttcttca tcaatcagct cttcgagatt
    98281 taaccccatc gcttccagtg cgccctgtac atcttcgtaa attcctagcg acaacatggc
    98341 gttggagagc gtacggccaa tcaaaaactc catcgacagg tagtaaacct gacgagtttc
    98401 ttgcgacaac tgggcacggt ttgaacgtaa ccagcgctcc acgagacgat cgcgcacagc
    98461 aaataacgtt gcgttcagcc attcatgttt attggcgacg accgggtcct ttccaatcgt
    98521 aaacatcagc ttgtaagcga tagagtgctt aagagcttct acgctaagcg tgggcgatga
    98581 atatgtaaac ggagcattca tataggcgtt tcctgaaaac tatttcaagc gatagtaaag
    98641 ctcacggtac gacttcgccg cgacctgcca gctaaaatcc attgccatag cctgacgttg
    98701 cacaaaccgc cacagtgaag gacgggacca cagtacaaaa gcacgccgaa tagcccgtaa
    98761 cagcgaccag gcattactat cttcaaagac aaacccactg gcgacgccat ctgcaaggtt
    98821 ctcaagagaa cagtcagaaa ccgtatcagc aagcccaccg gtgcgccgca ctaacggcag
    98881 cgtaccgtac ttcaatccat aaagttgcgt taagccgcac ggttcaaaac ggctgggcac
    98941 cagaatgacg tccgcgccgc ccataatgcg atgcgaaaat gcttcgtgat agccaatctg
    99001 aacgcccacc tgaccggggt attccgctgc cgccgcaagg aaaccttcct gcagcaccgg
    99061 atcgcccgcg ccgagtagcg ccagctgccc gccctgctcc agaagacccg gtaaggcttc
    99121 cagcaccagg tcgagacctt tctggctggt cagacggctc accactgcaa aaagcggcac
    99181 tttatcgtca accttaagcc ccattgcgat ttgtaactgg cgcttatttt ccgctttatc
    99241 ttccaacgta tcgcgggtgt aacgcgaggc caacagtaag tccgtctctg gactccagat
    99301 tttctcgtcc acgccgttca gtacgccgga aagacgccct tcacggtgac gctgttgcaa
    99361 cagaccttcc ataccgtagg caaactgcgg ttcggtgatc tcgcgagcgt aggttggact
    99421 gaccgccgta atgtgatcgg catagtacag accggccttc aggaaagaga tttgtccgtt
    99481 gaattccagc ccatgaatat taaagaatga ccatggcaat tggatgtcat tcatgtgatg
    99541 tgcataaaac atgccttgat aggccaagtt gtgcacagta aacaccgact tcgccggacg
    99601 cccgcgcgcc gccagatacg caggcgcaag gcctgcatgc cagtcgtgcg catgcaccac
    99661 atcaggacgc cagaatgggt caagcccgct ggccatttct gccccaaccc accccagcag
    99721 cgcaaaacgc aatacgttgt cggtataggc aaataagttg gtatcgtgat acgggcttcc
    99781 cggacgatca tagagatgcg gcgcgtcaat caggtatatg ccaaccccgt tgtaatgacc
    99841 gaacaacagc gtgatatgtc cggcgaaggt atcacgacgg gatactacct gcgcatcggt
    99901 cacgccacgg cgaatatcgg gaaatgcagg caacagtacg cgagcgtcaa cgccgtctgc
    99961 gatttgtgct gcgggtaatg ccccaataac atcagccaga ccgccggttt taagcagcgg
   100021 gaacatctct gaacatacat gtaaaacctg cattatcgct cctgtttatg ccctaacttc
   100081 cgtagcattt cgcgcgttac cagcacgatg ccttcttctg aacgatagaa acgacgtgca
   100141 tcttcctctg cgttttcacc aatcaccatg ccttccggaa taacacaagc acgatcgatg
   100201 acgcagcggc gcagacggca cgagcgacct acccatactt ccggtaacaa tacggcggaa
   100261 tcaatgttgc agaatgaatt cacgcgaacg cgcgagaaca gaacggactg caccaccacc
   100321 gaaccggaga tcacacaacc gccggatacc agtgagttaa gggtcatccc gtggctaccg
   100381 gagcgatcct gcacgaattt cgctggcggt aatgattcat tgtaggtgcg aattggccaa
   100441 ttgcgatcgt acatatccag ttccggcacc acagaggcca gatcgagatt cgctttccag
   100501 taagcttcca gcgtacccac atcgcgccag tacggctcgg catccgggtc ggattgtacg
   100561 caagagagcg ggaacgggtg cgcataggcc agaccggctt cggtgatctt gggaatcaaa
   100621 tctttgccaa agtcgtggct ggagttctca tcacgatcgt cttcttccag cagttcatac
   100681 agatagtcgg cgtcaaagac gtagataccc atactcgcca gagatttgct cggatcgttc
   100741 ggcattgacg gtgggttagc aggtttttca acgaattcga taattttatc gttctcatca
   100801 accgccataa cgccaaatgc ggaggcttct tcaatcggta ctggcataca agcaacggtg
   100861 caacgtgcgc ctttttcgac gtgatcgata agcatacgcg agtagtcttg cttgtagata
   100921 tggtcgcccg ccaggatcac cacgtattcc gctttataac ggcggataat gtcgaggttt
   100981 tgggtgaccg catctgcggt gccgcgatac cagttttccc ctttcattct ctgctgtgct
   101041 ggcagcagat cgacaaactc gttcatttct tcattgaaga atgaccagcc gcgctgaatg
   101101 tgctgcacca gagtgtggga ctggtactgg gtgatcacgc ccatacgacg gatcccggag
   101161 ttgatgcagt tagacagcgc aaagtcgata atgcggaact taccgccgaa gtgtacggcc
   101221 ggttttgctc gcttattggt taaatccttc aggcgggtac cacgtcctcc cgccagtatc
   101281 agggcaacag atttcaatgg cagctggcgc gccaacatta agtgatcgtt cttctctaaa
   101341 ctaaccatga ctaactcctt ttttatcatc tctggaacac acacaatccg tgtgcaggtc
   101401 cctgccagac agccgtaatc actgggttat cctctccagc gaatggggga atggcgtgcc
   101461 actccccagc aggtaaaaca atctctgtta cctcaagcgt ggcgttaatt gcgatcaaaa
   101521 agcgatccga gagcagaatt tgcagctgtt tcggcccgtt ttgccactca tccgtgctta
   101581 aaggttgagc atatcgattt agccaacgga cattgccgtc gccttcttcc caccagcgat
   101641 tctccaccaa agcgggaatg cgcttgcgca gatggattaa cgcggcggta aatgcggtta
   101701 aaccactgct tgcctgcgac cagtccaacc aggttaattg gttatcctga cagtaggcat
   101761 tgttattgcc atgctggctg tgaccatgtt cgtcaccggc cagtaacatc ggcgtaccct
   101821 gggagagcaa caacgttgtt aacagggcgt gaatgctgtc gcgccgccgt tcaaccaggt
   101881 caagagaacc gcctaaccct tctttaccat gattgttact gtaattgttg ttggtcccgt
   101941 cgcgattttc ttctccgttt gcttcattgt gtttatggtt gaagcaaacg cagtcgcgaa
   102001 gcgtaaaacc gtcatgcgcg gtgacgagat taatcgcggc actcggcaga cgaccattac
   102061 gtttaaaaac atcgctggag gcagcaaaac gcccggcaaa cgcccccaga ggcaaatcat
   102121 aatgtagcca gaaacgacgg gcagcatcgc ggaaatgatc gttccactcg gcaaacagcg
   102181 gcgggaaatt tcccacctga taaccaccag gagcgatatc ccacggttca gcaattaact
   102241 tcacctgcga gagcaccggg cagttctgga tagcggtaaa caacggcgca tcctgacgga
   102301 actctggcgt acggcccatg actgccgcca gatcaaagcg gaaaccatcg acgtggcagg
   102361 tttctaccca ataacgcagg caggcgctgg cataatccac caccgccgga tgactcaaat
   102421 tgagcgtgtt gccgcaaccg gtccagttgt gataatcgcc gtcttctctt atccaataat
   102481 agctacggtt atcgatccca cgcagcgaga ataacgggcc gtcgaggtcc agttccgcac
   102541 tatggttgag cacgatatca agaatgactt cgatacccgc tttatgcagt gctttgattg
   102601 catcgcgaaa ctcatccagc gccgtttctg gcgagcaggc atacgccgga tgcagcgcaa
   102661 acatcgccac cgggttgtaa ccccagtagt tacttagccc catgcgttgc agacgtggtt
   102721 cactggcaaa ctgcgccact ggcagcagtt ccagcgcggt aatgcccaat tgtttcaaat
   102781 agttgatcat caccggatgc ccgagggctt tataagtgcc acggatctcg accgggatct
   102841 ccgggtgcaa gtacgttaat cctttgacat gggcttcata aatgatggtg ctgccccacg
   102901 gcgtgcgcgg cggggcatca tcttcccagt catagtgatc aaccaccact acgcatttcg
   102961 gcgcaatggc ggcgttgtcg cgatagtcag gttcattatg accggcgtgc agcagcgggt
   103021 tatctttaaa ctccccgtca atttgccgcg cgcaaggatc aatcaacaac ttcgccgggt
   103081 taaagcgatg cccctcggcg ggttgccagg ggccatgaac gcgataacca taacgcaaac
   103141 ccgggcgcgc atccggcaga taaccgtgcc aaatgtcgcc actgtgccct ggcaagtcat
   103201 agcgatgttc ctggccattg gcgtcaaaga cacacagttc tacccgctcg gcatgagcgg
   103261 agaaaagtgt gaagttgacg ccctgaccgt cgtaatgcgc gccgagggga gcgggtttgc
   103321 caatggcgag ttgtgtcatt ctgcctcccg aaccagccag atagtggcca gcggtggtag
   103381 cgtcaggctt agtgaatgct gacgaccgtg gctggcaatc tcatcgctgt gtaccgtgcc
   103441 gccattgcct gcattactgc cgtgatagtg catggaatcg gtattgagga tttcacgcca
   103501 tttgcccggc tggtttatgc cgaagcgata atcatgacgc ggtaccggcg taaagttact
   103561 ggcaacgatg atttcgttac cctctttatc gcgacgcaca aagatcagca ccgagcgttc
   103621 tttgtcatcc accaccagcc attcaaagcc gtacgggtca aaatccagtt catgcattgc
   103681 tttatggtgg cggtaggtga ggttcagatc gcgcaccaga cgctggacac cgtggtgcca
   103741 gttatcgccg ccttccaaca gatgccagtc gaggctggcg tcatggttcc actcgcggcc
   103801 ctgggcaaat tcgttaccca tgaacagtag tttcttgccc gggaatgccc acatccagcc
   103861 atagtaggcg cgcaggttcg cgaatttctg ccatgcgtcg cccggcatgc ggtcgagaat
   103921 cgatttttta ccgtggacca cttcatcatg cgacaacggc aggacgaagt tttcagtgta
   103981 gttgtagaga atcccgaagg tcagtttatc gtgatgatac tgacgataaa ccgggtcgag
   104041 cttcatgtag tccagggtgt catgcatcca gccgaggttc cacttgtacc agaagcccag
   104101 accgcccata tcctgcggac gagaaacgcc agggaaatcg gtagactcct cagccattgt
   104161 caccgcaccg gaaacctgct caccaagaat acggttggta ttacgcaaga attcaatcgc
   104221 ttcaagattc tcgcgcccgc caaattcgtt cgggatccac tccccctctt tacggctgta
   104281 gtcgcgataa atcattgacg ccaccgcatc gacgcgcagc gcatcaatac caaaacgttc
   104341 aatccagtaa agcgcgttac cgacgaggaa gttactgact tcacggcgac catagttgta
   104401 gatcagcgtg ttccagtcct gatgatagcc ttcacgcgga tcgctgtgtt catacaagtt
   104461 cgtgccatca aattcggcaa gcgcaaagtc atcagtcggg aagtggcctg gcacccagtc
   104521 gagaatcacg ttcagaccag ctgcgtgtgc ggcatcaatg aaataacgga agtcgtcgcg
   104581 agtaccaaaa cggcgggttg gtgcatacag gccggttggc tgataacccc aactgccatc
   104641 gaagggatgc tcgttaatgg gcagtagttc gaggtgggta aagcccatcc atttagcata
   104701 aggcaccagt tgatcggcca gctcgcggta gctcaaccag aaattgttgt cggtgtggcg
   104761 acgccaggaa cccaggtgaa cttcataaat agagattggc gcatcaaact gattcgcttt
   104821 tttgcgctct tcagtctgta caaccttttc cggcagcccg caaataagag acgcggtttc
   104881 cgggcgcatt tgcgcttcga aggcataagg gtcggacttc agacgcaagt tgccattggc
   104941 atcaatcatc tcgtatttat agagctgacc gttatgcgcc ccagggataa acagttccca
   105001 gatgccgctc tctttacgca ggcgcatcgg gtgacggcga ccgtcccagt agttaaattg
   105061 cccaaccacc gagacccgac gggcgtttgg agcccagaca gagaaacgcg tacctgtgac
   105121 gccatccata gtatctgcat gcgcgcctaa ggtttcatac gggcgcaggt gagtaccttc
   105181 agataatagc caggcatcca tttcctggat tagcggacca aaacggtaag gatcatcaat
   105241 caggttttgc tgaccatgcc agacaacagc caactgatag cggaaaaaat tcttacgtcg
   105301 cggaatgacg ccgctaaaga atccccgtga gtcgagacac tccagttttg cgagtttgcg
   105361 cccggttttc ggttcaatca cccacacatc ggtagcgtcg ggtaaaaggg cacggacttc
   105421 cagtcccgcg gtggttttat gcattcccag tacggaaaaa ggatccgcaa aatggcctgc
   105481 aattagcgcg ttaatcacgt ctctatcgat acgatcggac atgcttgtct tcctgtttta
   105541 ttgtgtcacc ccatccaatt ggatttttga cttctggttg tgacattttt ttgacctgaa
   105601 cggcgcagca ctctgtgcat cctctctgcg tcgtcctcac ttcaggtaag gctgtgaata
   105661 ctcatgtatt cagccaccct taaagaatag ccaatgctct atttaactcc cggtaaatca
   105721 tgaaacatct gcgcttactc ctgtattacg cactaacagg ggcggcatcg cgccccagat
   105781 ttaatgaata aagattacgc cagttgacga agcatccgac gcagcggctc cgcggccccc
   105841 cacagcagct ggtcgcccac ggtaaaggct gacaggaact ctggtcccat attcagctta
   105901 cgcaggcggc ctaccggcgt ggtcagcgtg ccggtaacgg cagctggggt tagctcacgc
   105961 atagtgattt cccgatcgtt cggaacgact ttcgcccacg gattgtgcgc agccagcagt
   106021 tcttccacgg tcggaataga cacatctttt ttcaatttaa tagtgaatgc ctggctgtgg
   106081 cagcgcaatg ccccgacacg cacacataaa ccatctaccg gaattacgga agatgtgttg
   106141 aggatcttgt tggtttccgc ctgccctttc cactcttcgc ggctctgacc gttatcgagc
   106201 tgtttgtcga tccacggaat caggctaccc gccagcggca cgccaaagtt atccaccggc
   106261 agctcaccgc tacgggttaa ggttgtgact ttgcgttcga tatcgagaat agcagaggac
   106321 ggggtcgcga gttcatctgc cacatggcca tacagatggc ccatctgggt taataactca
   106381 cgcatatgtc gcgcaccacc gccggaagcg gcctggtagg ttgcaacgga cacccaatca
   106441 acaagatcat tggcgaataa accacccaac gacatcaaca tcaggcttac ggtacagtta
   106501 ccgccaacaa aagtcctgat gccattattt aatccgtcgg taatgacgtc ctgattgacg
   106561 gggtcaagaa tgatgatggc gtcatctttc atgcgcagag acgatgctgc gtcaatccag
   106621 taaccttgcc atccgctttc acgaagcttt ggatagattt cgttggtata atcgccgccc
   106681 tgacaggtca caatgatatc gagggccttt agcgcctcca gatcaaaggc atcctgaagt
   106741 gtgccagtgg ttccgccaaa agacggcgca gcctggccaa gctgagaagt agaaaagaag
   106801 acagggcgaa tggcgtcgaa gtcgcgctct tcaaccatgc gttgcatgag aacggagccg
   106861 accataccgc gccagccgat aaaaccaaca tttttcataa gcgttttttt cctgcaaaga
   106921 tgtgtgctgt ataaatgtgc cggtctcctc ttggcacatc tttcaccata caaaaagcag
   106981 ccaaagtcgc aagtgaaatt aatcaatgat agcgaagcca tcagtaatgc gacttatcct
   107041 gctttgttag cacgcagaaa gtccgcggca attatcaggg aatttgagtt atgaatgaaa
   107101 tcatttctgc agcagtttta ttgatcctga ttatggatcc gctcggaaac ctacctattt
   107161 tcatgtccgt actgaaacat actgaaccga aaagacggcg ggcaatcatg gtgcgagagt
   107221 tgcttattgc tctcctggtg atgctggtgt tcctgtttgc gggtgagaaa attctggcat
   107281 ttctcagcct gcgagcagaa accgtctcca tttctggcgg catcattctg tttctaatcg
   107341 ccattaagat gattttcccc agcgcttcag gaaatagcag cgggcttccg gcaggtgaag
   107401 agccatttat cgtgccgttg gcaattccgt tagtcgccgg gccgactatt ctcgccacgc
   107461 tgatgttgct gtctcaccag tacccaaatc agatgggaca tctggtgatt gctctgctgc
   107521 tggcctgggg cggcaccttt gtcatcctgc tacagtcttc gctattttta cgtctgctgg
   107581 gcgagaaagg ggtgaacgca cttgaacgcc tgatgggatt gattctggtg atgatggcaa
   107641 cccagatgtt cctcgacggc attagaatgt ggatgaaggg gtaaggttca aacaggtgct
   107701 gcacacaacc agacgcggca cctgttttat tacctgaact gataatgacc ttcgcccaat
   107761 cggataaccc ttccctcttc ttctgcgcgg ttcagccaca cactaatttg ttcgatggtt
   107821 aaaccagtac aagacgacag cctttcaata cttatcgatt cctttgcaaa gatcgccagt
   107881 tccgccacaa agagttgata aaaatcgaca ggcgtatgcg cgggcattac tgcgtaattt
   107941 gcgtcatttt catgcagcga aaacagttct ggttgagcgt tacggagtgc tctgtcatac
   108001 atcagcccag gaacgtctga cagtctgatc ggcacattct cagcctgttc agcactccat
   108061 gacgccccat tttctactaa tcgtgaattg gctgattgca tatcctgatt tggtttaacc
   108121 tgcacaggca gccactgatg ttttaatgcc tctatcgccc cggttatcgt tccaccggtc
   108181 attcccgcac gtacaaccat tgcgctttca gcaaggcaat aaatatattt atttcgcgcc
   108241 atcgcattgc cgacggtgaa acgcacctct gggtaaaacg gcgaaatcaa caccaggttg
   108301 cctgctataa gcccttcacg ccatttcact aacgtactcg tttttaacaa gctatcagct
   108361 aatacgccaa cggcagttcc cccggcctcc agtgccgacg ccattgcaca ttcatcaata
   108421 cctcgcgcac caccagagat aacgcaaatc ccctgttggg ccagtttcgc ggccagttgt
   108481 tgggtatagc gcaaatcgtc agtcggagca tctcgcgagc caacaatcgc cataccttcc
   108541 gcttgcagta atgctttatt cccgcagcca aataaaacgg gaggtgcatc cgttcgcaat
   108601 cggtttttca agcgaacggg ataatcagca tctcctcggg ttatgatcca taaaccggcg
   108661 cgttgccact tatctaccgc caacgccaga ctatgaccgc gcgccagcaa gccaagaata
   108721 cgctcctgag aaatacgcgg atcgctccag cctgtaagtt tctcttgcgg ttgcggcacc
   108781 agaagctcgg cgggactgat acgttggtgc ttcagccata atgcaaactt cccccattca
   108841 ctattactaa gaggtttatg ctcactcgcc gccgcgcgag aaaaatcgct ggttagcagg
   108901 agagtcgctt gtgcattggc tgaaagattc atcaattttt taccgaggta gaagcaaggg
   108961 caagaggata aaccgtcggg caacctgcct ggcgtaacag tgctgtcaga actgtcagcg
   109021 tccatgcaga atccacgata tcgtcaacca gcaacgccgg acctggcatc aaaggagggg
   109081 taatcacaaa cgccccgtcg agattttgac actggtgaaa acggttttgc tgcattttct
   109141 gcggtggatt gtccacgact ttttcaatgg catcaataaa aggtaagcca agtttcgccg
   109201 ccagtcgccg ggcaaaatca ggaaccaggt cgaggtgcct taatgaagga acgcagcata
   109261 cccaggttgg ttcaggatgc ggattccagc gttggcgaac catttccgca catgcctcca
   109321 ccagctcatc actgaatcgc cccgtttttt tctcctgtgc tacctgcttt ccccatccgg
   109381 aatctcccca acgagaaagg actcgccccg tagatccttg taaacccgca ggcaagttcc
   109441 ctttaaatcc gtattgcgta aaagctccag atgctacctt tttattgaga tttaatggca
   109501 ggtcagcgtg tttaataaat aaatttgccg catggagtaa gccgctatca atatcgggcg
   109561 acaacaacgg atgctgaaga caactgctac atttaccaca acgttcggca cttggctcat
   109621 cgagtgcgcg gcgcagaaat tgcattttgc actccttggt cgtgatatag ctttcaacat
   109681 ctgccagctc attttttctc tgattcatca aatggttaat tcgttcatgg tcaggagaga
   109741 aactgacgat agttctgcgc cataatttct cggtatacac cacaggcgat ggattttcag
   109801 ctaccaataa tttcagtgct ttttctattt gcccataacg gagattcgtc cgttgttcaa
   109861 tgcctcgtag ggtaagaccg tcattctcgc taagtacgtt gagtatttca tgaatttgcg
   109921 cctccgcagg aaaggcgctt tcacggaaga atttatgaat agcgcggtct tcaccaccac
   109981 aaagcaatat gccaacagcg gaatctatag cacgcccggc acgccctacc tgttggtagt
   110041 aaccgacaat agaccccggc atctggtaat gaataacaaa ccccaaatcc ggtttgtcaa
   110101 agcccattcc cagcgccgtc gtcgcgacca gaactttaat tttatttgcc agcaacgcct
   110161 gctccagata ttccctggca gtattagaat cttccgcgcc ttcacaagtc acgccgctgt
   110221 agtaagcaaa tgcactgata ccatttgtcc ttaaccactc ggcgacaagg tcggcatcgc
   110281 gagtagtcag ggtataaaca attcccgatt tggaaaactg agggataacc gttgctaacc
   110341 atgccagacg ggatgactgt tcacctaaga ctaaggcatc aagcgccaaa ctttcgcgag
   110401 ccagcgttcc acgctgaatc acaatgtcac ccaattgctg acggatatcc tcaacgacac
   110461 ggttattcgc tgtcgcggtt gtacccagaa ctggggtatt cgcaggcagt tggcgcaaaa
   110521 tatctaatat acgtcggtaa tccgggcgaa aatcgtggcc ccaatcagag atgcagtgcg
   110581 cctcgtcgac cacaagcaag ccaatacgat cggctatagg atataaaacc gtttcgataa
   110641 agtcttggtt tgccaaacgt tccggggaaa ccagcaagca atcgacctca ccttgcagca
   110701 acttatcgct aatacgctgc cattcttccc tgtttgtaga attcaacgtt tcagccgtaa
   110761 tacctaaccg ttcagcggcg gcaacctggt tacgcatcag ggcaagcaaa ggagagatga
   110821 taattgtcgg gccagcaccg cgatcgcgga agattttact ggcgatgaag tacacggcac
   110881 ttttccccca gccagtgcgt tggacaacca gcagttttcg tcgttggttc accaccgcgt
   110941 ctatggcttc ccattgccct tccctgaaag tagcggtggt atttcctaac atccgctgta
   111001 aaagcaattc agctgcgtgc ttttccatct ttatctcctg cgatctttag gcagtgatta
   111061 gaacggatta ttagcaggta aatttgcgag agggatcaaa aagatgaaga gaggagataa
   111121 gagaaatgaa ttactgcgag caagctcgca gtaatttgtc gcagtaatta actcaacagc
   111181 tggaacgcaa tcatcccaac gatggcaccg acagtgccga ggatggtttc catcatggtc
   111241 caggttttca gcgtttcggc ttcggtcgcg ccggtaaatt taccgaacaa ccagaaaccg
   111301 gcgtcgttaa cgtggctgac aacaatcgaa ccaccagcga tacaaatcga cagcgccgcc
   111361 atttgcgcac cggagtagtt cagttgttca ataatcggca tcaccagtcc taccgccgtt
   111421 aaacaggcta cggtggcaga accctgaatg atgcgcactg cagctgccag cacgaagcag
   111481 gtgatagcaa tcggcaggcc catgccggtt aacgcttcgc ccagtgccgg acctacgcca
   111541 gagtcaacca gcacctgttt gaacacgccg cctgcaccaa tcaccagcag aatgatcccc
   111601 gccggttgca gcgcgtgacc gcaaatctcc atcactttgt cttttggcat gccctgacgc
   111661 attgccaggc cataaatcgc taccagacaa gcaaccagaa tcgcggtaaa cggatgacca
   111721 ataaactcga accattcgta agcggtagag ccttctggca caaaacgcgc ggcaatggtt
   111781 ttcagcccca ccagcaccag cggcaacagg atcagcgaca ggctgaatcc gaaagatggc
   111841 attttgcctt cgccgagatg cggttcgctg atgtcgtcag gaatatgcaa ctccacgtag
   111901 cggctgatga aattacccca cagcggcccg gcaataatca ttcccggaat tgccgcacac
   111961 aggccaatca ggatcatcca gccaaaatcg gcgttcatct gcgatgccag cagcattggc
   112021 gctggccctg gcaccaggaa cgccgccgct gccgccacgc ctgcgaataa tgggattacc
   112081 agcttcacca ggttcgtacc ggtgtggcgc gccattgaga aagcaacgct aatcagcaga
   112141 acaatcgcca cttcaaagaa cagcggtagc gcacagacca gccccgcaag gccgatggca
   112201 taatgcgcgc ggctgtgacc gaaggattta agcattttga cggcaatctg atcgactgcg
   112261 ccggtttcat gtaagatctt gccaaacata gctcccaggg cgacaaccac cgccaggaag
   112321 ccgagggtgc ctcccatccc tttttccatc gtcgctgcga ttttatcgag cggcataccg
   112381 gaaaaaaggc cagcccccat ggacaccacc atcaaagcca ggaaagcgtg catacgcgcc
   112441 ttcatgacta aaaacagcag cagtaaaaca gaccctactg ctgttaaaac aagcgttaat
   112501 gtagtcacta cttatttgcc ttttttaata acctcaatgg tgcttgccac aacaccttcc
   112561 agcggttgat cgatatccac caccagtaca tcagtttcgt ccgcacccgg ctcctgcagc
   112621 gtttcaaact gcgtcaccaa catttgggtt ttaaagaaat ggcctttgcg cgctttcagg
   112681 cggctttcaa tcacgtcaaa atcgcctttc aggtagatga aagagagatt cggattacct
   112741 tcacgcagca agtcgcgata gtgttttttc aatgcagaac agacgatcag tgacacttta
   112801 ttagtgcgct gcatagcaaa cgcggcgtcg ttcagcgcct gcaaccacgg tttgcgatcg
   112861 tcgtcattca gcggttcgcc agacgccatt ttttcgatat tgcgccgtgg atggaggaaa
   112921 tcgccatcaa gaaacgcggc atgaagttga tgcgccactt cactggcgac cgcagatttg
   112981 ccgctgcctg agacgcccat caagacgtaa atgtggtgat catggttagt cgtgctcaaa
   113041 gtggtgcccc cacaatacaa gaattaaaaa tgttacgggt aactgttatc ggtaacattg
   113101 tccggccgga caatatcaga agcaatatcc atccgtgcct taagtgtata agtgtgagct
   113161 acttcaaatt tgtgggctta aatagatccg cccggtgaca aggtgaaacc taaatctaac
   113221 attttcggtg tcacagattc gccacgaata cgcgccagca ggcgttcagc gccaatactg
   113281 cccatccgct cacgcggcgt cagcacgctc gccagtcgtg gctccatcac ctgaccaatg
   113341 tcatgaccgt ggaaaccggc aatcgccata tcgtcaggaa cttttaaccc cagacgctga
   113401 cattcaaacg ccgcgccgac cgccagatca tcattagtac agaacacgcc atccagctgc
   113461 ggatattccc gccgcgcctg gcgaatcagt tcaataccgg aagagtaaga agaagattgc
   113521 tcaaccatca cgctatacgg caccaggcct gcatccagca tcgcctgttc gtatcccttc
   113581 tgtttgatga tagtacgttc gtcgagacgt gcgccgagat aggcaatgtg gcgatgcccg
   113641 cgcgcaataa tggcggtagt catctggcgt gccgcttcaa agttatcaaa accgacggcg
   113701 atatcgaggc acggcgactg gctgtccatc aactccacca ccgggatccc cgccacttca
   113761 atcatcttta aggtgcgcgg cgtgtgggta cgttcggtga ggatcaggcc gtcgatattc
   113821 caggacagca tggattcgag acgttcttgc tccatttccg gtttataacc gtagtgcgcc
   113881 agcatcgtct gataaccgtg cgcgtcggtg acgctttcga ttccgcgtaa tacttccgcg
   113941 aaaacctggt tggtgagaga aggtaacagg acgccaatcg cccggctggt agcgttagag
   114001 aggatatcgg gcgcacgatt gggaatatag cccagttcat caagagcggc ggcaatcttg
   114061 ccgcgtagag cgacggaaac ctgctccggg ttacgcaaaa agcggctgac cgtcattttg
   114121 gtcacgccta cacggtcagc cacatcctga agtacgggtc ttttcttttt catcgtcctg
   114181 aaggtacaaa agagatagat tctcttagtt taacacggac gcatcagaac cttcccgggg
   114241 aaaacagtgc ttgtttacaa ttattagata tacactaaat caattgcatc gcattgtgct
   114301 aacgacgcgg caaaaccccg gaagcgtgca tcagcacgcg accggagcga gcgaggaagc
   114361 ctgcaaaaag gcaggcttca aagatgccgt tgagttttaa accggcggca gatcgaacag
   114421 taacacttcg ctgtcgctat ccgcatggat ggagattgcc tgctcatccc agattgccag
   114481 accatcgctg gtcgaggctt tcacgccgtt aatggtgaca ttgcctttca ccacctggat
   114541 ccagacgcgg cgttcagcgg caatctgatg caccgactgc tcatctttca gcaacgccca
   114601 acgatacagt tccatatcct gatgcacttt cagcgaacca tctcgcgcat ccggcgagag
   114661 caccagctgt ttgccctgca cggcatcgaa gcgacgctgt tcataacgcg gcgtaatgcc
   114721 attttcttca ggcatgatcc agatctgata cagatgcaga cgctcggtgc tgcttgggtt
   114781 gtactctgag tgacgaatac ccgtacccgc actcataatc tggaactcac ccgccggaac
   114841 ctgctcttta ttgcccatgc tgtcctgatg ctcaacagta ccttccagca cgtaggtcaa
   114901 aatttccata tctttatgcg ggtgagtgcc gaagccctgc cctgcttcaa tcacgtcgtc
   114961 gttaatcacg cgcagcgcgg aaaagcccat aaagttcgga tcgtaatagt tggcaaaaga
   115021 gaaagtatgc caggagtcca gccagccatg atttgcatga ccacgttcat ttgctttgcg
   115081 taagtagatc atttgtattc gccccatgaa tgatttcgat gggcttagtg tggacccgat
   115141 ctgcctggga tgatagaggg tgaaaattga cccctctgtt caaaaaaatt gaactattcg
   115201 aggggccatc aaacttactt agcgagagtt actgtggagg gagaggcttg ctcaaatccg
   115261 cgttcaagga tttccagatt cgtaagaact tcagattcct tgacgtaatt tggcgcaccg
   115321 tgggtgatgg tttgatacaa cgcatcataa acgcgcccgt aatcgcccat ctccggcttc
   115381 atctcttctc tgaccgtcac gccctcgtca ttgacatact ccagcacacc gaccgaatca
   115441 tccgctgcga atcccggttc gcccggcata atattagcct tcaggctggt ttcctgctgg
   115501 tcgataccgt atttaataaa cgaacctttc ttaccgtgaa cgataaattt cggataatcg
   115561 attttcacca gatggctggt tttgacgatg gctttcaggt cgccataaaa cagttgcgct
   115621 tcaaaggtgt cgtcaggatt ggctttatta cgcaggctgc ggatgtcata agcgacgtga
   115681 tccgggcgac cgaacagaga aataatctgg tccatcgtat gcacaccaag gccataaaac
   115741 gcgccatcct gcggcagccc aggtttggtc tctgccaccg ggcggtaata gtcaaaatgg
   115801 ctttccactt caacaatctc tcccaacttg ccactttcaa tcgctttttt cgctgtcagg
   115861 aagcaggagt caaagcgacg attctgatac ggcgtgacgg tcagcccttt gcttttcgcc
   115921 aacgcaaaca gctccttcgc ctgggcaagc gtcggggtga acggtttttc gaccagcaca
   115981 tttttcccgg cttccagcgc gcgtttcgcg tactcgaaat ggctgtccgc gtgggtgcag
   116041 acaacaacca gcttaacatc gggatcgttt agtacttcgt cgagatcgct ggtgaaatgg
   116101 atatgggaat aaatgggagc ctgttcttcc ggcttcgcat ggcgacgaaa aatatgcgcg
   116161 acatgccagc tatccttgcg gttaagtaca tacggcagat ggtaacgggt ggtgcttttg
   116221 ccgaagccaa taaaggcgca gttgatgacc atgatttcgt cctttttaag gtggttattt
   116281 acaccttagc gcaaagcgga cgtggttcct actggagtgc gcataacgaa cacaagcact
   116341 cccgtggata aattgagaac gaaagatcaa aaaaaagcca gcacccggct ggctaagtaa
   116401 tactggaagc aatgtgagca atgtcgtgct ttcaggttct ccgcgagggt cttcctgatc
   116461 gcgagacaat aataatcatt ctcattcgca cttgtccaac actttttgca aaaaaatgca
   116521 tttgactcgc atttgaaagt caatgatgtt gaaagggaca tttaccccaa agaggacaaa
   116581 ggaatgagtg agatagtaat acgccacgca gaaacacggg attacgaggc catcaggcag
   116641 attcacgccc agccggaggt gtattgcaac acactacagg tgcctcatcc ttccgatcat
   116701 atgtggcagg agcgactcgc cgatcgtccc ggcatcaagc aactcgtcgc ctgtattgat
   116761 ggagacgtcg tgggccatct caccattgac gtgcaacagc gcccacgccg cagtcatgtt
   116821 gccgattttg gtatctgtgt cgactctcgt tggaagaacc gcggcgtcgc cagcgccctg
   116881 atgcgagaga tgattgaaat gtgcgacaac tggttgcggg tagatcgcat tgaactaacc
   116941 gtgtttgtcg ataacgcccc ggcaattaag gtctataaaa aatacggctt tgaaattgaa
   117001 gggactggta agaagtacgc attgcgtaat ggtgaatatg tcgatgcata ttatatggcg
   117061 cgggtgaagt aagatagtgc cctttttctg agatggaaaa agggtgtcat tcaaaatcga
   117121 cataccttcc tttaaggtat ttatttgccc aatacatata ttgagattta actcataatt
   117181 acttcctaaa gtgtaatatt ttatttttta atatatacgc ctacaatttc ctggagtaaa
   117241 taaataacaa ttaacaagca taatattgcc attgataaaa tagcatgcca taaaaggact
   117301 tttcagggat gagtaatatt gtttacctga cagtaacggg agaacaacaa ggaagcatct
   117361 ccgcaggttg tgggacttct gagtctacag gtaatcgttg gcagagcggg catgaggatg
   117421 aaatatttac attctcactc ttaaataata ttaataatac ggggcttggt tcacagttcc
   117481 atggtataac attttgtaaa ttaattgata aaagcactcc attatttatt aattccatta
   117541 acaataatga acaattattt atgggatttg acttctatcg aa
//
LOCUS       DAZUDJ010000008       111418 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.008, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000008 DAZUDJ010000000
VERSION     DAZUDJ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 111418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 111418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..111418
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.008"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..2265
                     /gene="pdeI"
                     /locus_tag="ACHY1N_000841"
     CDS             <1..2265
                     /gene="pdeI"
                     /locus_tag="ACHY1N_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFS4043186.1"
                     /translation="IINYQLVSERAVKRADSRFELIQKNVGYFFKDIERSALTLKDSL
                     YLLKNTEEIQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQEQVNGPL
                     VDESGRVIFADFNPSKRPWSVASDDSNNSWNPAYNCFDRPGKKCISFTLRINGKDHDL
                     LAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKNQLAREKLIIYNSEGNYN
                     IIDSVDTEYIAKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYFM
                     TTRVFRRQFSEMTELVNTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIE
                     RSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIKLCGLEAVEAVFGVDERNKIV
                     RKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGYRNLRIH
                     KSAICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWIARNIRH
                     AMEIGELFLVYQPIVDINTRAILGAEALCRWVSAERGIISPLKFITIAEDIGFINELG
                     YQIIKTAMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTTIMKENGLKANSL
                     CVEITETVIERINEHFYLNIEQLRKQGVRISIDDFGTGLSNLKRFYEINPDSIKVDSQ
                     FTGDIFGTAGKIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPM
                     PFSAWDKSGKLVKE"
     gene            2273..3601
                     /gene="dgcI"
                     /locus_tag="ACHY1N_000842"
     CDS             2273..3601
                     /gene="dgcI"
                     /locus_tag="ACHY1N_000842"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFS4043187.1"
                     /translation="MSRINKFVLTVSLLIFIMISAVACGIYTQMVKERVYSLKQSVID
                     TAFAVANIAEYRRSVAIDLINTLNPTEEQLLVGLRTAYADSVSPSYLYDVGPYLISSD
                     ECIQVKEFEKNYCADIMQVVKYRHVKNTGFISFDGKTFVYYLYPVTHNRSLIFLLGLE
                     RFSLLSKSLAMDSENLMFSLFKNGKPVTGDEYNAKNAIFTVSEAMEHFAYLPTGLYVF
                     AYKKDVYLRVCTLIIFFAALVAVISGASCLYLVRRVINRGIVEKEAIINNHFERVLDG
                     GLFFSAADVKKLYSMYNSAFLDDLTKAMGRKSFDEDLKALPEKGGYLCLFDVDKFKNI
                     NDTFGHLLGDEVLMKVVKILKSQIPVDKGKVYRFGGDEFAVIYTGGTLEELLSILKEI
                     VHFQVGSINLSTSIGVAHSNECPTVERLKMLADERLYKSKKNGRAQISWQ"
     gene            complement(3648..4973)
                     /gene="rimO"
                     /locus_tag="ACHY1N_000843"
     CDS             complement(3648..4973)
                     /gene="rimO"
                     /locus_tag="ACHY1N_000843"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008172 - S-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HFS4043188.1"
                     /translation="MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTS
                     MVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV"
     gene            5186..5569
                     /gene="bssR"
                     /locus_tag="ACHY1N_000844"
     CDS             5186..5569
                     /gene="bssR"
                     /locus_tag="ACHY1N_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HFS4043189.1"
                     /translation="MFVDRQRIDLLNRLIDARVDLAAYVQLRKAKGYMSVSESNHLRD
                     NFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALATAAVCLMSGHHDCPTVITVNAD
                     KLENCLMSLTLSIQSLQKHAMLEKA"
     gene            5680..6795
                     /gene="yliI"
                     /locus_tag="ACHY1N_000845"
     CDS             5680..6795
                     /gene="yliI"
                     /locus_tag="ACHY1N_000845"
                     /EC_number="1.1.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose sugar dehydrogenase YliI"
                     /protein_id="HFS4043190.1"
                     /translation="MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLP
                     DNHGMLITLRGGELRHWQVGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWL
                     SYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
                     FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQG
                     MAMNPWSNALWLNEHGPRGGDEINIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAG
                     TEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRI
                     LTDRGQRIRDVRSGPDGYLYVLTDESSGELLKVSPRN"
     gene            complement(6792..7418)
                     /gene="gstB"
                     /locus_tag="ACHY1N_000846"
     CDS             complement(6792..7418)
                     /gene="gstB"
                     /locus_tag="ACHY1N_000846"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308945.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase GstB"
                     /protein_id="HFS4043191.1"
                     /translation="MITLWGRNNSTNVKKVLLTLEELELPYEQILAGREFGINHDADF
                     LAMNPNGLVPLLRDDESDLILWESNAIVRYLAAQYGQKRLWIDSPARRAEAEKWMDWA
                     NQTLSNAHRGILMGLVRTPPEERDQAAIDASCKECDALFALLDAELAKVKWFSGDEFG
                     VGDIAIAPFIYNLFNVGLTWTPRPNLQRWYQQLTERPAVRKVVMIPVS"
     gene            7665..8867
                     /gene="dacC"
                     /locus_tag="ACHY1N_000847"
     CDS             7665..8867
                     /gene="dacC"
                     /locus_tag="ACHY1N_000847"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HFS4043192.1"
                     /translation="MTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
                     KLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQP
                     NRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKASY
                     TLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRMWDFVMMKFH
                     QWFGSWFS"
     gene            complement(8914..9672)
                     /gene="deoR"
                     /locus_tag="ACHY1N_000848"
     CDS             complement(8914..9672)
                     /gene="deoR"
                     /locus_tag="ACHY1N_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HFS4043193.1"
                     /translation="METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNN
                     HSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKMAATLVEPDQTLFFDCGT
                     TTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQT
                     LNNFCPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPA
                     RMGDLKRFDIVVSDCCPEDEYVKYAQTHRIKLMY"
     gene            complement(9730..10326)
                     /gene="ybjG"
                     /locus_tag="ACHY1N_000849"
     CDS             complement(9730..10326)
                     /gene="ybjG"
                     /locus_tag="ACHY1N_000849"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFS4043194.1"
                     /translation="MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAAV
                     LWLWGLTAQRQLVIKIAIALAVSLFVSWTMGHLFPHDRPFVENIGYNFLHHAADDSFP
                     SDHGTVIFTFALAFLCWHRLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIG
                     CLSAQIIWQAMGHKLYQRLQSWYRFCFALPIRKGWVRD"
     gene            10611..11843
                     /gene="mdfA"
                     /locus_tag="ACHY1N_000850"
     CDS             10611..11843
                     /gene="mdfA"
                     /locus_tag="ACHY1N_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdfA"
                     /protein_id="HFS4043195.1"
                     /translation="MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIITCLAILLA
                     QNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWIHVLPWEGMFVLFAALAAISFFGLQQAMPETATRIGEKLSLKELGRDYKLVLKN
                     GRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLA
                     RLTSRRTVRSLIIMGGWPIIIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGL
                     VRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWL
                     SLMVIFLKDKQMGNSHEG"
     gene            complement(11884..12168)
                     /gene="ybjH"
                     /locus_tag="ACHY1N_000851"
     CDS             complement(11884..12168)
                     /gene="ybjH"
                     /locus_tag="ACHY1N_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YbjH"
                     /protein_id="HFS4043196.1"
                     /translation="MFMKNCLLLGALLMGFTGVAMAQSVTVDVPSGYKVVVVPDSVSV
                     PQAVSVATVPQTVYVAPAPAPAYRPHPYVRHLASVGEGMVIEHQIDDHHH"
     gene            complement(12254..13069)
                     /gene="ybjI"
                     /locus_tag="ACHY1N_000852"
     CDS             complement(12254..13069)
                     /gene="ybjI"
                     /locus_tag="ACHY1N_000852"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308951.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase"
                     /protein_id="HFS4043197.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVAS
                     GNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVFNGELSKDAFTTVVEHLLTRPEV
                     EIIACGKNSAYTLKKYDDAMKTVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQ
                     VQKALHEAIGDIMVPVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGN
                     DIEMLRQAGFSFAMENAGNAVVAAAKYRAGSNNREGVLDVIDKVLKHEAPFDQ"
     gene            complement(13069..14277)
                     /gene="ybjJ"
                     /locus_tag="ACHY1N_000853"
     CDS             complement(13069..14277)
                     /gene="ybjJ"
                     /locus_tag="ACHY1N_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4043198.1"
                     /translation="MTVNSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     SIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTMSCALVGMMILSLALWLTS
                     PLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMA
                     LTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQHGEKGVPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVAVVRASALMGALGIGLIIFVDSAWVAGVSVVLWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMLVVLALVILAAIVAKAVAKPD
                     TKTQTAMENS"
     gene            14361..14897
                     /gene="rcdA"
                     /locus_tag="ACHY1N_000854"
     CDS             14361..14897
                     /gene="rcdA"
                     /locus_tag="ACHY1N_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RcdA"
                     /protein_id="HFS4043199.1"
                     /translation="MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGS
                     MTYYFSGIDELLLEAFSSFTEIMSRQYQAFFSDVSDAPGACQAITDMIYSSQVATPDN
                     MELMYQLYALASRKPLLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTD
                     RKPLSREEILRMVERVAG"
     gene            complement(15072..16757)
                     /gene="ybjL"
                     /locus_tag="ACHY1N_000855"
     CDS             complement(15072..16757)
                     /gene="ybjL"
                     /locus_tag="ACHY1N_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HFS4043200.1"
                     /translation="MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVI
                     GLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLM
                     VFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG"
     gene            17027..17404
                     /gene="ybjM"
                     /locus_tag="ACHY1N_000856"
     CDS             17027..17404
                     /gene="ybjM"
                     /locus_tag="ACHY1N_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YbjM"
                     /protein_id="HFS4043201.1"
                     /translation="MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLF
                     FILPGAVASFFSQRREVLKPLFGAMLAAPCSMLIMRLFFSPTRSFWQELAWLLSAVFW
                     CALGALCFLFISSLFKPQHRKNQ"
     gene            complement(17434..17691)
                     /gene="grxA"
                     /locus_tag="ACHY1N_000857"
     CDS             complement(17434..17691)
                     /gene="grxA"
                     /locus_tag="ACHY1N_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 1"
                     /protein_id="HFS4043202.1"
                     /translation="MQTVIFGRPGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGIT
                     KEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVKENLDA"
     gene            17851..18138
                     /gene="ybjC"
                     /locus_tag="ACHY1N_000858"
     CDS             17851..18138
                     /gene="ybjC"
                     /locus_tag="ACHY1N_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjC family protein"
                     /protein_id="HFS4043203.1"
                     /translation="MRAIGKLPKSVLILEFIGMMLLAVALLSVSDTLSLPEPFSRPEV
                     QILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNRPPQYSRSEREKDNDANH"
     gene            18122..18844
                     /gene="nfsA"
                     /locus_tag="ACHY1N_000859"
     CDS             18122..18844
                     /gene="nfsA"
                     /locus_tag="ACHY1N_000859"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HFS4043204.1"
                     /translation="MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQ
                     CSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMAQNALTAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP
                     ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRQ
                     TIIKESRPFILDYLHKQGWATR"
     gene            18905..19807
                     /gene="rimK"
                     /locus_tag="ACHY1N_000860"
     CDS             18905..19807
                     /gene="rimK"
                     /locus_tag="ACHY1N_000860"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HFS4043205.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLR
                     SMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGG
                     AASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGI
                     DIAGKMIRWIERHATTEYCLKTGG"
     gene            19895..20371
                     /gene="ybjN"
                     /locus_tag="ACHY1N_000861"
     CDS             19895..20371
                     /gene="ybjN"
                     /locus_tag="ACHY1N_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HFS4043206.1"
                     /translation="MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVF
                     DAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH"
     gene            20723..21835
                     /gene="potF"
                     /locus_tag="ACHY1N_000862"
     CDS             20723..21835
                     /gene="potF"
                     /locus_tag="ACHY1N_000862"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0019808 - polyamine binding [Evidence
                     IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HFS4043207.1"
                     /translation="MTALNKKWLSGLVAGALMAVSVGTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSW
                     DLILKPENLEKLKSCGVSFLDAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDICVAIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAF
                     FDVFAMPADAKKKDEAYQFLNYLLRPDVVAHISDNVFYANANKAATPLVSAEVRENPG
                     IYPPADVRAKLFTLKVQDPKIDRVRTRAWTKVKSGK"
     gene            21930..23063
                     /gene="potG"
                     /locus_tag="ACHY1N_000863"
     CDS             21930..23063
                     /gene="potG"
                     /locus_tag="ACHY1N_000863"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015417 - ABC-type polyamine transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HFS4043208.1"
                     /translation="MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVDLSQVPPYLRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEIATRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGVLKERQEDGLVLDSPGLV
                     HPLKVDADASVVDNVPVHVALRPEKIMLCEEPPANGCNFAVGEVIHIAYLGDLSVYHV
                     RLKSGQMISAQLQNAHRHRKGLPTWGDEVRLCWEVDSCVVLTV"
     gene            23073..24026
                     /gene="potH"
                     /locus_tag="ACHY1N_000864"
     CDS             23073..24026
                     /gene="potH"
                     /locus_tag="ACHY1N_000864"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HFS4043209.1"
                     /translation="MNTLEPAAQSKPPGGFKLWLSQLQMKHGRKLVIALPYIWLILLF
                     LLPFLIVFKISLAEMARAIPPYTELMEWADGQLSITLNLGNFLQLTDDPLYFDAYLQS
                     LQVAAISTFCCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKN
                     NGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAA
                     LDLGARPLKTFFTVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQ
                     EFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG"
     gene            24023..24868
                     /gene="potI"
                     /locus_tag="ACHY1N_000865"
     CDS             24023..24868
                     /gene="potI"
                     /locus_tag="ACHY1N_000865"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HFS4043210.1"
                     /translation="MNNLPVVRSPWRIVILLLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELLRDDAMMSAVGLSLTIAACAATAAAILGTIAAVVLVRFGRFRGSNGF
                     AFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVIS
                     SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGAVGIVGFIAWYLMARAEKQRIRDIQ
                     RARHG"
     gene            24928..25416
                     /gene="ybjO"
                     /locus_tag="ACHY1N_000866"
     CDS             24928..25416
                     /gene="ybjO"
                     /locus_tag="ACHY1N_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HFS4043211.1"
                     /translation="MEDETLGFFKKTSSSHARLNVPALVQVAALAIIMIRGLDVLMIF
                     NTLGVRGIGEFIHRSVQTWSLTLVFLSSLVLVFIEIWCAFSLVKGRRWARWLYLLTQI
                     TAASYLWAASLGYGYPELFSIPGESKREIFHSLMLQKLPDMLILMLLFVPSTSRRFFQ
                     LQ"
     gene            25457..26584
                     /gene="rlmC"
                     /locus_tag="ACHY1N_000867"
     CDS             25457..26584
                     /gene="rlmC"
                     /locus_tag="ACHY1N_000867"
                     /EC_number="2.1.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0016070 - RNA metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /protein_id="HFS4043212.1"
                     /translation="MQCALYDAGRCRSCQWITQPIPEQLSAKTADLKNLLADFPVEEW
                     CAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALK
                     PFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSETKLAQLRKALPWLQE
                     QLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVA
                     SQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIASEAIACAKQSAA
                     ELGLTRLQFQALDSTQFATAQGEVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSC
                     NAQTMAKDIRELPGYRIERVQLFDMFPHTAHYEVLTLLVKQ"
     gene            complement(26759..27490)
                     /gene="artJ"
                     /locus_tag="ACHY1N_000868"
     CDS             complement(26759..27490)
                     /gene="artJ"
                     /locus_tag="ACHY1N_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein ArtJ"
                     /protein_id="HFS4043213.1"
                     /translation="MKKLVLAALLASFTFGASAAEKINFGVSATYPPFESIGANNEIV
                     GFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTT
                     PYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAF
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKINDQWFPQ"
     gene            complement(27782..28450)
                     /gene="artM"
                     /locus_tag="ACHY1N_000869"
     CDS             complement(27782..28450)
                     /gene="artM"
                     /locus_tag="ACHY1N_000869"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0071705 - nitrogen compound transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HFS4043214.1"
                     /translation="MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVL
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAF
                     ERRN"
     gene            complement(28450..29166)
                     /gene="artQ"
                     /locus_tag="ACHY1N_000870"
     CDS             complement(28450..29166)
                     /gene="artQ"
                     /locus_tag="ACHY1N_000870"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:0071705 - nitrogen compound transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HFS4043215.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVA
                     WAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGFVQIPVQMDIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLL
                     SQYILKRIDLRATRFERRPS"
     gene            complement(29173..29904)
                     /gene="artI"
                     /locus_tag="ACHY1N_000871"
     CDS             complement(29173..29904)
                     /gene="artI"
                     /locus_tag="ACHY1N_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein ArtI"
                     /protein_id="HFS4043216.1"
                     /translation="MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIV
                     GFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRRVEAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDGVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KLNTALEKVKKDGTYETIYNKWFQK"
     gene            complement(29922..30650)
                     /gene="artP"
                     /locus_tag="ACHY1N_000872"
     CDS             complement(29922..30650)
                     /gene="artP"
                     /locus_tag="ACHY1N_000872"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_process: GO:0003333 - amino acid transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HFS4043217.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQN
                     LIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGH
                     IVEQGDASCFTEPQTEAFKNYLSH"
     gene            complement(30868..31383)
                     /gene="ybjP"
                     /locus_tag="ACHY1N_000873"
     CDS             complement(30868..31383)
                     /gene="ybjP"
                     /locus_tag="ACHY1N_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFS4043218.1"
                     /translation="MRYSKLTMLIPCALLLSACTTVTPAYKDNGTRSGPCVEGGPDNV
                     AQQFYDYRILHRSNDITALRPYLSDKLATLLSDASRDNNHRELLTNDPFSSRTTLPES
                     ARVASASTIPNRDARNIPLRVDLKQGDQSWQDEVLMIQEGQCWVIDDVRYLGGSVHAT
                     AGTLRQSIENR"
     gene            31509..31832
                     /gene="ybjQ"
                     /locus_tag="ACHY1N_000874"
     CDS             31509..31832
                     /gene="ybjQ"
                     /locus_tag="ACHY1N_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFS4043219.1"
                     /translation="MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTA
                     VKTRR"
     gene            31829..32659
                     /gene="amiD"
                     /locus_tag="ACHY1N_000875"
     CDS             31829..32659
                     /gene="amiD"
                     /locus_tag="ACHY1N_000875"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiD"
                     /protein_id="HFS4043220.1"
                     /translation="MRRVFWLIAAALLLAGCAGEKGIVEKEGYQIDTRRQAQAAYPRI
                     KVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGI
                     SAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKP
                     ENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVDTASL
                     LELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
                     "
     gene            complement(32656..33669)
                     /gene="ybjS"
                     /locus_tag="ACHY1N_000876"
     CDS             complement(32656..33669)
                     /gene="ybjS"
                     /locus_tag="ACHY1N_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415389.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFS4043221.1"
                     /translation="MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMG
                     AEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
                     TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLA
                     SQEACDKLPSGRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMER
                     LGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAWLRDHGK
                     LPR"
     gene            complement(33768..35198)
                     /gene="ybjT"
                     /locus_tag="ACHY1N_000877"
     CDS             complement(33768..35198)
                     /gene="ybjT"
                     /locus_tag="ACHY1N_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2867 domain-containing protein"
                     /protein_id="HFS4043222.1"
                     /translation="MPQRILVLGASGYIGQHLVRTLSQQGHQILAAARHVDRLAKLQL
                     ANVSCHKVDLSWPDNLPALLQDIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVP
                     VKQLIFLSSLQAPPHEQSDHLRARQATADILREANVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPASEHRIFEAAGPEVLSYQQQ
                     FEHFMAVSGKRRWLIPIPLPTRWISVWFLNVITSVPPTTARALIQGLKHDLLADDTAL
                     RALIPQRLIAFDDAVRSTLKEEEKLVNSSDWGYDAQAFARWRPEYGYFAKQAGFTVKT
                     SASLAALWQVVNQIGGKERYFFGNILWQTRALMDRAIGHKLAKGRPEREYLQTGDAVD
                     SWKVIVVEPEKQLTLLFGMKAPGLGRLCFSLEDKGDYRTIDVRAFWHPHGMPGLFYWL
                     LMIPAHLFIFRGMAKQIARLAEQSTD"
     gene            complement(35209..36210)
                     /gene="ltaE"
                     /locus_tag="ACHY1N_000878"
     CDS             complement(35209..36210)
                     /gene="ltaE"
                     /locus_tag="ACHY1N_000878"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HFS4043223.1"
                     /translation="MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAA
                     ELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQP
                     IDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERN
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAI
                     RWRKMAGGGMRQSGILAAAGMYALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTN
                     MLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSREQLAEVAAHWRAFLAR"
     gene            complement(36247..37965)
                     /gene="poxB"
                     /locus_tag="ACHY1N_000879"
     CDS             complement(36247..37965)
                     /gene="poxB"
                     /locus_tag="ACHY1N_000879"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0052737 - pyruvate dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HFS4043224.1"
                     /translation="MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEW
                     MSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPEGATTHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKE
                     LVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQF
                     PYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKFLDK
                     ALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMK
                     LPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVD
                     EALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            complement(38098..39066)
                     /gene="hcr"
                     /locus_tag="ACHY1N_000880"
     CDS             complement(38098..39066)
                     /gene="hcr"
                     /locus_tag="ACHY1N_000880"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HFS4043225.1"
                     /translation="MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYAL
                     VSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSQWLTRDVKRGDYLWLSDAMG
                     EFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVRVIYNVRTPQDVIFADEW
                     RNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKALG
                     VTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAG
                     VCGCCKTKVVSGEYTVSSTMTLTDAEIAEGYVLACSCHPQGDLVLA"
     gene            complement(39078..40730)
                     /gene="hcp"
                     /locus_tag="ACHY1N_000881"
                     /gene_synonym="priS"
     CDS             complement(39078..40730)
                     /gene="hcp"
                     /locus_tag="ACHY1N_000881"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016661 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HFS4043226.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQG
                     LSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQC
                     LAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSIL
                     DAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRS
                     IVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA"
     gene            complement(40874..41773)
                     /gene="lysO"
                     /locus_tag="ACHY1N_000882"
     CDS             complement(40874..41773)
                     /gene="lysO"
                     /locus_tag="ACHY1N_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415395.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lysine exporter LysO"
                     /protein_id="HFS4043227.1"
                     /translation="MFSGLLIILVPLIVGYLIPLRQQAALKVINQLLSWMVYLILFFM
                     GISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRI
                     AMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQ
                     IVLNRRGMIVAVVVVVSSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMV
                     PAAIVHGFILSLLVPILIAFFSA"
     gene            complement(42268..42963)
                     /gene="aqpZ"
                     /locus_tag="ACHY1N_000883"
     CDS             complement(42268..42963)
                     /gene="aqpZ"
                     /locus_tag="ACHY1N_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015250 - water channel activity [Evidence
                     IEA];
                     GO_process: GO:0006833 - water transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="HFS4043228.1"
                     /translation="MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFG
                     LTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLI
                     ASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG
                     FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGII
                     GGLIYRTLLEKRD"
     gene            43389..45047
                     /gene="ybjD"
                     /locus_tag="ACHY1N_000884"
     CDS             43389..45047
                     /gene="ybjD"
                     /locus_tag="ACHY1N_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HFS4043229.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTP
                     CTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQA
                     KGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVE
                     HVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENVPMNLRKIISKAI
                     HRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD"
     gene            complement(45044..46000)
                     /gene="ybjX"
                     /locus_tag="ACHY1N_000885"
     CDS             complement(45044..46000)
                     /gene="ybjX"
                     /locus_tag="ACHY1N_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001322270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirK/YbjX family protein"
                     /protein_id="HFS4043230.1"
                     /translation="MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQ
                     KFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEAL
                     RYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILF
                     RNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVM
                     EAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHY
                     RLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG"
     gene            46151..47266
                     /gene="macA"
                     /locus_tag="ACHY1N_000886"
     CDS             46151..47266
                     /gene="macA"
                     /locus_tag="ACHY1N_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308991.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019898 - extrinsic component of membrane
                     [Evidence IEA];
                     GO_component: GO:1990195 - macrolide transmembrane
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1990961 - xenobiotic detoxification by
                     transmembrane export across the plasma membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HFS4043231.1"
                     /translation="MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPG
                     DLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIK
                     EVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDTAATEMAVKQAQI
                     GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA
                     DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYY
                     ARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETR
                     EREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ"
     gene            47263..49209
                     /gene="macB"
                     /locus_tag="ACHY1N_000887"
     CDS             47263..49209
                     /gene="macB"
                     /locus_tag="ACHY1N_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990195 - macrolide transmembrane
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HFS4043232.1"
                     /translation="MTPLLELKDIRRSYPAGDEQVEVLKGITLDIYAGEMVAIVGASG
                     SGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLT
                     AEQNVEVPAVYAGLERKQRLLRAQGLLQRLGLEDRTEYYPAQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRD
                     GEIVRNPPAIEKVNVAGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYD
                     DLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQ
                     EQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVL
                     RVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAETEQQLTRLLSLRHGKKDFFTWNMD
                     GVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVIERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTAT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(49282..49506)
                     /gene="cspD"
                     /locus_tag="ACHY1N_000888"
     CDS             complement(49282..49506)
                     /gene="cspD"
                     /locus_tag="ACHY1N_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HFS4043233.1"
                     /translation="MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVQFDVHQGPKGNHASVIVPVEVEAAVA"
     gene            49656..49730
                     /gene="yljB"
                     /locus_tag="ACHY1N_000889"
     CDS             49656..49730
                     /gene="yljB"
                     /locus_tag="ACHY1N_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YljB"
                     /protein_id="HFS4043234.1"
                     /translation="MNQKFEAVNAIDRNVTDVADANDR"
     gene            49829..50149
                     /gene="clpS"
                     /locus_tag="ACHY1N_000890"
     CDS             49829..50149
                     /gene="clpS"
                     /locus_tag="ACHY1N_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HFS4043235.1"
                     /translation="MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            50180..52456
                     /gene="clpA"
                     /locus_tag="ACHY1N_000891"
     CDS             50180..52456
                     /gene="clpA"
                     /locus_tag="ACHY1N_000891"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043335 - protein unfolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HFS4043236.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEV
                     SQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ELTYGFQSAQKHKAEAAH"
     gene            complement(52800..52887)
                     /locus_tag="ACHY1N_000892"
     tRNA            complement(52800..52887)
                     /locus_tag="ACHY1N_000892"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52851..52853),aa:Ser,seq:gga)
     gene            complement(53141..53359)
                     /gene="infA"
                     /locus_tag="ACHY1N_000893"
     CDS             complement(53141..53359)
                     /gene="infA"
                     /locus_tag="ACHY1N_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFS4043237.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(53644..54348)
                     /gene="aat"
                     /locus_tag="ACHY1N_000894"
     CDS             complement(53644..54348)
                     /gene="aat"
                     /locus_tag="ACHY1N_000894"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008914 - leucyl-tRNA--protein transferase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HFS4043238.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQR
                     GIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGC
                     ASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCSESMFS
                     RMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGR
                     LPNNFWVPRCLFSPQE"
     gene            complement(54390..56111)
                     /gene="cydC"
                     /locus_tag="ACHY1N_000895"
     CDS             complement(54390..56111)
                     /gene="cydC"
                     /locus_tag="ACHY1N_000895"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0034775 - glutathione transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HFS4043239.1"
                     /translation="MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLS
                     ASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDF
                     TLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGA
                     SDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVA
                     DRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAESL
                     RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDAT
                     TESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRY
                     YQFKQGL"
     gene            complement(56112..57878)
                     /gene="cydD"
                     /locus_tag="ACHY1N_000896"
     CDS             complement(56112..57878)
                     /gene="cydD"
                     /locus_tag="ACHY1N_000896"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0042883 - cysteine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HFS4043240.1"
                     /translation="MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWF
                     MARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFP
                     SNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGEL
                     DFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAH
                     PQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSL
                     LNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDA
                     SEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLL
                     LDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGR
                     YAELSVAGGPFATLLAHRQEEI"
     gene            complement(58001..58966)
                     /gene="trxB"
                     /locus_tag="ACHY1N_000897"
     CDS             complement(58001..58966)
                     /gene="trxB"
                     /locus_tag="ACHY1N_000897"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFS4043241.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNG
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK"
     gene            59511..60005
                     /gene="lrp"
                     /locus_tag="ACHY1N_000898"
     CDS             59511..60005
                     /gene="lrp"
                     /locus_tag="ACHY1N_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HFS4043242.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            60140..64207
                     /gene="ftsK"
                     /locus_tag="ACHY1N_000899"
     CDS             60140..64207
                     /gene="ftsK"
                     /locus_tag="ACHY1N_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFS4043243.1"
                     /translation="MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     SDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYE
                     DDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDE
                     EIIYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWA
                     APVEPVTQTPPVASVDVPPSQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQ
                     YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYAPAPEQPVAGNAWQAE
                     EQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQSVEQQPVVEPEPVVEETKPARPPLYY
                     FEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLAS
                     GVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYG
                     IKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQH
                     DVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGP
                     HEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVPPQQQYQQPQQPVAPQPQYQQPQQQV
                     APQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQQQDTLLHPLLMRNGDS
                     RPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGP
                     VITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTV
                     YLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAM
                     ILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMER
                     RYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLV
                     DEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAF
                     TVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKA
                     RGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIG
                     YNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD"
     gene            64362..64973
                     /gene="lolA"
                     /locus_tag="ACHY1N_000900"
     CDS             64362..64973
                     /gene="lolA"
                     /locus_tag="ACHY1N_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HFS4043244.1"
                     /translation="MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK"
     gene            64984..66327
                     /gene="rarA"
                     /locus_tag="ACHY1N_000901"
                     /gene_synonym="mgsA"
     CDS             64984..66327
                     /gene="rarA"
                     /locus_tag="ACHY1N_000901"
                     /gene_synonym="mgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein
                     RarA"
                     /protein_id="HFS4043245.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEVNDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR"
     gene            66418..67710
                     /gene="serS"
                     /locus_tag="ACHY1N_000902"
     CDS             66418..67710
                     /gene="serS"
                     /locus_tag="ACHY1N_000902"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFS4043246.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLF
                     HTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
     gene            67949..70393
                     /gene="dmsA"
                     /locus_tag="ACHY1N_000903"
     CDS             67949..70393
                     /gene="dmsA"
                     /locus_tag="ACHY1N_000903"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415414.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009389 - dimethyl sulfoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HFS4043247.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAH
                     AVDSAIPTKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGEGPDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDKKCEL
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDP
                     QGHHVAYKAFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTPGF
                     ESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGINNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDAKRVDKGGCINVLTTQRPSPL
                     AKGNPSHTNLVQVEKV"
     gene            70404..71021
                     /gene="dmsB"
                     /locus_tag="ACHY1N_000904"
     CDS             70404..71021
                     /gene="dmsB"
                     /locus_tag="ACHY1N_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase iron-sulfur subunit
                     DmsB"
                     /protein_id="HFS4043248.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            71023..71886
                     /gene="dmsC"
                     /locus_tag="ACHY1N_000905"
     CDS             71023..71886
                     /gene="dmsC"
                     /locus_tag="ACHY1N_000905"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     DmsC"
                     /protein_id="HFS4043249.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRV
                     IACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGW
                     LLAMLKKLSPALRTLWLVVTMVLGVVFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMF
                     MGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVMSVMQGTELATIHSSVQQAAA
                     LVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYG
                     LHMTVGMAVAS"
     gene            complement(71922..72548)
                     /gene="ycaC"
                     /locus_tag="ACHY1N_000906"
     CDS             complement(71922..72548)
                     /gene="ycaC"
                     /locus_tag="ACHY1N_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate family cysteine hydrolase YcaC"
                     /protein_id="HFS4043250.1"
                     /translation="MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALG
                     DLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDAPYIARPGNINAWDNEDFVKAVKA
                     TGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRMSQAGA
                     QLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK"
     gene            72863..74011
                     /gene="ycaD"
                     /locus_tag="ACHY1N_000907"
     CDS             72863..74011
                     /gene="ycaD"
                     /locus_tag="ACHY1N_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4043251.1"
                     /translation="MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVG
                     VVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRF
                     VAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSV
                     LPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITSMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV"
     gene            74221..75651
                     /gene="ycaM"
                     /locus_tag="ACHY1N_000908"
     CDS             74221..75651
                     /gene="ycaM"
                     /locus_tag="ACHY1N_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415419.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4043252.1"
                     /translation="MAGNVQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSW
                     VFIFALYFTPYALIVGQLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLA
                     QKPQAILIALGWAMKGDGSLIKEYSVVALQGLTLVLFIFFMWVASRGMKSLKIVGSVA
                     GIAMFVMSLLYVAMAVTAPAITEVHIATTNITWETFIPHIDFTYITTISMLVFAVGGA
                     EKISPYVNQTRNPGKEFPKGMLCLAVMVAVCAILGSLAMGMMFDSRNIPDDLMTNGQY
                     YAFQKLGEYYNMGNTLMVIYAIANTLGQVAALVFSIDAPLKVLLGDADSKYIPASLCR
                     TNASGTPVNGYFLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAF
                     IAVVRLAQKYKPEYVFIRNKPLAMTVGIWCFAFTAFACLTGIFPKMEAFTAEWTFQLA
                     LNVATPFVLVGLGLIFPLLARKANSK"
     gene            complement(75652..76560)
                     /gene="ycaN"
                     /locus_tag="ACHY1N_000909"
     CDS             complement(75652..76560)
                     /gene="ycaN"
                     /locus_tag="ACHY1N_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4043253.1"
                     /translation="MRMNMSDFATFFAVARNQSFRAAGDELGLSSSAISHSIKTLEQR
                     LKIRLFNRTTRSVSLTEAGSNLYERLRPAFDEIQIMLDEMNDFRLTPTGTLKINAARV
                     AARIFLMPLLVGFTREYPDIKVELTTDDSLVDIVQQGFDAGVRLSGIVEKDMISVAIG
                     PPVKLCVAATPEYFARYGKPRHPHDLLNHQCVVFRYPSGKPFHWQFAKELEIAVAGNI
                     ILDDVDAELEAVLMGAGIGYLLYEQIKEYLDTGRLECVLEDWSTERSGFQIYYPNRQY
                     MSCGLRAFLDYVKTGQICQSQRHRPQ"
     gene            76660..77250
                     /gene="ycaK"
                     /locus_tag="ACHY1N_000910"
     CDS             76660..77250
                     /gene="ycaK"
                     /locus_tag="ACHY1N_000910"
                     /EC_number="1.6.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H oxidoreductase"
                     /protein_id="HFS4043254.1"
                     /translation="MQSERIYLVWAHPRHDSLTAHIADAIHQRAMERKIQVTELDLYR
                     RNFNPVMTSEDEPDWKNMDKRYSPEVHQLYSELLEHDTLVVVFPLWWYSFPAMLKGYI
                     DRVWNNGLAYGDGHKLPFNKVRWVALVGGDKESFVQMGWEKNISDYLKNMCSYLGIED
                     ADVTFLCNTVVFDGQELHASYYQSLLSQVRDMVDAL"
     gene            complement(77332..78072)
                     /gene="pflA"
                     /locus_tag="ACHY1N_000911"
     CDS             complement(77332..78072)
                     /gene="pflA"
                     /locus_tag="ACHY1N_000911"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HFS4043255.1"
                     /translation="MSVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWD
                     THGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHT
                     CLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANK
                     NVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYK
                     LDGVKPPKKETMERVKGILEQYGHKVMF"
     gene            complement(78264..80546)
                     /gene="pflB"
                     /locus_tag="ACHY1N_000912"
     CDS             complement(78264..80546)
                     /gene="pflB"
                     /locus_tag="ACHY1N_000912"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFS4043256.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT
                     EAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTI
                     RLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQSM"
     gene            complement(80601..81458)
                     /gene="focA"
                     /locus_tag="ACHY1N_000913"
     CDS             complement(80601..81458)
                     /gene="focA"
                     /locus_tag="ACHY1N_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HFS4043257.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGTMPFGMAKLVGGICFSLGLILCVVCGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFASPEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRENDHH"
     gene            complement(81864..83624)
                     /gene="ycaO"
                     /locus_tag="ACHY1N_000914"
     CDS             complement(81864..83624)
                     /gene="ycaO"
                     /locus_tag="ACHY1N_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415425.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     accessory factor YcaO"
                     /protein_id="HFS4043258.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTR
                     QSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFVDWNFSGTTEEEFATLMAIFKKEDKEVYIADYEHLGVYACRIIVPGMSD
                     IYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQ
                     TLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAH
                     QSLLKAYEKLQRAKAAFWAK"
     gene            83754..84446
                     /gene="ycaP"
                     /locus_tag="ACHY1N_000915"
     CDS             83754..84446
                     /gene="ycaP"
                     /locus_tag="ACHY1N_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFS4043259.1"
                     /translation="MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQIS
                     VYFFEDDKVKPGLLILPSDCTQRYKVVPESADYACIRCSEIIHMKAGEKQLCPRCANP
                     EWTKASRAKRVT"
     gene            84645..85733
                     /gene="serC"
                     /locus_tag="ACHY1N_000916"
     CDS             84645..85733
                     /gene="serC"
                     /locus_tag="ACHY1N_000916"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004648 -
                     O-phospho-L-serine:2-oxoglutarate aminotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HFS4043260.1"
                     /translation="MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGK
                     EFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYW
                     AASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAID
                     ETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKA
                     NIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELL
                     YGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPLEGVKALTDFMVEFERRHG"
     gene            85804..87087
                     /gene="aroA"
                     /locus_tag="ACHY1N_000917"
     CDS             85804..87087
                     /gene="aroA"
                     /locus_tag="ACHY1N_000917"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFS4043261.1"
                     /translation="MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNL
                     LDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPL
                     AAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGG
                     NVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQ
                     HYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRF
                     ADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA"
     gene            87256..88020
                     /gene="ycaL"
                     /locus_tag="ACHY1N_000918"
     CDS             87256..88020
                     /gene="ycaL"
                     /locus_tag="ACHY1N_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706828.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase YcaL"
                     /protein_id="HFS4043262.1"
                     /translation="MKNTKLLLAIATSAALLTGCQNTHGIDTNMAISSGLNAYKAATL
                     SDADAKAIANQGCAEMDSGNQVASKSSKYGKRLAKIAKALGNNINGTPVNYKVYMTSD
                     VNAWAMANGCVRVYSGLMDMMNDNEIEGVLGHELGHVALGHSLAEMKASYAIVAARDA
                     ISATSGVASQLSRSQLGDIAEGAINAKYSRDKESEADDFSFDLLKKRGISTQGLVGSF
                     EKLASLDGGRTQSMFDSHPPSTERAQHIRDRIASGK"
     gene            88193..88876
                     /gene="cmk"
                     /locus_tag="ACHY1N_000919"
     CDS             88193..88876
                     /gene="cmk"
                     /locus_tag="ACHY1N_000919"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFS4043263.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQ
                     YARQKLALA"
     gene            88987..90660
                     /gene="rpsA"
                     /locus_tag="ACHY1N_000920"
     CDS             88987..90660
                     /gene="rpsA"
                     /locus_tag="ACHY1N_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFS4043264.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            90820..91104
                     /gene="ihfB"
                     /locus_tag="ACHY1N_000921"
     CDS             90820..91104
                     /gene="ihfB"
                     /locus_tag="ACHY1N_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006417 - regulation of translation
                     [Evidence IEA];
                     GO_process: GO:0075713 - establishment of integrated
                     proviral latency [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HFS4043265.1"
                     /translation="MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            91311..93575
                     /gene="ycaI"
                     /locus_tag="ACHY1N_000922"
     CDS             91311..93575
                     /gene="ycaI"
                     /locus_tag="ACHY1N_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309023.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HFS4043266.1"
                     /translation="MKITTVGVCIICGIFPLLILPQLPGTLTLAFLTIFACVLAFIPV
                     KTVRYIALTLLFFVWGILAAKQILWAGETLTGATQDAIVEITTTDGMTTHYGQITHLQ
                     GRRIFPAPGLVLYGEYLPQAVCAGQLWSMKLKVRAIHGQLNDGGFDSQRYAIAQHQPL
                     TGRFLQASVIEPNCSLRAQYLASLQTTLQPYMWNAVILGLGMGVRLSVPKEIKNIMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRSGQIFLPGRWIHWQIPLIGRICCAAFYAWLTG
                     MQPPALRTVVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPVAILSQSLWLSAAAV
                     AALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANL
                     FAIPLVTFITVPLILAAMVVHLSGPLILEQGLWFLADRSLALLFWGLKSLPEGWINIA
                     ERWQWLSFSPWFLLVVWRLNAWRTLPAMCVAGGLLMCWPLWQKPRPDEWQVYMLDVGQ
                     GLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHLDHRGGL
                     DSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSVHWPLQASNDKGNNHSCVVK
                     VDDGMNSILLTGDIEVPAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKV
                     ALASASRYNAWRLPSNKVKHRYQQQGYTWLDTPHQGQVTVNFSAQGWRISSLREQILP
                     RWYHQWFGVPVDNG"
     gene            93612..95360
                     /gene="msbA"
                     /locus_tag="ACHY1N_000923"
     CDS             93612..95360
                     /gene="msbA"
                     /locus_tag="ACHY1N_000923"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0034040 - ATPase-coupled lipid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HFS4043267.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRR
                     RLFDHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRV
                     IERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQI
                     EEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLL
                     EHRGVYAQLHKMQFGQ"
     gene            95357..96343
                     /gene="lpxK"
                     /locus_tag="ACHY1N_000924"
     CDS             95357..96343
                     /gene="lpxK"
                     /locus_tag="ACHY1N_000924"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009029 - tetraacyldisaccharide 4'-kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HFS4043268.1"
                     /translation="MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYSGKAESYPLLLSADTT
                     TAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVE
                     IVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNL
                     RTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALV
                     SAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTSLASGN"
     gene            96380..97612
                     /gene="ycaQ"
                     /locus_tag="ACHY1N_000925"
                     /pseudo
     CDS             96380..97612
                     /gene="ycaQ"
                     /locus_tag="ACHY1N_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706834.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="crosslink repair DNA glycosylase YcaQ"
     gene            97664..97846
                     /gene="ycaR"
                     /locus_tag="ACHY1N_000926"
     CDS             97664..97846
                     /gene="ycaR"
                     /locus_tag="ACHY1N_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HFS4043269.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPV
                     LLETEARVLTADESKS"
     gene            97843..98589
                     /gene="kdsB"
                     /locus_tag="ACHY1N_000927"
     CDS             97843..98589
                     /gene="kdsB"
                     /locus_tag="ACHY1N_000927"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008690 - 3-deoxy-manno-octulosonate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HFS4043270.1"
                     /translation="MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAER
                     IIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEP
                     MIPATIIRQVADNLAQRQVGMATLAAPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAKDLETVGDNFLRHLGIYGYRAGFIRRYVTWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAQEVPGTGVDTPEDLERVRAEMR"
     gene            98743..99636
                     /gene="ycbJ"
                     /locus_tag="ACHY1N_000928"
     CDS             98743..99636
                     /gene="ycbJ"
                     /locus_tag="ACHY1N_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HFS4043271.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLM
                     ARSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEA
                     PARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYLQHVEVLWTTLN
                     QFNNTGLTMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMV
                     GPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFSRRNFDLASKSLLPWLA"
     gene            complement(99613..100392)
                     /gene="elyC"
                     /locus_tag="ACHY1N_000929"
     CDS             complement(99613..100392)
                     /gene="elyC"
                     /locus_tag="ACHY1N_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HFS4043272.1"
                     /translation="MLFTLKKVIGNMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFIS
                     IGWLALLLLSLQPVADRLLRPIESTYPTWNNSQKVDYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPREQIITLD
                     LPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRVGYETLGRIWQWLKGPSGEPRQE"
     gene            100528..101313
                     /gene="cmoM"
                     /locus_tag="ACHY1N_000930"
     CDS             100528..101313
                     /gene="cmoM"
                     /locus_tag="ACHY1N_000930"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HFS4043273.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ
                     KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDKMQFIHCAA
                     QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
                     VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK
                     HQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQSKDKV"
     gene            101310..102632
                     /gene="mukF"
                     /locus_tag="ACHY1N_000931"
     CDS             101310..102632
                     /gene="mukF"
                     /locus_tag="ACHY1N_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005509 - calcium ion binding [Evidence
                     IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HFS4043274.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALR
                     DEEVTGELPPDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            102613..103317
                     /gene="mukE"
                     /locus_tag="ACHY1N_000932"
     CDS             102613..103317
                     /gene="mukE"
                     /locus_tag="ACHY1N_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HFS4043275.1"
                     /translation="MSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDENEENQPDSGEEE"
     gene            103317..107777
                     /gene="mukB"
                     /locus_tag="ACHY1N_000933"
     CDS             103317..107777
                     /gene="mukB"
                     /locus_tag="ACHY1N_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HFS4043276.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVLPTQLVTETLNERQARVLPLNELKDKLEAM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMR
                     HANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAK
                     ELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARI
                     ASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTS
                     SQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHE
                     NDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQ
                     FGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSY
                     SDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDL
                     RSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRAPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS"
     gene            108038..109885
                     /gene="ldtD"
                     /locus_tag="ACHY1N_000934"
     CDS             108038..109885
                     /gene="ldtD"
                     /locus_tag="ACHY1N_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HFS4043277.1"
                     /translation="MLLNMMCGRRLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAV
                     SEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARD
                     MQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGY
                     LHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYA
                     AMHESLLALLSDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGD
                     DTPTDAVVSPSAVTVETAETKPMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGL
                     GADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNG
                     NQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESH
                     GYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYL
                     HDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNI
                     RQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR"
     gene            110066..110614
                     /gene="mepK"
                     /locus_tag="ACHY1N_000935"
     CDS             110066..110614
                     /gene="mepK"
                     /locus_tag="ACHY1N_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF882 domain-containing protein"
                     /protein_id="HFS4043278.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTR
                     KPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            110641..111288
                     /gene="gloC"
                     /locus_tag="ACHY1N_000936"
     CDS             110641..111288
                     /gene="gloC"
                     /locus_tag="ACHY1N_000936"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase GloC"
                     /protein_id="HFS4043279.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDD
                     SGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEEC
                     QPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGR
                     SDFPRGDHNQLISSIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW"
BASE COUNT        27427 a        27333 c        29472 g        27186 t
ORIGIN      
        1 atcattaact atcaactggt atcggaacgc gcggtaaaac gtgccgatag tcgctttgaa
       61 cttattcaga aaaacgttgg ctatttcttt aaagatattg aacgttcggc cctgacatta
      121 aaggactcac tgtatttatt aaaaaataca gaggagattc aacgcgccgt gattctgaaa
      181 atggaaatga tgccattttt agactcggtg ggactggtac ttgatgataa taaatattat
      241 ctcttttcgc ggagggcgaa tgataaaatc gttgtttatc atcaggaaca agtaaatgga
      301 ccgcttgtcg acgagtcagg gcgggttatt tttgccgatt ttaacccatc gaaacgaccg
      361 tggtcggtgg cttcagatga ctctaacaac agctggaatc cggcatacaa ttgctttgat
      421 cgtccgggta aaaaatgtat ctcttttacg ctacgtatca acggcaaaga tcacgatttg
      481 ttagcggtag ataaaattca tgtcgattta aactggcggt atctgaacga gtatcttgat
      541 caaatcagcg ctaatgatga agttctattt ttgaaacaag gtcatgagat cattgccaag
      601 aatcaactcg ctcgtgaaaa actgattatt tataatagcg aaggtaatta taatattatt
      661 gattctgtcg atacggagta tattgcaaag acatcagcag tgccaaataa tgcattgttc
      721 gaaatctatt tttattatcc tggcggtaat ttattgaacg catcagataa acttttttat
      781 ctaccgtttg ctttcattat tatcgtgttg ctggtggtat atttcatgac cactcgtgtg
      841 ttccgtcggc aattttctga aatgaccgag ctggttaata cgctggcgtt tttgcccgac
      901 tcaacggatc aaatcgaggc tctgaaaatt cgcgaaggcg atgcgaaaga gattatcagc
      961 atcaaaaatt cgatcgcgga aatgaaagat gccgaaattg aacggtcaaa taaattgctc
     1021 tcactgatct cttacgatca ggaaagcggt tttattaaaa atatggcgat tattgagtcc
     1081 aacaataatc agtatctggc tgtggggatc atcaaactgt gtggtctgga agccgtggaa
     1141 gcggtgtttg gtgttgatga acgcaataaa atcgtcagga aattgtgtca gcgaattgcc
     1201 gagaaatatg cgcaatgctg cgatatcgtg acattcaatg ccgatctcta tttacttctg
     1261 tgtcgggaaa atgtacagac atttacccgt aaaatagcga tggtaaacga ttttgacagc
     1321 agctttggct accgcaatct gcgcatccat aagtctgcca tttgtgaacc tttgcagggg
     1381 gaaaacgcct ggagttacgc agaaaaactg aaactggcga tttccagtat ccgtgaccat
     1441 atgttctccg agtttatttt ttgtgatgac gcgaaactca acgaaataga agagaatatc
     1501 tggattgcgc gtaatattcg ccatgcaatg gaaattggcg aactattcct cgtctatcaa
     1561 ccgatcgttg atattaacac ccgcgccatt ctgggcgcgg aggcgttgtg ccgttgggtg
     1621 tctgcggagc gggggatcat ttcaccgctg aagttcatta ccattgctga agatatcggg
     1681 tttatcaatg agctgggtta tcagattatt aaaacggcaa tgggtgaatt tagacatttt
     1741 agtcagcgtg cgtcgctgaa ggatgatttc ttactgcata ttaatgtttc gccctggcag
     1801 ttaaacgaac cgcactttca tgagcgtttt accaccatca tgaaagaaaa tggcctgaag
     1861 gcgaacagcc tctgtgttga gatcactgaa accgtgatcg agcgaattaa tgaacatttt
     1921 tatctcaata ttgaacaact gcgtaaacaa ggggtacgga tatcgattga tgactttggc
     1981 accggtttgt caaacctgaa acgtttttat gaaattaatc cagatagcat aaaagtggac
     2041 tcgcaattta ccggcgatat tttcggtact gcgggaaaaa ttgtgcgcat tattttcgat
     2101 ctggcgcgct ataaccggat cccggtgatt gcggaaggcg tagagagcga agacgttgcg
     2161 cgcgaattaa tcaaattagg atgtgttcag gcccaagggt atctgtacca gaaacccatg
     2221 ccattctccg cctgggataa aagtggaaaa ttagtaaaag agtagtttac gtatgtccag
     2281 aatcaataag ttcgtactta cagtcagtct gctgattttt atcatgattt cagcagttgc
     2341 ctgcgggatc tacactcaaa tggtaaagga acgggtgtat agcctgaaac agtccgttat
     2401 tgatactgct tttgcggtgg caaatattgc tgaatatcgg cgtagcgtgg caattgatct
     2461 tatcaatacg ctaaatccca cggaggaaca gctgttggtt ggcttacgca cagcttacgc
     2521 tgactcggtt tcaccctctt acttgtacga tgtcggtcct tatctgattt ccagtgacga
     2581 atgtattcag gtaaaggagt tcgagaaaaa ttattgtgca gatattatgc aggttgtgaa
     2641 gtatcgacat gtcaaaaata cagggtttat ctcttttgac ggtaaaacct tcgtctatta
     2701 cctctatccg gtaactcaca atcgtagtct gatatttttg cttggtctgg agcgtttttc
     2761 tttactgtca aaatcgctgg cgatggacag cgagaacctg atgttctctc tgtttaagaa
     2821 cggtaaaccg gtgaccggtg atgaatataa tgctaaaaac gccatcttca ccgtttcgga
     2881 agcgatggag cacttcgcct atttgccgac cggattgtat gtatttgcgt ataaaaaaga
     2941 tgtttatttg cgggtttgta cattgattat tttctttgcc gcattggtgg cagtgatatc
     3001 gggtgccagt tgcctctatc tggtacgcag agtgattaat cgtggtattg tggagaaaga
     3061 agccatcatt aataaccatt ttgaacgcgt actggatggc gggcttttct tttcggctgc
     3121 cgatgtcaaa aaactctaca gtatgtataa ctcggcgttc ctggacgacc tgaccaaagc
     3181 aatgggcaga aaatcctttg acgaagattt aaaagcgctg ccggaaaaag gcggttattt
     3241 gtgcctgttt gacgtcgata aattcaaaaa cattaacgac accttcggtc atttgctggg
     3301 cgatgaagtg ttgatgaaag tggtgaaaat ccttaaatca cagatcccgg tagataaagg
     3361 taaagtctac cgcttcggcg gtgacgaatt tgcggtgatt tatacgggtg gaacgctgga
     3421 agagttgcta tcgattctaa aagaaatcgt tcatttccag gtgggaagca ttaatttaag
     3481 taccagtatc ggtgtagcac attcaaatga atgtcctacc gtcgaacgct tgaaaatgct
     3541 ggcggatgag cggctgtata agagtaagaa aaacggcagg gcacagatta gctggcagta
     3601 atcattattc gcaggccgga caaatgattt tgcccggcct gaattaatta aacccggcta
     3661 ccccacaaat cgtactcatc ggcgtgctcg actttcacac gcaggatatc acccggctta
     3721 acgttggttt caccattgag ataaaccgcg ccgtcgattt ccggtgcatc tgccatgctg
     3781 cgaccaattg cgccttcttc gtccacttcg tcgataatca ccagaatttc acggcccact
     3841 ttctcttgca ggcgctcggc ggaaatctgc tgctgcagct gcatgaaacg gttccagcgt
     3901 tcttctttca cttcttccgg aacctggtca ggcagggcat tggcgtctgc accttcaacc
     3961 gggctgtatt taaagcagcc aacgcgatcc agacgcgctt ctttcaggaa gtcgagtagc
     4021 atctggaaat cttcttctgt ctcgccaggg aagccgacaa taaaggttga gcgtagggtc
     4081 agttccgggc agatttcgcg ccactgtttg atgcgcgcca gttggcgatc tacagaaccc
     4141 ggacgcttca tcagtttgag aatgcgcggg ctggcgtgct gcaacggaat gtccagatac
     4201 ggcaggattt tgccttctgc catcagtggg atgacgtcgt ccacatgcgg ataagggtaa
     4261 acgtagtgca gacgtgtcca gatccccagt ttcgataact gttcgcacag gctgaccatg
     4321 ctggttttta ccggctcgcc gttgtggaag ccagtacgat gtttaacatc aacgccatag
     4381 gcggaagtat cctgcgagat caccagaatc tctttaacgc ccgcatctac cagacgtttc
     4441 gcttcactta acacttcgcc aatcggacgg ctcaccaggt cgccgcgcat agacggaata
     4501 atgcagaagg tgcagcggtg attacagcct tctgaaattt tcagataggc ataatgacgc
     4561 ggtgtcagtt tcacaccttg ttctggcacc aggctcagga atgggttgtg tttcggtttt
     4621 ggcacgtagt gatgaacgtg ctccagaacc tgctcatagc tatgaggccc ggtgatttcc
     4681 agcactttcg ggtggacttc gcggatctga tcttcttttg cccccagaca accggtcaca
     4741 attaccttgc cgttttcatt caacgcttca ccaatggctt ccagtgattc ttgtaccgcg
     4801 ctgtcaataa agccgcaggt gttgacgatc accatgtccg catcgtcata gctcggtacc
     4861 acgtcataac cttcagtgcg tagttcggtg agaatacgct ctgaatcgac aaggtttttc
     4921 ggacagccaa gggaaacaaa gccgattttc ggctggggag ttactttgct catagcttaa
     4981 aaaatattca gttacaggaa aggtcagggc agggattcta cagagttctg gataaaattt
     5041 gtatcgcaat ctcattcgct ggcggaggcg aaggaaatgt aaattttgtt aatttggcgt
     5101 gaagaattga tcctggacag cattttgctc aaaaaatagc catactattt aattgcaaca
     5161 aggctggaaa gaggaggatc gaagtatgtt cgttgacaga cagcgaatcg atctgctgaa
     5221 ccggttgatc gacgcacgcg ttgacctcgc cgcatacgtg caactgagga aggcaaaagg
     5281 atacatgtcc gtcagcgaaa gcaatcatct acgagataac ttttttaaac tgaatcgcga
     5341 actgcacgat aaatcgctgc ggttgaatct tcatctggat caggaagagt ggagtgctct
     5401 tcatcatgct gaagaagcat tagcgacagc cgcagtatgt ttgatgagtg ggcaccatga
     5461 ttgcccgact gttattaccg tcaacgccga taagcttgaa aattgtctga tgagcttaac
     5521 gctgagtatc cagagcctgc agaagcacgc catgcttgag aaggcctgaa aactaagggg
     5581 gagaaagcgt ctcccccttc atgtttaagt ttttgtaaaa atgaatttgt tatctcctcc
     5641 actgactacg ctttaagcca gagtcaatcc ggaggcgtta tgcatcgaca atcctttttc
     5701 cttgtgcccc ttatttgtct ttcttccgct ctctgggcgg ctcctgcaac ggtaaatgtc
     5761 gaagtactgc aagacaaact cgaccatccc tgggcactgg cctttttacc cgataatcac
     5821 ggtatgttaa tcactctgcg cggcggcgag ttgcgtcact ggcaagtagg aaaaggatta
     5881 tctgcgccgc tttccggagt tccggacgtt tgggcgcacg ggcagggcgg cctgctggac
     5941 gtggttttag cgcctgattt tgctcagtct cgccgcatct ggttaagtta ttccgaagtt
     6001 ggcgatgatg gcaaagccgg aactgctgtg ggttatggcc gcttaagtga tgatctctca
     6061 aaagtgaccg acttccgcac cgtcttccgc cagatgccaa aactgtctac cggcaaccat
     6121 tttggcgggc ggctggtatt cgacggtaaa ggttatcttt ttattgctct gggcgaaaac
     6181 aatcagcgcc cgacggcgca ggatctggat aaattacagg gcaaactggt gcgtctgacc
     6241 gaccagggcg aaatcccgga tgataatcct tttataaagg aatccggtgc gcgcgccgag
     6301 atctggtctt atggcattcg taatccgcaa ggaatggcga tgaatccgtg gagtaatgca
     6361 ctgtggctga atgaacatgg cccgcgcggt ggtgatgaaa ttaatatccc gcaaaaaggc
     6421 aaaaactacg gctggccgct ggcaacctgg ggaatcaact attcaggctt taagataccg
     6481 gaagcgaaag gggagatcgt cgccgggacc gagcaacctg ttttttactg gaaagattcg
     6541 cccgctgtga gcggcatggc cttctataac agcgataaat tcccccagtg gcagcaaaaa
     6601 ttatttatag gcgcgctgaa agataaagat gtcattgtga tgagcgtcaa cggcgacaaa
     6661 gtgacagaag atggccgtat tttaacggac agagggcagc gaattcgtga tgttcgctct
     6721 ggacccgacg gttatttata cgttctcacc gacgagtcca gtggggaatt acttaaagtt
     6781 agcccacgca attagctaac gggaatcatc accactttgc gcactgcggg gcgttcagtg
     6841 agttgctgat accagcgttg cagatttgga cgcggtgtcc aggtcaggcc aacgttaaac
     6901 aaattgtaga tgaacggtgc gatagcgata tcgcccacac caaactcgtc gccagagaac
     6961 cattttactt ttgccagttc cgcatcgagc agggcaaaca gggcgtcgca ctctttgcaa
     7021 ctggcatcaa tggcggcctg atcgcgctct tcgggtggtg ttctgactaa tcccatcagg
     7081 atcccgcgat gagcattact gagtgtctgg tttgcccagt ccatccattt ttccgcttcc
     7141 gcacgacgtg ccggtgagtc gatccacagg cgtttttgcc cgtactgtgc cgccagatag
     7201 cggacaatgg cgtttgattc ccaaagaatg agatcacttt cgtcgtcacg caacaacggc
     7261 accagcccgt tagggttcat cgccagaaaa tcagcatcgt gatttatccc aaactcacgg
     7321 cccgcgagaa tttgctcata aggtagttcc agttcttcga gcgtcagcaa tacttttttt
     7381 acgttagttg aattattccg accccacagc gtaatcatac tcaccccttt tccgacaggc
     7441 agccacaggc tgaacaggac tccgatggtg aagtaaagtt aacttttaag caacagctgg
     7501 caaaaaaatg acaccagaag cagcgaagcg gcaggatatt gcataaactt taaaaacttt
     7561 accaacttac ggtttcttta agtttgtgtg tgcgttatta atcaccgaac ttatcatacg
     7621 gcgatataac gtattttttt tgaatggata ctcgggtggc atttatgacg caatactcct
     7681 ctctccttcg tggtcttgca gcgggttctg catttttatt cctttttgcc ccaacggcat
     7741 tcgcggcgga acaaaccgtt gaagcgccga gcgtggatgc gcgtgcatgg attttaatgg
     7801 attacgccag cggtaaagtg ctggcagaag gcaacgcgga tgagaaactg gatcccgcga
     7861 gcctgactaa aatcatgacc agctatgtgg ttgggcaggc gcttaaggcc gataagatta
     7921 aactcaccga tatggtgacg gtcggtaaag atgcctgggc gacgggaaat ccggcactgc
     7981 gtggttcatc ggtaatgttc ctcaaaccgg gcgatcaggt ttcggtggca gacttgaaca
     8041 aaggtgtgat tatccagtcc ggtaatgacg cctgtattgc gctggccgat tacgttgccg
     8101 ggagccagga gtcatttatt ggtttgatga atggttatgc caaaaaactg ggtctgacca
     8161 acactacctt ccagacggtg cacggtctgg atgcgccggg gcagttcagt accgcgcgcg
     8221 atatggcatt gctgggtaaa gcattgatcc acgatgtgcc ggaagagtac gccattcata
     8281 aagagaaaga gttcaccttc aacaaaattc gtcagcctaa ccgtaaccgt ctgctgtgga
     8341 gcagcaatct gaatgttgat ggcatgaaga caggaaccac ggcaggcgcg ggatataatc
     8401 tggttgcttc ggctacccag ggcgatatgc gtttaatctc cgtagtgctg ggggcgaaaa
     8461 ctgaccgtat ccgttttaat gagtctgaga aattattgac ctggggtttc cgcttctttg
     8521 aaaccgtgac gccaattaaa cctgatgcca cctttgtgac tcagcgcgtc tggtttggtg
     8581 ataagagcga agtgaatctt ggggcaggtg aagcgggctc agtgaccata ccgcgtgggc
     8641 agctgaaaaa cctgaaggcg agctacacgt taacggaacc gcagcttacc gcaccgctga
     8701 aaaaaggtca ggttgtcggg accattgatt tccagcttaa cggtaaatcc attgagcagc
     8761 gtccgctgat cgtgatggaa aatgtggaag agggcggatt ctttggtcgg atgtgggatt
     8821 tcgtgatgat gaaattccat cagtggttcg gcagctggtt ctcttaatct tctgataacc
     8881 ggatggcgcg aaacgtcatc cggttatacg tcattaatac atcaacttaa tacggtgcgt
     8941 ctgcgcgtac ttcacatact catcttccgg gcaacaatca ctcaccacaa tatcaaagcg
     9001 tttcaggtca cccatgcgcg ccggacgcac cttgccaaat ttactgtggt cgacaaccag
     9061 cacatgcttt tgcgccatcg acatggccca gtgttttacc ggcaactctt caagattaaa
     9121 acaggtagcg cctttactga catgcacgcc cgccgcggaa taaaaagcga tatccgggca
     9181 aaaattattc aacgtttgct gaaaatcgat gggtttgaaa atggcgttgc tggcgtgaaa
     9241 ttcaccaccg cacagaaatg cgcggcaatg gggtttctct ttcagcgcca gaaaggtatt
     9301 tagcgaataa caaacggcgg taaaagggat ttcattatca atcgcttcaa taatccacgg
     9361 cgtggtggtg ccacagtcaa aaaagagagt ctgatcgggt tctaccagtg tcgcagccat
     9421 ttttgccgcc cggcgttttt cttccaccag gcgggatttt tgatcgctta acaggtaatg
     9481 gctggcactg cgcggttcca gaacaatata gccgccgagc aaaacgacgg gcgcactgtg
     9541 gttgttcaga tcgcgacgaa tcgtcatctc cgaaacccca agcagggcgg cggcgtcttt
     9601 aagatgtaac ttatcgctgc gttttaattc ttgcagcagc tgcccgatac gctcttcgcg
     9661 acgtgtttcc ataatccctc tgaatagtta ttgaagcgag ccgctcaata ctacactttt
     9721 tagcagagat cagtcacgca cccagccttt gcggatcggt aatgcaaaac agaagcgata
     9781 ccacgattgc agacgttgat agagtttatg ccccatcgct tgccagataa tctgagcgct
     9841 aaggcagcca atcatacctg ccagcaatcc accgagcata tccagcggcc agtgcacgcc
     9901 aagataaacg cgcgaccagg caatgacgac ggccagcacc attaaaagtg agccggacca
     9961 caggcgatgc cagcataaaa atgccagtgc aaaggtgaaa atcaccgtac cgtggtcgct
    10021 tgggaatgag tcatccgccg catgatgcag gaagttatag ccgatatttt cgacaaaggg
    10081 tcggtcgtgc ggaaaaagat gtcccatcgt ccaggacaca aacaggctga ccgccagcgc
    10141 gatagcgatt tttatcacca gttgccgttg tgctgtaagc ccccacaacc aaagcaccgc
    10201 ggccagcagc ggtaccacgg taatcaaatc tttagcaata aaaatcgcca acgagatcat
    10261 ccacggagcc gagtctggcg tcgcgttaat aagagagaat agagagagat tcaaattttc
    10321 cagcataact tcccgacgca aagtgattaa aagggagcca atacaggcaa gtcgttgaga
    10381 ataaagtgca ggttaaactg ggtaaagcgg catcgtctta tttccctcaa gcggcctgtt
    10441 tacggtgggt aattgtaacg ggcataggtt aaataaaact taaagaaagc gtagctatac
    10501 tcgcaataat gtaagaatgt gcttaaccgt ggtttcagct acaaaattcg ctttctcgtt
    10561 agctgtgctt ttattaaact ctgcgcgatt attattggcg aagaaattgc atgcaaaata
    10621 aattagcttc cggtgccagg cttggacgtc aggcgttact tttccctctc tgtctggtgc
    10681 tttacgaatt ttcaacctat atcggcaacg atatgattca acccggtatg ttggccgtgg
    10741 tggaacaata tcaggcgggc attgattggg ttcctacttc aatgaccgca tatctggcgg
    10801 gcgggatgtt tttacaatgg ctcctggggc cgctgtcgga tcgtattggt cgccgtccgg
    10861 tgatgctggc gggggtggtg tggtttatca tcacctgtct ggcaatatta ctggcgcaaa
    10921 acattgaaca attcactctg ttgcgcttct tgcagggcat aagcctctgt ttcattggcg
    10981 ctgtgggata cgccgcaatt caggaatcct tcgaagaggc ggtttgtatc aagatcaccg
    11041 cgctgatggc gaacgtggcg ctgattgctc cgctacttgg tccgctggtg ggcgcggcgt
    11101 ggatccatgt gctgccctgg gaagggatgt ttgtcttgtt tgccgcattg gcagcgatct
    11161 cctttttcgg tctgcaacaa gccatgcctg aaaccgccac gcgtataggc gagaaactgt
    11221 cactgaaaga actcggtcgt gactataagc tggtgctgaa gaacggccgc tttgtggcgg
    11281 gggcgctggc gctgggattc gttagcctgc cattgctggc gtggatcgcc cagtcgccga
    11341 ttatcatcat taccggcgag cagttgagca gctatgaata tggcttgctg caagtgccta
    11401 ttttcggggc gttaattgcg ggtaacttgc tgttagcgcg tctgacctcg cgccgcaccg
    11461 tacgttcgct gattattatg ggcggctggc cgattattat tggtctgttg gtcgctgctg
    11521 cggcaacggt tatctcatcg cacgcgtatt tatggatgac cgccgggtta agtatttatg
    11581 ctttcggcat tggtctggcg aatgcgggac tggtgcgatt aaccctgttt gccagcgata
    11641 tgagtaaagg tacggtttct gcggcgatgg gaatgctgca aatgctgatc tttaccgtcg
    11701 gtattgaaat cagcaaacat gcctggctga acgggggcaa cggactgttt aatctcttca
    11761 accttgtcaa cggaattttg tggctgtcgc tgatggttat ctttttaaaa gataaacaga
    11821 tgggaaattc tcacgaaggg taaaaaaatg cctgattgct ttgtgcgatc aggcattctc
    11881 gaattaatgg tgatggtcgt caatctggtg ttcgataacc atcccttcac ctacgctggc
    11941 aagatggcga acataaggat gcgggcggta agccggagct ggcgcaggag ccacatagac
    12001 ggtttgcggc acagtcgcga cgctgaccgc ttgtggaacg ctgactgaat caggaaccac
    12061 aaccactttg tatccactcg gcacatcgac ggtgacactt tgcgccatcg ccacaccagt
    12121 aaagcccatt aaaagcgcgc ccaacagtag acaatttttc ataaacattt cgcctgaaat
    12181 aatgcagcgg gttaatttcc gcgaattatg cagccttcat tcaggtattg tgttgccggg
    12241 cgtgctgccg tttttattgg tcaaatggcg cttcgtgttt aagcacttta tcgatcacat
    12301 ccagtacgcc ttcacggtta ttggagcctg cccggtattt tgccgctgcg acgaccgcat
    12361 tgccggcatt ttccattgca aaactaaagc ctgcctgacg cagcatctca atatcgttac
    12421 cgccatcgcc aaagaccacc acttcgctgt cgtctattcc ccataatttc tgcagttggc
    12481 gaaggccatt ggctttatgt acgccgggga taatcagatc gatgctgccg ttgccggtgt
    12541 ggaccggcac cataatatcg ccgatggcct catgtaatgc tttttgtact tgtggaatca
    12601 gttcatcgga aagattcagg ccaaacttaa agaagatatc ctctaagttg tcaaagttat
    12661 cgacgtattc cagacggtga taatacattt ccgccaccgt tttcatggca tcgtcatatt
    12721 ttttgagcgt ataggcgcta ttttttccgc aggcaataat ttccacttcc gggcgcgtca
    12781 gcaaatgttc cacgacagta gtaaacgcat ccttcgacag ctcgccatta aaaacatctt
    12841 tgccttcgct cactacccag ccgccgtttt cagccacaaa ggcaatttca ttagcaattt
    12901 cagggaagaa agagatcaac tgataatatt gattcccgct ggcgactaca aagcgaattc
    12961 cttgtgcttt catttgctga tactgagcca taaaccgctc acggttatag gttttttgat
    13021 cgcttaagaa agtaccatcc atgtctaccg caattaattt aatgctcatc aactattctc
    13081 catcgccgtc tgcgttttgg tatcgggttt ggcgacggct ttcgcgacaa tagccgcgag
    13141 aataaccagc gccagtacaa ccagcattgc actacgtaat ccataatgtt cgccgagata
    13201 gcccagcagc ggcggcccga cgaggaaagc cagataaccg gtcgttgcta ccacactgac
    13261 gcgggttggt gcatcggggc cggtatcgct ggcggcagaa atggtcagcg ggaagcccag
    13321 cgaggcaccc agtccccaga gtacaacaga caccccagcg acccaggcgc tatcgacaaa
    13381 aataatcagc ccaataccca acgcccccat tagcgcactg gcccgaacca cggcaacgcg
    13441 actgtaacgg tcgatgaacc aaccgccagt gaagcgtcca acggtcatcc ccagggtaaa
    13501 accggcataa atcagcgagc cggaagtggg gctaaaaccg tgaccgtcaa ccattaataa
    13561 gggtaaccag tcgttggcag aaccttcggc aaaggccatc gccagcacca caacaccaat
    13621 cagcagcaac tggatatcgc gataaaaagg tacgcctttt tcgccatgct gggtgccatc
    13681 ggcagcattt ttgcccgtac cgtcagggat tgcctgaatg gcgatatata taggcgcgat
    13741 gcctaccagc gccgccaata aaatgtgcac cgttgccgga acgccaaagg ccgtcagtgc
    13801 catcccgaca ccagcgcctg ccagcgtgcc caggctataa aaaccgtgca tcatcggcaa
    13861 aaccgtttta ttcatttctc gctcaacggc ggcaccttca acgtttatcg ccacttccgc
    13921 agaaccaaaa cttgccccaa agacgccgag accaacggca aagagcaggg gcgatgtcag
    13981 ccagagtgcc agacttaata tcatcatccc gaccaatgcg caggacatgg tgaccaggat
    14041 gacattacgt gtcccaaagc gtttcactaa ccacgccgag cagagaatac cgctcatcga
    14101 accgatcgac agaccaaaga gaacaccgcc catttcagcg atcgagacag agagaatatc
    14161 gcggatagca ggcgtacggg ttgcccagga cgccattaac aggcctggca aaaagaagaa
    14221 cataaacagc gcccaggttc ggcgtttcaa tgcattacgt gaagaattta cggtcataga
    14281 tcacgtcaaa ataagaagag ggaagacaac attagcaagg ttgtgtacat ttgtacacaa
    14341 ttgcagagag aggaaatgac atgcgtcgcg ctaacgatcc gcaacggcga gaaaaaatta
    14401 tccaggccac gctggaggcg gtgaaacttt acggaataca tgctgttacg caccgcaaaa
    14461 ttgctaccct tgccggggta ccgttgggat cgatgaccta ctatttttca ggaattgacg
    14521 agttgttgct ggaggcgttc agcagtttta ctgagatcat gtcccggcaa tatcaggcat
    14581 tttttagcga tgttagtgat gctccaggcg catgccaggc tatcaccgat atgatctaca
    14641 gctcacaggt tgcaacgccg gataatatgg agctgatgta ccagctctac gcgctggcta
    14701 gccgaaaacc gctattaaaa acggtaatgc aaaactggat gcagcgcagt cagcaaacgc
    14761 tcgaacaatg gtttgaaccc ggaaccgccc gcgcgcttga tgcgtttatt gaggggatga
    14821 cgctgcattt tgtcaccgac cgtaagccgc tatcgcgcga ggagattttg aggatggttg
    14881 agagggttgc agggtagtag ataaatttta gataacaaaa aacccaccaa ccttgaaccg
    14941 aaatggcggg gttgatgggc tccacaaaat ggggacatca aagaaaagca gtggcactaa
    15001 ttaagactga tgccctgcgg aaaagttctg cggttgtgca aaaaaatttc attttcaggg
    15061 caacttcagt tttatcctaa tcctggccat accatgacga tgattgtccc tgccagcgtc
    15121 agcaggacgt tggcgattgc ataggtgccc gcatagccca gcgccgggat gttactgcga
    15181 gctgtatcac tgatgatctc cattgctggc gcgcaggtgc gtgcgcccat cattgcgccg
    15241 aacaacagtg cgcggttcat tcgcaataca taagcaccga acaagaaaca gataaccacg
    15301 ggcacaagac tgacaatcaa tccggcaatc aacatctgac cgccaatcgc gcccagaccg
    15361 ttattaatac cgctaccggc gctcagacca acgcctgcca taaacaccat taagccgaac
    15421 tctttcacca tgcttaatgc accctgagga atgtaaccga aggtcgggtg gttagcacgc
    15481 ataaagccca gcataattcc ggcgaataac aacccggcag cgttccccat gccgaaactg
    15541 aatgtgctga actggaatgt gatcatcccg atcatcagcc caataacaaa gaaggcgcag
    15601 aatgccagca agtcagtgac ctggctgtga atcgagataa agccgatgcg atcggcgatg
    15661 gtttttacgc ggcgggcatc gccgctgact tgtaaaacgt cacctttgtt aagcacgacg
    15721 ttgtcatcta tcggcatctc aatctggcta cgaatgacgc ggttaaggaa gcaaccgtga
    15781 tcggtcaact tcagttgtgc gagacgtttg ccaacggcgt tatggttttt aacgaccact
    15841 tcttcagtga cgatacgcat gtcgagaagg tcacgatcga aaacttcttt gccgttacgg
    15901 aagctgggat cgagtcgggc atgggcgtcg ggatagccta ccaacgctat ttcatcgccc
    15961 atttgtagca cggcatcacc gtctggattt gccagaatcc cgttacgtcg aatacgttca
    16021 atgtagcagc cggtttgtcg ataaataccc agttcacgca gatttttgcc gtcggtccag
    16081 gccaccagct ccgggccgac gcgataggcg cggatcaccg gtaaataaac cttacggttg
    16141 gcatcagtgt ccaggccacg ttcgcgggcg atttgctggg cgctggtctg taagtcctga
    16201 tgctgcaatt tcggcaagta acgcgcacca acaatcaaac tcaccagacc gattaaatag
    16261 gttaaggcat acccgaggct cagattatcc agtgccagtg agagctgcct gctttccatg
    16321 ccggaatgac gcagtgtatc gccagcaccg accagaaccg gtgtcgacgt catagagcct
    16381 gctaacatac cggccgtcag gccaatatcc cagccaaaca gcttacctaa ccctaaggcg
    16441 atcaccagcg cactgccaac catcaccagt gctaacatta ggtaattttt cccatcgcga
    16501 aaaaaaatgg aaaaaaagtt cggtccggct tcgaccccga cgcagaaaat aaacagcata
    16561 aagccaagat taagcgcatc ggtgttaatg ctgaaatgtt gttggcctaa taacagtgat
    16621 acgactaaaa cgccaatgga attacccagt tggatcgaac caagtcgtaa ctttccgaga
    16681 catagcccaa gcgcgaggac cacaaataat aacagaatgt aattcccatt taacaattcg
    16741 gcgacgttta tattcacgga ggctaacttc ttgtttacta gtaagctgtt gaaagaaatg
    16801 gtaatttacg ataatgtttt ttaccagaat tcagggcgca gattcattca gcgcacctaa
    16861 acgatagtaa agtaacaata tattttacta gtgtaatcac attaggtatc aacggctata
    16921 tgaattgcgt tggcctatat tagcatggaa tgcgaagcgg ctttatctta ctgaacgcca
    16981 cactggcgaa aaatgtgttc gatagacgca gtgtcaggag gaacgagtga aacataaaca
    17041 acgttgggcg ggggcaatct gctgttttgt cctcttcatt gtggtgtgcc tttttctggc
    17101 gacgcacatg aaaggcgctt ttcgggctgc cgggcatcct gaaatcggct tgctattttt
    17161 cattcttcct ggagcagtcg ccagcttctt ttcacagcgt agagaagtcc tgaaacctct
    17221 gtttggcgca atgctggcgg caccctgttc aatgcttatt atgcggctgt ttttttcacc
    17281 gacccgctca ttctggcaag agctggcatg gttactaagc gcggtgttct ggtgtgcgct
    17341 gggggcactg tgtttcttat ttatcagtag tttgtttaaa ccacagcaca gaaaaaatca
    17401 gtaaagccct caacgcgagg gcttgtcaga cgatcaggcg tccagatttt ctttcaccca
    17461 tgcagcaaaa tcggtatagc cgccgatatg ttgctgatcg acaaaaatct gcggcacggt
    17521 ttctacgggt ttacctgcct tttgttgtag atcttcttta gtgatccctt ccgcacgaat
    17581 atctacatac tgatactgaa aatcatcgcg ttcattgctc aatttctcag ccagatcttt
    17641 tgcacgcaca cagtaagggc aacccggacg accaaaaata acggtttgca ttatttctct
    17701 cctcatagat ttatgcctgt aatgatcacg ctaaaatgta ttcgctgaaa gtaggtttaa
    17761 cctgttgcat taattgctaa aagctataac tgttaaacac aatacagtga aaagttttag
    17821 actgaaggct cactttgcag agggaagcgt atgcgcgcga tcggtaaatt gcctaaaagc
    17881 gtgttgatac tggaatttat cggaatgatg ttgctggcgg tggcgctgct gtcggtaagc
    17941 gacaccctgt cgctgcctga gccattttct cggccagaag tgcagattct gatgattttt
    18001 ctcggtgttt tgctcatgct tcccgctgcg gtggtggtta ttcttcaggt ggcaaaacgt
    18061 cttgccccac agctgatgaa ccgtccaccg caatattcac gttcagaaag agaaaaagat
    18121 aatgacgcca accattgaac ttatttgtgg tcatcgctcc attcgccatt tcactgatga
    18181 acccatttcc gaagcgcagc gtgaggcgat tattaacagc gcccgtgcga cgtccagttc
    18241 cagttttttg cagtgcagta gcattattcg cattactgac aaagcgttac gtgaagagct
    18301 ggtgacgctg accggcgggc aaaaacacgt agcgcaagcg gcggagttct gggtgttctg
    18361 tgccgacttt aaccgccatt tacagatctg tccggatgct cagctcggcc tggcggaaca
    18421 actgttgctc ggtgtcgttg atacggcaat gatggcgcag aatgcattaa ccgcagcgga
    18481 atcgctggga ttgggtgggg tatatatcgg cggcctgcgc aataatattg aagcggtgac
    18541 gaaactgctt aaattaccgc agcatgttct gccgctgttt gggctgtgcc ttggctggcc
    18601 tgcggataat ccggatctta agccgcgttt accggcctcc attttggtgc atgaaaacag
    18661 ctatcaaccg ctggataaag gcgcactggc gcagtatgac gagcaactgg cggaatatta
    18721 cctcacccgt ggcagcaata atcgccggga tacctggagc gatcatatcc gccaaacaat
    18781 cattaaagaa agccgcccat ttattctgga ttatttgcac aaacagggtt gggcgacgcg
    18841 ctaaaaccgc cacgtcgatg tatgatacgc gggcttttga ccaggtctga cagagaggtg
    18901 cagggtgaaa attgccatat tgtcccggga tggaacgctc tattcgtgta agcggctgcg
    18961 tgaagccgct atacagcgcg gtcacctggt tgaaattctt gatccgcttt cttgctacat
    19021 gaacataaat cctgcggcgt cttctattca ctacaaaggc cgcaagttac cccattttga
    19081 cgcagtgatc ccgcgtattg gcaccgccat taccttttat gggacggcgg cactgcgcca
    19141 gttcgagatg ctggggagct atccgctcaa tgagtcggtc gccattgccc gggcgcgtga
    19201 caaattgcgt tccatgcaac tgctggcgcg tcagggcatc gacctgcctg tcacgggcat
    19261 tgcgcattcg ccggatgata ccagcgattt aatcgacatg gtcggtggtg cgccgctggt
    19321 ggtcaagttg gttgaaggca cgcagggaat tggcgtcgtg ctggcggaga cgcgtcaggc
    19381 ggcggaaagc gtgattgacg ctttccgcgg tctgaacgcg catattctgg tgcaggaata
    19441 tatcaaagag gcgcaagggt gcgatatccg ctgtctggtt gttggcgatg aagtggtcgc
    19501 tgcgattgaa cggcgggcga aagagggcga ttttcgttcc aatttgcatc gtggcggcgc
    19561 ggcaagcgtc gccagtatca caccacagga gcgtgaaatc gcgataaaag ccgcgcgaac
    19621 gatggcgctg gacgttgctg gtgtggatat tctgcgtgct aatcgcgggc cgttggtgat
    19681 ggaggtgaat gcgtcgccgg ggctggaagg aatagaaaaa accaccggta tcgacatcgc
    19741 gggtaaaatg atccgctgga tcgaacgcca cgctacgaca gaatattgcc tgaaaacggg
    19801 tggttagtcg caatcacatt actgatcatg gttttgcctg cgctttttgc gtaagctgtg
    19861 ccggtctttt tatcgaaaga ggttgtacaa aattatgaca tcgctggtcg ttcctggtct
    19921 ggatacgctg cgtcaatggc tcgatgacct ggggatgagt ttttttgaat gtgataactg
    19981 tcaggctctg catctgcccc atatgcagaa tttcgacggt gtctttgatg ccaaaatcga
    20041 tctgatcgat aacacgatcc tgttttctgc catggcggaa gtccgacctt cagccgtatt
    20101 gccgctggcg gcggatttat ctgccatcaa tgccagttcg ctgaccgtga aagcatttct
    20161 tgatatgcag gatgataatc tgccaaagct ggtggtttgc cagtctttat ccgttatgca
    20221 gggcgtaacc tatgagcagt ttgcatggtt cgtgcgtcag agcgaagagc agatttcgat
    20281 ggtcattctt gaagctaatg cccatcaact gctgttaccg actgacgatg aagggcaaaa
    20341 caacgttacc gaaaactatt ttctccactg ataattcctt tcgagcacgc agtcgctgcc
    20401 gcagtgactg cgcgctgcaa aattatctgc tgtttttaac cttttcttaa agattatttc
    20461 acttatcttg tgtcgatttg gctttatcac atagagcaaa tacgcataaa aatttgttaa
    20521 ataccgtttt ttaatccgag ctatagtctc aaaccctggc taaagttatt cttgcgatgc
    20581 ttttatatag cgagcagtgc tggccgggag agagttctct tttcttacac cgcgccgata
    20641 aaaaaatatg cacgtttatt gcatatcttt cagtgtgaca acttttgttc gtttgttaac
    20701 gaactttcag aaggaaagag atatgaccgc cttaaataaa aaatggctat cgggtctggt
    20761 tgcgggtgct ctgatggccg tctctgtcgg cacgctcgcg gctgaacaaa aaacactcca
    20821 catttataac tggtctgatt atatcgcccc tgacacggtg gccaattttg aaaaagaaac
    20881 cggtattaaa gtcgtctacg atgttttcga ctctaacgaa gtactggaag gcaaattaat
    20941 ggcgggtagc accggctttg acttggtggt tccatctgcc agctttcttg aacgccagct
    21001 gacagcggga gttttccagc cgctggacaa aagcaaattg ccggagtgga agaatctcga
    21061 tccggagctg ctgaagttgg tcgccaaaca cgatcccgac aataaatttg ctatgcccta
    21121 tatgtgggcg acgaccggga ttggctataa cgttgataaa gttaaagctg tgctgggcga
    21181 aaacgcgccc gtcgatagct gggacttgat cctcaagcct gaaaatctgg aaaaactgaa
    21241 aagctgcggt gtctctttcc tggatgcgcc agaagaagtt tttgctaccg tgttgaatta
    21301 tctcggcaaa gatcccaaca gcactaaagc ggatgattac accggaccgg caaccgatct
    21361 gctgttaaag ctgcgcccga acattcgtta tttccattca tctcaataca ttaacgacct
    21421 ggcaaacggc gatatttgcg tcgctatcgg ctgggcaggt gatgtctggc aggcgtcaaa
    21481 ccgcgcgaag gaagcgaaga atggagtgaa tgtctcgttc tcgattccaa aagaaggggc
    21541 gatggcgttc tttgatgtat tcgccatgcc tgcggatgcc aaaaaaaaag acgaagccta
    21601 tcagttcctg aattacctgc tgcgcccgga tgtagtagcg catatttccg acaatgtgtt
    21661 ctatgccaac gccaataaag cagccacgcc gctggtgagt gcggaagtcc gtgagaaccc
    21721 gggtatttat ccgcctgcgg atgttcgtgc gaagctgttc actctgaaag tgcaggaccc
    21781 gaaaatcgac cgtgtgcgca cccgcgcgtg gaccaaagtg aagagcggaa aataatccgc
    21841 agccttagat gccgggcggg cgcaccacac ccgccggcaa ttcgcaccat catggtgcgc
    21901 ttgcacacat tcaatgccgg agagcagccg tgaatgacgc tatccctcgc ccgcaggcga
    21961 aaacccgtaa ggcgctgacg ccgctattag aaatccgcaa cctcaccaaa tcctacgatg
    22021 gtcaacatgc ggtggatgat gtcagcctga ccatctacaa aggtgaaatc ttcgcgctgc
    22081 tgggcgcatc cggctgtggc aagtccacgc tgctgcgtat gctggcaggt ttcgaacaac
    22141 cttctgccgg acagataatg cttgatggcg tcgatttgtc acaggtgccg ccttacctgc
    22201 gccccatcaa tatgatgttt cagtcttacg cgctgtttcc ccatatgact gtggagcaga
    22261 acatcgcctt tggcctgaaa caggacaaac taccgaaagc ggaaattgcc acccgggtca
    22321 acgagatgct tgggctggtg cacatgcagg agttcgccaa acgcaaaccg catcagcttt
    22381 ccggtggtca gcgacagcgt gtggccctgg cccgaagcct tgccaaacgc ccgaaactat
    22441 tactgctcga tgagccgatg ggcgcgctgg ataaaaagct gcgtgaccgg atgcagcttg
    22501 aagtggtgga tattctggag cgcgtcggtg tgacttgtgt gatggtcacc cacgatcagg
    22561 aagaggcgat gaccatggcg gggcgtatcg ccattatgaa tcgcgggaaa tttgtccaga
    22621 ttggcgagcc ggaagagatc tacgagcatc caactacccg ctacagcgct gaatttatcg
    22681 gttcggttaa tgtctttgaa ggtgtactca aagagcgtca ggaagatggc ctggtgcttg
    22741 attcgccggg gctggtgcat ccactgaaag tcgatgcgga tgcttcagtg gtcgataacg
    22801 tgccggtaca cgtagcgctg cgcccggaaa aaatcatgct ttgcgaagag ccgcccgcca
    22861 atggttgtaa cttcgcggtg ggggaggtga tacacattgc ctatctcggc gatctttcgg
    22921 tgtatcacgt tcgtctgaaa agtgggcaga tgattagcgc ccagctacaa aacgcccatc
    22981 gtcatcgtaa agggttaccg acctggggcg acgaagtgcg tttgtgctgg gaagtggaca
    23041 gctgtgtggt gctgacggtt taaggagcaa agatgaatac acttgaacct gctgcccagt
    23101 cgaaaccgcc gggcggattt aagctgtggt tgtcgcagct gcaaatgaag catgggcgca
    23161 aactggtcat tgcattgcca tatatctggt tgatcttgct gtttctgctg ccatttctga
    23221 ttgtctttaa aataagcctg gcggagatgg cgcgcgctat tccaccttat accgaactga
    23281 tggagtgggc tgacgggcaa ctgtccatca ctcttaatct cggtaatttt ctgcaactga
    23341 ccgacgatcc gctctatttc gatgcttatc tccagtcgct acaggtggct gcgatttcga
    23401 cattttgctg tttactgatc ggctatccgc tggcgtgggc ggtggcgcac agtaagcctt
    23461 cgacccgtaa tattttatta ctactggtga tcctgccgtc gtggacctcg tttctgatcc
    23521 gcgtttatgc ctggatggga atattaaaaa acaacggtgt gctgaataat tttctgctgt
    23581 ggctgggggt tatagaccag ccgctgacca ttctgcatac caatctggcc gtttatatcg
    23641 gcattgttta cgcttacgtg ccgtttatgg tactgccgat ttataccgcg ttgattcgta
    23701 ttgattattc gctggtggaa gcagcgctgg atctcggtgc acgaccgctg aaaacgttct
    23761 ttactgtgat cgtgccgctg actaaaggtg ggattattgc cggatcgatg ctggtgttta
    23821 tcccggctgt gggcgagttt gtgatcccgg aactgctcgg tggcccggac agcatcatga
    23881 tcgggcgcgt gctatggcaa gagtttttca ataaccgcga ctggccggtg gcctcggcgg
    23941 tagcgatcat catgttgctg ctgctaattg tgccgataat gtggttccac aaacaccagc
    24001 aaaaaagcgt gggagaacac ggatgaataa tttaccggta gttcgttcac cctggcggat
    24061 tgtgattttg ctgctgggct ttacctttct ctacgcgcca atgctgatgc tggttatcta
    24121 ttcgtttaac agctcgaagc tggtgacggt gtgggccggc tggtcaacgc gctggtatgg
    24181 tgagttattg cgcgatgacg cgatgatgag tgcggttggt ttaagcctga caattgctgc
    24241 ctgtgcggca acggcggcgg cgatcctcgg gactattgcg gcggtggtgc tggtgcgctt
    24301 tggcaggttt cgcggatcaa atggctttgc ctttatgatc accgcgccgc tggtgatgcc
    24361 agatgtcatc acgggcttgt cgctgttgtt attattcgtc gcgcttgctc atgccattgg
    24421 ctggcctgcg gaccgcggta tgctcaccat ctggctggcg catgtcactt tttgtacggc
    24481 ttatgtggcg gtcgttattt cttcaagatt gcgggaactg gatcgctcga tagaagaagc
    24541 agcgatggat ctcggtgcga cgccgctgaa agtgtttttc gtcattacgc taccgatgat
    24601 catgcccgcg atcatttctg gctggttact ggcttttact ttgtcgcttg atgatctggt
    24661 gatcgccagc tttgtttccg ggccgggagc caccacgtta ccgatgctgg tcttttccag
    24721 cgtgcggatg ggggtgaatc cggaaatcaa cgcccttgca acgttaattc tcggtgcggt
    24781 cggaattgtc ggatttatcg cctggtatct gatggctcgc gcagaaaaac agcggatacg
    24841 cgatatccag cgtgcaagac atggctgaag acactaaaat ttgccaacct ggctacataa
    24901 tgccgcgcat gccgcggcat tgttttcatg gaagacgaaa cgttgggatt ttttaagaaa
    24961 acatcttcat ctcatgctcg cctgaatgtg cctgcgctgg tgcaggtggc ggcgctcgcc
    25021 attattatga tccgtggcct cgacgtgctg atgattttca atacgctggg cgtgcgcggt
    25081 attggcgagt tcattcatcg cagcgtacaa acctggagtt taacgctggt ctttttaagc
    25141 agtctggtgc tggttttcat tgagatctgg tgtgcgtttt cactggtgaa agggcgtcgc
    25201 tgggcgcgct ggctatatct gctgacacaa atcaccgccg caagttactt gtgggcggct
    25261 tcgctggggt acggttatcc ggagctgttc agcattcccg gtgaatcaaa acgtgaaatc
    25321 ttccatagcc tgatgctgca gaagctgccg gatatgctca tcctgatgct gctgttcgtt
    25381 ccctcgacca gtcggcggtt cttccagttg caataatgtg tataatcgtc gcccctgatg
    25441 atgtgaaggt caatgtatgc agtgcgcact ttacgacgcg ggtcgctgtc gttcctgtca
    25501 gtggataacg cagccgattc cagagcaact ctccgctaaa accgccgatc ttaaaaatct
    25561 gctcgccgat tttccggttg aggaatggtg cgcgccggtg tcaggcccgg aacaagggtt
    25621 tcgtaataaa gccaaaatgg tggtgagtgg tagcgttgaa aaaccactgc tcggtatgct
    25681 gcatcgcgac ggcacaccag aagacctttg tgactgcccg ctttatcctg cctcatttgc
    25741 gcccgttttt gcggcgctaa aaccgtttat cgcccgtgcg gggctgacac cctacaacgt
    25801 ggcgcgtaag cgtggcgaac tgaaatacat tctgctgact gaaagccaga gcgatggcgg
    25861 catgatgctg cgctttgtac tgcgttctga aaccaaactg gcacaactgc gtaaggcgct
    25921 gccgtggtta caggaacaac taccgcaact gaaagttatt accgtcaata ttcagccggt
    25981 acatatggcg attatggaag gggagacgga gatctacctt actgaacaac aggcgctggc
    26041 agagcgtttt aatgacgtac cgctgtggat ccgtccgcaa agtttcttcc agactaatcc
    26101 ggcggtcgcc agccagctgt acgctaccgc gcgcgactgg gtacggcagc tgccggttaa
    26161 acatatgtgg gatctgttct gcggtgtggg tggctttggt ttacactgcg cgacgcctga
    26221 catgcagtta accgggatcg aaattgcatc agaggccatt gcctgtgcaa agcagtcagc
    26281 cgctgaactg ggcttaacgc gtttgcaatt tcaggcgctg gactccactc agtttgccac
    26341 cgctcagggg gaggtgccgg agctggtgct ggttaatccg ccgcgccgcg gcattggtaa
    26401 accgctatgt gattatctct caacaatggc accgcgtttt attatctact ccagctgtaa
    26461 cgcccaaacc atggcgaaag atatccgcga actgccaggt taccgcatcg aacgggtaca
    26521 gctttttgat atgttcccgc acaccgcgca ctatgaagtg ctgacgctgc tggtgaagca
    26581 ataaaaaagc cgcaggtgcg gcttcagatt gctgatcagg tgcgctttgt tcatgccgga
    26641 tgcggcgtgt acgccttatc cggcctacaa aatcatgcta aatcaataca ttgcagagtt
    26701 gatgtgggcc ggataagcgc agcgcatcag gcaatcttac ttttgtcatc agtctcaatt
    26761 actgcggaaa ccactggtca ttgattttct gatatgtacc gtcagcttta attgctgcca
    26821 gcgcgttatt cagtttttcc agcagagctt tgttatccgg acgtacagcg atgcccagac
    26881 cggtgccgaa gtattgcgga tcggtcactt tttcagtagc aacgcccagt tgcggattgg
    26941 ttttcagcca ttcgtttacc accgctgtgt caccaaatac cccatcaata cgaccatttt
    27001 tcagatcgat aaaggcattc tgataactgt cataggagac agttttcact tcggggtgct
    27061 gatcctgaat atatttctgg tgcgtggtgc cgttttccat cccaatacgt ttgcctttca
    27121 gatcggcaaa cgttttgtag gtatcttttt tggcaatcac gacggctgag ttttcatagt
    27181 agggcgtggt aaacgatacc tgcttgctac gctcgggcgt gatatccata ccggagatta
    27241 cggcgtcata ttttctgaat ttcagtgacg ggatcaggct gtcgaacgcg tgattagtaa
    27301 aagtacattc tgcctgcatt tgtttgcaca aggcttttgc cagatcgata tcaaagccga
    27361 caatctcatt attagcacct atagattcaa agggtggata ggtggctgaa acgccaaaat
    27421 tgattttctc tgcggcagaa gcaccgaaag taaaggaagc aagtaaagcg gcaagaacta
    27481 actttttcat gatggaactc ccgtctgtca atcttatgat ttttggccgt gtctgcggca
    27541 tgggataaca atgccatcaa gtgaatttat atgcaataaa tatgattaaa taatttaaat
    27601 gaaataaaaa aagacggata ccttagtgag ttgtccgtct tcattataag aatttatgca
    27661 ctatgtaggc cggataaggc gtccacgccg catccggcac aggcaccgtg ctgatgtctg
    27721 atgcgacgct ggcgcgtctt atcagaccta caaacccccc cggcgaatgt acgcagctac
    27781 attaatttcg ccgttcgaat gccagtgctt tgcgctcgat cagacgcatc atcagcgtca
    27841 gcaggccgtt gacgaccagg taaataatcc ctgccgcacc gaacaccatt acatcgtagg
    27901 tgcgtccgta caacaactgg ctgtatccca tcacttccat cagcgtaatg gtgtaagcca
    27961 gagaggtact tttgaacacc agcaccactt cgttggaata agaagagagc gagcgtttaa
    28021 aggcatacgg cagcaggatc gccagcgtat cttttttgct cattcccagg gcgctacagg
    28081 actgccactg accttctggg atcgcacgaa ttgcaccgta aaacagctgc gtggtatacg
    28141 ccgcactgtt cagcgataac gcaatcagcg cacataacca cggttctgac aacaaatgcc
    28201 acagtgccgg atactcctgc aaagtcggaa actggcccgg cccgtaataa atcaggaaga
    28261 tctgcaccag cagcggcgta ccggtaaaca gcgtgatata accccgcacc agccacacca
    28321 gcaccggcgt tttcagcgtc aggatgatgg taaaaatcaa tgccagaatc agtgccacaa
    28381 tcagcgaggc aacggttagc gtcaggctgg tgtgtagccc tttcatcagt tcgggtaaat
    28441 actcaaacat tagctgggcc tccgctcaaa acgtgtcgcg cgcaggtcaa tgcgtttgag
    28501 aatgtactga ctgagcaggg tgatcaccag gtaaatcgcc gccgccacaa tgtaccaggt
    28561 aaatggttcc tgggtacgag tagcgatgct ttttgtttgc agcattaaat cattcacact
    28621 aatcaaactg accagcgcgg tatctttcag cagcaccagc cactggttac cgaggccagg
    28681 cagcgcatga cgccacatct gcggcatcac cagacggaaa aagatagccg atttcgacag
    28741 ccccagcgcc tgaccagact cccactgacc caccggcacc gctttcaacg cgccccgaag
    28801 cgtttgcgag gcataggcgg catacagcag tgacagagcg atgacaccac aaaggaacgg
    28861 gctaacgtcg aagttctcaa tgtccatctg cactgggatc tgcacgaacc caagattgat
    28921 agtgaagcca tccgaaagcg tcagcagcag ctgcgaggag ccaaaataga taaacagcac
    28981 caccagaatt tctggcaggc cacgcagaat ggttaccagc gctgaacctg cccacgcgac
    29041 aggacgccat tttgccgact cccataccgc aaagaacatc gccagcgcca gcccgacaat
    29101 caatgcacaa acggcaaggc cgacggtcat cccggcggcg cttgctaaag gaaaaaattc
    29161 attcatcagg aattacttct ggaaccattt gttgtagatg gtttcgtaag tgccatcttt
    29221 cttcactttt tccagcgcag tgttgagttt ctgctgcagc tcagtgttgc cctgacgtac
    29281 cgcgatgccg aggccagtgc cgaagtaatc tttatcggtc actttgtcgc ccaccgccgc
    29341 cagtttcggg ttatctttca gccactcagt gaccactgcg gtatcaccga agacgccgtc
    29401 gatacgcccg ttttgcagat ccagttttgc gttctggtag ctgtcatacg gaacggtagt
    29461 gatttccggg tgcttatcca taatgaattt ctggtgtgtc gtcccgttct gaacgccgac
    29521 ttttttgcct ttcagctgat caacactggt gtatttgcct tgctgaccca caaacagggc
    29581 agagttgtca tagtacgggg tggtaaacag tacctgcttt tcacgctccg gagtgatatc
    29641 catgcccgcc atcactgctt ctacgcgacg gaatttcagg cttgggatca ggctgtcaaa
    29701 cgcctggtta gagaaagtac aggttgcatc aatctcttta cacagtgcct gtgccaggtc
    29761 gacgtcaaaa ccaacgatct ggttgtttgc atcaatcgat tcaaacggag gataggaggc
    29821 ttcggtagca aaacgaatgg tttcggcagc tgtggcggaa agactaaaac ctgcaattaa
    29881 cgcggcaatc agaacttttt tcattgttgt tatcccgaat cttagtgaga gagatagttt
    29941 ttaaatgctt cggtttgcgg ctcggtaaag cagctcgcgt cgccttgttc tacgatatga
    30001 ccattttcca tatacaccac tcggctggcg gttttacgcg ccacttcaac ttcgtgggtg
    30061 acgatcacct gggtaatatt cgtttctgcc agctcacgaa tgatgctgac gatttgtgcc
    30121 gtaatttccg ggtccagtgc ggcggtcggt tcatcgaaca gcagtacctg cggttccatc
    30181 atcaacgcac gggcaatagc aacacgctgc tgctgaccac cagaaagatg cagcgggtaa
    30241 cgatcgctat aaggtttgag acgcagacgt tccagcagtt tttctgcacg ggccagcgcc
    30301 tgatctttac tcaaccccag tacacggcag ggcgcttcaa tcaggttttg ctgcacggtc
    30361 agatgcggcc acaggttgta ttgctgaaac accatgccaa cgttacgacg caaatcgcga
    30421 atcgctttgt cagagggtgt tttggtgaaa tcgaaatggt tgcctgcaat gttgagcgta
    30481 ccggagcgcg gcatctcaag cagattgagt acacgcagca gcgagctttt acccgcgccg
    30541 ctggggccaa gtaacaccag cgtttcgccc tgtgggcaat ccagcgtgat atcgaacagc
    30601 gcctgatgcg cgccgtagaa gcaattaatg ccgtttaatt gaatactcat tgacactcgt
    30661 atactggcag tctgatagct attgaggtcg aagatagtac ctttgacaga ataattatgc
    30721 aatatttctg ctttaaaagt taaaagcaaa gcgcattatt caataaacat agcacaaaat
    30781 aacgggggcg gtggtcggtg agcataaatg tcggcattcc tcacgaaatg ccggacaatt
    30841 tacggggttt attggttgat caaggcgtta gcgattctcg atggactgac ggagcgtacc
    30901 cgctgtggca tgaacgctgc cgcctaaata gcgtacatcg tcgatcaccc aacactggcc
    30961 ttcctgaatc attaacactt catcctgcca gctctgatca ccctgtttta gatccacacg
    31021 cagaggaata tttcgcgcat cacgattcgg gattgttgag gcactggcaa cacgggcgct
    31081 ctctggcaag gttgtgcgac tggagaatgg atcgttggtc agtagttccc gatggttatt
    31141 atcccgggag gcatcgctaa gcagtgtcgc cagtttgtcg ctcagataag ggcgcaaggc
    31201 ggtgatgtcg ttgctgcggt gcaaaatgcg gtagtcataa aattgctggg ccacgttatc
    31261 cgggcctcct tcaacgcaag gaccactgcg tgtgccgtta tctttataag ctggagtgac
    31321 tgtggtgcag gcactgagga gcagtgcgca ggggataagc attgtcaatt tgctgtagcg
    31381 cataatgatt tccttataag cgatcgctct gaaagcgttc tacgataata atgatatcct
    31441 ttcaataata gcgtatcagt ctgataatgc tttagagatc gaaggcttaa caaacaagga
    31501 gatcgatcat gcaattttct acaaccccaa ctctggaagg ccagaccatc gttgaatatt
    31561 gcggtgtggt gaccggcgaa gcgattttag gtgccaatat tttccgtgat ttctttgccg
    31621 gtatccgcga tatcgttggc ggacgttccg gtgcgtatga aaaagaactg cgtaaagcac
    31681 gggagatcgc ctttgaggaa ttaggctccc aggcgcgggc gctgggggcc gatgccgtcg
    31741 tcggtattga tatcgactac gaaacggtcg ggcaaaacgg cagtatgctg atggttagcg
    31801 tcagcggtac ggcggtgaaa acgcgtcgat gagaagagtc ttctggctga tcgctgccgc
    31861 tctgttactg gcagggtgtg caggcgaaaa aggcattgtc gagaaagagg gatatcagat
    31921 tgatacccga cgccaggcgc aggcggcgta tccgcgcatt aaagtgctgg tgatccacta
    31981 caccgcagat gattttgata gctcgctggc gacactgacc gataagcagg tcagctcgca
    32041 ttatctggtc cctgcggtac caccgcgata caacggtaaa ccgcgcatct ggcaactggt
    32101 gccggaacaa gaactggcct ggcatgcggg gattagcgcc tggcgcgggg caacgcgcct
    32161 taacgacacc tctattggca ttgagctgga aaaccgtggc tggcaaaaat cggccggagt
    32221 gaaatatttt gccccgtttg aaccggcaca gattcaggcg cttattccac tggcgaaaga
    32281 tattattgcc cgttatcaca tcaagccgga aaacgtagtg gcacatgcgg atatcgcacc
    32341 gcagcgcaaa gacgatccgg ggccattatt tccctggcag caactggcgc agcaggggat
    32401 tggtgcctgg ccggatgcgc agcgggttaa cttttacctt gccgggcgcg cgccgcacac
    32461 accggtagat accgcgtcat tgctggagct tttggcgcgc tacggttatg acgttaaacc
    32521 tgatatgaca ccgcgcgagc agcggcgcgt gattatggca ttccagatgc atttccgccc
    32581 gacgttatat aacggcgaag cggatgcaga aactcaggcg attgccgaag cattgctgga
    32641 gaaatacggg caggattagc gcggcagttt tccgtggtcg cgtagccagg cggcagtttt
    32701 ctcgatacct tcatccaggg tgatgaccgg ctgataacct aactcttcct gcgcacgcgt
    32761 aatatccagc gtaaagtcaa aattcaactt ggagacgccg tagtgggtca gcggcggctc
    32821 ttttgctgac ttgcggccta aacgctccat gctgcgggcg atcatatcca gcatcgggta
    32881 ggggacggaa cgaatacgac agtcaatatt caactcgtcg atcagcttct gcacgatgct
    32941 gcgcagtgtg cgatgctcgc cgttggtgat gttgtacaca cgcccggaag gtagcttatc
    33001 gcaggcttcc tggcttgcca gccacattgc gtgcacggca ttttcatagt aggtcatatc
    33061 gaccagcgca ctgccgccat gcggtaacag aatactgccg tagtggtgca tcatatgcgc
    33121 cagacgggga ataaagactt tatcgtgcgg tccgaacaga ctttgtgggc gcagaatagt
    33181 aaagcgcgtt tgtggattcg cctgcgaaag catattgatc acttcttcgc tggctgcttt
    33241 gctgcgggca aactcgttgg cgaagcggtg agggcgaaaa tcttctttaa tatcgcgatg
    33301 gtggtgataa tcgaagtaca gggaggggga agagatatga ataaagttac gcacacccca
    33361 ggcgacagcc cattcaccca ggcggcgagt ggcgcgaacg ttagccagat cgaaagcctg
    33421 ttgtgtcccc cagggtgagg taaagctgga gcagtgccac agcgtatcaa tgcccgcgag
    33481 catcacttta gcttgtgatg aaaccagctc ggtcagatcc gccggaacaa actctgcgcc
    33541 cattttttcc agcaatttgc ccattgcctc gttgcgaccg gtcgctcgca cgctgatgcc
    33601 tttctggcat aaaaactcta ccgcgtttcg acctaagccg ctggtggcgc cggtaaccag
    33661 taccttcata tcaatccact gttgttgaga aaataacgtg cgcattcttc cgtgatttcc
    33721 cccatgatgc aatgggaaac atgaaagaat aacgcaggtt ttgtcgatta atctgtgctt
    33781 tgttctgcca gtctggcgat ttgttttgcc attccgcgaa aaataaacag atgcgcgggg
    33841 atcatcaata accagtaaaa cagccccggc ataccgtgcg gatgccagaa agcgcggaca
    33901 tcgatagtac gatagtcgcc tttatcttcc aggctaaaac acagtcgtcc cagccccggc
    33961 gctttcatgc caaataacaa cgtaagttgt ttttccggtt caacgacaat cactttccag
    34021 ctatctaccg catcgccagt ctgtaaatat tcgcgctccg ggcggccttt cgccagctta
    34081 tgaccgatcg cgcggtccat caacgcccgt gtctgccaca aaatattgcc aaagaaataa
    34141 cgctctttac cgccgatttg gttcactacc tgccataaag cagcaaggct ggcggacgtt
    34201 ttaacggtaa accccgcctg tttggcaaaa taaccgtact ccggtcgcca gcgggcaaag
    34261 gcctgagcgt cgtagcccca gtcgctggag ttgaccagtt tttcctcctc tttcaacgtg
    34321 ctacgtaccg cgtcatcgaa agcgatcagc cgttgtggga tgagtgcacg tagcgcggta
    34381 tcatccgcca gcagatcgtg tttcagcccc tgaatcaacg ccctggcggt ggtgggcggt
    34441 acggaagtaa tcacattgag aaaccacacc gaaatccagc gggtggggag ggggatgggg
    34501 atcaaccagc ggcgcttacc gctcaccgcc ataaaatgtt caaactgttg ctgataactg
    34561 agcacctctg gtccggcggc ttcgaagatg cggtgttcgc tggccggatg atctaacaac
    34621 gccaccagat agtgcagcaa gttttccagc gcgatgggcg tggtgcgtga acgtacccag
    34681 cgtggcggcg ttaacactgg caggttgtag accatatcgc gcatgacttc gaacgccgct
    34741 gaacctgcgc caacgataat tccggcccga agttcggtca caggtacatt cgcttcacga
    34801 agaatgtccg ccgtagcctg acgagcacgc agatgatccg actgctcatg tggcggggcc
    34861 tgcaacgaac tgagaaagat taattgctta actggtactt cacgtagcgc atcgcggacg
    34921 ttgagagcca cctggcgctc ctgagcgata aaatcgccgc cttcgcccat gctgtgcacc
    34981 agaaaataga cggtatcgat atcctgcaac agggccggaa ggttatccgg ccagctgaga
    35041 tcgactttat ggcaactgac gtttgccagt tgcagctttg caagcctgtc gacatgacgt
    35101 gccgccgcca ggatctgatg cccttgctgg ctgagtgtgc gcaccagatg ctgaccaatg
    35161 tagccactgg caccgagaac taaaatgcgt tgcggcacgt ctctctcctt aacgcgccag
    35221 gaatgcgcgc cagtgggcgg cgacttccgc cagttgttcg cgcgagacgt caagatgcgt
    35281 caccaggcgg acaatcggcg aggcgttaat cagcacgttt ctcgctttca tgtattcgcc
    35341 taacgcggca gcattttctt ccccgacgcg aacaaacagc atattagtgt cctgacgcat
    35401 cacatccgcg cctgcttcac gcagttgctc cgccatccag gcggcgttgt cgtgatcttc
    35461 ctgcaaccgt gcgacgttat ttttcagggc atacatcccg gcggcagcca gaatcccgga
    35521 ctgacgcatc ccgccaccgg ccattttccg ccagcggatg gcacgtttaa tgtaatcacg
    35581 attaccgacg agtaatgaac cgactggcgt cccaagacct ttcgacaggc aaatggtgaa
    35641 cgaatcacaa tattgcgtga tctctttcag ttcgcagccg taagccacca cggcattaaa
    35701 gatgcgcgca ccgtcaacat gcagcgccag attgcgctcg cgggtaaatt cccatgcttc
    35761 tttcaggtat tcacgcggca gcactttgcc gttgtgggtg ttttccagac tgagtaattt
    35821 ggtgcgggcg aaatggatat cgtcgggttt gattttcatc gccactttat ccagcggtag
    35881 cgtgccgtcg gcagccgcgt cgatgggttg cggctgaata ctgcccagca ccgctgcgcc
    35941 accggcttca aacagatagt tatgcgcggc ctgaccgaca atatactctt cgccacgttc
    36001 gcagtgactg agcagagcga ccaggttggc ctgagtgccg gtaggcagaa aaatggcggc
    36061 ttctttaccg gaaagctctg ctgcatagtc ctgcagagca ttaacggtag ggtcgtctcc
    36121 gtaaacgtcg tccccaaccg gggcggccat catcgcttcg agcatggcgc ggctcggtcg
    36181 ggtaacggta tcactgcgta aatcaatcat ggcatgtcct tattatgacg ggaaatgcca
    36241 ccctttttac cttagccagt tcgttttcgc cagttcgatc acttcatcgc cgcgtccgct
    36301 gataattgcg cgcaacatat acaggctaaa acctttggcc tgttcgagtt tgatctgcgg
    36361 tggaatggct aactcttctt tggcgaccac cacatccacc aacaccggac cgtcgataga
    36421 gaaggcgcgt tgcagggctt catcaacttc agacgctttt tctacacgga tacccgtaat
    36481 gccgcacgct tcggcaatgc gggcaaagtt tgtgtcgtgt agttcggtgc cgtcagtcaa
    36541 atagccacca gctttcatct ccatcgccac aaagcccagc acgctgttgt taaagacgac
    36601 aattttcact ggcagtttca tctgcactac tgagaggaaa tcgcccatca acatgctaaa
    36661 accgccatcg ccgcacatgg cgaccacctg acgttctggc tctgtcgcct gcgcacccag
    36721 cgcctgcggc atggcgttag ccatcgaacc gtggttaaac gaacctaaca ggcgacgctt
    36781 gccgttcatt tttagataac gtgccgccca caccgttggc gtaccaacgt cacaggtgaa
    36841 aatagcgtca tcggcggcaa aatgactaat ttgctgcgcc agatattgcg ggtgaatggc
    36901 tttctcgctc ggtttagcta aatcgtccag ccctttgcgg gcgtcgcggt aatcttccag
    36961 cgctttatcc agaaacttgc gatcggcttt ttcttccacc aatggaagca atgcacgcag
    37021 agtcgacttg atatcgccga ccagtgccat atccaccttg ctgtgagcgc cgatgctggc
    37081 tgggttgata tcaatctgaa tgattttggc atcggtcggg tagaaggcgc ggtagggaaa
    37141 ttgcgtgccg agtagcacta acgtgtcggc gttcatcatg gtatggaaac ctgacgagaa
    37201 gccgattaac ccggtcattc caacatcata cggattatcg tattcgacat gttctttacc
    37261 gcgcagggca tgaacaatag gcgctttaat tttcccggca aactcaacta actctttatg
    37321 cgcccccgcg cagccgctgc cacacatcag ggcgatattg ctggaataac gcagcagttg
    37381 cgccagtttg cgtaactctt cttcttccgg cgtcacgact ggttgtggcg catgatacca
    37441 gtgcgtggtt gccccttctg gcgcaggttt taacgccacg tcgcctggta acacgacaac
    37501 cgaaacgcca cggttaagca ccgctttgcg catggcaatc gccagtactt gtgggatctg
    37561 ctccgggctg gaaaccaact cgcaatagtg actacattcg cggaatagct cttgtgggtg
    37621 ggtttcctgg aaatagccgc tgccaatttc gctggaggga atatgagcgg caatcgccag
    37681 taccggaacg tgattgcggt ggcaatcgaa caggccgttg attaagtgca ggttgccggg
    37741 gccgcacgat ccggcgcaga ccgccagttc tccgctaagt tgtgcttcag cgccagcggc
    37801 aaaggccgcc acttcttcgt ggcgggtgga catccactcg atggtgccca tgcgattaag
    37861 actgtcacta agaccgttca gagagtcgcc agtgactccc cagatgcgtt tcacccctgc
    37921 cgattcgagt gttttggcga tataagctgc aaccgtttgt ttcatggttc tccatctcct
    37981 gaatgtgata acggtaacaa gtttagttca tctgacggag ggggaaggga tgggagagaa
    38041 aggaggcact aacggttaaa tagcccgatg aaaggaatat catcgggcat aaggcgatta
    38101 tgcgagaacc aaatccccct gcggatggca ggagcaggcc agtacgtaac cttcagcgat
    38161 ttcggcgtcg gtcagcgtca ttgtactgct caccgtatat tcaccggaaa ccacttttgt
    38221 cttacagcag ccgcaaacac ccgcacggca ggcagcgaca accggaacgt tattgctttc
    38281 cagcgcctcc agtagtgtgg tgccaaccgg ggcgtaaaat tctcgtgccg gttgcagttt
    38341 ggtgaatttc agaccgctgg tcgccgcttc tgctactggg gtgaagaatt tctctttaaa
    38401 gaaacgcgtc acgccgagcg ctttcacttc ctgctctacc caatccatat acggagccgg
    38461 gccgcaggtc atcacggtac gtgaagctaa gtcaggtaca cctgccagca gttcgcgagt
    38521 gagacgacca gcgataaagc cttcggtaac gttattttct gccaccagcg ttaccggata
    38581 gttacgccac tcatcggcga aaataacatc ctgcggcgta cgcacgttgt agatcacccg
    38641 cacatcggcc tgtggacggt tcttcgcaag ccagcgacgc atcgacataa tcggcgtgac
    38701 gccgcagcct gccgccagca acaggaattt atcttctgct ttatcgtcgc aggtaaattc
    38761 ccccatcgcg tccgaaagcc agagataatc accgcgtttt acatcgcgcg tcagccactg
    38821 ggagccgaca ccgtcatcaa tccgccgcac ggtcagggtg atatattcac tcacgcctgg
    38881 cgtggaggaa atggtgtaag cacgcagcgt ttccgctgag tttcgcacgc tgaccagtgc
    38941 atattgcccg gcgcgatatg ggtagtaatc gtggcaaatc agggaaatcg tccacacatc
    39001 cggcgtttct tgcgtaatgt gatgaacctg catccgccac gggcattgat tcgttggcat
    39061 cgtcatcgac aaactcctta cgcgctcaac agttgcttca tgtcttcttc aacagtggtg
    39121 atagaacgca ggccaaattt ctcgttcagc accgccagca ggtctggtgt caggaaacca
    39181 ggtgcagtcg ggccggtgac gatatttttc acgcccagag aaagcagcgt cagcagaatg
    39241 acgatcgctt tctgttcaaa ccaggagagc accagcgaca gcggcagatc gttgacaccg
    39301 cagcccagtt tctctgccag agtgacagcc agaataatcg ctgagtaagc atcgttacat
    39361 tgacctgcat ctaccagacg cggcagacct tcgatatcgc caaactcaag tttgttaaag
    39421 cgatatttac cacaggcgag ggtcaggatc aggcagtcat ccggcacgct ggtggcgaaa
    39481 tcggtgaagt agtggcgctc gccgcgtgcg ccgtcacagc caccaagcag gaagatatga
    39541 cgcagttttt cacggctcac cagatcaatc agcgtatcag cagcgccaag cagcgtctgg
    39601 cgaccaaaac ccacggtgat caggtgcgga atttcgctgt acgggaagcc cgccatttgt
    39661 tgcgcctggg cgatgaccgc agaaaaatct tcgccatcca gatgacgcac acccggccag
    39721 ccaacgatgc tgcgggtcca gatacgatcg tcataagcgc ctacggttgg gtcgatgatg
    39781 cagttcgagg tcatcacgat ggggccaggg aaacgagcga actccacttg ctgattctgc
    39841 cagccactgc cgtagttacc gaccagatgc ttgaatttac gcagctccgg gtagccatgc
    39901 gcaggcagca tttcgccgtg ggtgtagaca ttaacgcccg tgccttcggt ctgttccagc
    39961 aggttgtaga gatctttgag atcgtgaccg gaaatcagaa tgcatttacc cgccgtcgct
    40021 ttgacgttga cctgggttgg cgtcgggtga ccgtatttac cggtttcgcc tgcatccaga
    40081 atgctcatca ctttgaagtt catctggccg atttccattg aacactcaag aagcgcgttc
    40141 atatcggcag gccaggtccc cagccacgcc atgattttat ggtactgggc ataaatatcg
    40201 ttgtcgtatt gaccgagaac atgcgcgtgt tccatatagg ccgccgcacc tttcaggcca
    40261 tacaggcaca gcagacgcag gccgagaatg ttttcgccaa tcgccgcttt atctttgtta
    40321 ggggtaaatt ctgctgcctg acgttgcagc tcgccgagat cgtcgctcac cagttgcagg
    40381 tcagccatcg ggttatcgac gcgcgcgttg gcatctacag ccaggcattg cgctttcagc
    40441 gcctcgcgca gggcaatcgc ttcacgagcg tagccgacaa tacgcggaga atcgaagtta
    40501 acgttggtca gggttgagaa aaaggcacgt ggcgcgaagc tgtcaacatc gtggttgatg
    40561 atgccgtatt cacgcgcttt taccgcccag gcagaaagcc cttgcagcgc cgcgatgagt
    40621 aaatcctgaa ggtcagaagt ttccgccgtt ttaccacaca tcccctgcgc gtatgagcag
    40681 ccgtttcctg ccggagtacg gatagtttgt tcacattgca cacaaaacat gatcacacct
    40741 tttaaagtta tatttaatat acatgtttaa ggttaagacg cttaacgcgg ggataaaagg
    40801 gatttttcat gcaactttaa gggagattga tttagcgcaa ttttggcggc agggatctac
    40861 cgccagagag gtattacgca gagaaaaagg cgatgaggat cggcactaac aggctaagaa
    40921 taaaaccgtg aacaattgcc gccgggacca tatccagccc gccagtacgt tgaagaacgg
    40981 gcagggtgaa atccattgat gtggcaccgc ataagcccag tgcagtagag cggctgcggc
    41041 gaatcagccc agggatcaac ataatagcaa tcagttcacg ggccagatca ttaaaaaacg
    41101 ccgcgctccc gattaccgga ccaaaagatt cggtcaataa aataccggaa agagaatacc
    41161 agccgaaacc ggaggccatt gccagcgcgg tattgatggg gagatcaaga ataaaggcgt
    41221 taattaaacc accaattaat gaactgacaa ccaccaccac ggcgacaatc attccccggc
    41281 gattaaggac aatctgcttt aaggtcatgc cattattgcg caactgaata ccaacgagga
    41341 aaagtagcaa aattaacgtg tattcactgg cttcggtcgc gtgttgtaag aaagccagtc
    41401 cactcagacc aatggcaaaa ccaatcacta ctacgccgca cagttttagc gactccagcg
    41461 ccatcgcaat acgcgacggg agtttttctt gctgatggtg gttgcgccac ggcaggcctc
    41521 gctccagcca catcagggcg gcaatattac acagtaaaat aacggtaata ctgacggcag
    41581 aataatgcag aatcgccaac aggttactgg cgaggttatc gagaaacgcc agactgatac
    41641 ccataaaaaa gagaataagg taaaccatcc agcttaatag ctgattaata acttttaacg
    41701 cagcttgttg gcgaagcgga atgaggtaac ccacaatcag gggaaccaga atgattaaca
    41761 gcccagaaaa catgaaaacc cagtccttgc aaagatgaag tcgaaatgcg cgatgacaca
    41821 ctactgaaag cggaaggacg agtaaagttg caattaaaag gaaatgttat gcataaggag
    41881 cagtagagta ttcgttttca tttaaagata ttcttgcgct ttaattacaa actgcaccga
    41941 tgttggtggc gtcaaaatcg ccgaggcgtt ccctgaaggc cggggcagcc cacatggatg
    42001 tgggctgagg gcgcgtttta cagggatgtt acctcgcgcc cgacccggta gccgtaaggg
    42061 ataagtcgag ggcaccgcgc agcggcgatt ttgttcgcca gagcccgggg gtgcaggggg
    42121 cggcggcgat tggccgcccc ctgcgcgctc cttgcgccag tggcaatatg tggcttagct
    42181 catgaaagga gcgcaacaag atgatgaatc aacatataac aacatcttaa aaaaaggcct
    42241 gacattacgc caggccttct gcgttaatta atcacgcttt tccagcaggg tccggtaaat
    42301 cagaccaccg ataatgccgc cgacaattgg caccacccag aagaaccaca gttgttctaa
    42361 tgcccagccg ccctggaaga tagcaaccgc ggtgctgcgc gccgggttaa cagaagtgtt
    42421 agtcaccgga atactaatta agtgaatcag ggttaaggcc agaccaatag cgatcggcgc
    42481 aaaacctgcc ggcgcgaatt tgtcggttgc gccgtggatc accaacagga aacctgcact
    42541 caataccagt tcaactacca gcgcggaaag catggaataa ccgcctggtg aatgctcgcc
    42601 ataaccgtta gaagcaaaac cgctggctgc cgcgtcaaaa cccgttttac cactggcaat
    42661 taaatacagc agcgccgctg caacaatacc gccgacaacc tgggcaatta cgtagccaac
    42721 gacttctttt gccggaaaac gtccgccagc ccataaacca atagtgaccg ccgggttaaa
    42781 atgaccacca gaaatatgac caacagcaaa ggccatcgtc agaacggtca gaccgaacgc
    42841 caacgccacg ccggcaaaac caatgcctaa ttccgggaag cctgcggcca gtacagcact
    42901 accacagcca ccaaaaacaa gccagaaagt accaaaacat tcagctgcta attttctgaa
    42961 catatccacc tcaattaaaa attgaccctg tgaaaaatat ggtcgtttta tagggtcgtc
    43021 gtaaaaaagt gacgacggaa ataatgcgcg gctattttaa aaacgaaggc gagtcattca
    43081 ccagataaat aaatccagta aatttgattt agggcaacag cgggttgccc catatagtca
    43141 tttgtctgat tgacagtgta gtgcaagcaa aagatttaat cctttaggcg taataaaaaa
    43201 taatttatca tgctaattat ttgattttgt tgtttttgca gacttatcag caagagggag
    43261 tataacgcga ttattcgctc atttttcaga catttgccat gcttaaatgt gatgtcatca
    43321 cgtattagca aggcctttcc cgttatactg ccagcgtaaa ggataagtca catatttctg
    43381 gaggggatat gattcttgag cgcgttgaaa ttgtgggttt tcgcggtatc aaccgtttgt
    43441 cgttgatgct ggaacaaaac aacgtcctga ttggggagaa cgcgtggggt aaatccagct
    43501 tgctggacgc cttaaccctg ctgctatcgc cagaatcaga tctctaccat tttgagcgcg
    43561 acgatttctg gttcccgccg ggagatatca acgggcgaga acatcatctg catattattt
    43621 tgaccttccg cgaatcgctg ccaggccgac atcgggttcg ccgttatcgg ccgctggaag
    43681 cgtgctggac gccatgcacc gatggctatc accgtatttt ttatcgtctg gaaggggaga
    43741 gtgcggaaga cggcagcgtg atgacactgc gcagttttct cgataaagac ggacatccga
    43801 ttgatgtcga ggatattaac gatcaggcac gccatctggt gcgtttaatg ccggtgctgc
    43861 gcttgcgtga tgcccgtttt atgcgccgta ttcgtaacgg cacggtgcca aatgtcccca
    43921 atgtggaagt caccgcgcgc cagctcgatt tcctcgcccg tgagttgtcc tcacatccgc
    43981 aaaatctctc tgatggacag attcgtcagg gactttccgc aatggtgcag ttgcttgagc
    44041 attatttctc tgagcagggg gctggacagg cgcgatatcg tttaatgcgg cggcgggcca
    44101 gcaatgagca acgaagctgg cgctatctgg atatcatcaa ccggatgatt gaccgacctg
    44161 gagggcgctc gtatcgggtt attttgctcg gcctgtttgc aactttattg caggcaaaag
    44221 gcacattgcg actggataaa gacgcccgtc cattgttgct gattgaagat ccagaaaccc
    44281 gtttacaccc cattatgctt tcagttgcct ggcatctgtt gaatcttctg ccattgcagc
    44341 gcattgccac caccaactcg ggtgagttgc tttcgttaac tccagtggaa catgtttgcc
    44401 gcctggtgcg tgaatcttct cgtgttgccg cctggcgtct ggggccaagt ggcttgagca
    44461 ccgaagacag ccgccgcatc tcttttcaca ttcgttttaa tcgtccgtca tcgctgtttg
    44521 ctcgctgctg gttgctggtg gaaggggaaa cagaaacctg ggttatcaac gaactggcgc
    44581 gccagtgtgg acaccatttc gatgccgaag ggatcaaggt cattgagttt gcccagtccg
    44641 ggctaaagcc actggttaaa tttgcccgcc gaatggggat tgaatggcat gtactggtcg
    44701 atggcgatga agcagggaag aaatatgccg ctacggtacg cagcctgttg aataacgatc
    44761 gggaagccga acgagaacat ttaacggcgt taccggcgct ggatatggaa cattttatgt
    44821 atcgccaggg attttccgat gtgttccacc gcgtggcgca aatcccggaa aatgtaccga
    44881 tgaatctgcg caaaattatc tcgaaagcga tccatcgctc ttccaaaccc gatcttgcca
    44941 ttgaagtggc aatggaggcc ggacgtcgtg gtgtggactc cgtaccgacg ctgctgaaaa
    45001 aaatgttctc acgcgtgctg tggctggcgc gcggtcgcgc ggattaaccg cgaaacatcg
    45061 tggccatttg tggctgaata gcgtcgagca tctcatagcg ccgacggtat tcagcccgtt
    45121 ttttactggc gatttcggca atctcttttc gtgctatctg tgctggaagg cggtaatggc
    45181 gttcagcatc acatacgccg ccaaccgatt cccagaaagc gttgtaatcg gcatggatct
    45241 tgccttcttt atcacgataa cgcaggctgc ggtaaatatg cgtttcattg ctgacggcaa
    45301 taatctgctc tacctgcaaa cgttgggcaa acagacaggc cgcttccatc acgaggcgtt
    45361 tgggaaatag cccgtggcag gctttcgtcg cattctggat ttcctgatgt ggaatttccc
    45421 attttgcgcc ttgcagtccg ccaataaaca tcgttctttt cccctgatat tcacacaggg
    45481 taaacgtgat ctctgccaga ggaatacctt cgctgttgcg aaacaggatt gtgctgtcac
    45541 cttctttatc cattgagatc atcatggtca gctcaagcgt gaactgctcg ccgtttttgc
    45601 cttccagctt cgccagttgc agcccggggg tattcaaata taagctgaat tcttccgccg
    45661 acatacatcc gcggagtaac gcataatggt aacgtaacgc ctccagcaat tgcttacggc
    45721 taagattcgc cgcaaggtaa gggcgatgca gacgcacagg cagtcgcggt tggcgcgtta
    45781 acaacacatt gagattaggc cagtgggaaa gttcgttcat ccactcaacg cttaaacgcg
    45841 gcataatcaa cgagcgcagc aaaaatttct ggcgaaaact acggcgatgc cagaatttac
    45901 ccggccgaca ctgtccacgt gccagactaa gaaaaagtga caggctgctg agagattcag
    45961 atggcgtaaa ggtccgttca gttagctgcg acatattcat gaaatcaatg gttatacatg
    46021 acgtcgattt caccattgcg tatcttaacc aaacatcaat agtgtgatta ctaacgtaaa
    46081 ttttagggtt ttgttgatat ttcgttgaag ttaatgaccc ggattggcat atggagtatt
    46141 cagaatattt atgaaaaagc ggaaaaccgt gaagaagcgt tacgttattg cgctggtgat
    46201 agtcatcgcc ggactgatta cgttatggag aattcttaac gcacccgtgc cgacttatca
    46261 gacactgatt gtgcgccccg gtgatttaca gcaaagcgtg ctggcgaccg gaaagctgga
    46321 cgcgctgcgt aaggttgacg tgggcgcgca ggtcagcggt cagttgaaaa ctctgtcggt
    46381 ggcgattggc gataaagtaa aaaaagacca gcttttaggg gttattgatc ctgaacaggc
    46441 tgaaaaccag attaaggagg tcgaagcaac gctgatggag ctacgtgcgc agcggcagca
    46501 ggcggaagcg gagctgaaac tggcgcgggt gacgtattcc cgtcagcaac gtctggcaca
    46561 aacgcaggcg gtttcacagc aggatctcga caccgccgcg acggagatgg ctgtgaaaca
    46621 ggcgcaaatt ggcaccattg acgcgcaaat caagcgcaat caggcttctc tcgatacggc
    46681 taaaaccaat ctcgattaca ctcgcatcgt tgccccgatg gccggggaag tcacgcaaat
    46741 caccactctg caaggccaga cggtgattgc cgcacaacaa gcaccgaaca ttctgacgct
    46801 ggcagatatg agcaccatgc tggtaaaagc gcaggtttct gaagcggatg taatccacct
    46861 gaagccgggg caaaaagcct ggtttacggt gcttggcgat ccactgacgc gctacgaggg
    46921 gcaaatcaag gatgtactac cgacgccgga aaaggttaac gacgctattt tctattacgc
    46981 ccgttttgaa gtccccaacc ccaatggttt gctgcggctg gatatgactg cgcaagtgca
    47041 tattcagctc accgatgtga aaaatgtgct gacgatccct ctgtcggcgt taggcgatcc
    47101 ggttggcgat aatcgttata aagtcaaatt gttgcgtaat ggtgaaacac gcgagcgtga
    47161 agtgacgatt ggcgcacgta acgataccga tgttgagatt gtcaaagggc ttgaagcggg
    47221 cgatgaagtg gtgattggtg aggccaaacc aggagctgca caatgacgcc tttgctcgaa
    47281 ttaaaggata ttcgtcgcag ctatcctgcc ggtgatgagc aggttgaggt gctgaagggc
    47341 atcaccctcg atatttatgc cggtgagatg gtagcgattg ttggcgcttc aggttccggt
    47401 aaatcgaccc tgatgaatat tctcggctgt ctggataagg ccaccagcgg cacctatcgc
    47461 gtcgccggtc aggatgttgc cacactggac gccgatgcgc tggcgcaact gcgccgcgag
    47521 catttcggct ttattttcca gcgttaccat ttactttcgc atttaaccgc cgagcagaac
    47581 gttgaagtac ccgccgtcta tgccggtctt gagcggaaac agcggctgct tcgcgcccag
    47641 gggttactgc aacgactggg gctggaagac cgtacagagt attatccggc acagctttcg
    47701 ggtggtcagc aacagcgcgt cagcatcgcg cgggcattga tgaacggcgg tcaggtaatt
    47761 cttgccgatg aaccaaccgg cgcactggac agccattctg gcgaagaggt gatggcgatc
    47821 ctgcatcagc tgcgcgatcg cgggcatacg gtgattatcg tcacccacga tccgcaggtc
    47881 gctgctcagg ccgagcgggt gatcgaaatt cgcgacggcg aaattgtgcg caatcctccc
    47941 gccattgaaa aagtgaatgt tgctggcggg acggagcctg ttgtcaacac ggtgtctggc
    48001 tggcggcagt ttgtcagcgg ttttaacgag gcgctgacga tggcatggcg ggcgctggca
    48061 gcgaataaaa tgcgtacttt actgaccatg ctggggatta ttatcggtat tgcgtcggtg
    48121 gtttccattg tcgtggtggg tgacgccgcc aaacaaatgg tgctggcgga tattcgttct
    48181 attggtacga atactattga tgtctatccc gggaaagatt ttggcgatga cgatccgcaa
    48241 tatcagcagg cgctgaagta cgacgactta atcgccatcc aaaaacaacc gtgggtcgcc
    48301 tcagccacac ctgccgtctc gcaaaacctg cgcctgcgtt ataacaatgt tgatgttgct
    48361 gccagtgcca atggcgtgag cggcgattat tttaatgtct atggcatgac cttcagtgaa
    48421 ggaaacacct ttaatcagga gcagctgaac ggtcgtgcgc aggtcgtggt tctcgacagt
    48481 aatactcgcc gccagctttt cccccataaa gcagatgtgg ttggcgaggt gattctggtc
    48541 ggcaatatgc ccgccagagt cattggtgtg gcggaagaaa aacagtcgat gtttggtagc
    48601 agtaaagtgc tgcgtgtctg gctaccttac agcacgatgt ccgggcgagt tatgggccag
    48661 tcgtggctga actccattac tgtcagggta aaagaaggat ttgacagcgc cgagacggaa
    48721 cagcaactca cgcgtttact ttcactgcgc cacggaaaga aggatttctt tacctggaac
    48781 atggacggcg tcttgaaaac tgttgaaaag accacacgta ctttacaact gtttctgacg
    48841 ctggtggcgg tgatttcgct ggtggtgggc ggtattggtg taatgaatat tatgctggtg
    48901 tcagtgatcg agcggacgcg ggaaattggc attcgcatgg ctgtaggtgc gcgagcaagc
    48961 gatgttttgc aacagttcct gatcgaagcc gtactggttt gcctggtcgg tggcgcgttg
    49021 ggaataactc tgtcactgtt aattgctttc accttgcagc ttttcttacc cggctgggag
    49081 attggttttt caccgttggc actgctgctg gcgtttctct gctcgacggc caccgggatt
    49141 ttatttggat ggttacccgc acgaaatgcg gcacgactgg atccagtaga tgctctggca
    49201 cgagagtaat ttttgagata aaaatgccag ccgatcgggc tggcattttg cctttaggat
    49261 gtacacaatg agacagaaga gctatgcgac tgccgcttct acttcgacgg gcacaataac
    49321 actggcgtga ttgccttttg gcccctggtg gacatcaaac tgaacggatt gtccagcttt
    49381 tagcgttctg taaccatcca tctgaatggt ggaataatga gcgaaaatat cttcgccgcc
    49441 gccttcaggg cagatgaaac caaacccttt ggcattgttg aaccacttaa cagtaccctt
    49501 ttccatgctt cgacatcctt cgcaaatctt atacaagtaa gatggaataa accggggtca
    49561 gagagggggc tgttcaaaac ctcgccaact ctagaaatac aatttagaga attagggcga
    49621 gccgtcaagc gtttgacagg ggccaggggg caggtatgaa tcaaaaattt gaagcagtta
    49681 acgctattga caggaatgtg acagatgtcg ctgatgccaa cgatagatga tagttatcta
    49741 tcatgtggag tagattggtc aggcaaataa gctcttgtca gcggcagggc gttctgccga
    49801 taaccgtaac cgaagatgat aactgacaat gggtaaaacg aacgactggc tggactttga
    49861 tcaactggcg gaagaaaaag ttcgcgacgc gctaaaaccg ccatctatgt ataaagtgat
    49921 attagtcaat gatgattaca ctccgatgga gtttgttatt gacgtgttac aaaaattctt
    49981 ttcttatgat gtagaacgtg caacgcaatt gatgctcgct gttcactacc aggggaaggc
    50041 catttgcgga gtctttaccg ccgaggttgc agaaaccaaa gtggcgatgg tgaacaagta
    50101 cgcgagggag aatgagcatc cattgctgtg tacgctagaa aaagcctgaa tgcaggcata
    50161 aaaattgggg gaggtgccta tgctcaatca agaactggaa ctcagtttaa atatggcttt
    50221 cgccagagcg cgcgagcacc gtcatgagtt tatgaccgtc gagcacttgt tactggcgct
    50281 gctcagtaac ccatctgccc gggaggcgct ggaagcgtgt tctgtggatt tggttgcgct
    50341 ccgtcaggaa ctggaagcct ttattgaaca aaccacaccc gttctgcctg ccagtgaaga
    50401 ggagcgcgac acacagccga cgctgagttt tcagcgtgta ctgcaacgtg cggtcttcca
    50461 tgtccaatcc tccggtcgca atgaggtaac cggtgcaaac gttctggtcg ctatctttag
    50521 cgaacaggag tcgcaggcgg catatctgtt gcgtaaacat gaagtcagcc gtctcgatgt
    50581 ggtgaacttt atctctcatg gcacgcgtaa agacgagccg acacagtctt ctgatcctgg
    50641 cagccagcca aacagcgaag aacaagctgg tggggaggaa cgtatggaga atttcacgac
    50701 gaacctgaat cagcttgcgc gcgtgggcgg aatcgaccca ctgattggtc gtgagaagga
    50761 gctggagcgt gctattcagg ttctctgccg tcgccgtaaa aacaacccgc tgctggtggg
    50821 ggaatctggt gtcggtaaaa ccgcgattgc ggaaggtctt gcctggcgaa ttgttcaggg
    50881 cgatgtgccg gaagtgatgg ctgactgtac gatttactct ctcgatatcg gttctctgtt
    50941 agcgggcact aaatatcgcg gcgactttga aaaacgtttt aaagcgttgc tcaagcagct
    51001 ggagcaggac actaacagca tcctgtttat tgatgagatc cacaccatta tcggtgcggg
    51061 ggcagcgtct ggtggccagg tcgatgcggc taacctgatc aaaccgttgc tctccagcgg
    51121 taaaattcgc gtaattggtt cgacaaccta tcaggagttc agcaacattt tcgagaaaga
    51181 ccgtgctctg gcgcgtcgct tccagaaaat tgatattact gaaccgtcga tcgaagaaac
    51241 tgttcaaatc atcaatggcc tgaaaccgaa gtatgaagcg caccacgacg tgcgttatac
    51301 cgcaaaagcg gtgcgtgcag cggtagagct ggcggtgaaa tacattaacg atcgtcatct
    51361 gccggataaa gccattgacg ttatcgacga agcgggcgct cgcgcacgcc tgatgccggt
    51421 aagcaaacgc aagaaaaccg ttaatgtggc ggatattgag tccgtggtgg cccgtattgc
    51481 gcgcattcca gagaagagtg tttctcagag tgaccgcgat accctgaaaa acctcggcga
    51541 tcgcctgaaa atgctggtct tcggtcagga taaagccatt gaggcgctga ctgaagccat
    51601 taagatggcg cgtgcaggtt taggtcacga acataaaccg gttggttcgt tcctgtttgc
    51661 cggccctacc ggggtcggga aaacagaggt gacggtacag ctttcgaaag cgttgggcat
    51721 tgagctgctg cgctttgata tgtccgagta tatggaacgc cataccgtca gccgtctgat
    51781 tggtgcgcct ccgggatacg ttggttttga tcagggaggt ttgctgactg atgcggtcat
    51841 caagcatcca catgcggtgc tgttgctgga cgaaatcgag aaagcgcatc cggacgtgtt
    51901 caatattctg ttgcaggtga tggacaacgg tacgctgacc gataacaacg gacgcaaagc
    51961 ggacttccgt aacgtggtgc tggtgatgac caccaacgcc ggggtacgtg aaactgagcg
    52021 taaatccatt ggtcttatcc accaggataa cagcaccgat gcgatggagg agatcaagaa
    52081 gatctttaca ccggaattcc gtaaccgtct cgacaacatt atctggtttg atcatctgtc
    52141 aaccgacgtg atccatcagg tggtggataa attcatcgtc gagttgcagg ttcagctgga
    52201 tcagaaaggt gtttctctgg aagtgagcca ggaagcgcgt aactggctgg ccgagaaagg
    52261 ttacgaccgg gcaatgggcg cacgtccgat ggcgcgtgtc atccaggaca acctgaaaaa
    52321 accgctcgcc aacgaactgc tgtttggttc gctggtggac ggcggtcagg tcaccgtcgc
    52381 gctggataaa gagaaaaatg agctgactta cggattccag agtgcacaaa agcacaaggc
    52441 ggaagcagcg cattaatctg attgttaggt aggttggtca agtccgtaat ctcgaaagag
    52501 gttacggact ttttgtttat ggggtggagg aggttcagac ccttttttta atgatgatgg
    52561 taagttgttg ataattagtg ctgcgggaag gtaaggataa aaaagggtgc tgcaggagaa
    52621 tgggatggtt ttgctttatt aacaacgggc taaacgtgta gtatttgagt tcactgccat
    52681 acaggcagct tagaaatcga cggggtgcgg taaaaccttt gcgaacgcgt tcactgccgt
    52741 acagacagat aaaatgcgaa aaaaaagctc gcactttcgt acgagctctt ctttaaatat
    52801 ggcggtgagg gggggattcg aacccccgat acgttgccgt atacacactt tccaggcgtg
    52861 ctccttcagc cactcggaca cctcaccaaa ttgttttgtc gcctgacctc atgggtggca
    52921 acggggcgct actataggga gttggagtaa aacggtcaag aagaatttta atgataatta
    52981 ttgtttgctc atactgtaaa caagttgtgc agtatatcta catcgagaca agttacggac
    53041 ttatacttcc aaagtacttc atacatatca caaaataaaa aggccggtta aaccgacctt
    53101 ttactcgttc tttctcttcg cccatcaggc ggtaaaacaa tcagcgacta cggaagacaa
    53161 tgcggccttt gctcaggtcg tacggggtca gttcaacagt cactttgtcg cccgtcagga
    53221 tgcggatgta gtttttgcgc attttaccgg agatgtgtgc agtaaccacg tgaccgtttt
    53281 ctaactctac gcggaacatg gtattaggca acgtttcaag aacggtacct tgcatttcaa
    53341 tattgtcttc tttggccatc taatcctctg gggtatcact accgtaattt gaaccggcaa
    53401 gataatgccg aagttctgta aataagtaaa gatttgcgcg ctaaatcgca acaaacaggt
    53461 tcggcacatt actccgaaaa cacacggcta agccgcacca aaagcgcaac gtataaggga
    53521 gcggtgagat aaacgatggg cgttacctga cgcgaaaaat tccttatcgg cagcggggta
    53581 atgagcgtaa ccaactctgc gaccgcaatt ataacactct ggggagaaat gtgccgaaaa
    53641 cattcattct tgtggtgaaa acaagcatcg tggtacccag aaattattcg gcaatcgtcc
    53701 gaggcgcatt tgattgagat aattaaggta atcccggcgg ggaatttcgc aggcaccaag
    53761 cgatgctgtg tgatcgttaa ggacctggca gtcgataagc ttaccgccat gaccgataaa
    53821 ttcctcacag aataccagaa gcgccgtttt agacgcattt tccatccggc tgaacatgga
    53881 ctcgctacaa aatagcgttc cctgggccac gccgtacata ccgccgacaa gctcatcttc
    53941 acgccagact tcaatggagt gggcatggcc gagttcgtga aggcgatggt aggcttcgac
    54001 cacgccacgc gtgatccagg ttccttcttc gcgatcgctg gcacagcctt caatgacctg
    54061 accaaaagcg taattcatcg tgacacgata gggcgagcgt ttatgaaatc gcttcatact
    54121 acggctgata tgcagtgatt ctggccatag caccgcgcgg ggatcgggcg accaccagag
    54181 gatggggtcg cctggagaaa accacggaaa aataccacgc tggtaagcca ttaacaggcg
    54241 cgcagggcta agatcgcccc caagtgccag caggccgtta ggctcacgta atgcgccttc
    54301 cggggaaggg aaggctattg aatggcgaga aagctgaacc aggcgcatga ccgcaaaact
    54361 ccacgcaagt cggatcgttc aataatagct tacaaaccct gcttgaactg gtaataacgc
    54421 ccctgtctgg caagcagctc tgcgtgagta ccttgctcaa taatttgccc gttgtccatc
    54481 actattattt gttggaaacg agagagtccg cgaagtcgat gggtgaccat taacaccgtt
    54541 ttctcacgca tcatttctgc aagcaattca aggatctggc tttcggttgt ggcatctaag
    54601 ccttcggtag gttcatccag caacaccagt ggcgcatcat gtaacagcgc acgggcgata
    54661 gccagacggc gcagttcacc accggagagc tggcgtccgc cttcacctaa ccaactgttg
    54721 agacctgcat cctcgagcag cttctccagg ccaacgcgac gcaagctctc cgccagagcc
    54781 tcatcactac tgccaggcga ggcgagtaac agattatcac gcagcgtggc gctaaacaga
    54841 tgcactcgct gaggaacaac gctgatggtc tgtcgtagag ccgcttcatt caggctggct
    54901 atggggctat cgttaagcaa aatctcgccc tgttgcgggt cccaagcgcg ggtcagcagt
    54961 tgtaacagtg ttgatttgcc gcatccggtt cgcccgagaa tcgcaatatg ttccccggcg
    55021 tttacctgaa gagaaatccc tttaagtgcc tgttgggatt gctccggata agtgaactga
    55081 acatcccgta atgtcagcga aacgcgatcg gcaacacgag tttgggtatc agggaaggtg
    55141 acttccggtt tttgatccgt taaatcagtg atccgaacgg cagaggcaat gacttgcccc
    55201 agatgctgaa atgcacccgt tactggtgcc agtgcttcaa acgcggctaa cgcgcagaag
    55261 acaaacaggg caattaacgc gccgggttga gcattgccgc caacgccgcc agacgccatc
    55321 cacagcatca ggatcaccgc taacgcgcca atgagtagca ttatcgcttg cgacaatgcg
    55381 gtcagttcag attgacggcg ttgcgcttcc agccattgaa tttctgtatt ctctagttgc
    55441 gtgcgataac gatcgctggc accaaaaatg gtcagctcag cttgcccttg cagccaggcc
    55501 gtcagttgtt ggcgatactg tccgcgaaga tgagtcagat tttgcccggt gctttttccc
    55561 gcacgataaa acagcggtgg catcaggaaa agcgtcagta acataatgcc gcccagcgta
    55621 aaggcgaggg tgaaatcaag gaaacttaac ccgattgtca ccaccataat caccacaaaa
    55681 gcgcccacca gcggcgagat aacgcgcaga taaagatgat cgagcgtatc aacatccgcc
    55741 accacgcgat tgagcaattc gccctgacga tagcgcgcca gtccggcagg ggagaggggc
    55801 agcaatttgc tgaaggtgta aatgcgcaga tgctgcaaca cgcggaaagt cgcgtcgtga
    55861 cttaccagac gttcaaaata acgcccggca gtacgggtga ttgctgcgcc acgcacgccc
    55921 gcagcgggta gcatatagtt gaagctgtac agtccggcaa cccccgcaac cgctgaggcc
    55981 gagaggaacc agccggaaag tgtcaacaga ccgatactgg cgagcagcgt gacaattgcc
    56041 agcacgatac caagacttaa catccattta tgacgtttat acagtgccag atagggtagc
    56101 aaagcgcgca tttaaatctc ctcctgacga tgggccagta atgtggcgaa tgggccacca
    56161 gccacactta attccgcgta acgtccttgc tcaataatcc ggccatcctg cataacccaa
    56221 atgacatccc agtcagcaag atcttctaac tggtgggtga ccattaacgt tgtctggcgc
    56281 agagaggcgg cattcagcgc ctccattacg cgctgttcac tgtgagcatc aaggctggca
    56341 gcgggttcat ccaacagtaa tagcgaacag ggatttagta acgcacgggc caccgccacg
    56401 cgctgcgcct gccccacgga aaggcgggca gcctggtcgc caacaggcgt atcaacgcct
    56461 tgtggcagga gcggtagaaa ctcgctgacc caggcgttat ccagcgctgc ttgtaattct
    56521 tgttcgctgg catcaggtcg cgccagtagt acgttatccc gcaatgttgc tgccggtaat
    56581 tgtgggtttt gcccaaccca ggagagatgt ttacgccatg attctggtga taaatcgcgt
    56641 aattctatcc cgttgattcg taatgatccc tgatatgaaa gaaaaccaga aagcgcgttc
    56701 agcagtgagc ttttacctga accgctgcga ccaaccaaca ctgcacgttg gcctgctggc
    56761 aaagtaaagt tcagcggtcc ggccagcgtt ttaccttccg gcgacgtgat aaacagatcc
    56821 tcggcctcaa tggtcaccgg atcggtcgat gctaattccg cctcaccgcg ctgcggatgg
    56881 gcgagcgggg tttccataaa cgttttcaga ctgtcagctg caccaacagc ctgggcttta
    56941 gcatgataaa acgtaccgag atcgcgcaat ggctggaaaa actctggcgc aaggatcagg
    57001 gccagaaaac ccgcagccag cgtcacaccg gtatcgtagt gaccaaaatc cagctcgccg
    57061 agataggaaa aaccaaagta gaccgccacc agagcaattg acagcgaggt aaaaaattcg
    57121 agaatgccgg aggataaaaa cgccagccgt agcacttcca ttgtccgttg gcggaaatct
    57181 tccgaagcag aacgaatact ttcaatttca gcttcaccac gaccaaaaat acgcaatgtt
    57241 tccatgccgc gcaggcgatc gaggaaatgc ccacttaagc gagcaagagc gagaaagtta
    57301 cgccggttag catcggcagc ccccatccca accagcgcca taaacaacgg aattaacggt
    57361 gctgtgccca gcagaatgag cgccgcagcc cagttagagg ggaagatcgc caccacaatc
    57421 agcaacggca ccgacactgc cagcgccatt tgcggcaggt agcgtgcata gtaatcatgc
    57481 atatcgtcaa tttgctcgag taccaacgtc gcccagctcc ccgcaggttt accctgaatc
    57541 cacgctggcc ctgcttgttg cagacggtcg agaacctgac ggcggatggc aaagcggata
    57601 tgctgcccgg cgtgataacc cacccgttcg cgtaaccaga ccacccatgc gcgcagtaca
    57661 aaggtcagaa ccagtaacgt aaagggaagc agcagggctt cacggggaat attctccata
    57721 atcatatgtt gcagaattcg cgccatgaac caggcctggg caataatcaa tatgccgctt
    57781 acaaagccca gcagacgaga aatattcagc caacgttggg agatgacgct ttgctgtttt
    57841 aaccagcggg ttaactcttt ttgacgggat ttattcattg cacgcttagc aggtgagtta
    57901 tcagaattat ttgcagagca atgttacaac ggggaaaaaa taaaggcgac ccatagtcgc
    57961 atggtgtcgc cttctttact tttgttactg atttgtaaaa ttattttgcg tcagctaaac
    58021 catcgaggta gcgttccgca tcaagtgctg ccatgcagcc tgtaccggcc gaagtaatgg
    58081 cctgacgata aatatgatcc atcacgtcac ccgcggcaaa gacgccaggg atgctggtct
    58141 gggtggcatt accatgaata cccgactgca ctttgatgta gccgttttcc agttccagct
    58201 gcccttcgaa aatggcagta ttcgggctgt gaccgatagc aacaaacaga ccagcaacgt
    58261 cgagtgactc gatgttatcg ctgttttgcg tatcgcgcag acgaacgcca gtgacaccca
    58321 tttgatcgcc ggtcacttct tccagcgtac ggttggtgtg cagaatgatg ttgccgttct
    58381 ccactttatc catcagacgc ttaataagga ttttttccgc gcggaaaccg tcacggcggt
    58441 gaatcagatg cacttccgaa gcgatgttag acagatacag cgcctcttca accgcggtat
    58501 tgccgccgcc gatgaccgca actttctggt tgcgatagaa gaaaccgtcg caggttgcac
    58561 aagcagaaac cccacggcct ttaaaggctt cttcagaggg caggccgaga tagcgtgcag
    58621 aagctccggt ggcaataatc agcgcgtcgc aagtgtattc gccgttatcg ccattcagac
    58681 ggaacggacg gttttgcaga tccaccttgt tgatatgatc aaaaatgatc tcagtttcaa
    58741 acttggtggc atgttcgtgc atgcgctcca ttaataacgg accggtcaga tcgtttggat
    58801 cgccaggcca gttttccact tccgtggtgg tggtcagttg gccgcctttt tccatgccgg
    58861 taatcagcac aggttgcagg ttggcgcgcg ccgcgtagac agcagcggtg tatcccgccg
    58921 ggcctgaacc caggataagc agtttactgt gtttggtcgt gcccatgaga tccccatagt
    58981 tgttggcaga caatgggcag gattgtaggg aatttacaga cgtaaaaaaa gagtatgacg
    59041 attttgttaa caatttgtgc aatcggcagc atcgataagc aggtcaaatt ctcccgtcat
    59101 tatcacctct gctacttaaa tttcccgctt tataagccga ttaaatgatg aataaacgcc
    59161 cctgttaatg aatatctggc atgttgtact aaaaatcgat gttttgcttt gacaatcccc
    59221 tggtgttttg cgaaaacatt cgaggaagaa aaaaaacagt attcttatat gcgcataacc
    59281 atgcatgtaa ataccatgtt taccgtgcta gtgaaatcta cgtatggcgt ggacagacgc
    59341 cattcgtgat gtcgatagct gccacaaggc aacggtcttc tcaccgtaga cccaggcatt
    59401 gcgcgccgtg aatcttcatg atttcggtct atcgtgacgg gtagcgactc tgaacagtga
    59461 tgtttcaggg tcagacagga gtagggaagg aatacagaga gacaataata atggtagata
    59521 gcaagaagcg ccctggcaaa gatctcgacc gtatcgatcg taacattctt aatgagttgc
    59581 aaaaggatgg gcgtatttct aacgtcgagc tttctaaacg tgtgggactt tccccaacgc
    59641 cgtgccttga gcgtgtgcgt cggctggaaa gacaagggtt tattcagggc tatacggcgc
    59701 tgcttaaccc ccattatctg gatgcatcac ttctggtatt cgttgagatt actctgaatc
    59761 gtggcgcacc ggatgtgttt gaacaattca ataccgctgt acaaaaactt gaagaaattc
    59821 aggagtgtca tttagtatct ggtgatttcg actacctgtt gaaaacacgc gtgccggata
    59881 tgtcagctta ccgtaagttg ctgggggaaa ccctgctgcg tctgcctggc gtcaatgaca
    59941 cacggacata cgttgttatg gaagaagtca agcagagtaa tcgtctggtt attaagacgc
    60001 gctaacacgg aacaggtgca aaatcggcgt attttgatta cactcctgtt aatccataca
    60061 gcaacagtac tggggtaacc tggtactgtt gtccgtttta gcatcgggca ggaaaagcct
    60121 gtaacctgga gagcctttct tgagccagga atacactgaa gacaaagaag tcacattgac
    60181 aaagttaagt agcggccgtc gccttctgga agcgttgctg atccttattg tcctgtttgc
    60241 cgtctggttg atggctgcct tactaagctt taacccttcg gaccccagct ggtcgcaaac
    60301 ggcctggcat gaacctatcc ataatttagg tgggatgccc ggtgcgtggc tggcagatac
    60361 gctgttcttt atttttggcg tgatggctta caccattccc gtcattattg tcggcggttg
    60421 ttggtttgcc tggcgtcatc agtccagtga cgaatacatt gattattttg ccgtttcgct
    60481 acgcatcatt ggcgttttgg cgctcatcct tacctcctgt ggtctggcgg caatcaacgc
    60541 tgacgatatc tggtattttg cctccggtgg cgtcattggc agcttactaa gcactacgct
    60601 acaaccactg ctacacagta gcgggggaac tattgcgctg ctctgcgttt gggctgcggg
    60661 cctgacgctg ttcaccggtt ggtcatgggt gaccattgct gaaaaactcg gcggctggat
    60721 tttaaacatt ctcaccttcg ccagtaatcg tacccgtcgc gatgatacct gggtcgatga
    60781 agatgaatat gaagatgacg aagagtatga agatgaaaac cacggcaaac agcatgaatc
    60841 gcgccgtgcc cgtattcttc gcggcgcgct agcgcgtcgt aaacggttgg cggaaaaatt
    60901 cattaatccg atggggcggc aaacagacgc tgcgttgttc tccggtaagc ggatggatga
    60961 tgacgaagag attatctaca ctgcacgcgg tgtggctgcc gacccggacg acgtcctatt
    61021 ttcgggcaat cgtgcaacgc agccagaata tgacgaatac gatccattat taaacggtgc
    61081 gccaattacc gaacctgtcg ctgtagcagc tgctgctacc acggcgacac aaagctgggc
    61141 tgcgccggtt gaacctgtga ctcagacgcc gcctgttgcc tctgttgatg ttccaccttc
    61201 gcaacctaca gtagcctggc agcctgtacc gggtccacaa acgggagagc cggttattgc
    61261 tcctgcaccg gaaggttacc cacagcagtc acaatatgcg cagcctgcag tgcaatataa
    61321 tgagccgctg caacaaccag tacagccgca gcagccgtat tatgcacctg cagctgaaca
    61381 acctgcgcaa caaccttact acgctcctgc ggcggaacaa cctgttcagc aaccgtatta
    61441 cgcccctgcg ccagaacaac cggtggcagg taacgcctgg caagccgaag agcagcaatc
    61501 cacttttgct ccacagtcta cataccagac tgagcaaact tatcagcaac cagccgctca
    61561 ggagccgttg taccaacagc cgcaatccgt tgaacagcag cctgttgtgg agcctgaacc
    61621 cgttgtagaa gagacaaaac ccgcgcgtcc gccgctttac tattttgaag aagtggaaga
    61681 gaagcgagcc cgtgaacgtg aacaacttgc ggcctggtat caaccgattc cagaaccggt
    61741 taaagaacca gaaccgatca aatcttcgtt gaaagcgcct tctgttgcag cagtacctcc
    61801 agtagaagcc gctgccgctg tttctccgct ggcatctggc gtgaaaaaag cgacactggc
    61861 gacgggggct gccgcaaccg ttgccgcgcc agtcttcagt ctggcaaata gcggtggacc
    61921 gcgtccgcaa gtcaaagagg ggattggccc gcagttgcca cgaccgaaac gtatccgcgt
    61981 gccaactcgt cgtgaactgg cgtcttacgg tattaagctg ccctcacagc gtgcggcgga
    62041 agagaaagcc cgtgaagccc agcgcaatca gtatgattct ggcgatcagt ataacgatga
    62101 tgaaatcgat gcgatgcagc aggatgaact ggcacgtcag ttcgcccaga cacagcagca
    62161 acgctatggc gaacagtatc aacatgatgt gcccgtaaac gcagaagatg cagatgctgc
    62221 ggcagaggct gaactggctc gtcagtttgc gcaaactcaa caacaacgtt attccggcga
    62281 acaaccggct ggggcgaatc cgttctcgct ggatgatttt gaattttcgc caatgaaagc
    62341 gttgctggat gatggtccac acgaaccgtt gtttacgcca attgttgaac ctgtacagca
    62401 gccgcaacaa ccggttgcac cgcagcagca gtatcagcag ccgcaacaac cagttccgcc
    62461 acagcagcaa tatcagcagc cgcaacagcc ggttgcgccg cagccgcagt atcagcagcc
    62521 acaacagcag gttgcgccgc agccgcagta tcagcagcca caacaaccgg ttgcgccaca
    62581 gccgcaatat cagcagccgc aacaaccagt tgcgccgcag ccgcagtatc aacagccgca
    62641 acaaccggtt gcaccgcagc agcaggatac cctgcttcat ccgctgttga tgcgtaatgg
    62701 cgacagccgt ccgttgcata aaccgacgac gccgctgcct tctctggatt tgctgacacc
    62761 gccgccgagc gaagtggagc cggtagatac ctttgcgctt gaacaaatgg ctcgcctggt
    62821 ggaagcgcgt ctggctgatt tccgtattaa agccgatgtc gtcaattact ctccggggcc
    62881 ggttatcact cgctttgaac ttaacctggc tcctggcgta aaagcggcgc gcatttctaa
    62941 cttgtcacgg gaccttgccc gttcactttc gacggtggcg gtgcgtgtcg ttgaagttat
    63001 tcctggcaaa ccctatgtag gtctggagtt accaaataaa aaacgacaaa ccgtttatct
    63061 gcgcgaagtt ttggataacg ccaaattccg cgataatccg tcgccattaa ccgtggtgct
    63121 gggtaaagat atcgccggtg agccggtggt tgccgatctg gcgaaaatgc cgcacttgtt
    63181 ggttgcgggg actaccggtt ccggtaaatc tgtcggtgtg aacgcgatga tcctgagcat
    63241 gctttataaa gcacagccag aagatgtgcg tttcatcatg atcgacccga aaatgctgga
    63301 gctttcggtt tatgaaggca ttccgcatct gttaacagaa gtcgttactg atatgaaaga
    63361 tgccgccaac gcgctgcgct ggtgtgttaa cgagatggag cgtcggtata aactgatgtc
    63421 tgcgctgggt gtgcgtaatc tggcgggtta taacgaaaaa attgctgaag ccgatcgcat
    63481 gatgcgtccg attccagacc cgtactggaa gccgggtgac agtatggatg cccagcatcc
    63541 ggtgctgaaa aaagaaccat acattgtggt gttggttgac gaatttgccg acctgatgat
    63601 gacggtaggt aaaaaagtgg aagagctgat agcacgtctg gcgcaaaaag cccgtgccgc
    63661 gggtatccac ctcgtactgg caactcagcg tccatcggtt gatgttatta ctggtctgat
    63721 taaagcgaat attccgaccc gtatcgcctt taccgtatcc agtaagattg actcacgtac
    63781 cattcttgat caggctggcg cggaatcact gctggggatg ggggatatgc tctactctgg
    63841 gccgaactcc acgttgccgg tacgtgtcca tggtgctttt gttcgcgatc aggaagttca
    63901 tgccgtggtg caggactgga aagcgcgtgg tcgcccacag tatgttgatg gcatcacttc
    63961 cgacagtgaa agcgaaggtg gcgcgggcgg tttcgatggc gctgaagaac tggatccgtt
    64021 gttcgatcag gcggtgcagt ttgtcactga aaaacgcaaa gcgtcaattt ctggcgtaca
    64081 gcgtcagttc cgcattggtt ataaccgtgc agcgcgtatt atcgaacaga tggaagcgca
    64141 ggggattgtc agcgaacagg ggcacaacgg taatcgtgaa gtgctggccc caccgccgtt
    64201 tgactaatta atgcattgcc ggataaggcg cggtagcgtc gcatccggca ctctatcaac
    64261 tgaaaattca gtattttctt ctttcctcaa gctgattatt agcctggaat agagagtaga
    64321 gggaactccc gatcgggagt gacgtaattt gaggaataat gatgaaaaaa attgccatca
    64381 cctgtgcatt actctcaagc ttagtagcaa gcagcgtttg ggctgatgcc gcaagcgatc
    64441 tgaaaagccg cctggataaa gtcagcagct tccacgccag cttcacacaa aaagtgactg
    64501 acggtagcgg cgcggcggtg caggaaggtc agggcgatct gtgggtgaaa cgtccaaact
    64561 tattcaactg gcatatgaca caacctgatg aaagcattct ggtttctgac ggtaaaacac
    64621 tgtggttcta taacccgttc gttgagcaag ctacggcaac ctggctgaaa gatgccaccg
    64681 gtaatacgcc gtttatgctg attgcccgca accagtccag cgactggcag cagtacaata
    64741 tcaaacagaa tggcgatgac tttgtcctga cgccgaaagc cagcaatggc aatctgaagc
    64801 agttcaccat taacgtggga cgtgatggca caatccatca gtttagcgcg gtggagcagg
    64861 acgatcagcg cagcagttat caactgaaat cccagcaaaa tggggctgtg gatgcagcga
    64921 aatttacctt caccccgccg caaggcgtca cggtagatga tcaacgtaag tagaggcacc
    64981 tgagtgagca atctgtcgct cgatttttcg gataatactt ttcaacctct ggccgcgcgt
    65041 atgcggccag aaaatttagc acagtatatc ggccagcaac atttgctggc tgcggggaag
    65101 ccgttgccgc gcgctatcga agccgggcat ttacattcta tgatcctctg ggggccaccg
    65161 ggtaccggca aaacaaccct cgctgaagtg attgcccgct atgcgaacgc tgatgtggaa
    65221 cgtatttctg ccgtcacctc tggcgtgaaa gagattcgcg aggcgatcga gcgcgcccgg
    65281 caaaaccgca atgcaggtcg ccgcactatt ctttttgttg acgaagttca ccgtttcaac
    65341 aaaagccagc aggatgcatt tctgccacat attgaagacg gcaccatcac ttttattggc
    65401 gcaaccactg aaaacccgtc gtttgagctt aattcggcac tgctttcccg tgcccgtgtc
    65461 tatctgttga aatccctgag tacagaggat attgagcaag tactaactca ggcgatggaa
    65521 gacaaaacgc gtggctatgg tggtcaggat attgttctgc cagatgaaac acgacgcgcc
    65581 attgctgaac tggtgaatgg cgacgcgcgc cgggcgttaa atacgctgga aatgatggcg
    65641 gatatggccg aagtcaatga tagcggtaag cgggtcctga agcctgaatt attgaccgaa
    65701 atcgccggtg agcgaagcgc ccgctttgat aacaaaggcg atcgctttta cgatctgatt
    65761 tccgcactgc ataagtcggt acgtggtagc gcacccgatg cggcgctgta ctggtatgcg
    65821 cgaattatta ccgccggtgg cgatccgtta tatgtcgcgc gtcgctgtct ggcgatagcg
    65881 tctgaagatg tgggtaatgc tgatccacga gcgatgcagg tggcaattgc ggcctgggat
    65941 tgctttactc gcgttggccc ggcggaaggt gaacgcgcca ttgctcaggc gattgtttac
    66001 ctggcctgcg cgccaaaaag caacgctgtc tacactgcgt ttaaagccgc gctggcggat
    66061 gctcgcgaac gtccggatta tgacgtgccg gttcatttgc gtaatgcgcc gacgaaatta
    66121 atgaaggaaa tgggctacgg gcaggaatat cgttacgctc atgatgaagc aaacgcttat
    66181 gctgccggtg aggtttactt cccgccggaa atagcacaaa cacgctatta tttcccgaca
    66241 aacaggggcc ttgaaggcaa gattggcgaa aagctcgcct ggctggctga acaggatcaa
    66301 aatagcccca taaaacgcta ccgttaatgt tatcgttgcg gtaatgttgt tactgtatcc
    66361 ctgtggtcgc aggctgtggc cacatctccc atttaattcg ataagcacag gataagcatg
    66421 ctcgatccca atctgctgcg taatgagcca gacgcagtcg ctgaaaaact ggcacgccgg
    66481 ggctttaagc tggatgtaga taagctgggc gctcttgaag agcgtcgtaa agtattgcag
    66541 gtcaaaacgg aaaacctgca agcggagcgt aactcccgat cgaaatccat tggccaggcg
    66601 aaagcgcgcg gggaagatat cgagccttta cgtctggaag tgaacaaact gggcgaagag
    66661 ctggatgcag caaaagccga gctggatgct ttacaggctg aaattcgcga tatcgcgcta
    66721 accatcccta acttgcctgc agatgaagtg ccggtaggta aagacgaaaa tgacaacgtt
    66781 gaagtcagcc gctggggcac cccgcgtgag tttgactttg aagttcgtga ccacgtgacg
    66841 ctgggtgaaa tgcactctgg cctcgacttt gcagccgcag ttaagctgac aggttcgcgc
    66901 tttgtggtga tgaaagggca gattgctcgc atgcaccgcg cactgtcgca gtttatgctg
    66961 gatctgcata ccgaacagca tggctacagt gagaactatg ttccgtacct ggttaaccag
    67021 gacacgctgt acggtacggg tcagctgccg aaatttgctg gcgatctgtt ccatactcgt
    67081 ccgctggaag aagaagcaga caccagtaac tatgcgctga tcccaacggc agaagttccg
    67141 ctgaccaacc tggtacgcgg tgaaatcatt gatgaagatg atctgccaat taagatgacc
    67201 gcccacaccc catgcttccg ttctgaagcc ggttcatatg gtcgtgacac ccgtggtctg
    67261 atccgtatgc accagttcga caaagttgaa atggtgcaga tcgtgcgccc ggaagactca
    67321 atggcggcgc tggaagagat gactggtcat gcagaaaaag tcctgcaact gctgggccta
    67381 ccgtaccgta aaatcatcct ttgtaccggc gacatgggct ttggcgcttg caaaacttac
    67441 gacctggaag tatggatccc ggcacagaac acctaccgcg agatctcttc ctgctccaac
    67501 gtttgggatt tccaggcgcg tcgtatgcag gctcgttgcc gcagcaagtc ggacaagaaa
    67561 acccgtctgg ttcataccct gaacggttct ggtctggctg ttggtcgtac gctggttgca
    67621 gtaatggaaa actatcagca ggctgatggt cgtattgaag taccagaagt tctgcgtccg
    67681 tatatgaacg gactggaata tattggctaa tacccaattt ttctgaatct aaaaagcgcc
    67741 tgcgggcgct ttttttgtct ccctttgata ccgaacaata attactcctc acttacacgt
    67801 aatactactt tcgagtgaaa atctacctat ctctttgatt ttcaaattat tcgatgtata
    67861 caagcctata tagcgagctg ctatagaaat aattacacaa tacggtttgt tactggaatc
    67921 aatcgtgagc aagcttgagt gagccattat gaaaacgaaa atccctgatg cggtattggc
    67981 tgctgaggtg agtcgccgtg gtttggtaaa aacgacagcg atcggcggcc tggcaatggc
    68041 cagcagcgca ttaacattac cttttagtcg gattgcgcac gctgtcgata gcgccattcc
    68101 aacaaaatca gacgaaaagg ttatctggag cgcctgtaca gttaactgtg gtagtcgctg
    68161 cccgctacgt atgcacgtcg tggacggtga aatcaaatat gtcgaaacgg acaataccgg
    68221 cgatgacaat tacgacggcc tgcaccaggt tcgcgcctgt ctgcgtggac gttccatgcg
    68281 tcgccgtgtc tataatccgg accgcctgaa atatccgatg aaacgagtcg gggcgcgcgg
    68341 tgaaggcaaa tttgagcgca ttagctggga agaagcctac gacatcatcg cgaccaatat
    68401 gcagcgcctg atcaaagagt acggcaacga atccatctat ctgaactatg gcaccggtac
    68461 gctgggcggc accatgaccc gctcctggcc cccgggaaat accctggtcg cgcgcctgat
    68521 gaactgctgc ggcggttatc tgaaccatta cggtgactac tcttccgcgc aaattgcgga
    68581 aggtttgaac tatacctacg gcggctgggc agatggtaac agcccgtcgg atatcgaaaa
    68641 cagtaaactg gtagtgctgt ttggtaataa ccctggcgaa acgcgaatga gtggcggtgg
    68701 ggtgacttac tatcttgaac aggcacgcca gaaatctaat gcccgcatga tcatcatcga
    68761 tccgcgctat accgacaccg gtgccgggcg cgaagatgag tggatcccta ttcgtccggg
    68821 aacagatgcc gcactggtta acggtctggc gtacgtcatg atcactgaaa acctggtgga
    68881 tcaggcattc ctcgataaat attgcgttgg ctacgatgag aaaaccctgc cagccagtgc
    68941 gccgaaaaat ggccactata aagcttatat tctgggtgaa gggccagatg gcgtggctaa
    69001 aacaccggaa tgggcctcac aaatcaccgg tgttccggca gacaaaatca tcaaactggc
    69061 tcgtgaaatc ggcagtacca aaccggcgtt tatcagccag ggatggggcc cgcagcgtca
    69121 cgctaacggt gaaatcgcaa cccgtgctat ctcgatgctg gcgattctga ccggtaacgt
    69181 tggtattaac ggaggcaaca gcggcgcgcg tgaaggttca tacagcttac cgtttgtccg
    69241 tatgccgacc ttggaaaacc cgatccagac cagcatttcg atgtttatgt ggaccgatgc
    69301 cattgaacgt ggcccggaaa tgacggcgct gcgtgatggt gtacgcggga aagataagct
    69361 ggatgtgccg atcaaaatga tctggaacta tgccggtaac tgcctgatta accagcattc
    69421 tgaaatcaac cgtacccatg aaatccttca ggatgataag aagtgcgagc tgattgtggt
    69481 tatcgactgc cacatgacct catcggcgaa atatgctgac atcctgctgc ctgactgcac
    69541 cgcttccgaa cagatggact ttgcgctgga tgcatcctgc gggaatatgt cttacgtgat
    69601 tttcaacgat caggtgatta aaccgcgctt tgaatgtaag accatctatg aaatgaccag
    69661 cgaactggca aaacgtcttg gcgttgagca acagtttact gaaggccgta cacaggaaga
    69721 gtggatgcgg catctgtatg cccagtcgcg ggaagcgatt cctgaactgc caacgtttga
    69781 agagttccgc aagcagggga tctttaaaaa gcgcgaccca caagggcatc acgttgctta
    69841 taaagccttc cgtgaagatc cgcaggcaaa cccactgact acgccatcgg gcaaaattga
    69901 gatttattcg caggcgctgg ctgacattgc cgctacctgg gaattgccag aaggcgatgt
    69961 gatcgatcca ctgccgatct acacgccggg ctttgaaagt tatcaggatc cgctgaacaa
    70021 acagtatccg ctgcagctta cgggtttcca ctataaatct cgcgttcact caacttacgg
    70081 caacgttgat gtgctgaaag cggcttgccg tcaggaaatg tggatcaacc cgcttgatgc
    70141 gcaaaaacgc ggtatcaaca acggcgataa agtcaggatc tttaacgatc gtggtgaagt
    70201 tcatattgag gcgaaagtga cgccacgaat gatgccgggt gtggtcgcac tgggtgaagg
    70261 tgcctggtat gacccggatg caaaacgtgt cgataagggc ggttgtatta acgtactgac
    70321 cactcaacgt ccgtctcctc tcgctaaggg gaatccgtca catacaaacc ttgttcaggt
    70381 tgaaaaggtg taaggagtaa ccgatgacaa cccagtatgg attttttatt gattccagcc
    70441 gttgcaccgg ttgcaaaacc tgcgagctgg cctgtaaaga ctacaaagat ttgacgccag
    70501 aagtcagctt ccgccgcatt tatgaatatg ctggcggcga ctggcaggaa gataacggtg
    70561 tctggcacca gaacgtgttt gcctactatc tgtcgatttc atgtaaccac tgcgaagatc
    70621 cggcttgtac taaagtctgc ccgagcggtg cgatgcataa acgcgaagat ggttttgttg
    70681 tggtcgatga agatgtatgc attggctgcc gctactgtca tatggcttgc ccgtatggcg
    70741 caccgcaata taacgaaacg aaaggccata tgaccaaatg cgatggttgt tatgaccgtg
    70801 ttgcggaggg taaaaagccg atctgtgttg aatcttgccc gctgcgggcg ctggatttcg
    70861 gtcctatcga cgagctgcgt aaaaaacatg gcgatctggc ggccgttgcg ccgttgccgc
    70921 gagctcactt taccaaaccg aatattgtga tcaaacccaa tgccaacagc cgcccgaccg
    70981 gggataccac tggctacctg gcaaacccga aggaggtgtg agatgggaag tggatggcat
    71041 gaatggccgc tgatgatctt cacggtcttc gggcaatgtg tagcgggtgg ttttatcgtt
    71101 ctggctttgg cgctgctcaa aggcgacctg cgagcagaag cccagcagcg tgttatcgcc
    71161 tgcatgtttg gcttatgggt gctgatgggc attggcttta tcgcctctat gctccatctt
    71221 ggttcaccga tgcgcgcctt taactcgctc aaccgggtag gggcttcagc actcagtaac
    71281 gaaatcgcca gcggttcgat cttttttgct gtaggcggca tcggctggtt gctggcaatg
    71341 ctgaaaaagc tgtcaccggc attgcgtacg ctatggctgg tggtgacgat ggttcttggc
    71401 gtcgtctttg tctggatgat ggtgcgtgtg tataacagca ttgataccgt tccgacctgg
    71461 tacagcatct ggacgccgat gggcttcttc ctgacgatgt tcatgggcgg cccgttactg
    71521 ggttacctgt tgctgagtct ggctggcgtc gatggctggg cgatgcgtct gctgccagcc
    71581 atttctgtac tggcactggt ggtgagtggt gtgatgtcag tgatgcaggg cacagagctg
    71641 gcaactattc atagttctgt gcagcaggcc gcagcgctgg tgccggacta tggtgcgctg
    71701 atgtcctggc ggatcgtgct tttggccgtt gccctgtgct tgtggattgc accacagcta
    71761 aaaggttatc agcctgcggt tccgctacta tccgtctcat tcattctgct tctggcaggg
    71821 gaattaatcg gtcgcggcgt attctatggt ttgcatatga ccgtggggat ggccgtcgca
    71881 agctaatcag taacaaccgg ggtttcggcc ccggttctct tttatttctg cttcgttaac
    71941 gtgtcataac tggtcatcaa attacgataa tcaggaatat ggttagagaa caacgtcgcc
    72001 agtccttcaa tatcattacg ccagtcacgg tgcagctcgc acgccacgcc gaaccatgtc
    72061 atcaattgcg cacctgcttg cgacatgcga tcccatgccg aatgccgggt aatttcatta
    72121 aaggtccctg acgcgtcagt cacgacaaag acgtcaaacc cttcttcaat ggctgaaagc
    72181 gccgggaatg ccacgcaaac ttcggttacc acaccggcaa taattaactg ttttttacct
    72241 gtcgctttga ctgcttttac aaaatcttcg ttatcccagg cgttaatatt tcccgggcga
    72301 gcaatgtaag gtgcatcggg gaattgtgct ttcagttctg gaactaatgg accgttagga
    72361 ccggtttcaa aactggtggt aagaatagtt ggtaagttga aatacttagc caggtcaccc
    72421 agcgccagca cgttattttt aaacttatcg ggttcgatat cccgtacaag ggaaagtaaa
    72481 ccagcctggt gatcaacaag caaaacggca gcatcatttt tatcaagacg aacatacggt
    72541 ttggtcatcc tcttctcctt tcgagagtca gtggtacgtc tgaaatcggt cagacgcgat
    72601 gcattgctct gaaagcatag acgggaaata tgagtttgct gtgaccatga aatttttcga
    72661 ctgaacgaag cgtatgaaat ttgtgttaga tcaataaaaa caatcagatg agattaatcg
    72721 tctcttcagc attagcgtta tgaatgagta atataaatcg ataataccgc cgctgcgata
    72781 tgcgcgtatt ttcacccatt gacaatgttt ttggcggtgg catgatgcgc atgaaatttg
    72841 aacttcctca cggttttaat tcatgtccac gtatacccgg cctgtcatgc ttttgctgtc
    72901 tggcctgctt ttgttgactc tggcgatcgc ggtgttaaat acactcgtgc cgctttggct
    72961 cgcccaggaa cacatgtcca catggcaggt aggcgttgtc agctcatcct attttaccgg
    73021 caaccttgtc ggtacattgc tgacagggta tgtcattaag cgcattggct ttaaccgcag
    73081 ctattatctg gcctccttca tttttgccgc tggctgtgcc ggccttggcc tgatgattgg
    73141 attctggagc tggttggctt ggcgttttgt cgcgggcgtc ggctgtgcca tgatttgggt
    73201 ggttgttgag agcgcgctga tgtgcagtgg gacgtcacgt aaccgtgggc gtttgcttgc
    73261 tgcgtatatg atggtttatt acgtgggaac gtttttaggc cagttactgg tcagcaaagt
    73321 ttcaaccgag ctgatgtccg tattgccgtg ggttacaggt ttgacgttgg cagggatctt
    73381 accgctgttg tttacgcgtg tgctgaatca gcaggctgaa aaccatgatt cgacgtcaat
    73441 tacgtcaatg ctaaaactcc gtcaggcgcg gcttggcgtg aatggctgca ttatctcagg
    73501 aatcgttctg ggatctctat atggcctgat gccgctgtac ctcaatcaca aaggggtgag
    73561 caatgccagc attggtttct ggatggcggt actggtcagt gcgggtatcc ttggacaatg
    73621 gccgattgga cgtctggcgg ataagtttgg tcgactgctg gtgttgcgtg ttcaggtctt
    73681 tgtcgtcatt ctcggcagta tcgcgatgct tagccaggcg gcgatggccc cagcgttatt
    73741 catcctcggt gccgctggct ttacgctata tccggtggcg atggcatggg cttgcgagaa
    73801 agttgaacat catcaactgg tggcgatgaa ccaggcctta ctgttgagtt atactgtggg
    73861 aagtctgctt ggcccgtcat ttaccgctat gctaatgcag aatttctccg ataatttatt
    73921 gtttatcatg atcgccagcg tatcgtttat ctatttgctg atgctgctgc gcaacgccgg
    73981 tcatacgccg aaacccgttg ctcacgtgta aatgaattca agcagagtgt gaacttactg
    74041 tttcacactc tgcttttttg tttcttctat ctgacttgct ttattccaaa ttttattcgt
    74101 ttaaaaataa aatgtgcagc aggttataat tttgcatttc gctatttccg cacttcttat
    74161 ttgccgcgca taatccctcg ttttacagat gcccctttaa ttttggcgaa ggatttgtct
    74221 atggctggga atgttcagga aaaacagttg cgatggtaca acattgcgct gatgtctttt
    74281 atcactgtct ggggttttgg caacgttgtt aataactatg ccaaccaggg gctggtggtt
    74341 gttttttcat gggtgtttat ctttgcactc tatttcacac cttatgcgct aattgttggt
    74401 cagttaggct cgaccttcaa agatgggaag ggcggggtca gtacctggat taaacacacg
    74461 atgggacccg gactggctta tctcgccgcg tggacctact gggtggtgca tattccctat
    74521 ctggcacaaa aaccccaggc aattctgatt gcgctcggtt gggcgatgaa aggcgacggt
    74581 tcgctaatca aagaatattc agtcgtagcg ttacaggggt taacgctggt gctgtttatc
    74641 ttctttatgt gggttgcttc acgcggtatg aaatcgctga aaatcgtcgg ttctgtggca
    74701 gggattgcga tgtttgttat gtcgctcctg tatgtggcga tggcggtaac cgcgcctgcg
    74761 attactgaag tgcatattgc gaccacaaac attacctggg aaacgttcat tcctcatatc
    74821 gactttacct acattaccac tatttcaatg ctggttttcg cggttggcgg agcagagaag
    74881 atttctcctt acgttaatca aacgcgcaac ccaggaaaag aatttccaaa agggatgcta
    74941 tgcctggcgg tgatggttgc ggtttgtgcc attctgggct cactggcgat ggggatgatg
    75001 tttgactcgc gtaatatccc ggatgactta atgactaacg gtcaatatta cgcctttcag
    75061 aagctgggcg agtattacaa catgggtaat actttaatgg tgatttacgc cattgcgaat
    75121 accctgggac aagtagctgc gctggtattc tcgattgatg ccccgcttaa agtgctatta
    75181 ggtgatgctg acagcaaata tattccagcc agtttatgtc gtaccaacgc ttctggtacg
    75241 cccgttaatg gctattttct gaccctggtg ctggtggcaa ttctgattat gctgccgact
    75301 ctcggcatcg gtgatatgaa caatctctat aaatggctgt tgaatcttaa ctcggtagtg
    75361 atgccgctgc gttatttatg ggtatttgtt gcatttattg cagtcgttcg cctggcgcag
    75421 aaatataaac cagaatatgt ctttattcgt aataagcctc tggcaatgac cgtcgggatt
    75481 tggtgttttg cctttaccgc ctttgcctgc ttgacgggga tcttcccgaa aatggaagcc
    75541 ttcactgcag agtggacctt ccagttggcg ctgaatgttg caacgccgtt tgtgctggta
    75601 ggattaggac tgatattccc gctgctggcg cgtaaagcga atagtaaata attattgtgg
    75661 tcggtgacgc tgactctggc agatctgacc cgtttttaca taatcgagaa atgcgcgcaa
    75721 gccgcaggac atatactggc ggtttggata atagatctgg aagcctgaac gctctgtgct
    75781 ccagtcttcc agtacacatt ctaaacgacc agtatcaagg tactccttga tctgttcata
    75841 gagcagatac ccgataccag cacccatcaa aacggcctcc agttcagcat caacatcatc
    75901 cagaatgata tttcctgcga cagcaatttc cagctccttt gcaaattgcc agtggaaagg
    75961 tttgccgctg ggataacgaa aaacaacaca ttgatgatta agcagatcat gaggatggcg
    76021 gggtttgcca tatcttgcaa agtactctgg cgttgctgct acacataatt tcactggtgg
    76081 gccgatcgcc acgctgatca tatctttttc gacgatgcca ctaagtcgaa cgccagcgtc
    76141 aaagccctgt tggacgatat cgacaagaga atcgtcagtt gtgagctcga ctttaatatc
    76201 aggatattca cgtgtgaaac caaccagtaa aggcattaaa aatatacgtg cagctacccg
    76261 ggcggcattg attttgagcg ttcctgtcgg tgtcagacga aaatcattca tctcatctaa
    76321 catgatctga atttcgtcga aagctgggcg caatcgttca tagagattag aacccgcttc
    76381 cgttaacgat acgcttcggg ttgtccgatt gaataagcga attttaagac gttgttccag
    76441 tgttttaata ctatggctaa tggcggacga ggataagcct aattcatcgc ccgctgcacg
    76501 aaagctttga ttacgggcca cggcaaagaa agtggcaaag tcagacatat tcatccgcat
    76561 tagtgaaaat ccttcattaa ctcatcctga atcatcacgt ttacaggatt atgccgcctg
    76621 cgtaaagtgc gctccagaac ttaacgtgga ggtaaaatta tgcagtctga acgtatttat
    76681 ttggtatggg cccatcctcg tcatgattca ttgaccgcac atattgctga tgcgatccat
    76741 cagcgggcaa tggagcggaa aatacaggtg acggaactcg atttatatcg gcgtaatttc
    76801 aacccggtga tgacgtcgga agatgaacca gactggaaga atatggataa acgttattct
    76861 ccagaggttc atcagcttta ttcagagctg cttgaacatg acacgttagt ggtggttttt
    76921 cctctctggt ggtacagctt cccagcaatg ctaaaaggat atattgacag agtatggaat
    76981 aatgggctgg cttatggaga tgggcacaaa ttaccattca ataaagttcg ttgggtggcg
    77041 ctggttggag gagacaaaga atcatttgtc cagatgggct gggaaaaaaa tataagcgat
    77101 tatttgaaaa atatgtgcag ttatcttggt attgaagatg ccgatgtcac tttcttgtgt
    77161 aatacagtgg tattcgatgg gcaagaactt catgcgagct attatcagtc gttattatct
    77221 caggtacggg atatggtaga tgcactataa aatgtgttaa aaacgctgta gcagaatgaa
    77281 gcgcggaata aaaaagcggc aactcaataa agttgccgct ttacggggaa attagaacat
    77341 taccttatga ccgtactgct caagaatgcc tttcacgcgt tccatggtct ctttcttagg
    77401 tggtttaaca ccgtcgagtt tgtactcttc acccattgcc acccatttgt gtttgcccag
    77461 ctcgtggtag gggaggagtt cgattttctc aacgttgccc atatcacggg taaattcacc
    77521 gaggcgatgc gctgaatcgt catcgtcaga ccagcctggg acaacaacgt agcggatcca
    77581 caccttcaca tttttgttcg ccagatattt ggcgaactcc agcgtgcggt ggttggaaac
    77641 tccaaccaga ttttggtgga tctcgtcgtt catctgtttg agatcgagca ttaccaggtc
    77701 ggttacttcc agcagttcat caatcaccgg atcgtaacga cgaacaaaac cgttggtgtc
    77761 cagacaggta tgaatgcctt cttttttgca ggcgcggaac cagtcacgaa caaactcagc
    77821 ttgtaggatt gcctcaccgc cggatgcggt aacgccgccg ccggaagcgt tcataaagtg
    77881 gcgataggtc accacctctt tcattaaatc ttcaacggta acttctttac cgccatgcgt
    77941 atcccaggtg tcgcggttat gacaatacag gcagcgcatc aggcagccct ggaaaaaggt
    78001 gataaagcga atacctgggc cgtctacggt tccacaggat tcaaaggagt gaatgcgacc
    78061 aataactgac attgcggtgt ttctccagat gtggcccatc tgaggccgtg ttggtgcgca
    78121 gctcgaaggc tacgtcgagt ctgttttggc agtcacctta aagtatagat agctgacaaa
    78181 aaaggctctc gtgctaaaaa aggccccact ttcgtggagc ctttattgta cgctttttac
    78241 tgtacgattt cagtcaaatc taattacata gattgagtga aggtacgagt aataacgtcc
    78301 tgctgctgtt ctttagtcag cgagttgaaa cgtactgcgt agccagatac acggatggtc
    78361 agctgcggat atttttccgg gttttccatc gcgtcgagca gcatttcacg gttcatcacg
    78421 ttaacgttca ggtgctgacc accttcgatg gatgcttcgt ggtggaagta accatccatc
    78481 agaccagcca ggttggtctt acgaacttcg tcgtctttac ccagtgcgtt cggaacgata
    78541 gagaaggtgt aggagatacc atctttagcg taagcaaacg gcagtttagc aacggaagtc
    78601 agagacgcta cagcaccttt ctggtcacga ccgtgcatcg ggttagcacc cggtccgaac
    78661 ggcgcgccag cacgacgacc gtctggggtg ttaccagttt tcttaccata cacaacgtta
    78721 gaagtgatgg tcagaacaga ctgagtcggg atagcgtcac ggtaggtgtg cagtttctga
    78781 attttcttca tgaaacgttc taccaggtca acagccaggt catctacacg cggatcattg
    78841 ttaccaaact gcgggtattc gccttcgatt tcgaagtcga tagccagacc gtcttcgtca
    78901 cgaatcggtt taactttcgc atatttgatt gcagacaggg agtcagcagc aacggacagg
    78961 ccagcgatac cacacgccat ggtgcggata acgtcacggt cgtgcagcgc catcagagag
    79021 gcttcgtagc tgtacttgtc gtgcatgtag tggatgatgt tcagtgcagt gatgtactgt
    79081 ttagccagcc agtccatgaa gtgatccatg cgctccatca cttcatcata gttcaggaca
    79141 tcgcctttga tcggttcaga cttcggacca acctgcattt tcagtttttc gtcaacgccg
    79201 ccgttgattg cgtacagcat ggttttcgcc aggtttgcac gcgcaccgaa gaactgcatt
    79261 tgtttaccaa cgatcatcgg gcttacgcag caagcaatag cgtagtcatc gttgttgaag
    79321 tccggacgca tcaggtcatc gttctcatac tgcagagaag aggtgtcgat ggacacttta
    79381 gcggcgaatt tcttgaagtt cagcggcagt ttttcagacc acagaatggt catgttcggt
    79441 tccggagacg gacccatggt gtacagggtg ttcaggaaac ggaagctgtt tttggtaacc
    79501 agggtacgac cgtcgaggcc cataccaccg atagattcgg ttgcccagat cgggtcgcca
    79561 gagaacagtt catcgtattc cggagtacgc aggaagcgaa ccatacgcag tttcatgacc
    79621 aggtggtcaa ccatttcctg cgcttcttgt tcggtgatct tgccagcttt caggtcacgt
    79681 tcgatgtaca catccaggaa ggtggaggta cgaccgaagg acattgcagc accgttctga
    79741 gacttaacag cagccaggta gccgaagtaa gtccactgga tagcttcctg agcgttggta
    79801 gccggaccag agatgtcgta gccgtatttc gcagccattt ctttcatctg acccagagcg
    79861 cggtgctgtt cagcgatttc ttcgcgcaga cggatagtct gttccaggtt tacgccgttt
    79921 tccagatcag cctgcagaga agtgaactgt gccagtttgt ctttcatcag gtagtcgata
    79981 ccgtacagcg caacgcgacg gtagtcaccg atgatacggc cacggccata tgcatctggc
    80041 agaccggtca gaacaccaga tttacggcaa cgcaggatgt ccggagtgta aacgtcgaac
    80101 acgccctggt tgtgagtttt acggtattca gtgaagattt ttttgatcat cggatccagt
    80161 tcgcggttgt acgctttgca ggaaccttcg atcattttga taccaccgaa cgggataaga
    80221 gcacgtttca gcggagcttc agtctgcaga ccaacgattt tctcaagctg cttgttgatg
    80281 tagccagcgt cgtgagaggt gatggtggaa gcaacagcgg tgtcaaagtc aactggcgcg
    80341 tgagtgcggt tttccagttt aacgccttcc attactttgt cccacagggt ggtggtcgct
    80401 tcagtagcgc cagccaggaa ggactcgtca ccctcgtacg gagtgtagtt tttctgaatg
    80461 aagtcacgga cgtttacttc attctgccag tcacctttgg taaaaccttc ccaggctgtg
    80521 gctaactttt cattaagctc ggacatgtaa cacctacctt cttaagtgga ttttttattt
    80581 actgcgtact tcgacaacca ttaatggtgg tcgttttcac gcaggtaaat gacccagtat
    80641 gtcaacccaa ccaacaaacc accaccgata atgttgccga tcgtaaccgg aatcaggtta
    80701 tcagtgatga aattcatcac ggtcaggtga gaaaaatttt ccggtgcaga accgactgcg
    80761 gtccaaaatt ccggggatgc gaagtcgcgg attacaatac ccatcgggat cataaacatg
    80821 tttgcgatac tgtgctcaaa accgctggca acaaacatcg cgaccggcag caccataatg
    80881 aacgctttgt ccatcaggct gcggccagaa taactcatcc atactgccag acataccatc
    80941 aggtttgcca ggataccaag acagacggcc tcaataaaag tatggtgcac tttgtggtcg
    81001 gcggtttgta ggacgtttag tccccattga ccatttgcgg tcatatactc gccggaaagc
    81061 cacattaaaa gtacaaacag cagtgcgccg accaggttgc caaaatagac atttagccag
    81121 tttttcgcca actgacccca ggtgatgcgc ccactcgcct tagcaacaac aatcaacacg
    81181 gtggaagtaa agagatcggc tccgcagaca acacaaagaa tcagccccag agagaagcaa
    81241 atgccgccaa ccagttttgc catgccgaag ggcattgtgc ctgtgccagt ggttgctgtg
    81301 atatagaaga cgaatgcgat tgagatgaaa acaccggcgg taatcgccag atagaaagtc
    81361 ttaagcggat gtttcgttgc tttatagaca cccgcctctt cggccacttt ggccattgca
    81421 gcaggaagta aaagatcaaa agggttgtca gctttcacac taactctctc tttattaagt
    81481 cggcgacgag atactaacaa agcattatag atgagaaatt gatatagatc atatctcgcc
    81541 tggcttatag gcccgtaact cgcatggttt ttatgcaaat acggagtaaa tatttgatta
    81601 tccaaataaa aataaatttt aaaaattaac aaatgagttg aattttttcc gcatcctccg
    81661 ctaaaacagt taattaaaag ggagcatcag gcgaataaag taacaatatc gatcgtattt
    81721 attaaataca aattaccgat atttaacctt ataattacaa ttattttatt aatgcaaata
    81781 tatgtaaagc ggggcattaa aaaaacgccc cgtaatataa ctcagactaa tcattaagcc
    81841 tacattgcgt aggctatttg attttatttt gcccagaatg ctgctttggc gcgctgcagc
    81901 ttttcgtagg ccttcaacaa cgactgatgt gcagcaaacg cgtgcagatc gctatctacc
    81961 ggttgcaggc cgtaaaacgc cgcttcgccg ctcattgccg cactggcggc ttctacggca
    82021 tctgcgccgt acatgcgaac aaacgcattc agatattgca gcggctggcg atcttcttcc
    82081 tgtgccagta ataacaacgt ttgcaggcag cgataatagt tggcgcgttc cggactaaat
    82141 actgatgagt taaactccat cgtccattcg gtccagacca gagcctgttc cagatcgcca
    82201 ccagccagcg ccagcatggc ttttaattca ccgatacgca gggtgtacca accgttatcc
    82261 gacccggtcg ccagacccaa cagctcacgc acgcgggtaa agtcatcaaa accttcttca
    82321 tccagttgct cgatgaggtt caggtaatct tctttttccc actcgctgcc tggtagcgaa
    82381 agaatcgttt cacgtaaatg gctgcccata ctgttattcg cgagccacag atcttcagcc
    82441 ggataaatat cggacatgcc aggcacgata atgcggcaag cgtagacacc cagatgctcg
    82501 taatcggcaa tataaacttc tttatcttcc tttttgaaga tagccatcag cgtggcgaac
    82561 tcttcttccg tggtgccgga gaaattccag tccacaaacg gataatcggc atcctgcttg
    82621 aacaggtccc aggagattaa accgctggaa tcgataaagt gcgtttcgag gttggtatgt
    82681 tcagcgactt cttcatcatc gaaggttggc ggagtaaaca catccaaatc tttcaggcca
    82741 cgaccttgca gcagctcggt cacggtacgt tccagtgcta cgccaaaatc aggatgcgca
    82801 ccgaaagagg caaagcaggt accgttagca ggattgaaca gtaccacgca aatcaccgga
    82861 tactggccgc caagcgaacc gtcataagcg aagattggga aaccctccgc ttccagcgtt
    82921 tcgatggctt caactactgc tgggtaacgc gccagcacgt ctgccgggat ctctggcagg
    82981 ctgatgcttt cagcaataat gcggtttttc acgtagcgtt cgaaaacttc agacaatccc
    83041 tgaacgcgtg cttcgttgcg ggtattacct gcggacatac cgttggagac gtacaggtta
    83101 ccaatgatat tcatcggaat ataaacggtc tgattgtcgg actgacgcgt aaacggcagg
    83161 ccgcaaatac cacgatcttc gttaccggat tgtaggtcaa tcagcatgct gccggtcagt
    83221 tcattctccg gatcataaaa cgcgcgcaga cggtcatcga gtagtccttc tggcacatcg
    83281 tcattttcgg tcagtgggaa ccatttttcg ttgggataat gcacgaacgg accgttggcg
    83341 atggtttcgc ccagccagaa atcagcaaaa aagtagttgg ttgagagacg ctcgaaatat
    83401 tcaccaagtg cagaagccag cgccgctttt ttggttgcgc cttttccgtt ggtaaaacac
    83461 agtgcgcact ctttgtcgcg aatatgtaca gaccagacgt taggcacagg attcagccag
    83521 gaggcctctt caatctgaaa gccgaggtct gaaagttttt gctggaagcg agcgatggaa
    83581 tcttccagag cggcatcttt gccggggata aatgtttgcg tcatgaaaat cactttagtc
    83641 gtacggaaag cgcgcaataa tacgggtttt atctcaaagg cgctatcacc gccgccatgc
    83701 cgatgaactg ttgactatgc ttttagcgga taaaccacga taagagcata aaaatgaagg
    83761 cgttcgatct ccaccgtatg gcatttgata aagtgccttt tgatttcctt ggcgaagttg
    83821 cactacgtag tctttatacc tttgtactgg tttttttgtt cctcaaaatg accggaagac
    83881 gcggtgtgcg acagatgtcg ctgtttgaag tgttaatcat tctcacgctg ggttcagcgg
    83941 cgggagatgt ggcgttttat gatgatgtgc cgatggtgcc ggtacttatc gtctttatca
    84001 ctctggcgtt gttataccgc ctggtaatgt ggttgatggc gcacagtgaa aaactggaag
    84061 atctactgga aggtaagccg gttgttatta ttgaagatgg cgagctggcc tggtcgaaac
    84121 tcaataactc caacatgacg gaatttgagt tctttatgga gctacgattg cgtggcgtgg
    84181 agcagctggg gcaggtacgt ctggcgattc tcgaaaccaa cgggcaaatc agtgtctatt
    84241 tctttgaaga tgacaaggtg aaaccgggtt tacttatttt acccagtgat tgtacgcagc
    84301 gttacaaagt ggtgccggag tcggcggact atgcctgtat tcgttgtagt gaaatcattc
    84361 atatgaaagc gggggaaaaa caattatgtc cgcgctgtgc aaatccagaa tggacgaagg
    84421 caagtcgggc aaaacgggtg acctgacagt aaaaacatcg gctttttgct aataatccga
    84481 gagattcttt tgtgtgatgc aagccacatt tttgccctca acggttttac tcattgcgat
    84541 gtgtgtcact gaatgataaa accgatagcc acaggaataa tgtattacct gtggtcgcaa
    84601 tcgattgacc gcgggttaat agcaacgcaa cgtggtgagg ggaaatggct caaatcttca
    84661 attttagttc tggtccggca atgctaccgg cagaggtgct taaacaggct caacaggaac
    84721 tgcgcgactg gaacggtctt ggtacgtcgg tgatggaagt gagtcaccgt ggcaaagagt
    84781 tcattcaggt tgcagaggaa gccgagaagg attttcgcga tcttcttaat gtcccctcca
    84841 actacaaggt attattctgc catggcggtg gtcgcggtca gtttgctgcg gtaccgctga
    84901 atattctcgg tgataaaacc accgcagatt atgttgatgc cggttactgg gcggcaagtg
    84961 ccattaaaga agcgaaaaaa tactgcacgc ctaatgtctt tgacgccaaa gtgactgttg
    85021 atggtctgcg cgcggttaag ccaatgcgtg aatggcaact ctctgataat gctgcttata
    85081 tgcattactg cccgaatgaa accatcgacg gtatcgccat cgacgaaacg ccagacttcg
    85141 gcaaagatgt ggtggtcgcc gccgacttct cttcaaccat tctttcccgt ccgattgacg
    85201 tcagccgtta tggcgtgatt tacgctggcg cgcagaaaaa tatcggcccg gctggcctga
    85261 caatcgtcat cgttcgtgaa gatttgctgg gcaaagcgaa tatcgcgtgt ccgtcgattc
    85321 tggattattc catcctcaac gataacggct ccatgtttaa cacgccgccg acatttgcct
    85381 ggtatctatc tggtctggtc tttaaatggc tgaaagcgaa cggcggtgta gctgaaatgg
    85441 ataaaatcaa tcagcaaaaa gcagaactgc tatatggggt gattgataac agcgatttct
    85501 accgcaatga cgtggcgaaa gctaaccgtt cgcggatgaa cgtgccgttc cagttggcgg
    85561 acagtgcgct tgacaaattg ttccttgaag agtcttttgc tgctggcctt catgcactga
    85621 aaggtcaccg tgtggtcggc ggaatgcgcg cttctattta taacgccatg ccgctggaag
    85681 gcgttaaagc gctgacagac ttcatggttg agttcgaacg ccgtcacggt taatgccgaa
    85741 attttgctta atccccacag ccagcctgtg gggtttttat ttctgttgta gagagttgag
    85801 ttcatggaat ccctgacgtt acaacccatc gctcgtgtcg atggcactat taatctgccc
    85861 ggttccaaga gcgtttctaa ccgcgcttta ttgctggcgg cattagcaca cggcaaaaca
    85921 gtattaacca atctgctgga tagcgatgac gtgcgccata tgctgaatgc attaacagcg
    85981 ttaggggtaa gctatacgct ttcagccgat cgtacgcgtt gcgaaattat cggtaacggc
    86041 ggtccattac acgcagaagg tgccctggag ttgttcctcg gtaacgccgg aacggcaatg
    86101 cgtccgctgg cggcagctct ttgtctgggt agcaatgata ttgtgctgac cggtgagccg
    86161 cgtatgaaag aacgcccgat tggtcatctg gtggatgcgc tgcgcctggg cggggcgaag
    86221 atcacttacc tggaacaaga aaattatccg ccgttgcgtt tacagggcgg ctttactggc
    86281 ggcaacgttg acgttgatgg ctccgtttcc agccaattcc tcaccgcact gttaatgact
    86341 gcgcctcttg cgccggaaga tacggtgatt cgtattaaag gcgatctggt ttctaaacct
    86401 tatatcgaca tcacactcaa tctgatgaag acgtttggtg ttgaaattga aaatcagcac
    86461 tatcaacaat ttgtcgtaaa aggcgggcag tcttatcagt ctccgggtac ttatttggtc
    86521 gaaggcgatg catcttcggc ttcttacttt ctggcagcag cagcaatcaa aggcggcact
    86581 gtaaaagtga ccggtattgg acgtaacagt atgcagggtg atattcgctt tgctgatgtg
    86641 ctggaaaaaa tgggcgcgac catttgctgg ggcgatgatt atatttcctg cacgcgtggt
    86701 gaactgaacg ctattgatat ggatatgaac catattcccg atgcggcgat gaccattgcc
    86761 acggcggcgt tatttgcaaa aggcaccacc acgctgcgca atatctataa ctggcgtgtt
    86821 aaagaaaccg atcgcctgtt tgcgatggca acagaactgc gtaaagtcgg tgcggaagta
    86881 gaagaggggc acgattacat tcgtatcact ccaccggaaa aactgaactt tgccgagatc
    86941 gcgacataca atgatcaccg gatggcgatg tgtttctcgc tggtggcgtt gtcagataca
    87001 ccagtgacga ttcttgatcc caaatgtacg gccaaaacat ttccggatta tttcgagcag
    87061 ttggcgcgga ttagccaggc agcctgaatg aacaacgggc aataaatagc caaatctttc
    87121 tttatcaaaa cgtcggcaca ttgtcggcgt tttttttcgg accttgtgag tcattttgat
    87181 taatggtagc gtcgcttgtc aatgtaagtt gttgatacat aatatttata tatgattaat
    87241 caacggatga ttcacatgaa gaatactaaa ttactgctgg cgattgcgac ctctgcagca
    87301 ttactgacag ggtgtcaaaa tacccacggt attgatacca atatggctat cagctccggt
    87361 ttaaatgcct ataaagcagc aacattaagc gatgccgatg caaaagcgat tgccaatcag
    87421 ggctgtgccg aaatggacag cggcaatcaa gtcgcaagta aatccagcaa gtacggtaaa
    87481 cgtctggcaa aaatcgccaa agcattgggt aacaatatta atggcacgcc ggtcaactat
    87541 aaggtttata tgaccagcga cgtcaacgca tgggcgatgg cgaacggctg tgttcgtgtc
    87601 tacagtggcc tgatggacat gatgaatgac aacgaaattg aaggtgttct gggccatgaa
    87661 ctgggccacg tcgcgttggg gcactcgctg gctgaaatga aagcttctta tgcgatcgtt
    87721 gccgcacgcg atgccatttc agctaccagc ggtgtggctt cccagctttc ccgctcacaa
    87781 ttgggtgata tcgcagaagg cgctatcaat gctaaatact cccgtgataa agagtccgaa
    87841 gcagatgatt tctcctttga tctgttgaag aaacgtggca tcagcaccca ggggctggtt
    87901 ggcagctttg aaaaactggc tagtctggat ggcggtcgca cccagtccat gtttgactct
    87961 cacccaccat caacagagcg tgcgcaacac atccgtgatc gtatcgcctc tggtaagtaa
    88021 atcattgtca tctttcgggc tggtcttctg ccagcccgct ataattgcgc aataaatccc
    88081 catctgaata cagacaaaac tggtttttgc acacaacgtt aacgatttgt ggcgtcggcg
    88141 cgtataatgc gcgcggttat gttaacggta cgcctgtttt aaggagataa agatgacggc
    88201 aattgccccg gttattacca ttgatggccc aagcggtgca gggaaaggca ccttgtgtaa
    88261 ggctatggcg gaagcattgc aatggcatct gctggattcg ggtgcaattt atcgcgtact
    88321 ggcactagcg gcattacatc accatgttga tgttgcatcg gaagatgcgc tggtaccgct
    88381 ggcatcccac ctggatgtac gttttgtgtc aaccaatggc aatctggaag tgatcctcga
    88441 aggggaagat gtcagcggcg aaattcgtac tcaggaagtg gcgaatgcag cttcacaagt
    88501 cgcggcattc ccacgcgttc gtgaagcatt attgcgtcgc caacgcgcgt ttcgcgaatt
    88561 accaggcctg attgccgatg gccgcgacat gggaacggtg gtattccctg atgcgccagt
    88621 gaaaattttc cttgacgcct cctcggaaga acgtgcgcat cgccgcatgc tacagttgca
    88681 ggagaagggc tttagtgtta actttgagcg ccttttggcc gagatcaaag aacgcgacga
    88741 ccgcgatcgt aaccgagcgg tagcgccact ggttccggca gccgatgctt tagtgttgga
    88801 ttccaccacc ttaagcattg agcaagtgat tgaaaaagcg ctacaatacg cgcgccagaa
    88861 attggctctc gcataagcga ccgaatttgc agtacccccg ttgcaatgga atgacagcgg
    88921 gtatgttaaa caaccccatc cggcatggag ccaggtggac gttaaatata aacctgaaga
    88981 ttaaacatga ctgaatcttt tgctcaactc tttgaagagt ccttaaaaga aatcgaaacc
    89041 cgcccgggtt ctatcgttcg tggcgttgtt gttgctatcg acaaagacgt agtactggtt
    89101 gacgctggtc tgaaatctga gtccgccatc ccggctgagc agttcaaaaa cgcccagggc
    89161 gagctggaaa tccaggtagg tgacgaagtt gacgttgctc tggacgcagt agaagacggc
    89221 ttcggtgaaa ctctgctgtc ccgtgagaaa gctaaacgtc acgaagcctg gatcacgctg
    89281 gaaaaagctt acgaagatgc tgaaactgtt accggtgtta tcaacggcaa agttaagggc
    89341 ggcttcactg ttgagctgaa cggtattcgt gcgttcctgc caggttctct ggtagacgtt
    89401 cgtccggtgc gtgacactct gcacctggaa ggcaaagagc ttgaattcaa agtaatcaag
    89461 ctggatcaga agcgcaacaa cgttgttgtt tctcgtcgtg ccgttatcga atccgaaaac
    89521 agcgcagagc gcgatcagct gctggaaaac ctgcaggaag gcatggaagt taaaggtatc
    89581 gttaagaacc tcactgacta cggtgcattc gttgatctgg gcggcgttga cggcctgctg
    89641 cacatcactg acatggcctg gaaacgcgtt aagcatccga gcgaaatcgt caacgtgggc
    89701 gacgaaatca ctgttaaagt gctgaagttc gaccgcgaac gtacccgtgt atccctgggc
    89761 ctgaaacagc tgggcgaaga tccgtgggta gctatcgcta aacgttatcc ggaaggtacc
    89821 aaactgactg gtcgcgtgac caacctgacc gactacggct gcttcgttga aatcgaagaa
    89881 ggcgttgaag gcctggtaca cgtttccgaa atggattgga ccaacaaaaa catccacccg
    89941 tccaaagttg ttaacgttgg cgatgtagtg gaagttatgg ttctggatat cgacgaagaa
    90001 cgtcgtcgta tctccctggg tctgaaacag tgcaaagcta acccgtggca gcagttcgcg
    90061 gaaacccaca acaagggcga ccgtgttgaa ggtaaaatca agtctatcac tgacttcggt
    90121 atcttcatcg gcctggacgg cggcatcgac ggcctggttc acctgtctga catctcctgg
    90181 aacgttgcag gcgaagaagc agttcgtgaa tacaaaaaag gcgacgaaat cgctgcagtt
    90241 gttctgcagg ttgacgcaga acgtgaacgt atctccctgg gcgttaaaca gctcgcagaa
    90301 gatccgttca acaactgggt tgctctgaac aagaaaggcg ctatcgtaac cggtaaagta
    90361 actgcagttg acgctaaagg cgcaaccgta gaactggctg acggcgttga aggttacctg
    90421 cgtgcttctg aagcatcccg tgaccgcgtt gaagacgcta ccctggttct gagcgttggc
    90481 gacgaagttg aagctaaatt caccggcgtt gatcgtaaaa accgcgcaat cagcctgtct
    90541 gttcgtgcga aagacgaagc tgacgagaaa gatgcaatcg caactgttaa caaacaggaa
    90601 gatgcaaact tctccaacaa cgcaatggct gaagctttca aagcagctaa aggcgagtaa
    90661 ttctctgact cttcgggatt tttattccga agtttgttga gtttacttga cagattgcag
    90721 gtttcgtcct gtaatcaagc actaagggcg gctacggccg cccttaatca atgcagcaac
    90781 agcagccgct taatttgcct ttaaggaacc ggaggaatca tgaccaagtc agaattgata
    90841 gaaagacttg ccacccagca atcgcacatt cccgccaaga cggttgaaga tgcagtaaaa
    90901 gagatgctgg agcatatggc ctcgactctt gcgcagggcg agcgtattga aatccgcggt
    90961 ttcggcagtt tctctttgca ctaccgcgca ccacgtaccg gacgtaatcc gaagactggc
    91021 gataaagtag aactggaagg aaaatacgtt cctcacttta aacctggtaa agaactgcgc
    91081 gatcgcgcca atatttacgg ttaagttttt actcaaactt gaacgagaga aaagcacctg
    91141 tcgggtgctt ttttcatttc tctaatctgg aactggaagc tgcttcgcag agttttgagc
    91201 agttttcacc ctctcgttaa attcttctga acgtgcctcg gggaacgcaa aattcccacc
    91261 agacaaccgc tcaacaaagt tgcacacttt ccataaacag ggaggggtgc atgaaaataa
    91321 cgacagtcgg cgtatgcata atttgcggaa tttttccgtt gctgattttg ccccaattgc
    91381 ctgggacatt aacccttgcg tttctgacta tcttcgcctg cgtactggca tttatccctg
    91441 ttaaaaccgt acgttatatc gcgctgacgt tgctgttttt cgtttggggt atattagcgg
    91501 caaagcaaat tttgtgggca ggagaaacct taactggtgc gacgcaggat gcaattgttg
    91561 agatcactac tactgacggc atgaccactc attacggtca aatcactcat ctacaaggtc
    91621 gacgtatatt ccctgcgcca ggcctcgtgc tgtatggcga atatcttccg caagcggttt
    91681 gtgctggaca actgtggtca atgaaactca aagttcgtgc cattcatggt caacttaatg
    91741 atggcggctt tgatagccag cgttatgcca ttgcccagca tcagccgctc accggccgct
    91801 ttctgcaggc aagtgtcatt gaaccgaatt gtagcctgcg ggcacagtat ctggcgtcac
    91861 tacaaacaac gctgcaaccc tatatgtgga atgcggttat tcttggttta ggtatggggg
    91921 tacggttatc cgtccctaaa gaaatcaaaa atatcatgcg tgatactgga acggcgcatt
    91981 taatggcgat atcgggattg cacatcgctt ttgcggcgtt gctggctgcc ggactcattc
    92041 gcagtggaca aatttttctg cctgggcgct ggatccactg gcaaatacca ttaattggca
    92101 gaatctgctg tgctgctttt tatgcctggt tgacgggaat gcaacctcct gcattgcgta
    92161 ccgtggtggc gcttgctacg tggggaatgc ttaagttaag tgggcgacag tggagtggct
    92221 gggatgtatg gatatgttgt ctggcggcaa ttttgctgat ggatcctgtt gccattctct
    92281 cgcaaagttt atggctctct gccgctgcgg tcgcggcact gattttttgg taccagtggt
    92341 ttccctgtcc tgagtggcaa ctgccgccgg tattgcgtgc agttgtttcc ctcattcatt
    92401 tgcaactggg aatcacactc ctgcttatgc ccgtgcaaat cgtcatattt catggcatta
    92461 gtctgacctc gtttattgca aatctatttg caattccctt ggtgacattt atcacggttc
    92521 cgttgatcct cgccgcgatg gttgtgcatt taagcgggcc gttaatcctg gagcaagggt
    92581 tatggtttct tgccgaccgg tctttggctt tacttttctg ggggttaaag agtttgccgg
    92641 aagggtggat caacattgct gaacgttggc aatggctatc attttcccca tggttcttac
    92701 tggtggtatg gcgattaaac gcctggcgaa cgttgccagc aatgtgtgtg gctggaggct
    92761 tactgatgtg ctggccgctg tggcaaaaac ctcgacctga cgagtggcaa gtgtacatgc
    92821 ttgatgtcgg gcaagggctg gcaatggtga tagccagaaa cggcaaagcg attctctatg
    92881 acacgggact ggcctggcct gaaggggata gtgggcaaca actgattatc ccctggctcc
    92941 actggcataa tcttgaaccg gaaggcgtta ttctgagtca tgaacatctg gatcaccggg
    93001 gagggctgga ctcaatattg catacatggc cgatgttatg gatcagaagt ccgttaaact
    93061 gggaacatca tcagccctgt gtgcgtggcg aagcgtggca atggcaagga ttgcgtttca
    93121 gcgtgcactg gcctttacaa gctagcaacg ataaaggaaa taaccattcc tgtgtggtta
    93181 aggttgatga cgggatgaat agcattcttc taaccggtga tattgaagtc cccgctgaac
    93241 aaaagatgct aagccgttac tggcagcaag tgcaggcaac attgcttcag gtacctcacc
    93301 atggcagtaa tacctcatca tcgttgccat taattcagcg agtgaatgga aaagtggcac
    93361 tcgcatcggc atcgcgctat aacgcatggc gactgccctc taacaaagtt aagcatcgct
    93421 atcaacaaca gggttatacg tggctcgata ctcctcatca ggggcaagta acggtcaatt
    93481 tttcagcgca aggctggcgg attagcagtc tcagagagca aattttacct cgttggtatc
    93541 atcagtggtt tggcgtgcca gtggataacg ggtagaatat gcggctattt caacaaatgc
    93601 tggttttttg aatgcataac gacaaagatc tctctacgtg gcagacgttc cgccgactgt
    93661 ggccaaccat tgcgcctttt aaagcgggtc tgatcgtggc gggcgtagcg ttaatcctca
    93721 acgcagccag cgataccttc atgttatcgc tccttaagcc acttcttgat gatggctttg
    93781 gtaaaacaga tcgctccgtg ctggtgtgga tgccgctggt ggtgatcggg ctgatgattt
    93841 tacgtggtat caccagctat gtctccagct actgtatctc ctgggtatca ggaaaggtgg
    93901 taatgaccat gcgtcgccgc ctgtttgatc acatgatggg aatgccggtt tccttttttg
    93961 acaaacagtc aacgggtacg ctgttgtcac gtatcaccta cgattccgaa caggttgctt
    94021 cttcttcttc cggcgcactg ataacggttg tgcgtgaagg tgcgtcaatc atcggcctgt
    94081 tcatcatgat gttctattac agttggcaac tgtcgatcat tttgattgtg ctggcaccga
    94141 ttgtttcgat tgcgattcgc gttgtatcga agcgttttcg caacatcagt aaaaacatgc
    94201 agaacaccat ggggcaggtg accaccagcg ccgaacaaat gctaaagggc cacaaagaag
    94261 tattgatttt cggtggtcag gaagtggaaa cgaaacgctt cgataaagtc agcaaccgaa
    94321 tgcgtcttca ggggatgaaa atggtttcag cctcttccat ctctgatccg atcattcagc
    94381 tgatcgcctc tttggcgctg gcgtttgttc tgtatgcggc aagcttccca agtgtcatgg
    94441 atagcctgac tgccggtacg attaccgttg ttttctcttc aatgattgca cttatgcgtc
    94501 cgctgaaatc gctgaccaac gttaacgccc agttccagcg cggtatggcg gcttgtcaga
    94561 cgctgtttac cattctggac agtgagcagg agaaagacga aggtaagcgc gtgatcgagc
    94621 gtgcgacagg tgacgtggaa ttccgcaacg tcacctttac ttatccggga cgtgacgtac
    94681 ctgcattgcg taacatcaac ctgaaaattc cggcagggaa gacggttgct ctggttggac
    94741 gctctggttc aggtaaatca accatcgcca gcctgatcac gcgtttttac gatattgatg
    94801 aaggcgaaat cctgatggat ggtcacgatc tgcgcgagta taccctggcg tcgttgcgta
    94861 accaggttgc tctggtgtcg cagaatgtcc atctgtttaa cgatacggtt gctaacaaca
    94921 ttgcttacgc acgaactgaa cagtacagcc gtgagcaaat tgaagaagcg gcgcgtatgg
    94981 cctacgctat ggacttcatc aataagatgg ataacggtct cgatacagtg attggtgaaa
    95041 acggcgtgct gctctctggc ggtcagcgtc agcgtattgc tatcgctcga gccttgttgc
    95101 gtgatagccc gattctgatt ctggacgaag ctacctcggc tctggatacc gaatccgaac
    95161 gtgcgattca ggcggcactg gatgagttgc agaaaaaccg tacctctctg gtgattgccc
    95221 accgcttgtc taccattgaa aaggcagacg aaatcgtggt cgtcgaggat ggtgtcattg
    95281 tggaacgcgg tacgcataac gatttacttg agcaccgtgg cgtttacgcg caacttcaca
    95341 aaatgcagtt tggccaatga tcgaaaaaat ctggtctggt gaatcccctt tgtggcggct
    95401 attgctgcca ctctcctggt tgtatggcct ggtaagtggc gcgatccgtc tttgctataa
    95461 actaaaactg aagcgcgcct ggcgtgcccc cgtaccggtt gtcgtggttg gtaatctcac
    95521 cgcaggcggc aacggaaaaa ccccggtcgt tgtctggctg gtggaacagt tgcaacagcg
    95581 cggtattcgc gtgggggtcg tatcgcgggg atatagtggt aaggctgaat cttatccgct
    95641 gttattgtcg gcagatacca caacagcaca ggcgggtgat gaacctgtgt tgatttatca
    95701 acgcactgat gcgcctgttg cggtttctcc cgttcgttct gatgcggtaa aagccattct
    95761 ggcgcaacac cctgatgtgc agatcatcgt aaccgacgac ggtttacagc attaccgtct
    95821 ggcgcgtgat gtggaaattg tcgttattga tggtgtgcgt cgctttggca atggctggtg
    95881 gttgccggcg gggccaatgc gtgagcgagc ggggcgctta aagtcggttg atgcggtaat
    95941 cgtcaacggc ggtgtccctc gcagcggtga aatccccatg catctgctgc cgggtcaggc
    96001 ggtgaattta cgtaccggta cgcgttgtga cgttgctcag cttgaacatg tagtggcgat
    96061 ggcggggatt gggcatccgc cgcgcttttt tgccacgctg aagatgtgtg gcgtacaacc
    96121 ggaaaaatgt gtaccgctgg ccgatcatca gtctttgaac catgcggatg tcagtgcgtt
    96181 ggtaagcgcc gggcaaacgc tggtaatgac tgaaaaagat gcggtgaaat gccgggcctt
    96241 tgcagaagaa aattggtggt atttgcctgt agacgcacag ctttcaggtg atgaaccagc
    96301 gaaactgctt acgcaactaa cctcgctggc ttctggcaac tagttacgcc gcggcagcgt
    96361 tcgattgatg gagtcatgaa tgtcgctgcc gcacctctcc cttgctgatg cgcgtaatct
    96421 tcaccttgcc gcacaaggcc tgttaaacaa accccgccgt caagcgtcgt tggaggatat
    96481 tccggcaacg atctcccgca tgtccttgct gcaaatcgat accatcaata ttgttgcccg
    96541 tagtccatat ctggtgcttt tcagtcgtct gggaaattat cctgcccagt ggctggatga
    96601 gtctctggcg cgtggcgaat taatggaata ctgggcgcat gaagcctgct ttatgccgcg
    96661 tagcgacttt cgtcttattc gccaccgcat gctggcacct gaaaaaatgg gctggaaata
    96721 caaagacgcc tggatgcagg aacatgaggc ggaaattgca cagttaattc agcatattca
    96781 tgataagggg ccggtacgtt cagccgattt tgagcatcct cgtaaaggtg caagcggctg
    96841 gtgggaatgg aagccgcata aacggcatct ggaaggttta tttactgccg gaaaggtgat
    96901 ggtgattgaa cggcgcaact tccagcgcgt ttatgattta acccaccgtg tcatgcctga
    96961 ctgggatgat gagcgcgatc tcgtttcgca aacagaagca gaaatcatca tgctggataa
    97021 cagtgcgcgt agcctgggaa tattccgcga acagtggctg gcagattact atcggctgaa
    97081 acgtccggca ctggcggcgt ggcgcgaagc gagggctgaa cagcagcaaa tcattgctgt
    97141 gcatgttgaa aaattgggca atctttggct gcatgctgat ttgctgccgc tactcgagcg
    97201 tgcgctggcc ggaaagctca ctgcaacgca cagcgcggta ctttcgcctt ttgatcctgt
    97261 tgtctgggat cgcaaacgcg cagagtagct ttttgatttt agctaccggc tggagtgcta
    97321 taccccagcg ccgaaacgcc agtatggcta ttttgttctg ccattattac atcgtgggca
    97381 attagttggg cgaatggatg ccaaaatgca tcgccagaca ggcatccttg aagttatctc
    97441 tctgtggtta caggaaggca ttaaaccaac gacaatgctg caaaaagggt tacgtcaggc
    97501 gattactgat ttcgcgagct ggcagcaggc aacgcgggtg acattaggac gctgcccgca
    97561 aggtctcttt actgattgcc gcactggctg ggaaatagac cccgtcgcat aaatgattat
    97621 gataagattt atgcattcat aacccgatcc atctggagga actatggatc atcgtttgct
    97681 tgaaatcatt gcctgcccgg tttgcaacgg aaaactttgg tataaccaag aaaaacaaga
    97741 gcttatttgc aaactggata acctggcttt cccgctccgc gatggcattc cagtgttgct
    97801 ggaaacggaa gcccgcgtgc tgactgctga tgagagtaaa tcatgagttt tgtggtcatt
    97861 attcccgcgc gctacgcgtc cacgcgtctg cccggtaaac cattggttga tattaacggc
    97921 aaacccatga ttgttcatgt tcttgaacgc gcgcgtgaat caggtgccga gcgcatcatc
    97981 gtggcaaccg atcatgagga tgttgcccgc gccgttgaag ccgctggcgg tgaagtatgt
    98041 atgacgcgcg ccgatcatca gtcaggaaca gaacgtctgg cggaagttgt cgaaaaatgc
    98101 gcattcagcg acgacacggt gatcgttaat gtgcagggtg atgaaccgat gatccctgcg
    98161 accatcattc gtcaggttgc tgataacctc gctcagcgtc aggtgggtat ggcgactctg
    98221 gcggcgccaa tccacaatgc ggaagaagcg tttaacccga atgcggtgaa agtcgttctc
    98281 gacgctgaag ggtatgctct gtacttctca cgcgccacca ttccgtggga tcgtgaccgt
    98341 tttgcaaaag accttgaaac cgttggcgat aacttcctgc gtcatcttgg tatttatggc
    98401 taccgtgcag gctttatccg tcgttacgtc acctggcagc caagcccgtt agaacacatc
    98461 gaaatgttag agcagcttcg tgttctgtgg tacggcgaaa aaatccatgt tgctgttgct
    98521 caggaagttc ctggcacagg tgtggatacc cctgaagatc ttgagcgcgt tcgcgctgaa
    98581 atgcgctaat ttcacttcac gacacttcag ccaattttgg gaggagtgtc gtaccgttac
    98641 gattttcctc aatttttctt ttcaacaatt gatctcattc aggtgacatc ttttatattg
    98701 gcgctcatta tgaaagcagt agcttttatg agggtaatct gaatggaaca gctgcgtgcc
    98761 gaattaagcc atttactggg cgaaaaactc agtcgtattg agtgcgtcaa tgaaaaagcg
    98821 gatacggcgt tgtgggcttt gtatgacagc cagggaaacc caatgccgtt aatggcaaga
    98881 agctttagta cgcccggaaa agcccgacaa ctggcatgga aaaccaccat gctggcaaga
    98941 agtgggactg tccgtatgcc gactatttat ggtgtgatga cgcatgaaga acaccccggc
    99001 cctgatgtcc tgctactgga gcggatgcgt ggtgtttcgg tggaggcacc agcccgaaca
    99061 ccagaacgct gggaacagct caaagaccaa atcgttgaag ccttactggc ctggcaccgt
    99121 caggacagtc gcggttgcgt cggcgcggtc gacaatactc aggaaaattt ctggccctca
    99181 tggtacctgc aacatgttga agtgctatgg accacgctca atcagttcaa taataccggt
    99241 ctgacgatgc aggataagcg gatcctgttt cgcactcgcg aatgtctccc ggcattattt
    99301 gaaggcttta acgacaattg tgtgttgatt cacggtaact tctgtttacg cagcatgctg
    99361 aaagattcgc gcagcgatca gttactggcg atggtcgggc cgggactaat gctttgggca
    99421 ccgcgagaat acgaactgtt ccgactaatg gataattctc tggcggaaga tttgctctgg
    99481 agttacctgc aacgcgcgcc agtggcggag tcgttcatct ggcggcgttg gttgtatgtg
    99541 ttatgggatg aagttgcgca actggttaat accggacgat ttagtcggcg caacttcgat
    99601 ctggcatcaa aatcactctt gccgtggctc gcctgacgga cctttcagcc actgccagat
    99661 gcggccaagc gtttcatagc caacacgatc gctatgcatc agccagaccg gagaagggat
    99721 tgcccgttcc cacgggttaa gcggcgagtc gatggccaac tgattcgccg gggctggtag
    99781 cggatttaac ccttcctgct gaaaaaagat catcgcccgc ggcagatgtg atgcggaggt
    99841 caccagcagg aaaggggcgt caccaatcgc ctgtttcact gccgcagctt cttcttcggt
    99901 atcttttggc aaatccaggg tgataatttg ctcgcgcggc acgcccagcg attgcgcaac
    99961 tctggcacct acttccgctg tactcaccgt attggttttt gctacgcctc ctgtgaagat
   100021 cagttttgat cccggatttt cgcgccataa gcgaatacct tcattcaggc gtggcagact
   100081 gttattgatt aaattagagc tcggtgccca ctgcgggttc caggtataac cacctccgag
   100141 caccacgata tagtccactt tttgcgaatt attccatgtc ggataggtgc tttcgatggg
   100201 acgcagcagg cggtcggcta ccggttgcaa actcaataac aagagtgcca gccacccaat
   100261 gctaataaaa atcttcccgg ttttttgaaa acggctaaac cacagcagcg ccaggccagc
   100321 gccaataatt aacaacatca gcggaagtgg cagcaacata ttgccaatca cttttttcag
   100381 tgtaaaaagc atcctttctg gttccttttt taaccatata gcaagggatc gccagcgata
   100441 ttacaccaga cgggttcatt ctcgccgtgg ctgtgacaaa atagcgtctt tatcagaaaa
   100501 cgtcttagcc aaccggtgga gaaagcaatg caggatcgca attttgatga tattgcggaa
   100561 aagttttccc gtaacattta cggcaccacc aaagggcagc ttcgacaggc tattctgtgg
   100621 caggatctcg atcgcgtgct ggcggaaatg ggcccgcaaa aactgcgtgt gctggatgct
   100681 ggcggtggag aagggcagac cgcaatcaaa atggccgagc gtgggcatca ggtcatttta
   100741 tgcgatcttt ctgcgcagat gatcgaccgc gcaaaacagg cggcagaagc aaaaggtgtg
   100801 agcgacaaaa tgcaatttat acattgcgcc gctcaggatg ttgcttcgca tttggaaacg
   100861 cccgttgatc tgatattgtt ccatgcggtg ctcgagtggg tggccgatcc ccgcagtgta
   100921 ttgcagaccc tgtggtcagt gttgcgtcca ggcggcgtgt tgtcgttaat gttctacaat
   100981 gcgcatggtt tgttgatgca taacatggtc gccgggaatt ttgattacgt gcaggcggga
   101041 atgccgaaaa agaaaaaacg gacgctttcg ccagattatc cacgcgaccc ggcgcaggtt
   101101 tatctgtggc tggaagaagc tggttggcaa attatgggta agacaggcgt tcgcgtgttt
   101161 catgattatc tgcgcgagaa gcaccagcag cgcgactgct atgaagcatt acttgaatta
   101221 gaaacgcgtt attgccgtca ggaaccgtat attaccctgg ggcgttatat tcatgtcacc
   101281 gcgcgcaaac cgcagagcaa ggataaagta tgagtgaatt ttcccagaca gtccccgaac
   101341 tggttgcctg ggccagaaaa aatgacttct ccatctcgct gccggtagac cgactctctt
   101401 ttctgctggc ggttgccacg ctgaacggcg agcgtctgga tggtgagatg agtgaaggcg
   101461 agctggtgga tgcattccgc catgtgagtg atgcgtttga gcaaaccagc gaaaccatcg
   101521 gcgtgcgcgc caataacgcg atcaacgaca tggtgcgtca acgtctgctg aaccgcttta
   101581 ccagcgagca ggcggaaggg aacgcaattt accgtctgac gccgctcggc atcggcatta
   101641 ctgactacta catccgtcag cgcgagtttt ctacgctgcg tctttctatg cagttgtcga
   101701 ttgtggcggg tgaactcaaa cgcgcagctg atgccgccga agagggcggt gatgaatttc
   101761 actggcaccg taatgtctat gcgccactga aatattcggt agcagaaatt ttcgacagta
   101821 tcgacctgac gcaacgtctg atggacgaac agcagcagca ggtgaaggac gatattgccc
   101881 agttgctgaa caaagactgg cgggcggcga tttccagctg tgaattgttg ctttcagaaa
   101941 cttccggaac gctgcgtgaa ttgcaggata cgctggaagc ggcaggcgac aagttgcagg
   102001 ctaatctgtt gcgcattcag gatgcgacga tgacccatga cgacctgcat tttgtcgatc
   102061 gtctggtgtt cgatctgcag agcaaactcg accgtattat cagctggggc cagcaatcca
   102121 tcgacttgtg gattggctac gatcgccacg tacacaaatt tattcgtact gcgatcgata
   102181 tggataaaaa ccgcgtcttt gcccagcgtt tacgtcagtc ggtacaaacc tattttgatg
   102241 agccgtgggc gctaacttat gccaatgccg atcgtctgct ggatatgcgt gacgaagaga
   102301 tggcactgcg cgatgaagaa gtgactgggg aacttccgcc agatttagaa tacgaagagt
   102361 ttaacgagat ccgcgaacag ctggcggcga tcatcgaaga acaacttgct gtgtacaaaa
   102421 ccagacaagt gccgctggat cttggtctgg tggtacgcga atatctgtca cagtatccgc
   102481 gtgcacgtca ctttgacgtt gcgcgcattg ttattgatca ggcggtacgt cttggcgtag
   102541 cgcaagcaga tttcaccggg ctgccagcga aatggcagcc gattaatgat tacggagcca
   102601 aggtacaggc gcatgtcatc gacaaatatt gaacaagtga tgccggttaa gctggcgcag
   102661 gcgctggcga atccgttatt tccggcgctg gacagcgcct tacgttcagg ccgccatatt
   102721 ggcctcgacg aactggataa tcatgcattc ctgatggatt ttcaggaata tctggaagag
   102781 ttttacgcgc gttataacgt tgagcttatt cgcgcaccag aagggttctt ctatttacgc
   102841 ccacgttcca ccacgctgat ccctcgttcc gtcttgtcgg aactggatat gatggtcggg
   102901 aaaatcctct gttatctcta tctcagtccg gaacggctgg cgaatgaggg gattttcacc
   102961 cagcaggaac tgtacgacga actgctcacc ctggccgatg aagcgaaact gctgaaactg
   103021 gtgaacaacc gttcaaccgg ttcagacgtt gaccgtcaga agttgcagga gaaagtacgt
   103081 tcttcgctca accgtctgcg tcgtttaggc atggtgtggt ttatgggcca cgacagcagc
   103141 aagttccgca ttaccgaatc ggtgttccgc ttcggagccg atgtgcgtgc tggcgacgat
   103201 ccccgtgaag cacagcgtcg cctgattcgt gatggcgaag caatgccgat tgaaaatcat
   103261 ctgcaactca acgatgaaaa cgaagagaat cagccagata gcggagagga agaataatga
   103321 ttgaacgcgg taaatttcgc tcactgacgc tgattaactg gaacggcttt tttgcccgaa
   103381 cttttgacct tgacgagctg gtcacgacgc tttctggcgg taacggggcg ggtaaatcca
   103441 ccactatggc ggcgttcgtt acggcgctga tccccgacct gaccctgctg catttccgta
   103501 acactacgga agccggggcc accagcggtt cgcgcgataa aggtctgcac ggtaagctga
   103561 aagcgggtgt ctgttattcg atgctcgaca ccattaactc gcgccaccag cgcgtggtgg
   103621 tcggtgtgcg tctgcaacag gttgccggac gcgatcgtaa agtggatatc aaaccatttg
   103681 ccattcaggg actgccgatg tcggtgctgc cgacgcagct ggtgaccgaa accctgaacg
   103741 aacgccaggc gcgcgtgctg ccgcttaacg agctgaaaga caagctcgag gcgatggaag
   103801 gcgtgcagtt taaacagttc aactccatta ccgattacca ctcgctgatg ttcgatctgg
   103861 gcatcatcgc gcgtcgtctg cgctccgcat ctgaccgtag caaattctat cgtctgatcg
   103921 aagcttcgct gtatggcggg atctccagtg ccattacccg ttctctgcgc gactacctgt
   103981 tgccggaaaa cagcggcgtg cgtaaagcgt tccaggacat ggaagcggcg ctgcgtgaaa
   104041 accgcatgac gctggaagcg attcgtgtca cccagtcgga ccgtgacctg tttaagcatc
   104101 tgatcagcga agctaccaac tacgtggcgg cggactacat gcgtcacgcc aacgagcgcc
   104161 gtgtccatct cgacaaagcc ctggagtttc gtcgcgagct acatacttcg cgtcagcaac
   104221 tggcggctga gcagtacaaa cacgtcgata tggcgcgtga gctggcagag cacaacggtg
   104281 ccgaaggcga tctggaagcg gattatcagg cggccagcga tcacctgaac ctggtgcaaa
   104341 ccgcactgcg tcagcaggag aagatcgaac gctacgaagc ggatctcgat gagctgcaga
   104401 tccgtctgga agagcaaaac gaagtggtgg cagaagccat cgaacgccag gaagagaacg
   104461 aggctcgtgc ggaagctgcc gaactggaag tggacgagct gaaaagccag cttgctgact
   104521 accagcaggc gctggacgtc cagcaaacgc gcgcgatcca gtataaccag gcgattgctg
   104581 cgcttaatcg cgccaaagaa ctgtgccatc tgccggactt aaccgccgac agcgccgccg
   104641 aatggctgga aaccttccag gcgaaagagc tggaagcgac tgaaaaaatg ctctctcttg
   104701 agcagaaaat gagcatggcg caaaccgcgc acagccagtt tgagcaggct tatcagctgg
   104761 tggtggcaat caacggcccg ctggcgcgta acgaggcttg ggatgtcgcc cgcgaactgc
   104821 tgcgcgaagg ggtcgatcag cgtcacctgg cagagcaggt tcaaccgttg cggatgcgct
   104881 taagtgaact ggaacagcgt ctgcgcgagc agcaagaagc cgaacgcctg ctggcagact
   104941 tctgcaaacg tcagggcaag aattttgata ttgatgaact ggaagctctg catcaggagc
   105001 tggaagcgcg cattgcctct ctttccgata gcgtgtctaa cgcccgtgaa gagcgcatgg
   105061 cactgcgcca ggaacaggaa cagctgcagt ctcgcattca gagtttgatg cagcgtgcgc
   105121 cggtttggct ggcagcgcaa aacagtctca accagttgag cgagcagtgc ggtgaagagt
   105181 ttacctccag ccaggacgtc accgaatatc tgcaacagtt gctggagcgt gagcgagagg
   105241 cgattgttga acgcgatgaa gtgggcgcgc gcaaaaacgc tgtcgatgaa gagatcgaac
   105301 gtttaagcca gcctggcggc tctgaagatc agcgtctgaa cgcgctggcg gagcgttttg
   105361 gcggcgtgct gctgtcagaa atttatgacg acgttagcct ggaagatgcg ccgtacttct
   105421 cagcgctgta tggcccgtca cgccacgcca tcgtggtgcc agatctgtca caggtaactg
   105481 aacacctgga aggcttgacc gattgcccgg aagatctcta tttgatcgaa ggggatccgc
   105541 agtcattcga tgacagcgtg ttcagcgttg atgagctgga aaaagcggta gtggttaaaa
   105601 tcgccgatcg tcagtggcgt tattcacgtt tcccggaagt gccgctgttt ggtcgtgctg
   105661 cgcgtgaaag ccgtattgaa agcctccatg ccgagcgtga agtgctttcc gaacgcttcg
   105721 ccacgctctc ctttgatgta cagaaaactc agcgtctgca tcaggcgttc agccgcttta
   105781 tcggcagtca tctggcggtt gcgtttgagt ctgacccgga agcagaaatc cgtcaactga
   105841 acagccgtcg cgtcgaactg gagcgggcgt tgagtaatca tgaaaatgat aaccagcagc
   105901 agcgtattca gtttgagcag gcgaaagaag gcgttacggc gctgaaccgc attctgccgc
   105961 gtctcaacct gttggctgat gacagcctgg cggatcgcgt cgatgaaatc cgcgaacgtc
   106021 tggatgaagc ccaggaagcc gcgcgttttg ttcagcagtt tggcaatcaa ctggcgaaac
   106081 tggaaccgat cgtttcggta ttgcagagcg acccggaaca gttcgaacag ctaaaagaag
   106141 attacgcgta ctctcagcag atgcagcgcg atgcccgtca gcaggcgttt gccctgacgg
   106201 aagtggtgca gcgtcgtgcg cactttagct attctgactc ggcagaaatg ctgagcggta
   106261 atagcgatct caacgaaaag ctgcgtgaac gtctggaaca ggcggaagcg gagcgtactc
   106321 gcgctcgtga agcgttgcgt ggtcacgcag cgcagttgag tcagtacaac caggtgctgg
   106381 cttcgctgaa aagttcttac gacaccaaaa aagagctact caacgatctg caacgtgaat
   106441 tgcaggatat cggcgtgcgc gccgatagcg gggcagaaga gcgggcgcga attcgccgtg
   106501 acgagctgca tgcgcaactg agtaataacc ggtcccgccg caaccagctg gaaaaagcac
   106561 tgactttctg cgaagcggag atggacaatc tgacccgcaa actgcgcaag ctggagcggg
   106621 attactttga gatgcgcgag caggtagtga ccgccaaagc gggctggtgt gcagtgatgc
   106681 gcatggtgaa agataacggc gttgaacggc gcttacaccg tcgcgagctg gcttatctct
   106741 ccgctgatga tttgcgctct atgtcggata aggcattggg tgcgctgcgt ctggcggtgg
   106801 cggataacga acatctgcgc gacgtgctgc gcatgtcgga agatccaaaa cgtccggaac
   106861 gtaaaattca gttcttcgtg gcggtttatc agcatctgcg tgaacgtatt cgtcaggata
   106921 ttattcgtac cgatgatccg gtggaagcca tcgagcagat ggaaatcgaa cttagccgac
   106981 tgaccgagga gttaacctcc cgcgaacaga aactggcgat cagttcccgc agcgtggcga
   107041 acatcattcg caaaaccatt cagcgcgagc agaaccgtat ccgtatgctc aaccaggggt
   107101 tgcagaacgt atcgtttggt caggtgaaca gcgtacgtct gaacgtgaac gtgcgtgaaa
   107161 cgcacgccat gctgctggat gtgctctctg aacagcacga gcagcatcag gatctgttta
   107221 acagcaaccg tctgaccttc tcggaagcgc tggcgaaatt gtatcagcgt cttaatccgc
   107281 agattgatat ggggcagcgc gcgccgcaga ccattggcga agaactgctg gattaccgca
   107341 actatctgga aatggaagtt gaggttaacc gtggttccga tggctggttg cgcgcagagt
   107401 ctggtgcatt gtcgaccggt gaggcgattg gtaccggtat gtcgattctg gtgatggtgg
   107461 tacaaagctg ggaagatgaa tctcgccgcc tgcgcggtaa agatatctct ccttgccgcc
   107521 tgctgttcct cgatgaagca gcgcgactgg atgctcgttc tatcgccacg ctgtttgaat
   107581 tgtgtgaacg tttgcaaatg cagctcatca tcgcagcgcc ggaaaatatc agcccggaga
   107641 aaggcaccac ctataaactg gtgcgtaaag tcttccagaa taccgaacac gttcacgtcg
   107701 tcggcctgcg aggatttgcg ccgcaactcc ctgaaacgct tccaggaagt gacgaagcgc
   107761 cttctcaggc gagttaaaat taaggcggca gcaatgccgc cttttctttt tccgaaaact
   107821 ccgtttctgc actaaaaaag tggcacatta cggcgcgctt ttctttaaac ttctttacat
   107881 taggttatgt aaaaacgtat cggcgtttat atactgaaga taagcctgat gagtaacagg
   107941 cttgctcgtc atactttcgt gagtattggc gttgtacagg caagtcgtaa aataacagcc
   108001 tggctattca gagtatgata aaaacagggg gcaagggatg ttgcttaata tgatgtgtgg
   108061 tcgtcggctg tcggcaatca gtttgtgcct ggccgtaaca ttcgctccac tgttcaatgc
   108121 gcaggccgat gagcctgaag taatccctgg cgacagcccg gtggctgtca gtgaacaggg
   108181 cgaggcactg ccgcaggcgc aagccacggc aataatggcg gggatccagc cattgcctga
   108241 aggtgcggca gaaaaagccc gcacgcaaat cgaatctcaa ttacccgcag gttacaagcc
   108301 ggtttatctt aaccagcttc aactgttgta tgccgcacgc gatatgcaac ccatgtggga
   108361 aaaccgtgat gctgttaaag ccttccagca acagctggca gaggtggcga ttgccggttt
   108421 ccagccgcag tttaataaat gggtagagtt actgaccgat cctggtgtta acgggatggc
   108481 acgcgacgta gtgctctctg atgcgatgat gggctatctc catttcattg caaatattcc
   108541 ggtcaaaggc actcgctggc tatatagcag taaaccttat gcacttgcaa cgccgccgct
   108601 ctcggtgatt aaccaatggc agctggcgct ggataaaggt caattgccta cgtttgttgc
   108661 tggactggca ccgcagcatc cgcaatatgc ggcgatgcat gaatcgttac tggccttact
   108721 cagtgacacc aaaccgtggc cccaactgac cggcaaagca acgttgcgcc cagggcagtg
   108781 gagtaacgac gtaccggcgt tgcgcgaaat attgcaacgc acaggcatgt tggacggggg
   108841 gccgaaaatt actctacctg gcgatgacac gccaactgac gcggtagtca gcccatccgc
   108901 tgttactgtt gaaacagcag aaactaagcc gatggacaag caaacgacat ctcgtagtaa
   108961 acctgcgcct gccgttcgcg ccgcctacga taatgaactg gtggaagccg ttaaacgttt
   109021 tcaggcatgg caaggattgg gggcagatgg tgctattggc ccggcaacac gtgactggtt
   109081 aaacgtaacg cccgcccagc gtgctggcgt gttggctctc aacatccagc gattgcgctt
   109141 gctgccaaca gagctttcta ccgggatcat ggttaacatt ccggcctatt cgctggtcta
   109201 ctatcagaac ggcaatcagg tgctggattc gcgagtcatt gtcggtcgcc ccgatcgcaa
   109261 aacgccgatg atgagcagtg cccttaacaa cgtagtggta aacccgccgt ggaacgtacc
   109321 tccaactctg gcacgcaaag atattctgcc aaaagtgcgc aacgatccgg gatatctcga
   109381 aagccatggc tatacggtga tgcgcggctg gaacagcaga gaagcgattg acccatggca
   109441 ggttgactgg tctacaatca cggcctcgaa tttaccgttc cgcttccagc aggctccagg
   109501 cccacggaac tcgctggggc gctataaatt caatatgccg agttcagagg ccatttattt
   109561 gcatgacacg ccgaaccaca atctgttcaa gcgtgataca cgcgcattga gctcaggctg
   109621 tgtacgagtg aataaagctt ccgatctggc gaatatgctg ttgcaggatg caggctggaa
   109681 tgacaaacgt atttctgatg cgctgaagca gggtgataca cgttacgtca atattcggca
   109741 gtcgattccg gtgaatctct actacctgac ggcctttgtt ggtgcagatg gtcgtaccca
   109801 gtatcgtaca gatatttaca attatgatct gcctgcgcga tccagctcgc aaatcgtatc
   109861 gaaagcggaa caattaatca ggtaaatgaa gtagttcggg gaaatcagtt gtcgtaataa
   109921 ttagcatgat tgggggcgat tctctgcagc ccccgtcact gctggggttg agtcatcttg
   109981 acgtctgctt tacgggcggt taaggtgcct cttgtgcgcc agaagtgcat ataaacgata
   110041 acattgacct gtagacttga ttatcatgga caaattcgac gctaatcgcc gcaaattgct
   110101 ggcgcttggt ggcgttgcac tcggtgccgc catcctgccg acccctgcgt ttgcaacact
   110161 ctctacccca cgcccgcgca ttttgacact caataatctt cataccggag agtcaatcaa
   110221 agcggagttt ttcgatggca gaggctatat tcaggaagaa ttggcaaaac ttaaccattt
   110281 tttccgcgat taccgcgcga acaaaataaa gtccatcgac ccaggattat tcgaccagtt
   110341 gtatcgcctg caagggttgt taggcacgcg caaaccggtg caactcattt ccggttatcg
   110401 ttctattgat accaacaatg aactacgcgc ccgcagccgt ggagtagcga agaaaagcta
   110461 tcacactaaa ggccaggcga tggatttcca tattgaaggt atcgcgttaa gcaatattcg
   110521 caaagccgcg ttatctatgc gcgcaggtgg tgtaggatat tatccacgta gtaactttgt
   110581 gcatattgat accgggccag cacggcactg gtagtaattg cttaacgaaa caggggcagt
   110641 atgaactatc gtattattcc ggtcaccgca ttctcccaga actgttcatt aatctggtgt
   110701 gaacaaaccc gtctggccgc actggtcgat cctggcggcg atgcggaaaa aatcaaacag
   110761 gaagttgatg acagcggcct gacactgatg cagatcctgc tgacgcatgg tcatctggac
   110821 cacgttggcg cagcggcgga actggcgcaa cattacggcg tgccggtttt tggcccggaa
   110881 aaagaagatg agttctggct gcaaggcttg cctgcgcaaa gtcgtatgtt tggtctggaa
   110941 gagtgccagc cgctgacgcc agatcgttgg ctgaacgaag gcgataccat cagcataggg
   111001 aatgtgactt tacaggtgtt acattgccct gggcatacgc cgggtcatgt cgtgtttttt
   111061 gatgatcggg caaagctgct gatttctggc gatgttattt tcaaaggcgg agtagggcgc
   111121 agtgacttcc cgcgtggcga tcataatcaa ctgatttctt caatcaaaga taaattgctg
   111181 ccactggggg atgacgttac atttattccg ggtcacggac cattatccac acttggttat
   111241 gaacgcctgc ataatccctt cctgcaagac gaaatgcccg tctggtaagg cacataaaaa
   111301 agcccgcttt taatgcgggc ctggatttct ggcaaagtgc gctttgttta tgccggatgc
   111361 ggcacgagcg ccttatccgg cctacaaaat cgtgcaaatt caaaatattg caggggac
//
LOCUS       DAZUDJ010000009        92192 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.009, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000009 DAZUDJ010000000
VERSION     DAZUDJ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 92192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92192
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.009"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(195..737)
                     /locus_tag="ACHY1N_000937"
     CDS             complement(195..737)
                     /locus_tag="ACHY1N_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001502553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1133 family protein"
                     /protein_id="HFS4043280.1"
                     /translation="MIYPTNTGKSGEHLRLNTLESIWIQGKLRMWGRWSYIGGGRSGN
                     MFNQLLTSKKLTKTAINEALRRLKKAGIDKPELEAFLREMIEGKQKSWLTHCTDAEAL
                     KIDSVIGEVLADHPGLLNVLSQRYVGRGMSKRRMAELLNEQYPEWCFSTCEKRIANWL
                     AVAEYVLYIPMRESFAQKIA"
     gene            complement(734..1024)
                     /locus_tag="ACHY1N_000938"
     CDS             complement(734..1024)
                     /locus_tag="ACHY1N_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
                     /protein_id="HFS4043281.1"
                     /translation="MVDLRKAAKGQMCTVRIPGYCNHNPETSVLAHYRLAGTCGTATK
                     PHDMQAAIACSSCHDLIDGRVKTSDYTKEELRLMHAEGVFRTQEIWREKGIL"
     gene            complement(1024..1623)
                     /locus_tag="ACHY1N_000939"
     CDS             complement(1024..1623)
                     /locus_tag="ACHY1N_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1367 family protein"
                     /protein_id="HFS4043282.1"
                     /translation="MAHIQLVKQTSSGLLLPATPESCDFLHQIKIGEWIHADFKRVRN
                     YAFHKRFFKLLQLGFDYWTPNGGAITPRERELVSGFVDFLCESVGREHTPALSDAAEQ
                     YLNTVATRRTRDTALLKSFEAFREWVTIQAGFYTEHFYPDGSRGRRAKSIAFANMDET
                     EFQQVYKSVLNVLWNWILFRKFSSPEQVENVAAQLLEFA"
     gene            complement(1695..1907)
                     /locus_tag="ACHY1N_000940"
     CDS             complement(1695..1907)
                     /locus_tag="ACHY1N_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043283.1"
                     /translation="MEKIKKLFSCKYAVIRRDDLSVIVEMDYFPETPKSMMYRNGRKA
                     IFLPMRVSDIMGNDKLLDELRVRASC"
     gene            complement(2183..2338)
                     /gene="hokD"
                     /locus_tag="ACHY1N_000941"
     CDS             complement(2183..2338)
                     /gene="hokD"
                     /locus_tag="ACHY1N_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HFS4043284.1"
                     /translation="MKQQKAMLVALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVF
                     TAYEPEE"
     gene            complement(2518..3639)
                     /locus_tag="ACHY1N_000942"
     CDS             complement(2518..3639)
                     /locus_tag="ACHY1N_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4043285.1"
                     /translation="MELFDSIGNYRGDCLKLARQAKGVTGEELATALGVTRQFINKLE
                     RGYPPSSQMLTALADYLDVKESFFFTGRKSPLDSENCHFRSKRSRTQSLTNSILARAE
                     ILEQFVKCLETEIVLPELNFPDTSGLPLNSDEDIERIAEACRRYWGLGLGPISSMVNF
                     VESIGVVVAHVSGVDDRIDAFTINSKRPLIIRNSAKKSVCRFRSDLGHELGHLVLHEG
                     IITGDKITEHHADYFSSAFLVPRVSFVNEFPKMRGSHLDWNALINFKERWKISLRMCI
                     YRATVLGLITPQQMRTGFIHLNKRGTIKGEMGDELIPEEKPRLLSCAVELLDISSWKQ
                     ILDMSGVRERFVSKMFGIRRTHDDISSNIVPLYRYKDFG"
     gene            complement(3626..4276)
                     /locus_tag="ACHY1N_000943"
     CDS             complement(3626..4276)
                     /locus_tag="ACHY1N_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043286.1"
                     /translation="MPSEQNLQPCFEINPCLDEKSVINLLQQFANVLGELWFHRHEYD
                     DNWINGCRAYGWIKNFLVKNHKKLKGVAILSTPLNFVFTLNRVPLQFVTDKLDSPKKK
                     HRLCKNDVECRQLSLFEDDVNFEHDVTWRVLAEKLPSANKKDEDIEPPTWLLALIGFD
                     SSNNVVSRYELVSKVHAPVQAANTDVLPEAVETPPLNLQRRVKNAKKADSDKYGTI"
     gene            complement(4431..4625)
                     /locus_tag="ACHY1N_000944"
                     /pseudo
     CDS             complement(4431..4625)
                     /locus_tag="ACHY1N_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4658..5080)
                     /locus_tag="ACHY1N_000945"
     CDS             complement(4658..5080)
                     /locus_tag="ACHY1N_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HFS4043287.1"
                     /translation="MAKVFTPEEREKIKGQVVELVRLSGRETLRQLEEKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRANLKKTSVDDPDLIWSLPDG
                     EIRRYDRRQNIICSECRKSEVMQRALAFYQGNFQEVAQ"
     gene            complement(5096..5857)
                     /locus_tag="ACHY1N_000946"
     CDS             complement(5096..5857)
                     /locus_tag="ACHY1N_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309973.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
                     /protein_id="HFS4043288.1"
                     /translation="METVFGALKAMGKATSVELAARLDISREEVLNELWELKKAGFVD
                     KSVYTWRVADNNVQQEQPMQAELPEETTTATVAKISECDLTATIEQRGPQTADELATL
                     FGTTSRKVASTLAMAISKGRLIRVNQNGKFRYCIPGDNLPAEPKAASVAETDGKAFPQ
                     PACVALPVQEAATQEDIKTETVADIVQSLPSFTATRSDDLILSSLHMANRELRRAKNH
                     VQKWERVCAALRELNKHRDIVRQITDFSRRVASEK"
     gene            complement(5880..6626)
                     /gene="ydaV"
                     /locus_tag="ACHY1N_000947"
     CDS             complement(5880..6626)
                     /gene="ydaV"
                     /locus_tag="ACHY1N_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4043289.1"
                     /translation="MKNIATGGVLERIRRLAPPHVTAPFRTVAEWREWQLAEGQKRSE
                     EINRLNRQLRVEKILNRSGIQPLHRKCSFANYQVQNDGQRYALSQAKSIADELMTGCT
                     NFAFSGKPGTGKNHLAAAIGNRLLKDGQTVIVVTVADVMSALHASYDDGQSGEKFLRE
                     LCEVDLLVLDEIGIQRETKNEQVVLHQIVDRRTASMRSVGMLTNLNYEAMKTLLGERI
                     MDRMTMNGGRWVNFNWESWRPNVVQPGIAK"
     gene            complement(6633..7421)
                     /locus_tag="ACHY1N_000948"
     CDS             complement(6633..7421)
                     /locus_tag="ACHY1N_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043290.1"
                     /translation="MASNWIKLEVITPDKPEIFRLAEILNIDPDAALGKVIRFWAWAD
                     QQMIDGNADCNARGVTKSAIDRISFMAGFADALIQVGWLVENDVGLSLPNFERHNGKS
                     SKKRAVTNERVTKIRELKRKGNAAGVTQTDQKALPEEEEEEDLNTDLPLNPPRQKRAS
                     KKFEPEAIELPDWLPETLWHEWVRFRQALRKPIRTEQGANGAIRELEKFRQQGFTPEL
                     VIRNSIANEYQGLFAPKGVRPETLLRQVNTVSLPDSAIPPGFRG"
     gene            complement(7499..7921)
                     /gene="ydaT"
                     /locus_tag="ACHY1N_000949"
     CDS             complement(7499..7921)
                     /gene="ydaT"
                     /locus_tag="ACHY1N_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin YdaT family protein"
                     /protein_id="HFS4043291.1"
                     /translation="MKIRHEHIESVLLALAAEKGQAWVANAITDEYLRQGGGELPLVP
                     GKDWNNQQNIYHRWLKGETKAQREKIQKLIPAVLAILPRELRHRLCIFDTLERRALLA
                     AQEALSTAIDAHDDAVQAVYRKAHFSGGGSPGDSVVVH"
     gene            complement(7918..8160)
                     /locus_tag="ACHY1N_000950"
     CDS             complement(7918..8160)
                     /locus_tag="ACHY1N_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4043292.1"
                     /translation="MNKISTYRKQLGLSQRQLAVQLGWIQSRLANYEANFRTPGLEEC
                     RKIVSTLNRLGAHCGLDDVFPPDGKHSENSIGAVDS"
     gene            8257..8676
                     /locus_tag="ACHY1N_000951"
     CDS             8257..8676
                     /locus_tag="ACHY1N_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4043293.1"
                     /translation="MEKENEKIAASRLNDKIAMRLKERRQKLGLSQGKLAEICGWTQS
                     RIGNYEAGSRNVGVHDAVVLGKALGISPPELLFGEQESSELWLNESQRKLLELFNQLP
                     GSEQQRMIELFEVRLKEIDEYVEKYLRGRLKDNPPPE"
     gene            8983..9135
                     /locus_tag="ACHY1N_000952"
     CDS             8983..9135
                     /locus_tag="ACHY1N_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HFS4043294.1"
                     /translation="MDTIDLGNNESLVCGVFPNQDGTFTAMTYTKSKSFKTEAGARRW
                     LAKNTS"
     gene            9547..10395
                     /locus_tag="ACHY1N_000953"
     CDS             9547..10395
                     /locus_tag="ACHY1N_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000935589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HFS4043295.1"
                     /translation="MLDVAIENQNGWNYSAPAPHKTGAGICTPMITRAHNRAKAVFLC
                     VKRSHIQIMVGRMGPFSGGPDSLVTGSANPVRLTTHEICTSGGEFTNLSLEAAIMATI
                     PTLSHPDVTIENGRAVTTSVAVAEFFRKLHKNVIQKIEALECSSEFTELNFKPSEYTD
                     STGRKLPMYQITKNGFVFLVMGFTGKKAAAFKEAYIAEFDRMEAELRQNNTTPTNKII
                     PGDGRTLVVRFDKFGNVEFTETVPDGALVCTLDTFRLYLEKQGWTLVNRSAIKNMTVE
                     QLLSIK"
     gene            10442..10663
                     /gene="kilR"
                     /locus_tag="ACHY1N_000954"
     CDS             10442..10663
                     /gene="kilR"
                     /locus_tag="ACHY1N_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="killing protein KilR"
                     /protein_id="HFS4043296.1"
                     /translation="MIAHHFGTDEIPRQCVTPGDYVLHEGRTYIASANNIKKRKLYIR
                     SLTTKTCISDCMIKVFLGRDGLPVKAESW"
     gene            10663..10833
                     /locus_tag="ACHY1N_000955"
     CDS             10663..10833
                     /locus_tag="ACHY1N_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdaE family protein"
                     /protein_id="HFS4043297.1"
                     /translation="MTKKIKCAYHLCNKGIEESKSIKRPLHFMRGVIPTTEMKKYCSE
                     NCAEKDQMAHEL"
     gene            10914..13583
                     /gene="recE"
                     /locus_tag="ACHY1N_000956"
     CDS             10914..13583
                     /gene="recE"
                     /locus_tag="ACHY1N_000956"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051908 - double-stranded DNA 5'-3' DNA
                     exonuclease activity [Evidence IEA];
                     GO_process: GO:0090304 - nucleic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VIII"
                     /protein_id="HFS4043298.1"
                     /translation="MSTDKENYALYCDAKNDKTRKRLGIKGGFFWTEAKKLSVAVSRC
                     IAAMDDAGFDEEDFKKPIRVHLPVVNDLPPEGVFDTEFCNRYEKGGEDGITMILIAPS
                     VPDKPASTDNTNVNGEDMAKIEENMLLPVSGQILPVRWLAQHNSEKPLTHVSLDKLRA
                     LHNAQDEKLPAVTALAISNKAVQLEPLEIRDLYKLVRDTDKVFPAPVNSDLGLMTSFI
                     EAYLGADYTDRGLLTKEWMKGNRVSRISRTPSGANAGGGNITDRGEGFKHDKTSLARD
                     VATGVLARSMDVDIYNLHPAHAKRVEEIIAENKPPFSVFRDKFITMPGGLDYSRAIVV
                     ASVKEAPIGIEVIPAHVTEYLNKVLIETDHANPDPEIVDIACGRSSAPMPQRVTEEGK
                     HDGEEKPQPSCAMADKQATAETVEPDATEHHQDTQPLDAQSQVNSVDAKYQKLRAELH
                     EARKTIPPKNPVDADKLLAASRGEFVEGISDPNDPKWIKGIQTRDSVYQNQPETEQND
                     QKAEQNSPNTQQNEPETKQPEPVVQQEPEKICTACGQRSGGNCPDCGAVMGDATYQET
                     FDEENQVEAKENDPEEMEGAEHPHNENAGSDPHRDCSDETGEVADPVIVEDIEPGIYY
                     GISNENYHVGPGVSKSQLDDIADTPALYLWRKNAPVDNTKTKTLDLGTAFHCRVLEPE
                     EFSNRFIVAPEFNRRTNAGKEEEKAFLMECASTGKTVITAEEGLKIELMYQSVMALPL
                     GQWLVESAGHAESSIYWEDPETGILCRCRPDKIIPEFHWIMDVKTTADIQRFKTAYYD
                     YRYHVQDAFYSDGYEAQFGVQPTFVFLVASTTIECGRYPVEIFMMGEEAKLAGQLEYH
                     RNLRTLADCLNTNEWPAIKTLSLPRWAKEYAND"
     gene            13576..14385
                     /gene="recT"
                     /locus_tag="ACHY1N_000957"
     CDS             13576..14385
                     /gene="recT"
                     /locus_tag="ACHY1N_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecT"
                     /protein_id="HFS4043299.1"
                     /translation="MTKQPPIAKADLQKTQGNRAPAAIKNNDVISFINQPSMKEQLAA
                     ALPRHMTAERMIRIATTEIRKVPALGNCDTMSFVSAIVQCSQLGLEPGSALGHAYLLP
                     FGNKNEKSGKKNVQLIIGYRGMIDLARRSGQIASLSARVVREGDEFSFEFGLDEKLIH
                     RPGENEDAPVTHVYAVARLKDGGTQFEVMTRKQIELVRSQSKAGNNGPWVTHWEEMAK
                     KTAIRRLFKYLPVSIEIQRAVSMDEKEPLTIDPADSSVLTGEYSVIDNSEE"
     gene            14442..14636
                     /gene="ralR"
                     /locus_tag="ACHY1N_000958"
     CDS             14442..14636
                     /gene="ralR"
                     /locus_tag="ACHY1N_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system
                     endodeoxyribonuclease toxin RalR"
                     /protein_id="HFS4043300.1"
                     /translation="MRYDDVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEK
                     EALERWNKRTTGNNNGGVHV"
     gene            14629..14817
                     /locus_tag="ACHY1N_000959"
     CDS             14629..14817
                     /locus_tag="ACHY1N_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1187 family protein"
                     /protein_id="HFS4043301.1"
                     /translation="MYKITATIEKEGGTPTNWTRYSKSKLTKSECEKMLSGKKEAGVS
                     REQKVKLINFNCEKLLSS"
     gene            14917..15132
                     /gene="xisR"
                     /locus_tag="ACHY1N_000960"
     CDS             14917..15132
                     /gene="xisR"
                     /locus_tag="ACHY1N_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase XisR"
                     /protein_id="HFS4043302.1"
                     /translation="MAQVIFNEEWMVEYGLMLRTGLGARQIEAYRQNCWVEGFHFKRV
                     SPLGKPDSKRGIIWYNYPKINQFIKDS"
     gene            15134..16369
                     /gene="intR"
                     /locus_tag="ACHY1N_000961"
     CDS             15134..16369
                     /gene="intR"
                     /locus_tag="ACHY1N_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4043303.1"
                     /translation="MSKLPTGVEIRGRNIRIWFMFRGKRCRETLKGWEITNSNIKKAG
                     NLRALIVHEINSGEFEYLRRFPQSSTGAKMVTTRVIKTFGELCDIWTKIKETELTTNT
                     MKKTKSQLKTLRIIICESTPISYIRYSDILNYRNELLHGETLYLDNPRSNKKGRTVRT
                     VDNYIALLCSLLRFAYQSGFISTKPFEGVKKLQRNRIKPDPLSKTEFNALMESEKGQS
                     QNLWKFAVYSGLRHGELAALAWEDVDFEKGTVNVRRNLTILDMFGPPKTNAGIRTVTL
                     LQPALEALKVQYKLTGHHRKSEITFYHREYGRTEKQKLHFVFMPRVCNGKQKPYYSVS
                     SLGARWNAAVKRAGIRRRNPYHTRHTFACWLLTAGANPAFIASQMGHETAQMVYEIYG
                     MWIDDMNDEQVAMLNARLS"
     gene            16421..17356
                     /gene="ttcA"
                     /locus_tag="ACHY1N_000962"
     CDS             16421..17356
                     /gene="ttcA"
                     /locus_tag="ACHY1N_000962"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HFS4043304.1"
                     /translation="MQENQKNTKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGD
                     LAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK"
     gene            complement(17485..18858)
                     /gene="dbpA"
                     /locus_tag="ACHY1N_000963"
     CDS             complement(17485..18858)
                     /gene="dbpA"
                     /locus_tag="ACHY1N_000963"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="HFS4043305.1"
                     /translation="MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVR
                     VQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
                     ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
                     MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQ
                     QFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLE
                     QRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTAR
                     AGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIVPLEAEMATLCIDGGKK
                     AKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
                     CRVRLLK"
     gene            complement(18888..19061)
                     /gene="ynaL"
                     /locus_tag="ACHY1N_000964"
     CDS             complement(18888..19061)
                     /gene="ynaL"
                     /locus_tag="ACHY1N_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YnaL"
                     /protein_id="HFS4043306.1"
                     /translation="MTTLIYLQIPVPEPIPGDPVPVPDPIPRPQPMPDPPPDEEPIKL
                     SHRERRSARIRAC"
     gene            complement(19336..20319)
                     /gene="zntB"
                     /locus_tag="ACHY1N_000965"
     CDS             complement(19336..20319)
                     /gene="zntB"
                     /locus_tag="ACHY1N_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005385 - zinc ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0071577 - zinc ion transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HFS4043307.1"
                     /translation="MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLH
                     LNYVHHESAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPD
                     QLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSE
                     FIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMV
                     FLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL"
     gene            complement(20333..20380)
                     /gene="ydaN"
                     /locus_tag="ACHY1N_000966"
     CDS             complement(20333..20380)
                     /gene="ydaN"
                     /locus_tag="ACHY1N_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YnaN"
                     /protein_id="HFS4043308.1"
                     /translation="MLRNRARRLDYKIMR"
     gene            20574..21806
                     /gene="dgcM"
                     /locus_tag="ACHY1N_000967"
     CDS             20574..21806
                     /gene="dgcM"
                     /locus_tag="ACHY1N_000967"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcM"
                     /protein_id="HFS4043309.1"
                     /translation="MITHNFNTLDLLTSPVWIVSPFEEQLIYANSAARLLMQDLTFSQ
                     LRTGPYSVSSQKELPKYLSDLQNQHDIIEILTVQRKEEETALSCRLVLRELTETEPVI
                     IFEGIEAPATLGLKASRSANYQRKKQGFYARFFLTNSAPMLLIDPSRDGQIVDANLAA
                     LNFYGYNHETMCQKHTWEINMLGRRVMPIMHEISHLPGGHKPLNFVHKLADGSTRHVQ
                     TYAGPIEIYGDKLMLCIVHDITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQM
                     QHLAIAQDYSLLLIDTDRFKHINDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGE
                     EFVLLLPRTPLDTALSLAETIRVSVAKVSISGLPRFTVSIGVAHHEGNESIDELFKRV
                     DDALYRAKNDGRNRVLAA"
     gene            complement(21827..22390)
                     /gene="smrA"
                     /locus_tag="ACHY1N_000968"
     CDS             complement(21827..22390)
                     /gene="smrA"
                     /locus_tag="ACHY1N_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HFS4043310.1"
                     /translation="MNLDDKSLFLDAMEDVQPLKRATDVHWHPTRNQRAPQRIDTLQL
                     DNFLTTGFLDIIPLSQPLEFRREGLQHGVLDKLRSGKYPQQASLNLLRQPVEECRKMM
                     FSFIQQAMADGLRNVLIIHGKGRDDKSHANIVRSYVARWLTEFDDVQAYCTALPHHGG
                     SGACYVALRKTAQAKQENWERHAKRSR"
     gene            complement(22720..23628)
                     /gene="abgR"
                     /locus_tag="ACHY1N_000969"
     CDS             complement(22720..23628)
                     /gene="abgR"
                     /locus_tag="ACHY1N_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4043311.1"
                     /translation="MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELE
                     EGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELRAAQEEIRQRQGQLAGQINIGMG
                     ASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHE
                     FTFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQT
                     PQVGVVCETFSACISLVAKSDFLSILPEEMGCDPLHGQGLVMLPVSEILPKAAYYLIQ
                     RRDSRQTPLTASLITQFRRECGYLQS"
     gene            23804..25114
                     /gene="abgA"
                     /locus_tag="ACHY1N_000970"
     CDS             23804..25114
                     /gene="abgA"
                     /locus_tag="ACHY1N_000970"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgA"
                     /protein_id="HFS4043312.1"
                     /translation="MESLNQFVNSLAPKLSHWRRDFHHYAESGWVEFRTATLVAEELQ
                     QLGYSLALGREVVNESSRMGLPDELTLQREFERARQQGALAQWIAVFEGGFTGIVATL
                     DTGRPGPVMAFRVDMDALDLSEEQDVSHRPYRDGFASCNAGMMHACGHDGHTAIGLGM
                     AHTLKQFESGLHGVIKLIFQPAEEGTRGARAMVDAGVVDDVDYFTAVHIGTGVPAGTV
                     VCGSDNFMATTKFDAHFTGTAAHAGAKPEDGHNALLAAAQATLALHAIAPHSEGASRV
                     NVGVMQAGSGRNVVPASALLKVETRGASDVINQYVFDRAQQAIQGAATMYGVGVETRL
                     MGAATASSPSPQWVAWLQSQAAQVAGVNQAIERVEAPAGSEDATLMMARVQQHQGQAS
                     YVVFGTQLAAGHHNEKFDFDEQVLAIAVETLARTALNFPWTRGI"
     gene            25114..26559
                     /gene="abgB"
                     /locus_tag="ACHY1N_000971"
     CDS             25114..26559
                     /gene="abgB"
                     /locus_tag="ACHY1N_000971"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgB"
                     /protein_id="HFS4043313.1"
                     /translation="MQEIYRFIDDAIEADRQRYTDIADQIWDHPETRFEEFWSAEHLA
                     SALESASFTVTRNVGNIPNAFIASFGQGKPVIALLGEYDALAGLSQQAGCAQPTSATP
                     GENGHGCGHNLLGTAAFAAAIAVKKWLEQYGQGGTVRFYGCPGEEGGSGKTFMVREGV
                     FDDVDAALTWHPEAFAGMFNTRTLANIQASWCFKGIAAHAANSPHLGRSALDAVTLMT
                     TGTNFLNEHIIEKARVHYAITNSGGISPNVVQAQAEVLYLIRAPEMTDVQHIYDRVAK
                     IAEGAALMTETTVECRFDKACSSYLPNRTLENAMYHALSHFGTPEWNSEELAFAKQIQ
                     ATLTPNDRQNSLNNIAATGGENGKVFALRHRETVLANEVAPYAATDNVLAASTDVGDV
                     SWKLPVAQCFSPCFAVGTPLHTWQLVSQGRTSIAHKGMLLAAKTMAATTVNLFIDSGL
                     LQECQQEHQQVTDTQPYHCPIPKNVTPSPLK"
     gene            26593..28119
                     /gene="abgT"
                     /locus_tag="ACHY1N_000972"
     CDS             26593..28119
                     /gene="abgT"
                     /locus_tag="ACHY1N_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate transporter"
                     /protein_id="HFS4043314.1"
                     /translation="MSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTT
                     AILSAFGVSAKNPTDGTPVVVKNLLSVEGLHWFLPNVIKNFSGFAPLGAILALVLGAG
                     LAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIMPPMGALIFLAVG
                     RHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEAAAAFNPQMHVSVIDNWYFMA
                     SSVVVLTIVGGLITDKIIEPRLGQWQGNSDEKLQTLTESQRFGLRIAGVVSLLFIAAI
                     ALMVIPENGILRDPINHTVMPSPFIKGIVPLIILFFFVVSLAYGIATRTIRRQADLPH
                     LMIEPMKEMAGFIVMVFPLAQFVAMFNWSNMGKFIAVGLTDILESSGLSGIPAFVGLA
                     LLSSFLCMFIASGSAIWSILAPIFVPMFMLLGFHPAFAQILFRIADSSVLPLAPVSPF
                     VPLFLGFLQRYKPDAKLGTYYSLVLPYPLIFLVVWLLMLLAWYLVGLPIGPGIYPRLS
                     "
     gene            28130..28645
                     /gene="ogt"
                     /locus_tag="ACHY1N_000973"
     CDS             28130..28645
                     /gene="ogt"
                     /locus_tag="ACHY1N_000973"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFS4043315.1"
                     /translation="MLRLLEEKIATPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDI
                     HYRKEGYERISATNPGGLSDKLRDYFAGNLSIIDTLPTATGGTPFQREVWKTLRTIPC
                     GQVMHYGQLAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKE
                     WLLRHEGYLLL"
     gene            28840..29592
                     /gene="fnr"
                     /locus_tag="ACHY1N_000974"
     CDS             28840..29592
                     /gene="fnr"
                     /locus_tag="ACHY1N_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HFS4043316.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENNDALAQLAGHTRNVA"
     gene            29744..30694
                     /gene="uspE"
                     /locus_tag="ACHY1N_000975"
     CDS             29744..30694
                     /gene="uspE"
                     /locus_tag="ACHY1N_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HFS4043317.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQ
                     EVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGI
                     SAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD"
     gene            complement(30744..31001)
                     /gene="ynaJ"
                     /locus_tag="ACHY1N_000976"
     CDS             complement(30744..31001)
                     /gene="ynaJ"
                     /locus_tag="ACHY1N_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HFS4043318.1"
                     /translation="MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIP
                     LSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ"
     gene            31245..32276
                     /gene="ynaI"
                     /locus_tag="ACHY1N_000977"
     CDS             31245..32276
                     /gene="ynaI"
                     /locus_tag="ACHY1N_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low conductance mechanosensitive channel YnaI"
                     /protein_id="HFS4043319.1"
                     /translation="MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHA
                     VQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFE
                     KQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAG
                     KDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKITTFDNRPLYVPN
                     SLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLV
                     YFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMD
                     NITPQEQGR"
     gene            complement(32327..33940)
                     /gene="mppA"
                     /locus_tag="ACHY1N_000978"
     CDS             complement(32327..33940)
                     /gene="mppA"
                     /locus_tag="ACHY1N_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide ABC transporter
                     substrate-binding protein MppA"
                     /protein_id="HFS4043320.1"
                     /translation="MKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDE
                     PASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNA
                     KWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTA
                     VDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERV
                     VNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKL
                     LKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPA
                     WHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQ
                     KIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLL
                     TSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAPIAPIYQYTNG
                     RLIKPWLKGYPINNPEDVAYSRTMYIVKH"
     gene            complement(34277..35176)
                     /gene="pgrR"
                     /locus_tag="ACHY1N_000979"
     CDS             complement(34277..35176)
                     /gene="pgrR"
                     /locus_tag="ACHY1N_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator PgrR"
                     /protein_id="HFS4043321.1"
                     /translation="MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEE
                     RLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDSAMASLSDLQNRPSGTIRITTVE
                     HAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
                     GPDIPMAIVGSPDYFSRRSVPTSVSQLIDHQAINLYLPTSGKANRWRLIRGGREVRVR
                     MEGQLLLNTIDLIIDAAIDGHGLAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYY
                     PHRRHAGSAFSLFIDRLKYKGAV"
     gene            35314..36234
                     /locus_tag="ACHY1N_000980"
     CDS             35314..36234
                     /locus_tag="ACHY1N_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415843.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4043322.1"
                     /translation="MMNNKVSFTNSNNPTISLSAVIYFPPKFDETRQYQAIVLSHPGG
                     GVKEQTAGTYAKKLAEKGFVTIAYDASYQGESGGEPRQLENPYIRTEDISAVIDYLTT
                     LSYVDNTRIGAMGICAGAGYTANAAIQDRRIKAIGTVSAVNIGSMFRNGWENNVKSID
                     ALPYVEAGSNARTSDISSGEYAVMPLAPMKESDAPNEELRQAWEYYHTPRAQYPTAPG
                     YATLRSLNQIITYDAYHMAEVYLTQPMQIVAGSQAGSKWMSDDLYDRASSQDKRYHIV
                     EGANHMDLYDGKAYVAEAISVLAPFFEETL"
     gene            36234..37166
                     /locus_tag="ACHY1N_000981"
     CDS             36234..37166
                     /locus_tag="ACHY1N_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4043323.1"
                     /translation="MKHIQIRNSDMAWHIAANIQFPPNFDESKQYPAIISVHPFGSCK
                     EQTFGNIYGKALAEKGYLVLAYDASFQGESGGEPRWIEDPTQRVEDISRVIDYAVTLP
                     YVNAERIGVLGVCGGGGYAINAALTEKRIKAVVSITGVNIGRLFREGFSNYDPIGALN
                     AMASQRTKEARGGELQINELLPASLDAAKAHGVTERDVYEATDYYKTPRGQQPGGATK
                     MLFSHAQKTLAWDAFAFTEVLLTQPVMVVVGEKVGAFGAYRDGLEVYGRAMVSQDRQL
                     VSLPDFSHYELYDKPEAVQEALEKVIPFFNTHLG"
     gene            37184..37822
                     /locus_tag="ACHY1N_000982"
     CDS             37184..37822
                     /locus_tag="ACHY1N_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309933.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4043324.1"
                     /translation="MKNVLILGAGGQIARHVINQLADKQTIKQTLFARQPAKIHKPYP
                     TNSKIIMGDVLNHAALKQAMQGQDVVYANLTGEDLDIQANSVIAAMKACDVKRLIFVL
                     SLGIYDEVPGKFGEWNNAVIGEPLKPFRRAADAIEASGLEYTILRPAWLTDEDIIDYE
                     LTSRNEPFKGTIVSRKSVAALITDIIDKPEKHIGDNIGINQPVTDGDKPLFM"
     gene            38131..38859
                     /gene="mpaA"
                     /locus_tag="ACHY1N_000983"
     CDS             38131..38859
                     /gene="mpaA"
                     /locus_tag="ACHY1N_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415842.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HFS4043325.1"
                     /translation="MTVNRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLI
                     LAGTHGDENSSVVTLSCALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFP
                     AANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
                     ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDE
                     ASEKYLFAMANLLRWHPKDAIRPS"
     gene            complement(38834..39799)
                     /gene="ycjG"
                     /locus_tag="ACHY1N_000984"
     CDS             complement(38834..39799)
                     /gene="ycjG"
                     /locus_tag="ACHY1N_000984"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016855 - racemase and epimerase activity,
                     acting on amino acids and derivatives [Evidence IEA];
                     GO_process: GO:0009063 - amino acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HFS4043326.1"
                     /translation="MRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEEEGIKGTGE
                     CTPYPRYGESDASVMAQIMSVVSQLEKGLTREELQKILPAGAARNALDCALWDLAARK
                     QQQSLADLIGITLPETVITAQTVVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISER
                     MVAIRTAVPDATLIVDANESWRAEGLAARCQLLADLGVAMLEQPLPAQDDAALENFIH
                     PLPICADESCHTRSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFSLMLGCM
                     LCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL"
     gene            39918..40424
                     /gene="tpx"
                     /locus_tag="ACHY1N_000985"
     CDS             39918..40424
                     /gene="tpx"
                     /locus_tag="ACHY1N_000985"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HFS4043327.1"
                     /translation="MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFA
                     GKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNN
                     VITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
                     AALAVLKA"
     gene            complement(40468..42009)
                     /gene="tyrR"
                     /locus_tag="ACHY1N_000986"
     CDS             complement(40468..42009)
                     /gene="tyrR"
                     /locus_tag="ACHY1N_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HFS4043328.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFA
                     ELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKV
                     DMANPASCQLFAQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLME
                     ITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVE
                     QAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRAGKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVR
                     VICATQKNLVELVQKGMFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKNEE"
     gene            complement(42157..43218)
                     /gene="ycjF"
                     /locus_tag="ACHY1N_000987"
     CDS             complement(42157..43218)
                     /gene="ycjF"
                     /locus_tag="ACHY1N_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjF family protein"
                     /protein_id="HFS4043329.1"
                     /translation="MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDE
                     APEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIIGAGVGTVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQ
                     QAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRR
                     QLIGQVKETLQKGKTPSEK"
     gene            complement(43215..44612)
                     /gene="ycjX"
                     /locus_tag="ACHY1N_000988"
     CDS             complement(43215..44612)
                     /gene="ycjX"
                     /locus_tag="ACHY1N_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HFS4043330.1"
                     /translation="MKRLKNELNALVNRGVDRHLRLAVTGLSRSGKTTFITAMVNQLL
                     NIHAGARLPLLSAVREERLLGVKRIPQRDFGIPRFTYDEGLAQLYGDPPAWPTPTRGV
                     SEIRLALRFKSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMTGLL
                     NGQRGEWSVKWRMMCEGLDPLAPADENRLADIAAAWTDYLHHCKQQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDAWGESKLAQADKHTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTIDQHANMVSLLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGIIDVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPARLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            44767..45765
                     /gene="ycjW"
                     /locus_tag="ACHY1N_000989"
     CDS             44767..45765
                     /gene="ycjW"
                     /locus_tag="ACHY1N_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4043331.1"
                     /translation="MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEEL
                     QYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFFSEVLHAITAKAEEEGFDVILQT
                     SHNPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYDIPVVVIGKVEGQYAHV
                     YSVDTDNFGDSIALTDALIESGHQNIACLHAPLDVHVSVDRVNGYKQSLAAHNIAVRD
                     EWIVDGGYTHETALQAARELLSQSPLPEAVFATDSLKLMSIYRAAAEKNIAIPQQLAV
                     VGYSNETLSFILTPAPGGIDIPTQELGQQSCELLFRLISGKPSPQNITVATHMTLK"
     gene            complement(45876..46781)
                     /gene="ompG"
                     /locus_tag="ACHY1N_000990"
     CDS             complement(45876..46781)
                     /gene="ompG"
                     /locus_tag="ACHY1N_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monomeric porin OmpG"
                     /protein_id="HFS4043332.1"
                     /translation="MKKLLPCTALVMCAGMACAQAEERNDWHFNIGAMYEIENVEGYG
                     EDMDGLAEPSVYFNAANGPWRIALAYYQEGPVDYSAGKRGTWFDRPELEVHYQFLEND
                     DFSFGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFAN
                     DLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYL
                     PLTLGNHSVTPYTRIGLDRWSNWDWQDDIEREGHDFNRVGLFYGYDFQNGLSVSLEYA
                     FEWQDHDEGDSDKFHYAGVGVNYSF"
     gene            complement(46826..47908)
                     /locus_tag="ACHY1N_000991"
     CDS             complement(46826..47908)
                     /locus_tag="ACHY1N_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4043333.1"
                     /translation="MAQLSLQHIQKIYDNQVHVVKDFNLEIADKEFIVFVGPSGCGKS
                     TTLRMIAGLEEISGGDLLIDGKRMNDVPAKARNIAMVFQNYALYPHMTVYDNMAFGLK
                     MQKIAKEVIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDE
                     PLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGA
                     PKTVYNQPANMFVAGFIGSPAMNFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQGSLH
                     KPIVMGIRPEDIHPDAQEENNISAKISVAELTGAEFMLYTTVGGHELVVRAGALNDYH
                     AGENITIHFDMTKCHFFDAETEIAIR"
     gene            complement(47922..48581)
                     /gene="pgmB"
                     /locus_tag="ACHY1N_000992"
     CDS             complement(47922..48581)
                     /gene="pgmB"
                     /locus_tag="ACHY1N_000992"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFS4043334.1"
                     /translation="MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESL
                     KGISRDESLRRILQHGGKEGDFNSQERAQLAYRKNLLYVHSLRELTVSAVLPGIRSLL
                     ADLRAQQIPVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
                     GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTDSLTWSRLSAFWQN
                     V"
     gene            complement(48578..50845)
                     /gene="ycjT"
                     /locus_tag="ACHY1N_000993"
     CDS             complement(48578..50845)
                     /gene="ycjT"
                     /locus_tag="ACHY1N_000993"
                     /EC_number="2.4.1.230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kojibiose phosphorylase"
                     /protein_id="HFS4043335.1"
                     /translation="MTRPVTLSEPHFSQHTLNKYASLMAQGNGYLGLRASHEEDYTRQ
                     TRGMYLAGLYHRAGKGEINELVNLPDILGMEIAINGEVFSLSREAWQRELDFASGELR
                     RSVVWRTSNGTGYTIASRRFVSADQLPLIVLEITITPLDADASVLISTGIDATQTNHG
                     RQHLDETQVRVFGQHLMQGIYTTQDGRSDVAISCCCMVSGDVQQCYTAKERRLQQHTS
                     AQLHAGETVTLQKLVWIDWRDDRQAVLDEWGSASLRQLEMCAQQSYDQLLAVSTENWR
                     QWWQKRRITVNGGEAHDQQALDYALYHLRIMTPAHDERSSIAAKGLTGEGYKGHVFWD
                     TEVFLLPFHLFSDPTVARSLLRYRWHNLPGAQEKARRNGWQGALFPWESARSGEEETP
                     EFAAINIRTGLRQKVASAQAEHHLVADIAWAVIQYWQTTGDESFIAHEGMALLLETAK
                     FWISRAVRVNDRLEIHDVIGPDEYTEHVNNNAFTSYMAYYNVQQALSIARQFGCSDDA
                     FIHRAEMFLKELRLPEIQPDGVLPQDDSFMAKPAINLAKYKAAAGKQTILLDYSRAEV
                     NEMQILKQADVVMLNYMLPEQFSAASCLANLQFYEPRTIHDSSLSKAIHGIVAARCGL
                     LTQSYQFWREGTEIDLGADPHSCDDGIHAAATGAIWLGAIQGFAGVSVRDGELHLNPA
                     LPEQWQQLSFPLFWQGCELQVTLDAQRIAIRTSAPVSLRLNGQLISVAEESVFCLGDF
                     ILPFNGTATTHQEDE"
     gene            complement(50842..51897)
                     /gene="ycjS"
                     /locus_tag="ACHY1N_000994"
     CDS             complement(50842..51897)
                     /gene="ycjS"
                     /locus_tag="ACHY1N_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4043336.1"
                     /translation="MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSR
                     LSQAQALADKYGNASVWDDPQAMLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCE
                     KPPAMTPEQAREMCDTARKLGKVLAYDFHHRFALDTQQLREQVTNGVLGEIYVTTARA
                     LRRCGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGFPAVKSVNAHSFQKIGTQK
                     SCGQFGEWDPATYSVEDSLFGTIEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGA
                     TLFPAHIYTDNNGELMTLMQRELADDNRHLRSMEAFINHVQGKPVMIADAEQGYIIQQ
                     LVAALYQSAETGTRVEL"
     gene            complement(51907..52695)
                     /gene="ycjR"
                     /locus_tag="ACHY1N_000995"
     CDS             complement(51907..52695)
                     /gene="ycjR"
                     /locus_tag="ACHY1N_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFS4043337.1"
                     /translation="MKIGTQNQAFFPENILEKFRYIKEMGFDGFEIDGKLLVNNLEEV
                     KAAIKETGLPVTTACGGYDGWIGDFIEERRLNGLKQIERILEALAEVGGKGIVVPAAW
                     GMFTFRLPPMTSPRSLDGDRKMVSDSLHVLEQVAARTGTVVYLEPLNRYQDHMINTLA
                     DARRYIVENDLKHVQIIGDFYHMNIEEDNLAQALHDNRDLLGHVHIADNHRYQPGSGT
                     LDFHALFEQLRADNYQGYVVYEGRIRAEDPAQAYRDSLAWLRTC"
     gene            complement(52713..53765)
                     /gene="ycjQ"
                     /locus_tag="ACHY1N_000996"
     CDS             complement(52713..53765)
                     /gene="ycjQ"
                     /locus_tag="ACHY1N_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFS4043338.1"
                     /translation="MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVD
                     FRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVG
                     DSVCGYGPLSETVIINAVNNYKLRKMPEGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
                     VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAYRCDIARRHGADFCLNPIGTDVGKEI
                     KTLTGKQGADVIIETSGYADALQSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNN
                     AKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLIDPVVTFAKSPESYMQ
                     YVDQHPEQSIKMGVTF"
     gene            complement(53796..54638)
                     /gene="ycjP"
                     /locus_tag="ACHY1N_000997"
     CDS             complement(53796..54638)
                     /gene="ycjP"
                     /locus_tag="ACHY1N_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4043339.1"
                     /translation="MATNKRTLSRIGFYCGLALFLIITLFPFFVMLMTSFKGAKEAIS
                     LHPTLLPQQWTLEHYVDIFNPMIFPFVDYFRNSLVVSVVSSVVAVFLGILGAYALSRL
                     RFKGRMTINASFYTVYMFSGILLVVPLFKIITALGIYDTEMALIITMVTQTLPTAVFM
                     LKSYFDTIPDEIEEAAMMDGLNRLQIIFRITVPLAMSGLISVFVYCFMVAWNDYLFAS
                     IFLSSASNFTLPVGLNALFSTPDYIWGRMMAASLVTALPVVIMYALSERFIKSGLTAG
                     GVKG"
     gene            complement(54625..55506)
                     /gene="ycjO"
                     /locus_tag="ACHY1N_000998"
     CDS             complement(54625..55506)
                     /gene="ycjO"
                     /locus_tag="ACHY1N_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4043340.1"
                     /translation="MNRLFSGRSDMPFALLLLAPSLLLLGGLVAWPMVSNIEISFLRL
                     PLNPNIESTFVGVSNYVRILSDPGFWHSLWMTVWYTALVVAGSTVLGLAVAMFFNREF
                     HLRKTARSLVILSYVTPSISLVFAWKYMFNNGYGIVNYLGVDLLHLYEQAPLWFDNPG
                     SSFVLVVLFAIWRYFPYAFISFLAILQTIDKSLYEAAEMDGANAWQRFRIVTLPAIMP
                     VLATVVTLRTIWMFYMFADVYLLTTKVDILGVYLYKTAFAFNDLGKAAAISVVLFIII
                     FAVILLTRKRVNLNGNK"
     gene            complement(55527..56819)
                     /gene="ycjN"
                     /locus_tag="ACHY1N_000999"
     CDS             complement(55527..56819)
                     /gene="ycjN"
                     /locus_tag="ACHY1N_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4043341.1"
                     /translation="MIKSKIVLLSALVSCALISGCKEENKTNVSIEFMHSSVEQERQA
                     VISKLIARFEKENPGITVKQVPVEEDAYNTKVITLSRSGSLPEVIETSHDYAKVMDKE
                     QLIDRKAVATVISNVGEGAFYDGVLRIVRTEDGSAWTGVPVSAWIGGIWYRKDVLAKA
                     GLEEPKNWQQLLDVAQKLNDPANKKYGIALPTAESVLTEQSFSQFALSNQANVFNAEG
                     KITLDTPEMMQALTYYRDLAANTMPGSNDIMEVKDAFMNGTAPMAIYSTYILLAVIKE
                     GDPKNVGFVVPTEKNSAVYGMLTSLTITAGQKTEETEAAEKFVTFMEQADNIADWVMM
                     SPGAALPVNKAVVTTATWKDNDVIKALGELPNQLIGELPNIQVFGAVGDKNFTRMGDV
                     TGSGVVSSMVHNVTVGKADLPGTLQASQKKLDELIEQH"
     gene            complement(56833..58512)
                     /gene="ycjM"
                     /locus_tag="ACHY1N_001000"
     CDS             complement(56833..58512)
                     /gene="ycjM"
                     /locus_tag="ACHY1N_001000"
                     /EC_number="2.4.1.352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415825.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosylglycerate phosphorylase"
                     /protein_id="HFS4043342.1"
                     /translation="MKQKITDYLDEIYGGTFTATHLQKLVTRLESAKRLITQRRKKHW
                     DESDVVLITYADQFHSNDLKPLPTFNQFYHQWLQSIFSHVHLLPFYPWSSDDGFSVID
                     YHQVASEAGEWQDIQQLGECSHLMFDFVCNHMSAKSEWFKNYLQQHPGFEDFFIAVDP
                     QTDLSAVTRPRALPLLTPFQMRDHSTRHLWTTFSDDQIDLNYRSPEVLLAMVDVLLCY
                     LAKGAEYVRLDAVGFMWKEPGKSCIHLEKTHLIIKLLRSIIDNVAPGTVIITETNVPH
                     KDNIAYFGAGDDEAHMVYQFSLPPLVLHAVQKQNVEALCAWAQNLTLPSSNTTWFNFL
                     ASHDGIGLNPLRGLLPESEILELVEALQQEGALVNWKNNPDGTRSPYEINVTYMDALS
                     RRESSDEERCARFILAHAILLSFPGVPAIYIQSILGSRNDYAGVEKLGYNRAINRKKY
                     HSKEITRELNDEATLRHAVYHELSRLITLRRSHNEFHPDNNFTIDTINSSVMRIQRSN
                     ADGNCLTGLFNVSKNIQHVNITNLHGRDLISEVDILGNEITLRPWQVMWIK"
     gene            complement(58725..59039)
                     /gene="pspE"
                     /locus_tag="ACHY1N_001001"
     CDS             complement(58725..59039)
                     /gene="pspE"
                     /locus_tag="ACHY1N_001001"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HFS4043343.1"
                     /translation="MFKKGLLALALVFSLPVFAAEHWIDVRVPEQYQQEHVQGAINIP
                     LKEVKERIATAVPDKNDTVKVYCNAGRQSGQAKEILSEMGYTHVENAGGLKDIAMPKV
                     KG"
     gene            complement(59114..59335)
                     /gene="pspD"
                     /locus_tag="ACHY1N_001002"
     CDS             complement(59114..59335)
                     /gene="pspD"
                     /locus_tag="ACHY1N_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HFS4043344.1"
                     /translation="MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVA
                     RRPLKMLLAVALEPLLSRAANKLAQRYKR"
     gene            complement(59344..59703)
                     /gene="pspC"
                     /locus_tag="ACHY1N_001003"
     CDS             complement(59344..59703)
                     /gene="pspC"
                     /locus_tag="ACHY1N_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HFS4043345.1"
                     /translation="MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPAKLVRILVVLS
                     IFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSSSELLDEVDRELAASETRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            complement(59703..59927)
                     /gene="pspB"
                     /locus_tag="ACHY1N_001004"
     CDS             complement(59703..59927)
                     /gene="pspB"
                     /locus_tag="ACHY1N_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009271 - phage shock [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HFS4043346.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLA
                     QLADEAKRMRERIQALESILDAEHPNWRDR"
     gene            complement(59981..60649)
                     /gene="pspA"
                     /locus_tag="ACHY1N_001005"
     CDS             complement(59981..60649)
                     /gene="pspA"
                     /locus_tag="ACHY1N_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HFS4043347.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     STSARALAEKKQLTRRIEQASAREVEWQEKAELALLKEREDLARAALIEKQKLTDLIK
                     SLEHEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEAEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMK
                     QDNQ"
     gene            60816..61793
                     /gene="pspF"
                     /locus_tag="ACHY1N_001006"
     CDS             60816..61793
                     /gene="pspF"
                     /locus_tag="ACHY1N_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HFS4043348.1"
                     /translation="MAEYKDNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKEL
                     IASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGT
                     FRADLLDRLAFDVVQLPPLRERESDIMLMAEHFAIQMCREIKLPLFPGFTERARETLL
                     NYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKRRPPEDAIAVSETTSLPTLP
                     LDLREFQMQQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI"
     gene            complement(61913..63178)
                     /gene="puuE"
                     /locus_tag="ACHY1N_001007"
     CDS             complement(61913..63178)
                     /gene="puuE"
                     /locus_tag="ACHY1N_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003867 - 4-aminobutyrate transaminase
                     activity [Evidence IEA];
                     GO_process: GO:0009448 - gamma-aminobutyric acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate transaminase"
                     /protein_id="HFS4043349.1"
                     /translation="MSNNEFHQRRLSATPRGVGVMCNFFAQSAENATLKDVEGNEYID
                     FAAGIAVLNTGHRHPDLVAAVEQQLQQFTHTAYQIVPYESYVTLAEKINALAPVSGQA
                     KTAFFTTGAEAVENAVKIARAHTGRPGVIAFSGGFHGRTYMTMALTGKVAPYKIGFGP
                     FPGSVYHVPYPSDLHGISTQDSLDAIERLFKSDIEAKQVAAIIFEPVQGEGGFNVAPK
                     ELVAAIRRLCDEHGIVMIADEVQSGFARTGKLFAMDHYADKPDLMTMAKSLAGGMPLS
                     GVVGNANIMDAPAPGGLGGTYAGNPLAVAAAHAVLNIIDKESLCERANQLGQRLKNTL
                     IDAKESVPAIAAVRGLGSMIAAEFNDPQTGKPSAAIAQKIQQRALAQGLLLLTCGAYG
                     NVIRFLYPLTIPDVQFDAAMKILQDALSD"
     gene            complement(63216..64496)
                     /gene="puuB"
                     /locus_tag="ACHY1N_001008"
     CDS             complement(63216..64496)
                     /gene="puuB"
                     /locus_tag="ACHY1N_001008"
                     /EC_number="1.4.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylputrescine oxidase"
                     /protein_id="HFS4043350.1"
                     /translation="MTEHTSSYYAASANKYAPFDTLNESISCDVCVVGGGYTGLSSAL
                     HLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRDIDVIEKSYGMDTARMLGSMMFE
                     GGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYGNKQLELLDANAI
                     RREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQIQHTTPAVV
                     RTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGTQVITTERLSEDLARSLIPKNY
                     CVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLVVPKLLKTFPQLKGVKIDY
                     RWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHLAGRLIAELLRGDAERFDAF
                     ANLPHYPFPGGRTLRVPFTAMGAAYYSLRDRLGV"
     gene            complement(64498..65985)
                     /gene="puuC"
                     /locus_tag="ACHY1N_001009"
     CDS             complement(64498..65985)
                     /gene="puuC"
                     /locus_tag="ACHY1N_001009"
                     /EC_number="1.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase PuuC"
                     /protein_id="HFS4043351.1"
                     /translation="MNFHHLAYWQDKALSLAIENRLFINGEYTAAAENETFETVDPVT
                     QAPLAKIARGKSVDIDRAVSAARGVFERGDWSLSSPAKRKAVLNKLADLMEAHAEELA
                     LLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVYGEVATTSSHELAMIVREPVGV
                     IAAIVPWNFPLLLTCWKLGPALAAGNSVILKPSEKSPLSAIRLAGLAKEAGLPDGVLN
                     VVTGFGHEAGQALSRHNDIDAIAFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSANLV
                     FADCPDLQKAASATAAGIFYNQGQVCIAGTRLLLEESIADEFLALLKQQAQNWQPGHP
                     LDPATTMGTLIDCAHADSVHSFIREGESKGQLLLDGRNAELAAAIGPTIFVDVDPNAS
                     LSREEIFGPVLVVTRFTSEDQALQLANDSQYGLGAAVWTRDLSRAHRMSRRLKAGSVF
                     VNNYNDGDMTVPFGGYKQSGNGRDKSLHALEKFTELKTIWISLEA"
     gene            complement(66260..66817)
                     /gene="puuR"
                     /locus_tag="ACHY1N_001010"
     CDS             complement(66260..66817)
                     /gene="puuR"
                     /locus_tag="ACHY1N_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator PuuR"
                     /protein_id="HFS4043352.1"
                     /translation="MSDEGLAPGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDK
                     VSPAISTLQKLLKVYGLSLSEFFSEPEKPDEPQVVINQDDLIEMGSQGVSMKLVHNGN
                     PNRTLAMIFETYQPGTTTGERIKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINT
                     GIPHSFSNTSAGICRIISAHTPTTF"
     gene            complement(66844..67608)
                     /gene="puuD"
                     /locus_tag="ACHY1N_001011"
     CDS             complement(66844..67608)
                     /gene="puuD"
                     /locus_tag="ACHY1N_001011"
                     /EC_number="3.5.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415814.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase"
                     /protein_id="HFS4043353.1"
                     /translation="MENIMNNPVIGVVMCRNRLKDHATQTLQEKYLNAIIHAGGLPIA
                     LPHALAEPSLLEQLLPKLDGIYLPGSPSNVQPHLYGENGDEPDADPGRDLLSMALINA
                     ALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVQ
                     VEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALG
                     VQWHPEWNSSEYALSRILFEGFITACQHHIAEKQRL"
     gene            67820..69238
                     /gene="puuA"
                     /locus_tag="ACHY1N_001012"
     CDS             67820..69238
                     /gene="puuA"
                     /locus_tag="ACHY1N_001012"
                     /EC_number="6.3.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-putrescine ligase"
                     /protein_id="HFS4043354.1"
                     /translation="METNIVEVENFVQQSEERRGSAFTQEVKRYLERYPNTQYVDVLL
                     TDLNGCFRGKRIPVSSLKKLEKGCYFPASVFAMDILGNVVEEAGLGQEMGEPDRTCVP
                     VLGSLTPSAADPEFIGQMLLTMVDEDGAPFDVEPRNVLNRLWQQLRQRGLFPVVAVEL
                     EFYLLDRQRDAEGYLQPPCAPGTDDRNTQSQVYSVDNLNHFADVLNDIDELAQLQLIP
                     ADGAVAEASPGQFEINLYHTDNVLEACDDALALKRLVRLMAEKHKMHATFMAKPYEEH
                     AGSGMHIHISMQNNRGENVLSDTEGEDSPLLKKMLAGMIDLMPSSMALLAPNVNSYRR
                     FQPGMYVPTQASWGHNNRTVALRIPCGDRHNHRVEYRVAGADANPYLVMAAIFAGILH
                     GLDNELPLQEEVEGNGLEQEGLPFPIRQSDALGEFIENDHLRRYLGERFCHVYHACKN
                     DELLQFERLITETEIEWMLKNA"
     gene            69387..69551
                     /locus_tag="ACHY1N_001013"
     CDS             69387..69551
                     /locus_tag="ACHY1N_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043355.1"
                     /translation="MPMIKSPHGEGGCVCAPPATDWTPPPLLPLLNRFDFRSTRPQTL
                     LRRGGSNYGY"
     gene            69541..70926
                     /gene="puuP"
                     /locus_tag="ACHY1N_001014"
     CDS             69541..70926
                     /gene="puuP"
                     /locus_tag="ACHY1N_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707205.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PuuP"
                     /protein_id="HFS4043356.1"
                     /translation="MAINSPLNIAAQPGKTRLRKSLKLWQVVMMGLAYLTPMTVFDTF
                     GIVSGISDGHVPASYLLALAGVLFTAISYGKLVRQFPEAGSAYTYAQKSINPHVGFMV
                     GWSSLLDYLFLPMINVLLAKIYLSALFPEVPPWVWVVTFVAILTAANLKSVNLVANFN
                     TLFVLVQISIMVVFIFLVVQGLHKGEGVGTVWSLQPFISENAHLIPIITGATIVCFSF
                     LGFDAVTTLSEETPDAARVIPKAIFLTAVYGGVIFIAASFFMQLFFPDISRFKDPDAA
                     LPEIALYVGGKLFQSIFLCTTFVNTLASGLASHASVSRLLYVMGRDNVFPERVFGYVH
                     PKWRTPALNVIMVGIVALSALFFDLVTATALINFGALVAFTFVNLSVFNHFWRRKGMN
                     KSWKDHFHYLLMPLVGALTVGVLWVNLESTSLTLGLVWASLGGAYLWYLIRRYRKVPL
                     YEGDRTPVSET"
     gene            71060..71305
                     /gene="ymjA"
                     /locus_tag="ACHY1N_001015"
     CDS             71060..71305
                     /gene="ymjA"
                     /locus_tag="ACHY1N_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmjA family protein"
                     /protein_id="HFS4043357.1"
                     /translation="MNHDIPLKYFDIADEYATECAEPVAEAERTPLAHYFQLLLTRLM
                     NNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGNE"
     gene            71618..73261
                     /gene="sapA"
                     /locus_tag="ACHY1N_001016"
     CDS             71618..73261
                     /gene="sapA"
                     /locus_tag="ACHY1N_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein SapA"
                     /protein_id="HFS4043358.1"
                     /translation="MRQVLSSLLVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQV
                     NTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWEVLDNGATYRFHLRR
                     DVPFQKTDWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSV
                     RKLDNHTVEFRLAQPDASFLWHLATHYASVMSAEYARKLEKEDRQEQLDRQPVGTGPY
                     QLSEYRAGQFIRLQRHDDFWRGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAAS
                     QLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLMQSIYYG
                     TAETAASILPRASWAYDNEAKITEYNPAKSREQLKALGLENLTLKLWVPTRSQAWNPS
                     PLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRP
                     LLSCAAIHSQTNLAHWCDPKFDSVLRKALSSQQLAARIEAYDEAQSILAQELPILPLA
                     SSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP"
     gene            73258..74223
                     /gene="sapB"
                     /locus_tag="ACHY1N_001017"
     CDS             73258..74223
                     /gene="sapB"
                     /locus_tag="ACHY1N_001017"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine export ABC transporter permease SapB"
                     /protein_id="HFS4043359.1"
                     /translation="MIIFTLRRILLLIVTLFLLTFVGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLIHWDFGVSSINGQPIAEQLKEVFPATMELCILAFGFALIVGIPVGMIAGIT
                     RHKWQDNLINAIALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKPITGFA
                     LIDAWLSDSPWRDEMIMSAIRHMILPVITLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAI
                     RQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEWYALR"
     gene            74210..75100
                     /gene="sapC"
                     /locus_tag="ACHY1N_001018"
     CDS             74210..75100
                     /gene="sapC"
                     /locus_tag="ACHY1N_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HFS4043360.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCI
                     FGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
                     AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMIS
                     VLLVNLLGDGVRRAIIAGVE"
     gene            75100..76092
                     /gene="sapD"
                     /locus_tag="ACHY1N_001019"
     CDS             75100..76092
                     /gene="sapD"
                     /locus_tag="ACHY1N_001019"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HFS4043361.1"
                     /translation="MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGS
                     GKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE"
     gene            76094..76900
                     /gene="sapF"
                     /locus_tag="ACHY1N_001020"
     CDS             76094..76900
                     /gene="sapF"
                     /locus_tag="ACHY1N_001020"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HFS4043362.1"
                     /translation="MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTDLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDR"
     gene            76968..77321
                     /gene="ycjD"
                     /locus_tag="ACHY1N_001021"
     CDS             76968..77321
                     /gene="ycjD"
                     /locus_tag="ACHY1N_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF559 domain-containing protein"
                     /protein_id="HFS4043363.1"
                     /translation="MMDKIKSNARDLRRNLTLQERKLWRYLRSRRFGDFKFRRQHPVG
                     SYILDFACCSARVVVELDGGQHDLAVAYDTRRTSWLESQNWTVLRFWHNEIDCNEEAV
                     LEIILQELNRRSPSP"
     gene            77689..78477
                     /gene="fabI"
                     /locus_tag="ACHY1N_001022"
     CDS             77689..78477
                     /gene="fabI"
                     /locus_tag="ACHY1N_001022"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFS4043364.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            78622..79749
                     /gene="yciW"
                     /locus_tag="ACHY1N_001023"
     CDS             78622..79749
                     /gene="yciW"
                     /locus_tag="ACHY1N_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309887.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CMD domain-containing protein"
                     /protein_id="HFS4043365.1"
                     /translation="MEQRHITGKSHWYHETQSSTAEYDVLPLVPEAAKVSDPFLLDVI
                     LDEETLAPFLSWLVPARVLAVELFPDQLTVTRSQTFTAYERLSTALTVAQVCGVQRLC
                     NYYSARLTPLPGPDSSRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTAGDC
                     VIINQIIGFIGFQARTIATFQAYLGHPVRWLPGLEIQNYADASLFADESIRWRSSYEV
                     EKLPEEYTKSSTAELCQLAETLSLHPISLSLLERLLNSTRVNTQPDNKLAALLCARIN
                     GSPACFAACMDSSNEYKKISPLLRKGENEINQWADRHSVEHATVQAIQWLTRAPDRFS
                     AAQFSPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY"
     gene            79817..81751
                     /gene="rnb"
                     /locus_tag="ACHY1N_001024"
     CDS             79817..81751
                     /gene="rnb"
                     /locus_tag="ACHY1N_001024"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008859 - exoribonuclease II activity
                     [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HFS4043366.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPD
                     HPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP
                     WWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALP
                     DDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIA
                     EQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA
                     MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFC
                     KLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAA
                     EIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVI
                     DVTIAEVRMETRSIIARPVA"
     gene            complement(81829..81933)
                     /locus_tag="ACHY1N_001025"
     CDS             complement(81829..81933)
                     /locus_tag="ACHY1N_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043367.1"
                     /translation="MTYMKLTAAKRIVFFIYLFVIQFWKNASFQTKVS"
     gene            81987..83972
                     /gene="pdeR"
                     /locus_tag="ACHY1N_001026"
     CDS             81987..83972
                     /gene="pdeR"
                     /locus_tag="ACHY1N_001026"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HFS4043368.1"
                     /translation="MKTVRESTTLYNFLGSHNPYWRLTESSDVLRFSTTETTEPDRTL
                     QLSAEQAARIREMTVITSSLMMSLTVDESDLSVHLVGRKINKREWAGNASAWHDTPAV
                     ARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLKEHDVIGQSVFKLF
                     MSRREAAASRRNNRVFFRSGNAYEVELWIPKCKGQRLFLFRNKFVHSGSGKNEIFLIC
                     SGTDITEERRAQERLRILANTDSITGLPNRNAMQDLIDHAINHADNNKVGVVYLDLDN
                     FKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMA
                     SRILTRLRLPFRIGLIEVYTSCSVGIALSPEHGSDSTAIIRHADTAMYTAKEGGRGQF
                     CVFTPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPER
                     GLIPPLDFISYAEESGLIVPLGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQT
                     IFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSQLGAQVHLDDFGTGY
                     SSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKE
                     DAFLTKNGINERQGFLFAKPMPAVAFERWYKRYLKRA"
     gene            complement(83954..84082)
                     /gene="ymiD"
                     /locus_tag="ACHY1N_001027"
     CDS             complement(83954..84082)
                     /gene="ymiD"
                     /locus_tag="ACHY1N_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmiD"
                     /protein_id="HFS4043369.1"
                     /translation="MQKLPLKEKCLTATANYHPGIRYIMTGYSAKYIYSSTYARFR"
     gene            84119..84292
                     /gene="yciZ"
                     /locus_tag="ACHY1N_001028"
     CDS             84119..84292
                     /gene="yciZ"
                     /locus_tag="ACHY1N_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YciZ"
                     /protein_id="HFS4043370.1"
                     /translation="MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVA
                     ESTPDIPKAPWEI"
     gene            84382..85131
                     /gene="yciT"
                     /locus_tag="ACHY1N_001029"
     CDS             84382..85131
                     /gene="yciT"
                     /locus_tag="ACHY1N_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YciT"
                     /protein_id="HFS4043371.1"
                     /translation="MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKL
                     SYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLA
                     RTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
                     SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVE
                     RFNRVITDSKIRASDLMHLEHSKLTVHVVDI"
     gene            85400..85618
                     /gene="osmB"
                     /locus_tag="ACHY1N_001030"
     CDS             85400..85618
                     /gene="osmB"
                     /locus_tag="ACHY1N_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmB"
                     /protein_id="HFS4043372.1"
                     /translation="MFVTSKKMTAAVLAITLAMSLSACSNWSKRDRNTAIGAGAGALG
                     GAVLTDGSTLGTLGGAAVGGVIGHQVGK"
     gene            complement(85744..86070)
                     /gene="yciH"
                     /locus_tag="ACHY1N_001031"
     CDS             complement(85744..86070)
                     /gene="yciH"
                     /locus_tag="ACHY1N_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HFS4043373.1"
                     /translation="MSDSNSRLVYSTETGRIDEPKAAPVRPKGDGVVRIQRQTSGRKG
                     KGVCLITGVDLDDAELTKLAAELKKKCGCGGAVKDGVIEIQGDKRDLLKSLLEAKGMK
                     VKLAGG"
     gene            complement(86070..86807)
                     /gene="pyrF"
                     /locus_tag="ACHY1N_001032"
     CDS             complement(86070..86807)
                     /gene="pyrF"
                     /locus_tag="ACHY1N_001032"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFS4043374.1"
                     /translation="MTLTASSSSRAVTNSPVVVALDYHNRDDALSFVDKIDPRDCRLK
                     VGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASG
                     GARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLVDLGMTLSPADYAERLAALTQK
                     CSLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYM
                     VIGRPVTQSVDPAQTLKAINASLQRSA"
     gene            complement(87000..88169)
                     /gene="lapB"
                     /locus_tag="ACHY1N_001033"
     CDS             complement(87000..88169)
                     /gene="lapB"
                     /locus_tag="ACHY1N_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0008653 - lipopolysaccharide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HFS4043375.1"
                     /translation="MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVN
                     FLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT
                     YEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKA
                     IDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSI
                     MMGRVFMAKGEYAKAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAV
                     EENTGADAELMLADIIEARDGSEAAQIYITRQLQRHPTMRVFHKLMDYHLNEAEEGRA
                     KESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL"
     gene            complement(88176..88484)
                     /gene="lapA"
                     /locus_tag="ACHY1N_001034"
     CDS             complement(88176..88484)
                     /gene="lapA"
                     /locus_tag="ACHY1N_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA"
                     /protein_id="HFS4043376.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVVPHSSAAKE
                     "
     gene            complement(88633..89397)
                     /gene="pgpB"
                     /locus_tag="ACHY1N_001035"
     CDS             complement(88633..89397)
                     /gene="pgpB"
                     /locus_tag="ACHY1N_001035"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004609 - phosphatidylserine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HFS4043377.1"
                     /translation="MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWV
                     TETVTQPWGVITHLILFGWFLWCLRFRIKAAFVLFAILAAAILVGQGVKSWIKDKVQE
                     PRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWALVAVATWLAQRICGPLTPPAEENREIAQREQES"
     gene            89567..90157
                     /gene="ribA"
                     /locus_tag="ACHY1N_001036"
     CDS             89567..90157
                     /gene="ribA"
                     /locus_tag="ACHY1N_001036"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HFS4043378.1"
                     /translation="MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTE
                     AGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK"
     gene            complement(90221..>92192)
                     /gene="acnA"
                     /locus_tag="ACHY1N_001037"
     CDS             complement(90221..>92192)
                     /gene="acnA"
                     /locus_tag="ACHY1N_001037"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HFS4043379.1"
                     /translation="AMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLRKHG
                     VVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSEDQV
                     ELVEKYAKAQGMWRNPGDEPIFTSTLELDMNDVEASLAGPKRPQDRVALPDVPKAFAA
                     SNELEVNATHKNRQPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLLAKK
                     AVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNSGPL
                     PDPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNINLA
                     AEPIGHDRKGDPVYLKDIWPSAQEIARAVEQVSTEMFRKEYAEVFEGTAEWKEINVTR
                     SDTYGWQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGSIKP
                     DSPAGRYLQGRGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTRHLP
                     DSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESFERI
                     HRSNLIGMGILPLEFPQGVTRKTLGLTGEEKIDIGDLQNLQPGATVPVTLTRADGSQE
                     VVPCRCRIDTATELTYYQNDGILHYVIRNMLK"
BASE COUNT        22986 a        23698 c        22365 g        23143 t
ORIGIN      
        1 gacctggcga ttatgcgtcg ctcgctctca ccactgagct aaagggccgg gagcagaata
       61 ataacggtcc gtaattaatt ccgcaataaa aaacccgctc aatggcgggt tctggtaaag
      121 ttcatgcgct tggttcgcct cgcgatacag ctttgcgaag cgtaccggaa ttgaagcagt
      181 ttatgcgtaa aaaatcaagc tattttttga gcaaatgatt ctcgcatggg aatatatagg
      241 acatactcag caactgccaa ccaattagca attcgctttt cgcatgtgct aaaacaccac
      301 tctgggtact gttcgtttaa taactcggcc atccttctct tactcatccc tcgccccaca
      361 taacgctgac tcaggacatt tagtagtcct ggatgatccg ccagaacttc acctataaca
      421 ctatcaattt ttagtgcctc tgcatcagtg cagtgagtta accagctttt ttgctttcct
      481 tcgatcatct cacgcaaaaa tgcttccaac tctggtttat caattcccgc ttttttcaat
      541 ctgcgcaggg cttcattgat ggctgttttt gtcaattttt tggatgtcag caactgatta
      601 aacatattcc ctgacctgcc gccaccaatg tacgaccagc gcccccacat acgcagtttc
      661 ccctgtatcc agatgctttc caacgtattg agtcgaagat gttctccgct ttttccggta
      721 tttgttgggt aaatcataga atgcctttct ccctccagat ttcctgtgtg cggaaaacgc
      781 cctccgcgtg catcaggcgc aattcttctt tggtgtaatc gctggttttt acccgcccgt
      841 cgattaaatc gtggcacgag ctacaggcaa ttgccgcctg catatcgtgt ggttttgtcg
      901 ctgttccaca cgtccccgcc agcctgtaat gcgccagcac ggacgtttcg ggattgtgat
      961 tgcagtagcc aggaattctg actgtacaca tctgaccttt tgccgcttta cgtaaatcca
     1021 ccattacgca aactccagta gctgcgcggc cacattttcg acttgttccg gagaggaaaa
     1081 tttacggaac aggatccagt tccacagtac attcagcaca gatttataaa cctgctgaaa
     1141 ctcggtttcg tccatattcg caaacgcgat ggatttcgcc ctgcgcccac ggctaccgtc
     1201 cggataaaaa tgctcggtgt aaaatccggc ctgaatggtt acccactcgc ggaaagcctc
     1261 aaacgacttt agcaatgccg tatcccgggt tctgcgtgtc gcaacggtat tcagatattg
     1321 ctctgcggca tcactcaggg ctggagtatg ttcccgacct actgattcgc acaggaaatc
     1381 aacgaaaccg gacaccagtt ctcgttcgcg aggcgtgatc gccccaccgt tcggagtcca
     1441 gtaatcgaat cccagttgca ggagtttgaa aaaacgcttg tggaatgcgt agttacgcac
     1501 acgcttaaag tctgcgtgta tccactcacc gattttgatt tgatgcaaaa aatcgcaact
     1561 ctccggcgtc gccgggagaa gtaatccgga agaggtttgt ttgaccagtt gtatatgcgc
     1621 catcgtagtt ctccgctggc gcagtagaat gggtgttcag cccgttatgt agtataccag
     1681 aattaatgcc aatactaaca ggatgctctg actcgcaatt catccagcag tttatcattt
     1741 cccataatgt cacttaccct catcggtaaa aaaattgcct ttcgaccatt acgatacatc
     1801 attgattttg gggtttcagg gaagtaatcc atttcgacta taactgacag gtcatcacga
     1861 cgtatgactg cgtatttgca actaaatagt ttctttattt tttccacgat gcctccgagt
     1921 ttataagtac aaacggttat atccacatag agacaaaaat attaatctga aaaatattta
     1981 tttcacgccg tatatttgat tatttaatgt gcaggtacaa tgacttttat tttttgttgt
     2041 gtatataatc aaatatatgg ttatttttca ccctgcgcat tcagcgcgca acaaaaaacc
     2101 cgccgaagcg ggttaagtgc gggtgcgttg aggatgcctg acacatcaga ggtggcgagg
     2161 gatttctccc ccgccaggtc tcttactcct caggttcgta agctgtgaag acagcgacct
     2221 ccgtctggcc ggttcggatt cgtacctcgc agaggtcttt cctcgttacc agtgccgtca
     2281 ctatgacggt taaacagatg acgatcaggg cgactaacat cgccttttgc tgcttcatag
     2341 cctgcttctc cttgcctttc ggcacgtaag aggctaacct acgtttgtga agcatagatt
     2401 gggcctcaga ttaatgttaa gcgtcttgca ggacgcgtaa tgttaactgg ggcttttctc
     2461 tatctgcctt ttggtgttca tgcctgaggc agatagcctc aagcacccat tatgatttta
     2521 accaaagtct ttgtatctat aaagaggcac aatattactc gatatatcat catgtgtgcg
     2581 ccttattcca aacattttgg aaacaaagcg ttccctcact cccgacatat ccagtatctg
     2641 cttccaagaa gatatatcca gcaattcaac tgcacaggaa agtaagcgag gtttttcctc
     2701 agggattaac tcatccccca tctctccttt aatcgtccct cttttattta gatggataaa
     2761 tcccgttctc atttgttgtg gcgtaatcag ccccaaaacc gtagcacgat aaatacacat
     2821 gcgaagactg attttccatc gttctttgaa attaattagt gcattccagt caagatgcga
     2881 tcctcgcatt ttaggaaatt cattaacgaa cgaaactcta ggtacaagga atgcgctcga
     2941 aaaataatcc gcatgatgtt ctgtaatttt atcccctgtt ataatccctt catgcaaaac
     3001 aagatgcccc agttcatgac cgagatctga gcgaaatcga cacacactct ttttcgcgga
     3061 atttctaatt atcaatgggc gtttactatt aatagtaaac gcatcaatac gatcatccac
     3121 gccagataca tgagcaacaa caaccccaat actttccacg aaattaacca ttgaagatat
     3181 cggtcccagc cccaaacccc aataccttct acaggcctcg gcaattcttt caatatcttc
     3241 atcggagttc aaaggtaatc cggacgtatc aggaaagttc aattctggaa gaactatttc
     3301 tgtttccaaa cactttacaa actgctccaa aatttcagct cgagccagaa tactattagt
     3361 taaggactgc gtccttgatc tcttgcttct gaaatggcag ttctcgctgt ctaatggtga
     3421 tttccttcca gtgaagaaaa acgactcttt aacatccaga taatctgcaa gagctgtcaa
     3481 catctgagat gaagggggat aaccacgctc taacttgttt ataaattgcc gagtcacccc
     3541 caaagcagta gcaagctctt cgcccgtaac ccctttagcc tgacgagcta attttaagca
     3601 gtcaccacga taattaccta tagaatcaaa tagttccata tttatcacta tctgcttttt
     3661 tcgcattctt aacacgccgc tgcaaattca gcggtggtgt ttccacggcc tctggcaata
     3721 cgtcagtatt agctgcttgt actggagcat ggactttaga caccaattcg tatctactca
     3781 ctacattatt tgatgaatca aaacctatca gggctaaaag ccacgttgga ggttcaatat
     3841 cttcatcttt tttatttgca gatggtaatt tttcagccag aacacgccat gtaacatcat
     3901 gttcaaaatt aacatcatct tcaaaaagag ataactgacg acactcaaca tcatttttac
     3961 ataagcgatg tttctttttt ggtgaatcca gtttatcggt cacaaactgt aacggcaccc
     4021 tgttcagggt aaacacaaaa ttcagaggtg ttgaaagaat cgccactcct ttgagttttt
     4081 tatgattttt tacaagaaag ttttttatcc atccataggc cctacatcca ttaatccagt
     4141 tatcatcata ctcatggcga tggaaccata attcgccaag tacgttagca aattgctgaa
     4201 gaagattgat aacagatttt tcatccaaac aaggattgat ttcaaaacac ggttggagat
     4261 tctgttcaga cggcataagg tatccctctc tcttaaaact ccgctcatct ttacgcaaaa
     4321 ttttattttt gtaaacctaa tctttagggg atttcacgaa ttcgtcaacc agtcgaacaa
     4381 actttaacca caatacatat ttatctacat tgatatgtgt atcgctaaca ctattgtggg
     4441 cattcagcta gtattaccaa gccttcaggt gcgcgaagtt gttccgcaca gtgcagcagc
     4501 gcatcagtcg cttccttaag cgtcacagtg tcgccatcac ccagtcctgc aatttttgcg
     4561 tgcctgacaa acgccgcgca aaggtcgtta aacgcccctg cccgcacatc cgccaggaaa
     4621 gcgttggcag cagccaaatc ctggtagtca atcccgctca ctgtgccacc tcctgaaaat
     4681 taccctgata aaacgccagt gcgcgctgca taacttcgct cttccggcac tcgctacaga
     4741 ttatgttctg acgcctgtcg tagcggcgta tttctccgtc tggtaatgac cagataaggt
     4801 ccggatcatc cacagatgtt ttcttcagat ttgcccttga gagttttttg cgggcgtttt
     4861 gccagtcctt acgcgcctgt tcagacggga ataacccgta accagagttg tatacatcgc
     4921 cactggcaac cagctctctg gcgagaacac tcatcagata tcttgtcgca cctgttttct
     4981 cttccagttg ccgtaacgtc tcgcggccgc tcagacgtac aagttcaaca acctgccctt
     5041 taattttttc ccgctcttct ggtgtaaata cttttgccat gggcgcctcc ggcaatcact
     5101 tttccgatgc aacacggcgg gaaaaatcag taatctgtcg aacaatatcc cgatgcttgt
     5161 tcagctcccg cagcgcggcg cagacacgct cccacttctg gacatgattt ttcgcccgac
     5221 gcagttcacg gtttgccata tgcagcgatg acaaaatcaa atcatcagat cgcgttgcag
     5281 taaacgatgg cagcgactgc acaatgtccg ccacagtttc tgttttaata tcttcctgtg
     5341 ttgcagcctc ctgtactggt aacgcaacac atgcaggctg aggaaaggct ttaccatcag
     5401 tttccgctac cgatgctgct ttcggctctg ctggtaaatt atcgcccggt atgcagtaac
     5461 gaaatttacc gttctggttt acgcgaatca ggcgtccttt gctgattgcc attgccagcg
     5521 ttgaagcaac tttgcgggat gttgtaccga acagcgtagc cagttcatcc gccgtttgtg
     5581 gtccgcgttg ttcaatcgtc gcggttaaat cgcactctga gattttcgct actgttgccg
     5641 tggtggtttc ttccggcagt tctgcctgca ttggctgttc ctgctgaacg ttgttatcgg
     5701 ccacacgcca ggtgtatacg cttttatcaa cgaatccagc ctttttcagt tcccaaagct
     5761 cgttcagcac ttcttcacga ctgatatcaa gtcgcgcagc cagttctacc gacgtggctt
     5821 ttcccattgc tttcagtgca ccaaaaacgg tttccattaa aatttcctcc cggtaaaaat
     5881 cacttcgcaa ttcctggctg gacgacattc ggacgccagc tctcccagtt aaaattcacc
     5941 catcgcccgc cgttcatggt catgcgatcc ataatcctct cgccgagcaa tgttttcatg
     6001 gcctcatagt tcaggtttgt cagcatcccc acgctgcgca tcgacgctgt ccggcgatca
     6061 acaatctggt gcagcaccac ctgctcgttt tttgtctcgc gctgaatgcc aatttcatca
     6121 agaaccagca gatccacttc gcacagttcc cgcaaaaatt tttcgcctga ctgcccgtcg
     6181 tcatagctgg cgtgcagggc gctcataaca tcagccacgg taaccacaat cactgtctga
     6241 ccgtctttca gcaggcgatt cccgatagct gccgctaagt gattcttccc ggtaccaggt
     6301 tttccgctga acgcaaaatt tgtacacccg gtcatcagtt catcggcgat ggatttcgcc
     6361 tggcttaacg cgtatcgctg gccgtcgttc tgcacctggt aattcgcaaa cgagcattta
     6421 cggtgcaacg gctggatgcc tgagcgattc agaatttttt ccacccgcaa ctgacgattc
     6481 aggcggttga tctcctcgct acgtttctgg ccttcagcaa gttgccactc gcgccactcc
     6541 gcaaccgttc tgaatggggc ggttacatgt ggtggggcca gtctgcggat acgctccaga
     6601 acgcctcctg tcgcaatatt tttcatggtc tgttaccccc tgaagcctgg cgggatcgca
     6661 ctgtccggca acgagacggt gttaacctgt cggagcaacg tctcaggccg aacacctttc
     6721 ggcgcgaaca ggccctggta ttcattggcg atgctgtttc gaatcaccag ctcaggtgta
     6781 aaaccctgct gacggaattt ttccagttcc cgtatcgccc cgttagcgcc ctgctccgtt
     6841 cgaatcggtt ttcgcaatgc ctgtctgaac cggacccact catgccagag tgtttccggc
     6901 aaccaatcgg gcagctcaat agcctccggc tcgaattttt tagacgctcg tttttggcga
     6961 gggggattta gggggagatc agtatttaga tcttcctctt cctcttcctc tggtaacgct
     7021 ttttgatccg tttgtgtaac gccggcagcg ttaccttttc gtttcagttc acgtattttt
     7081 gtaactcgct cgtttgtaac cgcccgtttt ttagagcttt ttccgttatg gcgttcaaag
     7141 ttaggtagag aaagcccaac gtcattttcg accagccatc caacctgaat taacgcatca
     7201 gcaaaaccag ccataaaaga gatgcgatct attgcacttt ttgtaacgcc gcgagcgtta
     7261 caatctgcat taccgtctat catttgttga tccgcccatg cccagaagcg aataaccttc
     7321 cctaatgcgg catctggatc aatattcaga atctcagcaa gcctgaatat ttccggctta
     7381 tccggcgtaa taacctcgag ctttatccag tttgaagcca tttgttttca ccttgtaacg
     7441 ctcgcagcgt tacatttaac tgataccgaa caaaacaatc cggcacgatt aatttcaatc
     7501 aatgcactac gacagaatca ccgggcgacc caccaccgct gaaatgtgct ttccggtaaa
     7561 cggcctggac tgcatcatca tgcgcatcaa ttgccgtact caacgcttcc tgcgccgcca
     7621 gtaatgcacg gcgttccagg gtatcgaaga tgcagagtcg gtgacgcagc tcgcgcggaa
     7681 gaattgccag aaccgcaggg atcagtttct gaattttttc cctttgcgct ttcgtttcac
     7741 ctttcaacca acggtgatag atattctgct gattgttcca gtccttgcct ggtaccaggg
     7801 gcaattcgcc gcccccctgg cgcagatatt catcagtaat tgcgttagcg acccacgcct
     7861 gccctttttc ggctgccagg gctaacagca ctgattcgat gtgctcatgc ctgattttca
     7921 tgaatcaacc gctcctatgc tgttttcgct atgcttaccg tctgggggga atacatcgtc
     7981 aagtccacaa tgagcgccaa gccgattaag ggtagaaaca atttttctgc actcctctag
     8041 tccaggggta cgaaaatttg cttcgtaatt tgccagtcgg ctttgtatcc accctaactg
     8101 aacagcaagt tgtctttgag acagcccaag ctgttttcga tatgttgaaa ttttgttcat
     8161 tgaaaacctc cgatgacaat tttaaacaca tcttgtgtta tatggtcaag ctgttttgtg
     8221 ttttgtgtaa atcacgattc gtgatacaag gatgcaatgg aaaaagaaaa cgaaaaaatt
     8281 gccgctagta ggctcaatga caaaattgca atgcgtctta aagagcgcag gcagaagctt
     8341 ggtttatctc aaggaaaact tgctgaaatc tgcggatgga cgcaatcgcg tataggtaac
     8401 tatgaggcgg gtagcagaaa tgttggagtg catgacgctg tcgtattggg aaaggcactt
     8461 ggcatatctc ctcctgagct cctctttgga gaacaggaat cttctgaatt gtggttaaat
     8521 gaatcccaac gaaaacttct tgagttgttt aaccagctac cgggctcaga acaacaacga
     8581 atgattgagc tatttgaagt ccggctaaaa gaaatcgatg agtatgtaga aaaatatttg
     8641 agaggcaggc ttaaagataa tcccccaccg gagtaatgat cttgctatca cagtaatatg
     8701 ccaatcagcc cgctatcagc gggctttttt tgtaccatca tcatatgaca cccaccacaa
     8761 aacacatttc gtgttgacac aagaaaacgc attgtgttta ataagcatat ccaaacaacg
     8821 ccccaccaga gaacggcagg acaatacctc gagttatcca gccactgaac agggctaagt
     8881 agccagcctg aggcatacga acatgacggc agttgttgat tgatacaaag cgcagtagat
     8941 aaaacgttcc gccacccggc gttaagggga aatgaggtca acatggatac tatcgatctt
     9001 ggcaacaacg aatctctggt atgtggcgtg tttcccaatc aggacggcac attcaccgcc
     9061 atgacgtata ccaaaagcaa atcgtttaaa accgaagctg gcgcacgtcg ctggcttgcc
     9121 aaaaatacca gctaaaccat ttattggatt aattcaatat tcttgctgta ggggtatagc
     9181 cgaggccacc aaagcccgga ggtggtgaaa taaaaccggg cacaacacga aggcgcattt
     9241 ccgatatcca taaagagtcg gtcttgtctg ttaaatttaa atggtgggag tgcgcctccg
     9301 gttgtaaata acgacattgc tgtgtgtagt cttggcggca tcagttctac tccgtggctg
     9361 ccctgccgcc cctttttaaa gtgaattttg tgatgcggtg aatgcggctg agcgcacgcg
     9421 gcacagttaa aagcatcagt gttatgggtg gattatccgg cgttaattgt taactggtta
     9481 acgtcacctg gaggcaccag gcaccgcatc aacaaagttc acttcagtga tgaaaggtga
     9541 gagaaaatgt tggatgtagc tattgaaaac cagaacgggt ggaattatag tgcacctgca
     9601 cctcataaaa cgggtgccgg gatttgcacc ccgatgatca ctagagcgca taaccgcgcc
     9661 aaagcggttt ttttatgcgt aaagcgcagc cacattcaga ttatggtggg gcgtatgggg
     9721 ccgttttcgg gcgggccgga ttctctagtg accggtagtg caaaccctgt acgtctcacc
     9781 acccatgaga tttgcacctc cggtggtgag tttaccaact tatcactaga ggctgccatc
     9841 atggctacta tccctaccct ttctcaccct gacgtaacca tcgaaaatgg tcgtgctgtc
     9901 actacgtctg ttgcagttgc agagtttttc cgcaagctgc ataaaaacgt cattcaaaaa
     9961 attgaagctc tggaatgttc ctcagaattc actgagctta attttaagcc aagtgaatac
    10021 accgactcaa ccgggcgcaa actcccaatg taccaaatca ccaaaaacgg cttcgttttc
    10081 ctggtgatgg gtttcactgg caaaaaagcc gctgcattca aagaggccta catcgctgag
    10141 ttcgaccgca tggaagcaga gctacgccag aataatacca ctcccacaaa caaaatcatt
    10201 ccgggcgatg ggcgcactct ggttgttcgc ttcgacaaat tcggcaacgt cgaattcact
    10261 gaaaccgttc ctgatggcgc tctcgtctgt accctggaca ctttccgcct ttatctggag
    10321 aaacagggct ggactcttgt aaaccgaagc gcaattaaaa atatgaccgt cgagcagttg
    10381 ctgagtatta aatagttttc tggaattttc ttaatacgag aaatttatta aggagataat
    10441 tatgattgct catcacttcg gaactgatga aataccacgt cagtgtgtga ctcctggcga
    10501 ttatgttctt catgaaggtc ggacatatat cgcctcggca aacaatatta aaaagcgaaa
    10561 actttatatt cgtagcctga ctacaaaaac atgcatttct gactgcatga ttaaagtctt
    10621 cctcggtcgt gatggtttac ctgtaaaggc ggagtcatgg tgatgactaa gaaaataaaa
    10681 tgtgcttacc acctttgcaa taaaggaatt gaagaaagca aaagtattaa aagaccactt
    10741 catttcatgc gtggagttat cccaacgacg gaaatgaaaa aatattgtag tgaaaattgt
    10801 gccgaaaaag accagatggc acacgaactt taactaactg actattcgaa actgaattta
    10861 tgccagcaat ggcaggggtt cgctcaacct taaaatagtt atgaggttta tcaatgagta
    10921 ctgataaaga aaattacgct ctgtattgcg acgcgaaaaa tgataaaacc agaaaacgcc
    10981 tcggcatcaa aggcggcttt ttctggacag aggcaaaaaa actttctgtt gcggtttcac
    11041 gctgcattgc tgcaatggac gatgccggat ttgacgaaga ggattttaaa aaacccatcc
    11101 gcgtccattt acccgttgtg aatgaccttc caccggaagg tgtgtttgat actgaattct
    11161 gcaaccgata cgaaaaaggc ggagaagatg gtatcacaat gatacttatc gcgccctctg
    11221 ttccggacaa accagccagt actgacaata ccaacgtcaa cggcgaagac atggctaaga
    11281 ttgaggagaa tatgcttctt ccggtttcag gtcagattct gcctgttcgc tggctggcgc
    11341 aacacaacag cgaaaaaccg ctcacgcacg tttcactgga caaactgcgc gcattacata
    11401 acgcacagga tgaaaaactt cccgccgtta ccgcgctggc catctcaaat aaagcagtgc
    11461 aactcgaacc gctggagatt cgggatttgt acaaactggt gcgagacact gacaaagttt
    11521 tccccgcccc cgtaaattcg gacctgggac tgatgacctc ttttatcgaa gcatacctgg
    11581 gcgctgacta caccgatcgc ggtctgctta caaaagagtg gatgaaagga aatcgtgttt
    11641 cacgcatcag ccgcacgcca tccggcgcta acgctggcgg cggaaatatt accgatcgtg
    11701 gtgaaggatt caaacatgat aagacatcac tcgcacgaga tgtagccacc ggcgttctgg
    11761 cccgttcaat ggatgtggat atttataacc ttcatccggc acacgctaaa cgtgtcgagg
    11821 aaattatcgc tgaaaataaa ccgccctttt ctgttttccg cgacaaattc atcaccatgc
    11881 ctggcgggct ggattattcc cgcgccatcg tggttgcgtc cgtaaaagaa gcaccaattg
    11941 ggatcgaggt tatccctgcg catgtcactg aatatctgaa caaggtgctg attgaaaccg
    12001 atcatgccaa ccctgatccg gaaatcgtgg atattgcctg cggtcgttcc tctgccccga
    12061 tgccgcagcg tgtaacagaa gaaggaaaac acgatggtga agaaaaaccg caaccatctt
    12121 gcgcaatggc agataaacag gcaacggctg aaacagtgga accggatgca actgaacatc
    12181 atcaggacac gcagccgctg gatgctcagt cacaggtaaa ttctgttgat gcgaaatatc
    12241 agaaactgcg ggcagaactc catgaagccc ggaaaaccat tccgcccaaa aatcctgtcg
    12301 atgccgacaa attgctggct gcctctcgcg gagaatttgt tgaagggatt agcgacccga
    12361 atgatccgaa atggattaag gggatccaga cccgcgattc tgtgtaccag aatcagccag
    12421 aaacggaaca gaacgaccag aaagcggaac agaacagccc aaatacgcaa caaaacgagc
    12481 cagaaacgaa acaacctgaa ccagtagtgc aacaggaacc ggaaaagatc tgcaccgcct
    12541 gcggccagag gagtggcggc aactgccctg attgtggcgc ggtgatgggc gacgcaacat
    12601 accaggaaac attcgatgaa gagaatcagg ttgaagctaa ggaaaatgat ccggaggaaa
    12661 tggaaggcgc tgaacatccg cacaatgaga atgctggcag cgatccgcat cgcgattgca
    12721 gtgatgaaac tggcgaagtc gcagatcccg taatcgtaga agacatagag ccaggtattt
    12781 attacggaat ttcgaatgag aattaccacg taggtcccgg tgtcagtaag tctcagctcg
    12841 atgacattgc tgatactccg gcactgtatt tgtggcgtaa aaatgccccc gtggacaaca
    12901 caaagacaaa aacgctcgat ttaggaaccg ctttccactg ccgggtactt gaaccggaag
    12961 aattcagtaa ccgctttatc gtagcacctg aatttaaccg ccgtacaaac gccggaaaag
    13021 aagaagagaa agcgtttctg atggaatgcg caagcacagg aaaaacggtt atcactgcgg
    13081 aagaaggtct gaaaattgaa ctcatgtatc aaagcgttat ggctttgccg ctggggcaat
    13141 ggcttgttga aagcgccgga cacgctgaat catcaattta ctgggaagat cctgaaacag
    13201 gaattttgtg tcggtgccgt ccggacaaaa ttatccctga atttcactgg atcatggacg
    13261 tgaaaactac ggcggatatt caacgattca aaaccgctta ttacgactac cgctatcacg
    13321 ttcaggatgc attctacagt gacggttatg aagcacagtt tggagtgcag ccaactttcg
    13381 tttttctggt tgccagcaca actattgaat gcggacgtta tccggttgaa attttcatga
    13441 tgggcgaaga agcaaaactg gcaggtcagc tggaatatca ccgcaatctg cgaaccctgg
    13501 ctgactgcct caataccaat gaatggccag ctattaagac gttatcactg ccccgctggg
    13561 ctaaggaata tgcaaatgac taagcaacca ccaatcgcaa aagccgatct gcaaaaaact
    13621 cagggaaacc gtgcaccagc agcaattaaa aataacgacg tgattagttt tattaaccag
    13681 ccatcaatga aagagcaact ggcagcagct cttccacgcc atatgacggc tgaacgtatg
    13741 atccgtatcg ccaccacaga aattcgtaaa gttccggcgt taggaaactg tgacactatg
    13801 agttttgtca gtgcaatcgt acagtgttca cagctcgggc ttgagcccgg tagcgctctc
    13861 ggtcatgcat atttactgcc ttttggtaat aaaaacgaaa agagcggtaa aaaaaacgtt
    13921 cagctaatca ttggctatcg cggcatgatt gatctggctc gccgttctgg tcaaatcgcc
    13981 agcctgtcag cccgtgttgt ccgtgaaggt gacgagttta gcttcgaatt tggccttgat
    14041 gaaaagttaa tacaccgccc gggagaaaac gaagatgccc cggttaccca cgtctatgct
    14101 gtcgcaagac tgaaagacgg agggactcag tttgaagtta tgacgcgcaa acagattgaa
    14161 ctggtgcgca gccagagtaa ggctggtaat aacgggccat gggtaactca ctgggaagaa
    14221 atggcaaaaa aaacggctat tcgtcgcctg tttaaatacc tgcctgtctc aattgaaatc
    14281 cagcgtgcag tatcaatgga tgaaaaggaa ccactgacaa tcgatccggc agactcctct
    14341 gtattaaccg gggaatacag tgtgatcgat aattcagaag aataattcag cctggcggtg
    14401 taatgcaccg ccaacgcgag acagttttta tgacaaaaat tatgagatat gacgatgtta
    14461 aaccatgtcc gttttgtggt tgtccatctg ttacggtgaa agcaatttca ggatattacc
    14521 gggcaaaatg caacggatgc gaatcccgaa ctggctatgg tggaagtgaa aaagaagcac
    14581 tcgaaagatg gaataaacga actactggaa ataataatgg aggtgttcat gtataaaata
    14641 actgccacta ttgaaaaaga aggtggcact cctactaact ggacaagata ttcaaaatct
    14701 aaattaacga aatcagaatg cgaaaaaatg ctctcaggga aaaaagaagc aggcgtgtcc
    14761 agagagcaga aagtaaagct gataaatttt aattgcgaga aacttctgtc ctcgtgagtt
    14821 gcattatata caaattaaaa cttcatagct gattattaat aatcaacatc aggcgtcaat
    14881 ttcagtctaa cattggcgcc tgccagaggt gatgcgatgg cacaagtaat ctttaatgaa
    14941 gagtggatgg ttgaatacgg cctgatgctt cgcactggtc tgggggccag acaaattgaa
    15001 gcataccgcc agaactgttg ggtggagggc ttccacttca aacgagtatc tcctttaggt
    15061 aagccagaca gcaaacgagg gattatctgg tacaactatc caaagataaa tcagtttatc
    15121 aaagactcat gatatgtcta aattaccaac aggtgtcgag attagaggta gaaacattcg
    15181 catctggttc atgtttcgag gaaaacgatg tcgggaaaca ttaaaaggct gggagattac
    15241 aaacagtaat attaaaaagg ccggaaattt aagagcgctg atagttcatg aaataaactc
    15301 cggtgaattt gagtatttaa gacgttttcc ccagtccagc actggggcaa aaatggtgac
    15361 aacgagagtc ataaaaacgt tcggggagct ttgtgatatc tggacaaaaa ttaaagagac
    15421 agagttaaca acaaacacaa tgaagaaaac gaaatcacaa ttaaaaacac tcagaataat
    15481 aatttgtgaa agtaccccga tatcatatat tcgttatagc gatatcttaa actaccggaa
    15541 tgaactgctg catggagaaa cgctttacct ggataatcca agatccaaca aaaaaggaag
    15601 aaccgtgcgc acagttgata actatatcgc cctgctctgt tcgctgttac gttttgcgta
    15661 tcagtcggga tttatatcaa ccaaaccatt tgaaggagta aaaaaattac agcgaaacag
    15721 aataaagcct gacccgttat ctaaaacaga attcaatgca ttaatggaaa gtgaaaaagg
    15781 acagagccaa aacttgtgga aatttgccgt ttactccggg cttcgtcacg gggaactggc
    15841 agctctggcg tgggaggatg tggatttcga gaagggaact gtgaatgtca gaagaaacct
    15901 gacgatactg gatatgttcg gtcccccaaa aacaaatgcc gggatccgga cagtaacatt
    15961 actgcagcct gctcttgaag cactgaaggt gcaatacaaa ctgaccgggc atcatcgcaa
    16021 aagcgaaatc accttttatc atcgggagta cggcagaacc gaaaagcaaa aactgcattt
    16081 tgttttcatg cccagggtgt gtaacggaaa acagaaacct tattactcgg taagcagttt
    16141 gggggcaagg tggaatgcag cagtaaaacg tgctggtatt cgccgccgta atccgtacca
    16201 tacgcggcat acttttgcct gctggctgtt gacggcagga gcgaacccgg catttatagc
    16261 cagccagatg gggcatgaaa ctgcgcagat ggtgtatgaa atttacggta tgtggattga
    16321 tgatatgaac gacgaacagg tagccatgtt gaatgcgcgg ctatcgtagt tgcaaagttt
    16381 gcccccaatt tgccccattt agtaccagag aaccgaaata atgcaagaaa atcaaaagaa
    16441 tacgaagaaa gaacaataca acctgaacaa attacaaaaa cgtctgcgtc gtaacgtggg
    16501 cgaagccatt gctgacttca atatgattga agaaggcgat cgcatcatgg tttgcctctc
    16561 cgggggtaaa gacagctata ccatgctgga gattctgcgc aatttgcagc aaagcgcgcc
    16621 aatcaatttt tcgctggtgg ctgttaacct cgatcaaaag caaccgggct tcccggaaca
    16681 cgttctgccc gagtatcttg aaaagctggg cgttgagtac aagattgttg aagagaatac
    16741 ttacggtatc gtgaaagaga agattccaga gggcaaaacc acttgctcac tgtgttctcg
    16801 ccttcgtcgc ggtatccttt atcgtaccgc aacggaactg ggggcgacga agatcgcgtt
    16861 gggtcaccat cgtgacgata tcctgcaaac gttgttctta aatatgttct acggcggcaa
    16921 gatgaaaggt atgcctccga aactgatgag cgatgatggc aaacatatcg ttattcgtcc
    16981 gctggcctac tgccgcgaga aagatattca gcgatttgcc gatgcaaaag cgttcccgat
    17041 tattccgtgc aacctgtgcg gttcacagcc taacctgcaa cgtcaggtga ttgctgacat
    17101 gttgcgtgac tgggataaac gttatccagg gcgtatcgag acgatgttca gcgcgatgca
    17161 gaatgtggtg ccgtcgcatc tgtgcgatac caacctgttc gattttaaag gcattaccca
    17221 cggttctgaa gtggttaacg ggggtgatct ggcgtttgat cgcgaagaga tcccactaca
    17281 accggcgggc tggcagccag aagaagatga aaatcagttg gatgagttac gactgaatgt
    17341 ggttgaagtg aaataaccag gatagcgccc gatgcgcaag cgtatcgggc tactcttatg
    17401 gaggccggat aagacgcggc cagcgtcgca tccggcaatc ccgaataaga tgtttactct
    17461 tgcacccggc aattcaacat ttcattattt taataaccgc acccggcacg tttttccttt
    17521 aatcttcccg ccctgtaact gtttccatgc tttatgagca acagcctgac ggaccgcgac
    17581 atagacatgc gccggatgca cggcgatttt gccaatatct gcgccatcaa gcccgatatc
    17641 tcctgtcagt gcacctaata catcacccgg gcgcattttg gcttttttcc cgccatcgat
    17701 acacaacgtt gccatttctg cttccagcgg cacaatggaa ctattagctg gcggcgtttg
    17761 ccagttaagt tttatctgca acatgtcaga aatgatattg gcccgctgtg cttcttccgg
    17821 agcacagaaa ctgatcgcca gaccgctatt tcctgcacga gctgtacgac cgatgcgatg
    17881 tacatgaact tcagggtccc acgccagctc aaagttcacc accagctcaa gcgatttaat
    17941 atccagacca cgcgcagcaa catcagtagc aaccagtaca cgggcgctac cgttagcaaa
    18001 acgtaccaga gtctgatcgc gatcgcgttg ctccagatcg ccgtgtaacg acaatgcact
    18061 ttgccctact tcattcagcg cgtcgcagac agcctggcaa tcttttttgg tattgcaaaa
    18121 caccacgcaa gaggatggct gatgcaagct taataaccgt tgcaacagag gaattttgcc
    18181 tttgctggat gtctcataaa attgttgttc aatgggtggc aaagcatctg ttgagtcaat
    18241 ttcaatcgcc aaaggatcgc gttgtactcg tccgctgatt gcggcgatgg cttccggcca
    18301 ggttgccgaa aacagaagcg tctgtcgaga tgcaggcgca aaacggatga catcatcaat
    18361 ggcatcgcta aatcccatat ccagcatgcg gtcggcctca tccatcacca aagtattcag
    18421 cgcatccagt gataccgtgc ctttttgcaa gtgatccagc aaacgacccg gcgttgccac
    18481 gataatatgc ggcgcatgtt gcaacgaatc acgctgcata ccgaacggtt gaccaccgca
    18541 caacgtcaaa attttggtat ttggcagaaa acgcgccagc cgacgcaatt cacctgccac
    18601 ctgatccgcc agttcacgcg taggacacag cactaaagcc tgggtttgaa atagcgacgc
    18661 atcaatttgc tgtaacaagc cgaggccaaa agccgccgtt ttgccgctgc cggttttcgc
    18721 ctgcacgcga acatcttttc cggcaaggat cgccggaagc gcggcggcct gcaccggcgt
    18781 catggttaaa taacccaact cattaaggtt cgtgagttgg gcgggaggca aaacattcag
    18841 ggtagaaaaa gcggtcacaa tctattctcg tggtcatcga cgcaaagtta gcaggcgcgt
    18901 atcctcgcag atctacgctc acgatgcgac aatttaatcg gttcttcatc aggtggtggg
    18961 tcaggcatgg gttgcgggcg agggatcgga tcgggcactg gaacaggatc gccaggaatc
    19021 ggttcaggga caggaatttg caaataaata agtgtcgtca tatttccctc cggtcattgg
    19081 gtggactctt aaagggtaga cgctgataaa taacaggcaa aaaaaagccg actcatcaaa
    19141 gtcggcgtcg tacgaatcaa ttgtgctatg cagtaattca aaaaaggaag taagacaata
    19201 tggagcgcaa cgcccatcgc ttgacgttgc attcacctgc aagggagata ttgccctgaa
    19261 tgggtagaga gtttattgac ttcgctcaaa ctttgcggcg tttttgtata cagacagccg
    19321 gaaaaattgc ttttgttaca accatttact acgatgcaac cataaagcaa caccaccaat
    19381 aagaacaact aacagaatac aaaaaattga aaatccgaat tgccacccgc cgccagggat
    19441 cccaccaagg ttgacgccaa ataaccctgt cagaaaggta ctgggtaaaa agaccattgc
    19501 catcaatgac attgtatagg tacgacgagc taaattttcc tgcatcacct gagcgatttc
    19561 atccgccatc acgccagtcc gtgctataca ggcgtcgatt tcgtcaagac cgcgcccaag
    19621 gcgatcggca atatcctgca tccgacggcg ttggtcatcg ctcatccacg gcaaacgttc
    19681 actggcaaga cgagcataaa catcacgttg cggtgccata tagcgacgca tcacgattaa
    19741 ttgtttgcgc agcagagcca ggaatccacg cggtggaatt tgctgatcaa ggagattatc
    19801 ttcaaggtcg ataattttat cgtgcagctg ctcgataaat tcgctggaat gatcggtcaa
    19861 cgcatcgcac acatccacca gccaccctcc gcaatcggtc ggacccgtgc cctcttccag
    19921 atcgctcacc acatcgtcca gcgccagcac tttgcgttgt cgggtcgaaa caattaaccg
    19981 cccgtccata tatacacgca tggcgaccag ttgatcgggg cgttcatcgg tgctgccgtt
    20041 tatacagcgc aatgtaatca gcgtgccttc accgagacgg ctgactcggg gccgagtgct
    20101 ctcgcctgcc agcgcatcac gtacgttatt gggaagcagc ggtgttgtcg ccagccattg
    20161 ggcgctttca tggtgtacat aattaaggtg gagccagcag ggatgcgctt catcaatcac
    20221 atctgtattt tccagcggtt taacgccgcc tctaccatcc agcatccagg caaatactgc
    20281 atccgggaca ttaacgtccg atcccttaat cgcttccaca gtgcctccat catcaacgca
    20341 ttattttgta gtctagcctt ctggccctgt tacgcaacat ctcatcaccc cattaccctg
    20401 aaatgattaa taaaattctg tctaaattga atacaaaaag caaaatgctt ttccgtatac
    20461 aaaccgtgtg aagtgttaaa tagcgtctat cattatcaga attatctgat catatgacgt
    20521 ggcttttttg cgatcggata gcaacaaaaa ttgataaaaa taacgggatc tcaatgatta
    20581 cgcacaactt caataccctg gacttactca ccagtcctgt ctggattgtt tcgccctttg
    20641 aggaacagtt aatttatgcc aatagcgcgg cgcgactgtt gatgcaagac ctcacgttta
    20701 gtcagctacg aaccggaccc tattccgtct cctcacaaaa agaactgccg aaatacctct
    20761 ccgatctgca aaaccaacac gatattatcg aaatcctcac tgttcagcgt aaagaagagg
    20821 aaacagcatt aagctgtcgg cttgttttgc gagagctgac agaaacagaa ccggtgatta
    20881 ttttcgaagg tatcgaagcg ccggcaacgc tgggtttaaa agccagtcgc tcggcaaatt
    20941 atcagcgcaa aaaacaaggt ttttatgcgc gcttttttct gactaactct gcaccaatgt
    21001 tgttgattga cccctcacga gatggccaaa tcgtcgatgc taacctcgcc gcgctcaatt
    21061 tctatggtta taaccatgaa acgatgtgcc agaaacatac ctgggaaatt aatatgctcg
    21121 ggcgtcgcgt catgcctatc atgcatgaaa tttcgcattt acccggcggt cataaacctt
    21181 tgaattttgt tcataaactg gcggatggat ctactcgtca tgtgcagacc tatgccgggc
    21241 cgattgaaat ttatggcgac aagctcatgt tatgtattgt gcatgatatt actgagcaaa
    21301 aacggctgga ggagcagctg gaacatgctg ctcaccatga cgcgatgacc ggattactga
    21361 atcggcgaca gttttatcac attaccgagc caggccaaat gcagcatctc gccatcgctc
    21421 aggattacag cttgttgctc atcgacaccg atcgttttaa acacattaac gatctctatg
    21481 ggcattctaa aggtgatgag gtgttatgcg ccctcgcccg cacccttgaa agttgcgctc
    21541 gcaaaggcga tttggtgttt cgttggggag gcgaagagtt tgtcttattg ctaccaagaa
    21601 ccccactgga taccgcgctt tcgctggctg aaactatccg tgtaagcgtg gcaaaagtga
    21661 gtatttcggg cttaccacgc tttaccgtca gcattggtgt ggcgcatcac gaaggaaatg
    21721 aaagcatcga tgaactgttt aaacgcgttg atgatgcttt gtatcgggcg aaaaatgatg
    21781 gacgcaaccg cgtgctggcg gcataagccg cggatgcgtc tcgagatcaa cgactgcgct
    21841 tagcgtggcg ctcccagttt tcttgcttcg cctgcgccgt tttacgtagt gcgacgtaac
    21901 acgccccgct gccgccatga tgcggtagcg cagtgcaata tgcctgaaca tcatcaaatt
    21961 cggtcagcca gcgcgccaca tagctgcgga caatattggc atgcgattta tcatcccgtc
    22021 ctttgccatg aataatcagc acgttacgca aaccatcagc catggcttgt tgaatgaaac
    22081 tgaacatcat tttgcggcac tcttccaccg gctggcgcaa aagattcagg ctcgcctgtt
    22141 gcggatattt accactgcgc agcttatcca gcaccccatg ttgcaaccct tcccgccgaa
    22201 actccagcgg ctgacttagt gggatgatgt cgagaaatcc ggtggtgagg aaattatcaa
    22261 gctgcagcgt gtcgatacgc tgcggcgcac gttggttacg cgttggatgc cagtggacat
    22321 cggtagcacg tttcagcggc tggacatctt ccatggcgtc aagaaacagc gatttgtcgt
    22381 caaggttcat gttacatcct cccgcaatta agagcgcgat atgataacca gaccgggtcg
    22441 gtccaacaac gtattaccca aaattccagt aataagttcc aaatattgcc gatattttaa
    22501 gcaaaatgct tatgcatgat tattcattca cgatattaat aatgtaactt atattttcgt
    22561 gaaatctgtc actgaagaaa attggcaact aaaggttaaa accgttataa cacagtcacc
    22621 ggcgcagagg agacaatgcc ggacttaaga cgcggatgca ctgctgtgtg tactgtagag
    22681 tctggcggat gtcgacagac tctatttttt tatgcagttt taactttgca gatagccgca
    22741 ttctcgccgg aattgcgtga ttaatgacgc ggtcagtggt gtctggcgac tatcacgccg
    22801 ctgaatcaaa taataggccg ctttcggtaa aatttcgcta accggcaaca tcaccagccc
    22861 ctgtccgtgc aagggatcgc agcccatttc ttcaggcagt atgctgagaa aatcactttt
    22921 tgccaccaga ctgatacagg ctgagaacgt ctcgcagact acaccgacct gtggcgtttg
    22981 cgcctgatcg tcaagcaatt cactcaactg tttgtagtaa ctgccgtgtg gcgtcggcat
    23041 tgtccagctg taatccagta actgtttgat cgaacgggca ccaatggcgg ggtgtcccgg
    23101 gcggcaaaag atcgcgaatt gcttttccag taatttctca aaagtaaatt cgtggtcgta
    23161 cggtccctga taataggtat tgatggtgaa atccaattct ccctgacgca attcattaat
    23221 catcgacacc agttgccctt ccataatgcg tacttttacc tgcggatgct gctgatgaaa
    23281 acgagatatg acagctggca tcagactgcg ggaaatactg gcccccatgc cgatattaat
    23341 ctgccctgcc agttgccctt gtcgttggcg aatttcctct tgcgctgcgc gcagctcttc
    23401 aagaataaga ctggcgtgct gataaaaact ttcaccggca tcagttaacg tcacgccttt
    23461 actacggcga aaaaagagtt gcgccgctaa tccttcttcc agctcctgaa tagatttact
    23521 cagtgccggt tgcgacatat tcaacattcg gctcgctccg cgaatgctgc cctgacgagc
    23581 cacttcaaca aaagcacgaa tttgatgaat ttttacctga aaagccatga cgccaccgat
    23641 aaccgttatt tatcagacca aagaaactgg catctacttt aatgcagatg attgtgtcag
    23701 ggtaatttat gaacggttaa aactgtgaaa aatcagttag tgataagtaa aaactatcgc
    23761 tacatgaacc gggtcacact ttttactgat gacgggaaag gttatggagt ctttgaatca
    23821 atttgttaat tcgcttgccc caaaattatc gcactggcga cgtgattttc atcactatgc
    23881 agagtctggc tgggtggaat tccgcactgc cacccttgtt gcggaagaat tgcagcagct
    23941 cggctattca ctggcgctgg gccgcgaagt agttaatgaa agtagccgga tgggactacc
    24001 tgatgaactc actctacaac gcgaattcga gcgcgctcgt caacagggtg cgctagcaca
    24061 atggattgcg gtttttgaag gtggtttcac tggtatcgtc gccaccctgg ataccggtcg
    24121 ccccggtccg gtgatggctt tccgtgtcga tatggacgcg ctggatctca gtgaagagca
    24181 ggatgtcagc catcgcccct accgcgacgg ttttgcgtca tgtaacgccg gaatgatgca
    24241 tgcctgtggt catgatggac ataccgccat tgggcttggg atggcgcata cccttaaaca
    24301 attcgagtcc ggactacatg gcgtcatcaa actgattttt cagcctgcag aggaaggtac
    24361 gcgtggcgcg cgggcgatgg tcgatgcagg tgtcgtagat gatgttgatt attttactgc
    24421 cgtgcacatt ggcactggcg tacctgcggg caccgtggtg tgcggcagtg ataattttat
    24481 ggcaaccacc aaatttgacg cgcacttcac cgggaccgcc gctcacgcag gcgcaaaacc
    24541 agaagacggt cacaatgcct tgttggcggc agcacaagca actcttgcac tgcatgcaat
    24601 cgccccgcac agcgaaggag cttccagagt aaacgtgggc gttatgcagg caggaagcgg
    24661 ccgtaacgtt gttcctgcct cggcgttgct gaaagtggaa acacgcgggg ccagcgacgt
    24721 cattaatcaa tatgtttttg accgtgcaca acaagcgatt cagggcgcag caaccatgta
    24781 tggtgtcggc gttgaaactc gtctgatggg tgcagctacc gccagttctc cttcgccgca
    24841 atgggtcgca tggttgcaaa gtcaggcggc tcaggtcgcg ggggtcaatc aggccattga
    24901 acgtgttgaa gcgcctgcgg gttccgaaga tgccacatta atgatggccc gcgtgcagca
    24961 acatcaaggg caagcctcct acgtggtgtt tggcacacag ctggcggcag gtcatcacaa
    25021 cgaaaaattc gattttgacg agcaggttct cgctattgcc gtcgaaacgc tggcgcgcac
    25081 cgcgctcaat tttccctgga cgcgaggtat ctgatgcagg aaatctatcg ttttatcgac
    25141 gatgcgattg aagccgatcg ccaacgttat accgatattg ccgatcaaat ctgggatcat
    25201 ccagaaacac gttttgaaga gttctggtca gcggagcatc tggcttcggc gctggaatct
    25261 gcaagcttca ccgttacccg caacgtaggc aatatcccaa atgcatttat tgcttcgttt
    25321 ggtcaaggca aaccggttat cgccctgctg ggagaatatg acgccctggc aggtttaagt
    25381 cagcaagctg gttgcgcgca acctacatcc gcgacgcccg gtgaaaatgg tcacggttgc
    25441 ggacacaatt tgctgggaac cgccgccttt gccgctgcaa tagccgtcaa gaaatggctg
    25501 gaacaatatg ggcaaggcgg cacagtgcgc ttttatggtt gtcctggcga agaaggcggc
    25561 tcgggtaaaa cgttcatggt ccgcgagggg gtatttgatg atgtggatgc ggcactcacc
    25621 tggcacccgg aagcctttgc cggcatgttc aatacccgca cgctggcaaa cattcaggca
    25681 tcatggtgct ttaaagggat cgcagcacat gccgcgaatt cccctcattt gggacgcagc
    25741 gcccttgatg ccgtaacgtt gatgaccact ggcaccaact tcctcaacga acatattatt
    25801 gaaaaagcgc gcgtacacta tgccatcaca aatagcggcg ggatctcgcc caacgtggtc
    25861 caggcgcagg cagaagtgct ttatcttatc cgtgcccccg aaatgaccga cgtgcagcat
    25921 atttatgatc gggtcgccaa aatcgccgaa ggtgcggcat tgatgaccga aaccacggtt
    25981 gaatgccgct tcgacaaagc ctgttccagt tatctcccga atcgcacctt agaaaatgcc
    26041 atgtaccatg ccctatccca ttttggtacc ccggaatgga actccgaaga actggctttt
    26101 gcgaaacaaa ttcaggctac gctcaccccc aacgatcggc aaaacagtct gaataatatc
    26161 gccgcaaccg gtggcgaaaa cggcaaggtt tttgcactac gtcatcgtga aacggtactg
    26221 gcgaatgagg tcgctccata tgccgccacc gataacgtgc ttgcggcatc gactgatgtc
    26281 ggcgacgtca gttggaaact gcctgttgcc cagtgtttca gcccctgttt tgccgtcggt
    26341 acaccgctac atacgtggca actggttagc caggggcgaa catctattgc tcataaagga
    26401 atgctgctgg cggcgaaaac tatggcagca accacagtca atctcttcat tgattcaggg
    26461 ctattgcaag aatgccaaca agagcatcag caagttacgg acacgcaacc gtatcactgc
    26521 cctatcccga aaaacgtgac accgtcacct ttaaaataac aacaacgcaa acacaacaac
    26581 cgaggaatgc ccatgagtat gtcatccata ccgtcgtcct cccaatccgg gaagctctat
    26641 ggctgggtcg aaagaattgg taacaaggtt ccccatcctt ttttgctctt tatctatttg
    26701 ataatcgtac tcatggtgac gacggcaatt ttgtcagcct ttggcgtcag tgcgaaaaac
    26761 ccgaccgatg gtacgccggt ggtggtgaaa aacctgctca gtgtggaagg attacactgg
    26821 tttttaccca atgtgattaa aaactttagc ggttttgctc cacttggagc gatcctggcg
    26881 ctggttttag gtgccggcct agcggagcgc gtcggcttac tgccagcgct aatggttaaa
    26941 atggcatcgc atgttaatgc ccgctacgcc agttatatgg tgctgtttat tgcttttttc
    27001 agccacattt cttccgatgc ggcgttagtg atcatgccac cgatgggtgc gctgattttt
    27061 ctggcggtgg gcaggcatcc agttgcaggt ttactggctg ccattgcagg cgtaggttgc
    27121 ggctttacgg ctaatttact gattgtcaca accgacgtgt tgctgtcggg gatcagcacg
    27181 gaagcggcgg ctgcgttcaa tccgcaaatg cacgtcagtg taattgataa ctggtatttt
    27241 atggccagct ccgtagtcgt actgacgatt gttggcggct tgataaccga caaaatcatc
    27301 gagccacggt taggtcaatg gcagggaaac agcgatgaga aactgcagac attgaccgaa
    27361 agtcagcgtt ttggtttacg catagcaggt gtcgtatcgc tactttttat tgctgcgatc
    27421 gcgctgatgg tgatcccgga aaacgggata ttgcgcgatc cgattaatca caccgtgatg
    27481 ccatcaccct ttattaaagg tatcgtgcca ctaatcattc tttttttctt tgtggtttcg
    27541 ctggcttatg gcatcgctac ccgcacaatt cgacgtcagg cggatttacc gcatttaatg
    27601 attgaaccga tgaaagagat ggcgggattt atcgtgatgg tttttcccct cgcccagttt
    27661 gtcgccatgt ttaactggag caacatgggg aaattcatcg ccgtggggct gaccgatata
    27721 cttgaaagtt cagggcttag cggcatcccg gcgtttgtcg gtctggcgtt gctttcctct
    27781 ttcttatgca tgtttattgc cagcggttcc gcaatctggt cgattctggc ccccattttc
    27841 gtaccaatgt ttatgctact tggctttcac ccggcatttg cgcaaatcct ctttcgtatt
    27901 gccgactcat ccgtattgcc tttagcgccg gtatctcctt ttgttccact gtttcttgga
    27961 ttcctgcaac gctacaaacc agacgcgaaa ctgggtactt actattcgtt agtcttgccc
    28021 tatccgctta tctttttggt ggtatggctg ctgatgttgc tggcgtggta tcttgttggt
    28081 ctgccgatag gtccggggat ttacccacgt ttgtcttaag agagaacgga tgctgagatt
    28141 acttgaagaa aaaattgcca cgccactggg tccactgtgg gtgatttgcg atgagcaatt
    28201 tcgcctgcgg gcggttgaat gggaagagta cagcgaacgc atggtgcagc tgctggacat
    28261 ccattatcgc aaagaaggct atgagcgcat ttctgccacc aacccaggcg gtttaagcga
    28321 caagcttcgt gattattttg ccggtaatct tagcattatt gatacgcttc ccactgccac
    28381 aggggggacg ccatttcagc gcgaagtctg gaaaactcta cgcactatcc cctgcgggca
    28441 ggtaatgcat tacggccaac tggctgaaca attgggccgc cctggcgcgg cgcgtgccgt
    28501 tggtgcggca aacggatcga atcccatcag catcgtcgta ccttgccatc gggttattgg
    28561 ccgaaacggc accatgaccg gatatgcagg cggagttcag cgaaaagagt ggttattgcg
    28621 ccacgaaggt tatcttttgc tgtaaacatt aaacaatttg tgccagcttg ttcacacttt
    28681 tatgtaaagt tacccttaac aacttaaggg ttttcaaata gatagacata tatttacatc
    28741 taatatcgga attctctgct gttaaggttt gcttagactt acttgctccc taaaaagatg
    28801 ttaaaattga caaatatcaa ttacggcttg agcagaccta tgatcccgga aaagcgaatt
    28861 atacggcgca ttcagtctgg cggttgtgct atccattgcc aggattgcag catcagccag
    28921 ctttgcatcc cgttcacact caacgaacat gagcttgatc agcttgataa tatcattgag
    28981 cggaagaagc ctattcagaa aggccagacg ctgtttaagg ctggtgatga acttaaatcg
    29041 ctttatgcca tccgctccgg tacgattaaa agttatacca tcactgagca aggcgacgag
    29101 caaatcactg gtttccattt agcaggcgac ctggtgggat ttgacgccat cggcagcggc
    29161 catcacccga gcttcgcgca ggcgctggaa acctcgatgg tatgtgaaat cccgttcgaa
    29221 acgctggacg atttgtctgg taaaatgccg aatctgcgtc agcagatgat gcgtctgatg
    29281 agcggtgaaa tcaaaggcga tcaggacatg atcctgctgt tgtcgaagaa aaatgccgag
    29341 gaacgtctgg ctgcattcat ctacaacctg tcccgtcgtt ttgcccaacg cggcttctcc
    29401 cctcgtgaat tccgcctgac gatgactcgt ggcgatatcg gtaactatct gggcctgacg
    29461 gtagaaacca tcagccgtct gctgggtcgc ttccagaaaa gcggtatgct ggcagtcaaa
    29521 ggtaaataca tcaccatcga aaataacgat gcgctggccc agcttgctgg tcatacgcgt
    29581 aacgttgcct gatttttccg cataactcac tatccttctg tcatatcatt aaatttttct
    29641 gatttattga tctggcagaa ggttcatcac tgtttcattc accagatatg ggttaatctt
    29701 ttaattacaa actgcgttga cagttgttgt aaggagaccc tgtatggcta tgtatcagaa
    29761 catgctcgtt gttatcgatc ctaaccagga cgaccaacca gcattgcggc gagctgttta
    29821 tttacatcaa cggattggtg gcaaaattaa agcctttttg ccgatctatg acttctcata
    29881 cgaaatgacc accctgctct ccccggacga acgtaccgct atgcgtcagg gcgtcatcag
    29941 ccagcgtaca gcctggatcc acgagcaggc aaaatattat ctcaatgctg gcgttcccat
    30001 tgaaattaaa gtggtctggc ataaccgtcc cttcgaagcc atcattcagg aagtgatcag
    30061 cggcgggcac gatttggtgc taaaaatggc gcaccaacat gaccgtctgg aagcggtgat
    30121 ttttacgcca acggactggc atctgttacg caaatgccca agcccggtgt ggatggtgaa
    30181 agaccagccg tggccggaag gaggcaaggc gctggtggcg gtgaatctcg ccagtgaaga
    30241 gccgtatcat aatgcgctca atgaaaaact ggtcaaagag acgatcgaac tggcagaaca
    30301 agtcaaccat accgaagttc atctggttgg cgcttatccg gtaacgccaa ttaatatcgc
    30361 gattgaactg ccggaatttg atccgagcgt ttataacgat gccattcgtg ggcaacattt
    30421 gctggcaatg aaagctctgc ggcagaaatt cggcattaat gaaaacatga cgcacgtaga
    30481 aaaaggtctg ccagaagagg tgattcctga tttggcggag cacttacagg cggggattgt
    30541 ggttctgggc acggtaggac gcaccggtat ttcagcagca ttcctcggca acacggcgga
    30601 acaggtgatt gatcatcttc gctgcgatct gttggtcatt aaacctgacc agtatcagac
    30661 acccgttgaa ctggatgacg aagaagacga ttaacgactc ttcaataact gacaaggccc
    30721 gagttatcgg gcctattttt tacttactgc tcttcgccgc caaggaaata aattcccaac
    30781 gggattgcca gcaacacagt aaagaccagg ctataaacaa aaatcatcga tgactgaatc
    30841 acatacattg atgtcgtcca ctcagacagc ggaatattgt actgttctat aacgccgccg
    30901 atagtcgcgc gagtcacaac cgacgccgca ataatgaaaa ccgccaacaa accaaagaga
    30961 aatttcttcc ctttcgctga cttcagtttc gccataatca tgatgtaatc cttgtgcaga
    31021 caaatttctt gttacctaaa cgtaacaata ccatgacatt tcaccgttgt ctgctctgaa
    31081 aacctcacct cttagctgga tttacaatca acgcattgat tagttagcta atgttgctac
    31141 ttccttccct gactattgat gatctgaatg aattgtcgcg gtaaaatagc cccgccaggg
    31201 gtttccggca tgacgacaat tatctggagg agcctgataa aacaatgatc gctgaactgt
    31261 ttacaaataa tgcgcttaat ctggtcatta ttttcggtag ctgcgcagca ttgattctga
    31321 tgagcttttg gtttcgccgc ggaaatcgta aaagaaaagg ttttttattc catgcggtgc
    31381 aatttttaat ctacaccata attatcagtg ctgttggtag cattattaat tatgttatag
    31441 aaaactataa actcaaattt atcaccccag gcgttatcga ttttatctgt acgtccctga
    31501 ttgcggttat tctgacgatt aagctatttt tgctgattaa tcagtttgaa aaacagcaga
    31561 ttaaaaaagg tcgcgatatc accagtgcgc ggattatgtc gcgcattatc aaaatcacca
    31621 ttattgtggt gcttgttctg ctttatggcg aacatttcgg catgagcctt tctggcttgc
    31681 tgacctttgg tggtattggt ggtctggctg tcggtatggc cggtaaagat attctgagta
    31741 atttcttttc cgggatcatg ctctatttcg accgtccttt cagtattggc gactggatcc
    31801 gttcaccgga cagaaatatc gaaggtacag tagcggaaat tggctggcga attaccaaaa
    31861 ttacgacctt tgataatcgt ccattgtacg taccgaactc gctgttttcg tcgatcagcg
    31921 tagaaaaccc aggacgaatg accaaccgcc gcattaccac gaccattggt ttacgttatg
    31981 aggatgcggc aaaagtgggc gttattgtcg aagccgtacg tgagatgctg aaaaatcacc
    32041 cggccatcga ccagcgacaa accttactgg tttatttcaa ccagtttgcc gactcgtcat
    32101 tgaatattat ggtttattgc tttaccaaaa ccacggtatg ggctgaatgg cttgctgcac
    32161 agcaagacgt ttatttgaag attatcgata ttgtgcagtc acacggcgcg gactttgcct
    32221 tccccagcca gacgctgtat atggataaca ttacaccgca ggaacagggg cgctaaatca
    32281 gacatcactg gcgttatcca caagggtaac gccagttccc atcacatcaa tgcttcacaa
    32341 tatacatagt ccggctgtac gccacatctt ccgggttatt aatgggataa cctttcagcc
    32401 acggcttgat taatcgtcca ttggtatatt gataaattgg tgcaatcggt gcttgctcca
    32461 tgaggatttt ttctgccgcg ttgtaatcgg cattacgcgc tttaacggta ttttccgtcg
    32521 atgcctgggc cagaactttg tcgtatgccg gattgttaaa gcgtgaaata tttcctgaat
    32581 gcgttgacgt taataatgtc aggaaagtgg agggttcatt ataatccccc acccatgagg
    32641 cgcggataac atcaaaattg ccggtgttac ggctatcgat ataggttttc cattcctgat
    32701 tttgcaattt aacatctacg ccaaggttct ttttccacat cgatgctaca gcaatcgcaa
    32761 ttttttgatg gttttctgaa gtgttataca aaagcgtcag cttcagcggt ttttgcggac
    32821 cataaccagc tgcgctcaac aaagtttttg cctgcgcatt cagttcttcc tgactcattt
    32881 gttcaaacgg cgaaggttcc ggcgtaaatc cggcggtaac atctggtgta aaatgccacg
    32941 ctggcttttc gcccgtccct aatacttttt cggtcatcag gcggcgatct atcgtcatac
    33001 ttaatgccag acgaacgcgc tgatctgccg tcggcccttt ttgcgtgtta aacgcataat
    33061 aataggtccc gagctgcggc ggcgtataaa cctgccccgg aatatccttc aacagcttct
    33121 gatacatatt tttcgggaag gattcggtga tatcaatatc ccccgcgagg taacgcttag
    33181 tggctgcgga ttcctgatta attggcagga aggtcacttt ttgcagtacc gttttggcgt
    33241 tatcccaata atgggtattc ggtaccacga ccagtttttc attgactacg cgttctttaa
    33301 gaacataagc gccattgccg atcagatttc cgggtttcgt ccactcttta ccgctttcta
    33361 cgttggcttt ttgcaccggg aagaaggcaa agttagcggt taaattcaca aaccacggca
    33421 acggtttatc aagctgaatt ttcaaggtat gggcatcaac tgcggtgacg ccaagctggt
    33481 caggcgtagc tttaccatca ataattgcct gtgcgttgtt gattcccgcc agcgcggcaa
    33541 accatgcaaa tggcgatagc gttttcgggt ccaccagacg ttgccagctg tagacaaaat
    33601 cttgcgccgt taccggtgtg ccatccgccc attttgcgtt atcgcgcagg gtaaaagtcc
    33661 agatacggtt gtcattactt ttccactgag tcgcaacgcc ggggacaatc tcccctttct
    33721 cgttctgatt caccagtcct tcaaacagat cgcgaatgac ctgaatctct ggcaggccca
    33781 cggctttagc gggatccagc gacgcaggct catctttaat gtggcgcacc agctcctgct
    33841 tctctgccag tactgtgccg ctcggaactt ctgcagcata cgaaagagaa atgctgctga
    33901 ccaacagcgc acaacacgtg actgaaacag agtgcttcat aagtttccct ctaaccgaca
    33961 ttaaaattga tgcgtaatta tttgtttcgc cttaaagaaa tgcaaacaac ttccatcaaa
    34021 aaagtgacac aggaagcata aaatgtttta tgtatcaata tattaaatca gatttagtgt
    34081 aaataatcga cgccaaaatg cggcaaagca catagaacac cgaacactac gttcaggctt
    34141 cgcacgttca aaccagtttt cggtatcaaa atcagcatct gtcgccattg tacgaagaat
    34201 aaaaaataac caaaacgttg aaaggaactg agaatacgtt aagagagaaa ttaaattaat
    34261 gtatcagcaa gtagtgctaa acagcacctt tatacttcag cctatctata aataatgaga
    34321 atgccgagcc agcatgtcga cggtgtggat agtacaggtg ataaccgggt aaatctggtg
    34381 tgaatttatc caaaacacgt atcagttttt tttctttaat agcccgctca acctgatcat
    34441 aaggtagata cgccaatcca tgcccatcaa ttgcagcatc aatgatcagg tctatcgtat
    34501 tcagtaaaag ctgaccttcc atgcgaacac gaacttcacg tccaccgcgt attaatctcc
    34561 agcgatttgc tttacccgat gtgggaagat acaaattaat tgcctgatga tctattaatt
    34621 gtgacactga cgttggaaca cttcggcgag aaaaataatc cggtgagcca acaatagcca
    34681 ttggtatatc tggcccgatt cgaatggcga tcatatcttt atccatctcc ccacccagac
    34741 ggacgcctgc atcaaaacgt tcagaaacga catcggtcaa accataatca atggtgagct
    34801 gaatatcaat ttcaggatgc gatttcagga atgtgcgcat tgctggtaac aatatcgttt
    34861 ttgctgcatg ttctacagta gtaatacgta ttgtcccgga tgggcggttc tgcagatcgc
    34921 tcagggatgc catggctgaa tctatgtcat gcaacatagg gccaagaaca gacaaaagat
    34981 gctcgcccgc ttcagttgga acaacgctgc gcgtggttcg cgtcagaagc cgcaatccca
    35041 atcgttcttc tatacgacgc actatctggc ttaaagctga ctgcgccatg ctcaggcggg
    35101 ctgctgcacg agtgaagcta cgctcctctg caacgacgac aaacgccatc agatcagcga
    35161 tttcttcacg cttcattcag tatctccatg caatctatta atcatttaaa tgataggtct
    35221 aatcatgatt ttgggtctaa tcaacttaat gatcaatatc tatagtgata tcaccaaccg
    35281 ttaaaacgaa ccgacaactc catgaggaac ggaatgatga ataataaagt cagcttcact
    35341 aacagcaata atccaaccat ctctttgtct gcagtgatct atttccctcc aaaatttgat
    35401 gaaacccgtc agtatcaggc aattgtgtta tctcacccag gtgggggcgt taaagaacaa
    35461 acggccggaa cctatgccaa aaaactggcg gaaaagggat ttgtcactat tgcttatgac
    35521 gcatcttatc aaggtgaaag tggcggcgag ccgcgtcagt tagaaaaccc atacattcgt
    35581 actgaagaca tcagtgccgt gattgattac ctgacaacgc tttcttatgt cgacaatacc
    35641 cgaattggtg cgatgggaat ttgtgccggt gcaggatata cagccaatgc tgcaattcag
    35701 gatcgccgca tcaaggccat cggtaccgtt agtgcggtca atattggttc gatgttccgt
    35761 aatggttggg aaaacaatgt gaaatctatt gatgccctgc catacgttga agcgggttca
    35821 aacgcccgaa ccagcgatat tagcagcgga gaatatgccg ttatgccact ggcaccaatg
    35881 aaggagtccg atgcgccgaa cgaagaactg cgtcaggcct gggagtatta ccacacccct
    35941 cgcgcgcagt atccaacagc accgggttac gctactttgc gcagccttaa ccagattatt
    36001 acctatgatg cttaccatat ggcggaagtg tacctgactc agccgatgca gattgtggcg
    36061 ggcagccagg cagggagcaa atggatgagt gacgacctgt acgatcgggc atcaagccag
    36121 gataaacgct atcacattgt tgaaggcgca aaccatatgg atctttatga cggcaaagcc
    36181 tatgtggctg aagcaatttc agtattagct ccgttctttg aggaaactct gtaatgaaac
    36241 atattcaaat ccgcaatagt gatatggcct ggcatattgc tgccaatatt cagtttccac
    36301 caaattttga tgagtcaaaa cagtatccgg cgattatcag cgtccatcct tttggcagtt
    36361 gtaaggagca gacgtttggc aatatctatg gcaaagcatt ggctgaaaaa ggctatctcg
    36421 ttctcgctta tgacgccagt ttccagggag aatctggtgg ggagcctcgc tggatagaag
    36481 atccgacaca gcgcgtagag gatattagcc gtgttatcga ttatgcagta actctgccat
    36541 atgttaatgc tgaacgtatt ggcgtgctgg gagtgtgtgg gggtggtggc tatgccatta
    36601 atgccgcgct gacagaaaaa cgaattaaag cagtagtgag tattacgggt gttaatatcg
    36661 ggcgtctttt tcgggaaggt ttcagcaatt acgatccgat tggcgcactg aatgcaatgg
    36721 cgtcgcaacg aaccaaagag gctcgtggtg gagaattaca gatcaacgaa ttacttcccg
    36781 ccagcctgga tgcagcaaaa gcccatggag tgaccgaacg cgatgtttat gaagcaactg
    36841 actactataa aacaccacgc gggcaacaac cgggaggtgc gacaaaaatg ttgttctcac
    36901 atgcacagaa aacgctggcc tgggatgcct tcgcatttac tgaagtgtta ctgactcagc
    36961 cggtgatggt agtagttggt gaaaaagtcg gtgccttcgg tgcttatcgt gatggactgg
    37021 aagtctatgg ccgggcgatg gtttcgcagg atcgtcagtt agtttcatta cccgatttct
    37081 cacattatga actgtatgac aaaccggaag cagttcagga ggcgctggaa aaagttattc
    37141 cttttttcaa cacccatctg ggataagttt catgagaaat attatgaaaa atgtactgat
    37201 tcttggtgct ggcggtcaga tagcccgcca tgtgattaat caactggcag ataaacaaac
    37261 cattaaacaa actttatttg cccgtcagcc agcaaaaatc cacaaaccct atccaactaa
    37321 tagcaagatt attatgggag atgtactgaa tcatgcagca ctgaagcagg ccatgcaggg
    37381 acaggacgtt gtgtatgcca accttacggg ggaagattta gatattcagg caaattcagt
    37441 gatcgctgcg atgaaagcct gtgatgttaa acgtctgatc tttgttcttt ccctcggtat
    37501 ttatgatgaa gttccaggaa aatttggcga atggaataat gcagttattg gtgagcccct
    37561 aaaaccattc cgcagggctg cggatgcaat tgaggcttct ggactggaat atacaattct
    37621 tcgccctgcc tggctgactg atgaagatat tattgattat gagcttacct cacgcaatga
    37681 accattcaaa ggtacgatcg tatcacgtaa gagtgtcgca gcattaatca cagatatcat
    37741 cgataaacct gagaaacaca ttggtgataa tataggtatc aatcaacccg tgactgatgg
    37801 tgacaagcca ttattcatgt aaatcaatta catagttacc atcgtaatgt actatgtgca
    37861 gtacgattta ttaaacttat taaggtgaac tgatcaatcc gatgcgatta acatgtgtag
    37921 aaccagtaag aataaaatac gccatgtata taacattacg acttacatct aagtcagcat
    37981 aattctaata tctgcacatc aataaaaatg caaacaactt ccggcaaaaa agtgatacaa
    38041 gatcgatgac atagcgttga agaaaaggat ttgataatcc gcaaaatttg cacaacactg
    38101 cctgtaatac ttcctgaacc agagacgatc atgaccgtaa accgcccacg cgccgaacgc
    38161 ggcgcatttc cgcccggaac agaacattac ggacgttcat tattgggcgc gccgttaatc
    38221 tggtttcctg cccctgcagc cagtcgcgaa agtggtttga ttctggctgg cactcacggt
    38281 gatgaaaact cttcggtcgt cacgctctcc tgtgctctgc ggactttgac accttctttg
    38341 cgccgccatc atgtggtgct gtgtgtgaat cctgacggct gccagctggg gttacgggcc
    38401 aatgctaatg gtgtggattt aaacagaaac tttccggcgg cgaactggaa ggaaggtgaa
    38461 acggtttatc gctggaacag cgccgctgaa gaacgtgatg tcgtattact gacaggtgac
    38521 aaacctggct cagaacctga aacccaggcg ctgtgccagc ttatacaccg cattcaacct
    38581 gcctgggtgg tctcattcca cgatccactg gcctgtattg aagatcccag acacagcgaa
    38641 ttaggcgaat ggctggccca ggcgtttgaa ttgcctctgg taaccagcgt cggttatgaa
    38701 acgcctggct ctttcggcag ttggtgtgca gatctcaact tgcattgcat caccgcagag
    38761 tttccgccca tctcctccga cgaagccagc gaaaaatatc tctttgcgat ggcaaacttg
    38821 ctgcgctggc atcctaaaga tgcaattcgc ccgtcgtgaa ctgaagcgcc ggttccacat
    38881 ctaccgccag ccaggtcggt ccgtcaagat cggcgaaact gacctgcggc accagcggta
    38941 aagcggcgct aatggcacga gaggtacaca acatgcagcc cagcatcaga ctgaaacctt
    39001 gtgcacgcgc ttcagtcgcc agcgccagcg cttccgtcag accaccggtt ttatcgagct
    39061 taatgttaac catctcatag cgccctttca gcgccttcag attgctacgt gtatgacaac
    39121 tctcatcagc acaaatcggc aacggatgaa taaaattctc cagcgccgca tcgtcctgcg
    39181 caggaagggg ttgttcaagc atcgcaacgc ctaaatccgc caatagctgg caacgcgccg
    39241 ccaacccttc tgcacgccag gattcatttg catcaacgat cagcgtcgca tcgggcacag
    39301 ctgtgcgaat tgccaccatc cgctcactaa taagatggtt atccagcttc actttcagta
    39361 atttcgcgcc tgcctgccag agtgttgatg cactattggc catctgatca ggcgtaccga
    39421 tgactaccgt ctgtgcagtg ataactgtct cgggaagcgt tatgccgatc aaatcagcca
    39481 gcgattgctg ctgttttcgc gcggccagat cccacaatgc acaatccagc gcattacgtg
    39541 ctgcgccggc agggagaatt ttttgcaact cctcccgtgt cagccctttc tctaattgcg
    39601 acacgacgct cataatttgc gccattaccg aggcatcact ttctccataa cgcggatacg
    39661 gcgtgcattc gccggtgcct ttaataccct cttcttccag ttcaaccacc accacgcgcg
    39721 cttcactgcg acttccccgg gcaatcacaa acggggtatg taagggccag gcttcctcaa
    39781 ataccttaac ggttctcatc tttactcctt gttgtcgcgg tggtctgcgg attaagcgca
    39841 aatagcgttt gctgtgttat tgacagttag cataaactag gtgtgacgtt aactatatgt
    39901 aaacaggaaa gataatcatg tcacaaaccg ttcatttcca gggcaacccg gttacagtcg
    39961 ccaattccat cccgcaggcg ggtagcaaag cgcagacttt tactctcgta gcaaaagatc
    40021 tgtctgacgt caccctcggt cagtttgcgg gtaaacgcaa agtgctgaac attttcccga
    40081 gtattgatac cggagtttgc gccgcatcag tacgtaagtt taaccaactg gcaaccgaga
    40141 tcgacaacac cgttgtgctg tgtatttctg ccgatctgcc gttcgcccag tctcgtttct
    40201 gcggcgcaga aggtctgaac aacgttatca ccctctccac tttccgtaac gctgaattcc
    40261 tgcaagccta cggtgtggca attgctgatg gcccactgaa aggtctggca gcgcgtgccg
    40321 ttgtggttat tgacgaaaat gacaatgtga ttttcagcca gctggtggat gaaatcacca
    40381 ccgagccgga ttacgaagca gctctggctg tactgaaagc ataatttaat atgcctgatg
    40441 gtgttgcacc atcaggcata ttcgcgctta ctcttcgttc ttcttctgac tcagaccata
    40501 ttcccgcaac ttattggcaa tcgcggtatg tgaaacgccg agacgttttg ccagtttgcg
    40561 cgtgctggga taattgcgat aaagctgggt taataccgag cgttcaaaac ggctggtgat
    40621 ttcgtccagc gaaccttcca tcgcatcttc gcccacggct accgttgcgg cgtcataatc
    40681 cggcaacaaa atatcctgtg gacgcagctc ataaccgtcc agttgtgtca gtgcgcgata
    40741 gatagcgttc tttaactgcc gcacatttcc cggccacgca taacgcgtaa gtacagtatt
    40801 caggtcagcg gccagtttcg gacgcggcac gccctgctcg tcggcaaagc gggcgacgaa
    40861 cagctcagtt aacggcatga tgtcctgcgg acagtcacgt agcggcggca gattgagcgt
    40921 caacacgttc agacgataat agagatcttc acggaacatg cctttttgca ccagttcgac
    40981 cagattcttc tgcgtagcgc aaatcacccg cacatcgaca tgcacctcat ggtcttcgcc
    41041 aacccgacgg aaagtgccat cattaaggaa acgcagtaat ttcgcctgca tccgtggtga
    41101 catttcccct atttcatcca acagcaccga accaccgttc gcctgctcaa agaatccttt
    41161 cttcccttcc ggagcatgac caaacagttc actctcgacc gcatcttccg gtatagacgc
    41221 acagttcagc gccaggtaag gtttgcccgc tctggggctt gcctgatggc aggcgtaggc
    41281 aaagagatct ttacctgtac ctgtgtcacc cgtaatcagc agcggcgcgc ttagcatcgc
    41341 cagtttctgc gcctgttcga caacatgctt cattttcggg ctgacggcga caatttgact
    41401 gaaggcgctg acgtcctggg cggcgacatt ttgcaactgg cggcccatac gaatcgttga
    41461 tcgcaacatc accaccgcac cggtcaggac gtgttgatca ttttcatcct gaagataaac
    41521 aggcgtaatc tccatcagga aattctgccc attaataacg acatgctcgt tatgggaatc
    41581 ttgcggttcg ctttccagcc aacgtaaaaa attaaagccg ttaatcaatt gtgcggcggt
    41641 atggttgcgc aggcgatcca atttttgcgc aaaaagctga cagctcgccg ggttcgccat
    41701 atccactttg cttttcatat cgacagagag cacaggttcg ggcaacgcct ccagtaacgc
    41761 gctcaacgcc agatgctcac gttcggaagg catccacggg acagtacgca catcggtaac
    41821 acctgcaata cggcgtattt cggccatcag actgctgaaa ctctcaaact ccagttcagc
    41881 aaaattgagg tagattcgcc caatgggatc aatctcaata ccgcgtaaat caatgcctct
    41941 tagcacgagt agatcgagta attcgcgggt cagaccgagt cggtcttcac aaaagacttc
    42001 cagacgcatg ggaaccttca cctgaaaaaa gaacaattaa tatgatgata tgacactatt
    42061 tggatagcag gaaggtttct gtcaacaatc attgacacaa agacggaaaa acgggcactt
    42121 cggcgtaaag atatccggtc agcacccgat attgcattat ttttcgctgg gcgttttgcc
    42181 tttttgcagc gtttctttca cctgaccgat aagctgacga cggaaatccc cgaggcgagg
    42241 tttgtcatcg tcaatccacg gcagcgggcg gcaaagctcc atagctttaa tcccgagtcg
    42301 tgccgtcaga agtccagcac caattccctg agctgcgcgg gtagacaaac gagcagcgag
    42361 atcttgcgac atccagtcca tccccacttc gcgcaccagt tcgctggctc cggcaaaagc
    42421 gatattcagc aataccagct taaacagacg caaacggctg taatacccca gttcaatgcc
    42481 atacagcgtg gcgatgcgat taattaaacg cagattgcgc caggcgataa acgccatatc
    42541 gaccaacgcc agcgggctga ccgcaatcat caacgttgat tccgccgccg aacggctgat
    42601 ttcgcgccgc gcctgggcat ctaaaactgg ctggaccaaa tgcgcataca aactgaccac
    42661 ttcacggtcg ttttgcgttt catggattga ggcataccag cgttgcagcg ctggatgaga
    42721 ctgatcaata cccgcctgct gcgccagttt ttcgcaaaat gcgcggcctt tgcccgtgcc
    42781 gtggctgtgc aacaaatcgc gcgcttcgtc gcgttcatgg gcgcgctgtc gcaagcgcca
    42841 taagcgccgc cactctgtta ccacagtacc tacgccagcg ccgataatca atgccccagc
    42901 ggcacatcca cccagcgcca cccagtcctg agtttgccag gcattcattg tccactgtac
    42961 accctgcccg acaacgcttg cgccaaacag agccagcccg cccatcacca ttttgcgcca
    43021 caggctgcgt ttcggacgta acgctgcatc cattaccgct tcaacttgcc cctcttcttc
    43081 aggcgcttca tcgagcgtgg ccggggcaaa attttgcgcc tgattttcgt caaaggtctg
    43141 ctgcgccctg aattttggat tctgatcgac ctccagcgga ccgtcgaaat caatacgtgg
    43201 ttttaacggt tcggtcatcg caatttatct cctattaaaa attcaagcgc ggcatcaaga
    43261 cgaatatgcg gcagcggttt gtcgacatcc atcacctgcg ggcgaaacgc ttcaaactgg
    43321 aacccttgct tgtcccagaa cgcctgaccg ggcaaacgcg caggaacttc accgggataa
    43381 acggtgagtg gcgcaccatc gctgagccgg ttaccgcgca atgccggaat tttctcgccg
    43441 ttgacgtcaa taatgccgct ggtggtcgcc tgcaccgagg ccagccccag gcaatccata
    43501 ctaatccctt caaacgccgc attttgccag gcatcctgaa tcagttgttg cagtaatgaa
    43561 accatattgg cgtgctgatc gatggtcaca tggtccgctt tagtggcagc aaacaatagc
    43621 ttatcgataa ccggcgaaaa caaacgccgg aacaaggtac gctgcccgta gtggaaactt
    43681 tgcatcagct gcgtcagtgc cagacgcata tcattaaatg cctgtggccc actgttgaga
    43741 ggttgcaggc aatcaaccag cacaatctgg cggtcaaagc gcagaaaatg attcttatag
    43801 aaccccttca ccaccttctc gcagtaataa ttaaaccgct cgcgcagcat tccggcattg
    43861 gtgtgcttat cggcctgcgc cagtttggac tcgccccagg catcgacatc cggccacggg
    43921 aagaattgca gcgcgggcgc acctgccata tctcccggca agacaaagcg cccaggctga
    43981 ataaagtgca gcccctgctg tttacagtgg tggagataat cggtccacgc ggcggcaatg
    44041 tctgccagcc ggttttcgtc ggcaggcgct agcgggtcca gcccttcgca catcattcgc
    44101 catttgaccg accattcgcc gcgctgacca ttgagtaagc ccgtcatctg gcgtgaccag
    44161 cttaaatagt cctgcgccag catcggcagg tcgagcaacc attcgccggg ataatccaca
    44221 atctccagat acagcgtgga ggtgtccttg aagtggcgta gcagcgaatc gttcgattta
    44281 aaacgtagcg ccaggcggat ttcactgacg ccgcgcgttg gcgtcggcca ggcgggagga
    44341 tcgccatata actgcgccag tccttcatca tatgtgaagc gcggaatgcc aaagtcacgc
    44401 tgaggaatgc gttttacgcc cagcaggcgc tcttcacgca ccgcgcttaa cagcggcaag
    44461 cgtgctccgg cgtgaatatt gagcaactga ttgaccatcg cagtgataaa cgttgttttg
    44521 ccgctgcggc ttagtccggt tacggcgagg cgcagatgtc tgtcgacacc ccgattcacc
    44581 agcgcattaa gttcattttt aagtcgcttc attgctgtcc tgtgctgctc tgaagaccag
    44641 aaaaaaatca ttcgtaagga tatgaatgtg ggggccaggc cattgattat caactgcccg
    44701 tgttgtcatc gacgggcgaa ctccataaga tgtgcagcat tcacgttcgg acggagttcc
    44761 tgacctatgt cccctactat ttatgatatt gccagggttg caggcgtatc aaaatccacc
    44821 gtatcacgcg tgctgaataa gcaaactaat atctccccgg aagcgcgcga aaaagtgtta
    44881 cgggccattg aagaattaca gtatcagcca aacaagctgg cccgcgcgct gacctcttcg
    44941 ggttttgatg ccattatggt gatttctacc cgttcgacca aaactacggc gggtaatccg
    45001 tttttctctg aagttttgca tgccatcacc gccaaagctg aagaggaagg tttcgacgtg
    45061 atattgcaga cgtcgcacaa tccggcagaa gacttacaaa aatgtgaaag caaaattaag
    45121 cagaaaatga ttaaaggcat tattatgcta agttcgccag cggatgagtc attttttgcc
    45181 caacttgata aatacgatat tcctgtcgtg gtgattggca aagttgaagg tcaatatgcc
    45241 catgtttatt ctgtcgatac cgataatttt ggcgacagca ttgcgttgac cgatgcatta
    45301 attgaaagtg ggcatcaaaa tattgcctgc ctgcatgctc cgcttgatgt ccatgtttca
    45361 gtggatcggg taaatggtta taagcagagc ctggctgcgc ataatattgc agtgcgtgat
    45421 gaatggattg ttgacggcgg ttatacccat gaaacagcac tgcaagccgc gcgggaatta
    45481 ttaagccagt caccgttgcc tgaggcagtg tttgctactg acagcctgaa attaatgagt
    45541 atttatcgtg cggcagcaga gaaaaatatt gctattccgc agcagttagc ggtggtgggt
    45601 tatagtaatg aaacgctgtc gtttatttta acgcctgcgc caggcggtat tgatatccca
    45661 acacaggagt taggtcaaca aagctgtgag ttattattcc gcttaatttc tggaaaaccg
    45721 tcaccacaga atattaccgt tgccacgcat atgacgctga aataaatacc agctaccttg
    45781 cctgaatgcc ggatgcgatg ctagcgcatc ttatccggcc tacatttata gttcggataa
    45841 agtactcgtg ccgcatccgg caatttagcc cattatcaga acgagtaatt tacgccgaca
    45901 cctgcataat ggaatttatc gctgtcgcct tcgtcgtgat cctgccactc aaacgcgtat
    45961 tccagcgaaa cggaaagccc gttctggaaa tcataaccgt aaaataaacc tacacggtta
    46021 aaatcatggc cttcacgttc aatatcatcc tgccagtccc agttactcca gcgatccagc
    46081 ccaatgcgcg tatacggcgt caccgagtgg ttgccgagcg tcagcggcaa ataggcgcga
    46141 atttcttgcg tagaaaactc accgttattg cggctgtcgt ccatattaaa gccgcgctcg
    46201 agataatagt tcactcgcaa ggcaaccgtt tcgttgaagg tatattgcag gcctgtttcc
    46261 gtttcgactc gggtatcagc gtaaccggtc gtgttcagat cgttggcaaa tttatacatc
    46321 gacaaccaac cgttgaaacg taaatcgtca gtcagtttca catcccagtc tggcgcgatt
    46381 ttccagcgct gcatattcgc agtgtcttta cccggttcat caacgtagtg ataaccataa
    46441 ttacggaaac cgccggtcag gccgaaactg aaatcatcgt tttcgaggaa ctgataatgc
    46501 acctccagct ccgggcgatc aaaccacgtt ccacgtttac ccgcgctata atctaccggc
    46561 ccttcctgat aataggccag agcaattctc cacggcccgt tggcggcatt aaaatagact
    46621 gaaggctccg ccagcccatc catatcttcg ccataaccct cgacgttttc tatttcgtac
    46681 atcgcgccga tattaaagtg ccagtcgttc ctttcctcgg cctgtgcgca ggccattccc
    46741 gcacacatca ccagtgcggt acagggtaat aactttttca ttattgttcc ttgtattatt
    46801 ctgggggaat gccttccccc tgtatttagc gaattgctat ttccgtttct gcatcaaaga
    46861 aatgacattt cgtcatatca aaatgaatag tgatattttc tcctgcatga taatcattta
    46921 acgcaccagc acggaccact aactcgtgcc ccccaaccgt ggtgtagagc ataaattccg
    46981 caccggttaa ttctgccacg ctaattttgg cggaaatgtt attttcctct tgcgcgtccg
    47041 gatgaatatc ttccggacgt attcccatca cgatgggctt atgcaaactt ccctgtgttt
    47101 tcagaaccgc taatttctct tcgggaatgg ttaatttaag cgtttccgta acgaatttat
    47161 cgccatcgat cgtgccacga ataaaattca tcgccggtga tccaataaat ccggcaacaa
    47221 acatattcgc tggttggtta taaaccgttt tcggcgcacc aacttgctga acaatcccat
    47281 ccttcataat cacaatccgc gtcgccatgg tcatcgcttc ggtctgatcg tgggtcacgt
    47341 agatcatggt ggtattcagc ttctggtgta gcttgctgat ctctgcgcgc atttgcacgc
    47401 gcagcttggc atcaaggtta gagagcggtt catccattaa aaacacgccc gcttcgcgca
    47461 caatcgcccg cccgagcgcc acacgctggc gttgcccgcc ggaaagcgcg cccggcttgc
    47521 gtttcaggta ctcacgcagg ccgagaattt gcgccgccca gttcacccgc tcatcaatca
    47581 cctctttggc gattttttgc atcttcaggc caaacgccat gttgtcgtaa accgtcatat
    47641 gcggatacaa cgcgtagttc tggaacacca tcgctatatt gcgtgctttg gctggaacgt
    47701 cattcattcg tttgccgtcg atcaacagat cgccgccgct gatctcctca agcccggcaa
    47761 tcatgcgcag ggtggtcgac ttaccgcagc ccgacgggcc gacaaacacg atgaactctt
    47821 tatcggcaat ttccaggttg aagtccttca ccacatgcac ctggttatcg tagatttttt
    47881 gaatatgttg taacgaaagc tgagccatgt tgattccttt gctatacgtt ttgccagaag
    47941 gccgataacc gcgaccaggt cagagagtcc gttgaaggca acagtaattg cgccccggtt
    48001 aagcccgcgc cgatccccac cgagcgcata ccgctggcgt taatggcgtc aatgcccgcc
    48061 tgcgcatctt caatgccgat acatgcctgc ggcggcacgc ccagcccggc acaggcggcg
    48121 agaaagattt ccgggtccgg tttcgagttt ttaagttggg aagcatccgc gcagaaggtg
    48181 aaaaactcgc gcagctccag cgccgctaaa atcgtcggcg cattcaggga gacagaagcc
    48241 agcccaaccg ggatctgctg tgcacggaga tctgccagca aagagcgaat gccgggtaga
    48301 acagcgctga ccgtcaactc gcgcagtgag tggacataga gcagattttt gcgatacgcc
    48361 agttgcgccc tctcctgcga gttaaagtcg ccctctttgc ccccgtgttg cagaatgcgc
    48421 cgcagagact catcgcggct gatccctttt agggattcgt taaactgcgc atcaatgctg
    48481 atgccaattt cagcggcaat ctgctgccac gcctggaaat gcagatgcgc ggtatcggtg
    48541 attacaccat ccagatcgaa aattacccct tgcagtttca ttcatcctcc tgatgtgtgg
    48601 tagcggtccc attgaagggc aaaataaaat cacccaaaca gaaaacagat tcttcagcca
    48661 cggatataag ctgaccgttc aaacgcagtg aaacgggcgc agaagttcga atcgcaatac
    48721 gctgcgcgtc aagagtgacc tgtaattcgc agccctgcca gaacagaggg aaagacaact
    48781 gttgccactg ctcaggtaac gccggattga gatgcaattc accgtcacgc acgctcaccc
    48841 cggcaaaacc ctgaatcgcc cccagccaga tagcgccagt tgcggcagca tggataccat
    48901 catcacaact atgcggatca gcaccaagat cgatttcagt cccctcgcgc cagaactgat
    48961 aactttgggt cagcaggcca cagcgtgcgg caacaatgcc gtggattgct ttacttaatg
    49021 acgagtcgtg aatagtgcgc ggttcataaa attgcagatt ggcaagacac gatgccgctg
    49081 agaactgctc cggcagcatg taattgagca tcaccacatc agcttgtttg aggatttgca
    49141 tctcgttcac ttctgcgcgt gaataatcca gcagaatggt ttgcttcccc gccgccgctt
    49201 tgtatttcgc cagattaatc gccggcttag ccataaacga atcatcctgc ggcaaaacgc
    49261 cgtcgggctg aatttctggc agccgcagtt ctttaaggaa catttcggcg cgatggataa
    49321 acgcatcgtc gctacagcca aactggcggg caatactcag cgcctgctgg acgttgtaat
    49381 acgccatata gctggtgaag gcgttattat tgacatgttc ggtatattcg tcaggcccaa
    49441 taacatcatg aatttccaga cggtcgttaa ccctcaccgc gcggctaatc cagaactttg
    49501 cagtttccag aagtagcgcc atgccttcat gcgcaatgaa actttcatcc cccgtggtct
    49561 gccagtattg aataaccgcc caggcgatat cggccaccag atgatgttcc gcctgcgccg
    49621 aggccacttt ttgccgcagc ccggtgcgaa tgttaatggc ggcaaattcc ggcgtctctt
    49681 cttcgccgct gcgcgcgctt tcccacggaa atagcgcgcc ctgccagccg ttgcgtcgcg
    49741 ctttctcctg cgcgcctggc aagttgtgcc agcgataacg cagtaaactt cgggcaaccg
    49801 tcggatcgct aaacagatga aacggtaaca aaaatacttc tgtatcccag aaaacgtggc
    49861 ctttgtagcc ttcgccggtt aagccttttg ccgcaatgct gctgcgctcg tcgtgggcag
    49921 gcgtcatgat gcgcagatga taaagcgcat aatctaacgc ttgctgatcg tgcgcttcgc
    49981 cgccatttac cgtgatacga cgtttctgcc accattgacg ccagttttct gttgatactg
    50041 caagaagttg gtcgtaactc tgctgcgcgc acatttcaag ctggcgaagc gacgcgctgc
    50101 cccactcgtc taaaacggct tgcctgtcat cccgccagtc gatccacacc agtttttgca
    50161 acgtcactgt ctcgcctgca tgaagctgcg cactggtatg ttgctgcaaa cggcgctctt
    50221 tggcggtata gcattgctgc acatcaccgc tcaccataca gcaacagctg atggccacat
    50281 cactgcgtcc atcctgggtg gtgtagatcc cctgcatcag atgctgacca aacacccgca
    50341 cctgggtttc gtcgagatgt tggcgaccgt ggttggtttg cgtggcgtcg atacctgttg
    50401 aaatcagcac tgacgcgtcg gcgtccagtg gcgtaatagt gatttccagc acaatgagcg
    50461 gcagttggtc tgccgaaaca aagcgacggc tggcgatggt gtaacctgtg ccgttgctgg
    50521 tacgccagac aacgctacgg cgtaattctc cactggcaaa gtcaagttca cgctgccagg
    50581 cttcgcggga taacgagaaa acctcaccat ttatggcaat ctccatcccc aagatatcag
    50641 gcaggttcac cagttcgttg atttcacctt ttcccgcccg atgatacagc cccgccagat
    50701 acatccctcg cgtctggcgc gtgtaatctt cttcatggct ggcgcgaagc ccaagatagc
    50761 cgttcccctg cgccatcagc gatgcatact tgttcagggt atgctggctg aaatggggtt
    50821 ctgataacgt tactggcctg gtcataattc cacacgcgtc cctgtttctg cggattgata
    50881 caacgccgcc accagttgct ggatgatgta cccctgctcg gcgtcggcta tcatcacggg
    50941 cttgccctgt acgtgattga taaaggcttc catgctgcgc aaatggcggt tgtcgtctgc
    51001 cagttcccgt tgcatcagcg tcattaattc accgttgtta tcggtgtaga tatgtgctgg
    51061 aaacagcgtc gcaccggctt tatcaccaca aaagctgacg ttcataatcg actgttcgcg
    51121 gatgttgagt gcaaatgacg tttccagcca cagaatgccg ccgttatgaa attcaatggt
    51181 gccaaataac gaatcttcga cgctgtaagt tgccggatcc cactcgccaa attgaccgca
    51241 gctcttttgc gtgccgatct tttgaaagct atgcgcattc acgcttttca ccgccggaaa
    51301 gcccagcaca tacatcgccg catccagcat atgaatgccg atgtcgataa gcgggccacc
    51361 accctgcagt tctttattgg taaagacacc ccagccggga acgccgcagc gacgcagggc
    51421 gcgggcggtg gtaacgtaaa tctctcccaa aacgccgttg gtcacctgtt cacgcagctg
    51481 ttgcgtatcg agcgcaaaac ggtggtgaaa gtcgtaggcc agcaccttgc ccagtttgcg
    51541 cgcggtatcg cacatttccc gcgcctgttc tggcgtcatg gcgggcggtt tttcgcacat
    51601 cacatggcac cccgcttcca gtgccatcag ggtatgttcg taatgaaaac ggttaggtga
    51661 gcagacgcta accacatcag gtttcaccgc cagcagcatg gcctgcggat cgtcccacac
    51721 ggatgcatta ccgtatttat ctgccagcgc ctgcgcctgg gaaaggcggc tgtcacagac
    51781 agccaccagt tccagatcgt tgcgggtgca gtagtacgaa gcatgaacct tatccgccac
    51841 ctggcctgcg cctattatcg cgacccgcag cggagagctt gtcattgcac ttttcacaaa
    51901 gacctcttag caggtacgca accaggccaa cgaatcacgg tacgcctggg caggatcttc
    51961 cgcccggata cgcccttcgt acactacata gccctgatag ttatccgcgc gcaactgttc
    52021 aaacagcgcg tggaaatcca gggtgccgct gcccggctgg tagcgatggt tatccgcaat
    52081 atgcacatga ccgagcaggt cgcggttgtc atgcagcgcc tgcgccaggt tatcttcttc
    52141 gatattcatg tgatagaaat cgccgataat ctgtacatgt ttaagatcgt tttcgacgat
    52201 gtaacggcgg gcatcggcga gggtgttgat catatgatcc tgatagcggt ttaacggttc
    52261 gagatacacc acggttccgg tacgcgcggc gacctgttcc agtacgtgca gggaatcact
    52321 caccattttg cggtcgccgt ccaggctacg cggcgaggtc atcggcggta agcggaaggt
    52381 aaacatgccc cacgctgccg gaacgacgat acctttaccc cccacttctg ccagcgcttc
    52441 gagaatgcgt tcgatctgct ttaagccatt aagacgacgc tcttcgataa agtcgccaat
    52501 ccaaccgtca tagccaccgc aggcggtggt caccggtaaa ccggtttctt tgattgctgc
    52561 tttgacttct tcgagattgt tgaccagcag tttgccgtca atctcaaaac catcgaagcc
    52621 catctctttg atataacgaa atttctccag aatgttttcc ggaaagaatg cctgattctg
    52681 tgtgcctatt ttcatttttt cattcctttg aattaaaacg taacgcccat tttgatgctc
    52741 tgttccggat gctgatcgac atactgcatg tagctttccg ggctcttggc aaaggtcact
    52801 accgggtcga ttaaatcttc gcaattgaga taaccgttca tcagcagttc ccagcaggtt
    52861 tcttcaatac gcttacggct ccagcgcgga taatccgggt tcggttcgct gcacgcacgg
    52921 gagaaaacaa ttttggcgtt attgaaatgc gcttcgcgtc cgaggttaaa accttcagca
    52981 aatggtttgg caaacgcgac ataagagatg gtgccgccat aagcaaggcc acgcagcgcc
    53041 gattgcagcg cgtcggcgta accgctggtt tcgataatca catcggcacc ctgcttgccg
    53101 gtcagcgttt tgatctcttt tcctacgtca gtgccaatgg ggttaaggca gaaatcagca
    53161 ccgtggcgac gggcaatatc acagcgatag gcgataggat cgacgccaat caccaccgac
    53221 gcgccagcgc gtttcgccag ttggatggct atttgaccaa tcgcgccaag ccctaccacc
    53281 accacaaaat cacccacgcg cacgttggca tcgcgcacgc cgctcatggc aaactgcgcc
    53341 gggtcgtaac aaacggcgtt tttccacgag ctgccttccg gcattttgcg cagcttgtag
    53401 ttattcaccg cgttaatgat gaccgtctcg gagagcgggc cgtagccgca tacgctgtcg
    53461 cccaccgcgt agtcggtaac gtcgctgccg cactcgataa tgtcgccaac caccatgttg
    53521 ccaagctgga atttgccaaa ctcaatgccg cgcggcgcat ctgccggacg cggagtgaac
    53581 atctgccatt cgccgttaaa gtcttcatcg ataaacgggc tggcggcgcg gaagtcgacc
    53641 acttccgttc cgtgtttcgg tgcgccgaaa cgcacgcgga ttttcacttc attggctaaa
    53701 atcgcccgat cttcatactc aaccagcgca gcaacacgcg gtgctgtggc tactaacttt
    53761 ttcatttaaa actccttgta aagaaactgg ccgctttagc ccttcacgcc accggcggtc
    53821 aaaccactct taataaaacg ttccgaaagc gcatacataa tcaccaccgg caatgcggtc
    53881 accagtgagg ccgccatcat ccgtccccag atgtaatctg gcgtactgaa cagcgcgttc
    53941 aggcccaccg gtaaggtgaa attgctggcg ctggagagga aaatcgacgc aaacagatag
    54001 tcgttccacg ccaccataaa gcagtagacg aacacggata tcagcccgga catcgccaac
    54061 ggcacggtga tgcggaagat aatttgcaga cggttgaggc catccatcat cgccgcttct
    54121 tcgatctcat cggggatggt gtcgaagtag cttttcagca taaacacggc ggtgggcaga
    54181 gtttgcgtca ccatggtgat gatcagcgcc atctcggtgt cgtaaatgcc cagcgcggtg
    54241 atgattttga acagcggcac caccagcaaa atgccagaga acatatacac cgtgtaaaag
    54301 ctggcattga tggtcatccg acctttaaag cgcaggcggg aaagcgcgta agccccaaga
    54361 atgccgagga ataccgccac cacggatgaa accaccgaca ccaccagact gttacggaag
    54421 tagtcgacaa acgggaaaat catcgggtta aaaatgtcga cgtaatgctc cagcgtccac
    54481 tgctgcggca gcagcgtagg atgcagtgag atcgcctctt tcgcgccctt gaacgaggtc
    54541 atcagcatca caaaaaatgg aaacagcgtg atgatgagaa acagcgccag cccgcagtaa
    54601 aaaccgatgc gactgagtgt gcgtttattt gttgccattg aggttcaccc gtttcctggt
    54661 cagcagaatg acagcgaaaa taatgatgaa gagcaccacc gagatcgccg ccgctttccc
    54721 taagtcatta aaggcaaagg cggttttgta gagatataca ccgagaatat cgaccttggt
    54781 cgtcagcaaa taaacatccg cgaacatgta gaacatccag atggtgcgca gggtcaccac
    54841 cgtcgccagg accggcataa tcgcgggcag cgtgacgata cgaaaccgtt gccaggcatt
    54901 agcgccatcc atctctgcag cttcgtacag cgatttgtcg atggtctgca aaatcgccag
    54961 aaacgagata aaggcatacg ggaagtagcg ccagatggcg aacagcacca ccagcacaaa
    55021 gctactgccc ggattatcga accacagcgg tgcctgctca tagagatgca gaagatcgac
    55081 gccgaggtag ttcacaatgc cgtagccgtt gttgaacatg tatttccagg caaacaccag
    55141 cgaaatggac ggcgttacgt aggagaggat caccagcgaa cgcgcggttt tgcgcagatg
    55201 gaactcgcgg ttgaaaaaca tcgccactgc cagcccgagc acggtgctgc ccgccaccac
    55261 cagcgcggta taccagaccg tcatccacag cgagtgccag aagccgggat cggagaggat
    55321 acgcacatag ttactcaccc caacaaaggt tgactcgatg ttgggattga gcggcagacg
    55381 taaaaaactg atttcgatat tcgacaccat tggccaggcc accagaccac ccagcagtaa
    55441 taagctgggc gcgagaagca gcagcgcaaa gggcatatcg gaacgacctg aaaaaagcct
    55501 gttcattgcg gattcctgtc ctgggtttag tgctgttcga tcagttcatc cagctttttc
    55561 tggctcgctt gcagcgtgcc agggagatcg gctttaccca cggtgacgtt atgcaccatg
    55621 gagctcacca ctccagaccc cgtcacatca cccatgcggg taaagttttt atcccctact
    55681 gcaccaaaga cctgaatatt tggcagttca ccgattagct gattcggtag ttcacccagc
    55741 gccttaataa cgtcgttgtc tttccaggtg gcggtagtga caaccgcttt attcaccggc
    55801 agcgcagcac ctggcgacat catcacccag tcggcaatgt tgtctgcctg ctccataaag
    55861 gtgacaaatt tttctgctgc ttccgtctct tcggtctttt gcccggcggt aatggtcagc
    55921 gaggtcaaca tgccgtagac cgcagagttt ttctcggttg gcaccacgaa accgacgttt
    55981 ttcgggtcgc cttctttaat cacagccaga aggatatagg tggagtaaat cgccatcggc
    56041 gcggtgccgt tcataaaggc gtctttcact tccatgatgt cgttagaacc cggcatagtg
    56101 ttggcagcaa ggtcgcggta ataggtcagt gcctgcatca tctctggtgt atcaagggtg
    56161 attttgcctt cggcgttaaa gacgttagcc tggttggata acgcaaactg ggagaaggat
    56221 tgttccgtca acacgctttc tgctgtaggc agcgcaatgc cgtatttttt attcgccggg
    56281 tcattcagtt tctgtgcaac gtccagcagc tgttgccagt ttttcggctc ctcaagcccc
    56341 gcttttgcca gcacatcttt gcgataccag ataccgccaa tccaggcgct gacaggaaca
    56401 ccggtccatg cgctaccatc ttcggtacgc acaatacgca gtacgccatc gtaaaacgcg
    56461 ccttcaccaa cgttactgat gactgtggca accgctttgc gatcgataag ctgctctttg
    56521 tccatcactt tggcgtagtc atggctggtt tcgatcactt ccggcagcga accgctacgt
    56581 gaaagagtaa tgactttagt gttataggca tcttcttcca cgggcacttg cttaacggtg
    56641 atgccagggt tttctttttc aaaacgggca atcaatttac tgataacggc ctggcgctcc
    56701 tgctccaccg aagaatgcat aaattcgatg gatacattcg ttttattttc ttctttacag
    56761 cctgaaatca gggcgcagga aaccagtgct gataacagca cgatttttga tttaatcatg
    56821 agatgttcct ttttatttaa tccacataac ctgccagggg cgcagcgtta tttcattacc
    56881 caatatatca acttcactaa tcagatcccg accatgcaga ttagtaatat ttacatgctg
    56941 aatattttta ctgacattaa acaatccagt cagacaatta ccatcagcgt tacttctttg
    57001 aatacgcatt acggatgaat taatcgtatc gatggtaaaa ttattatccg gatgaaactc
    57061 gttatggctg cgacgaagtg taattaaacg cgacaactca tgatataccg catgccttaa
    57121 tgtagcttca tcgttcagtt ctcgggttat ctctttactg tgatattttt tacggttaat
    57181 cgcacggtta tatccgagtt tttcgacacc tgcgtaatca ttacgcgagc caagaatact
    57241 ttgaatatat atcgctggca caccggggaa acttaacaaa atcgcatggg cgagaataaa
    57301 cctggcgcaa cgttcttcat cgctactctc acggcggctt aacgcatcca tataggtcac
    57361 atttatttca tacggactgc gtgtaccgtc gggattattt ttccagttta ctaatgcacc
    57421 ttcctgctgt aacgcctcga ccagctctaa tatttcgctt tcaggcaaca agccccgtag
    57481 cgggtttagc ccgatgccat cgtgagaggc gaggaagtta aaccaggtgg tgttgctgga
    57541 aggtagtgtc aggttttgcg cccacgcaca aagcgcctca acgttctgtt tttgcaccgc
    57601 atgcagcacc agtggcggca gcgagaactg gtacaccata tgtgcttcgt catcgcctgc
    57661 gccaaagtaa gcaatgttgt ctttatgcgg aacattggtc tcggtaatga tcactgtacc
    57721 tggcgcaacg ttatcaataa tcgaccgtaa cagtttgata atcagatgtg ttttttccag
    57781 atggatgcag ctttttcccg gctctttcca cataaagcca acggcatcca ggcggacata
    57841 ctcagcacct ttcgcaaggt aacagagtaa aacatccacc atcgccagca acacttcagg
    57901 gctacggtaa ttcaggtcaa tttgatcgtc actaaaggtg gtccataaat ggcgcgttga
    57961 atgatcgcgc atctggaatg gcgttaataa cggtaacgca cgcgggcgag tgacggcgct
    58021 gagatcggtt tgcgggtcaa cggcaataaa aaaatcttca aaacctggat gctgttgtaa
    58081 atagttttta aaccattcac tttttgccga catatggttg cagacaaaat caaacattaa
    58141 atgactgcat tcaccgagtt gctgaatatc ctgccactcc cccgcttcac tggcgacctg
    58201 atgataatca attaccgaaa agccatcatc agatgaccat ggataaaacg gcaacaaatg
    58261 aacatgtgaa aaaatgcttt gcagccattg atggtaaaac tgattaaatg tgggtaatgg
    58321 ttttaaatca ttgctgtgaa attgatcggc ataggtaatt aacacgacat cactttcatc
    58381 ccagtgtttt ttacgtcgct gtgtaattaa tcgtttcgca ctctcaagac gcgttacaag
    58441 tttctgtaaa tgagttgcgg taaatgttcc accgtagatt tcgtccaggt aatccgtaat
    58501 tttctgtttc atgttgcctt tccgtggtag cggtcccatg aaacgagaga ctactccgca
    58561 gaaaataaac tgtcaattga gcacaagggt tttagtcacg caggaaatca ttttttacca
    58621 gggaaaaagc gtatttgtga gctgacgcaa ataatctatg gggatgtaaa taaggtgtga
    58681 cagaaaaaaa aacggcgcat aagcgccgct catggtgaat tcttttaacc tttgaccttc
    58741 ggcattgcga tgtctttcag gccaccggcg ttctcaacgt gggtatatcc catctcgcta
    58801 aggatctctt ttgcttgccc tgactggcgt ccggcattgc aatacacttt cacggtgtcg
    58861 tttttatccg gaacggcggt ggcaatgcgc tctttcactt ccttcagggg aatattgatg
    58921 gccccctgaa cgtgctcttg ctgatactgc tctggaacac gaacatcgat ccagtgttca
    58981 gcggcgaaaa cgggcagtga aaacaccagt gccagagcaa gtaagccttt tttaaacatg
    59041 taagcgtcct tctatggatg aaaattgcca tccattatac gcctgagatt taacaatttt
    59101 tgcgaaactc ccctcacctt ttataacgct gtgccagttt attagcagcc cgacttaaca
    59161 gcggttccag cgccacagcc agcaacattt tcagcggtcg gcgagcaact gattttatcg
    59221 cccagcccgc cacacccgcc gggccatagc gcagtgcggt aagaagtacc agcttgcctg
    59281 ctaatttgaa accaggcttt accttttgcc cggcctgttg ccagcgagta ttcataactt
    59341 tcctcacagt tgacggaaac ggctacgtaa cgtgaaagta tcggaagtga cataacgttc
    59401 catctcgcgt aaacgcgttt cacttgccgc cagttcacgg tcgacttcat ccagcaattc
    59461 gctgctggaa ggtagctgct caccaaaggc catgttgtcc ggcattggat caagcgcaaa
    59521 tgacaaaatg atgtaagcaa ccagggtaaa cagcgccaga ccgaagaaaa tcgacagcac
    59581 caccaggata cgcaccagtt ttgccggtac atcaaaatag ttggcaatcc cggcgcagac
    59641 gccgcggacc atgccctgct gtggaatacg ccataatttt ttattgagat taatgcccgc
    59701 cattagcgat ccctccagtt cggatgttct gcatcaagaa tagattccag cgcctgaata
    59761 cgttcgcgca tccgttttgc ttcatcagcc agttgcgcta atcgctgctg ctcactttgc
    59821 gacaattcac tgcgaccaga acgattgctg taatgcagcc ataaccagat cggtaaaaca
    59881 aacagcacaa aaatggttaa cggaatagcc agaaatagcg cgctcataag tactccttag
    59941 acgatgagcg gcggcgcgtt cggacgccgc ctggatgtta ttattgattg tcttgcttca
    60001 ttttggcttt taattgtgcc agttgttcgc tgattgcatc atcggctttc agttcggcaa
    60061 actgatcgtc cagcgatttt tgtttaccga agctgtggct ttctgcttcc gcttccatct
    60121 ggtcaatacg acgttcgaaa gattcgaaac gagccattgc ttcatccagt ttgccactgt
    60181 ccagctgacg acgcacatcg cgcgacgagt ttgccgcctg atgacgtaac atcaatgcct
    60241 gctggcgagc gcgtgtttcg ctcaatttgt tttccagctc accgatctct ttcttcatgc
    60301 gtgccagcgt gtcgtccacc agcgtcactt catgttccag gctcttaatc agatcggtca
    60361 gtttctgttt ttcaattaac gctgcacgtg ccagatcctc tctctctttc agcagcgcca
    60421 gttcggcttt ttcctgccat tcaacttcac gcgccgacgc ttgttcaata cggcgagtca
    60481 gctgtttctt ttctgccaac gcgcgcgccg aagtagaacg tacttcaacc agtgtatctt
    60541 ccatctcctg gatcatcaga cgaaccagtt tctgtggatc ttccgctttc tctaacagag
    60601 cgttgatgtt ggcattcacg atgtcggcaa agcgagaaaa aatacccata atgttgtcct
    60661 cttgatttct gcgttcagga ttgtcctgct gaactgttaa tacaatttgc gtgccaattt
    60721 tttatctttt tgatttataa agatctgatt gaagaatcaa cagcaacatg ccaggatgag
    60781 ttagcgaatt acactaacaa gtggcgaatt tcatcatggc agaatacaaa gataatttac
    60841 ttggtgaggc gaacagcttt ctcgaagtgc tggaacaggt ttcgcatctc gcaccgctgg
    60901 acaaaccggt gctcatcatc ggcgaacgcg gcaccggtaa agagctgatt gccagccgcc
    60961 tgcattatct ctcctcccgt tggcaagggc cgtttatttc ccttaactgc gcggcgttaa
    61021 atgaaaatct gctggattcc gaactgtttg gtcacgaagc gggggcgttt accggtgcgc
    61081 aaaaacgtca tcctgggaga tttgaacgtg ccgacggcgg tacgctattt cttgatgaac
    61141 tcgctacggc accgatgatg gtgcaggaga aattattgcg cgtgattgag tacggtgaac
    61201 tggagcgcgt tggcggcagc cagccattgc aggtgaatgt gcggttggta tgcgcgacga
    61261 atgccgatct cccggcgatg gtcaatgaag gcacttttcg cgctgacctg ctcgaccgac
    61321 tggcttttga tgttgtacaa ctgccaccac tgcgcgagcg cgaaagcgac ataatgttga
    61381 tggcagaaca ctttgccatc cagatgtgtc gggaaatcaa gctgcctctg ttcccggggt
    61441 ttacggagcg cgccagagaa acattgctga attatcgttg gccgggaaat attcgtgaat
    61501 tgaaaaacgt ggtggaacgt tcagtgtatc gccacggcac cagcgattat ccgcttgatg
    61561 acatcattat tgatcccttt aaacggcgtc cgcctgaaga cgctatcgcc gtttcagaaa
    61621 ccacctcgct tccaacactg ccgctggatt tacgtgagtt tcagatgcag caggaaaaag
    61681 agttgctgca actcagtttg caacaaggga aatataacca gaagcgcgcg gctgaattac
    61741 tggggttaac ttatcatcag ttccgcgcgt tgttgaaaaa gcaccagatt tagcgaagtt
    61801 gagcaataca acttgcagga tgcggcgtga atgctttatt cggcatacat aatcaatacg
    61861 tcgtttgcag gcctgataag cgcagcgcat cagacattat tgcgttgggc tattaatcgc
    61921 tcagcgcatc ctgcaaaatt ttcattgccg catcgaattg cacatccggg atggtcagcg
    61981 gatacaggaa gcgaatcacg ttgccgtatg cgccacaggt cagcaggagc agcccctgcg
    62041 ccagcgcgcg ttgctggatt ttctgtgcaa tcgccgctga cggcttgccc gtttgcggat
    62101 cgttaaactc tgccgcaatc atcgacccca ggccgcgtac cgcagcaatg gccggaacgc
    62161 tttctttggc atcaatcaac gtgtttttga gacgctggcc cagttgattc gcgcgttcgc
    62221 agagtgattc tttgtcgata atattgagca ccgcgtgcgc ggcagccacc gccagcgggt
    62281 tcccggcgta ggtgccaccc aacccgcccg gcgcgggcgc gtccataata ttcgcgttac
    62341 cgaccacgcc cgaaagcggc atcccgcccg cgaggctttt cgccatcgtc attaagtccg
    62401 gcttatcggc gtaatgatcc atggcaaaca gtttaccggt acgcgcaaag ccgctttgca
    62461 cttcatcggc aatcatcaca ataccgtgct cgtcgcacag gcggcgaatg gcggcaacca
    62521 gctcttttgg cgcaacgttg aaaccgccct cgccctgcac cggttcgaaa ataatggccg
    62581 cgacctgctt cgcttcgatg tctgatttaa acaagcgttc gatggcgtcg agggagtcct
    62641 gtgttgaaat gccgtgtaaa tctgacggat aaggtacgtg atacaccgaa ccagggaacg
    62701 ggccgaagcc gattttgtac ggcgcaactt ttccggtcag cgccatggtc atatatgtac
    62761 gaccgtggaa gccaccgcta aacgcaatca cgccaggtcg tccggtatgg gcgcgagcaa
    62821 ttttcaccgc gttttccacc gcttccgcac cggtagtgaa gaatgcggtt ttagcctgcc
    62881 cgctcactgg ggcaagggcg ttaattttct ccgccagcgt gacgtagctt tcgtacggca
    62941 caatctgata cgccgtgtgg gtaaactgtt gcaattgctg ctccaccgcc gcgaccagat
    63001 cagggtggcg atgcccggta ttcagcaccg caatgcctgc ggcgaaatcg atgtattcgt
    63061 tgccctctac gtccttcagc gtagcgtttt ctgccgactg ggcgaagaag ttacacatca
    63121 cgccaacccc gcgtggggta gcagaaagac gacgctgatg gaattcattg ttgctcatgt
    63181 ttcacacctt ttgactcttc actgttaatc ggaaattaaa cgcccagacg atcgcgcagg
    63241 ctgtaataag ccgcgcccat cgcggtaaat ggcacgcgca gcgtgcgccc gccggggaac
    63301 gggtaatgcg gcagattggc gaaggcatcg aaacgttcgg cgtcgccgcg cagcagttcg
    63361 gcaatcagac gcccggcaag atgggtacag gtgacgccgt ggccgctgta gccctgcatg
    63421 taatagatgt tggtatcaag gcgaccgaac tgcggcatgc gcgacaaggt cagcaggaag
    63481 ttgcccgtcc agcggtaatc aattttcacg cccttcagct gcgggaaggt tttcagcagt
    63541 ttcggcacca caaggcgctc aacgtcatcc gggtcgcgcg cgccgtagac cacgccgccg
    63601 ccgtacagca ggcggttgtc ggcggtaaga cggtagtaat caagcagata gttacagtct
    63661 tccacacagt agtttttcgg gatcagcgaa cgggctaaat cttccgacag ccgttcggtg
    63721 gtgatcacct gcgtgccgca cggcatgctg cgtttcgcca gttccggctc tactttatcg
    63781 cccagatacg cattcccggc gacaatcaca tacttcgccg tcacctgacc tttggcagtt
    63841 cgcacaacgg ctggcgtggt gtgctggatc tgcgtcacgg cagaaagttc atacacgcgc
    63901 ccgccgttga ggcggatggc gtccgcttcg ccaatggcga ggtttagcgg atgaatatgc
    63961 ccaccgctgt gatccagcag cgcaccggta tagcgatcgc tggctacttc acggcgaatg
    64021 gcgttggcgt ccagcaattc cagctgttta ttgccgtagc gttcccagtt ctctttctgc
    64081 tcttcaagtg tggcgagctg tttatcattc atcgccacaa acaggccgcc ggggcggtag
    64141 tcgcagtcaa tctgataacg tttgatacgt tcgcggatga tctcaccacc ttcgaacatc
    64201 atgctgccga gcatacgggc ggtgtccatg ccgtagcttt tttcgatcac gtcgatgtcg
    64261 cggctgtagg agttcacaag ctgcccgcca ttgcgcccgc ttgcgccaaa gccgatgcgt
    64321 gaggcttcga gaaccactac gtcaaagccc gcttccgcca gatgcagcgc ggaagagagc
    64381 ccggtatagc cgccgccgac cacgcaaacg tcgcaggaaa tcgactcatt cagcgtgtcg
    64441 aatggcgcgt atttattcgc actggcggcg tagtaactgc ttgtatgttc ggtcatttca
    64501 ggcctccagg cttatccaga tggttttcag ttcggtgaat ttttcaaggg catgcaggga
    64561 tttgtcgcga ccgttgccgc tctgcttata gccgccaaac ggcacggtca tatcgccgtc
    64621 gttgtagtta ttgacgaaga cggaaccagc cttcaggcgg cggctcatgc ggtgcgcgcg
    64681 ggagaggtcg cgcgtccata ccgccgcgcc aaggccgtac tggctgtcgt tggcaagctg
    64741 tagcgcctgg tcttctgatg tgaaacgcgt gaccaccagc accggaccga aaatctcttc
    64801 gcggcttaag gacgcattcg ggtctacatc cacaaagatg gtcgggccga tggcggcagc
    64861 cagctcagcg ttacgaccat ccagcagcag ttgccctttg ctttcgcctt cccgaataaa
    64921 gctatggacc gagtcggcgt gggcgcagtc gattaaggtg cccatggtgg ttgcgggatc
    64981 aagtggatgg cccggctgcc agttttgcgc ctgctgtttt aacagggcta agaattcatc
    65041 ggcgatgctc tcttccagca acaaacgcgt tccggcgatg cacacctggc cctggttgta
    65101 gaagatgcct gcggcggtgg cgcttgccgc tttttgcaga tccggacaat cggcgaaaac
    65161 gaggttggcg cttttgccgc ccgcttccag ccagacgcgt ttcatgttgc tgtcgcccgc
    65221 atctttcagc agctgtttcc cggtacgggt tgaaccggta aaggcaatgg cgtcgatatc
    65281 gttatgacgc gacagcgcct gccccgcttc atgaccaaaa cccgtcacca cgttcaacac
    65341 accatccggc aagcctgctt ctttcgccag ccccgcgaga cgaatcgcac tgagcggtga
    65401 tttttcagac ggttttagaa tcacgctgtt tcccgccgcc agcgccgggc cgagtttcca
    65461 gcaagtcagc aacagcggga agttccacgg cacgatggcg gcaatcacgc cgaccggttc
    65521 acgcacgatc atcgccagct catggctact ggtggtcgcc acttcgccat acactttgtc
    65581 gatcgcttcg gcgtaccagc gaatggcgcg cgccgcgccg ggaatatcat cacgcagact
    65641 gtgacgaatc ggtttgccgg tgtcgagagt ttccagcagt gccagctctt cggcgtgggc
    65701 ttccattaaa tcggcgagtt tattcagtac cgctttacgt ttagccggag aagagagtga
    65761 ccagtcgccg cgttcaaata cgccgcgtgc tgcgctcacc gcacggtcga tatcgacgct
    65821 cttgccgcgg gcaattttcg ccagcggtgc ctgggtgacc ggatcaacgg tttcaaaggt
    65881 ttcattttcc gccgcagcag tatattcacc gttaataaat aagcggtttt caatggcgag
    65941 acttaacgct ttatcctgcc agtaagccag atgatgaaaa ttcattatga ctcctgtttc
    66001 acgtctatca gatatatgca gtttgtgaac gtcagggcgc agagatcccc gggccgtatg
    66061 cccgtttatt tctggcgaca ttctttatat acacttcatc cttcaagccg cctctgcctt
    66121 ggctgcgttc gctcccccga atcacttacc tgagtaagct catcgggatt cgctcacttg
    66181 ccgccttgat gcaacttgaa tgattttgtg tatagattgc cgggcgcatt gcgcttaccc
    66241 ggcttacaga acaaaaagat taaaacgtgg tgggcgtatg ggcgctgata attcggcaaa
    66301 tacctgccga cgtattactg aaactgtgcg ggatgccggt attaatggca taactttgcc
    66361 ccgcgacgag gtggtaatcc tgaccattaa tcgtcagaac aatttcacct tccagtactg
    66421 tgcctatttc ctcaccctga tgcttaattc tttccccagt ggttgtgccc ggctggtacg
    66481 tttcaaagat catcgccagc gtgcgattcg ggttaccatt atgaaccagc ttcattgaca
    66541 caccctgact gcccatctca attaagtcgt cctgattaat gacgacctgc ggctcatcag
    66601 gtttttccgg ctcggaaaag aattccgaga gtgacagacc atacaccttc agcagctttt
    66661 gcagcgtact gatggcaggg ctgactttat cttgttctat cgtactgata gcactgtgag
    66721 tcagcccgga gagttcggcg gcacgacgtt gtgaaagccc ctgctgctgg cggatttccg
    66781 acaagcgttt tcctggcgcc agtccctcat cactcatatt tgcatttcct taaactgtag
    66841 tggtcagagt cgctgttttt cagcgatatg gtgctgacaa gcggtgataa agccctcgaa
    66901 caatatacgc gaaagcgcgt actcgctact gttccattcc gggtgccact gtacgcccag
    66961 cgcaaaagga tgattgatga cgctaaccgc ctcaactaag ccatccggcg agcgagcttc
    67021 aacacgcaac cgtgggctaa cgaccttcgc cccttgccca tgcagagagt ttacccaaaa
    67081 gttgctacat tcaggtaaca acgcagacag taatcccccc tcttcaacct gaacttcatg
    67141 cgacggtgca tattgctgtt ccaccggcag ttcgggatct tcccgatgtt ccagcaattc
    67201 aggctgttcg cacagcttgc gatgcaacga accaccggtt gccaccacca gttcctgtaa
    67261 accccggcag atggcgaaaa tggggatgcg cctttcgagt gcggcattaa ttaacgccat
    67321 gctcagaaga tcacgcccgg gatcggcgtc aggctcatcg ccgttttcac catataggtg
    67381 cggctgcaca ttgctgggac taccaggaag ataaatgcca tcgagtttcg gcaaaagttg
    67441 ttcaagtaat gacggttccg ccagcgcatg tggtagcgca attggcaagc cgcctgcgtg
    67501 gatgatggca ttcaggtact tttcttgcag agtctgggtc gcatgatcct taagcctgtt
    67561 cctgcacatt acgacaccga taaccggatt gttcattata ttttccatgc tcaatctcac
    67621 aaagtggact aaattatcgc cattactgcg gtttaaatga cctttatgtt caatattttt
    67681 tcaatctagc agtgggtttt catttttgca aactcaattt aacatttgac aaacatttag
    67741 tttgcataca gattcgaatg gtggtcatta tattttacgc tttgataacg agcggaaaac
    67801 aaaccaaagg cgaagaatca tggaaaccaa tatcgttgaa gtagagaact ttgttcagca
    67861 gtcagaagag aggcggggta gcgcctttac gcaggaagtg aaacgctacc tggagcgcta
    67921 cccgaatacg caatatgttg atgttttact tactgatttg aatggttgct tccgtggaaa
    67981 acgtatccct gtttcaagcc tgaagaagtt ggagaaaggg tgttatttcc cggcctcggt
    68041 gtttgcaatg gatattctgg gcaacgtagt agaagaagcg ggtctgggtc aggaaatggg
    68101 cgagccggat cgtacttgtg ttcctgttct cggttcctta accccttctg ccgccgatcc
    68161 agagtttatc ggtcagatgc tcctgaccat ggtcgatgaa gatggcgctc cctttgacgt
    68221 tgagccgcgg aacgttctta accgcctgtg gcagcagcta cgccagcgcg gattgttccc
    68281 ggttgtagcg gtagagctgg agttctattt actggatcgt cagcgcgacg ctgaagggta
    68341 tctgcaaccg ccctgcgcgc ccggcaccga tgaccgcaat acacaaagcc aggtttactc
    68401 cgttgataac ctcaaccact tcgccgacgt gctcaatgat attgatgaac tggcgcagtt
    68461 acagttaatt cccgccgacg gtgcggtcgc cgaagcctcg ccgggtcagt ttgaaatcaa
    68521 cctttaccat accgataacg tgctggaagc ctgcgatgat gcgctggcgc taaaacgcct
    68581 ggtgcgtctg atggcagaaa agcataagat gcacgccact tttatggcga agccgtatga
    68641 agagcacgcg ggcagcggga tgcatatcca tatcagtatg caaaataatc gtggcgagaa
    68701 tgtgctttct gacacagaag gcgaagattc gccgctgctg aaaaagatgc tcgccgggat
    68761 gattgacctg atgccgtcgt cgatggcgtt gctggcacca aacgtgaact cgtatcgccg
    68821 cttccagccg ggaatgtatg tgccgacgca ggcgtcgtgg ggccataaca accgcaccgt
    68881 cgccctgcgt attccgtgcg gcgaccgtca taatcaccgc gtggaatatc gcgtggcggg
    68941 tgccgatgcc aacccatatc tggtgatggc agcgattttt gccggtattt tgcatggcct
    69001 tgataacgag ctgccgttgc aggaagaagt cgaaggcaac gggctggaac aggaaggctt
    69061 acccttcccg attcgccaga gcgatgccct aggtgagttt atcgagaatg atcacctgcg
    69121 ccgctattta ggcgaacggt tttgccatgt gtatcacgcc tgtaaaaatg atgagctgtt
    69181 gcagtttgag cgcctcatca cagaaacaga aattgagtgg atgttgaaaa acgcgtaatt
    69241 ccccatgcgg ggttgtttca tcggcctgag cggagccagg cctgacattt gctggtaatc
    69301 cagacatttc ccggatgtcg cgttatggag cgcaggcggc aacgggcttc cgttaacgat
    69361 taagactgtg acgaggaaat gagatgatgc cgatgattaa atccccgcat ggcgagggag
    69421 gctgcgtatg cgcccctcct gctactgact ggactccgcc ccctttgctt cccttgctaa
    69481 acaggtttga tttcaggtcg acacgaccgc aaaccttatt acgcagggga ggcagcaatt
    69541 atggctatta attcaccact gaatattgct gcgcaacccg gcaaaacccg tctgcgaaaa
    69601 tcactgaaat tgtggcaggt ggtaatgatg ggtctggcct atctcacgcc gatgaccgta
    69661 tttgatactt ttggtattgt ctccggcatt agcgacggtc acgttccggc gtcctatttg
    69721 ctggcgctgg cgggcgtgct gtttaccgct atcagctacg gcaaactggt tcgccagttt
    69781 ccggaggccg gttcggccta tacctacgcg caaaagtcga ttaatccgca cgtcggattt
    69841 atggtcggct ggtcatcact gctggattat ctctttttgc caatgatcaa cgttttgttg
    69901 gcgaaaatct atctctccgc cctcttcccg gaagtgccgc cgtgggtgtg ggtggtaacc
    69961 ttcgtcgcca ttttaaccgc cgcgaatctg aagagcgtca acctggtcgc taacttcaat
    70021 accctgtttg tactggtgca aatctccatc atggtggtgt ttatcttcct ggtggttcag
    70081 ggactgcata aaggagaagg cgttggcacc gtctggtcac ttcagccgtt tatcagcgag
    70141 aacgcgcacc tgatcccgat tattaccggt gcgacgattg tctgtttctc gttcctcggt
    70201 ttcgatgcgg tgaccacgct ttcggaagag acgccggacg ccgcacgcgt gatcccgaaa
    70261 gccatcttcc tgacggcggt atacggcggc gttatcttta tcgcggcgtc gttctttatg
    70321 cagctgttct ttcccgatat cagccgcttt aaagacccgg acgccgcact gcctgaaatt
    70381 gcgctgtacg tcggcggcaa gctctttcag tcgattttcc tctgcaccac gtttgtgaac
    70441 acattagcgt ctggcctggc ttcacatgcc agcgtgtcgc gtctgctgta tgtgatgggg
    70501 cgtgacaatg tgtttccgga gcgcgtgttt ggctatgtgc acccaaaatg gcggactccg
    70561 gcactcaacg tcattatggt cgggattgtc gcgctgtcgg cgctgttctt tgatttagtc
    70621 accgcgacag cactgattaa cttcggtgct ctggtggcgt ttaccttcgt gaatctgtcg
    70681 gtgtttaatc atttctggcg gcgtaaagga atgaataaaa gctggaagga tcacttccac
    70741 tatttgctga tgccgctggt tggcgcgctg acggtgggtg tgctgtgggt taacctagag
    70801 tcaacgtcac tgacactcgg tctggtatgg gcttcgttag gcggcgcata tttgtggtat
    70861 ctgatccgcc gctatcgcaa agtgccgctg tacgaaggtg acagaacgcc ggtgagcgaa
    70921 acgtaatagc cggatgcgcg gcgcattatc ctgcctgagg gtaacgcgcc gcgccattaa
    70981 ctataaaaag atgtatgacc cggatcacga gtgctatcat ccgcccttat gcttagcgca
    71041 ttaaccccag gggcaaataa tgaaccacga tatcccgcta aaatattttg atattgccga
    71101 tgagtacgcg accgaatgcg cagagcctgt cgcagaggct gaacgcacac cgctggccca
    71161 ctacttccag ttactgctca cccgtttgat gaacaatgaa gagatcagcg aagaagccca
    71221 acatgaaatg gctgctgaag cggggattaa tcccgtacgc attgatgaga tcgcagagtt
    71281 tttgaatcaa tggggtaatg agtaattatt taattgcaga cgatcggtca gtatcgttgt
    71341 tcggataaag cgttcacgcc gcatccggct aacaatgaca cgcactgcag cgtgctttaa
    71401 tgggtttctc acgatcgtac cgctctgctc ctcgctaagt tgttctgtga gttatagtta
    71461 tagagaaatc acgggtacga atgttgaaca gatggcgacg ccacctgttc aacgaccaac
    71521 cacacggccc tcattacgac ccctgaacac aaacggtaat ggcaaatgtc attaaatatt
    71581 agtaagatag cctctttaca taaaatccct taatattatg cgccaggtat tatcgtctct
    71641 tttggtgatt gctggacttg tgagtggtca ggcaatcgcc gcgcctgaat cccccccgca
    71701 tgctgatatc cgcgacagcg gttttgtcta ttgcgtcagc gggcaagtca acacctttaa
    71761 cccatccaaa gcgagcagtg ggttaattgt cgataccctt gccgcccagt tttatgatcg
    71821 actgctggat gtcgatccct atacctatcg cctgatgccg gaacttgccg aaagctggga
    71881 agtactcgac aacggcgcga cctatcgctt ccacctgcgt cgcgatgttc cgtttcaaaa
    71941 aaccgactgg tttactccca ctcgtaaaat gaatgccgac gatgtggtgt ttaccttcca
    72001 gcgaattttt gaccgcaaca acccgtggca taacgtcaac ggcagcaact tcccctactt
    72061 cgacagcctg caatttgccg ataacgtgaa aagcgtccgc aaactggata atcataccgt
    72121 tgagttccga ctcgcccagc cggatgcttc ttttttgtgg cacctcgcaa cccattatgc
    72181 ttcggtcatg tcggcagaat atgcccggaa gttagagaaa gaagatcgcc aggagcaact
    72241 cgaccgtcaa ccggtcggca ccggtccgta tcagttgtcg gaataccgcg ccgggcaatt
    72301 tattcgccta caacgtcatg atgacttctg gcgcggtaaa ccgttaatgc cgcaggtagt
    72361 ggtggattta ggctccggcg gcaccggacg tctgtcgaaa ctcctgaccg gggaatgcga
    72421 cgttctggcc tggcctgctg ccagccagct atccattttg cgtgacgacc cgcgcttgcg
    72481 tttaacgctg cgtcctggga tgaacgtcgc ctatctggca tttaacaccg ccaaaccgcc
    72541 gctaaataat cccgctgtcc gccatgcact ggcactggcg attaataacc agcgcctgat
    72601 gcaatccatc tattatggta cggctgaaac ggcggcctct attttaccgc gcgcctcgtg
    72661 ggcctatgac aacgaggcta aaattactga atacaatccg gcgaaatcgc gcgaacagtt
    72721 gaaggcgttg gggctggaaa acttaacgct gaaactgtgg gtgcccacac gttcgcaggc
    72781 gtggaacccc agtccactga aaactgccga actgattcag gcggatatgg cgcaggttgg
    72841 cgtaaaagtg gtgattgtgc cggtagaagg tcgctttcag gaggcgcggt tgatggatat
    72901 gagccatgat ctgacgttat ccggttgggc gacggacagt aacgacccgg acagtttctt
    72961 ccgtccttta ctgagctgcg cggcaattca ttcacagacc aacctcgccc actggtgcga
    73021 tccgaaattc gacagcgtgt tgcgtaaggc gctctcctcg cagcagctgg cggcgcgtat
    73081 tgaagcctat gacgaagcgc agagtattct ggcgcaggaa ttgcccattt tgccgctggc
    73141 gtcgtcattg cgtttgcagg cctatcggta cgatatcaaa ggtctggtac ttagcccgtt
    73201 tggtaacgcc tcctttgctg gggtgtatcg cgagaaacag gatgaggtga aaaaaccatg
    73261 attatcttca ccttacgccg cattttgtta ttgattgtca ccttgttcct gctgaccttc
    73321 gttggcttca gcttgagcta tttcacccct catgcgccgt tacaaggcgc gtcactgtgg
    73381 aatgcctggg tgttctggtt taacggcctg atccactggg attttggtgt ttccagcatt
    73441 aacggtcaac cgattgccga acagttaaaa gaggtcttcc cggcgacgat ggaactgtgc
    73501 atcctcgcct tcggttttgc gctgattgtt ggcatccccg tggggatgat tgccgggatt
    73561 acgcgccata agtggcagga taacttgatc aacgccatcg ccttactggg cttttcaatc
    73621 ccggtgttct ggctggcgct tctgttgacg ctgttttgtt cactcacgct aggttggttg
    73681 cccgtttcag ggcgtttcga tctgctctac gaagtgaaac cgattaccgg ttttgcgttg
    73741 attgatgcct ggctttcgga ctcaccatgg cgggatgaaa tgatcatgag cgcaatccgc
    73801 catatgatat tgcccgtgat caccctgtcg gttgcgccaa caactgaagt gatccgcctg
    73861 atgcgtatca gcactatcga agtgtatgac cagaactatg taaaagcggc ggcgacccgc
    73921 ggtttgtcgc gctttactat tttgcgtcgc cacgttctgc ataacgcgtt accgccggtt
    73981 attcctcgcc tgggcttaca gttttccacc atgctgacgc tggcgatgat caccgaaatg
    74041 gtttttagct ggccaggttt agggcgctgg ttaattaacg ccatccgcca gcaggattac
    74101 gcagccattt ccgccggagt gatggtgtgt ggctcactgg tcattattgt taacgtgatt
    74161 tctgatattt tgggtgccat ggctaaccct ctgaaacata aggaatggta tgccttacga
    74221 tagcgtatac agcgaaaagc gcccgccggg cacgctgcgt accgcctggc gcaaatttta
    74281 tagtgacgcc tctgcgatgg tcggcctgta cggctgcgcg gggctggctg tactgtgtat
    74341 ttttggcggc tggtttgcgc cttacggcat cgaccagcaa tttctcggtt atcaattatt
    74401 gccgccgtca tggtcgcgct atggcgaagt ttctttcttc ctggggactg acgacctcgg
    74461 acgcgatgtt ttaagccgtt tactgagcgg agctgcgcca accgtgggtg gcgcatttgt
    74521 ggtgacgctt gccgcgacga tctgtggcct ggtactgggc accttcgccg gggcgacaca
    74581 cggcctccgc tcagcggtgc ttaaccatat tctggatacc ttactggcga tcccttcgct
    74641 gctgttggcc attatcgttg tagcgtttgc cggaccgagt ttgtcccacg ctatgtttgc
    74701 tgtctggctg gcattgctgc cgcgtatggt acgttcgatt tacagcatgg tgcatgacga
    74761 actggaaaaa gagtacgtta tcgccgcccg tctggatggc gcatcaacgc tgaatattct
    74821 ctggtttgct gtgatgccaa acatcaccgc cgggctggtc accgagatca cccgcgcact
    74881 gtcgatggca attctcgata tcgccgcgct gggctttctc gatctcggcg cacaactccc
    74941 ctcgcctgaa tggggagcga tgctcggtga tgcgctggaa ctgatttatg tcgccccgtg
    75001 gactgtcatg ctgccaggtg cggcaattat gattagcgtg ttgttggtta acctccttgg
    75061 cgatggcgtt cgtcgtgcga ttattgcggg ggtggaataa tgccattact cgatattcgt
    75121 aacctgacca ttgaatttaa aaccggtgat gagtgggtta aagccgtcga ccgggtaagt
    75181 atgaccttaa ccgaaggtga aatccgcggt cttgttggtg aatccggttc cggcaagagt
    75241 ttgattgcga aagcgatttg tggggtgaat aaagataact ggcgtgttac tgctgaccgt
    75301 atgcgttttg atgatatcga tttgctgcgt ctctccgcac gcgaacggcg caaactggtt
    75361 ggccataacg tgtcgatgat tttccaggaa ccgcagtcgt gtcttgaccc ttcagaacgt
    75421 gtgggtcgcc agttgatgca aaacatccca gcctggacct ataaaggccg ttggtggcag
    75481 cgttttggct ggcgcaaacg ccgtgccatt gaactgctgc accgcgtggg gattaaagat
    75541 cacaaagatg cgatgcgcag ttttccctat gagttgaccg aaggtgaatg tcagaaagtg
    75601 atgatagcca ttgcactggc gaatcaaccg cgtctgctga ttgctgacga accgaccaac
    75661 tcaatggagc caacaaccca ggcgcaaatc tttcgcctgc tgacgcgtct caaccaaaac
    75721 agcaatacca ctattttgct tatcagccat gacttacaaa tgcttagcca atgggcggat
    75781 aaaattaacg tgctttactg cggtcaaaca gtggaaaccg cgccgagtaa ggagttggtg
    75841 acgatgccac atcatcctta tacccaggcg ctgatccgcg cgataccaga cttcggcagc
    75901 gcgatgccgc ataaaagtcg cctcaatacg ctgcccggcg ctatcccact gctggaacag
    75961 ttaccgattg gttgtcgtct ggggccacgt tgcccgtatg cacaacgaga atgcattgtg
    76021 acgccacgtt tgacgggggc gaaaaatcat ctctatgcct gtcatttccc gctgaacatg
    76081 gagaaagagt gagatgatcg aaacgctgct tgaagtgcgt aatttaagta aaacgttccg
    76141 ctaccggacc ggctggtttc gtcgtcagac cgtagaagcg gtaaaaccct tgagctttac
    76201 gctacgtgaa ggccagacac tggcgattat tggcgagaat ggttcgggta aatccacgct
    76261 ggcaaaaatg ctggcgggaa tgatagagcc taccagcggc gagttattga ttgacgatca
    76321 tccactgcat tttggcgatt attccttccg cagtcagcgt attcgcatga tttttcagga
    76381 tccttcgacc tcgttgaatc cccgtcaacg tatctcgcaa attctggatt ttccactgcg
    76441 cctgaacacc gacctggaac cggaacagcg tcgcaaacag attattgaaa cgatgcgtat
    76501 ggttgggctg ctaccggatc acgtcagtta ctatccgcat atgttggcac ccggacaaaa
    76561 acagcgtctg ggtctggcgc gcgcgctgat attgcgccca aaagtcatta ttgccgatga
    76621 agccctcgct tcactggata tgtcgatgcg ttcgcagttg attaatctga tgctggaatt
    76681 acaggaaaaa cagggcattt cgtatattta tgttacccag catatcggaa tgatgaagca
    76741 cattagcgac caggtgctgg tgatgcatca gggcgaggtt gtcgagcgag gcagcaccgc
    76801 ggatgtgctg gcatcgccgc tgcatgaact caccaaacgg ctgattgccg ggcactttgg
    76861 cgaagcattg acagcggatg cgtggcgtaa agatcgctaa ttttctgaat cctccttcca
    76921 gattatccac ctcattctga caagagatta aatcttgtca gaatgaggtg atggataaaa
    76981 taaaatcaaa tgcgcgtgat ttaagacgca atctcacttt gcaggaacga aagctctggc
    77041 gatatcttcg cagccgacgt tttggtgatt tcaaatttcg ccgtcaacat ccggtgggga
    77101 gctacattct cgattttgct tgctgctcgg cgcgcgtagt cgttgagctg gatggtgggc
    77161 agcatgattt ggcagttgcc tatgatacca ggcgcactag ctggcttgag tcgcagaact
    77221 ggaccgtgct gcgtttctgg cataacgaga ttgattgtaa tgaggaggcg gtgctggaga
    77281 ttattctgca ggaactgaac cgccggtcac cctcaccctg aaagggcgag ggggccgacc
    77341 gagccgaata gctgttgtgg tgaaaacatg gagacagtgc tggagaatat tcggcaaggt
    77401 ctgaaccatc ccagccatcg ccataaaagg gttaggggct gtatgagcct gtttgttgct
    77461 ggggtaacaa tatttgcaca atatggtccc ctcgcccctc tggggagagg gttagggtaa
    77521 ggggaaaagc gcccaccctg ccgcagcctg ctccggtcgg acctggcaac tatagctact
    77581 cacagccagg ttgattataa taaccgttta tctgttcgta ctgtttacta aaacgacgaa
    77641 tcgcctgatt ttcaggcaca acaagcatca acaataagga ttaaagctat gggttttctt
    77701 tccggtaagc gcattctggt aaccggtgtt gccagcaaac tatccatcgc ctacggtatc
    77761 gctcaggcga tgcaccgcga aggagctgaa ctggcattca cctaccagaa cgacaaactg
    77821 aaaggccgcg tagaagaatt tgccgctcaa ttgggttctg acatcgttct gcagtgcgat
    77881 gttgcagaag atgccagcat cgacaccatg ttcgctgaac tggggaaagt ttggccgaaa
    77941 tttgacggtt tcgtacactc tattggtttt gcacctggcg atcagctgga tggtgactat
    78001 gttaacgccg ttacccgtga aggcttcaaa attgcccacg acatcagctc ctacagcttc
    78061 gttgcaatgg caaaagcttg ccgctccatg ctgaatccgg gttctgccct gctgaccctt
    78121 tcctaccttg gcgctgagcg cgctatcccg aactacaacg ttatgggtct ggcaaaagcg
    78181 tctctggaag cgaacgtgcg ctatatggcg aacgcgatgg gtccggaagg tgtgcgtgtt
    78241 aacgccatct ctgctggtcc gatccgtact ctggcggcct ccggtatcaa agacttccgc
    78301 aaaatgctgg ctcattgcga agccgttacc ccgattcgcc gtaccgttac tattgaagat
    78361 gtgggtaact ccgcggcatt cctgtgctcc gatctctctg ccggtatctc cggtgaagtg
    78421 gtccacgttg acggcggttt cagcatcgct gcaatgaacg aactcgaatt gaaataatca
    78481 ttctgttggt aaatattggg cggcgttctg ccgcccgtta tctctgttat acctttctga
    78541 tatttgttat cgccgatccg tctttctccc cttcccgcct tgcgtcagga taacgatttc
    78601 ctttacgacc aaggagcgcc catggaacaa cgccacatca ccggcaaaag ccactggtat
    78661 catgaaacgc aatccagtac tgcggagtat gacgttctgc ctctggtccc ggaagccgca
    78721 aaggtcagcg atccctttct gctcgacgtg atccttgatg aagaaacgct ggctcccttc
    78781 ctttcatggc tggtccctgc gcgcgttctt gcagtggaat tgttccctga ccagcttacc
    78841 gtgacccgtt cacagacctt caccgcttat gaacgcttgt ctacggccct gacggttgct
    78901 caggtttgcg gcgtccagcg gttatgtaac tactattcgg cgcgacttac gccgctcccc
    78961 gggcctgatt cctccaggga aagcaatcat aggttggcac aaatcacgca atatgcccgc
    79021 caactggcta gctcgccttc tattatcgac aaccgatcgc gccagcatct gaatgacgtc
    79081 ggtcttactg ccggggactg tgtgatcatt aaccaaatca ttggttttat tggctttcag
    79141 gcgcggacca ttgcgacatt tcaggcttat ctcgggcacc cggtacgctg gttacccggt
    79201 ctggaaatac aaaactacgc cgacgcgtca ctgtttgctg atgaatcaat acgctggcga
    79261 agcagctatg aggtggaaaa actacctgaa gagtacacaa aaagttcaac agcagaactt
    79321 tgccaactgg ccgaaacact ctctctccac cctatttcac tttcccttct cgaaaggttg
    79381 ttaaacagta cacgggttaa tacacagccg gataataagc ttgcggcgtt gttatgcgcg
    79441 cggataaatg gcagtcctgc ttgttttgcc gcctgtatgg attcatcaaa tgaatataaa
    79501 aaaatcagcc cccttctgcg caagggcgaa aatgaaatta accaatgggc tgaccgtcat
    79561 tctgttgagc acgctaccgt tcaggcgata caatggctga cccgagcacc cgatcgcttt
    79621 agcgccgccc agttcagccc tttactcgaa cacgaaaaat catcaacgca gattattaat
    79681 ctgctggtat ggagcgggct gtgtggctgg ataaatcgct taaaaatcgc gttgggtgag
    79741 acatattaac cttgccgcgt cagacagatt cgcgtaaaac tgtcagccgc tctaatggcc
    79801 accaaaatag acaattatgt ttcaggacaa cccgctgcta gcgcagctta aacagcaact
    79861 gcattcccag acgccacgcg ctgaaggggt ggtaaaagcc acagaaaaag gctttggctt
    79921 cctggaagtc gacgcgcaaa aaagttattt cattccgccg ccgcagatga aaaaagtcat
    79981 gcatggcgac cgaattatcg cggtgatcca cagtgaaaaa gaacgtgaat ccgcagagcc
    80041 agaagaactg gttgaaccgt tcctgactcg tttcgtgggt aaagttcagg gcaaaaatga
    80101 ccgtctggcc atcgttcctg atcatccact cttaaaagac gccattcctt gccgcgcagc
    80161 ccgtggcctg aaccacgagt ttaaagaagg cgactgggcg gttgccgaaa tgcgccgtca
    80221 tccgctgaaa ggcgatcgtt ctttctatgc tgaactgaca caatacatca cttttggtga
    80281 cgaccacttt gtaccgtggt gggttaccct tgcgcgccat aatctggaaa aagaagcacc
    80341 agacggcgtc gctaccgaaa tgctcgatga aggtctggtt cgtgaagatc tgaccgcgct
    80401 ggattttgtc accatcgaca gtgccagcac agaagatatg gatgacgccc ttttcgctaa
    80461 ggcgttgccg gatgacaaac ttcagctgat tgtggcgatt gccgatccaa ccgcgtggat
    80521 tgctgaaggc agcaagctgg acaaagccgc gaaaattcgc gcattcacca actatctgcc
    80581 tggcttcaac atccctatgc tgcctcgcga gctttctgac gatctctgct cactgcgcgc
    80641 caatgaagtc cgcccggtac tggcatgccg catgacgctc tccgctgatg gcaccattga
    80701 agataatatc gaattctttg ccgccaccat cgaatccaaa gcaaagctgg tgtatgacca
    80761 ggtttctgac tggctggaaa ataccggtga ctggcagcct gaaagtgaag caattgccga
    80821 acaagtccgt ttgctagcgc aaatttgcca acgccgcggc gagtggcgtc ataaccacgc
    80881 actggtgttt aaagatcgcc cggattaccg ctttattctc ggtgaaaaag gtgaagtgct
    80941 ggatatcgtc gccgagcctc gtcgcattgc caaccgtatc gtcgaagaag cgatgattgc
    81001 cgctaacatt tgtgcggccc gcgtactgcg cgataagctc ggttttggca tctataacgt
    81061 gcatatgggc tttgatccgg cgaatgccga cgcgctggca gcgttgctga aaacgcacgg
    81121 tctgcatgtc gatgccgaag aagtgctcac gctggacggt ttctgcaaac tgcgtcgtga
    81181 actggacgcg caaccaactg gtttcctcga cagccgcatt cgtcgcttcc agtcatttgc
    81241 tgaaattagc actgaacccg gtcctcactt tggcctcggt ctggaagcat acgccacctg
    81301 gacttcgccg atccgtaaat atggcgacat gatcaaccac cgtctgctga aagcggttat
    81361 caaaggcgaa actgcgacgc gcccacagga tgaaatcact gtccaaatgg ccgagcgtcg
    81421 ccgtctcaac cggatggcag aacgtgatgt tggtgactgg ttatacgcac gcttcctgaa
    81481 agacaaagcc gggaccgaca cccgtttcgc agcggaaatt gtcgatatca gccgtggcgg
    81541 catgcgtgtt cgtttggttg ataacggcgc tatcgccttt attccggcac ctttcttaca
    81601 cgctgtgcgc gatgaactgg tttgcagcca ggaaaacggc actgtacaaa ttaaaggtga
    81661 aacggtttac aaagtgactg acgttattga cgtcactatt gccgaagtcc gcatggaaac
    81721 ccgcagcatt attgcgcgcc cggtcgcgta atctcctttc acggcccatt cctcatggat
    81781 gggccgttta tttccccgct ctaccttcgt tatatccagg cagatttttt aactgacttt
    81841 cgtttgaaaa ctggcgtttt tccaaaactg gattacaaat aaatatataa aaaaaacaat
    81901 gcgtttagcc gccgttaatt tcatgtaagt catgttgttc cttttattta accgcggact
    81961 ccgcagttaa ccggaggata tgcatcatga aaaccgttag ggagtccaca acgttgtaca
    82021 actttctcgg atcgcacaat ccatactggc ggttgacgga aagcagcgat gttttgcgct
    82081 tttctaccac cgaaaccaca gaacctgatc gtactttgca gttatctgcc gaacaggctg
    82141 ctcgcatcag ggaaatgacg gtcatcacct ccagcctgat gatgagtctg accgtcgatg
    82201 agagcgatct ttctgtgcat ctggtaggac gaaaaatcaa taaacgggaa tgggctggca
    82261 acgcgtctgc atggcatgac acaccggcgg ttgctcgtga tttatcacac gggctttcct
    82321 ttgctgagca ggtagtttct gaagcacatt ccgcaatagt cattctcgac agccggggga
    82381 atattcaacg cttcaatcgg ttatgtgaag attacacagg gttgaaagaa cacgacgtca
    82441 ttgggcaaag cgtgtttaaa ctgtttatga gccgtcgtga agctgcggca tccaggcgca
    82501 ataaccgtgt attttttcga agcggcaatg catatgaagt cgaactgtgg ataccaaaat
    82561 gtaaaggcca gcggctgttt ctgtttcgca ataaatttgt ccacagcggc agtggcaaaa
    82621 acgagatttt tttaatctgt tccggcaccg acattaccga agagcgccgc gctcaggagc
    82681 gactgcgtat tctggcaaat accgacagta tcaccggact gccgaatcgt aacgcaatgc
    82741 aggatttaat cgatcacgct attaatcatg cagataacaa taaagttggg gttgtgtatc
    82801 ttgatttgga taatttcaaa aaggtcaatg acgcctatgg gcatttgttt ggtgaccagt
    82861 tattacgcga cgtgtcattg gctattttaa gctgtctcga acatgaccag gtgttggcgc
    82921 gtccaggtgg ggatgagttt ctggtactgg catccaacac ctcacaaagc gcgctggaag
    82981 caatggcatc acgaattttg acccgcttac ggctcccctt tcgcattggt ttaattgaag
    83041 tttataccag ctgttcagta ggtattgcac tctctcccga acatggttca gacagcacgg
    83101 ctattattcg tcacgccgac acagcaatgt acacagcgaa ggaaggcgga cgaggacaat
    83161 tttgcgtttt tactccagaa atgaatcagc gggtatttga atatctctgg ctggatacca
    83221 acttgcgtaa agcactggaa aacgatcagt tggttattca ctatcaaccg aaaatcacct
    83281 ggcgtggcga agtgcgcagt ctggaagcac tagtacgttg gcagtcacct gaacgtgggt
    83341 tgattccacc gttggacttc atttcctacg ccgaagagtc agggctaatt gtgcctttag
    83401 gccgttgggt gattctcgat gtcgtacgcc aggtggcaaa gtggcgggat aaaggcataa
    83461 acctgcgagt ggcggtaaat atttctgcac gtcagctcgc cgatcaaacc attttcaccg
    83521 ccctgaaaca ggttctccag gaactcaatt ttgaatactg ccctatagat gttgaactga
    83581 cagagagttg tctgattgag aatgatgaac tggcactgtc tgttattcaa caatttagcc
    83641 aactaggtgc gcaagtgcat ctggatgatt ttggtaccgg ctactcttca ctttcgcaac
    83701 tggcgcgctt tccgatcgat gccatcaaac ttgaccaggt ttttgttcga gatattcaca
    83761 aacaacctgt ctcgcagtca ctggtccggg cgatcgtcgc tgtggcccag gcattgaatc
    83821 ttcaggtgat cgccgaaggt gtagagagtg caaaggaaga tgctttttta accaagaacg
    83881 ggatcaatga gcggcaagga tttttgtttg ccaaaccgat gcccgccgtc gccttcgaac
    83941 gctggtataa acgctatctg aagcgcgcat aagtagatga atatatatac ttagcgctat
    84001 atcccgtcat tatatatcgt attcctggat gataattagc cgttgctgtt aaacacttct
    84061 cttttagcgg caatttttgc attattcatt ttccactttt gctataagga tgtccttgat
    84121 gtctgaattt gatgcccagc gcgttgccga acgtattgat attgtgttag atatccttgt
    84181 ggcaggcgat taccactctg cgatccataa tctcgagata cttaaagcag aactcttgcg
    84241 ccaggttgct gaatctacgc cagacatccc gaaggcaccg tgggagattt aacaatcgtg
    84301 ccttcaggtt ttcctatttg aggatgcccg gcgcgtcagt atttttttat ttagtattat
    84361 aacgttataa gaattacagc gatgaattcc cgacaacaaa ctattctaca gatggtcatt
    84421 gaccagggtc aggttagcgt aaccgatctg gcaaaagcca ctggagtttc tgaagttacc
    84481 attcgccagg atctcaacac cctcgaaaaa ctgagttacc tccgccgtgc acatggcttt
    84541 gcagtttcgc ttgatagtga tgacgtcgaa acccgtatga tgagcaacta tacgctgaag
    84601 cgtgaactcg ccgagtttgc cgcgtcactg gttcaaccgg gcgaaaccat ctttatcgaa
    84661 aatggtagca gcaatgccct gctcgcccgg actctgggcg aacagaagaa aaatgtcact
    84721 atcatcacag tcagcagcta cattgcgcat ttgctgaaag acgcgccttg tgaagtcatt
    84781 ttgctcggtg gcgtgtacca gaaaaaaagc gaaagtatgg ttggcccttt gacacgccag
    84841 tgcatccagc aggtacattt cagcaaagca tttattggta ttgatggctg gcaacctgaa
    84901 actggattca ccggtcgcga tatgatgcgt accgatgtgg tcaatgccgt gctggaaaaa
    84961 gagtgcgaag cgatagtcct gactgacagc tcgaaatttg gtgctgtaca ttcatactcc
    85021 atcggtcccg ttgagcgatt caatcgcgtg attaccgatt cgaaaatacg cgccagcgat
    85081 ctgatgcatc ttgagcacag taaactcacc gttcacgtcg ttgacattta accatttccc
    85141 ttctctacgg atgatttgca gtttggcaaa tcatccgctc taagatgatt cctggttgat
    85201 aattaagact atttacctgt tattaacact ctcaagatat aaaattatta tcagcgatat
    85261 aacaggaagt cattatcacc tgcgtgatat aaccctgcgc gcgagcagat ttcacggaat
    85321 aatttcacca ggcttattct tagctattat agttatagag agcttacttc cgtgaatcat
    85381 aaattcagga gagagtatta tgtttgtaac gagcaaaaaa atgaccgcgg ctgttctggc
    85441 aattactttg gcaatgtctc tgagtgcctg ttctaactgg tctaaacggg accgcaacac
    85501 cgcaatcggc gcgggtgcag gggcattagg cggtgcagta ctgaccgatg gcagtacgtt
    85561 gggtacatta ggtggtgcag ctgtcggtgg tgttattggt caccaggtcg gtaaataatc
    85621 gtaaataaat gtcgattatc gactcgcaat tataatacgc ttgattctgt tcagtacgaa
    85681 ataactgaat aatacgcaca gtaaaatatt cgaaagccac ggatatatcc gtggcttttt
    85741 atgttaaccg cctgcgagtt ttaccttcat ccctttcgct tcaagtagtg attttaataa
    85801 atcacgctta tcgccctgga tttcaataac tccatcttta actgctccgc cgcagccgca
    85861 ttttttcttc agttccgctg caagttttgt cagttcggca tcatcgagat cgacaccggt
    85921 aatcaggcaa acgcccttac ctttacgtcc actggtctga cgctgaatac gcaccacacc
    85981 gtcgccttta gggcgtacag gggccgcttt gggctcatca atacgtccgg tttccgttga
    86041 gtagaccaga cggctgttgg aatcactcat catgcactcc gctgtaaaga ggcgttgatc
    86101 gctttcagcg tctgcgctgg atctaccgat tgcgttaccg ggcgaccaat caccatataa
    86161 tcaacaccag ccgacaacgc ctgttctggc gtcataatgc ggcgctggtc accagcttca
    86221 ctcccctgcg gacgaatgcc cggcgtaacc agtttgaact cctgaccgaa tacctgttta
    86281 aagcgcacag cttcctgagc agaacacacc acaccatcaa ggctacattt ttgcgtcagt
    86341 gccgccagac gttctgcata atctgcaggt gacagtgtca tgccaagatc gaccaggtcg
    86401 ctggcttcca tgctggtcaa cactgtcaca gcaatcaaaa gcggtgcatc tttgccaaac
    86461 ggaaccagtg cctcacgcgc tgcggtcatc atacgcgccc caccagaggc atgaacattc
    86521 accatccaca cgcctaagtc agctgcagca gcgacagcgt gcgctgcagt gttaggaata
    86581 tcgtggaatt tcaggtcaag aaagatatca aaaccacgct gttgaagttc gcgcacaaac
    86641 tgtggcccaa acaatgtaaa catctctttg ccgaccttca gacgacaatc gcgtgggtcg
    86701 atcttgtcga caaaggacag cgcgtcatca cgattatgat aatcaagggc aacaaccaca
    86761 ggagaattcg taacagcgcg ggaagaagat gaagcagtta acgtcatgac cagaccttct
    86821 tgatgatggg caccggaagt ggcgcgaaac aggtaaacgg cgagcattct acccgtggaa
    86881 ataaaaaatt aacagttgcg atttttcccc tggcaggctt tttctgctcc gtcgttgccg
    86941 gagcacaatg gaacatcaat aactagtatg ttgtaactaa agtcggattt ttttaaaaat
    87001 tacaggccat caagaccgcg aatcggttta atggttgacc aggcccgaca agacggacaa
    87061 tgccagtaga gggtgtatgc ggtaaaacca catttctggc agcgataacg aggcttacta
    87121 cgtacctttt cgccaaccat gtcacgcagc accatcaggc tctctttggc acgcccttct
    87181 tccgcttcat ttaagtggta atccattaac ttatggaaca cacgcatggt cggatgacgc
    87241 tgaagctggc gcgtaatata gatctgtgca gcctcactac cgtcgcgcgc ttcgatgata
    87301 tccgcaagca tcaattcagc atcggcaccg gtgttctctt ccaccgcgcg ttgcaggaat
    87361 tctgcccatt cggcagtttt acccaactgc tgatagcagg tttgcaacat ttccagcgtt
    87421 tcgctgacca gttctctgtc ctgggatatc acgcgttgca aactttcgac ggctttggcg
    87481 tattctcctt tcgccataaa cacgcgtccc atcatgatgg atacgcgggc gctgttttta
    87541 tctgccgccg cccctttttt tagcaaggtc atggcacgat cgagatcgtc gctggccata
    87601 tgctgcaggg ctaactcaca gtagaaatgg gcaatttcga cgcgctgttt atctttaccc
    87661 agcttcacca ggcgttcggc aacatcaatt gctttctgcc actcactggt agcctggtag
    87721 atttgtagca actgttgcag agcgccaatg cggaagtcag tttcatcggt cagctgattg
    87781 aacatgtctt ccgcgcggtc gtataacccg gcggccatgt aatcacgccc tagttgttga
    87841 atcgccaaca gacgctgttc ataggtcagc gaggcgcttt ccattagggt ctgatggatg
    87901 cgaatagcgc gatcaacttc gccacgcgaa cggaacaggt ttccgagcgt aaggtgggct
    87961 tcaacggtgc ctgtatcctc tttaagcata tcgagaaaca ggtctaccgc tttatcctgt
    88021 tgattactaa gcaggaagtt aacccccgct acgtaatcac gcgacaagcg gttggcttca
    88081 tcttgcttat tttgttgcgc acttctgcgg cccatatacc agccataggc agcggctaca
    88141 ggcaaaagca gaaacaacaa ctccagcata gaaagttatt ccttcgccgc tgacgagtgc
    88201 ggcactacag ccacgtcagt cgcgggtgaa agctggtttt ccagtcgctt tattttacgt
    88261 tcagcgcgcg ccagggaaac acgaactcgc agccagaaca ggccacaaat caaccaaccg
    88321 atagcaaacc ccgcagcaaa caataccgcc agcaatgtgg aaatacggta ctccccttgc
    88381 gctaacagat aattaaacgt cacctgttga tcgttctgcg cacccaacgt gaccgaaatc
    88441 acgaagatcg ctaacaccag taagaaaatg agtaaatatt tcacattact tcccgttatg
    88501 tggttagagc gaataaatta tggtcaactt accgcaatag ccctttaaag taccattttc
    88561 gcgccgtctg cgaaatggca tccacgcgca ttgttgatga tttaagggct aaattcggaa
    88621 aatcaaccag cgttaacttt cttgttctcg ttgcgctatt tcgcgatttt cttccgcagg
    88681 tggtgttaat ggcccacaaa ttcgttgcgc aagccacgtt gccaccgcca ccagcgccca
    88741 cgaaatcaac gtagctacta ccagatcgcg tggccaatgc atcccgagca gcaggcggct
    88801 tcccatgact cccgttgccc agaccagcaa gatagcaatg gttaacgttc gccgacgcgg
    88861 ccacagcaaa ccaacggcca gcagtgccca actggcagca aacatcgtgt gaccggaagg
    88921 aaaggcaaac cccgtctctt tctgccagtg tgaacgcaaa tattgtggga tatttttctc
    88981 ttcagccaac tgttctttca ctaaatttcc gcgttctgct cgctttaaag tgtagaactc
    89041 atcaaccgga atatgatgtg ttttttccag ccagataaca aaaggtcgtg gttcctggac
    89101 tttgtctttg atccaggatt taacgccttg tcccacaagg attgcggccg ccagaatggc
    89161 aaataataca aaggcagcct taatgcgaaa acgcagacac cagagaaacc agccgaataa
    89221 aatcaaatgt gtaatgacgc cccagggctg ggtgacagtt tcagtaaccc aaaaagccgc
    89281 ttttagtagc caactttgtt ctccaggttg ccaacgccag ccagaaatcc atacggctac
    89341 tggcatgaca agcaatagtg cagctcccac tgcggtacgt ctggcaatcg aacgcatggc
    89401 ctctcctttt tgataagtcc cacaatcata actgaaaacg ccagttccag gaaaaattga
    89461 cagatttgtg ccattccgtg aacgatcgac gcgtcgtgat taggtgaacc ccttctcgtt
    89521 atggcaaaat aagccaatac agaaccagca ttatctggag aatttcatgc agcttaaacg
    89581 tgtggcagaa gccaaactgc caaccccatg gggcgatttc ctgatggtgg gatttgaaga
    89641 actggcaacc ggacacgatc atgtcgcgct agtctatggc gatatttccg ggcatacccc
    89701 ggtacttgcg cgcgtccatt ccgaatgtct gaccggtgac gccctgttca gcttgcgctg
    89761 cgattgtggc ttccagctcg aagcggcatt gacgcaaatt gccgaggaag gccgtggtat
    89821 tttgctgtat caccgtcagg aaggtcgtaa cattggtctg ctgaataaaa tccgcgctta
    89881 cgcactgcag gatcaaggtt acgataccgt agaggctaac caccagttag gcttcgccgc
    89941 tgatgagcgc gacttcactc tttgcgctga tatgttcaaa ctccttggcg tcaatgaagt
    90001 ccgcttgtta accaataacc cgaaaaaagt cgaaattctg accgaagcag ggattaatat
    90061 tgttgaacgc gtaccattga ttgtaggtcg taaccccaat aacgaacatt atctcgatac
    90121 taaagccgag aaaatgggcc atttgctgaa caaataaccc tcttgcattg tgtaattagt
    90181 ttgcttgccg gaagcaaaat aaccggcaag caaatacttg ttacttcaac atattacgaa
    90241 tgacataatg caaaatgccg tcgttctggt agtaggtcaa ctccgtcgcg gtgtcgatac
    90301 gacaacggca gggtacgacc tcctggctac catccgcgcg cgtaagcgtc accggaaccg
    90361 tcgcaccggg ttgtagattt tgcagatcgc caatatcaat cttctcttcc ccggttagtc
    90421 ctaacgtttt acgcgttacg ccttgcggaa attccagcgg caggatgccc atgccaatta
    90481 aattcgaacg gtgaattcgt tcaaacgatt cggcaatcac cacacgaatt ccaagcagac
    90541 gaggaccttt tgccgcccag tcacggcttg agcctgatcc atactctttc ccggcaatca
    90601 ccgccagcgg cgtttgttcc tgcttatagc gcatcgcagc atcataaata gagactacgt
    90661 cgctgtcagg taaatgccgc gtcatccccc cttcaacgcc aggcaccatt tcattacgga
    90721 tgcgaatatt ggcgaaggtg ccgcgcatca tcacttcatg gttaccacgc cgcgaaccgt
    90781 aggagttaaa gtcttttcgc tcaacacccc gaccttgtag atatcgaccc gctgggctgt
    90841 cgggcttaat actgcccgcc ggagagatat ggtcagtggt gactgaatcc cccagcattg
    90901 cgaggatccg cgcaccgtga atatcttcca ctggtgctgg tgttgcctgc atttcatcaa
    90961 agaaaggcga taagcgaata taggttgagt cctcctgcca accgtaggta tcggatcgtg
    91021 tgacgttaat ttccttccac tctgctgtgc cttcaaaaac ttctgcgtac tctttgcgga
    91081 acatttctgt ggagacttgt tctaccgcac gggcaatttc ttgtgccgat ggccagatat
    91141 ctttcagata aaccgggtcg cctttacgat catgaccaat aggctcagca gccaggttga
    91201 tattcatatt tcccgccagc gcataggcaa ccaccagcgg cggcgaggcc agccagttag
    91261 ttttaaccag cggatggata cggccttcaa agttacggtt gccggacagc accgcaccga
    91321 cggttaaatc gccttttttg attgccgttt cgataggatc gggcagcggc ccagagttac
    91381 caatacaggt ggtacaaccg tatcccacaa ggttaaaccc cagttcgtcg agatacggtg
    91441 tcagtttcgc ttttgccaga taatcagaaa cgactttcga acccggtgcc agcgacgctt
    91501 tgacccacgg ttgccgcttg aggcccagag ttacggcttt tttcgccagc aagcctgcgg
    91561 ccatcagcac acttgggtta gaggtgttgg tgcacgaggt tatcgcagca atgaccacag
    91621 cgccatcagg taactgatac tgatgtccgt tcataacata atcgaccggc tggcgatttt
    91681 tatgcgtggc attcacttcc agttcgttac tggcggcaaa tgcttttggt acatcgggca
    91741 gtgcaacgcg atcctgtggg cgttttggcc ctgccaggct cgcttcaacg tcattcatat
    91801 ccagttctaa cgtactggta aaaatcggtt catcgcccgg gttacgccac atgccctgcg
    91861 ctttggcata tttttcgacc aactcaacct gatcttcgct gcgcccgctt aaacgcatgt
    91921 aatcgagggt tacagcatcg attgggaaga agccacaggt ggcaccatat tctggcgaca
    91981 tattggcaat ggtggcgcga tccgccagcg gtagtgaatc cagaccatca ccataaaatt
    92041 cgacgaattt ccccaccacg ccatgtttgc gcagcatttg ggtaacagtg agaaccaggt
    92101 ctgtggcggt aataccttca cgtaatttac cggtaagttt aaagcccact acgtccggga
    92161 taagcatgga aaccggctgg cctaacattg cg
//
LOCUS       DAZUDJ010000010        91061 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.010, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000010 DAZUDJ010000000
VERSION     DAZUDJ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 91061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91061
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.010"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..779)
                     /locus_tag="ACHY1N_001038"
     CDS             complement(<1..779)
                     /locus_tag="ACHY1N_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFS4043380.1"
                     /translation="MSKISGWNFSQNITSADNCKQKNEDLDTWYVGMNDFARIAGGQN
                     SRSNILSPRAFLEFLAKIFTLGYVDFSKRSNEAGRNMMAHIKSSSYIKNNDGSEIMKF
                     VMNNPEGERADLSKVEIEITLASAFNNGIREGHTVIIFTQPDGSTNRYEGKSFERKDE
                     SSLHLITNKILACYQREANKEIARLLNIPQELNNSQDLNNSQVSCKDSVDSTITDLLE
                     KPLNNALLAIRKEHLLLMPYVCNESISYLLGEKGILKEIDDL"
     gene            complement(902..1354)
                     /gene="tabA"
                     /locus_tag="ACHY1N_001039"
     CDS             complement(902..1354)
                     /gene="tabA"
                     /locus_tag="ACHY1N_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin biofilm protein TabA"
                     /protein_id="HFS4043381.1"
                     /translation="MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRL
                     FYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAF
                     LPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA"
     gene            complement(1499..2092)
                     /gene="bdcR"
                     /locus_tag="ACHY1N_001040"
     CDS             complement(1499..2092)
                     /gene="bdcR"
                     /locus_tag="ACHY1N_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709951.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4043382.1"
                     /translation="MVTKKQSRVPGRPRRFAPEQAISAAKVLFHQKGFDAVSVAEVTD
                     YLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLVEVLKEAAR
                     RYSQNGGCAGCMVLEGIHSHDPLARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFM
                     STVMSGLSAKAREGHSIEQLCATAALAGEAIKTLLKE"
     gene            2163..2876
                     /gene="bdcA"
                     /locus_tag="ACHY1N_001041"
     CDS             2163..2876
                     /gene="bdcA"
                     /locus_tag="ACHY1N_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4043383.1"
                     /translation="MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAA
                     KRLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGEALELNADDIDRL
                     FKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
                     ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            3007..3402
                     /gene="yjgH"
                     /locus_tag="ACHY1N_001042"
     CDS             3007..3402
                     /gene="yjgH"
                     /locus_tag="ACHY1N_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFS4043384.1"
                     /translation="MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGT
                     PEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSFHTDPENQFEDIMTVKNEIFSAP
                     PYPNWTAVGVTWLAGFDFEIKVIARIPEQ"
     gene            3683..3817
                     /gene="pyrL"
                     /locus_tag="ACHY1N_001043"
     CDS             3683..3817
                     /gene="pyrL"
                     /locus_tag="ACHY1N_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HFS4043385.1"
                     /translation="MVQCVRHFVLPRLKKDAGLPFFFPLITHSQPLNRGAFFCPGVRR
                     "
     gene            3821..4756
                     /gene="pyrB"
                     /locus_tag="ACHY1N_001044"
     CDS             3821..4756
                     /gene="pyrB"
                     /locus_tag="ACHY1N_001044"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HFS4043386.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAM
                     VGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEE
                     VMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIAT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL"
     gene            4769..5230
                     /gene="pyrI"
                     /locus_tag="ACHY1N_001045"
     CDS             4769..5230
                     /gene="pyrI"
                     /locus_tag="ACHY1N_001045"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009347 - aspartate carbamoyltransferase
                     complex [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HFS4043387.1"
                     /translation="MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPER
                     IDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN"
     gene            5303..5689
                     /gene="ridA"
                     /locus_tag="ACHY1N_001046"
     CDS             5303..5689
                     /gene="ridA"
                     /locus_tag="ACHY1N_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HFS4043388.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPA
                     DVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATF
                     PARSCVEVARLPKDVKIEIEAIAVRR"
     gene            5755..6210
                     /locus_tag="ACHY1N_001047"
     CDS             5755..6210
                     /locus_tag="ACHY1N_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4043389.1"
                     /translation="MAKPRFTNEQIAEILQQSKEGASNKELCEHYQFSVSTLRRWQEQ
                     HADGIRSELKKTESKAQIVFLVFFAIAILLTLIFDKPTGGWVIPPLLIYCVYYIRQYR
                     NISGRHIKKEDIYLSRSVNNSYSALYNLSWTFICFFIFAVIYFFIQVFS"
     gene            complement(6255..8951)
                     /gene="mgtA"
                     /locus_tag="ACHY1N_001048"
     CDS             complement(6255..8951)
                     /gene="mgtA"
                     /locus_tag="ACHY1N_001048"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFS4043390.1"
                     /translation="MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTAVPPSLSAHCLK
                     MAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFN
                     ILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
                     RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLP
                     VEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQES
                     EPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALFALSVAVGLTPEMLP
                     MIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDIS
                     GKTSERVLHSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERR
                     RMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQ
                     GLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVK
                     ILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER
                     IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLE
                     EGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVS
                     QVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPET
                     QTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPL
                     ASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(9092..9145)
                     /gene="mgtL"
                     /locus_tag="ACHY1N_001049"
     CDS             complement(9092..9145)
                     /gene="mgtL"
                     /locus_tag="ACHY1N_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003933616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HFS4043391.1"
                     /translation="MEPDPTPLPRRRLKLFR"
     gene            9330..10277
                     /gene="treR"
                     /locus_tag="ACHY1N_001050"
     CDS             9330..10277
                     /gene="treR"
                     /locus_tag="ACHY1N_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor TreR"
                     /protein_id="HFS4043392.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQRTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPQLVAEHLGVLKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDE
                     GAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLNPVAALPGLAM
                     KQGYENVAKVITPETTALLCATDTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPE
                     IVTVDPGYAEAGRQAACQLIAQVTGRSEPQQIIIPATLS"
     gene            10396..11817
                     /gene="treB"
                     /locus_tag="ACHY1N_001051"
     CDS             10396..11817
                     /gene="treB"
                     /locus_tag="ACHY1N_001051"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HFS4043393.1"
                     /translation="MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANAR
                     PKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARQNMK
                     WHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFL
                     WLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDF
                     GMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHA
                     LIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQ
                     SMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGIN
                     LKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMVIAI
                     IIPIVLTSFIYQRKYRLGTLDIV"
     gene            11867..13522
                     /gene="treC"
                     /locus_tag="ACHY1N_001052"
     CDS             11867..13522
                     /gene="treC"
                     /locus_tag="ACHY1N_001052"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFS4043394.1"
                     /translation="MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHK
                     LGVDAIWLTPFYISPQVDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMV
                     FNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
                     LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPEDLDGD
                     GRRFYTDGPRAHEFLHEMNRDVFTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFN
                     FHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFWCNHDQPRIISRFG
                     DEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELR
                     NDGRDADELLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALA
                     DDSSVFYTYQKLIALRKLEAILTWGNYQDLLPNSPVLWCYRREWKGQTLLVIANLSRE
                     IQPWQPGQMRGNWQLVMHNYEEASPQPCAMTLRPFEAVWWLQK"
     gene            13916..16054
                     /gene="nrdD"
                     /locus_tag="ACHY1N_001053"
     CDS             13916..16054
                     /gene="nrdD"
                     /locus_tag="ACHY1N_001053"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFS4043395.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAA
                     VVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIEREKRGRLNQEI
                     RGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTASYNKHRKTAEEWNIPDAEGYANSRTIKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDEATFWKLLDERLVLARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLNADDDVSEIFKNGRASISLGYIGIHETINALFGGEHVY
                     DNEQLRAKGIAIVERLRQAVDQWKEETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDASRVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            16212..16676
                     /gene="nrdG"
                     /locus_tag="ACHY1N_001054"
     CDS             16212..16676
                     /gene="nrdG"
                     /locus_tag="ACHY1N_001054"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HFS4043396.1"
                     /translation="MNYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRVNSG
                     QLFTKAMEDQIINDLNDTRIKRQGISLSGGDPLHPQNVPDILKLVQRIRAECPGKDIW
                     VWTGYKLDELNATQMQVVDLINVLVDGKFVQDLKDPSLIWRGSSNQVVHHLR"
     gene            complement(16721..17107)
                     /gene="cybC"
                     /locus_tag="ACHY1N_001055"
     CDS             complement(16721..17107)
                     /gene="cybC"
                     /locus_tag="ACHY1N_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313240.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HFS4043397.1"
                     /translation="MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVIEKADN
                     AAQVKDALTMMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
                     EGKVKEAQAAAEQLKTTRNAYHQKYR"
     gene            complement(17290..18642)
                     /gene="pmbA"
                     /locus_tag="ACHY1N_001056"
     CDS             complement(17290..18642)
                     /gene="pmbA"
                     /locus_tag="ACHY1N_001056"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HFS4043398.1"
                     /translation="MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGLADKELLAFDAPDLDLFHPAEVSPDDAIELAARAEQAALQADKRITNTEG
                     GSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQT
                     PEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGSVYRKSTFL
                     LDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIKDGILTQWLLTSYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLPEMKIAGQ
                     "
     gene            18736..19287
                     /gene="yjgA"
                     /locus_tag="ACHY1N_001057"
     CDS             18736..19287
                     /gene="yjgA"
                     /locus_tag="ACHY1N_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="HFS4043399.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     EIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            complement(19443..20816)
                     /gene="mpl"
                     /locus_tag="ACHY1N_001058"
     CDS             complement(19443..20816)
                     /gene="mpl"
                     /locus_tag="ACHY1N_001058"
                     /EC_number="6.3.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HFS4043400.1"
                     /translation="MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEK
                     QGIELIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSARLGESDFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLV
                     GEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHI
                     PWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKAEAAQ"
     gene            20992..21990
                     /gene="fbp"
                     /locus_tag="ACHY1N_001059"
     CDS             20992..21990
                     /gene="fbp"
                     /locus_tag="ACHY1N_001059"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HFS4043401.1"
                     /translation="MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA"
     gene            complement(22023..23018)
                     /gene="yjfF"
                     /locus_tag="ACHY1N_001060"
     CDS             complement(22023..23018)
                     /gene="yjfF"
                     /locus_tag="ACHY1N_001060"
                     /EC_number="7.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0103116 - ABC-type D-galactofuranose
                     transporter [Evidence IEA];
                     GO_process: GO:0042875 - D-galactonate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter, permease
                     protein YjfF"
                     /protein_id="HFS4043402.1"
                     /translation="MIKRNLPLMITIGVFVLGYLYCLTQFPGFASTRVICNILTDNAF
                     LGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVIGDFGLSPLLAFPLVLVMGCAFG
                     AFMGLLIDALKIPAFIITLAGMFFLRGVSYLVSEESIPINHPIYDTLSSLAWKIPGGG
                     RLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLST
                     GLATLAGIVFSIYTQAGYALAGVGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQG
                     LIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQSSPVTRVNIAQR"
     gene            complement(23005..24027)
                     /gene="ytfT"
                     /locus_tag="ACHY1N_001061"
     CDS             complement(23005..24027)
                     /gene="ytfT"
                     /locus_tag="ACHY1N_001061"
                     /EC_number="7.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0103116 - ABC-type D-galactofuranose
                     transporter [Evidence IEA];
                     GO_process: GO:0042875 - D-galactonate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter, ATP-binding
                     protein YtfT"
                     /protein_id="HFS4043403.1"
                     /translation="MPQSLPDTTPPKRRFRWPTGMSQLAALLLVLLVDSLVAPHFWQV
                     VLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGGIDLSVGAVMAIAGATTAAMTVA
                     GFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITSGQIVT
                     FNSPDLSWFGSGSLLFLPTPVIIAVLTLLLFWLLTRKTALGMFIEAVGINIRAAKNAG
                     VNTRIIVMLTYVLSGLCAAIAGIIVAADIRGADANNAGLWLELDAILAVVIGGGSLMG
                     GRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVLIVQSQRFISLIKGV
                     RSRDKT"
     gene            complement(24041..25543)
                     /gene="ytfR"
                     /locus_tag="ACHY1N_001062"
     CDS             complement(24041..25543)
                     /gene="ytfR"
                     /locus_tag="ACHY1N_001062"
                     /EC_number="7.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0103116 - ABC-type D-galactofuranose
                     transporter [Evidence IEA];
                     GO_process: GO:0042875 - D-galactonate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter, ATP-binding
                     protein YtfR"
                     /protein_id="HFS4043404.1"
                     /translation="MTTDQHQEILRTEGLSKFFPGVKALDNVDFSLRRGEIMALLGEN
                     GAGKSTLIKALTGVYHADRGTIWLEGQAISPKNTAHAQQLGIGTVYQEVNLLPNMSVA
                     DNLFIGREPKRFGLLRRKEMEKRATELMASYGFFLDVREPLNRFSVAMQQIVAICRAI
                     DLSAKVLILDEPTASLDTQEVELLFGLMRQLRDRGVSLIFVTHFLDQVYQVSDRITVL
                     RNGSFVGCRETRELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTI
                     APFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTALIKGKPQTLRSPHQASV
                     LGIGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAERFIRQLGIR
                     TPSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCA
                     DGLALLVISSELEELVGYADRVIIMRDRKQVAEIPLAELSVPAIMNAIAA"
     gene            complement(25683..26639)
                     /gene="ytfQ"
                     /locus_tag="ACHY1N_001063"
     CDS             complement(25683..26639)
                     /gene="ytfQ"
                     /locus_tag="ACHY1N_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter
                     substrate-binding protein YtfQ"
                     /protein_id="HFS4043405.1"
                     /translation="MWKRLLVVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNV
                     AKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKD
                     AEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG
                     ASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYA
                     HNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMIDGEANASVELTPNMAGPA
                     FDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY"
     gene            26949..27479
                     /gene="ppa"
                     /locus_tag="ACHY1N_001064"
     CDS             26949..27479
                     /gene="ppa"
                     /locus_tag="ACHY1N_001064"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006796 - phosphate-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HFS4043406.1"
                     /translation="MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGE
                     DAKLIAVPHTKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAE
                     AAKAEIVASFERAKNK"
     gene            complement(27559..27909)
                     /gene="chpB"
                     /locus_tag="ACHY1N_001065"
     CDS             complement(27559..27909)
                     /gene="chpB"
                     /locus_tag="ACHY1N_001065"
                     /EC_number="4.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease toxin ChpB"
                     /protein_id="HFS4043407.1"
                     /translation="MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLG
                     MTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLVNQVRMMDLRARLAKRIGLAADE
                     VVEEALLRLQAVVE"
     gene            complement(27903..28154)
                     /gene="chpS"
                     /locus_tag="ACHY1N_001066"
     CDS             complement(27903..28154)
                     /gene="chpS"
                     /locus_tag="ACHY1N_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin ChpS"
                     /protein_id="HFS4043408.1"
                     /translation="MRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEAQVSNNQLILT
                     PISRRYSLDELLAQCDMNAAELSEQDVWGKSTPAGDEIW"
     gene            complement(28367..28708)
                     /gene="ytfP"
                     /locus_tag="ACHY1N_001067"
     CDS             complement(28367..28708)
                     /gene="ytfP"
                     /locus_tag="ACHY1N_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HFS4043409.1"
                     /translation="MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGA
                     VPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKL
                     IESGDWLDRDK"
     gene            complement(28711..32490)
                     /gene="tamB"
                     /locus_tag="ACHY1N_001068"
     CDS             complement(28711..32490)
                     /gene="tamB"
                     /locus_tag="ACHY1N_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HFS4043410.1"
                     /translation="MSLWKKISLGVVIVILLLLGSVAFLVGTTSGLHLVFKAAERWVP
                     GLDIGKVTGGWRDLTLSDVRYEQPGVAVKAGNLHLAVGLECLWNSSVCINDLALKDIQ
                     VNIDSKKMPPSEQVEEEEDSGPLDLSTPYPITLTRVALDNVNIKIDDTTVSVMDFTSG
                     LNWQEKTLTLKPTSLKGLLIALPKVAEVAQEEVVEPKIENPQPEEKPLGETLKDLFSR
                     PVLPEMTDVHLPLNLNIEEFKGEQLRVTGDTDITVRTMLLKVSSIDGNTKLDALDIDS
                     SQGIVNASGTAQLSDNWPVDITLNCTLNVEPLKGEKLKLKVGGALREQLEIGVNLSGP
                     VDMDLRAQTRLAEAGLPLNVEVNSKQLYWPFTGEKQYQADDLKLKLTGKMTDYTLSMR
                     TAVKGLEIPPATITLDAKGNEQQVNLDKLTVAALEGKTELKALLDWQQAISWRGELTL
                     NGINTAKEIPEWPSKLNGLIKTRGSLYGGTWQMEVPELKLTGNVKQNKVNVDGTLKGN
                     SYMQWMIPGLHLELGPNSAEVKGELGVKDLNLDATINAPGLDNALPGLGGTAKGLVKV
                     RGTVEAPQLLADITARGLRWQELSVTQVRVEGDIKSTDQIAGKLDVRVEQISQPDVNI
                     NLVTLNAKGSEKQHELQLRIQGEPVSGQLNLAGSFDRKEERWKGTLSNTRFQTPVGPW
                     SLTRDIALDYRNKEQKISIGPHCWLNPNAELCVPQTIDAGAEGRAVVNLNRFDLAMLK
                     PFMPETTQASGIFTGKADVAWDTTKEGLPQGSITLSGRNVQVTQTVNDAALPVAFQTL
                     NLTAELRNNRAELGWTIRLTNNGQFDGQVQVTDPQGRRNLGGNVNIRNFNLAMINPIF
                     TRGEKAAGMVSANLRLGGDVQSPQLFGQLQVTGVDIDGNFMPFDMQPSQLAVNFNGMR
                     STLAGTVRTQQGEIYLNGDADWSQIENWRARVTAKGSKVRITVPPMVRMDVSPDVVFE
                     ATPNLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNDNLQPEEPKTASIPINSNL
                     IVHVGNNVRIDAFGLKARLTGDLNVVQDKQGLGLNGQINIPEGRFHAYGQDLIVRKGE
                     LLFSGPPDQPYLNIEAIRNPDATEDDVIAGVRVTGLADEPKAEIFSDPAMSQQAALSY
                     LLRGQGLESDQSDSAAMTSMLIGLGVAQSGQIVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSIATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            complement(32487..34220)
                     /gene="tamA"
                     /locus_tag="ACHY1N_001069"
     CDS             complement(32487..34220)
                     /gene="tamA"
                     /locus_tag="ACHY1N_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HFS4043411.1"
                     /translation="MRYIRQLCCVSLLCLSGSAVAANVRLQVEGLSGQLEKNVRAQLS
                     TIESDEVTPDRRFRARVDDAIREGLKALGYYQPTIEFDLRPPPKKGRQVLIAKVTPGV
                     PVLIGGTDVVLRGGARTDKDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFD
                     SEFTKAQLGIALGLHKAFWDIDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPQFDKARETKVLPLTGVVSPRTENTIETGVGYST
                     DVGPRVKATWKKPWMNSYGHSLTTSTSISAPEQTLDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTESDSTTLVASRYWDLSSGWQRAINLRWSLDHFTQGEITNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSIDYSNTAWGSDVDFSVFQAQNVWIRTLYDRHRFVTRGT
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSIAPKYANGDLKGASKLITGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWESPVGPIKLDFAVPVADKDEHG
                     LQFYIGLGPEL"
     gene            34426..35064
                     /gene="msrA"
                     /locus_tag="ACHY1N_001070"
     CDS             34426..35064
                     /gene="msrA"
                     /locus_tag="ACHY1N_001070"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFS4043412.1"
                     /translation="MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGME
                     IAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYD
                     PSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAA
                     MLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA"
     gene            35387..36730
                     /gene="paeA"
                     /locus_tag="ACHY1N_001071"
     CDS             35387..36730
                     /gene="paeA"
                     /locus_tag="ACHY1N_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFS4043413.1"
                     /translation="MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINA
                     QRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSF
                     ILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANM
                     IFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTP
                     RENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA"
     gene            complement(36792..36998)
                     /gene="ytfK"
                     /locus_tag="ACHY1N_001072"
     CDS             complement(36792..36998)
                     /gene="ytfK"
                     /locus_tag="ACHY1N_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1107 domain-containing protein"
                     /protein_id="HFS4043414.1"
                     /translation="MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKV
                     KDKLHLSVMSEVNRQVMRLQTEMA"
     gene            37323..37880
                     /gene="ytfJ"
                     /locus_tag="ACHY1N_001073"
     CDS             37323..37880
                     /gene="ytfJ"
                     /locus_tag="ACHY1N_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001498728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HFS4043415.1"
                     /translation="MTLRKILALTCLLLPMMASAHQFETGQRVPPIGITDRGELVLDK
                     DQFSYKTWNSAQLVGKVRVLQHIAGRTSAKEKNATLIEAIKSAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSLESNKKLYPWSQFIVDSNGVARGAWQLDEKSSAVVVLDKDGRVQ
                     WAKDGALTQEEVQQVMDLLHKLINK"
     gene            complement(37870..38610)
                     /gene="cysQ"
                     /locus_tag="ACHY1N_001074"
     CDS             complement(37870..38610)
                     /gene="cysQ"
                     /locus_tag="ACHY1N_001074"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HFS4043416.1"
                     /translation="MLDQVCQLARNAGDAIMQVYDGTKPMDVVSKADNSPVTAADIAA
                     HTVIMDGLRTLTPDIPVLSEEDPPGWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIDHGKPILGVVYAPVMNVMYSAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHAD
                     AELKEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTNIWDTAAGHAVAAAAGA
                     HVHDWQGKPLDYTPRESFLNPGFRVSIY"
     gene            38800..40743
                     /gene="cpdB"
                     /locus_tag="ACHY1N_001075"
     CDS             38800..40743
                     /gene="cpdB"
                     /locus_tag="ACHY1N_001075"
                     /EC_number="3.1.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008663 - 2',3'-cyclic-nucleotide
                     2'-phosphodiesterase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2',3'-cyclic-nucleotide 2'-phosphodiesterase"
                     /protein_id="HFS4043417.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYMSAKGLKAGDVHPVYK
                     ALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDT
                     EVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGAD
                     VVVVLAHSGLSADPYKVMAENSVYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADIT
                     KGTLNGVPAVMPGMWGDHLGVVDLQLSNDSGKWQVTQAKAEARPIYDIANKKSLAAED
                     SKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKAS
                     GKEVKEWLECSAGQFNQIDPNSTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYD
                     GECQMINANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRSVLAAWIADESKRAGEIHPAADNNWRLAPIAGDKKLDIRFETSPSDKAAAFIKEKG
                     QYPMNKVATDDIGFAIYQVDLSK"
     gene            complement(40872..41252)
                     /gene="ytfH"
                     /locus_tag="ACHY1N_001076"
     CDS             complement(40872..41252)
                     /gene="ytfH"
                     /locus_tag="ACHY1N_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFS4043418.1"
                     /translation="MSQVSLSQQLKEGNLFAEQCPSREVLKHVTSRWGVLILVALREG
                     THRFSDLRRKIGGVSEKMLAQSLQALEQDGFLNRIAYPVVPPHVEYSLTPLGEQVSEK
                     VAALADWIELNLPEVLAVRDERAA"
     gene            41341..42200
                     /gene="qorB"
                     /locus_tag="ACHY1N_001077"
                     /pseudo
     CDS             41341..42200
                     /gene="qorB"
                     /locus_tag="ACHY1N_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418632.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
     gene            42309..43274
                     /gene="ytfF"
                     /locus_tag="ACHY1N_001078"
     CDS             42309..43274
                     /gene="ytfF"
                     /locus_tag="ACHY1N_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFS4043419.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLI
                     ALPIAWLGRVRLRQLARRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLP
                     VVIPVFANLLYSQRDGKLAWGKLAPALICIGIGLASVNIAELNHGLPDFDWARYTSGI
                     VLALVSVVCWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNTQ
                     TPDFSLPFGPRPLVFISLMIAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGL
                     LYTFLLRQQMPPLMTLSGIALLVIGVVIAVRAKPEKPLTESVSES"
     gene            43382..44044
                     /gene="ytfE"
                     /locus_tag="ACHY1N_001079"
     CDS             43382..44044
                     /gene="ytfE"
                     /locus_tag="ACHY1N_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HFS4043420.1"
                     /translation="MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARK
                     ELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVE
                     RVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEH
                     DEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALA
                     GE"
     gene            complement(44089..45501)
                     /gene="cycA"
                     /locus_tag="ACHY1N_001080"
                     /gene_synonym="dagA"
     CDS             complement(44089..45501)
                     /gene="cycA"
                     /locus_tag="ACHY1N_001080"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HFS4043421.1"
                     /translation="MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEM
                     EFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSV
                     VPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWF
                     IALGLGWLFIGKKRAAELRK"
     gene            complement(45810..46430)
                     /gene="fklB"
                     /locus_tag="ACHY1N_001081"
     CDS             complement(45810..46430)
                     /gene="fklB"
                     /locus_tag="ACHY1N_001081"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015742582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFS4043422.1"
                     /translation="MTTPTFDTIEAQASYGIGLQVGQQLSESGLEGLLPEALVAGIAD
                     ALEGKHPAVPVDVVHRALREIHERADAVRRQRFQAMAAEGVKYLEENAKKEGVNSTES
                     GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            46649..47287
                     /gene="ytfB"
                     /locus_tag="ACHY1N_001082"
     CDS             46649..47287
                     /gene="ytfB"
                     /locus_tag="ACHY1N_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418627.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YtfB"
                     /protein_id="HFS4043423.1"
                     /translation="MPGRFELKPTLEKVWHAPDNFRFMDPLPPMHRRGIIIAAIVLVV
                     GFLLPSDDTPNAPVVTREAQLDIQSQSQPPTEEQLRAQLVTPQNDPDQVAPVAPEPIQ
                     EGQPEEQPQTTQTQPFQPDSGIDNQWRSYRVEPGKTMAQLFRDHGLPATDVYAMAQVE
                     GAGKPLSNLQNGQMVKIRQNASGVVTGLTIDTGNNQQVLFTRQPDGSFIRAR"
     gene            complement(47271..47918)
                     /locus_tag="ACHY1N_001083"
     CDS             complement(47271..47918)
                     /locus_tag="ACHY1N_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709992.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4043424.1"
                     /translation="MYLDTSNVQSLKEKLLLCAVNEFAEYGYEGARVDNIVKAAGCSK
                     QTVYHHFGNKENLFIEVLEYTWNDIRQKEKALDFSDLPPQKAIEKIIDFTWDYYIANP
                     WFLKIVHSENQSKGVHYAKSQRLLEINHAHLQLMESLLDEGKKHNIFKPDIDPLQVNI
                     NIAALGGYYLINQHTLGLVYHISMVSPQALEARRKVIKETILSWLLVDPSSTAHE"
     gene            48131..48922
                     /locus_tag="ACHY1N_001084"
     CDS             48131..48922
                     /locus_tag="ACHY1N_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="HFS4043425.1"
                     /translation="MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDLPDADSVE
                     KLHITQQECIAEGVEVICFPADVGDLSLHEEMLDAAQNQWGRLDCLLNNAGISVKKRG
                     DLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
                     AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAK
                     GLVPWGRWGYPADIASTVRAMAEGKLIYTCGQAVAIDGGLSMPRF"
     gene            48932..49774
                     /locus_tag="ACHY1N_001085"
     CDS             48932..49774
                     /locus_tag="ACHY1N_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFS4043426.1"
                     /translation="MRDLLQRPDLFSINTATLGYKTPLPAIIDACAARGIGAIAPWRR
                     ELQGEDLQQIAHQLAASNMSVSGLCRSTYYTAPTLAERKLAIDDNRRALDDAAVLNAA
                     CYMQVVGGLPTGTKDLYEAREQVKQGIRQLLPHSKDVGVPIALEPLHPMTAADRSCLC
                     TLRQALDWCDELDPDGEFGLGVAVDVYHVWWDPDLASQILRAGKRILAFHVSDWLVPT
                     TDLVNDRGMPGDGVINIPSIRRLVENAGFNGAIELEIFSPYWWQKDINSTLDISVDRI
                     AHYC"
     gene            49784..50560
                     /locus_tag="ACHY1N_001086"
     CDS             49784..50560
                     /locus_tag="ACHY1N_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HFS4043427.1"
                     /translation="MSDQPVLFSRVAASCRLTLNREDKCHAINEEMIESLDHYLNEIE
                     NDTTLRLVELTATGDKFFCAGGDIKSWSAYSPLDMGRKWIKRGNDVFNRLRNLPQLTV
                     ANLNGHTIGGGIELALCCDIRIARPGAKFSNPEVMLGMVPGWMGIERVLNQVGPVVGR
                     QMLMLGKRLTAQEAQAANLIDEVVEKEQVESWMANQLAQLEKCGPVALAHIKQLILAL
                     ENKHADYPHQLLAGLMSATQDCQQATRAFAEKSSVSFHNQ"
     gene            50570..52111
                     /locus_tag="ACHY1N_001087"
     CDS             50570..52111
                     /locus_tag="ACHY1N_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HFS4043428.1"
                     /translation="MRKITTAEALAAQIQDGATIAISGNGGGMVEADHILAAIEARFL
                     QTGHPRDLTLIHSLGIGDRDCKGTNRFAHAEMLKRIIAGHFTWSPKMQALVKNNTIEA
                     YCFPGGVIQALLREIGAGRPGLFTHVGLGSFVDPRNGGGKSNECTTDDLVELIEIDGE
                     TKLRYRPFKVDYAILRGTYADPRGNVSLEEEAIDMDSYSMALAAHNSGGKVFVQVRDV
                     LEAGAIEPRRVKLPGILVDGIVEHREQPQTYLGGYDLTISGQHRRLSSNDAIELVSHP
                     VRRLIARRAARELVAGASTNFGFGIPGGIPGVALREGVPYQSLWLSVEQGVHNGMMLD
                     DAFFGCARNADAIIPSLDQFEFYSGGGIDITFLGMGEMDQYGNVNVSHLNGNLIGPGG
                     FLEIAQNARKVVFCGTFDAKGSKIDVTPDGLHITQSGQIPKLVTQVEKITFSAAYAQQ
                     SGQEVLYITERAVFQLTAEGVELIEIAPGVEIERDILPYMAFRPIIKHPRLMESSLFT
                     PMEDA"
     gene            52108..54189
                     /locus_tag="ACHY1N_001088"
     CDS             52108..54189
                     /locus_tag="ACHY1N_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005766390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HFS4043429.1"
                     /translation="MSQLDDTILDALTHVTFPKGFAQAEPAWVVTVDGVDYPLWQTDA
                     LVVGSGAAGLRAAVELKRRQQNVLIATAGLYMGTSACSGSDKQTLFTAATAGNGDNFT
                     KLAEALASGGAMDHDTAYVEAVGSLHTLGGLQYLGLELPEDRYGAILRYQTDHDEAGR
                     ATSCGPRTSRLMVKVLLEEVQRLAIPVLTSATVIKLLHQRDENGEDRVAGAILATGHR
                     AHNPWGLAIVTAPNVVLATGGPGELYRDSVYPHKCFGSLGLALEEGLTLTNLTESQFG
                     IGTPRSTFPWNLSGTYVQVIPYIYSVDAEGNEYNFLADYYRTTQELASNIFRKGYQWP
                     FHATRVMDFGSSLLDMAVAQEQQSGCQVFMDFNRNPEAVPGDLPFSLDRLDDDVRAYL
                     ENNDALAPSPIERLQRMNPLSISLYKMHGYDLTTQPLQFAMNNQHMNGGIEVDIWGQT
                     SLPGCFAVGEVAGTHGVTRPGGAALNAGQVFAVRLARFIGCTQKRNIDGDIAQLVAPT
                     LASIREIITQAHDNGTGMPLSVVREKIQARMSDHAGFICHADKVRRATRDALLLSEFV
                     QRHGLAIKHVGEVAELFMWRHMALTSAAVLTQLTHYIDAGGGSRGARIILDRDGNSIP
                     QTRNGFCDAWRFRSERTEDKKDKLLIHYCNGIFHVRETPVREFPIIRGIWFEKNWPGF
                     LNGTIYQPQDE"
     gene            54210..54686
                     /locus_tag="ACHY1N_001089"
     CDS             54210..54686
                     /locus_tag="ACHY1N_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012311688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFS4043430.1"
                     /translation="MRNIIRSINALLAALNITILAIIVACVTWQVAARFIFTSPSIFT
                     DELSRLLFICLGLFGGAYTAGQNRHLAIDLLPMMLKGKARRHLFLCIQIIVIIFATII
                     MVYGGGLLTMDTFDSGQTSPALGWQMGYIYMSIPISGVLIIIYTIDMVLTELKQPL"
     gene            54729..56030
                     /locus_tag="ACHY1N_001090"
     CDS             54729..56030
                     /locus_tag="ACHY1N_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFS4043431.1"
                     /translation="MDYWLPIIVLFGAFFFMLALGVPIVYAIGLSTLASISTQLDFNS
                     ALSVVSQKLASGLDSFTLLAIPFFILSGNIMNHGGIARRLINFARILGGRLPGSLAHC
                     NILANMLFGAISGSAVASAAAMGGVMHPQQVKEGYDPAFSTAVNVASAPTGLLIPPSN
                     TLIVYSLVSGGTSIAALFLAGYVPGILLGLALMVIAGIIAVRRGYPKPERPTLRQAGV
                     AIWMAIPSIFLIILIMGGVLSGIFTPTEASAIAVIYTLFLALVLYREISVKDLPKIFL
                     ESVITTAIVLLLIGSSMGMSWAMSNADVPFLILDLLNTISDNPIIILLIINIILLIIG
                     TFMDMTPAVLIFTPIFLPVVTELGMDPIHFGIVMVLNMCIGICTPPVGSVLFVGCSVS
                     KLPINKIIKPMLPFYAVMVLVLAMVTYIPQISMALPRALGY"
     gene            56083..57054
                     /locus_tag="ACHY1N_001091"
     CDS             56083..57054
                     /locus_tag="ACHY1N_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001422748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFS4043432.1"
                     /translation="MKIKVSAGIIGAVLMLSASQSWAVTLKLSHNQDKSHPVHKAMEF
                     FAKKSKEYSNGDITIRIYPNGTLGTQRETMELIRSGAIPLVKTNAAEMEAFENSYKLF
                     SLPYLFRDRDHYYQVMQGDIGRKILDSTKSKGYFGLTFYDGGARSFYGNKPVLKPDDL
                     KGMKVRVQPSPGAVEMIKVMGGNPTPLDYGELYTALQQGVVDMAENSVMALTTMRHGE
                     VAKSFSLDEHTMVPDVVLMSNAAFDKLSPENQAVILKAAKESMSYMKDLWSEEEKQEF
                     AKLDKMGVKVYQVDKAPFIEKVQPMYANFAKDNPALAPMLADIQAAK"
     gene            complement(57166..57615)
                     /gene="rplI"
                     /locus_tag="ACHY1N_001092"
     CDS             complement(57166..57615)
                     /gene="rplI"
                     /locus_tag="ACHY1N_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFS4043433.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNI
                     EFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE"
     gene            complement(57657..57884)
                     /gene="rpsR"
                     /locus_tag="ACHY1N_001093"
     CDS             complement(57657..57884)
                     /gene="rpsR"
                     /locus_tag="ACHY1N_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFS4043434.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            complement(57889..58203)
                     /gene="priB"
                     /locus_tag="ACHY1N_001094"
     CDS             complement(57889..58203)
                     /gene="priB"
                     /locus_tag="ACHY1N_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030894 - replisome [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HFS4043435.1"
                     /translation="MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            complement(58210..58605)
                     /gene="rpsF"
                     /locus_tag="ACHY1N_001095"
     CDS             complement(58210..58605)
                     /gene="rpsF"
                     /locus_tag="ACHY1N_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFS4043436.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDAEAGDSEE"
     gene            58932..59207
                     /gene="yjfY"
                     /locus_tag="ACHY1N_001096"
     CDS             58932..59207
                     /gene="yjfY"
                     /locus_tag="ACHY1N_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 family protein YjfY"
                     /protein_id="HFS4043437.1"
                     /translation="MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDMQSLGVIYIN
                     HNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR"
     gene            complement(59336..60022)
                     /gene="ulaF"
                     /locus_tag="ACHY1N_001097"
     CDS             complement(59336..60022)
                     /gene="ulaF"
                     /locus_tag="ACHY1N_001097"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase UlaF"
                     /protein_id="HFS4043438.1"
                     /translation="MQKLKQQVFEANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKADDMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAW
                     AQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGNAEPLHTP
                     GIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(60022..60876)
                     /gene="ulaE"
                     /locus_tag="ACHY1N_001098"
     CDS             complement(60022..60876)
                     /gene="ulaE"
                     /locus_tag="ACHY1N_001098"
                     /EC_number="5.1.3.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HFS4043439.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETD
                     ERLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMA
                     KAGMVEAA"
     gene            complement(60886..61536)
                     /gene="ulaD"
                     /locus_tag="ACHY1N_001099"
     CDS             complement(60886..61536)
                     /gene="ulaD"
                     /locus_tag="ACHY1N_001099"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFS4043440.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG"
     gene            complement(61550..62014)
                     /gene="ulaC"
                     /locus_tag="ACHY1N_001100"
     CDS             complement(61550..62014)
                     /gene="ulaC"
                     /locus_tag="ACHY1N_001100"
                     /EC_number="2.7.1.194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HFS4043441.1"
                     /translation="MKLRDSLAENKSIRLQAEAETWQDAVKIGVDLLVAADVVEPRYY
                     QAILDAVEQHGPYFVLAPGLAMPHGRPEEGVKKTGFALVTLKKPLEFNHEDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA"
     gene            complement(62024..62329)
                     /gene="ulaB"
                     /locus_tag="ACHY1N_001101"
     CDS             complement(62024..62329)
                     /gene="ulaB"
                     /locus_tag="ACHY1N_001101"
                     /EC_number="2.7.1.194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
                     /protein_id="HFS4043442.1"
                     /translation="MTVRILAVCGNGQGSSMIMKMKVDQFLTQSKIDHTVNSCAVGEY
                     KSELSNADIIIASTHIAGEISVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK"
     gene            complement(62345..63742)
                     /gene="ulaA"
                     /locus_tag="ACHY1N_001102"
     CDS             complement(62345..63742)
                     /gene="ulaA"
                     /locus_tag="ACHY1N_001102"
                     /EC_number="2.7.1.194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFS4043443.1"
                     /translation="MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKG
                     TIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIDRMGDAYN
                     WVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
                     CTAILVSLYWGITSNIMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVE
                     DLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVNWTVYILQTGFSF
                     AVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGT
                     IGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEI
                     FGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRAL
                     RAEEDAEKQLAEQSA"
     gene            64097..65161
                     /gene="ulaG"
                     /locus_tag="ACHY1N_001103"
     CDS             64097..65161
                     /gene="ulaG"
                     /locus_tag="ACHY1N_001103"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFS4043444.1"
                     /translation="MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVASGTFAMWWLG
                     CTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVL
                     DPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKER
                     CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPG
                     GSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKV
                     VIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHY
                     PRGFDDCFTIEPDLPFKSFL"
     gene            65269..66024
                     /gene="ulaR"
                     /locus_tag="ACHY1N_001104"
     CDS             65269..66024
                     /gene="ulaR"
                     /locus_tag="ACHY1N_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
                     /protein_id="HFS4043445.1"
                     /translation="MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLD
                     ESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCG
                     STAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
                     SLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLF
                     SRADQIDMLITGKNANPEILQQLEAQGVSILRV"
     gene            complement(66021..66770)
                     /gene="yjfP"
                     /locus_tag="ACHY1N_001105"
     CDS             complement(66021..66770)
                     /gene="yjfP"
                     /locus_tag="ACHY1N_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFS4043446.1"
                     /translation="MIEIESRELADIPVLHAYPVGQKDTPLPCVIFYHGFTSSSLVYS
                     YFAVALAQAGLRVIMPDAPDHGSRFSSDEARRLNQFWQILLQSMQEFTTLRAAIAEEN
                     WLLDDRLAVGGASMGAMTALGITARHPTVKCTASMMGSGYFTSLARSLFPPLIPETAA
                     QQNEFNNIIAPLAEWEATNHLEQLGDRPLLLWHGLDDDVVPADESLRLQQALSETGRD
                     KLLTCSWQPGVRHRITPEALDAAVTFFRQHL"
     gene            66952..67281
                     /gene="bsmA"
                     /locus_tag="ACHY1N_001106"
     CDS             66952..67281
                     /gene="bsmA"
                     /locus_tag="ACHY1N_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313192.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HFS4043447.1"
                     /translation="MVSRKRNSVIYRFASLLLVLMLSACSALQGTPQPAPPVTNHPQE
                     IRRDQTQGLQRIGSVSTMVRGSPDDALAEIRAKAVAAKADYYVVVMVDETIVTGQWYS
                     QAILYRK"
     gene            67430..67705
                     /gene="yjfN"
                     /locus_tag="ACHY1N_001107"
     CDS             67430..67705
                     /gene="yjfN"
                     /locus_tag="ACHY1N_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418609.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 family protease activator YjfN"
                     /protein_id="HFS4043448.1"
                     /translation="MKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVS
                     NISGDPQDVERIVALKADEQGASWYRIITMYEDQQPDNWRVQAILYA"
     gene            complement(67822..69447)
                     /gene="aidB"
                     /locus_tag="ACHY1N_001108"
     CDS             complement(67822..69447)
                     /gene="aidB"
                     /locus_tag="ACHY1N_001108"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418608.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HFS4043449.1"
                     /translation="MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLA
                     SIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVHN
                     LAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPL
                     LSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFS
                     VPQSDAHLVLAQTTGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA
                     IGWLLGQEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQ
                     PLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPF
                     VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLS
                     EAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKYASPPMAQ
                     AWCQVMLDTRGGVRLSEQIQNDLLLRATGGVCV"
     gene            complement(69531..70694)
                     /gene="yjfC"
                     /locus_tag="ACHY1N_001109"
     CDS             complement(69531..70694)
                     /gene="yjfC"
                     /locus_tag="ACHY1N_001109"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710049.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HFS4043450.1"
                     /translation="MLRHNVPVRRDLDQIAANNGFDFHIIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVDRAVKDEEILTQLAIPPLYWDVIAESWRARDPSLYGRM
                     DFAWCGNAPVKLLEYNADTPTSLYESAYFQWLWLEDARRSGIIPRDADQYNAIQERLI
                     SRFSELYSREPFYFCCCQDTDEDRTTVLYLQDCAQQAGQESRFIYIEDLGLGVGGVLT
                     DLDDNVIQRAFKLYPLEWMMRDDNGPLLCKRREQWVEPLWKSILSNKGLMPLLWRFFP
                     GHPNLLASWFEGEKSQIAAGESYVRKPIYSREGGNVTIFDGQNNVVDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIVDDEACGMGIREDNTLITKDTSRFVPHYIAG"
     gene            complement(70697..71335)
                     /gene="yjfM"
                     /locus_tag="ACHY1N_001110"
     CDS             complement(70697..71335)
                     /gene="yjfM"
                     /locus_tag="ACHY1N_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HFS4043451.1"
                     /translation="MARKRKSRNNSKIGHGAISRIGRPHNPFEPRRNRYAQKYLTLVL
                     MGGAVFLIVKGWSESGDVDNDGDGTFYSTVQDCIDDGNNADICARGWNNAKAAFYADV
                     PKNMTQQNCQSKYENCYYDNVEQSWIPVVSGFLLSRVIRKDRDEPFVYNSGGSSFASR
                     PVWRNTSGDYSWRSGSGKKESYSSGGFTTKKASTVSRGGYGRSSSARGHWGG"
     gene            complement(71345..71743)
                     /gene="yjfL"
                     /locus_tag="ACHY1N_001111"
     CDS             complement(71345..71743)
                     /gene="yjfL"
                     /locus_tag="ACHY1N_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HFS4043452.1"
                     /translation="MHILDSLLAFSAYFFIGVAMVIIFLFIYSKITPHNEWQLIKNNN
                     TAASLAFSGTLLGYVIPLSSAAINAVSIPDYFAWGGIALVIQLLVFAGVRLYMPALSE
                     KIINHNTAAGMFMGTAALAGGIFNAACMTW"
     gene            complement(71761..72420)
                     /gene="yjfK"
                     /locus_tag="ACHY1N_001112"
     CDS             complement(71761..72420)
                     /gene="yjfK"
                     /locus_tag="ACHY1N_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfK family protein"
                     /protein_id="HFS4043453.1"
                     /translation="MSGFFQRLFGKDNKPAIARGPLGLHLNSGFTLDTLAFRLLEDEL
                     LIALPGEEFTVAAVSHIDLGGGSQIFRYYTSGDEFLQINTTGGEDIDDIDDIKLFVYE
                     ESYGISKESHWREAINAKVMGAMILNWQEKRWQRFFNSEEPGNIEPVYMLEKVENQNH
                     AKWEVHNFTMGYQRQVTEDTYEYLLLNGEESFNDLGEPEWLFSRALGVDIPLTSLHII
                     G"
     gene            complement(72471..73169)
                     /gene="yjfJ"
                     /locus_tag="ACHY1N_001113"
     CDS             complement(72471..73169)
                     /gene="yjfJ"
                     /locus_tag="ACHY1N_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
                     /protein_id="HFS4043454.1"
                     /translation="MGILKSLFTLGKSFISQAEESIEETQGVRMLEQHIRDAKAELDK
                     AGKSRVDLLARVKLSHDKLKDLRERKASLEARALEALSKNVNPSLINEVAEEIARLEN
                     LITAEEQVLSNLEVSRDGVEKAVTATAQRIAQFEQQMEVVKATEAMQRAQQAVTTSTV
                     GASSSVSTAAESLKRLQTRQAERQARLDAAAQLEKVADGRDLDEKLAEAGIGGSNKSS
                     AQDVLARLQRQQGE"
     gene            complement(73188..73589)
                     /gene="yjfI"
                     /locus_tag="ACHY1N_001114"
     CDS             complement(73188..73589)
                     /gene="yjfI"
                     /locus_tag="ACHY1N_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2170 family protein"
                     /protein_id="HFS4043455.1"
                     /translation="MTWNPLALATALQTVPEQNIDVTNSESALIIKMNDYGDLQINIL
                     FTSRQMIIETFICPVSSISNPDEFNTFLLRNQKMMPLSSVGISSVQQEEYYIVFGALS
                     LKSSLEDILLEITSQVDNALDLAEITEEYSH"
     gene            complement(73716..74447)
                     /gene="rlmB"
                     /locus_tag="ACHY1N_001115"
     CDS             complement(73716..74447)
                     /gene="rlmB"
                     /locus_tag="ACHY1N_001115"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFS4043456.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIASLDQPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEAVRQRS"
     gene            complement(74627..77068)
                     /gene="rnr"
                     /locus_tag="ACHY1N_001116"
     CDS             complement(74627..77068)
                     /gene="rnr"
                     /locus_tag="ACHY1N_001116"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418600.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0016070 - RNA metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFS4043457.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVEL
                     HIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEA
                     GVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQG
                     DQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLTLHRAIKYLLSKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYY
                     RFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTARE
                     KAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIA
                     AATKAKRAAKKKVAE"
     gene            complement(77107..77532)
                     /gene="nsrR"
                     /locus_tag="ACHY1N_001117"
     CDS             complement(77107..77532)
                     /gene="nsrR"
                     /locus_tag="ACHY1N_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HFS4043458.1"
                     /translation="MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVK
                     IINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(77737..79035)
                     /gene="purA"
                     /locus_tag="ACHY1N_001118"
     CDS             complement(77737..79035)
                     /gene="purA"
                     /locus_tag="ACHY1N_001118"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFS4043459.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(79139..79336)
                     /gene="yjeT"
                     /locus_tag="ACHY1N_001119"
     CDS             complement(79139..79336)
                     /gene="yjeT"
                     /locus_tag="ACHY1N_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 domain-containing protein"
                     /protein_id="HFS4043460.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPKAWKKMISAMTNLPDNILRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(79418..80422)
                     /gene="hflC"
                     /locus_tag="ACHY1N_001120"
     CDS             complement(79418..80422)
                     /gene="hflC"
                     /locus_tag="ACHY1N_001120"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HFS4043461.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNK
                     PLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
                     "
     gene            complement(80425..81684)
                     /gene="hflK"
                     /locus_tag="ACHY1N_001121"
     CDS             complement(80425..81684)
                     /gene="hflK"
                     /locus_tag="ACHY1N_001121"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HFS4043462.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTNPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKV
                     LGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGTSNLLRLPPASSSTTSGASN
                     TSSTSQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(81770..83050)
                     /gene="hflX"
                     /locus_tag="ACHY1N_001122"
     CDS             complement(81770..83050)
                     /gene="hflX"
                     /locus_tag="ACHY1N_001122"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome rescue GTPase HflX"
                     /protein_id="HFS4043463.1"
                     /translation="MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQV
                     ITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQ
                     ATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEE
                     NKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI"
     gene            complement(83127..83435)
                     /gene="hfq"
                     /locus_tag="ACHY1N_001123"
     CDS             complement(83127..83435)
                     /gene="hfq"
                     /locus_tag="ACHY1N_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HFS4043464.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
                     "
     gene            complement(83521..84471)
                     /gene="miaA"
                     /locus_tag="ACHY1N_001124"
     CDS             complement(83521..84471)
                     /gene="miaA"
                     /locus_tag="ACHY1N_001124"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFS4043465.1"
                     /translation="MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSA
                     LIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATR
                     QLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG"
     gene            complement(84464..86311)
                     /gene="mutL"
                     /locus_tag="ACHY1N_001125"
     CDS             complement(84464..86311)
                     /gene="mutL"
                     /locus_tag="ACHY1N_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFS4043466.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDI
                     DIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQQEAWQAYAEGRDMNVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     LRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGT
                     AFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQL
                     ETPLPLDDEPQPAPRSIPENRVAAGRNHFAEPAAREPVAPRYTPAPASGSRPAAPWPN
                     AQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLE
                     RDGNISLLSLPVAERWLRQAQLTPGEAPVCAQPLLIPLRLKVSAEEKSALEKAQSALA
                     ELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLM
                     SEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE"
     gene            complement(86321..87658)
                     /gene="amiB"
                     /locus_tag="ACHY1N_001126"
     CDS             complement(86321..87658)
                     /gene="amiB"
                     /locus_tag="ACHY1N_001126"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HFS4043467.1"
                     /translation="MMYRIRNWLVATLLLLCTPVGAATLSDIQVSNGNQQARITLSFI
                     GDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDL
                     TENGKTEAVKRQNGSNYTVVFTINADAPPPPPPPPVVAKRVETPAVVAPRVSEPARNP
                     FKTESNRTTGVISSNTVTRPAARATANTGDKIIIAIDAGHGGQDPGAIGPGGTREKNV
                     TIAIARKLRTLLNDDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNR
                     SATGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQSDPYLSQAVLDLQF
                     GHSQRVGYDVATSMISQLQRIGEIHKRRPEHASLGVLRSPDIPSVLVETGFISNNSEE
                     RLLASDDYQQQLAEAIYKGLRNYFLAHPMQSAPQGATAQTASTVTTPDRTLPN"
     gene            complement(87677..88138)
                     /gene="tsaE"
                     /locus_tag="ACHY1N_001127"
     CDS             complement(87677..88138)
                     /gene="tsaE"
                     /locus_tag="ACHY1N_001127"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFS4043468.1"
                     /translation="MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG"
     gene            complement(88110..89657)
                     /gene="nnr"
                     /locus_tag="ACHY1N_001128"
     CDS             complement(88110..89657)
                     /gene="nnr"
                     /locus_tag="ACHY1N_001128"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052855 - ADP-dependent NAD(P)H-hydrate
                     dehydratase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HFS4043469.1"
                     /translation="MTDHTMKKNPVSIPHTVWHADDIRRGEREAADALGLTLYELMLR
                     AGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLATAVGIEVTLLAQESDKPLP
                     EEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLQQAPRESISQLIDHANSH
                     PAPIAAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLG
                     LDSWLAGQETKIQRFSAEQLSHWLKPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEA
                     ALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMDSLTESLEWADVVVIGPGLGQQE
                     WGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIES
                     DRLHCAKRLVQRYGGVAVLKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGA
                     LLGQKLSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQRIVNPEVTDKNHD
                     ESSNSAP"
     gene            89656..90795
                     /gene="queG"
                     /locus_tag="ACHY1N_001129"
     CDS             89656..90795
                     /gene="queG"
                     /locus_tag="ACHY1N_001129"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFS4043470.1"
                     /translation="MSEPLDLNQLAQKIKQWGLELGFQQVGITDTDLSESEPKLQAWL
                     DKQYHGEMDWMARHGMLRARPHELLPGTLRVISVRMNYLPANAAFASTLKNPKLGYVS
                     RYALGRDYHKLLRNRLKKLGEMIQQHCVSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLVDIPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGAIPEELRPLMGNRIYGCDDCQLICPWNRYSQLTTEEDFSPRKPLHAP
                     ELIELFAWSEEKFLKVTEGSAIRRIGHLRWLRNIAVALGNAPWDETILTALESRKGEH
                     PLLDEHIAWAIAQQIERRNACIVEVQLPKKQRLVRVIEKGLPRDA"
     gene            complement(90778..90831)
                     /locus_tag="ACHY1N_001130"
     CDS             complement(90778..90831)
                     /locus_tag="ACHY1N_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043471.1"
                     /translation="MRFYFYSQAVDESGVTR"
BASE COUNT        22134 a        24336 c        22659 g        21932 t
ORIGIN      
        1 aggtcatcta tttctttcag tatccctttt tcaccaagca agtatgaaat cgattcatta
       61 catacataag gcattaatag cagatgttct ttccttattg ctaataatgc attattcaat
      121 ggtttttcta ataaatccgt aatcgtagaa tcaactgaat ctttacaact cacctgcgag
      181 ttattcaagt cctgagaatt atttaactcc tgcggaatat ttaatagacg agctatttcc
      241 ttgttagctt cgcgttggta acacgccaga atcttgttag taatcaggtg taatgaactc
      301 tcatcttttc tttcaaagga cttcccttca taacgattag tcgaaccatc aggttgtgta
      361 aatataatga ctgtatgtcc ttcacgaatc ccattattaa aagctgaggc aagtgtaatt
      421 tctatttcca ccttagataa atccgctcgc tccccttcag gattattcat aacaaacttc
      481 attatctcac taccatcatt atttttgata taagatgagg acttaatatg agccatcata
      541 tttctacccg cttcgttgga gcgtttgcta aaatccacat aacccagggt aaatatctta
      601 gccaaaaact ccaaaaatgc tctgggagaa agaatattgc ttctgctatt ctgccctccg
      661 gcaattcggg caaaatcatt cattcccaca taccaggtat ctaagtcttc atttttttgt
      721 ttacaattgt cggctgatgt aatgttttga gaaaaattcc aacctgatat tttgctcatg
      781 acggactcct tgagttaata agaacgtcta agcattacaa attttactca caaaaaaata
      841 tcaaaaaacg ctcttttcac aaactcgccg taaatctgga gttatttacg gcgaaaagtc
      901 atcacgccat cagcatcttc actactgctt tgcgaacctg ggctggtgca cccactgcgc
      961 acagcggttt atgcacttcc cccggataaa acacaacaaa atcaccttca ttaaggataa
     1021 ctgttttctc atcaacgcct tccggcaaaa atgcgatgtc tttatcagct aaccagtcgg
     1081 tatccggcgt gcctgcaggt tgcgtgctga aggtcatgcc ttcctgacct tttaacacaa
     1141 tctgaatgtc gagatagcgg gcatggtact ccgcacggcg ggcttcgtac ggctcggtca
     1201 tatcttccga gataagataa aacagacgat tgccttcgat atcgtgcttg ccctttggcg
     1261 tttctgccgt aacgtgtgct ttgatatgct caatcgcctg gcgtaactcc tggggtagcc
     1321 acggctgaag attatgaata tttccgatga tcatcttttc cactccttaa ttaaaacaac
     1381 gtttcatttc tatcgttata cgaaaagatg atcaattccg ctagccttaa cgcgtgaatt
     1441 attgtcttat cacaacttat cggcaggcgc gttcccgcct ttcggatcaa ggccagcatc
     1501 actccttgag aagagttttt atcgcttccc ccgccagtgc agctgttgca cagagttgtt
     1561 cgattgagtg cccctcccgt gccttcgcag aaagccctga catcacggta ctcataaaat
     1621 cagtcacaca ttgtgcgctt tgtggatgcc gcctggcgat atagtcataa atggtcgttt
     1681 ctgcggcgtg ataatattga acggcaatat cacgcgctag tggatcatga ctatgaatac
     1741 cttcaagaac catacagcca gcgcagccgc cgttttggct atatctgcgc gccgcttctt
     1801 ttaatacctc aaccaggcac tcgcctactg gacgatcatc acgaagaata tcggcaagcg
     1861 gaatagcttc cgtaccgacg tattcattga gtacacggct aaataaccca gctttactgc
     1921 caaaagccgc gtagaggctc ggggggttaa taccaagata atcagtaact tcagcaacac
     1981 tgacagcatc gaaacctttt tggtgaaaaa gcacttttgc cgcagagatt gcctgctcag
     2041 gagcgaaacg tctgggacga cctggaacgc gagattgttt tttagtgacc attacaaaac
     2101 ctgttgacag aaagttaaaa cagttttgta atgcatgtta cataataaat caaggagtcc
     2161 ttatgggcgc ttttacaggt aagacagttc tcatcctcgg tggcagtcgt ggtatcggtg
     2221 ccgctatcgt acgtcgtttc gtcaccgatg gggccaatgt acgattcacc tatgcggggt
     2281 cgaaagatgc cgctaaacgc ctggcacaag agactggagc gacagcagta ttcacagata
     2341 gtgctgacag agacgctgtc attgatgtcg ttcgtaagag cggcgcattg gatatcctgg
     2401 tggtaaatgc aggtattggc gtctttggcg aggccctgga attaaatgcc gacgatattg
     2461 atcgcctttt caaaatcaat attcatgctc cttatcatgc ctctgttgaa gccgcccggc
     2521 agatgcccga aggcgggcgc atcttaatca tcggctccgt gaatggcgat cgtatgcctg
     2581 ttgcaggcat ggctgcttat gccgccagca aatctgccct gcaaggcatg gcgcgcgggc
     2641 tggcccgtga ttttggaccg cgtgggatca ccattaacgt cgtccagcca gggccaattg
     2701 ataccgacgc taatcccgcc aacgggccaa tgcgcgatat gttgcatagt ttgatggcta
     2761 tcaaaagaca tgggcaaccg gaagaggtcg ctggtatggt cgcatggtta gcagggccag
     2821 aagccagttt tgttaccggc gcgatgcata ccattgatgg cgcgtttggc gcataaccga
     2881 ctacgctcaa ttaagcccag ccattatcca tgatgtctgg gttttgttta ctcacgtcgt
     2941 ccgctaaaag cggctcccgg taaagagaaa tcttctgttc atgtcgtaaa tcttgaggat
     3001 aaccaaatgg tagaaagaac cgctgttttc cctgctggcc gacattcact atatgctgag
     3061 catcgttatt ctgcggctat tcgttccggc gatttgctgt ttgtttccgg gcaagtagga
     3121 agtcgagagg acggaacacc agaacccgat tttcagcaac aagtcagact ggcatttgat
     3181 aatttgcatg cgaccctggc agctgcggga tgcacttttg acgatatcat tgatgttacg
     3241 agcttccata ccgatccaga aaaccaattt gaagacatca tgacggtgaa aaatgaaata
     3301 tttagcgccc caccttatcc aaactggacg gcggtgggtg ttacatggct ggcaggcttt
     3361 gattttgaaa ttaaagtgat agcgcgcatc cctgagcagt aagcaatagt gttagccgtt
     3421 cgctttcaca ctccgcccta taagtcggat gaatggaata aaatgcatat ctgattgcgt
     3481 gaaagtgaaa aagaaaaaag cagggaatgt ctgcaattat tgataccgaa cgacagttcc
     3541 cctgcagaat cacatcaaat aaaaatgcat ataccttgac ttttaattca aataaaccgt
     3601 ttgcgctgac aaaatattgc atcaaatgct tgcgccgctt ctgacgatga gtataatgcc
     3661 ggacaatttg ccgggaggat gtatggttca gtgtgttcga cattttgtct taccgcgtct
     3721 gaaaaaagac gctggcctgc cgtttttctt cccgttgatc acccattccc agcccctcaa
     3781 tcgaggggct tttttttgcc caggcgtcag gagataaaag atggctaatc cgctatatca
     3841 gaaacatatc atttccataa acgaccttag tcgcgatgac cttaatctgg tgctggcgac
     3901 agcggcgaaa ctgaaagcaa acccgcaacc agagctgttg aagcacaaag tcattgccag
     3961 ctgtttcttc gaagcctcta cccgtacccg cctctctttc gaaacatcta tgcaccgcct
     4021 gggtgccagc gtggtgggct tctccgacag cgccaataca tcactgggta aaaagggcga
     4081 aacgctggcc gataccattt cggttatcag cacttacgtc gatgcgatag tgatgcgtca
     4141 tccgcaggaa ggtgcggcgc gcctggccac cgagttttca ggcaatgtac cggtactgaa
     4201 tgccggtgat ggctccaacc aacatccgac gcaaaccttg ctggacttat tcactattca
     4261 ggaaacccag gggcgtctgg acaatctcca cgtcgcaatg gttggtgacc tgaaatatgg
     4321 ccgcaccgtt cactccctga ctcaggcgtt agcgaagttc gacggcaacc gtttttactt
     4381 catcgcgccg gacgcgctgg caatgccgca atacattctg gatatgctcg atgaaaaagg
     4441 gatcgcatgg agtctgcaca gctctattga agaagtgatg gcggaagtag acatcctgta
     4501 catgacccgc gtgcaaaaag agcgtctgga cccgtccgag tacgccaacg tgaaagcgca
     4561 gtttgttctt cgcgccagcg atctccacaa cgccaaagcc aatatgaaag tgctgcatcc
     4621 gctgccgcgt gttgatgaga ttgcgacgga tgttgataaa acgccacacg cctggtactt
     4681 ccagcaggca ggcaacggga ttttcgctcg ccaggcgtta ctggcactgg ttctgaatcg
     4741 cgatctggta ctgtaagggg aaatagagat gacacacgat aataaattgc aggttgaagc
     4801 tattaaacgc ggcacggtaa ttgaccatat ccccgcccag atcggtttta agctgttgag
     4861 tctgttcaag ctgaccgaaa cggatcagcg catcaccatc ggtctgaact tgccttctgg
     4921 cgagatgggc cgcaaagatc tgatcaaaat cgaaaatacc tttttgagtg aagatcaggt
     4981 agatcaactg gcattgtatg cgccgcaagc cacggttaac cgtatcgaca actatgaagt
     5041 ggtgggtaaa tcgcgcccca gtctgccaga gcgcatcgac aatgtgctgg tctgcccgaa
     5101 cagcaactgt atcagccatg ccgaaccggt ttcttccagc tttgccgtgc gaaaacgcgc
     5161 caatgacatc gcgctcaaat gcaaatactg tgaaaaagag ttttcccata atgtggtgct
     5221 ggccaattaa ttgcggttgg taataaaagt ctggctccct ataatgagcc agacttttta
     5281 ccgctgtaat aaaggagaaa tcatgagcaa aactatcgcg acggaaaatg caccggcagc
     5341 tatcggtcct tacgtacagg gcgttgatct gggcaatatg atcatcacct ccggtcaaat
     5401 cccggtaaat ccgaaaacgg gcgaagtacc ggcagacgtc gctgcacagg cacgtcagtc
     5461 gctggataac gtaaaagcga tcgtcgaagc cgcaggcctg aaagtgggcg acatcgttaa
     5521 aaccaccgtg tttgtgaaag atctgaacga cttcgcaacc gttaatgcta cctacgaagc
     5581 cttcttcacc gaacacaatg ccaccttccc ggcacgttct tgcgttgaag ttgcccgtct
     5641 gccgaaagac gtgaagattg agatcgaagc gatcgctgtt cgtcgctaat atctactgaa
     5701 agataatcca ggtattgcgc ctgggttatc tgattcaacc acggagggtt gaagatggct
     5761 aaaccccgtt tcactaacga acaaattgct gaaattttac agcagtcaaa agagggggcg
     5821 tctaataagg agctatgtga acactatcaa tttagcgtta gcacgctgcg gcgctggcaa
     5881 gaacagcacg ctgacggcat cagaagcgaa ttaaaaaaaa cagaatccaa agcacaaatc
     5941 gtctttctgg ttttctttgc tatcgctatt ctactgactc ttatatttga caaacctaca
     6001 ggtggatggg taattccgcc tttattaatc tattgtgttt attatatccg ccagtatcgc
     6061 aacatctctg gcagacatat taaaaaagaa gatatctatc tctctcgttc agtaaataac
     6121 agctatagcg ccctttataa tttgagctgg acgtttattt gtttttttat ttttgcagta
     6181 atttattttt ttattcaggt gttttcgtaa aagactgacc tgaaagagta tttcaggcca
     6241 gcctcatcac ttgcttactg ccagccgtaa cgacggctat aaaatccttt caccaactgg
     6301 gttaacgtca tataccctgc caaaatcgca accagccacg ggaaatagct taacggcagc
     6361 gcctgcagct gcagataact ggccagcggt gaaaacggca atgcgatccc gacaatcatc
     6421 acgatcacgg tcatgatcat taacggccac gatgcacagc tctgaataaa cggcacacgg
     6481 cgggtgcgga tcatatgcac aatcagcgtt tgcgacagta agcccaccac aaaccatccc
     6541 gactggaaca gcgtttgcgt ttccggcgtg ttggcatgga atacccacca catcaggcaa
     6601 aacgtcagaa tatcgaagat cgagctgatc ggtccgaaga agatcataaa gcgccccaga
     6661 tccgccggat tccaacgctg cggcttttga atttgctcgt cgtcgacgtt atcaaacggg
     6721 atcgccacct gtgacacatc atacagcagg ttctgaataa gcaagtgtaa cggcaacatc
     6781 ggcaggaagg gcaagaaagc actcgccacc agcacgctga acacattacc gaagttggag
     6841 ctcgccgtca ttttgatgta tttcagcatg ttggcgaaag tgcgacgtcc ttcaataacc
     6901 ccctcttcca gcaccatcag gcttttttcc agcaggatga tatcagccgc ttcacgggca
     6961 atatctaccg cgccgtccac agaaatgccg atatccgcag cgcgtaaggc gggcgcatca
     7021 ttaataccat cgcccataaa gccaaccaca tgcccttcgc gcttcagtaa ggtcacaatg
     7081 cgttctttat gcatcggcgt caggcgggca aacagcgtgg tgcgctgtgc gagatttgcc
     7141 agttcgtcgt cagatagcgt ttcaatatca ctaccaatga ccacctctcc cgcgtccagc
     7201 cccacttcat ggcacacttt cgctgcaact aactcactgt cgccagtaag gatttttacg
     7261 gtgattccac tcgcttttaa tgccttcagt gccggagcgg ttgtctcttt tggcggatca
     7321 aggaaagcaa tatatccttc gaggatcagg tcggattcat ccgcccgctg gtaatctcct
     7381 tcacgcgctg gcaggtattt cgtcgccacc gcaaccacgc gcagcccctg acgattaagc
     7441 gtatcagtaa cccgcttaat cttacgcagc atgatgtcat cgagcggcac aatctcgcca
     7501 ttgtgacgca cctgcgaaca cacattgagg atttcctgca atgcaccttt gcaaaccagc
     7561 tgatggtgct cggtattttc tgccactacc accgacatcc ggcgacgctc gaaatcaaac
     7621 ggaatctcat caattttttg ccaacgactg gccagcgagc gcgctgactc ttcatccgta
     7681 ccttcgagca ccgctgtatc gagcaggttt ttaagtccgg tctgataatg actgttcaac
     7741 cacgcgctat gcagcacgcg ttcgctggtt ttaccggaga tatcggtatg attctccagc
     7801 acaattttgt cctgtgtcag ggtgccagtt ttatcagtgc acagaatatc cattgcgcca
     7861 aagttctgaa tagcatccag atgtttgacg atcactttct gtttcgacag ctttactgcg
     7921 ccgcgcgcca gcgtcgaggt aacaatcatc ggcaacattt ccggcgttaa gcctaccgcg
     7981 accgaaagcg caaacagtgc cgcttcccac cagtcgcctt tggtgtaacc attgattaac
     8041 agcaccaccg gagccatcac cagcataaag cgaatcagca gcatactgac gcggctgatc
     8101 ccttgctgaa aggcattcgg ctcgctttcc tgctcactaa cacgccccgc cagttgacca
     8161 aaccaggtat tggcacctgt agcaatcacc attgcttgtg cagtgccgct caccacggtg
     8221 gtgcccataa aacacagggt gtcacactcc agcggattgc tgtgctccgg ctggcgagtg
     8281 gtagcggctt tttctacggg cagagactca ccggttaacg acgcctgagc gacgaacaga
     8341 tcccgcgcct gcaagatacg taaatctgcc gggatcatat cccccgccgc cagttttatt
     8401 atatcgccgg gcaccagctg gtcgatcggg atctccagcc agccattttc gcctttgtcg
     8461 ttaattacgc gcagaaccgt cgctgtattg ctgaccatcg ctttcagggc atctgccgct
     8521 ttagtggaac gtgcttcctg aataaagttc agcaacgtag aaatagcgac cattagcgcg
     8581 ataacgcccg cggcaaataa atcttccgtg gcgtaagaaa tagcgccgag aatggtgagt
     8641 aaaatattaa aggggttgcg atagcagacc cataaatgta cccaccacgg cgacggttgt
     8701 tgtgcgggta atttattttc accatgttgt tcgcgggcag attccacttc cgcctgattt
     8761 aacccttccg gatgggtgtc gaacgttttc cataattctt cttcgggcat caccgccatt
     8821 ttcaggcaat gcgcacttaa ggacggcggg accgccgtat tcactgtctg ctgcgcgcca
     8881 ggcaatggat cgcgatgaac cagacgggaa ggtaaatggc gaatgagccg ggtaaaaatt
     8941 tctttaaaca taaggagtcc ctccgcactg tctgaaacag tacagaaatg tcttcaggcg
     9001 tggcgaagcc ttacctgaag gtaataaagc tgagcaggga cgttaaaacg tcacggcctt
     9061 acgcatccgg taacgccgtg aaaagacggg cttaccggaa aagttttaat ctccgtcgag
     9121 ggagaggcgt gggatcaggt tccatataac ctccggtaag tgaaaaaagc gccgcaaata
     9181 ataaggagaa tccaataata ttcgtagcat ctatggcgat ataatacctg ctggcaacta
     9241 aaccaacgat aaaccagact ttacccattg ctgaatgcac gggtaaagtt aggctcaaat
     9301 aattaaacaa cacgttacag gacaacagga tgcaaaatcg gctgaccatc aaagacatcg
     9361 cacgcttaag cggcgtgggg aaatctacag tttcccgggt gctgaataac gaaagcggcg
     9421 tgagccagcg cacccgcgag cgtgttgaag cagtgatgaa tcagcatgga ttttcccctt
     9481 cccgctctgc gcgcgctatg cgtgggcaaa gcgataaagt ggtcgccatc attgttaccc
     9541 gcctggattc gttgtcagaa aatctcgccg ttcaaaccat gctgccagcg ttctatgaac
     9601 aaggttacga cccaatcatg atggaaagtc agttttcccc gcaattagtt gccgaacatt
     9661 tgggggtgct gaaacggcgt aatatcgacg gcgtagtgct gttcggtttt actggcataa
     9721 cagaagaaat gttagcccac tggcagtcat cgctggttct gctggcgcgt gacgcaaaag
     9781 gttttgcttc ggtctgttat gacgacgaag gggcaatcaa gatcctgatg caacggctgt
     9841 atgaccaggg gcatcgtaat atcagttatc tcggcgtgcc gcatagtgac gtgacgaccg
     9901 ggaagcgacg tcacgaagcc tacctggcgt tctgcaaagc gcataaactg aatcccgttg
     9961 ccgctctgcc aggccttgct atgaagcaag gctatgagaa cgtagcaaaa gtgattacgc
    10021 ctgaaactac cgccttactg tgcgcaaccg acacgctggc acttggcgca agtaaatacc
    10081 tgcaagagca acgcatcgac accttgcaac tggcgagcgt cggtaatacg ccattaatga
    10141 aattccttca tccggagatc gtcaccgtag atcctggtta cgccgaagct ggacgccagg
    10201 cggcctgcca attgatcgca caggtaaccg ggcgcagcga accgcaacaa atcatcatcc
    10261 ccgccaccct gtcctgatcg tttcctgaac gataaattgt gatcttcgct gcgtttcggg
    10321 aacgttcccg tttttaaatt tttccgcgca atatattctg cagccaacca aaaatgtcat
    10381 ctgccatggg gctttatgat gagcaaaata aaccaaacgg atatcgatcg gttgattgaa
    10441 ctggtcggcg ggcgcggcaa tattgcgacg gtgagccact gtattactcg cctgcgcttt
    10501 gtcctcaacc aaccggccaa tgccagaccg aaagaaattg agcaactccc catggtgaaa
    10561 ggctgtttca ccaatgccgg gcaatttcag gtggtgattg gcaccaacgt gggtgattac
    10621 tatcaagcac taatagcgtc aaccggacag gcgcaggttg ataaagagca ggtaaaaaaa
    10681 gccgcccggc agaatatgaa atggcatgag cagttgatct ctcatttcgc ggagatcttc
    10741 ttcccgttgc tgcccgcgtt gattagcggc ggtttgatcc tcggttttcg taatgtgatc
    10801 ggcgatttgc ccatgagcaa cggtcaaacg ctggcgcaaa tgtacccttc cctgcaaacg
    10861 atctacgatt ttctgtggtt gatcggtgaa gcgatcttct tctacctgcc ggtcgggatt
    10921 tgctggtcag cggtgaaaaa aatgggcggc acgccgatcc ttggtatcgt gcttggcgtg
    10981 acactggttt ccccccagct gatgaacgct tatctgctcg ggcagcagct gccggaagtg
    11041 tgggactttg gcatgttcag catcgccaaa gtgggctatc aggcgcaggt gatcccggca
    11101 ctgttagccg ggctggcgct gggcgttatt gaaactcgcc ttaaacgcat cgtaccggat
    11161 tacctctatc tggtggtggt gcccgtctgt tcgctgatcc tcgcggtgtt cctcgcccat
    11221 gcgctgattg gtccgtttgg tcgcatgatt ggcgatggcg ttgcctttgc ggtacgtcac
    11281 ctgatgaccg gcagctttgc tccgattggt gcggcattgt ttggcttcct gtacgcgccg
    11341 ctggtgatca ccggcgtaca ccagaccacc cttgctattg atttgcagat gattcaaagc
    11401 atgggtggca cgccagtgtg gccgctgatt gcgctgtcga atatcgctca gggctccgcc
    11461 gtgataggca ttatcatttc cagccgcaag cacaatgaac gcgagatctc cgtgcctgcc
    11521 gctatctccg cctggcttgg ggtcactgag cctgcaatgt acggcatcaa cctgaaatat
    11581 cgcttcccga tgctgtgcgc gatgattggt tctggtctgg caggattact atgcggcctg
    11641 aacggcgtta tggcgaatgg tatcggcgta ggcggcctgc cgggaattct ctcgattcaa
    11701 ccgagctact ggcaggtatt tgcgctggca atggttatcg ccatcatcat cccgattgta
    11761 ctcacctcgt ttatctatca gcggaaatac cgcctgggca cgctggatat tgtttaattt
    11821 tcttcggggc gcaattgcgc cccctcgcat ttgcaggaat aacgtaatga ctaatcttcc
    11881 ccactggtgg caaaacggcg ttatctacca gatttatcca aagagttttc aggacaccac
    11941 gggtagcggc accggcgatt tacgtggcgt tatccaacgc ctggactatc tgcataaact
    12001 gggcgttgat gccatctggc taaccccctt ttatatctct ccccaggtcg ataacggtta
    12061 cgacgtagcg aactatacgg cgattgatcc cacctacggc acgctggacg attttgacga
    12121 actggtgacg caggcaaaat cgcgcgggat tcgtatcatt ctcgatatgg tgtttaacca
    12181 tacctctacc caacatgcct ggtttcgcga ggcgctgaac aaagaaagcc cttaccgcca
    12241 gttttatatc tggcgcgatg gcgaaccaga aacgccaccg aacaactggc gttcaaaatt
    12301 tggcggtagt gcgtggcgct ggcatgcgga aagcgaacag tactatttgc atctctttgc
    12361 accagaacag gcggatctca actgggagaa tccagcggta cgcgcagagc tgaaaaaagt
    12421 ctgtgaattc tgggccgatc gtggggtcga cgggttgcgc ctggatgtgg tgaatctgat
    12481 ctccaaagac ccgcgtttcc ctgaagacct ggatggcgac gggcgtcgct tttacaccga
    12541 cgggccacga gcacacgagt ttttgcacga gatgaaccgc gatgtgttta cgccacgcgg
    12601 gttaatgacc gtaggtgaaa tgtcctccac cagccttgag cattgccagc gatacgcggc
    12661 actgacaggc agtgaattgt cgatgacctt taattttcat cacctgaagg tcgattatcc
    12721 cggtggtgaa aaatggacgc tggctaaacc tgactttgtg gcgttgaaaa cattgttccg
    12781 ccactggcaa caaggaatgc acaacgtggc atggaatgcc ttgttctggt gtaaccacga
    12841 tcagccgcgc attatttctc gctttggtga tgaaggtgaa taccgcgtgc ctgcggcaaa
    12901 aatgctggcg atggtgctgc atggcatgca gggaacgccg tatatctacc aaggcgaaga
    12961 gattggcatg accaacccgc atttcacgcg cattactgac tatcgcgacg tggagagcct
    13021 caatatgttt gccgagctgc gcaacgatgg tcgtgatgcc gacgagttat tggcaatcct
    13081 cgccagtaaa tcccgtgaca acagccgcac gcccatgcaa tggagcaacg gcgataatgc
    13141 cgggtttacg gctggcgaac cgtggattgg cctgggcgat aactatcaac aaatcaacgt
    13201 agaagccgcg ctggccgatg actcctcggt gttttacacc taccaaaagt taatcgcact
    13261 gcgtaagcta gaagccatcc tgacatgggg caattaccag gatctgctgc caaacagccc
    13321 tgtattgtgg tgctatcgcc gtgaatggaa ggggcaaacc ttgctggtca ttgccaacct
    13381 tagccgtgag atccaaccct ggcagccagg gcaaatgcgc ggcaactggc agcttgtgat
    13441 gcataactac gaagaagcct caccacaacc ctgtgccatg actttacggc cttttgaggc
    13501 tgtctggtgg ttacagaagt aagtatccgc taagccccgg gaatgcctgt cattccgggg
    13561 ttttgtctgt cagcatgttg tttttgttga tttttcaacc agcaaattca ttaaaaaatt
    13621 tacataacgc tgtagcgccc gtcatccgta cgctctgctt tttactttga gctacatcaa
    13681 aaaaagttca aacatccttg atgcaaagca ctatatatag actttaaaat gcgtcccaac
    13741 ccaatatgtt gtattaatcg actataattg ctactacagc tccccacgaa aaaggtgcgg
    13801 cgttgtggat aagcggatgg cgattgcgga aagcaccgga aaacgaaacg aaaaaaccgg
    13861 aaaacgcctt tcccaatttc tgtggataac ctgttcttaa aaatatggag cgatcatgac
    13921 accgcatgtg atgaaacgag acggctgcaa agtgccgttt aaatcagagc gcatcaaaga
    13981 agcgattctg cgtgcagcta aagcagcgga agtcgatgat gccgattatt gcgccactgt
    14041 tgccgcggtt gtcagcgagc agatgcaggg ccgcaaccag gtggatatca acgagatcca
    14101 gaccgcagtt gaaaaccagc tgatgtcggg tccatacaaa caactggctc gtgcttacat
    14161 cgagtaccgt cacgatcgcg acattgaacg tgaaaaacgc ggtcgcctga accaggagat
    14221 ccgtggtctg gtcgagcaga ccaacgcctc gttactcaac gaaaacgcca acaaagacag
    14281 caaggtgatt ccaacccagc gcgacctgct ggccgggatc gtggctaaac actatgcacg
    14341 ccagcacctg ctgccgcgtg acgtggtgca ggcacatgag cgtggcgata ttcactatca
    14401 cgatctcgat tactcgccgt tcttcccgat gttcaactgc atgttgatcg acctgaaagg
    14461 catgctgacc cagggcttta aaatggggaa cgccgagatt gaaccgccga agtcgatctc
    14521 tacggcaacc gcggtaactg cgcagattat tgctcaggtc gccagccata tttatggcgg
    14581 caccaccatt aaccgtatcg atgaagtgct ggcgccgttt gttaccgcca gctacaacaa
    14641 acatcgcaag accgcagaag agtggaacat cccggacgcc gaaggctacg caaactctcg
    14701 taccatcaaa gagtgctacg atgccttcca gtcgctggag tacgaagtaa acaccctgca
    14761 caccgccaac ggtcagacgc cgtttgtaac ctttggtttt ggtctgggca ccagctggga
    14821 atcgcgcctg attcaggaat cgatcctgcg taaccgtatc gcaggcctcg gtaaaaaccg
    14881 taaaactgcg gtgttcccga aactggtgtt tgcgattcgc gatggcctga accataaaaa
    14941 aggcgatccg aactacgaca tcaaacagct ggcgctggag tgcgcaagca agcgcatgta
    15001 tccggatatc ctgaactacg atcaggtagt gaaagtcacc ggttcgttta aaaccccgat
    15061 gggctgccgc agcttcctcg gcgtgtggga aaatgaaaac ggcgagcaga tccacgatgg
    15121 tcgtaacaac ctcggcgtga tcagcctgaa cctgccgcgt attgctctgg aagcaaaagg
    15181 cgatgaagcc accttctgga agctgctgga tgaacgtctg gtgctggcac gtaaggcgct
    15241 gatgacccgt atcgctcgtc tcgaaggcgt gaaagcgcgc gtggccccga tcctctatat
    15301 ggaaggtgct tgtggcgtgc gtctgaatgc tgacgatgat gtttctgaaa tcttcaaaaa
    15361 cggtcgtgcg tctatttcgc tgggttacat cggcatccac gaaaccatta acgcgctgtt
    15421 cggcggcgag catgtatatg acaacgagca gcttcgcgcg aaaggtatcg ccattgttga
    15481 acgtctgcgt caggcagtgg atcagtggaa agaagaaacg ggttatggtt tcagtctcta
    15541 cagcacgccg agtgaaaacc tgtgcgaccg cttctgccgt ctcgatactg ctgagtttgg
    15601 cgtggtgccg ggcgtgaccg ataaaggtta ctacaccaac agtttccacc tcgatgtgga
    15661 gaagaaggtg aacccgtacg acaagatcga ctttgaagcg ccttacccgc cgctggcgaa
    15721 cggtggtttc atttgctacg gcgagtatcc aaacattcag cacaacctga aggcgctgga
    15781 agatgtctgg gattacagct atcagcatgt accgtattac ggcaccaata caccgattga
    15841 tgagtgctac gagtgtggct ttaccggtga gttcgagtgc accagcaaag gcttcacttg
    15901 cccgaaatgt ggtaaccatg acgcctcccg tgtgtcggta actcgccgcg tgtgcggata
    15961 tttaggtagc ccggatgcac gtccgtttaa cgctggtaag caggaagaag ttaagcgccg
    16021 cgttaaacat ttggggaatg ggcagatagg ttaatcttca ctctgcgcta agcaaatgcc
    16081 ggatgcggcg taaacgcctt atccggccta catttggcaa cggctgtagg cctgataaga
    16141 cgcgacagcg tcgcatcagg cattgattac cggatgcagc ctacacgcgg actgataagc
    16201 caggcgaaat aatgaattat catcagtact atcctgtcga catcgtcaac ggccccggca
    16261 ctcgctgcac cctgtttgtc tccgggtgtg ttcatgaatg ccccggttgc tataacaaaa
    16321 gcacatggcg ggtaaattct ggtcagctat ttaccaaagc aatggaagac cagatcatta
    16381 acgatctgaa tgacactcgt atcaaacgcc agggtatttc cctctccggc ggcgatccgc
    16441 tgcatccgca aaacgtgccg gatattctga aactggtaca acgcatccgc gccgagtgtc
    16501 cgggtaaaga catctgggtg tggacaggct ataaactcga cgaactcaac gctacgcaaa
    16561 tgcaggttgt tgatttgatt aacgtgctgg tcgacggcaa gtttgtgcag gatttaaaag
    16621 acccttccct gatctggcgc ggcagcagca atcaggtggt gcatcatttg cgatgataag
    16681 ttccctgtta cctgagtgca ggcaacaggg aaatgaggaa ttaacgatac ttctggtgat
    16741 aggcgttgcg ggtcgttttc agttgctctg cggcggcctg cgcttctttt actttacctt
    16801 catttgccag cttcagcgcg tcgtcaatct gaccgaccag aatgtcgaaa ccgtggcgga
    16861 aatctttcat ttccgggctg tccggtgatt tatcttcgag cttcggcggc gttgcttttt
    16921 gcgcatccag cgctgcggcg cgcatcatcg ttaacgcgtc tttgacttgc gccgcgttat
    16981 ccgctttttc gatcactttt aaattgtcgt tgagggtttc catattgtct tcaagatcag
    17041 cggcaaacga cgcagaactg aataccaacg aggagactgc aagaatagct aacaggcttt
    17101 tacgcattgc tcacttcctt ttttatttac acttcatcct tcacactgcc tcatcgacgg
    17161 ctacgctcat tcgcccgggt cacgtactgc gagtacgctc cccggccctc attcactttc
    17221 cgtctcgatg cagtgcgaat gattttgtgt aattttttag tttatagcgc ggcaggtcgc
    17281 gccagttttt tactgcccgg cgattttcat ctccggcaac agcacagaac cacactgtat
    17341 attactgcgt gtttcaatat cgttaccgac ggtgacaata ttgcgccaca tatcttttaa
    17401 attacctgcg atggtgattt cactaaccgg atactgaatt tcgccattct ctacccagaa
    17461 gcccgcagca ccacgggaat aatcaccagt aatggcactc acgccctggc ccatcagctc
    17521 cgtcaccacc agcccggtgc ccatctcttt gagcatttgt tcgaagctta gcccttgtcc
    17581 ggcaatccgc cagttgtgaa taccgcccgc atgtccggtg cttttcagcc ccagtttccg
    17641 cgccgagtag ctggtcagca gccactgagt caggatgcca tctttaataa tatcgcgacg
    17701 ctcggtgcgc acaccttcgc tgtcgaatgg cgtcgacgcc agccctttca gcagatgcgg
    17761 atgctcttca atggtcagcc agtccggcag aatttgttta cccagcgaat ccagcagaaa
    17821 ggtagattta cggtaaaccg agccacccgc tatcgccccc accagatggc caaaaagccc
    17881 ggttgccact tcattggcaa aaatgactgg cgctttcatg gtggagagtt tacgcggtga
    17941 caggcgcgat aaagtacggc gagcacagtc ggccccaacc cactctggcg tttgcagatc
    18001 gctcatcgca cgaccaatgg tgtaggcgta atcacgctcc atatcgccat tttcttcggc
    18061 aattacacag ctggagagtg aatgacgcgt agagcagtaa ccctgcaaca tgccgtggct
    18121 gttgccaaaa actttgacac cgtagtggct gttaaaactg ccgccttcgg tattggtaat
    18181 gcgtttgtcc gcctgcaatg ccgcctgttc tgcgcgggcc gccagttcaa tggcatcatc
    18241 cggggaaact tcagcagggt ggaacaagtc gagatctggt gcgtcaaagg ccagcagctc
    18301 tttgtctgcc aggccggcac agggatctgg cgaggtataa cgggcaatat ccagcgccgc
    18361 ctgtacagta cgggcaatgg cctgcgggct taaatcggtg gatgatgcgc tacctttgcg
    18421 gttctggtga taaacagtga tccccagcgc gccatcgcta ttgaattcaa cattctccac
    18481 ttcaccataa cgcgtgctta cgctaatgcc ggtggtcttg ctgacggcaa cttccgcacc
    18541 gtccgatttg cctgaggcca actccagcgc agtggaaact gcttcttcca gaatcttgcg
    18601 ctgcgcttca acttgagaga ttactttcat tgcaagtgcc ataatgtaga gagtttctct
    18661 gaagtctaac agagaaccgt ttttcagtgc gcatcttaac tggtaacatt agcctctttt
    18721 tttaaggagc ctgagatgac taagcagccc gaagactggc tcgacgacgt tcccggtgat
    18781 gacatcgaag acgaagacga tgaaattatc tgggtcagta aaagtgaaat taaacgtgat
    18841 gccgaggagc taaaacgcct tggcgcggaa attgttgatc tggggaaaaa cgcgctggat
    18901 aagatcccgt tagatgcgga tctgcgcgcg gctattgagc tcgcccagcg tattaagatg
    18961 gaaggtcgcc gccgccagtt gcagctcatc ggtaagatgc tgcgccagcg cgacgtagag
    19021 cctattcgtc aggcgctgga taagctgaaa aatcgccaca atcagcaggt ggtgctgttc
    19081 cataaactgg aaaacctgcg cgatcgtctg atcgatcaag gtgatgacgc catcgctgaa
    19141 gtattgaatc tgtggcccga tgccgatcgt cagcagctgc gtactctgat ccgtaacgcg
    19201 aagaaagaga aagaagggaa taagccgccg aaatccgcac gccagatttt ccagtatctg
    19261 cgcgaactgg cggagaatga agggtaattt tcgttgttga tgtgagtatg gtttgccgga
    19321 tgcggtgcac ctgtaggcct gataagacgc atcaagcgtc gcatcaggca ctatgctcaa
    19381 atgccggatg cggcgtgaac gccttatccg gcctacgcac actatatcag gctgaggccg
    19441 aattactgcg cggcttccgc cttcttcgcc agaccatcca gcagtttctg atggatgcca
    19501 ccaaaaccgc cgttgctcat gaccagaata tggtcgccag gctgagcggt tttcaccacc
    19561 atatctgcca gcgtatccac atcgccactc cagtgtgcag gctgaacgca ggcttctgcc
    19621 acttctgcca cctgccacgg aatatgcgcc ggttgcagca ggaagacttc atcggcacga
    19681 cctaatgaag gtgccagatc gtctttgcag atccccattt tcatggtatt tgagcgcggt
    19741 tccagcacag caataatgcg cgccgtacca ccaactttgc cacgcagcgc cgccagcgtt
    19801 gccagaatcg ccgtcgggtg atgggcaaaa tcgtcatata ccgtcacgcc attcgcttca
    19861 ccacgcaact ccagacggcg gcgagcgtta ataaacgaac ccagcgcgtt agcggcatct
    19921 gcaggcgcta caccaacatg gcgagccgct gcaatcgcca tcaggccatt gtgcatatta
    19981 tgttcgccta ccagcgacca tttcacttcg cccacttttt cgccatcaag caagacttcc
    20041 cattcggaag catcggtggt cagctttttc gcctgccagt gcccctgctc acccaccagc
    20101 tcctgctcgc tccagcagcc catcgccatg gtctgtttca ggttgatgtc attttccggc
    20161 cagataatac ggccctgccc cggaacgata cgcaccagat ggtggaactg tttctggatc
    20221 gctttcaggt cgtcaaagat atcggcgtga tcgaactcaa ggttgttgag gatcagcgta
    20281 cgcgggcagt aatggacaaa tttagagcgt ttgtcgaaga aggcgcagtc gtactcatcc
    20341 gcttcgataa caaagaagtc gctttcgccc agacgcgccg aaacctcaaa gttccccggc
    20401 acaccgccga ttacaaagcc cggtttgtaa ccacactgtt ccagaatcca ggtcgccatt
    20461 cccgcggtgg tggttttgcc gtgtgtacct gcaacggcca gcacccagcg gtcgcgcagc
    20521 acaaaatcgt gcagccactg tggacctgac atataaggga tgtttttttc cagtaccgct
    20581 tccacacacg gatttccacg ggtcatggcg ttgccaataa tcaccagatc cggctgcgga
    20641 tcgagctggc tggcatcgta accctgaatc agttcaatgc cttgcttctc aagtaaggtg
    20701 ctcatcggcg gatacacatt ggcgtccgaa cccgttactt catggcctaa ctggcgcgcc
    20761 agcatcgcca gaccgcccat aaacgtgcca caaattccta aaatatgaat gcgcatacgt
    20821 cactatcctt ttttaatctg ccgctcattt tacgcatatg tcgggcaagt gagaaacgca
    20881 tttcaggata atccgcaatt tgctggcgcg attcacctga gcgcaacatt ccgattattt
    20941 gttaagattg ttgcggtcgc tttactccat aaacattgca gggaaagttt tatgaaaacg
    21001 ttaggtgaat ttattgtcga aaagcagcac gagttttctc atgctaccgg tgagctcact
    21061 gctttgctgt cggcaataaa actgggcgcc aagattatcc atcgcgatat caacaaagca
    21121 ggactggttg atatcctggg tgccagcggt gctgagaacg tgcagggcga ggttcagcaa
    21181 aaactcgact tgttcgctaa tgaaaaactg aaagccgcac tgaaagcacg cgatatcgtt
    21241 gcgggcattg cctctgaaga agaagatgag attgtcgtct ttgaaggctg tgaacatgca
    21301 aaatacgtgg tgctgatgga cccactggat ggctcgtcca acatcgatgt taacgtctct
    21361 gtcggtacca ttttctccat ctaccgccgc gttacgcccg tcggcacgcc ggtaacggaa
    21421 gaagatttcc tccagcctgg taacaaacag gttgcggcag gttacgtggt atacggctcc
    21481 tctaccatgc tggtttacac caccggatgc ggtgttcacg cctttactta cgatccttcg
    21541 ctcggcgttt tctgcctgtg ccaggaacgg atgcgcttcc cggagaaagg caaaacctac
    21601 tccatcaacg aaggaaacta cattaagttt ccgaacgggg tgaaaaagta cattaaattc
    21661 tgccaggaag aagataagtc caccaaccgc ccgtatacct cacgttatat cggttcactg
    21721 gtcgcggatt tccaccgtaa cctgctgaaa ggcggtattt atctctaccc aagcaccgcc
    21781 agccacccgg acggtaaact gcgtttactg tatgagtgca acccgatggc attcctggcg
    21841 gaacaagcgg gcggtaaagc gagcgatggc aaagagcgta ttctggatat catcccggaa
    21901 accctgcacc agcgccgttc attctttgtc ggcaacgacc atatggttga agatgtcgaa
    21961 cgctttatcc gtgaattccc ggacgcgtaa tctcctgcgc ctctccacac ggagaggcgt
    22021 ttttatcgct gcgcaatgtt gactcttgtc actggcgaac tctgacgatt ctcccacagc
    22081 accgttaatc cacgctgtaa tgctataaaa ataaacaaca aaataccgat ggcgattttc
    22141 gtccaccatg agctcagcgt gccatcaaag tttatgtaag tctgaatcag tccctgaatc
    22201 gccacgccaa aaagcgtccc taataccgtt ccaacgccac cgctcaaaag cgtaccgcca
    22261 attaccactg aggcgatagc atccagttcc acacctacgc ccgccagcgc atatccggcc
    22321 tgggtataaa tcgagaagac aatccccgcc agcgttgcca gtccggtgga gagcatataa
    22381 atgcgaatag tggtgctgcg ggtagaaatc cccatcaggt ttgccgacgt tgcgttgccg
    22441 ccaatggcgt atacctgatt accaaaacgg gtacgatgcg cgaggaatat gccgataacc
    22501 accaccgcca gcatcagcag tcccatcgca cttaagcgac cgccgccagg gattttccac
    22561 gcaaggcttg agagcgtgtc ataaatggga tggtttatcg gaatcgactc ttccgaaacg
    22621 agatagctga cgccgcgcaa aaagaacatt cctgccaaag taatgataaa cgccgggatc
    22681 ttcagggcgt cgatcaaaag ccccataaat gcgccaaagg cacagcccat taccagcacc
    22741 agcggaaatg ccagcaacgg cgagaggccg aagtcgccaa tcacttttgc cagaaacacg
    22801 ccggtaaaag cgatcaccga accgacggag agatcgatcc caccggagag gatcacaaag
    22861 gtcatgccaa cggcaatgat cccaagaaag gcgttatcgg tcaggatatt gcagatcact
    22921 cttgtggaag caaaaccggg aaactgcgtc aggcagtaga gatagcccag cacaaagacg
    22981 ccgatggtga tcatcagtgg caaattacgt tttatcacgg ctacgtactc ctttaatcag
    23041 actgataaag cgttgcgact ggacaatcag cacacaaagc accaccaccg cttttacgac
    23101 ctggttcatc tccggcggaa agccagaaag taaaattccg gtattcattc cctgaataat
    23161 cagcgccccc accaccgaaa gtagcaggtt aaagcgcccg cccatcagcg atccgccgcc
    23221 aatcaccacc gcgagaatgg cgtccagctc cagccataac ccggcgttat tggcatcggc
    23281 accgcgaata tccgccgcca cgataatgcc cgcaatcgcc gcacatagcc cgctcaacac
    23341 gtaggtgagc atgacgatga ttcgcgtgtt taccccggca ttttttgccg cccgaatgtt
    23401 gataccaacg gcttcgataa acatccccag cgccgttttg cgggtcaaca gccagaacag
    23461 gagaagcgtc agcaccgcga taatgaccgg cgttggcagg aacaacagcg atccgctgcc
    23521 aaaccatgag agatccggcg agttaaacgt gacgatctgg ccggaggtga tcagttgcgc
    23581 cacgccgcgc ccggcgacca tcaggatcag ggtggcgaca aacggctgaa ttttgaggat
    23641 cgctaccagt atgccgttcc acaatcccgc caggatgccg gtgcccaggg cgcttaacaa
    23701 aacaatcggc aggctgaatc ccgcgaccgt catcgcagcc gttgtggctc cggcgatagc
    23761 catcaccgcc cctacggaga gatcaatccc accggtggcg atcaccagcg tcataccaat
    23821 cgccagtaac gcaacgggag ctgcacggtt aagaatgtcg atagggctac cgaacaaacg
    23881 cccatcctga agcaccacct gccagaaatg cggggctacc aggctatcga ccagcagcac
    23941 cagcaatagc gccgccagct gcgacattcc cgttggccag cgaaagcgcc ttttcggcgg
    24001 cgtagtgtcc gggagagatt gaggcatcac actgttctcc ttacgccgca atggcgttca
    24061 tgatcgccgg aacggaaagc tctgccagcg ggatctccgc cacctgtttg cgatcgcgca
    24121 tgataatcac ccgatcggca tagcccacca gctcttccag ttcagaggag atcaccagca
    24181 gcgccagacc atcggcgcat agcgtttcaa tcaggcggat gatctcggcg tgggcaccca
    24241 catcaatgcc gcgggttggc tcatcgagga tcagaaattg cggtcgggtc agtagccaac
    24301 gtgaaagcaa cactttttgc tgattgccgc cagagagaaa ttcaatcggt tgttcagttg
    24361 aaggtgtgcg aatgccaagc tggcggataa agcgttcggc aatctcttgc tgctctttgc
    24421 gggaaatggg tcgtagccag ccgcgctggg cctggagagc gaggatgata ttttcccgca
    24481 ccgaggcggc ggcgatgatg ccatcggttt tcctgtcttc cgggcagaat ccgatgccca
    24541 gtactgaagc ctgatgtggc gatcgcaggg tttgcggttt gcctttgatc aacgccgtgc
    24601 cgctgtcagc aggtttgata ccgaagatca cttcggcggt ttcggtacgt ccggatccca
    24661 gcaagccagc cagaccgacg atctcgccgg ggcgcacttc gagatcaaac ggtgctatcg
    24721 ttcctttttt gccgtaattt ttgaacgcgg caacgggttt gtcgctcaac aatgttcgcc
    24781 cggcacgctg tagcgcgtgg gtatccagct cgcgccccag catcattttt accagttcga
    24841 tctgcggtag ctcgcgcgtt tcccgacagc ctacgaaact gccgttgcgt aagacagtga
    24901 tccgatcgct gacctgatag acctgatcga gaaagtgagt gacaaagatc aggctgacgc
    24961 cgcgatcgcg caactgacgc atcaggccaa ataatagctc cacttcctgg gtgtcgaggc
    25021 tggcggtggg ttcatcgagg atcagcactt tggcggagag atcgatagcc cggcaaatgg
    25081 cgacgatttg ctgcatcgcg actgaaaagc ggttaagcgg ttcgcgcacg tcgaggaaga
    25141 aaccgtaaga tgccatcagt tcggtggcgc gcttttccat ctctttacgg cgtagaaggc
    25201 cgaaacgttt gggttcgcga cctatgaata gattatcagc aaccgacata ttgggtagca
    25261 ggttgacttc ctgatagacg gtgccgatac cgagttgttg tgcatgggcg gtatttttcg
    25321 gtgagatagc ctggccttcc agccagatgg tgccgcgatc ggcgtggtat acaccagtta
    25381 atgctttgat tagcgttgat tttcccgccc cgttttcacc aagcagcgcc atgatttcgc
    25441 cacggcgcag gctgaaatca acgttgtcta acgctttgac gccggggaaa aatttactta
    25501 atccttcggt gcggaggatc tcctggtgtt ggtcggtcgt catggtttcc cccggtgtaa
    25561 agcgtgctcc cagtaggcat gataagacgc ggtaagcgtc gcatcaggct tcagcgcacc
    25621 accgccggat gcggcgcgag cgccttatcc ggcctacgaa tcggcatcag gcatagcaac
    25681 cctcaatacc ccatattttt cttcttctct aactcttctt ttgcggtatc aggcagataa
    25741 agggtggatt tggtcagggt cagcttttca ggcatggtgc cgtctttttt gtatttctcc
    25801 agcgcatcga aagcgggacc tgccatattc ggcgtcagtt caacactggc gttcgcttcg
    25861 ccatcaatca tcgctttgta gatatccggt acaccgtcaa tggaacccgt gaggatatct
    25921 ttgcccggtt tcaggcccgc ttctttaatt gcctgaattg cgccaatcac catgtcatcg
    25981 ttatgggcgt aaaccatgca gatgtttttg ccgttgtttt ccgctttgat aaagctctcc
    26041 atgacttctt tgcctttact gcgggtgaag tcacctgact gcgagcggat aattttgata
    26101 tttggcgcat tcttaatggc ttcggcaaag cctttcttac ggtcaatggc gacgctggcc
    26161 ccaacggtgc cctgcagctc caccacgttg catggtttgc cattcacttc ttttaccagc
    26221 cagtcaccga tcaacttacc ttcgaggatg ttgtcggcag taacggtggt catatagagc
    26281 gatttgtctt tcacatcgat ggaacggtcg agcaagaaga ccgggatttc ggcatctttc
    26341 gcctctttta ataccggttc ccaacctgtc gcgaccaccg gagcgataaa gatcgcatcc
    26401 accccttgtg caacgaagga acgtaccgct ttaatctggt tttcctgctt ttgctgacca
    26461 tcggcaattt tcagcgtaat tccgcgtttt tcggcctcac ttttcgccac attggtttct
    26521 gcggcgcgcc agccggattc cgatccgacc tgcgaaaatc ctacggttaa tggagcggcc
    26581 aacgccatag acgacatggc tgccgagact gcagagacta caagtaaacg tttccacata
    26641 gggttgtcct cgtcggggta gttattattg gttaaaagat gttcgcgaaa aaactataga
    26701 caatcggtga tgtaacgaat tgcgttacat cacacttcaa aaaagtaaat aaaacgttaa
    26761 tcacaagttt gtaatcgctt tcatctcact atgaaaaatg cggctacggt tatggatttt
    26821 cctgctctgc ataccgtctt aaaactggcg aaaaaggaaa atgaagacga aaacaagcga
    26881 agacattcgg cgcgagttgg ctataatact cggcacttgt ttgccacata tttttaaagg
    26941 aaacagacat gagcttactc aacgtccctg cgggtaaaga tctgccggaa gacatctacg
    27001 tggttattga gatcccggct aacgcagatc cgatcaaata cgaaatcgac aaagagagcg
    27061 gcgcactgtt cgttgaccgc ttcatgtcca ccgcgatgtt ctatccgtgc aactacggtt
    27121 acatcaacca caccctgtct ctggacggtg acccggttga cgtactggtc ccgactccgt
    27181 acccgctgca gccgggttct gtgatccgtt gccgtccggt tggcgttctg aaaatgaccg
    27241 acgaagccgg tgaagatgcg aaactgattg ctgttccgca caccaagctg agcaaagaat
    27301 acgatcacat taaagacgtt aacgatctgc cagagctgct gaaagcgcag atcgctcact
    27361 tcttcgagca ctacaaagac ctcgaaaaag gcaagtgggt gaaagttgaa ggttgggaaa
    27421 acgcagaagc cgctaaagct gaaatcgttg cctccttcga gcgcgcaaag aataaataag
    27481 ttcttctggc gcaataaccc tgaacaccgg gcttcggtta gtaagggttt ttttatgccc
    27541 gcgataaata aacacacctt attccaccac cgcctgcaag cgtaataacg cctcttccac
    27601 cacctcatcc gcagccagac caatacgctt tgccagccgg gcgcgtagat ccatcatccg
    27661 cacctgattc accagcacca cgccgtgcac atcgccttct tcgcaatgta aaggaacgct
    27721 aaatccggca taacgggcaa aatttccgcc ctgcgtaatg ggggccacca gcgtcattcc
    27781 cagttgatta aaggcttgaa cggagagcac aagcgcaggt cgaccagcac cttgctgttc
    27841 atggccgctt gctggatcaa agccaaccag cacaatgtct ccccgttcaa attcactttt
    27901 ctttaccata tttcgtcacc cgcaggggtg gatttacccc agacatcctg ctcgctaagt
    27961 tccgcggcgt tcatgtcaca ctgtgccagc agttcatcaa gcgagtagcg cctggagatg
    28021 ggtgtcagaa tcagttggtt gttgctcacc tgcgcttcca cgctctgccc cggctgtaag
    28081 ttaagttctt tcattacgat attgggaatg accatacctg cactgttccc ccatcttttt
    28141 atggtaatac gcatctgcac ctccttaagt tatacaaagt ataactcacg gtgctacagg
    28201 aaacgtttta cccctgcaca tttgtgaacg ccagcagagt tttttatgcg attgcagata
    28261 tggaaagcgg ctcggagaga aaagcaaaag atggaaaagt tacaaaaaaa aatcgcgaga
    28321 tacatcgcat aaaacaacgc cacccgaagg tggcgtgctt ttattattac ttatccctgt
    28381 ctaaccagtc gccgctttca attagcttta atccatcgac gggtcgttga taaacgtaca
    28441 tccatgcact cccgtacggc gtctgaatca actggcgcgc gtattcaccg cccctggtgc
    28501 gcaaggcatc aagttcggcc agcgtggcgt tgtcaatacg ataaacttca ccgtgtactg
    28561 ttccgttccc cggaactgcg cctggatagt ggcccaggct atacaactgg tagttatcga
    28621 tactgaaatc gcccagtaac tgggcattgg tcatccagtg actgttgcct tgtttgtggc
    28681 gtaaactgcc gtagacaaat attcgcattg ctaaaactcg aactgataga gcaaatccag
    28741 tgcctggtct acaccagaca cggcttccag atatagctta ggcatcaggc gataacgtaa
    28801 cgtgagtgtt gctatagagt caaatatacc cacgccgtat ttcacttgca gacctggcaa
    28861 tacatagccg ctgaccacta cctgggagga gtcgcctact ccctgggtgt cgagcgctaa
    28921 attgcttacg ccaaacgtct cgccgatttt acccacaatc tggccacttt gcgcaacccc
    28981 caggccaatc agcattgagg tcatcgccgc actgtcgctc tgatcgctct ccagcccttg
    29041 tccacgtagc aaataagaca atgcagcttg ttgcgacata gccgggtcag agaagatctc
    29101 cgctttcggt tcgtccgcca gaccagtgac gcgaactccg gcgattacgt cgtcttctgt
    29161 agcatccggg ttacgaatag cttcaatatt aagatacggt tgatctggcg gaccagagaa
    29221 cagtagctca cccttacgca caatcagatc ctgaccatag gcatggaagc gcccttcagg
    29281 gatgttgatc tgcccgttca ggcccagccc ttgtttgtcc tgaacgacgt taagatcgcc
    29341 cgtcagccgc gctttcaggc caaaggcgtc aatgcgcaca ttgttgccaa cgtggacaat
    29401 caggttactg ttaatcggaa tcgacgccgt tttcggctct tccggttgca ggttatcgtt
    29461 aagcatcacc acatcgctgg agacgcctac tgcgctttcc ggcagatcgt gcaccacgat
    29521 gcgcgcccac gggacatcca cgcgaccatc gagggtaaac aggtttggtg tagcctcgaa
    29581 tacaacatct ggcgatacat ccattcgtac catcggcggc acggtgatcc gcactttact
    29641 gcctttcgcc gttactcgtg cccgccagtt ttcaatttgg ctccagtcgg catcaccgtt
    29701 caggtagatt tcaccctgct gggtccgtac ggtaccggca agcgtcgagc gcataccgtt
    29761 aaagttgacc gcaagctggc tcggctgcat atcaaacggc ataaagttgc cgtcgatatc
    29821 cacacccgta acctgaagct gaccaaacaa ctgcgggctt tgcacatcac cacccagacg
    29881 caagttggca ctcaccatcc ccgctgcttt ttccccacgg gtaaagatgg ggtttatcat
    29941 cgcaaggttg aagttacgga tattgacgtt gccaccaaga ttacggcggc cttgcggatc
    30001 ggtcacctgc acctgtccat caaactggcc gttattggtc aggcggatgg tccagcccaa
    30061 ttcggcacgg ttgttacgca attccgccgt cagattcagt gtctgaaacg ccaccggcag
    30121 cgccgcatcg ttgacggttt gcgttacctg cacgttacgc cccgaaaggg tgatactgcc
    30181 ctgcggcagc ccctctttcg tggtgtccca ggcaacatcc gctttacccg tgaagatacc
    30241 gctggcctga gtggtttctg gcataaacgg tttcagcatg gcgaggtcga agcggttgag
    30301 attcaccacc gcacgccctt cggcccccgc atcgatagtt tgcggcacgc acagttccgc
    30361 attcgggtta agccagcagt gtggcccgat gctgattttt tgctccttat tgcggtaatc
    30421 cagcgcaata tcgcgggtca gcgaccacgg gccgaccggc gtctggaagc gggtattgct
    30481 aagagttccc ttccagcgtt cttctttgcg atcaaaactt cctgccagat taagctgccc
    30541 ggaaaccggc tcgccctgaa tccgcaactg tagctcgtgc tgcttttcgc tgcctttggc
    30601 attcagggtg acgaggttga tatttacatc cggctgcgaa atttgctcaa cgcgtacgtc
    30661 gagtttcccg gcgatctgat cggtggattt aatgtcgcct tccacgcgaa cctgcgtcac
    30721 ggaaagttcc tgccagcgca ggccgcgcgc ggtgatatct gccagtagtt gtggcgcttc
    30781 caccgtgccg cgtactttca ccagcccttt cgctgtaccg ccaagccccg gcagcgcgtt
    30841 atccagcccc ggcgcgttga tggtggcatc aagattgaga tcttttaccc ccagctcgcc
    30901 tttcacttcg gcactgtttg gccccagttc cagatgaagc cctgggatca tccactgcat
    30961 ataactgttg cctttcagcg tgccgtcaac gttcactttg ttctgtttga cgttaccggt
    31021 cagcttcagt tctggcacct ccatctgcca ggtgccgccg tacaggctac cgcgggtttt
    31081 aatcaagcca ttgagtttcg acggccactc cgggatctct ttggcggtgt taatgccgtt
    31141 aagcgttagc tcaccgcgcc aactaatggc ctgctgccag tcgagcaacg ccttgagttc
    31201 agttttccct tccagcgccg cgacggtgag tttgtcgaga ttgacctgct gttcattacc
    31261 tttggcatca agggtaatgg tggctggcgg gatctccagt cccttcactg ccgtacgcat
    31321 agagagcgtg taatcggtca ttttgccggt aagtttcagt ttcagatcat ccgcctgata
    31381 ctgcttctca ccggtgaacg gccagtaaag ctgtttgctg ttcacttcca cgttgagtgg
    31441 caatccggct tccgccagtc gcgtctgggc gcgtaaatcc atatccaccg gaccggaaag
    31501 gttaacgcca atctccagct gttcgcgcag cgcaccgccc actttcagct tcagtttttc
    31561 tcctttcaac ggctccacgt ttagtgtgca gttgagggtg atatccaccg gccagttgtc
    31621 tgacagctgc gccgtgccgc tggcgttgac gatcccttga ctggaatcga tatccagggc
    31681 gtccagttta gtattgccgt caatgctgct cactttcagc agcatggtgc gcacggtgat
    31741 gtccgtgtcg cccgtcacgc gtaactgctc gcctttaaac tcttcaatgt tcaggttaag
    31801 cggcaaatgc acgtcggtca tttccggcaa taccgggcga gaaaagagat ctttcagcgt
    31861 ttcgccgagc ggcttttcct ccggctgcgg attttcaatt ttcggttcga ccacttcttc
    31921 ctgcgccact tccgccactt tcggcagagc aatcagcagg cctttcagcg acgtcggttt
    31981 cagggtcagg gttttctcct gccagttcag gccggaggtg aagtccatca ccgacaccgt
    32041 ggtgtcatca atcttgatgt tgacgttgtc cagcgccacc cgtgtcaggg tgatgggata
    32101 cggcgtggag agatccagcg gaccgctatc ttcctcttct tcaacctgtt cagaaggagg
    32161 cattttttta ctgtcgatgt tgacctgaat gtctttcagc gccaggtcat taatacaaac
    32221 gctactgttc cacaggcact caagaccgac cgccagatgc agattacccg cttttaccgc
    32281 cacgcctggc tgctcataac gaacgtcaga caaggtgaga tcgcgccagc cgccggtgac
    32341 cttgccaata tccagtcctg gcacccagcg ttccgccgct ttaaatacaa gatgcaggcc
    32401 gctggtggtg cccaccagaa acgccaccga tcccagcaac agtaagataa cgataaccac
    32461 gccgaggctg atttttttcc ataaactcat aattctggcc ccagaccgat gtaaaactgt
    32521 aacccgtgtt cgtctttatc cgcgaccggt acggcaaaat cgagtttgat tggcccgacc
    32581 ggcgattccc agcgcacgcc gaccccggta ccggttttaa agtcgctgcg gcgaatatcg
    32641 cttaccgctt cgccactatc gacaaacacc gcgccccacc attttccggt cacgttgtac
    32701 tggtattcca gcgatccggt tatcaacttc gaggcccctt tcaggtcacc gttggcgtat
    32761 ttcggggcga tagatttgta tttgtagccg cgaatactgc gatcgccccc ggcgaagaaa
    32821 cgcagatccg gcggtacttt gtcgaaatca ccggtttcaa tccagcccag cgtgccgcgt
    32881 gtaacgaaac gatggcgatc gtacagtgtg cggatccaga cgttctgcgc ctggaaaacg
    32941 gagaaatcga catctgaacc ccaggccgtg ttggagtagt cgatagagta gcgttgcgag
    33001 tcgccccagg ttggcatcag gccaccacga gaacgcgtgc ggctaatcat caccccagga
    33061 taaaacagca tcgtggtgtt ggtaatttca ccctgggtaa agtggtcgag gctccagcgc
    33121 aggttaatgg cacgctgcca gccgctggag agatcccagt agcgagaagc caccagcgta
    33181 gtggagtcag attcggtatc gttcaggtca gtgcgcttaa aaccgccctg caccaaataa
    33241 tattgttcca gtggattctt cagcagcggc attttatagc tgaagtcgag ggtctgttcc
    33301 ggcgcggaaa tactggtact ggtggtcaga ctgtgaccat aagagttcat ccacggcttt
    33361 ttccacgtcg ctttcacgcg cggtcccaca tccgtagagt aaccgacccc ggtttcgatg
    33421 gtgttttcag ttcgcggcga aaccacgccc gtcaagggta atactttcgt ttcgcgcgct
    33481 ttatcaaatt gtggagccac caccaccgag ttaaaccagc cggtagcaga aagtcggcgg
    33541 ttcagttccg ccagatcttt cgattcgtac tcatcgccct ctttaaacgg caccagattt
    33601 tgcaggtatt catcgcggat ttgtgatcct tcaaaggtca catgcccaaa gcggtaacgt
    33661 tcgccactgt tataatcaat atcccagaag gctttatgca ggccgagcgc aatgcccagc
    33721 tgcgctttgg taaattcgct atcgaaataa cctttacgca acgcaatgct ggttaaggac
    33781 tttttgaaat tttcataatc gccctggttc agcaccgtgc caatagccgg gcgagtatcg
    33841 agcaatttca aatagtcttt atcggtccgc gcgccgccgc gcaataccac atcggtgccg
    33901 ccaattaaca ccggcacacc tggcgtgact ttggcgatca atacctgccg ccctttcttt
    33961 ggcggtggac ggagatcaaa ttcaatggtc ggctggtaat aacccagcgc tttcagacct
    34021 tcgcggatgg catcatcgac gcgtgcgcga aagcgacggt ctggcgtcac ttcatcactt
    34081 tcaatcgtag aaagctgcgc acgaacgttc ttttccagct gtcccgataa cccctcgacc
    34141 tgtagacgga cgttcgcggc gacggcagat ccgcttaagc agagtaagct tacacagcat
    34201 aactgtcgga tatagcgcac attttctcct gaatatcctt ttttcctgcc cctggaacgc
    34261 cgttaaacgg cttaacaaaa atccagtaat atggattaaa aagcagacta aaccccaaat
    34321 atttcttatg ttttacttta gacctattca cggtggttat tgtgtgcaaa tacgcctctt
    34381 gttacaacct taaccccaat gaccgatttt cgggagagcg acaccatgag tttatttgat
    34441 aaaaagcatc tggtttcccc cgccgatgcc ctgcctggac gtaacacccc gatgcccgta
    34501 gccacgctgc atgcggtcaa cggtcactca atgaccaatg tacctgacgg aatggagatt
    34561 gccatttttg cgatgggttg tttctgggga gtggagcgtc tgttctggca gttacccggc
    34621 gtttacagca ccgccgcagg ctataccgga ggctatacgc caaatccgac ttatcgggaa
    34681 gtgtgctccg gtgatacggg tcatgccgaa gcggtacgca ttgtttacga tccttccgtc
    34741 atcagctatg agcagttgct acaggtattt tgggagaatc acgatcccgc ccagggaatg
    34801 cgtcagggca atgaccacgg cacgcagtat cgttcagcga tttatccgct gaccccagaa
    34861 caggatgccg cagctcgcgc cagtctggaa cgttttcagg cggcgatgct tgccgccgat
    34921 gacgatcgtc acatcaccac ggaaatcgct aacgccacac cgttttatta tgccgaagat
    34981 gaccaccagc aatatctgca taaaaacccg tatggttact gtggaattgg cggaattggc
    35041 gtctgtctgc caccggaagc atagcgttac gggtacaaat gtagattgtt gataaagtgc
    35101 tctttgtcta tgccggatgc ggcgtgaatg ccttaccagg cctacaaaat cgtccaaatt
    35161 caatatattg cagggactgc gtaggcctga tcggcatagc gcatcaggca gtattgcatt
    35221 tatcagcagt ctgaatttta accctctggc gactttacag taccttacgc tatactagcc
    35281 actgaaaatg ccggttcact ttcttcgaat cggctttcaa tgtgtatttc acacaaatta
    35341 atcaacttcc ccttccgagg atctggcctg aaaggtcgga taagatatgt taaacagtat
    35401 tttagtcata ctctgcttga tcgctgtaag tgcgttcttc tcgatgtctg agatctcact
    35461 tgccgcctca cgcaaaatca aacttaaact gctggctgat gaaggcaata taaatgccca
    35521 acgcgttctg aatatgcagg aaaatcccgg catgttcttt acggtggtcc aaatcggtct
    35581 gaacgcagtt gcgattctcg gcggtatcgt cggtgatgcg gcattttctc cagcttttca
    35641 cagcctgttc tcccgctata tgtcggcaga actctctgag caactgagct ttattctctc
    35701 tttctcgtta gtgactggca tgtttatcct gtttgcggat ttaaccccga aacgcatcgg
    35761 tatgattgcg ccagaagcgg tggctttgcg tatcatcaac ccgatgcgct tctgcctgta
    35821 cgtttgcacc ccgctggtgt ggttcttcaa cggcctggcg aacatgatct tccgtatttt
    35881 caaactgcca atggtacgta aagatgacat cacttctgat gacatctacg cggtagtgga
    35941 agccggtgcg ctggcgggcg tgttacgtaa acaggaacac gagctgattg aaaacgtctt
    36001 tgagctggaa tcccgtaccg ttccgtcttc aatgacaccg cgtgaaaacg tgatttggtt
    36061 tgatctccac gaagatgagc aaagcctgaa gaataaggtg gcggaacatc cgcactctaa
    36121 gttcctcgtc tgtaatgaag atattgacca catcatcggt tatgtcgatt ctaaagacct
    36181 gctgaaccgc gtgctggcta accaaagcct ggcactgaac agcggcgtac aaattcgcaa
    36241 cacgctgatt gtgccggata cgttaaccct ttcagaggcg ttggaaagtt ttaaaaccgc
    36301 aggtgaagac ttcgcggtga tcatgaacga gtacgcgctg gtggtgggga tcatcaccct
    36361 caacgacgtg atgaccacgc tgatgggcga tctggtcggt caggggctgg aagagcagat
    36421 tgtcgcccgt gatgagaact catggctgat tgacggcggc accccaattg acgacgtcat
    36481 gcgcgtgctg gatattgacg agttcccgca gtcgggcaac tacgaaacca tcggaggctt
    36541 tatgatgttt atgctgcgta agatcccgaa acgcaccgat tcggtgaaat tcgccggcta
    36601 caaatttgaa gtggtggata tcgataacta ccgcatcgac cagttgctgg tgacccggat
    36661 cgacagcaag gccaccgccc tttcgccaaa actgcctgac gctaaagata aagaagaaag
    36721 cgtcgcgtaa cccccagaaa catcaacggc tcctgaatca ggagccgtct tattactgca
    36781 tagcactttg gttaagccat ctctgtttgc agacgcataa cctgacggtt aacttcggac
    36841 atcactgaca aatgcagctt atccttcact tttgggataa gaatcttacc cttatcaaat
    36901 tcaaaagcgc caacgtcctt gatgtataac cgtccacgga acaggatctt tacgtacttc
    36961 gccacctgaa gtgggttgta ccgttggaaa attttcattg ttatctcctg ctgagtatta
    37021 cgcctgtgcg gtgccacaat cggcccaact attatgaggc gcaaatttta atgcctagtg
    37081 actatagact atccgggcaa tgtttccacc gcgtataact ttttttacct aaaggttaca
    37141 attattcaga attatctttt taccgaagcg cggtcttcag tataagcatt catttttcat
    37201 atgatttgtg cgcttgaccg caaactggca tcacacttgc gggaaattcg ataaatagca
    37261 catatgatta aaactcagac ccaagtggtc gtatcacctg catatcataa gaaggaaaca
    37321 ccatgaccct acgcaagatt ctggcactca cctgcctgct gttgccgatg atggcttccg
    37381 cacatcagtt cgaaaccggt cagcgagtgc cgccgattgg catcaccgat cgtggcgagt
    37441 tggtgcttga taaagatcag tttagctaca aaacctggaa cagcgcgcag ttagtgggaa
    37501 aagtgcgagt actgcaacat attgctggtc gcacctctgc aaaagagaaa aacgcgacgc
    37561 tgattgaagc gattaaatca gcgaagttac cgcacgatcg ttaccagacc accaccattg
    37621 ttaacaccga cgacgcaatt ccgggttccg gcatgtttgt gcgcagcagt ctggagagta
    37681 ataaaaagct ttatccctgg tcgcagttta ttgttgatag caatggcgtc gcacgcggtg
    37741 cctggcagct ggatgaaaaa agttccgctg tagtggtgct ggataaagac ggtcgcgtgc
    37801 aatgggccaa agacggggcg cttactcagg aagaggtgca gcaagtgatg gacctgctgc
    37861 ataaattaat taataaatag acactctgaa cccaggattc aggaacgact cgcgcggagt
    37921 gtaatccagc ggtttaccct gccagtcgtg aacgtgcgct ccggcagctg cggccacagc
    37981 atgtccagcg gcggtgtccc aaatattcgt tggtccgaag cgcgggtaca gctgcgcctg
    38041 tccttccgcc accaggcaga atttcagcga agagccgatg gacgtggtct gatgttcgcc
    38101 aagctgttgc agatactctt tcagctccgc atctgcatgg gaacggctga taaccaccag
    38161 cggcgggcgc gcatcgcgga cctgaatctg cttgcgcaca ccgcactctt ctttccaggc
    38221 cttgccttct gccgcgctgt acattacgtt cattaccggc gcatacacca cacctaaaat
    38281 cggtttgcca tggtcaatga gcgcaatgtt aacggtgaat tcgccattgc gtttaataaa
    38341 ctctttagta ccatccagcg ggtctaccag ccagtaacgc tgccagtgct gacggacttc
    38401 ccaaccggga ggatcttctt cagaaaggac cggaatatcc ggtgtcagcg tacgtaaacc
    38461 gtccatgata acggtgtgtg cggcaatatc cgctgccgtt accggagaat tgtccgcttt
    38521 gctgacgacg tccatcggtt tcgtcccgtc gtagacctgc ataatggcat cgcctgcatt
    38581 ccgtgcaagc tggcatactt gatctaacat ttctccacct cgtctctgtg agcggtgtta
    38641 acttattgtt ttacttatac cctatcgtta atgaatgcgc caactgtgat agtgtcatca
    38701 ttttcaaagc gtaaaattgt ggcattcttc actgttctat aagtaagacg tttattctcc
    38761 cttttctttc gtattcccga tgataaaagg atgtccctga tgattaagtt tagcgcaacg
    38821 ctcctggcca cgctgattgc cgccagtgtg aatgcagcga cggtcgatct gcgtatcatg
    38881 gaaaccactg atctgcatag caacatgatg gatttcgatt attacaaaga caccgccacg
    38941 gaaaaattcg gactggtacg tacggcaagc ctgattaacg atgcccgcaa tgaagtgaaa
    39001 aacagcgtac tggtcgataa cggcgatttg attcagggga gtccgctggc cgattacatg
    39061 tcggcgaaag gattaaaagc aggtgatgtt catccggttt ataaggcgct gaatacgctg
    39121 gattatacgg tcggtacact cggcaatcat gaatttaact acggcctgga ttacctgaaa
    39181 aatgcgctgg cgggagcgaa attcccttat gtaaatgcca acgtcattga cgccagaacc
    39241 aaacagccaa tgtttacacc gtatttaatt aaagataccg aagtggtcga taaagacgga
    39301 aaaaaacaga cgctgaagat tggctatatt ggcgtcgtgc cgccgcaaat catgggctgg
    39361 gataaagcta atttatccgg aaaagtgacg gtgaatgata ttaccgaaac cgtgcgcaaa
    39421 tacgtgcctg aaatgcgcga gaaaggtgcc gatgtcgttg tcgttctggc gcattccggg
    39481 ctgtctgccg atccgtataa agtaatggcg gaaaactcag tttattacct cagtgaaatt
    39541 ccgggcgtta acgccattat gtttggccat gctcacgccg ttttcccggg taaagatttt
    39601 gctgatatcg aaggggctga tatcaccaaa ggcacgctga atggtgttcc ggcggtaatg
    39661 ccgggcatgt ggggcgatca tcttggtgtg gtcgacttac aactcagtaa tgacagcggt
    39721 aaatggcagg tgacgcaggc gaaagcggaa gcacgaccga tttacgacat cgctaataaa
    39781 aaatccctcg cggcggaaga cagcaagctg gtagaaacac tcaaagccga tcacgatgcc
    39841 acacgccagt tcgtcagcaa gccaatcggt aaatctgccg acaatatgta tagctatctg
    39901 gcactggtgc aggacgatcc gaccgtgcag gtggtgaaca acgcgcaaaa agcgtatgtc
    39961 gaacattaca ttcagggcga tccggatctg gcaaaactgc cggtgctttc agctgccgca
    40021 ccgtttaaag ttggtggtcg caaaaatgac ccggcaagct atgtggaggt ggaaaaaggc
    40081 cagttgacct tccgtaatgc cgccgatctt tatctctacc ccaatacact gattgtggtg
    40141 aaagccagcg gtaaagaggt gaaagagtgg ctggagtgct ctgccggaca gtttaaccag
    40201 attgatccta acagcacgaa accacagtca ctcattaact gggatggttt ccgcacttat
    40261 aactttgatg tgattgatgg tgtgaattat cagattgatg ttacccagcc cgcccgttat
    40321 gacggcgagt gccagatgat taatgccaat gcggaaagga ttaagaacct gacctttaac
    40381 ggcaagccga ttgatccgaa cgccatgttc ctcgttgcca ccaataacta tcgcgcttac
    40441 ggcggcaaat ttgccggtac gggcgacagc catatcgctt ttgcttcacc ggatgagaac
    40501 cgctcggtgc tggcagcgtg gattgctgat gagtcgaaac gtgcggggga aattcacccg
    40561 gcggcagata acaactggcg tttagcaccg attgctggcg ataagaaact ggatatccgt
    40621 ttcgaaactt ccccgtcaga taaagccgca gcgtttatta aagagaaagg gcaatatccg
    40681 atgaataaag tcgcgaccga tgatatcggg tttgcgattt atcaggtgga tttgagtaag
    40741 taaaacactt ctttttcggc ctataaatca tcaaccgcat ccggcattta ttggcggatg
    40801 cgatgctggc gcatattatc cgccctacaa gccatgcacc gtagaccaga taagctcagc
    40861 gcatccggca gttatgccgc acgttcatcc cgcaccgcca acacctcggg caaattcaac
    40921 tcaatccagt ccgccagtgc agcaaccttt tcgctcacct gctcgcccag cggcgtgagg
    40981 ctgtattcaa catgcggtgg caccaccgga tacgcgatac ggttaagaaa accatcctgt
    41041 tctaacgcct gtaacgactg cgcaagcatc ttttcgctca ccccgccgat tttgcgccgc
    41101 aggtcgctaa agcgatgagt accttcgcgt agcgccacca gaatcaacac cccccaacgg
    41161 ctggtgacgt gtttcaacac ctcgcgcgac gggcactgtt ccgcaaagag attaccctct
    41221 ttcagttgtt gcgacaggct aacctgactc atttcatact tacctttttg tacgtactta
    41281 ctaaaagtaa gtttaggtgt tagcgtattt aaactcaaga caaaacgatg gagacttccc
    41341 atgatcgcta ttactggtgc cactggccaa cttggtcact atgttattga atccttgatg
    41401 aaaacggttc ctgccagcca aatagtggct atcgttcgta atccggcaaa agcccaggcc
    41461 ctggcagcac aaggcattac cgtgcgtcag gctgactacg gcgatgaagc cgcactgaca
    41521 tctgcacttc agggagtgga aaaactactg ctgatctctt ccagcgaagt gggccagcgt
    41581 gccccgcagc atcgcaatgt gattaacgcg gcgaaggcgg cgggcgtgaa atttatcgct
    41641 tataccagtc tgcttcacgc ggataaatct ccgctcggcc tcgccgatga gcacatcgag
    41701 acggagaaaa tgctggctga ttctggcatc gtttacaccc tgctgcgcaa cggctggtac
    41761 agcgaaaact acctcgccag cgcaccggca gcactggagc acggcgtatt tatcggtgcc
    41821 gcgggcgatg gcaaaattgc ctcagcaacg cgggcagatt atgcggcagc tgcggcacgc
    41881 gtgattagcg aagccggtca cgaaggcaag gtttacgaac tggcgggcga tagtgcctgg
    41941 acgttgacac agttagcggc agagctgacc aaacagagcg gcaaacaggt tacctatcaa
    42001 aatctgagcg aagccgattt cgcgcggcac tgaaaagtgt cggactgccc gacggactgg
    42061 cggatatgct ggcggattct gacgttggcg catcgaaagg cggtctgttt gatgacagca
    42121 aaacgcttag caaattgatt ggccgcccaa cgacaacgtt agccgaaagc gtaagccatc
    42181 tttttaatgt taataactag ttaattaaag tggcatcctc ccgcatcctc tctgataatg
    42241 acgggatgcc gggagcaatc atgtctgctt cctgaacgtt tcttctgaca gaccaatgga
    42301 tgccagtaat gattagcggc gtgctgtacg ccctgttagc agggttgatg tgggggctta
    42361 tttttgtcgg gccgttgatc gtgccggaat acccggcgat gttgcagtcg atggggcgtt
    42421 atctggcgtt agggttaatt gcgctaccca ttgcctggct gggacgcgtg cgtctgcgtc
    42481 agttggcgcg tcgcgactgg cttaccgcct tgatgctcac tatgatgggc aacctcattt
    42541 attacttctg ccttgccagt gccattcaac gtactggcgc gcctgtttcc acgatgatta
    42601 tcggcaccct gccggtggtc attcctgtct ttgccaatct gctttatagc cagcgcgacg
    42661 gcaaactcgc gtggggaaaa ctcgccccgg cactgatttg tattggcatc ggcctcgcga
    42721 gtgtgaatat tgctgagtta aaccacggac tccccgattt tgactgggca cgttatacct
    42781 ctggcatcgt gctagcgtta gtttccgtgg tctgctgggc gtggtatgcc ctgcgcaacg
    42841 cccgctggct gcgggaaaat cccgacaaac atccgatgat gtgggcaaca gcgcaggcgc
    42901 tggtcacact gccggtttca cttatcggct atctcgtcgc ttgttactgg ctgaatacgc
    42961 aaacgccgga cttctcccta ccctttggcc cccgtccgct ggtgtttatt agtctgatga
    43021 ttgcgatagc cgtgctttgc tcatgggttg gcgcactctg ctggaacgtc gccagccagc
    43081 gattaccgac agtgattctc gggccgctga ttgttttcga aacgctggca ggtttgctgt
    43141 acaccttttt actccgccag caaatgccgc cgctaatgac gctgagcggt atcgcgctgt
    43201 tagtgattgg cgtggtcatc gcggtcagag caaaaccaga aaaaccttta actgaatctg
    43261 tctcagaaag ttgacacgct ggcagtgagt taaataagcc tctgctacgt aagggttata
    43321 gcttttgcct taaagatgca tttaaaatac atcttatctt attaagaatg aggtatcagc
    43381 tatggcttat cgcgaccaac ctttaggtga actggcgctc tctattcctc gcgcttcagc
    43441 tctgtttcgt aaatatgata tggattactg ctgtggcggt aagcagacgc tggcgcgcgc
    43501 ggcggcacgt aaagaactgg atgttgaggt cattgaagct gaactggcaa agctcgctga
    43561 acaaccgatt gagaaagact ggcgtagcgc cccgctggca gaaatcattg accatatcat
    43621 cgtgcgctac cacgatcgtc accgcgagca gttgccggag ctgatcctgc aagcgactaa
    43681 agtcgagcgc gttcacgccg acaaaccgag cgtgccaaaa gggctgacaa aatacctgac
    43741 tatgctgcat gaagagcttt ccagccacat gatgaaagaa gagcagatcc tcttcccgat
    43801 gatcaaacaa ggcatgggca gccaggcaat ggggccaatc agcgtaatgg aaagcgagca
    43861 cgatgaagcg ggtgaactgc tggaagtaat caaacacact accaataacg tcacaccgcc
    43921 gccggaagcc tgcaccacct ggaaagcgat gtataacggc attaatgaac tgattgatga
    43981 cctgatggat cacatcagcc tggaaaacaa tgtactgttc ccacgcgcgc tggcgggtga
    44041 gtgatctaaa agctggatgg cattgcgcca tccagcatga taatgcggtt atttccgcag
    44101 ttcagcagcc cgcttcttac caataaacag ccagcccaac cccagcgcga taaaccacag
    44161 cggagtaacc agcagcgcct ggcgagtgtc atcttccagt gtcagcaaca cgaccacgaa
    44221 cacaaagaac gccatacata cccagcacat cagcttgccg agcggcatct tgtagatcga
    44281 cttctcatgc agatgaggac gctgtttgcg gtacaccagg tacgagcaaa ggataattgt
    44341 ccagacgaac ataaacagaa tcgcggaaac ggttgtaatc atcgtgaacg cgccaatcac
    44401 gctaggattc acatacaaca tcaccacgcc gccgagcaga cagatacacg agaaggtcaa
    44461 ccctttcgcg ggtactgcgc gcttagaaag tttagcgaac gctttcggcg caacaccttc
    44521 ctgcgccaga ccaaacagca tacggctggt agagaagaca ccgctgttag cggaagacgc
    44581 cgcagaggtc agcaccacaa agttgatcac gctggcagcc gcaggcaaac ctaccaacac
    44641 aaacagctca acgaacgggc ttttctccgg gactaccgaa ctccacggcg tcacggacat
    44701 aatcacaatc agcgcgaaga cgtagaacat aatgatacgg atcggaatgg agttaatcgc
    44761 gcgtggcagt gatttctccg gatctttggt ttccgcagct gtagtaccta ccagctcaat
    44821 ccccacgaaa gcgaaaaccg ctatctggaa tccggcaaag aagccactta aacctttcgg
    44881 gaaccagccg ccgtcattcc acaaatgcgc gaatgacgct tccacaccgg tcggtgactg
    44941 aaagtgcatc gccaccatga ccaggccgac gacaatcagc gacacgatgg cgacgatttt
    45001 gatcatcgca aaccagaact ccatctcacc gaacattttc acggtggcaa ggttgagcgt
    45061 cagcagcagc actatcaccg ccagcgaggc gacccagtcg gagagatcgg ggaaccagaa
    45121 ctgagcataa gccgtgatcg ccaccacgtc tgccataccg gttacaaccc agcagaacca
    45181 gtaggtccag ccggtgaaat atcctgccca cggcccgagt aaatcggaag cgaagtcact
    45241 aaaagatttg tattccagat tcgaaagcag caattccccc attgcccgca tcacgaaaaa
    45301 gagcataaaa ccaatgatca tataaacgaa aatgatcgac ggcccggcaa ggctaatcgt
    45361 tttgccggac cccataaaca accccgtacc aatggcaccg ccaatggcaa taagctgaat
    45421 atgtcggttt gtgagattgc gccgtagcga ctgttcagcc ggagcctgat catcggcaac
    45481 gacttttacc tgatctacca tgtttttttc ttcctgtacc tgtctgtgtt gttcaggctc
    45541 tacggccttt agtcagtcta tgatacgacg aatctgtatc gggactcatc gatattaggt
    45601 aacaatacgc gggatgaata ctaagattta gatctaatgt taattttatg tttaaagtga
    45661 gtgtcatatc acggtgataa cgcgaaacag ctcacaaaaa tacacgctta cggggtcttt
    45721 gcaacacaaa atagcgccgt ttggcaaact gaagggttta ttgctgaatg cctgctcccc
    45781 tctggttcga ggggaacaga atgcgctgct tagagaattt ccagcagttc gacttcaaac
    45841 accagggtac tgaacggagg gatggatgcg cctgcgccgc gctcgccata tgccagttcc
    45901 tgcgggatag tcagttccca tttagaacct accggcatca gagtcagtgc ttcaatccag
    45961 ccagggatca cgccattaac cggaaattca gcgggttcac cacgagcaac ggagctgtca
    46021 aacacggtgc cgtcgatcag tttaccggtg taatgaacac gaacgcggtc ggtacgtgcc
    46081 ggaattgcgc cttcaccctg gttgatcacg cggaattgca ggccagattc ggtgctattc
    46141 acaccttctt ttttggcgtt ttcttccagg tatttcacac cttcagcagc catcgcctgg
    46201 aaacgctgac gacgaacggc atcggcgcgc tcgtggattt cacgcagcgc gcgatgcacc
    46261 acatcaaccg gaacagccgg atgtttgcct tccagcgcat cggcaatacc tgcaaccagt
    46321 gcttctggca gcagcccttc caggccagat tcactcagtt gttgccctac ctgcaaacca
    46381 atgccgtagc ttgcttgcgc ttcgatggtg tcaaaagttg gggtggtcat cgtatttcct
    46441 ttcttagggt ataaaagtag cgggcagcat atcagccaca cttctttggg taaaactttg
    46501 tcgcaggaat gatgacaaat cccggggaaa aagaaacaat agcaatatcc cgtatgaata
    46561 taataaaggc gggtttacca cggacatcat agcgttagct tattcatagg ctatgattga
    46621 ggaacaagac gcggagcagg aggaaaccat gcccgggcgc tttgaactaa aaccaaccct
    46681 ggagaaagtc tggcacgcgc cggacaattt tcgcttcatg gacccgctgc cgccgatgca
    46741 tcgtcggggg atcattattg ccgccattgt attggtggtc ggatttctgc ttccatctga
    46801 tgatacgccc aacgcgccgg tggtgacgcg tgaagcgcag ttagatattc agtcgcaatc
    46861 acaaccgccg acagaagaac agctgcgggc acaattagtc acaccacaaa atgatcctga
    46921 tcaggtggct ccggtcgctc cagaacctat acaggaaggc cagccagaag agcagccgca
    46981 aactacccaa acgcaaccat tccagccaga tagcggaatt gataatcaat ggcgctctta
    47041 ccgtgtcgaa cccggtaaaa cgatggcgca gctgttccgc gaccacggac tgcccgctac
    47101 cgatgtctat gcaatggcgc aggtagaagg cgcgggtaag ccgctgagta atttgcaaaa
    47161 cgggcaaatg gtgaaaatcc gccagaacgc cagcggcgtg gtgacgggct taaccattga
    47221 tacggggaat aatcaacagg tcctgtttac ccgccagccg gatggcagtt ttattcgtgc
    47281 gcggtagatg aagggtcaac caaaagccag ctaaggattg tctctttgat gaccttacgt
    47341 ctggcttcca gtgcctgggg ggaaaccata ctgatatgat aaaccaggcc aagcgtatgc
    47401 tggttgatca aataatatcc gccaagcgca gcaatattaa tattcacctg caatgggtcg
    47461 atatctggct taaaaatatt gtgtttcttc ccttcatcca ataaggattc cattaactgc
    47521 aagtgcgcat ggttaatttc taagagacgc tgtgattttg cataatgcac acctttactt
    47581 tgattttcac tatgcacaat ttttaaaaac caggggttag caatataata atcccatgta
    47641 aaatcaataa ttttctcaat ggctttttgt ggcggaagat ctgagaaatc aagggccttt
    47701 tctttttgtc gaatatcgtt ccaggtatat tccagtactt caataaataa attttcttta
    47761 ttaccaaagt gatgataaac cgtctgttta ctacaccccg cagccttaac aatattatcg
    47821 accctggccc cttcataacc atattcggca aattcattaa ccgcgcataa cagcagcttt
    47881 tccttcaggc tctgtacgtt gctggtatca agatacataa cgcttcccca cgacctcttc
    47941 aagataacta tcttaacccg attaattaga agctccagta aaaaggataa aaacttgtac
    48001 tttcatcaag ttatcaaatg tcctgtgatc actatcgcat atcaaccaac cagatggttg
    48061 atctttcttg cggcacgtcg caagctaatt gtcacttaga aaacaatatt caaaaaaaga
    48121 gagctattgt atgaaatcca ctcgtcctgt tgccgtgatt accggagccg ctcgtggtat
    48181 tggaaagggc tgtgcgctgg agcttgctcg tggcggattt aacctgctga ttaacgatct
    48241 tcccgatgcc gacagcgtag aaaaactgca tatcacacaa caagaatgta tagctgaagg
    48301 cgtggaagtg atttgcttcc ctgccgatgt cggcgatctc tccttgcatg aagagatgct
    48361 cgacgcggca caaaaccagt ggggacgtct ggactgcctg ctcaacaacg caggcatttc
    48421 agtgaaaaaa cgcggtgacc ttctcgacct cgaaccagac agcttcgacc aaaatattgc
    48481 cattaacacc cgcgcgccgt tcttcctcgc tcaggcattc agtaaacgtc tgctcgcaca
    48541 gccgaaaccg gaagcagaac tgccgcaccg ctcgattatt ttcgtcagtt ccatcaacgc
    48601 catcatgctg gcgatgaatc gcggcgaata taccattgcc aaaaccgccg tttctgccgc
    48661 tgctcgtctg tttgctgctc gcctttgtaa tgaacaaatt ggcgtttatg aagtgcgccc
    48721 cggtctcatc aaaaccgata tgactattcc ggcaacggct tattacgacg aactgattgc
    48781 caaaggtctg gtgccgtggg gacgttgggg ttatccggct gatattgctt ccactgtccg
    48841 cgcgatggcg gaaggtaaac tgatttacac ctgtggtcag gcggtcgcca tcgacggcgg
    48901 cttaagtatg ccgcgcttct gaggctgaat catgagagat ctgttacaac gcccggattt
    48961 attcagtatc aataccgcaa cactgggcta taaaacgccg ctacccgcca ttattgatgc
    49021 ctgcgccgcg cgtggtattg gcgcgattgc tccctggcgc agggagttgc aaggtgaaga
    49081 tctccagcaa atcgcccacc agcttgccgc cagtaacatg agcgtttccg gtttgtgccg
    49141 tagcacttac tacaccgcgc cgacactggc ggaacgcaaa ctggcgattg atgataaccg
    49201 ccgggcgctg gacgacgcag cggtgcttaa cgccgcctgt tatatgcagg tggttggcgg
    49261 tctgccaacg ggcacaaaag atctgtacga agcgcgggaa caagtaaaac aagggattcg
    49321 ccagttgctg ccacattcga aagatgtcgg cgtgccaatt gcgctggagc cactgcaccc
    49381 gatgacagct gccgatcgct cttgcctgtg cacgttacgc caggcgctgg actggtgtga
    49441 tgaactcgat cccgatggtg agtttggcct cggcgtggcg gtggatgttt atcacgtctg
    49501 gtgggatccg gatctcgcca gtcagatcct gcgtgccgga aaacgcatcc tcgcgtttca
    49561 tgtttccgac tggttagtgc cgaccactga tctggtcaat gaccgtggta tgccgggaga
    49621 tggcgtcatc aatattccgt caattcgtcg gctggttgaa aacgccggat ttaatggtgc
    49681 tattgaactg gaaatattct cgccttactg gtggcagaaa gatattaaca gcacgctgga
    49741 tattagcgtc gatcgcatcg cgcattattg ttaaggaatg atcatgagtg accaacccgt
    49801 tctgttcagc agagtggcgg cttcctgccg cctgacattg aaccgtgaag ataaatgtca
    49861 tgctattaac gaagagatga tcgaatctct cgaccattat ttaaatgaaa ttgaaaacga
    49921 caccacatta cgattagtcg aattaacggc aaccggcgat aaattctttt gtgcgggcgg
    49981 cgatattaaa tcgtggtcgg cctattcgcc attagatatg ggcagaaaat ggattaaacg
    50041 cggtaatgac gtttttaatc gcctgcgaaa cttaccccaa ttaaccgttg cgaatctcaa
    50101 cggtcatacc atcggcggtg gtattgaact ggccttgtgc tgcgatattc gtattgcccg
    50161 ccccggcgcg aaattctcta acccggaagt gatgctcggc atggtgcctg gctggatggg
    50221 cattgaacgt gtgcttaatc aggttggtcc ggtggtcggt cgccagatgc tgatgctggg
    50281 taaacgcctg acggcgcagg aagcccaggc ggcgaattta attgatgaag tggtagaaaa
    50341 agaacaggtg gaaagctgga tggcgaacca gttagcgcag ctggaaaaat gcggtccggt
    50401 ggcgcttgca catattaagc aactgattct ggcactggaa aataaacatg ccgattaccc
    50461 gcaccagcta ctggccggat taatgtccgc cactcaggat tgccagcagg cgacgcgcgc
    50521 ctttgccgaa aaaagtagcg taagcttcca taatcaataa ggaaattgta tgcgtaagat
    50581 aacaaccgcc gaggcactgg cggcgcaaat tcaggacggt gcgactattg ctattagcgg
    50641 taacggcggc ggtatggtgg aagcggacca tattctggct gctattgaag cgcgtttcct
    50701 gcaaaccgga caccctcgcg acctgacgct aatccactcg ctgggtattg gcgatcgcga
    50761 ctgcaaaggc actaatcgtt ttgcgcacgc agagatgctc aaacgcatta ttgccgggca
    50821 ctttacctgg tcgcccaaaa tgcaggcgct ggtaaaaaat aacacgattg aagcctactg
    50881 ctttcctggt ggcgtgattc aggcactgct acgggagatc ggcgccggac gtccggggct
    50941 ttttacccac gttgggctgg gatcgtttgt tgatccacgc aatggcggcg gtaagtcgaa
    51001 tgaatgcact accgacgacc tggtagaact gattgaaatc gatggtgaaa ccaaacttcg
    51061 ttatcgccct ttcaaagtgg attacgcgat tttgcgtggc acttatgccg atcctcgagg
    51121 caacgtcagc cttgaagaag aagcgattga tatggatagc tattccatgg cgctggcagc
    51181 acacaacagc ggcggcaaag tgttcgtaca ggtacgcgat gtgctggaag ctggcgcgat
    51241 tgaaccacgc cgggtcaaat taccgggcat tctggttgat ggcatcgttg aacaccgcga
    51301 acaaccgcaa acctatcttg gcggttacga cctgaccatt agcggtcaac atcgccgtct
    51361 gagttctaac gacgctattg aactggttag tcatccggtg cgccgcctga ttgcccgtcg
    51421 ggcagcacgc gaactggtgg ctggcgcttc aaccaacttt ggctttggta ttcctggcgg
    51481 tattccaggc gtagcgctgc gcgaaggcgt tccttaccaa agtttatggc tgagcgtcga
    51541 gcaaggcgta cataacggca tgatgcttga tgatgcgttt ttcggctgcg cccgcaacgc
    51601 cgatgccatt attccatcac tcgatcaatt tgagttctac agtggcggag ggatcgatat
    51661 caccttcctc ggcatgggag agatggatca gtacggtaac gtcaacgtct cccatctcaa
    51721 tggcaatctc attggtcccg gcggttttct cgaaattgcg caaaacgccc gtaaagtggt
    51781 gttctgcggc acgttcgacg ccaaaggtag caagattgat gtaacgccag atggcttgca
    51841 tatcacccag tcaggtcaaa tccctaaact ggttacccag gtggaaaaaa tcacttttag
    51901 cgccgcctac gcacagcaaa gtggtcagga agtgttgtat atcactgaac gcgcagtatt
    51961 ccagttaacg gcagaaggcg ttgaattaat tgaaatcgcg ccgggtgtgg agattgagcg
    52021 cgacattctg ccgtatatgg ctttccgtcc aattatcaag cacccacgcc tgatggaaag
    52081 tagcctgttt acgccgatgg aggatgcatg agtcagcttg atgacaccat ccttgatgcg
    52141 ctgacgcacg ttactttccc aaagggtttt gcacaggcag agcccgcatg ggttgtcacg
    52201 gtagacggtg ttgattaccc actctggcaa acagatgccc tggtagtcgg cagtggtgca
    52261 gcaggattac gtgcggcagt tgaacttaaa cgccgccagc aaaatgtgct gatcgctacc
    52321 gccgggttat atatggggac gtcggcatgt tctggttccg ataaacagac actatttacc
    52381 gccgctaccg cgggcaacgg cgacaacttc accaaactgg cagaggcact ggcgagcggt
    52441 ggggcgatgg atcacgacac cgcttatgtc gaagcggtag gttctctgca cactctaggc
    52501 gggttgcaat atcttggtct ggaattaccg gaagatcgct atggcgcgat tcttcgttat
    52561 caaaccgacc atgacgaagc cgggcgtgca acctcgtgtg ggccgcgtac ctcaaggtta
    52621 atggtgaaag tgctgttgga agaagtacag cgcctcgcca ttccagtgtt gaccagtgca
    52681 acagtgatta aactgctgca tcagcgtgac gaaaacggcg aagaccgcgt ggcaggggca
    52741 atcctcgcga ccggtcatcg cgcccataac ccatgggggc tggcaattgt gactgcgccc
    52801 aatgtggtac tggcaacggg cggaccgggc gagctttatc gcgacagtgt ttatccacat
    52861 aaatgcttcg gctcgctggg gctggcgctg gaggaaggtc tgacgctaac caatctgacc
    52921 gaaagccagt ttggtatagg cacgccgcgt agcacgtttc cgtggaattt atccggcacc
    52981 tatgtgcagg tgatcccgta tatctattcc gtggatgctg agggtaacga gtataacttc
    53041 ctcgcggatt actatcgcac cacccaggag ctggcttcaa acattttccg taaaggctat
    53101 cagtggccgt tccacgccac tcgggtgatg gattttggct ccagcttgtt agatatggca
    53161 gtagcgcaag agcagcaatc agggtgtcag gtatttatgg atttcaatcg caatcctgaa
    53221 gcggtgccgg gtgacctgcc gttctcatta gatcgactgg acgacgacgt tcgcgcgtat
    53281 ctggaaaata acgacgctct ggcaccatcg cccatcgaac ggctgcaacg aatgaatccg
    53341 ctgtctatct cgctgtataa gatgcacggt tacgatctca ccacacagcc tttgcagttt
    53401 gccatgaata atcagcatat gaatggcggc attgaagtgg atatctgggg acaaacctcc
    53461 ctgcccggct gtttcgccgt gggggaagtt gctggcacac acggcgtcac tcgccctggt
    53521 ggtgcagcat tgaatgccgg gcaggttttt gctgttcgtc tggcacgttt tattggttgc
    53581 acgcaaaagc ggaatattga tggagatata gcacagctgg tagctcctac actggcttct
    53641 ataagagaga tcattactca ggcgcacgat aacgggaccg ggatgccgtt gtcggttgtg
    53701 agagaaaaaa ttcaggcacg aatgtctgac catgcgggat ttatttgcca tgccgataaa
    53761 gtccgacgcg ccactcgcga tgccctgcta ttgagcgaat ttgtccaacg gcatggattg
    53821 gctatcaaac atgtgggtga agttgccgag ctgtttatgt ggcggcatat ggcactgact
    53881 tctgccgccg tattaacgca attaacgcat tatattgacg caggtggtgg tagtcgggga
    53941 gcacgtatta ttctcgacag ggatggaaat tctattccgc aaacacgaaa tggtttttgt
    54001 gatgcctggc gctttcgttc agagcgtact gaggataaaa aagataaact acttattcat
    54061 tattgcaacg gtatctttca cgtcagagaa acacctgttc gtgagtttcc tattatccga
    54121 ggtatttggt ttgaaaaaaa ctggcctggt tttcttaatg ggacaattta ccagccacag
    54181 gatgaatgat attgcaaagg ttaatcacta tgcgaaatat aattagatct attaatgctc
    54241 tacttgcagc attgaacatt accattttgg cgatcatcgt ggcatgtgtg acgtggcagg
    54301 tggctgcacg atttatattt actagtccca gtatttttac agatgaactc agccgtttgc
    54361 tctttatttg tcttggactt tttggtgggg catacaccgc agggcaaaac cggcatctgg
    54421 cgattgacct gctacctatg atgctgaaag gaaaagcccg acgtcattta tttttgtgta
    54481 ttcagattat cgttattatc ttcgcaacca tcattatggt atatggtggt gggctattaa
    54541 cgatggatac attcgattca ggtcagacct cgcccgcttt aggctggcaa atgggatata
    54601 tctatatgag catcccgatt agtggtgtac ttattattat atacaccata gatatggttt
    54661 taaccgaact taaacaacca ctctaaagat aacaaacaac aaccaaccat agtaggaatg
    54721 gagaaattat ggattactgg ttaccgatta ttgtgttatt tggtgccttc ttttttatgt
    54781 tggcattagg tgtacctatt gtttatgcca ttggtttatc gacactggca tcaatttcca
    54841 cacaactcga tttcaactca gcattgagtg tggtttccca aaagttagcc tccgggttag
    54901 atagttttac gttgttggca atcccatttt ttatcttgtc tggcaacatt atgaaccatg
    54961 gaggaatagc gcgacgatta atcaactttg cccgtattct cggcggtcgt ctgccaggct
    55021 cacttgccca ctgtaatatt ctcgccaata tgctgttcgg ggcaatttct ggttcagccg
    55081 tggcttcggc ggctgcgatg ggcggcgtca tgcatccgca acaggttaaa gagggttacg
    55141 acccggcatt cagtactgcg gttaacgttg cctctgcccc gacgggtttg cttattccac
    55201 caagtaatac gttaatcgtc tattcactgg tcagtggtgg tacttctatt gccgcactgt
    55261 tcctggcggg ttatgttccg ggaattttgc tgggtctggc actgatggta atagccggta
    55321 ttatcgcggt acgtcgcggt tatccaaagc cagaacgccc gactttacgc caggctggcg
    55381 ttgcgatatg gatggctatc cccagtattt tcctgattat tttaattatg gggggtgtat
    55441 taagtggtat ttttaccccg acagaggcct ccgcaattgc agtaatttat acccttttcc
    55501 ttgcactggt tctttatcgt gaaatctcag ttaaagattt acctaaaata tttctggaat
    55561 ccgttattac cactgcaatt gtcttgttat taattggttc ttcgatgggt atgtcatggg
    55621 caatgtcaaa cgctgacgtt cccttcctga ttctcgattt gcttaacact atttctgaca
    55681 acccaataat aatcctgctt attatcaata ttatcctgtt gattatcggc acttttatgg
    55741 atatgacacc ggcggtactg atttttacgc cgatattttt accggttgtc accgaactgg
    55801 gcatggaccc gattcacttt ggtattgtca tggtactgaa catgtgtatc ggtatttgta
    55861 ctccgcctgt aggcagtgtg ttatttgtcg gttgtagtgt atctaaatta ccgattaata
    55921 aaattatcaa acctatgctg ccattctatg ccgtgatggt attggtgctg gcaatggtga
    55981 cctatattcc gcaaatcagt atggcattgc caagagcact gggctactga tgcgcattca
    56041 ctggcggcac ctgccgccat atttattaga aaaggaacat ctatgaaaat aaaagtatcc
    56101 gctggcatta tcggtgctgt tcttatgtta tccgcaagcc agtcctgggc agtgacatta
    56161 aaactgagtc ataatcagga taagtctcat cctgttcata aagcgatgga gttctttgcg
    56221 aaaaagagca aagagtactc taacggtgat attactattc gtatttatcc aaatggaaca
    56281 ttgggtactc aacgagaaac aatggagctg attcgttctg gcgctattcc cctggtaaaa
    56341 accaatgcgg cagaaatgga agcatttgaa aattcctata aattatttag cctgccttat
    56401 ttgttccgcg atcgtgatca ttattatcag gtcatgcagg gcgatatcgg gagaaaaatc
    56461 ctcgactcaa cgaaaagcaa aggttatttc gggctgactt tttatgatgg aggcgcccgc
    56521 agtttctatg gcaataaacc agtactgaaa ccagacgatc tgaaaggcat gaaagtccgt
    56581 gtccagccaa gccctggcgc agttgaaatg atcaaagtca tgggcggtaa cccgacgcca
    56641 ctggattacg gcgagttgta tacagcctta cagcagggtg tggtcgatat ggcagaaaac
    56701 agcgtgatgg cgctgaccac catgcgtcac ggtgaagtgg caaaatcctt cagccttgac
    56761 gaacacacta tggttcccga tgtggttctg atgagcaatg ctgcgtttga taaacttagc
    56821 ccggaaaatc aggcagttat attaaaagca gctaaagaat caatgagcta tatgaaagac
    56881 ttgtggagcg aggaagagaa acaagaattt gcgaaactgg ataaaatggg cgtgaaagtc
    56941 taccaggtag ataaagctcc gtttatcgag aaagtacagc caatgtacgc aaacttcgct
    57001 aaggacaacc cagcccttgc cccaatgctg gctgatattc aggcagctaa gtaattatct
    57061 tcgtagggct gcttattgtg gcccttatcg atatctgcaa gtgctcgcta caaaagcaaa
    57121 acgccgacca atggtcggcg tttttacgtc tcgttgaata acgaattatt cagctactac
    57181 gtttacgatc actttcgcga atacttcgct gtgaacctgg aagctcactt cgtgttcgcc
    57241 agtggtacgc agaacgccgt tcggcagacg aacttcgctc ttagccactt caacgccagc
    57301 tgcagttaca gcgtcagcga tgtcgcgagt accgatggaa ccgaacagtt taccttcgtc
    57361 gccagcttta gacgcgatgg taacagtttc cagtgcattg attttctcag cgcgagcatt
    57421 agcagctgcc agaacttcag ccagtttagc ttccagttca gcgcgacgtg cttcgaagaa
    57481 ttcaatgttt ttcttggtag ctggaacagc tttaccctgc ggtaccagga agttacgagc
    57541 atagcccgct ttaacgttta cctgatcacc caggctaccc aggtttgcta ctttatcaag
    57601 cagaataact tgcattacct tatcctctca aagtcgtatt aatggaccgt gaccgattac
    57661 tgatggcgat cagtgtacgg cagcagggac aggtagcgag cgcgtttgat agcgcgagcc
    57721 agctgacgct ggtattttgc acgggtaccg gtgatacggc ttgggacaat cttaccgctt
    57781 tcggtgatgt agtttttcag cgtagcgata tctttatagt cgatctcttg aacgccttcc
    57841 gcggtgaaac ggcagaactt gcgacgacgg aaataacgtg ccatatggct agtctccaga
    57901 atctatcaat tcaatctgct cggcatgcaa aaccattttg ctcagtccgt tctttgcctt
    57961 gtggcatgaa atgaacccct gaacggttat gcgactgccg accgttatac tgtgagtaat
    58021 ggcctggttt tcgtgtccgc taacaataac gggcatttga caccatgcct gccggtgaaa
    58081 gccggcttcc tcctgcacag aacgatgctc aagcacgaac tggcagtgag gaattcctga
    58141 tggactgacc tttcgaaggg gagtcctgca cacggtgccg gacaacacca gacggttggt
    58201 catcagaaat tactcttcag aatccccagc ttcagcatca tcagcggttt cgtttgcgaa
    58261 atcatcgcga cgctcacggc gctcgtcttt cgctttaacc atcggagatg cttcggtaac
    58321 agcgtgcttg gtacgcataa ccatgctgcg gataacggca tcgttgaagc ggaaggtagt
    58381 ttccagctca tcgatcactt cctgcggagc ttcaacgttc atcagaacgt agtgtgcttt
    58441 gtgcagtttg ttgatcgggt aagccagctg acggcggccc cagtcttcca gacggtggat
    58501 cttgccttct gcaccagtga tggcagcagt gtagcgctcg atcatgcccg gaacctgttc
    58561 gctctggtca ggatggacca taaaaacgat ttcgtaatga cgcatcgaat tgctccttac
    58621 ggattattca gcctcctgtc tgggtcagcc gaatcccggg gaggcaagga acgtgttaaa
    58681 ggtcggctga aaaatgacgc gttatagtac ttgtatgccc cgctaaactc aagggcagag
    58741 ccgaaataaa tctccccttt cgcaattaac ctctaaaccg ctgatttgga gttcatcaca
    58801 cttcatcatg gtgttttttt gaacaactgc atcagaaatg gtcaccatca acttctttat
    58861 cattgattaa aattaaatca gaagatcatc acagaggaga gcacacaaag tcagccgtcg
    58921 aggaggtatc tatgttcagt cgagttttag cccttctggc tgtgcttttg ctaagtgcaa
    58981 atacatgggc agccattgaa atcaataacc accaggccag aaatatggac gatatgcaaa
    59041 gcttaggcgt gatttatatc aatcataatt tcgccactga aagtgaagca cgtcaggcat
    59101 taaatgaaga aacagatgcg cagggcgcaa cgtactacca cgtaattctg atgcgggaac
    59161 cggggagtaa cggcaatatg cacgccagcg cggatattta tcgctagcac caggtataac
    59221 caacgaaaca ttgccatagt ttgctttgcc cccttcgcag ggggcttttt ttgaaaaacg
    59281 gctgcggaat tagaccagtt atctcccgaa gaaggaaatt tccgcagcgc gtgttttact
    59341 tctgcccgta ataagcgtta ggaccatgct tacgcatgaa gtgtttattc atcaggaagc
    59401 tgtcgatgtg attgagttgt ggattaatac tgcgcgcaat ccacgccatt ttcgccactt
    59461 cttccatcac taccgcgtta tgcaccgcgt cgtgggcatc tttcccccag gcgaacggtc
    59521 cgtgctgata caccacaatt cccggcgtat gcagcggctc ggcgttgccc agcgtttcga
    59581 taatcacttt gccagtgttc agttcatact caccctgcac ctcttcttcg cttaatccac
    59641 gcgtacacgg gatgtcgcca aagaagtagt cggcatgcgt agtgcctaac gccgggatcg
    59701 ccagccccgc ctgcgcccat gcggtagcat gagtggagtg ggtatggaca atgccgccaa
    59761 gcgacggata acgacggtag agttcaagat gcgtcgcggt gtcggaagac ggacgatatt
    59821 ccccttccac caccttaccg ctcatatcga ccaccaccat atcgtctgct ttcatggttt
    59881 cgtaggcgac gccgctgggc ttgatcacca ccagcccgcg ttcgcggtcg atagcgctga
    59941 cgttgcccca ggtaaaggtc accagcccgt agcgcggcag atccatgttg gcttcaaata
    60001 cctgctgttt tagcttttgc attatgccgc ctccaccatg cccgctttcg ccatgcgcgc
    60061 tttcacccaa tcacgcgctt tcgccacttc tgccgccggg tcttccgccg tttcgctcca
    60121 catctcaatc aggtacggcc cgcaatagcc actctgtttg agcgtttcga aacaacgttc
    60181 gaaatccact acaccttcgc caaacggcac gtttttgaag acgccaggtt tggtgtcttt
    60241 cacatgtacc gcgacgatat gcccgattcc ggcctgcaac tccatctgca catcgttgtc
    60301 ccacgccgac aggttgccga tatccgggta gagctggaac cacgggttgt tgagatagtg
    60361 cgcgtaaccc agcgccttgc tgatggagtt catcaacgga taatccatga tctccatcgc
    60421 cagcgtcacc tgcgcgcggc tcgccatctc aacgctctct ttcaggccgt cacggaaacg
    60481 acgacgcgtt tcgttattgg cttcctgata gtaaacgtca tagcccgcca gctggatcac
    60541 gcgaatgccg acgtcctggg cgaactggat agctttacgc ataatctcca gcccctgcgc
    60601 ccgcaccgcg tcatcttcac tgcccagcgg gaaacgacga tgagcagaaa ggcacatgga
    60661 cggcacgcgc acgccggttt caacaatcgc attcaccagc gccagacgct gctcgcggct
    60721 ccagtcgagg cgcgacaggc gctcgtccgt ttcatctacc gacatctcga caaaatcgaa
    60781 gcccaacgtt tttgccagtt gcaggcgttc cagccagcac tccccggcgg ggagcgcttt
    60841 ttcatagatg ccaagcggga tttgtttgga caacatatcc gctccttagc cccacagttc
    60901 ggcgatggaa cgtttgaact gacgcgcggc ttcaaccgga gaagcggcat cacggatgct
    60961 gcgaccggcg ataaacacat gaattggaat gcctttgaac agcggcagat cttccagcgc
    61021 caggccaccg gtaacggtga ctttgaagcc catatcggaa agacgtttga tcgcagtgat
    61081 atcggcttca ccccacgcca cgccagcggc ctgcgcgtca cggctgcggt gataaaccac
    61141 ctgctgaata cctgcgtcgc gccactgttg cgcctgttcc caggtccagt aaccggtcag
    61201 ttcgatctgc acgtcgccgt taaactcttt tgctacgtcc agcgcacctt tggcggtgtt
    61261 gatatccgca caacaaatca cggtcaccca gtcagcgttg gcttcgaagc acatacgaga
    61321 aagaattttg cccgcatcgg caattttggc gtctgccagc acgattttgt gcgggtagag
    61381 cgctttcaga tcgcgaaccg cacgcacgcc ttcgcccacg cacagaatgg tacccacttc
    61441 gataatgtcg acttcttcgg caatcaggcg agtggtttcg taggcgctat ccatagtctg
    61501 gttgtccagc gcgacttgca acatcggtaa tgacatcttc aattccttct taagctgccg
    61561 cgttggtgcg gtcaatgaga tccagtactt cctgctcggt acggcaggca cgtaaacggt
    61621 cgaaattttc ctcatcttca aacaggttga cgatctgcat gatgcccact tcctggtgcg
    61681 tgttggcatc gaccgccgcc atggtgatga ggatatccac cgggtcgtta tcttcgtggt
    61741 tgaactccag cggctttttc agcgtcacca gcgcaaaacc ggttttctta acaccctctt
    61801 ccgggcgacc gtgcggcatt gccaggccag gtgcgagcac aaagtacgga ccgtgctgtt
    61861 caaccgcatc cagaatcgcc tggtagtaac gcggctcgac aacatccgcc gccaccagca
    61921 ggtcaacgcc gatttttact gcgtcctgcc atgtctcagc ttcagcctgc aggcggatgg
    61981 atttattttc cgccagcgaa tcacgtaatt tcatggcgcg tccttacttc acatcctgcg
    62041 ggaaatgctc tttgatcact tccagcagtt tcgggccaaa atcggcagga gagagcatgt
    62101 tgcgcacgcc aaccacgtat ttgttgccgg tcacggagat ctcgcccgcg atgtgcgtgg
    62161 aagcgatgat aatatccgcg ttgctcagct cacttttgta ctcgccaacc gcgcagctgt
    62221 ttaccgtgtg gtcaatcttt gattgggtta aaaactggtc cactttcatt ttcatgatca
    62281 tggaactacc ttgtccgttg ccacacacag ccagaatacg tacggtcata atcaaaactc
    62341 cttattaagc agactgttct gccagttgtt tttctgcatc ttcttcagcg cgcagtgcgc
    62401 ggccagcgaa gaacatataa gccagtgcaa ttacaatgat gacggccata aaggcgatac
    62461 cgatggagaa gaagccctgc atcatcggcg gtgccagaat cgaccagtcc gccatgccca
    62521 tccaggcgct cataccggtg agtttcaccg cccagacgca gccaaagatt tcaatcatcc
    62581 ccatcaccag acatatcttc agcgccgcac gccagccgcc gaagtggtta gcgaacacgc
    62641 cgatggtggc gttggagaag aacatcggga taaagccggg aataatcagg atcgaggaac
    62701 cgcaggcgac caggatgcca accgcaatca gctgaccgat ggtgccccac ataaagcccc
    62761 aaaccacggc gttcggcgcg aagctataga tagccgcaca gtcaatcgcc agaaccgcac
    62821 cagggatcag gcgctgggag ataccgttaa atgcttcaga gagttccgcc acaaacatgc
    62881 gcacgccctg agtgatgatg aagatcgcca ccgcgaagga gaaaccagtt tgcaggatgt
    62941 acaccgtcca gttcactttg cctgccatcg cctgcacggt gtcgataccg aaggagagca
    63001 gaatggcacc aaagaagatg gtcatcacaa tcgccgtgga gacgatgttg tcgtggaaaa
    63061 tattcagcca gcctggcagt ttgaggtctt caacgctttc ctcttttttg ccgaggaacg
    63121 gcgcaacttt ataggcaatc catgatgcaa actgttgctg gtgaccgatg gagaaaccgc
    63181 agccgtccgt cacttcctga gtcggcttgt acattatgtt ggaggtaatg ccccagtaga
    63241 gcgaaaccag aatcgccgtg cagataatgg tcgtccacat ggagtagccg aaaataaaca
    63301 acgtaacggc aatcagcccc gcctgctgga acatgatatg accagtcagc atgatggtac
    63361 gaataccggt aatgcgacgc agcagcacgt aacagatgtt caacgccagc gctaacaaca
    63421 ccgcgtaacc tacccagtta taggcatcgc ccatgcggtc gatggttgcc atcatcgacg
    63481 cgtaagtatc ggaaattgcg ccgttaatgc cgtagacttc ggacattttc gccaccaccg
    63541 gtttgaaggt gctggtgagg atgccggacc ctgcctgcaa caacatgaaa ccaattatgg
    63601 ttttaatcgt gcctttaata ataacgctga cacttttgcg cagtaggatg tagcccagac
    63661 aggtcacaat acccagcaac aacggggcat tggtcatgac ctggttaaaa aacacggtaa
    63721 agatgttgta gaggatctcc ataacgatct cctgaagaag aggtaaccgg gtattccaca
    63781 cacccggaat gttgtgcact cactctaatt ttcaaaagta atcacaacaa gattatttat
    63841 gattaaatgt gacgcgaccc gcaaataatt ccacatggat agaatgggat tcacacaacg
    63901 aaacaactat tcatttaaat tcatttagtt aattgaatta cacattccat taaatctttc
    63961 cacactcaaa atcaacaacc acttccctgg caaaaagtca aaaaatggtc attgccttcc
    64021 tgaaaaaata gtgtcaggat taatcaaaac caatcacata ttgattcgaa ttgaactatc
    64081 atgaaggtaa atggcgatga gtaaagtgaa aagtatcacc cgagaatcct ggatcctgag
    64141 cactttcccg gagtggggta gctggctgaa tgaagaaatt gaacaagagc aggtcgcctc
    64201 tggcacattt gcgatgtggt ggctaggctg caccgggatc tggttgaaat cagaaggtgg
    64261 caccaacgtt tgcgttgatt tctggtgcgg cactggcaaa caaagtcacg gtaacccgtt
    64321 aatgaaacag ggtcaccaga tgcagcgcat ggctggcgtg aaaaaactgc agccaaacct
    64381 acgcaccacc ccgtttgttc ttgatccgtt tgcgattcgc cagatcgacg cggtactggc
    64441 gactcacgat cacaacgatc atatcgacgt taacgtcgct gctgccgtga tgcagaactg
    64501 tgctgatgac gtaccattca ttggaccgaa aacctgcgtt gatttgtgga ttggctgggg
    64561 cgtaccgaaa gagcgttgca tcgtggtcaa accgggcgat gttgtaaaag tgaaagacat
    64621 tgaaattcat gcgcttgacg ctttcgaccg tactgcactg atcaccctgc ctgccgatca
    64681 aaaagcggct ggcgtactgc cggacggcat ggacgatcgc gcggtgaact atctgttcaa
    64741 aacgcctggc ggctccctgt atcacagcgg cgactcccac tactctaact attatgcgaa
    64801 gcacggtaac gaacatcaga tcgatgtggc gttaggatcg tatggtgaga acccgcgcgg
    64861 tattaccgac aaaatgacca gcgccgatat gctgcgtatg ggtgaagccc tgaatgcgaa
    64921 agtggttatc ccgttccacc acgacatctg gtcaaacttc caggccgatc cgcaagagat
    64981 ccgcgtgctg tgggagatga aaaaagatcg tctgaagtat ggcttcaagc cgtttatctg
    65041 gcaggttggc ggcaaattta cctggccgct ggataaagac aacttcgagt accactatcc
    65101 gcgcggtttc gatgattgct tcactattga accggatctg ccgttcaagt cattcctgta
    65161 atctgtcgtt tataccggat agcgtggaga agttcgcgct atccggcgta gtatttcctg
    65221 gctatttcaa atatcatcta aaaaaatcaa attttatcgg aatagctcat gactgaagca
    65281 caaagacatc aaatcctcct ggaaatgctc gcacaattgg gctttgtgac cgttgagaaa
    65341 gtcgttgagc gtctgggaat ttcgcctgcc actgcgcgac gcgatatcaa taaacttgac
    65401 gaaagcggca aactgaaaaa ggtgcgcaat ggcgcagaag ctattaccca gcagcgcccg
    65461 cgctggacgc cgatgaatct gcatcaggcg cagaatcacg atgaaaaagt acgtatcgct
    65521 aaagcagcct cgcagctggt taatccgggc gaaagcgtag tcatcaactg cggctccacc
    65581 gcgtttctgc ttgggcggga aatgtgtggc aagccagtgc aaatcatcac taattatcta
    65641 ccgctggcaa attacctgat cgatcaagaa catgacagcg tgatcattat gggtggacag
    65701 tacaacaaaa gtcagtccat cactttaagc ccgcagggca gcgaaaacag tctctatgcc
    65761 gggcactgga tgtttaccag cggaaaaggg ctgaccgcag aagggttgta taaaaccgat
    65821 atgctgacag caatggcaga gcagaagatg ctgagcgtgg tagggaaact ggtggtactg
    65881 gttgatagca gtaagattgg cgaacgcgcg ggaatgcttt ttagccgtgc cgatcaaatc
    65941 gatatgctga tcaccggcaa aaatgctaac ccggaaatcc tgcaacaact ggaagcgcaa
    66001 ggggtcagca ttctgcgtgt ttaaagatgc tggcggaaaa atgtcacggc agcatctaac
    66061 gcctcaggcg taatgcggtg acgcacgcct ggctgccatg aacaggttag cagtttatcc
    66121 cgtcccgtct cgcttaaggc ctgctgcaaa cgtagtgatt cgtcggcagg cacaacgtca
    66181 tcgtcgaggc catgccacag cagtagaggt ctgtccccaa gttgttccag gtggtttgtc
    66241 gcttcccact ctgccagcgg cgcgataatg ttattgaatt cattctgctg tgctgccgtt
    66301 tcaggtatca gcggtggaaa cagtgaacgg gcgagcgatg taaaatagcc cgatcccatc
    66361 atgctggcgg tacatttcac cgtggggtgg cgagcggtaa ttcccagtgc cgtcatcgcg
    66421 cccatcgacg cgccaccgac tgccagacgg tcatcaagca gccagttttc ttcggctatt
    66481 gccgcacgta aagtagtgaa ttcctgcata ctttgtagca agatttgcca gaattgattt
    66541 aaccgccgcg cttcgtcgct actaaaacgg ctaccgtgat cgggcgcatc cggcatgatc
    66601 acccgcaaac cagcctgcgc cagcgcaacg gcaaaatagc tatacaccag gctggatgaa
    66661 gtaaagccgt gataaaaaat tacgcacggt aacggggtat ctttttgccc gacaggataa
    66721 gcatgaagaa cgggaatatc tgccagctcg cgtgattcta tttcaatcat ctgtctctcc
    66781 tttttgtctg gtatgacatg aagaaatcct tagcacaagt ttctgctggc ggtattagtt
    66841 cataatgttg agatgtgggt tacgctttcg tcacgttttc attcgaaaat cgcgtaccag
    66901 gtaacaattc gggaacattc ccccaaagtt aaattaataa ggcactacac tatggttagc
    66961 aggaaacgta atagcgttat ttaccggttt gccagtttat tattggtgtt gatgttaagt
    67021 gcctgtagcg cactgcaagg tacgccacag ccagcaccgc cagtaacgaa ccatccgcaa
    67081 gagattcgcc gcgaccagac gcaagggtta cagcgaatag gtagcgtaag cacgatggtt
    67141 cggggttctc cggatgacgc attagcagaa atcagagcaa aagctgtcgc tgcaaaagct
    67201 gattattacg ttgtcgtcat ggtggacgaa accatcgtga caggacagtg gtattcacaa
    67261 gccattttgt accgtaaata aatcagacaa cttacatagt cagctttaca ttgctttgcg
    67321 tccctatgcg tttacctgtg cacaataaat taccggctgg aagcctgggc gtttattacc
    67381 gcgatggaat gccctgcaac atgtggggaa acgaaaaatg gagctgacga tgaaacaatt
    67441 acttgcctca ccctcgctgc aattagtgac ttatcctgcg agcgccacgg cacagtctgc
    67501 agaattcgcc agtgctgact gcgtgacggg cctgaatgaa ataggtcaga tctcagttag
    67561 caatatttca ggggatccgc aggacgtgga acgtatcgtg gcgttaaagg ccgatgaaca
    67621 aggtgcgtca tggtaccgca ttattaccat gtacgaagac cagcagcctg ataactggcg
    67681 cgtacaggcg atactgtatg catgagtgtc atctacagca aatgaacaat gccggatgcg
    67741 gcgcgagcgc cttgtccggc ctacaatttt cacatatttc attgagttaa tcgaaaccag
    67801 cgtcgcatca gtcgtatacg cttacacaca cactcccccc gtcgcccgca gcaataaatc
    67861 attctggatc tgctctgaca accgtacgcc gccgcgcgta tctaacatca cctgacacca
    67921 cgcctgtgcc attggcggag aggcatattt caacatttgc gcaccgcagc ccagcaggaa
    67981 tagctgatga gtaatctctc gccccaattc ttcagctggc ttgcgcagct gctgctgtaa
    68041 acgacgaacc gcgcgatcaa aatagcgatc ctgccctttc acttccacaa acgcttccga
    68101 caataagtcg tatacgcccg cttgcttatt gagaacgcgc agcacatcca ggcacataat
    68161 attgccggaa ccttcccaaa tactgtttac cggcatctcc cggtaaagcc gcggcagctc
    68221 gctctcctcg caataaccaa tgccgcccag cacctccatc gcttcggcca caaacggcat
    68281 acctcttttg cagatcacaa attttgccgc aggcgtaaat aaacgcgccc acagggcttc
    68341 tttggcatcg gcacgccggt cccacgctcg cgcaagacga aacagcaacg ccgtttgccc
    68401 ttcaagctga agtgccatgc gacttaagac atgacgcata aggggctgtt ggatcaatgg
    68461 attaccaaaa acatggcgtt gatgtgcatg ataaatcgcc agcgaaaatg cacggcgcat
    68521 catggcatgg ctacccaggg cgcaatcaaa acgcgtcatc ccacccattt tcaggatcag
    68581 acgaattcct tccccttcct gccccaacaa ccagccaatg gcatcctgaa actccacttc
    68641 gcagctggcg ttagagcgat tacccagctt atctttcagc cgctcgaggc gaatcgcgtt
    68701 gcgttgcccg tcaggcaaaa agcgcggcac aaaaaagcag gacaaaccgc ccgtagtctg
    68761 cgccagcacc agatgcgcat cgctttgcgg caccgagaaa aaccatttat gccccaccag
    68821 ccgataagag ccatcttcca ggcgctctgc gcgggtggtg ttgctcatga catcggaacc
    68881 gccctgcttt tccgtcattc ccatgccaat caacaaaccg cgtttttgcc cacctggcaa
    68941 taagtgagaa tcgtagcgat cgctcagcag cggcgtggtc cagtcctgaa acggcgcggg
    69001 taacatctgt aacagcaatg gcgtggcggc aaaggtcatg gttatcggac ataacgaccc
    69061 tgcctcaacc tgtgcgtgca acataaaacg cgccgcgcgc gccacaaatg cgccggagcg
    69121 agcgtcttct tcccaggcaa gattgtgcac ccgattggta catagcgcct gcatcagcag
    69181 gtgccaggcg gggtgaaaac gcacatcgtc cagacggcgt ccttgcgcat cgtagcgcaa
    69241 taattcaggc ggattcacat tcgccagccg ccccagttca agggattcag ccgttcctaa
    69301 ctgctgacca atactggcta gaaaatcgct atcccagcca gcaccttcac gcgttaccgc
    69361 ttcgcagagc gcgccatcag acaggtataa gttgctgtta tttaatggta taggttgatt
    69421 aaaaacggtg tgagtttgcc agtgcactgt gtctccctcc atcaatggca gtcaccatta
    69481 gtatggtcac tgccatggat tcatgacaga aagagattgc taaaacattc ttatccagca
    69541 atgtaatgcg gaacgaaacg tgaggtgtct ttggtgatca gtgtgttatc ttcacggatc
    69601 cccattccgc acgcttcatc atcgacaatc cagctaccga tgagtgtgta gctatcgcca
    69661 aatcgcggca gaggttgaaa cgcctggtag atcatcggtt catcggcgta atcaccatca
    69721 gcgtggtcaa cgacgttatt ctgaccgtcg aaaatggtga cgtttccgcc ttcgcgcgag
    69781 tagatcggtt tacgcacata gctttcgcca gcggcaatct gcgatttttc accctcaaac
    69841 caggatgcaa gaaggttagg atgaccaggg aagaagcgcc aaagcagcgg cattagccct
    69901 ttattactca agatactttt ccataacggc tccacccatt gctcgcgacg cttgcacagc
    69961 agcggaccgt tatcgtcacg catcatccac tccagcggat acagcttaaa tgcacgctgg
    70021 atgacattat catcaagatc ggtcagtaca ccgccgacgc ccaaaccgag atcttcaatg
    70081 tagataaacc gcgactcctg ccctgcctgc tgggcgcagt cctgcaagta cagcacggta
    70141 gtcctgtctt catcggtgtc ctgacagcag cagaaataaa acggctcccg gctataaagc
    70201 tcgctaaagc gtgaaatcag gcgttcctga atggcattgt actgatcggc atcacgcgga
    70261 ataatgccgc tgcgccgggc atcctccagc cacaaccact ggaaataagc cgactcatac
    70321 aacgaggtcg gcgtatcggc gttgtactcc agcagcttca ccggcgcatt gccacaccag
    70381 gcaaaatcca tccggccata cagcgaagga tcgcgtgcgc gccagctttc ggcgatcaca
    70441 tcccagtaca acggcgggat cgccagttgc gtcaggatct cttcgtcttt aaccgcgcga
    70501 tccaccacct caaggcacat ctgatgcagt tccgcagtcg gtttttcgat ctgctcttca
    70561 atctggcgca gagtaaaacg gtaagcccga ctctcgtccc aatagatttc attgtcgatg
    70621 atatgaaagt cgaaaccgtt gttagcggcg atctggtcca gatcccgtcg cacaggaacg
    70681 ttgtgtctca gcatgattag cctccccaat gcccacgggc gctggaagaa cgaccatagc
    70741 cgccgcgcga aacggttgac gcttttttgg tggtaaagcc gcctgaagag taagactctt
    70801 ttttgccaga accggagcgc caggagtaat caccggaagt gttgcgccag acggggcggg
    70861 aagcaaatga ggatccgccg ctgttataga cgaacggctc atcgcgatct ttacgaataa
    70921 ctcggcttaa caaaaatcca gaaacgaccg ggatccaact ctgttcaaca ttgtcgtagt
    70981 agcaattttc gtacttagac tgacaattct gctgagtcat attcttcgga acatcggcat
    71041 aaaatgccgc tttggcgttg ttccagccac gcgcgcaaat gtcggcatta ttaccgtcat
    71101 caatacaatc ctgcactgtc gaataaaacg ttccgtcgcc gtcgttatcg acatcgccac
    71161 tttcactcca tcctttgact attaaaaaaa cggcaccgcc cattagcacc aacgttaagt
    71221 atttttgtgc gtagcgattg cggcgcggct caaaaggatt atgcggtctt ccaatgcgac
    71281 tgatcgctcc gtgaccaatt ttactgttat ttcttgattt gcgttttctg gccatgatcg
    71341 tccattacca tgtcatacaa gctgcgttaa aaataccacc agccagtgcg gcggttccca
    71401 taaacattcc tgctgcggta ttgtgattaa taattttttc gcttaatgcg ggcatataaa
    71461 gtctgacacc agcaaaaacg agtaactgaa tcaccagtgc aatcccgccc caggcgaaat
    71521 agtctggaat actcaccgca ttgattgccg cactggataa ggggatcacg taacccaaca
    71581 atgtaccgct gaatgccagt gacgccgcgg tattattgtt tttgattaat tgccattcgt
    71641 tgtgcggtgt aattttggag tagataaaca gaaaaataat caccatagcc acgccaataa
    71701 aaaaataggc actaaaggca agaagtgaat ccagtatatg cattgtaaac gtccttgtaa
    71761 ttaaccaata atatgaagtg atgtcagcgg gatatcgaca cccaacgcgc gcgaaaataa
    71821 ccactctggc tcgccgagat cgttaaaaga ttcctcacca tttaacagca aatattcgta
    71881 agtatcttcg gttacttggc gttggtagcc catggtaaaa ttatggacct cccatttggc
    71941 atggttttga ttttctactt tttccagcat gtagacgggt tcgatatttc ccggttcttc
    72001 gctgttaaaa aatcgctgcc agcgtttttc ctgccagttt aagatcattg cccccatcac
    72061 tttggcgttg atcgcctcgc gccagtgact ctctttactg ataccgtagc tctcttcata
    72121 gacaaagagc ttgatatcat caatgtcatc aatatcttcg ccgccggtgg tattgatttg
    72181 cagaaattca tcgcctgaag tgtagtagcg gaaaatctga ctaccgccgc ccagatcgat
    72241 gtggctgaca gcggctaccg taaattcctc acccggcagc gcaatcagca attcatcttc
    72301 cagcaaacga aacgctaacg tgtcgagcgt aaagccacta ttgagatgaa gtcccagcgg
    72361 accgcgagcg atagcaggct tattatcctt gccaaacaga cgctggaaaa aaccagacat
    72421 attttatcct taaaatagtt gccagccttt tagcgaggct ggcaaaaaaa ttactcgccc
    72481 tgttggcgtt gcagtcttgc taatacatcc tgggcgctac ttttattgct accgccaatt
    72541 ccggcttccg ccagcttttc atcaagatcg cgaccgtctg cgactttttc caactgtgca
    72601 gcagcatcca ggcgagcctg acgttcggcc tgacgcgttt gcaggcgttt taaggattct
    72661 gccgctgtcg aaacgctgga agatgcgcca acggtagagg ttgttacagc ctgttgtgca
    72721 cgctgcatgg cttcagtggc tttaacgact tccatttgct gctcaaactg agcgatacgc
    72781 tgcgctgtcg ctgtaactgc tttttccacg ccatcacggg agacttccag attcgacaac
    72841 acttgctctt cagcggtaat gagattctca aggcgcgcga tttcttcagc aacttcgtta
    72901 atcaacgacg gattaacgtt cttgcttaac gcttccagcg cacgggcttc cagactggct
    72961 ttgcgctcac gtaaatcttt cagcttatcg tgacttaatt tcacccgcgc cagcagatca
    73021 acgcgagatt ttccggcttt atcgagttca gctttagcgt cacgaatatg ctgttccagc
    73081 atgcgcacgc cctgggtttc ttcaatggat tcttccgcct gggagataaa cgatttcccc
    73141 agcgtaaata aactttttaa aattcccata aatacccgtc cttgtaatta gtgtgaatat
    73201 tcttctgtaa tttcagccag atccaatgcg ttatctacct gcgaggttat ctcaagcagg
    73261 atatcttcaa gagaagattt aagcgataac gccccgaaaa caatgtaata ctcttcctgt
    73321 tgcacgctgg agattcctac cgatgacaac ggcatcatct tctgatttct taataagaag
    73381 gtattaaatt catctggatt gctgatacta cttaccggac aaataaaggt ttcgataatc
    73441 atttggcggg aagtaaaaag aatattgatt tgcaaatcgc cataatcatt cattttaata
    73501 attaatgcgc tctcgctatt tgtcacatca atattttgtt caggtacagt ttgcagcgcc
    73561 gtcgccagcg ccaacggatt ccatgtcata tattattcca tatagattta gtttaaatat
    73621 taataaaatg aatatttgca gtacgtaatt atcttaccag ctatagacaa aaaaaaacca
    73681 tccaaatctg gatggctttt cataattcag acgaactagc tgcgctgacg aaccgcttca
    73741 aataagcaaa ttccggttgc aaccgaaacg ttcagggaag aaacacttcc tgccattggg
    73801 atgctgatca actcatcgca atgttcacgg gtcaggcgac gcataccttc accttccgcg
    73861 cccatcacca gcgccaggcg tccggtcatt ttgctctgat agagtgtatg atccgcctcg
    73921 cctgccgtac cgacgatcca gatattctct tcctgcaaca tacgcatggt gcgcgcaagg
    73981 ttagtcaccc gaatcagtgg aacgctttct gccgcgccgc aggctacttt tttcgccgta
    74041 gcgttgagct gtgcggagcg atctttcggc acaatcaccg cgtgaacgcc agcagcgtcc
    74101 gcgctacgca ggcacgcgcc gaggttgtgc ggatcggtta caccgtcgag gatcagcagg
    74161 aacggttgat cgagcgaagc gatcagatcc ggcagatcgt tttcctgata ctgacgtcct
    74221 ggcttcacgc gggcgataat gccctgatgc acggcaccgt cgcttttctc gtcgagatat
    74281 tggcggtttg ccaactggat aaccacgccc tgagactcaa gggcgtgaat cagcggtaac
    74341 agacgtttat cttcacggcc ttttaaaata aagacttcct gaaaacgttc aggggcgcgc
    74401 tccagcaggg cctgcactgc gtggatgccg taaatcattt cgctcattaa tgtactcgtt
    74461 gtttacgttt tgcctgatgc actacgttta tccggcctac atgatctctg caatatattg
    74521 aatttgcgtg attatgtagg ccggataagg cgttcacgcc gcatccggca tgaacaaagc
    74581 gcattttgtc agcaatctaa ccctcttctt ttaaagaggg tattgatcac tctgccactt
    74641 ttttcttcgc cgcacgcttc gctttggtcg ctgcggctat tttctgcgtt ttcgccgatg
    74701 gctttttcgc ttttctcgcg tctttcttcg ccgctttcgg cttcgttttt ttctcaccgc
    74761 ggaaggcgct gtctggctca aagtttacct ttttaccgac ctgacgacgc ttgccgcctt
    74821 ttttgcctgc atcgcctttt ttcgctttct cgcgcgccgt tttaccgacg ttgcgcggtg
    74881 cgcgttcact ggagatcaga ctaaagtcga ttttgcgctc gtccatatta accgcttcga
    74941 cgcgaacttc cacgcgatcg cccaggcgat aagtctggcc gctggattcc cccatcaggc
    75001 gttgccctac ctggtcaaag cgatagtagt cattgtccag cgaagagaca tggaccagac
    75061 catcaatgaa caagtcgtcc agacggacga agaagccaaa gccagtgacg ctggaaatta
    75121 cgcctttaaa gacgttacct acctggtcga gcatgaagtc acacttcagc cagtcagcga
    75181 catcgcgcgt tgcttcgtcg gcacgacgtt ccgccatcga acagtgctga cccagttgca
    75241 acatctcttc catcgaataa tggtagccgc cggtttcagt ggtgttgccc tgatgcccct
    75301 gctctttcga cagcagatat ttaatggcgc ggtgcagcgt caggtcagga taacgacgaa
    75361 tcggcgaagt aaagtgcgca taggactgca atgccagacc gaagtgacca cggttttctg
    75421 gatcgtaaat cgcctgtttc atcgagcgta gcagcatggt ttgcagcatt tctgcatcag
    75481 gacggtcggc aaccgactcc agcagttccg cgtagtcacg cggttccggc ttgttaccac
    75541 ccggcagctc cagccccagc tccgccagca ctgaacggaa agaggtaatc gcttcggtgc
    75601 tcggcttgtc gtgaatacgg aacagtgccg gttctttcgc tttctcaacg aaacgcgccg
    75661 ccgagatatt cgccagaatc atgcactctt caattaattt gtgcgcgtcg ttacgctggg
    75721 tctgttcgat acgttcaata cggcgttcag cgttgaaaat gaacttcgct tcttcgctct
    75781 caaatgagat cccaccgcgt tcttcacggg ctttatccag cactttatag aggttatgca
    75841 actcttcgag atgcttaacc agcggggcgt actgctcgcg cagatcctga tcgccctgca
    75901 gaatatgcca gactttggtg taggtcagac gcgcgtgaga gctcatcacc gcttcgtaga
    75961 atttgtagcc cgtcaggcgg cctttcgacg aaaccgtcat ctcgcacacc atacacaggc
    76021 ggtctacctg cgggttgagc gaacacaggc cgttagagag cacttccggc agcatcggga
    76081 taacctgcga agggaagtac accgacgtgc cacggttacg cgcttctctg tccagcggcg
    76141 ttggcggacg cacatagtag ctgacgtcgg caatcgcgac ccataaacgc cagccgccgc
    76201 cgcgtttttt ctcgcagtaa actgcatcgt caaagtcacg ggcgtcttcg ccatcaatgg
    76261 tgaccagcgg taaatcgcgc aaatcgacac ggcccgcttt tgcttcttcc ggcacttctt
    76321 ctttcagccc ggcaacctgt tgctcaacag cctgcggcca gatgtacgga atttcatggg
    76381 tacgcagagc gatatcaacc gccatgccgg tgcccatatt atcgccaagg acttcgacga
    76441 ttttacccac cgctttggtg cggcgagtcg gacgctgagt cagttcgact acgaccacaa
    76501 agcccatccg cgcgcccatg atctgatcgg gcgggattaa gatatcgaag ctcagacggc
    76561 tatcgtcagg aaccacaaag ccgacgcccg cttcggtaaa gtagcgacca acaatctggc
    76621 tggtttttgg caccagtacg cggacaatac gcgcttcacg acgaccttta cggtcagcgc
    76681 ccagcggctg agccagcacc tgatcgccat gaatgcaggt tttcatctgc tcgctggaga
    76741 gatacaaatc atctttacgc ccttcaaccc gcagaaagcc gtagccatca cggtggccaa
    76801 taacggtacc tttcaccagg tcgaggcgtt ccggcagcgc atagcactga cgacgagtga
    76861 agaccagttg accatcgcgc tccatcgcgc gcaggcggcg acgcaggcct tcaagctgct
    76921 cttcgccttc aatgtgcagt tctaccgcca gctcatcacg gctggccggt ttttcacgtt
    76981 tggttaaatg ttcgaggata aattcccgac tagggatggg attcgcgtat ttttcagctt
    77041 cgcgttcctg gaaaggatct tgtgacatct cggttcctcc gttgtcatct ctgatgaaga
    77101 ttttcgtcac tccaccagca ataatttata aagcggttga ttctcttcaa ccaaatcggc
    77161 aagcgtgtag ttatccagtt ccgtaagaaa actttgcacg gccttagaaa gcgcctgttt
    77221 caaccgacag gcaggtgtaa tgtggcaaaa ctcactgctg caattcacca gcgataaggg
    77281 ctccagctcg cgcaccacat caccaatacg tatcgcactc gccggtttac ccaggcgaat
    77341 gccgccattt tttccacgaa cagcagtcac gtagccggca cgactaagtt gattgattat
    77401 tttgaccata tgattacggg agacgccgta gacgtcagtc acttcagaaa tactggtcat
    77461 ccgcccttct ggcaatgacg ccatgtagat cagcgcacgt aatccgtaat cagtgaaact
    77521 cgttaactgc acatcaacct caaaagggaa atcgggaaaa aatacattta tattgatgat
    77581 aaaccagcca caagctgtgt cgctaattta tttcagttcg gggaaggaaa aaagcgagga
    77641 tttaacactg tgtcggatag cgtaatggct taaccgacac agcaatgtat cacactgtta
    77701 gcccggcagg caaaatatct gccaggcgta ccagaattac gcgtcgaacg gatcgcgcag
    77761 aatcatggtt tcagtacgat ccggaccggt agagatgata tcgatcggca caccagtcag
    77821 ctcttcaata cgcttgatgt agttcagcgc cgcctgcggc agaccgctac gatctttcac
    77881 gccgaaggtg gattcagacc agcccggcat ggtttcgtaa atcggctcta cacctttcca
    77941 gtcgtcagct gccagcggag tggtcgtcac ttcacgacca tccggcatac ggtaagccac
    78001 acagagtttc acctctttca ggccatccag aacgtccagt ttagtcaggc agaagccaga
    78061 cagggagttc agctgtaccg cacgacgaac ggcaacggtg tccagccagc cggtacgacg
    78121 acgacgcccc gtagttgcgc cgaattcgtt accctgcttg cagaggaact cgccagtttc
    78181 atcaaacagt tcggtcggga acggacctgc acctacacga gttgagtaag ctttgaggat
    78241 acccagaaca taatcaacat aacgcgggcc caggccggaa ccggtcgcca cgccaccagc
    78301 agtggtgttg gaagaagtta cgtacggata agtaccgtgg tcgatatcca gcagcgtacc
    78361 ctgcgcacct tcaaacatga cgaaatcgcc acgctgacgc gcctggtcga gcaggtcaga
    78421 aacgtcaacc accatagaag tcaggatgtc ggcaacagcc atcgtatcat ccagaacttt
    78481 ctggtaatca accgcttcag ctttgtagta gttaaccaac tggaagttgt gatattccat
    78541 cacttctttc agtttttcag cgaaggtttc tttgtcgaaa aggtcgccaa cacgcagacc
    78601 gcgacgtgct actttatctt cataagcagg cccgatacca cgaccggtgg tgccgatcgc
    78661 tttcgcgcca cgcgctttct cacgcgcgtt atccagcgca acgtgataat caaggatcag
    78721 cggacatgct tcagacagca gcagacgctc acgaacgggg atgccacggt cttccagttc
    78781 tttcatctct ttcatcagcg cggccggaga cagcacaaca ccgttaccga tgatgctggt
    78841 tacattctcg cggagaatac ctgatggaat aagatggaga acggtttttt caccgttgat
    78901 tacgagagta tggcctgcgt tgtgaccgcc ctggtagcgt acaacatatt tagcccgttc
    78961 agtcagaaga tcgacgatct tacctttacc ttcgtcaccc cattgggtgc ccagtacgac
    79021 gacgttgtta cccatttttc aaaatcaccg tttgcttaaa aatggattct accatcgctt
    79081 tttcagagtt acagcacttt ttgcactcaa aaatgacctc gatcagtctg ttttttgttc
    79141 agccaatcgt tttcctcaac atgtagtaga ccacaacgcc cgcaaccaca agtccaccgc
    79201 caaaacgacg taaaatatta tcgggcaaat tggtcatcgc agagatcatc ttcttccatg
    79261 ccttcgggta aagcatcggc cctaaacctt ccagtaccaa aaccagggca agcgccagcc
    79321 agattgtcga attcattcat tatccttata gaaaaagaaa accaccgaca tccctgagga
    79381 tgcggtggct ttattgacct gtaccgcagt cgttatatta acgcgttgcg gaagtcggcg
    79441 tcttcatgta gcggaagaaa tcgctatccg ggctcatgac catcacgtcc tgattgccag
    79501 agaagctgtt ctcataagca cgcaggctac ggatgaatgc gtagaagtcc ggatctttac
    79561 tgaatgcatc agcaaacagt ttggctgctt cggcatcgcc ttcaccacgc atgatgcggc
    79621 cctgacgctc agcttctgcc agcgttctgg tcacttcata gtcggcagtc gcgcgcagtt
    79681 tttccgcttc ttcctgacct tgtgaacggt gacgacgcgc taccgcttca cgctcggcgc
    79741 gcatacggtt gtagatcgct tcagacactt cggtcggcag gttgatctgc ttaattcgca
    79801 catcgacaac ctcaataccc agcgccgcca tactgttcgg gttgatgacc ggaactttgc
    79861 ccttcgtctc agccgttacg cgctctgccg cttcggcaat ggcgttatct gccgccgggg
    79921 tagtaacttc atcttctgta cccgcagaac cggagttcag cgcgtcacgt acttcgaggg
    79981 tcagacgacc acgggaatcg gtgacgatat ctttcacgtc caggcgacca atttcagaac
    80041 gcagacggtc agagaactta cgtttcaaca gcacttccgc ttgcgaaatg tcgccaccac
    80101 ccgttgccag gtagtaacgg ctgaaatcgc tgatgcgcca tttgatgtaa gagtcgacga
    80161 tcaggtcttt cttctctttg gtcacaaagc ggtcggcctg gttgtccatg gtctgaatac
    80221 gtgcgtcgag cattttcacc gtttcaatga acggtatctt gaaatgcaga cccggctcat
    80281 aaaccagagg tttgttgtca tcgtcacgca gtaccttacc aaaacgcagc gtaataccgc
    80341 gctcaccttc tttgacgaca aagacagaca tgtaaagcac taccagcacg atgatgataa
    80401 tcgcgataac tgacttacgc atcgttattc cccctgacgc tggtagtcgt tacgctgcgc
    80461 gttggcgcgg cgttggtcca taatatcgcc ctgactggtg gacgacgtgt tgcttgctcc
    80521 actggttgtg gaggaagagg ctggcggcag acgcagcaga ttgctggtac cgttatcgct
    80581 cttcgccgca ggggcgttac cgcctttcag catctggtct aacggcagaa ccatcaggtt
    80641 gccaccttta tcgttaacca gcactttgcg ggtgttaccc aacacttttt ccatcgtctc
    80701 gatatacaga cgctcgcgag taatttccgg cgcggcttta tattccggca gaagtttagc
    80761 aaagcgcgcc acttcaccct gagcttccag gatggtctgg gccttgtacg cacgcgcctc
    80821 ttcgaggata cgttgcgcct gaccgttcgc acgcggctga acttcgttgg tatacgcttc
    80881 tgcttcacga atgtattgct gttcgttttc acgcgcggca atcgcatcgt caaacgccgc
    80941 ttttacttct tccggcggac gagcagcctg gaagttgacg tccagcagcg tgatacccat
    81001 gtcatacgga cggatagtct cttccagttc gcgctgagta tcgctacgaa tcacggtacg
    81061 accttccgtc agaatgcggt ccatggtgta tttaccgata accccgcgca gggcgctgtc
    81121 ggtagcctga cgcaggctgt catccgggct ggtcacgcta tacagatatt tttccggatt
    81181 ggtgacgcgg tactgcacgt tcatctcaac gcgcactacg ttctcgtccg acgtcagcat
    81241 cacaccagaa gcggccagtt cacgcacggc ttccacgttc accggtttga cttcgtcgat
    81301 aaacgtcggt ttccagttca gacccggctc aaccagatgg ctgaatttac caaagcgtgt
    81361 taccacgccg cgttcggctt ctttaatggt atagaaacca ctggccgccc agataatgac
    81421 aatcgctgcc gctgcgatgg taacgacacg accgccaagc tgcgggcgcg ggccttgcga
    81481 tgaactgcca ccgccagatc cggtgccttt accgccgccc agaccaccga gctttttgct
    81541 cagtttgcgg aagatatcat ctaaatcagg tggcccttga tcgcgaccgc ctttgtttcc
    81601 atttccctca gagttgccgc caggtttgct gcttccccac gggtcgcggt cttgtccgtt
    81661 attaccgggc tgattccacg ccatgtttgt gctccatatt tgttatgcgg tgatccctgt
    81721 tgtctttcga cgccagagga tatgactcca cgcttcagac gctacgccgt tagatcaggt
    81781 aatcgatcaa cgccggttct tgtttacaga ggcgacgcca gtcaacgatc ggcatacgaa
    81841 cttgcagact tacgctgccg tcctcctcca tccactcttt ttctattgcc tgaagctgat
    81901 aaaaacgact tctcagacgc ccttcctgcg gcggcaaacg caatgtatgc tgcgccacct
    81961 cgccggaaag ccgctccgtc aaagcctgaa aaagctgtgg tatccccgct ccggtctgtg
    82021 cggaaagcca gacacggatc ggtttgttct cttcgtcccg atcaatacgc ggttcgaaat
    82081 cttccagcat atcgatcttg ttcatcacca gcagggttgg gatctcgtga gcgtcgatct
    82141 cttcaagaac cgtattcacc gcttcgatgt tttcttgtac acgcacatcc gccgcatcaa
    82201 tgacgtgcag cagtaatgtg gcttgccgcg tctcttgtaa cgtggcttta aatgccgcca
    82261 ccagatcgtg cggcaggtgg cgaataaacc ctacggtatc tgcaagtacg gtttcaccga
    82321 catctgcaac gtcaatacgc cgcaacgtcg ggtcgagggt ggcaaacaac tggtctgccg
    82381 cgtagacccg cgcttcggtg atgcgattga aaagggtaga tttaccggcg ttggtatatc
    82441 ccaccagcga aacagtagga acgtcggctt tgatacgcga ttgccgcccc tgctcacgct
    82501 gcttttcaac tctttccagg cgtgactgta tctgcacgat gcgattacgc aacaaacgac
    82561 ggtcggtttc gagctgggtt tcacccggac cacgcaaacc tatcccgcct ttctgtcttt
    82621 caaggtgggt ccagccacgc accaggcgcg tagccagatg gcgcagctgc gccagctcaa
    82681 cctgcaactt accctcatgg gtacgcgcac gttgggcgaa aatatctaaa ataaggccgg
    82741 tgcggtcgat aacacgacac tcgcacaaac gctccaggtt acgctcttgc gccgggctca
    82801 gggcatggtc aaaaagaacg accgaagcac ccgtcgcttt gacagcttcc gcaatttcaa
    82861 ctgctttacc ttcacctaca aaatactttg ggtgcggcgc tttacggcta ccggtaatca
    82921 cctgcaatgc ttcgacaccg gcggaagaga ccagagattc aaactcctgg aggtcttcca
    82981 tatctttgtc ttgcgtaaaa tagatgtgta ccagtaccgc ctgctcacca gcatcataac
    83041 ggtcaaacaa gcgtataacc ctctaaatag atcagcgggg aacgcaggat cgctggctcc
    83101 ccgtgtaaaa aaaacagccc gaaaccttat tcggtttctt cgctgtcctg ttgcgcggaa
    83161 gtattctgcg cgctgctacc atgatggtag ttactgctgg taccgccacc ggcgttgtta
    83221 ctgtgatgag aaaccgggcg agacgggaca acagtagaaa tcgcgtgctt gtaaaccatc
    83281 tggctgaccg tgtttttcaa caggatcacg aactgatcaa aagactcgat ttgcccttgc
    83341 agcttaatac cattcaccaa ataaatagaa actggaacac gttcccgacg cagtgcgttc
    83401 aggaacggat cttgtaaaga ttgcccctta gccattctct cttttcctta tatgcttatt
    83461 tgtactttga acctttcgat tctgaaaaaa ttgcgcacga tacgtctcaa ttgtacacat
    83521 tcagcctgcg atagcaccaa caacctgtaa tacttcgtca cgcgcctgtt ctggtttttc
    83581 actgtcaagc cagtgaaccc cttcccaacc acgcagccag gttatctgcc gcttcgccaa
    83641 ctgtctcgtg gcgcaaacac ctcgataaac catttcatcg tatgagattt cgccttcaag
    83701 gtaagaccac atctggcgat aacccacgca acgaatggaa ggcaagtccg tatgcaaatc
    83761 tcctcgggca aaaagcgccc ggacttctgc ttcaaaacct gaagccaaca tctgatgaaa
    83821 acgctgctca atgcgttgat ggagcagttc acggctcgcc ggggcgatgg cgaactgatg
    83881 cacctgatac ggtagagcgt ctcctgacgt ttgcgtcagt tccgttaaag ttttacccga
    83941 aatgaaaaaa acttccagtg cccgggaaag cctttgtgga tcatttggat gaatccttgc
    84001 tgccgcaacc ggatctacct cctgaagttg acgatgcaat gactcccaac cttgctctgc
    84061 cgcctgttgc tcaattctgg cccgcacttc cgggtctgcc gacggtagcg gcgacaaccc
    84121 ttccagcaat gccttgaaat acaacatcgt accgcccact aacagtggga tccgccccgc
    84181 cgcggtgata tcggccattt ccgccagcgc atcgcggcga aaatcagcag ccgagtaagc
    84241 ctgcgacgga tcgcgaatat ccagcaatcg gtgcggcgcg gcgagtaact cttcagcgtt
    84301 cggcttcgcc gtcccgatat ccatcccttt gtaaataagg gcagaatcaa cgcttatcaa
    84361 ctctactggt aaaattttac gcagctcaat ggctaacgcc gttttaccgg aggccgtcgg
    84421 ccccatcaaa aaaatcgcct taggcaggct cgccttactg atatcactca tctttcaggg
    84481 cttttatcgc cggatgtaaa tcaacagatt gtaacagacc acccggcggc gttttcacaa
    84541 gttgcggaca taaccgttcc acgtccgcca gcagggttat ggcctgtgcc attgaccact
    84601 gcgcatgttc gctcatcaga tttcgtgcaa tccactgcgc aatattgcca ggttcgaata
    84661 cggactgctt cgccaggtag cctatcagtt caggaatcaa gatttgtaaa ttttgttggc
    84721 gtaagggtaa aggcacggcc ctgatggtca catgctgtgc atctgactgg aaatcaatac
    84781 ccaattccgc tagggcagac tgcgcttttt ctaatgccga tttttcttcg gcagaaactt
    84841 ttagccgcaa cggaatcagc agcggctggg cgcaaacggg cgcttcaccc ggcgtcaatt
    84901 gtgcctgacg tagccaacgt tctgccactg gcaaggataa aagtgaaatg ttgccatcgc
    84961 gctccagcaa cgcacagtcg gaatggacga tagtcagtac ccgaccaaaa ctctgactgt
    85021 tcgccgcaag tgcaggttcc tgcggttccg gcgcttttgg tttttgcatc ggcgcgggcg
    85081 tttgcaaaag ctggcgatac acttcacctt gctgtttctg gtagcctggc tgcgcattcg
    85141 gccagggggc agccggacga ctgcctgatg ctggcgcagg agtgtagcgc ggagctaccg
    85201 gctcacgagc tgccggttct gcaaagtgat tgcgccccgc cgccacgcgg ttttccggaa
    85261 tggaacgcgg tgcaggttgg ggttcatcgt ccagcggtag cggcgtttcc agttgctgtt
    85321 gtagcacgct cagcacgccc tgatagataa aatcatgcac cagacgcgac tgatggaaac
    85381 gcacttcgtg tttggcgggg tgcacgttga cgtccacctg atgcggatcg atctccagat
    85441 acagcacaaa tgccggttgc tgatcggccc ccagtttgtc ttcgcaggcc tggcggatcg
    85501 cgtgattgat caggcgatcg cgcatcatgc gaccgttcac gtagcaatac tgaatttctg
    85561 ccagtgcggg cgtggtgtga tttggatcgg ccacccagcc gcgtagcgtg agatcgccgt
    85621 gttgccattc aatcgccagc gcttgttcaa gaaaagcggt gccgcaaatc gcgcctaagc
    85681 gccgttcttt ttgcccgcct tccggcactg cgcggtactg acgcacaatt ttaccgttat
    85741 gcgacaggtt gatcgtgacg tcgaaacgcg ccagcgcaat gcggcggatg atctcatcaa
    85801 tgtggttaaa ttcggttttc tcggtgcgca ggaatttgcg ccgcgccggg gtgttgtaga
    85861 acagatccag cacctccagc gtcgtcccca caggatgcgc cgccggtttt accgtcacgt
    85921 tcatatcgcg cccttcggca taggcctgcc aggcttcctg ctgttctgcg gtgcgtgaag
    85981 tgagcgtcag gcgggaaacc gaactgatac tcgccagcgc ctcaccgcga aagcccaggc
    86041 tgataatggc ttcgagatcg tccagagagg cgattttact ggtggcatga cgcgccagcg
    86101 ccagcgccag ctcgtctttt ttgataccgc agccgttatc acgaatgcgg ataagtttcg
    86161 ccccaccgcg ttcgatatca atatcgatac gtgtcgcacc tgcatcgagg ctgttttcca
    86221 ccagttcttt gactaccgac gcaggtcgct cgaccacctc acctgcggca atctggttcg
    86281 ccagttgtgg cggtaagacc tgaattggca tcaatcgtcc ttagtttggc agcgtgcgat
    86341 ctggcgtcgt caccgtactg gccgtttgtg ccgttgcccc ctgcggcgca gattgcatcg
    86401 gatgcgcaag gaaataattg cgcaggcctt tgtaaatggc ttctgccagc tgttgttggt
    86461 aatcgtcgct cgccagcaaa cgttcttcgc tgttgttgct gataaaaccg gtttcgacca
    86521 gtactgatgg gatatccggc gaacgcagaa cgccgagact cgcgtgttct ggtcggcgtt
    86581 tatgtatttc gccaatgcgt tgcaactgac tgatcatact ggtcgctaca tcatacccta
    86641 cccgttggga atgaccgaac tgtaaatcca gcaccgcctg gcttaaatag gggtcagact
    86701 gactgttcgc cagcacatca cccgccccac ccagcagctc cgactgtttc tcgtgctgct
    86761 ccagccagct ggccatttcg ctgttggcgc gacggttaga gagcacccat acggaagcgc
    86821 cagtcgcact gcggttcggt gcggcatcag cgtgaatcga cacgaggaaa ttggcgtttt
    86881 gcttacgtgc cacatcactg cgccccatca ccgagataaa gtaatccccg tcacgggtta
    86941 aaacgccctt aaacatcgga tcgtcattga gcaaagtacg caatttacgc gcgatggcga
    87001 tggtgacatt tttctcccgc gtaccaccgg ggccgatagc gccagggtcc tgaccgccgt
    87061 gtccggcatc aatagcgatg ataattttat cgccagtgtt agccgtcgcg cgcgctgccg
    87121 gacgcgttac cgtattactg ctgataacac ccgtagtgcg gttactttcc gttttaaacg
    87181 gattgcgcgc cggttcgctg acgcgcggtg cgacaaccgc aggcgtttca acgcgtttcg
    87241 caaccacggg cggcggagga ggaggtggcg gcgcatcggc gttaatcgta aagacgacag
    87301 tgtaattgct gccattctgc cgcttcaccg cttcggtttt accgttttcg gtaagatcga
    87361 ccaccagccg tagcgtttgt gcatctttag gcgttccaga gcgaatcgcc ttcaccagat
    87421 tattgccgct gaacaacaac ggcagtccct gaatcacgcc cgtttgtttg atatcgagcg
    87481 ccacggtgcg tttgctttga tggctaaacg cataatcagg atcgccaata aaactcaacg
    87541 ttatccgcgc ctgttgatta ccgttagaaa cctgaatatc agagagcgtc gcggcaccca
    87601 ccggcgtgca cagcagcagc agcgtcgcta ccaaccaatt tctgatgcga tacatcatcc
    87661 cgccaccttt caaaggttaa ccggctaaac gcgccagcaa caattcaccc gcagaggaaa
    87721 ccgcactcac gcgcgcctca cggccttgtg cctgataatc aatgtgtatt tcgacatccg
    87781 ggtcaggaag aacaccagta ccttgttgtg gccactccac caggcagatg gcatcgttgg
    87841 caaaataatc gcgaatcccc ataaactcca gctcctcggg atcggcaagg cggtacaaat
    87901 caaagtgata aaccattaaa ttgtcgagcg tatagggttc gaccagcgta taagtggggc
    87961 ttttgacatt accctgatga cccagagctt gtaaaaagcc ccggctaaag gtggttttac
    88021 ctgcgcctaa atcgccatac agatagatta cggttgcgcc atcgcaggct ttcgctaccc
    88081 gctcgcccag gtctaatgtt gcctgctcat cagggagcgg aattactcga ttcatcatgg
    88141 tttttatcag tcacttccgg gttaacaata cgctgtagcg tggaaaagag atcggttgcc
    88201 agcatcccgc gcgttccaaa acgcgccgcc agtacgtcag ctgcagcacc gtgcgcgaca
    88261 cagcccgcac aggcggcatc atacggcgac agtttttgcc caagcaatgc gccaataata
    88321 ccagagagca catcgcccat gccgccgctc gccatgcctg catttccggc atcaataatg
    88381 cctaaagcgt caggatgggc ggcgaccacg gttccggcac ctttcagcac cgctacgccg
    88441 ccataacgtt gtaccagacg tttggcgcaa tgtaagcggt cactttcaat ttcagcgacg
    88501 gaacagccta acaaccgtgc ggcctcgcca ggatgcggcg tgatcacgcg attgtgacgc
    88561 ttatcgggat tgattgccag caggttcaat gcatcggcat cccacaacat cggtttgcga
    88621 aaattctcaa ctttttgcag tgcttttttc ccccactctt gctggcccag accgggacca
    88681 atcaccacca catcggccca ttccaggctt tcggtaagag agtccatcgt cagttcatgc
    88741 accatcaatt ccggtcgtgc agtcagcagc ggcgcaatgt tttcactgcg ggtcagtact
    88801 cggactaaac cagcaccagc acgtagcgcc gcttcccccg tcatacgaat agcccccgcc
    88861 gtgccgtgat cgccaccgat aattaccagc cgcccgtgat cgcctttatg cgaagtcggg
    88921 cgacgcggtt ttagccagtg agaaagttgt tctgccgaaa accgctgaat tttcgtctcc
    88981 tgacctgcca gccaactatc cagccccagt gagtcaaaat gcagttgtcc ggtaacatcc
    89041 cgcgcttttc cagtgagcaa gcctggtttc agcgcaataa aagtgatggt gtgatcggcg
    89101 ttgatcactg cgcctggcgt agcgccggtt tcagccagca ggccggaagg gatatcaacc
    89161 gccgcaatcg gcgcaggatg ggaattagcg tggtcgatta actggctaat ggattcgcgg
    89221 ggcgcttgct gcaagccggt accgagcagc gcatcaacaa tcagatctac cgattcgggc
    89281 cagacaatat tcgaagcatg gatctcgcct cccgcgttta accatgcttc gcgtgccagc
    89341 gcggcctctt ccggcaacgg tttgtcgctc tcctgggcca gcagcgtgac ctcaatgccg
    89401 accgctgtgg ccagccgcgc gaccacgtag ccatcgccgc cgttattacc atgaccgcac
    89461 agcaccagcc aatggcgggc gtcaggatac gccgaacgac acacctggaa tgcggcttcg
    89521 ccagcgcgaa gcatcagctc atagagtgta agccccagcg catctgccgc ctcacgttct
    89581 ccgcggcgga tatcgtcggc gtgccagacg gtgtgtggta tacttacggg gtttttcttc
    89641 attgtatggt ccgtcatgtc agagcccctc gatctcaatc agttagcgca aaaaattaaa
    89701 cagtgggggc tggaactggg ctttcagcag gtaggtatta ccgataccga tctcagcgag
    89761 tccgagccca aactgcaagc atggctggac aaacaatacc acggcgaaat ggactggatg
    89821 gcacgtcacg gtatgctgcg cgctcgcccc catgagttat tgcccggtac gctgcgcgtg
    89881 atcagcgtgc ggatgaatta ccttcctgct aacgccgcat ttgccagcac gctgaaaaac
    89941 cccaaactcg gctatgttag ccgttatgcg ctgggccgtg actatcacaa acttctgcgc
    90001 aaccgactca aaaagctggg cgagatgatt cagcaacatt gtgtttcgct gaattttaga
    90061 ccgtttgtcg attctgcgcc tattctcgag cgcccgttag ctgaaaaagc tgggctcggc
    90121 tggacaggta agcactcact tatcctcaat cgcgaggccg gttctttctt ctttttaggc
    90181 gaattgctgg tcgatattcc gctgcccgtg gatcaaccag tcgaggaagg atgcggtaaa
    90241 tgcgtggcct gtatgacgat ttgcccgacc ggtgccatcg tcgagccata taccgtcgat
    90301 gctcgccgct gtatctctta tctcaccatc gaacttgaag gggcgatccc ggaagagttg
    90361 cgaccgttaa tgggaaaccg tatttacggt tgcgatgact gccagcttat ctgcccgtgg
    90421 aatcgctatt cacaactcac cacagaagag gatttcagcc cgcgtaagcc gctacacgca
    90481 ccggaactca ttgagttatt cgcctggagc gaagagaagt ttttaaaagt cacggaagga
    90541 tcggcgattc gtcgtattgg tcacctgcgt tggctgcgta atatcgccgt agcattaggc
    90601 aatgcccctt gggatgaaac gattttgaca gcgctggaaa gtcgtaaagg tgagcaccca
    90661 cttctcgatg agcacatagc gtgggcgatt gcgcagcaaa tagagagacg aaatgcgtgc
    90721 atagtcgaag tgcaattgcc gaaaaaacag cgtctggttc gggtgattga aaaagggtta
    90781 ccgcgtgacg cctgattcat ccacagcttg tgaataaaaa taaaaacgca ttgcaattca
    90841 agacgaataa aatcgtcaag tgatcgactc gacaaaacgg aatcttaatt tttaacttat
    90901 ctatcaatag gttaaaaaaa tactattcac cgtgcgaagt ttctttgaaa ttaagattac
    90961 agcctgaggc tgtggataac tctgtttaca agagtttgtc agagacaacg aaaaccagca
    91021 ataacgcatc gcatcgctgt ggatatttta ttgagagaag a
//
LOCUS       DAZUDJ010000011        86320 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.011, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000011 DAZUDJ010000000
VERSION     DAZUDJ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 86320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86320
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.011"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            242..1426
                     /gene="setC"
                     /locus_tag="ACHY1N_001131"
     CDS             242..1426
                     /gene="setC"
                     /locus_tag="ACHY1N_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter"
                     /protein_id="HFS4043472.1"
                     /translation="MQKTATTPSKILDLTAAAFLLVAFLTGIAGALQTPTLSIFLADE
                     LKARPIMVGFFFTGSAIMGILVSQFLARHSDKQGDRKLLILLCCLFGVLACTLFAWNR
                     NYFILLSTGVLLSSFASTANSQMFALAREHADRTGRETVMFSTFLRAQISLAWVIGPP
                     LAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLPSIQRNIPVVTQPVEILPSTHRKRD
                     TRLLFVVCSMMWAANNLYMINMPLFIIDELHLTDKLAGEMIGIAAGLEIPMMLIAGYY
                     MKRIGKRLLMLIAIVSGMCFYASVLMATTPAVELELQILNAIFLGILCGIGMLYFQDL
                     MPEKIGSATTLYANTSRVGWIIAGSVDGIMVEIWSYHALFWLAIGMLGIAMICLLFIK
                     DI"
     gene            1537..2460
                     /gene="yicL"
                     /locus_tag="ACHY1N_001132"
     CDS             1537..2460
                     /gene="yicL"
                     /locus_tag="ACHY1N_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate/amino acid/amine transporter"
                     /protein_id="HFS4043473.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRL
                     IFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLVGTFLLVTHGNPTSLSISPAALF
                     WGIASAFAAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYARQGTNFVVNGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDW
                     LGTLLILSSVILISMDSRRRARKINRPARHE"
     gene            complement(2464..3282)
                     /gene="nlpA"
                     /locus_tag="ACHY1N_001133"
     CDS             complement(2464..3282)
                     /gene="nlpA"
                     /locus_tag="ACHY1N_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpA"
                     /protein_id="HFS4043474.1"
                     /translation="MKLTTHHLRTGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQ
                     DVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGY
                     KLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKE
                     GKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVHDS
                     VFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW"
     gene            3504..3797
                     /gene="yicS"
                     /locus_tag="ACHY1N_001134"
     CDS             3504..3797
                     /gene="yicS"
                     /locus_tag="ACHY1N_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YicS"
                     /protein_id="HFS4043475.1"
                     /translation="MKPTTLLLIFTFFAMPGIVYAESPFSSLQSAKEKTTVLQDLRKI
                     CTPQASLSDEAWEKLMLSDENNKQHIREAIVAMERNNQSNYWEALGKVECPDM"
     gene            complement(3838..5028)
                     /gene="nepI"
                     /locus_tag="ACHY1N_001135"
     CDS             complement(3838..5028)
                     /gene="nepI"
                     /locus_tag="ACHY1N_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015211 - purine nucleoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015860 - purine nucleoside transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HFS4043476.1"
                     /translation="MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLV
                     SFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIA
                     APLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFSVDGLTLVLLSFGIASFIGTSLSSFIL
                     KRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVK
                     MKKS"
     gene            complement(5239..5691)
                     /gene="yicN"
                     /locus_tag="ACHY1N_001136"
     CDS             complement(5239..5691)
                     /gene="yicN"
                     /locus_tag="ACHY1N_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HFS4043477.1"
                     /translation="MIWIMLATLAVVFVVGFRVLTSGARKAIRRLSDRLNIDVVPVES
                     MVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQIVIVDGSEQNLLQWHRILQKAR
                     LAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH"
     gene            complement(5744..7078)
                     /gene="adeQ"
                     /locus_tag="ACHY1N_001137"
                     /gene_synonym="yicO"
     CDS             complement(5744..7078)
                     /gene="adeQ"
                     /locus_tag="ACHY1N_001137"
                     /gene_synonym="yicO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeQ"
                     /protein_id="HFS4043478.1"
                     /translation="MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMV
                     YIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGIFANLPVALAPAMGLNAFFAFV
                     VVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALM
                     GLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCC
                     GLFFGDVHFSGVYSIPPDISGVIGEVDLSGALTLELAGIIFSFMLINLFDSSGTLIGV
                     TDKAGLIDSNGKFPNMNKALYVDSVSSVAGAFIGTSSVTAYIESTSGVAVGGRTGLTA
                     VVVGVMFLLVMFFSPLVAMVPPYATAGALIFVGVLMTSSLARVNWDDFTESVPAFITT
                     VMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALFALKIILVD"
     gene            7253..9019
                     /gene="adeD"
                     /locus_tag="ACHY1N_001138"
     CDS             7253..9019
                     /gene="adeD"
                     /locus_tag="ACHY1N_001138"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFS4043479.1"
                     /translation="MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLIN
                     GGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVT
                     FETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
                     VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGL
                     GGKELNAYITAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNS
                     PQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGL
                     LAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQP
                     VSASDFALQFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRL
                     APACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNG
                     QVQSHLPLPIAGLMSTDTAQLLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPAL
                     KLTSQGLFDGEKFAFTTLEVTE"
     gene            complement(9064..10455)
                     /gene="uhpT"
                     /locus_tag="ACHY1N_001139"
     CDS             complement(9064..10455)
                     /gene="uhpT"
                     /locus_tag="ACHY1N_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HFS4043480.1"
                     /translation="MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPE
                     SYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRI
                     GIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIAL
                     ALIIATLGVYQHASNEYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERK
                     IRREKKIQQLTVA"
     gene            complement(10593..11912)
                     /gene="uhpC"
                     /locus_tag="ACHY1N_001140"
     CDS             complement(10593..11912)
                     /gene="uhpC"
                     /locus_tag="ACHY1N_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter family glucose-6-phosphate
                     receptor UhpC"
                     /protein_id="HFS4043481.1"
                     /translation="MLPFLKAPADAPLMTDKYEIDARYRYWRRHILLTIWLGYALFYF
                     TRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGIINILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVG
                     EWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLAGWPLAKVLDTWHWSGFFVVISIAAGISALLLLPFLNAQAPREA"
     gene            complement(11922..13424)
                     /gene="uhpB"
                     /locus_tag="ACHY1N_001141"
     CDS             complement(11922..13424)
                     /gene="uhpB"
                     /locus_tag="ACHY1N_001141"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418124.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HFS4043482.1"
                     /translation="MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLIYWLTQAVGLTHFPLLMIGSLLTLLPVALISR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWH
                     YLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRL
                     RELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLA
                     ADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRG
                     IVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIE
                     DDGSGLPPGSGQQGFGLTGMRERVTALGGTLHISCLHGTRVSVSLPQRYV"
     gene            complement(13424..14014)
                     /gene="uhpA"
                     /locus_tag="ACHY1N_001142"
     CDS             complement(13424..14014)
                     /gene="uhpA"
                     /locus_tag="ACHY1N_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HFS4043483.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
                     ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW"
     gene            complement(14089..14379)
                     /gene="ilvN"
                     /locus_tag="ACHY1N_001143"
     CDS             complement(14089..14379)
                     /gene="ilvN"
                     /locus_tag="ACHY1N_001143"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HFS4043484.1"
                     /translation="MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ"
     gene            complement(14383..16071)
                     /gene="ilvB"
                     /locus_tag="ACHY1N_001144"
     CDS             complement(14383..16071)
                     /gene="ilvB"
                     /locus_tag="ACHY1N_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HFS4043485.1"
                     /translation="MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFRIAQS
                     GRPGPVWIDIPKDVQTAVFEIETQPAMAEKAAAPAFSEESIRDAAAMINAAKRPVLYL
                     GGGVINAPARVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPQVEAQPRAEWHQLVADLQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYEQGVFAATYPGKINFMQIAAGFG
                     LETCDLNNEADPQAALQEIINRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            complement(16177..16275)
                     /gene="ivbL"
                     /locus_tag="ACHY1N_001145"
     CDS             complement(16177..16275)
                     /gene="ivbL"
                     /locus_tag="ACHY1N_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HFS4043486.1"
                     /translation="MTTSMFNAKLLPTALSAAVVVVRVVVVVGNAP"
     gene            16840..16929
                     /gene="tisB"
                     /locus_tag="ACHY1N_001146"
     CDS             16840..16929
                     /gene="tisB"
                     /locus_tag="ACHY1N_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin TisB"
                     /protein_id="HFS4043487.1"
                     /translation="MSLVDIAILILKLIVAALQLLDAVLKYLK"
     gene            complement(17192..17266)
                     /gene="ysdE"
                     /locus_tag="ACHY1N_001147"
     CDS             complement(17192..17266)
                     /gene="ysdE"
                     /locus_tag="ACHY1N_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YsdE"
                     /protein_id="HFS4043488.1"
                     /translation="MNVSQIYARNGELFSGRICKQKRQ"
     gene            17348..18532
                     /gene="emrD"
                     /locus_tag="ACHY1N_001148"
     CDS             17348..18532
                     /gene="emrD"
                     /locus_tag="ACHY1N_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418129.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HFS4043489.1"
                     /translation="MKRQRNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGA
                     VQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVAVTTSSLTVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWN
                     WRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIG
                     GLAGIAAFEACSGVLMGAVLGLSSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQ
                     SVICCLLAGLLMWIPDWFGVMNVWTLLVPAALFFFGAGMLFPLATSGAMEPFPFLAGT
                     AGALVGGLQNIGSGVLASLSAMLPQTGQGSLGLLMTLMGLLIVLCWLPLATRMSHQGQ
                     PV"
     gene            complement(18540..19037)
                     /gene="yidF"
                     /locus_tag="ACHY1N_001149"
     CDS             complement(18540..19037)
                     /gene="yidF"
                     /locus_tag="ACHY1N_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFS4043490.1"
                     /translation="MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQRGIRSVQLI
                     PYLEFDDRGDLTAASVTAELWGKFLIALFECWVRADISRISIELFDATLQKWCGSENP
                     QPRRDCQACDWHRLCPHARQETPDSVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMEL
                     MTMLR"
     gene            complement(19034..19396)
                     /gene="yidG"
                     /locus_tag="ACHY1N_001150"
     CDS             complement(19034..19396)
                     /gene="yidG"
                     /locus_tag="ACHY1N_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HFS4043491.1"
                     /translation="MPDSRKARRIADPGLQPERTSLAWFRTMLGYGALMALAIKHNWH
                     QAGMLFWISIGILAIVALILWHYTRNRNLMDVTNSDFSQFHVVRDKFLISLAVLSLAI
                     LFAVTHIHQLIVFIERVA"
     gene            complement(19386..19733)
                     /gene="yidH"
                     /locus_tag="ACHY1N_001151"
     CDS             complement(19386..19733)
                     /gene="yidH"
                     /locus_tag="ACHY1N_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
                     /protein_id="HFS4043492.1"
                     /translation="MKISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAP
                     DFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKAMRLKEDLPYTNSLLIISLILMV
                     VAVIVMGLVLYAG"
     gene            19842..20291
                     /gene="yidI"
                     /locus_tag="ACHY1N_001152"
     CDS             19842..20291
                     /gene="yidI"
                     /locus_tag="ACHY1N_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YidI"
                     /protein_id="HFS4043493.1"
                     /translation="MGIIAQNKISSLGMLFGAIALMMGIIHFSFGPFSAPPPTLESIV
                     ADKTAEIKRGLLAGIKGEKITTVEKKEDVDVDKILDQSGIALAIAALLCAFIGGMRKE
                     NRWGIRGALVFGGGTLAFHTLLFGIGIVCSILLIFLIFSFLTGGSLV"
     gene            complement(20338..21831)
                     /gene="yidJ"
                     /locus_tag="ACHY1N_001153"
     CDS             complement(20338..21831)
                     /gene="yidJ"
                     /locus_tag="ACHY1N_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HFS4043494.1"
                     /translation="MKRPNFLFIMTDTQATNMVGCYSGKPLNTQNIDSLAAEGIRFNS
                     AYTCSPVCTPARAGLFTGIYANQSGPWTNNVAPGKNISTMGRYFKDAGYHTCYIGKWH
                     LDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETF
                     TWAHRISNRAVDFLQQPARAEEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYDLGEKA
                     QDDLANKPEHHRLWAQAMPSPVGDDGLYHHPLYFACNDFVDDQIGRVINALTPEQREN
                     TWVIYTSDHGEMMGAHKLISKGAAMYDDITRIPLIIRSPQGERRQVDTPVSHIDLLPT
                     MMALADIEKPEILPGENILAVKEPRGVMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLV
                     LNLFTSDELYDRRNDPNEMHNLIDDIRFADVRSKMHDALLDYMDKIRDPFRSYQWSLR
                     PWRKDALPRWMGAFRPRPQDGYSPVVRDYDTGLPTQGVKVEEKKQKF"
     gene            complement(21828..23543)
                     /gene="yidK"
                     /locus_tag="ACHY1N_001154"
     CDS             complement(21828..23543)
                     /gene="yidK"
                     /locus_tag="ACHY1N_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HFS4043495.1"
                     /translation="MNSLQILSFVGFTLLVAVITWWKVRKIDTGSQQGYFLAGRSLKA
                     PVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRGI
                     ATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHG
                     AAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFM
                     QGIEQLTTVHAEKLNSIGGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLA
                     EGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPMVGFFG
                     AVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVLV
                     APWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITI
                     NYLVKFDFHFLYVLACTFCINVVVMLVIGFIKPRSTPFTFKDAFAVDMKPWRNVKIAS
                     IGILFAMIGVYAGLAEFGGYGTRWLSMISYFIAAVVIVYLIFDSWRHRHDPAVTFTPD
                     AKDSL"
     gene            23710..24603
                     /gene="yidL"
                     /locus_tag="ACHY1N_001155"
     CDS             23710..24603
                     /gene="yidL"
                     /locus_tag="ACHY1N_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418136.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFS4043496.1"
                     /translation="MNGKLQSSDVKNETPYNIPLLINENVISSGISLISLWHTYADEH
                     YRVIWPRDKKKPLIANSWVAVYTVQGCGKILLKNGEQITLHGNCIIFLKPMDIHSYHC
                     EGLVWEQYWMEFTPTSMMDIPVGQQSVIYNGEIYNQELTEVAELITSPEAIKNNLAVA
                     FLTKIIYQWICLMYADGKKDPQRRQIEKLIATLHASLQQRWSVADMAATIPCSEAWLR
                     RLFLRYTGKTPKEYYLDARLDLALSLLKQQGNSVGEVADTLNFFDSFHFSKAFKHKFG
                     YAPSAVLKNTDQHPTDASPHN"
     gene            complement(24600..25414)
                     /locus_tag="ACHY1N_001156"
                     /pseudo
     CDS             complement(24600..25414)
                     /locus_tag="ACHY1N_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312649.2"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25414..27030)
                     /locus_tag="ACHY1N_001157"
     CDS             complement(25414..27030)
                     /locus_tag="ACHY1N_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312650.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4043497.1"
                     /translation="MLSQIQRFGGAMFTPVLLFPFAGIVVGLAILLQNPMFVGESLTD
                     PNSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVMVSFLTWNYFI
                     NAMGMTWGSYFGVDFTQDAVAGSGLTMMAGIKTLDTSIIGAIIISGIVTALHNRLFDK
                     KLPVFLGIFQGTSYVVIIAFLVMIPCAWLTLLGWPKVQMGIESLQAFLRSAGALGVWV
                     YTFLERILIPTGLHHFIYGQFIFGPAAVEGGIQMYWAQHLQEFSLSAEPLKSLFPEGG
                     FALHGNSKIFGAVGISLAMYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFI
                     SPLLFAVHAVLAASMSTVMYLFGVVGNMGGGLIDQVLPQNWIPMFSNHADMMLTQIAI
                     GLCFTLLYFVVFRTLILQFNMCTPGREDAEVKLYSKAEYKASRGQTTAAEPKKELDQA
                     AGILQALGGVGNISSINNCATRLRIALHDMSQTLDDEVFKKLGAHGVFRSGDAIQVII
                     GLHVSQLREQLDSLINSHQSAENVAITEAV"
     gene            27326..28042
                     /gene="yidP"
                     /locus_tag="ACHY1N_001158"
     CDS             27326..28042
                     /gene="yidP"
                     /locus_tag="ACHY1N_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4043498.1"
                     /translation="MIYKSIAERLRIRLNYADFTLNSLLPGEKKLAEEFAVSRMTIRK
                     AIDLLVAWGLVVRRHGSGTYLVRKDVLHQTASLTGLVEVLKRQGKTVTSQVLIFEIMP
                     APPAIASQLRIQINEQIYFSRRVRFVEGKPLMLEDSYMPVKLFRNLSLQHLEGSKFEY
                     IGQECGILIGGNYESLTPVLADRLLARQMKVAEHTPLLRITSLSYSESGEFLNYSVMF
                     RNASEYQVEYHLRRLHPEKS"
     gene            complement(28039..29700)
                     /gene="yidE"
                     /locus_tag="ACHY1N_001159"
     CDS             complement(28039..29700)
                     /gene="yidE"
                     /locus_tag="ACHY1N_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HFS4043499.1"
                     /translation="MSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVG
                     HFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     IGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEMVDQMGMSY
                     AMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIKTINIRVENPNLHD
                     LAIKDVPILNGDKIICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQ
                     EVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASGD
                     ISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVP
                     GFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKS
                     GGDFVNTLVNGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPP
                     ALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG"
     gene            complement(29897..30325)
                     /gene="ibpB"
                     /locus_tag="ACHY1N_001160"
     CDS             complement(29897..30325)
                     /gene="ibpB"
                     /locus_tag="ACHY1N_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709512.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small heat shock chaperone IbpB"
                     /protein_id="HFS4043500.1"
                     /translation="MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAEN
                     MEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS"
     gene            complement(30437..30850)
                     /gene="ibpA"
                     /locus_tag="ACHY1N_001161"
     CDS             complement(30437..30850)
                     /gene="ibpA"
                     /locus_tag="ACHY1N_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small heat shock chaperone IbpA"
                     /protein_id="HFS4043501.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN"
     misc_feature    complement(30844..30916)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01832"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ROSE (Repression Of Heat Shock gene Expression)
                     occurs in the 5'-region of heat shock genes and acts as an
                     RNA thermometer to modulate expression; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF01832"
     gene            31156..31488
                     /gene="yidQ"
                     /locus_tag="ACHY1N_001162"
     CDS             31156..31488
                     /gene="yidQ"
                     /locus_tag="ACHY1N_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HFS4043502.1"
                     /translation="MIRNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGDDETNWGTKSLAILDMPFTAVMDTLLLPWDVFRKDSSVRSRVEKSEANAQATNAVI
                     PPARMPDN"
     gene            complement(31490..32704)
                     /gene="yidR"
                     /locus_tag="ACHY1N_001163"
     CDS             complement(31490..32704)
                     /gene="yidR"
                     /locus_tag="ACHY1N_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312656.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HFS4043503.1"
                     /translation="MKQITFAPRNHLLTNTNTWTPDSQWLVFDVRPSGASFTGETIER
                     VNIHTGEVEVIYRASQGAHVGVVTVHPKSEKYVFIHGPENPDETWHYDFHHRRGVIAE
                     GGKVSNLDAMDITAPYTPGALRGGSHVHVFSPNGERVSFTYNDHVMHELDPALDLRNV
                     GVAAPFGPVNVQKQHPREYSGSHWCVLVSKTTPTPQPGSDEINRAYEEGWVGNHALAF
                     IGDTLSPKGEKVPELFIVELPQDEAGWKAAGDAPLSGTETTLPAPPRGVVQRRLTFTH
                     HRAYPGLVNVPRHWVRCNPQGTQIAFLMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQ
                     SAFNWHPSGEWLGFVLDNRIACAHAQSGEVEYLTENHANPPSADAVVFSPDGQWLAWM
                     EGGQLWITETDR"
     gene            32805..33869
                     /gene="cbrA"
                     /locus_tag="ACHY1N_001164"
     CDS             32805..33869
                     /gene="cbrA"
                     /locus_tag="ACHY1N_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418145.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin M resistance lipid reductase CbrA"
                     /protein_id="HFS4043504.1"
                     /translation="MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSK
                     PCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHA
                     FDLWMKSLIPTSVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSM
                     VRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY
                     PMKDGQTRFTTLKEKMSAFQFQFGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG
                     FISASSLEGISYALDSADILRAVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA
                     PALRKWIMRSGMAHIPQLKD"
     gene            complement(33866..35191)
                     /gene="dgoT"
                     /locus_tag="ACHY1N_001165"
     CDS             complement(33866..35191)
                     /gene="dgoT"
                     /locus_tag="ACHY1N_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4043505.1"
                     /translation="MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICY
                     VDRANLAVASAHIQEEFGITKAQMGYVFSAFAWLYTLCQIPGGWFLDRVTYFIAIFGW
                     SVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQ
                     FVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDY
                     IRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFFLTWFPN
                     YLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPIICGLL
                     ISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAG
                     GLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG"
     gene            complement(35266..36414)
                     /gene="dgoD"
                     /locus_tag="ACHY1N_001166"
     CDS             complement(35266..36414)
                     /gene="dgoD"
                     /locus_tag="ACHY1N_001166"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008869 - galactonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009063 - amino acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HFS4043506.1"
                     /translation="MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAA
                     VHELGDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPV
                     WQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAV
                     DAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAE
                     YYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAE
                     AYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFS
                     MVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW"
     gene            complement(36411..37028)
                     /gene="dgoA"
                     /locus_tag="ACHY1N_001167"
     CDS             complement(36411..37028)
                     /gene="dgoA"
                     /locus_tag="ACHY1N_001167"
                     /EC_number="4.1.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HFS4043507.1"
                     /translation="MQWQTKLPLIAILRGIKPDEALAHVGAVIDAGFDAVEIPLNSPQ
                     WEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGM
                     TVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPE
                     NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ"
     gene            complement(37012..37890)
                     /gene="dgoK"
                     /locus_tag="ACHY1N_001168"
     CDS             complement(37012..37890)
                     /gene="dgoK"
                     /locus_tag="ACHY1N_001168"
                     /EC_number="2.7.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HFS4043508.1"
                     /translation="MTARYIAIDWGSTNLRAWLYQGDHCLESRQSEAGVTRLNGKSPA
                     AVLAEVTTDWREENTPVVMAGMVGSNVGWKVAPYLSVPARFSSIGEQLTSVGDNIWII
                     PGLCVSHDDNHNVMRGEETQLIGARALAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
                     GELHHLLLNHSLIGAGLPPQENSADAFAAGLERGLNAPAILPQLFEVRASHVLGTLPR
                     EQVSEFLSGLLIGAEVASMRDYVTHQHAITLVAGTSLTARYQQAFQAMGCDVTAVAGD
                     TAFQAGIRSIAHAVAN"
     gene            complement(37887..38576)
                     /gene="dgoR"
                     /locus_tag="ACHY1N_001169"
     CDS             complement(37887..38576)
                     /gene="dgoR"
                     /locus_tag="ACHY1N_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-galactonate utilization transcriptional
                     regulator DgoR"
                     /protein_id="HFS4043509.1"
                     /translation="MTLNKTDRIVITLGKQIVHGKYVPGSPLPAEAELCEEFATSRNI
                     IREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVR
                     NLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
                     VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMI
                     ASSTRRLKEIT"
     gene            38854..39510
                     /gene="yidX"
                     /locus_tag="ACHY1N_001170"
     CDS             38854..39510
                     /gene="yidX"
                     /locus_tag="ACHY1N_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YidX"
                     /protein_id="HFS4043510.1"
                     /translation="MKLNFKGFFKAAGLFPLALMLSGCISYALVSHTAKGSSGKYQSQ
                     SDTITGLSQAKDSNGTKGYVFVGESLDYLITDGADDIVKMLNDPALNRHNIQVADDAR
                     FVLNAGKKKFTGTISLYYYWNNEEEKALATHYGFACGVQHCTRSLENLKGTIHEKNKN
                     MDYSKVMAFYHPFKVRFYEYYSPRGIPDGVSAALLPVTVTLDIITAPLQFLVVYAVNQ
                     "
     gene            complement(39556..40368)
                     /gene="yidA"
                     /locus_tag="ACHY1N_001171"
     CDS             complement(39556..40368)
                     /gene="yidA"
                     /locus_tag="ACHY1N_001171"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFS4043511.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTG
                     RPYAGVHNYLKELHMEQPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSRE
                     VGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAI
                     GDQENDIAMIEYAGVGVAMDNAIPSVKEVANFVTKSNLEDGVAFAIEKYVLN"
     gene            complement(40483..40881)
                     /gene="yidB"
                     /locus_tag="ACHY1N_001172"
     CDS             complement(40483..40881)
                     /gene="yidB"
                     /locus_tag="ACHY1N_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418153.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidB family protein"
                     /protein_id="HFS4043512.1"
                     /translation="MGLFDEVVGAFLKGDAGKYQAILSWVEEQGGIQVLLEKLQSGGL
                     GAILSTWLSNQQGNQSVSGEQLESALGTNAVSDLGQKLGVDTSTASSLLAEQLPKIID
                     ALSPQGEVSPQANNDLLSAGMELLKGKLFR"
     gene            complement(41121..43535)
                     /gene="gyrB"
                     /locus_tag="ACHY1N_001173"
     CDS             complement(41121..43535)
                     /gene="gyrB"
                     /locus_tag="ACHY1N_001173"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFS4043513.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET
                     EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQ
                     TVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFI
                     TGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYK
                     GLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            complement(43564..44637)
                     /gene="recF"
                     /locus_tag="ACHY1N_001174"
     CDS             complement(43564..44637)
                     /gene="recF"
                     /locus_tag="ACHY1N_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFS4043514.1"
                     /translation="MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDG
                     HKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQ
                     RNAALRQVTRYEQLRPWDKELIPLAEQISTWRAQYSAGIAADMADTCKQFLPEFSLTF
                     SFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            complement(44637..45737)
                     /gene="dnaN"
                     /locus_tag="ACHY1N_001175"
     CDS             complement(44637..45737)
                     /gene="dnaN"
                     /locus_tag="ACHY1N_001175"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFS4043515.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCE
                     NVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            complement(45742..47145)
                     /gene="dnaA"
                     /locus_tag="ACHY1N_001176"
     CDS             complement(45742..47145)
                     /gene="dnaA"
                     /locus_tag="ACHY1N_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFS4043516.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVA
                     QTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADN
                     PGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNA
                     IEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEIN
                     GVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVR
                     ELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVA
                     DLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREE
                     SHDIKEDFSNLIRTLSS"
     gene            47442..47522
                     /locus_tag="ACHY1N_001177"
     CDS             47442..47522
                     /locus_tag="ACHY1N_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043517.1"
                     /translation="MTIDKNWLNRSNKDPGRSLRFTHQPV"
     gene            47752..47892
                     /gene="rpmH"
                     /locus_tag="ACHY1N_001178"
     CDS             47752..47892
                     /gene="rpmH"
                     /locus_tag="ACHY1N_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFS4043518.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            47909..48268
                     /gene="rnpA"
                     /locus_tag="ACHY1N_001179"
     CDS             47909..48268
                     /gene="rnpA"
                     /locus_tag="ACHY1N_001179"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFS4043519.1"
                     /translation="MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            48232..48489
                     /gene="yidD"
                     /locus_tag="ACHY1N_001180"
     CDS             48232..48489
                     /gene="yidD"
                     /locus_tag="ACHY1N_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFS4043520.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            48492..50138
                     /gene="yidC"
                     /locus_tag="ACHY1N_001181"
     CDS             48492..50138
                     /gene="yidC"
                     /locus_tag="ACHY1N_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFS4043521.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAA
                     GSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLET
                     SPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
                     FTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYT
                     ANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            50244..51608
                     /gene="mnmE"
                     /locus_tag="ACHY1N_001182"
     CDS             50244..51608
                     /gene="mnmE"
                     /locus_tag="ACHY1N_001182"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFS4043522.1"
                     /translation="MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPR
                     YADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPG
                     LRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIAELDAVRAEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRE
                     ASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVR
                     NKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSF
                     CIGK"
     gene            51851..51925
                     /gene="tnaC"
                     /locus_tag="ACHY1N_001183"
     CDS             51851..51925
                     /gene="tnaC"
                     /locus_tag="ACHY1N_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006569 - tryptophan catabolic process
                     [Evidence IEA];
                     GO_process: GO:0031554 - regulation of termination of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase leader peptide"
                     /protein_id="HFS4043523.1"
                     /translation="MNILHICVTSKWFNIDNKIVDHRP"
     gene            52146..53561
                     /gene="tnaA"
                     /locus_tag="ACHY1N_001184"
     CDS             52146..53561
                     /gene="tnaA"
                     /locus_tag="ACHY1N_001184"
                     /EC_number="4.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009034 - tryptophanase activity [Evidence
                     IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HFS4043524.1"
                     /translation="MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSE
                     DVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQG
                     RGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFD
                     TGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAK
                     KYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPM
                     GGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYR
                     IAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIR
                     AVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIK
                     GLTFTYEPKVLRHFTAKLKEV"
     gene            53652..54899
                     /gene="tnaB"
                     /locus_tag="ACHY1N_001185"
     CDS             53652..54899
                     /gene="tnaB"
                     /locus_tag="ACHY1N_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity tryptophan permease TnaB"
                     /protein_id="HFS4043525.1"
                     /translation="MTDQAEKKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAF
                     ILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDLIGNTWNIISGITVAFVLYILTY
                     AYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWISSLAASRITSLFLGLKI
                     ISFVIVFGSFFFQVDYSILRDATSTTAGTSYFPYIFMALPVCLASFGFHGNIPSLIIC
                     YGKRKDKLIKSVVFGSLLALVIYLFWLYCTMGNIPRESFKAIISSGGNVDSLVKSFLG
                     TKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSHGGRFKTVLLTFLPP
                     ALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIV
                     ILFGITVILCWFGNVFNVLPKFG"
     gene            55031..56206
                     /gene="mdtL"
                     /locus_tag="ACHY1N_001186"
     CDS             55031..56206
                     /gene="mdtL"
                     /locus_tag="ACHY1N_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtL"
                     /protein_id="HFS4043526.1"
                     /translation="MSRFLICSFALVLLYPAGIDMYLVGLPRIADDLNASEAQLHIAF
                     SVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQG
                     LGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLF
                     WAMAMMGIAVLMLSLFILKETRPASPAASDKPRENSESLLNRFFLSRVVITTLSVSVI
                     LTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQV
                     LFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIA
                     QVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA"
     gene            56181..57140
                     /gene="yidZ"
                     /locus_tag="ACHY1N_001187"
     CDS             56181..57140
                     /gene="yidZ"
                     /locus_tag="ACHY1N_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HFS4043527.1"
                     /translation="MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLA
                     KLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELA
                     AESPLMMIMLNALSKRIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSR
                     ELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHETWNLDTFLRYPHISICWEQSDTWAL
                     DNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPL
                     PFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRETIKNLYASMA"
     gene            57297..58046
                     /gene="yieE"
                     /locus_tag="ACHY1N_001188"
     CDS             57297..58046
                     /gene="yieE"
                     /locus_tag="ACHY1N_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HFS4043528.1"
                     /translation="MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRG
                     LLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTEGECGLD
                     MELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLITLRRSVLKLTGDVLN
                     DDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPTIEKLSVWEFDGKHGWK
                     SLPDIHSRANNPTSRMMRFAQLSTVKAFSPN"
     gene            58068..58634
                     /gene="yieF"
                     /locus_tag="ACHY1N_001189"
                     /gene_synonym="chrR"
     CDS             58068..58634
                     /gene="yieF"
                     /locus_tag="ACHY1N_001189"
                     /gene_synonym="chrR"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I chromate reductase YieF"
                     /protein_id="HFS4043529.1"
                     /translation="MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIA
                     DIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLP
                     DQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQT
                     GEVIDQGTLDHLTGQLTAFGEFIQRVKI"
     gene            complement(58688..60025)
                     /gene="adeP"
                     /locus_tag="ACHY1N_001190"
     CDS             complement(58688..60025)
                     /gene="adeP"
                     /locus_tag="ACHY1N_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeP"
                     /protein_id="HFS4043530.1"
                     /translation="MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLG
                     WMLGDVHYNGIVSAPPSVMTVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH"
     gene            60192..60857
                     /gene="yieH"
                     /locus_tag="ACHY1N_001191"
     CDS             60192..60857
                     /gene="yieH"
                     /locus_tag="ACHY1N_001191"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HFS4043531.1"
                     /translation="MSQIEAVFFDCDGTLVDSEVICSRAYVTMFQEFGITLDPEEVFK
                     RFKGVKLYEIIDIVSLEHGVTLAKTEAEHVYRAEVARLFDSELEAIEGAGALLSAITA
                     PMCVVSNGPNNKMQHSMGKLNMLHYFPDKLFSGYDIQRWKPDPALMFHAAKAMNVNVE
                     NCILVDDSVAGAQSGIDAGMEVFYFCADPHNKPIVHPKVTTFTHLSQLPELWKARGWD
                     ITA"
     gene            60924..61397
                     /locus_tag="ACHY1N_001192"
     CDS             60924..61397
                     /locus_tag="ACHY1N_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043532.1"
                     /translation="MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLVLLRRIQ
                     VLPLFLLLSITTGVIPALLTGVMVACLPEKIGSQKNYRCLAGGIGGVVITEIYCAVIV
                     HIKGMASSELFENILSGDSLVVRIIPALLAGVVMSRIITRLPGLDISCPETDSLS"
     gene            61446..62033
                     /gene="cbrC"
                     /locus_tag="ACHY1N_001193"
     CDS             61446..62033
                     /gene="cbrC"
                     /locus_tag="ACHY1N_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PF03691 family colicin E2 tolerance protein
                     CbrC"
                     /protein_id="HFS4043533.1"
                     /translation="MTQNIRPLPQFKYHPKPLETGAFEQDKTVECDCCEQQTSVYYSG
                     PFYCVDEVEHLCPWCIADGSAAEKFAGSFQDDASIEGVEFEYDEEDEFAGIKNTYPDE
                     MLKELVERTPGYHGWQQEFWLAHCGDFCAFIGYVGWNDIKDRLDEFANLEEDCENFGI
                     RNSDLAKCLQKGGDCQGYLFRCLHCGKLRLWGDFS"
     gene            complement(62095..62817)
                     /gene="yieK"
                     /locus_tag="ACHY1N_001194"
     CDS             complement(62095..62817)
                     /gene="yieK"
                     /locus_tag="ACHY1N_001194"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFS4043534.1"
                     /translation="MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMY
                     EYLTTLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTITNLRNLFFTPAGIKEENIQKLT
                     IDNYREHDQKLAREGGLDLVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
                     HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASV
                     LQLHPSLMVIADKAAAAELALG"
     gene            complement(62832..64001)
                     /gene="yieL"
                     /locus_tag="ACHY1N_001195"
     CDS             complement(62832..64001)
                     /gene="yieL"
                     /locus_tag="ACHY1N_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418175.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFS4043535.1"
                     /translation="MNIKIAALTLAIASGISAQWAIAADMPASPAPTIPVKQYVTQVN
                     ADNSVTFRYFAPGAKNVSVVVGVPVLDNIHPMTKDEAGVWSWRTPILKGNLYEYFFNV
                     DGVRSIDTGTAMTKPQRQVNSSMILVPGSYLDTRSVAHGDLIAITYHSNALQSERQMY
                     VWTPPGYTGMGEPLPVLYFYHGFGDTGRSAIDQGRIPQIMDNLLAEGKIKPMLVVIPD
                     TETDAKGIIPEDFVPQERRKVFYPLNAKAADRELMNDIIPLISKRFNVSKDADGRALA
                     GLSQGGYQALVSGMNHLESFGWLATFSGVTTTTVPDEGVAARLNDPAAINQQLRNFTV
                     VVGDKDVVTGKDIAGLKTELEQKKIKFDYQEYPGLNHEMDVWRPAYAAFVQKLFK"
     gene            complement(64028..65644)
                     /gene="bglH"
                     /locus_tag="ACHY1N_001196"
     CDS             complement(64028..65644)
                     /gene="bglH"
                     /locus_tag="ACHY1N_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-specific porin BglH"
                     /protein_id="HFS4043536.1"
                     /translation="MFRRNLITSAILLMAPLAFSAQSLAESLTVEHRLELLEKALRET
                     QSELKKYKDEEKKKYTPATVNRSVSTNDQGYAANPFPTSSAAKPDAVLVKNEEKNASE
                     TGSIYSSMTLKDFSKFVKDEIGFSYNGYYRSGWGTASHGSPKSWAIGSLGRFGNEYSG
                     WFDLQLKQRVYNENGKRVDAVVMMDGNVGQQYSTGWFGDNAGGENFMQFSDMYVTTKG
                     FLPFAPEADFWVGKHGAPKIEIQMLDWKTQRTDAAAGVGLENWKVGPGKIDIALVRED
                     VDDYDRSLQNKQQINTNAIDLRYKDIPLWDKATLMVSGRYVTANESASEKDNQDNNGY
                     YDWKYTWMFGTSLTQKFDKGGFNEFSFLVANNSIASNFGRYAGASPFTTFNGRYYGDH
                     TGGTAVRLTSQGEAYIGDHFIVANAIVYSFGNDIYSYETGAHSDFESIRAVVRPAYIW
                     DQYNQTGVELGYFTQQNKDANSNKFNESGYKTTLFHTFKVNTSMLTSRPEIRFYATYI
                     KALENELDGFTFEDNKDDQFAVGAQAEIWW"
     gene            complement(65730..67124)
                     /gene="bglB"
                     /locus_tag="ACHY1N_001197"
     CDS             complement(65730..67124)
                     /gene="bglB"
                     /locus_tag="ACHY1N_001197"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglB"
                     /protein_id="HFS4043537.1"
                     /translation="MKAFPETFLWGGATTANQVEGAWLEDGKGITTSDLQPHGVMGKM
                     EPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEAEPNEAG
                     LAFYDRLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
                     QHKVALWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLIP
                     EAKIGNMLLGGLVYPLTCQPQDMLEAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNI
                     TIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNILNMIPNPHLKSSEWG
                     WQIDPVGLRVLLNTLWDRYQKPLFIVENGLGAKDSVEADGSIQDDYRIAYLNDHLVQV
                     NEAIADGVDIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGW
                     YAEVIKTRGLSLKK"
     gene            complement(67143..69020)
                     /gene="bglF"
                     /locus_tag="ACHY1N_001198"
     CDS             complement(67143..69020)
                     /gene="bglF"
                     /locus_tag="ACHY1N_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIABC"
                     /protein_id="HFS4043538.1"
                     /translation="MTELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLK
                     KTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLDEKAQQAPENDDKGNLLNRFVY
                     VISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFFPIILG
                     YTAGKRFGGNPFTAMVIGGALVHPLILTAFENGQKADELGLDFLGIPVTLLNYSSSVI
                     PIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPVTFLLVGPLSTWISEMIAA
                     GYLWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLVPLCINNFTVLGYDTMIPLLMPAIM
                     AQVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGVNLPRKYPFVIACISGAL
                     GATIIGYAQTKVYSFGLPSIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMLH
                     FITAKRQPAQGAPQEKTPEVITPPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIA
                     ILPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNV
                     GDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQISAGEPLLSII
                     R"
     gene            complement(69153..69989)
                     /gene="bglG"
                     /locus_tag="ACHY1N_001199"
     CDS             complement(69153..69989)
                     /gene="bglG"
                     /locus_tag="ACHY1N_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator BglG"
                     /protein_id="HFS4043539.1"
                     /translation="MNMQITKILNNNVVVVIDDQQREKVVMGRGIGFQKRAGERINSS
                     GIEKEYALSSHELNGRLSELLSHIPLEVMATCDRIISLAQERLGKLQDSIYISLTDHC
                     QFAIKRFQQNVLLPNPLLWDIQRLYPKEFQLGEEALTIIDKRLGVQLPKDEVGFIAMH
                     LVSAQMSGNMEDVAGVTQLMREMLQLIKFQFSLNYQEESLSYQRLVTHLKFLSWRILG
                     HASINDSDESLQQAVKQNYPQAWQCAERIAIFIGLQYQRKISPAEIMFLAINIERVRK
                     EH"
     gene            complement(70275..71000)
                     /gene="phoU"
                     /locus_tag="ACHY1N_001200"
     CDS             complement(70275..71000)
                     /gene="phoU"
                     /locus_tag="ACHY1N_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFS4043540.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVK
                     GQDFRHVGGDELDKLLAGKDSDK"
     gene            complement(71015..71788)
                     /gene="pstB"
                     /locus_tag="ACHY1N_001201"
     CDS             complement(71015..71788)
                     /gene="pstB"
                     /locus_tag="ACHY1N_001201"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFS4043541.1"
                     /translation="MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(71879..72769)
                     /gene="pstA"
                     /locus_tag="ACHY1N_001202"
     CDS             complement(71879..72769)
                     /gene="pstA"
                     /locus_tag="ACHY1N_001202"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0035435 - phosphate ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFS4043542.1"
                     /translation="MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLANALAGSGLLILWATVFGTPLGI
                     MAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKNKHG"
     gene            complement(72769..73728)
                     /gene="pstC"
                     /locus_tag="ACHY1N_001203"
     CDS             complement(72769..73728)
                     /gene="pstC"
                     /locus_tag="ACHY1N_001203"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HFS4043543.1"
                     /translation="MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGLAFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(73814..74854)
                     /gene="pstS"
                     /locus_tag="ACHY1N_001204"
     CDS             complement(73814..74854)
                     /gene="pstS"
                     /locus_tag="ACHY1N_001204"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA];
                     GO_process: GO:0035435 - phosphate ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFS4043544.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWP
                     ITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWK
                     TNIKDSSGKPLY"
     gene            complement(75168..76997)
                     /gene="glmS"
                     /locus_tag="ACHY1N_001205"
     CDS             complement(75168..76997)
                     /gene="glmS"
                     /locus_tag="ACHY1N_001205"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFS4043545.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGII
                     ENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
                     IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(77159..78529)
                     /gene="glmU"
                     /locus_tag="ACHY1N_001206"
     CDS             complement(77159..78529)
                     /gene="glmU"
                     /locus_tag="ACHY1N_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFS4043546.1"
                     /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAAN
                     ELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQ
                     RLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDT
                     NVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRP
                     GAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWR
                     RPVKKK"
     gene            complement(78880..79299)
                     /gene="atpC"
                     /locus_tag="ACHY1N_001207"
     CDS             complement(78880..79299)
                     /gene="atpC"
                     /locus_tag="ACHY1N_001207"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFS4043547.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKA
                     EEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
     gene            complement(79320..80702)
                     /gene="atpD"
                     /locus_tag="ACHY1N_001208"
     CDS             complement(79320..80702)
                     /gene="atpD"
                     /locus_tag="ACHY1N_001208"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFS4043548.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     EEAVEKAKKL"
     gene            complement(80729..81592)
                     /gene="atpG"
                     /locus_tag="ACHY1N_001209"
     CDS             complement(80729..81592)
                     /gene="atpG"
                     /locus_tag="ACHY1N_001209"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFS4043549.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAE
                     MKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(81643..83184)
                     /gene="atpA"
                     /locus_tag="ACHY1N_001210"
     CDS             complement(81643..83184)
                     /gene="atpA"
                     /locus_tag="ACHY1N_001210"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFS4043550.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(83197..83730)
                     /gene="atpH"
                     /locus_tag="ACHY1N_001211"
     CDS             complement(83197..83730)
                     /gene="atpH"
                     /locus_tag="ACHY1N_001211"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFS4043551.1"
                     /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAV
                     SEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(83745..84215)
                     /gene="atpF"
                     /locus_tag="ACHY1N_001212"
     CDS             complement(83745..84215)
                     /gene="atpF"
                     /locus_tag="ACHY1N_001212"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFS4043552.1"
                     /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(84277..84516)
                     /gene="atpE"
                     /locus_tag="ACHY1N_001213"
     CDS             complement(84277..84516)
                     /gene="atpE"
                     /locus_tag="ACHY1N_001213"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HFS4043553.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(84563..85378)
                     /gene="atpB"
                     /locus_tag="ACHY1N_001214"
     CDS             complement(84563..85378)
                     /gene="atpB"
                     /locus_tag="ACHY1N_001214"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFS4043554.1"
                     /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINID
                     SMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFIL
                     ILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(85387..85767)
                     /gene="atpI"
                     /locus_tag="ACHY1N_001215"
     CDS             complement(85387..85767)
                     /gene="atpI"
                     /locus_tag="ACHY1N_001215"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HFS4043555.1"
                     /translation="MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGG
                     LAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
BASE COUNT        21297 a        22834 c        21386 g        20803 t
ORIGIN      
        1 atcaacttgt tttattttta ctatcaaaaa tagctcattg ccttactata attaatatat
       61 aaattcggta attaattctt aacatgcttt tgctaataat ctcaattgct ggccctataa
      121 tattgcgcta gcattgcttt ctggttgtat cagcgatact caaaaattct taatacaata
      181 ctcattcgac tggtacttat ttgtaactca gttatatttt ttcgcccggt gattcagaag
      241 aatgcaaaaa acggctacca ctccatcaaa aatacttgat ctcactgccg cggcattttt
      301 acttgtcgcc tttctgacgg gtattgcggg cgctcttcag actcctaccc taagtatatt
      361 cctcgcagat gaactgaaag cccgtcctat aatggtaggt tttttcttca ccggtagcgc
      421 tattatggga attctggtca gtcaatttct ggcaaggcac tccgataaac aaggcgaccg
      481 taaattactg attctgctat gttgcttatt tggagtgctg gcctgcacgc tttttgcgtg
      541 gaatcgcaac tacttcattc tgctctcaac gggcgtactt ctgagtagtt ttgcttctac
      601 cgcaaactcg caaatgttcg ccctcgcccg tgaacacgcc gacagaacag gccgtgagac
      661 ggttatgttc agtacatttt tacgtgctca gatctcgctt gcctgggtta tcgggccacc
      721 gcttgcttat gaactggcaa tgggatttag ttttaaagtg atgtatctca ccgctgccat
      781 cgcatttgtt gtttgcggac tgatagtctg gttgtttttg ccatcaatac aaagaaatat
      841 tcctgtcgtt acccaacccg tagaaatttt accctccacc cacaggaagc gggatacgcg
      901 gctacttttt gtggtctgtt caatgatgtg ggcggcgaat aatctctaca tgataaatat
      961 gccgctattt attattgatg aactgcatct aaccgataaa ctggctggag aaatgattgg
     1021 tatcgctgcc ggtctggaaa ttccgatgat gttaatcgca ggctattaca tgaaacgtat
     1081 tggcaagcgg ctattaatgc tcattgctat cgtgagtgga atgtgttttt acgccagcgt
     1141 actcatggcg acgactccgg cggttgagct ggaattgcaa attcttaatg ccatcttcct
     1201 tggtattctc tgtggtatcg gcatgcttta ttttcaggac ttgatgcctg aaaaaatagg
     1261 ctctgcgaca acgttatatg caaatacttc acgcgtcggc tggattatcg ccggctctgt
     1321 tgacggaatt atggttgaaa tctggagcta ccatgcgttg ttctggctgg cgatagggat
     1381 gttgggtatt gcgatgattt gcctgctgtt tattaaagat atttagctca ccagtctggg
     1441 ctaagaaaaa tcggcgtggc gcaaacagag ccatcctcgc catttttgct atcatgcctg
     1501 catacataaa cgacaaaaca gtatgcagag ggaaaaatgg gttccaccag aaaggggatg
     1561 ctgaacgttc tgattgccgc cgtgttgtgg ggaagttcag gggtctgcgc gcaatacatc
     1621 atggagcaaa gccagatgtc gtcgcagttt ttgactatga cgcgtttgat attcgccggt
     1681 ttgattctac tgacgctgtc atttgttcat ggcgataaaa tcttttctat tattaacaat
     1741 cataaagatg ccattagcct gctgattttt tccgtggttg gcgcgctaac tgtacagctc
     1801 acttttttgc taaccatcga aaaatcgaac gcagccacgg caacggtgct gcaattcctc
     1861 tcaccgacga ttatcgtcgc ctggttctca ctggtgcgta aatcgcgccc gggcattctg
     1921 gttttctgcg ctattttgac atcgctggtc gggacttttt tattggtgac acacggtaat
     1981 ccgacgtcat tatcgatctc tcctgccgcg ttgttctggg gcattgcctc ggcatttgct
     2041 gctgcattct ataccaccta tccctcaacg ctaattgccc gctatggcac gttaccagtc
     2101 gtcggctgga gtatgctgat tggcggtctg attctgttgc ctttttatgc cagacaagga
     2161 acaaactttg tcgttaacgg cagtttgatt ctggcgtttt tttatttggt ggtcattggt
     2221 acgtccctga catttagtct gtacctgaaa ggagcacaat taattggcgg tccaaaagcc
     2281 agcattttga gctgtgcaga accattaagt agcgcgctac tctctttgct gttgctgggg
     2341 atcacgttca cattaccgga ctggctggga acgctgctga ttctgtcatc ggtgattttg
     2401 atttcaatgg attcccgtcg ccgcgccaga aaaataaatc gtccggcgcg gcatgagtga
     2461 gaattaccag ccaggcaccg cgccaccgtt aaaaatggtt tctgccgctt tagcgacttc
     2521 gggtgattga taagattgca gaaattcctt cacgttttct gcattcttat tatcttcccg
     2581 tgccaccaaa atattcacat acggcgaatt cttatcttca ataaatacgc tgtcgtgcac
     2641 cggagaaagc cctgtctgct gaatgtaagt ggtactgata atcgctacat caactttggg
     2701 atcatccagt acgcgcggaa gctgcgcccc ctcgagttcc ataatctgca aatgacgagg
     2761 attatcggtt atatccagcg cggtaggtaa taaccctttt ccctctttca gagtaattag
     2821 cttctctttt tgcaacagta aaagtgcgcg accaaggttg gtcgggtcgt tggggatcgc
     2881 cactgtcgcg ccttctttta tttgcgccac ggttttgatt tttttggaat aacccgccat
     2941 agggaagaca aacgtatttc ccaccgctac cagtttataa ccatgcgcct gattatcttg
     3001 ttcaagaaag ggtcgatgct ggaagacatt cgcatcaagt tcgccatgat ttgtcgcatc
     3061 gttcggtagc aacgaaccgc taaatcctac cagttcaaca tcgaggccat atttctcttt
     3121 tgccaccttt ttagcgactt ccgcgacatc ttgttctgcg ccatttataa cgccaacttt
     3181 aatgtgtttt gcatcgctgc tactctggtc gcaacctgcc agcagaattc cggccagcaa
     3241 taatgcggcc cctgtccgta gatgatgtgt tgtcagtttc atttttttat ccttttatta
     3301 atgattacct gactatagcg gtaaggtcgc tgcggtttaa aaaacgaaac gctatcgata
     3361 agaataaaaa ggaataaaag tggaatataa agtctggcac ttcttactga ccacgcaagc
     3421 gcgtttcgta cagcatgatg agagcgatga aagcaaacta cacttatgct tcattcgata
     3481 cacatttgta aaaggttgaa tccatgaaac caacgacact actgcttatt ttcacttttt
     3541 tcgctatgcc aggcatcgta tacgccgagt cgccttttag ctcactgcag tccgcaaaag
     3601 agaaaaccac ggtattacaa gatttacgta aaatttgcac gccacaggcg tcattatcag
     3661 atgaagcgtg ggaaaagtta atgttgtcag atgaaaacaa taaacaacat atacgcgagg
     3721 ccatcgtggc gatggaacgt aataatcaga gcaattattg ggaagcgttg ggtaaggtag
     3781 aatgcccgga tatgtaagaa cagcaacaac tactgaccaa cgcttcttta cctgatatca
     3841 ggatttcttc attttcacct ttgcagtaac caacaatgca gtcagcaaca tcaatgtgcc
     3901 ggacaacatc aacggcgaag tcagaccaat attatccagc gcataaccgc cgattgccgc
     3961 gccacaggta ttagcaagct gaataaccgc cacctgaata gacccggctt tttctgcctg
     4021 atcggccagc gagcgggtga tccacgttga ccagccgacg ggaaccaatg caaaagttag
     4081 cccccagata atcgccacgc cggtagcaac gattttatcg cttccccaca acgtcagtac
     4141 caacgcactc acagccagta ttaacggcgc gcctgctaag gccagtttta ccgaacgttt
     4201 aagaatgaat gacgaaagcg acgtaccgat aaagctggca atgccaaaac tcaacagcac
     4261 cagcgttaag ccatccacgc tgaatcccgc caggttcata tacaccgggc gaatatatgt
     4321 gaagaaagca aactgcccgg cgaaagacat gaagatggcg atcatccctg ccatcacacc
     4381 cggacgttgt aataagcgga aagtattttg tttctgatgc gagggttcgc ctggcagtga
     4441 aggcaatgat ttgataatcc agaaaataca cagcacgccc atcaccgccg ccgcattaaa
     4501 gacattgcgc caaccgataa gctcgcctaa aaaactgccc aacggcgcgg caatcaccag
     4561 cgcaatagaa accgcgccga agatcaccga cagcgccttc ggcaccgtac gcggcggcac
     4621 cagacgcatg gtcagcgacg ccgacatcgc ccagaacccg cccagcgcca gccccagaca
     4681 ggcacgaccg attaaaagca aactgaatga gttagcaaag gaaaccagca agcaggagag
     4741 cgtcagcaaa acggcaaaca aaataacaac gtagcggcgg tcagtagcct gaattgtctg
     4801 ggtaataaac aaactggcaa acattgccac aaaggcggtc acggtcaccg attgcccggc
     4861 aaccccttcc gaaatgccta aatcctgggc cattggcgtc aacaaactga cgggcaaaaa
     4921 ctcaacgata atcagacagg cgacacaaaa cgccaccgag aaaacggctg accagttcgg
     4981 tcgggtgatg gcatccgcgc cgcggttttc ggcaataaat tcactcatgg tgttacccgt
     5041 ggcatgtttc aggggaaaag ccgaccactt taacattgaa atgtgtgacg cacttaacgt
     5101 ttttgcaact tttacggtgt tgcttgagct ggagttaaga tcgaaacgga acagggcaaa
     5161 gattaccgga tgcggcgtga acgtcttatc cacccgacag gtcaggcgcg gtctgtaggc
     5221 tgataagacg aagcggtttt aatgcagcca gtgaacgccc tcggcaggct gaaagaacgc
     5281 gttatagcgc atctgaaaag cattaatatc ctgcatttca ggttcggttt cgcgcagaaa
     5341 acccagcgcc agcctgacct gagcatcggt aatcggcgcg gcaagacggg ctttttgtaa
     5401 aatccgatgc cattgcagca ggttctgttc gctaccatcg acaatgacaa tttgccagat
     5461 gagcaacacc tgcgcggcgt tttgcaggtg cgactcatcc gggcgatgca aataacgtaa
     5521 aaattcgtca ccggctgact ttcccatttg atcgaccatc gactccacgg gtacgacatc
     5581 gatattcagc cgatcgctga gacggcgaat cgcttttctg gccccggatg tcagcacccg
     5641 aaaaccaacc acaaacacta ccgccagcgt ggcgagcatt atccagatca tgagttctcc
     5701 tgcgtaatca gaactcatga tatctggaaa ccctcgccag ttactaatcc accagaataa
     5761 tcttcagtgc aaacagagct gcgaccacca ccacacacag gttcagatcg cgccagcgcc
     5821 cggtgcacac tttcatgatg cagtacgaca taaagccgag tgcaatccct tcggtgatcg
     5881 aaaaagtaaa gggcatcatc accgtggtaa taaacgcagg caccgattcg gtaaaatcat
     5941 cccagttaac gcgcgccagg ctcgaagtca tcagcacgcc aacaaagatt aacgctccgg
     6001 cggttgcgta aggaggaacc atcgccacca gcggtgagaa gaacataact aacaggaaca
     6061 taacgccaac cacaaccgca gtcagccccg tgcgaccacc gactgccaca ccagaagtac
     6121 tttcaatata ggcagtaaca gacgaggtgc cgataaacgc ccccgccacc gaactgacgc
     6181 tatcaacata cagcgcctta ttcatattgg ggaatttacc gttactatct attaagcccg
     6241 ctttatcagt tacaccaatt aatgttcctg atgaatcaaa taggttgatc agcataaagg
     6301 agaaaatgat accggcgagt tcaagtgtta acgcgccgct caaatctact tcaccaatga
     6361 cgccgctaat atcaggcgga atggaataga cgccgctaaa atgaacatca ccgaaaaata
     6421 atccacagca agacgtcacc acaatagaaa ccagcaccgc ggcatgaaaa tgacgtgatg
     6481 acaacacggt tataataaaa aaccctaaaa tacctaacaa cacgccgtga gaacttaaat
     6541 cgccaatcat caccagcgtg tctttattgg cgacaataac gccagtattt tttaatccca
     6601 ttaaggcgat aaataatcca attccgctgg tgataccaat acgtaaactt aagggaatgt
     6661 tggagatcat ccagtaccgg atacgaaaca gcgtgagcaa aaatagtcca actgcgcccc
     6721 agaatattgc gcccatcccg gtctgccagg agatgcccat cgcccccacg accacgaagg
     6781 caaagaaggc gttcagcccc attgccggag ccagcgccac gggtaagtta gcaaatatcc
     6841 ccatcgcaat actgccgata ccggcaatca aacaggtggt aacaaacacc actttcgggt
     6901 ccatttgtgc cgcgccgagg atttgcgggt tcacaaaaac gatgtacacc atggttaaaa
     6961 aagtggtcat ccccgcaatc aattctgtgc ggacggtggt cccatgctga ggtagtttaa
     7021 ataatcgcga aagcgtccct gattcattac tcacgtaatc ggtattgtca ttattcattt
     7081 ttttgtccat tggaggagat ttaatccctt gcttttgtaa aacaaatgac aacaacggtt
     7141 cagtgataat tatcacattt caattgcaca ttaatggata ttctttaata atctcgcgac
     7201 gtttctttat gataaataat aatcaaattg ataaaatcaa aatgagaaaa atatgaataa
     7261 ttctattaac cataaatttc atcacattag ccgggctgaa taccaggaat tgttagccgt
     7321 ttcccgtggc gacgctgttg ccgattatat tattgataat gtctctattc tcgacctgat
     7381 caatggcgga gaaatttccg gcccaattgt gattaaagga cgttacattg ccggtgttgg
     7441 cgcagaatac gctgatgctc cggctttgca gcggattgat gctcgcggcg caacggcggt
     7501 gccagggttt attgatgctc acctgcatat tgaatccagc atgatgacgc cggtcacttt
     7561 tgaaaccgct accctgccgc gcggcctgac gaccgttatt tgcgaccctc atgaaatcgt
     7621 caacgtgatg ggagaagccg gattcgcctg gtttgcccgc tgtgccgaac aggcaaggca
     7681 aaaccagtac ttacaggtca gctcttgcgt acccgccctg gaaggctgcg atgttaacgg
     7741 tgccagtttt acccttgaac agatgctcgc ctggcgggac catccgcagg ttaccggcct
     7801 tgcagaaatg atggactacc ctggcgtaat tagcgggcag aatgcgctgc tcgataaact
     7861 ggatgcattt cgccacctga cgctggacgg tcactgcccg ggtttgggtg gtaaagaact
     7921 taacgcctat attactgcgg gtattgaaaa ctgccacgaa agttatcagc tggaagaagg
     7981 acgccggaaa ttacaactcg gcatgtcgtt gatgatccgc gaagggtccg ctgcccgcaa
     8041 tctcaacgcg ctggcaccgt tgatcaacga atttaacagc ccgcaatgca tgctctgtac
     8101 cgatgaccgt aacccgtggg agatcgccca tgaaggacac atcgatgcct taattcgccg
     8161 cctgatcgaa caacacaatg tgccgctgca tgtggcatat cgcgtcgcca gctggtcgac
     8221 ggcgcgccac tttggtctga atcacctcgg cttactggca cccggcaagc aggccgatat
     8281 cgtcctgttg agcgatgcgc gtaaggtcac ggtgcagcag gtactggtga aaggcgagcc
     8341 gattgatgcg caaaccttac aggcggaaga gtcggcgaga ctggcacaat ccgctccgcc
     8401 atatggcaac accattgccc gccagccagt ttccgccagc gactttgccc tgcaatttac
     8461 gcccggaaaa cgctatcggg tcattgacgt catccataac gaattgatta cgcactccca
     8521 ctccagcgtc tacagcgaaa atggttttga tcgcgatgat gtgagcttta ttgccgtact
     8581 tgagcgttac gggcaacggc tggctccggc ttgtggtttg cttggcggct ttggactgaa
     8641 tgaaggtgcg ctggctgcga cggtcagcca tgacagccat aatattgtgg tgatcggtcg
     8701 cagtgccgaa gagatggcgc tggcggtcaa tcaggtgatt caggatggcg gcgggctgtg
     8761 cgtggtacgt aacggccagg tccaaagtca tctgccgttg cccattgccg gcctgatgag
     8821 caccgacacg gcgcagttgc tggcggaaca aattgacgcc ttgaaagccg ccgcccgtga
     8881 atgcggtccg ttacccgatg agccgtttat tcagatggcg tttctttctc tgccagtgat
     8941 ccccgcgcta aaactaacca gtcaggggct atttgatggc gagaagtttg ccttcactac
     9001 gctggaagtc acggaataat aaaaaagccc ggcgtcatgc cgggcaaaag tcaccagtta
     9061 cgtttatgcc actgtcaact gctgaatttt tttctcgcgg cggattttgc gttcttccat
     9121 caccgccact atcgccatca ggcagataca accaatcgcg gcgatatcaa gtgcggcgaa
     9181 ggtgcctgcc cagccggtaa ggccgaatac cggcgtccca tcggcaatca ttcccagacc
     9241 taacttggca aagctgtcac caatcaggta agcaaaggtg cctttaatac catcggcagc
     9301 gccaatcgct tttttaggta caaagccaac agcagccaca ccaatcaaca attgcgggcc
     9361 aaagaccagg aaacccaacg caaagagaga agccagatag atatattcgt tgctggcatg
     9421 ttgatacaca ccgagcgtgg cgataatcag cgccagcgcg atgcaggcca ccaggccacg
     9481 gcgaccgttc gccaggtcag agagccagcc ccacagcagc gtaccgacca gcgcaccagc
     9541 ttcaaacagc gtaaagccct gaatcgccac cgctttagag agtttcagtt cctggaacgc
     9601 gtatacggtt gaccactggt cgataccaat acgtaccaca tagaggaaaa tgttggcgaa
     9661 gcacagcagc cagatcactt tgtttttcag cacatactca acaaagatct gccacttggt
     9721 catatcggta gattctgtct ctttgtcctc ttcgctgatc tcctcgccga acagttcttc
     9781 agctttgccg aggccataag attccgggga gtcgctgccg taacgcaggc cgataaaacc
     9841 gacaatcagc gcgataatcg acgggaagat aaacatgccg atgacatggc catcgaacag
     9901 gtaatttgcc ccgaacagcg ccacacctgc tgcgcctgca ccgccaaggt tgtgagaaat
     9961 attccagaaa ccgaggaatg tcccgcgttt acgacgcggc gtccatttgg tgatggtgga
    10021 gtaactgcac gaaccgccgg tactctggaa aaagccgctt aaggcgtaga aggcaatcat
    10081 caggaacagg ctaaccgagc cgctgcccat actggcactg aagcccagca tacaaatggc
    10141 agacaggatc agcatgaacg gcaggaattg tttggtgttt ttgccgtcgg cgtagtagga
    10201 aaccagcgtt ttacccacgc cataagtgat ggagaaaccc aggccgatca tccccagctg
    10261 cgtcatgctc aacccgtagg tcgagatcat gtcgttctgc gcgatgttaa agttcttgcg
    10321 aatcaggtac atcgtcaggt agccgataaa gaccaccagg taggattgca tgaacggttt
    10381 gaaccacatt ttgcgccgca cttcgagcgg aaggtccagg gtcggcttgc gaacctggtt
    10441 taagaaagcc agcatgggtt actcctgaaa tgaatacctg cgtgaggcat gcattgtaaa
    10501 aatcagcagc aaatcaggcc tgagatagcg tccaggcaaa acctggaaaa tttcttagtt
    10561 ttgccggata tgaagtgaaa aggtgagatg catcacgctt cgcgcggtgc ctgggcgttc
    10621 aaaaagggca gtaacagcag tgcggaaatc ccggcggcga tagagataac cacaaaaaat
    10681 ccgctccagt gccaggtatc gagtactttc gccagcggcc aaccagcaag cgacgccccc
    10741 agataagcaa acaagccgac aaaccccgtc gccgcccctg ccgcctcttt gtgggaacac
    10801 tctgccgccg ccatgccgat taacatctgc gggccaaaga caaaaaaacc aatggtgaag
    10861 aagcaggttg cctgcatcac gtagctggca aatggcatca gccacagcga gccgactgaa
    10921 agcaaaattc cggcggcgaa aatcaaattc atcggcccac ggttgccgtt aaacaatttg
    10981 tccgagcccc aaccggctac cagcgcaccg ataaatccgc ccagttcaaa catcgtcact
    11041 gccgtattcg ccgtgaccag atcgacgccc agtgtctcgg acatatacaa attgccccag
    11101 tcgttgatcg ccgcccggac cacatagacc agcacatagc aaaacgaaag cagccagata
    11161 tacggattca gcaacacata tttggtgagg atctctttac gcgtcaaccc tgccccttct
    11221 tgttgttgag caatttccag cgcgtcgtgt cgccattcac cgaccgccgg taaacctaac
    11281 gcctgcgggc gatcgcgtag ccgccagcag agaaaaatcc ccacgactat cgccatacaa
    11341 ccagcaatca tcatcccggc acgccagccg taatgcagcg cagccgctgc catcacaatg
    11401 ggaatgagtg cgccgccgac gttatgcgcc gtgttccata atgcccacca accgccgcgc
    11461 tcggtacgtg aataccaggc cgttaacaga cgcgcacaca ccggtgaacc ccagccctgg
    11521 aaaaaggcgt tcagcaccca gagcacggca aacgcccata gcgacgtcga gaagccaaac
    11581 agaatgttga tgatgcccgt ggcgataagc cctatcccca taaaataacg ggcatttgag
    11641 cgatcgctga caatgccgga gacaaacttc gacacgccgt aggtaatgta aaacagggtc
    11701 gctaacaggc cgatatcgct acggctgagc acgccgttag caaggatttc tggtacggcg
    11761 gcgttaaaac ttttacgcgt gaagtaaaac agcgcgtaac ccagccagat ggtcagcaga
    11821 atatgccgac gccagtagcg atagcgggca tcaatttcat atttatcagt cattaatggc
    11881 gcatcggcag gcgctttcag aaacggcaac atcatcaaac cttagacata gcgttgaggt
    11941 agagaaacgc tgacacgcgt gccgtgcaga caggaaatgt gtaatgtgcc acccagcgcc
    12001 gttacgcgct cgcgcattcc ggtgaggcca aaaccttgtt gcccggaacc cggcggcaaa
    12061 ccgctgccat cgtcttcaat aaccagcatc aaccgttcat cctgctgcca gccttgcagc
    12121 gtgaccgcgc tggcatcagc atgtttcaca atgttgttca gcccttcctg gcagacacga
    12181 aacagcgtca cgcgctggtt ttcacttaat gctgattcat cgattcgcca ttcgagatgg
    12241 ctgacaatac cgcgcccttc cagctccatt tcccgcatca gtgagcggat ggcctgctcc
    12301 agggtgagat catccaactg gcgcggacgt aaccgaccca acaaacggcg caccgcgtcg
    12361 taaacgccca gcgatagttg ttcgatgagc tgcccgctct gcttcacgct ggcgttatct
    12421 gccgccagcc gctgaacaat gcccgcctga gtacgaatag cagtgatggt ctgaccgata
    12481 tcatcatgca gctcacgcgc cacatcacga cgcacgctct cttcggtttc cagcaaccgt
    12541 tcagccagat gctgattgcg cgccagttcc ttttgcagcg actggttaag ttcacgcaac
    12601 cgctggatgc cagcgcccag taacaaccct gtcagacttt gcaccagcaa cgagagcaat
    12661 aaatccaccg gatgatcgcg ccaggtttga ctggcgatca gcgcgatggc gttcatcaac
    12721 gtcgcgatca gcgccccttg ccaaccgtag tgccaggcca gcgcgataat cggcagcgcc
    12781 aggcagaatg gcgtaaagcg cgacagttcg tccggcaatc ccaactggag ccagagacta
    12841 ataacaaaca acagcaagta ccagaccaga tgccgcccgc gccagttgat cggttgagaa
    12901 accagtgacg ggccgagcgg cagccaggtg ttattggcga gatagtgcca gaacaccaga
    12961 catatcgggg ccagcgtcag gccgccagtt aaagtcagca acagcgcatt ccacgactct
    13021 ttgccgtgcc aaagccaggg cagcgactgc aacaacgccg ccgccgttaa cgccgccccc
    13081 tgtaacagca aggtgcgcca gtcacgctga tggcgatagc gcgagatcag cgctacgggc
    13141 agtaacgtca gtaaactacc gatcatcaat aacggaaaat gggttaaacc gaccgcctgc
    13201 gttagccagt aaatcagcag ccattccgca cccagcaata cgggccagta tccgcgcggg
    13261 cattgcagca ttagccctag ccgcagacca aacggaaata acagcaccgc catatcaggg
    13321 cgctcaacca ggtgcaggct gatactccac aggcaaaacc atgcggcaga gaagataaaa
    13381 aagcaggcaa taacggtaat taagcgggag aacaacgtct tcatcaccag ccatcaaaca
    13441 tgcggcgcgc cagttctacg tcgttactga cgcccagttt ttccatcaga ttggcgcgat
    13501 ggacgtgtac cgttttcggt gacaagccca gttcggcggc aatctctttc accgccattc
    13561 cttgcgccag tttttccgcc acctggcgtt cacgtttggt cagcgggtcc tgacgaccgg
    13621 atgccagttt aatggcaata tccggcgtca gataacagcc gcccgtagca accgtatgca
    13681 ccgccgcaat cagttcgtca gggctacagc gtttggagag aaagccgcgc gcccccgcgt
    13741 taagcgcctg ctcaaccagc gccggactgt catgaacaga gagcattatt gtcgccatac
    13801 ctttcggcag ctggcttagc agttccagac cggagatatc gggcatggag atatcgcaaa
    13861 tacacacctg cacaccgcgc cccggcagcc ccgccagcgc ctcgcgcccc gaaccaaact
    13921 cggcaactac ctgcaaatca ggttccagcc ccagcagctg cgcaaagccg gagcggacga
    13981 tgaggtgatc gtctataagg gcaacggtga tcatggtctt gtcctggcgg gtaaaaaaaa
    14041 acgcgcttac cttaacgata agcgcgatgt tgttcaagcc ttgagcggtt actgaaaaaa
    14101 caccgcaatc ttgttaaaca tagtcggatc ggactgatta cgctgcactt tcaccacatc
    14161 ttccagctta tcgatttggc ttatcatctg ctccagacgc tggtcgtcat tgaccagtag
    14221 ccagatatgg cttttgtcgc tgtcctgaat cggcagacaa agaatgcctt caacgttaaa
    14281 agcgcggcgg gcaaaaaggc cacaaacgtg ggtcattacg cccggatggt tgcgaacggt
    14341 gagctccaga atcacgttgt catgagttgt gttttgcatg gcttattccc ccaccatttc
    14401 agtattcgcc gcacctggcg gcaccatcgg gtaaactttt tcttcggcat caatgcgcac
    14461 atggatcagc gccgggccag ggcgattgat gatttcctgc aatgcagcct gcggatcggc
    14521 ttcgttattc aaatcacagg tttcgaggcc gaatccggcg gcaatctgca taaagttgat
    14581 ttttcccgga taggtggcgg caaaaacgcc ttgctcgtag aacagactct gttgctgatg
    14641 caccagcccc agcgcttcgt tgttcatcag aatgattttg acatccagct gattttcact
    14701 ggcggtcgcc atctcctgaa tattcatcat caggctgccg tcgccggaga aacacaacac
    14761 tttgcgatcc gggttcgcca gcgccgcgcc aatcgccgca ggcaggccaa aacccatcgt
    14821 gcccagccca ccggaggtca gccactggcg tgggcgattg agcggataag cttgcgcggt
    14881 ccacatctga tgctgaccca catcggtggt gataatcgca ttgtcatcga cacaggcggc
    14941 aacggcgttg atcaggccgt aatggcttaa tggatcgcac gctttcggga ttggacacgg
    15001 gaattcgcgc tgcaaatccg ctaccaactg gtgccactct gcacgcggtt gcgcttccac
    15061 ctgcgggatc aattgcgcca gcacgtcatc aacatccgcc tgaatcgcca catgcggctg
    15121 cttgatttta cccagctctg cgcgatcgat atcgacatga ataattttgg cattcggaca
    15181 gaactgctcg gttttgccaa tcgcccggtc atcaaaacgc gcaccgagca ctatcaacaa
    15241 atccgcctcc tgcaaaatat agttggtgct gcgcacgccg tgcatcccca gcatacccag
    15301 cgacaacgga tgcgcttttg gcaacatgcc cagcgccatt aaagtcatgg tggtaggcag
    15361 ttgcgctttc tccgccagtt cacgcacccg tgcgggcgca ttgatcacac cgccgcccag
    15421 ataaagcacc gggcgtttgg cagcgttaat catcgccgct gcgtcacgaa tgctttcttc
    15481 gctaaaggcg ggggcggcgg ctttttctgc catagcgggc tgtgtttcaa tctcaaaaac
    15541 tgccgtttgc acatccttag gaatgtctat ccacaccggg cctgggcggc ctgattgcgc
    15601 aatgcggaag gcatcgctca tgacctgcgg gagttcttcg atatgtctga ccagatagtt
    15661 gtgtttggtg atggggatag agatgccgta ggtgtccact tcctggaagg cgtcggtgcc
    15721 gatcatcgag gcgggaacct gaccggtgat gcaaatcagc gggatggagt ccagccgcgc
    15781 atcggcaatg gcggtcacca ggttagtcgc acccggtccg ctacaggcca tacagaccgc
    15841 cggtttaccg tcggtgcgcg ccatcccctg agcgataaat cccgcgccct gttcatgacg
    15901 ggccagaata tggcggattt gcgtgctttg gcttaaggca tcgtaaacag gcaggataga
    15961 accgcccgga atgcccgtca caatcttaat gccctgctgt tccaggaaat gaacgataaa
    16021 ttctgcgccg gtaaagcgct tacgcgtcga tgttgtgccc gaacttgcca tgctccagtc
    16081 cttttcttct gggccgactt tccgggaggt gcttaaacga aaaaccccgc ccggtttgcg
    16141 ccggcggggt tttggaatcg tgtgttgttc cagtccctac ggcgcattgc cgacgaccac
    16201 caccacacgc acgacgacca ctgcggcgga tagcgcagtt ggtagtagtt ttgcgttgaa
    16261 catggaagta gtcattgggg accttgttgg ttttgtgttt aacaatattt atacaagcac
    16321 agctttacag gggagacaat ggaaaatttt tcagcaaggg aaaattgagg ggctgatcac
    16381 gttttgtact gaattgcaga taacaaaaaa ccccgccgga gcgaggtttc atcagccgcc
    16441 tgcggctggt aaccgcaaag cacactgtat tatgtcaaca ctgaaagtat acgtgttccg
    16501 cgcagaacgc gcaatttcgg cacgaatttt gacgtattta gggcatagtt gagtatcgat
    16561 cacagtttgc gttttgtcca aatattactg tttatttata cagtaaactt ctataatatc
    16621 actgtacgca atgtgttatg cgggggccgc atcgttaccc ggcgcactaa gtcctggctg
    16681 aaacgggtgg tgccgtcagc gccttaaccc cgcgtgagca cactgtgtta tgtcaacaag
    16741 cacaacgttt ctccttaaga taccgcgtgc acaacagctg gcaacaggca gcggaaaggt
    16801 acgtcagctg gcagtgctcc tgaaccacag gagacgcgta tgagcctggt ggatatcgcc
    16861 attcttatcc tcaaactcat tgttgcagca ctgcaactgc ttgatgctgt tctgaaatac
    16921 ctgaagtaat tcagattcaa gtcgcaccaa aggggagcgg gtaaccgctc cccttttata
    16981 tttagcgtgc gggttggagt tgggggcttc ttctaccagc agaatgtttg cacctgcgct
    17041 gcctgtgccc ctcaccctag ccctctcccc aaaggggcga ggggaccgtc ccgtgcaatg
    17101 tttagctcat tttctgaaag ggaacggtgg tttccccctc gcccctttgg ggagagggtt
    17161 acagttcgca cgtaatccct cccggcaaca tttattgccg cttttgttta catattctgc
    17221 cgctaaacaa ttctccattc ctggcgtata tctggctaac attcatcaat gtgatagatt
    17281 cctctcccgc atttatggga atgcgtagtg acttattcta attattttta taaaagcatc
    17341 cgtgataatg aaaaggcaaa gaaacgtcaa tttgttattg atgttggtat tactcgtggc
    17401 cgtcggtcag atggcgcaaa ccatttatat tccagctatt gccgatatgg cgcgcgatct
    17461 caacgtccgt gaaggggcgg tgcagagcgt aatgggcgct tatctgctga cttacggtgt
    17521 ctcacagctg ttttatggcc cgatttccga ccgcgtgggc cgccgaccgg tgatcctcgt
    17581 cggaatgtcc atttttatgc tggcaacgct ggtcgcggtc acgacctcca gtttgacggt
    17641 gttgattgcc gccagcgcga tgcaggggat gggcaccggc gttggcggcg taatggcgcg
    17701 tactttgccg cgagatttat atgaacggac acagttgcgc catgctaaca gcctgttaaa
    17761 catggggatt ctcgtcagtc cgttgctcgc accgctaatc ggcggtctgc tggatacgat
    17821 gtggaactgg cgcgcctgtt atctcttttt gttggttctt tgtgctggtg tgaccttcag
    17881 tatggcccgc tggatgccgg aaacgcgtcc ggtcgatgca ccgcgcacgc gcctgcttac
    17941 cagttataaa acgcttttcg gtaacagcgg ttttaactgt tatttgctga tgctgattgg
    18001 cggtctggcc gggattgccg cctttgaagc ctgctccggc gtgctgatgg gcgcggtgtt
    18061 agggctgagc agtatgacgg tcagtatttt gtttattctg ccgattccgg cagcgttttt
    18121 tggcgcatgg tttgccggac gtcccaataa acgcttctcc acgttaatgt ggcagtcggt
    18181 tatctgctgc ctgctggctg gcttgctgat gtggatcccc gactggtttg gcgtgatgaa
    18241 tgtctggacg ctgctcgttc ccgccgcgct gttctttttc ggtgccggga tgctgtttcc
    18301 gctggcgacc agcggcgcga tggagccgtt ccccttcctg gcgggcacgg ctggcgcgct
    18361 ggtcggcggt ctgcaaaaca ttggttccgg cgtgctggcg tcgctctctg cgatgttgcc
    18421 gcaaaccggt cagggcagcc tggggttgtt gatgacctta atgggattgt tgatcgtgct
    18481 gtgctggctg ccgctggcga cgcggatgtc gcatcagggg cagcccgttt aagcgcacgt
    18541 caccgcagca tcgtcatcag ctccatggga gaacgatgct gctttatcag atcacgcatc
    18601 acccgcatat gcggtgcgga gtaagaataa aacgcctgat agcccgcaca aagcacgctg
    18661 tctggcgtct cctggcgagc gtgcgggcac aggcgatgcc agtcgcacgc ctggcagtca
    18721 cggcgcggtt gcgggttttc gctgccacac catttttgta aggtggcgtc aaaaagctca
    18781 atcgagatac gactgatatc tgcccgcacc caacactcga acagggcaat taaaaatttc
    18841 ccccacagct ctgctgtcac cgaagcggcc gtcagatcgc cccggtcatc aaattcaaga
    18901 tagggaatga gctgtacgga gcggatgccc cgctgtttga aattgtgata aaaatcggca
    18961 ggttgcagag catccttgta ctctacaacc agtttatgcc tgtcctcttc agcatcaatg
    19021 acctgacttc ctgtcatgcg actctctcaa taaatacgat aagttgatgt atatgcgtta
    19081 cagcaaacag tattgcgaga gataacaccg cgagggagat caaaaatttg tcacggacta
    19141 cgtgaaattg ggaaaaatcg ctattcgtga catccattaa attgcgatta cgggtgtagt
    19201 gccagaggat cagcgccacg atggcgagaa tgccaatcga aatccagaat aacatgcccg
    19261 cctggtgcca gttgtgtttg atagccaacg ccatcaacgc gccgtagccc agcatggtac
    19321 gaaaccacgc cagtgatgtg cgctccggct gcagtcctgg gtcggcaatg cgtctggctt
    19381 tgcggctatc cggcatacaa caccagtccc ataacgatca ccgccacgac catcaatatt
    19441 aagctaatga ttaataagct gttggtgtag ggcaggtcct ctttcagacg catcgctttt
    19501 tcattgcgta accagcgcag gtagccatac atcgctaacc caccggaaaa tagacacaac
    19561 aacaacgcca gcagttcgcg aatgacgggc gtggcgaaat ctggcgcaag ttggtcaagc
    19621 ccaacccccg ccgccagaaa tcctagtgcg gtacggatcc acgccagaaa agtacgctca
    19681 ttagccagcg agaagcggta atcgggcgct tctccgaggc gggaaatttt cattgttgct
    19741 cctttgcaat ttcactaacg ctctatcttt agcggttttt tttaagaatt tcgtccgccc
    19801 gtttcctgat atgcttttgc catcccctac aaggaggtca gatgggtatc atagcgcaaa
    19861 ataaaatcag ttcattgggc atgctgttcg gtgccatcgc tttaatgatg gggattatcc
    19921 acttttcatt cggccctttt tccgcaccac cgccaacgct tgaaagcatc gtggcggaca
    19981 aaacggctga aattaaaaga ggtcttctcg ccggaataaa aggcgaaaaa attactaccg
    20041 tggagaaaaa agaggacgta gatgtcgata aaatcctcga tcaaagcggt atcgcactgg
    20101 ccattgctgc gctactttgc gcatttattg gcggtatgcg taaggaaaat cgctggggca
    20161 ttcgcggcgc gctggttttt ggcggcggga cgctggcttt ccataccttg ctttttggta
    20221 tcggcatcgt gtgcagcatt ttgctgatat tccttatctt ttccttcctg actggcggtt
    20281 cactggttta agcagcctga ataatgctcg ccgggtgttc atcagcgggc attatcgtca
    20341 gaacttctgt tttttctctt ccactttcac tccttgcgtc ggtaggccgg tgtcatagtc
    20401 acgtaccacc ggcgaatagc catcttgtgg gcgtggacga aatgccccca tccagcgcgg
    20461 cagtgcatct ttacgccacg gacgcaggct ccattggtaa ctgcggaacg gatcgcgaat
    20521 tttgtccatg taatccaata aggcgtcatg cattttgctg cgaacgtctg caaaacggat
    20581 atcatcgatc aggttatgca tttcatttgg gtcattacgg cgatcgtaaa gttcatcact
    20641 ggtgaagagg ttgagtacca gtttaaagtc atccgtcacc cagcaacgca ccggaataaa
    20701 accgccaaag ctgtcatgct caatctcgta gcggttaaat tccaccatta caccgcgtgg
    20761 ctctttcacg gcaaggatat tttcccccgg cagaatctct ggtttttcaa tatctgccag
    20821 cgccatcatt gtcggcagta aatcgatatg actgactggc gtatcgacct gtcgccgctc
    20881 cccttgcggc gaacggatga tcagcggaat acgggtgatg tcgtcataca tcgccgctcc
    20941 tttactgatc agcttatgtg cgcccatcat ttcgccgtga tcggaagtat aaatgaccca
    21001 cgtattttca cgttgctctg gcgttaaggc attgatgacc cgtccgattt ggtcatcaac
    21061 aaagtcatta caggcaaaat agagcggatg gtgataaagc ccgtcatcac cgactggcga
    21121 tggcatcgcc tgcgcccata agcggtgatg ttccggtttg ttcgccaggt catcctgagc
    21181 tttctcgccc agatcgtagt aaaaatcagc gtatttctct aaatactcca ccggacaggt
    21241 gaacgggtga tgcggctcat catacgaaac caccatcagg aagggttcct cggcgcgcgc
    21301 gggctgttgc agaaaatcta ccgcccgatt gctgatgcgg tgcgcccagg tgaaggtttc
    21361 gtcgatatgg ttcgcctgta aatcctcaac gctgtttagg ccattgcgcc acaggctgat
    21421 ctctttttcc gtcagttcgc taaggtagtt cgccccatcg aaccagtaat cagcgtccca
    21481 ctccggcgga cactcgccag tgccgaaata gtcatgaccg tcgagatgcc atttgccgat
    21541 gtaacaggtg tgatagccgg catccttaaa gtagcgcccc atagtggaga tgtttttgcc
    21601 tggcgcgacg ttgttggtcc acgggccgga ctggttagcg tagataccgg taaatagtcc
    21661 ggcgcgtgca ggcgtacaaa ccggtgaaca ggtgtaggcg gaattaaagc gaataccttc
    21721 cgccgccaga ctatcaatat tttgcgtatt cagcggttta ccgctatagc aaccgaccat
    21781 attggtggcc tgggtatcgg tcatgatgaa cagaaaattg gggcgtttca taggctatcc
    21841 ttcgcgtcgg gagtaaaggt tacggctggg tcgtgacgat gccgccagct gtcaaaaatc
    21901 aggtagacaa tcactacggc ggcaatgaaa taactgatca tcgataacca gcgcgtaccg
    21961 tagccgccga attcagccag cccggcatag acgccaatca tcgcgaacag gatgccaatt
    22021 gacgcgatct tgacgtttct ccacggtttc atgtccaccg caaacgcatc tttgaaggtg
    22081 aacggcgtgg agcgcggttt gataaaaccg atcaccagca tcacgaccac gttgatgcag
    22141 aacgtacagg ccagcacata gaggaaatgg aagtcgaact tcaccagata gttgatggtg
    22201 atgtagctga ttatgccaat ccccatcgcc acttttgccg ccagcgccgg gatgcgcggg
    22261 aagaaaaagc ccataatgat gatggtaacc agcggcacgt tgtaaatgcc gttgagctgt
    22321 ttcatccagc tatacagccc ctgcggcgcg ttggcgatcc acggcgcgac cagcaccgaa
    22381 acgatagcga taaagaaacc aaatttgcgc ccgacggtga ccagctgctg cggctcggca
    22441 ttctggttaa tgatgcgacg gtaaataccc atactgaata acgtactggc gctattcaga
    22501 aagccgttga aggtactgat caccgcacca aataacaccg cgccgaagaa acccaccatt
    22561 ggcactggca gaacgttatt gaccagcgtc gggtaggcca tgtcggcttt cggtaaatcc
    22621 tgatacagat gaaacgcaat caaccctggc agcaccagta ccagcgggtc gagcattttc
    22681 agcaccgccg ttaacagcgc ccccttttgc ccttccgcca ggctttttga cgccagcgtg
    22741 cgttgcacga tgccctgatt tgtacaccag taaaaggtgt tcaccagaat caaaccggta
    22801 aatgccgcgc caatcggcaa gggatcggtc gggccaccga ttgagtttaa tttctcggcg
    22861 tgaacggtgg tgagttgctc aatgccctgc ataaagctgc ccttgcccat cgcgatcagg
    22921 ccaaataccg gcaccatcaa cccgccgata accagcccaa taccgttgat ggagtccgcc
    22981 actgccattg cgcgcagtcc gccgatcacc gcatacaaaa ttcccgccag accaagcaaa
    23041 attaccagta gccagatagc cgcaccgtga gaaatctgta gcgattcccc gacgtgaaac
    23101 aggctgttga gcgccaacgc gccggagtag agaacaatcg gcagaaagca gacgccggtg
    23161 gcaatgagga agcagaagtc gatgataata cgcgtcgttt tatcataacg ttcctccaga
    23221 aaatcgggga tggtggcaat gccgcgcttc agatagcgcg gtaaaaagat tagcgcgagg
    23281 aagatcagcg tcaccgctga agtcacttcc cagcccatca ccgacatgcc gcttttgtag
    23341 gcctgcccgg aaaggccgac cagttgttcc gtggaaaggt tggttagcat taacgaagcg
    23401 gcaataaccg gcgcttttag tgaacgtccg gcaagaaaat agccttgttg cgatccggta
    23461 tctattttgc ggaccttcca ccaggtgatc accgccacca gcagcgtaaa accgacaaaa
    23521 ctcaagattt gtaacgaatt catctcatag cccttattta tgtttatgtc ccggacgcat
    23581 gaatataggg agaggtaaaa tgcgtcgggt caggcagtca gattcttaaa atacaaacgt
    23641 cgtatccctg aacggattgt tttctgttaa gttcaggttg tgagcataat tcgccggagg
    23701 gatattaaaa tgaatggaaa attgcaaagt tcagatgtaa aaaacgaaac tccgtacaat
    23761 attcccttat tgattaacga aaatgtgatc tccagcggaa tttctctgat ctcgctctgg
    23821 catacctacg ccgacgagca ttaccgggtg atctggccgc gggacaagaa gaaaccgctt
    23881 atcgccaact catgggttgc ggtgtatacc gtacaaggat gtgggaaaat tcttttaaag
    23941 aatggcgaac aaataacact gcatggcaac tgtattatat tcttaaagcc aatggatatt
    24001 cactcttatc actgtgaagg tttagtctgg gaacagtact ggatggaatt tacccccacc
    24061 agtatgatgg atattcccgt tggtcagcaa agcgttattt ataatggcga aatttataat
    24121 caggaactca ccgaagttgc tgagttaata acttcaccag aagcaataaa aaataatctg
    24181 gcagtcgctt ttctgacgaa aattatttat cagtggattt gtcttatgta cgcagatggt
    24241 aaaaaagatc cacaacggcg gcaaattgaa aaattaattg ccactttaca tgccagtctg
    24301 caacaacgct ggagcgtagc tgatatggct gccacgatcc cctgtagcga agcctggttg
    24361 cgtcgtctgt ttttacgcta taccggcaag acgccgaaag aatattacct cgatgcgcgt
    24421 ctggatctgg cgctatcgct attaaagcaa caaggaaact cggttggcga agtcgctgat
    24481 acgctcaact tcttcgactc ctttcatttc agcaaagcct ttaaacataa atttggttat
    24541 gcgccgtcag ccgtgctaaa gaatacggac cagcacccaa cggatgccag tccacacaat
    24601 taacgtaact ctggccagta cgctttgttg gcctccagca actcatccag aatagctttg
    24661 gcgaccgagg cgctcggtac cgttttcgac aacgtaatcg cctaccacag gtgctgatat
    24721 gaacgctgtt cccaggcgtc cacgaccagt ttttccaccg ccacttgctg actcattaac
    24781 cctttctgaa actgcgggat atcgccgacc accagtggtt caggccgtag tagcgcacgc
    24841 gcatctgttt gcgatcttgc agcccaacaa tttgcgccat ccggctttca ataccgattg
    24901 gcatgtcaca gatgttgagg attttcgcat tcgggcgcag acgacgcgtg gcttctgcga
    24961 caattgctgc cgggttggag tagttgagca tccaggcgtt tggtgaatat ttttccatat
    25021 aatccaccag ttccaggacg ccgccaatgg aacgcatgcc gtacgctatt ccgccgggtc
    25081 cgcaagtttc ctgaccaaca acaccgtggc gcagtgggat tttttcatcc agttcgcgca
    25141 tcgggtactt gccgacgcgg atgtgcgcca tgacaaaatc aacgtcgctg aatgccactt
    25201 caggatcggt ggtgtaacta aacgcaatgt ccggcgcttt ctctttaagg atgactttac
    25261 aggcttcggc aatcacttcc tgccgcgcac catcgttatc ataaaatttc agtgcacgaa
    25321 gcgggaaacg gtcctgattc gccaggagca tcaacacgat gcctggcgta aaggtgcttc
    25381 caccgcctgc gacaaccact gagaatttgg tcattatact gcctccgtaa tggcaacatt
    25441 ttctgctgat tgatgagaat taattaagct atcgagctgt tcacgcagct gggatacatg
    25501 cagaccaatg atcacctgaa tggcatcgcc actacggaag acgccgtgcg ctcccagctt
    25561 tttaaagact tcgtcatcca gcgtttgtga catgtcatgc agtgcaatac gtaaacgcgt
    25621 cgcgcaattg ttaatgctgg agatattgcc gaccccgccc agggcttgca ggataccggc
    25681 agcctgatcc agctcttttt ttggctctgc cgcggtggtt tggcctcgcg aggctttgta
    25741 ttcggctttt gagtagagtt tcacttccgc atcttcacgt cccggcgtgc acatgttgaa
    25801 ctgcagaatc agtgtgcgga aaaccacgaa gtacagcagg gtaaagcaca acccaatggc
    25861 gatttgggtc agcatcatat ccgcgtggtt gctgaacatc gggatccagt tttgcggtaa
    25921 aacctggtca atcagacctc cgcccatgtt gcccaccaca ccaaagagat acattacggt
    25981 cgacattgag gccgccagca cggcgtgtac cgcaaacagc aacggtgaaa tgaacaggaa
    26041 ggtaaattcc agcggttcgg taattcccac cagcatggcg gttaaggttg cgggaatcag
    26101 caagcccgcc acttttaccc gattttccgg tgcggcagtg aagtacatcg ctaaagaaat
    26161 gcccacggca ccaaagattt ttgagttacc gtgcagggca aaaccgcctt ccgggaacaa
    26221 cgatttcagc ggctcggcgc tcaaactgaa ctcttgcaga tgctgcgccc agtacatctg
    26281 aatgccgcct tcaacagctg ccggaccaaa gataaactgt ccgtagatga agtggtgtaa
    26341 accggttggg atcagaatac gttcgaggaa ggtgtaaacc cagaccccaa gtgcacccgc
    26401 cgaacgcagg aacgcttgca gagattcaat ccccatttgt acttttggcc agccgagcaa
    26461 cgtcagccag gcacagggga tcatcaccag gaaggcgata atcaccacat aagacgtccc
    26521 ctggaaaatg ccgagaaaaa ccggcagttt tttatcgaac agacggttat gcagcgccgt
    26581 cacaatgccg gaaatgataa ttgcgccgat aatgctggta tcgagggttt taatcccagc
    26641 catcattgtc agaccgctac ctgccaccgc gtcctgagtg aaatcgacgc cgaagtagct
    26701 tccccaggtc attcccatcg cattgatgaa atagttccag gtcaggaaac tcaccatcac
    26761 cgccagacaa gcacgtccct gcgcttgctt agcaaggcca atgggtaaac cgacagcaaa
    26821 aatcagcggc atattacgga ataccgtcca accgccctct tcaataatgt gtacgatttg
    26881 cgcgaataaa ctgttcggat cggtcagtga ttccccgaca aacatcgggt tttgcagcaa
    26941 gatggcaaga cccaccacaa tcccggcgaa gggaaacagc agcactggcg tgaacatcgc
    27001 gccgccaaag cgttgaattt gactgagcat ttccacatcc tcttttctca attctgtaag
    27061 taggaagcct gattggttat gcggcaggcc tggagcgagg ataggaagat gcgatcggca
    27121 gaacatgacg acccaatggg attcgtgatc gctttcatgc ttttcgttgg gcggtagaga
    27181 tctacgtttt cgcgaaaaag tagacatctg tgagcactgg tacacagcat cgaacacatc
    27241 tttaaaaaaa agatgttttt tcaatcgatt aagcagaact tgtgggcgca ttacccgggc
    27301 ttgcaggcaa aaaagagatc tagagatgat ctacaaaagc attgcggagc ggttaagaat
    27361 tcgacttaat tacgcggatt tcacgctaaa cagccttctt cccggtgaaa aaaagttggc
    27421 ggaagaattt gcagtatccc ggatgaccat ccgtaaagcg attgacctgc tggtagcgtg
    27481 ggggctggtg gtccgccgcc acggcagcgg cacttacctg gtgcgcaaag atgtgctgca
    27541 tcaaaccgcc agcctgaccg gactggtgga ggtgttaaaa cggcagggaa aaacggtcac
    27601 cagccaggtg ctgatttttg aaatcatgcc tgcgcctccg gccattgcca gccagttacg
    27661 gattcaaatc aacgagcaga tctacttctc ccgtcgcgtt cgttttgtgg aagggaaacc
    27721 gctgatgctg gaagacagct atatgccggt taaactgttc cgtaatcttt cgctgcaaca
    27781 tctggaaggg tcgaagtttg aatatattgg acaagagtgc gggattttga ttggcggtaa
    27841 ttatgaaagc ctgacgccgg tgctcgccga tagactgctg gcgcggcaaa tgaaggtagc
    27901 ggaacacacg ccactgctgc ggatcacctc gttgtcatat agcgagagcg gggagttttt
    27961 gaattattca gtgatgttca gaaatgccag cgaataccag gtggagtacc atttacggcg
    28021 actccacccg gaaaagagtt aaccgatact ccagaagagc accgccagta attggggggt
    28081 gataatgcgc agaaacatca ctaacggata gacagtggcg taagagagcg ccgccgcacc
    28141 actggttgga tgaagattat tagcaaacgc cagcgccgga ggatcggtca tggaacctgc
    28201 cagcatcccg cacatggtca ggtaattcat tttggctaac atccgcgcca gaatgccaac
    28261 agtaatcagc ggaacggcgg tgatcagggc accataacca atccagctta gcccttcgcc
    28321 attgaccagg gtattcacaa aatccccacc agatttcaga ccaacgaccg agaggaacag
    28381 cacgatcccc agctcccgca gcgcgaggtt ggcacttggc ggcataaacc agtacagctt
    28441 gccgatactg ccgatacgcc cgaggatcaa cgccataatc agcggaccgc ccgccagccc
    28501 cagtttcaac gcggccggga acccaggcac aaagacggga atagaaccta acaatacgcc
    28561 aagcccgatg ccaataaaca ctggcagcat ctgaacctgt tgcagttttt gctgcgcatt
    28621 ccccagcaca ttggcaacgg catcaattgc ggacggacgc cccaccagat tgaggatatc
    28681 gccgaactgc aggctgatat cgccactggc gaccagttcg accccggcac ggttcaggcg
    28741 cgagataaca acgtcatagc gttctttaaa gtgcaggtcg cgaatacgtt ttccgagcac
    28801 gttttcattg gtgaccacca cacgctcgac gcgcaaatca gtgcctttcg tggacagcga
    28861 agtatcgacc tcctgaccaa tcaccagttg cgcattatgt aaatccgctg gctgacccac
    28921 cagatgcagc aaatcgccca gttgaataat ggtatctggc gaaggaactt ttagggtttc
    28981 ttcgcgtttc agacgcgagc agataatttt gtcgccgttg agaatcggta catctttaat
    29041 ggctaaatca tgcaggttag ggttctcaac gcgaatattg atagtcttga tcagcgcgcc
    29101 gccattggtg cgtgaagact cgtgctgctg agcttctgtc tcgacattga cgcggaaaat
    29161 aacccgcaac atccacatgg tgaacaaaat cccgcaaatg ccgaatggat acgccatcgc
    29221 gtaactcatc cccatctgat cgaccatttc cattggtgta cccaggtcgc gcaaaatctg
    29281 ctgccctgcc cccagcgctg gcgtattggt aaccgcaccg gagaaaatcc ccagcactac
    29341 cggcagtgga atatcaaaca gtttatgcag gatggcggta accagaccac cgatgatgac
    29401 gatcagaaca gcaaacaggt tgaggcgtaa tccggagacg cgcaatgagg caaagaagcc
    29461 cggccctacc tgaatcccga tagtataaac gaacaggatc aggccaaatt cctgaataac
    29521 atgcagcata tcgctactta atgtcatccc cgcctgagaa acaaaatggc cgacgatgat
    29581 cccaccaaac agcacgccgc caatacctaa tcctatgccg cgaaatttga cattgccgat
    29641 aaacaaaccg acgactgcca ccaaagccag aatactgacc gttaatgcta tatcactcat
    29701 cgtccatttc tcttgagata acatttttaa ttgctacgga ttatggctga atcggtgaag
    29761 cagatttgcc ttatagcgca cattatcacg ggaaagaacg tgccgaaata tcttaaacag
    29821 tcgaaattta acgcattgtt gagtaagtaa gacaaaaaaa gccccaccag aatggcgggg
    29881 caaagagaat agctagttag ctatttaacg cgggacgttc gctgatagcg atacgctgcg
    29941 ctgcgatggg ttcaggctca ttacgaatta aatcaatatg cagtaaaccg tttacgaagg
    30001 ttgcgccaga gacttccata ttttcagcca gcgtaaagct caggctaaat ggctgattca
    30061 taagcccttg atgcagccat tttttctctt cttttggctg ctccggcgtg ccttttacgc
    30121 tcaggcgcgt accttccagt tgaatctcta aatcttcctg acggaaacct gccagcgcaa
    30181 gggtaatgcg gtagtggtta tcgtcgcttt tctcaatgtt gtacggcggg aagctctggc
    30241 tttcaccggc gttttgcagt gcgttggcca gtttgtcaaa accgatccat tgacgcatca
    30301 gtggggataa atcgaagtta cgcatagtca tttctccttc taagaagcga gtaagtacct
    30361 gcaaatccga agattcgcat atgctccctg acggcgagca tggagatgtc aggccgcgcc
    30421 aggcggcctt agggaattag ttgatttcga tacggcgcgg ttttttcgct tccggaatca
    30481 cgcgttcgag atcgatatac agcaaaccat ttaccaggtt agcaccacga acatgaatgt
    30541 tctcagctaa ctggaatttg cgttcaaagt tgcgttcagc gatgccctgg tacagatagg
    30601 tgcgctcttt ttgttcgtcg gcgtgagcac ctttcaccac cagcagatta tcctgggcgg
    30661 taatttccag ttcgctctca gcaaaaccag ccacagcgat agcaatgcgg taatggtttt
    30721 cgtctaccag ttcaacgtta tacggagggt agccgccatt actctggctc tggttgtttt
    30781 ctaagtggtt aaacaaacgg tcaaatccaa tagcagaacg gtaaagcggg gataaatcaa
    30841 agttacgcat aatcaatagc tcctgaaatc agcgagaatg taagaccttc cacaatggac
    30901 aggtcaggta gccagaacac ccatcaggcg cgtcctcatc ggctacgatg taaaaatggg
    30961 tctggaaatg aacttttcaa gccttatcag cggacttttt tttgcagttt atggtctatt
    31021 gcatagactg agggggcagc acgaaacgtt aaagtgcgat agccgccaca gtgcgacgta
    31081 atgatgatgt tattttcagc aagggatcgc tataactcat caggccaaca cccacgatca
    31141 acagatgaat ttattatgat aagaaatgtg ttgttagcgt tcatgatatg cagcggaatg
    31201 acattactcg gaggatgctc cagcgtgatg tcccataccg gagggaaaga aggaacgtat
    31261 cccggcaccc gcgccagcgc aaccatgatt ggcgacgatg aaaccaactg gggcactaag
    31321 tcgctggcga ttctcgatat gccgtttacc gctgtgatgg acacgctttt actgccgtgg
    31381 gatgtgttcc gcaaagacag ttcggtgcgc tcacgcgttg aaaaaagcga agccaacgcg
    31441 caagccacca atgcggttat tccaccggcc agaatgcctg ataactgatt tagcgatcag
    31501 tttcggtgat ccacagctgg ccaccttcca tccacgccag ccattgacca tccggcgaga
    31561 agaccacggc gtccgcagaa ggtggattgg cgtggttttc ggttaaatac tcaacctcgc
    31621 cgctttgcgc atgggcacaa gcaattcgat tatccagcac aaagcccaac cattctcctg
    31681 acggatgcca gttaaatgca gactgaatat ccgttttgtt atgggttaac tggcgcggct
    31741 cgccgccctg tggcgagata agccacagtt gcacaatgcc gttatcatca cgcattaaaa
    31801 acgcgatttg cgtaccctgc ggattacagc gcacccagtg gcgcgggacg ttgactaacc
    31861 ccggataagc ccgatggtgg gtaaaggtta aacgtcgctg cacgacgccg cgcggtggcg
    31921 cgggcagggt ggtttccgtt ccacttaacg gcgcatcacc tgccgctttc cagccagctt
    31981 catcttgcgg taactcaacg ataaacagct ccggcacttt ctcgcccttt ggcgaaagtg
    32041 tgtcgccaat aaacgccagc gcgtgatttc ctacccatcc ttcttcataa gcacgattga
    32101 tttcatcgct gccaggctgc ggcgtgggcg tggttttact caccagcacg caccagtggc
    32161 taccgctgta ttcacgcgga tgctgctttt gtacgttgac cgggccaaac ggcgcagcaa
    32221 caccgacgtt tcgcaaatcc agcgccggat cgagttcatg cattacatgg tcgttatagg
    32281 taaagctcac cctttcaccg ttcgggctaa agacatgcac atggctgccg ccgcgcagcg
    32341 ctcctggcgt atacggcgcg gtaatatcca ttgcatcgag attgctcacc ttgccgcctt
    32401 cagcaatgac tccgcgtcga tgatggaaat cgtaatgcca tgtttcatca ggattttccg
    32461 ggccatggat gaaaacatat ttctctgact tcggatgaac ggtcaccacg ccgacgtgtg
    32521 cgccctgtga cgcgcgatag ataacctcga cctcgccggt atggatattc acacgctcaa
    32581 tggtctcgcc ggtaaacgac gccccagaag gacgcacgtc aaataccagc cactggctgt
    32641 cgggcgtcca ggtattggta ttggtgagca ggtgattacg gggagcaaag gttatctgtt
    32701 tcatggcgcg gtcctgatac aaaacgggtc ccaccatcat acttcacaag gacttcactt
    32761 tcagacaata gtcttttgcc atcgtgatga atgtgagtga aaagatggaa catttcgacg
    32821 tggcgattat tggcctcggc ccggcaggat cggcgttggc gcgaaaatta gcaggcaaaa
    32881 tgcaggtgat cgcgctggat aaaaagcacc agtgtggtac tgaaggtttc agcaaacctt
    32941 gcggcggtct gctggcaccg gacgcgcagc gatcttttat tcgcgatgga ctgacgcttc
    33001 ctgtcgatgt gatcgccaat ccacagattt tcagcgtcaa aactgtcgac gtcgccgcat
    33061 cgctcacgcg taactaccag cgaagctata tcaatattaa tcgccatgct ttcgacttgt
    33121 ggatgaaatc gctgatcccc accagcgttg aggtttatca cgatagcctg tgccgaaaaa
    33181 tctggcgtga ggatgataaa tggcatgtca tttttcgtgc agacggctgg gagcaacata
    33241 ttaccgcccg ctatctggtc ggtgccgatg gcgcaaactc gatggtgcgg cgacatctct
    33301 acccggatca tcaaatccgt aaatatgtcg ctatccagca gtggttcgcg gagaaacatc
    33361 cggtgccgtt ctactcctgc atctttgata attcgataac taactgttat tcatggagta
    33421 tcagcaaaga cggttatttt atctttggcg gtgcttatcc aatgaaagac ggtcagacgc
    33481 gtttcacgac gctgaaagag aaaatgagcg cctttcagtt ccagtttggt aaggcggtga
    33541 aaagcgaaaa atgcacggtg ctgtttccct cacgctggca ggattttgtc tgcggtaagg
    33601 acaacgcctt tctgattggc gaagcggcag gatttatcag cgccagttcg ctggagggga
    33661 ttagctatgc gctggatagc gcagacattc tgcgtgcggt gttactgaag cagccagaga
    33721 agctcaatac cgcttactgg cgcgccaccc gcaaactgcg tttaaaactc ttcggcaaga
    33781 tagtaaaaag ccgatgcctg accgcaccgg ctttaagaaa gtggattatg cgcagtggta
    33841 tggcgcatat tccacagttg aaagattagc caacgcgctt cacatcgccc accagcagga
    33901 tgtaagagag cgcgccaatc aacgcgacgg cggagatata aaccagtgca ggtgcgaaac
    33961 cgtaaccctg cgccaggtac cccaccacca gcggaacggt gatgccgccc agaccaccgg
    34021 cgaagttaaa cacgccgccg gttaaaccaa tcaggcgcat cggtgccaga gaagagacca
    34081 gcgaccaggt aatcgaagca aaaccgttgc cgaagaatgc cagcgccatc aggcacataa
    34141 tcatcatcgg atcgttggtg tagttagcgc ccataatgca ggtggagatc agcaagccgc
    34201 agataatcgg cgttttacgc gcaaagccca gtgaaaagcc cttacgtacc agcagatccg
    34261 cgacccagcc agagagcagg acgccgacaa acgccgcgag gaatggcacc gtggtcataa
    34321 agcctgcttt cagcgccgtg attccttttt cctgggttaa atagttcggg aaccaggtta
    34381 agaaaaacca cagtgtagaa gccaccgcaa attgcccaag ataaacgccg atcagtttac
    34441 gatggaacac cagtttccag tctttggctg ttaacggctg acgcgcctct ttcttcaccg
    34501 gcgcatcacc atccaccaga ccgccgccat cacgaatgta atccagttca gctttgctga
    34561 tacctttggt caggcgcggc ggctgataaa ccttaaacca aatcagcgac cagataatgc
    34621 cgataccacc agtgacaatg aacacccagt gccagctcaa catctcctga atccagatca
    34681 gcagcggagt caaaaacgcc agaccgacaa actgaccaga cgtataaaaa ccaacggcgg
    34741 aagcgcgttc atgttccggg aaccagctgg tcaccatccg gttattggtc gggaaagcgg
    34801 gcgcttcgaa aataccggtt atcgcacgca gaccaattaa tgacattaat cccgtggcaa
    34861 agccctggaa taaagtcgcc actgaccaac caaatatcgc aataaaataa gtcacgcgat
    34921 ctaaaaacca accgccgggg atctggcata gcgtataaag ccaggcgaag gccgaaaata
    34981 catagcccat ttgcgctttg gtaataccga actcttcctg aatatgggcg gaagccacgg
    35041 ccaggttagc gcggtcaaca taacaaatga ccaccgtaat aaagatcatc accagcgtca
    35101 gataacgccg acgccccggt tttgctgcat taacgggaat atccatagcg agcttcctcc
    35161 agattttggg catagcgaag ccgctcacca tgccctgtaa tttacagagg gttatatttt
    35221 tgtattgctg ttttagtgcc cgatgagggg cttacgtggc aggaattacc actctgctac
    35281 gctgttatct tcatgacgcc agagcggatt acgccagtcc ggggcatttt tactgaactc
    35341 aataacttta gcttcgtcga tttccacgcc taagcccggt ttcgttagcg gtttaaagaa
    35401 gccgccaacc atgctgaagt cttctttgtt tttcacaaag tcgagtaact ccgcgccttt
    35461 gttgtaatga atgcccatac tttgttcctg aagtacggcg ttataggaaa caaagtcgat
    35521 atgcaggcaa gccgccagtg caatcggtcc gagcggacag tgcggcgcaa gggtcacatc
    35581 ataggcttct gccattccgg caattttgta gcattcggta ataccgcctg catgggagag
    35641 gtccggttgc agaatcgaaa taccacctgc ctccagcacg cgtttaaaat cgaaacgtga
    35701 gaacatgcgc tcacccgccg ccagtggaat atgcgtttgt gccgccagtt tcgggtagta
    35761 ttcggcttgt tccgccagca ccggctcttc aataaacagc gggcgatacg gctccagttc
    35821 tttaatcagc actttcgcca ttggcgcgct gacgcgaccg tggaaatcaa gaccaaactc
    35881 aatctgattg ccaaaagctt cacgaatttg tgccacggtg ttgactgccg catctaccgc
    35941 gcgggagtta tcaattagcc ccagttcttc acaaccgttc agtttaaagg tatcgaagcc
    36001 gatttcgcgc agggttttaa tgccgtcgat aacatccgcc ggacgatcgc cgccgaccca
    36061 actgtaggct ttaattttgt cgcgaaccag gccgcccatc agttgccaga ccggcgcatt
    36121 cagcacttta cctttgatat cccataacgc ctggtcgatc ccggcgatgg cgctcatcag
    36181 gattggaccg ccacgataaa atccggcgcg atacatcact tgccataagt cattgatgcg
    36241 cgatggatcc tgaccaatca aatagtcacc cagctcgtga actgccgctt ccaccgtgcg
    36301 ggcgcggcct tcaatcacgg gctcgcccca accgaccacg ccttcatcgg tttcaatttt
    36361 caggaacatc cagcggggag gtaaacgata cgtggtaatt ttggtgattt tcattgcact
    36421 gcctctcgat acgccttaac aaatgctgct gcctgctgcg cggtgcgttc tacggactgc
    36481 ccggcgcgat agagatcgct gcctaagccc gccccagcac aacctgcgtc tatccactgc
    36541 gccaggtttt ctggcgtcac gccgccaacg gcaaagactg cgatgtccga tggcaatacc
    36601 gcttttaacg ctttgatgta ttgcggacca aaagccgatg acggaaatat tttcagcgcc
    36661 tgcgcgcccg cttcgagcgc ggtaaaggct tcggtcgccg tcgcgcagcc ggggcagacg
    36721 gtcatgccgt agcccaccgc acggcggatc acttcactat ggatattggg cgtaacgatg
    36781 agctgacagc ccatcctggc gagcgcatcg acctgttcag gtttcagtac cgtacctgcg
    36841 ccaatcaacg ccttgtcgcc atacgcatca acgatggcgg gaatgctttg ctcccattgt
    36901 ggggaattca gcgggatttc aaccgcgtcg aacccggcgt caatcaccgc gccaacatgc
    36961 gccagcgcct cgtcgggctt aatgccgcgc aaaatggcga tcagcggaag tttagtttgc
    37021 cactgcatga gcgatgctcc ttataccagc ctgaaatgcc gtgtcgcccg ccaccgccgt
    37081 cacgtcgcaa cccatcgcct gaaaggcttg ctggtagcgc gcggtcagcg atgttccggc
    37141 gacaagggtg atggcgtgtt gatgggtcac atagtcgcgc atactggcaa cctctgcgcc
    37201 aatcaacaaa ccagagagaa attcgctgac ctgttcgcgg ggaagtgttc ccagcacatg
    37261 cgaggcgcga acttcaaaaa gctgcggcaa tatggcgggc gcattaaggc cgcgctcaag
    37321 gccagccgcg aaggcatcgg cagagttttc ctgcggcggc aaacctgcgc caatcaatga
    37381 gtgatttaac agtaaatgat gtaattcacc ggtcatcacg gtgcgaaaat cgttgatttg
    37441 ctggctatcg gcctgcaccc atttgcaatg cgtaccgggc ataacataaa gagaggaagg
    37501 agccagagct cgcgcgccga tcaattgtgt ttcttcgccg cgcatcacat tgtggttatc
    37561 gtcatgagag acgcataatc cgggaataat ccagatattg tcgccaacag acgttaattg
    37621 ttcgccaata gacgaaaaac gggcaggaac agataaatac ggagcaactt tccagccgac
    37681 attgctgccg accattcctg ccatcaccac tggcgtattt tcttcacgcc agtcggtcgt
    37741 gacttctgct aacaccgcag ccggagattt tccgttcagg cgcgtgacgc ctgcttctga
    37801 ttgcctgctc tccaggcagt ggtcgccctg ataaagccag gcgcgcagat tggtcgatcc
    37861 ccagtcaatt gcgatgtagc gagctgtcat gtgatttcct ttaaccttcg tgtcgagctg
    37921 gcgatcatgg taagcgccgc ctgctctgcc gcatcgccgt cctgatgccg tattgcatcg
    37981 aacagcgcct tatgttcctg gagcgtttgc ggcatgttgg cctcatcgcc catccaggtt
    38041 cgttcaaaaa ccgcccgctg cagcgaactg atcgcaatgc taagttgctg taacaccggg
    38101 ttatgcaccg actgcagcac cgcctcgtgg tagcgaatat ccgcttcgtt aaacgcttcg
    38161 cggtcctgat tgttggcaat catctcgttc agcgccgatt caatctgcgc cagatcgctg
    38221 gaagtcgcgc gctctgctgc ccaacgggca atcgccggtt ccaccagatt tcgcacttcg
    38281 ctcatggcac tgataagccg tgggtcgtag tcgttttcca acacccattg cagtacgtca
    38341 gtgtcgaggt aattccactg gttacgcggt gccacaaacg ccccgcgata acgtttcatt
    38401 tcaatcagcc gcttcgccat cagcgaacgg aacacctcac ggatgatgtt gcgcgaggtt
    38461 gcaaactctt cacagagctc cgcctcagcc ggaagtggcg agccaggtac gtatttgccg
    38521 tgaacgatct gtttacccag cgtaatgaca atgcgatcgg ttttattgag agtcatggag
    38581 agtccttgtg ctctgtatgt tcttctctac tttaccccga tcgatgcata acgcggcaac
    38641 tttgtagtac cagcgtgatg acgttcgcgt ttgccgtgtg agtaatgtag tacaaactta
    38701 tattgttgta ctacaattta gatcacaaaa agaacaatgc ataaaaaaat gacatgcgtc
    38761 gggcagaaat ctgaaaaggg atatcaggcg ctaaacagga gggaaagaag agtatgcttt
    38821 caacggctta gctactcgtt taaaggatta atcatgaagt tgaattttaa gggatttttt
    38881 aaggctgccg gtttattccc actggcgctg atgctttcag gctgtatctc gtatgctctg
    38941 gtttcccata ccgcaaaggg tagttcagga aagtatcaat cgcagtcaga caccatcact
    39001 gggctatcgc aggcaaaaga tagtaatgga acaaaaggct atgtttttgt aggggaatcg
    39061 ctggattacc ttatcactga tggtgccgat gacatcgtta agatgctcaa tgatccagca
    39121 cttaaccggc acaatattca ggttgccgat gacgcaagat ttgttttaaa tgcggggaaa
    39181 aagaaattta ccggcacaat atcgctttac tactactgga ataacgaaga agaaaaggca
    39241 ctggcaacgc attatggttt tgcctgtggt gttcaacact gtaccaggtc actggaaaac
    39301 ctaaaaggca caatccatga gaaaaataaa aacatggatt actcaaaggt gatggcgttc
    39361 taccatccat ttaaagtgcg attttatgaa tactattcac ccagaggcat tccggatggt
    39421 gtttccgcag cattactgcc agtgactgtt acgctggaca tcattactgc accgctgcaa
    39481 tttctggttg tatatgcagt aaaccaataa tcagtaagcg ggcaaacgcg tttatgctgt
    39541 ttgcccgtcc actgattaat tcagcacata cttctcaata gcaaacgcca cgccatcttc
    39601 aaggttggat ttggtgacaa agttcgccac ttctttcacc gaaggaatag cgttatccat
    39661 cgccacaccg acgcctgcat attcaatcat tgcgatatcg ttttcctgat cgccaatcgc
    39721 catgatttct tccggtttaa tacctaacac gtcggccagt gatttcaccc ccgtaccttt
    39781 gttaacgcgt ttatcgagga tttcgaggaa gtacggcgca cttttcagca cggtatattt
    39841 ctctttcact tcctgcggaa tacgcgcgat agcctggtcg aggatggcgg gttcatcaat
    39901 catcatcact ttcaggaact gggtattggg gtccattttc tccgcttcgc agaacaccag
    39961 cggaatggtg gcaacgaagg attcatgcac cgtgtagtag ctgatatcac ggttggcggt
    40021 gtacagcgtg gtgcggtcca gggcgtggaa atgagaaccg acttcgcgag agagtttttc
    40081 caggaaacga tagtcgtcat agctgagagc agtttgcgcc acggtgctac catcagcggc
    40141 cttctgtacc agcgcgccgt tataagtaat gcagtagtcg cccggctgtt ccatatgcag
    40201 ctctttcagg tagttgtgca cacctgcata cgggcgaccc gtcgttagca cgacattcac
    40261 gccacgggcg cgagctgcgg caatcgcatt tttaacggcg ggtgaaatgg tgtgatcggg
    40321 cagcagaagg gtgccatcca tatcgatagc aatgagtttg atagccatga gttccccagg
    40381 tagattagtt cctgacccat gctaacgcga ttccgctcaa aaatcagtac aacacccgag
    40441 ggaaaagggg gatgcaacgc gcgttgcgtg ctccccattt gcttagcgga agagtttccc
    40501 tttcagcagt tccatgcctg cggaaagcag atcgttattg gcttgtggag acacttcacc
    40561 ttgcggtgag agcgcatcaa taatcttcgg caattgttct gccagtaaac tggaagctgt
    40621 actggtatcc acgccaagtt tttgcccgag atcggacacc gcatttgtgc cgagcgccga
    40681 ttccagttgc tcgccactaa ccgattgatt gccctgttga ttactcagcc aggttgagag
    40741 aatggcccct aagccgccac tttgcagttt ttccagcagc acctgaatgc cgccctgctc
    40801 ctcaacccaa cttaaaatcg cctgatattt ccccgcatcg cctttcagaa aggcaccgac
    40861 aacttcatca aaaagcccca tgataatcac ctgtaaagcg ttacgtgttg acccaaaaag
    40921 tatagatctg cgggatgata attgcggatt gcagaaataa aaagggcgga gatgatctcc
    40981 gcccttttct tatagcttct tgccagatgc ggcgctaacg ccttacccgg cctacaaaat
    41041 catgaaaatt caatacattg caagattctc gtaggcctga taagcgtagc gcatcaggca
    41101 cgctcgcatg gttaacgcca ttaaatatcg atattcgccg ctttcagggc gttctcttca
    41161 ataaacgcac ggcgcggttc aacggcgtcg cccatcagcg tggtgaacag ctggtcagca
    41221 gcaatcgcat ccttaacggt aacgcgcagc atacgacgac tttccgggtc catggtggtt
    41281 tcccacagct gttccgggtt catctcgccc agacctttat aacgctggat ggagaggccg
    41341 cgacgggact ctttcaccag ccagtccagc gcctgctcga agctggctac cggctgacga
    41401 cgctcgccac gttcgataaa cgcatcttct tccagcaagc cacgcagttt ctcacccagc
    41461 gtgcagatac gacgatattc gccaccggtg ataaactcgt gatccagcgg atagtcagta
    41521 tccacaccgt gggtacgcac gcgaacaatc ggctcgaaca ggttttgctc ggcattggtg
    41581 tggacatcaa acttccactg gctgccgtgc tgttctttgt cgttcagttc gctgaccagc
    41641 gcgttcaccc agcgggtaac ggtctgctca tcagagaggt cggcttccgt cagcgtcggc
    41701 tgatagataa gctctttcag cattgctttc ggataacgac gctccatgcg gttgatcatt
    41761 ttctgcgtcg cgttgtactc agacaccagt ttctctaacg cttcgccagc caatgccggt
    41821 gcactggcgt tggtgtgcag cgttgcgcca tccagcgcga tggagatttg gtactgatcc
    41881 atcgcttcgt cgtctttaat atactgttcc tgcttgcctt tcttcacttt gtacagcggc
    41941 ggctgagcga tgtagacgtg accgcgttca acgatttccg gcatctgacg atagaagaag
    42001 gtcaacagca gcgtacgaat gtgcgagccg tcgacgtccg catcggtcat gatgatgatg
    42061 ctgtgataac gcagtttgtc cgggttgtac tcgtcacgac cgataccaca gccaagcgcg
    42121 gtgataagcg tcgccacttc ctgagaagag agcatcttat cgaagcgcgc tttctcaacg
    42181 ttgaggattt tacccttcag cggcagaatc gcctggttct tgcggttacg cccctgcttc
    42241 gcagagccgc ccgcggagtc cccttccacc aggtacagtt cggaaagcgc cggatcgcgt
    42301 tcctggcagt ctgccagttt gcccggcagg cccgctaagt cgagcgcacc tttacggcgg
    42361 gtcatttcac gcgcgcgacg cgccgcttca cgggcacggg cagcatcgat aattttgcca
    42421 accacgattt tcgcgtcggt tgggttttcc agcaggtatt ctgccagcag ttcgttcatc
    42481 tgctgttcaa ccgccgattt cacctcagaa gaaaccagtt tgtctttggt ctgggaggag
    42541 aatttcgggt ccggcacttt cacggaaacg accgcaatca ggccttcacg cgcatcgtca
    42601 ccggtggcgc tgactttggc ttttttgctg tagccttctt tgtccatgta ggcattcagg
    42661 gtacgggtca tcgccgcacg gaagcctgcc aggtgagtac cgccgtcacg ctgcggaatg
    42721 ttgttggtaa agcagtagat gttttcctgg aagccatcgt tccactgcaa cgccacttcg
    42781 acgccaatac cgtctttttc ggtggagaag tagaagatat tcgggtggat cggcgttttg
    42841 ttcttgttca gatattcaac gaacgccttg atgccacctt catagtggaa gtggtcttct
    42901 ttgccgtcgc gcttgtcgcg cagacgaatg gaaacgccgg agttgaggaa cgacaactca
    42961 cgcagacgtt tcgccagaat ttcatattcg aactcggtca cattggtgaa ggtttcgagg
    43021 ctgggccaga aacgcaccat ggtgccggtt ttttcagtct cgccggtaac cgccagcggg
    43081 gcctgcggta caccgtgttc gtagatctga cggtgaattt taccctcgcg ctggataacc
    43141 agctccagtt tttgcgacag ggcgtttact accgaaacac caacgccgtg cagaccgccg
    43201 gacactttat aggagttatc gtcaaattta ccgcctgcgt gcagaacggt catgatcact
    43261 tccgccgccg atacgccctc ttccgggtga ataccggtcg gaatgccgcg cccgtcatcc
    43321 tgtacagaga cagagttatc ggcgtgaatg gtgacgataa tttctttaca gtgacccgcg
    43381 agcgcttcgt cgatagcgtt atctaccacc tcgaatacca tgtggtgcag accggtgccg
    43441 tcatccgtgt cgccgatata catacccggg cgcttacgca ccgcatccag ccctttcagg
    43501 actttgatac tggaggagtc ataagaattc gacatcaacg tttctcgctc atttatactt
    43561 gggttaatcc gttattttac ccttttccac ggtaaacatc ttcgaatttt cgtccgacat
    43621 gtctataacg tgttcagcac tgatcgcgct gacaaagacc tgtgattgcg tcgcttttaa
    43681 gcggctggca agcaacccgc gacgctcatc atcaagctca gaggcaaaat catctatcag
    43741 gtagagacac cgccgcccgc tttcacgggt gaggaactct ccttgcgcca gacgtaaggc
    43801 gcacatcaac agcttaagct gcccacgcga taaggtatct tccaccggcg caccgtcggc
    43861 gcgaatgcgt aagtccgctt tgtgcgggcc atgcgcggtg taggttagct ggcgatcgcg
    43921 ttcaaaatta cgttccagta cctcagcata ttctgtctct ttctcccagc cgcgctggaa
    43981 agagaaagtc agagaaaact cagggagaaa ttgcttacag gtatcagcca tatcggccgc
    44041 gataccggcg ctgtactggg cgcgccaggt gctgatttgc tccgccagcg ggatcagttc
    44101 tttatcccac gggcgtagct gttcgtaacg tgtcacctgg cgcagcgccg cattgcgctg
    44161 cttgagcaat cgcttgagat tgctccaggc ggtgaaaaat ccgggttcgt tgtgaaagca
    44221 tccccagtcg aggaatgctc ttctgtattt ggggccgccg ttgagtaaag taaacccttc
    44281 tggcgttatc agctgcattg gcatcaggtg cgccagttcc gcgactttat gcccgtcagt
    44341 accgtcgatg cggactttgc tgtcgccctg tttgtccttg gttaagccaa tcgccgtctc
    44401 gcgctcttcg ccctgtaatc gcccatggag aacaaatgcc tcctgctcat ggcgaatgac
    44461 gcgaccaatc tgcaaactgc gaaacgcccg accatggccg agcgtataga tggcttccag
    44521 cacgctggtt ttgccactgc cgttggcacc taccagaaag ttaaagccgg gagataaagc
    44581 gagatccgcg gtttcaatgt tgcggaaatc gcggatcaac aagcgggtga gggacattac
    44641 agtctcattg gcatgacaac ataggcagcc gactgtgatg cggcatcttc aatctgcacg
    44701 ctggaaaccg aatcggtcag catcatgcgg acgttttcgc atttcagcgc gttcagaaca
    44761 tccagcacat agctgacgtt gaagccgatt tccatctccg caccgctata ggtaacgtcg
    44821 aggatctctt ccgcttcttc ctgttccggg ttgttggcgg tgattttcag ctggttttcg
    44881 ctgacataca ggcgcacgcc gcggaatttc tcgttagaga gaattgccgc acgggcaaac
    44941 gcctgcttga gcagatcgca gccagcttcc agatgtttgt ccggattctt cggcagaacg
    45001 cggcggtaat ccgggaagcg accatccacc agtttggagg tgaagataaa gtcgccaacg
    45061 tgggcgcgaa tattgttgct gccaatctgc acgcgcagcg gattgtcgcc gccgtcgagc
    45121 atacgcatca gttcaatcac gcctttacgc ggtacgatca ccgaatggct tggcaaagat
    45181 tgaccaattg gcattgaaca gaccgccaga cggtggccgt cggttgccac ggtgcgcagt
    45241 tcttcacctt cggtttcaaa cagcatacca tttaagtaat agcgaacgtc ctgatgcgcc
    45301 atcgaaaact gggtcgcttc aatcagacgc ttcatcgttg cctgcggcag ggtaaattcg
    45361 acttcactct gccagtcatc gaggttcggg aaatccgccg ctggcagggt agacagcgaa
    45421 aaacggctac gcccggagcg taccagcatc cgttcacctt ccagctgcac ggcaatttcc
    45481 gcgccttcag gcagaccacg gcagatatca aagaatttgc gcgccggaac ggtcgtcgct
    45541 cctggctcgt gtggctgaac cagcgcaaca cgtgccacca tttccatctc gagatcagta
    45601 ccggtcagcg acaacgtacc gtcagcaacc tgtaacagca gattaccgag aatcggtagc
    45661 gtaggacgac cacctaacgg accgctcacc tgttgtagcg gttttaataa atgctcacgt
    45721 tctacggtaa atttcatagg tttacgatga caatgttctg attaaatttg aaaaatcttc
    45781 tttgatatcg tggctctctt cacgcaactg ctcgatctta cggcaggcat gaagcaccgt
    45841 cgtgtggtca cgaccaccaa acgcatcgcc aatctccggc agactgtggt tagtcagctc
    45901 tttcgccagc gccatcgcca tctggcgcgg acgcgccacc gagcgggatc gacgcttgga
    45961 aaggagatcc gcgactttga tcttgtagta ctccgccacc gtcttctgaa tattgtcgat
    46021 ggtgaccagt ttttcctgca atgccagcaa gtcgcgcagc gcctcacgca cgaagtcgat
    46081 ggtgatcgcc cgtccggtaa agttggcatt ggcaatgacg cggttcagcg ccccttccag
    46141 ctcacgtacg ttagatcgta gacgcttggc gataaagaac gccacttcgc ccggcaaacg
    46201 aatgtcgttt tcgtcggcct ttttcatcag gatcgccaca cgggtttcca gctctggcgg
    46261 ttcgatcgcc acagtcagtc cccaaccgaa gcgggatttc aaacgatcct caacgccgtt
    46321 gatctctttc ggatagcgat ccgaggtgag aatgatctgt tgattacctt ccagcagggc
    46381 gttgaaggta tggaaaaact cttcctgaga tcgttcttta ttagcaaaaa actgaatatc
    46441 gtcgatcagc agtgcatcta cggaacggta gtagcgttta aactcttcga tcgcgttgtt
    46501 ttgcagggct ttaaccatgt cctgaacaaa gcgctcggag tgcatataaa ccactttggc
    46561 attcggcttg cgcgccataa tgccgttacc caccgcatgc agcaggtgag ttttacccag
    46621 acccgtgccg ccataaagga acaacgggtt ataggcaccg ccagggttat ccgccacctg
    46681 gcgagccgcc gcgcgcgcca gttggttaga tttaccttca acgaagttat caaacgtgtg
    46741 tttgacgttt acgttagaac gataggtcgg ttctgccggg gccgggacgt tatcccaacc
    46801 tgagcgcgta gaaggcgcag cacgttgcgg ctgcgtttgc gccacctgtg caggggccgc
    46861 gacgttgctc gtcactgccg cttgtggcgt ttgcgtcacc ggtttggtgc cgacttcaaa
    46921 acgcagctgt ggggcatccg ctccgcagaa actggttagc agtccattga tattattaag
    46981 gtacttgtcc cgtacccaat cgaggacaaa acggtttggc gcgtacaggg ccagcgtgtt
    47041 atcgctcagt tccgcctgca atgggcgtat ccacatactg aattctgtgg ctggtaactc
    47101 atcctgcaat cgggcaagac actgctgcca aagcgaaagt gacacggcgg actccactcg
    47161 aacaaaagtc gataatgact aaggctgaaa cattcatgat tgttgacgta cgtcgaaaag
    47221 accctgcttg agggtgacgc acgaaccgct gtctgcggtt atatgcccga tcaagatcct
    47281 gcaaaacgat cgggaccgcg gatcatagcc taaactgcgc aagagatctt ctgtttctca
    47341 cagattttcc cgatttatcc acaggacttt ccagaactcg ctaagtgtaa acgatcctgc
    47401 cgcgaggcgg gcacgattta cgccgcatat tggaaaattt aatgaccata gacaaaaatt
    47461 ggcttaatcg atctaataaa gatccaggac gatccttgcg ctttacccat cagcccgtat
    47521 aatcctccac ccggcgcgcc atgctggttt ccactggtgt gaggtcgtac attttccctg
    47581 cgaaaaggtg cggaaaagcg cggtaaataa ggaaagagaa ttgactccgg agtgtacaat
    47641 tattacaatc cggcctcttt aatcacccat ggcttcggtg tccatcgttt catttttcgg
    47701 cggatatcca ataaagccat tgaatttatt caagtttagg tagaaatcgc catgaaacgc
    47761 acttttcaac cgtctgtact gaagcgcaac cgttctcacg gcttccgtgc tcgtatggct
    47821 actaaaaatg gtcgtcaggt tctggcacgt cgtcgtgcta aaggccgcgc tcgtctgacc
    47881 gtttctaagt aataaagcta acccctgagt ggttaagctc gcatttccca gggagttacg
    47941 cttgttaact cccagtcaat tcacattcgt cttccagcag ccacaacggg ctggcacgcc
    48001 gcaaattacc attctcggcc gcctgaattc gctggggcat ccccgtatcg gtcttacagt
    48061 cgccaagaaa aacgttcgac gcgcccatga acgcaatcgg attaaacgtc tgacgcgtga
    48121 aagcttccgt ctgcgccaac atgaactccc ggctatggat ttcgtggtgg tggcgaaaaa
    48181 aggggttgcc gacctcgata accgtgctct ctcggaagcg ttggaaaaat tatggcgccg
    48241 ccactgtcgc ctggctcgcg ggtcctgata gccctcattc gggtctatca acgcctgatt
    48301 agtccgctac tcgggccgca ttgtcgtttc actccaacct gttcaagcta cggaattgag
    48361 gcattgcgca ggtttggagt gataaaaggc agttggttga cggtgaaacg cgtattaaaa
    48421 tgccaccctt tacaccctgg tggtgacgat cccgtcccgc ccggaccatt tgataccaga
    48481 gaacactaac gatggattcg caacgcaatc ttttagtcat cgctttgctg ttcgtgtctt
    48541 tcatgatctg gcaagcctgg gagcaggata aaaacccgca acctcaggcc caacagacca
    48601 cgcagacaac gaccaccgca gcgggtagcg ccgccgacca gggcgtaccg gccagtggcc
    48661 aggggaaact gatctcggtt aagaccgacg tgcttgatct gaccatcaac acccgtggtg
    48721 gtgatgttga gcaagctctg ctgcctgctt acccgaaaga gctgaactct acccagccgt
    48781 tccagctgct ggaaacttca ccgcagttta tttatcaggc acagagcggt ctgaccggtc
    48841 gtgatggccc ggataacccg gctaacggcc cgcgtccgct gtataacgtt gaaaaagacg
    48901 cttatgtgct ggctgaaggt caaaacgaac tgcaggtgcc gatgacgtat accgacgcgg
    48961 caggcaacac gtttaccaaa acgtttgtcc tgaaacgtgg tgattacgct gtcaacgtca
    49021 actacaacgt gcagaacgct ggcgagaaac cgctggaaat ctccaccttt ggtcagttga
    49081 agcaatccat cactctgcca ccgcatctcg ataccggaag cagcaacttc gcactgcaca
    49141 ccttccgcgg cgcggcgtac tccacgcctg acgagaagta cgagaaatac aagttcgata
    49201 ccattgccga taacgaaaac ctgaacatct cttcgaaagg tggttgggtg gcgatgctgc
    49261 aacagtattt cgcgacggcg tggatcccgc ataacgacgg taccaacaac ttctataccg
    49321 ctaatctggg taacggcatc gccgctatcg gctataaatc tcagccggta ctggttcagc
    49381 ctggtcagac tggcgcgatg aacagcaccc tgtgggttgg cccggaaatc caggacaaaa
    49441 tggcagctgt tgctccgcac ctggatctga ccgttgatta cggttggttg tggttcatct
    49501 ctcagccgct gttcaaactg ctgaaatgga tccatagctt tgtgggtaac tggggcttct
    49561 ccattatcat catcaccttt atcgttcgtg gcatcatgta cccgctgacc aaagcgcagt
    49621 acacctccat ggcgaagatg cgtatgctgc agccgaagat tcaggcaatg cgtgagcgtc
    49681 tgggcgatga caaacagcgt atcagccagg aaatgatggc gctgtacaaa gctgagaagg
    49741 ttaacccgct gggcggctgc ttcccgctgc tgatccagat gccaatcttc ctggcgttgt
    49801 actacatgct gatgggttcc gttgaactgc gtcaggcacc gtttgcactg tggatccacg
    49861 acctgtcggc acaggacccg tactacatct tgccgatcct gatgggcgta acgatgttct
    49921 tcattcagaa gatgtcgccg accacagtga ccgacccgat gcagcagaag atcatgacct
    49981 ttatgccggt catcttcacc gtgttcttcc tgtggttccc gtcaggtctg gtgctgtact
    50041 atatcgtcag caacctggta accattattc agcagcagct gatttaccgt ggtctggaaa
    50101 aacgtggcct gcatagccgc gagaagaaaa aatcctgatt cggtgagttt tcgctaaaat
    50161 aagggcggtc agttgaccgc cttttttctt ttcgtagggc ggataagcac cgcgcatccg
    50221 ccacacaaag caacaggaac atcatgagcg ataatgacac tatcgtagcc caggccacgc
    50281 ctccgggacg tggcggcgtt ggcatcctgc gcatctccgg cttcaaagcc cgtgaagttg
    50341 ccgaaaccgt gctgggtaaa ctacctaagc cgcgctacgc cgattatctt ccgtttaaag
    50401 acgccgacgg cagcgtgctc gatcagggga ttgcgctatg gttccctggc ccgaactcgt
    50461 tcaccggcga agatgtgctg gaactgcaag gtcatggcgg tccggtgatc ctcgacctgc
    50521 tgttaaaacg cattctgacc attcccggcc tgcggattgc tcgccctggt gagttttccg
    50581 aacgcgcgtt tcttaacgat aaactcgact tagcccaggc cgaggcgatt gccgatctta
    50641 tcgacgccag ttcggaacag gcggcccgtt cggcacttaa ctcgctgcaa ggcgcattct
    50701 ccgcacgggt caaccatctg gtggaagccc tcacccactt gcgcatttac gtcgaagcgg
    50761 caattgattt ccctgatgaa gagatcgatt tcctctccga cggcaaaatt gaagcccagc
    50821 ttaatgacgt gattgccgaa ctcgatgcag tgcgtgctga agcacgtcag ggtagtttgt
    50881 tgcgcgaagg gatgaaggtg gtgattgccg gacgtcctaa cgccggtaaa tcgagcctgt
    50941 taaacgcgct ggcgggccgt gaagcagcaa tcgtaactga tatcgccgga accacacgtg
    51001 acgtgctgcg tgagcatatc cacattgacg gaatgccgct gcatatcatc gataccgctg
    51061 ggctacgtga agccagtgac gaagtggaac gtattggtat cgagcgcgcg tggcaggaaa
    51121 ttgaacaggc cgaccgcgtg ctgtttatgg tcgatggcac cacaacagac gccgtggatc
    51181 cggcagagat ctggccggaa tttattgccc gtctgccagc gaaactgccg atcaccgtgg
    51241 tgcgcaataa agccgatatc accggcgaaa cgctgggaat gagtgaagtg aacggtcacg
    51301 cgttaattcg tctctcggca aggactggtg aaggcgtgga cgtgctgcgt aaccatctca
    51361 aacagagcat gggctttgac accaacatgg aaggcggctt cctggcgcgt cgtcgccacc
    51421 tacaggcgct ggaacaggca gcggaacatc tacaacaggg caaagcgcaa ctgttgggag
    51481 cctgggcagg tgaactgctg gcggaagagt tgcgtctggc acagcagaac ttaagcgaaa
    51541 tcaccgggga atttacttca gacgacctgc tggggcggat tttctccagc ttctgtattg
    51601 gtaagtaacc gcgcttacga agccgtattc tgactgtcag atgcggcttc gcttcattgt
    51661 tagcactcct gttattcctc aacccttttt ttaaacatta aaattcttac gtaatttata
    51721 atcttaaaaa aaagcattta atattgctcc ccgaacgatt gtgattcgat tcacatttaa
    51781 acaattttag aatagacaaa attcttgagt attatactgt agtctcgtgt ctttcgagga
    51841 taagtgcatt atgaatatct tacatatatg tgtgacctca aaatggttca atatcgacaa
    51901 taagattgtc gatcaccgcc cttaatttac ccttctgtag ccatcaccag agccaaaccg
    51961 attagattca atgtgaacga ttagtttgct atatcttaat tttgcctttt gcaaaggcca
    52021 tctctcgttt atttacttat tttagtaaat gatggtgctt gtatatatac atggcgaatt
    52081 aatggatatt gcagatgtaa tattcacagg gatcactgta attaaaataa atgaaggatt
    52141 atgtaatgga aaactttaaa catctccctg aaccgttccg cattcgtgtt attgagccag
    52201 taaaacgtac tactcgcgct tatcgtgaag aagcaattat taaatccggt atgaacccgt
    52261 tcctgctgga tagcgaagat gtgtttatcg atttactgac cgacagcggc accggggcgg
    52321 taacccaaag tatgcaggca gcgatgatgc gcggcgacga agcctacagc ggcagccgca
    52381 gctactatgc gttagccgag tcagtgaaaa atatctttgg ttatcaatac accattccga
    52441 ctcaccaggg ccgtggcgca gagcaaattt atattccggt actgattaaa aaacgcgagc
    52501 aggaaaaagg cctggatcgc agcaaaatgg tggcattctc taactatttc tttgatacca
    52561 cgcagggcca tagccagatt aacggctgta ccgtgcgtaa cgtctatatc aaagaagcct
    52621 tcgatactgg cgtgcgttac gactttaaag gtaactttga ccttgaggga ttagaacgcg
    52681 gtattgaaga agttggcccg aataacgtgc cgtatatcgt tgcaaccatc accagtaact
    52741 ctgcaggtgg tcagccggtt tcactggcaa acttaaaagc gatgtacagc atcgcgaaga
    52801 aatacgatat tccggtggta atggactccg cacgctttgc tgaaaacgcc tatttcatca
    52861 agcagcgtga agcagaatac aaagactgga ccatcgagca gatcacccgc gaaacctaca
    52921 aatatgccga tatgctggcg atgtccgcca agaaagatgc gatggtaccg atgggcggct
    52981 tgctgtgcat gaaagacgac agcttctttg atgtgtacac cgagtgcaga accctttgcg
    53041 tggtgcagga agggttcccg acatatggcg gcctggaagg cggcgcgatg gagcgtctgg
    53101 cggtaggtct gtatgacggc atgaatctcg actggctggc ttatcgtatc gcgcaggtac
    53161 agtatctggt cgatggtctg gaagagattg gcgttgtctg ccagcaggcg ggcggtcacg
    53221 cggcattcgt tgatgccggt aaactgctgc cgcatatccc ggcagaccag ttcccggcac
    53281 aggcgctggc gtgcgagctg tataaagtcg ccggtatccg tgcggtagaa attggctctt
    53341 tcctgttagg ccgcgatccg aaaaccggta aacaactgcc atgcccggct gaactgctgc
    53401 gtttaaccat tccgcgcgca acatatactc aaacacatat ggacttcatt attgaagcct
    53461 ttaaacatgt gaaagagaac gcggcgaata ttaaaggatt aacctttacc tacgaaccaa
    53521 aagtattgcg tcacttcacc gcaaaactga aagaagttta attaatacta cagagtggct
    53581 ataaggatgt tagccactct cttaccctac atcctcaata acaaaaatag ccttcctcta
    53641 aaggtggcat catgactgat caagctgaaa aaaagcactc tgcattttgg ggtgttatgg
    53701 ttatagcagg tacagtaatt ggtggaggta tgtttgcttt acctgttgat cttgccggtg
    53761 cctggttttt ctggggtgcc tttatcctta tcattgcctg gttttcaatg cttcattccg
    53821 ggttattgtt attagaagca aatttaaatt atcctgtcgg ctccagtttt aacaccatca
    53881 ccaaagattt aatcggtaac acctggaaca ttatcagcgg tattaccgtt gccttcgttc
    53941 tctatatcct cacttatgcc tatatctctg ctaatggtgc gatcattagt gaaacgatat
    54001 caatgaattt gggctatcac gctaatccac gtattgtcgg gatctgcaca gccattttcg
    54061 ttgccagcgt attgtggata agttcgttag ccgccagtcg cattacctca ttgttcctcg
    54121 ggctgaagat tatctccttt gtgatcgtgt ttggttcttt cttcttccag gtcgattact
    54181 ccatcctgcg cgatgccacc agcaccactg cgggaacgtc ttacttcccg tatatcttta
    54241 tggctttgcc ggtgtgtctg gcgtcatttg gtttccacgg caatattccc agcctgatta
    54301 tttgctatgg aaaacgcaaa gataagttaa tcaaaagcgt ggtatttggt tcgctgctgg
    54361 cgctggtgat ttatctcttc tggctctatt gcacgatggg gaatattccg cgcgaaagct
    54421 ttaaggcgat aatctcctca ggcggcaacg ttgattcgct ggtgaaatcg ttcctcggca
    54481 ccaaacagca cggcattatc gagttttgcc tgctggtgtt ctctaactta gctgttgcca
    54541 gttcgttctt tggtgtcacg ctggggttgt tcgattatct ggcggacctg tttaagattg
    54601 ataactccca cggcgggcgt ttcaaaaccg tgctgttaac cttcctgcca cctgcgttgt
    54661 tgtatctgat cttcccgaac ggctttattt acgggatcgg cggtgccggg ctgtgcgcca
    54721 ccatctgggc ggtcattatt cccgcagtgc ttgcaatcaa agctcgcaag aagtttccca
    54781 atcagatgtt cacggtctgg ggcggcaatc ttattccggc gattgtcatt ctctttggta
    54841 taaccgtgat tttgtgctgg ttcggcaacg tctttaacgt gttacctaaa tttggctaaa
    54901 tccttcaaga agccagccat tcgctggctt cttgcctctc aggaaatcac ttatgtccaa
    54961 atggcaactc gcctgattct ccttcaccac gtatgctttg cgtcacctta ctattaggac
    55021 gctttagccc atgtcccgct ttttaatttg tagttttgcc ctggttttac tttatcccgc
    55081 cgggattgat atgtacctcg ttggtttacc gcgcatcgcc gacgatctca atgccagcga
    55141 agcgcagttg catattgcgt tctccgttta tctggcgggc atggcagctg cgatgttatt
    55201 tgccggtaaa gtggccgatc gttcagggag aaagcctgtc gccatccccg gcgcggcgct
    55261 atttattatc gcttcggtgt tctgttcact ggctgaaacc agcacgttat ttcttgcagg
    55321 ccgatttcta caggggttgg gcgcaggctg ttgttacgta gtggcgttcg ccattttgcg
    55381 cgacacgctg gatgatcgac gtcgggctaa agtgctgtca ttactcaacg gtattacctg
    55441 catcattccg gtgttagcgc cagtgctcgg acatctgatt atgcttaaat tcccgtggca
    55501 gagtctgttc tgggcgatgg caatgatggg catcgcggta ctgatgttgt ctttgtttat
    55561 tttaaaagaa acgcgcccag cgtcccccgc tgcttcggac aaaccacgag aaaatagcga
    55621 gtcgctgctt aatcggtttt tcctcagccg tgttgttatc accaccctca gcgtttcggt
    55681 gatcctcact ttcgtcaata catcgccggt attgctgatg gaaatcatgg gttttgagcg
    55741 cggagaatac gccaccatta tggcgttgac tgctggcgtc agcatgaccg tttcattctc
    55801 cacgccattt gcgctgggaa tttttaagcc acgtacgttg atgatcacct cgcaggtgtt
    55861 attccttgca gcggggatca cccttgccgt ttcaccttcc catgcggttt ctctgtttgg
    55921 tatcacgctg atttgcgccg gtttctcggt aggttttggc gtagcgatga gtcaggcgtt
    55981 aggaccattt tcattacgcg cgggcgtagc cagctcgacc ttaggtattg cgcaggtttg
    56041 cggttcgtca ctgtggattt ggctggcagc ggtggttggt atcggcgcat ggaatatgct
    56101 gatcgggatt ctgattgcct gtagcatagt gagcctgttg ctgattatgt tcgtcgcgcc
    56161 tggacgcccc gttgccgctc atgaagaaat ccatcaccac gcttgatctc aatctgctgc
    56221 tctgtctgca actgctgatg caggagcgca gcgtgaccaa agcggcgaag cggatgaacg
    56281 tgaccccttc agcggtgagt aagtcgctgg caaagttaag agcgtggttt gacgacccgc
    56341 tctttgtgaa ctcaccgctg ggcctgtcgc ccacaccgct aatggtcagc atggagcaaa
    56401 atctggcgga atggatgcaa atgagcaatc tgctgctgga taaaccgcac caccagacac
    56461 cgcgcggcct gaagtttgag ttggcggcgg aatcgccgct gatgatgatc atgcttaatg
    56521 cgctgtcgaa acggatctac caacgttacc cgcaggcgac catcaaacta cgtaactggg
    56581 attacgattc cttagatgcc attactcgtg gtgaagtgga tattggtttt tccggtcgcg
    56641 aaagccatcc tcgctcgcgg gagctgttaa gctcgctacc gttagccatt gattatgaag
    56701 tgctgtttag tgatgtaccc tgcgtctggt tacgcaaaga tcatccggca ctgcatgaaa
    56761 cgtggaatct ggacaccttt ttacgttatc cgcatatcag catttgctgg gaacagagcg
    56821 acacctgggc gctggacaat gtgttacagg agctggggcg cgaacgcacg attgctatga
    56881 gcctgccgga atttgagcag tcactgttta tggcagcgca acccgacaat ctgctactgg
    56941 cgaccgcgcc gcgctactgt cagtactaca atcaactcca tcaactgccg ttggttgctc
    57001 ttcctctccc gtttgacgaa agccagcaaa aaaagctgga agttcctttt accctgctgt
    57061 ggcataaacg gaacagccat aatccgaaga tcgtctggtt acgggaaacc attaaaaacc
    57121 tttacgcgtc gatggcataa ccgaatcgta tgaaacgcga cccaatttca caataaaatg
    57181 taaaaaagtt gtaataagct tgtctgaatc gaacttttag ccgctttagt ctgtccatca
    57241 ttccagtaaa tgattactct tgtattcata atggaccatt aagcatggag cgaaaaatgg
    57301 cgactcactt tgcccgaggg attttaacgg aaggacatct gatttctgtt cgtctcccct
    57361 cccagtgtca tcaagaagcc cgaaacattc cccctcatcg tcaaagccgt tttctggcgt
    57421 ctagaggttt actcgcagaa ctgatgttca tgctgtatgg cattggcgaa ttgccggaaa
    57481 tcgtcaccct gccgaaaggt aaaccggttt tcagtgataa aaatttgcct tcgttttcta
    57541 tttcctatgc cgggaatatg gttggcgtgg cgttaacaac cgaaggtgaa tgtggtctcg
    57601 atatggaact acagcgtgcg acgcgcgggt ttcacagccc acacgcgccc gataaccaca
    57661 ccttttccag caatgaatcg ctatggatca gtaaacaaaa cgatcctaac gaagcgcggg
    57721 cgcagctcat cacgctgcgc cgaagcgtgc taaaactaac cggtgatgtt ttgaatgacg
    57781 atccgcgcga tctgcagctg ctgcccattg ccggacgcct gaaatgtgct catgtaaatc
    57841 atgtagaagc gttatgcgac gcggaggacg tgctggtgtg gtccgtggcg gtcacgccca
    57901 cgattgaaaa gctcagtgtc tgggagttcg atggcaaaca cggctggaaa agcctgccgg
    57961 atattcacag ccgcgccaac aatcctacca gccggatgat gcgttttgcc cagctctcta
    58021 ccgtgaaggc tttttcgcca aattgataga caaccacagg agtcatcatg tctgaaaaat
    58081 tgcaggtggt tacgttactg gggagcctgc gcaaaggctc atttaatggc atggttgcac
    58141 gtaccctgcc gaaaattgct ccggcgagca tggaagtcaa tgcgttacct tccattgccg
    58201 acattccctt gtatgacgct gacgtacagc aggaagaagg ttttccagca acggttgaag
    58261 ctctggcgga acagatccgt caggctgacg gtgtggtgat cgtcacgccg gaatataact
    58321 actcggtacc gggtgggctg aaaaatgcca tcgactggct ttcccgcctg ccggatcaac
    58381 cgctggccgg taaaccggtg ttgattcaga ccagctcaat gggcgtgatt ggcggcgcgc
    58441 gctgtcagta tcacctgcgc cagattctgg ttttcctcga tgcaatggtg atgaacaagc
    58501 cggaatttat gggcggcgtg attcagaaca aagttgatcc gcaaaccgga gaagtgattg
    58561 atcagggtac gctggaccac ctgaccgggc aattgaccgc atttggtgag tttattcagc
    58621 gagttaagat ctaaataaaa aacccgccag caatcatgca tggcgggttt ttaacgcgct
    58681 atcgatttta gtgagcgtcg ataaagacaa tcttcaggat aaacagcagc gcaacgatga
    58741 ttacgcacgg gcttagatca cgcagacgtc cggtaccgat tttcatcacg cagtaggaga
    58801 taaagcccag cgcgatacct tcggtaatcg agaagctgaa cggcatcatc acggcggtaa
    58861 taaacgccgg aacagattca gtaagatcct gccagttcac gcgtgccaga ctggaagtca
    58921 tcagcacgcc aacgtaaatc agcgcaccag ctgcagcgta gcctggcacc atccccgcca
    58981 gcggcgacag aaagataacc agcaggaaca gcagaccaac aaccactgcc gtcagaccgg
    59041 tacgaccgcc aaccgatacg ccggaagagg actcaatata agccgtaacg gaagaagtac
    59101 cgataaacga accggtcacg gaagagatac tgtcgacata cagcgcctgc ttcatgcgcg
    59161 ggaatttacc cttctcatcc gccaggcctg ctttatcggt cacgccaatc agcgtaccgg
    59221 aggagtcaaa caggttgacc agcatgaaag agaaaatcac ccctgccagc ccgaggttaa
    59281 acgacccggc taaatctaca tgacccacaa ctgtcattac gctcggcggc gcagaaacga
    59341 tgccattgta gtgcacatca cccagcatcc agcccagcag cgtcgtcacc acgatagaaa
    59401 ccagcaccgc tgcgtgaatg ttgcgcgagg ccagaatagc aatgatgaag aagccgagga
    59461 tccccagcag cacgctgtga gaagtcaggt taccgatgct gaccagcgtt tccgggttag
    59521 cgacaatcac acctgcattc ttcagtccca tcataccaat gaacagaccg ataccgctgg
    59581 tgatgcccac acgcagactt accggaatgt tggcaatcat ccagtagcga acgcggaaaa
    59641 tcgtcagtaa cagcagacca atcgcacccc agaagattgc gcccatcccg acttgccacg
    59701 gcaagcccat cgcctgtaca acgacaaaag cgaagaacgc attcaggccc atagcgggtg
    59761 ccagtgcaac tggcaggtta gcaaacagtc ccatcataat actgccgaat gcagcgatca
    59821 gacaggtagt gacgaagacg gcgctggtat ccatgccagc aacgccaaga atttgcgggt
    59881 taacaaaaac gatgtaaacc atcgtcagga aggtggtaaa accggcgatc acttcggtcc
    59941 gtgccgtcgt gccatgttcg cgcagtttaa acacgcgttc cagcatcccc tggccagaag
    60001 cctgggttgt gtgttgttga ctcattatct atttccgaac aaggagggaa aatccgtcgc
    60061 tatcgtatac caaaatgaga caatatggac ggctgaagat aacttttttt cattgtattt
    60121 gcttatacgg caacgattgc gtcatgcgaa ttggcatgac gaaaacgtta aactaacgat
    60181 aaaggaaaga catgtcccag atagaagcgg tatttttcga ctgcgacggt acgctggtcg
    60241 acagtgaagt catttgctcc cgcgcatatg taacgatgtt tcaggaattt ggtattacgc
    60301 tcgatcctga agaggtattc aaacgtttca aaggtgtaaa actgtacgaa attatcgata
    60361 ttgtttccct tgaacatggt gttacgttag cgaaaacaga agctgaacac gtttaccgtg
    60421 cagaagtcgc tcggctgttc gattcagaac tggaagccat cgaaggggct ggagcgctcc
    60481 tgtcagcgat cactgcgcca atgtgtgtgg tatctaacgg cccaaataac aaaatgcagc
    60541 attctatggg caagctgaat atgttgcact acttcccgga taaactgttc agcggctacg
    60601 atattcagcg ctggaagcca gacccggcgt taatgttcca tgcggcaaaa gcgatgaatg
    60661 taaatgtaga aaactgcatt ctggttgatg actcagttgc cggtgcgcaa tctggtatcg
    60721 acgcaggtat ggaagtgttc tacttctgcg ccgacccgca caataagccg atcgttcacc
    60781 cgaaagtcac cacctttacc catctttcgc agttaccgga actgtggaaa gcgcgtggtt
    60841 gggatattac ggcatagttc ttcacactcc cttcacttac cccgcttaaa ttggcgctca
    60901 aaggtaagta aagggagttt gatatgtctg tttcacgtcg ggtaatacat cacggacttt
    60961 attttgcggt tttaggaccg ttaattggtg ttctgtttct tgtcctctac atattcttcg
    61021 caaaagaacc gctggttctt ttgcgaagaa tacaggtact tccattgttt ctcttattgt
    61081 cgattactac gggagttatt cctgcattgt taaccggcgt gatggtcgcc tgtctgccgg
    61141 aaaagatcgg gtcacagaaa aattatcgtt gtctggctgg tggcataggt ggcgtcgtta
    61201 tcaccgagat ctattgtgca gttattgtac atattaaggg catggcttcc tcggagttgt
    61261 ttgaaaacat tctttctggt gacagtctcg ttgtccgcat cattcctgca ttgctggcag
    61321 gtgtggtgat gagcagaatc attacccgtc tgcccggatt ggatatttca tgtcctgaaa
    61381 cagactcttt aagttaagcg ggatacttta tctttgggct actcaaaagc agacaggatg
    61441 ttactatgac tcaaaatatc aggccgttac cccaattcaa atatcatccc aagccactgg
    61501 aaacaggcgc atttgaacag gataaaaccg tagagtgcga ttgctgtgaa caacagacgt
    61561 cagtttatta ctcgggtccc ttttattgcg ttgatgaagt tgaacatctc tgtccgtggt
    61621 gtattgcgga cggttctgct gctgaaaagt ttgcaggtag ttttcaggat gatgccagca
    61681 tagaaggtgt tgaatttgag tatgatgaag aggacgaatt tgccggtatt aagaacacat
    61741 atcctgatga aatgctgaaa gagttggttg aacgcacgcc aggttatcat ggatggcaac
    61801 aggaattctg gcttgcgcat tgtggcgatt tctgtgcttt tatcggctat gtgggctgga
    61861 atgatataaa agatcgcctc gatgaatttg ccaaccttga agaagattgt gagaatttcg
    61921 gtattagaaa ttctgatcta gctaaatgcc tgcaaaaggg tggtgattgt cagggttatc
    61981 tcttccgctg tctccactgc ggcaagctga gactgtgggg tgatttttcg tagttattta
    62041 aataatgaga acaggccgga gcgtaattca tacatccggc cttatttctt cagcttaacc
    62101 gagcgctaat tctgcggcag cggctttatc agcgattacc atcagcgaag gatgcagctg
    62161 caacacggaa gctggaacat cttcggtaac cggaccttgc agaacatttt tcagtgcctg
    62221 cgctttacct gcgccactga caattatcag caagtttttc gccgccatga tgcttttcgg
    62281 ccccatcgtc acgtagctgt caggcactaa cgaaaagtcg ccgcccaact caccatgcgc
    62341 cacaatatca accatctctc cctggatcgg gaactccacg gtttgctcat ggaaatgggt
    62401 cgtattcggc aaattgccac aaaaatgacc atctgcacct aatcccagca ccaccaaatc
    62461 caggccgcct tcacgcgcca gtttctgatc atgctcgcgg tagttatcaa tagtgagctt
    62521 ctggatattc tcttctttga tccccgcagg ggtgaaaaac agattacgca gattggtaat
    62581 cgttacacct tctccctctt tgccgcgaaa gggaatttca tcgaaattat agaaatagca
    62641 gttatcgtac cagggcttac ctttaaccag ggtggtgagg tattcataca tgcctttggg
    62701 cgtgctaccg gcggtaattg ccaggttaac acgacgcgtc ttcgacatat aaccaagcag
    62761 atggtgtgcc gcgacacggc tcatttcctg gtaatcttcg gtaatgatta atttcatctt
    62821 agtgccttat tttatttaaa taatttctgt acgaaggctg cataggcagg ccgccagaca
    62881 tccatttcat ggttcaggcc gggatattcc tggtaatcaa acttaatttt tttctgctca
    62941 agctcagttt tcagcccggc gatatccttg ccggttacga catctttatc accaacgacc
    63001 acagtaaaat tacgtagttg ctggttaata gctgccggat cgttcagccg ggccgcgaca
    63061 ccttcatccg gtacggttgt cgtggtaaca ccactgaatg tggccagcca gccaaagctt
    63121 tccagatgat tcattcccga taccagcgcc tgatacccac cttgtgaaag ccctgccagt
    63181 gcgcgaccat cggcatcttt actgacgtta aaacgcttgc taatcagcgg gataatatcg
    63241 ttcatcagtt cgcgatctgc cgctttagca ttcagcggat aaaagacttt acgtctttcc
    63301 tgaggcacga aatcttcggg aataatgccc ttcgcatcgg tttcggtatc cgggatcacc
    63361 accagcatcg gtttaatttt cccttcagcc agcaggttat ccatgatttg cgggatacgc
    63421 ccctgatcga tagcggaacg tccggtatca ccaaaaccgt gatagaaata gagcactggc
    63481 aaaggctcgc ccatgccggt gtatcctggc ggggtccaga catacatctg acgttcagat
    63541 tgcaatgcgt tggagtggta agttatggcg atcaaatcac catgcgcaac agaacgcgta
    63601 tccagataac tgcctggcac cagaatcata ctggagttaa cctggcgctg aggcttagtc
    63661 attgcggtgc ctgtatcaat gctgcgtaca ccatcaacat tgaaaaaata ctcgtacagg
    63721 ttgcctttca ggataggtgt gcgccacgac cagactcctg cttcgtcttt ggtcatcggg
    63781 tgaatattgt ccagaaccgg aacacccacc actacagaga cattttttgc cccaggggca
    63841 aagtagcgaa aggtcacgct gttatcggca ttgacctgag tcacatactg tttcaccggg
    63901 atagtgggtg ccgggctggc tggcatatcc gctgctatgg cccactgagc agaaataccg
    63961 ctggcaatag ccagcgttaa agcagcaatt tttatattca tcgtaatatt cctttcatta
    64021 agttccatta ccaccagatt tcagcctggg caccgacagc aaactggtcg tctttattgt
    64081 cttcgaaggt gaagccatcc agttcgtttt ccagggcttt gatatacgtg gcgtagaaac
    64141 gaatttccgg acgcgaggtc aacatactgg tattgacttt aaaggtatgg aagagcgtgg
    64201 ttttataacc agactcatta aatttattac tattcgcatc tttgttttgc tgggtgaaat
    64261 agcccagttc aacacctgtc tggttatatt ggtcccaaat ataggccggg cgaacaaccg
    64321 cacgaataga ttcgaaatca gagtgtgcgc ctgtttcgta gctataaata tcgttaccga
    64381 aggagtaaac aatcgcgtta gccacaatga aatgatcgcc gatataggct tcgccctgtg
    64441 aagtcagacg aactgctgtt ccgccggtgt gatcaccata ataacgacca ttaaaggtgg
    64501 taaatggact tgcgccagca taacggccaa agttactggc gatagagtta ttcgcaacca
    64561 ggaaggagaa ttcgttgaag ccacctttat caaatttctg cgttaaagat gtgccaaaca
    64621 tccaggtata tttccagtca taatagccgt tattatcctg attatctttt tccgatgcgc
    64681 tttcgtttgc cgtgacataa cgaccactca ccattaaggt cgctttatcc cataacggga
    64741 tatctttata gcgtaaatca atagcattgg tattaatctg ctgtttgttt tgcaggctgc
    64801 gatcgtaatc atcgacatct tcgcgaacca gcgcgatatc aattttaccc ggaccgactt
    64861 tccagttttc cagacctaca cccgctgcgg catcagtacg ctgcgttttc cagtcaagca
    64921 tctggatttc aattttcggc gcaccgtgtt tacccaccca gaaatcagcc tctggcgcaa
    64981 agggcaggaa acctttggtg gtaacgtaca tatcggagaa ctgcataaag ttctcgccac
    65041 cggcgttatc gccaaaccag ccggtagagt actgctgacc aacgttacca tccatcatca
    65101 caacggcatc aacccgtttg ccgttttcgt tgtagacacg ttgttttaac tgcaaatcaa
    65161 accagccgga gtattcgtta ccaaagcggc ccagagaacc aatcgcccat gatttaggtg
    65221 aaccatgaga ggcggtcccc caaccagaac ggtaatagcc gttgtaacta aagccaattt
    65281 catctttcac aaacttactg aaatctttca gagtcatgga agaataaatc gagcctgtct
    65341 cactggcatt tttctcttca tttttgacca gtacagcatc aggttttgcg gcactactgg
    65401 tcgggaacgg attggcggca tacccttgat cattcgtact tacgctacga ttcaccgtcg
    65461 ctggcgtata ttttttcttc tcttcatctt tatacttttt gagttcgctt tgcgtttctc
    65521 ttaacgcttt ttctaataac tcaaggcgat gttccaccgt taatgattca gccaatgatt
    65581 gtgcagaaaa ggctaacggt gccattaata agatggcaga ggtaataaga tttcgtctaa
    65641 acataatatc cctttatggt gcaaagaaag aattaacgta tcgcatccag actgttctga
    65701 atgcgacgat aattaaggtg ctttattggt tattttttta atgacagccc ccgcgttttg
    65761 atcacttctg cataccatcc gaagcttttc ttacgcgttc ttgtgaggct tccttcgcca
    65821 ttatcatcac gatccacata aataaagccg tagcgcttag acatttgtga atgagatgca
    65881 ctgactaaat caattggccc ccaactggtg taccccataa tatccacacc atcggcaatc
    65941 gcttcattta cctgtaccag gtgatcgttt aaataggcaa ttcgataatc gtcctgtatc
    66001 gaaccatccg cttcaacgct gtcttttgcg cctaatccgt tctcgacaat aaataacggt
    66061 ttttgataac gatcccaaag cgtatttaac agaacccgta atccaaccgg atcaatttgc
    66121 cacccccact ctgaactttt cagatgcgga ttggggatca tattcagtat gttgccctgc
    66181 gcatttttat taatgctttc gtcgtgggaa acacaaccag tcatgtaata actaaaagag
    66241 atgaaatcta cggtatgttt taaatcttct gcgtcacttt cagtcatctc aatggtgata
    66301 ttgtggtcgc ggaagaaacg ctgcatatag ccgggatact gaccacgcgc ctgaacatca
    66361 ccaaagaaca tccagcgccg gttctcttcc atggcctcca acatatcctg tggctggcag
    66421 gtgagggggt aaaccagccc gccgagaagc atattgccga ttttcgcttc ggggatcagg
    66481 ctatgacagg ctttaactgc ccgcgcactg gcaaccagtt gatgatggat cgcctgataa
    66541 acttccgcct cgccactctc ttctgccagc cccacgcccg tgaatggcgc gtgtaacgac
    66601 atattgattt cattaaacgt cagccataac gctactttat gttggtagcg ggtaaagacc
    66661 gtgcgggcgt aatgctcgaa gtgatcgatg accgcccgat tagcccaacc gccgtagttt
    66721 ttcaccagcc catatggcat ttcgtaatgg gataacgtta ccagcggctt gatccccgcc
    66781 tgcgccattt catcaaacag ccgatcgtaa aacgctaacc ccgcttcatt cggttcggct
    66841 tcgtcgccct gagggaaaat tcgcgcccag gcaatggaaa tacgcagaca ggtgaagccc
    66901 atctcggcaa ataacgcgat atcttccggg taacggtgat aaaaatcgat ggcgacatct
    66961 ttgatattct ctttccccag gatgcgcggt tccatttttc ccattacgcc atgaggctgt
    67021 aaatctgagg tcgtgatccc tttgccatct tccagccagg caccttccac ctgattggca
    67081 gttgttgcgc caccccaaag aaatgtttct ggaaatgctt tcataattaa ctccttttat
    67141 cgttagcgaa tgatggataa cagcggctca ccagcgctta tctgcgccgt gccgtggggt
    67201 aatacgtctg taaaatcatc gctattactg attaataccg gcgtcgtcag atcaaatccg
    67261 gcctcgcgaa tagcagggat atcaaaagaa atcagccgat cgcctgtatt gaccttgtca
    67321 cccacgttga cgtgagcgga aaagaatttg ccgtccagtt ttacggtgtc gataccgaca
    67381 tgaatcagga tctccacacc atcatctgac tcaatgccaa tagcgtgtaa tgtggcgaac
    67441 aacgaagcaa ttcgacccgc aaccggagaa cgcacttcac caaccgaggg cagaatggcg
    67501 atacctttac ccaacaggcc actggcaaac gtggtatcag cgacgtgaat gagcggcaca
    67561 atctctcccg tcatcggtga acagataccg ccctgctcag gtggtgtaat aacctctggt
    67621 gttttctctt gcggggcacc ctgcgctggc tgacgtttag cggtgatgaa atgaagcatc
    67681 accgtaccga caaatgcgca accgatggca atgacaccgc caataacgct ggcccagacg
    67741 gtgaaatcaa tccccgttga cgggatggtt tgcatgaagg tgaaaatact tggcaaacca
    67801 aaggagtaaa ctttcgtttg cgcgtagcca atgatggtgg cccccaatgc tccactgata
    67861 caggcgataa cgaagggata cttacgcggc aggttgacgc catataccgc tggttcggtg
    67921 ataccaaaca ggcccgtcaa cgccgctgat cccgccacca cttttttctg cgcatcgcgt
    67981 tcgcagagga agacgccgag cgccgccccg acttgcgcca taatggcggg cattaacagc
    68041 gggatcatgg tgtcgtagcc cagcacggtg aagttattga tacacagcgg caccaggccc
    68101 cagtgcagtc cgaacatgac gaagatttgc cagaaaccgc ccattaccgc gcccgcaaat
    68161 gcaggaaccg cctgataaag ccagagataa ccggcggcaa tcatttcgct tatccaggtt
    68221 gatagcggcc ccaccagcaa aaaggtgacg ggtgtgataa ccatcagaca tagcaatggt
    68281 gtgaagaaat ttttgattgc cgacggtaac cacgcattaa gtcggcgttc cagaatgctg
    68341 cacaaccagg cagaaaaaat aatgggaata accgatgacg agtaattcaa caatgtgacc
    68401 ggaataccca ggaaatccag ccccagctca tccgcttttt gcccgttctc gaaagcagtc
    68461 agaattaatg gatgcactaa cgctccacca atcaccatgg cagtaaatgg attaccgccg
    68521 aagcgtttcc ccgcggtgta tcccaggatt atcgggaaga accaaaacaa ggcatcactg
    68581 gcgctgaata aaattaaata agtaccactt tgttcggtcg tccactgaaa agtgagcgcc
    68641 agagccagca tacctttcag gatcccggtt gccgccatca aaccgatcag aggcgtaaaa
    68701 atacctgaaa taacataaac aaagcggttt agcagattac ctttatcatc attttccggt
    68761 gcctgttgcg ctttttcgtc aaggcctgcc acactgttaa ccgccaggaa gacatcggcc
    68821 acatggttac ctatgaccac ctgaaactgg ccaccgcttt ccaccaccat aataataccg
    68881 ggggtctttt tcagtacctc tgcttgcgct ttgctttcat cctttaactt aaaacgtaat
    68941 cgcgttgcgc aatgcatcag actaacaatg ttatctgcgc ccccgactcc tgcgactatt
    69001 tttctggcta actccgtcat aacttgccct ctaccgcttt gcggcaaaac tcaaaaaaaa
    69061 aacctgaaaa aaacggcctg acgtgaatca agcaattttt tcaggttttg cccgcttagt
    69121 gcggtaacaa tcctttactc agtaataata tttcagtgtt ctttgcgcac gcgctctata
    69181 tttatggcta aaaacataat ctctgcgggt gagattttac gttgatactg caaaccaata
    69241 aaaatggcga tccgctccgc acattgccat gcttgcgggt aattttgttt tactgcttgt
    69301 tgtaatgact catcactatc gttaattgaa gcatgtccaa gaatacgcca ggataaaaac
    69361 ttcagatgcg taaccagtcg ctgataactc aagctttctt cctggtaatt aaggctgaac
    69421 tgaaatttta ttaattgcag catttcgcgc attaattgcg tgacacctgc aacatcctcc
    69481 atatttccgc tcatttgggc actgaccaga tgcatggcaa taaagcccac ttcatctttc
    69541 ggtaactgca cgcccaaccg tttatcaata atggttaacg cttcttcccc tagctggaac
    69601 tctttcgggt aaagccgctg gatatcccac agcagcgggt tgggcagtaa cacgttttgc
    69661 tgaaagcgtt taatcgcaaa ctggcaatgg tcagttagcg agatataaat actgtcctgt
    69721 aattttccca agcgctcctg cgctaaagag ataatacgat cacaggttgc catcacctca
    69781 agaggaatat gacttaagag ttcgcttaat cgcccgttca gttcatgact gctcaaggca
    69841 tactcttttt ctattccact tgagttaatt ctttcgccag cgcgtttttg aaagccaatt
    69901 ccgcgcccca tgacgacttt ttcccgctgt tgatcatcaa taaccaccac aacattattg
    69961 ttgagaattt tggtgatttg catgttcata gcaaggacct tttttataaa caaaaaaacc
    70021 cgacttcacc agtattctct ggttatgtca ggttttgcct gcgaatgcag taacaatcca
    70081 gtcatttatt aatggttttt ataacgaaca tccaggttcg gaaattaatt taattgcgtg
    70141 cagagaaaat agcaatgcgc tattgataaa aatatgacca tgctcgcagt tattaacttt
    70201 gtgtaatttt aggaatttat aaagttatat ataacaaatc ccaataatta agttattggg
    70261 atttgtctgg tgaattattt gtcgctatct ttccccgcca gcagtttatc cagctcatcg
    70321 ccaccgacgt gacggaaatc ctgccccttc acgtagtaga agataaactc acaaatattc
    70381 tggcagcggt cgccaatacg ttcgatagaa cgcgcgcaga acagcgcagt aagtacgctc
    70441 ggaatggtac gcgaatcttc catcatgtag gtcatcagtt gacgaacaat accttcgtat
    70501 tcctgatcga cttttttatc ttcacgataa atacgtaccg cttcgtcaat gtccatccgc
    70561 gcgaacgcgt ccagcacgtc gtgcagcatc tggatggtat gacggcccag cgactccaga
    70621 cttaccagca acggctgatg ctgctgggag aatttctcca gcgcagtacg gcagattttg
    70681 tccgccacgt cgccaatacg ctccagctcg gcaatggttt tactgatcac cataaccagt
    70741 cgcaggtcgc tcgccgtcgg ctgacgtttg gcgataatgc gcacgcaggc ttcatcgatc
    70801 gccacttcca tcatgttgac gttcttgtcg ccttcgatca cgcgcttcgc cagatcgctg
    70861 tcctggttat gcatcgcggt gattgcatca gaaagctgct gctccaccat gccgcccatg
    70921 gtcatcacct gcgtgcggat actttccagt tcggcgttga actggccgga aatatgttta
    70981 ttaagattga gactgtccat aacgcactcc tgaatcaacc gtaacgaccg gtgatgtagt
    71041 cttctgtttg tttcttcgct ggcttggtga acagatcgtc cgtgttgctg aactcaatca
    71101 attcgcccag gtacataaac gccgtgtggt cggaacaacg cgcagcctgc tgcatgttgt
    71161 gggtgacgat caccacggtg taatcctgct tcagttcggt gatcagctct tcaatacgcc
    71221 cggtagagat agggtcgagc gccgaacacg gttcgtcgag cagcagcact tccgggcgaa
    71281 tggcgatacc acgcgcaata cacagacgct gttgctgacc accagagaga gagtaaccgc
    71341 tctggtgcaa tttatctttg gtttcgttcc acaatgcggc tttggtcaat gcccactgca
    71401 cgcgctcgtc catgtcggca cgggagagct tctcaaacag acgaacgcca aaagcgatgt
    71461 tgtcgtagat ggacatcgga aacggcgtcg gtttctggaa caccatgccc actttcgcac
    71521 gcagcagggc gatatcctga gagttggtca ggatgttgtc gccatcaagc agaatttcac
    71581 cttctgcgcg ctgctccgga tacagttcaa acattttgtt gaaggtacgc agcagcgtcg
    71641 atttaccgca gccggacggc ccgataaacg ccgttacctg gtttttagcg atatccaggt
    71701 tgatgttttt cagggcatgg aatttgccgt agtagaagtt caaattacga acctgaattt
    71761 tactcggggc agtttcaacc atactcattg caatcttttc ctcatcgtac ctgatgcttt
    71821 tcgctaatca ggcttaccgt aggccgggta aggcgttcac gccgcatccg gcaaagtgtt
    71881 aaccgtgttt attcttcgca aaaacaacgc gcgccagaat gttcagcagc aggacgcaca
    71941 gggtaatgat caataccccg gcccaggcca gttgttgcca ttccgcaaac gggctcatcg
    72001 caaacttaaa gatcgtcacc ggcaggttgg cgatcggctg catcatgtcc gtgctccaga
    72061 actggttgga gagcgcggta aacagcagcg gcgcggtttc accggcaata cgggcaatcg
    72121 ccagcaggat accggtcata atcccggaca ccgacgcttt cagcgtaatc gcggagatca
    72181 tcttccactt cggtgtaccc agcgcataag ccgcttcacg caggctgtcc ggcaccagtt
    72241 tcagcatgtt ctcggtggtg cggataacga tcggcacctg caacagcgcc agcgcaatta
    72301 cgcccgccca gccggagaag tgctccatct gtgccaccac gatggtgtag acaaacagac
    72361 caaccacaat cgacggcgcg gagagcagaa tgtcgttaat gaagcgaatc acttctgcca
    72421 gccaggattt acgaccatat tccgccagat aaatccccgc cataatgccc agcggcgtac
    72481 cgaataccgt ggcccacaaa attaacagcc cgctacccgc cagggcgttc gccagaccac
    72541 caccttccgt attgggcggc ggcgtcattt cagtgaacag cgccagcgac ataccgtcga
    72601 taccgcgagt gatggtggac attaaaatcc agatcagcca gaacaggccg aaggccatcg
    72661 tcgccatcga gagcgtcagc gcaatacggt ttttgaggcg gcgacgcgcc tgcattttgc
    72721 ggcgagattc agccagcgcc gcagtggttt gcatttcaac catagccatt agcgtgcccc
    72781 ctcattctta gccaggcgca taatcataaa cttcgatgcg gcgaggacga tgaaggtaat
    72841 cacaaacagg atcaggccca gttccatcag tgcggcaacg tgcagaccgg attccgcttc
    72901 cgcaaattcg ttcgccagcg cagaggtgat actgttgccc ggcatataca gcgaggcgct
    72961 gtcgagctgg taggtgttac cgatgataaa ggtcaccgcc atggtttcac cgagcgcgcg
    73021 gcccagcccc agcatgatgc cgccgataac accatttttg gtgaacggaa gaacgatacg
    73081 ccagataact tcccaggtgg tgcagccaat accgtaggcc gactctttca tcatcaccgg
    73141 ggtttgttcg aacacatcac gcattaccgc cgcaatgtac ggaataatca tgatggcgag
    73201 gatcacgcct gccgcgagga taccgatacc aaatgcgggg ccagagaaca gcgcgccaac
    73261 aatcgggata ttcgacatga tattgccgac cggctcctgg aagtaaacgg cgaatagcgg
    73321 cgcaaagata aacaggcccc acatgccgta aacgatactt ggaatggctg ccagcagctc
    73381 aatggcgata cccagcgggc gtttcagcca gccaggcgca agctcagtca ggaacagggc
    73441 gataccgaaa ctcaccggga cggcgatcag cagcgcgata aacgaagtca ccagcgtacc
    73501 gtagatcggc actagcgccc cgtagatatc gttcggtgca tcccactctt tggtccagag
    73561 gaaagccaga ccaaatttct gaatgctcgg ccaggaggag atgatcagag agacaataat
    73621 gccacccaac atcaatagca caatcagcgc cgccagtttt accagcacgc tgaaaattat
    73681 gtcgcccttt ttacccggtg ggttaaaagc aggcttggtt gcagccataa gttactcttc
    73741 agttaaacgc gtttacaaag tcattttgta atgccggata agccgttaat gccttatccg
    73801 gcctggagtt ttattagtac agcggcttac cgctactgtc tttaatattg gtcttccacg
    73861 cagcgcgaac ctgttcaact acactatccg gcaggctggc gtaatccagg tcgttcgcct
    73921 gtttagcacc ggttttgtac gcccagtcga agaatttcag cacttctgtg ccttgttctg
    73981 gtttcttctg atctttgtgg atcagaatga acgtggtaga ggtaataggc cacgcatctt
    74041 cgcctttctg gttggtcaga tcctgagcga aggttttgct ccagtctgcg ccttttgctg
    74101 cattagcgaa gttttcttcg gtcggactaa ccggtttacc atcagcggag atcagtttgg
    74161 tatacgccag gttgttctgc ttcgcgtaag catattcaac gtaaccaatt gcacccggca
    74221 gacgctgaac gaacgcggcg ataccgtcat tacctttacc gcccagaccg atcggccatt
    74281 ttacggtaga gccagtacca acgttgtttt tccactcttc gttcactttc gccagatagc
    74341 tggtgaagac gaaggaggta ccggagccat ctgcgcggcg taccacggcg atgttctgtg
    74401 acggcagttt cagacccgga ttcagtttgg cgatggcttc atcatcccac ttcttgattt
    74461 tgccgaggta gatgtcgccg agggttttac catccagcac cagttcgcca gacttcagcc
    74521 ctggaatgtt aacagccagc accacgccgc caatcacggt cgggaactgg aacagacctt
    74581 cctgagccag tttttcgtca gacagcggcg cgtcagaggc accaaaatca acggtattag
    74641 cgataatctg ttttacgcca ccggaagaac cgataccctg gtagttaact ttattaccgg
    74701 tttctttctg gtaagtgtca gcccatttgg catacaccgg cgcagggaag gttgcacctg
    74761 cacctgtcag gcttgcttct gcaaacacag agaaagcgct catcgataag gtcgcggcga
    74821 caacagttgc gacggtggta cgcataactt tcataatgtc tcctgggagg attcataaag
    74881 cattgtttgt tggctacgag aagcaaaata ggacaaacag gtgacagtta tatgtaagga
    74941 atatgacagt tttatgacag agagataaag tcttcagtct gatttaaata agcgttgata
    75001 ttcagtcaat tacaaacatt aataacgaag agatgacaga aaaattttca ttctgtgaca
    75061 gagaaaaagt agccgaagat gacggtttgt cacatggagt tggcaggatg tttgattaaa
    75121 aacataacag gaagaaaaat gccccgctta cgcagggcat ccatttatta ctcaaccgta
    75181 accgattttg ccaggttacg cggctggtca acgtcggtgc ctttgatcag cgcgacatgg
    75241 taagccagca gctgcagcgg aacggtgtag aagatcggtg caatcacctc ttccacatgc
    75301 ggcatctcga tgatgtgcat gttatcgcta cttacaaaac ccgcatcctg atcggcgaag
    75361 acatacaact gaccgccacg cgcgcgaact tcttcaatgt tggatttcag tttttccaac
    75421 agttcgttgt tcggtgcaac gacgataacc ggcatatccg cgtcaatcag cgccagcggg
    75481 ccgtgtttca gctcgcctgc agcgtaggct tcagcgtgaa tgtaagagat ctctttcagt
    75541 ttcaatgcgc cttccagcgc gattgggtac tgatcgccac ggcccaggaa cagcgcgtga
    75601 tgtttgtcag agaaatcttc tgccagagct tcaatgcgtt tgtcctgaga cagcatctgc
    75661 tcaatacggc tcggcagcgc ctgcagacca tgcacgatgt catgttcaat ggaggcatcc
    75721 agacctttca ggcgagacag cttcgccacc agcatcaaca gcacagttaa ctgagtggtg
    75781 aatgctttag tggatgccac gccgatttcc gtacccgcgt tggtcatcag cgccagatcg
    75841 gattcgcgca ccagagaaga acccggaacg ttacagattg ccagcgaacc aaggtaaccc
    75901 agctctttcg acagacgcag gcccgccagg gtatccgcgg tttcgccaga ctgtgacaag
    75961 gtgatcatca ggctgttacg acgcacggca gatttgcgat agcggaattc agaggcgatt
    76021 tcgacgtcgc acggaatacc tgccagcgat tcaaaccagt aacgggaaac cataccggag
    76081 ttataagaag taccacaggc gaggatctga atatgctcaa ccttcgacag cagttcgtcg
    76141 gcgttcggtc ccagctcgct taaatcaacc tgaccgtggc tgatgcgccc ggtaagggtg
    76201 tttttgatcg cgttcggctg ttcgtagatc tctttctgca tgtagtgacg gtaaatacct
    76261 ttatcgcccg cgtcatattg cagattggat tcgatatcct gacgttttac ttccgcgcca
    76321 gttttatcga agatgtttac cgaacggcga gtaatttccg caatatcgcc ctcttcaagg
    76381 aagataaagc gacgggtcac cggcaacagc gccagctggt cagaagcgat aaagttttcg
    76441 cccataccca ggccaatcac cagcggacta ccagaacgtg ccgccagcag ggtatccggg
    76501 tgacgggagt ccatgatcac tgtaccgtac gcaccacgca gttgcgggat agcacgcaga
    76561 acagcctcac gcagagtacc gccctgtttc agctcccagt tcaccagatg ggcaattact
    76621 tcggtgtctg tttcagaaac gaaggtatag ccacgcgctt ttaactcttc gcgcagcggt
    76681 tcatggtttt cgatgatgcc gttatgcacc accacaatgt gttcagaaac atgcggatgc
    76741 gcattcactt ctgaaggttc accgtgggtc gcccagcgag tatgagcaat acccgtaccg
    76801 ccatgcagag gatgttcttc cgctgcctga gccagcatct ggactttacc gaggcgacgc
    76861 aggcgggtca tatgaccttc cgcatcaaca acggccagac cggcagagtc atatccgcgg
    76921 tattccagac gacgtaaacc ttcaagaagg atttctgcta catcacgttg cgcgatcgcg
    76981 ccaacaattc cacacatagt ttttgattcc gatttatatc gttgtcggtc aacctgtatg
    77041 cccgtttttt cgggcgcccc gagccttgta gagagtgggg ttatttttat agttactgct
    77101 tgtgggaggg agattatgtt atctcctcat cccatgtgac cggattaccc ggccagaatc
    77161 actttttctt taccggacga cgccagcctt ctttctgagt ctgcggcaca cggctgatag
    77221 ctaatgcatt ttcgccgaca ttacgcgtca cagttgtacc cgcagcaatg gtcgcgcctt
    77281 tgcctactgt taccggggcc accagctgag tgtcggaacc gacaaacaca tcgtcgccga
    77341 taatggtctt aaatttattc gcaccatcgt agttgcaggt aatggttccc gcgccgatgt
    77401 taacgttatc gccaatttcc gcatcgccca ggtaagtcag atgaccagct ttcgagcctt
    77461 tacccagacg cgcttttttc atctcaacaa agttaccgac gtgtgcacct tccagcaact
    77521 cagcaccagg acgcagtcgg gcaaacgggc caatagtaca ggccgctgcc agattcgcgt
    77581 cttccacaac ggtatacgga ctgatttcgc aatcatcgcc aatcacgctg tttttaatca
    77641 cgcaaccggt gccgattttc acgcgatgac cgagagtcac gttgccctcg atgataacgt
    77701 tagtatcaat ttcaacatcg cgcccgtgag taagcgtacc gcgcaaatca aaacgcgccg
    77761 gatcgcgcag cataacgcct gctaacagca gtttttcagc ctgttcggac tggtaaacgc
    77821 gctccagacg ggagagttgc aggcggttat tcacaccttc tacttcgctt aaacgttgcg
    77881 gatgaacggc gacgatttca cgcccttcct gatacgccag cgcaataatg tcggtgatgt
    77941 agtattcgcc ctgagcatta ttgttggtca gcttcgccag ccagcgtttc atatctgcgc
    78001 cgttagcgat cagaatgccg gtgttgatct cctgaatctg acgctgctcg tcggtggcat
    78061 ctttgtgctc aacaatgccg gtaactttgc cattttcacg ggtgatacgt ccataaccgg
    78121 tcggatcatc cagtttcacc gtcagcagac caatgccacc ctgcggttta gcatcacgca
    78181 ggcgctggag tgtttcgaca gagatcagcg gcacgtcgcc gtagagcatt aaaatgtctt
    78241 catcatcggc aaagaaaggt gcggcctgct gcattgcatg acccgtaccc agctgctctg
    78301 cctgaagcac ccagttaagg ttgtcgtctt tcagcgcctg tttaagcaga tcgccgccgt
    78361 gaccgtacac caggtgaacg tgcgctgcgc ctaattcatt cgcagcatca atgacatgct
    78421 gaaccatcgc tttcccggca agggtatgca gcactttcgg aagatcggaa tacatgcgcg
    78481 tgcctttgcc tgcggcaagg atcactacgc tcatagcatt attcaacata cgcgtcctga
    78541 ctgtaatttg agaacgaatt taaaccgctt caccttgaaa aaactacatt tttttcatcg
    78601 tgaaatggac agaggataaa ttgttcaata acggattatc cccgctgacg aaagtgccat
    78661 tttcgaccat cgtcacgcct tttgtctgca gaaaattaag gcagtacctt catttaagcg
    78721 tcaggtggat gtttttgctc ttatttcgat caatgaataa acgggaaaac aggggtgttt
    78781 tatatcagca ggatctatgt gaacgctctt caggacggat cacgcgtaaa aaaaagccag
    78841 cctgtttcca gactggcttt tgtgcttttc aagccggtgt tacatcgctt ttttggtcaa
    78901 ctcgataacg cgcagctgcg cgatcgcttt ggccagttcc gcagacgcct gagcgtaatc
    78961 tacgtcgccg tgagagctgc taatgtgctc ttcagcctta cgtttcgctt ccatggctcg
    79021 cgcttcgtcg agatcctggc cgcgaattgc ggtgtcggcc agaacggtca cgttgccagg
    79081 ctgcacttca agaatgccgc cagacagata gataaactct tcgtgaccgt gctgtttcac
    79141 gatgcgaatc ataccaggct taatggcggt gagcagcggt gcgtggccag ggtagatccc
    79201 cagttcacct tcgctacccg ttacctggat tttctcgacc agaccagaga acatttgttg
    79261 ctctgcgctg acgacgtcca ggtggtaagt cattgccata tcaccctccg attaaggcgt
    79321 taaagttttt tggctttttc cacagcttct tcgatggaac cgaccatgta gaacgcctgc
    79381 tccggcaggt gatcgtattc gccttccatg atgcctttaa agccacggat ggtgtctttc
    79441 agggagacgt atttacccgg agaaccggtg aatacttctg ccacgaagaa cggctgggac
    79501 aggaagcgct ggatcttacg agcacgcgct accaccagtt tgtcttcttc agacagttca
    79561 tccataccca ggatggcgat gatgtctttc agttcctgat aacgttgcag gatggactga
    79621 acgccacgcg cggtgtcgta gtgttcctga ccaaccacca gcgggtccag ctgacggctg
    79681 gtggagtcca gcgggtcaac ggccgggtag atacccagag acgcgatctg acggctcagt
    79741 accacggttg cgtcaaggtg cgcaaaggtg gttgccggag acgggtcagt caagtcatcc
    79801 gcaggtacgt atactgcctg tacggaggtg atagaaccag ttttggtgga ggtgatacgt
    79861 tcctgcagaa cgcccatctc ttccgccagg gtcggctgat aacctaccgc tgaaggcata
    79921 cggcccagca gtgcggatac ttccgtacct gccagggtgt aacgatagat gttgtcaacg
    79981 aacagcagaa cgtcacgacc ttcgtcacgg aatttctcag ccatggtcag accggtcaga
    80041 gcaacgcgca gacggtttcc cggcggctcg ttcatctggc catacaccag ggatactttg
    80101 tcgataacgt tggagtcggt catttcgtgg tagaagtcgt taccctcacg agtacgttca
    80161 cctacgcccg caaacacaga gtaaccggag tgctcgatcg cgatgttacg aatgagctcc
    80221 atcatgttta cggttttacc tacacccgca ccaccgaaca gaccaacttt accgccctta
    80281 gcgaacggac acatcaggtc gataactttg ataccggttt ccagcagttc ctgagagttt
    80341 gacagctctt cgtaggaagg tgctgcgcgg tgaatcgccc aacgctcttc ttcaccgatc
    80401 tcgcctttca tgtcgaccgg ttcacccagt acgttcatga tacggcccag agtcgcttta
    80461 cctaccggga cttcgatcgg gtgttcgagg tcttttacat ccagaccgcg acgcagaccg
    80521 tcggaggaac ccattgcgat ggtacgcacg ataccgccgc cgagctgctg ctgaacttcc
    80581 agcaccagac gctcattacc attttgcacc tcaagagcat cgtacacgcg cggtacggca
    80641 tcctgaggga attcgacgtc aactacggcg ccgattacct ggacaatctt tccagtagcc
    80701 atcttaaatc ctctacgaaa taacctgttt aaaccgcggc ggcccccgag acgatctcgg
    80761 tgagttcctg agtaatgctg gcctgacgag ctttgttgta taccaactgc agctctttaa
    80821 tcaggctgcc gccattgtcg gtcgcggctt tcatcgccac catacgggcg gcctgctcgc
    80881 tggccaggtt ttcaaccacg ccctgataaa cctgagattc gacataacga cgcagcaggg
    80941 tatccagcaa cgccttcgga tcgggttcgt acaggtaatc ccaggattta tgtttcagat
    81001 catcatcatc tgatgccggt aacggcagca gctggctgat ggtcggaacc tgagacatgg
    81061 tgttaataaa tttgttgctg acaatgtaaa gcttgtccag acggccttcg tcgtaggcct
    81121 gcaacatcac ttttaccgga ccgatcagtt cggacaggga agggttatcc cccatgccgg
    81181 tgacctgggc aacaacattg ccgcccacgg agttgaagaa cgacacgcct ttcgagccga
    81241 tcattgcgag gtcgcattga acgcctttgt cggtccaggt cttcatttcc gccagcagtt
    81301 ttttgaacag gttaatgttc aaaccaccgc acaaaccacg gtcggtcgac accaccaggt
    81361 agcccacgcg tttaacgtcg cggtcttcca ggtaagggtg cttatattcc agattaccgt
    81421 gtgcaaggtg accaatcact ttgcgcatgg tttctgcata aggacggctg gccgccatgc
    81481 gatcctgcga tttacgcatt ttggaagcgg cgaccatctc catcgcttta gtgatctttt
    81541 gcgtgttctg gacgcttgcg atcttactac gtatctcttt tgcgccggcc atgagcttct
    81601 cctcaatgcc ttgcggcctg ccctaaggca agccgccaga cgttaccagg attgggttgc
    81661 tttgaaggaa tcgaggatgc ctttcagctt gccttcgatt tcgtcgttgt agccaccggt
    81721 ctggttgatc tcttgcatca acggagcgtg atcacggtcg acgtaagcca gcagagcggc
    81781 ttcgaagctg ccaattttcg acagttcaac atccgccagg taaccacgtt ctgctgcgaa
    81841 cagaaccaga gactgctgcg caacggacat cggcgcatac tgtttctgtt tcagcagttc
    81901 ggtcactttc tgaccgtggt caagctgctt acgtgttgca tcgtcaaggt cggatgcaaa
    81961 ctgagagaac gctgccagtt cacgatactg tgccagagcg gtacggatac caccggacag
    82021 ttttttcatg atcttggtct gtgctgcacc accaacacgg gatacggaaa tacccgggtt
    82081 aaccgcagga cgaataccgg cgttgaacag gttggtttcc aggaagatct gaccatcggt
    82141 aatggagatt acgttggtcg gaacgaacgc agaaacgtca cccgcctgag tttcgataat
    82201 cggcagtgcg gtcagagaac cggttttccc tttcacttca cctttggtga aggcttcaac
    82261 gtattcggcg ttaacacgtg cagcacgctc cagcagacga gagtggaggt agaaaacgtc
    82321 gcccgggaat gcttcacgtc ctggcggacg acggagcagc agggagatct gacggtaagc
    82381 aacagcctgt ttagacaggt catcgtaaat gatcagcgca tcttcaccgc ggtcacggaa
    82441 gtattcgccc attgcgcaac cggcatacgg tgccaggtat tgcagtgcag cggattcaga
    82501 cgcggttgct accacaacga tggtgttagc cagtgcgccg tgctcttcca gtttacgtac
    82561 cacgttagaa atggtggacg ctttctggcc gatagcgaca tagatacatt tgataccgga
    82621 atcgcgctgg ttgatgatgg catcgatagc cagtgcggtt ttacctgtct gacggtcacc
    82681 gatgatcaat tcacgctgac cacgaccgat tgggatcatg gagtcaacgg ctttataacc
    82741 ggtctgtacc ggctgatcta cggactgacg ttcgataacg cccggagcga ttgcttctac
    82801 agcagagaag ccgtcgtgat ccagcggacc tttaccgtcg attggtgcac ccagagtgtt
    82861 aaccacacgg cccagcaggc cacggccaac cggaacttcc aggatacggc cagtacactt
    82921 aactttcatg ccttcggcaa ggtcagcgta cggacccata acaaccgcac ctacagagtc
    82981 gcgctcgagg ttcagtgcga tagcgtaacg gttacccggc agggagatca tttcaccctg
    83041 catacaatcg gccaggccgt gaatgcggat aacaccgtca cttacagaaa caatagtacc
    83101 ttcgttgtga gcttcactca caacattgaa ctgagcaatg cgctgcttga tcagttcgct
    83161 gatttcggtg gaattcagtt gcatgctcca gtccccttaa gactgcaaga cgtctgcaag
    83221 gcgctcaaga cgaccgcgta cgctgccatc aatgaccata tcacccgctc ggatgataac
    83281 gcctgccatt acagacttat cgattttgca attcagctta actttgcgtg acagacgttt
    83341 ttccatcgca gcagaaattt tcgcgagctg ttgttcactc agtgcggcag cggaaatgac
    83401 gtctacctca gcggtagcct cactcacggc acgaaggtga ataaactgct ccagaacatc
    83461 cgggagcgcg ttaagacgac cattttcagc cattacccga atcaggttct gaccgttttc
    83521 gtccagttgc tcaccacaaa ctgcgataaa cgactcggcg agcgtttctg gcgcaagcgc
    83581 gccagagaga agctctgcca tttgttcgtt tttggttacc tcggcggcaa acgccagcat
    83641 gtcctgccag cgttctacac tttggtgttc gacggcaaag tcaaaagctg ctttggcgta
    83701 ggggcgagct accgtaataa attcagacat cagcccctcc ctccttacag ttcagcgaca
    83761 agtttatcca cgatgtcgct gttagcagct tcatccacgg aacgttcgat gatcttctcg
    83821 gcgccagcaa cagccaggat agcaacttgc ttacgcagct cttcacgggc acgtttacgc
    83881 tcggcttcaa tttctgcctg cgcctgggcc acgattttag tacgttcctg ttctgcctca
    83941 gctttcgctt cgtccagaat ctgcgagcgg cgtttgttcg cctgctcgat gattacctgg
    84001 gcttccgctt tcgctttttt cagctggtcg gtcgcgctgg cctttgcaag gtcaaggtcc
    84061 ttatgtgctc gttctgcgga agcaaggccg tcagcaattt ctttttgacg tttttcgatg
    84121 gctgccatta atggcggcca tacgtacttc atgcagaaca gaacgaacag gacaaacgcg
    84181 atggcctggc cgaggattgt tgcgttaaga ttcacagcac aatgcctcta tttagttaac
    84241 gttctgatat tgctctttaa ataaaagcaa cgcttactac gcgacagcga acatcacgta
    84301 cagacccaga cctacagcga tcatcgggat agcatccacc agacccataa cgataaagaa
    84361 ctgagtacgc agcagaggaa tcagatcagg ttgacgcgct gcgccttcca ggaatttacc
    84421 cccgaggatg ccgataccga tcgcagcacc gattgccgcc agacccatca tcacagcggc
    84481 agccatgtac agcagatcca tattcaggtt ttccatgaca gtctccagtt tgtttcagtt
    84541 aaaacgtagt agtgttggta aattaatgtt cttcagacgc catcgacaga tagacgatcg
    84601 tcagaaccat gaagatgaag gcttgcagcg taatgatcag gatgtggaaa atggcccacg
    84661 gcacattcag gatccactgt gaccaccacg gcaacagacc agcaatcaga atgaaaatca
    84721 gctcaccggc atacatgtta ccgaacagtc gcaaaccaag tgaaactggt ttggacagca
    84781 ggcttacccc ttcaaggatt aagttgacag gaatgaacgc ccagtgattg aacggctgca
    84841 gcgtcaactc tttcgtgaag ccgccgatgc ctttcatttt gatgctgtag aacagaatca
    84901 ggataaatac gcccaatgcc atagacagcg ttacgttcac gtccgcagac ggaaccacac
    84961 gcagtgcagg cagacccagt acatgttcag caatgtacgg cagcaggtcg ataggcagta
    85021 aatccatcag gttcatcagg aatacccaga cgaagatcgt cagggccagc ggagcaatca
    85081 gcttgctttt gccatggtac atgtctttca cgctaccatt aacaaagccg atcaccagct
    85141 caatcgcggt ctgaaactta cctggcacac cgctggtcgc ctttttggct acgctacgga
    85201 ataaaaccag gaacaacaga cccagcacca ccgagaagaa catggagtca atattgattg
    85261 tccagaaggt ggctgggggg ttttgtggat ccaccagcga gaatgtacgc aggtccagct
    85321 gaaggttatt caggtggtgt cctatgtaat cctgcggcgt catattttct gaagccatga
    85381 tgccttttac cctttgttgt taattacagc cggtgccagt atctgaacca ccagcaccaa
    85441 aacccacgta acgatcagcg gcaagaatac cgcctttaaa accgccaacg ccaccaccag
    85501 taacaccaac atcgccagaa ctttgaaagc ttcgccaaat gcgaatgtcc aggccacccg
    85561 gcctttcgct ggtgtatgcg cctggtgacg ccaggcaaat atcataaaca aaacgttagg
    85621 cagaaagact gccaggcccc cgcttattgc agagacgccc cagaaggggt ctttgaggct
    85681 gaacagcaat ccacttgcta tcaccaccag taactgaacg agcagaagct tccgagcaac
    85741 gtttcgactc acgagcgaca cagacatcac gtttttcact cctgctccct tcgaggtatg
    85801 ccgcgtgtcg tataaaactt tctttaaggc ttagagtcaa gcatcaaaaa gcggtcaaat
    85861 tatacggtgc gcccccgtga tttcaaacaa taagtagcca aaaggtgaat aaatgtttaa
    85921 atatttttcc agtgcataca attgcgactt ttctgctaac cctgttcgat catgaaaaac
    85981 tgtaaataac gcgtaaacac tggtgataaa gcgtgcttca gatcacatat tgcgcatgtt
    86041 cgcgcacagc atatttattt acttggcaaa tgatgccttt gcaagtttat gatatttaag
    86101 tctaaaaaca gatactgttt taataaatga catttacaca acaaaaacca cccattgaca
    86161 tttttaataa tgttttaaca gccaatgatg attcttagcg ccgattttta gcagactgat
    86221 attttcacta atgacttatt ttctgcttac caaaaaaagc cacgttatct tgttgatgca
    86281 aaagagtgaa cgtggcgtta aatgtaacca gttatatcag
//
LOCUS       DAZUDJ010000012        76833 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.012, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000012 DAZUDJ010000000
VERSION     DAZUDJ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 76833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76833
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.012"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            337..597
                     /locus_tag="ACHY1N_001216"
     CDS             337..597
                     /locus_tag="ACHY1N_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001512982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HFS4043556.1"
                     /translation="MFRCPLCRASARIRTSRPENDSNTVRQKYYQCNNLECGVCFSTL
                     EAFHKFTSKHASGVHSSEGIPWHELPASHRGNNQMSLPLPQN"
     gene            788..928
                     /locus_tag="ACHY1N_001217"
     CDS             788..928
                     /locus_tag="ACHY1N_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HFS4043557.1"
                     /translation="MSQKSLTAITFCVTAILIIWMLHGSLCEIRMSFWGAEFAAFLQC
                     KQ"
     gene            complement(1235..1534)
                     /gene="ihfA"
                     /locus_tag="ACHY1N_001218"
     CDS             complement(1235..1534)
                     /gene="ihfA"
                     /locus_tag="ACHY1N_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HFS4043558.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE"
     gene            complement(1539..3926)
                     /gene="pheT"
                     /locus_tag="ACHY1N_001219"
     CDS             complement(1539..3926)
                     /gene="pheT"
                     /locus_tag="ACHY1N_001219"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFS4043559.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHG
                     VVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLRVAVATIGAVLPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPIGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNQLPLVEPEIVPVGATIDDTLPITVEAPEACPRYLG
                     RVVKGINVKAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGI
                     VVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGEHSGVNDETQNVLLE
                     CAFFSPLSITGRARRHSLHTDASHRYERGVDPALQHKAMERATRLLIDICGGEAGPVI
                     DITNEATLPKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPS
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPVQASLIMGTHREADLSLKRVKTLLNDKGYQ
                     EVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNR
                     VRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESV
                     LDLTGKLNEVEFRAEANPALHPGQSAAIYLKGKRIGFVGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            complement(3941..4924)
                     /gene="pheS"
                     /locus_tag="ACHY1N_001220"
     CDS             complement(3941..4924)
                     /gene="pheS"
                     /locus_tag="ACHY1N_001220"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFS4043560.1"
                     /translation="MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK"
     misc_feature    complement(5134..5258)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            complement(5208..5252)
                     /gene="pheM"
                     /locus_tag="ACHY1N_001221"
     CDS             complement(5208..5252)
                     /gene="pheM"
                     /locus_tag="ACHY1N_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pheST operon leader peptide PheM"
                     /protein_id="HFS4043561.1"
                     /translation="MNAAIFRFFFYFST"
     gene            complement(5375..5731)
                     /gene="rplT"
                     /locus_tag="ACHY1N_001222"
     CDS             complement(5375..5731)
                     /gene="rplT"
                     /locus_tag="ACHY1N_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFS4043562.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
     gene            complement(5784..5981)
                     /gene="rpmI"
                     /locus_tag="ACHY1N_001223"
     CDS             complement(5784..5981)
                     /gene="rpmI"
                     /locus_tag="ACHY1N_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFS4043563.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            complement(6078..6620)
                     /gene="infC"
                     /locus_tag="ACHY1N_001224"
     CDS             complement(6078..6620)
                     /gene="infC"
                     /locus_tag="ACHY1N_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFS4043564.1"
                     /translation="MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            complement(6624..8552)
                     /gene="thrS"
                     /locus_tag="ACHY1N_001225"
     CDS             complement(6624..8552)
                     /gene="thrS"
                     /locus_tag="ACHY1N_001225"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFS4043565.1"
                     /translation="MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGEL
                     VDACDLIENDAQLSIITAKDEDGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSIL
                     DENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEMFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEV
                     IEKLQQEIRSRSLKQLEE"
     gene            9076..10974
                     /gene="espL1"
                     /locus_tag="ACHY1N_001226"
                     /pseudo
     CDS             9076..10974
                     /gene="espL1"
                     /locus_tag="ACHY1N_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector EspL1"
     gene            11150..11257
                     /gene="yniD"
                     /locus_tag="ACHY1N_001227"
     CDS             11150..11257
                     /gene="yniD"
                     /locus_tag="ACHY1N_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small membrane protein YniD"
                     /protein_id="HFS4043566.1"
                     /translation="MPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG"
     gene            complement(11310..12068)
                     /gene="ydiY"
                     /locus_tag="ACHY1N_001228"
     CDS             complement(11310..12068)
                     /gene="ydiY"
                     /locus_tag="ACHY1N_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HFS4043567.1"
                     /translation="MKLLKTVPAIVMLAGGMFASLNAAADDSVFTVMDDPASAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTTMTWYGQTTAWSLWGNASNTSSNDERSSEKYAAGG
                     RSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DKYTDNASETQPLGYASGAYAWQLTDNAKFTQGVSVFGAEDTTLNSESALNVAINEHF
                     GLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM"
     gene            12355..13284
                     /gene="pfkB"
                     /locus_tag="ACHY1N_001229"
     CDS             12355..13284
                     /gene="pfkB"
                     /locus_tag="ACHY1N_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707391.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HFS4043568.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINV
                     ARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGE
                     QYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQNQG
                     IRCIIDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKA
                     KRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR"
     gene            13385..13675
                     /gene="ghoS"
                     /locus_tag="ACHY1N_001230"
     CDS             13385..13675
                     /gene="ghoS"
                     /locus_tag="ACHY1N_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HFS4043569.1"
                     /translation="MASGDLVRYVITVMLHEDTLTEINELNNYLTRDGFLLTMTDDEG
                     NIHELGTNTFGLISTQSEEEIRELVSGLTQSATGKDPEITITTWEEWNSNRK"
     gene            13781..14641
                     /gene="yniA"
                     /locus_tag="ACHY1N_001231"
     CDS             13781..14641
                     /gene="yniA"
                     /locus_tag="ACHY1N_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFS4043570.1"
                     /translation="MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFV
                     KCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHS
                     AFILGQQIARLHQWSDQPQFGLDFDNSLSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTEQPPQIYDGYQSVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIA
                     QQSLDRLLAA"
     gene            complement(14682..15218)
                     /gene="yniB"
                     /locus_tag="ACHY1N_001232"
     CDS             complement(14682..15218)
                     /gene="yniB"
                     /locus_tag="ACHY1N_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YniB family protein"
                     /protein_id="HFS4043571.1"
                     /translation="MTYQQAGRIAVLKRILGWVIFIPALISTLISLLKFMNTRQENQE
                     GINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNFNGGVNVMFWVIFILIFVGLALQ
                     DSGARMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYIL
                     PVICIAAGYVFFSLLGFI"
     gene            15365..16033
                     /gene="hxpB"
                     /locus_tag="ACHY1N_001233"
     CDS             15365..16033
                     /gene="hxpB"
                     /locus_tag="ACHY1N_001233"
                     /EC_number="3.1.3.22"
                     /EC_number="3.1.3.50"
                     /EC_number="3.1.3.68"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HFS4043572.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRN
                     ELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVERVIARAISLVEETRPLLPGVREAVA
                     LCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLANVKLSSLTELTAK
                     DLLG"
     gene            16196..16786
                     /gene="ydjM"
                     /locus_tag="ACHY1N_001234"
     CDS             16196..16786
                     /gene="ydjM"
                     /locus_tag="ACHY1N_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707386.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFS4043573.1"
                     /translation="MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAILTCLL
                     PDIDHPKSFLGQRLKWISKPIARAFGHRGFTHSLLAVFALLATFYLKVPEGWFIPADA
                     LQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRLPILVPQKGNQLERFICMALFVWSV
                     WMPHSLPENSAVRWSSQMINTLQIQFHRLIKHQVEY"
     gene            16919..18310
                     /gene="tcyP"
                     /locus_tag="ACHY1N_001235"
     CDS             16919..18310
                     /gene="tcyP"
                     /locus_tag="ACHY1N_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine/sulfocysteine:cation symporter"
                     /protein_id="HFS4043574.1"
                     /translation="MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
                     LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLAA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFA
                     VHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKA
                     ILDSEDDAELAHR"
     gene            complement(18314..19117)
                     /locus_tag="ACHY1N_001236"
                     /pseudo
     CDS             complement(18314..19117)
                     /locus_tag="ACHY1N_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416244.2"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(19406..19669)
                     /gene="cedA"
                     /locus_tag="ACHY1N_001237"
     CDS             complement(19406..19669)
                     /gene="cedA"
                     /locus_tag="ACHY1N_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HFS4043575.1"
                     /translation="MRLVKPVMKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVW
                     MLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQEGEVTE"
     gene            19852..22113
                     /gene="katE"
                     /locus_tag="ACHY1N_001238"
     CDS             19852..22113
                     /gene="katE"
                     /locus_tag="ACHY1N_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004096 - catalase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HFS4043576.1"
                     /translation="MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTP
                     PGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGNRGP
                     TLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKIT
                     PVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFV
                     HAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHT
                     FRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEY
                     ELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFH
                     PGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHR
                     MGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHP
                     RLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIEL
                     TDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALK
                     AKGVHAKLLYSRMGEVTADDSTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDAN
                     YYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIVEADSADGSFMDELLTLMAAHR
                     VWSRIPKIDKIPA"
     gene            complement(22160..22918)
                     /gene="chbG"
                     /locus_tag="ACHY1N_001239"
     CDS             complement(22160..22918)
                     /gene="chbG"
                     /locus_tag="ACHY1N_001239"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HFS4043577.1"
                     /translation="MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAID
                     HAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQ
                     ELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRIDRQPLSNAG
                     DLPANLRSSQGFSSAFYGEEISEALFLQVLDDASHRGDRSLEVMCHPAFIDNTIRQSA
                     YCFPRLTELEVLTSASLKYAIAERGYRLGSYLNV"
     gene            complement(22931..24283)
                     /gene="celF"
                     /locus_tag="ACHY1N_001240"
                     /gene_synonym="chbF"
     CDS             complement(22931..24283)
                     /gene="celF"
                     /locus_tag="ACHY1N_001240"
                     /gene_synonym="chbF"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFS4043578.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEDG
                     KEKLDIIFELCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLVNGKSRF
                     AELLDGVASGQLKASSVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDAACEVINAIYNDKQA
                     EHYVNIPHHGHIDNIPADWAVEMTCKLGRDGATPHPRITHFDDKVMGLIHTIKGFEIA
                     ASNAALSGEFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
                     "
     gene            complement(24388..25230)
                     /gene="chbR"
                     /locus_tag="ACHY1N_001241"
     CDS             complement(24388..25230)
                     /gene="chbR"
                     /locus_tag="ACHY1N_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HFS4043579.1"
                     /translation="MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDY
                     YEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFE
                     QHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
                     YREEQVIDDVPQWLKSTVEKMHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTP
                     MQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLT
                     EFNQ"
     gene            complement(25238..25588)
                     /gene="chbA"
                     /locus_tag="ACHY1N_001242"
     CDS             complement(25238..25588)
                     /gene="chbA"
                     /locus_tag="ACHY1N_001242"
                     /EC_number="2.7.1.196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HFS4043580.1"
                     /translation="MMDLDNIPDTQTEAEELEEVVMGLIINSGQARSLAYAALKQAKQ
                     GDFAAAKAMMDQSRMALNEAHLVQTKLIEGDAGEGKMKVSLVLVHAQDHLMTSMLARE
                     LITELIELHEKLKA"
     gene            complement(25639..26997)
                     /gene="chbC"
                     /locus_tag="ACHY1N_001243"
     CDS             complement(25639..26997)
                     /gene="chbC"
                     /locus_tag="ACHY1N_001243"
                     /EC_number="2.7.1.196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
                     /protein_id="HFS4043581.1"
                     /translation="MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAM
                     FVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFI
                     GMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
                     EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQII
                     MDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQ
                     YGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLAL
                     PSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTM
                     PTGLGAFFNTNGSVAALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANAL
                     KF"
     gene            complement(27082..27402)
                     /gene="chbB"
                     /locus_tag="ACHY1N_001244"
     CDS             complement(27082..27402)
                     /gene="chbB"
                     /locus_tag="ACHY1N_001244"
                     /EC_number="2.7.1.196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HFS4043582.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKK
                     AAAN"
     gene            complement(27701..28039)
                     /gene="osmE"
                     /locus_tag="ACHY1N_001245"
     CDS             complement(27701..28039)
                     /gene="osmE"
                     /locus_tag="ACHY1N_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HFS4043583.1"
                     /translation="MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQAAK"
     gene            28241..29068
                     /gene="nadE"
                     /locus_tag="ACHY1N_001246"
     CDS             28241..29068
                     /gene="nadE"
                     /locus_tag="ACHY1N_001246"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFS4043584.1"
                     /translation="MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLV
                     LGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLTALGCPEHLYKKAPTADLEDDR
                     PSLPDEVALGVTYDNIDDYLEGKNVPEQVARTIENWYLKTEHKRRPPITVFDDFWKK"
     gene            29298..30185
                     /gene="cho"
                     /locus_tag="ACHY1N_001247"
     CDS             29298..30185
                     /gene="cho"
                     /locus_tag="ACHY1N_001247"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HFS4043585.1"
                     /translation="MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGES
                     DTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIA
                     DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCW
                     PWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPL
                     LSGNYEITELDPANDQRAS"
     gene            complement(30145..30720)
                     /gene="ves"
                     /locus_tag="ACHY1N_001248"
     CDS             complement(30145..30720)
                     /gene="ves"
                     /locus_tag="ACHY1N_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310475.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="environmental stress-induced protein Ves"
                     /protein_id="HFS4043586.1"
                     /translation="MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFHWRASIASIA
                     ANGEFSLFPGMERIVTLLEGGEMFLESADRFNHTLKPLQPFAFAADQVVKAKLTAGQM
                     SMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFD
                     GRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ"
     gene            complement(30923..31408)
                     /gene="spy"
                     /locus_tag="ACHY1N_001249"
     CDS             complement(30923..31408)
                     /gene="spy"
                     /locus_tag="ACHY1N_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone Spy"
                     /protein_id="HFS4043587.1"
                     /translation="MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKF
                     GPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAE
                     AQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATA
                     E"
     gene            complement(31738..32706)
                     /gene="astE"
                     /locus_tag="ACHY1N_001250"
     CDS             complement(31738..32706)
                     /gene="astE"
                     /locus_tag="ACHY1N_001250"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0009017 - succinylglutamate desuccinylase
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HFS4043588.1"
                     /translation="MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQG
                     ALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDM
                     NRMFGGRWQLFAESGETCRARELEQCLEDFYDLGKESVRWHLDLHTAIRGSLHPQFGV
                     LPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFG
                     QNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFM
                     PFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS"
     gene            complement(32699..34042)
                     /gene="astB"
                     /locus_tag="ACHY1N_001251"
     CDS             complement(32699..34042)
                     /gene="astB"
                     /locus_tag="ACHY1N_001251"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009015 - N-succinylarginine dihydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HFS4043589.1"
                     /translation="MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRQAAKQ
                     GLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSS
                     ASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAHVTESLLKAIFNDEEKFS
                     VHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREAS
                     EAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLAN
                     LRARVNGFMAIEVPATQVSVSDAVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGY
                     LNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFN
                     ALNDWVDRYYRDRLTAADLADPQLLRGGREALDVLSQLLNLGSVYPFQREGGGNG"
     gene            complement(34039..35517)
                     /gene="astD"
                     /locus_tag="ACHY1N_001252"
     CDS             complement(34039..35517)
                     /gene="astD"
                     /locus_tag="ACHY1N_001252"
                     /EC_number="1.2.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043824 - succinylglutamate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
                     /protein_id="HFS4043590.1"
                     /translation="MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACR
                     AARAAFPRWARLSLAERQVVVERFAGLLERNKGELTAIIARETGKPRWEAATEVTAMI
                     NKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
                     AGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLF
                     TGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQR
                     CTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAW
                     QQLEAMGGRTLLAPRLLQSETSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEA
                     ILMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGN
                     HRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR"
     gene            complement(35514..36548)
                     /gene="astA"
                     /locus_tag="ACHY1N_001253"
     CDS             complement(35514..36548)
                     /gene="astA"
                     /locus_tag="ACHY1N_001253"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008791 - arginine N-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HFS4043591.1"
                     /translation="MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAI
                     KTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAVGLNDLWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     QEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPAQGDFPACLVANENYHHFRVVLARTDPATERLILTAAQLDALKCHAGDRVRL
                     VRLCAEEKTA"
     gene            complement(36545..37765)
                     /gene="astC"
                     /locus_tag="ACHY1N_001254"
     CDS             complement(36545..37765)
                     /gene="astC"
                     /locus_tag="ACHY1N_001254"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylornithine/acetylornithine transaminase"
                     /protein_id="HFS4043592.1"
                     /translation="MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDF
                     AGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFC
                     NSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
                     LPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNA
                     LLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECARVMTVG
                     THGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTINHRYGLFSEVRG
                     LGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDR
                     FAAACEHFVSRGSS"
     gene            38211..39017
                     /gene="xthA"
                     /locus_tag="ACHY1N_001255"
     CDS             38211..39017
                     /gene="xthA"
                     /locus_tag="ACHY1N_001255"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008311 - double-stranded DNA 3'-5' DNA
                     exonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFS4043593.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKETPIAVRRGFPGDDEEAQRRIIMAEIPSLLGN
                     VTVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRDNPVLIMGDMNISPTDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMDRLMSWGLVDTFRHANPQTADRFSWFDYRSK
                     GFDDNRGLRIDLLLASQPLAECCVETGIDYEIRSMEKPSDHAPVWATFRR"
     gene            39184..39894
                     /gene="ydjX"
                     /locus_tag="ACHY1N_001256"
     CDS             39184..39894
                     /gene="ydjX"
                     /locus_tag="ACHY1N_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416264.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HFS4043594.1"
                     /translation="MNAERNFLFACLIFALVIYAIHAFGLFDLLTDLPHLQTLIRQSG
                     LFGYSLYILLFIIATLFLLPGSILVIAGGIVFGPLLGTLLSLIAATLASSSSFLLARW
                     LGRDLLLKYVGHSHTFQAIEKGIARNGIDFLILTRLIPLFPYNIQNYAYGLTTIAFWP
                     YTLISALTTLPGIVIYTVMASDLASEGITLRFILQLCLAGLALFILVQLAKLYARHKH
                     VDLSASRRSPLTHPKNEG"
     gene            39899..40576
                     /gene="ydjY"
                     /locus_tag="ACHY1N_001257"
     CDS             39899..40576
                     /gene="ydjY"
                     /locus_tag="ACHY1N_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416265.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YdjY"
                     /protein_id="HFS4043595.1"
                     /translation="MSQHYSVSWKKGLAALCLLAVAGLSGCDQKENAAAKVEYDGLSN
                     SQPLRVDANNHTVTMLVQINGRFLTDVTRHGIVFKDGSNGHKSLFMAYATPKAFYEAL
                     KEAGGTPGENMTMDNKETTLVTGSKLDISVNWQGAAKAYSFDEVIVDSNGKKLDMRFG
                     GNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPADNTLAT
                     VTFKITE"
     gene            40591..41298
                     /gene="ydjZ"
                     /locus_tag="ACHY1N_001258"
     CDS             40591..41298
                     /gene="ydjZ"
                     /locus_tag="ACHY1N_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001697152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HFS4043596.1"
                     /translation="MMKIQSRKIWYYRITLIILLFAMLLAWALLPGVHEFINRSVAAF
                     AAVDQQGIERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFANASLFGAFWGGLLS
                     WTSSMAGAALCFFIARVMGREVVEKLTGKTVLDSMDGFFTRYGKHTILVCRLLPFVPF
                     DPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSMLTGGTFWFVTGLFILFALTV
                     VIFMAKKIWLERQKRND"
     gene            41298..41846
                     /gene="ynjA"
                     /locus_tag="ACHY1N_001259"
     CDS             41298..41846
                     /gene="ynjA"
                     /locus_tag="ACHY1N_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFS4043597.1"
                     /translation="MGLPPLSKIPFILRPQAWLHRRHYGEVLSPIRWWGRIPFIFYLV
                     SMFVGWLERKRSPLDPVVRSLVSARIAQMCLCEFCVDITSMKVAERTGSNDKLLAVAD
                     WRQSPLFSDEERLALEYAEAASVTPPTVDDALRTRLAAHFDAQALTELTALIGLQNLS
                     ARFNSAMDIPAQGLCRIPEKRS"
     gene            41856..43022
                     /gene="ynjB"
                     /locus_tag="ACHY1N_001260"
     CDS             41856..43022
                     /gene="ynjB"
                     /locus_tag="ACHY1N_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4043598.1"
                     /translation="MRHCGWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDT
                     AINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTEAAAGRKTGGSVDLLWVNGE
                     NFRTLKEANLLQTGWAETLPNWRYVDTQLPVREDFSVPTQGAESPWGGAQLTFIARRD
                     VTPQPPQTPQALLEFAKVNPGTVTYPRPPDFTGTAFLEQLLIMLTPDPAALKEAPDDA
                     TFARVTAPLWQYLDALHPYLWREGKDFPPSPARMDALLKAGTLRLSLTFSPAHAQQKI
                     ASGDLPASSYSFGFREGMIGNVHFVTIPANANASAAAKVVANFLLSPDAQLRKADPVV
                     WGDPSVLDPQKLPDGQREILQSRMPQDLPPVLAEPHAGWVNALEQEWLRRYGTH"
     gene            42995..44530
                     /gene="ynjC"
                     /locus_tag="ACHY1N_001261"
     CDS             42995..44530
                     /gene="ynjC"
                     /locus_tag="ACHY1N_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416269.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFS4043599.1"
                     /translation="MVTPLRYALIFLLWAMVAVIYAPLIPAALTLISPALSLTHWQAL
                     FADPQLPHALLATLVSTTIAAVGALLIALLVIVALWPGPKWQRMCARLPWLLAIPHVA
                     FATSALLLFADGGLLYDYFPYFTPPMDRFGIGLGLTLAVKESAFLLWILAAVLSEKRL
                     LQQVIVLDSLGYSRWQCLNWLLLPSVAPSLAMAMLAIVAWSLSVVDVAIILGPGNPPT
                     LAVISWQWLTQGDADQQTKGALASLLLMLLLAAYVLLSYLLWRSWRRTIPRVDGIRKP
                     ATPLLPGTTLASFLPLTGVLCVVLLAILADQSTINSEALINSLTMGLVATFIALLLLL
                     LWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLNLDGSWTAVVWGHLLWVMPWML
                     FILQPAWQRIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPVLIAFAVGFSVSIAQYMP
                     TLWLGAGRFPTLTTEAVALSSGGSNGILAAQALWQLLLPLIIFALTALVAKWVGYVRQ
                     GLR"
     gene            44530..45183
                     /gene="ynjD"
                     /locus_tag="ACHY1N_001262"
     CDS             44530..45183
                     /gene="ynjD"
                     /locus_tag="ACHY1N_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFS4043600.1"
                     /translation="MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLF
                     SWMIGALAGQFSCTGELWFNEQRIDMLPTAQRQIGILFQDALLFDQFSVGQNLLLALP
                     STLKGTARRNAVKDALDRAGLAETYHQDPATLSGGQRARVALLRALLAQPKALLLDEP
                     FSRLDVALRDNFRQWVFSEVRELAIPVVQVTHDLQDVPADSSVLDMAQWSENYNKLR"
     gene            45250..46557
                     /gene="ynjE"
                     /locus_tag="ACHY1N_001263"
     CDS             45250..46557
                     /gene="ynjE"
                     /locus_tag="ACHY1N_001263"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416271.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YnjE"
                     /protein_id="HFS4043601.1"
                     /translation="MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAID
                     TRPSAFYNGWPQTLNGPSGHEPAALNLSASWLDKMSTEQLYEWIKQHNLKTDAPVALY
                     GNDKDVDAVKTRLQKAGFTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEV
                     TAKPAGDWKVIEAAWGAPKLYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKH
                     GIRHDTTVILYGRDVYAGARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKV
                     KAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWTEFIGTTSGYSYIKPKGE
                     IAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIKPEQQVSFYCGTGWRAS
                     ETFMYARAMGWKNVSVYDGGWYEWSSDPKNPVATGERGPDSSK"
     gene            complement(46566..47186)
                     /gene="ynjF"
                     /locus_tag="ACHY1N_001264"
     CDS             complement(46566..47186)
                     /gene="ynjF"
                     /locus_tag="ACHY1N_001264"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416272.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFS4043602.1"
                     /translation="MLDRHLHPRIKPLLHQCVRVLDKPGITPDGLTLVGFAIGVLALP
                     FLALGWYLAALVVILLNRLLDGLDGALARRRELTDAGGFLDISLDFLFYALVPFGFIL
                     AAPEQNALAGGWLLFAFIGTGSSFLAFAALAAKHQIDNPGYAHKSFYYLGGLTEGTET
                     ILLFVLGCLFPAWFAWFAWIFGALCWMTTFTRVWSGYLTLKSLQRQ"
     gene            47273..47680
                     /gene="nudG"
                     /locus_tag="ACHY1N_001265"
     CDS             47273..47680
                     /gene="nudG"
                     /locus_tag="ACHY1N_001265"
                     /EC_number="3.6.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP pyrophosphohydrolase"
                     /protein_id="HFS4043603.1"
                     /translation="MKMIEVVAAIIERDGKILLAQRPAQSDQAGLWEFAGGKVELDES
                     QQQALVRELNEELGIEATVGEYVASHQREVSGRIIHLHAWHVPDFHGTLQAHEHQALV
                     WCSPEEALQYPLAPADIPLLEAFMALRAARAAD"
     gene            complement(47646..47918)
                     /gene="ynjH"
                     /locus_tag="ACHY1N_001266"
     CDS             complement(47646..47918)
                     /gene="ynjH"
                     /locus_tag="ACHY1N_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HFS4043604.1"
                     /translation="MSRALFAVVLAFPLIALANPHYRPDVEVNVPPEVFSSGGQSAQP
                     CTQCCVYQDQNYSEGAVIKAEGILLQCQRDDKTLSTNPLLWRRVKP"
     gene            48154..49497
                     /gene="gdhA"
                     /locus_tag="ACHY1N_001267"
     CDS             48154..49497
                     /gene="gdhA"
                     /locus_tag="ACHY1N_001267"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFS4043605.1"
                     /translation="MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPK
                     YRQMSLLERLVEPERVIQFRVVWVDDRNQVQVNRAWRVQFSSAIGPYKGGMRFHPSVN
                     LSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGA
                     DTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYF
                     TEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTK
                     EKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSVPVDIALPCATQNELDVDAAHQ
                     LIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLG
                     WKAEKVDARLHHIMLDIHHACVEHGGEGEQTNYVQGANIAGFVKVADAMLAQGVI"
     gene            complement(49614..50655)
                     /gene="ynjI"
                     /locus_tag="ACHY1N_001268"
                     /pseudo
     CDS             complement(49614..50655)
                     /gene="ynjI"
                     /locus_tag="ACHY1N_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416276.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
     gene            complement(50783..52744)
                     /gene="topB"
                     /locus_tag="ACHY1N_001269"
     CDS             complement(50783..52744)
                     /gene="topB"
                     /locus_tag="ACHY1N_001269"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFS4043606.1"
                     /translation="MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAG
                     DPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIV
                     TSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCR
                     YLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSA
                     INLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRALL
                     GSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMAT
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGG
                     SADKKKAAPRKRSAKNSPPADEAGSGAIA"
     gene            complement(52749..53792)
                     /gene="selD"
                     /locus_tag="ACHY1N_001270"
     CDS             complement(52749..53792)
                     /gene="selD"
                     /locus_tag="ACHY1N_001270"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004756 - selenide, water dikinase
                     activity [Evidence IEA];
                     GO_process: GO:0016260 - selenocysteine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HFS4043607.1"
                     /translation="MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFAN
                     IEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTER
                     NFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKTTAAEFGIELTAIGEL
                     VPARGGRAMVEIR"
     gene            complement(53909..54460)
                     /gene="ydjA"
                     /locus_tag="ACHY1N_001271"
     CDS             complement(53909..54460)
                     /gene="ydjA"
                     /locus_tag="ACHY1N_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HFS4043608.1"
                     /translation="MDALELLINRRSASRLAEPAPTGEQLQNILRAGMRAPDHKSMQP
                     WHFFVIEGEGRERFSAVLEQGAIAAGSDDKAIDKARNAPFRAPLIITVVAKCEENHKV
                     PRWEQEMSAGCAVMAMQMAAVAQGFGGIWRSGALTESPVVREAFGCREQDKIVGFLYL
                     GTPQLKASTSINVPDPTPFVTYF"
     gene            54621..56477
                     /gene="sppA"
                     /locus_tag="ACHY1N_001272"
     CDS             54621..56477
                     /gene="sppA"
                     /locus_tag="ACHY1N_001272"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707347.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFS4043609.1"
                     /translation="MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQ
                     VSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVN
                     TIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQY
                     YLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLNTVAANRQIPAQQVFPGAQGLLEGLTKTGGDTAKYA
                     LENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFAN
                     GAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGV
                     HTDGVSTSPLADVSITRALPPEAQQMMQLSIENGYKRFITLVADARHSTPEQIDKIAQ
                     GHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSG
                     SVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANVR"
     gene            56644..57660
                     /gene="ansA"
                     /locus_tag="ACHY1N_001273"
     CDS             56644..57660
                     /gene="ansA"
                     /locus_tag="ACHY1N_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004067 - asparaginase activity [Evidence
                     IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFS4043610.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRP
                     EMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALS
                     FMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIY
                     PGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELQEASDRGIVVVNLTQCMSG
                     KVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQELDTETICKAMSQNLRGEL
                     TPDD"
     gene            57671..58312
                     /gene="pncA"
                     /locus_tag="ACHY1N_001274"
     CDS             57671..58312
                     /gene="pncA"
                     /locus_tag="ACHY1N_001274"
                     /EC_number="3.5.1.-"
                     /EC_number="3.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310502.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nicotinamidase/pyrazinamidase"
                     /protein_id="HFS4043611.1"
                     /translation="MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRG
                     EAVIASQDWHPANHGSFASQHCVEPYMPGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQ
                     KAIAAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFT
                     VLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQG"
     gene            complement(58473..58745)
                     /gene="yeaC"
                     /locus_tag="ACHY1N_001275"
     CDS             complement(58473..58745)
                     /gene="yeaC"
                     /locus_tag="ACHY1N_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707337.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HFS4043612.1"
                     /translation="MNLDDIINSMTPEVYQRLSTAVELGKWPDGVALTEEQKENCLQL
                     VMLWQARHNTEAQHMTIDTNGQMVMKSKQQLKEDFGISAKPIAMFK"
     gene            complement(58787..59200)
                     /gene="msrB"
                     /locus_tag="ACHY1N_001276"
     CDS             complement(58787..59200)
                     /gene="msrB"
                     /locus_tag="ACHY1N_001276"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFS4043613.1"
                     /translation="MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVY
                     HCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLRFTDGENGEEING"
     gene            59542..60537
                     /gene="gapA"
                     /locus_tag="ACHY1N_001277"
     CDS             59542..60537
                     /gene="gapA"
                     /locus_tag="ACHY1N_001277"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006322611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFS4043614.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLT
                     DETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            60621..61505
                     /gene="yeaD"
                     /locus_tag="ACHY1N_001278"
     CDS             60621..61505
                     /gene="yeaD"
                     /locus_tag="ACHY1N_001278"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
                     /protein_id="HFS4043615.1"
                     /translation="MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQG
                     AHLLSWKPAGEEEVLWLSNNTPFKNGVAIRGGVPVCWPWFGPAAQQGLPAHGFARNLP
                     WTLKSHREDADGVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLESHGEFETT
                     SALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKEDVLTDGIQTFPDRTDRVYLNPQDCS
                     VINDEALNRIIAVGHQHHLNVVGWNPGPALSVSMGDMPDDGYKTFVCVETAYASETQK
                     VTKEKPAHLAQSIRVAKR"
     gene            complement(61556..62410)
                     /gene="yeaE"
                     /locus_tag="ACHY1N_001279"
     CDS             complement(61556..62410)
                     /gene="yeaE"
                     /locus_tag="ACHY1N_001279"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal reductase YeaE"
                     /protein_id="HFS4043616.1"
                     /translation="MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIEL
                     GLTLIDTAEMYADGGAEKVVGEALTDLRDNVFLVSKVYPWNAGGQKAINACEASLRRL
                     NTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
                     CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHA
                     HNISAAQVLLAWVISHQGVMAIPKAATIAHVQQNAAVLEVELSSAELIMLDKAYPAPK
                     GKTALDMV"
     gene            complement(62500..63246)
                     /gene="mipA"
                     /locus_tag="ACHY1N_001280"
     CDS             complement(62500..63246)
                     /gene="mipA"
                     /locus_tag="ACHY1N_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="scaffolding protein MipA"
                     /protein_id="HFS4043617.1"
                     /translation="MTKLKLLALGVLIATSAGVAHAEGKFSLGAGVGVVEHPYKDYDT
                     DVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGDHQMRHL
                     DDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
                     GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTAR
                     YTRLSDEVTDSPMVDKSWTGLISTGITYKF"
     gene            63682..65616
                     /gene="yeaG"
                     /locus_tag="ACHY1N_001281"
     CDS             63682..65616
                     /gene="yeaG"
                     /locus_tag="ACHY1N_001281"
                     /EC_number="2.7.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011411173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HFS4043618.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLM
                     AIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWSSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            65729..67012
                     /gene="yeaH"
                     /locus_tag="ACHY1N_001282"
     CDS             65729..67012
                     /gene="yeaH"
                     /locus_tag="ACHY1N_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HFS4043619.1"
                     /translation="MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVT
                     DVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQ
                     GQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGV
                     PANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAE
                     LRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILL
                     YLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNP
                     AQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHL
                     QSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD"
     gene            67159..68634
                     /gene="cdgI"
                     /locus_tag="ACHY1N_001283"
     CDS             67159..68634
                     /gene="cdgI"
                     /locus_tag="ACHY1N_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFS4043620.1"
                     /translation="MIQSTRISMGLFFKYFLSLTKIDPGQNYISLPSIKSSTHIALLF
                     MVSMGTQKLKAQSFFIFSLLLTLILFCITTLYNENTNVKLIPQMNYLMVVVALFFLNA
                     IIFLFMLMKYFTNKQILPTLILSLAFLSGLIYLVETIVVIHKPISDSTLIQTKSNDVS
                     IFYIFRQLSFICLTSLALFCYGKDNILDNNKKKTGILLLALIPFLVFPLLAHNLSSYN
                     ADYSLYVVDYCPDNHTATWGINYTKILVCLWAFLLFFIIMRTRLASELWPLIALLCLA
                     SLCCNLLLLTLDEYNYTIWYISRGIEVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLT
                     NIYNRRYFFNSVESLLSRPVVKDFCVMLVDINQFKRINAQWGHRVGDKVLVSIVDIIQ
                     QSIRPDDILARLEGEVFGLLFTELNSAQAKIIAERMRKNVELLTGFSNRYDVPEQMTI
                     SIGTVFSTGDTRNISLVMTEADKALREAKSEGGNKVIIHHI"
     gene            68815..70305
                     /gene="dgcJ"
                     /locus_tag="ACHY1N_001284"
     CDS             68815..70305
                     /gene="dgcJ"
                     /locus_tag="ACHY1N_001284"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0043709 - cell adhesion involved in
                     single-species biofilm formation [Evidence IEA];
                     GO_process: GO:1902201 - negative regulation of
                     bacterial-type flagellum-dependent cell motility [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcJ"
                     /protein_id="HFS4043621.1"
                     /translation="MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQ
                     KADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEKRRAICEAFESANNTHGLNLTAHK
                     YPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDL
                     NDRYVYFYEPVNVEYFAMNNWSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQN
                     VMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIII
                     NQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHF
                     RLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDT
                     LGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRL
                     QHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS"
     gene            70348..70851
                     /gene="yeaK"
                     /locus_tag="ACHY1N_001285"
     CDS             70348..70851
                     /gene="yeaK"
                     /locus_tag="ACHY1N_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mischarged aminoacyl-tRNA deacylase"
                     /protein_id="HFS4043622.1"
                     /translation="MTEMAKGSVTHQRLIALLSQEGANFRVVTHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHIGGLRASLASPAEVDEL
                     TGCVFGAIPPFSFHPKLKLVADPLLFERFDEIAFNAGMLDKSVILKTADYLRIAQPEL
                     VNFRRTA"
     gene            complement(70852..70956)
                     /gene="yoaI"
                     /locus_tag="ACHY1N_001286"
     CDS             complement(70852..70956)
                     /gene="yoaI"
                     /locus_tag="ACHY1N_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416302.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small membrane protein YoaI"
                     /protein_id="HFS4043623.1"
                     /translation="MNDQMFVETLIISSSFFAIAVVLVLSVLLIERTG"
     gene            71126..71572
                     /gene="yeaL"
                     /locus_tag="ACHY1N_001287"
     CDS             71126..71572
                     /gene="yeaL"
                     /locus_tag="ACHY1N_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFS4043624.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFP
                     WIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRG
                     VTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            complement(71529..72350)
                     /gene="nimR"
                     /locus_tag="ACHY1N_001288"
     CDS             complement(71529..72350)
                     /gene="nimR"
                     /locus_tag="ACHY1N_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NimR"
                     /protein_id="HFS4043625.1"
                     /translation="MMHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLI
                     LALHGAITCTVENALWMVPPQYAVWIPGGVEHSNQVTANAELCFLFIEPSAVIMPTTC
                     CTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPVSSHPKI
                     RAMVEMMAKEPVEWGSLGQWACFFAMSERNIARLIVKETGLSFRQWRQQLQLIMALQG
                     LVKGDTVQKVAHTLGYDSTTAFITMFKKGLGQTPGRYIAGLTTVSPQSAKPDPRQ"
     gene            72447..73628
                     /gene="nimT"
                     /locus_tag="ACHY1N_001289"
     CDS             72447..73628
                     /gene="nimT"
                     /locus_tag="ACHY1N_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-nitroimidazole transporter"
                     /protein_id="HFS4043626.1"
                     /translation="MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAY
                     SLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPY
                     LLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
                     LNGFGWQGALFMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTL
                     FLGINSLVYYVIIGWLPAILISRGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQ
                     RGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPLMGKIHDANGDWSVPLMGVAILSLLMAIFGLCAGRDKEI
                     R"
     gene            73683..74030
                     /gene="yeaO"
                     /locus_tag="ACHY1N_001290"
     CDS             73683..74030
                     /gene="yeaO"
                     /locus_tag="ACHY1N_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFS4043627.1"
                     /translation="MNIQCKRVYDPAEQSDGYRVLVDRLWPRGIKKTDLALDEWDKEI
                     TPSTELRKAFHGEVVDFATFREQYLAELAQHEQEGKRLADIAKKQPLTLLYAAKNTTQ
                     NHALVLADWLRSL"
     gene            complement(74052..74306)
                     /gene="yoaF"
                     /locus_tag="ACHY1N_001291"
     CDS             complement(74052..74306)
                     /gene="yoaF"
                     /locus_tag="ACHY1N_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing lipoprotein YoaF"
                     /protein_id="HFS4043628.1"
                     /translation="MKIISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPASVYCQQK
                     GGTLIPVQTAQGVSNNCKLPGGETIDEWALWRRYHPAGEK"
     gene            74489..75514
                     /gene="dgcP"
                     /locus_tag="ACHY1N_001292"
     CDS             74489..75514
                     /gene="dgcP"
                     /locus_tag="ACHY1N_001292"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416308.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcP"
                     /protein_id="HFS4043629.1"
                     /translation="MSDQIIARVSQSLAKEQSLESLVRQLLEMLEMVTDMESTYLTKV
                     DVEARLQHIMFARNSQKMHIPENFTVSWDYSLCKRAIDENCFFSDEVPDRWGDCIAAR
                     NLGITTFLSTPIHLPDGSFYGTLCAASSEKRQWSERAEQVLQLFAGLIAQYIQKEALV
                     EQLREANAALIAQSYTDSLTGLPNRRAIFENLTTLFSLARHLNHKIMIAFIDLDNFKL
                     INDRFGHNSGDLFLIQVGERLNTLQQNGEVIGRLGGDEFLVVSLNNENADISSLRERI
                     QQQIRGEYHLDDVDLYYPGASLGIVEVDPETTDADSALHAADIAMYQEKKHKQKTPFV
                     AHPALHS"
     gene            75547..75645
                     /gene="yoaK"
                     /locus_tag="ACHY1N_001293"
     CDS             75547..75645
                     /gene="yoaK"
                     /locus_tag="ACHY1N_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HFS4043630.1"
                     /translation="MRIGIIFPVVIFITAVVFLAWFFIGGYAAPGA"
     gene            75648..75722
                     /gene="yoaJ"
                     /locus_tag="ACHY1N_001294"
     CDS             75648..75722
                     /gene="yoaJ"
                     /locus_tag="ACHY1N_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YoaJ"
                     /protein_id="HFS4043631.1"
                     /translation="MKKTTIIMMGVAIIVVLGTELGWW"
     gene            complement(75781..76029)
                     /gene="yeaQ"
                     /locus_tag="ACHY1N_001295"
     CDS             complement(75781..76029)
                     /gene="yeaQ"
                     /locus_tag="ACHY1N_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4043632.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTILLGIVGAVVGG
                     WISTLFGFGKVDGFNFGSFVVAVIGAIVVLFIYRKIKS"
     gene            complement(76257..>76833)
                     /locus_tag="ACHY1N_001296"
     CDS             complement(76257..>76833)
                     /locus_tag="ACHY1N_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415949.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HFS4043633.1"
                     /translation="ARLQRQLSRKVKFSNNWQKQKRKIQRLHSRIANIRRDYLHKVTT
                     TVSKNHAMIVIEDLKVSNMSKSAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLEY
                     KQLWRGGQVLAVPPAYTSQRCACCGHTAKENRLSQSQFRCQVCGYTANADVNGARNIL
                     AAGHAVLACGEMVQSGRSLKQEPTEMIQATA"
BASE COUNT        19238 a        19617 c        18439 g        19539 t
ORIGIN      
        1 gcattttcaa ccataacaga aatggtgcag acatacattc aagagcagaa gaaaagacag
       61 aaaagttcta ttagcgcaca aatcaaaaca tgagggtgta ctcaaataat acaatgctat
      121 agtaaatcta taagtgcata actatttcct gatcttttcc caaaatagat gacaggataa
      181 aaaacattcc aatcttttac aggctttgga taaatcgtat caaagcctat ttcttcaaga
      241 gttaaatcac cgcttttcgc tcgaaacgga ctggctgttg gagtatgagc cagaacaact
      301 tagaatagcc cctgcactac gttaagggag gccgctatgt tccgttgtcc gctttgtcgc
      361 gcatctgccc gtatccgcac cagtcgtcct gaaaatgatt caaacaccgt gcggcaaaag
      421 tattaccagt gtaacaatct agaatgcggc gtatgcttct caacactgga agcttttcat
      481 aaattcacat cgaaacacgc ctccggcgtt cactcttcag aaggtatccc gtggcatgag
      541 ctgccagctt cacacagggg aaacaatcag atgagtttgc ctttgcctca aaattaacag
      601 gcagaattgc cggagtaaca aaaaagcgat agattacgcg cgggtgcctt tcggctgatg
      661 gtcggaggga atacccgaag gccagatgtg gaaaggcccc ggaaaacatc tctgtttaac
      721 cgaggcccta accgcattac cttgacaagt gaaaggttag cgcctctccg gaaaaggagc
      781 aagtgctatg tcgcaaaaat cgcttacggc catcacgttc tgtgtgacgg caatcctcat
      841 catctggatg ttgcacggtt cgctgtgtga aatacggatg agcttctggg gagcggagtt
      901 tgcggcgttc ttacagtgta agcagtaagg aaaccgcgac gggggagcta tcccccgtca
      961 atcggttgcc agggtaaggc cggataaggc accctatctc acagatatga acaacaaacc
     1021 cgcagcgtaa aaactgcggg ttttcttttt ggtgccctca ccgacttgaa acagtgataa
     1081 aactataaga caaagcccgc aatgtagcgg gcttactccc ctcaccctcc actgaatgtg
     1141 gacacacagt ggaacgaagc ggcataagat attataaatc aatcagttat tgaaagaaaa
     1201 aaggccgcag agcggccttt ttagttagat cagattactc gtctttgggc gaagcgtttt
     1261 cgacccggct ttttaacttc tgcccgggtc tgaaggtcac cacgcgccgt gctgtaatgg
     1321 gaatatcctc gcccgttttc gggttacgtc ccgggcgttg attcttatca cgcagatcga
     1381 agttaccaaa accagagagt ttcacctgtt cgccgttttc cagagcgcga cggatctctt
     1441 cgaaaaacag ttcaaccagt tctttggcat cccgcttgct aagcccaagc ttatcaaaca
     1501 gatattctga catttcagct tttgtaagcg ccataggttc aatccctcaa tgatgcctgg
     1561 aatcgctctt ttaatgcctc tacacatttg gcgacggtag cggcaatctc ctcttcttcg
     1621 agtgtacggc tggtatcttg caggatcagg cttatggcga ggctcttata cccctccgca
     1681 acacccttac cgcggtacac gtcaaataag tttacgccaa ctacctgatt tacgccaact
     1741 ttcttacatt cggataaaat atccgctgcg ggaacgtttt ctgcgaccac caccgcgatg
     1801 tcacgacggt tcgccgggaa gcgagaaatc tcgcgcgcct gaggcaccac gcggtctgcg
     1861 agcttgttcc actccagttc gaacaccaga gtgcgaccgt taagatccag tttacgttcc
     1921 agttcaggat gaacaacccc aacaaaacca atacgtttac ctttcagata aatcgctgcg
     1981 gattgccccg gatgcagtgc cggattcgct tctgcacgga actcaacctc attcagttta
     2041 ccggtcaggt cgagaacgga ttcaagatcg cctttcaaat catagaaatc aacggtctct
     2101 tttgccaggt tccagtgctc ttcgtaacgg ttaccgcaaa tcacaccggc taacatcaga
     2161 tcctgacgaa tgcccaacgg tgcctgagta tctggtacga aacgcagacc gctttcgaaa
     2221 atgcgcacac ggttctgctg acggttctgg ttgtacacca cggttgccag caggccggtc
     2281 cacagagaaa gacgcattgc tgacatttca acagagatcg ggcttggcag cagtaaggct
     2341 tcaacgcctg gatggatcat ctgctgcact ttcggatcaa cgaagctgta ggtgatcact
     2401 tcctgatagc ctttgtcgtt gagcagcgtt ttcacgcgct tgagcgacag gtcagcttca
     2461 cggtgagtac ccataatcag gcttgcctgt accggctcat ccgggatgtt gttgtagccg
     2521 taaacacgcg cgacttcttc gaccagatct tcttcaatct ccatatcgaa acgccagctc
     2581 ggcgcaactg cctgccactc gtctttgcct tcggtcactt cgcagccgag acgacgcaga
     2641 atgtcagtta cctgctcatc cgcaatatga tggccgatca ggcgatccag tttgctacga
     2701 cgtaaagtga tggttgcacg cttcggcagc gttgcttcgt tggtgatatc aattaccgga
     2761 ccagcctcac caccgcagat gtcgatcagc agacgggtcg cacgttccat cgctttgtgc
     2821 tgcagtgccg gatcaacgcc acgctcataa cggtgagacg catcagtatg caggctatga
     2881 cgacgagcac gaccggtgat agacagcggg ctgaagaaag cgcattccag caagacgttt
     2941 tgcgtttcgt cattcacgcc agagtgttcg ccaccaaaga tgccgcccat cgccagcgcc
     3001 ttgttgtggt cggcgatgac cagagtgtca gcattcagct tcgcttcagt gccatcaagc
     3061 agtaccaacg tttcgccctc tttcgccatc cgcaccacaa tgccgccttc aatgcgatct
     3121 ttatcgaaag cgtgcatcgg ctggcccagt tcgagcagta catagttggt gacgtcaaca
     3181 actgcatcga tagaacggat cccgcaacga cgcagttttt ctttcatcca cagcggagtt
     3241 ggcgctttaa cgttaatgcc ttttaccaca cggccaagat aacgcgggca ggcttccggc
     3301 gcttcgactg taatcggcag cgtgtcgtcg atggtcgcac caaccggaac gatttccggt
     3361 tcaaccagcg gcagctgatt cagcacggca acgtcacgcg caacaccaat gatacctaaa
     3421 cagtcggcac ggtttggcgt cacgctgatt tcgatggtgt tgtcatcaag tttcaggtat
     3481 tcacggatgt cggtgccaat cggcgcatcc gcaggcagct cgataatgcc gctatgatcg
     3541 tcagaaattc ccagctcaga aaaggagcac agcatccctt cagacggttc accacgcagt
     3601 ttcgccgctt taattttgaa atcacccggc agaacagcac caatggtagc taccgccaca
     3661 cgcaggccct gacggcagtt tggcgcaccg cagacgatgt ccagcaggcg atcgccgcca
     3721 acattcactt ttgtcacacg cagtttgtca gcgttcggat gctgcgcaca ctcaaccact
     3781 tcaccaacga ccacgccgtg gaagctaccg gcaaccggtt ctacaccgtc aacttccagg
     3841 cccgccatag tgatttgatt cgccagcgca tcgctatcaa tcgccgggtt cacccattcg
     3901 cgtaaccaca gttcactgaa tttcataatc tattcctgcc ttatttaaac tgtttgagga
     3961 aacgcagatc attttcgaag aatgaacgca ggtcggtgac gccgtaacgc aacatagtca
     4021 gacgctccat ccccatcccg aaggcgaaac cagagtaaac ttccgggtcg atgccaacgt
     4081 tacgcagcac gttcggatgc accatcccgc aacccagcac ttccagccat ttaccgtttt
     4141 tacccatgac gtcaacttct gcagaaggct cggtgaacgg gaagtaggaa ggacggaagc
     4201 gaatctgcaa atcttcctca aagaagttac gcaggaaatc gtgcagagtg cctttcaggt
     4261 tggtaaagct gatgttggta tcaacaatca gaccttccat ctgatggaac atcggcgtgt
     4321 gagtctggtc gtagtcgtta cgataaacgc ggccaggcgc aatgatacga atcggtggct
     4381 gctgggcttt catggtgcgg atctgtacgc cagaggtctg ggtacgcagc aggcgggtag
     4441 tgtcaaacca gaaagtgtcg tggtcagcgc gcgccgggtg gtgaccagga atgttcagag
     4501 catcgaagtt atgataatcg tcttcgattt ccggcccggt tgccacggta aagccaagct
     4561 caccgaagaa actttcgata cggtcgatag tacgggtaac cggatgcaga ccgccgtttt
     4621 caatgcgacg acctggcaga gagacatcaa tcgtttccgc cgccagacgc gcattcagtg
     4681 cagcgctttc cagttccgct ttacgcgcat tcagcgcctg ctgaacctgc tctttcgctt
     4741 cgttgataac cgcaccagct gccggacgct cttctggcgg cagctcacgc agggtcgtca
     4801 tctgaagggt taagtgccct tttttaccca aatattcgac gcgcacatta tctaacgcgg
     4861 caacatctga cgcctggcta atggccgcct tcgcactggc aaccagttct gcgagatgtg
     4921 acatggtttt cctcattgtg tcagtggtga cactggttcg ttggacttag agcctatccc
     4981 atcaggctat tttacttgcc attttggtcc cgggcagtgc tcgaaattct cacgtactta
     5041 aatacgctcc ggtttctccg cgctggccgt gtccagactg gctgcgacaa ttacacctga
     5101 tgagacaggc tttttatttt tcaaaacgcg catacaaaaa aagcctccac tgggaggctt
     5161 tcaggcgctg ttttccgttt ctcttctcac gcgctagcct cctggattca ggtgctaaag
     5221 taaaaaaaga agcggaaaat agcagcattc attgcttgcg ttaccttttg gtactcttca
     5281 aaagaccttt attgaaaagg ctacggcgat aaaagtcaat gttttgatgg cgttgaaacg
     5341 aaaagaggga gactagctcc ctctttcaac tggcttatgc cagagctgct ttcgcttttt
     5401 caaccagagc ggtgaacgct actttgtcga atactgcgat atcagccagg atcttacggt
     5461 cgatttcaac agaggctttt ttcaggccat tgatgaattt gctgtaagaa ataccgttct
     5521 gacgtgctgc tgcgttgata cgcgcaatcc acagttgacg gaactgacgc ttacgttgac
     5581 gacggtcacg gtaagcatac tgaccagctt tgataacagc ctggaaggca acgcggtata
     5641 cgcgagaacg cgcaccgtag tagcctttag cttgtttcaa aattttcttg tgacgtgcgc
     5701 gtgcaataac accacgtttt acgcgagcca tatgtgctct cctgtatcta tattctaatt
     5761 aaaaagttaa aaacgttaac ggcttatgcg tacggcaggc acgcgattac caggcccaga
     5821 tcgcctttgg aaaccatggc tttcggacgc aggtgacgtt tacgtttggt cgcttttttg
     5881 gtcagaatgt gacgcaggtt agcgtgcttg tgcttaaaac cacctttacc ggtttttttg
     5941 aagcgcttag cagcaccgcg tacggtctta atttttggca ttttaataac ttccacttcg
     6001 cattgttaat aaacgaaaca aaggcgaaca aagcctgtga agcccgaagg ctccacagac
     6061 agtgctactt gaaggcctta ctgtttcttc ttaggagcga gcaccatgat catctggcgg
     6121 ccttcgatct tcgttgggaa ggattcgacc actgccagtt cttgcaaatc gtctttcacg
     6181 cgattaagca cttccatacc gatttgctgg tgcgccatct cacgaccgcg gaaacgcagc
     6241 gtgattttgg ctttatcacc ctcttcgaga aagcgaatca ggctgcggag ttttacctga
     6301 tagtcgcctt catctgtacc aggacggaat ttaatttcct taacctggat aactttttgc
     6361 tttttcttct gttccttaga agacttgctc ttttcataga ggaatttgcc gtaatccatt
     6421 atacgacaaa ccggcggctc ggcgttaggg ctgatctcga ctaagtctac tccggcttct
     6481 tctgctttct ccagagcttc tctcagactc acaataccaa gctgctcgcc ttccagacct
     6541 gttaagcgaa cttcctgggc gcgaatttcg ccattgatac ggttagggcg cgccgtttga
     6601 actcgttttc cgcctttaat accttattcc tccaattgtt taagactgcg gctgcgaatc
     6661 tcttgttgca gcttctcgat cacttcattt acgtccatgc ttcccaggtc tttaccacgg
     6721 cgggtgcgaa cggcaacttt gcctgattcc acctctttat caccacagac cagcatatat
     6781 gggacgcgac gcaaagtgtg ctcgcggatt ttaaagccaa tcttctcatt tctcaagtct
     6841 gctttaacac gaatgcccgc atttgatagt ttttgcgtca attcgttaac gtattcagac
     6901 tgtgaatcgg taatattcat gataacaacc tgaactggcg caagccaggt cgggaagaaa
     6961 ccagcgaatt cttcggtcag gataccgatg aaacgttcca tcgatcccag aattgcgcgg
     7021 tgaatcatta ccggtacttt acgttcattg tcttcgccta cataagaagc gctcagacga
     7081 gaaggcaaag agaagtccag ctgtactgta ccgcactgcc atgcacgatc gaggcagtca
     7141 tacagggtaa attcaatttt cggaccgtag aaagcgcctt cacccagttg atattcaaac
     7201 gggatgttgt tttcttccag cgcaaccgcc aggtccgcct cagcacgatc ccacatttca
     7261 tcactgccaa tacgtttttc aggacgagtg gagagtttga cgacgatctt ctcgaagcca
     7321 aaagtgctgt acatatcata gactaaacgg atacatccgt taacttcatc gcgaatttgt
     7381 tcttcagtac agaagatatg cgcgtcatcc tgggtaaatc cacgcacgcg catcaggcca
     7441 tgcagcgaac ctgacggctc attacggtgg cagctaccaa actcggccat acgcagcggc
     7501 agatcgcgat aagacttcag cccctggttg aaaatttgta cgtgacccgg gcagttcatc
     7561 ggcttaatgc agtattcacg gttctcagaa gacgtggtga acattgcatc tttgtagttg
     7621 tcccagtgac cggttttttc ccacaggaca cggtccatca tgaacggacc tttaacttcc
     7681 tgatactggt actctttcag tttagaacga acaaacattt ctagttcacg gaagatggtc
     7741 cagccgtcgt tgtgccagaa taccataccc ggcgcttctt cctgcatatg gtacaggtcg
     7801 agctgtttac cgattttacg gtggtcgcgt ttcgcggctt cttccaggcg ctgcaggtaa
     7861 gcgttaagcg cttttttgtc tgcccacgcc gtaccgtaaa tacgttgcaa cattttgttg
     7921 ttgctgtcgc cacgccagta agcccctgcc gttttcatta gtttgaaatg atggcagaaa
     7981 cgcatgttcg gtacgtgcgg accgcggcac atatcgacat attcttcatg gaagtacaga
     8041 cctggcttgt catcatgggc gatgttttcg tcaagaatgg agactttgta gctctcccca
     8101 cggttggcga aagtttcacg cgcttcgtgc cagctgactt tcttcttaat gacgtcgtag
     8161 tttttctcag caagctcatg catccgcttc tcgagtgctt cgacatcttc ctgggttaac
     8221 gtgcggtcaa gatcaacgtc gtaataaaaa ccgttgtcaa taaccgggcc gattgccatt
     8281 ttggtatgcg gccaaagttg tttaatcgcg tgccctaaca ggtgcgcaca ggagtgacga
     8341 atgatctcca gaccgtcttc gtctttggcg gtaatgatgg acagttgtgc gtcgttttca
     8401 atcagatcgc aagcatcaac cagttcgcca ttaacgcgcc ctgcgataca ggctttcgcc
     8461 agacctggac caatgtccag cgcaacatcc atggggctta cagcgtggtc gtaatggcgt
     8521 tggctgccat caggaagagt tataacaggc attttatatc cttatttgca gtggtgaccc
     8581 acacgaaaga tcacatacaa agaaaaattt gtttattaac agttcattgc gaaaccatct
     8641 agccaacaaa tgctaaattg gttcgcaatc aggtacacaa atgaaagaca ttaacctctc
     8701 accttccacc cggttgagcg atgttaacac taaaaaaagg gagattgtac ctttccgttt
     8761 cacattgatt cgattcgcaa ttcgtttgta gtgagtacac cagcaaaacg cttaaagaac
     8821 cactgataac atcacggtgc gtctgaaagg tttactgcga gcggatttac agcagcataa
     8881 actgaatcca gcaaagttcg ttgcgtgatt tggcggtagt attttaaacg ctcatgagat
     8941 taatgacgaa gtggtcatat cacaatgata aaagtgacac aattcttata acaatttttc
     9001 gtgcacattt cgttctggcg ataataatta atcatcatcc tcaaaacctc cagatatata
     9061 taaggcgaat agattatgag tcaaaacgat atcattatca gaactcatta taagtctcct
     9121 catagattgc acatcgatag cgacatacca acaccttcat cagagcctat taataaattt
     9181 gcgcgccagc tcatcaccct acttgatacc tctgacttaa gttcgatgct gtcatactgt
     9241 gttattcagg aatttaccgc aaactgtcga aaaatatcac aaaattgtta ttccactgcc
     9301 ctttttacca ttaactttgc cacttcaccc atccatgcag aaaatatact cattacatta
     9361 cactataaaa aagatttcat ttccttatta ctggaaacca cgcctattaa agctaaccat
     9421 ttgcgaagca tactggatta tattgaacag gaacagttaa ctgctgaaga tcgtaaccat
     9481 tgtatgaaac tgtctaaaaa aatccataga gaaaaaacta tacacccaac agtaaatctc
     9541 aatggtagtg catgtttttt gcaatctcct tctgacgcta ttttttgtcg ccatctgtca
     9601 ttgcaatacg cccttgattc attgagaaat ggaaaaggca aagtcaacct gattaaacat
     9661 tactcctccg ttgaatccat acagcagcat atccccttag tccgggatgc ggagttcaga
     9721 gcattacttc gccatcctcc tgcagggagt cgcgttatcg cgagtaagga ttttggcttc
     9781 gctttagata ttttcttttg tcgaatgatg gcaaacaatg tcagtcatat gtccgcgatt
     9841 ttatatatag acaatcatac tttgtcagta aggctacgaa taaagcagtc agtgtatgga
     9901 caattaaatt atgttgtgtc tgtttacgac ccgaacgata ccaacgttgc cgtcagaggc
     9961 acccacagga cagcacggcg ctttctctcg cttgataagt tcatcagttc agctcccgat
    10021 gctcagacct gggctgatag gtatgttcgc aactgtgcaa ttgctattct tcctctatta
    10081 cctgagggag ttccagttgc tattttagcg ggtatcacga cacgaatgcc atttgcccct
    10141 atacatccat cggcaatgtt gttaataatg gccacaggcc agactcaata gcttattaca
    10201 ctattcaaac agttgcccat actccctgaa aaagaaatca ttgaaataat aactgcgcag
    10261 aatagcgttg gtacacctgc tttatttcta gctatgatga acggacaaac tgacaacgta
    10321 aaaatattta tgcaagaaat ccagtcactg gtatacaatc atatcattca tgaagataat
    10381 ctggttaaat tactgcaaac taaaagtgct aacgaaacac ctagactcta tatctccatg
    10441 ttgtatggat tcgatgaaat aatcgatatc tttctgaatg cattaaccac tccaatagca
    10501 caagaacttt taaacaaaaa aatggtgatg gatattttag ccatgaaaac acgtgatggt
    10561 gaaccagggt tatttgctgc aatggaaaat aatcaccctt tgtgtgccac acggttcctc
    10621 tctaaagttt atgggatcgc cgttaaatat aaactcagca aaatcaacat catggactta
    10681 ttaaaaggcg cgacagcaca tggaacccct gctttataca tcgccatgag caagggtaat
    10741 aaagacgtcg tgttatctta tatatcaaca ctgagtactt ttgcaaaaaa atattctttt
    10801 agtcaacgtc aattattcac actgttggcc gctaaaaatc atgaaaacat gtcagctgtt
    10861 catatagcca ttcatcataa tcattataaa actgtagaaa catattatgc tgctattaat
    10921 gcaatcagcc aaagcctgag ttttagtgct gatgaactaa aaacgtattt ataaccagct
    10981 atttatgata tttgtatatc gatacataat tttatttttt tcataaaacg cagaaacagt
    11041 gatcaggtgt acaacgccac ccgacggctg taataacaaa aaatcccttg atgcctgtcc
    11101 cttttgttac actccgttat cacgcacaag agatatgcag gacactggta tgccgactaa
    11161 acgctttgat aaaaaacact ggaagatggt ggtggtgcta ctggcaatct gtggcgctat
    11221 gttgttgcta cgttgggcag caatgatttg gggctgagca gtgacaaacg aagacagcca
    11281 gaccgcataa cacggtccgg cagataattt tacatgctgt agcccagcga taaggttgtc
    11341 cgacgatcgg tatgttccgg tgcagactct ggaggttcag agttccatgt gacgttgtaa
    11401 gccactttca gtccaaaatg ttcattaata gcaacattta atgcgctttc ggagttcagc
    11461 gttgtgtctt ccgcgccaaa gacggaaaca ccctgcgtaa atttagcgtt gtcagtcaac
    11521 tgccatgcat aagcaccgga ggcatagccc agcggctgag tttcactggc attgtcggta
    11581 tatttgtcgt aacgcacacc tggaccgaat tcaaagcgga aactgtgtac cgggccattc
    11641 aaaaactgac gaccataacc cgcggtcaac acatcgcgct ctcgatagcc gttataacgg
    11701 tctgtcagcc agcttgcctg accaaataaa tagtcataat cagttaaatt aaaacggcta
    11761 cgcccgcccg ccgcatattt ttctgaagaa cgctcatcat tagaagaagt attactggcg
    11821 ttcccccaca gcgaccaggc agtggtttgt ccataccagg tcatggtggt gtcagccgta
    11881 agtgaggagc ttttcgtatt gcctgattgt gcaagatatc ctgcgttcag attaccttcg
    11941 aaaggttttt tagcgctggc aggatcgtcc atgacagtaa aaacggaatc atcggcagct
    12001 gcattcagtg acgcaaacat gccccccgcc aacataacga tggcaggaac tgtcttcaaa
    12061 agcttcattt atcaagagtc cgtacaacaa aaaaagagac catcgcggtc ccggaaactt
    12121 tcttaaggat caaagattag cgtccctgga aaggtaacga attataaaaa ggcgcgaata
    12181 acttagcaat gtattcttat ttcatttttt gaataagcat gtggcgaaaa cagattttta
    12241 tttatatata tttatctgca aaattttaaa taaagctcta ataaatcata ttgttaattt
    12301 cttcactttc ggctgattcg gtgccagact gaaatcagcc tataggagga aatgatggta
    12361 cgtatctata cgttgacact tgcgccctct ctcgatagcg caacaattac cccgcaaatt
    12421 tatcccgaag gaaaactgcg ctgtaccgca ccggtgttcg aacccggggg cggcggcatc
    12481 aacgtcgccc gcgccattgc ccatcttgga ggcagtgcca cagcgatctt cccggcgggt
    12541 ggcgcgaccg gcgaacacct ggtttctctg ttggcggatg aaaatgtccc cgtcgctact
    12601 gtagaagcca aagactggac ccggcagaat ttacacgtac atgtggaagc aagcggtgag
    12661 cagtatcgtt ttgttatgcc aggcgcggca ttaaatgaag atgagtttcg ccagcttgaa
    12721 gagcaagttc tggaaattga atccggggcc atcctggtca taagcggaag cctgccgcca
    12781 ggtgtgaagc tggaaaaatt aacccaactg atttccgctg cgcaaaacca agggatccgc
    12841 tgcatcatcg acagttctgg cgaagcgtta agtgcagcac tggcgattgg taacatcgag
    12901 ttggttaagc ctaaccaaaa agaactcagt gcgctggtga atcgcgaact cacccagcca
    12961 gacgatgtcc gcaaagccgc gcaggaaatc gttaatagcg gcaaggccaa acgggttgtc
    13021 gtttcccttg gtccacaagg agcgctgggt gttgatagtg aaaactgcat tcaggtggtg
    13081 ccaccaccgg tgaaaagcca gagtaccgtt ggcgctggtg acagcatggt cggcgcgatg
    13141 acactgaaac tggcagaaaa tgcctctctt gaagagatgg tccgttttgg cgtagctgcg
    13201 gggagtgcag ccacactcaa tcagggaaca cgtctgtgct cccatgacga tacgcaaaaa
    13261 atttacgctt acctttcccg ctaacaaaaa cattccccca gcattggggg aatcaccacc
    13321 aacctgtcgg caacgcgttt ctccgactat gctcaaaagt catgtgataa caaaggggtg
    13381 aactatggcc agtggcgatc ttgtccgtta tgtcataacc gtcatgttgc atgaggatac
    13441 attgactgaa attaacgagt tgaataatta cctgactcgc gacggttttt tgctcaccat
    13501 gacggatgat gagggaaata tccatgagct ggggactaac acttttggac ttatcagtac
    13561 ccaaagtgaa gaagaaatta gagaactggt ttcggggctt acccaaagtg caaccggcaa
    13621 agatcctgaa atcaccatca cgacctggga ggaatggaat agcaacagaa aataaatggt
    13681 ttttgggcaa taatcagtct gtggtgtgcg ttagctcgtg tttttacacc gcattcttgc
    13741 gctaacctta tgatctggca gacaacatgg gagagacatc atgtggcagg caatcagtcg
    13801 tcttttgagc gagcagttag gtgaaggcga aatcgaactg cgtaatgaac tgcctggcgg
    13861 agaagtccat gccgcatggc atttgcgcta tgcaggacat gactttttcg tcaaatgtga
    13921 tgaaagggaa ctgcttcccg gttttaccgc cgaagccgac caactggagt tactgtcgcg
    13981 tagtaaaacc gtcaccgtgc ctaaggtttg ggcagtaggc gctgaccgtg actacagttt
    14041 tctggtgatg gattatctcc cacctcgtcc gctggatgcg catagcgcat ttattcttgg
    14101 tcagcaaatt gcgcgtttac atcaatggag tgaccaacca caatttggcc tcgattttga
    14161 taactcgctc tccacaactc cacagcccaa cacctggcaa cgtcgctggt caacgttttt
    14221 tgctgaacaa cggattggct ggcagttgga actggcagca gagaaaggga tcgctttcgg
    14281 caatatcgac gccatcgtcg agcatattca gcagcgtctg gcctcgcatc aaccgcagcc
    14341 ttctctgttg cacggcgatt tatggtccgg caactgtgcg ctgggtccgg atggcccgta
    14401 cattttcgac cctgcctgct actggggtga ccgagagtgc gacctggcga tgttaccgct
    14461 gcatactgaa cagccgccac aaatctatga cggctatcag tcagtatccc cgctacctgc
    14521 cgatttcctt gaacgtcaac cggtttacca actctacacg ctgttaaatc gtgcaagatt
    14581 atttggcggt cagcatttgg ttattgctca gcagtcattg gatagattat tagcagcatg
    14641 atatgggttg aggataatgg ccgctccgtg cggccttttg attaaataaa cccaagcaga
    14701 gaaaagaaca cataacctgc agcaatacaa ataaccggca ggatatatag tgagaaaaac
    14761 tgcaggaaaa tagtatggtg cggaacaaca atacgggact caatttgttc acgcgttagc
    14821 ccctcttccc ctttggcttt ttccagaatg agttgatctt caacaccttc ccgcaagaag
    14881 cgcgcctggc gactcatccg ggcaccggaa tcctgcaacg ccagtccgac aaaaatcagg
    14941 atgaaaatca cccagaacat aacgttcacg ccaccattaa aattaggggt cggggagtta
    15001 taccagaaca gattcaaaaa aggcgtattc gcctgcatca tatcgatcat gacatgagta
    15061 aagtcgagca tgaccgcatt aatgccttcc tggttttcct gccgggtatt cataaatttc
    15121 agcaaagaaa tcaatgtaga gatcaatgca ggtataaaaa tcacccaacc caaaatcctt
    15181 ttcaaaacag caatgcgtcc agcttgttga tacgtcatga gttctccttg attaagacgc
    15241 gtcgtttcac ttagtttacc tgtagatatc tgttttcgcc cattctttaa aggcgatatg
    15301 ataggcgctt aatcataagc acggcttaat accttacaca taatgctcta aaggagaggt
    15361 tgtaatgtca accccgcgtc agattcttgc tgcaattttt gatatggatg gattacttat
    15421 cgactcagaa cctttatggg atcgagccga actggatgtg atggcaagcc tgggggtgga
    15481 tatctcccgt cgtaacgagc tgccggacac cttaggttta cgcatcgata tggtggtcga
    15541 tctttggtac gcccggcaac cgtggaatgg gccaagccgt caggaagtag tagaacgggt
    15601 tattgcccgt gccatttcac tggttgaaga gacacgtcca ttattaccag gcgtgcgcga
    15661 agccgttgcg ttatgcaaag aacaaggttt attggtggga ctggcctccg cgtcaccact
    15721 acatatgctg gaaaaagtgt tgaccatgtt tgacttacgc gacagtttcg atgccctcgc
    15781 ctcggctgaa aaactgcctt acagcaagcc gcatccgcaa gtatatctcg actgcgcagc
    15841 aaaactgggc gttgacccac tgacctgcgt agcgctggaa gattcagtaa atggcatgat
    15901 cgcctctaaa gcagcccgca tgcgttccat tgtcgttcct gcgccagaag cgcaaaatga
    15961 tccacgtttt gtattagcaa acgtcaaact ctcatcgctg acagaactca ccgcaaaaga
    16021 ccttctcggt taatgaccag gggcagtgat ctcgctgccc ctggttcttt atctgaattt
    16081 gcattcaact gacggattaa tcgtcaattt aagagaaaga gttacaccgt caccacttcc
    16141 gtgcactgta taaaaatcct atactgtacg tatcgacagt ttagtgagtt ttatcatgac
    16201 ggcggaaggt caccttctct tttctattgc ttgtgcggta tttgccaaaa atgccgagct
    16261 gacgcccgtg ctggcacagg gtgactggtg gcatattgtc ccttccgcaa tcctgacgtg
    16321 tttgttaccg gacatcgatc acccaaagtc gtttcttggg cagcgattaa aatggatatc
    16381 aaaaccgatc gcccgcgctt ttgggcatcg tggttttacc cacagtctgc tggcggtatt
    16441 tgcgctgctg gcaacctttt accttaaggt tccggaaggc tggttcattc cggctgatgc
    16501 gctacaagga atggtgctgg gttatttgag ccacatactt gccgatatgc tgacacccgc
    16561 cggtgttccc ctgctctggc catgccgctg gcgtttccgc ttgcctatcc tagttcccca
    16621 aaagggcaac caactggaac gttttatctg catggcatta tttgtctggt cggtatggat
    16681 gccccattca ttacccgaga acagcgctgt tcgttggtca tcgcaaatga tcaatacctt
    16741 gcagatccag tttcatcggc ttattaagca tcaggttgaa tactaaaaag acaaaaatca
    16801 cctttctgga ataagcaatt ccatttgaat ataagagcca gctcacagtt ctgttaatct
    16861 tgcgccaaca ctatgactgc tacgcagtga tagaaataat aagatcagga gaacggggat
    16921 gaactttcca ttaattgcga acatcgtggt gttcgttgta ctgctgtttg cgctggctca
    16981 gacccgccat aaacagtgga gtctggcgaa aaaagtgctg gtgggtctgg tgatgggtgt
    17041 ggtttttggc cttgccctgc ataccattta tggttctgac agccaggtac ttaaagattc
    17101 tgtacagtgg tttaacatcg ttggtaacgg ctatgttcaa ctgctgcaaa tgatcgttat
    17161 gccgttagtc ttcgcctcta ttctgagcgc ggttgcccgt ctgcataacg catctcagtt
    17221 aggcaaaatc agttttctga ccatcggtac gcttttgttt accacgctga ttgcggcgct
    17281 ggtcggtgtg ctggtcacca acctgtttgg tttgacggct gaaggtctgg ttcagggtgg
    17341 tgcagaaact gcacgtctga acgccattga aagtaactat gttggtaaag tctctgatct
    17401 gagcgttccg cagctggtct tgtcctttat cccgaaaaac ccgtttgccg atcttaccgg
    17461 agccaatccg acgtcaatta tcagcgtggt aatttttgcc gcattcctcg gcgtagctgc
    17521 attgaaactg ctgaaggatg atgcgccgaa aggtgaacgc gtcttagccg ctatcgatac
    17581 cctacaaagc tgggtgatga aactggttcg ccttgtcatg caattgaccc cttacggcgt
    17641 tctggctcta atgaccaaag tggttgcagg ttctaacttg caagacatca tcaaactggg
    17701 aagtttcgtt gtcgcgtcct acctcggtct gctgattatg tttgcagtgc atggcattct
    17761 gctgggcatt aatggcgtga gtccgctgaa gtacttccgt aaggtatggc ctgtgctgac
    17821 gtttgccttt accagccgtt ccagtgctgc gtctatccca ctgaatgtgg aagcacaaac
    17881 gcgtcgtctg ggcgttcctg aatccatcgc cagtttcgcc gcctctttcg gtgcaaccat
    17941 tggtcagaac ggctgcgccg gtttgtatcc ggcaatgctg gcggtgatgg ttgcgcctac
    18001 ggttggcatt aacccgctgg acccgatgtg gattgcgacg ctggtcggta ttgttaccgt
    18061 tagttccgca ggcgttgccg gtgtcggtgg tggtgcaact ttcgccgcac tgattgtgct
    18121 gcctgcgatg ggcctgccag taaccctggt ggcgctgtta atctccgttg aaccgcttat
    18181 cgacatgggc cgtacggcgc taaacgttag tggctcgatg acagctggca cgctgaccag
    18241 ccagtggctg aagcaaaccg ataaagccat tctggatagc gaagacgacg ccgaactggc
    18301 acaccgttaa ttcttatgct ggcaacggtc cgttttgtat aggggccgtt gctttacttt
    18361 ttaaatgttc catcgcggcg atgcatactg actcatattt aaacagatcg tcagcgaaaa
    18421 aaatgtccaa cttatcaata cattcctggc tcaatgaatg tgcctgtagt gagaagctta
    18481 aaacctcata cccgagacgt tttctaagtg aactatctgg aatactcata atatcttcaa
    18541 gcacaccact tcccattccc ggaagattta gtggattaaa aagaagattg atattaagca
    18601 ttgatattat cgaaggaaac tttaggagac tctcattttt tttgaatcgc agcaaaaatg
    18661 ctcccggcag gatgtatata atttttttca tagtatatag tccttaaata atgaataacc
    18721 aacctatttt tatattgatc aaattcgtca ttttttcggg tcagaattca caggtaaaat
    18781 ccatcccaac aaaattctca ttaatatctc ttatccgaaa ctcactgcca taaagattat
    18841 taattatcac tctatattta acattgtcct gcagatacgt atcaaaacta agtgctggcg
    18901 ctcctggctt tgaggcatca tagttaatgt tagacatata ggcaatcata cgattgaagt
    18961 tcgactctgc tatttcatcg cagtcacatt gacccgttga tataaagaaa gtgagtgccg
    19021 ccatggtaga ctcaagcctt tctttaaaag agtcgaaagc caggctttta atatttaaat
    19081 caccataatt actctgtatt aagtttgtag aaaacatctc ccgccccata ttgttaacaa
    19141 aattattatc tcatttaaat ctaagtcact tacaatataa gtttaagagc gacgccacag
    19201 gatgaactat caaaaatagc tcatcatgat tagcaaaact taaccatttt aaaataaata
    19261 aacaattaaa gaaaaaagat cacttattta tagcaatagc tcgtcaaagg cagctttttg
    19321 ttacaggtgg tttgaatgaa tgtagcaacg aaatgcagaa tttcaggtca tgtaactccc
    19381 ggcaaaaccg ggaggtatgt aatccttact cagtcacttc cccttcctgg cggatctgat
    19441 ttgcccaacg ttgggcagat tcaggcacag taaacgccgg tgagcgcaga aatgactctc
    19501 ccatcagtac aaacgcaaca tatttgccac gcagcatcca gacatcacga aacgaatcca
    19561 tctttatcgc atgttctggc ggcgcgggtt ccgtgcgtgg gacatagcta ataatctggc
    19621 ggttttgctg gcggagcggt ttcttcatta ctggcttcac taaacgcata ttaaaaatta
    19681 gaaaaactgt agtttagccg atttagcccc tgtacgtccc gctttgcgtg tatttcataa
    19741 caccgtttcc agaatagtct ccgaagcggg atctggctgg tggtctatag ttagagagtt
    19801 ttttgaccaa aacagcggcc ctttcagtaa taaattaagg agacgagttc aatgtcgcaa
    19861 cataacgaaa agaacccaca tcagcaccag tcaccactac acgattccag cgaagcgaaa
    19921 ccggggatgg actcactggc acctgaggac ggatctcatc gtccagcggc tgaaccaaca
    19981 ccgccaggtg cacaacctac cgcccctggg agcctgaaag cccctgatac acgtaacgaa
    20041 aaacttaatt ctctggaaga cgtacgcaaa ggcagtgaaa attatgcgct gaccactaat
    20101 cagggcgtgc gcatcgccga tgatcaaaac tcactgcgtg ccggtaaccg tggtccaacg
    20161 ctgctggaag attttattct gcgcgagaaa atcacccact ttgaccatga gcgcatcccg
    20221 gaacgtattg ttcatgcacg cggatcagca gctcacggtt atttccagcc atataaaagc
    20281 ttaagcgata tcaccaaagc ggatttcctc tcagatccga acaaaatcac cccagtattt
    20341 gttaggttct ctaccgttca gggtggcgct ggctctgccg ataccgtgcg tgatatccgt
    20401 ggttttgcca ccaagttcta tactgaagag ggtatttttg acctcgttgg caataacacg
    20461 ccaatcttct ttatccagga tgcgcataaa ttccccgatt ttgttcatgc ggtaaaacca
    20521 gaaccgcact gggcaattcc acaagggcaa agtgcccacg atactttctg ggattatgtt
    20581 tctctgcaac ctgaaactct gcacaacgtg atgtgggcga tgtcggatcg cggcatcccc
    20641 cgcagttacc gcaccatgga aggcttcggt attcacacct tccgcctgat taatgccgaa
    20701 gggaaggcaa cgtttgtacg tttccactgg aaaccactgg caggtaaagc ctcactcgtt
    20761 tgggatgaag cacaaaaact caccggacgt gacccggact tccaccgccg cgagttgtgg
    20821 gaagccattg aagcaggcga ttttccggaa tacgaactgg gcttccagtt gattcctgaa
    20881 gaagatgaat tcaagttcga cttcgatctt ctcgatccaa ccaaactgat cccggaagaa
    20941 ctggtgcccg ttcagcgtgt cggcaaaatg gtgctcaatc gcaatccgga taacttcttt
    21001 gccgaaaacg aacaagcagc attccatcca ggtcatattg ttcctggtct ggacttcacc
    21061 aacgatccgc tgttgcaggg acgtttgttc tcctataccg atacacaaat cagtcgtctt
    21121 ggtgggccga atttccatga gattccgatt aaccgtccga cctgccctta ccacaacttc
    21181 cagcgtgatg gcatgcatcg tatggggatc gacactaacc cggcgaatta cgaaccgaac
    21241 tcgatcaacg ataactggcc gcgcgaaaca ccgccgggac cgaaacgcgg cggttttgaa
    21301 tcatatcagg aacgcgtgga aggaaataaa gttcgtgagc gcagtccatc gtttggcgaa
    21361 tattattccc atccgcgtct gttctggcta agtcagacgc cattcgagca gcgccatatt
    21421 gtcgatggtt tcagttttga gttaagcaaa gtcgttcgtc cgtatattcg tgagcgcgtt
    21481 gttgaccagc tggcgcatat tgatctcact ctggcccagg cggtggcgaa aaatctcggt
    21541 atcgaactga ctgacgacca gctgaatatc accccacctc cggacgtcaa cggtctgaaa
    21601 aaggatccat ccttaagttt gtacgccatt cctgacggtg atgtgaaagg tcgcgtggta
    21661 gcgattttac ttaatgatga agtgagatcg gcagaccttc tggccattct caaggccctg
    21721 aaggccaaag gcgttcatgc caaactgctc tactcccgaa tgggtgaagt gactgcggat
    21781 gacagtacgg tgttgcctat agccgctacc tttgccggtg caccttcgct gacggtcgat
    21841 gcggtcattg tcccttgcgg caatatcgcg gatatcgctg acaacggcga tgccaactac
    21901 tacctgatgg aagcctacaa acaccttaaa ccgattgcgc tggcgggaga cgcgcgcaag
    21961 tttaaagcaa caatcaaggt cgctgaccag ggtgaagaag ggattgtgga agctgacagc
    22021 gccgacggta gttttatgga tgaactgtta acgctgatgg cagcacaccg cgtgtggtca
    22081 cgcattccta agattgacaa aattccggcg taaatatgga taaggtcacg tcccctgggg
    22141 agtgacctta ccaccttact tacacattaa gataactacc caaccgataa ccacgctcag
    22201 caattgcata tttcaacgac gctgatgtca gcacttccag ctccgttaac cgtgggaaac
    22261 agtaagcact ctgacggata gtattatcga taaacgccgg atgacacatc acctccagcg
    22321 aacgatcacc ccgatggctt gcgtcatcca gcacttgcag gaacagtgcc tcgctaatct
    22381 cttcaccata aaacgcgcta ctgaatccct gagaactgcg cagattagcc ggtaaatcac
    22441 cagcgttaga tagcggctga cggtcgatgc gcaacgcaat cccctcttca gccgcaaacc
    22501 tggcaacaat cgggaaaatc tgcgggaaca tatgcacatg atgatggcta tcaagatgcg
    22561 taggtttgcg tccaaatagc tcaatgaaac gcaaatactg actggcaagc tcctgagtaa
    22621 tttcttccag cggtaaagca tcttcttctg ccaactgcca gatccatttt cccagcacac
    22681 catcgcgggt taaccccggc atagctgtca gtggcttgcc catagtaagg acaaagtgca
    22741 tccctatggc cagactcggt tcatcacgac tcaactgcac cgcatggtca atagcctgcc
    22801 cattcaccag cgccgtcgtt gatgtgacaa tcccattgcg acaggcctcg ataatgccgt
    22861 agttctgacc tttgcttaag ccaaaatcat cggcattaac aatcagtaag cgttccataa
    22921 tcagcctcgg ttaatgtgct tttttaagct ctgcgatgca gtcggcaaaa tttggcagcc
    22981 atttctcgtg cgccagaatc atctcgcgtg ccagcagctc agcatcgcga tcggaatgca
    23041 ccaacggact aaggtttagc gccagtaaca catcgttaaa ttctccgcta agtgcggcgt
    23101 tgctggcagc aatctcgaag cctttaatgg tgtgaatcag ccccatcact ttatcatcga
    23161 aatgcgtaat gcgcggatgt ggcgtcgcgc catcgcgccc cagcttacag gtcatttcta
    23221 ccgcccagtc tgccggaata ttatcaatat gcccatgatg cgggatatta acgtaatgtt
    23281 cagcttgctt gtcgttgtag atagcgttga tcacttcgca cgctgcatca gagtaataag
    23341 ccccaccgcg ctgttccagt tctttcggct taactttcaa ctccggattt ttatacagct
    23401 caaaaagttg tttctcgact ttctgtacta cctgtgctcg tgcgccgcct ttgtagtatt
    23461 cgcccatttc aatagccagc atctctttct gcttgaagta atacagcaga taagaacatg
    23521 gcagcagatt taacgaacga attaagccct cactaaatgg cagatcgaaa atatttttta
    23581 cagaggacgc ttttaactgc cctgacgcca caccatcaag caattcggca aagcgcgact
    23641 tgccatttac cagcacatcc ttaatgaaca ccatatggtt gaggccgaac agatcgatag
    23701 ataaatcatc gctgtctttc agcatcagaa catcgcgaat aaacatcttc atgccgatcg
    23761 gaatattaca cacgccgata aagcgtttaa atccggtatg acgataaacg gcttcagtga
    23821 ccattcccgc cgggttagtg aagttaatca cccatgcatt cggacaaagt tcttcgacat
    23881 cttttacgat gtcaaaaatc accggaatgg tacgcagacc tttaaacaga ccgcccgcgc
    23941 cgttggtttc ctgaccaaga taaccatgac ttaatggaat acgttcatcc agttcgcgcg
    24001 ccggtaattg gcctacgcgc agttgggtag taacgaaatc agcatctttc aatgcttcgc
    24061 ggcgatccag cgttttataa agcttcatcg ggacgccagc gttatcaatc atccgttggc
    24121 agagttcaaa aatgatatcc agtttctctt taccatcttc gacatccacc agccataatt
    24181 cgctgaccgg caattcgtga taacgcttaa taaatccttc cagtaactcc ggggtatagc
    24241 tgctcccgcc accaatagtg acgactttta atttctggct cataatttct cccttcagta
    24301 cagaatactg atatctggca tatctgcccc cccggacata aataatccag caacaggaca
    24361 gatatgtgaa ttgtcaggta taacgactta ctgattaaat tcagtcaatt tcttacgata
    24421 gctcttaggc gtaaaggacg ttaatttctt aaacgtttta ataaacaaac tcgggctact
    24481 ataaccggcc tcaaacgcaa tatccgtcac ggaatagttg gtcatttcca gttgtttttt
    24541 ggcaaaatta atacggatct cattaataat ctgcattggt gttttgccat agtatcgttg
    24601 agtcgctcgc gtcaaatatt cctgtgattt ggctgacaac gtcaccatat tctccagcgc
    24661 cgattcacta aactgctctt tatcatgcat cttttctacc gtacttttca gccactgcgg
    24721 tacatcatca atcacctgtt cttcgcggta atgacgtaaa cggttaatga cataaaaagt
    24781 aaccatctca acaaactctt ccagccctgt ttcgcggaaa ttcaatgaag aaatcactgt
    24841 ttccacatag gtgagaaaag cgttattggt ccggtatacc tgcgaagcga caaagcaata
    24901 aggcaacaac ggcaggtaat gctgctcaaa aaagcgttta ctgatcccaa cgttcaatat
    24961 acgcgtggca ccaaactcat aaaaactttg atggtgcgaa cctaacggaa taaaaacaaa
    25021 atcgccccgt tccagtaaca cgcgcttacc gttaatctcc tggaaataac gcccggttaa
    25081 taccagagta aattcataat agtcgtgctg atgcagcccg ctgatactct cagttttgtt
    25141 atagataaac acatggaagt ttttgccatt aaacaactgc tgttctcggg cagtggcaat
    25201 ttccggcgcg ttaatcactg gctgcatcat cgactcctta tgccttcagt ttttcatgaa
    25261 gctcaattaa ttcagtaatc agttcacgcg caagcatgga cgtcattaaa tgatcctgag
    25321 cgtggaccag caccagactc actttcatct taccttcgcc cgcatcgcct tcaatcagtt
    25381 tcgtctgtac cagatgcgct tcattcaatg ccatccgtga ctgatccatc atggcttttg
    25441 ctgcagcaaa atcgccctgc ttcgcctgtt tcagtgccgc atacgccagg ctgcgcgctt
    25501 gtccggagtt gatgataagc cccatcacca cttcttccag ctcttcagct tccgtttgcg
    25561 tatcgggaat gttatcgaga tccatcatac atcgttcctc tctattctta ccggcacgat
    25621 tacccgtacc ggcatcgatt aaaatttcag ggcattagcg atatcttctt cgctctcttc
    25681 tttatcaatc gcgttttgtg ctttgttagc caccacaaca aagggcagat aaattaacgt
    25741 tgcgatacca aggttgaaga gtgcgaccag caatgcggcg acgctaccgt tggtgttaaa
    25801 gaaggctccc agaccggttg gcatggtcca cggtgcaata ttggtcaccg gaggaatgat
    25861 gcccatgtag tacgctgcga gggtgattgc cgccagaatc ggttgtacca gtacaaacgg
    25921 gataaacatc accgggttca tgataattgg cagaccaaac agaatcggtt cgttaatctg
    25981 gaagatgccg gacggcagcg ccagttttgc cacctgacga taatcagcac ggcgagaggc
    26041 gataaagata gccaggatca ggcctaaagt cgcaccactg cccccaagga aaataaagga
    26101 gtccagcatc ggcttggccc agatatggaa ggtcttaccg gctgccagcg ccgcttcgac
    26161 ggaaccatat tgctgatagg tcgcgatatt ttccagcgcc cacggcgtca taatgccgtt
    26221 gtccagtgcg gtcagcgcca gcgcgccatg aataccgaag aaccagagca gtggaacaaa
    26281 gatcacatag gcccagccca ccacgctacc caacgatgcc agtggggttg agatggtatc
    26341 cataatgatc tgatggaagt tggtgcccca ggtattcaac gcccaggcaa taatccccat
    26401 cacggaaaga ataataaagc cgggaattaa tgccgagaag gaacgcgata ctgaagcagg
    26461 tacgctgtcg ggcagtttaa tgacccaatt gcggcggaca ataaaggtaa acatttctgc
    26521 caccaccagg ccaataataa tcccggagat gatattcgcc ccacctaacc agtttgcgcc
    26581 aaccgcatag gcctcaccga cactatatgg ggtgacggtc ataaatgctg caacggataa
    26641 caacccagcc gccagcgcat cgactttacg ctcttctgcc agcgccatgc caataaagaa
    26701 cggtgccatt aaagacatta tccctaatgt tccgttatat acgttgccgc caataccttt
    26761 cagaccatta agtgtttcaa tggttgaggc gtcgaggcga atacctaagg aataaaaaaa
    26821 cgacccctcc ccaaagctta gaaaaacgtt gttaattaat acaaacatgg cccccgcaag
    26881 ggttaacggc attaagcgaa taaagccatt tttgattgca ttaacgtgtg gctgctttcc
    26941 tattttaact gcaaaaggga ggagtacctt ttcaagcgat gcaataacat tactcataga
    27001 aaaataccct taaaaaccgc aatttaaata ttgcggtatt gatttatgaa ataactcttt
    27061 gacgggaaaa tttaaaataa attaatttgc tgcggctttt ttaatcgctg caaccgcagc
    27121 cttaagcacg cctaaaccat cgactttgcc ataaagcagc gagtcaatta cttcaaccgg
    27181 tttgttgggt aacaaacgct ggatttcggg caacatataa gcaatctgcg gccctaataa
    27241 cacgacatcg gcattctgac ctttttcacc agccagtgtt tccggaaatg cttcaataat
    27301 gaccggaact tcatattttt ctgcctgtgc gcgcattttt gataccagta aagaggtaga
    27361 catgcccgca gaacaaaaca gataaatgtg tttcttttcc ataaaactgc cctcatcgac
    27421 gattatctgt cagccagaca ctccgcaagc cttaacctgc ttccatgctc tgggtaactt
    27481 gcgaaaccaa catgactttt tttgtggctg aaaggagtat acggtataga cctgagcaat
    27541 agtatttctt tgaccttata aattgtttct ccttgacctg tggttatgac cctcttcaca
    27601 tttcgggcaa ataattcgcg aagataatta agaactcagg ccaaaaaaaa ccggcgcaat
    27661 ggccggtttc cgttgttact caagctttca gacgaattga ttacttcgca gcctgtggat
    27721 cagtgtcgta ttcagcacag gtctgataac cggagttgat gacatgtccg gtatcatcta
    27781 acgcgacaaa gtaggtttct gctttaccat cacgttgacc caggatgtag gtctggcaag
    27841 taccgcgagc atggatcatg ctcacttcag acgaaggttt acccgcaatt tgtgcaacct
    27901 gcgcccggct catgcctttt ttgacgtctt tcaccacagg ctgtacaaac tggtctttag
    27961 tacgatcata agccgtacaa cccgccagca tggttaatac cgccgctgca ctcagaattc
    28021 ctgccatatt cttgttcata ttccgtcctc ttgtttatca gcgtgttaga taagcctgga
    28081 atacattggg cgctttttca agcccgtgaa cgaaacagct ccgctttcag aggattcctg
    28141 tatgacgttt taaccaccat tcagcccgct gtcgcttgtc gtttcagtag caacgggtta
    28201 gctttaagga agttttgtct tttctgtctg gaggggttca atgacattgc aacaacaaat
    28261 aataaaggcg ctgggcgcaa aaccgcagat taatgctgaa gaggaaattc gtcgtagtgt
    28321 cgattttctg aaaagctacc tgcaaactta tccgttcatt aaatcactgg tgctcgggat
    28381 cagcggcggt caggactcca cgcttgccgg aaagctgtgc cagatggcga ttaatgagct
    28441 gcgccaggaa actggcaacg aatcactgca atttattgcc gtacgcctgc cctatggtgt
    28501 tcaggccgac gaacaagatt gccaggatgc cattgccttt attcaaccgg atcgcgtatt
    28561 aaccgttaat atcaagggcg cggtattggc tagcgagcag gcattgcggg aagcaggcat
    28621 tgaactgagc gattttgtcc gtggcaatga aaaagcgcgt gagcggatga aagcacaata
    28681 tagcattgcg ggtatgacca gcggtgtcgt ggtgggcacc gatcatgcag cagaagccat
    28741 taccggattc ttcactaaat atggtgacgg cggtacggat attaatccgc tgtatcgtct
    28801 caacaaacgc cagggtaaac agttgctgac ggcattaggt tgcccggaac acctttataa
    28861 gaaagcccca acggccgatc tggaagatga tcgcccttct ctgccagatg aagtggcact
    28921 cggcgtgacc tatgacaata tcgacgacta tctggaaggg aaaaacgtac ctgaacaggt
    28981 cgccagaaca atagagaact ggtatctgaa aaccgaacat aaacgccgtc cgccaattac
    29041 cgttttcgat gatttctgga aaaagtaata atttgcacct attggattgt gcgaaaaaga
    29101 gtaatttgtt cacgccggat gcggcgtgaa cgccttattc gacctacaaa actatgcaaa
    29161 ttcaatacat tgcaggagtc gaataggcct gacaggcgta gcacgtcaga cggtgtaacc
    29221 tttgtcatca acccgcctct tttttaatcg cctcccgcct gttacactgg atagataacc
    29281 agcattcgga gtcaacagtg gtacggcgtt taacttctcc gcggctcgaa tttgaagctg
    29341 cggcaattta tgaatatccc gaacatttac gttcattcct taatgactta cccacccgac
    29401 caggggtgta tctgtttcat ggcgaaagtg acaccatgcc gctctatatc ggcaaaagcg
    29461 ttaatatccg cagtcgggtg ctttctcatt tacgcacccc ggatgaagcc gccatgctac
    29521 ggcaatcccg gcgaattagc tggatctgca ccgcaggcga aatcggcgct ctgctccttg
    29581 aagcgcgatt aatcaaagaa caacagccgc tgtttaataa acggttgcgc cgcaatcgcc
    29641 aactctgtgc cctgcaatta aatgaaaagc gcgtcgatgt ggtgtatgcc aaagaggtgg
    29701 atttttcacg agcccccaac ctgtttggcc tgtttgccaa taggcgcgca gctttgcaag
    29761 cattgcagag catcgctgat gaacaaaaac tttgttatgg cctgttggga ctggaaccgt
    29821 taagtcgcgg tcgtgcatgt tttcgttcag cgctaaaacg ttgcgccgga gcatgctgcg
    29881 gtaaagagag ccatgaggaa catgcgctac gcttgcgcca gtctctggag cgtttgcggg
    29941 tggtgtgttg gccttggcaa ggtgcggtgg cactgaaaga acagcacccg gaaatgactc
    30001 aatatcatat tattcaaaac tggctgtggc tgggggcggt taattcgctg gaagaagcga
    30061 caacgttaat tcggacaccc gccgggtttg atcacgacgg ttataaaatt ctttgtaagc
    30121 cgctgctttc cggtaactat gaaattactg aacttgatcc ggcgaatgac cagcgagcca
    30181 gttgatttca ctgaacaaca gtttaccttg cggttgtaaa agccgcaggg tgtgcctgcc
    30241 atcgaaccag cacgcgccct ggtcggtagt gagcaattta tcgcccagtt gccacgcccc
    30301 gttaatcaca aacaccaccc cgccgcgtga gccaaaggta gtaaacgtac gttcggcaat
    30361 tctgactttc gccttacaga catccaggcg tgtcatgatg ttgaaatcca tcgacatctg
    30421 ccctgccgtc agtttcgctt ttaccacctg gtccgctgca aaggcaaaag gctgtaacgg
    30481 ttttaaggta tggttaaagc ggtctgcgct ttcaaggaac atctcgccgc cttccagcaa
    30541 cgtcactatc ctttccatgc cgggaaacaa agaaaactcc ccattcgccg cgatggatgc
    30601 aatgctggca cgccagtgaa aatcacgttt tgccggtggg aaagtgcaaa tttcgcgcgt
    30661 ttcaccggca gcgtttcgcc acagattcac cgacatttta cgcatatcaa agtattccat
    30721 actcgctccc ggcccgttct tttcattgtt atcgttcagg taaccgtgga tggttatcgg
    30781 caactcgggt gatttacgtt agtggtgatc aggctttttt tacaactgtt tgagaagaga
    30841 aaagaaaacc gccgatcctg tccaccgcat tactgcaagg tagtggacaa gaccggcggt
    30901 cttaagtttt ttggctgaaa gattattcag cagttgcagg cattttacct tttgccgctg
    30961 gacgttctgt cagacgcttc tcaaaattag cattaaattg ctttttctgt tccggcgtca
    31021 ggatgttgta aattttgttc tgggtttcca tgtgcgccag catgttagct ttgcgctgtt
    31081 cttccatttt tgcgatctgc gcttcagctt ttgctttatc gaaggtatcg ctggcaatga
    31141 tgtcatgcat tgcgcggcgt tcttccagcg gcggacgttt catctggtca cgctggcctt
    31201 tcatgatttc gcggatctgc tgtttctgcg cgtcggtcag gttcaggtct ttgaacatca
    31261 tgtcctgatg cggaccgaac ttgcctttgt ggtgcatcat cggcttcgcg tcagccggtg
    31321 ctgcggtagt ggtgtctgcg gcatgggcca ggttagccgc gccaagagcc agggtagagg
    31381 caacaaacag tgcagttaat ttacgcatat tctatatcct tcctttcagt tatttattac
    31441 ggctttctta agtagcgtgc cgtgttgacg agattaactt tactgacttt agcgtcaatt
    31501 aatcagagca acggtaaaac aatgaaagtg taaaaaacac ttttgcgcca attatggaga
    31561 aaaaaagaaa atttgatgga gagtgatgag agaataatac aacacgatga ttttgcagag
    31621 attatgaaga actataccgg atgactggtg ataaataaag caaataacca ggattaatct
    31681 gtattaattt ataagaaagc aacttaatac ccgcagaatg atttctgcgg gtaagtatta
    31741 gcttattttt tcgagcatta atcccgcgcg taatcccaac gctaccaacg gattagggaa
    31801 taacacatac tctacatcat gggttacggt aaaacgttcc tctccgtcct gcgccagcaa
    31861 tgttcctttc tcaaacggca taaaattcag cgtgtcactt gccatatgca tttcgaagga
    31921 cggcgagtgg cgagtaattt gcgaaaccac ccgataacgg agcggcggtg ttctcacgat
    31981 accgacactc tcaccagata gcagcgcagc aattgcgctg gcagttactg caaactggcg
    32041 aagatcgttt tgcccaaagg gcaacgcttt gccaagttcc agcgtacagg ccagcgcgcc
    32101 aaaatgtctg gcgctgaaat gggtaaacgt accaccaggt tcctgatgga acaccagcgc
    32161 ctccagcccc gccgcaccca gccacgtcag aaatttctcg tcccagggaa tgtcgcgttg
    32221 cggtaataca ccgaactgcg gatgcaagga gccacgaatt gcggtatgta gatcaaggtg
    32281 ccagcgcaca gattctttgc ccaggtcata aaaatcttcc aggcactgtt ccagttcgcg
    32341 cgcccgacag gtttctccgc tttcagcaaa tagctgccaa cgaccgccaa acattcgatt
    32401 catatcgcta tggcaataac gtttcccttg cttcagcgca ggaggattcc cgaggatcac
    32461 cagcaaccgc caacgtaacg ggatctcgcc gtgagatatc gcgccaagca acgcgtccag
    32521 catctccaca ggtgccgtct cattaccgtg tattcccgct gaaatcacca gtgcgccttg
    32581 cggtggcgtt aatggcgtca gttccagcac accatcgccc agccagcgcc agcgaacgcc
    32641 gttgatttct cgctcggtga taaccggttt tttacccgtt aaggtcagag caagaaaatt
    32701 atccattgcc ccctccctcg cgctggaacg gataaaccga accgagattc agtaattggc
    32761 tcaatacatc cagtgcttcc cgccctccgc gcagcaattg cgggtcggcc agatcggcag
    32821 cagtaaggcg atcgcggtag taacgatcca cccagtcatt gagcgcatta aacagcgtat
    32881 cgttcatcat caccgccgga ttcaccgccc ggcgttcttc ttctgtcaat accacccgca
    32941 accgcaggca cgccgggccg ccgccattcg ccatgctttc acgtaaatca aagactttta
    33001 gttcgctaat cgggttgtca gcggcaagga gttcattgag ataaccccat actccggcgt
    33061 gttcccgaca ctcctgaggc agcaccaaca tcatggaacc atcatcgcgg ctcaacagtt
    33121 ggctgttaaa cagataggta gacaccgcat ccgacacgga aacctgagtt gccggaactt
    33181 ctatcgccat aaaaccgttc acccgcgcac gcaggtttgc cagtaactgt gactggcgag
    33241 cgaacgcctg ttggtggcaa aacagcacct ggcggttact cacggcaatc acgtcattat
    33301 gaaaaacgcc ctggtcgata acgtccgggt tttgctgggc gaaaatcacc tgttggggat
    33361 tcacctgatt cagccttgcc accgcctcgc tggcttcgcg agtctgtcgc gccggataac
    33421 gggaaggccg ggtatcattg ccttcttctc gcccgtagac aaaaagttgc atacccggct
    33481 caccgtaatg accgccgaga cgattgtggt ttgccgcccc ctcatcaccg agcaacgcta
    33541 cctgcggcaa cgccgaatga acgctaaatt tctcttcgtc gttaaaaatc gcttttaaaa
    33601 gtgattcggt gacgtgcgct tccagcgagc ggtgaaattt attgttcagg ttggcaacgg
    33661 tgagatgcac tttgccatcc agcgtatcgg cagatggcgc gatcgttgcc gcattggcta
    33721 cccacattgg cgaagcggaa ctgacgctgg aaagccagtg cggtgcctgg cgtgcaactt
    33781 tttccagtac ctgctcatcg ctaccactga atcccaactg acgcagcacc ggaataaacg
    33841 gacgctcgtg cggcgggatc acggcctggg ggaatcccgc atcggcaagg gctttcattt
    33901 tcagtaagcc ctgttttgcc gcctgtcgcg ggttagacac ctgaaaacgg tgacgggtag
    33961 aggcttcatt accaaacgac aggccagcgt aatgatgcgt cagccctacc agcccgtcga
    34021 aattaacttc ccaggcgttc atcgcaccac ctcatcggaa aaatccagcc cggggttaag
    34081 cgttgcgggc aaagttaacg agtccgactc caggctcgcc ataggccatg cgcagtaatc
    34141 tgcggcatac caggcgctgg ggcgatggtt accggatgca ccaatgccgc cgaatggcgc
    34201 ggtactggca gcaccagtaa gcggtttgtt ccagttaaca atccccgccc gcgcctccag
    34261 caacagttga tcgaattttt cccgctcggg ggaaaccaga ccgcaagaga gtccgaagcg
    34321 agtgttattc gccattagaa tcgcttcctc gaaagaatca taacgccaga cgcgcaataa
    34381 cggtccgaac acctcttcat ctggtacgcc agcaacgcct gtcatttcaa tgatccccgg
    34441 cgtcagcaac gatgtctctg attgtaataa gcgcggcgca agcagggttc gtccgcccat
    34501 cgcttccagt tgctgccagg cagtaaccac ctgctgtgcg gcctgttcag aaatcagccc
    34561 gccaataaac ggctgcggtt cgtcatccca gttgcccggc gttaatcgct ggctgacggc
    34621 aaccagacga gcaagaaacg catcgccctg cgctccgctt ttgagcaata aacggcgggc
    34681 gcaggtgcag cgttgcccgg ctgtgacaaa cgccgactga atggtcagat ggacagccgc
    34741 gtcgatatcc gccacctcat cgataattag cggattatta ccgcccatct caagggcgag
    34801 aattttctcc ggctgaccgg agagctggcg atgcagctgg tagccggtat tggcgctacc
    34861 ggtaaacagc aaaccgtcga gatcctccag cgcactcagc gcctgacccg tttcacgccc
    34921 gccctgcacc aggttcagta cgcccggcgg caagccagcc tgctgccata aacgcattac
    34981 cgcttcgcca ctccacggtg tcagttcgct gggtttaaag ataatggtgt tacctgccag
    35041 caatgccgga acgatatgtc cgttcggcaa atgaccaggg aaattatacg gcccaaacac
    35101 cgccagcacg ccgtgcgggc gatgtcgcag gctcgccgca ccgtccggca tttcactacg
    35161 ctgctcgccg gtacgaacgt gatacgcctt aattgatatc gcgattttat tgatcatcgc
    35221 cgtcacttcg gttgccgctt cccagcgcgg cttacccgtt tctctggcaa taatcgcggt
    35281 taattcgcct ttattccttt ccagcaatcc ggcaaagcgt tcgacaacga cctgacgttc
    35341 agccaatgag agccgcgccc agcgcggaaa cgccgcacgg gctgcgcgac aagcctgccc
    35401 gacctgagcg gcatcggcat cattgccttg ccataacacc tcgcccgata ccggattacg
    35461 cttcacacgc gatgcgccct ggcccgttat ccagtcaccg ttaatccata aagtcatgct
    35521 gttttctcct ctgcgcacag gcgcaccaga cgaacgcgat cccctgcgtg gcatttgagg
    35581 gcatccagtt gtgcggcggt taaaatcaaa cgctcggttg ccggatcggt acgcgccagc
    35641 accacgcgga aatggtgata attttcattg gcgaccaggc aggccggaaa atcgccctgc
    35701 gcaggctgcc cttctgccac ttccaccagc cgacttttac gaatggcgcg cacgcggtcg
    35761 atgtcacact caagcgttgg cccgccgtcg aagatgtcga tatagttgcg gtaacgaaaa
    35821 ccttctttct ccagcaccgc gcgggcaggc gcggtttgcg gatgtacctg accgatgacg
    35881 tcctgggctt cctgggataa aaagtgggta tagatcggat gtttcggcat cagttctgca
    35941 ataaatgcct tttgcccggt gccgcagaga aaatcggcgc ggctaaaatc catcgaaaag
    36001 aagcgtttac cgaggctttg ccagaacggt gaatagccgt gttcgtcaat caccccgcgc
    36061 atttcagcaa ccactttgtc attaaacttg tcgcgaaaag ccgccataaa cataaagcgc
    36121 gatttcgaca gcaaatagcc gttgccctct ttgcgccagt ccgggtcgag aaacagcgtg
    36181 cacagctcgc tgctgccggt gtgatcgtta ctgagaaaca gcgtcggcaa tgcgttatag
    36241 acattcagct cttttgaggc gtgaaccaac gtgccgacgc gatagttgta ccagagatcg
    36301 ttcagcccaa ccgccacctc aatggcacaa atccccgcca cggtgcctgt ctcgctatct
    36361 tccagcacga acacatagcc ctgctcactt ttgggcagtt cgccttgcca ggttttgatt
    36421 gccctttcga tacgcgccga aagcgtggct tcattggcgg gaagcgacgt caggccgccg
    36481 cccgttttgc tggcaagctg catcagcgcc gagacatctg atcgctcaac gggacggatg
    36541 accatcatga tgaacctcgg ctaacaaagt gttcgcaagc agctgcaaag cgatccagtc
    36601 cggtcgtcac ctcttcttcg ctgacattga gcgcaggcgc aaaacgcacc acgttgccac
    36661 ccgcaatcag taccatcacg cctgctttcg ccgcttcctg agagatctgt ttcgcttgcc
    36721 cggcgtaatc ggcattcagt acacagccaa tcagcaaacc taagccgcga acttcactga
    36781 acaaaccata gcggtgatta atagtattaa gacgctcaac aaaccagtcg tgacgctgtt
    36841 taacgccatt aagcatctct ggtgtgttga tgagctccag cactttgcct gccaccgccg
    36901 aggccagcgg attaccgcca taggtggtgc catgagtgcc aacggtcatc acgcgggcgc
    36961 actcttcggt tgccaacaac gcaccgaccg ggaaaccgcc gcccagcgct ttggcggtag
    37021 ttaacagatc aggcgtcacg ccgtagtgca tataggcata cagttccccg gtgcgcccga
    37081 cgccggtttg tacttcatca aaaatcaaca gcgcattgtg gcggttacac aattcacgca
    37141 gaccttgtaa aaacgcgttg ctggctggca ccacaccgcc ttccccctgg atgggttcga
    37201 caatcaccgc acaggtagag tcgtcaatca gcgcgctggc agagttaata tcgttatatg
    37261 cagcatgacg aatatccgcc ggcagtggcg caaaatcctg tgaataggct ggctgcccac
    37321 ccgcactgac agtaaacagc gtgcgaccat gaaacgcatt tttgaacgcc acgatgccgc
    37381 tcttatggct gccgtagcgg tcgtgagcga atttacgcgc cagttttagc gccgcttcgt
    37441 tggcttccgc accggagtta caaaagaaga cgcgatcggc aaacgtggcg tcgatcaatt
    37501 ttttcgccag tcgcagtacc ggctcgttgg tgtaaccgtt gccggtatgc cagaacttac
    37561 tcgcctgttc gttcagcgct tcacgcagtt ccggatgcgc atggcccagc gcgttcaccg
    37621 caatgccacc cgcgaagtcg atatactctt tcccctgctg atcccacaag cgcgaacctt
    37681 cgccacgtac cggtataaag ggtgccggag cgtaaacagg tatcatccat tcatcaaagt
    37741 tttcacgcgt aattggctga gacatagcga cctctacagt aaataattcg ttatttatat
    37801 gttaacaata agtaatgttt gcgctgtaaa tgtagattgc agggttcgtg ccagccagtg
    37861 ataaaagtgc ataaacggcg gaggctaact ggaaatcaag gagttataac caaaccatat
    37921 gcatttaaag tgcatataaa gtgaatacgt ttgcgatgtg ggtgaataaa aagaataaaa
    37981 aacgcaatgt tatgcagaag taaaatataa ttctggaatt gtgatcattg acgaaattta
    38041 ctggaaatta ctgcgccatt ctgacgcagc gcgcaccaaa agcgggcatt ttttgcgcca
    38101 tcgttgacat cattaacaac catcgatcaa atcacttaac aacaggcggt aagcaacgcg
    38161 aaattctgct accatccacg cactctttat ctgaataaat ggcagcgact atgaaatttg
    38221 tctcttttaa tatcaacggc ctgcgcgcca gacctcacca gcttgaagcc atcgtcgaaa
    38281 agcaccaacc ggatgtgatt ggcctgcagg agacaaaagt tcatgacgat atgtttccgc
    38341 tcgaagaggt ggcgaagctc ggctacaacg tgttttatca cgggcagaaa ggccattatg
    38401 gcgtggcgct gctgaccaaa gagacgccga ttgccgtgcg tcgcggcttt cccggtgacg
    38461 acgaagaggc gcagcggcgg attattatgg cggaaatccc ctcactgctg ggtaatgtca
    38521 ccgtgatcaa cggttacttc ccgcagggtg aaagccgcga ccatccgata aaattcccgg
    38581 caaaagcgca gttttatcag aatctgcaaa actacctgga aaccgaactc aaacgtgata
    38641 atccggtact gattatgggc gatatgaata tcagccctac agatctggat atcggcattg
    38701 gcgaagaaaa ccgtaagcgc tggctgcgta ccggtaaatg ctctttcctg ccggaagagc
    38761 gcgaatggat ggacaggctg atgagctggg ggttggtcga taccttccgc catgctaatc
    38821 cgcaaacagc agatcgtttc tcatggtttg attaccgctc aaaaggtttt gacgataacc
    38881 gtggtctgcg catcgacctg ctgctcgcca gccaaccgct ggcagaatgt tgcgtagaaa
    38941 ccggcatcga ctatgaaatt cgcagcatgg aaaaaccgtc cgatcacgcc cccgtctggg
    39001 cgaccttccg ccgctaattt agcagctctc ctggctcaaa ctgggtcagg agaattaacc
    39061 ttgagaaaaa tcaacaaact gtcagtaatg atttgttgcc tgccgtcctt tgttataccg
    39121 tcactgcgtt tttagttgtc tgaccacttc tctattatca agtttgatat aggaaactcc
    39181 acgatgaacg ctgagcgtaa ctttctgttt gcctgtctta tttttgcgct ggtcatttac
    39241 gctatccacg ctttcggttt attcgatctg ctcaccgatt taccccactt acagacactc
    39301 attcgccaga gcggattgtt cggttatagc ctctatattc tgttattcat cattgccacc
    39361 ctctttctgt taccaggaag catactggtg atcgctggag gaatagtttt tggcccgctc
    39421 ttagggacac tactctcatt aattgccgcc acgctggcct cctcgagctc attcctgctg
    39481 gcgcgctggc tgggacgtga tttactgctg aaatacgtgg gccatagcca taccttccag
    39541 gccattgaaa aaggcattgc gcgtaacggt attgattttc ttattctgac ccgcttaatc
    39601 ccgttgtttc cttacaatat tcaaaattac gcttacggat taaccaccat cgccttctgg
    39661 ccttataccc ttatttcggc actcacgacc ctgcccggta ttgttattta taccgtgatg
    39721 gcaagcgatc tcgccagtga aggcattacg ctgcgcttta ttttacaact ctgtctggcg
    39781 ggcctggcgc tgtttattct cgtccagctc gcaaaactct acgcccgaca caaacatgtg
    39841 gatctgtctg cttcgcgccg cagcccactt actcacccaa aaaatgaagg atagaacgat
    39901 gtcgcaacat tattcagtgt catggaaaaa aggactggct gcactctgct tactggctgt
    39961 tgccgggctt agcggctgcg atcaaaaaga gaatgcggcg gcaaaagtgg aatacgacgg
    40021 actttcgaac agccaaccgc tgcgcgtcga tgccaataac catacggtaa ccatgctggt
    40081 gcaaattaat ggtcgtttcc tcaccgacgt cactcgtcac ggtattgtgt ttaaagatgg
    40141 ctccaacgga cataaatcgc tgtttatggc ttatgcgacc ccgaaagcat tttatgaagc
    40201 cctgaaagag gcaggtggta cgccgggcga aaatatgacg atggataata aagaaacgac
    40261 tcttgtcaca ggcagcaaac tggatatttc ggtcaactgg caaggggcgg caaaagcgta
    40321 ttccttcgat gaagtgattg ttgacagtaa tggcaagaaa ctggacatgc gctttggcgg
    40381 taatttaacg gcagcagaag agaagaaaac gggttgcctg gtgtgtctgg atagctgccc
    40441 ggtcggcatc gtcagcaatg caacatacac ttatggtgcg gtggaaaaac gcggcgaagt
    40501 gaaattcaaa ggcaatgcct cagttctccc ggcggataac acgctggcaa cggttacctt
    40561 taaaatcacc gaataaagcc aggataaagg atgatgaaga tacaatcgcg taaaatctgg
    40621 tactaccgta taaccctcat catcctgttg ttcgctatgc tgctcgcatg ggcgctgctt
    40681 cccggcgtcc atgagtttat caatcgcagc gttgcggcgt ttgccgccgt ggaccaacag
    40741 ggtatagaac gctttattca gtcttacggc gcactggcgg cagttgtctc gttcttgttg
    40801 atgattttac aggccattgc tgcaccgcta cctgcgtttt tgatcacctt tgccaatgcg
    40861 tcgctgtttg gcgcgttctg gggcggcttg ctgtcgtgga ccagttcgat ggccggcgcg
    40921 gcgctgtgct tttttatcgc cagagtgatg ggccgcgaag tggtggaaaa attaaccggc
    40981 aaaaccgtgc ttgacagtat ggacggcttt ttcactcgct acggcaaaca caccatcctg
    41041 gtctgtcggt tattgccttt tgtccctttc gatccaatca gctatgctgc cggtctgact
    41101 tcaatacgtt ttcgctcgtt ttttatcgcc accgggcttg gtcaattacc ggcgactatt
    41161 gtttattcct gggcgggcag catgttaaca ggcggtactt tctggtttgt caccggactg
    41221 tttattctgt ttgccctgac cgtggtgatt tttatggcga agaaaatatg gcttgagcgc
    41281 cagaagagga atgactgatg ggtttaccgc cgcttagcaa aattcctttc attttacgtc
    41341 cgcaggcgtg gctgcatcgt cgccattacg gcgaggtgct aagcccgatt cgctggtggg
    41401 ggcggatccc gtttatcttt tatttggtgt caatgtttgt tgggtggctg gagcgcaaac
    41461 gctcaccgct cgatccggta gtgcgatcgc ttgtcagcgc gcgcattgcg caaatgtgcc
    41521 tgtgtgagtt ttgcgtggat atcaccagta tgaaagtcgc cgagcgtacc ggcagcaacg
    41581 ataaactgct ggcagtggct gactggcggc aaagcccgct ctttagcgat gaagaacggc
    41641 tggcgctgga gtacgccgaa gccgcaagcg tcacaccgcc aacagtcgat gatgccctgc
    41701 gtacccgact ggctgcgcat tttgacgctc aggcgctcac cgaactgacg gcattgatcg
    41761 gcctgcaaaa cctgtcggct cgttttaatt ctgccatgga cattcccgct caggggctgt
    41821 gccgtattcc ggaaaaacgt tcttaaggag ggaagatgcg ccattgtggg tggttgctgg
    41881 gattgttatc gctgttttct ttggcaacac atgccagtga ctggcaggaa attaaaaatg
    41941 aggccaaagg gcaaaccgtc tggtttaacg cctggggcgg cgataccgca attaaccgct
    42001 atctcgactg ggttagcggc gagatgaaaa cccattacgc tataaacctg aagattgttc
    42061 gtctcgcgga tgccgcagac gcggtgaagc gcattcagac cgaagctgct gccggacgta
    42121 aaacgggcgg ctcggtggat ctgctctggg tgaacggcga aaacttccgc accttaaaag
    42181 aggccaattt attacaaacg ggctgggcgg agactctgcc caactggcgc tatgtcgaca
    42241 cacagctgcc ggtgcgggaa gatttttcag tgccgacaca aggtgcggaa tcgccctggg
    42301 gcggcgcaca actgacgttt atcgcccgcc gcgatgttac gccacagcca ccacaaacgc
    42361 cgcaagcctt actggagttt gctaaagtca atcccggcac ggttacttat ccgcgcccac
    42421 cggactttac cggcacggcg tttcttgaac agttgctgat tatgctgacg ccagatcccg
    42481 ccgcattaaa agaagcgccg gacgatgcga ctttcgcccg tgtcactgct cccttgtggc
    42541 aatatcttga tgcgctacat ccgtatttgt ggcgcgaagg aaaggatttc ccgccttcgc
    42601 ccgcgcggat ggatgctctg ctgaaagccg gcacattgcg cctgtcgctg acctttagcc
    42661 ccgcgcatgc gcagcaaaaa atcgccagcg gcgatttgcc ggcaagcagt tacagttttg
    42721 gctttcgcga ggggatgata ggcaacgtgc atttcgtcac cattccagcc aacgcgaatg
    42781 ccagtgctgc ggcgaaggta gttgccaatt tcctgctctc acccgatgcg caactgcgta
    42841 aagcagatcc cgttgtctgg ggcgatcctt ctgttctcga tccgcaaaaa ctgcctgacg
    42901 ggcagcgcga aatattgcaa tcaagaatgc cgcaggatct gccgccggta ctggctgaac
    42961 cgcacgcagg atgggtgaat gcactggaac aagaatggtt acgccgttac ggtacgcatt
    43021 aatctttttg ctgtgggcga tggtggcggt gatttatgca ccgctgatcc cggcagctct
    43081 cacgctgata tcgcctgcgt tgtcgttgac acactggcag gcgttatttg ccgatccaca
    43141 gttaccgcat gcattactgg caacgctggt gtcgacaacc atcgcggcgg tcggggcatt
    43201 gttgattgcc ctgctggtga ttgtggcgct atggcctggg ccgaaatggc agcgtatgtg
    43261 cgcccgtctg ccgtggctgc tcgccattcc ccatgtggct tttgccacca gcgccctgct
    43321 gctctttgct gacggagggc tgctatatga ctatttcccg tatttcactc cgccaatgga
    43381 ccgatttggc atcggtctgg gcctcaccct tgcagtgaaa gaaagcgcat ttctgctgtg
    43441 gatcttagcg gcagtattga gcgaaaaacg gctgttgcag caggtcattg tgctggattc
    43501 gctgggctac agccgctggc aatgcctgaa ctggctgctg ttgccctccg tcgcgccttc
    43561 gctggcaatg gcgatgctgg cgattgttgc ctggtcgctt tcggtcgtgg atgtggcgat
    43621 tattcttggg ccaggtaatc caccgacgct ggcagtaatt agctggcagt ggttaactca
    43681 gggcgacgcg gatcaacaaa cgaaaggcgc actcgccagt ctgctgctga tgctgttact
    43741 cgccgcctac gttttgctga gctatctgct atggcgcagc tggcggcgca ctattccccg
    43801 cgtagatggc attcgcaagc ctgccacacc tttattacca ggcactacgc tggcgagttt
    43861 tttaccctta accggtgtgc tgtgtgtggt tctgctggcg atcctcgcgg atcagtcgac
    43921 gatcaatagt gaagcactca tcaacagcct gacaatgggg ctggtggcga cattcatcgc
    43981 tttgctcctg ttactgctgt ggctggaatg ggggccacag cgtcgccagt tgtggctctg
    44041 gttgcccatt ctattgcccg ctctgccact ggtggcgggc cagtacacgc tggcgctatg
    44101 gctgaacctg gatggaagct ggacggcggt ggtctggggg catctgctgt gggtaatgcc
    44161 gtggatgctg tttatcctgc aacccgcctg gcagcgcatt gattcacggt taattttgat
    44221 tgcgcaaaca ctgggctggt cgcgggccaa aatcttcttt tacgtgaaat gcccactcat
    44281 gttgcgccct gtgctgattg ccttcgcggt gggattttca gtcagtattg cgcagtatat
    44341 gccgacgctg tggctgggcg cggggcgttt tccgacgctc accactgagg cggtggcatt
    44401 aagcagcggc ggcagcaacg gtattctcgc cgcccaggct ttatggcaac tgttgttacc
    44461 gcttattatt tttgccctga ccgcgttagt cgcaaaatgg gtaggttatg tcagacaagg
    44521 actccgctaa tgctctgcgt gaaaaatgtt tcgctacgtt taccagaaag ccgcttgctg
    44581 acaaacgtta actttacggt ggataaaggt gacattgtca cgttaatggg gccgtctggc
    44641 tgtggaaaat ccactctgtt ttcatggatg attggtgcac tggctggaca gttttcttgt
    44701 acaggtgagc tatggttcaa tgagcaacgg attgacatgc tacccaccgc acagcgtcag
    44761 attggcattc ttttccagga tgcactgtta tttgaccagt tcagcgtcgg gcaaaattta
    44821 ctgctggcgc taccgtcgac gctcaagggg actgccaggc gcaatgccgt gaaagacgcg
    44881 cttgatcgag cgggactggc tgaaacttat caccaggacc ctgcgacatt atcaggcggt
    44941 cagcgagcgc gggtggccct gctgcgcgcc cttctcgctc agccaaaagc gttactcctg
    45001 gatgagccat tcagccgtct tgatgtggct ctgcgcgata attttcgcca gtgggtgttc
    45061 agcgaagttc gcgaactggc gatccccgtc gttcaggtaa cgcacgatct ccaggatgtt
    45121 cctgctgata gttctgttct ggatatggcg cagtggtcag aaaattacaa caaactgcga
    45181 taacgcaaag tttttctcaa tgcgtcagtt cagaatggcg cactcaaaac tacaatgtcg
    45241 ggattttcga tgaaacgtgt ttctcaaatg accgcgctgg caatggcttt agggctggct
    45301 tgcgcttctt cgtgggccgc tgaactggcg aagcctctta cacttgacca gcttcaacaa
    45361 caaaatggca aagcgataga tactcgcccc agcgcgtttt ataacggctg gccacaaacc
    45421 ttaaatggcc cttctggtca tgaacctgcc gccttaaacc tctctgccag ctggctcgac
    45481 aaaatgagca ccgaacagct ctatgagtgg atcaagcaac ataatctgaa aaccgatgct
    45541 ccggtggcgc tgtacggcaa tgacaaagat gtcgacgccg tcaaaacgcg tctgcaaaaa
    45601 gcaggtttta cgcatatctc cattctgagt gacgcgctaa gcgaaccttc ccgtctacaa
    45661 aaactgccgc actttgagca gctggtttat ccgcaatggc tgcacgacct gcaacaaggt
    45721 aaagaggtta cggcgaaacc tgccggtgac tggaaagtca ttgaagcggc ctggggcgct
    45781 cctaagcttt accttatcag ccatattcct ggcgctgact acatcgatac caacgaagtg
    45841 gaaagcgaac cgctgtggaa caaagtttct gatgaacaac taaaagcgat gctggcaaaa
    45901 cacggcattc gccatgacac cacggtcatt ctgtacgggc gtgacgtata cgctggagcg
    45961 cgtgtggcgc aaattatgct ctacgcaggc gtgaaagatg tgcgtctgct ggatggcggc
    46021 tggcaaacct ggtccgacgc gggactgcct gttgagcgag gaacgccacc gaaagtgaaa
    46081 gcggaaccgg atttcggcgt gaagatcccg gcacaaccgc agttgatgct cgatatggaa
    46141 caggcccgtg gactgctgca tcgccaggat gcatcgctgg tgagcattcg ttcgtggaca
    46201 gaatttatcg gtacgaccag cggttacagc tatattaaac caaaaggtga aatagccgga
    46261 gcacgttggg gacacgctgg tagcgactcg acgcatatgg aagattttca taacccggat
    46321 ggcaccatgc gcagcgccga tgatattacc gctatgtgga aagcgtggaa tatcaaacca
    46381 gagcagcaag tttcattcta ctgcggcacc ggctggcgcg cgtccgaaac ctttatgtac
    46441 gcacgcgcca tgggttggaa gaatgtttcc gtgtatgacg gcggctggta cgaatggagc
    46501 agcgatccaa aaaatccggt agcaaccggt gaacgcggcc cggacagtag caaataacat
    46561 tgcaattact gacgctggag cgacttcagc gtcagatacc cactccacac ccgcgtaaag
    46621 gtcgtcatcc agcacaacgc accgaagatc cacgcaaacc acgcaaacca tgcagggaat
    46681 aaacatccca gcacaaacag taagatcgtt tctgtgcctt cggttaatcc ccccagatag
    46741 taaaacgact tatgtgcata accggggtta tcaatctgat gttttgctgc cagtgcagca
    46801 aaggcgagaa aactgctgcc cgtgccgata aacgcaaaca acaaccagcc gcctgccagc
    46861 gcattttgct ccggtgcagc aagaataaag ccaaacggca ccagcgcgta aaagagaaaa
    46921 tcgagagaaa tatcaagaaa gccgcccgcg tcggtaagct ctctgcgccg cgccagcgca
    46981 ccgtccagac catcaagcag cctgttcaac aaaatgacga ctagcgccgc cagataccag
    47041 cccagcgcca gaaacggcag agccagcacg ccgatggcaa atcccactaa tgttaaacca
    47101 tctggcgtaa tgcccggttt atcaagaacc cgcacgcact gatgcaacaa cggtttaatc
    47161 cggggatgaa gatggcggtc tagcacaggc actccttaaa tataaagcct ttctgattga
    47221 gcaacagtgc ggatattatg gcatttttcg cttatctgcc cgtgtgtaat ttatgaaaat
    47281 gattgaagtt gttgccgcca tcattgaacg tgatggcaaa attttactcg cgcaacgccc
    47341 cgcccagagc gatcaggcgg gattatggga gtttgccggt ggtaaagtcg agctggatga
    47401 aagccagcag caggcactgg tgcgtgagtt aaacgaagaa ttgggcatcg aagcaactgt
    47461 gggtgagtat gttgccagcc atcagcgaga agtttcgggc cggattatcc atcttcatgc
    47521 ctggcacgta cccgacttcc acgggacgtt acaggcacat gaacatcagg cgctggtctg
    47581 gtgctcacct gaagaggcgc tgcaatatcc gctggcccct gctgacattc cactattaga
    47641 ggcgtttatg gctttacgcg ccgccagagc agcggattag tgctaagggt tttgtcatcc
    47701 cgctggcatt gcagcagtat tccttcggct ttaattaccg ccccttcaga ataattttga
    47761 tcctgataaa cgcagcactg agtacagggc tgcgctgact gcccgcctga actgaacact
    47821 tctggcggta cgtttacctc cacgtccgga cgataatgcg ggttagccag tgcaattaat
    47881 ggaaatgcta atactacggc gaacaatgct cgactcacag ggaactcctt aacgttattg
    47941 tctctgctac tgataacggt agccgggtgg caaaacttta gcgtctgagt tatcgcattt
    48001 ggttatgaga ttactctcgt tattaatttg ctttcctggg tcattttttt cttgcttacc
    48061 gtcacattct tgatggtata gtcgaaaact gcaaaagcac atcacataaa caacataagc
    48121 acaatcgtat taatatataa gggttttata tctatggatc agacatattc tctggagtca
    48181 ttcctcaacc atgtccaaaa gcgcgacccg aatcaaaccg agttcgcgca agccgttcgt
    48241 gaagtaatga ccacactctg gccttttctt gaacaaaatc caaaatatcg ccagatgtca
    48301 ttactggagc gtctggttga accggagcgc gtgatccagt ttcgcgtggt atgggttgat
    48361 gatcgcaatc aggtacaggt caaccgtgca tggcgtgtgc agttcagctc tgccatcggc
    48421 ccgtacaaag gcggtatgcg cttccatccg tcagttaacc tctccattct caaattcctc
    48481 ggcttcgaac aaaccttcaa aaatgccctg actaccctgc cgatgggcgg tggtaaaggc
    48541 ggtagcgatt ttgacccgaa aggtaaaagc gaaggcgaag tgatgcgttt ctgccaggcg
    48601 ctgatgaccg agctttatcg tcatctgggc gcggataccg acgttccggc aggtgatatc
    48661 ggcgttggtg gtcgtgaagt cggctttatg gcggggatga tgaaaaagct ctccaacaat
    48721 accgcctgcg tcttcaccgg taagggcctt tcatttggcg gtagtcttat tcgcccggaa
    48781 gctaccggct acggtctggt ttatttcaca gaagcaatgt taaaacgcca cggtatgggt
    48841 tttgaaggga tgcgcgtttc cgtttctggc tccggcaacg tcgcccagta cgctatcgaa
    48901 aaagcgatgg aatttggtgc tcgtgtgatc actgcgtcag actccagcgg cactgtagtt
    48961 gatgaaagcg gattcacgaa agagaaactg gcacgtctta tcgaaatcaa agccagccgc
    49021 gatggtcgag tggcagatta cgccaaagaa tttggtctgg tctatctcga aggccaacag
    49081 ccgtggtctg taccggttga tatcgccctg ccttgcgcca cccagaacga actggatgtt
    49141 gacgccgcgc atcagcttat cgccaatggc gttaaagccg tcgctgaagg ggcaaatatg
    49201 ccgaccacca tcgaagcgac tgaactgttc cagcaggcag gcgtactgtt tgcaccgggt
    49261 aaagcggcta atgctggcgg tgtagcaacg tcgggcctgg aaatggcaca aaacgctgcg
    49321 cgcctgggct ggaaagccga gaaagttgac gcacgtttgc atcacatcat gctggatatc
    49381 caccatgcct gtgttgagca tggtggtgaa ggtgagcaaa ccaactacgt gcagggcgcg
    49441 aacattgccg gttttgtgaa ggttgccgat gcgatgctgg cgcagggtgt gatttaagtt
    49501 gtaaatgcct gatggcgcta cgcttatcag gcatacaaat gggcacaatt cattgcagtt
    49561 acgctctaat gtaggccggg caagcgcagc gcccccggca aaatttcagg cgtttatgag
    49621 tatttaacgg atgatgctcc ccagggaaca tttcttatgg gccaacggca tttcttactg
    49681 tagtgctccc aaaactgctt gtcgtaacga taacacgctt caagttcagc atccgttaac
    49741 tttctgcgat agcagcagat atgcctgtaa agaaatccca ttagactatt tttttgataa
    49801 tcttcttcgc tttcgaacaa ctcgtgcgcc tttcgagaag caagcattat ataatgccag
    49861 gccagttctt ctccaattgt cccgttttga aaagctgtgc ttgatatcga gatcatccat
    49921 gataattccg ccgcccatat tagcttcgcc gaggatttac cggagcgatt attagcgcaa
    49981 tcagagatat agtctgaggg aaaaacagca aatttattca acaaggcgat aacctgctct
    50041 ggggcttcct ccatgtttgc tttaaaggta ttggctccat ggtcgccaga aagaaaatgc
    50101 tccattaagg cacaataact ttcgctatct tcgatacccc attgatcctc taaagactcg
    50161 cgtcttttac ttatgatatc gatcgagtca aaaggaagca catgatattg gaaggtatct
    50221 ttgccaggtt caggctttcg cggccagaac tccagcgttt cagaccattg cttatgatag
    50281 aatcgataag gtgcgatcaa ttgtagcgcc tgtaacttct cgatactgag cggctcaata
    50341 cctttagcct gataataatg cagttgttct ttttttgctt taaaaccggc ccgaacaata
    50401 agccccatca taattaatag ataaagaaaa gagcatcccg cagtaatcag gcctctttca
    50461 ttcaaaccgt tggatgttat cgctgcgaat acaaacatta cagcgacaac acatgttaaa
    50521 tacccccccc cacttacaaa gcagcatggc cttattttct ttaatcatcc gttcaaaatt
    50581 actattaaat atttcccagc cattaaaaga atacttctcg ctcccaggat ggttttgtaa
    50641 taaaactttt ttcatcacat tccctgttat tacatacttt agaggcgata attttatcca
    50701 tgcaaaaaaa atatccaacg aattttcttg atccgctgga tatttcagaa tatgactcga
    50761 atagcacgaa agattcgctc gcttacgcta tcgccccgct tccggcttca tctgctggcg
    50821 gactattttt cgcactacgt ttacgcggtg cagccttttt cttatcagca ctgccaccac
    50881 tgcccggagc cacaatgccg cgaaactgcc gcaccggcgt acgtttggct tgatcaataa
    50941 gctgatatag cgtccccacc agcggctgca taaagtcctg atagcgacac tgcttttcgc
    51001 tgatttgcgt cagcaccgat tcccagtgcg cggtcatgtc cggtcgcgta gccatttctg
    51061 gcagcgaatg gaataacgct tttccggcgt cggtggagtg gatatagcgc ccttttttgg
    51121 tgaggaaacc acgcttgaac aacagttcaa taatcccggc acgcgttgct tctgtcccca
    51181 gaccatcggt cgcacgaagg atctttttca gatctttgtc ctgcacaaag cgcgcaatcc
    51241 cggtcatcgc cgaaagcagt gttgcatcgg taaaatggcg cggcggctgg gtttgccgct
    51301 ctaccacttc acctttttca cacagcaact catcgccttt cgccaccaca ggcaatggcg
    51361 tgccgtcgtt ttcttcatcg cgctctttgc tgcctaacag cgcgcgccaa cctgcttcag
    51421 caagaaaacg cgctttagcg acaaatttgc ctttggcaat gtccagttcg ataacacact
    51481 tgcggaacac tgcatccggg cagaactgca tcagatactg acgggcaatc aggttataga
    51541 ccttcgcttc gttctccgtc aggttgatcg cagaactcct tgcggtcgga atgatggcgt
    51601 ggtgcgcatc gacctttttg tcatcccaac agcggttgcg tatatctgga tctaccactg
    51661 gctgcggcaa cagatctggt gcatgaacgc tgatggcatt catcaccgcg tggcgtccgg
    51721 caaaatgttc ttctggcaaa tagcgacaat cggaacgcgg ataagtgatt aacttgtgtg
    51781 tttcgtacag cttctggcag atatcaagca cgttctgcgc gctcagacca aagcgttttg
    51841 ccgcttcaat ctgcaacgcc gaaagcgaaa acggcagcgg cgcggattct gattcccgtt
    51901 tatcgttata gctggtgaca atagccggtt gaccactaat gcggttaacc acatgctccg
    51961 ccagtggacg atgtaacaag cgcccttctt catcctggta cggttcacac gcttcgctcg
    52021 gttgccagat agcggtaaac cgctcatcgg caggtgtcac gatatgcgct ttgacttcaa
    52081 agaagtcttt cgccacgaag ttttcaatct cttcatcgcg gcgcaccacc agcccgagca
    52141 cgggtgtctg cacgcgtccc acggaaagta cgccctgata accggcattg cgaccgagaa
    52201 tggtatacgc acgggtcata ttgatgccgt acagccagtc ggcacgcgct cgcgccagcg
    52261 cagaaacgca caatggcaca aactcactgt tggaacgaag acggtcgatc gcccgctcaa
    52321 ccgcctgcgg gttcaggtcg tttatcaagc aacgctgcac ctgctggcgc ttttccggtg
    52381 ccagttgcag atagtccagc acttcatcca ccagcaattg cccttcacga tccgggtccc
    52441 cggcgtgaac gatttcgctg gcttcatgca ggaagcgttt gatgacgtta agttgtttgg
    52501 tcacggaggg tcggggctgt aattgccact tttccgggac aatcggcaaa tccgcaagat
    52561 tccagcgcgc atagcggctg tcgtaggcgt ctggctgcgc ctgctcaagc aggtgaccga
    52621 tacaccaggt caccacctga ccattaccgc actcgataaa gccatcgcct ttacggtgcg
    52681 gtttgggcag gacatcagca atggcgcgcg ccagactcgg tttttcggca ataaacaacc
    52741 gcattgaatt aacggatctc aaccatggca cgaccgccgc gcgctggcac cagttcgcca
    52801 atcgccgtca gttcaatgcc aaactcggcg gctgtagttt taacctcatt ttctgcttcc
    52861 ggcatgaccg ccagcagcaa accgccagaa gtttgcggat cgcacagcag atcgcgcact
    52921 tcacgcggca tttcacccat cagatgaccg tagctggcaa agttacgttc ggtgccgcca
    52981 ggcactgcgc ccaacttaat gtactcttca acccccggca attttgggat cgcgtcatag
    53041 tcaacgcgcg cctgcacacc tgcgccctga cacatttcgc tcaaatggcc cagcagacca
    53101 aaaccagtaa cgtcggtcat cgcttttacg ccttcgatgt tggcaaagga cgcacctgcg
    53161 atgttcatcc ggcacatcac ttccgtcgcc agtccctgat gttctggttt caacagtgat
    53221 tttttctcag ccgtggtaag aacgccgatc cccagcggtt tcgtcaggaa cagtttgcat
    53281 ccggcttgtg cggtactgtt tttcttcacc cgctcggtcg gtacgatccc cgttaccgcc
    53341 agaccaaaaa tcggctccgg cgcatcgatg gagtgacccc cagccagcgc aatacccgcc
    53401 tgacggcatg catagcgtcc accttcggtt acttcgcggg caatttctgg ggaaagtttg
    53461 ttaatcggcc agccgaggat cgcaatcgcc ataatcggtt tgccccccat cgcgaagata
    53521 tcgctgatgg cgttagtcgc cgcaatgcgg ccaaaatcga aaggattatc aacgatcggc
    53581 ataaagaagt cggtggtact gataacgctg gtgccattgc ccagatcgta caccgccgca
    53641 tcgtcgcggg tctcattacc cacaagcaaa ttcggatcaa caaacttcgc ctgctcactg
    53701 tgcaggatgg tttccaacac ttttggggaa attttacagc cgcaaccagc tccgtggctg
    53761 tattgggtca aacgaatcga gttctcgctc atggacatct cctgtcaatg caatccgggt
    53821 atggtaaccc tcattccgtg aagtgataag tgagagtgtc tgaattcctg cgcctttgct
    53881 cacaatccag acagtttcgc gacaattatc agaaataagt tacaaacggc gtcgggtccg
    53941 ggacgttaat cgacgtagat gctttcaact gcggcgtgcc gaggtagaga aaaccgacaa
    54001 ttttatcctg ctcacggcaa ccgaatgctt cacgcactac cggactttca gttaatgcgc
    54061 cactgcgcca gatgccgcca aatccttggg caacggctgc catttgcatc gccatgaccg
    54121 cgcatccggc agacatttcc tgttcccatc gcgggacttt atgattttct tcgcatttcg
    54181 ccaccaccgt gatgatgagc ggtgcgcgga acggcgcatt acgggctttg tcgatagctt
    54241 tgtcatcact accggcagca atcgccccct gttccagtac ggcgctgaaa cgctcgcgcc
    54301 cttccccttc aatcacaaaa aaatgccacg gttgcatgga cttatggtcc ggcgcacgca
    54361 tacccgcacg caggatgttt tgcagttgtt cacccgttgg cgcgggttca gccaggcggg
    54421 aggcgctacg gcgattgatc aatagttcga gtgcatccat ttgattaact cctgtcgtga
    54481 tatttattca caaaattaac acgagagtgg attttgttac agcacagtcc gcaattcctg
    54541 ctgacaagtg ccggttgggt cattacgata accacatcta ttgcgcctgt gacaggtgtg
    54601 accttaagtt gggagaatac atgcgaaccc tttggcgatt tattgccgga ttttttaaat
    54661 ggacgtggcg tctgctgaat ttcgtccgtg aaatggtact taacctgttc tttattttcc
    54721 tcgtactggt tggtgtgggg atctggatgc aggtcagtgg tggtgattcg aaagaaacgg
    54781 ccagtcgtgg cgcactgctg ctggacattt ctggtgtgat cgtcgataaa cccgacagtt
    54841 ctcagcggtt tagtaaatta agccgccagc tgcttggtgc cagttccgat cgtctgcagg
    54901 aaaactcact gtttgatatc gtcaacacca ttcgccaggc gaaggacgac cgcaatatca
    54961 ccggtatcgt gatggatctg aaaaacttcg caggcggcga ccagccgtct atgcagtaca
    55021 tcggcaaagc cctgaaagag tttcgtgaca gcgggaaacc ggtttatgcc gttggcgaga
    55081 actacagcca ggggcaatat tatctcgcca gtttcgccaa taaaatttgg ctgtcaccgc
    55141 aaggcgtggt tgatctgcac ggttttgcta ccaacggtct gtactacaaa tcgttgctgg
    55201 ataagctgaa agtttccacc catgtgttcc gcgtgggtac gtataaatct gccgttgaac
    55261 cgtttattcg tgatgatatg tcaccggcag cccgcgaagc tgacagccgc tggattggtg
    55321 agctgtggca aaactatctg aatactgttg ccgctaaccg gcagatccct gctcagcagg
    55381 tattccctgg cgcgcaaggg ttgcttgagg gtttaaccaa aaccggtggc gataccgcga
    55441 aatatgcact ggaaaacaag ctggtcgatg cactggcatc gagtgccgaa atcgaaaaag
    55501 ctctgaccaa agagttcggc tggagtaaga ctgataaaaa ttatcgcgcc atcagttatt
    55561 acgattacgc attgaaaacg ccggcagata ccggtgacag catcggtgtc gtcttcgcta
    55621 atggcgcaat tatggatggc gaggaaactc aggggaatgt tggcggtgat accactgcgg
    55681 cacaaatccg cgacgctcgc cttgacccga aagtgaaagc gattgtcctg cgtgttaata
    55741 gcccaggcgg cagcgttacc gcgtctgaag tgattcgcgc tgaactggca gcagcccggg
    55801 cagcgggtaa gcctgtggtt gtatcgatgg gcggcatggc ggcatctggt ggttactgga
    55861 tttccacgcc agctaattac attgtggcta accccagcac cctgaccggt tctatcggta
    55921 tcttcggcgt gatcaccacc gtagaaaata gtctggattc gattggtgtt catactgatg
    55981 gtgtctcaac ttcaccgctg gcggatgttt ctatcaccag ggcactgccg ccggaagcgc
    56041 agcagatgat gcaattaagc attgagaatg gctataaacg ctttatcacg ctggttgctg
    56101 atgcgcgtca ttcgacgccg gagcaaattg ataaaatcgc ccagggccac gtctggaccg
    56161 gtcaggatgc aaaagctaac gggctggtcg atagtctcgg ggatttcgat gatgcggttg
    56221 ccaaagcagc agagctggca aaagtgaaac agtggcatct ggaatactac gttgatgaac
    56281 cgaccttctt cgacaaagtg atggacaaca tgtctggttc tgtccgggca atgttgccag
    56341 atgcgttcca ggccatgtta cctgcaccgc ttgcctcggt agcctctacc gttaaaagtg
    56401 aaagcgacaa gctggccgcg tttaacgacc cacaaaaccg ttatgcgttt tgcctgacct
    56461 gcgccaacgt gcgttaagtc ttgtactgag tggccgacag atcgtcggcc acattatttt
    56521 ttacctcgac gaatcctctt cccgctgtct cgacccatat ttccttatcc gcatagtatc
    56581 aggtgcgctc ctcctgcctc acgtatatac ttttgctctt tcgatatcat tcatatcaat
    56641 atcatgcaaa agaaatcaat ttacgtcgcc tacacgggcg ggaccatcgg gatgcagcgt
    56701 tccgagcagg gttatattcc ggtgtcaggt catctacaac gccaactggc gctgatgccg
    56761 gaattccatc gcccggagat gccagatttc accattcatg aatatacgcc gttgatggat
    56821 tcttctgata tgacgccgga agactggcag catattgctg aagatattaa agcgcactat
    56881 gacgactatg atggttttgt cattctacac ggtaccgaca cgatggcgta taccgcctct
    56941 gcgctgtcgt tcatgctcga gaatctcggt aaaccggtca ttgtgacagg gtcacaaatc
    57001 ccgctggctg agttacgctc tgacggacaa attaatctgc tgaatgcgtt gtacgttgcg
    57061 gcgaattatc cgatcaacga agtaacgctc tttttcaata accgattgta tcgcggcaac
    57121 cgcactacca aagcccatgc cgatggtttt gatgcgtttg cctctccaaa ccttcctccg
    57181 ttactggaag ctggtatcca tattcgtcgt ttgaatacgc cacccgcccc gcacggtgaa
    57241 ggggaattaa tcgttcatcc aatcacgcca caaccaattg gcgtagtgac gatttatccg
    57301 gggatttctg ctgatgtcgt gcgcaatttt ctgcgccaac cggtgaaagc attgattctg
    57361 cgctcctatg gcgtgggtaa tgcgccacaa aacaaagcct tcctgcagga attacaagaa
    57421 gccagcgatc gcggtattgt ggtggttaac ctgacacaat gtatgtccgg taaagtgaac
    57481 atgggtggtt atgccaccgg taacgccctc gcccatgccg gcgtaattgg cggtgcagat
    57541 atgactgtag aagctacgct aaccaaactg cattacctgc tgagccagga actggatact
    57601 gaaaccattt gcaaggccat gagccaaaac ctgcgcggcg aactgacgcc ggatgattaa
    57661 ggagactgca atgccccctc gcgccctgtt actggtcgat ttacaaaatg atttctgtgc
    57721 tggtggcgcg ctcgccgtgc cggaaggtga cagtacggtg gatgtcgcta accgccttat
    57781 tgactggtgc cagtcgcgcg gtgaagcggt tatcgccagt caggactggc acccggcgaa
    57841 tcacggcagt tttgccagtc agcactgtgt agagccttat atgccaggtc aactcgacgg
    57901 tttgccacaa accttctggc cagatcactg tgtgcagaac agtgaaggcg cacaattaca
    57961 tccgttactg aaccaaaaag cgatcgcagc ggtgttccat aaaggcgaaa atcctttagt
    58021 tgacagttac agtgcctttt ttgataacgg ccgtcggcag aaaacctctc tcgatgactg
    58081 gttacgcgat catgaaatcg atgaattgat cgttatgggc ctggctactg actattgcgt
    58141 gaagtttacc gtgctggacg cgttacagtt aggttataaa gtaaacgtga ttaccgatgg
    58201 ttgtcgtggc gtgaatatcc agccccagga cagtgcgcac gcgtttatgg agatgtcagc
    58261 agctggggca acgctatata cgctggcaga ctgggaagag acgcaggggt aatattagtt
    58321 gaattcatct ctggcctaca tttcctcaat gacattgtag gccagataat acttgtcagt
    58381 gttgcattta acctacttgc agctaaaaca cgacgtccta acaagtatat ttgccctccc
    58441 ttaataacag gcttaaatat tagataactc attcacttaa acatagcaat aggctttgct
    58501 gagataccaa aatcttcttt taactgctgt ttgctcttca tgaccatctg accatttgtg
    58561 tcaattgtca tatgctgtgc ttcggtatta tggcgggctt gccacagcat caccagttgc
    58621 aggcaattct ctttttgttc ctcggtcaac gcaacgccat caggccattt ccccagttca
    58681 acggcggtcg acaaacgctg gtatacctca ggcgtcatgc tgttgataat gtcatcaaga
    58741 ttcataattt ttccgctcct gtggaataag ttgctgaatc gttttttcaa ccgttgattt
    58801 cttcgccgtt ttcgccatcg gtaaagcgta aagaggcaga gttaacacaa taacgttcgc
    58861 ccgttggctg cggcccgtca gggaagacat gccccagatg ggcatcacag ttaccgcaac
    58921 gaatttctat gcgctgcatt ccatgtgaca agtctttgat ataacgaatg gattcttcac
    58981 tcaccggttc gtagaaactg ggccaaccac agccggaatc atacttggtt tgggaatgaa
    59041 acagcggggc atcgcagatc aaacagtgat atacgccgtc acgcttgtta tgcagtaaac
    59101 gacccgtaaa tggcggctct gtcccatgat tctgcgtcac gtaaaactgc atctcggaca
    59161 aatttttttt cagttcttct gccgaaggtt tattagccat ttgctcacat ctcactttaa
    59221 tcgtgctcac attacgtgac tgattctaac aaaacattaa caccaactgg caaaattttg
    59281 tcctaaactt gatctcgacg aaatggctgc acctaaatag tgatgaaaat cacattttta
    59341 tcgtaattgc cctttaaaat tcggggcgcc gaccccatgt ggtctcaagc ccaaaggaag
    59401 agtgaggcga gtcagtcgcg taatgcttag gcacaggatt gatttgtcgc aatgattgac
    59461 acgattccgc ttgacgctgc gtaaggtttt tgtaatttta caggcaacct tttattcact
    59521 aacaaatagc tggtggaata tatgactatc aaagtaggta tcaacggttt tggccgtatc
    59581 ggtcgcattg ttttccgtgc tgctcagaaa cgttctgaca tcgagatcgt tgcaatcaac
    59641 gacctgttag acgctgatta catggcatac atgctgaaat atgactccac tcacggccgt
    59701 ttcgacggta ccgttgaagt gaaagacggt catctgatcg ttaacggtaa aaaaatccgt
    59761 gttaccgctg aacgtgatcc ggctaacctg aaatgggacg aagttggtgt tgacgttgtc
    59821 gctgaagcaa ctggtctgtt cctgactgac gaaactgctc gtaaacacat caccgctggt
    59881 gcgaagaaag tggttatgac tggtccgtct aaagacaaca ctccgatgtt cgttaaaggc
    59941 gctaacttcg acaaatatgc tggccaggac atcgtttcca acgcttcctg caccaccaac
    60001 tgcctggctc cgctggctaa agttatcaac gataacttcg gcatcatcga aggtctgatg
    60061 accaccgttc acgctactac cgctactcag aaaaccgttg atggcccgtc tcacaaagac
    60121 tggcgcggcg gccgcggcgc ttcccagaac atcatcccgt cctctaccgg tgctgctaaa
    60181 gctgtaggta aagtactgcc agaactgaat ggcaaactga ctggtatggc gttccgcgtt
    60241 ccgaccccga acgtatccgt agttgacctg accgttcgtc tggaaaaagc tgcaacttac
    60301 gagcagatca aagctgccgt taaagctgct gctgaaggcg aaatgaaagg cgttctgggc
    60361 tacaccgaag atgacgtagt atctaccgat ttcaacggcg aagtttgcac ttccgtgttc
    60421 gatgctaaag ctggtatcgc tctgaacgac aacttcgtga aactggtatc ctggtacgac
    60481 aacgaaaccg gttactccaa caaagttctg gacctgatcg ctcacatctc caaataagtt
    60541 gagatgacac tgtgatctaa aaagagcgac ttcggtcgct ctttttttta cctgataaaa
    60601 tgaagttaaa ggactgcgtc atgattaaga aaatttttgc ccttccggtc atcgaacaaa
    60661 tctcccctgt cctctcccgt cgtaaactgg atgaactgga cctcattgtg gtcgatcatc
    60721 cccaggtaaa agcctctttt gcattacagg gcgcacacct tctctcgtgg aaacctgcgg
    60781 gtgaagaaga agttctgtgg ttgagcaaca acacaccgtt caaaaatggc gtcgctattc
    60841 gcggtggcgt accggtttgc tggccgtggt ttggtccggc ggcacaacaa ggtctgcctg
    60901 cgcacggttt tgcccgcaac ctgccgtgga cgctgaaatc acatcgtgaa gatgctgatg
    60961 gcgtagcgct gacttttgaa ttgacgcaaa gcgaagagac gaaaaaattc tggccgcacg
    61021 actttacgct gttagcgcat ttccgcgtgg gtaaaacctg tgaaatcgat cttgaatcac
    61081 atggcgaatt tgaaaccacc tctgccctgc atacctactt taacgtgggt gatatcgcta
    61141 aggtaagcgt cagtgggctg ggcgatcgct tcattgataa agtaaatgac gcgaaagaag
    61201 atgtactgac cgacggtatt cagaccttcc ctgaccgtac cgatcgcgtg tatctgaatc
    61261 cgcaagattg cagcgtgatt aatgatgaag cgctgaatcg tattatcgcc gtaggccacc
    61321 agcatcatct gaacgttgtc ggctggaacc cgggaccggc gctttcagtt agcatgggcg
    61381 acatgccgga tgatggctac aaaacatttg tttgtgtaga aacggcttac gcttcagaaa
    61441 cgcaaaaagt gaccaaagag aaacctgcac atctggcgca atccattcgc gttgcgaaac
    61501 gttaatttgc gttaatgttg tgtgccgggt gcgatgcatc cggcacgtat caacatcaca
    61561 ccatatccag cgcagttttt ccttttggtg ccggatacgc tttatccagc atgattaatt
    61621 ccgctgacga aagttcgacc tcaagcacag ccgcattctg ttggacatgg gcaatcgtgg
    61681 ccgcttttgg aatcgccatc acaccctgat ggctgattac ccacgccaac aatacttgtg
    61741 ccgcgctgat attgtgagca tgtgcaattt cgttgactac cgcgtttttt aacagtccat
    61801 tgcgcaaccg cccggcctgg gctaatggac tgtaagccat taccggcatc tgctgttgct
    61861 ggcaccaggg gagtagatcg tactcaatcc ctcgtgaacc gagatggtaa agcacctgat
    61921 tagtggcaca ctgatttccc cccggcagct gccagagttc ctgcatatca gcataatcaa
    61981 ggttagaaac gccccagcgg cggatttttc cctgggcgat caatttttcc atcgctgcca
    62041 cagtctcttc aaaagcgaaa ctgccagacc agtgtaataa gtagagatcg agataatcag
    62101 tattgagacg gcgtaaactg gcttcgcatg catttatcgc tttttgcccg ccagcattcc
    62161 acggatagac tttagagacg agaaagacgt tatcgcgcag atcggttaat gcttccccaa
    62221 ccaccttttc ggcaccgcca tcggcataca tttcggcggt atcaatgagg gttaaaccga
    62281 gctcaatgcc cgcgcgtagt gcagcaactt ctgttttgcg ctgactggca tcttcgccca
    62341 tataccatgt tccctgccct atggctggca gtgagacatc gccactaaat tgaatcattt
    62401 tttgttgcat tgtttcctcc caggtattgc accaccgtaa tgcaaaacag ggcgtgacgc
    62461 cctgttttta tgcacaaaat gccctggaaa gatgcattat cagaatttgt aggtgatccc
    62521 ggtagaaatc aggccagtcc aggatttatc caccatcggg ctgtcagtaa cttcatcaga
    62581 cagacgggta tagcgcgcgg taccgtaaac actccagtcg ccgaggaagt tgtagctggc
    62641 gctcagctcc aggtaagggc tccagctgtc gttcgggtta tagccacgca gaccgctgcg
    62701 agcggactct ttgcgcgata cgccataata gtattcgttc tggttttcgc tgttccactg
    62761 cacaccaata cccggagtca cggtcaggcc accgttggtg taacgataca accaggccat
    62821 atcccagaca atgccgttgc tgttatccag ggtatcgcca gccagggtgg tacgcaggta
    62881 accgtactgg gtaaagtgag cataagacag accagccatc atggtgctct tacggtcatc
    62941 caggtgacgc atttggtgat cgccactgtc tttcgctttg aagtaaagcg gcgaccagta
    63001 agcggtaatt gaaagtttat ccgttgcgtc attccacagg tagtaaccac cacctaagcc
    63061 acggaaccag aagttatcgc cttcatagtt gattaccggt actgggtaaa catcggtatc
    63121 gtaatcttta tatgggtgct caacgacacc tacgcctgcg cccagggaaa atttaccttc
    63181 agcgtgcgct acgcctgcag acgttgcgat aagcactcca agtgccagaa gtttgagttt
    63241 ggtcacaatt aatcattcct taaacaaatg tttagcgggc gacaaagttt acccgtcaat
    63301 acatcgaaac ccaacctttt tacgttttca ttttttaaag taactgttta attttcctga
    63361 cgcggatgac accgcgctta cagccaaatg aatttagcgt tactggctac cctggtcttt
    63421 acattaatta tgcaaaattt atggatgagt tgttgatatg ccattgaaat taagaaagcc
    63481 gtgcaggcaa gttttccatt tgccatctac gcttaatttt gaaggtgtat caccgggcac
    63541 gttgttctca tcgtcgataa aatggcatga gagttgctgt gttttagcaa gagacgtcgt
    63601 tcagtttacc tcttccggga gcctctacta ttcatatgaa cggctcttaa cctgtgctaa
    63661 aaaacgaaag gacggcatac catgaatata ttcgatcact atcgccagcg atatgaagct
    63721 gccaaggacg aagagttcac actgcaggag tttcttacca cttgtcggca agatcgcagt
    63781 gcttatgcca acgcggctga gcggctattg atggctatcg gtgagcctgt catggtcgat
    63841 acagcccagg aacccagact ttctcgactc ttttctaacc gggtcattgc acgttatccg
    63901 gcgtttgaag agttttacgg catggaagac gcgattgaac agattgtctc ttatctgaaa
    63961 cacgcggctc aggggctgga agagaagaaa caaatcctgt atctgctggg gcctgtgggt
    64021 gggggtaaat catcgcttgc tgagcgactg aaatcattaa tgcagctcgt accgatttat
    64081 gtattgagcg ccaacggtga gcgtagcccg gtcaacgatc atccgttctg tcttttcaat
    64141 ccgcaggaag atgctcagat tctggaaaaa gagtatggca ttcctcgccg ttatctcggc
    64201 accatcatgt cgccatgggc ggcaaaacgc ctgcatgaat ttggtggcga tatcactaag
    64261 ttccgggtag tgaaggtctg gccgtcaatt ctgcaacaaa ttgctatcgc caaaacggaa
    64321 cccggtgatg agaacaacca ggacatctcc gcgctggttg ggaaagtcga tattcgtaaa
    64381 ctcgaacact acgcgcagaa tgacccggac gcctacggct attccggtgc gctgtgccgc
    64441 gccaaccaag ggatcatgga gttcgttgag atgtttaaag caccgataaa agtgctgcat
    64501 ccgctgttaa ccgccactca ggaaggtaac tacaacggga cggaaggtat ctccgccctg
    64561 ccgttcaacg ggattatcct cgcccactcg aacgaatccg aatgggtcac tttccgtaat
    64621 aacaaaaaca acgaagcctt tctcgaccgt gtttacatcg tgaaggtgcc gtattgcttg
    64681 cgcatttccg aagagatcaa aatctacgag aaattgctta atcacagtga attgactcac
    64741 gccccatgcg cccctggcac gctcgaaaca ctgtcacgtt tttccattct ttcgcgcctg
    64801 aaagagccag aaaactccag catttattca aagatgcggg tttatgatgg cgaaagtctg
    64861 aaagacaccg atcccaaagc caagtcgtat caggaatatc gtgactacgc cggtgtcgat
    64921 gaagggatga acggtctgtc gacgcgtttt gcgtttaaga tcctctcccg cgtgttcaac
    64981 ttcgatcatg tagaagtggc agcaaacccg gtccatctgt tctacgtcct ggaacagcag
    65041 atcgagcgcg agcagttccc acaagagcag gcagaacgct atctggagtt cctgaaaggt
    65101 tatctgatcc cgaaatatgc cgagtttatc ggcaaagaga tccagacggc ctaccttgaa
    65161 tcctattccg aatatgggca aaacattttc gaccgttatg ttacctacgc ggatttctgg
    65221 attcaggatc aggagtatcg cgatccggat accgggcagc tgtttgaccg cgagtctctt
    65281 aacgccgagc tggagaaaat cgagaaaccg gcggggatca gtaatccaaa agatttccgc
    65341 aacgagattg ttaacttcgt actgcgcgcc agagcgaata acagcggacg aaatccgaac
    65401 tggagcagct atgaaaaact gcgcacggtt atcgagaaga aaatgttctc caataccgag
    65461 gagctgttgc cggttatctc gtttaacgcc aaaacgtcaa ccgacgagca gaagaaacac
    65521 gacgactttg tcgaccgtat gatggaaaaa ggctacaccc gtaaacaggt gcgtttactg
    65581 tgcgaatggt atttgcgcgt acgtaaatcg tcttaacaac cctggcccgg tacacatgct
    65641 accgggccta caacgacagc gaaccgtggg ccagagaaat ggcaacacag gcgtagcata
    65701 cagttggcaa atgtagtacg gggggcatat gacctggttt attgaccggc gtctgaacgg
    65761 caaaaacaaa agcatggtga atcgccagcg ttttttacgc cgttataaag cgcaaattaa
    65821 acagtcgatc tccgaggcca ttaataagcg ttcggtgact gacgtcgaca gcggcgaatc
    65881 cgtatccatt cccacggaag atattagcga accgatgttt catcaggggc gtggcggtct
    65941 gcgccaccgc gtgcatccgg gcaatgacca tttcgtccag aacgaccgaa ttgaacgtcc
    66001 ccagggtggc ggcggaggtt ccggcagtgg acagggccag gccagccagg atggtgaagg
    66061 tcaggatgaa tttgtctttc agatttcgaa agatgagtat cttgatctgc tctttgaaga
    66121 tttggcttta ccgaatctga aacaaaacca acaacgccag ctgaccgaat ataaaacgca
    66181 tcgggcgggt tataccgcta acggcgttcc ggccaatatc agcgttgtac gttccttgca
    66241 gaactcactg gcgcgtcgca cagctatgac ggcgggcaag cgacgggaac ttcatgcgct
    66301 ggaagagaat ttggccatca tcagcaacag tgaacctgcg caactgctgg aagaggaacg
    66361 tctgcgcaaa gaaattgcag aattacgtgc caaaattgaa cgcgtccctt tcattgacac
    66421 cttcgattta cgttacaaga actacgagaa gcggcccgat ccctccagcc aggcagtgat
    66481 gttttgcctg atggacgttt ccggttcaat ggatcaatcc actaaagata tggctaagcg
    66541 tttttatatt ctgctgtatc tgttcctcag cagaacgtat aagaacgtgg aagtcgtata
    66601 catccgccat catacccagg cgaaagaagt cgatgaacat gagtttttct actcgcagga
    66661 aacaggcggc accattgttt ccagcgccct gaaactgatg gatgaggtag tgaaagagcg
    66721 ttataacccg gcacagtgga atatttacgc tgcacaagca tcggacggcg ataactgggc
    66781 cgatgactct ccgctttgcc atgaaatcct ggcgaaaaaa ttattacctg ttgttcgtta
    66841 ttacagctat atcgaaatta cccgtcgtgc acatcagaca ttgtggcgag aatatgagca
    66901 tctgcaatct actttcgaca actttgcgat gcagcacatc cgcgaccagg atgatattta
    66961 tccggtattc cgtgaactgt ttcataaaca aaatgcaaca gctaaagact aaaactatca
    67021 gccgggtcat tatcgcctgg ctgattttta gcttactgta aattatctca tttattacat
    67081 acattagctt acaatcgctt taaatatgac agcataacct ttacataatt tagttccaga
    67141 aaacaatcat tcggaaaaat gattcagtca acacgtattt ccatggggtt attctttaaa
    67201 tattttttat cgttaacgaa aattgatcct ggtcaaaact atatatctct gccatcaata
    67261 aaatccagca ctcacattgc tctccttttt atggtttcta tgggtacaca aaaattaaaa
    67321 gctcaaagct tttttatttt cagtttattg ctgacgttaa ttttattttg catcaccaca
    67381 ttatataacg aaaacacgaa tgtaaaactc atcccacaga tgaattatct gatggtcgtt
    67441 gtggctttgt ttttccttaa cgccatcatt tttcttttca tgttaatgaa atatttcact
    67501 aacaaacaaa ttctaccaac actcatttta agtcttgcat ttttaagtgg ccttatctat
    67561 ttagttgaaa ctattgttgt tatccataaa cctatcagcg acagtacact gatccagaca
    67621 aagtcgaatg atgtttctat tttctatatt ttccgccaac tcagttttat ttgtttaacc
    67681 tcgctggcgc tcttttgtta tggtaaagac aacatccttg acaacaataa gaaaaaaact
    67741 ggcattctgt tgctggcgct gattcctttt ttagtttttc cccttctggc acacaatctg
    67801 agcagttata acgctgacta ttctttgtat gtcgtcgatt actgtccgga caaccatact
    67861 gcgacctggg gaatcaacta tacaaaaata ttggtttgtc tgtgggcatt tttactgttc
    67921 tttattatca tgcgtacacg attagccagc gaactatggc cgttaatagc attattatgt
    67981 ctggcatcgc tatgctgcaa cttacttcta ctgactctgg atgagtataa ttacaccatc
    68041 tggtatatca gtcgcgggat tgaagtttcc agtaaactgt ttgttgtgtc ttttctgatt
    68101 tataacattt ttcaggaact gcaactctcc agcaaactgg cagttcatga tgtgctgacc
    68161 aatatttata atcggcgcta ctttttcaac agcgtagagt cattattgtc gcgacctgtt
    68221 gttaaggact tttgtgtcat gctggttgat attaatcagt tcaaacgcat caatgcccaa
    68281 tggggacatc gtgtgggtga taaagtgctg gtttcaattg tcgatattat ccagcaaagc
    68341 atccgccccg atgatatttt agcgcgactg gagggtgagg tgtttggctt gctatttacc
    68401 gaactcaata gtgcccaggc aaaaatcatt gcggaacgta tgcgtaaaaa tgtcgaactc
    68461 ctgaccggct ttagtaacag atatgatgtt cctgaacaaa tgaccatcag tattggcacg
    68521 gttttttcaa cgggtgacac gcgtaatatc tcgcttgtca tgacggaagc agataaagcc
    68581 ttacgcgaag cgaaaagcga ggggggcaac aaagtgatta ttcatcatat ttaagtgcaa
    68641 aaatattcag agccatgctt tttgcgtggc ttttgcatac aatttattac tattacccct
    68701 aaatttcccc tccccagcgg cgcagagatg agtataatta gcgcccctgt gccaggccgc
    68761 aatcgaactt tatctggttt tctcgtttca ctaaccgaag gagtgccatt tatcatgaaa
    68821 ttgcaccata gaatgctccg gcattttatc gccgcaagtg tcattgtgct gacatcttcc
    68881 ttccttattt ttgaacttgt cgccagcgac agagcaatga gcgcctatct gcgctatatt
    68941 gtgcagaaag cagactcctc ctttctttat gataagtatc agaatcagag tattgccgcg
    69001 catgtgatgc gcgctctcgc tgctgagcag tcggaagtgt cgccagaaaa gcggcgcgcc
    69061 atctgcgagg cttttgagtc tgccaataat acccatggct taaacctgac tgcccataaa
    69121 tacccgggct tacgcggcac actacaaacc gcatccactg actgcgacac aattgtggaa
    69181 gctgcagcgc tattacccgc ttttgatcag gcagtggaag gcaaccgcca ccaggatgat
    69241 tacggttcag gtcttgggat ggccgaagaa aaatttcact attatctcga tctcaatgac
    69301 cgctatgtct atttttatga gccggttaat gttgaatact ttgcgatgaa taactggtcc
    69361 ttcctgcagt caggaagtat tggcatcgat cgcaaagata ttgaaaaggt atttaccggg
    69421 cgtaccgtat tgtcgagcat ttaccaggat cagcgtacta aacagaacgt gatgagtttg
    69481 ctgacgccgg tatatgtcgc agggcagcta aaagggattg tgctgctgga tattaacaaa
    69541 aacaatctgc ggaatatctt ttatactcat gaccgccctc tcctctggcg ttttctcaat
    69601 gtcacgctaa ccgataccga ttcggggcgc gacattatca tcaaccagag cgaagataat
    69661 ctgttccagt atgtcagtta cgtccatgac ttaccgggcg gcattcgtgt ctcgttatcc
    69721 attgatattc tttactttat cacgtcttcg tggaaaagcg ttctgttctg gattttgacg
    69781 gcgttaattt tgctgaatat ggtccggatg cacttccgtt tataccaaaa tgtgtcgcga
    69841 gaaaatatta gtgatgcaat gactggactg tataatcgca aaattttaac ccctgaactg
    69901 gaacagcggt tgcagaaact ggtgcaatcc ggttcttcgg tgatgtttat tgctattgac
    69961 atggacaagt taaagcaaat aaatgacacc ctcggtcatc aggaggggga tttagcgatt
    70021 acgttattag ctcaggcgat taaacagtcg attcgtaaaa gtgattatgc catccgactc
    70081 ggtggcgatg aattctgcat cattcttgtc gattcgacgc cgcaaattgc agcacaactg
    70141 cctgaacgta tcgaaaaacg tctgcaacat atcgcgccgc agaaagagat cggcttctct
    70201 tccggtattt atgcgatgaa agaaaacgat acgttacatg atgcgtataa agcttccgat
    70261 gagcgtttat atgtcaataa gcagaacaaa aacagccgtt catgataacc ttctgtggtt
    70321 gtttgcttgt aatctcagga gcatgaaatg actgaaatgg ctaaaggaag cgtgacgcat
    70381 caacggttaa tcgctttatt atcacaagaa ggtgctaact tccgcgtcgt tacccatgaa
    70441 gcggtaggta aatgtgaagc ggtgtcagaa attcgtggca ccgctttagg ccagggagct
    70501 aaggcactgg tatgtaaggt caaaggcaat ggcgtaaatc aacatgttct ggcgatcctc
    70561 gctgccgatc aacaggccga tctgagccaa ctcgccagcc atataggcgg attacgcgct
    70621 tcgttggcca gcccggcgga agtcgatgaa ctcacaggct gtgtcttcgg cgcgatcccc
    70681 cctttcagct tccatccaaa actcaaactg gttgccgacc ctctactctt cgaacgattt
    70741 gatgaaatcg ccttcaatgc aggcatgctg gataaatccg ttattttgaa aaccgcggat
    70801 tatttgcgca ttgcgcaacc agaactggtc aatttccgcc gcactgcgta actagcctgt
    70861 ccgttcaata agcagaacgg acaaaaccag cacaaccgca atggcaaaaa acgatgacga
    70921 gataatcagt gtctcgacga acatttgatc gttcatagta tgcccccggg agatagctgt
    70981 tttcacgtta ttgttagcgt gcaccaatgg cagtttgatg acagttcgcc tgatttttta
    71041 tgcaaaaaac gtaaagattt tctacttcct tcctgcagca agcgtaaagt aagcaggctt
    71101 attatttttt ggcaaggaaa ccacgatgtt tgatgtcact ttgctgatcc tgctcgggtt
    71161 agctgcgctg ggctttatca gtcataacac cactgtcgcc gtttcaattc tggtgttgat
    71221 cattgtccgc gtcacaccgt taagcacctt tttcccgtgg attgaaaaac aggggctaag
    71281 tatcgggata atcattctga cgattggcgt tatggccccc atcgccagcg ggacgctacc
    71341 gccctcaacc ctgattcact cgtttctgaa ctggaaatcg ctggtggcaa ttgcagtagg
    71401 cgttattgtc tcctggctgg gtgggcgcgg cgtgacgtta atgggcagcc agccgcaact
    71461 ggttgctggg ctgctggtgg gcactgtttt gggcgtggcg ctgtttcgcg gcgtaccggt
    71521 tggcccgctt attgccgcgg gtctggtttc gctgattgtg gggaaacagt agttaatccc
    71581 gcaatatatc ggcctggcgt ttgccccagg cctttcttaa acatagtaat aaaggccgtt
    71641 gttgaatcat accccagcgt atgagcaact ttctgtacag tatcgccttt cactaatccc
    71701 tgaagcgcca taatcagctg taactgctgt cgccactggc gaaaactcaa ccccgtctct
    71761 tttactatca gtcgggcaat attgcgttca ctcatcgcaa aaaagcaagc ccattgcccc
    71821 aatgaccccc actcgacggg ctctttcgcc atcatctcca ccatcgcgcg gattttagga
    71881 tgagaagaaa cgggtaggtg cagctgttgt tgtggctgct gagggagttc atcaaacagg
    71941 acctgaatta atctgcgggt catcggctca gcacgctgag tcgtcgtcct gtttgccaga
    72001 gttaaaatca attcccggca taagggcgat attttcaatg tgcaacaggt tgtcggcatt
    72061 atcactgcgc tgggttcgat aaacagaaaa cagagttcag cgttagctgt cacttgattg
    72121 ctatgttcca cccctcccgg tatccaaacc gcatattgcg gcggcaccat ccacaaagca
    72181 ttttccaccg tacaggtaat tgcaccatgt agcgccagta tcagctgtcc tttgcggtgc
    72241 tgatgtacag gactggttaa ctcatccgtt ccggcgtgaa tacaaaatgc gaccgcggct
    72301 tcatggtgtc ggtcgggttc atagccattg agattcaacc tgtgcatcat tttgtccgaa
    72361 tttagcgata atttgtcatt ttagcttgat tcaacataac aataaaaacg gtaaggtaca
    72421 gcctcgtttg taacaatgag aagcatatga cctgttcaac ttcattaagc ggcaaaaaca
    72481 ggattgtcct tatcgctggc attctgatga ttgccacaac attacgcgtc acctttaccg
    72541 gcgcagcgcc gttactggat acgattcgtt ccgcttactc gctgacgaca gcgcaaaccg
    72601 gcttattaac caccctgcca ttattggcct ttgcgctaat ctcacctttg gctgccccgg
    72661 tggcgcgacg ttttggtatg gaacgtagcc tgtttgccgc gttacttttg atctgtgcag
    72721 gtatcgcaat tcgttctctc ccttcgcctt acttattatt tggcggtaca gcggtcattg
    72781 gcggtgggat tgcattaggc aatgtcttac tgccaggatt aattaaacgc gatttccctc
    72841 attccgtcgc cagacttacc ggcgcatatt ccctgacaat gggagctgca gcggcactgg
    72901 gatcggctat ggtcgtgccg ctggctttga acggttttgg ctggcaaggc gcgttgttca
    72961 tgctgatgtg ttttcctctg ctggctcttt ttttatggct gccacagtgg cgaagccaac
    73021 aacatgcaaa tttgagtacc tcgcgcgcct tacatactcg gggtatctgg cgttcgccgc
    73081 ttgcctggca ggtcacattg tttcttggga tcaactcact ggtctattac gtgattattg
    73141 gctggcttcc ggcgatcctc atcagtcgcg gctatagcga agcacaggcg ggttcactgc
    73201 atggtttgct gcaactagcc acagcagctc ccggtttgct gatccctctt ttcttacatc
    73261 atgtgaaaga tcagcgtggt attgcagcgt tcgttgcctt gatgtgcgca gtgggcgctg
    73321 ttgggctctg ctttatgcca gcgcacgcga tcacctggac tctgcttttc ggttttggtt
    73381 ccggcgcaac aatgatactg gggttgacgt tcattggtct tcgggcaagt tctgcgcatc
    73441 aggcggcggc actctcgggg atggcacaat ccgtcgggta tttgctggca gcctgtgggc
    73501 cgccgctgat gggtaaaata cacgatgcta acggtgactg gtccgtacca ctgatgggtg
    73561 ttgccatact ttcactactg atggcgattt tcggactttg cgccgggaga gacaaagaaa
    73621 ttcgctaata tccggtgcta tagtgacgtg acaaatcatg cgtgaaaggg agaacaaaca
    73681 cgatgaatat tcagtgcaaa cgcgtttatg atccggctga acagagcgat ggttatcgcg
    73741 tactggtcga ccgcctctgg ccgcgcggta tcaaaaaaac cgatttagcc cttgatgagt
    73801 gggataaaga aatcacgccg tcaacggaac tgcgcaaagc ctttcacggc gaagtcgtcg
    73861 attttgcaac ctttcgcgag caatatcttg cagaactggc gcaacacgag caagaaggaa
    73921 agcggctggc ggacatcgcc aaaaaacagc ccctgaccct gctctacgca gcaaaaaaca
    73981 ccacgcagaa ccatgcgctg gtgctggccg actggctacg tagcttgtga ttttagtaca
    74041 gcatccggcg gttatttttc accagccgga tggtaccgtc gccacaatgc ccattcatca
    74101 atcgtttcac cgcccggtaa tttgcaattg ttgctgaccc cttgcgctgt ctgcactgga
    74161 atgagcgtcc cgcccttctg ctggcaatag accgacgccg gatttgccat accaatctgc
    74221 ggcggtttag gtgcttctgg ctgagaaggg gttgaacaac cagccaggac cagcaagcaa
    74281 ggcagaacaa aactgataat tttcatttat tgatctcaca tatttatcca gacttagagt
    74341 atcgcggtat cgttttgttt tgcagcacta tttttattac attcactcaa atcatattac
    74401 gccttgtttc atctttgttg atgatgtttt atcatgcctg caaagattaa ataatcagca
    74461 tttacccgcc gtatcctgga gttgtttcgt gtcagatcag attatcgccc gcgtctcgca
    74521 atcccttgcc aaagaacagt cactggaaag tctggtccga cagcttctgg agatgctgga
    74581 aatggtcact gatatggaat caacctacct gaccaaagtg gatgtcgaag cgcgcctgca
    74641 gcatattatg tttgcccgta acagccagaa aatgcacatc ccggagaatt ttaccgtctc
    74701 gtgggattac tcgttatgca aacgcgccat tgatgaaaat tgctttttca gcgatgaagt
    74761 ccctgaccgt tggggcgact gtattgcggc acgcaatctt ggcatcacca catttctgag
    74821 cacgccaatt cacttaccgg atggatcatt ctatggcacg ctttgcgccg ccagcagtga
    74881 gaagcgccag tggagtgaac gcgcggaaca ggttttacag ttattcgctg gactgattgc
    74941 acaatatatt caaaaagagg cgctggttga acagctgcgc gaagccaatg ctgcgctgat
    75001 tgcgcaatcg tataccgact cgttaaccgg gctaccgaat cggcgggcga tttttgaaaa
    75061 tctgacgacg ctgttttctc tcgcccggca tcttaaccat aagataatga tcgcgtttat
    75121 cgatctggat aacttcaaat taatcaatga ccgttttggt cataatagtg gcgatctgtt
    75181 tctcattcag gttggcgagc gccttaatac gctccagcaa aatggcgaag ttattggtcg
    75241 tctcggcggt gatgagtttt tggttgtttc actaaacaac gagaatgcgg atatttcgtc
    75301 gctgcgagaa cgtattcaac agcaaatacg tggagaatat cacttagatg atgttgattt
    75361 gtattatccc ggtgccagtc ttggcatagt agaagtcgat cctgaaacaa ccgatgcaga
    75421 cagtgccctg catgctgccg atattgcgat gtatcaggag aaaaaacaca aacagaaaac
    75481 accttttgtc gcgcatccag cgctacattc ctgaggcgta ttcacatcct tttgattggt
    75541 gataacatgc gaatcggtat tatttttccg gttgtaatct ttattacagc ggtcgtattt
    75601 ttagcatggt tttttattgg cggctatgct gccccgggag cataaagatg aaaaaaacaa
    75661 cgattattat gatgggtgtg gcgattattg tcgttctcgg cactgagctg ggatggtggt
    75721 aacgtcacct ctaaaaaata gcaaaggctg cctgtgtgca gcctttgtgc aatttaagcg
    75781 ttaactttta atcttcctgt agataaatag cacgacaatc gcaccaataa cggcaaccac
    75841 gaagctgcca aaattgaagc catcgacttt accaaagcca aacagtgtgc tgatccaccc
    75901 gccgactacg gcaccgacta tccccagcag aatagtcata aagaatccac caccatcttt
    75961 acctggcatg atccacttcg ccagaatacc ggcaataagc ccaaaaataa tccatgacag
    76021 aatgcccatt gtttcctcac ttatctgttt tgcattagcg ggttagtcgc tgataaaaag
    76081 catagcacaa catcgggagg gcaagatttg tgacgagcat cacggaggat ttttttgcgg
    76141 atggcacaga aattgcgcca tcaacgatca gtgataatta ccaaccacaa acatcatgtt
    76201 cgttttccgt gtcttgacat cctccacgcc ctgaatgacg aggatccctg ctacgttcag
    76261 gctgtcgcct gaatcatttc ggtgggttcc tgcttcaacg agcggcctga ctgcaccatc
    76321 tctccacagg caagaacggc gtgccccgcc gctaaaatgt tacgagcgcc gtttacatcg
    76381 gcgttcgctg tatatccaca tacctggcat ctgaattgac tttgtgacag gcgattttct
    76441 ttcgctgtat gaccacagca cgcgcaacgc tggcttgtgt acgctggcgg aacagcaagc
    76501 acctgaccgc cacgccagag ctgcttgtac tcaagctggc ggcgcatttc ataccagccc
    76561 tgatccagta tcgaacggtt taaacctgat tttgcccgga cattgcgccc cggctggctg
    76621 accgtacccg ctgctgactt tgacatgttg ctgaccttca aatcctcaat gactatcatt
    76681 gcgtggtttt tgctgacggt cgttgtgact ttgtgaaggt agtccctgcg gatatttgcg
    76741 atacgggaat gcagtcgctg tattttgcgt ttctgcttct gccagttgtt gctgaatttg
    76801 accttgcggc ttaactgtcg ctgaagtctc gcc
//
LOCUS       DAZUDJ010000013        76768 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.013, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000013 DAZUDJ010000000
VERSION     DAZUDJ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 76768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76768
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.013"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..283)
                     /locus_tag="ACHY1N_001297"
     CDS             complement(<1..283)
                     /locus_tag="ACHY1N_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415949.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4043634.1"
                     /translation="MKRLQAFKFQLRPGDQQECEMRRFAGACRFVFNRALALQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDLERAYKNFF"
     gene            291..722
                     /gene="tnpA"
                     /locus_tag="ACHY1N_001298"
     CDS             291..722
                     /gene="tnpA"
                     /locus_tag="ACHY1N_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFS4043635.1"
                     /translation="MILWSVKKETDIRRGRHCVFLMHVHLVFVTRYRRQIFDHDATEK
                     LRAYFSNVCADFEAELVEMDGEPDHVHLLINYPPKLAISSLVNSLKGVSGRLLRRDRP
                     DIAVRYYYKGVLWSPGYFASSCGGAPISVIRQYIEQQQTPG"
     gene            complement(738..926)
                     /locus_tag="ACHY1N_001299"
     CDS             complement(738..926)
                     /locus_tag="ACHY1N_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001569941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1869 domain-containing protein"
                     /protein_id="HFS4043636.1"
                     /translation="MGKATYTVTVTNNSNGVSVDYETETPMTLLVPEVAAEVIKDLVN
                     TVRSYPVRRKTPSFRAGI"
     gene            complement(930..1289)
                     /gene="yeaR"
                     /locus_tag="ACHY1N_001300"
     CDS             complement(930..1289)
                     /gene="yeaR"
                     /locus_tag="ACHY1N_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein YeaR"
                     /protein_id="HFS4043637.1"
                     /translation="MLQIPQNYIHTRSTPFWNKQTAPAGIFERHLDKGTRPGVYPRLS
                     VMHGAVKYLGYADEHSAEPDQVILIEAGQFAVFPPEKWHNIEAMTDDTYFNIDFFVAP
                     EVLMEGAQQRKVIHNGK"
     gene            complement(1460..2098)
                     /gene="leuE"
                     /locus_tag="ACHY1N_001301"
     CDS             complement(1460..2098)
                     /gene="leuE"
                     /locus_tag="ACHY1N_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HFS4043638.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGY
                     LAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIIRYLGAFYLLYLGSKILYATLKGK
                     NNEAKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTL
                     ELVSFCYLSFLIISGAFVTQYIRTKKKLTKVGNSLIGLMFVGFAARLATLQS"
     gene            complement(2225..3148)
                     /gene="dmlR"
                     /locus_tag="ACHY1N_001302"
     CDS             complement(2225..3148)
                     /gene="dmlR"
                     /locus_tag="ACHY1N_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310535.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DmlR"
                     /protein_id="HFS4043639.1"
                     /translation="MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLE
                     QTLNVVLLHRTTRRVTITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISS
                     FGFGRQVVAPALSALAKAYPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARK
                     LATNYRILCASPEFIAQHGAPKHLTDLSALPCLVIKERDHPFGVWQLRNKEGHHAIKV
                     TGPLSSNHGEIVHQWCLDGQGIALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVS
                     RLATSAKVRITVEFLRQYFAEHYQNFSLEHA"
     gene            3251..4336
                     /gene="dmlA"
                     /locus_tag="ACHY1N_001303"
     CDS             3251..4336
                     /gene="dmlA"
                     /locus_tag="ACHY1N_001303"
                     /EC_number="1.1.1.83"
                     /EC_number="1.1.1.85"
                     /EC_number="1.1.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional
                     D-malate/3-isopropylmalate/tartarate dehydrogenase"
                     /protein_id="HFS4043640.1"
                     /translation="MMKTMRIAAIPGDGIGKEVLPEGIRVLQAAAERWGFDLSFEQME
                     WASCEYYSHHGKMMPDDWHEQLSRFDAIYFGAVGWPDTVPDHISLWGSLLKFRREFDQ
                     YVNLRPVRLFPGVPCPLAGKQPGDIDFYVVRENTEGEYSSLGGRVNEGTEHEVVIQES
                     VFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEAMAENYPEIRW
                     DKQHIDILCARFVMQPERFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERTFP
                     SLFEPVHGSAPDIYGKNIANPIATIWAGAMMLDFLGNGDERFQQAHNGILAAIEEVIA
                     HGPKTPDMKGNATTPQVADAICKIILR"
     gene            4587..6197
                     /gene="yeaV"
                     /locus_tag="ACHY1N_001304"
     CDS             4587..6197
                     /gene="yeaV"
                     /locus_tag="ACHY1N_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310537.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter YeaV"
                     /protein_id="HFS4043641.1"
                     /translation="MMSNVKKKDVPLISISLVAILFIAAALSLFPQQSADAANAIYTF
                     VTRTLGSAVQVLVLLAMGLVIYLATSKYGNIRLGEGKPEYSTLSWLFMFICAGLGSST
                     LYWGVAEWAYYYQTPGLNIAPRSQQALEFSVPYSFFHWGISAWATYTLASLIMAYHFH
                     VRKNKGLSLSGIIAAITGVRPQGPWGKLVDLMFLIATVGALTISLVVTAATFTRGLSA
                     LTGLPDNFTVQAFVILLSGGIFCLSSWIGINNGLQRLSKMVGWGAFLLPLLVLIVGPT
                     EFITNSIINAIGLTTQNFLQMSLFTDPLGDGSFTRNWTVFYWLWWISYTPGVAMFLTR
                     VSRGRKIKEVIWGLILGSTVGCWFFFGVMESYAIHQFINGVINVPQVLETLGGETAVQ
                     QVLMSLPAGKLFLAAYLGVMIIFLASHMDAVAYTMAATSTRNLQEGDDPDRGLRLFWC
                     VVITLIPLSILFTGASLETMKTTVVLTALPFLVILLVKVGGFIRWLKQDYADIPAHQV
                     EHYLPQTPVEALEKTPVLPAGTVFKGDN"
     gene            6229..7353
                     /gene="yeaW"
                     /locus_tag="ACHY1N_001305"
     CDS             6229..7353
                     /gene="yeaW"
                     /locus_tag="ACHY1N_001305"
                     /EC_number="1.14.13.239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase, oxygenase subunit YeaW"
                     /protein_id="HFS4043642.1"
                     /translation="MSNLSPDFVLPENYCANPQEAWTIPARFYTDQNAFEHEKENVFA
                     KSWICVAHSSELANANDYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGK
                     AKNVITCPYHAWAFKLDGNLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPN
                     ATSVEDQLPGLGAKVLEACPEVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPG
                     FSDSVQVDRYWHTMHGNWTLQYGFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPI
                     KGMMTVIYEFPVDSETTLQNYDIYFTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQK
                     GLKSRGYRGQGRIMADSSGSGISEHGIAHFHNLLAQVFKD"
     gene            7409..8374
                     /gene="yeaX"
                     /locus_tag="ACHY1N_001306"
     CDS             7409..8374
                     /gene="yeaX"
                     /locus_tag="ACHY1N_001306"
                     /EC_number="1.14.13.239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase reductase subunit YeaX"
                     /protein_id="HFS4043643.1"
                     /translation="MSDYQMFEVQVSQVEPLTEQVKRFTLVATDGKPLPAFTGGSHII
                     VQMSDGDNQYSNAYSLLSSPHDTSCYQIAVRLEENSRGGSRFLHQQVKVGDRLTISTP
                     NNLFALIPSARKHLFIAGGIGITPFLSHMAELQHSDVDWQLHYCSRNPESCAFRDELV
                     QHPQAEKVHLHHSSTGTRLELARLLADIEPGTHVYTCGPEALNEAVRSEAARLDIVAD
                     TLHFEQFAIEDKTGDAFTLVLARSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCG
                     TCETAILEGEADHRDQYFSDEERASQQSMLICCSRAKGKRLVLDL"
     gene            complement(8428..9543)
                     /gene="rnd"
                     /locus_tag="ACHY1N_001307"
     CDS             complement(8428..9543)
                     /gene="rnd"
                     /locus_tag="ACHY1N_001307"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310540.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0033890 - ribonuclease D activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HFS4043644.1"
                     /translation="MITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFD
                     GEHLALIDPLGITDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQIL
                     AAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITA
                     KLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLAD
                     WRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVE
                     KAQTLPEEALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLL
                     NWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ"
     gene            complement(9625..11310)
                     /gene="fadD"
                     /locus_tag="ACHY1N_001308"
     CDS             complement(9625..11310)
                     /gene="fadD"
                     /locus_tag="ACHY1N_001308"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HFS4043645.1"
                     /translation="MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLV
                     DDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRI
                     VDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSL
                     TEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA"
     gene            complement(11515..12096)
                     /gene="yeaY"
                     /locus_tag="ACHY1N_001309"
     CDS             complement(11515..12096)
                     /gene="yeaY"
                     /locus_tag="ACHY1N_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein YeaY"
                     /protein_id="HFS4043646.1"
                     /translation="MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRV
                     MSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPTLGEPSRGRIYADVN
                     GFLDPVDFRGQLVTVVGPITGAVDGKIGNTPYKFMVMQVTGYKRWHLTQQVIMPPQPI
                     DPWFYGGRGWPYGYGGWGWYNPGPARVQTVVTE"
     gene            complement(12136..12831)
                     /gene="tsaB"
                     /locus_tag="ACHY1N_001310"
     CDS             complement(12136..12831)
                     /gene="tsaB"
                     /locus_tag="ACHY1N_001310"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFS4043647.1"
                     /translation="MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQD
                     ILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGA
                     WRKNGATRVLAAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPELVHERMQQLSGEW
                     VTVGTGWQAWPDLGKESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYL
                     RNNVAWKKLPGKE"
     gene            complement(12889..14799)
                     /gene="yoaA"
                     /locus_tag="ACHY1N_001311"
     CDS             complement(12889..14799)
                     /gene="yoaA"
                     /locus_tag="ACHY1N_001311"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFS4043648.1"
                     /translation="MTDDFAPDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVE
                     AGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLHSRDLPTVSKALKYTGNVALLKG
                     RSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTVDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPE
                     ADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKPGSW
                     IFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVPRNLPQTNQPGSAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSSR"
     gene            14931..15275
                     /gene="yoaB"
                     /locus_tag="ACHY1N_001312"
     CDS             14931..15275
                     /gene="yoaB"
                     /locus_tag="ACHY1N_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416323.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFS4043649.1"
                     /translation="MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
     gene            15697..15996
                     /gene="yoaC"
                     /locus_tag="ACHY1N_001313"
     CDS             15697..15996
                     /gene="yoaC"
                     /locus_tag="ACHY1N_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416324.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1889 family protein"
                     /protein_id="HFS4043650.1"
                     /translation="MPAVIDKALDFIGAMDVSAPTPSSMNESTAKGIFKYLKELGVPA
                     SAADITARADQEGWNPGFTEKMVGWAKKMETGERSVIKNPEYFSTYMQEELKALV"
     gene            complement(16116..16295)
                     /gene="yoaH"
                     /locus_tag="ACHY1N_001314"
     CDS             complement(16116..16295)
                     /gene="yoaH"
                     /locus_tag="ACHY1N_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HFS4043651.1"
                     /translation="MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRAN
                     HSGERIVARFEDEDE"
     gene            16369..17730
                     /gene="pabB"
                     /locus_tag="ACHY1N_001315"
     CDS             16369..17730
                     /gene="pabB"
                     /locus_tag="ACHY1N_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HFS4043652.1"
                     /translation="MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYS
                     RFDIVVADPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPF
                     QGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV
                     NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRF
                     HATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGT
                     LPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPF
                     PAVHHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCG
                     SIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQ
                     LEK"
     gene            17734..18312
                     /gene="nudL"
                     /locus_tag="ACHY1N_001316"
     CDS             17734..18312
                     /gene="nudL"
                     /locus_tag="ACHY1N_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0010945 - coenzyme A diphosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HFS4043653.1"
                     /translation="MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQP
                     GLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLP
                     PVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDS
                     HRVWLSWYEQYFVWGMTAGIIRELALQIGVKP"
     gene            18496..19860
                     /gene="sdaA"
                     /locus_tag="ACHY1N_001317"
     CDS             18496..19860
                     /gene="sdaA"
                     /locus_tag="ACHY1N_001317"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HFS4043654.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVEERERLLLAQGR
                     HEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQD
                     AANEVSVPYPLKSATELLAYCNETGYSLSGLAMQNELALHSKKEIDEYFAHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            19991..21589
                     /gene="pdeD"
                     /locus_tag="ACHY1N_001318"
     CDS             19991..21589
                     /gene="pdeD"
                     /locus_tag="ACHY1N_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFS4043655.1"
                     /translation="MQKAQRIIKTYRRNRMIVCTICALVTLASTLSVRFISQRNLNQQ
                     RVVQFANHAVEELDKVLLPLQAGSEVLLPLIGLPCSVAHLPLRKQAAKLQTVRSIGLV
                     QDGTLYCSSIFGYRNVPVVDILAELPAPQPLLRLTIDRALIKGSPVLIQWTPAAGSSN
                     AGVMEMINIDLLTAMLLEPQLPQISSASLTVDKRHLLYGNGLVDSLPQPEDNENYQVS
                     SQRFPFTINVNGPGATALAWHYLPTQLPLAVLLSLLVGYIAWLATAYRMSFSREINLG
                     LAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGWISPDVFIPIAEEHHLIVPLTR
                     YVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITE
                     RDALLDVDYRIARELHRKNVKLAIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSD
                     AVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRRHGVHILQGYLYAQPMPLRDFP
                     KWLAGSQPPPARHNGHITPIMPLR"
     gene            complement(21593..23149)
                     /gene="yoaE"
                     /locus_tag="ACHY1N_001319"
     CDS             complement(21593..23149)
                     /gene="yoaE"
                     /locus_tag="ACHY1N_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HFS4043656.1"
                     /translation="MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMDFSFSGRDLIMLFGGIFLLFKAT
                     TELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIIIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQANVQHDADNPMPMPI
                     PEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEIREQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQ
                     QALDVEHLADDDDIATVAGLVISANGHIPRVGDVIDVGPLHITIIEANDYRVDLVRIV
                     KEQPAHDEDE"
     gene            complement(23137..23295)
                     /gene="yoaL"
                     /locus_tag="ACHY1N_001320"
     CDS             complement(23137..23295)
                     /gene="yoaL"
                     /locus_tag="ACHY1N_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518795.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YoaL"
                     /protein_id="HFS4043657.1"
                     /translation="MDRHRRHFSIRPFNACLSGSLCRTFRLHFVVTPALFLASNSYSL
                     SRSLSWNS"
     gene            23612..24583
                     /gene="manX"
                     /locus_tag="ACHY1N_001321"
     CDS             23612..24583
                     /gene="manX"
                     /locus_tag="ACHY1N_001321"
                     /EC_number="2.7.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HFS4043658.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIVVDKEHYEVIAGVNIPMLVETL
                     MARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPAAAAPKAAPTPAKPMGPND
                     YMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTA
                     HVVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQ
                     VNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISKIDK"
     gene            24646..25446
                     /gene="manY"
                     /locus_tag="ACHY1N_001322"
     CDS             24646..25446
                     /gene="manY"
                     /locus_tag="ACHY1N_001322"
                     /EC_number="2.7.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HFS4043659.1"
                     /translation="MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVAL
                     SVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD"
     gene            25459..26310
                     /gene="manZ"
                     /locus_tag="ACHY1N_001323"
     CDS             25459..26310
                     /gene="manZ"
                     /locus_tag="ACHY1N_001323"
                     /EC_number="2.7.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020804907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HFS4043660.1"
                     /translation="MVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSR
                     ITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     ACGLLGL"
     gene            26365..26823
                     /gene="yobD"
                     /locus_tag="ACHY1N_001324"
     CDS             26365..26823
                     /gene="yobD"
                     /locus_tag="ACHY1N_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 family protein"
                     /protein_id="HFS4043661.1"
                     /translation="MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGR
                     IDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFA
                     NVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ"
     gene            27252..27818
                     /gene="mntP"
                     /locus_tag="ACHY1N_001325"
     CDS             27252..27818
                     /gene="mntP"
                     /locus_tag="ACHY1N_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HFS4043662.1"
                     /translation="MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFG
                     AVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRR
                     HGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGS
                     IIGKKAEILGGLVLIGIGVQILWTHFHG"
     gene            complement(27815..28624)
                     /gene="rlmA"
                     /locus_tag="ACHY1N_001326"
     CDS             complement(27815..28624)
                     /gene="rlmA"
                     /locus_tag="ACHY1N_001326"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HFS4043663.1"
                     /translation="MSFSCPLCHQPLSREKNSYICPQRHQFDMAKEGYVNLLPVQHKR
                     SRDPGDSAEMIQARRAFLDAGHYQPLRDAIVAQLRERLDEKATAVLDIGCGEGYYTHA
                     FADVLPEITTFGLDVSKVAIKAAAKRYPQVTLCVASSHRLPFSDTSMDAIIRIYAPCK
                     AEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLEGFTLQQSDELCY
                     PMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQRSY"
     gene            complement(28790..28999)
                     /gene="cspE"
                     /locus_tag="ACHY1N_001327"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(28790..28999)
                     /gene="cspE"
                     /locus_tag="ACHY1N_001327"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HFS4043664.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            complement(29012..29155)
                     /gene="yobF"
                     /locus_tag="ACHY1N_001328"
     CDS             complement(29012..29155)
                     /gene="yobF"
                     /locus_tag="ACHY1N_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2627 domain-containing protein"
                     /protein_id="HFS4043665.1"
                     /translation="MCGIFSKEVLSKHVDVEYRFSAEPYIGASCSNVSVLSMLCLRAK
                     KTI"
     gene            complement(29825..30112)
                     /gene="yebO"
                     /locus_tag="ACHY1N_001329"
     CDS             complement(29825..30112)
                     /gene="yebO"
                     /locus_tag="ACHY1N_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebO family protein"
                     /protein_id="HFS4043666.1"
                     /translation="MNEVVNSGVMNIASLVVSVVVLLIGLILWFFINRASSRTNEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKADKKTVESQKSVEDEDIIRLVAER"
     gene            complement(30187..30330)
                     /gene="mgrB"
                     /locus_tag="ACHY1N_001330"
     CDS             complement(30187..30330)
                     /gene="mgrB"
                     /locus_tag="ACHY1N_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HFS4043667.1"
                     /translation="MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQF
                     IPW"
     gene            30489..30728
                     /gene="yobH"
                     /locus_tag="ACHY1N_001331"
     CDS             30489..30728
                     /gene="yobH"
                     /locus_tag="ACHY1N_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobH family protein"
                     /protein_id="HFS4043668.1"
                     /translation="MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAGLGLQCTYLT
                     ARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG"
     gene            complement(30871..31662)
                     /gene="kdgR"
                     /locus_tag="ACHY1N_001332"
     CDS             complement(30871..31662)
                     /gene="kdgR"
                     /locus_tag="ACHY1N_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HFS4043669.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMREISR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDLDEV
                     KQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQMGYHDYPF"
     gene            31839..33212
                     /gene="yebQ"
                     /locus_tag="ACHY1N_001333"
     CDS             31839..33212
                     /gene="yebQ"
                     /locus_tag="ACHY1N_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416342.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4043670.1"
                     /translation="MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIAT
                     DLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSD
                     SLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
                     AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLL
                     ITALSGFAQGQSLTLIAAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICT
                     SVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAG
                     LLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRE
                     RSGGASGMLGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACVSGLRI
                     TQPRSRA"
     gene            complement(33258..34139)
                     /gene="htpX"
                     /locus_tag="ACHY1N_001334"
     CDS             complement(33258..34139)
                     /gene="htpX"
                     /locus_tag="ACHY1N_001334"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HFS4043671.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGF
                     GGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFS
                     RHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTH
                     PPLDKRIEALRTGEYLK"
     gene            complement(34330..36378)
                     /gene="prc"
                     /locus_tag="ACHY1N_001335"
     CDS             complement(34330..36378)
                     /gene="prc"
                     /locus_tag="ACHY1N_001335"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HFS4043672.1"
                     /translation="MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGD
                     ELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
                     ELNALWDSKVKFDELSLKLAGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAI
                     SVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLT
                     RERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDL
                     RSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTA
                     FGPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRL
                     ARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
                     "
     gene            complement(36398..37096)
                     /gene="proQ"
                     /locus_tag="ACHY1N_001336"
     CDS             complement(36398..37096)
                     /gene="proQ"
                     /locus_tag="ACHY1N_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707288.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0033592 - RNA strand annealing activity
                     [Evidence IEA];
                     GO_function: GO:0034057 - RNA strand-exchange activity
                     [Evidence IEA];
                     GO_process: GO:0010608 - post-transcriptional regulation
                     of gene expression [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HFS4043673.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVD
                     RVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQK
                     PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLN
                     SGMSLIVRAEHLVF"
     gene            complement(37193..37690)
                     /gene="msrC"
                     /locus_tag="ACHY1N_001337"
     CDS             complement(37193..37690)
                     /gene="msrC"
                     /locus_tag="ACHY1N_001337"
                     /EC_number="1.8.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine (R)-S-oxide reductase"
                     /protein_id="HFS4043674.1"
                     /translation="MNKTEFYADLNRDFNALMAGETSFLATLANTSALLYERLTDVNW
                     AGFYLLEDDTLVLGPFQGKIACVRIPVGRGVCGTAVARNQVQRIEDVHAFDGHIACDA
                     ASNSEIVLPLVVKNQIIGVLDIDSTVFGRFTDEDEQGLRQLVAQLEKVLATTDYKKFF
                     ASVAG"
     gene            37820..39103
                     /gene="yebS"
                     /locus_tag="ACHY1N_001338"
     CDS             37820..39103
                     /gene="yebS"
                     /locus_tag="ACHY1N_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HFS4043675.1"
                     /translation="MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEIN
                     SHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANV
                     MQGIWQMTKQGDTITGAMVFFCVIGAPLILVSSIAYLWFGNRLGMNLRPVLLMLERLK
                     EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFY
                     PQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVL
                     LLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFDD"
     gene            39072..41705
                     /gene="yebT"
                     /locus_tag="ACHY1N_001339"
     CDS             39072..41705
                     /gene="yebT"
                     /locus_tag="ACHY1N_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-binding membrane homeostasis protein YebT"
                     /protein_id="HFS4043676.1"
                     /translation="MSQETPASTTEAQIKNKRRISPFWLLPFIALMIAGWLIWDSYQD
                     RGNTVTIDFMSADGIVPGRTPVRYQGVEVGTVQDISLSDDLRKIEVKVSIKSDMKDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKEQDHFVALDTQPKYRLDNGD
                     LMIHLQAPDLGSLNSGSLVYFRKIPVGKVYDYAINPNKQGVVIDVLIERRFTDLVKKG
                     SRFWNVSGVDANVSISGAKVKLESLAALVNGAIAFDSPEESKPAEAEDTFGLYEDLAH
                     SQRGVIIKLELPSGAGLTADSTPLMYQGLEVGQLTKLDLNPGGKVTGEMTVDPSVVTL
                     LRENTRIELRNPKLSLSDANLSALLTGKTFELVPGDGEPRKEFVVVPGEKALLHEPDV
                     LTLTLTAPESYGIDAGQPLILHGVQVGQVIDRKLTSKGVTFTVAIEPQHRELVKGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWINGGIRILPGDKGEMKASYPLYANLEKALENS
                     LSDLPTTTVSLSAETLPDVQAGSVVLYRKFEVGEVITVRPRANAFDIDLHIKPEYRNL
                     LTSNSVFWAEGGAKVQLNGSGLTVQTSPLSRALKGAISFDNLSGASASQRKGDKRILY
                     ASETAARAVGGQITLHAFDAGKLAVGMPIRYLGIDIGQIQTLDLITARNEVQAKAVLY
                     PEYVQTFARGGTRFSVVTPQISAAGVEHLDTILQPYINVEPGRGNPRRDFELQEATIT
                     DSRYLDGLSIIVEAPEAGSLGIGTPVLFRGLEVGTVTGMTLGTLSDRVMIAMRISKRY
                     QHLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQEGK
                     HFLLQESEPKEWREWGTALPK"
     gene            41785..43224
                     /gene="rsmF"
                     /locus_tag="ACHY1N_001340"
     CDS             41785..43224
                     /gene="rsmF"
                     /locus_tag="ACHY1N_001340"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HFS4043677.1"
                     /translation="MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVN
                     TLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADDNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHA
                     NISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     QEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDAVEFLPLGD
                     LFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPFSPVKD
                     REAGQIRQAAASVGLNWDGNLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHN
                     KGYRWQHEAVIALATPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPI
                     GLAKRIGSRLKNSYPRELVRDGKLFTGNA"
     gene            43342..43578
                     /gene="yebV"
                     /locus_tag="ACHY1N_001341"
     CDS             43342..43578
                     /gene="yebV"
                     /locus_tag="ACHY1N_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebV family protein"
                     /protein_id="HFS4043678.1"
                     /translation="MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAW
                     DAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA"
     gene            43683..43874
                     /gene="yebW"
                     /locus_tag="ACHY1N_001342"
     CDS             43683..43874
                     /gene="yebW"
                     /locus_tag="ACHY1N_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HFS4043679.1"
                     /translation="MFALVLFVCYLDGGCEDIVVDVYNTEQQCLYSMSDQRIRHGGCF
                     PIEDFIDGFWRPAQEYGDF"
     gene            complement(43875..44531)
                     /gene="pphA"
                     /locus_tag="ACHY1N_001343"
     CDS             complement(43875..44531)
                     /gene="pphA"
                     /locus_tag="ACHY1N_001343"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416352.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HFS4043680.1"
                     /translation="MKQPAPVYQRIAGHQWRHIWLSGDIHGCLEQLRRKLWHCGFDPW
                     RDLLISVGDVIDRGPQSLRCLQLLEQHWVRAVRGNHEQMAMDALASQQMSLWLMNGGD
                     WFIALADNQQKQAKTALEKCQHLPFILEVHSRTGKHVIAHADYPDDVYEWQKDVDLHQ
                     VLWSRSRLGERQKGQGITGADHFWFGHTPLRHRVDIGNLHYIDTGAVFGGELTLVQLQ
                     "
     gene            complement(44927..45268)
                     /gene="yebY"
                     /locus_tag="ACHY1N_001344"
     CDS             complement(44927..45268)
                     /gene="yebY"
                     /locus_tag="ACHY1N_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HFS4043681.1"
                     /translation="MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEV
                     MLTCRPGNALYVINPSTLVQYPLNDIAQKEVASGKTKAQPISVIQIDDPNNPGEKMSL
                     APFIERAEKLC"
     gene            complement(45281..46153)
                     /gene="copD"
                     /locus_tag="ACHY1N_001345"
     CDS             complement(45281..46153)
                     /gene="copD"
                     /locus_tag="ACHY1N_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HFS4043682.1"
                     /translation="MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLAKRFL
                     RLQQHAAVWSLISATAMLAVQGGLMGTGWADVFSPNIWQAVLQTQFGGVWLWQIVLAL
                     VTLIVALMQPRNMPRLLFMLTTAQFILLAGIGHATLNEGVTAKIHQTNHAIHLICAAA
                     WFGGLLPVLWCMQLIKGRWRHQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPT
                     LTTYWGQLLLLKAILVMIMVVIALANRYVLVPRMRQDEDRAAPWFEWMTKLEWAIGAV
                     VLVIISLLATLEPF"
     gene            complement(46157..46531)
                     /gene="yobA"
                     /locus_tag="ACHY1N_001346"
     CDS             complement(46157..46531)
                     /gene="yobA"
                     /locus_tag="ACHY1N_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HFS4043683.1"
                     /translation="MTSTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAA
                     PQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYT
                     VDWHVVSVDGHKTKGHYTFSVK"
     gene            46670..46900
                     /gene="holE"
                     /locus_tag="ACHY1N_001347"
     CDS             46670..46900
                     /gene="holE"
                     /locus_tag="ACHY1N_001347"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HFS4043684.1"
                     /translation="MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQ
                     PEHLRSWFRERLIAHRLASVNLSRLPYEPKLK"
     gene            47002..47658
                     /gene="yobB"
                     /locus_tag="ACHY1N_001348"
     CDS             47002..47658
                     /gene="yobB"
                     /locus_tag="ACHY1N_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein YobB"
                     /protein_id="HFS4043685.1"
                     /translation="MSFWKVAAAQYEPRKTSLTEQVAHHLEFVRAAARQQCQLLVFPS
                     LSLLGCDYSRRALPAPPDLSLLDPLCYAATTWRMTIIAGLPVEYNDRFIRGIAVFAPW
                     RKTPGIYHQSHGACLGRRSRTITVVDEQPQGMDMDPTCSLFTTGQCLGEPDLLASARR
                     LQFFSHQYSIAVLMANARGNSALWDEYGRLIVRADRGSLLLVGQRSSQGWQGDIIPLR
                     "
     gene            47682..48344
                     /gene="exoX"
                     /locus_tag="ACHY1N_001349"
     CDS             47682..48344
                     /gene="exoX"
                     /locus_tag="ACHY1N_001349"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HFS4043686.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPIS
                     PQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKL
                     ARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
                     MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLE
                     NT"
     gene            complement(48341..50401)
                     /gene="ptrB"
                     /locus_tag="ACHY1N_001350"
     CDS             complement(48341..50401)
                     /gene="ptrB"
                     /locus_tag="ACHY1N_001350"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HFS4043687.1"
                     /translation="MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQEN
                     SYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQS
                     AFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNL
                     ETGNWYPELLDNVEPSFVWANDSWTFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYE
                     EKDDTYYVSLHKTTSKHYVVIHLASATTSEVRLLDAEMADAEPFVFLPRRKDHEYSLD
                     HYQHRFYLRSNRHGKNFGLYRTRLRDEQQWEELIPPRDNIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFDAANYRSEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVY
                     GYGSYGASIDADFSFSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKKNTFNDY
                     LDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTML
                     DESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDDHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPA
                     TPAD"
     gene            complement(50610..51269)
                     /gene="yebE"
                     /locus_tag="ACHY1N_001351"
     CDS             complement(50610..51269)
                     /gene="yebE"
                     /locus_tag="ACHY1N_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HFS4043688.1"
                     /translation="MANWLNQLQSLLGQSSSSTSSSADQGLGKLLVPGALGGLAGLLV
                     ANKSARKLLTKYGTNALLVGGGAVAGTVLWNKYKDKIRAAHQDEPQFGAQSTPLDERT
                     ERLILALVFAAKSDGHIDAKERAAIDQQLREAGVEEQGRVLIEQAIEQPLDPQRLATG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVRDGIERDLEQQKRTLA
                     E"
     gene            complement(51596..51952)
                     /gene="yebF"
                     /locus_tag="ACHY1N_001352"
     CDS             complement(51596..51952)
                     /gene="yebF"
                     /locus_tag="ACHY1N_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YebF"
                     /protein_id="HFS4043689.1"
                     /translation="MKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIA
                     ASVKRDYQQNRVARWADDQKIVGQADPVAWVSLQDIQGKDDKWSVPLTVRGKSADIHY
                     QVSVDCKAGMAEYQRR"
     gene            complement(52019..52309)
                     /gene="yebG"
                     /locus_tag="ACHY1N_001353"
     CDS             complement(52019..52309)
                     /gene="yebG"
                     /locus_tag="ACHY1N_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HFS4043690.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTN
                     SPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA"
     gene            52443..53621
                     /gene="purT"
                     /locus_tag="ACHY1N_001354"
     CDS             52443..53621
                     /gene="purT"
                     /locus_tag="ACHY1N_001354"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HFS4043691.1"
                     /translation="MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRY
                     SDAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVV
                     PCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVAAIGYPCIVKPVMSS
                     SGKGQTFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQN
                     VTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
                     "
     gene            complement(53677..54318)
                     /gene="kdgA"
                     /locus_tag="ACHY1N_001355"
                     /gene_synonym="eda"
     CDS             complement(53677..54318)
                     /gene="kdgA"
                     /locus_tag="ACHY1N_001355"
                     /gene_synonym="eda"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFS4043692.1"
                     /translation="MKNWKTSAESILTTGPVVPVIVVKKLEHAVPMAKALVAGGVRVL
                     EVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCP
                     TGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL"
     gene            complement(54355..56166)
                     /gene="edd"
                     /locus_tag="ACHY1N_001356"
     CDS             complement(54355..56166)
                     /gene="edd"
                     /locus_tag="ACHY1N_001356"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004456 - phosphogluconate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HFS4043693.1"
                     /translation="MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWM
                     PIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMA
                     RLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGEL
                     DWREGAEKSLDSNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVV
                     FESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE
                     PHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF"
     gene            complement(56401..57876)
                     /gene="zwf"
                     /locus_tag="ACHY1N_001357"
     CDS             complement(56401..57876)
                     /gene="zwf"
                     /locus_tag="ACHY1N_001357"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFS4043694.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQLNPDTR
                     IIGVGRADWDKAAYTKVVREALETFMKETIDEGLWDTLSARLDFCNLDVNDTAAFSRL
                     GAMLDQKNRITINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSQEIN
                     DQVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDKAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     YNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPG
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            58214..59083
                     /gene="hexR"
                     /locus_tag="ACHY1N_001358"
                     /gene_synonym="yebK"
     CDS             58214..59083
                     /gene="hexR"
                     /locus_tag="ACHY1N_001358"
                     /gene_synonym="yebK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HexR"
                     /protein_id="HFS4043695.1"
                     /translation="MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAAMALEA
                     NVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVESYTGKIFESA
                     MATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYS
                     DDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKES
                     RFDKQLLNLSDDR"
     gene            59211..60653
                     /gene="pyk"
                     /locus_tag="ACHY1N_001359"
     CDS             59211..60653
                     /gene="pyk"
                     /locus_tag="ACHY1N_001359"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFS4043696.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGY
                     LMSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(60784..61755)
                     /gene="lpxM"
                     /locus_tag="ACHY1N_001360"
                     /gene_synonym="msbB"
     CDS             complement(60784..61755)
                     /gene="lpxM"
                     /locus_tag="ACHY1N_001360"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416369.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009276 - Gram-negative-bacterium-type
                     cell wall [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HFS4043697.1"
                     /translation="METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFR
                     DPILARLGRFAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMAMMAE
                     LAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHT
                     IARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(61875..63197)
                     /gene="mepM"
                     /locus_tag="ACHY1N_001361"
     CDS             complement(61875..63197)
                     /gene="mepM"
                     /locus_tag="ACHY1N_001361"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HFS4043698.1"
                     /translation="MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRD
                     ATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAIPQDELDDKIAGEAGVHEYVVST
                     GDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRE
                     TRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQ
                     WQMDFRKLKKGDEFAVLMSREMLDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRN
                     GTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGE
                     VVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGP
                     HLHYEVWINQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD"
     gene            complement(63213..64145)
                     /gene="znuA"
                     /locus_tag="ACHY1N_001362"
     CDS             complement(63213..64145)
                     /gene="znuA"
                     /locus_tag="ACHY1N_001362"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006829 - zinc ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HFS4043699.1"
                     /translation="MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIAD
                     GVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPEAKQV
                     TIAQLEDVKPLLMKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
                     KLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFG
                     LTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMG
                     TLDPLGTNIKLGKTSYSEFLSQLANQYASCLKGD"
     gene            64224..64979
                     /gene="znuC"
                     /locus_tag="ACHY1N_001363"
     CDS             64224..64979
                     /gene="znuC"
                     /locus_tag="ACHY1N_001363"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015633 - ABC-type zinc transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006829 - zinc ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HFS4043700.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKS
                     TLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDIL
                     PALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS"
     gene            64976..65761
                     /gene="znuB"
                     /locus_tag="ACHY1N_001364"
     CDS             64976..65761
                     /gene="znuB"
                     /locus_tag="ACHY1N_001364"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HFS4043701.1"
                     /translation="MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVAFGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQLAIDTLLGIMAHSALSLGLVVVS
                     LMSNIRVDLMAYLFGDLLAVTPEDLIAIAIGVVIVVAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     LVGMVAVTGGLTFSAFYDTPAGPSVVLCAALLFILSMMKKQAS"
     gene            complement(65908..66918)
                     /gene="ruvB"
                     /locus_tag="ACHY1N_001365"
     CDS             complement(65908..66918)
                     /gene="ruvB"
                     /locus_tag="ACHY1N_001365"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFS4043702.1"
                     /translation="MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIF
                     IKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPE
                     MP"
     gene            complement(66927..67538)
                     /gene="ruvA"
                     /locus_tag="ACHY1N_001366"
     CDS             complement(66927..67538)
                     /gene="ruvA"
                     /locus_tag="ACHY1N_001366"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFS4043703.1"
                     /translation="MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL"
     gene            complement(67677..67742)
                     /gene="yobI"
                     /locus_tag="ACHY1N_001367"
     CDS             complement(67677..67742)
                     /gene="yobI"
                     /locus_tag="ACHY1N_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response small protein YobI"
                     /protein_id="HFS4043704.1"
                     /translation="MYIFITHFFTEYVIFKYLLPI"
     gene            67813..68415
                     /gene="yebB"
                     /locus_tag="ACHY1N_001368"
                     /pseudo
     CDS             67813..68415
                     /gene="yebB"
                     /locus_tag="ACHY1N_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416376.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
     gene            complement(68417..68938)
                     /gene="ruvC"
                     /locus_tag="ACHY1N_001369"
     CDS             complement(68417..68938)
                     /gene="ruvC"
                     /locus_tag="ACHY1N_001369"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HFS4043705.1"
                     /translation="MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(68973..69713)
                     /gene="yebC"
                     /locus_tag="ACHY1N_001370"
     CDS             complement(68973..69713)
                     /gene="yebC"
                     /locus_tag="ACHY1N_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4043706.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAVDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(69742..70194)
                     /gene="nudB"
                     /locus_tag="ACHY1N_001371"
     CDS             complement(69742..70194)
                     /gene="nudB"
                     /locus_tag="ACHY1N_001371"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008828 - dATP diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0019177 - dihydroneopterin triphosphate
                     pyrophosphohydrolase activity [Evidence IEA];
                     GO_process: GO:0046656 - folic acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HFS4043707.1"
                     /translation="MEDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE
                     EGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESW
                     FCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA"
     gene            complement(70312..72084)
                     /gene="aspS"
                     /locus_tag="ACHY1N_001372"
     CDS             complement(70312..72084)
                     /gene="aspS"
                     /locus_tag="ACHY1N_001372"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004815 - aspartate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006422 - aspartyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFS4043708.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTII
                     NRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQI
                     DEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMI
                     FFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEE
                     EQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANPTALAELSIQVVKKAENN"
     gene            72394..72960
                     /gene="yecD"
                     /locus_tag="ACHY1N_001373"
     CDS             72394..72960
                     /gene="yecD"
                     /locus_tag="ACHY1N_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFS4043709.1"
                     /translation="MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKF
                     RASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLPENWWQHPAALGATDSDIEIIKR
                     QWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS
                     AEQHNNSINHIYPRIARVRSVEEILHAL"
     gene            72957..73052
                     /locus_tag="ACHY1N_001374"
                     /pseudo
     CDS             72957..73052
                     /locus_tag="ACHY1N_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310605.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            73314..73562
                     /locus_tag="ACHY1N_001375"
     CDS             73314..73562
                     /locus_tag="ACHY1N_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI-like family protein"
                     /protein_id="HFS4043710.1"
                     /translation="MRIEICIAKEKMTKMPTGAVDALKDELTRRISKRYDDVEVIIKA
                     TSNDALSVTRITDKDSAKTFVQETLKDTWESADEWFVH"
     gene            73699..73782
                     /locus_tag="ACHY1N_001376"
                     /pseudo
     CDS             73699..73782
                     /locus_tag="ACHY1N_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            complement(73808..74398)
                     /locus_tag="ACHY1N_001377"
     CDS             complement(73808..74398)
                     /locus_tag="ACHY1N_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001132166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bfpT-regulated chaperone"
                     /protein_id="HFS4043711.1"
                     /translation="MPMKTTGTSFSSFGVSCHRENSFRNPFRGKNDEVIKCSIGERTI
                     RFSVDKFSGNILDTVRRQSAKNIDGWVKDEQMVYPSRVINQEIDNYCLQRNEKITTEV
                     KQRVFSLVSQKYQLSLDIKAAQSSINHVIMGNASFGKKIDALCDGMSRDVKNRTSDSI
                     ANLLADKFYQKHIDSDIDIVKLRNEIPDYLRFAIQA"
     gene            74582..75232
                     /locus_tag="ACHY1N_001378"
     CDS             74582..75232
                     /locus_tag="ACHY1N_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1076 domain-containing protein"
                     /protein_id="HFS4043712.1"
                     /translation="MPVILNFSNGSVLPENELEALRHIARSNQNDTITIGSRNMRLHY
                     IQFMDGFSVEPIPGGLRDRLGARETHHLADSLTRQLNGGNTFLQAYSLYLEQRHAAPL
                     VQESVIKTLLDRINLNAFPVSLQDFSCTEEYLNCPITLHIPETGVFVRNALSSEICAL
                     YDQKALTELIRRNALHPFSREPFSPEMIIRKETCHFNIAKQCFCAFPIYTLQQNSI"
     gene            75311..76369
                     /gene="espW"
                     /locus_tag="ACHY1N_001379"
     CDS             75311..76369
                     /gene="espW"
                     /locus_tag="ACHY1N_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector EspW"
                     /protein_id="HFS4043713.1"
                     /translation="MPKISSVVSSCYYLFREHQQLSNETTMTNSASRRIVHKEHGISL
                     KSVPVWLATAKTPLALLNGKHTRSHSFIIAGTPGMGGRSGAQYYAINSDDKRSRIDID
                     SLFLKKLNNARNQNKFSIDVKETVIKLQGQKFTCIEDFHKKYSEIRLKTNSNIQQKQI
                     TDEVKSLTYLIPSEKKEMWIYKNNGKDNAKPNLGERDVRMFENISPDDTDKITGRKFS
                     ELGEYLYSGNVIKLSQLSIRYLPNINSISLIETKQSLLLHRLYSDEVLQRNGTLIPTP
                     LHEEKSIPAANIKTMLNNIPTYKMLPPFTETQGNCSSGAATFLRKSGTEEKDILACSP
                     RNYGLHHNIKTWDPLVRN"
     gene            complement(76497..>76768)
                     /locus_tag="ACHY1N_001380"
     CDS             complement(76497..>76768)
                     /locus_tag="ACHY1N_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004842 - ubiquitin-protein transferase
                     activity [Evidence IEA];
                     GO_process: GO:0044403 - biological process involved in
                     symbiotic interaction [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="T3SS effector NleG family protein"
                     /protein_id="HFS4043714.1"
                     /translation="FRPDSNHFSCPESFLTCPITLDTPENGVFMRNSRGAEICSLYDK
                     DALVQLVETGGAHPLSREPITESMIMRKDECHFDSKKEAFVASDA"
BASE COUNT        18963 a        19590 c        18618 g        19597 t
ORIGIN      
        1 ggaagaagtt tttgtaagcc cgctcaaggt ctttcagtga ctgttgcaat ggctgtgagg
       61 gagaatcttt aagccattgc gtttcagtgg catttttcca ctcaaccagc caggaagcca
      121 ttttcccgta agggatgtat ttattaccgg cctcatgatt ctcattctga agcgccagag
      181 cacgattgaa aacgaaacga catgcgcctg cgaagcgcct catttcacac tcctgttgat
      241 cacctggtct taactggaat ttaaatgcct gtagtcgttt cacaggccaa atgatacttt
      301 ggtctgtgaa aaaagaaacc gatatccggc gtggaaggca ttgtgttttc ctgatgcatg
      361 ttcacctggt ctttgtcacc agatacagac gtcagatttt tgaccatgac gcgacagaaa
      421 aactacgcgc ttacttttca aatgtatgtg ctgattttga agctgaactt gttgaaatgg
      481 atggcgaacc agatcacgtc catttgttaa ttaactatcc tcccaaactg gcgatatcca
      541 gtctggtaaa cagcctcaaa ggcgtatcgg gtaggttact gcgacgagat cgaccagata
      601 ttgcagtcag gtattactac aaaggcgttt tgtggagtcc tggctatttt gccagtagct
      661 gcggaggtgc gccaatatcc gtcatccgcc aatacattga acaacagcaa acacctggtt
      721 aggtggaaaa ccgcgcctta tatccccgcc ctgaaggacg gggttttacg gcgcaccgga
      781 taagaacgca cggtattcac cagatctttt atcacttcag ccgccacttc tggcaccagc
      841 aaagtcatcg gcgtctctgt ttcataatcg acagaaacgc cattgctgtt attggtgacg
      901 gtcacggtat acgttgcttt gcccatgatt catttcccgt tatgaatgac tttccgttgt
      961 tgcgcacctt ccatcaggac ttcaggagcc acgaagaagt caatgttgaa ataagtatcg
     1021 tcagtcatgg cttcaatgtt gtgccacttt tctggaggga acaccgcaaa ctgccccgct
     1081 tcgataagga tcacctgatc aggctctgca ctgtgttcat cagcgtagcc gagatatttg
     1141 accgccccat gcataacgga aaggcgtggg taaacccccg ggcgcgttcc tttatcaaga
     1201 tgacgttcga atattccggc aggcgcagtt tgtttattcc agaaaggcgt tgagcgcgta
     1261 tgaatataat tctgtgggat ttgcagcatc tttttccctc cttcgttgaa tgcgctgaaa
     1321 acggtattcc agccgtttca gagtacgcct gataatttgc attttaaata ccatttattg
     1381 gttatttttt agcatcatat cagagaagaa tcagggagga ttacaagtgg gaagcccgcg
     1441 acaacgcggg ctgaatgtat caggattgca gcgtcgccag tcgggcagcg aaacccacga
     1501 acatcaaacc aatcagtgag ttgcccactt tagtcagttt ctttttggta cgtatgtact
     1561 gcgtgacaaa agcaccagaa ataatcagga agctcaaata gcagaaactc accagttcca
     1621 gcgtcgtcgc cagaataaag aatgaaattc ccgtatgtgg ggcattaaca tcgataaact
     1681 gtacgaaaaa cgacacatag aacaaaatgg ctttcggatt agtcaggctc aaaattaacg
     1741 cgcgtttaaa aatagcaccg tattggggct catcggattt ggcctcgtta tttttaccct
     1801 tcagggtcgc gtagagaatt ttactcccca gatagagcaa ataaaacgca ccaagataac
     1861 gtataatgtt gaataatatc ggggtggtct taattaatgt cgccactcca gcccatgcca
     1921 gaaacatcaa taccgcatcg ccaataaata caccgcaggc cgcaagataa ccgcctttca
     1981 taccgctact gacgctattt ttgagtacaa acagggtatt tggccctggc accaacacaa
     2041 taaaaatggc cccaaccaga taggtccagt aattcagaac cccgtattca gcgaacacat
     2101 taacctcttt aattatcttt cgatcatgcg cgattaaagg tgaatatgct aaccaatctg
     2161 tagcggctta gaaaggagaa aatcaggttt taacccgata tcaacccgat aattgaataa
     2221 ttaatcaggc atgctccagt gaaaaattct ggtagtgctc ggcaaaatac tggcgtaaaa
     2281 attctaccgt tatccgcact ttcgctgacg tcgccagcct tgaaacataa acggcccaga
     2341 cgttcgctgg ctggtaatat tccggtagca cttgcactaa atgaccactg gcaatgtttt
     2401 cgctaacatc ccaccaggaa cgcagagcaa tcccctgccc atcgagacac cactgatgga
     2461 caatttctcc atgattagac gacagtgggc cggtgacttt aatcgcatgg tggccttctt
     2521 tattgcgtaa ttgccagaca ccaaaaggat gatcgcgctc tttaatgacc aagcacggca
     2581 atgcagaaag atcggttaaa tgtttcggcg cgccatgttg cgcaataaat tccggcgacg
     2641 cgcagagaat gcggtaattg gtcgccagtt tgcgggcgat taaattaggg gcgatgtcat
     2701 cgccaatgcg aatatcgaga tcgacacctt cattgaccaa atcgaccagt cggtcttcca
     2761 catcaaaacg taattccagt tgcggatacg ccttcgccag cgctgataac gccggagcca
     2821 ccacctgtcg tccaaaacca aagctgctga taatacgcag catcccctgg ggcacctgac
     2881 gcacgtcaga aagttcgtcc atcatctgac cgacatcctg caaaatccgc tgcgcccatt
     2941 cataaatccg ctctccttct tcggtaatgg tgacgcggcg ggtggtgcgg tgtaacaaca
     3001 ccacgtttag cgtttgctcc agcaaggcga tgcgcttgct gacgaacgcc ggtgaaacgc
     3061 ccagttcttc cgccacggcg gcaaaaccag cccgacgagc caccagcata aagacgcgca
     3121 aatcattcag cagcggtaaa ttattcatga ttcgtgtttt atgtttcacc agttacgggg
     3181 attaattcct tttcagtcaa ttataggatg gtgatgttgt caattttgat ggtcaggaag
     3241 tgagaaccca atgatgaaaa cgatgcgtat tgctgcgatc ccgggagacg ggattggcaa
     3301 agaagtcctt cctgaaggga ttcgcgtgtt acaggctgcc gctgagcgct ggggcttcga
     3361 cttgagtttt gagcaaatgg agtgggcgag ctgcgagtat tacagccatc acggtaaaat
     3421 gatgccggac gactggcatg agcaacttag ccgtttcgac gccatctatt ttggtgccgt
     3481 cggctggccg gataccgttc cggaccatat ttcgttgtgg ggttcgctgc tgaaatttcg
     3541 tcgtgaattc gaccagtacg tcaacctgcg cccggttcgt ctctttcctg gcgttccctg
     3601 cccgctggcg ggaaaacagc ctggcgacat cgatttttac gtggtcaggg aaaacaccga
     3661 aggcgaatat tcctcgctcg gcggtagagt gaatgaaggt acagagcatg aagtcgtcat
     3721 tcaggaatcg gtatttacgc gtcgtggtgt cgatcgcatt ttgcgttatg ccttcgaact
     3781 tgcgcaaagc cgcccacgta agacgctaac ttctgccact aaatcaaacg gtttagccat
     3841 cagcatgccg tactgggatg agcgagtgga agcaatggcc gagaattacc cggagatccg
     3901 ctgggacaag cagcatattg atattctctg cgcgcgtttt gtgatgcagc cggaacgctt
     3961 cgatgtggtg gtggcgtcca atttatttgg cgatatcctt tccgatcttg gcccggcctg
     4021 caccggcacc attggcattg ccccatccgc caacctgaat ccggaacgca ctttcccgtc
     4081 gctcttcgag ccagtccacg gttccgcgcc ggatatctac gggaaaaaca ttgctaaccc
     4141 tatcgccacg atttgggccg gtgcaatgat gctcgatttt ctcggcaatg gcgatgagcg
     4201 tttccagcaa gcgcataacg gtattctggc agcaattgaa gaagtgattg ctcacgggcc
     4261 gaaaacacct gatatgaaag gcaatgccac cacgccacag gttgccgacg cgatttgcaa
     4321 aattattttg cgttaaggtc aaaccagttt atttgaaccg cgtcactgac gcggtttttt
     4381 tattcgttct ttgcagtaaa taacctgcgt catttcacct tttattgttt ccgtttcgtg
     4441 ttttatggct ttccgtattc ttaattgttt aatttatgta acatgcaaat aatcaatttg
     4501 ttaaacacaa catacaactc attaccctgc aaataattac aactggcaaa agccagagac
     4561 gggcttttat gcccaggaga tgactcatga tgagcaatgt taagaaaaaa gatgtgccgc
     4621 tgataagcat cagcctggtg gccattcttt tcatcgcagc tgcattaagc cttttcccac
     4681 aacaatcggc cgacgcggcc aacgcaatat acacttttgt tacgcgtacg ttaggttccg
     4741 ccgtacaggt attggttttg ctggcaatgg gactggtgat ttatttagcc accagtaaat
     4801 acggcaatat tcgtcttggc gaaggaaaac cggaatacag cacgctctcc tggctgttta
     4861 tgtttatttg tgccggttta ggttcttcta cgctttattg gggggttgct gaatgggcct
     4921 attattatca aacgcctgga ttaaatatcg caccgcgttc acaacaggca ctcgaattta
     4981 gcgtccctta ctccttcttc cactggggca tcagcgcctg ggcaacttat acgctggcct
     5041 cattaatcat ggcttatcac tttcatgtgc gtaaaaacaa aggtctgagt ctttccggca
     5101 ttattgccgc gattaccggc gttcgcccgc aaggcccatg gggaaaactg gttgatttga
     5161 tgttcctgat cgccactgtc ggcgcactga ctatttccct tgttgtcacc gcagcaacct
     5221 ttactcgtgg actttccgcg ctgaccggtt tacccgataa cttcaccgtg caggcatttg
     5281 tgatcctgct ttccggcggc attttttgcc taagctcgtg gattggtatc aacaacggtt
     5341 tgcaacgtct gagcaaaatg gttggctggg gcgcgttcct gctgccatta ctggtgctga
     5401 ttgtcggccc aaccgaattt attaccaaca gcatcatcaa tgccatcggt ctgaccacgc
     5461 aaaacttcct gcaaatgagc ttattcaccg atccgcttgg cgatggttca tttacccgca
     5521 actggaccgt tttctactgg ctgtggtgga tctcatacac ccctggcgta gcaatgtttc
     5581 tcacccgcgt ttcccgcggt cgtaagatta aagaagttat ctggggactg atcctcggca
     5641 gcaccgtcgg ttgctggttc ttcttcggcg taatggaaag ctatgccatt catcagttta
     5701 tcaatggcgt aatcaacgtc ccacaggtgc tggaaacact gggcggcgaa acagctgtac
     5761 agcaagttct gatgtcgttg ccagccggta aattgttcct cgccgcatac ctgggcgtga
     5821 tgattatttt ccttgcctcg catatggatg cggtggccta caccatggct gcgaccagta
     5881 cgcgtaatct ccaggaaggt gacgatcctg accgtgggct gcgtcttttc tggtgcgtgg
     5941 tgatcactct gatcccgctt tccatcttgt ttaccggtgc ttcgctggaa acgatgaaaa
     6001 ccaccgtcgt gctcacagcc cttcccttcc tcgtcatttt actggtgaaa gtcggcggat
     6061 ttattcgctg gctgaaacag gattacgccg acattccggc tcatcaagtt gaacattatc
     6121 tcccgcagac accggttgaa gccctggaaa aaacgccagt gctccctgcg ggaaccgtat
     6181 tcaaaggcga caactgagcg ccatcatcct aacgataaag gtatccctat gagcaatctg
     6241 agccctgact ttgtactacc cgaaaattat tgcgctaacc cgcaagaggc gtggaccatt
     6301 cctgcccgtt tttataccga tcagaacgcg tttgaacacg aaaaagagaa cgtcttcgcc
     6361 aaaagctgga tttgcgtcgc tcacagcagc gaactggcga atgccaatga ttatgtgacg
     6421 cgtgagatca ttggcgaaag catcgtgctg gtacgcggtc gtgataaggt tttgcgcgcg
     6481 ttctataacg tgtgtccgca ccgtggtcat cagttgttga gcggtgaagg aaaagcaaaa
     6541 aatgtgatta cctgcccgta tcacgcatgg gcattcaaac tcgatggcaa cctggcccat
     6601 gcacgtaact gcgaaaacgt cgccaatttc gatagcgaca aagcgcaact ggttccggtg
     6661 cgtctggaag aatatgccgg attcgtcttc atcaacatgg accccaacgc caccagcgta
     6721 gaagatcaat tacccggcct gggcgcgaaa gtgctggaag cctgcccgga agtccacgat
     6781 ctgaaactgg cggcccgctt taccacccgc acgcctgcca actggaagaa cattgtcgat
     6841 aactatctcg agtgctatca ctgtggtccg gcgcatccag gtttctccga ctccgtacag
     6901 gttgatcgtt actggcacac catgcacggt aactggacgc tgcaatacgg tttcgccaaa
     6961 ccgtccgaac agtcgtttaa atttgaagag ggtacggatg cggcattcca cggtttctgg
     7021 ctgtggccgt gcacgatgct gaacgtcacc ccgatcaaag ggatgatgac ggtcatttat
     7081 gaattcccgg tggattctga aactaccctg caaaactacg atatttactt caccaatgaa
     7141 gagttaaccg acgagcaaaa atcgctgatt gagtggtatc gcgatgtgtt ccgtccggaa
     7201 gatttacgtc tggttgaaag cgtacagaaa gggctgaaat cgcgtggcta tcgtggtcag
     7261 gggcgcatca tggccgacag tagcggtagt ggcatttccg aacatggtat cgcccatttc
     7321 cataatctgc tggcgcaggt gtttaaggac taatgacatc ggcggcggta ttttccgccg
     7381 ctgggctgat ttttgatgga gtacagcaat gtcagactat caaatgtttg aagtacaggt
     7441 gagtcaggtg gaaccgctta ccgaacaggt gaaacgcttc acgctggtgg caaccgatgg
     7501 caaaccgctg cctgcgttca ccggaggaag tcacatcatt gtgcagatga gcgatggtga
     7561 taaccagtac agcaatgcgt attcactact gagttcgccg catgacacct cttgttatca
     7621 gattgccgtt cggctggagg aaaactcgcg cggcggttcc cgctttttgc atcagcaggt
     7681 aaaagtgggc gatcggttaa cgatttcaac gcctaataac ctgtttgcgc taattccctc
     7741 agccagaaag catctgttta tcgcgggcgg tattggtatc acccctttcc tgtcgcacat
     7801 ggcagagctg caacacagcg acgtcgactg gcagctacat tactgctcgc gaaatccaga
     7861 aagttgcgca tttcgtgatg agctagtcca gcatccgcag gctgagaaag ttcacttgca
     7921 tcactcatca accggaacac gactggaatt agcgcgatta ttggcggata tcgaacctgg
     7981 cacacacgtt tatacctgtg gtcccgaggc gctaaatgaa gcggtaagaa gtgaagctgc
     8041 gcgtctggac atcgtcgccg atacgctgca ctttgagcaa tttgctatcg aagacaaaac
     8101 cggcgatgcc tttaccctgg tgcttgcccg ttccggaaaa gagtttgtgg tgccggaaga
     8161 gatgactatt ttgcaggtta ttgaaaataa taaagccgcg aaagtggaat gtttatgtcg
     8221 tgaaggggta tgcggaacct gcgaaacagc aatactggaa ggtgaagctg accatcggga
     8281 tcagtatttt agcgatgaag agcgtgccag ccagcaaagt atgttgatct gttgttcgcg
     8341 tgcgaagggt aaacgcctgg tgttggattt gtagtttgcc aaagccggat gtggcgctga
     8401 gcgcgcccag tccggcttcg gaagatttta ctgcggatat tcctgcaata aattgtgtaa
     8461 tgcttccgcc atcagctcac cacgccagcc ggaaatcagc tccggcaaat tgttctgcgg
     8521 tttcagtttc cagtgccagt tcagcagttg gttgatttgc cgacgcgatg ccagcaattc
     8581 ggcgctgatc ttatgcgttt cgctcacgtc agtaatcagc gacttaatcg ctttaaacgc
     8641 tttacgataa ccaggcatgt ccatcaggtt aagcatcggc tgcggtaagg cctcttccgg
     8701 caatgtctgc gctttttcca ccagcgccag cagcgtttta ccgtgaaagc ggatttcgct
     8761 accggataaa cccaggctgt ccagttcgcc taaacttccc ggcatataac gcgcgaccga
     8821 ccacaaatgc tcttcacgca cgacaaagtt caccgccaga tcacgctctc gcgccttgcg
     8881 cagtcgccag tcggctaaca gttgcagaca ggccagttgg cgtgtgcgta actgccaggc
     8941 attggtgata tcacgccagg catcttccgg cgcaacgact tcctgacgac gcatttgcat
     9001 caggcggcat tcatccagcg ccgcaggtag ccagccggag gcctccgttt ctaccataag
     9061 cttggcggtg atcggtaaca gataccagac atccgccgct gcgtattcac actgacgttc
     9121 ggtcagcggt ctggccagcc agtcggtgcg cgattcactc ttgtccagcg taacgccgga
     9181 atactcttcc accatggaag cgaaacccca tgacatcggg cgtccgcaga aggcagcaag
     9241 gatttgcgtg tcaatcaagg gttgtggtaa ttcgccaaag acattgagga acacttccag
     9301 atcttcactg cctgcatgga gaaattttgt gatggacgga tcgcgcagga tcgctttcag
     9361 cggtgaccag tcggtgatcc cgagaggatc aattagcgcc agatgctcgc catcgaaaag
     9421 ttgaatcaac cccagctgcg ggtaataagt gcgcgtacga acaaattcag tatccagggc
     9481 tatcgccgga aaggcacgga cggcttcaca caaagaagcc agcgcatcgt ccgtggtaat
     9541 catttggtaa ttcaaattgt tttctcttta gtgggcgtca aaaaaaacgc cggattaacc
     9601 ggcgtctgac gactgactta acactcaggc tttattgtcc actttgccgc gcgcttcgtc
     9661 acgtaattct cgtcgcaaaa tttttccgac gttagatttc ggtaactcat cacgaaactc
     9721 caccagcttc ggtactttgt agcccgtgag ctgacggcgg caaaaggtca ccagtgactc
     9781 ttcggtaagc gatggatctt ttttcactac gaagattttc accgcttcac cactggagcc
     9841 ggaaggtacg ccaacagccg cgacttcctg tacgccagga tgctgcatga cgacatcttc
     9901 aatctcgttg ggatagacgt taaaaccgga aaccagaatc atgtcttttt tacgatcgac
     9961 aatgcgcagg aacccttctt catccatcac cgcgatgtcg ccggtgtgta accagccatt
    10021 tttgatgatc tcatctgtag catccggacg ctgccagtaa cccagcatca cctgcggtcc
    10081 tttgacacaa agctcacccg gttgacccgg tggtacttca ttatcatcat catccaccag
    10141 tttggcttcc gtcgacggca ccggcaaacc gatgctacca ctatgataat caatatcata
    10201 tgggttaacg ctgaccagcg gcgcacactc ggtaaggcca tagccttcca gcagatactg
    10261 tcctgtcagt ttcacccaac gctctgccac cacttgctgc actggcatcc ctccgcctgc
    10321 ggaaagatgc agactggaga aatccagctg ctggaactct ttattgttca gcaacgcatt
    10381 gaacaaggtg ttaacgcccg tgatagcggt aaacggatat ttcgctaact cttttaccaa
    10441 ccctggaata tcgcgcgggt tagtgataag caggttctgc ccacccagtt cgataaacag
    10501 caggcagtta atggtcaggg caaaaatgtg atacagcggc agcgccgtca ccaccagctc
    10561 tttgcccgga tgcaacagcg gaccataggt cgcgttaacc tgttccaggt tcgccagcat
    10621 attgcggtga gtcagcatcg cgcctttcgc cacaccagtg gtgccgccgg tgtattgcag
    10681 aaaagctaaa tcttccggca ccagttcggg tttgacgtac tgcatccggt agccgttatg
    10741 cagtgcgcta cgaaatgaaa tggcatctgg cagatggtat ttcggcacca aacgcttgat
    10801 gtatttaaca acgaaattga ctaccgtgcc ttttgccgta gatagctgat cgcccatacg
    10861 ggtcagaatt acgtgctgaa cggcggtttt atcaaccact ttttccagtg tgtgagcaaa
    10921 gttagacacg ataacaatcg ccgatgcgcc gctatcgtta agctgatgct caagctcacg
    10981 cggggtatac aacgggttaa cgtttacgac gatcatccct gcacgcaaaa tgccaaacag
    11041 cgccaccgga tattgcaata aattaggcat catcaacgca acgcgatcgc ctttcttcag
    11101 ccccaaccct tgttgcaaat aagcggcaaa cgcgcgactg cgttcttcca gcttgcggaa
    11161 ggtcattacc tcccccatat tcacaaacgc aggctgatcg gcgtagcgcg cgaccgactg
    11221 ctcaaacata tctaccagag attgataacg gtcagggttg atctccgtcg gaacgtccgc
    11281 gggataacgg ttaagccaaa ccttcttcaa ttcttcacct ctaaaatgcg tgttcgtcgt
    11341 catcgcaacc ccaaatgata tacatgccgt taacataata ttaactcatc ataccagctt
    11401 gataattacc caacgaaaag gttgcgaagc gcgtcactat ttatttttat ctttaccgta
    11461 agaatgcaga aacagcggac cagccgctgt ttctttttct ttaaaaacaa gcaattattc
    11521 agttacaact gtttgtactc tcgcgggacc gggattatac cagccccatc cgccgtagcc
    11581 atagggccag ccacgaccgc cataaaacca tggatcaatc ggctgaggcg gcataatcac
    11641 ctgctgggtt aaatgccaac gtttgtaacc cgttacttgc atcaccataa atttataggg
    11701 cgtattgccg attttgccgt caaccgcacc agtgattggc ccaactaccg taaccagttg
    11761 tccacggaaa tccaccgggt ccagaaaacc gttcacatcg gcataaatgc gaccgcgaga
    11821 aggttctccc agcgtcggtc tggctccgct gtccagcggt acggtagcaa tttccaggcg
    11881 ggttttccct tgctggtttt gtaccgcaac cactttgcca ccaaagcgtg cctcctgacc
    11941 aacgtacagc tgcggcgcac tcatcacccg aactaaatct tgttgcggcg tgggactgct
    12001 gcctttaatg gcgtccggca cagtgacaca accgctcagc attagcgcaa acgtacctgc
    12061 cagtatgcct ttgataacat tcttttgaac cgccatgatg cgactccttt ttttctcagg
    12121 gcatactctt aagattcatt ctttgcccgg aagtttcttc catgcgacgt tgttacgtaa
    12181 ataaaccggt tcggcatgtt ccaccgccac cgttttaccc tcggcaaaca tctgacacgc
    12241 aatcggcagc atatcttccg ccgctggcag taaaacttct ccgtcgcgca aaaccagccc
    12301 gctctcttta ccgagatccg gccaggcttg ccagcccgtc cctaccgtta cccattcgcc
    12361 ggaaagctgt tgcattcgtt catgaacgag ttcgggtttg agtacggctt cggtttcttc
    12421 accgtgccag ataccgtttt catcacgctg atattcggcc cagtaaactt cgcccattcg
    12481 cgcgtcaatg gctgccagca cgcgggttgc gccgtttttg cgccacgccc cttgcgccat
    12541 cgtcattagc gtggagacgc caatcatcgg tagctctgcg ccaagtgcca gcccttgcgc
    12601 aatgccaata ccaatgcgca cgccggtaaa gctaccgggg ccgcgcccgt aagccagagc
    12661 gttaatatca gtcagggaag ttccgctggt ggtcaggata tcctgcacca tcggtaagat
    12721 tcgttgagta tgttcacgag ggcaaagctc aaaatgagcg ttgacagtac cgtcgttcca
    12781 cagggcgaca gagcaggcct ctgtcgcggt atcgatagcc agaattcgca tgggtcttcg
    12841 tgcttagatc aataaaaagg cgcgcatcat accatactcc gtaacaaatt acctggagga
    12901 tggtatcgca aggaaacgaa ccgcacgggc aatgtcacga gtgcgtggcg cgggcggcag
    12961 actggcgaga aacgtcgcgc cgtaaggacg catcaccagc cgattgtcac aaatcaccag
    13021 cacgccacga tcgtcggcgt cgcgaatcag tcgccctacc ccctgtttga gagtaatgac
    13081 ggcatctggt agttgcactt catcgaacgg gtcgccaccg cgcaaacgac aatcttccat
    13141 gcgcgctttt aacagtggat catccggcga ggtaaacggc aacttgtcga taatcaccaa
    13201 tgacaatgta tcgccacgca cgtccacccc ttcccagaaa ctactggttg ccacaagaag
    13261 cgcgttaccg gcgctgacaa attgctgcaa cagttgccct ttgctggttt ccccctgcaa
    13321 caaaacggga agcgtcatgg tagcgcggaa ctgctcggcc agatcacgca tcatggcgtg
    13381 cgaggtacaa agcataaaac aacgaccgtt gttagcttcg atgatcggtc gcagcattgc
    13441 cgctaactgg cgagcagaac ctggctggtt ggtttgcggc agattgcgcg gcacacagag
    13501 taacgcctgg cggctgtaat caaacgggct tggcaatagc aacgactccg cctgttctat
    13561 cccaagccgc gaggtgaaat gatgcagatc gtcgttcacc gacagcgttg ctgaggtgaa
    13621 gatccagcta ccaggctttt gcgccattaa ctctttgaat ttatccgcca cgctgagcgg
    13681 cgtgagagcc agagtaaaat ggcgcgaagt gcattcgtac cagtagctgt agcccggctg
    13741 attgatctct tttagccgct tcagccgtgt gcgatacaac gtagcgcgct caaatgccgc
    13801 atccagcaag gcggaacgcc ccagtgacag tttcgccacg tcataacaaa gttccagggt
    13861 gtcatcgagc agtaaaaatg cccgctgaat ttgcggatta gctaacagct cacgcaggtt
    13921 accgcgataa cctggctcac cgagttgcag acgaaaatcc tgcgcactct gggcaagacg
    13981 atcagcgcac ttttgtaact gctgggtgtc ttttaattcg gtgcggtaag cgatggtgat
    14041 gtcttttgcc aggtcgagca gttgtcgact ggagagtgac tgaccaaaat actggctggc
    14101 aatgtccggt agctggtggg cttcgtcgaa gatcatgacg tccgcttccg ggatcaactc
    14161 gccaaatcca ctctctttaa ccaccatatc cgccagaaag agatgatggt ttaccaccac
    14221 cacatcggcg tccatcgctt ttttacgtgc tttgaccaca aagcaatctt tatacatcgg
    14281 gcagtcgctg ccaagacagt tgtcgttggt gctggtaacc agcggccacg cctgtgaatc
    14341 ttccgccacg ctgacgcagg tgctgatatc accatcgact gtttgattag accaggagcg
    14401 cagcaggatc acatcgctta agatttgtac cggcagatcg ccccccgcca gcgcctgctg
    14461 ttcgagacgt tcgaggcaga ggtagtttga gcgccctttc agcagcgcca cgttgcccgt
    14521 atatttcaat gcctttgaga ctgttggcaa atcgcggctg tggagctgat cctgcaacgc
    14581 ttttgagccg gtcgagataa tgactttctt tttcgcccgc agcgcaggag ccaggtaagc
    14641 gtaggttttg cccgtaccgg ttcctgcttc caccaccagc ggctggcctt tttctatcgc
    14701 ctgggtgacg gctaccgcca tctgtcgctg tggttctcgc ggcttaaagc ctggtatcgc
    14761 tttcgccagc tgaccgtctg gtgcaaaatc gtccgtcaca ctaccccctg ttgatttgaa
    14821 cagggattat gtcaggatga gggcgctttc gccagttgaa gtggtgacgg caacctcaca
    14881 ttgtggcagt ctttgcagca cgaaaatgga agtataatga ggacaaaatg atgactatcg
    14941 ttcgtatcga tgctgaagcc cgctggtctg atgtagtaat ccacaacaac acgctctact
    15001 acactggtgt accggaaaac ctcgacgccg atgcttttga gcaaaccgcc aacacgctgg
    15061 cgcagattga cgccgtgctg gaaaaacagg gcagcaataa atcgagcatt ctggatgcca
    15121 ccattttcct ggctgataaa aacgacttcg cggcgatgaa taaagcgtgg gatgcctggg
    15181 ttgtggcggg tcatgcgccg gtgcgctgca cggtgcaagc ggggctgatg aacccgaagt
    15241 ataaagttga aattaagatt gtggctgcgg tgtaagcttt atcgaagcaa aataagtcag
    15301 acgataattt atcgataata ctggtcggtt ttacataaat cgaccagaga ttaagatatt
    15361 actgttgatg ctcctgctaa ttcattattt atttttataa tttcaatttt agctataaag
    15421 ttaactatat aaataaacat aaccatgccg ttgtgttcgc cctctgacta gcaactctgg
    15481 ttttctttct tagctgaata atctggttat agcgtgagga ctgaccgtta aatttctcca
    15541 tcttactgga taacacacca tgagctgcta cctttaaaac acctgaatgt caacaggtta
    15601 actcgtgcca tatcgttata atccctttga tattagatgc aaattaaggt catatatagt
    15661 cttatcgata acatggttaa ttttaaggat aagaatatgc ctgctgtaat agataaagcc
    15721 ctggatttca ttggtgccat ggatgtatca gcgccaacac caagttcgat gaatgaaagc
    15781 acggcgaagg gaatctttaa atatttaaaa gaactgggag tacccgcgag tgccgctgat
    15841 attacggcgc gagctgacca ggaaggctgg aaccctgggt tcacggaaaa aatggttgga
    15901 tgggcaaaaa aaatggagac aggtgaacgc tctgtgatta aaaatcctga atacttttca
    15961 acatatatgc aggaagaact aaaagcactg gtctgagtta aatttatatc agcataaatg
    16021 ggtcaggacg cttttaatca catataaaaa gcgtcctttt tctcacaatc aaatgatcat
    16081 cggcttctat aacgaaatcg atacggatta gtgtgttact cgtcttcatc ctcaaaacgc
    16141 gccacgattc gctcgccgga gtggttggca cgcagctctt ctgccaccag cgcgattgcc
    16201 tggccgctgc tcatcccttg tgccatcagt tcctggatcc gctcgacagc tttttgctgc
    16261 tgttcatggg tgagtgaagg taaacctgca aacattgtta actcctgcta aattgttggc
    16321 gctaattatt tcatgctacc cggcacatag ccagtagagt caggactgat gaagacgtta
    16381 tctcccgctg tgattacttt accctggcgt caggacgccg ctgaatttta tttctcccgc
    16441 ttaagccacc tgccgtgggc gatgctttta cactccggct atgccgatca tccgtatagc
    16501 cgctttgata ttgtggtcgc cgatccgatt tgcactttaa ccactttcgg taaagaaacc
    16561 gttgttagtg aaagcgaaaa acgcacaacg accactgatg acccgctaca ggtgctccag
    16621 caggtgctgg atcgcgcaga cattcgccca acgcataacg aagatttgcc atttcagggc
    16681 ggcgcactgg ggttgtttgg ctacgatctg ggccgccgtt ttgagtcact gccagaaatt
    16741 gcggaacaag atatcgttct gccggatatg gcagtgggta tctacgattg ggcgctcatt
    16801 gtcgaccacc agcgtcatac agtttctttg ctgagtcata atgatgtcaa tgcccgtcgg
    16861 gcctggctgg aaagccagca attctcgccg caggaagatt tcacgctcac ttccgactgg
    16921 caatccaata tgacccgcga gcagtacggc gaaaaatttc gccaggtaca ggaatatctg
    16981 cacagcggtg attgctatca ggtgaatctc gcccagcgtt ttcatgcgac ctattctggc
    17041 gatgaatggc aggcattcct tcagcttaat caggccaacc gcgcgccatt tagcgctttt
    17101 ttacgtcttg aacagggtgc aattttaagc ctttcgccag agcggtttat tctttgtgat
    17161 aatagtgaaa tccagacccg cccgattaaa ggcacgctac cacgcctgcc cgatcctcag
    17221 gaagatagca aacaagcaga aaaactggcg aactcagcga aagatcgtgc cgaaaatctg
    17281 atgattgtcg atttaatgcg taatgatatc ggtcgtgttg ccgtagccgg ttcggtaaaa
    17341 gtaccagagc tcttcgtggt ggaacccttc cctgccgtgc atcatctggt cagcactata
    17401 acggcgcgac taccagaaca gttacacgcc agcgatctgc tgcgcgcagc ttttcctggt
    17461 ggctcaataa ccggggctcc gaaagtacgg gctatggaaa ttatcgacga actggaaccg
    17521 cagcgacgta atgcctggtg cggcagcatt ggctatttga gcttttgcgg caacatggat
    17581 accagcatta ctatccgcac gctgactgcc attaacggac aaatatactg ctctgcgggc
    17641 ggtggaattg tcgccgatag ccaggaagaa gcggaatatc aggaaacttt tgataaagtt
    17701 aataagatat tacgccaact ggagaagtaa gacgtggaat accgtagcct gacgcttgat
    17761 gattttttat ctcgctttca acttttgcgc ccgcaaatta accgggaaac cctaaatcat
    17821 cgtcaggctg ccgtgttaat ccccatcgtc cgtcgaccgc aaccggggtt gttgctgact
    17881 cagcgttcaa ttcatctgcg taaacacgct ggacaagtgg cattccctgg aggtgcagtc
    17941 gatgacacgg acgcatcagt tatcgccgcc gcgctgcgcg aagctgaaga agaggtcgct
    18001 ataccgcctt ccgccgttga agttatcggc gtgctgccgc ccgtcgatag cgtaactggc
    18061 tatcaggtaa ccccagtggt cggcattatc ccgcccgatc tgccgtatcg cgccagtgaa
    18121 gatgaagtct cggcggtgtt tgaaatgccg ctcgcccagg cattacatct gggtcgttat
    18181 caccctttag atatctaccg ccgtggcgat tcacatcggg tatggctgtc ctggtacgaa
    18241 cagtattttg tatggggaat gaccgcaggc ataattcgtg agctggcgct gcaaattggt
    18301 gtgaaaccct gactatactt atctttacat ctacaaaaca ctacttgaga caatcatcgc
    18361 aatattagtt aaatcgcggt ttttgattag tttaattcat gtgaatagtt aagccagtcg
    18421 ccgcgttccc tcttacacta tgcgctgtta ttagttcgtt actggaagtc cagtcacctt
    18481 gtcaggagta ttatcgtgat tagtctattc gacatgttta aggtggggat tggtccctca
    18541 tcttcccata ccgtagggcc tatgaaggcg ggtaaacagt tcgtcgatga tctggtcgaa
    18601 aaaggcttac tggatagcgt tactcgcgtt gccgtggacg tttatggttc actgtcgctg
    18661 acgggtaaag gccaccacac cgatatcgcc attattatgg gtcttgcagg taacgaacct
    18721 gccaccgtgg atatcgacag tattcccggt tttattcgcg acgtagaaga gcgcgaacgt
    18781 ctgctgctgg cacagggacg gcatgaagtg gatttcccgc gcgacaacgg gatgcgtttt
    18841 cataacggca acctgccgct gcatgaaaac ggtatgcaaa tccacgccta taacggcgat
    18901 gaagtcgtct acagcaaaac ttattattcc atcggcggcg gttttatcgt cgatgaagaa
    18961 cactttggtc aggatgctgc caacgaagtg agcgtgccgt atccgctcaa atctgccacc
    19021 gaactgctcg cgtactgtaa tgaaaccggc tattcgctgt ctggtctcgc tatgcagaac
    19081 gaactggcgc tgcacagcaa gaaagagatc gacgagtatt tcgcgcatgt ctggcaaacc
    19141 atgcaggcat gtatcgatcg cgggatgaac accgaaggtg tactgccagg cccgctgcgc
    19201 gtgccacgtc gtgcgtctgc cctgcgccgg atgttagttt ccagcgataa actgtctaac
    19261 gatccgatga atgtcattga ctgggtaaac atgtttgcgc tggcagttaa cgaagaaaac
    19321 gccgccggtg gtcgtgtggt aactgcgcca accaacggtg cctgcggtat cgttccggca
    19381 gtgctggctt actatgacca ctttattgaa tcggtcagcc cggacatcta tacccgttac
    19441 tttatggcag cgggcgcgat tggtgcattg tataaaatga acgcctctat ttccggtgcg
    19501 gaagttggtt gccagggcga agtgggtgtt gcctgttcaa tggctgctgc gggtcttgca
    19561 gaactgctgg gcggtagccc ggaacaggtt tgcgtggcgg cggaaattgg catggaacac
    19621 aaccttggtt taacctgcga cccggttgca gggcaggttc aggtgccgtg cattgagcgt
    19681 aatgccattg cctctgtgaa ggcgattaac gccgcacgga tggctctgcg ccgcaccagt
    19741 gcaccgcgcg tctcgctgga taaggtcatc gaaacgatgt acgaaaccgg taaggacatg
    19801 aacgccaaat accgcgaaac ctcacgcggt ggtctggcaa tcaaagtcca gtgtgactaa
    19861 tacttcttac tcgcccatct gcaacggatg ggcgaattta tacccgcttt ctcgtctgct
    19921 gtaatattcc ccactacact tccactgttg cgtcaggcgt ttgtcgccat acgcttacag
    19981 ggtggcccgc atgcaaaaag cacaacggat cattaaaacc tatcgccgta atcgaatgat
    20041 tgtttgtacg atttgcgcac tcgttacgct cgcttcgacc ctgagcgtgc gatttatttc
    20101 acagcgtaac ttaaatcaac aacgggtagt acaattcgcc aatcacgctg tagaggaatt
    20161 agataaagta ctgcttcccc tacaggcagg tagcgaagtc ttgcttccgc tgattggtct
    20221 gccctgctct gtcgcccatt tgccattacg taaacaggcg gcaaaactcc aaactgtgcg
    20281 atccattggc ctggtgcaag acggcacact ttattgctcc agcatttttg gttatcgcaa
    20341 tgtgcccgtc gtggacattc tggctgaact tcctgcaccg caaccacttt tacgcctgac
    20401 gatcgaccgt gccctgatta aaggcagtcc ggttttgatt caatggacgc ctgcagcggg
    20461 cagtagcaat gctggggtca tggagatgat taacatcgac ttactgacgg caatgctcct
    20521 tgagccacaa ctgccgcaaa tcagtagcgc cagcctgacg gtggacaaac ggcatttgct
    20581 ctatggtaat gggctggtag attcccttcc gcaacctgaa gacaatgaaa actatcaggt
    20641 ttcttcgcaa cgctttcctt ttaccattaa cgttaatggt ccgggggcta cggcgctggc
    20701 atggcactat cttccaacac aattaccgct ggcggtgctg ctaagtttac tggtgggcta
    20761 cattgcctgg ctggcgaccg cttaccggat gagcttttcc cgcgaaatca atctgggcct
    20821 ggcgcaacat gagttcgaat tgttctgtca gcctttgctt aatgcgcgca gccagcaatg
    20881 tattggtgta gagattttgc tgcgctggaa caatccgcgt cagggctgga tttcaccgga
    20941 tgtgtttatt cctatcgcgg aagaacatca tttaattgtg ccactgaccc gctatgtgat
    21001 ggcagaaacc attcgtcagc gccatgtttt cccgatgagt agtcagtttc atgttggcat
    21061 taacgtcgca cccagccatt ttcgccgtgg tgtgctgata aaagatctca atcagtactg
    21121 gtttagcgct cacccgattc agcaactgat cctcgaaatc accgaacgcg atgccttact
    21181 ggatgttgat tatcggattg cccgcgagct acatcgtaaa aacgtcaaac tggcgattga
    21241 tgacttcggc accggcaaca gttcattttc ctggcttgaa acattacgtc ctgacgtgct
    21301 gaaaattgat aagtcattta ccgcagctat aggttctgac gcggttaact cgacggtgac
    21361 cgatatcatc atcgcgctgg ggcaaagact gaatattgaa ctggtggcgg agggcgtgga
    21421 aacgcaagaa caggcgaagt atttgcgccg tcatggcgtg catattttgc aagggtattt
    21481 gtacgcacag ccgatgccgc tacgtgattt tcccaaatgg ctggcgggca gccaaccgcc
    21541 gcccgcccgg cataatggac atatcacgcc cattatgccg ttacgttaac gcttactcat
    21601 cttcatcgtg cgccggttgc tctttaacaa tgcgaaccag atcaacacga taatcattgg
    21661 cttcaatgat ggtgatatgc agtggcccta catcaatcac atcgcccaca cggggaatgt
    21721 gaccatttgc cgagatcacc aggcccgcga ccgtcgcgat atcatcgtca tcggcaaggt
    21781 gctcaacatc aagcgcctgc tgcaaggcat gcaaatctgt accgcctttt accagccagc
    21841 cgtcaccatc ggtaatgatt tccggcgttt cgtcagcgtc cgggaattca cccgcaatgg
    21901 cttccagcac atccagcggc gtgaccaagc cttgtaccac accaaactcg ttggtcacga
    21961 taacaaagct cccgcgagcg cgacgcagca cgcccagcag gttgatcgga tcgagggttt
    22021 ccgggacgat aatcgccgga gacgccgaag caatcgccgc cacatcaacg ccctcttcca
    22081 gcgccaccag cagttcttta gcacgtacga ttccgatgat ttcatccagt tcaccgcgac
    22141 ataccgggaa caggctgtgc ggtgaggaga gcaactgctc gcggatttca tcgaccccga
    22201 gattagcgtc aacccagctt atttcaccgc gcggcgtcat gatcccgcgc agagaacgcg
    22261 acgccagcgt cagtacgccg ttaatcatgt aacgttcttc ttcggcaaat gcaccttccg
    22321 ggatcggcat cggcatcggg ttatcggcat cgtgctgaac attggcctga cgtttcccgc
    22381 ccatcaaacg caggatggca tcggcagtac gcgctcgcag cggcaaagtc gactggtgac
    22441 gaataaagtt gcgacgcgca atctggttaa acacttcgat gatgatcgag aagccaatcg
    22501 cggcatacag gtaacctttc ggaatgtgga aaccgaaacc ttctgccacc agactcagac
    22561 caatcattaa caggaagctc agacagagca ccaccaccgt ggggtgctgg ttaacgaatc
    22621 gcgtcagcgg tttggatgcc agcaacataa ccgccatcgc aatcactacc gccgccatca
    22681 tcaccggcag atggttaacc atccctactg cagtaattac cgcatccaac gagaagacgg
    22741 cgtcaaggat gacaatctgt gtgacgacca cccagaaact ggcgtagcct ttaccgtggc
    22801 cggaatcatg atcgcggttt tccagccgtt catgcagttc ggttgttgct ttgaacagca
    22861 agaatatccc cccgaacaac ataatcaggt cgcgtccgga gaaggagaaa tccatgacgg
    22921 taaatagcgg tttggtcagc gtgaccatcc atgaaatcag cgacagcagc cccagacgca
    22981 taatcagcgc cagtgataac cccagcaaac gcgctttatc gcgttgtttt ggcggcagtt
    23041 tgtcagcaag aatggcgatg aagaccaggt tatcgatacc cagcacaatt tcgagaacaa
    23101 caagcgtgag tagccccgcc caaattgagg ggtccattaa gaattccatg acaagctcct
    23161 gcttaaggaa tagctattcg acgccagaaa taatgcaggc gtaacgacaa aatgcaaacg
    23221 aaaggtgcgg catagagagc cagaaaggca ggcgttaaaa ggcctgatgc tgaaatgacg
    23281 tcggtgacga tccatactgc gggctactgc cctatactcc atggttgtta aacgggagtt
    23341 aaacatatca gagacgcctc tgatttggca aagatttacc ttcctttgca aacgaatgtg
    23401 acaaggatat tttacctttc gaaatttctg ctaatcgaaa gttaaattac ggatcttcat
    23461 cacataaaat aattttttcg atatctaaaa taaatcgcga aacgcagggg tttttggttg
    23521 tagcccttat ctgaatcgat tcgattgtgg acgacgattc aaaaatacat ctggcacgtt
    23581 gaggtgttaa cgataataaa ggaggtagca agtgaccatt gctattgtta taggcacaca
    23641 tggttgggct gcagagcagt tgcttaaaac ggcagaaatg ctgttaggcg agcaggaaaa
    23701 cgtcggctgg atcgatttcg ttccaggtga aaatgccgaa acgctgattg aaaagtacaa
    23761 cgctcagttg gcaaaactcg acaccactaa aggcgtgctg tttctcgttg atacatgggg
    23821 aggcagcccg ttcaatgctg ccagccgcat tgtcgtcgac aaagagcatt atgaagtcat
    23881 tgcaggcgtt aacattccaa tgctcgtgga aacgttaatg gcccgtgatg atgacccaag
    23941 ctttgatgaa ctggtggcac tggcagtaga aacaggccgt gaaggcgtga aagctctgaa
    24001 agccaaaccg gttgaaaaag ccgcgccagc acccgctgcc gcagcaccaa aagcggctcc
    24061 aactccggca aaaccaatgg ggccaaacga ctacatggtt attggccttg cgcgtatcga
    24121 cgaccgtctg attcacggtc aggtcgccac ccgctggacc aaagaaacca atgtctcccg
    24181 tattattgtt gttagtgatg aagtggctgc ggataccgtt cgtaagacac tgctcaccca
    24241 ggttgcacct ccgggcgtaa cagcacacgt agttgatgtt gccaaaatga ttcgcgtcta
    24301 caacaacccg aaatatgctg gcgaacgcgt aatgctgtta tttaccaacc caacagatgt
    24361 agagcgtctc gttgaaggcg gcgtgaaaat cacctctgtt aacgtcggtg gtatggcatt
    24421 ccgtcagggt aaaacccagg tgaataacgc ggtttcggtt gatgaaaaag atatcgaggc
    24481 gttcaagaaa ctgaatgcgc gcggtattga gctggaagtc cgtaaggttt ccaccgatcc
    24541 gaaactgaaa atgatggatc tgatcagcaa aatcgataag taacgtattg tgttgattat
    24601 cactcagttt tcacacttaa gtcttacgta aacaggagaa gtacaatgga gattaccact
    24661 cttcaaattg tgctggtatt tatcgtagcc tgtatcgcag gtatgggatc aatcctcgat
    24721 gaatttcagt ttcaccgtcc gctaatcgcg tgtaccctgg tgggtatcgt tcttggggat
    24781 atgaaaaccg gtattattat cggtggtacg ctggaaatga tcgcgctggg ctggatgaac
    24841 atcggtgctg cagttgcgcc tgacgccgct ctggcttcta tcatttctac cattctggtt
    24901 atcgcaggtc atcagagcat tggtgcaggt atcgcactgg caatccctct ggccgctgcg
    24961 ggccaggtac tgaccatcat cgttcgtact attaccgttg ctttccagca cgctgcggat
    25021 aaggctgctg ataacggcaa cctgacagcg atttcctgga tccacgtttc ttctctgttc
    25081 ctgcaagcaa tgcgtgtggc tattccggcc gtcatcgttg cgctgtctgt tggtaccagc
    25141 gaagtacaga acatgctgaa tgcgattccg gaagtggtga ccaatggtct gaatatcgcc
    25201 ggtggcatga tcgtggtggt tggttatgcg atggttatca acatgatgcg tgctggctac
    25261 ctgatgccgt tcttctacct cggcttcgta accgcagcat tcaccaactt taacctggtt
    25321 gctctgggtg tgattggtac tgttatggca gtgctctaca tccaacttag cccgaaatac
    25381 aaccgcgtag ccggtgcgcc tgctcaggca gctggtaaca acgatctcga taacgaactg
    25441 gactaacagg tgagcgaaat ggttgataca actcaaacta ccaccgagaa aaaactcact
    25501 caaagtgata ttcgtggcgt cttcctgcgt tctaacctct tccagggttc atggaacttc
    25561 gaacgtatgc aggcactggg tttctgcttc tctatggtac cggcaattcg tcgcctctac
    25621 cctgagaaca acgaagctcg taaacaagct attcgccgtc acctggagtt ctttaacacc
    25681 cagccgttcg tggctgcgcc gattctcggc gtaaccctgg cgctggaaga acagcgtgct
    25741 aatggcgcag agatcgacga cggtgctatc aacggtatca aagtcggttt gatggggccg
    25801 ctggctggtg taggcgaccc gatcttctgg ggaaccgtac gtcctgtatt tgcagcgctg
    25861 ggtgctggta tcgcgatgag cggcagcctg ttaggtccgc tgctgttctt catcctgttt
    25921 aacctggtgc gtctggcaac ccgttactac ggcgtagcgt atggttactc caaaggtatc
    25981 gatatcgtta aagatatggg tggtggcttc ctgcaaaaac tgacggaagg ggcgtctatc
    26041 ctcggcctgt ttgtcatggg ggcattggtt aacaagtgga cacatgtcaa catcccgctg
    26101 gttgtctctc gcattactga ccagacgggc aaagaacacg ttactactgt ccagactatt
    26161 ctggaccagt taatgccagg cctggtacca ctgctgctga cctttgcttg tatgtggcta
    26221 ctgcgcaaaa aagttaaccc gctgtggatc atcgttggct tcttcgtcat cggtatcgct
    26281 ggttacgctt gcggcctgct gggactgtaa gactgttgta cactaccggg gccttttggc
    26341 cccgtttttt tatctggagg attaatgaca atcacggacc tggtactgat tcttttcatc
    26401 gccgcactcc tggccttcgc gatctacgat cagttcatca tgccccgccg taacggcccc
    26461 accctgctgg caattccttt gctccggcgt ggtcgcatcg atagcgttat cttcgtcgga
    26521 ttgattgtca ttcttatcta taacaacgtc acgaatcatg gtgcgttaat aacgacatgg
    26581 ttattaagcg cactggctct gatgggtttt tatatattct ggatccgcgt tccgaagatc
    26641 atctttaaac aaaaaggttt tttcttcgcc aatgtctgga ttgaatatag ccgaatcaaa
    26701 gcgatgaact tgtcggaaga tggcgtgttg gtgatgcaat tagaacagcg tcggctgtta
    26761 atccgcgttc gaaatatcga cgatctggaa aaaatttata agcttctcgt ttcaactcaa
    26821 taagttatga atttagccaa agctatgttt agtgtatttt taataatcag acatagctta
    26881 ggctatatta cctcttccct tatttgttat ttattttaac gtttcattga tatataaatc
    26941 taaatgtaaa tcgttatcaa taaagcaatg aaataatata ttccaacagt tgttttatat
    27001 tctcaaaata tgttaaggtt gcgccctcat ttggggagta gccgatttcc agattccgga
    27061 aatgtacgtg tcaacatact cgttgcaaaa cgtggcacgt acggactgaa tactttcagt
    27121 caggcgagac catatgcaca tcaatcgcta tgcctgcatg aacgcgaaaa ccatcgcggc
    27181 ttgttgttca tgtatgcatg tttgctgggg gcgatgatgt gctttatgga taccccggtc
    27241 aggacattgt catgaatatc actgctactg ttcttcttgc gtttggtatg tcgatggatg
    27301 catttgctgc atcaatcggt aaaggtgcca ccctccataa accgaaattt tctgaagcat
    27361 tgcgaaccgg ccttattttt ggtgccgtcg aaaccctgac gccgctgatc ggctggggaa
    27421 tgggcatgtt agccagccgg tttgtccttg aatggaacca ctggattgcg tttgtgctgc
    27481 tgatattcct cggcgggcga atgattattg agggttttcg tggcgcagat gatgaagatg
    27541 aagagccgcg ccgtcggcac ggtttctggc tactggtaac caccgcgatt gccaccagcc
    27601 tggatgccat ggctgtgggt gttggtcttg ctttcctgca ggtcaacatt atcgcgaccg
    27661 cattggccat tggttgtgca accttgatta tgtcgacatt agggatgatg gttggtcgct
    27721 ttatcggctc aattattggg aaaaaagcgg aaattctcgg cgggctggtg ctgatcggca
    27781 tcggcgtcca gatcctctgg acgcacttcc acggttaata agaacgctgc cagaggtgaa
    27841 tattaaagtc cgtctggcag tcgaacactt cttttgctgc cagtgtttgc cagacttctg
    27901 gcttcgcacg ccaggcaaac ggcgtcatct gcaataatgc gacggcttca tcaccgcgaa
    27961 gacgcatcgg ataacacaac tcatcactct gctgtaatgt aaaaccttcc agttgttctg
    28021 catgaggtgc atgaagatgt acttcattgt aaatcagccc cttcagctcc atcaaatgtc
    28081 gcggtcccgg cgtggcagta atgacccagc cgccgggctt cactactcgt gctaattctt
    28141 ctgctttaca cggcgcgtaa atacgtatta tggcgtccat actggtatcg gaaaacggca
    28201 aacggtggct ggaagcgaca caaagagtga cctgcggata gcgtttcgcc gccgctttta
    28261 tcgctacctt cgagacatcc aggccaaacg tggtgatttc gggcaacaca tcggcaaatg
    28321 cgtgtgtgta atacccttca ccacagccaa tatccagcac cgccgtggcc ttttcatcaa
    28381 gccgttcccg cagttgggcg acaattgcat cacgcagcgg ctgataatgt ccggcatcta
    28441 agaatgcgcg gcgtgcttgt atcatttccg cgctgtcgcc cggatcacga gaccgtttat
    28501 gctgaacggg cagcagattg acataccctt ctttcgccat atcaaactga tgtcgctggg
    28561 gacagatata gctgtttttt tcacgcgaaa gaggctgatg gcaaagtgga caggaaaacg
    28621 acatgacaac tccggcagga tactaaaggc cgcaagtgta acgcgaatca cgcggcgggc
    28681 aaatatccga acgccaggag cgaagataaa gcatagtaaa aagcctcgca ttcgacgagg
    28741 ctttatagcg agattgaagc gtattcacac ttcagatcag tggattcgat cagatagctg
    28801 ttacgttaac agctgccgga cctttctggc cgtcctgaat ttcgaactca acgttctgac
    28861 cttcagccag agttttgaag ccattaccct ggatagcgga gaagtgtacg aacacatctt
    28921 tgctgccatc agccggagta atgaagccaa aacctttaga ctcgttgaac cacttaacct
    28981 gacctttaat ctttgccatt tgaaaaattc cttagattgt tttcttcgcc cgcaggcata
    29041 acatagataa aactgacaca ttactgcatg aggcaccaat ataaggctcg gcagagaagc
    29101 ggtattcaac gtcaacgtgt ttactcagga cttctttact gaaaatgcca cacataaaca
    29161 gaactgtacc tcgtttaacc cgaaatctgt tatcacatac aacgttaatt atggcaagcc
    29221 atttttaaac atgtctcgat cagacgcaca aatctcgata cgtcttccac tttttttgca
    29281 cacttatgca acggaatacg cgccgatata tcattgtgct taaccttgcc agttcaggca
    29341 gatacttaaa ctggcgtatt ttctaacata gttcaataag ttcagttgtt ccaggccagt
    29401 gggagaagtt attacatagt gcgtgcaata tcacattttt tgctatgcaa tgaataaaaa
    29461 gttatatcac tttttctcat aaaacagtca gttaacggct atcaattacc ctaaagagaa
    29521 gtcaatcccc aaagggattg aaaatttaaa ataagaaaaa ttgatgaatg agcaaaaaaa
    29581 tcaagagaga aacgtttcgc taataaataa taccacgctt aatcacaaat ccgatgtaaa
    29641 catcctaata aattaatgag gaaaatatct ttttctgata tcccgttacg caaataaata
    29701 atatgataat tatttgaagt cagaccagag ttttaatttg aagcagttgc accatggcag
    29761 tgcgtataat caggatgaat tgagtaaccc ttcaacgacg gggttactca agattgagga
    29821 aggattatcg ttcggcgacc agacgaataa tatcttcgtc ttcaaccgat ttttgactct
    29881 caacggtctt tttatctgct ttctcaggtt cgtttgcttc gcacaaacga cgtaacagtg
    29941 cattttgacg tttttgctga tccagcaacg cctcaagcag ttcaatctgt tcgttagtcc
    30001 gagaactggc acgattaata aaaaaccaca agatgagccc gataagaaga accaccaccg
    30061 atacaaccaa agacgcaatg ttcatcacgc ctgaatttac aacttcgttc atttcaccac
    30121 ctctgagtag aggcgctatt ctaccactgc tggagaggaa gaaaatctag tgctgaaaaa
    30181 atgatatcac cacgggataa actggttaat ggcacaaatt ccgctgaaaa attgtacatc
    30241 ctgatcgcac atcatgttga atacctgcgc ccaaagcagc aagcaagcca acaccacgac
    30301 aaccagaacg acccatcgaa actttttcac tccaatctcc gtttcaccta ccttatgtca
    30361 ttaaactagc atgcgttagt taaacagcgc ctaactatgt cgatattcgt gctttttcgg
    30421 aatgagtcgc ttgcttcagc gcatattgcc gctacgatta agcgaacata aaaagagaag
    30481 aggttgtaat gcgattcatc attcgcacag ttatgctgat agcactggta tggataggat
    30541 tattactcag cggatatggc gttttgattg gaagcaaaga gaatgccgca ggattaggtt
    30601 tgcaatgtac ctatctgact gccagaggca ccagcacggt acaatacttg cacactaaaa
    30661 gtggtttctt ggggataaca gattgcccac tattacgtaa aagcaatatc gtggtcgata
    30721 atggttaagg gtaataaata accagattct cactcatgag taaaatattc ttatagcaag
    30781 cgcgtttaat ataacgcacc ttcaacttta tttttctcat gctaaataaa gaacctgtct
    30841 gtttgatatt ccgacaggtt cttactctca tcagaacgga tagtcgtgat aacccatttg
    30901 ggcagaaatt ttgcgcgctg cggtatgcaa cattgcgaca tattcctgta aacgctcttc
    30961 agagaaacgc aacgtcggga aggagatgct caaaccggca atgaccacgc caaagcgatc
    31021 aaataccggt accgcaatgc atcgcagccc ttcttcctgc tcttcgttat cttcgccata
    31081 cccctgctcg cgcacctggt ccagaacggg taataacgct tctgtactgg tgatggtccg
    31141 ctcggtactg cgtttatact ccacgccctc aagaatttgc ttcacttcat cgagatcgcg
    31201 ccatgccagc agtaccttac caatcgcggt gctgtacagc ggattacgac gcccaatccg
    31261 tgaatacatg cgcaaattgt acatagagtc aattttgtgt atgtaaacaa tactgtcttc
    31321 gtccagtgcg ccgaggtgga tagtttcttt ggtcaggcgg gagatctcac gcatctggat
    31381 atctgcgcta cgaattaaat cgacgttttg taacgcgcga gcgcccagtt caaacaattt
    31441 cagggtcagg gaatatttct ccgactcccc ttcctgcgcc acataaccta aggttttcat
    31501 ggtctgtaaa aagcgataaa cggtgctttt tgacatcatg acgcgctgcg acagctcggt
    31561 tatccctatt tcgcgctctt cacccagcgc ctgcaaaatg ccaaaaactt ttagcacgga
    31621 agatacagaa tcaggctgtt tatccagatc tgcgttagcc atttatcacc tcattgcgag
    31681 tgttttataa aaatcagaac tgttttttat tataatttcg caccagggtg gtcgcaatcc
    31741 atcttttgcc ggttagttac aattctgcga catccaccgt gaatatcagt gctagaatca
    31801 tacccctgtt gattattcac caaagatata aaattcctat gccaaaagtt caggccgacg
    31861 gcctgccatt gccccagcga tacggtgcga tattaaccat tgtgattggc atttcgatgg
    31921 ctgtccttga cggcgcaatc gccaacgtcg ccctgccaac aatcgccacg gaccttcatg
    31981 ccacgccagc cagttccatc tgggtagtga acgcctatca aatcgccatt gtcatctccc
    32041 tgctctcgtt ttcgtttctg ggcgatatgt ttggctatcg acgtatttat aaatgcggtc
    32101 tggtcgtttt tctgttgtct tcactgttct gcgccctttc tgattcgctg caaatgctca
    32161 cccttgcgcg tgtcatacaa ggtttcggcg gtgcagcgtt gatgagcgtt aataccgcac
    32221 ttatccgcct gatctatcca caacgttttc tggggagagg gatgggcata aactcgttta
    32281 ttgttgccgt ctcttctgct gccgggccga caattgctgc agcaatcctc tccatcgcat
    32341 cctggaaatg gttattttta atcaacgtac cgttaggtat tatcgccctg cttctggcga
    32401 tgcgttttct gccacccaat ggttctcgcg ccagtaaacc ccgtttcgac ctgcccagcg
    32461 ccgtgatgaa cgcgttaacc ttcggcctgc ttatcactgc gttgagtggt ttcgctcagg
    32521 ggcaatcgct gacgttaatt gctgcggaac tggtggtaat ggttgttgtt ggtattttct
    32581 ttattcgccg ccagctttct cttcccgtac cgctgctacc ggtggattta ctgcgtatcc
    32641 cgctgttttc actttctatt tgcacatctg tttgctcttt ctgcgcacaa atgctggcaa
    32701 tggtttccct gcccttttac ctgcaaaccg tgctcgggcg tagtgaagtc gaaacaggtt
    32761 tacttctgac accgtggccg ttagcaacga tggtgatggc tccgctggca ggctatttga
    32821 ttgaacgcgt acatgcagga ttgctgggtg ctttagggtt gttcatcatg gctgcggggc
    32881 ttttttccct ggttctgctg cccgcgtcac ctgcggatat caatattatc tggccgatga
    32941 tcttatgtgg cgctggattt ggcttattcc agtcacccaa taaccacacc attattacct
    33001 ccgctccgcg cgaacgtagc ggtggggcca gtggcatgtt aggaacggct cgtctactgg
    33061 gtcagagtag tggcgcggcg ctggtggcgc tgatgctaaa tcagttcggt gataatggta
    33121 cgcacgtttc gctgatggct gcggctattc tggcagtgat tgctgcctgt gtgagtggtt
    33181 tacgtatcac tcagccacga tccagggcat aaaaaaagcg cgtcgatcag gacgcgcttt
    33241 ttagtattta cttcatatta cttcaggtat tcacccgtac gcagagcttc aattcgttta
    33301 tccagcggcg ggtgagtcat gaacaactca ctgagcgatt tcgacttacc gttaatgcag
    33361 aaagccatca tgctggttgc ttcttgcggt tcatagctgg ttttcaggcg ctgcagcgcg
    33421 gcaatcattt tctcgcgacc aaccagtttt gccgaaccgg catcagcatg gaattcacga
    33481 tgacgcgaga accacatggt gataatgctc gcaagaatac caaacaccag ttccagaacc
    33541 gttgcaaccg caaagtagat cagcgggttg ccgttgctct cttcaccttc atcacgattt
    33601 ccgcccataa aacccgcggc aagctgcgcc agaatacggg aaataaagat aacgaaggtg
    33661 ttcaccacgc cctgaatcag cgtcatggtg accatatcac cattggcgat gtggctgatt
    33721 tcgtgagcaa ttaccgcctc ggcttcatcc gggctcatgt tctgcagcaa accggtgctg
    33781 acagcaacca gagaggcatc acggcgcgca ccggttgcaa aagcgttgat gtccggcgca
    33841 tggtagatag ccacttgcgg catagcgatc cctgcctgac gagcctgggt tgctacagta
    33901 ttaaccagcc aacgttccct ttcgttacgc ggttgctcga tcacttcccc gccaacagat
    33961 cgtaatgcca tccatttgga catcagaagc gaaacgaagg aaccaccaaa accgaacagc
    34021 aaggccatga tcatcagccc ctgaacgctg ctcgactgta tccctgtcag gctcagtacc
    34081 agcccgaaaa cgaccattac ggccaggttc gttagcagga agagcgcgat tcgcatcata
    34141 attttctttt tacctcagtt taacaaaacg caatatgcga tacccacatc gtatgggtta
    34201 cgcgactatt ttcaagtctg gatagtgcgt aagtcaccag aaagacacaa ctttacattt
    34261 tgtagcatct gatttacggc atcttgccgc tgttaaaaat caggcacaat ttcttgtgcc
    34321 tgattgatat tacttgacgg gagcgggttg ttccgcgggt ctggcttttt caagcttcgc
    34381 cagatcgagt gcgatattca ccgtctcatc cagataagga tccggctcct ggtaatcttt
    34441 aggtagatca tccagcttct tcaactccgg tttaccttcg cgtttaaagc gttcgttcaa
    34501 acgcgccaga cgcgtcgcat catcttcatt attctctttc tcacgcacag cgtagttcag
    34561 agaaacgata ttgcgcttgt ccttcatagc gttgaagcgc gcgatatcct tcatgatgtt
    34621 ctggaactca ggatctttcg cgatacgcgc attatgttcc ttcagcagct ccggcccaaa
    34681 ggccgttaaa tcgcctgatt tcacataagt cgcggcatca atgctatccc acggcagcgc
    34741 gttatcttcg aatttctcac ccgtttccgt ttcttcatta cccgtcggca tgatgatgtc
    34801 tggcgttacg cctttacgtt gcgtactgcc gccgttaacg cgatagaatt tctggatcgt
    34861 gtactgcaca gaacccagcg ctggccattc aggacgtaac atctgatcgt aaatacggtt
    34921 caatgaacgg tattgctgaa cggtgccttt accaaacgtc ggttcaccca caaccagcgc
    34981 acgaccgtaa tcctgcattg ccgcggcaaa gatttctgaa gccgaagcac tgaaacggtc
    35041 aaccagtacc accagcgggc ctttatagaa cacctgcccg tcggtatcgc tgtcttcacg
    35101 aaccttgccg ttgttatcgc ggacctgaac aatgggaccc gcaggaataa acagacctga
    35161 gagcgatacc gcttcggtca gcgccccacc gccattgcta cgcaggtcga tgatcacact
    35221 gctgacattc tgtttttcca gtttctgcag ttgaactttg acatcgtctg tcaaacccac
    35281 atagaagccc ggaatatcca gcacgccgac tttctcttta ccgacggtct tcaccgacat
    35341 tttaaccgcg cggtcttcga gacgaatacg ttcacgggtc aatgttacag tgcgggtctt
    35401 ggtcccttta ccagcaggta aaatttccag acgaacttta ctgcccttcg gccctttaat
    35461 taaggcaacc acatcatcaa gacgccagcc aatcacgtca accatcggct tgcctgtttg
    35521 accaacaccg acaattttgt caccaacgct gatagcttta ctcttcgctg ccggaccacc
    35581 tgccaccatc gaattgataa cggtgtagtc atcatccatt tgcagcactg cgccaatacc
    35641 ttccagcgac aaactcattt cagtgttgaa ctgttcggta ttacgcgggg aaagatagtt
    35701 ggtatgcggg tcgatttcac gcgcaaacgc cgtcattgcc agcgagaaaa catcttcgct
    35761 gttggtttgc gccagacgac gaatggcaaa tttgtagcgg cgtgtcaggg tttcacgaat
    35821 ttctttatcc gtttttcctg ccagcttcag gcttaactcg tcgaatttga ctttactgtc
    35881 ccacagcgcg ttcaactcag cctcgttttt cggccagggc gctttgctgc ggtcaaggtt
    35941 ataagtgtcg ttgccggtga aatccatcgg cttttccagt accgacaaag cgtactggta
    36001 acgctcaaaa cggcgctttt gcgccagatt gtagagatcg tagaaaacgt cgagtttgcc
    36061 tgaacgcagt tcatcgccta actcggtttt ctttttcgcg aactgttcaa catcgcttgc
    36121 cagcagcacg ttgtggctgt aatcgagcag attcaggtag cggtcaaaga ttttggccga
    36181 aaatgcctga tcgaggtcga actggcgata atgagaacgg gtgaagcgcg acgttacgcg
    36241 ctcacttacc gtcgcatgct gcgtctcttc ctttaatacc ggaatttgat cagcacgcgt
    36301 gatatcttct acagcgaagg tctggcctgc tattgcaagc aggccagcta acgcggtaag
    36361 cctaaaaaac atgttcatgc ctggcccggc ctccgtttca gaacaccagg tgttctgcgc
    36421 gcacaatcaa agacataccc gaattcagct ggacgcggac gccgtctttg gtgatttcta
    36481 atacggtggc atccatcgcg ttttgacccg ctttcacctt cagggcttgt ccgacagtca
    36541 gagctgaaat gtcagaaacc ggggtgtgct gttcttcgcg aggtgctttt actgtttttg
    36601 gcgctttctc taccggcttt tgcgcacgag gtttacgttc agcgccttct ttgcggcgtg
    36661 gcgtggtcgg acgtggcttg cgttcgcggc gcggtgcgtc ttctttctca ccagcagctg
    36721 cggcagcttc gcgttttttc gcttgctgtt cagcacgctg tgcctgaaca cgcgctttcg
    36781 cttcttcaag ctgcttgcga gcatgctcta catgttgctc gtccagctca ccgcatgggt
    36841 tgccgtcaag atcgacacgc gttgcgccgg gtttaacacc gtaaagataa cgccagctcg
    36901 aagtgtagag acgtaaagcg gatcgtaatt gcgttttgct caggttcatt tccccggcaa
    36961 cacgatcgac caaatcctga aaaataccga ttttcagcgg acgcgcttca ccttccgcac
    37021 tgaaacagtg gggaaaacgt tcggccagaa acgcgattac ttctttactg ctattcaact
    37081 taggttgatt ttccatgaaa tttcctgatt acaacggacg tagccaacaa gcgcaggcat
    37141 gaacaggcgt cattataatg acgctaccag taaatgctac gttatccgtt gattatcctg
    37201 cgacgctcgc aaagaatttt ttgtaatccg tcgttgcaag cactttttca agctgtgcca
    37261 caagctgacg taagccttgc tcgtcctcgt ctgtaaagcg accgaagacg gtactatcga
    37321 tgtcaagaac accaataatc tgatttttca ccaccagcgg cagaacaatt tcagaattac
    37381 tcgccgcatc acaggcaata tgcccgtcaa acgcgtgaac atcctcgata cgctgcactt
    37441 gattgcgggc aaccgcagtg ccgcacaccc cgcgcccgac gggtatccgg acacaggcaa
    37501 ttttgccctg aaatggtcct agtaccagtg tatcgtcctc aagcaaataa aaacctgccc
    37561 agtttacgtc agtgagacgc tcgtataaca acgcactggt gttcgcaagc gttgccagaa
    37621 aactggtttc tcccgccatc agcgcgttaa agtcgcgatt taaatccgcg taaaattctg
    37681 ttttgttcat tatataatca cttggttgtc ttacctggaa ctgccagcct attaaaataa
    37741 gcattaaatg cgttaatgct caagatcatt ccaatcatgg gttaatatta atgttaattc
    37801 ttattacatt tggcacgtca tggctcttaa cacaccacaa attacgccga caaaaaagat
    37861 aacagtgagg gcaatcggcg aggaactgcc gcgtggtgat taccaacgtt gcccgcaatg
    37921 tgacatgctg tttagcctgc ccgagataaa ttctcatcag agtgcctatt gtccgcgctg
    37981 tcaggcaaaa attcgcgacg ggcgcgactg gtcgctaacg cgcctggcgg caatggcttt
    38041 caccatgctg ttgctgatgc cgtttgcctg gggcgaaccg ctgttgcata tctggctgtt
    38101 aggtattcgt atcgacgcca acgtcatgca aggcatctgg caaatgacca aacagggcga
    38161 tacgataacg ggggcgatgg tctttttctg cgttattggt gcccccctca ttctggtgtc
    38221 ctccatagca tatttatggt ttggtaaccg actgggaatg aatttacgtc cggtactgct
    38281 gatgcttgag cgacttaaag agtgggtaat gctggatatc tacctggtcg gcattggcgt
    38341 tgcttctata aaggtacagg attatgccca tatccaggcg ggtgtcggct tgttctcttt
    38401 tgtggcgttg gtgattttaa cgacggtgac gttgtcacat cttaatgtcg aggagctgtg
    38461 ggagcgattt tatccgcagc gccccgctac gcgtagggac gagaaacttc gtgtctgtct
    38521 tgggtgccat tttaccggct atcctgatca gcgtggtcgc tgcccgcgtt gccatatccc
    38581 gctacgcctg cgtcgccgtc atagtttgca aaaatgctgg gcggcgctgt tagcgtcaat
    38641 cgttttgttg ttacctgcca acctgttgcc tatttctatc atttatctga acggaggacg
    38701 gcaggaagat acaattcttt ccggaattat gtcgctggca agtagcaaca ttgcggttgc
    38761 gggaatcgtg tttatcgcca gtattctggt accgtttact aaagtgatcg tcatgttcac
    38821 tttactgttg agcattcatt ttaaatgcca gcaaggttta cgcacacgca ttctgttact
    38881 gcggatggtg acctggattg gtcgctggtc gatgctcgac ctgtttgtca tatctttaac
    38941 catgtcgctg attaatcgcg atcagatcct cgcttttact atgggaccgg ctgcgtttta
    39001 tttcggcgca gcggtaattt tgactattct tgctgtggaa tggctggaca gccgcttact
    39061 ttgggatgca catgagtcag gaaacgcccg cttcgacgac tgaagcgcag attaaaaata
    39121 aacgccgtat ctcacctttc tggctgctgc cgttcatcgc gctaatgatt gccggttggc
    39181 tgatttggga cagttatcag gaccggggta ataccgtcac catcgacttt atgtcggcgg
    39241 atggtattgt cccgggccgt acgcctgttc gttatcaggg cgttgaagtc ggaacagtgc
    39301 aggatatcag cctcagcgac gatcttcgta agattgaagt caaggtcagc atcaagtccg
    39361 atatgaaaga tgcgctgcgc gaagagactc agttctggct ggtgacgcca aaagcatcgt
    39421 tggcaggtgt ctccgggctg gacgccctcg tcggtggtaa ctatatcggc atgatgccag
    39481 gtaaaggtaa agagcaggat cactttgtcg cactcgatac ccaaccgaaa tatcgactgg
    39541 acaatggcga tctgatgatc cacctgcaag cccccgatct cggttcgctg aacagcggtt
    39601 cattggtcta tttccgcaag atccctgtgg gaaaagtcta cgactatgcc atcaatccca
    39661 acaagcaagg cgtggtgatt gatgtcctga tcgagcggcg ttttaccgat ctggtgaaaa
    39721 aaggtagccg tttctggaac gtttccggcg ttgatgccaa tgtcagtatc agtggcgcga
    39781 aggtgaaact ggaaagtctg gcggcactgg ttaacggtgc gattgccttc gattcacctg
    39841 aagagtcgaa acctgccgag gcggaagata cctttggtct gtatgaagat ctggcccaca
    39901 gccagcgtgg cgtaataata aaactggaac tgccgagtgg ggcaggatta accgccgact
    39961 cgacgccatt aatgtatcag ggactggaag tcggacagct aactaaactg gatttaaatc
    40021 ctggtggtaa agtcactggg gaaatgacag ttgatcccag cgtcgttacc ctgcttcgtg
    40081 aaaatacccg catcgaatta cgtaatccga aattatccct tagcgatgcc aatctcagcg
    40141 ccctgctgac tggcaaaacc ttcgagttgg tacccggcga tggcgagcca cgcaaagagt
    40201 tcgttgttgt gccaggcgaa aaagcactgc tgcatgaacc tgatgttctg acgctgaccc
    40261 tgaccgcgcc ggaaagttac ggtattgatg ctggtcagcc gctcattctt cacggcgtgc
    40321 aggtaggcca ggttatcgat cgtaaactca ccagcaaagg cgtcaccttt accgtcgcca
    40381 tcgagcctca gcatcgagaa ctggtaaaag gcgatagcaa atttgtcgtc aacagccgtg
    40441 tcgacgtgaa ggtggggctg gatggcgttg agtttctcgg tgccagcgcc tcagaatgga
    40501 ttaacggcgg gatacgtatt ctgccgggcg ataaaggcga gatgaaagcc agctatccac
    40561 tgtatgccaa tctggaaaaa gcgctggaga acagccttag cgatttaccc accacaaccg
    40621 tgagtttgag tgcagagacg ctgccggatg tgcaggcagg atcggtagtg ctctaccgta
    40681 aatttgaagt tggtgaagtt attaccgtgc gtccgcgagc taacgcgttt gatatcgatc
    40741 tgcatattaa gccggagtat cgcaaccttc tgaccagcaa tagcgtgttc tgggcagaag
    40801 gcggggcgaa agttcagctg aatggtagtg gcctgaccgt acagacatcc ccgctctcca
    40861 gagcattaaa aggggctatt agcttcgata acctcagtgg tgccagcgcc agtcagcgta
    40921 aaggcgacaa acgtattctg tatgcttccg aaacagcggc ccgtgcggtt ggtgggcaga
    40981 ttacgcttca cgctttcgat gccggaaaac tggcggtcgg gatgccaatt cgctatctcg
    41041 gtattgatat cgggcaaatc cagacgctgg atctgattac cgcgcgcaat gaagtacagg
    41101 caaaggcggt gctctatccg gaatatgtcc agacctttgc tcgcggtggt acgcgcttct
    41161 cagtggtcac accgcaaatt tcggcagctg gcgttgagca tcttgatact atcctccagc
    41221 cgtatatcaa cgtcgaacca ggccggggca atcctcgccg cgactttgaa ttacaagagg
    41281 ccaccattac tgattcgcgt tacctggatg gcttaagcat tattgttgaa gcgccggaag
    41341 ccggttcgtt aggtattggt acgcctgtgc tgttccgtgg tctggaagtc ggtacggtta
    41401 caggaatgac gctggggaca ttgtcagatc gcgtgatgat tgcgatgcgc atcagtaaac
    41461 gctatcaaca cctggtgcgt aacaattccg tcttctggtt ggcatcgggt tacagtctgg
    41521 actttggtct gacgggcggc gtagtgaaaa ccggcacctt taaccagttt atccgtggcg
    41581 gcatcgcctt cgccacgcct ccaggtacgc cactggcacc gaaagcccag gaaggcaaac
    41641 acttcctgtt gcaggaaagt gaaccgaaag agtggcgtga atggggaact gcgcttccca
    41701 aataatgccc actgctccgg cgtgcctgcg ccggagcgtt tatgctaaac tgcgcgcctg
    41761 tttttttgcc agtggtacat gctcgtggcc caacacaccg tttatttccc ggacgccttt
    41821 ctgacacaaa tgcgcgaagc gatgccttcg acgctctcat ttgatgattt tcttgccgcc
    41881 tgtcagcgcc cgttgcgccg cagcattcgc gttaatacgc tgaaaatctc cgttgctgat
    41941 ttcctgcaat taaccgctcc ttatggctgg acgcttacgc caattccgtg gtgtgaagaa
    42001 ggtttctgga ttgaacgcga caatgaagat gcattgccat tgggtagtac cgccgagcat
    42061 ttaagcggcc tgttttatat tcaggaagcc agttcaatgt tgcccgttgc cgccttgttt
    42121 gctgacgata atgcaccaca gcgggtgatg gatgtcgcag ctgcgccagg ctccaaaacg
    42181 acgcaaattg ccgcgcggat gaataacgaa ggggcaatcc ttgccaatga gttttccgcc
    42241 agtcgggtaa aagtgttaca tgccaatatc agccgctgtg gcatcagtaa tgttgcgctc
    42301 acacattttg atggccgcgt gtttggtgcg gcagtgccag aaatgttcga tgccattttg
    42361 ctggacgctc cctgctctgg cgaaggcgtg gtgcgtaaag atcccgatgc gctaaaaaac
    42421 tggtcaccag aaagcaatca ggaaatcgca gctacacaac gggagcttat cgacagcgcc
    42481 tttcatgcat tacgtcctgg tggtacgctg gtttactcga cctgtacctt aaaccaggaa
    42541 gaaaacgaag ccgtttgcct gtggctgaaa gagacttacc ccgacgcagt agagttttta
    42601 ccacttggcg atctcttccc tggtgcaaac aaagcgctga ccgaagaagg ctttttgcat
    42661 gttttcccac aaatttacga ctgcgaaggc ttcttcgttg ctcgtctgcg taaaactcag
    42721 gcgatccccg ccttacccgc ccccaaatac aaagtcggta atttcccgtt cagcccggtg
    42781 aaagatcgcg aagccggaca aattcgtcag gcggctgcaa gtgttggctt aaactgggat
    42841 ggaaacctgc gactctggca acgcgacaaa gaactgtggt tgttcccggt gggcattgaa
    42901 gccctgatcg gtaaagtccg attttctcgc ttggggatta aacttgccga aacgcacaac
    42961 aaaggttatc gctggcagca tgaagcagtt attgcccttg ccacccccga caatgtgaac
    43021 gcttttgaac tgacaccgca ggaagcggag gagtggtatc gcgggcgcga tgtttacccg
    43081 caagccgcgc cagtggcgga tgacgtgttg gttactttcc agcatcaacc gattggttta
    43141 gccaaacgga ttggttcgcg attgaaaaac agctatccgc gtgaactggt gcgcgatggg
    43201 aaacttttta ccggtaacgc ctgacagcgc acaaaaaaag cgcacttttt gactggcaca
    43261 ttcggctgcc tcaactaggc tgaaaaatgg tgcgatcgga ctggtcgtac cacaaccggc
    43321 agctaaatgg agagcacgaa gatgaaaacc agtgtgcgca taggcgcttt tgaaatcgac
    43381 gacggcgaat tacacggtga atcgccgggt gatcgaacgt taaccattcc ttgtaaatct
    43441 gaccccgatt tatgtatgca actcgatgcc tgggatgctg aaaccagtat ccctgccctg
    43501 ctaaatggcg aacactctgt cctttaccgt acccgttacg atcaacaatc tgatgcctgg
    43561 attatgcgtc ttgcctgatc caaaaagaac ccgtcggcat ggcgggttat ttgtcctggt
    43621 tattcccccg ttgtaaaatc tctcctaaac ttaacggtac ggcaccacac ttcggggatg
    43681 aaatgttcgc gctggtactt tttgtttgct acctggatgg cggttgtgaa gatattgttg
    43741 tggatgtcta caacacggaa cagcagtgtc tttattctat gagcgatcaa cggatccgcc
    43801 atggcggttg ttttccgatt gaggatttta tagatggttt ctggcgacca gcacaggagt
    43861 atggtgattt ttaattattg caattgcaca agagtcagtt cgcccccaaa gacagcaccg
    43921 gtatcaatat aatgcaggtt gccaatatcc acgcgatgtc gcaacggtgt atgaccaaac
    43981 cagaaatgat cagcacctgt aattccctgc cctttttggc gttcacctaa tcgcgagcgg
    44041 ctccacaaga cctgatgcaa atcaacgtcc ttttgccatt cataaacatc atctggataa
    44101 tcggcatgag caataacatg tttgccggta cgactgtgta cttcaagaat aaagggcaaa
    44161 tgctgacatt tttccagcgc cgttttcgct tgtttctgtt gattatctgc cagcgcaata
    44221 aaccagtcgc cgccattcat caaccacaaa gacatctgct gggatgccag cgcatccatc
    44281 gccatctgtt catgattgcc tcttaccgca cgaacccaat gttgttccag taactgcagg
    44341 caacgtaaac tttgcggccc acgatcgata acgtctccca ctgagataag taaatctcgc
    44401 cacggatcaa aaccacaatg ccataatttg cggcgcaact gctcaagaca accgtgtata
    44461 tcgccagaaa gccagatatg tcgccattga tgacccgcaa ttctctgata aacgggcgca
    44521 ggctgtttca tcaatatttt cctcccgcgc taaagatcac ataatcttaa caagaatgtt
    44581 aaaaaacgct ggactcagac agtagagtgt gtgttatggt tgactataaa gtcagcgaag
    44641 gaaatgcttc tggcttttaa catataaaaa gagaccgaac acgattcctg tattcggtcc
    44701 agggaaatgg ctcttgggag agagccgtgc gctaaaagtt ggcattaatg caggcttagt
    44761 tgccttgccc tttaagaata gatgacgacg ccaggttttc cagtttgcgt gcaaaatggt
    44821 caataaaaag cgtggtggtc atcagctgaa atgttaaaaa ccgcccgttc tggtgaaaga
    44881 actgaggcgg tttttttatt ggaaatcaaa aggctatttt aggtaattaa cagagttttt
    44941 cagctcgttc tataaacggt gccagactca ttttttcgcc gggattgtta ggatcatcaa
    45001 tctgaatcac cgaaatgggt tgggctttag tcttcccact ggcaacttcc ttttgtgcga
    45061 tatcgtttaa aggatactgc acgagggtac ttgggttgat gacatacaaa gcattacccg
    45121 gtcggcaagt cagcatcacc tcttcgcgat taaacgccca tttgtcttta cccacttcaa
    45181 aacggctgac ggtaatcacc tgcggtgcag ccagcgccgc tgcagaactg gtgagtaaca
    45241 gaaacgccag aatacttttt ttcatcattt tcgtaatcca tcaaaaaggt tcgagagtcg
    45301 caagcaggct gatgatcacc agcactaccg cacctatcgc ccattcgagt ttagtcatcc
    45361 actcaaacca gggtgccgca cgatcttcat cctgcctcat gcgcggtaca agaacataac
    45421 gattagccag cgcaatgacc accataatca tcaccaggat ggctttgagc aataagagtt
    45481 ggccccagta agtcgtaagc gtggggggaa atccggtaat caacaatgca ttaagcacgc
    45541 cgcttgccag tacgccgatc accgcaaaat gcccgcacca ggaaaaacgc atcagcgcct
    45601 gaatggcctg gtgtcgccaa cggcctttga tgagttgcat acaccagagc accggcagta
    45661 atcccccaaa ccacgccgcc gcacaaatca ggtgaatcgc gtgattagtc tgatggattt
    45721 tcgccgttac cccttcattc agtgtcgcat gcccgattcc cgccagcaga ataaattgcg
    45781 cggtagtgag cataaacagc aaacgtggca tattccgcgg ttgcataagg gcgacgatca
    45841 acgttacgag ggcgagaaca atttgccata accagacgcc accaaactgc gtttgcaaaa
    45901 cagcctgcca aatgtttggc gaaaatacat ctgcccatcc cgttcccatc aacccgccct
    45961 gaacggcgag cattgcagtg gcactgatca aactccagac ggcagcgtgc tgttgtaaac
    46021 gcagaaaacg cttcgccagc aagcgacgaa tcgttaaggg ggccagccag gcaccgtaca
    46081 ttgcgaagcc aaagaccagc atcagcgagg tgaaatggat aaatcgcagc gcgatccagg
    46141 taaacgccag catgatttat ttcacgctaa aggtgtagtg tcctttcgtt ttatgcccgt
    46201 ccaccgaaac aacatgccag tcaacggtgt aggttccggg tttcagcgaa tcggccagtg
    46261 gaacaatcag ttgcttttgg tcctgctcat ttcgcttcgc cggtaatgtt ttaatatttt
    46321 cgttttttgg ccccgtgatt tttgcaccac tgaatcctgt ttcaacacct tccgagaagt
    46381 ttaaagtgat tgcctgcggt gcagctgtca cttgcgcgtt tgccgcagga tactgatgcg
    46441 ttaaatgcgc atgtgcccag acggaaggtg tcaccaacga agtggtcagg attgccagcg
    46501 cgtagcgaag ggagcgtgca gttgaagtca tattatctat tcctttttgt aataactttt
    46561 ttacagagca taaccttgtc taatgtctga gtcgaggatc atcaattccg gcttgccatc
    46621 ctggctcact cttagtaact tttgcccgcg aatgatgagg agattaagaa tgctgaagaa
    46681 tctggctaaa ctggatcaaa cagaaatgga taaagtgaat gtcgatttgg cggcggccgg
    46741 ggtggcattt aaagaacgct acaatatgcc ggtgatcgct gaagcggttg aacgtgaaca
    46801 gcctgaacat ttgcgcagct ggtttcgcga gcggcttatt gcccaccgtt tggcttcggt
    46861 caatctgtca cgtttacctt acgagcccaa acttaaataa aacttataca gagttacact
    46921 ttcttacata acgcctgcta aattatgagt attttctaaa ccgcacccat aatttgcagt
    46981 cattttgaaa aggaagtcat tatgtcgttc tggaaagttg cagcagcgca atatgagcct
    47041 cgtaaaacct cactcaccga acaggtagct catcatctgg agtttgtgag ggccgccgcc
    47101 aggcaacaat gtcagctgtt agtttttcca tcgctttctt tactggggtg tgattattcg
    47161 cgacgtgccc ttcctgcccc acccgatctc tcactgttag acccgctttg ttatgccgca
    47221 acgacctggc gaatgaccat cattgccggc cttcccgttg aatataacga tcgctttatt
    47281 cgtggaattg cggtgttcgc accgtggcga aaaacgcctg ggatctacca tcagagtcat
    47341 ggtgcatgtc tgggccgtcg ttccagaacc atcacggtgg tcgatgaaca accgcaaggt
    47401 atggatatgg acccgacctg ttcactgttt actacagggc aatgtctggg agaacccgac
    47461 ctgctggcgt cggcccgtcg cttacaattt ttttcacatc agtactcgat tgccgtgctg
    47521 atggcaaatg cccgtggtaa cagtgcacta tgggatgaat atggtcgtct catcgttcgc
    47581 gccgatcgtg gttcattatt gttagtcggt cagcgttcat cacagggttg gcaaggcgat
    47641 atcattccat tacgctaggc tttttcggcc tggagcatgc catgttgcgc attatcgata
    47701 cagaaacctg cggtttgcag ggagggatcg ttgagattgc ctctgttgat gtcattgacg
    47761 gaaaaatcgt caaccccatg agccacctgg tgcgccccga tcgtcctatt agtccacaag
    47821 cgatggcgat tcatcgcatc accgaagcca tggtcgccga taaaccgtgg attgaagatg
    47881 tgatcccaca ctattacggt agtgaatggt atgtcgcgca taacgccagc tttgaccgcc
    47941 gcgtactgcc tgagatgccc ggtgagtgga tttgcactat gaaactggcc cgtcgtttgt
    48001 ggcctgggat caagtacagc aatatggcgt tatataaaac acgcaagctc aatgtacaga
    48061 cgccgccggg cctgcatcat caccgcgcgt tgtatgactg ttatatcacc gccgcgttgc
    48121 ttatcgatat tatgaacacc tccggctgga cggcagaaca gatggccgat atcaccggac
    48181 gtccgtcgtt gatgacgacc ttcacctttg gcaaataccg tggcaaagcg gtttccgacg
    48241 ttgccgaacg cgatccgggc tatctgcgct ggttatttaa taacctggac agcatgagcc
    48301 cggagctgcg tttaacactg aaacattatc tggaaaatac ttagtccgca ggcgtagcgg
    48361 gtaatgttcc ctgcgccagc gcgaccagaa aagcatattc catcgctacg ccttcgtacg
    48421 atttaaagcg accagattta ccgccatggc ctgagtccat gtcggtacag agcaataaaa
    48481 gatggtcatc ggttttcagc tcgcgcaatt tagcgaccca ttttgccggt tcccaatatt
    48541 gcacctgaga atcgtgcaaa ccggtcgtta ccagtaaatg cggataagcc tgtgcggtga
    48601 cgttgtcata tgggctgtag cttttcatgt actcgtaata ttgcggatcc tgcggattcc
    48661 cccactcttc aaactcacca gtggtaagag gaattgattc atcaagcatc gttgttacaa
    48721 catcaacaaa cggtacctgg gcgataacgc cgtggaataa ttccgggcgt tgattaattg
    48781 caacgcccat caacatgccc cccgcactcc cgcccatcgc ataacaaagc gaaggagagc
    48841 catagcccag ttttaacaat gcatcgcagg catcaagata atcattaaac gtatttttct
    48901 tcttcagaaa ttttccgtct tcgtaccatt gttgccccag ctcaccaccg ccgcgaacat
    48961 ggacaatggc gtagacaaag ccacgatcta acaaactcaa gcggctaaaa ctgaaatcgg
    49021 catcaatact tgcgccgtaa gaaccatagc catacaccag caacgggttg tgtcctttgc
    49081 gaaaatgttt gcgatggtag accaacgaaa ccggaacttc gacgccatca cgggcgacta
    49141 tccacaggtg ttcactgcgg taattcgccg catcaaaacc gggcacttct gtttgtttta
    49201 atacacgacg ctcaccggta tccatatcca gttcaaacaa agtatctggt gtggtcatgg
    49261 aagaataacc ataacgcaat cgcgcggttt caggttctgg attgtaggca atccaggtca
    49321 cataggccgg atcatcaaag gcaataccaa tgacttcccg ggtcttgcgg ttaatttggc
    49381 gcaaactggt taacccgcgc tgacgctctt caaccaccag ccagtcggta aacagcgtaa
    49441 acccttccag cataatgtta tcgcgtggcg gaattaactc ttcccactgt tgctcatcac
    49501 gcaggcgggt acggtataag ccaaagtttt tgccatggcg gttggaacgc agataaaacc
    49561 gatgctggta gtgatcaagg ctgtattcgt gatctttgcg gcgcggcaga aaaacaaacg
    49621 gctcggcatc ggccatttcc gcgtccagca ggcgaacttc actggtggtg gcgctggcca
    49681 aatgaatgac tacatagtgc ttcgaggtcg ttttatgcag gctgacgtaa taggtatcgt
    49741 ctttttcttc gtagatcagt ttatcttgcg atgctggcgt accgatggcg tgacgccaga
    49801 cctgataagg cagcagcgtc accggatgct tgcgaacata gtagaaagtc caggagtcat
    49861 ttgcccagac aaagctgggt tcaacgttat ccagcagttc cgggtaccag ttaccagttt
    49921 ccagattacg aaaacgaatg ccgtactggc gtcgggaaag aaaatcttct gccagcgcca
    49981 taatggtgtt atcgggcgta atcgccattc cgcccatcga ataaaactca ctatgagctg
    50041 cgcgcttatt ggcatcgagc aatgtttccc actcatccca ctcttcactg aatgccgatt
    50101 gacgctggta gatagcatat tcacagcctg gttcataaat atgccgatag cggtagccat
    50161 ttttgatgta gggcgcagaa acttctcgtt gcggaatgcg gtcgatgatt tcctttaaga
    50221 tgcgatcctg caaggcttgt tgtgaggcca tcacccgatg accgtaacta ttttcttgtt
    50281 gcaggtagtc caggacttct ggctgagaac gcgtatcgtc ccgcagccag tagtaattat
    50341 cgatgcgcgt atcgccatga agcgtcatgg cgtggggaat gcgggcggct tttggtagca
    50401 tgttattgtt ctttctggtt gaaacatctt ataagggtgg caaaactcac cggggatgca
    50461 agcgaaacag gggagtcatt gcttagatga tgacaggtaa tggcgcggat atcgaatgtt
    50521 atgcagacag agaaaatcag cctgttcaaa tggctgtgcg attctggata gcccgaaata
    50581 gtcaacttca ggctatccag agagcggaat tattccgcca aagtgcgttt ttgctgttcg
    50641 agatcgcgtt caatgccgtc acgaacatcc tgggggattt tcagcgcgtc acccagtgca
    50701 ttcaggtaac tgcgttccat aaaatggtca atatcaatag ccgcgcaact caggaaatag
    50761 atttccagcg cctcttcttc attgcggacc ccggtagcca ggcgttgtgg atccagcggt
    50821 tgttcgattg cctgctcaat gagtacacgc ccctgctctt ccacgccggc ttcacgcaat
    50881 tgctggtcga ttgccgcacg ttctttggca tcaatatgac catcactttt agcggcaaag
    50941 accagcgcaa ggatcaaacg ttctgtacgc tcatccagcg gcgtactttg cgcgccaaac
    51001 tgcggttcgt cctgatgcgc cgcgcgaatt ttatctttgt atttattcca cagcaccgta
    51061 cccgctaccg ctccgccgcc aaccagtaac gcgttggtgc catatttcgt aagaagttta
    51121 cgtgctgatt tatttgcgac cagcagccca gccagtccgc ctaatgcgcc tggcactaac
    51181 agtttgccca atccctgatc cgcagacgag gaggtagaag aactgctttg cccaagcagg
    51241 gattgcagtt gatttaacca gttagccata tttgctcctc aataaccatt tttagtgcct
    51301 gtagcatagc ggatgaggat gtcagaaaat gtatatcgag acaaaagatg cgcaaataag
    51361 cggggcggta ggccgttatt caaagaaatt cgcgccaggt aaggtattta ctgtatatca
    51421 ggtgataagg gtattttagg tgaaagtagt ttgtcgtttt gagtggcatt gtttgatgct
    51481 gattgcccga tgcgacgctg ttgcgtcttc tcaggcctac gattgtggtg cgttctgggg
    51541 cggacaaggc actcgcgccg catccgccaa cggtcaatcg aattatcaga agccattaac
    51601 gccgctgata ttccgccatt cccgctttgc agtccacgct gacctggtaa tgaatatcgg
    51661 cacttttacc acgcacggtt agcggtactg accatttatc atctttaccc tgaatgtcct
    51721 gcaaactgac ccaagccacg ggatcggcct gaccgacaat tttttgatca tctgcccaac
    51781 gcgccacgcg attttgttga taatcacgtt ttacgctcgc ggcaattccg gcagcatcca
    51841 gaccttcaca ctttgggaaa gtgaccgact tgctggtttc attattggca gcgaaaactg
    51901 atgcgcaggc agaaaccaac aacagcccta aaaacgcccc tctttttttc atgtttttct
    51961 ccatagcaca atgattcagg agaaagcatg gtacaaattg tcaggagcgc aagttgcttc
    52021 aggccgcgtg tgaggcatct tcctcttcgg attcagcacc gacgacctgt ggggacggta
    52081 atttgccggt tttcagaatg gtgctcagca catctttttg ttctgccagc catagcgaaa
    52141 gggcttcacg ttgctcgtct tccatttgca ctggagaatt tgtcagccag gtgtcaagca
    52201 gatccgccgt atcaagcatt ttatcataag catcggcttc ctttttgctg gtaaacgaca
    52261 ttttctcttc gccctcacga atgactacgt atttaacttc aaccgccatt tgcagcctct
    52321 cataataact gtgattttat acagtatatt tcttttcggt tgagaaatca acatcagcaa
    52381 taaagacaca cgcaaacgtt ttcgtttata ctgcgcgcgg aattaatcag gggatattcg
    52441 ttatgacgtt attaggcact gcgctgcgtc cggcagcaac tcgcgtgatg ttattaggct
    52501 ccggtgaact gggtaaagaa gtggcaatcg agtgtcagcg tctcggcgta gaggtgattg
    52561 ccgtcgatcg ctattccgac gcaccagcca tgcatgtcgc gcatcgctcc catgtcatta
    52621 atatgcttga tggtgatgca ttacgccgtg tggttgaact ggaaaaacca cattatatcg
    52681 tgccggagat cgaagctatt gccaccgata tgctgatcca acttgaagag gaaggactga
    52741 atgttgtccc ctgcgctcgc gcaacgaaat taacgatgaa tcgcgagggt atccgtcgcc
    52801 tggcggcaga agagctgcag ctgcccactt ccacttatcg ttttgccgat agcgaaagcc
    52861 ttttccgcga ggcggttgcc gccattggct atccctgcat tgtaaaaccg gtgatgagct
    52921 cttccggcaa ggggcagacg tttattcgct ctgcagagca acttgctcag gcatgggaat
    52981 acgctcagca aggcggtcgc gccggagcgg gccgcgtaat tgttgaaggc gtcgttaagt
    53041 ttgacttcga aattaccctg ctaaccgtca gcgcggtgga tggcgtccat ttctgtgcac
    53101 cagtaggtca tcgccaggaa gatggcgact accgtgaatc ctggcaacca cagcaaatga
    53161 gcccgcttgc ccttgaacgt gcgcaggaga ttgcccgtaa agtggtgctg gcactgggcg
    53221 gttatggtct gtttggtgtc gagctgtttg tctgtggtga tgaggtgatt ttcagtgagg
    53281 tctcccctcg tccacatgat accgggatgg tgacgttaat ttctcaagat ctctcagagt
    53341 ttgccctgca tgtacgtgcc ttcctcggac ttccggttgg cgggatccgt cagtatggtc
    53401 ctgcagcttc tgccgttatt ctgccacaac tgaccagtca gaatgtcacg tttgataatg
    53461 tgcagaatgc cgtaggcgca gatttgcaga ttcgtttatt tggtaagccg gaaattgatg
    53521 gcagccgtcg tctgggggtg gcactggcta ctgcagagag tgttgttgac gccattgaac
    53581 gcgcgaagca cgccgccgga caggtaaaag tacagggtta aacccggcaa aaaaacgcta
    53641 caaaaatgcc cgatcctcga tcgggcattt tgacttttac agcttagcgc cttctacagc
    53701 ttcacgcgcc agcttagtaa tgcgatcgta atcgcccgct tccagcgcat ctgccggaac
    53761 cagccaggaa ccaccgatgc acagcacgct tttcagcgcc aggtagtcac ggtagttagc
    53821 cggagaaata ccacccgtcg ggcagaaacg gacctgggag aacggacccg cgatcgcctg
    53881 cagggctttc acgccgccgt tagcttcagc cgggaagaat ttgaactctt tcaaaccgta
    53941 gtccataccc agcatcagtt cggaaacagt gctgatcccc ggaattagag gaatagtccc
    54001 ttcggtagca gctttcagca gcggctcggt cagacccggg ctaattgcga actgtgcacc
    54061 cgcttcagtg acttctgcca gctgctgtgg attcagcacc gtaccggcac ccacaatcgc
    54121 ttcaggcact tctttggcga tagcacggat agcgtcaact gcacactcgg tacgcagagt
    54181 cacttccaga acgcgcaccc caccagcaac caacgctttt gccatcggca ctgcgtgttc
    54241 cagttttttt accacgataa ccggtacaac cgggccggtg gtcaggattg attctgcact
    54301 tgttttccag tttttcatca gagttttctc tcgcctgatt acaaatttgt cgtcttaaaa
    54361 agtgatacag gttgcgccct gttcggcacc ggacagtttt tcacgcaagg cgctgaataa
    54421 ttcacgtcct gtccccacgc gtgacgcgct caggtcagga atgtgcggtt cgcgagcagc
    54481 cagttccgct tcgtctacca gcagcgtcag ttcgcctgtc tgtccattca cacgaatgat
    54541 gtccccgtcg cgcacttttg ccagcagccc gccatcgtag gcttctggtg ttacgtggat
    54601 agctgacggc actttacctg aagcgccgga gagtcgtcca tcggtaacta acgcaatttt
    54661 gaaacaccgg tccaataata caccaagtgg cggcatgagt ttatgtaatt ctggcattcc
    54721 gttcgctttt ggcccctgat gacggacaac aacgacacaa tcgcggtcca gcaaacccgc
    54781 ttcaaaggcc ggcataacgt catgctggct ttcaaaaaca accgctggcg cttcaatcac
    54841 ctggttctca accggcacgg cagaggtttt cataaccgca cggcccaggt taccgcttaa
    54901 cacttttgtc ccaccatgat gagagaaagg ttgttcgaag gaagcgatca cattgctgtc
    54961 gagtgatttt tccgcccctt cccgccagtc cagttcacca ttattcagcc atggttcaag
    55021 ggtataacga gacagaccaa agcctgccac cgtattgaca tcttcatgca gcaggcctgc
    55081 tttgagcagt tcacgcacca gaaccggtac gccacctgcc gcctggaagt ggttaatatc
    55141 ggccggaccg ttcgggtaga gacgtgccat cagcggtaca acatcagaaa ggtcagagaa
    55201 gtcatcccag ttaatctgaa taccggccgc gcgcgccatc gccaccaggt gcatggtgtg
    55261 gttagtggaa ccaccggtcg ccagcagtgc aacgataccg ttcaccacca ctttctcatc
    55321 gatcatctta ccgatcggca tccattcatt accattaccg gtcatgcgtg taacctgacg
    55381 cgcagcggca gcggtcaaag catcgcgcag cggagaatcc ggatgaacaa aagaagagcc
    55441 tggcaactgc atccccataa attccaccac catctggttg gtgttggcag taccgtagaa
    55501 agtacatgtt cccggcgcat ggtaagacgc ggcttctgac tccagtaagg ccatgcggtc
    55561 cactttacct tcggcataaa gctggcgaat acgcactttt tctttatttg gcaaaccgct
    55621 tgccatcggt ccagacggca caaacaccgc aggcaaatga ccaaacgaca gggctgccat
    55681 cgtcagaccc gggacaatct tgtcgcacac accgaggaac agagcaccat caaacatgtt
    55741 atgggacagc cccaccgccg cagacatcgc tatcacttcg cggcttagca gcgacaattc
    55801 cattccatcc tgcccctggg tgacaccatc acacatcgcc ggaacaccgc ccgcaacctg
    55861 accaaccgca ttcgcttcat gcagggcttt acgaatgatt tctggatagt gttcataagg
    55921 ctggtgcgcg gagagcatgt cgttatagga ggtgatgatg gcgatattgt tacgcaacat
    55981 gcttttcaaa gaggctttgt cttctggctg gcaggcagcg aaaccgtgtg ccaggttacc
    56041 gcatgccaac tgcgaacgat gaacggtcga cgttttcgct tgttctatcc gggcgagata
    56101 agcagagcga gtctcgcgcg aacgttcaat gattcgattt gttacgcgta acaattgtgg
    56161 attcataaag gctcctgaaa ttgagttgtc agagcaggat gattcacaac gcgtttcatt
    56221 cagaggattt atgagtgaaa cgcctgtaac cggagctcat agggcaaaaa cgtttcagtc
    56281 agtgtaataa aaaaagcctc gtgggtgaat ccgcacgagg cctgaaagtg taaaaattgt
    56341 tctacaatct gtgcaagatc atgttaccgg taaaataacc ataaaggata agcgcagata
    56401 ttactcaaac tcattccagg aacgaccatc acgggtaatc atcgccaccg aggcaacggg
    56461 tccccaggtt ccggcctgat acggtttcgg cgcatcattg tccatcgccc acgcctcagt
    56521 aatggagtct acccatttcc aggcttcttc cacttcgtcg cgacgtacaa acagtgcctg
    56581 aataccacgc atggtttcca gcagcaaacg ttcataggca tccgccagat gcgtctgatt
    56641 aaaggtttct gaatagctca gatccagctt ggtgatttgc aggttatgtt tgtggtcaag
    56701 gccaggaact ttattcagta cctggatatc cacgccttca tcaggttgca gacggatagt
    56761 cagtttattc tgcggcagat cctgccacga ctctttaaac agattcagtt caggtgtttt
    56821 gaaatagacc acgacttcag aacatttggt cggcagacgt ttaccagtac gcaggtagaa
    56881 tggcacaccg gcccagcgcc agttatcaat gtcgacgcgg atcgccacga aggtttctgt
    56941 attgctgctc ttgttcgcgc cctcttcttc cagatatccc ggcacttttt tgccctgggc
    57001 gaagcccgca gtatattgcc cgcgtacggt tttttcgcgt acgttgtagc ggtcgatgcg
    57061 gcgcagagac ttcagtactt tcactttttc atcgcggatg ctgtctgcgc tcaggtcaga
    57121 cggcggagac atcgcaatca tgcaaagaat ttgcagcagg tggttctgga tcatgtcgcg
    57181 catctgaccg gctttatcaa aatagcccca gcgcccttcg atccccactt cttctgccac
    57241 ggtaatctca acatgatcaa tggtgcgatt gtcccagtta ttcacaaaca gggagttagc
    57301 aaaacgcagc gccaacaggt tcagcaccgt ttctttacca agatagtggt cgatacggta
    57361 aacctggcac tcctcgaagt attcgccaac ctgatcattg atttcctgcg aggtcgccag
    57421 cgacgtcccc agcggtttct ccatgactac gcgtgccggt ttagcattca gttttgcctc
    57481 gccaagccct ttgcaaattg cgccaaaagt gctgggcggc atggcaaagt agttaatggt
    57541 gatacgattt ttttgatcca gcatcgcgcc gagacggctg aatgcagcag tgtcattgac
    57601 atcgagatta caaaaatcca gacgtgcact cagggtgtcc cataaacctt catcaatggt
    57661 ttctttcatg aaagtttcga gcgcctcgcg gacaactttg gtatatgccg ctttatccca
    57721 gtcagcacgc cctacgccga taatccgggt gtccgggttg agctgaccgg ctttttccag
    57781 ttgatacagg gaaggcagca atttacgacg cgcaaggtcg cctttcgcgc cgaaaatgac
    57841 caggtcacag gcctgggctg tttgcgttac cgccatgtca ttctccttaa gttaactaac
    57901 ccggtactta agccagggta tacttgtaat tttcttacgg tgcactgtac tgcttttacg
    57961 agcttgcgaa aactgtaaac gcttatccac ccgtgcgatt acgggaaaag cgcgcaaagt
    58021 gcggcaaaac tgataaaaaa atcatcgttt tccattgggt aaaaatctga cactgatcat
    58081 gttatgaaaa aaaataacaa cttttttatc tgcttttgtc attaacacgg cacacaggcg
    58141 taatatctga caaaactgca tttcgatttc tttcagtgcg gaaatcgtca ttacccgtga
    58201 gtctctttac atcatgaata tgctggaaaa aatccagtct cagctggaac atttgagcaa
    58261 atcagagcgc aaagttgccg aggtcattct ggcttcgccc gataacgcga tccattcgag
    58321 tattgctgct atggcactgg aagccaatgt tagcgaaccg acggtgaatc gtttctgtcg
    58381 cagcatggac acgcgcggtt ttcctgattt taaacttcat ctggcacaga gtctggcgaa
    58441 tggcactccc tatgttaatc gcaatgtcaa tgaagatgac agcgttgaat catacacagg
    58501 gaaaatattt gagtccgcaa tggcaacgct tgatcatgtc cgtcattcac tggataaatc
    58561 tgccatcaac cgcgccgtcg acttgctcac tcaggcaaaa aaaatcgcct ttttcggatt
    58621 aggctcttca gccgccgttg cccacgatgc gatgaataag ttctttcgtt ttaatgttcc
    58681 ggtggtgtac tccgatgata tcgtgctgca acgcatgagt tgtatgaatt gtagcgacgg
    58741 agacgtggtg gtgctgattt ctcacactgg aagaacaaaa aatctggtcg agctggcgca
    58801 gctggctcgc gaaaacgacg ccatggtgat tgccctcacc tctgcgggta ccccgctcgc
    58861 ccgggaagca acgctggcaa ttaccctcga cgtaccggaa gatactgaca tttatatgcc
    58921 catggtttct cgacttgcac agctgaccgt gatagatgtg ctggcgacag gatttacttt
    58981 gcgacgcggt gcaaaattca gagataactt gaagcgggtc aaggaagcgc tgaaggaatc
    59041 gcgttttgat aagcagttac ttaatttaag tgacgatcgc taaaaacgac tgtcactgtc
    59101 ctaatcttat acgacatccg aatgagatta atttatcgcc atcgcggcgt tatttcattc
    59161 ggatttcatg ttcaagcaac acctggttgt ttcagtcaac ggagtattac atgtccagaa
    59221 ggcttcgcag aacaaaaatc gttaccacgt taggcccagc aacagatcgc gataataacc
    59281 ttgaaaaagt tatcgcggca ggtgccaacg ttgtacgtat gaacttttct cacggctcgc
    59341 ctgaagatca caaaatgcgc gcggataaag ttcgtgagat tgccgcaaaa ctggggcgtc
    59401 atgtggctat tctgggtgac ctccaggggc ccaaaatccg tgtatccacc tttaaagaag
    59461 gcaaagtttt cctcaatatt ggggataaat tcctgctcga cgccaacctg ggtaaaggtg
    59521 aaggcgacaa agaaaaagtc ggtatcgact acaaaggcct gcctgctgac gtcgtgcctg
    59581 gtgacatcct gctgctggac gatggtcgcg tccagttaaa agtactggaa gttcagggca
    59641 tgaaagtgtt caccgaagtc accgtcggtg gtcccctctc caacaataaa ggtatcaaca
    59701 aacttggcgg cggtttgtcg gctgaagcgc tgaccgaaaa agacaaagca gacattaaga
    59761 ctgcggcgtt gattggcgta gattacctgg ctgtctcctt cccacgctgt ggcgaagatc
    59821 tgaactatgc ccgtcggctg gcacgcgatg caggatgtga tgcgaaaatt gttgccaagg
    59881 ttgaacgtgc ggaagccgtt tgcagccagg atgcaatgga tgacatcatc ctcgcctctg
    59941 acgtggtaat ggttgcacgt ggcgacctcg gtgtggaaat tggcgacccg gaactggtcg
    60001 gcattcagaa agcgttgatc cgtcgtgcgc gtcagctaaa ccgagcggta atcacggcga
    60061 cccagatgat ggagtcaatg attactaacc cgatgccgac gcgtgcagaa gtcatggacg
    60121 tagcaaacgc cgttctggat ggtactgacg ctgtgatgct gtctgcagaa actgccgcag
    60181 ggcagtatcc gtcagaaact gttgcagcca tggcgcgcgt ttgcctgggt gcggaaaaaa
    60241 tcccgagcat caacgtttct aaacaccgtc tggacgttca gttcgacaat gtggaagaag
    60301 ctattgccat gtcagcaatg tacgcagcta accacctgaa aggcgttacg gcgattatta
    60361 ccatgaccga atcgggtcgt accgcgctga tgacctcccg tatcagctct ggtctaccaa
    60421 ttttcgccat gtcgcgccat gaacgtacgc tgaacctgac tgctctctat cgtggcgtta
    60481 cgccggtgca ctttgatagc gctaatgacg gcgtagcagc tgccagcgaa gcggttaatc
    60541 tgctgcgcga taaaggttac ttgatgtctg gtgacctggt gattgtcacc cagggcgacg
    60601 tgatgagtac cgtgggttct actaatacca cgcgtatttt aacggtagag taagtacgtt
    60661 gccggatgcg gcgaaaacgc cacatccggc ctacagttca atgatagttc aacagatttc
    60721 gaatattctg aagcaaactt gaacttatca tcaggcgaag gcctctcctc gcgagaggct
    60781 tttttatttg atgggataaa gatctttgcg cttatacggc tggatttcgc ccggtttgcg
    60841 agttttcagc aattttagta tccaggtgta ttgttctggt cgcggaccaa caaaaatctc
    60901 gacttcttca ttcatccgcc gcgcaatcgt atgatcatcc gcctctaaca gatcatccat
    60961 cggtgggcgc acctgaatcg tcagacggtg cgtcttgcca tcataaatcg gaaacagcgg
    61021 aacaacgcgc gcacggcaca ctttcatcaa acgaccaatc gcgggcaacg tcgctttata
    61081 ggtggcaaag aaatcaacaa attcgctgtg ctcagggcca tgatcctgat cgggtaaata
    61141 atatccccag tagccctgac gtaccgactg gatgaatggt ttaataccat catttctcgc
    61201 atgcagacga ccgccaaaac gacgacgcac cgtgttccag acataatcaa aaaccgggtt
    61261 gccctgatta tggaacatcg ctgccatttt ctgcccttgc gaggccatca gcatggcagg
    61321 aatatcgacg gcccaaccgt gcggcaccag aaagataact ttctcgttat tacgccgcat
    61381 ctcttcgatg atctccagcc cttgccagtc aacgcgcggc tgaattttct ccggcccgcg
    61441 tattgccaac tcagccatca ttgccatcgc ttgcggcgcg gtggcaaaca tctcatcaac
    61501 aatcgcttcg cgttcagctt cactacgttc tggaaagcag agcgacagat tgattaacgc
    61561 acgacggcgt gagctttttc ccagtcgtcc ggcaaaacgt cccagccgtg ccagaatggg
    61621 atcacggaac tttggcggcg ttaaagcgat acccgccatc gctgctacgc ccagccatgc
    61681 tccccagtag cgcgggtggc gaaaggattt atcaaactca ggaatgtatt cgctattatt
    61741 ttttttcgtt tccatgcttt tccagtttcg gataaggcaa aaatcaatct ggtgatagtg
    61801 tagcggcgca acttgccccg caccaaataa aaaaagccgg tactgacttc gtaccggctg
    61861 cgaatggatg ttaattaatc aaaccgtagc tgcggcacaa tctctttggc ctgcgccagg
    61921 aattcgcgac gatcggagcc ggtcagccct tcggtacgcg gcagttttgc cgtcagcggg
    61981 tttacggcct gctggtttat ccatacttca tagtgcaaat gcggcccggt tgaacgtccg
    62041 gtattaccgg aaagcgcgat acggtcgcca cgtttcacct tctgtcccgg tttcaccaga
    62101 atcttgcgca agtgcatata acgcgtggtg tagctgcgac catgacgaat agccacataa
    62161 taacctgctg cgccactgcg tttggcaacc accacttcac cgtcacccac tgaaagcact
    62221 ggcgtaccct gcggcatggc gaaatcaaca cctctgtgtg gtgcaacgcg accggtcacc
    62281 ggattagtac gacgcgggtt aaagttagac gagatacgga actgtttcgc cgtcgggaat
    62341 cgcaagaatc ctttcgccag accagtaccg ttacgatcgt agaatttgcc atcttcagcg
    62401 cggatagcgt aataatcttt accttctgaa cgcaaacgta cgcccagcag ctggctttgc
    62461 tcacgtttac catcaagcat ttctcgagac attaataccg caaattcatc gccttttttc
    62521 agtttgcgga aatccatttg ccactgcatg gctttaatca ctgcgctcac ttcggcgctg
    62581 gttaaaccgg cgtttctggc gctggcaaca aagctccccc cgacggtacc tttcagcaga
    62641 ttgttaaccc actctccttg ctgcatttcg ctggtcattt taaaaccgtt agcggcagta
    62701 cggtcatagg ttcgggtttc acgacgagac acttcccagg tgaggcgctg cagttcgccg
    62761 tccgcggtta atgtccagga gagttgttga ccgattttca ggttacgcaa ttctttgtcg
    62821 gcagcagcca gttgggtgat atcacccata tcaataccat actgattgag aatgctgctt
    62881 agcgtatcgc cagtggaaac aacatattca tgcacgcccg cttcaccggc gattttgtca
    62941 tccagttcgt cctgaggaat ggcttcatct tcttgtgcag cttgatcaat cggctcactg
    63001 gcttcaggta agagcgaacg aatttcgttc tgttccagct caatggtttt gacaattggc
    63061 gtggcatcgc ggtgataaac atagggccgc cagacagcga cggccagagt aagaacggtg
    63121 agcgacccca acataacgcg gtgtggtcgc ggtaaattat taaacgccag ggcgacagag
    63181 cgggctatct gttgcacgta atcacttcct cattaatctc ctttcaggca gctcgcatac
    63241 tggttggcta attgactcag gaattctgaa tagcttgttt tacccagttt gatattcgtc
    63301 cccaggggat ccaacgttcc catacgaacg gatgtccctc gtgcgacgct ctcaacgacc
    63361 gctggcctga actgtggctc agcaaaaacg caggttgctt tttgctcaac caactgtgtt
    63421 cttatttcat gtaaacgctg cgcgccaggt tgaatctcag ggttaacggt aaaatgacca
    63481 agcggtgtca gtccaaactg tttttcgaaa tagccgtaag catcgtgaaa aacgaaataa
    63541 cctttcccct tgagcggcgc gagctcgtta ccaacctgcg tttcggttga ggctaattgt
    63601 gcctcaaaat ccttcaggtt ggcgtcaagt ttggctcgac tttgcggcat aagttccact
    63661 aattttccat ggattgcaac cgctgtagcc cgcgctatct ctggggaaag ccaaagatgc
    63721 atgttgaaat cgccgtgatg gtgatcttcg tcactttttt ccgcgtggtc gtgatcatca
    63781 tcatcgccgt gaatactttt catcagtagc ggtttcacat cttcaagctg cgcaatcgtt
    63841 acctgcttcg cttctggtaa tttgcttacc ggtttttgca taaacgcttc catctccggg
    63901 ccaacccaaa cgactaagtc cgcgttctgt aagcgtttta catccgatgg acgcagtgaa
    63961 taatcatgtt ctgaagcgcc gtcaggcagt aaaacctccg tttctgttac accatcagca
    64021 atggcagaag cgatgaaccc aacgggttta agcgaagcga caacggcggc atctgcggcc
    64081 tgtgttgcac ctccccagag agcggcggat aatgctgcga aaagaagcgt ttttttatgt
    64141 aacataatgc gaccaatcat cgtaatgaat atgagaagtg tgatattata acatttcatg
    64201 actactgcaa gactaaaatt aacatgacaa gtctggtttc cctggaaaat gtctcggttt
    64261 cttttggcca acgccgcgtc ctctctgatg tgtcgctgga acttaaacct ggaaaaattt
    64321 tgactttact tgggccaaat ggcgcaggta agtcgacact ggtacgggta gtgctcgggc
    64381 tggtaacacc cgatgaaggg gttatcaagc gcaacggaaa actgcgcatc ggctatgtac
    64441 cgcagaagct gtatctcgac accacgttgc cactgaccgt aaaccgtttt ttacgcttac
    64501 gccctggtac acataaagaa gatattttgc ctgcactgaa acgtgtccag gccgggcacc
    64561 tgattaacgc accgatgcaa aagctctctg gtggcgaaac gcagcgtgta ctattagcgc
    64621 gagcattgtt aaatcgcccg caattattag tgctggatga acccactcaa ggcgtggatg
    64681 taaatggcca ggtggcgtta tatgacctta ttgaccaact gcgtcgtgaa ctggattgtg
    64741 gcgttttaat ggtttctcac gatctgcatc tggtgatggc aaaaaccgat gaagtgctgt
    64801 gcctgaatca ccacatttgt tgttccggca caccggaagt tgtttccctg catccggagt
    64861 ttatttcaat gtttggtcct cgtggtgctg aacaactggg tatctatcgc catcatcata
    64921 accatcgtca cgatttacag ggacgaattg ttttgcgtcg gggaaatgat cgctcatgat
    64981 tgaattatta tttcccggtt ggttagccgg gatcatgctc gcctgtgccg cgggtccgct
    65041 gggttcgttt gtagtctggc gtcgtatgtc ttatttcggt gatacgctgg ctcatgcctc
    65101 attacttggc gtcgcgtttg gtttgttgct ggacgtgaat ccattctatg cggtaattgc
    65161 cgttacgctg ctcctggcgg gcggtctggt atggctggag aagcgtccac agctggcgat
    65221 tgacacgtta ttagggatta tggcgcacag tgccctgtcg ctgggcctgg tggtcgttag
    65281 tctgatgtct aacattcgtg ttgatttgat ggcttacctg ttcggtgatt tgctggcagt
    65341 gacgccagaa gatctcatcg ctattgcgat tggcgtggtc atcgtggtgg ctattttgtt
    65401 ctggcaatgg cgcaatttgc tgtcgatgac gattagcccg gatctggcgt ttgttgatgg
    65461 tgtgaaatta cagcgcgtga aattgttgtt gatgctggtg acggcattga cgattggtgt
    65521 agcgatgaaa tttgttggcg cgttgattat tacttcactg ctgattattc ctgcagctac
    65581 tgcgcgtcgc tttgcccgta cgccggaaca gatggctggt gtcgctgttt tggtggggat
    65641 ggtggcagta actggcggtt taaccttttc cgcgttttac gatacgccgg cgggtccgtc
    65701 ggtggtgcta tgtgcggcac tgttatttat tctcagtatg atgaaaaagc aggccagcta
    65761 atctatcgct gaacacattt gtcggatgcg gcgcgagcgc cttatccgac ctacggttcg
    65821 ctatctctgg taggccggat aagacgcgaa tagcgtcgca tcaggcacac tgccaatgtc
    65881 ggatgcggta cgagcgacca atccgactta cggcatttct ggcggcgtta tgccaaagtg
    65941 attccacgcc cgcgtcgtcg ccatacgccc acgcggtgta cgctgcaaaa agccttgctg
    66001 aatcagataa ggctccagca catcctcaat ggtttcacgt tcttcgccaa tagccgccgc
    66061 caggttatcc agacctacag gcccaccaaa gaatttatcg attaccgcca gcaacaattt
    66121 gcggtccata taatcaaaac cttcagcatc gacattcagc atatccagcg cctgagcagc
    66181 gatatctgcc gagatggtgc catcgtgctt cacttcggcg aaatcacgca ctcgacgcag
    66241 cagacggttg gcaatgcgcg gcgtaccgcg agcgcgacga gcaacttcca gcgcgccgtc
    66301 atcactcatc tcaagcccca taaagcgtgc gctgcgactg acgatatatt gcagatccgg
    66361 cacctgataa aactccagac gttgcacaat accaaaacgg tcgcgcaacg gtgatgtcag
    66421 cgaacctgcg cgtgtggttg caccaatcag ggtaaacggc ggcaaatcaa ttttaatgga
    66481 gcgtgccgcc ggaccttcac caatcatgat atccagttgg tagtcttcca ttgccggata
    66541 caacacctct tcaacaactg gcgatagacg gtggatctca tcaataaaca gcacgtcatg
    66601 cggttcaagg ttagtgagca tcgctgccag atcgcccgcc ttttccagca ccggaccaga
    66661 agtcgtgcgt aaattaacgc ccatttcatt ggccacaatg ttggcaagcg tagttttacc
    66721 caaccccgga ggaccaaaaa tcaacaaatg atcgagggca tcgccgcgca gtttcgctgc
    66781 tttgatgaaa atctccatct gtgaacgaac ctgcggctga ccaacatact cttccagtaa
    66841 tttagggcga atggcgcgat ctgctacatc ttccggcaaa gtggtaccgg cagaaatcag
    66901 acggtctgct tcaatcatcc tttacctcat aacgcggcgc gtagggcttc gcgaattaat
    66961 gtttcactgc tggcgtcagg gcgagcgatt ttgctcacca tgcggcttgc ttcttgtggt
    67021 ttatagccca gcgccaccag cgcggcaacc gcttcttgtt cagcatcgtc ggtcgccggg
    67081 ctggcaggag acgtgagcac cagatcggcg gctggcgtaa agagatcgcc gtgcaaacct
    67141 ttaaatcggt ctttcatttc gacaattaaa cgctcggcgg tttttttacc aatgcccggc
    67201 agtttcacca gtgctcccac ttcttcacgt tcaacggcat taacgaactg ctgcgctgac
    67261 attccggaga ggatcgccag cgccaacttc gggccgacgc cgttggtttt gattaactct
    67321 ttaaacaacg tgcgctcttg cttattgtta aagccgtaca gcagctgcgc gtcttcacgc
    67381 accacaaagt gggtgaaaac gatcgcttcc tgacccgctt cagggagttc ataaaaacag
    67441 gtcatcggca tatgcacttc atagcctacg ccgcccactt caattaacac cagcgggggt
    67501 tgtttttcaa tgatgatgcc tctgagtctg cctatcacat gacgctcctg cgtaatgaat
    67561 caaagataat gctgtatgat aaaaaaatgc tggatagata tccagcgaag gatgaagaaa
    67621 acttgcgagg cgtcccaacg atctgaaaaa tggcgcagta taatttattc tacaggttat
    67681 attggaagca aatatttgaa tattacatat tcagtgaaga aatgcgtaat aaaaatatac
    67741 attgcgactc ctgaaataat aaatttttta tgctattacg tatattcata tctatttcaa
    67801 tggaatgaca acgtgaatat taattaccct gctgaatatg aaattggaga tatcgtcttt
    67861 acatgtatag gtgctgcctt atttggtcaa atatcagctg catcaaattg ctggagtaat
    67921 cacgtcggga tcattatcgg tcataacggt gaagacttcc tggttgcaga aagccgggtt
    67981 cccctttcaa ccatcaccac gctatctcgt tttattaaac gttcgtctaa tcaacgctat
    68041 gctataaagc gattagacgc tgggctgaca gaacaacaaa aacaacgaat tgttgaacag
    68101 gttccctccc ggctacgcaa actttaccac accggtttta aatacgaatc ttcgcgccag
    68161 ttctgttcaa aatttgtttt tgatatttat aaagaagcgc tatgcattcc ggtgggtgaa
    68221 atagaaacgt ttggagaact gttaaatagc aatccgaatg caaaactcac tttctgaaaa
    68281 ttctggttct taggttctat tccgtgggag cgtaaaaccg tcacgccagc cagtttgtgg
    68341 catcatccgg gtttggtgtt gattcacgcg gagggagttg aaacgcctca gcctgaactg
    68401 accgaggcgg tataacttaa cgcagtcgcc ctctcgccag gttcagccgc gattcgctca
    68461 tctgcatcgc attctgacta acgtggcagt gggtgatggc aatcgccagt gcatcggcgg
    68521 catccgcttg tggattagcg ggcagtttca gcaaggtgcg gaccatatgc tgcacctggc
    68581 ttttctcggc gctaccaatg cctaccaccg tttgctttac ctgacgtgcc gcgtattcaa
    68641 atactggcaa ctcctgattc accgccgcca caatcgccac gccgcgcgcc tggcccagtt
    68701 tcagggctga gtcagcgttc ttcgccataa agacttgttc aatggcgaaa taatcaggct
    68761 ggaactgggt gatgatttcc gtcacgcccg catagatgag cttcagacga gacggtaaat
    68821 catccacttt ggtgcgtatg catccgctac ccaggtagga cagttgcctg cctacctggc
    68881 gaattacgcc atagccggtc acgcgcgaac ccggatcaat gccgagaata atagccatca
    68941 cgcgtctccg ttttgctgtt tagcaggcct catcagagag tcgctgcgac ctcatcagag
    69001 atttcaccgt tatggtaaac ttcctgcacg tcgtcgcaat cttccagcat atcgatcaga
    69061 cgcatcagtt tcggtgcggt ttctgcatcc atatcagctt tggtggacgg gatcatggaa
    69121 acttccgcgc tgtctgcttt cagacctgcc gcttccagag cgtcgcgcac tttacccatt
    69181 tcttcccatg cagtgtagac atcaatcgcg ccgtcatcat aggtcacaac gtcttcagca
    69241 cctgcttcca gagctgcttc catgatggtg tcttcatcgc ctttctcgaa ggagatcacg
    69301 ccttttttgc tgaacagata ggctacggaa ccatctgtac cgaggttacc gccacatttg
    69361 ctgaatgcat gacgcacttc agcaacggta cggttgcggt tgtcagacag acattcaatc
    69421 atgattgccg tgccgccagg accgtaacct tcgtagatga tggtttccat gtttgcatca
    69481 tcatcaccgc ccacaccacg tgcaattgcg cggttcagtg tgtcacgggt catgttgtta
    69541 gacagtgctt tatccaccgc cgcacgcaga cgcgggttag cgtccggatc gccaccgccc
    69601 agcttagccg cggttaccag ctcacgaatg attttagtga agattttacc gcgcttagca
    69661 tcctgcgcag ctttacgatg tctggtgttg gcccatttac tatgacctgc cataaaaata
    69721 tctccagata gccctgcctg ttcaggcagc gttaattaca aactgttcaa tcgcctgccg
    69781 gttgctccag gacttagtga gcgccgccgc agcaggcgca tcaagccact tgtaagccag
    69841 atgttcagtg aaaacgatct gccgctcgtg cggaagcgca agacagaacc atgattccgt
    69901 attacgcgtc acgcccggcg catagcgatg acgtaaatgt gaaaaaattt caaactctac
    69961 cgtgcgctga cagtcaatta aggtcagttg ttcagcgaca acatcaatgg tgacctcttc
    70021 ctttacttcg cgcatggcag cttgcggcgc ggtttcaccc tcttccacgc tgccggttac
    70081 cgactgccag aaatcgggat cgtcacgccg ctgcaacatc agcacccgtt tcgtatcttg
    70141 tgcatagatg accactaaga tcgaaacggg acgcttatac actttatcct ccacgctgcc
    70201 tcttcgttga ctgccttcgc tcatcccatt cacatagtta tctatgctca tgggagttca
    70261 ctcagttgcc gccttgatgc aacgcgaatg atttcgtgta tttgagtcat atcagttatt
    70321 ctcagccttc ttcacaacct gaatgctcag ctcagccagt gcagtcgggt tagcaaagct
    70381 cggtgcttca gtcatcagac acgctgccgc cgtggttttc gggaaggcga taacgtcacg
    70441 gatattgtcg gtgccggtca gcagcatggt cagacggtca agaccgaatg ccagacctgc
    70501 gtgcggcgga gtaccgtatt tcagagcgtc gagcaggaag ccgaatttct cgcgctgttc
    70561 ctcttcgttg atacccagaa taccaaacac cgtctgctgc atatcaccat tatggatacg
    70621 tactgaacca ccgcccactt cgtaaccatt gatgaccata tcgtaagcgt tcgccaccgc
    70681 attttccggt gcagctttca gttctgcagc agtcatgtct ttcggtgagg tgaacggatg
    70741 gtgcattgcc gtcaggccgc cttcaccgtc gtcttcaaac atcgggaagt cgataaccca
    70801 cagcggtgcc catttgcttt cgtcggtcag accaaggtct ttacccactt tcaggcgcag
    70861 tgcgcccatc gcgtcggcaa caattttctt gttgtcggca ccgaagaaaa tcatatcgcc
    70921 atcttgcgcg gcagtacgat ccaggatggc ttcgatgatt tctgcattaa ggaacttcgc
    70981 taccgggctg ttgatacctt ccagaccttt cgcgcgttcg ttaactttga tgtaagccag
    71041 acctttcgcg ccgtagattt taacgaagtt accgtattcg tcgatctgct tacgggtcag
    71101 cgatgcgccg cccggaacgc gcagagcggc aacgcgacct ttcggatcgt tcgccggacc
    71161 tgcaaatact gcaaactcaa cagatttcag cagatcagca acgtcggtca gttccatcgg
    71221 gttacgcaga tccggtttat cagaaccata acggcgttct gcttccgcaa aggtcattac
    71281 cgggaaatcg cccagatcca cgcccttcac ttccagccac agatggcgca ccagcgcttc
    71341 catcacttca cgcacttgcg gcgcggtcat gaaagaagtt tccacatcga tctgagtaaa
    71401 ttcaggctga cgatcagcgc gcaggtcttc gtcacggaag catttaacga tctgatagta
    71461 gcggtcaaag ccggacatca tcagcagctg tttgaacaac tgcggggatt gtggcagcgc
    71521 gtagaattta cctttgtgca cacgagaagg caccaggtag tcacgcgcgc cttccggcgt
    71581 ggctttggtc agcatcggag tttcgatgtc gaggaagccg tggtcatcca taaaacggcg
    71641 caccaggctg gtgattttag cgcgggtttt caggcgctga gccatttccg ggcgacgcag
    71701 gtcgaggtag cggtatttca gacgcgcttc ttcggtgttg acgtggttag agtcaagcgg
    71761 cagaacatct gcgcggttga tgatagtcag cgaggacgcc agcacttcga tttcgccggt
    71821 cgccatatcg cggttaatat ttttttcgtc acgcgcacgt acggtgcccg tgacctgaat
    71881 gcagaactca ttacgcagtt cagaggccag ctttaacgcg tccgcacgat ccggatcgaa
    71941 aaatacctgc acgatacctt cgcggtcgcg catatcgatg aagatcaggc taccaagatc
    72001 acgacgacgg ttgacccaac cacacagagt cacctgctgc cccacgtggg acaaacggag
    72061 ctgtccacaa tattctgtac gcatgagata tcccttaact tagctgccgg cggatgcccc
    72121 ctgctgcgca ggtgaccaag tcgcagcgtt agctgtatgt cacaactgaa tgaaaaaagg
    72181 cggctattat actggaaatt ctgccgcacc gtaagagcct ggcccgcgct ggaacgcctc
    72241 gttaccactt tatatcgggc ctgaaatcag actctacgcc agtttgctat aaaggtgttg
    72301 cccgaactca taaaaattaa caaaatttgt cgttccgcca tcggctaatc gcattaaggt
    72361 gtgaggcacg attttgtttt ttcaggagtc attatgcttg aacttaatgc taaaaccact
    72421 gcgctggtgg tgatcgattt acaagaaggc atcttacctt ttgccggtgg tccacatact
    72481 gccgatgagg tagttaatcg cgccgggaag ctggcggcga aatttcgcgc cagcggtcag
    72541 cccgtgtttc tggtgcgcgt tggctggtct gccgattacg ccgaagcatt aaaacagccg
    72601 gttgatgccc cctcccccgc taaagtgttg cccgaaaact ggtggcaaca tccagctgca
    72661 ttaggtgcaa ctgacagtga tatcgaaatc atcaaacgtc agtggggtgc gttttacggt
    72721 acggatctgg agttgcaact gcgccgccga ggtatcgata caatagtgtt atgtgggatc
    72781 tcgaccaata tcggtgttga atccaccgcc cgcaatgcct gggaacttgg ctttaatctg
    72841 gtgattgccg aagacgcctg tagtgccgct agcgccgagc agcacaataa cagcatcaac
    72901 catatctacc cacgcatcgc ccgtgtgcgt agcgtggaag agatccttca cgcgttatga
    72961 tttacatcgg tctaccgcaa tggtcgcatc ctaaatgggt gcggttgggg atcaccagcc
    73021 ttgaagagta tgcccgccac tttaactgcg tgatacggga tttttaaaaa tcactaaaga
    73081 acgcccaaga gcatgtgttt tctttagcat aatcaaactg ttggattgcc atatcatatg
    73141 aaaatcggca aagttcatat gtaacaaagt gtcccaatca tgccccaaaa tgccccacaa
    73201 cagatatttt tgtcccatgc atgccccaaa aaatcacttt ccctcgcctt gacactgttt
    73261 atccgtacag ttaaaaataa tactgtatac aaacacagtg tagggggatt tttatgcgta
    73321 ttgaaatctg catagccaaa gaaaaaatga ctaaaatgcc aaccggtgct gtggatgcgt
    73381 taaaggatga attaaccaga cgcatcagta agcgttatga cgatgtagag gtgatcataa
    73441 aagcaaccag caacgatgcc ctttcagtta cccgcatcac cgataaagat tctgcaaaaa
    73501 catttgttca ggagactctg aaagatacct gggagtctgc tgacgagtgg tttgttcact
    73561 aataaacacg taaaatcggt aacggctgga aatcattcaa tcctcgcact atcgaaaagc
    73621 tcaccagtca acagcggtaa gttctttcat acgacgtacc gctgttttct ttatgattga
    73681 tagctgtact ggtaaattat gagcaatctg aatccatgca tgacgtatgg cgcctgttgt
    73741 gcatttttcc gcgtctcttt ttaccagagc aaaaccaatg atactgacgt agttgtctcc
    73801 cagagactta tgcctgtata gcaaacctca aataatctgg gatctcattt cgtagtttca
    73861 caatatcaat atccgaatcg atatgtttct ggtaaaactt gtccgcaagc aagtttgcta
    73921 tgctatctga tgtacgattt tttacatccc ggctcatacc atcacaaaga gcatctattt
    73981 tcttgccaaa agaagcattc cccattatta catgattaat agaactttgt gctgccttaa
    74041 tatcaagact tagttgatat ttttgactca caagagaaaa gactctttgc ttcacttcag
    74101 tagtaatttt ttcatttctt tgaagacagt aattatcaat ctcctgattg atcacccttg
    74161 atggatatac catctgttca tctttcaccc acccatcaat atttttagca ctctgcctgc
    74221 gcactgtatc cagtatattg ccgctaaatt tgtcaacaga aaagcgaata gtccgctctc
    74281 caattgaaca ttttatgacc tcatcattct tccctcggaa agggttccga aaggaatttt
    74341 ctctatgaca acttacacca aaagagctga aagatgtacc tgtagtcttc atcggcatgg
    74401 taattccttt ttataaaaat atgtttacaa gattgcatac ttgtgtttat tgtagccaga
    74461 aaaaacacac atgcaaataa cattctatta gaagttgtaa tgtttgagtt acatatcatg
    74521 atcggtatgt tgacttttgt taccaatata gttcacaaaa tgggttgaaa aggataataa
    74581 tatgcctgtc atattaaatt tttctaatgg aagtgtattg ccggaaaatg agctggaggc
    74641 tttacggcat attgcaagaa gcaatcagaa tgacactatt accataggaa gccgtaatat
    74701 gaggcttcat tatatccagt ttatggatgg ttttagtgta gagcctattc ctggtggact
    74761 tagggaccgt cttggggcaa gagagactca tcatctcgca gacagcctga caagacagct
    74821 taacggaggt aacacttttc tgcaggcata cagcttatat ctggagcaga ggcacgctgc
    74881 cccgcttgtg caggaaagcg tcataaaaac actactggat cgaataaatt tgaatgcatt
    74941 tcccgttagt ttacaagact tttcctgtac tgaggagtat cttaattgtc cgataacgct
    75001 acatattcct gaaaccggtg tttttgtcag aaatgctcta agttcagaaa tatgtgcatt
    75061 atatgatcag aaagcattga ctgaacttat tcggcgcaac gccctacatc cattcagccg
    75121 tgaacccttt tctccagaaa tgattataag aaaagagaca tgtcatttta atatagcaaa
    75181 acaatgtttt tgcgcattcc ccatatacac ccttcaacaa aatagtattt aaaaataaaa
    75241 atacaatata agaagcatat tttcaataat ttaatcacca tataacaaac atatagagag
    75301 gagactgttt atgcccaaaa tatcatcagt tgtatcatca tgttactatt tgttcagaga
    75361 acatcaacaa ctttcaaatg aaacaacaat gacgaactcc gcctccagaa gaattgttca
    75421 taaagaacat ggtatatctt taaaatccgt tcccgtatgg ttggctacag ctaaaactcc
    75481 ccttgctcta ctcaatggca aacatacaag aagtcactca tttattattg cagggacccc
    75541 aggaatggga ggcaggagcg gagcccaata ctatgccata aacagtgatg ataaacgctc
    75601 ccgcatagac attgactctt tatttttaaa aaagttaaat aatgcgcgaa atcaaaataa
    75661 attttcaatc gatgtaaaag aaacggttat aaaactacaa ggacaaaaat ttacatgcat
    75721 tgaagatttt cataaaaagt atagtgaaat caggctaaag accaatagca atattcaaca
    75781 aaaacaaatt acagatgaag taaaatcact tacatatttg attccttcag aaaaaaaaga
    75841 gatgtggata tataaaaaca atggaaaaga taatgcaaaa ccaaacttag gagagcgaga
    75901 cgtaagaatg ttcgaaaata ttagtcctga tgatacagat aagataacag gaaggaaatt
    75961 ttcagagtta ggtgagtatc tttattcagg aaatgtcata aaactcagtc agttatcaat
    76021 tcgttaccta cccaatatca actcaatctc attaatagag acaaaacaga gtttgttgct
    76081 acatcgatta tattcagatg aagtacttca gagaaatgga acacttatcc cgacaccact
    76141 acatgaagaa aaatcaattc ccgctgccaa tataaaaaca atgctcaaca acataccaac
    76201 ttacaaaatg ttaccgccat tcacagaaac acaaggtaat tgttcttctg gcgcagccac
    76261 gtttttacgc aaatcaggca ccgaagaaaa agatattctt gcatgtagcc cccgaaatta
    76321 tgggctgcat cataacataa aaacatggga ccccttggtt agaaattaag gatccaaata
    76381 ttatatattt catataaagc aaggaaaata ttgcctgaat aattgttcag gcaatatatc
    76441 cttacatggc actattataa taaactatta atataaaaac acaccaacag aaaaaattaa
    76501 gcatcacttg caacaaaggc ttcttttttt gaatcaaagt gacattcgtc ttttctcatg
    76561 atcattgatt ctgttatagg ttctcgactc agaggatgag ctccaccagt ttcaacaagt
    76621 tgcactaacg cgtccttatc atatagagag catatctcag cacctcgtga gtttctcatg
    76681 aacactccat tctcaggtgt gtccagcgtt atcgggcatg tcaaaaatga ctccgggcaa
    76741 gaaaagtgat tagaatccgg tctaaata
//
LOCUS       DAZUDJ010000014        76172 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.014, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000014 DAZUDJ010000000
VERSION     DAZUDJ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 76172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76172
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.014"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(225..1874)
                     /gene="actP"
                     /locus_tag="ACHY1N_001381"
     CDS             complement(225..1874)
                     /gene="actP"
                     /locus_tag="ACHY1N_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015123 - acetate transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015370 - solute:sodium symporter activity
                     [Evidence IEA];
                     GO_function: GO:0031402 - sodium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HFS4043715.1"
                     /translation="MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAG
                     HLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     KKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAF
                     LGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH"
     gene            complement(1871..2185)
                     /gene="yjcH"
                     /locus_tag="ACHY1N_001382"
     CDS             complement(1871..2185)
                     /gene="yjcH"
                     /locus_tag="ACHY1N_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HFS4043716.1"
                     /translation="MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLI
                     AFAPGWLGTPLNPNTSVTRGIPIGVGVIVISFVLTGIYIWRANGEFDRLNNEVLHEVQ
                     AS"
     gene            complement(2385..4343)
                     /gene="acs"
                     /locus_tag="ACHY1N_001383"
     CDS             complement(2385..4343)
                     /gene="acs"
                     /locus_tag="ACHY1N_001383"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003987 - acetate-CoA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0016208 - AMP binding [Evidence IEA];
                     GO_process: GO:0019427 - acetyl-CoA biosynthetic process
                     from acetate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HFS4043717.1"
                     /translation="MSQIHKHTIPANIADRCLINPQQYEAMYQQSINVPDTFWGEQGK
                     ILDWIKPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAVAGRIIDSNSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVV
                     VLKRTGGKIDWQEGRDLWWHDLVEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINP
                     EAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVD
                     NEGNPLEGATEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            4735..6171
                     /gene="nrfA"
                     /locus_tag="ACHY1N_001384"
     CDS             4735..6171
                     /gene="nrfA"
                     /locus_tag="ACHY1N_001384"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0005509 - calcium ion binding [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0042279 - nitrite reductase (cytochrome,
                     ammonia-forming) activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HFS4043718.1"
                     /translation="MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNET
                     FAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVR
                     ETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGC
                     ADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQ
                     SINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIEIPDISTKEKAQQAIGLNMEQ
                     IKAEKQDFIKTVIPQWEEQARKNGLLSQ"
     gene            6216..6782
                     /gene="nrfB"
                     /locus_tag="ACHY1N_001385"
     CDS             6216..6782
                     /gene="nrfB"
                     /locus_tag="ACHY1N_001385"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HFS4043719.1"
                     /translation="MSVLRSLLTAGVLASGLLWSLNGITATPAAQASGDRYEVTQQRN
                     PDAACLDCHKPDIEGMHGKHASVINPNNKLPVTCTNCHGQPSPQHREGVKDVMRFNEP
                     MYKVGEQNSVCMSCHLPEQLQKAFWPHDVHVTKVACASCHSLHPQQDTMQTLSDKGRI
                     KICVDCHSDQRTNPNFNPASVPLLKEQP"
     gene            6779..7450
                     /gene="nrfC"
                     /locus_tag="ACHY1N_001386"
     CDS             6779..7450
                     /gene="nrfC"
                     /locus_tag="ACHY1N_001386"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HFS4043720.1"
                     /translation="MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDES
                     LCIGCTACMDACREVNKVPEGVSRLMIIRSEPQGEFPDVKYRFFRKSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTNL
                     QAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKY
                     GEVSQ"
     gene            7447..8403
                     /gene="nrfD"
                     /locus_tag="ACHY1N_001387"
     CDS             7447..8403
                     /gene="nrfD"
                     /locus_tag="ACHY1N_001387"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HFS4043721.1"
                     /translation="MTQTSAFHFESLVWDWPIAIYLFLIGISAGLVTLAVLLRRFYPQ
                     AGGADSTLLRTTLIVGPGAVILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     LYMVVLVLWLAKIFEHDLLALQQRWLPKLGIVQKVLSLLTPVHRGLETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGVAVALIAMAIRQRKNPHSTEAHFVH
                     RMEIPVVWGEIFLLVAFFVGLALGDDGKVRALVAALGGGFWTWWFWLGVAGLGLIVPM
                     LLKPWVNRSSGIPAVLAACGASLVGVLMLRFFILYAGQLTVA"
     gene            8423..10141
                     /gene="nrfE"
                     /locus_tag="ACHY1N_001388"
     CDS             8423..10141
                     /gene="nrfE"
                     /locus_tag="ACHY1N_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HFS4043722.1"
                     /translation="MDVFLPEVGFLALLLSLGVNVLTPLTAFAGVRLRWPAMMRLTCI
                     GILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWELKLAAVWGGHEGSLLLW
                     VLLLSAWSALFAWHYRQQTDPLFPLTLAVLSLMLAALLLFVVLWSDPFVRIFPPAIEG
                     RDLNPMLQHPGLIFHPPLLYLGYGGLMVAASVALASLLRGEFDGACARICWRWALPGW
                     SALTAGIILGSWWAYCELGWGGWWFWDPVENASLLPWLSATALLHSLSLTRQREIFRH
                     WSLLLAIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFSLFALISLASLALYGW
                     RARDGGPVVRFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPY
                     FNRATLPFGLLMLVVIVLATFVSGKRVQLPALVAHAGVLLFAAGIVVSSVSRQEISLN
                     LQPGQQVTLAGYTFRFERLDLQAKGNYTSEKAIVALFDHQQRIGELMPERRFYEARRQ
                     QMMEPSIRWNGIHDWYAVMGEKTGADRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWR
                     GRKRDE"
     gene            10134..10517
                     /gene="nrfF"
                     /locus_tag="ACHY1N_001389"
     CDS             10134..10517
                     /gene="nrfF"
                     /locus_tag="ACHY1N_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HFS4043723.1"
                     /translation="MNKGLLTLLLLFTCFARAQVVDTWQFANPQQQQQALNIASQLRC
                     PQCQNQNLLESNAPVAVSMRHQVYSMVAEGKNEVEIIGWMTERYGDFVRYNPPLTGQT
                     LVLWALPVVLLLLMALILWRVRAKR"
     gene            10514..11110
                     /gene="nrfG"
                     /locus_tag="ACHY1N_001390"
     CDS             10514..11110
                     /gene="nrfG"
                     /locus_tag="ACHY1N_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HFS4043724.1"
                     /translation="MKQSQIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAQYQRQRD
                     PLHQFASQQTPEAQLQVLQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQL
                     RGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY
                     AQAIELWQKVMDLNSPRINRTQLVESINMAKLLQRRSD"
     gene            11452..12765
                     /gene="gltP"
                     /locus_tag="ACHY1N_001391"
     CDS             11452..12765
                     /gene="gltP"
                     /locus_tag="ACHY1N_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006835 - dicarboxylic acid transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HFS4043725.1"
                     /translation="MKNIKFSLAWQILFAMVLGILLGSYLHYHSDSRDWLVVNLLSPA
                     GDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTIAIILGITL
                     ANVFQPGAGVDMSQLATVDISKYQSTTEAVQSSSHGIMGTILSLVPTNIVASMAKGEM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVT
                     VANFGFSSLWPLAKLVLLVHFAILFFALVVLGIVARLCGLSVWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ"
     gene            complement(12843..13532)
                     /gene="yjcO"
                     /locus_tag="ACHY1N_001392"
     CDS             complement(12843..13532)
                     /gene="yjcO"
                     /locus_tag="ACHY1N_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sel1 family TPR-like repeat protein YjcO"
                     /protein_id="HFS4043726.1"
                     /translation="MKKIIALMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADS
                     WFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSK
                     EGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKA
                     DDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDT
                     GCEEFEKLTNG"
     gene            complement(13626..15773)
                     /gene="fdhF"
                     /locus_tag="ACHY1N_001393"
     CDS             complement(13626..15773)
                     /gene="fdhF"
                     /locus_tag="ACHY1N_001393"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(15354..15356),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HFS4043727.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSAS
                     EIRQAARMYAQAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRAAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGE
                     HEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLREAALA"
     gene            complement(15971..17437)
                     /gene="mdtP"
                     /locus_tag="ACHY1N_001394"
     CDS             complement(15971..17437)
                     /gene="mdtP"
                     /locus_tag="ACHY1N_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdtP"
                     /protein_id="HFS4043728.1"
                     /translation="MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKL
                     ADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLSGSHTLAEAKLREEKAQSQADLLDA
                     GSQLQVAALGMLNRQRVSANGFLSPYAMDAPALGMDGPYYTEATVGLFAGLDLDLWGV
                     HRSAVAAAIGAHNAALAETAAVELSLTTGVAQLYYSMQASYQMLDLLEQTRDVIDYAV
                     KAHQSKVAHGLEAQVPFHGARAQILAVDKQIAAVKGQITETRESLRALIGAGASDMPE
                     IKPVALPRVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAF
                     FGLDAIHLDTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVL
                     NAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPV
                     LAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAAPVVEKK"
     gene            complement(17434..19485)
                     /gene="mdtO"
                     /locus_tag="ACHY1N_001395"
     CDS             complement(17434..19485)
                     /gene="mdtO"
                     /locus_tag="ACHY1N_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter permease subunit
                     MdtO"
                     /protein_id="HFS4043729.1"
                     /translation="MSALNSLPLPVVRLLAFFHEELSERRPGRVPQIVQLWVGCLLVI
                     LISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEP
                     LIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCI
                     VVGLYPTLLMTLIGVLWFPSRAITQMHQALNDRLDDAISHLTDSLAPLPETRIEREAL
                     ALQKLNVFCLADDANWRTQSAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKL
                     ASEINKLQHAVAEGQCWQSDWRITESEAMAARECNLENICQTLLQLGQMDPNTPPTPA
                     AKPPSMVADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVG
                     SSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERS
                     SYIGTQMVVTFALATLENVFGPVYDLVEVRDRAMGIIIGTVVSAVIYTFVWPESEART
                     LPQKLAGTLGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVALERQLD
                     SEERALLIERSQTVIRQGRDILHAWDATWNSAQALDNALQPDRAAQFADALEKYAAGL
                     ATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPATEQAQGAT
                     Q"
     gene            complement(19485..20516)
                     /gene="mdtN"
                     /locus_tag="ACHY1N_001396"
     CDS             complement(19485..20516)
                     /gene="mdtN"
                     /locus_tag="ACHY1N_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter periplasmic adaptor
                     subunit MdtN"
                     /protein_id="HFS4043730.1"
                     /translation="MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYA
                     SADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQI
                     MLTQRSVDAQQFGADSINATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
                     QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGR
                     VISLKTSVGQFASAMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKT
                     FEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGA
                     SAVANLEPQ"
     gene            complement(20535..20810)
                     /gene="ytcA"
                     /locus_tag="ACHY1N_001397"
     CDS             complement(20535..20810)
                     /gene="ytcA"
                     /locus_tag="ACHY1N_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtcA family lipoprotein"
                     /protein_id="HFS4043731.1"
                     /translation="MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPSWF
                     FCAIASLILMLITRRVIQRANINLAFVGIIYTALFALYAMLFWLAFF"
     gene            complement(21019..23004)
                     /gene="yjcS"
                     /locus_tag="ACHY1N_001398"
     CDS             complement(21019..23004)
                     /gene="yjcS"
                     /locus_tag="ACHY1N_001398"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl sulfatase YjcS"
                     /protein_id="HFS4043732.1"
                     /translation="MNNSRLFRLSKIIIALTAASGMMVNTAYATDEAKAATQYTQQVN
                     QNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDANGKPYYRGEDYKFDINAPAPETV
                     NPSLWRQSQLNGISGLFKVTDRMYQVRGQDISNITFIEGDTGIIVIDPLVTPPSAKAA
                     LDLYFQNRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISE
                     NVLAGNIMSRRALYSYGLLLAHNPQGNIGNGLGVTLASGYPSIIAPNKTITKTGEKMI
                     IDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFYTLRGAKTRDTSKWT
                     EYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTIKYIHDQTLHLANQGYT
                     MNEIGDMIKLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMG
                     KRYVQALGGSARVINLAQEANKQGDYRWSAELLKQVIAANPGDQVAKNLQANNFEQLG
                     YQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMSVRLDSAKA
                     AGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQSQADASFYISREDLHAVLTGQAKMA
                     DLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTPN"
     gene            complement(23277..24206)
                     /gene="alsK"
                     /locus_tag="ACHY1N_001399"
     CDS             complement(23277..24206)
                     /gene="alsK"
                     /locus_tag="ACHY1N_001399"
                     /EC_number="2.7.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0019316 - D-allose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="allose kinase"
                     /protein_id="HFS4043733.1"
                     /translation="MQKQHNVVAGVDMGATHIRFCLRTAEGETLHCEKKRTAEVIAPG
                     LVSGIGEMIDEQLRRFNARCHGLVMGFPALVSKDKRTIISTPNLPLTAADLYDLADKL
                     ENTLNCPVEFSRDVNLQLSWDVVENRLTQQLVLAAYLGTGMGFAVWMNGAPWTGAHGV
                     AGELGHIPLGDMTQHCACGNPGCLETNCSGMALRRWYEQQPRNYPLSDLFVHAENAPF
                     VQSLLENAARAIATSINLFDPDAVILGGGVMDMPAFPRETLIAMTQKYLRRPLPHQVV
                     RFIAASSSDFNGAQGAAILAHQHFLPQSCAKAP"
     gene            complement(24190..24885)
                     /gene="alsE"
                     /locus_tag="ACHY1N_001400"
     CDS             complement(24190..24885)
                     /gene="alsE"
                     /locus_tag="ACHY1N_001400"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allulose-6-phosphate 3-epimerase"
                     /protein_id="HFS4043734.1"
                     /translation="MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTL
                     SPFFVSQVKKLATKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEI
                     RCHDMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAW
                     REREGLEYEIEVDGSCNKATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTTQIL
                     AAKSEVQPHAKTA"
     gene            complement(24896..25876)
                     /gene="alsC"
                     /locus_tag="ACHY1N_001401"
     CDS             complement(24896..25876)
                     /gene="alsC"
                     /locus_tag="ACHY1N_001401"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter permease"
                     /protein_id="HFS4043735.1"
                     /translation="MGFTTRVKSEASEKKPFNFALFWDKYGTFFILAIIVAIFGSLSP
                     EYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGV
                     DPFLAAMIGGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYG
                     FSFDFVNFFAASVIGIPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGI
                     DVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGK
                     GRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALDRLISK"
     gene            complement(25855..27386)
                     /gene="alsA"
                     /locus_tag="ACHY1N_001402"
                     /pseudo
     CDS             complement(25855..27386)
                     /gene="alsA"
                     /locus_tag="ACHY1N_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418511.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter ATP-binding protein
                     AlsA"
     gene            complement(27513..28448)
                     /gene="alsB"
                     /locus_tag="ACHY1N_001403"
     CDS             complement(27513..28448)
                     /gene="alsB"
                     /locus_tag="ACHY1N_001403"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose transporter substrate-binding protein"
                     /protein_id="HFS4043736.1"
                     /translation="MNKYLKYFSGTLVGLMLSTSAFAAAEYAVVLKTLSNPFWVDMKK
                     GIEDEAKTLGVSVDIFASPSEGDFQSQLQLFEDLSNKNYKGIAFAPLSSVNLVMPVAR
                     AWKKGIYLVNLDEKIDMDNLKKAGGNVEAFVTTDNVAVGAKGASFIIDKLGAEGGEVA
                     IIEGKAGNASGEARRNGATEAFKKASQIKLVASQPADWDRIKALDVATNVLQRNPNIK
                     AIYCANDTMAMGVAQAVANAGKTGKILVVGTDGIPEARKMVEAGQMTATVAQNPADIG
                     ATGLKLMVNAEKSGKVIPLDKAPEFKLVDSILVTQ"
     gene            complement(28507..29397)
                     /gene="alsR"
                     /locus_tag="ACHY1N_001404"
     CDS             complement(28507..29397)
                     /gene="alsR"
                     /locus_tag="ACHY1N_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418513.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose utilization transcriptional regulator
                     AlsR"
                     /protein_id="HFS4043737.1"
                     /translation="MSQSEFDSALPNGIGLAPYLRMKQEGMTENESRIVEWLLKPGNL
                     SCAPAIKDVAEALSVSEAMIVKVSKLLGFSGFRNLRSALEDYFSQSEQVLPSELAFDE
                     APQDVVNKVFNITLRTIMEGQSIVNVDEIHRAARFFYQARQRDLYGAGGSNAICADVQ
                     HKFLRIGVRCQAYPDAHIMMMSASLLQEGDVVLVVTHSGRTSDVKAAVELAKKNGAKI
                     ICITHSYHSPIAKLADYIICSPAPETPLLGRNASARILQLTLLDAFFVSVAQLNIEQA
                     NINMQKTGAIVDFFSPGALK"
     gene            29756..30205
                     /gene="rpiB"
                     /locus_tag="ACHY1N_001405"
                     /gene_synonym="alsI"
     CDS             29756..30205
                     /gene="rpiB"
                     /locus_tag="ACHY1N_001405"
                     /gene_synonym="alsI"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional allose-6-phosphate
                     isomerase/ribose-5-phosphate isomerase RpiB"
                     /protein_id="HFS4043738.1"
                     /translation="MKKIAFGCDHVGFILKHEIVAHLVERGVEVIDKGTWSSERTDYP
                     HYASQVALAVAGGEVDGGILICGTGVGISIAANKFAGIRAVVCSEPYSAQLSRQHNDT
                     NVLAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITAIEQWRN"
     gene            30274..30603
                     /gene="yjdP"
                     /locus_tag="ACHY1N_001406"
     CDS             30274..30603
                     /gene="yjdP"
                     /locus_tag="ACHY1N_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDRRRQL repeat protein YjdP"
                     /protein_id="HFS4043739.1"
                     /translation="MKRFPLFLLFTLLTLSTVPAQADIIDDTIGNIQQAINDAYNPDR
                     GRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRRQLDDRQRQLDQERRQLEDEERR
                     MEDEYGR"
     gene            complement(30750..31508)
                     /gene="phnP"
                     /locus_tag="ACHY1N_001407"
     CDS             complement(30750..31508)
                     /gene="phnP"
                     /locus_tag="ACHY1N_001407"
                     /EC_number="3.1.4.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnP"
                     /protein_id="HFS4043740.1"
                     /translation="MSLTLTLTGTGGAQGVPAWGCECAACDRARRSPQYRRQPCSGVV
                     KFNDAITLIDAGLHDLADRWSPGSFQQFLLTHYHMDHVQGLFPLRWGVGDPIPVYGPP
                     DDQGCDDLFKHPGLLDFSHTVEPFVVFDLQGLQVTPLPLNHSKLTFGYLLETAHSRVA
                     WLSDTAGLPEKTQKFLLNNHPQVMVIDCSHPPREDAPRNHCDLNTVLALNQVIHSPRV
                     ILTHISHQFDAWLMENALPPGFEAGFDGMEIGVA"
     gene            complement(31510..31944)
                     /gene="phnO"
                     /locus_tag="ACHY1N_001408"
     CDS             complement(31510..31944)
                     /gene="phnO"
                     /locus_tag="ACHY1N_001408"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HFS4043741.1"
                     /translation="MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRD
                     PNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAE
                     EEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL"
     gene            complement(31931..32488)
                     /gene="phnN"
                     /locus_tag="ACHY1N_001409"
     CDS             complement(31931..32488)
                     /gene="phnN"
                     /locus_tag="ACHY1N_001409"
                     /EC_number="2.7.4.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033863 - ribose 1,5-bisphosphate
                     phosphokinase activity [Evidence IEA];
                     GO_process: GO:0006015 - 5-phosphoribose 1-diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphokinase"
                     /protein_id="HFS4043742.1"
                     /translation="MMGKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASA
                     GSENHIALSEQEFFTRAGQNLLALSWHANGLYYGVGVEIDLWLHAGFDVLVNGSRAHL
                     PQARARYQSALLPICLQVSPEILRQRLENRGRENASEINARLARAARYTPQDCHTLNN
                     DGSLRQSVDTLLTLIHQKEKHHACL"
     gene            complement(32488..33624)
                     /gene="phnM"
                     /locus_tag="ACHY1N_001410"
     CDS             complement(32488..33624)
                     /gene="phnM"
                     /locus_tag="ACHY1N_001410"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HFS4043743.1"
                     /translation="MIINNVKLVLENEVVHGSLEVQDGEIRAFAESQSRLPEAMDGEG
                     GWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSHDALMVASGITTVLDAVAIGDVR
                     DGGDRLENLEKMINAIEETQKRGVNRAEHRLHLRCELPHHTTLPLFEKLVQREPVTLV
                     SLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRETIAAL
                     CRVRQIALASHDDATHAHVAESHQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVR
                     GGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDESNRFTLPQAVKLVTKN
                     PAQALNLQDRGVIGEGKRADLVLAHRKGNHIHIDHVWRQGKRVF"
     gene            complement(33621..34301)
                     /gene="phnL"
                     /locus_tag="ACHY1N_001411"
     CDS             complement(33621..34301)
                     /gene="phnL"
                     /locus_tag="ACHY1N_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018835 - carbon phosphorus lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HFS4043744.1"
                     /translation="MINVQNVSKTFILHQQNGVRLPVLNRASLTVNAGECVVLHGHSG
                     SGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVI
                     PRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNI
                     ARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKTRGAAIVGIFHDEAVRNDVADR
                     LHPMGASS"
     gene            complement(34412..35170)
                     /gene="phnK"
                     /locus_tag="ACHY1N_001412"
     CDS             complement(34412..35170)
                     /gene="phnK"
                     /locus_tag="ACHY1N_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018835 - carbon phosphorus lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnK"
                     /protein_id="HFS4043745.1"
                     /translation="MNKPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGK
                     TTLLKSISARLTPQQGEIHYENRSLYAMSEADRRRLLRTEWGVVHQHPLDGLRRQVSA
                     GGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
                     VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLV
                     MKQGQVVESGLTDRVLDDPHHPYTQLLVSSVLQN"
     gene            complement(35167..36012)
                     /gene="phnJ"
                     /locus_tag="ACHY1N_001413"
     CDS             complement(35167..36012)
                     /gene="phnJ"
                     /locus_tag="ACHY1N_001413"
                     /EC_number="4.7.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HFS4043746.1"
                     /translation="MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPM
                     PYGWGTGGIQLTASVIGESDVLKVIDQGADDTTNAVSIRNFFKRVTGVNTTERTDDAT
                     LIQTRHRIPETPLTEDQIIIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYED
                     IARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPP
                     FTRVESLDFDDHPFTVQQWDEPCAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQS
                     EAKSQ"
     gene            complement(36005..37069)
                     /gene="phnI"
                     /locus_tag="ACHY1N_001414"
     CDS             complement(36005..37069)
                     /gene="phnI"
                     /locus_tag="ACHY1N_001414"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate synthase subunit PhnI"
                     /protein_id="HFS4043747.1"
                     /translation="MYVAVKGGEKAIDAAHALQESRRRGDTDLPELSVAQIEQQLNLA
                     VDRVMTEGGIADRELAALALKQASGDNVEAIFLLRAYRTTLAKLAVSEPLDTTEMRLE
                     RRISAVYKDIPGGQLLGPTYDYTHRLLDFTLLANGEAPTLTTADSEQQPSPHVFSLLA
                     RQGLAKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRN
                     HPFAGEIRSGYIDVSIVPEELGFAVNVGELLMTECEMVNGFIDPPDEPPHFTRGYGLV
                     FGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNVEAAGFVSHLKLPHY
                     VDFQAELELLKRLQQEQNHG"
     gene            complement(37069..37653)
                     /gene="phnH"
                     /locus_tag="ACHY1N_001415"
     CDS             complement(37069..37653)
                     /gene="phnH"
                     /locus_tag="ACHY1N_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HFS4043748.1"
                     /translation="MTLETAFMLPVQDAQHSFRRLLKAMSEPGVIVALHQLKRGWQPL
                     NIATTSVLLTLADNDTPVWLAAPLSNDIVSQSLRFHTNAPLVSQPEQATFAVTDEAIS
                     SEQLNALSTGTAVAPEAGATLILQVASLSGGRMLRLTGAGIAEERMIAPQLPECILHE
                     LTERPHPFPLGIDLILTCGERLLAIPRTTHVEVC"
     gene            complement(37650..38102)
                     /gene="phnG"
                     /locus_tag="ACHY1N_001416"
     CDS             complement(37650..38102)
                     /gene="phnG"
                     /locus_tag="ACHY1N_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA];
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HFS4043749.1"
                     /translation="MHADTATRQHWMSVLAHSQPAELAARLKALNITADYEVIRAAET
                     GLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLGYSWVLGRDKQHAERCALIDALM
                     QQSRYFQNLSETLIAPLDADRMARIAARQAEVNASRVDFFTMVRGDNA"
     gene            complement(38103..38828)
                     /gene="phnF"
                     /locus_tag="ACHY1N_001417"
     CDS             complement(38103..38828)
                     /gene="phnF"
                     /locus_tag="ACHY1N_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism transcriptional regulator
                     PhnF"
                     /protein_id="HFS4043750.1"
                     /translation="MHLSTHPTSYPTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAAR
                     FEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPFDYPLNAQARFSQNLLDQGSHPT
                     SEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTLWPTLQ
                     RFDSGSLHDFLREQTGIALRRSQTRISARRAQAKECQRLEIPNMSPLLCVRTLNHRDG
                     ESSPAEYSVSLTRADMIEFTMEH"
     gene            complement(38849..39628)
                     /gene="phnE"
                     /locus_tag="ACHY1N_001418"
     CDS             complement(38849..39628)
                     /gene="phnE"
                     /locus_tag="ACHY1N_001418"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313113.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HFS4043751.1"
                     /translation="MQTITIAPPKRSWFSLLSWAVVLAVLVVSWQGAEMAPLTLIKDG
                     GNMATFAADFFPPDFSQWQDYLTEMAVTLQIAVWGTALAVVLSIPFGLMSAENLVPWW
                     VYQPVRRLMDACRAINEMVFAMLFVVAVGLGPFAGVLALFIHTTGVLSKLLSEAVEAI
                     EPGPVEGIRATGANKLEEILYGVLPQVMPLLISYSLYRFESNVRSATVVGMVGAGGIG
                     VTLWEAIRGFQFQQTCALMVLIIVTVSLLDFLSQRLRKHFI"
     gene            complement(39734..40750)
                     /gene="phnD"
                     /locus_tag="ACHY1N_001419"
     CDS             complement(39734..40750)
                     /gene="phnD"
                     /locus_tag="ACHY1N_001419"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4043752.1"
                     /translation="MNAKIIASLAFTSMFSLSTLLSPAHAEEQEKALNFGIISTESQQ
                     NLKPQWTPFLQDMEKKLGVKVNAFFAPDYAGIIQGMRFNKVDIAWYGNLSAMEAVDRA
                     NGQVFAQTVAADGSPGYWSVLIVNKDSPINNLNDLLAKRKDLTFGNGDPNSTSGFLVP
                     GYYVFAKNNISASDFKRTVNAGHETNALAVANKQVDVATNNTENLDKLKTSAPEKLKE
                     LKVIWKSPLIPGDPIVWRKNLSETTKDKIYDFFMNYGKTPEEKAVLERLGWAPFRASS
                     DLQLVPIRQLALFKEMQGVKSNKGLNEQDKLAKTTEIQAQLDDLDRLNNALSAMSSVS
                     KAVQ"
     gene            complement(40775..41563)
                     /gene="phnC"
                     /locus_tag="ACHY1N_001420"
     CDS             complement(40775..41563)
                     /gene="phnC"
                     /locus_tag="ACHY1N_001420"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HFS4043753.1"
                     /translation="MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKS
                     TLLRHLSGLITGDKSAGSHIELLGRTVQREGRLARDIRKSRANTGYIFQQFNLVNRLS
                     VLENVLIGALGSTPFWRTCFSWFTGEQKQRALQALTRVGMVHFAHQRVSTLSGGQQQR
                     VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALR
                     YCERIVALRQGHVFYDGSSQQFDNERFDHLYRSINRIEENAKAA"
     gene            complement(41696..42139)
                     /gene="yjdN"
                     /locus_tag="ACHY1N_001421"
     CDS             complement(41696..42139)
                     /gene="yjdN"
                     /locus_tag="ACHY1N_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
                     /protein_id="HFS4043754.1"
                     /translation="MPLSPYLSFAGNCADAIAYYQRTLGAELLYKISFGEMPKSAQDS
                     AENCPSGMQFPDTAIAHANVRIAGSDIMMSDAIPSGKASYSGFTLVLDSQQVEEGKRW
                     FDNLAANGKIEMAWQETFWAHGFGKVTDKFGVPWMINVVKQQPTQ"
     gene            complement(42299..42634)
                     /gene="yjdM"
                     /locus_tag="ACHY1N_001422"
     CDS             complement(42299..42634)
                     /gene="yjdM"
                     /locus_tag="ACHY1N_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFS4043755.1"
                     /translation="MSLPHCPKCNSEYTYEDNGMYICPECAYEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIIKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
     gene            43035..45263
                     /gene="crfC"
                     /locus_tag="ACHY1N_001423"
     CDS             43035..45263
                     /gene="crfC"
                     /locus_tag="ACHY1N_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="clamp-binding protein CrfC"
                     /protein_id="HFS4043756.1"
                     /translation="MYTQTLYELSQEAERLLQLSRQQLQLLEKMPLSVPGDDAPQLAL
                     PWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPM
                     TALPTLIRHTPGQKEPVLHFSHVAPIDCLIQQLQQRLRDCDIKHLTDVLEIDKDMRAL
                     MQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVE
                     FVHLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLNQQLARASAVLAVLDYTQLKSISD
                     EEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKGCITPQQIFPVS
                     SMWGYLANRARHELANNGKLPAPEQQRWVEDFAHAALGRRWRHADLADLEHIRHAADQ
                     LWEDSLFAQPIQALLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGLNVACEQ
                     LRQNIHQVEESLQLLQLNQAQVSGEIKHEIELALTSANHFLRQQQDALNAQLAALFQD
                     DSEPLSEMRTRCETLLQTAQNTISRDFTLRFAELESTLCRVLTDVIRPIEQQVKMELS
                     ESGFRPGFHFPVFHGVVPHFNTRQLFSAVISRQDATDEQSTRLGVVRETFSRWLNQPD
                     WGRGNEKSPTETVDYSVLQRALSAEVDLYCQQMAKVLAEQVDESVTAGMNTFFAEFAS
                     CLTELQTRLRESLALRQQNESVVRLMQQQLQQTVMTHGWIYTDAQLLRDDIQTLFTAE
                     RY"
     gene            45260..46138
                     /gene="rdcB"
                     /locus_tag="ACHY1N_001424"
     CDS             45260..46138
                     /gene="rdcB"
                     /locus_tag="ACHY1N_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418534.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcZ-like family protein"
                     /protein_id="HFS4043757.1"
                     /translation="MTKTLLDGPGRVLESVYPRFLVDLAQGDDARLPQAHQQQFRERL
                     MQELLSRVQLQTWTNGGMLNAPLSLRLTMVEKLASMLDPGHLALTQIAQHLALLQKMD
                     HRKHSAFPELPQQIAALYEWFSARCRWKEKALTQRGLLVQAGEQSEQIFTRWRAGAYN
                     AWSLPGRCFIVLEELRWGVFGDACRLGSPQAVALLLGDLRVKATQHLAESINAAPTTR
                     HYYHQWFASSTVPTGGDHADFLSWLGKWTTADKQPVCWSVTQRWQTVALGMPRLCSAQ
                     RLAGAMVEEIFSVNLA"
     gene            46402..47904
                     /gene="proP"
                     /locus_tag="ACHY1N_001425"
     CDS             46402..47904
                     /gene="proP"
                     /locus_tag="ACHY1N_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="HFS4043758.1"
                     /translation="MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRSLLTCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVA
                     LFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVIGLITGVTMKETANRPLKGAT
                     PAASDIQEAKEILVEHYDNIEQKIDNIDHEIADLQAKRTRLVQQHPRIDE"
     gene            48016..48105
                     /gene="pmrR"
                     /locus_tag="ACHY1N_001426"
     CDS             48016..48105
                     /gene="pmrR"
                     /locus_tag="ACHY1N_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HFS4043759.1"
                     /translation="MKNRVYESLTTVFSVLVVSSFLYIWFATF"
     gene            complement(48081..49181)
                     /gene="pmrB"
                     /locus_tag="ACHY1N_001427"
     CDS             complement(48081..49181)
                     /gene="pmrB"
                     /locus_tag="ACHY1N_001427"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HFS4043760.1"
                     /translation="MNLMHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQI
                     QLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQ
                     KELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
                     LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLE
                     DVILPSYDELSTMLDQRQQTLLLPESAADITVQGDATLLRMLLRNLVENAHRYSPQGS
                     NIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQL
                     HHGQFFLQNRQETSGTRAWVRLKKDQNVANQI"
     gene            complement(49182..49850)
                     /gene="basR"
                     /locus_tag="ACHY1N_001428"
     CDS             complement(49182..49850)
                     /gene="basR"
                     /locus_tag="ACHY1N_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BasR"
                     /protein_id="HFS4043761.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGH
                     YSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVA
                     NEEN"
     gene            complement(49847..51490)
                     /gene="eptA"
                     /locus_tag="ACHY1N_001429"
     CDS             complement(49847..51490)
                     /gene="eptA"
                     /locus_tag="ACHY1N_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HFS4043762.1"
                     /translation="MLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDS
                     LHNVLVFLSMPVVAFSVINIVLTLSSFLWLNRPLACLFILVGAAAQYFIMTYGIVIDR
                     SMIANIIDTTPAESYALMTPQMLLTLGFSGVLAALIACWIKIKPATSRLRSVLFRGAN
                     ILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVR
                     IGEDAHRNPLMQNEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTA
                     SCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGACD
                     RVPHQNVTALNLPGQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYYNR
                     YPPQFRKFTPTCDTNEIQTCSKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSL
                     VYLSDHGESLGENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQ
                     TQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE"
     gene            complement(51594..52931)
                     /gene="adiC"
                     /locus_tag="ACHY1N_001430"
     CDS             complement(51594..52931)
                     /gene="adiC"
                     /locus_tag="ACHY1N_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HFS4043763.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIY
                     GWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALI
                     PIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILM
                     TIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTT
                     IAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD"
     gene            complement(53068..53829)
                     /gene="adiY"
                     /locus_tag="ACHY1N_001431"
     CDS             complement(53068..53829)
                     /gene="adiY"
                     /locus_tag="ACHY1N_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator AdiY"
                     /protein_id="HFS4043764.1"
                     /translation="MRICSDQPCIVLLTEKDVWIRVNGKEPISLKANHMALLNCENNI
                     IDVSSLNNTLVAHISHDIIKDYLRFLNKDLSQIPVWQRSATPILTLPCLTPDVFRVAA
                     QHSMMPAETESEKERTRALLFTVLSRFLDSKKFLSLMMYMLRNCVSDSVYQIIESDIH
                     KDWNLSMVASCLCLSPSLLKKKLKSENTSYSQIITTCRMRYAVNELMMDGKNISQVSQ
                     SCGYNSTSYFISVFKDFYGMTPLHYVSQHRERTVA"
     gene            complement(54154..56421)
                     /gene="adiA"
                     /locus_tag="ACHY1N_001432"
     CDS             complement(54154..56421)
                     /gene="adiA"
                     /locus_tag="ACHY1N_001432"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418541.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HFS4043765.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     FAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQ
                     DLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYDFADAPTKLLTTVQD
                     CWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPD
                     TYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPVAEVTPREAYNAIVDNNVELVSI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSYLRSLQSWDHHFPGFEHETEG
                     TEIIDGIYHVMCVKA"
     gene            complement(56620..57528)
                     /gene="melR"
                     /locus_tag="ACHY1N_001433"
     CDS             complement(56620..57528)
                     /gene="melR"
                     /locus_tag="ACHY1N_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HFS4043766.1"
                     /translation="MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWH
                     GQVEVNVPFDGDVEYLINNEKVNINQGHITLFWACTPHQLTDTGTCQSMAIFNLPMHL
                     FLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLM
                     LKRFSLSGWEPILVNKTSRAHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVK
                     LNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYS
                     TFGKYVGMSPQQYRKLSQQRRQTFPG"
     gene            57811..59166
                     /gene="melA"
                     /locus_tag="ACHY1N_001434"
     CDS             57811..59166
                     /gene="melA"
                     /locus_tag="ACHY1N_001434"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFS4043767.1"
                     /translation="MMTAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPT
                     RLEESHIVVRKLMDSAGASGKITCHTQQKEALQDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGS
                     YVNLYPELLAAYEAGQAPKPNIHGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEEYKNASRIDIKPSREYASTIMNA
                     IWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKVGTLPSHLAALMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLH
                     R"
     gene            59269..60690
                     /gene="melB"
                     /locus_tag="ACHY1N_001435"
     CDS             59269..60690
                     /gene="melB"
                     /locus_tag="ACHY1N_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418544.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="melibiose:sodium transporter MelB"
                     /protein_id="HFS4043768.1"
                     /translation="MSISMTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLV
                     GTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLANSVILFLLFSAHLFEG
                     TTQIVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPYPRFFASLAGFVTA
                     GVTLPFVNYVGGGDRGFGFQMFTLVLIAFFIVSTIITLRNVHEVFSSDNQPSAEGSHL
                     TLKAIVALIYKNDQLSCLLGMALAYNVASNIITGFAIYYFSYVIGDADLFPYYLSYAG
                     AANLVTLVFFPRLVKSLSRRILWAGASILPVLSCGVLLLMALMSYHNVVLIVIAGILL
                     NVGTALFWVLQVIMVADTVDYGEYKLHVRCESIAYSVQTMVVKGGSAFAAFFIAVVLG
                     MIGYVPNVEQSTQALLGMQFIMIALPTLFFMVTLILYFRFYRLNGDTLRRIQIHLLDK
                     YRKVPPEPVHADIPVGAVSDVKA"
     gene            complement(60829..61458)
                     /gene="yjdF"
                     /locus_tag="ACHY1N_001436"
     CDS             complement(60829..61458)
                     /gene="yjdF"
                     /locus_tag="ACHY1N_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HFS4043769.1"
                     /translation="MTRTLKPLILNTGALALTLILIYTGISAHDKLTWLMEVTPVIIV
                     VPLLLATAKRYPLTPLLYTLIFFHAIILMVGGQYTYAKVPIGFEVQEWLGLSRNPYDK
                     LGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWWAALAMGQ
                     GADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITG"
     gene            complement(61581..63227)
                     /gene="fumB"
                     /locus_tag="ACHY1N_001437"
     CDS             complement(61581..63227)
                     /gene="fumB"
                     /locus_tag="ACHY1N_001437"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HFS4043770.1"
                     /translation="MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEP
                     EALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAHYYDELPTEGNEHGQAFRDVQLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVG
                     RDIAHAKLKELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVNKQCANCTK"
     gene            complement(63305..64645)
                     /gene="dcuB"
                     /locus_tag="ACHY1N_001438"
     CDS             complement(63305..64645)
                     /gene="dcuB"
                     /locus_tag="ACHY1N_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuB"
                     /protein_id="HFS4043771.1"
                     /translation="MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREY
                     VYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     PTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            complement(65216..65935)
                     /gene="dcuR"
                     /locus_tag="ACHY1N_001439"
     CDS             complement(65216..65935)
                     /gene="dcuR"
                     /locus_tag="ACHY1N_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HFS4043772.1"
                     /translation="MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIF
                     NSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLT
                     PQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRIQAEHYSLLKQYCQ"
     gene            complement(65932..67563)
                     /gene="dcuS"
                     /locus_tag="ACHY1N_001440"
     CDS             complement(65932..67563)
                     /gene="dcuS"
                     /locus_tag="ACHY1N_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4043773.1"
                     /translation="MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQI
                     SDMTRDGLANKALAVARTLADSPEIRQGLQKKPQESGIQAIAEAVRKRNDLLFIVVTD
                     MQSLRYSHPEAQRIGQPFKGDDILKALNGKENVAINRGFLAQALRVFTPIYDENHKQI
                     GVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQV
                     VDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRL
                     DGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKI
                     KSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEAL
                     GPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVK
                     QQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR"
     gene            67744..67974
                     /gene="yjdI"
                     /locus_tag="ACHY1N_001441"
     CDS             67744..67974
                     /gene="yjdI"
                     /locus_tag="ACHY1N_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S mono-cluster protein YjdI"
                     /protein_id="HFS4043774.1"
                     /translation="MDQALLDEGYRCYTGEKIDVYFNTAICQHSGNCVRGNGKLFNLK
                     RKPWIMPDEVDVVTVVKVIDTCPSGALKYRHK"
     gene            67986..68258
                     /gene="yjdJ"
                     /locus_tag="ACHY1N_001442"
     CDS             67986..68258
                     /gene="yjdJ"
                     /locus_tag="ACHY1N_001442"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4043775.1"
                     /translation="MEIREGHNKFYINDEQGKQIAEIVFVPTGENLAIIEHTDVDESL
                     KGQGIGKQLVAKVVEKMRREKRKIIPLCPFAKHEFDKTREYDDIRS"
     gene            68485..68781
                     /gene="ghoS"
                     /locus_tag="ACHY1N_001443"
     CDS             68485..68781
                     /gene="ghoS"
                     /locus_tag="ACHY1N_001443"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HFS4043776.1"
                     /translation="MEGKNKFNTYVVSFDYPSSYSSVFLRLRSLMYDMNFSSIVADEY
                     GIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLNIMTVDDYFRQFYK"
     gene            68809..68982
                     /gene="ghoT"
                     /locus_tag="ACHY1N_001444"
     CDS             68809..68982
                     /gene="ghoT"
                     /locus_tag="ACHY1N_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system toxin GhoT"
                     /protein_id="HFS4043777.1"
                     /translation="MALFSKILIFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITW
                     PMSLPVALLFSLF"
     gene            complement(69101..70618)
                     /gene="lysS"
                     /locus_tag="ACHY1N_001445"
     CDS             complement(69101..70618)
                     /gene="lysS"
                     /locus_tag="ACHY1N_001445"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFS4043778.1"
                     /translation="MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDH
                     TSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     SLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG
                     DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK"
     gene            complement(70855..72312)
                     /gene="dtpC"
                     /locus_tag="ACHY1N_001446"
     CDS             complement(70855..72312)
                     /gene="dtpC"
                     /locus_tag="ACHY1N_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpC"
                     /protein_id="HFS4043779.1"
                     /translation="MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDN
                     HAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL
                     YLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
                     AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVM
                     LCLAPVFFTLLLENDWSGYLLAIVCLIAAQIIARMMVKFPEHRRALWQIVLLMFVGTL
                     FWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVMLAGVVLAWLASPESR
                     GNSTLRVWLKFAFGLLLMACGFMLLAFDARHAAADGQASMGVMISGLALMGFAELFID
                     PVAIAQITRLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQ
                     MGEWTLACVAIIVVLAFATRFLFSTPTNMIQESND"
     gene            complement(72371..74518)
                     /gene="cadA"
                     /locus_tag="ACHY1N_001447"
     CDS             complement(72371..74518)
                     /gene="cadA"
                     /locus_tag="ACHY1N_001447"
                     /EC_number="4.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase CadA"
                     /protein_id="HFS4043780.1"
                     /translation="MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLK
                     LIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISF
                     FEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
                     SPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTN
                     GTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIP
                     QSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWV
                     PYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEA
                     YMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWF
                     FDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFG
                     IPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRV
                     KNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAF
                     QKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEI
                     GAHYPGFETDIHGAYRQADGRYTVKVLKEESKK"
     gene            complement(74598..75932)
                     /gene="cadB"
                     /locus_tag="ACHY1N_001448"
     CDS             complement(74598..75932)
                     /gene="cadB"
                     /locus_tag="ACHY1N_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043872 - lysine:cadaverine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cadaverine/lysine antiporter"
                     /protein_id="HFS4043781.1"
                     /translation="MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWI
                     ISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGI
                     TAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVM
                     TAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKR
                     TVPLATMLGTGLAGIVYIAATQVLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSA
                     FTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPKKGLLLAAVKMTALM
                     ILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVL
                     GCVFCFIALMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH"
BASE COUNT        17872 a        19427 c        20218 g        18655 t
ORIGIN      
        1 atctggcaaa gaggaaaaaa catattattt aaaccattat agcgcataaa atatccttat
       61 aattaacaag aaacaaaagg catattctct gcattatcat tttctacgac tgtcaaaaat
      121 cgctcatttt ttaatgagtt tatttgttta atattatggg aaaaggtgat gcatgttgga
      181 gaggaagagt attccccggt caggcgaccg gggaagggga gagattaatg tgcgcggcct
      241 tgctcaacgc caaagccggt ctgggagcgg ataaactgtg cacggaacag ttcacgctcg
      301 cgcgcacctt ccgctgagtt atcggttgcc gagaagaacc agatgccgag gaatgccacg
      361 ctgatagaga acagcgccgg gtattcatac gggaagatgg ctttttcgtg accaaggatc
      421 tgtacccaaa tcgtcgggcc gaggatcatc agtaccactg cggtaatcag ccccagccag
      481 ccacccatca tcgcgccacg agtggtcagt ttcgaccagt acatagaaag cagaatgatc
      541 gggaagttac agctcgctgc gatggcaaac gccaggccta ccatgaaggc gatgttctga
      601 ttctcaaaca gcacgccgag gataatggca atcacaccta aaatcagcac ggtgattttc
      661 gatacccgca gttcttcacg ttcggtcgcg ccttttttga agacgttagc gtacaggtca
      721 tgcgaaaccg ctgatgcgcc cgccagcgtc agaccagcaa ccaccgcaag aatggtggca
      781 aaagcaaccg ctgaaataaa accgaggaac aggttgccgc ccactgcatt cgccaggtga
      841 acggccgcca tgttgttacc accaatcaga tggcccgccg cgtctttata ttccggattc
      901 gcaccaacca gcatgatcgc gccgaagccg ataataaagg tcagaatata gaagtagccc
      961 ataaacccgg tggcgtagaa cacgctctta cgtgcttcgc gggcatcgct gactgtaaag
     1021 aagcgcatca gaatgtgcgg caagcccgcc gtaccaaaca tcagtcccag acccagagag
     1081 agcgcggaga tcggatcttt caccagcccg cccggcttca tgatgtcgac acctttcggg
     1141 tgtaccgcca tcgcttcact gaacagattg ttgaagctaa agccgacgtg tttcatcacc
     1201 ataaaggcca taaagctggc accgaacagc aacagcacgg ctttgataat ctgtacccaa
     1261 gtggtcgcca gcatgccgcc gaacaggacg tacatcatca tcagcacgcc gaccagcacc
     1321 accgcaatgt gatagttaag gccaaacagc agctcgatca gtttacctgc gcccaccatc
     1381 tgggcgataa ggtaaagcgc caccaccacc agagaaccac aggccgaaag aatacgaatc
     1441 ggcccttgtt tcagacggta agaggccaca tcggcaaagg tgtagcgccc caggttacgc
     1501 agacgttcgg caatcaggaa caaaatgatc ggccagccca ccaggaagcc cagcgagtaa
     1561 attaagccgt catagccgga ggtaaacacc agcgcggaga tccccaagaa tgaggcggcg
     1621 gacatatagt ccccggcaat cgccagcccg ttctggaagc cagtgatatt gccgcctgcg
     1681 gtgtagtagt cgctacgaga acgtacgcgt tttgatgccc agtaggtaat gccgagcgta
     1741 aacacgacga aaatcaggaa cataataatc gcctgccagt tcgttggctg gcgctctacg
     1801 gccccgctaa tagcatccgc ggcgttagct gcgaaaggga gtgtggcggc aagcgccgtc
     1861 agaactcttt tcatgatgct tgtacctcat gcaggacttc attattaaga cggtcgaatt
     1921 cgccgttcgc ccgccagatg tagataccgg tgagaacaaa ggagatcaca atcactccaa
     1981 caccaattgg aataccgcgt gtgacgctgg tgttcggatt cagcggcgtg cccagccagc
     2041 cgggcgcgaa ggcgatcagt aaaataaagc cgatataaac tgccagcata ataatcgaca
     2101 ggatggtggc aaaccgttgc cgtttttcga ctaactccct gaaatgcgca ttgtcttcta
     2161 tccgctgata aatagtgcca ttcatcacag attctccaga ggtaatgtag ggattgtttt
     2221 aattcccgct cccttatggg agaaggttaa cgctcgggta acccttgccg aatgtaggcc
     2281 ggataaggcg tttacgccgc atccggcaat caatgcctga tgcgacgctg tcgcgtctta
     2341 tcaggcctac aaaccgttac cgactcgcat ccggcaattg tgggttacga tggcatcgcg
     2401 atagcctgct tctcttcaag cagcttctcg actacgccag gatcggcaag cgtcgaggta
     2461 tcgcccaggt tgctggtatc gcccgccgca attttgcgca gaatacggcg cataattttg
     2521 ccggagcggg ttttaggcag ggagtcggtc cagtgcagca cgtctggcgt cgccagcggg
     2581 ccaatctctt tacgcaccca gttgcggact tctgcgtaca gttctggtga cggttcctcc
     2641 ccgtgattaa gcgtgacgta ggcgtagatc gcctgacctt taatattgtg cggaatacct
     2701 actacggcgg cttcggcaat cttcggatgc gccaccagcg ccgactcaat ctctgccgtc
     2761 cccagacggt gaccggagac gttcagcacg tcgtccacac gcccggtgat ccagtaatag
     2821 ccatcttcat cgcgacgcgc gccgtcgccg ctgaaataca tatttttgaa ggtggagaag
     2881 taggtctgtt caaaacgttc gtgatcgcca aacagcgtac gcgcctgacc cggccaggag
     2941 tcggtgatca ccaggctgcc ttcggtagcg ccttccagcg ggttaccttc gttatcgacc
     3001 agcgccggtt gcacgccgaa gaacggacgt gttgccgaac cggctttcag ctcggtagcg
     3061 ccaggcagcg gcgtgatcat gaaaccgcca gtttcggtct gccaccaggt atcgaccacc
     3121 ggacatttct cgttgccgat ttttttccag taccactccc acgcttccgg gttaattggc
     3181 tcgcccacgg aaccgagaat gcgcagcgac gaacggtcgg tgccttcgat cgctttatcg
     3241 ccttccgcca tcagcgcgcg gatcgccgtg ggtgcggtat agagaatatt gacctgatgc
     3301 ttgtccacca cctgcgccat acgggcaggc gtcggccagt tgggtacgcc ttcaaacatc
     3361 agcgtggtcg caccgcaggc cagcgggccg tacagcaagt aactgtgtcc ggtcacccag
     3421 cccacatcgg cggtgcacca gtagatatca cccggatgat aatcaaagac atatttaaag
     3481 gtcagcgccg cgtacaccag ataaccgccg gtagtatgca gcacaccttt tggcttaccg
     3541 gtagaaccgg aggtgtagag aataaacagc ggatcttcgg cgttcatctc ttccgcctgg
     3601 tgctgatcgc tcgcttgctc aaccaggtcg tgccaccaca ggtcgcgccc ttcctgccag
     3661 tcaattttcc cgccagtacg cttcagtacc accacatgct ctacgctggt gacgttcggg
     3721 tttttcagcg cgtcatcaac gtttttcttc agcggaatac tgcgcccggc acgcacacct
     3781 tcgtcggaag tgatcaccag tcgtgagttg gaatcaataa tgcgcccggc aacggcttcc
     3841 ggcgagaagc cgccgaaaat caccgaatgc accgcgccaa tgcgggcgca ggccagcatc
     3901 gcaaccgcgg cttccggcac catcggcata taaatcgcca ccacatcacc ttttttaatg
     3961 cccagctcga gcagggtatt ggcgaagcgg cagacgtcgc ggtgcagctc tttatagctg
     4021 atatgtttgc tctggctggc gtcgtcgcct tcccagatga tggcggtgcg atcgccgttt
     4081 tcttgcagat ggcggtcaag gcagtttgcc gccagattca gcgtgccgtc ctcgtaccat
     4141 ttaatggaca cattaccggg ggcaaaggag gtatttttca ccttctggta cggtttgatc
     4201 cagtcgagaa tttttccctg ttcgccccag aaggtatcag gtacgttaat agattgttga
     4261 tacatcgcct cgtactgctg agggtttatc aggcaacggt ctgcgatgtt ggcaggaatg
     4321 gtgtgtttgt gaatttggct catgcttttg ttctccttgt gggatgttaa taatatgtgg
     4381 cataagcgtt aaatgtaggg gtattggcag ttttgtttag tatttgggcg acagatcacg
     4441 caaaagtaga attgtgcaaa taaacggcag ggtaattttt gaaggtcacc aacaaaagtt
     4501 gattaattct ttgaggaaca tgcagttatg catgctgttg aaaaagagga agatactgac
     4561 taactctaaa gtggtatttt acatgcactt acaattgatt aaagacaaca ttcacagtgt
     4621 ggttatttgt tacacatagg ggcgagcaat gtcatgacag tgtaggtgcg gttactgtcg
     4681 tgaaaacaat aaaaaccgcc attgcaacaa tggcgcaatt cggatgaagc ccctatgaca
     4741 aggataaaaa taaacgcacg ccgtatcttc agcttattga ttcctttttt ctttttcact
     4801 tctgttcacg ctgaacaaac ggcagctccc gcaaaacctg taactgtgga agcgaagaat
     4861 gaaacctttg ccccgcagca tcccgatcaa tatctctcct ggaaagccac ctcggaacag
     4921 tcagagcgtg ttgacgccct ggcggaagat ccacggctgg tgatcctgtg ggcggggtat
     4981 cccttctcgc gcgattacaa caagccgcgt ggacatgcct ttgctgtgac cgatgtgcgt
     5041 gaaaccctgc gtaccggtgc gccgaaaaac gctgaagatg gtccgctacc gatggcgtgc
     5101 tggagttgta aaagcccgga tgtggcgcgt ctgatccaga aagacggcga agatggctac
     5161 ttccacggta agtgggcgcg cggcggcccg gaaatcgtca acaacttagg ttgtgccgac
     5221 tgccataaca ccgcctcacc agagttcgcc aaaggcaaac cggagttaac cctttcccgt
     5281 ccgtatgcgg ctcgcgcgat ggaagccatt ggtaaacctt ttgagaaagc cggacgtttc
     5341 gaccagcaat cgatggtttg cggtcagtgc catgtggagt attacttcga cggcaaaaac
     5401 aaagcggtta aattcccgtg ggatgacggc atgaaagtcg aaaatatgga gcagtattac
     5461 gacaaaattg ccttctctga ctggactaac tccctgtcga aaacgccaat gctgaaagcg
     5521 cagcacccgg aatatgaaac ctggacagcg ggcattcacg gtaaaaacaa cgtgacctgt
     5581 atcgactgcc atatgccaaa agtgcagaac gccgaaggca aactctacac cgaccataaa
     5641 attggtaatc cgtttgataa cttcgcccag acttgtgcga actgccatac ccaggacaaa
     5701 gctgccttgc aaaaagtggt cgcggaacgt aagcagtcga ttaacgacct gaaaatcaag
     5761 gttgaagatc aactggttca cgctcacttc gaagcgaaag cagcgctgga tgcaggcgcg
     5821 acggaagccg aaatgaagcc gattcaggac gatatccgtc atgcccagtg gcgttgggat
     5881 ctggcgatcg cttcccacgg cattcatatg cacgcaccgg aagaaggttt acggatgctc
     5941 ggtactgcga tggataaagc ggcggatgca cgcaccaaac tggcgcgcct gctggcgacc
     6001 aaaggcatca cccatgaaat cgagatcccg gatatctcga ccaaagagaa agcccagcag
     6061 gccattggcc tgaacatgga acaaatcaag gccgagaagc aggacttcat caaaacggtg
     6121 atcccgcagt gggaagaaca ggcacgtaaa aatggtctgt taagccaata accccgttcc
     6181 gactcgcaag gggcggaaaa cacaatggag tgaatatgag cgtattacgt tcgttattaa
     6241 ctgctggggt gctggcgtcg ggcctgttgt ggagcctgaa cggaattacc gctacccctg
     6301 cggcgcaggc atctggtgat cgctacgaag ttacccagca gcgtaacccg gatgccgcct
     6361 gtctggactg tcataagcca gatatcgaag gtatgcatgg caaacatgct tccgttatca
     6421 acccgaataa caaactgccg gtcacctgca ccaactgtca cggccagcca tcaccgcaac
     6481 accgcgaagg ggtgaaagat gtgatgcgct ttaacgagcc gatgtacaag gtcggagagc
     6541 agaacagcgt ctgtatgtcc tgtcatctgc cggaacagtt gcaaaaagcg ttctggccgc
     6601 acgatgtcca cgtaaccaaa gtggcgtgcg ccagctgcca ttccctgcat ccacagcaag
     6661 atacgatgca gacgttaagt gacaaaggac ggattaagat ttgcgtcgat tgccacagcg
     6721 atcagcgcac caatccgaac tttaacccgg cgtctgttcc gttgcttaag gagcagccat
     6781 gacctggtct cgtcgccagt ttctcaccgg cgtcggcgtg ctggcagccg tcagcggcac
     6841 cgcagggcgc gtggtggcga aaacgttgaa tatcaatggg gtgcgttacg gcatggtgca
     6901 tgacgagtcg ttatgcatcg gctgtaccgc ctgtatggat gcttgtcggg aagtgaacaa
     6961 ggtgccggaa ggcgtctcgc gcctgatgat tattcgtagc gagccgcagg gcgaatttcc
     7021 tgatgtgaaa tatcgcttct tccgtaagtc ttgccagcac tgcgatcatg cgccgtgcgt
     7081 tgacgtctgc ccgaccggtg cgtcttttcg tgatgccgct agcgggattg tcgatgttaa
     7141 tcctgatctc tgcgtcggtt gtcagtactg catcgccgcc tgtccgtacc gcgtgcgctt
     7201 tatccatccg gtcacgaaga cggcggacaa atgcgatttc tgccgtaaga ccaatttgca
     7261 ggccggtaag ctgcccgcgt gcgttgaggc ttgcccgacg aaggcgctga cgtttggcaa
     7321 tctggacgat cctaacagtg agatttcgca actgctgcgc cagaagccta cttaccgcta
     7381 caagctggcg ctgggaacca aaccgaagct gtaccgcgta ccgtttaaat acggggaggt
     7441 gagccaatga cgcagacttc cgcatttcat tttgaatcgc tggtgtggga ctggccgatt
     7501 gccatctacc tgtttttgat tggtatttct gccggtctgg tgacgctggc cgtgctgtta
     7561 cgtcgcttct acccgcaggc gggcggtgca gacagcacgt tgctgcgcac cacgctgatt
     7621 gtcggacctg gcgcggtgat cctcggtctg ttgatcctcg tcttccacct gacaagaccg
     7681 tggaccttct ggaagctgat gttccactac agttttacct cggtgatgtc gatgggggtg
     7741 atgctgtttc agctctacat ggtggtgctg gtgctgtggc tggcgaaaat ctttgaacat
     7801 gatttgcttg ccctgcaaca acgctggttg ccgaagctgg ggatcgtgca aaaggttctg
     7861 agcctgctga cgcccgttca tcgcggactg gaaacgctga tgctggtgtt ggcggtgctg
     7921 ctgggggctt ataccggctt tctgctgtcg gcgctgaaat cgtatccgtt cctcaataac
     7981 ccgatcctgc cggtgctgtt cctcttctcc ggcatctcgt ccggtgtggc ggtagcgctg
     8041 atcgccatgg cgatacgcca acgcaaaaat ccgcattcca cggaagcgca ctttgttcac
     8101 cgtatggaaa tccccgtggt atggggtgaa atcttcctgc tggtggcgtt ttttgtcggt
     8161 ctggcgctgg gcgatgacgg taaagtgcgt gcgctggtgg cggcattagg tggcggtttc
     8221 tggacgtggt ggttctggct tggtgtcgcc gggctggggc tgattgtgcc aatgttgctc
     8281 aaaccgtggg tcaatcgcag ttccggcatt cctgccgtgt tggcggcgtg tggggccagt
     8341 ctggtcggcg tgttgatgct gcgctttttc attctctacg ccggacagtt gacggtggcg
     8401 taagccagaa aagaggtggt ttctggacgt attccttcct gaagtcggtt ttctggcgtt
     8461 gttgttaagt ctcggggtca acgtgttgac cccgttgacg gcctttgcgg gagtgcggtt
     8521 gcgctggcct gccatgatgc gactcacttg catcggcatt ctggcgcagt tcgcgctcct
     8581 gctgctcgcc tttggcgtac tgacgtattg ttttctcatc agcgatttct cggtcattta
     8641 tgtcgcgcaa catagctata gcctgctgtc gtgggaactc aagctggcag cggtgtgggg
     8701 cggccatgaa ggttcgctgc tgctttgggt gctgctgctt tccgcctgga gcgcgctgtt
     8761 tgcctggcat tatcggcagc aaaccgatcc gctatttccg ctgacgttag ccgttttatc
     8821 tctcatgctc gccgcactgc tactgtttgt ggtgctgtgg tccgatccct tcgtgcggat
     8881 atttccacca gcaatcgaag gccgcgatct caatccgatg ctgcaacatc ccggtcttat
     8941 ctttcatcca ccgctgcttt accttggcta tggcggtttg atggtagcgg cgagcgtggc
     9001 gctggcgagt ttactgcgcg gcgagtttga tggtgcctgc gccagaattt gttggcgctg
     9061 ggcactacct ggctggagcg cattaacggc ggggatcatc ctcggttcct ggtgggccta
     9121 ttgcgaactg ggctggggcg gctggtggtt ctgggatccg gtggaaaacg cctctttatt
     9181 accctggctt tctgccactg cgctgctgca cagtttgtcc ctgacacgcc agcgggagat
     9241 tttccgccac tggtcgctgt tgctggcgat agtaactctg atgctgtcgc tactgggtac
     9301 cttaattgtc cgttctggca ttctggtttc ggttcatgcg ttcgcactgg ataacgtccg
     9361 cgccgtgccg ttgttcagcc tgtttgcact gattagcctt gcgtctctgg ctctgtatgg
     9421 ctggcgagcg cgggacggtg gcccggtggt gcgtttttcg gggttatcgc gggaaatgtt
     9481 aatcctcgct acgctgttgc tgttttgcgc agtgctactg atcgtgctgg tgggaacgct
     9541 ttatccgatg atttacggtc tgctgggctg gggacgcctc tccgttggcg cgccgtattt
     9601 taaccgcgcg acgttaccgt ttggcctgtt gatgctggtg gtgattgtgc tggcgacgtt
     9661 tgtctctggc aaacgcgtgc agcttccggc gctggtagct catgcgggcg tgctgttatt
     9721 tgccgctggg atcgtggttt ccagcgtcag ccgtcaggag atcagcctga atttacagcc
     9781 gggtcagcag gtgacgctgg caggatacac cttccgtttt gagcgcctcg atctgcaagc
     9841 caaaggcaat tacaccagcg aaaaagcgat agtggcactg tttgaccatc agcaacgcat
     9901 tggtgaactg atgccggagc ggcgttttta cgaagcacgt cgtcagcaaa tgatggaacc
     9961 gtcaattcgc tggaacggca tccatgactg gtatgcggtc atgggtgaaa aaaccggagc
    10021 ggatcgttac gcttttcgct tgtatgtaca aagcggtgtg cgctggatct gggggggagg
    10081 attgttgatg attgcgggcg cattattaag cggatggcgg gggaggaagc gcgatgaata
    10141 aaggacttct cacgctactg ctgttattta cctgttttgc gcgcgctcag gttgtagaca
    10201 cctggcaatt cgccaatccg caacaacagc aacaggcgtt aaatattgcc agccagttac
    10261 gttgtccgca gtgccagaat cagaacttac tggaatccaa tgcaccggtg gcggtcagta
    10321 tgcgccatca ggtttacagc atggtggcgg aggggaagaa cgaagtcgaa atcattggct
    10381 ggatgaccga acgctacgga gattttgttc gctataaccc accgttaacg ggtcagacgc
    10441 tggtgttatg ggcgctgcca gtggtgttgt tactgctgat ggcactgatc ctctggcgag
    10501 tgagggcgaa gcggtgaaac agtcacaaat accggtgaaa atgctgacaa cactcacgat
    10561 tttgatggta tttctctgtg tcggcagtta tctgttaagc ccaaaatggc aggcggtacg
    10621 tgcgcaatat cagcgtcagc gcgatccgct acatcagttt gccagccagc aaaccccgga
    10681 agcgcagctt caggtattgc aggataaaat ccgcgctaat ccacaaaaca gcgaacagtg
    10741 ggcgttactg ggcgagtact atctgtggca aaacgattac agtaattcgc tgctggcgta
    10801 tcgtcaggcg ttgcaactac gtggtgagaa cgctgaactg tatgcggcgc tggcgacggt
    10861 gctttattac caggccagcc agcatatgac cgcccagact cgcgcaatga tcgacaaagc
    10921 cctcgcgctg gactctaacg aaatcaccgc tctgatgctg ctggcttccg atgcgtttat
    10981 gcaggcgaat tacgcgcaag ccatcgaact atggcaaaaa gtgatggatc tcaactcacc
    11041 ccggatcaac cggacacagc tggtcgagtc gattaatatg gcgaaattgt tgcagcggag
    11101 atcggattaa tcatctggtg atgaagatta tgttattgag ctgcataaaa aataatcgaa
    11161 tgaacatatg ccaaaaataa tcaccaatca gtattattgc agattaaaca aataaaaatc
    11221 tttccataac aaatggttat tcattaatcc tgccataaac tcgcgttatt atgcattaat
    11281 gcagcgaaaa gctctgttgt taaagggttg cgcaacatac cgcgcaaatg atactgatca
    11341 taagcgttaa aaaaatctac aaaccaacgc aacacaattc atgccctggc agtatgtcac
    11401 gttctcgcgt ttctgaacgg ggaacggcgc tccattgagg aagttattct gatgaaaaat
    11461 ataaaattca gcctggcctg gcagattctg tttgctatgg tgctgggcat tctcctggga
    11521 agctacctgc actaccatag cgacagccgc gactggctgg tcgtcaattt gctctctccg
    11581 gcgggtgata tcttcatcca tctgattaaa atgatagttg tgccgattgt gatctccacg
    11641 ctggtggtgg gtatcgcggg tgttggtgat gccaaacagc tcgggcgtat tggcgcgaaa
    11701 accattatct acttcgaggt gatcaccacc atcgctatca ttttggggat cactctggcg
    11761 aacgtcttcc agcccggtgc cggggtggat atgtcgcagc tggcgaccgt cgatatctcg
    11821 aaatatcaga gcactacgga agcggtacaa agcagttccc acggcattat gggcacgatt
    11881 ttgtcgctgg tgccgacgaa cattgtggcg tcgatggcga aaggcgaaat gctgccgatc
    11941 atcttcttct cggtgctgtt tggtctgggg ctttcctccc tgcccgcgac gcatcgtgaa
    12001 ccgctggtga ccgtgttccg ctccatctct gaaaccatgt ttaaagtgac tcacatggtg
    12061 atgcgttatg caccggtggg tgtgtttgcg ctgattgcgg tgacggtggc taactttggt
    12121 ttctcttctc tgtggccact ggcgaaactg gtgctgctgg tgcatttcgc cattctgttc
    12181 ttcgcgctgg tagtgctggg aattgtggcg cgcctgtgcg ggttaagcgt ctggatcctg
    12241 attcgtattc tgaaagatga gctgattctg gcgtactcca ctgccagctc tgaaagcgta
    12301 ctgccgcgaa ttattgagaa gatggaagcc tacggagcac cggcgtcgat caccagcttc
    12361 gtggtgccga ccggttactc ttttaacctt gatggttcga cgctgtatca aagtattgcc
    12421 gctattttca tcgctcagct gtatggcatt gacctgtcca tctggcagga aatcattctg
    12481 gtgctgacgc tgatggtgac ctcgaaaggg attgctggcg tgccgggcgt gtcgtttgtg
    12541 gtgttgctgg caacgctggg tagcgtaggt attccgctgg aaggcctggc gtttattgct
    12601 ggtgttgacc gtatcctcga catggcgcgt actgcgctga acgtggtggg taatgcgctg
    12661 gcggtgctgg tgattgccaa gtgggaacac aaatttgacc gcaaaaaggc gctggcttat
    12721 gagcgtgaag tgctgggcaa atttgataaa actgcggatc aataattgaa gattgccggg
    12781 gttatccacc cggcaatgtg tggatgcctg atgcgacgct ggtgcgtctt atcaggccta
    12841 ccttaaccgt tggttaattt ttcaaactct tcacacccgg tatcaaaccc ttccatacag
    12901 ctcaggttca accagtgcag cgccttttgt ttgttcttct cgataaaacc ttcctcaccg
    12961 tttaagaaca tcattcccgc ccagtactcg gaataaccgg ttcgggaaat tgcagagctg
    13021 cgtttgaaat accaggttgc cttgtcatcg tcggccttaa tgcccacgcc gttggcgtaa
    13081 atcaaaccaa gcagcatttg ggcatcgacg gcagagtcgt tctccagatc ttccgaggcg
    13141 ttttctaaca gcgaaatcgc ctttggataa tccggtttac ccgcttgagt atttaccaga
    13201 atatgcgcca gcgttacttc accttcttta ctgcccgctt gcgccgcttt ctctgcaaga
    13261 acttttgctt gtggatagtc cagactgacc ggattggtga ttttgatctg cgccagcagc
    13321 gcgcaggcat cagcatcacc gctgtcggcg gctttctgtg cccaatattc ggctttgctc
    13381 aaatcgccgg agctaaacca gctgtcggca agaaaatatt gtgcgcgtcg gtccccggcc
    13441 tctgctgcct ttaaatactg gctgccaggc tcggagtcgt tcgcgtgggc aaagaatgtc
    13501 aaaaacaaca tcaatgcgat aatttttttc attttgataa tacgattggg tagggagtaa
    13561 ccagtataaa gagttcgaat ggataaaaaa acagcctccg aaaggaggct gtagaaagga
    13621 ctgtattacg ccagtgccgc ttcgcgcagg cgagttttca acttgttgta ctcgtcaatc
    13681 acgtactgct cggcggcgcg ctgatcggcg atcggctcga cgcgcacggc gcagtatttg
    13741 tattccggcg ttttcgtaat cgggcttaag ttttcggtaa ccagctcgtt acaggcacca
    13801 atccaccact ggtaggtcat gtaaatcgcc cctttgttcg gacgatcgct gacctgcgca
    13861 cgggtgataa ttttgccttt acgcgagtgc acccaaacca atgcctcatc ttcaataccc
    13921 agacgtttgg cgtcttcggt attgatttgt gcgtagccag gttcatcagc cagcgccgcc
    13981 agtgccgcac agttaccggt catcgaacgg caagagtagt gaccaacttc acgcaccgtt
    14041 gacagtacca tcgggtactc gtcggtgagt ttgtcgattg gcgctaccca gtcgcaggtg
    14101 aagaactgcg ccagaccgtt cggggtatca aacttctctt taaacagata agaagtcccc
    14161 tgatcggcat ctgaagtatc gcggcaaggc cactgaatga agcccagttc gcccattttc
    14221 tcgtaagtcg caccgtagaa atccgggcac agatgacgca actcatccca gatctcctgg
    14281 gtgttgttgt agtgcatcgg ataacccata cgggtggcga tttcactgat gatttgccag
    14341 tccgttttca gatcccattt cggttcaact gctttgaaga aacgctggaa gccacggtca
    14401 gccgcagtaa acacgccttc atgctcgccc cacgacgttg acggtaaaat aacatccgcc
    14461 gccgacgcgg ttttggtcat aaagatgtcc tgaacgataa ccagttccag atcttcaaag
    14521 gctttacgta ctgccgacag ctccgcgtca gtttgcagcg gatcttcgcc cataatgtac
    14581 gcggcacgca cttcgccatg cgctgcgcgg tgcggcagct cgctgatgcg ataaccggta
    14641 tgagcaggca ggctttccac gccccaggct ttggcgaatt tctcgcggtt agccggatct
    14701 ttcacgtact ggtatcccgg atacgtatcc ggcagcgcgc ccatatcgca ggcaccctgc
    14761 acgttgttct gaccacgaac cgggtttaca cccgcatgcg gcttaccgag gttaccggtc
    14821 agcatcgcga ggctggtcag agaacgcacg gtttccacgc cctggtagaa ctgggttaca
    14881 cccatgcccc acaggatggc ggcgcttttc gcctgggcat acatccgtgc cgcctgacga
    14941 atctcactgg cgctgacgcc ggtgatatct tcaaccgact ccggcgtgta gccttcaacg
    15001 attttacgat actcttcaaa gccttctgta cgggaagcga cgaacgcttt gtcgtacaga
    15061 ttttcttcaa taatgacatg gcccatcgca ttcaacagcg cgatgttcga gccgtttttc
    15121 agtgcaatgt gcatgtcagc aatgcgcgcg gtttcaattt tgcgcggatc gcagacgata
    15181 attttcgccc cgttacgttt agcgttaatt acgtgattcg ccacgattgg gtgggaatcc
    15241 gccgggttgt acccgaaaac gaacactaaa tcggtattat caatttcgtt aatagcattg
    15301 ctcattgcgc cattaccgac cgattggtgc agacctgcaa ccgatgggcc gtgtcagaca
    15361 cgagcgcagc agtcaacgtt attggtacca ataacggcgc gcgcaaattt ttgcattaca
    15421 tagttggttt cgttacccgt accacgcgag gagccggtcg tctggatggc atccggaccg
    15481 tacttctctt tgatggcgct caggcgctcg gcaacgtaat tcagtgcctc atcccaggaa
    15541 acaggttcga gtttgccgcc acgctggcga cggatcatgg gggttttcag gcgcggggtc
    15601 aggatctggg tatcgttaat gaaatcccag ccataataac ccttcagaca cagggtaccc
    15661 tggttggttt tcccctgcgc tgcctccgcc cggacgattt tgccgttatc gacgaccagg
    15721 ttgattttgc aacctgatgc gcaatagggg caaaccgtga cgactttttt catcggtctc
    15781 gctccagtta atcaaatcac gcatacgcgc tctcgactac agtatgcatc ttttatgcca
    15841 cattttattt ggggtcattc cctgatatta cgggcactat ttattcaaaa ctctgacgaa
    15901 aaacaggctg tcgtcagttt tgacgtgacg aaacgaaata ccgcgtgaca gccatcacgc
    15961 ggcagacatt ttattttttc tcgacgacgg gagccgcctg atacccgccg cccagcgatt
    16021 tcatcaactg aatgctttgg atcacccggc ggctgtccag catcagtaat gacatctctt
    16081 cggcaagtac tggcaaccgg gcttcagtgg cctgtaagcg gctggttaag ccgcgctgat
    16141 aggcggcctc ggcagcgcgc tgggtgaagc gcgttgcttc cacgcgttca gcctgcattt
    16201 ctcgctcgtc gttgagcgtt tgcagacgcg tgccgttgac ggcaacgtca cgcaccgcgt
    16261 tcagtactga ctggttgtaa cgttcaatca tcatgttgct ggcggcgcgc gtgccttcga
    16321 gattggcatt caaccgtcca ccgtcaaaca gcggcaattt cagacccggg atgaagttga
    16381 actggcgact ggtttttttg aataaggtat ccaggtggat ggcatcaagg ccgaaaaacg
    16441 ctttgatatc aaagctcggg tagaacagcg cccgcgcgga atccacctga tctaatgacg
    16501 cctgaacata ccagcgcatg gcttgcagat ccgggcgtct ggcgagcaac tcataagaga
    16561 gtgtcgccgg aatgccggtc tggactcgtg gtaatgccac cggtttgatc tccggcatat
    16621 cgctggcccc cgcgccaatc aatgcacgca gagattctcg cgtttcggtg atttgccctt
    16681 tgacggcagc aatttgttta tcgaccgcca gaatctgtgc ccgcgcgccg tggaaaggca
    16741 cttgtgcttc cagaccgtgc gccactttac tctggtgcgc tttcaccgcg taatcaatca
    16801 catcgcgagt ttgttctaac agatcgagca tctgatagct ggcctgcata ctgtaataaa
    16861 gctgcgctac gcccgtggtc agcgatagct ctactgctgc ggtttctgcc agcgcggcat
    16921 tatgcgcgcc aatggcggcg gcaaccgctg agcgatgcac accccacaaa tcaagatcca
    16981 gtccggcaaa caaacctact gtggcttccg tatagtacgg cccgtccata cccagtgcgg
    17041 gcgcatccat cgcataaggg cttaaaaagc cgttcgccga gacgcgttgg cggttgagca
    17101 tccctaacgc tgcgacctgt aattgtgaac cggcatctaa caaatcggcc tgggactgcg
    17161 ctttttcttc ccgcagtttc gcttcggcga gggtgtgtga accacttagc gtccgttgga
    17221 tcagcgcatc cagctgcggg tcattgagtt gtttccacca ctgcgcctgc ggccagccgg
    17281 agctggcaag atgaatatcg tcggccagtt tgatttgttc cggtttgagc tgttgatgag
    17341 gtgcagaatc cttacgtacc agggcacagc cggaaatcag cgtcgtgctg ccgagaatgc
    17401 tgcacaacag cagacgtgaa agttgacgat tgatcattgc gtggctcctt gtgcctgttc
    17461 cgtggcgggc gttaatgccg gggctgtcca gtctggcaag cgggcgaaaa gctggcagac
    17521 gtgttgctcc tgttttaata aggtgggcag gatggcctgc gaggcgggtg tctcttcaag
    17581 cgttatttga ggagaacggc tgagtgcggt tgccagaccg gcagcgtatt tctccagggc
    17641 gtcggcaaac tgagctgctc tgtccggctg tagtgcgtta tccagcgcct gcgccgagtt
    17701 ccaggtggca tcccaggcgt gaagaatatc gcggccctga cgaataaccg tttgcgaacg
    17761 ttcaatcagt aaggcgcgtt cttcgctgtc cagttgacgc tccagcgcca cgcgttggca
    17821 catctcttca caggcattaa acgccgcatg cagaccgata cgaatttgca gataagtgcg
    17881 cagagccgtg acttcctgct ggcgtgggat ccgcattact ttacttaaca tacccagcgt
    17941 gccagccagt ttttgcggca gtgtgcgcgc ttcactttca ggccagacaa aggtgtaaat
    18001 caccgcggac accacggtac caatgatgat acccatggcg cgatcgcgaa cttccaccag
    18061 gtcgtacacc gggccaaaaa cgttttcgag cgtggcgagc gcgaaggtga ccaccatctg
    18121 tgtgccgata taagaagagc gttcagagct ggtggcaatc catgcgccca acaggaaaat
    18181 cggtgccagc acaaacagca attcgacaat attgtccagc cagggcatga ccagtagcgt
    18241 gaataacagc gccagaatcg cgccgcaaaa ggccccgcca aaacgcagca ccatcttctg
    18301 gtacgacgaa ccgacatttg ggttagcgac gatcacgcat gtcagcatac aggtgtgaat
    18361 gccttcccag tccacgccgc tgtagaaggt gtaacagatc aaacaggcga gcagtgtttt
    18421 taccgcgtag cgcatatagt ctggattggt aaaagcatcg gcgaccattg atggcggttt
    18481 ggcggcgggc gttggcggcg tattcgggtc catctgaccc agttgtaaca acgtctggca
    18541 gatattctcc aggttacatt cccgtgccgc catcgcttca ctttcagtga tccgccagtc
    18601 gctttgccag cactgacctt cagcaacggc atgctgcagc ttattgattt ctgaggctaa
    18661 tttttgccga aattcaataa ttgcctgaga atcagcaaaa gaggtgggat cgtagcgatt
    18721 cagcgtcgag taaatgtagg ttaccgttgc cacgcagctt tgccaccatg cgctttgagt
    18781 tcgccagttg gcatcgtccg cgagacaaaa gacattcagt ttttgcagcg ccagcgcctc
    18841 tctttcaatc cgcgtttcgg gtagcggtgc gaggctgtcc gtcaggtgac taatggcatc
    18901 atcaagccga tcattaagcg cttgatgcat ttgcgtaatg gcacgactgg gaaaccacag
    18961 cacgccgatt aacgtcatca gcaaggttgg atagaggcca acaacgatac accacagcgt
    19021 taagcgcacg accacttccg gatagtcgag catggcgggg aaggtttgcc cgtaaatggc
    19081 gacaatggcg acagcgaaaa agaccagtcc cagccgatgg gtgcgcatca aaaacataca
    19141 gcccatcagg atcggcccgg cgatgatcaa tcggatcaac ggttcgccgt atgaccattt
    19201 gtagatcaaa aacaggctgc cgatctccag caccgtggca accacaaaca agatcgcgac
    19261 aaatttggtg taaaacgcgt tcgactgaat accgtaaaac agcactgcca gcgataacgc
    19321 cacaaaaggg atctcaaaag tcatcgagat cagaatcacc agcaggcagc ctacccagag
    19381 ttgcacgatc tgcggcacgc ggccgggtcg ccgctcgctt aactcttcat gaaagaacgc
    19441 cagcagcctg accaccggta atggcaggga gttgagcgcg ctcattattg cggctcaaga
    19501 ttagcgactg ccgaagcgcc gatgcggaac atttccgggt caggtttatc gaccatgatt
    19561 ttgaccggaa aacgctgggc aacgcggacc cagttaatag agcgagaaac tttcggcagg
    19621 ccgcccagca ccaggccgcc gtcatccggt agcacgccgt agccaatcga atccacttta
    19681 ccctcgaagg ttttgccgct gtcactcatc aggcgaatcg ttgcgggtgt acctgagcga
    19741 atatttttca gatcggtttc gcggaagttg gcgatcacgt accagtgacg agtgtcgatt
    19801 agggtaaaaa tagggcgcat ggcagaagca aattgcccga cggaggtttt gagggaaatg
    19861 acccggccat caaacggcgc gcgaacggtc gccatttcca gatgaagttt ggtcagggca
    19921 atatccgctt cgaccgccgc acgttgcgcc accagcgcat cgacgccgct gacggcgctg
    19981 gcggctgact gcgcctgtaa caatacggca ttaagatcgg cttctgcggc gcgctgcgca
    20041 gttcttgcac ggtcaacgtc ttccgctgag acaaaaccct ctttcagtaa tggctcggtg
    20101 cggcgtaatg tatctgtggc ctgtttcgcg gcggcacggg ctttttctac cgtggcatta
    20161 atcgagtcgg caccaaactg ttgcgcatca acgctacgct gggtgagcat aatttgctta
    20221 tccagcgccg cgagggaggc ttcagctttc gccagattgg cttcgtacgg gcgcgggtca
    20281 atgcggaaca gcaaatcgcc ctgtttgact gcctggttgt cggtgaccgc cagttctaca
    20341 atgcggccgc tgacttccgg caccacatca atggtatctg ctgacgcgta agcgtcatta
    20401 gttgatggcg cactgtctac gcgccagata acgaaaacaa gggcaaccag cgccaatgca
    20461 accactaaca gagcagggaa tttactgcga ggagcttttt tcggcgtact ttccatgagc
    20521 gcgtctcaaa tagattagaa aaatgccagc cagaacagca tggcgtagag agcaaaaagg
    20581 gcggtataaa taattccgac aaatgccaga ttgatatttg cccgctgaat aactcgcctc
    20641 gtgatgagca tcaaaataag gctggcaatg gcgcagaaaa accagctggg ataataagca
    20701 ccgatcaccg ggattgccgg agataatgag catcccgaaa ccatgaagac gggaattatc
    20761 caggctgttt ttttgagttg catcgccatg cgagagagaa ctgttggcat attaaataca
    20821 tcctgtctgc tgcgaacaat atctgtagtg aatatcaata tccattgaag gcgtcagtat
    20881 ggctattttc tcgatgaata aaaatagctt tattcagcca ccgcattcat aacttatata
    20941 ttttatttat taattggctg tatatatttt taaaataaat gcttttgggg gcttcagcgc
    21001 ccccaaaagc gagtgacatt aatttggggt tacgatattc acccacaaat cgaaattatc
    21061 cagacaggcg ataatttctt ccagtttcgc gccattgcca ataattttgg ctttcttcgc
    21121 ttttaccaga tccgccattt tggcttgccc ggtcagcacg gcgtgcagat cttcacggct
    21181 gatgtagaaa gaggcgtcag cttgggattg cagtgtttta cggtagttaa gcacgctatc
    21241 gttcagcgtc aggttgaggt tatcgccatt gctcatattg aagttcaggc tgatattttt
    21301 acccgcggct ttcgcgctat cgaggcgaac ggacataaag tcgaacagca tttcgaccga
    21361 catcccgcga atggtgtccg gggaaccggt ggtgccgtgg ctgaacttat gcaccccttc
    21421 gcgcagctct ttcgcgccgg tcaggtagaa accgcgccag gtggcggact cggcctgata
    21481 gcccagctgt tcaaagttat tcgcttgcag attcttcgcg acctggtcac ccgggttggc
    21541 ggcaatcacc tgtttcagca gttctgccga ccagcggtaa tcaccttgct tgttcgcttc
    21601 ttgcgccagg ttgatgacac gggcagaacc gcccagcgcc tgcacgtaac gtttacccat
    21661 ctccacctga ccatacggat gcaggttagc cgggttaccg tcgtaatagc caagatagaa
    21721 gttatacacc gcgcgggcgt tgtggctgac agaaccgtaa tagccacggc tggcccagtt
    21781 attggcaagt gcaggcggca gtttaatcat gtcgccgatt tcattcatgg tgtagccctg
    21841 gttcgccagg tgcagggtct ggtcgtgaat gtacttgata gtatcgcgat atttaccaat
    21901 ataatcattg atatgcttat tgccccagac cggccaggtg tgcggcataa acaggacttc
    21961 cgcgtcgtta ccccacatat ccagcgtttc gttcagatac tcggtccact tgctggtgtc
    22021 gcgggttttc gcgccgcgta gagtgtagaa gttgtgcagg gtatgcgtgg cgttctcggc
    22081 ggtacacagc gctttcaggg ccggaatata gaagtgcatt tcggctggtg cttcgctacc
    22141 tggggtcatc aggaagtcaa actccaggcc gtcgataatc atcttctcac cggttttggt
    22201 gatggttttg ttcggtgcga tgatgctcgg gtagcccgat gccagcgtta cgccaagacc
    22261 attgccgatg ttaccctgag ggttatgcgc cagcagcagg ccgtaggagt aaagtgcacg
    22321 gcggctcata atattacccg ccagtacgtt ttcgctgatg gcttcgtcca taaagccagc
    22381 aggggcgata acctgcactt taccggattt cacatcggct tcagagataa tgcctttcac
    22441 gccgccatag tggtcggtat ggctgtgggt ataaataacc gcaacaatcg gtttttgcgg
    22501 gcgattttgg aagtaaaggt caagggcggc ttttgcgctc ggtggcgtca ccagcgggtc
    22561 gatgacaata atcccggtat caccttcgat aaaggtgatg ttggagatat cctgaccgcg
    22621 aacctggtac attctgtcgg tgactttaaa caggccggaa ataccgttta actgcgactg
    22681 acgccacagg ctagggttaa cggtttcggg cgcgggcgca ttgatatcaa atttataatc
    22741 ttccccgcga taatatggtt tgccattagc atcgcgcaga ataccttcat ccagcagcgg
    22801 agcgataaat ccacgctgag cgtcgtcaaa atcctgacga tcgctaaacg gtaatgattt
    22861 ggcgtaattc tgattaacct gttgggtata ttgagtggcg gctttcgctt catctgttgc
    22921 gtaagcggta tttaccatca tgccgctggc ggcagttaac gcaataataa ttttgctcaa
    22981 acggaataac cgagagttat tcatataaat ctccatttat catttatgtc gtaaatatgt
    23041 aatccatgca aaatacgtca tttaaagctg gggttatcat aattgggaat ttgcgacttt
    23101 aataagtgga agtgtgagct gaacgatcca ttttattagg catttgtgct gaagaggaaa
    23161 agttacagta aaactatcat tgcagaaaat aatatgagcc gttttatgtg tttattatat
    23221 atattgtacc tgtcgttggc acagcgggac attgcgctac tgtgccaacg ctttactcat
    23281 ggggctttag cacaggactg tggcaaaaaa tgttgatgcg ccaatattgc tgcaccctga
    23341 gcgccattaa agtcagaaga tgaggcggca ataaagcgca cgacctgatg cggcagtgga
    23401 cggcgcaggt acttttgggt catggcaatg agagtctcgc gtgggaaggc gggcatatcc
    23461 atcacgccac cgcccagaat caccgcatcg ggatcgaaca gattaatgct ggtggcaatg
    23521 gcccgtgccg cgttttcaag cagactctgg acgaaagggg cgttttccgc atggacgaaa
    23581 aggtcgctca atgggtaatt tcggggctgt tgttcgtacc agcgtcttag cgccattcca
    23641 gagcaattgg tttccaggca cccaggattg ccacacgcgc agtgttgggt catatctccc
    23701 agggggatat gacccagttc gcctgccaca ccgtgtgcac ccgtccacgg cgcaccgttc
    23761 atccacactg cgaaccccat ccccgtaccg agataggccg ccagaaccag ttgttgcgta
    23821 aggcggtttt ctactacgtc ccaggagagt tgcaggttaa cgtcgcggga aaactcaacc
    23881 ggacaattca gcgtattttc gagcttatcg gcgagatcat ataaatccgc cgctgttaac
    23941 ggcaggttag gcgtagaaat tatggtgcgt ttatctttac tgaccagcgc cggaaatccc
    24001 atcaccagac catgacagcg agcgttaaag cgcctgagtt gctcgtcaat catttcgccg
    24061 atacccgaca ccaggccggg agcaatgact tctgcggtcc gctttttttc gcagtgtagc
    24121 gtttcacctt ctgctgtccg cagacaaaag cggatatgcg ttgcccccat atccacgccc
    24181 gctacgacgt tatgctgttt ttgcatgagg ctgtacctcg ctttttgcag ccagaatctg
    24241 cgtggtcata attctccatg cttcgtcgat attttccgca tgattaaaca ggccggaagt
    24301 gccgacgata aagacatccg cccctgccgc catcagtttt tcgtaagttg ccttgttgca
    24361 ggaaccgtcc acctcaattt cgtactccag accttctcgt tcacgccatg ccttcagttc
    24421 ggcaagttta tccagcattt caggaatgaa cggttgtccg gcaaagccgg gatcgacagt
    24481 catgaccgta attttatcgg ccttatggat atagtatttc atggcctcaa ctggtgtctc
    24541 cgggttaagg atcagcccca ctttcatgtc atgacagcgg atttcatcaa tcaggcggaa
    24601 cgcctgaccg ttgatagttt ccggatgcaa agtgatgaaa tcagctcccg cacgcgccag
    24661 ttgagcaatg taatcctgcg gccgcgtcac catcagatga cagtcgagcg gtttagttgc
    24721 cagtttttta acctgactta cgaagaacgg tgagagtgtc agattgggga caaagtgacc
    24781 atccatgata tcgatgtgaa agtaatcggc atggctgtcg ataaattcga tctgttcttt
    24841 aaatttcagc agatccatac acattaacga gggggagatt ttcatgttca attccttact
    24901 tactgataag acggtcaagg gcgacagccg cgataattaa tccgcccatc accaccagtt
    24961 ggtaataggt ttgtacctgc aaaatattca gaccgttgtt gatggtgccg atgatcaacc
    25021 cgccaatcac cacagagaaa atgcgcccct tgccgccgaa gaaactggtg ccgccaatga
    25081 tggcgctggc aatggcatag gtttcaaaac ccataccggc aagcggttct gcggcaccga
    25141 gtcgtgcagt tgagacgacg cctgccagac ctgcacaaac accagagatg ataaacacca
    25201 ccaggatgtg gaatttcacg tcaatcccgg aatagaacgc cgaatttttg ttgccgccca
    25261 gtgcgtagat gttgcgcccg agccgcatac gcgttgtcag aaaccaaagg atgagcgcga
    25321 caattagcga gaagataacg gggacaggta tcccaattac gctggcggca aagaagttca
    25381 cgaagtcaaa ggagaagccg tataccgagt tggcatcgga gatcaccagc gtgatcccac
    25441 ggaaaatcgc gttggtgcca agggtgatga tgaacgggtg tagccccgtc cagttgacca
    25501 ggcagccgtt gatcgccccc agtgcgccgc caaccagtac accgccaatc atcgctgcga
    25561 gaaacgggtc aacacctgcc aacatcagtt tggcggtcac cataccggaa agcgccagaa
    25621 tcgcgccaac cgagaggtcg ataccagcga ccaggatagc gaaaaactcg cccatgccga
    25681 tcaataccgt cacggagctt tgaacaaaaa tctgggtaat attattggtg gtcagaaaat
    25741 attctggcga cagcgaacca aaaatggcga cgatgatcgc caggataaaa aaggtgccgt
    25801 atttatccca gaacagcgca aagttgaacg gtttcttctc gctcgcttcg ctttttactc
    25861 ttgtggtaaa gcccatgcca taatctcctc ttcgctcatg tcatcgcgat tcgtcaggat
    25921 ttgcgtcagt cgtccttcgc agaacacggc gatgcggtcg cagacggtga taatttcagg
    25981 tagttcagat gacaccatca ggatgacttt tccgtcgtcc gccagttggc gcatcacttt
    26041 gtaaatttcg gctttcgcgc caacgtcgat gccgcgggta ggttcatcga aaataatcac
    26101 ttccgggcaa cagcacagcc atttggagat caggactttc tgctgatttc ccccggagag
    26161 ttcggtgata ttctggttta ccgaatgaca tttcagcgcc agcagttcgc gttgattttc
    26221 agcggtacgt tgctcgtcaa cttcatgaaa caagcccatc gcgcctttat agccgccgtc
    26281 tttcagactg cggctgatcg ccatgttctg agcgatggaa aagttgggaa aaaaaccgtt
    26341 atcccggcgg ctttcagtga tgtaagccat cccttttttc actgcatcca ggggggaacg
    26401 tggagagata tctttgccat taagacggat ttctccgcca gcgcgtttat caacgccaaa
    26461 cagacaattc atcagttcag tacgtccgga accgaccagc ccggcaaagc ctaatattct
    26521 ccccggcaga cgctaaatga gatatcccgg accttttttc tgtcacggct ggtgacgttg
    26581 cgcacctcaa aaaccgtatc gtgcacaagg ttgctgacat tctccttcat cgcgttaaaa
    26641 cggttttgca gttcgcggcc taccatcaga cggacgatat cgtcatttga cacatcgctt
    26701 accatgccgc tgcaaacgct gctgccgtct ttcatcaccg tatagcggtc gcaaatacgg
    26761 cgaatttccg ccaacttatg cgagatatag acgatggccg taccctcttt acgcaactga
    26821 ttcatgatca gaaacagata gtccacctct ttattggtga gtgaggaggt gggttcatcc
    26881 atgatgatga ctttggcatc gagcatcagc gttttggcaa tttccagcat ctgcttgtgg
    26941 ctgatagata gattcgccac tttctcatct aaatcaactt tcaagcccac gcgtaataac
    27001 atcatggcgg cgcggacacg catttctcgc cagtcgataa tattgacgcc acagattttt
    27061 ttcgtcagat gacgaccaat atataaattt tccagtacgg ttaattcatc aataacgctg
    27121 agttcctgat aaataatccc gataccgagt tgtgccgcta atttatgatc cagcttgtta
    27181 tagctaatgt tattaatggt aatggtgcct ttggtcggct catgtattcc ggataaaacc
    27241 ttcattagcg tggatttacc cgcgccattt tctcctagta atgcatgtat ttcaccagga
    27301 taaaccgtta aattaaccga ctttaatgcg tgaaccggac caaaggactt gccgatcccc
    27361 gccatcgata tatatggcgt ggccataaat aacctctctg cacgaaatat cgtattattg
    27421 cctgatggct acatttatca ggtctacgtt caggttattt tgttggccgg ataagacact
    27481 tcattagcat catcatccgg catcattcag ttttattgag tgaccaggat tgaatcgacc
    27541 agtttaaatt ccggtgcttt atccagcggg ataaccttgc cggatttctc agcgttaacc
    27601 atcagcttca gacccgttgc gccaatatct gccgggttct gcgcaaccgt cgcggtcatt
    27661 tgtccggctt ccaccatttt gcgggcttcc ggaattccat ctgtaccgac gaccaatatt
    27721 ttgcccgttt ttccggcgtt tgcgactgcc tgagcaacac ccattgccat cgtgtcattc
    27781 gcgcaataga tcgctttaat attcggatta cgttgcaaca cgttagtggc gacatccagt
    27841 gctttaatgc ggtcccagtc agcgggctgg ctggcgacaa gcttgatctg gcttgctttt
    27901 ttgaaggctt cggtggcacc attacgacgc gcttcaccgg aggcgttgcc ggctttaccc
    27961 tcaatgattg cgacttcacc accttcagcg cccaatttgt caataatgaa cgacgcgcct
    28021 ttcgccccga cagcaacgtt atcggtggtg acaaaagctt ccacattgcc gccagctttt
    28081 ttcagattat ccatgtcgat tttttcatcg agattaacca gataaatgcc ttttttccat
    28141 gcgcgggcga caggcatgac cagattcact gaggataatg gagcgaaggc gatacctttg
    28201 taatttttat tactgagatc ttcaaataac tgcaattgag attgaaaatc gccttctgaa
    28261 ggagaggcaa aaatatcaac gctgacgccc agtgtttttg cttcatcttc aatgcctttt
    28321 ttcatatcta cccaaaatgg gttggagagg gttttcaata cgacagcata ttcggcggca
    28381 gcaaaagcgc tggttgacaa cattaagccc acgagtgtgc cgctgaaata tttcagatat
    28441 ttattcataa taatgttctc acggtaaggg gacaggtaac tccgcgatgg cggaattacc
    28501 tttttcttat ttcagcgcgc ctggtgagaa gaaatcaaca attgcgccgg ttttttgcat
    28561 attaatatta gcttgttcaa tgttgagctg ggcgacagag acaaaaaaag cgtccagcaa
    28621 agttagttgt aatattcttg ccgaggcatt acgacctaat aacggcgttt ccggggctgg
    28681 tgagcaaata atataatcgg ccagtttcgc tatcggtgaa tggtagctat gggttataca
    28741 aataatcttt gccccgttct tttttgccag ttctacggcc gcttttacat cactggttcg
    28801 cccggaatgg gtcactacca gcacaacatc tccttcctgt aacaacgaag cggacatcat
    28861 catgatgtga gcatcaggat aggcctgaca gcgtacgcca atgcgcaaga acttgtgctg
    28921 tacatcagca cagatagcat ttgatcctcc ggcaccgtac aaatcccgct gtctggcctg
    28981 atagaaaaag cgggcggcac ggtggatctc atcaacgttg acgatcgact gaccttccat
    29041 aatggtgcgt aaagtgatgt taaatacctt attcaccaca tcctgcggcg cttcatcaaa
    29101 agccaactcg gaaggcaata cctgttctga ctgagaaaaa taatcttcca gcgcactgcg
    29161 taagttacga aagccgctaa accccagcag ctttgatacc ttaactatca tcgcttcaga
    29221 taccgacaga gcttctgcga catctttaat tgcgggtgca caactcaggt taccgggttt
    29281 gagtaaccac tctacgatgc ggctttcatt ttctgtcatt ccttcctgct tcattcgcag
    29341 gtaaggcgct aaccctatac cgttcggaag cgctgaatca aactctgact ggctcatcac
    29401 gttctcttgt ccttgaattg aagacgccac tatatcacca cagcaagaac agaaaagatg
    29461 ctggcgactt cacaaaaaaa taaaatttat aaagtttatt ttattgtgaa caatggcgag
    29521 tggcttaaaa ttttatttca tttaattagt ttaaaaacat gatgttattt gtttttctgg
    29581 ttttttagat gatagatgtt gctggatggt gagtgtcttt aacgctattg cgctgtcaga
    29641 tgtaactctg taaaacagat caggaaggcg taattcatcg attttgggtg tttttaattc
    29701 attaacatca caaatgtttt ttgattgtga agttttgcac ggacggggaa gatgaatgaa
    29761 aaagattgca tttggctgtg atcatgtcgg tttcatttta aaacatgaaa tagtggcaca
    29821 tttagttgag cgtggcgttg aagtgattga taaaggaacc tggtcgtcag agcgtactga
    29881 ttatccacat tacgccagtc aagtcgcact ggctgttgct ggcggagagg ttgatggcgg
    29941 gattttgatt tgtggtactg gcgtcggtat ttcgatagcg gcgaacaagt ttgccggaat
    30001 tcgcgcggtc gtctgtagcg aaccttattc cgcgcaactt tcgcggcagc ataacgacac
    30061 caacgtgctg gcttttggtt cacgagtggt tggcctcgaa ctggcaaaaa tgattgtgga
    30121 tgcgtggctg ggcgcacagt acgaaggcgg tcgtcatcaa caacgcgtgg aggcgattac
    30181 ggcaatagag cagtggagaa attgagattc atccactact tgcatggatg agtaatgact
    30241 aatgtggata gagtttcttt ttgaggttgg ctaatgaaac gctttccgct atttctttta
    30301 ttcaccctgc tcacgctgtc caccgttccg gcccaggccg atattatcga cgacaccatt
    30361 ggcaatattc agcaggcgat taacgacgct tataaccctg accgtgggcg agactatgaa
    30421 gattcgcgcg acgacggctg gcagcgtgaa gtgagcgacg atcggcgcag acaatatgac
    30481 gaccgccgcc gccagtttga agatcgccgc aggcagctgg acgatcgcca gcgccagctt
    30541 gatcaggagc gtcggcagct agaagatgaa gagcggagaa tggaagatga gtatgggcga
    30601 tgaggttggg tatggagcag gcatcgcccc tcaccccaat ggggagaggg agaaaaccag
    30661 cgcaatattc aatatcgagc acaatcggtc ccctcgcccc tctggggaga gggttagggt
    30721 gagggggcca gcgcgcacat tccctctcat cacgccaccc caatctccat cccatcaaac
    30781 cccgcctcaa aacccggcgg cagcgcattc tccatcagcc acgcatcaaa ctggtggctg
    30841 atatgggtca gaatcacccg tggcgagtgg ataacctgat tgagcgcaag cacggtattt
    30901 aaatcacagt gattacgcgg cgcatcctcg cgcggcgggt ggctgcaatc aatcaccatc
    30961 acctgcggat gattattgag taaaaatttc tgtgtttttt ccggcaggcc agcggtgtca
    31021 gatagccacg ccacccggct atgtgccgtt tccagcagat aaccgaaggt cagttttgag
    31081 tggttaagcg gcagcggcgt gacctgcaac ccctgcaaat caaataccac aaacggttcc
    31141 actgtgtggc tgaaatcaag caggcccgga tgtttaaaca gatcgtcgca accctggtca
    31201 tccggcgggc cgtaaaccgg gatcggatcg ccaacgcccc agcgcagcgg aaacagcccc
    31261 tggacgtgat ccatatgata atgcgtcagc aaaaactgct ggaacgatcc gggcgaccag
    31321 cgatcggcga gatcgtgcag cccggcgtcg atcagggtga ttgcgtcgtt aaacttcact
    31381 acgccgctgc atggctggcg gcgatactgc ggtgagcgcc gcgctcggtc gcaggccgcg
    31441 cactcgcagc cccatgccgg aacgccctgt gcgccgccgg tgccggtgag cgtgagggtc
    31501 agactcatgt tacagcgcct tggtgaagcg gaagtgactc tgctcgtagc cttctcgcag
    31561 atagaaacgg tgcgcgtcgt ggcgcttcac gttggtcgaa agttcggtca tttcggcccc
    31621 ggcctggcgg gcttcttctt ctgcccacgc cagtaactta ctgccgacgt tcagaccgcg
    31681 cgcctgcggc attaccacca actcctgaat ttcgccgatc cagttgacat gatgcagatg
    31741 aaactgcaaa tgcaggccga tcataccgac aacttcgcca tccagcagcg ccagatggta
    31801 gcgcatgttc gggtcgcgca ggttggcgtt aaagcccacg cgaaacgcgt ggtggtcaaa
    31861 ctccgcctgt tttagctcgc aaatcaacgc gtaaaccgcg tcggtgtcgt actgcgtggc
    31921 cgggcgaagc tcacaagcag gcatggtgtt tctccttctg atggattagc gtcagcagcg
    31981 tgtcgaccga ctggcgcagg ctgccgtcat tattgagcgt atggcaatcc tgtggagtat
    32041 agcgggcggc gcgcgccagc cgggcgttaa tttcactggc gttttcgcgg ccacggtttt
    32101 ccaggcgctg gcgcaggatc tctggcgaaa cctgtaagca aatgggcagc agcgccgatt
    32161 gatagcgcgc ccgcgcctgc ggcagatggg cgcgtgagcc gttgaccagc acgtcgaatc
    32221 cagcgtgcag ccagaggtca atctcgacgc cgacgccata atacagaccg ttagcgtgcc
    32281 agcttaaggc cagcagattt tgccccgcgc gggtaaaaaa ctcctgctcg ctcagggcga
    32341 tatggttttc gcttccagcg ctggcgtcgc gcgtgatgta gcgatgcgcc accagtagct
    32401 gagtttgttc ccgcaggcgg agttccgcca gcaggctatc tttcccggag ccggacggcc
    32461 ccattaacca aatcagtttt cccatcatca gaacaccctt ttaccctgac gccagacgtg
    32521 gtcgatatga atgtggttgc ccttgcgatg cgccagcacc aggtcggcgc gtttaccctc
    32581 gccaatcacc ccgcgatcct ggagattaag cgcttgcgcc ggatttttgg tcaccagctt
    32641 caccgcctgc ggcagcgtaa agcggttgct ctcgtcatcg gcgacgcgga acgccgcatc
    32701 cagcaggctg gcggggtagt agtcggaaga gaggatatcc agcaggccaa gctgcgccag
    32761 ttcactggcc gccacgttgc cggagtgcga accgccacgc acgatatttg gcgcgcccat
    32821 cagcacgttc atgccatgct tgcgcgaggc ttccgctgct tcgaacgtag tgggaaattc
    32881 ggcgatcacg ctgccaagct ggtgggattc ggcaacgtgg gcgtgcgtgg cgtcatcgtg
    32941 gctggcgagg gcaatttgtc ttacgcggca cagggcggcg atagtttcgc gattcggctg
    33001 cgaccagcgt gcggcgagcg ccagttgctc ttcttcgtac tgctgcatct gcgcatcggt
    33061 gagcgagtat ttgccctgat aatactcgcg atacttctcg cggttggcga actggcgctg
    33121 gcccggcgag tgatccatca gcgacaccag cgtcaccggc tcgcgctgca ccagtttttc
    33181 aaacagcggc agcgtagtgt gatgcggcag ttcgcagcgc agatgcaggc ggtgctcggc
    33241 gcggttgacg ccgcgtttct gcgtctcttc gatggcgttg atcatcttct ccagattttc
    33301 cagccgatcg ccgccgtcgc gcacgtcgcc aattgctacg gcatccagta cggtggtgat
    33361 gccgctcgcc accatcagcg cgtcgtggct gctcatcgcc gaatgggcgg gccagtcgac
    33421 tttcgggcgc ggggtgaaga atttatcgag gttgtcggta tgcagctcaa tcaggccggg
    33481 tagtagccag ccaccttcgc cgtccatcgc ttctggcagg cggctctggc tttcggcaaa
    33541 ggcgcggatt tcgccatcct gcacctccag cgaaccgtgc accacctcgt tttccagcac
    33601 cagcttaacg ttattgataa tcatgaagag gctcccattg ggtgcaggcg gtcggcgacg
    33661 tcattacgta cagcttcgtc atggaagatg cctacgatgg ctgcgccacg ggttttggct
    33721 tcgcgaatca gttccaccac cgcggcgctg tttttggcgt ccagcgaggc ggtaggttcg
    33781 tcaagcagca gaatggggta gtcgacgata aagccgcggg cgatgttgac gcgctgctgt
    33841 tcgccaccgg aaaatgtcga tggtgccagg tgccacaggc gttccggcac gttcaggcgg
    33901 gtgagaagac gcgcggcttt agcggcgcag gcttcacgcg gaacgccggt atcgagcagc
    33961 ggctgcatca ccacttccag tgctgagata cgcgggatga cgcgcagaaa ctggctcacc
    34021 cagccgacgg tggttttgcg gatttccacc actttgcgcg ctggcgcggt gaccaggtct
    34081 acccactcgt caccgtgttt gatctggatt tgaccttcgt cgggtagata gttggcgtac
    34141 agcgagcgta gcagagttga tttgccgctg ccggaatggc cgtggagcac cacgcattcg
    34201 cccgcgttga cggtgagcga ggcgcgattg aggacgggca ggcgcacgcc gttttgctgg
    34261 tgcaggatga aggttttact gacgttttgt acgttaatca tttttcgcct cgtggttcgg
    34321 gtgtcggatg cgacgctgac gcgtcttatc cgacctacgg ggagcgcatt tgtaggccgg
    34381 ataaggcgtt tacgccgcat ccggcaccgg ctcaattctg caaaaccgat gacaccagca
    34441 gctgtgtata cggatgatgc gggtcgtcga gcacgcggtc ggttaaccca ctctccacca
    34501 cttgcccctg cttcatcacc agcaaacggt ccgccagcag gcgggcgacg cctaaatcat
    34561 gggtgacaat caccaccgcg aggttcagct ccaccaccag gccgcgcagc aggtcgagca
    34621 ggcgggcctg caccgacaca tccagcccgc cggtcggttc atccataaac accagcttcg
    34681 gatgcgtcac caggttgcgg gcaatctgca aacgctgctg cataccgccg gaaaaggtgg
    34741 tcggcaggtc gtcgatccgg ttggcgggaa tctccacctc ttccagccac ttctgcgcgg
    34801 tggcgcgaat gtcgccgtaa tgacgcgccc cggtcgccat caaccgctcg ccgatattgc
    34861 cgcctgccga gacctgacgg cgcaggccgt cgagtggatg ctgatgcact acgccccatt
    34921 cggtgcgcag caggcgacgg cggtcggcct cgctcattgc atacagcgaa cggttctcgt
    34981 agtgaatctc cccctgctgc ggcgtcagac gcgcggagat cgacttcagc agcgtggtct
    35041 tcccggagcc ggattctccg acaatgccca gcacttctcc cggccataaa tcaaaagaga
    35101 catcgctaaa gcctttgccc ggcgcgtaaa ggtgggtcag gttattgacc gaaagtaacg
    35161 gtttattcat tggcttttcg cctcgctctg ttggcggcaa taatcggtat cggagcagac
    35221 aaacatgcgg tttccggcgt catccagcac cacttcatca agatagctgt gggtcgatcc
    35281 gcagatggcg catggctcat cccactgctg aacggtgaac gggtgatcgt cgaaatcgag
    35341 actttccacg cgggtaaacg gcggcaccgc atagatgcgc ttctcgcgcc ctgctccgaa
    35401 cagctgcagg gcgggcatca tgtccatttt cgggttatcg aatttcggga tcggcgacgg
    35461 gtccatcacg tagcgcccgt tcaccttcac cggataagca taggtggtgg cgatatgacc
    35521 gaagcgggcg atatcttcat acagtttcac ctgcatcacg ccgtactcct ccagcgcgtg
    35581 catagtgcgg gtctccgttt cgcgcggctc gataaagcgc agcggttccg ggattggcac
    35641 ctggaagata atgatctgat cttcggtcag cggcgtttcg gggatgcggt gacgcgtctg
    35701 gataagcgtc gcatcgtccg tacgttcagt ggtgtttacc ccggtcacgc gcttaaagaa
    35761 gttgcgaatc gacacggcgt tggtggtgtc atccgcaccc tggtcaatca ccttcaacac
    35821 gtcgctttcg ccaatcacgc tggcggtgag ctgaatgccg ccggttcccc agccgtaggg
    35881 catcggcatc tcgcgcccgc caaacggcac ctgataaccg gggatagcca ccgcttttaa
    35941 gatggcgcgg cggatcatgc gtttggtctg ctcgtcgagg taggcaaagt tgtagccgct
    36001 cagattagcc atggttctgc tcctgttgca gacgtttgag tagctccagt tcggcctgga
    36061 aatcgacgta gtgcgggagt ttgaggtgcg agacaaagcc tgcggcttcg acgttgtcgg
    36121 catgcgccag cacgaactct tcatcctgcg ccgggcctgt cgcgtgctcg ccgtattccg
    36181 gggcttgcaa cgcacggtca accagcgcca ttgccatcgc tttgcgctcg ctcatgccga
    36241 ataccagccc gtagccgcgc gtgaagtgcg gcggctcatc cggcgggtcg ataaaaccgt
    36301 tgaccatttc acattcggtc atcagcagtt cgccgacgtt caccgcaaat cccagctctt
    36361 ccggcacaat cgacacgtcg atgtaaccac tgcggatctc gcccgcgaac gggtgattgc
    36421 gcccgtaacc gcgttgggtg gagtaggcca gcgccagcaa atagccttcg tcgccgcgca
    36481 tcaactgctg caaacgggaa gaacgtgagc aggggtaaac cggcggcgtg cgggtgatat
    36541 catccggctg tgcgccgcta tcctcttcaa acttcgccag cccctgacgc gccagcaggc
    36601 tgaaaacgtg cggcgacggc tgttgttcgc tgtcggcggt ggtcagcgtc ggcgcttcac
    36661 cgtttgccag cagggtgaaa tcgagcaggc gatgggtgta gtcgtaggtt gggccaagca
    36721 gctggccgcc gggaatgtct ttataaaccg ccgaaatacg ccgttcgaga cgcatctctg
    36781 tggtgtcgag cggctcgctt accgcgagct tcgccagcgt ggtgcggtag gcgcgcagca
    36841 ggaaaattgc ttcgacgtta tcgccgctgg cctgtttcag cgccagcgcc gccagttcgc
    36901 ggtcggcaat gccgccttcg gtcatcacgc gatccaccgc aagattaagc tgctgttcaa
    36961 tctgggcgac gctcagttca ggcaaatcgg tatcgccccg gcgtcggctc tcttgcaggg
    37021 cgtgagcggc gtcgatcgcc ttctcgcccc ctttcacggc aacgtacatc agcacacctc
    37081 cacatgagtg gttcgcggaa tagccagcag gcgctcgccg caggtcagga tcaggtcgat
    37141 gccgagcggg aacgggtgcg ggcgctcggt gagttcgtgc agaatgcact ccggcagctg
    37201 cggagcgatc attcgttctt cggcaatgcc cgcgccggtg agacgtaaca tgcgcccgcc
    37261 gctcaggctg gcgacctgta aaatcagcgt tgcacccgct tccggcgcaa cggcggtgcc
    37321 ggtggaaagg gcgttaagct gttcgctgga aatcgcctca tccgtcaccg cgaaggtcgc
    37381 ctgttccggc tggctgacca gcggcgcgtt ggtatgaaaa cgcaggctct ggctgacgat
    37441 atcgttactc aatggcgcgg caagccacac cggcgtgtcg ttatcggcca gcgtcagcag
    37501 cacgctggtg gtggcgatat tcagcggctg ccagccgcgc ttgagctgat gcagggcgac
    37561 aatcacgccc ggctcgctca tggcctttaa caggcgacga aaactgtgct gggcatcctg
    37621 cacgggaagc ataaaagcgg tttccagggt catgcgttgt ctccgcgaac catcgtaaag
    37681 aagtcgaccc ggctggcgtt cacttcggcc tggcgtgcgg caatgcgtgc catacggtca
    37741 gcgtccagcg gggcaataag ggtttctgat aagttttgaa aatagcgaga ttgctgcatc
    37801 agcgcgtcaa tcagcgcgca gcgttcggcg tgctgtttgt cgcgccccag cacccagctg
    37861 tagccgagcg tgccgtcagt caggcgtacg gcggcgcggg tgagcgtggc gtcgccggca
    37921 aaaaagcgtt cgccggtgcc gcccatccgc gcctgaatct gcaccaggcc ggtttcggcg
    37981 gcgcggataa cctcatagtc ggcggtgatg ttcagtgctt tcaggcgggc tgccagttca
    38041 gccggttggc tgtgcgccag tacggacatc cagtgctggc gggtcgcggt atctgcgtgc
    38101 attcagtgct ccatagtgaa ttcaatcatg tcggcgcgcg tcaggctgac ggagtactcc
    38161 gccgggctgc tttcaccgtc acggtggtta agggtgcgca cgcacagcag cggcgacata
    38221 ttcggaattt caagacgctg gcactctttg gcctgggcgc gacgggcgct gatccgcgtc
    38281 tggctgcggc gcagcgcaat tccggtttgc tcgcgcagaa aatcgtgcag cgaaccgctg
    38341 tcgaagcgtt gcagcgtcgg ccaaagggtg aggtccgcaa agtagtggtc gattaaacag
    38401 agcgcgacgc cgttgacgcg acgcagggtg cgcaaatgga taacgttctc gccctcggta
    38461 atccccagcg cgtcagcgac gtgaccggac gcggggcgca ataccgacag cagtttttcg
    38521 ctggtgggat ggctaccctg gtccagcagg ttctggctaa aacgcgcctg ggcgttgagc
    38581 gggtaatcga acgggcgcat cagcaccagc acgccgacgc cctgacggcg ctgtacccag
    38641 cctttttcca ccagttggtc gatggcgcgg cgcagggtgt ggcggttcac ctcaaagcgc
    38701 gccgccagtt gctgctcggc gggaagatag tcgccgcagc ggtagtgttg acgaagctcc
    38761 tgctcaagtt ttgcggctat ctcctgatag cgtgttgggt agctggtcgg atgtgtagac
    38821 aagtgcatag atatcaatgc ctcgcttatc agataaagtg cttacgcaac cgttgagaga
    38881 ggaaatccag caggctgacc gtgacgatga taagcaccat cagggcgcag gtttgttgga
    38941 actggaaacc gcgaatcgct tcccacaggg tgacgccgat cccgcctgca ccgaccatgc
    39001 cgacgacggt cgccgagcgg acgttggatt cgaagcgata gagggagtag gagatcagca
    39061 gcggcatcac ctgcggcagc acgccgtaga ggatctcttc gagcttgttg gcgccggtgg
    39121 cgcgaatgcc ttccaccggg ccgggttcaa tcgcttccac cgcttcggaa agcagtttgg
    39181 agagcacgcc ggtggtgtgg ataaacagcg ccagcacgcc agcgaacggg ccgaggccga
    39241 cggcgaccac gaacagcatg gcgaagacca tttcgttaat ggcgcggcag gcgtccatca
    39301 ggcggcgaac gggctggtaa acccaccacg gcaccaggtt ttcggcgctc atcaggccga
    39361 aggggatgga gagaaccacc gccagcgccg tgccccagac ggcgatttgc agcgtgacgg
    39421 ccatttcggt gaggtaatcc tgccactggc tgaaatcggg cgggaagaag tcggcggcga
    39481 acgtcgccat gttgccgccg tctttaatca gcgtgagcgg ggccatttcc gcgccctgcc
    39541 acgagacgac caacacggcg agaacaacgg cccagctcag aagcgagaac cagctgcgct
    39601 tgggtggggc gatggtgatg gtttgcatgt ttggctccgg tctgtaggcc ggataaggtg
    39661 cttgcaccgc atccggcatc aacgcctgca cattgtcgga tgcgacgccg gggcgtctta
    39721 tccgacctac gatttactgc accgctttac tcaccgaact catcgcgctt aacgcgttgt
    39781 tcaggcggtc caggtcatcc agctgcgcct gaatctcggt ggtttttgcc agcttgtcct
    39841 gctcattcag tcctttattg cttttcacgc cctgcatctc tttaaacagc gcgagctggc
    39901 gaatcggcac cagttgcagg tcgctggaag cgcggaacgg cgcccagccc aggcgttcca
    39961 gcaccgcttt ttcttccggc gttttgccgt agttcataaa gaagtcgtag atcttgtctt
    40021 tggtggtttc ggaaaggttt ttacgccaga cgatcggatc gcctgggatc agcggcgact
    40081 tccagatcac cttcagttct ttcagcttct ctggcgcgga ggttttcagc ttgtcgaggt
    40141 tttcggtgtt gttggtggca acatccacct gcttgttggc gacggccagc gcgttggttt
    40201 catgcccagc gttgacggtg cgcttaaagt cgctggcgga gatattgttt ttggcaaaga
    40261 cgtagtaacc ggggacgagg aagccagagg tggagttagg atcgccattg ccgaaggtga
    40321 gatctttccg cttcgccagc agatcgttca ggttgttgat cggactatct ttgttgacga
    40381 tcaacacgct ccagtaacct ggcgatccat ccgccgcgac cgtctgggcg aagacctggc
    40441 cgttggcgcg atccaccgct tccattgccg acaggttgcc gtaccaggcg atatccactt
    40501 tattgaagcg cattccctgg ataatgcctg cgtagtctgg ggcaaagaag gcgttcacct
    40561 tcacgcccag cttcttctcc atatcctgta agaatggcgt ccattgcggt ttcaggtttt
    40621 gctgtgattc cgttgaaata atgccgaaat tcagcgcctt ttcctgctct tcggcgtgtg
    40681 ccgggcttaa cagggtgctg aggctgaaca tgctggtgaa ggccagcgag gcaattatct
    40741 tagcgttcat tcgttttcct caatgatggg gatgtcaggc agctttcgcg ttctcttcga
    40801 tgcgattaat gctgcggtag agatggtcaa aacgttcgtt atcaaactgt tggctgctgc
    40861 cgtcgtagaa aacgtgcccc tggcgcaggg cgacgatgcg ttcgcagtag cgcagggcgt
    40921 aatccacctg atgcagcgtg acgaccacgg tgatgccgtc gttctgattg atgtcgcgca
    40981 gggtgtccat cacgatgcgg gcggattccg ggtccagcga ggcgatgggt tcatcggcca
    41041 gaatcacctt cgcctgctgc atcagcgcgc gggcaatcgc cacacgctgc tgctgtccgc
    41101 cggagagggt ggaaacgcgc tgatgggcaa aatgcaccat gccaacgcgg gtcagcgcct
    41161 gtaacgcgcg ctgtttctgc tcgccggtga accagctaaa acaggtgcgc cagaacggcg
    41221 tgctgccgag cgcgccaatc agcacgttct ccagtacgct caggcggttc accaggttga
    41281 attgttggaa gatgtagccg gtgttggcgc ggcttttgcg gatatcgcgc gccagacggc
    41341 cttcgcgctg gactgtgcgg cccagcagct cgatatggct gccggcggat ttatcgccgg
    41401 taatcaaacc gcttaagtga cgtaaaaggg tggatttgcc ggaacccgac ggcccaagca
    41461 gagccaccat ttcaccgtga tgaatgttca gatcaaccgc atgcagcgcc tgatgctgat
    41521 tgaaggtttt ggcgagcttc tcgacacgga taatcgtttg catgatgcag cctccctaaa
    41581 aaagtggctc catcgtggcg gattattgtg acgatttggt taattaaaag tgactaacag
    41641 atgaagagtt aacgggaatt cgatgacagt gcgggagggc gggcctcccg gcgggttatt
    41701 gcgttggttg ttgtttgacg acattaatca tccacggtac gccaaattta tcggtgactt
    41761 tgccaaagcc atgcgcccag aaagtttcct gccaggccat ttcgattttt ccgttagcgg
    41821 caagattgtc aaaccagcgt tttccttctt cgacctgttg cgaatcgagc accagcgtaa
    41881 agccggagta gctggctttt cctgacggta tagcatcgct catcatgatg tcgcttccgg
    41941 caatgcgcac gttggcgtgg gcgatggcgg tatcgggaaa ttgcattccg gaagggcagt
    42001 tctcggcgct gtcctgcgct gattttggca tttcgccgaa gctgatttta tagagcagtt
    42061 cagcgcccaa cgtacgttga taataagcaa ttgcgtcggc acagttaccg gcaaaagaga
    42121 ggtagggact taacggcatg atggtgacct cagttaagag aagccagtta agtgtagttc
    42181 gaaatttata cagatgagag agaagcctga taagacgcgg tcagcgtcgc atcaggcagt
    42241 cggcatcgtt gccggatgcg gcgcgagcgc cttatccggc ttaccgatca caatacaatc
    42301 agttcttttt cacaaactca gatttcagtt tcatcggacc aaaaccgtcg attttgcaat
    42361 cgatgttatg gtcgccttca accaggcgga tgtttttcac tttggtgcca attttcagca
    42421 tcgaagagct acctttcacc ttcagatctt taatgatggt aacgctgtcg ccgtcagcca
    42481 gcagattgcc gttagcatct ttaacgatca gctcgtcgct ttcctgtgca ggttctgcgt
    42541 cgttccattc gtaggcacat tccgggcaga tgtacatgcc gttatcttcg taagtgtatt
    42601 cggagttgca ttttgggcag tgtggtaatg acatgtggat ttcctcaaaa gtcagcaggg
    42661 caaaagcgcc aaaaaacggc agattgccga aaaaggccgc aattatacac aaaatccctg
    42721 agtttgtcgg gggtactgct gattttagac gacgatcgtt ttcatttgaa aggaaacgca
    42781 aaaagaaaat aatctttttg cctctattta ttatttaaga taatgttaat gctctacttg
    42841 ttcttttttt attcacatga tatttttatc tttctgacgt tttaaacgta tcagaagacg
    42901 ttatttattc tgataaaaaa caacacacta aatataaaat tatttcttgc agtaattata
    42961 aaagccgaaa acagaactca aaaacaatct ggctaaataa aagtaacaaa atttgcttta
    43021 aggaagaatt ttctatgtac acacagaccc tgtatgagtt aagtcaggag gctgaacgcc
    43081 tgttacagct ttctcgccaa cagttgcagt tactggaaaa aatgcctctc tctgtacccg
    43141 gagacgacgc gccacaactg gctttaccct ggagtcagcc taatatcgcc gaacgtcacg
    43201 cgatgctgaa taatgagttg cgtaaaattt cccgactgga aatggtgctg gcaattgtcg
    43261 gtaccatgaa agcagggaaa tcaaccacca ttaatgccat tgttggtacg gaggttctgc
    43321 ctaatcgtaa tcgcccaatg actgcgctgc cgacgcttat tcgccatacg cccgggcaaa
    43381 aggaaccggt actgcatttt tcacatgtcg cgccaatcga ttgtttaatt caacaattac
    43441 aacagcgcct gcgtgattgc gatattaagc atctgaccga tgtgctggaa atagataaag
    43501 atatgcgtgc gcttatgcag cggatcgaaa atggcgtcgc tttcgaaaaa tattatctgg
    43561 gtgcccagcc tatttttcat tgtctgaaaa gtttgaatga tttagtgcga ctggcgaagg
    43621 cgctggacgt cgattttcct ttttctgctt acgccgccat tgagcatatt cccgtgattg
    43681 aagtggagtt tgtccatctg gcggggctgg agagttatcc cggtcagttg acgttactgg
    43741 atacccccgg gccaaatgaa gccgggcaac cgcatctgca aaaaatgctt aaccagcagc
    43801 tggcacgcgc ctcggcggta ctggcggtgc tggattatac gcaactgaaa tcgatctccg
    43861 atgaagaggt ccgtgaggcg attttggcgg tggggcaatc ggtgccgctg tatgtgctgg
    43921 tcaataagtt cgatcaacag gatcgtaaca gtgacgacgc cgaccaggtg cgggcactga
    43981 tttccgggac gctgatgaaa ggctgtatta cgccacagca gatatttccg gtgtcgtcga
    44041 tgtggggcta cctggcgaat cgggcgcgcc atgagttagc caacaacggt aagttaccag
    44101 cgccagagca acaacgctgg gtggaagatt ttgcccatgc cgcgctcggc aggcgctggc
    44161 gtcatgccga tctggcggac ctcgaacata ttcgtcatgc tgccgatcag ttgtgggaag
    44221 attcgctgtt cgcccagcca attcaggcgt tgcttcatgc cgcttacgct aacgcctcgt
    44281 tgtatgcttt gcgatctgct gcgcataaac tgttgaatta cgcgcagcag gcgcgggaat
    44341 acctggattt tcgtgcgcac gggttaaacg tcgcttgtga acaattgcgg caaaatatcc
    44401 atcaggtcga agaaagtttg cagctattgc aactcaatca ggcgcaggtg agcggcgaga
    44461 ttaaacatga aatcgagctg gccctgacct ccgccaacca ctttctgcgt caacaacaag
    44521 atgcgctgaa tgcgcagtta gccgccttgt ttcaggatga ttcggagccg ttaagcgaga
    44581 tgcgtacccg ctgtgagaca ctgttacaga cggcgcagaa caccatcagt cgcgacttta
    44641 cgctgcgttt tgccgagctg gaatccaccc tttgccgggt gttaaccgat gttattcgcc
    44701 ccattgagca acaagtcaaa atggaattga gcgagtcagg gtttcgtcct gggtttcatt
    44761 ttcctgtttt tcacggcgta gttccccact tcaacactcg ccagctgttc agtgcagtca
    44821 tttcgcgcca ggatgcaacg gacgagcaga gcacgcgttt aggcgttgtg cgtgagactt
    44881 tttcgcgctg gttgaatcag cccgactggg gacggggaaa tgagaaatcc ccgacagaaa
    44941 cggttgatta cagtgtgttg caacgagcat taagcgcaga agtcgatctt tattgccaac
    45001 aaatggctaa agttctggca gagcaggtcg atgaatctgt tacggcaggc atgaatactt
    45061 ttttcgctga gttcgcttca tgtttgacgg aattacagac gcgtttacgc gaaagcctgg
    45121 ctctgcgtca acaaaatgaa tcggtggtca ggctgatgca gcagcaattg cagcagactg
    45181 tgatgactca cggctggatt tacaccgacg cccagctgtt acgcgatgat attcaaacac
    45241 ttttcacggc agaacgatat tgaccaagac gttactggac ggccccggtc gcgtgctgga
    45301 gtcggtttat ccccgctttt tagtggatct ggcgcagggc gatgatgccc gccttccaca
    45361 agcccatcag cagcagtttc gtgaacgact gatgcaggaa cttctttcgc gtgtgcagct
    45421 tcagacatgg acgaacggcg gcatgttaaa tgcgccgctt agcctgcgac tgacaatggt
    45481 ggaaaaactg gcgtcgatgc tggatcccgg tcatctggcg ctgacgcaga tcgcgcagca
    45541 tctggcgctg ctgcaaaaaa tggatcaccg caagcactct gctttcccgg agctccccca
    45601 gcaaattgcc gccttgtatg agtggttttc agcccgttgt cgctggaagg aaaaggcatt
    45661 aacgcaacga ggcctactgg tgcaggcggg tgaacagagc gagcaaattt ttacccgctg
    45721 gcgtgctggg gcgtataacg cctggtcgtt gcctgggcgc tgttttatcg ttctcgaaga
    45781 gttgcgttgg ggggtatttg gcgatgcctg tcgtctggga agcccgcaag cggtggcgtt
    45841 gttgctgggt gatttgcgcg tgaaagcgac acaacatctg gcagagagta tcaatgcggc
    45901 cccgaccacg cgtcactatt accatcagtg gtttgcctct tcgaccgttc cgacgggcgg
    45961 ggatcatgct gattttttaa gttggctggg aaagtggacc acggcagata aacaacccgt
    46021 ttgctggtca gtgacccaac gctggcaaac tgtcgcgctg gggatgccac gactctgttc
    46081 agcgcagcgt ctggcggggg caatggtcga ggaaatcttc tctgtaaatt tggcgtaaat
    46141 aatcagttac atcaatgagt cctaaacgaa atccatgtgt gaagttgatc acaaatttaa
    46201 acactggtag ggtaaaaagg tcattaactg cccaattcag gcgtcaactg gtttgattgt
    46261 acattcctta accggagggt gtaagcaaac ccgctacgct tgttacagag attgcatcct
    46321 gcaattcccg ctcccctttt gcggccgtcg cgctgatttt tctggcgttt gcggaaatgg
    46381 gccaactctg cgaggaaagc tatgctgaaa aggaaaaaag taaaaccgat tacccttcgt
    46441 gatgtcacca ttattgatga cggtaaactg cgtaaagcca ttaccgcagc atcactgggt
    46501 aatgcaatgg aatggtttga ttttggtgtt tatggttttg ttgcttacgc attaggtaaa
    46561 gtttttttcc cgggggctga ccccagcgtg cagatggttg ctgcacttgc cacgttctcc
    46621 gttccctttc tgattcgacc gcttggcggg ctcttctttg gtatgttggg cgataaatat
    46681 ggtcgccaga agatcctcgc tatcactatt gtgattatgt cgatcagtac gttctgtatt
    46741 ggcttaatac cgtcctacga cacgattggt atttgggcac cgattctgct gttgatctgt
    46801 aagatggcac aaggtttctc ggtcggcggt gaatataccg gggcgtcgat atttgttgcg
    46861 gaatactcac ctgaccgtaa acgtggcttt atgggcagct ggctggactt cggttctatt
    46921 gccgggtttg tgctgggtgc tggcgtagtg gtgttaattt cgaccattgt cggcgaagcg
    46981 aacttcctcg actggggctg gcgtattccg ttctttattg ctctgccgtt agggattatc
    47041 gggctttacc tgcgccatgc gctggaagaa actccggcgt tccagcagca tgtcgataaa
    47101 ctggaacagg gcgaccgcga aggtttgcag gatggcccga aagtctcgtt taaagagatt
    47161 gccaccaaac actggcgcag cctgttgaca tgtattggtc tggtaattgc caccaacgtg
    47221 acttactaca tgttgctgac ctatatgccg agttatttgt cgcataacct gcattactcc
    47281 gaagaccacg gggtgctgat tattatcgcc attatgatcg gtatgctgtt tgtccagccg
    47341 gtgatgggct tgctgagtga ccgttttggc cgtcgtccgt ttgtgctact tggtagtgtt
    47401 gccctgtttg tgttggcgat cccggcgttt attctgatta acagtaacgt catcggcctg
    47461 atttttgccg ggttactgat gctggcggtg atccttaact gctttacggg cgttatggct
    47521 tctaccttgc cagcgatgtt cccgacgcat atccgttaca gcgcgctggc ggcggcattt
    47581 aatatttcgg tgctggttgc cggtctgacg ccaacactgg cggcctggct ggtcgaaagc
    47641 tcgcagaatc tgatgatgcc tgcctattac ctgatggtag tggcggtgat tggtttaatc
    47701 accggcgtaa ccatgaaaga gacggcaaat cgtccgttga aaggtgcgac accggcggcg
    47761 tcagatatac aggaagcgaa ggaaattctc gtcgagcatt acgataatat cgagcagaaa
    47821 atcgataata ttgaccacga gattgccgat ttgcaggcga aacgtacccg cctggtgcag
    47881 caacatccgc gaattgatga ataagctgaa acggatggcc tgatgtgacg ctgtcttatc
    47941 aggccaattg aactcttaag gttcacttaa tctctgacgc gcatactctc ctccaggtta
    48001 acggaggaga gtgcaatgaa aaaccgtgtt tatgaaagtt taactaccgt gttcagcgtg
    48061 ctggtggtca gcagctttct ttatatctgg tttgccacgt tctgatcttt cttcagccgt
    48121 acccaggccc gcgtgccgga agtctcttgc cggttttgca ggaaaaactg cccgtgatgc
    48181 aactgtgtaa tgcggctgac aatacttaac cccagaccaa tcccgccata acggctgtcc
    48241 atacgtacaa acgctttact caactccccg catttactct catcaatacc tggtccttca
    48301 tcttcaactg ccatgaccgc tccgtcatct tcttgcagct taatcataat gttgctgcct
    48361 tgcgggctgt aacgatgggc gttttctacc aggtttcgca ataacatccg cagcagggtt
    48421 gcatcaccct gaacggtgat gtcggcggcg ctctctggca atagcagggt ttgctgtcgc
    48481 tggtcgagca tggtactgag ttcgtcatac gaggggagaa tgacatcttc cagcagtttt
    48541 acatgttgat aattaccgga agaaaatgac tgtccggcac gcgccagttg cagcagctgg
    48601 gagacgctct ccatcatctg atcaagtcgt gccactaacg gtgctacatc aatgtgatgc
    48661 gttttcgcca gcagttccag atgcaaacgc acccccgcca gtggcgttcg cagttcgtgc
    48721 gcgacgtcag cggtaaacaa cctttcgtta tccagcgtgc tggtcaggcg actgaccaga
    48781 tcgtttaacg ccgaaaccac cgcttcgatt tcgagggtgg cgctgtgaat ggcaatgggc
    48841 gttaagttgt cggcagtgcg cgcttccagc tctttttgca gctccgccag cgggcgggtg
    48901 atgcggcgca ccgcctgata gcagataaat agcgtcaggc tgaccataaa gacgccgggg
    48961 acaatcaggc tggcgaccgc ctcgcggatc tcacgcatga tgtggcgatc gttgttgcga
    49021 ttgtcgcgta gcgcctgctc aaacagctga atctgctcgg tactttcatg ccatagccag
    49081 aagacgctga tcagctcaaa caccaacaaa atggccccga tggtcaatat cagccgttgg
    49141 cgcagcgata ttggtcggcg cagaaaatgc atcagattca attagttttc ctcattcgcg
    49201 accagcatat agccaaagcc gcgcacggtg cggatacggg ctttgcccac tttgtcgcgc
    49261 agattgtgga tatgcacttc cagggtgttg gtcgagggtt cattgtccca gttatagatg
    49321 tcgttgtaga gaatttcccg atgcaccgga ctgcctgctt tgagcattaa ccgtgacagc
    49381 agagcatatt ctttgggcgt cagaatcaac tcttcaccgc ccatccatac ctgacggcga
    49441 cccatattca gcgtcagatt gccaacaatc agctcacttt cgccctgatt attatggcgt
    49501 cgtagcaggg cgcggatacg ggcgtgtaac tcttccagcg caaaaggctt caccagatag
    49561 tcatcggcac cgacatccag cccagcgatt ttgtcggtca gcgtatcgcg agcggtgagg
    49621 atcagtactg gcagggtgta ttttttctgc cggatacggg cgagaaaatg cagtccatct
    49681 tcgtcgggta accctaaatc cagtaccacc aggctgtaat gaccggcctc aaggctttgt
    49741 tccgccatcc gcgcggttgt cacgccatcg cacgcgtagc cttcagtttg cgccgccaga
    49801 atcaatccct gcaataacag cgtatcgtct tcaacaatca gaattttcat tcactcactc
    49861 tcctgcaagt ttgcagaata tcatccgcag cctggtaata cttcgtctca acgccagtta
    49921 atcccaatag cgtggagaat aaattgtctt gtgaatagtg ttgcgtttgc gcctgttttt
    49981 gcaggcagtt ctggtcaacc tgataccgtt tttgataatc ctccgacagc cacagcagca
    50041 tcggcacctg tttttggcta tccggggcga tggcataagg cagaccgtgc agatagatgc
    50101 cattttcacc taacgattca ccgtggtcag aaagataaac caggctggtg gtaaatttat
    50161 cctgatgttc tttcagcaga ttaatcgctt tatcaacaat atagtcgacg taaaccagcg
    50221 tgttgtcgta agtgttcacc agttgctctt tgctacaggt ctggatctca ttggtgtcgc
    50281 aggttggggt aaatttcctg aactgcggcg gatagcggtt gtaataggtc ggaccgtggc
    50341 tgccgatggt gtgtaagaca atcacgccat caccctgcag gttattgatg tactcttcca
    50401 gcccgtggaa cagcacttcg tcatagcatt cgccgttgat gcactgacca ggcagattca
    50461 gcgcggtgac gttctggtga ggcacgcggt cgcaggcacc tttacagccg ccatcgttgt
    50521 cattccacag cacgttgatg cccgctcgct gaatgatatc cagcacgcct tcctggtgct
    50581 gtgccagctc ttctttgtaa tgctcacgcg gcatatccga gaacatgcac ggtactgaaa
    50641 ctgccgttgc cgtgccgcaa gatgcggtat tagggaaata gaccacgtta tctttcgcca
    50701 gccgcgggtt agtttcacgc gggtagccgt tgagggagaa gttctccgcc cgcgaggttt
    50761 cgccgacaat caggatggtc aaatttttac gtttttcgtt ctgcattaac gggttgcggt
    50821 gggcgtcttc accaattcgc accagcggta gatttgccag tcgctgatgg gagtaccatg
    50881 accagctggc aacaatgctg ttagaggggc ttaaggattt caccagctct ttgttattgc
    50941 ggaacaacga ggcgtagtct ttataaaaca gtgcggcgac cagcaaaatc agtagtacag
    51001 aaaccagaat attggctcca cggaaaagaa cactgcgcag acgcgaggtg gcaggtttga
    51061 tttttatcca gcaggcaatc agcgcagcaa gcacgccgct gaatcccagc gttaataaca
    51121 tttgcggtgt catcagcgca taactttctg ccggagtggt atcaataata ttggcaatca
    51181 tcgagcggtc gatgacgatg ccgtaagtca ttatgaaata ttgtgcagcc gcgccaacca
    51241 gaataaacag gcaggccagt ggtcgattaa gccataagaa agagcttagt gtcaggacaa
    51301 tattaatcac gctgaaagcg acgaccggca tcgacaagaa aaccagtacg ttatgcagcg
    51361 aatccagcgg cagcgcctgc aacacctgtt taaaaaaggc aatattcagg cagatagaga
    51421 tataaaaagc ggccaacaat agccaggcga gtaaattcaa agagggtctt tttagtaggc
    51481 gcttcaacat cacggtgttt ccatcgaaca aagtgcgcat atgctcgcaa agcaaaatta
    51541 agccaacctt aagttcttaa ggttggcttt tatgtttgct ggattaaggg gaattaatct
    51601 ttgcttattg gtgcatctaa gggatacggg tttttatgta gccggttgta attcagcgca
    51661 tacatggcgg tgatgaccat cagggtgaca aatgaccaca taacctcttt cgctccggac
    51721 cccaccacgg cccagatgca gtagaggaag gcaatggtag taactgccag atatgccggg
    51781 cgtgctttac caaagtgacc gtgtccgagc agcagtaacg ccgcacaggt gtaaagatat
    51841 ggcaccagtg taaagatgac cgagacggaa gaaaccagac cgaactcttt ggtcgcgttt
    51901 ggtgaaatgc tgctgagctg gaatatggtc atcaaaatac cgacgataat cagccccgcc
    51961 actggcgtac ccgctttatt tacacgggca aaaatcggtg ggaacagtcc gtcatcggca
    52021 gcggctttcg ccgtttgacc cgccagcaac gtccagccgc ccagtgaacc taagcaaccc
    52081 gcagctgcgc agaaggaaac aatggccccg gcggtgtcac ccaacgccat ccgtgcggca
    52141 tcaccgaatg gcgaagcaga aacgcgcagt gcggcattag ggatcatccc cataatcgcg
    52201 gtggtagaaa gtacatagca aacggcggca atcaataccc caccaatggt ggcgataggg
    52261 acattgcgtt tcgggttttt caccacacct gcggcaacgg aggcactttc cacaccgatg
    52321 aacgaccaca gcgtaacgtt aagggtactt tgaattgcac cgaaggtgcc caggccgctg
    52381 acgttccatg ccgccatata ggtttcacca cggaaccaga accagccaaa tacggcaatc
    52441 ccgacgatgg ggatcagcgc cagcacggtg gcaactgcct gcacacgggt gatcattttc
    52501 ggaccgacaa tgttcagcag gacgaagatc cacagcacca cgacgcaggt gatggttaat
    52561 accaatggat ctttcagaat cgggaagaag taacttaaat atcctacgcc aatgaccacc
    52621 atggcgatat tgccgatcca gcaggccagc cagtagagga cgttggtttg ataaccgaga
    52681 aacgggccaa agcagcggcg ggcgtaagcg taagaaccac caggacttgg atcgaggaac
    52741 gacattttgg cgtataccat cgagagcccc agcgcaccga taatcgtcac caaccatcca
    52801 taaatggcaa tcccgccagt cgaggccagg tttgcaggta acagaaaaac acctgacccc
    52861 ataatattcc ccgacaccat cagggtgacg gggattaagc ccactttgtg agcatcagca
    52921 tccgaagaca taattaaact cctgcgaagg cgagcttcgt gacaataaat tacgtcatat
    52981 catacgcctg cattcgatag ttgaattatt atcgaccggg ttatcgctga tgccgttatt
    53041 aatatagctc ttcgttaagg ttaaaaatca ggcgacagtg cgttctctgt gctgactaac
    53101 ataatgcagc ggcgtcatac cgtagaagtc tttaaagaca gaaataaagt acgacgtact
    53161 gttgtagccg caggactgtg atacctgaga gatattttta ccgtccatca ttaattcatt
    53221 tacggcataa cgcatgcggc aggtggtgat tatttggcta taactggtgt tttcgctttt
    53281 caactttttc tttaacagac ttgggctaag acataaacaa ctggctacca tactaagatt
    53341 ccagtctttg tgaatatcgc tttcaataat ttgataaacg ctgtcactta cacaattacg
    53401 taacatatac atcattaatg aaaggaattt tttactgtcg agaaaacggg atagcaccgt
    53461 gaataataat gcgcgtgttc gttccttttc tgactcagtt tctgcgggca tcatgctgtg
    53521 ttgcgcggca acgcgaaaga cgtctggcgt caggcatggc agggtgagta tgggcgtagc
    53581 gctacgttgc catactggta tttgcgagag atctttattc agaaaccgga ggtaatcttt
    53641 gatgatgtcg tgactaatat gagcaaccaa agtgttgtta agagaggaga cgtcgataat
    53701 attattttca caatttaata acgccatatg gttagcttta aggctaatag gttctttccc
    53761 attcaccctt atccagacat ctttttcagt caataaaaca atacaaggtt ggtcgctgca
    53821 aatcctcata catgtactcc tgagtgcgaa taaaagacca gttctcgcta aagcaaagcg
    53881 ataccgggaa atggttatat aattgtatga tgaatataaa catgcataaa aataacgagt
    53941 tttactaata ttacaaattt ttatagtaat ttctcatgta catatttttt tacaggataa
    54001 ataacaggca aaaaaaagcg cggggtgggg ccgcgcaaaa agtatgacat ttttgtttgc
    54061 agcaattttt atgaaaacgt tgccatactc aaaaggccta aggccaggcg gcgtaatgtt
    54121 atttaaacaa ttacgccttc agcggaatag tggttacgct ttcacgcaca taacgtggta
    54181 aataccgtca ataatttcag tcccttcagt ttcgtgttca aatccaggga aatggtggtc
    54241 ccaggattgc agcgagcgta aataacttac ttgcggactg tttttatcgc cgaagttttc
    54301 accagacagc agcatcggga ttcctggcgg atacgggata actgagtttg ccgcgatgcg
    54361 tcctggcaga ttttcaatgg ataccagttc gacattgttg tcgacaatcg cgttgtacgc
    54421 ttcacgcggg gtgacttccg ccaccggcag gccggaatag gcttcgttca accgtgcgcc
    54481 agggttgttt tctttcagcc aggcaaacat ggtgtcaccc agatcgtgaa tccccatgtt
    54541 cgcgtaagtg tcaggatatt gttcaacaag ttccggcatc acctgcgcca gcggtgtgtt
    54601 ggcgtcatag tggcgtttga aggagcaaag ggtgttaacc agagttcccc atttcccacg
    54661 ggttacgccc atagagaaca ggaacataat ttggaagtca gtggtgcggg taggtacaat
    54721 gccgtggcga ccaagccagg cagtgaccag cgccgccgga acaccggttt cttccagttc
    54781 accatcttca cccattcccg gagcaaggat gctgacttta atcgggtcga gcatactcca
    54841 gttatccgga atatctttga agccgtgcca gctttcgccc ggatgcatta cccagcagtc
    54901 ctgaacggtg gtcagcagtt tggttggtgc gtcagcaaag tcataggttt tgccggtttg
    54961 tgggtcggtg acgacttctt tgttccacgg tttgaagaac cagctaccgt cagcggtgaa
    55021 ctctttatat agccgcgcca tcgcctgacg gaaatcaacc gcttcgtcaa tcacttcctg
    55081 tgtcagtgac aggccgctgt tgccgtccat catcgacacc gccacgtcgt tggatgcgca
    55141 gatggcatac agcggggagg tggtggcatg catcatgtag gcctggttga agcgggagaa
    55201 gttaatcgcc ccacgacctt cacgtacatg aatataagaa gcctgtgaca gcgcattcag
    55261 cagtttgtgg gtggagtggg tggcgaaaac ggtaggaccg ttgtgatcgc caggttcgcc
    55321 gcgcatggca tagtgatcgg catagatcgg gttgaaacgt gcatagccgt accaggcttc
    55381 gtcaaagtgc agacgatcgg aggttttttc cagcagatcc tgcgcttctt tagcgttata
    55441 acacacgccg tcataggtgc agttggtcac cacgcagtaa gacggttttt gcccggcttt
    55501 gtctttggtc agcgggcttt cactgatttt cttctgcaag gtttcaggtt gcatttcctg
    55561 cggatagatt ggcccgataa tgccgtagcg gttgcggctt ggcaccatat agaccggttt
    55621 cgcgcctgtc agcatcaaac cttgttcgat ggatttatgg cagttacggt caacgaccac
    55681 gacatcgtta tcggtcatgc aagcctgcat gatggtgcgg ttagagccgg aagtaccgac
    55741 gactaccgac caggagcgat cggcaccaaa tacgcgtgcg gcatattttt cgctttcgcc
    55801 aaatgcgcca gtatggtcaa gcaaagaacc gagggaagtt cgttcgatgc ccatgtcggt
    55861 gcggaacaga ttttcaccat agtagtcatg gtagaaacgt ccggcgggtg ttttggtaaa
    55921 accaacgccg ccctggtggc ctggcgctgc ccaggaatat tcatggatgt cactatattt
    55981 catcagcgcg ctgaacagtg gcggcaacag ctgctggcgg tagcgggtca tcgcggcaac
    56041 ggcgcgtccg gcgataaagt cggcggtatc ttccagaatc caggcgaatt catcgacaag
    56101 ctccagcagg tcgcgatcca ttgcggcgag ggctttttcc cgatcgccca acaggaagac
    56161 cggcacgttt tgttggcgct catgaagctt accgatcaat tgtctgacgt tttgatgttc
    56221 gtccggatgt tccatttgat agctgaacat caggcagtca atggcttcgt ttgaagagag
    56281 aatggcaaaa ccatcatcaa aggaggtgga tttaatcacg gtaacatttt gctggcttaa
    56341 agcatctgcc agacgctcaa cggcgttacc gacccaggtg tcttgatgga gaaactcgct
    56401 ttcaacaatt aatactttca tcattgctta cccggttatg aaggaatctt cgttgcgggc
    56461 aagtatcttc cggccttttc gggctgtaaa gcgcgtgaaa aacaaacatt tttgaaatat
    56521 ttatttttat aaacaatgcg ttatgtgatt attttaaatt attttcactg cttattatcg
    56581 acggctaaac tatttttttg gctgatactg atatcgtctt tagccgggaa acgtctggcg
    56641 gcgctgttgg ctaagtttgc ggtattgttg cggcgacatg ccgacatatt tgccgaacgt
    56701 gctgtaaaaa cgactacttg aacgaaagcc tgccgtcagg gcaatatcga gaatactttt
    56761 atcggtatcg ctcagtaacg cgcgaacgtg gttgatgcgc atcgcggtaa tgtactgttt
    56821 catcgtcaat tgcatgaccc gctggaatat ccccattgca tagttggcgt taagtttgac
    56881 gtgctcagcc acatcgttga tggtcagcgc ctgatcatag ttttcggcaa taaagcccag
    56941 catctggcta acataaaatt gcgcatggcg cgagacgctg tttttgtgtg cgcgcgaggt
    57001 tttattgacc agaatcggtt cccagccaga gaggctaaat cgcttgagca tcaggccaat
    57061 ttcatcaatg gcgagctggc gaatttgctc gttcggactg tttaattcct gctgccagcg
    57121 gcgcacttca aacgggctaa gttgctgtgt ggccagtgat ttgatcacca tgccgtgagt
    57181 gacgtggtta atcaggtctt tatccagcgg ccaggagaga aacagatgca tcggcagatt
    57241 aaaaatcgcc atgctctgac aggttccggt atctgttagt tggtgcggtg tacaggccca
    57301 gaacagcgtg atatgaccct gattgatatt cactttttca ttgttgatca ggtattccac
    57361 atcgccatcg aaaggcacat tcacttcgac ctgaccatgc cagtggctgg tgggcatgat
    57421 atgcggtgcg cgaaactcaa tctccatccg ctggtattcc gaatacagcg acagcgggct
    57481 gcgggtctgt ttttcgtcgc tgctgcacat aaacgtatct gtattcatgg atggctctct
    57541 ttcctggaat atcagaatta tggcaggagt gagggaggat gactgcgagt gggagcacgg
    57601 ttttcaccct cttcccagag aggcgagggg agcgtccgag catcatgagg ccgaaaactc
    57661 tgcttttcag gtaacttatt accataaact cagatttact gctgcttcac gcaggatctg
    57721 agtttatggg aatgctcaac ctggaagccg gaggttttct gcagattcgc ctgccatgat
    57781 gaagttattc aagcaagcca ggagatctgc atgatgactg cacccaaaat tacatttatc
    57841 ggcgctggtt cgacgatttt cgttaaaaat attcttggtg atgtgttcca tcgcgaggcg
    57901 ctgaaaacgg cgcatattgc cctgatggac attgatccca cccgcctgga agagtcgcat
    57961 attgtggtgc gtaagctgat ggattcagca ggggccagcg gcaaaatcac ctgccacacc
    58021 caacagaaag aagccttaca ggatgccgat tttgtcgtgg tggcatttca gattggcggt
    58081 tatgaacctt gcacggtgac tgatttcgag gtctgtaagc ggcatggtct ggaacaaacc
    58141 attgccgata cgttggggcc gggcggtatt atgcgcgcgc tacgtaccat tccgcatctg
    58201 tggcaaattt gcgaggacat gacggaagtc tgccccgatg ccaccatgct caactatgtt
    58261 aacccaatgg cgatgaatac ctgggcgatg tatgcccgct atccgcatat caaacaggtc
    58321 gggctgtgcc attcggtgca gggaacggcg gaagagctgg cgcgtgacct caatatcgac
    58381 ccagctacgc tgcgttaccg ttgcgcaggt atcaaccata tggcgtttta cctggagctg
    58441 gagcgcaaaa ccgccgacgg cagttatgtg aatctctacc cggaactgct ggcggcttat
    58501 gaagcagggc aggcaccgaa gccgaatatt catggcaata ctcgctgcca gaatattgtg
    58561 cgctacgaaa tgttcaaaaa gctgggctac ttcgtcacgg aatcgtcaga acattttgct
    58621 gagtacacac cgtggtttat taagccaggt cgtgaggatt tgattgagcg ttataaagta
    58681 ccgctggatg agtacccgaa acgctgcgtc gagcagctgg cgaactggca taaagagctg
    58741 gaggagtata aaaacgcctc ccggattgat attaaaccgt cacgggaata tgccagcaca
    58801 atcatgaacg ctatctggac tggcgagccg agtgtgattt acggcaacgt ccgtaacgat
    58861 ggtttgattg ataacctgcc acaaggatgt tgcgtggaag tagcctgtct ggttgatgct
    58921 aatggcattc agccgaccaa agtcggtacg ctaccttcgc atctggccgc cctgatgcaa
    58981 accaacatca acgtacagac gctgctgacc gaagctattc ttacggaaaa tcgcgaccgt
    59041 gtttaccacg ccgcgatgat ggacccgcat actgctgccg tgctgggcat tgatgaaata
    59101 tatgctcttg ttgacgacct gattgccgcc cacggcgact ggctgccagg ctggttgcac
    59161 cgttaaaacg cgactaaacg ctactgcgcc gggggattta ttccggcgca cacctctgac
    59221 gataccaata acagaaggcg ggcgttggta acagcgaccc gataccctat gagcatttca
    59281 atgactacaa aactcagtta tggatttgga gcgttcggga aggattttgc gatcggcatt
    59341 gtgtatatgt acctcatgta ttactacacc gatgtcgttg ggctgtctgt gggtttggtc
    59401 ggtactttgt ttctggtggc gaggatctgg gatgctatta acgatccgat tatgggatgg
    59461 attgtaaatg ctacgcgatc gcgatggggt aagttcaaac cctggatcct gatcggtacg
    59521 ttggcaaact ctgtaatctt atttctcctc tttagtgcgc atctgtttga aggtactact
    59581 cagattgtct ttgtttgcgt gacctacatc ctctggggca tgacttacac cattatggat
    59641 attcccttct ggtcgctggt tccaaccatc acgctcgata aacgtgagcg cgaacaactg
    59701 gttccttatc cgcgtttttt tgccagtctg gcaggctttg ttacggcagg tgtgacgcta
    59761 ccatttgtta attatgtcgg cggtggcgat cggggatttg gctttcagat gttcactctg
    59821 gtactaatcg ccttttttat tgtttcaacc atcatcactc tgcgcaatgt gcatgaagtc
    59881 ttttcgtcag acaatcaacc gtctgctgaa ggaagccatc tgacacttaa agccatcgtt
    59941 gcgctaattt ataaaaacga tcagctttca tgcctcttgg gtatggctct tgcttataat
    60001 gtagccagca acattattac cggatttgct atctattatt tctcatatgt tatcggtgat
    60061 gcggatttgt tcccctatta tctgtcgtat gcgggagctg ctaacctggt gacgttagta
    60121 ttcttcccac gcttagttaa atcattatcc cgacgcattt tatgggccgg agcatctatt
    60181 cttccggtgt taagctgtgg tgttctcctg ttaatggcat taatgagcta tcacaacgtc
    60241 gtcctcattg tgattgcggg tattttgctg aatgtgggaa cggcgctttt ctgggtatta
    60301 caggtcatca tggtggcaga taccgttgat tacggtgaat ataaactgca cgtacgctgt
    60361 gaaagtatcg cttactccgt gcagactatg gtggtgaagg gcggttcagc ctttgcggct
    60421 tttttcattg cggttgtgtt agggatgatt ggctatgtac cgaatgttga acagtctacg
    60481 caagccctat taggtatgca gtttattatg attgctctac caactctgtt tttcatggta
    60541 acgctgattc tctacttccg tttctatcgc ctcaatggcg acacgctgcg caggatccag
    60601 attcatctgc tggataaata tcgcaaagta ccgcccgagc ctgttcatgc tgatattccg
    60661 gtcggtgcag tgagtgatgt gaaagcctga cgtggacaat agctaacgaa aatggcctga
    60721 tgcgatatgt ttatcaggcc acgtcttaat gtaatgcttt ggatttgcaa attttgtaga
    60781 ccggataagg aattcacgcc gcatccggca tcaacaaagc gcacgttgtt atccggttat
    60841 caagccaaag cgccgtagct ggcggcaatg aaagcgagcg aggaatatca ccgtcgttaa
    60901 tgcgccaagc agcgcgcaga acatatcgga ttgcgtgtcc cactggtcgc cctgggtgcc
    60961 gagaaaatca tccgctccct ggcccattgc cagcgccgcc caccactcga ttaattcata
    61021 catcgcgctt atcgccagcg ccacgcagca gaccaggaac gccaccattt tacgtccgcg
    61081 cacgtacatc ccgcgcacga gaatttctcg tgccaccagt gcaggcacca gcccctggaa
    61141 aaaatgcccc agcttgtcat acggattacg gctcaacccc agccattcct gcacctcaaa
    61201 accgatgggg actttcgcgt aggtgtattg cccgccgacc atcaggatga tggcgtgaaa
    61261 gaaaatgagc gtatagagca gcggcgttaa cggataacgt ttagcggtgg caagcagtag
    61321 cggcacgaca ataatcaccg gtgtcacttc catcagccag gtgagtttgt catgggccga
    61381 aatgccggta taaatcagga ttaacgttag cgccagtgcg ccggtgttaa gaattaacgg
    61441 cttgagtgtg cgggtcatgg tgagttcgca agtcagggaa aatactgact attcaccagc
    61501 aagcgtgaaa ttacaatcgc aaaagaggtg gcccaggggg atcacctggc agcatgctgc
    61561 caggcgctgg gccgaagagg ttacttagtg cagttcgcgc actgtttgtt gacgatctgc
    61621 tggaagaagt cgttaccttt gtcatcgacc aggataaacg ccgggaaatc ttctacttcg
    61681 attttccaga tagcttccat acccagctcc ggataagcga cgcattccag atgcttgatg
    61741 ctctgctgcg ccagtaccgc cgccggaccg ccgatgctac cgaggtagaa gccgccgtgt
    61801 ttatgacacg cgtcggtaac ctgctgactg cggttacctt tcgccagcat gatcatgctg
    61861 ccgccgtggg attgcagcag atccacgtag gagtccatac ggcctgcggt ggttgggcca
    61921 agtgaacctg atggataacc ggcaggggtt ttcgccggac ccgcgtagta gatcgggtga
    61981 tctttgatgt actgcggaag ttctttaccg gcgtcaatca gctctttcag cttggcgtgt
    62041 gcaatatctc ggcccacgat aatggtgccg gtgagcgaca aacgagtgga taccgggtat
    62101 tgcgaaagct gggcgaggat ctctttcatc gggcggttaa ggtcaacttt caccgcttcg
    62161 ccttcaccgg cctggcgcag ttcttgtgga atgtactggc ctgggttgtg ttccagtttt
    62221 tcgatccaga taccttcgcg gttgattttc gctttaatgt tacggtcagc ggagcaggag
    62281 acgcccatgc cgaccgggca ggatgcgccg tgacgtggca gacggataac gcgaatgtcg
    62341 tgcgcgaagt atttaccgcc aaactgcgcg ccaagaccga gtttctgggc ctcttccagc
    62401 agttcctgtt ccagctggac atcgcggaac gcctgaccat gttcgttccc ttccgtcggc
    62461 agttcatcgt aatagtgagc gcttgctaac ttgacggttt tcaggttggt ttccgcagac
    62521 gtaccgccaa tcacaaacgc gatatggtac ggcgggcagg ctgcagtacc gagggtacgc
    62581 attttctcga cgaggaagtt tttcagtttg ccgggagtca gcagggcttt ggtttcctgg
    62641 tagagatacg ttttgttggc agagccgccg cctttcgcaa cgcaaaggaa tttgtactca
    62701 tcgccatcta ccgcgtacag gtcgatttgc gcaggcaggt tagtgccggt gttgacctct
    62761 ttgtacatgt ccagcgccgc attctgtgaa tagcgcaggt tatcttcgat ataggtgtta
    62821 tagacgcctt tcgacagcgc ttcttcatca ccgccgccgg tccacacgcg ctggcctttt
    62881 ttaccgacga tgatcgcggt gccggtatcc tggcaggtcg gcagcacgcc tttggcggcg
    62941 atttcggagt ttcttaagaa ttgcagcgcc acgtacttgt cgttttcgct ggcttctgga
    63001 tcgtgaagaa tagccgcaac ctgtttctgg tgtgccggac ggagcatgaa agaagcgtcg
    63061 tgaaaggctt gctgcgccag tagggtcagg gcttctggtt ccactttcag gatggtttcg
    63121 ccgtcgaagt cggcaacgct aacgtaatcg gaagtgagta gatagtattc ggtattgtct
    63181 ttccccatcg ggaaaggtgc ctggtagata aagggtttgt ttgacatagc ttccagcctg
    63241 taactctgta tttgttattc gaaaatggcg tgccgcgtag tcacgggcgg cacgcaaagt
    63301 gcatttataa gaacccgtac atcgcggcga agatccagcc gaagacgcac gatacgctaa
    63361 caccaatcaa ccccggcaga ataaaactgt ggttgatgac gaagcgaccg atgtgggtgg
    63421 tgccggaacg gtcaaactga atcgctgcca gatcgctcgg ataagtcggc aggatgtaat
    63481 aaccgtagca agccggtgct gaagccacga tgtatgccgg atcaacgccg atcgccagcg
    63541 cgaccggaac aatcgccgcc agcgccgcag cctgagagtt tacaaacttg gaaaccagca
    63601 gcagaacaat ggcatacgcc cacggatact ctttcaccat ttcacccagt acgccctgaa
    63661 tttcagacat atgcgcaccg aacatggttt ctgccatcca tgcgataccg tacaccgcca
    63721 cgatggcgat cataccggaa cggaagactt cgttttttga gatagacgcg ggattggttt
    63781 tggtcaggat aataatcagc gccccggtca gcagcataaa catctgaata accagtacca
    63841 tcgacagcgg tttgccgccg aaggatggac gcaggtccga atcagcacca agaagggcga
    63901 ctacagcgat tgccccgagg aaaatccaca ttgccagcca gttgcttttc ggcagttttt
    63961 tatcgagcag cgtcgcggta tcaccgtaaa catactcacg gttttccggt acggagatga
    64021 atttctggaa ctcttcgtct ttatccagat ctttaccgcg gaaccagctg aagataccga
    64081 tcgccaggat accgattaac gtcgatggaa tggtgattgc cagcaggtcg aggaactcaa
    64141 gatggcgacc atcaaaggtg acattaccca gcattgcaac cagagacacg accgcaaccg
    64201 acaccggact ggcgataatc cccatctgtg caccgataga acttgccgcc atcggacgtt
    64261 ccggacggat gttgttctta atggcgacgt cgtagatgat cggcagaatg gtgtaaacca
    64321 catgacccgt accgcaaaga atggtcagtg tacaggtcac aaacggcgcg acaattgaga
    64381 catatttcgg gttgcggcgc agcagcttct cggcaatttg cagcatgaca tcaagaccgc
    64441 ccgaagcttg caaggtcgcc gatgccgcca ccaccgcaat gataaccagc atgacatcaa
    64501 ccggtggttt acctggctga aggtggaaga cgaagaccag aatgaccaga ccgataccgc
    64561 ctaataaacc cagcgcgata ccaccctttc tggcaccata aaacagacat atcagtatta
    64621 tgataagttg gatagtaaat aacatgtgtg aaccctcgcg ataatcctat ttaaattttt
    64681 gctgaataga tcacagtcac gttctgtttt gtatgaactg ttttcagagc ctgactaaat
    64741 atccgtttgg tcgttaccgg ctttagcaaa tacctcacag taaatattgg ctgattaaag
    64801 cagcggcaaa tttatgcact gtgataagcg gctttttcag agagaaaaac tctctggcga
    64861 tgggtttata gtttgtactg cgcagatgtt aatgttttgt ttgctgttat cttattgata
    64921 tttatcggtc tattttttgt tctcagggca gatatcatta ggtttaaaga ttaatctgat
    64981 ctacccattt gtgggtaaaa atacacataa tgcgggtgac ataatagtta attaactttt
    65041 gttatcgttt tgaaattaaa aacaccgttc acctgaagag atattaattt ttagcgatga
    65101 tggagggata attatatttg atctggcaca agttttactg atgaaggatg taacttgtgc
    65161 caggggtatt ttgcattacg gtaataatta ttacttacag ataaccagcg atccgttatt
    65221 ggcaatattg tttcagtagt gagtagtgtt ctgcctgaat acggtaacgg taaaccggac
    65281 gccccgtgac gccataatgg atactggtga acaagatgtg gcagttgacc agccagatga
    65341 ggtatttacg gcaggaaaca cgcgagatgt taacctcgtt agccagctcg tcggttgaaa
    65401 actcatagtc ctgatgcgcg tcaatccact ggcacagcgt gcgtaacgtc tgcggcgtta
    65461 agccttttgg caagcgacga ggatcctgtt cgttggagct gctgccgtgg attagctgat
    65521 caagctcggc ctggtcataa tactgatgtt tttccagcgc cattttcttt tgccgccagc
    65581 cggtgagcgc ctcttcaaag cgggaagcct ggaagggttt gatcaggtaa tccacgacac
    65641 cgtaatgcag cgaatcttta atggttgccg catcggctgc ggaggagatg acaatcacat
    65701 cacttttgca acgcgcgtta tgcaggacag gcagtaaatc gagcccgttc tctttttgca
    65761 tatagatatc gagcaatatc aggtcgatag gcgtatcgct attgaagata atctctttgg
    65821 ctttctccag cgtcgaggct gttccacagc attgaaagcc tgggatttgt gctacgtatc
    65881 ggcgattcag ctccgcgacc attgcgtcgt catcgataat taatacattg atcatctgtt
    65941 cgacctctcc ccgtcccagg gtatctggac aaaaaattgt gtgaaaatcc cgggttccga
    66001 ttccacggcg atgctgccgc cgagattttc tacctgttgt ttgacaagtg ctaaaccgac
    66061 gcctcgctcg cttccttttg tcgagacacc tttgtcaaaa atgtgatcga ttttgtcggg
    66121 tgcgatcccc ggtccatcat cgttaacttc gcagtgcagc cagccgtgac ggtagtgcaa
    66181 tgttacgcta atttcgccac cgggttccgg ccctaatgct tccagcgcgt tttctatcag
    66241 atttcccaat gtggtaatca gcgtcgcgac ctggtcctca ctgccgctgt ctggcagctg
    66301 gctttcactg tttaaaatca gcgtatggcc taaatcggtc gcgcggttaa tcttgctgat
    66361 taaaaaacca gcgataaccg gagatttgat cttacccagc agagagccaa tctcttcctg
    66421 atagttattg gctgttttga gaatgtaatc ttccaactgc ttataactct tcagatgcaa
    66481 taatccgaga atcacatgca atttattcat aaattcgtgg gatcgttcac gaagtgcgtc
    66541 agcatagttg accagaccat cgagtcgctg catcagttta cgtacttcag ttttgtccct
    66601 gaaggttgaa atggcaccga tgataacgcc attactgcgc accggaacgg tgttgatcag
    66661 taatagccga tctttaatcg taatctcttc gtcgcggcgc ggcgtaccgt cgcgtaacac
    66721 ttccgagaca tctaccacct gtgaccatga gtggctgagc gtcgacagtt tctcatcgtc
    66781 ctgcgactta cggtaattca gcaattcttg tgcggcatcg ttgatcagcg tgacctcgcc
    66841 gcgatcgtcc acggcaacga cgccttcttt gatagactgc aacatggcct ggcgctgctc
    66901 aaacagcgtg gagatttcgt agggttccag gccgaaaagg atttttttca gtaccttaac
    66961 cagaatgcag gtgccaatca gtccgaccag catgccaaat aataccgacc agataatgct
    67021 ccagcgactg tcattgattt gttgggtcac gcggcttaac tcaaggccga tcgccaccac
    67081 gccaatttgt ttatgatttt catcgtagat gggggtaaat acgcgtaaag cctgcgccag
    67141 aaaaccgcga ttgatagcga cattttcttt gccattcagc gctttaagga tgtcatcacc
    67201 tttaaatggc tgaccaatac gctgggcttc aggatgcgag tagcgaagac tttgcatatc
    67261 ggtaacgaca ataaacagca gatcgttgcg tttgcgcacg gcttccgcga tggcctggat
    67321 tccgctctcc tgcggttttt tctgcaagcc ctgacggatt tccggcgagt cggcgagggt
    67381 acgcgccact gccagtgcct tgttggctag cccgtctcgc gtcatatcac tgatttgcga
    67441 gaagtaaatc agatgcacca ccaatagcac cgagaacagt accgcactga ccattaagat
    67501 cactgtggta ctcaatttca tcggacgttt gcgtaacatg cggtagggca atgaatgtct
    67561 catcagcttc cttgtgtgac aaatttctta agcattatct ctgatgaggc gggtaattca
    67621 aagggagtaa gaatgattgg ctatataggg gaagagactc tggcaacgga aactgccagt
    67681 gctgtatgaa gattccaggg ctatgcttat agcgataatc atactgatga gagagggaaa
    67741 gtcatggatc aggcgctact ggacgagggt tatcgctgtt ataccggcga aaagatcgat
    67801 gtctatttca acactgcgat atgtcagcat tctggcaatt gcgtacgtgg caacggcaag
    67861 ttatttaatc tcaaacgaaa gccgtggatc atgccggatg aagtcgacgt cgtcactgtg
    67921 gttaaagtga ttgatacgtg cccgagcggc gcgctgaaat accgtcataa ataagcgagg
    67981 gtaaaatgga aatacgcgaa ggccacaata aattttacat taatgacgaa caaggcaagc
    68041 aaatcgctga aattgtcttt gtgccgaccg gagagaattt agcgattatc gaacataccg
    68101 atgtcgatga aagcctgaaa gggcaaggga ttggtaaaca gctggttgcg aaagtcgtgg
    68161 aaaaaatgcg tcgggaaaaa cgaaaaatta tcccattatg tccatttgcg aaacacgaat
    68221 ttgataaaac gcgggagtat gatgatattc gcagttgatg ggagagtaca gagtcacgat
    68281 atttttcttg ctctccgcgg agtgatgcag gagagcatct gaagggtagg gggatgcaca
    68341 aagaatgggc agagagcgcg tttttttgtc ccaagtcatc ccctttactg agcaaaaaaa
    68401 agaatatctc ctatatgaga atcatcaatc ggggttaata agttttgcgt ccccagagca
    68461 ttcaatattg ataggagtca tattatggaa ggtaaaaaca agttcaatac ttatgttgtt
    68521 tcttttgatt atccatcatc ttattcctca gtgttcttaa ggttaagatc attgatgtat
    68581 gatatgaatt tctcctctat cgtggctgat gaatatggga taccacgaca attgaatgaa
    68641 aactccttcg caataacgac atcgttagcc gcaagtgaaa tcgaagattt aatcaggctt
    68701 aaatgcttag acttaccgga tattgatttt gacctcaaca ttatgacagt tgatgactat
    68761 ttccgtcagt tttacaagta gccaggaagg ataagaagaa cataaaaaat ggcactattc
    68821 tctaaaatat taatttttta tgtgattggt gtgaacatat cctttgtcat tatctggttt
    68881 atctcacatg agaaaacaca tattcgttta cttagtgcat tcctggtcgg aataacctgg
    68941 ccaatgagtc tgcctgtggc attacttttt tctctctttt aggagctgta gttgagtgga
    69001 cccgctggtt atcgtgaaac gaagcgtctc tcctcaaaac tggatttgcg gaacgacgaa
    69061 cgaagcagtc gcctgactgc ttcgttcatt aaagtgaaat ttatttctgt gggcgcatcg
    69121 ccgggaagag aataacgtcg cgaatagtat gactgtttgt aaacagcata atcattcggt
    69181 cgataccaat acccagacca gcggttggcg gcagaccata ttccagcgca gtcacgtaat
    69241 cttcgtcata gaacatggct tcgtcgtcac ctgcagcttt agcgttaacc tgttcctgga
    69301 aacgttcagc ctgatcttct gcgtcgttta attcgctaaa accattaccg atttcacgac
    69361 caccgatgaa gaattcaaaa cggtcggtga tttccgggtt aacatcatta cggcgcgcca
    69421 gcggtgacac ttctgccgga tattccgtaa taaaggttgg ctgaatcaga tgtgcttctg
    69481 ccacttcatc aaagatctcc gtgacaatac gtcccagccc ccagcttttc tctaccgtaa
    69541 ttccgataga ttcagctaat gctttagcag catcaaaatt atccaggtcg gccatatcgg
    69601 tttctggacg atattttttg attgcttcgc gcatggtgag tttttcaaac ggtttgccga
    69661 aatcaaacac atgctcgcca taagtgactt tagtggtacc cagaacctct tgtgccaggg
    69721 tgcggaacag ggactctgtc agttcaatca aatcgtggta atccgcatac gccatgtaga
    69781 gttccatcat tgtgaactca ggattatggc gaacagaaat accttcatta cggaagttac
    69841 ggttgatttc gaatacccgt tcaaaaccgc ctacaaccag acgtttcaga tacagctccg
    69901 gcgcgatacg caggtacata tctaaatcca gagcgttatg atgggtaata aacgggcgag
    69961 cagatgcccc acctggaatt acctgcatca tcggggtttc tacttccata aagccgcgcg
    70021 cgaccatgaa ctggcggata gcggccagaa tttttgaacg gacaacaaac gtttgacggg
    70081 atttatcgtt agcgatgagg tccagataac gttgacgata acggacttcc tgatcctgca
    70141 gaccatggaa tttatctggt aaaggacgta gtgcttttgt cagcaggcgt aactcagtac
    70201 agtgaatgga aagctcaccg gtttgcgtct taaacagcgt accgcgggca ccgataatgt
    70261 cacccagatc ccatttttta aactgatcgt tataaacacc ttctggcagg ctatctcttg
    70321 caacgtacag ttgaatacgg ccaccgacat cctgcaacgt tacaaaggag gctttcccca
    70381 tgatacgacg ggtcatcatt cggccagcaa ccgagacttc aatgtttaag gattccagtt
    70441 cctggttatc cttcgcatca aactcttcgt gcagctggtc agaggtatgg tcgcggcgaa
    70501 aatcattggg aaacgccaca ccttgctgac gtagtgccgc cagtttttcg cggcgatttc
    70561 tcagttcatc gttaaaatca atagcctcat tggctccccg tgtttcttgt tcagacattt
    70621 tggttcctct aaatccagct ttcaatttag cgtagataaa gagacagatc ggtacactgt
    70681 attatctgcc tcgactatta ataactcagt ttatcttatc gaaactaacg cttacctcaa
    70741 gttgatatca ctaataaata accatcaaaa tggtttaaat gacttattaa tctagatttg
    70801 ctagtgttat aaactgaaag ttaatttatt cataaccaat tgtttttacg acagttaatc
    70861 gttgctctcc tgtatcatat tcgtcggcgt gctaaacaga aaacgggtag caaaggccaa
    70921 tacgacgatg atcgcgacac aagccaacgt ccactctccc atctgagaaa agaatcgctg
    70981 gtaagctgca attgccatac cgctaatttg cgactctgtc gtctgctgtg ccacgacgcc
    71041 tgctagccag ttggcgaccg cgcctgttgc cagcatataa ataccggtta atacgccaga
    71101 cattttcaga cgcgtgattt gcgcaatcgc caccgggtca ataaagagtt cggcaaagcc
    71161 cattagcgcc aacccggata tcatcacgcc cattgacgct tgaccgtcag ccgctgcatg
    71221 tcgggcatca aatgccaaca acataaagcc acaagccatc agcagtaagc caaaggcaaa
    71281 cttcagccag acgcgcaatg ttgagttgcc gcggctttct ggcgacgcca gccaggccag
    71341 tacaacccca gcgagcatca ccgcaattgc attcaccgac tggaatagtg ctgtaggtac
    71401 ttcaatattg aatgcctgac gattcacaaa gcgatcgata aacaagctga tggtactgcc
    71461 gccctgttgt gccagtaccc agaacaatgt cccgacaaac atcaacaata caatttgcca
    71521 aagagcacgg cggtgttcgg ggaatttgac catcatgcgg gcaatgattt gtgcggcaat
    71581 gaggcaaacg atcgccagca aatatccgga ccagtcgttc tccagcagca gggtaaaaaa
    71641 tactggggct aaacagagca tcaccactaa ccagctccat accggtaagg caaatttgac
    71701 gctagtgagc gcttttttat ccatactacg cgtggactgg aaatgacgat gcccgcttaa
    71761 gaaaatcaac aaaccgataa acatgccgcc acccgcaagg gcaaagccaa catgccatcc
    71821 ataccactga gcagccaggc cgcaggcgat tggggcggcg atagaaccga tattgcccgc
    71881 agcatacagc agcgaaaaac cgccatcacg tcgatgatcg ttctcgtcgt aaagctcgcc
    71941 aagcaaacag ctgatgtttg atttgaataa accgtagcca caaataatga ttgccagcgc
    72001 cagatacagg ctaaaggttg aatttgtatc aatgcccagc accacatggc caagggtcat
    72061 taacagcgcg ccggcaatca ctgcagtgcg gttgccgagc aggcggtcgg caagccagcc
    72121 gccgagaata ggggtaacgt aaaccagaga agcatatgcg ctgaacaggc tgatggcatg
    72181 gttatcatca aaaccaagct gatgggtgag atagagaatg agtaaggcac gcatgccgta
    72241 aaaactgaag tactcccaga tttggatcgc cacgatatag tatatcgcgc gcggctgtga
    72301 gggtgttttc atgtgttctc cttatgagca aaaaagggaa gtggcaagcc acttcccttg
    72361 tacgagctaa ttattttttg ctttcttctt tcaatacctt aacggtatag cggccatcag
    72421 cctgacggta tgcaccgtga atatcggttt caaagcccgg atagtgagcg ccgatttcac
    72481 acagcatctg caggaactcc agaaccggac ggctttcttc ggtgatcatt tcacccggca
    72541 ttaccagagg aactcccggc ggatatggaa ggatcatatt ggcgttaata cgacctacca
    72601 tttcgtcgag gtaaacttct tcggtcatac cgtgcagctc tttctggaac gcagcatacg
    72661 gagtcattac catcgtcggc agcacttcaa atgcgcgata catcagatcc ggcagattgt
    72721 ggtgaacaat cagtttgtgg atattctgag ccagttcctg aatacgcatg ttttcataga
    72781 attcaggatc ttcacgatac agagacggca gcatgttttt cacacgcagg ttcaggtcga
    72841 acgcacgttt gaagtcagtc agagcacgca gcaggctcag tgctttggtc ttatcgatac
    72901 cgatgctgaa caggaacagc aggttatacg gaccggtttt ctcaacaacg atgccatgtt
    72961 cgtcgaggta tttcgccacg atgctggccg gaataccaaa gtcgctcatg gtgccgtctt
    73021 tttccatccc cggagtcagc agggtgactt tgatcgggtc aagatacatg tgctcgttat
    73081 cgatgttttt gaagccgtgc caggtgctgt cagaacgcag cggccagcat tcagtggtat
    73141 cgatatgatc cggctgccat acatcaaaga accagccatc agattccgtt ctcagacgtt
    73201 tgatctcttt acggaatttg atcgcacgtt caatggaacc gttgatcaga cgcttaccag
    73261 cattgccttt catcatcgcc gctgcggttt cagtggacgc cacgataccg tagtgcggag
    73321 aagtggtggt gtgcatcatg taggcttcgt taaaggtttc ttcgtttacg tcacctttaa
    73381 cgtggatcat ggaagcctga gagaacgccg ccagcagttt gtgagtggac tgggtttcgt
    73441 aaatcacttt cccttctaca cggccaccgc tcataccgca tttaccttcg taaatcggtg
    73501 agaagttggt gtaaggcacc cacgcggagt caaagtggat ggatttcaca tccagtgttt
    73561 tcttgataaa gtcggtgttg tacagcagac catcataggt agagttggta attacagcat
    73621 gtaccggcca ggttgcgttt ggtgtttctt tcacgcgctt agcaatggta gcgtgctgga
    73681 attcactctg tgggatacca ccaagaatac cgtaagcgtt acgggtcggg cggaaataga
    73741 ttggcgtaac atcgctcatc atcatcaggt gggtcagcga tttgtggcag ttacggtcaa
    73801 tcagaatggt gctgcctgct ggagcagagt acataccaac aattttgttc gcagtggaag
    73861 taccgttggt caccatgtag ctgcggtctg cgttaaagac gcgagcgata tactgttctg
    73921 cttctttgtg tggaccactg tgatccagca gagaacccag ttcagatact gaaatggaaa
    73981 tatcagattt catggtgttc ggaccaaaga aatcatagaa caggctacct accgggcttt
    74041 tctggaatgc agtaccgccc atgtgaccag gagtacagaa agtatattta ccttcacgaa
    74101 catatttaaa cagtgcttta gtcagcggag gcagaatagt gttgatatat tcgtcagtgg
    74161 tctgcttgat cttattagca atatcttcag cagcacccag cgcatattca aagaagctaa
    74221 tctgtaaacg caggtcattc aggcttacat cgagagtgga atacgtatta gcgaacgcgt
    74281 acaacggcag gttctcgttc attttgctaa tttcttcgca cagctcgaga ttatatttat
    74341 cccagtcaaa aataacgccg cacagacgcg cattgttttc gatcagtttt aataagtcgt
    74401 cacggtcgtt cgggtaaaca atctggaagt tcagacgttc aagcgcgcga tgaagttcac
    74461 ggatgggttc ttctttaaaa taaaccccca tgtgattcaa tattgcaata acgttcatag
    74521 tcatatctcc aggtaaaaaa ggcccctccc aacacatggg acaaaatgaa aggaggagcc
    74581 tcggaaaata cttttaatta atgtgcgtta gacgcggtgt ggttatccat tgagtggctc
    74641 tggcgctcgt gcattttgcg agcgtagaac atcaggataa tcaggctgac gatgaaggta
    74701 cctgccagct cgaaggagct tgcgcccatc agcgcgatga agcagaacac acaacccagt
    74761 acagagcaga tcaggctgac aaagttgcgg atgttaacgc cttcaaaacg aatcaggtca
    74821 acgcaagagt agaagtacgg cagcatagtc agcagtactg cgataccggt cagttcaccg
    74881 aacaggtcag atgctttacc accggcagag ttcatcagag tgatgaggat catcagggca
    74941 gtcattttca ctgcagccag cagcagacct tttttcggaa taccgttgct gtcgacttca
    75001 ccataaactt tcgggaagtt accgtcgtta gcggcacgta cacctgcctg gcctaccaac
    75061 atcatccagg agcccagaga agtcaggcac gcaaaggcgg tgaatgcaga aaccagcggc
    75121 gcagcccagt taccgaggat ggttgaagca ctgattgcaa acggagcacc ggaagctgcc
    75181 attacagaag atggatacat accggaaagc acctgagtcg cagcgatgta aacaatacct
    75241 gctaaaccag tacccagcat ggttgccagc ggaacggtac gtttcgggtt tttaaccata
    75301 ccagtactta ctgctgcgga ttcaacaccc acgaaggccc acaggcagag cagaatactt
    75361 ttaatgatcg catgaccatc agtggtatcc gcagtattcc agttagctgc ataagttgcc
    75421 gcatcaaacc aatgccagcc aacaatagcg gtcattacta ccggaataag aaccagcacc
    75481 agaccaatag tggttaaacg gcttacccaa gtaccgccga gcatatttac aaaggtaaat
    75541 acccagacga tagcaataca ggcgataccc gccggaacag gatcatttaa tactgggaag
    75601 aaggtggaaa gataagatac cgcggtaata ccaatcgcca ggttaccaat ccagttagca
    75661 tggtaataaa gaacacctgt ctgaaaacca aatgcagggg aaatttctcc ggcataagca
    75721 attgggccac cttgttgcgg gttttttgtt gccagtcggg catatacata cgccagcgac
    75781 attgcaccaa taatagagat aatccaaccc cagatagcaa taccaccgat acttgctagg
    75841 ttcgcaggta ataatgcaat accgctcccc atcatattac cggcaacaac accggtacag
    75901 gcaaatagcc cgatcttctt ggcagaactc atgctcttct cctaatttca tttttgaatt
    75961 tggagtccgg gtcatgatgt ataactattt cctgaccaga ccaaactggc gctaagaata
    76021 ctcacgaaaa aaggattaat cctaaagatt aggtgaaata acacaaaagt ttctgtaagt
    76081 gagaacttga ggttttttat taacacatca ggatcgcaag ttgatatcat gaaaagataa
    76141 acattcaatg tttacaatgg attgcgggat at
//
LOCUS       DAZUDJ010000015        73556 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.015, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000015 DAZUDJ010000000
VERSION     DAZUDJ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 73556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73556
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.015"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..159
                     /locus_tag="ACHY1N_001449"
     CDS             <1..159
                     /locus_tag="ACHY1N_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HFS4043782.1"
                     /translation="RTIVELGKAIDFDARTAIPFEGERHNALDDARYQAKYVSVIWQK
                     LIPSQADS"
     gene            232..483
                     /locus_tag="ACHY1N_001450"
     CDS             232..483
                     /locus_tag="ACHY1N_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family protein"
                     /protein_id="HFS4043783.1"
                     /translation="MSEVIMIVSPGKWVSEEQLIALKGIKKGTLKKAREKSFMEGREY
                     KHVAHDGMPWDNSPCFYNLEEIDRWIERQASARPRRHLA"
     gene            503..1798
                     /locus_tag="ACHY1N_001451"
     CDS             503..1798
                     /locus_tag="ACHY1N_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012601524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3596 domain-containing protein"
                     /protein_id="HFS4043784.1"
                     /translation="MREAEMKYPTGVENHGGKLRIWFVYKGVRVRENLGVPDTAKNRR
                     IAGELRASVCYAIKTGAFDYAKQFPASHNLEKFGEARQDLTIKELAEKFLALKETEVA
                     KTSLNTYRAVIKNILSIIGEKNLASSINKEKLLAVRKELLTGYQIPKSNYIVTQPGRS
                     AVTVNNYMTNLYAVFQFGVDNGYLADNPFKGISPLKESRTIPDPLSREEFIRLIDACR
                     NQQAKNLWCVSVYTGIRPGELCALGWEDIDLKNGTMIIRRNLAKDRFTVPKTQAGTNR
                     VIHLIKPAIDALRSQMALTRLSKEHIIDVHLREFGRTEKQKCTFVFQPEVSAKVKNYG
                     DHFTVDSIRQMWDAAVKRAGIRHRKSYQSRHTYACWSLTAGANPAFIANQMGHADAQM
                     VFQVYGKWMSENNNAQVTLLNTQLSEFAPTMPHNEAMKS"
     gene            complement(1986..3005)
                     /gene="rspB"
                     /locus_tag="ACHY1N_001452"
     CDS             complement(1986..3005)
                     /gene="rspB"
                     /locus_tag="ACHY1N_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HFS4043785.1"
                     /translation="MKSILIEKPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNV
                     CTTLAVLGVHADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTE
                     NDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPL
                     GEIFTEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKE
                     LSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEQDQKHCCKVL
                     LTFSE"
     gene            complement(3017..4231)
                     /gene="rspA"
                     /locus_tag="ACHY1N_001453"
     CDS             complement(3017..4231)
                     /gene="rspA"
                     /locus_tag="ACHY1N_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HFS4043786.1"
                     /translation="MKIVKAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYG
                     MSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGDKPGLGIEFDEKLAAKYPYEPAYLP
                     VARLEDGTLWNW"
     gene            complement(4437..4763)
                     /gene="ynfA"
                     /locus_tag="ACHY1N_001454"
     CDS             complement(4437..4763)
                     /gene="ynfA"
                     /locus_tag="ACHY1N_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HFS4043787.1"
                     /translation="MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIV
                     AGWGRT"
     gene            4898..5239
                     /gene="ynfB"
                     /locus_tag="ACHY1N_001455"
     CDS             4898..5239
                     /gene="ynfB"
                     /locus_tag="ACHY1N_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HFS4043788.1"
                     /translation="MKITLSKRIGLLAFLLPCALALSTTVHAETNKLVIESGDSAQSR
                     QHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVITP"
     gene            5274..5834
                     /gene="speG"
                     /locus_tag="ACHY1N_001456"
     CDS             5274..5834
                     /gene="speG"
                     /locus_tag="ACHY1N_001456"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HFS4043789.1"
                     /translation="MPSAHSVKLRPLEREDLRYVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQIIISPEYQGKGLATR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFSVEGELMHEFFINGQYRNAI
                     RMCIFQHQYLAEHKTPGQTLLKPTAQ"
     gene            complement(5837..6547)
                     /gene="ynfC"
                     /locus_tag="ACHY1N_001457"
     CDS             complement(5837..6547)
                     /gene="ynfC"
                     /locus_tag="ACHY1N_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HFS4043790.1"
                     /translation="MKYKLLPCLLAIFLTGCDRTEVTLSFTPEMASFSNEFDFDPLRG
                     PVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTVVALVLDANYYRDAET
                     LEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYDDQGYPLGKTTKS
                     NDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDSHANPVDCQLIIVDEG
                     VNPAVERVYTIKNTIDYY"
     gene            6655..6960
                     /gene="ynfD"
                     /locus_tag="ACHY1N_001458"
     CDS             6655..6960
                     /gene="ynfD"
                     /locus_tag="ACHY1N_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
                     /protein_id="HFS4043791.1"
                     /translation="MKLSTCCAALLLALASPAVLAAPGSCERIQSDISQRIINNGVPE
                     SSFTLSIVPNDQVDQPDSQVVGHCANDTHKILYTRTTSGNVSAPAQSTQDGAPAEPQ"
     gene            7159..9585
                     /gene="ynfE"
                     /locus_tag="ACHY1N_001459"
     CDS             7159..9585
                     /gene="ynfE"
                     /locus_tag="ACHY1N_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenate/tellurate reductase subunit YnfE"
                     /protein_id="HFS4043792.1"
                     /translation="MSKNERMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRSAAAAV
                     QQAREKVVWGACSVNCGSRCALRLHVKDNEVTWVETDNTGSDEYGNHQVRACLRGRSI
                     RRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYS
                     SGIVGGNMTRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTD
                     IENSKLVVMFGNNPAETRMSGGGITYLLEKAREKSNAKMIVIDPRYTDTAAGREDEWL
                     PIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGE
                     GDDNTAKTPQWASQITGIPVDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIA
                     MLPILTGNVGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTA
                     IRDGVRGKDKLDVPIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTS
                     SAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWILSEVAKR
                     LGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYK
                     AFRDDPEANPLKTPSGKIEIYSSRLAEIARTWELEKDEVISPLPVYASTFEGWDSPER
                     STFPLQLFGFHYKSRTHSTYGNIDVLKAAYRQEVWINPIDAQKRGIANGDMVRVFNHR
                     GEVRLPAKVTPRILPGVSAMGQGAWHEANMSGDKIDHGGCVNTLTTLRPSPLAKGNPQ
                     HTNLVEIEKI"
     gene            9646..12069
                     /gene="ynfF"
                     /locus_tag="ACHY1N_001460"
     CDS             9646..12069
                     /gene="ynfF"
                     /locus_tag="ACHY1N_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416105.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenate/tellurate reductase subunit YnfF"
                     /protein_id="HFS4043793.1"
                     /translation="MKIHTTEALMKAEISRRSLMKTSALGSLALASSAFTLPFSQMVR
                     AAEAPVEEKAVWSSCTVNCGSRCLLRLHVKDDTVYWVESDTTGDDVYGNHQVRACLRG
                     RSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTISDNLRRILKDYGNEAVHV
                     LYGTGVDGGNITNSNVPYRLMNSCGGFLSRYGSYSTAQISAAMSYMFGANDGNSPDDI
                     ANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGREDEWLP
                     IRPGTDGALACAIAWVLITENMVDQPFLDKYCVGYDEKTLPANAPRNAHYKAYILGEG
                     PDGIAKTPEWAAKITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTSRAIAM
                     LSVLTGNVGINGGNSGVREGSWDLGVEWFPMLENPVKTQISVFTWTDAIDHGKEMTAT
                     RDGVRGKEKLDVPIKFLWCYASNTLINQHGDINHTHEVLQDDSKCEMIVGIDHFMTAS
                     AKYCDILLPDLMPTEQEDLISHESAGNMGYVILAQPATSAKFERKPIYWMLSEVAKRL
                     GPDVYQTFTEGRSQHEWIKYLHAKTKERNPEMPDYEEMKTTGIFKKKCPEEHYVAFRA
                     FREDPQANPLKTPSGKIEIYSERLAKIADTWELKKDEIIHPLPAYTPGFDGWDDPLRK
                     TYPLQLTGFHYKARTHSSYGNIDVLQQACPQEVWINPIDAQARGIRHGDTVRVFNNNG
                     EMLIAAKVTPRILPGVTAIGQGAWLKADMFGDRVDHGGSINILTSHRPSPLAKGNPSH
                     SNLVQIEKV"
     gene            12080..12697
                     /gene="ynfG"
                     /locus_tag="ACHY1N_001461"
     CDS             12080..12697
                     /gene="ynfG"
                     /locus_tag="ACHY1N_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMSO reductase like molybdoenzyme iron-sulfur
                     subunit YnfG"
                     /protein_id="HFS4043794.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCDDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNAEKGHMTKCDGCYSRVAEGKQPICVESCPLRALEFGPIEELRQ
                     KHGTLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPEEV"
     gene            12699..13553
                     /gene="ynfH"
                     /locus_tag="ACHY1N_001462"
     CDS             12699..13553
                     /gene="ynfH"
                     /locus_tag="ACHY1N_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenate reductase membrane anchor subunit YnfH"
                     /protein_id="HFS4043795.1"
                     /translation="MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIV
                     RGMFFLWLLMGIGFIASVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWL
                     VAVIGKMPQALGKLWLLVSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
                     GPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLACIHSSVQQASALVP
                     DYASLQVWRVVLLCAGLGCWVCPLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHM
                     TVGMAIAG"
     gene            13596..14210
                     /gene="dmsD"
                     /locus_tag="ACHY1N_001463"
     CDS             13596..14210
                     /gene="dmsD"
                     /locus_tag="ACHY1N_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HFS4043796.1"
                     /translation="MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWET
                     QWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
                     RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR"
     gene            14369..15661
                     /gene="clcB"
                     /locus_tag="ACHY1N_001464"
     CDS             14369..15661
                     /gene="clcB"
                     /locus_tag="ACHY1N_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0010447 - response to acidic pH [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /protein_id="HFS4043797.1"
                     /translation="MHHLHIYPDLRTMFRRLLIATVVGILAAFAVAGFRHAMLLLEWL
                     FLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQ
                     TDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWI
                     ACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDAL
                     LYNVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGG
                     LIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVF
                     TPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEM
                     TGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAQHS"
     gene            complement(15614..16309)
                     /gene="bioD"
                     /locus_tag="ACHY1N_001465"
     CDS             complement(15614..16309)
                     /gene="bioD"
                     /locus_tag="ACHY1N_001465"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="HFS4043798.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGS
                     KETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANL
                     TEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLA
                     MLRSVLAVDRVTV"
     gene            complement(16434..17654)
                     /gene="mlc"
                     /locus_tag="ACHY1N_001466"
                     /gene_synonym="dgsA"
     CDS             complement(16434..17654)
                     /gene="mlc"
                     /locus_tag="ACHY1N_001466"
                     /gene_synonym="dgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar metabolism global transcriptional
                     regulator Mlc"
                     /protein_id="HFS4043799.1"
                     /translation="MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALR
                     DLSSKLVVEESQELALKDDSPLLDRIISHIDQFFIRHQKKLERLTSIAITLLGIIDTE
                     NGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILE
                     LAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            complement(17789..18682)
                     /gene="ynfL"
                     /locus_tag="ACHY1N_001467"
     CDS             complement(17789..18682)
                     /gene="ynfL"
                     /locus_tag="ACHY1N_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4043800.1"
                     /translation="MNIELRHLRYFVAIAEELHFGRAAARLNISQPPLSQQIQALEQQ
                     IGARLLARTNRSVLLTAAGKQFLADSRQILSMVDDAAARAERLHQGEAGELRIGFTSS
                     APFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRNTALPETLEH
                     AVIVHEPLMAMIPHDHPLANNPNVTLAELAKEPFVFFDPHVGTGLYEDILGLMRRYHL
                     TPVITQEVGEAMTIIGLVSAGLGVSILPASFKRVQLNEMRWVPIAEEDAVSEMWLVWP
                     KHHEQSPAARNFRIHLLNALR"
     gene            18789..20042
                     /gene="ynfM"
                     /locus_tag="ACHY1N_001468"
     CDS             18789..20042
                     /gene="ynfM"
                     /locus_tag="ACHY1N_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4043801.1"
                     /translation="MSRTTTVDGAPASDTDKQSISQPNQFIKRGTPQFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAV
                     VGLLSLAYLTGTWSSPKAGTMTTRYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRAKRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNG
                     VGAFIALMLVIALLVGTRLHRRLHA"
     gene            complement(20091..20210)
                     /locus_tag="ACHY1N_001469"
     CDS             complement(20091..20210)
                     /locus_tag="ACHY1N_001469"
                     /inference="COORDINATES: protein motif:HMM:NF033695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KPN_01571 family protein"
                     /protein_id="HFS4043802.1"
                     /translation="MTHSKMNPFIWVLIILMTLDALRELAGASSILGWLLTLV"
     gene            20466..20774
                     /gene="asr"
                     /locus_tag="ACHY1N_001470"
     CDS             20466..20774
                     /gene="asr"
                     /locus_tag="ACHY1N_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310330.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance repetitive basic protein Asr"
                     /protein_id="HFS4043803.1"
                     /translation="MKKVLALVVAAAMGLSSAAFAAETANTPAPTATTTKAAPAKTTH
                     HKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAGKHSHQQPAKPAAQPAA
                     "
     gene            20867..20950
                     /locus_tag="ACHY1N_001471"
     CDS             20867..20950
                     /locus_tag="ACHY1N_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043804.1"
                     /translation="MVGRYRFEFILIILILCALIAARFYLS"
     gene            21050..21871
                     /gene="ydgD"
                     /locus_tag="ACHY1N_001472"
     CDS             21050..21871
                     /gene="ydgD"
                     /locus_tag="ACHY1N_001472"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HFS4043805.1"
                     /translation="MRTTIAVVLGAISLTSAFVFADKPDVAKSANDEVSTLFFGHDDR
                     VPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRF
                     VSNKGLWRYDIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITP
                     LPLFEGDKAALTAALKSAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDT
                     LPGDSGSPLMLHTDDGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK"
     gene            complement(21910..22239)
                     /gene="mdtI"
                     /locus_tag="ACHY1N_001473"
     CDS             complement(21910..22239)
                     /gene="mdtI"
                     /locus_tag="ACHY1N_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HFS4043806.1"
                     /translation="MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAG
                     MIMVKLA"
     gene            complement(22226..22591)
                     /gene="mdtJ"
                     /locus_tag="ACHY1N_001474"
     CDS             complement(22226..22591)
                     /gene="mdtJ"
                     /locus_tag="ACHY1N_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015606 - spermidine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015848 - spermidine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HFS4043807.1"
                     /translation="MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLS
                     YIFLSFAVKKIALGVAYALWEGIGILFITLFSVMLFDESLSLMKIAGLTTLVAGIVLI
                     KSGTRKARKPELEVNHGAV"
     gene            23003..23146
                     /locus_tag="ACHY1N_001475"
                     /pseudo
     CDS             23003..23146
                     /locus_tag="ACHY1N_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416118.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pheromone autoinducer 2 transporter"
     gene            complement(23657..23938)
                     /locus_tag="ACHY1N_001476"
     CDS             complement(23657..23938)
                     /locus_tag="ACHY1N_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043808.1"
                     /translation="MTEAEILRLIRRVSGISQQHDEQATQPDSVTAENYARVVAEVMR
                     RDGIQLNDVDMRNIRIRVLEMLAYRRRVQTYREKAKITYHWKKPERLRT"
     gene            complement(23952..25613)
                     /locus_tag="ACHY1N_001477"
     CDS             complement(23952..25613)
                     /locus_tag="ACHY1N_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HFS4043809.1"
                     /translation="MTAWNKYAEDVKTGKIPACKRLKQAVKRYFSDLENSLYMFDREV
                     VERFIVFSRVCPHVKGPMRGRPIELEPWQQFAFACILGFKVKATGRRKYTSAFIEVPR
                     KNAKSTTAAILANWFLIMENGQQDIYTAAVSRDQARIVFDDARQMCLLSRPLRKRVNI
                     QAHKVMHPKSNSLLKPLAAKAATIEGTNPSLAIVDEYHLHPDNGVYSALELGMGARPE
                     GLLFAITTSGSNVVSACKQHYDYCCQILDGEEVNDSIFVLIYELDDENEVDDPEMWIK
                     ANPNIDVSVDREKLASTIQKARGIPSQWVEMMTKRFNIWCQGATPWMGNGAWAECAGK
                     FTEEDLHGQECYAGLDLSSTSDISSVCYAFPVGKNIMLVSRHYLPEFQLQNPANKNRA
                     IYRQWARAGWIRTTPGDCIDYDRIRDDIMQDAEKFNIRLVGFDTWNATHLRTQLQGAG
                     FEVEPFPQTYLRFSPAAKSFEVFVNRRVIVHRGDPVLSWSMSNVVMQSDANANIKPNK
                     KKSPNKIDPSVAALMAFGTFQAEHEDFAFDISDSHRQKLEEFSGV"
     gene            complement(25597..25953)
                     /locus_tag="ACHY1N_001478"
     CDS             complement(25597..25953)
                     /locus_tag="ACHY1N_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFS4043810.1"
                     /translation="MARPPKAPAYLDDIAVKQWREKSRQLAERGDLTPADWSNLELYC
                     VNYSIYRKAVADLAARGFSIVNSQGGESRNPALSAKSDAERVMIKMASLLGFDPISRR
                     KNPPETEEEDELDRLE"
     gene            complement(26077..26259)
                     /locus_tag="ACHY1N_001479"
     CDS             complement(26077..26259)
                     /locus_tag="ACHY1N_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043811.1"
                     /translation="MALMNEREQNRLIRGLIRQRDAWKAQEAGHKDKASGRAERITAT
                     RLNDRDREVMECFRNR"
     gene            complement(26243..26683)
                     /locus_tag="ACHY1N_001480"
     CDS             complement(26243..26683)
                     /locus_tag="ACHY1N_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFS4043812.1"
                     /translation="MPWQPLRRCTEPGCNRRVKSGKCEEHRRSARQQQDSRRGSSRER
                     GYTRQWEKYRAMYLSKNPLCAHCLEKGIYTPAVVVDHIIPIDGGNDVLFWPEWNHQPL
                     CQACHNQKTKWLDPSTKNKRAAGGFREEEERGANRNNWMYGADE"
     gene            complement(26683..26976)
                     /locus_tag="ACHY1N_001481"
     CDS             complement(26683..26976)
                     /locus_tag="ACHY1N_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFS4043813.1"
                     /translation="MTELITLEEVKLHCRIDGDDEDQLISGYIAASLEACQIHIGRRF
                     DDGLEFTPAIKIGCMMFIAHLYENRQIVADNAKTHVPMTIGALWTAYRDVGVY"
     gene            complement(26973..27311)
                     /locus_tag="ACHY1N_001482"
     CDS             complement(26973..27311)
                     /locus_tag="ACHY1N_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFS4043814.1"
                     /translation="MNIGRLRDRVTIQTLKQTRAMTGEILETWVDGHTLWASVNMISS
                     KEAISSGAELATGTVRIWIRYRKDINATSRIKVNTGPLAGRVLNIIGQPLPDAARTRL
                     EILCSEGAEK"
     gene            complement(27308..28519)
                     /locus_tag="ACHY1N_001483"
     CDS             complement(27308..28519)
                     /locus_tag="ACHY1N_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4043815.1"
                     /translation="MWPFRRKKEQRSMTLDEFMALAGTSNTGAGEYVSSGTAESLPAV
                     MNAVTVISEAVATMPCYLYLVRNEKGKEAREWLDSHPVDHILNERPNAWQTPYQFKRM
                     MIRHCLLNGNAYAVIQWGRDGFPAALHPYPPQSVNVEQTGEHNWRYCITDAYTGNTRN
                     YLPWEVLHLRYSTDDGFMGRSPVTICRESLGLGLAQQRHGASVMRDGMMAAGVITSGE
                     WLDGVKGKQALAALERYKGARNAGKTPILEGGMSYQKLGMSNQDAEWLASRRFTIEDI
                     ARMFNVSPIFLQEYSNSTYSNFSEASRAFLTMTMRPWLANFEQQIKNALLVASPVPGI
                     RYQVEFDSADLLRATPGERFATYERGIKSGVMCPNEAREREGLSPRDGGDEFSQAWKQ
                     EVKISEGEKPE"
     gene            complement(28521..29078)
                     /locus_tag="ACHY1N_001484"
     CDS             complement(28521..29078)
                     /locus_tag="ACHY1N_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005115281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFS4043816.1"
                     /translation="MKSMEIRSSEITTSASNTLTGYVVRWDNLSELLWGEFYEKFQRG
                     AFTEWLAAGNDVRGLYEHDHSMLLGRTRSGTLKLEEDDTGLRFELTPPDTSTGRDVIE
                     LVKRGDISGMSFGFRSRKDVWDTTTDPCVRTVLVAELYEITVTSVPAYPDSGVELARR
                     SLYEQHPEKMPRADNRRWWADLAGV"
     gene            complement(29134..30291)
                     /locus_tag="ACHY1N_001485"
     CDS             complement(29134..30291)
                     /locus_tag="ACHY1N_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFS4043817.1"
                     /translation="MPRIIELRQQKTAIKNQMRDMLENAEKENRSLNDAEGAKFDELR
                     AKAESLDKDISRLEAIADEERSKPGKSSQTTDPAELRNYILTGETRALSTGVPADGGY
                     TVIPELNTEIMRMLADESTMRRICTVKKISSNEFKQLVSAGGATVNHGEEGKAREQTS
                     TPQINEVSIKLYPVYAYPRTTQEIVDFSDVDILSWLTGEIGDTFTETEESDLVVGDGD
                     KKAKGFLSVPRAEKNDKERDFGTLQVIKPSESLAWTSADPLIDLKFALRKKYRKNAVW
                     VVNSTTAAKLQKVKNANGDYIWRDRLQAGDPDTLLGLPVEYLEFMPDNVIALGDFKRG
                     YYIVDHETGVRTRPDNLTEPGFIKIFTQKYLGGGVVDSNAIKILELPQDDD"
     gene            complement(30583..30807)
                     /locus_tag="ACHY1N_001486"
     CDS             complement(30583..30807)
                     /locus_tag="ACHY1N_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309616.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043818.1"
                     /translation="MPMKFDEILKQRDKYHADNMETMNINDYRAFLETGALIEKDRHG
                     FVRCALSGEMLAVNPEQIDALIEFLKGIRD"
     gene            complement(30933..31205)
                     /locus_tag="ACHY1N_001487"
     CDS             complement(30933..31205)
                     /locus_tag="ACHY1N_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HFS4043819.1"
                     /translation="MVHDRIAEELEAKGFYRRAAARWGEVMMLVETDKERHHITMRRL
                     ECSRKAQRPPEPPDNFGDLRNAVNRTCAEMGIDGAGDEIRRNYQDS"
     gene            complement(31216..31626)
                     /locus_tag="ACHY1N_001488"
     CDS             complement(31216..31626)
                     /locus_tag="ACHY1N_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFS4043820.1"
                     /translation="MTAQIAAYGRLVDDPQVKQTSKGTPMTLARMAVSLPCSQAQDGQ
                     ATLWLSVLAFCKQADQLAGHEKGNVISVSGTMQISQWTGQNGETRQGYQVIADSVISA
                     KTVRPGGSRRKTTGTQGNQPPAGGDDPYGDDIPF"
     gene            complement(31636..31941)
                     /locus_tag="ACHY1N_001489"
     CDS             complement(31636..31941)
                     /locus_tag="ACHY1N_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001294167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043821.1"
                     /translation="MSEPKFGEKFYKHNGRITILQISAATPGWWVETDEGSSPVASWA
                     LCVLSYPDRDVYQDILPVISTDKGMKPVDIKNMGFQCVMLTEKMMEEMKKNNAGSLH"
     gene            complement(31938..32189)
                     /locus_tag="ACHY1N_001490"
     CDS             complement(31938..32189)
                     /locus_tag="ACHY1N_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043822.1"
                     /translation="MTKMRRDRTQQKYKALDMTELSLKVAIKVIDRHTREGYAKENPE
                     LISAFMTTAAANFATLTEREIAEAEQVTTINVKTGEVES"
     gene            complement(32537..34291)
                     /locus_tag="ACHY1N_001491"
     CDS             complement(32537..34291)
                     /locus_tag="ACHY1N_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707046.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5906 domain-containing protein"
                     /protein_id="HFS4043823.1"
                     /translation="MKLAPNVKQQSRGIKHKETEVIIFAGSDAWSHAKQWQEHDARMA
                     GDNEPPVWLGDQQLSELDKLQIVPEGRKSVRIFRAGHLEPVMIKAIGQKLAAAGVQDA
                     NFYPEGMHVQEVENWREYLARERQNLSEGLFVELPVKQKAQLSQMADSERAQLLSDRF
                     DGVCVHPESEIVHVWRGGLWCPVSTMELSREMVAIYSEHRATFSKRVINNAVEALKVI
                     AEPMGEPSGDLLPFANGALDLKTGEFSPHTPENWITTHNGIEYTPPAPGENIRDNAPN
                     FHKWLEHAAGKDPRKMMRICAALYMIMANRYDWQMFIEATGDGGSGKSTFTHIASLLA
                     GKQNTVSAEMTSLDDAGGRAQVVGSRLIVLADQPKYTGEGTGIKKITGGDPVEINPKY
                     EKRFTAVIRAVVLTTNNNPMIFTERAGGVARRRVIFRFDNIVSEAEKDKDLPEKVAAE
                     IPVIIRRLLANFADPEKARALLLEQRDGDEALAIKQQTDPVIEFCQFLNFLEEARGLM
                     MGGGGDSVKYTTRNSLYRVYLAFMAYAGRSKPLNVADFSKAMKPAAKVYGCEYITRRV
                     KGLTQTNVTTTEDCDAFL"
     gene            complement(34288..34587)
                     /locus_tag="ACHY1N_001492"
     CDS             complement(34288..34587)
                     /locus_tag="ACHY1N_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HFS4043824.1"
                     /translation="MKLKYPGLTASGKTRTKFMCGDIYRDKYGGTVMIKGVEERRVTY
                     RREGYEYDCVMPVYQFDRDFSLVQAVPRNVPTSREKARANIQEIRKMLNVFRGKK"
     gene            complement(34593..34826)
                     /locus_tag="ACHY1N_001493"
     CDS             complement(34593..34826)
                     /locus_tag="ACHY1N_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043825.1"
                     /translation="MRDIYHETIYRAFLALSHSENMLEILRIWHETLGDNECDKQKSR
                     IVTALITLLEPVIMELQEIDLLHDRYKEQHTGE"
     gene            complement(34828..35262)
                     /locus_tag="ACHY1N_001494"
     CDS             complement(34828..35262)
                     /locus_tag="ACHY1N_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043826.1"
                     /translation="MQNKTTPDAAAAALTTLMHALIDIECTAVLAQKEEREEYTLFAL
                     ECIRYTATRSMNDAKNILIADCENGGVMRDDRFNSLKHEFSGVSDDAGDALSSISKLI
                     RASFFLIGTKEYKSTGIDVLNIAADYADFVTEVILRKTTDGD"
     gene            complement(35463..35927)
                     /locus_tag="ACHY1N_001495"
                     /pseudo
     CDS             complement(35463..35927)
                     /locus_tag="ACHY1N_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitor Icd-like protein"
     gene            complement(35920..36117)
                     /locus_tag="ACHY1N_001496"
     CDS             complement(35920..36117)
                     /locus_tag="ACHY1N_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitor Icd-like protein"
                     /protein_id="HFS4043827.1"
                     /translation="MVAVNHIPHLVHTQTAFVWRFLALSAGESQIIHVTAWTEREARS
                     RCPSGCVAVFAARIRQGSHHA"
     gene            36307..36612
                     /locus_tag="ACHY1N_001497"
     CDS             36307..36612
                     /locus_tag="ACHY1N_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HFS4043828.1"
                     /translation="MATANKNAKSQLTTVRVPLDVMQGMESVKLDGESNAGFIVTAMR
                     GEIARRQAEGSGENPLVSSLDALAKVEQIGIKAAEDIGQLVTVAREELQRRKTQESE"
     gene            36737..37066
                     /locus_tag="ACHY1N_001498"
     CDS             36737..37066
                     /locus_tag="ACHY1N_001498"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043829.1"
                     /translation="MNQNDSRRVLLPLRSTLKNTHQRRELRSYGNALNQTDCIAHQPD
                     SGYHPRAYVWDHTHKLRSGLSVQKGGSISGPLFLCLKNSNFVVFQFHQGERIPAHIRA
                     YIQSSWL"
     gene            complement(37116..37304)
                     /locus_tag="ACHY1N_001499"
     CDS             complement(37116..37304)
                     /locus_tag="ACHY1N_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001443601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4043830.1"
                     /translation="MLSTDRFIREKECEKLTGLSRTCRYRMEKAGQFPSRRKLGGRSV
                     GWSLSEVLAWKDSCKAVH"
     gene            complement(37669..38898)
                     /locus_tag="ACHY1N_001500"
     CDS             complement(37669..38898)
                     /locus_tag="ACHY1N_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4043831.1"
                     /translation="MSRAMNKLSDTLLRKLHGKPAEKNTFYSDGGNLSVKYLTSGKLT
                     WYFTYRAGTGRETRPERIKLGSYPDLSLKAAREKAAQCRAWLAEGKNPRHEMNYTVQE
                     ALKPVTVGDALTYWLESYVKENRVDYIALKRRLNNHVIQHIGAMPLDKCELRHWLACF
                     DQVAKRTPVTAGFVLQACKQALKFCRRRRYAISNVLDDLNVADVGKKPDISERVLSTK
                     ELGELLQALDKKIFSPYYVALIRLLIVFGARTVELRLSEIGEWDFTEMLWTVPKEHSK
                     TKVAIFRPIPEAILPFVMKLVEQNRHTGLLLGEVKQEASVSQYGRLAHRRLKHPQWSL
                     HDIRRTFTTMLNDLGADPHVVEQLTGHQMPGMQRVYNHSRYLDAKRDALDMWTERLGI
                     LAGAHENVTTLPVARRK"
     gene            38886..39068
                     /locus_tag="ACHY1N_001501"
     CDS             38886..39068
                     /locus_tag="ACHY1N_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001332680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043832.1"
                     /translation="MLCSRFTPSLRKSDYTSDYTDRYTKGYNVKQAGTRKNTNLLIIK
                     NIMHNLKHYETAKNTK"
     gene            39075..39980
                     /gene="tqsA"
                     /locus_tag="ACHY1N_001502"
                     /pseudo
     CDS             39075..39980
                     /gene="tqsA"
                     /locus_tag="ACHY1N_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416118.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2 transporter TqsA"
     gene            complement(40005..41393)
                     /gene="pntB"
                     /locus_tag="ACHY1N_001503"
     CDS             complement(40005..41393)
                     /gene="pntB"
                     /locus_tag="ACHY1N_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008750 - proton-translocating NAD(P)+
                     transhydrogenase activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HFS4043833.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR
                     HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGD
                     AKASVDAILKAL"
     gene            complement(41404..42936)
                     /gene="pntA"
                     /locus_tag="ACHY1N_001504"
     CDS             complement(41404..42936)
                     /gene="pntA"
                     /locus_tag="ACHY1N_001504"
                     /EC_number="7.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008750 - proton-translocating NAD(P)+
                     transhydrogenase activity [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HFS4043834.1"
                     /translation="MRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLAS
                     FDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELM
                     QKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKTAPKLITREMVDSMK
                     AGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQAAQKAAPEVKTE
                     EKCACSPWRKYALMALAIILFGWLASVAPKEFLGHFTVFALACVVGYYVVWNVSHALH
                     TPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFR
                     KN"
     gene            43460..44404
                     /gene="ydgH"
                     /locus_tag="ACHY1N_001505"
     CDS             43460..44404
                     /gene="ydgH"
                     /locus_tag="ACHY1N_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 family protein YdgH"
                     /protein_id="HFS4043835.1"
                     /translation="MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTG
                     RFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGNSGNWRVVADLYKADAEKAEETSNR
                     VINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDA
                     NQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEAAKKVEIPGVATTA
                     SPSSEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTE
                     VSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK"
     gene            44590..45972
                     /gene="ydgI"
                     /locus_tag="ACHY1N_001506"
     CDS             44590..45972
                     /gene="ydgI"
                     /locus_tag="ACHY1N_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4043836.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWG
                     ITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASL
                     WLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIA
                     SVPATWMLVG"
     gene            46009..46731
                     /gene="folM"
                     /locus_tag="ACHY1N_001507"
     CDS             46009..46731
                     /gene="folM"
                     /locus_tag="ACHY1N_001507"
                     /EC_number="1.5.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydromonapterin reductase"
                     /protein_id="HFS4043837.1"
                     /translation="MGKAQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAI
                     DGLIKAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGTPLADVL
                     ACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHVAYAASKAALD
                     NMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVD
                     YLLTSCFVTGRSFPLDGGRHLR"
     gene            complement(46728..47063)
                     /gene="ydgC"
                     /locus_tag="ACHY1N_001508"
     CDS             complement(46728..47063)
                     /gene="ydgC"
                     /locus_tag="ACHY1N_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HFS4043838.1"
                     /translation="MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIEALRATIIFSMWSIIPYFVYLVSLWYFTGMMRLPAAFVGSVACWGISAWV
                     LIICWIKLH"
     gene            47192..47911
                     /gene="rstA"
                     /locus_tag="ACHY1N_001509"
     CDS             47192..47911
                     /gene="rstA"
                     /locus_tag="ACHY1N_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HFS4043839.1"
                     /translation="MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRE
                     SPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQNEQATLTKGLQETSLTPYKALHFGTLTIDPINRVVTLANTEI
                     SLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAA
                     EPYRIKTVRNKGYLFAPHAWE"
     gene            47915..49216
                     /gene="rstB"
                     /locus_tag="ACHY1N_001510"
     CDS             47915..49216
                     /gene="rstB"
                     /locus_tag="ACHY1N_001510"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HFS4043840.1"
                     /translation="MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMN
                     SSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVA
                     LDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALITFIAISLAFPVFIWMRPH
                     WQDMLKLEAAAQRFGDGHLNERIHFDEGSSFERLGIAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELH
                     LSEPDLPLWLSTHLADIQAVTPDKTVRIKTLAQGHYAALDMRLMERVLDNLLNNALRY
                     CHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLA
                     IVHSIALAMGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA"
     gene            49292..50221
                     /gene="tus"
                     /locus_tag="ACHY1N_001511"
     CDS             49292..50221
                     /gene="tus"
                     /locus_tag="ACHY1N_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006274 - DNA replication termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HFS4043841.1"
                     /translation="MARYDLVDRLNTTFRQMEQELAAFAAHLEQHKLLVARVFSLPEV
                     KKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLT
                     VLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQD
                     IAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGE
                     LLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD"
     gene            complement(50218..51621)
                     /gene="fumC"
                     /locus_tag="ACHY1N_001512"
     CDS             complement(50218..51621)
                     /gene="fumC"
                     /locus_tag="ACHY1N_001512"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045239 - tricarboxylic acid cycle
                     heteromeric enzyme complex [Evidence IEA];
                     GO_function: GO:0004333 - fumarate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006106 - fumarate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HFS4043842.1"
                     /translation="MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSL
                     IHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQS
                     NMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQL
                     IPQLKTLTQTLSEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYS
                     LPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALT
                     MLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIE
                     PNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEF
                     DSWVRPEQMVGSMKAGR"
     gene            complement(51764..53410)
                     /gene="fumB"
                     /locus_tag="ACHY1N_001513"
     CDS             complement(51764..53410)
                     /gene="fumB"
                     /locus_tag="ACHY1N_001513"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HFS4043843.1"
                     /translation="MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSVSEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGCDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKEL
                     LIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIW
                     IEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK"
     gene            53609..54784
                     /gene="manA"
                     /locus_tag="ACHY1N_001514"
     CDS             53609..54784
                     /gene="manA"
                     /locus_tag="ACHY1N_001514"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416130.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009298 - GDP-mannose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HFS4043844.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKS
                     SSRVQNAAGDIVSLRDVIESNKSTLLGEAVAKRFGELPFLFKVLCAAQPLSIQVHPNK
                     RNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALTPFLAMNAFREFSEIVSLLQP
                     VAGAHPAIAHFLQQPNAERLSELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIR
                     LISEFYPEDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEAKPANQLLTQPVKQGAELDFPIPVDDFAFSLHDLSDKETT
                     ISQQSAAILFCVEGDATLWKGSQQLQLKPGESAFIAANESPVTVKGHGRLARVYNKL"
     gene            54885..56393
                     /gene="ydgA"
                     /locus_tag="ACHY1N_001515"
     CDS             54885..56393
                     /gene="ydgA"
                     /locus_tag="ACHY1N_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HFS4043845.1"
                     /translation="MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQL
                     KLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKENPWIKSGQSVIFNESVDHGPFP
                     LAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLK
                     PLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLK
                     TDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLESMEINGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPEIANNPELY
                     QEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLA
                     QEVDRSVKSLDAKLTIPVDMATEFMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFR
                     LTTLQDNTITTSLQYTNGQITLNGQKMPLEDFVGMFAMLALNVPVVPAIPQQ"
     gene            complement(56438..57703)
                     /gene="uidC"
                     /locus_tag="ACHY1N_001516"
     CDS             complement(56438..57703)
                     /gene="uidC"
                     /locus_tag="ACHY1N_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416132.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide uptake porin UidC"
                     /protein_id="HFS4043846.1"
                     /translation="MRKIVAMAVICLTAASGLTSAYAAQLADDEAGLRIRLKNELRRA
                     DKPSAGAGRDIYAWVQGGLLDFNSGYYSNIIGVEGGAYYVYKLGARADMSTRWYLDGD
                     KSFGFALGAVKIKPSENSLLKLGRFGTDYSYGSLPYRIPLMAGSSQRTLPTVSEGALG
                     YWALTPNIDLWGMWRSRVFLWTDSTTGIRDEGVYNSQTGKYDKHRARSFLAASWHDDT
                     SRYSLGASVQKDVSNQIQSILEKSIPLDPNYTLKGELLGFYAQLEGLSRNTSQPNETA
                     LVSGQLTWNAPWGSVFGSGGYLRHAMNGAVVDTDIGYPFSLSLDRNREGMQSWQLGVN
                     YRLTPQFTLIFAPIVTRGYESSKRDVRIEGAGILGGMNYRVSEGPLQGMNFFLAADKG
                     REKRDGSTLGDRLNYWDVKMSIQYDFMLK"
     gene            complement(57742..59115)
                     /gene="uidB"
                     /locus_tag="ACHY1N_001517"
     CDS             complement(57742..59115)
                     /gene="uidB"
                     /locus_tag="ACHY1N_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide transporter"
                     /protein_id="HFS4043847.1"
                     /translation="MNQQLSWRTIVGYSLGDVANNFAFAMGALFLLSYYTDVAGVGAA
                     AAGTMLLLVRVFDAFADVFAGRVVDSVNTRWGKFRPFLLFGTAPLMIFSVLVFWVPTD
                     WSHSSKVVYAYLTYMGLGLCYSLVNIPYGSFATAMTQQPQSRARLGAARGIAASLTFV
                     CLAFLIGPSIKNSSPEEMVSVYHFWTIVLAIAGMVLYFICFKSTRENVVRIVAQPSLK
                     ISLQTLKRNRPLFMLCIGALCVLISTFAVSASSLFYVRYVLNDTGLFTVLVLVQNLVG
                     TVASAPLVPGMVARIGKKNTFLIGALLGTCGYLLFFWVSVWSLPVALVALAIASIGQG
                     VTMTVMWALEADTVEYGEYLTGVRIEGLTYSLFSFTRKCGQAIGGSIPAFILGLSGYI
                     ANQVQTPEVIMGIRTSIALVPCGFMLLAFVIIWFYPLTDKKFKEIVVEIDNRKKVQQQ
                     LISDITN"
     gene            complement(59112..60923)
                     /gene="uidA"
                     /locus_tag="ACHY1N_001518"
     CDS             complement(59112..60923)
                     /gene="uidA"
                     /locus_tag="ACHY1N_001518"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HFS4043848.1"
                     /translation="MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRA
                     IAVPGSFNDQFADADIRNYVGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQ
                     EVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSY
                     FHDFFNYAGIHRSVMVYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRD
                     ADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAV
                     KGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYA
                     EEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAI
                     KELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCD
                     AHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVD
                     TLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGN
                     KKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ"
     gene            complement(61311..61901)
                     /gene="uidR"
                     /locus_tag="ACHY1N_001519"
     CDS             complement(61311..61901)
                     /gene="uidR"
                     /locus_tag="ACHY1N_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator UidR"
                     /protein_id="HFS4043849.1"
                     /translation="MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAIS
                     PGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQR
                     ALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTSMTSRLLL
                     DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS"
     gene            complement(62130..62897)
                     /gene="hdhA"
                     /locus_tag="ACHY1N_001520"
     CDS             complement(62130..62897)
                     /gene="hdhA"
                     /locus_tag="ACHY1N_001520"
                     /EC_number="1.1.1.159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HFS4043850.1"
                     /translation="MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN
                     ADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAVSKLGKVDILVNNAGGGGPK
                     PFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYA
                     SSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRL
                     GQPQDIANAALFLCSPAASWVSGQILTVSGGGVQELN"
     gene            complement(63009..64037)
                     /gene="malI"
                     /locus_tag="ACHY1N_001521"
     CDS             complement(63009..64037)
                     /gene="malI"
                     /locus_tag="ACHY1N_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mal regulon transcriptional regulator MalI"
                     /protein_id="HFS4043851.1"
                     /translation="MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAA
                     IEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHG
                     GKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRMAEEKAIPVIFASRASYLDDVD
                     TVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSD
                     WVLECTSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDR
                     YFEQQVSLAAFTDATPTTLDDIPVTWASTPARELGTTLADRMMQKITHEETHSRNLII
                     PARLIAAK"
     gene            64212..65804
                     /gene="malX"
                     /locus_tag="ACHY1N_001522"
     CDS             64212..65804
                     /gene="malX"
                     /locus_tag="ACHY1N_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IICB"
                     /protein_id="HFS4043852.1"
                     /translation="MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSS
                     HDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGF
                     VGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
                     LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINS
                     AGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSC
                     PTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVV
                     GGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHG
                     LSTKWYMVPVVAAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGY
                     NVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQV
                     VIGPQVQSVKDEMAGLMHTVQA"
     gene            65814..66986
                     /gene="malY"
                     /locus_tag="ACHY1N_001523"
     CDS             65814..66986
                     /gene="malY"
                     /locus_tag="ACHY1N_001523"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional maltose regulon transcriptional
                     repressor/cystathionine beta-lyase MalY"
                     /protein_id="HFS4043853.1"
                     /translation="MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAP
                     CIIEALNQRLMHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDTQTVVYGPSVIYMVSE
                     LIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADDWFCDMGKLEAVLAK
                     PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWS
                     NVARGDWALLTSGSKSFNIPALTGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTA
                     HIAAYQQGAPWLDALRVYLKDNLTYISDKMNAAFPELNWQIPQSTYLAWLDLRPLNID
                     DNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVR"
     gene            67090..68091
                     /gene="add"
                     /locus_tag="ACHY1N_001524"
     CDS             67090..68091
                     /gene="add"
                     /locus_tag="ACHY1N_001524"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004000 - adenosine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009168 - purine ribonucleoside
                     monophosphate biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFS4043854.1"
                     /translation="MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLI
                     PHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARHGLHYVELRFSPG
                     YMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
                     DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER
                     IGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASIN
                     TDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK"
     gene            complement(68126..69166)
                     /gene="ydgJ"
                     /locus_tag="ACHY1N_001525"
     CDS             complement(68126..69166)
                     /gene="ydgJ"
                     /locus_tag="ACHY1N_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFS4043855.1"
                     /translation="MSDNIRVGLIGYGYAIKTFHAPLIAGTPGLELAVISSSDETKVK
                     ADWPTVTVVSEPKHLFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLS
                     QARELDALAKSLGRVLSVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVR
                     DRWREQGGPGSGIWYDLAPHLLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSY
                     PQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRD
                     GVLTRVEGEERVEETLLTVPGNYPAYYAAIRDALNGDGENPVPASQAIQVMELIELGI
                     ESAKHRATLCLA"
     gene            69409..69534
                     /gene="blr"
                     /locus_tag="ACHY1N_001526"
     CDS             69409..69534
                     /gene="blr"
                     /locus_tag="ACHY1N_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HFS4043856.1"
                     /translation="MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK"
     gene            69807..70022
                     /gene="ydgT"
                     /locus_tag="ACHY1N_001527"
     CDS             69807..70022
                     /gene="ydgT"
                     /locus_tag="ACHY1N_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HFS4043857.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAAD
                     HRRAELVSGGRLFDLGQVPKSVWHYVQ"
     gene            70108..70548
                     /gene="ydgK"
                     /locus_tag="ACHY1N_001528"
     CDS             70108..70548
                     /gene="ydgK"
                     /locus_tag="ACHY1N_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707526.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HFS4043858.1"
                     /translation="MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTF
                     QTLGGQALTTQILWGVSFITAIAMWYYTLWLTIAFFKRRRCVPKHYIIWLLISVLLAV
                     KAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP"
     gene            70625..71206
                     /gene="rsxA"
                     /locus_tag="ACHY1N_001529"
     CDS             70625..71206
                     /gene="rsxA"
                     /locus_tag="ACHY1N_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HFS4043859.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRL
                     LGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            71206..71784
                     /gene="rsxB"
                     /locus_tag="ACHY1N_001530"
     CDS             71206..71784
                     /gene="rsxB"
                     /locus_tag="ACHY1N_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HFS4043860.1"
                     /translation="MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEIL
                     PQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQE
                     LTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CISLQPVAETPDSWKWDLNTIPVRIIPVEHHA"
     gene            71777..>73556
                     /gene="rsxC"
                     /locus_tag="ACHY1N_001531"
     CDS             71777..>73556
                     /gene="rsxC"
                     /locus_tag="ACHY1N_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HFS4043861.1"
                     /translation="MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFV
                     IPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSA
                     LAELSVIIDADGEDCWIPRDGWADYRTRSREELIERIHQFGVAGLGGAGFPTGVKLQG
                     GGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKP
                     QAISMLRAVLADSNDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLL
                     PQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEE
                     KRAAEAKARFEARQARLEREKAARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQAT
                     QPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARA
                     KARKLEQQQANAEPEEQVDPRKAAVEA"
BASE COUNT        17854 a        19061 c        17767 g        18874 t
ORIGIN      
        1 cgcacaatcg ttgagctggg gaaagccata gacttcgatg ccagaacggc tattccattc
       61 gaaggtgagc gccataatgc acttgatgac gcccgttacc aggcaaaata cgtttcagtt
      121 atctggcaaa aactgatccc gagtcaggct gattcttaat gttcaactgt cgccggttgt
      181 gactggtatt ctgcaaccgg cgctcgtctg atgtaagaga taaagaaagc gatgagcgaa
      241 gtaatcatga tcgtctctcc cggcaaatgg gtatccgaag agcagttaat tgcgctgaaa
      301 ggaataaaaa aaggtacgtt aaaaaaggcc cgggaaaaat cgtttatgga aggaagggaa
      361 tataagcatg tcgctcatga cggtatgcca tgggataaca gtccatgctt ttacaacctg
      421 gaagaaattg atcgctggat tgagcgccag gcatctgcaa gaccaagacg tcatcttgct
      481 tgactaaaag caacacgaac caatgagaga agctgaaatg aaatatccga caggcgtgga
      541 aaaccatgga gggaaattac gtatctggtt tgtttataaa ggtgtaagag tccgggaaaa
      601 tcttggggtt cctgacacag caaaaaacag gcgcattgca ggtgagctac gcgcctctgt
      661 ttgttacgca ataaaaactg gcgctttcga ctatgcaaaa cagtttcccg cctcacacaa
      721 tctggaaaaa tttggtgagg cccgacaaga tttaaccata aaagaactgg ctgaaaaatt
      781 tctggcactg aaagaaactg aagtcgcaaa aacgtcactc aacacgtacc gtgccgtcat
      841 caaaaatatt ctgagcataa tcggtgaaaa aaatcttgca tcatcgatta ataaagaaaa
      901 attgctggcg gtacgtaaag agttactgac tggataccag atccccaaaa gtaactatat
      961 tgttacacaa ccagggagat cggctgttac cgtaaataat tacatgacaa atctttacgc
     1021 cgtgttccag tttggtgttg ataacggtta tctggcagac aatccattta aggggatctc
     1081 accattaaag gagtcgagaa ccatcccgga tccactttcg cgggaggagt ttatccgcct
     1141 tattgacgcg tgcagaaatc agcaagccaa aaatttatgg tgtgtttccg tttatactgg
     1201 gattcgccct ggtgaactct gtgcgcttgg atgggaagat atagatctga aaaatggaac
     1261 aatgataatc agaagaaatc tggcaaaaga ccgttttaca gtaccaaaaa cacaggcggg
     1321 aaccaatcgt gtgattcacc ttattaagcc cgcaatcgac gctctccgga gtcagatggc
     1381 actaacgaga ctgagcaaag agcatatcat cgatgttcac ctcagagaat tcggcagaac
     1441 agagaaacaa aaatgtacct ttgtttttca acctgaagtg tcagcgaaag taaaaaatta
     1501 tggtgaccat tttaccgttg actcaataag gcagatgtgg gacgcagcgg taaagcgtgc
     1561 cggaatccgc catcgcaaat cgtatcagtc gagacacact tatgcctgct ggtcgttaac
     1621 agcaggagct aacccggcat tcattgcaaa ccagatgggc catgcagatg cgcaaatggt
     1681 gtttcaggtg tacgggaaat ggatgtcaga aaataataat gcgcaggtaa cgctgttaaa
     1741 tacacagtta agcgagtttg ccccaaccat gccccataac gaagcgatga aaagttaatt
     1801 ttttatttat caattagtta gattgaatga ctcttgaaat ccataaattc aagcgcagtg
     1861 cccagccatc ccgatactgc tgctttcacc aaatccttag tgcttctttc gtgtttttct
     1921 attgtcataa tggttatctc taaaaaagag gtaagatgcg tactacttac tcgccgttat
     1981 tggtattatt cagaaaaagt gagtaagact ttgcagcaat gtttttgatc ctgttcaaat
     2041 aaactaatgg catcagcaac atgctggaaa tcaaacgtat gggtaattaa tttttctggt
     2101 ttaattaacc ctttacttaa ccagtcgata acgaccggga atttatttgc atttaagcgt
     2161 gaagaaaaaa tagagagttc ttttccggta attccttgct gaatcacttc agacggttca
     2221 ctggagaagc ccatcaatac aatacgtgcc gctggagaag ccagcgttac ggcctctttc
     2281 aggatagaag gatgacaagc cgcatcgata attaatgtcg gcttgatgcc tttttcagtg
     2341 aaaatctcgc caagcggtgt ctggctgtta ttaatcgccc agtcagcccc gctctctttc
     2401 gctttttcca gtcgttcatc aatgcgatcg gcaacaatca catttttaac gttatagacg
     2461 ccttttaata cctgaacgat cgtcaggccg attggaccgg caccataaac cagaacggta
     2521 tcattttcag tcggttgacc atgtccggtt acgttagccg caatggtaaa aggttcgatc
     2581 attaccgcat attgatcggc cactgcttca ggaattttcc acgcattttt tgccggaacc
     2641 acggcatatt cactgaaacc accgtcagcg tgcacaccta atacagccag tgtcgtacaa
     2701 acgttcggtt tacctataga gcacggatag caatgcccac agctgaccac cggatcgaca
     2761 gcaacacgtt caccgactct ggcgctttcc acgccttcac ccactgcatc aatgacgcca
     2821 aagaattcat gaccaatgac gcgcggatat ttcgcaaaag gattatgccc acgataaata
     2881 tggctatctg aaccacaaat tccggcaagt ttcactttta ctcgcacttc acccgctgac
     2941 ggggtgggta tttcacgttc gacaatcgcc agttgattcg gtttttcaat taatatgctt
     3001 ttcattatct tactccttac cagttccaca gcgtgccatc ttccagacgt gcgactggta
     3061 gataagcagg ttcataggga tatttcgccg ccagcttttc atcgaattcg ataccaagac
     3121 ccggtttgtc tcccggatgc atatagccgt tatcgaaagt ccagttgtgc gggaagactt
     3181 cgagcatttg ttcggaataa cccatgtatt cctggacacc gaaattgggg acccacagat
     3241 caaagtgcag cgccgcagcc atgcagactg gtgacaaatc ggaaggaccg tgtgagccag
     3301 tacgtacctg atacagcgaa gcaaaatcgg caatccggcg cataccggta attccgcctg
     3361 catgggtcag cgtggtgcgg atataatcga tgagttgctc ttcaatcagt tgtttgcagt
     3421 cccagatgct gttgaagact tcacccactg cgatgggtgt gacggtatgt tggcgaatga
     3481 gacggaagca ttcctggttt tccgcaggtg tcgggtcttc catccagaac atgcgataat
     3541 cttcaatgct tttaccaaag cgcgccgctt caataggcgt taagcgatgg tgcatgtcat
     3601 gcagcaaatg ttcattaaaa ccaaacttgt tacgtaccgc gtcaaacaat ttcggcatga
     3661 aatcgaggta tttctccgtc gaccacagct gctcttccgg ccactgtcct ttggttgcgg
     3721 gttcataagc cagaccttta cctttcgaca tgccgtaggt ggttttcata ccagggattc
     3781 cgcactgcac gcggatggct ttgaatccca gctcctgatg acgggcataa tcatccagag
     3841 cttcatcaat actgtgaccg gtggtatggc aataaaccat caccccttca cgagacgcgc
     3901 cgccgagtaa ctggtaaagc ggcatgttgg ccgctttggc tttaatatcc cacagcgcca
     3961 tatcaaccgc tgaaatggcc gacatcgtaa ccggaccgcg acgccagtaa gcacctttat
     4021 agaaaaactg ccagatatct tcgatacggt gcgcatcgcg accaataagc tgcggacaaa
     4081 ggtgatcctg caaataagag gccacggaaa gctcacgtcc attgagagtg gcatccccaa
     4141 ggcccgtaat accgtcctca gtggtgattt ttaatgtgac gaaattacgc cccggacagg
     4201 taacaaaaac ttcagccttt acgatcttca tgttcgattc cttgcatcgc ttgtcgtgat
     4261 gcatgaaatc tacgcaactg agctactacc atacaagtat gaggatcgaa aaaagccgga
     4321 gtgatcacaa aaaaaggcgt atatttgcgc tgtgaatggt tgacaaaaga tgaaatagaa
     4381 taccttttgt cagctgacac ttcctcgtat cttattgata aaatggattt atgttcctac
     4441 gtgcgccccc agcccgcaac aatgatcaac atgccgcaaa gcgcaatcaa cgcacccgtc
     4501 cagtcataaa gagtcagttt cacgccatcc acaacgcgca gccacatcaa cgccgtgcag
     4561 acataaacgc caccataagc cgcgtaaaca cgcccactcg ccgcaggatg caacgttaac
     4621 aaccagacaa acagcgccag tgaaatcccc gccggaagca acagccagat actggcgttt
     4681 cgttttaacc acaaccaggg cagaaagcat ccaataattt cacacagcgc agtagcaaaa
     4741 aatagtaacg ttgttttaat catctttgtc acttattgac atcatgtata gttatagggc
     4801 cacataatat caccaatata aacaccctcc tgatacgttt tgcgttcgca gtggatggtg
     4861 tagaatcacc tttaatcatt catacaggga atgaattatg aaaatcactc tcagcaaacg
     4921 aatcggcctg ctcgcttttc tgctaccttg cgcactggca ttgagcacaa ctgttcatgc
     4981 cgaaactaac aaactggtga ttgagtctgg cgacagtgca caaagccgcc agcacgccgc
     5041 tatggaaaaa gagcaatgga atgacacgcg caatctgcgc cagaaagtga ataaacgcac
     5101 tgaaaaagag tgggataaag ccgacgccgc ttttgataac cgcgataaat gtgagcaaag
     5161 cgccaacatc aatgcctact gggagccaaa tactttgcgc tgcctggacc gtcgaactgg
     5221 ccgcgttatt accccctaac ctgttattga tttaaggaat gtaaggacac gttatgccaa
     5281 gcgcccacag tgttaagcta cgcccgctgg agcgtgaaga tttacgctat gtacatcaac
     5341 tcgacaataa cgccagtgtg atgcgttact ggtttgagga accctacgaa gcctttgttg
     5401 aactctctga tctgtatgat aagcatattc acgatcagag cgaacggcgc tttgtggtgg
     5461 aatgtgacgg cgaaaaagcc ggtctggtgg agctggtgga aattaaccat gttcatcgcc
     5521 gcgcagaatt tcagataatt atctccccgg agtatcaggg gaaaggtctg gcaacccgtg
     5581 ccgcaaaatt agcaatggac tatggcttta ccgttctcaa tctctataag ctgtatctga
     5641 tcgttgataa agagaatgaa aaagcgattc atatttaccg caagcttggc ttttcggttg
     5701 aaggtgaatt gatgcacgag ttctttatta atggtcaata tcgtaatgcc attcgcatgt
     5761 gtatattcca gcatcagtat ctggcagagc acaaaacacc gggtcagact ctcctgaagc
     5821 cgaccgcaca atagcattaa taataatcga tcgtattttt gatggtgtaa acccgttcga
     5881 cggcggggtt tactccttca tcaacaatga tcagctgaca gtccaccgga ttggcgtgac
     5941 tgtcatattc acagctctgt tttacattac caactcgttg attattcagt aaagtaactg
     6001 ctgtataatc taattttttg atcgggtccg ttgatggcgt ggcgctgaca gataatgttt
     6061 tgtcgttact tttcgtggtt ttacccagcg gatacccctg atcatcatag cgatattcca
     6121 tctgcatttg tttgctgctg gctttaatca cgaagccatt atcatcggtt tcccaactca
     6181 ccccggcaga aggtaattct gctagctggc attttccctg taaacgtact cttttctcca
     6241 gcgtctcagc atcacggtaa taattggcgt ccagtaccag agcgaccacg gtattatttt
     6301 ccagatccag taattcgagt gaatcaaaac agccttcttc cgacaaagtc ccagaaacac
     6361 gtttcgtcac ttcaccttgc tcatccatta atgtctgagt gaaatctttt accggaccac
     6421 gcagcggatc aaaatcgaat tcattagaga aactggccat ctcaggggta aatgaaagtg
     6481 ttacctctgt gcggtcacat cctgtgagga atatcgcgag taagcatggt agtaatttgt
     6541 atttcacaac agtcaccaga gagtagagat gattctcaat catagtagca aatacagtac
     6601 tttacacgtt aaatgctatg cttaaagaag ttatcttcgc gtaaggagct tatgatgaaa
     6661 ctctcaacct gctgtgccgc gcttctgctc gccctcgcct cacccgcggt actcgccgcg
     6721 ccgggatcct gtgagcgcat acagagcgat atatcacagc gcattatcaa taatggcgta
     6781 cccgaaagca gcttcacgtt aagtattgta cccaatgacc aggttgatca gcctgattcc
     6841 caggtcgtcg ggcattgtgc taatgatacg cataaaattc tctacacccg caccaccagc
     6901 ggtaacgtct ctgctcccgc gcagtctacc caggatggcg cgcctgccga accgcagtaa
     6961 cacattatcg actgaacgcc ggatacgaca catccggcga tttgaacata caacataatc
     7021 ccaccttatt actcataccc ttctattgat atggattaat aattcttaac ccaaaatggg
     7081 tagactccct ctattgttag cgcgctaaat attcaatata taaactttta tataacgata
     7141 aagaacaggg agtgagttat gtccaaaaat gaacgaatgg tgggcatcag ccgcagaaca
     7201 ctcgttaaat ctaccgcgat aggttctctg gcgctggctg caggcggttt ttctttgccg
     7261 tttaccctgc gcagtgcagc agcagcggta caacaggccc gcgaaaaagt ggtctggggt
     7321 gcctgttccg tcaactgtgg tagccgctgt gcacttcgtc tacatgttaa agataatgaa
     7381 gtgacctggg tggaaactga caataccggc agcgatgagt acggcaacca tcaggtacgc
     7441 gcctgtttgc gcggtcgctc catccgtcgg cgtattaatc atcccgatcg cttgaattat
     7501 ccaatgaaac gcgtgggcaa acgcggcgaa ggcaaattcg aacggattag ctgggatgaa
     7561 gccctggata ctatcgccag tagcctgaaa aaaaccgtcg aacaatatgg caatgaggct
     7621 gtatatattc agtactcttc ggggattgtt ggcggcaata tgacccgctc ttcgccatca
     7681 gcctcggcgg tcaaacgcct gatgaactgc tacggcggtt cactcaatca gtatggctcc
     7741 tacagcaccg cgcaaatttc ctgtgccatg ccctacacct acggcagtaa tgatggcaac
     7801 agcaccacgg atattgaaaa cagcaagctg gtcgtgatgt ttggtaacaa cccggcagaa
     7861 acccgcatga gcggcggtgg catcacttat cttcttgaaa aagcgcgcga gaaatcgaac
     7921 gccaaaatga ttgttatcga tccgcgatat accgatacgg ctgctggtcg tgaagatgaa
     7981 tggcttccta ttcgcccggg caccgatgcc gcgctggttg cgggtattgc ctgggtattg
     8041 attaacgaaa atctcgttga tcaacctttt ctcgataaat actgcgtcgg ctatgacgaa
     8101 aaaaccttac ccgcagatgc accaaaaaat ggtcactata aagcctatat tcttggtgaa
     8161 ggtgatgata acacagcgaa aacgccgcag tgggcttcgc aaattaccgg tatcccggtg
     8221 gaccgtatca tcaaactggc gcgtgaaatt ggcacagcaa aacccgctta tatctgccag
     8281 ggctgggggc cgcaacgcca ggcaaacggc gagctgactg cacgcgctat tgctatgttg
     8341 cctattttga cgggcaatgt cggcatcagc ggcggaaata gtggcgcgcg agaatcgacc
     8401 tataccatta ccatagaacg cctgccggtg ctggataatc cggtcaaaac gtcaatctcc
     8461 tgcttcagct ggacggatgc tatcgatcat ggtccgcaaa tgacggcaat ccgcgacggc
     8521 gtccgcggca aagataaact ggatgtgccc attaagttca tctggaacta cgcgggaaat
     8581 accctggtta atcagcattc tgacatcaac aaaacgcatg aaattctgca agacgaatcg
     8641 aaatgcgaaa tgattgtggt catcgaaaac tttatgacct catcggcaaa atatgccgac
     8701 attctgctgc cagacctgat gaccgttgag caggaagata ttattcctaa cgactacgcc
     8761 ggtaacatgg gatatctcat tttcctccag ccagtcacca gcgaaaaatt cgaacgtaaa
     8821 ccgatttact ggatcctgag tgaagtcgcg aaacgtcttg gacctgacgt ctatcaaaag
     8881 ttcacagaag gtcgcacgca ggaacaatgg ttacaacatc tgtacgccaa aatgcttgcc
     8941 aaagatccag cgttaccgtc ttacgacgaa ctgaaaaaaa tgggtatcta taagcgtaaa
     9001 gatcccaatg gtcattttgt cgcctacaaa gcatttcgtg acgaccccga ggcaaatcca
     9061 cttaaaacgc cttccggtaa gattgaaatt tattccagca ggctggcgga aattgcccgt
     9121 acctgggaac tggaaaaaga tgaagtgata agcccattgc cagtttatgc ctcaaccttt
     9181 gaaggctggg actcccctga acgtagtacc ttcccactgc aactgtttgg tttccattac
     9241 aaatcccgta ctcactcgac ctacggcaac attgatgtcc tgaaggctgc ctaccgtcag
     9301 gaggtgtgga tcaaccctat agatgcgcag aaacgtggga ttgccaacgg cgatatggtg
     9361 cgggtgttta accatcgtgg cgaagttcgg ctaccagcca aagtgacacc acgcattctc
     9421 cctggggtta gcgctatggg ccagggagcc tggcacgagg ccaatatgtc tggcgataaa
     9481 atcgaccatg gcggctgtgt gaatacgcta accactctgc gcccttcacc actggcgaag
     9541 ggaaacccgc agcacactaa tctggtcgag atcgaaaaaa tataacccac tacaaccata
     9601 aattctggca tgacattttg tttgaaaagc aataagtgag taatgatgaa aatccatacc
     9661 acagaggcgc tcatgaaggc tgaaatcagc cgtagaagtc tgatgaaaac ctccgcactt
     9721 ggcagtcttg cgctggcaag cagtgctttc actctgccat tttcccaaat ggtccgggcg
     9781 gcagaggctc cggtagaaga gaaagcggtc tggagttcct gcaccgttaa ctgcgggagc
     9841 cgctgtctgt tacgtttgca tgtgaaagat gacaccgtgt actgggtgga gtctgatacg
     9901 acaggtgacg acgtctacgg taatcatcag gttcgcgcgt gtttacgcgg gcgctctatc
     9961 cgccgacgga tgaatcatcc tgataggttg aaatatccca tgaagcgcgt cggcaagcgc
    10021 ggtgaaggta aatttgaacg gataagttgg gacgaagccc tggataccat cagtgataat
    10081 cttcggcgga tcctaaaaga ttacggcaat gaggctgtac atgtcctgta cggaacaggc
    10141 gtagatggcg gaaacatcac caactcaaac gtcccgtacc gtctgatgaa ctcttgcggt
    10201 ggttttctca gtcgctatgg cagctacagt accgcacaga tcagtgccgc aatgagttat
    10261 atgttcggtg ccaatgatgg caacagcccg gatgatatcg ccaatacgaa actggtcgtt
    10321 atgttcggaa ataacccggc agaaacgcgg atgagcggcg gtggtgtcac ttactacgtc
    10381 gagcaagccc gcgaacgttc aaacgcacgc atgatcgtca tcgatccacg ttataacgac
    10441 acagctgccg ggcgtgaaga tgaatggctg cccattcgcc caggcaccga tggcgcactg
    10501 gcctgtgcga ttgcctgggt actgattact gaaaacatgg tcgatcagcc atttctcgac
    10561 aaatattgtg ttggttacga tgaaaaaacg ctgcccgcca acgcaccacg taacgcgcat
    10621 tataaagcct atattctggg cgaagggcct gacggcatag ctaaaacgcc ggaatgggca
    10681 gcaaaaatca ccagcatccc ggcagaaaaa attatccagt tggcacgaga gatcggttca
    10741 gcaaaacctg cttatatttg tcagggttgg gggccacaac gacattccaa cggcgagcaa
    10801 acgtcccgcg ctattgccat gctttccgtt ctcaccggta acgtcggcat aaacggcggc
    10861 aactcaggtg tacgcgaagg tagctgggat ctgggggtag aatggttccc gatgcttgag
    10921 aaccctgtta aaacgcagat ttccgtcttt acatggacag atgccatcga ccatggtaag
    10981 gaaatgaccg cgacccgtga tggtgttcgt ggaaaagaaa aactggatgt ccccatcaag
    11041 tttttatggt gctacgccag taacacattg atcaatcaac atggcgacat caatcacacc
    11101 catgaggtgc ttcaggatga cagcaagtgc gagatgattg ttggcattga ccacttcatg
    11161 acggcctcgg ctaagtattg cgatatcctg ttgcccgacc tgatgccaac agagcaagaa
    11221 gaccttatct ctcatgaatc tgcagggaat atgggctatg tgatcctcgc ccaacccgca
    11281 acctctgcaa aatttgaacg caaacccatc tactggatgc tgagtgaagt cgccaaacgc
    11341 ttaggaccag acgtttatca aacctttact gaaggtcgca gtcagcatga atggatcaaa
    11401 tatctccatg cgaaaacgaa ggaacgtaac cctgagatgc ccgactacga ggagatgaaa
    11461 acgaccggga tctttaagaa aaaatgcccg gaagaacact acgtcgcttt ccgcgcattc
    11521 cgtgaagatc cccaggcaaa cccgttgaaa acaccttcgg ggaaaatcga aatttattct
    11581 gaacgactgg cgaagattgc ggatacctgg gaattgaaaa aagatgaaat tattcatccc
    11641 cttccagctt atacgccagg ttttgatggc tgggacgatc ccctgcggaa aacctatcca
    11701 ctgcagttaa cgggcttcca ctacaaggcg cgtacccact ccagctacgg caatattgat
    11761 gtgttacagc aggcctgccc acaagaggtg tggatcaacc ccattgatgc tcaggctcgc
    11821 ggtatccgtc atggcgatac cgtgcgggta tttaacaata atggagaaat gctgattgcc
    11881 gcaaaagtga ctccgcgtat tctgcctggc gttaccgcca tcgggcaagg tgcgtggctt
    11941 aaagcggata tgtttggtga ccgggtcgat cacggcggca gtatcaatat tctgacctct
    12001 caccgccctt caccgctggc aaagggaaac ccgtcgcaca gcaatcttgt ccagatcgaa
    12061 aaggtttaaa gagtagccca tgaccacaca atatggattt tttatcgatt ccagccgctg
    12121 tactggctgt aaaacctgcg aactggcgtg caaagatttt aaagatcttg gcccggaagt
    12181 cagtttccgc cgtatttatg aatatgctgg cggcgactgg caggaagata atggcgtctg
    12241 gcaccagaac gtgttcgctt attatctctc catctcctgt aaccattgcg atgacccagc
    12301 atgtacaaaa gtctgcccca gcggcgcaat gcataagcgt gaagatggct ttgtggtggt
    12361 tgatgaagat gtttgtatcg gctgccgcta ctgccacatg gcttgtccgt acggcgcacc
    12421 acagtacaat gctgaaaaag ggcacatgac gaagtgcgat ggttgttatt cgcgcgtcgc
    12481 cgaggggaaa caacccatat gcgtcgaatc ctgcccgctg cgtgcacttg agttcggtcc
    12541 aattgaagag ctgcgccaga agcacggcac tctggctgcc gtcgcgccac tgccgcgcgc
    12601 gcatttcaca aaacccaata tcgttatcaa acctaacgcc aacagccgcc cgaccggcga
    12661 taccactggt tatctggcta atccggagga agtgtaaaat gggaaatgga tggcatgaat
    12721 ggccactggt tatctttacc gtattgggtc aatgcgtagt aggcgcgctg attgttagcg
    12781 gaattggctg gttcgccgcc aaaaatgacg cagaccgtca gcgtattgtc cgtggcatgt
    12841 ttttcctctg gctgttgatg ggcatcgggt ttattgcctc tgtcatgcac ctgggatcgc
    12901 cactgcgagc gtttaactcg ctgaatcgaa tcggagcttc tggtctgagt aacgagattg
    12961 ctgccggttc catatttttt gccgttggcg gactatggtg gctggtggcg gtcatcggta
    13021 aaatgccgca agcgttgggg aaactctggt tacttgtcag catggcgctc ggcgtcattt
    13081 tcgtctggat gatgacctgc gtgtatcaaa tcgacaccgt gccaacctgg cataacggtt
    13141 acactacgct ggctttcttc ctgacggtat tgttgagcgg tccaatactt gctgccgcaa
    13201 ttctgcgggc agctcgcgtt acatttaata ccacaccatt tgccatcatt agcgttctgg
    13261 cgctgatcgc ttgtgccggg gtgattgtgc tgcaaggttt gtctctggcg tgtattcact
    13321 catccgtaca acaagccagc gcactggtac cagattacgc ctccttacag gtctggcgtg
    13381 tggtattgtt atgcgcaggt ctaggatgct gggtttgtcc gctcattcgt cgccgtgaac
    13441 ctcacgttgc cggacttatt ctggggttaa tcctcattct tggcggtgag atgatcgggc
    13501 gtgtgctctt ttatggcctg cacatgacgg taggaatggc tattgcaggt taacaaattg
    13561 gtgcggggca acccgcacat ttcaggatgt taggaatgac ccatttttca cagcaagata
    13621 atttttctgt cgcggcgcgc gtgttgggcg cgctgtttta ttacgctcca gagagtgcgg
    13681 aagccgcacc tctggttgcg gtactcacca gtgacggctg ggaaactcag tggcctctac
    13741 cagaagcgtc attagcgccg ctggtgacgg cttttcagac acagtgtgaa gagactcacg
    13801 cccaggcctg gcagcgtttg tttgtcggcc cgtgggcact gccgtctccg ccgtgggggt
    13861 cggtctggct ggatcgcgaa tctgtgctgt ttggcgattc aacattggca cttcgtcagt
    13921 ggatgcgcga gaaaggcatt cagtttgaaa tgaagcaaaa cgaaccggaa gatcattttg
    13981 gttcactgct gttgatggct gcgtggttgg cggagaatgg tcgccagaca gaatgcgaag
    14041 aattgctggc atggcacctt tttccgtggt caacacgttt tcttgatgtt tttatcgaaa
    14101 aagcagaaca ccctttctac cgtgcactgg gtgaactggc tcgcttaacg ctggcgcaat
    14161 ggcaatcaca actgttgatt cctgtcgcgg ttaaaccgct gtttcgatag gatcaccgta
    14221 atattgccgg atggtgacga ttacgcgcaa tccggcaata ataggttaca gtgtcacgtt
    14281 tttttatctc ttaaagcacg cactgctttt gcggctggcc tcttttgtcg caaaatagtc
    14341 gcccgtgttt cattgcccat ttctgctcat gcatcatcta cacatctatc cggatctgcg
    14401 cactatgttc cgccgtctgc ttatcgcaac agtcgtcggt attctcgcgg cctttgccgt
    14461 tgccgggttt cgtcatgcga tgctgctact ggagtggttg ttcctcaata atgactccgg
    14521 cagtctggtc aatgcagcga caaacctttc cccctggcga cggttgctaa ctccggcgct
    14581 cggcggactg gcggcgggtt tgttgctgat gggctggcag aaatttaccc aacaacgccc
    14641 tcatgcgccg accgattaca tggaagcgtt gcaaaccgat ggacagttcg attacgcagc
    14701 aagcctggtt aaatcgcttg cctcgctgct ggtagtaacc agcggcagtg caattggtcg
    14761 cgaaggtgcg atgattcttt tagctgccct tgccgcctcc tgttttgccc aacgttttac
    14821 gccacgccag gagtggaaat tatggatcgc ctgtggggcc gcggcgggaa tggctgcggc
    14881 ctatcgtgcc ccgcttgctg gcagtttatt tatagccgaa gtgctgtttg gcactatgat
    14941 gttggcctct ctcggcccgg tgattatttc cgccgtcgtg gcattgctgg ttagcaatct
    15001 gattaatcat agcgacgcgt tactctacaa cgtacaactc tcagtgacgg ttcaggctcg
    15061 tgactatgcg ctgattatca gtacaggtgt gctggcaggt ctgtgcggac cactgttgtt
    15121 aacgttaatg aacgcctgtc atcgtggatt tgtgagtctc aaacttgcgc cgccctggca
    15181 actggcacta ggcgggttga tcgtgggtct gctttccctg ttcacacctg cagtgtgggg
    15241 caacggctat agcaccgtac aatccttttt aaccgcccca ccactgttaa tgatcattgc
    15301 cgggatcttc ctttgtaaac tgtgtgccgt gctggcgagt agcggttccg gcgcacccgg
    15361 tggggtcttt acaccgacgc tatttatcgg tcttgccatt ggcatgttgt atggtcgtag
    15421 cctgggatta tggttccctg atggcgaaga aattacactt ttactcggat tgaccgggat
    15481 ggcgacactg ttggcggcga ccacgcacgc gccgattatg tcgacgttga tgatatgtga
    15541 aatgaccggg gagtatcagc tactccccgg tttattgatt gcctgcgtaa ttgcgtcggt
    15601 aatttcgcgg acgttacacc gtgactctat ctaccgccag cacactgcgc agcatagcta
    15661 agcggatgta ttgccccagt tcacgctgtt cggcgcgcgg cagataaggc agttcaccaa
    15721 tgagcggtgc cggaagtttt ttacccagca catcaatgat ttccgcataa tgcgccagtc
    15781 ctgggttgat tcggttagcc acccagccaa tgagcggcag cccgtcgttg gcgatcgcct
    15841 gagctgttag cagtgcatgg ttaatgcaac cttcctgaat accgacaacc atcaacaccg
    15901 gcagttgttc ctgcactacc cattcagaga gtggacgcaa atcattcatc agactgcgcc
    15961 agccgccagt cccttctacc acgacatgat cgactttttc ggtcaggttt gccaggccgt
    16021 ttgaaatgag ggtgtaattg attgggcaac tgtgcgccac gctactttct tcttcgctta
    16081 acgcgatagg attaactgct tcataaggca gttcgatggt tgaaacactc tgcaacacca
    16141 gggcatcttt attacgcagc ccttcgggtg tctctttgct ccccttcgct acgggtttat
    16201 atcccgcaac cgtttttccc tgggaggcta acgcttgtag caatgcgcgg gaaaccaccg
    16261 ttttccctac agaagtgtct gtaccggtaa taaagaaacg cttcagcatc actaactcca
    16321 ccgttatgct tcacaaatat aaactaggaa aataattaac cttgaaagtc taagttatgc
    16381 tttcctggcc caaattgaga tagcgcaaat tttggtagaa cagttaaaaa atgttaaccc
    16441 tgcaacagac gaatcaacaa agaaccgtta tacatcgcgt cttttaccag tgcagcccct
    16501 gccatcgtgc cctggttaga aaactgagta ctctcaacgc tgatgtgctg actatacgca
    16561 ggaagggcct gctgacggat gctgtctgag atgaccggga agaggatatc tgccgcttta
    16621 cttaacggtg agccaatcag tattttttgt gggttaaata aattcaccat gatggcaaga
    16681 atgcgcccta catgcgcgcc caccccggta atgatgtctt ttgccagcag atcgccgcgc
    16741 aatgccgcct gacacaatga gtccacggtt aacggttgtc catgtaacat cgagctcatg
    16801 gattgattaa gacgcagctg tgccagctca agaatactgt ccacactggc gatggtttcg
    16861 aggcagccgt gattcccgca ataacagcgt ttcccatacg ggtcgacctg tgtgtggcct
    16921 atttccacga gactactgct gcctgcgtgt agcagatgac catcggtaat gacgcccgcc
    16981 cccacgttgt gatcgataac cacctgaatc acatcgcgcg ccccgcgtga ggcaccaaac
    17041 aaggcctctg ccatcgtcca tgcgctgata tcatgctgaa tataaaccgg tacgccggta
    17101 tgctgctcca gcgcctcgcc gagcggcatc tcttttacat cctcgtagaa cggcatgcga
    17161 tgtacaatac cattttccgt atcaataatt cccagcaagg ttatggcaat cgaagttaga
    17221 cgctcaagtt ttttctggtg gcgaataaaa aactgatcga tatgggaaat gatacgatcc
    17281 agcaatggcg agtcatcttt taacgccagt tcctgcgact cttccaccac cagtttgctg
    17341 ctcagatcgc gcagagcaag gaaaatctcc ccgcgactaa tgcgcagaga aagatagtgc
    17401 caggcttcag tttcaaccac cagccccacc gccggacggc cacggttccc cgcttctttg
    17461 atttccagct cttgcaccag gtgtgcttcg agcatctcac ggacaatttt agtgatactg
    17521 gcaggagcca gctgcgccag acgggaaaga tcgatacgcg agactggacc aagctgatca
    17581 atcaggcgat aaaccgcgcc cgcgttggtc tgctttattt gatcaatgtg cccaggctgg
    17641 ttttcagcaa ccaccgcata ctccctatat tttcgcgctc cgaaataatc tgtaggctat
    17701 ggtgaagcac ttcaatacgt gtcgtcaaat ttttacttag gcatgtgatt aacagcacat
    17761 ttttcgggct ttttcgctga aatttccctc acctgagagc attcagcaga tgaatacgaa
    17821 agtttcgcgc agctggactt tgttcatgat gtttcggcca gaccaaccac atttcagaaa
    17881 ccgcatcctc ttctgcaatc ggcacccagc gcatttcgtt gagctgaaca cgtttaaatg
    17941 acgcaggcaa aattgaaaca cccagaccgg cggaaaccag accgatgatg gtcattgcct
    18001 cgcccacctc ctgagtgatg acgggcgtca aatggtaacg tcgcatcagc ccgagaatat
    18061 cttcatacag ccctgtcccg acgtgcggat caaaaaagac gaagggttct ttcgccagtt
    18121 cagccagcgt tacattcggg ttatttgcca ggggatgatc gtgcgggatc atcgccataa
    18181 gcggttcatg gacgatgact gcgtgttcaa gcgtctccgg taacgctgtg ttacgcagca
    18241 atcccatatc cagcgttcct tcaatgagcg gagcgatttg ctcacgagtg ttcatttcgc
    18301 gggtttgtaa atggacatcg ggataatcac ggcgaaacag cgataacgta tcggacaccg
    18361 cccgaataaa aggagcggac gaagtaaaac caatgcgcaa ctcccccgct tccccctgat
    18421 gcagtctttc agcgcgagcg gcagcgtcat ctaccataga caggatttgc cgactatctg
    18481 caagaaactg ttttcctgct gccgtcagca atacactgcg attagttcgt gccagcagtc
    18541 gggcaccaat ttgttgctcc agtgcctgaa tctgctgact tagcggtggt tgcgaaatat
    18601 tcaggcgggc agcggcgcgc ccgaaatgca gctcttccgc aatagcaaca aagtaacgca
    18661 gatgacgaag ttcaatattc atatttaaaa catcttattt gagattatta atatattaga
    18721 cagaacaatt cgattttcct aacctatgta taagcctgat ccacaggcat atttagcaag
    18781 gatttcaagt gagccgtact acaactgttg atggcgctcc ggcaagcgac actgacaagc
    18841 aaagcatttc tcagccaaat caatttatta aacgcggtac gccgcaattt atgcgcgtca
    18901 ccctggcgct gttctctgcc ggactggcaa catttgcact tctctattgt gtgcagccta
    18961 tccttccggt gctttcgcag gagtttggct taacgcccgc gaacagtagt atttcactgt
    19021 ccatttccac ggcgatgttg gctattggtt tgctgtttac tggcccccta tccgatgcca
    19081 ttggtcgcaa accagtgatg gtcacggcgc tactgttggc ctccatttgt acgttacttt
    19141 cgacaatgat gaccagctgg cacggcattt tgattatgcg cgccttgatt gggctttcgt
    19201 taagtggcgt ggcagctgtt ggcatgactt atcttagcga ggaaatccac cccagtttcg
    19261 tggccttttc gatggggttg tatatcagcg gcaactcaat tggcggcatg agcggacgct
    19321 taattagtgg tgtcttcacg gactttttca actggcgaat tgctctggcg gcaatcggtt
    19381 gtttcgcgct ggcctcggcg ttgatgttct ggaaaatcct tccggaatca cgccattttc
    19441 gcccgacttc gctgcgccct aagacgttat ttatcaactt tcgtctgcac tggcgtgacc
    19501 ggggattacc gttattgttc gcagaaggct ttttgctgat ggggtcgttc gtcacgctgt
    19561 ttaattacat cggctatcgg ttgatgcttt ccccctggca tgtcagtcag gccgtggttg
    19621 gcttattatc gctggcttat ttgaccggta catggagctc acccaaagcc ggaaccatga
    19681 ccacccgcta cgggcgcggt ccggtgatgt tgttttcgac gggggttatg ctgtttggtt
    19741 tactgatgac cttattcagc tcgctgtggc tgatctttgc cggaatgtta ctcttctcag
    19801 caggattctt cgctgcccac tcagttgcca gcagctggat tggcccccgc gcaaaacgcg
    19861 ctaaaggcca ggcctcctcg ctgtatctgt tcagttacta tctggggtcg agtattgccg
    19921 ggacgctggg tggtgttttc tggcataact atggctggaa cggcgtcggc gcatttattg
    19981 ctctgatgct ggtcattgct ctgctggtcg ggacgcgttt gcatcgtcgt ctgcacgcct
    20041 gaaaaataag cccggactgc ggtaactacc cgtccggact tattgcttgc tcaaaccaac
    20101 gttaatagcc atcctaaaat agacgaagcg ccagccaatt cccgcagcgc gtctagcgtc
    20161 atcaggatta taagtaccca aataaacgga ttcattttgc tgtgtgtcat ttattactga
    20221 tgcgcagtta ttctaccgct ttgtaagtag taaaatagtt aacccgatca agactactat
    20281 tattggtagc taaatttccc ttaagtcaca atacgttatt atcaacgctg taatttattc
    20341 agcgtttgta catatcgtta cacgctgaaa ccaaccactc acggaagtct gccattccca
    20401 gggatatagt tatttcaacg gccccgcagt ggggttaaat gaaaaaacaa attgagggta
    20461 tgacaatgaa aaaagtatta gctctggttg ttgccgctgc tatgggtctg tcttctgccg
    20521 cctttgctgc agagactgcg aacacacctg ctccgactgc gacgaccacc aaagcagcgc
    20581 cggcgaaaac tacacatcat aaaaaacagc ataaagcagc acctgcccag aaagcgcagg
    20641 cggctaaaaa gcatcataaa aatacgaaag ctgaacagaa agcccctgaa caaaaagcgc
    20701 aggcagcgaa gaaacacgcc gggaaacaca gccatcagca accggcaaaa cctgctgcac
    20761 aacccgcagc gtaagttttc aacagtaatg ctggcgcgcc ccctcgcgcc tgaaaattac
    20821 ggtgctaagc gggtaacgtt tagcaccgcc tttagcggag ggtagtatgg tgggccgtta
    20881 tcgctttgag ttcattctta tcatccttat tttatgcgca ctgattgccg cccgttttta
    20941 tctttcctga ctgtagttat ctgattttac tcccactttc atcccgtccc gtctatagta
    21001 tttatgaggg tttgctttta ataatcataa ttacccacca gagtgtgata tgcgtacaac
    21061 cattgctgta gtgttgggtg caattagttt gacgtctgct tttgtgtttg cagataaacc
    21121 agacgttgcc aaatcggcaa acgatgaggt cagcaccctg ttttttggtc atgatgatcg
    21181 tgtgccagtg aatgacacga cccaatcacc gtgggatgcg gttgggcaac tggaaacggc
    21241 cagcggcaat ttatgtacgg cgacgctgat tgcacccaat ctggcattaa cggcaggaca
    21301 ctgtttattg acgccgccta agggtaaagc ggataaggcg gtagcgctgc gttttgtgtc
    21361 aaataaaggt ctttggcgct atgacatcca cgacatagaa ggccgcgttg atccgacact
    21421 gggaaagcgg ttaaaagcag atggggatgg ttggattgtt cctcccgcag ctgcaccatg
    21481 ggacttcggc ttgattgtgc tgcgtaatcc cccttctggc attacaccgt tgccgttatt
    21541 tgagggagat aaagccgcgc ttactgccgc attaaaatcg gctggtcgta aagtgactca
    21601 ggcgggatat cctgaagatc atctcgatac gttatacagt catcaaaact gtgaagtgac
    21661 tggctgggcg caaacgtcgg tgatgtcaca tcagtgcgat accttgccgg gtgacagcgg
    21721 ttcgcctctg atgttgcata ccgatgacgg ctggcaatta attggggtgc aaagttcggc
    21781 tcctgccgcg aaagatcgct ggcgcgccga taaccgggcc atttctgtta ccggttttcg
    21841 cgacaagctg gatcaactgt cgcaaaaata atgttcaaac gctgcccgac agtgcgggca
    21901 gcgtgttcat caggcaagtt tcaccatgat cattccagcc aacagcaaga ccaggccaat
    21961 ccagccttta cgatttaacc gttgaccaaa caagatccaa cctgcggcta acgtggcggc
    22021 aataccaaac ccgccccaca atgcataagc gacagacaag tcgatccctt ttacggcctg
    22081 agaaagcgca ctaaaggcag ccagcaccgc cgccagggag agcaagccaa atattttgcg
    22141 acgaaagccg tcagaaaatt tcaaaaagac gttagcaacg atttccagca cgattgccaa
    22201 tgccagccag gcggcgtgaa cccattcaaa ctgcgccatg gttcacctcc agttcaggtt
    22261 tacgcgcttt acgggtacct gattttatca acacaatccc ggcgaccagg gtggttaacc
    22321 cggcaatttt catcagcgat aaactttcgt cgaataacat aacgctaaac aaggtaataa
    22381 ataaaatacc gataccttcc cacagcgcat aagctacgcc taaggcgatt tttttaacgg
    22441 cgaaagagag aaatatatac gacagagaaa tcatcaccag cattaaaata aagccgccat
    22501 ttccctcact gacgctcgcc catttcatgg acagcgtacc ggtaatttct gtagcaatag
    22561 ccagacctaa taaaatccaa taaatataca ttgtccttct cctgcaagag aattatttta
    22621 attttcgctt aattcagcga aaccaaagta aagtggtcaa gccccgcgca tagggcaagc
    22681 ttaggcagaa gaaaggacta aagcgcgttg cgccagtgct gctcacctac gagcaagata
    22741 gtggatgagg tacgaagatg ggtaaatgta gaaaataacg tcctgaacaa attgtccata
    22801 atattacaat tatccgcagt gttgcttctc gtcatcgcgg atgataattg tcctcggtag
    22861 ttgaacacgc ctgatttgta tcatagctta agaattaact caaaatattt tcacttcttt
    22921 acctgagcgg tttgattttc gttatgatga cggagcgaaa aagacattat tattagcaaa
    22981 ggaagaaaaa acggggacaa gcatggcaaa gccgatcatc acgctcaatg gcctaaaaat
    23041 cgtcattatg ttgggaatgc tggtcattat tctctgcggt atccgttttg ccgccgagat
    23101 catcgtgccg tttattctcg cattatttat tgctgttata tataacttat ttcacttaac
    23161 gcattgattc aattaaataa tttacacaac aaaaagtgcc aaaaatcgca aaatgactac
    23221 accagtgact acaccgttcg gtgcactgta tgaaacaacg tggaacaaat agacacaaga
    23281 aatataaagg cgggtcatct ttccaggggg aagcgcacca attcatgagg ggcgttaatg
    23341 tcgatatggg gatccccacc taccggaatt tttgccaggt taaatgttaa tcaggctggt
    23401 gggttttaca tacccttgat cacggtaatg atgattcagg tgcgtacctt ttccccagtg
    23461 gggtaaaagc tccaaccgta acgatgttcg ttgtagttgc cttgatggtc tgcgtggtca
    23521 ttatgaccat tcagccaatg accttaatca gaatttttcg ctaaaaaatg acgttggcca
    23581 cgtcatccgg aaagcacaaa atcacgtcga tttttaatgg atggttaaac cgtctttatc
    23641 tcgatatccg tacgtattac gtacgcagtc gttccggctt cttccagtgg tacgtaattt
    23701 ttgctttttc cctgtacgtc tgcacgcggc gacggtaggc cagcatttca agaacgcgga
    23761 tccgtatgtt gcgcatatcc acatcattaa gctggatacc atcacggcgc atcacctccg
    23821 cgacaacacg cgcataattt tcggcggtca cgctgtccgg ctgcgtggcc tgttcgtcat
    23881 gctgctggct gattccagag acgcggcgga ttaatcgcag tatttcggct tctgtcatgc
    23941 tgctgacctc attacacccc gctaaattct tccagtttct ggcggtggct gtcgcttata
    24001 tcaaaagcaa aatcctcatg ctctgcctgg aatgtaccaa acgccatcag tgccgccacg
    24061 ctcgggtcta tcttgttcgg tgattttttc ttgttcggct tgatattggc gttcgcgtca
    24121 ctctgcatca cgacgttact catcgaccag gacaacaccg gatcaccacg atgcacgata
    24181 accctgcggt taacaaaaac ttcgaacgat ttcgccgccg gactgaatcg aaggtaggtt
    24241 tgcgggaacg gctccacctc aaagcctgcc ccctgtaatt gcgtcctgag atgcgttgcg
    24301 ttccacgtat cgaagcccac cagcctgata ttaaattttt ccgcgtcctg catgatgtca
    24361 tcacgtatcc ggtcgtaatc aatgcagtcc cctggcgttg tgcgtatcca tcccgcccgt
    24421 gcccactggc gatagatagc gcgattttta ttggctgggt tctgtaactg gaactccggc
    24481 agataatgac gggaaaccag catgatattt ttaccgaccg gaaaggcata gcacacgctg
    24541 gaaatgtcgc ttgtggatga taaatccagc cccgcgtaac attcctgacc gtgtaaatct
    24601 tcctccgtga actttccggc gcactcagcc catgctccgt tacccatcca cggggtagcc
    24661 ccctgacacc agatattaaa tcgctttgtc atcatctcca cccattgcga cggtatgccc
    24721 cgcgctttct ggatggttga ggccagtttt tcacgatcca cggaaacatc aatattaggg
    24781 ttcgccttta tccacatctc cggatcatca acctcgtttt cgtcgtccag ttcgtaaatc
    24841 agtacaaaaa ttgaatcgtt gacctcttcg ccgtccagga tctggcagca ataatcatag
    24901 tgctgtttac aggctgaaac gacgttgctg cctgatgtgg taatggcaaa taacagccct
    24961 tcgggacgtg cccccatccc cagttcaagc gcagaataaa cgccgttatc ggggtgtaag
    25021 tggtattcgt ccacaatggc aaggctgggg ttagtaccct cgatggttgc cgcttttgct
    25081 gccagcggct ttaacaggct gttgcttttc gggtgcatca ccttgtgggc ctgaatattc
    25141 actctcttgc gtaacggtcg ggataaaagg cacatctgac gcgcatcatc aaaaacgatc
    25201 cgcgcctggt cgcggctcac cgctgcggtg taaatatcct gctgcccgtt ctccataatc
    25261 agaaaccagt tagccagaat cgcggctgtc gtggatttcg catttttgcg cggtacttcg
    25321 ataaaggcgc tcgtgtattt gcgccttccg gtggccttaa ccttaaagcc gaggatgcac
    25381 gcaaaggcaa actgctgcca cggttccagc tcaatgggtc ttccacgcat cggccctttt
    25441 acgtgcgggc acaccctgga aaagacaata aaccgctcaa caacctcacg atcgaacatg
    25501 taaagggagt tttcaaggtc cgaaaagtat cgtttaacgg cctgtttcag ccgtttacag
    25561 gccggaatct tgcccgtttt tacgtcttct gcgtacttat tccaggcggt caagctcgtc
    25621 ctcttcttct gtttccggtg gatttttacg gcggcttatc gggtcaaaac cgagcaaaga
    25681 ggccattttt atcatcactc tttccgcgtc ggatttcgcg cttaatgcgg ggtttctgct
    25741 ctctccgccc tgactgttaa caatgctgaa cccgcgcgcc gcaaggtctg cgacggcttt
    25801 ccggtatatc gagtaattga cgcaatacag ttccagatta ctccagtcgg caggggtcag
    25861 gtctccccgt tccgcaagct gccgcgattt ttcccgccac tgcttcacgg cgatatcatc
    25921 caggtaggcg ggggctttcg gtggtcttgc catgcttatt ttttcgccag attatttttc
    25981 aaaaaattac cgtgcataaa aatttgggga ggcgttcggt tctgggcggg gtcgggttcg
    26041 tcctgaaaac tccccccacc ccgtccggct gcctcatcag cgattgcgga aacattccat
    26101 aacctcgcgg tcacggtcgt ttaatcgcgt cgctgtgatg cgttctgcgc gtcctgatgc
    26161 tttatcttta tgccctgctt cctgtgcctt ccatgcgtca cgctgcctta taagtccacg
    26221 gataaggcgg ttttgttccc gctcattcat cagcgccata catccagtta ttgcggttag
    26281 cgccccgttc ttcctcctca cggaatccac ccgcagcacg cttgtttttt gtggacggat
    26341 caagccattt cgttttctgg ttatgacacg cctggcacaa tggctgatga ttccactcag
    26401 gccagaagag aacatcatta ccgccatcga ttgggataat gtgatccacc accacggcgg
    26461 gcgtgtatat tcctttttcc aggcaatgcg cacataacgg gtttttactc agatacatgg
    26521 cgcggtattt ctcccactgc ctcgtatacc ctcgctccct gctgctgcct ctccggctgt
    26581 cctgctgctg gcgtgcgctg cgtctgtgct cctcacactt gccggacttc acgcgcctgt
    26641 tgcagcctgg ttctgtacat cgtcttaatg gttgccacgg catcagtaca cccccacatc
    26701 acggtaagcc gtccagagtg cgccaatcgt catgggtacg tgtgtttttg cgttatccgc
    26761 gacaatctgg cgattttcat acaggtgagc gataaacatc atgcagccaa tctttatggc
    26821 tggcgtgaac tccagcccgt catcaaagcg cctgcctatg tgtatctggc acgcctcaag
    26881 cgatgcggca atgtatccgc tgattaactg gtcttcatcg tcgccatcga tgcggcaatg
    26941 gagtttcact tcttccaggg tgataagttc tgtcattttt ccgcgccctc actacaaaga
    27001 atttcaaggc gtgtcctggc ggcatctggc agcggttgcc cgatgatatt cagtacacgc
    27061 cccgccagcg gccccgtatt gacctttatc cgactggtgg cgttgatgtc cttccggtag
    27121 cgtatccata tccttacagt tccagtcgcc agctctgcac ctgatgaaat ggcctccttg
    27181 ctgctgatca tgttcacgct tgcccagagt gtgtgaccgt ccacccacgt ttcgagtatt
    27241 tcgcccgtca tggctctggt ctgtttcagg gtctgaatcg ttaccctgtc acgcagtcgc
    27301 cctatgttca ttccggtttt tctccctcgc tgatttttac ttcctgtttc catgcctggc
    27361 tgaactcatc accaccatca cgcggtgaca gtccttcacg ttcgcgggct tcgttcggac
    27421 acataacgcc ggatttgatg ccgcgctcat aggtggcaaa gcgttcgcca ggtgtggccc
    27481 gtaacaggtc cgcgctgtca aactccacct gataccggat accaggtaca ggcgaggcca
    27541 ccagcagggc gttttttatc tgctgctcaa agttcgccag ccacgggcgc atcgtcatgg
    27601 tgagaaatgc gcggcttgcc tcgctgaaat tgctgtaggt gctgttgctg tattcctgca
    27661 aaaaaatcgg cgagacgttg aacattcggg cgatgtcttc aatggtgaag cgacgggagg
    27721 ccagccattc agcatcctga ttactcatgc ccagcttctg atagctcata cccccttcaa
    27781 ggatgggcgt ttttccggcg tttctggccc ctttgtagcg ttccagtgcg gctaatgcct
    27841 gtttgccctt cacgccgtcc agccattcgc ctgacgtgat aacccctgcc gccatcatgc
    27901 catcacgcat cacgctcgcg ccgtggcgtt gttgggccag cccaagcccc agcgattcgc
    27961 ggcaaatggt tacaggtgag cgccccataa aaccgtcatc cgtggagtaa cgaaggtgga
    28021 gaacctccca cggtaaatag ttgcgggtgt ttccggtgta agcgtcagtg atgcagtagc
    28081 gccagttgtg ttctcctgtc tgctccacgt tcaccgactg cggcgggtaa ggatgtaaag
    28141 ccgccggaaa accatcacgc ccccactgaa tcaccgcgta agcattaccg tttaacaggc
    28201 agtggcggat catcattcgc ttaaactggt agggagtctg ccacgcgttc gggcgctcgt
    28261 tgaggatgtg atcgaccgga tgagaatcaa gccactcgcg ggcctccttc cccttctcat
    28321 tgcgtaccag gtacaggtag catggcatag tagccaccgc ctcagagatg accgtgacgg
    28381 cgttcatgac ggcggggagt gattccgctg tccccgatga tacgtactca cccgcccccg
    28441 tgttcgatgt gccagccagc gccataaatt catcaagcgt catgctgcgc tgctcttttt
    28501 ttcttctgaa aggccacata tcacaccccc gctaaatccg cccaccagcg gcgattatcc
    28561 gcacgcggca ttttttcggg gtgctgctca tacagggaac ggcgggccag ctccacgccg
    28621 gaatcggggt aagccggtac ggatgtaacg gtaatttcgt acagttccgc caccagcacg
    28681 gtgcgcacgc atggatctgt tgtggtatcc catacatcct tacgggaacg aaagccaaag
    28741 ctcatgccgg atatatcacc acgtttaacc agttcgataa cgtcacgccc tgtgctggta
    28801 tccggtgggg taagttcaaa gcgtaaccct gtgtcgtcct cttccagttt cagcgtgcca
    28861 gaacgggtgc gccccagtaa catgctgtgg tcatgctcat acaggccgcg aacgtcatta
    28921 cccgccgcaa gccactcagt aaacgccccc cgctggaatt tttcgtaaaa ctccccccat
    28981 aacagttccg aaaggttatc ccagcgaaca acgtaacccg tcagcgtgtt gctggcgctg
    29041 gtggtgattt ccgatgaccg gatttccata ctcttcataa tttttttcac ccataaaaca
    29101 ctaaaggggc tttttagccc cttctgtatg ctgttaatcg tcgtcctgtg gcagttccag
    29161 aatcttgatc gcgttcgaat ccaccacgcc accgcctaaa tatttctgcg tgaaaatttt
    29221 gatgaatcct ggttctgtca ggttgtccgg tctggtgcga acacccgttt cgtgatcaac
    29281 aatgtagtaa ccgcgtttga agtcacccag ggcaataacg ttatccggca taaactccag
    29341 atattcgacc ggaaggccca gcaacgtatc aggatcacca gcctgtaaac ggtcgcgcca
    29401 gatgtaatca ccgttcgcgt tcttcacctt ctgaagtttt gccgccgtcg tggagttaac
    29461 cacccagacc gcgtttttgc ggtatttttt acgtaatgca aatttcaggt cgatcagcgg
    29521 gtccgcagat gtccacgcaa gagactcaga aggcttaatt acctgcaacg taccaaaatc
    29581 acgttctttg tcgttcttct ctgcacgggg tacggataaa aagccttttg cttttttgtc
    29641 accgtcgccc acaaccagat cgctttcttc ggtttccgtg aaggtgtcgc caatctcacc
    29701 cgtcagccat gaaaggatgt ccacatcgga aaaatccacg atttcctgtg tggtgcgcgg
    29761 gtacgcatag accggataca gcttaatgct cacctcgtta atctgcgggg tgctggtctg
    29821 ttcgcgtgcc ttaccctctt caccgtggtt aacggtcgca ccgccagcgg aaacaagctg
    29881 cttaaactcg ttgctgctga ttttcttcac ggtacagatg cggcgcatgg tggattcatc
    29941 cgccagcatt cgcatgattt cggtgttcag ctcggggata acggtataac caccatcagc
    30001 gggaacgcct gtacttaatg cgcgggtttc acccgtcaga atgtagtttc gtagttctgc
    30061 ggggtcagtg gtctggctgc ttttacctgg cttgctgcgc tcttcgtctg caatggcttc
    30121 aaggcgggaa atgtctttat cgagggattc agctttagcg cgtaattcgt caaattttgc
    30181 gccctctgca tcgttaaggc tgcggttttc tttttccgcg ttctccagca tgtcgcgcat
    30241 ctgattttta atggcggttt tctgctggcg taattcgatt attctcggca taaaaaaagt
    30301 cctggggtta agtaaggaac tccaggacgc ggcaaaaact caaccgtttt tcataaggaa
    30361 atcagcaatc gcaccgatcg tttttccgcc tggtaatgaa tattggtgag cacattaaca
    30421 ggcgggaaag tggccccagc gtcctggcac cactggcgag aataatcatg attcagggcg
    30481 ggtaaaatat gccgatccgg tcaatgaaca acgtggaacg accacgaaca aataatttac
    30541 aaaaaatgac aaaaagccgg attgctccgg ctgtatgggt gctcagtccc tgatcccttt
    30601 cagaaattct atcaatgcat ctatctgttc aggatttact gccagcattt caccggatag
    30661 cgcacatctg acaaatccat gccgatcctt ttcgattagc gcgcccgttt ccaggaatgc
    30721 gcggtaatca ttgatgttca tcgtctccat gttgtcagca tggtatttat cacgctgttt
    30781 taatatctca tcaaatttca tcggcattgt tttttcctct gttgtgtctg tttgtttcag
    30841 atagtaacta tgccggaccg tgacgaaaag ccggtaatgc gccataccgt ttcaactggc
    30901 gcaaaaaaag ccggatttct ccggctgtgt gattagctgt cctggtaatt gcgccgtatt
    30961 tcatcaccag caccatctat acccatttcg gcacaagtgc gattaactgc atttctcagg
    31021 tctccgaaat tatcaggcgg ctccggtggc ctctgtgcct tcctggaaca ttccagccgt
    31081 cgcatcgtga tgtgatgccg ttccttgtct gtctccacca gcatcatgac ttcaccccat
    31141 cgcgccgccg ccctccggta aaatcctttc gcttcgagtt cttccgctat gcggtcatgt
    31201 accatcgtca ccccctcaga acggaatatc atcaccgtaa gggtcatcgc ctcccgctgg
    31261 tggctgatta ccctgtgtgc ctgtggtttt gcgtctgctg ccgcctggtc gcaccgtttt
    31321 cgcactgatt acgctgtcgg caatgacctg ataaccctga cgcgtctccc cgttctgtcc
    31381 ggtccactgg cttatctgca tcgtgccgga tacgctgatt acgttgcctt tctcatgtcc
    31441 tgccagttgg tcggcctgtt tgcaaaatgc caggaccgac agccataacg tagcctgccc
    31501 gtcctgcgcc tgactgcatg gcagtgatac cgccatacgc gccagcgtca tcggtgtgcc
    31561 cttgctggtc tgttttacct gcgggtcgtc caccagccgc ccgtaagctg caatttgtgc
    31621 tgtcatattg ccacctcagt gaagcgatcc ggcgttgttc tttttcatct cttccatcat
    31681 tttttcagtg agcattacgc actgaaaacc catgtttttg atgtctacgg gtttcatgcc
    31741 tttgtcagtg gatatcacag gcagaatatc ctgatacaca tcgcggtcag ggtaactaag
    31801 cacacaaagc gcccatgatg ccacgggtga ggatccttcg tctgtttcaa cccaccagcc
    31861 tggtgtagct gcgcttattt gcagaatcgt gatccgtccg ttgtgcttgt aaaatttttc
    31921 accaaatttt ggttcgctca tgattccacc tctccggttt taacgttgat ggttgttacc
    31981 tgttccgctt cggcaatctc ccgttctgtc agcgtggcaa agtttgcagc tgccgttgtc
    32041 atgaatgcgc ttattagttc gggattctcc ttcgcgtatc cttcccgtgt gtggcggtct
    32101 ataactttga ttgccacctt tagggaaagc tctgtcatgt ctaacgcttt atatttttgc
    32161 tgtgttctgt ctctgcgcat tttggtcatt tgtcgcccct gattcatgtt ttcggtcggc
    32221 atgtttgtta agtgattttg atgtatgcac atttattttt accccctcgt ttaaaaagtt
    32281 ttaggttgtg gtgcacctcc tctacctctc tacctaatca tctttcaggt cagtaatggc
    32341 gcggctttca gatgggtaga gggctttcgt ggccctctac ccatcatcta cccgcccctc
    32401 acaaacaacc ttaatcatgg tggagggggt agagggcttt tatttgcctt ctaccagccc
    32461 ctctacccac ttatcatatt gaataatgta tatttatttt ctttaggtag aagaggtaga
    32521 gggcttttgt ctaaaattat aaaaacgcgt cgcaatcctc tgttgttgtc acattggttt
    32581 gcgtaagtcc tttaaccctg cgcgttatat attcacatcc gtaaactttt gccgctggct
    32641 tcatggcctt gctgaaatca gccacgttta gcggcttgct tcttcctgcg tatgccataa
    32701 acgccagata gacgcggtaa aggctgtttc tggtcgtgta cttcacggaa tcgccaccgc
    32761 cacccatcat caggccgcgc gcttcctcca gaaaattcag gaactggcaa aactcaataa
    32821 ccggatccgt ctgttgcttt attgccagtg cttcatcacc gtcgcgctgt tccaggagta
    32881 aagcccgtgc cttttcaggg tcggcaaagt tcgccagtaa tcggcggata atcacaggga
    32941 tttcagccgc gaccttctcc ggcaaatcct tgtccttttc tgcctcgcta acgatattgt
    33001 caaagcgaaa aataacccga cgacgtgcca cgcctccggc ccgttcggtg aatatcatcg
    33061 ggttgttgtt ggtcgtcagc accaccgccc tgattaccgc cgtgaaacgc ttttcatatt
    33121 tcgggttaat ttccacgggg tcgccgcccg tgattttctt gatgcccgtt ccttcgcctg
    33181 tatatttcgg ctggtctgcc aggacgataa gacgactccc gacaacctgc gcacgtccac
    33241 cagcatcatc aagcgatgtc atttcagcgc ttaccgtgtt ctgtttccct gccagaaggc
    33301 tggctatgtg cgtgaatgta cttttaccgc ttccgccgtc tccggtggcc tcaataaaca
    33361 tctgccagtc gtaccggttc gccataatca tgtacagcgc ggcacatata cgcatcatct
    33421 tgcgcgggtc ttttccggct gcgtgctcaa gccatttatg aaaatttggc gcgttatcgc
    33481 ggatgttctc ccctggtgct ggtggcgtgt actcaatacc gttgtgcgtg gtgatccagt
    33541 tctccggcgt gtgcggggaa aattcccccg ttttcaggtc aagcgcacca ttggcgaacg
    33601 gcaacaaatc gccggacggc tcgcccattg gttcggcaat aacttttaac gcttcaacgg
    33661 cgttattgat tacgcgcttg ctgaaagtgg ccctgtgctc tgaatagatc gccaccattt
    33721 cgcggctaag ttccattgtg ctgaccggac accataaccc gccgcgccat acgtgaacga
    33781 tttcactttc aggatgtacg caaacgccat caaagcgatc ggaaagcagc tgagcgcgtt
    33841 cactgtccgc catctgcgaa agttgcgcct tttgctttac cggaagctca acgaacagac
    33901 cttcagaaag attctggcgc tcacgggcca gatattcgcg ccagttctcc acctcctgaa
    33961 cgtgcattcc ctcagggtaa aaatttgcat cctgtacacc tgccgccgcc agcttctgac
    34021 caatcgcctt tatcattaca ggttcaagat gtccggccct gaatatgcgt actgattttc
    34081 ggccttccgg cacaatttgc agcttatcca gttcggataa ctgctgatcc ccaagccaca
    34141 caggaggctc attatctccg gccatacgcg cgtcatgttc ctgccattgt ttagcgtgtg
    34201 accaggcatc actacccgca aaaataatga cttctgtttc tttgtgtttt atgccgcgtg
    34261 actgctgttt tacgttcggt gcaagtttca ttttttaccc ctgaatacgt tcaacatctt
    34321 tcttatttcc tgaatattgg cgcgtgcttt ctccctgctg gtgggcacgt tacgcggtac
    34381 agcctgcacc agagaaaaat cacggtcgaa ctgataaaca ggcataacgc aatcatattc
    34441 gtagccttca cggcggtaag ttacgcgccg ttcctccacg cccttaatca ttaccgtgcc
    34501 gccgtactta tcgcggtaaa tatccccgca catgaattta gtgcgagttt ttccgctggc
    34561 agttaagcca ggatatttaa gtttcattat ttttattctc cggtgtgctg ttctttatat
    34621 ctgtcgtgca ataggtctat ttcttgcagt tccattatta caggctcaag aagcgttatt
    34681 aatgccgtaa caattcttga tttttgtttg tcgcattcat tgtcgccaag tgtttcatgc
    34741 catatgcgca atatttccaa catattttca ctgtgagaaa gtgcaagaaa tgcgcggtat
    34801 attgtttcgt ggtaaatatc acgcatatta atccccgtcc gtcgtttttc ttaaaataac
    34861 ctctgtcacg aaatcagcat aatcggcggc gatattcagt acgtctattc cagttgattt
    34921 atattctttc gtgccaatta agaaaaaaga tgctctaatc agtttggata ttgacgaaag
    34981 cgcatcaccc gcatcatcag atacgccgga aaattcatgt ttcagggaat taaaacgatc
    35041 atcacgcata acccccccat tttcacaatc agcaataaga atatttttag cgtcattcat
    35101 cgaccgcgtg gcggtgtatc ggatacattc cagggcgaac aatgtgtatt cttcccgttc
    35161 ttccttttgt gcaagcactg ctgtgcattc aatatcaata agtgcgtgca tcagcgtagt
    35221 gagcgcggcg gctgctgcgt ccggtgtggt tttattctgc aacatatctt aactccactg
    35281 aacttacgta tttacacggg tttcctttta cctgtcgcac acggtaggaa tcgtttttaa
    35341 tcacttccgc tatttgccca aactttttta ccgctgtacg gcggctcttg tagcggtaag
    35401 tgtttatctc ccttctgctc attaccgctt cattgtgata tctggttatc actatcagca
    35461 cttcaaacat gacgcacccc ctgacgaata cgggcgacaa aaatcagatg tgcgcgcggc
    35521 aactgggcgc gggcttcgcg ttcagtggct gcggtaacgg tgtaaatatc aatgctgctg
    35581 tggtggcact gcataaagcg ccagacaaag taagggcgtg cggatacagc catgtgaaag
    35641 gctcccaatt taatgttaag gggtctcacc actacgctgc taaacggggt ggcgagacgt
    35701 aacagggtta gcagactggc aaattgggaa accagcgagc gcaaaggctc ccccgttacg
    35761 ccccgccata atgcgggtat gggtaggttt acggacacaa aaaaaccgct tatcggatat
    35821 gggcggctgt ccgccaattt attcaggctg ctaaacccgg tcgccatgtg ggcgacgggg
    35881 gaagcataca gccccgtgat aattttttgc aagcggtttt tacgcatgat gtgacccctg
    35941 acgaatacga gcggcaaata cagcaacaca acctgacggg caacggctac gcgcttcgcg
    36001 ttccgtccag gcggttacgt ggatgatttg agattctccg gcactcaggg ccagaaaacg
    36061 ccacacaaag gccgtttgtg tgtgtacaag gtgtggtata tgatttacgg caaccataac
    36121 ggctcctagt ttacgttgtt ggttagaagc cccgttactg ctcctacagt gcggggcttt
    36181 gctctttgta tttcaacaat ccttttggtg tgtttcatgt tatggacaca tgaaacacac
    36241 gtcaaggctt tttgtatttc tttttttgtg tatactgaaa cacaccgatg attaggagtt
    36301 tcagaaatgg caacggctaa caaaaacgca aaatcacaac tgacaaccgt cagagtccca
    36361 ctagatgtta tgcaagggat ggaatccgtt aagctggacg gcgaaagcaa tgccggattt
    36421 atcgtaaccg ccatgcgcgg tgaaatcgcc cgccgccagg cagaaggaag cggagaaaat
    36481 ccccttgtgt cttcactgga tgctttggct aaggtcgaac aaattggcat caaggcagcg
    36541 gaggatatcg ggcagcttgt caccgttgca cgcgaagaac tccagcgtcg caagacccaa
    36601 gaatcagaat aatcactatc agcgccgtgg cgtgaggtac tacggcgcat tgctttacag
    36661 gcgcacacaa tgaccaacga agaatcaacc gaaaaaacat cacctgcacg aaaaagacga
    36721 cgcagaaaga aagagcatga atcagaacga ttcgcgccgt gttcttttgc ccttgagaag
    36781 taccttaaag aatactcatc aaaggagaga gcttcgcagt tatggcaacg cactgaacca
    36841 gactgattgc attgcacacc agcctgatag cggctatcat ccccgtgctt atgtttggga
    36901 tcacacacac aaactgcgca gcgggttatc tgttcagaaa ggcggctcca tttcggggcc
    36961 gcttttttta tgcctgaaaa actccaattt tgttgttttt cagtttcacc agggcgaacg
    37021 aatccctgcc cacattcggg cgtatattca atcttcatgg ttatagctct gtgttcagat
    37081 gattgatgtg tggcggctgc gtgccgccag cgtgattaat gaactgcctt gcagctatcc
    37141 ttccaggcca gaacctcgga taaagaccag ccaacggaac gaccgccaag tttacgacgt
    37201 gatgggaatt gtccggcctt ttccatgcgg tagcgacacg tacggctaag gccggttagt
    37261 ttttcgcatt ctttttcacg tataaaccga tcagtgctta acactattgc cccctttcgt
    37321 ttcttaaaga gtcatcaggt gtcttattgt gtcgtattgt tcccgctaga gtgatgaatg
    37381 gcaaatgttg gtggcgcatg gtttacagaa agaggaataa taaggataaa atcatttaaa
    37441 ttcatgttaa tacaaaggca taaaatctcg ttttatgcct tttttctcac gctttaaagc
    37501 gtgattcgct aatgtataaa aaaccagtaa tataataaaa atcagcaact tataaatctg
    37561 tatgcttttt cgcctcttgt tcgtgattgt tccacgttgt tgcacattgt ttcacgttgt
    37621 atctgttcgc atatccagta tgcgcatact gaaaaaaccc gaaaaaaatt attttcttct
    37681 ggctacgggt agcgtggtta cgttttcatg tgctcccgcc agtatcccta accgctccgt
    37741 ccacatatcc agcgcatcac gtttcgcatc cagataacgg gaatggttat agactcgttg
    37801 catccctggc atctgatgac ctgtaagctg ctccacgacg tgaggatccg cgcctaaatc
    37861 gttcagcatc gttgtaaagg tgcgccggat gtcatgcagt gaccattgag ggtgttttag
    37921 cctcctgtgc gctaatctgc cgtactgcga tacgctggcc tcctgtttca cttcccccag
    37981 caataagccc gtgtgcctgt tctgctccac cagcttcatg acaaacggca ggatcgcttc
    38041 cggtatgggc cggaatattg cgaccttcgt tttgctgtgc tccttcggaa cggtccatag
    38101 catttccgta aaatcccact ccccgatctc cgataacctc agttctaccg ttctggcacc
    38161 gaagacaatc aggaggcgga ttaacgcgac gtagtaaggg gaaaatattt ttttatccag
    38221 tgcctgcaat aactcgccaa gttctttggt gcttaagaca cgctcgctta tatccggttt
    38281 tttcccaacg tccgcaacgt tcagatcgtc cagaacgttg ctgattgcat agcgccgcct
    38341 acggcagaac ttaagcgcct gtttgcacgc ctgtagcacg aatccggcag taacaggcgt
    38401 tcgctttgcc acctggtcaa aacaagccag ccagtgccgt agctcgcatt tatccagcgg
    38461 catagcacca atgtgctgta ttacgtgatt attaagtcgc cttttcaggg cgatataatc
    38521 cacgcggttt tcctttacgt aagactcaag ccagtaggta agcgcatcgc caaccgttac
    38581 gggctttaac gcttcctgta cggtgtaatt catctcatga cgtggatttt tcccctcagc
    38641 cagccatgcg cgacactgtg cggctttttc cctggctgct ttcaggctca gatcaggata
    38701 acttcccagc ttaatgcgtt cgggtcgtgt ctcccttccc gttccggccc tgtatgtgaa
    38761 ataccatgtt aatttccctg atgttaaata tttcacgctc aggtttccgc catcactata
    38821 aaacgtgttt ttctcagctg gcttaccatg aagtttcctt agcaatgtat cgctcagttt
    38881 gttcattgct ctgctcacgt tttaccccct ctttacgaaa aagtgactac accagtgact
    38941 acaccgatcg ttacacaaag ggctacaacg tgaaacaagc tggaacaagg aaaaacacaa
    39001 atctgttgat aatcaaaaac ataatgcaca acctgaaaca ttatgaaaca gcaaaaaaca
    39061 ctaaatgata aaatgctgtt attcttaacc cgctggtgca acacatggtc cgctggcgag
    39121 tgccgcgtgt actggcggtg tcgattttga tgaccatcat cgtgatggcg atggtgttgc
    39181 tattagctta tctgggttcc gcgctcaacg agttgacgcg gacgttaccg caatatcgca
    39241 actctattat gacgccgctg caagctcttg agccgttgtt gcaacgcgta gggattgacg
    39301 tctcagttga ccagctggcg cattacattg atccgaacgc ggcgatgacg ttgctcacca
    39361 acttattgac gcagttatct aatgccatgt catcaatatt tttattgctg ctgacggtgc
    39421 tgtttatgct gctcgaagtg ccacaattgc ccggaaaatt tcagcaaatg atggcgcgtc
    39481 cggttgaagg gatggcggcg attcaacgtg caattgacag tgtttctcat tatctggtgc
    39541 tgaaaacagc catcagcatc atcaccggcc tggtcgcctg ggcgatgctc gccgcactcg
    39601 atgttcgctt cgcttttgtc tggggattga tggcctttgc gtttaattac atccctaata
    39661 ttggttcagt tctcgcggca atccccccta tcgctcaggt actggtgttt aatggcttct
    39721 acgaagcgtt gctggtgctg gcgggatatc tgctgattaa tctggtcttc ggcaatattc
    39781 tggagccgcg catcatggga cgtgggctgg ggctttccac attggtggta tttttgtcgt
    39841 tgattttttg gggatggttg ttaggaccgg tgggtatgct gctttccgtg ccgttaacaa
    39901 ttattgtcaa aattgcgctt gaacaaacag cgggaggtca aagcatcgcc gttctgttaa
    39961 gcgatctcaa taaagagtga cggcctccgc agaggccgtc agggttacag agctttcagg
    40021 attgcatcca cgctggcttt ggcgtcacca aacagcatgt gggtgttttc cttgaagaac
    40081 agcgggtttt gcacaccagc atagccagtg ttcatcgaac gtttaaagac aatcacgttc
    40141 tgcgctttcc acacttccag cacaggcata ccagcaatcg gactcttcgg atcatcctgc
    40201 gccgccgggt taaccgtatc gttagcacca atcaccagta cggtatcggt atcagcaaag
    40261 tcatcgttga tctcgtccat ttccagcacg atgtcatacg gtacttttgc ttcagccagc
    40321 aatacgttca tatgtccagg caaacgcccc gcaaccgggt ggataccgaa acgcacgttg
    40381 ataccacgag cgcggagttt ctcggtaatt tcagcgacag gatattgcgc ctgcgcgact
    40441 gccatgccgt accccggagt aatgatcact gaatgggagt ttttcagcag ttccgctgtc
    40501 tcttctgcgg tgatttcgcg gtgctcaccc acttcctgat catcgccagt agaagagccg
    40561 tcggtgccga aaccacccgc aataacgctg ataaaggaac ggttcatcgc cttacacata
    40621 atgtaagaaa ggatagcccc cgaagaaccg accagcgcac cggtcacaat cagcaggtcg
    40681 ttgctgagca taaagcccgc agccgcagcc gcccagccgg agtacgagtt cagcatcgac
    40741 accaccactg gcatatctgc accaccgatg gaggcgacta aatgccagcc gaataccagc
    40801 gcaatggcgg tcattatcag caatgccagc acttgcaggc cgacgctgtc cgtgcgaaca
    40861 aatacaatca gcagcaggaa ggaaacgacc agagccgcca ggttcatttt gtgacggttt
    40921 ggcagcatca acggtttaga cgaaatcttg ccacacagtt tgccgaacgc caccaccgaa
    40981 cccgtgaacg ttaccgcccc gatgaagata ccgaggaaca cttccgtcag gtgaatattg
    41041 accagaatcg gtgccattcc cgcgtcatga tgcagataac tgttaaagcc aaccagcact
    41101 gccgccagac ccacgaagct atgcaggatc gccaccagtt ctggcatttc ggtcatttca
    41161 actttcttcg ccagacggat accaattgcc ccaccaatga ccatcgccag caagatccag
    41221 ccaacattac ccgtatccgg tccaaaaatg gttgcgatta acgcaatcgc catcccggcg
    41281 ataccgaagt tgttaccctg gcgagacgtt tcatgtttcg aaagaccggc cagactgaag
    41341 ataaacagga tcgcggcaac aatgtatgca gctgtaacta atcctccaga catatgttac
    41401 cccttaattt ttgcggaaca ttttcagcat gcgctgagtc acggtgaagc caccgaaaat
    41461 attaatgctg gctataagca ccgcgataaa actaaggaag ctaacccagc cgccctggcc
    41521 aatctgcaac agtgctccga caacaataat ccctgaaatc gcgttggtga ccgacatcaa
    41581 cggtgtatgc agcgcatgcg atacattcca caccacgtaa taaccgacaa cgcaggccag
    41641 cgcgaaaacg gtgaagtgcc caagaaactc tttcggcgca acgcttgcca gccaaccgaa
    41701 aaggatgatt gccagcgcca tcaatgcgta tttacgccac ggtgagcagg cacatttttc
    41761 ctcagttttc acttccggtg ccgctttttg tgccgcctgc ggctgagctg atacctgaat
    41821 cggcggtgcc ggccaggtaa tttcgcccgc acggatcacg gtcacgccgc gaatcaccac
    41881 atcatcaaaa tcaacagtga tattgccgtc tttctctttg cacaacagtt tcagcagatt
    41941 aacgaggtta gtaccgtaaa gctgtgagga ttgcgtcggc agacggcccg gaagatcggt
    42001 ataaccaatc actttgacac cattttccgt agtgaagatt tcacccggca cggtgtattc
    42061 acagttgcca ccgttttggg ctgccaggtc gacaatcaca ctgcccgcct tcatggagtc
    42121 aaccatttca cgggtaatta gcttcggcgc tgttttgcct ggaataagcg cggtggtgac
    42181 aatgatatcg acctcttttg cctgggcggc aaagagttcc atttccgctt tgatgaacgc
    42241 gtccgacatc actttggcat agccatcgcc gctgcccgct tcctctttaa aatccagctc
    42301 gaggaattcc gcgcccatac tttgaacttg ttctttcact tccgggcggg tgtcgaatgc
    42361 acgcacaatc gcgccgagac tgtttgctgc gccaatggcg gccagacctg caacacccgc
    42421 accaatcacc atcacttttg ccggtggcac tttcccggcc gcagtaattt gcccggtaaa
    42481 gaagcgccca aattcatgtg ccgcttcaac aatggcgcga taaccggcga tgttcgccat
    42541 cgagcttagt gcgtccagcg attgtgcgcg tgagatacgc ggcacagaat ccatcgccat
    42601 cacggtcacg ttacgttccg caagtttttg cattaattcc ggattctgcg caggccagat
    42661 aaaactcacc agcgttgtcc caggattcag taacgcaatt tcatcatcta acggcgcatt
    42721 gaccttcaga atgatctctg actgccagac gctattccct tctacaattt cagcgcccgc
    42781 ttgcacaaac gctttatcgt caaaacttgc cagttgaccc gcgccgctct ctaccgcgac
    42841 ggtaaaaccc agtttcagca gctgttccac tgtttttggc gttgctgcaa cacgggtttc
    42901 attggttaac cgttctcttg gtatgccaat tcgcatgata ttcccttcca tcggttttat
    42961 tgatgatggt ttgcctgtgt caggagccac acaagccgct catgtacgag ctaaatgtta
    43021 ctccgttaaa ataaattagt aacaaacgcc ctataacgta ctgaaaatta tgcctgtgat
    43081 ctagcgccaa aaatcagtat ttcggcgtga actcgcaaaa tattaacgat tcagccgtga
    43141 tagtgggata aacaccttag aacgccggat aaagactgat aattgtcttc gacggtcggg
    43201 taaaacgaga catcgccccg gcacgaatca ctacttaaca ttaaattaac ttatataatt
    43261 cagttgcttc agtagtaatg atgctgatac ggctgttttt taagcataga cggtcatttg
    43321 agcaggatta aaattggctt aaagaatgtg atatgaaaaa tgacgcagac agttacaccg
    43381 tttaaatgca ataatcagcc acgtttctcg ttaataacaa taccagtacc tggtttgcgc
    43441 aaggcgaagg attattttta tgaagcttaa gaacaccctc ctggcgtcgg cactgctttc
    43501 tgctacggca ttctccgtta acgcagcaac agaactgaca ccggagcaag cggcagcggt
    43561 taaacctttt gaccgtgtag tggttaccgg tcgttttaat gctattggcg aagcggtgaa
    43621 agccgtttct cgtcgcgcag ataaagaagg tgccgcctct ttttatgttg tcgacacttc
    43681 tgattttggt aacagcggta actggcgtgt ggtcgctgac ctctataaag ccgatgctga
    43741 aaaagcagaa gaaacaagta atcgcgtaat taacggtgtt gtcgaactgc cgaaagatca
    43801 ggctgttctg attgaaccgt ttgacacggt caccgtccag ggcttctatc gtagccagcc
    43861 agaagtcaat gatgccatca ccaaagcggc aaaagcgaaa ggtgcctact ctttctacat
    43921 cgttcgtcaa atcgatgcca accagggcgg caaccagcgt attactgcat tcatctataa
    43981 aaaagatgct aagaaacgta tcgtccagag cccggatgtg atcccggcag attccgaagc
    44041 aggacgtgca gctctggctg ccggtggcga agccgcgaag aaagttgaga tcccaggtgt
    44101 tgcgactacc gcatcaccaa gttctgaagt cggtcgtttc tttgaaaccc agtcatcaaa
    44161 aggcgggcgt tacaccgtca cgctcccgga tggcactaaa gtcgaagaac tgaacaaagc
    44221 gaccgcagcg atgatggtcc cgttcgacag catcaaattc tctggcaact acggcaacat
    44281 gaccgaagtc tcctatcagg ttgcgaaacg tgccgcgaag aaaggtgcta agtattacca
    44341 catcacccgc cagtggcagg aacgtggtaa taacctgacc gtcagcgcag atctgtataa
    44401 ataactattc agttactcct ataaggcggc ttgatgccgc ctttcgcatt tttagtcaca
    44461 aatttccccg cgaccattgc atgcagacac atctcttcgt aaaatcccgc gcttcagtgg
    44521 caaactccat ttttatgcgt tttgccctaa tatttattct tcttatcacg ttttaatcac
    44581 tggatatcga tggaaaagaa actgggactg agcgcactca ccgcgctggt attaagctca
    44641 atgctgggcg cgggtgtttt cagtctgccg caaaatatgg cggcagttgc cagcccggca
    44701 gcactgctca tcggctgggg tattactggc gctggcattt tattgctggc ctttgccatg
    44761 ctgatcctca cgcgcattcg tcccgaactt gacggcggta tctttaccta tgcccgcgaa
    44821 gggtttggcg agctaatcgg cttttgttcc gcatggggat actggctgtg cgcagtcatc
    44881 gccaacgtct cctatctggt gatcgttttt tccgcgttaa gcttttttac ggacacgccg
    44941 gaattgcgcc tgttcggcga tggtaatacc tggcaatcga tagtcggtgc atcggcttta
    45001 ttgtggattg ttcacttttt gatcctgcgc ggggtgcaaa ccgctgccag cattaacctg
    45061 gtggcgacac tggcaaaatt gttgccgctg ggtctgtttg ttgtgctggc gatgatgatg
    45121 ttcaaactgg ataccttcaa gctcgacttc accggacttg cacttggcgt acccgtgtgg
    45181 gaacaggtga aaaacaccat gctgatcacc ctgtgggttt tcattggtgt ggaaggtgcc
    45241 gtggttgttt ctgcgcgtgc gcgtaataaa cgtgatgttg gcaaagcgac actgctggcg
    45301 gttctctccg ctctgggcgt ttacttgctg gtaacgctgc tttcgctggg cgtggtggca
    45361 cgtcctgaac tggctgaaat tcgtaacccg tcaatggccg gtctgatggt ggaaatgatg
    45421 ggaccatggg gcgaaatcat catcgctgcc ggtttgatcg tttccgtttg cggcgcgtac
    45481 ttaagctgga ccatcatggc ggcagaagtt ccgttcctgg ctgccactca taaagcattc
    45541 ccacgcattt ttgcgcgcca gaacgcacaa gctgcgccat ccgcctcgct gtggttgacc
    45601 aacatctgcg tgcaaatttg tctggtactc atctggctga ccggttccga ttacaacacg
    45661 ttgctgacca tcgcctcaga aatgattctg gtgccctatt tcctggtcgg cgcgttcttg
    45721 ctgaaaatcg caacccgtcc actgcataaa gcggtaggtg tcggtgcctg catttatggc
    45781 ttatggttat tgtacgcctc tggtccaatg cacttgctgt tatccgttgt tctgtatgcg
    45841 ccggggctgc tggttttcct gtatgcgcgc aaaacgcata cacatgataa tgtactgaac
    45901 cgtcaggaaa tggtgctgat tggcatgctg ttaattgcct cagttccggc gacctggatg
    45961 ctggtgggat aacgttcatc ccatcgttgg atagcaaagg agataacgat gggtaaagcc
    46021 cagcccttgc caatattaat tactggcgga ggtcgtcgca tcggcctcgc cctcgcctgg
    46081 catttcatta atcaaaagca accggtgatt gtcagctatc ggacgcacta tccagccatt
    46141 gatggactga ttaaggcagg tgcgcagtgt attcaggctg atttttcgac caacgacggt
    46201 gtgatggcgt ttgccgatga agtactaaaa agcacccatg gtctgcgtgc tattttgcat
    46261 aacgccagtg cgtggatggc ggaaaaacca ggtacaccac tggccgacgt actggcttgc
    46321 atgatgcaga tccacgttaa taccccatac ctgctcaacc atgcgctgga aagattactg
    46381 cgtgggcacg gacacgccgc cagcgatatc attcacttta ccgattatgt ggtggagcgc
    46441 ggtagcgaca aacatgttgc gtatgctgca agcaaagcgg cactggataa tatgacccgc
    46501 tcgtttgccc gcaagctggc accggaagtg aaagtgaatt ctattgcgcc atcgctgatc
    46561 ctgtttaatg aacatgatga tgccgaatat cgacaacagg cgctgaataa atcactgatg
    46621 aaaaccgcgc ctggcgagaa agaagtgatc gacctggtcg attacttact taccagctgc
    46681 tttgtcaccg gacgcagttt cccacttgat ggcggtcgtc atctgcgtta atgcagcttt
    46741 atccagcata taatcaacac ccatgcgctt atcccccaac acgcaacaga accaacaaaa
    46801 gcggcgggca agcgcatcat tccggtgaaa taccacagcg acaccaggta aacaaaatag
    46861 ggaataatcg accacatact aaaaatgatg gttgcgcgta aggcttcaat gccgcgttcg
    46921 ctggcaacaa tataatgcgc gataagcgca aaggtcggga aaagtggaat cagcccggcg
    46981 atataataat ttttcgtttt tgctaaaaca ccaatcaaca gcactaccag cgcaccgagc
    47041 gcggctttga ttaccagccc catcttttta ccttaacact tccataacaa gtcatcagta
    47101 gaatacctga tgaaaacttg tttagaaacg attgatagta agtaaaaaca gcgcggtgta
    47161 ttgtgacgtt tttatatcta ccgtgaatgt tatgaacact atcgtatttg tggaagatga
    47221 tgcggaagtc ggttcactga ttgccgcgta cctggcaaaa catgatatgc aggttaccgt
    47281 agaaccgcgc ggcgaccagg ccgaagaaac cattttgcga gaaagtccgg atttggtgtt
    47341 actcgacatc atgctaccag gcaaggacgg catgaccatt tgtcgtgatt tacgcgcaaa
    47401 gtggtctgga ccgattgttc ttctaacctc tctcgatagc gatatgaacc acatcctggc
    47461 actggaaatg ggtgcctgcg actatattct caaaacgacg ccccctgctg ttttgctagc
    47521 gcgtttacgt ttgcatttgc gtcagaatga gcaagccaca ctgaccaaag gtcttcagga
    47581 aacgtctctg actccctaca aagccctgca tttcggcacg ttgaccatcg atcccatcaa
    47641 ccgcgtagtc accctggcta acactgaaat ctcgctctcg acagctgatt tcgaattatt
    47701 gtgggaatta gctacccatg ccgggcaaat catggaccgc gatgcattgc tgaaaaattt
    47761 acgcggcgtc agttatgacg gactggatcg tagcgtggac gtggctattt cgcggttaag
    47821 aaaaaaactg ctcgataacg ccgcagaacc ttatcgcatt aaaactgtgc gtaacaaagg
    47881 ctatcttttt gcgcctcatg catgggaata agcgatgaaa aaactgttta tccagtttta
    47941 cctgttattg tttgtctgct tccttgtgat gtctctgctg gttgggctgg tgtacaaatt
    48001 taccgccgaa cgcgcgggca aacagtcgct ggatgatttg atgaacagtt cgctgtatct
    48061 gatgcgcagc gaattgcgag agatcccccc acacgactgg ggtaagacgc tgaaagagat
    48121 ggatttaaat ctctctttcg atctgcgtgt cgagccactg agtaaatacc atcttgatga
    48181 tatttccatg caccgactgc gtggcggcga aattgtcgcc ctggacgatc agtacacgtt
    48241 tttgcagcgt atcccgcgca gccactacgt gctggcagtt ggtcctgttc cttatcttta
    48301 ttatctccat cagatgcgat tgctggatat cgccctgatc acttttattg ctatttccct
    48361 cgcctttccg gtgtttatct ggatgcgtcc gcactggcag gatatgttaa aactggaagc
    48421 agcggcgcaa cgatttggcg atgggcatct caatgaacgt atccactttg atgagggttc
    48481 gagctttgaa cgacttggta tcgcatttaa ccagatggcg gacaatatca acgccttgat
    48541 tgccagcaaa aaacagctta ttgacggtat cgctcacgaa ctgcgaacac cgttagtgcg
    48601 cctgcgttat cgactggaga tgagcgataa cctgagcgcc gccgaatccc aggcgttgaa
    48661 tcgtgatatc agtcaacttg aagctttaat tgaagagctg ctgacttatg cccgactcga
    48721 tcgcccacaa aacgagcttc atcttagcga accagacctg ccgttgtggc tgtcaacgca
    48781 tctggcagac attcaggcag taacgcccga taaaacggta cggattaaaa cgctcgcgca
    48841 aggccattat gcggcgttgg atatgcgctt aatggagcgc gtgctggata atttgctcaa
    48901 taacgccctg cggtactgcc attcaacggt tgaaaccagc ctgctactgt cggggaatag
    48961 agcgacatta attgttgagg atgatggccc agggattgcc ccagaaaacc gcgaacatat
    49021 ctttgaacct tttgttcgcc tcgatcccag ccgggatcgc tcaaccggcg gctgcgggct
    49081 ggggctggca attgtccact ctatagcact ggcaatgggc ggtacggtta attgtgacac
    49141 cagcgaactg ggtggtgctc gcttctcgtt tagctggccg ttatggcata acatcccgca
    49201 atttacctct gcctgacact acgcgcacga tggtcaagtc accaccactg tgctataaaa
    49261 taagtatgtt gtaactaaag tggttaatat tatggcgcgt tacgatctcg tagaccgact
    49321 caacactacc tttcgccaga tggaacaaga gctggctgca tttgccgctc atcttgagca
    49381 acacaagcta ttggttgccc gcgtgttctc tttgccggag gtaaaaaaag aggatgagca
    49441 taatccgctt aatcgtattg aggtaaaaca acatctcggc aacgacgcgc agtcgctggc
    49501 gttgcgtcat ttccgccatt tatttattca acaacagtcc gaaaatcgca gcagcaaggc
    49561 cgctgtccgt ctgcctggcg tgttgtgtta ccaggtcgat aacctttcgc aagcagcgtt
    49621 ggtcagtcat attcagcaca tcaataaact caagaccacg ttcgagcata tcgtcacggt
    49681 tgaatcagaa ctccccaccg cggcacgttt tgaatgggtg catcgtcatt tgccggggct
    49741 gatcaccctt aatgcttacc gcacgctcac cgttctgcac gaccccgcca ctttacgctt
    49801 tggttgggct aataaacata tcattaagaa tttgcatcgt gatgaagtcc tggcacagct
    49861 ggaaaaaagc ctgaaatcac cacgcagtgt cgcaccgtgg acgcgcgagg agtggcaaag
    49921 aaaactggag cgagagtatc aggatatcgc tgccctgcca cagaacgcga agttaaaaat
    49981 caaacgtccg gtgaaggtgc agccgattgc ccgcgtctgg tacaaaggag atcaaaaaca
    50041 agtgcaacac gcctgcccta caccgctgat tgcactgatt aatcgggata atggtgcggg
    50101 cgtgccagac gttggtgagt tgttaaatta cgatgccgac aatgtgcagc accgttataa
    50161 accacaggcg cagccgcttc gtttgatcat tccacggctg cacctgtatg ttgcagatta
    50221 acgcccggct ttcatactgc cgaccatctg ttctggccgt acccagctgt caaactcggc
    50281 ttcgctaaga taccccagcg caagggccgc agcttttaag gtcagccctt ctttatgcgc
    50341 ttttttggcg atctccgcgg ctttgtcata accaatgtgg gtgttaagcg cagtcaccag
    50401 catcagcgat tcattgagta attgattgat tcgctcacga ttcggttcaa tacccactgc
    50461 gcagtgtttg ttaaaacttt ccatgccatc tgccagcaag cgcaccgatt gcaggaaatt
    50521 atggatcacc atcggacgga agacgttcag ttcaaagtta ccggaagcgc cacccatgtt
    50581 gatcgccacg tcgttcccca ttacctgaca gcagagcatg gttaatgctt cacactgggt
    50641 tgggttcact ttccccggca tgattgagct gcccggctca ttttccggga ttgagatttc
    50701 accaattccg cagcgcgggc cagaggccag ccagcggaca tcattggcga ttttcatcag
    50761 tgacgcagcc aaccctttca acgcgccgtg cgcctgaacc agggcatcac aggtcgcaag
    50821 cgcttcaaat ttgttcggcg cggtaacaaa cggtgcacag gtaatgactg ccagttcatc
    50881 tgctacgcga cgcgcatact ccggatgggt atttagtcca gtacccaccg ctgtaccgcc
    50941 aagagccagt tccgctacgt gaggcaggct gtattcgata tgtttgagat tatgctcgag
    51001 catcgctacc cagccggaaa tctcctgccc tagtgttagc ggcgtggcgt cctgcaagtg
    51061 ggttcgaccg attttgacga tatcggcaaa tgcacgcgat ttttcactca gtgtctgtgt
    51121 cagggtttta agctgcggaa tgagttgctt gcgcagcgcc agcagcgccg caacgtgcat
    51181 cgccgtcgga aagacatcgt tggaactttg gcttttgttc acgtcgtcgt tagggtgaac
    51241 tttacgttcc atcccgcgca cgccgccgag taattcactg gcccggttag ccagcacttc
    51301 gttcatgttc atgttacttt gcgtgccgga gccggtctgc cagatagcca gcgggaattc
    51361 gtcgtcatgc tgtcctgcca gtacttcatc cgccgcctgc cgaatggcgc tcgctttctc
    51421 ttcagacaac aagcctaaat cttcattaac ttttgccgct gcgcgcttgg ttagcgccag
    51481 cgcatgaatc agtgaggtgg gcattttctc cgtcgaaatg cggaaatgct ccagcgagcg
    51541 ttgagtttgt gcgccccaca gcttatctgc cgggacatca atcgccccca tcgaatcttt
    51601 ttcgctgcgt actgtattca tggcctgctc ctcacctgtt taattttttc tttctgtttt
    51661 gctttcgtta agcaactttt agctcactta ttatttacta tttgataaca aatgtttggt
    51721 ctttcgtgcc atgtaaaaaa accgccccga agggcggctc tgtttatttc acacagcgag
    51781 tgcactgtgt gagttgtatc tgctggaaga agtcatttcc tttatcatcc acaaggataa
    51841 acgccgggaa atcttccact tcaattttcc agatggcttc cattcccagt tccggatatt
    51901 caacacattc caggctctta atacttccct gcgccaatac agcggccgga ccaccgatac
    51961 tgccaaggta gaagccgccg tgttttttac aggcatccgt cacctgctgg ctgcggttgc
    52021 ctttcgccag catgatcata cttccgccct gcgcttgcag ttgatcgaca taagaatcca
    52081 tccgtccggc ggtcgttggg ccaagagaac cggaggcata accttccggc gttttggccg
    52141 gacccgcgta gtaaatcgga tgatctttaa tgtactgcgg cagcccttca ccgttatcca
    52201 tccgctcttt cagtttggcg tgagcaatat cacgaccgac gataatcgtg ccgttaagcg
    52261 ataagcgtgt agaaacggga tactgcgaca actgtgcgag gatctctttc atcggacggt
    52321 taaggtcaac gcgcaccgct tcgccttctc ccgctttacg cagctcttca gggatatatt
    52381 tacctggatt atgttccagt ttttcgatcc agatcccctg acggttgatc ttcgctttga
    52441 tattacggtc agcagagcag gaaacaccca taccaaccgg acaggatgcg ccgtgacgtg
    52501 gcaggcgaat cacgcgtatg tcgtgagcga agtatttacc accaaactgc gcacccagac
    52561 cgagattttg cgcttcgatc agcaattctt tttccagttc cacatcgcgg aatgcctgac
    52621 cgtgctcatt cccttccgtt ggcagttcgt catagtattt agcggaagcc agtttcactg
    52681 ttttaaggtt agtttctgca gaagttccac caattacgaa cgcaatatga tacggaggac
    52741 aggccgccgt acccagcgtg cgcatcttct caaccaggta atttttcagt ttccccggcg
    52801 ttagtaacgc tttggtttcc tgatagagat acgtcttgtt tgccgaacca ccacctttgg
    52861 cgatacagag gaatttgtac tcgtcgccat caacggcata aagatcgatc tgcgctggca
    52921 gattggtgcc ggtattcacc tctttataca tatccagcgg cgcgttttgc gagtagcgca
    52981 aattatcttc gatataagtg ttatagacac cgcgcgccag cgccgcttca tcacagccac
    53041 cggtccatac acgctgccct tttttaccaa caataatcgc agtgccggta tcctgacagg
    53101 ttggcagaac acctttcgcc gcgatgtcgg agttgcgcag gaattgcagc gccacatatt
    53161 tatcattttc gctggcttcc gggtcacgca gaatgtcggc cacctgttgt tggtgagccg
    53221 gacgcagcat aaatgacgca tcatgaaatg cctgacgcgc caacagagtt aacgcttcgg
    53281 gtgcgacttt caaaatctcc tgcccttcaa attcagatac gctaacgtgt tcgctggtta
    53341 gcaggtaata ctcagtatca tcttttttga gtggaaaagg agcctgataa tgaaagggtt
    53401 tgtttgacat tgttctctca cttactgcct ggtttggtta tgctctgggc gggtgttccg
    53461 ttgccctgtt aaaagcgagt aacaatatcc tacacacttt tttaacaaaa actgagacta
    53521 gtacgacttt ttgcggctcc aggttacttc ccgtaggatt cttgctttaa tagcgggatt
    53581 aatttccaca ttaaaacagg gattgatcat gcaaaaactc attaactcag tgcaaaacta
    53641 tgcctggggc agcaaaacgg cgttgactga actttatggt atggaaaatc cgtccagcca
    53701 gccgatggcc gagctgtgga tgggcgcaca tccgaaaagc agttcacggg tgcagaatgc
    53761 cgccggagat atcgtttcac tgcgtgatgt gattgagagt aataaatcga ctctgctcgg
    53821 agaggccgtt gccaaacgct ttggcgaact gcctttcctg ttcaaagtat tatgcgcagc
    53881 acagccgctc tccattcagg ttcatccaaa caaacgcaat tctgaaatcg gttttgccaa
    53941 agaaaatgcc gcaggtatcc cgatggatgc cgccgagcgt aactataaag atcctaacca
    54001 caagccggag ctggtttttg cgctgacgcc tttccttgcg atgaacgcgt ttcgtgagtt
    54061 ttccgagatt gtctccctac tccagccagt cgcaggtgca catccggcaa ttgctcactt
    54121 tttacaacag cctaatgccg aacgtttaag cgaactgttc gccagcctgt tgaatatgca
    54181 gggtgaagaa aaatcccgcg cgctggcgat tttaaaatcg gcgctagaca gtcagcaggg
    54241 tgaaccgtgg caaacgattc gtttaatttc tgaattttac ccggaagaca gcggcctgtt
    54301 ctccccgctg ttactgaatg tggtgaaatt gaatcctggc gaagcgatgt tcctgttcgc
    54361 tgaaacaccg cacgcttacc tgcaaggcgt ggcgctggaa gtgatggcga actccgataa
    54421 cgtgctgcgt gcgggtctga cgcctaagta cattgatatt ccggaactgg ttgccaatgt
    54481 gaaattcgaa gccaaaccgg ctaaccagtt gttgacccag ccggtgaaac aaggtgcaga
    54541 actggacttc ccgattccag tggatgattt tgccttctcg ctgcatgacc ttagtgataa
    54601 agaaaccacc attagccagc agagtgccgc cattttgttc tgcgtcgaag gcgatgcaac
    54661 gttgtggaaa ggttctcagc agttacagct taaaccgggt gaatcagcgt ttattgccgc
    54721 caacgaatca ccggtgactg tcaaaggcca cggccgttta gcgcgtgttt acaacaagct
    54781 gtaagagctt actgaaaaaa ttaacatctc ttgctaagct tattaaaggc ttataacacc
    54841 ttcaggcggc cagtccgcct gatttcattt tatggataat cattatgaat aaatcgctgg
    54901 tagcggtagg cgtcattgtt gcgctaggcg tagtctggac aggcggcgca tggtatacag
    54961 gcaagaagat tgaaacccat ctcgaagaca tggtcgcgca ggcgaacgcg caactcaaac
    55021 tgacagctcc tgaatccaac ctggaagtga gttatcaaaa ctatcatcgc ggcgtattca
    55081 gcagccagtt gcaactgttg gtgaaaccca ttgccgggaa agaaaatccg tggattaaaa
    55141 gcggtcagag cgtcatcttc aacgaatcgg ttgatcatgg tcccttcccg cttgcccagc
    55201 ttaaaaaact gaacctgatc ccgtcgatgg catcaattca aaccacgctg gttaataacg
    55261 aagtaagcaa accactgttt gatatggcaa aaggtgaaac gccttttgag attaactcgc
    55321 gcattggtta cagcggtgat tccagttccg atatttcgct caagccactg aattacgagc
    55381 aaaaggatga aaaagtcgcc tttagcggcg gcgagttcca gttaaatgct gacagagacg
    55441 gcaaagccat ctccctttcc ggggaggcgc aaagtggtcg gatagacgca gttaacgaat
    55501 acaaccagaa agtgcagttg acctttaata atctgaaaac cgacggttcc agcacgctgg
    55561 caagttttgg tgagcgcgta ggaaaccaaa aactgtcact ggaaaaaatg accatttcag
    55621 tggaaggcaa agaactggca ctgctggaaa gcatggagat caacggtaaa tcggatctgg
    55681 tcaatgacgg taaaacgatc aatagccaac tggattactc gctaaacagc ctgaaggtac
    55741 agaatcagga tctgggcagc ggcaagctga ctttaaaagt cggccagatt gatggtgaag
    55801 cctggcatca gtttagccag caatataacg cgcaaactca ggcgctgctg gcacagccag
    55861 aaattgccaa caatcccgaa ctttatcagg agaaagtgac ggaagccttc tttagcgccc
    55921 tgccgctgat gttgaaaggc gatccggtga ttactatcgc gccgctaagc tggaaaaaca
    55981 gtcagggtga aagtgcgctg aatctgtcgc tgttcctgaa agatccggca acgactaaag
    56041 aagcgccgca aacgctggcg caggaagtag atcgttcggt taaatctctg gatgcgaaac
    56101 tgaccattcc ggtggatatg gcaactgagt ttatgactca ggtagcgaag ctggaaggtt
    56161 atcaggaaga tcaagcgaaa aaactggcga aacagcaagt tgaaggtgca tcagcaatgg
    56221 ggcagatgtt ccgtctgacc accttgcagg acaataccat caccaccagc ctgcaatata
    56281 ctaacggtca gataacgtta aacgggcaga aaatgccact ggaagatttc gttggtatgt
    56341 ttgcaatgct ggcattaaat gttccggtcg tacccgctat tccgcagcag taattcacag
    56401 ccaaaacgcc ggagattttt ctctccggcg ttatttttta cttcagcata aagtcatact
    56461 gaatactcat tttcacatcc cagtaattca ggcgatcgcc cagcgtactg ccatcgcgct
    56521 tttcccgccc tttatcggca gcaagaaaga aattcatccc ttgtaacggc ccttcgctga
    56581 cccgatagtt cataccacct aagatacccg cgccttcaat ccgcacatct cgtttactgg
    56641 attcatagcc gcgagtcaca atcggtgcaa atatcagtgt aaattgcggc gttaaacgat
    56701 agttgacgcc caattgccag gactgcattc cttcacggtt acgatcaaga cttaatgaaa
    56761 agggatagcc aatgtcggta tccaccacgg caccattcat tgcatggcgc aaataaccac
    56821 cactgccaaa tacgcttccc cacggcgcat tccaggtcaa ttgtccacta accaacgccg
    56881 tttcattggg ctggctggta ttacgactta aaccttcgag ctgcgcgtaa aagccgagca
    56941 actccccttt caacgtataa ttcgggtcga gcggtatgct tttctcgaga atactttgta
    57001 tctgattgga aacatctttc tgtaccgatg cccccagaga atagcgactg gtatcatcat
    57061 gccaactggc ggctaaaaaa gaacgtgcgc gatgtttatc gtattttccc gtctggctgt
    57121 tatacacccc ttcatcacga ataccggttg ttgaatcagt ccataaaaat actcgtgaac
    57181 gccacattcc ccacagatca atatttggtg ttaaagccca ataacctaat gctccttcag
    57241 aaactgtcgg taatgtacgt tgcgaactgc cagccattaa cggaatacga taaggtaagc
    57301 taccataact ataatccgtc ccgaagcgac ctaatttaag caggctattt tcactgggtt
    57361 ttatttttac tgcccccagg gcaaagccaa aacttttatc accatcaaga taccaccggg
    57421 tactcatatc agcacgagca cctaatttat aaacataata cgccccgcct tcaacgccaa
    57481 taatattgga ataataacca ctattgaaat cgagcaatcc tccctgtacc catgcgtaaa
    57541 tatctcttcc cgcgccagca ctgggcttat ccgccctgcg caattcgttt ttcagtctga
    57601 tgcgtagtcc cgcttcatcg tcagccagtt gcgccgcata agcagaggta aggccagagg
    57661 cagccgtcag gcaaataacg gccatggcca ctatttttct catagttgca cctttgatgt
    57721 tctgattatt tttattgaat attaattagt gatatcgctg attaattgct gctgcacttt
    57781 tttacgatta tcaatttcaa ccacgatttc tttgaatttt ttatccgtga gcggataaaa
    57841 ccagataata acgaatgcca gtagcataaa tccgcaaggt actaaggcaa ttgatgtgcg
    57901 gatgcccata ataacttccg gcgtttgcac ctgattggcg atatatccgc ttaatcccaa
    57961 aataaaggca ggaattgaac ctccgattgc ctgaccgcat ttacgggtaa atgagaatag
    58021 tgaataggtg agcccttcaa ttcgcacgcc ggtcaggtat tcaccgtatt ctacggtatc
    58081 agcttccagt gcccacatca cagtcatagt aacgccctga ccaattgaag cgatggccaa
    58141 cgcaaccaac gccaccggca gtgaccagac ggaaacccag aagaatagca gataaccgca
    58201 ggttcccagc aaagcgccaa tcaggaaggt attcttttta ccgatcctcg cgaccatccc
    58261 cggcaccagc ggtgccgatg ccacagtacc aaccaggttt tgcaccagta ccagcacagt
    58321 gaacagcccg gtatcattta acacatagcg cacgtagaac aacgacgagg cgctgaccgc
    58381 gaaggtcgaa atcagcacac acagcgcacc gatgcacaac ataaacagcg ggcgattccg
    58441 tttcagggtt tgcagactga tcttcaatga cggttgcgcc acgatacgta ccacattctc
    58501 acgcgtcgat ttgaagcaga tgaagtaaag caccattccg gcaatcgcca gcacaatcgt
    58561 ccagaaatgg tataccgaca ccatctcttc cgggctggag ttcttaatgc tcggtcctat
    58621 cagaaatgcc aggcagacaa aggttaatga agcggcaatc ccgcgagccg cgcccagacg
    58681 ggcgcgggat tgtggttgtt gggtcatcgc ggtagcaaat gaaccataag gaatattcac
    58741 caggctgtag caaagcccga ggcccatgta ggtcaaatat gcatacacta ctttgctgct
    58801 atggctccag tcggtcggta cccagaatac cagcacgctg aagatcatta acggcgcagt
    58861 accgaagagt aaaaacgggc ggaattttcc ccagcgggta ttcacactgt ccaccactcg
    58921 tccggcaaag acgtcggcga aggcatcgaa tacccgcacc agtaacagca tggtgcccgc
    58981 cgcagcggca ccgacgccag cgacgtcggt gtagtaactc aacaggaaga gcgcccccat
    59041 tgcgaaggcg aagttattgg cgacgtcacc gaggctgtag ccgacgatgg tgcgccagga
    59101 gagttgttga ttcattgttt gcctccctgc tgcggttttt caccgaagtt catgccagtc
    59161 cagcgttttt gcagcagaaa agccgccgac ttcggtttgc ggtcgcgagt gaagatccct
    59221 ttcttgttac ctccaacgcg caatatgcct tgcgaggtcg caaaatcggc gaaattccat
    59281 acctgttcac cgacgacggc gctgacgcga tcaaagacgc ggtgatacat atccagccat
    59341 gcacactgat actcttcact ccacatgtcg gtgtacattg agtgcagccc ggctaacgta
    59401 tccacgccgt attcggtgat gataatcggc tgatgcagtt tctcctgcca ggccagaagt
    59461 tctttttcca gtaccttctc tgccgtttcc aaatcgccgc tttggacata ccatccgtaa
    59521 taacggttca ggcacagcac atcaaagaga tcgctgatgg tatcggtgtg agcgtcgcag
    59581 aacattacat tgacgcaggt gatcggacgc gtcgggtcga gtttacgcgt tgcttccgcc
    59641 agtggcgcga aatattcccg tgcaccttgc ggacgggtat ccggttcgtt ggcaatactc
    59701 cacatcacca cgcttgggtg gtttttgtca cgcgctatca gctctttaat cgcctgtaag
    59761 tgcgcttgct gagtttcccc gttgactgcc tcttcgctgt acagttcttt cggcttgttg
    59821 cccgcttcga aaccaatgcc taaagagagg ttaaagccga cagcagcagt ttcatcaatc
    59881 accacgatgc catgttcatc tgcccagtcg agcatctctt cagcgtaagg gtaatgcgag
    59941 gtacggtagg agttggcccc aatccagtcc attaatgcgt ggtcgtgcac catcagcacg
    60001 ttatcgaatc ctttgccacg caagtccgca tcttcatgac gaccaaagcc agtaaagtag
    60061 aacggtttgt ggttaatcag gaactgttcg cccttcactg ccactgaccg gatgccgacg
    60121 cgaagcgggt agatatcaca ctctgtctgg cttttggctg tgacgcacag ttcatagaga
    60181 taaccttcac ccggttgcca gaggtgggga ttcaccactt gcaaagtccc gctggtacct
    60241 tgtccagttg caaccacctg ctgatccgca tcacgcagtt caacgctgac atcaccattt
    60301 gctaccacct gccagtcaac agacgcgtgg ttacagtctt gcgcaacatg cgtcaccacg
    60361 gtgatatcgt ccacccaggt gttcggcgtg gtgtagacca ttacgctgcg atggatcccg
    60421 gcatagttaa agaaatcatg gaagtaagac tgctttttct tgccgttttc atcggtaatc
    60481 accattcccg gcgggatagt ctgccagttc agttcgttgt tcacacaaac ggtgatacgt
    60541 acacttttcc cggcaataac atacggcgtg acatcggctt caaatggcgt atagccgccc
    60601 tgatgctcca tcacttcctg attattgacc cacactttgc cgtaatgagt gaccgcatcg
    60661 aaacgcagca cgatacgctg gcctgcccaa cctttcggta taaagacttc gcgctgatac
    60721 cagacgttgc ccacataatt acgaatatct gcatcggcga actgatcgtt aaaactgcct
    60781 ggcacagcaa ttgcccggct ttcttgtaac gcgctttccc accaacgctg atcaattcca
    60841 cagttttcgc gatccagact gaatgcccac aggccgtcga gttttttgat ttcacgggtt
    60901 ggggtttcta caggacgtaa cataagggac tcctcattca aataaaaata ctggtcaacc
    60961 tttaatctga ttagttaacc aattctgtgt tgcacacagt tatctgtgag aaacccatgg
    61021 aagagaaatg gaaataaaaa gaactgacac cgcgatcaaa aaaccaaaat ctgcaatacc
    61081 cacagcgtga tattgatcgc attaatcttt aaaacagcgt tgacagaagc cataaaataa
    61141 gcaatcgaac gttcgttcga gcatcttgag aacgataaac tctcatgaca tatggctacg
    61201 gtgaatattt ttggggggaa ttctccgatc ccggctagat tgtattttgt acagggaaat
    61261 taaagtatga aacgcgggca cagttatcac cagcccgcga aatgagagga tcaggatgcg
    61321 gttaagatac cgccaatcat cgcgcgtaat ccctgagcaa acgacgcttc acgcgccagg
    61381 tcttccgctt cgatatcggc cagtacaccg taggtcagat ccagcagtaa acgtgaagtc
    61441 attgacgtgt tgatgtctgg gcttatctcg cctttttgct gggcatcacg catccgctgg
    61501 gcaacaaatt cagtgatcgt catatgctta tttttaagca tggcggcgac ctgtgggtta
    61561 cgcatccctt ccgccataat ttcgaccacc agcgcccgtt gcccaaaggc ttcatgggtg
    61621 agagagacaa tagactcgac catatagtca acaaaatgaa tcccttcaat cggttcccgg
    61681 aaacgggcca gcgccctctc ctggtcctgt aagataatcg cctgaatcaa ggcttctttg
    61741 gagatgaaat ggtgatagag cgtcccggga ctaatggcgc aggatttaca gatggctttc
    61801 atcgaggcac tgtgaaatcc attttctgaa aaaatctctc tggcagcatt gaggatccgg
    61861 gtccgtgtcg gttgtgcttc agtctgcatg ttatccatca ttaaaccatt atagttagcg
    61921 tgaataacta gtttaccgcg ttgtcaggtg agcgcctatc attgctgttg aatagtgcga
    61981 aggcacactc tattcgtatg cttttcatcc agctattggt taaccaatag ccgtgatttg
    62041 gctgccagtt gtttagcaga gacgttgatg aattgcacac gctatcccgg taaacaacac
    62101 atacggctgt ttaccggttc gttagtgtat taattgagct cctgtacccc accaccggag
    62161 acggtgagaa tttgtccgct tacccagctg gctgcaggcg agcaaaggaa cagcgccgcg
    62221 ttagcaatat cttgcggttg gcccagacgt ctgatcggcg tgtgctgtaa cattttttgt
    62281 tcaatttctg gtgtaataac ggatttcagg gcatcggtta atattgcccc cggcgcaatg
    62341 ccattcaccc gaatattttt ttcacccagg tcaaatgcca tatttctgac cagatgactg
    62401 gccgcagctt tagatgatgc ataggaagtc atgtttatat ttttattttc tgccgccata
    62461 gaagtgatgg tcagaataac gccaccgcca tttttttcca tttctggcgc aacaagttgt
    62521 gacagatgga aaaaagaaaa cacattcagt tcataagcac ggcgaaaatc tgccattggc
    62581 atatcaaacg gtttaggacc accgccaccg gcgttgttaa ccaggatatc aactttaccc
    62641 agcttactga cggcaaagtc tgccagtgca gagagttcct gttcggaagt aatatcacaa
    62701 cggcaggcaa atgcctgacc acccagttgt tgaatttcgt ctacaacatg gttagctgcg
    62761 tcggcgttaa tatcactgac caccacagat gcgccagctg tcgcgaatgt aatggcgatt
    62821 tctttaccaa tacctgcacc cgcacctgtg atgatggcgc attttccgtc gagtctcagg
    62881 ttgtcagaat taaacacata aacctcctgt gaacttcagt aaaaataaaa ggcaccgcct
    62941 gtgtgctaca ttttttatca ttaaccttga ggaaaggaca ctaccaggta tagcagataa
    63001 agagaggatt atttcgccgc aatgagccgg gcgggaataa taagattgcg tgaatgcgtc
    63061 tcttcatggg tgattttttg catcatgcga tccgcaagtg tggtaccaag ttcccgcgca
    63121 ggcgtgctgg cccaggtaac gggtatatca tcaagtgtgg ttggtgtcgc atcggtaaat
    63181 gccgccagcg aaacttgttg ctcaaagtaa cgatcgactc cgctttcccc gctttgccgc
    63241 cctgctttga gcaaaccaaa ccatgccccc atcgcaatag tttcgttata gcaaaccaca
    63301 gcactgatgg tcgggttatg acgtaaaagc gccgtgatag cttccgcggc ttgcttctgg
    63361 ctggatgtgc actccagcac ccaatcgctg tgaaacggca ggccaaattt tagtagagtt
    63421 gcacaatagc cccccacccg ttctgcacgg gttaatgagg aactttgccc tcccagccag
    63481 gcgatccgct gatgcccatt gcgaatgaga tgctccgtca acaactgtgc agcctgcatg
    63541 ttgtccgggc gaaccgtatc aacatcatca agataactgg cacgggaagc gaaaatcacc
    63601 gggatagctt tttcttctgc catccgtcgc aggtcatcgc tgcttcctgc agccccggca
    63661 attaccacac catccacacc ctgattcagt aacagtgaaa accgctgtgc cagctgctcg
    63721 ccgtctttac cgccgtgaag caaaaaaacc atccgtccct gcgcttccag agcttccgtc
    63781 aatccggccg tcaattcggc gtaaaacggc gcagataaat cacggacgat caaaccaatg
    63841 acgccgcttt gcccgccgcg cagcgccgac gcctggcgat tgcgcacaaa tcccagctct
    63901 tcaatggcgg cgttaacgcg ttctcctgtg gcggtagaga ttcgcccttt gccactaagc
    63961 accagcgaaa cggtacttac cgacacgccc gcagccagcg caacatcatg aatggttatt
    64021 tttttggcgg tagccatgca gatgacctac tccctgatta tgtgacagat aaaacgtttt
    64081 accttttatt tatcttatac ccgctattat cgttgcgtaa tgtgatttat gcctcactaa
    64141 aatttgataa aacgttttat cttctcgcgc aatttactga atccagattg ttctctacga
    64201 ggagtcgttt tatgacggcg aaaacagcac cgaaagtcac gctgtgggag ttcttccagc
    64261 agttaggcaa aaccttcatg ttacccgtgg cattattgtc gttctgcggc attatgctcg
    64321 gcattggtag ttctcttagc agccatgatg tcataaccct gatcccggtc ctgggcaacc
    64381 ccgtgttgca ggctatcttt acctggatga gtaagattgg ctcgtttgct tttagtttcc
    64441 tgcctgtcat gttctgtatc gccatcccgc tgggcctggc acgcgaaaat aaaggcgtag
    64501 cggcattcgc tggcttcgtc ggttatgcgg taatgaacct cgcggtaaac ttctggttga
    64561 ccaataaagg cattctgcca accacggatg ccgcggttct gaaagccaat aacatccaga
    64621 gcattcttgg gatccagtcg atcgataccg ggatcctcgg tgcggtgatc gccggtatta
    64681 tcgtctggat gctgcatgag cgtttccata atatccgcct gccggatgcg ctggcattct
    64741 tcggcggtac gcgcttcgta ccaattatct cctcgctggt gatgggcctt gtcggcctgg
    64801 tgattccatt agtctggccg attttcgcca tgggtattag cggcttgggc catatgataa
    64861 acagcgcggg tgatttcgga ccgatgctgt ttggtaccgg tgaacgtctg ctgttgccgt
    64921 ttggtctgca tcacattctg gtagcattaa ttcgctttac cgacgcaggc ggcacgcagg
    64981 aagtctgcgg tcaaaccgtc agcggcgcac tgaccatctt ccaggcgcaa ttgagttgcc
    65041 cgaccactca cggtttttct gaaagcgcca cgcgtttcct ttcgcaaggt aaaatgcctg
    65101 cgtttctcgg cggtctgccg ggtgcagcgt tagctatgta tcactgcgcg cgcccggaaa
    65161 atcgccataa aattaaaggt ctgctgattt ctggcctgat cgcctgcgtc gttggcggca
    65221 ctaccgaacc gctggaattc ctgttcctgt tcgtagcgcc agttctgtat gtcatccacg
    65281 cgctgttaac cggcctcggc ttcaccgtca tgtctgtgct gggcgtcacc atcggtaata
    65341 ccgacggcaa tatcatcgac ttcgtggtgt tcggtatttt gcatggtctg tcaaccaagt
    65401 ggtacatggt gccagtggtg gcggcaatct ggtttgtcgt ttactacgtc atcttccgtt
    65461 tcgctatcac ccgcttcaat ctgaaaaccc cggggcgcga tagcgaagtt gccagctcaa
    65521 tcgaaaaagc cgttgccggt gcgccgggta aatcaggtta caacgttcct gcaatcctcg
    65581 aagcattagg cggtgccgac aatattgtca gcctcgataa ctgcattacc cgtctgcgtt
    65641 tgtctgtgaa agatatgtcg cttgttaatg tgcaggcact gaaggacaat cgggcaattg
    65701 gcgtagtaca acttaatcaa cataacctgc aggttgttat cgggccacaa gttcagtcag
    65761 taaaagatga aatggccggt ctgatgcata ctgtccaggc ataaggataa gatatgttcg
    65821 atttttcaaa ggtcgtggat cgtcatggca catggtgtac acagtgggat tatgtcgctg
    65881 accgtttcgg cactgctgac ctgttaccgt tcacgatttc agacatggat tttgccactg
    65941 ccccctgcat tatcgaggcg ctgaatcagc gcctgatgca cggcgtattt ggctacagcc
    66001 gctggaaaaa cgatgagttt ctcgcggcta ttgcccactg gttttccacc cagcattaca
    66061 ccgcaattga tacgcagacg gtggtgtatg gcccttctgt catctatatg gtttcagaac
    66121 tgattcgtca gtggtctgaa acaggtgaag gcgtggtgat ccacacgccc gcctatgacg
    66181 cattttacaa ggccattgaa ggtaaccagc gcacagtaat gcccgttgct ttagagaagc
    66241 aggctgacga ctggttttgc gatatgggca agctggaagc cgtgttggcg aaaccagaat
    66301 gtaaaattat gctcctgtgt agcccacaga atcctaccgg gaaagtgtgg acgtgcgatg
    66361 agctggagat catggctgac ctgtgcgagc gtcatggtgt gcgggttatt tccgatgaaa
    66421 tccatatgga tatggtctgg ggcgagcagc cgcatattcc ctggagtaat gtggcgcggg
    66481 gagactgggc gttgctgacg tcgggctcga aaagtttcaa tattcccgcg ctgaccggtg
    66541 cttacgggat tatagaaaat agcagcagcc gtgatgccta tttatcggca ctgaaaggac
    66601 gtgatgggct ttcttcccct tcggtactgg cgttaactgc ccatatcgcc gcctatcagc
    66661 aaggtgcacc gtggctggat gccttacgcg tctatctgaa agataacctg acgtatatct
    66721 cagataaaat gaacgccgcg tttcctgaac tcaactggca gatcccgcaa tccacttatc
    66781 tggcctggct tgatctacgt ccgttgaata ttgacgacaa cgcgttgcaa aaagcgctta
    66841 tcgagcaaga aaaagtcgcg atcatgccgg ggtataccta tggtgaagaa ggtcgtggtt
    66901 ttgtccgtct caatgccggc tgcccacgtt cgaaactgga aaaaggtgtg gctggattaa
    66961 taaacgccat ccgcgctgtt cgctaacccc aattgcgcaa cgtaaaaaat cgttgcgcaa
    67021 tcgtggattt ttaccctgct ttgtttttat aatggtgcgc acttttatat tcagaaaaag
    67081 agtgcgacca tgattgatac caccctgcca ttaactgata tccatcgcca ccttgatggc
    67141 aacattcgtc cccagaccat tcttgaactt ggccgccagt ataatatctc gcttcctgca
    67201 caatccctgg aaacactgat tccccacgtt caggtcattg ccaacgaacc cgatctggtg
    67261 agctttctga ccaaacttga ctggggcgtt aaagttctcg cctctcttga tgcctgtcgc
    67321 cgcgtggcat ttgaaaacat tgaagatgca gcccgtcacg gcctgcacta tgtcgagctg
    67381 cgtttttcac caggctacat ggcaatggca catcagctgc ctgtagcggg tgttgtcgaa
    67441 gcggtgatcg atggcgtacg tgaaggttgc cgcacctttg gtgtgcaggc gaagcttatc
    67501 ggcattatga gccggacctt cggcgaagcc gcctgtcagc aagagctgga ggccttttta
    67561 gcccaccgtg accagattac cgcacttgat ttagccggtg atgaacttgg tttcccggga
    67621 agtctgttcc tttctcactt caaccgcgcg cgtgatgcgg gctggcatat taccgtccat
    67681 gcaggcgaag ctgccgggcc ggaaagcatc tggcaggcga ttcgtgaact gggtgcggag
    67741 cgtattggac atggcgtaaa agccattgaa gatcgggcgc tgatggattt tctcgccgag
    67801 caacaaattg gtattgaatc ctgtctgacc tccaatattc agaccagcac cgtagcagag
    67861 ctggctgcac atccgctgaa aacgttcctt gagcatggca ttcgtgccag cattaacact
    67921 gacgatcccg gcgtacaggg agtggatatc attcacgaat ataccgttgc cgcgccagct
    67981 gctgggttat cccgcgagca aatccgccag gcacagatta atggtctgga aatggctttc
    68041 ctcagcgctg aggaaaaacg cgcactgcga gaaaaagtcg ccgcgaagta acaaaatgga
    68101 tggtgcaaat tgcaccatcc atttttcatg caaggcacaa agtcgcgcga tgtttggcgg
    68161 attcgatgcc cagctcaatc aactccatta cctggattgc ctggcttgcc ggaaccggat
    68221 tttcaccatc gccatttaac gcatcacgaa tagccgcata gtaagccgga taattcccag
    68281 gcaccgtcaa cagcgtttct tcgacacgtt cctcaccttc cacgcgggta agtacgccat
    68341 cacgcatatc gtagccccag tcttcctgcg gtagacgctc gccatttttc agacgttctt
    68401 cctgtggatc gaggccatat ttcacataac tgcctcggga tccatgcacg atataccgtg
    68461 ctgactcagc ggctgccagc atggtaccgt gtaaaatgac tcgccgctgt ggataggaca
    68521 agatggcgtg gaaataatcg gtcgactgcg ctccgggccg taactgtgcc aaatctaccg
    68581 tcatgctgac cggtaaacca aaaagcgtaa tggcctgatc aagaagatgt ggtgctaaat
    68641 cgtaccagat accgctgcct gggccgccct gttcacgcca acgatcgcgc acctgcggac
    68701 ggaagcggtc aaaatgagac tcaaagtaag caacttcacc cagcacgcct tccgcgagta
    68761 aaccttttag cgtcaagaaa tcgctatccc agcgacggtt atggaataca gacagcacac
    68821 gccccaggct ttttgccagc gcatccagct ctcgcgcttg tgacagtgtc acggtaaagg
    68881 gtttatcaac gaccacatgt ttacccgcct caagcgccgc tttggctaac gggaaatggg
    68941 tatcgttggg tgtaggaatg acaatcaggt ctatgttggg atcgttaaac agatgcttcg
    69001 gctcagagac aaccgtaacc gttggccagt cggcttttac ttttgtttca tcactgctgg
    69061 agattaccgc cagttccagc ccgggcgtgc ccgcaatcag gggcgcatgg aaggttttga
    69121 tcgcataacc atacccaatc aacccaacac ggatgttgtc gctcatgtca ttgcctctca
    69181 ttgaagtatg atggctattt gacactatcc tttacccacg ctcaacagtt taataacctg
    69241 ccagcaataa gggatgttgt ttaacttaag tcaaaaaaat agcgaatttt ccaacgacaa
    69301 aagctaaata tcgcaaaaac ctcagtaaaa atcttgctgg agctattatt gctaagtaac
    69361 atttaccccc tgaagttaat ggatcaatca agagagatgt gggctgtaat gaatcgtctt
    69421 attgaattaa caggttggat cgttcttgtc gtttcagtca ttcttcttgg cgtggcgagt
    69481 cacattgaca actatcagcc acctgaacag agtgcttcgg tacaacacaa gtaagctctg
    69541 cacttgtgga gcgacatgct gcccgtccgg gtgcatgttt tcacttgtcg gatattaaac
    69601 caggaattta ttatcttgtt cgatgttgtt ggtgattgtc agggatagta aagcgcgtta
    69661 ctcttttcag agcagttttt catccctgaa tatttgccat cagcgcattc ttattattgt
    69721 aataacacaa gcgttcactt ttggtgaaat tttatcatca ctaataatac ctaccccttt
    69781 ggtattaatt attttatgga ccttttatga ctgttcagga ctacttatta aaatttcgca
    69841 aaatcagttc actcgaaagt ctggaaaaac tctacgacca tcttaattac accctgacgg
    69901 acgatcagga actgatcaat atgtatcgtg ctgccgatca ccgtcgcgca gagctggttt
    69961 ctggcgggcg tttgtttgac ctcggccagg taccgaagtc cgtctggcac tatgtccaat
    70021 aaagaaagta gcgatcggtt ataaaagcct tataataacg cccctaaaat tagatttgcc
    70081 tgtttgcgtc gctattctgg agaacctatg accaccacaa cgccacaacg tattggaggc
    70141 tggttgcttg gcccgttggc ctggctttta gtcgctctgt tgagtacgac gctggcgttg
    70201 ttgctgtata ccgctgcgtt atcttctccg caaacatttc aaacgctcgg cggacaagca
    70261 ctgacgacac aaatcttatg gggcgtttct tttattaccg ctatcgccat gtggtattac
    70321 acactgtggt tgaccatcgc tttctttaaa cgtcggcgtt gtgttcctaa acactatatt
    70381 atctggctgc ttatttccgt attgctggca gtaaaagcat tcgctttttc acccgtggaa
    70441 gatggcatag ccgttcgcca gttgctgttt actttgttgg caaccgcatt gatcgtcccc
    70501 tatttcaaac gctcgtcgcg ggtaaaagcg acgtttgtga atccgtaata accttacagt
    70561 taacctgttg tcgcctgctc tggattaacg gataataggc ggctttttta tttcaggccg
    70621 aaaaatgact gactacctgt tactgtttgt cggaactgta ctggtcaata actttgtact
    70681 ggtcaagttt ctcggtctct gtccgtttat gggggtttcc aaaaaactgg aaaccgcgat
    70741 gggcatgggg ctggcaacaa cgtttgtgat gacgctggcg tctatttgcg cctggcttat
    70801 cgatacgtgg attttgatcc cacttaatct gatttacctg cgcaccctgg catttattct
    70861 ggtgattgct gtggtcgtgc agttcaccga gatggtggtg cgcaaaacca gcccggtgct
    70921 ttaccgtctg ctggggattt ttttgccgct tatcaccacc aactgtgcag tgctcggcgt
    70981 ggcgttgctg aatatcaatc tcgggcacaa tttcttgcag tcggcgctgt acggtttttc
    71041 cgccgctgtc ggtttctcgc tggtgatggt gctcttcgcc gccatccgcg aacgccttgc
    71101 tgtggctgat gtcccggcac cttttcgcgg taatgccatt gcgttaatta ccgcaggtct
    71161 tatgtctctg gcctttatgg gctttagtgg tttggtgaag ttgtaatgaa tgctatctgg
    71221 attgccgttg ccgccgtgag cctgctgggc ctggcgtttg gcgccattct gggttatgcc
    71281 tcccgccgtt ttgcggtgga agacgatccg gtcgttgaga aaattgacga aatcttaccg
    71341 cagagccagt gtggtcagtg cggttatccc ggctgtcgcc cctacgcgga agccatcagc
    71401 tgtaacggtg aaaaaatcaa ccgttgcgcc ccaggtggcg aagctgtgat gctaaaaatt
    71461 gccgagttgc ttaatgtcga gccgcagccg ctggatggcg aagcgcaaga gctaacgcct
    71521 gcgcggatgg tggcggttat tgatgaaaat aactgtattg gctgcactaa atgtattcag
    71581 gcttgtccgg tagacgccat cgttggcgct acccgtgcca tgcatacggt aatgagtgat
    71641 ctctgtacgg gctgcaattt atgtgttgat ccgtgcccga cgcactgcat ctcgttgcaa
    71701 ccggtcgcag aaacacctga ctcctggaaa tgggatctga acaccattcc cgtgcgtatc
    71761 attcccgtgg aacaccatgc ttaagttatt ctctgcattc agaaaaaata aaatctggga
    71821 tttcaacggc ggcatccatc caccggagat gaaaacccag tccaacggta cacccctgcg
    71881 ccaggtacca ctggcgcagc gttttgttat tccactgaaa cagcatattg gcgctgaagg
    71941 tgagttgtgc gttagcgtcg gcgataaagt attgcgcggc cagccgctta cccgtggtcg
    72001 cggcaaaatg ctgcctgttc acgcgcccac ctcgggtacc gttacggcta ttgcgcccca
    72061 ctctacggct catccttcag ctttagctga attaagcgtg attattgatg ccgatggtga
    72121 agactgctgg atcccgcgcg acggctgggc cgattatcgc actcgcagtc gcgaagagtt
    72181 aatcgagcgc atacatcagt ttggtgtagc cgggctgggc ggtgcaggat tcccgacagg
    72241 cgttaaattg cagggtggcg gagataagat tgaaacgttg attatcaacg cggctgagtg
    72301 cgagccgtac attaccgccg atgaccgttt gatgcaggat tgcgcggctc aggtcgtaga
    72361 gggtattcgc attcttgcgc atattctgca gccacgcgaa attcttatcg gcattgaaga
    72421 taacaaaccg caggcgattt ccatgctgcg cgcggtgctg gcggactcta acgatatttc
    72481 tctgcgggtg attccaacca aatatccttc tggcggtgct aaacaattaa cctacattct
    72541 gaccgggaag caggttccac atggcgggcg ttcatccgat atcggcgtat taatgcaaaa
    72601 cgtcggcact gcttatgcag tgaaacgtgc cgttattgat ggcgagccga ttaccgagcg
    72661 tgttgtaacc ctgactggcg aagcaatcgc tcgcccgggc aacgtctggg cacggctggg
    72721 gacgccagtg cgtcatttat tgaatgatgc cggattctgc ccctctgccg atcaaatggt
    72781 gattatgggt ggcccgctaa tgggctttac cttgccatgg ctggatgtcc cggtcgtaaa
    72841 gattaccaac tgtctgttgg ctccctctgc caatgaactt ggcgaaccac aggaagaaca
    72901 aagctgcatc cggtgtagcg cctgtgctga cgcctgccct gcggatcttt tgccgcaaca
    72961 gttgtactgg ttcagcaaag gtcagcaaca cgataaagct accacgcata acattgctga
    73021 ttgcattgaa tgtggggctt gcgcgtgggt ttgcccgagc aatattcccc tggtgcaata
    73081 tttccgtcag gaaaaagctg aaattgcggc tattcgtcag gaagaaaagc gcgccgcaga
    73141 agccaaagcg cgtttcgaag cgcgccaggc tcgtctggag cgcgaaaaag cggctcgcct
    73201 tgaacgacat aagagcgcag ccgttcaacc tgcagccaaa gataaagatg cgattgctgc
    73261 cgctctggcg cgggtgaaag agaaacaggc ccaggctaca cagcctattg tgattaaagc
    73321 gggcgaacgc ccggataaca gtgcaattat tgcagcacgg gaagcccgta aagcgcaagc
    73381 cagagcgaaa caggcagaac tgcagcaaac taacgacgca gcaaccgttg ctgatccacg
    73441 taaaactgcc gttgaagcag ctatcgcccg cgccaaagcg cgcaagctgg aacagcaaca
    73501 ggctaatgcg gaaccagaag aacaggtcga tccccgcaaa gccgccgtcg aagccg
//
LOCUS       DAZUDJ010000016        73028 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.016, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000016 DAZUDJ010000000
VERSION     DAZUDJ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 73028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73028
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.016"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..623
                     /locus_tag="ACHY1N_001532"
     CDS             <1..623
                     /locus_tag="ACHY1N_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043862.1"
                     /translation="VCNPFYSLINKREVLQSIDKVHYSMNSSHHAEVFVYAWLHKMLD
                     GIKGQYKDVNEIEDVSELPSDKLITIHYMVKGEASVYRYSKGMRITDSKGVLGLGSPG
                     LYYMDFLSVFSCLRNTNLFDLKIESISDENISLVKGLYNFKDENPLMYALMSIRINLE
                     FINNDGLSFYYISVDSCKKITALHEQKLRLSFNDKKPMDDIGELSD"
     gene            complement(886..1161)
                     /locus_tag="ACHY1N_001533"
     CDS             complement(886..1161)
                     /locus_tag="ACHY1N_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HFS4043863.1"
                     /translation="MVNMRVFKIKCPECGSPAIIRKSDWKDKKLASLYCGCTEVECGH
                     TFVYSVEFSHTLSPSGLTGNKLVKFLIDRLKPEERQFALDLLSGQTT"
     gene            complement(1209..2270)
                     /locus_tag="ACHY1N_001534"
     CDS             complement(1209..2270)
                     /locus_tag="ACHY1N_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4043864.1"
                     /translation="MTKKQRNNKKFRSMTGSKVESFTPGRGSVITFGEPEPILTTGTD
                     YHNIWYDNEYDHWRLPIDRLALAQLPNLNGQHGGVLYARRNMVAGGYIGGGLTPDQVE
                     QAVFDYLLFGDVAILKIRNVFGEVIDLLPLPSLYLRCRKDGAFAVLQEGPALIYEPED
                     IVFFKMYDPRQQVYGLPDYIGGIHSVLLNSEATIFRRRYYNNGAHMGFILYTSDPNLT
                     LEMENEIKEKIAQSKGLGNFRNMFINIPKGDPEGVKIMPVGEVSAKDEFANIKGITAQ
                     DIFTAHRFPAGLAGIIPTNGAVMGNPETARTTYRKDEVIPLQRKLMNGVNNDPEIPAH
                     LHLVFDVDIPAIATEKGEK"
     gene            complement(2267..4078)
                     /locus_tag="ACHY1N_001535"
     CDS             complement(2267..4078)
                     /locus_tag="ACHY1N_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase family protein"
                     /protein_id="HFS4043865.1"
                     /translation="MAKYSDELKEAARTLYMKSWTPKDIAQELNIPPRTIYHWADVGK
                     WASLLPVESVENVIARRIDQLSRREKKTALELEELRDLIAHHVKLMAQRNKHAEKLAE
                     IQAQKAAYDGEGYCLSSAGGEPEERKRRYKKNDVSGITPEMLDTWAREHLFEYQLHCR
                     EHKGEDWRFILKSRQVGMTYYFAWEAFEDAVITGDNQVFFSASRSQSEIFREYIVQIA
                     QNHFGVTLTGKNIRLSNGAILRFLSTNASTAQGFNGHLYGDEVFWIPKFTRLHEVASA
                     MATHNKYRTTYFSTPSAKTHQAYPVWTGEAWRGDDPKRKGVAFPTESEMRQGILCPDQ
                     IWRYIITMEDAIEGGLGALVDIERLRNKYSPTAFAMLYMCQFVDSKDAVFKFSALVGC
                     EVDRATWGDFDLTAARPFGNREVWAGFDPSRSGDNSTFVLIAPPIEDGERFRVLAVWQ
                     WRGFNFSWQADQIKQLMRRFNITYIGIDTTGIGKGVYDLVSKFAPREATPILYSVESK
                     NRLVMKMIDVVERKRIEWAKDAVDETNKERVEIPASFMAIRRTTTNSGNALTFVAERS
                     DATGHADVFFAISHAVINEPIDHEYDRPSGWYFGKAA"
     gene            4255..5316
                     /locus_tag="ACHY1N_001536"
     CDS             4255..5316
                     /locus_tag="ACHY1N_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HFS4043866.1"
                     /translation="MPQSHYRTDWLCIATSGKAVDGRTIEPQWLIDAAETYTRKTYTA
                     MIWPHHPQCDISEREFTCNLGEVDALKVETEGDVTKLYAQLIPNQFLIDANRQGQKLF
                     TSAEFVTDFAGSGREYLFGLAVTDIPASLGTEKLKFVLAGEEKDAERGSLETFSLGKL
                     QTSKPDKKNSFWSRLFSASKDFTPTPEPNTDKPTEGDGEKMEELKALIQQMLDLLKSG
                     KDAATGDADTVDTPEQAADVVADVAAQIADAADEVAELAQDVIENPEDEVKAEEFSAA
                     KANLAKVMKSFNVTPAKRPRASRRRDFSARRQPAGNQMDNLTTQLTTVLTKLSAMENG
                     NTRRPGSAPGGSKEPFEFV"
     gene            5345..6367
                     /locus_tag="ACHY1N_001537"
     CDS             5345..6367
                     /locus_tag="ACHY1N_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001177622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019028 - viral capsid [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HFS4043867.1"
                     /translation="MQLTPKAEQMLRKFAAGLAKANGQVDTSRYFSLTNPKETQLRNA
                     LLQSSEFLRLLPNVLDVDQITGQVVSTGKPGIYTGRKKDGRFSRALGVSGNEYKLVET
                     DSGSYLPYSLLVVWANAGSEEEFFQRIQAFSNESFALDMLRVAFNGTSVAEDTDPEAN
                     PNGEDVNIGWHKIVKDRSSEQIISDAVTIGASGADFIGLDAAVTDLVHTCIYEPFRND
                     PRLVVLASADLIGNDATTMMNKIDRPTEKVAAQLIGRQIAGRTVYTPPFMPEGRLIVT
                     TLDNLHIYTQQGTRKRKAEWNDDRKRFENNYLRMEGYGVEHDELYAAFDKITLATGEV
                     APGGGA"
     gene            6370..7071
                     /gene="gpM"
                     /locus_tag="ACHY1N_001538"
     CDS             6370..7071
                     /gene="gpM"
                     /locus_tag="ACHY1N_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFS4043868.1"
                     /translation="MAMTPCQRHRARVKATKALDKCEALTASPVSFHIQMLELERDVE
                     RLRSLTRAERMDMKRDVLLPRWMPTVEAYLAGDARFANPALVYCVIWLFDTGEMGKAL
                     DWADVAISESQATPENFKSNLPAFVADTVLEWAIMQAEAGHSIEPYFSRTFENIREKW
                     RLHEDINAKWFKFAGLYLLRDEKGQPRATAVDDVNTLEQADALLAQAAAYNKNAGVKT
                     MREKIRARINGLTQL"
     gene            7174..7647
                     /locus_tag="ACHY1N_001539"
     CDS             7174..7647
                     /locus_tag="ACHY1N_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006624209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HFS4043869.1"
                     /translation="MSGPSFSISGKPVTVTPTAITNGVTFWPDLDLAEFQKVRTLPAD
                     LPPETAGVALLAAIAEVNDALADVVTYWNAKACERAADVPGAKMGDETQLTAQYKKAV
                     YARAKADLLGEFATIGRRESHPGQESQDTRASLLAEAANVMRNMLRQPRVGVHLI"
     gene            7644..8120
                     /locus_tag="ACHY1N_001540"
     CDS             7644..8120
                     /locus_tag="ACHY1N_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4043870.1"
                     /translation="MSQLESLTAFITANLPPDAMQMFSSSMEDCELVRNAKALGNNQR
                     RIGVLTYTARLSWDDFPYRKYSPGLIYALVLAWVDEFANELRDELKLADPTVDPEFDD
                     EGSCILDVVVPLVDPLVLREVEKGPIPFKGKKWDIVNPEIWEASQLEFIVQRGDAS"
     gene            8156..8812
                     /locus_tag="ACHY1N_001541"
     CDS             8156..8812
                     /locus_tag="ACHY1N_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043871.1"
                     /translation="MRETLAKADLPPRKRQRLLWRIAKLGIVAAAKRHQRQQAAPDGT
                     PWEPRKRGKGKMLKGLPKLLAVREMPEIQGVRIYLKGGNYRNGTKPIAAGLVGAVQQD
                     GARIQMKASNAPRKPQADKPALPRQAKRLRALGYKTRKGKRWVKPSSKQIMETMSMAQ
                     AGLLIRKLKGTPSKRTWTIDIPGRVFLGVSNDEFNQIIARQMQAIGFGWDVNAQQIRG
                     "
     gene            8815..9957
                     /locus_tag="ACHY1N_001542"
     CDS             8815..9957
                     /locus_tag="ACHY1N_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2586 domain-containing protein"
                     /protein_id="HFS4043872.1"
                     /translation="MTWPNVNVSQKNRFNGTTNDVERVILFVGYGDTNIGKTQSLNTG
                     SDLDKALGDKDSPLKNMVAAAANNAGQNWFAYVHVLAEPDKEAEGYKPDEDWMNAVKM
                     AQSVASVEGVFLVFDTDEVATINRATEMRITLQANYGRFIWFGLAIGGPKQGEAWADY
                     VTRLAQLQDGIASPGVQLVPRLWGNEPGVLAGRLCNRSVTVADSPARVATGAVTALGR
                     DKLPVDGTGAEIDLSVLQSLQVNRYSVPMWYHDYDGIYWADGRTLDVEGGDYQVIENV
                     RVVDKASRRVRLRAIPKIADRSLNSTPGSIAAHETYFGKPLREMAISTQINGVEFPGE
                     VKPPKDGDITITWTSSEAVQIYLVVRPYESAKEISVSIELDTSLES"
     gene            9961..10416
                     /locus_tag="ACHY1N_001543"
     CDS             9961..10416
                     /locus_tag="ACHY1N_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage protein"
                     /protein_id="HFS4043873.1"
                     /translation="MTERISGGSFDVNYDSIMIHVENATVTITDNSAVAQSRGIPNGH
                     TKGSVSADVEVEVDSQSFKKFTAVARAAGSWRAIPAKDFLFYANAGDDEEKIEVFGCV
                     PTLSDIVNINPNEASKTTKKIKFMVTSPDFVAIDGVPYLSARDTRDLKG"
     gene            10421..10732
                     /locus_tag="ACHY1N_001544"
     CDS             10421..10732
                     /locus_tag="ACHY1N_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000980878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HFS4043874.1"
                     /translation="MMNGETSLLEKLLLIGAVIGLGQLMVSNERITTRLLVGRMILGS
                     AVAPLAAIPLLKFPDMPELVVIGLACALGILGSAFIEAGLKRCLDMYIKRWGSKRNET
                     E"
     gene            10719..11057
                     /locus_tag="ACHY1N_001545"
     CDS             10719..11057
                     /locus_tag="ACHY1N_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007710822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFS4043875.1"
                     /translation="MKLSEKQQLFTVMIASLIHFAQEKGYRLTFGEAYRTPEQAALNA
                     KKGSGITNSLHTQRLAVDFNLFINGEYQTDSAAYRPLGEYWESIGGSWGGRFSKPDGN
                     HFSLEHNGVR"
     gene            11057..11440
                     /locus_tag="ACHY1N_001546"
     CDS             11057..11440
                     /locus_tag="ACHY1N_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043876.1"
                     /translation="MRNLLGLLLILAAAMSAGWQAHDWHDAKLKLAASEAAEQTRQIV
                     VEVTQQSGEALEAKLAELRANEIHTERVIRTETIKSVFSNVCASDDYVRLFNESADQA
                     ERKLSGKPAGTLPGHVATSGRTDRK"
     gene            11543..11812
                     /locus_tag="ACHY1N_001547"
     CDS             11543..11812
                     /locus_tag="ACHY1N_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phage tail assembly chaperone"
                     /protein_id="HFS4043877.1"
                     /translation="MSKSKKIAMTVAGVNLSFEPNKTAFNNLLNEMTMTNKVAPMVTY
                     LGRIVDAECKEALNKLMEDYPGCEMQIVEKVNEIYSPKLEIEVKN"
     gene            11863..12000
                     /locus_tag="ACHY1N_001548"
     CDS             11863..12000
                     /locus_tag="ACHY1N_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043878.1"
                     /translation="MRRYYLPHEDDDEESIARALWLDEYFAQTRASKTAEGIAIAFNG
                     N"
     gene            12002..14116
                     /locus_tag="ACHY1N_001549"
     CDS             12002..14116
                     /locus_tag="ACHY1N_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4043879.1"
                     /translation="MSHLDFTLSLIDKLTRPLKTAQSSLSGFAEKSQESFTKIGIGAA
                     AVWGVAQSIAGVVGPAYEMNAALAEVGSKGVAEDALKRMSGEAMRFSMRYGKGAVDVV
                     RSSYAMKGAMAGLSDLDLPRVTIAANTLAAGVKASGEEAGEYIGAMASRFNAELSSLG
                     HVRFAEELAGKTAYMVQNFGVKMQTMQELIEGTKSAGADFGVSLDEQFAVLGTLSRTL
                     GTEASGIYEQFLRSAPAAAEKLGMSFVDATGKMLPMGDILQKLQNKYGQSIEGNVKAQ
                     QALDAAFGGGADVIKKLYGQQDKLNRSITELGRNDGMKRAQEMAERMAEPWERIKATF
                     FAIRVAIGNTLFPILSPLMNRIADVGTKFARWLDMFPNIARWLGYITLGVLSFGLAGA
                     AVNIVMGVFGFTMTGLAAIAKVLGGAWKLLLWTLNLLRPSLLTTRIGLAALWIQSKLL
                     ALWTGVCRIALAAWNIALKAGAIAMRVYGAATMFAGAAMQLLMSPITLIVAGLALLAV
                     GVWYVITHWEELAAAIMDTSAFAWVMSVAEQVGQVFAQVWQSITDGWAVVVDFFAGLS
                     PLATFEGFAQTIGGVFSKLFDVLKNTFASTYNWIVEKLNKIPGVNIDLKTVSPPAAAA
                     VPANAVIPDSAAGSSKLNSPSVLTGNRINAGIPRGGLMSQVKNDSKTAVDNRKTWGDT
                     YINAPNGITPAQLAEWQELNAG"
     gene            14113..14448
                     /locus_tag="ACHY1N_001550"
     CDS             14113..14448
                     /locus_tag="ACHY1N_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006624195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2590 family protein"
                     /protein_id="HFS4043880.1"
                     /translation="MSTEPLYIDLLITDGDFTLDSGNEPRRCDNRDSITQDIIHSILE
                     SGITTRLIGERSPTMRGDVLTQLSLLVESDERLVPGTIVITEETLSRLYITAETYDFG
                     PVSTEVNYD"
     gene            14441..15625
                     /locus_tag="ACHY1N_001551"
     CDS             14441..15625
                     /locus_tag="ACHY1N_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016507090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFS4043881.1"
                     /translation="MTEKPDVDFEKVLNDSGMPATEAEITAAFKATVQAEGFVTNTSR
                     MSPFWRLISKIVTTPVLWLRAALIDVVLRNMFVATATGPMLRLLAWAVHIEPKPASAA
                     AGVLRFFKLNAADVVVVPAGTLVQTERINGVVYVLAVNEDVTLPAGVESGLVPVTATG
                     TGSGYNLAPGYYRILPVAVAGIASAVNEDEWLITPGANEESDDELRDRTRNQFNLVGN
                     YHSDAIYRSMIASVLGLSIDRIYFLHDAPRGPGTANAYLLLDSGEISQPFIDAVNDYV
                     NTQGHHGHGDDLQCYAMPETSHTLAVTVYVKSVENMEAEDLSALKTGITDLIRCAFRE
                     NANYDVKKTQPYSRYSFSNLGREIHKAFPVVDSLHFSLTDIVSELSVPRLSGLTVEIE
                     ND"
     gene            15618..16211
                     /locus_tag="ACHY1N_001552"
     CDS             15618..16211
                     /locus_tag="ACHY1N_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4043882.1"
                     /translation="MTEFSKLLSGLKLPSWLNKGDPARLLRGSVKFWSQVYGWITWPL
                     KQFDPLVCPEPLLNLIAWERDIDRFKGEPLDIFRKRVSYAFINAQQAGEVAGFIAIFE
                     RLGIGYVELLERQDGLDWDVIVVRVTSSQVAENGDLLLEIIRKYGRTCRRYQFEVIDT
                     LPLNINIGWYQGEYICWPATLGDVNNQSEATYSASLK"
     gene            16223..18187
                     /locus_tag="ACHY1N_001553"
     CDS             16223..18187
                     /locus_tag="ACHY1N_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4043883.1"
                     /translation="MSQAVITKAFAEWKAQQAINNQPVTLDEFIFAYIPGLDADKPIN
                     NTETTPAEDKIVCRQAVNKAGVVNENSVVYSVTLGADVGDFDFNWIGLANKATGTLAM
                     IIHAPTQRKIKNADGQQGNVLVRSMLMEYSGAREATEINTPAETWQIDFTARLVGMDE
                     RQRRENIDLYGAAAFFDSGYLVAKSGNQFFVTKGAGYVAGLRAELPANFNITVSAKPT
                     KIWLDVSWTGTLTSEWAVQSKITVAADLADYVLGGVQHYVFAVASIDAAGNITDLRPK
                     GTLNDQAASDALKKHEQSRNHPDASTSEKGFVRLSSETNSDSEAMAVTPKALKAVNEN
                     ANGRVPASRKVNGHALNGDINVTSRDIFDGQVIAIGANKNLDDYQVPGLYFQEANNNT
                     SAAMNYPENSAGSLMVLRGAGVTQVYRVYNSSRSYSRSKYSTLAWTPWMPEDSYPVGA
                     PIPWPSDVTPTGYALMQGQPFDKAVYPLLAIAYPAGIIPDMRGQTIKGKPNGRAVLSY
                     EQDGVISHTHGASISDTDLGTKYTSSFDYGSKPTTSFDYGNKSSTEGGWHAHNFRYCA
                     TSAYRDTPGQGLGMHSSNVSWAAGDRIEGSGNHAHVTWIGPHDHWVGIGAHNHYVVMG
                     YHGHTATVHAAGNAENTVKNIAFNYIVRLA"
     gene            18187..18774
                     /locus_tag="ACHY1N_001554"
     CDS             18187..18774
                     /locus_tag="ACHY1N_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0098004 - virus tail fiber assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HFS4043884.1"
                     /translation="MTFEMTGENRTITIYNLRADTNEFIGKSDGFIPANTGLPANSTN
                     IAPPPMKAGFVAVFNSASEKWSLVEDHRGKIVYDILTGKSITIDELGQLPDDVVSVAP
                     EGHFVKWNGKKWVHDADAEKTAQITQATQQKDSLLALAASKIAPLQDAVDLDIATEEE
                     TALLLAWKKYRVLINRIKPEDAPDIDWPEVPGDVA"
     gene            18764..19492
                     /locus_tag="ACHY1N_001555"
     CDS             18764..19492
                     /locus_tag="ACHY1N_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043885.1"
                     /translation="MWRESVIKIADDMGALACSIVPAHPWVYGLGQNTDSGGYLSPAN
                     ALGYLAKKLLSGGGSGSGDVIVMMVAENTHDAFMQGLNKLSTVFPAPVFTQVSRMAAA
                     AAELSTVKMQLPVKADVLPASAPLSVSTNRLALNAQRVAAAQLAAAVSTTTTDLKNQV
                     TGFIQERAGLLSSLSQGLDDLKAASANIFAFSYSGSYAVAAAELLKGIPQTTAVHTAA
                     MMFIGDSLSDLGKMLHEPDRITRA"
     gene            19464..20006
                     /locus_tag="ACHY1N_001556"
     CDS             19464..20006
                     /locus_tag="ACHY1N_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043886.1"
                     /translation="MSQTALLALDGEGIAMQNMLVSPSMQFQEKDQSGQTSSTANAEQ
                     GIKAKELRVSGLVTFDDEAVLQRLFQLASATEASGALKKYRVANATATAINLREATFT
                     GQIDAVPQEDRLAWQVSFTLREKGSVPEKRQARKGNATASTKQTGAKGAGPAAGADEP
                     ADKMSWFEEKVLKPVNDALG"
     gene            20014..21738
                     /locus_tag="ACHY1N_001557"
     CDS             20014..21738
                     /locus_tag="ACHY1N_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043887.1"
                     /translation="MKPIKRLYLSSDPVHLIDCNIVLELNACGRGFITAGTETDYTGK
                     MVRIDVGYDGLVLRWFTGYVERSQPADNGTCRLFVRELVGIFDKLWPCSFQHPTLRQI
                     TDWISEQSGLTVTTPVGAAYADKPIPHFTHSGTGYQLFASLGRAFSVTDYLWYQLPDG
                     DVFVGAAEHSLFAGKPVEIPHEFSQESAGGNSMVVPMIQSLRPGAEVNGQRLNQVRLN
                     NDDMAITWQPRNKANGQPLQKSPIQRQIENAFPELASGLHLPRFARVEAPSEDVSGGD
                     IADPFRPRYAVDLQLLDEDGKPAANTPIYSAVPLPVPMAGSESGMFQFPPPGTLVEVG
                     FTEGRQDKPFVRQIMAEGHNLPAVKPGEQLQQQRDGVSQRVTVAGDWERQTDQTIREN
                     SMTREVTTDEEIRKVVARETTVQATDKTTVLGTATLLAGAVVHISEGDYSVGTSGNLT
                     VTCSKDNSVSVGRNVKRDVAGNVTDDVKGDVTSNVSGALTEKISGIRRSVAQAQQLIA
                     PVVKLGSEEINVLTLLTDTLDVVRELAETAASHTHPNTGASGQAAQFTATANKTGTLK
                     SKYGPLIA"
     gene            complement(22323..23288)
                     /locus_tag="ACHY1N_001558"
     CDS             complement(22323..23288)
                     /locus_tag="ACHY1N_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HFS4043888.1"
                     /translation="MKLYIIGNGFDLHHELDTSYFSFGDYLRKKDQDIYDHLVDFMGF
                     TDLPPKLSAVDKSKHFLWSDFENSLAGLDTESVLEEFCYLLPQISSPDFRDKDWGSLS
                     IEMERILKNLTEGLLTQFKSFILQVNYPELNLNKRLRIDSDSIFISFNYTETLQKYYG
                     IDDRQILYIHGKASSDQQLILGHGIDPINFEEKEAVPPENATDEELEEWRQCMADNYD
                     HSYEMGKQTINKYFTCSFKNTEKVIADSAKFFKNLSNVDEIIIIGHSLSSVDVPYFSF
                     IHSIVSENTEWIATYYQETEREAHHTTLCEIGIKSPKLISVSKLL"
     gene            complement(23625..24986)
                     /gene="yegQ"
                     /locus_tag="ACHY1N_001559"
     CDS             complement(23625..24986)
                     /gene="yegQ"
                     /locus_tag="ACHY1N_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HFS4043889.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
                     IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKY
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEHMENAKGEAMPIAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNP
                     HGK"
     gene            complement(25089..25385)
                     /locus_tag="ACHY1N_001560"
     CDS             complement(25089..25385)
                     /locus_tag="ACHY1N_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFS4043890.1"
                     /translation="MRIIKLMPKANEDLEGIWYYSYHHFGEPQADRYVEHLSDVLQIL
                     SNNNIGTPRPELGEGIFVLPFERHVIYFLQSPGEIIVIRILNQNQDATRHLHWS"
     gene            complement(25387..25683)
                     /locus_tag="ACHY1N_001561"
     CDS             complement(25387..25683)
                     /locus_tag="ACHY1N_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001307279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051983 - regulation of chromosome
                     segregation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
                     /protein_id="HFS4043891.1"
                     /translation="MTYTDVRFLLTGGRKMARTMTVDLGDELREFIESLIESGDYRTQ
                     SEVIRESLRLLREKQAESRLQALRDMLAEGLSSGEAQPWEKDAFLRKVKAGIRK"
     gene            complement(25892..26224)
                     /gene="yegP"
                     /locus_tag="ACHY1N_001562"
     CDS             complement(25892..26224)
                     /gene="yegP"
                     /locus_tag="ACHY1N_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HFS4043892.1"
                     /translation="MAGWFELSESSDNQFRFVLKAGNGETILTSELYTSKASAEKGIA
                     SVRSNSPQEERYEKKTASNGKFYFNLKAANHQIIGSSQMYATAQSRETGIASVKANGT
                     SQTVKDNT"
     gene            complement(26415..27137)
                     /gene="baeR"
                     /locus_tag="ACHY1N_001563"
     CDS             complement(26415..27137)
                     /gene="baeR"
                     /locus_tag="ACHY1N_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HFS4043893.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGD
                     QVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
                     LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRIV"
     gene            complement(27134..28537)
                     /gene="baeS"
                     /locus_tag="ACHY1N_001564"
     CDS             complement(27134..28537)
                     /gene="baeS"
                     /locus_tag="ACHY1N_001564"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HFS4043894.1"
                     /translation="MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIK
                     HGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQILRSFEHDNSEDKPGPGMPPHG
                     WRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
                     KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSED
                     ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPE
                     TVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASRG
                     LKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLQISAGQRDKTVRLTFAD
                     SAPGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGG
                     VSITVELPLERDLQREV"
     gene            complement(28534..29949)
                     /gene="mdtD"
                     /locus_tag="ACHY1N_001565"
     CDS             complement(28534..29949)
                     /gene="mdtD"
                     /locus_tag="ACHY1N_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4043895.1"
                     /translation="MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESP
                     LHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELL
                     LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEY
                     ASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSK
                     GTGLSPLTIAGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATT
                     LGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNS
                     LLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMALIIALPAFIF
                     ARVPNDTHQNVAISRRKRSAQ"
     gene            complement(29950..33027)
                     /gene="mdtC"
                     /locus_tag="ACHY1N_001566"
     CDS             complement(29950..33027)
                     /gene="mdtC"
                     /locus_tag="ACHY1N_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HFS4043896.1"
                     /translation="MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDIN
                     GAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST
                     QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG
                     ALEDGTHRWQIQTNDELKTADEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRSSLEEV
                     EQTLIISVALVILVVFLFLRSGRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRMRGFGRML
                     VALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQ
                     QIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRK
                     KLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGL
                     SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILI
                     IAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSG
                     GDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE"
     gene            complement(33028..36150)
                     /gene="mdtB"
                     /locus_tag="ACHY1N_001567"
     CDS             complement(33028..36150)
                     /gene="mdtB"
                     /locus_tag="ACHY1N_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HFS4043897.1"
                     /translation="MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVS
                     ALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM
                     TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAIT
                     GANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAE
                     NSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQN
                     RFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQD
                     NGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQ
                     INLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQAT
                     SLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTEITPGLAALDTIRLTSSDGGVVPLSSIAKV
                     EQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGST
                     LAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGS
                     ELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK
                     SCFARHEEEA"
     gene            complement(36150..37397)
                     /gene="mdtA"
                     /locus_tag="ACHY1N_001568"
     CDS             complement(36150..37397)
                     /gene="mdtA"
                     /locus_tag="ACHY1N_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HFS4043898.1"
                     /translation="MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQ
                     QSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLMALH
                     FQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLV
                     SRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQIS
                     SGDTTGIVVITQTHPIDLLFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTL
                     LSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNE
                     GHFVWVLSSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVE
                     AQSATTPEEKATSREYAKKGARS"
     gene            37676..37732
                     /locus_tag="ACHY1N_001569"
     CDS             37676..37732
                     /locus_tag="ACHY1N_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HFS4043899.1"
                     /translation="MMKLLIIVVLLVISYPAY"
     gene            38004..38060
                     /locus_tag="ACHY1N_001570"
     CDS             38004..38060
                     /locus_tag="ACHY1N_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HFS4043900.1"
                     /translation="MMKLLIIVVLLVISFPAY"
     gene            38333..38392
                     /gene="ibsA"
                     /locus_tag="ACHY1N_001571"
     CDS             38333..38392
                     /gene="ibsA"
                     /locus_tag="ACHY1N_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsA"
                     /protein_id="HFS4043901.1"
                     /translation="MMKHVIILVILLVISFQAY"
     gene            38613..39272
                     /gene="yegL"
                     /locus_tag="ACHY1N_001572"
     CDS             38613..39272
                     /gene="yegL"
                     /locus_tag="ACHY1N_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HFS4043902.1"
                     /translation="MSEQITFATSDFASNPEPRCPCILLLDVSGSMSGRPINELNAGL
                     VTFRDELLADPLALKRVELGIVTFGPVHVEQPFTSAANFFPPILFAQGDTPMGAAITK
                     ALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFRGEEDKRFAFFSIG
                     VQGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTS
                     V"
     gene            39269..40030
                     /gene="pphC"
                     /locus_tag="ACHY1N_001573"
     CDS             39269..40030
                     /gene="pphC"
                     /locus_tag="ACHY1N_001573"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PP2C family serine/threonine-protein
                     phosphatase"
                     /protein_id="HFS4043903.1"
                     /translation="MSWRLVYASAVGTSHISADLPCQDACQMQVAWLNDQQPLLVMFL
                     ADGAGSVSQGGEGATLAVNEAMAYMSQKVQGGELGLNDILATDIVLTVRQRLFAEAEA
                     KELAVRDFACTFLGLISSANGTLIMQIGDGGVVVDFGHGLQLPLTPMVGEYANMTHFI
                     TDEDAVSRLETFTSTERVHKVAAFTDGIQRLALNMLDNSPHVPFFTPFFNGLASATQE
                     QLDLLPELLKQFLSSPAVNERTDDDKTLALALWLP"
     gene            40027..41967
                     /gene="yegI"
                     /locus_tag="ACHY1N_001574"
     CDS             40027..41967
                     /gene="yegI"
                     /locus_tag="ACHY1N_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310906.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YegI"
                     /protein_id="HFS4043904.1"
                     /translation="MKPTLYTATGECVTPGRELGKGGEGAVYDINEFVDSVAKIYHTP
                     PPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMIYS
                     PAHRRQRYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLIDS
                     DSFQINANGTLHLCEVGVSHFTPPELQTLSSFVGFERTENHDNFGLALLIFHVLFGGR
                     HPYSGVPLISDAGNALETDITHFRYAYASDNQRRGLKPPPRSIPLSMLPGDVEAMFQQ
                     AFTESGVATGRPTAKAWVAALDSLRQQLKKCPVSAMHVYPAHLTDCPWCALDNQGVIY
                     FIDLGEEVITTGGDFVLAKVWAMVMASVAPPALQLPLPDHFQPTGRPLPLGLLRREYI
                     ILIEIALSALSLLLCGLQAEPRYIILVPVLSAIWIIGSLTSKAYKAEIQQRREAFNRA
                     KMDYEHLVSQIQQLGGLEGFIAKRAMLEKMKDEILGLPEEEKRALAALHDTARERQKQ
                     KFLEGFFIDVASIPGVGPARKAALRSFGIETAADVTRRGVKQVKGFGDHLTQAVIDWK
                     ASCERRFVFRPNEAITPADRQAVMAKMTAKRHRLESTLTVGATELQRFRLHAPARTMP
                     LMEPLRQAAEKLAQAQADLSRC"
     gene            complement(41979..43331)
                     /gene="yegD"
                     /locus_tag="ACHY1N_001575"
     CDS             complement(41979..43331)
                     /gene="yegD"
                     /locus_tag="ACHY1N_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HFS4043905.1"
                     /translation="MFIGFDYGTANCSVAVMRDGKPQLLKMENDSTLLPSMLCAPTRE
                     SVSEWLYRHHDVPADDDETQALLRRAIRYNREEDIDVTAKSVQFGLSSLAQYIDDPEE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIRQQAQAQLPEAITQAVIGRPINF
                     QGLGGDEANAQAQGILERAAKRAGFRDVVFQYEPVAAGLDYEATLQEEKRVLVVDIGG
                     GTTDCSLLLMGPQWRSRLDREASLLGHSGCRIGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPILPWWNAVAINDVPAQSDFYSSANGRLLNDLVRDAREPEKVALLQKVWRQRLS
                     YRLVRSAEECKIALSSVAETRASLPFISDELATLISQQGLESALSQPLARILEQVQLA
                     LDNAQEKPDVIYLTGGSARSPLIKKALAEQLPGIPIAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            43465..44322
                     /gene="alkA"
                     /locus_tag="ACHY1N_001576"
     CDS             43465..44322
                     /gene="alkA"
                     /locus_tag="ACHY1N_001576"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HFS4043906.1"
                     /translation="MYTLNWQPPYDWSWMLGFLAARAVSGVETVAEDYYARSLAVGEY
                     RGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGKLGAAR
                     PGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTAKVVQLYGERLDDFPEYICFPTPQR
                     LAAADPQALKALGMPLKRAEALIHLANAALEGSLPMTIPGDVEQAMKTLQTFPGIGRW
                     TANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEG
                     WQPDGTDEL"
     gene            complement(44361..47678)
                     /gene="dgcE"
                     /locus_tag="ACHY1N_001577"
     CDS             complement(44361..47678)
                     /gene="dgcE"
                     /locus_tag="ACHY1N_001577"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFS4043907.1"
                     /translation="MSKQSQHVLIALPHPLLHLVSLGLVSFIFTLFSLELSQFGTQLA
                     PLWFPTSIMMVAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMTWTTINIVEAV
                     VGAVLLRKLLPWYNPLQNLADWLRLAFGSAIVPPLLGGVLVVLLTPGDDPLRAFLIWV
                     LSESIGALALVPLGLLFKPHYLLRHRNPRLLFESLLTLAITLTLSWLSMLYLPWPFTF
                     IIVLLMWSAVRLPRMEAFLIFLTTVMMVSLMMAADPSLLATPRTYLMSHMPWLPFLLI
                     LLPANIMTMVMYAFRAERKHISESETRFRNAMEYSAIGMALVGTEGQWLQTNKALCQF
                     LGYSQEELRGLTFQQLTWPEDLNKDLQQVEKLISGEINTYSMEKRYYNRNGDVVWALL
                     AVSLVRHTDGTPLYFIAQIEDINELKRTEQVNQQLMERITLANEAGGIGIWEWELKPN
                     IFSWDKRMFELYEIPPHIKPNWQVWYECVLPEDRQHAEKVIRDSLQSRSPFKLEFRIT
                     VKDGIRHIRALANRVLNKEGEVERLLGINMDMTEVKQLNEALFQEKERLHITLDSIGE
                     AVVCIDMAMKITFMNPVAEKMSGWTQEEALGVPLLTVLHITFGDNGPLMENIYSADTS
                     RSAIEQDVVLHCRSGGSYDVHYSITPLSTLDGSNIGSVLVIQDVTESRKMLRQLSYSA
                     SHDALTHLANRASFEKQLRMLLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALL
                     RELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAVNDYHFIWEGR
                     VHRVGASAGITLIDDNNHQAAEVMSQADIACYASKNGGRGRVTVYEPQQAAAHSERAA
                     MSLDEQWRMIKENQLMMMAHGVASPRIPEARNLWLISLKLWSCEGEIIDEQKFRRSFS
                     DPALSHALDRRVFHEFFQLAAKAVASKGISIALPLSVAGLSSATLVNDLLEQLENSPL
                     PPRLLHLIIPADAILDHAESVQKLRLAGCRIVLSQVGRDLQIFNSLKANMADYLLLDG
                     ELCANVQGNLMDEMLITIIQGHAQRLGMKTIAGPVVLPLVMDTLSGIGVDLIYGDVIA
                     DAQPLDLLVNSSYFAIN"
     gene            47996..48637
                     /gene="udk"
                     /locus_tag="ACHY1N_001578"
     CDS             47996..48637
                     /gene="udk"
                     /locus_tag="ACHY1N_001578"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFS4043908.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTR
                     MKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            48729..49310
                     /gene="dcd"
                     /locus_tag="ACHY1N_001579"
     CDS             48729..49310
                     /gene="dcd"
                     /locus_tag="ACHY1N_001579"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008829 - dCTP deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006229 - dUTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HFS4043909.1"
                     /translation="MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPAD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRREDAKYRNQQGAVASRIDKD"
     gene            49332..51185
                     /gene="asmA"
                     /locus_tag="ACHY1N_001580"
     CDS             49332..51185
                     /gene="asmA"
                     /locus_tag="ACHY1N_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HFS4043910.1"
                     /translation="MRRFLTTLMILLVVLVAGLSALVLLVNPNDFRDYMVKQVAARSG
                     YQLQLDGPLRWHVWPQLSILSGRMSLTAQGASQPLVRADNMRLDVALLPLLSHQLSVK
                     QVMLKGAVIQLTPQTEAVRSEDAPVAPRDNTLPDLSDDRGWSFDISSLKVADSVLVFQ
                     HEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTISLNGTVDASDYPHDLTA
                     AIEQINWQLQGADLPKQGIQGQGSFQAQWQESHKRLSFNQISLTANDSTLSGQAQVTL
                     TEKPEWQLRLQFPQLNLDNLIPLNETANGENGAAQQGQSQSTLPRPVISSRIDEPAYQ
                     GLQGFTADILLQASNVRWRGMNFTDVATQMTNKSGLLEITQLQGKLNGGKVSLPGTLD
                     ATSINPRINFQPRLENVEIGTILKAFNYPISLTGKMSLAGDFSGADIDADAFRHNWQG
                     QAHVEMTDTRMEGMNFQQMIQQAVERNGGDVKAAENFDNVTRLDRFTTDLTLKDGVVT
                     LNDMQGQSPVLALTGEGMLNLADQTCDTQFDIRVVGGWNGESKLIDFLKETPVPLRVY
                     GNWQQLNYSLQVDQLLRKHLQDEAKRRLNDWAERNKDSRNGKDVKKLLEKM"
     gene            complement(51636..53219)
                     /gene="yegH"
                     /locus_tag="ACHY1N_001581"
     CDS             complement(51636..53219)
                     /gene="yegH"
                     /locus_tag="ACHY1N_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416567.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HFS4043911.1"
                     /translation="MEWIADPSIWAGLITLIVIELVLGIDNLVFIAILAEKLPPKQRD
                     RARVTGLLLAMLMRLLLLASISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKAT
                     MELNERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVITAVGMVDHLLVMMAA
                     VVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAI
                     GFSVMIEALNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLVD
                     HGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEEEIRQLLERNQHT
                     RLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHR
                     VQKVQIIPLRKDGEMEYEV"
     gene            complement(53420..53569)
                     /locus_tag="ACHY1N_001582"
     CDS             complement(53420..53569)
                     /locus_tag="ACHY1N_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043912.1"
                     /translation="MVIEYWLSNNAGGSVTANGIAGKVTIRQLAIFKNYIKCHSIWFL
                     GVSLG"
     gene            53878..55017
                     /gene="wza"
                     /locus_tag="ACHY1N_001583"
     CDS             53878..55017
                     /gene="wza"
                     /locus_tag="ACHY1N_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein Wza"
                     /protein_id="HFS4043913.1"
                     /translation="MMKSKMKLMPLLVSVTLISGCTVLPGSNMSTMGKDVIKQQDADF
                     DLDKMVNVYPLTPRLIDQLRPRPNVARPNMTLESEIANYQYRVGPGDVLNVTVWDHPE
                     LTTPAGQYRSSSDTGNWVQPDGTMFYPYIGKIHVVGKTLAEIRSDITGRLATYIADPQ
                     VDVNIAAFRSQKAYISGQVNKSGQQAITNVPLTILDAINAAGGLTDTADWRNVVLTHN
                     GREERISLQALMQNGDLNQNRLLYPGDILYVPRNDDLKVFVMGEVKKQSTLKMDFSGM
                     TLTEALGNAEGIDMTTSNASGIFVIRPLKGEGGRNGKIANIYQLDMSDATSLVMATEF
                     RLQPYDVVYVTTAPVSRWNRLINQLLPTISGVRYMTDTASDIHNW"
     gene            55023..55466
                     /gene="wzb"
                     /locus_tag="ACHY1N_001584"
     CDS             55023..55466
                     /gene="wzb"
                     /locus_tag="ACHY1N_001584"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase Wzb"
                     /protein_id="HFS4043914.1"
                     /translation="MFNNILVVCVGNICRSPTAERLLQRYHPELKVESAGLGALVGKG
                     ADPTAISVAAEHQLSLEGHCARQISRRLCRNYDLILTMEKRHIERLCEMAPEMRGKVM
                     LFGHWDNECEIPDPYRKSRETFAAVYTLLERSARQWAQALNAEQV"
     gene            55469..57631
                     /gene="wzc"
                     /locus_tag="ACHY1N_001585"
     CDS             55469..57631
                     /gene="wzc"
                     /locus_tag="ACHY1N_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310892.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wzc"
                     /protein_id="HFS4043915.1"
                     /translation="MTEKVKQHAAPVTGSDEIDIGRLVGTVIEARWWVIGITAVFALC
                     AVVYTFFATPIYSADALVQIEQSSGNSLVQDIGSALANKPPASDAEIQLIRSRLVLGK
                     TVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMADQVFTLNVLDDK
                     NYTLSSDGGFSARGQAGQMLKKEGVTLMVEAIHARPGSEFTVTKYSTLGMINQLQNSL
                     TVTENGKDAGVLSLTYTGEDREQIRDILNSIARNYQEQNIERKSAEASKSLAFLAQQL
                     PEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNELTFKEAEISKLY
                     TKVHPAYRTLLEKRQALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNK
                     EQELKITEASTVGDVRIVDPAITQPGVLKPKKGLIILGAIILGLMLSIVGVLLRSLFN
                     RGIESPQVLEEHGISVYASIPLSEWQKARDSVKTIKGIKRYKQSQLLAVGNPTDLAIE
                     AIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLLIDCDMR
                     KGYTHELLGTNNVNGLSEILIGQGDITTAAKPTSIAKFDLIPRGQVPPNPSELLMSER
                     FAELVNWASKNYDLVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSR
                     FEQNGIPVKGVILNSIFRRASAYQDYGYYEYEYKSDAK"
     gene            57809..58648
                     /gene="wcaA"
                     /locus_tag="ACHY1N_001586"
     CDS             57809..58648
                     /gene="wcaA"
                     /locus_tag="ACHY1N_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaA"
                     /protein_id="HFS4043916.1"
                     /translation="MKDNPLISIYMPTWNRQQLAIRAIKSVLRQDYSNWEMIIVDDCS
                     TSWEQLQQYVTALNDPRITYIHNDINSGACAVRNQAIMLAQGEYITGIDDDDEWTPNR
                     LSVFLAHKQQLVTHAFLYANDYVCQGEVYSQPASLPLYPKSPYSRRLFYKRNIIGNQV
                     FTWAWRFKECLFDTELKAAQDYDIFLRMVVEYGEPWKVEEATQILHINHGEMQITSSP
                     KKFSGYFHFYRKHKDKFDRASKKYQLFTLYQIRNKRMTWRTLLTLLSVRNGKRLADGI
                     RGR"
     gene            58651..59139
                     /gene="wcaB"
                     /locus_tag="ACHY1N_001587"
     CDS             58651..59139
                     /gene="wcaB"
                     /locus_tag="ACHY1N_001587"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaB"
                     /protein_id="HFS4043917.1"
                     /translation="MLEDLRANSWSLRPCCMVLAYRVAHFCSVWRKKNVLNNLWAAPL
                     LVLYRIITECFFGYEIQAAATIGRRFTIHHGYAVVINKNVVAGDDFTIRHGVTIGNRG
                     ADNMACPHIGNGVELGANVIILGDITLGDNVTVGAGSVVLDSVPDNALVVGEKARVKV
                     IK"
     gene            59136..60353
                     /gene="wcaC"
                     /locus_tag="ACHY1N_001588"
     CDS             59136..60353
                     /gene="wcaC"
                     /locus_tag="ACHY1N_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaC"
                     /protein_id="HFS4043918.1"
                     /translation="MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKGGK
                     ESVSHQNYPQVIKHTPRMTAMANIALFRLFNRDLFGNFNELYRTITRTPGPVVLHFHV
                     LHSYWLNLKSVVRFCEKVKNHKPDITLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP
                     TLNNYPPVKIDRAHQLVAGKRQLFREMLALGCQFISPSQHVADAFNSLYGPGRCRIIN
                     NGIDMATEAILADLPPVRETQGKPKIAVVAHDLRYDGKTNQQLVREMMALGDKIELHT
                     FGKFSPFTAGNVVNHGFETDKRKLMSALNQMDALVFSSRVDNYPLILCEALSIGVPVI
                     ATHSDAAREVLQKSGGKTVDEEEVLQLVQLSKPEIAQAIFGTTLAEFSQRSRATYSGQ
                     QMLEEYVNFYQNL"
     gene            60328..61545
                     /gene="wcaD"
                     /locus_tag="ACHY1N_001589"
     CDS             60328..61545
                     /gene="wcaD"
                     /locus_tag="ACHY1N_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid polymerase WcaD"
                     /protein_id="HFS4043919.1"
                     /translation="MSTSIRICSYLLLPLIYLLVNVKIAQLGESFPITIVTFLPVLLL
                     LFLERISVKKLMIALGIGAGLTAFNYLFGQSLDASKYVTSTMLFVYIVIIIGMVWSIR
                     FKTISPHNHRKILRFFYLVVGLVVALAAVEMAQIILTGGSSIMESISKYLIYSNSYVL
                     NFIKFGGKRTTALYFEPAFFALALISIWLSIKQFGIKTPKTDAMILAGIILSGSFSGV
                     MTFILFYLLEWAFQYLNKEAIKKKLPLALISLAVFLVGVVIAFPYISTRLGDLGTEGS
                     SSYYRIVGPLVMVGYSLTHIDGVVRFGSLYEYVASFGIFNGADVGKTIDNGLYLLIIY
                     FSWSAVFLSLWYMGKVIKMMINAFGDNRNFRVQLYLFTPVSLFFTGSIFSPEYAFLIV
                     CPFILRKALNITR"
     gene            61556..62302
                     /gene="wcaE"
                     /locus_tag="ACHY1N_001590"
     CDS             61556..62302
                     /gene="wcaE"
                     /locus_tag="ACHY1N_001590"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaE"
                     /protein_id="HFS4043920.1"
                     /translation="MLLSIITVAFRNLEGIVKTHASLAHLAQAEDISFEWIVVDGGSN
                     DGTREYLENLNGIYNLRFVSEPDNGIYDAMNKGITMAQGKFALFLNSGDIFHQDAANF
                     VRKLKMQKDNMMITGDALLDFGDGHKIKRSAKPGWYIYHSLPASHQAIFFPVSGLKKW
                     RYDLEYKVSSDYALAAKMYKAGYAFKKLNGLVSEFSMGGVSTTNNMELCADAKKVQRQ
                     ILHVPGFWAELSWHLRQRTTSKTKALYNKV"
     gene            62318..62866
                     /gene="wcaF"
                     /locus_tag="ACHY1N_001591"
     CDS             62318..62866
                     /gene="wcaF"
                     /locus_tag="ACHY1N_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaF"
                     /protein_id="HFS4043921.1"
                     /translation="MQDLSGFSVPKGFRGGNAIKVQLWWAVQATIFAWSPQVLYRWRA
                     FLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYAWVGDDVNLYTLGEITIGAHSVISQ
                     KSYLCTGSHDHASQHFTINATPIVIGEKCWLATDVFVAPGVTIGDGTVVGARSSVFKT
                     LPANVVCRGNPAVVIRERVETE"
     gene            62893..64014
                     /gene="gmd"
                     /locus_tag="ACHY1N_001592"
     CDS             62893..64014
                     /gene="gmd"
                     /locus_tag="ACHY1N_001592"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008446 - GDP-mannose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019673 - GDP-mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HFS4043922.1"
                     /translation="MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYL
                     GNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRF
                     EGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWK
                     PEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES"
     gene            64017..64982
                     /gene="fcl"
                     /locus_tag="ACHY1N_001593"
                     /gene_synonym="wcaG"
                     /gene_synonym="yefB"
     CDS             64017..64982
                     /gene="fcl"
                     /locus_tag="ACHY1N_001593"
                     /gene_synonym="wcaG"
                     /gene_synonym="yefB"
                     /EC_number="1.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HFS4043923.1"
                     /translation="MSKQRIFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDS
                     RAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKL
                     LFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
                     VMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMA
                     AASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASK
                     PDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFRG"
     gene            64985..65464
                     /gene="gmm"
                     /locus_tag="ACHY1N_001594"
                     /gene_synonym="nudD"
                     /gene_synonym="wcaH"
                     /gene_synonym="yefC"
     CDS             64985..65464
                     /gene="gmm"
                     /locus_tag="ACHY1N_001594"
                     /gene_synonym="nudD"
                     /gene_synonym="wcaH"
                     /gene_synonym="yefC"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="HFS4043924.1"
                     /translation="MFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQGY
                     WFVPGGRVQKDETLEAAFERLTMAELGLRLPITAGQFYGVWQHFYDDNFSGTDFTTHY
                     VVLGFRFRVAEEDLILPDEQHDDYRWLTPDALLASNDVHANSRAYFLAEKRAGVPGL"
     gene            65461..66684
                     /gene="wcaI"
                     /locus_tag="ACHY1N_001595"
     CDS             65461..66684
                     /gene="wcaI"
                     /locus_tag="ACHY1N_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis fucosyltransferase
                     WcaI"
                     /protein_id="HFS4043925.1"
                     /translation="MKILVYGINYSPELTGIGKYTGEMVEWLAAQGHEVRVITAPPYY
                     PQWQVGENYSAWRYKREEGAATVWRCPLYVPKQPSTLKRLLHLGSFAVSSFFPLMAQR
                     RWKPDRIIGVVPTLFCTPGMRLLAKLSGARTVLHIQDYEVDAMLGLGLAGKGKGSKVA
                     QLATAFERSGLHNVDNVSTISRSMMNKAIEKGVAAENVIFFPNWSEIARFQHVADADV
                     DALRNQLDLPDNKKIILYSGNIGEKQGLENVIEAADRLRDEPLIFAIVGQGGGKARLE
                     KMAQQRGLRNMQFFPLQSYDALPALLKMGDCHLVVQKRGAADAVLPSKLTNILAVGGN
                     AVITAEAHTELGQLCETFPGIAVCVEPESVEALVAGIRQALLLPKHNTVAREYAERTL
                     DKENVLRQFINDIRG"
     gene            66687..68123
                     /gene="cpsB"
                     /locus_tag="ACHY1N_001596"
     CDS             66687..68123
                     /gene="cpsB"
                     /locus_tag="ACHY1N_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanyltransferase"
                     /protein_id="HFS4043926.1"
                     /translation="MAQSKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTT
                     ICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAA
                     TRHSPESDPLMLVLAADHVIADEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGY
                     IRRGEVSAGEQDTVAFEVAQFVEKPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELK
                     KYRPDILDACEKAMSAVDPDLDFIRVDEEAFLACPEESVDYAVMERTADAVVVPMDAG
                     WSDVGSWSSLWEISAHTAEGNVCHGDVINHKTENSYVYAESGLVTTVGVKDLVVVQTK
                     DAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVKRITV
                     KPGEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGATHCLENPGKI
                     PLDLIEVRSGSYLEEDDVVRFADRYGRV"
     gene            68316..69686
                     /gene="cpsG"
                     /locus_tag="ACHY1N_001597"
                     /gene_synonym="manB"
     CDS             68316..69686
                     /gene="cpsG"
                     /locus_tag="ACHY1N_001597"
                     /gene_synonym="manB"
                     /EC_number="5.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis phosphomannomutase
                     CpsG"
                     /protein_id="HFS4043927.1"
                     /translation="MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLG
                     GDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLF
                     GYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIP
                     NPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAQPVEAINR
                     VEQHFSREALAVDRTDGISMTFADWRFNLRTSNTEPVVRLNVESRGDVPLMEARTRTL
                     LTLLNE"
     gene            69741..71135
                     /gene="wcaJ"
                     /locus_tag="ACHY1N_001598"
     CDS             69741..71135
                     /gene="wcaJ"
                     /locus_tag="ACHY1N_001598"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HFS4043928.1"
                     /translation="MTNLKKRERAKTNASLISMVQRFSDITIMFAGLWLVCEVSGLSF
                     LYMHLLVALITLVVFQMLGGITDFYRSWRGVRAATEFALLLQNWTLSMIFSAGLVAFN
                     NDFDTQLKIWLAWYGLTSIGLVVCRSCIRIGAGWLRNHGYNKRMVAVAGDLAAGQMLM
                     ESFRNQPWLGFEVVGVYHDPKPGGVSNDWAGNLQQLVEDAKAGKIHNVYIAMQMCDGA
                     RVKKLVHQLADTTCSVLLIPDVFTFNILHSRLEEMNGVPVVPLYDTPLSGVNRLLKRA
                     EDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGKPIKVWKFRSMKVME
                     NDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYR
                     QLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIV
                     FLTVFKGFVNKAAY"
     gene            71137..72615
                     /gene="wzxC"
                     /locus_tag="ACHY1N_001599"
     CDS             71137..72615
                     /gene="wzxC"
                     /locus_tag="ACHY1N_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid undecaprenyl disphosphate flippase
                     WzxC"
                     /protein_id="HFS4043929.1"
                     /translation="MSLREKTISGAKWSAIATVIIIGLGLVQMTVLARIIDNHQFGLL
                     TVSLVIIALADTLSDFGIANSIIQRKEISHLELTTLYWLNVGLGLVVCVAVFLLSDAI
                     GDVLNNPDLAPLIKTLSLAFVVIPHGQQFRALMQKELEFNKIGMIETSAVLAGFTFTV
                     VSAHFWPLAMTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVAPNLRFGAWLTA
                     DSIINYLNTNLSTLVLARILGAGVAGGYNLAYNVAVVPPMKLNPIITRVLFPAFAKIQ
                     DDTEKLRVNFYKLLSVVGIINFPALLGLMVVSNNFVPLVFGEKWNSIIPVLQLLCVVG
                     LLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAIVIGGQMAGAIGVTLGFLLVQI
                     INTILSYFVMIKPVLGSSYRQYILSLWLPFYLSLPTLGVSYALGIVLKGQLALGMLLA
                     VQIAAGVLAFVVMIVLSRHPLVVEVKRQFCRSEKMKMLLRAG"
BASE COUNT        17572 a        18709 c        19963 g        16784 t
ORIGIN      
        1 ttgtctgcaa tccattctat tcattgatta ataagagaga agtcttgcag tcaattgata
       61 aagtgcatta ttcaatgaat agttcacatc atgctgaagt gtttgtctat gcttggcttc
      121 ataaaatgct tgatggaatt aaaggccaat ataaagatgt aaatgagatc gaagatgtaa
      181 gtgaactacc ttccgataag cttataacaa ttcattacat ggttaaagga gaggcaagtg
      241 tttaccgtta ctcaaaaggt atgagaataa cagattcaaa aggagttttg ggtttggggt
      301 ctcctggtct ttactacatg gattttttga gcgtattttc ctgtctgcgg aatactaatt
      361 tatttgattt gaaaattgaa agtatttctg atgagaatat ttccttagtt aaggggttgt
      421 ataatttcaa ggatgaaaat ccattgatgt acgcgctgat gtctattagg attaatttgg
      481 aatttattaa taacgatggc ttgtcgtttt attatatttc tgtagatagt tgtaaaaaaa
      541 tcactgcatt acatgaacaa aaacttcgtc tatcttttaa tgataaaaaa ccaatggatg
      601 atattggtga actttcagat taaatgtaat gtatcattgt agagatttat tcttacagtg
      661 tttgaacgcg tttattcact aaggattgtt tctatgttgt ttatatagga tattgatagt
      721 gcgtaaaagt atgattttat aatgtgtagg caatgggctg gatagggcaa tcctttactt
      781 atttgaaaac cgccgcaatt tgaatgtgcg gcggagggat gtaatgtaca ttaggtgttc
      841 aaaggattga tgcttgcgcc gtacatctat gtgtagcagt gggatttatg tagtttgccc
      901 actgagcagg tccagcgcga attgacgttc ttccggcttg agccggtcaa tcaggaattt
      961 aaccagcttg ttgccggtca gcccgctggg gctgagggta tgtgaaaact caacgctata
     1021 aacaaatgta tgaccacatt ccacttctgt gcagccacag tataaagacg ccagtttttt
     1081 atctttccag tcagatttgc gaatgatggc cggtgagccg cattcaggac atttaatttt
     1141 aaaaactcgc atgttcacca tcccgcacgc cattgctaat aatggggggg attttaactt
     1201 aactgcgctc atttttcgcc cttttcggtg gcaattgccg ggatatccac gtcaaaaacc
     1261 aggtgcaagt gtgcggggat ctccgggtca ttattgacgc cgttcattag cttgcgctgc
     1321 aaggggataa cttcatcctt gcgataggtt gtgcgggcgg tttcagggtt gcccattacc
     1381 gcgccgttgg tcgggatgat acccgccagg ccagcgggga aacggtgggc ggtaaagata
     1441 tcctgcgcgg ttatcccttt gatgttggca aattcatcct ttgcgctgac ttcacccact
     1501 ggcatgattt taaccccttc cgggtcgccc ttcgggatgt tgataaacat atttcggaag
     1561 ttacccagcc ctttggactg ggcgatcttc tctttgattt cattttccat ttccagcgta
     1621 agattcggat cgctggtata gagaataaag cccatatgtg ccccattatt gtagtaacgg
     1681 cgtcggaaga tggttgcctc actgttgagt aacaccgaat ggatgccgcc gatatagtca
     1741 ggcaggccat acacctgctg gcgcgggtcg tacattttaa aaaagacgat gtcttccggt
     1801 tcatagataa gtgctggccc ttcctgcaaa acagcaaacg ccccgtcttt tcggcagcgc
     1861 agatacagcg acggcagcgg cagcaggtcg atcacttccc cgaatacgtt acgaattttc
     1921 aggatagcga cgtcaccaaa cagcaggtaa tcaaagacag cctgttcgac ctggtcaggc
     1981 gtcaggccgc cgccgatgta gccaccggca accatattgc gccgcgcata cagtacccca
     2041 ccgtgctggc cgttaaggtt cggcaactgg gccagcgcca ggcgatcaat cgggagtcgc
     2101 cagtggtcat actcattgtc ataccagata ttgtgataat cagtgccggt cgtcaggatg
     2161 ggttcgggtt cgccaaatgt gatcacgctt ccgcgccctg gcgtgaagga ttcaaccttg
     2221 ctgccggtca tggacctgaa ttttttatta ttacgctgtt tctttgtcat gctgctttcc
     2281 caaagtacca gcccgatggg cggtcatatt cgtgatcgat aggttcgtta attacggcgt
     2341 gcgagatagc gaagaaaaca tctgcatggc cggtcgcgtc tgaacgttcg gcaacaaacg
     2401 tcagcgcgtt gccgctgttg gttgtcgtgc gccggatagc cataaagctg gccggaattt
     2461 cgacgcgctc tttgttcgtt tcgtctacgg cgtcttttgc ccattcgatg cgcttacgct
     2521 cgacaacgtc gatcatcttc attaccagac ggtttttgct ttcgacgctg taaagaatgg
     2581 gtgtggcttc gcgcggtgca aacttgctga ccaggtcata aacgccctta ccaatgccgg
     2641 ttgtatcgat cccgatgtaa gtgatgttaa agcggcgcat aagctgcttt atctggtcgg
     2701 cctgccagct gaagttaaag ccccgccatt gccagacggc cagcacgcgg aagcgctcgc
     2761 cgtcctctat ggggggcgcg attaacacaa aggtggagtt gtcgccggat cgtgacgggt
     2821 caaagcctgc ccatacttcg cgattgccga agggccgcgc agcggtcaga tcaaagtcgc
     2881 cccatgtggc ccggtccact tcgcagccga caagcgcgga gaacttgaac accgcgtcct
     2941 tactgtcaac aaactggcac atgtagagca tggcgaacgc ggtcgggctg tatttgttgc
     3001 gcagccgttc aatatcgaca agcgcaccga ggccaccttc gatagcgtct tccatcgtta
     3061 tgatgtagcg ccagatctgg tccgggcaga gaataccctg gcgcatttcg ctttctgtcg
     3121 ggaacgccac acctttgcgt ttcgggtcgt ccccgcgcca ggcttcgcca gtccataccg
     3181 ggtaagcctg gtgcgttttc gcgctgggcg tcgaaaagta ggtcgtccgg tatttgttat
     3241 gcgttgccat tgcgctggca acttcgtgca ggcgcgtgaa tttcgggatc cagaaaacct
     3301 catcgccata caggtggccg ttaaagccct gcgcggtgct ggcgttcgtg gacaaaaagc
     3361 gcagtattgc gccgttgctg aggcggatat ttttacccgt cagcgtcacg ccgaaatggt
     3421 tctgggcgat ctggacgatg tattcacgga agatttcaga ctgggagcgg cttgcagaga
     3481 aaaagacctg gttatcaccg gtaatgacag catcttcgaa tgcctcccag gcgaaataat
     3541 aggtcatgcc gacctgtcgg cttttcagaa tgaagcgcca gtcttcgcct ttatgttcgc
     3601 ggcagtgcag ctggtactcg aagagatgtt cccgcgccca ggtgtcgagc atttccggtg
     3661 taataccgga aacgtcgttt ttcttatacc ggcgctttct ttcctctggt tccccgcctg
     3721 cgctgctgag gcagtaccct tcaccatcat aagccgcttt ctgggcctga atttctgcca
     3781 gcttttcggc gtgtttgttg cgctgcgcca tgagtttcac atggtgagca atcagatcgc
     3841 gcagttcttc cagttccagc gctgtttttt tctcgcggcg ggagagctgg tcgatacggc
     3901 gggcgatgac attttccacc gattcaacag gcagcagtga tgcccacttc ccgacatcag
     3961 cccagtggta aattgtacgc ggtggaatat tcagttcctg cgcaatatct ttcggcgtcc
     4021 agcttttcat ataaagcgtg cgggccgctt cttttaattc atcggaatat ttagccatgc
     4081 ggctattatg gcgggattat tttgcagaat tgataattaa atatcggtaa aaagtggcta
     4141 tgtatttata accgaataca taagaaataa agcggtcgcg ctgttttaat caattcgcaa
     4201 tactgaccac cacaaacgaa tcattgttat taaattcatt attaaaggtc agttatgccg
     4261 caatctcatt accgcacgga ttggctatgt attgccacat ctggaaaggc tgtggacggt
     4321 cgcaccattg aaccgcaatg gttgattgat gcggcagaaa cctacacccg caaaacctac
     4381 acggccatga tttggccgca ccatccgcaa tgcgatatca gcgaacgtga atttacctgc
     4441 aatctggggg aagtggacgc gctgaaagtg gaaacggaag gtgatgtcac gaagttatat
     4501 gcccagttaa tcccaaatca atttttaatt gatgccaatc ggcaggggca aaagttattt
     4561 acgtcagcag aatttgtcac tgattttgca ggcagtggtc gtgaatatct ttttgggctg
     4621 gctgtgacgg atattccggc aagtctggga acggaaaaac ttaaattcgt tttagccggt
     4681 gaagaaaagg acgccgaacg cgggagtctg gaaacattca gtttaggaaa attacagaca
     4741 agtaaaccgg ataaaaaaaa ttctttctgg tcgcgtttat tttcggccag taaagatttt
     4801 acgccaaccc cagagccaaa cactgacaag cccaccgagg gcgacggaga aaaaatggaa
     4861 gaattaaaag cgctcattca gcaaatgctg gatctgctta aaagcggtaa agacgccgca
     4921 acgggtgatg ctgacacggt tgatacccct gaacaggccg ctgatgtggt ggcagatgtt
     4981 gccgcccaga tcgctgatgc tgccgacgag gtggccgagc tggcgcagga cgttatcgaa
     5041 aacccggaag acgaagtcaa agcggaagaa ttcagcgccg ccaaagccaa cctggcaaaa
     5101 gtcatgaagt cattcaatgt gacgccagcg aagcgcccac gcgccagccg tcgccgtgac
     5161 ttttccgccc gtcgccagcc agctggcaac cagatggaca accttaccac gcagctgact
     5221 accgtcctga ctaagttgtc agcgatggaa aacggcaata cgcgccgccc tggcagtgcg
     5281 ccaggcggaa gcaaagaacc gtttgagttt gtttaacagc cattcttttc aggaataaaa
     5341 gattatgcaa ttaaccccaa aagcagagca gatgctgcgt aagtttgccg caggcctggc
     5401 gaaagctaac ggccaggtgg acacgtcgcg ctacttctcg ctgacaaatc cgaaagaaac
     5461 ccagctgcgc aatgccctgc tgcaaagttc tgagttcctg cgcctgctgc ccaatgtgct
     5521 ggatgtggac cagatcaccg gccaggtggt cagcaccggt aaaccgggta tttacaccgg
     5581 gcgtaaaaaa gatggtcgtt tctcccgcgc cctgggcgtg tccggtaacg agtacaagct
     5641 ggtagaaacg gattccggtt cgtatctgcc ttactccctg ctggttgtct gggcgaacgc
     5701 gggcagcgaa gaggagttct tccagcgtat tcaggcattc agcaacgaat ctttcgcgct
     5761 ggatatgctg cgcgtggcgt tcaacggaac gagtgttgca gaagatacag acccggaagc
     5821 caacccgaat ggcgaagacg tcaacatcgg ctggcacaaa atcgttaaag accgttcatc
     5881 tgagcagatt atttctgatg ccgtcactat cggcgcgtcg ggtgctgact ttattggtct
     5941 ggatgcggca gtcactgacc tggtgcacac ctgcatttat gagccattcc gcaatgaccc
     6001 gcgcctggtt gtgctggctt ccgctgacct tatcggcaac gacgccacca ccatgatgaa
     6061 taagattgat cgcccgactg agaaagtcgc cgcgcagctt attggccgcc agattgctgg
     6121 ccgtaccgtg tacaccccgc cgtttatgcc ggaggggcgc cttatcgtca ccacgctgga
     6181 caacctgcat atctataccc agcagggcac acgtaagcgt aaagcggaat ggaacgacga
     6241 ccgcaagcgc ttcgagaata actatctgcg catggaaggt tacggcgtcg agcatgacga
     6301 gctgtatgcg gcattcgaca aaatcaccct tgcgaccggc gaagttgcac cgggaggggg
     6361 cgcgtaaaaa tggccatgac cccgtgtcag cgacaccgag cacgcgtgaa agccacaaag
     6421 gcgctggata agtgcgaagc cctgacggca tcgccggtca gctttcacat tcaaatgctg
     6481 gagctggaaa gggatgttga acggcttcgc agtctgacgc gtgcagaacg catggacatg
     6541 aagcgcgacg ttcttttgcc gcgctggatg ccgaccgtcg aggcatatct cgccggtgat
     6601 gcccgctttg ccaatccggc cctggtttac tgcgtgatct ggctgttcga tacgggggaa
     6661 atgggcaagg cgctggactg ggctgacgtg gctatcagtg agagccaggc cacgccggaa
     6721 aacttcaaaa gcaacctgcc tgcctttgtg gccgacacgg tgctggagtg ggcgatcatg
     6781 caggcggaag ccggtcacag catcgaaccc tatttcagcc gcacgtttga aaacatccgc
     6841 gaaaagtggc gtttgcacga agacattaac gcgaagtggt tcaagttcgc cggtctttac
     6901 ctgctgcgcg acgagaaggg gcagccgcgt gccactgccg tggatgatgt gaacacgctg
     6961 gagcaggccg acgccctttt ggcccaggcg gcggcgtaca acaaaaacgc cggagttaag
     7021 accatgcgcg aaaaaatccg cgcccggatt aacggcctga cccagcttta acgactcccg
     7081 caagccggga cgggcgcggg ggaggcatca accatgcggt tgttggccgt ggaacccgtt
     7141 agcccgtttc tattgcaaaa ccgaggtgcg ccaatgagtg gcccaagttt cagtatcagc
     7201 ggcaagccgg tgacggtgac gccaacagcg atcaccaacg gcgtgacatt ctggcccgat
     7261 ctcgatctgg ccgagtttca gaaggtgcgc acgctacccg ccgatctgcc gccagaaacc
     7321 gcaggcgtgg ccctgctggc tgctattgcg gaagtaaacg acgcgctggc cgacgtggtg
     7381 acgtactgga acgcgaaagc ctgcgagcgg gctgcagatg taccgggtgc aaagatgggc
     7441 gacgaaaccc agttaacagc ccagtacaaa aaagcggtct acgcccgcgc aaaggccgat
     7501 ttgctggggg agttcgccac catcgggcgg cgtgaatcgc atccggggca ggaaagccag
     7561 gacacccgcg ccagcctgct ggccgaggcg gccaacgtga tgcgaaacat gctgcggcaa
     7621 ccacgcgtgg gggtgcatct gatatgagcc agcttgaaag cctgacggcg tttattacgg
     7681 caaatctgcc gcctgatgcc atgcagatgt tttccagttc aatggaggat tgcgagctgg
     7741 tacgcaacgc caaagcgctg ggaaacaacc agcgccggat cggagtgctg acttacaccg
     7801 cccgtttgtc gtgggatgac ttcccctacc gcaaatattc gccggggctg atttatgccc
     7861 tggtgctggc ctgggtggat gagttcgcca acgagctgcg cgacgaactg aagttagccg
     7921 atcccaccgt ggacccggag ttcgacgacg aagggtcatg cattctggat gtggttgtcc
     7981 cgctggttga tccgctggtc ctgcgtgaag tggaaaaagg gccgatccct ttcaagggca
     8041 agaaatggga catcgtaaac cccgaaatct gggaggcgtc gcaactggaa tttattgtcc
     8101 agcgtggtga cgcgtcgtga tccgtgggga gctgaaccag caacagctaa agcagatgcg
     8161 ggaaacgctg gcaaaagctg accttccccc gcgtaagcgc cagcgccttt tatggcgtat
     8221 tgcaaagctg ggcattgtcg cagcggcaaa acgtcaccag cgccagcagg cggccccgga
     8281 cggtacgccg tgggagccgc gcaagcgtgg caaagggaag atgttaaaag ggctgcccaa
     8341 gctgttggcc gtgcgcgaaa tgccggagat tcagggggta agaatttacc tcaagggcgg
     8401 gaactaccgg aacgggacga agcccatcgc ggcgggtctg gtcggcgcgg tccagcagga
     8461 cggcgcacgg atccagatga aagccagtaa cgccccgcgt aagccgcagg ctgacaagcc
     8521 agcgctaccg cgacaggcca agcgtctgcg ggcgctgggt tacaaaaccc gcaagggcaa
     8581 acgctgggtt aagccgtcca gcaagcaaat catggaaacc atgagcatgg cccaggcggg
     8641 attactgatt cgaaaactga aaggcacacc ctcaaaacgc acatggacca ttgatattcc
     8701 tgggcgcgtt tttctggggg tgagcaacga cgaatttaac caaattattg cgcggcaaat
     8761 gcaggcaatc ggcttcggct gggacgtcaa cgcgcagcaa atcagggggt aaaaatgacc
     8821 tggccgaatg tcaacgtcag tcagaaaaac cgcttcaacg gcacaacgaa cgacgtcgag
     8881 cgcgtcatcc tctttgtggg ttacggcgac actaacatcg ggaaaaccca gtcgctgaat
     8941 accggcagcg atctggataa agccctgggc gacaaagaca gcccgttaaa aaatatggtg
     9001 gccgcagcgg ccaataacgc cggtcagaac tggtttgctt acgtgcatgt gctggcagaa
     9061 ccagacaagg aagccgaggg ctataaacca gatgaagact ggatgaacgc ggtcaagatg
     9121 gcccagagcg tggcatccgt ggaaggggtt ttcctggtat ttgataccga cgaagtggca
     9181 accatcaacc gtgcaacgga aatgcgtatc accttgcagg ctaattatgg gcgatttatc
     9241 tggtttggcc ttgcgatagg cgggccgaaa cagggcgaag catgggccga ttatgtgacg
     9301 cgcctggcac aactccagga cggtattgcg tcaccgggtg tgcaactggt cccgcgtctg
     9361 tggggcaatg aacccggcgt cctggccggt cgcttgtgta accgttcggt gacggtggca
     9421 gacagccccg cccgcgttgc aaccggcgca gtcaccgcgc tggggcgtga caaactgccg
     9481 gttgacggga cgggagccga aattgatctg tccgtgttgc agtccctgca ggtgaaccgc
     9541 tacagcgtgc cgatgtggta tcacgactat gacggcatct actgggctga cggtcgcacc
     9601 ctggacgttg aaggcggcga ttatcaggtc attgaaaacg tgcgcgtggt tgataaagca
     9661 tcccgacgcg tccgtctgcg tgctatcccc aaaattgccg atcgttcact gaacagcaca
     9721 ccgggcagca ttgccgcgca tgaaacctat ttcggcaagc cgctgcgtga aatggcgatt
     9781 tcaacccaga tcaatggcgt cgaatttccg ggcgaagtga agccaccaaa ggacggtgac
     9841 atcaccatca cctggaccag tagcgaagcg gtacagattt accttgtggt tcgaccgtat
     9901 gagagcgcga aagaaatcag cgtcagcatc gaactggaca cctcactgga gagctaatca
     9961 atgactgaac gtattagcgg cggatcgttc gatgtgaact acgacagcat catgattcac
    10021 gtcgaaaacg ccaccgtcac cattacggat aacagcgccg ttgcgcagtc gcgtggcatc
    10081 ccgaacggcc acacgaaagg gtcagtttcg gcggatgtgg aagtcgaagt cgattcccag
    10141 agctttaaaa agtttaccgc cgttgcccgt gccgcaggtt cctggcgagc cattccggca
    10201 aaggactttt tgttctatgc caatgcgggg gatgacgaag aaaaaatcga ggtgtttggc
    10261 tgtgttccga cgctgtccga catcgtcaac atcaacccca acgaggccag caaaaccacg
    10321 aaaaaaatta aattcatggt gacaagcccg gactttgtcg cgattgacgg cgtgccgtac
    10381 ctgtcagccc gtgacactcg agatctgaaa ggctgacacg atgatgaacg gagaaacgtc
    10441 actgcttgaa aagctgttgc ttatcggggc cgtgatcggc ctggggcaac tgatggtcag
    10501 caatgagcga atcacaaccc gtctgctggt cgggcggatg attctgggat ctgcagtcgc
    10561 accgctggcc gcaatcccgc tgctgaaatt ccccgatatg ccggaactgg tcgtcattgg
    10621 gctggcctgc gccctgggca ttctgggaag tgcgtttatt gaggcggggc taaagcgctg
    10681 cctggacatg tatatcaagc gatgggggag caagcgcaat gaaactgagt gaaaaacagc
    10741 aactttttac ggtgatgatc gccagcctga ttcattttgc ccaggaaaaa ggctatcgcc
    10801 tgacgtttgg cgaagcgtac cgcacgccgg aacaggccgc gcttaacgca aaaaaaggga
    10861 gcggcattac taacagcctg catacccagc gccttgcggt ggattttaac ctgtttatta
    10921 acggcgaata ccagaccgac agcgccgcat atcgccccct gggcgaatac tgggaatcta
    10981 tcggcggatc gtggggtgga cgtttcagta agccggacgg gaaccatttc agtcttgagc
    11041 ataacggggt tcgctgatgc gcaatttgct gggtcttttg ctgattctgg cagctgcaat
    11101 gtcagcgggc tggcaggcgc atgactggca cgacgcaaag ctgaaactcg ctgccagtga
    11161 agcggcagaa caaacgcgcc agattgttgt tgaggtgaca cagcagtctg gtgaagcgct
    11221 ggaagcaaaa ctcgcggagc tgagggccaa tgaaattcat acggaacggg ttatccgcac
    11281 ggaaaccatt aaatcggttt ttagcaatgt ttgtgcttct gatgattacg tccggttgtt
    11341 caacgaaagt gcagatcaag ccgaacgaaa attatcagga aaaccagctg gcactttgcc
    11401 cggtcacgtt gccacgtctg gccggaccga ccggaagtga ctttgacgcg gcgctgaaag
    11461 cctaccggct gatgtatacc gactgcgccg cccgacataa cgccctggtg ggcatcattc
    11521 gacaacgtaa ggaattagca caatgagcaa atcgaaaaaa atcgccatga ccgtggcggg
    11581 cgtaaatctg agctttgagc cgaataaaac cgcgttcaac aacctgctta acgaaatgac
    11641 catgaccaat aaagttgccc caatggtgac gtatctgggc cgcattgttg atgccgagtg
    11701 taaagaggcg ctcaacaagc tgatggaaga ttatccgggc tgcgaaatgc agatcgtcga
    11761 gaaggttaac gaaatttact ccccaaaact tgagatcgaa gtaaaaaact gacggcgcgg
    11821 gtagcggcca ttcgcacgaa tgccctggag caataccttg ccttgcgccg ctattacctc
    11881 ccgcacgaag acgacgacga agaaagcatc gcccgcgccc tgtggctgga tgaatatttc
    11941 gcccagaccc gcgccagtaa gacggcggaa gggatagcaa tcgcatttaa cggaaactga
    12001 tatgagccac ctggatttta ccctgagcct gatcgataag ctgacgcggc cattaaagac
    12061 ggcccagtct tcgctgtctg gctttgctga aaaatcgcag gagtctttta caaaaatcgg
    12121 gattggtgcg gcggctgtct ggggcgtggc gcagtccatc gcgggcgtgg tgggtccggc
    12181 gtatgagatg aacgccgcgc ttgcagaagt gggttccaaa ggcgtagcag aggacgcgct
    12241 gaagcgtatg tccggcgaag ccatgcgatt cagtatgcgc tacggcaaag gggccgttga
    12301 tgtggtccgg tcaagctacg cgatgaaagg cgcaatggcg ggcctgtccg atctggacct
    12361 gccccgcgtt accatcgcgg ccaataccct ggccgcaggc gtcaaggcca gcggcgaaga
    12421 ggcaggcgaa tacatcggcg cgatggcgtc acgtttcaac gcggaattgt ccagtctggg
    12481 gcatgtgcgt tttgccgaag agctggcagg aaaaacggcg tacatggtgc aaaacttcgg
    12541 cgtgaaaatg cagaccatgc aggagcttat cgaggggacg aaaagcgccg gtgctgactt
    12601 tggcgtcagc ctggatgaac agttcgccgt actgggtacg ctttcgcgca cgctgggtac
    12661 tgaggccagc gggatctacg agcagttttt acgcagcgcc ccggctgccg ctgaaaagct
    12721 gggtatgagc tttgtcgatg ccaccggaaa aatgctgccg atgggcgaca ttctgcaaaa
    12781 actccagaac aaatacgggc agagcattga agggaacgtc aaggcacaac aggcgctgga
    12841 tgccgcgttc ggtggtggtg ctgacgttat caaaaagctg tacggccagc aggataaatt
    12901 aaaccgcagc atcaccgagc tgggccgaaa tgacgggatg aaacgcgccc aggaaatggc
    12961 cgaacgaatg gctgagccgt gggaacgtat caaagcgaca ttctttgcca ttcgcgtggc
    13021 gattggtaac acgctgttcc ctatcctgtc gccgctgatg aaccgtattg ccgacgtggg
    13081 gacaaaattt gcccgctggc tggatatgtt cccgaatatt gcccgctggc tgggttacat
    13141 caccctgggc gtgctgtcct tcgggttggc tggggcggcg gtcaatatcg tgatgggggt
    13201 ctttggcttc accatgacag ggctggccgc aattgcaaaa gtgctgggcg gggcatggaa
    13261 actcctgtta tggacgctca acctgttgcg tccgtccctg ctgacgacgc gcatcggtct
    13321 ggctgcattg tggatccagt caaaattact ggcgctgtgg acgggcgtct gccgcatcgc
    13381 gcttgctgca tggaatatcg cgttaaaggc cggagccatt gccatgcggg tttacggtgc
    13441 ggcgaccatg tttgccgggg cggcaatgca actcctgatg agtccgatca ctctgatcgt
    13501 tgccgggctg gcacttctgg ccgtgggggt ctggtatgtc atcacccact gggaagaact
    13561 ggcggcagca atcatggata cgtcggcttt tgcctgggtg atgtcggtcg ctgaacaggt
    13621 aggccaggtg tttgcgcagg tctggcagtc catcacagac ggctgggccg tggtggttga
    13681 tttctttgcc ggtctttccc cgcttgccac ctttgaaggg ttcgcacaaa ccatcggcgg
    13741 ggtattcagc aaactttttg acgtcctcaa aaataccttt gcgtctacct ataactggat
    13801 tgtcgagaag ttaaacaaga tccccggcgt aaacatcgac ctgaaaaccg tttcgccacc
    13861 ggcagcggct gccgttccgg caaatgcggt cattcctgac agtgctgcag gttcatcgaa
    13921 gctaaacagc ccgtccgtgc tgacggggaa ccgaattaat gcaggcatcc cacgcggcgg
    13981 cctgatgagt caggttaaaa acgacagcaa aaccgctgtt gataaccgta aaacgtgggg
    14041 cgatacctac atcaacgccc ccaatggaat caccccggcc cagctggctg aatggcagga
    14101 gcttaacgca ggatgagtac cgaaccgtta tacatcgacc ttttgatcac tgacggcgat
    14161 ttcacgctgg acagcggcaa cgagccgcgc cgttgcgata accgcgacag catcacccag
    14221 gacattattc acagcattct ggaaagcggt atcaccaccc gcctgatcgg tgaacgcagc
    14281 ccgacaatgc gcggtgacgt gctgacgcaa ctgtccttac tggtggaaag cgacgaacgt
    14341 ctggtcccag gaaccatagt gatcaccgaa gaaacccttt cgaggttgta tatcacggcg
    14401 gaaacctacg atttcggccc tgtcagtaca gaggttaact atgactgaga aacccgacgt
    14461 tgatttcgaa aaggtactga atgacagcgg gatgcccgcg acagaggccg aaattacggc
    14521 ggcatttaaa gccaccgtgc aggcggaagg gttcgtcaca aacacgtcga gaatgtcacc
    14581 tttctggcgg ctgatttcga agattgtcac cacgccggtg ttatggctgc gtgcggcgct
    14641 gatcgatgtg gttctgcgca atatgtttgt tgcgactgcc accggtccca tgctgcgcct
    14701 gctggcctgg gcggttcata tcgagcctaa accggccagt gctgccgctg gcgtgctgcg
    14761 attcttcaag ctgaatgcgg cggatgtggt cgtcgtgcct gccggaacac tggtgcaaac
    14821 agagcgcatt aacggcgtgg tttacgtgct ggccgtgaat gaagacgtga cactgcctgc
    14881 cggggttgaa agcgggctgg ttcccgtcac ggcgaccggc accggcagcg gctataacct
    14941 tgcgccaggc tattaccgga tcttacctgt tgcagtagct ggaatcgcca gcgcggtcaa
    15001 tgaggacgaa tggctgatta cgccaggggc taacgaggaa agcgacgacg agctgcgcga
    15061 ccgcacccgc aaccagttta atctggtggg gaattaccac tctgacgcta tctaccgcag
    15121 catgattgcc agcgtgctgg gcctgagcat tgatcgcatc tactttttgc acgatgcccc
    15181 gcgtgggccg ggtacggcaa atgcttatct gttactggac agcggcgaaa tatcacagcc
    15241 ctttattgat gcggttaacg attatgtgaa tacccagggc caccacggac acggtgatga
    15301 tctgcagtgt tatgccatgc cggaaaccag tcacaccctg gcggttactg tctatgtcaa
    15361 aagcgtggaa aacatggaag cggaagacct gagcgcgtta aaaaccggta ttaccgacct
    15421 gattcgttgc gcgtttcgcg agaacgccaa ttacgacgtt aaaaagacgc agccctattc
    15481 gcgctattcc ttttcgaatc tgggccgcga gatccacaag gcttttccgg ttgtcgattc
    15541 actgcatttt tcactaacgg atattgtcag cgaactgtcg gtcccgcgcc tgtcagggtt
    15601 aacggtggag attgaaaatg actgagtttt cgaagttgct ttccggtctg aaattgccgt
    15661 cgtggctgaa caaaggcgac cccgccaggc tgttgcgtgg cagcgtgaag ttctggtcgc
    15721 aggtgtacgg gtggatcacc tggccgttaa agcagtttga cccgctggtt tgccctgagc
    15781 cgctgttgaa cctgattgcc tgggagcgcg acatcgatcg gtttaagggg gagccgctcg
    15841 acatcttccg caagcgggtg agttacgcat ttatcaatgc gcagcaggcc ggagaggtgg
    15901 cgggctttat tgccattttt gagcgactgg ggattggtta cgttgaatta ctggaacggc
    15961 aggacggact cgactgggac gtgattgtcg ttcgagtgac aagcagccag gttgcggaaa
    16021 atggcgatct cctgctggaa atcattcgca aatatgggcg cacatgccgc cgttaccagt
    16081 ttgaagtaat cgacaccctg ccactgaata tcaatattgg ctggtatcag ggggaatata
    16141 tttgctggcc tgccaccctg ggcgatgtga ataaccagtc agaagcaaca tatagcgcaa
    16201 gtttgaagta gagggaatat taatgtcaca ggccgtcatt acaaaagcat ttgcagagtg
    16261 gaaagcccag caggcaatta ataaccagcc cgtcacgctg gatgagttta tttttgctta
    16321 tattccgggg ctggatgctg acaagccgat taataatact gaaacaacgc cagcggaaga
    16381 taaaatagtt tgtcgtcagg cggtgaataa agccggtgtt gtgaatgaaa actctgtcgt
    16441 ttattccgtt accctggggg cggatgtggg cgattttgat ttcaactgga tcgggctggc
    16501 aaataaggca acgggtacac tggcgatgat tattcacgcc ccgacccaac gaaaaattaa
    16561 aaacgcagac ggtcagcagg gaaacgttct tgttcgttcc atgctgatgg aatacagcgg
    16621 agccagggaa gcgaccgaaa ttaacactcc ggcagagaca tggcagattg attttactgc
    16681 ccgactggtg ggaatggatg aacgccagcg ccgggaaaat atcgatctgt atggcgcagc
    16741 ggcatttttt gattcgggct atctggtcgc aaagtccggc aatcagtttt ttgtcacaaa
    16801 gggggcggga tatgtcgccg gattgcgtgc cgaattgccc gcaaacttca atatcacagt
    16861 atccgcgaaa ccgacaaaaa tctggcttga tgtgagctgg accgggacgt taacaagcga
    16921 atgggctgta cagagcaaaa ttactgttgc tgcagatctt gccgattatg tgctgggcgg
    16981 tgtgcagcat tatgtctttg cggtggcgag tattgatgct gccggaaata tcactgacct
    17041 gcgcccgaaa ggcacgctaa atgaccaggc ggccagcgat gcgctgaaaa agcatgaaca
    17101 atcccgaaat caccctgatg catcaaccag tgaaaagggt tttgtgcggt taagcagtga
    17161 aacgaacagt gattccgaag cgatggccgt cacgccaaaa gcattaaaag cggtgaatga
    17221 gaatgcaaat ggccgcgttc cggcatcacg aaaagtgaac ggccatgccc tgaatggaga
    17281 tatcaatgtc acttcacggg atatttttga cggccaggtt atagcgattg gtgcaaataa
    17341 gaatctggat gattaccagg taccggggct ttattttcag gaagcgaaca acaataccag
    17401 tgcagcaatg aattacccgg agaatagcgc gggttctctg atggtactga gaggtgccgg
    17461 agtcactcag gtttatcgtg tgtacaacag ctcgcgcagt tattcgcgca gcaagtattc
    17521 aacgctggca tggacgccgt ggatgccaga agattcttac cctgtcggcg cacctatccc
    17581 ctggccatcg gatgttaccc cgacagggta cgccttaatg caggggcagc cctttgataa
    17641 agcggtctat ccattgctag cgattgccta tcctgcgggg attatcccgg acatgcgagg
    17701 ccagacgatt aagggtaaac cgaacggtcg cgcggtactc tcgtatgaac aggatggtgt
    17761 tatatcgcat acccacggag ccagtatttc cgataccgat ttggggacga aatacaccag
    17821 ctcttttgat tatggttcaa aaccaacaac cagttttgac tacggcaata aatcctccac
    17881 tgagggtggg tggcacgcac ataactttcg ttattgcgca acgtctgcat accgggatac
    17941 ccccggtcag gggctgggga tgcattcgtc taatgtttca tgggcggcgg gagatcgcat
    18001 tgagggaagc ggtaatcatg ctcatgtgac atggatcggc cctcatgatc actgggtggg
    18061 tattggtgcg cataaccatt atgtggttat gggctatcac ggacatacag cgaccgttca
    18121 tgccgcagga aatgcggaaa ataccgttaa aaatattgcg tttaactaca ttgtgaggct
    18181 tgcctgatga cttttgaaat gaccggagaa aaccggacaa ttaccatcta taacctgcgt
    18241 gctgatacaa atgaatttat cgggaaaagt gatgggttta tccctgctaa taccggtttg
    18301 cctgctaaca gtaccaatat tgcgccaccg ccgatgaaag ccggttttgt cgctgtattt
    18361 aattctgcgt cagaaaaatg gtcacttgtt gaagaccatc gcgggaaaat tgtttacgac
    18421 attctcaccg ggaaatccat cacgattgat gaattaggtc agttacctga cgacgttgtt
    18481 tccgttgcgc cggaaggcca ttttgttaaa tggaatggta aaaaatgggt gcatgatgct
    18541 gacgcagaaa aaacggcaca gattacacag gctacacagc aaaaagacag tcttctggcg
    18601 ctggctgcat caaaaattgc cccattacag gatgctgttg atctggatat tgcaacggaa
    18661 gaggaaacag cgcttttgct ggcgtggaaa aaatacaggg ttttgattaa tcgtattaag
    18721 ccagaagatg cgccagatat tgactggccg gaggttccgg gcgatgtggc gtgagtcggt
    18781 tataaagatt gctgatgata tgggggcgct ggcctgttca attgtgccag cgcatccctg
    18841 ggtttacggt ctgggacaga acaccgattc aggcggttat ctcagtccgg ccaatgcgct
    18901 gggatacctt gctaaaaagc tgttatccgg tggcggtagc ggtagcggtg atgtcatcgt
    18961 catgatggtg gcggagaata cccacgatgc ttttatgcag ggactgaata aactgtccac
    19021 cgtatttccg gccccggtat ttacgcaggt aagccgtatg gccgcagccg ccgcagaact
    19081 cagcacggta aaaatgcagt tgccggttaa agccgatgta ttgccagcca gtgcgccgtt
    19141 atcagtctca accaaccggc tggcgctgaa tgcccagcgt gttgccgccg cgcagctggc
    19201 cgccgcagtc agtaccacca caacagatct aaaaaaccag gtgacgggat ttattcagga
    19261 acgggccggt ttgctgtcct cgctcagcca gggactggac gacctgaaag ccgccagtgc
    19321 gaatattttt gcattcagtt acagcgggag ttatgccgtt gctgccgcag aattgctgaa
    19381 aggcatcccg caaacaacgg cagtgcatac cgccgcgatg atgtttatcg gggattcgtt
    19441 atctgactta gggaagatgc tacatgagcc agaccgcatt actcgcgctt gatggtgaag
    19501 ggatcgccat gcagaacatg ctggtttcac cttccatgca gtttcaggaa aaggaccagt
    19561 cgggccagac atcgagcacg gccaatgctg aacagggtat caaggccaaa gagctgcgcg
    19621 tatcgggtct ggtgacattc gacgacgaag ccgtcttaca gcggcttttc cagctggcat
    19681 ccgcgaccga agccagcggc gcactgaaaa agtaccgcgt cgccaatgcg acggcgacgg
    19741 ctatcaacct tcgtgaagcc acgtttaccg gtcagattga tgccgtaccg caggaggatc
    19801 gccttgcctg gcaggtaagt ttcaccctgc gtgaaaaagg cagcgtcccg gaaaaacgac
    19861 aggcccgaaa aggcaacgcg acggccagca ccaagcaaac aggggcaaag ggcgcgggtc
    19921 cggctgccgg agctgatgag ccagccgaca aaatgagctg gtttgaagaa aaggtcttaa
    19981 agccggtcaa cgatgcgctg gggtaattaa acgatgaaac caattaaacg cctgtacctt
    20041 tcctctgatc cggtccatct gattgactgc aatatcgtgc tggagctgaa cgcgtgcggt
    20101 cgggggttta ttacggcggg gacagagaca gattacaccg gcaaaatggt gcgtatcgat
    20161 gttggttatg atggtctggt cctgcgctgg tttaccgggt acgtcgaacg gtcacagcct
    20221 gctgataatg gaacatgccg gttgttcgtg cgtgagctgg tcggcatctt tgataaattg
    20281 tggccgtgtt ctttccagca tccaacgttg cgccagatta ctgactggat aagtgagcaa
    20341 agcgggctga ccgtcacaac gccggtcggc gctgcttatg cagataaacc gatcccccac
    20401 tttacgcaca gcggcacggg ctatcagctt tttgccagtc tgggccgtgc attttcagtg
    20461 acggattatc tttggtatca gttgccggac ggggatgtct tcgtcggcgc tgcggagcat
    20521 agtctttttg cgggaaaacc agtggagatc ccgcacgaat ttagccagga atcggcaggc
    20581 ggaaattcaa tggttgtgcc aatgattcag agcctgcgcc cgggtgcgga ggtaaacggc
    20641 cagcggctga accaggtccg gctaaataac gatgacatgg caattacctg gcagccccgc
    20701 aacaaagcca acggccagcc attgcaaaaa tcacccattc agcggcagat tgaaaacgca
    20761 ttcccggagc tggcaagcgg cctgcatctt ccaagattcg ctagggtgga agcgccaagc
    20821 gaggatgttt caggggggga tattgccgat ccattccgcc cacgctatgc cgtggatctc
    20881 cagctgcttg acgaagacgg caagccagcc gcaaatacgc cgatctattc tgccgttcca
    20941 ctacctgtgc caatggcggg cagcgagtca ggaatgtttc agtttccgcc ccctggcacg
    21001 ctggttgaag ttgggttcac tgaggggcgg caggataagc cctttgtgcg tcagattatg
    21061 gcggagggtc ataacctgcc agcggttaaa cccggtgagc agttgcagca acagcgcgat
    21121 ggtgtatcgc agcgcgtgac ggttgccgga gactgggaac gccagacgga tcagacaatc
    21181 cgcgaaaact ccatgactcg cgaagtcacc accgacgaag agatccgcaa agtggttgcc
    21241 cgtgaaacta cggtccaggc aacagataaa acaaccgtgc ttggcacggc cacacttctg
    21301 gccggggcgg tcgttcatat cagcgagggg gattacagcg tcggcacatc cggcaacctg
    21361 acagtaacct gcagcaagga caattccgtc agtgttggcc ggaacgtgaa acgggatgtc
    21421 gcgggcaatg ttacagacga cgtgaaaggg gatgtcacgt caaacgtcag cggcgcactg
    21481 actgaaaaaa tcagcggcat tcgccgaagt gtggcccagg cgcaacaact gattgccccg
    21541 gtggtaaagc tgggaagcga agagattaac gtcctgacac tgctcaccga caccctggac
    21601 gtggtgaggg agctggcaga gactgccgca tcacatactc accccaatac gggggccagt
    21661 gggcaggcgg cgcagttcac cgcaacggcc aataaaaccg gcacattgaa aagcaaatac
    21721 ggccccctga tagcctgaca aaaaagcggc ataaccgcac acctcaccag acaccacaga
    21781 acgcgccaca gcaggcgcaa agattaaagg tcgccaccgt gcggcctttc tttcgttcgt
    21841 tcaacagcgg cccacagcgt aagcgacagc aggcaaacgg aagcggatcc aggacggaaa
    21901 cggcgctaca ccgcacccgc ctgcgcagtt tggatcataa aaattttgca aaagaaattt
    21961 tgtgcaaagc accccgccag cctgcgccgc tgctgggctt ttgcatcctg cgggcgttgc
    22021 actctgcgca aagatttgca gcactttgca aaagtcatcg cgccgccagc tactaactga
    22081 ctggataaca tgatgttttt aaaaggatcg ttttggtttc cgtgacgatc aaaatgatta
    22141 ggtggtatcc gatggttttc gggggcggat atcgtgaagc cttgtgcggt gagggctggc
    22201 ggctagtttg ctttgatttg ggttttgcaa aatgatgcac gaagttttga taaaaggatc
    22261 tctagctaag ggggagggga acgtataaaa acccccgccc tctgggtgat attttgttct
    22321 atttatagaa gtttacttac tgaaatcagt ttgggagatt taatgccaat ctcacataat
    22381 gttgtatgat gtgcttcacg ctcagtttcc tgataatagg tggctatcca ttccgtattt
    22441 tcactaacaa tgctatgtat aaaagaaaag tagggaacat ctacagatga taacgaatgg
    22501 ccgatgatga tgatttcgtc tacgttgctg agatttttaa aaaatttagc gctgtcagca
    22561 atgacttttt cagtattctt aaaagaacaa gtgaagtatt tattaatagt ctgctttccc
    22621 atttcataag agtgatcgta attatcagcc atacactgac gccactcttc aagttcttca
    22681 tcggttgcat tttcgggcgg gactgcttcc ttttcttcaa agttgatagg gtcaatacca
    22741 tgacctaaaa tcaactgttg atctgatgat gcttttccat ggatatataa aatttgtcta
    22801 tcatcaatac catagtattt ctgaagagtc tcagtataat taaaactgat aaagatagag
    22861 tcagaatcga tacgcaatct tttatttaaa ttaagttcgg ggtagttaac ctgcaatata
    22921 aatgacttga attgtgttaa aagcccttcg gttaaatttt ttagtatacg ttccatttca
    22981 atgcttaatg agccccagtc cttgtcacga aaatcagggc tgctaatttg gggtaaaaga
    23041 tagcaaaact cttcgagcac tgactctgta tccagacccg ctaagctgtt ttcgaaatca
    23101 gaccaaagaa aatgttttga cttatcaact gcggaaagtt tagggggtaa gtcagtaaat
    23161 cccataaaat caaccaagtg atcgtaaatg tcttggtctt tcttccgaag ataatcccca
    23221 aatgagaaat agctcgtgtc aagttcgtga tgcagatcaa acccattccc gatgatgtat
    23281 agcttcatgc ttccaactcc ataacagtat tggcctttaa ggttgcgata actttcaagt
    23341 attagcgtgt ttgcctttga agaaaacccc gctttgtgga cggggtttgt ttgatgtggt
    23401 caatgtgtgg acattgtaag aaataaatcc atttatttca gtagattaca cgcaaaaaat
    23461 aagcccgtgt aagggagatt acacaggcta aggaggtggt tcctggtaca gctagcattt
    23521 tatgggttat gtttttcagc gaaacggatg ataaccttaa taaatgcagc tgtatgtgat
    23581 cggtttctaa gaattttcca tccgggaaaa ataatcgaaa ttaatcactt accgtgggga
    23641 ttacgcgtgg tttccccgga gaaattacgc atcagcagcg cgtaattgag ctcaagatcc
    23701 tgcgggaccg ggagccacac agtataacca tcgcctggtg ctatcggcat agcttcgcct
    23761 ttggcgtttt ccatgtgctc aagggtaaaa ttaatgttgc cttgcggcgt catcagctca
    23821 aggctgtcgc caacggagaa tttatttttc accgctaccg ccgcgaggtc ccccttgcgc
    23881 tcaccggtaa actcaccaac aaactgctgg cggtcagaaa ctgaataacc gtattcgtag
    23941 ttctgataat cgtcgtgagt atgacgacgc aggaaacctt cggtatagcc acgatgcgcc
    24001 agaccttcca gagtttccag caggctggta tcgaacggtt ttcccgcagc ggcgtcatcg
    24061 atagctttgc ggtaaacctg tgcggtgcgt gcacaatagt agaaagattt ggtacgacct
    24121 tcgattttca gcgaatgcac gcccattttg gtcaggcgtt ctacatgggc gatggcgcgc
    24181 agatctttcg agttcatgat gtaagtgccg tgctcatctt caaacgcggt catatactcg
    24241 cccggacgct gggcctcttc gatcataaac actttgtcgg ttggtgcgcc gatacccagc
    24301 gtcggctcaa cattttgcac cggaatcggc tcgtacttgt gtacgatgtt gccaacatca
    24361 tcttctttcc cttcctggac gttgtactcc cagcggcagg cgttggtgca ggtgccctgg
    24421 ttcgggtcgc gcttgttgat atagccagag agcaggcagc gaccggagta ggccatgcac
    24481 agcgcgccgt gaacgaagat ctcgatctcc atatccggca cctgattgcg gatctcttca
    24541 atctcttcca gcgacagctc gcgagagagg atcacgcggg tcaggcccat ttgctgccag
    24601 aatttcaccg tcgcccagtt cacggcgtta gcctgcaccg aaaggtggat cggcatttca
    24661 gggaagtgct cacgcaccag cataatcagc cctggatcgg acataatcag cgcatccggc
    24721 cccatttcca ccaccggttt caggtcacgg ataaaggttt tcagcttggc gttgtgcggt
    24781 gcaatgttga ccacgacata aaactttttc cccagcgcgt gggcttcatt gatgccgagc
    24841 tgaagatttt cgtggttgaa ttcgttgttg cgcacacgca gggaataacg cggctggccc
    24901 gcataaacag catctgcgcc ataagcgaaa gcgtaacgca tatttttcag cgttcccgcc
    24961 ggggaaagga gttccggttt aaacataatt ctctcgttct gatgacaggt cagatccgct
    25021 tcacctgatg aagcggttag gggagtgccc ccactttaag ggcgggcatt gtagcgcaat
    25081 cggcgggttt agctccagtg taaatgtctg gtggcgtcct ggttttggtt aaggatacga
    25141 atgacgataa tttcccctgg tgattgcagg aaataaatga cgtggcgttc aaaaggaaga
    25201 acaaaaatac cttcgcctaa ttcaggtctg ggcgtaccta tattattgtt actcagaatc
    25261 tggagaacgt ctgaaagatg ttccacatat ctgtcggctt gtggttcgcc gaaatggtga
    25321 tagctgtaat accagatgcc ttctaaatcc tcattggctt ttggcatgag tttaataata
    25381 cgcacattat ttccttatcc ctgctttcac cttccgtaag aacgcgtcct tttcccacgg
    25441 ctgagcttca ccactactca acccttctgc gagcatgtca cgtaacgctt gcaggcgaga
    25501 ctctgcttgc ttttctcgaa gtaatcgcag tgactcacgg atcacttcgc tttgggtgcg
    25561 atagtcgccg gattcaatta aggactcgat aaattcacgc aactcatcgc cgagatcaac
    25621 cgtcatcgtt ctggccattt tacgcccgcc tgtaagtaaa aatcttacat cagtgtatgt
    25681 cataaaccgg atagcgtcac gaaagtatta gaagatattt tggcacatga acatgttcag
    25741 gaggataagt atgggatggt aaacaaagaa agcacaacga gtgctcgtca gtgcccacta
    25801 ttttaatggc ggcggttact cttaattatt aataactaag cgttatttgg atataaagcc
    25861 ggacgccaac aacccacgcc cggcatcgta attacgtatt gtctttcacc gtctggcttg
    25921 tgccattggc tttaacggag gcaattccgg tttcacgaga ttgcgcggtg gcgtacatct
    25981 ggctggagcc gataatttga tgattagcgg ctttcagatt gaaatagaat ttgccgttac
    26041 ttgccgtttt tttctcatag cgttcttctt gcgggctgtt gctacgcacc gacgcgatgc
    26101 ccttttccgc agaggctttt gaggtataca gctcgctggt gaggatagtc tcaccattgc
    26161 ccgcttttag cacaaaccgg aactgattat cactgctctc actgagttca aaccaaccag
    26221 ccataatgac tccttgattg aaattgtgta tcgaaaacag catctaaagg tgctgtttac
    26281 cgattaaagt atgagcgatt ttctgatgcc tgccagggcg gagagataat gtcagtttgc
    26341 tgaccatgcg tgggataatg ttgccggatc gggtctgaac gccatctccg gctaacaaaa
    26401 taatgtcgct aaaactaaac gatgcggcag gcgtcggctt cccagcggta accgacgccg
    26461 taaacggcgc ggataaatga ctgttcggcg tcgagagatt ccagcttgcg gcgcaggttt
    26521 ttaatgtggc tgtcaatggt gcggtcggtt actacgcggt agtcgtcata aagatgattg
    26581 agcaattgct cgcgggagaa cacttttcct ggttcatgag agagcgtttt caacagacga
    26641 aattccgcag gtgtcaggtc aagcatttta ccgcgccatg aagcctgaaa acgaccttcg
    26701 tcgataatca acgggctttc agcatcctgt tgctgcaact cgcgctgcgg tttgcaacgg
    26761 cgcaaaatgg ttttgacgcg cgctaccact tcccgtgggc tgtacggctt acagatataa
    26821 tcatctgcgc caatctccag ccccagcagg cgatcgatct cttcgatttt tgccgtcacc
    26881 atcacgatcg gaatgtcaga aaaacgacga atttcccggc acagcgtcag gccatcggtg
    26941 ccagggagca tcagatctaa caggatcaga tccggtggtg tctggcgcac atacggcagt
    27001 acctgatcgc cgtggctgat aagcgtcggc gcatagctcg cagcacgcag ataatcaatg
    27061 agcaactgcc ccagcttcgg ttcatcttcc acgatcaaaa tacgcggtgt gttttcgtcg
    27121 attggtaact cggtcatact tctctctgta aatcccgttc cagcggtaac tctactgtaa
    27181 tgcttacccc gccaaaaggc gaatgggcag caataatgcg accattatgt gcttcaacaa
    27241 tgttcaggca aatcgccagc cccagcccgg aaccgccgct ggcacggttg cgggaacctt
    27301 cggtgcgata aaaacgttca aacaattttt gtagctgatc gtcactgaca cctggcgcac
    27361 tgtcggcaaa ggtcaggcgc accgttttgt cgcgctgccc ggcagagatt tgcaggctgc
    27421 cgccgctgtc agtgtagcgc aggctgtttt ccagtaagtt attgaataac tgcattaaac
    27481 ggtcgcgatc gccaaatacg gtaatactgt ctggcaggga aaattgcagt ttcaggccac
    27541 gactggcgaa tcgttcgcga aatgcgccgc ccgccacttc cagcagtggg atcaaatcta
    27601 ccggtgcttt ttgataggcg agagcgcctt catcagacat cgacaactga tggagatcgt
    27661 caaccagttt ggtcagtgta ccgacctccg cctgtaaaga cgccaccgtc tccggcgtga
    27721 atttacgcac gccatcctga atggcttcca gttcaccgcg cagcaccgct aatggcgtac
    27781 gcagttcgtg agaaatatcg gccataaaat cgcgccgcat ttgctggttt ttctccagtg
    27841 tgctggcaag ctggttgaag tcttgcgcca gtttgcccag ttcatcttca ctggtgggcg
    27901 ttacgcgggt agtgaaatcg cccgccgcca gtttgtgcgt gccatcgaca agtcgtttta
    27961 ccggtgccag taaaccgcgc gccagcagaa aggtggcgag cgccgcgagt aacgttgcca
    28021 gagcgacaat caaccagctg gtttgccgct gttgtttatc gaaattgata tcagtattgc
    28081 gcgttaaccg ctcaacgggg gaggcgatca ccgcgccaac ttccgcaccg ttgaccagaa
    28141 tgggtcgccg tgtaccgtca ggtggaatcg gcgctcgcgg accaaccagc actttgttgt
    28201 tttgatcaac cacccagaac tgggtacgcc agccgtgcgg tggcataccc gggccgggtt
    28261 tatcttccga attatcgtgt tcaaatgaac gcaggatctg aaagacaaag cgatcattgt
    28321 tgcgcaggaa gcgccagttg ccatgctgcg catactgctc gccaagcgca tcacttaaca
    28381 gttgtaatcg ctgttcatta ccatgcttga tgtaatcaat aaagccacgc tcaaaactga
    28441 tacgcaccgc ccagtgcata ctgatcagca agacaatgca ggtggcgaaa atcgccagaa
    28501 acagtttgcc ggtaataccg ggtcgccaga acttcattgc gcgctccttt ttcgccgcga
    28561 aatagctaca ttttgatgcg tatcgttcgg cactctggca aagatgaacg ccggaagggc
    28621 gatgatcaac gccatgctaa gccaggtgta cataaagacg gtttgtgtgg tgccgctgtc
    28681 gacgctgaca tgctgtgaac caaaaagtcc cagcaacagc ccggcgatag tgacgccgat
    28741 actcatcgac aattgcataa tcatcgacag caggctgttg ccgctgctcg ccagattgtc
    28801 cgggagatct ttcagcgtca gggtgttcat ggaggagaaa cgcgtcgagt tgaccatccc
    28861 ttgtaaaaac aggacgaacg gcaaaacgta gtaccagccc agcagggcgg tagtcataaa
    28921 caacagggtg accagcgaca gacccagcgt ggtcgctacc agtacccgac gataaccaaa
    28981 gcgattcacc acctgtacca caattcgctt cattcccatg ctgccaagca ccatcgggat
    29041 catcatcagt ccggcatgaa acggtgagaa accgaggcca atttgcagga aaaccggtgt
    29101 cataaagggc aacatgccac tgccaatacg tccggcaaag ctccccgcca ggcccagcga
    29161 aaaggtacga gtgcggaaca gtttcagact gaaaagagcg cggttgttat ttctggcgtg
    29221 cagcaaataa agcaccagtg ctaccacgcc aactgcgacc aggccagcaa tcgtcagcgg
    29281 cgataaacct gtacctttac tgccgtccag cgccagggtt aataccgcca tgccaaccgc
    29341 cagcaataaa aagccggaga gatcgaagcg ccgcgtctgc atggtatagt tcggcattaa
    29401 catcaatgtg gcgatcgcac cgataatccc caccggaatg ttgatcaaaa agatccagtg
    29461 ccacgacgcg tactccacca gcagaccgcc gagcgccgga ccgagcagcg gaccgacctg
    29521 accgggtaac gtgacaaagg tcatcgccgc catatattgc tcgcgcggta cgattttcat
    29581 caccgtcaat ctgccgaccg gcaccatcat cgcgccgcca acgccctgta acgcgcgtgc
    29641 cagcaacagt tcgttcagcg tgccggaaag cgcgcaaaac agtgaaccga gagtaaacag
    29701 cacgatggcg gtaaagaaaa tattgcgcac gccgactttg tccgccagcc agccgctggc
    29761 gggcagcatc accgccacgg tcagcacata agagacaatg accatgtgca tatgcaacgg
    29821 actttccccg aggctttgcg ccattgaggg aagggcggtg tttacgatgg tggtgtccag
    29881 cgactgcata aagaagccga aagccacaat ccacaattgc cagcgggtgc tgtcgggaag
    29941 atctgtcatt tactcggtta ccgtttgttt gggtttacgc gaaaaacgca gccgcagacg
    30001 gtcgaaaaag agatacacca ccggcgtggt atacagcgtc agaagctggc tcattaccag
    30061 accgccgaca atggtgatcc ccaggggttg ccgcagctcc gagccgtcac cgcccgacaa
    30121 caccagcggc agcgcgccaa acagcgccgc cagggtagtc atcataatcg ggcgaaaacg
    30181 cagcagacag gcctggaaaa tagcttcctg cggcgtcagg ttaccgtgcc gttgggcttc
    30241 aagcgcaaaa tcgaccatca taatggcgtt tttcttcacg atgccgatta atagcatgat
    30301 ccctatcagg gcgattaggc tgaacggggc attgaacagc tccagcgcca gcagcgctcc
    30361 aacacccgcc gagggcaggg tggagagaat cgtcagcggg tgcacataac tctcgtaaag
    30421 gatacccagc acgatataca ccgtggcgat ggcggcgata atcaggatca cctgtgagtt
    30481 catcgtctcc tggaacacct gcgctgttcc ggcaaaactg ccgcgcaccg tcgaaggcac
    30541 accaagctgg gtcattgcgc gatcgatcgc cgcactggcg tccgagagcg attttccggt
    30601 cggcaggtta aacgaaatgg tcgaggccgc cgataatccc tgatgattca ccgatagtgg
    30661 ggcattcgcc ggttgccatt tagcgaaata cgacagcggg atcgctttgc cttcgttatt
    30721 gataacgaac attttttcca gcgcactgat gtcctgggta tagcgcggat ccacttccat
    30781 caccacttta tactggttca tcggctggta aatggtcgag atttgccgct gaccgaaggc
    30841 gttatttaac agactgttgg cggcttgtac gtcgattccc agccgtgcca tggtgtcacg
    30901 gtcgtaaacc agattcatct ccgcgccgtt atcctgctga tcggagttca cgtccgccag
    30961 ttccggcaac gtcgccagtt ttttgcggat tttcggctcc cattcgcgca gtgccgccag
    31021 gtcgtcggat aacaacgtgt actggtagct ggcgttcgac tgacgcccac caacgcgaat
    31081 atcctgtacc gccatcagga acagattcgc ccccggttct ttcgccagtt ttacgcgcag
    31141 acggtcgata atttgctgcg ccgtttcgct gcgttcgtcg cgtggcttga gggtgataaa
    31201 catcatcccg ctgttcactc gcgaaccgcc tgtaaagccg gtgacattat ccactgccgg
    31261 atcgtcacgg ataattttca tgaaatcctg caacttaccg cgcatcgcct gaaacgaaat
    31321 actctgatcc gcctgaatac cgcccatcaa cacgcctgtg tcctgctccg ggaagaaggt
    31381 tttcgggatc gagatataca gccagatatt cagcgcaatg gtgccaagca gcaccacgcc
    31441 caccagacgg gtatgattga gcacccattt cagtgacttg ccgtagcctt gttgcagggc
    31501 taccaacatg cgaccaaaac cacgcattcg cttttgctcg cgcggcttgc tggctttcag
    31561 catccagcca cacatcattg gcgttaatgt cagagaaacc agcaacgata taccaatggc
    31621 gacagaaagc gtcacggcaa attcgcgtaa cagtcggccc ggcaatccgc ccatcaacag
    31681 cagcggcagg aacaccgcca ccagtgacag actcatcgac agcaccgtaa aaccgacttc
    31741 gcgagtacct tgcagtgcgg cttgcaacgg tttcattccc gcttccagat gacgggcaat
    31801 gttttccagc accacgatgg cgtcatccac cacgaaacca gtagcgatgg tgagcgccat
    31861 taacgaaagg ttattgagac tgaatccgca caggtacatc gccgcaaacg taccaatcag
    31921 cgaaaccggc accgaaacgg cgggaataat agtggcgcga cccgagcgca ggaataaaaa
    31981 taccaccaga atcaccagcg ccaccgagat aatcagcgtt tgctcgactt cttccagcga
    32041 ggagcgaatg gtgggggagc gatcctgggc aatttgcaga tcaatcgccg ccggaatggt
    32101 ttcctgcaac tccggtaatt ttgcccggat gctgtcaacc gtctggataa tattggcttc
    32161 cggcagcttg cggatcatca gcaaaatagc cggtttggca ttggtcatcc cggcgttacg
    32221 tacatcctgt acagagtcgg tcactgtcgc cacatcgccc agacgaaccg cgccgccgtt
    32281 gttgtaatga ataatcagcg gctgatattc gtcggcggtt tttagctcat cattggtctg
    32341 gatctgccag cggtgagtgc catcttccag cgccccctgc ggtttacgca cgttggcatt
    32401 gctgatggca gtgcgtacgt cgtccagcga gacgccctga ttaaacagcg cctgcggatt
    32461 cagcccgacg cgtacggcgg gcagtgagct gccgccgaca tcgacatcac caacaccgtc
    32521 gatttgcgaa atcgtcggag ccagctgcgt cgaggcaaaa tcgtacagtt caccctgcga
    32581 ataagtatcg gatgtcagcg tgaggatcat aattggcgca tccgacgggt tagctttgcg
    32641 ataggtcgga cggctgggca tcccgctggg cagcaaactt tgtgcagcgt tgatcgccgc
    32701 ctgcacatcg cgcgccgcgc cgttgatatc ccggtcaaaa tcaaactgca aaataatacg
    32761 cgtgctgccg agcgaactgc tggaggtcat ttcactgact ccggcaatgc gcccaagtga
    32821 gcgctccagc ggcgtggcaa cggaagacgc cattgtttct ggtgacgcac cgggcagcga
    32881 ggcgctgacc ataatcaccg gaaaatcgac ctgcggcagc ggggcgaccg gcagcatacg
    32941 gaagcccagt atgccgcaca gggtaatggc aaccgacagt aaaatcgtcg ccaccgggcg
    33001 gtaaatgaag agggcaaaaa acttcactta cgcctcctct tcatgacggg caaagcagct
    33061 tttggtccac aatgccaggc ggtcgaacag caaataaatc accggcgtgg taaacagcgt
    33121 cagcacctgg ctgacaatca gaccgccgac catgccgata cctaacggac gacgcagttc
    33181 cgcgccgacc ccggtactca acatcagcgg cagcgcgcca agcagagccg ccagagtggt
    33241 catcaggatc ggacgaaaac gcaacagaca agcctggtag attgcctcgc gcggcgacat
    33301 gccttgctcg cgctcggcag ccagcgcgaa gtcgatcatc atgatggcgt tcttcttcac
    33361 gataccgatc agcaaaataa tgccgataat cgcaatcaca tccagttcgc taccagcaat
    33421 cagcaacgcc agcagtgcgc caacccctgc ggtgggtagc gtcgagagaa tggtgatcgg
    33481 gtgaataaag ctctcgtaca gaatgccgag cacgatatac atcgccacca ccgccgcgac
    33541 aatcagccag acagtgctgc ccagcgccga ctggaaggcg agggtgctgc cctggaactg
    33601 cgtggtgata tccaccggca gattcagcgt cttttcggtg tccataatcg cctgcaccgc
    33661 atcgcccagc gaatagttat ccggcacgtt aaaggagatg gtcgttaccg ggaactgatc
    33721 cagatggttg atggaaagcg gcgcaaaacg ctgttcaact ttggcaattg agcttaacgg
    33781 caccacgccg ccgtcgctac tggtcaggcg aatggtatcc agcgccgcga ggcccggggt
    33841 aatttcggtg ttgtgctcca gcactacgcg atactggtta gcctgagtat aaatagtgga
    33901 aatcagtcgc tgaccaaacg cgttgtacag ggcgttatcg acatccgcca tgctgatccc
    33961 cagacggctg gcgctgtcgc gatcaacatt gacatacgcc accagccctt tgtcctgcca
    34021 gtcgctggag acatcagaaa gctgtggcag ttgctggagt ttttccatca actgtggcac
    34081 ccaggtactg agcgcatcca gtgaggtggc ctgcaaggta aactggtact gggtgcggct
    34141 gacctgagta tcaatagtca gatcctgcgt tggttgcagg aagagatcga cgcccggcac
    34201 tttatccacc gccgtttgca gacgggcaat gactttttgc actcggtcat cacgttcatc
    34261 cagcggtttg aggttgattt gtaaacgtgc actattcagc gacgggttag tgccatcaac
    34321 gccaacaaat gaggtcaggc tttgcactgc cggatcctgc aaaatcacgt ccgcgacctg
    34381 gcgttgtcgc tgggccatat tggcaaagga gctggattgc ggtgcctgca aagtgccctg
    34441 aataatgccg ttgtcctgta ccgggaagaa acctttcgga atgaacaccc ataagagaac
    34501 gctaagcagc agcgtgctga gcgccacgct taaggtcagc cacggatgat tcagcacctt
    34561 cgccagtcca cgaccatagg cggcgattat cctgtcgaac attttttccg aggcacggga
    34621 gaatcggttc tgtttacgca gcgactcctg gctgagcatc cgcgcgcaca tcatcggtgt
    34681 cagggtcagc gacaccaccg ctgagatcaa aatcgctacc gccagggtaa tagcaaattc
    34741 gcggaacagt cgcccgacga tatcgcccat aaacagcagt ggaatcaaca ccgcaatcag
    34801 cgagaaggtc agcgagataa tggtaaagcc gatttcaccc gcgcctttga gcgccgccgc
    34861 caacggtttt tcgccttttt cgatatagcg ggaaatgttt tcgatcacta cgatggcgtc
    34921 atcgaccacg aatccggtgg cgatagttaa cgccatcagt gtcaggttat tgattgaaaa
    34981 atcgagaaac accataaccg caaaagtgcc gattaacgac agcggtacag caacaccggg
    35041 aatgatggtc gccggaatat tgcgcaaaaa caggtagatg atcatgacta ccagcgcgat
    35101 agccatcatc aattcaaact gagtatcatc gacggatgcg cgaatattgg tggtgcgatc
    35161 ggaaagcact gtcaccttca ccgatttcgg cagactctcg gtgagctgtg gcagcatctg
    35221 ccggatgctg tcggcggtgg agataatgtt agcaccgggc tggcgctgaa cattcatcac
    35281 aatggcctgt tctttgttcg cccacgcgcc gagccagctg ttttctgctc cttgctctac
    35341 ggttgcgaca tcgcccagac gaatcggtgc gccgttctgg taggcgatga ttagctggcg
    35401 atactcttcg gcggattgca tctggtcgtt agcggaaagc gtgaccgcac gggaagggcc
    35461 gtcgaggcta ccttttgccg agttgacgtt agctccggta atggcggtgc gcacggtttc
    35521 gctggtcagg ccgagggcgg caatcgcctg ggcgttaagt ttgacgcgaa cagccggacg
    35581 ctgaccgccg gaaagcgtca ccagtccgac accggaaatc tgcgagattt tctgcgcgac
    35641 gcgggtttcc accatatctt ctacctgggt catcggcatg gcggttgagg tgacggcgag
    35701 cgtcatgatc ggcggatctg ccgggttcac tttgctgtaa accggcgggt taggcagatc
    35761 gctcggcaac aagttggtcg cagcgttaat cgcggcctgc acttcctgct cggcgacatc
    35821 gagcggtaat gttagctgga actgcaaagt gataactgac gcaccgccgg aactttgcga
    35881 cgacatctgt ttcaggccag acatctgccc gaactggcgt tcgagcggcg cggtaacggc
    35941 agaggtcatg acatccgggc tggcacctgg gtagagcgtg accacctgaa tggtcggata
    36001 gtccacttcc ggcagcgccg aaacgggcag ggcgcgataa ccgataatcc cggcgagtaa
    36061 gatcgccacc atcagcagcg tggtggccac aggacgcata ataaacaggc gcgacgggcc
    36121 gcctgtgctg ctcgggggta acacctgcat caggagcgtg ctcctttttt cgcgtattcg
    36181 cggctggtgg ctttctcttc cggagtagtg gcgctctggg cttccaccac ttccactttc
    36241 gccccttcgg tcaggcgatc aatgccgtct gtcaccacgc gatcgcccgc agaaatacct
    36301 gcacggatca ccactttctg actgtcctga atgcccggcg tcactagatg tttgctgacc
    36361 ttgttttcgc tactcagcac ccagacaaaa tggccttcat tgcccatttg cagggcggcc
    36421 gttgggatca ctacggcgtt ttgttcggtg tcgactaaca tgcgcgcgtt aacaaactga
    36481 ttgggaaaca gcgcatcatc ctgattatta aagcgtgctt tcactttaat cgtaccggtt
    36541 gtggcatcga tttggttatc gaggcttaac agcgtgcctt cacttaattt cttcgagttg
    36601 gtgcgatccc aggcttctac caccagcggt tttccggctt tctgcgcctg cacgacggta
    36661 gcgatatcgc tttccggcag ggtaaagagc aaatcgatag gatgcgtctg ggtgatcacc
    36721 acgatcccgg tggtatcacc actggagatt tggttaccaa catcaacctg cttgagacca
    36781 acgcgaccat cgactggtgc ggtgatgcgg ctccagtcga gttgcagctg cgcgctggcg
    36841 acgcttgctt catcagcctt aatggtgcct tcggtttcac tgaccagcgc ctgttgggca
    36901 tccagctcct gacgggagac gagattggtt tttgccagtt gctgataacg cgccagatca
    36961 cggcgggcgt tagcaagcgt ggctttatct tttgccagtt ggccctgggc ttgtgctaat
    37021 gcaactttga actggctggg gtcaatttct gccagtaaat cgcctgcttt gacctgctgg
    37081 ccttcctgga aatgtaacgc catcagttga ccgtccacgc ggctgcgcac cgtaacagta
    37141 ttagcggcgg taatggtgcc aagcccggtg aggtaacgcg gaactgcctg ttctacggcg
    37201 gtcgccgcct gaaccggggc taatgggccg gaacgcatac cacggcgacc acccgctggc
    37261 gattgctgcg cttgtttcgt cgcccctggg gctgcactct gggagtcatt gcggccttgc
    37321 cagaaccaga atgcggcgat ggcggcgata accaccacga ttacgattac ccaacgggat
    37381 ttataactgc ctttcatcgt taagagtttc tcttcctgaa acgtttcgcg gaatgatact
    37441 agtgtagcca gccaataagg gagaaaaatg gaggaattat gaaacactat cgggaatcgt
    37501 ctgaatggcg ggcacatttg cgagcacgca tccagtaata acacaggaaa ctattttatc
    37561 tacgcgttag cgatagactg catacagggc gaaaggaggt aagccgcaga tttcagccgg
    37621 atgctgaaac gggaaagccc ctcccgagga aggggcctta aataaggaaa gggtcatgat
    37681 gaagctactc atcatcgtgg tgctcttagt gattagctac ccagcatact aagactacca
    37741 gggcggggga aaccccgctc taccctcact cctgaaagta tgccttcacg ataagattgt
    37801 caatccgcag gctttgccgt ctgcgatcct gccagcaaaa attctttgcg agacgttacg
    37861 caataatcac actggaaact attttatctg caagtcagcg atagactaag tgcatggcga
    37921 aaggaggtaa gccgacgatt tcagcgggac gctgaaacgg gaaagcccct cccgaggaag
    37981 gggccttaaa taaggaaagg gtcatgatga agctactcat catcgtggtg ctcttagtca
    38041 taagcttccc cgcttactaa gactaccagg gcgggggaaa ccccgctcta ccctcactcc
    38101 tgaaagtatg ccttcacgat aagattgtca atccgcaggc tttgtagtct gcgatcctgc
    38161 cagcaaatat tctttgcgag tcgttacgca ataatcacag aggaaactat tttattcacg
    38221 cgttagcgat agactgcatt cagggcgaaa ggaggtaagc cgatgatttc agcgggacgc
    38281 tgaaacggga aagcctctcc cggagaagag ggcttttaat aaggaaaggg ttatgatgaa
    38341 gcacgtcatc atactggtga tactcttagt gattagcttc caggcttact aagaacacca
    38401 gggggagggg gaaacctctc cctaaccctc actcctgaaa ttatgtcact ccgcccttag
    38461 tgtcaatcga cggctctccg ttcttgcgag gcgaatagca aaattttctg cgccgccggg
    38521 cctaattctg aaagtttctt cgtttgctct tatttcatta ttgcagtcgg tatgataccg
    38581 gacctcgata attctctaag aaaggatttc ttatgagcga acaaatcacg tttgccacca
    38641 gcgattttgc cagtaacccg gaaccacgtt gcccctgcat tttgctgctg gatgtttctg
    38701 gctcgatgag cggcagacct attaatgaac ttaacgccgg attggtgacc tttcgtgatg
    38761 aactgcttgc cgatccgctg gctttaaaaa gagtggaact cggcattgtg acgttcggcc
    38821 cggtgcatgt ggaacaaccc tttaccagcg ccgctaattt ttttccgccc atcctgtttg
    38881 cccagggcga tacaccaatg ggtgcggcca ttaccaaagc cctggatatg gtagaggagc
    38941 ggaaacgtga gtatcgtgca aatggtattt cgtattatcg cccgtggatt ttcctgatta
    39001 ccgatggtgc accaaccgat gagtggcagg ctgcagccaa caaagtgttt cggggggaag
    39061 aagataaaag gtttgctttc ttttccatcg gtgttcaggg ggcggatatg aagactctgg
    39121 cacaaatcag cgttcgtcag cctttgcctc tgcaaggatt acaattccgt gaactgttta
    39181 gctggttatc cagttcgctg cgttcggttt cccgctccac gccgggaacg gaagttgtgc
    39241 tggaagcgcc aaaaggctgg acgtcagtgt gagctggcgt ctggtttatg catccgctgt
    39301 tggaacatcg cacatcagcg cggacttgcc ttgccaggat gcctgccaga tgcaggttgc
    39361 ctggctaaat gaccagcagc cattactggt gatgttcctt gctgatggcg caggtagcgt
    39421 ttcgcaggga ggagaaggcg cgacgctcgc cgtcaatgaa gcgatggctt atatgtcgca
    39481 aaaagtgcag ggtggggaat tggggcttaa tgatatcctc gccacggata ttgtgctgac
    39541 cgttcgtcag cgactttttg ccgaggcgga agccaaagaa ttagcagttc gcgattttgc
    39601 ctgcacgttt ctgggattga tttcatcggc taatggcacc ttgattatgc agattggcga
    39661 tggcggcgtg gtggtggatt ttggtcacgg tctgcaattg ccgcttacgc cgatggtggg
    39721 tgaatatgcc aatatgacgc acttcattac cgatgaagat gccgtttcca gactggaaac
    39781 tttcaccagc actgagcgtg tgcataaagt tgcagcattt acggatggta tccagcgact
    39841 ggcgttaaat atgctggata attctcctca tgtacctttc tttaccccgt ttttcaatgg
    39901 actggcgtca gcaacgcagg aacaactcga tttattacct gaattgttaa agcagttttt
    39961 gtccagcccg gcggtaaacg agcgtacgga tgatgataaa acgttggcac tggcgctgtg
    40021 gttaccatga aacccacttt atatactgct actggtgagt gcgttacgcc aggccgtgaa
    40081 ctgggcaaag gcggtgaagg cgcggtttat gatatcaatg agtttgtcga tagcgtcgcc
    40141 aagatttatc acacgccgcc acccgcctta aaacaggaca aacttgcctt tatggctgcg
    40201 acagctgacg cgcaattgtt gaattatgtc gcctggccgc aggcaacgct tcacggtgga
    40261 cgaggcggaa aagttatcgg ttttatgatg ccaaaagttt ctggtaaaga accgattcat
    40321 atgatctata gcccggcaca tcgtcgtcaa cgttaccctc attgtgcgtg ggattttcta
    40381 ctctatgttg cgcgcaatat tgcttcatct tttgctacgg ttcacgagca cgggcacgtc
    40441 gtgggtgacg taaaccagaa cagttttatg gtaggtcgcg acagcaaagt ggtactgatt
    40501 gatagcgact cctttcagat taacgccaat ggcacactgc atttatgcga agtcggcgtg
    40561 tcgcatttta cgccgccaga gctacaaacc ttgtcgtcat ttgtcggctt tgaacgcaca
    40621 gaaaatcacg ataattttgg ccttgcgttg ctgatttttc acgtcttgtt tggtggccgg
    40681 catccttatt ctggtgtgcc gcttatctct gatgcgggta atgcgctgga gacggatatt
    40741 acccatttcc gttatgccta cgcgtcagat aatcagcgac gtggtttaaa accgccgcca
    40801 cgatcgattc cgctatcgat gttaccgggc gatgttgaag ccatgtttca gcaggcattc
    40861 acggaaagtg gcgtggcaac cgggcgtccg acggctaaag cgtgggtagc ggcacttgat
    40921 tctctgcgcc aacagttaaa gaaatgtccc gtttcggcaa tgcatgttta tcccgctcat
    40981 ttgaccgact gcccgtggtg tgcgctggat aatcaaggcg ttatctattt tattgatctc
    41041 ggcgaagagg tcattaccac cggcggtgat tttgtgctgg cgaaagtctg ggcgatggtg
    41101 atggcgtcag tagcaccgcc agcattgcaa ttgccattac ccgatcattt ccaaccgact
    41161 ggcaggccgc ttcctttagg cctgttacgg cgcgaataca tcattctgat tgagatcgca
    41221 ctgtcagcgt tatcgctgtt gctttgcggc cttcaggcag aaccgcgtta tattattttg
    41281 gttcctgtgc tgtcggctat ctggattatt ggcagtctga caagcaaagc gtacaaagca
    41341 gaaatccagc aacgccgtga ggcatttaat cgcgcgaaaa tggactatga gcatttagtc
    41401 agccagatcc aacagttggg cgggctggaa ggttttatcg ccaaacgggc gatgctcgaa
    41461 aaaatgaagg acgaaattct cgggttaccg gaagaagaga aacgcgctct ggcagcactt
    41521 catgacactg caagggaacg gcagaagcag aagtttctgg agggattttt tattgatgtt
    41581 gcctctattc ccggcgttgg ccctgcgcgt aaagcggcgt tacggtcttt tggtattgaa
    41641 acagccgcag atgttacccg tcgtggcgtt aagcaagtga aagggtttgg cgaccatctg
    41701 acccaggcgg ttatcgactg gaaagcgagc tgtgaacgcc gttttgtgtt caggccgaat
    41761 gaagcgataa cgccagcaga cagacaagcg gtaatggcga aaatgaccgc caaacgacat
    41821 cggctggaat cgacgttgac tgtcggcgcg acagagttgc agcgattccg ccttcatgct
    41881 ccagcacgga ccatgccgtt gatggaacct ttacgtcagg cggcagaaaa actggctcag
    41941 gcgcaggcag atttaagccg ctgctgagcc attttctttt aacgaaacac cacttccgcc
    42001 cagcgtgcca gcccggcggt gacggagcca aagtcatcgc cgcctgcaat cggaattccc
    42061 ggcaactgtt ctgccagcgc ttttttaatc agcggcgaac gggcgctacc gccggtcagg
    42121 tagataacgt ccggtttttc ctgggcgtta tccagggcca gttgcacctg ttccagaatc
    42181 cgcgccagtg gctggctgag ggcgctttcc agcccttgct ggctaatcag cgtagccagt
    42241 tcatcgctga taaacggcag tgaggcgcgg gtttccgcta cgcttgaaag agcaattttg
    42301 cactcttctg cgctacgcac caggcgatag cttaaacgct gacgccagac tttctgtagc
    42361 agggccactt tttccggttc gcgggcatcg cgtaccagat cgttaagcag acgaccgttg
    42421 gcactactgt agaaatcact ctgcgcaggt acgtcgttga tggcaaccgc attccaccac
    42481 ggcagaatcg gcagggcgat gcctttttcg gtttcgccac ccatgcccag taacggcatc
    42541 aggtttttaa acgccagtgc gatgtccaga tcgttaccgc caatacggca accactgtga
    42601 cccagcaggc tggcttcacg atcgagacgc gaacgccact gcggccccat cagcagcaat
    42661 gaacagtcag tcgtaccacc gccgatatcc accaccagca cccgtttttc ttcctgcaag
    42721 gtggcttcgt aatccagccc agccgcgacc ggctcgtact ggaataccac gtccctgaat
    42781 ccggcacgct tcgccgcgcg ttccagaatc ccttgcgcct gggcgtttgc ttcatcgccg
    42841 cccagcccct ggaagttgat cgggcgacca atcaccgcct gagtaatcgc ttctggcagc
    42901 tgcgcctgcg cctgctggcg aatgtgcaac atcattgcgc agaccagatc ctcaaacagc
    42961 gctacctgct gcggttttaa gccgctggca ccgaggaacg attttggtga tttcacaaac
    43021 cacacttctt ctggatcatc aatgtactgt gccagtgagg aaagaccgaa ctgcacgctt
    43081 ttcgccgtaa catcgatatc ttcttcgcgg ttataacgaa tcgcccgacg taacagcgcc
    43141 tgcgtttcat cgtcgtctgc cggaacatca tgatggcggt acagccattc gcttaccgat
    43201 tcacgcgttg gcgcgcaaag cattgaaggc agcagcgtgc tgtcgttttc cattttcagt
    43261 aattgcggtt taccgtcacg catgaccgcc actgaacagt ttgctgtacc gtaatcaaaa
    43321 ccaataaaca cgaattaatc cccatgccgg tgaagaaggg gcgtgacttt agcgaaatgt
    43381 tgctgtcgcg acaaccggaa tatgaaagca aagcgtagcg tctgaataac gtttatgctg
    43441 aaagcggatg aataaggaga tgcgatgtat accctgaact ggcagccgcc gtatgactgg
    43501 tcgtggatgt tgggatttct cgccgcccgt gcagtgagtg gtgtggaaac ggtcgctgag
    43561 gattattatg cccgtagtct ggcggtgggc gaatatcgcg gcgtggtgac tgctattccg
    43621 gatatagccc gccatactct gcacataaat ttaagtgcag gtttagaacc cgttgccgct
    43681 gagtgtctgg cgaaaatgag ccgcctgttt gatctgcaat gtaacccgca gattgttaac
    43741 ggtgcgttgg gcaagttagg cgcggcgcgg cccggattgc gtttacccgg ctgtgttgat
    43801 gcttttgagc agggtgtgcg ggcgatttta ggccaactgg tgagcgtggc gatggcggca
    43861 aaattgactg ccaaagttgt acagctttat ggcgaacggc tggatgattt tccggagtat
    43921 atctgcttcc ccacgcctca gcggctggca gcagccgacc cgcaggcatt aaaagcgtta
    43981 ggcatgccgt tgaaacgggc agaggcactg attcatctgg caaatgcggc gctggagggc
    44041 agcttaccaa tgacaattcc gggcgatgtg gagcaggcga tgaaaacgct gcaaactttt
    44101 ccgggtatcg ggcgctggac ggcgaattat ttcgctttgc gtggctggca ggcgaaagat
    44161 gtttttctgc cggatgatta tctgattaaa cagcgatttc cggggatgac accggcacaa
    44221 atccgccgtt atgccgagcg ctggaagccc tggcgttctt atgcgctgtt gcatatctgg
    44281 tatacggaag gctggcaacc agacggaacg gacgaattgt aggcctgatg cgtcgcatca
    44341 ggcaatgggc aaacgctccc tcagttaatc gcgaaataac tgctattcac cagcaaatcc
    44401 agcggttggg catcggcaat cacatcacca taaatcagat cgacgccgat gccagaaagc
    44461 gtatccatca ctaagggtaa aacgactggc ccggcgatgg ttttcatccc gagtcgctga
    44521 gcgtgcccct gaataatcgt aatcagcatc tcatccatca aattaccctg cacgttggcg
    44581 cataactcac catcaagtag caggtaatct gccatattcg ctttcagcga gttgaagatt
    44641 tgcagatcgc ggcccacctg gctgagcact atccgacatc ccgccagccg cagtttttgc
    44701 acgctttctg cgtgatctaa aatcgcgtct gccggaataa tcagatgtaa taaccgtggt
    44761 ggtagagggc tattttccag ctgctcaagc agatcattca ccagcgtggc gctactcaaa
    44821 ccggcaacgg aaagggggag ggcgatgctt atgcctttac tggcaaccgc ttttgcggcc
    44881 agctggaaaa attcgtggaa tacccgtcgg tcaagagcat ggctaagtgc cggatcgctg
    44941 aagctacgac gaaatttttg ttcatcaata atctcgcctt cgcaactcca gagtttaagc
    45001 gaaatcagcc acaaattacg cgcttccggg atccgcggcg aagcgacacc gtgggccatc
    45061 atcatcaact gattctcttt aatcatccgc cactgttcat caagcgacat cgccgcccgt
    45121 tcgctatgtg cggcagcttg ctgtggttcg taaaccgtca cccggccccg tccaccattt
    45181 ttggaggcat aacaggcgat atcagcctgc gacatcactt ctgccgcctg atgattgttg
    45241 tcatcaatca aggtaatccc ggcactggca cctacccgat gcacacggcc ttcccatata
    45301 aagtgatagt cattcacggc actgataatg cgtgtagcga taaaacgcgc gctttcaaca
    45361 ttacagtctg gtagcagcag accaaattca tccccaccga gtcgcgccag cacgtcgctg
    45421 gaacgcagca tactcagcat caacgacgcc agttcgcgca gcaaagcgtc gcccgccgca
    45481 tgcccggcgc tgtcattcac cgctttaaag cgatcaagat cgataaacac cagggcatgt
    45541 cgctgatgtg tactgtttac cgtttgcagc agcatacgca gttgcttctc aaaactggcg
    45601 cgattggcga gatgcgtcag tgcatcatgg gaggcgctgt agctcagctg gcgcagcatt
    45661 ttgcgtgatt cggtaacgtc ctgaatcacc agaaccgaac caatattgct gccgtccaga
    45721 gtacttaacg gcgtaatact gtaatgcacg tcgtagctgc cgccgctccg gcagtgcaac
    45781 accacatctt gttcaatcgc ggaacgtgag gtgtcggcac tgtaaatgtt ctccatcagg
    45841 ggaccattgt cgccaaaggt aatatgcaac accgtcagga gcggaacacc taatgcttct
    45901 tcctgcgtcc agccgctcat cttctccgcc actggattca taaaggtaat tttcattgcc
    45961 atatcaatac agaccacggc ttcgccgatg gagtccagcg ttatgtgcag gcgctctttt
    46021 tcctgaaaca atgcctcgtt aagctgttta acctcagtca tatccatatt aatgccgagc
    46081 aggcgttcga cttcgccttc tttattcagt acccggttgg cgagggcgcg gatatggcga
    46141 ataccgtctt ttacggtaat gcgaaattcc agtttaaagg gcgagcgtga ttgcaacgaa
    46201 tcacgaatca ctttttcggc atgctggcga tcttccggca gcacgcactc gtaccacacc
    46261 tgccagttcg gtttgatatg tggaggaatt tcatacagct cgaacatccg cttatcccag
    46321 ctaaaaatat tcggcttcaa ctcccactcc cagatgccaa tcccgcccgc ttcgttagcc
    46381 agcgtgatgc gctccatcag ttgctgattc acctgttcgg tgcgttttag ctcgttaatg
    46441 tcttcaatct gagcgataaa atagagcggc gtgccatccg tgtggcgcac cagtgagacg
    46501 gcaagcaacg cccagacaac atcgccattg cggttgtagt agcgtttttc cattgaatag
    46561 gtgtttattt caccgcttat cagcttttca acctgttgga gatctttatt gagatcctcc
    46621 ggccaggtca gttgctgaaa ggtgagtccg cgcagctctt cctgactgta cccgagaaac
    46681 tggcagagcg ctttgttggt ttgcagccat tgtccctcgg tgcccactaa cgccataccg
    46741 atagcggaat attccatggc gttccgaaaa cgggtttcgc tttcggaaat gtgtttgcgt
    46801 tccgcacgaa aggcatacat caccatcgtc atgatgttgg cgggcagcag gatcagcaaa
    46861 aacggtagcc acggcatatg gctcatcagg tatgtacgcg gcgtagcaag cagggaggga
    46921 tccgcggcca tcatcagcga caccatcatc accgtggtaa ggaagatcaa aaaggcttcc
    46981 attcgtggca ggcgcacggc gctccacatc aacagcacaa taatgaaagt aaaaggccac
    47041 ggcagataca gcatcgaaag ccagcttaac gtcagtgtga tggctaacgt gagcagcgac
    47101 tcaaaaagca accgtgggtt gcgatggcgc agcagatagt gtggtttaaa taacaatccc
    47161 agcggcacca gtgccagagc gccgatggat tctgacagta cccatatcaa aaatgccctg
    47221 agaggatcgt ctccgggcgt cagcaggaca accagaacac cccctagcag aggcggaaca
    47281 atggcgctgc cgaatgccag acgcagccag tcagccagat tttgcaaggg gttataccac
    47341 ggcagcaatt tacgtagcag cactgccccg accacggctt caacaatatt gatggtcgtc
    47401 caggtcatgt tcagcgagct ggtggaaaaa agcaggatgg atgcggcgat atttcccagc
    47461 gagcagctca gcgcaattcc cggccacatg cgcccggcat ggcgataaaa cgccaccatc
    47521 atgatggacg tcgggaacca cagtggggcg agttgggtgc caaactgcga aagctcaagc
    47581 gagaaaaggg taaagataaa cgagactaaa cctaaactga ccaggtgaag cagcgggtgg
    47641 ggcagggcaa ttaatacatg ctgtgattgt ttgctcatta ccgctttatc cgcaagacca
    47701 ggtcgccagt attcgtttct gtgtttatgc tagtacaaaa gttttacatt ttatatgcga
    47761 attgctcata aagtgacgta aaggcggata atttgcgcaa ctgcgtataa cattttttac
    47821 cttgtataaa actgatcaac gtaatttgcc accgggaatt cttcgtcaac aattaactct
    47881 gagcgcgcgg cagcgctatt cgactggtat caggcggatg aaatccctat aattgccgcg
    47941 tttggcgctt cgtcgccccc ttcctaacat ccaggttaat caggtcgcta aatatatgac
    48001 tgatcagtct catcagtgcg tcattatcgg tatcgctggc gcatcggctt ccggcaagag
    48061 tcttattgcc agtacccttt atcgtgaatt acgtgagcaa gtcggtgatg aacacatcgg
    48121 cgtaattccc gaagactgct attacaaaga tcaaagccat ctgtcgatgg aagaacgcgt
    48181 taagaccaac tacgaccatc ccagcgcgat ggatcacagc ctgttgcttg agcatttaca
    48241 agcgttgaaa cgcggctcgg caattgacct gccggtttac agctatgttg aacatacgcg
    48301 tatgaaagaa acggtgacgg ttgagccgaa gaaggtcatc attctcgaag gcattttgtt
    48361 gctgacggat gcgcgtttgc gtgacgaact taacttctcc attttcgttg ataccccgct
    48421 ggatatctgc ctgatgcgcc gcatcaagcg tgacgttaac gagcgtgggc gttcaatgga
    48481 ttccgtgatg gcgcaatatc aaaaaaccgt gcgcccgatg ttcctgcaat tcattgagcc
    48541 ttctaaacaa tatgcggaca ttatcgtgcc gcgcggcggg aaaaaccgca tcgcgatcga
    48601 tatattgaaa gcgaaaataa gtcagttctt tgaataagct tgataaattg tgtaccgttc
    48661 agtgataacc tggtatgccc ttgacgtaat tggcgttaag ggagtgatgc gcgaaaggag
    48721 aaaatgccat gcgtctgtgt gaccgagata ttgaagcctg gcttgatgaa ggccgtttgt
    48781 cgatcaaccc acgtccgcca gtggagcgta ttaacggcgc gacggtggat gtacgcctgg
    48841 gcaataaatt tcgtaccttc cgtggtcaca cggcagcgtt tatcgatctg agcggtccca
    48901 aagatgaagt gagcgccgcg cttgaccgcg tgatgagcga tgagatcgtt ctcgacgagg
    48961 gcgaggcgtt ctatcttcac ccaggagagc tggcgctggc ggtgacgctg gagtcggtga
    49021 cgctgccagc cgatctggtg ggctggctgg acgggcgttc ctctttggcg cgtctggggc
    49081 tgatggtgca cgtcaccgcg caccgtatcg atccgggctg gtctggttgc attgtgctgg
    49141 agttctacaa ctccggtaag ctgccgctgg cgctgcgtcc gggcatgtta attggtgcgc
    49201 tgagctttga gccgctttcc ggcccggcgg cgcgacctta caaccgccgt gaagatgcga
    49261 aatatcgcaa ccagcagggc gcggtagcca gccgaatcga taaagactaa ttcaggccca
    49321 ttgaggatac catgagacga tttctgacga cgctgatgat actcctggtc gtgctggtgg
    49381 ccgggttatc tgcgttagtg ttgctggtga atccgaatga tttccgcgac tatatggtca
    49441 agcaagttgc tgcacgtagc ggttatcaat tgcagctcga cgggccactg cgttggcacg
    49501 tctggccgca gcttagtatc ctctccgggc gaatgtctct caccgcccag ggcgcaagcc
    49561 agccactggt tcgcgccgac aacatgcgtc tggacgtggc gcttttacca ctactgagtc
    49621 atcaactgag cgttaagcag gtgatgctaa aaggggcagt gatccaactg acgccgcaga
    49681 cggaagcggt gcgcagtgaa gacgctccgg ttgcaccgcg cgacaatacc ttgccggatc
    49741 tgtcagacga tcgcggatgg tcgtttgata tatccagtct taaggtggcg gacagcgtgc
    49801 tggtgttcca gcatgaagat gacgagcagg tgacaatccg caatatccgc ctgcaaatgg
    49861 aacaagatcc ccaacatcgt ggctcatttg agttctccgg gcgggttaat cgcgatcagc
    49921 gcgatctcac gatatccctt aacggtacgg tagatgcttc tgattatccg catgatttaa
    49981 cggcggctat tgaacaaatt aactggcagt tgcagggtgc agatttacca aaacaaggta
    50041 ttcaggggca ggggagtttc caggcccagt ggcaggagtc acataaacgc ctttcattta
    50101 accaaatcag cttgactgcc aatgacagca cgctgagcgg gcaagcacag gtcacgctga
    50161 cagagaaacc tgaatggcag ctgagactgc aattcccgca actgaatctt gacaacctca
    50221 tcccgcttaa tgaaaccgcg aatggtgaaa acggtgccgc gcagcagggg cagagccaat
    50281 caacgttgcc gcgcccggtt atttcttcgc gtattgatga accggcctat cagggactgc
    50341 aaggctttac ggctgatatt ttgttgcaag ccagtaacgt gcgctggcgc ggaatgaatt
    50401 ttacagatgt tgccacgcaa atgaccaaca agtcgggttt gctggaaatt actcaactgc
    50461 agggcaagct taacggtgga aaggtttcac tgccgggcac gctggacgcg acatcaataa
    50521 atccgcggat aaacttccag ccacggctgg aaaacgttga gattggtacc attctgaagg
    50581 cgtttaacta tccgatttcg ttgaccggaa agatgtcact ggctggtgat ttctccggtg
    50641 ctgacataga tgccgacgca ttccgccata actggcaagg acaggcacat gtcgaaatga
    50701 ccgacacgcg catggaaggg atgaacttcc agcagatgat tcagcaagcg gtagaacgta
    50761 atggtggtga tgtgaaggcc gctgaaaact tcgataacgt gacgcggctt gaccgcttta
    50821 ccaccgattt gacattgaag gatggcgtcg tgacgttaaa cgacatgcaa ggtcaatcgc
    50881 ctgtgctggc gctgacaggg gaaggtatgt tgaatctggc agatcaaacc tgcgacaccc
    50941 agtttgatat tcgggtcgtg ggtggctgga acggggaaag caaactgatt gatttcctca
    51001 aagaaacgcc agtaccgctg cgggtttatg gcaactggca gcaactcaat tacagcctgc
    51061 aagtggacca gctgctgcgc aaacatctac aggacgaagc gaaacgtcgc ctgaatgact
    51121 gggccgagcg gaataaagat tcccgcaatg gcaaagatgt gaagaagttg ctggagaaga
    51181 tgtagattac caggtgacct gtcctgtagg cctgataaga cgcgtaaagc gtcgcatcag
    51241 gcgttcgcgg cggcaccatt atattctgaa tatgtaagat tcaaggctgt tccgttcact
    51301 tgatgttcct cgctactatg gaacgctcaa gccggtgaac gtgccagggt ggctcaatcg
    51361 ccaccaccct ggcaacccgg gctcccggcg gtaaatcgcc gctggcgcgg ttccctcatc
    51421 ttattccttt cggctatcgg gtacgggcgc gaggtaacgt cctgtaagac gcgccctcag
    51481 cccacatcca tgtgggctgc cccggcctac aggaaacgat tcggcgattt acagccggac
    51541 ccacaccccc gctgtgatgt ccgtttacca cagacaacgc ttcattgctg aagttataag
    51601 gcgttacgca gcattgggta aaatggccga taccatcaca cctcgtactc catctcgcca
    51661 tccttacgta gcggtataat ttgcaccttc tgcacgcgat ggctttccac ctgcaacgtt
    51721 ttaagcaaat aatcccccac ctgaacttct tcgccaggtt ttggaatacg ctgtaaatat
    51781 tccatcaaca gcccggcaat ggtgtgatat tcacgttttt catccagcgg cagcggcaca
    51841 tattgcacca gatcttccag cggcatatga ccattcgccg tccaggaacc gtccgcattc
    51901 ttctgaatat catggcgggc gtcgatctct tccacttcgt tcggtaagtt accggcaatg
    51961 gtttcagtga cgtcacttaa tgtcacaatc ccttccaccg agccaaactc atccaccaca
    52021 aaagcaaagt gtgtgcgggc attacggaac tgctcgaggg caggtaacaa cggcaaggtt
    52081 tccgggaaca ccagtggctg gcgaatcaac acccgcaggt tgagcggttc gccgcgcaga
    52141 gactgttgta gcaggtcgat aacgtgaaca acaccgagca aatcttctgc gtcatcacca
    52201 tcagtaacca ccagccgcgt atgctgattt cgctccagca actggcggat ttcttcttcc
    52261 ggcgcgttga gatcgatatg ctcaatatcg tggcgcgacg tcataatgct gctgacagta
    52321 cgctggttaa gattaagtac ccgctcaatc atccgccgtt cctgcggatt aaagatctgc
    52381 tggttaccat gatccaccag catggacgcg gtttcggcgt ccagttccgc atcttctttt
    52441 tgcccgctaa gcaggcgcat taccgcttcg gtagtccgct ggcgtagcgt ctggttagcg
    52501 gaaagaaaac gtcgccggtt aaagatagcc aactgattga gcgcctcgat catcaccgag
    52561 aagccaatgg cggcgtacag gtagcctttc ggaatgacga agccgaaacc ttctgccacc
    52621 aggctaaagc caatcatcaa caggaagctt aagcagagaa taacgatggt cgggtgactg
    52681 ttaacaaatt gcgttaacgg cttgctggcc atcaacatca ggctgatagc gataacaacg
    52741 gcggccatca tgaccagtaa atggtcgacc atcccgacgg cggtaatcac cgagtcgagt
    52801 gagaagatgg cgtccagtac cacaatttgt gtcaccaccc cccagaactt cgcacctttg
    52861 cgttgtgtgg ggttattgct gtcttttcct tccagccgtt cgttcagctc catcgtggct
    52921 ttgaacaaca ggaagaaacc accaaacagc atgattaagt cgcgggcgct aaaggtaaac
    52981 gagcggaagc tgaacagcgg ttgcgtcagg gtgaccagcc aggagattga cgccagcagt
    53041 aacaggcgca ttaacatcgc cagcagcagc ccggtaaccc gtgcgcggtc gcgctgcttc
    53101 ggcggtagtt tttcggcgag gatggcaata aagaccaggt tatcaatgcc gaggaccagt
    53161 tcgatcacaa tcagcgtgat taacccggcc cagatagacg gatcggcaat ccattccata
    53221 gtaagtacaa aacctattcg ttgtatgaca aatgtcacaa ttcgatcatg gataaatcag
    53281 ggcaaaaatg caatgttgcg gcactattta tctcacatta tttgaggatt ataacatcgc
    53341 attatccctg aattaaaagt ggtaataata aaacattatt taagaaatat cgcatgtgga
    53401 gacgcaatat taaatattgt caacctaaag aaactcctaa aaaccatatt gaatgacact
    53461 taatataatt cttaaaaata gccaattgcc gaattgttac cttgcctgct attccgttag
    53521 ctgtaacact tcctcctgca ttattggaga gccaatattc aattaccata atgtcacctt
    53581 atattcggaa gttaatttcc gcaataaccc tttctcatca acgattgtat gcagagaggg
    53641 tttgaaaaat taagctaaat cagtgtattg gtagctaaaa agccaggggc ggtagcgtgt
    53701 ctggatgcct gaaagaccag tctgaattat tctgtcaata gtctgcggat gaaatcaatt
    53761 tttttaggac tgatgccagt taaattttta ttcaattaac tgcaaggtaa atgtgcatgg
    53821 cgacattgct attaatagtg cacaggataa ttactctgcc aaagtgataa ataaacaatg
    53881 atgaaatcca aaatgaaatt gatgccatta ttggtgtcag taaccttgat aagcggttgc
    53941 acagtacttc cgggcagcaa tatgtcgacg atgggcaaag acgtcatcaa acagcaggac
    54001 gctgatttcg atctcgacaa aatggtgaat gtttatccgc tgaccccgcg cctgattgac
    54061 caattacgcc cacgcccgaa tgtagcgcgc cccaatatga cgctggaaag tgagatcgcg
    54121 aattaccagt atcgcgtcgg gccgggagac gttcttaatg tcaccgtctg ggatcacccg
    54181 gaactcacca cgccagctgg tcagtaccgc agctccagcg acaccggcaa ctgggtacag
    54241 cctgacggca ctatgttcta cccgtatatc ggcaagattc acgtcgtggg gaaaacgctc
    54301 gctgaaatcc gcagtgatat taccgggcgc ttagcgacgt acatcgctga cccgcaggtg
    54361 gacgttaata tcgccgcctt ccgctcacaa aaggcctata tctccggtca ggtgaataaa
    54421 tccggtcaac aggcgatcac caacgtacca ctgaccattc tcgatgccat caacgccgca
    54481 ggtggcctga ccgacaccgc tgactggcgc aacgtggtgc taacacacaa tggtcgtgaa
    54541 gaacgcattt ctttgcaggc gctgatgcaa aacggcgacc tcaatcagaa ccgactgctt
    54601 taccccggcg atattctcta cgtgccgcgt aatgatgatc tgaaagtatt tgtgatgggt
    54661 gaagtgaaga aacagagcac cctgaaaatg gactttagcg gcatgaccct gacggaagcc
    54721 ttgggtaatg ctgaaggcat cgacatgacc acctccaacg ccagcggcat ctttgtcatt
    54781 cgtccgctga aaggcgaggg cgggcgtaac ggcaagattg ccaatatcta ccagctggat
    54841 atgtccgatg cgacgtcgct ggtgatggcg acagaattcc gcctgcaacc ttatgacgtg
    54901 gtgtatgtca ccaccgcccc ggtttcccgc tggaaccgtc tgatcaatca gttgctgcca
    54961 actattagcg gtgtccgtta catgacggat acagccagcg acattcataa ctggtaatcg
    55021 tcatgtttaa caacatttta gttgtctgtg tcggcaatat ttgccgttcc ccgacggcgg
    55081 aacgcttact gcaacgttat cacccggaac tgaaagtgga gtccgctgga ctcggcgcgc
    55141 tggtcggtaa gggcgctgac cctactgcta tcagcgtcgc cgcagaacat caactgtctc
    55201 tggaaggtca ctgtgcccgt caaatcagcc gccgcctgtg tcgcaactac gacctgattt
    55261 tgaccatgga aaagcgccat atcgaacgct tatgcgagat ggcacccgag atgcgcggca
    55321 aagtgatgct gtttggtcac tgggataacg aatgtgaaat ccccgatccg tatcgcaaaa
    55381 gccgggaaac gtttgcagcg gtgtacacat tacttgaacg gtctgcccgc cagtgggcgc
    55441 aggcattgaa cgcagagcag gtataagaat gacagaaaaa gtaaaacaac atgccgctcc
    55501 ggtaacgggc agtgatgaaa tcgatattgg tcgcctggtc ggcaccgtca ttgaagcgcg
    55561 ctggtgggtg attggcatca ccgccgtatt tgccctctgt gccgtggttt acactttctt
    55621 cgccacgccg atttatagtg ccgacgcact ggtacaaatc gagcaaagca gcggcaattc
    55681 gttagtgcag gacattggtt cggcattagc caacaaaccg cctgcatcgg acgccgagat
    55741 ccagttgatt cgttcgcgtc tggtgcttgg taaaacggtg gacgatctcg acctcgatat
    55801 tgcagtgagc aaaaacacgt tcccgatttt cggggcgggc tgggatcgcc tgatgggacg
    55861 ccagaacgag acggtgaaag tgactacctt taaccgcccg aaagagatgg cggatcaggt
    55921 gtttacgctt aatgtgctgg atgacaaaaa ctacaccctg agcagtgatg gcggctttag
    55981 cgcccgtgga caagcgggcc agatgctgaa aaaagaaggc gtcacgctga tggttgaagc
    56041 cattcacgcc cgcccgggca gtgagtttac cgtcaccaaa tactccacgc tggggatgat
    56101 caatcaactg caaaacagcc tgacggtaac ggagaacggc aaagacgcag gcgtactgag
    56161 cctgacttat accggtgaag atcgcgaaca gatccgcgac attcttaata gcatcgcccg
    56221 taactatcag gaacaaaata ttgagcgcaa atcggcggaa gcgtcgaaaa gcctcgcttt
    56281 cctcgcgcaa cagttaccgg aagtacgtag ccgccttgat gttgccgaaa acaaactgaa
    56341 tgccttccgt caggataaag attctgttga tctgccgctg gaagcgaaag cggtgctcga
    56401 ttcgatggtg aacatcgacg cccagttgaa cgaactgacc tttaaagagg cggaaatctc
    56461 caagctgtac accaaagttc acccggcgta tcgcacgctg ctggagaaac ggcaggcgct
    56521 ggaagacgaa aaagccaaac ttaacggtcg cgtaacggcg atgccgaaaa cccagcagga
    56581 aattgtccgt ctgacccgcg atgtcgagtc tgggcagcag gtctatatgc aactgctgaa
    56641 taaagagcag gagctgaaaa tcaccgaagc cagcaccgtc ggcgatgtgc gcattgttga
    56701 cccggcaatc acccagcctg gcgtgctgaa accgaagaaa ggactgatta tcctcggcgc
    56761 aattatcctc ggcctgatgc tctctatcgt gggtgtgctg ctgcgctcgt tgtttaatcg
    56821 cggcatcgaa agcccgcagg tgctggaaga acatggtatc agcgtctatg ccagcatccc
    56881 gttgtcggaa tggcagaaag cgcgcgatag cgtcaaaacc atcaaaggga ttaaacgcta
    56941 taaacagagc cagctactgg cggtggggaa tccaaccgat ctggcgattg aagccatccg
    57001 cagtctgcgt accagtctgc acttcgcgat gatgcaggcg cagaacaatg tgttgatgat
    57061 gacaggggtg agcccgtcaa tcggtaaaac ctttgtctgc gccaacctgg cggcggtgat
    57121 cagtcagacc aataaacggg tgttgttgat cgactgcgat atgcgcaaag gctacaccca
    57181 cgagctgttg ggtaccaata acgtcaatgg cctgtcggaa attctgattg gccagggcga
    57241 tattactacc gcagctaaac cgacctctat tgccaaattt gacctgatcc cgcgcggtca
    57301 ggtaccgcca aatccttctg aactgttgat gagcgaacgc tttgccgaac tggtgaactg
    57361 ggcgagtaaa aactatgacc tggtgttgat tgatacgccg ccgattctgg cagtgaccga
    57421 tgcggcaatt gttggtcgtc atgttggaac cacgttaatg gtggcgcgtt atgcggtcaa
    57481 cacattgaaa gaagtggaaa ccagtctgag ccgctttgag caaaatggta ttccggtgaa
    57541 aggggtgatt ctgaactcca tcttccgccg cgccagcgcg tatcaggatt atggctatta
    57601 cgaatacgaa tataagtcgg atgcgaaata acgacatccg ctgtcggatg cgatgctgac
    57661 gcatcttatc cgacctacct tcacgccgca tccggcaagc aaaccagctc cgtaggccgg
    57721 ataaggcgct cacgccgcat ccggcaacag aacccgtaaa caagcttata aaccggcaga
    57781 acatctcgac actccgggag aacaacctat gaaagacaat ccgctgattt caatctatat
    57841 gccgacctgg aaccgccaac aactggcgat tcgggcgata aaatcggtcc tgcgccagga
    57901 ctacagcaac tgggagatga tcatcgtgga tgattgctcc acctcctggg aacaactgca
    57961 acagtacgtc actgccctca acgatccgcg tattacctac attcacaacg acattaacag
    58021 cggggcgtgc gcggtacgta accaggcgat tatgctggcg caaggggaat acattaccgg
    58081 gatcgatgac gatgatgaat ggacgcccaa ccgcctgagc gtcttcctcg cccataaaca
    58141 gcaactggtc actcacgcct ttttgtacgc taacgactac gtttgccagg gcgaagtcta
    58201 ttcccaacca gcaagcttac cactgtatcc caaatcgccg tactcacgcc gcctgttcta
    58261 taaacgcaat atcattggca atcaggtttt tacctgggcg tggcgtttca aagagtgctt
    58321 gttcgatacc gaactgaaag cagcacagga ttacgacatc ttcctgcgga tggtggtgga
    58381 gtatggcgaa ccgtggaaag tggaagaggc gacgcagatc ctgcatatca atcacggtga
    58441 aatgcagatc acctcgtcac cgaaaaaatt ctccgggtac ttccactttt accgcaagca
    58501 caaagacaaa ttcgaccgtg ccagtaaaaa atatcagctg tttaccctct accagatccg
    58561 caataaacgc atgacctggc gcactttgct gacgctgctg tcggtgcgta acggcaaacg
    58621 tctggctgat ggtattcggg ggcgctaaag atgctggaag atctgcgcgc caacagctgg
    58681 agtttacgcc cgtgctgcat ggttcttgcc tatcgcgttg ctcatttttg ttcggtgtgg
    58741 cgcaaaaaga acgtcctcaa caatctgtgg gcggccccgc tgctggtgct gtatcgcatt
    58801 atcaccgaat gctttttcgg ttatgaaatc caggcagccg caaccattgg ccgccgcttt
    58861 actatccatc acggttacgc cgtagtgatc aataaaaacg tggttgcggg ggatgatttc
    58921 accattcgcc acggcgtcac tatcggcaat cggggtgccg ataacatggc atgtccacac
    58981 attggcaacg gcgtcgaact cggtgccaac gtcattattc ttggtgatat cacgcttggt
    59041 gacaacgtca ccgtgggcgc gggcagcgtg gtgctcgact ctgtcccgga caacgcgctg
    59101 gtggtgggag aaaaagcgcg agtgaaggta attaaatgaa tattttgcaa tttaatgtgc
    59161 gactggcgga aggcggggca gcaggtgtgg cgttagatct ccaccagcgt gcgctgcaac
    59221 aggggctggc gtcacatttt gtctacggtt acggcaaagg cggcaaagag agcgtcagcc
    59281 atcagaacta tccgcaggtc atcaaacata cgccgcggat gaccgcgatg gcgaatattg
    59341 ccctgtttcg tctgtttaat cgcgatctgt ttggcaattt caatgagtta tatcgcacca
    59401 ttactcgcac accgggtccg gtggtcctgc attttcatgt gctgcacagc tactggctaa
    59461 atcttaagag cgtggtgcgc ttttgcgaaa aagtgaaaaa ccacaaaccg gatatcactc
    59521 tggtctggac gctgcacgat cactggagcg ttaccggacg ctgcgccttt accgacggtt
    59581 gcgaaggctg gaaaacgggc tgccagaaat gcccgacctt aaataactat ccgccggtga
    59641 agattgatcg cgcgcatcag ctggtggcgg gcaaacgcca gttattccgc gagatgctgg
    59701 cgctgggctg tcagtttatt tcccccagcc agcatgtggc tgacgctttc aatagtctgt
    59761 acgggccagg gcgttgccgg attatcaata atggcattga tatggcaacc gaagcgattc
    59821 tggcagatct gcctccggtg cgtgaaaccc agggcaagcc gaaaatcgcg gtggtggcgc
    59881 atgacttgcg ttacgacggc aagactaacc agcaactggt gcgtgagatg atggcgctgg
    59941 gcgacaaaat cgaactgcat acctttggta agttctcgcc gttcaccgct ggcaacgtgg
    60001 ttaatcacgg ctttgaaact gacaagcgca agttgatgag cgcgctcaat cagatggatg
    60061 cgctggtatt cagttctcgc gtcgataact acccgctgat tttgtgtgag gcgttatcaa
    60121 ttggcgtgcc ggtgattgcc acccatagcg acgcggcacg ggaagtgttg caaaaatccg
    60181 gcggtaaaac cgtcgacgaa gaagaggtgc tgcaactggt ccagttaagc aaaccggaaa
    60241 tcgcgcaggc gatatttggt accacgctgg ctgagttcag ccaacgcagc cgcgccacct
    60301 acagtggaca acagatgctg gaggagtatg tcaacttcta tcagaatctg tagctacctg
    60361 ctgctgccgc tgatctacct gctggttaac gtcaaaatcg cccagcttgg cgaaagtttc
    60421 cccatcacta tcgtcacttt tttacctgtc ttgttactgc tgtttttaga acgcatcagc
    60481 gttaaaaaat tgatgattgc cttagggatt ggtgcgggac tcacggcgtt caactatctg
    60541 tttggtcagt cgttggatgc cagtaaatac gtcacatcaa ccatgctgtt tgtctatatt
    60601 gtgatcatta ttggcatggt gtggagtatt cgctttaaaa cgatttcgcc acacaaccat
    60661 cgcaagatat tacgtttctt ttatctggtg gtcgggctgg tggtggcgct ggcggcggtg
    60721 gagatggcgc aaattatcct caccggtggc agcagtatta tggagtcgat ttcgaaatat
    60781 ctgatttaca gcaacagcta tgtactgaat ttcattaaat tcggcggcaa gcgcacgaca
    60841 gcactttatt tcgaaccggc atttttcgct ctggcattaa tctcaatttg gctcagcatc
    60901 aaacagtttg gtatcaaaac gcctaaaacc gatgctatga ttctcgcagg gataatatta
    60961 tccggatcgt tttcaggggt tatgaccttt atcctgtttt atttgctgga gtgggcattt
    61021 caatatctga ataaagaggc gattaagaaa aagttaccgt tggcattgat ttctctggct
    61081 gtattcctgg ttggtgtggt aatcgcgttt ccttatattt ccacccgtct gggcgattta
    61141 ggtacggaag gatcgtcatc gtattatcgt attgtcggtc cgctggtgat ggtcggttat
    61201 tctttgaccc atattgacgg tgtagtcaga tttggctcac tttatgaata cgtcgcatca
    61261 ttcggaatat ttaacggtgc ggatgtcgga aaaaccatag acaatggttt gtatctgctg
    61321 attatttatt tttcctggtc cgcagtgttt ttatcgctgt ggtacatggg gaaagtgata
    61381 aaaatgatga tcaacgcttt tggtgataac cgcaattttc gcgtgcaatt atatcttttt
    61441 actccggtat cgctgttttt taccggttcg atatttagcc cggaatatgc atttttaatc
    61501 gtctgtccgt ttattttgcg aaaagcgtta aatattacga ggtaagaata agaacatgtt
    61561 gcttagcata atcactgtcg cgtttcgtaa cctcgaaggg atagtcaaaa cacatgcctc
    61621 gctggcgcat ctggcgcagg cggaagatat cagcttcgaa tggattgttg tcgatggcgg
    61681 ttccaatgac ggcacccgtg agtatctgga aaatctcaat ggtatctata acctacgctt
    61741 tgtcagcgag ccagataacg gtatctacga cgccatgaac aaaggcatta cgatggcaca
    61801 aggcaagttc gcgttgtttc tcaattcggg cgatattttt catcaggatg ccgcaaattt
    61861 tgtccgtaag ttaaaaatgc aaaaagataa catgatgatc accggcgatg cgctgctgga
    61921 ttttggcgac gggcataaaa ttaaacgtag cgccaaaccg ggctggtata tttatcacag
    61981 cctgcccgcc agtcatcagg cgatattttt ccctgtatcc ggcttgaaaa aatggcgtta
    62041 tgacctggaa tataaagttt cttccgacta cgcgctggca gccaaaatgt ataaagccgg
    62101 ttatgcattt aaaaaactca atggcctggt gtctgaattt tccatgggtg gggtatctac
    62161 caccaataat atggaattgt gtgctgacgc gaaaaaagtc caacgacaaa tattacatgt
    62221 acctggcttt tgggctgaat tatcctggca tttacgccaa cgtactacct caaagacgaa
    62281 agccttatat aacaaagtct gaatataagg agaaccaatg caagatttaa gcggtttctc
    62341 ggtgccgaaa gggttccggg gcggcaacgc tattaaagtg caattatggt gggcagtaca
    62401 ggcaacaata tttgcctggt cgccacaagt attgtatcgc tggcgggcat ttttattacg
    62461 tttattcggc gcaaaaatag gaaaaaacgt agttattcgt ccgtcagtaa aaattaccta
    62521 tccgtggaaa ttaaccttag gtgattacgc gtgggtcggc gatgacgtca atttatatac
    62581 cctcggtgaa ataaccattg gcgcacattc ggtgatatcg caaaaaagtt atttatgcac
    62641 cggtagccac gaccatgcaa gtcaacattt caccattaat gctacgccta ttgtgattgg
    62701 cgagaaatgc tggctggcaa ccgatgtttt tgttgcccct ggcgtcacga ttggcgacgg
    62761 caccgtcgtg ggtgcacgaa gcagtgtttt taaaacgctt ccggcaaatg tggtttgccg
    62821 ggggaatccc gcagtggtga tacgcgaacg cgttgaaact gaataaattc aaaaaataca
    62881 gaggaataag acatgtcaaa agtcgctctc atcaccggtg taaccggaca agacggttct
    62941 tacctggcag agtttctgct ggaaaaaggt tacgaggtgc atggtattaa gcgtcgtgca
    63001 tcgtcattca acaccgagcg cgtggatcac atttatcagg atccgcacac ctgcaacccg
    63061 aaattccatc tgcattatgg cgacctgagt gatacctcca acctgacacg cattttgcgt
    63121 gaagtgcagc cggatgaagt ttacaacctg ggcgcaatga gccacgttgc ggtttctttt
    63181 gagtcaccgg aatataccgc agacgtcgat gcgatgggta cgctgcgcct gctcgaggcg
    63241 atccgcttcc tcggtctgga aaagaaaacc cgtttctatc aggcttccac ctctgaactg
    63301 tatggtctgg tgcaggaaat tccgcagaaa gaaaccacgc cgttctaccc acgctctccg
    63361 tatgctgtcg ccaaactgta cgcctactgg atcaccgtta actaccgcga atcctacggc
    63421 atgtacgcct gtaacggtat tctcttcaac catgaatccc cgcgccgcgg cgaaaccttc
    63481 gttacccgca aaatcacccg cgcaatcgcc aatatcgccc aggggctgga gtcgtgcctg
    63541 tacctcggca atatggattc cctgcgtgac tggggccatg ccaaagacta cgtaaaaatg
    63601 cagtggatga tgctgcaaca ggaacagccg gaagatttcg ttatcgcgac cggcgttcag
    63661 tactccgtgc gtcagttcgt ggaaatggcg gcagcacagc tgggcatcaa actgcgcttt
    63721 gaaggcacgg gcgttgaaga gaagggcatt gtggtttccg tcaccgggca tgacgcgccg
    63781 ggcgttaaac cgggcgatgt gattatcgcc gttgacccgc gttacttccg tccggcagaa
    63841 gttgaaacgc tgctcggcga cccgaccaaa gcgcacgaaa aactgggctg gaaaccggaa
    63901 atcaccctca gagagatggt gtctgaaatg gtggctaatg acctcgaagc ggcgaaaaaa
    63961 cactctctgc tgaaatctca cggctacgac gtggcgatcg cgctggagtc ataagcatga
    64021 gtaaacaacg catttttatc gctggccatc gtgggatggt cggttctgcc atcaggcggc
    64081 agctcgaaca gcgcggtgat gtggaactgg tattacgcac ccgcgacgag ctgaacctgc
    64141 tggacagccg cgcggtgcat gatttctttg ccagcgaacg cattgaccag gtctatctgg
    64201 cggcggcgaa agtgggcggc attgttgcca acaacaccta tccggcggat ttcatctacc
    64261 agaacatgat gattgagagc aacatcattc acgccgcgca tcagaacgac gtgaacaaac
    64321 tgctgtttct tggatcgtcc tgtatctacc cgaaactggc aaaacagccg atggcagaaa
    64381 gcgagttatt gcagggcacg ctggagccga ccaacgagcc ttacgccatt gccaaaatcg
    64441 ccgggatcaa actgtgcgaa tcatacaacc gccagtacgg acgcgattac cgctcagtca
    64501 tgccgaccaa cctgtatggc ccgcatgaca acttccaccc gagtaattcg catgtgatcc
    64561 ctgcattgct gcgtcgcttc cacgaggcga cggcacagaa tgcaccggac gtggtggtat
    64621 ggggcagcgg tacaccgatg cgtgaattcc tgcacgtcga tgatatggcg gcggcgagca
    64681 ttcatgtcat ggagctggcg cacgaagtct ggctggagaa cacccagccg atgctgtcgc
    64741 acattaacgt cggcacgggc gttgactgca ctatccgcga gctggcgcaa accatcgcca
    64801 aagtggtggg ttacaaaggt cgggtggttt ttgatgccag caaaccggat ggtacgccgc
    64861 gcaaactgct ggatgtgacg cgcctgcatc agcttggctg gtatcacgaa atctcactgg
    64921 aagcggggct tgccagcact taccagtggt tccttgagaa tcaagaccgc tttcgggggt
    64981 aatgatgttt ttacgtcagg aagactttgc cacggtagtg cgctccaccc cgcttgtctc
    65041 tctcgacttt attgtcgaga acagtcgcgg cgagtttctg cttggcaaaa gaaccaaccg
    65101 cccggcgcag ggttactggt ttgtgccggg agggcgcgtg cagaaagacg aaacgctgga
    65161 agccgcattc gagcggctga cgatggcgga actggggctg cgtctgccga taacagcagg
    65221 ccagttttac ggtgtctggc agcactttta tgacgataac ttctccggca cggatttcac
    65281 cactcactat gtggtgctcg gttttcgctt cagagtcgct gaagaagatc tgatactgcc
    65341 ggatgagcag catgacgatt accgctggct gacgccggac gcgctgctcg ccagtaacga
    65401 tgttcacgct aacagccgcg cctattttct cgctgagaag cgtgccggag tacccggatt
    65461 atgaaaatac tggtctacgg cattaactac tcgccggagt taaccggtat cggcaaatac
    65521 accggcgaga tggtggaatg gctggcggca caaggtcatg aggtgcgggt tattaccgca
    65581 ccgccttact acccgcagtg gcaggtgggc gagaactatt ccgcctggcg gtacaaacga
    65641 gaagaggggg ccgccacggt gtggcgctgc ccgctgtacg tgccaaaaca gccgagcacc
    65701 ctgaaacgcc tgttacatct cggcagtttt gccgtcagca gtttctttcc tctgatggcg
    65761 caacgtcgct ggaagccgga tcgcattatc ggcgtggtgc caacgctgtt ttgcacgccg
    65821 ggaatgcgcc tgctggcgaa actttctggt gcgcgtaccg tgctgcatat tcaggattac
    65881 gaagtggacg ccatgctggg gctgggcctt gccggaaaag gcaaaggcag caaagtggca
    65941 cagctggcaa cggcgttcga acgtagcgga ctgcataacg tcgataacgt ctccacgatt
    66001 tcgcgttcga tgatgaataa agccatcgaa aaaggcgtgg cggcggaaaa cgtcatcttc
    66061 ttccccaact ggtcggaaat tgcccgtttt cagcatgttg cagatgccga tgttgatgcc
    66121 cttcgtaacc agcttgacct gccggataac aaaaaaatca ttctttactc cggcaatatt
    66181 ggtgaaaagc aggggctgga aaacgttatt gaagctgccg atcgtctgcg cgatgaaccg
    66241 ctgatttttg ccattgtcgg gcagggcggc ggcaaagcgc ggctggaaaa aatggcgcag
    66301 cagcgtggac tgcgcaacat gcaatttttc ccgctgcaat cgtatgacgc tttacccgca
    66361 ctgctgaaga tgggcgattg ccatctggtg gtgcaaaaac gcggcgcggc agatgccgta
    66421 ttgccgtcga aactgaccaa tattctggcg gtaggcggta acgcggtgat taccgcggag
    66481 gcccacacag aactggggca gctttgcgaa acctttccgg gcattgcggt ttgcgtagaa
    66541 ccggaatcgg tcgaggcgct ggtggcgggg atccgtcagg cgctcctgct gcccaaacac
    66601 aacacggtgg cacgtgaata tgccgaacgc acactcgata aagagaacgt gttacgtcaa
    66661 tttataaatg atattcgggg ataattatgg cgcagtcgaa actctatcca gttgtgatgg
    66721 caggtggctc tggtagccgc ttatggccgc tttcccgcgt actttacccc aagcagtttt
    66781 tatgcctgaa aggcgatctc accatgctgc aaaccaccat ctgccgcctg aacggcgtgg
    66841 agtgcgaaag cccggtggtg atttgcaatg agcagcaccg ctttattgtc gcggaacagc
    66901 tgcgtcaact gaacaaactt accgagaaca ttattctcga accggcaggg cgaaacacgg
    66961 cacctgccat tgcgctggcg gcgctggcgg caacacgtca tagcccggag agcgacccgt
    67021 taatgctggt attggcggcg gatcatgtga ttgccgatga agacgcgttc cgtgccgccg
    67081 tacgtaatgc catgccgtat gccgaagcgg gcaagctggt gaccttcggc attgtgccgg
    67141 atctaccaga aaccggttat ggctatattc gtcgcggtga agtgtctgcg ggtgagcagg
    67201 atacggtggc ctttgaagtg gcgcagtttg tcgaaaaacc gaatctggaa accgcccagg
    67261 cctatgtggc aagcggcgaa tattactgga acagcggcat gttcctgttc cgcgccggac
    67321 gctatctcga agaactgaaa aaatatcgtc cggatattct cgatgcctgt gaaaaagcga
    67381 tgagcgccgt cgatccggat ctcgatttta ttcgtgtgga tgaagaagcg tttctcgcct
    67441 gcccggaaga gtcggtggat tacgcggtca tggaacgtac ggcagatgcc gttgtggtgc
    67501 cgatggatgc gggctggagc gatgtcggct cctggtcctc attatgggaa attagcgccc
    67561 acaccgccga gggcaacgtt tgccacggcg atgtgattaa tcacaaaact gaaaacagct
    67621 atgtgtacgc cgaatctggc ctcgtaacca ccgtcggggt gaaagatctg gtagtggtgc
    67681 agaccaaaga tgcggtgctg attgccgacc gtaacgcggt gcaggatgtg aaaaaagtgg
    67741 tcgagcagat caaagccgat ggtcgccatg agcatcgggt gcatcgcgag gtctatcgcc
    67801 cgtggggcaa atatgactct atcgacgcgg gcgaccgcta ccaggtgaaa cgcatcaccg
    67861 tgaaaccggg cgagggcttg tcggtacaga tgcaccatca ccgcgcggaa cactgggtag
    67921 tggtcgcggg aacggcaaaa gtcactattg acggtgatat caaactgctt ggtgaaaacg
    67981 agtccattta tattccgctg ggggcgacgc actgcctgga aaacccgggg aaaattccgc
    68041 tcgatttaat tgaagtgcgc tccggctctt atctcgaaga ggatgatgtg gtgcgcttcg
    68101 cggatcgcta cggacgggtg taaacgtcgc atcaggcgct gtttgtcgga tgcggcgtga
    68161 acgccttatc cgacctacgg ttcggatttg taggcctgat aagacgcggc agcgtcgcat
    68221 caggcaatga atgcgaaacc gagatgtaaa taacgacaaa aacaaaattg gccgtttcgg
    68281 tcagggccaa ctattgcctg aaaaagggta acgacatgaa aaaattaacc tgctttaaag
    68341 cctatgatat tcgcgggaaa ttaggcgaag aactgaatga agatattgcc tggcgcattg
    68401 ggcgtgccta tggcgaattt ctcaaaccga aaaccattgt gttaggcggt gatgtccgtc
    68461 tcaccagcga aaccttaaaa ctggcgctgg caaaaggttt acaggatgcg ggcgttgacg
    68521 tgctggatat cggtatgtcc ggcaccgaag agatctattt cgccacgttc catctcggcg
    68581 tggatggcgg cattgaagtt accgccagcc ataatccgat ggattataac ggcatgaagc
    68641 tggttcgcga gggggctcgc ccgatcagcg gagataccgg actgcgcgac gtccagcgtc
    68701 tggctgaagc caacgacttt cctcccgtcg atgaaaccaa acgcggtcgc tatcagcaaa
    68761 tcaacctgcg tgacgcttac gttgatcacc tgttcggtta tatcaatgtc aaaaacctca
    68821 cgccgctcaa gctggtgatc aactccggga acggcgcagc gggtccggtg gtggacgcca
    68881 ttgaagcccg ctttaaagcc cttggcgcac ccgtggaatt aatcaaagtg cacaacacgc
    68941 cggacggcaa tttccccaac ggtattccta acccgctact gccggaatgc cgcgacgaca
    69001 cccgcaatgc ggtcatcaaa cacggcgcgg atatgggcat tgcctttgat ggcgattttg
    69061 accgctgctt cctgtttgac gaaaaagggc agtttatcga aggctactac attgtcggcc
    69121 tgctggcaga agcgttcctc gaaaaaaatc ccggcgcgaa gatcatccac gatccacgtc
    69181 tctcctggaa taccgttgat gtggtgactg ccgctggcgg cacgccggtg atgtcgaaaa
    69241 ccggacacgc ctttattaaa gaacgtatgc gcaaggaaga cgccatctac ggtggcgaaa
    69301 tgagcgctca ccattacttc cgtgatttcg cttactgcga cagcggcatg atcccgtggc
    69361 tgctggtcgc cgaactggtg tgcctgaaag gaaaaacgct gggcgaactg gtgcgcgacc
    69421 ggatggctgc gtttccggca agcggtgaga tcaacagcaa actggcgcaa cccgttgagg
    69481 cgattaatcg cgtcgaacag cattttagcc gtgaggcgct ggcggtggat cgtaccgatg
    69541 gcatcagcat gacctttgcc gactggcgct ttaacctgcg cacctccaac accgaaccgg
    69601 tggtgcggtt gaatgtggaa tcgcgcggtg atgtgccgct gatggaagcg cgaacgcgaa
    69661 ctctgctgac gttgctgaat gagtaatgtc ggatcttccc ttaccccact gcgggtaagg
    69721 ggctaataac aggaacaacg atgacaaatc taaaaaagcg cgagcgagcg aaaaccaatg
    69781 catcgttaat ctctatggtg caacgctttt cagatatcac catcatgttt gccggactat
    69841 ggctggtttg cgaagtcagc ggactgtcat tcctctacat gcacctgttg gtggcgctga
    69901 ttacgctggt ggtgttccag atgctgggcg gcatcaccga tttttatcgc tcatggcgcg
    69961 gtgttcgggc agcgacagaa tttgccctgt tgctacaaaa ctggacctta agcatgattt
    70021 tcagcgccgg actggtggcg ttcaacaatg atttcgacac gcaactgaaa atctggctgg
    70081 cgtggtatgg gctgaccagt atcggactgg tggtttgccg ttcatgtatt cgtattgggg
    70141 cgggctggct gcgtaatcat ggctataaca agcgcatggt cgccgtagcg ggggatttag
    70201 ccgccggaca aatgctgatg gagagcttcc gtaatcagcc gtggttaggg tttgaagtgg
    70261 tgggcgttta ccacgacccg aaaccgggcg gcgtttctaa cgactgggcg ggcaatctgc
    70321 aacagctggt cgaggatgct aaagcgggca agattcataa cgtctatatc gcgatgcaaa
    70381 tgtgcgacgg cgcgcgagtg aaaaaactgg tccatcaact ggcggacacc acctgttcgg
    70441 tgctgctgat ccccgatgtc tttaccttca atattctcca ttcacgtctc gaagagatga
    70501 acggcgttcc ggtggtgccg ctgtatgaca cgccgctttc cggggttaac cgcctgctaa
    70561 aacgtgcgga agacattgtg ctggcgacgc ttatcctgct gctgatctcc ccggtgctgt
    70621 gctgcattgc gctggcggtg aaactcagtt cacctgggcc ggttattttc cgccagactc
    70681 gctacggcat ggatggcaag ccgatcaaag tgtggaagtt ccgttccatg aaagtgatgg
    70741 agaacgacaa agtggtgacc caggcgacgc agaacgatcc gcgcgtcact aaagtgggga
    70801 actttctgcg ccgcacctcg ctggacgaat tgccgcagtt tatcaatgtg ctgaccgggg
    70861 ggatgtcgat tgtcggtcca cgtccacacg cggtggcgca taacgaacag tatcgccagc
    70921 tcattgaagg ctacatgctg cgtcataaag tgaaacccgg cattaccggc tgggcgcaga
    70981 ttaatggctg gcgcggcgaa accgacacgc tggagaaaat ggaaaaacgc gtcgagttcg
    71041 accttgagta catccgcgaa tggagcgtct ggttcgatat caaaatcgtt ttcctgacgg
    71101 tattcaaagg cttcgttaac aaagcggcat attgatatga gcttacgtga aaaaaccatc
    71161 agcggcgcga agtggtcggc gatagccacg gtgatcatca tcggcctcgg gctggtgcag
    71221 atgaccgtgc tggcgcggat tatcgacaac caccagttcg gtttgcttac cgtgtcgctg
    71281 gtgatcatcg cgctggcaga tacgctttct gacttcggta tcgctaactc gattattcag
    71341 cgaaaagaaa tcagccacct tgaactcacc acgctgtact ggctgaacgt cgggctgggg
    71401 cttgtggtgt gcgtggcggt gtttttgttg agtgatgcca ttggcgacgt gctgaataac
    71461 ccggacctgg caccgttgat taaaacattg tcgctggcgt ttgtggtgat cccccacggg
    71521 caacagttcc gcgcgttgat gcagaaggag ctggagttca acaaaatcgg catgatcgaa
    71581 accagcgcgg tactggcggg cttcactttt acggtggtta gcgcccattt ctggccgctg
    71641 gcgatgaccg cgatcctcgg ttatctggtc aatagtgcag taagaacgct gctgtttggt
    71701 tactttggcc gcaaaattta tcgccccggt ctgcatttct cgctggcgtc ggtggcaccg
    71761 aacttacgtt ttggtgcctg gctgacggcg gacagcatca tcaactatct caataccaac
    71821 ctttcaacgc tggtgctggc gcgtattctc ggcgcgggcg tggcaggggg atacaacctg
    71881 gcgtacaacg tggccgttgt gccgccgatg aagctgaacc caatcattac ccgcgtgttg
    71941 tttccggcat ttgccaaaat tcaggacgac accgaaaagc tgcgcgttaa cttctacaag
    72001 ctgttgtcgg tagtggggat tatcaacttt ccggcgctgc tggggctgat ggtggtgtcg
    72061 aataactttg taccgctggt ctttggtgag aagtggaaca gcattattcc ggtgctgcaa
    72121 ttgctgtgtg tggtgggtct gctgcgctcc gtaggtaacc cgattggttc gctgctgatg
    72181 gcgaaagcgc gggtcgatat cagctttaaa ttcaacgtat tcaaaacatt tctgtttatt
    72241 ccggcgattg ttataggtgg gcagatggcg ggcgcgatcg gcgtcacgct tggcttcctg
    72301 ctggtgcaaa ttatcaacac cattctgagt tacttcgtga tgattaaacc ggttcttggt
    72361 tccagttatc gtcagtacat cctgagtttg tggctgccgt tttacctctc gctgccgacg
    72421 ctgggggtca gttatgcgct gggcattgtg ctgaaagggc aattggcgct ggggatgctg
    72481 ctggcggtgc aaatagccgc gggcgtgctg gcgtttgtgg tgatgattgt gctgtcgcgc
    72541 catccgctgg tggtggaagt gaagcgtcag ttttgtcgca gcgaaaaaat gaaaatgctt
    72601 ttacgggcgg ggtgagttgc tgttttcggt tccgacaacg gttgccggat gcggcgtaaa
    72661 acgccttatc cgtcctacgg ttctgtgctc gggacctgta ggcctgataa gacgcgtcag
    72721 cgtcgcatca ggcactgaat gccggatgcg gcgtgaacgc cttatccggc ctacggttca
    72781 gggcttggat cttgtggccc gataagacgc gccagcgtcg catcaggcac tgaatgccgg
    72841 atgcggcgta aaacgcctta tccggcctac ggttctgtgc tcgggtcttg taggcctgat
    72901 aagacgcgcc agcgtcgcat caggcactga atgccggatg cagcgtaaaa cgccttatcc
    72961 atcctacggt tctgtgctcg ggacttgtag gcctgataag acgcgccagc gtcgcatcag
    73021 gcactgaa
//
LOCUS       DAZUDJ010000017        72392 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.017, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000017 DAZUDJ010000000
VERSION     DAZUDJ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 72392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72392
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.017"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(206..1306)
                     /gene="chaA"
                     /locus_tag="ACHY1N_001600"
     CDS             complement(206..1306)
                     /gene="chaA"
                     /locus_tag="ACHY1N_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HFS4043930.1"
                     /translation="MSNAQEAVKTRHKETSLIFPVLALVVLFLWGSSQTLPVVIAINL
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPAANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFVYEHEDDSDDDDPHHGKPSAH
                     SSVWHAIWLIIHLIAVIAVTKMNASPLETLLDSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAFMTGNELQFALGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAHLALFAAYLMTIFA"
     gene            1576..1806
                     /gene="chaB"
                     /locus_tag="ACHY1N_001601"
     CDS             1576..1806
                     /gene="chaB"
                     /locus_tag="ACHY1N_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HFS4043931.1"
                     /translation="MPYKTKSDLPESVKHVLPSHAQDIYKEAFNSAWDQYKDKDDRRD
                     DASREETAHKVAWAAVKHEYAKGDDDKWHKKS"
     gene            1964..2659
                     /gene="chaC"
                     /locus_tag="ACHY1N_001602"
     CDS             1964..2659
                     /gene="chaC"
                     /locus_tag="ACHY1N_001602"
                     /EC_number="4.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-specific
                     gamma-glutamylcyclotransferase"
                     /protein_id="HFS4043932.1"
                     /translation="MITRDFLMNADCKTAFGAIEESLLWSAEQRAASLAATLACRPDE
                     GPVWIFGYGSLMWNPALEFTESCTGTLVGWHRAFCLRLTAGRGTAHQPGRMLALKEGG
                     RTTGVAYRLPEETLEQELTLLWKREMITGCYLPTWCQLDLDDGCTVNAIVFIMDPRHP
                     EYESDTRAQVIAPLIAAASGPLGTNAQYLFSLEQELIKLGMQDDGLNDLLVSVKKLLA
                     ENYPDGVLRPGFA"
     gene            complement(2703..3056)
                     /gene="ychN"
                     /locus_tag="ACHY1N_001603"
     CDS             complement(2703..3056)
                     /gene="ychN"
                     /locus_tag="ACHY1N_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/F sulfur relay family protein YchN"
                     /protein_id="HFS4043933.1"
                     /translation="MQKIVIVANGAPYGSESLFNSLRLAIALREQESNLDLRLFLMSD
                     AVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTHPLIDGVEIGTLV
                     ELAQWTLSADKVLTF"
     gene            3241..4635
                     /gene="ychO"
                     /locus_tag="ACHY1N_001604"
                     /gene_synonym="iatA"
     CDS             3241..4635
                     /gene="ychO"
                     /locus_tag="ACHY1N_001604"
                     /gene_synonym="iatA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter invasin YchO"
                     /protein_id="HFS4043934.1"
                     /translation="MSRFVPRIIPFYLLLLVAGGTANAQSTFEQKAANPFDNNNDGLP
                     DLGMAPENHDGEKHFAEIVKDFGETSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHV
                     ESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLGLTQQDDGLVSNV
                     GVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQT
                     ATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDRVDLFNSGTGYHNPVALSLGL
                     NYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKKQLSAGEVAESQSLRGSRY
                     DNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQGDTQ
                     ILSLTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVE
                     PFDALSNDELRWEP"
     gene            complement(4636..5286)
                     /gene="narL"
                     /locus_tag="ACHY1N_001605"
     CDS             complement(4636..5286)
                     /gene="narL"
                     /locus_tag="ACHY1N_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HFS4043935.1"
                     /translation="MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQG
                     IELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF"
     gene            complement(5279..7075)
                     /gene="narX"
                     /locus_tag="ACHY1N_001606"
     CDS             complement(5279..7075)
                     /gene="narX"
                     /locus_tag="ACHY1N_001606"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HFS4043936.1"
                     /translation="MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGL
                     QDYWRNELIPALIRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMA
                     VFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNN
                     MSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQ
                     NLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRL
                     ADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLT
                     TFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALS
                     NALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGD
                     CRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE"
     gene            7414..8805
                     /gene="narK"
                     /locus_tag="ACHY1N_001607"
     CDS             7414..8805
                     /gene="narK"
                     /locus_tag="ACHY1N_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HFS4043937.1"
                     /translation="MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGR
                     RWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWI
                     WVPFLAIFTIAAWFGMNDLATSKASIKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGL
                     LFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKK"
     gene            9321..13064
                     /gene="narG"
                     /locus_tag="ACHY1N_001608"
     CDS             9321..13064
                     /gene="narG"
                     /locus_tag="ACHY1N_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009325 - nitrate reductase complex
                     [Evidence IEA];
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HFS4043938.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIG
                     FRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELEN
                     VLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWA
                     EQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVD
                     YTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQ
                     GKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVMGQKSNGNPEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLGIADNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAH
                     LAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK"
     gene            13061..14599
                     /gene="narH"
                     /locus_tag="ACHY1N_001609"
     CDS             13061..14599
                     /gene="narH"
                     /locus_tag="ACHY1N_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009325 - nitrate reductase complex
                     [Evidence IEA];
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HFS4043939.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNV
                     ETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYE
                     PFDFDYQNLHTAPEGSKAQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKN
                     FDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCR
                     GWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYD
                     ADAIERAASTENEKDLYQRQLDVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMA
                     MEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLAN
                     LLTAGDTKPVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIA
                     NYEDRFVVPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKT
                     EPHP"
     gene            14596..15306
                     /gene="narJ"
                     /locus_tag="ACHY1N_001610"
     CDS             14596..15306
                     /gene="narJ"
                     /locus_tag="ACHY1N_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0051131 - chaperone-mediated protein
                     complex assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HFS4043940.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQEMFEAIAASENLSKEDAHALG
                     IFLRDLTALDPLDAQAQYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLLAQYEQHG
                     LQLNSRELPDHLPLYLEYLAQLPQSEAVEGLKDIAPILALLSARLQQRESRYAVLFDL
                     LLKLANTAIDSDKVAEKIADEARDDTPQALDAVWEEEQVKFFADKGCGDSAITAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            15306..15983
                     /gene="narI"
                     /locus_tag="ACHY1N_001611"
     CDS             15306..15983
                     /gene="narI"
                     /locus_tag="ACHY1N_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009325 - nitrate reductase complex
                     [Evidence IEA];
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HFS4043941.1"
                     /translation="MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAWLPIEVKQKMAMFAGGASGVLCL
                     IGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QLVRARH"
     gene            complement(16167..16298)
                     /locus_tag="ACHY1N_001612"
     ncRNA           complement(16167..16298)
                     /ncRNA_class="other"
                     /locus_tag="ACHY1N_001612"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(16345..16476)
                     /locus_tag="ACHY1N_001613"
     ncRNA           complement(16345..16476)
                     /ncRNA_class="other"
                     /locus_tag="ACHY1N_001613"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(16524..16608)
                     /locus_tag="ACHY1N_001614"
     tRNA            complement(16524..16608)
                     /locus_tag="ACHY1N_001614"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16572..16574),aa:Tyr,seq:gta)
     gene            complement(16768..17610)
                     /gene="purU"
                     /locus_tag="ACHY1N_001615"
     CDS             complement(16768..17610)
                     /gene="purU"
                     /locus_tag="ACHY1N_001615"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008864 - formyltetrahydrofolate
                     deformylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HFS4043942.1"
                     /translation="MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLSRNEHDQKMADAIDAYQ
                     PDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNR
                     TIIL"
     gene            complement(17660..18118)
                     /gene="ychJ"
                     /locus_tag="ACHY1N_001616"
     CDS             complement(17660..18118)
                     /gene="ychJ"
                     /locus_tag="ACHY1N_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HFS4043943.1"
                     /translation="MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQ
                     DADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTE
                     GGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ"
     gene            18231..19136
                     /gene="rssA"
                     /locus_tag="ACHY1N_001617"
     CDS             18231..19136
                     /gene="rssA"
                     /locus_tag="ACHY1N_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004622 - lysophospholipase activity
                     [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HFS4043944.1"
                     /translation="MRKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGS
                     LVGAAYACDRLSALEDWVTSFSYWDVLRLMDLSWQRGGLLRGERVFNQYREIMPETEI
                     ENCSRRFAAVATNLSTGRELWFTEGDLHLAIRASCSIPGLMAPVAHNGYWLVDGAVVN
                     PIPISLTRALGADIVIAVDLQHDAHLMQQDLLSFNVSEENSENGDSLPWHARLKERLG
                     SITTRRAVTAPTATEIMTTSIQVLENRLKRNRMAGDPPDILIQPVCPQISTLDFHRAH
                     AAIAAGQLAVERKMDELLPLVRTNI"
     gene            19228..20241
                     /gene="rssB"
                     /locus_tag="ACHY1N_001618"
     CDS             19228..20241
                     /gene="rssB"
                     /locus_tag="ACHY1N_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HFS4043945.1"
                     /translation="MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDAL
                     ELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
                     QPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALL
                     LRALFNGLLQEQLAHQNQRLPELGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLI
                     LVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLML
                     SAE"
     gene            20443..21351
                     /gene="galU"
                     /locus_tag="ACHY1N_001619"
     CDS             20443..21351
                     /gene="galU"
                     /locus_tag="ACHY1N_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFS4043946.1"
                     /translation="MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNTLGTEFKAWLEEEMGIKK"
     gene            complement(21495..21908)
                     /gene="hns"
                     /locus_tag="ACHY1N_001620"
     CDS             complement(21495..21908)
                     /gene="hns"
                     /locus_tag="ACHY1N_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0071824 - protein-DNA complex organization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histone-like nucleoid-structuring protein H-NS"
                     /protein_id="HFS4043947.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ"
     gene            22513..23130
                     /gene="tdk"
                     /locus_tag="ACHY1N_001621"
     CDS             22513..23130
                     /gene="tdk"
                     /locus_tag="ACHY1N_001621"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFS4043948.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNSSLFDEIRAEHEQQAIHCVLVDECQFLTRQQVYELSE
                     VVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQA
                     GRPYNEGEQVVIGGNERYVSVCRKHYKEALQVGSLTAIQERHRHD"
     gene            complement(23432..26107)
                     /gene="adhE"
                     /locus_tag="ACHY1N_001622"
                     /gene_synonym="adhC"
     CDS             complement(23432..26107)
                     /gene="adhE"
                     /locus_tag="ACHY1N_001622"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFS4043949.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQG
                     KELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLL
                     KEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDYVEGETAAKKEAAPAKAEKKAKKSA"
     gene            26500..26553
                     /gene="ychE"
                     /locus_tag="ACHY1N_001623"
     CDS             26500..26553
                     /gene="ychE"
                     /locus_tag="ACHY1N_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YchT"
                     /protein_id="HFS4043950.1"
                     /translation="MLSKGVLSARLFNLIYG"
     gene            26584..27231
                     /gene="ychE"
                     /locus_tag="ACHY1N_001624"
     CDS             26584..27231
                     /gene="ychE"
                     /locus_tag="ACHY1N_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YchE"
                     /protein_id="HFS4043951.1"
                     /translation="MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARN
                     KTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
                     ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN"
     gene            complement(27389..27685)
                     /locus_tag="ACHY1N_001625"
     CDS             complement(27389..27685)
                     /locus_tag="ACHY1N_001625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043952.1"
                     /translation="MRFLLANTFCKIVKQFSFIDRIRIYSLHPCLNKHLSIQSNRDWL
                     SMSIFSDYSSSSEMHNNLTIDYYLALSSTKGSGITNIISIILQQAQDYDVAKIT"
     gene            27969..29600
                     /gene="oppA"
                     /locus_tag="ACHY1N_001626"
     CDS             27969..29600
                     /gene="oppA"
                     /locus_tag="ACHY1N_001626"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HFS4043953.1"
                     /translation="MTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRN
                     NGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHL
                     RKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDL
                     GVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYT
                     LKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA
                     QGDMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYN
                     TSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEARRTALYTKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH"
     gene            29686..30606
                     /gene="oppB"
                     /locus_tag="ACHY1N_001627"
     CDS             29686..30606
                     /gene="oppB"
                     /locus_tag="ACHY1N_001627"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HFS4043954.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPE
                     VMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGA
                     AAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHW
                     LPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            30621..31529
                     /gene="oppC"
                     /locus_tag="ACHY1N_001628"
     CDS             30621..31529
                     /gene="oppC"
                     /locus_tag="ACHY1N_001628"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HFS4043955.1"
                     /translation="MMLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLI
                     VLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGR
                     ISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF
                     GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNV
                     LGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPA
                     GFLVVTLFCFNFIGDGLRDALDPKDR"
     gene            31541..32554
                     /gene="oppD"
                     /locus_tag="ACHY1N_001629"
     CDS             31541..32554
                     /gene="oppD"
                     /locus_tag="ACHY1N_001629"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP-binding protein OppD"
                     /protein_id="HFS4043956.1"
                     /translation="MSVIETATVPLAQQQADALLNVKDLRVTFSTPDGDVTAVNDLNF
                     SLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNGREILNLPEHELNKLR
                     AEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKNMSKAEAFEESVRMLDAVKMPEARK
                     RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREF
                     NTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPVHPYSIGLLNAVPRLD
                     AEGETMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEEFTPGRLRACFKPVE
                     ELL"
     gene            32551..33555
                     /gene="oppF"
                     /locus_tag="ACHY1N_001630"
     CDS             32551..33555
                     /gene="oppF"
                     /locus_tag="ACHY1N_001630"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP-binding protein OppF"
                     /protein_id="HFS4043957.1"
                     /translation="MNAVTEGRKVLLEIADLKVHFEIKDGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGHVAWLGKELLGMKPDEWRAVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKMSRQEVRERVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTRALMSAVPIPDPDLE
                     KNKTIQLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            complement(33608..33937)
                     /gene="yciU"
                     /locus_tag="ACHY1N_001631"
     CDS             complement(33608..33937)
                     /gene="yciU"
                     /locus_tag="ACHY1N_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309775.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI1450 family dsDNA-mimic protein"
                     /protein_id="HFS4043958.1"
                     /translation="MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKL
                     CHIIWRE"
     gene            complement(33972..35432)
                     /gene="cls"
                     /locus_tag="ACHY1N_001632"
     CDS             complement(33972..35432)
                     /gene="cls"
                     /locus_tag="ACHY1N_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFS4043959.1"
                     /translation="MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAP
                     LFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQ
                     DDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL"
     gene            35575..35748
                     /gene="yciY"
                     /locus_tag="ACHY1N_001633"
     CDS             35575..35748
                     /gene="yciY"
                     /locus_tag="ACHY1N_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HFS4043960.1"
                     /translation="MKRSRTEVGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILN
                     KQRNSLLFAIYNI"
     gene            complement(35803..37056)
                     /gene="kch"
                     /locus_tag="ACHY1N_001634"
     CDS             complement(35803..37056)
                     /gene="kch"
                     /locus_tag="ACHY1N_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated potassium channel protein"
                     /protein_id="HFS4043961.1"
                     /translation="MSHWATFKQTATNLWVTLRHDILALAVFLNGLLIFKTIYGMSVN
                     LLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIY
                     TLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
                     LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMT
                     SIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLP
                     EDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKD
                     MSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLL
                     NSGHGIFSDNDEQETKADSKESAQK"
     gene            complement(37356..37652)
                     /gene="yciI"
                     /locus_tag="ACHY1N_001635"
     CDS             complement(37356..37652)
                     /gene="yciI"
                     /locus_tag="ACHY1N_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HFS4043962.1"
                     /translation="MLYVIYAQDKADSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKVF"
     gene            complement(38322..38864)
                     /locus_tag="ACHY1N_001636"
     CDS             complement(38322..38864)
                     /locus_tag="ACHY1N_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4043963.1"
                     /translation="MANIGYIRVSSIQQITDRQLEGVVLDKVFTDKASGKNTDRPQLK
                     AMLDYVREGDVIHVHDLSRLGRSTVDVLTLVDKLSQKGIKVHFYKEGLITGDDNPTSK
                     MILTIFSAVAEAERKMMLERQREGYEAAKAAGRVVGRGNGKAIDREGIKAALAAGSSI
                     AKVAAQFNVAKSTVQRIKAE"
     gene            complement(40485..40673)
                     /locus_tag="ACHY1N_001637"
     CDS             complement(40485..40673)
                     /locus_tag="ACHY1N_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043964.1"
                     /translation="MVNLPPELGSPDVWAGGGIGLIAGLLLRYFIVRVFIVFRLFGRE
                     WSFDLKDRTRTDNHTEPR"
     gene            40903..41460
                     /locus_tag="ACHY1N_001638"
     CDS             40903..41460
                     /locus_tag="ACHY1N_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001685060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043965.1"
                     /translation="MRDAEFRAMLQASKERNKHNSYAYTNNPTSYELPKFTKKERKGI
                     DEVIRAITPRSRYMPTRKSTKNTIKNYLANFDSYEQLPSKLDDVIIGFCRSEGHPKYN
                     RKLFYILKNLDEINSATVTNHLQRQATRLSYELPSDKYCALLAVMCAKLIGIVEHHIA
                     VGNIEPMENEQPDFEFDPYLVTEEF"
     gene            41461..41739
                     /locus_tag="ACHY1N_001639"
     CDS             41461..41739
                     /locus_tag="ACHY1N_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043966.1"
                     /translation="MNKHTLTRISEEAFNELNRIKRATNLPHQTVMQLAIAKEVTESD
                     LLKYPVSKGRKHIRITTDALDTLKALNSFKIDIARLLSIKIHKLSMGV"
     gene            41739..41954
                     /locus_tag="ACHY1N_001640"
     CDS             41739..41954
                     /locus_tag="ACHY1N_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000882843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043967.1"
                     /translation="MLCVTFEYHTDKMIRYISDLLIKGNGFGDIHNSKDIFIKAIGPN
                     ETLKTAVKPEWFERHKIELGYWGEEVL"
     gene            41951..42238
                     /locus_tag="ACHY1N_001641"
     CDS             41951..42238
                     /locus_tag="ACHY1N_001641"
                     /inference="COORDINATES: protein motif:HMM:NF024784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFS4043968.1"
                     /translation="MKPWHEDVRRYFTEHLIYDESSDSLCWSDGESVTINTDDYGNKT
                     FNIGRYTFYVKYVVWFLYHGYQSNKQIIHRNGNRADTRPKNLMQVRDFKRN"
     gene            42394..42717
                     /locus_tag="ACHY1N_001642"
     CDS             42394..42717
                     /locus_tag="ACHY1N_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043969.1"
                     /translation="MNNYELQIFIDTDTAMMIQAFTDVGVSIDFDKLLELMTDNAESI
                     SDFIQSVEFNEPRMMLPIKDSNMKRLVIEQTNKYSVSPEKYLKAAIAILYSDNILVTD
                     SKVVH"
     gene            43275..43985
                     /locus_tag="ACHY1N_001643"
     CDS             43275..43985
                     /locus_tag="ACHY1N_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001502266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4043970.1"
                     /translation="MTNDIYINGKVIDSFGDWSPQGEHPLHTIQRQEHDKRIELEQSL
                     KMSPKEIIFVTPEPQEMPDICKSEALLELEKKYYPLLKAQRIKLDIAYDNVKNFEETE
                     KPTDFDIEVEIRQNPFVYYSVEDNDGFGTARENISKVLQNIPEGFRLIDVRPASRGTG
                     SYILLSDKTDEEICQLAEKNLLERHSKKLNRFKQELANQLRAMKQLISDYETQKKIAM
                     QADIEQLTKISSKYAKAI"
     gene            44004..44222
                     /locus_tag="ACHY1N_001644"
     CDS             44004..44222
                     /locus_tag="ACHY1N_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001502265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4043971.1"
                     /translation="MIDLQQRYEVIKSVCESLKLQPNKPKLRIKSKRQIITSHKPKVR
                     RIPSWCIDRVPADAQLIGESGSYTYILH"
     gene            44306..46378
                     /locus_tag="ACHY1N_001645"
     CDS             44306..46378
                     /locus_tag="ACHY1N_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFS4043972.1"
                     /translation="MAQFKVDDFLIELSFSSQKVLKGLEKAEKQTMQIASRIEKRLNK
                     AFKVNPTPLNDSLKLMEKNVDKTVSKIEQRFKNTKAFKIKTEIEDTLKPLRQPRQPRI
                     SGNRAITAAYSANMSKLKGFDPILQKYIKSQFYGLSAKAGSMDNSKFNERLAQLNASV
                     REAITKARGHTSTSKNNHSENASNGLDVLATSAIKAGTAIYSFQTALEAYRKIMEVGL
                     KKEASQRAAQFVLGDEGAKRATEFVKNLADSSGVDQIETLSSFAKFSAGAGDMNTDQK
                     ESLFSNVIGTSRLMGLSTDEINGILKAFEQMASKGKIQAEELRGQLGDRMAGAFQLFA
                     RSLGMTTEQLDAAMKNGKVLSKDVLPKVSAEMGRMIDKAGGWEKIINSTQTQLGRLSN
                     SWNNNMALMFDGSQEGLTDFTRSLTNLLNSLGGQSKNLGEHFGDLMKSMSNGIDDLTT
                     ISYRVQGFFDRVTLAYRELNDTQKAVADGIANGLLSALKGLAGIVAVRSGIGAVGGIW
                     NLIRAISTLGNVANTAAGRINSRSGSVEGGKGKLSVADAITRVMIVGMATDVINSIVK
                     PFYERQMSKSDNPIDKIVRSKVEPTDQALTGDMNSLAAVLWAMVQGKSKDVPQFSPEA
                     LNNLKGRVETFTQDLKVIKPSVNIQPQTINITTQTVLDGKVIDERTTSHINRMQEDTL
                     ISSAYPEE"
     gene            46613..47386
                     /locus_tag="ACHY1N_001646"
     CDS             46613..47386
                     /locus_tag="ACHY1N_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HFS4043973.1"
                     /translation="MIYTNQIKYSGKDGIYFHLRDNVDAFLTLSATENMEFDSPMQVT
                     TQNMQSGQTVTDNVMRSPRTISISGVVVVGYEGSLLLTRQGQLVENFIDTLESWRDQK
                     QIISVICKDGIKIDDSIITSFKASKDVGISNGLRIQLTFQEINFKAIVGQTDISAATG
                     KAATTNDGGATSKKNAGNVTTERNNAPMLMCQELYSYSASELSDEALRVRSNCSKNVT
                     VKDGVSTFTDAANEQASKVLKSGNALRKFSVNPNKKGTY"
     gene            complement(47419..48939)
                     /locus_tag="ACHY1N_001647"
     CDS             complement(47419..48939)
                     /locus_tag="ACHY1N_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4043974.1"
                     /translation="MRTVITYLRFSSAIQGAEGADSTRRQNDLFKQWLKKNSDAQVVA
                     SFSDEGLSGYKGKHLTGQFGDMLARIESGEFPEGTILLVEAIDRIGRLEHLETEALMN
                     RIIAHGIEIHTLQDGLIYTRDALSDDLGISIIQRVKSYVAHQESKQKSFRVSQKWKQR
                     AKLALAGEQRLTKMVPGWIDPDTFKCNEHAETVRLIFKLLLDGESLHNIARHLQANNI
                     SSFSRRKDANGFSVHSVRTILRSETTIGTLPASQRNDRPAIPNYYEAAIDAATFNKAQ
                     EILDKNRKGRTPASDNPLTINIFKGLFRCQCGASVHPTGTKNKYAGVYRCNNNPDGRC
                     DVPPLKRKPFDRWMIDNFLGMIDVGNDGESERKIAALQHEVEIVTARIKKATALLLEM
                     DDITELKAQVKGLNQKRTEIQTTIDALKRKTSLTDKELPQLKDIDLTTKAGRVECQLI
                     LSKHLKGLTLGKDSVTVTLQNDTEITIPTNPLPLNDGSPIFEIADKELLDIDAYQL"
     gene            49030..49749
                     /gene="tonB"
                     /locus_tag="ACHY1N_001648"
     CDS             49030..49749
                     /gene="tonB"
                     /locus_tag="ACHY1N_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HFS4043975.1"
                     /translation="MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQP
                     ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPAVIEKPKPKPKPKPKP
                     VKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQ
                     PQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPG
                     KPGSGIVVNILFKINGTTEIQ"
     gene            complement(49789..50187)
                     /gene="yciA"
                     /locus_tag="ACHY1N_001649"
     CDS             complement(49789..50187)
                     /gene="yciA"
                     /locus_tag="ACHY1N_001649"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HFS4043976.1"
                     /translation="MSTTHNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVQKGTTSVSINIEVWVKKVASE
                     PIGQRYKATEALFKYVAVDPEGKPRALPVE"
     gene            complement(50292..50831)
                     /gene="yciB"
                     /locus_tag="ACHY1N_001650"
     CDS             complement(50292..50831)
                     /gene="yciB"
                     /locus_tag="ACHY1N_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HFS4043977.1"
                     /translation="MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRF
                     RKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQ
                     RMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGIYIYRHMPQEDKS"
     gene            complement(50861..51604)
                     /gene="yciC"
                     /locus_tag="ACHY1N_001651"
     CDS             complement(50861..51604)
                     /gene="yciC"
                     /locus_tag="ACHY1N_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciC family protein"
                     /protein_id="HFS4043978.1"
                     /translation="MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPS
                     DAQLAQLNDGVPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVIL
                     IIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLAL
                     APVMLVQDKMGIFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEI
                     GAVLANTLSNLISAILLIYLFRLYMLIRQ"
     gene            complement(51632..51721)
                     /locus_tag="ACHY1N_001652"
                     /pseudo
     CDS             complement(51632..51721)
                     /locus_tag="ACHY1N_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            51961..52599
                     /gene="ompW"
                     /locus_tag="ACHY1N_001653"
     CDS             51961..52599
                     /gene="ompW"
                     /locus_tag="ACHY1N_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HFS4043979.1"
                     /translation="MKKLTVAALAVTTLLSGSAFAHEAGEFFMRAGSATVRPTEGAGG
                     TLGSLGGFSVTNNTQLGLTFTYMATDNIGVELLAATPFRHKIGTRATGDIATVHHLPP
                     TLMAQWYFGDASSKFRPYVGAGINYTTFFDNGFNDHGKEAGLSDLSLKDSWGAAGQVG
                     VDYLINRDWLVNMSVWYMDIDTTANYKLGGAQQHDSVRLDPWVFMFSAGYRF"
     gene            complement(52659..53165)
                     /gene="yciE"
                     /locus_tag="ACHY1N_001654"
     CDS             complement(52659..53165)
                     /gene="yciE"
                     /locus_tag="ACHY1N_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFS4043980.1"
                     /translation="MNRIEHYHDWLRDAHAMEKQAESMLESMASRIDNYPELRARIEQ
                     HLSETKNQIVQLETILDRNDISRSVIKDSMSKIAALGQSIGGIFPSDEIVKGSISGYV
                     FEQFEIACYTSLLAAAKNAGDTASIPTIEAILNEEKQMADWLIQHIPQTTEKFLIRSE
                     TDGVEAKK"
     gene            complement(53211..53711)
                     /gene="yciF"
                     /locus_tag="ACHY1N_001655"
     CDS             complement(53211..53711)
                     /gene="yciF"
                     /locus_tag="ACHY1N_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFS4043981.1"
                     /translation="MNMKTIEDVFIHLLSDTYSAEKQLTRALAKLARATSNEKLSQAF
                     HAHLEETHGQIERIDQVVESESNLKIKRMKCVAMEGLIEEANEVIESTEKNEVRDAAL
                     IAAAQKVEHYEIASYGTLATLAEQLGYRKAAKLLKETLEEEKATDIKLTDLALNNVNK
                     KAENKA"
     gene            complement(53797..53976)
                     /gene="yciG"
                     /locus_tag="ACHY1N_001656"
     CDS             complement(53797..53976)
                     /gene="yciG"
                     /locus_tag="ACHY1N_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309858.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HFS4043982.1"
                     /translation="MAEHRGGSGNFAEDREKASDAGRKGGQHSGGNFKNDPQRASEAG
                     KKGGQQSGGNKSGKS"
     gene            complement(54357..55163)
                     /gene="trpA"
                     /locus_tag="ACHY1N_001657"
     CDS             complement(54357..55163)
                     /gene="trpA"
                     /locus_tag="ACHY1N_001657"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HFS4043983.1"
                     /translation="MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAG
                     ADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMY
                     ANLVFNKGIDEFYAQCEKVGVDSVLVADVPIEESAPFRQAALRHNVAPIFICPPNADD
                     DLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPD
                     QVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS"
     gene            complement(55163..56356)
                     /gene="trpB"
                     /locus_tag="ACHY1N_001658"
     CDS             complement(55163..56356)
                     /gene="trpB"
                     /locus_tag="ACHY1N_001658"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HFS4043984.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQ
                     FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG
                     KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE
                     REGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALE
                     AFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK
                     AREEI"
     gene            complement(56368..57729)
                     /gene="trpCF"
                     /locus_tag="ACHY1N_001659"
     CDS             complement(56368..57729)
                     /gene="trpCF"
                     /locus_tag="ACHY1N_001659"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HFS4043985.1"
                     /translation="MMQTVLAKIVADKAIWVETRKQQQPLASFQNEVQPSTRHFYDAL
                     QGARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFDFLP
                     IVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMG
                     VLTEVSNEEELERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGI
                     NTYAQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAG
                     AIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQL
                     HGNEDQLYIDTLREALPAHVAIWKALSVGETLPARELQHVDKYVLDNGQGGSGQRFDW
                     SLLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTL
                     RAY"
     gene            complement(57730..59325)
                     /gene="trpD"
                     /locus_tag="ACHY1N_001660"
     CDS             complement(57730..59325)
                     /gene="trpD"
                     /locus_tag="ACHY1N_001660"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HFS4043986.1"
                     /translation="MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERL
                     ATMSNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPANTLQPILEKLYQAQTLSQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGHEDLQANA
                     QTVLEVLRSGSAYDRVTALAARG"
     gene            complement(59325..60887)
                     /gene="trpE"
                     /locus_tag="ACHY1N_001661"
     CDS             complement(59325..60887)
                     /gene="trpE"
                     /locus_tag="ACHY1N_001661"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HFS4043987.1"
                     /translation="MQTQKPTLELLTCEGAYRDNPTALFHQLCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSGNGEALLTLLDNALPAGVENEQLPNCRV
                     LRFPPVSPLLDEDARLCSLSVFDAFRLLQNLLNVPKEEREAMFFGGLFSYDLVAGFED
                     LPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFAPNEEEKQRLTARLNELRQQ
                     LTEAAPPLPVVSVPHMRCECNQSDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGR
                     RADGSLDRDLDSRIELEMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYG
                     GAVGYFTAHGDLDTCIVIRSALVENGIATVQAGAGVVLDSVPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     misc_feature    complement(60909..61002)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00513"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Trp leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00513"
     gene            complement(60979..61023)
                     /gene="trpL"
                     /locus_tag="ACHY1N_001662"
     CDS             complement(60979..61023)
                     /gene="trpL"
                     /locus_tag="ACHY1N_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HFS4043988.1"
                     /translation="MKAIFVLKGWWRTS"
     gene            61161..62042
                     /gene="rnm"
                     /locus_tag="ACHY1N_001663"
                     /gene_synonym="trpH"
                     /gene_synonym="yciV"
     CDS             61161..62042
                     /gene="rnm"
                     /locus_tag="ACHY1N_001663"
                     /gene_synonym="trpH"
                     /gene_synonym="yciV"
                     /EC_number="3.1.13.-"
                     /EC_number="3.1.3.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase AM"
                     /protein_id="HFS4043989.1"
                     /translation="MSDTNYAVIYDLHSHTTASDGCLTPEALVHRAVEMRVGTLAITD
                     HDTTAAIAPAREEISRSGLALNLIPGVEISTVWENHEIHIVGLNIDITHPLMCEFLAQ
                     QTERRNQRAQLIAERLEKAQIPGALEGAQRLAQGGAVTRGHFARFLVECGKASSMADV
                     FKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYNLSAKWLKRLVAHFAE
                     HHGDAMEVAQCQQSPNERTQLAALARQHHLWASQGSDFHQPCPWIELGRKLWLPAGVE
                     GVWQLWEQPQNTTEREL"
     gene            62039..62659
                     /gene="yciO"
                     /locus_tag="ACHY1N_001664"
     CDS             62039..62659
                     /gene="yciO"
                     /locus_tag="ACHY1N_001664"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFS4043990.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKI
                     EDKNAMERICRIRQLPDGHNFTLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL"
     gene            62760..63632
                     /gene="rluB"
                     /locus_tag="ACHY1N_001665"
     CDS             62760..63632
                     /gene="rluB"
                     /locus_tag="ACHY1N_001665"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HFS4043991.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEV
                     TPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QVSGGRRSGGRNNG"
     gene            complement(63672..64262)
                     /gene="cobO"
                     /locus_tag="ACHY1N_001666"
     CDS             complement(63672..64262)
                     /gene="cobO"
                     /locus_tag="ACHY1N_001666"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HFS4043992.1"
                     /translation="MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTA
                     AFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDT
                     AACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
                     RGCHRDILELADTVSELRPIKHAFDAGVKAQIGIDY"
     gene            complement(64259..65017)
                     /gene="yciK"
                     /locus_tag="ACHY1N_001667"
     CDS             complement(64259..65017)
                     /gene="yciK"
                     /locus_tag="ACHY1N_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HFS4043993.1"
                     /translation="MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGR
                     NEEKLRQVASHINEETGRQPQWFILDLLTCTSEDCQQLAQRITVNYPRLDGVLHNAGL
                     LGDVCPMSEQNPQVWQDVIQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPA
                     DIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGISQ"
     gene            65237..66286
                     /gene="sohB"
                     /locus_tag="ACHY1N_001668"
     CDS             65237..66286
                     /gene="sohB"
                     /locus_tag="ACHY1N_001668"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HFS4043994.1"
                     /translation="MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRV
                     NNLSEQYKEMKEELAAALMDSHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVATDSKPR
                     VWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQR
                     LRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKD
                     IDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVAT
                     GEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESAD
                     RLLLRWWQRGQKPLM"
     gene            complement(66322..66573)
                     /gene="yciN"
                     /locus_tag="ACHY1N_001669"
     CDS             complement(66322..66573)
                     /gene="yciN"
                     /locus_tag="ACHY1N_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HFS4043995.1"
                     /translation="MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLV
                     FTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            66953..69550
                     /gene="topA"
                     /locus_tag="ACHY1N_001670"
     CDS             66953..69550
                     /gene="topA"
                     /locus_tag="ACHY1N_001670"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFS4043996.1"
                     /translation="MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNID
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEVDASTTTPSGGALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPT
                     TSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRIL
                     PAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDH
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     PPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYV
                     DGKWVEGKK"
     gene            69760..70734
                     /gene="cysB"
                     /locus_tag="ACHY1N_001671"
     CDS             69760..70734
                     /gene="cysB"
                     /locus_tag="ACHY1N_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HFS4043997.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVM
                     LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIKLPEK"
     gene            71053..71193
                     /gene="ymiA"
                     /locus_tag="ACHY1N_001672"
     CDS             71053..71193
                     /gene="ymiA"
                     /locus_tag="ACHY1N_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588449.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HFS4043998.1"
                     /translation="MRLAMPSGNQEPRRDPELKRKAWLAVFLGSALFWVVVALLIWKV
                     WG"
     gene            71196..71363
                     /gene="yciX"
                     /locus_tag="ACHY1N_001673"
     CDS             71196..71363
                     /gene="yciX"
                     /locus_tag="ACHY1N_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YciX"
                     /protein_id="HFS4043999.1"
                     /translation="MVGQEQLESSPLCQHSDNETETKRECSVVIPDDWQLTSQQQAFI
                     ELFAEDDQPKQ"
     gene            71477..71572
                     /gene="ymiC"
                     /locus_tag="ACHY1N_001674"
     CDS             71477..71572
                     /gene="ymiC"
                     /locus_tag="ACHY1N_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small membrane protein YmiC"
                     /protein_id="HFS4044000.1"
                     /translation="MINTNMKYWSWMGAFSLSMLFWAELLWIITH"
     gene            71736..>72392
                     /locus_tag="ACHY1N_001675"
     CDS             71736..>72392
                     /locus_tag="ACHY1N_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitase family protein"
                     /protein_id="HFS4044001.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSLKV
                     LLENLLRWQDGNSVTEEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMI
                     N"
BASE COUNT        18921 a        16877 c        17971 g        18623 t
ORIGIN      
        1 ctcaattcat cttcacttca tccctgaaat gtttgcaata aagagtacat tccggctttt
       61 caacagctgt tgcagtggtt tcgtgcaggt tgtggtacag gctcgcaatt ctgattaacg
      121 agctgtccag gtagtatgaa gaaatacaat aagcaggaat ttatcttatc tcccccgatt
      181 tccgtcatcg gaggagatat aactgtcagg caaatatcgt catcaaatag gcggcaaaca
      241 gtgccagatg cgctgcgcca ttgagcacgt tagtacgtcc ggtggagaag gagatatggc
      301 acagcactaa agaggccacc atcaccacca tttctggcgc accaagtgca aactgtaatt
      361 cgttacccgt cataaaggca attagcgtga cgacaggtac ggtaagcgaa atggttgcta
      421 acactgaacc aaagaacaga ttcatcgcgc gctggacctg gttgttcaac actgctttta
      481 acgcacctaa accttccggc gacagaatca acagagccac caggaagcca gtaaaggcga
      541 caggggcatt catgctgtcg agcaatgtct ccagcgggct ggcattcatt ttggtgactg
      601 caataacggc aatcagatgg ataatcaacc agatagcatg ccacacgctg ctatgggcag
      661 acggtttacc gtgatgcggg tcatcgtcat cactgtcatc ttcgtgctcg tagacaaaca
      721 aactttgatg cgttttggtc tggatcagca aaaatacgcc atacattgcc gcagaaatta
      781 atgctaccag taacgcctga ccggttgaaa aattcgccgc aggcagagcc attggaaata
      841 ccagtacgat tatcgccagg gggaacagcg caattaaata ctgcttgata ccaaacagat
      901 tcatatattg ggtggcaaac ttacgaccgc ccaacaataa tgaaaagcca accagcccac
      961 cggtaacaat cataatgatt gaatagagcg tatcacgcat tagcgttggc gcggcgtcgc
     1021 cggttgccat taaagctgaa atcaaactga cttcaagaat aaccactgaa aggctaagaa
     1081 taagcgaacc gtaaggttct cccaggcgat gggctaatac gtccgcatga cggacaacac
     1141 taaaggcgct acttagaata ccaataagcg caagaagatt gatggcaatg accactggta
     1201 gtgtctggct gcttccccac aggaacagca ctaccagcgc cagaaccggg aaaataagcg
     1261 aagtctcctt gtggcgggtt tttaccgcct cttgagcatt tgacattatg gttatccctt
     1321 tgcagatgaa tttatcgaaa atgtaaaaaa taggtaggaa aaataacaga aagtgtctgg
     1381 atatcggtaa cattttacga atttttaccc cactgtcgat tttttactca ttgggacata
     1441 aaaataagta ttacgtttag acaatgtttg ttttagcgtt tcttaagaac agtctgacat
     1501 gaaaattctt atgttttggc aagagtagat attgttgacc acacttaatg ttcaactttg
     1561 taaaaggagt caacgatgcc gtataaaacg aaaagcgatc tgccggaaag cgtaaagcac
     1621 gttctaccgt ctcatgccca ggatatctat aaagaagcgt tcaacagcgc atgggatcaa
     1681 tataaagata aagacgatcg gcgtgatgac gccagtcgcg aagaaaccgc gcataaagtg
     1741 gcctgggctg ctgtgaagca tgaatatgcc aaaggggatg atgataaatg gcataaaaaa
     1801 tcgtaaaacc ggtagcttag ttaaagctat tcgtgcggtg ttgccttgca agtggtccgt
     1861 ggattgcata ttgtcccgtt agtggtttca aaatgagcag taaaaatgtc cggaagacac
     1921 caaaaagttg tcgcagggaa gtatgcagtg gcggaggtgt aaggtgataa cgcgtgattt
     1981 cttgatgaat gccgattgta aaacggcatt tggtgccatt gaagaatcac tcttatggtc
     2041 agcagagcaa cgggcggctt cgctggcggc gacgctggct tgtcgacctg atgagggacc
     2101 ggtgtggatc ttcggttatg gatcgttgat gtggaatccg gcactggagt ttaccgagtc
     2161 gtgcaccggt acactggttg gatggcatcg cgcgttttgc ctgcgcctga ccgccgggcg
     2221 cgggactgcg caccagccgg gacggatgct tgcactgaaa gagggcggac gcactacagg
     2281 cgtcgcctat cgactgccag aagagacgct ggagcaggaa ctaaccctgt tgtggaagcg
     2341 cgagatgatt accggctgtt atctgccaac ctggtgtcag cttgatcttg atgatggatg
     2401 cacagtaaac gccattgtgt ttattatgga cccgcgacat ccagaatatg aatctgacac
     2461 tcgcgctcag gtcatcgcgc cgttgattgc ggcggcgagc ggtccgctgg gaaccaacgc
     2521 acaatacctg ttttcactgg aacaggagct tatcaaactg ggaatgcagg acgatgggct
     2581 gaatgatttg ctggtatcgg taaaaaaact gctggcggag aattatccgg atggtgtgtt
     2641 acggccggga ttcgcctgag taaacttccc tcatagtggg gcgtcagacg ccccctcaaa
     2701 cattaaaatg tgagcacttt atcggctgac agcgtccatt gcgccagttc cacaagagta
     2761 ccgatttcca ccccatcaat aagaggatgt gtgctaatcc cgcgcccgtc ggtacaggtt
     2821 ttgcacaatt tcaccggtac attctgagcg gtaaggatct ccagcatttg ctgaatgttg
     2881 tagccttccc ctggtttttg cccgcgcaac ccggctgtga ccgcatcaga catcaggaac
     2941 agacgcagat ccagattgct ctcctgctct cgtaacgcaa tggccagccg caagctgtta
     3001 aacaaggatt cgctcccgta aggtgcgcca ttggcaacga tcacgatttt ttgcattatt
     3061 tactcctgta ttcagggaat tagacattca tcttctatct tactgcttct gcagcgtctg
     3121 accaatcggt cacattttta aggattttcc tgaaagcgcg agaaaatacg acaaaagttg
     3181 ccagtaatcg ttattcttta aggctatggt ttttcattat taccggaagt taccgacgtt
     3241 ttgagccgtt tcgttcctcg cattatcccg ttttatttac tcttgcttgt agcaggcggt
     3301 acagctaacg cacaatctac cttcgagcaa aaagcggcaa atccctttga taataacaat
     3361 gatggtctgc cggatttagg catggctccc gaaaatcatg atggggaaaa acactttgct
     3421 gaaattgtga aagatttcgg cgaaaccagt atgaatgata acgggctgga tactggcgag
     3481 caggcaaaag ctttcgcatt gggaaaagtc cgcgacgcgc ttagtcaaca ggttaatcag
     3541 cacgtagagt cctggctatc accgtgggga aatgccagtg ttgacgtcaa agtggataac
     3601 gaaggacatt tcaccggcag tcgtggaagc tggtttgtgc cgttacaaga taatgatcgt
     3661 tatctcacct ggagccagct tggtcttact cagcaggatg atgggttggt gagcaatgtg
     3721 ggcgttgggc aacgctgggc gcgcggcaac tggctggtgg gttataacac tttttatgac
     3781 aacttgctgg acgaaaatct tcagcgagcg ggctttggtg ccgaagcgtg gggcgaatat
     3841 ttgcgactat cggcaaactt ttatcagccg tttgctgcat ggcatgaaca gacagccacg
     3901 caggaacaac ggatggcgcg cgggtatgac ctgacagccc ggatgcgcat gccgttctat
     3961 caacacctca ataccagtgt cagcgtagaa cagtattttg gtgatcgtgt tgatttgttt
     4021 aactctggta cgggttatca caatcccgtc gcgttgagtc tgggattaaa ttacacccct
     4081 gtgccattag tcactgtgac ggcccagcat aaacagggtg aaagtggcga gaatcaaaat
     4141 aacctcgggc tgaatcttaa ttaccgcttt ggtgtaccgc tcaaaaaaca actttctgcg
     4201 ggcgaggttg ccgaaagtca gtcgttacgt ggtagtcgct atgacaatcc gcagcgaaat
     4261 aatctaccga ctcttgagta ccgacagcga aaaacgttaa cggtgtttct ggcgacaccg
     4321 ccgtgggatc taaaacctgg cgaaacagtg ccgctgaaat tacaaatccg cagtcgttac
     4381 ggtattcggc aactgatttg gcagggcgat acgcagatat taagtttgac gccgggcgca
     4441 caagccaaca gcgcggaggg ctggacgctg atcatgcctg actggcagaa cggggaaggg
     4501 gcaagcaatc actggcgatt atcggtggtg gtggaagata accaggggca gcgtgtctcc
     4561 tccaatgaga tcacgctaac gcttgtcgaa ccgttcgatg cattgtcaaa cgacgaactg
     4621 cgctgggaac cgtaatcaga aaatgcgctc ctgatgcacc cataccgctg cttccacgcg
     4681 agacttgagc ttcattttct tcagcatgtg cttgacgtgc acttttactg tgctttcggt
     4741 gatatccagg cggcgggcaa tcatcttgtt cggcaaaccc tgggcaatca gcttgagaat
     4801 atcgcgctcg cgtggggtta actggttaac atcgcgctca gtagtggcac ggttagcgcg
     4861 caagctggcg gccagaacag gcgttaatgc ttcgcttaat accatttcgc cagcagctgc
     4921 ctgatgcaat gctttcagca gatcttccgg ttccatatct tttaacagat agccatccgc
     4981 gccgcgtttc agtgcggtga ccacatcttc ttcatggtta gagacgctga ataccacaat
     5041 gcgccctgag agggactttt cgcgcagttt atccagcgtt tccagaccgt tcatgccggg
     5101 catattgaga tctaacagga tcagatcggg atcaagagac tccgccagtt caataccctg
     5161 ttcgccatta ctcgcttcgc caaccacggt gatatctggt gccatactga taagctgttt
     5221 tacgccagtt cgcagcatcg ggtgatcgtc aatcagcagg atagtagccg gttcctgatt
     5281 actcatgggt atctccttgg acgtctgtga aagttttttc gggaataaag gtgaccacca
     5341 cttcggtgcc acctgattca cgacggcgga cgcggcaatc gcctcgtaaa ctttgcgcac
     5401 ggtcgcgcat tattatcatg ccgtagtgat tgctgcggat ggcattttca ggcacgccgc
     5461 agccattatc ctgaacggtc agttttacct gattatcgtt ttgcgccacc gtcaccacga
     5521 cctcactcgc ttgcgaatgt ttgagggcgt tacttaatgc ctcacgggca atttgcaaca
     5581 agtggattgc ctgatgcgaa ggcaccagac gaggcggcaa ttgataatcc agcttcaccg
     5641 ggaagccaaa tttggcgctg tactcttcgc aactcgcctc cagcgccgga cgtaatccag
     5701 gctcggtgag ctgcaagcgg aatgtggtga gcaattcacg caactgcgcc caggatgcat
     5761 tcagttcgtt acggatctga cttaacagtt cgcggctgct ttctggcagc gcatcgccct
     5821 gcatctgtaa acaactcacc tgcatcttca tgcaagagag agattgggca atagaatcat
     5881 gcagttcgcg cgcaatggtg gcacgctctt ccatcacgat caactgttgc tgacgttcct
     5941 gatggcgatc cagcgccagc gtggcggtga gttgttcaac cagggtatcc accagttgtt
     6001 gttgatcatg gctaagatga cgcccctgcg gcagggtcgc cagcaaaata ccgtactgcg
     6061 tatgagagtc agccagccgc cacttcaggg tcgtgccgcg atcgccaacg ggtaatacgc
     6121 cgcgcgggca gagctggcag cctttatcat cacaagtcat atctggctgg caggtaaact
     6181 cctgatgatt ctcttcatcg tcagtatcat aaacccgcag ttcgatatca cgtagcaggg
     6241 ttaaattctg taagccgttg agtacaggtg acaggcgttc acacagcggg gcgcgggaat
     6301 gcaaacggcg gttagcctgc cataaaaaag agaggatctg atttttatgc tccagcccgg
     6361 cggttttctc ctgaacccgc tgctcaagta cggcataact ttcggccagt tctgcagaca
     6421 tattgttcaa tgcagttcca agcatcgcca tttcgttgcg cccgctgatg ttcgcgcgtt
     6481 gggtaaaatc gcgatggctg acggcactcg ccattgccag cagttgccgc cacggttgta
     6541 gcagtcgcgc ccgcaaccaa ataatagtga acaccagtaa aagtgccata aataccgcca
     6601 ttacccgatg gaccagtacc actgtctcaa tgcgcatttc cgtggtgcgg tcaaaaccag
     6661 ataccagctg atcaagcccg gcaacaaact ggctgacatc cgctgacacc gtttcgcggt
     6721 tttgtgcacg tatcagcgca gggatcagtt cattacgcca gtaatcttgt aaaccctgta
     6781 attgcgccag ttgtccgtct cgttctgctg ctcgagtcaa ctcggcgcta aatgccgttt
     6841 gttccatctc tttaattaag ggcttgtctt tctcgcttaa tggcactgct gccaacagac
     6901 ggtaactttg catgcgcagc gatcccgctt tgttgatcgc atgggcgctg ccctgaacgc
     6961 cttgcaccag ccagccagaa accgccatcc ctgccagtcc aatagcagta gaaagcaaca
     7021 caataagcgc aacctgatta accagggtga gcggagagag acaacgtttg agcatgtaaa
     7081 cctcttcctt caggctttaa atgagcaata accttaatga atgtgacgat acattctgga
     7141 atggcagtat tctcggctat tggctgaagt atacccatac ccggaaggag ttactcctta
     7201 tttgccgtgt ggttagtcgc tttacatcgg taagggtagg gattttacag caccgtgaaa
     7261 aatctcataa tttttatgaa atcactgtac tcactatggg taatgataaa tatcaatgat
     7321 agataaagtt atcttatcgt ttgatttaca tcaaattgcc tttagctaca gacactaagg
     7381 tggcagacat cgaaacgagt atcagaggtg tctatgagtc actcatccgc ccccgaaagg
     7441 gctactggag ctgtcattac agattggcga ccggaagatc ctgcgttctg gcaacaacgc
     7501 ggtcaacgta ttgccagccg caacctgtgg atttccgttc cctgtctgct gctggcgttt
     7561 tgtgtatgga tgttgttcag cgctgttgcg gtgaacttac cgaaagtcgg ttttaatttt
     7621 acgaccgatc agctatttat gttgactgcg ctgccttcag tttctggcgc gttattacgt
     7681 gttccatact cctttatggt tcctatcttc ggtggtcgtc gctggacggc gttcagcacc
     7741 ggtattctga ttattccttg tgtctggctg ggttttgccg tgcaggatac ctccacgcct
     7801 tatagcgtct tcatcatcat ctctctgctg tgcggctttg ctggcgcgaa cttcgcctcc
     7861 agtatggcaa acatcagctt cttctttccg aaacagaagc agggtggcgc gctgggtctg
     7921 aatggtggtc tgggcaacat gggcgtcagc gtcatgcagt tggttgctcc gctggtggta
     7981 tcactgtcga ttttcgcagt atttggtagc cagggcgtca aacagccgga tgggactgag
     8041 ctgtatctgg cgaatgcgtc ctggatatgg gtgccgttcc ttgccatctt caccattgcg
     8101 gcgtggtttg gcatgaacga tcttgctacc tcgaaagcct ccatcaagga gcagttgccg
     8161 gtactcaaac gggggcatct gtggattatg agcctgctgt atctggcaac cttcggctcc
     8221 tttatcggct tctccgcggg ctttgcgatg ctgtcaaaaa cgcagttccc ggatgttcag
     8281 attctgcaat acgctttctt cgggccgttt attggtgcgc tggcgcgttc tgcaggtggt
     8341 gcattatctg accgtctggg cggaactcgt gtcacgctgg tgaactttat tctgatggcg
     8401 attttcagcg gcctgctgtt cctgacctta ccgactgacg ggcagggcgg aagctttatg
     8461 gcgttcttcg cggtcttcct ggcgctgttc ctgacagctg ggctgggtag tggttccact
     8521 ttccagatga tttcagtgat cttccgtaaa ctgacaatgg atcgcgtgaa agcagaaggg
     8581 ggttctgacg aacgtgcgat gcgtgaagcg gcaaccgaca cggcggcggc gttgggtttc
     8641 atctctgcga ttggcgcgat tggtggcttc tttatcccga aagcgtttgg tagctcgctg
     8701 gcattaacgg gttcgccagt cggcgcaatg aaagtatttt tgattttcta tatcgcctgc
     8761 gtagtgatta cctgggcggt atatggtcgg cattctaaaa aataaaccgt tactcgtcat
     8821 acttcgggtt acatgtgctg cggctgcgtt cattcacccc agtcacttac tttagtaagc
     8881 tcctgggatt cattcacttg ccgccttcct gtaaaccgaa ttatatagag taaaatattt
     8941 gattatcctt tgcgcggcat gatgtcgcgc tttttttatg cgtcatttag ttacaacata
     9001 ctaatgttgt atggtttatt tcgccggatt tcattaagag ccattaatat gttacccatg
     9061 gggaatactc cttaataccc atctgcataa aattcttaat agtttaaata actacaggtg
     9121 taaaacgtct taatttacag catgttatgc tttaactgtt aattatccta aaggggtatc
     9181 ttaggaattt actttatttt tcatccccat cacacttgat cgttatcaat tcccacgctg
     9241 tttcagagcg ttaccttgcc cttaaacatt agcaatgtcg atttatcaga gggccgacag
     9301 gctcccacag gagaaaaccg atgagtaaat tcctggaccg gtttcgctac ttcaaacaga
     9361 agggtgaaac ctttgccgat gggcatggcc agcttctcaa taccaaccgt gactgggagg
     9421 atggatatcg ccagcgttgg cagcatgaca aaatcgtccg ctctacccac ggggtaaact
     9481 gcaccggctc ctgcagctgg aaaatctacg tcaaaaacgg tctggtcacc tgggaaaccc
     9541 agcagactga ctatccacgt actcgcccgg acctgccaaa ccatgaacct cgcggctgcc
     9601 cgcgcggtgc cagctactcc tggtatcttt acagcgccaa ccgcctgaaa tacccgatga
     9661 tgcgcaaacg cttgatgaaa atgtggcgtg aagcgaaggc gctgcatagc gatccggttg
     9721 aggcatgggc ttctatcatt gaagacgccg ataaagcgaa aagctttaag caggcgcgtg
     9781 gacgcggtgg ttttgttcgt tcttcctggc aggaagtgaa cgaactgatc gccgcatcta
     9841 acgtttacac catcaaaaac tacggcccgg accgtgtcgc tggcttctcg ccaattccgg
     9901 caatgtcgat ggtttcttac gcatcgggtg cacgctatct ctcgctgatt ggcggtactt
     9961 gcttaagctt ctacgactgg tactgcgacc tgcctcctgc gtctccgcaa acctggggcg
    10021 agcaaacaga cgtaccggaa tctgctgact ggtacaactc cagctacatc atcgcctggg
    10081 ggtcaaacgt gccgcagacg cgtaccccgg atgctcactt ctttactgaa gtgcgttaca
    10141 aagggaccaa aactgttgcc gtcacgccgg actacgctga aatcgccaaa ctgtgcgatc
    10201 tgtggctggc accgaaacag ggcaccgatg cggcaatggc gctggcaatg ggccacgtaa
    10261 tgctgcgtga attccacctc gacaacccaa gccagtattt caccgactat gtgcgtcgct
    10321 acaccgacat gccgatgctg gtgatgctgg aagagcgcga cggttactac gccgcgggtc
    10381 gtatgctgcg cgctgctgat ctggtggatg cgctgggtca ggaaaacaat ccggaatgga
    10441 aaactgtcgc ctttaatacc aatggtgaaa tggttgcgcc gaacggttct attggcttcc
    10501 gctggggcga gaagggcaaa tggaatcttg agcagcgcga cggcaaaact ggcgaagaaa
    10561 ccgagctgca actgagcctg ctgggtagcc aggatgagat cgctgaggtg ggcttcccgt
    10621 actttggtgg cgacggtact gaacacttca acaaagtgga actggaaaac gtgctgctgc
    10681 acaaactgcc ggtgaaacgc ctgcaactgg ctgatggcag caccgccctg gtgaccaccg
    10741 tttatgatct gacgctggca aactacggtc tggaacgtgg cctgaacgac gttaactgtg
    10801 caaccagcta tgacgatgtg aaagcttata ccccggcctg ggccgagcag attaccggcg
    10861 tttctcgcag ccagattatt cgcatcgccc gtgaatttgc cgataacgct gataaaacgc
    10921 acggtcgttc gatgattatc gtcggtgcgg ggctgaacca ctggtatcac ctcgatatga
    10981 actatcgtgg tctgatcaac atgctgattt tctgcggctg tgtcggtcag agcgggggcg
    11041 gctgggcgca ctatgtaggt caggaaaaac tgcgtccgca aaccggctgg cagccgctgg
    11101 cgtttgccct tgactggcag cgtccggcgc gtcacatgaa cagcacttct tatttctata
    11161 accactccag ccagtggcgt tatgaaaccg tgactgcgga agaactgctg tcgccgatgg
    11221 cggataaatc ccgttatacc ggacacctaa tcgactttaa cgtccgtgca gaacgcatgg
    11281 gctggctgcc gtctgcaccg cagttaggca ctaacccgct gactatcgct ggcgaagcgg
    11341 aaaaagccgg gatgaatccg gtagattaca ccgtgaaatc cctgaaagag ggttccatcc
    11401 gttttgcggc agaacaacca gaaaacggta aaaaccaccc gcgcaacctg ttcatctggc
    11461 gttctaacct gctcggttct tccggtaaag gtcatgagtt tatgctcaag tacctgctgg
    11521 ggacggagca cggtatccag ggtaaagatc tggggcagca gggcggcgtg aagccggaag
    11581 aagtggactg gcaggacaat ggtctggaag gcaagctgga tctggtggtt acgctggact
    11641 tccgtctgtc gagcacctgt ctctattccg acatcatttt gccgacggcg acctggtacg
    11701 aaaaagacga catgaatact tcggatatgc atccgtttat tcacccgctg tctgcggcgg
    11761 tcgatccggc ctgggaagcg aaaagcgact gggaaatcta caaagccatc gcgaagaaat
    11821 tctccgaagt gtgcgtcggc catctgggta aagaaaccga catcgtcacg ctgcctatcc
    11881 agcacgactc tgccgctgaa ctggcgcagc cgctggatgt gaaagactgg aaaaaaggcg
    11941 aatgcgacct gatcccaggt aaaaccgcgc cacacattat ggtcgtagag cgcgattatc
    12001 cggcaactta cgaacgcttt acctctatcg gcccgctgat ggagaaaatc ggtaacggtg
    12061 gtaagggtat tgcctggaac acccagagcg agatggatct gctgcgtaag ctcaactaca
    12121 ccaaagcgga aggtccggca aaaggccagc cgatgctgaa caccgcaatt gatgcggcag
    12181 agatgatcct gacgctggca ccggaaacca acggtcaggt agccgtgaaa gcctgggctg
    12241 ccctgagcga gtttaccggt cgtgaccata cgcatctggc gctgaataaa gaagacgaga
    12301 agattcgctt ccgcgatatt caggcacagc cgcgcaaaat catctccagc ccgacctggt
    12361 ctggtctgga agatgaacac gtttcttaca acgccggtta caccaacgtt cacgagctga
    12421 tcccgtggcg tacgctctct ggtcgtcagc aactgtatca ggatcaccag tggatgcgtg
    12481 atttcggtga aagcctgctg gtttatcgtc cgccgatcga cacccgttcg gtgaaagaag
    12541 tgatgggcca gaaatccaat ggcaacccgg aaaaagcgct caacttcctg acgccgcacc
    12601 agaagtgggg tatccactcc acctacagcg acaacctgct gatgctgact ttaggtcgcg
    12661 gtggtccggt ggtctggttg agtgaagccg atgccaaaga tctgggtatc gccgataacg
    12721 actggattga agtattcaac agcaacggtg ctctgactgc ccgtgcggtt gtcagccagc
    12781 gtgttccggc agggatgacc atgatgtacc acgcgcagga acgtatcgtt aacctgcctg
    12841 gttcggaaat tacccaacag cgtggtggta tccataactc ggtcacccgt atcacgccga
    12901 aaccgacgca tatgatcggc ggctatgccc atctggcata cggctttaac tactatggca
    12961 ccgtaggttc taaccgcgat gagtttgttg tagtgcgtaa gatgaagaac attgactggt
    13021 tagatggcga aggcaatgac caggtacagg agagcgtaaa atgaaaattc gttcacaagt
    13081 cggcatggtg ctgaatctcg ataagtgcat cggctgccac acctgttcag ttacctgtaa
    13141 aaacgtctgg accagccgtg aaggcgtgga atacgcgtgg ttcaacaacg tggaaaccaa
    13201 gccgggccag ggcttcccga ctgactggga aaaccaggaa aaatacaaag gcggctggat
    13261 ccgtaaaatc aatggcaaac tgcagccgcg catgggtaac cgcgccatgc tgctgggtaa
    13321 aatcttcgct aacccgcatc tgccggggat cgacgattat tacgagccgt tcgattttga
    13381 ctatcagaac ctgcataccg cgccggaagg cagcaaagcg cagccgattg cccgtccgcg
    13441 ttcgctgatt accggggaac ggatggcgaa aatcgaaaaa gggccgaact gggaagatga
    13501 cctgggcggt gagtttgaca aactggcgaa agacaagaac ttcgacaaca tccagaaggc
    13561 gatgtatagc cagttcgaaa acacctttat gatgtatttg ccgcgcctgt gcgaacactg
    13621 cctgaacccg gcatgtgtgg cgacctgccc gagcggtgcg atttacaagc gtgaagaaga
    13681 tggcatcgtc ctgatcgacc aggataaatg ccgtggctgg cgtatgtgca tcaccggatg
    13741 cccgtacaaa aaaatctact tcaactggaa gagcggtaag tctgagaagt gcatcttctg
    13801 ctatccgcgt attgaagcgg gtcagccgac cgtgtgctca gaaacctgtg tcggtcgtat
    13861 ccgttatctt ggcgtgctgc tgtacgatgc cgacgcgatt gaacgtgcag ccagcaccga
    13921 gaacgagaaa gatctctacc agcgtcagct ggacgtgttc ctcgatccga acgatccgaa
    13981 agtcatcgag caggcgatta aagacggtat tccgctgagc gttattgaag ctgcacagca
    14041 gtcgccggtt tataaaatgg cgatggaatg gaaactggcg ctgccgctgc atccagaata
    14101 tcgcacactg ccgatggtct ggtacgtgcc gcctctgtct ccgattcagt ctgcagcaga
    14161 cgcgggcgag ctgggcagca acggaattct gccagacgtc gaaagcttgc gtattccggt
    14221 acagtatctg gcgaatctgc tgaccgccgg tgataccaaa ccggtactgc gcgcactgaa
    14281 acgtatgctg gcgatgcgtc attacaaacg tgctgaaacc gttgacggta aagttgatac
    14341 ccgtgcgctg gaagaggtcg gcctgactga agcccaggca caggagatgt accgttatct
    14401 ggcgattgct aactacgaag atcgctttgt ggtgccgagt agtcatcgtg aactggcacg
    14461 ggaagccttc ccggagaaaa atggctgcgg ctttaccttt ggtgatggct gccacggctc
    14521 agataccaaa ttcaatctgt tcaacagccg tcgtatcgat gccatcgatg tgaccagcaa
    14581 aacggagccg catccatgat cgaactcgtg attgtatcgc gtctccttga atatccggat
    14641 gctgccttat ggcagcatca acaggagatg tttgaggcga ttgccgcgtc ggaaaatttg
    14701 tcgaaagaag atgcccatgc gctgggcatt ttcctgcgcg atttaacggc gctggatccg
    14761 ctggatgccc aggcgcagta cagcgaactg ttcgaccgtg gtcgcgccac gtcgctgttg
    14821 ctgtttgaac atgtgcacgg cgaatcccgc gaccgcggcc aggcgatggt tgacctgttg
    14881 gcgcagtacg agcagcacgg cttgcagtta aacagccgcg aattgccgga ccatctgccg
    14941 ctgtatctgg agtacctggc tcagctgccg caaagcgaag ccgtggaagg tttgaaagat
    15001 atcgcgccga ttctggcatt gctgagcgcg cgtctgcaac agcgtgaaag ccgttatgcc
    15061 gtgctgtttg atctgctgct gaaattggcc aataccgcta tcgacagcga caaagtggcg
    15121 gaaaaaattg ccgacgaagc gcgcgatgat acgccgcagg cgctggatgc tgtctgggaa
    15181 gaagagcagg ttaaattctt tgctgacaaa ggctgcggtg attcagcaat cactgctcat
    15241 cagcgtcgct ttgccggtgc cgtcgcgccg caatatctga atatcaccac cggaggacag
    15301 cactaatgca attcctgaat atgttcttct ttgatatcta cccgtacata gccggggcgg
    15361 tcttcctgat tggtagctgg ctgcgttatg actacgggca gtacacctgg cgcgcggcgt
    15421 ccagccagat gctggatcgc aaagggatga acctggcgtc gaacctgttc catatcggta
    15481 ttctggggat ttttgtcggt cacttcttcg gtatgttgac gccgcactgg atgtatgaag
    15541 cctggctgcc gattgaagtg aaacagaaaa tggccatgtt tgctggtggt gccagcggcg
    15601 tgctgtgtct gattggcggc gtgctgttgc tgaagcgtcg tctgttcagc ccacgcgtgc
    15661 gtgcaaccac tactggagcg gatatcctga tcctgtcgct gctcgttatc cagtgcgcgc
    15721 tgggcctgct gaccattccg ttctccgctc agcatatgga cggtagcgag atgatgaaac
    15781 tggttggctg ggcgcagtcg gtggtgacct tccacggtgg cgcttctcaa cacctcgatg
    15841 gtgtggcgtt tatcttccgt ctgcacctgg tgctggggat gacgttattc ctgctgttcc
    15901 cgttctcgcg tctggtacac atctggagcg taccggtgga gtatctgaca cgtaagtacc
    15961 agctggtgcg cgctcgtcac taagcgaatt ttagttcaca tagaccctgc ttcggcgggg
    16021 tttttttatg ggcacggtgc ggggtgagtt gtcggatgcg cttcgcttat ccgacctaca
    16081 ggggaggata ttgtaggccc ggtaaacgtg gtgccatcgg gcaaaattag ctcggagtaa
    16141 caggttttga ttatttaagg aagcgatggt ggtgggggaa ggattactca gcgctgcgcg
    16201 cttcgccctt cgggtcgttg cctgcggcaa cgctctctcg ctggtgctca agtcgaacct
    16261 tggtcgaagc ttctcatcct tccccgcttg ggcagaatat ttaattgcgg attcgtttga
    16321 gagttcacgg acttttgaaa gtgatggtgg tgggggaagg attactcagc gctgcgcgct
    16381 tcgcccttcg ggtcgttgcc tgcggcaacg ctctctcgct ggcgctcaag tcgaaccttg
    16441 gtcgaagctt ctcatccttc cccgcttggg cagaatattt aattgcggat tcgtttgaga
    16501 gtttacggac ttttgaaaag tgatggtggt gggggaagga ttcgaacctt cgaagtcgat
    16561 gacggcagat ttacagtctg ctccctttgg ccgctcggga accccaccac ggggtaatgc
    16621 tttttactgg cctgctccct tatcgggaag cggggcgcat catatcaaat gacgcgccgc
    16681 tgtaaagtgt tacgttgaga aaaatgaact ggttgcgtaa ttttcatccg taacggatta
    16741 aaggtaacca gttatttttg ctggcgatta aagaataatc gtccgattac cgtaaacaaa
    16801 gacgcgctgt gccagtactt tgtatagcgc acgacttaag acgtttttct cgacgtcacg
    16861 acctgcgcgc atcatatctt cagctgtgta ggtatgatcg acatgaataa cgtcctgcat
    16921 gatgattggg ccttcgtcca gattgtcatt cacatagtga gcggttgcgc caataatctt
    16981 cacaccacgt tcataggcct ggtgataagg acgtgcgccg ataaacgcag gcaggaatga
    17041 atggtgaata ttgatgattt tattcgggaa gcgtgccaca aattccggcg ttaatacccg
    17101 catatacttc gccagcacca catagtcagg ttgataagca tcaatggcgt ccgccatctt
    17161 ttgatcgtgc tcgttgcggc ttaacccttc atggcttacc agctcaaacg gaatatcaaa
    17221 acgctcaacc agagaacgta aagtatcgtg gttaccaata actgccgcga tttcgacatc
    17281 caggccgccg taattggctt tcatcaacaa atcgccaagg caatgcgctt ctttagtgac
    17341 cagaatcact atccggcgac gaccggcagg attcagctca cgcacggagc cttctggcaa
    17401 tgcgctatcg agatccgcca gcagggtgga atcattaaaa atcccttcca gttccgtgcg
    17461 cataaaaaag cgcccggtac ggtgatcaac aaattcattg ttctgtacga tatttaactc
    17521 gtgcttgtag caaatattgg taatacgtgc gatcagacct ttttggtccg gacaaatagt
    17581 acgcagaact ttacgttgga gtgaatgcat tgctggaaaa accttgttga gagtgtttgc
    17641 taaaccgtac cgtcaaccat tattggccgc agcacttttt aaatttttta cctgaaccac
    17701 aagggcaggg atcgttgcga ccaaactgcg gacgtgtacc gtcaatatag taccattgac
    17761 cgttttcttt caaaaatcgc gaacgttcaa ttattgcacc tgttttacca ccttcggtaa
    17821 atcgagcaac aaaactgaca aatccgatat tgtcggcgtc ctgccaacaa tgttcaaata
    17881 cggtcaatcc caaccattca gtatgcgcaa atccggccat caattcggca cgtaacgccg
    17941 ctgctccaca agagggatgc caggtcttta ttaaataatc tgcgtcttgc atcacaaaag
    18001 cgcagtaacg cgaacgcatg agatgttctg gatcaggtgc aaccttttca ccagacacat
    18061 aagggtggca acataggcta tactcgacag cactaccaca gggacaaagc tgagacacaa
    18121 ataatctccc tggaaacaat aacggcgtat taaccgcctg agtagcacta tgttaaccga
    18181 gcagtagcga tgtggctacg attgcattcc aggggaatct tgcgggaata atgagaaaga
    18241 taaaaatagg gctggcgctg ggatctggcg cggcgagagg ttggtcgcat attggcgtta
    18301 ttaatgcgct aaaaaaagtg ggtattgaaa ttgatatcgt tgcaggatgt tcaattggtt
    18361 cgctggtggg cgctgcctat gcatgcgatc gattatctgc gctggaagat tgggtgacct
    18421 ctttcagtta ttgggatgtt ttacgcctga tggatctctc ctggcagcgc ggtgggttac
    18481 tgcgcggcga gcgtgtcttc aatcaatacc gcgaaataat gccggaaaca gagatcgaaa
    18541 attgttcccg tcgctttgcg gctgttgcca ccaatttaag tacgggacgt gaattatggt
    18601 ttactgaagg cgatctccat cttgctattc gcgcatcatg cagtattcca ggactcatgg
    18661 cacctgttgc acataacggc tactggctgg ttgatggagc agtcgttaac ccaattccta
    18721 tttccctcac gcgtgcattg ggggctgata ttgtgatagc ggttgacctg cagcacgatg
    18781 ctcatttgat gcaacaagat ttgctctcct ttaatgtcag tgaagaaaat agcgagaatg
    18841 gtgattctct gccgtggcat gcgcgtctga aagaaaggtt aggcagcata acgacacgtc
    18901 gggcggtgac agcgccaacg gcaacagaga ttatgaccac ttctatccag gtgctggaga
    18961 accgccttaa aaggaaccgc atggcaggtg atccgcccga tattctgatt caacctgttt
    19021 gcccgcaaat atctacgctt gatttccatc gcgcgcacgc tgccattgcg gccggacagc
    19081 tggcagtgga aaggaaaatg gacgaacttt tgccgttggt acgcaccaac atttgaccag
    19141 aatttttatc tacacttaag ttaattctga caggcgcagg tggcaatagc atgccactat
    19201 tgagtaaagc cagtcagggg agagaacatg acgcagccat tggtcggaaa acagattctc
    19261 attgttgaag atgagcaggt atttcgctcg cttctggatt catggttttc ctcattggga
    19321 gcgacaacgg tactggcggc tgatggggtg gatgcccttg agttgctggg aggtttcact
    19381 ccagacctga tgatatgtga tatcgcgatg ccacgaatga acgggcttaa actgctggag
    19441 catatacgta acagaggcga ccagacccca gttctggtga tatctgccac tgaaaatatg
    19501 gcagatattg ccaaagcgtt acgtctgggc gttgaagatg ttttgctgaa accagttaaa
    19561 gatctgaatc gcttgcgcga gatggttttt gcctgtctct atcccagcat gtttaattcg
    19621 cgcgttgagg aagaggaaag gctttttcgc gactgggatg caatggttga taaccctgcc
    19681 gcagcggcga aattattaca ggaactacaa ccgccggttc agcaggtgat ttcccattgc
    19741 cgggttaatt atcgtcaatt ggttgccgcg gacaaacccg gcctggtgct tgatattgcc
    19801 gcactttcgg aaaacgatct ggcattttat tgccttgatg tcactcgagc tggacataat
    19861 ggcgtacttg ctgccttgtt attacgcgca ttgtttaacg gattattaca ggaacagctt
    19921 gcacaccaaa atcaacggtt gccagagttg ggcgcgttat tgaagcaggt aaaccattta
    19981 ctccgtcagg ccaatctgcc ggggcagttt ccgctattag ttggctatta tcatcgcgaa
    20041 ctgaaaaatc tcattctggt ttctgcgggt ctgaatgcga cgttaaatac cggcgaacac
    20101 caggtgcaaa tcagtaatgg tgttccgtta ggcactttag gtaacgctta tttgaatcaa
    20161 ttgagccagc gatgcgatgc ctggcaatgc caaatatggg gaaccggtgg tcgactgcgc
    20221 ttgatgttgt ctgcagaatg agcaaacgat aacgcgggct aaatttgcat tacctgctaa
    20281 tgtcggctgg tggtactatc gtcgccattc gtataagtaa ttgtcttaat tatgctaact
    20341 cgcctccttt tcagaactta gccccttcgg ggtgctgata tactgggatg cgatacagaa
    20401 atatgaacac gttcaaaaca cgaacagtcc aggagaattt aaatggctgc cattaatacg
    20461 aaagtcaaaa aagccgttat ccccgttgcg ggattaggaa ccaggatgtt gccggcgacg
    20521 aaagccatcc cgaaagagat gctgccactt gtcgataagc cattaattca atacgtcgtg
    20581 aatgaatgta ttgcggctgg cattactgaa attgtgctgg ttactcactc atctaaaaac
    20641 tctattgaaa accactttga taccagtttt gaactggaag caatgctgga aaaacgtgta
    20701 aaacgtcaac tgcttgatga agtgcagtct atttgtccgc cgcacgtaac tattatgcaa
    20761 gttcgtcagg ggctggcgaa aggcctggga cacgcggtat tgtgtgctca cccggtagtg
    20821 ggtgatgaac cggtagctgt tattttgcct gatgttattc tggatgaata tgaatccgat
    20881 ttgtcacagg ataacctggc agagatgatc cgccgctttg atgaaacggg tcatagccag
    20941 atcatggttg aaccggttgc tgatgtgacc gcatatggcg ttgtggattg caaaggcgtt
    21001 gaattagcgc cgggtgaaag cgtaccgatg gttggtgtgg tagaaaaacc gaaagcggat
    21061 gttgcgccgt ctaatctcgc tattgtgggt cgttacgtac ttagcgcgga tatttggccg
    21121 ttgctggcaa aaacccctcc gggagctggt gatgaaattc agctcaccga cgcaattgat
    21181 atgctgatcg aaaaagaaac ggtggaagcc tatcatatga aagggaagag ccatgactgc
    21241 ggtaataaat taggttacat gcaggccttc gttgaatacg gtattcgtca taacaccctt
    21301 ggcacggaat ttaaagcctg gcttgaagaa gagatgggca ttaagaagta acatccgtat
    21361 cggtgttatc cacgaaacgg cgttgagcaa tcgacgccgt ttttttatag cttattctta
    21421 ttaaattgtc ttaaaccgga caataaaaaa tcccgccgct ggcgggattt taagcaagtg
    21481 caatctacaa aagattattg cttgatcagg aaatcgtcga gggatttacc ttgctcatcc
    21541 attgcttttt tgattacagc tggagtacgg ccttggccag tccaggtttt agtttcgccg
    21601 ttttcgtcaa cgtagctata ttttgccgga cgctgagcac gtttagcttt ggtgccagat
    21661 ttaacggcag caaggctatt cagcagttcg ttcgggtcaa taccgtcagc gatcagcatt
    21721 tcgcgatatt gctgcagttt acgagtgcgc tcttcaactt cagcagcagc cgcgctttct
    21781 tcttcgcgac gttcgttaac aacaacttct aatttttcca gcatttcttc cagcgtttca
    21841 agtgtacatt ctcttgcctg cgcacgaaga gtacggatgt tgttcagaat tttaagtgct
    21901 tcgctcattg tagtaatctc aaacttatat tggggtggtt tgttgaggta ataatagagc
    21961 cttaaattca gttgtgcaat agccaggaat gtaaggaatt caaaattgtt ctttattttg
    22021 tgccgccaat aaatatcttt tcataaaatt agccagaaaa gacgcggcat atagccctat
    22081 ttacaccgat gatttcgcag cacgtgaggt taaaacttcc tgattcatgt cacattttat
    22141 ggggagatta tcgtaggctg acgacctttc agtcttctgt attagttgtg tttacgagaa
    22201 ttccctatta agcgaatgat gaaaagtaga acagtcgcaa taagagcatg gacttagtat
    22261 tgcactatct cctggaggtc aacagagggc tattacttgc gcaacaggtt aaagattgtg
    22321 aatagttacc agcagtcatt tacccgctta taacaagcga ggcagttgta atgatagctc
    22381 agaaggatta tgcaaggctt cgtaagggag aacgcatata cccacttctg tgcatactgt
    22441 tgagctgaaa aactgacgaa ttatgataaa ctccagccaa ctttatttca tatcattgag
    22501 ggcctgtggc tgatggcaca gctatatttc tactattccg caatgaatgc gggtaagtct
    22561 acagcattgt tgcaatcttc atacaattac caggaacgcg gcatgcgcac tgtcgtatat
    22621 acggcagaaa ttgatgatcg ctttggtgcc gggaaagtca gttcgcgtat aggtttgtca
    22681 tcgcctgcaa aattatttaa ccaaaattca tcattatttg atgagattcg tgcggaacat
    22741 gaacagcagg caattcattg cgtactggtt gatgaatgcc agtttttaac cagacaacaa
    22801 gtatatgaat tatcggaggt tgtcgatcaa ctcgatatac ccgtactttg ttatggttta
    22861 cgtaccgatt ttcgaggtga attatttatt ggcagccaat acttactggc atggtccgac
    22921 aaactggttg aattaaaaac catctgtttt tgtggccgta aagcaagcat ggtgctgcgt
    22981 cttgatcaag caggcagacc ttataacgaa ggtgagcagg tggtaattgg tggtaatgaa
    23041 cgatacgttt ctgtatgccg taaacactat aaagaggcgt tacaagtcgg ctcattaacg
    23101 gctattcagg aaaggcatcg ccacgattaa taagaatttc tttactgaca gggtgagcag
    23161 ggcactttta tcctgtcagt tcgttttacg cacttcttcc gggctatata cccttctcgg
    23221 cagtttttta acgccgctat acgcctcaca gggctcttaa gcaccgacgt tgacttgtga
    23281 cctataaagt acaatatccc tgtgtttagg cgttatacat cgtcgcaaat atgatgaagg
    23341 ctaatgctgt cggtttatgg aaaagttgct ttgggtaaac aaaaaaacgg ccccagaagg
    23401 ggccgtttat attgccagac agcgctactg attaagcgga ttttttcgct tttttctcag
    23461 ctttagccgg agcggcttct tttttcgctg cagtttcacc ttctacataa tcacgaccgt
    23521 agtaggtatc cagcaggatc tgtttcagct cggagatcag cgggtaacgc gggttagcgc
    23581 cggtgcactg gtcatcgaac gcatcttcag acagtttatc cacgttcgcc aggaagtctg
    23641 cttcctgaac gccagcttca cggatagatt tcggaatacc cagttcagct ttcagcgttt
    23701 ccagccatgc cagcagtttc tcgatcttag cagcagtacg gtcgcccggt gcgctcagac
    23761 ccaagtggtc ggcaatttca gcataacgac ggcgagcctg cggacggtca tactggctga
    23821 atgcagtctg cttggtcggg ttgtcgttcg cattgtagcg aataacgtta caaatcagca
    23881 gggcgtttgc cagaccgtgc ggaatatgga actgggaacc cagtttgtgc gccattgagt
    23941 gacatacacc caggaaggcg ttcgcaaacg cgatacccgc gatagtcgct gcactgtgaa
    24001 cacgttcacg cgctaccgga tttttagacc cttcgtggta ggacgctggc agatattctt
    24061 tcagcagttt cagtgcctgc agagcctgac catcagagaa ctcagatgcc agtacagaaa
    24121 cataagcttc catggcgtga gttactgcgt ccagaccacc gaaagcacac agggacttcg
    24181 gcatgtccat aaccaggttg gcgtcgacaa tcgccatatc cggagtcagc gcatagtctg
    24241 ccagcggata tttctgacca gtagcgtcgt cagttacaac cgcaaacgga gtgacttcag
    24301 aacctgtacc agaagtggtg gtgacagcga tcattttcgc tttcacgccc attttcggga
    24361 acttgtagat acgtttacgg atatccataa agcgcagcgc cagctcttcg aagtgagttt
    24421 ccggatgttc gtacataacc cacatgatct tcgcggcgtc catcggggaa ccaccaccca
    24481 gcgcgataat cacgtctggt ttgaaggagt ttgccagttc tgcaccttta cgaacgatgc
    24541 tcagggtcgg gtccgcttct acttcgaaga agacttcagt ttcaacgcct gctgctttca
    24601 gtacggaagt gatctgatca gcataaccat tgttgaacag gaagcggtca gtcacgatga
    24661 gcgcacgttt gtggccatca gtaatcactt catccagcgc gattggcagg gagccacggc
    24721 ggaagtagat agatttcgga agtttgtgcc acaacatgtt ttcagctcgc ttagcaacgg
    24781 ttttcttgtt gatcaggtgt ttcggaccaa cgttttcaga gatggagtta ccaccccaag
    24841 aaccacaacc cagagtcagg gaaggtgcga gtttgaagtt atacaggtca ccgataccac
    24901 cctgagacgc tggggtgtta atcaggatac gagccgtttt cattttttga ccgaagtaag
    24961 aaacgcgagc cggttggtta tcctggtcag tgtacaggca agaggtatga ccgataccgc
    25021 ccatagcaac cagtttctct gctttttcta ccgcgtcttc gaaatcttta gcgcggtaca
    25081 ttgccagagt cggggacagt ttttcatgtg cgaacggttc gctttcatca acaacggtca
    25141 cttcaccgat cagaatcttg gtgttttctg gtacagagaa gcctgccagt tcagctattt
    25201 tataggctgg ctgaccaacg atagccgcgt tcagcgcacc gtttttcagg ataacatcct
    25261 gaacagcttt cagctcttta ccctgcaaca gatagccgcc gtgggttgca aaacgttcac
    25321 gtacagcgtc ataaacagag tcaacaacaa caacagactg ttcagaagca cagattacgc
    25381 cgttgtcgaa ggttttggac atcagtacag atgcaactgc acgtttgata tcagcagttt
    25441 catcgataac aactggagtg ttgcccgcgc ctacaccgat agctggttta ccggagctgt
    25501 atgcggcttt aaccatgccc ggaccaccag ttgcgaggat caggttgatg tctgggtggt
    25561 gcatcagtgc gttagacagt tcaacagaag gttgatcgat ccagccgatc agatctttcg
    25621 gagcaccggc agcgatagca gcctgcagaa cgatatcagc cgctttgttg gtggcatctt
    25681 ttgcacgcgg gtgcggggag aagataatgg cgttacgggt cttcagactg atcagcgatt
    25741 tgaagatagc agttgaagtc gggttagtgg tcggaacgat accgcaaata ataccgattg
    25801 gttcagcgat agtgatggta ccaaaagtgt cgtcttcaga cagaacacca caggtttttt
    25861 catctttata ggcgttgtag atatattcag aagcaaagtg gtttttgatc actttatctt
    25921 cgacgatacc catgccggat tcggcaacgg ccattttcgc gagtgggatt cgagcatctg
    25981 cagcagccag agcggcggcg cggaagattt tgtctacttg ctcttgagtg aaactggcat
    26041 attcacgctg ggcttttttt acacgctcta cgagtgcgtt aagttcagcg acattagtaa
    26101 cagccataat gctctcctga taatgttaaa cttttttagt aaatcatctg ctcgaatacg
    26161 agagtatagt cagtgcggtg atgatttgct taacctatga aaatcaaaag cttactcgcg
    26221 atcacactca ctgtgattta ctaaaagagt ttaaacatta gagttattat ctctaatgcg
    26281 tcacttccag gtggcgtaag caagattact cacttctggg tactgattac gtgatccaaa
    26341 tcaaattttt gcaaagctga cacctttcag catcgctttt cgccattata gctaacagtt
    26401 aataaattgt agtatgattt ggtggctaca ttagcatgtt ttgcacaact agataacaat
    26461 aacgaatgat agcaatttta agtagttagg aggtgaaaaa tgctgtcaaa aggcgtattg
    26521 tcagcgcgtc ttttcaacct tatttatggc taacattatc cggcttttgc ttcggagcta
    26581 accgtgattc agaccttttt tgattttccc gtttacttca aatttttcat cgggttattt
    26641 gcgctggtca acccggtagg gattattccc gtctttatca gcatgaccag ttatcagaca
    26701 gcggcagcgc gaaacaaaac taaccttaca gccaacctgt ctgtggccat tatcttgtgg
    26761 atctcgcttt ttctcggcga cacgattctg caactttttg gtatatcaat tgattcgttc
    26821 cgtatcgccg ggggcatcct ggtggtgacg atagcgatgt cgatgatcag cggcaagctt
    26881 ggcgaggata aacagaacaa gcaagaaaaa tcagaaaccg cggtacgtga aagcattggt
    26941 gtggtgccat tggcgttgcc gttgatggcg gggccagggg cgatcagttc taccatcgtc
    27001 tggggtacgc gttatcacag cattagctat ctgtttggtt tctttgtggc tattgcattg
    27061 ttcgctttat gttgctgggg attgttccgc atggcaccgt ggctggtacg ggttttacgc
    27121 cagaccggca tcaacgtgat tacgcgtatt atggggctat tgctgatggc attggggatt
    27181 gaatttatcg ttactggtat taaggggatt ttccccggcc tgcttaatta attcctttca
    27241 aatgaaacgg agctgccatg ctccgtttac ttcgtcatta tttttacttt gttcccgcgc
    27301 agttatcaaa agcaaaagga ataggtaaaa atattcttct caaattacag ttagttataa
    27361 ggatttcctt aactgcttct cctcaccatc atgttatttt cgccacatca taatcctggg
    27421 cttgctgaag aataattgaa atgatattag taattccact gcctttggta gaggaaagtg
    27481 ctaaataata atcaattgtt aaattattgt gcatttcact actggaactg taatcagaaa
    27541 agatagacat gcttagccaa tctctatttg attgaattga aagatgtttg ttaaggcatg
    27601 gatgcaagct atagattctg atacggtcaa taaaagagaa ttgcttaaca attttgcaaa
    27661 atgtattggc gagtaagaac cgcatttggt actttccggg caaccgccag acgattcttt
    27721 attggtaatg agaataatta acaattaaag agcgtcgcga aagaataatg tgtctcgaca
    27781 ggggagacac agtacgaatc gacataaggt gatcgtctga atcaccagaa taaataaagt
    27841 cggtgatagt aatacgtaac gataaagtaa cctgacagca gaaagtctcc gagcctgtgc
    27901 agggtcccaa tccgggatta cacatgctgg ttaataccag taattataat gagggagtcc
    27961 aaaaaacaat gaccaacatc accaagagaa gtttagtagc agctggcgtt ctggctgcgc
    28021 taatggcagg gaatgtcgcg ctggcagctg atgtacccgc aggcgtcaca ctggcggaaa
    28081 aacaaacact ggtacgtaac aatggttcag aagttcagtc attagatccg cacaaaattg
    28141 aaggtgttcc ggagtctaat atcagccgag acctgtttga aggcttactg gtcagcgatc
    28201 ttgacggtca tccagcacct ggcgtcgctg aatcctggga taataaagac gcgaaagtct
    28261 ggaccttcca tttgcgtaaa gatgcgaaat ggtctgatgg cacgccagtc acagcacaag
    28321 actttgtgta tagctggcaa cgttctgttg atccgaacac tgcttctccg tatgccagtt
    28381 atctgcaata tgggcatatc gccggtattg atgaaattct tgaagggaaa aaaccgatta
    28441 ccgatctcgg cgtgaaagct attgatgatc acacattaga agtcacctta agtgaacccg
    28501 ttccgtactt ctataaatta cttgttcacc catcaacttc accggtgcca aaagccgcta
    28561 tcgagaaatt cggcgaaaaa tggacccagc ctggtaatat cgtcaccaac ggtgcctata
    28621 ccttaaaaga ttgggtcgta aacgaacgaa tcgttcttga acgcagcccg acctactgga
    28681 acaacgcgaa aaccgttatt aaccaggtaa cctatttgcc tattgcttct gaagttaccg
    28741 atgtcaaccg ctaccgtagt ggtgaaatcg acatgactta taacaacatg ccgatcgaat
    28801 tgttccagaa gctgaaaaaa gagatcccgg acgaagttca cgttgatcca tacctgtgca
    28861 cttactatta cgaaattaac aaccagaaac cgccattcaa cgatgtgcgt gtgcgtaccg
    28921 cactgaaact aggtatggac cgcgatatca ttgttaataa agtgaaagcg cagggcgaca
    28981 tgcccgccta tggttacact ccaccgtata ctgatggcgc aaaattgact cagccggaat
    29041 ggtttggctg gagccaggaa aaacgtaacg aagaagcgaa aaaactgctg gctgaagcgg
    29101 gttataccgc agacaaaccg ttgaccatca acctgttgta taacacctcc gatctgcata
    29161 aaaagctggc gattgctgcc tcttcattgt ggaagaaaaa cattggtgta aacgtcaaac
    29221 tggttaacca ggagtggaaa acgttcctcg acacccgtca ccagggtact tttgatgtgg
    29281 cccgtgcagg ctggtgtgct gactacaacg aaccaacttc cttcctgaac accatgcttt
    29341 cgaacagctc gatgaatacc gcgcattata agagcccggc ctttgacagc attatggcgg
    29401 aaacgctgaa agtgactgac gaggcgcggc gcacagctct gtacactaaa gcagaacaac
    29461 agctggataa ggattcggcc attgttcctg tttattacta cgtgaatgcg cgtctggtga
    29521 aaccgtgggt tggtggctat accggcaaag atccgctgga taatacctat acccggaata
    29581 tgtacattgt gaagcactaa tggcaatacg tggggcagga gtgtcctgct ccacggtgtc
    29641 tgatttttat cgcattacag aaggcacagg ccagaaggta gggcaatgtt aaaatttatt
    29701 ctacgtcgct gtctggaagc gattccgacg ctatttattc ttataactat ttcgttcttt
    29761 atgatgcgcc tcgcgccggg aagccctttt accggcgaac gtactttacc gccagaagtg
    29821 atggccaata tcgaagcgaa atatcatctt aatgatccga tcatgacaca gtatttcagc
    29881 tacctgaaac aactggcgca cggtgatttc ggtccatcgt ttaaatataa agattattcg
    29941 gtcaatgact tggttgcatc cagttttccc gtttctgcca aactgggagc cgcagcattt
    30001 ttccttgcgg taatactggg tgttagtgct ggcgttattg ccgcattaaa acaaaacacc
    30061 aaatgggact ataccgtgat ggggctggca atgaccgggg ttgttatccc cagttttgtg
    30121 gttgcaccat tattagtcat gatatttgcg atcattttgc attggctgcc gggcggtggc
    30181 tggaatggtg gggcgcttaa attcatgata ttgccgatgg tggcgttgtc actcgcttat
    30241 atcgccagta ttgcgcgtat tacccgtggc tctatgattg aagtattaca ctccaatttt
    30301 attcgtactg cccgggcgaa agggttacct atgcggcgga tcattttacg tcacgcatta
    30361 aaacctgctc tgttacccgt gctctcttat atgggccccg catttgtcgg cattattacc
    30421 ggttctatgg ttatcgaaac catttatggt ttgccgggga ttggacaact gttcgttaat
    30481 ggcgcattga accgtgacta ttccttagtg ttaagcctga ccatcctggt tggtgcttta
    30541 accattttgt ttaatgccat tgtcgatgtg ctatatgcgg ttatcgaccc gaaaattcgt
    30601 tactgatact ggagctcgcg atgatgttaa gtaagaaaaa cagcgagacg ctggaaaatt
    30661 tcagtgaaaa gctggaggtc gaagggcgca gcttgtggca ggacgcacgt cgacgtttta
    30721 tgcataaccg tgcggcggtt gccagtctga tagtgctggt gctgatcgcg ttatttgtaa
    30781 tcctggcacc gatgctttcc cagtttgcct atgacgatac tgactgggcg atgatgtcca
    30841 gcgccccgga tatggagtcc ggtcactact ttggtactga ctcatccggt cgcgacctgc
    30901 ttgtgcgcgt tgcgattggc gggcgtatct cactcatggt cggtgttgct gcggcactgg
    30961 tggctgtggt cgtcgggaca ctttatggtt cgctttccgg ttatctgggc ggtaaagtgg
    31021 attcggtaat gatgcgtctg ctggaaatcc tcaactcctt cccattcatg ttcttcgtca
    31081 ttttgcttgt gacctttttc ggtcaaaaca tcctgctgat tttcgtggcg attggcatgg
    31141 tttcctggct ggatatggct cgtattgtgc gtgggcaaac cctgagtctg aagcgcaaag
    31201 agtttattga ggcggcacaa gttggcggtg tatcgacatc gggcattgtt attcgccaca
    31261 ttgtgccgaa tgtactcggt gtggtggtgg tctacgcatc acttctggtg cccagcatga
    31321 tcctctttga atctttcctt agcttcctgg ggttgggtac gcaagagccg ttaagcagct
    31381 ggggtgcatt gctgagtgat ggcgcgaact cgatggaagt ctctccatgg ttattgttgt
    31441 tcccagcggg attcctcgtg gtgacgctgt tttgtttcaa ctttatcggc gatggcttgc
    31501 gtgatgccct cgacccgaaa gatcgttaag gagtgcagcc atgagcgtaa ttgaaactgc
    31561 aactgtgccg ctcgcacaac aacaggctga cgcactgctg aacgtgaaag atttgcgtgt
    31621 cacctttagt accccggacg gcgacgtcac ggcggtcaat gatttgaatt tttccctacg
    31681 tgccggagaa acgctgggta ttgtaggtga gtctggttcg ggtaaatcgc aaactgcatt
    31741 tgcgttgatg ggcctgttgg ctgccaacgg acgtattggc ggatcggcaa ccttcaatgg
    31801 gcgtgaaatc ctcaatttgc cagagcatga actcaataaa ctgcgcgctg aacaaatctc
    31861 aatgattttt caggacccaa tgacttcgtt gaatccctat atgcgcgtcg gtgagcagtt
    31921 aatggaagtg ctgatgctgc ataagaacat gagcaaagct gaggcgtttg aagagtcggt
    31981 gcggatgctc gatgcggtaa aaatgccgga agcgcgtaaa cgcatgaaaa tgtacccgca
    32041 cgaattttct ggcggcatgc gtcagcgagt catgattgcg atggcattgc tatgtcgacc
    32101 taagctactg attgcggatg aacccactac tgcgctggac gtcaccgtac aggcgcagat
    32161 catgacgcta ttaaatgaac tgaagcggga atttaatacc gccatcatta tgatcaccca
    32221 cgatcttggc gtggtggcgg ggatctgcga caaagtgctg gtaatgtacg ccgggcgcac
    32281 gatggaatat ggcaatgcgc gcgatgtctt ttatcaaccc gttcatcctt attctatcgg
    32341 tttgctcaac gcggtgccgc gtcttgatgc ggaaggtgaa acaatgttga ccatcccggg
    32401 taatccgcca aacttgctgc gattaccgaa aggttgcccg ttccagccac gttgtccaca
    32461 tgcgatggaa atttgtagta gcgcaccgcc gctggaagag tttacgcctg gccgtctgcg
    32521 tgcttgcttt aaaccggtgg aggaactgtt atgaatgctg taactgaagg aagaaaagtc
    32581 ctccttgaaa tcgccgatct taaagtgcac tttgaaatca aagatggcaa acagtggttc
    32641 tggcaaccgc cgaaaacgct caaagccgtc gatggtgtca ctcttcgcct gtatgaaggg
    32701 gaaacattag gtgtggtagg ggaatcggga tgcggtaagt ccacctttgc tcgcgccatc
    32761 attggcttgg ttaaagcgac cgacggtcat gttgcctggt taggtaaaga gttgctgggc
    32821 atgaagcccg atgaatggcg tgccgttcgc agtgatattc agatgatttt ccaggatccg
    32881 ttggcatcgc taaacccgcg tatgaccatc ggcgagatca tcgctgaacc actgcgtact
    32941 tatcatccga aaatgtcacg ccaggaagtt cgcgagcgcg tgaaggcgat gatgctgaaa
    33001 gtcgggttat tgcctaacct gattaaccgc tatccgcatg agttctccgg tgggcagtgc
    33061 cagcgtatcg ggattgctcg tgctcttatt cttgaaccga agctgattat ctgcgatgag
    33121 ccggtttcgg cgctggacgt gtcaattcag gcgcaggtgg tcaacctgct ccagcagctg
    33181 caacgtgaga tgggattgtc attaattttt atcgctcatg acctggccgt ggtaaaacac
    33241 atttccgatc gtgtgttggt gatgtatctc ggccatgcgg tagaactggg gacctatgat
    33301 gaggtctacc acaatccact acatccttac accagggcat tgatgtcggc agtccccata
    33361 cctgatccgg atctggagaa gaacaaaacc atccagttac tggaagggga attaccgtcg
    33421 ccgatcaacc cgccttccgg ttgtgttttc cgtacccgtt gcccgattgc cggtccggag
    33481 tgcgccaaaa cacgtcctgt tctggagggg agtttcagac acgccgtttc ttgcctgaaa
    33541 gtcgatccgc tttaaacaca ataagggctg acagttgtca gccctttttc acgctaaaag
    33601 cgattattta ttcccgccag atgatatggc aaagtttgtg atctttttcg cggcataaca
    33661 gaatgcgggc gaaaacatcg ttgatttcac catcttcact gtccgccaga ccaatcacca
    33721 cttcggcaaa aaagtctggg ttcaaatcga aatcaacatg ttcctgccag tcttccgccg
    33781 gatcgaataa ctccgcgccg ccgcgctctt caaactgaag attgaacagc agaacatcag
    33841 ctggatcgag attgtcggca gccagttcga gaaaaatatc gtaggcctgc tcaagcgttt
    33901 catcttcagt caggcgattg tttagatcca tatccatagt cactacctgt ttaacctctg
    33961 ttggcgacgt tttacagcaa cggactgaag aagtaaaaca gtcgctcggc gacacgttgc
    34021 cataatggac gttttagcca taaacgggca tcgagcagac gtgaacgcga aatataatcg
    34081 tcctgaacgg cggcaaggtc tgcaccaaaa cctttatcgt cgattgccag ggtaatctcg
    34141 aaattcagcc acagactacg catatcaagg ttaacggtgc caaccagact tagttcgcca
    34201 tcgaccagca cgctcttggt atgcagtaac ccgccttcaa actgataaat tttaacccca
    34261 gcagcaagaa gttccgtaaa gaatgcgcga ctggcccagc cgaccagcat cgagtcattt
    34321 tttcgcggaa ggataatact gacatccacc ccgcgctgcg ccgccgtgca aatcgcatga
    34381 agtaaatcat cgcttggcac aaagtagggc gtggtcatga tcaaatattc acgcgccgaa
    34441 taagccgcag tcaataatgc ctggtgaatg agatcttccg gaaagccggg gccagaagca
    34501 attgtgtgaa tggtgtgacc gctggcctgt tcaaacggca taatattgac atctggtggt
    34561 ggcggcagaa tacgttttcc ggtttcaatc tcccagtcgc aggaataaat aatccccatc
    34621 gcggtggcga tggggccttc catacgcgcc atcagatcaa tccattgccc tacgcccgca
    34681 tcttgtttga agtagcgagg atcgaccata ttcatgctgc cggtgtacgc gatgtaatta
    34741 tcgatcatga tcatcttgcg atgttggcgc aggtccatac ggcgtaaaaa cacacgcatc
    34801 agattgacct ttaaggcttc gaccacttca ataccggcat tacgcattag ctcgggccac
    34861 gggctgcgga aaaaagccac actcccggcg gagtcgagca tcaatcggca atgaatacca
    34921 cgccgtgcag ccgccattaa tgattcagcc acctggtccg ccatgccgcc gggctgccag
    34981 atataaaaca ccatctcaat attatggcgc gcgagctgga tgtcgcggat taacgcctgc
    35041 atcacatcat ctgactcggt catcagttgt agctgattcc ctttgacccc agcgatcccc
    35101 tgacgacgct cgcaaagctt gaataatggc gcagcgacac tgctattttc ttcggcgaag
    35161 atatgcttac aggctttaag gtcgttaagc cattttgcgg tggaaggcca catcgctctg
    35221 gcgcgctcag cgcggcgttt gcctaaatgg agctcgccaa cggcaagata ggcaataatt
    35281 ccgactaacg gcagaatgta aataatcaac agccaggcca tcgcggaggg aactgcgcgt
    35341 cgtttcatta gaatgcgtaa agttacgcct gcaatgagca accagtatcc cagaatggcc
    35401 aaccaactca ccaacgtata aacggttgtc atagattaga aatccttttg aaagcgcatt
    35461 gttatgagtt tacgcatatg gattcatctg gcaaataaaa acgcgggaaa agcactggtc
    35521 agcgtcgggg gtgggggtat aatgaccatt ctgttattgc atagagtagt taacatgaag
    35581 cggagtagaa cggaagtggg gcgctggcgc atgcagcgtc aggctagccg acgtaaatcg
    35641 cgttggcttg aggggcaatc gcgccgaaat atgcgtatcc acagcatcag gaagtgcatt
    35701 ctaaacaaac agcgtaactc gttattgttt gcgatctaca atatctaaat gtactgggca
    35761 ccattgcggt gcccaataag tttactcttc cgtctttaaa ctctattttt gcgccgattc
    35821 tttactgtca gctttcgttt cttgttcatc gttatcgctg aaaataccat gacctgagtt
    35881 caacaacatt gaaacgagca tatcattatt aatctcttca ccatttaaaa ctcgcgccag
    35941 aatttcgctg ccaaacagtt gcggtgagag aatgatatcc ggatgtacca tcttaatctt
    36001 attcaggttt ttgctatcac tgacggcgag aactgttttg acatcactgc tcatatcttt
    36061 tgccgagagt acaacaaacg cgttatctgc atcgttatca ctcagcgcca gaatggcccg
    36121 gcaacgatcg attcccgctt tctttaatac tgaactgtca ttactgtcac cggggataac
    36181 atcagcgtta tcgcctaagc gttgctcaag ttgcttgata tcatcttcag gcaagttgct
    36241 gataaccgtt acgttttgtc cgcgttgatt cagttgcagg atcgtattga tggcgagaat
    36301 cgaatgtccg caaacaataa aatgatcttt acgatgcatt gtatgattgt ttccttttac
    36361 aagtttgttg aatcccccgc ggataagcgg accaaaaatt gaggtcatag atgtggcaaa
    36421 aacggtaatg ccggaaataa tgaccgaaat agtgaacaat cgtgctgatt cagaaacagg
    36481 gacaatatcg ccatagccga cggttgacat ggtttctatc gaaaaataga acgccgtcat
    36541 caaactttct attcgcggat taaaaccttc gcttaaataa agcgcaccgt aggttgagta
    36601 aaacagtaat gtcgtgaaac taataaatgc aaaaattgtc ccggctgcgg cgctactgtg
    36661 ggagaagtct ttgcgcagta tcagcaaaaa caccagcgta aaaatgcaaa atccaatact
    36721 aaatttcagc cagggataaa aatgcagggt gtaaattagc gctatcaaca acaaaatgat
    36781 actgattgcc catgcgagct ttgcccggaa cagtaagcca atggagttca ggacaagaaa
    36841 gacgccgagc ataaatagtg gggcgtttgc cagcaaggag agatccaact ctgaaaatgc
    36901 tttgatatgg aaaatatcaa gcaaattgac cgacatacca tagattgttt taaaaataag
    36961 caatccattt aaaaagacgg ccagcgcgag aatgtcgtgc cgaagggtca cccataaatt
    37021 tgttgctgtt tgtttgaatg tagcccagtg actcactgat acctctgtaa ccacaatttt
    37081 gtttaattat cttagcgtgc acattttctg aacatacatg cagcgcgtga atgtgttaaa
    37141 caatagtaga tgactttatc cgcagtaatc aaaggatttg agcgagcaac tgtacctcag
    37201 gaaaggtcat ttttcctgaa tatgctcaca tcatataaag aaatacagat aaagttatta
    37261 tctgcttgtg gtagtgaatg cactgaccgg ctataaggaa aggccaaaca agaacacggt
    37321 tgcaaaaacc gtgcccttaa atattgaatc tctattcaga acactttctt aaatggtttc
    37381 actgaaacgt gttcatagac tcctgccgct acgtacgggt cagcatcggc ccaggcctga
    37441 gctgcttcca gcgattcaaa ttcagcaata acggttgagc cagtaaatcc cgcagcccct
    37501 ggatcgttac tgtctaccgc tggcattgga ccagctgtca acaaacgacc ttcatcatgc
    37561 agtaactgta aacgtgctaa atgtgccgga cgaacggaaa ggcgtttttc gaggctatca
    37621 gctttgtctt gagcgtaaat aacatacaac acgggcacaa ctccttgttc gggaaagttg
    37681 taaagtacgt tatttgaaag ggcgaagatc tgcaacggaa agatgatgtc tttgttaaga
    37741 ccatgcataa attaaggtca attacgccaa aaatgacatt ttcactgatc ctgatcgtct
    37801 tgccttattg aatatgattg ctatttgcat ttaaaatcga gacctggttt ttctactgaa
    37861 atgattatga cttcaatgac ccttgaatga agtctattcg gttttctaag aaacctgtta
    37921 aaaacaggac aatatcaggt gaatgactat gcaatttaaa ggcattttcc caagtatcta
    37981 tgcaatccta cacaaattct atgcagtatc gacatagccc ctttttatca taacttattg
    38041 aaatatataa agaatctgtg aagtctcttt tcaggaaact atgcagggtg ttagtcgttc
    38101 ctctccagac acttggaaaa tcgctattta caggaatata taacgatatc tatgcagttg
    38161 gtcacataga tttacagttg caagagataa caatcagcta tgtgaaagtt cgaaagtgat
    38221 gtgtatcagt gttcaggaga ttttacgtag gacacgctta gagagtggat acaaaaaagc
    38281 ccccatgaag gaggccatga atctatatag gtgatgagaa attattcagc tttaatacgc
    38341 tgtacagttg acttggcaac gttgaattga gcggctactt tagcgattga actaccagca
    38401 gcaagagcag ctttaatacc ttctctgtca atcgctttac cgttacccct tccaactaca
    38461 cgaccagcag ctttagcagc ttcatagcct tctcgttgac gctcaagcat cattttacgt
    38521 tcagcttcag ccactgctga aaagattgtg agaatcatct tagacgtggg gttatcgtca
    38581 ccagttatca gaccttcttt gtaaaagtga accttgatac ctttctgtga aagtttatcc
    38641 accagcgtta atacatccac ggtagaacgc cctaaacgtg acaagtcgtg tacatggata
    38701 acatcgcctt cacgaacata atcgagcata gcctttagtt gtggacggtc tgtattcttc
    38761 ccagatgctt tatcagtaaa taccttatcc agtacgaccc cttcaagttg acggtctgta
    38821 atctgctgga ttgatgaaac tcgaatataa ccaatgttag ccataatata ctcatttgcc
    38881 ttactcattt gatggattga gtataacgta ccgataaagt gttttgcaag gctaatcggt
    38941 atggttttta cagggggtta gctatacctt tttagtatgc tatatcggta tgcctaagag
    39001 atggagatgc ctttacagca actcacatag aaagtcaata gatatttggc ttttttgcaa
    39061 agggggtcac atagctggtg tgacgggtac ttagcaggta tacatagcct tgtgatattt
    39121 ttgaaagatt tggttgaaga gacttagaag agacctgatt attttttata aaaattttca
    39181 gactctgaaa agttactgta cagattttat acaaattaaa aagaactccc gtaggagtcc
    39241 cttatagttg attcggttta gtgaataaac ctcatagtcg atttttaacg tggctacgat
    39301 aatccaccca tacttaacca taccccacct tacttaacca taccccaccc atacttaacc
    39361 ataccccacc ttacctagcc agaccaagcc acaggaaggc gtagagaaac cgttaaggtg
    39421 tctgtacagt tacgtcttaa acaaccatca cagtgatgtc aaatagttct tttaagtagg
    39481 aggggttccc ctatggtcac catatcccct ctctcgctta gtgagctaca cagaacctag
    39541 agaacatgcc ttcacagcat ctgtatcagg tcaactataa gaggtctgga tattaccttg
    39601 taagattctt agaagtgatt atgtagatag ttaggaaggg gtgtttaacg ggagaagaga
    39661 tacgatataa cccgaagggg agagtatcat cttaacagtg actgtaagag atacctgaaa
    39721 agatacttaa cagaactacc aagaagagag ggaacgataa gaccagaggt agtgaccttg
    39781 ttaaacagtt cgtttcaaag ctcttaagaa tctgttaagt aaggtcatgt gaacaatctt
    39841 accattttgt caatgctttt gtctttgacc taaatcaata aaatgtatcg tttgacgtgc
    39901 ttttaaacaa agtagctaaa aaatcttttt agaggggcgc ttcgcttggg gtcactatgt
    39961 tctttctctc ccgttaagag gggagttaca gggcatttca aagccctgat aaggtaagcc
    40021 cgatgataac agaaacagag ggcaaaacca cttatcaaca ctgtgaacga ataacgtaaa
    40081 gggctggtta agaaggtcgt ttgagaggtc ggttaagaaa ggagcttccc tctctggggt
    40141 tatcgctctt ctcccgatta gtggggcggt taagaagacc tctgaagttt ctctgtgaag
    40201 gtgctgaaca gctattatat atggctaatt acaactcatt gaaatataag catttttaga
    40261 agttactgtt aaggttacag agttaactgt gaagagactt gtcagttctc tatatatggc
    40321 taattacaac ttattgaaaa ataagaactt ttagaaatta ctgtcagaga ggtgaatact
    40381 tgatagatac agccttccgg ttctgtcaag atatttttta atagatagca caaaatgcta
    40441 aagatacccc tataccatct cgtacagggg gatttgaagg gagtttagcg gggttctgtg
    40501 tgattgtctg ttctggtcct gtccttgagg tcaaacgacc attcacgacc aaacaatctg
    40561 aacacgataa acactctgac gatgaaatag cgaagtagca gacctgcaat aagtccaata
    40621 cctccaccag cccatacatc aggtgacccc agttcaggag ggagatttac cattcaatgt
    40681 accttctgtg tgcaatgcaa aaaacatgtg acatacatag ttgattcggt ttatcgaata
    40741 aacctcatag ccacgccttt atattttccc tctcccataa acccattata ccataaatgt
    40801 taataaattg ttaaaaaata cttgacatta gtctttgaaa ctgctagtat tgtatatata
    40861 gttaacagga aattaacaaa cattaagagg gtcagaatat gaatgagaga tgcagaattt
    40921 agagcgatgc ttcaggcatc aaaagaacgc aacaagcaca actcctacgc ttacacaaac
    40981 aatcccacca gctacgaatt acccaagttc accaagaaag aacgcaaagg cattgacgaa
    41041 gtaattcggg caattacacc gaggagtcgt tatatgccaa ccagaaagag cacgaagaac
    41101 actattaaaa attatctggc taactttgat tcttacgaac aactaccaag taagcttgat
    41161 gatgtaatta tcggattctg tagaagtgaa ggtcacccaa aatacaacag aaagctattt
    41221 tatattctaa agaatcttga tgaaattaac tcagctaccg tgacaaatca tcttcagcga
    41281 caggcaacca gacttagtta cgaattacca agcgataaat attgcgcttt gcttgctgtg
    41341 atgtgcgcga aattaattgg cattgttgaa catcatattg ccgttgggaa tattgaacca
    41401 atggaaaacg agcaaccaga tttcgagttt gacccctatt tagttacaga ggaattttaa
    41461 atgaataaac acacattaac ccgtatttca gaggaagctt ttaacgagct taacagaatt
    41521 aaacgagcaa ctaacttgcc tcatcagact gttatgcagc ttgcaattgc taaagaagtc
    41581 actgagtcgg atttacttaa atatccagtc tctaaaggtc gtaagcacat ccgaattact
    41641 acggacgctt tagatacttt gaaggcactt aacagcttta aaattgatat tgcccgacta
    41701 ttgagcatca agattcacaa gctatcgatg ggggtttaat gctatgcgtt acctttgaat
    41761 accacacaga taaaatgatt cgctacatct ccgacctcct gattaaagga aacggattcg
    41821 gtgacatcca taactcaaaa gatattttca ttaaagccat tggcccaaat gaaacactga
    41881 aaacagcagt taaaccggaa tggtttgaac gtcacaagat tgaattaggt tattggggtg
    41941 aggaggtttt atgaaacctt ggcatgaaga tgttagacga tattttacag aacaccttat
    42001 ctatgatgaa tccagtgatt ccctgtgctg gtctgatgga gagtcagtca cgataaatac
    42061 cgacgactac ggcaacaaaa catttaatat aggccgatat actttctacg tgaaatatgt
    42121 tgtctggttc ctttatcatg gctatcaatc caacaagcaa attatccatc gaaatggtaa
    42181 cagagccgat accagaccaa aaaatcttat gcaagtccga gactttaaga gaaattagaa
    42241 aaacagcttc tcagacgctc tcaatcgcat tctaacgcaa aaaactatct tattttaggg
    42301 tgggtaatac cactgtacag gctacccctg aaaaagactg tttagctcgt tacagagcga
    42361 ttgaggaggt ctggtaaaaa ggagatttta aaaatgaaca attacgaatt acagattttt
    42421 attgataccg acaccgccat gatgattcag gctttcactg atgtaggtgt tagcattgac
    42481 tttgataagt tgttagagtt aatgactgat aatgcggaaa gcatctctga ctttattcag
    42541 tcggtggagt ttaacgagcc tcgaatgatg ctaccaatta aagacagcaa catgaaaaga
    42601 ttggttatcg agcaaacgaa caaatacagc gttagccctg aaaaatatct caaggcggct
    42661 atagcaattt tgtacagcga taatattctg gttacggatt cgaaggtggt gcattaatgg
    42721 aattggtgat tctctgtttt gtgttgattg gtatgattgc aggtgcatct attaaagtat
    42781 aaatgttacc aatctgttaa aaagctgttg acaaataacc ttgagcatga cataattgta
    42841 tatatgggga gagcaattct ccttgaatta aaatattaat cattctacat cgatgataac
    42901 tatattctga gttggaaagg tgcaatgctt ttcgtcatgg cctttcaggt tagtctgaga
    42961 ggctatctca aaaagtgctt aatcattcat tcattgaacc ctttacagct ttgccctgct
    43021 catgagttag ggcgtttctt taagagtttt taaacagagc ttttaaagaa agtttttcct
    43081 gaaacttcgt taacgttata aagcaaacct tcaaagccct tcacagatga ggatgattcc
    43141 atgaatatcc gaatcaccta tgtttagggc ttttcttaat agagcatctt taataaatcg
    43201 ttaagttatt cttctaagtg tattgacgtt gaaggtgctc tattaagaaa taaccacact
    43261 tagaggaaat aataatgaca aacgatattt acattaatgg caaagtgatt gatagcttcg
    43321 gggactggtc accacagggt gaacatccgc tacatactat tcagcgtcaa gagcatgaca
    43381 agcgtattga gcttgagcaa tcgctaaaga tgtcaccaaa ggaaatcatc tttgtgactc
    43441 ctgaacctca agagatgcct gatatttgca agagtgaagc attacttgag cttgaaaaga
    43501 aatattaccc actgctgaaa gcacaaagaa ttaaacttga tattgcttac gacaatgtga
    43561 agaactttga agagactgaa aagccaactg attttgatat tgaagtggaa attagacaaa
    43621 atccattcgt atattactca gttgaggata atgatggttt tggtacagca agagagaata
    43681 tctcaaaagt tcttcaaaac atccctgaag gattccgttt aattgacgtt agaccagctt
    43741 cacgcggtac aggttcatat attttactgt ctgataaaac agatgaagag atttgtcagt
    43801 tagctgaaaa gaatctactt gagcgtcata gcaaaaaatt aaacagattt aagcaagagc
    43861 ttgctaacca gcttagagct atgaagcaac taatcagtga ctatgaaacg cagaagaaga
    43921 ttgctatgca ggctgatatt gagcagctta cgaagatttc tagcaaatat gcaaaggcta
    43981 tttgatatgg tgtgaggtga tgaatgattg atttacagca gcgttacgag gttattaaat
    44041 ctgtttgtga aagtttgaag ctgcaaccaa acaagccaaa gctacgaatt aagagtaagc
    44101 gccaaattat cacctcgcat aaaccaaagg ttagaaggat tccttcatgg tgtattgacc
    44161 gtgttcctgc tgatgctcaa ttaattggtg agtctggttc ttacacttat atccttcatt
    44221 aaaaatcaca aaggggagag attagccttg attggttggt ctttcccttt tttgtattta
    44281 aaagataaga ggtgaaaaat atgtaatggc acaatttaaa gttgatgact tcctgattga
    44341 gttaagcttt agctctcaga aagttttaaa aggtctggaa aaagccgaga aacaaacgat
    44401 gcaaatcgca tcaagaattg agaagcgatt gaataaagct tttaaagtta atcctacgcc
    44461 tttaaatgat tctctcaaac taatggaaaa gaatgttgat aaaactgttt ccaagattga
    44521 gcagcgtttt aaaaacacta aagcgtttaa gattaaaact gagattgagg atactttaaa
    44581 gccacttaga caaccgagac agccacgaat tagcggcaac agagcaatca cagcggctta
    44641 ttcagcgaat atgtctaagt taaaaggctt cgaccctatt ttgcagaaat acatcaaatc
    44701 tcagttttac gggctatctg ctaaagctgg gtcaatggat aattcaaaat tcaatgagag
    44761 gttagctcag ctaaatgctt cagtcagaga agcaatcact aaagccagag gtcatacatc
    44821 caccagcaaa aacaatcaca gtgaaaatgc ttcaaatggt ttagatgtat tagctacaag
    44881 tgcaatcaaa gcaggtacag ccatttatag ttttcagaca gccttagaag cttataggaa
    44941 gattatggag gttggtctga aaaaagaagc atcacaacga gcggcacaat tcgttttagg
    45001 tgatgaaggt gctaaacgag ctacagaatt tgttaagaat cttgctgata gtagtggtgt
    45061 agaccagatt gaaacattaa gcagttttgc taagttttcc gctggtgctg gtgatatgaa
    45121 tacagaccag aaagaatcct tattttctaa tgtgattggt acatcccgac taatgggttt
    45181 aagcactgat gaaattaacg ggattctgaa agcttttgag cagatggcga gcaaaggcaa
    45241 gattcaggct gaagaattac gcggtcagtt aggggacaga atggcaggtg ctttccagtt
    45301 atttgccaga agccttggaa tgactaccga gcaattagat gcagctatga agaacggtaa
    45361 agttctttct aaagatgttc ttcctaaagt atccgctgaa atgggaagga tgattgataa
    45421 agctggtgga tgggaaaaga ttattaactc tactcagacg cagttaggcc gcctttctaa
    45481 ttcatggaat aataatatgg ccttaatgtt cgacggttca caggaaggtt taacagactt
    45541 tacaaggtca ctgacaaatt tacttaattc actgggtggg caatctaaaa atcttggtga
    45601 acattttggc gacttgatga aaagcatgtc aaacggtatt gatgatttaa ccacgattag
    45661 ctaccgagtg cagggattct ttgacagagt gacccttgct tacagagaat taaatgacac
    45721 tcaaaaagct gtagctgatg gtatcgcaaa tggcctgtta agtgcattaa agggacttgc
    45781 tggtattgtc gctgtaaggt ctggtattgg tgctgtaggt ggtatctgga acttaattag
    45841 ggctatttcc acgcttggaa atgtcgcaaa tacagcagcg ggaagaatta attcacgttc
    45901 cggtagtgtt gagggtggta aaggaaaatt atctgtagct gatgcaatta ccagagtaat
    45961 gattgttggt atggcaactg atgtgattaa ctccattgtc aaaccgttct atgaacgcca
    46021 gatgagtaag tcagataatc caattgataa aattgtgagg tcaaaggtgg aacccacaga
    46081 ccaagcattg actggtgaca tgaactcttt agccgctgtt ttatgggcta tggttcaggg
    46141 caaatcaaaa gatgttccac agttttcacc tgaagcattg aataacctga aaggtcgagt
    46201 ggaaacattc acacaagatt taaaggttat caagccgtca gtaaatattc agcctcagac
    46261 aatcaatatc acaactcaga cggtacttga tgggaaagtt atcgatgaaa ggacaacatc
    46321 acacatcaac cgtatgcagg aagataccct gattagctca gcttacccag aggaataaac
    46381 aatgctagaa ctactaatat ttattgccac acatggcaat ctattaatct ttatctagta
    46441 tgacgattca actatgaata gccgaatgct acgtgaaatc tcctgaacag atatacccac
    46501 caaaaattat ttttcacgta gcacacgctt aacagagaaa atacttatat atcaaaggct
    46561 tggttaaaaa tgattaaaat acactaagcc tttgaaatca aaggagaatt taatgattta
    46621 cactaaccaa atcaaatata gtggcaaaga tggcatctat ttccacttaa gagataatgt
    46681 agatgccttc ttaactttat cagcaactga aaatatggaa tttgatagcc ctatgcaggt
    46741 gactacacag aacatgcaat cagggcagac tgtcacagat aatgtaatgc gttcaccaag
    46801 aactatttca atcagtggtg tcgttgtagt tggctacgaa ggaagcttat tattaactcg
    46861 tcagggtcaa ttagtagaga acttcatcga cactcttgaa agctggagag accagaagca
    46921 gattatttcg gttatctgta aagatggtat taagattgat gattccatta ttacgagttt
    46981 taaagcctct aaagatgttg gtatttcaaa tggtctaaga atccagctaa cttttcagga
    47041 aattaacttt aaagctattg tagggcaaac tgatatctcg gctgcaactg gaaaagccgc
    47101 gactacgaat gatggtggtg ctaccagtaa aaagaatgcg ggtaacgtga ccactgaacg
    47161 caataacgca cctatgctga tgtgtcagga actgtacagt tactcagcgt ctgagctatc
    47221 tgatgaagcg ctaagggtcc gtagcaattg ctctaaaaat gtcacggtga aagatggtgt
    47281 aagcaccttc acagatgccg ctaatgagca ggcttcaaaa gtgcttaagt cgggtaatgc
    47341 tttacggaag tttagtgtaa atccgaataa gaagggcact tattgagaca taaaaagggg
    47401 cttcatagcc cctgaaaatt acagttgata agcgtcaata tccagtagct ctttatcagc
    47461 aatttcaaag attggtgacc catcatttag cggtaacggg tttgtaggta tggtgatttc
    47521 agtgtcgttc tgtagcgtta cagttaccga atccttaccc aatgtaagcc cttttagatg
    47581 cttggacaaa atcaactgac actcgacacg acccgcttta gttgtcaggt caatatcttt
    47641 aagctggggt agttccttat cagtgagtga agttttacgc ttcagagcgt cgatagtagt
    47701 ttgtatttct gtacgcttct ggttaagtcc cttcacctgt gctttcaact ctgtaatgtc
    47761 atccatttca agaagtaggg cggtagcttt cttgattctg gctgtgacaa tttcaacctc
    47821 atgctgtaac gctgcaatct tcctctctga ttctccatca ttccccacgt caatcatccc
    47881 cagaaaatta tcaatcatcc atcggtcaaa cggtttacgc ttcaacggtg gaacatcaca
    47941 gcgaccgtca ggattgttat tgcacctgta aacccctgca tacttattct tagtccctgt
    48001 agggtgaaca ctagccccac actgacaccg gaataatccc ttgaagatgt taatcgttaa
    48061 tgggttatca cttgcaggtg tgcggccttt acgattcttg tcgagaatct cttgagcttt
    48121 attgaacgtt gcagcatcta tagcggcttc gtagtagttc ggtatagcgg ggcggtcatt
    48181 gcgctgtgat gctggtagtg tacctatcgt cgtctctgac cttaagatag tacgcacaga
    48241 atgaacgcta aaaccattag catctttacg ccgtgagaat gaactaatgt tattagcctg
    48301 taggtgacgg gcgatgttat gcagactttc accatctagc agcagcttga aaatcagtct
    48361 tacagtctca gcgtgttcat tgcacttgaa agtatcgggg tcaatccatc cgggaaccat
    48421 ctttgtaaga cgttgttcac cagcaagggc aagctttgca cgttgtttcc acttctggct
    48481 aacacggaaa gacttctgct tagactcttg atgagctacg tagcttttaa cgcgctggat
    48541 gattgagatt cctaaatcat cggatagagc atcccttgtg tagattagcc catcctgtag
    48601 agtgtgaatc tcgataccat gagcaataat gcgattcatc aaggcttctg tttcaagatg
    48661 ttcaaggcgg cctatgcggt cgatagcttc gactagcaga attgtacctt ctggaaactc
    48721 cccagactca atacgggcta acatgtcacc aaactgacca gtaagatgct tacctttgta
    48781 accggataga ccctcatcac tgaaagacgc tactacttga gcatcgctat tcttcttcaa
    48841 ccattgcttg aacaggtcat tttgtcgtct ggttgaatct gcaccttcag cgccttgtat
    48901 agctgaactg aaccgaaggt atgttattac ggttctcacg gtgataaact cccatgcaat
    48961 tgattatcat ttaaagatga acttataaac gttatggcta atgctacaat gccgaatagc
    49021 tacaatacaa tgacccttga tttacctcgc cgcttcccct ggccgacgtt actttcggtc
    49081 tgcattcatg gtgctgttgt ggcgggtctg ctctatacct cggtacatca ggttattgaa
    49141 ctacctgcgc ctgcgcagcc aatttctgtc acgatggttg cgcctgctga tctcgaaccg
    49201 ccacaagccg ttcagccgcc accggagccg gtggtagagc cagaaccgga acctgagccg
    49261 atccccgaac caccaaaaga agcaccggcg gtcattgaaa agccgaagcc gaaacctaag
    49321 ccaaaaccga agccggtgaa aaaggtacag gagcagccaa aacgcgatgt caaacccgta
    49381 gagtcgcgtc cggcatcacc gtttgaaaat acggcacccg cacgcctgac atcaagtacg
    49441 gcaacggctg caaccagcaa gccggttacc agtgtggctt caggaccacg cgcattaagc
    49501 cgtaatcagc cgcagtatcc ggcacgagca caggcattgc gcattgaagg gcaggttaaa
    49561 gttaaatttg acgtcacgcc ggatggtcgc gtggataacg tacaaatcct ctcagccaag
    49621 cctgcgaaca tgtttgagcg tgaggtgaaa aatgcgatgc gcagatggcg ttatgagccg
    49681 ggtaagccag gcagtgggat tgtggtgaat atcctgttta aaattaacgg caccaccgaa
    49741 attcagtaag cagaaagtca aaagcctccg accggaggct tttgactatt actcaacagg
    49801 taaggcgcga ggttttcctt caggatcaac cgcgacatac ttaaataatg cttctgtcgc
    49861 tttatagcgt tgcccgattg gttcagacgc tacttttttc acccacactt caatattaat
    49921 gctgaccgat gtcgtccctt tctggacaca gcgtgcatag cagcacacca catcgccgac
    49981 cgcaaccggc cgtaagaaag tcattccttc aacccgcaca gtcactacgc gaccgtgggc
    50041 aatttctttc gccagaatag cgccgccaat atccatttgt gacattaacc aaccaccaaa
    50101 gatgtcacca ttggcattgg tatcggcggg catggctaaa gtacgtaaaa caagatcgcc
    50161 ctgagggacg ttatgtgttg tagacatggt aaaaccgact taaaaggaaa atcacaggcg
    50221 cgatgctact atgattttcc tgaggagaac agaggagata cagcgccagc cccgaaggac
    50281 tggcagtctg gttaggattt atcttcctgc ggcatgtggc ggtagatata gataccgctt
    50341 aacaatgtga agattaaggt aagggcggtc aggccaaaga ctttaaagtt gacccaaata
    50401 ttttgcggca gccagaatgc gatgtagatg tttgccagac cgcaaaggat aaagaaaaca
    50461 gcccaagcca gatttagctt cgaccatacc ggttgcggca gcgtgagttc tttacccagc
    50521 atccgctgaa ttagcggctt tttcatcacc cattggctga ctaacagggc tcccgcaaac
    50581 agagcataaa tgactgtaac cttccattta ataaactcat cattgtggaa gaacagcgtc
    50641 aagccaccga agacgaccac cagaacaaaa gtgatcaggg ccatcttctc aaccttacga
    50701 aagcgaaccc agctatagat aagcacaatc gccgtggcga cgatcagcgc cgcagtagcc
    50761 gcatagatgt cataaatctt gtaaaacgcg aaaaagacaa ccagcggtaa aaaatcaaga
    50821 aactgcttca ttttacgatt ccgtaatcaa atgcttaagg ttattggcga atcaacatat
    50881 acaggcggaa cagatagatg agcaatatgg cagaaatcag gttgctcaag gtgttcgcca
    50941 gtacggcacc aatttccggg gttaatgcgg caaaagaaga ggcaaaaagc agcaacagtg
    51001 tttttgccag caaccagctc agtactgcgg gtgccaccag acgcatattc gcccaagtca
    51061 gccgcatact gctacgcatc gaggcaaaaa tgcccatttt gtcctgtacc agcatcaccg
    51121 gtgccagggc cagtaaaatg gccatgataa ttcccggaac gaccaccagc atgatgccaa
    51181 tctgtactaa aagggtagtc agaaaaatca gaataaataa cttgggcaat atcggcgcac
    51241 tggcaccaat agctcgcagc gcactgactc tctgacccgc agacaccagc tggataatta
    51301 atattacgcc tccggcgaga atggcgttac cgattaatcc tgaaaaagtg gacgccgctg
    51361 aagcctgcag caaaatttgt tgctgttccg gtgacatatt ctgaaccagg tcgaacaacc
    51421 cactactgcc gctaacgggc acgccgtcat tgagctgcgc aagctgtgca tcactgggtg
    51481 agaaaacatg ccctaacacc actgtgataa acgcacatag caacgatacc aacagaatgg
    51541 tcataaattg attacggaag aaatttccgg tgtcacggta tacggactgc gccgtgatag
    51601 acatgcactc tccttgagtt ttatgcaggt gttaattagc gggcaattgt accctggtta
    51661 agcctcgggt ggcagcatca ggtcttgtat ggaaaagcat atctttgtaa agcggaggta
    51721 attgctggcc ttcaggcgtg ggcaaaccgc ggcaagtggc gatcgagtta atatttgcgt
    51781 agagaaaata tttaaaaatt gatttaaatc acattaacca ggattctcaa tgcaacttct
    51841 aaattaatcc agatcaataa atggtgaatt atcatatgta atgtgatcta tgtaggatca
    51901 tttgttactc caatgtaggt atattcgtca cgtttttata accataacga cggagcggat
    51961 atgaaaaagt taacagtggc ggctttggca gtaacaactc ttctttctgg cagtgccttt
    52021 gcgcatgaag caggcgaatt ttttatgcgt gcaggttctg caaccgtacg tccaacagaa
    52081 ggtgctggtg gtacgttagg aagtctgggt ggattcagcg tgaccaataa cactcaactg
    52141 ggcttgacgt ttacttatat ggcgaccgac aacattggtg tggaattact ggcagcgacg
    52201 ccgttccgcc ataaaatcgg cacccgggcg accggcgata ttgcaaccgt tcaccatctg
    52261 ccgccaacac tgatggcgca gtggtatttt ggtgatgcca gcagcaaatt ccgtccttac
    52321 gttggggccg gtattaacta caccaccttc tttgataatg gatttaacga tcatggcaaa
    52381 gaggcggggc tttccgatct cagtctgaaa gattcctggg gagctgccgg gcaggtgggg
    52441 gttgattatc tgattaaccg tgactggttg gttaacatgt cagtgtggta catggatatc
    52501 gataccaccg ccaattataa gctaggcggt gcacagcaac acgatagcgt acgcctcgat
    52561 ccgtgggtgt ttatgttctc agcaggatat cgtttttaat tccacaaaaa aacgaccccg
    52621 taatatacgg ggtcaataag gacatggcat aaagtgtatt atttcttcgc ttctacgccg
    52681 tcagtttcag agcgaattaa aaatttctca gttgtttgcg gaatatgctg aatcagccag
    52741 tcggccattt gcttttcctc atttaaaatc gcttcgatgg ttggaattga agctgtatca
    52801 ccggcatttt ttgctgctgc taatagtgag gtgtaacagg cgatttcaaa ttgctcgaag
    52861 acatatccgc taatagagcc tttgactatt tcatcagaag ggaatatacc accgattgac
    52921 tgcccaagcg cagctatttt actcatggaa tctttaatga ctgaacgtga aatgtcatta
    52981 cgatcaagaa tagtttccag ttgaacaatc tggtttttgg tttcactaag atgttgttca
    53041 atacgagcgc gtagttcagg ataattatct atacggctgg ccatggattc aagcatagat
    53101 tcggcttgct tttccattgc gtgggcgtca cgtaaccagt catgataatg ttcaatacga
    53161 ttcatgaaaa tgtcctcttt ataaaatgac taaaagttaa agttcatatt tcaggcttta
    53221 ttttcggctt tcttatttac gttattaagg gccagatcag tcagtttgat gtcggtggcc
    53281 ttttcttctt ccagggtctc tttcagaagc ttcgctgctt tacgataacc taattgttca
    53341 gccagcgtcg ctaatgtccc gtaactggca atctcataat gctcgacttt ctgtgctgcg
    53401 gcaatcagtg cggcatcacg cacttcgttt ttctcggtac tttcgatgac ctcattagct
    53461 tcttcaataa gaccttccat tgccacacat ttcatgcgct taattttcag attcgattct
    53521 gattccacaa cttgatcaat acgttcaatc tgtccatgtg tttcctcgag gtgcgcatga
    53581 aaagcctgac ttaatttttc gtttgatgtt gctcttgcga gttttgccag tgcccgggtt
    53641 aattgttttt ctgcgctgta ggtatctgaa agcaggtgaa taaatacatc ttcaatggtc
    53701 ttcatattca tatttttctc cagtgaaatc actgcgagcc atacggcccg cagatgcaat
    53761 tatctttatc agctgatatt aataattaac ggtgaatcag gatttgcctg atttattacc
    53821 accgctttgt tgaccgcctt ttttacccgc ttcagatgcg cgttgcggat catttttaaa
    53881 attaccgccg ctatgctgac cgcctttacg gcctgcgtcg gatgccttct cacggtcttc
    53941 ggcgaaattt cctgaaccac cacgatgttc ggccatgtta tttctcccgt tgcgttgcat
    54001 tgtttcatta atatgagtgt tgtgtgtcga cactcattaa aattagtcgc taatgagaat
    54061 tagtcaaatt aagcgcaacg agaagataga gggaaaatat attttgagga acattctgga
    54121 tatattaaca attacctgag gaataagtga cttagagaaa attattgatt ttactggtgt
    54181 tatgttgcgg gattaatttg tttgattata ttactgttgg gcggaaaaat gacgtaagtt
    54241 gacgttcgac cggggtaagc gaaacggtaa aaagataaat attaaatgaa tttaggattt
    54301 ttccggcttc attaaagaaa gttaaaatgc cgccagcgga actggcggct gtgggattaa
    54361 ctgcgcgtcg ccgctttcat cggttgtaca aaaactttca gtgccgccag cattttctct
    54421 ggctcattaa tatgttgctc gatgatttta acaatggccg aaccagaaat cgcgcccgca
    54481 gctcctgcat caatcgctgc ttttacctga tccggggcgg aaataccaaa cccctgcaat
    54541 ggaggtgcag cgttgtactc tttcagcttc gcaaccagat gattgagggg taacgcggcg
    54601 cggttttctg cgccggtcac gcccgctcgt gacagcaaat aggtgtaacc acgaccgtaa
    54661 gaggctatct ggcgcagcag gtcgtcatcg gcatttggcg ggcagatgaa gataggtgcg
    54721 acattatggc gcaacgcggc ctggcggaag ggcgcggact cttcaattgg cacatcggca
    54781 accagcaccg aatcgacgcc gactttctcg cactgggcat aaaactcatc aatgcctttg
    54841 ttaaacacca gattggcata catcaacagg ccaatgggaa tggtcgggtg tttctggcga
    54901 atcagtgcca gcatttcaaa acattgtgcc ggagtcacac ctgccgcaaa ggcgcgcaga
    54961 gtggcgtttt gaatggtcgg gccatccgct agagggtcgg agaaggggat acctaactcc
    55021 agcgcgtcag caccggcttc aattagcgta tcgataattt tcaatgactg ctcaatgccc
    55081 ggatcaccga gcgtgacgaa aggaacgaat gcgccttctt tgcgctcctt caactgggca
    55141 aacagagatt cgtagcgttc catcagattt cctctcgtgc tttcaaaata tcgtgaacgg
    55201 tgaaaatgtc tttatcgccg cgaccggaaa ggttaaccac cagtagctgc tctttatccg
    55261 ggttttcgcg catcattttc aacgcatggg ccagggcgtg ggaggattcc agcgccggga
    55321 tgatcccttc gtgcaggcac agcgttttga aggcttcaag ggcttcatca tcggtaatag
    55381 acacgtaatc agcgcgtcca gtgctgttaa gatacgcgtg ttgtgggccg acagacggga
    55441 aatccagtcc ggcggagatg gagtaagatt cttcaatctg cccgtcttcg gtttgcatca
    55501 tcggcgcttt cataccgaaa tagatgccca cgcgaccatg ttttaacggt gcgccgtgct
    55561 cgccagtttc gataccgtga ccacctggct ccacaccaat caggccgacg ttggtttcat
    55621 tgatgaaatc agcaaacatg ccgatggcat tcgaaccgcc gccaacacag gcgataacgg
    55681 catccggcag gcgaccttct ctttccagaa tctgcgcttt ggtttcttcg ccaatcatcc
    55741 gctgaaactc acgcacaatg gtcggataag gatgcgggcc agctgcggtg cccagcatat
    55801 agtgcgcggt ttcgtaacta ccggaccagt cgcgcagcgc ctcgttacag gcatctttca
    55861 gcgtcgcgga accgctatgc accgggatca cttccgcacc cattaagcgc atacgaaaaa
    55921 cgttaggcga ctggcgttct acgtctttgg cacccatata aatacggcat ttcaggccga
    55981 gcagggcgct ggcaagggcc gacgccacgc catgctgacc ggcaccggtt tcggcgatga
    56041 tttcggtttt acccatccgc ttcgccagta aagcctgacc gagcacctgg ttagttttat
    56101 gcgcgccgcc gtgcagcaaa tcttcacgct tgagatacag agtggtgttc gtcccggctg
    56161 taatgttctg gcatttggtc agcgcggttg gacgcccggc atagtttttc agcaggtcgt
    56221 tgaactgagc ctgaaattca ggatcttttt gcgcactgac aaaagcttct tccagctggc
    56281 gcagagcagg catcaggatt tgtggcacgt acatgccgcc aaactcacca aaataggggt
    56341 taagtaatgt tgtcattgtt cctttcctta atatgcgcgc agcgtctgga aaaccgaggc
    56401 caaaagacgt gcgtctttga tgcccggttg cgactctaca gcagaattaa aatcaagtcc
    56461 ggcgcagccg gtttgtgccg cttccacgca gttatctgcg cctaagcccc ccgccagcag
    56521 aacgttgcca agcgattgac catttaatag tgaccagtcg aaacgttgcc cgcttccacc
    56581 ctggccgttg tctaaaacat atttatcaac gtgctgaagc tcgcgggcgg gcagggtttc
    56641 accgacgctt aatgctttcc agatggcaac gtgtgctggc agagcttcac gcagcgtatc
    56701 gatatacagc tgatcttcat taccatgcag ttgcactgcc gccagcgata acaccttagc
    56761 tttgtccacc acatcggcaa tatcgtgatt gcggaacacg ccaacatact gcaacggtgc
    56821 cgcagccatc acttcctgcg cctgttcaac gttgacgcaa cgcggtgatg tcgcaacaaa
    56881 aatcaaccca ccgtaaatcg cgcccgcgtc ataagctgct ttagcatctt gcccacgcgt
    56941 caggccacat actttattct cacccagcaa cacccggcgc acggcggcgt gcaaatcgtc
    57001 atgggccatc aacgccgaac caatcagaaa accgttagcg aagtggctta actcgcgcac
    57061 ctgagcgtaa gtattgatgc cggattcgct gattaccgtt acgttgtgcc ccagtttcgg
    57121 cgcaagctcg cgggtacggt tgagatcaat cgacaaatca cgcagatcgc ggttgttgat
    57181 gccaacgacc tttgccccca atgcaatggc acgctccagt tcctcttcat tactgacttc
    57241 ggtcagcaca cccatctcca gactgtgggc gacggcggca agctggcgat attgttcgtc
    57301 atccagtact gaaagcatta ataagcaggc atcagcctgg taatagcgcg ccagatagat
    57361 ctggtaagga tcgataatga agtctttaca taaaatcggc tgcggggcga tttggctgac
    57421 gatggggagg aaatcaaagc tcccctgaaa atatttctca tcagtcagca ccgaaattgc
    57481 cgaagcgtaa tgtttataaa tggcggcaat gcgtgctgga tcgaaatcat cacggatcac
    57541 gccttttgac ggcgacgctt tcttgcactc cagaataaac gccgtgcgcg caccctgtag
    57601 cgcatcataa aaatgtcgcg tgctcggctg aacctcattc tgaaaactgg ccagcggttg
    57661 ctgctgtttg cgggtttcta cccaaatcgc cttgtctgcg acgattttcg ctaaaacggt
    57721 ttgcatcatt taccctcgtg ccgccagtgc ggtaactctg tcgtaagcgg aaccactgcg
    57781 cagtacctca agaacggttt gcgcattggc ttgcagatct tcatggccat gcaggcgcat
    57841 taacatggcg acgttcgcag cgacggctgc ttcatgggcg gcgtcgcctt taccttgtaa
    57901 caagcgtgtt aaaatgtcac ggttttcttc cggtgttccg cctgccagtt gctcctggtg
    57961 gtagggagtc aggccaaaat cttcagcggt caattgatag ctcttaattt cgccgtcatg
    58021 cagctcggca acgattgtcg gcgcgtgtaa tgaaacttca tccatcccgc cgctgtgcac
    58081 caccgccgcg cgttgatacc ccagcacgcg caaggtttcg gcaatcggca gcaccagttc
    58141 cggactataa acaccaatta acgccagcgg cggatgcgcc gggttaatca atggccccag
    58201 cacattgaac agggtgcggg ttttcagttg ctggcgaacc ggcatcgcgt ggcggaatcc
    58261 ggtgtgatac ttcggcgcaa agaggaaaca tacacctaac tcatccagcg cctggcgcga
    58321 tttatcggcg ttcatatcaa gattaatacc gaacgccgcc agcagatcgg acgaaccaga
    58381 tttactggag acgctacggt tgccgtgttt cgccactttc agcccacagg ccgcggcgac
    58441 aaacgcactg gcggtagaaa tattgatact gttgctgccg tcaccgccag taccgacgat
    58501 atcagcaaac agataatccg ggcgcgggaa cggcgcggcg ttttccagta gcgcggttgc
    58561 tgctccggcg atctcgttcg ggtgctcacc gcgaattttc atgctcacca gcgccgccgc
    58621 cagttgttcc ggcttcagct cgccacgcac caccgctgaa aacagctggt ggctttcttg
    58681 ttggctaagc gtctgcgcct gatacagttt ttccagaatc ggttgcagcg tgttggctgg
    58741 ctctagtttc tgctgcgccc aggccagcgt ttgttccagc aggcgagcgc cctgggtggt
    58801 gagaatggat tccggatgga actggaatcc acaaacgcga tccgcatcgt gacgtactgc
    58861 catcaccatg ccattaaaat gggcgttgat ggttaaaccg gccggaatgt tactgccaac
    58921 cagcgagtga taacgcgcca ccggcagcgg gtttgttaat ccggcaaaca tcgcctgacc
    58981 gtcatgttca atgctcgacg ctttaccgtg aagaatttcg cccgcctgac cgacatagcc
    59041 cccgtaagct tcgacaattg cctgatgtcc gaggcaaatg ccaataatgg gcagcttgcc
    59101 acgcaagcgg gtgaggagtt ccggcataca accggcttcg ctcggcacac cggggccagg
    59161 agaaagcatc agtaccggat tgctcatcgt cgccaggcgt tcaattaagg tctgcgccgg
    59221 aatatggttg cggtaaatca ccacattatg cccattgctg cgcaactgat ctgccaggtt
    59281 gtacgtaaaa gagtcgatat tatcgagcag cagaatgtca gccatcagaa agtctcctgt
    59341 gcatgatgcg cggtggcaat agcgcgcagt acagcgcggg ctttattacg ggtttcgtcg
    59401 gcttccgact gcggaacaga atcaaggact acgccagcac cggcttgcac ggtggcgata
    59461 ccgttttcca ccagcgccga gcggatcaca atgcaggtgt cgagatcgcc atgcgcggtg
    59521 aaataaccta ccgcgccgcc gtagctgccg cggcggcgac cttccgcctc ggcaattaac
    59581 tgcatagcgc gtactttcgg cgcaccactt aacgttccca tattcataca ggcgcggtaa
    59641 gcgtgcaggg cgtcgagatc gtggcgcagc tcaccgacca cgcgggagac caagtgcatc
    59701 acgtaagagt aacggtcaac tttggtgagg tcggcgacgt agcggctgcc gggggtgcaa
    59761 atgcgtgcca gatcattacg ggcgagatcc accagcatca gatgttcaga aagctcttta
    59821 tgatcggtac gcatttccag ttcgatgcgg ctgtcgaggt ctctgtccag cgagccatcg
    59881 gcacgacgac cgcgtggacg tgttccggca atcgggtaga tctcaatctg gcggctggtg
    59941 gcgtcatact tgagcgaact ttccggcgac gcgccaaaca gggtgaaatc attatcctgc
    60001 ataaaaaaca tgtacgggct gggattactc tttttcagca cgtaataggc cgccagcggt
    60061 gacgggcagg gcagagagaa acggcgagat ggcaccacct ggaaaatttc tccagcgcga
    60121 atcgcttttt gcaacaaacg cactacgcca ccgaactctt catcgctctg attacattca
    60181 caacgcatat gcggcacgga aaccactggc agcggcggcg cggcttcggt cagttgctga
    60241 cgtagttcgt tcaggcgagc agtgagacgt tgtttttctt cttcattcgg agcaaacagg
    60301 ctggcctgaa tacgggtgct ttttttctga tggtcaatca ccatcagagt ttcagcgaga
    60361 taaaaacaga aatcagggca gttattttcc gctgacagtt gcggtaaatc ttcaaatccc
    60421 gccacaaggt cataagagaa caggccgccg aagaacattg cttctcgttc ttccttcggt
    60481 acattcaaca gattctgcaa taaacggaaa gcgtcaaaaa ccgaaaggga gcataagcga
    60541 gcgtcttcat ccagcagtgg actgacaggg gggaagcgca gcacacggca gtttggtaat
    60601 tgttcatttt ccacacccgc aggcagggcg ttatccagta gtgtcagcag ggcttcgccg
    60661 ttgccggaaa gtgcctggat tgtgacagtg tcacctaaag ctgtaatgcg cagcgcactg
    60721 tctaccagca gcaggctttt taaatcatct ttgctgtcga tatctgcgga ttccagcagc
    60781 agcgttgccg gacgatcccc acacaactgg tgaaaaagcg cggtgggatt gtcgcgataa
    60841 gcgccttcgc aggttagcag ttcgagagtc ggtttttgtg tttgcattgt tattctctaa
    60901 ttttgttcaa aaaaaagccc gctcattagg cgggctgggt atctgattgc tttacgcatg
    60961 gtgaatacac tgcccgtttc aggaagtgcg ccaccaacct ttcagtacga aaattgcttt
    61021 cattgtcgat acccttttta cgtgaacttg cgtactagtt aactagttcg atgattaatt
    61081 gtcaacagct catttcagaa tatttgccag aaccgttatg atgtcggcgc aaaaaacatt
    61141 atccagaacg ggagtgcgcc ttgagcgaca cgaattatgc agtgatttac gacctgcaca
    61201 gccataccac agcttccgat ggctgcctga cgccagaagc attggtgcac cgtgcagtcg
    61261 agatgcgcgt cggcaccctg gcgatcaccg accatgacac cacagctgca atcgcgccag
    61321 caagagagga aatttcacgt tcgggactgg cgttgaatct tattcccggc gtggaaattt
    61381 ccacggtctg ggaaaatcat gaaattcata ttgtcgggct gaatattgat attactcatc
    61441 cgctaatgtg tgagttcctc gcgcagcaga cagaacggcg caatcagcgg gcgcagctga
    61501 ttgccgaaag acttgaaaaa gcgcaaatac ctggggcgct ggaaggcgca caacgactgg
    61561 cgcagggcgg cgcagtgacg cgcggtcatt ttgcgcgttt ccttgttgag tgcggcaaag
    61621 ccagttcaat ggcggatgtc tttaaaaagt atctggcgcg cgggaaaacc ggatacgttc
    61681 cgccacagtg gtgtacaata gaacaagcta ttgatgtcat tcatcattct ggcggtaagg
    61741 cggtgctagc tcatcctggg cggtacaatc ttagtgctaa atggctgaaa agattggttg
    61801 cgcattttgc cgaacaccac ggtgacgcga tggaagtcgc gcagtgccag caatcgccca
    61861 atgaacgtac ccagctggcg gcccttgcgc gtcagcatca tttatgggca tcacaaggat
    61921 ctgattttca tcagccatgc ccgtggatcg aactgggtcg taaactctgg ctgcccgcag
    61981 gcgttgaagg cgtctggcag ctatgggaac agccgcagaa caccacagag agggaattat
    62041 gagccagttt ttttatattc atcctgataa cccacagcaa cgtctgatca accaggcggt
    62101 ggagatcgtg cgtaaaggcg gggtgattgt ttatccaact gattccggct atgcgctcgg
    62161 ctgtaaaatt gaagataaaa acgcgatgga gcgtatttgt cgtattcgcc agctgccgga
    62221 cggtcacaac tttaccctga tgtgtcgcga tctttctgaa ctctcgacct attcatttgt
    62281 tgataacgtt gcgtttcgtt taatgaaaaa caacacgccg ggcaactata ccttcatctt
    62341 gaaggggacg aaggaagtgc cacgccgtct gttgcaggaa aaacgcaaaa ccatcggtat
    62401 gcgtgtgcct tctaacccga ttgcgcaggc gttgcttgaa gcactgggcg aaccgatgct
    62461 ttccacttcg ctaatgctgc caggcagcga atttaccgaa tccgatcccg aagaaattaa
    62521 agaccgtctg gaaaaacagg tggatttgat tatccacggc ggctatctcg gacagaaacc
    62581 gacaacggtt attgatctta ccgatgatac gccggtcgtg gtgcgtgaag gcgtaggtga
    62641 tgtgaagcct ttcttataag tgcgtaactc tgtatactac gcggccttaa aatggcgcta
    62701 tacggcgcca ttgattctcc tgttcgacgc ctgtgaaggc gacaccaaaa ggaagctcta
    62761 tgagcgaaaa attacagaaa gtgctggccc gcgctggcca cggctcccgc cgtgaaatcg
    62821 aatctattat tgaagccggt cgtgtgagtg ttgatggcaa aattgctaaa ctcggcgatc
    62881 gcgttgaagt tacccctggg ctgaaaattc gtatcgatgg tcatctgatt tcggtacgtg
    62941 agtccgctga acaaatttgt cgcgttctgg cctattacaa accggaaggt gagttgtgta
    63001 cccgtaacga tccggaaggg cgtccgacgg tgtttgaccg tctgccaaag ctgcgtggcg
    63061 cacgctggat tgccgtaggt cgtctggacg ttaacacctg tggtctgctg ctgttcacca
    63121 ccgatggtga actggcaaac cgtttaatgc atccaagccg tgaagttgaa cgtgaatacg
    63181 ccgtgcgtgt atttggtcag gttgacgacg cgaaactgcg tgatttgagt cgtggcgtgc
    63241 aactggaaga tggtccggca gcttttaaaa ccatcaagtt cagcggcggc gaagggatca
    63301 accagtggta caacgtgact ctgaccgaag gccgtaaccg tgaagttcgt cgtctgtggg
    63361 aagcggttgg tgtgcaggtg agccgcctga tccgtgttcg ttacggtgat atcccactgc
    63421 caaaaggtct gccacgcggt ggctggacgg agctggacct cgcccagact aactatctgc
    63481 gcgaactggt ggagcttccg ccagaaacca gctctaaagt cgctgtagaa aaagaccgtc
    63541 gtcgcatgaa ggctaatcag attcgtcgtg cggtgaaacg tcacagtcag gtgagcggcg
    63601 gtcgtcgttc tggcgggcgt aataacggtt aatcaaagta tgccggacgt catatccggc
    63661 atttttacag attaataatc aatccctatt tgcgccttaa caccggcatc aaacgcatgt
    63721 ttgatggggc gcagctcact taccgtatcc gccagttcaa gaatatcccg atgacagcct
    63781 cgacccgtga taatcaccgt ctgttgatgt ggacgttcat ttaacgcctg caccacttct
    63841 tccagtggca aatagtcata cgccaccata tacgtcagtt catcaagcaa aaccatatcc
    63901 agtgaggaat cagcaagcat ccgctttgca tgttgccaga cttcgcggca ggcggcggta
    63961 tcagactcgc ggttttgtgt atcccaggta aagcccgttg ccatcacctg aaactcaacg
    64021 ccatgtggct ccagcagatt gcgttcgcca ttaggccagg tgcctttaat aaactgcacg
    64081 acgcctactt tttttccgtg accaactgcg cgtgttgccg taccaaatgc cgcggtggtt
    64141 ttgccttttc cattgccggt aaagacgatg ataataccgc gttcatcctg ggcctgggcc
    64201 acacgagcat ctactttttc tttcactcgc tgctgacgct gttggtagcg ttcatcactc
    64261 attgggaaat tcctggttta cggcccggtt gggcgtcaaa ggtcatgccg gttttacggc
    64321 ggctgtcatc gcccatcagc cagaggtaga gcggcatgat atcagcgggt gttttaagtt
    64381 tctgtggatc ttcggtcggg aaggcgctgg cacgcattgc ggtgcgcgta ccgcctgggt
    64441 taatgcagtt gacgcgcagg cgctgctgat attcatcggc cagtacctgc atcatccctt
    64501 cggtggcaaa tttcgacgct gcatatgcgc cccagttggc tcgtccctga cgtccaacgc
    64561 ttgatgaagt aaagaccagt gaaccggcgt ccgatttgag taataaagga agcagtgcct
    64621 gggtgagcat aaaggtggca ttaacgttga cctgtatgac gtcctgccag acctgtggat
    64681 tttgttcgct cattgggcaa acatcgccga gcaatccggc attatgcaaa acaccatcca
    64741 gacgcggata attaacggta atgcgctgtg ccagttgttg gcaatcttcg gacgtgcagg
    64801 tcagcaaatc gagaataaac cactgtggct gacgtccagt ttcttcgttt atgtggctgg
    64861 ctacctgacg taatttttct tcattacggc ccaacagaat cactgtcgca ccatagcgtg
    64921 catacgtcat cgcggcttca cggccaatcc catcgctggc tcccgtcacc aggataatgc
    64981 gatcattgag taaatcttgt tttggctggt aatgcatggc tactcctcaa cgacgttgtc
    65041 tgtcgtgctg ccagtgtact ttatgacttt ggggctttat gcctgaaaca gaagggcatt
    65101 tcaatcagcc tggggcgata acaccgcaaa atggatactt tgtcatactt tcgctgcaat
    65161 aacatctctg cgagacggct taacatgcct gttgtaaact gtgagccaaa gcgttgttta
    65221 accaaggtgg ggactcgtgg aattgttgtc tgaatatggt ttgtttttgg cgaaaatcgt
    65281 taccgttgtg ctagcgattg cggcgattgc cgccattatt gtcaatgttg ctcaacgtaa
    65341 taaacgccag cgtggcgagt tacgggtcaa caatctcagc gaacagtata aggagatgaa
    65401 agaagaactg gccgcggcgc tgatggactc acatcagcaa aaacagtggc acaaagcgca
    65461 gaagaaaaag cacaagcaag aagcgaaagc agcaaaagcg aaagccaaac tgggcgaggt
    65521 ggcaactgac agtaaacctc gcgtctgggt gctggatttt aaaggcagca tggacgccca
    65581 tgaagtgaac tcgctacgtg aagagataac ggcggtactc gcagcattca aaccgcagga
    65641 tcaggttgtg ctccgtctgg aaagccctgg tggcatggtg catggttacg ggttggcggc
    65701 ttcgcagctg cagcgtctgc gtgataaaaa cattccttta actgttacgg tagacaaagt
    65761 cgctgccagc ggcggttaca tgatggcctg tgtggcggac aaaattgttt ccgcaccgtt
    65821 tgctattgtg ggttccattg gggtggtggc gcaaatgccc aactttaacc gcttcctgaa
    65881 aagcaaagat attgatatcg aactgcacac tgccgggcag tataagcgta ctctgacgtt
    65941 gctgggtgaa aataccgaag aagggcggga gaaattccgc gaagagttga acgaaacgca
    66001 tcagttgttt aaagattttg tgaagcgtat gcgtccgtct ctggatattg aacaggtggc
    66061 aacgggtgaa cactggtacg gacaacaggc ggtagagaaa ggcctggttg atgaaatcaa
    66121 caccagtgat gaagttattc ttagcctgat ggaaggccgt gaagtggtta atgtacgcta
    66181 tatgcagcgt aaacgactca ttgaccgatt caccggcagc gcggcagaga gcgccgatcg
    66241 attgttgcta cgctggtggc agcggggtca aaagccattg atgtaaaaga caaacgcgag
    66301 gctaagacct cgcgttttgc tttaatcaac cagatgatat ttttctgaaa gcacatgggc
    66361 caggtgtttg aacatattaa acaccgcggt gcttttggct gttggcaatc cttgttcatc
    66421 taaaaagtag tcgccggtaa ataccagcac gccattacgc tgcgtgacgc cggtggcttc
    66481 aatccctgcg agcgtatcct catgctcacg aatgattttg ttggcctctt tcaacagcgt
    66541 ttcgcggtcg atgggttgtg tctctttgtt cattatttac tccttaaaca aggacattag
    66601 tctacgccag gcatggcttg cagacaaata taccacgctg gtggcaagag cgccttactg
    66661 gtaactttgg attttgcatg ctaataaagt tgcgtatcgg attttatcag gtacagtgtg
    66721 acgctttcgt caatctggca atagatttgc ttgacattcg accaaaattc cgtcgtgcta
    66781 tagcgcctgt aggccaagac ctgttaactc agtcacctga attttcgtga acagagtcac
    66841 gacaaggggt tgatatccgc agagaacgag tccatatcgg taactcgttg ccagtggaag
    66901 gtttatcaac gtgcgacgca ttcctggaag aatcaaatta ggtaaggtga atatgggtaa
    66961 agctcttgtc atcgttgagt ccccggcaaa agccaaaacg atcaacaagt atctgggtag
    67021 tgactacgtg gtgaaatcca gcgtcggtca catccgcgat ttgccgacca gtggctcagc
    67081 tgccaaaaag agtgccgact ctacctccac caagacggct aaaaagccta aaaaggatga
    67141 acgtggcgct ctcgtcaacc gtatgggggt tgacccgtgg cacaattggg aggcgcacta
    67201 tgaagtgttg cctggtaaag agaaggtcgt ctctgaactg aaacaactgg ctgaaaaagc
    67261 cgaccacatc tatctcgcaa ccgaccttga ccgcgaaggg gaagccattg catggcacct
    67321 gcgggaagtg attggtggtg atgatgcgcg ctatagccga gtggtgttta acgaaattac
    67381 taaaaacgcg atccgccagg catttaacaa accgggtgag ctgaatattg atcgtgttaa
    67441 tgcccagcag gcgcgtcgct ttatggaccg cgtggttggg tatatggttt cgccgctgct
    67501 atggaaaaag atcgctcgtg gtctgtctgc cggtcgtgtg cagtcggtgg cggttcgcct
    67561 ggtggtcgag cgtgagcgtg aaattaaagc gttcgtgccg gaagagttct gggaagtcga
    67621 tgccagcacg accacgccat ctggtggagc gttggcgttg caggtgactc atcagaacga
    67681 caaaccgttc cgtccggtca acaaagaaca aactcaggct gcggtaagtc tgctggaaaa
    67741 agcgcgctac agcgtgctgg aacgtgaaga caaaccgaca accagtaaac ctggcgctcc
    67801 ttttattacc tctacgctgc aacaagctgc cagcacccgt cttggatttg gcgtgaaaaa
    67861 aaccatgatg atggcgcagc gtttgtatga agcaggctat atcacttaca tgcgtaccga
    67921 ctccactaac ctgagtcagg acgcggtaaa tatggttcgc ggttatatca gcgataattt
    67981 tggtaagaaa tatctgccgg aaagtccgaa tcagtacgcc agcaaagaaa actcacagga
    68041 agcgcatgaa gcgattcgtc cttctgacgt caatgtgatg gcggaatcgc tgaaggatat
    68101 ggaagcagat gcgcagaaac tgtaccagtt aatctggcgt cagttcgtag cctgccagat
    68161 gaccccagcg aaatatgact ccacgacgct gaccgttggt gcgggcgatt tccgcctgaa
    68221 agcacgcggt cgtattttgc gttttgatgg ctggacaaaa gtgatgcctg cgttgcgtaa
    68281 aggcgatgaa gatcgcatct taccagcagt taataaaggc gatgctctga cgctcgttga
    68341 acttacacca gcccagcact ttaccaagcc gccagcccgt ttcagtgaag catcgctggt
    68401 taaagagctg gaaaaacgtg gtatcggtcg tccgtctacc tatgcgtcga tcatttcgac
    68461 cattcaggat cgtggctacg tgcgagtaga aaatcgtcgt ttctatgcgg aaaaaatggg
    68521 cgaaatcgtc accgatcgcc ttgaagaaaa tttccgcgag ttaatgaact acgactttac
    68581 cgcgcagatg gaaaacagcc tcgaccaggt ggcaaatcac gaagcagagt ggaaagctgt
    68641 actggatcac ttcttctcgg atttcaccca gcagttagat aaagctgaaa aagatccgga
    68701 agagggtggt atgcgcccga accagatggt tctgaccagc attgactgcc cgacttgtgg
    68761 tcgcaaaatg gggattcgca cagcgagcac cggggtattc cttggctgtt ctggctatgc
    68821 gctgccgccg aaagagcgtt gcaaaaccac cattaacctg gtgccggaaa acgaagtgct
    68881 gaacgtgctg gaaggcgaag atgctgaaac caacgcgctg cgcgcaaaac gtcgttgccc
    68941 gaaatgcggc acggcgatgg acagctatct catcgatccg aaacgtaagt tgcatgtctg
    69001 tggtaataac ccaacctgcg acggttacga gatcgaagag ggcgaattcc gcattaaagg
    69061 ttatgacggc ccgatcgttg agtgtgaaaa atgtggctct gaaatgcacc tgaaaatggg
    69121 gcgtttcggt aaatacatgg cctgcaccaa cgaagagtgt aaaaacacac gtaagatttt
    69181 acgtaacggc gaagtggcac caccgaaaga agatccggtg ccattacctg agctgccgtg
    69241 cgaaaaatca gatgcttatt tcgtgctgcg tgacggtgct gccggtgtgt tcctggctgc
    69301 caacactttc ccgaaatcgc gtgaaacgcg tgcgccactg gtggaagagc tttatcgctt
    69361 ccgcgaccgt ctgccggaaa aactgcgtta tctggccgat gcgccacagc aggatccgga
    69421 aggtaataag accatggttc gctttagccg taaaaccaaa cagcaatatg tctcttcgga
    69481 aaaagacgga aaggcgactg gctggtcagc attttatgtt gatggcaaat gggttgaagg
    69541 aaaaaaataa cctttaattc tgtcaggttt ttataaacaa agggtcgcga aagcggccct
    69601 tttttattgc atattatttt ttcttcacac ctatacacta aggctataaa tgatatagtg
    69661 gttatagtta gcaccttttt tattattaaa tcgtattagt cacccgccag gtgtgacgaa
    69721 aaaacgatgt tctgatggcg tctaagtgga tggtttaaca tgaaattaca acaacttcgc
    69781 tatattgttg aggtggtcaa tcataacctg aatgtctcat caacagcgga aggactttac
    69841 acatcacaac ccgggatcag taaacaagtc agaatgctgg aagacgagct aggcattcaa
    69901 attttttccc gaagcggcaa gcacctgacg caggtaacgc cagcaggaca agaaataatt
    69961 cgtatcgctc gcgaagtcct gtcgaaagtc gatgccataa aatcggttgc cggtgagcac
    70021 acctggccgg ataaaggctc gctgtatatc gccaccacgc atacccaggc acgctacgcg
    70081 ttaccaaacg ttatcaaagg ctttattgag cgttatcccc gcgtttcttt gcatatgcac
    70141 cagggctcgc cgacacaaat tgctgatgcc gtctctaaag gcaatgctga tttcgctatc
    70201 gccacagaag cgctgcatct gtatgaagat ttagtgatgt taccgtgcta ccactggaat
    70261 cgggctattg tagtcactcc ggatcacccg ctggcaggca aaaaagccat taccattgaa
    70321 gaactggcgc aatatccgtt ggtgacatat accttcggct ttaccggacg ttcagaactg
    70381 gatactgcct ttaaccgcgc agggttaacg ccgcgtatcg tcttcacggc aacggatgct
    70441 gacgtcatta aaacttacgt ccggttaggg ctgggggtag gggtcattgc cagcatggcg
    70501 gtggatccgg tcgccgatcc cgaccttgtg cgtgttgatg ctcacgatat cttcagccac
    70561 agtacaacca aaattggttt tcgccgtagt actttcttgc gcagttatat gtatgatttc
    70621 attcagcgtt ttgcaccgca tttaacgcgt gatgtcgttg atgcggctgt cgcattgcgc
    70681 tctaatgaag aaattgaggt catgtttaaa gatataaaac tgccggaaaa ataatttctt
    70741 gcgttatttt cggcaccttt tatgtagcga aggtgccgga atatattctc ttttgttact
    70801 tatttctata ccgtgcacaa tatttttatc cctcatattt atagggtaaa ttacctgtaa
    70861 agtagtgtct aattacccgc ctcgcaaact ccagttttca aatatctatt tcaggtcaaa
    70921 agattgaatt attcactgga gacgattcgt aaattcgctg gatttttgac taaagtttct
    70981 ttaggatttg tctcatcgta tgattaatta caccaatcgt tcaacgtctt gctgataagt
    71041 gatggcgatt atatgaggtt agcaatgcct tctggaaatc aggaaccccg ccgcgatcct
    71101 gaattaaaac gtaaagcctg gctggcggtt tttcttggtt ctgcactttt ctgggtggtt
    71161 gtcgcactgc tgatttggaa agtgtgggga taactatggt cggtcaggag caactggagt
    71221 cgtcaccatt atgccagcat agtgacaatg aaacagaaac gaaacgggaa tgttccgtcg
    71281 ttattccaga cgactggcaa ctaacatcgc agcagcaagc ctttatagaa ctgtttgctg
    71341 aagatgatca gccgaaacaa taattatcat cattcttatt acccattttt aatgaattaa
    71401 agggctttta atacaccgca gcaataacag cttgagttat ctcaacacaa aataataacc
    71461 gttaagggtg tagcctatga tcaacacaaa tatgaaatat tggtcctgga tgggcgcgtt
    71521 ttctctgtcg atgctcttct gggccgaact cctctggatc attactcact gatccttgac
    71581 cccgctgcgg cggggttgtc atttgctttg ccacaaggtt tctcctcttt tatcaatttg
    71641 ggttgttatc aaatcgttac gcgatgtttg tgttatcttt aatattcacc ctgaagagaa
    71701 tcagggcttc gcaaccctgt cattaaggag gagctatgtc gtcaacccta cgagaagcca
    71761 gtaaggacac gttgcaggcc aaagataaaa cttaccacta ctacagcctg ccgcttgctg
    71821 ctaaatcact gggcgatatc acccgtctgc ccaaatcact caaagttttg ctcgaaaacc
    71881 tgctgcgctg gcaggatggt aactcggtta ccgaagagga tatccacgcg ctggcaggat
    71941 ggctgaaaaa tgcccatgct gaccgtgaaa ttgcctaccg cccggcaagg gtgctgatgc
    72001 aggactttac cggcgtacct gccgttgttg atctggcggc aatgcgcgaa gcggttaaac
    72061 gcctcggcgg cgatactgca aaggttaacc cgctctcacc ggtcgacctg gtcattgacc
    72121 actcggtgac cgtcgatcgt tttggtgatg atgaggcatt tgaagaaaac gtacgcctgg
    72181 aaatggagcg caaccacgaa cgttatgtgt tcctgaaatg gggaaagcaa gcgttcagtc
    72241 ggtttagcgt cgtgccgcca ggcacaggca tttgccatca ggttaacctc gaatatctcg
    72301 gcaaagcagt gtggagtgaa ttgcaggacg gtgaatggat tgcttatccg gatacactcg
    72361 ttggtactga ctcgcacacc actatgatca ac
//
LOCUS       DAZUDJ010000018        63906 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.018, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000018 DAZUDJ010000000
VERSION     DAZUDJ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 63906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63906
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.018"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..108
                     /locus_tag="ACHY1N_001676"
     CDS             <1..108
                     /locus_tag="ACHY1N_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4044002.1"
                     /translation="GQERNLESISGYDKIVVKYNNWITKDNGEFELAVH"
     gene            138..638
                     /locus_tag="ACHY1N_001677"
     CDS             138..638
                     /locus_tag="ACHY1N_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CS1 type fimbrial major subunit"
                     /protein_id="HFS4044003.1"
                     /translation="MKKVFAKSLLVAAMFSVAGSALAVQKDITVTANVDAALDMTQTD
                     NTALPKAVEMQYLPGQGLQSYQLMTKIWSNDVTKDVKMQLVSPAQLVQSLDASKIVPL
                     TVTWGGEEIKADAATTFTATKIFASDALTNGSLAKNLMFAQTTKGVLETGIYRGVVSI
                     YLSQDI"
     gene            730..3414
                     /locus_tag="ACHY1N_001678"
     CDS             730..3414
                     /locus_tag="ACHY1N_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcfC E-set like domain-containing protein"
                     /protein_id="HFS4044004.1"
                     /translation="MDKKLLALLILASLSPAEATLTKIPAGFEVIAQGQQEYIEVYFS
                     GKSLGKYYAMVNLDTVTFLDPASLYNKLELDVDDQKIAHIVKEKLSQPLARHGELACG
                     YVRTDSGCGFLNTDTLEIIYNDEESSATLFINPQWNSAFDAKSLYLNPDKNTVNAFIH
                     QQDINVLAQDDYQSLSIQGNGALGITENSYIGAHWNFNGYDADDVSDSNADVSDLYYR
                     YDFLRRYYVQAGRMDNRTLFNAQGGNFTFNFLPLGAIDGMRIGSTLSYLNQAQSQQGT
                     PVMVLLSRNSRVDAYRNEQLLGSFYLNSGSQFIDTSSFPPGSYSVALKVYENNQLTRT
                     ELVPFTKTGGLTDGNAQWFLQAGKTTSQVSDDESSAYQLGVRLPLHPQYELYAGLANA
                     DDVSAFELGNNWTADLGGVGNLAISASVFRNDDGGKGDMQQANWSNPGWPTLGFYRTN
                     SDGDACTTDSRESYNALSCYESISATVSQNFVGWNMMLGYTRTQNNTDDSLRWDKQQS
                     FENNYLRQTTAQSISETVQLSASRAFVMRDWILSTSVGVFHRNDNGGDNDDNGLYLSF
                     SLSDTPTMDSNNNSHSTNVSTDYRYSEQDGDQTSWQLSHTFYNDSFSHKELGVTVGGL
                     NTDTINSAVNGRWDGQYGNVYATVSDSYDRKNHDHLSAFTGTYSSTLAVSRYGVNLGA
                     SGTDDLLGAVLVDVKGFSEQDEDSQDLQLEARVAGSRTLQLGQSDSVLFPYPGFQSGF
                     VEVNDSSQGNQQGTTNIINGAGNRELMLLPGKLRYREVSASFNYNYIGRLLLPAAVKK
                     FPIVGLNSAMLLVAEDGGFTLEINGSEKELYLLSGQQFLKCPLSVVKKRASIRYSGDV
                     TCSVVTYSQLPESIQVQAQLKQPKLRGNVQTAQREVAP"
     gene            3411..4499
                     /locus_tag="ACHY1N_001679"
     CDS             3411..4499
                     /locus_tag="ACHY1N_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CfaE/CblD family pilus tip adhesin"
                     /protein_id="HFS4044005.1"
                     /translation="MRNRLIAAILGLFGTLTGVQAAPDVTSEITYDLASGRADYYFWK
                     DEASAGNNGYMWYECSYPDLQQTCTANGNISTVQIYLTEQRSGMRWPVKLKGFKTAIV
                     SSDEAPPGCKGGKGLQTNLKDSNRSSCTEDGQHYYIYDTKFLTLYLEQTEMKNLPIGG
                     VWKGKVKLHSNSPAQDYFANITLNTLDPNHIDVFFPEFAHATPRVQLDLHPTGSVNGS
                     NYAQDLTMLDMCLYDGFNGNAISYEIMLKDEGRPAAGRRDGYFSIYRQGGTTTDEGER
                     IDYRVKMYNPETGGQIDVRNNENMVWNSINLKRVRPVVLPGIRYAVMCVPTPLTLAVD
                     KFSVMDKQAGYYMGKLSVIFTPSLPTIN"
     gene            complement(4587..5885)
                     /gene="exuT"
                     /locus_tag="ACHY1N_001680"
     CDS             complement(4587..5885)
                     /gene="exuT"
                     /locus_tag="ACHY1N_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708898.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexuronate transporter ExuT"
                     /protein_id="HFS4044006.1"
                     /translation="MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNIST
                     QQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLA
                     IARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVM
                     HSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKM
                     SVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFA
                     DLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCI
                     GGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSP
                     LFAVLAVFDLLGALVIWTVLQNKPAIEVAQETHNDPAPQH"
     gene            6368..7780
                     /gene="uxaC"
                     /locus_tag="ACHY1N_001681"
     CDS             6368..7780
                     /gene="uxaC"
                     /locus_tag="ACHY1N_001681"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFS4044007.1"
                     /translation="MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAED
                     YRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYH
                     WTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
                     IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADL
                     QTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGEPLSEHEVAQFK
                     TAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLL
                     SKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMER
                     QMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLG
                     EMVKNICFNNARDYFAIELN"
     gene            7795..9282
                     /gene="uxaA"
                     /locus_tag="ACHY1N_001682"
     CDS             7795..9282
                     /gene="uxaA"
                     /locus_tag="ACHY1N_001682"
                     /EC_number="4.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HFS4044008.1"
                     /translation="MQYIKIHALDNVAVALADLAEGTEVSVDNQTVTLRQDVARGHKF
                     ALTDIAKGANVIKYGLPIGYALADIAAGEHVHAHNTRTNLSDLDQYRYQPDFQDLPAQ
                     AADREVQIYRRANGDVGVRNELWILPTVGCVNGIARQIQNRFLKETNNAEGTDGVFLF
                     SHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVAAFRETLGDIDPER
                     VHFMICQQQDDEIEAGIEHLHQLYNVMRNDKREPGKLSELKFGLECGGSDGLSGITAN
                     PMLGRFSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIA
                     HDQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAP
                     GNDAVATSALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQL
                     IHGKAMPQLLEEFIDTIVVFANGKQTCNERNDFRELAIFKSGVTL"
     gene            9365..9916
                     /gene="ygjV"
                     /locus_tag="ACHY1N_001683"
     CDS             9365..9916
                     /gene="ygjV"
                     /locus_tag="ACHY1N_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgjV family protein"
                     /protein_id="HFS4044009.1"
                     /translation="MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVH
                     FFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFIVLTGGIGLAKFHHPVELLPVIG
                     TIVSTWALFRCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFW
                     RMQKRGIDPFKVEKTPPAVDERG"
     gene            complement(9921..11165)
                     /gene="sstT"
                     /locus_tag="ACHY1N_001684"
     CDS             complement(9921..11165)
                     /gene="sstT"
                     /locus_tag="ACHY1N_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFS4044010.1"
                     /translation="MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVG
                     LLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVF
                     SFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQL
                     LVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDDRLANSALRN"
     gene            complement(11564..12529)
                     /gene="alx"
                     /locus_tag="ACHY1N_001685"
     CDS             complement(11564..12529)
                     /gene="alx"
                     /locus_tag="ACHY1N_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family membrane protein Alx"
                     /protein_id="HFS4044011.1"
                     /translation="MNTVGTPLLWGGFAVVVAIMLAIDLLLQGRRGAHAMTMKQAAAW
                     SLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMAL
                     AHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRGG"
     gene            complement(12812..13798)
                     /gene="ygjR"
                     /locus_tag="ACHY1N_001686"
     CDS             complement(12812..13798)
                     /gene="ygjR"
                     /locus_tag="ACHY1N_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4044012.1"
                     /translation="MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFAN
                     DFSVEHLFTSLEAMAESDAIDAVYIASPNALHFSQTQLFLSHKIHVICEKPLASNLAE
                     VGAAIACARENQVVLFEAFKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
                     DGENPNTFNPSFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAHGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHI
                     NTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVIFPADSVKL"
     gene            complement(13877..14560)
                     /gene="ygjQ"
                     /locus_tag="ACHY1N_001687"
     CDS             complement(13877..14560)
                     /gene="ygjQ"
                     /locus_tag="ACHY1N_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001183047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HFS4044013.1"
                     /translation="MQPRLLLRICFSRRTLKIGCLLLLIAGATIFIADRVMVNASKQL
                     TWSDVNAVPERNVGLLLGARPGNRYFTRRIDTAAALYHAGKVKWLLVSGDNGRKNYDE
                     ASGMQQALIAKGVPAKVIFCDYAGFSTLDSVVRAKKVFGENHITIISQEFHNQRAIWL
                     AKQYSIDAIGFNAPDLNMKHGFYTQLREKLARVSAVIDAKILHRQPKYLGPSVMIGPF
                     SEHGCPAKE"
     gene            complement(14637..15140)
                     /gene="ygjP"
                     /locus_tag="ACHY1N_001688"
     CDS             complement(14637..15140)
                     /gene="ygjP"
                     /locus_tag="ACHY1N_001688"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HFS4044014.1"
                     /translation="MNNLTYLQGYPEQLLSQVRTLINEQRLGDVLAKRYPGTHDYATD
                     KALWQYTQDLKNQFLRNAPPINKVMYDNKIHVLKNALGLHTAVSRVQGGKLKAKAEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKEHNKAFYQLCCHMEPQYHQLEFDTRLWLTQL
                     SLGQDKI"
     gene            15225..16361
                     /gene="rlmG"
                     /locus_tag="ACHY1N_001689"
     CDS             15225..16361
                     /gene="rlmG"
                     /locus_tag="ACHY1N_001689"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417555.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008990 - rRNA
                     (guanine-N2-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HFS4044015.1"
                     /translation="MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEI
                     RGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTAD
                     YPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRMNVETNM
                     PEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKTVKLGRRR"
     gene            16552..16635
                     /locus_tag="ACHY1N_001690"
                     /pseudo
     CDS             16552..16635
                     /locus_tag="ACHY1N_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311992.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HigB family
                     toxin"
     gene            16632..17048
                     /gene="higA"
                     /locus_tag="ACHY1N_001691"
     CDS             16632..17048
                     /gene="higA"
                     /locus_tag="ACHY1N_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HigA"
                     /protein_id="HFS4044016.1"
                     /translation="MIAIADILQAGEKLTAVAPFLAGIQNEEQYAQALELVDHLLLND
                     PENPLLDLVCAKITAWEESAPEFAEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIG
                     SKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID"
     gene            complement(17093..19111)
                     /gene="fadH"
                     /locus_tag="ACHY1N_001692"
     CDS             complement(17093..19111)
                     /gene="fadH"
                     /locus_tag="ACHY1N_001692"
                     /EC_number="1.3.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
                     /protein_id="HFS4044017.1"
                     /translation="MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDGAERLAAFY
                     AERARHGVALIVSGGIAPDLTGVGMEGGAMLNDASQIPHHRTITEAVHQEGGKIALQI
                     LHTGRYSYQPHLVAPSALQAPINRFVPHELTHEEILQLIDDFAHCAQLAREAGYDGVE
                     VMGSEGYLINEFLTLRTNQRSDQWGGDYRNRMRFAVEVVRAVRERVGNDFIIIYRLSM
                     LDLVEDGGTFAETVELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFTWVTRKL
                     KGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINT
                     CIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAIN
                     AAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYHRMIEVTGVTLKLNHTVT
                     ADQLQAFDETILASGIVPRVPPIDGIDHPKVLSYLDVLRDKAPVGNKVAIIGCGGIGF
                     DTAMYLSQPGESTSQNIARFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKAS
                     KPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVINGETQVLAVDNVVIC
                     AGQEPNRALAQPLIDSGKTVHLIGGCDVAMELDARRAIAQGTRLALEI"
     gene            complement(19437..21788)
                     /gene="ygjK"
                     /locus_tag="ACHY1N_001693"
     CDS             complement(19437..21788)
                     /gene="ygjK"
                     /locus_tag="ACHY1N_001693"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004555 - alpha,alpha-trehalase activity
                     [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFS4044018.1"
                     /translation="MKIKTILTPVTCALLISFSAHAANADNYKNVINRTGAPQYMKDY
                     DYDDHQRFNPFFDLGAWHGHLLPDGPNTMGGFPGVALLTEEYINFMASNFDRLTVWQD
                     GKKVDFTLEAYSIPGALVQKLTAKDVQVEMTLRFATPRTSLLETKITSNKPLDLVWDG
                     ELLEKLEAKEGKPLSDKTIAGEYPDYQRKISATRDGLKVTFGKVRATWDLLTSGESEY
                     QVHKSLPVQTEINGNRFTSKAHINGSTTLYTTYSHLLTAQEVSKEQMQIRDILARPAF
                     YLTASQQRWEEYLKKGLTNPDATPEQTRVAVKAIETLNGNWRSPGGAVKFNTVTPSVT
                     GRWFSGNQTWPWDTWKQAFAMAHFNPDIAKENIRAVFSWQIQPGDSVRPQDVGFVPDL
                     IAWNLSPERGGDGGNWNERNTKPSLAAWSVMEVYNVTQDKAWLAEMYPKLVAYHDWWL
                     RNRDHNGNGVPEYGATRDKAHNTESGEMLFTVKKGNKEETQSGLNNYARVVEKGQYDS
                     LEIPAQVAASWESGRDDAAVFGFIDKEQLDKYVANGGKRSDWTVKFAENRSQDGTLLG
                     YSLLQESVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLADYINTCMFDPTTQ
                     FYYDVRIEDKPLANGCAGKPIVERGKGPEGWSPLFNGAATQANADAVVKVMLDPKEFN
                     TFVPLGTAALTNPAFGADIYWRGRVWVDQFWFGLKGMERYGYRDDALKLADTFFRHAK
                     GLTADGPIQENYNPLTGAQQGAPNFSWSAAHLYMLYNDFFRKQ"
     gene            complement(21805..22875)
                     /gene="ygjJ"
                     /locus_tag="ACHY1N_001694"
     CDS             complement(21805..22875)
                     /gene="ygjJ"
                     /locus_tag="ACHY1N_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgjJ"
                     /protein_id="HFS4044019.1"
                     /translation="MKLITAPCRALLALPFCYAFSAAGEEARPAEHDDTKTPAITSTS
                     SPSFRFYGELGVGGYMDLEGENKHKYSDGTYIEGGLEMKYGSWFGLIYGEGWTVQADH
                     DGNAWVPDHSWGGFEGGINRFYGGYRTNDGTEIMLSLRQDSSLDDLQWWGDFTPDLGY
                     VIPNTRDIMTALKVQNLSGNFRYSVTATPAGHHDESKAWLHFGKYDRYDDKYTYPAMM
                     NGYIQYDLAEGITWMNGLEITDGTGQLYLTGLLTPNFAARAWHHTGRADGLDVPGSES
                     GMMVSAMYEALKGVYLSTAYTYAKHRPDHADDETTSFMQFGIWYEYGGGRFATAFDSR
                     FYMKNASHDPSDQIFLMQYFYW"
     gene            complement(23009..24442)
                     /gene="ygjI"
                     /locus_tag="ACHY1N_001695"
     CDS             complement(23009..24442)
                     /gene="ygjI"
                     /locus_tag="ACHY1N_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4044020.1"
                     /translation="MSDTKRNTIGKFGLLSLTFAAVYSFNNVINNNIELGLASAPMFF
                     LATIFYFIPFCLIIAEFVSLNKNSEAGVYAWVKSSLGGRWAFITAYTYWFVNLFFFTS
                     LLPRVIAYASYAFLGYEYIMTPVATTIISMVLFAFSTWVSTNGAKMLGPITSVTSTLM
                     LLLTLSYILLAGTALVGGVQPADPITVDAMIPNFNWAFLGVTTWIFMAAGGAESVAVY
                     VNDVKGGSKSFVKVIILAGIFIGVLYSVSSVLINVFVSSKELKFTGGSVQVFHGMAAY
                     FGLPEALMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPEGIFGKKTVELNENGVPA
                     RAAWIQFLIVIPLMIIPMLGSNTVQDLMNTIINMTAAASMLPPLFIMLAYLNLRAKLD
                     HLPRDFRMGSRRTGIIVVSMLIAIFAVGFVASTFPTGANILTIIFYNVGGIVIFLGFA
                     WWKYSKYIKGLTAEERHIEATPASNVD"
     gene            complement(24505..24954)
                     /gene="ebgC"
                     /locus_tag="ACHY1N_001696"
     CDS             complement(24505..24954)
                     /gene="ebgC"
                     /locus_tag="ACHY1N_001696"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit beta"
                     /protein_id="HFS4044021.1"
                     /translation="MRIIDNLEQFRQIYASGKKWQRCVEAIENIDNIQPGVAHSIGDS
                     LTYRVETDSATDALFTGHRRYFEVHYYLQGQQKIEYAPKETLQVVEYYRDETDREYLK
                     GCGETVEVHEGQIVICDIHEAYRFICNNAVKKVVLKVTIEDGYFHNK"
     gene            complement(24951..28043)
                     /gene="ebgA"
                     /locus_tag="ACHY1N_001697"
     CDS             complement(24951..28043)
                     /gene="ebgA"
                     /locus_tag="ACHY1N_001697"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311985.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit alpha"
                     /protein_id="HFS4044022.1"
                     /translation="MNRWENIQLTHENRLAPRAYFFSYDSVAQARTFARETSSLFLPL
                     SGQWNFHFFDHPLQVPEAFTSELMADWGHITVPAMWQMEGHGKLQYTDEGFPFPIDVP
                     FVPSDNPTGAYQRIFTLSDGWQGKQTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF
                     DISAMVKTGDNLLCVRVMQWADSTYVEDQDMWWSAGIFRDVYLVGKHLTHINDFTVRT
                     DFDEAYCDATLSCEVVLENLAASPVVTTLEYTLFDGERVVHSSAIDHLAIEKLTSASF
                     AFTVEQPQQWSAESPYLYHLVMTLKDANGNVLEVVPQRVGFRDIKVRDGLFWINNRYV
                     MLHGVNRHDNDHRKGRAVGMDRVEKDLQLMKQHNINSVRTAHYPNDPRFYELCDIYGL
                     FVMAETDVESHGFANVGDISRITDDPQWEKVYVERIVRHIHAQKNHPSIIIWSLGNES
                     GYGCNIRAMYHAAKALDDTRLVHYEEDRDAEVVDIISTMYTRVPLMNEFGEYPHPKPR
                     IICEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWEWCDHGIQAQDDNGNVWYKFGGD
                     YGDYPNNYNFCLDGLIYSDQTPGPGLKEYKQVIAPVKIHALDLTHGELKVENKLWFTT
                     LDDYTLHAEVRVEGETLATQQIKLRDVAPNSEAPLQITLPQLDAREAFLNITVTKDSR
                     TRYSEAGHSIATYQFPLKENTAQPVPFAPNNARPLTLEDDRLSCTVRGYNFAITFSKM
                     SGKPTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGLWQPNHLQIMQEHLRGFAVEQ
                     SDGEVLIISRTVIAPPVFDFGMRCTYIWRIAADGQVNVALSGERYGDYPHIIPCIGFT
                     MGINGEYDQVAYYGRGPGENYADSQQANIIDIWRSTVDAMFENYPFPQNNGNRQHVRW
                     TALTNRHGNGLLVVPQRPINFSAWRYTQENIHAAQHCNELQRSDDITLNLDHQLLGLG
                     SNSWGSEVLDSWRVWFRDFSYGFTLLPVSGGEATAQSLASYEFGAGFFSTNLHSENKQ
                     "
     gene            complement(28227..29210)
                     /gene="ebgR"
                     /locus_tag="ACHY1N_001698"
     CDS             complement(28227..29210)
                     /gene="ebgR"
                     /locus_tag="ACHY1N_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator EbgR"
                     /protein_id="HFS4044023.1"
                     /translation="MATLKDIAIEAGVSLATVSRVLNDDPTLNVKEETKHRILEIAEK
                     LEYKTSSARKLQTGAVNQHHILAIYSYQQELEINDPYYLAIRHGIETQCEKLGIELTN
                     CYEHSGLPDIKNVTGILIVGKPTPALRAAACALTDNICFIDFHEPGSGYDAVDIDLAR
                     ISKEIIDFYINQGVNRIGFIGGEDEPGKADIREVAFAEYGRLKQVVREEDIWRGGFSS
                     SSGYELAKQMLAREDYPKALFVASDSIAIGVLRAIHERGLNIPQDISLISVNDIPTAR
                     FTFPPLSTVRIHSEMMGSQGVNLVYEKARDGRALPLLVFVPSKLKLRGTTR"
     gene            29429..29761
                     /gene="ygjH"
                     /locus_tag="ACHY1N_001699"
     CDS             29429..29761
                     /gene="ygjH"
                     /locus_tag="ACHY1N_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HFS4044024.1"
                     /translation="METVAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGEKTLQ
                     TVTSLVPYYSEEELMGKTVVVLCNLQKAKMRGETSECMLLCAETDDGSESVLLTPERM
                     MPAGVRVV"
     gene            complement(29803..31182)
                     /gene="ygjG"
                     /locus_tag="ACHY1N_001700"
     CDS             complement(29803..31182)
                     /gene="ygjG"
                     /locus_tag="ACHY1N_001700"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417544.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0033094 - putrescine--2-oxoglutarate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009447 - putrescine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HFS4044025.1"
                     /translation="MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKE
                     HVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPV
                     VVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKL
                     AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAM
                     RTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTG
                     MGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFG
                     GNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMA
                     IEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALA
                     AMRVSVEEA"
     gene            31600..33120
                     /gene="aer"
                     /locus_tag="ACHY1N_001701"
     CDS             31600..33120
                     /gene="aer"
                     /locus_tag="ACHY1N_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerotaxis sensor receptor Aer"
                     /protein_id="HFS4044026.1"
                     /translation="MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFT
                     LQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPM
                     VREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
                     LRWRARGVMTLMFILLAAMLWFVAAPVVTYFLCVLVVLLASACFEWQIVRPIENVARQ
                     ALKVATGERNSVEHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNSSETLAK
                     GTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAM
                     TTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQIS
                     HSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQVSAMVKHRASRLEDAVTVLH"
     gene            complement(33274..33897)
                     /gene="nfeR"
                     /locus_tag="ACHY1N_001702"
                     /gene_synonym="yqjI"
     CDS             complement(33274..33897)
                     /gene="nfeR"
                     /locus_tag="ACHY1N_001702"
                     /gene_synonym="yqjI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NfeR"
                     /protein_id="HFS4044027.1"
                     /translation="MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCG
                     GRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYP
                     TLDFLQEQSLITIREEEGGKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQ
                     NPQMKRALDNFKAVLDLHVNQSDISDAQIKKIIAVIDRAAFDITQLD"
     gene            34174..34938
                     /gene="nfeF"
                     /locus_tag="ACHY1N_001703"
                     /gene_synonym="yqjH"
     CDS             34174..34938
                     /gene="nfeF"
                     /locus_tag="ACHY1N_001703"
                     /gene_synonym="yqjH"
                     /EC_number="1.16.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent ferric chelate reductase NfeF"
                     /protein_id="HFS4044028.1"
                     /translation="MNNSPRYPQRVRNDLRFRELTVLRVERISAGFQRIVLGGEALDG
                     FTSRGFDDHSKLFFPQPDAHFVPPTVTEEGIVWPEGPRPPSRDYTPLYDELRHELAID
                     FFIHDGGVASGWAMQAQPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLET
                     LSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYF
                     IWITGEGKVVKNLSRRFEAEQYDPQRVRAAAYWHAK"
     gene            complement(34992..35067)
                     /locus_tag="ACHY1N_001704"
     tRNA            complement(34992..35067)
                     /locus_tag="ACHY1N_001704"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(35032..35034),aa:Ile,seq:cat)
     gene            35192..35698
                     /gene="mug"
                     /locus_tag="ACHY1N_001705"
     CDS             35192..35698
                     /gene="mug"
                     /locus_tag="ACHY1N_001705"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000700 - mismatch base pair DNA
                     N-glycosylase activity [Evidence IEA];
                     GO_process: GO:0006285 - base-excision repair, AP site
                     formation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HFS4044029.1"
                     /translation="MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQA
                     GFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQ
                     ALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELD
                     QALVVRGR"
     gene            complement(35777..37618)
                     /gene="rpoD"
                     /locus_tag="ACHY1N_001706"
     CDS             complement(35777..37618)
                     /gene="rpoD"
                     /locus_tag="ACHY1N_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFS4044030.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYM
                     REMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSD
                     LITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDSADDDNSIDPELAR
                     EKFAELRAQYVVTRDTIKAKGRSHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM
                     MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVS
                     EEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAK
                     KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
                     RIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISME
                     TPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGID
                     MNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(37813..39558)
                     /gene="dnaG"
                     /locus_tag="ACHY1N_001707"
     CDS             complement(37813..39558)
                     /gene="dnaG"
                     /locus_tag="ACHY1N_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFS4044031.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAG
                     SGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGF
                     APPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQY
                     GINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQ
                     LRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLS
                     TLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTT
                     MRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYR
                     GTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNE
                     ERLELWTLNQELAKK"
     gene            complement(39669..39884)
                     /gene="rpsU"
                     /locus_tag="ACHY1N_001708"
     CDS             complement(39669..39884)
                     /gene="rpsU"
                     /locus_tag="ACHY1N_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFS4044032.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            40122..41135
                     /gene="tsaD"
                     /locus_tag="ACHY1N_001709"
     CDS             40122..41135
                     /gene="tsaD"
                     /locus_tag="ACHY1N_001709"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFS4044033.1"
                     /translation="MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     NVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLR
                     AKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAEL
                     PAA"
     gene            complement(41178..42641)
                     /gene="ttdT"
                     /locus_tag="ACHY1N_001710"
     CDS             complement(41178..42641)
                     /gene="ttdT"
                     /locus_tag="ACHY1N_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-tartrate/succinate antiporter"
                     /protein_id="HFS4044034.1"
                     /translation="MKPSTEWWRYLAPLAVIAIIALIPVPAGLESHTWLYFAVFTGVI
                     VGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSV
                     IWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSA
                     RGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLL
                     IGLMKSASHATLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETEL
                     QAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSN
                     KAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTMVMVALIVVFYLLRY
                     FFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYG
                     SGYLPTVDYWRLGAIFGLIFLVLLVITGLLWMPVVLL"
     gene            complement(42690..43295)
                     /gene="ttdB"
                     /locus_tag="ACHY1N_001711"
     CDS             complement(42690..43295)
                     /gene="ttdB"
                     /locus_tag="ACHY1N_001711"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HFS4044035.1"
                     /translation="MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELK
                     RPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGK
                     GGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEF
                     GPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK"
     gene            complement(43292..44203)
                     /gene="ttdA"
                     /locus_tag="ACHY1N_001712"
     CDS             complement(43292..44203)
                     /gene="ttdA"
                     /locus_tag="ACHY1N_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008730 - L(+)-tartrate dehydratase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HFS4044036.1"
                     /translation="MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAE
                     TSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVE
                     EATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPG
                     RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPI
                     GSRHPNPKAAELELRLEEGLNRLGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTG
                     CWAHRRGTLLVHADLTFENLSHTRSAL"
     gene            44410..45342
                     /gene="ttdR"
                     /locus_tag="ACHY1N_001713"
                     /gene_synonym="dan"
     CDS             44410..45342
                     /gene="ttdR"
                     /locus_tag="ACHY1N_001713"
                     /gene_synonym="dan"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-tartrate utilization transcriptional activator
                     TtdR"
                     /protein_id="HFS4044037.1"
                     /translation="MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQIL
                     ENTLATTLLNRSARGVALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGC
                     SFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAH
                     LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVK
                     VSGHLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYR
                     EPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM"
     gene            complement(45355..45972)
                     /gene="plsY"
                     /locus_tag="ACHY1N_001714"
     CDS             complement(45355..45972)
                     /gene="plsY"
                     /locus_tag="ACHY1N_001714"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFS4044038.1"
                     /translation="MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGAT
                     NVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE"
     gene            46077..46445
                     /gene="folB"
                     /locus_tag="ACHY1N_001715"
     CDS             46077..46445
                     /gene="folB"
                     /locus_tag="ACHY1N_001715"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HFS4044039.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKS
                     DDVADCLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKPGAV
                     ARAANVGVIIERGNNLKENN"
     gene            46536..47357
                     /gene="bacA"
                     /locus_tag="ACHY1N_001716"
     CDS             46536..47357
                     /gene="bacA"
                     /locus_tag="ACHY1N_001716"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFS4044040.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPA
                     VVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGF
                     LTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF"
     gene            complement(47520..48758)
                     /gene="cca"
                     /locus_tag="ACHY1N_001717"
     CDS             complement(47520..48758)
                     /gene="cca"
                     /locus_tag="ACHY1N_001717"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused tRNA nucleotidyltransferase/2',3'-cyclic
                     phosphodiesterase/2' nucleotidase/phosphatase Cca"
                     /protein_id="HFS4044041.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDD
                     NGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLTLM
                     REMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPA
                     PARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPA
                     GVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQR
                     VEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREEL
                     TRRRIAAVASWKEQRCPKPD"
     gene            complement(48822..49442)
                     /gene="ygiM"
                     /locus_tag="ACHY1N_001718"
     CDS             complement(48822..49442)
                     /gene="ygiM"
                     /locus_tag="ACHY1N_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04211 family SH3 domain-containing protein"
                     /protein_id="HFS4044042.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDHY
                     RLVGTVNAGEEVTLLQTDANTNYAQVKDSSGRTAWIPLKQLSTEPSLRSRVPDLENQV
                     KTLTDKLTNIDNTWNQRTAEMQQKVAQSDSVINGLKEENQKLKNELIVAQKKVDAASV
                     QLDDKQRTIIMQWFMYGGGVLGLGLLLGLVLPHLIPTRKRKDRWMN"
     gene            49684..50985
                     /gene="ygiF"
                     /locus_tag="ACHY1N_001719"
     CDS             49684..50985
                     /gene="ygiF"
                     /locus_tag="ACHY1N_001719"
                     /EC_number="3.6.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HFS4044043.1"
                     /translation="MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETP
                     DNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEV
                     WPNGELPADLASRVQPLFSTDFYREKWLVAVDDSRIEIALDQGEVKAGEFAEPICELE
                     LELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAK
                     ADVEQGLEAALELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHTLMLFGGIVPRKA
                     STHLRDLLTQCEATIASAVSAVTAVYSTKTAMAKLALTEWLVSKAWQPFLDAKAQSKM
                     SDSFKRFADIHLSRHAAELKSVFCQPLGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQ
                     AWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWLHSGKR"
     gene            51008..53848
                     /gene="glnE"
                     /locus_tag="ACHY1N_001720"
     CDS             51008..53848
                     /gene="glnE"
                     /locus_tag="ACHY1N_001720"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008882 - [glutamate-ammonia-ligase]
                     adenylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HFS4044044.1"
                     /translation="MKPLSSPLQQYWQTVVERLPEPLAEKSLSAQAKSVLTFSDFVQD
                     SVIAHPEWLTELESQSPQADEWQHYAAWLQEALSNVSDEAGLMRELRLFRRRIMVRIA
                     WAQTLALVTEESILQQLSHLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGM
                     GKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGF
                     VYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELR
                     AMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQ
                     LIRGGREPSLQSRSLLPTLSVIAALHLLSENDAEQLRVAYLFLRRLENLLQSINDEQT
                     QTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSE
                     QWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLM
                     PHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIA
                     SQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQ
                     LLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNDREGRG
                     FAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFS
                     TRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQ
                     LTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIE
                     FITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHL
                     ALQELPGHVPEDCFTAERELVRASWQKWLVEE"
     gene            53896..55329
                     /gene="hldE"
                     /locus_tag="ACHY1N_001721"
     CDS             53896..55329
                     /gene="hldE"
                     /locus_tag="ACHY1N_001721"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HFS4044045.1"
                     /translation="MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVN
                     TIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASV
                     QQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMK
                     LIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAA
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNP
                     LEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANG
                     GEVLVLNFEDGCSTTNIIKKIQQDKKG"
     gene            complement(55449..55508)
                     /gene="ibsE"
                     /locus_tag="ACHY1N_001722"
     CDS             complement(55449..55508)
                     /gene="ibsE"
                     /locus_tag="ACHY1N_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsE"
                     /protein_id="HFS4044046.1"
                     /translation="MMKFVIILVVLLLLSFPTY"
     gene            complement(55825..55884)
                     /locus_tag="ACHY1N_001723"
     CDS             complement(55825..55884)
                     /locus_tag="ACHY1N_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HFS4044047.1"
                     /translation="MMKLVIILIVLLLVSFAAY"
     gene            complement(56123..57784)
                     /gene="yqiK"
                     /locus_tag="ACHY1N_001724"
     CDS             complement(56123..57784)
                     /gene="yqiK"
                     /locus_tag="ACHY1N_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFS4044048.1"
                     /translation="MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVR
                     TGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNARIAAFEA
                     ERRREAEQTRILAERQIQETEIEREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGSAAGDANTGNVGGGNLAEQAL
                     SAALSYRTQAPLIDSLLNEIGVSGGSLAALTSPLTSTTPVAENVE"
     gene            complement(57811..58440)
                     /gene="yqiJ"
                     /locus_tag="ACHY1N_001725"
     CDS             complement(57811..58440)
                     /gene="yqiJ"
                     /locus_tag="ACHY1N_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB-fold-containig protein"
                     /protein_id="HFS4044049.1"
                     /translation="MILFADYNTPYLFAISFVLLIGLLEILALICGHMLSGALDAHLD
                     HYDSITTGHISQALHYLNIGRLPALVVLCLLAGFFGLIGILLQHACIMVWQSPLSNLF
                     VVPVSLLFTIIAVHYTGKIVAPWIPRDHSSAITEEEYIGSMALITGHQATSGNPCEGK
                     LTDQFGQIHYLLLEPEEGKFFTKGDKVLIICRLSATRYLAENNPWPQIL"
     gene            58709..58909
                     /gene="glgS"
                     /locus_tag="ACHY1N_001726"
     CDS             58709..58909
                     /gene="glgS"
                     /locus_tag="ACHY1N_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HFS4044050.1"
                     /translation="MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTW
                     FCARYAWYCQQMMQARELELEH"
     gene            complement(58952..60016)
                     /gene="yqiI"
                     /locus_tag="ACHY1N_001727"
     CDS             complement(58952..60016)
                     /gene="yqiI"
                     /locus_tag="ACHY1N_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4044051.1"
                     /translation="MRYLLIVIIFIIGFSALPVWAMDCYAEHEGGNTVVIGYVPRISI
                     PSNGKKGDKIWQSSEYFMNVFCNNALPAPSPGEEYPSAWTNIMMFLPGGQDFYNQNSY
                     IFGVTYNGVDYDSTAPNAIAAPECIDIKGAGTFNNHYKNPAVCSGGPEPQLSVTFPAR
                     VQLYIKLAKNANRVNKNLVLPDEYIALEFKGMSGAGAIEVDKNLTFRIRGLNNIHVLD
                     CFVNVALEPADGVVDFGKINSRTIKNTSVSETFSVVMTKDPGAACTEQFNILGSFFTT
                     DILSDYSHLDMGNGLLLKIFHKDGTATEFNRFSQFASFSSSSAPSVTAPFRAELSANP
                     AETVVEGPFSKDVILKITYN"
     gene            complement(60018..60767)
                     /gene="yqiH"
                     /locus_tag="ACHY1N_001728"
     CDS             complement(60018..60767)
                     /gene="yqiH"
                     /locus_tag="ACHY1N_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0061077 - chaperone-mediated protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HFS4044052.1"
                     /translation="MRYLNTKNLIAAGVLLACMSSIAWGAIIPDRTRIIMNESDKGEA
                     LKLTNQSKNLPYLAQTWIEDTKGNKSRDFIVTVPPMVRLNPSEQIQIRMISQEKIAQL
                     PNDRETLFYFNVREIPPKTDKKNVMQVTMQHALKLFWRPKAIELEDDGVMSYEKVEII
                     RRNDGSIRFNNKMPYHVTLGYIGTNGITMLPQTQSLMVTPYSHADTQFKNVPSAFQVG
                     YINDFGGLSFYEINCPTVNNSCNVSVAKRDK"
     gene            complement(60783..63287)
                     /locus_tag="ACHY1N_001729"
     CDS             complement(60783..63287)
                     /locus_tag="ACHY1N_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015473 - fimbrial usher porin activity
                     [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HFS4044053.1"
                     /translation="MYKKLKLTTISELIKNIYCSLSVLIIGCASAYAVEFNKDLIEAE
                     DRENVNLSQFETDGQLPVGKYSLNALINNKRTPIHLDLQWVLIDNQTAVCLTPEQLTL
                     LGFTDEIIEVAQQNLIDGCYPIEKEKQITTYLDKGKMQLSISAPQAWLKYKDANWTPP
                     ELWDHGIAGAFLDYNLYASHYAPHQGDNSQNISSYGQAGVNLGAWRLRTDYQYDQSFN
                     NGKSQANNLDFPRIYLFRPIPAINAKLTIGQYDTESSIFDSFHFSGVSLKSDENMLPP
                     DLRGYAPQITGVAQTNAKVTVSQNNRIIYQENVPPGPFAITNLFNTLQGQLDVKVEEE
                     DGQVTQWQVASNSIPYLTRKGQIRYTTAMGKPTSVGGDSLQQPFFWTGEFSWGWLNNV
                     SLYGGSVLTNRDYQSLAAGVGFNLNSLGSLSFDVTRSDAQLHNQDKETGYSYRANYSK
                     RFESTGSQLTFAGYRFSDKNFVTMNEYINDTNHYTNYQNEKESYIVTFNQYLESLRLN
                     TYVSLARNTYWDASSNVNYSLSLSRDFDIGPLKNVSTSLTFSRINWEEDNQDQLYLNI
                     SIPWGTSRTLSYGMQRNQDNKISHTASWYDSSDRNNSWSVSASGDNDEFKDMKASLRA
                     SYQHNTENGRLYLSGTSQRDSYYSLNASWNGSFTATRHGAAFHDYSGSADSRFMIDAD
                     GAEDIPLNNKRAVTNRYGIGVIPSVSSYITTSLSVDTRNLPENVDIENSVITTTLTEG
                     AIGYAKLDTRKGYQIMGVIRLADGSHPPLGISVKDKTSHKELGLVADGGFVYLNGIQD
                     DSKLTLRWGDKSCFIQPPNSSNLTTGTVILPCISQN"
     gene            complement(63347..63898)
                     /gene="ygiL"
                     /locus_tag="ACHY1N_001730"
     CDS             complement(63347..63898)
                     /gene="ygiL"
                     /locus_tag="ACHY1N_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein"
                     /protein_id="HFS4044054.1"
                     /translation="MSAFKKSLLVAGVAMILSNNVFADEGHGIVKFKGEVISAPCSIK
                     PGDEDLTVNLGEVADTVLKSDQKSLAEPFTIHLQDCMLSQGGTTYSKAKVTFTTANTM
                     TGQTDLLKNTKETEIGGATGVGVRILDSQSGEVTLGTPVVITFNNTNSYQELNFKARM
                     ESPSKDATPGNVYAQADYKIAYE"
BASE COUNT        15508 a        16041 c        16750 g        15607 t
ORIGIN      
        1 ggtcaggaaa gaaatcttga aagcatatct ggctacgaca aaatcgttgt caaatataat
       61 aactggatca ccaaagataa tggcgagttt gaactggcgg tccattaatt atcattgtaa
      121 taaacgaagg aatagtaatg aaaaaggtat ttgcaaaatc tcttctggtc gcagcgatgt
      181 tttctgttgc aggctccgca ttggcagtac aaaaggatat tactgtaacg gccaacgttg
      241 atgccgctct ggatatgaca cagaccgata acaccgcgtt gccgaaagca gtagaaatgc
      301 aatatctgcc ggggcagggt ctgcaatctt accagttgat gaccaaaatc tggtctaacg
      361 acgttaccaa agatgtaaaa atgcagttag tttccccggc gcaactggtt caaagcctgg
      421 atgctagcaa gattgttccg ctgacagtaa cctggggcgg tgaagaaatt aaagctgatg
      481 cggcaaccac ttttaccgca accaaaatct ttgcttccga tgcgttaact aacggttctc
      541 tggctaaaaa cctgatgttt gctcaaacca ccaaaggtgt tctggagaca ggcatctacc
      601 gtggtgtagt aagcatttat ctgtctcagg atatctaatc cagataacag aattaacacg
      661 taacaaaggg aggggtagcc ctcccttatt ttaactgttt tagtatttgt tatggatttc
      721 aggattgcca tggataaaaa attactggct cttttgatcc tggcgagtct cagcccggca
      781 gaggcgacat taaccaaaat tcccgcaggg tttgaggtta ttgctcaggg acagcaggag
      841 tatatcgagg tttatttttc agggaaaagt ctcggtaaat attatgcaat ggttaatctt
      901 gataccgtaa catttcttga tccagcaagt ctatataaca agctggaact ggatgtagac
      961 gatcagaaaa tcgcgcatat agtgaaagaa aaattatcgc agccgctagc tcgccacggt
     1021 gaattggctt gcggttatgt acgtactgac tcagggtgtg gttttctgaa taccgatacg
     1081 ctggaaataa tctataatga tgaagaaagt tcggcaacgt tgtttattaa tccgcaatgg
     1141 aattcagctt tcgatgcgaa gtcattatat ttaaatccag acaaaaatac tgttaatgct
     1201 tttatacatc agcaagacat caatgttctg gcacaggatg attaccaatc gttgtctatt
     1261 cagggaaacg gtgcgctggg aataacagaa aatagttata ttggtgcaca ctggaatttc
     1321 aacggttatg atgcagatga tgtcagtgac agtaatgctg acgtcagcga tctctattat
     1381 cgttatgatt ttttacgtcg ttattatgtg caggcgggtc gcatggacaa ccgcacacta
     1441 tttaatgcac aaggcgggaa ctttaccttt aactttctgc cactcggtgc aattgatggg
     1501 atgcgtatcg ggtcgacact gagctattta aaccaggcgc aaagccagca aggaacccca
     1561 gtaatggttc tgctttcgcg caattctcgt gttgacgctt atcgtaatga gcaacttttg
     1621 ggatcgtttt atctcaatag tggttcgcaa tttattgata ccagttcctt tccgccaggc
     1681 agctacagcg tggcattaaa agtctacgaa aataaccaac tcacccgcac cgagcttgtg
     1741 ccgtttacca aaaccggcgg tctgactgac ggaaatgcgc aatggttctt acaggcaggt
     1801 aaaactacat cacaggtttc tgatgatgaa agttcagctt atcagctagg agtacgcctg
     1861 ccattacatc cgcaatatga gctctacgca gggctggcga atgccgatga tgtgagtgct
     1921 ttcgagttag gtaataactg gacggcagat ttaggcgggg tggggaatct tgcaatcagc
     1981 gccagcgtgt tccgtaacga tgacggcggc aaaggtgata tgcaacaggc caactggagt
     2041 aatccgggat ggccgacgtt gggcttttat cggaccaact ctgacggcga tgcttgtaca
     2101 accgacagca gagagagcta taacgcctta agctgttatg aaagtatttc cgcgacggtt
     2161 tcacagaatt ttgtcggctg gaatatgatg ctgggttata cccgcacaca aaataacact
     2221 gatgatagtt tgcgttggga taaacagcag agctttgaaa ataactatct tcgccagaca
     2281 acagcgcaaa gtatctctga aactgtacaa cttagcgctt cccgcgcttt tgtgatgcgt
     2341 gactggattt tgagtacgtc agtcggtgtt ttccatcgta atgacaacgg tggcgataac
     2401 gacgacaacg gcttgtactt atcgttttcg ttatctgaca cgccaacgat ggatagcaat
     2461 aacaacagcc attcaacaaa tgtgtctacg gattatcgtt atagcgaaca ggatggcgat
     2521 caaacgtcat ggcagttatc gcataccttt tataacgatt cattcagcca taaagaactt
     2581 ggcgtaaccg tcggaggcct gaacaccgat accataaaca gcgcggttaa cgggcgttgg
     2641 gatgggcaat acggaaatgt ctacgctacc gtatctgata gttatgaccg taagaatcat
     2701 gatcatcttt cggcctttac gggcacttat agctctacgc tggctgtcag tcgctatggc
     2761 gttaatttgg gagccagtgg tacagacgat ttgctgggtg cggtactggt ggatgtgaaa
     2821 ggcttctctg aacaggatga agatagtcag gatctgcaac tcgaagcgcg ggtggcaggc
     2881 agccgaactt tgcagcttgg tcaaagtgac agtgtgttgt tcccttatcc tggatttcag
     2941 tctggttttg ttgaggttaa cgacagtagc cagggcaatc agcaggggac aacaaacatc
     3001 attaacggtg cagggaatcg tgaattaatg ttgttgcctg gcaagctgcg ctatcgcgaa
     3061 gtgtctgcca gctttaacta caactatatc ggtcgtttat tactgccggc agcggtgaaa
     3121 aaattcccga ttgtggggct gaacagcgcc atgttactgg tagctgaaga tggcggattt
     3181 acacttgaaa ttaacggcag cgaaaaagag ctctatctgc tttccgggca gcaattcctt
     3241 aagtgtccac tgagtgttgt aaagaaacgc gccagcattc gttacagcgg agatgttact
     3301 tgtagtgtgg tgacttattc acaattaccg gagtcgattc aggttcaggc acagttgaaa
     3361 cagcctaaat tacgtggaaa cgttcagacg gcgcaaaggg aggttgcacc atgagaaatc
     3421 gattgattgc ggcgatattg ggcttgtttg gcacgctcac tggcgttcag gcagctcctg
     3481 acgtgacaag tgaaattacg tatgatttgg catctggtag agcggattat tacttctgga
     3541 aggatgaagc gtcggcagga aataatggat atatgtggta tgaatgttcg tatcctgacc
     3601 tccaacaaac ctgtacagct aatggaaata tatcgacagt acaaatctat ttaactgaac
     3661 aacgcagtgg gatgcgttgg ccggtaaaac tcaaaggatt taaaacagcc attgtaagta
     3721 gcgatgaagc gccgccagga tgcaaggggg gcaaagggct tcagacgaat cttaaggatt
     3781 ctaatagatc ttcatgtaca gaagatggtc aacattatta tatatacgat acaaagtttc
     3841 ttacgctcta ccttgagcag acagagatga agaatttgcc gattggtggc gtctggaagg
     3901 ggaaagttaa attacattcg aacagcccgg cccaggacta tttcgcaaat attaccctga
     3961 atacgctcga ccccaaccat attgacgtgt tcttcccgga gttcgcccac gccacgccaa
     4021 gggtgcagtt agacttgcat ccaacaggaa gcgttaacgg cagcaactac gcgcaagatc
     4081 tgaccatgtt ggacatgtgc ctgtacgatg gttttaacgg taatgccatc agttatgaaa
     4141 tcatgctcaa agatgaaggg cgaccagctg cagggcgcag agacggttac ttctctatct
     4201 atcgtcaggg agggaccacc accgacgagg gagaacgcat tgattaccgg gtcaaaatgt
     4261 acaacccgga aaccggtggg caaattgatg tgcgcaataa tgaaaatatg gtctggaaca
     4321 gcattaacct gaaacgtgtg cgtccggtgg tactgcccgg tattcgctat gccgtgatgt
     4381 gtgtgccgac acccttgact ctggcagtcg ataaattcag cgtgatggat aaacaggccg
     4441 ggtactacat gggcaaattg tcagtaatct ttacgccttc cttgccaacc atcaattaac
     4501 cctgcaaacc ggacaaacgc ttttttctat ataaacgacg aagccgtctg ataaggcggc
     4561 ttcgtcatta caacttaagt taaacgttaa tgttgcggtg cgggatcgtt atgtgtttcc
     4621 tgcgccacct caatcgccgg tttgttctgc aacacggtcc agataaccag cgcacctaac
     4681 aggtcaaata ctgccagaac tgcgaacagc gggctgaagc cgatggtgtc agccagtgca
     4741 ccgacaacca gcgcaaacag cgtacttgcc agccatgcgg acatcccggt taaaccgttc
     4801 gccgtcgcca cttcgttacg accgaacacg tcagaagaga gcgtaatcag cgcgccagac
     4861 agtgcctggt gggcaaaacc accgatacac agcagcataa ttgcgacata cgggttggtg
     4921 aacagaccga tcatacccgg gccaatcatc agcacagcac ccagcgttac gaccatctta
     4981 cgggaaacga tcaggttcac accaaaccaa cgctggaaca gcggcggcag gtaaccaccg
     5041 aggatacaac cgaggtcagc aaacagcatc ggcatccagg cgaacatcgc gatctctttc
     5101 aggttaaagc cgtaaacttt aaacatgaac agcgggatcc acgcgttaaa agtaccccag
     5161 gccggttctg ccaggaaacg cggcagcgcg ataccccaga actgacggtt acgcaggatc
     5221 tgaccaacgg acattttctt cgccgtgctc acctggtgct gggcttcctg accattaata
     5281 atatagtcgc gttcttcatc ggtcagatgc ttctggtcgc gtggatgttt atagaaaatc
     5341 agccatgcca tcgcccagat aaagctcaat gcaccggaga tgataaatgc catctgccag
     5401 ctgtgcatta cgattgccca taccaccagc ggcggcgcaa tcatcgcacc aatcgaagaa
     5461 cctacgttaa agtaacctac cgcgatggaa cgctctttcg ccgggaacca ttcggagctg
     5521 gctttcagac ccgccgggat catcgctgct tccgcggcac cgactgcacc acgagcaatc
     5581 gccaggccac cccagctacc agccagcgcg gttgcaccac agaacacggc ccacagcaca
     5641 gcaaacattg cataaccgat tttcgtaccc agcacatcca gtacatagcc cgctaccggt
     5701 tgcatgaccg tataagcagc agaataggct gcgatgatat aggaatactg ttgggtggag
     5761 atgtttaact cttccatcag agttggcgca gctgccgcca cagtgttacg cgtcaggtaa
     5821 ccaagcacgg tgccaagcgt caccagtgcg atcatatacc aacgtaaccc tttaatttta
     5881 cgcatgtaaa acctcatcgt tttgttatat ccgcaggaag cgcggccatc atcccgccag
     5941 aggctgaaga tgttagttac gaccgggtaa ccgaaaaaaa accggcacgc cccgaacgtt
     6001 gccatgaaag tttcgtgcta attcggcttc cgtaccggtt aacccgattc atctaacaaa
     6061 tgaatgaatc ggcaatttgc attccgtcga cttatgattt gcgacggcag aaagataact
     6121 tgtcatacaa ctttaaaagg tgagagccat cacaaatgtg cgaatatttg tagggacatt
     6181 acctgacgac agcgaggcca gtactggcgc ggcctgcaga gagatttacc actttgagag
     6241 taattttttt aactacgttt attgatctaa ctcacgaaaa tatcttcgga ctctggaaat
     6301 tggtgtgata actttgtcag catcgcacca taagcaagct agctcactcg ttgagaggaa
     6361 gacgaaaatg actccgttta tgactgaaga tttcctgtta gataccgaat ttgcccgccg
     6421 tctgtatcac gactacgcaa aagaccagcc gattttcgat taccattgcc atttgccgcc
     6481 gcagcagatt gcggaagact atcgttttaa aaacctgtat gacatctggc tgaaaggcga
     6541 tcactacaaa tggcgcgcta tgcgtaccaa cggtgtggcc gagcgtctgt gtaccggtga
     6601 tgcgtctgac cgtgaaaaat ttgacgcctg ggcggcgact gttccgcaca ctatcggcaa
     6661 cccgttatac cactggacgc acctcgaact gcgtcgtccg tttggtatca ctggcaaatt
     6721 gctttctccg tcaactgccg atgaaatctg gaacgaatgt aacgaactgc tggcgcagga
     6781 taacttctcc gcgcgcggca tcatgcagca gatgaacgtg aaaatggtcg gcaccaccga
     6841 tgacccgatc gattctctgg agcatcacgc agagatcgcc aaagacggct ctttcaccat
     6901 caaagtgctg ccgagctggc gtccggacaa agccttcaac atcgaacagg cgacctttaa
     6961 cgactacatg gcgaagctgg gcgaagtttc cgataccgac attcgccgct ttgctgacct
     7021 gcaaactgcc ttgaccaaac gtctggatca cttcgccgct cacggctgta aagtgtctga
     7081 ccatgcgctg gacgtggtga tgtttgctga agcgaacgaa gcggaactgg acagcattct
     7141 ggcgcgccgt ctggctggcg aacccctgag cgagcacgaa gtggcacagt tcaaaactgc
     7201 ggtactggtg ttccttggtg ccgaatatgc acgtcgcggc tgggtacagc agtaccacat
     7261 tggcgcgctg cgtaataaca acctgcgtca gttcaaactg ctggggccgg atgtaggctt
     7321 tgactccatc aacgaccgtc cgatggcgga agagttgtct aagctgctga gcaagcagaa
     7381 cgaagaaaac ctgctgccga aaaccattct ctactgcctg aacccgcgcg ataacgaagt
     7441 gctgggcacc atgatcggta acttccaggg cgaaggtatg ccgggcaaaa tgcagttcgg
     7501 ttccggctgg tggtttaacg atcagaaaga cggtatggaa cgtcagatga cccaactggc
     7561 gcagctcggt ctgctgagcc gctttgtcgg tatgctgact gacagccgta gcttcctgtc
     7621 atacacccgt cacgaatact tccgccgcat tctgtgccag atgatcggtc gctgggtgga
     7681 agcgggcgaa gcaccggcgg acatcaacct gctgggcgag atggtgaaaa atatttgctt
     7741 taacaatgcg cgtgactact tcgccattga actgaactaa ggtctggggt tgatatgcaa
     7801 tacatcaaga tccatgcgct ggataacgtc gcggtcgctt tagcagattt ggctgaaggc
     7861 acagaagtca gtgtcgataa ccagactgtt acgctgcgcc aggatgttgc tcgtggacat
     7921 aaatttgcgt taacggatat cgcaaaaggg gccaacgtca tcaaatatgg cctgccgatt
     7981 ggttatgcat tggcggatat tgcggcgggg gaacacgtcc acgcccacaa tacgcgcacg
     8041 aatctgagcg atctggatca gtatcgctat caacctgatt ttcaggatct gcctgcgcaa
     8101 gcggcagatc gtgaagtgca gatctatcgt cgcgctaacg gcgatgtcgg ggtgcgtaat
     8161 gagctgtgga tcctgccaac cgtgggctgt gtcaacggca tcgcgcggca aatccagaac
     8221 cgtttcctga aagagaccaa caacgccgaa ggtaccgacg gcgtgttcct cttcagccac
     8281 acctacggct gctcacaact gggcgacgat cacatcaaca cccgcaccat gctgcaaaac
     8341 atggtgcgcc acccgaacgc gggcgcagtg ctggtgattg gtctgggctg tgaaaacaac
     8401 caggttgccg cattccgtga aacgttgggc gatatcgatc ctgaacgcgt tcatttcatg
     8461 atctgccaac agcaggatga tgagatcgaa gccgggatcg agcatttgca tcagctgtat
     8521 aacgtgatgc gcaacgataa acgcgagcca ggcaaactca gcgaactgaa gtttggtctg
     8581 gagtgcggtg gttctgacgg tctttctggt attactgcta acccgatgct ggggcgtttc
     8641 tctgactacg tgattgctaa cggcggtact accgtactga ccgaagtgcc ggagatgttt
     8701 ggcgcagagc agttgctgat ggaccattgc cgcgacgaag caacgtttga aaaactggtc
     8761 accatggtca acgacttcaa acagtacttt attgcccatg accagccgat ctatgaaaac
     8821 ccatcgccgg ggaacaaagc gggcggtatc accacgctgg aagataaatc ccttggctgt
     8881 acccagaaag cgggttccag cgtcgtggtt gacgtgctgc gttacggcga gcgtctgaaa
     8941 acgccggggc tgaacttgtt aagtgcgccg ggtaacgatg ccgtagcgac cagcgccctg
     9001 gcgggtgcgg gctgccatat ggtgctgttc agtactggtc gtggcacgcc atacggcggc
     9061 tttgtaccga cggtgaaaat cgctaccaac agtgaactgg cggcgaagaa aaaacactgg
     9121 atcgactttg acgcgggtca gctgatccac ggtaaagcga tgccgcagtt gctggaagaa
     9181 tttatcgaca ccatcgttgt gtttgccaac ggtaaacaaa cctgcaacga gcgtaacgac
     9241 ttccgcgaac tggcgatctt caaaagcggc gtaacgctat aaagtcgaaa tgagttgtta
     9301 ataaaaaacg gcgtttcata atgtgaagcg ccgtttgctt ttccatacct gataaggatt
     9361 tatcatgacc gcgtattggc tggcccaggg cgtgggtgtc atcgcctttc tgattggtat
     9421 cacaacattt ttcaatcgtg acgaacgtcg cttcaaaaag cagctttcgg tctatagcgc
     9481 cgttattggc gtacattttt ttcttctggg cacctatccc gctggtgcca gtgccatcct
     9541 taatgccatt cgtacattga ttaccttacg cacgcgcagc ttatgggtaa tggcgatttt
     9601 tattgtgctg actggcggaa ttggcctcgc gaagttccat catcctgtcg aactattgcc
     9661 ggttatcggt acgattgtca gtacctgggc gctgttccgc tgtaaagggc tcaccatgcg
     9721 ctgcgtgatg tggttttcaa cgtgttgctg ggtgattcac aacttctggg cggggtcgat
     9781 aggcggcaca atgattgagg gtagttttct gcttatgaat ggcttgaata tcattcgttt
     9841 ctggcggatg cagaaaaggg gaattgatcc gtttaaagta gagaaaaccc ctcccgccgt
     9901 agacgaaagg ggttaaacaa ttaattacgc agggcgctat ttgccagacg atcgtcttcc
     9961 gcctggcaag ctgccgcagt gaacagcacg tcagttgaag agttcagcgc ggtttcgcaa
    10021 gagtcctgca atacgccgat gataaagccg acggcaacca cctgcatggc gatatcgttc
    10081 gaaataccga acatattaca ggccagcggg atcagcagca gagaaccccc cgccacgccg
    10141 gatgcgccac aggcacacag agaagccacc acgctcaaca gcagcgccgt gggcagatcg
    10201 accgggatac ccagcgtatt aaccgcagcc agcgtcaaca cggtaatggt gattgctgcg
    10261 ccagccatat tgatggtggc acccagcgga atagaaacgg aataggtatc gcgatccaga
    10321 ttcagctttt cacacagtgc catattcacc ggaatgttcg ccgcagagct gcgggtgaag
    10381 aaggcataca cgccgctttc gcgcaggcac agcagcacca gcgggaacgg gttacgacga
    10441 attttccacc acaccagcaa tgggttaacc accagcgcca ccagtaacat acagccaacc
    10501 agcacgacca gcagttgcgc gtagccccac agtgtggaga aaccggtggt tgccagggta
    10561 gaagaaacca gaccaaaaat accaatcggt gcgaagcgaa tgaccagttt caccataaag
    10621 gtgacggcat tcgacatatc gttgaccagg tttttggtgg tctcgttacc gtgacgcagt
    10681 gcgaaaccga ggccaattgc ccacaccagg atcccgatgt agttaccttt cagcagcgcg
    10741 tcgatggggt tggaaaccat gctcattacc agcccgcgca tcacttcgac aatgcctgac
    10801 ggcggcgaaa tatcacccgc gctactggat aaatgcaggg tagaagggaa ggcaaagctg
    10861 aagactactg cggccagagc agcagagaag gtacccagca gatagaggaa caaaataggg
    10921 cggatattgg ttttctgccc gtgctggtgg ttagcaatag atgccatcac cagcatcaac
    10981 accaggatgg gggcaacggc tttcagtgcg ccgacgaaca aagtacctaa cagaccaaca
    11041 gcttccgccg cgggttttga gatccatgcc agaagaatcc ccagaacaag gccgaccagg
    11101 atttgtttta ccaggctgcc atgagccaga cgccggaata gccccggtga acgttgcgta
    11161 gtcatttttc gatcctttca ttgtgttgtc gcacatccct ggtgcgttct gtcgacgcat
    11221 ctttcaggat gtaacaaagt gtttgcaagg tcgagtataa ggaaagttac agcttcggga
    11281 agcgaaaaat gctggatttt aaagagaggt catattttgc aacttaatgg ttacatttat
    11341 ttgacataaa aataaagcca acgtgcggct tccagactga tgacaacatc aaaaaaggac
    11401 tcggtcagtc ccctcgcccc gtttggggag agggttaggg tgaggggaac aggccagcat
    11461 cggtgcgaaa aattaccctc accccgaccc tctccctgga agggagaggg agaaaacggt
    11521 gctcatgtta atgacagggt acacggctta ggcagattaa aaattatcca ccccgctgct
    11581 tatcatgccg ataattcacc caggcgttga taataaacgt catcaccaga atgccaaaca
    11641 ccacgcccag cgagacggcg attggaatat ggtagaagtc gacaatcagc atcttgatac
    11701 cgataaacac cagaatcacc gccaggccat atttgagcat cgagaaacgc tctgctacgc
    11761 ccgccagcag gaaatacatc gcacgcaggc cgaggatcgc aaacaggttt gaggtcagca
    11821 caatgaacgg gtcagtggtc acggcgaaga tagccggaat gctatccacg gcgaaaatca
    11881 cgtcgctcaa ttccaccaga atcagtacca gcatcagcgg tgtggcgtac agcaatccat
    11941 tcttacgcac aaagaaatgc tcgttgtcga tggtgtcggt catgcgcaaa tgaccgcgta
    12001 gccagcgcac cagcggcttg tctccaatgc ctgattcatc ttcatgggcg agcgccatct
    12061 tcacgccggt aaacagcagg aaggcaccga agatatacag gatccagtcg aactgcgaaa
    12121 ttagccagct gccagtgaag atcatgatgg tacgcagaac aatcgccccg agcacgccat
    12181 acaccagcac gcggcgttgt aatgccgccg gaacagagaa atagctgaac aacatcagcc
    12241 agacaaagac gttatcgacc gccagcgatt tctcaatcag ataacctgtg agaaaggcca
    12301 gtgcctgtgg atcggcaacg gcgcgacctt cggtttgcac cagataccac cagaaagcgg
    12361 cgttaaacag taacgacagc gtcacccaga ccagcgacca ggccgcagcc tgtttcatgg
    12421 tcatggcatg tgccccacga cgcccctgca acaacaggtc gatagccagc ataatggcga
    12481 caacaacagc gaatccgccc catagcaacg gcgtgccgac agtattcata gaagttcctt
    12541 acacataaaa aaacggccaa cgtcggaaga cgtcagccgc tgctttttat gcatagacct
    12601 cgccttccgg caaggtctca cttacaacaa aaaaggaata cgtctgcgta ttcctttcgg
    12661 gttgcccggt gaccggatgt ggtttttcac acatcgtaat gacgatcgac cggcaatgaa
    12721 gttactcccc tttgcaggta acaaagtatg acagaccatt cagccagtca atggtctgtt
    12781 acataccttt tacactgttt tactttggca attatagttt tacgctatct gccggaaaaa
    12841 tcaccccagt ctggcggcgg atctcggtca gcagtttggc ggtgatgcga ctgaccgcca
    12901 gccccggatg atccaccaga tgctcatcca ccagggtagc gaacagctct gcttcgtaga
    12961 gcatggtatt aatatgctgc ggctgggtga gatcctgcat ttggctgcca cgcggcacga
    13021 agcacacttt ctggcattca gacagttttt caatcaccag cgatcctgct tcgccctgaa
    13081 tctcgctcgc caggacagaa tcactgactt ttgagtgctg caaggtgacg ctgaaatcac
    13141 cgtaatccat caccaccacg ccgtgggcat ctacaccgct tgccagcaaa ctggcggttg
    13201 cctgcacgct tttcggctca ccaaataacg ccaccgccga cgccaggcag taaaagccga
    13261 tatccataat tgaaccgtta gagaatgacg gattaaaggt gttgggattt tcaccgtcca
    13321 ggtaacgttg atagcgcgag gaatactggc aatagttgaa aaagacttta cgcaatttgc
    13381 cgactttcgg cagcgcctgg cgcagcaaat gaaagttcgg caggcaggcg gttttaaatg
    13441 cctcaaacag caccacctga ttttcccgcg cacaggcaat ggcggcaccc acttccgcca
    13501 gattcgacgc cagtggtttc tcgcaaatca catgaatttt atggctaagg aaaagttgtg
    13561 tctgggaaaa atgcagggca ttcgggctgg caatatacac cgcgtcaatg gcatcgcttt
    13621 ccgccatcgc ttccagcgag gtaaacagat gctcgacaga aaaatcattg gcgaagtgct
    13681 gagcctgctc aaggctgcgg gaatatacgg cggttaactt gtatttaccg ctctcatggg
    13741 cggcctcgac gaactggcga gtgatccagt tcgtaccaat cacagcgaaa cgtatcataa
    13801 cgcgtggata ctccataaag ggattctgtc gtcaatgtag cacgcctttt tcatcttcga
    13861 cgtgcgcaga tacgcattat tcttttgccg gacagccatg ctcactaaac ggcccaatca
    13921 tgaccgatgg cccgagatat ttcggctggc gatggaggat tttggcgtca atcacggcgc
    13981 tgacacgagc gagtttctcc cgcagttgag tataaaaacc gtgcttcata ttgaggtcag
    14041 gcgcgttaaa accgatagcg tcgatgctgt actgttttgc cagccagatg gcgcgttggt
    14101 tatgaaattc ttgcgagata atggtgatat ggttttcacc aaaaaccttt ttggcacgca
    14161 ctaccgaatc cagcgttgag aatccggcat agtcgcagaa gatcactttc gccggtacgc
    14221 ctttagcgat caaagcctgc tgcatacctg aggcttcatc gtaattttta cgtccgttat
    14281 cgccacttac cagtagccat ttcacttttc cggcgtggta caacgctgct gcggtatcaa
    14341 tacgtcgggt aaagtagcga ttacccggcc tggcccccag caataagccc acgttacgct
    14401 ccggaactgc gttgacatcg ctccaggtca gctgcttgct ggcgttgacc ataacgcgat
    14461 cggcaataaa aatggtcgct cctgctataa gcaacaacaa acagccaatc ttaagagtcc
    14521 ggcgagaaaa acaaatacgg agaagaaggc ggggctgcat ggtcgttatc cttaacgaaa
    14581 ggggggaggt cgattttagg cgctaaagaa agaaaagata acgcctgaca tcattttcag
    14641 attttgtcct gcccaagcga caactgcgtt agccacagcc gggtgtcgaa ctcaagctgg
    14701 tggtactgcg gctccatatg gcagcacaac tggtaaaacg ctttgttatg ctctttctcc
    14761 ttcaggtgcg ccagttcgtg caccacgatc atacgtaaaa acggttccgg cgcgttgcga
    14821 aacacagtag cgacgcggat ctctgctttt gctttcagct tgccgccctg cacacgagaa
    14881 acagcggtat gtaacccgag cgcgtttttt agcacatgga tcttattgtc atacatcact
    14941 ttattgatcg gcggggcatt acgcagaaac tgatttttca gatcctgagt atattgccag
    15001 agggctttat cggtggcgta gtcgtgtgtt cccggatagc gttttgccag cacatcgccc
    15061 agacgctgtt cgttaatcag cgttcgcacc tgggaaagta gctgctcggg ataaccctga
    15121 agataagtaa gattgttcat aaccgcccac gaaaaagaga aaaagggtat actcacgcac
    15181 ccttttcagg ggcaacgtcg aaattttatc attcaggagg gccgatgagc cacttagaca
    15241 acggtttccg ttcactgaca ctacaacgtt ttccggcgac ggatgacgtt aacccgctac
    15301 aggcgtggga agcggcggat gaatatttgc tgcaacagtt ggacgacaca gaaatccgcg
    15361 gcccggtgtt gatcctgaat gatgcctttg gtgcgttaag ctgcgcgctg gcggaacata
    15421 agccgtacag cattggcgac tcatacatca gtgaactggc gacgcgcgag aatttacgcc
    15481 tcaacgggat tgatgagtcg agcgtgaagt ttctcgacag caccgccgac tacccgcaac
    15541 agccgggtgt ggtgctgatc aaagtgccga aaacactggc attgctggaa cagcaactgc
    15601 gtgcgctgcg caaagtggtc acgtcggata cacgtattat tgccggtgcc aaagcccgtg
    15661 acattcacac ttccacgctg gagctgttcg agaaagtgct cggcccgacc accactacgc
    15721 tggcatggaa aaaagcgcgc ctgattaatt gcactttcaa tgaaccgccg ctggccgatg
    15781 cgccgcagac cgttagctgg aagctggaag gtactgactg gactatccac aaccatgcga
    15841 atgtcttctc ccgcaccggg ctggatattg gcgcacgctt ctttatgcaa catctgccag
    15901 agaatctcga aggtgagatt gtcgatctcg gctgtggtaa cggcgttatt ggcctgacgc
    15961 tgcttgataa aaacccgcag gcgaaagtgg tgtttgtcga tgaatcgccg atggcggtcg
    16021 cttccagccg aatgaatgtt gaaaccaaca tgccagaggc gttggatcgc tgcgagttta
    16081 tgatcaacaa cgcgctctcc ggagtggagc ctttccgctt taatgctgtg ctctgcaacc
    16141 cgccgtttca tcagcaacat gcgctgaccg ataacgtcgc ctgggagatg ttccaccacg
    16201 cccgccgctg cctgaaaatc aacggcgaac tgtatatcgt tgccaaccgt cacctggatt
    16261 acttccataa actgaagaag attttcggca actgcaccac catcgccacg aataataaat
    16321 ttgtggtgct gaaaacagtg aagctggggc gtcgtcggta agattgggag ttacctgccg
    16381 gatgcggcgt taacgcctta tccggcctac gttcagcacg ttactcccag gccggataag
    16441 acgcggcaag cgtcgcatcc ggcaatgtct gcccagttct ggaatcgcgc ttccataaaa
    16501 caaaaaatcc ctgtcaccat cctctacatt ctcttgttta gcgttgttca acgtttatgc
    16561 tacatacgtg aagttatgac gcataaagaa tacgatttct ttaccgctgt tcatcgtact
    16621 aaggggaaaa aatgattgcg attgccgaca tcttgcaagc aggagaaaag ctaactgcgg
    16681 tggcaccttt tctggcgggt attcagaacg aggaacaata cgcccaggcg ctggaactgg
    16741 tagatcatct gctgctcaac gatcctgaaa accccttgct ggatctggtg tgtgccaaaa
    16801 taaccgcgtg ggaagaatca gcgcccgaat ttgcggaatt taatgccatg gctcaagcca
    16861 tgcctggcgg tatagccgtg attcgtaccc ttatggatca atatggttta accctttccg
    16921 atctgccgga aattggcagt aaatctatgg tgtcacgcgt tttgagcggg aagaggaaat
    16981 taacgctgga acacgctaaa aaattggcaa cgcgattcgg catttctccc gccttgttta
    17041 ttgattaacg cgacgtgccg gatgcgttgc atccggcgct tcaaataacg atttaaatct
    17101 ccagcgccag ccgtgttccc tgggcaattg cccgtcgtgc gtccagctcc atagccacat
    17161 cgcagccgcc aattaaatgc acagttttcc cgctatcaat cagcggttgc gccagcgcgc
    17221 ggtttggctc ttgccctgcg cagatcacca cattgtccac tgctaatacc tgcgtttcgc
    17281 cgttgatcac cacatgcagc ccgtcatcgt caatcttctg ataacttacg cctgggatca
    17341 ttttcacacc ccgcgagagc agggtggtgc gatggatcca gccggtggtt ttgcctaacc
    17401 cctgtcccgg tttgctggct ttgcgctgga gcatcacaat ttgccgtggg ctacgcggga
    17461 tctgcattcc ctgcgggctt aagccaccag cctgttgtag gctgctgtcg atcccccact
    17521 cattacagaa cctggcgata ttctggctgg tggattcgcc cggctgactt aaatacatcg
    17581 ccgtatcaaa accaatcccg ccacaaccga tgatggcaac cttgttgcct accggcgctt
    17641 tgtcgcgcag tacatcgaga taactcaata ccttcggatg atcgatcccg tcgataggcg
    17701 gaacgcgcgg cacgatccca ctggcgagga tcgtttcatc gaacgcctgt aactgatccg
    17761 ccgtcacggt gtgattgagt ttcagcgtca cgcccgtcac ttcgatcatc cggtggtaat
    17821 agcgcagcgt ttcgtaaaac tcctctttgc cggggatctg tttggcgata ttaaactgcc
    17881 cgccgatctc gctgtgggca tcaaacaatg ttacctgatg cccacgcgcc gccgcgttaa
    17941 tggcaaacgc cagcccagca ggtcccgcac cgaccaccgc cagatttttt ttctgcacgg
    18001 caggaaggat tggcattttg gtttcgtggc aggcgcgagg attcaccagg cacgaggtga
    18061 ctttgccaac gaagatctga tcgaggcagg cctgattgca gccaatgcag gtgttgatct
    18121 catcggctcg ccccgattgc gcttttgaca gcagttccgc atcagcaaga aacggtcgtg
    18181 ccatcgacac catatcggca tcgccgcgcg agagaatgtc gtcggcaacc tgcggatcgt
    18241 taatccggtt ggtggtcacc agcggcagcg aaacgtggcc tttcagtttg cgcgtgaccc
    18301 aagtaaatgc gccgcgcggc acgggcgtgg caatggtcgg aatacgtgct tcatgccagc
    18361 caatgccggt gttgataatg gtcgcgcccg ccgcttcaat ggcctgcgcc agctctaccg
    18421 tttcggcaaa agtcccgccg tcttcgacca ggtcgagcat cgacagtcgg tagataataa
    18481 tgaagtcgtt gccgacgcgt tcgcgcaccg cacgcactac ttctacggca aatcgcatcc
    18541 ggttgcggta atcgccgccc cactggtcac tacgctgatt ggtgcgcagc gtcagaaatt
    18601 cgttgatcaa atacccttcg gaccccatta cctctacacc gtcgtatcct gcctcccgtg
    18661 ccagttgcgc gcagtgggcg aaatcgtcga tcagttgcag gatctcttca tgggtgagtt
    18721 cgtgaggaac gaaacggttg atgggggcct gcaatgcgga gggagcgacc agatgcggtt
    18781 ggtagctgta gcgcccggta tgcaaaattt gcagggctat tttgccgcct tcctgatgta
    18841 ccgcttcggt aatggtgcga tggtgtggga tctggctggc gtcgttgagc attgcgccac
    18901 cttccatgcc aacgcctgtt aaatctggtg caatgccgcc gctgacaatc agcgccacgc
    18961 cgtgacgggc gcgttcggca taaaacgctg ccagccgctc ggcaccgtcc gggtattcct
    19021 ccagcccggt gtgcattgag cccatcaaca cgcggttttt taacgtggta aaacctaaat
    19081 ccagcggggc gaacagcgac gggtagctca taaaattgtc cagtatgtaa aataattgtt
    19141 atgtggtcgg atgagttcta atttagccgt cgccggagaa aagggaaaag gggagtgcgg
    19201 ggtttgtgat gggattcaaa aagaatacgc ccggtggtaa cgccggatgc gacgcttgcc
    19261 gcgttttatc cggcctgggg gattgcacat gtagggcgga taaggcgttc acgccgcatc
    19321 cgccagtggc acggtgcaga tgccggatgc gacgcttgtc gcgttttatc cggccaggag
    19381 gattgcacat gtagggcgga taaggcgttt acgccgcatc cgccagcagt tgcaaattat
    19441 tgcttacgga aaaaatcgtt atacaacata tacaaatgcg cggcactcca ggagaaattt
    19501 ggtgcgcctt gctgtgcgcc agtcagcggg ttgtaattct cctgaattgg gccatcggcg
    19561 gttaatcctt tggcgtgacg gaagaacgta tccgccagtt tcagggcatc atcgcgataa
    19621 ccgtaacgct ccatcccttt cagaccaaac cagaactgat ccacccatac gcgcccacgc
    19681 cagtagatat cagcgccaaa agccggattg gttaacgccg ccgttcccag cgggacaaag
    19741 gtgttgaact ctttaggatc gagcatcacc ttcaccaccg cgtcggcatt ggcctgcgtt
    19801 gccgcaccgt taaacagcgg cgaccagcct tccggccctt taccgcgctc aacaatcggt
    19861 ttgcccgcgc agccgttcgc cagtggttta tcttcaatac gtacgtcata gtagaactgg
    19921 gtagtcgggt cgaacataca ggtgttgatg tagtccgcga gctgctgtgc caactggcga
    19981 tagcgtttgg cctcttctgg cttaccgagg atggttgcca tctccgccag ataatggtta
    20041 tcgctgtaca tatagctggc ctgatccacc gactcctgca atagcgagta gcccagcaac
    20101 gttccgtcct gactgcggtt ttcggcgaat ttcaccgtcc agtcgctacg tttgccgcca
    20161 ttagcgacat atttatccaa ctgttctttg tcgataaaac caaagacggc ggcatcatca
    20221 cgccccgatt cccacgacgc agcgacctgt gccggaattt ccagactgtc gtactggcct
    20281 ttctccacca cgcgggcgta gttgttcagc ccagactgcg tctcttcttt gttgcctttc
    20341 ttcaccgtaa acagcatctc gccgctctca gtgttgtggg ctttgtcgcg ggtcgcgcca
    20401 tattccggca cgccgttgcc gttgtgatcg cggttacgta accaccagtc gtgataggcc
    20461 accagtttcg ggtacatctc tgccaaccag gctttatcct gggtgacgtt gtacacttcc
    20521 atcaccgacc aggcggcaag gctgggtttg gtattacgtt cgttccagtt gccgccatcg
    20581 ccaccacgct cggggctaag gttccacgct atcaggtcgg ggacaaagcc cacatcctgc
    20641 ggacgcacgc tatcgccagg ctggatctgc caggagaaga ccgcgcggat attctctttg
    20701 gcgatgtcgg gattgaaatg cgccatcgca aacgcctgct tccaggtatc ccacggccag
    20761 gtctgattgc cggagaacca gcgcccggtc accgacggtg taacggtgtt aaatttcacc
    20821 gcaccgcccg gtgagcgcca gttaccgttg agcgtttcga tcgctttcac cgcgacgcgc
    20881 gtctgttccg gcgtcgcatc cggattggtt aaccctttct tcaggtattc ttcccagcgt
    20941 tgctgcgagg cggtgagata aaacgccgga cgcgccagaa tatcgcggat ctgcatttgc
    21001 tctttgctaa cttcctgagc ggtcagcaga tgggaatagg tggtgtagag cgtggtcgaa
    21061 ccgttgatat gcgccttact ggtaaagcga ttaccgttga tttcagtctg caccggcagg
    21121 gatttatgca cctgatattc cgattcgccg gaggtcagca gatcccaggt ggcgcgcact
    21181 ttgccaaagg tgactttcag gccatcacgg gtggcgctga ttttgcgctg atagtcaggg
    21241 tattcgccag caatggtttt atcggaaagc ggtttccctt ctttcgcttc cagtttttcc
    21301 agcagttcgc cgtcccacac cagatccagc ggtttattgc tggtgatttt ggtttccagt
    21361 agtgacgtgc gcggcgtggc gaagcgcaga gtcatttcga cttgcacatc ttttgctgtc
    21421 agtttttgca ccagcgcacc gggaatactg tatgcctcca gcgtaaagtc gactttcttg
    21481 ccgtcctgcc agacggtcag gcggtcgaaa ttgctggcca taaagttgat gtactcttcc
    21541 gtcagcagcg caacgcccgg aaagccgccc atggtgttag ggccgtctgg caacagatga
    21601 ccatgccagg ctccgagatc gaaaaacgga ttaaaacgct ggtgatcgtc gtaatcgtaa
    21661 tccttcatgt actgcggcgc gccagtacgg ttaatcacgt ttttataatt gtcggcgtta
    21721 gcggcatggg cggaaaaact tatcagcaga gcgcaggtta ctggcgttaa aatagttttt
    21781 attttcatga aattacagtc cttattacca gtagaaatat tgcatcagga agatttggtc
    21841 gctgggatcg tgagaggcat ttttcatgta gaagcggcta tcaaaagccg tggcgaaacg
    21901 tccgccgccg tattcgtacc agataccaaa ctgcatgaaa gaggtggttt catcgtcagc
    21961 gtggtcaggg cgatgtttgg cgtaggtgta agcggtggag agataaacgc cctttaacgc
    22021 ttcatacatg gcgctcacca tcatcccact ttcacttccc ggtacgtcca gcccgtcggc
    22081 gcgtccggta tggtgccagg cgcgagcggc aaagttagga gttagcaggc ccgtgagata
    22141 gagctgtcct gtgccgtcgg tgatttccag accgttcatc caggtgatgc cttcggcaag
    22201 gtcatactgg atgtaaccgt tcatcattgc cggataggtg tatttgtcgt catagcgatc
    22261 gtacttgcca aaatgtagcc aggctttgct ttcgtcatga tgtccggcag gtgtggcggt
    22321 gacgctataa cgaaagttgc cgcttaagtt ctgcaccttc agcgcggtca taatgtcgcg
    22381 ggtattggga atgacgtagc ccagatcggg ggtgaagtcg ccccaccatt gcaggtcatc
    22441 cagcgaggaa tcctgacgca gactgagcat gatttcggtg ccatcattgg tacgataacc
    22501 gccatagaaa cggttaattc cgccctcgaa accaccccag ctatggtctg gcacccaggc
    22561 attgccgtcg tggtcggcct gcacggtcca gccttcgccg taaatcaggc cgaaccagga
    22621 gccgtacttc atctccaggc caccttcaat ataggtaccg tcgctgtatt tatgtttatt
    22681 ctcaccctct aaatccatat atccaccaac ccctaattcg ccgtaaaaac gaaatgaagg
    22741 agaagatgtc gaggtaattg caggtgtttt tgtgtcgtca tgttctgccg gacgtgcttc
    22801 ttctcctgcc gcagaaaagg cgtagcaaaa cggcagagca agtaatgctc tgcatggtgc
    22861 agtgattaat ttcattgtgt taatccatga gctaaagaaa aagtacagcc ttttatcgtt
    22921 gtaattataa aaatataaag gcagaaacta ttttccccct ccccatccag gaagagggaa
    22981 aatgcctgct cattttttat tagtctgctc aatcaacatt gctggctggc gtcgcttcaa
    23041 tatggcgctc ttcagccgtt aatcccttta tatatttact gtatttccac cacgcaaagc
    23101 cgaggaagat aacaataccg ccgacgttat aaaaaatgat ggtcagaata ttcgcgccag
    23161 tcgggaatgt cgaagcgaca aaccctacgg caaatatcgc aatcagcatt gaaacaacga
    23221 taataccggt gcggcgggag cccatgcgga aatcgcgtgg caggtgatct aatttggcgc
    23281 gtaaattcag gtaagccagc atgatgaata acggcggaag catggacgct gcggcagtca
    23341 tattaataat agtattcatc agatcctgca cggtattgga accgagcatc gggataatca
    23401 tcagcgggat gacgatcagg aactggatcc acgctgcgcg cgctggaacg ccgttttcgt
    23461 tcagttcgac ggttttctta ccaaagatgc cttccgggat ttcggagaag aaaattttca
    23521 ccggcgttgc ggtccacatc agcagggaac cgaacatcgc ggtaaaggac accagaccga
    23581 caaagcgatt catcaacgct tccggtagac caaaatacgc cgccatgccg tggaatacct
    23641 gcaccgatcc gccggtaaat ttcaactctt tgctgctgac gaagacgtta atcagcaccg
    23701 aggagacgga atacagtacg ccgataaaaa tcccggcgag gatgatcact ttaacgaacg
    23761 atttcgaacc gcctttgacg tcgttaacgt acacagcgac ggactccgcg ccacctgcgg
    23821 ccataaagat ccaggtggta acgccgagga acgcccagtt gaagttcggg atcatcgcgt
    23881 caacggtgat ggggtcagca ggctgtacgc cgccaaccag cgccgtacct gccagtaaaa
    23941 tgtaggagag cgttaacagc agcatcagcg ttgaagtgac ggaggtaatt ggccccaaca
    24001 ttttcgcccc gttggtggaa acccaggtgg agaaggcgaa cagcaccata ctgataatgg
    24061 tggtggcaac cggcgtcata atatattcgt agccgaggaa ggcatacgaa gcataagcaa
    24121 taacgcgcgg caacagtgag gtgaaaaaga acaggtttac gaaccagtag gtataggcag
    24181 taataaatgc ccaacgtccg cccagcgaac tttttaccca cgcgtagaca ccggcttctg
    24241 agtttttatt taacgaaaca aattctgcga tgatcagaca gaagggaata aaataaaaaa
    24301 tcgtcgcgag gaaaaacatc ggtgccgagg ccagtccaag ctcaatatta ttattgataa
    24361 cgttgttaaa gctgtaaacg gcggcaaaag tcagcgagag caagccgaat ttgccgattg
    24421 tattacgttt ggtatcagac ataacacatc tccgaaaatg tgtagggtag cggtggcggc
    24481 aaactccttt tgccgccgta gttgttattt gttatggaaa taaccatctt cgatggtgac
    24541 tttgagaacc acttttttga ccgcgttatt gcagataaac cgatacgctt catggatatc
    24601 gcaaataacg atttgccctt cgtggacctc aacggtttct ccgcagcctt ttaaatattc
    24661 acggtcagtt tcatcacgat aatattccac tacctgtaat gtctctttcg gcgcatattc
    24721 aattttttgc tgcccttgca ggtagtaatg cacttcaaaa tagcgtcgat gcccggtaaa
    24781 tagcgcatcg gtcgcggagt ctgtctccac gcggtaagtc aatgagtcac cgatggagtg
    24841 ggcgacgcca ggctgaatgt tgtcgatatt ttcaatcgct tcaacgcagc gttgccactt
    24901 cttgccagag gcgtaaatct ggcggaactg ttctaagtta tcgatgatcc tcattgctta
    24961 ttctcgctgt gcaaattcgt ggaaaagaac cctgcgccga actcatacga cgccaggctt
    25021 tgcgcggtag cttctccgcc agaaaccggc agcaacgtaa agccgtagct gaagtcacgg
    25081 aaccagacgc gccaggagtc cagcacctcg ctgccccagg agttggagcc gaggccaagc
    25141 agctggtggt cgaggttcag ggtgatgtca tcactgcgct gcagctcgtt acagtgctgg
    25201 gcagcgtgga tgttttcctg ggtatagcgc caggcgctga agttaattgg gcgctgcgga
    25261 accaccagca gaccgttgcc gtggcggtta gtcagtgccg tccagcggac atgctgacgg
    25321 ttgccgttgt tctgcgggaa gggatagttc tcgaacatgg catcgacggt gctgcgccag
    25381 atatcgatga tgttagcctg ctggctgtcg gcgtagtttt cgcccggtcc acgaccgtaa
    25441 tacgccacct gatcgtattc gccgttaatc cccatggtga aaccgatgca cggaatgatg
    25501 tgcggatagt cgccgtaacg ctcgccggaa agcgccacgt taacctggcc atcggcagcg
    25561 atgcgccaga tgtaggtgca gcgcatcccg aagtcaaaca ccggcggggc aataactgtg
    25621 cggctgatga tcaacacttc accatcgctc tgttctacgg caaagccgcg cagatgttcc
    25681 tgcatgatct gcaaatgatt cggttgccac agcccttcgt actcctgctt gtggttgtcg
    25741 atcattggct tgaagaagtt gatctttggc tcgcgggtca gcagcgactc gccattcacc
    25801 tgccaggatg tcggtttgcc actcattttt gagaaggtga tcgcgaagtt gtagccgcga
    25861 acggtgcagc tcaaacgatc gtcttccagc gtcagcggac gcgcattatt tggtgcgaaa
    25921 ggcactggtt gcgcggtgtt ttccttcagc gggaactgat aagtggcgat agaatgcccg
    25981 gcttcgctgt agcgggtgcg ggaatctttg gtcaccgtaa tgttgaggaa cgcttcgcgg
    26041 gcgtccagct gcggcagcgt gatctgcaag ggggcttcgc tgttcggcgc aacgtcgcgc
    26101 agtttaatct gctgcgtcgc gagcgtttca ccttcgacgc gcacctctgc gtgcagggtg
    26161 tagtcatcaa gcgtggtaaa ccacagttta ttttcgactt tcagctcgcc gtgagtcaga
    26221 tccagcgcgt ggatttttac cggcgcgata acctgtttgt actctttcag gcccggtccc
    26281 ggcgtctgat cggaatagat caaaccatca agacagaagt tatagttgtt gggatagtcg
    26341 ccgtagtcgc cgccgaattt ataccagacg ttgccgttgt catcctgcgc ctggatcccg
    26401 tggtcgcacc attcccagac ataatgtccc tgaatgcaat cgtgcttata gaagacgttc
    26461 tggtactccg tcagcccgcc tggtccgttc cccatcgcat gagcatattc acagatgatg
    26521 cgcggcttcg gatgcgggta ttcaccaaac tcattcatca gcggcacgcg ggtgtacatg
    26581 gtggaaataa tatcgaccac ttcagcatcg cgatcttctt cgtaatgcac cagtcgcgtg
    26641 tcatccagcg ccttcgctgc gtggtacatc gcgcggatgt tacagccata gccggattca
    26701 ttgcccagcg accagatgat gatcgacgga tggtttttct gcgcgtgaat atggcgaaca
    26761 atgcgctcga cgtagacttt ttcccactgc ggatcgtcgg taatacggct gatatcgccg
    26821 acattagcaa agccgtgcga ttcgacgtcg gtttccgcca tcacaaacag gccgtagata
    26881 tcacacagtt cgtaaaaacg cggatcgttc gggtagtgag cggtacgcac ggagttgata
    26941 ttgtgctgct tcatcaactg gagatctttc tcgacgcgat ccattccaac ggcgcggcct
    27001 ttgcgatgat cgttgtcgtg acggttgacg ccgtgcagca tcacataacg gttattgatc
    27061 cagaacagac cgtcgcgcac tttgatatca cggaagccaa cgcgttgtgg caccacttcc
    27121 agaacgttgc cgttggcgtc tttcagcgtc atgaccagat ggtaaagata aggggattct
    27181 gctgaccatt gctgcggctg ttcgacagta aaagcaaagc tggcgctggt cagtttttca
    27241 attgccaaat gatcaatggc gctgctgtgc accacgcgtt cgccatcaaa cagggtatat
    27301 tccagcgtcg tgacgacagg ggaggcggcg agattttcca gcaccacttc gcaggaaagc
    27361 gtggcatcgc aataggcttc gtcaaagtcg gtacgcacag tgaaatcgtt aatatgcgtt
    27421 aggtgttttc cgaccagata aacatcgcgg aagatccccg ctgaccacca catatcctgg
    27481 tcttccacgt aggtagagtc cgcccactgc atcacgcgca cacacaacag gttgtcgccg
    27541 gttttaacca tcgcgctgat gtcaaactct gcggtcaggc gactgccctt gctgaaaccc
    27601 acatactgac cgttaacata gacttcaaaa taggtttcga cgccgtcaaa tttaatcagc
    27661 gtctgtttac cctgccagcc gtcgctgagg gtgaaaatac gttgataggc accggttggg
    27721 ttatcgctgg ggacaaacgg cacatcgatg gggaacggaa aaccttcgtc ggtatattgc
    27781 agtttgccgt gaccttccat ttgccacatg gcggggacgg taatatgccc ccagtcagcc
    27841 attaactcag aggtgaaggc ttctggtact tgcagcggat ggtcaaaaaa gtggaaattc
    27901 cactgaccgc ttaagggcag aaacaggctg ctggtttcgc gggcaaaggt acgcgcttgc
    27961 gcaacagaat catatgaaaa aaagtacgca cgcggcgcaa gtcggttttc gtgggtgagc
    28021 tgaatgtttt cccagcgatt catagggcct cccggtagag agaaatcgga accattcatg
    28081 gtgatggtag tttgtgtaat tgctggggag tttagtaaaa tttttactaa aaagtagcag
    28141 gtaaatgcat ttactttaac tggatcacga aaataaacgg cagcactgtc cggcaaaaac
    28201 gattgccgga cagtgtgtaa ggggatttaa cgggtcgtgc cgcgcagttt taatttgctg
    28261 ggaacgaaga ctaacagcgg cagcgcgcga ccatcgcggg ctttttcata caccaggtta
    28321 acgccctgac ttcccatcat ctcggaatgg atgcgcacgg tggagagcgg cggaaaggta
    28381 aatcgcgcgg tggggatatc gttaacgctg ataagcgaaa tatcctgtgg gatgttcagg
    28441 cctcgttcat gaattgcccg cagtacgccg atagcaatgg aatcggaagc aacaaacagt
    28501 gccttcggat agtcttcccg cgccagcatt tgttttgcca gttcataacc cgacgaactg
    28561 gaaaaaccgc cgcgccagat atcctcttcg cgtaccactt gtttcagtcg gccatattcc
    28621 gcaaaggcga cctcacgaat atccgccttg ccaggctcat cttcaccgcc aataaaacca
    28681 atacgattaa cgccctggtt gatatagaag tcgatgattt ctttactgat gcgtgccaga
    28741 tcgatatcca ccgcatcgta accgctgccg ggttcgtgaa agtcgataaa acagatattg
    28801 tcggtcaacg cacaggcggc ggcgcgcagg gcgggcgtgg gtttgccgac aattaaaata
    28861 ccggtgacgt ttttaatgtc tggtaatccg ctgtgttcat aacagttggt gagctcaatg
    28921 cccagctttt cgcactgagt ttcaatgccg tggcggatcg ccagatagta aggatcgttg
    28981 atctccagct cctgttggta gctgtagata gccagaatat ggtgttggtt gactgcacct
    29041 gtctggagtt tacgggcact actggtcttg tactccagct tttcggcgat ctcgagaatg
    29101 cgatgtttcg tctcttcttt cacattcaat gtcggatcgt catttaagac cctggatact
    29161 gtcgccaggg atacgccagc ttcgattgcg atgtctttta gtgttgccat gtttaccttt
    29221 tttactttcc ctgatgtgcg cccccattgt agaggaagtg cttatcgggt cacctgtttt
    29281 cagtaaataa agcgcgtttc tttgacgctg taacggtaac acagcggctc acgaatgtga
    29341 tcacgcctgc attctccatt tttagcctac aggattgaga aaaacttttg ctatagttta
    29401 gtaaaatttt acccgaaggg aggaaacaat ggaaaccgtg gcttacgctg attttgcacg
    29461 tctggaaatg cgcgtcggaa agattgtgga agtgaaacgc catgaaaacg ccgacaagct
    29521 gtacatcgta caggttgatg tgggggaaaa aacactgcaa accgtgacca gcctggtgcc
    29581 gtactacagc gaagaagagc tgatggggaa aacggtggtg gtcttatgca atctgcaaaa
    29641 agcgaaaatg cgtggtgaaa cgtcggaatg catgctgttg tgtgcggaaa ccgatgacgg
    29701 cagtgaaagc gtgttgttaa cgccggagcg gatgatgcct gcgggcgtac gcgtcgtata
    29761 aaaagatcgg atggcgacgt cgtatcgcca tccgatttga tattacgctt cttcgacact
    29821 tactcgcatg gccgccagcg ccttacgcgc cgctttgatc accagttcac actgttcaat
    29881 ggtcagtgtc agtggcggtt caatgcggat cgttttggcg ttattgagcg ttccggccac
    29941 cagtacgcgc tggcggaaca tctcgctggc aaagttatag ccgatttcgt tatcaacaaa
    30001 ctcaattgcc atcaacatcc ctttaccacg cgcttcctgt accagatcgg gatattcccg
    30061 cgccagttga cggaaaccgt ccagcaacat atcgcctttt tgctcagcct gagccggtaa
    30121 gttctgctcc agcaacacat tgatggtcgc cagcgccgcc gcacaggcca gcgggttgcc
    30181 gccaaaggtg gtggtatgca ggaatgggtt gtcgaacaga actgaaaaca cctcttcagt
    30241 ggcgatggtc gcgccaatcg gcatcacgcc gccgccgagc gctttggcaa ggcagaggat
    30301 atccggctgt acgttctcat gctcgcaggc gaacatcttg cccgtgcgcc ccatgcccgt
    30361 ttgtacttca tcgaggatca tcagtgcgcc gaactcatcg catagcttac gtacggcggt
    30421 gagatagccc ggcggcggca gaattacgcc accttcaccc tgaatcggtt cgaggatcac
    30481 cgcagccaca tcatcaccgg tttttttgca ctcgttaaga gccgtgcgca tggcttcgat
    30541 attgccaaac ggcacatgac ggaagcccgg cagcagtggc ataaacggtt tgcggaaggt
    30601 cgatttcgcc gtggccgaca gcgcgccaag tgatttaccg tggaacgcgc cgctggtggc
    30661 aataaaagta aacttgccgc gcggtgactg gtaagctttc gccagcttca gcgctgcttc
    30721 aacggactcg gtgccgctat tacagaagaa gctgtatttc agtttaccgg gcgttagcgc
    30781 agcaagggtt ttcgccaaca tcgcccgtaa cggatcgagc agctcctggc tgtgcagcgg
    30841 ttgtttcgca agttgattct gtacggcgga aaccacaact ggattacggt gccccacgtt
    30901 gaaaattcca aaacctccca ggcagtcgat aaactcctgt ccctgggtgt cgacaagcgt
    30961 atttaaacct cccgcttgcc actctacggc tccgtaatcc ccgccggcgg taacagattt
    31021 gcgatactct aaaaaccccg gattgacatg ctctttgaag tattcaatca cctctcggtt
    31081 aagtgctttc atctcctcat gatccagcgt tcgcttctca atgagattca gggcgtgggc
    31141 gctgcacgct aaagccgatg cgctcgaagg taacctgttc aaaatatgct ccggaggctc
    31201 gcgtatcaca tgataccgat ttaagtattg cagggattgc gccactccgg ctgcgatcgc
    31261 gaaaatcggg ataaacacaa attcggttat catttgtgca atatttaatg ctatctgtta
    31321 acatttgttg ttattttgca cggtttttgt cgggtatgga tttgatgatt gctgcgcaaa
    31381 tgcacgtttt cagggcaata attgcctgat ttttgggcaa gataattaac gttttcgtat
    31441 agtaacagag tgaaagtatt ttaaatcaaa gaattagatt tgtgctttaa tcgcaaattg
    31501 cgatctaaat caaattaatc ggttaaagat aaccgcagcg gggccgacat aaactctgac
    31561 aagaagttaa caaccatata acctgcacag gacgcgaaca tgtcttctca tccgtatgtc
    31621 acccagcaaa ataccccgct ggcggacgat accactctga tgtccactac cgatctgcaa
    31681 agctatatca ctcatgctaa tgacactttt gtgcaggtga gcggctttac cttgcaagag
    31741 ttacaagggc agccgcacaa catggtgcgt cacccggata tgccaaaagc ggcgtttgcg
    31801 gatatgtggt tcaccctgaa aaaaggggag ccctggagcg gcatcgtgaa aaatcgccgc
    31861 aaaaatggtg accattattg ggtgcgggcc aatgcggtac cgatggtgcg cgagggaaaa
    31921 atcagtggct atatgtcgat tcgtacccgg gcgacggatg aagagattgc ggcggtggag
    31981 ccgctgtaca aagcgctgaa cgccggacgt accagtaagc gtattcataa aggcctggtg
    32041 gtgcgtaaag gctggctggg taaactgcct tcattaccgc ttcgctggcg ggcgcgtgga
    32101 gtgatgaccc tgatgtttat cttgctggcg gccatgcttt ggtttgttgc tgccccggtg
    32161 gtgacgtatt tcctctgtgt gttagtggta ttgttggcaa gcgcttgttt tgaatggcag
    32221 attgtgcgcc cgatagaaaa tgtcgcccgt caggcactga aggtggcgac cggagagcgt
    32281 aatagtgttg agcacctgaa tcgcagcgat gagctggggc tgacattacg cgcggtaggg
    32341 cagcttggcc tgatgtgccg ttggctaatt aacgatgtct caagccaggt gtccagtgtc
    32401 agaaatagca gtgagacgct ggcgaaaggc accgatgaac tgaacgaaca tacccagcag
    32461 acagttgata acgttcagca aacggtggcg accatgaacc aaatggcggc gtcggtgaaa
    32521 cagaactctg ccacggcgtc ggctgccgat aaactttcta tcaccgccag taatgcggca
    32581 gtgcagggtg gggaggcgat gaccacggtg atcaagacaa tggacgatat cgccgacagt
    32641 acccagcgca ttggcaccat tacttcgctg attaacgata ttgcgtttca gaccaatatt
    32701 ctggccctga atgcggcggt ggaagcggcg cgtgccggcg aacagggcaa aggttttgca
    32761 gtggtggcag gggaagtgcg tcatttagcc agccgcagcg ctaatgctgc caacgatatt
    32821 cgcaagctga ttgatgccag tgctgataag gtgcaatccg gttcgcagca ggtacacgcc
    32881 gccggacgga cgatggaaga tattgtggca caggtgaaaa acgtcaccca gttgatcgcc
    32941 cagattagcc attcaacgct ggaacaggcc gatgggcttt ccagcctgac ccgtgcagtg
    33001 gatgagctta acctgatcac ccagaaaaat gccgagctgg tggaagagag tgcgcaggtg
    33061 tcggcgatgg tgaaacaccg cgccagccga ctggaagacg cggtgacggt gctgcattaa
    33121 tcggtatgcc ggatccggcg gttggagcac aatgcctgat gcgatgctgg cgcatcttat
    33181 caggcctgcg gggtgtgtag cgggtgtagg ccggataagg cgcgtcaagc gtcgcatccg
    33241 gcaattgcac cgcgccactg gcgggtgcgg cgattaatcc agttgcgtaa tatcaaaagc
    33301 ggcgcggtcg atcaccgcaa tgatcttttt tatttgtgca tcactgatat cgctctggtt
    33361 gacgtgtaaa tccagcaccg ctttaaaatt atccagcgcc cgcttcattt gcgggttctg
    33421 gcgcagcgcc gcgccaacgc aacgcgcttt gatgcgttct tcaatcatct ccacctgttc
    33481 gcggttttct tccagccact gagcgccttg ttcggtcagc gcaatctgct tcttaccacc
    33541 ttcctcttcg cggatggtaa tcagcgactg ctcctgcaga aaatccagcg ttgggtagat
    33601 gacgcccggg cttggggtgt aattcccctg ggttaggttc tcaatcgctt taatcaattc
    33661 gtaaccgtgg ctgtcatcgc gcgagagaat atccagaatc accagacgca attcaccgtg
    33721 accaaagaaa cgttgccgac gaccgccgcc gcgaccgtgg cgaccaccgc agcattgacc
    33781 gtgttcatgc tggtgaccgt gtccgcagtg ctcgtgttct gacttctcac ctttgcagca
    33841 gccctcatgg cgtggctggc cttcatgttt acaacaccct tcgtgatgat ggctcatatc
    33901 agcctccttt tgcttgatta gatatatcta atttatatct gatgtgagca ttactgcaag
    33961 tacaaaaatg atgtttaaac gtggaagcac ctcacatcca ggccggataa gacgttcacg
    34021 ccgcatccgg cagcattgct atggcactga atgccttcac atacttcaga tatatcagtt
    34081 ctacaaatcg cttgcattta tcatgattaa caatcattat catttacgaa aattatttag
    34141 atatatctga ttactatcac gaaggcgata acaatgaata actccccccg ctacccgcag
    34201 cgcgttcgca atgatctgcg cttccgtgaa ctgactgtgt tacgcgttga gcgcatcagc
    34261 gccggttttc agcgcattgt cctcggcggc gaggcgctgg acggttttac atcgcgcggc
    34321 tttgacgatc acagcaaact cttctttcct caacctgacg ctcactttgt gccgccaacg
    34381 gtaacggaag agggcatcgt ctggccggaa ggaccacgcc caccgtcgcg tgactatacg
    34441 ccgctgtatg acgaactacg ccatgaactg gcgatcgatt tctttattca cgacggtggg
    34501 gtcgccagcg gctgggcgat gcaggcgcaa ccgggcgata aacttacggt ggcaggtccg
    34561 cgcggttcgc tggtggtgcc ggaagattac gcgtatcagc tgtatgtctg cgatgaatcc
    34621 ggaatgcccg cactgcgccg ccgcctggaa acgttgagca aacttgccgt taaaccgcaa
    34681 gttagtgcgc tggttagcgt gcgggataac gcctgtcagg attatctcgc gcaccttgat
    34741 ggttttaata tcgaatggct ggcacatgat gagcaggcgg tagatgcgcg tctggcgcag
    34801 atgcaaatcc ctgccgatga ttacttcatc tggataaccg gcgaaggtaa agtcgttaag
    34861 aatttaagcc gccgctttga agcggaacag tatgacccac agcgggtacg tgcagcggct
    34921 tactggcacg caaagtaact gatatataaa aagaaaaagg ctgacgattt ctcgtcagcc
    34981 tttgctatat ctggtggccc ctgctggact tgaaccagcg accaagcgat tatgagtcgc
    35041 ctgctctaac cactgagcta aggggccatg gtagcggatt ataaagtaac tccgtgtcgc
    35101 aatccagcca ttaccgtgcg cctgctgttt ttataaacaa tgtattttca atccgttata
    35161 cttttcctgg tgatgttaga aaggagtaaa tatggttgag gatattttgg ctccagggtt
    35221 acgggtcgtg ttttgcggta tcaaccctgg gctttcatcc gctgggactg gttttccctt
    35281 tgctcatcca gcaaatcgct tctggaaggt gatatatcag gccgggttta ccgaccgtca
    35341 gttgaagccg caggaggcac agcatctgct ggattatcgt tgtggcgtca ccaaactggt
    35401 agaccgtcca acggtgcaag ccaatgaagt ttcaaagcag gagctgcacg caggtgggcg
    35461 taagctgatt gaaaaaattg aagattatca gccgcaggcg ttggcgattc tgggcaaaca
    35521 agcatatgaa cagggattca gccagcgcgg tgcacagtgg gggaaacaaa cgctcaccat
    35581 tggttcgacg cagatttggg tgctgccaaa tcccagcggt ttaagtcgcg tttcactaga
    35641 gaaactggtt gaagcgtatc gcgagctgga ccaggcgctg gtagtgcgtg ggcgataaaa
    35701 aacgccaccg aaaaggtggc gtttgtgcaa agggactagt gccgggtgcg gcgtaacgcc
    35761 tgatccggcc taccgattaa tcgtccagga agctacgcaa cacttcagaa cggctcgggt
    35821 gacgcagttt gcgcagcgcc ttcgcttcga tctgacggat acgttcgcgg gtaacgtcga
    35881 actgtttacc cacttcttcc agcgtgtggt cggtgttcat atcgataccg aaacgcatac
    35941 gcagaacttt cgcttcacgc gcggtcaggc cagccagcac gtcgtgcgtt gccgcacgca
    36001 ggctttcggt ggtcgcagaa tccagcggca gctcgagggt ggtatcctcg atgaaatccc
    36061 ccagatgcga atcttcatca tcaccgatcg gcgtttccat ggagattggc tctttggcga
    36121 tcttcagcac tttgcggatc ttgtcttccg gcatcagcat acgttcagcc agttcttccg
    36181 gcgtcggttc acggcccatc tcttgcagca tctggcgaga aatacggttg agtttgttga
    36241 tagtctcaat catatgcacc ggaatacgga tggtgcgcgc ctgatccgcg atagaacggg
    36301 tgatcgcctg acggatccac caggttgcgt aggtggagaa cttgtaacca cggcggtatt
    36361 cgaatttatc aaccgctttc atcagaccga tgttgccttc ctgaatcagg tcaaggaact
    36421 gcaagccacg gttggtgtat ttcttggcga tagaaataac cagacgtaag ttcgcttcaa
    36481 ccatctcttt cttcgcacgg cgggctttcg cttcaccgat ggacatacga cggttgatat
    36541 ctttaacctg ctcgatggtc aggccggttt cttcttcaat ctgctgcagt ttctgcaggg
    36601 cgcgatgcac ttcttcagag acatcgtgca gtttttccga ccacggcttg ttcatcgcaa
    36661 ttgccgcgtt gaaccaggta tcgctggttt cgttgccggt aaacagggta atgaagtttt
    36721 tcttcggcat tttgcactgc tcaacgcaga gcttcatgat cagacgttct tgcgtacgaa
    36781 cgcggtccat catgacgcgc atgctgttga ccaggtagtc aaactgcttc ggcaccaggc
    36841 ggaactgttt gaatacttca gacagtttca ggatctcttc ctgagcggca gcgtgactgc
    36901 gacctttcgc tttgatggtg tcacgcgtta caacgtactg agcgcgtagt tccgcaaatt
    36961 tttcgcgagc cagttccggg tcgatgctgt tgtcatcatc ggcgctgtcg tcatcgccat
    37021 cttcttcgtc ttcatcttcg tcatcgtcca gatcttcctg ggaaagctca gaaccgacgt
    37081 gagtggcggt aggtgccaga tcttcttctg cgttcgggtc aacaaagccg gtgatcagat
    37141 cggacagacg cgcttcttct gcttcaacac gatcgtactg ttccagcaga taggtgatcg
    37201 cttccggata ttcagcaacg gagcattgaa cctggttgat cccgtcttca atacgcttag
    37261 cgatgtcaat ttcgccttcg cgggtcaaca gttcaacggt gcccatttca cgcatgtaca
    37321 tgcgtaccgg gtcagtcgtg cgcccgattt cagattccac gctggaaagc acctgcgcgg
    37381 cggcttcggc agcatcttcg tccgcggtgt tttcagccag catcagatca tcggcatccg
    37441 gtgcttcttc catcacctga atgcccatgt cgttgatcat ttggatgatg tcttcgatct
    37501 gatctgaatc gacgatatct tccggcagat ggtcattgac ctcggcatag gtcagatagc
    37561 cttgctcctt accacgggtg acaagaagtt tcagctgtga ctgcgggttt tgctccataa
    37621 gacggtatcc acacttattt catgaggttg gtgttgggcg attgacccga tgtccttcag
    37681 ccgttaacgc tgaaatccaa cggttgttta ccgccaacga taattacgag ggcgtactta
    37741 tatatttgcc gctgcctctc agtgcggctg tcgggggctt cccgatcgct cttcggcact
    37801 taagccgtta aatcactttt tcgccagctc ctggtttaat gtccagagct ccaggcgttc
    37861 ttcgttgctt aaaccatgcg tgcgctcacg agcgattaac tcttcctggc gcagttcaag
    37921 cagcgaatca aacatatggt tgagtgagtc ggtgaaggtt tgctcagcaa tattcttatc
    37981 tgctatatcg tcccacatcg acagtttttc aagggtggca gcattatttg taccacgata
    38041 gtgctctaaa agttgcccgg tggtcagacc tggctgggag agacaagtgt tgaccagttc
    38101 tctgaataag ccaagtccag ggagcttatt ttcatccaga ttctcaagcg gcgggaccaa
    38161 cgtcgctaat tctggatttt gcaccagcaa ccctataagt atacgcatgg tcgtgcgttt
    38221 tagctgcgga acagggcgag aaacgccgct ctctgccgct tttggcatta atcgttcaag
    38281 ctggctgtca tcaagtatgc ctaatttgtt gcctaattcc tgacgaagat atattcgcag
    38341 cgtttcgccc ggcacttgcg atatcaatgg cagtgccagc gtactcaaac gtgcgcgccc
    38401 gtcaggggta ctcagatcaa cttgcggcat caggctgtta aacagaaatg cggaaagcgg
    38461 catcgcctgc tccatccgcg cttcaaacgc ttctttacct tcttttcgta ccagcgtgtc
    38521 agggtcttcg ccatccggca aaaacataaa gcgtagctga cggccgtctg tcatgtaagg
    38581 cagcgccgtt tccagcgctc gccatgcggc atcgcggcct gcacggtcgc cgtcataaca
    38641 gcaaatgaca ttgttggtcg cgcggaacaa cagttgtatg tgatcggcgg tggttgacgt
    38701 acctaacgac gcaacggcgt aattaatgcc gtattgcgcc agcgccacca cgtccatata
    38761 gccttcgacc acaagcagac gattgggttc agcgttatcc tgctgcgctt cataaagacc
    38821 gtaaagctgg cggcctttat ggaaaatgtc tgtttccggc gagttcaggt atttgggggt
    38881 atcgttgccc agcacgcgcc cgccaaaacc aatcacccga ccgcgtttat cgcgaatggg
    38941 gaacatcacc cgctcgcgga aacgatcgta actgcgtccc tgatcgttag tgaccaacat
    39001 ccccgcatca atcaatgact ggcgattttc tggattgccg ccaaaccgct tcaggacgtt
    39061 gtcccagccg gggggcgcaa aaccaatcgc aaagcgagcg ataacctcgt ggcttaatcc
    39121 gcgtttttcc agatactggc gcgcagacgt ggcaacaggt tgttgtaaag attgttggta
    39181 aaacgtattc agaccgtcca tcaactgata aagcgtttgc ctctgatggc gctcgatctg
    39241 gctggggccg ctgcctgctt caaatggcac ttcaagattg tgcattgctg ccagctcttc
    39301 gaccgtttca acgaactcga gcttgtcgta gttcatcagg aagtcgatcg cgttgccgtg
    39361 cgcgccacat ccaaagcagt ggtaaaactg tttctcaccg ttaacggtga atgacggggt
    39421 tttctcgttg tggaatggac aacacgcgtg gaaattcttg ccctgctttt tcagcttcac
    39481 acgggcatcg atcagatcga cgatgtcagt gcgtgccagc agatcattaa tgaatacgcg
    39541 tgggattcgt ccagccatag gccccgattt ttagcaattc ataaacgaaa ataagccgcg
    39601 cattcctttc ggaagcacgg ccttacaact acaactcggt ctgatcggag agcaacgctc
    39661 tcggggaatt agtacagacg agtgcggcgt gcgttttcgc gagccagttt cttcgcgtga
    39721 cgtttcactg cagaagcttt agcgcgctta cgttcggtag tcggtttttc atagaactca
    39781 cgacgacgaa cttccgccag aacacctgct ttttcgcagg aacgcttgaa gcgacgcaga
    39841 gctacgtcga acggctcgtt ttcacgtact ttaattaccg gcatgtgcct ctcacctttg
    39901 attaattcgg tttgccgctg gcatcaacgc cagcttattt caaaatggtg cggaatttta
    39961 ctgcaattgc tgctgctttg taaagcaccg cggccttttt tgaaagggac ttttataagg
    40021 gtgaggagta tacacgaggc tttctccagg ggcgaacaaa gttttacatc aacccgcatt
    40081 ggtcctacac tgcgcggtaa taaagcgagg taaaacaagt catgcgtgta ctgggtattg
    40141 aaacttcctg cgatgaaacc ggcatcgcca tttacgacga tgaaaaaggt ttgttagcca
    40201 accaattgta tagtcaggtg aaattgcacg ctgactacgg cggcgtcgtg cctgaactgg
    40261 cctcccgcga tcacgtgcgc aaaaccgtac cgttgatcca ggcggcgcta aaggagtctg
    40321 gtttaacggc aaaagacatt gatgctgtgg cctataccgc aggccctgga ttagtcggcg
    40381 cactgctggt tggcgcaacc gtggggcgtt ctctggcgtt tgcctggaac gttccggcaa
    40441 tcccggtaca ccatatggaa gggcatctgt tagcgccgat gctggaagat aacccgccgg
    40501 aatttccgtt tgtcgcgctg ctggtgtccg gcggtcatac gcagttaatc agcgtgactg
    40561 gcattggtca gtacgagctg ctcggcgagt ctatcgatga tgccgccggt gaagcgtttg
    40621 ataaaaccgc gaagctgctg gggctggatt atcctggcgg accgttactg tcgaaaatgg
    40681 cggctcaggg tactgccggg cgctttgttt tcccgcgtcc gatgaccgac cgtccggggc
    40741 tggatttcag cttttctggt ctgaaaacct ttgcggcgaa cacgattcgt gacaacggca
    40801 ccgacgacca gacgcgtgct gatatcgccc gcgcctttga agatgcggtg gtcgatacgt
    40861 tgatgattaa gtgtaagcga gcgttggatc agacgggctt taagcgactg gtcatggcgg
    40921 gcggcgtgag tgctaaccgc acgttacggg cgaagctggc ggaaatgatg aaaaaacgcc
    40981 gcggcgaagt gttctacgcg cgtccggaat tttgtactga taacggcgcg atgatcgcct
    41041 atgccggaat ggtgcggttt aaagcaggcg cgacggcgga tctcggcgtt agcgtgcgtc
    41101 cgcgctggcc actggcagag ttaccggctg cgtaaaacta tccggtgccg gagagcaatt
    41161 tccggcaccg tcctcactta aagcaacacc acgggcatcc acagcaagcc ggtaatcacc
    41221 agcaacacga ggaatatcag tccaaaaatc gcccccagtc gccagtaatc caccgttggc
    41281 agataaccac taccgtagta aatcggactg ggtccggtgg cgtatggtgt aagaatgctc
    41341 cccagaccaa ttgccgcgcc aaccatcagg cagaacaccg gcagcgggat ttccggcatc
    41401 gccagcgcag cggcaatcat catcggtgcg agggcggagg tatacgccgt ggcgctggcg
    41461 aaaaagtagc gcagcagata aaacaccaca atcaacgcca ccatcaccat cgttggcgaa
    41521 taaccgctta agctgcctgc taacagtttg ccaaaccagc taataaaacc agtgttgttg
    41581 agtccggtag cgagggtgat aagcgaggcc agccagaaga aaacgttcca cgcggcttta
    41641 ttactgacaa tgtcgtccca actgataatg cgcagaagca gcatcagtgc caccacgctg
    41701 taaccgacca tcgcggcatc gatataatca ccgccgaaaa tccacagcac cagcgcgcct
    41761 accatcagcc ccagcatccg tttttcacgc gaacagagcg ggcccattgc ctgcagttcc
    41821 gtctctgccc agcgcggcac ctgatcgcct gacttcagta ccggcgggta cagcacataa
    41881 gccagccagg gaaccagcag caccagcaaa atactgagcg gcaacatccc gaggaaccag
    41941 tcgccccaac tcagcgtggc gtgagatgcg cttttcatca gtccaattaa cagcaagttt
    42001 ggtgccatcg ccgtcaagaa aatggcgctg gtcacgcagt cggcaacaat ccccatccac
    42061 atgatgtacg agccaatgct gcgcgaactg ctgtcgtttg gttgtgattg atagagcggt
    42121 ggcaggttac ggatgatggg atagataatc cccgcaccac gcgccgagtt ggacggtgtt
    42181 acaggtgcga ggatcagctc ggagaacatc accgcatagc cgagaaacag cgtgcgatgt
    42241 cccatctttt tcaccagaat cagcgcaatg cggcgtccca gcccggtttt ttcatagcct
    42301 gtgccaaaca taaaggcggc gaaaatcagc cagataaccg aattagaaaa accggaaacc
    42361 gcccacgaga gggattttgc agtgaattta aagcctggct gggcgagctg ttcggggctg
    42421 aacagcagcc agggagagag tatggcgatg atggagatac ccaccatcgc caccacggca
    42481 cccggcacgg gttcgaggat cagtccaacg atcacgccag taaaaacggc aaagtagagc
    42541 caggtatgac tctccagccc tgcgggaacc ggaattagag caataatggc gatgaccgcc
    42601 agcggcgcaa ggtatcgcca ccattcagtg gaaggtttca tcgtgttatg cctgcgaaaa
    42661 aggagagggg gcgagcctct ccgggagggt tatttgatgt aatggacgtg ctcgcagatc
    42721 tcttccacga tgggatcgcg gcgttcggcg aacagctttt tgttttcggc tatcaggttg
    42781 ttgccgtggg tatcaataga gacaatcagc gggccgaact ctttgacccg gcagacccac
    42841 agtgactccg gcatcccgag ttctgtccag tgcacttctt caatctcttc cacctgggtt
    42901 gccgccagca ccgcgcagcc tgccgggaaa atcacatgta gcgccttgaa tttctggcag
    42961 ccttcttcgg tcagcggccc cattccgcct ttgccaacca ccagtttcac gccggtctgc
    43021 tcgataaatt cacgttcaaa actttccata cgcatactgg ttgtcgggcc aacggaaacc
    43081 atctcccatt tatcgccgtt tttgcgcacg atggggccag cgtggaaaat cgctttgccg
    43141 ttgagatcgt aagggatcgg acgtttcagt tcgatcaagc ggcggtgaca aacgtcacgg
    43201 caggtcacca gcgtaccggt caggtagatc acatcgccga cgcgaatatc ttgcagatct
    43261 tcagctttga tcggggttgt caggatcttt ttcataacgc gctccgggtg tgagacagat
    43321 tttcaaaggt gagatcggca tgaaccagca gtgtgccgcg acgatgcgcc cagcagccgg
    43381 tagagacagc aacgccgatg gttgacggat ggcgggcggc agattcgata tgcacgccca
    43441 tcactgaact gttgccggtc agcccttgtg gaccaatccc cagacggttg agtccttctt
    43501 ccaggcgtag ctccagctct gccgcttttg gattgggatg gcggctgcca atcggacgca
    43561 aaatggcttt acgcgagagt acggcggcgg tttccaccga ggtggcgatg cccacgccca
    43621 ccagtaccgg tggacaggcg tttacggcga gggtggagat attttcgaag acgaatttca
    43681 ccacgccttc gtagccttct gacggcatta acactttcga gcggccaggt agcgtgcagc
    43741 cgccgcctgc catgtaaact tcgatttctg catcgtcatt gtcggggatg atgtcccagg
    43801 tgacccacgg tacgccgcta ccggtatttt tgccggtgtt tacttcgtca aaaatttcta
    43861 ccgcattgtg acgtagtggc gctttgacgg ttgcctcttc cacggcttgt ttgagtatgc
    43921 tttgcagctc gccaagcagt gggaagcggg aaccgacttt aacgaagaac ataatctccc
    43981 cggtgtcctg acaggcagga cgattcaggt caatcgcttt ttgcatgttg tcgaacatcg
    44041 tatggtagat aattttcccc atcgacgacg tttcggcatc ctttagctgt tttagtttat
    44101 ccaccacgtc atcaggcatt cgggtagaaa tcatggcggt aaagttagcg acaatctctg
    44161 tcaacttatt cactgcctgt tgcttattac tttcgctcat catggcaact ccagtttttg
    44221 tatttgtctg gaaaaattca ccgccacaaa ctaccactaa aaatgtggtt ttatattttt
    44281 tgccaccgtg aatatgtaat taacagttcg tgaatcaacg cgaaaataag aatgaatatt
    44341 gcgccagagc agggaatggc aatgttttgc gaaatacact gcgcttatca caactgcgga
    44401 taattaacga tgctgaatag ctggccttta gccaaagact tgcaggtact ggtagaaatc
    44461 gtccacagcg ggagttttag cgccgcagcg gcgacgcttg ggcagacgcc tgcatttgtc
    44521 accaagcgga tccaaatcct tgaaaatacg ctggcaacaa cgctgctgaa ccgctccgct
    44581 cgcggcgtgg cgctgactga aagtggccaa cgttgttacg aacatgcgct ggaaatcctc
    44641 acccaatatc agcgactggt cgatgacgtc acgcaaatca aaacgcgccc ggaggggatg
    44701 attcgtattg gctgtagttt tggttttggg cgcagccata ttgcgccagc cattaccgaa
    44761 cttatgcgca attatcctga gttacaggtg cattttgaat tgttcgatcg gcaaattgat
    44821 ttagtgcagg ataatattga tctggatatt cgtattaatg acgaaattcc tgattattat
    44881 attgcgcatc tgttaacgaa aaataaaaga atattatgcg cagcacctga gtatctgcaa
    44941 aaatatccgc agccacaatc attacaggaa ttaagtcgtc atgactgtct ggtgaccaaa
    45001 gagcgcgata tgacccacgg aatatgggag ttggggaacg gtcaggagaa aaaatcggtg
    45061 aaggttagcg ggcatctttc ctccaatagc ggcgagatag tgttgcaatg ggcgctggag
    45121 ggcaaaggga ttatgctgcg ttccgagtgg gatgtgttgc cgtttctgga gagtggcaaa
    45181 ctggtgcaag tattgccgga gtatgcacaa agcgccaata tctgggctgt ttaccgggag
    45241 ccgctctatc gcagcatgaa attacgtgtc tgcgtggaat ttctggcggc atggtgccag
    45301 caacggctgg gcaagcccga tgaaggctat caggtcatgt agatccacca gaaatcactc
    45361 gggatccttt tcgcgctttc ttttgaattt cgtccagatt tttgtctcct gacgacgcca
    45421 cagacgctgg atgttgtcat gatgacgcag caggatcagg caagagagca tcgaaaccgg
    45481 gaaggtgaat tgtggcttaa accaccatac ataaaacgga gcaatcagtg cactgacaat
    45541 cgctcccagc gacgagtatc cgctcaatag cacggtcagt aaccaggttc ccgccattac
    45601 tccggtgaga tcccagccaa tgggtgcgat ggcaccaaaa gcggtagcaa cgccttttcc
    45661 tcctttaaat ccgaagaaaa cgggccagat gtgtccaaga caggcggcga tggcaattaa
    45721 gcctagccag aaggggctga cacctaattc atacgcgccc cagacgggca acattccttt
    45781 cagaacgtcg aaaatcagta ctgctacggc tgctcccttg ccaccgatac gtaacacatt
    45841 ggttgcgcct ggattgccgg agccgctggt tcgcggatcg ggcagcccac acaagcggca
    45901 aaccagaatg gcactggaaa tggagccgca gaggtacgcg atgaggatca ttccaggcgc
    45961 gattgcactc ataagctgtt ccgttttgaa aattcgtgtt caacgatgaa tctgtggata
    46021 atacgcacat ttcgccggaa gtggtatccg gttagccaaa aagcaggcag gacgtgatgg
    46081 atattgtatt tatagagcaa ctttcggtaa tcaccactat tggtgtttac gactgggaac
    46141 agaccatcga acagaagtta gtgttcgata tcgaaatggc atgggataac cgtaaagcgg
    46201 cgaaaagtga tgatgtggcg gattgcctca gttacgctga cattgcagaa acggtggtca
    46261 gccacgtcga gggggcgcgt tttgcgctgg tggaacgcgt ggctgaagag gtggcggagc
    46321 tgctgttagc acgcttcaac tcgccgtggg tgcgtatcaa actcagcaag ccaggcgcag
    46381 tggcgcgggc ggcgaatgtt ggcgtaatca ttgagcgtgg caataatctg aaagaaaata
    46441 attaatttta cagctgttaa accaaacggt tataacctgg tcttactgca gtagtccgga
    46501 caagcggtac attttaataa tttaggggtt tattgatgag cgatatgcac tcgctgctga
    46561 tagcggcaat attgggtgtg gtcgaaggat tgacagaatt tctgccggta tccagcacgg
    46621 gccatatgat tattgtcggt cacttgttgg ggttcgaggg cgacacggcg aaaacctttg
    46681 aagttgtgat ccagttagga tcaattctgg cggtagtagt gatgttctgg cggcgtctgt
    46741 ttggcctgat tggcatccac tttggccgcc cgttgcagca cgaaggagaa agcaaaggtc
    46801 gtttaacgct gatccacatt ttgctgggga tgattccggc ggtggtactg gggctgttgt
    46861 tccacgacac gattaagtca ttgtttaacc cgataaatgt gatgtatgca ctggtcgttg
    46921 gcggtttgtt gctgattgcc gccgaatgcc tgaagccgaa agagccgcgt gcgccgggtc
    46981 ttgatgatat gacctatcgt caggcgttta tgattggctg tttccagtgt ctggcgctgt
    47041 ggccgggttt ctcccgttcc ggggccacca tttcaggtgg gatgctgatg ggcgtgagcc
    47101 gttacgctgc ttccgagttc tcgttcctgc tggcggtacc gatgatgatg ggcgcaacgg
    47161 cgctcgatct ctacaaaagc tggggcttcc tgacaaccgg cgatatcccg atgtttgccg
    47221 ttgggtttat caccgctttt gtggtggcgc tgatagcgat taaaaccttc ctgcaattga
    47281 ttaagcgcat ttcgtttatc ccgttcgcca tttatcgctt tattgtggcg gctgcggtgt
    47341 acgtcgtgtt cttttgattg agaaaaggtt cgggagcagg cctggttttc tccctcgctc
    47401 tgtagggaga gggccggggt gggggtgatt gttcgcaccg gtgctggtct gttcccctca
    47461 ccctaaccct ctccccgaag gggcgagggg atggttcgtg ttaacgttta gttttatact
    47521 cagtcaggct ttgggcaacg ttgttccttc caactggcta ccgccgcaat ccgccgtcgg
    47581 gtcagctcct cgcgaatctc cacaccttta aatcccgctt caacgaccgc ttttgtcggc
    47641 actgactgcg ccacttccca ggcttcgcgc aaccaacggc cttgcgggta gtccgctgat
    47701 tcaaaaccgg ttctgccgcg tacgtcagcc tcgctggtca gcgccagttg ctcgacacgc
    47761 tgcggtttac gccaggcatc gatggaatca aataatttga cgatggtttt tgggttcagc
    47821 attgggaagg tgtggatgag atcgtgaaac tcagccacca gtctggctaa atcgcgaatt
    47881 tcatttggca cgcgcagacg ctggcatagt tgttccacta acttaacacc cgccgggcca
    47941 tgcccatgat gacgcggcca aagttctggc ggcgtcagtc ctttaccgag atcgtggcat
    48001 aaagttgcga aacggacatc aacctgcgga ctcagcatcg ccgccattga gagcgtcatt
    48061 aaggtatgaa tacccgtgtc gatttccgga tgccacctgg caggggccgg aacgccaaac
    48121 agggcgtcaa tttccgggaa taaaacgcga agtgcaccgc aatcgcgcag tacctggaag
    48181 aacacctggg gattgcgggt ggtgagggcg ctttccgtct ctttccatac ccgttcaggc
    48241 gtcaggtgtt ccagttcacc cgcatgggtc atctcgcgca tcagcgtcag agtttcatcg
    48301 gcaatacgaa aaccgaggtg ggcataacgc gcagcaaaac gcgccacgcg cagaacgcgt
    48361 aacggatctt cgccaaaagc gggggaaaca tggcgcaaca gacgattttg cagatcgccc
    48421 agaccgttgt acgggtcgat aatctcgccg ttatcgtcct gagccagcgc attaatggtc
    48481 agatcgcgac gcttaagatc atcttccagc gtgacatccg gtgcggcata gcaagtaaaa
    48541 ccggtgtaac cggaaccgga tttccgttcg gtacgtgcca gcgcatactc ttcatgcgtt
    48601 tgcggatgca gaaacacagg aaaatcgcgg cctacctgct ggtagcccgc gtcgagcatc
    48661 tcctgtggcg tactgccgac caccacccaa tctctgtctt tgaccggtag ccctaacaat
    48721 gcatcccgaa cagcaccacc gaccagataa atcttcacgc catcatccct tcgtcaaata
    48781 cacaattcct aataataaga cagtgcaacg aagaaggcga tttagttcat ccagcgatct
    48841 ttgcgtttgc gcgttgggat caggtgtggc agtaccagac cgagcagcaa gccaagcccc
    48901 agcacgccac cgccatacat aaaccattgc atgatgatgg tgcgctgttt gtcatccagc
    48961 tgtacgctgg cggcatcgac ctttttctgc gcgacaatca gctcgttttt caatttctga
    49021 ttttcttctt ttaatccgtt gatcacgctg tcgctctgcg ccactttttg ctgcatttct
    49081 gcggtgcgct gattccaggt gttatcgata ttggtgagtt tatcggtcag ggttttgacc
    49141 tgattttcca gatctggcac acgggagcgc aggcttggct cagtgctaag ttgtttcaac
    49201 gggatccagg cggtacggcc agagctgtct ttcacctggg cataattggt gttggcgtca
    49261 gtttgtaata aggtcacttc ctcgccggcg ttaaccgtgc ccacgaggcg ataatgatct
    49321 cccggaccgc tacggaccca ggtattcagt tcatcagaaa catagcgcgt ttcttcagcg
    49381 tgtgagacgg cagtggcgct aagtgcgagt aaagttaatc cgatcaggcg taattttggc
    49441 atcaggctgt cgttattgtc atggaaagtg gaacgatagt agtggcatca gtgtcgctac
    49501 gcaaagcatt cgacatcaat cggaatcctc tgtgtcaggt cttgccactg cttcaaactt
    49561 ttacgcccgt caaattgccc gttgcatggc aatttggcgc aaaatactat ctactgacaa
    49621 aaaagatcgc attaagttcg ccgttcatcg tcacttatgt gacataaccg ataagtaaag
    49681 gccatggctc aggaaatcga attaaagttt attgttaatc acagtgccgt tgaggcgttg
    49741 cgtgaccatc tcaatacgct gggcggcgag caccatgacc ccgtgcagtt gctgaatatt
    49801 tactacgaaa cgccggataa ctggctgcgt gggcacgata tgggcttacg tattcgtggc
    49861 gaaaacggtc gctatgagat gaccatgaaa gttgcaggaa gagtgacagg cggcttacac
    49921 cagcgcccgg aatataacgt ggcgttgagc gaaccgacgc tcgacctggc gcagttaccg
    49981 acggaagtct ggccgaacgg cgaattgccc gccgatctcg cttcccgcgt acaaccgctg
    50041 ttcagcaccg atttttatcg cgaaaaatgg ctggtggcgg tcgatgacag ccgaattgaa
    50101 atcgctctcg atcaggggga ggtgaaagcg ggggaatttg ctgaacctat ctgtgagctg
    50161 gaactggaac tgcttagcgg cgacacgcgc gcggtgctga aactggcgaa ccaactggta
    50221 tcgcaaaccg gattacgcca gggcagcctg agcaaagcgg cgcgtggcta tcatctggcg
    50281 cagggcaatc cggcgcgtga aatcaaaccg accaccattt tgcatgttgc ggcaaaagcc
    50341 gatgtggaac aggggctgga agcggcgctc gagctggcgt tagcgcaatg gcagtatcat
    50401 gaagaactgt gggtacgcgg caacgatgcg gcgaaagaac aggtgctggc agccattggt
    50461 ctggtccgtc atacactgat gctgttcggt ggtattgtgc cgcgcaaagc gagcactcac
    50521 ttacgtgatt tgctgactca atgcgaagcg accatcgctt ctgcggtttc tgccgtgacg
    50581 gcggtctact ctaccaaaac ggcaatggcg aagctggcgt tgaccgaatg gctggtaagc
    50641 aaagcctggc agccgttttt agatgccaaa gcgcagagta aaatgagcga ttccttcaaa
    50701 cgctttgccg atatccatct ttcccgccat gccgctgaac tgaaaagcgt tttctgccag
    50761 ccgttgggcg atcgctaccg tgaccagttg ccacgtctga cgcgtgatat tgactcaata
    50821 ctgttgctgg cgggttacta tgatcctgtc gtcgcgcaag cctggctgga gaactggcag
    50881 gggctgcgtc acgctattgc aaccgggcaa cgcattgaaa ttgaacattt ccgtaatgag
    50941 gcaaacaatc aggaaccgtt ctggttgcac agcggaaaac gttaatcagg caaggataaa
    51001 atcgcttatg aagccgctct cttcaccgtt acagcagtac tggcagaccg ttgttgagcg
    51061 gctgccagag cctttagccg agaaatcact tagcgcacag gcgaagtcag tacttacttt
    51121 cagtgatttt gtgcaggaca gcgtgattgc gcatccagag tggctgacgg aactggaaag
    51181 ccaatcgccg caggccgacg aatggcagca ttacgcggca tggttgcagg aggcgctcag
    51241 caatgtgagt gacgaagccg ggttaatgcg cgagctgcgg ctattccggc ggcgcattat
    51301 ggtgcgcatc gcctgggcgc aaacgctggc tttggttact gaagagagca tattgcagca
    51361 gctcagccat ctggcggaga cgctgattgt cgccgcgcgt gactggctgt atgacgcttg
    51421 ctgccgcgag tggggaacgc cgtgcaatgc gcagggcgaa gcgcaaccgc tgctgatttt
    51481 aggcatgggt aagctgggcg gtggggaact gaatttctcc tcagatatcg atctgatttt
    51541 tgcctggccg gaacatggtt gtacgcaggg cggacgccgg gaactggata acgcgcagtt
    51601 ttttacccgc atggggcagc ggctgattaa agtgttggat caaccaacgc aggatggctt
    51661 cgtctatcgc gtggatatgc ggctgcgtcc gtttggcgaa agtggcccgc tggtgctgag
    51721 ctttgccgcg ttggaggatt attaccagga gcaggggcgc gactgggagc gttacgcgat
    51781 ggtcaaggcg cggattatgg gcgatagcga aggcgtctat gctaacgagt tgcgtgcgat
    51841 gctgcgcccg tttgttttcc gtcgttacat cgatttcagc gtgattcagt cgctgcgcaa
    51901 catgaaaggg atgattgccc gtgaagtgcg tcgacgtggt ttgaccgaca atatcaaact
    51961 cggcgcaggc ggcattcgcg aaattgaatt tatcgttcag gtgttccagc tcattcgcgg
    52021 tgggcgcgaa ccgtcgctgc agtcgcgctc tttactgcca acgctcagcg tcattgccgc
    52081 gctgcatctg ctttctgaaa acgatgctga acaattgcga gtggcgtatc tgttcctgcg
    52141 gcgtctggaa aacctgctgc aaagcattaa cgacgaacaa acccagacgc ttccttctga
    52201 tgagcttaac cgtgcgcggc tggcgtgggc gatggacttt gctgactggc cgcaactgac
    52261 cggggcgctg accgcacata tgaccaatgt gcgccgggtg tttaatgaat tgattggcga
    52321 cgacgaaagt gaaactcagg aagagtcgct gtcggaacag tggcgtgagc tgtggcagga
    52381 tgcgttgcag gaagatgaca ctacgccagt gctggcgcat cttagcgagg atgatcgcaa
    52441 acaggtgcta acgctgattg ccgatttccg caaagagctg gataagcgca ccatcgggcc
    52501 gcgaggacgt caggtgctcg accatctgat gccgcatctg ctaagtgatg tctgtgcgcg
    52561 tgaagacgct gccgttacgc tgtcgcgcat taccgccttg ctggtgggga ttgttacccg
    52621 caccacctat ttagaattgc tcagtgaatt ccccgcggcg cttaaacatt tgatttctct
    52681 gtgtgccgcg tcgccgatga ttgccagcca actggcgcgt tatccattat tgctggatga
    52741 attgctcgat ccaaacaccc tttaccagcc gacggcgacc gatgcctacc gcgatgagtt
    52801 gcgccagtat ttgctgcgcg tgccggaaga tgacgaagag caacagcttg aggcgctgcg
    52861 tcagttcaaa caggcgcagc tgttacgcat cgccgcagcg gatatcgctg gtacgctacc
    52921 ggtgatgaaa gtgagcgatc acttaacctg gctggcagag gctatgatag atgccgtcgt
    52981 tcagcaggcg tgggttcaaa tggtggcccg ctacggtaag ccaaatcacc tcaacgatcg
    53041 cgaaggccgt ggttttgcgg tggtcggcta cggcaagctg ggcggctggg agttaggcta
    53101 cagttccgat cttgacctga tcttcctcca tgattgccca atggatgcga tgactgacgg
    53161 cgagcgggaa atcgacgggc gacagtttta tctgcgtctg gcgcaacgca ttatgcatct
    53221 gttcagtacg cgtacctctt ccggcatttt gtatgaagtg gatgcacggc tacgcccgtc
    53281 cggggccgcg ggaatgctgg tgacatccgc agaagcattt gccgattatc agaaaaacga
    53341 ggcctggacg tgggaacatc aggcgctggt gcgtgcgcgg gtagtgtacg gcgatccgca
    53401 gctcaccgcg cactttgacg cggtgcgtcg cgagattatg acgctgccgc gtgaaggtaa
    53461 aactctgcaa acggaagtgc gggaaatgcg cgagaaaatg cgcgctcatc tcggcaataa
    53521 acatcgcgat cgctttgata tcaaagctga tgaaggcgga attaccgata tcgaatttat
    53581 tacccaatat ctggtgttgc gctacgctca tgaaaaaccg aagttaacgc gctggtcaga
    53641 caacgtgcgc attctggaac tactggcgca aaacgacatt atggaagagc aggaagcgat
    53701 ggcgctgacc cgtgcttata ctacgctgcg cgatgaactt catcatctgg cattacagga
    53761 attgccgggc catgtgccgg aggattgctt caccgcagag cgtgaactgg tgcgggcaag
    53821 ctggcagaag tggctggtgg aagaatgaag tatggtatta tcgcgcgcaa attttgaatc
    53881 tctcaggaga caggaatgaa agtaacgctg ccagagtttg aacgtgcagg agtgatggtg
    53941 gttggtgatg tgatgctgga tcgttactgg tacggtccca ccagccgtat ctcgccggaa
    54001 gcgccggtgc ccgtggttaa agtcaatacc atcgaagaac gtccgggcgg cgcggctaac
    54061 gtggcaatga acatcgcttc tctcggtgcc aatgctcgcc tggtcgggct gacgggcatt
    54121 gacgatgcgg cgcgtgcgct gagtaaatct ctggccgacg tcaacgtcaa atgcgacttc
    54181 gtttctgtac cgacgcatcc gactatcacc aaattacggg tactttcccg caaccaacag
    54241 ctgatccgcc tggattttga agaaggtttc gaaggtgttg atccgcagcc gctgcacgag
    54301 cggattaatc aggcgctgag ttcgattggc gcgctggtgc tttctgacta cgccaaaggt
    54361 gcgctggcaa gcgtacagca gatgatccaa ctggcgcgta aagcgggcgt tccggtgctg
    54421 attgatccaa aaggtaccga ttttgagcgc taccgcggcg ctacgctgtt aacgccgaat
    54481 ctctcggaat ttgaagctgt tgtcggtaaa tgtaagaccg aagaagagat tgttgagcgc
    54541 ggcatgaaac tgattgccga ttacgaactc tcggctctgt tagtgacccg ttccgaacag
    54601 ggtatgtcgc tgctgcaacc gggtaaagcg ccgctgcata tgccaaccca ggcgcaggaa
    54661 gtgtatgacg ttaccggtgc gggcgacacg gtgattggcg tcctggcggc aacgctggca
    54721 gcgggtaatt cgctggaaga agcctgcttc tttgccaatg cggcggctgg cgtggtggtc
    54781 ggtaaactgg gaacctccac ggtttcgccg atcgagctgg aaaatgcagt gcgtgggcgc
    54841 gcagataccg gctttggtgt gatgaccgaa gaggaactga agcttgctgt agcggcagcg
    54901 cgtaaacgcg gcgaaaaggt ggtaatgacc aacggtgtct ttgacatcct gcacgccggg
    54961 cacgtctcct atctggcaaa tgctcgcaaa ctgggtgacc gtctgattgt cgctgtgaac
    55021 agcgatgcct ccaccaaacg gctgaaaggg gattcccgcc cggtaaaccc actcgagcag
    55081 cgtatgattg tgctgggcgc actggaagcg gtcgactggg tagtgtcgtt tgaagaagac
    55141 acgccgcagc gtctgatcgc cgggatcctg ccagatctgc tggtgaaagg cggcgactat
    55201 aaaccagaag aaattgccgg gagtaaagaa gtctgggcca acggcggcga agtgctggtg
    55261 ctcaacttcg aagacggttg ctcgaccact aacatcatca agaagatcca acaggataaa
    55321 aaaggctaac cggaaagcgg ttcacagatc tcgcttcgta gcaggcaggc ctattgacgc
    55381 tgttgttttt tcaacctaaa gtaaaggaac aagggtaagg gaggatttct cccccctctg
    55441 atcagttgtt agtaagtcgg gaaacttaac agtaacaaca caaccagtat gatgacgaac
    55501 ttcatcataa ccctttcctt ctataaggcc ccttcctcgg gaggggcttt cccgtttcag
    55561 ccccttgctg actccccgat tgttgatgag cgccggaccc cgcgcaacgc tttccctgaa
    55621 gcagttttgc cttccccgag cggtcacgca aaacgctgca acgtcctgag catttgcacc
    55681 ttttagcgga acgcagatat aaaaaatccc cggctttttg ggccagggat atgtgttaat
    55741 gaaaccttct tgacgctgat tttttttcaa cctaaagtaa aggaacaagg gtgagggagg
    55801 atttctcccc cctctgattg gctgttaata agctgcgaaa cttacgagta acaacacaat
    55861 cagtatgatg acgagcttca tcataaccct ttccttctgt aaggcccctt cctcgggagg
    55921 ggctttcccg tttcagccct ttgctgactc cccgattgtt gatgagcgcc ggacctcgcg
    55981 caacgctttc ccagaggcag ttttgccttc cccgagcggt cacgcaaaac gttgcaacga
    56041 cctgatcatt tgcagttttt agcggaacgc agatataaaa aatccccggc tttttgtgcc
    56101 agggacgttc atagctgaaa atttattcta cgttttcggc gacgggagtt gttgaggtta
    56161 agggtgaagt caatgccgcc agtgagccgc ctgaaacgcc aatttcattg agcaaggagt
    56221 caatcagcgg tgcctgtgtg cggtaagaga gagcggctga taatgcttgt tccgccaggt
    56281 ttccgccccc cacattaccc gtgtttgcat cacccgcagc gctgccacga ttcagaccat
    56341 cgacctgaat aatcttgata ccgtcaatag atttcatcgg ctcaacggat ttttctatta
    56401 ccgcaggtag cgcctgcaac aaggccagtt tgaatttaag gctggtttgt tcatcagaaa
    56461 gtacgttgat agcatcgttc agcgcacgtt gtgcttctgc ttccgccaga ccctttttac
    56521 gtgtagcttc ggctaactca acgatagccg ccgcctgcat ctctgcggct tctttttctg
    56581 ctttcgcccg cacggtcagt tcaaccgctt tggtttctgc atcctgcgcg gcagcgatta
    56641 gggcaacttg tttagcacga tcggcttctg cggtctggcg agtggtttct acgttttgtt
    56701 gcgcacttac tgcttctgcg agtgcaaggt tagcacgcgc ttctgcctgg gactgttgtt
    56761 ccgatttggc ggcaatagcg atcgatttcg tctggttggc gatttcggtg acctgctgtt
    56821 gttcgatctc tttaatacga acttcacgtt cagcctcaac ctttcttgag cggacggcct
    56881 gctcgcgctc gatctccgtt tcctgaattt gtcgttcagc cagaattcgc gtctgctctg
    56941 cttcacgacg acgttcagct tcaaaagccg caatacgtgc attctgttcg gcagtacggg
    57001 ttttaacctg ctgctcctgc tcaagcgtca taaacgcttc ttgttgttca atctccaact
    57061 tgcgcgaaag tgcatcacgg tttttctcac gcaccgcaac ttctacatcc tgttcaactt
    57121 cgttacgttc gcgacgacgg cgctccgtct cctgagtcag tttggttaaa ccttcggcgt
    57181 caaaggcatt gttcggattg aaatgttctt tcgaggtctg gttaaagttg gtaagtgaaa
    57241 cgctttccag ctcaagaccg tttttcgaca ggtcttctgc gacagtattt tgtactccct
    57301 gcacgaagtt ctcgcgggta tcctgtaact catgcatggt catttgtgca gctgttgcac
    57361 ggagggcatc gacaaattta tcttcaacca acatacgtaa gtcttctggt gatagcgtgc
    57421 gttgccccaa cgtctgcgcc gcagtggcga tgccttctac agacggtttt acccgtacaa
    57481 agaaagcgac tactacatcg acacgcatac gatctttcgt aatcaggcta tcaatggttg
    57541 agcggctgac ttccagcttc agagtattca tattgatggg gattatttca tgaaagatcg
    57601 gcatcacgat tgcgccaccg ctcatcacca ctttttgccc acctaaacca gtacgaacaa
    57661 aagcttgctc tgccgaagcg cgacgataga gcctggcgaa aataattcca ataataaaca
    57721 gaatgcatac ggcaataatc gcggtaaaca tccaggaggg cacagaatta acaatatcat
    57781 ccattattaa atttcctttt gattaataaa ttacaatatt tgtggccagg gattgttttc
    57841 cgccaaatat cgcgttgcag aaagtcggca aataattaac actttgtctc ctttagtgaa
    57901 aaattttcct tcttcaggct ccagtagtaa ataatgtatt tggccaaatt gatcggtgag
    57961 ttttccttcg cagggattac ctgaagtggc ttgatgaccg gtaattaatg ccatgctacc
    58021 aatatattct tcttctgtaa tagctgaact atggtcgcgt ggaatccagg gcgcaactat
    58081 tttaccggta taatgcaccg caataatcgt aaacagtaaa ctgacaggaa ccacgaacag
    58141 gttcgacagt ggtgattgcc agaccatgat gcaggcatgc tgcaacagga tgccaataag
    58201 accaaaaaaa ccagccagca agcagagaac gacgagagct ggcaatcttc cgatattgag
    58261 ataatgaagt gcctggctaa tatgacctgt ggttatggaa tcataatggt caagatgtgc
    58321 atcaagagca ccggagagca tgtgaccgca gataagcgct aaaatttcta aaaggccgat
    58381 caacagtaca aaggaaatag cgaaaagata aggggtatta tagtcggcga ataaaatcat
    58441 atgtcactcc aatgtccatt tagtgacgca atatttactt tgggatagtt tccttgctta
    58501 catttatctt tgttaataat aacacatgtt agagaagttc tggaagagaa agttttttaa
    58561 tatggttttt tatttttcac taaaaagtgt gatcggggac aatatattta cgcacgttat
    58621 gtttaaaggc actacactga ttggggaata ctgaaatcag aaaaagcata tggccttaaa
    58681 aggtatgcga taaccggagg atgtgcttat ggatcatagt cttaattctt taaataattt
    58741 cgatttcctg gcgcgtagtt ttgccagaat gcacgcagaa ggtcgcccgg tcgatattct
    58801 tgccgttact ggtaacatgg atgaagaaca tagaacctgg ttttgcgcac gttatgcctg
    58861 gtattgtcaa cagatgatgc aggcaagaga gctggagtta gagcactgat ataacgggcc
    58921 tgatggcccg ttttagtgtt tgtattagat gctagttata ggtgattttg aggatgacgt
    58981 ctttactaaa cggtccctca acaacagtct ctgccggatt cgcactaagt tctgccctga
    59041 atggtgcggt gaccgaaggt gcactagacg atgaaaaaga agcaaattgt gagaagcggt
    59101 taaattccgt tgctgttcca tctttatgaa atatcttcaa tagcagtcca ttacccatat
    59161 ccagatggct ataatcactc aaaatatccg tagtgaaaaa gctccctaaa atattgaatt
    59221 gctcagtaca ggccgcacca ggatcttttg tcatgactac actaaacgtc tcactaacgc
    59281 tggtattttt aattgttcgg gaatttattt taccaaagtc aacaacgcca tcagctggtt
    59341 ccagtgcgac attaacaaag cagtcaagga catgaatatt atttaatcca cgaatcctga
    59401 aggtcaaatt tttgtctact tctatagctc ctgcgccact cataccttta aactctagag
    59461 cgatatattc atcaggtaac accaggtttt tattaactct attggcattt tttgctaatt
    59521 taatatagag ttgtacgcga gctggaaagg ttactgataa ttgaggctca ggacctccac
    59581 tacagacagc ggggttttta tagtgattat taaaggtacc cgctcctttt atatcaatgc
    59641 attctggtgc tgcgatagca ttaggggcag tcgaatcata atcaactcca ttgtatgtta
    59701 cgccaaaaat ataggagttc tgattataaa agtcctgacc gcctggtaaa aacatcatta
    59761 tattagtcca ggctgatggg tattcttctc caggtgatgg ggcaggtaat gcattattac
    59821 agaagacatt cataaaatac tcactgcttt gccagatctt atcacctttt ttaccattac
    59881 tggggataga aattcttggt acgtaaccaa tgactacggt atttccccct tcatgttcag
    59941 catagcagtc cattgcccat acaggtaatg cactaaaacc tataataaat ataattacaa
    60001 ttaataagta gcgcatatta tttatctcgt ttggctacgg aaacattaca agagttatta
    60061 accgtcgggc agtttatttc ataaaaactt aatccaccaa aatcattgat ataaccaacc
    60121 tgaaaagctg acggaacatt tttaaactgc gtatctgcat ggctataagg ggttaccatt
    60181 aaactttgcg tttgtggcaa cattgtgatt ccgtttgttc cgatataacc cagcgtaacg
    60241 tgataaggca tcttattgtt aaagcggatc gaaccatcat ttctacggat gatttcaact
    60301 ttttcgtaag acattacccc atcatcttct aattcaatag cttttggtcg ccagaatagt
    60361 ttcaatgcgt gctgcatagt gacttgcatc acattttttt tatctgtttt tggcggtatt
    60421 tctcgcacgt taaaatagaa gagcgtttct ctgtcattag gcagttgagc aattttttcc
    60481 tgacttatca ttcttatttg aatttgctca ctgggattta aacgtaccat agggggaacc
    60541 gtgacaataa agtcacgtga tttattgcct ttcgtatctt ctatccatgt ttgcgccaga
    60601 tagggtagat ttttgctttg attagtaagt tttaatgctt cccctttatc tgactcattc
    60661 attatgatac gggtacggtc cgggatgatg gcaccccagg caatgctgct catgcaggcg
    60721 agtaatactc ctgctgcaat gagattcttt gtgtttaagt agcgcattag tttcatcctg
    60781 aattaatttt ggctaataca cggtaaaata accgttccgg tggttaagtt gctgctattg
    60841 ggtggttgaa taaaacagga tttatcaccc cagcgtaaag taagtttgct gtcatcctga
    60901 atgccgttga ggtatacaaa gccgccatca gcaaccagtc ctaattcttt atggctggtt
    60961 ttatctttta cgctaatccc cagtggtggg tgactaccat ctgccaggcg aataaccccc
    61021 atgatttgat agcccttgcg ggtatcaagt ttggcgtagc caatagcacc ttcggttaag
    61081 gtggtggtga taaccgagtt ttcgatatcc acattttctg gaagatttcg ggtatcaacg
    61141 cttaatgatg ttgttatgta actgctgact gatggaataa ctccgatgcc ataccgatta
    61201 gttaccgcgc gtttattgtt caacggaata tcttctgcac catctgcgtc gatcataaaa
    61261 cgcgagtcag cactaccact atagtcatgg aaagcggctc cgtgacgagt cgccgtgaat
    61321 gaaccattcc aactggcatt cagagaataa taactgtctc gctgtgatgt cccggagaga
    61381 tagagacgac cgttctcggt attatgctga taactggcgc gtagtgacgc tttcatatct
    61441 ttgaattcat cattgtcgcc tgaagcagaa acgctccagg aattatttcg atcggaagag
    61501 tcataccacg aagcagtatg cgaaatcttg ttatcctgat ttcgttgcat accatagctc
    61561 aatgttctac tggttcccca gggaatcgaa atatttaggt acagttgatc ctggttgtct
    61621 tcttcccagt ttattcggct aaatgttaga gaagtggaga cgttttttaa tggcccgata
    61681 tcaaaatcgc ggctaagtga taatgaataa ttcacattac tgctggcgtc ccagtaagta
    61741 ttacgagcca aacttacgta tgtatttaac cttaatgatt caagatactg gttaaacgtg
    61801 acaatataac tctctttttc attctgataa ttcgtgtaat ggttagtgtc attgatatat
    61861 tcattcattg tcacaaagtt tttatcagag aaacggtaac cagcgaaagt gagctggcta
    61921 ccggtagatt caaaacgttt tgaatagtta gcgcggtagc tataacccgt ttctttatcc
    61981 tgattatgca actgagcatc agatcgtgtg acatcaaaag ataatgaacc caatgagtta
    62041 aggttaaagc caacgccggc agccagagat tgataatcac ggtttgttaa aactgaacca
    62101 ccatacaggg atacattgtt cagccaaccc catgagaatt caccagtcca gaagaagggt
    62161 tgttgtaagg aatcaccacc aacgctggtc ggtttaccca tagcagtggt gtagcgaatc
    62221 tgccctttac gcgtcagata aggaatacta ttagatgcaa cttgccattg cgtgacttgc
    62281 ccgtcctctt cttcaacctt gacgtccagt tgcccctgta atgtattgaa taaattagta
    62341 atagcaaatg ggccaggagg aacattttct tgataaataa tacggttgtt ctgtgagaca
    62401 gtgacctttg cattcgtttg tgcaacaccc gtgatttgcg gtgcgtaacc acgtagatca
    62461 ggcggcaaca tattctcatc gcttttcaac gaaacgccag aaaaatggaa agagtcgaaa
    62521 atagaggatt cagtatcgta ttgacctata gttagttttg cattaattgc tgggattggg
    62581 cgaaacaaat aaatacgcgg aaaatccagg ttgttcgcct ggcttttgcc attgttaaat
    62641 gactgatcgt actggtaatc agtacgcagg cgccaggccc caagattaac cccagcctgc
    62701 ccataggaac ttatattttg tgaattatcg ccctgatgtg gtgcataatg agaggcatat
    62761 aaattgtagt caagaaatgc cccagcaata ccatgatccc aaagttcagg aggcgtccag
    62821 tttgcatctt tgtattttaa ccatgcctga ggtgcagata tggataattg cattttccct
    62881 ttatcgagat aagttgtaat ttgtttttct ttttcgatag ggtaacaacc atcgatcagg
    62941 ttttgctgag ccacttcaat aatctcatca gtaaagccta ataatgttaa ttgctctgga
    63001 gtcagacaaa ctgcagtttg gttatcaatt aatacccatt gcaggtccag atggattggc
    63061 gtccttttat tattaataag agcgtttaat gagtatttac ctacgggtaa ttggccatca
    63121 gtttcaaatt gggaaaggtt aacgttttca cgatcttcgg cttcgattaa atctttgttg
    63181 aattcaacgg cataagctga cgcacaacca atgatgagaa cggataatga acaataaata
    63241 tttttaatca attcgcttat tgtggttaat tttaattttt tatacatctg ttccacttat
    63301 cattaatccg ttaatgatgt ggccgggcga acccggccta atgtgattac tcgtaagcaa
    63361 tcttatagtc agcctgagcg taaacgttgc ccggggtagc atctttgctt ggggattcca
    63421 tacgagcttt gaagttcagt tcctgatagc tgttagtatt gttgaatgta attactaccg
    63481 gagtacctaa agtcacttcg ccgctctggc tatccagaat acgtacgcca acgcctgtgg
    63541 caccaccgat ttcagtttct ttggtgtttt tcagcaggtc agtctgaccc gtcatagtat
    63601 tcgctgtggt gaaagtaacc ttcgcttttg aataagtggt tccaccctgg ctcaacatgc
    63661 agtcttgcag gtgaatagtg aaaggctcag ccaaagattt ctggtcgctt ttcagaacgg
    63721 tatctgctac ttcacccaga tttacagtta agtcttcgtc acctggttta attgaacatg
    63781 gagcagagat aacttcacct ttaaatttaa caatgccgtg accttcgtca gcaaatacgt
    63841 tattggaaag aatcattgct acgccagcaa caagaagtga ctttttaaaa gcagacataa
    63901 tattcc
//
LOCUS       DAZUDJ010000019        63520 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.019, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000019 DAZUDJ010000000
VERSION     DAZUDJ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 63520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63520
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.019"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..114)
                     /locus_tag="ACHY1N_001731"
     CDS             complement(<1..114)
                     /locus_tag="ACHY1N_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309806.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFS4044055.1"
                     /translation="MLKQQDMTETARVVFNELSVTDPATVGEIAQNTYLSRE"
     gene            complement(337..891)
                     /locus_tag="ACHY1N_001732"
     CDS             complement(337..891)
                     /locus_tag="ACHY1N_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1133 family protein"
                     /protein_id="HFS4044056.1"
                     /translation="MIYPEITGKSGEHLRLKTLESVWIQGKLRMWGRWSYIGDGKTGN
                     MFNQLLTSKKLTKTAINEALRRMKRAGLDKPELEAFLRDMINGNQKSWLAHCTDSEAL
                     IIDRVIGEVLAGYPGLFNVLSQRYLGRGMTKRKMAELLNDAHPEWSLRTCERRIEHWL
                     KVAEFILYKPMVMAFGIEKKVIAF"
     gene            complement(900..1259)
                     /locus_tag="ACHY1N_001733"
     CDS             complement(900..1259)
                     /locus_tag="ACHY1N_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFS4044057.1"
                     /translation="MRHEFILPYPPTVNTYWRRHGNTYFISEAGKRYRRDVALIVRQQ
                     RLKLNLSGRLAIKIIAEPPDKRRRDLDNILKAPLDALTHAGLLIDDEQFDEINIVRGQ
                     LVSGGRLGVQIYKIESE"
     gene            complement(1259..1516)
                     /locus_tag="ACHY1N_001734"
     CDS             complement(1259..1516)
                     /locus_tag="ACHY1N_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044058.1"
                     /translation="MNNQTMTFTPEQLRKQAQEMLRQAEQLEKTGVTKDAIRRDMVPA
                     LRELMQAKHRAQKAVDELVDCVAELETKVGKFEKMVQEVLR"
     gene            complement(1513..2913)
                     /locus_tag="ACHY1N_001735"
     CDS             complement(1513..2913)
                     /locus_tag="ACHY1N_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFS4044059.1"
                     /translation="MTNPTNPVWRNDDLEGAVIGAFFLRGADPEVMDILATLPAEVFS
                     VRPYRDIYRGICRQARVSGVIDPVLLCNEMPELAPVITDTGRKTWVKSSLEHYVTALR
                     RNAALRDAEKTLNEALQKLRDANTCDAAEDALKDAQNMIVSLSTGKGVIQPVHIDDVL
                     PEVVERVECRNQGLEKSRTLMTGIDELDAKTGGMEPGDLVFIAARPSMGKTELALDII
                     DKVTEQEHGVLLFTMEMANIQIGERMVSAAGGMPVSRLKSVARFEDEDWARFSQGVGR
                     MTGRNIWMVDQANLTIDEICATTKHHLIKHPETALVVVDYLGLIKTRTTGRHDLAVGE
                     ISKGLKGLAKFGGLPVVALSQLSRAVESRPNKRPMNSDLKNSGEIEADADIILMLYRD
                     EVYNPDTQARGIAEINITKQRNGSLGTIYRRFYNGHFLPVDQESAQILSTPMQQPQPR
                     RYSNKRTDSSKMERFF"
     gene            complement(2910..3800)
                     /locus_tag="ACHY1N_001736"
     CDS             complement(2910..3800)
                     /locus_tag="ACHY1N_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4044060.1"
                     /translation="MTNFLNKQYMQHDKAQLLNRKADLEEELAFVRGGKRPWRCEHWV
                     QSTETVSCGKHGKYTRYVLTGPDVRGKAVKRVSGCLSCLSEELDCVYDELRALKVREL
                     LDQAAIARRFQDCEFDNYQAVNTDAQKNLEACQRYAASWKKCLAAGTSMIMIGNCGTG
                     KNHLAVSMAKNIIRHHLATVEITDVMRLTRAVKNTWRHNSERTEDEIIDHFVSLDLLI
                     IDEVGVQFGTPAEITILQEIINARYESVLPTILISNLTFEQLKESIGERIVDRVTDGG
                     RNCLVFGWESYRAHIRGVAA"
     gene            complement(3818..4711)
                     /locus_tag="ACHY1N_001737"
     CDS             complement(3818..4711)
                     /locus_tag="ACHY1N_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFS4044061.1"
                     /translation="MRPSDLLLDFGHPVAYYPGLVKYMGSPHAVIFFGQIFYWQDKAH
                     AAEGVHKTREEIQHETGLTFEQQAVARKHLVSRGILVETNKRLEHKMFYRIDCERLNE
                     IINENNQFSRNGETRFRGTVKPDFAEEGKPSPRTRETPRRGEGKTNFDLTENTTEITS
                     ENTTESKNTIGASADASAPARSARQEYSPEFEQAWQEYPKRAGGNSKSAAFKAWKARI
                     REGIKPETMLDGVKRYAAWVRATGNTGTQFVKQAATFFGPDRHFDESWQQPAAPGGGR
                     GKSLPISGFSEQDYGSTNFNW"
     gene            complement(4698..4931)
                     /locus_tag="ACHY1N_001738"
     CDS             complement(4698..4931)
                     /locus_tag="ACHY1N_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044062.1"
                     /translation="MIRYIVNSLYHRYNRCPRVGQWFTTSNGHVLRVCLVNTESQKVV
                     CQVQGRTHTRSYPLVAFQSGKMFKRLGGGYASV"
     gene            complement(4928..5122)
                     /locus_tag="ACHY1N_001739"
     CDS             complement(4928..5122)
                     /locus_tag="ACHY1N_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044063.1"
                     /translation="MISYEIIISTTEYRNDVSVRTDVSVWHRRYKSRKTAELKAAEMC
                     ETISMKGSPVKYVTTAEVRP"
     gene            complement(5119..5781)
                     /locus_tag="ACHY1N_001740"
     CDS             complement(5119..5781)
                     /locus_tag="ACHY1N_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HFS4044064.1"
                     /translation="MIISRPNIDSAISGRYTVSAPYKAGAGIGVLELIKAIYDAPASF
                     LSSAFAHIKVMVGWAGASKDAPVSLITGYANPVQFTTSEIGVSGGGSISPIKEAAIMA
                     TVPTHSFLKIESVNGKAVIFSLHVACHFKRMHQNIVDKIEYLNCSREFFTRNFIPCTY
                     HLYGDSLRGYYITLDGLMMLQLGLSLRTMRYYESCIEVFHEAETGLNHTDFHRNQWEV
                     RP"
     gene            complement(5890..6597)
                     /locus_tag="ACHY1N_001741"
     CDS             complement(5890..6597)
                     /locus_tag="ACHY1N_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001435006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HFS4044065.1"
                     /translation="MNTAIFNGKASMTSVEIAELVGSQHSDVKRSIERLVAKNIIRKP
                     PMAVSEKINNLGFKVQYEHYLFEGEQGKRDSIIVVAQLCPEFTARLVDRWRELEEQIR
                     KPMSEIEMVAAMALEAVRQQKRITQVEEKVSHVAETVEQIKKGTIREGYAGYRQLKAK
                     TGLSDDKCCNLVNAYQIPTDTHEFMTSDGLLSRRAIVAVEPFMAAFYRVMEEAEPRGT
                     RWYHPKMGLFQVIGWQR"
     gene            6717..7010
                     /locus_tag="ACHY1N_001742"
     CDS             6717..7010
                     /locus_tag="ACHY1N_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044066.1"
                     /translation="MKVQAVGLFWFRDAIQYHELKNIFTDADVLSDSYTEWKHDAEKL
                     IKRVERGGQRVIKVEADTAEFIAWCTSEGIGINAEGRMQFASFKAYQQLLSER"
     gene            complement(7081..7353)
                     /locus_tag="ACHY1N_001743"
     CDS             complement(7081..7353)
                     /locus_tag="ACHY1N_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4044067.1"
                     /translation="MKGNDYDKLRTLIAQNAIARNLGVTPQAVNQWFSKNTIPARFVL
                     RVCEVVAWKVTPHGLRPDLYPHPEDGVPDSLRKISNPSLAHTEDGK"
     gene            7487..8176
                     /locus_tag="ACHY1N_001744"
     CDS             7487..8176
                     /locus_tag="ACHY1N_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFS4044068.1"
                     /translation="MKNVKNTENRIAAMLKAKGWTQAQLARKLGVSAQSVQYWTTGKT
                     FPRSDKLAHLSEISGYPQSWFLGEDSSPTFSSQEKHQTRTDSVVFNVLDVEFSCGDGT
                     HVRGDLIDVVRSIELDPEYARRLVGNRAFKNIEIGNARGDSMAPTISPGDLLFLDKTV
                     TYFDGDGIYAFCFDGECYVKRLQKIGSKIMVLSDNPNYQPWSIEKEGLALLYIQSKVI
                     SSIPFNINRFG"
     gene            8321..9013
                     /locus_tag="ACHY1N_001745"
     CDS             8321..9013
                     /locus_tag="ACHY1N_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4044069.1"
                     /translation="MKTLNATPETTNFINCGCVSLKGLELDSFALNIANLLSAVRTFH
                     LLDCARSKELGIEVMEFIHEYALSAASPAQQKQSFPESWLVNLRTQREACGLTTAELA
                     RLLDLDEEIIIQWESGEYEPTISMLTPLANVLGCDPLSLLSEKNSESVIRVNAPEVHV
                     ENIGARIKSARKKLGLTEADLARMIHTYSDPINDWECGTCEVPADQIVPLASALNCDL
                     MWLLTGKSEAKE"
     gene            9019..9219
                     /locus_tag="ACHY1N_001746"
     CDS             9019..9219
                     /locus_tag="ACHY1N_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044070.1"
                     /translation="MTGNIHDKYEGLCLAPDSFANNIHNLLCAVIVLQMSDNDAIKRT
                     GDEVLEFARCYAEAASEKELSS"
     gene            9419..9778
                     /locus_tag="ACHY1N_001747"
     CDS             9419..9778
                     /locus_tag="ACHY1N_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044071.1"
                     /translation="MAYEPINTYRRRIAVAALHRIKRKTGGNLLIVDLPDGSITTIEI
                     TEQFINQLLLRFEGITRGELGRVEGETEFRTAYQNAIGINQHTEYQAETGKLIIDNLL
                     QEVIDYAKEKYISGGIN"
     gene            9778..9993
                     /locus_tag="ACHY1N_001748"
     CDS             9778..9993
                     /locus_tag="ACHY1N_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044072.1"
                     /translation="MANLSPVSVVHEKVQIVMTIENGQVTDVCKVRDGELIASMDTFI
                     WLAERAGYQITAPAQEETSDINSNANS"
     gene            10180..10572
                     /locus_tag="ACHY1N_001749"
     CDS             10180..10572
                     /locus_tag="ACHY1N_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044073.1"
                     /translation="MIDNRTASAIDQALQKHDTPVGPLFFVTRHGRTKKCLTRKTAIR
                     YLAFFMTTRAFERSGFRQRHPDKRFIFNGNEIWKRGESTTEYTRAHQRTIRRLRRLIA
                     RKQYTEKWFRKYDTWSAGYYELMATKPF"
     gene            10633..10821
                     /locus_tag="ACHY1N_001750"
     CDS             10633..10821
                     /locus_tag="ACHY1N_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044074.1"
                     /translation="MNIYFKIVISLAIISCIYGLIVPALISMKDTVAVISGFALACLT
                     PPCICAIYKGLSFTKDKR"
     gene            10818..11148
                     /locus_tag="ACHY1N_001751"
                     /pseudo
     CDS             10818..11148
                     /locus_tag="ACHY1N_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707752.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11190..11561
                     /locus_tag="ACHY1N_001752"
     CDS             11190..11561
                     /locus_tag="ACHY1N_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001695578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFS4044075.1"
                     /translation="MNTHNTQPQIMNYDPNLTSCGRMAKQTVRLTFGLWEYRETFEVT
                     VGGNLTGLDVISCAIESLYATLPYEEVEDERTGETDIMATINIGELICQDEDLSGELW
                     LAGMLISAEIISIEPATNIRL"
     gene            11593..11835
                     /locus_tag="ACHY1N_001753"
     CDS             11593..11835
                     /locus_tag="ACHY1N_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HFS4044076.1"
                     /translation="MFSLINQGQLYTDNADYPVKIVRCINNTVLYRRMDGRTQSVKIN
                     DFNELFERIDHQEYRQILAETEQEAHLKKLRAMKRK"
     gene            11839..11985
                     /locus_tag="ACHY1N_001754"
     CDS             11839..11985
                     /locus_tag="ACHY1N_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044077.1"
                     /translation="MNKAFELWVRQRYGNRYDLTRDVDGFYCREIVKRMFEVWCHCRG
                     LSVV"
     gene            11994..12230
                     /locus_tag="ACHY1N_001755"
     CDS             11994..12230
                     /locus_tag="ACHY1N_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family protein"
                     /protein_id="HFS4044078.1"
                     /translation="MSNVIQLAPNEWVCESVLIAITGLKPGTILRARKECWMVGREYI
                     HVSPDGNPKPSSECMYNRKAIDAWVASMKNKQPG"
     gene            12286..13599
                     /locus_tag="ACHY1N_001756"
     CDS             12286..13599
                     /locus_tag="ACHY1N_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4044079.1"
                     /translation="MDKVKYPTGVENHGGTLRIWFNFKGKRVRENLGVPDTAKNRKIA
                     GELRTSVCFAIRTGNFDYAAQFPDSPNLQAFGVSKKEITVKELEEKWLDLKRMEISAN
                     AFNRYESVARTMVPKIGGSRLVSTVTKEELLYIRKDLLTGHQNPTKGKAPVKGRSVVT
                     VNYYMTTIAGMFQFAADHGYLEANPFEGIKPLKKARAEPDPLTRDEFIRLIDACRHQQ
                     TKNLWSLAVYTGMRHGELVSLAWEDIDLKAGTITIRRNYTKLDEFTLPKTEASTNRVI
                     HLIQPAISVLKNQAEMTRLGKQHHIKVQLREYGRSVNHECTFVFNPQVVRKSKQVGFI
                     YKVDSIGDSWESAIKRAGIRHRKAYQSRHTYACWSLSAGANPSFIASQMGHASAQMVF
                     NVYGAWMTDSNAEQIAMLNQKLADYVPMMSHGHQSDTRDLLKSVG"
     gene            13581..14351
                     /gene="yecE"
                     /locus_tag="ACHY1N_001757"
     CDS             13581..14351
                     /gene="yecE"
                     /locus_tag="ACHY1N_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFS4044080.1"
                     /translation="MKISGLAFNTRHVNCVEGNTTLYALPKPEVVLRWREQTTDDFRF
                     CFKFPATISHQAALRHCDDLVTEFLTRMSPLAPRIGQYWLQLPATFGPRELPALWHFL
                     DSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNRVILDGRPVHAACPHSEAIR
                     DAQRKKPKVPVHAVLTATNPLIRFIGSDDMTQNRELFQVWLQKLAQWHQTTTPYLFLH
                     TPDIAQAPELVHTLWEDLRKTLPEIGAVPAIPQQSSLF"
     gene            14404..14799
                     /gene="yecN"
                     /locus_tag="ACHY1N_001758"
     CDS             14404..14799
                     /gene="yecN"
                     /locus_tag="ACHY1N_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HFS4044081.1"
                     /translation="MVSALYAVLSALLLMKFSFDVVRLRLQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRS
                     GMSATWCALLLMVLANLWYMPWELVFSLR"
     gene            14840..15583
                     /gene="cmoA"
                     /locus_tag="ACHY1N_001759"
     CDS             14840..15583
                     /gene="cmoA"
                     /locus_tag="ACHY1N_001759"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HFS4044082.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHI
                     DAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     HKAGFEHSELWFQCFNFGSLVALKAEDAA"
     gene            15580..16551
                     /gene="cmoB"
                     /locus_tag="ACHY1N_001760"
     CDS             15580..16551
                     /gene="cmoB"
                     /locus_tag="ACHY1N_001760"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HFS4044083.1"
                     /translation="MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSN
                     AVEFLPEIKPYRLDLLHSVTAESEEPLSTGQIKRIETLMRNLMPWRKGPFSLYGVNID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     EGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRVVDVC
                     VTTTEEQRRTEWMVTESLSDFLDPHDPSKTVEGYPAPKRAVLIARKP"
     gene            complement(16716..19145)
                     /gene="torZ"
                     /locus_tag="ACHY1N_001761"
     CDS             complement(16716..19145)
                     /gene="torZ"
                     /locus_tag="ACHY1N_001761"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310609.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine N-oxide reductase TorZ"
                     /protein_id="HFS4044084.1"
                     /translation="MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRW
                     GAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPA
                     KGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
                     YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQAVVLWGMNPL
                     NTLKIAWSSTDEQGLEYFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVA
                     LMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKSDNTPKSAAWAAEITGVPEAQ
                     IVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYS
                     NGGNPTRVGGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQ
                     TYPNIKMIWWAGGGNFTHHQDTNRLIKAWQKPEMIVVSECYWTAAAKHADIVLPITTS
                     FERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKPGGKEIYTEGKDE
                     MAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYADFRADPVK
                     NALGTPSGKIEIYSKTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLH
                     SQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLVRVWNKRGQILTGAVVTDGIK
                     KGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTGNAPK
                     LTAFDQPAIQA"
     gene            complement(19170..20270)
                     /gene="torY"
                     /locus_tag="ACHY1N_001762"
     CDS             complement(19170..20270)
                     /gene="torY"
                     /locus_tag="ACHY1N_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707761.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HFS4044085.1"
                     /translation="MRGKKRIGLLFLLIAVVVGGGGLLLAQKALHKTSDTAFCLSCHS
                     MSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDS
                     DDKFETHRQEMAETVWKELKATDSATCRSCHSFDAMDIASQSESAQKMHNKAQKGGET
                     CIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKTSRIGELATVNPGTD
                     LTVVDASGKQPIVLLQGYQMQGSENTLYLAAGQRLALATLSEEGIKALTVNGEWQADE
                     YGNQWRQASLQGALTDPALADRKPLWQYAEKLDDTYCAGCHAPIAADHYTVNAWPSIA
                     KGMGARTSMSENELDILTRYFQYNAKDITEKQ"
     gene            complement(20658..21404)
                     /gene="cutC"
                     /locus_tag="ACHY1N_001763"
     CDS             complement(20658..21404)
                     /gene="cutC"
                     /locus_tag="ACHY1N_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025309.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFS4044086.1"
                     /translation="MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLK
                     SVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVD
                     MPRMEKIMAAAGPLAVTFHRAFDMCANPLYTLNNLAELGIARVLTSGQKSDALQGLSK
                     IMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSS
                     DEHADEYSRYIVDGAAVAEMKGIIERHQAK"
     gene            complement(21418..21984)
                     /gene="yecM"
                     /locus_tag="ACHY1N_001764"
     CDS             complement(21418..21984)
                     /gene="yecM"
                     /locus_tag="ACHY1N_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310612.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4044087.1"
                     /translation="MANWQSIDELQDIASDLPRFTHALDELSLRLGLNITPLTADHIS
                     LRCHQNATAERWRRGFEQCGELLSENMINGRPICLFKLHEPVQVAHWQFSIVELPWPG
                     EKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLPNP
                     TLAVTDGKTTIKFHPWSIEEIVASEQSA"
     gene            22200..23933
                     /gene="argS"
                     /locus_tag="ACHY1N_001765"
     CDS             22200..23933
                     /gene="argS"
                     /locus_tag="ACHY1N_001765"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFS4044088.1"
                     /translation="MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALAS
                     DRLGVSTPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
                     DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQ
                     SGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYESLHADRVL
                     YYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKAEINEEQLAAAPVIIREDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            complement(23975..24019)
                     /gene="yecV"
                     /locus_tag="ACHY1N_001766"
     CDS             complement(23975..24019)
                     /gene="yecV"
                     /locus_tag="ACHY1N_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YecV"
                     /protein_id="HFS4044089.1"
                     /translation="MSIFRIHLDGNKKA"
     gene            24110..24598
                     /gene="yecT"
                     /locus_tag="ACHY1N_001767"
     CDS             24110..24598
                     /gene="yecT"
                     /locus_tag="ACHY1N_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416391.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HFS4044090.1"
                     /translation="MFKFLVLTLGIISCQAYAEDTVIVNDHDISAIKDCWQKNSDDDT
                     DINVIKSCLRQEYNLVDAQLNKAYGEAYRYIEQVPRTGVKKPDTEQLNLLKKSQRAWL
                     DFRDKECELILSNEDVQDLSDPYSESEWLSCMIIQTNTRTRQLQLYRNSEDFYPSPLT
                     RG"
     gene            complement(24718..25110)
                     /gene="flhe"
                     /locus_tag="ACHY1N_001768"
     CDS             complement(24718..25110)
                     /gene="flhe"
                     /locus_tag="ACHY1N_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HFS4044091.1"
                     /translation="MRTLLAILLFPLLVQAAGEGMWQASSVGITLNHRGESMSSAPLS
                     TRQPASGLMTLVAWRYQLIGPTPSGLRVRLCSQSRCVELEGQSGTTVAFSGIAAAEPL
                     RFIWEVPGGGRLIPPLKVQRNEVIVNYR"
     gene            complement(25110..27188)
                     /gene="flhA"
                     /locus_tag="ACHY1N_001769"
     CDS             complement(25110..27188)
                     /gene="flhA"
                     /locus_tag="ACHY1N_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HFS4044092.1"
                     /translation="MSNLAAMLRLPANLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NVVGGLLVGVLQHGMSMGHAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVNQLFSNPSVMLLSAAVLGLLGLVPGMPNLVFLLFTAGLLGLAWWIRGREQKA
                     PVEPKPVKMAENNTVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQEMGFLPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLP
                     GEATVDPAFGLNAIWIESALKEQAQIQGYTVVEASTVVATHLNHLISQHAAELFGRQE
                     AQQLLDRVAQEMPKLTEDLVPGVVTLTTLHKVLQNLLDEKVPIRDMRTILETLAEHAP
                     IQSDPHELTAVVRVALGRAITQQWFPGKDEVHVIGLDTPLESLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(27181..28329)
                     /gene="flhB"
                     /locus_tag="ACHY1N_001770"
     CDS             complement(27181..28329)
                     /gene="flhB"
                     /locus_tag="ACHY1N_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhB"
                     /protein_id="HFS4044093.1"
                     /translation="MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSV
                     IWFGGVSLARRLSGMLSAGLHFDHSIINDPNLILGQIILLIREAMLALLPLISGVVLV
                     ALISPVMLGGLVFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKTILVGSVTG
                     FFLWHHWPQMMRLMAESPITAMGNAMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKK
                     LRMSRQDIRDEFKQSEGDPHVKGRIRQMQRAAARRRMMADVPKADVIVNNPTHYSVAL
                     QYDENKMSAPKVVAKGAGLVALRIREIGAENNVPTLEAPPLARALYRHAEIGQQIPGQ
                     LYAAVAEVLAWVWQLKRWRLAGGQRPVQPTHLPVPEALDFINEKPTHE"
     gene            complement(28531..29175)
                     /gene="cheZ"
                     /locus_tag="ACHY1N_001771"
     CDS             complement(28531..29175)
                     /gene="cheZ"
                     /locus_tag="ACHY1N_001771"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0050920 - regulation of chemotaxis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HFS4044094.1"
                     /translation="MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPI
                     DLADARELVTDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQDQVDDLLDSLGF"
     gene            complement(29186..29575)
                     /gene="cheY"
                     /locus_tag="ACHY1N_001772"
     CDS             complement(29186..29575)
                     /gene="cheY"
                     /locus_tag="ACHY1N_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002210873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HFS4044095.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALN
                     KLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEEKLNKIFEKLGM"
     gene            complement(29590..30639)
                     /gene="cheB"
                     /locus_tag="ACHY1N_001773"
     CDS             complement(29590..30639)
                     /gene="cheB"
                     /locus_tag="ACHY1N_001773"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate methylesterase/protein
                     glutamine deamidase"
                     /protein_id="HFS4044096.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGE
                     RVLPGHAYIAPGDRHMELSRSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAV
                     GVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(30642..31502)
                     /gene="cheR"
                     /locus_tag="ACHY1N_001774"
     CDS             complement(30642..31502)
                     /gene="cheR"
                     /locus_tag="ACHY1N_001774"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HFS4044097.1"
                     /translation="MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLAD
                     HKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHH
                     FPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
                     EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHEGLVRVRQELANYVDFAPLNLLEKQY
                     TVPGPFDAIFCRNVMIYFDQNTQQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLR
                     GQTVYALSKD"
     gene            complement(31521..33122)
                     /gene="tap"
                     /locus_tag="ACHY1N_001775"
     CDS             complement(31521..33122)
                     /gene="tap"
                     /locus_tag="ACHY1N_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein IV"
                     /protein_id="HFS4044098.1"
                     /translation="MFNRIRISTTLFLILILCGILQIGSNGMSFWAFRDDLQRLNQVE
                     QSNQQRAALAQTRAVMLQASTALNKAGTLTALSYPADDIKTLMTTARASLTQSTTLFK
                     SFMAMTAGNEHVRALQKETEKSFARWHNDLEHQATWLESNQLSDFLTAPVQGSQNAFD
                     VNFEAWQLEINHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPL
                     AIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGSHEMHIG
                     IAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQ
                     AGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGF
                     AVVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMIDIVSSVTRVND
                     IMGEIASASEEQQRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRV
                     AVFTLEEHEVARHESAQLQIAPVVS"
     gene            complement(33168..34829)
                     /gene="tar"
                     /locus_tag="ACHY1N_001776"
     CDS             complement(33168..34829)
                     /gene="tar"
                     /locus_tag="ACHY1N_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004888 - transmembrane signaling receptor
                     activity [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HFS4044099.1"
                     /translation="MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSN
                     QLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAAT
                     HYKKFKSMAPLPEMVATSRNIDEKYKNYHTALTELIDYLDYGNTGAYFAQPTQGMQNA
                     MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLT
                     PLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIY
                     AGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDT
                     AQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSTFRLAASPLTNKPQTPSRPASEQPPTQPRLRIAEQDPNWETF"
     gene            complement(34974..35477)
                     /gene="cheW"
                     /locus_tag="ACHY1N_001777"
     CDS             complement(34974..35477)
                     /gene="cheW"
                     /locus_tag="ACHY1N_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HFS4044100.1"
                     /translation="MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVV
                     DGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
                     SAASEVA"
     gene            complement(35498..37462)
                     /gene="cheA"
                     /locus_tag="ACHY1N_001778"
     CDS             complement(35498..37462)
                     /gene="cheA"
                     /locus_tag="ACHY1N_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010283911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HFS4044101.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIF
                     RAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQSPR
                     RIILSRLKAGEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEA
                     DQITFETVEVSPKISTPPVLKLAAEQAPTGRVEREKTTRSNESTSIRVAVEKVDQLIN
                     LVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFS
                     RYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKR
                     LAAGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEV
                     AMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGTGTTIRILLPLT
                     LAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIVELWK
                     VFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAAT
                     ILGDGSVALIVDVSALQAINREQRMANTAA"
     gene            complement(37467..38393)
                     /gene="motB"
                     /locus_tag="ACHY1N_001779"
     CDS             complement(37467..38393)
                     /gene="motB"
                     /locus_tag="ACHY1N_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HFS4044102.1"
                     /translation="MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVM
                     WLISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPN
                     IEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPM
                     FRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRA
                     NASRRELMVGGLDSGKVLRVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHE
                     NAESQNEPVSALEKPEVAPQVSVPTMPSAEPR"
     gene            complement(38390..39277)
                     /gene="motA"
                     /locus_tag="ACHY1N_001780"
     CDS             complement(38390..39277)
                     /gene="motA"
                     /locus_tag="ACHY1N_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HFS4044103.1"
                     /translation="MLILLGYLVVLGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGS
                     FIVGNNGKAIKGTLKALPLLFRRSKYTKAMYMDLLALLYRLMAKSRQMGMFSLERDIE
                     NPRESEIFASYPRILADSVMLDFIVDYLRLIISGHMNTFEIEALMDEEIETHESEAEV
                     PANSLALVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLASVLRQKSAETSKMMQCVKVTLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVKNPQQQTTTEEA"
     gene            complement(39404..39982)
                     /gene="flhC"
                     /locus_tag="ACHY1N_001781"
     CDS             complement(39404..39982)
                     /gene="flhC"
                     /locus_tag="ACHY1N_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045893 - positive regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:1902208 - regulation of bacterial-type
                     flagellum assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HFS4044104.1"
                     /translation="MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLY
                     LEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV"
     gene            complement(39985..40335)
                     /gene="flhD"
                     /locus_tag="ACHY1N_001782"
     CDS             complement(39985..40335)
                     /gene="flhD"
                     /locus_tag="ACHY1N_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416406.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045893 - positive regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:1902208 - regulation of bacterial-type
                     flagellum assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HFS4044105.1"
                     /translation="MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMAT
                     TLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLN
                     DVNQPEEALRKKRA"
     gene            41115..41543
                     /gene="uspC"
                     /locus_tag="ACHY1N_001783"
     CDS             41115..41543
                     /gene="uspC"
                     /locus_tag="ACHY1N_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HFS4044106.1"
                     /translation="MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPE
                     MYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCHKHH
                     FDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD"
     gene            complement(41550..42974)
                     /gene="otsA"
                     /locus_tag="ACHY1N_001784"
     CDS             complement(41550..42974)
                     /gene="otsA"
                     /locus_tag="ACHY1N_001784"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003825 - alpha,alpha-trehalose-phosphate
                     synthase (UDP-forming) activity [Evidence IEA];
                     GO_process: GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HFS4044107.1"
                     /translation="MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSG
                     ETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPA
                     WDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPT
                     PEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKA
                     FRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLA
                     YEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLY
                     YLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAA
                     NELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISD
                     LKQIVPRSAESQQRDKVATFPKLA"
     gene            complement(42949..43749)
                     /gene="otsB"
                     /locus_tag="ACHY1N_001785"
     CDS             complement(42949..43749)
                     /gene="otsB"
                     /locus_tag="ACHY1N_001785"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004805 - trehalose-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HFS4044108.1"
                     /translation="MTEPLTETPELSAKYAWFFDLDGTLAEIKPHPDQVVVPDNILQG
                     LQLLATASDGALALISGRSMVELDALAKPYRFPLAGVHGAERRDINGKTHIVHLPDAI
                     ARDISVQLHTVIAQYPGAELEAKGMAFALHYRQAPQHEDALMTLAQRITQIWPQMALQ
                     QGKCVVEIKPRGTSKGEAIAAFMQEAPFIGRTPVFLGDDLTDESGFAVVNRLGGMSVK
                     IGTGATQASWRLAGVPDVWSWLEMITTALQQKRENNRSDDYESFSRSI"
     gene            complement(43916..44902)
                     /gene="araH"
                     /locus_tag="ACHY1N_001786"
     CDS             complement(43916..44902)
                     /gene="araH"
                     /locus_tag="ACHY1N_001786"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter permease AraH"
                     /protein_id="HFS4044109.1"
                     /translation="MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPN
                     FATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESL
                     WIGVAAGLLLGILCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
                     SFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVV
                     RTKIIIFVLSGLVSAIAGIILASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKI
                     SYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYKQKAKRTV"
     gene            complement(44917..46431)
                     /gene="araG"
                     /locus_tag="ACHY1N_001787"
     CDS             complement(44917..46431)
                     /gene="araG"
                     /locus_tag="ACHY1N_001787"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter ATP-binding protein
                     AraG"
                     /protein_id="HFS4044110.1"
                     /translation="MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGA
                     GKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAEN
                     IYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALAR
                     NAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKD
                     GRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPIS
                     LAVRSGEIVGLFGLVGAGRSELMKGLFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMM
                     LCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPG
                     AEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGV
                     AVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA"
     gene            complement(46501..47490)
                     /gene="araF"
                     /locus_tag="ACHY1N_001788"
     CDS             complement(46501..47490)
                     /gene="araF"
                     /locus_tag="ACHY1N_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter substrate-binding
                     protein AraF"
                     /protein_id="HFS4044111.1"
                     /translation="MHKFTKALAAIGLAAVMSQSAMAENLKLGFLVKQPEEPWFQTEW
                     KFADKAGKDLGFEVIKIAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKAR
                     GYDMEVIAVDDQFVNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAV
                     MEITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPE
                     VKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLL
                     PSPDVHGYKSSEMLYNWVAKDVEPPKFTEVTDVVLITRDNFKEELEKKGLGGK"
     gene            48287..48790
                     /gene="ftnB"
                     /locus_tag="ACHY1N_001789"
     CDS             48287..48790
                     /gene="ftnB"
                     /locus_tag="ACHY1N_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HFS4044112.1"
                     /translation="MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLR
                     AQAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKLNSLEELFQKTMEEYEQRSSTLA
                     QLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLN
                     VVSHQLH"
     gene            complement(48869..49120)
                     /gene="yecJ"
                     /locus_tag="ACHY1N_001790"
     CDS             complement(48869..49120)
                     /gene="yecJ"
                     /locus_tag="ACHY1N_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2766 family protein YecJ"
                     /protein_id="HFS4044113.1"
                     /translation="MSQPLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQ
                     LKNIDFTNHPAAADPVTMRAIQKAIALIELKFTPQGESH"
     gene            complement(49234..49320)
                     /gene="azuC"
                     /locus_tag="ACHY1N_001791"
     CDS             complement(49234..49320)
                     /gene="azuC"
                     /locus_tag="ACHY1N_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein AzuC"
                     /protein_id="HFS4044114.1"
                     /translation="MKLRKILKSMFNNYCKTFKDVPPGNMFR"
     gene            49583..49906
                     /gene="yecR"
                     /locus_tag="ACHY1N_001792"
     CDS             49583..49906
                     /gene="yecR"
                     /locus_tag="ACHY1N_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecR-like lipofamily protein"
                     /protein_id="HFS4044115.1"
                     /translation="MRLLILTLSLITLAGCTVTRQAHVSEVDAATGIVRLVYDQAFLQ
                     HAHTDRYVSRGIADRACQQEGYTHAVPFGQPVGNCSLFAGSLCLNTEFTLSYQCHHSA
                     FPVFL"
     gene            50077..50574
                     /gene="ftnA"
                     /locus_tag="ACHY1N_001793"
     CDS             50077..50574
                     /gene="ftnA"
                     /locus_tag="ACHY1N_001793"
                     /EC_number="1.16.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006879 - intracellular iron ion
                     homeostasis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HFS4044116.1"
                     /translation="MLKPEMIEKLNEQMNLELYSSLLYQQMSAWCSYHTFEGAAAFLR
                     RHAQEEMTHMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQKIN
                     ELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGLYFIDKELST
                     LDTQN"
     gene            complement(50612..50851)
                     /gene="yecH"
                     /locus_tag="ACHY1N_001794"
     CDS             complement(50612..50851)
                     /gene="yecH"
                     /locus_tag="ACHY1N_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family metal-binding protein"
                     /protein_id="HFS4044117.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHASLEAAIKARFGEQARFHTCSA
                     EGMTAGELVAFLAAKGKFIPSEEGFSTDQSKICRH"
     gene            51042..52253
                     /gene="tyrP"
                     /locus_tag="ACHY1N_001795"
     CDS             51042..52253
                     /gene="tyrP"
                     /locus_tag="ACHY1N_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015173 - aromatic amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015801 - aromatic amino acid transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HFS4044118.1"
                     /translation="MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGA
                     GELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVM
                     LVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNVRKLRWVF
                     ITGSAIPLVAYIFWQVATLGSIDSTTFMGLLANHAGLNGLLQALREMVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQF
                     LIAAGLLPEVG"
     gene            complement(52315..52980)
                     /gene="yecA"
                     /locus_tag="ACHY1N_001796"
     CDS             complement(52315..52980)
                     /gene="yecA"
                     /locus_tag="ACHY1N_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YecA"
                     /protein_id="HFS4044119.1"
                     /translation="MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSP
                     QEIEPEQWLVAVWGGADYVPRWASEKEMTRFMNLAFQHMADTAERLNEFPEQFEPLFG
                     LREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMS
                     PEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQC
                     CLH"
     gene            complement(53337..54338)
                     /locus_tag="ACHY1N_001797"
     CDS             complement(53337..54338)
                     /locus_tag="ACHY1N_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4044120.1"
                     /translation="MSVRKIPSGKWLCECYPYGASGKRIRKQFATKSEALSYERRLMN
                     SRVGDEFQDGSGPRLSELIARWFEMYGKTLSSGAERKVKLEAICSRLGDPFASQFDKN
                     MFATYRERRLSGEWNPKGKKKLSEATVNREQSYLHAVFAELKRLGEWSGENPLTGIRK
                     FREEEKELAFLYVDEIERLLIACDESRNKDLGVVVRIGLATGARWSEAEGLKQSQVLP
                     GRITFVKTKGKKNRTVPISPQLQAMLPKKRGALFSPCYEAFDAAIKRAKIELPDGQLT
                     HVLRHTFASHFMMRGGNILVLQKILGHSDIKMTMRYAHFAPGHLEAAVELNPFDNRG"
     gene            complement(54344..54691)
                     /locus_tag="ACHY1N_001798"
     CDS             complement(54344..54691)
                     /locus_tag="ACHY1N_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2511 domain-containing protein"
                     /protein_id="HFS4044121.1"
                     /translation="MKVKKVQLLVTFLSMFSFSAVAMPFKTIERESFNGVWPFNSDEV
                     QLQCLDGNPYVMNFDDNKLYALTGLARIKGKTFGALPLDNNNPFWLDNDAAPGLKKSL
                     GDVTKAAFDLCDK"
     gene            complement(54721..55371)
                     /locus_tag="ACHY1N_001799"
     CDS             complement(54721..55371)
                     /locus_tag="ACHY1N_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044122.1"
                     /translation="MAVNSNGSNNRVAGRDFHEKNIQIERYDGSHTVNIAIPSNNDDD
                     DRPLLKAQRKELNSLVAAIAEASNTEAFIIWQKVHAEIGVAGIDDMTVNQYKTAESFL
                     HAMLERCKDHDACKALVSLLLRNSEDCGLRQKLLRYCHINFGTGRLNDLTRSQLQSAL
                     SWLEQQSASSHTESSTLPEVRLRASELIRLYPKEIIFFICVGVLVGGVISRAFFNL"
     gene            complement(55387..55791)
                     /locus_tag="ACHY1N_001800"
     CDS             complement(55387..55791)
                     /locus_tag="ACHY1N_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4044123.1"
                     /translation="MKNDIGQRLREERERLGLSQVAMSDIGGVKKLTQLRYEKGDSFP
                     DAAYLAALSRFGLDVQYVVLGIHSPETYNDDEQELITRFRAASLDVKNAVIGALKGAI
                     SEKETQPSGRELNISGGNNRIAGRDYNETKGR"
     gene            complement(55881..56018)
                     /locus_tag="ACHY1N_001801"
     CDS             complement(55881..56018)
                     /locus_tag="ACHY1N_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_305354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044124.1"
                     /translation="MRAMLEDERCSLAAISSMTARSSRDSRSASLGPVAVLRGMRDLV
                     S"
     gene            56090..56293
                     /locus_tag="ACHY1N_001802"
     CDS             56090..56293
                     /locus_tag="ACHY1N_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFS4044125.1"
                     /translation="MSGITININVNAPYVSLQKYAEITGIPLNTCKKMLADGRIIIRP
                     KRAKMEKPEVNLVAMLKDALANS"
     gene            56315..56665
                     /locus_tag="ACHY1N_001803"
     CDS             56315..56665
                     /locus_tag="ACHY1N_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4761 family protein"
                     /protein_id="HFS4044126.1"
                     /translation="MKKNANNPYSKFRNGVERHVHHVATSASRSNSRYNLNETHATPD
                     GHAVKQIGEHAWLIEKAGIVVHKCPRNPFTGNRIFALNCGDNHFGQDFTLYEALRTVD
                     RLLRGQSFIKQADL"
     gene            56676..56954
                     /locus_tag="ACHY1N_001804"
     CDS             56676..56954
                     /locus_tag="ACHY1N_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044127.1"
                     /translation="MTKEHAQGVFIRFIDFRGELLLRASAIDGVVPSEKNAATYVYLN
                     GTRLTVELPYQTVHEIISEAEKARQVNGDKPYIEIICMDSEAEIQKAD"
     gene            56966..57208
                     /locus_tag="ACHY1N_001805"
     CDS             56966..57208
                     /locus_tag="ACHY1N_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4754 family protein"
                     /protein_id="HFS4044128.1"
                     /translation="MDKEYKTLINKALERFYFRLSASGVHAERAARDSLTRAIRSLYD
                     VAFYADDLDALNELSELICAAECGEHIEPYKLGNIA"
     gene            57205..57318
                     /locus_tag="ACHY1N_001806"
     CDS             57205..57318
                     /locus_tag="ACHY1N_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044129.1"
                     /translation="MSIFISWLVLIISVACAIGIMRIINSVKKIERFFSDE"
     gene            57412..57822
                     /locus_tag="ACHY1N_001807"
     CDS             57412..57822
                     /locus_tag="ACHY1N_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001376666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044130.1"
                     /translation="MHAKEEGIIRALKEISKMESEVAKKAVANAHMDVATHTMIVAKV
                     TAEAAKIIEEQGVELALLKTKPVTGLDLSDTGRLIYTIGSEPQRYTIIAGLQNKYLIT
                     PHPIRESTLLTNLRLIERSQVAFIDDARHTVFNA"
     gene            57846..58049
                     /locus_tag="ACHY1N_001808"
     CDS             57846..58049
                     /locus_tag="ACHY1N_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044131.1"
                     /translation="MAIKHFPVVRFTSRGREYEVDERLITTIDKHRSEKDAHHIYLTD
                     GTYFCATNVARVNLIRQVQEPRR"
     gene            58046..58312
                     /locus_tag="ACHY1N_001809"
     CDS             58046..58312
                     /locus_tag="ACHY1N_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4044132.1"
                     /translation="MTILDYIATHPGCSGGEIAAALNTPTTAINAELRQLWRGGLVIR
                     TNRSTGGRARKTGGQASYHVNPMPFGCSNPLTHMFNQLLKEART"
     gene            58309..58608
                     /locus_tag="ACHY1N_001810"
     CDS             58309..58608
                     /locus_tag="ACHY1N_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044133.1"
                     /translation="MSTINHQKLRELAFALQRMATPQKLLAFRAMLSPSAVLALLDEL
                     EHARTTAPAIRLTLHHEIADFCATLEAPGEPETPEAIQQELLQRIDKVFDFFLNQ"
     gene            58931..59143
                     /locus_tag="ACHY1N_001811"
     CDS             58931..59143
                     /locus_tag="ACHY1N_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="derepression protein"
                     /protein_id="HFS4044134.1"
                     /translation="MANRKQQRAYAARRHIQTEINRRLFRASRVAQIMHINMLHERSH
                     ALSNIYSASVFSYLADDLRELQQLFQ"
     gene            59234..59623
                     /locus_tag="ACHY1N_001812"
     CDS             59234..59623
                     /locus_tag="ACHY1N_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001534315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase"
                     /protein_id="HFS4044135.1"
                     /translation="MIDAHDFTRWVRTQDTRLAPVLQGLFDLYIRGRDNRARTTKPEN
                     ADTLYFTVDDCYRVDFTPHGLALHCLTPHGESLLAYYDSPASVFAAMLAHRTAGGCAS
                     LSEYTAEFNRLSALFSQEWQRVTGYQP"
     gene            59620..62460
                     /locus_tag="ACHY1N_001813"
     CDS             59620..62460
                     /locus_tag="ACHY1N_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HFS4044136.1"
                     /translation="MSEFAWSWNEPRPAIDPARFTEHRQETETDLQRAIRYYLEADKK
                     AREEQEAKEEAFFAQSAMGKKLMASLEEAGQREKLAQSIISKRRATEQDPVARAFATL
                     KALPVYLREPLSRHLSFLRKKQEADRQKGKKSWQAERYARGTLRKIFERLDRTDSRWL
                     TPGYRSLAGRERLDDLLYLPQLNKHQIQTLATMTAAMFSSTFEKLCDGFGATDGELTM
                     DVTLKAYQMLARMALHLHAMPPHYDALTTDKDRRNEPDTELLPGAILRLTCAEWWKRK
                     LWLLRCEWREEQLRAACLVSRKTSPYLSQDALSEFRAQREKTRDFLKSFMLENEDGFT
                     IDLETVYYAGVSNPVHRKAEMMATMKGLELLAEARGDKAVFLTVTCPSKYHATTENGH
                     PNPKWNGATMRDSSDYLVNTFFAAVRKKLNRDGLRWYGIRTVEPHHDGTVHWHMMVFA
                     HPEEIDTIVSHTRDIAIQEDRHELGDDITPRFKAEYVDGSKGTPTSYIATYIGKNLDS
                     RAVDGIDPKTGKPRVDHETGKSMAESVERAIGWARLHRVRQFQFFGIPSRQVWRELRR
                     LASQMARNPEGPQRLKDDAMDAVLAAADAGCFATYIEKQGGVLVPRKDYLIRTAYDLA
                     DELNDYGEQSVQIYGIWSPLIGESSRVCTHPDNWKLVRRKPEAEDSARENGFDLQGGP
                     AAPWTRGNNCPRVQETDNNGTEQPEERPAPWPQLPDGVDVDEWVRSLKRHERRALMRS
                     LRDKQAKNSSDEMQSWTQSRKQQRPLPDNHELLAREWRESAESLGLHIGEQQMQHLLR
                     GGSLYVDGSIIAPQGFEIVRKPDTRPDSRITQLWQRLSRNHGVSSTEIRHNPVASYLA
                     QLGASDPEAATRLASTLQQDQNTMKTPVTVLSDMLRAIRDAEHAQRISETTERARRKA
                     DLLRGGLTSGNKKQTETGFTNPVNEQKTRRDI"
     gene            62537..63496
                     /locus_tag="ACHY1N_001814"
     CDS             62537..63496
                     /locus_tag="ACHY1N_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HFS4044137.1"
                     /translation="MKICIDDGSTNIKLAWTENSERRNAISPNSFKSEWSAPFGGSQP
                     ANYMLDGVRYGFDPVSDRFVQTTDTQYQYSDVNVIAIHHALVKSGITPQEVDVVVTLP
                     LSEYFDTNAQPDMANINRKKANVMRPVEYQNGEAFTIRNVRVMPESIPAGFKALADMS
                     PFESLLIVDLGGTTLDVAKVQGQLAGISQVFCDPHVGVSLMADAVLSVMATNGMRTSH
                     HIANTIIEHRHDEAWLRQHIHNDAHYASLMAVIREKEETLKQRVIRALAGFSGYGRVM
                     VVGGGAEIVAPAIREACGVNATFIADGVPQFALVNGLYAMDKE"
BASE COUNT        16177 a        16515 c        14883 g        15945 t
ORIGIN      
        1 ttcgcgtgaa aggtaagtat tctgcgcaat ctccccgact gtcgccgggt cggtaacgct
       61 taattcatta aacaccactc tggcggtttc tgtcatatcc tgctgtttta gcatgtcttt
      121 tttccctttt ggttaacgtg acataccaat aactcttgtc caaaaagcca gcaagcagaa
      181 agaccggtat tcgcaaccac cagcgcatta acgccccgtg ccgtttttca gtcataaaaa
      241 aacccgcaaa aagcgggctc tttcaaatgt ccatgtctgc tattcgcctc gcggtacagc
      301 tttgcgaagc gtaccggaat tgaagcagtt tttacgtcaa aaagcaataa cttttttctc
      361 tataccaaaa gccataacca ttggtttgta caaaataaat tctgccacct ttagccaatg
      421 ctcaatgcgc ctttcacagg ttcttaaact ccattccgga tgtgcatcat tcagcagttc
      481 agccattttg cgcttagtca tcccccgccc caaataacgc tgactcagaa cattgaacaa
      541 cccgggataa cctgccagta cttcaccaat aaccctgtcg attattaacg cctctgaatc
      601 ggtacaatgt gccagccagc ttttttgatt gccgttgatc atatcccgca aaaaagcctc
      661 aagttcaggt ttgtccagac ccgctctttt catcctccgg agcgcctcgt taattgccgt
      721 ttttgtcagc tttttagagg tcagtaattg gttgaacata tttcccgtct taccgtcgcc
      781 aatatacgac caacgccccc acatacgcag tttcccctgg atccagacac tttccagcgt
      841 tttcaggcgc aaatgctcac cgcttttgcc tgtaatttcc gggtatatca tatttatgct
      901 cactcacttt caattttgta aatctgcaca cccaaccgac caccagaaac gagctgaccg
      961 cgcacaatat taatttcgtc aaactgctcg tcgtctatga gcaatccggc atgcgtcagc
     1021 gcatccagtg gtgctttcag gatattgtcc aggtcacgac ggcgcttatc cggtggctct
     1081 gcaataatct ttatcgccag ccttccggac aggtttaatt tcagccgctg ctggcgaaca
     1141 attagcgcca catcacggcg ataacgcttt ccggcctccg agatgaaata cgtattgcca
     1201 tgacgtcgcc agtaagtatt caccgtcggc ggataaggta aaataaactc atggcgcatc
     1261 agcgcagcac ctcctgcacc attttttcaa actttccaac tttggtttcc agctccgcca
     1321 cacaatccac cagctcatcc actgcttttt gtgcgcgatg tttcgcctgc atcagttccc
     1381 tgagcgctgg caccatatcc cgacgaatgg catcttttgt tacacctgtt ttttccagtt
     1441 gttccgcctg tcgcaacatt tcctgcgcct gtttgcgtaa ttgttcaggg gtaaaagtca
     1501 ttgtctggtt gttcaaaaga aacgctccat cttactgctg tcagttcgtt tgttgctgta
     1561 tctgcgcggc tggggctgct gcattggggt ggaaagaatc tgtgcgcttt cctgatccac
     1621 aggcagaaaa tgtccgttat aaaaacgccg gtaaatcgtc cccagagaac cgttacgttg
     1681 tttcgtgata ttgatttctg ctatgcccct ggcctgcgta tccgggttgt atacttcatc
     1741 cctgtaaagc atcagaataa tgtcagcatc cgcctctatt tctccggaat ttttcaggtc
     1801 tgagttcata ggtcgtttat tgggtctgga ctccacagcg cgggaaagtt ggctcagcgc
     1861 aaccaccggt aatccgccga attttgccag gcctttaagc ccttttgata tttcccccac
     1921 ggcaaggtca tggcggcctg tggttcgggt ttttatcaac ccgagataat caaccaccac
     1981 cagcgccgtt tccgggtgtt taatcagatg gtgtttcgtt gttgcgcata tctcatcaat
     2041 cgtcaggttc gcctggtcca ccatccagat attacgtcct gtcattcgtc ccacaccctg
     2101 tgagaaacgc gcccagtctt catcttcaaa acgggcaaca gatttaagac gggataccgg
     2161 cattccccct gctgctgaca ccatacgttc accaatctgg atgttcgcca tctccatggt
     2221 gaacagaagc acgccatgct cctgctctgt caccttgtcg atgatatcca gcgccagttc
     2281 ggttttcccc atagaagggc gagccgcaat aaataccagg tcaccgggtt ccatgccgcc
     2341 tgtttttgcg tccagttcat caataccggt catcaacgtc ctggatttct ccagcccctg
     2401 attccggcat tcaacacgct caaccacttc cggaagcaca tcatcaatat gcacaggctg
     2461 tatgacgccc tttccggttg ataatgagac aatcatgttc tgcgcatcct tcagggcatc
     2521 ttcagctgcg tcacaggtat tcgcatcacg taatttctgt aacgcctcat tcagtgtttt
     2581 ttctgcatcg cgcagtgctg cattgcgccg caacgccgta acatagtgct ccagtgacga
     2641 cttcacccag gttttgcgcc cggtgtcagt aatcaccggg gcaagttccg gcatctcatt
     2701 acacagcagc acagggtcaa tcactccaga aacacgtgcc tgtctgcaga tgcctctgta
     2761 gatatcccgg tacggtcgaa cagaaaaaac ctccgccggt agtgtggcca gaatatccat
     2821 cacttccgga tcagcaccac gcagaaaaaa cgcgccaatc actgcacctt ccaggtcatc
     2881 attacgccac accggatttg tcgggtttgt catgctgcca cacctctgat atgcgcacgg
     2941 tagctttccc aaccaaacac caggcagtta cgcccaccat cagtaacgcg atccacaatc
     3001 cgttcaccaa tggactcctt gagttgttca aacgtcaggt tgctgatcaa aattgtcggt
     3061 aaaacgcttt cgtaacgcgc atttatgatt tcctgcagga tggttatctc cgcaggcgta
     3121 ccgaactgca caccaacctc atcgataata agcaggtcca gcgatacaaa atggtcaata
     3181 atttcatctt cagtgcgttc agaattgtga cgccaggtat ttttcacagc gcgggtcagt
     3241 cgcataacat ccgtaatttc gacggtcgcc aggtggtggc gaataatatt ttttgccatt
     3301 gatacagcca ggtgattttt cccggtaccg caattgccaa tcatgatcat gctggtgcct
     3361 gcagcgagac atttcttcca ggaagcggcg tagcgctgac aggcttcaag gtttttctgt
     3421 gcgtcagtat tcaccgcctg ataattatca aactcacaat cctggaaccg gcgggcaata
     3481 gcggcctgat cgagtaattc acgaaccttc agggcgcgta attcgtcata cacgcagtcc
     3541 agctcctcac tgaggcagga aaggcaaccg gacacccgtt tgacagcttt ccctcttaca
     3601 tccgggcctg tcagcacata gcgtgtgtat tttccgtgtt tcccgcagga caccgtctca
     3661 gtgctttgca cccaatgctc acagcgccac ggacgctttc cgccacggac aaatgccagc
     3721 tcctcttcca ggtctgcctt gcggttaagt aactgcgctt tgtcgtgttg catgtattgt
     3781 ttgttcagga aattagtcat tttcaccccc cacaaaatca ccagttgaag ttcgttgagc
     3841 cgtagtcctg ttcactgaat cccgagatcg ggaggctttt gccacgccca cctccggggg
     3901 ctgctggctg ttgccaggat tcgtcaaagt gccgatcggg gccaaagaac gtcgcagcct
     3961 gcttcacgaa ctgtgtgccg gtatttcctg tagcacgtac ccaggcggca taccgcttca
     4021 cgccatcaag catggtctcc ggttttattc cctccctgat acgggctttc caggctttga
     4081 aggctgctga cttggaatta ccaccagcac gtttggggta ttcctgccag gcctgttcaa
     4141 attctggtga atattcctgt cgggcagaac gcgctggtgc agacgcgtca gcggatgcgc
     4201 caatagtgtt tttactctct gtagtattct ctgaagtaat ctctgttgta ttctctgtaa
     4261 gatcgaaatt ggttttccct tctccgcggc gaggggtttc ccgtgtccgc ggtgaaggct
     4321 ttccctcctc cgcgaaatcg ggttttacag ttccccgaaa acgggtttcc ccatttcggg
     4381 aaaactgatt gttttcattg ataatttcat taaggcgctc acaatctata cggtagaaca
     4441 ttttgtgctc aagacgcttg ttggtttcaa ccaaaatgcc tctggacaca agatgcttac
     4501 gcgctacagc ctgttgttca aatgtaagtc cggtttcgtg ttgtatctct tcacgcgttt
     4561 tatgtacgcc ttccgctgca tgtgctttat cctgccagta aaaaatctga ccaaagaaaa
     4621 taacagcgtg cggacttccc atgtatttaa cgagcccagg gtaataagca accggatgcc
     4681 caaaatcgag cagaagatca gacggacgca tagccacctc ccaggcgctt aaacattttc
     4741 ccggactgaa aagccaccag cggataactc cgggtatgag tacgtccctg aacctggcag
     4801 acaaccttct ggctttctgt attgactagg caaacccgca gaacgtggcc gttgctggtg
     4861 gtgaaccact gccccacacg ggggcaacgg ttgtatcggt gatacaggga attaacgatg
     4921 tagcggatca tggacgcacc tccgccgtag ttacgtattt aaccgggcta cctttcattg
     4981 agatggtttc acacatctct gccgctttca gttccgccgt ttttctggat ttatagcgac
     5041 ggtgccagac agatacatcc gtgcgaactg atacatcgtt tctgtattcc gtagtggaga
     5101 tgatgatttc gtaactaatc atgggcgcac ctcccattga ttacggtgga aatcggtgtg
     5161 attcagaccg gtttcagctt catggaatac ttcaatgcag ctctcgtagt accgcattgt
     5221 gcgcagactt aacccaagct gaagcatcat cagaccatca agggttatgt aataaccacg
     5281 caaagagtca ccatagaggt gataagtgca cggtatgaaa ttgcgggtaa aaaattcgcg
     5341 cgaacagttc agatactcga ttttatcgac gatgttctgg tgcattcgct taaagtggca
     5401 ggcgacatgc aaagagaaaa taacggcctt gccgttgacg ctctcaattt tgaggaatga
     5461 gtgggttggg actgtagcca tgatggcagc ctccttgatc ggtgaaatac ttccaccacc
     5521 ggaaacgcca atttcgctgg tggtgaactg aacggggttg gcgtaaccgg tgatcaagga
     5581 aaccggcgca tctttcgatg cccccgccca gcccaccata actttgatgt gagcaaatgc
     5641 ggacgataaa aaagacgctg gcgcgtcata tatcgccttg atcaattcca ggacgccaat
     5701 cccggcaccc gctttataag gtgcagagac agtgtaacgt cccgaaattg cagaatcaat
     5761 atttggtctt gaaatgatca tatagctgct gatatcttta gaactgttct tggatgtttc
     5821 ggagccgttt tatgcgaaac agctccccgt tattgatgtt gagtgagccg ggttactccc
     5881 ggcttttttt caccgctgcc aaccaataac ctgaaataac cccattttcg ggtgatacca
     5941 gcgagtccct cgcggttctg cttcctccat aacccgataa aaagcagcca taaacggttc
     6001 cacagcaaca attgcgcgac gtgacaacaa tccgtccgac gtcatgaact cgtgggtgtc
     6061 tgtaggaatt tgataagcgt tcaccagatt gcagcattta tcatctgaca aaccggtttt
     6121 cgctttcagt tggcgatatc cggcatagcc ctcacgaatg gtgccctttt tgatttgctc
     6181 gactgtttcg gcaacatggc tgactttttc ttccacctga gtgatccgtt tctgctgacg
     6241 aacggcttca agagccatcg cagcaaccat ttcgatttcg ctcattggct tacggatctg
     6301 ttcttccagt tcgcgccagc gatctaccag gcgggcagtg aattcagggc agagctgtgc
     6361 gacgacaatg atgctgtcgc gtttaccttg ttctccttca aacaggtaat gctcatattg
     6421 aactttaaaa cctaagttat tgattttctc ggaaacagcc attggcggtt tccggatgat
     6481 gtttttagca accaggcgtt cgatactacg tttaacatct gagtgctgac tacccaccaa
     6541 ctctgcgatc tcaacgctgg tcatggatgc ttttccgtta aaaattgcgg tgttcactac
     6601 catctccttg tggataaatt cttttaagat tccgcacatt cgtacttatt ggtgccgaac
     6661 cttccttcag ttatcctttt gatctctata aacaaaagaa ccaaaggagg ttcgacatga
     6721 aagttcaggc cgttggttta ttctggtttc gcgatgcgat tcagtatcat gagctcaaaa
     6781 atatttttac tgatgctgat gtgctctccg acagttacac cgagtggaag cacgacgctg
     6841 aaaaattgat taagcgtgtc gaaagaggcg ggcaacgagt tattaaagtt gaagcggata
     6901 cagccgagtt catcgcctgg tgtacaagcg aaggcatcgg aatcaatgcc gaaggtagaa
     6961 tgcagttcgc atcctttaag gcttaccaac aacttctcag cgaacgctaa tgtgattggg
     7021 gcaatcgaaa tggttgcccc atcgtattta atagttattt tttcgctcat atcaccacca
     7081 tcacttccca tcttccgtgt gcgctaggct tggatttgaa attttgcgta acgaatcagg
     7141 aactccatct tcagggtgag gataaagatc tggccttaag ccatgtggtg tgaccttcca
     7201 tgcaactact tcacatacgc gtaaaacaaa acgagcagga attgtgtttt ttgaaaacca
     7261 ttgattcacc gcttgcggcg tcacaccaag atttcgcgct atggcatttt gcgcaattaa
     7321 tgtacgaagt ttgtcgtaat catttccttt cataacaaag caccaacatt aactttataa
     7381 atcaagaata catcaagttt aaattaacat gcaagttgca aaaggatcga atacactaaa
     7441 atcaagtaaa gatttatcct tgtaaagaaa cccacaggat ttggtcatga agaacgtcaa
     7501 aaacacggaa aatcgaatag ccgcgatgct gaaagcaaaa ggatggactc aggctcaact
     7561 ggcccgcaag ttaggtgtga gtgcgcaatc agtgcagtac tggacaacag gaaaaacatt
     7621 tccacgaagt gataagctcg cgcatttatc agagattagc ggttatccac aatcctggtt
     7681 cttaggcgaa gactcctcac caaccttttc ctcgcaagag aaacaccaga caagaacaga
     7741 tagcgtcgtg tttaatgtcc ttgatgttga gtttagttgc ggtgatggaa ctcatgtccg
     7801 tggtgacttg atagatgtag tgcgctcaat agaacttgat cctgaatatg cccgacgtct
     7861 tgttggaaat cgggcattca aaaatataga aataggtaac gccagaggag acagtatggc
     7921 tcccacaatc tcacctggcg accttctttt tctcgataag acagtaactt attttgatgg
     7981 cgatggcatt tatgcatttt gttttgatgg agaatgctac gtgaaaagac ttcaaaaaat
     8041 tggaagtaaa atcatggtgt tatctgataa ccccaattat caaccatgga gcatcgaaaa
     8101 agaggggtta gctctgcttt atatccagtc taaagtgatc tcatcaatac cattcaatat
     8161 aaacagattt ggttagtctt tgattttaac gggctttgcc cgttttttct gcctgaaaca
     8221 cacgatatca attttttctt gacagcctat ttctcaaagc ataatatcgc accatcaatt
     8281 ataacttgat ttaattcaat ttaaaattgt tggtggatat atgaagacac taaacgcaac
     8341 tccagaaaca actaatttta tcaactgtgg ctgtgtttcg cttaagggct tagaacttga
     8401 ttcctttgca ttaaatattg caaatttgct aagtgctgta cgcacattcc atcttctgga
     8461 ttgtgctcgc tcaaaggaac tgggcattga ggtaatggaa tttatccatg aatatgctct
     8521 atctgcggct tctcctgcac aacaaaaaca atccttccct gaaagctggc tggttaacct
     8581 tcgcacccaa cgcgaagcct gcggcttaac aaccgccgaa ctcgccaggc tgctcgatct
     8641 cgatgaagaa attatcatcc agtgggagag tggagagtac gagccaacca tcagcatgct
     8701 tacccccctg gcaaacgtcc tgggatgcga tccgctttct ctgctgagtg aaaaaaacag
     8761 cgagtcagtt attcgcgtaa atgcgcctga agtccatgtg gaaaatattg gtgcgcgcat
     8821 caaaagcgcc cgtaaaaaac tgggcttaac agaagcagac ctggcacgca tgattcacac
     8881 ctacagcgac cccataaacg actgggaatg cggcacctgt gaagttcctg ctgatcagat
     8941 agtaccactg gccagtgcgc ttaattgtga cctgatgtgg ttgttaacgg gaaaatcaga
     9001 agcaaaggag tagcaacaat gactggcaat atccatgata agtatgaagg cttatgccta
     9061 gcaccggatt cctttgcaaa caatatccat aatttattat gcgcagttat cgtactacaa
     9121 atgtcagaca acgacgcaat aaaaagaaca ggtgatgaag ttcttgaatt tgcacgttgc
     9181 tatgctgaag cagcatctga aaaagaacta tccagttaaa taaaacaagt tatctccgaa
     9241 taatatatta cggcttaatc gccggggatt atcacacact taatccactg gaggcattat
     9301 tatgactttt ataaaacata aggcatcaca caaaacggcc tgtcttattg cacaacacgg
     9361 taaaaattac atgcatattg cctgcttgtt tctgcgtaaa gcatacggga aataacaaat
     9421 ggcatatgaa cccattaata catatcgtcg ccgtatagct gttgcagcac tccatcgaat
     9481 aaaacgtaaa acaggtggta atctgcttat tgttgacctt ccggatggga gcattacgac
     9541 catagaaata acagaacagt ttataaacca gttgctgttg cgctttgaag gtattacccg
     9601 tggtgaattg ggtcgagtgg agggtgaaac agaattccga actgcatacc agaatgctat
     9661 cgggattaat caacatactg aataccaggc tgaaaccgga aagttaatta tagacaacct
     9721 tttacaagag gttattgatt acgcgaaaga aaaatatatc agcggaggaa ttaactgatg
     9781 gctaatttat cccctgtatc tgttgtgcac gaaaaagtgc agatcgttat gacaattgaa
     9841 aatggccagg taacagatgt ctgcaaagtc cgcgatggag agctgattgc cagcatggat
     9901 acattcatat ggctggcaga aagagcgggg tatcagataa cagcacctgc tcaggaggaa
     9961 accagtgaca ttaacagcaa cgcgaattcc tgagtgggtc caccagcagg cgttgctggt
    10021 cctgcggcgg tacagatgcc gacgtatatt cccgcatcgg atacagcgca acggatatct
    10081 cagtctgaag gttaaccgtc gctggcggct gttatcgaaa gacgacggcc ggaactggga
    10141 agtaatgagt catgaacgtt attcgggaga aataaagaaa tgatcgacaa ccgcaccgcc
    10201 agcgccattg accaggcatt acagaaacat gatacacccg tcggcccgtt attttttgta
    10261 acacgccacg gaagaacaaa aaaatgcctc acccgaaaaa cggcaattcg ttacctggca
    10321 ttctttatga ccacccgcgc ttttgaacgt tcaggattcc gacagcgcca tcctgacaag
    10381 cgttttatct tcaacgggaa tgagatatgg aaacgaggag aatcaaccac agagtatacc
    10441 cgcgcacacc agcgaacaat cagacgactg cgcagactca tcgctaggaa acagtataca
    10501 gaaaaatggt tcagaaaata tgacacatgg agcgccggat attacgaact gatggcaaca
    10561 aaaccattct gacgtaaacg aaattaacca tgacgcaatt aaataaggca agccgaatac
    10621 atcaggagga ccatgaacat ttatttcaaa atagttatat cactggcaat tatctcatgt
    10681 atttacggat taatcgttcc ggccctcata tcaatgaagg atacggtagc agtgatttct
    10741 ggctttgctc tggcgtgtct gaccccgccg tgcatttgtg ccatttataa ggggctttct
    10801 ttcaccaagg ataaaagatg aaaaaaatta ttttttcttt agccattgtt ctgcctgcca
    10861 ttggccttgt cggttgtgat cgtgttgagc ctggtaatgt gggcatcaaa gtcaacaaac
    10921 ttgacgacga caaaggcgtc ggtgaagtgg tcggggttgg tcgctactgg acaggctgat
    10981 gcgattcgca caaaagccca ggctgaagcc gatgctattc gtttacgcgg tgaagctctg
    11041 cgtcagaacc ccggtgttgt ggagctggaa gccatcaata aatggaacgg cacgctgccg
    11101 caatacatga ccagtggtgc caatacacca tttatccagg ttaaataact taatatgccc
    11161 ggcagaccgt cgggctaagg gaaaagcaga tgaacactca taatactcaa ccgcaaataa
    11221 tgaactatga cccaaatctg acgtcatgcg gacgcatggc aaaacaaacc gttcgattaa
    11281 ctttcgggct atgggaatac cgcgaaacat tcgaagtcac tgtcggtggc aacctgaccg
    11341 gactcgatgt tatcagttgc gctattgaaa gcctgtacgc aacgctgcct tatgaagaag
    11401 tcgaggatga gcgtacaggg gaaacagaca tcatggccac cattaatatt ggcgaactga
    11461 tatgccagga tgaagacctg tccggagagc tctggcttgc cgggatgctt atctcagcag
    11521 aaattatcag tattgaaccc gctacaaaca tacggctctg aagttctcgc tattcagaga
    11581 gcaggagaaa aaatgttctc tttgattaat cagggacaac tgtataccga caatgccgat
    11641 tacccggtaa aaattgttcg ctgcataaac aacactgtgt tgtacagaag aatggatggg
    11701 cgaacacagt cagtaaaaat aaacgatttc aatgaactgt ttgaacggat tgatcaccag
    11761 gaataccgac aaattctggc agaaacagag caggaagctc atctgaaaaa attacgggcc
    11821 atgaaaagga agtaaagaat gaataaagcg tttgagctat gggtgcgcca gcgttacggc
    11881 aatcgctatg acctgacgcg agatgttgac ggtttctact gtcgtgaaat tgtgaaacga
    11941 atgtttgaag tgtggtgcca ctgccgtggg ctgagtgttg tgtgaggtaa tgtatgagca
    12001 atgtgattca actggctccc aatgaatggg tttgtgaaag cgttcttatc gcaattaccg
    12061 ggctcaaacc aggcacaatt ctccgagccc ggaaagaatg ctggatggta ggaagagagt
    12121 atattcacgt atcaccagat ggtaatccaa agccatccag cgaatgtatg tataacagaa
    12181 aagcaataga tgcctgggtc gcttcaatga aaaacaaaca acctgggtga tttaatgcca
    12241 tgaagtatgt aagctcgttt cgctcttggg cgtctggagg tatcaatgga taaagtcaaa
    12301 tatccaacag gcgtcgaaaa ccacggtggc acattgcgca tctggtttaa ttttaaaggt
    12361 aaacgtgtca gggaaaatct tggtgtccct gacactgcca agaacaggaa gatcgctgga
    12421 gaactgcgga catcggtatg ttttgccatc cgcacaggaa actttgatta tgctgcacag
    12481 ttccctgact cccctaacct tcaggctttt ggggtaagta aaaaagaaat tacggtgaaa
    12541 gaacttgaag aaaagtggct ggatctgaaa cgaatggaaa tctctgcaaa tgcattcaat
    12601 cgttatgaat ccgttgcaag aacgatggtt ccgaaaattg gaggtagcag actggtgtca
    12661 acggtgacca aagaggaatt gctgtatatc aggaaagatt tgctgaccgg acaccaaaat
    12721 ccaacaaaag gtaaggctcc ggtaaaagga cgaagcgttg tcacagtaaa ttattacatg
    12781 acgacaatcg ctggaatgtt tcagtttgct gcagatcacg gttacttaga agcaaatccc
    12841 ttcgagggaa ttaagcctct taaaaaagcc agggcagagc cagatccgct aactcgtgac
    12901 gaatttattc gcctgataga tgcttgccga catcagcaga caaaaaacct gtggtcattg
    12961 gctgtgtaca caggaatgcg tcatggtgaa ctggtctccc tggcctggga agatatcgat
    13021 ctgaaagcag gaacaattac tatccggcgc aattatacga aactcgatga gttcactcta
    13081 cctaaaactg aagcaagtac taacagggtt atacatctta tccagcccgc tatcagtgtc
    13141 ctgaaaaatc aggctgaaat gacaagactg ggtaagcagc accacatcaa ggttcaacta
    13201 cgtgaatatg gacgttcagt gaatcatgaa tgtactttcg tatttaaccc ccaggtggtt
    13261 agaaaaagca aacaggtagg ttttatctac aaggtagatt ccattggcga ctcatgggaa
    13321 tcagctatta agcgtgcagg catcaggcat cgaaaggcat accagtcacg acacacttat
    13381 gcgtgctggt cattatctgc cggagcaaat ccaagcttca ttgccagcca gatgggtcat
    13441 gcaagtgccc agatggtgtt caatgtatac ggagcatgga tgactgacag caatgcagaa
    13501 cagatcgcaa tgctgaatca gaagctggca gattatgtcc caatgatgtc ccatggtcac
    13561 caaagtgaca caagagactt attaaaatca gtgggttagc cttcaatacc cgtcatgtta
    13621 actgcgtgga gggcaacacc acgctttacg ccctgccgaa acccgaggtt gtcctgcgct
    13681 ggcgtgaaca gaccacagat gacttccgct tctgttttaa gtttccggcg accatttcgc
    13741 atcaggcagc attacgacat tgcgatgatt tagtgactga atttttgacc cgcatgtcac
    13801 cgttggctcc gcgcattggg caatactggc tgcaactgcc tgccacattc ggcccacggg
    13861 agctgcctgc gctttggcat tttctcgatt ctctccctgg cgaatttaat tatggtgtgg
    13921 aagtccgcca tccacagttt ttcgccaaag gggaagagga acaaactctt aatcgcggtt
    13981 tacatcagcg cggcgttaat cgggtgattt tagacggccg cccggttcat gcagcatgtc
    14041 cacacagtga agctattcgc gacgctcaac gaaaaaaacc taaagttccg gtacatgctg
    14101 tactgacggc gacaaatccg ctgatccgtt ttatcggtag tgatgatatg acgcaaaacc
    14161 gggaattatt tcaggtctgg ttacagaaat tagcgcagtg gcatcagacc actacgcctt
    14221 atcttttttt acatacgcca gacattgccc aggccccgga actggtacat accctgtggg
    14281 aagacttacg taaaacgctt ccagagatcg gagcagttcc ggctattcca cagcaatctt
    14341 ctcttttctg aatttgccac ctatcataga caggtgccat cggccatttt aaagggagtt
    14401 tgtatggtaa gcgcgctata tgccgtttta agtgcgttgt tattaatgaa gttctctttt
    14461 gatgtcgttc gcttgcgttt gcagtaccgc gttgcctatg gtgacggtgg ttttagcgaa
    14521 ctgcaaagcg ctattcgcat tcatggtaac gcggtggaat atattcccat cgcgattgtg
    14581 ctgatgctgt ttatggaaat gaatggcgca gaaacctgga tggtgcatat ttgcggcatc
    14641 gttttgcttg ctggtcgtct gatgcattat tacggttttc atcaccgtct gtttcgctgg
    14701 cgacgttccg gcatgagcgc cacctggtgt gcgctgttgc tgatggtgct ggcgaatctt
    14761 tggtatatgc cctgggagtt ggttttctcc ctgcgttagc gcacaatacg ccactttctt
    14821 tttcccggat ttttacgtta tgtctcaccg cgacacgcta ttttctgccc ctatcgccag
    14881 actgggcgac tggacctttg atgaacgggt agctgaagtc ttcccggata tgatccagcg
    14941 ttccgttccc ggctattcca atattatttc catgattggt atgttagccg agcgcttcgt
    15001 tcaacctggt acgcaggttt acgatctggg ttgttctctg ggcgcggcga cgctctcggt
    15061 gcgtcgcaac attcatcatg ataattgcaa aattattgcc atcgacaact ccccggcgat
    15121 gattgaacgc tgccgtcgtc atattgacgc ctataaagcc cctacgccag tagacgtcat
    15181 tgaaggtgat attcgcgata tcgccattga aaacgcatcg atggtggtgc tgaattttac
    15241 cctgcaattc ctggaacctt ccgagcgcca ggcattactg gataaaattt atcaaggact
    15301 gaacccaggc ggcgcgctgg tgctttcgga aaaattcagt ttcgaagatg ccaaagttgg
    15361 tgaactgttg ttcaacatgc accacgactt taaacgtgcc aacggttaca gcgaactgga
    15421 gatcagccag aagcgcagca tgctggaaaa cgtgatgctg accgattccg tggaaaccca
    15481 taaagcacgc ctgcataaag ccggttttga gcatagcgag ctgtggttcc agtgctttaa
    15541 ctttggttca ctggtggcat taaaagcaga ggacgctgca tgatcgactt tggtaacttt
    15601 tattctctga ttgccaaaaa tcatctttca cactggctcg aaacgctgcc cgcgcagatt
    15661 gctaactggc agcgcgagca gcagcacggg ctgtttaagc agtggtccaa cgcggtggaa
    15721 tttctgcctg aaattaaacc gtatcgtctg gatttattgc atagcgtaac cgccgaaagc
    15781 gaagagccac tgagcaccgg gcaaattaaa cgcattgaaa cgcttatgcg gaacctgatg
    15841 ccatggcgca aagggccgtt ctcactgtat ggcgtcaaca tcgataccga atggcgttcc
    15901 gactggaaat gggatcgtgt tctgccccat ctttctgatt taaccggacg caccattctg
    15961 gatgtcggct gcggcagcgg ttatcacatg tggcgcatga ttggcgcagg cgcgcacctc
    16021 gcggtgggga tcgaccctac gcaactgttt ctgtgccagt ttgaagcggt gcgtaaacta
    16081 ctgggtaacg atcagcgcgc acatttgtta ccgttaggta ttgaacagct tccggcactg
    16141 aaagcctttg ataccgtctt ttcgatgggc gtgctttacc atcgccgttc gccgctggag
    16201 catctctggc agttgaaaga tcaactggtg aatgagggtg aactggtgct ggaaacgctg
    16261 gttattgatg gcgatgagaa cacggtgctg gtaccaggcg atcgttacgc gcaaatgcgt
    16321 aatgtctatt tcatcccttc cgcgctggcg ctgaaaaact ggctgaagaa gtgtggtttt
    16381 gtagatatcc gcgttgtgga tgtgtgcgtt accactactg aagagcagcg acgcactgaa
    16441 tggatggtta ccgaatctct gtccgatttc ctcgacccac atgatccgag taagacagtt
    16501 gaaggttatc ctgcgcctaa acgcgcggtg ctgattgcgc gcaagccgta aaggtctggc
    16561 attactgccg gatgcggctt gaatgcctta tccggcctac aaacccttgc taattcaatc
    16621 tattgcaggg actatgtagg cctgataagc atagcgcatc aggcagtttt acgtttgcat
    16681 aacctcagcg cccgtttccg ggcgctattc acttcttatg cctgaatagc tggctgatca
    16741 aacgccgtta acttcggcgc attgcccgta tatttttcga tatacaccag cgcagagtta
    16801 ccggcacagg catttgccag ctgcgagctg gggatatccg ccgttaacac gttcgcactg
    16861 ccgtttttac acaagccatt ttccagatct ggccatgcac cttcatgcac gcataccacg
    16921 ccttttttga tcccgtcagt caccaccgcg cctgtcagaa tctgaccacg tttgttccac
    16981 acacgcacca gatcaccatt cgcaatacca aagcgagcag catcttcggt gtgaatagtg
    17041 attggttcac gatctgcaac cgcatatttt ttacgcagtt ccgcatagtt aagctgacta
    17101 tgtaaacggt gtgccggatg tgcggtcaga agctgcaact gcttctcgtc ggcggtaccc
    17161 ttccactcat caggcgcaag ccaggttggg tgtgccgggc aatccttata gccaaatttt
    17221 tccagcgttt tggagtaaat ctcaattttg ccgcttggcg tacccagcgc atttttcacc
    17281 ggatcggcgc ggaaatcagc ataacgaacg tactgttcgt tcttctcgct gcggcgcatt
    17341 tcgatcagtt tattttgctg ccagaaggca ttaaacatcg gcatagtcac gcgttgcgca
    17401 cgagcacctt tctgagcggc atcatagaaa aatttcagcc acgccatttc atctttacct
    17461 tcggtataga tctcttttcc gccaggtttc agtaattcag caagatcggc aaatacgtca
    17521 aaatcgttac gcgcttcaaa ttgcggagca acagcctgct tcatcggcac aatatgctgg
    17581 ttgctgtaat caccggtcat cgtcaagtca ttgcgctcaa acgatgtggt gatcggtaat
    17641 acgatatctg catgtttagc agctgcggtc cagtagcatt cagaaacgac gatcatctcc
    17701 ggtttctgcc atgctttgat cagacgatta gtatcctggt gatgggtaaa gttaccgcca
    17761 cccgcccacc agatcatttt gatattcgga tacgtttgtt ctttaccgtt atgctgatat
    17821 ttgccaccag gattttccag cgcatcgacg atacgggcaa caggaatcgc cgtcattccg
    17881 ccatcatcag cggcctcgct ggcctgtccg gcaatcgccg cagacatttc cggcagcacg
    17941 ccgccaacac gcgtcggatt gccaccgttg gagtaatgat aagagaaacc aaaaccgccg
    18001 cccggtgtac caatctgccc taacatcgcc gccagcgtca ccagcatcca gtgtttctgt
    18061 tcaccatatt gctggcgctg aattccccag ccagccatca gcattgtgcg attcgccgcc
    18121 atcagttcag cgagtttgac tatctgcgct tccggtacgc cagtaatttc cgccgcccag
    18181 gccgcgctct tcggagtatt atcgctctta cctgtcagat actcttcaaa ctgcggatac
    18241 ccggtggtgt atttttcaag gaacacttta tcgtgtttac cttgtgtcat cagggtatgc
    18301 gcaatcccta acatcagtgc cacgtcggtg cccatattcg gcgcgatcca ggtagcatta
    18361 tcaccaaaga actcgatggt ttcggagcgg ataggatcaa tggcaatcac tggtttgcca
    18421 gattttttca gctgatggaa gtattccagc ccttgctcat cggtactgct ccaggcaatt
    18481 tttaaggtat tcagcgggtt catcccccac agcaccacag cctggctgtt ttccagaatc
    18541 agcggccagg aggtctgctg ttcatacacc tctacagaac cgaccacatg cggcatgatc
    18601 acctgtgcag ccccggttga ataatcgccg ctatgcccgg aataaccgcc cgccaggttc
    18661 atataacgtt gcagtaaggt ttgcgcttta tgcaacacgc cagaagagcg ccagccgtat
    18721 gatccggcaa aaatagcaga tggtccgtta gctttgcgaa tgcgatcgtg ttgctcatga
    18781 atcagtttta atgcttgctc ccagctcacc tgtacataag tatcttcgcc acgacctttc
    18841 gccggttgca gtggattatc gagatagctt tttcttacca tcggatgctg aatacgtgcc
    18901 gtggtgtgta cctgatccgc cgccgtagac tgtaaggagt tcggtatggt tttcgccagc
    18961 gcgcctgttg aagaaacaat cttgccgtcc ttcacttcta cgttcatcgc tccccaacgt
    19021 cccgcggtga ggattttacc gcccttctct tctgcccatg cggggagcgg tgctgccgat
    19081 gtcaccacca gcgctccagc ggcaataccg ctgtgtttaa taaattcacg tcttgttaat
    19141 gtcataactt cctccctgat caacgaggat cactgtttct cggtaatatc tttggcgttg
    19201 tactggaaat accgcgttaa aatgtccagt tcgttttcgc tcatgctggt tcgcgcaccc
    19261 attcctttgg caatggacgg ccatgcattg acggtgtaat ggtcagcggc aataggcgca
    19321 tggcaaccag cgcaataggt atcgtcaagt ttttcagcgt attgccatag cggtttacgg
    19381 tccgctaatg cgggatcggt aagcgcaccc tgtaaagacg cctgacgcca ttgattgccg
    19441 tattcgtcag cctgccattc cccgtttacc gtgagcgcct tgataccttc ttcacttaat
    19501 gtggctagcg ccagccgttg acctgccgcc aggtagagcg tgttttcact gccctgcatt
    19561 tgataaccct gcaacagaac gatcggctgt ttgccactgg catcaacgac ggtgagatcg
    19621 gtaccaggat tcacggtagc cagctcgcct atgcgagaag ttttgaaagg ataaatatgt
    19681 gcgccattag tcactgaagt agcggcctga ctttccagct catgcgccgc gttgtcatcc
    19741 atttttattt ctggcggaaa atgggcaatg cctttatgac aatcgataca ggtttcgccg
    19801 cccttttgtg ctttgttatg cattttctgc gcagattcac tttgcgaggc aatatccatg
    19861 gcatcaaaag aatggcaact acggcacgtt gcagagtcag ttgcttttaa ttctttccat
    19921 actgtttcgg ccatttcctg gcgatgagtt tcgaacttat cgtcactgtc tattttgccg
    19981 ctaacaaatt catgataaat atctttagat gcttttaatt tagcaaataa ataatccatc
    20041 cctgactttg gaatatggca atctgcacat tccgcacgta tccctttctg gttcgaaaag
    20101 tggacagttc cctgatattc ctcaaaaggt ttactcatcg agtggcagga aaggcaaaat
    20161 gctgtatccg acgttttatg taaggctttt tgcgccagca ataacccgcc gccaccaacc
    20221 acaaccgcta tcagcaaaaa caataaccca atgcgttttt tccctcgcat agattcctct
    20281 aaataaattc cagaacaccg aaatcattgt ataattaaat acacaacgaa ttaaccgctt
    20341 gcataactcg gcacaacact gcctgaaata atcgataaag aatatgattt attacaatgt
    20401 aatcattaat tgctaaggaa taacccagtt gctatttaga atatatattt atcagtttta
    20461 gcaatttaaa tcccataatc aatgtgaata taaaaaatat tattagcaca acgctatgtt
    20521 cactgtcacc cgctcaacag atcacggtta tcgttcgttt tttatactgc tcagggataa
    20581 aaaaaggccc ctgttgaaat tgcaggggcc tggtacgagc aagcatcata ttgggcgaca
    20641 tgatgcaacg gtaaaaatca tttggcctga tggcgttcaa tgattccttt catttcagca
    20701 accgccgccc cgtctacgat ataacgcgaa tactcgtccg cgtgttcatc tgatgacatg
    20761 gacaatcctt gattacgata acgcatcggt gaggcttgcc acgctcccgc ggagctatgg
    20821 acttccagca ctccggcatc gaggaagtgg tgcaggtttt ctgcacggac tcctgctccg
    20881 gccataatga ttggagcatc acgatgggca ataagttcca taatttttga taaaccttgc
    20941 agtgcgtctg atttttgccc tgatgtcagt acccgggcaa tgcccaattc cgcaagatta
    21001 ttgagtgtat ataaagggtt agcgcacata tcgaaggcgc gatgaaaagt cactgccagc
    21061 ggaccggcag cagccattat tttttccatt cgtggcatat cgacattccc gtcaacatcg
    21121 agaacgcccg tcaccagtcc aggaaaacct aattcgcgga ccgtgcgcac atcctcaaga
    21181 atggcggcaa actcaccgtc gctgtagcaa aaatcaccac cgcgtgggcg aattatcgga
    21241 tgcacaggga tcgtcacccg ctggcgcacg gatttcagta cccccaacga cggcgttaag
    21301 cccccctctt ttggggctgc gcataattca actctgtctg cgccgttttg ctgcgccgtt
    21361 agtgcacatt ccatgctgta acagcaaatt tccagtaatg ccatttttgc tccttaatta
    21421 cgctgactgc tcgctggcaa cgatctcttc aatggaccac ggatgaaact taatagttgt
    21481 tttgccatcg gtgaccgcca gcgtcggatt cggtaatcgc tcatgctcac cttttggtga
    21541 actggtttta actgagatcc ccggtaggct gagtccttca tcagaaagca atgccagcgc
    21601 acgggcattc agcgtttctg gatcacccgg cagaacgatt tcaatatgtt cccaaccttc
    21661 gtgtgggtaa cgtttttccc cgggccacgg tagctccaca atagaaaact gccagtgcgc
    21721 aacctgtacc ggttcatgca atttaaacag acaaatcggt ctgccattga tcatattttc
    21781 tgacaaaagc tcgccacact gttcaaaccc gcgacgccag cgttcagcag tggcgttttg
    21841 atggcaacgc aaagaaatgt gatcggcagt cagcggagtg atattcaacc ccagacggag
    21901 ggaaagttca tctaatgcgt gggtaaatcg cggtaaatcc gatgcaatat cctgcagctc
    21961 gtcgatagat tgccagttcg ccataatcac tcttcgtctt tcagtaaaag cgttaattta
    22021 ccctgttgcc ctgcgccaac caaccgctga tttcacgccg cttctgatgc aatagtgaaa
    22081 acggcaatac gccacgcgca cgttgctgac gaaaacagcc atttgcagta tactcccgcc
    22141 ctaatttctt taactggtgc gggcaatttt tgctcgcttc atcaatgtaa ggtattccgg
    22201 tgaatattca ggctcttctc tcagaaaaag tccgtcaggc catgattgcg gcaggcgcgc
    22261 ctgcggattg cgaaccgcag gttcgtcagt cagcaaaagt tcagttcggc gactatcagg
    22321 ctaacggcat gatggcagtt gctaaaaaac tgggtatggc accgcgacaa ttagcagagc
    22381 aggtgctgac tcatctggat cttaacggta tcgccagcaa agttgagatc gccggtccag
    22441 gctttatcaa cattttcctt gatccggcat tcctggctga acatgttcag caggcgctgg
    22501 cgtccgatcg tctcggtgtt tctacgccag aaaaacagac cattgtggtt gactactctg
    22561 cgccaaacgt ggcgaaagag atgcatgtcg gtcacctgcg ctctaccatt attggtgacg
    22621 cagcagtgcg tactctggag ttcctcggtc acaaagtgat tcgcgcaaac cacgtcggcg
    22681 actggggcac tcagttcggt atgctgattg catggctgga aaagcagcag caggaaaacg
    22741 ccggtgaaat ggagctggct gaccttgaag gtttctaccg cgatgcgaaa aagcattacg
    22801 acgaagatga agagttcgcc gagcgtgcac gtaactacgt ggtaaaactg caaagcggtg
    22861 acgaatattt ccgcgagatg tggcgcaaac tggtcgacat caccatgacg cagaaccaga
    22921 tcacttacga tcgtctcaac gtgacgctga cccgtgatga cgtgatgggc gaaagcctct
    22981 acaacccaat gctgccagga attgtggcgg atctcaaagc caaaggtctg gcagtagaaa
    23041 gcgaaggggc gaccgtcgta ttccttgatg agtttaaaaa caaggaaggc gaaccgatgg
    23101 gcgtgatcat tcagaagaaa gatggcggct atctctacac caccactgat atcgcctgtg
    23161 cgaaatatcg ttatgaatca ctgcatgccg atcgcgtgct gtattacatc gactcccgtc
    23221 agcatcaaca cctaatgcag gcatgggcga tcgtccgtaa agcaggctat gtaccggaat
    23281 ccgtaccgct ggaacaccac atgttcggca tgatgctggg taaagacggc aaaccgttca
    23341 aaacccgcgc gggtggtaca gtgaaactgg ccgatctgct ggatgaagcc ctggaacgtg
    23401 cacgccgtct ggtggcagaa aagaacccgg atatgccagc tgacgagctg gaaaaactgg
    23461 ctaacgcggt tggtattggt gcggtgaaat atgcggatct ctccaaaaac cgcaccacgg
    23521 actacatctt cgactgggac aacatgctgg cgtttgaggg taataccgcg ccatacatgc
    23581 agtatgctta cacgcgtgta ttgtccgtgt tccgtaaggc agaaattaac gaagagcaac
    23641 tggctgcagc tccggtaatc atccgtgaag atcgtgaagc gcaactggca gctcgcctgc
    23701 tgcagtttga agaaaccctc accgtggttg cccgtgaagg cacgccgcat gtgatgtgtg
    23761 cttacctgta cgatctggct ggtctgttct ctggcttcta cgagcactgc ccgatcctca
    23821 gcgcagaaaa cgaagaagtg cgtaacagcc gtctgaaact ggcacaactg acagcgaaga
    23881 cgctaaagct gggtctggat acgctgggta ttgagacagt agagcgtatg taatcgattt
    23941 ttcgtgagag taaagcctga tcagggttac ctgatcaggc ttttttattg ccatctaaat
    24001 gtattctgaa aatggacatg ccattgtttt ctgactgttg gataagaggc cagaagcgta
    24061 atatccggcc ccagggaaac gataacggtt gaatttaagg aataccgcag tgtttaaatt
    24121 tcttgtatta acattaggca ttatctcttg ccaggcttac gcagaagata cggttatagt
    24181 aaacgaccat gacatttcag ccatcaaaga ttgttggcaa aaaaattcag atgatgatac
    24241 tgacattaac gtgatcaaat catgcctgcg acaagaatac aatctcgtcg atgcgcaatt
    24301 aaataaagcc tatggtgaag cttatcgtta tatagaacaa gtgccacgca caggtgtaaa
    24361 aaaacctgat accgaacaac ttaacttgct taaaaaatca cagcgagcct ggctggattt
    24421 tagggacaaa gaatgtgaat taatcctttc aaatgaggac gttcaggatt taagtgaccc
    24481 ttattctgaa tcagaatggc tctcatgtat gatcatacag accaatacgc gaactcgcca
    24541 gttgcagcta taccgtaact ctgaagattt ttatccaagc cctttgacaa gaggataatt
    24601 cacatctttt tggcatgttt tgttgcaagc tattcctgat aaataattgc aacaagacat
    24661 cgagcctttt tcactgagtt attaaacata ctcgcgagcg cgtaattttt ttgtccttca
    24721 gcgataattc acaatcactt cattacgttg tacctttagc ggtggaatta accgcccacc
    24781 gcctggcact tcccagataa atcgcaacgg ttctgctgcc gctataccgg aaaaggccac
    24841 ggtggttccg ctctgcccct ctaattcgac acaacgagat tgcgaacaca agcgaacccg
    24901 cagtcctgaa ggtgtcgggc cgataagctg ataacgccac gctaccagcg tcatcaatcc
    24961 tgaagcaggt tgtcgcgtag aaagaggcgc agacgacatc gactcaccgc gatgatttag
    25021 cgtaattcct acactacttg cctgccacat cccctccccg gcggcttgca ccagcagcgg
    25081 aaacaataat attgctaata aggttctcat tatttgccgc caattgtcgc cgtcatgcgg
    25141 atatgtcggt tatcagacag ttccagattc gacaggacca ctaactgcgg caagctgcgg
    25201 cgcaggaagc gagacaataa tggtcgcagc gcgtggttca ccaacaatac tggcggcgca
    25261 cccagcatct cctgacggga tagcgcttcc tgagtttgcg ccagtaaacg atccgccagc
    25321 cctggctcca gtcctccccc gccctgcagc gcctgtagta acaaactttc cagcggtgta
    25381 tcgaggccaa taacatggac ttcatctttg ccaggaaacc actgctgggt aatcgcccgt
    25441 cccaacgcca cgcgcacgac ggcggttaat tcatgtggat cgctttggat gggcgcatgt
    25501 tccgccagcg tttcgagaat ggtgcgcata tcgcgaatcg gtactttttc atcgaggaga
    25561 ttttgcagca ctttatgcag tgtggtgagc gtgacgacgc caggaacgag atcttccgtc
    25621 agctttggca tctcctgggc gacgcgatcc aacagctgtt gcgcctcctg acgaccaaac
    25681 agctctgcgg catgctggct aatgaggtgg ttaagatgcg ttgctaccac cgtgctggcc
    25741 tcaaccactg tgtacccctg aatctgcgcc tgttctttta gcgcactttc aatccagata
    25801 gcattcaggc caaatgccgg atcgacggtc gcctcaccag gtaacgtccc ggcagcggtt
    25861 ccagggttaa tcgccagcca gcgccccgga taagcatcac cactgccaat ctccacgcct
    25921 ttcatcaaaa tgcgatagcg ggcaggttgc agatccatat tgtcgcgaat gtgcaccact
    25981 ggcggcagaa atcccatctc ctgggcaaat ttcttgcgga tactgcgtat acggcccaac
    26041 aactcaccat cctgctggaa atcgaccatc gggatcagtc gataacccac ttccattccc
    26101 agagaatctt ccagttgtac atcgttccac gtcgcttcga caacggtatt attctctgcc
    26161 atttttaccg gtttgggttc gacaggcgct ttttgttcgc gtccgcgtat ccaccaggcc
    26221 agccccagca atccggcagt gaacagcaaa aataccaggt tcggcattcc aggcaccagg
    26281 ccgagtaaac cgagcacggc ggcgcttaac aacataacgc ttgggttact gaaaagctga
    26341 ttcaccatct gctcgccaac atcctgatcg gtgctgacac gcgtaacgat gacccccgcg
    26401 gcggtagaaa tcaccagcgc cggaatttgt gccaccagac cgtcgccaat ggtcaatagt
    26461 gtataacttt ccgccgcgtg tcccatgctc atgccatgtt gcagcacgcc gaccagcaac
    26521 ccgccgacaa cgttaatgac catgatgagg atcccggcga tggcatcgcc gcgaacaaac
    26581 ttacttgccc cgtccattga gccgtaaaaa tcggcttcct gagtcacttc ggagcggcgt
    26641 tttttcgcct catcttcacc aatcaatcca gcgttaaggt cggcgtcaat cgccatctgc
    26701 ttacccggca taccatcgag aacaaagcgc gcacccactt ctgcgatacg cccggcacct
    26761 ttggtaatga ccataaagtt gatgatcacg agaatgacaa acactacgat accgatagcg
    26821 aaattgccac caacgaggaa gtgaccgaat gcttcgacca ccttcccagc cgccgccgcg
    26881 ccggtatgcc cttccatcaa aatgatacgg gttgaagcca cgttaagtgc cagacgcaac
    26941 aacgtagtaa acaacagaat ggtcggaaac gcagcaaact caagcgtgcg ctgggtaaac
    27001 atcgccacca gcaacaccat gatcgacaag gcaatattga aggtaaacaa caggtcgagt
    27061 atgaatgcgg gcagtggcag caccatcatc gacaagatca acaggatcaa aatcggtccg
    27121 gcaaggatct gccattgtgt cgatttcagg tttgcgggca ggcgcagcat cgcggccaga
    27181 ttactcatgg gtcggtttct cgttaataaa atccagggct tccggcaccg gaagatgagt
    27241 aggttgtaca gggcgctgtc caccagccag acgccagcgt ttcagttgcc agacccaggc
    27301 cagcacttcc gccaccgcgg cgtacagttg acccgggatt tgttgaccaa tctccgcatg
    27361 tcgatacagc gctcgcgcca gcggcggcgc ttcaagcgtc gggacgttat tttcagcgcc
    27421 aatttcacga atgcgcagcg cgaccagccc tgcaccttta gcgaccactt tcggtgcgct
    27481 cattttgttt tcgtcatact gcaacgctac cgaatagtgg gtcgggttat tgacaatgac
    27541 atccgctttc ggcacatcgg ccatcatccg acgccgtgca gcagctcgct gcatctgacg
    27601 gatccgccct ttaacatgag ggtcaccttc gctttgtttg aactcatcac gaatatcctg
    27661 ccgtgacata cgcagctttt tcaggtggct gaatatttgg aaaaagacgt caaatcccac
    27721 cattggaatg acaccaagca ccaccagcag tgcgcatagc cctaccaaat ccatcgcatt
    27781 acccatggcg gtaatcggag actcggccat caagcgcatc atctgcggcc agtgatgcca
    27841 gagaaaaaac cccgtcacgc tgccaaccag gatggttttc aaaattgctt taagcaactc
    27901 cgcgccagtc tgagccgaga acatccgttt aatgcccggt agcgggttga gtttggaaaa
    27961 cttcggctgc aaggatttgc cgctaaatac cagccctccc agcatgaccg gagaaatgag
    28021 cgccaccagc accacgccgc taatcagcgg cagcagcgcc agcatggctt ctctgatcag
    28081 cagaataatc tgcccgagga tcagattcgg gtcattgata atactgtgat caaaatgcag
    28141 cccagcggag agcatgcccg acaatcgacg ggccagcgac acaccgccaa accagataac
    28201 actaacgccc accagcaaaa tcagcagtga ggtcagttca cgggaacgcg ggatttgccc
    28261 ctcttcccgc gctttttcta gtcggtgagg tgtgggggct tctgttttgt cgtcgctctc
    28321 gtcagacacg tcgccaatcc tggaaagagt attaagcgtg aatgatgcca gagcgcaaag
    28381 cgttcaatgg tttgagtaag gggcaaaaca ggcgggattt agggcttttg ctgccacaca
    28441 tcaagcatag tgtgcgtttg tcggatgcgg cgtcatcgcc ttatcagacc gcctgatatg
    28501 acgtggtcac gccacatcag gcaatacaaa tcaaaatcca agactatcca acaaatcgtc
    28561 cacctgatcc tgactggcta ccacgccggc tttgctggta tcgacctgag gtccattaag
    28621 caaactctgg ttttcacgtt ttggacgcga ctcctgttcc gggatgtttt ccaacagcac
    28681 catcagcaac tggcgttcga tctcctgaat gacatccatc atccgcttaa tgacctgccc
    28741 ggtgagatcc tgaaaatcct gcgccatcat gatttccagc agttgcgcgt tagtaaagct
    28801 ggtatgcgcg ggtacatctg ccagaaattg tcgtgtatct gttaccagtt cacgggcgtc
    28861 ggcaaggtca atcggatcgg caaaccagtc atcccaacgt tgggttaacg cttttgctga
    28921 tttctccatt tgatcctgat gcggttgtga cgcctcaaca ctgttcagcg cccgctccgc
    28981 agcctgggcg gtcatctgca caacatagta caaacgatcg cgcgcatcgg ggatggcttc
    29041 cgccgcttcg gcaatggcct gatccagccc cagttcccgc aaactgtcgc gcagcatacg
    29101 cgtcaggctg ccgatgcgcg caatgatatc gccagctgaa tgctcgtcag caggtttgat
    29161 tgatggttgc atcatagtcg catcctcaca tgcccagttt ctcaaagatt ttgttgagtt
    29221 tttcctccag cgtcgcggcg gtaaatggct tcaccacata gccactggcc cccgcttgcg
    29281 ccgcagcaat gatgttctct ttcttcgctt ctgcagtcac cattaacact ggcaatgccg
    29341 acatcgcgcc atccgcacga attgttttca gcaattccag gccatccata ttgggcatgt
    29401 tccagtcgga gataacaaat ccataaccgc ctgcctgcaa cttattgaga gcgtcgacgc
    29461 catcttccgc ttcctcaaca ttattgaatc ccagctcttt aagcaggtta cgcactatgc
    29521 gtcgcatggt ggaaaagtca tccacaacca aaaatttaag ttctttatcc gccatttcac
    29581 actcctgatt taaatacgta tcgcctgtcc ggcactaatt tttgccaaca tttgctggct
    29641 tacctggcta agatcgacca cttcgcagac accacccata ttgatggcct cgcgcggcat
    29701 gccgaacacc acgcaacttg cttcgttttg cgcaagggtc catgcccccg cctgacgcat
    29761 cgccaacatt cccgccgcgc cgtcgttgcc cataccggtc aggatcaccc caaccgcatt
    29821 acgccccgcc tgtttggcga cagaatggaa caacacatct accgaaggcc gatgacggtt
    29881 aaccgccggg ccatcgtgaa ttttgatttg gtaatttgcg ccactacgcg acagctccat
    29941 atgccgatcg cccggcgcaa tataggcatg ccccggcaag acacgttctc cgtcttcggc
    30001 ttctttaacc ccgatctggc aaagcttatt aagtctgtcg gcaaaagagc gggtgaaacc
    30061 gggcggcata tgttgggtaa ttaacaatgc cgggctggaa agcggcaacg gttgcagtac
    30121 gtgacgaatt gcctcagttc cacccgttga agcaccaatc gcaatcagtt tttcagaact
    30181 caacaacgga cccgccttca gcgttgtcgg tgctgacaat ggcttatgtg ctgcaaggct
    30241 cgcctttgct gccgtacgca ccttttcagc aatcatttcg ctatacgcca gcattccttc
    30301 gcgaataccc agttgcggtt tggtgacaaa atctattgcc cccagctcca gcgcgcgcag
    30361 cgtgacttct gatcctttgc cggtcaagga agaaaccatc acaacgggca ttggacgcaa
    30421 acgcattaat ttttcgagga aatccagtcc gtccatccgc ggcatttcaa catccagcgt
    30481 cagcacatcg ggattgaatt tcttaatcaa gtcacgcgcg accagcggat caggcgcggt
    30541 cgccaccatt tccatgtcgc tatggctgtt gatgatttct gtcatgatct ggcgcatcag
    30601 tgccgaatca tcgacagata acaccctgat tttgctcatc gttaatcctt acttagcgca
    30661 tacaccgtct gaccacgcag cgtgaagcgg cgctcaaggt ggctaaagtt ttcagagtga
    30721 cccgcaaaca gcaatccgtc gggtttaagg agcggaacaa agcggcgcaa aatctcctgc
    30781 tgggtatttt gatcgaagta gatcatgacg ttacgacaga agatcgcatc aaacggcccc
    30841 ggcacggtgt actgtttctc cagtagattc agcggggcaa aatcaacata gttcgccaac
    30901 tcctgacgca cgcgtaccag cccttcatgc ggtcccgtcc ctcgcatgaa ataccgttgc
    30961 agttgctgcg gcgtcaggtt tttcaactct tcatggcgat aaataccgct tctggctttt
    31021 tccagcactt cggtgtcgat atcactggca aacactttcc agcgtccggg cgcggtgccc
    31081 aatgtgtcag ccagcgtcat cgcaatgctg tacggctctt cgccggtcga agccgccgcg
    31141 ctccatacgc gatactcgcc agaacggcga cgtgcgtgat ccgcgagcag agggaaatgg
    31201 tgtgcctcac ggaaaaatgc cgtcagattc gtggtcagcg aattgataaa cgcctgccac
    31261 tcaccgctgt gctgattaga ttccagcaag ttcagataat gaccgaaatc cgttagtccc
    31321 agcgaacgca aacgacgaac cagtcggttg taaaccatgt cgcgtttatg gtcagccaga
    31381 acgatcccgg ctcgttgata gatcaattga cttatccgcc gaaaatgcgc gtcggaaagc
    31441 gccaggcgct cggtcatctg taacaataaa gacgtttgcc cacagggcag agatgaagtc
    31501 atagcgcctt ctcaatcact tcaggatacc actggcgcaa tttgtaactg cgccgactca
    31561 tgtcgtgcta cttcatgttc ttcaagggta aataccgcca cacgcgacga aagatggtcg
    31621 gcctgattcg ccagttgttc cgttgccacc gccgcttctt ctaccagcga ggcgttctgc
    31681 tgagtcacct gatccatctg gctgacagcc tgtgcaacct gctcaatccc ccgctgttgt
    31741 tcttccgacg cagaggcaat ttctcccata atgtcgttca cgcgggtcac cgaactgaca
    31801 atatcgatca tggtcgcggc ggcgttattc accagtttcg aaccctgctg gacacgattg
    31861 actgactctt cgatcagccc tttgatctct tttgctgcct gcgcgctacg gctggcaaga
    31921 ttgcgcactt cacctgccac taccgcaaaa ccacgcccct gctctccggc gcgagccgct
    31981 tccactgccg cattcagggc cagaatattg gtctggaaag caattccgtc gataacgctg
    32041 ataatgtcgc caattttttg cgagctggtg gcgatctcct gcatggtgtg agtcatggta
    32101 ctgacctgaa caccgcccgc ctgcgccgtt gtcgcggcat tttttgccag ttccgacgcc
    32161 tgtcgtgcgt tatcggcgtt ttgccctacc gtggcggtta attgctccat actggcggcc
    32221 gtttgtgcca gcgatgccgc ctgctgttcg gtacgacttg agagatcgtt attgcctgcg
    32281 acaatctccg cgatcccaat gtgcatctca tggcttccct tacgcacatc actcaccgtc
    32341 ccacgcaaag cctgctgcat ggtcttcagg ctggcaaaaa tggcggtgat ctcattacga
    32401 ccatataccg caatcggacg cgccagatta cccgcagcaa tgctgtcaaa atggctacca
    32461 ataatggcca gtggttgaac aatcatcttg cgcgtccacc acagcgcact gctgatgtag
    32521 attgccgcaa caataatcat gctgataaac accagcgccg aaatctgata gttacgctga
    32581 ctttgcgcac tggcggcttc cagcacatgg ttgatctcca gctgccaggc ctcaaagtta
    32641 acgtcaaacg cattctgtga tccctgcacc ggcgcagtga ggaaatccga aagttgatta
    32701 ctttcaagcc aggtcgcctg atgttcgaga tcgttgtgcc agcgggcaaa acttttctcc
    32761 gtctcttttt gcaatgccct gacgtgctcg ttgcccgcag tcatcgccat aaaactttta
    32821 aacagcgtgg tggattgcgt cagactggcg cgcgccgtcg tcatcaacgt tttaatgtca
    32881 tccgccggat agctaagtgc cgtcagagtg cccgctttgt tcagcgcggt actggcctgt
    32941 aacattaccg cccgagtttg cgctaatgcc gcacgttgct gattgctctg ctcgacctga
    33001 ttcagtcgtt gcaaatcgtc gcgaaatgcc caaaaagaca tgccgttact gccaatctgc
    33061 aagatcccgc agagaatcaa aattaaaaac agcgtggtcg aaattcgaat acgattaaac
    33121 atcaacgctc cccatcaggc ggcaatgacc gcgttagtaa atactcgtca aaatgtttcc
    33181 cagtttggat cttgttcagc aattcgcagt cgtggctgtg tcggtggttg ctcactggca
    33241 ggacgggatg gtgtttgcgg tttattggtg agtgggctgg ctgccagacg gaacgtggaa
    33301 accgcttgcg ttaaacgact cgcctgttct tccagcgcag cggcggcggc agctgattcc
    33361 tgcaccagcg atgcgttctg ttgcgtgacg cgatccattt ccgaaaccgc caatgcgact
    33421 tgatcgatgc cacggctctg ttcatccgat gccgatgcaa tctcgcccat aatgtcagtc
    33481 acgcgagtga cagcattgac gatattgttc attgtttccc cggcgctttc gaccagcacc
    33541 gaaccggtat caacgcgtga gacggagtct tcaatgaggg ctttgatctc ttttgccgcc
    33601 tgggcgctac gactggcaag attacgcact tcacccgcca ccacggcaaa accacggccc
    33661 tgttcacccg cacgcgcggc ttcaaccgcg gcattcagcg cgaggatatt agtctggaag
    33721 gcaataccgt cgataacgct gataatgtcg gcaattttct tcgaactatc ggcgatctca
    33781 tgcatcgttt tcactacgcc atccaccact ttgccgccgt gctgggcggt gtcggaggca
    33841 ctttgcgcca gttgcgaggc ctggcgggcg ttatcggcgt tttgcttcac tgtcgcggtg
    33901 agctgctcca tgctggcggc agtttcttcc agcgcggatg cctgctgttc agtacgggag
    33961 gaaagatcgg tgttgcccgc cgcaatttca cgggtaccgg catagatggc atctgaacct
    34021 tcgcggacat gagtgacggt gtcagtcaaa gagcgttgca tatgtgaaac gctctgcgcc
    34081 aggtcgccca tttcactgcg cccgtcaatg gtcagggtat tcgccaggtt accaccggcg
    34141 atttcgcgaa tgtgagcaat aatttttgcc agcggagtaa gcaacatacg gcgaatgccg
    34201 taccacgcca ccagcagaat caataccacc accagcgcga taaccgccag ttgccactgg
    34261 gcaaatcggt aatcatctgc gttgtcagtg acgatatcgc gatacagttt ttcactgctg
    34321 agggcgtact gagcaaacgc ttcgcccatt gcattttgca ttccctgggt tggctgagcg
    34381 aaataagctc cagtattgcc ataatcaaga taatcaatca gttcagttaa cgctgtgtga
    34441 tagtttttat atttttcatc aatattacga ctggtagcga ccatttcagg taacggtgcc
    34501 atgcttttga attttttata atgagtcgcg gcctgggcca atgttttcct ggcgctatcg
    34561 agcaattcaa ctttggcgtt actttgttga ttggaggaat ccatcatcat ccgcaccgct
    34621 gaacgactca ggttaatgcg cgtttgcagc attaaatccc aggttgacgt cagctcgccc
    34681 tgctgttccc gtaattgatt ggaaaccaca aagctcttct ggctatggtg aagggaagaa
    34741 aaaaacagac tgccggaaat aagctgtaac agtgcgaata cccccagcac cattaccaac
    34801 agcgtgacta cgcggatacg gttaatcata aggcaccttc ctgaaaacaa gttaatctcg
    34861 ttatcggcaa gaagggggga aactttattg ctgatgccac ccgccgcgaa attgaaataa
    34921 aaaacccgat gcgcagatca tcggggtcat ttcaattgag gaaatcggga gaattacgcc
    34981 acttctgacg ccgcgctatc taacagcgcc atctcttcgc tgttcagcag tttttcgatg
    35041 ttcaccagaa tcaacatccg gtcgcccagt gcgcccagtc cagtgagata ttctgttgaa
    35101 agcgtcacgg caaactctgg tgccggacga atttgctccg ccgtcaatga aagcacgtct
    35161 gaaacgccgt caaccacgat gccgaccacc cgctgtccga gattcaggac gataactacc
    35221 gtgttgtcgt tatagtccac atccacctgg ctgaacttaa ttcgtaagtc aacaatcggc
    35281 acaataacgc cgcgcagatt cgtgacgcct ttgataaacg ctggcgtgtt cgcaatccgt
    35341 gttacctgat cgtagccacg gatctcctgc actttcagga tatcaatacc gtactcttca
    35401 tcaccaaggg taaataccag aaattcctgg cctgacggct cgctggccag ctttgttaca
    35461 ttcgtcatac cggtcatatt gttacctttt tactcattca ggcggcggtg ttcgccatac
    35521 gttgttcgcg gtttatcgcc tgcaaggcgg agacatcaac aatcagtgcc acgctgccgt
    35581 cgccaagaat ggtcgcagca gaaatgccgg ggactttgcg atagttactt tcaaggtttt
    35641 taaccacaac ctggtgctga ccaattaatt gatccaccag caaggcgtag cggcgaccgc
    35701 cactttgtaa gatcaccaca attccctggg tggcttcggt tttcgcgccc gcgacgttga
    35761 acactttcca cagttcgacg atgggcagat attcaccccg cacttccagc acccgctcgc
    35821 cgccggccag tggatgcaga tcggcttcac ggggttgcag tgattccata acagcattca
    35881 gcggcagaat gaaaacttca tccgcaacgc gtacggacat gccgtcgagg atggccagcg
    35941 tcagcggcag taaaatgcgg atcgtagtgc cagtaccctg cttcgactgg atttcgacat
    36001 gaccgcccat ctcctggata ttacgtttaa cgacgtccat gccgacgccg cgcccggaga
    36061 cgtcggtgac ctgctctgcc gtggagaagc ctggtgcaaa tatcagcatc gcgacttcgt
    36121 cgtcgctcat gttttcgctg acagtcaaac cttgcgaggc cgcttttgcc agaattcgct
    36181 cacggtttag ccccgcccca tcgtcggtca cttcaatgca aatgttgccg ccctgatgtt
    36241 cggcagacag aattaaattt ccgacgctgt ttttacctgc ggcgagccgt ttttctggca
    36301 gttcaatacc gtgatcgagg ctattgcgta ccaggtgggt cagcgggtcg ataatgcgtt
    36361 ctatcaggct tttgtcgagt tcagtagaac tgcccaccag cgtcagttct acctgcttgc
    36421 cgagttttcc cgccagatca cgcaccagcc ggggatagcg actaaaaaca tattccatcg
    36481 gcatcatgcg aatcgacatc actgattcct gcaaatcacg ggcgttacgt tgtaactgcc
    36541 ccatgctggt tatcaaatca ccatgattaa ccgggtccag ttcgctggaa cgctgggcaa
    36601 gcatggactg ggtgataacc agctcgccga cgaggttaat taattgatca accttttcta
    36661 ccgctacacg gatgctggtg gattcattgc tgcgcgtcgt tttttcccgc tccacgcggc
    36721 cggttggcgc ttgttcggct gccagtttaa gcactggtgg ggtggatatt tttggcgaga
    36781 cttctactgt ttcaaaggta atctgatcgg cttcaatcac aaaacagagt accgctgtga
    36841 tgtcatcttc ggcgatgtcg cccggtaata ttgccgagag cgaatccgcc cctttcacca
    36901 cgtcagttaa cgttgtcaga tgtcccagtt cttcttccag caggtcgact tccccggcct
    36961 tcaggcgcga aaggataatt cgtcgcggcg actgactgcg actctgctca tcttgcggtt
    37021 cacttttggc aaccacactt aatcgggtca ctgcggatgg cgtttcgcct ttcgcttcta
    37081 atgccagttg acgcaaggcc tggcagatat aatcgaagct ggcggcatcc ggctcttgcg
    37141 actgtttata agcgtcgagc tgttcttgca tgatgtcctt cgtttccaaa aacagattga
    37201 taatgtcggt gttgagttgc atctcacctc gtctggcttc atcgagcagg ttttccatca
    37261 gatgcgtggt ttcctgcaaa acgctgaagc caaaagttcc tgcccctcct ttgatcgagt
    37321 gggcagcccg aaagatggca ttcaattgtt cggcatctgg cgcttccggc tgcaaaacca
    37381 gcagatgctg ctccatgtca gccaacagtt cgtccgcttc atcaaaaaat gtctgataaa
    37441 aatcgcttat atccatgctc acgctgtcac ctcggttcgg ctgatggcat tgtgggaaca
    37501 ctgacctgtg gtgcaacctc aggtttttcc agggcgctta ctggctcatt ctggctttcg
    37561 gcgttttcat gcaaaatggc ctgttcggct tgtttgttca gtaccagcag gctgatgcga
    37621 cggttgacgg catcatcagg tccgcgatcg cttaagcgca tcgttgccgc catgccgacg
    37681 acacgtaaca ctttgccgct atccaaccct ccgaccatca gttcgcggcg ggatgcattg
    37741 gcccgatcgg cagaaagctc ccagttgcta tatcctttct caccgctggc gtaggggaaa
    37801 tcatcggtat gacctgaaag gctaatacgg ttgggaatac cgttcagtac aggcgcaatg
    37861 gcacgcagaa tgtcgcgcat atagggttcg acatcggcac tgccggttct aaacatcggg
    37921 cgattctggc tatcgatgat ctgaatacgt agaccttcct ggaccagatc gattttgaga
    37981 tggggacgta acgcccgcag tttcggatcg gactctatca actggtcgag atcaccccgc
    38041 aatttccgca atcgactttg ctccatgcgt tttttcagct cttcgatgtt cggctgctta
    38101 ttcacttccc cctggctttg ggtgtaatca tcaccaccgc cgggaattgg gctttcacta
    38161 ttagaaatgc gatcgccgcc cgtaaccgca gtcgccagtg gagtccggaa gtactccgca
    38221 atctgaatca gctcttttgg gctggagatg gagatcagcc acatcaccag aaaaaaggcc
    38281 atcatcgcag tcataaagtc ggcataagca atcttccacg atccatgtgc tgccccgtgg
    38341 cttttggctt tgcgtcgttt gacgacaata atcggatgcg cttgattctt catgcttcct
    38401 cggttgtcgt ctgttgttgc ggatttttca ccgcacgcac atgctcttcc agttcaataa
    38461 acgacggacg ttcgctggaa tagagcgttt tgcgaccaaa ctcaacggcg ataggcggtg
    38521 cgtaaccgtt cagattagaa agcagagtga ctttgacgca ctgcatcatt ttgctggttt
    38581 cggcgctttt ctgacgtaaa acactcgcta atggggaaat aaatccgtaa gccaataaaa
    38641 tgccgaggaa agtccccacc atcgcatgtg cgataagcgc acccagctcg gcggcaggac
    38701 gatcggctga acctaacgcg tgaacgaccc ccattacagc cgcgacaata ccaaacgccg
    38761 gaagtgagtc cccgaccagc gccagactgt tcgccgggac ttctgcctcg ctttcgtgcg
    38821 tctcaatctc ttcatccatc agggcttcga tttcgaaggt gttcatatga ccgctgataa
    38881 tcagacgcag ataatcgacg ataaaatcaa gcatgacgct atccgcgagg atgcgtgggt
    38941 agctggcgaa gatctcgctc tcacggggat tttcaatatc acgttccagc gaaaacatcc
    39001 ccatctgccg cgatttcgcc atcaaccgat aaagcagagc cagcagatcc atatacattg
    39061 ctttggtgta tttggagcga cgaaacagca acggcagcgc cttcagcgtg cctttaatcg
    39121 ctttgccatt attgccgacg ataaacgacc caatccctgc accggcaata atcaccagtt
    39181 cagcgggttg atagagtgct ccaaggcttc caccggtcat caaataaccg ccgaaaactg
    39241 taccgagaac aaccaggtaa cctaataaga taagcacgac atcatccttc cactgttgac
    39301 catgacagga tgttcagtcg tcaggcgtta acgcgcgatt ggggcaaaaa aaagcagcgg
    39361 tacgtcgtta ccgctgctgg aatgttgcgc ctcaccgtat cagttaaaca gcctgtactc
    39421 tctgttcatc cagcagttgt gggataatat cggcaggatt ctgggaaagt ttacgtcttt
    39481 ttactgcccg ggatggcggt tgacataagc tgcaggcaaa gctgccaaca ggctggtgag
    39541 cgtgggtaat aaaattgccg ccgcagcagt tgcagctgga aagttgcagt aatccacttt
    39601 caacaaaccg caccaatgtc caggcacggg ttaatgccag cagtggtcct tcttctgctt
    39661 gtgggcactg ttcaaggtat aaacggtagg ctttgatcac cgcatcgacg ccattacaca
    39721 aaccggtttt cagtaaaaac tgccatgcat tacagaacat cgaagcatga acgttttgtt
    39781 cccaggtcat aaaccagtcg gttgagaatg gcagcatgcc tttcggcggt gggcttccgc
    39841 gcagttcttt ataaagtttt atcaggcgtc cgcgacttaa ctgtgtttcg ctttccagca
    39901 tctgcaaacg agcgcccagg gtgatcaatt ccattgccag ctgaatatcc cgcgcttcct
    39961 gaacaatgct tttttcactc atgatcaggc ccttttcttg cgcagcgctt cttcaggctg
    40021 attaacatca ttcagcaagc gtgttgagag catgatgccg gtatgaattt gctggagatc
    40081 gtcaacgcgg gaatcttgcg tcaactgagt aatcgtctgg tggctgtcaa aacggaagtg
    40141 acaaaccagt tgattggttt ctgccagctt aaccatttgc ggaagagtca gtgccgctaa
    40201 cgttgtcgcc atttcttcat ttatgccgag acgaaacata gcggacgctt tgtcctgaac
    40261 aatcaaacgc tgtgcaagta gtaaatatga caagttgatg tcataaatgt gtttcagcaa
    40321 ctcggaggta tgcattattc ccacccagaa taaccaactt tatttttatg cggtttcacc
    40381 gcaccccgtg atgtcgccgg gaagccccgg taaaaaataa ttagcattag aatagttgcg
    40441 ataagctgca ataagcagaa ccaccttttt ggtttaatat gtccttacaa atagaaatgg
    40501 gtctttacac ttatctaaga tttttcctaa atcgacgcaa ctgtactcgt cactacacgc
    40561 acatacaacg gaggggggct gcgattttca ataatgtgtg atgcagatca cacaaaacac
    40621 tcaattactt aacataaatg tataagtcat acttttgttt tgggtgtatt tcaatctgtt
    40681 aaaaagtttt tcgctacgct agcaagcaaa aatgaaacag gaataatcga aatgggatgt
    40741 tgcgcacact taaaataact caccgtaaat aatcatctgc tataaataat cactttcatg
    40801 caataccaga taagctattt ttaaacagac acttaccgca caacaaacta attaaataca
    40861 aagaaaggca acaatcaact taatgttaat gaaatgtttt acatatatta accacttgtt
    40921 taatgcggag aatcagtaca ctattttctt ataattacat ttgaaattat atgatcaccg
    40981 ggagtgattg attaattgtc tttactaata atcagactaa tatttacctg tttgaccgag
    41041 ttgggattgc gtcgtttctc cattaggagt aaagctttaa tgtcacctga agttcacaga
    41101 ataaggaaca ggttatgagc tatagcaata ttcttgtcgc tgttgcggtt acaccggaaa
    41161 gtcagcaact gctggcaaaa gcggtatcta tcgccaggcc agtaaaggga cacatcagtt
    41221 taattactct cgcttccgac ccggaaatgt acaatcaatt agccgcgccg atgcttgaag
    41281 atttacgcag cgtgatgcaa gaagaaacgc aaagctttct tgataagtta attcaggatg
    41341 cggggtatcc cgttgacaag acgtttattg cctacggtga gttaagcgaa catattctgg
    41401 aagtatgtca caaacatcat ttcgatttgg tgatttgcgg taatcacaat cacagtttct
    41461 tttcgcgagc atcctgctcg gcgaaaagag ttattgcctc aagtgaggtc gatgtgctgt
    41521 tagttccact tacgggagat taaccgctcc tacgcaagct ttggaaaggt agcaacttta
    41581 tcgcgctgct ggctttccgc gcttcgcgga actatctgct ttaggtcgct aatgaagcac
    41641 tcctgccagt ggttaatatc gtttttcacg ataacgtcca gcatttctgc atgacgggaa
    41701 atacgttccg ccagcgacat agtcaatgca cgatccagcg cagctgcaac ttcgtcacga
    41761 tcgtaggggt taacaattaa cgccgacgtt aactcgtttg ccgctcccgc aaattgcgaa
    41821 agaacaagaa cgcccgggtt ggctgggtcc tgagcagcaa catactcttt tgctaccagg
    41881 ttcatcccgt cacgcagtgg cgtcactaag cccacgtcag agtagcggaa tattttcatc
    41941 agtaatttac ggtcaaaatg ctgattcaaa taataaagcg gcgtccagcc taattgcccg
    42001 tatttaccat taattcgtcc agcttcattt tcgagctgat gacgaatatc ctgataggct
    42061 tgcacatcac cacgcgacgt tggtgcaatc tgggtataac gaattttacc atgatgctgc
    42121 ggatattttt ccagcaacgc ttcataggcg agaaaacgct ctggcaaacc tttggaataa
    42181 tccagccgtt cgacagaaaa gatattttgt acgtttttca gttccgcttt aagttgcgcc
    42241 agttttggcg gcagtggccc ggcagcctgt ttggctattt ctttcggttc aatgccgatc
    42301 gggtagactt ctgttcgaaa tgctttgccc caggctgtat ggctttttgc gctacgtgtc
    42361 gtgacgcggg tcaggttaga aagacaatcc aggaacgcca gacgatcgtt ttctgtctgg
    42421 aaacccagca aatcataatc acaaagctgt tcaagcaagg tgtcatatgt cggcagcgcg
    42481 ttgaagattt ccggtgtcgg gaaaggaata tgcagaaaga aaccaatgcg attattcact
    42541 ccccgtttgc gtaattcatg cgcaaatggc aacaggtgat aatcgtggat ccagataatg
    42601 tcatcgtctt gcaacagcgg cagtaattta tctgccagca acgcatttac gcgtagatag
    42661 ccgtcccagg caggacgctg aaattgcacc agatcgagcc gataatgaaa agcgggccag
    42721 agaacggcat tggagaattg gttgtagtat tcgtcaaggt cctgttcgct gaggttaaaa
    42781 gaggcccacg taatgttacc ttttttcacc ttttttagcg gctgatcctc attccctgtt
    42841 tcaccactcc agccaaacca cagtccgcct gcggctttca gtgcccccag tatgccaacg
    42901 gcaaggccac cggcactggc ggcgtgctcg tctggtggtg caatccggtt agatactacg
    42961 actaaacgac tcatagtcat cactcctgtt attttctctt ttttgttgta atgcggtggt
    43021 tatcatttca agccagctcc agacatccgg cacacccgcc agtcgccatg atgcctgagt
    43081 tgcacctgtg ccaattttta ctgacattcc gcccagtcgg ttaacgactg cgaagccaga
    43141 ttcatcggtt aaatcatcgc ccagaaatac gggcgttcgc ccgataaagg gagcttcctg
    43201 cataaaagct gcaattgcct cacctttact ggtacctctc ggtttgatct cgacaacaca
    43261 ctttccctgc tgtaacgcca tttgtggcca gatctgagta atacgttgcg ctaatgtcat
    43321 taatgcgtct tcatgctgcg gagcctgacg ataatgcagc gcaaaagcca tccctttcgc
    43381 ctccagctcc gcgccgggat actgagcgat gactgtatgc agttgcacgc taatatcacg
    43441 cgcaatcgca tccggcagat gaacgatatg tgttttacca ttgatgtcac ggcgctccgc
    43501 cccatgcacg cccgctaacg ggaagcgata aggttttgcc agtgcgtcaa gctccaccat
    43561 tgagcgccct gatatcaatg ccaatgcacc atcacttgcg gttgccagta gctgtagtcc
    43621 ttgcagaata ttgtcaggca cgacgacctg atcgggatgc ggtttgattt ccgccagcgt
    43681 tccatcaaga tcaaaaaacc aggcatattt cgcggatagt tcaggggttt cggttaacgg
    43741 ttctgtcacc cggctctcct ccttctcttt tcttattgtt ttgcgcagaa cgcgctttac
    43801 agacatgtaa gtatagacag tgtgacgggg gtcgccattt gcaatgaaga acagccaacc
    43861 gttgtggcgg ctggctgtgg tgggaaaaaa cgttaaattg ttgtggaaaa aagcatcaga
    43921 cagtgcgttt cgctttttgc ttgtaacggt cgaagatcac cgctgccagc aggattaagc
    43981 cgcgaaccac gtactgcgcg aaaggagaaa tattaagcag gttcatggcg ttttccacgg
    44041 tgcctaaaat taagataccc gccaccacat atgagatttt tccgatgcca cctttcagag
    44101 aaacgccacc taaaacgcag gcggagataa caataagctc ataaccaatc gacgtcattg
    44161 gctgcccact agtcatacgt gaagccagaa taattccggc tatcgcagat accaggccag
    44221 agagaacaaa gataataatt ttggtgcgaa caaccggtac acccgccaga cgcgcagcct
    44281 cttcgttccc gccaatcgcc agggtgttac gaccaaaggt ggttttattc agcaacaaac
    44341 caaagataat cagacacgcg acggtgagcc agattggcgc aggcagaccg aaccagttag
    44401 cgtaaccaag ggcaaagaag ctttcatctt cgataccgac cgctttaccg tctgaaatga
    44461 tgtacgccag acctcgaaca atctgcatcg ttgccagtgt tgtgatcaga gcatttattt
    44521 tcagtttggc gataacaaag ccattgacca ggccacagag aatgccaagc agcaaccccg
    44581 ctgccacgcc aatccacagg ctttcagtca ggttgataac caccgccgtg gtgacacccg
    44641 cacaggcaat tacggaggcg acagaaaggt caaagtcacc ggaagcaagg cagaacaaca
    44701 tgccacacgc caccatcccc gacatggaaa ttgccaggcc caaccctttc atattaatga
    44761 aggtggcaaa atttgggaca aaaatggcac aggcgataaa gagcaccgca aacaccacca
    44821 gcatgccgta ctgatcccag atacgcccga agctgaatga cgacttaggt gcgccagacc
    44881 ccgatgtaga aacagaagac atcatactct ccttactcag gcaactgcct ggctgacttt
    44941 aggcatcgca aggctcagtg cctgacgctc atctgcctgc tcgtgtaaca attcaccggc
    45001 gatttcacct tcccgcatca ccacaatccg gtcggcaacg ccgaggactt caggtaagtc
    45061 gctggaggca aacagcaccg ccacaccctg cgccgccagc gcataaatca cgttgtaaat
    45121 ttcatgctta gcaccaacat caatgccgcg cgtaggttca tccagcaaaa tgaccttcat
    45181 ctcttccgat aaccagcggc ccagaatggc tttttgctga tttccgcctg agagattcat
    45241 gatcagttgc tcagcgcccg gcgttttgat gttgagcgaa cgaatgtggt gatcggcatt
    45301 gttttcttcc caaccgttgt tgattacaca accgccgagc acatgtttac gtctggcact
    45361 gatgttgata ttgtcgcgaa cggagtgcac gggaataatg ccttccgctt tgcgatcttc
    45421 cgggcagagc atcatgcctg cggcaatggc gtggctcggt ttacgaatat cgatcggctg
    45481 ttggtcgata taaacctgac ctgcggtgat ttgcgtcccg ccaaacaagc ctttcattaa
    45541 ttcgctacgc cccgccccta ccagaccaaa cagcccaaca atttcaccac tgcgaaccgc
    45601 cagacttatt ggcgtacgca cgcctggtgc tttcacagca tcaagacgca ggcgctcctc
    45661 gccataacta cgaggttgcc agccgtagat atcgccaatg tcgcgcccga ccatcgcctg
    45721 caccagcgcg tcgtggtcaa cctgctgcat atcggtaaag gttttgacat aacgtccatc
    45781 tttaaagaca gtgatggcat cgctgagggc aaatatttct tccatacggt gagaaacgta
    45841 taagatcacc cgcccctctt ttcgcagttc acgaataacg cggaaaagat tgtcgatttc
    45901 gcgggcagaa agggagctgg ttggctcatc aaaggcgata attttagcgt tacgcgccag
    45961 cgccttggcg atttcaacca tctgccactg accaatggag agatatttca gcggcgtgtc
    46021 cgggtcaata tccataccaa gatgtttaag ttgtaaaccc gcctcataat tcagcaatga
    46081 gcgattcaca atgccgcctt tatgcggcag ctggccgaga tagatgtttt ccgcgacggt
    46141 catttccggc acgagatgta gttcctggta aataatcgcc acacccgcgt taagtgctgc
    46201 ggtcgtgtcg gaaaaggaca tttcctgccc attaatcact acagaacccg tggttggcgc
    46261 atagttgccg ctgaggattt ttaagagagt tgattttcct gcgccatttt cacccatcaa
    46321 cgcatgaacc tgaccggcat agcagtcaaa actaatatcc gtcagcgcct taacgccggg
    46381 aaacgtttta ccgatgccgc gaaatgagag atacggggta gactgttgca taacgtctcc
    46441 gtgaatcact ggtcgttcac accccctctg catcatgcag aggggaattt ttccggcaaa
    46501 ttacttaccg cctaaacctt ttttctccag ttcttcttta aagttgtcac gcgtgatcag
    46561 taccacgtcg gtaacttcgg taaattttgg cggttcaacg tcttttgcta cccagttgta
    46621 aagcatttcg ctggatttat agccatgtac gtccgggctt ggcagcaggg aaccgtagaa
    46681 gccggttgcc tgtgctttag acagttcgct caccgcatcc acaccgttaa tgccaatgcc
    46741 gatgatatcg gccgctttaa agccctgacc ttccgtcgcg cgtacgccgc ccagcacggt
    46801 gctgtcgttc ataccgacga tcagccaatg tttaacttcc ggatgttgaa ccagcattga
    46861 gttggcagcg tcaaatgccc ccgggatgtc gttagatttg gtaggtacct gataaatttg
    46921 tttttccggg aatccggccg ctttcagcgc atccatagat cccgtagtac ggcggcgggc
    46981 ggtatccagt tcgttggcgg taatctccat caccgcgctt tctttgacat cccagccacg
    47041 tttctgcatc tctttataca gttcctggcc ctgacgttcg ccaattttag tcgccgccat
    47101 catcaccagc ggaacggtat ccattggctt acctttggcg ttaacaaact ggtcatccac
    47161 ggcaatgact tccatatcgt agccacgcgc tttcgcgacg atggcagagc cgagtttggg
    47221 gtccggagta caaataacga aaccttttgc gccactggca gccaggctgt cgatcgcgtt
    47281 caatgttttt tcgccatccg gcacggcaat cttaataacc tcaaacccta aatccttccc
    47341 ggctttatcg gcaaacttcc attcggtctg gaaccacggc tcttccggtt gcttcaccag
    47401 aaaaccgagc ttcaggttct ccgccatagc ggattgtgac ataacggctg ccagaccaat
    47461 ggctgccagg gctttagtaa atttgtgcat ggttctctcc agctttagtg tcgttttgtg
    47521 tagggcaaaa acgaatgaca ttcgttaaat taatcggaaa acaaagcatt accttttaac
    47581 taaaagataa gtgactgtgt tgacatagtt ttagcgagaa attaattctc cataggagag
    47641 caatatcaca tcgcagaatt acagtgagaa cgtgcataaa tttagcggga aaagacataa
    47701 gggaaagcca atttgtcaga caaattgtcg aatgcacagc agattaatcc ataagattag
    47761 cctggaaatc cttgttgtct ttggtaccca tgcgggatgt cttcttttta accagtcaat
    47821 aggccgcatt acctggcgtt gagtttttga aatggtgtaa taaccgcaac tcaaagatgt
    47881 ggaaaatgca cgtcattcat ttcgccatta attatcactg tgctcattaa ttaacagaac
    47941 acgtataatg agagccatct cgcaaaaatg aaaaaacgtt ttataaaatc atcacttcat
    48001 catgaattca aattcattga ttaatatcaa caagatacaa aaagcgctat cattaaaatt
    48061 cattgcagtt acattgattt catcaatgaa atgtaaaaat atataaactt gatgatttaa
    48121 gcattttctt atacccgttc agacgttatt cttatttcag atcatcgtca gaattgactc
    48181 cacgatcaca tttcggaccg gcagaaagga attattctgc aaacagtaat tatggtgttt
    48241 tgatttatct tgcacctctc cacttctgga tataaggata ttaggtatgg caaccgctgg
    48301 aatgcttctc aaactcaact ctcaaatgaa ccgcgagttt tacgcatcca atctctacct
    48361 tcacctgagt aactggtgtt ctgaacagag tctgaacggc accgccactt tccttcgcgc
    48421 ccaggcacag agtaatgtga cccaaatgat gcgcatgttt aactttatga agagtgtcgg
    48481 cgctaccccc atcgttaaag ccattgatgt tcccggtgaa aaactgaact ctctggaaga
    48541 actgttccaa aaaacgatgg aagaatacga gcaacgttct agtacgttgg cacagttagc
    48601 cgatgaagcg aaagaactga atgatgattc aaccgtcaat ttcctgcgcg atctggaaaa
    48661 agaacagcag catgatggtc tgttgctgca aaccattctt gatgaagtgc gcagtgcgaa
    48721 acttgcgggt atgtgccctg tgcagaccga ccaacatgtt ctgaatgtcg tgtcacacca
    48781 gctgcattga tcatcatcgg cgctaatgca ttgcgccgat gaaggttttg agaaaccgct
    48841 gcctcatctg tttgaagcag cggttttttt aatgggattc accctgtggg gtaaacttga
    48901 gttcaataag cgcgatggct ttttggattg cccgcatggt gaccgggtct gcggcggcgg
    48961 gatggttagt aaagtcgata ttcttcagct gactggacat tttttcacga acttcaacgg
    49021 gcgcgattac atcgagaaca tccagaattt gtttgataac caactggcaa gcaaccacat
    49081 cagaaaccag ttcctgatcg gcattcagcg gctgggacat cgtaaactcc tgatagcatt
    49141 ttgaaagccg ttatagtagc ggcttcacat cttcagcgat agtcacatcc accgtcatca
    49201 ggacacaaaa aacctgccgg agcaggtttt ttattatcgg aacatattgc ctggcggtac
    49261 gtctttgaac gtcttgcaat agttattgaa catacttttc aggattttac gcagtttcat
    49321 cgcggcactc cgaccatttg ttatacaggt gttattctct ttgcgcttat aatatgacaa
    49381 ccatcacaaa aatcaatctt tatgtgatac aaatcacata aacacccctt taatgttata
    49441 aaaatgataa tcaaaaaaca gcccccctat ttctgacacc tacagatggc aagaaatagc
    49501 gcctgccagg cgtcttttcc ggccattgtc gcagcgctgt aacgcgtaaa atagtgcttt
    49561 ctcttactct tctggctgga ccatgagact tctgattctg actctttcat taataacgct
    49621 ggcggggtgt acggttactc gccaggccca tgtgagcgaa gttgacgcgg caacaggtat
    49681 tgtacggttg gtttatgacc aggctttttt gcagcatgcc cataccgatc gttatgtcag
    49741 tcgcgggatc gccgatcgcg catgccagca ggaaggctat acccacgcgg tcccctttgg
    49801 tcagccagta ggcaactgta gcctttttgc gggttcctta tgtttgaata cggaattcac
    49861 tttgtcatat cagtgccatc attccgcctt ccctgtcttt ctctaaatat tttaatcagc
    49921 gaggggatct tcgctgatta aagaaatagc ggtaatgcgt tttattccca ttcgtatttt
    49981 taataattga agtttatatt ttaccttttg caaataataa aataacaaat tatagtgacg
    50041 ccacagcaac aaatataacc tttgtggagc actatcatgc tgaaaccaga aatgattgaa
    50101 aaacttaatg agcagatgaa cctggaactg tactcttcac tgctttatca gcaaatgagc
    50161 gcctggtgca gctatcatac cttcgaaggt gctgccgcgt tcctgcgccg tcacgcccag
    50221 gaagagatga cgcatatgca gcgtctgttt gattacctga ctgataccgg caatttaccg
    50281 cgtattaata ccgttgaatc tccgtttgct gaatattcct cacttgatga attattccag
    50341 gaaacctata aacacgaaca attaatcacg cagaaaatta acgaactggc tcatgctgca
    50401 atgaccaatc aggactaccc aacatttaat ttcctgcaat ggtatgtttc tgagcagcat
    50461 gaagaagaga aactgttcaa atcgattatt gataaattaa gcctggcagg caaaagcggc
    50521 gaaggtctgt attttatcga caaagaactc tctaccctcg acacacaaaa ctaatgctct
    50581 caggcggcag gttttctgcc gccgtttcaa atcagtgacg gcaaatctta ctctgatcgg
    50641 tcgaaaaacc ttcttctgaa ggtataaatt tgccttttgc tgccagaaac gctaccagct
    50701 ctcccgcagt catcccttct gccgagcagg tgtgaaaacg tgcctgttca ccaaaacgcg
    50761 ctttaattgc tgcttccaga ctggcatgcg tatattgctc gcctgattca atcatcatat
    50821 ttaacacttc atgaccgtga atagagtcca tcgtccctcc tcaaaaaaag cctagcgtag
    50881 cgattgccgc ttatgaagac tttgcgccag cgcaggactg aatgcttttt attgtacatt
    50941 tatatttaca ccatatgtaa cgtcggtttg acgaagcagc cgttatgcct taacctgcgc
    51001 cgcagatatc actcataaag atcgtcagga cagaagaaag cgtgaaaaac agaaccctgg
    51061 gaagtgtttt tatcgtggcg ggaaccacaa ttggcgcagg catgctggca atgccgctgg
    51121 ctgcggccgg tgttggtttt agcgttacgt taatcttgtt gattgggctt tgggcgttga
    51181 tgtgctacac ggcgctatta ctgctggagg tgtaccagca tgttccggca gataccggtc
    51241 ttggcacgct ggcaaaacgc tatctgggac gctacggtca atggctgacg ggcttcagta
    51301 tgatgttctt aatgtatgct ctgactgcgg catacatcag cggtgccggt gaattgttgg
    51361 cctccagcat cagcgactgg acaggtattt caatgtcggc aaccgctggc gtgctgttgt
    51421 tcacttttgt tgccggtggc gtggtttgtg ttggaacatc gctggtcgat ttatttaacc
    51481 gttttctgtt cagcgccaaa attatttttc tggtggtgat gctggtattg ctgctaccgc
    51541 atattcacaa agtgaatctt ttaaccctgc cgttgcaaca ggggctggct ctgtcagcaa
    51601 tcccggtgat ttttacctca tttggttttc acggtagcgt gccgagtatt gtcagctata
    51661 tggatggcaa cgttcgtaag ctacgctggg tgtttataac cggtagtgcg atccccctgg
    51721 tggcatatat tttctggcag gtggcaacgc ttggcagcat tgattcaaca acctttatgg
    51781 gattgctggc taatcatgct ggattaaacg ggctgttaca ggcgttacgc gaaatggtgg
    51841 cctctccgca tgttgagctg gcagtgcatt tatttgctga tttagccctc gccacgtcat
    51901 ttctcggcgt tgcgttaggc ttatttgatt atctggctga tttatttcag cgttcaaata
    51961 ccgttggtgg acggttgcaa actggtgcaa ttacctttct gccgccgttg gcgtttgcac
    52021 tgttttatcc acgaggattt gtgatggcgc tgggttacgc cggtgtggcg ctggcggtac
    52081 tggcattgat tatcccttcg ctgttgacct ggcaaagcag aaagcacaat cctcaggcgg
    52141 gttaccgggt gaaaggtggt cgtccggcgc tggtggtggt gtttctctgt ggtattgctg
    52201 tgattggcgt gcaatttttg attgcggcag ggttgttacc agaagtgggg tgatcagata
    52261 gcctcaaatt ccttattggg tgccagaatt aacgctgaca cccaatttga cctcttaatg
    52321 caggcagcac tgcttaaatt tcttaccact accgcacggg caaggatcgt tacgccccgg
    52381 tttctcttct gctttgatcg gttgctgaac agctttttcc tgcggatgcg ccatccagta
    52441 cgcatgtaga tcaagcgccg ccagtcgaat ggcatctacg ctctcttcaa acgcttctgg
    52501 cgacattttc tctacccgct cgaagttttc ctcagtaccg tgcagcgcaa tcgcctccag
    52561 cgctggtttt aacgaatcgg gcaacgttga ccagtcagaa agtgccacgc cccgcatata
    52621 gccaaagcac cactcctcaa caatcgtcag ctcgctgcca tcaacttctc gcaagccgaa
    52681 taacggctca aactgctccg ggaattcgtt cagacgctct gcggtatcgg ccatatgttg
    52741 aaaagccaga ttcataaagc gcgtcatctc tttctctgac gcccagcgcg gcacatagtc
    52801 agccccaccc cacacggcaa ccagccactg ttccggttca atctcttgcg gagaactcaa
    52861 caccgccgtc aataaaccgt ccagctccgc cacatcaagg atggcgtggt cagtgttgta
    52921 tttggtcaga atatcgtcca gccattccaa ctcactttcg tttaacggtc ccgttttcat
    52981 acgcttttcc ttgtggatct caactcgcca gcacctatct tacatgccgg tccgtatcag
    53041 agatactttt tgagtggctt tgctggtgat taaaaattag ggagggtgta acgacaagtt
    53101 gcaggcacaa aaaaaccacc cgaaggtggt ttcacgacac tgcttattgc tttgatttta
    53161 ttcttatctt tcccatggta cccggagcgg gacttgaacc cgcacagcgc gaacgccgag
    53221 ggattttaaa aactatcaac caccatttat aaatcataac attatgattt tattaacttt
    53281 gaaaatggct ctatacaacg ccatttgaat ctattgtcac tttttatcgc cactttttac
    53341 cctctattgt caaaagggtt caattcaaca gcagcctcta aatgacctgg agcaaaatgc
    53401 gcataacgca tagtcatttt tatatcgcta tgccccagta ttttttgcaa cacaagaata
    53461 tttccgcccc gcatcataaa atgactggca aacgtgtgac gtagcacatg agttaattgc
    53521 ccatcaggaa gctcgatctt cgctctctta attgcagcgt caaaagcctc ataacatggt
    53581 gaaaatagcg ctcctcgttt tttgggaagc atagcctgca attgaggtga aatcggtaca
    53641 gtgcggttct tctttccttt agttttaaca aatgtgattc gaccgggcag tacttgagat
    53701 tgctttaatc cttctgcttc actccaccga gcaccagtcg caagcccaat acggacaaca
    53761 acccccaaat ctttattccg tgactcatca cacgcaatca gaaggcgttc aatctcatct
    53821 acatacagaa acgccagttc cttttcttcc tcacgaaact tgcgaatacc agtcaggggg
    53881 ttttcaccag accactcccc aaggcgcttc agttcggcaa aaacagcatg tagatatgac
    53941 tgctcgcgat taacggttgc ttcactaagt tttttcttcc ccttgggatt ccattctcct
    54001 gatagccttc tttcccgata agtggcaaac atatttttgt caaactgaga agcaaatgga
    54061 tctcccagcc tggaacaaat cgcctcaagt ttgactttgc gctctgcacc agaggacaag
    54121 gttttaccgt acatctcaaa ccaacgagca atcaactcag aaagacgagg accagaacca
    54181 tcttgaaact cgtctccaac tctactattc attaaacggc gctcataaga gagcgcctca
    54241 ctttttgtcg caaactgttt acgaatgcgt tttcccgatg ccccgtaggg ataacattcg
    54301 caaagccatt tacctgatgg aatcttacga accgacattt tagttactta tcacataaat
    54361 caaatgcagc cttagtgaca tcccccagac tcttttttaa ccctggggcg gcatcattat
    54421 ctagccaaaa tggattattg ttatctaacg gtaacgcacc aaatgtttta ccttttattc
    54481 gagccaaacc tgtaagtgca tataacttat tatcgtcaaa attcatcaca taaggattac
    54541 catcaagaca ctgtaattga acctcatcag aattaaatgg ccatacccca ttgaaactct
    54601 cacgttcaat agttttaaaa ggcattgcga cggcggaaaa agaaaacata gataaaaaag
    54661 taactaatag ttgaaccttt tttactttca tatcattacc tcaatttagc tcaagtaaga
    54721 ttacaaatta aaaaacgccc tagaaatgac accgcctacc aaaaccccta cgcagataaa
    54781 gaatattatt tcttttggat aaagtcggat taattctgaa gcacgaagtc ggacttctgg
    54841 taaggtcgaa ctctctgtgt ggcttgatgc cgattgttgc tctaaccacg acaatgcaga
    54901 ctgtaactga gaacgagtaa gatcgtttaa acgtcctgta ccgaaattga tatggcaata
    54961 ccgcagaagt ttttgtcgaa gtccacagtc ttcactgtta cgtagtaata aacttacaag
    55021 agccttacag gcatcatgat ctttacatcg ctcaagcatt gcatgcagaa aactctccgc
    55081 tgttttatat tgatttactg tcatatcatc aataccagct acaccaatct ccgcatgtac
    55141 tttttgccaa ataataaacg cttcagtatt gctagcttct gcaatagcag caaccaagct
    55201 atttagctcc ttacgctgag ccttaagcaa agggcgatcg tcatcatcat tattcgaagg
    55261 gattgcgata ttgacagtat gagaaccatc atatcgctct atctgaatat tcttttcgtg
    55321 aaaatcacgc ccagcaacgc gattgtttga accgtttgag ttgacggcca tgtcacctcc
    55381 ctactatcac ctacccttag tttcgttata gtcacgacca gcgatacggt tattaccacc
    55441 agaaatattt aactcacgtc ctgatggctg agtttccttt tcactgatcg caccttttaa
    55501 agccccaatc accgcgtttt tcacatctaa cgaagctgct cgaaagcgag taatcaactc
    55561 ctgctcatca tcgttataag tttcaggtga gtgaattccc aacacaacat actgaacatc
    55621 aaggccaaaa cgagacagcg ctgccaaata cgcagcatca ggaaagctat ctcctttctc
    55681 atatctaagc tgagttagct ttttgactcc accaatgtcg ctcatggcaa cttgactaag
    55741 tcccaatctt tccctttcct cacgcaaccg ctgaccaata tcatttttca tacaaaaacc
    55801 ttgataggta tcttttttga taccaaaatg atttcacgag ctattagatg atcacaatat
    55861 accactatga aacaagttct tcacgatacc agatcacgca ttccgcgtaa caccgccaca
    55921 ggtccaagac tggcacttcg gctgtccctt gaggagcgag ccgtcattga tgaaatggca
    55981 gctaaagaac aacgctcatc ctctaacatg gcgcgcatga tcttccttcg cggcctagag
    56041 ctaacccaga aagaacaaaa caaatcttcc tgatcaggag gctagtggga tgtcaggtat
    56101 aaccatcaat atcaatgtga atgcccccta tgtatccctg cagaaatatg cagagataac
    56161 aggtatccct cttaatacgt gcaaaaagat gttggctgac ggtcgaatta ttatccgccc
    56221 caaacgcgcc aaaatggaaa agcctgaagt aaaccttgtg gcgatgttaa aagacgcttt
    56281 ggctaacagc taaaacaatg aacagagcac catcatgaaa aaaaacgcta ataatccata
    56341 ctccaaattt cgtaatggcg tagaacgcca tgtacaccac gtcgctacca gtgcatcacg
    56401 tagtaacagt cgctataacc tgaacgagac gcacgcaaca ccggatggcc acgctgtaaa
    56461 acaaatcggc gagcatgcct ggctgattga gaaagctgga atcgtggtcc acaaatgccc
    56521 acgcaatccg tttaccggaa accgcatttt tgcattgaac tgcggcgaca atcacttcgg
    56581 gcaggatttc acattatacg aagcacttcg cacggttgat cgtctgcttc gcgggcaaag
    56641 ttttattaaa caggctgatt tataacaggt gctttatgac caaagagcat gcacaaggtg
    56701 tatttatccg ttttattgat tttcgcggtg aactgttatt acgcgcatca gctattgatg
    56761 gagtcgtccc atcagaaaaa aatgcagcta cttacgttta tctgaacggc acgcgcctga
    56821 ccgtagaact tccgtaccag actgtacacg aaatcattag cgaagctgaa aaggcacgtc
    56881 aggttaatgg cgataaaccc tatatcgaaa ttatctgcat ggattcagaa gctgaaattc
    56941 agaaagcaga ttaaagggtg ttgcaatgga caaagaatat aaaacactca tcaacaaagc
    57001 acttgagcgt ttttattttc gcttaagcgc atcaggcgtt catgctgaac gtgcagcccg
    57061 tgactcattg accagggcaa tccggagtct gtatgacgtg gctttttacg ctgatgatct
    57121 ggatgcactt aacgaacttt ccgagctgat ctgtgccgca gaatgcggag aacatattga
    57181 accgtataag ctggggaata tcgcatgagt atatttatct catggcttgt tctgattatt
    57241 tcggtggcct gcgccattgg gattatgcga attattaatt cagtgaaaaa gatcgagcgt
    57301 tttttctctg atgaataacg atacaaataa aacatcaaat taaataagaa aacgtgaaaa
    57361 ccatccgtat taacggaggt attcgcacac gcaaataacg gagatacaaa aatgcacgca
    57421 aaagaagaag gtatcatcag agcactgaaa gaaatttcaa agatggaaag cgaagtagcg
    57481 aaaaaagccg tggccaatgc tcacatggac gtcgcaaccc acacaatgat agtcgcaaaa
    57541 gtcacggcag aggctgccaa aatcatcgaa gaacagggtg tggaacttgc gcttctcaaa
    57601 actaaaccag tcaccggact ggatttatct gacaccggac gccttattta cactattggc
    57661 tcggagccac agcgatacac cattatcgcc ggattacaga acaaatacct gatcactcct
    57721 caccccataa gggaatcaac gcttctgaca aatctccgcc tgatagagcg ctctcaagtt
    57781 gcattcattg atgacgcccg acacaccgta tttaacgcat agggttactg gacaaagggg
    57841 gtgcaatggc aattaagcat tttcccgtcg ttcgctttac ctccagaggg cgcgaatacg
    57901 aggtcgacga acgcctgatt accactatcg acaaacatcg ttcggaaaag gatgcacacc
    57961 acatctacct cactgacggt acttacttct gcgccaccaa cgtggcgcgg gtgaatctta
    58021 tccgacaggt acaggagcca cgcagatgac cattctggac tacatcgcta ctcatccggg
    58081 ttgtagcggc ggagagatcg ccgcagcact gaatactcca accacagcca ttaatgctga
    58141 gttacgccaa ctttggcgcg gcggcttagt catcagaaca aaccgcagca caggtggtcg
    58201 cgctcgcaaa actggaggcc aggcttctta ccacgtaaac ccgatgccgt tcgggtgtag
    58261 caatccactt actcacatgt ttaaccagct actaaaggaa gccagaacat gagcaccatc
    58321 aaccaccaga agctacgcga actggcattt gccctgcaac gaatggcaac gcctcaaaaa
    58381 ttactggcat ttcgcgcaat gctctcgccg tctgctgtgc tggcactgct ggatgagctg
    58441 gagcacgcca gaaccacggc tcctgccatt cgcctgacac tccatcatga aatcgctgat
    58501 ttctgcgcga cgttggaggc accaggcgaa ccggaaacgc cggaagcaat acagcaagag
    58561 ctgctgcaac gcattgacaa ggtttttgat ttttttctga accagtaaga aaccagaaca
    58621 tgcacacaca aaaaaaccgc ttgccatgcc gcaatcagtc aggttacatt tccgctgcac
    58681 ctcataaaac gggtgccggg attctcaacc cgatacagag caaagcgcat aaccgcgcca
    58741 gcggtttttt tgtgcgtact gtattgccac gtctttttcg cgtcagaatt atggcggggc
    58801 gtacggggcc gacttcggtc gggccggatt ctttgctctc cggtgttgag aaccctgtac
    58861 gtctcgccac cccgagattc tcaactctgg atggtgagct atttctatca ccgagcaaag
    58921 aggccacacc atggcaaacc gcaaacaaca gcgcgcatac gctgcgcgtc gtcacatcca
    58981 gactgaaatc aaccgtagac ttttccgcgc atcacgcgtc gcgcaaatca tgcacatcaa
    59041 tatgctgcat gagcgcagcc acgcgctatc gaacatctat tccgcctctg ttttcagcta
    59101 tctggcggat gatctgcgcg agctgcaaca actcttccag tagcaaaaca aactccatta
    59161 attcctgttc cgggcctttc ctgcaccttg cggcgggagg ccttcgcaca tctgtagtaa
    59221 agagaattgc agcatgattg acgctcatga cttcacaaga tgggtgcgca cacaggacac
    59281 ccgtctggct cccgttcttc agggattatt tgatctctac atccgtggtc gtgacaacag
    59341 agcacgcacc acaaaaccag agaatgcaga caccctttat ttcacagtag acgactgcta
    59401 ccgcgtggac ttcacaccac acgggctggc gttgcactgc ctgacaccac acggagaatc
    59461 actgctggcg tattacgact ccccggcctc cgtatttgcg gcaatgctgg cgcatcgcac
    59521 tgctggcggg tgtgcctcgc tgagtgaata caccgctgaa tttaaccgcc tttctgccct
    59581 cttctcgcag gagtggcagc gcgtgacagg ataccagcca tgagtgagtt tgcatggagc
    59641 tggaatgaac cacggccagc cattgatccg gccagattta cggagcacag gcaggaaact
    59701 gaaaccgacc tgcaacgcgc catccgttac taccttgagg cggacaaaaa ggcccgggaa
    59761 gaacaggaag cgaaggagga agcctttttc gcacaatccg ccatgggtaa aaaactcatg
    59821 gcatcccttg aggaagccgg acagcgtgaa aagctggcac agagcatcat cagtaagcgc
    59881 cgggcaacag aacaagaccc ggtggcccgt gcctttgcca cactgaaggc gcttcccgtt
    59941 tatctgcgag aacctctgag ccgccacctc tctttcctgc gcaagaagca ggaagccgat
    60001 cgtcagaaag gcaaaaagag ctggcaggcg gaacgctatg cacgcggaac cctgcgcaaa
    60061 atattcgaac gtctggaccg caccgacagc cgctggctga caccgggtta tcgctccctt
    60121 gccggacgcg aacgcctgga cgatttgctt tacctgccgc agctcaacaa acaccagata
    60181 cagacgctgg ccaccatgac ggcggcgatg ttcagcagca ccttcgaaaa actctgcgat
    60241 ggctttggcg cgactgatgg cgaactgacc atggatgtaa cgctgaaggc gtatcagatg
    60301 ctggcccgca tggcgttaca cctgcacgcc atgcctccac attatgacgc actgacaaca
    60361 gacaaagacc ggaggaacga accggacacg gagctgctgc cgggcgcaat ccttcgcctg
    60421 acctgtgcgg aatggtggaa acgcaaactg tggctgttac gttgcgagtg gagagaagaa
    60481 caactccgcg ccgcctgtct ggtttccaga aaaacatcac cctatctgag ccaggacgcg
    60541 ttaagcgagt ttcgcgcaca gcgcgagaaa acacgcgatt tcctgaaaag ttttatgctg
    60601 gaaaacgaag acgggttcac gattgatctc gaaacagtgt attacgcggg agtaagtaac
    60661 ccggttcacc gtaaggcaga aatgatggcc accatgaagg ggctggaact tctggccgaa
    60721 gcccgtggcg acaaagcggt gtttctgact gtcacctgcc cgtcaaaata ccacgccaca
    60781 acagagaacg gtcatccgaa tcccaaatgg aacggagcca ccatgcgcga ctccagcgat
    60841 tacctggtta acacgttttt tgcggcggtc cgcaagaaac tgaaccgcga cggcctgcgc
    60901 tggtatggca tccgcacggt ggagcctcac catgacggca ccgtgcactg gcatatgatg
    60961 gtctttgctc atccggaaga aatcgacacc attgtgtccc acacccgcga tattgccatt
    61021 caggaagatc gtcacgagct gggtgatgat attaccccac gctttaaggc ggagtacgtc
    61081 gacggctcaa aaggtacgcc aaccagctac atcgccacct acatcggaaa gaacctagac
    61141 agccgcgccg tggatggcat cgacccgaaa acgggcaagc cacgcgttga ccacgaaacc
    61201 ggaaaatcaa tggccgagag cgtggaacgc gccatcggct gggcgcgcct tcaccgtgtc
    61261 cgccagttcc agttctttgg tatcccctcc cgtcaggtgt ggcgtgaact ccgccgcctt
    61321 gccagccaga tggcacgcaa cccggaaggc ccgcaacggc tgaaggatga cgcaatggat
    61381 gcggtactcg ctgccgctga tgccggatgt tttgccacct acatagagaa acagggcggc
    61441 gtacttgttc cacgcaaaga ctacctgatt cgcaccgcct acgacctcgc agatgagctg
    61501 aacgattacg gcgaacagag tgtacagatt tacgggatct ggtcgccgct catcggggaa
    61561 tcctcccgtg tgtgcacgca tccggataac tggaagctgg taagacgtaa accggaagcg
    61621 gaagacagcg cccgcgaaaa tggttttgac cttcagggcg gccctgccgc cccttggact
    61681 cgtggcaata actgtccccg tgtacaggaa acggacaaca acgggacaga acagccggaa
    61741 gaacggccag caccgtggcc gcagcttcct gacggcgttg atgtggatga atgggtgcgc
    61801 tcactgaaac ggcacgaacg ccgggcgctg atgcgttcgc ttcgtgacaa acaggcaaaa
    61861 aacagcagtg atgaaatgca gagctggaca cagagccgca aacagcagcg gcctttgcct
    61921 gataaccacg aattactcgc tagagaatgg cgggagtctg ctgaatctct cggcctgcat
    61981 atcggtgaac aacaaatgca gcacctgtta cggggcggca gtctgtacgt tgacggcagc
    62041 atcattgcac cgcagggatt tgaaattgta cgcaaaccgg atacccgccc ggacagccga
    62101 atcacgcagc tctggcagcg cctgagccgt aatcacggtg taagcagcac ggagatccgc
    62161 cataacccgg tcgccagcta tctggcacag ctgggggcat cagaccctga agccgccaca
    62221 cgcctggcat ccacacttca gcaggaccag aacaccatga aaacacccgt taccgtgctt
    62281 tctgacatgc tgcgcgccat ccgcgacgca gagcacgcac agagaatcag tgaaaccact
    62341 gaacgtgccc gccgcaaagc agacctgctg cggggtggcc tgaccagtgg aaacaaaaaa
    62401 cagacagaaa cgggattcac aaatcccgta aatgagcaaa aaacgcgccg cgatatatga
    62461 agcgcacaca aaacaggcaa aaacgggatt tcagaatccc gtaaacgatt aattaatcaa
    62521 cataaggaaa agcgacatga aaatttgtat cgacgacggc tccaccaaca tcaagctggc
    62581 atggactgag aacagcgaac gccgcaacgc catcagcccg aacagcttca agtcggaatg
    62641 gtctgcgccg ttcggtggct cgcagcctgc gaactacatg cttgatggcg tgcgctatgg
    62701 ttttgatccg gtcagcgatc gctttgtcca gacgaccgac acgcaatacc agtacagcga
    62761 tgtgaatgta atcgccattc accacgcgct ggtcaaatca ggcatcacac cacaggaggt
    62821 ggatgtggtt gtcaccctgc cactgagcga gtatttcgac acaaacgcac agccggacat
    62881 ggccaacatc aaccgcaaaa aagcgaacgt tatgcgcccg gtggagtacc agaacggcga
    62941 agcattcact atccgtaacg tgcgggttat gcctgaatcc attccggctg gctttaaggc
    63001 actggctgac atgagtccgt ttgaatccct gctgattgtg gatttaggcg gaaccacgct
    63061 ggatgtggca aaggtccagg gacaactggc aggtatcagc caggtgtttt gcgatccaca
    63121 cgtaggcgtt tccctgatgg ccgatgccgt actgtcggtg atggccacta acggtatgcg
    63181 taccagtcac cacatcgcca ataccattat cgaacatcgc catgatgaag cctggttgcg
    63241 ccaacacatc cacaatgacg cgcattacgc cagcctgatg gcggttattc gtgaaaagga
    63301 agaaacactg aaacaacgcg tgatccgcgc gctggcgggt ttttcgggtt acggacgggt
    63361 gatggttgtc ggtggcgggg cggagattgt ggcacccgct atccgcgaag cctgcggagt
    63421 taatgcgact ttcatcgcgg acggggtgcc acagtttgct ctggttaatg ggctgtacgc
    63481 aatggacaag gagtaaacca atgacgacac caaccagacg
//
LOCUS       DAZUDJ010000020        62000 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.020, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000020 DAZUDJ010000000
VERSION     DAZUDJ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 62000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62000
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.020"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            322..408
                     /gene="leuL"
                     /locus_tag="ACHY1N_001815"
     CDS             322..408
                     /gene="leuL"
                     /locus_tag="ACHY1N_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HFS4044138.1"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
     gene            501..2072
                     /gene="leuA"
                     /locus_tag="ACHY1N_001816"
     CDS             501..2072
                     /gene="leuA"
                     /locus_tag="ACHY1N_001816"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HFS4044139.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     gene            2072..3163
                     /gene="leuB"
                     /locus_tag="ACHY1N_001817"
     CDS             2072..3163
                     /gene="leuB"
                     /locus_tag="ACHY1N_001817"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HFS4044140.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAACAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            3166..4566
                     /gene="leuC"
                     /locus_tag="ACHY1N_001818"
     CDS             3166..4566
                     /gene="leuC"
                     /locus_tag="ACHY1N_001818"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HFS4044141.1"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     gene            4577..5182
                     /gene="leuD"
                     /locus_tag="ACHY1N_001819"
     CDS             4577..5182
                     /gene="leuD"
                     /locus_tag="ACHY1N_001819"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HFS4044142.1"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN"
     gene            complement(5231..6409)
                     /gene="setA"
                     /locus_tag="ACHY1N_001820"
     CDS             complement(5231..6409)
                     /gene="setA"
                     /locus_tag="ACHY1N_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetA"
                     /protein_id="HFS4044143.1"
                     /translation="MIWIMTMARRMNGVYAAFMLVAFMMGVAGALQAPTLSLFLSREV
                     GAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRH
                     YLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPL
                     AFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVR
                     MLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVK
                     RYGKRRMMVIAVAAGVLFYTGLIFFHSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMP
                     GRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
                     "
     gene            complement(6511..6642)
                     /gene="sgrT"
                     /locus_tag="ACHY1N_001821"
     CDS             complement(6511..6642)
                     /gene="sgrT"
                     /locus_tag="ACHY1N_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0046325 - negative regulation of glucose
                     import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HFS4044144.1"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEELMQWDDRNSES"
     gene            6731..8386
                     /gene="sgrR"
                     /locus_tag="ACHY1N_001822"
     CDS             6731..8386
                     /gene="sgrR"
                     /locus_tag="ACHY1N_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706022.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SgrR"
                     /protein_id="HFS4044145.1"
                     /translation="MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     TTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
                     CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
                     IKSEKPAGLESLILTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIES
                     DIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     regulatory      8420..8519
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8550..9533
                     /gene="thiB"
                     /locus_tag="ACHY1N_001823"
     CDS             8550..9533
                     /gene="thiB"
                     /locus_tag="ACHY1N_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706021.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0030975 - thiamine binding [Evidence IEA];
                     GO_function: GO:0048502 - ABC-type thiamine transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HFS4044146.1"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPKIKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     ADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRT
                     STPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEQLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     gene            9509..11119
                     /gene="thiP"
                     /locus_tag="ACHY1N_001824"
     CDS             9509..11119
                     /gene="thiP"
                     /locus_tag="ACHY1N_001824"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HFS4044147.1"
                     /translation="MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGNWV
                     AVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALLQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKLPGRNVKTD"
     gene            11103..11801
                     /gene="thiQ"
                     /locus_tag="ACHY1N_001825"
     CDS             11103..11801
                     /gene="thiQ"
                     /locus_tag="ACHY1N_001825"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HFS4044148.1"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGSLTIDSVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAAQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTNELL
                     SGKASASALLGITG"
     gene            complement(11915..12679)
                     /gene="yabI"
                     /locus_tag="ACHY1N_001826"
     CDS             complement(11915..12679)
                     /gene="yabI"
                     /locus_tag="ACHY1N_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001148402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFS4044149.1"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWHAWVAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQNGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGG"
     gene            complement(12765..13643)
                     /gene="araC"
                     /locus_tag="ACHY1N_001827"
     CDS             complement(12765..13643)
                     /gene="araC"
                     /locus_tag="ACHY1N_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HFS4044150.1"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRA
                     YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCEEKVNDVAVKLS"
     gene            13982..15682
                     /gene="araB"
                     /locus_tag="ACHY1N_001828"
     CDS             13982..15682
                     /gene="araB"
                     /locus_tag="ACHY1N_001828"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008741 - ribulokinase activity [Evidence
                     IEA];
                     GO_process: GO:0019568 - arabinose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HFS4044151.1"
                     /translation="MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPLLNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKAQINASQKQLLPALTEAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPCSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
                     "
     gene            15693..17195
                     /gene="araA"
                     /locus_tag="ACHY1N_001829"
     CDS             15693..17195
                     /gene="araA"
                     /locus_tag="ACHY1N_001829"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFS4044152.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
     gene            17395..18090
                     /gene="araD"
                     /locus_tag="ACHY1N_001830"
     CDS             17395..18090
                     /gene="araD"
                     /locus_tag="ACHY1N_001830"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0019568 - arabinose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFS4044153.1"
                     /translation="MLEDLKRLVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPS
                     GVDYSVMTADDMVVVSIATGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     gene            18165..20516
                     /gene="polB"
                     /locus_tag="ACHY1N_001831"
     CDS             18165..20516
                     /gene="polB"
                     /locus_tag="ACHY1N_001831"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HFS4044154.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAF
                     IPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPLLLEKLNAWFANHDPD
                     VIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RVLVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     gene            20681..23587
                     /gene="rapA"
                     /locus_tag="ACHY1N_001832"
     CDS             20681..23587
                     /gene="rapA"
                     /locus_tag="ACHY1N_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0140658 - ATP-dependent chromatin
                     remodeler activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HFS4044155.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     gene            23599..24258
                     /gene="rluA"
                     /locus_tag="ACHY1N_001833"
     CDS             23599..24258
                     /gene="rluA"
                     /locus_tag="ACHY1N_001833"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HFS4044156.1"
                     /translation="MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     gene            complement(24375..25190)
                     /gene="djlA"
                     /locus_tag="ACHY1N_001834"
     CDS             complement(24375..25190)
                     /gene="djlA"
                     /locus_tag="ACHY1N_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HFS4044157.1"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     gene            25445..27799
                     /gene="lptD"
                     /locus_tag="ACHY1N_001835"
     CDS             25445..27799
                     /gene="lptD"
                     /locus_tag="ACHY1N_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA];
                     GO_process: GO:0043165 - Gram-negative-bacterium-type cell
                     outer membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HFS4044158.1"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     gene            27852..29138
                     /gene="surA"
                     /locus_tag="ACHY1N_001836"
     CDS             27852..29138
                     /gene="surA"
                     /locus_tag="ACHY1N_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0042277 - peptide binding [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0043165 - Gram-negative-bacterium-type cell
                     outer membrane assembly [Evidence IEA];
                     GO_process: GO:0050821 - protein stabilization [Evidence
                     IEA];
                     GO_process: GO:0060274 - maintenance of stationary phase
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HFS4044159.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     gene            29138..30127
                     /gene="pdxA"
                     /locus_tag="ACHY1N_001837"
     CDS             29138..30127
                     /gene="pdxA"
                     /locus_tag="ACHY1N_001837"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050570 - 4-hydroxythreonine-4-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HFS4044160.1"
                     /translation="MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLT
                     DRAAMLGLPLTLRPYSPNSPAQPQTTGTLTLLPVALRESVTAGQLAIENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ"
     gene            30124..30945
                     /gene="rsmA"
                     /locus_tag="ACHY1N_001838"
     CDS             30124..30945
                     /gene="rsmA"
                     /locus_tag="ACHY1N_001838"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFS4044161.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAE
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     gene            30948..31325
                     /gene="apaG"
                     /locus_tag="ACHY1N_001839"
     CDS             30948..31325
                     /gene="apaG"
                     /locus_tag="ACHY1N_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HFS4044162.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     gene            31332..32174
                     /gene="apaH"
                     /locus_tag="ACHY1N_001840"
     CDS             31332..32174
                     /gene="apaH"
                     /locus_tag="ACHY1N_001840"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008803 -
                     bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     ApaH"
                     /protein_id="HFS4044163.1"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGE
                     AAAS"
     gene            complement(32252..32731)
                     /gene="folA"
                     /locus_tag="ACHY1N_001841"
     CDS             complement(32252..32731)
                     /gene="folA"
                     /locus_tag="ACHY1N_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HFS4044164.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            complement(32923..34785)
                     /gene="kefC"
                     /locus_tag="ACHY1N_001842"
     CDS             complement(32923..34785)
                     /gene="kefC"
                     /locus_tag="ACHY1N_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015503 - glutathione-regulated potassium
                     exporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HFS4044165.1"
                     /translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGFIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
                     PLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     gene            complement(34778..35308)
                     /gene="kefF"
                     /locus_tag="ACHY1N_001843"
     CDS             complement(34778..35308)
                     /gene="kefF"
                     /locus_tag="ACHY1N_001843"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HFS4044166.1"
                     /translation="MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     gene            complement(35416..36747)
                     /gene="yaaU"
                     /locus_tag="ACHY1N_001844"
     CDS             complement(35416..36747)
                     /gene="yaaU"
                     /locus_tag="ACHY1N_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4044167.1"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     gene            complement(36806..37093)
                     /gene="fixX"
                     /locus_tag="ACHY1N_001845"
     CDS             complement(36806..37093)
                     /gene="fixX"
                     /locus_tag="ACHY1N_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HFS4044168.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     gene            complement(37090..38376)
                     /gene="fixC"
                     /locus_tag="ACHY1N_001846"
     CDS             complement(37090..38376)
                     /gene="fixC"
                     /locus_tag="ACHY1N_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4044169.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     gene            complement(38427..39368)
                     /gene="fixB"
                     /locus_tag="ACHY1N_001847"
     CDS             complement(38427..39368)
                     /gene="fixB"
                     /locus_tag="ACHY1N_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFS4044170.1"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGVQA
                     IQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     gene            complement(39383..40153)
                     /gene="fixA"
                     /locus_tag="ACHY1N_001848"
     CDS             complement(39383..40153)
                     /gene="fixA"
                     /locus_tag="ACHY1N_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HFS4044171.1"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     ALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
     gene            40627..42141
                     /gene="caiT"
                     /locus_tag="ACHY1N_001849"
     CDS             40627..42141
                     /gene="caiT"
                     /locus_tag="ACHY1N_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiporter"
                     /protein_id="HFS4044172.1"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
     gene            42172..43314
                     /gene="caiA"
                     /locus_tag="ACHY1N_001850"
     CDS             42172..43314
                     /gene="caiA"
                     /locus_tag="ACHY1N_001850"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA];
                     GO_process: GO:0009437 - carnitine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HFS4044173.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            43443..44660
                     /gene="caiB"
                     /locus_tag="ACHY1N_001851"
     CDS             43443..44660
                     /gene="caiB"
                     /locus_tag="ACHY1N_001851"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_process: GO:0009437 - carnitine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HFS4044174.1"
                     /translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     gene            44734..46287
                     /gene="caiC"
                     /locus_tag="ACHY1N_001852"
     CDS             44734..46287
                     /gene="caiC"
                     /locus_tag="ACHY1N_001852"
                     /EC_number="6.2.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016405 - CoA-ligase activity [Evidence
                     IEA];
                     GO_process: GO:0009437 - carnitine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="HFS4044175.1"
                     /translation="MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELN
                     QEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESA
                     WILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQ
                     PATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYL
                     TVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTL
                     MVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPG
                     DKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAK
                     VLEADGWLHTGDTGYCDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIV
                     VVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCS
                     GKIIRKNLK"
     gene            46396..47181
                     /gene="caiD"
                     /locus_tag="ACHY1N_001853"
     CDS             46396..47181
                     /gene="caiD"
                     /locus_tag="ACHY1N_001853"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HFS4044176.1"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGTEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMP
                     VEEAYRYIRSGVLKHYPSVLHSEDAVEGPLAFAEKRDPVWKGR"
     gene            47187..47777
                     /gene="caiE"
                     /locus_tag="ACHY1N_001854"
     CDS             47187..47777
                     /gene="caiE"
                     /locus_tag="ACHY1N_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HFS4044177.1"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR"
     gene            complement(47863..48258)
                     /gene="caiF"
                     /locus_tag="ACHY1N_001855"
     CDS             complement(47863..48258)
                     /gene="caiF"
                     /locus_tag="ACHY1N_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414576.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HFS4044178.1"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVAEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     gene            complement(48519..51740)
                     /gene="carB"
                     /locus_tag="ACHY1N_001856"
     CDS             complement(48519..51740)
                     /gene="carB"
                     /locus_tag="ACHY1N_001856"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFS4044179.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAA
                     DVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     ERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     gene            complement(51758..52906)
                     /gene="carA"
                     /locus_tag="ACHY1N_001857"
     CDS             complement(51758..52906)
                     /gene="carA"
                     /locus_tag="ACHY1N_001857"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HFS4044180.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK"
     gene            complement(53362..54183)
                     /gene="dapB"
                     /locus_tag="ACHY1N_001858"
     CDS             complement(53362..54183)
                     /gene="dapB"
                     /locus_tag="ACHY1N_001858"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFS4044181.1"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNSL"
     gene            complement(54350..55264)
                     /gene="rihC"
                     /locus_tag="ACHY1N_001859"
     CDS             complement(54350..55264)
                     /gene="rihC"
                     /locus_tag="ACHY1N_001859"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
                     /protein_id="HFS4044182.1"
                     /translation="MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNAEIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRKPLGIP
                     AFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVQVALDLDVKGFQQWVAEVLALAS"
     gene            complement(55330..56280)
                     /gene="ispH"
                     /locus_tag="ACHY1N_001860"
                     /gene_synonym="lytB"
     CDS             complement(55330..56280)
                     /gene="ispH"
                     /locus_tag="ACHY1N_001860"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA];
                     GO_process: GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HFS4044183.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
     gene            complement(56282..56731)
                     /gene="fkpB"
                     /locus_tag="ACHY1N_001861"
     CDS             complement(56282..56731)
                     /gene="fkpB"
                     /locus_tag="ACHY1N_001861"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFS4044184.1"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     gene            complement(56819..57313)
                     /gene="lspA"
                     /locus_tag="ACHY1N_001862"
     CDS             complement(56819..57313)
                     /gene="lspA"
                     /locus_tag="ACHY1N_001862"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFS4044185.1"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     gene            complement(57313..60129)
                     /gene="ileS"
                     /locus_tag="ACHY1N_001863"
     CDS             complement(57313..60129)
                     /gene="ileS"
                     /locus_tag="ACHY1N_001863"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFS4044186.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELSAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICGRCVSNVAGDGEKRKFA"
     gene            complement(60172..61113)
                     /gene="ribF"
                     /locus_tag="ACHY1N_001864"
     CDS             complement(60172..61113)
                     /gene="ribF"
                     /locus_tag="ACHY1N_001864"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HFS4044187.1"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     gene            complement(61121..61339)
                     /gene="yaaY"
                     /locus_tag="ACHY1N_001865"
     CDS             complement(61121..61339)
                     /gene="yaaY"
                     /locus_tag="ACHY1N_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 family protein"
                     /protein_id="HFS4044188.1"
                     /translation="MCRHSLRSDGAGFYQLAGCEYSFSAIKIAAGGHFLPVICAMAMK
                     SHFFLISVLNRRLTLTAVQGILGRFSLF"
     gene            61442..61705
                     /gene="rpsT"
                     /locus_tag="ACHY1N_001866"
     CDS             61442..61705
                     /gene="rpsT"
                     /locus_tag="ACHY1N_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFS4044189.1"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
BASE COUNT        14876 a        16930 c        16157 g        14037 t
ORIGIN      
        1 tcaccaaatc aatatcaaaa aaaatcgcaa aacatataat tcaatacaaa tcatcaggat
       61 aggttttgca acgcgtgcat tttgtcccct ttttcctcgt tgattagatg caaaaattta
      121 tgctgaaata tgtcaaccga tgaaaagcgt cggtagttaa gcagaaatta atatcgctta
      181 ctttaaccac cgcagcacaa ttagctaatt ttacgggtgc agaactcacg ctggcgggac
      241 gtttttattg cgtcagggtt gacatccgtt tttgtatcca gtaactctaa aagcatatcg
      301 cattcatctg gagctgattt aatgactcac atcgttcgct ttatcggtct actactacta
      361 aacgcatctt ctttgcgcgg tagacgagtg agcggcatcc agcattaagc cagcacgcag
      421 tcaaacaaaa aacccgcgcc attgcgcggg tttttttatg cccgaagcga ggcgctctaa
      481 aagagacaag gacccaaacc atgagccagc aagtcattat tttcgatacc acattgcgcg
      541 acggtgaaca ggcgttacag gcaagcttga gtgtgaaaga aaaactgcaa attgcgctgg
      601 cccttgagcg tatgggtgtt gacgtgatgg aagtcggttt ccccgtctct tcgccgggcg
      661 attttgaatc ggtgcaaacc atcgcccgcc aggttaaaaa cagccgcgta tgtgcgttag
      721 ctcgctgcgt ggaaaaagat atcgacgtgg cggccgaatc cctgaaagtc gccgaagcct
      781 tccgtattca tacctttatt gctacctccc caatgcacat cgccaccaag ctgcgcagca
      841 ccctggacga ggtgatcgaa cgcgctatct atatggtgaa acgcgcccgt aattacaccg
      901 atgatgttga attttcttgc gaagatgccg ggcgtacacc cattgccgat ctggcgcgag
      961 tggtcgaagc ggcgattaat gccggtgcca ccaccatcaa cattccggac accgtgggct
     1021 acaccatgcc gtttgagttc gccggaatca tcagcggcct gtatgaacgc gtacctaaca
     1081 tcgacaaagc cattatttcc gtacataccc acgacgattt aggcctggcg gtcggcaact
     1141 cactggcggc ggtacatgcc ggtgcacgcc aggtggaagg tgcaatgaac gggatcggcg
     1201 agcgtgccgg taactgttcg ctggaagaag tcatcatggc gattaaagtt cgtaaggata
     1261 ttctcaacgt ccacaccgcc attaatcacc aggaaatatg gcgcaccagc cagttagtta
     1321 gccagatttg taatatgccg atcccggcaa acaaagccat tgttggcagc ggcgcattcg
     1381 cacactcctc cggtatccac caggatggcg tgctgaaaaa ccgcgaaaac tacgaaatca
     1441 tgacaccaga atctattggt ctgaaccaaa tccagctgaa tctgacctct cgttcggggc
     1501 gtgcggcggt gaaacatcgc atggacgaga tggggtataa agaaagtgaa tataatttag
     1561 acaatttgta cgacgccttc ctgaagctgg cggacaaaaa aggtcaggtg tttgattacg
     1621 atctggaggc gctggccttc atcggtaagc agcaagaaga gccggagcat ttccgtctgg
     1681 attacttcag cgtgcagtct ggctctaacg atatcgccac cgccgccgtc aaactggcct
     1741 gtggcgaaga agtcaaagca gaagccgcca acggtaacgg tccggtcgat gccgtctatc
     1801 aggcaattaa ccgcatcact gactataacg tcgaactggt gaaatacagc ctgaccgcca
     1861 aaggtcacgg taaagatgcg ctgggtcagg tggatattgt cgccaactac aacggtcgcc
     1921 gcttccacgg cgtcggcctg gccaccgata ttgtcgagtc ctccgccaaa gccatggtgc
     1981 acgtactgaa caatatctgg cgtgccgcag aagtcgaaaa agagttgcaa cgcaaagctc
     2041 aacacaacga aaacaacaag gaaaccgtgt gatgtcgaag aattaccata ttgccgtatt
     2101 gccgggggac ggtattggtc cggaagtgat gacccaggcg ctgaaagtgc tggatgccgt
     2161 gcgcaaccgc tttgcgatgc gcatcaccac cagccattac gatgtaggcg gcgcagccat
     2221 tgataaccac gggcaaccac tgccgcctgc gacggttgaa ggttgtgagc aagccgatgc
     2281 cgtgctgttt ggctcggtag gcggtccgaa atgggaacat ttaccaccag accagcaacc
     2341 agaacgcggc gcgctgttgc ctttgcgtaa gcacttcaaa ttattcagca acctgcgccc
     2401 ggcaaaactg tatcaggggc tggaagcatt ctgtccgctg cgtgcagaca ttgccgctaa
     2461 cggcttcgac atcctgtgcg tgcgcgaact gaccggcggc atctatttcg gtcagccaaa
     2521 aggccgcgaa ggtagcggac aatatgaaaa agcgtttgat accgaggtgt atcaccgttt
     2581 tgagatcgag cgtattgccc gcatcgcgtt tgaatctgct cgtaaacgtc gccacaaagt
     2641 cacctcaatc gacaaagcta acgtgctgca atcctctatt ttatggcgtg aaatcgtcaa
     2701 cgagatcgcc acggaatacc cggatgtcga actggcgcat atgtacatcg acaacgccac
     2761 catgcagctg attaaagatc catcacagtt tgacgttctg ctgtgctcca acctgtttgg
     2821 cgacattctg tctgacgagt gcgcaatgat cactggctcg atggggatgt tgccttccgc
     2881 cagcctgaac gagcaaggtt ttggtctgta tgaaccggca ggcggctcag caccagatat
     2941 cgcaggcaaa aacatcgcca acccgattgc gcaaattctg tcgctggcac tgctgctgcg
     3001 ctacagcctg gatgccgatg atgcggcttg cgccattgaa cgcgccatta accgcgcatt
     3061 agaagaaggc attcgcaccg gggatttagc ccgtggcgct gccgccgtta gtaccgatga
     3121 aatgggcgat atcattgccc gctatgtggc agaaggggtg taatcatggc taaaacgtta
     3181 tacgaaaaat tattcgacgc tcacgtagtg tacgaagccg aaaacgaaac cccgctgtta
     3241 tatatcgacc gccacctggt gcatgaagtg acctcaccgc aggcgttcga tggtctgcgc
     3301 gcccacggtc gcccggtacg tcagccgggc aaaaccttcg ccactatgga tcacaacgtc
     3361 tctacccaga cgaaagacat taatgcctgt ggtgaaatgg cgcgcatcca gatgcaggag
     3421 ctgattaaaa actgcaaaga atttggcgtc gaactgtatg acctgaatca cccgtatcag
     3481 gggatcgtcc acgtaatggg gccggaacag ggcgtcacct tgccggggat gaccattgtc
     3541 tgcggcgact cgcataccgc cacccacggc gcgtttggcg cactggcctt tggtatcggc
     3601 acttccgaag ttgaacacgt actggcaacg caaaccctga aacagggccg cgcaaaaacc
     3661 atgaaaattg aagtccaggg caaagccgcg ccgggcatta ccgcaaaaga tatcgtgctg
     3721 gcaattatcg gtaaaaccgg tagcgcaggc ggcaccgggc atgtggtgga gttttgcggc
     3781 gaagcaatcc gtgatttaag catggaaggt cgtatgaccc tgtgcaatat ggcaatcgaa
     3841 atgggcgcaa aagccggtct ggttgcaccg gacgaaacca cctttaacta tgtcaaaggc
     3901 cgtttgcatg cgccgaaagg caaagatttc gacgacgccg ttgcctactg gaaaaccctg
     3961 caaaccgacg aaggcgcaac tttcgatacc gttgtcactc tgcaagcaga agaaatttca
     4021 ccgcaggtca cctggggcac caatccaggc caggtgattt ccgtgaacga caatattccc
     4081 gatccggctt cgtttgccga tccggttgaa cgcgcgtcgg cagaaaaagc gctggcctat
     4141 atggggctga aaccgggcat tccgctgacc gaagtggcta tcgacaaagt gtttatcggt
     4201 tcctgtacca actcgcgcat tgaagattta cgcgcggcag cggagatcgc caaagggcga
     4261 aaagtcgcgc caggcgtgca ggcactggtg gttcccggct ctggcccggt aaaagcccag
     4321 gcggaagcgg aaggtctgga taaaatcttt attgaagccg gttttgaatg gcgcttgcct
     4381 ggctgctcaa tgtgtctggc gatgaacaac gaccgtctga atccgggcga acgttgtgca
     4441 tccaccagca accgtaactt tgaaggccgc caggggcgcg gcgggcgcac gcatctggtc
     4501 agcccggcaa tggctgccgc tgctgctgtg accggacatt tcgccgacat tcgcaacatt
     4561 aaataaggag cacaccatgg cagagaaatt tatcaaacac acaggcctgg tggttccgct
     4621 ggatgccgcc aatgtcgata ccgatgcaat catcccgaaa cagtttttgc agaaagtgac
     4681 ccgtacgggt tttggcgcgc atctgtttaa cgactggcgt tttctcgatg aaaaaggcca
     4741 acagccaaac ccggacttcg tgctgaactt cccgcagtat cagggcgctt ccattttgct
     4801 ggcacgagaa aacttcggct gtggctcctc gcgtgagcac gcgccctggg cattgaccga
     4861 ctacggtttt aaagtggtga ttgcgccgag ttttgctgac atcttctacg gcaatagctt
     4921 taacaaccag ctgctgccgg tgaaattaag cgatgcagaa gtggacgaac tgtttgcgct
     4981 ggtgaaagcc aatccgggga tccatttcga cgtggatctg gaagcgcaag aggtgaaagc
     5041 gggagagaaa acctatcgct ttaccatcga tgccttccgc cgccactgca tgatgaacgg
     5101 tctggacagt attgggctta ccttgcagca cgacgacgcc attgccgctt atgaagcaaa
     5161 acaacctgcg tttatgaatt aatccccttg cccggtcaaa tgaccgggct ttccgctatc
     5221 gtccacgtca tcaaacgtct ttaacctttg cggttaaaaa taatgcgaca acagaaataa
     5281 ccgcaattac ccagtagaca gcaaagtgcc cccaactttg tgcaattgct ccctgaataa
     5341 cgccagccag aattaccccg gtagaaatac tgttagtaaa taaggtggta gctgcccccg
     5401 ctcttccagg cattaaatcc tgaaaccata gcatcccaat acccgcaaca atgccgataa
     5461 atacagcgtt aaaaagttgc agcgtcatca acgccatacg gctatgaaag aaaatcaatc
     5521 cggtgtaaaa cagtactcct gccgccactg ctatgaccat cattcgccgc ttaccataac
     5581 gtttgacata gtagccagcc agaatcattg ctggtatttc cagtccagct gccgtcccca
     5641 tcaggaaacc cgccagtttg tctggcaatc ctaactcgct actgatccac aacggcatat
     5701 caataatgta catggtgttg caggtccaca ttaacgtcga ggcgacaaat aacatccgta
     5761 cgttactatc ctgccagcca ccttgcattg ataaagcatt ttccgacggc agttctaccc
     5821 gcgccacaga cggaagcata aatgcaatca ataccagact gagtgtgaat atcccggcgg
     5881 caatcgaaaa catcaccgta aagccgtaat tcaacgccag cataaaggcc aacggtggac
     5941 cgataaccca tgccagagaa agctgcgcac gcatcaccga gctaaacatc accacttctc
     6001 gcgccgagtt atccgcatat tcccgcgcca gagcaaataa ctgtggcatt gccgtattgg
     6061 ccagagatgc cagaagcaca ccacaggtga taagcgtcag ataatgacga ttaaatgcaa
     6121 acaatagcgc attgccgata gccatcaaac agcaaaatat aatcagtttt cgccgatcgc
     6181 cctgactgtc agaacgtttt gccaaccaga ggcttacgcc gatcccagca atagcattca
     6241 ccgtataaaa gagtccgatc cagaaaggtt gcgcgccaac ctcacgactc agaaataagc
     6301 tcaatgtagg agcctgtagc gccccggcca cccccatcat aaaagcgacc agcataaatg
     6361 ccgcgtaaac accgttcata cggcgagcca tcgtcattat ccagatcata cgttcccttt
     6421 ttagcgcggc gagaataaaa aaaaccagca ggtataatct gctggcgggt gattttacac
     6481 caatactcag tcacacatga tgcaggcaag tcaactttca gaattgcggt catcccactg
     6541 catcagttct tcaagcatgg ttaatcgttg tgggacgctt aaccaacgca accagcacaa
     6601 cttcgctgtc gcggtaaaat agtgctgata aaactgacgc atggggcacc tccttgcttc
     6661 atcgttagga attattgact taatataggg aaaataaaat tgctgtcttt tgcgcaggag
     6721 ttcccctttt atgccatctg ctcgtctgca acaacagttc atccgcctgt ggcaatgctg
     6781 cgagggtaaa tcgcaggaca caacgctcaa cgaactggca gcgttattga gctgctcgcg
     6841 tcgtcatatg cgtaccctgc tcaacaccat gcaggatcgc ggctggctga cgtgggaagc
     6901 ggaagtcggg cgcggtaaac gctcgcgtct gacattcctc tataccgggc tggcgcttca
     6961 gcaacagcgg gcggaagacc tgctggagca ggatcgtatc gaccaactag tgcagttggt
     7021 tggcgacaaa gcgactgtgc ggcaaatgct ggtttctcat ctgggccgca gcttccgcca
     7081 ggggcggcac atcctgcgcg tgctctacta tcgtccgttg cgtaatctgc tacctggcag
     7141 cgcattgcgc cgttccgaaa cccatattgc ccggcaaatc ttcagttcgc taacgcgcat
     7201 aaatgaggaa aatggggaac tggaagcaga catcgcccac cactggcagc aaatatcacc
     7261 gcttcactgg cgtttctttt tgcgtccagg agtccatttt catcatggtc gtgaactgga
     7321 aatggacgac gtgatcgcct ctttaaaacg aatcaatacg ctgccgctct attcgcatat
     7381 tgcggacatt gtgtcgccga cgccctggac gctggatatc catctcacgc aaccggaccg
     7441 ctggttaccg ttactgctgg gacaagttcc ggcgatgatc ctgccgcgcg aatgggaaac
     7501 cctcagtaac tttgccagcc atcccatcgg caccggtccg tatgcggtga tccgcaacac
     7561 caccaatcaa ctgaaaattc aggcattcga tgacttcttc ggttaccggg cattaatcga
     7621 tgaagttaac gtctgggttc tgccggaaat tgccgacgag ccagctggag gtctgatgct
     7681 aaaaggtcca cagggtgagg aaaaagagat tgaaagccgc ctggaggaag gttgctacta
     7741 tttactgttc gacagccgca cccatcgcgg ggcgaatcag caagtcaggg actgggtaag
     7801 ctatgtgctt tctccaacta atctggtcta tttcgctgag gaacagtacc agcaactgtg
     7861 gttcccggct tatggactgc tcccccgttg gcaccatgcc cgcaccataa agagcgaaaa
     7921 accggctggc ctggaaagcc tcatcctgac cttttatcag gatcacagtg agcatcgggt
     7981 gattgccggg atcatgcagc agattctggc aagtcaccag gtcacgctgg aaatcaaaga
     8041 gatcagctac gatcagtggc atgaaggaga gatcgagagc gatatctggc ttaacagcgc
     8101 caactttacg ctgccgctgg atttttcgct gttcgcgcac ttgtgcgagg tgccgctgct
     8161 ccaacactgt attccgatcg actggcaagc cgacgccgcc cgctggcgca atggcgaaat
     8221 gaacctggcg aactggtgcc agcaactggt cgccagtaaa gcaatggtgc cgcttatcca
     8281 ccactggctg atcattcagg gacaacgcag tatgcgcggc ctgcgtatga ataccctcgg
     8341 ctggttcgat tttaaatcag cgtggtttgc gccgccggat ccatgattgc tggtagataa
     8401 caaaatcact acactaacgc cgttctcaac ggggtgccac gcaaacgcgt gcgctgagaa
     8461 aatacccgtc gaacctgatc cggataacgc cggcgaaggg atttgaggct ccttctcaag
     8521 tcctttgcca ctcttttttg aggtgcaaag tgttaaaaaa atgtcttccc ctgctgttgc
     8581 tgtgcacagc gcccgttttc gctaaacccg ttctgactgt ttatacctac gattccttcg
     8641 ccgccgactg ggggcctggt ccaaagatca aaaaagcttt tgaagccgac tgtaactgcg
     8701 aactgaaact ggtggcgctg gaagatggcg tttcgcttct caaccgtcta cggatggaag
     8761 gcaaaaatag taaagccgat gtggtgctgg ggctggataa caatctgtta gacgccgcca
     8821 gtaaaaccgg actatttgcc aaaagcggtg tggcagcgga tgccgttaac gttcccggcg
     8881 gctggaataa tgacactttc gtcccgtttg attacggcta tttcgccttc gtctatgaca
     8941 agaacaaact gaaaaacccg ccgcaaagcc tgaaagaatt ggttgagagc gatcagaact
     9001 ggcgggtgat ttatcaggat ccgcgcacca gtacgccggg gctgggcctg ctgttgtgga
     9061 tgcaaaaagt ctatggcgat gacgccccac aagcctggca aaaactggcg aagaaaaccg
     9121 tcacggtcac caaaggctgg agcgaagcct acggcctgtt tttaaaaggt gaaagcgatc
     9181 tggtactgag ttacaccacc tctccggctt atcacattct cgaagagaaa aaagataact
     9241 acgccgccgc gaactttagc gaaggtcact atctgcaggt ggaagtcgcc gcccgcaccg
     9301 ctgccagcaa gcagccggag ctggcgcaaa aattcctcca gtttatggtt tctccggctt
     9361 ttcagaatgc gatcccaacc ggtaactgga tgtatccggt ggcaaatgtc acgctgcctg
     9421 ccgggtttga acaattgacc aaaccggcca ccacgctgga gttcacacca gctgaagtgg
     9481 cggcacaacg tcaggcatgg attagcgaat ggcaacgcgc cgtcagccgt taattcccgg
     9541 ctggttaatt ccaggtgtaa gcgccgccac gctggtggta gcggttgcgc tcgcggcgtt
     9601 tctcgccctg tggtggaacg cgccgcaggg taactgggtg gcagtctggc aggacagcta
     9661 cctgtggcat gtggtgcgct tctccttctg gcaggcgttt ctctcggcgc tactctctgt
     9721 cgtacccgcg atattcctcg cccgcgccct ctatcgcagg cgctttccgg gtcggctggc
     9781 gctgttgcgt ctgtgcgcaa tgaccttgat cctcccggtg ctagttgctg ttttcggcat
     9841 tcttagcgtc tatggtcgtc agggctggct ggcatcgctc tgccaatcgc tcggtctgga
     9901 gtggaccttt tcgccctacg gcctgcaagg cattttgctg gcgcacgtat tttttaatct
     9961 gccgatggcg agccgcttat tactccaggc actggaaaac attcccggcg aacaacgtca
    10021 gcttgccgcc cagcttggga tgcgcggctg gcattttttc cgcttcgtcg aatggccgtg
    10081 gctacggcga caaatcccgc cggttgccgc gcttatcttt atgctctgtt tcgccagctt
    10141 cgccaccgtg ctatcgctgg gcggcggtcc gcaggcaact actatcgagc tggctattta
    10201 tcaggcgctg agttacgact acgatcctgc ccgcgcggcg atgctggcgc tgctccagat
    10261 ggtgtgttgc cttgggctgg tgctgttgag tcagcgacta agtaaggcca ttgcgcccgg
    10321 taccacgctg ctgcaaggct ggcgcgatcc ggacgatcgt ctgcatagcc gcatttgcga
    10381 cacggtgtta atagtgctgg cgctgctgct gttgctgcca ccgttgctgg cggtgatcgt
    10441 cgatggggta aatcgccagt tgccggaagt gctggcacaa ccggtgctgt ggcaggcgct
    10501 gtggacctcg ttgcgtattg cgctggcggc aggtgtattg tgcgtagtgc tgaccatgat
    10561 gctgctatgg agcagtcgcg aactgcgggc gcggcagaaa atgctggcgg gtcaggcgct
    10621 ggagatgagc ggcatgttga tcctcgccat gccggggatt gtgctggcta ccggcttctt
    10681 tttactgctc aacaacacta tcggcctgcc acaatctgct gacggcattg tgattttcac
    10741 caatgcgtta atggcgatcc cttatgcgct gaaagtactg gaaaacccga tgcgcgatat
    10801 caccgcccgc tacagtatgt tgtgtcagtc gctgggcatt gaaggctggt cgcgcttaaa
    10861 agtggtcgag ctgcgcgccc tgaaacgtcc actggcgcag gcgctggctt ttgcctgcgt
    10921 gctgtcgatt ggtgattttg gcgtagtggc gttgttcggt aacgatgatt tccgtaccct
    10981 gccgttttat ctctaccagc aaattggctc ctatcgcagc caggacggcg cggtcaccgc
    11041 gttaattctg ctactactct gttttctgct gtttaccgtg attgaaaaac taccggggcg
    11101 aaatgttaaa actgactgat atcacctggc tttatcacca tttgccgatg cgttttagct
    11161 taacggtaga acgcggcgag caggtggcaa tcctcgggcc aagcggcgcg ggtaaaagta
    11221 ccctgctgaa tttgattgcc ggttttctga cgccagccag cggttcgctg actatcgaca
    11281 gcgttgatca caccacgacg ccgccgtcac gccgtccggt atcgatgctg tttcaggaga
    11341 acaacctgtt cagccacctg acggtcgcgc agaacatcgg gctggggctt aatccgggat
    11401 tgaagctgaa cgcggcgcag caggagaaaa tgcacgctat cgcccgccag atggggattg
    11461 ataatttaat ggcgcggtta ccgggcgagc tttccggcgg tcagcgacag cgcgtggcgt
    11521 tagcgcgttg tctggtgcgc gaacagccga ttttattgct cgatgaaccg ttctctgcgc
    11581 tcgatccggc gttacgtcag gagatgctga cgctggtgag cacgagctgc cagcagcaaa
    11641 aaatgacgct attgatggtg tcgcacagtg tggaagatgc ggcgcggatc gccacacgct
    11701 cggtggtggt cgccgacggg cgcatcgcct ggcagggtaa gaccaatgag ttgttgagcg
    11761 gtaaggcgag tgcttcggca ctattgggga ttacgggtta gtatgcactg tcggatgcgg
    11821 cgtgaacgcc ttatccgacc tacgggtagt gcgttttgta ggcctgataa gacgcggtca
    11881 gcgtcgcatc aggcaacccg cacaagacta tctcctaacc cccaaccact ttacgcaaaa
    11941 tatcgatata caccggcatc aacgggtggc gaattaacac caccagcgcc accacgccga
    12001 tggcagaaat taacggcgtc agccacaaca aacggccgcg cgacaaataa tgacttaaac
    12061 gatcggttgc tttaccgctg cgccataacc gccagcacag ccagccacca acccacaaaa
    12121 ataccgccgt cgccagcagc aaccatttaa actcgccgtt ctgcattccg gctggaatat
    12181 cgatcgccgc gcccgccaga atcccaggca ggaagtaaaa cggtggccac agcaggcagc
    12241 cgataatatt cggcgtaatg aattttgcca ccggcagatc cagcattccc gccaccattg
    12301 gcaccagcgg acgcgtcggg ccaacaaagc gaccgaccag aatggtgaac atgctgtgtt
    12361 gatgcaacgc atgttcagtt ttatcgagta atgctttgtt tttcttcaga aatgaccagc
    12421 gatgcaacgg ctttttaaaa cgccagccca gccagaagga gatccagtcg cccagcagac
    12481 aaccgacaat ccctgccacc caggcgtgcc agaaacttaa ctcgccgctg ccaatcagcg
    12541 ctcccagccc cgccatcagc accgtaccgg gtagaatcaa accgaccagc gccagcgact
    12601 ccagaaaggc caccaacacc accgccatca atgaatacac ggtggattgg gtaataaagt
    12661 gttccagcaa tgcttgcata atgtgcctgt caaatggacg aagcagggat tctgcaaacc
    12721 ctatgctact ccgtcaagcc gtcaattgtc tgattcgtta ccaattatga caacttgacg
    12781 gctacatcat tcactttttc ttcacaaccg gcacggaact cgctcgggct ggccccggtg
    12841 cattttttaa atactcgcga gaaatagagt tgatcgtcaa aaccaacatt gcgaccgacg
    12901 gtggcgatag gcatccgggt agtgctcaaa agcagcttcg cctgactaat gcgttggtcc
    12961 tcgcgccagc ttaagacgct aatccctaac tgctggcgga aaagatgtga cagacgcgac
    13021 ggcgacaggc aaacatgctg tgcgacgctg gcgatatcaa aattgctgtc tgccaggtga
    13081 tcgctgatgt actgacaagc ctcgcgtaca cgattatcca tcggtggatg gagcgactcg
    13141 ttaatcgctt ccatgcgccg cagtaacaat tgctcaagca gatttatcgc cagcagctcc
    13201 gaatagcgcc cttccccttg cccggcgtta atgatttgcc caaacaggtc gctgaaatgc
    13261 ggctggtgcg cttcatccgg gcgaaagaaa cccgtattgg caaatattga cggccagtta
    13321 agccattcat gccagtaggc gcgcggacga aagtaaaccc actggtgata ccattcgcga
    13381 gcctccggat gacgaccgta gtgatgaatc tctcctggcg ggaacagcaa aatatcaccc
    13441 ggtcggcaga caaattctcg tccctgattt ttcaccaccc cctgaccgcg aatggtgaga
    13501 ttgagaatat aacctttcat tcccagcggt cggtcgataa aaaaatcgag ataaccgttg
    13561 gcctcaatcg gcgttaaacc cgccaccaga tgggcgttaa acgagtatcc cggcagcagg
    13621 ggatcatttt gcgcttcagc catacttttc atactcccgc cattcagaga agaaaccaat
    13681 tgtccatatt gcatcagaca ttgccgtcac tgcgtctttt actggctctt ctcgctaacc
    13741 caaccggtaa ccccgcttat taaaagcatt ctgtaacaaa gcgggaccaa agccatgaca
    13801 aaaacgcgta acaaaagtgt ctataatcac ggcagaaaag tccacattga ttatttgcac
    13861 ggcgtcacac tttgctatgc catagcattt ttatccataa gattagcgga tcctacctga
    13921 cgctttttat cgcaactctc tactgtttct ccatacccgt ttttttggat ggagtgaaac
    13981 gatggcgatt gcaattggcc tcgattttgg cagtgattct gtgcgagctt tggcggtgga
    14041 ctgcgccagc ggtgaagaga tcgccaccag cgtagagtgg tatccccgtt ggcaaaaagg
    14101 gcaattttgt gatgccccga ataaccagtt ccgtcatcat ccgcgtgact acattgagtc
    14161 aatggaagcg gcactgaaaa ccgtgcttgc agagcttagc gtcgaacagc gcgcagctgt
    14221 ggtcgggatt ggcgttgaca gtaccggctc gacgcccgca ccgattgatg ccgacggtaa
    14281 cgtgctggcg ctgcgcccgg agtttgccga aaacccgaac gcgatgttcg tattgtggaa
    14341 agaccacact gcggttgaag aagcggaaga gattacccgt ttgtgccacg cgccgggcaa
    14401 cgttgactac tcccgctata ttggcggtat ttattccagc gaatggttct gggcaaaaat
    14461 cctgcatgtg actcgccagg acagcgccgt ggcgcaatct gccgcatcgt ggattgagct
    14521 gtgcgactgg gtgccagctc tgctttccgg taccacccgc ccgcaggata ttcgtcgcgg
    14581 acgttgcagc gccgggcata aatctctgtg gcacgaaagc tggggcggcc tgccgccagc
    14641 cagtttcttt gatgagctgg acccgctcct caatcgccat ttgccttccc cgctgttcac
    14701 tgacacctgg actgccgata ttccggtggg caccttatgc ccggaatggg cgcagcgtct
    14761 cggcctgcct gaaagcgtgg tgatttccgg cggcgcgttt gactgccata tgggcgcagt
    14821 tggcgcaggc gcacagccta acgcactggt aaaagttatc ggtacttcca cctgcgacat
    14881 tctgattgcc gacaaacaga gcgttggcga gcgggcagtg aaaggtattt gcggtcaggt
    14941 tgatggcagc gtggtgcctg gatttatcgg tctggaagca ggccaatcgg cgtttggtga
    15001 tatctacgcc tggtttggtc gcgtactcgg ctggccgctg gaacagcttg ccgcccagca
    15061 tccggaactg aaagcgcaaa tcaacgccag ccagaaacaa ctgcttccgg cgctgaccga
    15121 agcatgggcc aaaaatccgt ctctggatca cctgccggtg gtgctcgact ggtttaacgg
    15181 ccgccgcaca ccgaacgcta accaacgcct gaaaggggtg attaccgatc ttaacctcgc
    15241 taccgacgct ccgctgctgt tcggcggttt gattgctgcc accgcctttg gcgcacgcgc
    15301 aatcatggag tgctttaccg atcaggggat cgccgtcaat aacgtgatgg cgctgggcgg
    15361 catcgcgcgg aaaaaccagg tcattatgca ggcctgctgc gacgtgctga atcgcccgct
    15421 gcaaattgtt gcctctgacc agtgctgtgc gctcggtgcg gcgatttttg ctgccgtcgc
    15481 cgcgaaagtg cacgcagaca tcccctcagc ccagcaaaaa atggccagtg cggtagagaa
    15541 aaccctgcaa ccgtgcagcg aacaggcaca acgctttgaa cagctttatc gccgctatca
    15601 gcaatgggcg atgagcgccg aacaacacta tcttccaact tccgccccgg cacaggctgc
    15661 ccaggccgtt ccgactctat aaggacacga taatgacgat ttttgataat tatgaagtgt
    15721 ggtttgtcat tggcagccag catctgtatg gcccggaaac cctgcgtcag gtcacccaac
    15781 atgccgagca cgtcgttaat gcgctgaata cggaagcgaa actgccctgc aaactggtgt
    15841 tgaaaccgct gggcaccacg ccggatgaaa tcaccgctat ttgccgcgac gcgaattacg
    15901 acgatcgttg cgctggtctg gtggtgtggc tgcacacctt ctccccggcc aaaatgtgga
    15961 tcaacggcct gaccatgctc aacaaaccgt tgctgcaatt ccacacccag tttaacgcgg
    16021 cgctgccgtg ggacagtatc gatatggact ttatgaacct gaaccagact gctcatggcg
    16081 gtcgcgagtt cggcttcatt ggcgcgcgta tgcgtcagca acatgccgtc gttaccggtc
    16141 actggcagga taaacaagcc catgagcgta tcggctcctg gatgcgtcag gcggtctcta
    16201 aacaggatac ccgtcatctg aaagtctgcc gatttggcga taacatgcgt gaagtggcgg
    16261 tcaccgatgg tgataaagtt gccgcacaga tcaagttcgg tttctccgtc aatacctggg
    16321 cggttggcga tctggtgcag gtggtgaact ccatcagcga cggcgatgtt aacgcgctgg
    16381 tcgatgagta cgaaagctgc tacaccatga cgcctgcaac acaaatccac ggcgaaaaac
    16441 gacagaacgt gctggaagcg gcgcgtattg agctggggat gaagcgtttc ctggaacaag
    16501 gtggcttcca cgcgttcacc accacctttg aagatttgca cggtctgaaa cagcttccag
    16561 gtctggccgt acagcgtctg atgcagcagg gttacggctt tgcgggcgaa ggcgactgga
    16621 aaactgccgc cctgcttcgc atcatgaagg tgatgtcaac cggtctgcag ggcggtacct
    16681 cctttatgga ggactacacc tatcacttcg agaaaggcaa tgacctggtg ctcggctccc
    16741 atatgctgga agtctgcccg tcgattgcag tagaagagaa accgatcctc gacgttcagc
    16801 atctcggtat tggtggtaag gacgatcctg cccgcctgat cttcaatacc caaaccggtc
    16861 cagcgattgt tgccagcctg attgatctcg gcgatcgtta ccgtctgctg gttaactgta
    16921 tcgacacggt gaaaaccccg cactccctgc cgaaactgcc ggtggcgaat gcgctgtgga
    16981 aagcgcaacc ggatctgcca actgcttccg aagcgtggat cctcgctggt ggcgcgcacc
    17041 ataccgtctt cagccatgcg ctgaacctca acgatatgcg ccagttcgcc gagatgcacg
    17101 acattgaaat cacggtgatt gataacgaca cccgcctgcc agcgtttaaa gacgcactgc
    17161 gctggaacga agtgtattac ggatttcgtc gctaagtagc cacatcaggt atgtaacgcc
    17221 tgatgcgacg ctgacgcgtc ttatctggcc tacgcgctgt gtttttgtag gccggataag
    17281 caaagcgcat ccggcattca acgcctgatg cgacgctggc gcgtcttatc aggcctacgc
    17341 gctgcgattt tgtagaccgg ataagcaaag tgcatccggc acgaaggagt caacatgtta
    17401 gaagatctca aacgcctggt attagaagcc aacctggcgc tgccaaaaca caacctggtc
    17461 acgctcacat ggggcaacgt cagcgccgtt gatcgcgagc gcggcgtctt tgtgatcaaa
    17521 ccttccggcg tcgattacag cgtcatgacc gctgacgata tggtcgtggt tagcatcgca
    17581 accggtgaag tggttgaagg tacgaaaaag ccctcctctg acacgccaac tcaccggctg
    17641 ctctatcagg cattcccgtc cattggcggc attgtgcata cgcactcgcg ccacgccacc
    17701 atctgggcgc aggcgggtca gtcgattcca gcaaccggca ccacccacgc cgactatttc
    17761 tacggcacca ttccctgcac ccgcaaaatg accgacgcag aaatcaacgg tgaatatgag
    17821 tgggaaaccg gtaacgtcat cgtagaaacc ttcgaaaaac agggtatcga tgcagcgcaa
    17881 atgcccggcg tcctggtcca ttctcacggc ccatttgcat ggggcaaaaa tgccgaagat
    17941 gcggtgcata acgccatcgt gctggaagag gtcgcttata tggggatatt ctgccgtcag
    18001 ttagcgccgc agttaccgga tatgcagcaa acgctgctgg ataaacacta tctgcgtaag
    18061 catggcgcga aggcatatta cgggcagtaa tgactgtata aaaccacagc caatcaaacg
    18121 aaaccaggct ataatcaagc ctggtttttt attggatttt caacgtggcg caggcaggtt
    18181 ttatcttaac ccgacactgg cgggataccc cgcaagggac agaagtctcc ttctggctgg
    18241 cgacggacaa cgggccgttg caggttacgc ttgcaccgca agagtccgtg gcgtttattc
    18301 ctgccgatca ggttccccgc gctcagcata ttttgcaggg tgaacaaggc tttcgcctga
    18361 caccgctggc gttaaaggat tttcaccgcc agccggtgta tggcctttac tgtcgcgccc
    18421 atcgccaatt gatgaattac gaaaagcgcc tgcgtgaagg tggcgttacc gtctacgagg
    18481 ccgatgtgcg cccgccagaa cgctatctga tggagcggtt tatcacctca ccggtgtggg
    18541 tcgagggtga tatgcacaat ggcactatcg ttaatgcccg tctgaaaccg catcccgact
    18601 atcgtccgcc gctcaagtgg gtttctatag atattgaaac cacccgccac ggtgagctgt
    18661 actgcatcgg cctggaaggc tgcgggcagc gcatcgttta tatgctgggg ccggagaatg
    18721 gcgacgcctc ctcgcttgat ttcgaactgg aatacgtcgc cagccgcccg ctgctgctgg
    18781 aaaaactcaa cgcctggttt gcaaaccacg atcccgatgt gatcatcggc tggaacgtgg
    18841 tgcagttcga tctgcgaatg ctgcaaaaac atgccgagcg ttaccgtctt ccgctgcgtc
    18901 ttgggcgcga taatagcgag ctggagtggc gcgagcacgg ctttaaaaac ggcgtctttt
    18961 ttgcccaggc taaaggtcgg ctaattatcg acggtatcga ggcgctgaaa tccgcgttct
    19021 ggaatttctc ttcattctcg ctggaaactg tcgctcagga gctattaggc gaaggaaaat
    19081 ctatcgataa cccgtgggat cgaatggacg aaattgaccg ccgtttcgcc gaagataaac
    19141 ctgcgctggc aacttataac ctgaaagatt gcgagctggt gacgcagatc ttccacaaaa
    19201 ctgaaatcat gccattttta ctcgaacgag caacggtgaa cggcctgccg gtggatcggc
    19261 acggcggttc ggtggcagcg tttggtcatc tctattttcc gcgaatgcat cgcgctggtt
    19321 atgtcgcgcc taatctcggc gaagtgccac cgcacgccag ccctggcggc tacgtgatgg
    19381 attcacggcc agggctttat gattcagtgc tggtgctgga ctataaaagc ctgtacccgt
    19441 cgatcatccg cacctttctg attgatcccg tcgggctggt tgaaggcatg gcgcagcctg
    19501 atccagagca cagtaccgaa ggttttctcg atgcctggtt ctcacgggag aaacattgcc
    19561 tgccggagat tgtgactaac atctggcacg ggcgcgatga agccaaacgt cagggtaata
    19621 aaccactttc gcaggcgctg aagatcatta tgaatgcctt ttatggcgtg cttggcacca
    19681 ccgcctgccg ctttttcgat ccgcgcctgg catcgtcgat caccatgcgt ggtcatcaga
    19741 tcatgcggca aaccaaagca ttgattgaag cgcagggcta cgacgttatc tacggagata
    19801 ccgactcgac ttttgtctgg ctaaaaggtg cacattcgga agaagaggcg gcgaaaatcg
    19861 gtcgtgtact ggtgcagcac gttaacgcct ggtgggcgga aacgctgcaa aaacaacggc
    19921 tgaccagcgc attagaactg gagtatgaaa ctcatttctg ccgttttctg atgccaacca
    19981 ttcgcggagc cgataccggc agtaaaaagc gctacgccgg gctgattcag gagggcgata
    20041 aacagcggat ggtgtttaaa gggctggaaa ccgtgcgcac cgactggacg ccgctggccc
    20101 agcagtttca gcaggagcta tacctgcgca tcttccgcaa cgagccatat caggaatatg
    20161 tacgcgaaac catcgacaaa ctgatggcgg gtgaactgga tgcgcgactg gtttaccgta
    20221 aacgccttcg ccgtccgctg agcgagtatc agcgtaatgt gccgcctcat gtacgcgccg
    20281 ctcgccttgc cgatgaagaa aaccaaaagc gcggtcgccc cttgcaatat cagaatcgcg
    20341 gcaccattaa gtacgtatgg accaccaacg gcccggagcc gctggactac caacgttcac
    20401 cactggatta cgaacactat ctgacccgcc agctacaacc cgtggcggag ggaatactcc
    20461 cttttattga ggataatttt gctacactta tgaccgggca acttgggcta ttttgagcaa
    20521 aaaaaagagt tcgccagata ccattttgat gcgtgacgaa tgctttgcca tccagtacca
    20581 tagcgccctt tccattcctg gacctgaata acaccactac ctcataagca cggtagcggg
    20641 tggttattgc ctgcaattaa agatatagag ccgaacacat atgcctttta cacttggtca
    20701 acgctggatc agcgatacag aaagcgaatt gggacttgga accgttgtcg cggtggatgc
    20761 gcgaactgtc actttacttt tcccatctac tggtgaaaac cgtctgtacg cacgcagtga
    20821 ttcccccgtg acccgcgtga tgttcaaccc tggtgatact attaccagcc atgacggctg
    20881 gcagatgcaa gtcgaagaag taaaagaaga aaatggcttg ctgacctata tcggtactcg
    20941 cctggatact gaagagtccg gcgtagccct gcgtgaagtt ttccttgata gcaaactggt
    21001 gttcagcaaa ccgcaggacc gtctgtttgc cgggcagatt gaccgtatgg accgctttgc
    21061 gctgcgttat cgcgcgcgta agtattccag cgaacagttc cgtatgccgt acagcggcct
    21121 gcgcggtcag cgtaccagcc tgattccgca tcagctcaac atcgctcatg atgttggtcg
    21181 ccgccacgcg ccgcgcgtcc tgctggctga cgaagtgggt ttagggaaaa ccattgaagc
    21241 cgggatgatc ctgcatcagc aactgctctc tggcgctgct gaacgtgtgc tgattatcgt
    21301 cccggaaacc ttacagcatc agtggctggt agaaatgctg cgccgtttca acctgcgctt
    21361 tgcactgttt gatgatgagc gttatgccga agctcagcac gatgcttaca acccgtttga
    21421 caccgaacag ctggtgattt gctcgctgga ttttgcccgt cgtagcaaac agcgcctgga
    21481 acatctctgt gaagccgaat gggacctgct ggtggtcgat gaagcgcatc acctggtgtg
    21541 gagcgaagat gcgccaagcc gtgaatatca ggccattgaa caactggcag agcacgtgcc
    21601 gggcgttctg ctgctgaccg cgaccccgga acagctgggg atggaaagcc acttcgcccg
    21661 tctgcgtctg ctggacccga accgtttcca cgattttgcg cagttcgttg aagagcagaa
    21721 aaattatcgt ccggttgcgg acgccgttgc catgctgctg gcaggtaaca aactgagcaa
    21781 tgacgaactg aacatgctcg gcgagatgat cggcgagcag gatatcgagc cgctgttgca
    21841 ggcagcaaac agcgacagcg aagatgccca gagcgcccgt caggagctgg tttcgatgct
    21901 gatggatcgc cacggcacca gccgcgtgct gttccgtaac acgcgtaacg gtgtgaaagg
    21961 attcccgaaa cgcgagctgc acaccattaa actgccgcta ccgacgcagt atcagacggc
    22021 tattaaagtc tccggcatta tgggcgcacg taaaagtgcg gaagatcgtg ctcgcgatat
    22081 gctctacccg gagcgtattt atcaggaatt tgaaggtgat aacgccacct ggtggaactt
    22141 cgatccgcgc gttgagtggc tgatgggcta cctgaccagc catcgctctc agaaagtgct
    22201 ggtgatctgc gccaaagctg ccactgcgct gcaactggag caggtactgc gcgaacgtga
    22261 aggtattcgc gctgcggtgt tccacgaagg tatgtcgatt atcgaacgtg accgcgctgc
    22321 cgcctggttt gccgaagaag acaccggcgc acaggtactg ctgtgctcag aaatcggttc
    22381 tgaaggacgt aacttccagt tcgccagcca catggtgatg tttgacctgc cattcaaccc
    22441 ggatctactg gagcagcgta ttggtcgtct ggatcgtatc ggccaggcgc acgatattca
    22501 gatccatgtg ccttatctgg agaaaaccgc tcagtcggtg ctggtgcgct ggtatcacga
    22561 aggtctggat gcatttgagc acacctgccc gaccggacgc actatttacg atagcgtata
    22621 caacgatctg attaactatc tggcttcacc ggatcaaacc gaaggctttg acgatctgat
    22681 caaaaactgc cgcgagcaac atgaagcgct gaaagcacag ctggaacagg gtcgtgaccg
    22741 cctgctggaa atccactcca acggtggcga aaaagcccag gcactggcag aaagcattga
    22801 agagcaggat gacgatacca acctgatcgc cttcgccatg aacctgttcg atattatcgg
    22861 tatcaatcag gacgatcgcg gcgacaacat gatcgtgctg acgccgtccg atcatatgct
    22921 ggtgccggac ttccctggcc tgtcggaaga tggcatcacc atcacctttg atcgtgaagt
    22981 ggcactggcg cgtgaagatg cacagtttat tacctgggag catccgctga tccgcaacgg
    23041 tctggatctg atcctttctg gcgataccgg tagcagcacg atttcactgt taaaaaacaa
    23101 agcgttgccg gtaggtacgc tgttggtgga actgatttat gtggttgaag cccaggctcc
    23161 gaagcagttg cagctcaacc gcttcctgcc accgacgccg gtacgtatgc tgctggataa
    23221 aaacggcaac aacctggcgg cgcaggtaga gtttgaaacc tttaaccgcc agcttaacgc
    23281 ggttaaccgt cacaccggca gcaaactggt taacgccgtg cagcaggatg ttcacgctat
    23341 ccttcaactg ggtgaagcgc agatcgagaa atctgcccgt gcattgattg atgcagcgcg
    23401 taacgaagcc gacgaaaaac tgtctgccga gctgtctcgt ctggaagctc tgcgtgcagt
    23461 gaacccgaac attcgtgacg acgaactgac cgccattgag agcaaccgtc agcaggtaat
    23521 ggaaagcctg gatcaggcag gctggcgtct ggatgccctg cgtttgatcg ttgtaacgca
    23581 tcagtaacgg agccgaaaat ggggatggaa aactacaatc caccgcagga accctggttg
    23641 gttatcctgt atcaggatga ccacattatg gtggttaaca agccgagcgg tttgttgtct
    23701 gtgccgggtc gtctggaaga gcacaaagat agcgtgatga cgcgcattca gcgtgattat
    23761 ccgcaggcag aatcggtgca tcgtctggat atggctacca gcggcgtgat tgtagtggcg
    23821 ctgaccaaag ccgcggagcg ggagttaaaa cgccagttcc gcgagcgcga gccgaaaaag
    23881 cagtatgtgg cccgcgtctg ggggcatcca tcccccgcag aaggtctggt ggatctgccg
    23941 ctgatttgcg actggccaaa ccgcccgaaa cagaaagtct gttacgaaac gggtaaacct
    24001 gcgcagacgg aatatgaagt ggtggagtat gcggcggata acacggcaag agtggtgtta
    24061 aaaccgatta ccgggcgttc gcatcaattg cgtgtgcata tgctggcgct gggtcatccg
    24121 attctcggcg atcgttttta tgcatcacca gaagcgagag cgatggcacc acgtttgttg
    24181 ctacatgcag agatgttgac gattacccat ccggcgtatg gcaatagtat gacgtttaaa
    24241 gcgccagcgg atttttaatc gtcacgctgg cgcagttcgg taggcggata aggcgttcac
    24301 gccgcatccg gcaattgtgc gccgattgcc tgatgcgacg cgggccgcgt cttatcaggc
    24361 ctacagttta aaacttattt aaaccctttc tgctgcttta tcagctcata tgcctgctga
    24421 atttcctgcg ctttctgctt cgccatctcc atcatctcag gcggcaaacc tttcgccacc
    24481 agcttatcgg gatggtgttc actcatcagc ttacggtagg cacgtttgat ggtggtcgca
    24541 tcatccgtcg gcttcacgcc cagcacatta caggcatctt ccagcgtcgg gccacgctgc
    24601 gcttgctgcc agttaccacc gccagattgc tgctgataac cgccgccaaa ctgtgcaccg
    24661 ccctgcatca tgcgcaaaaa ctggtcaaac tgggcgcggg agatccctaa ttcttcagca
    24721 atgacataca gcaccgcccg ttcattcggg tgcagtgaac catcagcaaa cgccgcctga
    24781 atctggatct ccaaaaacat acgaattaag tcaaaacgac caaagcagac actgcgaaac
    24841 tggcgcatct tttcgcgcag cgggtaatta tctgattttc ccactcggaa cgcgttttgc
    24901 gccgcagtac gggaagcgcc atgaaggttc attcggtcca tcaactggct ggcgatatga
    24961 atatcagcct ccgtgacgcg acctttggat ttggttaaat gccccatcac ttcaaaagtg
    25021 gtggcaaaaa acagcgcctg acgctcacgc tggttggcga accacgccat tttacggcta
    25081 cgggctttat caaacatatg gccaattaac aggcctaaca ctacgcccca aaagccgccg
    25141 cccatcagta aggccacggc cacgccaatg atttttcccc aatactgcat atattcccca
    25201 aatcgacaca cggatatcag ggctatctcc cacaatataa aggtgctttt accgttttcc
    25261 ggctgcggtc aattgtggga catcgcctat aatttgcatt atcatacctg tcattcaatg
    25321 ccgtgcctaa caccactgac gctattcgga caggattaac actagcgtag agatgacgag
    25381 tacgttagtc tctgaccgtt tgtcacgcgc aacgttaccg atgatggaac aataaaatca
    25441 acgtatgaaa aaacgtatcc ccactctcct ggccaccatg attgccaccg ccctttatag
    25501 tcaacaggga ctggcagccg acctcgcctc acagtgcatg ttgggcgtgc caagctatga
    25561 ccgtcctctg gtacagggcg ataccaatga cttacccgtg actatcaatg ctgaccacgc
    25621 gaaaggggac tacccggatg acgccgtgtt tactggcagc gtggatatca tgcagggtaa
    25681 cagccgtctg caggccgacg aagtgcagct ccatcaaaaa gaggcaccag gacaaccgga
    25741 gccggtacgt accgttgatg cgctcggtaa tgtccattac gacgataacc aggtgatcct
    25801 caaagggccg aaaggctggg cgaatctgaa caccaaagat accaacgtct gggaaggtga
    25861 ttaccagatg gtgggtcgcc agggtcgcgg taaagcggac ctgatgaaac aacgtggcga
    25921 aaaccgctat accattctgg ataacggtag ctttacctcc tgtctgccgg gttctgacac
    25981 ctggagcgtg gtaggtagcg aaattattca tgaccgcgaa gaacaagttg cggagatctg
    26041 gaacgcccgc tttaaggtgg gtccggtacc gatcttttat agcccctatt tgcagttgcc
    26101 ggtgggtgac aaacgtcgct ctggtttctt gatcccgaac gccaagtaca ccaccaccaa
    26161 ctactttgag ttctacctgc catattactg gaacatcgcg ccaaatatgg atgccaccat
    26221 cacgccgcat tatatgcatc gtcgtggcaa catcatgtgg gagaacgaat tccgctacct
    26281 ctcccaggcg ggcgctggct tgatggaact ggactatctg ccttcagata aagtctatga
    26341 agatgaacac ccgaacgatg acagttcacg tcgttggtta ttctactgga accactccgg
    26401 ggtcatggat caggtgtggc gtttcaacgt cgactacacc aaggtcagcg atcctagcta
    26461 cttcaatgat ttcgataaca agtacggttc cagtactgac ggctacgcaa cgcaaaaatt
    26521 cagcgttggc tatgcggtgc aaaacttcaa tgccaccgtt tcaaccaagc agttccaggt
    26581 tttcagcgaa cagaacacca gtagctactc ggcagagccg cagttagacg ttaattacta
    26641 ccagaatgat gttggtccgt ttgatacgcg tatttacggc caggcagtgc actttgttaa
    26701 caccagagac gacatgcctg aagcaacccg tgttcacctg gaaccgacca tcaatttgcc
    26761 gctctctaat aactggggca gcatcaatac cgaagcgaag ttgctggcaa cccattatca
    26821 gcaaaccaat cttgactggt ataactccag aaacacgacc aagctggacg aatccgttaa
    26881 ccgcgtaatg ccgcaattca aagttgacgg caaaatggtc tttgaacgcg atatggaaat
    26941 gctggctccg ggttataccc aaacgctgga accgcgcgcg cagtatttgt acgtgccgta
    27001 tcgcgatcag agcgacatct ataactacga ctcgtctctg ctgcaatctg actactctgg
    27061 cctgttccgg gaccggactt acggcggtct tgaccgtatt gcctccgcta accaggtgac
    27121 gaccggtgtc acatctcgca tatatgatga tgctgccgtt gaacgtttta atatttccgt
    27181 tggtcaaatc tactatttca cggagtctcg cactggcgat gacaacataa catgggagaa
    27241 tgacgacaaa acgggttcac tggtgtgggc aggcgatact tactggcgta tctccgagcg
    27301 ttggggattg cgtggcggga ttcagtacga tacacgtctg gataacgtag cgaccagtaa
    27361 ctccagcatt gaataccgtc gggatgaaga ccgtctggta cagctgaatt accgttacgc
    27421 cagcccggaa tatattcagg ctacgctgcc taagtactat tccactgctg agcaatataa
    27481 gaatggtatt tcgcaggtag gtgctgtcgc cagctggcca attgccgatc gttggtccat
    27541 tgttggggcc tactactacg acaccaatgc gaacaagcaa gccgactcta tgttaggtgt
    27601 gcaatacagc tcctgctgct atgcaattcg cgtcggttac gagcggaagc tgaacggttg
    27661 ggataacgat aaacaacatg cggtatatga caacgcaatc ggctttaaca tcgaacttcg
    27721 cggcctgagc tccaactacg gtctgggtac gcaagagatg ctgcgttcga acattctgcc
    27781 gtatcaaaac actttgtgat ttgttgattt accacgtaat ccgcagtgcg gttaattgaa
    27841 atggaaaaag tatgaagaac tggaaaacgc tgcttctcgg tatcgccatg atcgcgaata
    27901 ccagtttcgc tgccccccag gtagtcgata aagtcgcagc cgtcgtcaat aacggcgtcg
    27961 tgctggaaag cgacgttgat ggattaatgc agtcggtaaa actgaacgct gctcaggcaa
    28021 ggcagcaact tcctgatgac gcgacgctgc gccaccaaat catggaacgt ttgatcatgg
    28081 atcaaatcat cctgcagatg gggcagaaaa tgggagtgaa aatctccgat gagcagctgg
    28141 atcaggcgat tgctaacatc gcgaaacaga acaacatgac gctggatcag atgcgcagcc
    28201 gtctggctta cgatggactg aactacaaca cctatcgtaa ccagatccgc aaagagatga
    28261 ttatctctga agtgcgtaac aacgaggtgc gtcgtcgcat caccatcctg ccgcaggaag
    28321 tcgaatccct ggcgcagcag gtgggtaacc aaaacgacgc cagcactgag ctgaacctga
    28381 gccacatcct gatcccgctg ccggaaaacc cgacctctga tcaggtgaac gaagcggaaa
    28441 gccaggcgcg cgccattgtc gatcaggcgc gtaacggcgc tgatttcggt aagctggcga
    28501 ttgctcattc tgccgaccag caggcgctga acggcggcca gatgggctgg ggccgtattc
    28561 aggagttgcc cgggatcttc gcccaggcat taagcaccgc gaagaaaggc gacattgttg
    28621 gcccgattcg ttccggcgtt ggcttccata ttcttaaagt taacgacctg cgcggcgaaa
    28681 gcaaaaatat ctcggtgacc gaagttcatg ctcgccatat tctgctgaaa ccgtcgccga
    28741 tcatgactga cgaacaggcc cgtgtgaaac tggaacagat tgctgctgat atcaagagtg
    28801 gtaaaacgac ttttgctgcc gcagcgaaag agttctctca ggatccaggc tctgctaacc
    28861 agggcggtga tctcggctgg gctacaccag atattttcga tccggccttc cgtgacgccc
    28921 tgactcgcct gaacaaaggt caaatgagtg caccggttca ctcttcattc ggctggcatt
    28981 taatcgaact gctggatacc cgtaatgtcg ataaaaccga cgctgcgcag aaagatcgtg
    29041 cataccgcat gctgatgaac cgtaagttct cggaagaagc agcaagctgg atgcaggaac
    29101 aacgtgccag cgcctacgtt aaaatcctga gcaactaatg gttaaaaccc aacgtgttgt
    29161 gatcactccc ggcgagcccg ccgggattgg cccggactta gttgtccagc ttgcacagcg
    29221 tgagtggccg gtcgaactgg ttgtttgtgc cgatgccact ctccttaccg accgggcagc
    29281 gatgctcggt ttgccgctca ccctccgccc ttattccccc aactcccctg cacaaccgca
    29341 aactacgggc acattaacgc tacttcctgt cgcgctacgt gaatctgtca ctgcggggca
    29401 gttagcgatt gaaaatggac attacgtggt ggagacgctg gcgcgagcgt gtgatggctg
    29461 tctgaacggt gaatttgctg cgctgatcac aggccccgtg cataaaggcg tcattaacga
    29521 cgcaggcatt ccgtttaccg gtcataccga gtttttcgaa gagcgttcgc aggcgaaaaa
    29581 agtggtgatg atgctggcga ccgaagaact tcgcgtggcg ctggcaacga cgcatttacc
    29641 gctgcgcgat atcgcagatg ctatcacccc tgcacttttg cacgaagtga ttgctatttt
    29701 gcatcacgat ttgcgtacaa aatttggtat tgccgaaccg cgcattctgg tctgcgggct
    29761 gaatccgcac gcgggcgaag gcggtcatat gggtacggaa gagatagaca ccattattcc
    29821 ggtgctcgac gagctgcggg cgcagggaat gaaactcaac gggccgctgc ctgccgatac
    29881 cctgtttcag ccgaaatatc tcgataacgc cgacgccgtg ctggcgatgt accacgatca
    29941 gggtcttccc gtgctaaaat accagggctt cgggcgcggt gtgaacatta cgctgggcct
    30001 gccctttatt cgcacatcag tggaccacgg caccgcgctt gaactggcgg gacgtggcga
    30061 agccgatgtc ggcagtttta ttacggcgct taatctcgcc atcaaaatga ttgttaacac
    30121 ccaatgaata atcgagtcca ccagggccac ttagcccgta aacgcttcgg gcaaaacttt
    30181 ctcaacgatc agttcgtgat cgacagcatt gtttctgcca ttaacccgca aaagggccag
    30241 gcaatggtcg aaatcggccc cggtctggcg gcattgaccg agccggtcgg cgaacgtctg
    30301 gaccagctga cggtcatcga acttgaccgc gatctggcgg cacgtctgca aacgcatcca
    30361 ttcttaggcc cgaaactgac gatttatcag caggatgcga tgacctttaa ctttggcgaa
    30421 ctggccgaga aaatgggtca gccgctgcgt gttttcggca acctgcctta taacatctcc
    30481 acgccgttga tgttccatct gtttagctat actgatgcca ttgccgacat gcactttatg
    30541 ttgcaaaaag aggtggtgaa tcgtctggtt gcaggaccga acagcaaagc gtatggtcga
    30601 ttaagcgtca tggcgcaata ctattgcaac gtgatcccgg tactggaagt tccgccgtca
    30661 gcctttacac caccacccaa agtggattcc gccgtcgtgc gcctggttcc tcatgcaacg
    30721 atgcctcacc cggttaaaga tgttcgtgtg ttgagccgca tcaccaccga agcctttaac
    30781 cagcgtcgta aaaccattcg taacagcctc ggcaacctgt ttagcgtcga ggtgttaacg
    30841 ggaatgggga tcgacccggc gatgcgagcg gaaaatatct ctgtcgcgca atattgccag
    30901 atggcgaact atctggcgga gaacgcgcct ttgcaggaga gttaacgatg atcaattcgc
    30961 cccgagtgtg tattcaggtt caaagcgtct acattgaggc acaatcttca cctgataatg
    31021 aacgttacgt ttttgcttat accgtaacca tacgcaatct ggggcgagcg ccagtgcagt
    31081 tgttggggcg ttactggctg atcaccaatg gcaatggccg tgaaaccgaa gtccagggcg
    31141 aaggagtggt tggcgtccag ccacttatcg cgcctggcga agagtaccag tacaccagcg
    31201 gtgcaatcat tgaaaccccg ctgggcacca tgcagggtca ctacgaaatg atcgatgaaa
    31261 atggcgtccc tttcagcatc gacattcccg tattccgact cgccgttccc acactcattc
    31321 attaaaagaa tatggcgaca taccttattg gcgacgttca tggttgttac gatgaactga
    31381 tcgcattgct gcataaagta gaatttaccc ctgggaaaga taccctctgg ctgacgggtg
    31441 atctggtcgc gcgcgggccg ggttcgctgg atgttctgcg ctatgtgaaa tccttaggcg
    31501 acagcgtacg tctggtgctg ggcaatcacg atctgcatct gctggcggta tttgccggga
    31561 tcagccgcaa taaaccgaaa gatcgcctga caccgctgct ggaagcgccg gatgccgacg
    31621 agctgcttaa ctggctgcgt cgccagcctt tgctgcaaat cgacgaagag aaaaagttgg
    31681 tgatggccca cgcagggatc acgccgcagt gggatctaca gaccgccaaa gagtgcgcgc
    31741 gcgatgtaga agcggtgcta tcgagtgact cctatccctt ctttctcgac gctatgtacg
    31801 gcgatatgcc aaataactgg tcaccggaat tgcgggggct gggaagactg cgttttatca
    31861 ccaacgcctt tacccgtatg cgtttttgct ttccaaacgg tcaactggat atgtacagca
    31921 aagaatcgcc ggaagaagcc cctgccccac tgaaaccgtg gtttgcgatt cctggccctg
    31981 tcgctgaaga atacagcatc gcctttggtc actgggcatc gctggaaggc aaaggtacgc
    32041 cggaaggtat ttacgcgctg gataccggct gctgctgggg tgggtcatta acctgcctgc
    32101 gctgggaaga taagcagtat tttgtccagc cgtcgaaccg gcataaggat ttgggcgaag
    32161 cggcggcgtc ttaaacacag cctgatatag gaaggccgga taagacgcga ccggcgtcgc
    32221 atccggcact agccgtaaat tctatacaaa attaccgccg ctccagaatc tcaaagcaat
    32281 agctgtgaga gttctgcgca tcggcgtcgt ggaattcgct gaataccgat tcccagtcat
    32341 ccggctcgta atccgggaaa tgggtgtcgc cttccacttc tgcgtcgata tgcgtcagat
    32401 acagtttttg cgcttttggc aggaactgct cataaacgcg accgccgcca atcaccatga
    32461 tttctggtac gtcaccacac gccgcgatgg cttcatccac cgacttcacc cacgttacgc
    32521 gatcgtccgt acccggttga ctgctgagga taatattttt gcgtcctggc aacggacgac
    32581 cgattgattc ccaggtatgg cggcccataa tcacgggttt atttaaggtg ttgcgtttaa
    32641 accaggcgag atcggcaggc aggttccacg gcatggcgtt ttccatgccg ataacgcgat
    32701 ctaccgctaa cgccgcaatc agactgatca ttgagatttc ccgataaaaa aaattgtcgc
    32761 cactatacgt aaagcgtaaa ccgtcgtcga ctggtgcgag gatgatgttg aggaaaattt
    32821 tatattctgc tggcgagtcc acgctctctc cctggactcg ccgcattaca atgaaacaaa
    32881 aacaaacagt tagctgtaaa gtgtgattta cgtcactctt tattaggatg agggtttcgt
    32941 ttccggttca tccgccatgt tgccggtatg tttaccttct tcggttccct gccagccatg
    33001 tcgttgaatt aatgacagat gttcgcgatc ctcggtaatg atctcactta acatcgcgct
    33061 ggtgcgttta tagaccgccg cgcgggcttt ggtatcattc tcaaccattg ccatctcttc
    33121 caccatctga atattaaagc ggcggaacac atcggcacgt tctcgcgctt catacggccc
    33181 cagacctaaa ctttccagtg ccagacgccc ggttttcagc gcaccttcga aggtttcacg
    33241 ctccggcttt tcaacgcctg cctgacgcaa acgaatgtag tggtcgacat cgcgggcgcg
    33301 ggcaataatc tgcaaatgcg ggaaatgttc tttcaccatc tctgtcagtt gcaggttggt
    33361 ttgcggatcg tcgatggcgt taatcagcac ttccgctttc gccgctccgg cagattccag
    33421 taaatccatc cgcgtggcat cgccataaaa cactttcata ccaaatttac gcaaggtttc
    33481 gatatggtcc ggatcgtgat cgagtaccac cattttcacc ccgctggaga gcagtaaacg
    33541 tccggtaatc tgcccaaaac gaccgaatcc ggcgataatc acgcgcggct gttcttcgtc
    33601 gatctcatcg gcttcacgcg cttcctcagt agaagattgc tcaaggcgat tgaggatcac
    33661 cagcagaatc ggcgttgctg ccatcgacag cgccaccgcc agggtcagcg atttcgccca
    33721 ctccggctcc agcacattcg ccatctgcgc cgcgccaaat accacaaagg caaactcact
    33781 gccctgccct aacaacaccg caaaccaacg acgctgttta tttggcactt gcaacggtcg
    33841 ggcaatcagc cacagcatgg cgattttgat gatgaggaaa ccgagcagca aaatgacaat
    33901 gcgcaatggg ttttcaagca gcgtgccaaa gtctatcgac atgccaacac cgatgaaaaa
    33961 cagccccaac agcaaacctt taaatggttc gatatcgctc tccagcgcat gacggtattc
    34021 cgagcttgcc agcagtacgc ccgccagaaa cgcgcccatc gccatcgaca agccgacctc
    34081 ttccagcagc aaaccaaagc caaacacgag gaataacgcc acggcactaa acacttcccg
    34141 caagccagag cgggctacaa aacgcagcgc cggacgcgtg acatagcgcc ccagcaatac
    34201 caccagcacc agcgcacccg ccacttttaa cgccgagaga gcaaatgcgc ccatcgtcgt
    34261 cgaggcactg ctcgttgcca gtagcggaat catcgccacc agcgggatcg ccgcgatatc
    34321 ctggaacagc agcaccgcaa aggcactgcg acccatttgc gtcaccatca gattgcgttc
    34381 attcatcgcc tgcatggcaa tcgccgtaga ggagagcgcc agcgtcatgc cgatcaattc
    34441 cgcgacctgc cagcgcagcc caagtaacat gcagaacagc cccagcaggc cgccgcaaat
    34501 caccatctgc aatgcgccac cgccgaacac tgccgcacgc agcttccaca gcctttgtgg
    34561 atcgagttcg aggccgataa taaacagcat cagcaccacg ccaatctcgg caaagtgcag
    34621 aatagattcg gcatcggtca ccagtcgcag cccccacggg ccaataatga agccggcgat
    34681 caggtagcca agtaccgatc ccagaccaag acgtaccgca atgggtacaa tcagcgctgc
    34741 cgaaccgaga taaatcagcg cctgaatcag cgtatggcta tccatgatgg gcctcctgcc
    34801 attccagcag acgttgctta tagtgacgcg cctgcccttc gagggtttcg tcgtcacaaa
    34861 taaaggtgca gtgcatggca aacggtggca gccagttcag cccgcagtag attgccgtcg
    34921 cctgtagcgg ctgcgacagc acatcaaagc ccggatgcgc accaatttca aaatggcttt
    34981 ccccgccgcc ggtcgtcacc gcccacagca aatgtttgcc atgcagcgcc gtgccgccgt
    35041 gaccgtaagc ccagccgtgc gagaaaactt tatcgatcca aagtttgagg agcggtggaa
    35101 tgctgtacca ctgcatcggg tgctgccaga cgatcagatc ggcgcgagac agcgcctcct
    35161 gctcggcggc aatatcgata ttgaagtcag gatagagttg ataaagagag cgaatttcga
    35221 cgccttccag cgtccttgcc tgttcaagca tccgtttatt cgcatgggaa tgatgcggat
    35281 acggatgcgc ataaattata agaatcatag gtagcccgcg tgattacgcc tttgttttcc
    35341 cacaaagtgt agtcatatat tcacgcggct tatagtcaat aatattgatt cagaaaagag
    35401 agaaatctga acaatttacc ccattctctg cccgcggatc gtcatattgc tggtttgcgc
    35461 cagtgacatc cctcgagtct ccggggcaaa cgctacggaa atcaacaagc caaacagcga
    35521 gatacccgcc cccattagca tcgtgttact gataccgtaa ttattgataa agatcggcag
    35581 tgcccaggtc gaaacaatgg tgccaatacg gcttaaggac ataatcacgc ccacggcaga
    35641 ggcgcggata tctgtcggga agagttcatt aggatagagc cactgcaaat tacccggccc
    35701 gccagagaaa aaggcataca ccgcaaaggc catcactacc agccagatcc ccatatccgg
    35761 gatcagcccc aaaaccgcca gcgccagcgt catcatggca aagctgccaa tcaacaatgg
    35821 acgccgtccg gcagtgttta accacagcat cggcggaata cagccgagca taaagaacag
    35881 gctaatcacc acgttcccca gcgccgcgtt tttgccaaca cccaatccca acaaaccaac
    35941 gatttgcggg ccaaaggtgt aaatggcgaa cattgggatc acctggcagg tccagatggc
    36001 ggcaacaaac agaacaaaag gaaaatggcg gcgattaaac agatcgcgaa aacgggtttg
    36061 ctgcggttgc tcttcatcga aagccaccgg ttcgccaaac agttttatca tcatctcttc
    36121 gcactctttt actcgccctt tgcgtaataa ccagcgggga gattcaggca gttcgaatcg
    36181 accaatcaaa atcaacaaac aggggatcgc cgcgctaccc agcatccagc gccagccgcc
    36241 ttccacatca taaagccagt agccgaccag atcggcgcag gtcgcgccga cataccacat
    36301 ggcggcgata aagctgatgg aaaacgcccg ctgacgggta ctggagaact cggtgatcat
    36361 tgaggtggcg atgggataat ctgcaccgat gacaatgccg ataagtaccc gcatcaccaa
    36421 cagttcgacg ggggatgaaa caaacatcgt cgccaccgat atcacgccga tggcgatgat
    36481 atcaatgagg aacattttgc gccgtccgac tttatcggaa atatagccaa acagcgatgt
    36541 gccaacgaac agcccggcga gcgttcccgc gcccaacaag ccaatccagt cagcgtccag
    36601 ttttagcgcc ggagtcagtt gctccagcgc cacgccaatc attaccagta cataaccatc
    36661 cagaaacgga ccaccgcttc cccacagcaa aatgcggcgg tgaattgagg agaatttgag
    36721 atcgtcaaag tttctggacg gttgcatggg ttattcctgt ttttttgcaa tgagagtcag
    36781 tacggcgtta cgtatcaaac caacatcagc cgtaacggaa ctccacacca aaggtgccgc
    36841 gcgggtattc ccactgttcc agcgccgacc ccagccccag aatgcgacag gtgccgcact
    36901 ccagacatcc ggcgtaatcg aagcgcacac tgccgtcatc ctgcttcttg tacagacctg
    36961 cggggcacgc tttcaccagc agctccaggg cctgtttatc ggcatcggcc ttcacaacaa
    37021 tgtgcggatg ctcttcatcg acattgaatt tattgacgcc cagtttgacg tccacattga
    37081 cgggagaagt cataaaacgg tcactccttt catgccatcc ttgatcagat tgatgaagcc
    37141 cactttcttg ccgtggcgga ggattttctt gcgcatcagt tccggcgcac tgccgtcaat
    37201 ggtgaacagg tcacgcgcca cgcccaccgc cagttccggg tagccgctaa acatgcgtgg
    37261 gttatcaagg aaggccggta gtttctggta catacgcata tcgcgcagcg ggccactctc
    37321 aagatgctga cgatattccg ccagtttttg cttactgaaa tcgtcgcttt tcatcgctga
    37381 aagcacggtt tttgctgcgg cttccccggc ggcaatcgcc agatccatac cgcgaatggt
    37441 aaaaccgagg ttcatacaca ttccggcggc atcaccggca atcaatacgc cgtcaccaac
    37501 caactccggc agcatgttga tgcctgcttc cggcactacg tgagcggaat attccaccag
    37561 cttgccaccc gcgatcagcg gtgcaacggc cggatgttgt ttgaaatctt ccagcatttg
    37621 cggcaccgat ttttttgcgt catgcagatg atgcagacca caaaccagcc ccagcgacag
    37681 ggtattttca ttggtataaa ggaagccgcc gcccatcagg ccatcggtgg gtgatcccgc
    37741 aaacagacaa gccgcgccct gattaccctg caactgaaaa cggtcttcga ttaccgactt
    37801 cggtaactcg atcagttcct tcacgccaac cgccacatcc gtcggtttaa cgcgttttgc
    37861 catccccagc ttttcggcaa ggatggagtt cactccatca gcaaggatca ccgttttcgc
    37921 ttcaatcaca tcgccatcgg cttctacacc gacgactttg ccatcgcgct gtacgaggtt
    37981 atcgacgcgg atcccggtaa ttaactgcgc gcccgcttct tcggcctgct ccatcagcca
    38041 ggcatcaaat ttactgcgca aaacggagta agaacgctgg gatggcgagg tttcgtcacc
    38101 attgcagtag tccatagtca tcgctgactt ttccgtcata aacgcgagtt tttcatgggt
    38161 gatcaggcgt tctacggggg cggagtcggc gaaaccagga ataatgtgtt ccaggctgtg
    38221 ggcatagaga cgcccgccgg tgacgttctt ggcacctgcg gaattgccac gctcgataac
    38281 taacacttgc gccccttcgc gggcgagcac cagtgcggca accgaaccgg caagcccagc
    38341 accgacgatg atggcgtcaa agatatcttc ggacataaga gctccctgtc agcggcaggg
    38401 ccaaaatgca gccctgccag agtggatcaa cgcgctaaag ctgcggtcag cgccggaagg
    38461 atcttcacgg cgtcaccaac aatgccgtaa tccgcgtact ggaagatcgg cgcattttta
    38521 tctttattga tggcgaaaat ggtttgcgat gcattagcac caaccatgtg ctggatctgc
    38581 ccggagatcc ccaccgccag gtacagttca ggtttcagca tcaggttgga gataccgaca
    38641 tagcgttcgt gctccatcca tttttcgttt tccgccaccg gacgagaaca ggccaactcc
    38701 gcacctatcg ccttgcaaag ctgttctgcc agcgcaatgt tctctttgct gccaataccg
    38761 cgaccgacgc tgaccaccag acgggctttg tcgagatcga cgctgttgct ctggcgcgcc
    38821 tgggttgccg tgcgggtaat cgccacagcc ggagcctgcc actccacggt gtgcgtttcg
    38881 ccagtgcgtg acgcgtctgg ctgagccgca tcgaacgtgc cgctgctgat ggtcagtacc
    38941 gcatacggcg tggcaatgcg ttcttcgcca atcgccagac caccgtaaac catgtgtttc
    39001 actgtcgctt taccgtcctg tacgctgacg gtgctggcat cgttagacac cgccgcttta
    39061 aggcgataac ccagttttgc cgccagtaat ttgccgcgac gggtgtttgg cagcagcacc
    39121 aggccgtctg cgccgtgctg gcgaatagtg tcagccatga caccggcgta atcttcgatc
    39181 atccgatcgt ccggtttgcc gtttaatttc cagacatgat tagcgccgag ctggattgcc
    39241 tgtacgccgt cggcatcatt gaggacaaag gtgttgattt gattagctaa agcctgcgca
    39301 ccgttcatca gttccggcag acgagaaggg gtatcgctga atacccagac ttgagaaaac
    39361 gtgttcatag catcccctgt aattaaatga ctttgcgaag attttcagca aatgcggcga
    39421 tctgttcttc gccgtcgcct tcaatcacga tgcgctgacg ttcgcgctgt ttcggcgcgg
    39481 caacctgttg ttctgaccag gctgcctctg cgttaaaacc aatatccgcc gccgaccata
    39541 cctggacggg ctttttcgcc gcgccgagaa tggctttcat cgaaggaatt tgtggggagt
    39601 tgatatcagt ggaaacagca acaaccgcag gcagcggaat gcttaaggtt tcggtttcat
    39661 cttccagttc gcgctcaacg gtgagggtat ctgcagtcag ggagataatt ttgctgacgc
    39721 cgttaactgc cggaatattg aggatttcgc ccaccagcag accaacctgc tgggcataaa
    39781 ggtcggaaga accatcgcca cagaggatca aatcaaagcc tgctttctgg gcggctgcag
    39841 ccagtgcgct cgccgtttgt tgcggcagtg cctgctcgaa ctggtcatca atcaccacaa
    39901 tcagttcatc cgggccgcgc gatagcacat ctttacgccc tttggcgttg gtcagggctt
    39961 taccgcccac acttaaggcc gtcacctgcg cctctgctgc ctgttgcttt agctggcaag
    40021 ccgcttcaat agcgttcaga tcgtattggc ttattttggc atcggctttg ctgaagtcta
    40081 atgaaccatc agcattattg accgcaatat cctgttcatc aggcacgcac ttatagcaag
    40141 taataatctt cattgcatct ccagaaatca tgaaggaaac gtcgttcata tcggtggtgt
    40201 taattacaga tatcacgccc tttaatttgg aaataaaact ttaatcacca atattgaaaa
    40261 tgtcacacgc agataaatcc aactttcaat attgttaagt tcctcaccaa tattgaaaac
    40321 atggcgtagc aaaaagaaat tttcaatatt gctttatgga tcaccaatat tgaaagtcag
    40381 atgctatttt tttactcaca acacaacata acaaactgat taataatcaa aattaacgag
    40441 aaaagcgccc tctattcacc cgaaacaaaa atgtgataac aatcacagaa tgcagcttat
    40501 tgaataccca ttatgagtta gccattaacg cgtccacgag gttaataata attatattaa
    40561 atgttaacaa aaataaaaca aacgggaacg caaaataaat attcgttttc acagtggaat
    40621 taactcatga agaatgaaaa gagaaaaacg ggaatagaac cgaaggtttt ctttccgccg
    40681 ttaataatcg tcggcatact ttgttggctt acagtcagag atctggatgc agcgaatgtc
    40741 gttattaatg ctgtattcag ttacgtcacc aatgtatggg gatgggcatt tgaatggtat
    40801 atggtggtga tgcttttcgg ttggttctgg ctggtgtttg gcccgtatgc caaaaagcgt
    40861 ttaggtaacg aaccacctga atttagtacc gccagttgga tctttatgat gttcgcctcc
    40921 tgtacgtctg ctgccgtact gttctgggga tcgattgaga tctactacta catctccacc
    40981 ccgccgtttg gcttagaacc gaactcgaca ggggcgaaag agttggggct ggcttacagc
    41041 ttgttccact ggggacctct gccgtgggcc acttacagct tcctttcagt cgccttcgct
    41101 tacttcttct ttgtccgcaa aatggaagtg attcgcccca gctcgacact ggtgccgctg
    41161 gtaggtgaaa aacacgccaa agggttgttc ggcactatcg tcgacaactt ctatctcgtc
    41221 gccttgatct tcgcgatggg taccagtctg ggccttgcca cgccgctggt gaccgagtgt
    41281 atgcaatggt tgtttggcat tccgcatacc ctgcaactgg acgctatcat cattacctgc
    41341 tggattatcc tcaacgccat ttgcgtcgct tgcggtctgc aaaaaggggt acgtatcgcc
    41401 agtgacgtgc gtagttacct gagcttcctg atgctgggtt gggtgttcat tgtcagcggt
    41461 gccagcttca tcatgaacta cttcaccgat tcggtgggga tgttgctgat gtatctgccg
    41521 cgcatgttgt tctataccga tcccatcgct aaaggcggct tcccgcaggg ctggaccgtg
    41581 ttctactggg catggtgggt gatttatgct atccagatga gtatcttcct cgcccgcatc
    41641 tcccgtggtc gtactgtgcg tgaactgtgc ttcggcatgg tgctggggct gacagcgtca
    41701 acctggatcc tgtggactgt actcggtagt aacactctgc tgttgataga taaaaacatt
    41761 atcaacattc caaatctgat cgaacagtac ggtgtggcgc gcgccattat cgaaacctgg
    41821 gccgctctgc cactcagcac cgccaccatg tggggcttct tcatcctctg ctttattgcc
    41881 accgttacgc tggttaacgc ctgctcttat accctggcga tgtccacttg ccgcgaagta
    41941 cgcgatggtg aagaaccacc gctgctggtg cgtatcggtt ggtcaattct ggttggcatt
    42001 atcggtattg ttttgctggc gctcggcggc ctgaaaccga ttcaaactgc cattatcgcc
    42061 ggaggatgcc cgctgttctt cgtcaacatt atggtgacgc tctcctttat taaagacgcg
    42121 aaacagaact ggaaagatta attaaccccc aaaatatcaa gaggttgaaa gatggatttt
    42181 aatttaaatg atgagcagga actgtttgtc gccggtatcc gcgaactgat ggccagcgaa
    42241 aactgggagg cctattttgc cgagtgcgac cgtgacagcg tctacccgga acgttttgtc
    42301 aaagcactgg cggatatggg tatcgacagt ctgctgatcc ctgaagagca cggtggtctg
    42361 gacgcggggt ttgttactct cgccgccgtg tggatggagc tgggacgtct gggggcacca
    42421 acctatgtac tgtaccagtt gccgggcggg ttcaacacct tcctgcgcga aggcacacaa
    42481 gagcagatcg acaagattat ggctttccgc ggcaccggta agcagatgtg gaactcagcg
    42541 attaccgaac cgggcgcggg ctccgacgtg ggtagcctga aaacgactta tacccgtaga
    42601 aatggtaaga tttatcttaa tggtagtaag tgttttatta ccagcagcgc ctacaccccg
    42661 tacatcgtgg tgatggcgcg cgacggggct tctccggaca aacctgtcta caccgaatgg
    42721 tttgttgata tgagcaaacc gggcatcaaa gtgaccaaac ttgaaaagct cggtctgcgt
    42781 atggatagct gctgtgaaat cacctttgac gacgtggaac tggacgagaa agacatgttc
    42841 ggtcgggaag gtaacggctt taaccgcgtc aaagaagagt tcgaccatga acgtttcctg
    42901 gtagccctga ccaactacgg tacggcgatg tgcgcctttg aagatgcggc gcgctacgcc
    42961 aaccagcgcg tgcagtttgg cgaggctatt ggtcgtttcc agttgattca ggaaaaattc
    43021 gcccacatgg cgatcaaatt aaactccatg aaaaacatgc tgtatgaagc agcgtggaaa
    43081 gcagacaacg gcaccatcac ctctggcgat gcagcgatgt gcaaatactt ctgcgccaat
    43141 gcggcatttg aagtggtgga tagcgcaatg caggtgctgg gcggtgtcgg gattgcgggc
    43201 aaccaccgca tcagccgctt ctggcgtgac ctgcgtgtag accgcgtctc cgggggatct
    43261 gacgaaatgc agatcctgac gctgggtcgt gcggtgctga agcaataccg ctaagtcaat
    43321 gcgctgcctg atgcgacgct gatgcgtctt atcaggccta cgggagcacg aatgtaggcc
    43381 ggataaagcg tttacgccgc atccggcagt catgcgctac ataaattttt caggagcaaa
    43441 taatggatca tctacccatg ccgaaattcg ggccgttggc cggattgcgc gttgtcttct
    43501 ccggtatcga aatcgccgga ccgtttgccg ggcaaatgtt cgcagaatgg ggcgcggaag
    43561 ttatctggat cgagaacgtc gcctgggccg acaccattcg cgttcaaccg aactacccgc
    43621 aactctcccg ccgcaatttg cacgcgctgt cgttaaatat tttcaaagat gaaggccgcg
    43681 aagcgtttct gaaattaatg gaaaccaccg atatcttcat cgaagccagt aaaggtccgg
    43741 cctttgcccg tcgtggcatt accgatgaag tactgtggca gcacaacccg aaactggtta
    43801 tcgctcacct gtccggtttt ggtcagtacg gcaccgagga gtacaccaat cttccggcct
    43861 ataacactat cgcccaggcc tttagtggtt acctgattca gaacggtgat gttgaccagc
    43921 caatgcctgc cttcccgtat accgccgatt acttttctgg cctgaccgcc accacggcgg
    43981 cgctggcagc actgcataaa gtgcgtgaaa ccggtaaagg cgaaagtatc gacatcgcca
    44041 tgtatgaagt gatgctgcgt atgggccagt acttcatgat ggattacttc aacggcggcg
    44101 aaatgtgccc gcgcatgagc aaaggtaaag atccctacta cgccggttgc ggtctgtata
    44161 aatgcgccga cggctacatc gtgatggaac tggtgggcat tacccaaatt gaagagtgct
    44221 ttaaagatat tggcctcgca catctactcg gtacgccgga aatcccggaa ggcactcagc
    44281 ttatccaccg tatcgaatgc ccttacggcc cactggtaga agaaaaactc gatgcctggc
    44341 tggcggcaca taccatcgca gaagttaaag aacgctttgc cgaactgaat atcgcctgtg
    44401 ccaaagtact gaccgtaccg gaactggaaa gcaatccaca gtatgttgcc cgtgaatcaa
    44461 tcactcagtg gcaaacgatg gatggtcgca cctgcaaagg gccgaacatc atgccgaaat
    44521 tcaaaaataa ccccggacaa atctggcgcg gaatgccctc acatggcatg gacacggctg
    44581 ccattttgaa aaatatcggc tacagcgaaa acgacattca ggagttggtc agcaaaggtc
    44641 tggccaaagt tgaggactaa acgcgtggcg tcagtcggct tgcctgacta gcgcccgccc
    44701 aataacaaac gaacaaaaat ggatagaggt gcaatggata tcattggcgg acaacatcta
    44761 cgtcaaatgt gggacgatct tgcggacgtt tacggtcata aaacggcgct gatttgtgaa
    44821 tccagcggcg gagtcgttaa ccggtatagt tatcttgagt taaatcagga gattaaccgc
    44881 acggcaaacc tgttttatac gctggggatt cgcaaaggcg acaaggttgc actacatctc
    44941 gacaactgcc cggaatttat cttttgctgg ttcgggctgg caaaaattgg cgcgattatg
    45001 gtgccgatta acgcccgcct gttacgcgag gaaagcgcgt ggatcctgca aaatagccag
    45061 gcgtgcctgc tggtgaccag tgcgcaattc tatcctatgt atcaacagat tcagcaggaa
    45121 gatgccactc aattgcggca catttgcctg acagatgtgg cacttcccgc tgatgatggc
    45181 gtgagttcgt ttactcaact gaaaaatcaa caacctgcca ccttgtgcta tgcaccgccg
    45241 ctatcgactg acgatacggc ggaaattctc ttcacctccg gcaccacctc ccgaccgaaa
    45301 ggtgtggtga ttacccatta caacctgcgc ttcgctggat attactccgc ctggcagtgt
    45361 gcactgcgtg acgatgacgt ctacctgacg gtaatgcctg cgtttcatat cgattgccag
    45421 tgtactgcgg cgatggcggc gttttctgcc ggggccacct ttgtgctggt cgagaaatac
    45481 agcgcccgcg ccttctgggg acaggtgcag aagtaccgcg ccaccattac cgaatgtatt
    45541 ccgatgatga tccgtacgtt gatggtgcag ccgccttcag cgaacgatcg gcaacaccgc
    45601 ctgcgggaag tgatgtttta tctcaacttg tcggagcagg aaaaagatgc gttttgtgaa
    45661 cgcttcggcg ttcgcttgct gacgtcttat gggatgacgg aaaccattgt gggcattatc
    45721 ggcgatcgcc ctggcgataa acgacgctgg ccgtcgattg gtcgggcggg gttttgctac
    45781 gaagcggaga tccgcgacga tcacaatcgc ccgctcccgg caggtgagat cggtgaaatc
    45841 tgtattaaag gcgtaccagg gaaaaccatc ttcaaagagt attttctcaa cccgaaagcc
    45901 actgcgaaag tgctggaagc cgacggctgg ctacataccg gcgataccgg atactgcgac
    45961 gaagagggct ttttttattt cgtcgatcgc cgctgcaata tgatcaaacg cggtggcgag
    46021 aatgtctcct gcgtggagct ggaaaatatc atcgccaccc atccaaaaat tcaggatatc
    46081 gtggttgtgg gtattaaaga ttcgattcgc gatgaagcca tcaaagcatt tgtggtgctg
    46141 aatgaaggtg aaacattgag cgaagaggaa tttttccgct tctgcgaaca aaatatggcg
    46201 aaatttaaag tgccctctta tctggagatc agaaaagatc tgccacgtaa ttgctcgggg
    46261 aaaataatta gaaagaatct gaaataaatg aaacagcagg gaactaccct gccagctaat
    46321 aatcacgcta taaaacaata tgcatttttt gcagggatgt tgtcgtccct gaaaaagcaa
    46381 aaatggagaa aaggaatgag tgaatcatta catctgaccc gcaatggatc aattctggaa
    46441 attacccttg atcgtccaaa agcgaatgct attgatgcaa aaaccagctt tgaaatgggc
    46501 gaagtatttc taaatttccg tgacgatccg caattacgtg tcgccattat taccggtgcc
    46561 ggagagaagt tcttttccgc gggctgggat ttaaaagcgg cagcagaagg cgaagcaccg
    46621 gatgctgact ttggcccggg tggatttgcg ggattaaccg aaattttcaa tctcgacaaa
    46681 ccggttatcg cagctgtgaa cggctatgcc tttggcggcg gctttgaact ggcgctggcg
    46741 gcagatttta ttgtttgtgc cgataatgcc agcttcgccc tgccggaagc caaactgggc
    46801 atcgttcctg acagcggcgg cgtgctgcgt ctgccgaaga tcctgccgcc tgccatcgtc
    46861 aatgaaatgg tgatgaccgg cagacgaatg ggcacagaag aggcgctgcg ttgggggata
    46921 gtcaaccgcg tggttagcca ggcggaactg atggataacg cccgcgaact ggcgcagcag
    46981 ctggttaaca gcgccccgct ggcgattgcg gcgctgaaag agatctaccg caccaccagc
    47041 gaaatgccgg tagaagaagc gtatcgctat attcgcagcg gcgtgttgaa acactatccg
    47101 tcggttctgc attcggaaga tgccgttgaa gggccgctgg cgtttgccga gaagcgcgat
    47161 ccggtatgga aaggacgtta acaaccgtga gctattacgc ctttgagggg ttaattccgg
    47221 tggttcaccc gacggcgttt gtccatccca gtgccgtctt gattggcgat gtgattgtgg
    47281 gagccggtgt ctacatcggc ccactcgcct cactgcgtgg tgactacggg cggttgatcg
    47341 tgcaagcggg agccaatatt caggatggct gcattatgca tggctactgc gacactgaca
    47401 ccatcgttgg ggaaaacggc catatcgggc acggagcgat cctgcatggt tgtgtgattg
    47461 gtcgcgatgc attggtcggg atgaacagcg tgattatgga tggcgcggtc attggcgaag
    47521 agagcattgt tgccgccatg agctttgtca aagcaggctt tcacggcgag aaacgccagt
    47581 tgttgatggg tacgccagcc cgcgctgtac gcagtgttag tgacgacgag ttacactgga
    47641 aacggttgaa taccaaagag tatcaggatc ttgtcgggcg ctgtcatgca tcgttacatg
    47701 aaacacagcc actgaggcaa atggaggaaa atcgcccccg tttgcagggg acgacggatg
    47761 tgacgcctaa acggtgatct tgccggatgc gacctggttg ctggataaga tgctacaaca
    47821 tcgcatctgg caagcaggac gcccggtatc aacgagataa aattaacgac gcatactctt
    47881 tgacaacatc atctgccact tctgctcgcg gttaagttcc gtgagcggaa cggcaggaat
    47941 acgcggcgtc tttcttacgc cgactaattt atcccggctg ttattgcgca ggcgcgcgta
    48001 aatttgctca tcgatatcga ccacttttac cagtcgctgg cactggcatc cccgtccttc
    48061 cagcttatta gggatcatct taacttcgca gcttatttct gcgacttccg acagaatata
    48121 agtcagggta ttaaccgcct tgctgtgttc aatatcgaaa tgaatagaga tctctcttgc
    48181 tatcacccac cgattttcag ccatcatcca ttcggcgatt aacaagtaga gtggtttttc
    48241 aacatatcct tcacacatac gaactccagt ttcacaaatt aaaagtctgg ctatgactcg
    48301 ttttgaagca attaaacaag gccatattaa aattgtggat atatcgatag tatgcaactt
    48361 caccgtcgat aagtgtgagc taaatcctgc ttatgtcatc aaaaatatcg attccccaaa
    48421 agatttactt aatgggcaaa aaaaacggtc ctcatcagag aaccgtatta cttattcgat
    48481 caaattagcg gatgaaaaat atccgccatg acacgctatt atttgatctg cgcgtgcatt
    48541 tcctgcaccg aaattacttt ttcggtcgcg tcggcattca gcgccatcgc ggtagcgaaa
    48601 ccaccgttca gggtggtgtc ataatgcact ttatattgca gcgcactgcg acggatcacg
    48661 cgggagtctt caatcgcgcg acggcctgaa gtggtgttga tgatgtaggt atattcgcca
    48721 ttcttgatgc ggtcctgaat gtgcggacgg ccttcatgca ccttgttcac cagacgcgga
    48781 ttaatgcccg cttcgcccag cacaatcgcc gtgccgtggg tcgcatccag ctcgaagccc
    48841 tgtttcagca gttttgccgc caggtccacc acgcgttctt tatcgccttc gcgcacggaa
    48901 agcaacgcac gaccgtgttt cttcatggtg gagttgctgc ccagctgcgc tttggcaaac
    48961 gcttcagcga aggtgcggcc cacgcccatc acttccccgg tggagcgcat ttctggccct
    49021 aacagcgggt caacacccgg gaatttattg aacggcagca ccacttcttt caccgagtag
    49081 tacggcggga taacttcttt ggttacgccc tgctcagcca gcgatttgcc agccatcaca
    49141 cgcgccgcca cttttgccag cggtacgccg gtggctttgg agacgaacgg aacggtacgc
    49201 gccgcacgcg ggttaacttc aatcaggtag acttcgttgt ttttcaccgc aaactgcacg
    49261 ttcatcagac cgcgcacctg caattcgaag gccagtttct gcacctgctg gcgcatcaca
    49321 tcctgaattt cctgacttaa ggtgtaggct ggcagagaac atgcggagtc accggagtgc
    49381 acgcccgcct gctcgatgtg ctccatgatg ccgccaatca gcaccatttc gccgtcgcag
    49441 atggcatcca cgtcaacttc taccgcgtca tcaaggaagt gatccagcaa cactggcgca
    49501 tcgttagaca cgctgaccgc cgtctggaag tagcgacgca ggtcagcttc gtcatagacg
    49561 atttccatcg cccgaccgcc gagaacgtaa gacggacgta ccaccagcgg gtagccaatc
    49621 tctttcgcct tctctaccgc catttcaata gcggtaacgg tggcgttcgc cggttgtttc
    49681 agtttcagac gctcaaccgc atgctggaag cgttcacggt cttctgcacg gtcgatagca
    49741 tccgggctgg tgccgataac cggtacgcca gcagcttcca gcgcgcgcgc cagtttcagc
    49801 ggggtctgac cgccgtactg aacgataacg cctttcggct tctcaatacg cacgatttct
    49861 agcacatctt ccagagttac cggctcgaag tagaggcgat cggaagtgtc gtagtcggtg
    49921 gagacggttt ccgggttaca gttaaccata atggtttcgt aaccgtcttc gcgcagcgcc
    49981 agcgaggcgt gtacacagca gtagtcgaat tcgataccct gaccgatacg gttcgggccg
    50041 ccgccgagaa ccatgatttt ttcacggtcg gtagacggat tcgcttcgca ctcttcttca
    50101 taagtggagt acatgtaagc ggtgtcggtg gcgaactctg ccgcacaggt atccacgcgc
    50161 ttataaaccg ggtgcaggtc atactggtcg cgcagcttgc ggatttccgc ttcgcgcacg
    50221 cccgccagtt ttgccagacg cgcatcggca aagcctttgc gtttcagctg gcgcaggaat
    50281 tcagcgttca ggccagtgat gcccacttcc gctactttct cttccagacg caccagttct
    50341 tcaatctgta ccaggaacca gcggtcaata ttggtcaggt tgaacacgcc gtccacagac
    50401 aggcccgcac ggaaggcatc ggcgatgtac cagatacgct ctgcgccagc atctttcagt
    50461 tcgcgacgga ttttggttaa cgcttccggg tcatcgaggc tcactttcgg gtcgaatcca
    50521 gtcgcaccga cttccaggcc gcgcagcgct ttttgcaggg attcctgctg cgtgcgacca
    50581 atcgccatca cttcgccaac cgatttcatc tgagtggtca gacggtcgtt agcaccagcg
    50641 aatttttcga agttgaagcg aggaatttta gtaaccacat agtcgatgga cggctcgaag
    50701 gaggccggag tacgtccgcc agtgatgtcg ttcatcagtt cgtcgagggt gtaacccacc
    50761 gccagtttcg ccgccacttt agcaatcggg aaaccggtcg ctttcgacgc cagcgccgaa
    50821 gaacgggaca cgcgtgggtt catttcgata acaatcaggc gaccgttttt cgggttcacc
    50881 gcaaactgga cattggaacc accggtttca acgccgattt cacgcagcac cgccatcgag
    50941 gcgttacgca tgatttgata ttctttgtcg gtcagcgttt gggctggcgc gacagtgatg
    51001 gagtcaccgg tatggatgcc catcgcatca aagttttcga tagagcagac gatgatgcag
    51061 ttgtcgtttt tatcacgcac cacttccatc tcgtactctt tccagccgat cagcgactca
    51121 tcaatcagca gctctttggt tggggagaga tccagaccgc gggcgcaaat ttcttcaaac
    51181 tcttcgcggt tataagcgat accgccgccg ctaccgccca tggtaaagga tgggcgaata
    51241 atgcacggga agcccacgtc agcggcaacc gccagcgctt cttccatcgt gtgtgcgata
    51301 ccggaacgcg cggtttccag accaattttc ttcatcgcta cgtcgaaacg acggcggtct
    51361 tctgctttat caatcgcatc ggcggtcgca ccaatcatag tcacgccgaa ctcttccaac
    51421 acgccctgac gctccagctc cagcgcgcag ttcagcgccg tctgaccgcc catcgttggc
    51481 agcaccgcgt ccgggcgctc tttttcaata atcttgcgta ctacttccca gtgaatcggc
    51541 tcgatgtagg tcgcatcggc catttccggg tcggtcatga tggtcgccgg gttggagttc
    51601 accagaatga cgcggtaacc ctcttcgcgc agggctttac atgcttgcgc gccagagtag
    51661 tcaaactcac acgcctgacc gataacaatc gggcccgcac ccagaatcag gatacttttt
    51721 atatctgtac gttttggcat ggctctttta ctcctgatta cttagcggtt ttacggtact
    51781 gctcaattaa ctcgataaag tggtcgaaca acggcgctgc gtcgtgtggc ccagggctgg
    51841 cttccgggtg accctggaag ctgaacgccg gtttatcagt gcgatgaatg ccctgtaacg
    51901 taccgtcgaa cagggattta tgcgtgacac gcaggtttgc aggtaatgtt gcttcatcca
    51961 ccgcaaaacc gtggttctgg gcggtgatca tcaccacgtt tttctccaca tctttaaccg
    52021 gatggttgcc gccgtggtga ccaaatttca ttttgacagt cttcgcaccg ctcgccagcg
    52081 ccagcagctg atgaccgagg cagatgccga ataccggaat atcggtttcg aggaatttct
    52141 ggatggcggt aatggcgtaa tcgcacgggg ccgggtcgcc aggaccgttg gagaggaaga
    52201 tgccgtctgg attcattttc agcacatctt ccgcagaagt ttgcgccgga acgatggtca
    52261 ggcgacagcc tctatccacc agcatccgca ggatgttgcg cttggcacca aaatcataag
    52321 ccacgacgtg gaacggcagc tcgtcttctt ttttcgcttc tggcaggccg ccggtcaacg
    52381 tccagctccc ttgtgtccag ctataggctt ctgcggtggt cacttctttt gccagatcca
    52441 tgccattcag acctgggaac gcgcgggctt tttctaacgc caacgccgca tccgggttat
    52501 cgcctgcgat aatgcagcca ttctgtgcgc ctttctcgcg cagtaaacgc gtcagcttac
    52561 gggtatcgat atcggcaatc gccacgatgt tatggcgctt caggtaagaa gagaggtctt
    52621 cggtattacg gaagttgctg gcaatcagcg gcagatcgcg aatcaccaga ccttgtgcat
    52681 gtacctgaga agattcttca tcggcgtcat tagtgccgac attgccaata tggggataag
    52741 taagagtaac gatttgacga gaataggaag gatcagtgag gatttcttga taaccggtca
    52801 ttgaagtatt gaaaacgact tccccaaccg ccgaacctgt tgcccctatg gcccgaccgt
    52861 gaaactgggt tccgtcttcc agaaccaata gcgctgactt aatcaaaaca ccctccagag
    52921 aatattcact cactttattt gcatattaat tcacaatgat gacgtaaatc aatgcaaatc
    52981 tgcttaccga cgaatttctg gcaaacggcg gcattctgga gatatgggcg ctaaaagtca
    53041 acttaatggc gggatttttt atattatttt gtggctcatg catgttttac aggcattaag
    53101 cgacaaaaag atcatataac ctgttctgga aaacgcttgc gcagcaagaa gattgcatga
    53161 aataaaagcg agcagggaaa agtggaccaa atggtcaaaa tttacattaa aacaacaaaa
    53221 accgaagaca aaacatgtaa tttttggcac ttatagacaa tttaaaaaca taacattaaa
    53281 aataaaaggg ccaaaaatta aagcccttta taatcaataa attaaatgtg ttatttttgc
    53341 accataacaa atattttgtg gttacaaact attgagatca agcacatctc gcatatcaaa
    53401 aagaccactt tccttaccac tcaaccacaa agccgatctt accgcgccgt tagcaaatgt
    53461 catgcggctg gacgccttat gagtgatctc cagacgctcg ccaatatcgg caaacatcgc
    53521 ggtatgttca ccaacgatgt cacctgcacg cacggtggca aaaccaatgg tgccaggcac
    53581 acgttcaccg gtgtggcctt cacgactgta gaccgcgcaa tctttcagat ctttatcaag
    53641 ggcgtgggcg atcgcctctc ccattgccag tgcggtgcct gacggcgcat caactttatg
    53701 tctatgatgt gcttcaataa tttcgatatc ggtgtagtca cccatcactt tggctgcttt
    53761 ctccagcagc ttaagcatga cgttaacgcc aacgctaaaa ttggcggcaa agacaatcgc
    53821 aatatcggcg gcggcgtcac gaatcgcctg tttaccggct tcgtcaaacc ccgtagtgcc
    53881 gatcaccatc cctttgccat gctggcgaca aaaagcgaga tggttcagcg taccttccgg
    53941 acgggtaaaa tcgataaaca catcaaaatc atcttttacc gcatcgaggc tgctttgcac
    54001 ggtaacgcct gttttccctg caccagccag ctcaccggcg tcgctgccca gtaaagaaga
    54061 tccttcgcgc tccagcgccg cgcccagctg cacgccttct aatgccagcg ccgcctgaat
    54121 caactggcgg cccatacgcc ccccggctcc cgcgatggca acgcggatgt ttgcatcatg
    54181 catagctatt ctcttttgtt aatttgcata gaccgttttc agagtaacca gcgcatcgct
    54241 acgccgccag ccaaaaacgc tgataattag aaattaatga taaacaggga gggatatcag
    54301 tgaaaggcat gagtcgatga atgactgcat gccaataaca tgtgacaggt tacgacgcca
    54361 gagccagcac ctcagccacc cactgctgga agcctttcac atccagatcc aatgccacct
    54421 gtacattggc tggcttgccc aggcaaccgt cgatatcaac caccgtcgtg cctgaggtaa
    54481 attcgccctg agtttccact gccacaaaac agggtttgag agtgaacagg tccgggcgca
    54541 ccagccaggc gatggcgcag agatcgtgca ttcgcagacc gctttgcata ctgccgctac
    54601 ggtagtggct aaacagtgca tgaagcattt ttccggtgcg attcaactcc ggcaaagtag
    54661 cgagatagtc aggggttaat attgcctgat tggtgacatc cagaccgcac atgacgattt
    54721 cgattccgct acggaagaca caggcagccg cttctggatc ggcagcgata ttaaactcgg
    54781 cgtttggcgt acagttgccg cgtccggcag aaccacccat gatcaccaga cggcgaatat
    54841 acggcttgca ttccgggcat tgtgaaagta acagcgcaat attggttaac gggccgatgg
    54901 ccaccagggt aacaggctct ggtgcacgca tcagggcatc ccgaatcgcc agaaacgccg
    54961 gtatcccgag cggctttcgg ttgtgctcaa caaagtcgta gccagccatt cccgattcgc
    55021 cgtgcacaga tgccgcatca cgcggtgcgc gtaccagcgg cacagcggcc ccttgggcga
    55081 gcggaatctc cgcattccag aaatgcagca gttgcaaggc attacgggta gttttctcaa
    55141 ccgagacatt acccgcgacg gtggtcatca gttgcaggtc gagttcgggg gcaaaaatcg
    55201 cggcggcaat ggcgacggca tcgtcaatgc cggggtcagt atcgaggaag ataggtaaac
    55261 gcatgttttc tccataaaaa atgccggtaa caagaccggc attttcgcat aacttaggct
    55321 gctaatgact taatcgactt cacgaatatc gacacgcagc tctttcggca cttcgaaaac
    55381 aatgttttct tcacggcctt ccagcggaat ggcttcacca ccgcccagct gctgcaaacg
    55441 tgccaccaca ttctgcacca gaatatccgg agccgatgcg cccgcagtca cgccgacgca
    55501 tttaacctct ttcacccact cttcctggat gtctttcgca tcgtcaatca aaaacgcgcg
    55561 tttgcccata cgctgggcca gctccgccag acggttggag ttggaggagt ttttcgaacc
    55621 gaccaccaac acaacttccg cctgttctgc cagggcgcgt accgcttcct gacggttagt
    55681 cgtggcgtag cagatgtcat ctttgcgcgg accgacaatt ttcgggaagc gtttacgcag
    55741 cgcgtcgatc acatcagacg tgtcatccac cgacagcgtg gtctgggtca taaaggagag
    55801 cttctcttcg tttttgaccg tcagtttcca cacatcgtcc ggcgattcga ccagatacat
    55861 tcccccttcc gggttactgt actggcccat tgtcccttcc acttccgggt gcccggcgtg
    55921 accgatgaga atagattctt cgccacggcg actggcgcgg gcgacttcca tatgcacttt
    55981 ggtcaccagc ggacaggtcg cgtcaaatac cgtcaaatcg cgactttttg cttcgttacg
    56041 taccgcctga gaaacaccgt gtgcggagaa aatcaggatc gcgccgtccg gtacttcgct
    56101 aatctgctca ataaagatag ccccacgctc acgcaagcta tcgaccacat agcggttatg
    56161 taccacttcg tgacggacat atatcggtgc gccgtaaatg gccagcgcgt tttcaacaat
    56221 gctgatagcg cggtctaccc cggcacaaaa accacgcggg ttggccaaca ggatctgcat
    56281 gttacgcctc cagtgccgga tcgatttcca gcacttcaat atcaaaatga acggtctgcc
    56341 cggccagcgg atggttgaaa tcaacggtaa tggagtcgcc gttaatttcg cggatcacgc
    56401 caggcatctc actgccatcc attgcggtaa aaagcatgat tgcgccaatt tctggctcgc
    56461 ctgcatccat aaattcacgg cgggagaagt actgaatcag gtccggtgac ggcacgccaa
    56521 acgccgcatc tggctccaac gagaaggtgg ttttatcgcc cactttcagc cccaacaggt
    56581 gttgctccag cccttcagaa agagaagcat cacccaggcg gaacagcgcc ggtttaccgt
    56641 tgttgcgggt agactcggcg gtggtgccat cgtcgagttt tagcgtgaag tgcaccagga
    56701 cggcgctatt gctctgtaca gattcagaca tgcaggtttg ctcttatatt ttgaggattt
    56761 ttgccggatg cggcctacga tttcgcagca atctgtaggc cttatccggc agggtttatt
    56821 attgtttttt cgctttagaa ggcaaaaaac cttccagcac aatcagtgcc gcaccgacac
    56881 aaatggcagt atcggcaagg ttgaaggtgg cgaagtgcca gtcgccgacg tagaagtcga
    56941 tcatatcgac aacgaagccg tgccacaggc ggtcgaacag gttgcccagc gcgccgccaa
    57001 taatcagcgc ataagcgata ttgtttagct tctgcgtggc cttcgagcga tacatcatca
    57061 ctgccaggat cacgctaata ccaatcgcaa taccggcaaa gaaccaacgc tgccagccgc
    57121 cgctatcggc aaggaaacta aacgccgcgc catagttacg cgcataatgc agattaagcg
    57181 acgggaacag cgggaccgta tcccccagag caaagttctg gaggatcagg tatttgctgc
    57241 ccagatcgat aatcagcacg actaccacca gccacagcca gcgtagccct gttgaacaga
    57301 tcgattgact catcaggcaa acttacgttt ttcaccgtca ccggcgacgt tgctgacaca
    57361 gcggccgcag atttctgcgt gttccgccac cttgccgaca tcctgggtgt agtgccagca
    57421 gcgtgggcac ttctcacctt cggctttact caacgcgact ttcagccctt tgagtacttc
    57481 gctctgctga gcatcagcag gtgcgtcgtt atagtctgca acggtagcgc cggaggtcaa
    57541 caggacaaat cgtaattcat cgcccagcgc ggtcagtttc gccgacagtt ccggttctgc
    57601 atacaaggtt actgccgctt ccagcgagcc acccactttc ttgtcggcac gcgcttgctc
    57661 aatgactttg ttcacttcgc cacgcacttt caacagctcg tcccagaacg catcgttcat
    57721 cgcttcactg tctgccaggc caaacaggcc ttcgtaccac tcaccggtga agacgtattt
    57781 ttcacgttcg cccggcaggt agccccacac ttcatcagcg gtgaaggaga ggattggtgc
    57841 catccagcgc accagcgctt ctgcgatgtg atacagcgca gtctggcagc tacgacgcgc
    57901 cacactgtcc gctttggcgg tgtactgacg gtctttgatg atgtcgaggt agaaggaacc
    57961 catctcaacg gagcagaagc gcatcagacg ctgtaccact tcgtggaaat cgtatgcttc
    58021 gtacgccttg aggatgtctt cctgtgccgc tttcgcacaa cctacggccc agcgatccag
    58081 taccaccatc tcttccggtt tcaccatatc ttttgctgga tcaaaaccgt tcaggtttgc
    58141 cagcaggaag cgcgcggtgt tacggatacg acgatagcta tcggcagcac gtttcaggat
    58201 ctcgtcagaa acggccattt caccggtgta gtcggttgat gccacccaca gtcgcagaat
    58261 atccgcgccc agtttgttca tcacatcctg cggcgaaacg gtattgccga tggatttaga
    58321 catcttgcga ccctgaccat ccacggtaaa gccgtgggtc agtacctgac gatacggcgc
    58381 tttgcctttc atcgcggtgg agatcattag ggaagacatg aaccaaccac ggtgctggtc
    58441 agaaccttcc agatacatgt ccgctgcgtg accggcaaat tccggacgca cgtcaacaac
    58501 agaagagtgg gtagatccgg agtcaaacca tacatccaat gtgtccggca ctttcacgta
    58561 ctgatcagct tcatcgccga ggatctcttt cgcatcaaga tcccaccacg cctggatgcc
    58621 gtcaacttca acgcgttttg ccacttcttc cattagttcg agtgtacgcg gatgcagctc
    58681 ttccgtgtct ttgtgcacga acagtgacat cggtacgccc caggtgcgct gacgggagat
    58741 acaccagtca ggacggttag caaccatcga ctcgatacgc gcctggcccc agtccgggat
    58801 ccactgcacg cctttgatct ctttcagtga ctgcgcacgc agacctttct gatccatgct
    58861 gacgaaccac tgcggcgtcg cgcggaagat gatcggcgtt ttgtgacgcc agcagcacgg
    58921 atagctgtgc tgcattttct caacgtgcag cagcgcgcct ttttcctgca gcagcgcaac
    58981 gacgatgtcg ttcgctttga agacgttcac gccatccagc gtcggataag tgcccggcag
    59041 ataagtgccg tccgggccaa ccgggttagc ggtttccagg ccgtatttct gaccgatcac
    59101 atagtcgtcc gggccgtggc caggcgcggt gtgaacggca ccggtaccgg catccagggt
    59161 aacgtgatcg ccgaggattg ccggaacgtc gaagcccata aacggatggg taaagcgcag
    59221 caactcaagc tccgcacctt ttaccgtgcc gagaatggtg taatcggtca cgccgatacg
    59281 ctgcattacg ctttcaacca gatctttcgc cagaatcacg gcctgaccgt cgatctgcac
    59341 cagcgcatag tcgaaatcag gtgcaataga gattgcgcgg ttcgcaggca gagtccacgg
    59401 cgtagtggtc cagatcacca gcgagattgg gccgttaacg ttgcttacgg caaattttgc
    59461 tttcagtgca tcctgatcga ccgcctgaaa agcaacgtcg atggacggag aagttttgtc
    59521 gtaatactca acttccgctt ccgccagcgc agaacggcag tcaacgcacc agtgaactgg
    59581 cttcgcgcct ttgtgcaggt gaccgttgcc gatgattttg cccagcgcgc ggatgatgtt
    59641 ggcttcagtt ttgaagtcca tggtcaggta cgggtgcgac cagtcgccca gcacgcccag
    59701 acggataaag tctttgcgtt gaccgtcaac ctgggtcgcc gcgtattcgc ggcacttggc
    59761 gcggaactcg gcggcggtga atttctcacc cggcttaccg tattcttgct ctactttcag
    59821 ctcgatcggc agaccgtggc agtcccagcc aggcacatac ggcgagtcat aaccggaaag
    59881 ccctttggac ttcacgataa tgtctttcag aatcttgtta accgagtgac caatatgaat
    59941 gctgccattc gcataaggag ggccatcatg cagaatgaag gtttttttgc cttttttagc
    60001 cgcacggatg atgccgtaca gatcatcatc agtccaacgc gccagcattc ccggttcgcg
    60061 cttggcgaga tcgccacgca tcgggaaccc tgtttccggc aaattcaggg ttgatttata
    60121 gtcactcatc agattctcgg ttccgtgttt cggtttgatt acataacagg cttaagccgg
    60181 ttttgttagc ccaaaaaatt cgcgggcggt taattcatca cgcgcaatct gcgctttcag
    60241 ttcgtccagc gacgcaaatc gctgctcatt gcgtattttt ttacgcagca ctacttgtat
    60301 atggcgaccg taaaggtcca ttgcaacatc taacaaatgc acttccagct gctggcgaat
    60361 accggcaacc gttgggcgtg ttccaatgtt tgccacgccg ggtaacggct tttcaccgag
    60421 gcccagcact tctaccgcat aaaccccttt caccggggaa acctgacggc gtagcggtac
    60481 attcgccgtc gggaaaccta tagtgcgccc taattcatca ccgtggacta cacgcccgga
    60541 gatggcaaac gggtgcccca gtaaactttc tgccagagcc agattgtcat ccgccagcgc
    60601 ctgacgcaca gcggtgctgc tgatacgcac gccaccttcg caaaaagttt gcgtactggt
    60661 gatatcgaag ccgtattcca tgccagcttt ctgtaataac aagaaatcgc cttcacgacc
    60721 agcgccaaag cggaaatcat cacctacggc aagaaatttt acgcgcaaat gcttcaccag
    60781 aagatcgctg atgaaatttt gcgcggttaa cgccgcgaaa cgcctgtcga aacgcacgca
    60841 cagcacgtaa tcaacgccac actctgcaag gtaacgcagt ttttcccgca gccgggtcag
    60901 ccgtgccggg gctttatcgg tagcaaacag ttccagtggt tgaggttcaa aaagcatcac
    60961 catcaccggt aagttgcgct tgcgcccttc ttcctgcaag ccctgtaaca gcgcgcgatg
    61021 accgcgatgc acgccgtcga aattaccaat agtcagcaca cacccttctt gcggggcctg
    61081 gctgagatta tgtatgccgc gtatcagctt catgtctggc tcaaaacagt gaaaatcgtc
    61141 cgagtatacc ttgtacagcg gtcaaggtta accggcgatt gagtaccgaa atcagaaaga
    61201 agtggctttt cattgccatg gcgcaaatca cgggaagaaa gtgaccgcct gctgcaattt
    61261 ttatcgcgga aaagctgtat tcacaccccg caagctggta gaatcctgcg ccatcactac
    61321 gtaacgagtg ccggcacatt aacggcgctt atttgcacaa atccattgac aaaagaaggc
    61381 taaaagggca tattcctcgg cctttgaatt gtccatatag aacacatttg ggagttggac
    61441 cttggctaat atcaaatcag ctaagaagcg cgccattcag tctgaaaagg ctcgtaagca
    61501 caacgcaagc cgtcgctcta tgatgcgtac tttcatcaag aaagtatacg cagctatcga
    61561 agctggcgac aaagctgctg cacagaaagc atttaacgaa atgcaaccga tcgtggaccg
    61621 tcaggctgct aaaggtctga tccacaaaaa caaagctgca cgtcataagg ctaacctgac
    61681 tgcacagatc aacaaactgg cttaatcgcc aatttgctga agctttgtga aaaagcccgc
    61741 gcaagcgggt ttttttatgc ctgctgcttt tatgatgcgt gagagaacac actaccggtt
    61801 gccagatagt caaaagatgc tggcttttgc agacatgccg ttacactttc tgaactcttc
    61861 gtggcttaag aatcgtagaa ccatcggctg atacattctg aacaagaata tctactcaat
    61921 ctccagactc ccctacaaag aatgtggata ttgtgataca cattgaggta ttaaacttaa
    61981 gaccactcta tttttgaatt
//
LOCUS       DAZUDJ010000021        61903 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.021, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000021 DAZUDJ010000000
VERSION     DAZUDJ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 61903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61903
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.021"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            125..1510
                     /gene="dcuC"
                     /locus_tag="ACHY1N_001867"
     CDS             125..1510
                     /gene="dcuC"
                     /locus_tag="ACHY1N_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015556 - C4-dicarboxylate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HFS4044190.1"
                     /translation="MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAI
                     MGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLIASILEFLRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELM
                     VPGTAAAVTGK"
     gene            complement(1551..2231)
                     /gene="dpiA"
                     /locus_tag="ACHY1N_001868"
                     /gene_synonym="citB"
     CDS             complement(1551..2231)
                     /gene="dpiA"
                     /locus_tag="ACHY1N_001868"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HFS4044191.1"
                     /translation="MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARM
                     MIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVF
                     DYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGID
                     PLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGR
                     PQRIYHSG"
     gene            complement(2200..3858)
                     /gene="dpiB"
                     /locus_tag="ACHY1N_001869"
     CDS             complement(2200..3858)
                     /gene="dpiB"
                     /locus_tag="ACHY1N_001869"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HFS4044192.1"
                     /translation="MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTAS
                     FEDYLTLHVRDMAMNQAKIIASNDSVISAVKTRDYKRLATIANKLQRDTDFDYVVIGD
                     RHSIRLYHPNPEKIGYPMQFTKQGALEKGESYFITGKGSMGMAMRAKTPIFDDDGKVI
                     GVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIA
                     RVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIAEVVRPA
                     DFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFRSKDEISTLNAQLTQ
                     IKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFAD
                     RQVAGLLFGKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLR
                     SDEGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEHGIGLY
                     LIASYVTRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR"
     gene            4238..5296
                     /gene="citC"
                     /locus_tag="ACHY1N_001870"
     CDS             4238..5296
                     /gene="citC"
                     /locus_tag="ACHY1N_001870"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415151.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008771 - [citrate (pro-3S)-lyase] ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006101 - citrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HFS4044193.1"
                     /translation="MFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTR
                     DEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYE
                     ALFRQCGFSTLTSVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIVMNANPFTNG
                     HRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRGSEYIISR
                     ATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMR
                     YWLETPTISAPPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQ
                     NLLEHSRQDAAARQKTPA"
     gene            5311..5607
                     /gene="citD"
                     /locus_tag="ACHY1N_001871"
     CDS             5311..5607
                     /gene="citD"
                     /locus_tag="ACHY1N_001871"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_component: GO:0009346 - ATP-independent citrate lyase
                     complex [Evidence IEA];
                     GO_function: GO:0008815 - citrate (pro-3S)-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HFS4044194.1"
                     /translation="MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDA
                     IRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ"
     gene            5604..6512
                     /gene="citE"
                     /locus_tag="ACHY1N_001872"
     CDS             5604..6512
                     /gene="citE"
                     /locus_tag="ACHY1N_001872"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415149.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_component: GO:0009346 - ATP-independent citrate lyase
                     complex [Evidence IEA];
                     GO_function: GO:0008815 - citrate (pro-3S)-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006084 - acetyl-CoA metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HFS4044195.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE
                     DSVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNG
                     KMVDGPVIDRARLVLSRAELSGIREE"
     gene            6523..8055
                     /gene="citF"
                     /locus_tag="ACHY1N_001873"
     CDS             6523..8055
                     /gene="citF"
                     /locus_tag="ACHY1N_001873"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009346 - ATP-independent citrate lyase
                     complex [Evidence IEA];
                     GO_function: GO:0008814 - citrate CoA-transferase activity
                     [Evidence IEA];
                     GO_function: GO:0008815 - citrate (pro-3S)-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HFS4044196.1"
                     /translation="MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDR
                     KLCANLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSD
                     CHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNI
                     DVAFLGVPSCDEFGNANGYTGKACCGSLGYAMVDADNAKQVVMLTEELLPYPHNPASI
                     EQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQT
                     GTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVDLHEKGLIRKLLDVQSFDSHAA
                     QSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRG
                     ASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPAR
                     PELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQV
                     KE"
     gene            8059..8610
                     /gene="citX"
                     /locus_tag="ACHY1N_001874"
     CDS             8059..8610
                     /gene="citX"
                     /locus_tag="ACHY1N_001874"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050519 - holo-citrate lyase synthase
                     activity [Evidence IEA];
                     GO_process: GO:0051191 - prosthetic group biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HFS4044197.1"
                     /translation="MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFT
                     VVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPAR
                     DLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRSCLLCEQSAAVCARGKT
                     HQLTDLLNRMEALLNDVDACNVN"
     gene            8585..9463
                     /gene="citG"
                     /locus_tag="ACHY1N_001875"
     CDS             8585..9463
                     /gene="citG"
                     /locus_tag="ACHY1N_001875"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HFS4044198.1"
                     /translation="MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDR
                     INCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDM
                     FRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
                     NSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLL
                     LMAINGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSP
                     GGSADLLILTWFLAQI"
     gene            9514..10977
                     /gene="citT"
                     /locus_tag="ACHY1N_001876"
     CDS             9514..10977
                     /gene="citT"
                     /locus_tag="ACHY1N_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/succinate antiporter CitT"
                     /protein_id="HFS4044199.1"
                     /translation="MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAM
                     IVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSST
                     TVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNT
                     ARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVL
                     GLEFVSKIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDE
                     LKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITR
                     YNSAWNTLVNLATLVVMANGLTRSGFIDWFAGTMSTHLEGFSPNATVIVLVLVFYFAH
                     YLFASLSAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIY
                     GCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN"
     gene            11091..11897
                     /gene="rna"
                     /locus_tag="ACHY1N_001877"
     CDS             11091..11897
                     /gene="rna"
                     /locus_tag="ACHY1N_001877"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HFS4044200.1"
                     /translation="MKAFWRNAALLAVSLLPFSSANALALQAKQYGDFDRYVLALSWQ
                     TGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFG
                     CATRPIPNLPEAHASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACF
                     GFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKL
                     TCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKVGY"
     gene            12127..12537
                     /gene="rnk"
                     /locus_tag="ACHY1N_001878"
     CDS             12127..12537
                     /gene="rnk"
                     /locus_tag="ACHY1N_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HFS4044201.1"
                     /translation="MSRPTIIINDLDAERIDILLEQPAYAGLRIADALNAELDRAQMC
                     SPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLR
                     VGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL"
     gene            12675..12764
                     /gene="yldA"
                     /locus_tag="ACHY1N_001879"
     CDS             12675..12764
                     /gene="yldA"
                     /locus_tag="ACHY1N_001879"
                     /inference="COORDINATES: protein motif:HMM:NF041476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small membrane protein YldA"
                     /protein_id="HFS4044202.1"
                     /translation="MAEAFYILIGFLIMAAIIVMAVLYLENHS"
     gene            complement(12768..14006)
                     /gene="ybdR"
                     /locus_tag="ACHY1N_001880"
                     /pseudo
     CDS             complement(12768..14006)
                     /gene="ybdR"
                     /locus_tag="ACHY1N_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308674.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004024 - alcohol dehydrogenase (NAD+)
                     activity, zinc-dependent [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase"
     gene            14227..14655
                     /gene="uspG"
                     /locus_tag="ACHY1N_001881"
     CDS             14227..14655
                     /gene="uspG"
                     /locus_tag="ACHY1N_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HFS4044203.1"
                     /translation="MYKTIIMPVDVFEMELSDKAVRHAEFLAQDDGVIHLLHVLPGSA
                     SLSLHRFAADVRRFEEHLQHEAEERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAE
                     ELGADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR"
     gene            complement(14776..16341)
                     /gene="ahpF"
                     /locus_tag="ACHY1N_001882"
     CDS             complement(14776..16341)
                     /gene="ahpF"
                     /locus_tag="ACHY1N_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017455864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFS4044204.1"
                     /translation="MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQ
                     NEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIV
                     GSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVH
                     VDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIG
                     LLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKTA"
     gene            complement(16470..17033)
                     /gene="ahpC"
                     /locus_tag="ACHY1N_001883"
     CDS             complement(16470..17033)
                     /gene="ahpC"
                     /locus_tag="ACHY1N_001883"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFS4044205.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            17405..18151
                     /gene="dsbG"
                     /locus_tag="ACHY1N_001884"
     CDS             17405..18151
                     /gene="dsbG"
                     /locus_tag="ACHY1N_001884"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308670.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HFS4044206.1"
                     /translation="MLKKILLLALLPAIAFAEELPSPVKAIEKQGITIIKTFDAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRME
                     QSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
                     ATAAAILASKDPAKTWQEYESSGGKLKLNVPANVSTEQMKVLSANEKLMDDLGANVTP
                     AIYYMSKENTLQQAVGLPDQKTLNIIMGNK"
     gene            18361..19263
                     /gene="ybdO"
                     /locus_tag="ACHY1N_001885"
     CDS             18361..19263
                     /gene="ybdO"
                     /locus_tag="ACHY1N_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4044207.1"
                     /translation="MANLYDLKKFDLNLLVIFECIYQHLSISKAAESLYITPSAVSQS
                     LQRLRAQFNDPLFIRSGKGIAPTTTGLNLHHHLEKNLKGLEQTINIVNKSELKKNFII
                     YGPQLISCSNNSMLIRCLRQDASVEIECHDILMSAENAEELLVHRKADLVITQMPVIS
                     RSVICMPLHTIRNTLICSNKHPRITDNSTYEQIMAEEFTQLISKSAGVDDIQMEIDEK
                     FMNRKISFRGSSLLTIINSIAVTDLLGIVPYELYNSYRDFLNLKEIKLEHPLPSIKLY
                     ISYNKSSLNNLVFSRFIDRLNESF"
     gene            19410..20630
                     /gene="ybdN"
                     /locus_tag="ACHY1N_001886"
     CDS             19410..20630
                     /gene="ybdN"
                     /locus_tag="ACHY1N_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HFS4044208.1"
                     /translation="MSIYKIPLPLNILEAARERITWTLNTLPRVCVSFSGGKDSGLML
                     HLTAELARQMGKKICVLFIDWEAQFSCTINYVQSLRELYTDVIEEFYWVALPLTTQNS
                     LSQFQPEWQCWEPDVEWVRQPPQDAITDPDFFCFYQPGMTFEQFVREFAEWFSQKRPA
                     AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTW
                     YANHQSLCNPLYNLMYQAGVPLRHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVS
                     GVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKTAEHYRNKIAIYLHW
                     YQKKGIEVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKAKNYQRYNERI
                     KGKRQEWGILCNND"
     gene            20603..21232
                     /gene="ybdM"
                     /locus_tag="ACHY1N_001887"
     CDS             20603..21232
                     /gene="ybdM"
                     /locus_tag="ACHY1N_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HFS4044209.1"
                     /translation="MGDTMQQRLTQDLTQFLASLPEDDRIKAINEIRMAIHQVSPFRE
                     EPVDCVLWVKNSQLMPNDYNPNNVAPPEKKLLKKSIEIDGFTQPIVVTHTDKNALEIV
                     DGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
                     RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQYSRAWTVK"
     gene            complement(21233..22393)
                     /gene="ybdL"
                     /locus_tag="ACHY1N_001888"
     CDS             complement(21233..22393)
                     /gene="ybdL"
                     /locus_tag="ACHY1N_001888"
                     /EC_number="2.6.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-oxo-acid transaminase"
                     /protein_id="HFS4044210.1"
                     /translation="MTNNPLIPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDG
                     PHYLQERLAYHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATE
                     ALYAAITALVRNGDEVICFDPSYDSYSPAIALSGGIVKRMALQPPHFRVDWQEFAALL
                     SERTRLVILNTPHNPSATIWQQADFAALWQAIAGHEIFVISDEVYEHINFSQQGHASV
                     LAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLA
                     LADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTLDD
                     VEFCQWLTQEHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL"
     gene            22502..23590
                     /gene="hcxA"
                     /locus_tag="ACHY1N_001889"
     CDS             22502..23590
                     /gene="hcxA"
                     /locus_tag="ACHY1N_001889"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /protein_id="HFS4044211.1"
                     /translation="MPHNPIRVVVGPANYFSHPGSFNYLNDFFTDEQLSRAVWIYGKR
                     AIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTA
                     KALARRLGLPFVAAPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
                     NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALA
                     DQQNQQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRP
                     VESIHYLPVTLTPDTLRAAFEKVESFKA"
     gene            complement(23600..23797)
                     /gene="ybdD"
                     /locus_tag="ACHY1N_001890"
     CDS             complement(23600..23797)
                     /gene="ybdD"
                     /locus_tag="ACHY1N_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HFS4044212.1"
                     /translation="MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(23979..26084)
                     /gene="cstA"
                     /locus_tag="ACHY1N_001891"
     CDS             complement(23979..26084)
                     /gene="cstA"
                     /locus_tag="ACHY1N_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter CstA"
                     /protein_id="HFS4044213.1"
                     /translation="MNKSGKYLVWTVLSVMGAFALGYIALNRGEQINALWIVVASVCI
                     YLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
                     VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAESPTWAPYFDFTGVQLIWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFSITPDTLNQIASEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKVGFLAIANKFQAMIDSG
                     NIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLALFSIKTALAALKEPKPTAKETP
                     YEPMPENVEEIVAQAKGAH"
     gene            complement(26265..26678)
                     /gene="entH"
                     /locus_tag="ACHY1N_001892"
     CDS             complement(26265..26678)
                     /gene="entH"
                     /locus_tag="ACHY1N_001892"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HFS4044214.1"
                     /translation="MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDT
                     RTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVC
                     QPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG"
     gene            complement(26681..27427)
                     /gene="entA"
                     /locus_tag="ACHY1N_001893"
     CDS             complement(26681..27427)
                     /gene="entA"
                     /locus_tag="ACHY1N_001893"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
                     EntA"
                     /protein_id="HFS4044215.1"
                     /translation="MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTAFDQAFAQEQY
                     PFATEVMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAV
                     NVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
                     ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEI
                     ANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(27427..28284)
                     /gene="entB"
                     /locus_tag="ACHY1N_001894"
     CDS             complement(27427..28284)
                     /gene="entB"
                     /locus_tag="ACHY1N_001894"
                     /EC_number="3.3.2.1"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis bifunctional
                     isochorismatase/aryl carrier protein EntB"
                     /protein_id="HFS4044216.1"
                     /translation="MAIPKLQAYALPESHDIPKNKVDWAFEPQRAALLIHDMQDYFVS
                     FWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPVPASKAAL
                     REVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAW
                     WKLLSREVK"
     gene            complement(28298..29908)
                     /gene="entE"
                     /locus_tag="ACHY1N_001895"
     CDS             complement(28298..29908)
                     /gene="entE"
                     /locus_tag="ACHY1N_001895"
                     /EC_number="2.5.1.-"
                     /EC_number="6.2.1.71"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase EntE"
                     /protein_id="HFS4044217.1"
                     /translation="MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVID
                     GERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVL
                     ALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLHNDSGE
                     HNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEIC
                     QFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTLVLAADPSATLCFPLIEKHQVNVT
                     ALVPPAVSLWLQALTEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCLLQQVFGM
                     AEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFR
                     GYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVE
                     CVDSLPLTAVGKVDKKQLRQWLASRASA"
     gene            complement(29918..31093)
                     /gene="entC"
                     /locus_tag="ACHY1N_001896"
     CDS             complement(29918..31093)
                     /gene="entC"
                     /locus_tag="ACHY1N_001896"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008909 - isochorismate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HFS4044218.1"
                     /translation="MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAV
                     NGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEK
                     QTSARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDA
                     AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARR
                     QPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWH
                     LATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWC
                     DSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH"
     gene            31468..32424
                     /gene="fepB"
                     /locus_tag="ACHY1N_001897"
     CDS             31468..32424
                     /gene="fepB"
                     /locus_tag="ACHY1N_001897"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HFS4044219.1"
                     /translation="MRLAPLYRNALLLTGLLLSGIAAVQAADWPRQITDSRGTHTLES
                     QPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLY
                     IGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
                     EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQM
                     LEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIY
                     ANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERLKALF"
     gene            complement(32428..33678)
                     /gene="entS"
                     /locus_tag="ACHY1N_001898"
     CDS             complement(32428..33678)
                     /gene="entS"
                     /locus_tag="ACHY1N_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042931 - enterobactin transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0042930 - enterobactin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HFS4044220.1"
                     /translation="MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFR
                     FLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGAL
                     TSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYT
                     MLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGV
                     LLLLVLVELRRFRQTPPQVTASDS"
     gene            33789..34793
                     /gene="fepD"
                     /locus_tag="ACHY1N_001899"
     CDS             33789..34793
                     /gene="fepD"
                     /locus_tag="ACHY1N_001899"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HFS4044221.1"
                     /translation="MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAF
                     SGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGAS
                     FAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
                     VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALN
                     SLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
                     "
     gene            34790..35782
                     /gene="fepG"
                     /locus_tag="ACHY1N_001900"
     CDS             34790..35782
                     /gene="fepG"
                     /locus_tag="ACHY1N_001900"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HFS4044222.1"
                     /translation="MIYVSRRLLITCLLLVSACVVAGIWGLRSGAVTLETSQVFAALM
                     GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWS
                     GVLVAMVLFGQDLTAIALSAMVGGIVTSLLVWLLSWRNGIDTFRLIIIGIGVRAMLVA
                     FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLE
                     MGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARW
                     GLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            35779..36594
                     /gene="fepC"
                     /locus_tag="ACHY1N_001901"
     CDS             35779..36594
                     /gene="fepC"
                     /locus_tag="ACHY1N_001901"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HFS4044223.1"
                     /translation="MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
                     ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALR
                     EGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTANS"
     gene            complement(36591..37724)
                     /gene="wzz(fepE)"
                     /locus_tag="ACHY1N_001902"
     CDS             complement(36591..37724)
                     /gene="wzz(fepE)"
                     /locus_tag="ACHY1N_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator Wzz(fepE)"
                     /protein_id="HFS4044224.1"
                     /translation="MSSLNIKQGSDAHFPDYPLASPSNNEIDLLNLISVLWRAKKTVM
                     AVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQELEKTFTKLRVLDLDIKIDRTE
                     AFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDELDLHRAIVALSEKMKAVDDNAS
                     KKKDEPSLYTSWTLSFTAPTSEEAQTVLSGYIDYISTLVVKESLENVRNKLEIKTQFE
                     KEKLAQDRIKTKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGAD
                     GIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKAHVNDVNFTPFKYQLSPSLPVKKD
                     GPGKAIIVILSALIGGMVACGGVLLRYAMASRKQDAMMADHLV"
     gene            complement(37940..41821)
                     /gene="entF"
                     /locus_tag="ACHY1N_001903"
     CDS             complement(37940..41821)
                     /gene="entF"
                     /locus_tag="ACHY1N_001903"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0031177 - phosphopantetheine binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin non-ribosomal peptide synthetase
                     EntF"
                     /protein_id="HFS4044225.1"
                     /translation="MSQHLPLVAAQPGIWMAEKLSDLPSAWSVAHYVELTGDVDAPLL
                     ARAVVVGLAQADTLRMRFTEDNGEVWQWVDDALIFELPEIIDLRTNIDPHGTAQALML
                     ADLQQDLRVDSGKPLVFHQLIHVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCTW
                     LRGEPTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLPGR
                     SASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFM
                     RRLGSAALTATGPVLNVLPLGIHIAAQETLPELATRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGDEPLFGPVLNIKVFDYQLDIPDVQAQTHTLATGPVNDLELALFPDVHGDLSI
                     EILANKQRYAEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQINATQV
                     EIPETTLSALVAEQAAKTPDAPALADAHYQFSYREMREQVVALANLLRERGVKPGDSV
                     AVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRF
                     ADVPDLTNLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFF
                     AEYGVTTTHFVPSMLAAFVASLTPQTARQSCATLKQVFCSGEALPADLCREWQQLTGA
                     PLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSG
                     LPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALPLPELKAQAPGRAP
                     KAGSETIIAAAFSSLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQVARQVTPGQVM
                     VASTVAKLATIIDAEEDSTRRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYL
                     DPQWSIIGIQSPRPNGPMQTAANLDEVCEAHLATLLEQQPHGPYYLLGYSLGGTLAQG
                     IAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAAQQGS
                     TSTELFTTIEGNYADAVRLLTTAHSVPFDGKATLFVAERTLQEGMSPERAWSPWIAEL
                     DIYRQDCAHVDIISPGAFEKIGPIIRATLNR"
     gene            complement(41818..42036)
                     /gene="ybdZ"
                     /locus_tag="ACHY1N_001904"
     CDS             complement(41818..42036)
                     /gene="ybdZ"
                     /locus_tag="ACHY1N_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis protein YbdZ"
                     /protein_id="HFS4044226.1"
                     /translation="MAFSNPFDDPQGAFYILRNAQGQFSLWPQQCALPAGWDIVCQPQ
                     SQASCQQWLEVHWRTLTPANFTQLQEAQ"
     gene            complement(42039..43241)
                     /gene="fes"
                     /locus_tag="ACHY1N_001905"
     CDS             complement(42039..43241)
                     /gene="fes"
                     /locus_tag="ACHY1N_001905"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0008849 - enterochelin esterase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HFS4044227.1"
                     /translation="MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYS
                     TIKRVWVYITGVTDHHQNSQPQSMQRIAGTNVWQWTTQLNANWRGSYCFIPTERDDIF
                     SAPSPDRLELREGWRKLLPQAIADPLNPQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
                     PETPAKEIIWKSERLKNSRRVWIFTTGDATAGERPLAVLLDGEFWAQSMPVWPVLTSL
                     THRQQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPLVKAIAPFSDRADRTV
                     VAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGQQEGVLLEQLKAGQVSAEG
                     LRIVLEAGIREPMIMRANQALYAQLHPIKESIFWRQVDGGHDALCWRGGLMQGLIDLW
                     QPLFHDRS"
     gene            43484..45724
                     /gene="fepA"
                     /locus_tag="ACHY1N_001906"
     CDS             43484..45724
                     /gene="fepA"
                     /locus_tag="ACHY1N_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore enterobactin receptor FepA"
                     /protein_id="HFS4044228.1"
                     /translation="MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN
                     LQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE
                     NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
                     GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD
                     KTQADAWDINQGHQSARAGTYVTTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS
                     RQGNLYAGDTQNTNSDAYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHT
                     RNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN
                     QQRMKDLSSNTQALTGANTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTP
                     GLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVG
                     QNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSKNKTTGDRLSII
                     PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS
                     ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYM
                     SVNTHF"
     gene            45764..45862
                     /locus_tag="ACHY1N_001907"
                     /pseudo
     CDS             45764..45862
                     /locus_tag="ACHY1N_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518748.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            45899..46519
                     /gene="entD"
                     /locus_tag="ACHY1N_001908"
     CDS             45899..46519
                     /gene="entD"
                     /locus_tag="ACHY1N_001908"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415115.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009366 - enterobactin synthetase complex
                     [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009239 - enterobactin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HFS4044229.1"
                     /translation="MKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGR
                     KRKAEHLAGRIAAIYALREYGYKCVPAIGELRQPVWPAEVYGSISHCGATALAVVSRQ
                     PIGVDIEEIFSAQTATELTDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKASEI
                     QTDAGFLDYQIISWNKQQVIIHRENEMFAVHWQIKEKIVITLCQHD"
     gene            complement(46641..46793)
                     /gene="hokE"
                     /locus_tag="ACHY1N_001909"
     CDS             complement(46641..46793)
                     /gene="hokE"
                     /locus_tag="ACHY1N_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HFS4044230.1"
                     /translation="MLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            complement(47144..47296)
                     /gene="hokE"
                     /locus_tag="ACHY1N_001910"
     CDS             complement(47144..47296)
                     /gene="hokE"
                     /locus_tag="ACHY1N_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HFS4044231.1"
                     /translation="MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKVVL
                     AYEPKK"
     gene            47265..47534
                     /locus_tag="ACHY1N_001911"
     CDS             47265..47534
                     /locus_tag="ACHY1N_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009008364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044232.1"
                     /translation="MTAARAYFVSMFILPPCEEGTTIQIVQVWVGSPRVDRNIVLGLH
                     LSRPQSKPETGKLQAPAVILPLLSKIAVYLYSKSCFGLLTPHLIN"
     gene            47738..48856
                     /gene="ybdK"
                     /locus_tag="ACHY1N_001912"
     CDS             47738..48856
                     /gene="ybdK"
                     /locus_tag="ACHY1N_001912"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0042398 - cellular modified amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbdK family carboxylate-amine ligase"
                     /protein_id="HFS4044233.1"
                     /translation="MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNE
                     ITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
                     FIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMID
                     SIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKD
                     YLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKMGASSAIEAL
                     HRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD"
     gene            48922..49170
                     /gene="ybdJ"
                     /locus_tag="ACHY1N_001913"
     CDS             48922..49170
                     /gene="ybdJ"
                     /locus_tag="ACHY1N_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1158 domain-containing protein"
                     /protein_id="HFS4044234.1"
                     /translation="MKHPLETLTTAAGILLMAFLSCLLLPAPALGLTLAQKLVTMFHL
                     MDLSQLYTLLFCLWFLVLGAIEYFVLRFIWRRWFSLAD"
     gene            49235..49603
                     /gene="ybdF"
                     /locus_tag="ACHY1N_001914"
     CDS             49235..49603
                     /gene="ybdF"
                     /locus_tag="ACHY1N_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFS4044235.1"
                     /translation="MDKQSLHETAKRLALELPFVELCWPFGPEFDVFKIGGKIFMLSS
                     ELRGVPFINLKSDPQKSLLNQQIYPSIKPGYHMNKKHWISVYPGEEISEALIRDLIND
                     SWNLVVDGLAKRDQKRVRPG"
     gene            49697..50350
                     /gene="nfsB"
                     /locus_tag="ACHY1N_001915"
     CDS             49697..50350
                     /gene="nfsB"
                     /locus_tag="ACHY1N_001915"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HFS4044236.1"
                     /translation="MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAAGNYVFNERKILDASHVVVFCAKTAMDDAWLKLVVDQE
                     DADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
                     AVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV"
     gene            50458..51705
                     /gene="ybdG"
                     /locus_tag="ACHY1N_001916"
     CDS             50458..51705
                     /gene="ybdG"
                     /locus_tag="ACHY1N_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel YbdG"
                     /protein_id="HFS4044237.1"
                     /translation="MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIILHWVV
                     LRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTC
                     AQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRF
                     LDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESILNLRRMTNIGTFRAYLNEY
                     LRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEE
                     FGLRLHQSPTGNDIRSLAGAFKQ"
     gene            complement(51773..53149)
                     /gene="pheP"
                     /locus_tag="ACHY1N_001917"
     CDS             complement(51773..53149)
                     /gene="pheP"
                     /locus_tag="ACHY1N_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HFS4044238.1"
                     /translation="MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLG
                     IGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFL
                     SGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
                     EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVI
                     MFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSN
                     SSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTR
                     VSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRF
                     RAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFV
                     AFKTLRRK"
     gene            complement(53251..56394)
                     /gene="cusA"
                     /locus_tag="ACHY1N_001918"
     CDS             complement(53251..56394)
                     /gene="cusA"
                     /locus_tag="ACHY1N_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter permease
                     subunit CusA"
                     /protein_id="HFS4044239.1"
                     /translation="MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSD
                     VQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTD
                     PYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
                     DWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAG
                     GSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQIGPEMRRGIA
                     ELNGEGEVAGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRA
                     IDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMS
                     LGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPAL
                     FISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGK
                     IPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQIN
                     EGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMV
                     ETTIQLKPQEQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIG
                     IKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTV
                     ADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITL
                     ADVADIKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSV
                     AFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWL
                     LWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAVPSLNNPQTFSEQKLDEA
                     LYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI
                     IPAAYKLMWLHRHRVRK"
     gene            complement(56406..57629)
                     /gene="cusB"
                     /locus_tag="ACHY1N_001919"
     CDS             complement(56406..57629)
                     /gene="cusB"
                     /locus_tag="ACHY1N_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     adaptor subunit CusB"
                     /protein_id="HFS4044240.1"
                     /translation="MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILF
                     WYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRG
                     PLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVE
                     AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVI
                     TAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTL
                     TIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQALID
                     TGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
                     GALERMRSESATHAH"
     gene            complement(57645..57977)
                     /gene="cusF"
                     /locus_tag="ACHY1N_001920"
     CDS             complement(57645..57977)
                     /gene="cusF"
                     /locus_tag="ACHY1N_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     metallochaperone CusF"
                     /protein_id="HFS4044241.1"
                     /translation="MKKALQVAMFSLFTVIGFNAQANEHHHETMSEVQPQVISATGVV
                     KGIDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSL
                     LQDIKVSQ"
     gene            complement(58001..59383)
                     /gene="cusC"
                     /locus_tag="ACHY1N_001921"
     CDS             complement(58001..59383)
                     /gene="cusC"
                     /locus_tag="ACHY1N_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter outer
                     membrane channel CusC"
                     /protein_id="HFS4044242.1"
                     /translation="MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVN
                     AADNYQNAGWRTFFVDNQVKTLISEALVNNRDLRMATLKVQEARAQYRLTDADRYPQL
                     NGEGSGSWSGNLKGNTATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
                     VHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQAR
                     GVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQI
                     LLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNF
                     IPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQIS
                     AQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISL
                     YTALGGGWQQ"
     gene            59540..60223
                     /gene="cusR"
                     /locus_tag="ACHY1N_001922"
     CDS             59540..60223
                     /gene="cusR"
                     /locus_tag="ACHY1N_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper response regulator transcription factor
                     CusR"
                     /protein_id="HFS4044243.1"
                     /translation="MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGD
                     YDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKP
                     FAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
                     FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVG
                     YMLEVPDGQ"
     gene            60213..61661
                     /gene="cusS"
                     /locus_tag="ACHY1N_001923"
     CDS             60213..61661
                     /gene="cusS"
                     /locus_tag="ACHY1N_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) sensor histidine kinase CusS"
                     /protein_id="HFS4044244.1"
                     /translation="MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFA
                     EQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSHGKTVYHSP
                     GAPDIREFTRDAIPDKDARGGEVYLLSGPTIMMPGHGHGHMEHSNWRMINLSVGPLVD
                     GKPIYTLYIALSIDFHLHYINDLMNKLIMTASIISILIVFIVLLAVHKGHAPIRSVSR
                     QIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP
                     ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKK
                     MLNLADEVGKVFDFFEALAEDRGVELRFVGDECQVAGDPLMLRRALSNLLSNALRYTP
                     PGEAIVVRCQTVDHQVQVTVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLA
                     IVKSIVVAHKGTVAVTSDARGTRFVIMLPERE"
BASE COUNT        14857 a        16774 c        15586 g        14686 t
ORIGIN      
        1 atgtcttaat ggcagttttt cttgatttta atcagcattc atcgccaatt tattgggcat
       61 attttttcct taagctttag gaatttttta ttatttactt tggggcctgg agacaggaaa
      121 aattatgctg acattcattg aactccttat tggggttgtg gttattgtgg gtgtagctcg
      181 ctacatcatt aaagggtatt ccgccactgg tgtgttattt gtcggtggcc tgttattgct
      241 gattatcagt gccattatgg ggcacaaagt gttaccgtcc agccaggctt caacaggcta
      301 cagcgccacg gatatcgttg aatacgttaa aatattacta atgagccgcg gcggcgacct
      361 cggcatgatg attatgatgc tgtgtggatt tgccgcttac atgacccata tcggcgcgaa
      421 tgatatggtg gtcaagctgg cgtcaaaacc attgcagtat attaactccc cttacctgct
      481 gatgattgcc gcctattttg tcgcctgtct gatgtctctg gccgtctctt ccgcaaccgg
      541 tctgggtgtt ttgctgatgg caaccctatt tccggtgatg gtaaacgttg gtatcagtcg
      601 tggcgcagct gctgccattt gtgcctcccc ggcggcgatt attctcgcac cgacttcagg
      661 ggatgtggtg ctggcggcgc aagcttccga aatgtcgctg attgacttcg ccttcaaaac
      721 gacgctgcct atctcaattg ctgcaattat cggcatggcg atcgcccact tcttctggca
      781 acgttatctg gataaaaaag agcacatctc tcatgaaatg ttagatgtca gtgaaatcac
      841 caccactgct cctgcgtttt atgccatttt gccgttcacg ccgatcatcg gtgtactgat
      901 ttttgacggt aaatggggtc cgcaattaca catcatcact attctggtga tttgtatgct
      961 gattgcctcc attctggagt tcctccgcag ctttaatacc cagaaagttt tctctggtct
     1021 ggaagtggct tatcgcggaa tggcagatgc gtttgctaac gtggtgatgc tgctggttgc
     1081 cgctggggta ttcgctcagg ggcttagcac catcggcttt attcaaagtc tgatttctat
     1141 cgctacctcg tttggttcgg cgagtatcat cctgatgctg gtattggtga ttctgaccat
     1201 gctggcggca gtcacgaccg gttcaggcaa tgcgccgttt tatgcgtttg ttgagatgat
     1261 cccgaaactg gcgcactctt ccggcattaa cccggcgtat ttgactatcc cgatgctgca
     1321 ggcgtcaaac ctgggccgta ccctttcgcc cgtttctggc gtagtcgttg cggttgccgg
     1381 gatggcgaag atctcgccgt ttgaagtcgt aaaacgcacc tcggtaccgg tgcttgttgg
     1441 tttggtgatt gttatcgttg ctacagagct gatggtgcca ggaacggcag cagcggtcac
     1501 aggcaagtaa atagtaatgc cggaggcaag tttcctccgg ctttatcatg tcacccactg
     1561 tggtatatgc gttgcggtct gccaactttg ccgtgaacaa tttcagcaat aatcagatgg
     1621 cggctggcgc aatattcaag ataacgcctg gcagtggtgc gactgatggt cagtgcctgc
     1681 gccaccgttt ctgccgtatg ttgcacacca ggctctttaa acagttttcg caccgcgttt
     1741 agcgtcaagg gatcaatgcc ggtcggcagt tcgtctttag gttcaccgcg agcataggca
     1801 ttaaacatct catcaatttg cttctggctg gcgctatcaa tactttccag catatgttta
     1861 cgctggcgga aacgggttag cgtttgcccc agccgttcat aggcaatggg cttaatgaga
     1921 taatcaaata caccacaacg tacggcttca gacaccgttt ccatatcgct ggctgcagtg
     1981 gtaaacacca cgtcgccggg ataatgcgcc tgcaccagtt catgcaataa attaatccct
     2041 ctgccgtcag gaagatagtt atcgagcaag attagccccg gcttaaaacg ctcgatcatc
     2101 attcgggcct gcgccaggtt tcccgccagt aatatctgac tgaatccggg aatgtgacga
     2161 atatattccg catgcatctc tgccagcggc gtttcgtcct caacgatcaa tagggttaat
     2221 ggagctgtca ttaggtttca ctttcggaat atagattgaa aacaaggtac cgcagggatc
     2281 attatcttcg agagtgataa caccaccgca gcgcgttacg tagctggcaa tcaagtacaa
     2341 cccaatgcca tgttcaccgg gctcgtcagc acgcgtactg accccctgct caaatatttt
     2401 gtctcgtaga gactctggaa cgccgcagcc ctgatcggcg acttcaatca ccacatcatc
     2461 gccttcatcg ctgaggaata attcaacgat cttgtttcct tcatcgctac gcaggctggc
     2521 ttcgaaggcg ttatcaagta aattgcccac aatggctgca aactcggtgc tatccagtcc
     2581 tggcggcagt tgcgaaagct ggctaccggg gacaatgatc atttttagcc ccagttcccg
     2641 ggcgcgctgc actttaccaa aaagcagccc cgccacctgg cgatcggcaa acgcctcacg
     2701 caggctgtca ataagctgtt gctgggcctg agactccccc tgcaccatcg ccagcacgcg
     2761 atcatactct ttcatctgca acagaccatt gagcgtcgac atccaattga gatgctcgtg
     2821 tcgcaatgta cgaaggctct cgacgtattg ttttatttgc gtcagttgcg cattgagggt
     2881 ggaaatttcg tctttactac gaaagctgat aatggccccc agcaaatcat cacctgaacg
     2941 aatagcttcc cgattggcaa taacgctcag accgttaaag ttagccacca catcctgacg
     3001 tttttcatca atctgttcgg taaagaaatc ggcgggcctg accacttcag caatgggttt
     3061 acccaaccat tgccgtccgg gagagctcag ccccagcatc tttcttgcgt tacgattgat
     3121 ggcggtaatg taaccatgcg gatccaccgc aatcagccct tcataaaccg aactaaacag
     3181 cgcctcttgc tgacggacca cgcgtgcgat ttgctttggc tccatgccca tcatttgccg
     3241 acggatatgc gctgccagga accacgacag caacatcaga atccctaaca gcacgacaaa
     3301 cacgcctgcc atcggtaata aaaactcagc ccgccagcta tcgattttac tcaccaggta
     3361 gccaatcgac accacgccga tgacttttcc atcgtcatca aagattggcg ttttggcgcg
     3421 catcgccatc cccattgacc ctttcccggt aatgaagtag ctctcccctt tctccagcgc
     3481 gccctgtttg gtgaactgca taggataacc aattttctcc ggattaggat ggtaaaggcg
     3541 gatcgagtgc cggtccccaa tcaccacata atcaaaatcg gtatctcttt gtaatttgtt
     3601 agcgatggtc gccagccgtt tgtagtcacg cgttttcacc gcagagatga cactgtcatt
     3661 ggaggcaata attttcgcct gattcattgc catgtcgcgt acatgaagcg ttaaatagtc
     3721 ctcaaaactg gccgtaaaat attgcgccag ggctgcaatg acaaatattg agaacaccag
     3781 aatcagcaaa aagatacgca gcggaaatgc cagtctttgg aaaaatgcaa actgtttatt
     3841 ctcgttaagc tgcaacattg ttttccttgc gggttgtccc gagcctcttt gacggatgta
     3901 attaaaatgt tgaatcaaaa tacatagata ttaattatga tcgtggcaaa ttttattcat
     3961 taaatcaatt aaatcactta aacctgctgg tcatttcgta attacattaa ttaaaaaact
     4021 taaaaccatt aaataaataa aaaaccacta actctatgtg aaataaatca aaatttcacg
     4081 ccgaaatact ccttaggatg tatagcgaaa ggagaaaaag atatacctcg atcacccccc
     4141 tttctcccaa gtgaaaataa aaggttatca gtttgcaaca ttgaacaaca ttcgttgcaa
     4201 atcgataaca acatgcacct tcaggatact atttattatg ttcggcaatg atattttcac
     4261 ccgcgtaaaa cgttcagaaa ataaaaaaat ggcggaaatc gcccaattcc tgcatgaaaa
     4321 tgatttgagc gttgacacca cagtcgaagt atttattacc gtaacccgcg atgaaaagct
     4381 tatcgcgtgc ggtggaattg ccggaaatat tattaaatgc gttgctatca gtgaatccgt
     4441 tcgcggtgaa ggactggcgc tgacattagc cactgaactg ataaacctcg cctatgagcg
     4501 gcacagcacg catctgttta tttataccaa aaccgaatac gaggcgctgt tccgccagtg
     4561 cggtttttcc acgctgacca gcgtacccgg cgtgatggtg ctgatggaaa acagcgccac
     4621 gcggctgaaa cgctatgccg aatcgctgaa aaaatttcgt catccaggga acaagattgg
     4681 ctgcattgtg atgaacgcca atcccttcac gaatggtcac cgttatctga ttcaacaagc
     4741 tgcggcacag tgcgactggt tgcatctgtt tttagtcaaa gaagattctt cacgcttccc
     4801 ctatgaagac cggttggatc tggtgttaaa aggcaccgcc gatattccac gcctgactgt
     4861 gcatcgcggc tccgaataca tcatctcccg cgctacgttc ccttgctact tcattaaaga
     4921 acagagcgtc attaaccatt gttacaccga aattgatctg aagattttcc gtcagtacct
     4981 cgctcccgcg ctgggtgtaa ctcaccgctt tgtcggtact gaaccctttt gtcgcgttac
     5041 cgcccagtac aaccaggata tgcgctactg gctggaaacg ccgactatct ccgcaccgcc
     5101 catcgaactg gttgaaattg agcggctgcg ttaccaggag atgccgatat ccgcttcccg
     5161 ggtacgtcaa ctgctggcga aaaacgatct cacggctatc gcgccgctgg tccctgcagt
     5221 cacgctgcat tatttgcaga acctgcttga gcactcccgc caggacgcgg cagctcgtca
     5281 aaagaccccc gcatgagaaa caggtgaaaa atgaaaataa accagcccgc cgttgcaggc
     5341 acccttgagt ctggggatgt gatgatacgc atcgccccac tcgatacgca ggatatcgac
     5401 ctgcaaatca atagcagcgt tgagaaacag tttggcgatg caattcgcac caccattctg
     5461 gacgttctcg cccgctacaa cgtgcgcggc gtacagctga atgtcgatga caaaggcgca
     5521 ctggactgca ttttacgtgc acgactggaa gccctgctgg cacgcgccag cggtatcccg
     5581 gctctgccat gggaggattg ccaatgattt ccgcttcgct gcaacaacgt aaaactcgca
     5641 cccgccgcag catgttgttt gtgcctggtg ccaatgccgc gatggtcagc aactccttca
     5701 tctacccggc tgatgccctg atgtttgacc tcgaagactc cgtggcatta cgtgaaaaag
     5761 acaccgcccg ccgcatggtt tatcacgcgc tgcaacatcc gctgtatcgc gatattgaaa
     5821 ccattgtgcg tgtcaacgcg ctggattccg aatggggtgt taacgacctg gaagccgtcg
     5881 ttcgcggtgg tgcggacgtt gtgcgtctgc cgaaaaccga taccgctcag gatgttctgg
     5941 atattgaaaa agagatcctg cgtatcgaaa aagcctgtgg tcgtgaaccc ggcagcaccg
     6001 gcctgctggc ggcgattgaa tctccgctgg gcattacccg cgcagtggaa atcgctcacg
     6061 cttccgagcg tttgatcggt atcgccctcg gtgcagaaga ctatgtgcgc aacctgcgta
     6121 cagaacgctc cccggaagga actgaactgc tgttcgcacg ctgttccatt ttgcaggccg
     6181 cgcgctctgc gggtattcag gcgttcgata ccgtctattc cgacgctaac aacgaagccg
     6241 gattcctgca agaagccgcc cacatcaaac agctgggctt tgacggcaaa tcgctgatca
     6301 acccgcgtca gattgatctg ttgcacaacc tctacgcacc aacccagaaa gaagtggatc
     6361 acgcccgccg cgtcgtagaa gccgctgaag ccgccgctcg cgaaggcctc ggcgtggttt
     6421 ccctgaacgg caagatggtg gacggtccgg ttatcgatcg cgcccgtctg gtgctctctc
     6481 gtgcagaact ttccggcatc cgcgaagaat aaggcaatca aaatgacgca gaaaattgaa
     6541 caatctcaac gacaagaacg ggtagcggcc tggaatcgtc gcgctgaatg cgatcttgcc
     6601 gctttccaga actcgccaaa gcaaacctac caggctgaaa aagcgcgcga tcgcaaactg
     6661 tgcgccaacc tggaagaagc gattcgtcgc tctggtttac aggacggcat gacggtttcc
     6721 ttccatcacg ctttccgtgg cggtgacctg accgtcaata tggtgatgga cgtcatcgcg
     6781 aagatgggct ttaaaaacct gaccctggcg tccagctccc tgagtgattg ccatgcgccg
     6841 ttggtagaac acattcgcca gggcgtggtt acccgcattt atacctccgg cctgcgcggt
     6901 ccactggcgg aagaaatctc ccgcggtctg ctggcggaac cggtgcagat ccactctcac
     6961 ggcggtcgtg tgcatctggt acagagcggc gaactgaata tcgacgtggc tttcctcggc
     7021 gtcccgtcct gtgatgaatt cggtaatgcc aacggctaca ccggtaaagc ctgctgcggc
     7081 tccctcggct atgcaatggt tgatgccgac aacgcaaaac aggttgtgat gcttaccgaa
     7141 gaactgctgc cttatccgca taatccggca agcattgagc aagatcaggt tgatttaatc
     7201 gtcaaagttg atcgcgttgg cgatgctgca aaaatcggcg ctggtgctac ccgtatgacc
     7261 actaacccgc gcgaactgct tattgcccgt agcgctgcgg atgtgattgt caactcaggc
     7321 tacttcaaag aaggtttctc catgcaaacc ggcaccggcg gcgcatcgct ggcggtaacc
     7381 cgtttcctgg aagacaaaat gcgtagccgc gatattcgcg ccgacttcgc cctcggtggt
     7441 attaccgcga cgatggttga tctgcacgaa aaaggtctga tccgcaaact gctggatgta
     7501 cagagctttg acagccacgc tgcgcaatcg ctggcccgta accccaatca catcgaaatc
     7561 agcgccaacc agtacgctaa ctggggttcg aaaggtgcat cggttgatcg tctcgacgtg
     7621 gtggtactga gcgcgctgga aattgacacc cagttcaacg ttaacgtgct gaccggctct
     7681 gacggcgtac tgcgtggtgc ttccggtggt cactgcgata ccgcgattgc ctctgcgctt
     7741 tccatcatcg tcgcgccgct ggtacgcggt cgtattccga ctctggtgga taacgtgctg
     7801 acctgcatca ccccgggctc cagtgtcgat attctggtca cagaccacgg tatcgcagtt
     7861 aacccggcac gtccggagct ggcagaacgt ctgcaggaag cgggcattaa agtggtttcc
     7921 attgagtggc tgcgtgaacg tgcgcgtctg ctgaccggtg aaccacagcc gattgaattc
     7981 accgaccgcg tcgttgccgt tgtgcgttac cgcgatggct cggtgatcga tgttgtacat
     8041 caggtgaagg aataagccat gcacctgctt cctgaactcg ccagccacca tgcggtgtca
     8101 attcccgagc tgctcgtcag ccgggatgaa aggcaagcac ggcaacacgt ctggctcaag
     8161 cgccatcctg ttccactggt ctcctttacc gtggttgcgc ctgggccgat taaagacagt
     8221 gaggtcacac gccgaatttt taatcatggc gtgacagcct tgcgtgcctt agccgcaaaa
     8281 cagggctggc aaattcagga gcaggctgca ctggtttccg ccagcgggcc ggagggtatg
     8341 ttgagcattg ccgccccggc tcgcgacctc aagctcgcca ccattgagct tgaacatagt
     8401 catcctctcg ggcggttatg ggatatcgat gtcctgacgc ccgaaggcga aattctctcc
     8461 cgccgcgact attcactgcc gcctcgcagc tgcctgttgt gcgagcaaag cgcagccgtc
     8521 tgcgcgcgtg gaaaaaccca tcaactgacc gatttactca accgcatgga ggcactgctg
     8581 aacgatgtcg atgcctgcaa cgtcaactaa aaccacaaag cttgcgacgt cattaatcga
     8641 tgagtacgcc ctgctgggct ggcgcgccat gctgactgaa gtcaatctgt caccgaaacc
     8701 aggcctcgtg gatcggatta actgcggtgc gcataaagat atggcgctgg aagatttcca
     8761 ccgcagcgcg ctggcgattc agggctggct accccgtttc attgaatttg gtgcctgtag
     8821 tgcggaaatg gcaccagaag cggtactcca cggattacgc ccaattggta tggcttgcga
     8881 aggtgatatg ttccgcgcca ctgcgggcgt aaacacgcat aaaggcagca ttttttcttt
     8941 agggctgcta tgtgcggcaa ttggccgttt gcttcagctc aaccagccgg taacgccaac
     9001 aaccgtttgt tctacggcgg caagtttctg ccgtggtctg accgatcgcg aactgcgtac
     9061 caataattca caactgacgg caggtcaacg gttgtaccag cagcttggcc ttaccggcgc
     9121 acgcggtgaa gccgaagcgg gttatccact ggtgatcaac cacgccttgc cgcattacct
     9181 cactctgctg gatcaggggt tagatcctga actggcattg ctcgatacct tgctcctact
     9241 gatggcgatc aacggcgata ccaacgttgc ttcgcgcggt ggcgaggggg gcctgcgctg
     9301 gctacagcgc gaggcgcaaa cattattgca aaaagggggc attcgaaccc ccgccgatct
     9361 cgattatctc cggcagttcg acagggagtg tatcgaacga aatctcagtc caggcggcag
     9421 tgccgacctg ctgatcctta cctggttttt agcacagatt taattattta agcacttgat
     9481 aaatttgaaa atattaattt tcggagaacc cgtatgtctt tagcaaaaga taatatatgg
     9541 aaactattgg ccccactggt ggtgatgggt gtcatgtttc ttatccctgt ccccgacggt
     9601 atgccaccac aggcatggca ttacttcgct gtgtttgtgg caatgattgt cggcatgatc
     9661 ctcgagccaa ttccggcaac agcgatcagt tttattgcgg ttactatttg cgttattggc
     9721 agtaattacc tgctctttga tgccaaagaa ttagctgacc cagcgtttaa tgcgcaaaaa
     9781 caggcgctga aatggggtct ggctggtttt tccagcacca cggtatggct ggtatttggc
     9841 gcatttattt ttgcattagg gtatgaagtt tccgggttag gtcgtcgcat tgcccttttc
     9901 ctggtgaaat tcatgggcaa acgcacgctg acgttgggtt atgcgattgt cattatcgac
     9961 attctgctgg caccgtttac accgtccaac accgcgcgta ccgggggtac ggtttttccg
    10021 gtcattaaaa acctgccgcc gttgtttaaa tcattcccca acgatccgtc cgcgcgtcgt
    10081 attggcggct atttgatgtg gatgatggtc attagtacca gtctgagttc gtccatgttt
    10141 gtcaccggtg cggcaccaaa cgtgctgggt ctggagttcg tcagcaaaat tgccggtatc
    10201 cagattagct ggttgcagtg gttcctctgc ttcctgccgg ttggggttat cttgcttatc
    10261 attgcgccgt ggctttccta cgtgctgtac aaaccggaaa tcacacacag tgaagaagtg
    10321 gcaacctggg cgggtgatga actgaaaacc atgggtgcgc tgacacgcag agagtggaca
    10381 ctgattggcc ttgtattgct cagcttaggt ttgtgggttt ttggcagtga agtcattaat
    10441 gctactgcag ttggtctgct ggcagtttcg ctaatgctgg ccctgcacgt tgtgccttgg
    10501 aaagatatta cccgctataa cagcgcatgg aacacgctgg tcaacctggc aactctggtt
    10561 gtgatggcta acggcctgac tcgttctggc tttattgact ggttcgccgg taccatgagt
    10621 acgcacctgg aaggattctc accaaacgca acggtgattg tactggttct ggtgttctac
    10681 tttgcacact acctgtttgc cagcctgtct gcgcacaccg caaccatgct gccggttatt
    10741 ctggccgtcg gtaaaggtat tccgggcgta ccaatggaac aactgtgtat cctgctggtg
    10801 ctgtctatcg gtatcatggg ctgtctgacg ccgtatgcaa ccggtcctgg ggtgattatt
    10861 tacggctgtg gctatgtgaa atcaaaagat tactggcgtc ttggcgcaat cttcggggtg
    10921 atttacatct ctatgttgct gttggttggc tggccgattc tcgccatgtg gaactaatac
    10981 gttcgccaaa cgctgaataa atcatcacgc ccgccaggta agcccacctg gcgggctttt
    11041 ttatgattta atagatagta ttcagtgtat gtatgagttc cacacccatt atgaaagcat
    11101 tctggcgtaa cgccgcgttg ctcgcggttt ctctgcttcc cttctcttct gccaacgcct
    11161 tagcgttgca ggcaaaacag tatggcgatt ttgatcgcta tgtcctggcc ctctcctggc
    11221 aaaccggatt ttgccagagt caacacgatc gaaatcgtaa cgaacgagat gaatgtcgcc
    11281 tgcaaaccga aacgaccaac aaagctgatt ttctgaccgt acatggtctg tggccaggat
    11341 tgcctaaatc ggttgctgcc cgtggtgttg atgaacgccg ctggatgcgc ttcggttgcg
    11401 ctactcgccc aatcccgaat ctaccagaag cgcacgccag ccggatgtgt tcatcgccgg
    11461 aaaccggatt atcactggaa acggccgcta aactaagtga agtcatgcca ggagctggcg
    11521 gacgttcctg cctggaacgc tacgaatatg ccaaacacgg tgcctgcttt ggttttgatc
    11581 cggacgcata cttcggtacg atggtacgcc tgaatcaaga aattaaagag agcgaagccg
    11641 gaaaattcct tgcggataat tacggtaaaa cagtgagccg ccgtgacttt gacgccgcct
    11701 ttgccaaaag ctggggaaaa gagaacgtga aagcagttaa gctaacgtgc cagggtaacc
    11761 ctgcgtattt gactgaaatt cagatctcga tcaaagctga cgccatcaac gctccgcttt
    11821 ctgcaaactc attcttgcca caaccacacc caggcaactg tggcaaaacc tttgtgattg
    11881 ataaagtggg ttattaatca tctgatttac aaaacacgct aattcgtctt ccataaaccg
    11941 tgacgattaa gaattataca taatgcgctg cattgaggaa ttccctgaat gtgacgcaaa
    12001 tcacttcaaa gagtgagcaa cagtcagtat catcatgtga gttaaaccct cgccgcctga
    12061 cggtgagggt tttcttttgg gtatgtttat ctgcgacact cgcagtaccg acgacatgga
    12121 gtaaaaatgt ccagaccaac tatcatcatt aacgacctgg atgccgaacg catcgatatt
    12181 ctgctggagc aacccgccta tgctggtttg cgaatcgccg acgcgttaaa cgcagagttg
    12241 gatcgcgccc aaatgtgttc gccagaagag atgccacacg acgtggtgac aatgaacagc
    12301 cgggttaaat tccgcaatct tagcgatggc gaagtgcgtg tgcgcacgct ggtgtatccg
    12361 gcaaaaatga ccgatagcaa tactcagctt tccgttatgg ctccggtagg tgccgcactg
    12421 ctggggctgc gcgttggcga ttccattcac tgggaacttc cgggcggcgt tgcaacccac
    12481 cttgaagtgc tggaactcga ataccagcca gaagctgctg gcgactacct gctttaatcc
    12541 catctgcaca agcgataact cgctttgccc agaggatgca ctcgcatcct ctttacgcaa
    12601 aatcagcaat ttttcctggt tctcactgtt cacttttgct gcaaaattat tccgtttcgt
    12661 ttgtgggaat aaccatggca gaagcatttt acatcctgat aggatttctg attatggcgg
    12721 cgattatcgt catggctgtc ctttacctcg aaaaccactc ctgacgatca tattgttccc
    12781 cccggcatcg cattcaccag acctgaaacc gccttctgcg ccgcctctgc gctttgtgca
    12841 ccgggtacca gaatcacctt acggcactcc tcttcacgtt tttcgaaaat ctcatatccc
    12901 cgggcggcct cttaaaacgg catatagtgg gtaacaattt cttctggttt cagtaatcct
    12961 ttctcaatta acggtaataa ttctcccagc catgcgtgaa cgtgggtctg tcccatttta
    13021 aacgtcaacc ctttatcaaa ggcgtcgcca aacaggaaac cgtgaataaa tccagcgtag
    13081 acgcccggta cgctaacaat gccgccacgc ctgaccgccg caatacactg gcgcaacgct
    13141 ttaccgctgc tgccctccag tttcaggtta gtcagcaccg tttccgtggt gctgcctttc
    13201 gcttcaaaac cgacggcgtc tattactgca tccacgcccc ggtgacctgc cgtttgttca
    13261 ataattgact gtgccggatc gctatcttca tcgaaattaa tcgggatcgc gccgtagcgg
    13321 tcagcggcga aacgcaagcg gtagggatga tgatcaacaa caaaaatctg ttccgcaccg
    13381 agcaaccgtg cacaggcgat tgtcaacaat cccactggac cggcaccata gactgcaacg
    13441 cttgaacctt gttggatctg cgcatttttt gctgcctgcc atgccgttgg cagaatatca
    13501 gaaaggaaaa gggctttatc atctgaaagc aaaggcggta ctttaaacgg ccccacattc
    13561 cctttaggga cgcggacata ttccgcctgt ccaccaggaa cgccaccata caggtgacta
    13621 taaccaaaca atgccgcggg agctggtatc tgttttttat tgagcgcagc gcctttaccc
    13681 gcattggtat tttcgcaggc ggcatattgc tgcattcgac agaaaaaaca gtcgccacaa
    13741 gcaatgacaa acggaattac cacccggtcg cctttttgca aattttttac gtcctttccg
    13801 gtttcaacga cttcccccat aaattcatga ccaaaaatat cgccatgttt aacctggggt
    13861 attttgcctc gataaagatg gaggtcagag ccacagatcg ccgttgccgt aatacgcaga
    13921 ataatatcat ctgcctgttc aatgcccgga tcgggaacat tttctacctg aacgtgatgt
    13981 gggccgtgat aagtcaatgc tttcatgcaa cctccagaga cagttcaaaa aagagtcagt
    14041 ctttaagggt agctatcaca gcgggaaaac gggcggtacc gcaggttttg ggagaattct
    14101 tggtgttcag tgagaatata ttaatcacag aaaccgttcg taaggaaaaa gaaccagaca
    14161 aatatcaggg ataaatatta taatcatggc gaatgatttg ttcatgatta acagggagaa
    14221 agggttatgt ataagacaat cattatgcca gttgatgtat ttgaaatgga attgagcgac
    14281 aaagctgttc gccacgctga attcctcgcc caggatgacg gagttattca tctacttcac
    14341 gtactacccg ggtcagccag cctgagcctg caccgttttg ccgctgatgt gcgtcgtttt
    14401 gaagagcatc tgcaacatga agcagaagaa cgtctgcaaa cgatggtcag ccacttcacc
    14461 atcgatcctt cccgcattaa acaacatgtc cgttttggta gcgtgcggga tgaagtcaat
    14521 gagttggcag aagaactggg ggctgatgtt gtagttattg gttctcgcaa cccatcgatt
    14581 tcgacccatc tgttaggttc taacgcctcg agcgtgatcc gccatgccaa tctgccggtg
    14641 ctggttgtgc gttaattgcc agaataaata tcccgccctg cccggagcca tcccggcagg
    14701 gctttttaat gccataaaaa agccgccagg tttgaccccg gcggctaagc aattgcaggt
    14761 gaatcttact tcttcttatg cagttttggt gcgaatcagg tagtcaaaag cactcagaga
    14821 ggctttggca ccttcgccag tggcgatgat gatctgcttg tacggaaccg tcgtacagtc
    14881 acccgctgcg aatacgcctt tgacgttggt ttcgcatttc gcatcaatga taatctcacc
    14941 catgcggtta cgttcgactg cgccttccag ccagttggtg ttcggcagca gaccaatctg
    15001 gacgaaaata ccggccagtt cgatgttgtg aatatcgccg ctgacacgat ctcgatattc
    15061 cagaccaacg actttgctgc cgtcgccttt cacttccgtg gtttgcgcat tcagaataat
    15121 gtcgacgttt ttcaggctgc gcagtttgtc ctgcagcacc tggtcggctt tcatttctgg
    15181 cgcaaattcc agcagagtta cgtgctcaac gatacccgcc aggtcgattg ccgcttccac
    15241 gccggagtta ccgccgccga taaccgctac gcgtttgcct ttaaacagcg ggccgtcgca
    15301 gtgcgggcag taggtcacgc ctttggtgcg atactgatct tcgcccggaa cgttcatgtt
    15361 gcgccatttt gcaccggtcg ccacgataat gctgcgtgct ttcagtaccg cgccagaagc
    15421 tgtttcaatc tggtgtagac caccttcaac cgctgccggg atcagtttgc tggcgctctg
    15481 gctgtcgatc acatcaacgt cgtattcatc aacgtgaact ttcagtgcgc ctgccagctt
    15541 ctgcccttca gtcttcggta cagaaatgta gttttcgata tcaacggtat cgaggatctg
    15601 accaccaaaa cgttcgccca tcagaccggt acggatgcct ttacgtgcgg agtaaattgc
    15661 tgccgctgca cccgccgggc cggaaccgac gattaatacg tcataagcat cacgcttgtt
    15721 cagctcttct gccgcacgtt tttccgcgcc agtatcaatt ttggcaacga tttcagtcaa
    15781 cgtcatgcgg ccctgaccaa actctttccc gtttacgaac actgccggaa cgcccatcac
    15841 gttgcgatcg gtgatttcgt tctggaaggt gccgccgtca attgcagtgt gcttgatgcg
    15901 cgggttcagt acgctcatca ggttcagcgc ctgcaccacg tccgggcagt tgtggcaaga
    15961 gagcgagtaa taggtttcga attcaaaatc accgtcaata tggcgaatct gctccagcag
    16021 agactgcgct tctttcgacg gatgaccacc ggtccacagc aacgccagta ccagcgaggt
    16081 gaactcgtgg cccagcgggg agcctgcaaa acgtggcccc tggttggaac ctgggttggt
    16141 gatcaggaaa gacggcttac gcaccggcaa gctgttatct tctttaaagg tgactttgtc
    16201 tgacagttct gcgatttcag ccaacagttc cttgatttct gccgatttag cgctgtcatc
    16261 cagcgtggca attaactcaa caggcttggt caatttctca aggtaagcct tgagttgagt
    16321 tttcatattt gtgtcgagca tgtttatctc ctgggcttta aacatcatca tgcaagcggc
    16381 ctctgcggct acctggatgc agcttgcatc atggtgcggg gaagaaaatc gggtgccgca
    16441 gcacccgatt aattacgcga ttgcggaact tagattttac caaccaggtc cagagacgga
    16501 gccagagttg cttcaccttc tttccattta gccgggcaaa cttcacctgg gtgagaagct
    16561 acgtactgtg ctgctttgat tttacgcagc aggtcagacg cgtcacggcc aatgccttca
    16621 gcggtaactt cgattgcctg gatgataccc tgcgggtcaa caacgaaggt cgcacggtca
    16681 gccagacctt catcttcacg catgttgtcg aagttacggg tcagggcgcc agtcgggtcg
    16741 ccgatcatcg catatttgat tttagcgatg gtttcagagc tgctgtgcca tgctttgtgg
    16801 gtgaagtgag tatcggtaga tactgcgtat acgtctacgc ccagtttctg cagttcttcg
    16861 tagtggtcag caacgtcacc cagttcggtc gggcatacga aagtaaagtc agccgggtag
    16921 aagaagaaga cgctccagcg gccttcggta tctttttcgg tgatttcgat gaattcgccg
    16981 tttttgaatg cctggttttt aaaaggttta attttggtgt taatcaagga catctatact
    17041 tcctccgtgt tttcgatgag atgtaaggta accaattttt gccgattcgg ctaatgcgtt
    17101 tccattatca aatcgataag ttttacctta caaccttcgt aagacaactt tgtgaacttt
    17161 gcaccgccag cggcgataaa aagtaaaatg gccccctttc caggtgaccg tgtaatctga
    17221 actacccttt ggtatcttca gcgcctgcct gcaggctgag gtgttgccct tacaaatgca
    17281 acaacgacat ggattacaac accctcataa acaaagggca atcacctgat ctaagctctt
    17341 acctatgaca gtgataggtt atgcctttta ctcgactttt gcactgactg aaaaggacaa
    17401 attaatgtta aaaaagatac ttttactggc tctgcttcct gcaatcgcct tcgcagagga
    17461 acttccttcc ccagtaaaag cgattgaaaa acagggcatt acaatcatca aaacgttcga
    17521 tgcccccgga ggaatgaaag gttatctcgg aaagtatcag gatatgggcg tcaccatcta
    17581 cctgactccc gatggtaagc acgctatctc tggttacatg tacaacgaga aaggtgaaaa
    17641 cctgagtaac acacttatcg aaaaagaaat ttacgcacca gccggacgcg aaatgtggca
    17701 acggatggaa caatcccact ggctcctcga cggtaaaaaa gatgcgccgg tcattgtcta
    17761 cgtgttcgcc gatccgttct gcccatattg taaacagttc tggcagcagg cgcgcccgtg
    17821 ggtagattct ggcaaagtgc aattaagaac attgttggtt ggggttatca agccagaaag
    17881 cccggcgaca gcagcggcaa ttcttgcctc caaagatccc gcaaaaacct ggcaagaata
    17941 tgaatcctct ggtggcaagc ttaagctaaa cgtgcctgca aacgtaagta cagaacaaat
    18001 gaaagtgtta agcgccaacg agaaactcat ggacgatctg ggggcaaatg tcacaccagc
    18061 gatctattac atgagtaagg aaaatacgct gcaacaggcc gtggggttgc ccgatcagaa
    18121 aacgcttaat atcattatgg ggaataaata aaagataatt catggatggt tgaaatacat
    18181 ccctgctttt caaccatcct aaaaaagcat gaattgctcg ctctgcccta agtggctatg
    18241 ctattttaga aaaacttaat cctgagttaa gcaaaaaaaa tataatcaat aaaaatatat
    18301 acgcaaaaaa cattgattaa gtgaatatac catggaagaa aaatataacc ggagtagtgt
    18361 atggccaatc tctacgactt gaaaaagttc gacttaaacc ttcttgtcat atttgagtgt
    18421 atttaccagc atttaagcat tagcaaagct gctgaatcac tatatatcac cccatcagcc
    18481 gtgagccagt cgttacaacg cttacgtgcg caatttaatg accctttatt cattcgctca
    18541 ggaaaaggta tcgcgccgac gacaacaggg ttgaatctgc atcaccatct tgagaaaaac
    18601 ctcaaaggcc ttgaacaaac aattaatata gtcaataagt ccgaactaaa gaaaaacttt
    18661 attatttacg gccctcagct catttcttgc tctaataata gtatgctgat ccgctgccta
    18721 cggcaagatg cctctgtcga gattgagtgc catgatatcc tcatgtcagc agagaatgct
    18781 gaagaactgt tggttcaccg caaagccgat ctggtgatca cccaaatgcc agtgatcagc
    18841 cgttccgtca tttgcatgcc attgcataca attcgcaata ctctaatttg tagtaataag
    18901 catccgcgaa ttactgacaa tagcacttat gaacaaatta tggcagaaga gttcacccaa
    18961 ttaatatcca aatcagcagg agttgatgat attcaaatgg aaatagacga gaagtttatg
    19021 aatcgcaaaa tttcatttcg tggttcctct ttgctgacaa tcattaatag cattgcagtt
    19081 acagatttac tgggaatagt cccctatgaa ctttataatt cctaccgtga ctttcttaat
    19141 ttaaaagaga taaaactaga acatccgtta ccttcaataa agctttacat ttcctataat
    19201 aaatcttctt taaataattt ggtgttctcc cgatttattg accgtctaaa tgagagtttt
    19261 tgatatataa ctacagacag ctactataac tttcatctat ttattcacag cgcgaatgaa
    19321 aaataaaaca ctctgctttg cagtgtttac tttataatta acagacttat ctcactgatc
    19381 accctgtaac gttcagagag cgtcttcaga tgtctattta taaaattcct cttccgctca
    19441 atattctgga agctgcacga gagcgtatta cctggacact caacacccta ccccgcgttt
    19501 gtgtctcatt ttctggcggc aaagactctg gtttaatgct gcatctgaca gccgaacttg
    19561 cccgacaaat gggcaaaaaa atctgcgttt tgtttatcga ctgggaggcg caattctctt
    19621 gcaccattaa ctatgttcag tccctgcgcg agttgtacac cgatgtcatc gaagagtttt
    19681 actgggttgc gctcccgctt acgacgcaaa attccctttc acaattccaa cccgaatggc
    19741 agtgctggga acctgatgtc gaatgggtgc gtcagccccc gcaagatgcg ataaccgatc
    19801 ctgacttttt ctgcttttac cagcctggca tgaccttcga acaatttgta cgtgagtttg
    19861 ccgaatggtt ttcacaaaaa cgtccggcgg cgatgatgat cggcatccgt gcggatgagt
    19921 cctacaaccg ttttgtcgcc atcgccagtt taaataaaca acgttttgcc gacgataaac
    19981 catggactac ggccgcacca ggcggtcata gctggtacat ttaccccatt tacgactgga
    20041 aagtggctga tatctggacc tggtatgcaa atcatcaaag tctctgcaac ccactgtata
    20101 acctaatgta tcaggcaggc gttcctctgc gtcatatgcg aatttgcgaa ccttttggcc
    20161 cggagcaacg acaaggatta tggctctatc acgttatcga accggatcgc tgggcagcta
    20221 tgtgcgcacg agtcagcggg gtaaaaagtg gcggcattta cgccggacat gacaatcatt
    20281 tctatgggca tcggaaaatc ctcaagccag aacatttaga ctggcaagaa tatgcattat
    20341 tgctgctcaa tagcatgccg gaaaaaacag ctgagcatta ccgcaataaa atcgccattt
    20401 atttgcactg gtatcagaaa aaaggcatcg aggttccaca aacccagcaa ggggacattg
    20461 gcgcgaaaga tatcccctcc tggcggcgga tatgcaaagt tttactcaat aacgattact
    20521 ggtgtcgagc attatcattt agtcctacga aagcgaagaa ctatcagcgt tataacgaac
    20581 ggataaaagg aaaacgtcag gaatggggga tactatgcaa caacgattaa cgcaggattt
    20641 aacgcaattt ctcgccagct tgccggaaga tgatcgcatc aaagcgatta atgaaatccg
    20701 catggcgatc catcaggtta gcccctttcg tgaagagcca gtggattgcg ttctgtgggt
    20761 taaaaacagc caacttatgc ctaatgatta caacccaaac aacgtggcac cacccgaaaa
    20821 aaaactgctg aaaaaatcca ttgaaataga tggttttacc caacccattg tggtcacgca
    20881 tacggataaa aatgccctgg aaatcgtgga tggttttcac cgccatgaaa ttggtaaagg
    20941 ctcatcatca ttaaaattac gcttaaaagg ttatttgccg gtgacctgtc tggaaggtac
    21001 gcgtaatcaa cgcatcgccg cgactattcg tcataatcgc gctcgtggac gccatcaaat
    21061 caccgccatg tcggaaatcg tccgtgaact tagccagttg ggatgggacg ataataaaat
    21121 tggcaaagag ctgggaatgg acagcgacga agtgctgcgc ctgaagcaaa ttaacggcct
    21181 gcaagagttg tttgccgacc gtcaatattc ccgcgcctgg acggttaaat agctaaagct
    21241 ggcgcaggcg ttcagctgct gccagcaacg tcgattcctt cttggcaaaa cagagacgaa
    21301 tcagtttatg tgggaaggga tcggcgcaaa acaccgacag cggaatcgcc gctacgccgt
    21361 gctcctgcgt cagccactgg caaaactcaa catcatccag ggtagaaacc gcgctgtaat
    21421 ccaccagcaa aaagtatgta ccttcacacg gtaaaatctc cagccggctt tcatttaaag
    21481 cattcaccag aatatcgcgc ttctggcgat aaaagtccgg taacgcaaga taatgctcag
    21541 gttctgcacg tagcatatca gcaagcgcca gctgtgccgg ggtattcacc gaaaaggtca
    21601 gatactgatg taccttgcga atttcggcgc tgatgggcgc tggcgcaaca caataaccca
    21661 ctttccagcc ggtcatatga taggtcttgc caaatgaaga aaccgccact gcccgctcac
    21721 gcagctgcgg atgcgccagc acactggcat ggccctgttg tgaaaagttg atgtgctcgt
    21781 agacttcatc gctaatgaca aaaatctcgt gcccggcgat cgcctgccac aaagcggcga
    21841 aatcagcctg ctgccagata gttgcactgg ggttatgcgg agtgttgagg atcaccagtc
    21901 tggtgcgctc gcttaataat gcggcaaatt cctgccagtc aacgcgaaaa tgcggtggtt
    21961 gcagtgccat acgcttcact attcccccag aaagcgcgat ggcgggggag taactgtcat
    22021 agctgggatc aaaacaaatc acttcatcgc cattgcgcac cagtgcggta atcgccgcgt
    22081 ataacgcttc cgtcgcccct gccgttacgg tgatatcgct atcggcatct ggttgatagc
    22141 catacaaacg ttccgttttc tgagcaatcg cctcgcgcaa ggcctgcacg ccggtcatgg
    22201 gcgcgtattg gtttgccccc tgggcaacgt ggtacgccag ccgctcctgt aaatagtgcg
    22261 gaccatcaaa atcaggaaag ccttgcgaca ggttaatcgc ctggtgttgc tgcgccagcg
    22321 cgctcatctg ggtgaaaata gtggtgccaa gttgtggaag tttgctttgt ggaatcagag
    22381 ggttatttgt catttttatt gtacctgacg aagttgcgtg ttgaaggcac tataacacga
    22441 tgctagtatt tggcaatcaa gacgtttaga tgtctaaata aaacaataag gacaacacaa
    22501 catgcctcac aatcctatcc gcgtggtcgt cggcccggct aactactttt cacatccagg
    22561 aagtttcaat tacctgaacg attttttcac tgatgaacaa ctttctcgcg cggtgtggat
    22621 ctacggcaaa cgcgccattg ctgcggcgca aaccaaactt ccgccagcgt ttggacttcc
    22681 aggggcaaag catattttgt ttcgtggtca ttgcagcgaa agcgatgtac agcaactggc
    22741 ggctgagtcc ggtgacgatc gcagcgtggt gattggcgtc ggcggcggcg cactgctcga
    22801 caccgcgaaa gccctcgccc gccgtctcgg tctaccattt gttgccgctc cgacgatcgc
    22861 cgccacctgc gcagcctgga caccgctctc cgtctggtat aacgatgccg gacaggcgct
    22921 gcattatgag attttcgacg acgccaattt tatggtgctg gtggaaccgg agattatcct
    22981 caatgcaccg caacaatatc tgctggcggg gatcggtgac acgctggcga aatggtatga
    23041 agcggtggtg ctggctccgc aaccagaaac gttgccgcta accgtgcggc tggggatcaa
    23101 taatgcgcag gccattcgcg acgtcttgtt aaacagtagc gaacaggcac ttgccgatca
    23161 gcaaaatcag cagttaacgc aatcattttg cgatgtggtg gatgcgatta tcgccggggg
    23221 tggaatggtc ggtggtctgg gcgatcgttt tacgcgtgtg gctgcggccc atgccgtgca
    23281 taacggtctg actgtcctgc cgcaaaccga gaaatttctc cacggcacca aagtcgctta
    23341 cggaattctg gtgcaaagcg ccttgctggg tcaggatgat gtgctggcgc aattaaccgg
    23401 ggcgtatcag cgttttcatc tgccgactac gctggcggag ctggaagtgg atatcaataa
    23461 tcaggcggag atcgacaaag tgattgccca caccttgcgc ccggtggagt ccattcatta
    23521 cctgccagtc acgctgacac cagatacgtt gcgtgcagcg ttcgaaaaag tggaatcgtt
    23581 taaagcctga cgtgcaaatt tagcagcagc gcgcgccgcc ttttccaccg tagcgcgcgt
    23641 cctgccgctc acggaaaaac tcctcgtagg tcatcggcgt ttgatcggga tggttaaccc
    23701 gcatatgttc gacatagttg tcgtaatcag gcataccaat catcagcttc gccgcctgac
    23761 ctaaatattt tccggctttt gccagtgaat caaacatctt ggcctccgct aaccatgttg
    23821 ctgaaagagt gccggatgcg gcgtgaacgc tttatccggc ctacaaatgc tatcaacgca
    23881 ctcggtcagt cccctcgccc catcggggag agggttaggg tgagggggaa ccctcggcac
    23941 tatgccaaca ttcgccaaca tcccccctca ctctgacttt agtgcgcacc tttcgcctgc
    24001 gctacgatct cctcaacatt ttccggcatt ggctcatacg gcgtttcttt cgccgttggc
    24061 ttcggctctt tcaatgccgc aagtgccgtc ttaatcgaga acagtgccag aaccaccacg
    24121 accaccataa agaagatggt taacccggca tccagacggt tgttgaacac cagttgcgcc
    24181 agctgtgact cagtatactg cgacggaata ttgccgctgt cgatcattgc ctggaacttg
    24241 ttagcaatgg ccaggaagcc gactttcgca tccgggctaa acgctttctg ccagcctgcg
    24301 gtcagggtac aaatcagtag ccaggccgtt ggtaccagcg ccacccaggc gtaacgttga
    24361 cgtttcatct tgaacaacac cacggcacag agcatcagcg ccatccctgc cagcatctgg
    24421 ttggcaatac caaacagcgg ccacagagtg ttaataccgc ccagcggatc gaccacgccc
    24481 tgatggagga agtagcccca cgccagtacg cacagcgccg ttgccagcag gttagcaggc
    24541 agtgaatcgg tccgcttcag gccaggagac accacgccca gcagatcctg caacataaag
    24601 cgcgcagcac gcgtacccgc atctaccgcc gtcagaataa acagagcttc aaacagaatg
    24661 gcgaagtgat accagaacgc cacatccatc ataccaccca gcgcaccgtg caggatgtaa
    24721 gccatcccca ccgccaacgt cggcgcaccg cccgcacggg aaatgatcga ctgttcaccc
    24781 acttcgctgg caatctggtt gagcgtatct ggtgtaatgc taaagcccca gctactcacc
    24841 acctgcgcgg cagaagcgac cacatccgcc gtccctgccg gagccagcac cgccattggg
    24901 ctgttcatgg caaagtaaac gcccggatcg atgatacagg cggaaaccag cgccataatc
    24961 gccacgaagg attccatcaa cattccaccg tagccgataa aacaagcctg cccttcgttc
    25021 gccagcatct tcggcgtggt gccggaagag atcagcgcat ggaagccaga caccgcgcca
    25081 caggcgatgg tgataaacag gaacgggaac aggttaccgg tccataccgg gccagtgcca
    25141 tcgacaaatt tggtcagcgc aggcatggtc agcgtcgggc gcataatcaa aatgcctacc
    25201 gccagaccga cgatcgtccc gattttcagg aaggtagaga ggtagtcacg cggggccagc
    25261 agcaaccaca ccggcagcac cgccgccaca aaaccgtaac ccaccagcat ccagatcagc
    25321 tgcacgccgg taaagtcaaa gtacggtgcc caggtcggac tttctgccac ccagccgcca
    25381 gagataatgg cgaaaatcag gaataccaga ccgatgaccg acacttcacc aatacgcccc
    25441 ggacgcagat agcgcaggta gatccccata aacagcgcca gcggaatggt gaacgcaacg
    25501 gtatacgttc cccacgggct atgagtcagg gctttcacca cgatcatcgc cagtactgca
    25561 aggataatga ccatgatcat aaagcaggcc accagcgcta tcaccccggc ggttggcccc
    25621 atctcttctt tgaccagctc acccagcgat cgaccgtcac ggcgcgtaga aacaaacagc
    25681 accatgaaat cctgcaccgc accggcgaga accaccccgg cgagcagcca gatcatccct
    25741 ggcaggtaac ccatttgcgc cgccagtacc ggcccaacca acggacctgc tccggcaatg
    25801 gccgcaaaat ggtgaccgaa cagcactttc ttgtccgtcg gcacatagtc cagcccgtcg
    25861 ttatggcgca ccgctggcgt catacgcgtc gggtcaaccg ccagcacatt tttggcgata
    25921 tacagcccat aaaaacggta agcgatcaga tagatacaga ccgacgccac cacaatccac
    25981 agcgcgttga tctgttcccc acgatttaaa gcaatgtatc ccagagcaaa tgctcccatt
    26041 acagagagca ctgtccagac gaggtatttc cctgatttgt tcatagttgt tatccgtgtg
    26101 cgtgtccata gatatgttac attttgtttc tataacatct ttgtacgatt taacaacacg
    26161 gtaaccatgt aaatcggagt tgaaaccaat atttaactta acaatgttaa ctcgatcact
    26221 ccgttaaccg agttttcctg caatctcatt taattctgtc gggctcatcc caaaactgcc
    26281 gtacccagcc gacaagtgca gcaacgccgc ccctgttcat cgaaaacgac gatttcccag
    26341 ctctgatttt gccgcccaag atgcagcggc tggcagacgc cgcgtacctt gccttcagac
    26401 accgggcgat gatgggtggc gttaagttcc gtacccacca cacactgccc gtcacgggtc
    26461 atcataaatc cggccatcga tcccagcgtt tcagccagcg ccgctgacgc gccgccatgc
    26521 agcaggccaa acggctgatg agtacgggta tcaaccggca tttcggcttc cagcacatca
    26581 tctcccagac gggtatacac aattcccaga tgcgccacca ttgtgttatc gctggtggcg
    26641 ttcagttcgt cgagcgttaa atggcgtttc cagatcatgc ttatgccccc agcgttgagc
    26701 cgccatcgac cacaatatcc tgtagggtga tatggctggc gaggtcagag gcgaggaaca
    26761 aaatcgtgtt ggcgatctct tgtggacggg cgattttccc cagcggaatg ccgagtttaa
    26821 actgctcgcc aaagccgcga atacgctgtt cttcggcgtc atcgctcacc cacagcgtgc
    26881 gttgcatatc ggtgtcggtg gagccaggcg aaaccacatt acagcgcacg ccgctacccg
    26941 ccagttccag cccgacgctc aacgccaggc ttttcagcgc cgctttcgat gcgccataag
    27001 cactcatgcc aatacgcggc gtgtgcgcgg cgtcggacgc cacagtgaca atcgccccgc
    27061 cccgctgacg gcgaaactgg ttcatggttt gctggaacag gttaaacgca ccgccgacgt
    27121 taaccgcaaa agtctgctgc cagtcctctt tactgagctg atcggtcgcg cccatgcgca
    27181 aaattcccgc cgcattgacc agcacgtcca gtcgctccgt ttcagctaac agtcgctgac
    27241 atacctgcgc gacctgcgca gcatcggcaa catccatcac ttcggtcgca aagggatatt
    27301 gctcctgagc gaacgcttga tcaaaagcgg taactttcgc tcccgcctca acaaacgcca
    27361 gcgccgtggc gtagccgata cctttacctg cgccggttac ccagacattt ttaccgctga
    27421 aatccattat ttcacctcgc gggagagtag cttccaccag gcgtcgatgg tcgggttttt
    27481 cgccagcatg acaaagtcga tatcaccatg cactttgcgc cagcgcgccg ccagcgccat
    27541 catgcgcacc gaatccagac cgtagtcgat caggttgtcg tcatcgaacg gttcatcgga
    27601 ctcgtccagc aacggcagga taacctcacg cagcgccgct ttgctggcgg ggacaggtgc
    27661 tggcagtaat tcttcagtca tcaccacccg gccagaccgc ccggccacat atttcagcga
    27721 catcaaatgc tcgtcacggc tgaaatcggc cagcgcatcc gccaccataa acggtttaat
    27781 atcgcgcata aatgcgtcgg ttgcggtggt catacagcca atgtgggcat ataccccggt
    27841 aataatcagc tggttacgtc cactctcttt gagcatttgc tccagcggag aacgatgaaa
    27901 cgcgctgtag cgccacttca ccagcaccgt gtcgtcggca tctggcgtca ggcgatccac
    27961 caccttttgc tgttccggcg aacgggtcag gcccggcccc cacatatcat tcaacagcgc
    28021 ccgatcttca tcgctctgct ctttcggctg ggcggtgtaa taaaccggaa tattgtgctg
    28081 tttgcagtag tcgcgcagcg cagcaatatt cgcgatcacc tgctccatca tcgggcagtt
    28141 ctcgccccag aagctgacaa aatagtcctg catatcatgg attaacaacg cggcacgttg
    28201 cggttcaaag gcccagtcaa ctttattctt agggatatcg tgagactccg gcagtgcgta
    28261 agcctgtaat tttggaatag ccatcgtgtt ctctccttca ggctgatgcg cgtgacgcca
    28321 gccactgacg taattgtttt ttatcgactt tcccgaccgc cgtcagcgga agtgaatcta
    28381 cacactccac gcgatccggt aatttaaatt cggcaatacc ctgttcacgc aggaaacgac
    28441 gcacctgcac cgcgcgcagc ggctctttta ccaccagata agcgcagctt ttttcgccca
    28501 tcagctcatc ttccatgctc accagtgcgg cgtagatcac cgccgggtgg cgcagcagca
    28561 ggttttcgat ctcttcggca gcgatcttct caccgccacg gttgatctga tctttctcgc
    28621 gcccctgcac ggtgatgtac ccctctggat caatagagat cagatcgccg gaacagtaaa
    28681 aaccgttggc atcaaaggca ctggcattgt gctgcggact tttgtaataa ccgcggaagg
    28741 tgtacggccc gcgcgtcatc aggcgtccaa cttccccttg cggcagtgga tttccttcag
    28801 catcagcaac ccatacttca tcgtccggac acattgggta accctgggta tggataattt
    28861 tctccgcgct atcatcaagt cgggtgtagt tcaccagccc ttccgccatg ccaaacacct
    28921 gctgcaacag gcagccaatc tcagcgggaa tacgcgccgc aagggtggct gaaagacgtg
    28981 cgccgccgac ctgtaacagt ttcagcgagg caagctgcgc ccggctttca ccttcggtca
    29041 gcgcctgcaa ccacaggctg actgccggtg gcaccagcgc ggtgacgttc acctgatgtt
    29101 tttcaatcaa tgggaagcaa agcgtggcgc tgggatcggc cgccagaaca agcgttcctc
    29161 cggcaagaaa gacgcccagc gatcccggcg aactcatggc gtagttatga gccgccggga
    29221 tcgcgcacag gtagcgtgtc tgttgtgtga actgacaaat ctcgacgcta cgacgcacgc
    29281 tgtagtagta gtcgttatga gtgcgcggga tcagtttcgg tgtgccggtg gtgccgccgg
    29341 aaagctggaa ataggccact tcatcagcag gtgatggcgt ggcagtaaaa tcctcagccg
    29401 gatggttaat cgcatcctgc aagttatgct caccgctgtc gttgtgcagt tgcaccacgc
    29461 gaatggagga atgttctgtg acgaaagtat tgaggaaatc atccccgcta aacagcgcat
    29521 gttggcgatc ggcaatcagc aatgcgggtt caatctggct ggcataggcg ttcagttcac
    29581 tacgctgatg gctgaacagc gccagcaccg gcgcaacgcc cagtttcagc agcgcgaaaa
    29641 aggtaatata caattcagcg acgttaccca gttgtaccag cgcggtttca ccaggtttaa
    29701 tgccctgacg gcgtaaacta cacgcgaggt tatccgccgc ctgattcagc tcccggtaac
    29761 tcaactgtcg ctcgccgtcg ataaccgcga tgctgtcact cgcagcgtgg cgagtcagaa
    29821 tgtcggtcag cggcaaatcc tgccagtagc ctttttcccg atagcgacgg gcaaactctt
    29881 ccggccagcg ggtgaatgga atgctcatcc tcgctcctta atgcaatcca aaaacgttca
    29941 acatggtaga aagtttgacg cctgtttcgc gccactcacc caacggtgac gacgcaggca
    30001 caatccccgc tccggcaaac agacgcacct gattttcccg cagcttcgcg cagcggatgg
    30061 tcaccaccca ttcgccgtta ccttcgctgt cacaccaacc cacaatgccg ccaaacagtt
    30121 cgcggtcgaa tggctccagt tcagcaataa cctgggtcgc ggcctgatgc gggaaaccgc
    30181 tcagcgcggg ggttggatgc agcagacagg ccagagtcag tgcgttttct tgcgaattcg
    30241 ctttaccttc aaagggagtt gcgagatgcc acagcgtcgg cgtggtaatc aattgtggag
    30301 aggagggaac gtgtaactca ctactgcgtt cgcgcagtac ctctttcatc gcctgagtca
    30361 ccagttcatg ttcatggcga tctttttctg acgccagcag acgattaccc gcttcgcgat
    30421 cgagcacttc atccggctga cgacgcgcgg aaccggctaa cggaatggag ctaaaacgct
    30481 cgccgtcttt acgtagcagc agttccgggc tggcccccag caggacgcca ccatcagcca
    30541 gcgggacatg gaagttgtaa ctaaccgggt tttgcgcaat caaccgttcc agcaatacgc
    30601 cactatcaat ggcggcgtca gtggtgatat caatcaatcg tgacaacacc actttgtcga
    30661 cctgcggcgt ggcggtaagt gcggcggcgc gggcaaccat ctgttcaaac gtggtttgtt
    30721 caggaattgc ctggcgttcc accacgttca gcgactggct gcgggtaaaa cggcgggctg
    30781 aggtctgttt ttcctggcgg gagaacgact gccaggattc gggaatatac agcgacgaag
    30841 gctgacgtgg atcgaaggga atcgccccga ccatcaccgg atttttgatg ccctgcgctt
    30901 tggcatcggc aaacagcgcg gcgagttttt gctggaaggg actgtcgggc gaatccccgt
    30961 tcacagccgg ttcatcgaag cgggcgaaac atcctgacgt cgtaaaactg cggtacggcg
    31021 acataaagaa aaagcgattg ggcgcaagtg ttgccatggt ctgctgtact tcctcagcca
    31081 gtgacgtatc catatcatcc tccacaaaat gataaaggct ttaataatga ttatcattta
    31141 tattttcggt cgctaaccta aaagcaaacg cgcactatgt caactcttga ggtaacgcaa
    31201 tctgcaactc ggggttgcat ctggttgtgg ttacaatgaa aatgagaagc attattgatg
    31261 gattcgcata agcgcaatgt gatgtcctgc gccgttctgc cccctctccc ttccagggtg
    31321 agggctgggg tgagggttaa tgttcgcacc agtgctggct gttcccctca ccctaaccct
    31381 ctccccaaag gggcgagggg acggattgtg cgctttgtcg aatttgtcat tacgccctta
    31441 accttattaa taacaggaag ctgatttgtg agactcgccc cgctctaccg caacgccctt
    31501 ctattaacag gacttttgct ttcaggaata gccgcagttc aggccgctga ctggccgcgt
    31561 cagattactg acagccgtgg cacacataca ctggaaagcc agccgcagcg tattgtttcc
    31621 accagcgtca ccctgaccgg ctcactgctg gcgattgatg ctccggtgat cgccagcggc
    31681 gcgaccacgc cgaataaccg cgtcgcggat gaccagggct ttttacgcca gtggagcaag
    31741 gtggcgaaag aacgcaaact gcaacggctc tatatcggcg aaccgagcgc cgaagccgtt
    31801 gccgcgcaaa tgccggatct gattttaatt agcgcaaccg gcggggattc ggcgctggca
    31861 ctgtatgatc agctttccac catcgccccg acattaatca tcaattacga cgacaaaagc
    31921 tggcagtcgc tgttaacgca gcttggcgaa attaccgggc atgagaaaca agcggcagag
    31981 cggattgcac agtttgataa gcaactggca gcggcgaaag agcaaatcaa attaccgccg
    32041 cagccggtca ctgccattgt ctataccgcc gctgcacaca gtgccaatct ctggacgccg
    32101 gaatcagcac aagggcagat gctggaacaa ctcggcttta cgctggcgaa gttgcccgca
    32161 gggttaaacg ccagccaaag ccagggcaaa cgccatgaca tcattcagct tggtggggaa
    32221 aatctggctg ctgggttaaa tggcgagtca ctattcctgt tcgccggtga tcagaaagat
    32281 gccgatgcga tttatgccaa tccactgctc gcgcaccttc ccgcagtaca aaacaagcag
    32341 gtttatgcgc tgggaaccga gacgttccgt ctggattact acagcgccat gcaagtgctg
    32401 gaacgactta aggcgctgtt ttaagcatta actgtcagac gctgtcacct gcggcggcgt
    32461 ctggcgaaaa cgtcgcaact ccaccagcac cagcaataac aacacgccga taatcaacaa
    32521 accaaaaccg ctcgcgcttg cggaagcaac cggtgtcatc atcgcgccca aaccacccag
    32581 cagcgccgcg cctatggcat cgcccgtcac gttctgcgcc gtccacaaac cgttaatccg
    32641 ccctaacatc gcttccgggg tttgcgtttg cagcattgta tattgcagca acgaactaac
    32701 cgcgctcagc cagccgaaca gcgccagaca aaccacgcct aaaatccaca tcggcatcag
    32761 gccaaacaga ccaatggcga ggaacgatcc cagcgtggag agcagcatca ataaccctgg
    32821 tcgcgcacta tgtgccagct tcccgctggt taacgcacca atagccgcgc cgagcgggat
    32881 cgccgcgtag agaaaaccaa tctgtgccgc tgacatctgc cagttgtcag ccagcgccgg
    32941 atacagtacc cgcaccgcgc tcgccatcgt caataaacca cccagcagcg caatcccgcc
    33001 caccagcggg ctggcaagca gaaaacgaaa tcctgccagt aatgatttca acggatgctc
    33061 acgcggctgc ggtggcggtg gcaacgccgg aaggcttaac aacggtagca aggtaataaa
    33121 cgtgcccgcc gccgccagcc cgtagttcca ggctacgcca ccggtcgcca gcaataaacc
    33181 gccaatcatg ggcgaaatca ccgaccccag acgcacggtc aacatggtga tcgccccggc
    33241 ctgcattaag ttttcacgcc ctaccagtgc aggtgtcgcc gccagtagcg ccgtaacgcc
    33301 aagtgatgcg aaaaaaccat cccataaacc aagtaaatag attgccagca atgacggttc
    33361 aggcagcagt gcattaaggc acagtccaat gaagccaatg ccacaggtgc cgcgcgccag
    33421 caaaatcact tttttgcgtt catagcgatc cgccagcaca ccgccgacca tcaggccaac
    33481 aaacatcgcg ccgccggtca gcgtcaccga aagccccacc tgccaggtag aatgtgtcat
    33541 catctggatc tgcaccggca ccgcgacgcc gagcaaaccc agagaaacaa tagagatgaa
    33601 acgagcgagg aatactgcgc gaaacgccgg gtgcgttttc aacaggctga ggttaagcag
    33661 ccaggattgt ttattcatta caatgccttg ccatcaaata ttttaaatac ctattcttag
    33721 gctgcacatg ctaacatatc caaataagat cgataacgat aattaatttc attatcatgg
    33781 aagttcgtat gtctggttct gttgccgtga cacgcgccat tgccgtgccc ggattgctgt
    33841 tattactgat tatcgcgacg gcattaagtc tgctcattgg ggcaaaatca ctccccgctt
    33901 ccgtagtgct ggaggccttc tccggcacct gccagagcgc cgactgcacc atcgtgctcg
    33961 acgcgcgtct gccgcgtacc cttgccggtt tactggcagg cggcgcgctt ggccttgccg
    34021 gggcgttaat gcaaaccctc acccgtaacc cacttgccga ccccggcttg cttggcgtga
    34081 acgccggagc cagctttgcc attgtgctgg gtgcggcgct gtttggttac tcttccgcac
    34141 aggaacaact ggcgatggcc ttcgccgggg cgctggtggc ctcgttgatt gttgccttta
    34201 ccggcagcca gggcggcggg cagttaagtc cggtgcgttt aaccctggcg ggcgtggcgc
    34261 tggcggcggt gctggaagga ctgaccagcg gcatcgccct gcttaatcct gacgtctacg
    34321 atcaactgcg tttctggcaa gccggttcgc tggatattcg caatctacat accttaaaag
    34381 tggtgctgat cccggtgctg atcgccggag caactgcgct attactgagt cgcgcgctga
    34441 acagtttgag cctcggcagc gacaccgcga cggcgctggg cagtcgcgtg gcgcgcacac
    34501 agttgattgg tctgctggcg attaccgtgc tttgtggtag tgcgacggca gtagttggcc
    34561 cgattgcctt tattggcctg atgatgccgc atatggcgcg ttggctggtg ggtgccgatc
    34621 atcgctggtc gctgcccgtc acgctacttg ctacccctgc cctgctgctg tttgccgata
    34681 tcatcgggcg ggtgattgtg cccggcgaac tgcgcgtttc tgtggtcagt gcgtttattg
    34741 gtgcaccggt gctgatcttc ctcgtgcgac gtaaaacgcg aggtggtgca tgatttacgt
    34801 ctctcgccga ttactcatca cctgtttgct gctggtttcc gcctgtgtgg ttgcaggtat
    34861 ctggggatta cgcagcggtg ccgtcacgct ggaaacctcg caggtattcg ccgcgctgat
    34921 gggcgatgcg ccgcgcagta tgacgatggt ggtcaccgaa tggcgtttac cacgcgtgct
    34981 gatggcgctg ttgattggcg cagcactggg cgtcagtggc gcgatttttc agtcgctgat
    35041 gcgtaacccg ctcggcagcc ctgacgtaat gggctttaac accggggcgt ggagcggcgt
    35101 gctggtggcg atggtgctgt ttggtcagga cctgacggct atcgcgctgt cagcaatggt
    35161 gggcggcatt gtcacttcgc tgctggtctg gctgctctcc tggcgcaacg gcatcgacac
    35221 ctttcgattg attattatcg gtatcggcgt tcgcgccatg ctggtggcct ttaatacctg
    35281 gctgttgctg aaagcgtctt tagaaacggc gctaacagca ggtttgtgga atgccggatc
    35341 gctcaacggc ctgacgtggg caaaaacctc gccttccgca cccatcatta tattgatgct
    35401 cattgccgcc gccttactgg tacgccggat gcgcttgctg gaaatgggcg atgataccgc
    35461 gtgtgcgctg ggcgtcagcg tcgaacgttc gcgtctgtta atgatgctgg ttgcagtggt
    35521 gcttaccgct gcggcaacag cgcttgccgg gccgatttcc tttattgctt tagtcgcacc
    35581 gcacattgcc cgacgcatta gcggcaccgc tcgctggggg ctaacccagg cggcgctatg
    35641 cggggcgctg ttactgctgg cggccgatct ctgcgcccaa caactgttta tgccgtatca
    35701 acttccggtt ggcgtcgtta ccgtcagcct cggcggtatt taccttatcg tcttgttaat
    35761 tcaggagtct cgcaaaaaat gaccgaatca gtagcccgtt tgcgcggcga acagttaacc
    35821 ctcggatatg gcaaatatac cgttgcggaa aatctgactg tagaaatacc tgatggtcac
    35881 ttcacggcaa ttatcgggcc aaatggctgc ggtaaatcca cgttactgcg taccttaagc
    35941 cgcctgatga cgcctgctca tgggcatgtc tggctggatg gcgagcacat tcaacattac
    36001 gccagtaaag aggttgcacg ccggattggt ctgttggcgc aaaatgctac cacgccgggc
    36061 gatatcaccg tgcaggagct ggtggcgcgt ggacgttatc cgcatcaacc gctgtttacc
    36121 cgctggcgca aagaggatga agaagcggta acgaaagcaa tgcaggccac gggaataact
    36181 catctggcag atcaaagcgt ggataccctt tctggcggac aacgccagcg cgcgtggatc
    36241 gcgatggtgc tggcccagga aacggcaatt atgctgctcg acgaacccac gacctggctg
    36301 gatatcagtc atcagattga tttgctggag ttgttaagcg aactgaaccg cgaaaaaggc
    36361 tataccctgg cggcggtgct gcacgatctt aatcaggcct gtcgttacgc cagccatttg
    36421 attgcattgc gggaagggaa aattgttgct cagggagcgc cgaaggagat tgtcactgct
    36481 gaactgattg agcgcattta tggtctgcgc tgcatgatca ttgacgatcc agttgccgga
    36541 acgccgcttg tggtgccgct cggacgaacg gcaccttcaa ccgcaaatag ttaaactaag
    36601 tggtctgcca tcatggcatc ctgttttctg gatgccatcg catagcgcaa cagcacgcca
    36661 ccacaagcca ccatcccgcc gatcaacgcg gaaaggatca caataatcgc cttacccgga
    36721 ccgtcttttt tcactggcaa tgacgggctt aactgatatt taaacggcgt aaaattcaca
    36781 tcgttgacat gtgcttttgt taattgctcg acaagatact gccgattacg taattcaccg
    36841 ttcagttccg caacgtcagt gaccgctttt tctatttcca gtttgcgttc aataccgtct
    36901 gcaccgagag aaatagaaaa atcggggtca tctttaacgg cctgaccatt actgtaaacg
    36961 ggctttttaa ttcctgccgc gttggcaatg tcgagtgaat aattgaggcg ctgaatgttt
    37021 gcatcaagtt gatttttcgt tttaatgcga tcctgagcca gtttttcttt ttcaaactgg
    37081 gttttgatct ccagtttatt acggacgttt tctagcgact ctttcaccac caacgtagag
    37141 atataatcga tatacccgct caaaacggtc tgcgcctctt cactggttgg cgcggtaaaa
    37201 cttagcgtcc aggaggtata cagtgacggt tcatcttttt tcttactggc attgtcatca
    37261 accgctttca ttttttcgct caatgcgaca attgcgcgat gcaaatccag ttcgtcgatt
    37321 ttcgcctctt ttaattggtc catcacataa ggtgatgaac gcaggtactc ttccagcaag
    37381 ctaaccgact gaaacttctt gataaacagg ttaaatgctt ctgtacgatc aattttgata
    37441 tccagatcca gcacacgaag cttagtgaat gttttctcca actcttgcca ctgaacaggt
    37501 tctggaggcg tgacaaccgc cgcgctggtc catttttgcg gcaggatgaa agagatcagc
    37561 aagcctgcgc aggcaaacgc aaaaacgacc gccatgaccg tttttttggc ccgccataaa
    37621 actgagatta gattaagtaa atcaatttca ttattactgg gcgacgccag aggataatcg
    37681 ggaaaatgag cgtcacttcc ctgtttaata ttcagtgatg acatggggta taacctgaaa
    37741 atgagtccaa tagggggaaa tctccacggc gctcacttta ccagttggtg agaattatcc
    37801 gaagctgaag tttgtaaatt ccttccaatg aatgcaacat tcactctatt taagagaaat
    37861 aaccagcaaa cttataaatt aaacaaatga ttaacccata attatttcct gtaattatgg
    37921 gttaatagat aatgttaatt tacctgttta gcgttgcgcg aataatcggc ccaatttttt
    37981 caaacgcccc tggagagata atatccacat gcgcacaatc ctgacgatag atatccagtt
    38041 ccgctatcca cggcgaccag gcgcgttcgg gactcatacc ttcctgaagt gtgcgttcag
    38101 caacaaacag cgtcgcttta ccgtcaaacg gtacgctatg agcagtcgtc agcaggcgca
    38161 cagcatcagc gtagttgcct tcaatggtgg taaacaactc cgttgaagta cttccctgct
    38221 gtgctgccag gaaggcctcg cgttcgcggt taatctccgc cagcacttcc gggtccagac
    38281 cattagcttc tttttcctgc cagttttgcg tttctggcgg ccaggtatcc agcaagccaa
    38341 gaaatgccac ctgttcgcca cgggcacgca gtcgcgccgc aataccctgc gccagcgtac
    38401 cgccaaggga ataccccagc aggtaataag ggccatgcgg ttgttgttca agtaacgttg
    38461 ccagatgcgc ttcgcagact tcatccaggt ttgccgccgt ctgcatgggg ccattggggc
    38521 gcggtgactg aatgccgata atcgaccatt gtggatcgag ataacgcgag agcacgctga
    38581 actgccaggc aaaaccggac gcaggatgga aacaaaacag cgtcgggcca ttaccttcac
    38641 gcaacggcag aatggtttcg aatcccatac gccgggtgct gtcttcttca gcatcaataa
    38701 tcgttgccag tttggcgaca gttgacgcga ccatcacttg ccccggcgtc acctggcggg
    38761 caacctgccg acttaactgc gctgccagtt tcattgccag tagcgaatga ccgccaagcg
    38821 cgaagaaatc agcatcggca tcctgcacgt cacaccccag caacgacgag aatgccgcgg
    38881 cgataatcgt ttcactgccc gctttcggcg cacgccctgg cgcttgtgcc ttcagttcag
    38941 gcaacggtaa ggctttgcga tccagcttgc cgttggcgct aagtggtaac tgtggaagtt
    39001 gcagcagaac caccggtacc atatgtggtg gcaatgtttc acgaagctgc gcctgcaatg
    39061 cgctggtatc caacggcagg cccgattgcg acaccagata gcccaccaat tgacgcgcat
    39121 caccaccggt ggcagccgcc tggttaatca cacaggcgtg ggtaacggct tgttcgacat
    39181 ccggcagcgc ctgcatcacg cgatcgattt cgcccagttc aatacgctgc ccgcgaattt
    39241 ttagctgatc gtcactgcgc ccgaggtact ccaccgcgcc gttatccagc cagcgggcaa
    39301 cgtctccggt acggtacatc cgttcaccag gagcaaaagg atcggcaata aagcggctgg
    39361 cggtcagatc gggtcgtcca agatacccct gcgccagttg aataccggtg agatagagat
    39421 ctcccgccac acccggcggc accggatgca tcatcgcatc aagaatacgc aggcccgtgt
    39481 tccacaccgg ataaccaatc ggcacactgc tgccgcgcac ctgtgccagt tcctcgccaa
    39541 aagccggata ccagctgaca tctaccgccg cttccgtcgg gccatataga ttatgcaacg
    39601 gcgcgccagt taactgttgc cattcgcggc ataaatcagc cggtaaggcc tcaccactac
    39661 agaaaacctg tttcaacgtc gcgcaactct ggcgagcggt ttgcggcgtc agcgaggcaa
    39721 caaatgccgc cagcatcgac ggcacaaagt gcgtggtcgt tacgccatat tcggcaaaga
    39781 attgctgcat agcgagcggg tcgcggtgcg cttccggttc agccatcacc agttttgccc
    39841 ctgcgataaa cggccagaaa aactcccaca ccgagacatc aaaactgcac ggcgtttttt
    39901 gggcaacgac atcttcgcct gtaagcggat aatgattttg catccaaagc aggcggttga
    39961 cgatagccgt ctgcccgacc attacccctt tcggcctgcc ggtggagcca gaggtaaaga
    40021 tgatataagc cgtgtgatgc ggttgtgaaa gttgcagcgg cgcactgccc tgcggtgtaa
    40081 gcggggcgtt atagcaaagg ttggttaaat ctggaacatc ggcaaagcgc ggcagttgat
    40141 cgtcggtggt gattaacagc gacggacgcg catcttctag catcattttc aggcgatcgt
    40201 ccggataacc ggtatccagc ggtagccagg ccgcacctgc ttcaacaatc gcatgtagcg
    40261 ccagggtcaa aaagaccgag cgcggtagcg ccaccgctac gctgtcgccc ggtttaacgc
    40321 cgcgctcacg cagcagattc gccagcgcca ccacctgctc acgcatttcc cgatagctga
    40381 actggtaatg cgcatctgcc agcgccggag catccggagt ttttgccgct tgttctgcca
    40441 ccagagcgct aagcgtggtt tctggaatct caacctgagt ggcgttgatc tgcgccagct
    40501 gcgcgtattc acctggcagc ataatatcga catcaccgca caacagcgcc ggatctgcgg
    40561 cgaactgggc aatcagcatt ttcaggcgtt cagcatgctg gattaacgtt ggctcagcgt
    40621 aacgctgttt attggcgagg atctcaatac tcaaatcacc gtgtacatcc gggaacaggg
    40681 ccagttcaag gtcattaacc ggaccggttg ccagggtatg ggtttgcgcc tgaacatcag
    40741 gaatatccag ttggtaatca aataccttga tattgagtac cggaccaaac agcggttcat
    40801 cacctgccgc tcgcccgctg tcacggacaa tttgttcggc atcgtaacgt tgatgacgac
    40861 gcattttttt cagttgtgct gccagtcggg ttgccagttc cggcagcgtt tcttgcgccg
    40921 caatgtgaat acccaacggc aaaacgttga gcacgggtcc ggtagccgtc agcgccgccg
    40981 agcccagtcg acgcataaag ataaatccgg cggcgtagtc catacgattg cacaatcgcc
    41041 ccagccacaa ggctgccagc gcaagggcta aatcggtacg ctgcacacct gaaagttgcg
    41101 tagccagctg gcggaattcc ccgtcggtaa attccagttt caggcgcaga atatctgccg
    41161 aggcgctgcg ccccggtaaa ggtgccggag aaagtgacgc gggcggcggc agttgacgac
    41221 gctgttctgc ccagaatgcc gcatcacgct gccaggcttc gctttcgcgg tattgctggt
    41281 actcttccac tacatcagcg aaaggcgtaa acggcgaagc aggcgttggt tcgccacgca
    41341 gccatgtgca gtaaatattg gcgatctggc gagtaatggc cgggaaactg aagccatcga
    41401 ccagcaaatg gtgataacgc tgataccagt accagcggtt atccgcaaca tgtatcagct
    41461 gatgaaagac cagtggttta ccgctatcga cgcgcaaatc ttgttgcaaa tccgccagca
    41521 ttaatgcctg cgcagtaccg tgcggatcaa tattggttcg caggtcgata atttctggca
    41581 gttcgaatat cagcgcatca tcgacccact gccagacttc gccgttatct tccgtaaaac
    41641 gcatccgcaa cgtatctgct tgcgctagtc cgacaaccac cgcgcgggcc agtaatggcg
    41701 catcaacatc tccagttaac tcaacgtaat gcgccacgct ccaggcggag ggtaaatccg
    41761 acagtttttc tgccatccag atgccgggct gtgcggcgac caaaggtaaa tgctggctca
    41821 ttgtgcctcc tgcaactggg tgaaattggc cggtgtcaga gtacgccagt ggacttccag
    41881 ccactgctgg caggacgcct gtgactgcgg ctgacacaca atgtcccagc ctgccggtaa
    41941 ggcgcattgt tgcggccaca gactgaattg cccctgcgca ttgcgcaaaa tgtaaaacgc
    42001 tccctgcgga tcatcgaagg gattactgaa tgccatattc aactcctgtc atggaaaagt
    42061 ggttgccaga ggtcgattag cccctgcatc aagccaccgc gccaacaaag cgcatcatgt
    42121 ccgccgtcaa cctgacgcca gaaaatggat tcttttatgg ggtgtaattg cgcatacagc
    42181 gcctgattgg cccgcattat catcggctcg cgaatacccg cttccagcac aatgcgcaga
    42241 ccttcggcac taacttgacc agctttaagt tgctcaagta aaacaccttc ttgctgcccg
    42301 ccccgatgcg gccaccagta cgatcctgac tggcttaata cacagccaaa gcgttcaggc
    42361 cagtgcagtc cggcatacag cgcggaaagt ccaccaaaac tctgcccggc gaccacggtg
    42421 cgatcggcgc gatcgctaaa aggggcaata gctttcacca ggggtaataa ctcttgctgt
    42481 actgccagcc agaaatccgc attacacggc agttcgtgag cgcggtgcgt agtgtcgata
    42541 gcgtcgatca acacatacac ggcgggagga agttgctgac gatgggtcaa cgaagtcagc
    42601 acaggccaga caggcatact ctgcgcccaa aattcgccat cgagcaaaac tgccaacggg
    42661 cgttctcctg ctgttgcatc gccagtggta aaaatccata cacggcgtga atttttcaac
    42721 cgttcacttt tccagataat ttctttggca ggcgtttctg gcgcttgcgg acaatcccat
    42781 cccggttgca gaggcgcttg cggcatttcg agtgcagaaa cagcgtgccc tcgcccgcct
    42841 ttccagcttt gtggattcag cggatcggct attgcctggg gtaatagttt tcgccagcct
    42901 tcacgtaatt cgaggcgatc gggggatggt gcagaaaaaa tgtcatcgcg ttcggtggga
    42961 ataaaacagt agctgccgcg ccagttggca ttgagttgtg tcgtccactg ccagacgttg
    43021 gtgcctgcaa ttcgctgcat cgactggggc tggctgttct gatggtgatc ggtcacacca
    43081 gtgatgtaga cccatacgcg ctttatcgtc gagtattctt cagaaccttg gggatcacgc
    43141 caccagaaag tgacctcaaa catttcgtca ttcagacgct gccattccgg gccatgtttc
    43201 gactgccacc agctctcact tcctactttt aacgccgtca caccataacc ccatgtttac
    43261 tgtgcaattt ttcattgatt gcagaaatat attgataata ttattgataa ctatttgcat
    43321 ttgcaatagc gtaatggcgc gccgtgggaa gcgcggacat taattaacca actgcactgc
    43381 gtgtctttca ggatcaaagg ttttcgcggt agcgggatgc gtcgtattga tgacgaccat
    43441 gcccgacagt tgcaattcgt ggcaaaaatg caggaataaa acaatgaaca agaagattca
    43501 ttccctggcc ttgttggtca atctggggat ttatggggta gcgcaggcac aagagccgac
    43561 cgatactcct gtttcacatg acgatactat tgtcgttacc gccgccgagc agaacttgca
    43621 ggcacctggc gtttcgacca tcaccgcaga tgaaatccgc aaaaacccag ttgcccgcga
    43681 tgtgtcggag atcatccgta ccatgccagg cgttaacctg accggtaact ccaccagtgg
    43741 tcagcgtggt aataaccgcc agattgatat tcgcggcatg ggtccggaaa acacgctgat
    43801 tttgattgac ggcaagccag taagcagccg taattcggtg cgtcagggct ggcgtggtga
    43861 gcgcgatacc cgtggtgata cctcctgggt gccacctgaa atgattgaac gtattgaagt
    43921 tctgcgtggt ccggcagctg cgcgttatgg caacggcgcg gcgggcggcg tggttaacat
    43981 cattaccaaa aaaggcagtg gtgagtggca cggctcctgg gatgcttatt tcaatgcgcc
    44041 agaacataaa gaggaaggtg ccaccaaacg taccaacttc agcctgaccg gtccgctggg
    44101 cgacgaattc agcttccgct tgtatggcaa cctcgacaaa acccaggctg acgcgtggga
    44161 tatcaaccag ggccatcagt ccgcgcgtgc cggaacgtat gtcacgacgt taccagccgg
    44221 gcgcgaaggg gtgatcaaca aagatattaa tggcgtggtg cgctgggact tcgcaccatt
    44281 gcaatcgctg gaactggaag cgggttacag ccgccagggt aacctgtatg cgggcgatac
    44341 ccagaacacc aactctgacg cttacactcg ctcgaaatat ggcgatgaaa ccaaccgcct
    44401 gtatcgccag aactacgcgc tgacctggaa cggtggctgg gataacggcg tgaccaccag
    44461 caactgggtg cagtatgaac acacccgtaa ctcgcgtatt ccggaaggtc tggcgggcgg
    44521 taccgaaggg aaatttaacg aaaaagcgac acaggatttc gtcgatatcg atcttgatga
    44581 cgtgatgctg cacagcgaag ttaacctgcc gattgatttc ctcgttaacc agacgctgac
    44641 gctgggtacg gagtggaatc agcaacggat gaaggacttg agttccaata cccaggcgct
    44701 gaccggggcg aacaccggcg gcgctattga tggtgtgagt gccaccgacc gtagcccgta
    44761 ttcaaaagca gaaattttct cgctgtttgc cgaaaacaac atggagctga ctgacagcac
    44821 catcgtaacg ccggggctgc gtttcgatca tcacagtatt gtcggcaata actggagccc
    44881 ggcgctgaac atatcgcaag gtttaggcga tgacttcacg ctcaaaatgg gcattgcccg
    44941 tgcttataaa gcaccgagcc tgtaccagac taacccgaac tacattctct acagtaaagg
    45001 tcagggttgc tatgccagcg cgggcggctg ctatctgcaa ggtaacgatg acctgaaagc
    45061 agaaaccagc atcaacaaag agattggtct ggagttcaaa cgcgacggct ggctggcggg
    45121 cgtcacctgg ttccgtaacg attatcgcaa taagattgaa gcgggctatg tggctgtagg
    45181 acaaaacgca gtcggcaccg atctctatca gtgggataac gtgccgaaag cagtggttga
    45241 aggtctggaa ggatcgttaa acgtaccggt tagcgaaacg gtgatgtgga ccaataacat
    45301 cacttatatg ctgaagagta aaaacaaaac cacgggcgac cgtttgtcga tcatcccgga
    45361 gtatacgttg aactcaacgc tgagctggca ggcacgagaa gatttgtcga tgcaaacgac
    45421 cttcacctgg tacggtaagc agcagccgaa gaagtacaac tataaaggtc agccagcggt
    45481 tggcccggaa accaaagaaa tcagtcctta cagcattgtg ggtctgagcg cgacctggga
    45541 tgtgacgaag aatgtcagtc tgaccggcgg cgtggacaac ctgttcgaca aacgtttgtg
    45601 gcgtgcgggt aatgcccaga ccacgggcga tctggcaggg gccaactata tcgcgggtgc
    45661 cggggcgtat acctataacg agccgggacg tacgtggtac atgagcgtaa acactcactt
    45721 ctgatgctaa cgtcagattg ttgacaaagt gcgcgtcgtt catgccggat gcggcgtgaa
    45781 cgccttatcc ggcctacaaa aatcttgcca attcaatata ttgcaggacc atgtaggcct
    45841 gataagcgta gcgcatcagg cagtttagcg tttgtcatca gtctctaata tggtcgacat
    45901 gaaaactacg catacctccc tcccctttgc cggacatacg ctgcattttg ttgagttcga
    45961 tccggcgaat ttttgtgagc aggatttact ctggctgccg cattacgcgc aactgcaaca
    46021 cgctggacgg aagcgcaaag ccgaacattt agccgggcgg atcgctgcaa tttatgcgct
    46081 gcgggaatat ggctataaat gtgtgcccgc aatcggcgag ctacgccaac cggtgtggcc
    46141 tgcggaggta tacggcagta ttagccactg cggggctacg gcattggccg tggtttcccg
    46201 tcaaccgatt ggcgttgata tcgaagaaat tttttctgcg caaacagcga ccgaattgac
    46261 agacaacatt attacaccag cagaacacga gcgactcgca gactgcggtt tagccttttc
    46321 tctggcgctg acactggcat tttccgccaa agagagcgca tttaaggcaa gtgagatcca
    46381 aactgatgca ggttttctgg actatcagat aattagctgg aataaacagc aggtcatcat
    46441 tcatcgtgag aatgagatgt ttgctgtgca ctggcagata aaagaaaaaa tagtcataac
    46501 tctgtgccaa cacgattaat tgacaacatc tggtacgatt cgcccgcagc catcactgac
    46561 cgcgggcgaa agtgtaaagc aggtgcctta ccactctgac ctgacaaccg gatatgcggg
    46621 gattgctccc cgcacaacgg ctacttcttc ggttcgtaag cgagaacagc cttaaactca
    46681 atattacgtt cctttacggt gaactcacac agcgagtctc cgaccagaag cgtaaatccc
    46741 agtaccgtca aacacagcac tatgactgcc acaagggcat atttcgtcag catgtttata
    46801 ttgcctccat gcgaagaagg gactaccatc cgagttgttg aggctcggag tggcagcccc
    46861 aggattgata gaaatatctc ctggggcttc atctttccag acctcagagt taacctgaaa
    46921 ccggaaagct tcaggcaccc gccgttatct tacccttcct caacaaaata gctgtttatt
    46981 tatacagtga atcctgtttc ggacttctgt cggcaaaact catcattgct cttaaaacga
    47041 aatcgcccgc agccatcact gaccgcgggc gaaagtgtaa agcaggtgcc ttaccatcct
    47101 gacctgacaa ccggatatgc ggggattgct ccccgcacaa cggctacttc ttcggttcgt
    47161 aagcgagaac aaccttaaac tcaatattac gttcctttac ggtgaactca cacagcgaat
    47221 ccccgaccag aagcgtaaat cccagcaccg ttaaacacag cactatgact gccgcaaggg
    47281 catatttcgt cagcatgttt atattgcctc catgcgaaga agggactacc atccaaattg
    47341 ttcaggtttg ggtaggtagc cccagggttg atagaaatat cgtcctgggg cttcatcttt
    47401 ccagacctca gagtaaacct gaaaccggaa agcttcaggc acccgcagtt atcttaccct
    47461 tgcttagcaa aatagctgtt tatttataca gtaagtcctg tttcggactt ctcactcccc
    47521 atttgatcaa ctgaagctga acccgttttt ttctgcatgc ctcaatcgtc aaaattcttc
    47581 gccaccagcc agccgtgcca taacttgtca cattgcaaaa gtagccaaat tgcttcagtc
    47641 accatcacca aaaaaagaaa cattccagaa cttccgcatc tcgcccagcc gctccgactt
    47701 ctatactgaa tagaaaacgc caacttaaga gaaacctatg ccattacccg attttcatgt
    47761 ttctgaacct tttaccctcg gtattgaact ggaaatgcag gtggttaatc cgccgggcta
    47821 tgacttaagc caggactctt caatgctgat tgacgcggtt aaaaatgaga tcacggccgg
    47881 agaggtaaag cacgatatca ccgaaagtat gctggagctg gcgacggatg tttgccgtga
    47941 tatcaaccag gctgccgggc agttttcagc gatgcagaaa gtcgtattgc aggcagccgc
    48001 agaccatcat ctggaaattt gcggcggtgg cacgcacccg tttcagaaat ggcagcgtca
    48061 ggaggtatgc gacaacgaac gctatcaacg aacgctggaa aactttggct atctcatcca
    48121 gcaggcgacc gtttttggtc agcatgtcca tgttggctgc gccagtggcg atgacgccat
    48181 ttatttgctg cacggcctgt cacggtttgt gccgcacttc atcgcccttt ccgccgcgtc
    48241 gccgtatatg cagggaacgg atacgcgttt tgcctcctca cgaccgaata ttttttccgc
    48301 ctttcccgat aatggcccga tgccgtgggt cagtaactgg caacaatttg aagccctgtt
    48361 tcgctgcctg agttacacca cgatgatcga cagcattaaa gatctgcact gggatattcg
    48421 ccccagtcct cattttggca cggtggaggt tcgggtgatg gataccccgt taacccttag
    48481 ccacgcggta aatatggcgg gattaattca ggccaccgcc cactggttac tgacggaacg
    48541 cccgtttaaa catcaggaga aagattacct gctgtataaa ttcaaccgtt tccaggcctg
    48601 ccgctatggg ctggaaggcg tcattaccga tccgcacact ggcgatcgtc gaccgctaac
    48661 ggaagatacc ttgcgattgc tggaaaaaat cgccccttcc gcacataaaa tgggtgcatc
    48721 gagcgcgatt gaggccctgc atcgccaggt cgtcagcggt ctgaatgaag cgcagctgat
    48781 gcgcgatttc gtcgccgatg gtggctcgct gattgggctg gtgaaaaagc attgtgagat
    48841 ctgggccggt gactaagtag ggaattgcct tacagaagaa tatccctgac aatggtgttt
    48901 taacttacat ttaacaatgt tatgaaacac cctttagaaa ccttgactac cgcagcaggc
    48961 attttgctga tggctttcct ctcttgcctg ctgctgcccg cccccgcact ggggctgacg
    49021 ctggcacaaa aactggtgac catgttccat ctgatggatc ttagccagct ttacacttta
    49081 ttgttttgtc tgtggttttt agtgctgggc gctattgagt attttgttct gcgctttatc
    49141 tggcgacgct ggttctcgct ggcggattaa acgtcgatta tcgccgtact tcgcggcata
    49201 ctttgcttat tctccttcgc ctaaaggaac gtttatggat aagcaatcac tgcacgaaac
    49261 ggcgaaacgc ctggcccttg agttaccctt tgtcgagctt tgctggcctt ttggcccgga
    49321 gttcgatgtt tttaaaattg gcggcaaaat ttttatgctg tcgtcggagc tgcgcggcgt
    49381 cccctttatc aatctgaagt ccgatccaca aaaatccctg ttaaatcagc agatataccc
    49441 gagcattaag ccagggtatc acatgaataa aaagcactgg atttcggtgt atcccggcga
    49501 ggaaatctcc gaagcgttaa ttcgcgatct gatcaacgat tcgtggaatc tggtggttga
    49561 tggtctggct aaacgcgatc aaaaaagagt gcgtccaggc taaagcggaa atctatagcg
    49621 catttttctc gcttaccatt tctcgttgaa ccttgtaatc tgctggcacg caaaattact
    49681 ttcacatgga gtctttatgg atatcatttc tgtcgcctta aagcgtcatt ccactaaggc
    49741 atttgatgcc agtaaaaaac ttaccccgga acaggccgag cagatcaaaa ctctcctgca
    49801 atacagccca tccagcacca actcccagcc gtggcatttt attgttgcca gcacggaaga
    49861 aggtaaagcg cgtgttgcca aatccgctgc cggtaattat gtgttcaacg aacgtaaaat
    49921 acttgatgcc tcgcacgtcg tggtgttctg tgcaaaaacc gcgatggacg atgcctggct
    49981 gaagctggtt gttgaccagg aagatgctga tggccgcttt gccacgccgg aagcgaaagc
    50041 tgcgaacgat aaaggtcgca agttcttcgc tgatatgcac cgtaaagatc tgcatgatga
    50101 tgcagagtgg atggcaaaac aggtttatct caacgtcggt aacttcctgc tcggcgtggc
    50161 ggcgctgggt ctggacgcgg tacccatcga aggttttgac gccgccatcc tcgatgcaga
    50221 atttggtctg aaagagaaag gctacaccag tctggtggtt gttccggtag gtcatcacag
    50281 cgttgaagat tttaacgcta cgctgccgaa atctcgtctg ccgcaaaaca tcaccttaac
    50341 cgaagtgtaa ttctctcttg ccgggcatct gcccggctat ttcccctcag attctcctga
    50401 tttgcataac cctgtttcag ccgtcatcat aggctgctgt tgtataaagg agacgttatg
    50461 caggatttaa tatcccaggt tgaagattta gcgggtattg agatcgatca caccacctcg
    50521 atggtgatga ttttcggtat tatttttctg accgccgtcg tggtgcatat tattttgcat
    50581 tgggtggtac tgcggacctt cgaaaaacgt gccatcgcca gttcacggct ttggttgcaa
    50641 atcattaccc agaataaact cttccaccgt ttagctttta ccctgcaggg gattatcgtc
    50701 aatattcagg cggtattctg gctgcaaaaa ggcaccgaag cggcagatat tctgactacc
    50761 tgcgcgcagt tgtggatcat gatgtatgcg ctgctttcag tcttctcgtt gctggatgtt
    50821 attttgaatc tggcgcagaa attcccggcg gcatctcagt taccgctgaa agggatattt
    50881 caggggatta aactgatcgg cgcaatcctg gtcggcattt tgatgatctc gctgctgatt
    50941 ggtcagtcgc cagcgattct gatcagcggt cttggtgcaa tggctgccgt gctgatgttg
    51001 gtttttaaag atccgattct tggtctggtg gcaggtattc agctttccgc gaacgatatg
    51061 ctgaaactgg gcgactggct ggagatgccg aaatacggcg cggatggcgc ggtgatcgat
    51121 attgggttaa ccaccgtcaa agtgcgtaac tgggacaata ccattaccac tattcccacc
    51181 tggtctctgg tttctgactc ctttaaaaac tggagcggga tgtcagcatc tggcgggcga
    51241 cgtattaagc gcagtatcag tattgatgtc accagtattc gttttcttga tgaagacgaa
    51301 atgcaacgtc tgaataaagc gcacttgtta aaaccttatt taaccagccg ccatcaggaa
    51361 attaatgagt ggaatcgcca gcaaggttct acggagtcga tattaaacct gcgccgaatg
    51421 accaatattg gaacctttcg tgcctatctg aacgaatatc tgcgtaacca tccgcggatt
    51481 cgtaaagata tgaccttaat ggtacgccaa ctggctccag gtgataacgg tttaccgctc
    51541 gagatctacg cgtttactaa caccgtggtg tggctggaat atgaaagcat tcaggctgat
    51601 atattcgatc acatatttgc gattgtcgaa gagtttggtc tgcgacttca tcagtcgcca
    51661 accggcaatg atattcgctc tctggcgggt gcatttaagc agtaattaaa aaaaccgctc
    51721 tcatcgaatg gatgagagcg gacatcgttt tgtcggatgt agcgtgaatg ccttatttcc
    51781 gacgcagcgt tttaaatgcc acaaacagga atacaatcca caccggcagc aggatcgctg
    51841 acaagcgcat atcatccatc gtgcacatca gcagcaaaat catgccgagg aaggcaatgc
    51901 aaagatagtt gccgaacgga tagagcagcg ccttaaactg tgtttcacgc ccctgacgtc
    51961 gcatcgctgc acgaaaacgc agatgcgcca gacagatcat aatccagttc aacagcagcg
    52021 ttgctaccac cagcgccatc agcagaccaa acgctttttg cggcagcaga tagttgatta
    52081 ataccaccag cgaagtgatc gctccggaaa gcatcagcga gttaatcggc acaccgcgac
    52141 ggctgacgcg agtcaaaaac ttcggcgcat taccctgcac agaaaggcca aacagcatgc
    52201 ggctgttaga gtaaaccccg ctgttataca ctgacagcga tgctaccaga atgacgaagt
    52261 tcagcgcaga agctaccacg ttgctgtcga gattatggaa aatcatcaca aacgggctac
    52321 tgttggattt cacttccacc cacggataga gcgccagtaa aaccaccagt gaaccgatgt
    52381 aaaacagcag gatgcgatac accacctgat ttaccgcttt tggaatgctt ttttccggat
    52441 cgcgcgcttc agcggcagta atcccaatca gctccagacc gccgaaggag aacataatta
    52501 ccgccagcga caaaatcagc ccattccagc cggtggcgaa gaaaccaccg tagcgccaga
    52561 ggttgtcgat actggctttc tcgccgccgt gaccagaaaa cagcagccac aggccaaagc
    52621 cgatcatacc gatgatcgcc agcactttaa tcagcgcaaa ccagaactcg gtttcaccat
    52681 ataagcgcac gttcaccagg ttaacggcgt tgatgataat aaagaaggcg gcagcccaaa
    52741 tccacgttgg aacatccggg aaccagtact gcatatagat gcccgcagcg gtcagctctg
    52801 ccattcccac cagcacgaac attacccagt agttccagcc agagaggaag cccgcaaacg
    52861 gtccccagta tttataggca aagtgggcaa atgaaccgga taccggctcc tcaaccacca
    52921 tttcgccaag ctggcgcata atcaggaaag cgatgatccc ggcgacgccg tagcccagca
    52981 atacagccgg acccgccatc tgaatcgccg ggccaatgcc aagaaacaga ccagtaccaa
    53041 ttgcgccacc caacgcaatc agttgaatat gacggttatg taatccgcga tgaagcgtcg
    53101 gctcttgatt cgacgcagta tcttccgata cggttgacgc gtttttcacg cctttcccct
    53161 gtgtgtcttt tttgttgagg ggcacctttt aacatttagt gcccatcgtc gcaagacaca
    53221 atccacacgg ttaaacgggg tatcctgctt ttatttccgt acccgatgtc ggtgcagcca
    53281 catcagctta tacgccgccg ggataataaa cagcgacagc aaaggtgcgg tgatcatgcc
    53341 gccaatcatc ggtgcggcaa tccggctcat cacctctgaa ccagcccccg ttccccacag
    53401 aatcggcagc agaccggcga taatcaccgc caccgtcatc gctttcgggc gcacgcgcag
    53461 gaccgcgccg tgatataacg cctcatccag cttctgctcg ctgaatgttt gtggattatt
    53521 caacgacggc acggcctcta tggcgtgacg taaatacatc agcatcacca cgccaaattc
    53581 ggcggcgacc ccggcgaggg cgataaagcc agtgcccgtc gccacggaaa gatgaaagcc
    53641 catccaccac agcaaccaga tgccgcccac cagcgcaaac ggtacgctgc tgataatcag
    53701 caacgcttcg cccacccgac ggaacgccag atacaacagc acgaagataa tcatcaacgt
    53761 catcggcacc atgagtttaa gcttatggtt ggcgcgctcc agtagctcga actgcccgga
    53821 gaatgccacg ctggtgcccg gttttaactg cactttttca gctatcgctt tttgcaaatc
    53881 gtgaaccacc gacaccatgt cacgatcgcg ggcatcgata taaatccagc tcgtcgggcg
    53941 cgcattctcg gttttcagca tcgacggtcc ggtagagact ttaatgtcgg ccacgtctgc
    54001 cagggtgatt tgctgcttca tcggcgtcag gatcggcagc tggcgcagtg cctgcggact
    54061 atcgcgccag ctttgcggat aacgcagatt aattggataa cgggcaatcc cttccaccgt
    54121 ttcgccaacc atcgccccgc ccaccgcaga agtcacaaac aactgcacat ccgccaccgt
    54181 cataccgtaa cgtgcggctt tttcacggtt aatctcaacg ttgatatagc gcccaccttc
    54241 cagccgctcg gcaagcgcag aagctacgcc tggcaccgtt cgcgctactt cttcaatttg
    54301 ctcagccatc gcgtcgatat ccgccagcac agtgccggaa actttaatgc cgatggggct
    54361 tttaatgccg gttgagagca tatcgatacg gttacgaatt ggcggcaccc acagattcgc
    54421 cagccccggc agccgcacgg tgttatccag ttcctcaatg attttgtcca tcgtcatgcc
    54481 tggccgccac tgctcctgcg gcttaagctg gatggtcgtt tctaccatct ccagcggagc
    54541 agaatcggtg gcggtttccg ctttcccggt tttgccaaat acccgcgcca cttcaggtac
    54601 gctcataatt agcttgtcgg ttttttgcag catactcgcc gcctctgctg cggaaatccc
    54661 cggcagcgtc gatggcatat acaacaagtc gccttcattg atctgcggta aaaattcccc
    54721 gccaacttta ttgagcggcc agagaaccgt cagcaccgaa agcgccgcca ccagcagcgt
    54781 ggttttcggc cagtgcagta ctttcagcaa cagcggatga taaacacgaa tcaaaaagcg
    54841 attgagcggg ttactgcttt ccggcggaat tttgccacgg atccagtagc ccatcaggat
    54901 cgggatcact acgatcgcca gcagcgccgc acccgccatc gcatacgttt tggtgaacgc
    54961 caacgggcca aacagacgcc cttcctgccc ttccagggtg aagatcggga taaacgacaa
    55021 cgtgataatc agcagactga taaatagcgc cggccccact tcaacagacg catcggtgat
    55081 cacctgccag cgcgttttat tatccagcgt ggcgtcagga tgctggtgct gccactcttc
    55141 cagccgttta tgtgcatttt cgatcatgac gatagcggca tcgaccatcg ccccgacggc
    55201 aatcgcaatg ccacccaacg acataatatt ggcattcagt ccctggaagt gcatgacaat
    55261 aaaagcaata cacaacccca gcggcaacga aataatcgcc accagcgccg agcgcacatg
    55321 ccagagaaac agcgcacaga ctaccgccac cacaataaac tcttccagca acttgccgct
    55381 gaggttgtcg atggcgcggt caatgagctg gctgcgatcg tatgttgtaa ctatctccac
    55441 gccttccggc agactacttt tcagcgtttc cagtttgtcc ttcacggcgg cgatcacttc
    55501 tcgggcgttt ttgccggatc gcaggatcac caccccgccc gccacttcgc cttcgccgtt
    55561 tagttcggca atgccccggc gcatctccgg gccaatctgg accttcgcaa catcgcgcag
    55621 ataaacgggc acgccatttt cactggcttt taaaacgatg tgattaaagt cgtcgagcgt
    55681 ttgcagatag ccgctggcgc gcaccatata ttccgcttcc gccagttcga tcgacgaacc
    55741 gcccgcttcc tggtttgaag catccagcgc gctttttact tcggcgagac tgatgccata
    55801 ctgcgccagg cgctggggat cgataaccac ctgatactct ttcaccacac cgcccaccga
    55861 cgccacttcc gcaacgtcag ggatggtttt cagctcatat ttgagaaacc agtcctgtaa
    55921 tgagcgtaaa tcggccagat cgtgcttacc gctgcgatcc accagtgcat attcatagat
    55981 ccagccaaca cccgtggcat ctggccccag ctcggcgctg actcccgcag gcagcttacc
    56041 ctgtacctgg ttgaggtact ccagcacccg cgaacgcgcc cagtacggat cggtgccatc
    56101 ttcgaaaatg acatacacat aagagtcgcc aaactgtgag aaaccgcgca cagtcttcgc
    56161 gccaggcacc gacaacatgg tggtggttag cggataagtc acctgatttt caacgatttg
    56221 tggtgcctga ccgggatagc tggttttaat aataacctgc acatcggaga gatccggcag
    56281 cgcatccact ggcgtattaa tgatggtcca ggtgccccag atgctcagaa acaacgcgcc
    56341 catcagcacc aaaaaacggt tcgccaccga gcgacgaata atccattcaa tcattggtta
    56401 ttccctcaat gcgcatgggt agcactttca gagcgcatcc gctccagtgc gccagaaata
    56461 ttggcttcgg aatcaatcag gaacaggccg ctggaaacca ccttttcacc ttccgccaga
    56521 ccagagcgta atgcggtgac gccttgcgat gcctggaaaa cagcaacgcg tttcggtaca
    56581 aagcgcccgt cggcatcaac ggtaatcacc cgctgttcgc tgccggtatc aatcagcgct
    56641 tgtgacggaa tgagcagcat cggttcgctg gcggtgttga gttgcaacca ggcgttcatg
    56701 cccggtttta gcgcctcgtc ggcgttgtcg acttccagac gcagctgcag cgtgcgggtc
    56761 gcggcatcca cgccaggtag cagcgtccat ttgcggatgg tgagtgtttt atccggtcgc
    56821 gccggaacgg tgagggtaaa ctgcgaggca tctttcacca gccaggcgat agactccggg
    56881 atcgcagcag tgacccacac cgggtccata ccctgaattt tcgctaccac gttatctttg
    56941 gcgatattca ttcccgcgcg cagatcaaac gcggtgatca cgccatcaat gggcgctttg
    57001 agcgtaaagc gagtctggat tttttgcgtg gcgatcaggc ggcgaatatc cgcctccggc
    57061 attcccgcca gtcgcagccg ctcaagaatg ccttcagtct gggtcgccgt accgccggtt
    57121 tcgcgcagca gtaaatactc actctgcgct tccacccagt caggaatggt caggtcgaga
    57181 agcggtgtgc ccttttgtac tttatcgccc acggtaagcg gatacacctt gtcgataaac
    57241 ccggcagcgc gagcctgcac aatggcatac tgatactcgt tgtaactgac attcgccggg
    57301 aaactctggg caaaagtcag cggcccgcgc gtgacggtag ccgttttcac ccccagattc
    57361 tgcgtctgag tcgggtcaat gcgcacacca gacgcagaac tctcttcatc ggcatatttc
    57421 ggcaccagat ccatatccat aaacggcgat ttacctggtt tatcgaaccg cgtattgggg
    57481 tacatcgggt cgtaccagaa taagatttta cgttctgcgg tcgacgtttt ttctgcgggt
    57541 ggttcagcct ttgcaaacca ggtaaaacct gccgcagaaa taataccgcc cgcgatcatg
    57601 ctgccgataa taagcgcgat ttttttcatc tcattaaacc tgggttactg gctgacttta
    57661 atatcctgta ataaagaaag gttgccctgc tggacaaaat taaacgccac tttgtcgcca
    57721 gttttaattt cactcatttt cgtctgcgga gtgatggtaa agcgcatggt catctccggc
    57781 cagttcacgg cagcaatcgg atcgtgatgg atggtgattt ttttgctttc cagatcaata
    57841 ccctttacca cgccagtggc gctaataacc tgcggttgta cttcgctcat ggtttcatga
    57901 tgatgttcgt tagcctgggc attaaagcca ataacggtaa acagactgaa cattgcgact
    57961 tgcagtgctt ttttcattta ttctctcctg gagttaaaaa ttattgctgc caaccgcccc
    58021 ctaaggcggt atacaaagaa atttcgttaa cctgacgggc ataattcagg tcgagtaaag
    58081 tttgtcgggt tgcaaataaa gaacgctcgg catccagcac ttccagataa cttaccgcgc
    58141 cgtgctgata taatgcccgc gcccgttgca aagtaatttg cagcgacgcc agataacgct
    58201 gctgggcgct gatttgatcg ttcaggcttt gacgtaatgc cagcgcatct gccacttctt
    58261 taaaggcgtt ctggattttc tgttcataat tcactaccga ctgctgctgg cgaatttcgg
    58321 cgatatccag attggcttgg ttgcgtccgg cattaaaaat ggggatctca attttaggaa
    58381 taaaattcca catcccgctg ctagcgttaa ataatgaaga cagatcgctg ctggcggttg
    58441 atattccgct ggtcaggctg atagacggga aaaatgccgc acgcgcagcg ccaatattgg
    58501 cattagccgc cattaacgcg tgttcagctt ccataatatc cgggcgctgc aataagattt
    58561 gcgacgacaa tcccgccggt aatttaacgc tttgcaggct gtcgctgttt actgtctgcg
    58621 cttgcggcag cttgccgtag cttcccaata acagttgcaa tgcattattc gcctgcgcca
    58681 gttccccctg acgtttagcg atgtcgctgc gggtactttc tatcaccccg cgagcctgtt
    58741 ccagcgccag aacattactg ctacctgtca acagttgttt ttcgacaaac gcatatgact
    58801 gctgataatt acgcagcgtt tcttcggcta tttgcaattg cgcatacgcc agttgctgat
    58861 tgaaatagct ttgcgcgaca ttagaaacca gcagaatatg caccgcgcgc tgagcttcct
    58921 cagtggctaa ataattttgt cgctcggctt cgctcatgtt ctttaagcga ccgaaaaaat
    58981 cgaggtcaaa gctggcgtta aggccggtcg aaaactcccg tgtcgtggcg gtattccctt
    59041 taagattacc gctccagctg ccgctgccct cgccattgag ctgtgggtag cggtcggcat
    59101 cggtcagacg atattgcgcc cgtgcctcct gcactttcag cgtcgccatg cgcaaatccc
    59161 gattattcac cagcgcctcg ctaatcagcg tcttcacctg attatcaaca aaaaaggtgc
    59221 gccagcccgc gttctgatag ttatctgctg cgttaaccag gccgttctgg ctgagtgaga
    59281 actgctgcgg cacgggcatt gccggacgct gataatccgg tgccagtgaa caaccggtta
    59341 gcgcaagggc cacacaaaat ggcagaagtt tacaaggaga cataggctca taatttctgg
    59401 tgattttatg ccgccaactt tactcgccag gctctgattt tccggtgaca gaaaaatgac
    59461 aaaattgtca ttttgccaat aagcgattgc catctgatcc cgctactcta gaattgcccg
    59521 ggcaacatgc ggaggaaata tgaaactgtt gattgtcgaa gatgaaaaga aaaccggaga
    59581 atacttgacc aaagggttaa ccgaagccgg ttttgtggtc gatttggccg acaacgggtt
    59641 gaatggctac catctggcga tgaccggtga ttatgatctg ataatcctcg atattatgct
    59701 gccggacgtg aacggctggg atatcgtgcg catgttgcgt tccgccaata aagggatgcc
    59761 gattctgttg cttaccgcgc ttggcaccat tgaacatcgc gtcaaggggc tggagttggg
    59821 ggcggatgac tatctggtga agccgttcgc ttttgctgaa ctgctggcgc gggtgcgcac
    59881 tctcctgcgg cgcggggcgg cggtgattat cgaaagtcag tttcaggttg ccgatctgat
    59941 ggtcgatctc gtcagccgca aagtcacccg cagcggcacg cgcatcactc tgaccagtaa
    60001 agagtttact ctgctggagt ttttcctccg ccatcagggc gaagtgctgc cccgctcgct
    60061 tatcgcctcg caggtgtggg acatgaattt cgacagcgac actaacgcca ttgatgtagc
    60121 ggtgaagcgg ctgcgcggca aaatcgacaa cgactttgag ccaaagctaa ttcagaccgt
    60181 gcgcggcgtg ggttacatgc ttgaggtgcc ggatggtcag taagccattt cagcgcccgt
    60241 tttcgctggc aacccgcctg acctttttta tcagcctggc caccatcgca gcgtttttcg
    60301 cctttgcatg gatcatgatc cactcagtaa aagtgcattt tgccgagcag gatattaatg
    60361 atttaaaaga aattagcgcc acgcttgaac gggtacttaa tcatcctgac gagacgcaag
    60421 cccgacgctt aatgacgctg gaagatatcg tcagtggtta ttccaacgtg ttgatctccc
    60481 tggcagatag ccatggtaaa acggtgtatc actcccccgg tgcgccggat atccgcgagt
    60541 ttacgcgtga cgccataccc gataaagacg cgcggggcgg cgaggtgtat ctcctttccg
    60601 gcccgacgat tatgatgcca gggcatggtc acgggcatat ggaacacagc aactggcgga
    60661 tgattaactt gtcggttggc ccgttggtgg acggcaaacc gatttatacg ctctacatcg
    60721 cgctttcgat cgattttcat cttcattaca taaatgattt gatgaataaa cttattatga
    60781 ccgcatcgat catcagcatc ctgatcgtct ttatcgtgct attggcggta cataaaggtc
    60841 acgcgccgat ccgcagcgtc agccgtcaaa tccagaatat tacctcgaaa gatctcgacg
    60901 ttcgccttga cccgcagacc gtgcccattg agctggaaca gctggtactg tcgttcaacc
    60961 atatgatcga gcgtattgag gatgtcttta cccgccagtc caatttctca gcggatatcg
    61021 ctcacgaaat tcgcacgccg attaccaatc tcatcacgca aacggaaatc gccctcagcc
    61081 agtctcgcag ccagaaggag ctggaagatg tgctctactc taatctcgaa gagctgacgc
    61141 gaatggcgaa aatggtcagc gatatgctgt ttctcgctca ggccgataac aaccagctaa
    61201 tccccgaaaa gaaaatgctc aacctggcgg atgaagtcgg caaagtgttc gattttttcg
    61261 aggcgttagc ggaagatcgc ggcgtggagt tgcgatttgt tggcgacgaa tgtcaggttg
    61321 cgggcgatcc gctgatgctg cgtcgggcgt taagcaacct gctttctaat gccctgcgtt
    61381 atacgccgcc cggagaggca attgtagtgc gctgccagac ggtcgatcac caggtgcaag
    61441 ttaccgtcga aaaccccggt acgcccattg cgcccgagca cttaccgcga ttgtttgacc
    61501 gtttctaccg cgttgaccct tcccgccagc gaaaaggcga aggtagcggc attgggctgg
    61561 cgatagtgaa atcgattgtt gtcgcgcata aaggcacggt tgcagtaacg tcagatgcgc
    61621 gggggacaag gtttgtgatt atgctgccgg agagagagtg attattaagt tcaaattcag
    61681 ggcgtggtgc atcacctcct ggtattgttg atcaacaaat tagagaaaaa cttattaaac
    61741 atatgaaata tcgaaggctt ttatttttca aagtttcacg agatgtttgt atatgaaact
    61801 tagttaaatc tgtgtttctt ccaattgtag atcacaatgc cctttctaaa ttttcatcgt
    61861 tataaacaag ccatctatca tataaagcaa tgaataattt aat
//
LOCUS       DAZUDJ010000022        61370 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.022, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000022 DAZUDJ010000000
VERSION     DAZUDJ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 61370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61370
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.022"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..270
                     /locus_tag="ACHY1N_001924"
     CDS             <1..270
                     /locus_tag="ACHY1N_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004842 - ubiquitin-protein transferase
                     activity [Evidence IEA];
                     GO_process: GO:0044403 - biological process involved in
                     symbiotic interaction [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector NleG family protein"
                     /protein_id="HFS4044245.1"
                     /translation="CLFRPDSNHFSCPESFLTCPITLDTPETGVFMRNSRGAEICSLY
                     DKDALVQLVETGGAHPLSREPITESMIMRKDECHFDTKREAFCCK"
     gene            352..993
                     /locus_tag="ACHY1N_001925"
     CDS             352..993
                     /locus_tag="ACHY1N_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1076 domain-containing protein"
                     /protein_id="HFS4044246.1"
                     /translation="MPVDLTPYILPGVSFLSDIPQETLSEIRNQTIRGEAQIRLGELM
                     VSIRPMQVNGYFMGSLNQDGLSNDNIQIGLQYIEHIERTLNHGSLTSREVTVLREIEM
                     LENMDLLSNYQLEELLDKIEVCAFNVEHAQLQVPESLRTCPVTLCEPEDGVFMRNSMN
                     SNVCMLYDKMALIHLVKTRAAHPLSRESIAVSMIVGRDNCAFDPDRGNFVLKN"
     gene            complement(1574..2008)
                     /gene="uspF"
                     /locus_tag="ACHY1N_001926"
     CDS             complement(1574..2008)
                     /gene="uspF"
                     /locus_tag="ACHY1N_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310024.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HFS4044247.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEAEAKIDDAEVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFKLPTDRVHVHVEEGSPKDRILEM
                     AKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
     gene            complement(2149..3282)
                     /gene="ompN"
                     /locus_tag="ACHY1N_001927"
     CDS             complement(2149..3282)
                     /gene="ompN"
                     /locus_tag="ACHY1N_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpN"
                     /protein_id="HFS4044248.1"
                     /translation="MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNSAKDGDQSYARLGFKGETQINDQLTGYGQWEYNIQANNTESSKNQSWTRLAFAGL
                     KFADYGSFDYGRNYGVMYDIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFF
                     GLVNGLNFAVQYQGNNEGASNGQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAY
                     TSSDRTNDQVNHTAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDSDYAVAN
                     KTQNFEVTAQYQFDFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADVGATY
                     YFNKNMSTYVDYKINLLDEDDSFYAANGISTDDIVALGLVYQF"
     gene            complement(3648..7172)
                     /gene="nifJ"
                     /locus_tag="ACHY1N_001928"
     CDS             complement(3648..7172)
                     /gene="nifJ"
                     /locus_tag="ACHY1N_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFS4044249.1"
                     /translation="MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISHIATLKSR
                     VPFIHFFDGFRTSHEINKIVPLADDTILDLMPQAEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYDAVYDHVEQAMNDFSAATGRQYQPFEYYGHPQAERVIILMGSAI
                     GTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRSVAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFAELNAAKPKARF
                     TVGIYDDVTNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEQPIRSAYLISQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSADEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINTVMQMAF
                     FHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHS
                     ANRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     IWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRVRVLRLLDQFADKIPAELLT
                     ALKSDATPEVRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKLPLALDSRPPSVALEETLLHEQRFRRLNSQQPEVAEQL
                     WKDAAADLQKRYDFLAQMAGKAEKSNTD"
     gene            7446..7712
                     /gene="ydbJ"
                     /locus_tag="ACHY1N_001929"
     CDS             7446..7712
                     /gene="ydbJ"
                     /locus_tag="ACHY1N_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HFS4044250.1"
                     /translation="MRAAFWVGCAALLLSACSSEPVQQATAAHVAPGLKASMSSSGEA
                     NCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            complement(7709..8131)
                     /gene="hslJ"
                     /locus_tag="ACHY1N_001930"
     CDS             complement(7709..8131)
                     /gene="hslJ"
                     /locus_tag="ACHY1N_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HFS4044251.1"
                     /translation="MKKVAAFVALSLLMAGCVSNDKIAVTPEQLQHHRFVLESVNGKP
                     VTSDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGELTAKGLAMTRMMCANPQLNELD
                     NTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN"
     gene            complement(8242..9231)
                     /gene="ldhA"
                     /locus_tag="ACHY1N_001931"
     CDS             complement(8242..9231)
                     /gene="ldhA"
                     /locus_tag="ACHY1N_001931"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HFS4044252.1"
                     /translation="MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANG
                     CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDP
                     EAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAML
                     RILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEA
                     AFDQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVI
                     QDDVFRRLSACHNVLFTGHQAFLTAEALTSISQTTLQNLSNLEKGETCPNELV"
     gene            9439..12078
                     /gene="ydbH"
                     /locus_tag="ACHY1N_001932"
     CDS             9439..12078
                     /gene="ydbH"
                     /locus_tag="ACHY1N_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HFS4044253.1"
                     /translation="MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRI
                     ALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLSHPSRWLLNVGTVELDSACLAKL
                     PQTEQSPAAPKTLAQWQSMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGE
                     KVKFQGQLKGQQLTVSELDVVAFENQPPVKLVGEFTMPLVPDGLPVSGHATATLNLPQ
                     EPSLVDAELDWQENSGQLIVLARDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLS
                     GRLGVKVDNWQAGLENALISGRLSVLTQGQAGKGNAVLNFGPGKLSMDNSQLPLQLTG
                     EAKQADLILYARLPAQLSGSLSDPTLTFEPGALLRSKGRVIDSLDIDEIRWPLAGVKV
                     TQRGVDGRLQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATW
                     DVAGKGEWHDSTITLTDLSTGFDQLQYGTMTVEKPRLILDKPVVWVRDAQHPSFSGAL
                     SLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRWDGIRLR
                     GNAWWPKQSLTVFQPLVPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAW
                     MPDNQVNGVDFVLPFRFADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTE
                     EEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNLSSSELVSAVNPKQFAMSGAF
                     SGALPLWLNNEKWIVKDGWLANSGPMTLRLDKDTADAVVKDNMTAGSAINWLRYMEIS
                     RSSTKINLDNLGLLTMQANITGTSRVDGKSGTVNLNYHHEENIFTLWRSLRFGDNLQA
                     WLEQNARLPGNDCPQGKECEEKQ"
     gene            12075..12260
                     /gene="ynbE"
                     /locus_tag="ACHY1N_001933"
     CDS             12075..12260
                     /gene="ynbE"
                     /locus_tag="ACHY1N_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HFS4044254.1"
                     /translation="MKILLAALTSSFMLVGCTPRIEVAAPKEPITINMNVKIEHEIII
                     KADKDVEELLETRSDLF"
     gene            12265..12594
                     /gene="ydbL"
                     /locus_tag="ACHY1N_001934"
     CDS             12265..12594
                     /gene="ydbL"
                     /locus_tag="ACHY1N_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707676.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HFS4044255.1"
                     /translation="MMKKTLLLCAFLVGLVSSNIMALTLDEARTQGRVGETFYGYLVA
                     LKTDAETEKLVTDINAERKASYQQLAKQNNVSVDDIAKLAGQKLVARAKPGEYVQGIN
                     GKWVRKF"
     gene            complement(12766..13671)
                     /gene="feaR"
                     /locus_tag="ACHY1N_001935"
     CDS             complement(12766..13671)
                     /gene="feaR"
                     /locus_tag="ACHY1N_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator FeaR"
                     /protein_id="HFS4044256.1"
                     /translation="MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLETHFAKGL
                     KLSTVTTNGVNLYRTWQEVKGSDDAWFYTVFQLSGQAIMEQDERQVQIGAGDITLLDA
                     SRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMN
                     NPALSETESEAALQAMVCLLRPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEW
                     IAGETGMSVRSLYRMFADKGLVVAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFS
                     DQSHFSTVFKQRFGMTPGEYRRKFR"
     gene            13907..15406
                     /gene="feaB"
                     /locus_tag="ACHY1N_001936"
                     /gene_synonym="maoB"
                     /gene_synonym="padA"
     CDS             13907..15406
                     /gene="feaB"
                     /locus_tag="ACHY1N_001936"
                     /gene_synonym="maoB"
                     /gene_synonym="padA"
                     /EC_number="1.2.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415903.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetaldehyde dehydrogenase"
                     /protein_id="HFS4044257.1"
                     /translation="MTEPHVAVLSQVQQFLDRQHGLYIDGRPGPAQSEKRLAIFDPAT
                     GQEIASTADANEADVDNAVMSAWRAFVSRRWAGRLPAERERILLRFADLVEQHSEELA
                     QLETLEQGKSIAISRAFEVGCTLNWMRYTAGLTTKIAGKTLDLSIPLPQGARYQAWTR
                     KEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELASEAGI
                     PDGVFNVVTGSGAVCGAALTSHPHVAKISFTGSTATGKGIARTAADHLTRVTLELGGK
                     NPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLFDTLVSGFEQAVKSLQ
                     VGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPAGEGYYVAPTLVVN
                     PDAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQNLSQALEYSDRL
                     QAGTVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSVCVRY"
     gene            complement(15464..17737)
                     /gene="tynA"
                     /locus_tag="ACHY1N_001937"
     CDS             complement(15464..17737)
                     /gene="tynA"
                     /locus_tag="ACHY1N_001937"
                     /EC_number="1.4.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415904.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0008131 - primary amine oxidase activity
                     [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_process: GO:0009308 - amine metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primary-amine oxidase"
                     /protein_id="HFS4044258.1"
                     /translation="MGSPSLYSARKTTLALAVALSFAWQAPVFAHGGEAHMVPMDKTL
                     KEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVPVVMKDNKAWVSD
                     TFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLP
                     PDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPTKDAHGMVL
                     LDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVI
                     SYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDSRDRVAPAVK
                     PMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSL
                     GGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP
                     MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENG
                     TIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDV
                     DGENNSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKE
                     NRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEG
                     KYPNRSTHDTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKP
                     WNFFDETPTLGALKKDK"
     gene            complement(17985..20030)
                     /gene="paaZ"
                     /locus_tag="ACHY1N_001938"
     CDS             complement(17985..20030)
                     /gene="paaZ"
                     /locus_tag="ACHY1N_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation bifunctional
                     protein PaaZ"
                     /protein_id="HFS4044259.1"
                     /translation="MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAA
                     RLFAIEKGAPALRAMTFIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEG
                     GIGTLFTYASLGSRELPDDTLWPEDELLPLSKEGGFAARHVLTSKSGVAVHINAFNFP
                     CWGMLEKLAPTWLGGMPAIIKPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDL
                     LDHLDSQDVVTFTGSATTGQMLRVQPNIVAKSIPFTMEADSLNCCVLGEDITPDQPEF
                     ALFIREVVREMTTKAGQKCTAIRRIIVPQTLVNAVSDALVARLQKVVVGDPAQEGVKM
                     GALVNAEQRADVQEKVNTLLAAGCEIRLGGQADLSAAGAFFPPTLLYCPQPDETPAVH
                     ATEAFGPVATLMPAQNQQHALQLACAGGGSLAGTLVTADPQIARQFIADAARTHGRIQ
                     ILNEESAKESTGHGSPLPQLVHGGPGRAGGGEELGGLRAVKHYMQRTAVQGSPTMLAA
                     ISKQWVRGAKVEEDRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSGDHFYAH
                     MDKIAAAESIFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLESLRFIEPVKPGDTI
                     QVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQHGDFVD"
     gene            20315..21244
                     /gene="paaA"
                     /locus_tag="ACHY1N_001939"
     CDS             20315..21244
                     /gene="paaA"
                     /locus_tag="ACHY1N_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097266 - phenylacetyl-CoA 1,2-epoxidase
                     activity [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaA"
                     /protein_id="HFS4044260.1"
                     /translation="MTQEERFEQRIAQETAIEPQDWMPDAYRKTLIRQIGQHAHSEIV
                     GMLPEGNWITRAPTLRRKAILLAKVQDEAGHGLYLYSAAETLGCAREDIYQKMLDGRM
                     KYSSIFNYPTLSWADIGVIGWLVDGAAIVNQVALCRTSYGPYARAMVKICKEESFHQR
                     QGFEACMALAQGSEAQKQMLQDAINRFWWPALMMFGPNDDNSPNSARSLAWKIKRFTN
                     DELRQRFVDNTVPQVEMLGMTVPDPDLHFDTESGHYRFGEIDWQEFNEVINGRGICNQ
                     ERLDAKRKAWKEGTWVREAALAHAQKQHARKVA"
     gene            21256..21543
                     /gene="paaB"
                     /locus_tag="ACHY1N_001940"
     CDS             21256..21543
                     /gene="paaB"
                     /locus_tag="ACHY1N_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaB"
                     /protein_id="HFS4044261.1"
                     /translation="MSNVYWPLYEVFVRGKQGLSHRHVGSLHAADERMALENARDAYT
                     RRSEGCSIWVVKASEIVASQPEERGEFFDPAESKVYRHPTFYTIPDGIEHM"
     gene            21552..22298
                     /gene="paaC"
                     /locus_tag="ACHY1N_001941"
     CDS             21552..22298
                     /gene="paaC"
                     /locus_tag="ACHY1N_001941"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaC"
                     /protein_id="HFS4044262.1"
                     /translation="MNQLTAYTLRLGDNCLVLSQRLGEWCGHAPELEIDLALANIGLD
                     LLGQARNFLSYAAELAGEGDEDTLAFTRDERQFSNLLLVEQPNGNFADTIARQYFIDA
                     WHVALFTRLMESRDPQLAAISAKAIKEARYHLRFSRGWLERLGNGTDVSGQKMQQAIN
                     KLWRFTAELFDADEIDIALSEEGIAVDPRTLRAAWEAEVFAGINEATLNVPQEQAYRT
                     GGKKGLHTEHLGPMLAEMQYLQRVLPGQQW"
     gene            22313..22810
                     /gene="paaD"
                     /locus_tag="ACHY1N_001942"
     CDS             22313..22810
                     /gene="paaD"
                     /locus_tag="ACHY1N_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415909.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaD"
                     /protein_id="HFS4044263.1"
                     /translation="MQRLATIAPPQVHEIWALLSQIPDPEIPVLTITDLGMVRNVTQM
                     GEGWVIGFTPTYSGCPATEHLIGAIREAMTTHGFTPVQVVLQLDPAWTTDWMTPDARE
                     RLRQYGISPPAGHSCHAHLPPEVRCPRCASVHTTLISEFGSTACKALYRCDSCREPFD
                     YFKCI"
     gene            22818..23888
                     /gene="paaE"
                     /locus_tag="ACHY1N_001943"
     CDS             22818..23888
                     /gene="paaE"
                     /locus_tag="ACHY1N_001943"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaE"
                     /protein_id="HFS4044264.1"
                     /translation="MTTFHSLTVAKVEPETRDAVTITFAVPQPLQEAYRFRPGQHLTL
                     KASFDGEELRRCYSICRSYLPGEISVAVKAIEGGRFSRYAREHIRQGMTLEVMVPQGH
                     FGYQPQAERQGRYLAIAAGSGITPMLAIIATTLQTEPESQFTLIYGNRTSQSMMFRQA
                     LADLKDKYPQRLQLLCIFSQETLDSDLLHGRIDGEKLQSLGASLINFRLYDEAFICGP
                     AAMMDETEAALKALGMPDKTIHLERFNTPGTRVKRSVNVQSDGQKVTVRQDGRDREIV
                     LNADDESILDAALRQGADLPYACKGGVCATCKCKVLRGKVAMETNYSLEPDELAAGYV
                     LSCQALPLTSDVVVDFDAKGMA"
     gene            23885..24652
                     /gene="paaF"
                     /locus_tag="ACHY1N_001944"
     CDS             23885..24652
                     /gene="paaF"
                     /locus_tag="ACHY1N_001944"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dehydroadipyl-CoA hydratase PaaF"
                     /protein_id="HFS4044265.1"
                     /translation="MSELIVSRQQQVLLLTLNRPAARNALNNALLTQLVNELEAAATD
                     SSISVCVITGNARFFAAGADLNEMAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGY
                     ALGAGCELALLCDVVVAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSG
                     ESITAQQAQQAGLVSDVFPSDLTLEYALQLASKMARHSPLALQAAKQALRQSQEVALQ
                     AGLAQERQLFTLLAATEDRHEGISAFLQKRTPDFKGR"
     gene            24652..25440
                     /gene="paaG"
                     /locus_tag="ACHY1N_001945"
     CDS             24652..25440
                     /gene="paaG"
                     /locus_tag="ACHY1N_001945"
                     /EC_number="5.3.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
                     isomerase PaaG"
                     /protein_id="HFS4044266.1"
                     /translation="MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVER
                     DDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPV
                     ICAVNGVAAGAGATLALGCDIVIAARSAKFVMAFSKLGLVPDCGGTWLLPRVAGRARA
                     MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINS
                     AETNTLDTQLDLECDYQRLAGRSADYREGVSAFLAKRSPQFTGK"
     gene            25442..26869
                     /gene="paaH"
                     /locus_tag="ACHY1N_001946"
     CDS             25442..26869
                     /gene="paaH"
                     /locus_tag="ACHY1N_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008691 - 3-hydroxybutyryl-CoA
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase PaaH"
                     /protein_id="HFS4044267.1"
                     /translation="MMINVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRA
                     IDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKAL
                     FAQLAEVCPPQTLLTTNTSSISITAIAAEVKNPERVAGLHFFNPAPVMKLVEVVSGLA
                     TAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDA
                     ALRDGAGFPMGPLELTDLIGQDVNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGK
                     KSGLGVYDWRAEREAVVGLEAVSDSFSPMKVEKKSDGVTEIDDVLLIETQGETAQALA
                     IRLARPVVVVDKMAGKVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWR
                     TVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQH
                     HYGEERYRPCSLLRQRALLESGYES"
     gene            26859..27281
                     /gene="paaI"
                     /locus_tag="ACHY1N_001947"
     CDS             26859..27281
                     /gene="paaI"
                     /locus_tag="ACHY1N_001947"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyphenylacetyl-CoA thioesterase PaaI"
                     /protein_id="HFS4044268.1"
                     /translation="MSHKAWQNAHAMYENDACAKALGIDIISMDEGFAVVTMTVTAQM
                     LNGHQSCHGGQLFSLADTAFAYACNSQGLAAVASACTIDFLRPGFAGDTLTATAQVRH
                     QGKQTGVYDIEIVNQQQKTVALFRGKSHRIGGTITGEA"
     gene            27281..28486
                     /gene="paaJ"
                     /locus_tag="ACHY1N_001948"
                     /gene_synonym="paaE"
                     /gene_synonym="ydbW"
     CDS             27281..28486
                     /gene="paaJ"
                     /locus_tag="ACHY1N_001948"
                     /gene_synonym="paaE"
                     /gene_synonym="ydbW"
                     /EC_number="2.3.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase"
                     /protein_id="HFS4044269.1"
                     /translation="MREAFICDGIRTPIGRYGGALSGVRADDLAAIPLRELLVRNPRL
                     DAECIDDVILGCANQAGEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAAR
                     AIKAGDGDLLIAGGVESMSRAPFVMGKATSAFSRQAEMFDTTIGWRFVNPLMAQQFGT
                     DSMPETAENVAELLKISREDQDSFALRSQQRTAKAQSSGILAEEIVPVVLKNKKGVVT
                     EIQHDEHLRPETTLEQLRGLKAPFRANGVITAGNASGVNDGAAALIIASEQMAAAQGL
                     TPRARIVAMATAGVEPRLMGLGPVPATRRVLERAGLSIHDMDVIELNEAFAAQALGVL
                     RELGLPDDAPHVNPNGGAIALGHPLGMSGARLALAASHELHRRNGRYALCTMCIGVGQ
                     GIAMILERV"
     gene            28513..29826
                     /gene="paaK"
                     /locus_tag="ACHY1N_001949"
     CDS             28513..29826
                     /gene="paaK"
                     /locus_tag="ACHY1N_001949"
                     /EC_number="6.2.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase PaaK"
                     /protein_id="HFS4044270.1"
                     /translation="MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKF
                     DAAGVHPDDFRELSDLRKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKPTV
                     VGYTQNDIDNWANIVARSLRAAGGSPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
                     MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPW
                     TQAMRKEIERRLGITALDIYGLSEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPHDG
                     TPLADGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRRMDRISGRSDDMLII
                     RGVNVFPSQLEEEIVKFEHLSPHYQLEVNRRGHLDSLSVKVELKESSLTLTHEQRCQV
                     CHQLRHRIKSMVGISTDVMIVNCGSIPRSEGKACRVFDLRNIVGA"
     gene            29927..30877
                     /gene="paaX"
                     /locus_tag="ACHY1N_001950"
     CDS             29927..30877
                     /gene="paaX"
                     /locus_tag="ACHY1N_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation operon negative
                     regulatory protein PaaX"
                     /protein_id="HFS4044271.1"
                     /translation="MSKLDTFIQHAVNAVPVSGTSLISSLYGDSLSHRGGEIWLGSLA
                     ALLEGLGFGERFVRTALFRLNKEGWLDVSRIGRRSFYSLSDKGLRLTRRAESKIYRAE
                     QPAWDGKWLLLLSEGLDKATLADVKKQLIWQGFGALAPSLMASPSQKLADVQTLLHEA
                     GVADNVICFEAQIPLALSRAALRARVEECWHLTEQNAMYETFIQSFRPLVQLLKEAAD
                     ELTPERAFHIQLLLIHFYRRVVLKDPLLPEELLPAHWAGHTARQLCINIYQRVAPAAL
                     AFVSEKGETSVGELPSPGSLYFQRFGGLNIEQEALCQFIR"
     gene            30859..31449
                     /gene="paaY"
                     /locus_tag="ACHY1N_001951"
     CDS             30859..31449
                     /gene="paaY"
                     /locus_tag="ACHY1N_001951"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
                     /protein_id="HFS4044272.1"
                     /translation="MPIYQIDGLTPVVPEESFVHPTAVLIGDVILGKGVYVGPNASLR
                     GDFGRIVVKDGANIQDNCVMHGFPEQDTVVEEDGHMGHSAILHGCIIRRNALVGMNAV
                     VMDGAVIGENSIVGASAFVKAKAEMPANYLIVGSPAKLIRELSEQELAWKKQGTHEYQ
                     VLVTRCKQTLHQVEPLREVEPGRKRLVFDENLRPKQ"
     gene            31681..32541
                     /gene="pdxI"
                     /locus_tag="ACHY1N_001952"
     CDS             31681..32541
                     /gene="pdxI"
                     /locus_tag="ACHY1N_001952"
                     /EC_number="1.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 4-dehydrogenase"
                     /protein_id="HFS4044273.1"
                     /translation="MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLRE
                     ALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPA
                     ELQKAVHDNLRNLGLDVLDVVNLRIMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIG
                     LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALARDGIAYVPFFPLGGFTPL
                     QSSTLSDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEV
                     LSTLDGISRE"
     gene            32605..34911
                     /gene="ydbD"
                     /locus_tag="ACHY1N_001953"
     CDS             32605..34911
                     /gene="ydbD"
                     /locus_tag="ACHY1N_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing bactofilin"
                     /protein_id="HFS4044274.1"
                     /translation="MFKARICGWIGLLPLFMLSLPVQAELRCVANTVDIEPFFSAATA
                     EDKQQVEQAINSSVNLVPFGLSASDWKVHRGDLVVEGNIESNQKLIVLGNLTVKGNIS
                     TFSLSNPWVILGNVTATNIVTDSPLLITGSINASGLVFIDSYYDNPSSIKGSINARGI
                     FINDIIAPVVASSTNSEFMVRASDKNDTENVKKALMIINPDAYYWGLINDEDALKEIF
                     KRSNIRMAGNVCNQMKKEALFRPKPSPELVQELQMLDEGNVAAFEGRDIATFDLAIMR
                     TLPRLKGISANLRKQLINSNDEQTIESMARYMPDNEILELTDQQLGYQPVVLGLLDRE
                     PLSVEIMTRMSRLPDGVGPLNLALRENLPLDIVMTLAKRDWDMIIQELYKDAWLLPES
                     IIDGYIRSDDSSIRQVGAGGQLTYNQAMQLANDSSNNVVTSLAFKLAEMKHHGQLLRM
                     TPQESDKVAAYLYQKFENDDDLIRVLFLALPDNLQFNFVKRMEKKSPAYFCCRDMQVI
                     HSDAALQRLLTRFNDPEGWSNLAKNQYLSTSMKQKIWQRALSHRKNNPKADSAAYETS
                     ADMILSELISHGEVDDQMLLNATSLIRLEDWDFLESALVSWDNLPAVVLKELQQNTPR
                     NDIWAKFFLRQENSSRAQVDEALRVYYALDPDALAQLDVLAKQPDRIWWSTLAKSNLT
                     FFKFGALNNRHTPPAVLAAEIDPEWWIVAMNNPRFPVDVLKARLKRDPLLALELVNPE
                     LDLVRQLALNGKTRAIREQAMRKLDELY"
     gene            35082..35687
                     /gene="ynbA"
                     /locus_tag="ACHY1N_001954"
     CDS             35082..35687
                     /gene="ynbA"
                     /locus_tag="ACHY1N_001954"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFS4044275.1"
                     /translation="MTLYQIKPLFQSLLRPTMFWLYKHHVTANHITLAALALSLLTGL
                     LLMLVAQPILFMLLPIVLFIRMALNALDGMLARECNQQTRLGAILNETGDVISDIALY
                     LPFLFLPESNASLVILMLFCTILTEFCGLLAQTINGVRSYAGPFGKSDRALIFGLWGL
                     AVAIYPQWMQWNNLLWSIASILLLWTAINRCRSVLLMSAER"
     gene            35687..36583
                     /gene="ynbB"
                     /locus_tag="ACHY1N_001955"
     CDS             35687..36583
                     /gene="ynbB"
                     /locus_tag="ACHY1N_001955"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFS4044276.1"
                     /translation="MLEKSLATLFALLILATLINHFLVWRLPERKEDEVTLRIRTWWG
                     IVICFSLVISGPRWMTLTFFALISFLALKEYCTLISVHFPRWLYWVIPLNYLFIGFNC
                     FELYLLFIPLAGFLILATGQVFVGDPSGFLHTVSAIFWGWIMTVFALSHAAWLLMLPT
                     TNIQGGALLVLFLLALTESNDIAHYLWGKSCGRRKVVPKVSPGKTLEGLVGGVITTMI
                     ASLIIGPLLTPLNTLQALLAGLLIGISGFCGDVVMSAIKRDIGVKDSGKLLPGHGGLL
                     DRIDSLIFTAPVFFYFIRYSCY"
     gene            36599..38356
                     /gene="ynbC"
                     /locus_tag="ACHY1N_001956"
     CDS             36599..38356
                     /gene="ynbC"
                     /locus_tag="ACHY1N_001956"
                     /EC_number="2.1.1.-"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional alpha/beta hydrolase/class I
                     SAM-dependent methyltransferase"
                     /protein_id="HFS4044277.1"
                     /translation="MENSRIPGEHFFTTSDNTALFYRHWPALQPGAKKVIVLFHRGHE
                     HSGRLQHLVDELAMPDTAFYAWDARGHGKTSGPRGYSPSLARSVQDVDEFVRFAASDS
                     QVGLEEVVVIAQSVGAVLVATWVHDYAPAIRGLVLASPAFKVKLYVPLARPALALWHR
                     LRGLFFINSYVKGRYLTHDRQRVASFNNDPLITRAIAVNILLDLYKTSERIIRDAAAI
                     TLPTQLLISGDDYVVHRQPQIDFYQRLRSPLKELHLLPGFYHDTLGEENRAQAFEKMQ
                     SFISRLYANKSQKFDYQHEDRTGPSADRWRLLSGGPVPLSPVDLAYRFMRKAMKLFGA
                     HSAGLHLGMSTGFDSGSSLDYVYQNQPQGSNAFGRLIDKIYLNSVGWRGIRQRKTHLQ
                     ILIKQAVADLHAKGLAVRVVDIAAGHGRYVLDALANEPAVSDILLRDYSELNVAQGQA
                     MIAQRGMSGRVRFEQGDAFNPEELSALTPRPTLAIVSGLYELFPENEQVKNSLAGLAN
                     AIEPGGILIYTGQPWHPQLEMIAGVLTSHKDGKPWVMRVRSQGEMDSLVRDAGFDKCT
                     QRIDEWGIFTVSMAVRRDN"
     gene            38346..39662
                     /gene="ynbD"
                     /locus_tag="ACHY1N_001957"
     CDS             38346..39662
                     /gene="ynbD"
                     /locus_tag="ACHY1N_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310040.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2/dual specificity phosphatase
                     family protein"
                     /protein_id="HFS4044278.1"
                     /translation="MITERRNVLLQGAGWLLLLAPFFFFTYGSLNQFTAVQDLNSHDI
                     PSQVFGWETAIPFLPWTIVPYWSLDLLYGFSLFVCSTTFEQRRLVHRLILATVMACCG
                     FLLYPLKFSFIRPEVSGVTGWLFSQLELFDLPYNQSPSLHIILCWLLWRHFRQHLAER
                     WRKVCGGWFLLIAISTLTTWQHHFIDVITGLAVGMLIDWMVPVDRRWNYQKPDQRRIK
                     IALPYVVGAGSCIVLMELMMMIQLWWSVWLCWPVLSLLIIGRGYGGLGAITTGKDSQG
                     KLPPAVYWLTLPCRIGMWLSMRWFCRRLEPVSKMTAGVYLGAFPRHIPAQNAVLDVTF
                     EFPRGRATKDRLYFCVPMLDLVVPEEGELRQAVAMLETLREEQGSVLVHCALGLSRSA
                     LVVAAWLLCYGHCKTVDEAISYIRARRSHIVLKEDHKAMLKLWENR"
     gene            complement(39713..40318)
                     /gene="azoR"
                     /locus_tag="ACHY1N_001958"
     CDS             complement(39713..40318)
                     /gene="azoR"
                     /locus_tag="ACHY1N_001958"
                     /EC_number="1.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HFS4044279.1"
                     /translation="MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLA
                     ANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNIS
                     TQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTF
                     LGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVAA"
     gene            40519..44421
                     /gene="hrpA"
                     /locus_tag="ACHY1N_001959"
     CDS             40519..44421
                     /gene="hrpA"
                     /locus_tag="ACHY1N_001959"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HFS4044280.1"
                     /translation="MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQ
                     AIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRF
                     SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHI
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGR
                     IAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEF
                     YDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVTPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKIT
                     FRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTEEGFAALHEKVRAELN
                     DTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDEDVK
                     EIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG"
     gene            44693..45493
                     /gene="ydcF"
                     /locus_tag="ACHY1N_001960"
     CDS             44693..45493
                     /gene="ydcF"
                     /locus_tag="ACHY1N_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF218 domain-containing protein YdcF"
                     /protein_id="HFS4044281.1"
                     /translation="MNITPFPTLSPATIDAINVIGQWLAQDDFSGEVPYQADCVILAG
                     NAVMPTIDAACKIARDQQIPLLISGGIGHSTTFLYSAIAQHPHYNTIRTTGRAEATIL
                     ADIAHQFWHIPHEKIWIEDQSTNCGENARFSIALLKQAVERVHTAIVVQDPTMQRRTM
                     ATFRRMTGDNPDAPRWLSYPGFVPQLGNNADSVIFINQLQGLWPVERYLSLLTGELPR
                     LRDDSDGYGPRGRDFIVHVDFPAEVIHAWQTLKHDAVLIEAMESRSLR"
     gene            45690..47129
                     /gene="aldA"
                     /locus_tag="ACHY1N_001961"
     CDS             45690..47129
                     /gene="aldA"
                     /locus_tag="ACHY1N_001961"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HFS4044282.1"
                     /translation="MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAE
                     DARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQQLAE
                     VEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIA
                     RKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAG
                     NPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDS
                     RVINSGQVCNCAERVYVQKGIYDQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAAL
                     ERVEQKVARAVEEGARVALGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVV
                     AFDTLEEAISMANDSDYGLTSSIYTQNLNVAMKAIKGLKFGETYINRENFEAMQGFHA
                     GWRKSGIGGADGKHGLHEYLQTQVVYLQS"
     gene            complement(47171..48172)
                     /gene="gap"
                     /locus_tag="ACHY1N_001962"
     CDS             complement(47171..48172)
                     /gene="gap"
                     /locus_tag="ACHY1N_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFS4044283.1"
                     /translation="MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYL
                     LKHDSNYGPFPWSVDFTEDSLIVDGKSIAVYAEKEAKNIPWKAKGAEIIVECTGFYTS
                     AEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAK
                     ALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLV
                     IPELSGKLKGHAQRVPVKTGSVTELVSILGKKVTAEEVNNALKQATTNNESFGYTDEE
                     IVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL"
     gene            48361..48891
                     /gene="cybB"
                     /locus_tag="ACHY1N_001963"
     CDS             48361..48891
                     /gene="cybB"
                     /locus_tag="ACHY1N_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
                     /protein_id="HFS4044284.1"
                     /translation="MENKYSRLQISIHWLVFLLVIAAYCAMEFRGFFPRSDRPLINMV
                     HVSCGISILVLMVVRLLLRLKYPTPPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGL
                     VMMYNRGNPWFAFGLTMPYASEANFERVDSLKSWHETLANLGYFVIGLHAAAALAHHY
                     FWKDNTLLRMMPRKRS"
     gene            49136..49309
                     /locus_tag="ACHY1N_001964"
     CDS             49136..49309
                     /locus_tag="ACHY1N_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044285.1"
                     /translation="MKKLALILFMGTLVSFYADAGRKPCSGSKGGISHCTAGGKFVCN
                     DGSISASKKTCTN"
     gene            49335..49403
                     /gene="yncP"
                     /locus_tag="ACHY1N_001965"
     CDS             49335..49403
                     /gene="yncP"
                     /locus_tag="ACHY1N_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YncP"
                     /protein_id="HFS4044286.1"
                     /translation="MNLLVRCAGKIPALALTWTCRP"
     gene            complement(49381..49530)
                     /gene="hokB"
                     /locus_tag="ACHY1N_001966"
     CDS             complement(49381..49530)
                     /gene="hokB"
                     /locus_tag="ACHY1N_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokB"
                     /protein_id="HFS4044287.1"
                     /translation="MKHNPLVVCLLIICITILTFTLLTRQTLYELRFRDGDKEVAALM
                     ACTSR"
     gene            49929..51569
                     /gene="trg"
                     /locus_tag="ACHY1N_001967"
     CDS             49929..51569
                     /gene="trg"
                     /locus_tag="ACHY1N_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein Trg"
                     /protein_id="HFS4044288.1"
                     /translation="MNTTPSHRLGFLHHIRLVPLFACILGGILVLFALSSALAGYFLW
                     QADRDQRDVTAEIEIRTGLANSSDFLRSARINMIQAGAASRIAEMEAMKRNIAQAESE
                     IKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAIINHE
                     SEQIRPLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLIT
                     FMVLRRIVIRPLQHAAQRIEKIASGDLTMKDEPAGRNEIGRLNRHLQQMQHSLGMTVG
                     TVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAASMEQLTATVKQNADNAHHA
                     SKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAV
                     EAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTM
                     STIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNASLVEEASAAAVS
                     LEEQAARLTEAVDVFRLHKHSVSAEPRGAGEPVSFATV"
     gene            complement(51607..52530)
                     /gene="ydcI"
                     /locus_tag="ACHY1N_001968"
     CDS             complement(51607..52530)
                     /gene="ydcI"
                     /locus_tag="ACHY1N_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4044289.1"
                     /translation="MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSK
                     TLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVRVLDAINTAGQSLHRKEGLNNDV
                     VRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSD
                     PELMTGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDAL
                     VQSQGCKIPSGCIETLSASLSRQLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGA
                     GEPIGILTRVDATFSSGCQLMINAIRKSMPF"
     gene            52747..54090
                     /gene="ydcJ"
                     /locus_tag="ACHY1N_001969"
     CDS             52747..54090
                     /gene="ydcJ"
                     /locus_tag="ACHY1N_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4044290.1"
                     /translation="MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVL
                     ENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQA
                     GVPVHSTAFRPIDDASLARNPFRVFTSLLRLELIENEILRQKAAEILRQRDIFTPRCR
                     QLLEEYEQQGGFNETQAQEFVQEALETFRWHQSATVDEETYRALHNEHRLIADVVCFP
                     GCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLF
                     AGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFP
                     DSEFLMRQQGLAWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVAAQPITYEDFLPVS
                     AAGIFQSNLGNETQTRSHGNASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL"
     gene            54315..55970
                     /gene="opgD"
                     /locus_tag="ACHY1N_001970"
                     /gene_synonym="mdoD"
     CDS             54315..55970
                     /gene="opgD"
                     /locus_tag="ACHY1N_001970"
                     /gene_synonym="mdoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein OpgD"
                     /protein_id="HFS4044291.1"
                     /translation="MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQR
                     FDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLD
                     AQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFW
                     FDTVKPGATTFTVYALLDSASITGAYKFTIHCEKSQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNP
                     KGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVC
                     FWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEK
                     WARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSD
                     STDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS"
     gene            56110..56334
                     /gene="ydcH"
                     /locus_tag="ACHY1N_001971"
     CDS             56110..56334
                     /gene="ydcH"
                     /locus_tag="ACHY1N_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415943.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HFS4044292.1"
                     /translation="MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDGRGY
                     NAEVVRMKKQKLQLKDEMLKILQQESVKEV"
     gene            56397..56933
                     /gene="rimL"
                     /locus_tag="ACHY1N_001972"
     CDS             56397..56933
                     /gene="rimL"
                     /locus_tag="ACHY1N_001972"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HFS4044293.1"
                     /translation="MTETIKVSESLELHAVAESHVTPLYQLICKNKTWLQQSLNWPQF
                     VQSEEDTRKTVQGNVMLHQRGYAKMFMIFKEDELIGVISFNRIEPLNKTAEIGYWLDE
                     SHQGQGIISQALQALIHHYAQSGELRRFVIKCRVDNPQSNQVALRNGFILEGCLKQAE
                     FLNDAYDDVNLYARIIDS"
     gene            complement(56928..57908)
                     /gene="ydcK"
                     /locus_tag="ACHY1N_001973"
     CDS             complement(56928..57908)
                     /gene="ydcK"
                     /locus_tag="ACHY1N_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcK family protein"
                     /protein_id="HFS4044294.1"
                     /translation="MRKYRLSEEQRAFSYQEDGTKKNVLLRQIIAISDFNDVIAGTAG
                     GWIDRETVLAQEGNCWIYDQNAIAFGGTVISGNTRITGTSVLWGEVYATDNVWIDNSE
                     ISQGAYISDSVTIHDSLVYGQCRIFGHALIDQHSMIVAAQGLTPDHQLLLQIYDRARV
                     SASRIVHQAQIYGDAVVRYAFIEHRAEVFDFASVEGNEENNVWLCDCAKVYGHAQVKA
                     GIEEDAIPTIHYSSQVAEYAIVEGNCVLKHHVLIGGNAVVRGGPILLDEHVVIQGESR
                     ISGAVIIENHVELTDHAVVEAFDGDTVHVRGPKVINGEERITRTPLAGLL"
     gene            58032..59024
                     /gene="tehA"
                     /locus_tag="ACHY1N_001974"
     CDS             58032..59024
                     /gene="tehA"
                     /locus_tag="ACHY1N_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HFS4044295.1"
                     /translation="MQSDKVLNFPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGL
                     VILAMIIWGLLTSAFITRLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFR
                     PLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALG
                     YTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSV
                     NGGEGDTLAKMLFGYGLLQLLFMLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGS
                     GSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLVRTERAVLMKAEDKE"
     gene            59021..59614
                     /gene="tehB"
                     /locus_tag="ACHY1N_001975"
     CDS             59021..59614
                     /gene="tehB"
                     /locus_tag="ACHY1N_001975"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HFS4044296.1"
                     /translation="MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRN
                     SLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILST
                     VVLMFLEAKTIPGLIVNMQRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYY
                     EGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK"
     gene            59917..60585
                     /gene="ydcL"
                     /locus_tag="ACHY1N_001976"
     CDS             59917..60585
                     /gene="ydcL"
                     /locus_tag="ACHY1N_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HFS4044297.1"
                     /translation="MRTTSFAKVAALCGLLALSGCASKITQPDKYSGFLNNYSDLKET
                     TSATGKPVLRWVDPSFDQSKYDSIVWNPITYYPVPKPSTQVGQKVLDKILNYTNTEMK
                     EAIAQRKPLVTTAGPRSLIFRGAITGVDTSKEGLQFYEVVPVALVVAGTQMATGHRTM
                     DTRLYFEGELIDAATNKPVIKVVRQGEGKDLNNESTPMAFENIKQVIDDMATDATMFD
                     VNKK"
     gene            complement(60684..61046)
                     /gene="tnpA"
                     /locus_tag="ACHY1N_001977"
                     /pseudo
     CDS             complement(60684..61046)
                     /gene="tnpA"
                     /locus_tag="ACHY1N_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278583.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            61116..>61370
                     /locus_tag="ACHY1N_001978"
     CDS             61116..>61370
                     /locus_tag="ACHY1N_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415949.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4044298.1"
                     /translation="MKRLQAFKFQLRPGGQQEREMRRFAGACRFVFNRALALQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKG"
BASE COUNT        15278 a        14437 c        15998 g        15657 t
ORIGIN      
        1 tgtttattta gacctgattc taatcacttt tcttgcccgg agtcattttt gacatgcccg
       61 ataacgctgg acacacctga gactggggtg ttcatgagaa actcacgagg tgctgagata
      121 tgctctctat atgataagga cgcgttagtg caacttgttg aaactggtgg agctcatcct
      181 ctgagtcgag aacctataac agaatcaatg attatgagaa aagatgaatg tcactttgat
      241 acaaaaagag aagctttttg ttgtaagtga taattaatga tataaatgta gttttatgta
      301 cttttatttt ttactaaagc aaaattaagt tattaaaatg gagggagagg aatgcctgta
      361 gatttaacgc cttatatttt acctggggtt agttttttgt ctgacattcc tcaagaaacc
      421 ttgtctgaga tacgtaatca gactattcgt ggagaagctc aaataagact gggtgagttg
      481 atggtgtcaa tacgacctat gcaggtaaat ggatatttta tgggaagtct taaccaggat
      541 ggtttatcga atgataatat ccagattggc cttcaatata tagaacatat tgaacgtaca
      601 cttaatcatg gtagtttgac aagccgtgaa gttacagtac tgcgtgaaat tgagatgctc
      661 gaaaatatgg atttgctttc taactaccag ttagaggagt tgttagataa aattgaagta
      721 tgtgcattta atgtggagca tgcacaattg caagtgccag agagcttacg aacatgccct
      781 gttacattat gtgaaccaga agatggggta tttatgagga attcaatgaa ttcaaatgtt
      841 tgtatgttgt atgataaaat ggcattaata catcttgtta aaacaagggc ggctcatcct
      901 ttgagcaggg aatcaatcgc agtttcaatg attgtaggaa gagataattg tgcttttgac
      961 cctgacagag gtaacttcgt tttaaaaaat taaggtagca atggcgggtt aacttttcgt
     1021 aaaatgaaat taattctcgg tacggcatgt aaaacgcggc acctcgtatg caagaacgtg
     1081 ccgcggttgg ctggtaagct tttcgatagt gcgagtatct aatgatttcc agccggaact
     1141 gattctattg gaaagaaatc atgggcgcca gattgattag ttatagattt ttactgtggc
     1201 aaaaatggga caaaaggccg caaaaggggc aaaaatgggg caaaaaaagt gtagattatt
     1261 gtgctttatt gtagttgtta atcctgccta acatattgaa aaacataaaa gttattgttc
     1321 gtcagatagt tgcggttttt actctgactt gttcaggttg tattgttctt tcttactaat
     1381 ttcttgattt tgcgacattt aaaagcgact caattcgtta tatggcatca gaagagtatg
     1441 cgtcatgccg gaatgcccag cataagaaat ctgatataaa aacagtggcg tgtatggtac
     1501 ggattagagg ggaaaatgtc agcacatttg cgaaatgaat caaaaagccc gcagcaatgt
     1561 gcgggcgtta gtgtcagcgc acaaccagca cggagcactc tgcgtgacgc actacagctg
     1621 cggcgttgga accgagcaga taagtggtga tatccggtcg atgggaagca atgatgatca
     1681 tatgagcggg gatcttcttc gccatttcca gaatgcggtc tttgggcgag ccttcctcaa
     1741 catggacatg cactctgtcg gttggcagtt taaatttttt aatgatctct tccagttgcg
     1801 atttggcttc cgctttcagg tcatccattg ccggtaattc tgcggaatac gctaaaccca
     1861 gagaggcata gtagggcagt gaaggtatta ccgtcaggaa atgaacctct gcatcatcaa
     1921 tctttgcctc tgcctcaacg tggctaatca cgcgttgagt taattctgaa tcggaaatat
     1981 cgatagggac aagaatcgtt ctgttcataa aacctcctgt tttagtatcc gcataaagtg
     2041 taacgccaga tgacactttt tgtgtaatga cggagttcac atttttaatt tagatcaaag
     2101 gaggaagaat aagcagaaaa agcccgccat aacagcgggc aggaggattt agaactgata
     2161 aaccagacct aaagcgacaa tatcatcggt agagatgcca ttggcagcgt agaaactgtc
     2221 atcttcatcc aacaggttga ttttatagtc aacataagtg gacatgtttt tattgaaata
     2281 gtaagtcgcg ccaacatcgg cgtatttaac cagatcttta tcatcaacac ctgccgggtt
     2341 gtctgcacca ccggcagcgt gcaggtcacg gcctttagac atcaggaaag agactgccgg
     2401 acgcagacca aaatcaaact ggtactgtgc agtgacttca aagttctggg ttttgtttgc
     2461 aacagcataa tcgctgtcgc caaacggggt catattacgc gtttctgaat acatggttgc
     2521 caggtaaata ttgttagcat cgtattttag cccagcagtc cacgcgtctg ctttatcacc
     2581 acccgccgca gtatggttaa cctgatcatt ggtgcggtca gaagaggtgt atgccgcacc
     2641 agcgctaaag cccatgccta aatcatatgt tgtggaaaga ccccagccgt caccgttttc
     2701 atggcgaaca tcacgtccgt tgttggtgcc ttcctgacca ttactggcac cttcgttgtt
     2761 accttgatac tgcaccgcga agttcagacc atttaccaga ccgaagaaat cagtattacg
     2821 ataagtcgcg acgccattgg ctcgaccagt cataaagttg tctgcattgg tataagagtc
     2881 accgccaaat tcaggcagca tatcggtcca gccttcgatg tcgtacatta cgccataatt
     2941 acgtccgtaa tcgaaagaac cgtaatctgc aaatttcagc ccggcaaatg ccagacgggt
     3001 ccatgactgg ttttttgaag attcagtgtt gtttgcctga atattgtatt cccattgacc
     3061 gtagccagtg agttgatcgt taatttgggt ttcgccttta aaacccagac gcgcatagct
     3121 ctggtcgcca tctttcgccg aattatcaga aaaataatgc aggccatcaa ctttgccata
     3181 cagatctaat ttgttgccgt ctttattata aacttcggct gcatgtgcag cacctgcggc
     3241 gagcagggca ggaattaaaa gtgccagtac tttgcttttc attgaataaa tcctttagtt
     3301 attttatttg ccttttatcc ccatttcggg gagtgaaaac atcctaaagg agaagttcag
     3361 ttagccgata aatatcattt gttacgcctt aagtaaaacc ttaatcaaat aattcctctg
     3421 aaatgataat aagtctggtg aatgtatcga agataataca tacaaaataa aaattatact
     3481 tttaattttc tatacgttat tctgcgcggg ttatatgcct ttattgtcac agattttatt
     3541 ttctgttggg ccattgcatt gccactgatt ttccaacata taaaaagaca agcccgaaca
     3601 gtcgtccggg ctttttttta gaattggata atccttatcc agagcattta atcggtgttg
     3661 cttttttccg cttttccggc catttgtgcc aggaagtcat agcgtttttg caaatcagct
     3721 gcagcatctt tccataactg ttctgccact tctggctgct gcgaattcag ccgacggaaa
     3781 cgttgctcgt gaagtaacgt ttcttccagt gctactgacg gcgggcgtga atccagcgcc
     3841 agcggcagtt tgccttcatc ggcacgacgc ggatcgaagc gatatagcgg ccagaagccg
     3901 gtagctgtga gttggcgcat ctggtcgtgg ctgagtgcca gatcgtaacc atgctcttca
     3961 catgggctat aagcgatgat cagcgatggc cccggatacg cttccgcttc ctgaatcgct
     4021 ttcaccgtct ggttgagctg cgcgccgaga gaaatctgcg ccacataaac atgaccgtac
     4081 atcatcatac tgacgccaag atctttacgc gctttacgtt tgccgtgctc gccaaattta
     4141 gttactgcac ccagcggtgt cgctttcgac gcctgaccac cggtgttgga atagcattgc
     4201 gtatccagca ccagaatgtt gacgttttcc gtcaaactca atacatgatc cagaccgcca
     4261 aagccgatat cgtaagccca gccatcacca ccaatcagcc agattgattt ttccaccagt
     4321 gcatctgcat cacgtagcag ttcatgtgct tcggcaacat cgttgagttg ctggcgtaaa
     4381 gctgcgacct gttctcgacg aacctctggc gtagcgtctg atttcaacgc cgtcagtaat
     4441 tccgccggga ttttatcggc aaattgatcc agcagacgca gcacgcggac acggtgttga
     4501 tcgaccgtca ggcggaaacc aaggccaaat tcggcattat cttcaaatag agagttcgcc
     4561 catgccggcc cacgaccgtt ggcatcggtg gtatacggtg tagagggcag gttaccgcca
     4621 taaattgaag aacagccggt ggcgttagcg atcaacatcc ggtcgccata gagctgagtc
     4681 agtaatttaa tatacggcgt ctcgccacaa ccggagcaag cacctgaata ttcaaacagc
     4741 ggtgtaatca gctgcgatgt acgaatatca atacgttcca gtttgctacg gtcgatttct
     4801 ggcaggttga ggaagaaatc gtaattgatt ttctcttctt cgacatgttc caggcgcgac
     4861 atcatattga tggctttaat ctctggattc tgacggtctt tcgccgggca aacttcgacg
     4921 cacaggttac aaccggtgca atcttccggt gccacctgca agacatattt ctgcccgcgc
     4981 atatcacgcg atttcacatc cagcgaatgc aggctggcag gggcgttttc catcgcttca
     5041 ggcggcacca cttttgcgcg aatagctgag tgtgggcaag cggcaacgca gtggttacat
     5101 tgggtacaga gttcctcttt ccagatgggg atctcttcgg cgatattgcg tttttcccag
     5161 cgagtggtgc ccatcggcca ggtgccgtct ggcggcagcg ccgaaacggg gagggcatca
     5221 ccaagccctg cgagcatcgc tgcggttacg gttttcacga aatcaggggc ggcatcggaa
     5281 accactggcg gtcgattggc gctgtgcgga tttaccggtt gcaacggaac ttcttctacg
     5341 gattcacgcg ccagcgccag agcctgccag ttgcgttcca ccagatcctg gcctttgcta
     5401 ctgtaacttt tggcaatcgc accctgcaat tctgcgaggg cgctatcgcc aggcagaatt
     5461 tgcgtcagat ggaaaaaagc catctgcatg acggtattaa tacgggccgc caggccacat
     5521 tcgcgggcga ttttcgccgc gttaatcaca tagaagcgcg cttttttctg atttagcacg
     5581 gcctgaactt cctgcggcaa gcgcgaccac acttcatctg cgctgtacgg cgtgttgagc
     5641 aggaaaatgc cgccaggttt taaacgctca gccatctgat atttatcgat aaactgcaac
     5701 tggtggcagc caacaaaatc agcctgggaa atgagataag cggaacgaat cggctgttcg
     5761 ctcacgcgaa ggtgagaaac cgtcaggccg cccgcctttt tggagtcgta aacaaaatag
     5821 ccctgtgcgt accacggcgt ggaattaccg ataatcttga tattgttttt ggtcgcggaa
     5881 acgctgccat cactaccaag gccataaaac aaggcttcca gtttcgccga gtttggcagg
     5941 gtgttttccg gcaacggcag tgacagattg gtcacatcat cgtaaatacc aaccgtaaag
     6001 cgcgctttcg gtttagccgc gttgagctcg gcaaataccg ccagtacaca gtccgggcca
     6061 aattctttgg atgaaagacc atagcgccca ccaatgacac ggggcagagt ttcgcgctcg
     6121 ccattattaa aggcttctgc cagtgcggtc attacatcca gatagagcgg ttctgcctgg
     6181 gcaccgggtt ctttggttct gtccagtacc gccacgctgc gtacggatcc cggcagagct
     6241 tgcagcaagt gtttggcgga gaagggacgg tacaggcgaa ctttcagcac gccaactttt
     6301 tcgccacggg ttagcaattc atcaaccact tcttcacagg tgccaatggc agagcccatc
     6361 aggataatca cccgttccgc ttgcggatgc ccgtaatatt caaacggctg atactgacga
     6421 cctgtcgcgg cagagaaatc attcatcgcc tgttcaacat ggtcatagac cgcgtcgtac
     6481 catgggttgg tggcttcgcg agactggaaa taagtgtcag gattggcgga cgtaccgcgg
     6541 atcaccggat gttccgggtt gagcgcccgg gcgcgatgag catcaatttc ggcctgcggc
     6601 atgagatcaa gaatagtgtc atcggccagc gggacaattt tattgatttc gtgggacgtg
     6661 cggaaaccat caaagaaatg aataaatggc acgcggctct tcagcgttgc gatgtgcgaa
     6721 atgagagcaa aatcttgcgc ttcctggacg ttagccgcac acaacatcgc gcaacccgtc
     6781 tggcgcaccg ccatgacgtc ggaatgatcg ccaaaaatag agagtgcatg tgtggcaacg
     6841 gtacgtgccg ctacatgcag gacaaacggt gtgagttcgc ctgccagttt gtacagcgtc
     6901 gggatcatca gcagcaaacc ctgcgatgac gtaaacgatg ttgaaagggc acccgtctgc
     6961 aaagcgccat gcacggtagc gatagcaccc gcttccgact gcatttcaac cacgcgtggt
     7021 gtgtctcccc aaacgttctt caagccgttt ccggcccagg catcagcctg ttctgccatc
     7081 gtggaactgg gggtaatagg gtagatggcg ataacttcac tggtgcgaaa cgccaccgaa
     7141 gcaaccgcgc cattaccgtc aatagtaatc atatgacacc cttacattgc gcaaatgagg
     7201 ggcgcacgaa attgctgcgc gcccagtagt aatccttcaa ttttagcaaa tggctttctt
     7261 ctgcattttc gcttttgtgt cccccacatc agcgtaatga atgttttgat caaacagagg
     7321 gcaaaaaaat agccataaaa aagtaaaaat gcggggcaac gcgcaggaca gctctcgacg
     7381 ccgccctctg tgctgcctat tatttatggc ggtgtcgttt ggcttgaaga tcagaggaag
     7441 aagagatgcg agcagcgttt tgggtagggt gtgccgcttt attgttgtcg gcgtgtagta
     7501 gtgaacctgt tcagcaggcg actgcggcgc acgtagcgcc aggtttaaaa gcgtcgatgt
     7561 ccagtagtgg agaagcaaat tgtgcaatga tcggcggttc gctttctgtt gcccgtcaac
     7621 tggatggtac ggcgattggg atgtgtgcat tacccaacgg caaacgctgt agcgaacagt
     7681 cacttgccgc cgggagctgt ggcagctatt aattcattaa atccgccagc ttataagtta
     7741 atgtctgttt cgcggtcgcc agcgttaact ggttcgcggt cagatccact tgtgcacctt
     7801 ctttcagcat ttcgctaatg gtgttatcga gttcattaag ctgcgggtta gcgcacatca
     7861 tacgggtcat tgccagccct ttggctgtca gttcaccatt agacagtttg ccttcaccgc
     7921 taaagcggtt acacatgctg ccggaaatca tcattttttc accaaagctg atttctggcg
     7981 gatttttatc gctggtcacg ggcttaccgt ttacgctttc cagcacaaag cgatgatgct
     8041 gtagctgttc tggcgtaaca gcaattttgt cattacttac acatcccgcc atcagcaggc
     8101 ttagcgcaac aaacgcggct actttcttca ttgtggttct caattacagt ttctgactca
     8161 ggactatttt aagaatagag aatgaaaggt cattggggat tatctgaatc agctcccctg
     8221 gattgcaggg gagcggcaag attaaaccag ttcgttcggg caggtttcac ctttttccag
     8281 attgcttaag ttttgcagcg tagtctgaga aatactggtc agagcttctg ctgtcaggaa
     8341 tgcctggtgc ccggtaaaca gcacgttgtg gcaggcagac aggcgacgga atacgtcatc
     8401 ctggatcacg tcgttggatt tatcttcaaa gaacagatcg cgttcgttct catacacgtc
     8461 catacccaac gaaccaattt tctgattttt cagcgcttca attgctgcct gagaatcaat
     8521 caatgcaccg cgactggtat tgacgatcat cacgccattt ttcatctgat cgaaggcggc
     8581 ttcgttcaac agatggtagt tttccggtgt cagcgggcag tgcagagaga taacgtctga
     8641 ttcagagaac agggttggca gatcgacata ctccacaccg agttccagcg ccgctgcact
     8701 tggatacgga tcgaacgcca gcagacgcat accaaaacct ttcagaatgc gcagcatcgc
     8761 cacaccgatt ttaccggtac cgataacgcc tgccgttttg ccatacatag taaagccggt
     8821 cagaccttcc agagagaagt tagcgtcacg ggtacgctga tacgcgcggt gaatacggcg
     8881 gttcagcgtc atcatcatac cgatggcgtg ttcagcaacg gcctctggat cataggctgg
     8941 aacacggact actttcagcc ccagttcttt tgccgcgtca aggtcgacgt tattgaaacc
     9001 ggcacagcgc agggcgatat atttaacgcc gtgctttttc agctcttcca gcaccgggcg
     9061 gctgccgtca tcgtttacga aaatacatac cgcttcgcag ccattggcag ttttagcggt
     9121 tttttccgtc agcagaaagt caaaaaattc cagctcaaag ccaaaggact cgttcacctg
     9181 ttgcaggtac ttcttgtcgt actgttttgt gctataaacg gcgagtttca taagactttc
     9241 tccagtgatg ttgaatcaca tttaagctac taaaaatatt ttacaaaatt tcaaatttaa
     9301 ttgaaagcta tggcgatatt gaaaaattca tcaacaacta tgcttagtgt aggcgcaacc
     9361 ttcaactgaa cggttaaaca tgccacaata cccgtattga atgcttaatt tttcgctaaa
     9421 tcaggatatt aactacccat gctgggtaaa tataaagccg ttctcgcgct gttattactg
     9481 attattcttg tgccgttgac gctgttgatg acgctcgggc tgtgggttcc cacgctggcg
     9541 ggcatctggc taccgctcgg gacacgtatt gcattagatg aaagcccacg cattacgcgt
     9601 aaaggtttaa tcattcccga tctccgttat ctggtgggag attgtcagct tgcgcatatc
     9661 accaacgcca gcctttcaca tcccagccgc tggttattga acgtcggcac ggtagaactt
     9721 gattctgctt gtctggcgaa attgccgcag acggagcaat cgccagctgc tccaaaaacc
     9781 ctcgcgcagt ggcagtccat gctgcctaac acctggatca atatcgataa actgattttt
     9841 tctccctggc aggaatggca gggaaaactc tctctcgcat taacctctga tatccagcaa
     9901 ctgcgttatc agggcgaaaa agttaaattt caaggccagc tgaaagggca acaacttaca
     9961 gtcagcgaat tggatgtcgt cgcgtttgaa aatcagccgc cggttaaact ggtgggggaa
    10021 tttactatgc cgctcgtgcc ggatggactt cctgtaagtg ggcatgctac tgcgacgtta
    10081 aacttgccgc aggaaccgtc actggtggat gcagagctgg actggcagga aaatagcggg
    10141 caattgattg tgctggcacg ggataacggc gatccgttgc tcgatttgcc gtggcaaatt
    10201 actcgtcaac aattgaccgt aagcgatggt cgctggagtt ggccgtatgc aggttttcct
    10261 ttgagtggcc gactgggtgt caaagtcgac aactggcagg cagggcttga gaacgctctg
    10321 atcagcggac gactgagtgt gctgacccag gggcaagcgg gtaaaggcaa cgcggtgcta
    10381 aattttggcc caggaaaatt aagcatggat aacagtcagc tgcctctgca gctgaccggt
    10441 gaagcgaaac aggcggacct cattttatat gcccgtttac ctgcgcagct aagtggaagt
    10501 ctgtctgacc caacgctgac ctttgagcca ggcgcgttac ttcgttcaaa gggaagagtc
    10561 atcgattcgc tggacatcga tgaaatccgc tggcctttag cgggtgtaaa agtcacccaa
    10621 cgtggtgttg acggacgttt gcaggccatt ttgcaggcgc atgaaaatga actgggcgat
    10681 ttcgtgctgc atatggatgg gctggcgaat gattttctcc ctgacgcggg ccgctggcag
    10741 tggcgctact ggggaaaagg cagttttaca ccgatgaatg ccacctggga tgtcgcagga
    10801 aaaggtgaat ggcatgacag cacgattacg ctgaccgacc tctccaccgg tttcgaccag
    10861 ttacaatacg gtacgatgac ggtagaaaag ccgcgattaa ttctcgacaa gcccgtcgtc
    10921 tgggtacgtg acgcacagca tccctccttc agcggcgcgc tgtcactgga cgccgggcaa
    10981 acgctgttca ctggcggcag tgtgttaccg ccatcaacct taaaatttag cgtcgatggg
    11041 cgcgatccga cgtatttcct ctttaaaggc gatttacatg ctggtgagat tggcccggtt
    11101 cgggtaaatg gtcgctggga cggtattcgt ctgcgcggta acgcctggtg gccaaaacaa
    11161 tcactgactg tattccagcc gctggtgcca cccgactgga agatgaactt acgcgatggt
    11221 gaactgtatg ctcaggttgc attttctgct gcgccggaac aaggattccg cgcgggaggg
    11281 cacggcgtgt tgaaaggcgg tagtgcctgg atgccagata atcaggttaa cggtgtcgat
    11341 tttgtcctgc ctttccgttt tgccgatgga gcctggcatc tggggactcg cggccccgtt
    11401 acgttgcgaa ttgccgaagt gattaatctg gtgacagcga aaaatattac ggctgatttg
    11461 caagggcgtt atccgtggac tgaagaagaa cccttgctgt tgactgatgt tagcgtcgat
    11521 gtgttaggcg gtaacgtact gatgaaacaa ttacgtatgc cgcaacatga cccggcgctg
    11581 ttgcggctga ataatctctc atccagcgaa ctggttagcg ccgtcaatcc gaaacaattc
    11641 gccatgtccg gggcatttag tggtgcattg ccattatggc taaacaacga aaaatggata
    11701 gtgaaagatg gttggctggc aaatagcggg ccaatgacct tgcggctgga taaagacacc
    11761 gcagatgcgg tggtgaaaga caatatgact gcgggttcag caattaactg gttgcgctat
    11821 atggaaatta gccggtcatc gacaaaaatt aacttagata atctcggttt attaaccatg
    11881 caggccaaca ttacaggtac cagtcgcgtt gatggtaaaa gcggtacggt aaaccttaat
    11941 taccatcatg aagagaatat ttttacgctg tggcgcagtt tacgctttgg cgataatctc
    12001 caggcatggt tggagcagaa cgcacgtctg ccgggaaatg actgtccgca aggaaaagag
    12061 tgtgaggaaa aacaatgaaa attttactgg ctgcgttgac gtcatctttt atgctggttg
    12121 gctgtacgcc tcgcattgaa gtcgctgcac ctaaggaacc gatcactatc aatatgaacg
    12181 ttaaaattga gcatgagatc atcatcaagg cagacaaaga tgtcgaagag ctgcttgaaa
    12241 ctcgtagcga tcttttctga ggcgatgatg aagaaaacat tacttctttg tgcgtttctt
    12301 gttgggctgg taagcagcaa tataatggca ttgactctgg atgaagccag aactcagggg
    12361 cgggtaggtg aaacatttta tggttatctg gttgcgctga aaacggatgc tgaaacagag
    12421 aaattagtaa ccgacattaa tgccgaacgt aaagcgagtt accaacaact ggcaaagcaa
    12481 aataatgtgt cggtagatga tatcgcgaaa ctcgccgggc aaaagctcgt agctcgggcc
    12541 aaaccggggg aatatgtaca agggataaac ggtaaatggg tgcgaaaatt ttaatagcaa
    12601 aaccgcaata tcgggataat gctacaggag aaagcgattg atctattttc ctgaaacaag
    12661 gtgaatatta aaaaactcct gttaaattgc cttttgccct gaaaaatgca tagtcaaata
    12721 tctgttttaa ctaattggcg ttgcagtaca tgcaacgcga attagttagc ggaatttacg
    12781 ccgatactcg cctggcgtca tcccaaagcg ttgcttaaat actgttgaaa aatgactctg
    12841 gtcggaaaat ccccaatgaa aaccaatgcc tgccagtttt tcatcatctg cggcatggcg
    12901 aatcgcatca gcacaaaaat cgagacgacg gttacgaata tattgcgcga ccaccaaacc
    12961 tttatcggca aacattcggt acaaactacg tactgacata cctgtctctc cggctatcca
    13021 ctccgggcgt aatatctctt cgcgaatatt atcgtctatc agcgtaacca ctttttgaaa
    13081 ctgacgttca cggcgaggtt gaacagattc ccgctgatga agtaccgggc gcagcagaca
    13141 caccatcgcc tgtagcgcag cttcactttc tgtttcagaa agtgccgggt tattcatgct
    13201 ctcctgtaac aggcgatgac tgagttgcac catgggtaag tcagcgtcca gtctttctgc
    13261 gcagacaggt ttttgatggg gaaaatattg ttccagcaga gtgcgtggta aaagtaatga
    13321 aatctgttta gaagactcct gccagtaaag cgaacagggg cgtgaggcat cgagtaacgt
    13381 aatatcgcca gcgccaatct gcacctgacg ctcatcctgc tccattattg cctgaccact
    13441 aagttgaaaa acggtgtaaa accaggcatc gtcgctgcct tttacctcct gccaggtgcg
    13501 gtataaattc actccgttgg ttgtcacggt gctcagcttt agtcctttgg caaaatgcgt
    13561 ttccagtaca cccgtgtaac gctcagtcag caggcgtccg gtaaaatttc cgcatacctg
    13621 attgatttgg gaaagccatt gctgaaactc attatccact gcggggttca tggcacgttt
    13681 tcgctctgtg aaatgtattt ttattgttgc atttgtgttg caataaacga agctaatgag
    13741 cctgactata ggaaataagt cttgtcaggc atagagacat aagcggttat tgtcacgatt
    13801 tgcggagctt gtcacagctg acaaagcgaa tgtcacagcg aaaaaagtga cttttcttgt
    13861 cgctgcgtac actgaaatca cactgggtaa ataataagga aaagtgatga cagagccgca
    13921 tgtagcagta ttaagccagg tccaacagtt tctcgatcgt caacacggtc tttatattga
    13981 tggtcgtcca ggccccgcac aaagtgaaaa acgattggcg atctttgatc cggccaccgg
    14041 gcaagaaatt gcgtctactg ctgatgccaa cgaagcggat gtagataacg cagtcatgtc
    14101 tgcctggcgg gcctttgtct cgcgtcgctg ggccgggcga ttacccgcag agcgtgaacg
    14161 tattctgcta cgttttgccg atctggtgga acagcacagt gaggagctgg cgcaactgga
    14221 aaccctggag caaggcaagt caattgccat ttcccgtgct tttgaagtgg gctgtacgct
    14281 gaactggatg cgttataccg ccgggttaac gaccaaaatc gcgggtaaaa cgctggactt
    14341 gtcgattccc ttaccccagg gggcgcgtta tcaggcctgg acgcgtaaag agccggttgg
    14401 cgtagtggcg ggaattgtgc catggaactt tccgttgatg attggtatgt ggaaggtgat
    14461 gccagcactg gcagcaggct gttcaatcgt gattaagcct tcggaaacca cgccactgac
    14521 gatgttgcgc gtggcggaac tggccagcga ggctggtatc cctgatggcg tttttaatgt
    14581 ggtcaccggg tcaggtgctg tatgcggcgc ggccctgacg tcacatcctc atgttgcgaa
    14641 aatcagtttt accggttcaa ccgcgacggg aaaaggtatt gccagaactg ctgctgatca
    14701 cttaacgcgt gtaacgctgg aactgggcgg taaaaacccg gcaattgtat taaaagatgc
    14761 tgatccgcaa tgggttattg aaggcttgat gaccggaagc ttcctgaatc aagggcaagt
    14821 atgcgccgcc agttcgcgaa tttatattga agcgccgttg tttgacacgc tggttagtgg
    14881 atttgagcag gcggtaaaat cgttgcaagt gggaccgggg atgtcacctg ttgcacagat
    14941 taaccctttg gtttctcgtg cgcactgcga caaagtgtgt tcattcctcg acgatgcgca
    15001 ggcacagcaa gcagagctga ttcgcgggtc gaatggacca gccggagagg ggtattatgt
    15061 tgcgccaacg ctggtggtaa atcccgatgc taaattgcgc ttaactcgtg aagaggtgtt
    15121 tggtccggtg gtaaacctgg tgcgagtagc ggatggagaa gaggcgttac aactggcaaa
    15181 cgacacggaa tatggcttaa ctgccagtgt ctggacgcaa aatctctccc aggctctgga
    15241 atatagcgat cgcttacagg cagggacggt gtgggtaaac agccatacct taattgacgc
    15301 taacttaccg tttggtggga tgaagcagtc aggaacgggc cgtgattttg gccccgactg
    15361 gctggacggt tggtgtgaaa ctaagtcggt gtgtgtacgg tattaatctg gttcgctcat
    15421 aagtaaaaaa cggcacctgg tgccgttttt ttgtctgaaa caatcactta tctttcttca
    15481 gcgcccctag cgttggcgtt tcgtcaaaga agttccatgg tttaagcaga gtatgtaccc
    15541 attcggtcgg cataatcggc cactcttcgg cgcgggccac atgtgtggtg ccggtggtca
    15601 tccagacaac ggcgtcggtg ttgtccagcg actcgttatc tttactgtat tgtccaagac
    15661 cggtgtcatg agtagaacgg ttcggatatt tgccttccgg gaaacgctcg ccaggatgat
    15721 aacgcgttac ccaaagctgc ttgtccataa agcttaaacg atgatagatc cactcgtccg
    15781 gcgcgaactg ggcacctttt gctaccgggt gagtaccacc tgcataagga ataatttgat
    15841 aggaaactgg attgcccatg cggttctctt tgttcgggtt actcaacaga cgaatcgtgc
    15901 ccggatcaaa cttctgcgcg gcatcctgtt cattgccgat gttgtactga ttaacttgca
    15961 tggtactggt gcgtgggcca ccggcagtat tcggttttac cactgggtcc atcgccacca
    16021 ggctgttatt ctcgccatct acatccagat cgaggcggaa attataaata tgttggtgtg
    16081 tagtacccac gatattgtga tcgataagcg tgccgtagcg cgtgtcatct ttcgccgtct
    16141 catcgtgcat ggttttcgct ttaacacctt tcaccgcttc gatgcccgta gcaccggcat
    16201 caatgccaat agtgccgttt tcatggaaga tccagtcaaa aatgtagtca tagttaccca
    16261 ctgtactgat ccagcgcacc actaactccc ggcgttcggt actgacgttg ggctggccca
    16321 tttcctgatg cttatactcc ggcccggcat aacgttcaaa taccgcgata gcgcgaggga
    16381 tctccatcgg cacgccagtg tagtcggcga tggtttcatt aaggagcact gcgttagacg
    16441 gggcatcttt accacgagca attggtgagg ttagcgtgcc cataccgtag tcaccagagt
    16501 ccagatacgc tttaaagtac cagccaatat caggatcacc gtaaggcaca atcatgccgc
    16561 cgagagaacc ttcgtacatg actttgcgtt tggtgccatt gtcgttataa gtcacggtgg
    16621 agatcatcgg cccgacgcga gagttcatgc tgaggtgaaa atcccagttc cgccagtgaa
    16681 tcatatcgcc agtaatggtg taatttttac cttcaggctc aatgatttgc ataggcttaa
    16741 ctgccggagc aacgcggtca cggctatcaa atgggcgtgc ggtcattggc accggaacta
    16801 ccggaccttc ttcaatctta acgatttttt tctgttctaa atcaacgacc gccaccaggt
    16861 tttcgatggg atgtgcccag tagttgccat caccgacatc aagatagctg atgactttga
    16921 gcaaccgggc atcttgtttc aggccatctt taccatcgaa ataacctacg gtcagcggcg
    16981 tggtaatcac ttttttcgca tcagtaatac cgcgtttctt cacggcagcg gcaaattctt
    17041 cactgttgtt aataatgttc tgcacactgg cgaaatcatc cagcaacacc ataccgtggg
    17101 cgtctttagt gggttgccag gagagcagtt tgttgttttg cagatccacc accgcttcga
    17161 tgatatgttt gccgtcgagc ataatgacgt cggctttgcg cggctggtca accggtttgt
    17221 tttccagcgc aaacgcccag acagcttctt tatctggcgg tagcagggag atctcagtaa
    17281 aacgggtatt gggtttgaag tccgcggaag ctttaacaat ttcaacggcc tgtttaattt
    17341 cgtccgcagt tagcgcatta agtgggtgag ggcgcttttc tacctgaaag gtttgatcca
    17401 gcccggactg gaaaacatcg ttaataaagg tgtcagaaac ccaggcttta ttgtctttca
    17461 tcactaccgg tacttgcagt gccagaggct gaccattaac aattgctgtt tgcgcaccag
    17521 gcttcacttt cacgtacgcg ccatctttaa tcagggtaaa gagctgggcg tagtcgtccc
    17581 actgcacatc ggcaccaaat tctttaagcg ttttatccat tggcaccata tgcgcttcac
    17641 caccgtgggc aaataccggc gcttgccagg cgaaacttaa ggcgactgcc aacgccaggg
    17701 ttgttttacg ggcagaatac agagaggggc ttcccattat taacctcgtc agatgttgtg
    17761 ttcttgttag caaccgcgct ctgtgggcgg tttagtcagg ttcacattat cagtactgat
    17821 gcaaagggga ttgcctgcac ctgccaggtt gtttggcagg tgtgccagct tttcatacag
    17881 tggatgccct gaaaatagat gtacacatca tgcataatgt gacaacgtca caaaatttag
    17941 tgaaataaaa gggcaactat tcgccgttgc ccttcattca ccgattaatc gacaaaatca
    18001 ccgtgctgcc tggccaccag cgtcagaatt gaatacagcg ccaccggggt ttgatgctga
    18061 ttgaatacct ctaccgccca ttccaccaca cctgttggtt tttcttctgc gctacgctgt
    18121 tttttcagcg tcttgcgctt acaggtgaga cgcacctgga tggtatcgcc tggctttacg
    18181 ggttcgataa aacgcaagct ttccagcccg tagttagcaa tgaccggacc aacaccggca
    18241 tcgacaaaca gacccgcagc cgcagaaagc acaaaatacc catgcaccac ccgctcaccg
    18301 aaaatagatt cggcagcagc aatcttatcc atatgtgcat agaaatgatc gccgctgagg
    18361 caagcaaagt taacaatatc ggcctctgtc attgtgcggc ggggagtcaa caggctgtcg
    18421 cctggttgta gctcctcaaa atatttgcgg aacggatgaa tacgatcttc ttcgactttc
    18481 gcaccgcgca cccactgttt actgatagcg gcaagcatcg tcggactacc ctgaacagcg
    18541 gttcgctgca tgtaatgttt caccgctcgt aaaccgccta attcttcacc gcctcctgcg
    18601 cgaccaggcc caccatgtac cagttgtggc agtggggagc catgcccggt ggattctttt
    18661 gccgattctt cattgaggat ctgaattcgc ccatgcgtac gtgccgcgtc ggcaataaac
    18721 tgacgcgcaa tttgcggatc agccgtcacc agcgttcccg caaggctacc gccgcctgca
    18781 caagccagtt gcagagcatg ttgctggttt tgtgctggca ttagcgttgc gacagggcca
    18841 aaggcttctg ttgcatgtac cgccggtgtt tcatccggct gcggacagta caataaggtt
    18901 ggcgggaaga aggcacccgc cgcagataaa tccgcctgac caccgaggcg aatctcgcat
    18961 cctgcagcca gcaatgtgtt cactttttcc tgcacatcag cacgctgttc agcatttacc
    19021 agtgcgccca ttttcacgcc ttcttgtgca ggatcaccga ccacgacttt ctgtaatcgc
    19081 gcaaccagag catcactgac agcattaacc aatgtctgcg gcacaataat ccgccggatt
    19141 gccgtacatt tttgcccggc ttttgtggtc atctcacgca caacttcacg aataaacagc
    19201 gcaaactccg gttgatccgg ggtgatatct tcgcccagta cgcagcaatt cagggaatca
    19261 gcttccatgg tgaaggggat agatttggct acgatatttg gctgaactcg tagcatctgt
    19321 ccggtcgtcg cggaccccgt gaaagtcacc acatcctggc tgtccagatg atccaaaagg
    19381 tcgcccgcac taccgcagat cagactaatt gcgccttcgg gaacaagacc actatcgaca
    19441 attgatttca ccatcgcctg agtcagttgg gccgtcgcgg tagctggttt gatgatggct
    19501 ggcattccgc ccagccacgt tggtgccagc ttttccagca ttccccagca ggggaagtta
    19561 aaggcgttaa tatgcactgc cacgcctgac tttgaggtca gtacatggcg cgcggcaaat
    19621 ccaccttctt tcgataaggg gagcaattca tcttccggcc acagcgtatc gtcaggcagc
    19681 tcccggctac cgaggctggc gtaagtaaat aacgtcccaa tgccaccttc aatatcaacc
    19741 caactgtctg cccgcgttgc gcctgtttgc gcagaaagag catagaaacg ctctttttca
    19801 ctcagcagat gtttagcgac cgctttaagc atcgccgcac gttcgataaa ggtcatagcg
    19861 cgaagggctg gggcaccttt ttcaatggca aacaggcggg cagccgccat atcaagacct
    19921 tcactggtca cttcccataa cgcctcgccg ctaatagcgt ggtgaatcaa acggctacgg
    19981 ccccggccag actgccaggt accggataag aaactggcta actgctgcat cgctactctc
    20041 cagatgtttc acatttctgt tgctaatagt tgaatcgcga atcataaaaa gcaagggatc
    20101 ttttaatgaa atgttaacta tgcgatctgt atagcaactg cggaaaacat taatgcactg
    20161 ataaataatg atttataaaa agagggtgcg aaatccgtca cagttcaagc atacaaaatt
    20221 tgtgatttta gttaaccatt gtgtaacttt cataaaacaa tgtgattcgt gtttttaatt
    20281 aattcacgaa aactggaatc gtaaaggtga tgacgtgacc caagaagaac gctttgagca
    20341 acggatagcc caggaaacgg ctatcgagcc acaggactgg atgcccgatg cttaccgaaa
    20401 gacattgatc cgccagattg ggcagcatgc gcactccgag attgttggta tgttgcctga
    20461 aggtaactgg atcactcgcg caccaacctt gcggcgtaaa gccattctgt tagccaaagt
    20521 gcaggatgaa gccggtcatg gtctgtatct ctatagcgcc gccgaaacac tgggctgtgc
    20581 cagagaagac atctaccaaa aaatgctcga cggacggatg aaatattcct ccatctttaa
    20641 ttatccgaca ttgagttggg ctgatatcgg cgttatcggc tggctggtgg atggcgcagc
    20701 gatcgtcaat caggtggcgt tatgccgaac ttcttatggc ccgtatgcca gagcaatggt
    20761 gaaaatctgc aaagaagaga gttttcacca gcgtcagggg tttgaagcct gcatggcact
    20821 ggcgcagggc agcgaagctc aaaagcagat gttgcaagac gccattaacc gtttctggtg
    20881 gccagcctta atgatgttcg ggccaaacga tgataactcg ccaaacagcg ccagaagtct
    20941 cgcctggaaa atcaaacgtt tcaccaacga cgaactccgc cagcgtttcg tggacaacac
    21001 cgttccacag gttgaaatgc tcggtatgac cgttcctgac ccggatctgc attttgacac
    21061 tgaaagcggt cactaccgct ttggtgagat cgactggcag gagtttaacg aagtaattaa
    21121 cggtcgcgga atttgtaatc aggagcggct tgacgccaaa cgtaaagcct ggaaagaagg
    21181 tacctgggta cgggaagcag cgctggccca tgcacaaaaa caacatgccc gtaaggtcgc
    21241 ataaggagat tcaaaatgag taatgtttac tggccgttat acgaagtttt cgtgcgtggc
    21301 aaacagggct tatcacaccg ccatgttggc agtttacatg ctgccgatga gcggatggca
    21361 ctggaaaatg cccgtgatgc ttacacccgt cgtagcgaag gatgttcaat ttgggtggtg
    21421 aaggcgagtg aaattgttgc ctcgcaaccg gaagaacgcg gtgaattttt tgatccggct
    21481 gaaagcaagg tctatcgcca tccaacgttt tacaccatcc ctgatggcat tgagcacatg
    21541 tgaggtcgga aatgaatcag ttaacggctt acaccttgcg cctgggcgat aactgcctgg
    21601 tgctctccca gcggttgggt gaatggtgcg gtcatgcacc ggaactggaa atcgatctcg
    21661 cactggcaaa tattggactc gatttattag gccaggcacg caacttctta tcgtatgccg
    21721 ctgaattagc gggagaaggc gatgaagata ccctggcctt cacccgagac gagcgccagt
    21781 tcagcaactt attgttggtt gaacagccaa acggcaattt tgccgacacc attgcacgcc
    21841 agtatttcat cgatgcatgg catgtggcgc tctttacccg tctgatggag agccgtgatc
    21901 cgcaactggc ggcgatttct gccaaagcaa ttaaagaagc gcgttatcac ctgcgtttta
    21961 gtcgtggctg gctggagcga ctgggcaatg gtactgacgt atcagggcaa aagatgcagc
    22021 aggccatcaa caagttgtgg cgttttaccg ccgaactgtt cgatgccgac gagattgata
    22081 ttgcactgag tgaagagggt attgcggttg atccacgcac tttacgcgca gcgtgggaag
    22141 ccgaagtttt tgccgggatc aacgaagcca cattgaacgt accgcaagag caggcgtatc
    22201 gcactggcgg taaaaaagga ctgcataccg aacaccttgg acccatgctg gcagaaatgc
    22261 agtatctcca gcgtgtcttg cccggtcagc aatggtaaca gaggagatgg gtatgcaacg
    22321 tctggccacc attgcaccgc cacaggttca tgagatatgg gcgctactca gccagatccc
    22381 ggacccggag atcccggtgc tgaccattac cgatttaggc atggtgcgta atgtgacaca
    22441 gatgggagaa ggatgggtga tcggctttac gccgacttat tccggttgtc cggcaacgga
    22501 acatttgatt ggcgcgatac gtgaggcaat gacaacccac gggtttaccc ccgttcaggt
    22561 tgtgctgcaa ctcgacccgg catggaccac cgactggatg acccccgatg cccgtgagcg
    22621 tctgcgacag tatggcatta gcccgcccgc cggacacagt tgccatgccc atttgccgcc
    22681 agaagtacgt tgcccgcgct gcgccagcgt ccataccaca cttatcagtg aatttggttc
    22741 cacggcctgc aaagcattgt atcgctgcga tagttgccgc gaacctttcg attatttcaa
    22801 atgtatttga ggatgccatg acaacgtttc attccttaac ggtggcaaaa gtggagccgg
    22861 aaacccgtga tgcggtgacc attacctttg cggtgcccca gcctttgcag gaggcgtatc
    22921 gctttcgccc cggtcaacat ttgaccttaa aagccagctt tgatggtgaa gaattacgcc
    22981 gttgttactc catttgccgc agctatctgc ctggcgaaat tagtgtggcg gtgaaagcca
    23041 ttgaaggcgg acgtttctcc cgctatgccc gcgaacacat ccgccagggt atgacgctgg
    23101 aggtcatggt gccgcagggg catttcggct atcagccaca ggccgaacgc cagggccgct
    23161 atctggctat tgcagcagga tcaggtatta cgccaatgct ggcgattatc gccaccactt
    23221 tacaaaccga gcctgaaagt cagttcaccc tgatctacgg taaccgtacc agccagagca
    23281 tgatgtttcg ccaggcactg gcagacctga aagacaaata tcctcagcgt ttacagttgt
    23341 tgtgcatttt cagtcaggaa accctcgaca gcgatctgct tcacgggcgt attgacggtg
    23401 aaaaattaca gtcacttggg gcctcgctca ttaattttcg tctttatgat gaggcattta
    23461 tttgtggtcc ggcggcgatg atggatgaga cggaagccgc cttaaaagca ctgggaatgc
    23521 cagataaaac cattcatctg gagcggttta atacgcctgg cacgcgcgtc aaacgtagcg
    23581 ttaacgtgca aagtgacgga caaaaagtga ctgtacgtca ggatgggcgg gatcgggaaa
    23641 tcgtgcttaa tgccgacgat gaaagcattc tcgatgcggc attgcgccag ggggctgatc
    23701 tgccctatgc ctgcaaaggc ggcgtctgtg cgacctgcaa atgcaaagtg ctgcgtggca
    23761 aagtggcgat ggaaaccaat tacagtctgg aaccggatga actggccgca ggctatgtgt
    23821 tgagttgcca ggcactgccg ctgaccagcg atgtggtggt tgactttgac gcgaagggga
    23881 tggcatgagc gaactgatcg tcagccgtca gcaacaagta ttgttgctga cccttaaccg
    23941 tcccgccgca cgtaatgcgc taaataatgc ccttctgacg caactggtaa atgaactgga
    24001 agctgcggct accgatagca gcatttcggt ctgtgtgatt accggtaatg cacgcttttt
    24061 tgccgctggg gccgatctca acgaaatggc agaaaaagat ctcgcggcca ccttaaacga
    24121 tacacgcccg cagctatggg cgcgattgca ggccttcaac aaacctctca tcgcagccgt
    24181 caacggttac gcgcttggtg cgggttgcga actggcattg ttgtgcgatg tggtggttgc
    24241 cggagagaac gcgcgttttg gtttgccgga aatcactctc ggcatcatgc caggcgcagg
    24301 aggaacgcaa cgtttaatcc gtagtgtcgg taaatcgtta gccagcaaaa tggtgctgag
    24361 cggagaaagt atcaccgctc agcaagcaca gcaggccggg ctggttagcg acgtcttccc
    24421 cagcgattta accctcgaat acgccttaca gctggcgtcg aaaatggcac gtcactcgcc
    24481 gctggcctta caagcggcaa agcaagcgct gcgccagtcg caggaagtgg ctttgcaagc
    24541 cggacttgcc caggagcgac agttattcac cttgctggcg gcaacagaag atcgtcatga
    24601 aggcatctcc gctttcttac aaaaacgcac gcccgacttt aaaggacgct aatgatggaa
    24661 ttcatcctca gtcatgtaga aaagggcgtg atgacactaa cgctcaaccg cccggaacgc
    24721 ctgaacagtt ttaatgatga gatgcacgca caactggcag agtgcctgaa acaggtcgag
    24781 cgcgacgaca ctatccgttg cctgttactt acaggtgccg ggcgcggatt ttgtgctggt
    24841 caggatctta acgatcgtaa cgttgatccc acaggccccg caccggattt agggatgtca
    24901 gttgaacgtt tctataaccc actggtacgt cgcctggcaa aactgccaaa accggtgatc
    24961 tgtgcagtca atggcgtggc ggcaggggct ggcgcaacac tggcactggg atgcgacatc
    25021 gttattgctg cccgttcagc aaaattcgtc atggcgttta gtaagttagg tttagtaccc
    25081 gattgcggtg gaacctggtt actgccacgc gttgctgggc gagcgcgcgc catggggctg
    25141 gcactgctgg ggaatcaact gagtgctgaa caggcgcacg aatgggggat gatctggcag
    25201 gttgttgatg atgaaacgct ggcagatacc gcgcaacagc tggcacggca tctggcgaca
    25261 caaccgacat ttggtcttgg acttatcaag caagcgataa atagcgctga aaccaatact
    25321 ctcgatacgc aactggatct ggaatgcgac tatcagcgac ttgccggacg gagcgcagat
    25381 tatcgtgaag gtgtcagtgc gttcctggct aaacgctcac cgcagttcac ggggaaatag
    25441 catgatgata aatgtgcaaa ctgtggcagt gattgggagc ggcaccatgg gggctggcat
    25501 tgctgaagtt gccgccagtc atggacatca ggttttactg tatgacattt ctgctgaagc
    25561 gctgacccgc gcaatcgacg ggatacacgc gcggctaaat tcacgcgtga cgcggggaaa
    25621 actgactgct gaaacctgtg aacgcacatt gaaacgcctg atcccggtga ccgatattca
    25681 cgcgctggca gctgcggacc tggtcattga agcggcgtct gaacgtctgg aagtcaaaaa
    25741 agcgctcttt gcacagctgg cggaagtttg cccgccacaa acgctattga ccactaacac
    25801 ttcgtcaatc tctataaccg cgattgctgc ggaggtaaaa aatcctgaac gtgttgcggg
    25861 gctgcatttt tttaacccgg caccggtgat gaagttggtg gaggtggtca gtgggctggc
    25921 aacggcagcg gaagttgttg agcagttgtg tgaactaacg ttgagttggg gtaagcagcc
    25981 tgtgcgctgt cattcgaccc ctggatttat cgttaaccgt gtggcgcgtc cttattattc
    26041 cgaggcctgg cgggcactgg aagagcaggt tgctgcacca gaagtgattg acgctgcact
    26101 tcgcgatggc gctggtttcc cgatggggcc gctggaatta accgatctga ttggtcagga
    26161 cgtcaatttt gctgtcacct gttcggtgtt taacgctttc tggcaggagc gtcgtttttt
    26221 accttcgctg gtgcaacagg aactggtgat tggtggacgg ttgggcaaga aaagtgggct
    26281 gggcgtgtac gactggcgcg cggaacgtga ggcagttgtt ggcctagaag cggtaagcga
    26341 cagttttagc ccaatgaaag tagaaaagaa aagtgacggt gtcacggaaa ttgacgatgt
    26401 tttattgatt gagacacaag gcgagacggc acaggcgctg gcaatacgac tggcacgccc
    26461 ggtggtagtg gtcgacaaaa tggcgggcaa ggtggtgacc attgctgcgg cagcggtgaa
    26521 cccggactca gcgacccgca aggccattta ttacctgcaa cagcagggca aaacagtgct
    26581 gcaaattgca gattacccag gaatgctgat ttggcgaacg gtagcaatga tcatcaatga
    26641 agcccttgat gcgctgcaaa aaggcgtggc ctctgaacag gatatcgata ccgccatgcg
    26701 tcttggggtg aattatccat atggcccgct tgcctgggga gcgcaacttg gctggcagcg
    26761 aatattaagg ctcctggaaa atctacaaca tcactatggc gaagaacgct atcgcccatg
    26821 ttcattgctg cgccaacgag cgcttctgga gagcggttat gagtcataag gcctggcaaa
    26881 atgcccatgc aatgtatgag aacgatgcct gcgccaaagc gcttggcatc gacattatct
    26941 caatggatga aggctttgct gtagtgacca tgaccgtcac tgcacaaatg cttaatggtc
    27001 atcaaagttg ccacggcggg cagctatttt cactggctga tactgccttt gcctacgctt
    27061 gcaatagcca ggggttggca gctgtcgctt ctgcctgcac gattgatttt ttacgtccag
    27121 gctttgccgg agacacctta actgcgactg cgcaggtacg tcatcagggc aagcaaaccg
    27181 gtgtttacga catcgaaatt gttaaccaac aacaaaaaac ggttgcgctg tttcgcggta
    27241 aatctcaccg catcggcggc accattacag gagaagcctg atgcgtgaag cctttatctg
    27301 tgacggaatt cgtacgccaa ttggtcgcta cggcggggca ttatcaggtg ttcgggctga
    27361 cgatctggct gctatccctt tgcgggagct gctggtgcga aacccgcgtc tcgatgcgga
    27421 gtgtatcgat gatgtgatcc tcggctgtgc taatcaggcg ggagaagaca accgtaacgt
    27481 agcccggatg gcgactttac tggcggggct gccgcagagt gtttccggca caaccattaa
    27541 ccgcttgtgt ggttccgggc tggacgcact ggggttcgcc gcacgggcga ttaaagcggg
    27601 cgatggcgat ttgctgatcg ccggtggcgt ggagtcaatg tctcgggcac cgtttgttat
    27661 gggcaaggca accagtgcat tttctcgtca ggctgagatg tttgatacca ctattggctg
    27721 gcgatttgtg aacccgctca tggctcaaca atttggaact gacagcatgc cggaaacggc
    27781 agagaatgta gctgaactgt taaaaatctc gcgagaagat caagatagtt ttgcgctacg
    27841 cagtcagcaa cgtacggcaa aagcgcaatc ctcaggcatt ctggctgagg agattgttcc
    27901 ggttgtgttg aaaaacaaga aaggcgttgt aacagaaata caacatgatg agcatctgcg
    27961 cccggaaacg acgctggaac agttacgtgg gttaaaagca ccatttcgtg ccaatggggt
    28021 gattaccgca ggcaatgcct ccggggtgaa tgacggagcc gctgcgttga ttattgccag
    28081 tgaacagatg gcagcagcgc aaggactgac gccgcgagcg cgtatcgtag ccatggcaac
    28141 cgccggggtg gaaccgcgcc tgatggggct tggtccggtg cctgcaactc gccgggtgct
    28201 ggaacgtgcg gggctgagta ttcacgatat ggacgtgatt gaactgaacg aagcgttcgc
    28261 ggcccaggcg ttgggtgtac tacgcgaatt ggggctgcct gatgatgccc cacatgttaa
    28321 ccccaacgga ggcgctatcg ccttaggcca tccgttggga atgagtggtg cccgcctggc
    28381 actggctgcc agccatgagc tgcatcggcg taacggtcgt tacgcattat gcaccatgtg
    28441 catcggtgtc ggtcagggca tcgccatgat tctggagcgt gtttgagcat atcaacctgc
    28501 gagtacccta caatgataac caatacaaag cttgacccga ttgaaaccgc gtctgttgat
    28561 gagttacagg cgttgcaaac acagcgtctg aaatggacgc tcaaacacgc gtatgaaaat
    28621 gtcccgatgt atcggcgcaa attcgacgca gcaggcgtac atcctgatga tttcagggaa
    28681 ctttcagacc tgcgtaaatt tccctgtacc accaaacagg atctgcgcga caactatccc
    28741 tttgacacct ttgccgtgcc gatggaacaa gtggtgcgca ttcatgcttc ttcgggaacc
    28801 acaggtaaac cgacagttgt cggttatacg caaaacgata ttgataactg ggccaatatt
    28861 gtagcgcgtt ctttgcgtgc ggcagggggc tcgcccaaag acaaaattca tgttgcctat
    28921 ggttacggcc tgtttactgg tgggctgggc gcgcactatg gtgccgaacg tctgggcgct
    28981 acggtgatcc cgatgtctgg cgggcagacg gaaaaacaag cgcaactgat ccgcgatttt
    29041 caaccagata tgatcatggt tacgccatct tattgcctta acctgattga agagctggag
    29101 cggcagttgg gcggtgatgc cagcggttgc tcgctgcggg ttggcgtgtt tggtgctgag
    29161 ccgtggacac aggccatgcg taaagagatt gaacggcgtc tggggatcac cgcactggat
    29221 atttatggcc tgtcagaagt gatggggccg ggggtggcga tggagtgtct ggaaactacc
    29281 gacggtccaa ctatttggga agatcatttc tatcctgaaa ttgttaatcc tcatgacggc
    29341 acaccgcttg ccgatggtga acatggcgaa ctgttattca ccacgctgac caaagaagca
    29401 ttgccggtca ttcgttaccg cacgcgtgat ttaacccgac tgttaccagg aacggcgcgg
    29461 actatgcgcc gcatggatcg catcagcgga cgcagcgatg acatgttgat tattcgcggt
    29521 gtaaatgtct ttccgtcaca actggaagaa gagattgtca aattcgaaca tttatcgccg
    29581 cattaccaac tggaggtgaa ccgccggggg catcttgatt cactttctgt gaaagtggag
    29641 ttgaaagaaa gtagcctgac attgacgcat gagcagcgtt gccaggtatg ccaccagctg
    29701 cgccatcgga ttaagtcgat ggtggggatc tctaccgatg tgatgatcgt taactgtggc
    29761 agtatcccgc gttcagaagg caaggcgtgt cgggtgtttg atctgcgcaa tattgttggt
    29821 gcctgacgtg tcgtctggcc ctggtgaggt aaagcgccag ggccagaagt cgatacgacc
    29881 tgtgctatga ttcataaatc acaacaataa caacagactg aatcgaatga gtaaacttga
    29941 tacttttatc caacatgctg taaacgctgt tcctgtcagt ggcacatctt tgatctcctc
    30001 tctgtatggt gattctcttt cccatcgtgg tggtgaaatc tggctgggta gtctggctgc
    30061 tttgctggaa gggctgggat ttggtgagcg tttcgtgcgc actgctttgt ttcgtcttaa
    30121 taaagaaggc tggctggatg tttcccgcat cgggcgacgc agtttctata gcctcagtga
    30181 taaaggcttg cgcctgacgc gacgggcaga aagtaaaatt tatcgcgcag agcaacccgc
    30241 atgggatggt aaatggctcc tgttgctctc ggaaggttta gataaagcga cgctggctga
    30301 tgtcaaaaag cagttgatct ggcaaggttt tggtgcactg gcgcccagcc tgatggcatc
    30361 gccgtcgcaa aaactggccg atgtacagac acttttgcat gaagcgggtg tggcggataa
    30421 cgtgatttgt tttgaagcgc aaataccact ggcgctttct cgtgcagcac tgcgtgccag
    30481 agtagaagag tgctggcatt taactgaaca aaatgccatg tacgaaacct ttattcagtc
    30541 attccgcccg ttggtgcagc tgttaaaaga ggcagcagac gagttaaccc cggagcgtgc
    30601 atttcatatt cagcttttac tgatccattt ttatcgccgt gtcgtcctta aagacccttt
    30661 gttgccggag gagttgcttc cggctcactg ggcagggcat acggcgcgtc agctgtgtat
    30721 caacatttat cagcgcgtag cgcctgctgc tttagcgttc gttagtgaaa aaggtgaaac
    30781 ctcggtcggt gaactgcctt cgccgggtag cctgtatttt caacgttttg gcggtttgaa
    30841 tattgaacag gaggcgttat gccaatttat cagatagacg gtctgactcc ggttgtgcca
    30901 gaagagagtt ttgtccatcc gacagcggta ttgatcggcg atgttattct cggcaagggt
    30961 gtttacgttg ggccaaatgc cagcctgcgt ggcgattttg gtcgtatcgt ggtgaaagat
    31021 ggcgcgaaca ttcaggataa ttgcgttatg cacggttttc ccgagcagga tactgtcgtt
    31081 gaagaagatg ggcatatggg tcatagcgct atccttcacg gctgcattat ccgccgcaat
    31141 gcattagtgg gaatgaacgc ggtagtgatg gatggtgcgg tgattggcga gaacagcatt
    31201 gttggcgcat ccgcatttgt gaaagccaaa gcagaaatgc ctgccaatta cctgattgtc
    31261 ggcagcccgg cgaaactgat tcgtgagctt agtgagcagg agctggcatg gaaaaagcag
    31321 ggtacgcatg agtatcaggt gctggtgaca cgctgtaagc agacgttaca tcaagtcgaa
    31381 ccattgcggg aagttgaacc tggcaggaaa cgcctggtat ttgatgagaa tctgcgaccg
    31441 aaacagtaac gtccagatac tgaacgttct aatttttagc atgtgatacc taaaccgcaa
    31501 cgctgataca ggttgcggtt tttttattgc cgaatgcggc gctttacgcg ttttgttttg
    31561 gtgtctttca ggacaataga gcaactcatc cagtaatctt gtttacgcct tcgcattatt
    31621 tatctctttt cgtttctata ctgatttttc tcaatccgtt ttattacagg gcagggtgcg
    31681 atgagcagca atacatttac tctcggtaca aaatccgtta accgtcttgg ttatggcgcg
    31741 atgcaactgg caggtcctgg ggtttttggt cccccaagag atcgccacgt cgctataacc
    31801 gtgctgcgcg aggcgctggc attgggcgtc aatcacattg ataccagcga cttttatggt
    31861 ccgcacgtca ccaatcagat tatccgcgaa gcgctttatc cttactctga cgacctgaca
    31921 attgtcacta aaattggtgc gcggcgtgga gaggacgcat cctggttgcc cgcattttct
    31981 ccggcagagc tgcaaaaagc ggtgcacgat aatctacgta atctcgggct ggacgtactg
    32041 gatgtggtta acttgcgcat tatgatgggg gatggtcatg gcccagcgga aggatcgatt
    32101 gaagccagcc tgaccgtgct ggcagagatg caacaacaag gcctggtaaa acatattggc
    32161 ctaagcaacg tcacaccgac gcaggttgca gaggcgcgca agattgccga aatcgtctgt
    32221 gtgcagaacg aatacaacat tgctcatcgt gctgatgacg caatgattga tgctttggct
    32281 cgtgacggca ttgcctacgt gccgttcttc ccgctcgggg gctttacacc gctgcaatcc
    32341 tctacgctgt cggatgttgc tgcgagcctg ggtgcaacac ccatgcaggt ggcgctggcg
    32401 tggctgttac aacgttcacc gaatattttg ctgatcccag ggacgtcttc tgttgcgcat
    32461 ttacgggaga atatggctgc tgaaaaattg catctttctg aggaagtgtt gtctacgttg
    32521 gatggtattt cgcgagaata acgaatatac aaaagggaaa gatgcatttc ccttttgttt
    32581 cttttttaat ggcatggagt gcatatgttt aaggccagga tttgcggctg gataggttta
    32641 cttcccctgt ttatgctgag tcttccagta caggcggaac ttcgatgtgt tgcaaataca
    32701 gttgatattg aaccattttt ttctgcggct accgctgaag ataaacaaca agttgaacaa
    32761 gctatcaaca gtagcgtgaa tcttgtcccc ttcggtttat ctgcatcgga ctggaaagtg
    32821 catcgtggcg atttagtggt agaaggtaat atagagagta atcaaaaatt gattgttctt
    32881 ggtaatttga cagtcaaagg taatatttcc actttctctc tttctaatcc atgggttatt
    32941 ctcggtaacg tgacggcaac gaatatagtt acggattcac cactgttaat taccggttcg
    33001 ataaatgcaa gtggactggt atttatcgac tcatattacg ataatccgtc ttcgattaag
    33061 gggagtatta atgcgcgtgg aatatttatc aatgacataa ttgcacctgt tgttgcgtct
    33121 tcgacaaata gtgaattcat ggtccgtgcg agtgacaaaa atgacactga aaatgtcaaa
    33181 aaagcgctga tgataataaa tcctgatgca tattattggg gtctaataaa tgatgaagat
    33241 gctctgaaag aaatttttaa gcgaagcaat attcgcatgg cagggaatgt ctgtaatcag
    33301 atgaaaaaag aagcgctgtt tcgccctaag ccttctcctg agttagtgca ggaattgcaa
    33361 atgctggatg aaggcaacgt tgctgcattt gaaggacgag atattgcgac atttgatctt
    33421 gccataatgc gaactctccc aaggcttaaa ggaatttcag ctaacctacg caaacaactt
    33481 attaatagca atgatgaaca aacgattgaa agtatggcga gatatatgcc tgacaatgag
    33541 attctggagt tgaccgatca gcaattgggt taccagcctg ttgttctggg gttgctcgac
    33601 cgtgaaccgc tctctgtcga aataatgacg cgaatgagtc gtctacctga tggtgtcggt
    33661 ccgttgaatc ttgcgctacg tgaaaatctc cctctggata tcgtaatgac tctggcgaaa
    33721 agagattggg atatgatcat tcaggagctt tataaagatg cgtggttatt gcctgaatcc
    33781 attattgatg gctatatccg cagtgatgat tcctctattc gtcaggtcgg tgctggagga
    33841 caactcacct acaatcaggc aatgcagttg gcgaacgatt catcaaacaa tgttgtcaca
    33901 agcttagcgt tcaagctggc agagatgaaa caccatggtc aattattgcg gatgacgcca
    33961 caagagagtg acaaagttgc agcctattta taccaaaaat tcgagaatga cgatgatcta
    34021 atacgtgtgt tatttttagc attgccagat aacttacagt ttaattttgt taaaaggatg
    34081 gagaaaaaat cccctgccta cttttgctgt cgggatatgc aggtaattca ctctgacgct
    34141 gctctacaac ggttattgac acgtttcaac gatcctgagg ggtggagtaa tctggcgaaa
    34201 aatcagtatc tgagcacgtc gatgaaacaa aaaatttggc aacgtgcttt atcgcatcgg
    34261 aaaaataatc cgaaagcaga ttcagctgcg tatgaaacca gcgctgatat gattttgtct
    34321 gagcttatca gccacggtga agttgatgat cagatgctat taaatgccac ctccctgata
    34381 cgtttggaag actgggactt tttagagagt gcattagtta gttgggataa tttacccgct
    34441 gttgtcctca aggaattaca gcaaaatacg ccacgcaatg atatttgggc gaagtttttt
    34501 ctgaggcagg aaaacagctc ccgtgcgcag gttgatgaag cattacgcgt ctattatgca
    34561 ctcgaccccg atgcgttagc acaactggat gtactggcaa aacaaccgga tcgtatatgg
    34621 tggagtacac tggcgaaaag caatctcaca tttttcaagt tcggcgcact taacaaccgc
    34681 cacacaccgc ctgcagtact ggcggcagaa attgatcccg agtggtggat tgtggcgatg
    34741 aataatcccc gttttccagt tgatgtatta aaggcgaggc tgaaacgtga tcctttgctg
    34801 gcgttagagc ttgttaaccc tgaactggat ttagtccgcc agctggcgct taacggtaag
    34861 acgcgcgcaa tacgggaaca agcgatgaga aaacttgatg agttgtattg atccacaacg
    34921 taatatttct taaccctttg attaattggg gataattatt cctgacagtg agtccccaat
    34981 accttgatat attctgaatt tttaatgaag cggcgtgttg cgatatctcc gtcaggggaa
    35041 ttgatgcacc atagcgcaaa ccgaattatc aaggattgat aatgacgctc taccagataa
    35101 aaccgctctt tcagtcgctg ttaaggccga cgatgttttg gctttacaag caccacgtta
    35161 cagcgaatca catcactctt gctgcactgg cgctttctct tcttaccgga ttgctgttga
    35221 tgttggtggc acaacccatc ctctttatgc tattgcccat cgtgcttttt atccgtatgg
    35281 cgctcaatgc gctggatggc atgttggcgc gtgagtgcaa tcagcaaaca cggcttgggg
    35341 caattttgaa tgagactggt gatgttattt ccgatattgc gctctattta ccatttttat
    35401 ttttaccgga aagtaacgca tcactcgtga tactcatgtt attttgcacc atattgaccg
    35461 agttttgcgg tttactcgcg cagacgatta acggtgttcg cagttatgcc ggtccatttg
    35521 gcaaaagcga tcgcgcgtta atatttggtc tgtggggtct ggccgttgcc atttatccac
    35581 agtggatgca gtggaataat cttttatgga gcattgcttc aattctgctt ctctggactg
    35641 cgattaatcg ttgtcggagt gtgcttctta tgagcgctga aagataatgc tggaaaaatc
    35701 tctggcaaca cttttcgcgt tgttaatttt agcaacgctg ataaaccatt ttctggtatg
    35761 gcggttaccg gagagaaaag aggatgaagt tacattacgt attcgtacct ggtggggcat
    35821 cgtcatttgt ttttcactgg tgatttcagg tccacgctgg atgacgttga cgttttttgc
    35881 gctgataagt tttctggcat tgaaagaata ttgtacgctt atatctgtac attttccgcg
    35941 gtggttatat tgggttattc ctcttaacta tttgtttatc ggttttaatt gctttgagct
    36001 gtatctatta tttatacctt tggctgggtt tctaatatta gccaccgggc aagtttttgt
    36061 gggggacccc tccggttttc tgcataccgt gagcgccatt ttttggggct ggataatgac
    36121 cgttttcgcc ttgagtcatg ccgcctggtt attaatgttg ccaaccacaa atatccaggg
    36181 cggggcgtta ctggtgttat ttcttttggc attaaccgag tcaaacgata ttgcacacta
    36241 tttatgggga aaatcctgcg gcagaagaaa agtggtcccc aaagtcagcc cgggaaaaac
    36301 gctggaaggt ctggtggggg gcgtcatcac caccatgatt gcgtcactga ttattggacc
    36361 gttgctgaca ccgctaaata cattacaggc attattagcg ggtttgttaa ttggtattag
    36421 tggtttttgc ggcgatgtcg tgatgtcagc catcaaacga gatattggtg ttaaagatag
    36481 tggaaaacta ttaccaggac atggcggact ccttgacagg attgactcat taattttcac
    36541 cgctccggta tttttttatt ttattcgcta cagctgttac tgaaggaaaa tagagaaaat
    36601 ggaaaattca cgcatccctg gggaacattt ttttaccacc agtgataata cagcgttgtt
    36661 ttatcggcac tggcccgctt tacagcccgg ggcgaaaaag gtcatcgtct tatttcatcg
    36721 gggtcatgaa cattctggtc gtctacaaca tctcgttgat gaactggcga tgccagatac
    36781 tgctttttat gcatgggatg cccgggggca tggaaaaact tcggggccgc gtggttatag
    36841 cccatctctt gcgcgttcag tgcaggatgt cgatgaattt gtccgttttg ctgccagcga
    36901 cagccaggtt ggactggaag aggtggttgt gatcgcgcaa agcgtcggcg cagtgctggt
    36961 tgccacatgg gttcatgatt atgcgcctgc aattcgcggg ctggtgctgg cttctccggc
    37021 ctttaaggtt aaattgtatg tgccgctggc acgtcctgcg ctggcgttat ggcatcgtct
    37081 gcgtggtctg ttttttatta attcctatgt gaaaggacgc tatttgaccc acgatcggca
    37141 acgggtggcg agtttcaata atgatccgct gatcacacgg gcgattgccg tcaatatctt
    37201 gctcgatctc tacaaaacgt ctgaacgtat tattagagat gcggcggcga ttacgctccc
    37261 cacgcaactt ctgatatcag gcgatgacta tgtggtgcat cgccaaccgc agattgattt
    37321 ttatcagaga ttacgtagcc ctctgaaaga gctgcatctg ctgccaggct tttatcacga
    37381 cacgttgggt gaagagaaca gggcgcaggc atttgaaaaa atgcaaagct ttattagtcg
    37441 tttatatgct aacaagtcac aaaaatttga ttatcagcat gaagaccgca ctggaccatc
    37501 agcggatcgc tggcggctcc tttcaggtgg acccgtgcca ttatcgccgg ttgatttggc
    37561 gtatcgcttt atgcgaaagg cgatgaaatt gttcggggcg cactctgcgg gcctgcatct
    37621 cggaatgagc accggctttg attcaggcag ttccctggat tatgtctatc aaaatcaacc
    37681 gcaaggcagt aacgcattcg ggcgcttaat tgacaaaatc tacctgaaca gtgttggctg
    37741 gcgcggtatt cgccagcgta aaacccattt acaaatactg attaaacaag ccgttgccga
    37801 tctccacgcc aaaggtttag ccgtccgcgt ggttgacatt gccgcagggc atgggcgcta
    37861 tgtactggat gcgctggcaa acgagcctgc cgtaagcgat attttgttac gtgattacag
    37921 tgagttaaat gttgcacagg ggcaagcgat gattgcccaa cggggaatgt ctgggcgggt
    37981 gcgttttgaa cagggcgatg cgtttaaccc ggaggaactc agcgcgttaa ctccgcggcc
    38041 tacgctggcg attgtctctg gcctgtatga gctttttccc gaaaatgagc aggtaaaaaa
    38101 ctcactcgca ggtcttgcca atgccatcga accgggcggc attctcatct acaccgggca
    38161 gccgtggcac cctcaactgg agatgattgc cggggtgtta accagtcata aagatggtaa
    38221 accgtgggta atgcgcgtgc gttcgcaagg ggagatggat tcactcgtgc gtgatgccgg
    38281 atttgataaa tgcacacaac ggattgatga gtggggtatt tttacggttt cgatggcggt
    38341 gcgtcgtgat aactgaacgt cggaacgtat tgctacaagg cgctggctgg ttattgttgc
    38401 tggccccgtt tttcttcttc acctatggat ctcttaatca gttcaccgcg gttcaggacc
    38461 ttaacagcca tgatatcccc agtcaggtat tcggttggga aacggcgatc ccttttcttc
    38521 cctggactat tgttccttac tggagtctgg atcttttata tggattttcg ctgttcgttt
    38581 gtagcacgac attcgaacag cgccgacttg tccaccggct tattctggca acggtaatgg
    38641 cctgctgcgg ttttttgctc tatccgctga agtttagttt tatccgtcct gaagtgagtg
    38701 gggtgacggg atggctattt tcgcaacttg aactgtttga tctgccttat aaccagtctc
    38761 cttcgctgca tattattctc tgctggctac tttggcgtca ctttcgtcag catctggctg
    38821 agaggtggcg taaagtctgc ggcggatggt ttttactcat cgctatttct actctgacga
    38881 cctggcagca tcattttatt gatgtcatca cagggctggc ggtaggtatg ttgattgact
    38941 ggatggtgcc cgtcgaccgt cgttggaatt atcagaaacc tgatcaacgt cgaatcaaaa
    39001 tagcactgcc ctatgtcgta ggcgcgggct cgtgcattgt attgatggag ctaatgatga
    39061 tgattcagtt atggtggtca gtctggttat gttggccagt attatcgcta ctcataattg
    39121 gccgtgggta cggtgggctt ggcgcgataa caacagggaa agatagtcag gggaaactac
    39181 cgcccgccgt ttactggctg acattgccct gccgcatcgg gatgtggctg tctatgcgtt
    39241 ggttttgtcg tcgcctggag ccggtgagca aaatgactgc tggtgtttat ttaggggcgt
    39301 ttccacgaca tattccggca cagaatgcgg ttctggacgt cacctttgaa ttccctcgcg
    39361 gacgagcgac aaaagatcga ctctatttct gtgtaccgat gctggatctg gtggttccgg
    39421 aagaggggga gctccgacag gccgtggcga tgctggaaac attacgcgaa gagcaaggca
    39481 gcgttctggt ccattgcgcg ttgggattat cgcgcagtgc gctggtagtg gcggcatggt
    39541 tgttatgtta cggacactgt aaaaccgttg atgaagcgat tagttatatt cgagccagac
    39601 gttcgcatat tgtgcttaag gaagatcaca aagcgatgct gaaattatgg gaaaacaggt
    39661 aagtggattg agatgtggac tgaactacag tccacatcaa gatcgtgtcc ggttatgcag
    39721 caacaatgct gtcgatggcc gctttcgcgt cagactgcgc tttcgctgcc atttccggac
    39781 cgtatgcgat cccttcggcg aagacaaatt tcacatcggt aatgccgata aagccgagga
    39841 acgtggacag atacggcgtc accaggtccg ttggtccatc tttgtggatc ccaccgcggc
    39901 tggtaataac gatggctttt ttacccgtta ccagaccttc cggaccgttc tcggtatagc
    39961 ggaaagtaac gcctgcgcgt gcaaccaggt caaaatagtt tttcaactga gttgagatgt
    40021 tgaagttata catcggtgcc gcaataacga taacgtcgtg ggctttcagc tcggcaatca
    40081 gctcatcgga aagcgccaga gcttcctgct gacgcggagt cagcggcgca tcgctcggac
    40141 gcagtgcacc aaccagttcg ccatccagta ccggaatcgg atttgcagcc aggtcgcgaa
    40201 cggtgatttc atcagcggag tgcttttcgc gccattgttc aacaaaataa tcggacaact
    40261 gattagactg agagtaccct gccaggatgc tggatttaag aactaatacc ttgctcatgg
    40321 tgtttcctta tagatgtttg aatgggcgat gccccgttgc ttgctgacac tttattcaca
    40381 atcctgccac agagatagcg caataaatcg aagcctatgt tcgaatttat tgaacaacgc
    40441 atagaaagcc gcgatgtggt actctatatc tatcatttaa aagaaaatta atcaggcaga
    40501 ctactgccca ctaacgttat gacagaacaa caaaaattga cctttacggc cttgcagcag
    40561 cggctggatt cgctgatgct gcgcgacaga ctgcgttttt ctcggcgtct gcacggtgtt
    40621 aagaaggtta aaaatcctga tgcacaacag gccattttcc aggagatggc gaaagagatt
    40681 gaccaggcgg cagggaaagt cctgctgcgt gaagcggcac gaccggaaat tacttatcct
    40741 gacaatttac cggttagtca gaaaaaacag gacattctcg aagcgattcg tgatcaccag
    40801 gtggtgatcg tcgccgggga aacgggttct ggtaaaacga ctcagttacc gaaaatctgt
    40861 atggagctgg ggcgcgggat taaagggctg atcggccata cccagccgcg tcgcctggcg
    40921 gcaagaacgg tggcgaaccg tattgcggaa gagctgaaaa cggagccggg cggttgcatc
    40981 ggttacaaag tgcgtttcag cgatcacgtt agtgataaca cgatggtcaa gctgatgacc
    41041 gacggtatcc tgctggcgga gatccagcaa gaccgcctgc tgatgcagta cgacaccatc
    41101 attattgacg aagcacacga acgcagcctg aatatcgatt ttctgctcgg ctatttgaaa
    41161 gagttgctgc cgcggcgtcc tgacctaaaa atcattatca cttccgcgac tatcgacccg
    41221 gaacgctttt cgcgccactt taataatgcg ccgattatcg aagtctccgg tcggacctat
    41281 ccggtggaag tgcgctatcg accgattgtt gaagaagccg acgacaccga gcgcgatcag
    41341 ttgcaggcga tttttgacgc cgtagacgaa ctgagtcagg aaagccctgg cgacattctg
    41401 atctttatga gtggtgagcg ggaaattcgc gataccgccg atgcgctgaa caagctaaat
    41461 ctgcgtcata ccgaaatctt gccgctttat gcgcggcttt cgaacagcga acagaaccgc
    41521 gtgttccagt cgcacagcgg acggcgcatt gtgctggcga ccaacgtcgc ggaaacctcg
    41581 ctgaccgtac cggggattaa atacgttatc gaccccggta cagcacgtat cagccgctac
    41641 agctatcgca ccaaagtgca gcgtttgccg attgaaccca tttcgcaggc gtctgccaat
    41701 cagcgtaaag gccgctgtgg gcgtgtgtcc gaagggatct gtattcgtct ctattccgaa
    41761 gacgatttcc tttcgcgccc ggagtttacc gatccggaga ttctgcgtac caacctggcc
    41821 tcggttattt tgcagatgac cgcgctgggg ctgggcgata tcgctgcgtt cccgtttgtc
    41881 gaagcaccgg ataaacgcaa tatccaggat ggcgtgcgtc tgctcgaaga actgggcgcg
    41941 atcaccacgg atgaacaggc cagcgcctat aaactgacgc cgctcggtcg ccagctctcg
    42001 cagttgcctg tcgatccacg tctggcgcgt atggtgctgg aagcgcaaaa acatggctgc
    42061 gtgcgtgagg cgatgattat cacgtccgcg ctttccattc aggatccgcg cgagcgtccg
    42121 atggataaac agcaggcatc ggacgaaaaa catcgtcgct tccacgacaa agagtctgac
    42181 ttcctcgcgt ttgtgaatct gtggaattat cttggcgagc agcaaaaggc gctttcttcc
    42241 aacgccttcc gtcgcctgtg tcgtaccgat tatctcaact atctgcgcgt gcgcgaatgg
    42301 caggatatct acacccagtt gcgccaggtg gtgaaagaac ttggcattcc ggttaacagc
    42361 gaaccggcgg agtatcgcga aattcacatt gcgttgctga cgggtttact ttcccatatc
    42421 ggcatgaaag atgccgataa acaagaatat accggcgcac gtaacgcgcg tttctccatc
    42481 tttcccggtt ctggtttatt caaaaaaccg ccgaaatggg taatggtggc ggaactggta
    42541 gaaaccagcc gcctgtgggg gcgcattgct gcgcgtatcg acccggaatg ggtggagcct
    42601 gtcgctcagc atttgattaa acgcacctac agcgaacctc actgggaacg ggcgcagggc
    42661 gcggtgatgg caacggaaaa agtcactgtt tatggtttgc cgattgttgc cgcgcgcaag
    42721 gtcaactaca gccagatcga tccggcgtta tgccgtgaac tctttattcg ccatgcgctg
    42781 gtggaaggtg actggcagac gcgtcacgca ttcttccgtg aaaacctgaa actgcgggcc
    42841 gaagtggaag agctggaaca caaatcacgt cgccgcgata ttctggttga tgacgaaacg
    42901 ttgtttgagt tctatgacca gcgcatcagc cacgatgtga tctctgcacg ccacttcgac
    42961 agctggtgga aaaaagtcag ccgcgaaacc cctgatttgc tcaactttga aaaaagcatg
    43021 ttgatcaaag agggcgcaga aaaaatcagc aagctggatt acccgaactt ctggcatcag
    43081 ggcaatctca agctgcgttt gagctatcag tttgagcccg gcgcggatgc tgacggtgtg
    43141 accgtacata ttccgctgcc gttacttaac caggttgagg aaagcgggtt tgaatggcag
    43201 atccccggtc tgcgccgcga actggtgatt gctctgatta aatcgttgcc gaaaccggta
    43261 cgccgtaatt ttgtacccgc accaaactac gccgaagcgt ttttaggccg cgtcacaccg
    43321 ctggagttac cgttgctcga cagccttgag cgcgagttac ggcggatgac cggtgttacc
    43381 gttgaccgcg aagactggca ctgggatcag gtgcccgatc acctgaaaat caccttccgc
    43441 gtggtggacg acaaaaataa gaagctaaaa gaagggcgct cattacagga tctgaaagat
    43501 gcgctgaaag gcaaagtgca ggaaacgctg tccgcggtgg cggatgacgg tatcgagcag
    43561 agcgggctgc atatctggag ctttgggcaa ctgccggaaa gctacgaaca gaagcgcggc
    43621 aactataaag tgaaggcgtg gccggcgctg gtggatgaac gtgacagtgt ggcgatcaaa
    43681 ctgtttgata acccgctgga gcaaaaacag gcaatgtgga acggtcttcg ccgtctactg
    43741 ctgctaaata ttccctcgcc gatcaagtat ttacatgaga agttaccaaa caaagccaag
    43801 cttggactgt actttaaccc gtatggcaaa gtgctggagc tgatcgacga ctgtatctcc
    43861 tgcggtgtgg atcaactgat cgacgccaat ggtggcccgg tctggacgga agaaggcttt
    43921 gctgcgctgc atgagaaagt gcgtgccgaa ctgaacgaca cggtggtaga tattgcgaag
    43981 caggtcgagc aaattcttac ggcagtgttc aatatcaaca aacgtctgaa agggcgggtg
    44041 gatatgacca tggcactggg gctttctgac attaaagcgc agatgggcgg gttggtatat
    44101 cgcggttttg tcactggtaa cggcttcaaa cggctgggcg acacgctgcg atatttgcag
    44161 gcgattgaaa aacggctgga aaaactggcg gttgatccac atcgcgaccg tgctcagatg
    44221 ctgaaagttg aaaacgtcca gcaggcgtgg cagcaatgga tcaacaaact gccgcctgca
    44281 cgtcgtgagg atgaagacgt gaaagagatc cgttggatga tagaagagtt gcgcgttagt
    44341 tacttcgctc aacaacttgg tacgccttat ccgatttcag ataagcgtat tttgcaggcg
    44401 atggagcaga ttagcggtta accctgctat ttgcctgata aagaaaaaac ccggtaagca
    44461 tttagcgccg ggttttttat taattctaaa acggtaaggg taaaaattca ggaattcaga
    44521 aaaatacaat tctctgctgc aagatgaata atgtttatct acagcatttc cttaaaagat
    44581 atgtcaggct tgcggagtgg cggttaagga catacgactt cctcctttca gagtgctccg
    44641 cttctcacta ttatctcaca cagtattctt aagggaacga taaggaggaa ccatgaacat
    44701 taccccgttt ccgacgcttt cgccggcaac tatagatgcc ataaatgtta tcggacagtg
    44761 gctggcgcag gatgatttct ccggtgaggt gccgtatcag gccgattgcg tgatccttgc
    44821 aggcaatgcg gttatgccga ctatcgacgc ggcatgtaag attgctcgcg atcagcaaat
    44881 tcctttactg attagtggtg gtatcggtca ctcgacaact tttttgtata gcgccatcgc
    44941 acagcatccg cactacaaca ctatccgcac cactggcaga gcagaagcga ccatcctggc
    45001 ggatatcgct catcagttct ggcacattcc gcatgaaaaa atctggattg aagaccagtc
    45061 aacaaactgc ggtgaaaacg cacgctttag catcgcgcta ttgaaacagg ccgtagaacg
    45121 agttcatacg gctatcgttg ttcaggaccc caccatgcag cggcgcacga tggcgacgtt
    45181 ccgccgtatg actggggaca atcccgatgc accacgctgg ttaagttatc ccggattcgt
    45241 tcctcagtta ggaaataacg cagacagtgt aatctttatt aatcagttac aaggattatg
    45301 gccggttgag cgttatctct cactactcac tggcgagctg ccgcgtttac gcgatgatag
    45361 cgatggctac ggtccccgcg ggcgagattt tatcgttcac gttgattttc cggcagaagt
    45421 catccatgca tggcaaacgc tgaaacatga tgcggtgctc atcgaggcga tggaaagtcg
    45481 ctcgttacgt taaaaattgc ccgtttgtga accacttgtt tgcaaacggg catgactcct
    45541 gacttttatt tctgcctttt attcctttta cacttgtttt tatgaagccc ttcacagaat
    45601 tgtcctttca cgatgccgtc tctctgatga ttgatgttaa ttaacaatgc attcaccgaa
    45661 aataaacata taaatcacag gagtcgccca tgtcagtacc cgttcaacat cctatgtata
    45721 tcgatggaca gtttgttacc tggcgtggag acgcatggat tgatgtggta aaccctgcta
    45781 cagaggctgt catttcccgc atacccgatg gtcaggccga ggatgcccgt aaggcaatcg
    45841 atgcagcaga acgtgcacaa ccagaatggg aagcgttgcc tgctattgaa cgcgccagtt
    45901 ggttgcgcaa aatctccgcc gggatccgcg aacgcgccag tgaaatcagt gcgctgattg
    45961 ttgaagaagg gggcaagatc cagcagctgg ctgaagtcga agtggctttt actgccgact
    46021 atatcgatta catggcggag tgggcacggc gttacgaggg cgagattatt caaagcgatc
    46081 gtccaggaga aaatattctt ttgtttaaac gtgcgcttgg tgtgactacc ggcattctgc
    46141 cgtggaactt cccgttcttc ctcattgccc gcaaaatggc tcccgctctt ttgaccggta
    46201 ataccatcgt cattaaacct agtgaattta cgccaaacaa tgcgattgca ttcgccaaaa
    46261 tcgtcgatga aataggcctt ccgcgcggcg tgtttaacct tgtactgggg cgtggtgaaa
    46321 ccgttgggca agaactggcg ggtaacccaa aggtcgcaat ggtcagtatg acaggcagcg
    46381 tctctgcagg tgagaagatc atggcgactg cggcgaaaaa catcaccaaa gtgtgtctgg
    46441 aattgggggg taaagcacca gctatcgtaa tggacgatgc cgatcttgaa ctggcagtca
    46501 aagccatcgt tgattcacgc gtcattaata gtgggcaagt gtgtaactgt gcagaacgtg
    46561 tttatgtaca gaaaggcatt tatgatcagt tcgtcaatcg gctgggtgaa gcgatgcagg
    46621 cggttcaatt tggtaacccc gctgaacgca acgacattgc gatggggccg ttgattaacg
    46681 ccgcggcgct ggaaagggtt gagcaaaaag tggcgcgcgc agtagaagaa ggggcgagag
    46741 tggcgttggg tggcaaagcg gtagagggga aaggatatta ttatccgccg acattgctgc
    46801 tggatgttcg ccaggaaatg tcgattatgc atgaggaaac ctttggcccg gttctgccgg
    46861 tggtcgcatt tgacacgctg gaagaggcta tctcaatggc taatgacagt gattacggcc
    46921 tgacctcatc aatctatacc caaaatctga acgtcgcgat gaaagccatt aaagggctga
    46981 agtttggtga aacttacatc aaccgtgaaa acttcgaagc tatgcaaggc ttccacgccg
    47041 gatggcgtaa atccggtatt ggcggcgcag atggtaaaca tggcctgcat gaatatctgc
    47101 agacccaggt ggtttattta cagtcgtaat gagtaaaaga ggcggaggtt ttttcctccg
    47161 cctgtgcgcg tcagagttta gcgaattttt cgagggtgcg aataagctgc gtgacgaagc
    47221 catattcgtt atcgtaccag gcgaccgttt tcaccagttg taaatcgccc acggcggtaa
    47281 tttccgtttg cgtggcatca aacaccgaac cgaaatggct gccaatgata tcggaagaga
    47341 ctatttcttc atcggtataa ccaaatgact cgttattggt ggttgcttgt ttaagtgcgt
    47401 tattcacctc ttcggcagtc actttttttc cgagaatcga taccagttca gtgaccgaac
    47461 ctgttttcac cggcacgcgt tgcgcatgac ctttcagttt gccgctcagt tccgggatca
    47521 ccagaccaat ggcttttgcc gcccccgtag tgtggggaat gatattttct gccgctgcgc
    47581 gtgaagcacg taaatcttta ccacgtgggc catccaccag tgactgggtg ccagtatagg
    47641 catgaatggt cgtcatcgtg ccgacttcta tcccgaaact gtcatgcaag gctttggcca
    47701 tcggcgcaag acagttagtg gtgcatgacg ccacggaaac aatggtgtcg ttgccatcca
    47761 gagtgtcgtc attgacgtta taaacgatag ttttcatttc accggcaggg gcggaaatca
    47821 acaccttctt cgcaccagca tcaagatgcg cctgcgattt ctcggcggag gtataaaagc
    47881 cagtacattc gacaatgatt tctgcccctt tcgctttcca cggaatattt ttagcctctt
    47941 tttcggcgta aaccgcgata cttttcccat caacgataag tgaatcttcc gtaaaatcaa
    48001 cgctccaggg gaacggacca tagtttgaat catgtttcag cagataggcg agaatttttg
    48061 gggaagtgag atcattaata gcgacaacgt ctatgttgct tttgacttca agtaatcgac
    48121 gcaacaccag tcgaccgata cgaccaaaac cgttaatacc aactttactc atggttttct
    48181 cctgtcagga acgttcggat gaaaattgat cctttccagg cttagcccag gattgtggga
    48241 tgggcaatct ccattcttac agtgaaacgt aacgtactga aaacgggtga acaatattta
    48301 atgaaatttt gagaaaagcc cgttatgtta acggaaaatt atgttaaagc aggaaatgtt
    48361 atggaaaata aatactcaag gttacaaatc agcattcact ggctggtctt tttgctggtt
    48421 atcgcagcgt attgcgcaat ggagtttcgt ggtttcttcc cacgtagcga tcggccactc
    48481 atcaacatgg ttcatgtttc ctgtggtatc tcaattctcg tgctgatggt ggttcgtctt
    48541 ttgttaagac tgaaataccc aaccccgccg attataccta agccaaaacc gatgatgacg
    48601 ggactggcgc atttgggaca tttggtgatt tatctcctgt ttattgcgct gccagtgatt
    48661 ggtttggtga tgatgtataa ccggggcaac ccgtggtttg cgtttggttt gacgatgcct
    48721 tacgcttcag aggccaattt cgaacgggtt gatagcttaa agtcgtggca tgagacgctg
    48781 gcgaatctgg gatattttgt catcgggttg cacgctgcgg ctgcactggc acaccactat
    48841 ttctggaagg acaacacact tctacgcatg atgccgcgta aacgttcctg aaggatattt
    48901 aaagaaaacg cctgtactaa aaccgacccg tggtacaggc gaagaatacg ggtctacatc
    48961 ggaagcgcct attatattta tttgtatgac aaataaaacc ataatccttg cccatacgtc
    49021 catctggctt atttttaatc aattcacccg atctttgatc tcatcaacgg tatcaaaata
    49081 aaccagcgta taacgttcaa atcgaacata agattcgata aaccatggag gttatatgaa
    49141 aaaactggca cttattttgt ttatgggaac gcttgtttcc ttttatgccg atgccgggcg
    49201 caaaccctgt tctggttcga aaggggggat ctcacactgt acggcaggcg gcaaatttgt
    49261 ctgtaatgat ggttctatta gtgcctcgaa aaaaacatgc actaactgaa gtgtaaaagg
    49321 ggtgccatga gaaaatgaat ctgctagtca gatgcgcggg gaaaatcccc gcgcttgccc
    49381 ttacctggac gtgcaggcca tgagcgcagc aacctcctta tcaccgtccc ggaaccgcag
    49441 ttcgtagagc gtttgtcggg tcaggagtgt gaatgtcaga atcgtaatgc agataatgag
    49501 cagacacacc accagagggt tgtgcttcat agcctttctc cttgccggat ggcgggtaag
    49561 aggctaagat ctgaattgct aggttcattc gttggcctcg gttgatagaa atatcggtcg
    49621 gggccttcgt ctttctgatt cccggttagc ctgaaaacag aaagtctcag gcacccgcag
    49681 gcatcctatg aggtttcctt agggacgaaa ataatcactt cacgaaattg cgtgctgttt
    49741 tccagaattt ttcgtcattc gggttagcca gtttagccat tcgttactct ctttattcca
    49801 atagcattaa ttttctctgc aataattgtt gtaaaaatgt gacgcaaaga ggtttttggt
    49861 cataagtaat taccgtcaag tgccgatgac tttctatcag gagtaaacct ggacgagaga
    49921 caacggtaat gaatacaact ccctcacatc gattaggttt tttgcatcac atcaggctgg
    49981 ttccgttatt tgcctgcatt cttggcggta tcttagttct attcgcatta agttctgctc
    50041 tggctggcta tttcctctgg caggccgatc gcgatcagcg tgatgttact gcggagattg
    50101 agattcggac cgggttagcg aacagttcag attttttgcg ttcagcccgg atcaatatga
    50161 ttcaggccgg ggctgcgagt cgtattgcgg aaatggaagc aatgaagcgc aatattgcgc
    50221 aagccgaatc ggagattaaa cagtcgcagc aaggttatcg tgcttatcag aatcgaccgg
    50281 tgaaaacacc tgctgatgaa gccctcgaca ctgaattaaa tcaacgcttt caggcttata
    50341 tcacgggtat gcaacctatg ttgaaatatg ccaaaaatgg catgtttgaa gcgattatta
    50401 atcatgaaag tgagcagatc cgaccgctgg ataatgctta taccgatatt ttgaacaaag
    50461 ccgttaagat acgtagcacc agggccaacc aactggcgga actggcccat cagcgcaccc
    50521 gcctgggtgg gatgttcatg attggcgcgt ttgtgcttgc cctggtcatg acgctgataa
    50581 catttatggt gctacgtcgg atcgtcattc gtccactgca acatgccgca caacggattg
    50641 aaaaaatcgc tagtggcgat ctgacgatga aggatgaacc ggcgggtcgt aatgaaatcg
    50701 gtcgcttaaa tcgtcattta cagcaaatgc agcattcact ggggatgaca gtagggactg
    50761 ttcgacaggg tgcggaagag atttatcgtg gcaccagcga aatttcagct ggcaatgcgg
    50821 acctgtcatc tcgcaccgaa gaacaagcgg cggcaatcga acaaactgcc gccagcatgg
    50881 agcaactcac tgcgacggtg aaacagaatg cggataacgc gcatcatgcc agcaaactgg
    50941 cgcaagaggc ttctattaaa gccagcgatg gcgggcagac ggtttccggt gtagtaaaaa
    51001 cgatgggcgc tatctccacg agttcgaaga aaatttctga gatcaccgcc gtcatcaaca
    51061 gtattgcttt ccagacgaat attctggcac tgaatgctgc cgttgaagcc gcgcgagcgg
    51121 gtgagcaagg gcgtggattt gccgttgtcg ccagcgaagt acggacactc gcaagccgca
    51181 gcgctcaggc ggcgaaagag attgaaggct tgatcagtga atcagtcagg ttaattgacc
    51241 tggggtcgga tgaggtggca acggcaggga aaaccatgag cactattgtt gatgccgtcg
    51301 cgagtgtcac acatatcatg caggaaatcg ccgccgcctc ggatgaacaa agtagaggca
    51361 taactcaggt tagccaggcg atttctgaaa tggataaggt gacgcaacag aatgcttctc
    51421 tggtagaaga ggcctcagca gcggcggtgt cccttgaaga acaggctgca cgattaactg
    51481 aggcggtgga tgtattccgt ctgcacaaac attctgtgtc ggcagaacct cgcggagcgg
    51541 gtgaaccagt tagtttcgct acggtgtgaa aatgttcaag gagggatcga cagatccctt
    51601 cacctttcag aacggcattg attttcgaat agcgttaatc atcaactggc aaccagaaga
    51661 gaacgtcgca tctacgcggg tcagtattcc aatcggttcg cctgcaccat gtcccggaac
    51721 aggcagggcc accagcgtgg catgacgcag gtcgtctttt acagcgccag aagggacaaa
    51781 ccacacgtaa tcgtattcaa ccgtaagttg acgagatagc gaagcagaca gcgtttcgat
    51841 acaacccgaa ggaattttac agccctggct ctgcactaat gcatctgaat gctggcgtgg
    51901 cgcagtgcct tctggtgata caacgaccgg ccattccagc acccggctta gcgttacgtt
    51961 ctcctgaagt agcgggtgat tagggcggac aaccagcttc aacgattcaa gaaacagcag
    52021 ttcgtaatta agcccggtca tcagttcagg atctgacatc cgaccaatgc cgatatcgat
    52081 ttccccggtt tttaaacccg ccagaatcat agggttactc attgtcgcaa cttgcaaggt
    52141 cgtctctttt tgttgctgat gaaactgacc tataaccgaa ggtaatatcc ccagtgccgc
    52201 agtaggtagt gcaccaaccc tgacgacatc attattaaga ccttctttac gatgaagcga
    52261 ctgtccggca gtgttgatgg cgtcaagaac tctgactgca tgcgttaaaa attgttcgcc
    52321 gggtaaggta agttgcgccc cctgacgacc acgctcaaac aagcgagcgc cagtcagctg
    52381 ctccagttca ttcaatgtct tagagagcgc aggttgactc aaattaaggg tttcagccgc
    52441 gcgccccaaa gttccttgtt gtgcgacagc tacgaatgta tgaaggtggc gcaaacggat
    52501 gcgctgacta aacagactat ttttttccat aagcgatgtt aaaaacgaag cggtgtcgct
    52561 gacaagtgaa gttgtttgat tatgataact tgattgcaaa atattattaa caattaaagc
    52621 aattatgtta cagcaaaatg gataatattg atgttttcgc ggcgagatca cagtttgtaa
    52681 attcttcccg caagagtgaa tgcggttacc tacactccag attactgacc actggaggca
    52741 gacactatgg cgaacagcat cacggcggat gagattcggg aacagttttc gcaggcaatg
    52801 tcagccatgt accagcaaga agttccgcaa tatggcacgc tgctggaact ggtagctgat
    52861 gtgaatctgg ctgtgctgga aaacaatcct caactgcacg aaaaaatggt aaatgcagac
    52921 gagctggcgc gactgaatgt tgaacgtcat ggggcgattc gcgttgggac tgcacaagag
    52981 cttgctactc ttcggcggat gtttgccatt atggggatgt acccggtgag ctattacgat
    53041 ctctcgcagg caggggtgcc ggtacattcg acagcatttc ggcccattga tgatgcttct
    53101 ctggcgcgta atcccttccg cgtttttacc tccttactcc gccttgagct tatcgagaac
    53161 gaaattttgc gccagaaagc ggcggagatt ctgcgtcagc gcgatatctt caccccacgt
    53221 tgtcgacaac tgttagagga atatgagcag cagggcggtt ttaacgaaac acaggcacag
    53281 gagtttgtgc aggaagccct ggaaacgttt cgctggcacc agtcagcaac ggtagatgaa
    53341 gaaacctatc gcgccttgca caacgaacat cggttgattg ctgatgtggt ctgttttcct
    53401 ggatgccata tcaaccacct gacaccacgt acgctggata ttgaccgggt gcagtcgatg
    53461 atgcctgaat gcggaattga acccaaaatt ctcatcgagg ggccgccgcg ccgcgaggta
    53521 ccgattttac tacgccagac cagctttaaa gcactggaag agacggtgtt gtttgcgggg
    53581 cagaaacagg gcacgcatac cgcgcgcttt ggtgaaattg agcagcgtgg cgtggcatta
    53641 acgccgaaag ggcgacaact gtatgatgat cttctgcgta acgctggaac cgggcaggat
    53701 aatctcactc accaaatgca tttacaggaa accttccgca cttttcctga cagtgagttt
    53761 ttaatgcgtc agcaagggct ggcatggttc cggtaccgtc tgacgccttc aggtgaggcg
    53821 catcgtcagg cgattcatcc cggagacgat ccacagccct taattgaacg tggttgggtc
    53881 gcggcgcaac ccattaccta tgaagatttc ttgcccgtta gcgcggcggg gatcttccag
    53941 tcaaatctgg gtaatgaaac gcagacacgc agtcacggta atgccagtcg cgaagcattt
    54001 gagcaggcgt tgggttgtcc ggttttggat gagttccagc tttaccagga agcggaagaa
    54061 cgcagtaaac gtcgctgtgg tttgctttaa attctgacca tccgcctttg caaaaatttg
    54121 cctgatttta caaacgaatc aggctcatcc catcgacata aaaaaaatgc cgatttatgc
    54181 atattctctc agttcaacaa ttggattatt aataaatatt gtctagagtg agcggtcata
    54241 aataagcact ttcttgccgc tgaaaacgac cagcgcggga ccattcacaa caccagaagg
    54301 actcactttc aggtatggat cgtagacgat ttattaaagg ttcaatggct atggccgccg
    54361 tgtgcggtac cagcggcatt gcttctcttt tttctcaggc ggcattcgcg gcagattctg
    54421 atattgccga cgggcaaacc cagcgttttg acttctccat tctacagtca atggcgcacg
    54481 acttagcgca aacagcgtgg cgtggtgcgc ctcgtccgtt acctgacacg ctggcgacaa
    54541 tgacgccgca ggcttataac agtattcaat acgacgccga aaaatcgctc tggcataacg
    54601 ttgagaaccg tcaactggac gctcagttct tccatatggg aatgggattc cgtcgccgcg
    54661 ttcgtatgtt ttctgtagat ccagcaacac atctggcgcg tgaaattcac tttcgcccgg
    54721 agttgttcaa atacaacgat gcgggtgttg atacaaaaca attagaaggg caaagcgatc
    54781 tcggctttgc cggttttcgc gtgtttaaag cccccgaact ggcgcgccgt gatgtagtat
    54841 catttctcgg cgcgagttat ttccgcgccg ttgatgatac atatcaatac ggtttgtcgg
    54901 cccgcggcct ggcgatcgac acttacactg acagtaaaga agagttcccc gactttaccg
    54961 ccttctggtt tgatacggta aaaccggggg caactacctt taccgtttat gcgttgctcg
    55021 atagcgccag cattactggt gcctataagt tcactatcca ttgtgagaaa agtcaggtga
    55081 ttatggatgt ggaaaatcac ctgtatgcgc gcaaagacat taaacagctg ggcattgcgc
    55141 cgatgaccag tatgttcagc tgcggtacta atgaacgtcg gatgtgcgat acaattcatc
    55201 cgcaaattca tgactctgat cgtctgtcca tgtggcgggg caacggcgag tggatttgcc
    55261 gtccgctgaa taatccgcaa aaattgcagt tcaatgctta caccgacaac aacccgaaag
    55321 ggtttggttt attgcaactg gatcgtgact tctcccatta tcaggacatt atgggctggt
    55381 ataacaaacg cccaagtctg tgggtggagc cgcgtaacaa gtggggtaag ggcaccatcg
    55441 gcctgatgga aatcccaaca acgggcgaaa cgctggataa cattgtctgc ttctggcagc
    55501 cagaaaaagc tgtaaaagca ggtgatgagt ttgcattcca gtatcgtctg tactggagtg
    55561 cgcaaccgcc tgttcattgc ccattagcgc gcgttatggc gacgcgtacc ggcatgggcg
    55621 gtttcccgga aggttgggca ccaggtgaac actatcccga aaaatgggcg cgtcgttttg
    55681 ccgtcgattt cgttggtggt gatctgaaag ctgccgcacc aaaaggcatt gagccggtga
    55741 ttacgctttc cagtggggaa gcgaagcaaa tcgaaattct ctatattgaa cccattgatg
    55801 gttatcgtat tcagtttgac tggtatccga cttcggactc cactgatccg gtcgatatgc
    55861 ggatgtatct gcgttgtcag ggcgacgcta tcagtgaaac atggctgtat cagtatttcc
    55921 cgccagcgcc ggataaacgt cagtatgttg acgaccgcgt gatgagttaa tcgttttttc
    55981 ttcggcacct tcttcgggag gtgccgtctg gttaaacacg atcccgctcg catttttccc
    56041 taagttaaat gagtaatctg atggtgtgta tttcagatac accttgtcag ccactaacag
    56101 ggagtgcgta tgtttccaga ataccgagat ttaatatccc gtctgaaaaa cgaaaatcct
    56161 cgctttatgt ccttgttcga taaacacaat aaacttgatc atgaaattgc cagaaaggaa
    56221 ggttccgacg gtcgagggta caatgcggaa gtggtccgca tgaaaaaaca aaagctacag
    56281 ttaaaagatg agatgctcaa aatcctgcag caggagagcg tcaaagaggt gtaaactttc
    56341 ctaagccgcc agccaggcgg cttttttaac aacagcatgg attgactgga gataagatga
    56401 ctgaaacgat aaaagtaagc gaatcacttg aattacatgc tgttgcggaa agtcacgtca
    56461 cacctcttta tcagttaatc tgtaaaaata aaacctggtt acagcagtcg ctaaactggc
    56521 cgcagttcgt tcagagtgaa gaggacacgc gaaaaacggt gcagggtaat gtgatgttgc
    56581 atcaacgcgg ctatgccaaa atgttcatga ttttcaaaga agatgaactt atcggcgtta
    56641 tctcgtttaa tcgtattgaa ccactgaata aaactgctga aatcggctac tggctggacg
    56701 aatctcatca ggggcagggg atcatttctc aggcgctgca ggcattgatt catcattacg
    56761 ctcagtctgg tgaacttaga cgcttcgtga tcaaatgtcg ggtggacaat ccgcaaagca
    56821 accaggtcgc tttgcgcaat ggttttatcc ttgaaggttg cctgaaacag gctgagttcc
    56881 tgaatgatgc ctatgatgat gtgaacttat acgcgcgtat tatcgattca taataaccct
    56941 gccagcggcg ttcgcgtaat gcgctcctcg ccgttaatga cttttggacc acggacatga
    57001 accgtgtcgc catcaaaggc ttcaacgacg gcgtggtcgg ttaactccac atggttttca
    57061 attatcaccg cacctgaaat acggctctca ccttgtatta caacgtgctc gtcgagcaga
    57121 atcggtccac cacgtaccac ggcatttccg ccaatcaaga catgatgttt taacacacaa
    57181 ttaccttcca caatggcata ttccgccacc tgcgaactgt aatgaatcgt cggaatggca
    57241 tcttcttcta tgccagcttt cacctgcgcg tgaccgtaga ctttagcgca atcgcatagc
    57301 cagacgttgt tctcttcatt accttcaaca ctggcaaaat caaaaacttc ggcgcgatgt
    57361 tcaataaaag cataccggac gacggcatcg ccataaattt gtgcctggtg gacaatacgc
    57421 gaggcgctaa cccttgcgcg atcataaatt tggagcagga gttgatggtc gggcgttaag
    57481 ccttgtgcgg cgacgatcat agaatgttga tcaattaagg cgtgaccaaa tattctacat
    57541 tgcccgtaaa ctaatgagtc atgaatggtg acactgtcac ttatgtatgc accctggctg
    57601 atttcactat tatcgatcca gacattatcc gttgcgtaaa cctctcccca cagtacgctg
    57661 gtgccggtga tgcgcgtatt accggaaatc accgttccgc cgaacgcaat agcattctgg
    57721 tcgtaaatcc agcaatttcc ttcctgtgct aacaccgttt cgcgatcgat ccagccgcca
    57781 gcggttcctg ctatcacatc gttaaaatcg ctaatggcga taatctgccg taataacaca
    57841 ttttttttag tgccatcttc ctgataacta aaggctcgct gttcttcact tagacgatat
    57901 ttgcgcatag cgttttccca caggtgactt actataaccg tagcaaattc tgcggctctg
    57961 gctatgctcg agaaaattcc ataaaatgca tttcaaatat actttataaa ttaaacaaaa
    58021 tgagtaagaa gatgcagagc gataaagtgc tcaattttcc ggcaggctac tttggtattg
    58081 tgttggggac gatagggatg ggatttgcct ggcgctatgc cagccaggtt tggcaggtca
    58141 gccactggtt aggggatggg ctggtgattc tggcgatgat catctgggga ttattaacta
    58201 gcgcatttat tacccgactc atacgctttc cgcatagcgt gctggcggaa gttcgccatc
    58261 cagtgctgag cagttttgtg agtttgtttc cggcaacgac gatgctggtg gcgattggtt
    58321 ttgttccgtg gtttcgccca ctggcggtgt gcctgttcag ttttggtgtc gtggttcagt
    58381 tggcttatgc cgcctggcaa actgcgggat tatggcgcgg atctcaccct gaagaagcta
    58441 ccacgcctgg actgtatctg ccgacagttg ccaacaactt tatcagcgca atggcctgtg
    58501 gtgcgttggg ctacaccgac gccggtctgg tgtttttagg cgcaggcgtt ttctcatggc
    58561 taagccttga accggtgatc ttgcagcgtc tgcgcagttc gggagaatta cccacggcac
    58621 tgcggacatc actcggcatt cagctcgctc ctgcgctggt ggcttgtagt gcctggctga
    58681 gcgtcaacgg cggcgagggt gacacgctgg cgaaaatgct tttcggttat ggactgctgc
    58741 aactgctgtt tatgctacgt ctgatgccat ggtatctctc ccagccattt aatgcttcat
    58801 tctggagttt ctcgttcggc gtatctgcac tggcaaccac cggtttgcat ctggggagtg
    58861 gcagcgataa tggatttttc catacgctgg cggtgccgct gtttatcttt accaatttta
    58921 ttattgcaat actgctcatc cgtacttttg cgcttctgat gcagggaaaa ttgttagtca
    58981 gaaccgagcg cgccgtttta atgaaagcag aggacaaaga atgatcattc gtgacgaaaa
    59041 ctattttact gataaatatg aattaacccg cacacactct gaagtactgg aagcggtgaa
    59101 agtggttaaa ccgggtaaaa cgctggatct gggctgtggc aatggtcgta acagtcttta
    59161 cctggcagcc aatggttatg atgttgacgc atgggataaa aatgccatga gtatcgccaa
    59221 cgtcgagcgc attaaatcca ttgaaaatct ggataattta cacacccgag tcgttgatct
    59281 gaataacctc acatttgata gacagtacga ttttattctt tcgactgtgg tactgatgtt
    59341 ccttgaggct aaaaccatcc cagggctgat tgtcaatatg caacgttgca ctaaacctgg
    59401 tggttacaac ctgattgtgg cggcgatgga taccgctgat tatccatgta ccgtcggctt
    59461 cccgtttgcc ttcaaagagg gagaattacg tcgatattac gaaggctggg agagggtgaa
    59521 atacaatgaa gacgtcggcg aactgcaccg caccgacgcc aacggtaatc gtattaaact
    59581 gcgtttcgcc acgatgctgg cacgtaaaaa atgacccgct aagaataagg cgcgtgaaaa
    59641 ttccccacgc tgagatgatt tactgttctt cttttcggta agcatatttt ttatcgaagg
    59701 gatgtgaaat taatcacagt agtcgaagtt ttttagcagc ttaacttact gaaatttaac
    59761 tactgatgat tgacttagcc cctttttcgg cattgactat gtcgtctgaa aaggggctga
    59821 aaaatttatt ttcaccaaca ctttttttgc cacaacacga agcggcgctt tttgctataa
    59881 cttagaaagt aatataatca tctcaggaaa ctattcatgc gtaccacatc atttgcgaaa
    59941 gttgcagctt tatgcggctt gttggctctg tctggttgtg cctctaaaat cacccagcca
    60001 gataaatatt ctggtttttt aaacaattac tctgatttaa aagaaacaac ctcagcaaca
    60061 ggtaaacctg ttttacgttg ggtagacccg agttttgatc aaagcaaata tgacagcatc
    60121 gtctggaacc caatcactta ttatccggta ccaaaacctt ctacccaggt agggcagaaa
    60181 gttctggata aaattttgaa ctataccaac accgaaatga aagaagcgat agcgcagcgt
    60241 aaaccactgg ttaccaccgc tgggccgcgt agtctgattt tccgtggggc cattaccggt
    60301 gtagatacca gcaaagaagg gctgcaattc tatgaagtgg ttcctgttgc attagtggtt
    60361 gcggggacac aaatggctac aggccaccgt accatggata ctcgcctcta ttttgaaggt
    60421 gagctgattg atgcagcgac taataaaccg gttatcaaag tcgttcgtca gggcgaaggt
    60481 aaagacctga ataacgaaag tacgccaatg gctttcgaaa atattaaaca agttattgat
    60541 gacatggcga ccgatgccac catgtttgac gttaacaaaa agtagttcca gacgcgccat
    60601 cgttagatgg cgctttttat ccggtgcgcc gtaaaacccc atccttcagg gcggggatat
    60661 aaggcgcggt tttccacctg accaggtgtt tgctgttgtt caatgtattg gcggatgacg
    60721 gatattggcg cacctccgca gctactggca aaatagccag gactccacaa aacgcctttg
    60781 tagtaatacc tgactgcaat atctggtcga tctcgtcgca gtaacctact cgatacgcct
    60841 ttgaggctgt ttaccagact ggatatcgcc agtttgggag gatagttaat taacaaatgg
    60901 acgtgatctg gttcgccatc catttaaacc agttcagctt caaaatcagc acatacattt
    60961 gaaaagtaag tgcgtagttt ttctgtcgcg tcatagtcaa aaatctgacg tcggtatctg
    61021 gtgacaaaga ccaggtgaac atgcatcagg aaaacacaat gcttccccgt cggatatcgg
    61081 tttctttatt catagaccaa agtatcattt ggcctgtgaa acgattacag gcatttaaat
    61141 tccagttaag acccggtggt caacaggagc gtgaaatgag gcgcttcgca ggcgcatgtc
    61201 gtttcgtttt caatcgtgct ctggcgcttc agaatgagaa tcatgaggcc ggtaataaat
    61261 acatccctta cgggaaaatg gcttcctggc tggttgagtg gaaaaacgcc actgaaacgc
    61321 aatggcttaa agattcgccc tcacagccat tgcaacagtc actgaaaggc
//
LOCUS       DAZUDJ010000023        59139 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.023, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000023 DAZUDJ010000000
VERSION     DAZUDJ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 59139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59139
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.023"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            188..859
                     /locus_tag="ACHY1N_001979"
     CDS             188..859
                     /locus_tag="ACHY1N_001979"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L deacetylase family protein"
                     /protein_id="HFS4044299.1"
                     /translation="MDKVLDSALLSSANKRKGILAIGAHPDDIELGCGASLARLAQKG
                     IYIAAVVMTTGNSGTDGIIDRHEESRNALKILGCHQTIHLNFADTRAHLQLNDMISAL
                     EDIIKNQIPSDVEIMRVYTMHDADRHQDHLAVYQASMVACRTIPQILGYETPSTWLSF
                     MPQVFESVKEEYFTVKLAALKKHKSQERRDYMRHDRLRAVAQFRGQQVNSDLGEGFVI
                     HKMIL"
     gene            869..2065
                     /gene="yaiP"
                     /locus_tag="ACHY1N_001980"
     CDS             869..2065
                     /gene="yaiP"
                     /locus_tag="ACHY1N_001980"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4044300.1"
                     /translation="MKTWIFICMSIAMLLWFLSTLRRKPSQKKGCIDAIIPAYNEGPC
                     LAQSLDNLLRNPYFCRVICVNDGSTDNTEAVMAEVKRKWGDRFVAVTQKNTGKGGALM
                     NGLNYATCDQVFLSDADTYVPPDQDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHI
                     RATVKLPMIVMKRTLQQLLGGAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTL
                     VANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIF
                     PMLLVVIYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWIGVVCVIGAFSAWFHRCWLL
                     VPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSQPSVTGT
                     EKLSEA"
     gene            2043..2624
                     /locus_tag="ACHY1N_001981"
     CDS             2043..2624
                     /locus_tag="ACHY1N_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001308433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFS4044301.1"
                     /translation="MKNYLKLNVKEKNIQIADQVIIDETAGEVVIGANTRICHGAVIQ
                     GPVVIGANCLIGNYAFIRPGTIISNGVKIGFATEIKNAVIEAEATIGPQCFIADSVVA
                     NQAYLGAQVRTSNHRLDEQPVSVRTPEGIIATGCDKLGCYIGQRSRLGVQVIILPGRI
                     ISPNTQLGPRVIVERNLPAGTYSLRQELIRTGD"
     gene            2626..3399
                     /gene="yaiO"
                     /locus_tag="ACHY1N_001982"
     CDS             2626..3399
                     /gene="yaiO"
                     /locus_tag="ACHY1N_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiO family outer membrane beta-barrel protein"
                     /protein_id="HFS4044302.1"
                     /translation="MIKRTLLAAAIFSALPAYAGLTSITAGYDFTDYSGDHGNRNLAY
                     AELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
                     VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGVSLYTGPVITSYRYTH
                     YDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSVSLQR
                     IQPLTEQLNLGLTAGKVWYDTPTDDYNGLQLAAHLTWKF"
     gene            3584..3859
                     /gene="frmR"
                     /locus_tag="ACHY1N_001983"
     CDS             3584..3859
                     /gene="frmR"
                     /locus_tag="ACHY1N_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414891.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formaldehyde-responsive transcriptional
                     repressor FrmR"
                     /protein_id="HFS4044303.1"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     gene            3894..5003
                     /gene="frmA"
                     /locus_tag="ACHY1N_001984"
     CDS             3894..5003
                     /gene="frmA"
                     /locus_tag="ACHY1N_001984"
                     /EC_number="1.1.1.284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="HFS4044304.1"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     gene            5096..5929
                     /gene="fghA"
                     /locus_tag="ACHY1N_001985"
     CDS             5096..5929
                     /gene="fghA"
                     /locus_tag="ACHY1N_001985"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018738 - S-formylglutathione hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0046294 - formaldehyde catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HFS4044305.1"
                     /translation="MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAANEKLP
                     VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHYKMYDYIRNELPDLVMQHFPATTRKSISGHSMGGLGALVLALRNPD
                     EYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKDAWLNYDPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     gene            complement(6054..6593)
                     /gene="yaiL"
                     /locus_tag="ACHY1N_001986"
     CDS             complement(6054..6593)
                     /gene="yaiL"
                     /locus_tag="ACHY1N_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414888.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HFS4044306.1"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
                     FVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDDPYADFKVPDDLMW"
     gene            complement(6695..7906)
                     /gene="mhpT"
                     /locus_tag="ACHY1N_001987"
     CDS             complement(6695..7906)
                     /gene="mhpT"
                     /locus_tag="ACHY1N_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-(3-hydroxy-phenyl)propionate transporter MhpT"
                     /protein_id="HFS4044307.1"
                     /translation="MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQA
                     FALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKSILIGSVALFGLFSLATAIAWD
                     FPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
                     AGANLAWQTVFWVGGVVPLILVPLLMRWLPESAVFAGEKQAAPPLRALFAPETATATL
                     LLWLCYFFTLLVVYMLINWLPLLLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDK
                     LRPVTMSLLIYSGMLASLLALGTVSSFNGMLLAGFVAGLFATGGQSVLYALAPLFYSS
                     QIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMS
                     RRSRMQPCADA"
     gene            complement(8181..9194)
                     /gene="mhpE"
                     /locus_tag="ACHY1N_001988"
     CDS             complement(8181..9194)
                     /gene="mhpE"
                     /locus_tag="ACHY1N_001988"
                     /EC_number="4.1.3.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HFS4044308.1"
                     /translation="MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSI
                     EVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQA
                     GARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
                     TCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCD
                     RIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVD
                     RETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLR
                     NNK"
     gene            complement(9191..10141)
                     /gene="mhpF"
                     /locus_tag="ACHY1N_001989"
     CDS             complement(9191..10141)
                     /gene="mhpF"
                     /locus_tag="ACHY1N_001989"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase"
                     /protein_id="HFS4044309.1"
                     /translation="MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGL
                     ARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDL
                     TPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
                     KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEAS
                     QDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEV
                     EGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA"
     gene            complement(10138..10947)
                     /gene="mhpD"
                     /locus_tag="ACHY1N_001990"
     CDS             complement(10138..10947)
                     /gene="mhpD"
                     /locus_tag="ACHY1N_001990"
                     /EC_number="4.2.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308432.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="HFS4044310.1"
                     /translation="MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHI
                     NVQYDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNEIIPFSRVLQA
                     RIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
                     CGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASL
                     GEPLRAGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS"
     gene            complement(10957..11823)
                     /gene="mhpC"
                     /locus_tag="ACHY1N_001991"
     CDS             complement(10957..11823)
                     /gene="mhpC"
                     /locus_tag="ACHY1N_001991"
                     /EC_number="3.7.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414883.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-6-oxonona-2,4-dienedioate hydrolase"
                     /protein_id="HFS4044311.1"
                     /translation="MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGS
                     GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQ
                     LDIAKIHLLGNSMGGHSSMAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
                     LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFP
                     DFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWTQWEHADA
                     FNQLVLNFLARP"
     gene            complement(11841..12785)
                     /gene="mhpB"
                     /locus_tag="ACHY1N_001992"
     CDS             complement(11841..12785)
                     /gene="mhpB"
                     /locus_tag="ACHY1N_001992"
                     /EC_number="1.13.11.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydroxyphenylpropionate/2,
                     3-dihydroxicinnamic acid 1,2-dioxygenase"
                     /protein_id="HFS4044312.1"
                     /translation="MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPE
                     LVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSG
                     IDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGR
                     FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVIS
                     AAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWV
                     AAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN"
     gene            complement(12787..14451)
                     /gene="mhpA"
                     /locus_tag="ACHY1N_001993"
     CDS             complement(12787..14451)
                     /gene="mhpA"
                     /locus_tag="ACHY1N_001993"
                     /EC_number="1.14.13.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008688 - 3-(3-hydroxyphenyl)propionate
                     hydroxylase activity [Evidence IEA];
                     GO_process: GO:0019622 - 3-(3-hydroxy)phenylpropionate
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="HFS4044313.1"
                     /translation="MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVV
                     EKLDKLIDYPRAIGIDDEALRTMQSVGLVDDVLPHTTPWHAMRFLTPKGRCFADIQPM
                     TDEFGWPRRNAFIQPQVDAVMLEGLSRFPNVRCLFSRELEAFSQQNDEVTLHLKTAEG
                     QRETVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDP
                     VRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYT
                     HNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDAL
                     LDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMR
                     FKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
                     PLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNA
                     SLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA"
     gene            14642..15475
                     /gene="mhpR"
                     /locus_tag="ACHY1N_001994"
     CDS             14642..15475
                     /gene="mhpR"
                     /locus_tag="ACHY1N_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HFS4044314.1"
                     /translation="MQNNEQTEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLH
                     RTTVRRLLETLQEEGYVRRSPSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLR
                     EVVWPTDVSTLDVDAMVVRETTHRFSRLSFHRPMVGRRLPLLKTASGLTWLAFCPEQD
                     RKELIEMLASRPGDDYQLAREPLKLEAILARARKEGYGQNYRGWDQEEKIASIAVPLR
                     SEQRVIGCLNLVYMASAMTIEQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGVHL
                     R"
     gene            15552..16634
                     /gene="lacI"
                     /locus_tag="ACHY1N_001995"
     CDS             15552..16634
                     /gene="lacI"
                     /locus_tag="ACHY1N_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414879.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor LacI"
                     /protein_id="HFS4044315.1"
                     /translation="MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAE
                     LNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERS
                     GVEACKAAVHNLLAQRVSGLIINYPLDDQDATAVEAACANVPALFLDVSDQTPINSII
                     FSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAEREG
                     DWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDT
                     EDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNT
                     QTASPRALADSLMQLARQVSRLESGQ"
     gene            16757..19831
                     /gene="lacZ"
                     /locus_tag="ACHY1N_001996"
     CDS             16757..19831
                     /gene="lacZ"
                     /locus_tag="ACHY1N_001996"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HFS4044316.1"
                     /translation="MTMITDSLVVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPAENPTGCYSLTFNIDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLPSEFDLSTFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PSTQISDFHVATHFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEASDVGFR
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWNKSVDPSRPVQYEGGGADTTATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
                     QQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIE
                     LPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWHLAANLSVTLPSAPHAIPQ
                     LTTSETDFCIELDNKRWQFNRQSGFLSQMWIGDEKQLLTPLRDQFIRAPLDNDIGVSE
                     ATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTVHAWQHQGKTLFISRKT
                     YRIDGSGQMAITVDVEVASDTPHPARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAA
                     CFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGSHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     gene            19883..21136
                     /gene="lacY"
                     /locus_tag="ACHY1N_001997"
     CDS             19883..21136
                     /gene="lacY"
                     /locus_tag="ACHY1N_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="HFS4044317.1"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
                     ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
                     MFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
                     QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
                     FFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
                     KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGF
                     TLISVFTLSGPGPLSLLRRQVNEVA"
     gene            21202..21813
                     /gene="lacA"
                     /locus_tag="ACHY1N_001998"
     CDS             21202..21813
                     /gene="lacA"
                     /locus_tag="ACHY1N_001998"
                     /EC_number="2.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactoside O-acetyltransferase"
                     /protein_id="HFS4044318.1"
                     /translation="MNMSMTERIKAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEV
                     EKRESLIKEMFATVGENAWIEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGA
                     GSVVIKDIPPNVVAAGVPCRVIREINDRDKQYYFRDYKVESSV"
     gene            complement(21916..23097)
                     /gene="cynX"
                     /locus_tag="ACHY1N_001999"
     CDS             complement(21916..23097)
                     /gene="cynX"
                     /locus_tag="ACHY1N_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308421.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanate transporter CynX"
                     /protein_id="HFS4044319.1"
                     /translation="MRNHQKTFTMLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFS
                     VAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGALMRELYPQSALLLS
                     SALLGGVGIGIIQAVMPSVIKRRFQQRTPLVMGLWSAALMGGGGLGAAITPWLVQHSE
                     SWYQTLAWWALPAVVALFAWWWQSAREVASSHKTTTTPVRVVFTPRAWTLGVYFGLIN
                     GGYASLIAWLPAFYIEIGASAQYSGSLLALMTLGQAAGALLMPAMARHQDRRKLLMLA
                     LVLQLVGFCGFIWLPLQLPVLWAMVCGLGLGGAFPLCLLLALDHSVQPAIAGKLVAFM
                     QGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPARFPQLWVKE
                     A"
     gene            complement(23103..23573)
                     /gene="cynS"
                     /locus_tag="ACHY1N_002000"
     CDS             complement(23103..23573)
                     /gene="cynS"
                     /locus_tag="ACHY1N_002000"
                     /EC_number="4.2.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008824 - cyanate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009439 - cyanate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyanase"
                     /protein_id="HFS4044320.1"
                     /translation="MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVT
                     AALLGQQALPADAARLVGAKLDLDEDAILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQ
                     VYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF"
     gene            complement(23604..24263)
                     /gene="cynT"
                     /locus_tag="ACHY1N_002001"
     CDS             complement(23604..24263)
                     /gene="cynT"
                     /locus_tag="ACHY1N_002001"
                     /EC_number="4.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase CynT"
                     /protein_id="HFS4044321.1"
                     /translation="MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRL
                     VPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCG
                     AMTAIASCQCMDHMPAVSHWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANL
                     QTHPSVRLALEEGRIALHGWVYDIESGSIAAFDGATRQFVPLAANPRVCAIPLRQPTA
                     A"
     gene            24373..25272
                     /gene="cynR"
                     /locus_tag="ACHY1N_002002"
     CDS             24373..25272
                     /gene="cynR"
                     /locus_tag="ACHY1N_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CynR"
                     /protein_id="HFS4044322.1"
                     /translation="MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLG
                     VPLFDRSGRTIRLTDAGEVWRQYASRALHELGAGKRAIHDVAALTRGSLRIAVTPTFT
                     SYFIGPLMADFYARYPGITLQLQEMSQEKIEDLLCRDELDVGIAFAPVHSPELEAIPL
                     LTESLALVVAKHHPLAACEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVV
                     IEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAISLAPPLLERTAVLLRRKNSWQT
                     AAAKAFLHMALEECADVGENESR"
     gene            complement(25312..26595)
                     /gene="codA"
                     /locus_tag="ACHY1N_002003"
     CDS             complement(25312..26595)
                     /gene="codA"
                     /locus_tag="ACHY1N_002003"
                     /EC_number="3.5.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine/isoguanine deaminase"
                     /protein_id="HFS4044323.1"
                     /translation="MSNNALQTIINARLPGKEGLWQIHLQDGKISAIDAQSGVMPITE
                     NSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHREGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
     gene            complement(26585..27844)
                     /gene="codB"
                     /locus_tag="ACHY1N_002004"
     CDS             complement(26585..27844)
                     /gene="codB"
                     /locus_tag="ACHY1N_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015209 - cytosine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HFS4044324.1"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVDWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEVNSVE"
     gene            complement(28087..29973)
                     /gene="prpE"
                     /locus_tag="ACHY1N_002005"
     CDS             complement(28087..29973)
                     /gene="prpE"
                     /locus_tag="ACHY1N_002005"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050218 - propionate-CoA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0019629 - propionate catabolic process,
                     2-methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HFS4044325.1"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGSV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDDRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     gene            complement(30013..31464)
                     /gene="prpD"
                     /locus_tag="ACHY1N_002006"
     CDS             complement(30013..31464)
                     /gene="prpD"
                     /locus_tag="ACHY1N_002006"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047547 - 2-methylcitrate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0019679 - propionate metabolic process,
                     methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="HFS4044326.1"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTAMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRTRLEQMPVNEYLDLYVI"
     gene            complement(31498..32667)
                     /gene="prpC"
                     /locus_tag="ACHY1N_002007"
     CDS             complement(31498..32667)
                     /gene="prpC"
                     /locus_tag="ACHY1N_002007"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050440 - 2-methylcitrate synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HFS4044327.1"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAEHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRPFVALDKRQ"
     gene            complement(32712..33602)
                     /gene="prpB"
                     /locus_tag="ACHY1N_002008"
     CDS             complement(32712..33602)
                     /gene="prpB"
                     /locus_tag="ACHY1N_002008"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046421 - methylisocitrate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019629 - propionate catabolic process,
                     2-methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HFS4044328.1"
                     /translation="MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDDLFARSQVK"
     gene            33841..35427
                     /gene="prpR"
                     /locus_tag="ACHY1N_002009"
     CDS             33841..35427
                     /gene="prpR"
                     /locus_tag="ACHY1N_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HFS4044329.1"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMRQGQFRRDLFYRLSILR
                     LQLPPLRERVADILPLAESFLKVSLAALSAPFSAALRQGLQASETVLVHYDWPGNIRE
                     LRNMMERLALFLSVEPTPDLTPQFLQLLLPELARESAKTPAPRLLTPQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     gene            complement(35525..35800)
                     /gene="yahO"
                     /locus_tag="ACHY1N_002010"
     CDS             complement(35525..35800)
                     /gene="yahO"
                     /locus_tag="ACHY1N_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 family periplasmic protein YahO"
                     /protein_id="HFS4044330.1"
                     /translation="MKIISKMLVGALALAVTNVYAAELMTKAEFEKVESQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     gene            35947..36618
                     /gene="yahN"
                     /locus_tag="ACHY1N_002011"
     CDS             35947..36618
                     /gene="yahN"
                     /locus_tag="ACHY1N_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HFS4044331.1"
                     /translation="MMKLLHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQT
                     SLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAW
                     CSMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTW
                     ARLMAWAGIVLASVIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYE
                     GVTQR"
     gene            complement(36635..36880)
                     /gene="yahM"
                     /locus_tag="ACHY1N_002012"
     CDS             complement(36635..36880)
                     /gene="yahM"
                     /locus_tag="ACHY1N_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YahM"
                     /protein_id="HFS4044332.1"
                     /translation="MAVQLFKTLLNQIPLLSSLQSGTLPLFGYSGRVRPMKKAHTGES
                     GLKWEAKDSSKLIGNKDHALRGLSSPMAGIRQIRLIT"
     gene            complement(37293..38108)
                     /gene="yahL"
                     /locus_tag="ACHY1N_002013"
     CDS             complement(37293..38108)
                     /gene="yahL"
                     /locus_tag="ACHY1N_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YahL"
                     /protein_id="HFS4044333.1"
                     /translation="MISLKAPHNNLMPYTQQSILNTVKNNQLPEDIKSSLVSCVDIFK
                     VLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWSDDNALTINVQFNDFPGFYDWMD
                     YPDHPVKFVFRILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLVQFIDSVRTDC
                     KCILLEHHMPLLRIFPKGKECMHVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIYP
                     VFPESLVMLLLSVLDVKTYRDDARLNQWISNRVQELGDRYYPVNKHVKIRYTL"
     gene            complement(38351..39400)
                     /gene="yahK"
                     /locus_tag="ACHY1N_002014"
     CDS             complement(38351..39400)
                     /gene="yahK"
                     /locus_tag="ACHY1N_002014"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase YahK"
                     /protein_id="HFS4044334.1"
                     /translation="MKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDL
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALG
                     ADEVVNSRNADEMAAHLKSFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     gene            complement(39487..40443)
                     /locus_tag="ACHY1N_002015"
     CDS             complement(39487..40443)
                     /locus_tag="ACHY1N_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4044335.1"
                     /translation="MKKSWRNNVEFYLIGLLALTVAAFSITMPEIFWSISNFQSVASQ
                     MPVLGILALAMAVTMLCGGINLSIIATANACSLVMAWVATQYPPGIATVVATLLAGAG
                     AAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGINILVTGGSAIANYPSWVLWLNHAQ
                     WFGIPLPMWLFAAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVI
                     SALLCAVAAFLMMSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFL
                     LQIIESGFNILGISPYLTMALWGTLLLCFIQARGMLGLDRVV"
     gene            complement(40440..41411)
                     /locus_tag="ACHY1N_002016"
     CDS             complement(40440..41411)
                     /locus_tag="ACHY1N_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4044336.1"
                     /translation="MAELKKRHEFWLALLIVVLFVGLAWRSDEFLTFGNLYDLANNYA
                     MLTILACGLFVVLISGGIDISFPAMTIIAQYGMVLLLQKIGGNFAVAFALAGCIGILL
                     GLINALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEQGVMLFKYTDA
                     DGYDYGLGLPLIAMITVVLLTAFIMNFTSVGRKIYALGGNRESASRIGFSVLKLQLFV
                     YGYMGLMSGAAGVVQSWTVMTVAPDSLLGYELTVLAAVVLGGTSLLGGRGTLTGTLLG
                     VVLLAVMQNGLNLLGVSSYWQTLITGIIIVASISATAWSQHQNRSLL"
     gene            complement(41404..42888)
                     /locus_tag="ACHY1N_002017"
     CDS             complement(41404..42888)
                     /locus_tag="ACHY1N_002017"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308402.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HFS4044337.1"
                     /translation="METFLSLRHINKTFHATRALRDVSLDFMSGEVHCLAGQNGCGKS
                     TLIKIMSGVYRPDEGAEITLGGKNWSKLTPAASVAQGIQVIYQDLSLFPNLSVWENIA
                     VNHYHHGLFVNRRRLREVAQAAMTSINVTLPLDTLVSELSIARCQLVAICRALAQDAR
                     LIVMDEPTASLTHQEVQGLLQVVHQLRERGICVVFVSHRLEEVMEVSDRISVLKDGEL
                     VGTFPAAEMTTKQLGFLMTGQEFEYQVRELWQGKSSTPVLEVRNLSRHGEYLNINLRV
                     EAGEVVSIVGLLGAGRTELCLSLFGMTRPDAGEILINGQPVTLHSNQDAIRHGIGYVS
                     EDRMSRGLVMAQSIEDNIISTVFHKVKDRFGFLSETKVRDLVDRLIKALTIKVSDPHL
                     PVNTLSGGNAQRVSIAKWLAIGPRLLILDSPTVGVDIANKAGIYGIISDLAAHGIAVL
                     MICDEIEEAWYQSHRILVMQKGQITHSFLPDSSSQARIAEVVNG"
     gene            complement(42937..43920)
                     /locus_tag="ACHY1N_002018"
     CDS             complement(42937..43920)
                     /locus_tag="ACHY1N_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4044338.1"
                     /translation="MNKRFVINMVSSLLLGAALISAPLQAAEKVVVNISKVDGMPWFN
                     RMGEGVVEAGKAFGVNASQVGPSSTDAPQQVKIIEDLIARKVNAITIVPNDANVLEPV
                     FKKARDAGIVVLTNESPGQPSANWDIEIIDNEKFAAEYVEHMAKRMGGKGGYVIYVGS
                     LTVPQHNLWADLLVKYQKEHYPDMHEVTRRMPVAESVDDSRRTTLDLMKTYPDLKAVV
                     SFGSNGPIGAGRAVKEKRAKNKVAVYGMMIPSQAASLIKSGDITEGITYDPASAGYAL
                     AAVASTLLKGEEIKPGLEMQNLGKADVDMDKRIIRFHKVLLVNKDNIDSLY"
     gene            complement(44175..44585)
                     /locus_tag="ACHY1N_002019"
     CDS             complement(44175..44585)
                     /locus_tag="ACHY1N_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFS4044339.1"
                     /translation="MTIKEKFSQKYPHASFCTFGDSAALADHLATLIATGVKTASCGS
                     LAGCIEDNAFPMIGEYKIVENSRGEPVCVIRVIGLHLLRFSDVTVELARKEGEGDLSL
                     EYWRNEHRRFFQAEGSYSPEMDVIFEEYALIDVV"
     gene            complement(44884..46266)
                     /gene="yahJ"
                     /locus_tag="ACHY1N_002020"
     CDS             complement(44884..46266)
                     /gene="yahJ"
                     /locus_tag="ACHY1N_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFS4044340.1"
                     /translation="MKESNSRREFLSQSGKMVTAAALFGTSVPLAHAAVAGTLNCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQDGKIVALRENKQHPDAT
                     LPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFECEIVAFP
                     QHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPSGVTAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDALANRMAAQQISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVWGSVAG"
     gene            complement(46276..47226)
                     /gene="yahI"
                     /locus_tag="ACHY1N_002021"
     CDS             complement(46276..47226)
                     /gene="yahI"
                     /locus_tag="ACHY1N_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase family protein"
                     /protein_id="HFS4044341.1"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSESQRDKLQKANPDWCFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTEAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
     gene            complement(47369..48787)
                     /gene="yahG"
                     /locus_tag="ACHY1N_002022"
     CDS             complement(47369..48787)
                     /gene="yahG"
                     /locus_tag="ACHY1N_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HFS4044342.1"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKIAAANQQALERIIQSHPVLIGFDQAINVVPGMTPKTILHAG
                     PPITWEKMCGAMKGAVTGALVFEGLAKDLDEATELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPMLRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
     gene            complement(48787..50334)
                     /gene="fdrA"
                     /locus_tag="ACHY1N_002023"
     CDS             complement(48787..50334)
                     /gene="fdrA"
                     /locus_tag="ACHY1N_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HFS4044343.1"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKAGADNEQLLVEIEELFNTKAQSGSHEARYA
                     TIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIVLISKPPAPAVARKVLERARACRK
                     PVVVCFLGRGETPVDEQGLQFARGSKEAALKAVMLSGVKQEHLDLHTLNQPLIADVRA
                     RLQPQQKYIRGLFCGGTLCDETMFAVMEKHGDVYSNIQPDPEFRLQDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     gene            complement(50324..51187)
                     /gene="yahE"
                     /locus_tag="ACHY1N_002024"
     CDS             complement(50324..51187)
                     /gene="yahE"
                     /locus_tag="ACHY1N_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HFS4044344.1"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFDDLFRHGDKVQFDDQGITVGQHLHIEMSRCRRWLSPTLQMTAV
                     NFHLIAWQQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNEKQNI
                     AAAVASMIGLGIGLTPSADDYLTGLALILFIPGHPSEKYKEEFYLGMQRGRNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     gene            complement(51227..51832)
                     /gene="yahD"
                     /locus_tag="ACHY1N_002025"
     CDS             complement(51227..51832)
                     /gene="yahD"
                     /locus_tag="ACHY1N_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HFS4044345.1"
                     /translation="MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
     gene            52090..52587
                     /gene="yahC"
                     /locus_tag="ACHY1N_002026"
     CDS             52090..52587
                     /gene="yahC"
                     /locus_tag="ACHY1N_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HFS4044346.1"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGSKSGFIRSLAVNYSGMVWAFFAALAAGWLASVSGLSAFWASVITTVPFSAVV
                     VWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATT
                     KRDGY"
     gene            52679..53611
                     /gene="yahB"
                     /locus_tag="ACHY1N_002027"
     CDS             52679..53611
                     /gene="yahB"
                     /locus_tag="ACHY1N_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4044347.1"
                     /translation="MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRME
                     TGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFYAIKRSIDTISQGIEARVRICIN
                     QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
                     GIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLH
                     GQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMTQSLLVTRQIHNPRQDSRMLLAT
                     QHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN"
     gene            complement(53653..54741)
                     /gene="pdeL"
                     /locus_tag="ACHY1N_002028"
     CDS             complement(53653..54741)
                     /gene="pdeL"
                     /locus_tag="ACHY1N_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFS4044348.1"
                     /translation="MASHDLSVFLEEFGATVNLTLPGIVSEKERLLLKLLMEGMSVTE
                     ISQYRNRSAKTISHQKKQLYEKLGIQSDITFWRDIFFQYHPQVISGTGNKNNFYIPDN
                     RCHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEGLVRWEHPQTGIIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
     gene            complement(54883..58866)
                     /gene="ehaA"
                     /locus_tag="ACHY1N_002029"
     CDS             complement(54883..58866)
                     /gene="ehaA"
                     /locus_tag="ACHY1N_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin EhaA"
                     /protein_id="HFS4044349.1"
                     /translation="MNKIYRLKWNRSRNCWSVCSELGSRVKGKKSRAVLISAISLYSS
                     LVFADDVIVNQDKAIDFGKENQSIDYRITVTDNANLVINTTDTSRPRLTLASGGGLDI
                     TGGKVTINGPLNFLLKGTGFLNVSNAGSELYADDLYESNSGMRHDQGYFNVSNGGKIH
                     VKGTSRLTYTQGNVSGEGSQVNAGTFFMGVYGGYGGNQFLSVNNGGEVNAREHISLGY
                     YDQRSDTTLVVSDGGKISAPKISLSTNSELALGAQEGSAAKAAGIIDAEKIEFVWAKT
                     SDKKITLNHTDKNATISADIVSGSEGLGYINALNGTTYLTGDNSAFSGKVKIEQNGAL
                     GITKNIGTAEINNRGKLHLKADDSMTFANKISGNGTISIDSGTVALTGNNYAFSGYID
                     VASGAVAVISEDKNIGRADLDVDGKLQINANKDWVFDNDLQGRGIVEINMGNHEFSFD
                     EFAYTDWFQGSLAFQNTTFNLEKNAEFLQRGGITAGQGSLVTVGKGAHSISTLGFSGG
                     TVDFGALTAGAQMTEGTVNVSKTLDLRGEGVIQVSDSDVVSSVSRDIDSALSLTEVDD
                     GNSTIKLVDAQGAEVLGDAGNLQLQDKNGQILSSSAQRDIQQNGQKAAVGTYDYRLTS
                     GVNNDGLYIGYGLTQLDLHATDSDALVLSSNGKSENAADLSAKITGSGDLAFSSQKDQ
                     TVSLSNKDNDYTGVTDLRSGTLLLNNDNVLGNTHELRLAAETELDMNGHSQTVGTLNG
                     SADSLLSLNGGSLTVTNGGTSTGSLTGSGELNIQGGTLDIAGDNSNLTANVNIANSAN
                     VLVSHAQGLGSANVENNGTLALNNSAEKRAAASVNYTLGGNLTNNGTLMTGMSGQQAG
                     NVLVVKGNYHGNNGQLVMNTVLNGDDSVTDKLVVEGDTSGTTAVTVNNAGGTGAKTLN
                     GIELIHVDGKSEGEFVQAGRIVAGAYDYTLARGQGANRGNWYLTSGSDSPELQPEPDP
                     MPNPEPNPNPEPNPNPTPTPGPDLNVDNDLRPEAGSYIANLAAANTMFTTRLHERLGN
                     TYYTDMVTGEQKQTTMWMRHEGGHNKWRDGSGQLKTQSNRYVLQLGGDVAQWSQNGSD
                     SWHVGVMAGYGNSDSKTISSRTGYRAKASVNGYSTGLYATWYADDESRNGAYLDSWAQ
                     YSWFDNTVKGDDLQSESYKSKGFTASLEAGYKHKLAEFNGNQGTRNEWYVQPQAQVTW
                     MGVKADKHRESNGTLVHSNGDGNVQTRLGVKTWLKSHHKMDDGKSREFQPFVEVNWLH
                     NSKDFSTSMDGVSVTQDGARNIAEIKTGVEGQLNANLNVWGNVGVQVADRGYNDTSAM
                     VGIKWQF"
BASE COUNT        14106 a        16016 c        14741 g        14276 t
ORIGIN      
        1 tacaaacact taacatatga attgcataga aacattaccc agtcgaacct ccgggtctga
       61 aagcccttgc ttttcagtta ttagcaacat ttaacattta taaattaaca tctggctgcg
      121 ccagagatta cgtctctgag tgcatcgttg tgcttgtagt ataataaata aaatggagtg
      181 tcattaagtg gataaggttt tagattcagc cctcctttct tcggcaaata aaagaaaggg
      241 tatccttgct attggcgcac atcctgacga tatagaatta ggctgtggcg catcgcttgc
      301 tcgtcttgcg caaaaaggaa tttatatcgc agccgtggtg atgactaccg gcaactctgg
      361 cacagatgga ataatcgatc gccatgaaga atcgcgcaac gccctaaaga tattagggtg
      421 ccaccaaact attcatctta attttgctga cacccgcgct catttacagc tcaatgatat
      481 gatttccgcc ctggaagaca tcattaaaaa tcaaattcct tctgatgttg aaatcatgcg
      541 ggtatatacc atgcatgatg ccgaccgcca tcaggatcat ctcgctgttt atcaagcttc
      601 aatggttgcc tgccgcacta ttccacaaat tctcggctac gaaaccccaa gtacctggct
      661 ttcatttatg cctcaggttt ttgaatccgt taaagaagaa tatttcacag tcaaacttgc
      721 tgcattaaaa aaacataaaa gccaggaacg acgcgattat atgcgtcatg atcgcctgcg
      781 tgcagttgca caatttcgcg ggcaacaggt caatagcgat ctgggtgaag gctttgtaat
      841 tcataaaatg attctttgag caaattgcat gaaaacctgg atatttatct gtatgtccat
      901 agcaatgttg ctatggtttt taagtacgct aagacgtaaa cccagtcaaa agaaaggctg
      961 tattgacgcc attatacctg cgtataacga aggcccgtgt ctggcgcagt cactggataa
     1021 tctactgcgt aacccttatt tttgccgggt aatttgcgtt aacgacggct ccacggacaa
     1081 taccgaagcg gtcatggcgg aagtcaaacg caaatggggc gaccgctttg ttgccgtcac
     1141 gcaaaaaaat accggtaaag gtggtgcgct gatgaatggc ctcaattatg ccacctgcga
     1201 ccaggttttt ttaagtgatg ccgacaccta tgttccgccc gatcaagacg gaatgggcta
     1261 tatgctggca gaaattgagc gcggtgctga tgccgtaggc ggcattccct ctactgcgtt
     1321 gaaaggcgcg gggctgttac cgcacatccg cgcgaccgta aagttgccga tgattgttat
     1381 gaagcgcacg ctacagcagc tcctgggcgg cgcaccgttt attatcagcg gtgcctgcgg
     1441 aatgttccgc actgatgtat tgcgtaagtt cggtttctca gatcgtacta aagtcgaaga
     1501 ccttgatctc acctggacat tagtggcaaa cggctaccgt attcggcagg cgaatcgctg
     1561 catcgtatac ccacaggaat gcaacagccc gcgtgaggag tggcgtcgct ggcggcgttg
     1621 gattgtggga tacgcggtct gtatgcgcct gcataaaaga cttttattta gccgcttcgg
     1681 tatcttcagt atatttccta tgctgttggt tgtgatttat ggcgttggga tttatctcac
     1741 tacctggttt aatgaattca tcaccaccgg gccgcatggt gtggtgttgg caatgtttcc
     1801 gcttatctgg atcggcgtag tttgtgttat tggtgctttt agcgcctggt ttcatcgttg
     1861 ctggttgttg gtgcctttag cgccgctttc cgttgtgtat gtattattag cttatgccat
     1921 ctggattatt tatggactta ttgccttttt tactggacgc gaacctcagc gcgacaaacc
     1981 cacccgctat tccgcactgg tggaagcgtc aaccgcttat tcccaacctt ctgtcacagg
     2041 aactgaaaaa ctatctgaag cttaatgtta aagagaaaaa tattcagatt gcagaccagg
     2101 taattattga tgaaactgca ggtgaagttg ttatcggcgc gaatacccgt atttgtcatg
     2161 gtgccgttat tcagggtccg gtagtgattg gcgcaaactg cctgataggt aattatgcgt
     2221 ttattcgtcc tggcacaata atcagcaatg gtgtaaaaat tggttttgcc accgaaatta
     2281 aaaatgcggt tattgaagcg gaagcaacga ttggtccgca atgttttatt gccgactcgg
     2341 tagttgcaaa ccaggcatat ttgggcgcac aagtacgtac cagtaatcat cgtctggatg
     2401 aacagcctgt gtctgttcga actccagagg gaattatcgc taccggatgc gataaattag
     2461 gttgttatat cgggcagcgt tcacgccttg gcgtacaagt tataattttg cctgggcgaa
     2521 ttatttcccc gaacacgcaa cttggcccgc gcgtgattgt agaacgtaat ttacctgccg
     2581 gaacttattc actccgacaa gaacttatcc gtacaggaga ttaaaatgat aaaacggacg
     2641 ttattagcgg cggccatttt tagcgcattg cccgcttatg ccgggttaac ttccattacc
     2701 gcgggctacg attttaccga ttattctggc gatcatggca accgtaattt agcgtatgct
     2761 gaactggtgg cgaaagttga aaacgcaacg ctgcttttta atctttccca ggggcgtcgt
     2821 gattatgaaa ctgaacattt caatgccact cgcggtcagg gtgcggtctg gtataaatgg
     2881 aataactggc tgacaacccg aacgggtatt gcctttgcgg ataatacgcc ggtctttgcc
     2941 cgccaggatt ttcgtcagga tattaacctg gccctgttgc caaaaacgct tttcacgacc
     3001 ggttatcgct acactaaata ttacgatgat gtcgaagtcg atgcctggca aggcggcgta
     3061 tcactctata ctggcccggt gatcaccagc taccgctata cccattatga ctccagcgat
     3121 gcaggtggta gttatagcaa tatgatttcc gtgcgtctga atgacccgcg cggcactggt
     3181 tatacgcaac tatggctaag ccgcggaaca ggcgcttaca cctatgactg gacgccagaa
     3241 acacgctacg gcagcatgaa gagcgtcagt ttgcaacgta ttcaaccgct gactgagcaa
     3301 cttaatctcg ggctgacggc aggtaaagtg tggtacgaca ccccaaccga tgattataac
     3361 ggtctgcaac ttgcagccca tctgacctgg aaattctgat tccttctgcc gcccgctatc
     3421 cggggcggcc ttccctgccg attagccccc cctttcctct ttgttttccg accacattca
     3481 ccggataaat tttattctcc agtgttatat actatagggg ggtatgcatt gacatatagc
     3541 atacccccct atagtatatt gcgtgcagat gatgaggtgc gaaatgccca gtactccgga
     3601 agagaagaaa aaggtcctta ctcgagttcg tcgtattcga gggcagattg atgctctgga
     3661 acggtcgctg gagggtgatg ccgaatgccg tgccatactc caacagatcg ctgccgttcg
     3721 gggcgcggct aacgggctga tggcagaagt gcttgaaagc catatccggg aaacgtttga
     3781 ccgaaatgac tgctacagcc gcgaagtcag ccaatccgtt gacgacacta ttgaactggt
     3841 tcgagcctat cttaaatagc tgaatctatt accatattga ggaagagcga gagatgaaat
     3901 cacgtgctgc cgttgcattt gctcccggta aaccgctgga aatcgttgaa attgacgttg
     3961 caccaccgaa aaaaggtgaa gtgctgatta aagtcaccca taccggcgtt tgccataccg
     4021 acgcatttac cctctccggg gatgacccgg aaggtgtatt cccggtggtt ctcggtcacg
     4081 aaggggccgg cgttgtggtt gaagtcggtg aaggcgtaac cagcgtcaaa cctggcgacc
     4141 atgtgatccc gctttacacc gcggagtgcg gcgagtgtga gttctgtcgt tctggcaaaa
     4201 ctaacctctg tgttgcggtt cgcgaaaccc agggtaaagg cttgatgcca gacggcacca
     4261 cccgtttttc ttacaacggg cagccgcttt atcactacat ggggtgctct acattcagtg
     4321 aatacaccgt ggtcgcggaa gtgtctctgg ccaaaattaa tccagaagca aaccatgaac
     4381 acgtctgtct gctgggctgt ggcgtgacca ccggtattgg cgcggtgcac aacacagcta
     4441 aagtccagcc aggtgattct gttgccgtgt ttggtcttgg cgcgattggt ctggcagtgg
     4501 ttcagggcgc gcgtcaggcg aaagcgggac ggattatcgc tatcgatacc aacccgaaga
     4561 aattcgatct ggcgcgtcgc ttcggtgcta ccgactgcat taacccgaat gactacgaca
     4621 aaccgattaa agatgtcctg ctggatatca acaaatgggg tatcgaccat acctttgaat
     4681 gcatcggtaa cgtcaacgtg atgcgtgcgg cgctggaaag tgcgcaccgc ggctggggtc
     4741 agtcggtgat catcggggtg gcaggttctg gtcaggaaat ctccacccgt ccattccagt
     4801 tggtcactgg tcgcgtatgg aaaggttccg cgtttggcgg cgtgaaaggt cgttcccagt
     4861 taccgggtat ggttgaagat gcgatgaaag gtgatatcga tctggaaccg tttgtcacgc
     4921 ataccatgag ccttgatgaa attaatgacg ccttcgacct gatgcatgaa ggcaaatcca
     4981 ttcgaaccgt aattcgttac tgatttcccg caggtatacc ccgtccactt cagacggggt
     5041 tcttaatact ctccccgggc agccgtccgg gggattaacc gtgagataat gactgatgga
     5101 actcattgaa aaacatgcca gctttggcgg ctggcaaaat gtgtatcggc attattccca
     5161 atcactgaaa tgtgaaatga atgtcggcgt ctatctccca ccaaaagccg cgaatgaaaa
     5221 attgccggtg ctgtactggc tttcgggcct gacctgcaac gagcagaatt tcattactaa
     5281 atcggggatg cagcgttacg cggctgaaca caacattatt gttgttgcgc cggacaccag
     5341 tccgcgaggc agtcatgtcg cagatgccga ccgttacgat ctcgggcaag gtgccgggtt
     5401 ttacctgaac gcaacgcaag cgccgtggaa tgaacattac aaaatgtatg actatatccg
     5461 caacgagctg ccggatttag tgatgcaaca ttttccggca acgaccagaa agtctatctc
     5521 tggtcattct atgggcgggc tgggcgcgct ggtgctggcg ttacgtaacc cagatgaata
     5581 tgtcagcgtc tcggcgtttt cgcccattgt ctccccatcg caagtaccgt ggggacagca
     5641 agcctttgcc gcatatcttg gtgaaaataa agatgcctgg ttgaattacg atccggtgag
     5701 tcttatttca caaggtcaac gcgttgcgga aatcatggtt gatcaggggt tgagtgatga
     5761 tttttacgcg gaacagctgc ggactccaaa tcttgaaaag atctgccagg agatgaatat
     5821 caagacgtta atccgttatc acgagggtta cgaccacagc tattattttg tctccagttt
     5881 tattggcgag catattgcct accacgccaa taaactgaat atgcgttgat aatagtgcac
     5941 gactgccgga tgcggcgtga acgccttatc cgcctacatt tcgcccgcag gccgtaggca
     6001 tgataagacg cgcatagcgt cgcatcaggc atctgcgcac gacttatcta tgtttaccac
     6061 atcaaatcat caggcacttt gaagtcggca tatgggtcgt cttcatcctg ctcttcggca
     6121 ctgagcgcgc tgtgcaacac aatactgctg gcatcacgct gagcaatttt atcggcaacg
     6181 ctggcgggaa taatggcgta ttcaccttcg ctattgttat cgaccaacaa gcgggcaatc
     6241 gccagacgac cattaatcaa ctgcgcctgt gtgagcttat cgacaaaaat cttcttaatc
     6301 agattgccgt cagtgaagtt aaaaccaata tcaccattgg caatggtgat tcggttcatt
     6361 tcaataagct gcttcacctg ggctttatat tctttcgcca acgccgcttg tttttgctgt
     6421 tcgctaagct gtttatcacg ctcaagctgt gcctttttat tttcttctac cgccgcccga
     6481 gcttcacgcg cctgaacgcg cgattttttc gccgttctct cgaccttcgc cgcttttttg
     6541 ctggtgacta atcctgcttt gagcaactgc tcttgtaagg taagttttgc catctttgtt
     6601 tccaaacccg ctgaataatt tttagcgagt atacctgtaa acgccgtggg tgtattgggg
     6661 gcaagtccct ttcgcccctg ctaaataagg cgcgtcaggc atcggcacac ggctgcattc
     6721 ttgatctccg actcatcaaa ataaacaccg ccaacccagc aacaagaata cccggtgcag
     6781 aagcggccat tacgccgacc gtgccagtgc ctaatgccag cattttcccg gccagtaacg
     6841 gaccgctcat agcccccaga cgccctaccg ccacggctgt tcccacacct gttgcgcgga
     6901 tctgcgaact gtaaaacaac ggtgccaggg catacaaaac gctttgccca cctgtcgcaa
     6961 acaaccccgc gacaaatccc gccagcaaca taccgttaaa tgacgacacc gttccaagcg
     7021 ccagcagcga agctaacatg ccgctataaa tcagtagcga catggttact ggacgcagct
     7081 tatccatcaa tgcgcccaac attaacgtcc cgcttgccgc ccccatttgc agggcaaaca
     7141 tcacccctgc cgcctgcgat ggctggaatc cttgctccac caaaagtagc ggtagccagt
     7201 tgatcaacat ataaaccacc agcagagtga agaaataaca caaccacagc agcagcgtcg
     7261 cggttgccgt ttctggcgca aataaggcac gcagtggtgg cgcagcctgt ttttcgccag
     7321 cgaaaaccgc tgactccggc agccagcgca ttaatagcgg caccagaatc aacggcacca
     7381 caccacctac ccaaaacacc gtttgccatg ctaagtttgc ccccgcgaaa cccagtgtcg
     7441 ccgccagcgc cgcgccaatg ggaacaccgc aatacatcag gctcactgcc gtcccacgaa
     7501 aacgtggacc cgcggcttca gacgtcaggg cgataagatt cggcaacgcc gcccccagcc
     7561 cgacaccggt catcagccgc gcaaagacca gtgaggggaa atcccaggca atcgccgttg
     7621 ccagtgagaa caaaccaaac agcgcaactg agccaatcaa aatactctta cgaccataac
     7681 ggtctgccag catcccgcca accaacgcgc cgggtagcaa accgagtatt ccggcgctaa
     7741 atatccagcc catttgcatt ttatcgagtg cgaaagcctg ggcgatgcca cccgccgcaa
     7801 tgccagccgc ctgaagatcc agcccttcca tcagagcgac caaaaaacaa agcccgatgg
     7861 tcagcatcag gcgggatgaa gatgatgaag gggtacgagt cgacataaga tgaacctcgt
     7921 tgcgagtgca ggtgaatcgc gactgataca ttgccagccg cgtaatcaga actatttaat
     7981 gactgcctac gggcgaaatg taggccggac aagacgttta tcgcatccgg cagtcgtgtg
     8041 cagatgcctg atgcgacgct aacgcgtctt atcaggccta caaattctca cgccacccgt
     8101 aggccggata aggtgtttac gccgcatccg gcagtcgtgc tgggatgggc atacaaaatg
     8161 cacgttctcg gcagtcatca ttatttgttg ttgcgcagat ccagcgccac gtcaacgatc
     8221 atatcctcct ggccgccaac catccggcgt ttgcccagct caacgagaat atccaccgca
     8281 cttaagccat aacgcgccgc cgccgtttca cagtgacgca ggaagctcga gtaaacacca
     8341 gcgtatccca gcgccagcgt ttcgcgatcg actcgtaccg gtcgatcctg caacggacgc
     8401 accaggtcgt cagcggcatc cattaacgca tagagatcgg tcccatgctg ccagcccagt
     8461 ttatccgcgg cggcaataaa cacttccagc ggtgcgttac ctgcgcccgc gcccattccc
     8521 gcgaggctgg cgtcgattcg gtcgcagccc tcttccaccg ccgcgataga gttcgccacg
     8581 ccaagactca ggttatggtg agcgtgcatg ccagtttgcg tttctggttt cagctctgct
     8641 ttcagggcgc ggaaacggtc acggatatcg ctcatgttca tcgcaccgcc agaatccacc
     8701 acataaatac aggtcgcacc gtagccttcc atcagctttg cctgctttgc gagattctcc
     8761 ggcgtggtca tatggctcat catcagaaaa ccaacggtgt ccattccgag ctcgcgggca
     8821 tactgaatat gctgggcgga aacatcagct tcggtacagt gcgttgccac acgaaccacc
     8881 cgcgcgccag cctgccaggc atttttcaga tcgtgaatag tgccgattcc tggcagcaac
     8941 aacgtcgcga ttttggcgtg cttcaccaca tccgccgctg cttcaatcca ttcaaggtcg
     9001 ctatgtgcgc cgaaaccata gttaaagctg gaaccctgca aaccgtcgcc atgggccact
     9061 tcaatcgaat ccacgcgggc atcgtccagt gctttggcaa tctggcgaac gttttccagc
     9121 gaatactgat gacgaatggc gtgcataccg tcacgcaacg tgacgtccga gatataaagt
     9181 tttttaccgt tcatgccgct tctcctgcct tgcgcgccag tgactgggcc attttttccg
     9241 ctgtcgccag cgcactggaa gtcataatgt cgaggttgcc cgcataggca ggcagataat
     9301 gcgctgcgcc ttcgacttcc agccagaccg ctgttttcag tccggagaat tgccccacgc
     9361 ccggtaaatt gaccggttta tcctgcggga taacttcaaa ctgcacgcgc tgtttcaggc
     9421 gataacccgg tacgtaagcc tgcaccgcct cagccatttc attgattgag gcttcgatat
     9481 catcttgtga agcttcgtcg ctcaatacat acaccgtgtc acgcatcatc aacggtggct
     9541 ctgctgggtt aagcacaata atcgccttcc cttttgccgc gccgcccacc acttcaatgg
     9601 ctcgggaagt ggtttccgta aattcatcga tattggcacg cgtgccaggt ccggcagatt
     9661 tactggcgat agaagcgata atttcggcgt aatgaacacg cgccacgcgt gaaactgccg
     9721 ccaccattgg aatggtggcc tggccgccgc aggtgaccat gttgacgttc agttgatcga
     9781 cgttcgcctc gaggttaacc accggcacgc agtaagggcc gatggcagca ggcgtcaggt
     9841 caattaagcg aatatccggt ttcgcttcgc gtaaagcggc atcgtttttc acatgcgcgc
     9901 ccgcgctggt cgcatcaaat acaatgtcga tatcagcaaa ttcaggcatg ttcatcagcc
     9961 cgatcacccc ttcatgggtg gtggcgacgc ccatacgtct ggcacgcgcc agaccgtcgg
    10021 actgaggatc aatgccgacc atcaccgcca tctccagatg ctgaccgtga cgcaaaattt
    10081 taatcatcag atcggtgcca atgttgccag aaccgataat ggcgacttta cgcttactca
    10141 tgacagactt ccttttgggg ctgcgcttga aaatgtcgca gcaactgaac ctatgccttc
    10201 aatatgggct tcaaaacgat cgcccgcatt cactgccacc atcggaccta atgccccggt
    10261 aagaatgata tctccggcgc gcagcggttc acccaggctg gccattttgc gtgccagcca
    10321 gacggcggca ttaagcggat gtcccaggca ttcgctgccg cgcccgctgg aaacctcttc
    10381 gttattacgc gtcatcttca tggcgcagtt tttcaggtct aaccccgccg gacgttgcgc
    10441 cggaccgccg atgacataca ccccgcagga agcgttatct gccacggtat cgacaaactg
    10501 aatcgaccag tcgcgaatgc ggctacccac cacctccagc gccggaagta cccattcaat
    10561 ggcgttatac agttcgtcga aggtgatatc ggttgcgggc aaatcgcggt tcaacaccag
    10621 tgcgatctcc gcttcaatgc gggcttgcag aacacgggaa aaaggaatga tttcgttatc
    10681 gccataacac atgtcggcaa ataatgtccc aaaatccggt tgatcaacgc ccagttgttg
    10741 ctgcactttc ggatgcgtca ggcccacttt acgccctacc acgcgacgcc cctgcgcaac
    10801 gtcatattgc acatttatgt gctgaatggc gtaggccgct tcagcgttat cgataccaat
    10861 cagatcgcgc agcggcgcaa tcgcttcgcc ctgctctgcg gcgcggcgta aatccgccgc
    10921 cagttgctca agagtatgct tcgtcatgac cattccttaa gggcgtgcga ggaaattcag
    10981 caccaattga ttgaaagcgt cggcatgttc ccactgcgtc cagtgaccac agtcgcggaa
    11041 gatatgcagt tcagaaccgg caatgccgga cagcagacgc agacccgcat ccatcggcac
    11101 aaagcggtcg ttgcgccccc agacaatcag ggtttgcgct ttgatttccg ccagacgtgg
    11161 gccaaaatcc gggaactgtt tcggattagc ttccaggctc ttaacgaagt tttccaggtg
    11221 atcgcggcgc gacagcatat tattcaggcg cgcttcaaac agggcgtcgg tcaaatcgct
    11281 ggtatcgaaa acgaagatat ccatcatcag cttcaggttt tcgatagtcg gctgacgata
    11341 aagctgattc agtcgcttaa taccttcggt tggcatcggc gtaaacaaac tcatgccgcc
    11401 cgtaccgccg cccatcagca ccagtttgcc gacgcgctcc ggccagttaa gggtgaacgc
    11461 catagaacta tggccgccca tcgagttgcc cagcaggtgg attttggcga tatccagttg
    11521 atccaccacg cttttcagga ttcgtgcatt aagatccgat cgtgaaccac tattaacgat
    11581 cgaatcgctt ttgccccaac ccggacaatc cagcaggatt acccgatagc ccgcctctac
    11641 cagcggatcg atattgcggc tgaagttcgc ccagccagta gcacccgggc cggaaccgtg
    11701 cagcaggaca acggtttcgt cgccttgtcc gcagtcatta aaatggatgc gcagcgtttt
    11761 acccgcttct tctacattca gaaaacggct ggtggcggct tcggtttgtg gctgataact
    11821 catcatcttc tcctgcatat tcagttctct gttctggcgc ttaacgagcc aaatccggca
    11881 atccactccg ggattgggcg gtaataacgc ccttcgctac gccagttgcc aaatgcagaa
    11941 atagcggcaa aagcggcgac ccaggttttg atttcatgtg tcgactttcc ggcaatggcg
    12001 gaaagctctt cgttactgac ggcatccagt tcctgtatgc gtccctgctc cagcaaagtc
    12061 atgaactggt tatcccaaat cgggttgagc ggatgcagag ttctctgatc ctcaacaaac
    12121 ttctcagcgg cgctaatcac ccgttgctga cgcaattcgc gctcactggc gggtaaatct
    12181 ttcccgctcc ccaacagacg gtcgcgcata tgggcatcgg ctttcgccag ttcgggcacc
    12241 ggcggctgat gggaaagccc accggaaccc aggaacagca cgcgtttatt gagagtgctg
    12301 gtgaaacgtc caatggcttc acccaacatg cgggtacgct ggaaaccggg cagcggcgtg
    12361 gcgacaccgt tgatgaacac aggcagaact ggcaccttat ccagcccgcc gagcaggaac
    12421 tccagtggct gggcgaaccc gtggtccacc tgcatacagt aagaaacggc aagatcgatc
    12481 ccgctcttca tgacggcatg cgcacaggcc tccgccagct ccacaggcac tggcagctct
    12541 cctgccgcac tgccgaaatc accaattgcc gtcgctccaa cgcctaaaca gaacggtggc
    12601 atcacgtcat agaaaaagcc gttgtagtga tctggcgcaa acagcaccac cagttcaggg
    12661 gagaaagccg caatacgctc gcgggcgctg gcaatcacgc cattgacctc atcgagcacc
    12721 tcttgcgccg ggtcgacata ccccaccagc ggcgagtggg aaagacagtg aagataagcg
    12781 tgcatatcag gctacctttt cgacagaaac gtcggcatca gggcgggtca gcgtcatcac
    12841 cgacgccagt ttattcaggg tcttgcccag ggtttgcgga atggcggtgg cggcaacaaa
    12901 gcgatccggg cgcatcacca ccagcgaagc attgtgttgc gcgaaccagc tacgcagacg
    12961 accttgcgta tcgcccacgc gtagcacgcc gtcgtggtta tcctgtgcgg tatgaatttg
    13021 cacttccggc accacctgaa tgaagcgtgt gcccaacgcg cgccactgct ggatttgctc
    13081 gtcgctcatc ccccacagtg gattgcatcc ccagccaatt accgcgaagt tcgcgccaat
    13141 cgcgttatcg agcagcgtca cgtcaccgtt ttccagcgtg actttcggct gaataaacat
    13201 cttgccgacc ggagagtgct tcgcttcgcc ctcacgcacc agcgcaccgc cgtaatattg
    13261 cggcatcggc ttgaagcgca tttcgaggaa atagcgtttt actggcggca gataattcaa
    13321 cagccaggaa acgccgtcac gtaacgtacc ctgccagcgt ttcggcggag ccagcacgtt
    13381 gcccgccgtc acggacaggt caatcatcgc tttggcgtga tcgcgacgtt cttgttgata
    13441 ggtatcgagc agcgcatcgc gggctttccc ctggataacc aacgccagtt tccaggcgag
    13501 gttaaaggcg tcgcgcatac cactgttata gccctgcccc tgccacaccg gcatgatgtg
    13561 cgcggcatcg cccgccagca gtacgcgatc aatacggaaa cgttgcgcca gtcgcgcgtt
    13621 atgggtgtag acacgctggc gaatcaattc aacattgtcc ggattaggca gcactttgct
    13681 taacagcttg cgcatatttt gcggctcacg cagctgctct tcggtttctc ccggcatcac
    13741 cataaattca aagcgacgta ccgcatgagg cagcgcggca gaaacatacg ggcgcaccgg
    13801 atcgcaacac aaatagatat gcggcgtact taacggatcg ttggcgatat ctaccacaat
    13861 ccactgattt ggcgcagttt taccttcaaa cggcacattc agagtgcgac ggacaaaact
    13921 tgctccaccg tcacaggcta ccagccactg ggctttgacc gtttcccgct gcccttctgc
    13981 cgttttcagg tgcaaggtca cttcgtcatt ttgctggctg aaggcctcca gctcgcggga
    14041 aaacaagcag cgcacattcg gaaaacgcga caacccttcc agcatcaccg catcgacctg
    14101 aggctgaata aaggcgttac ggcgcggcca gccaaattca tcggtcattg gctgaatatc
    14161 agcaaaacag cggcctttcg gggtgagaaa acgcatcgcg tgccacggcg tagtgtgcgg
    14221 cagaacatca tcgaccaggc cgaccgactg catggtgcgc agcgcctcgt catcaatacc
    14281 aatcgcacgc gggtagtcga tcaacttatc gagtttttcc accaccagca cgtcaatgcc
    14341 catctggccg agatagttcg ccatcatcag cccgaccgga ccggcaccag cgatcgccac
    14401 ctgaacgcta tggttaacag caggctggat gtcagggtgt tgtattgcca tttcagtacc
    14461 tcacgactcg gacaaaatgc cgttgcgcgc acagtacggc gcaacttatt ttgttaaaaa
    14521 catgtaaatg attttttatt gtgcgctcag tataggaagg gtgttttcgg ctacaatcaa
    14581 aacatgcccg aatgtgcacc aggtgcacaa ctttgtttta actatagaaa tgtcaattaa
    14641 tatgcagaac aatgagcaga cggaatacaa aaccgtgcgc ggcttaaccc gcggtctaat
    14701 gttattaaat atgttaaata aacttgatgg cggtgccagc gtcgggctgc tggcggaact
    14761 cagcggcctg catcgcacca ctgtgcggcg actgctggag acgctgcagg aagagggata
    14821 tgtccgccgt agcccctccg atgatagttt tcgtctgacc atcaaagtgc ggcaattaag
    14881 cgaaggattt cgtgacgaac agtggatttc tgcactggcg gccccactgc tgggcgatct
    14941 gttgcgcgaa gtggtatggc cgacagatgt gtccacgctg gatgttgatg caatggtggt
    15001 acgcgaaacc actcaccgtt tcagccgctt atcctttcac cggccaatgg tcgggcgacg
    15061 tttgccgctt ctgaaaaccg cctctggcct gacctggctg gccttttgcc cggaacaaga
    15121 ccgcaaggaa ttaatcgaaa tgttagcctc ccgccccggt gatgactatc aactggcacg
    15181 ggaaccgtta aagctggaag ccattctggc gcgcgcgcgc aaagagggtt acggacagaa
    15241 ctaccgcggc tgggatcagg aggagaagat cgcctctatc gccgtaccgc tgcgcagtga
    15301 acaacgggtg attggctgtc tgaatctggt gtatatggcg agcgcaatga ccattgaaca
    15361 ggcagcggaa aagcatcttc cggcgctaca acgggtagca aaacagatcg aagaaggggt
    15421 tgaatcgcag gctattctgg tggccggacg gcgaagcggc gtgcatttac gttgacacca
    15481 tcgaatggcg caaaaccttt cgcggtatgg catgatagcg tccggaagag agtcaattca
    15541 gggtggtgaa tgtgaaacca gtaacgctat acgatgtcgc agagtatgcc ggtgtctctt
    15601 atcagaccgt ttcccgcgtg gtgaaccagg ccagccacgt ttctgcgaaa acgcgggaaa
    15661 aagtggaagc ggcgatggcg gagctgaatt acattcccaa ccgcgtggca caacaactgg
    15721 cgggcaaaca gtcgttgctg attggcgttg ccacctccag tctggccctg cacgcgccgt
    15781 cgcaaattgt cgcggcgatt aaatctcgcg ctgatcaact gggtgccagc gtggtggtgt
    15841 cgatggtaga acgaagcggc gtcgaagcct gtaaagcggc ggtgcacaat cttctcgcgc
    15901 aacgcgtcag tgggctgatc attaactatc cgctggatga ccaggatgcc actgctgtgg
    15961 aagcagcctg cgctaatgtt ccggcgttat ttcttgatgt ctctgaccag actcccatca
    16021 acagtattat tttctcccat gaagacggta cgcggctggg cgtggagcat ctggtcgcat
    16081 tgggtcacca gcaaatcgcg ctgttagcgg gcccattaag ttctgtctcg gcgcgtctgc
    16141 gtctggcggg ctggcataaa tatctcacac gcaatcaaat tcagccgata gcggaacggg
    16201 agggcgactg gagtgccatg tccggttttc aacaaaccat gcaaatgctg aatgagggca
    16261 tcgttcccac tgcgatgctg gttgccaacg atcagatggc gctgggcgca atgcgcgcca
    16321 ttaccgagtc cgggctgcgc gttggtgcgg atatctcggt agtgggatac gacgataccg
    16381 aagacagctc gtgttatatc ccgccgttaa ccaccatcaa acaggatttt cgcctgctgg
    16441 ggcaaaccag cgtggaccgc ttgctgcaac tctctcaggg ccaggcggtg aagggcaatc
    16501 agctgttgcc cgtctcactg gtgaaaagaa aaaccaccct ggcgcccaat acgcaaaccg
    16561 cctctccccg cgcgttggcc gattcattaa tgcagctggc acgacaggtt tcccgactgg
    16621 aaagcgggca gtgagcgcaa cgcaattaat gtgagttagc tcactcatta ggcaccccag
    16681 gctttacact ttatgcttcc ggctcgtatg ttgtgtgaaa ttgtgagcgg ataacaattt
    16741 tacacaggat acagctatga ctatgattac ggattcactg gtcgtcgtat tacaacgtcg
    16801 tgactgggaa aaccctggcg ttacccaact taatcgcctt gcagcacatc cccctttcgc
    16861 cagctggcgt aatagcgaag aggcccgcac cgatcgccct tcccaacagt tgcgcagcct
    16921 gaatggcgaa tggcgctttg cctggtttcc ggcaccagaa gcggtgccgg aaagctggct
    16981 ggagtgcgat cttcctgagg ccgatactgt cgtcgtcccc tcaaactggc agatgcacgg
    17041 ttacgatgcg cccatctaca ccaacgtgac ctatcccatt acggtcaatc cgccttttgt
    17101 tcccgcggag aatccgacgg gttgttactc gctcacattt aatattgatg aaagctggct
    17161 acaggaaggc cagacgcgaa ttatttttga tggtgttaac tcggcgtttc atctgtggtg
    17221 caacgggcgc tgggtcggtt acggccagga cagccgtttg ccgtctgaat ttgacctgag
    17281 cacattttta cgcgccggag aaaaccgcct cgcggtgatg gtgctgcgct ggagtgacgg
    17341 cagttatctg gaagatcagg atatgtggcg gatgagcggc attttccgtg acgtctcgtt
    17401 gctgcacaaa ccgagcacac aaatcagcga tttccatgtt gccactcact ttaatgatga
    17461 tttcagccgc gcggtactgg aagcagaagt tcagatgtat ggcgagctgc gcgatgagct
    17521 gcgggtgacg gtttctttgt ggcagggtga aacgcaggtc gccagcggca ccgcgccttt
    17581 cggcggtgaa attatcgatg agcgtggtgg ttatgccgat cgcgtcacac tacgtctgaa
    17641 cgtcgaaaac ccgaaactgt ggagcgccga aatcccgaat ctctatcgtg cggtggttga
    17701 actgcacacc gccgacggca cgctgattga agcagaagcc agcgatgtcg gtttccgcga
    17761 ggtgcggatt gaaaatggtc tgctgctgct gaacggcaag ccgttgctga ttcgcggcgt
    17821 taaccgtcac gagcatcatc ctctgcatgg tcaggtcatg gatgagcaga cgatggtgca
    17881 ggatatcctg ctgatgaagc agaacaactt taacgccgtg cgctgttcgc attatccgaa
    17941 ccatccgctg tggtacacgc tgtgcgaccg ctacggcctg tatgtggtag atgaagccaa
    18001 cattgaaacc cacggcatgg tgccaatgaa tcgtctgacc gatgatccgc gctggctacc
    18061 ggcgatgagc gaacgcgtaa cgcgaatggt gcagcgcgat cgtaatcacc cgagtgtgat
    18121 catctggtcg ctgggaaatg agtcaggcca cggcgctaat cacgacgcac tctatcgctg
    18181 gaacaaatct gtcgatccat cccgcccggt gcagtatgaa ggcggcggag ccgacaccac
    18241 ggccaccgat attatttgcc cgatgtacgc gcgcgtggat gaagaccagc ccttcccggc
    18301 tgtgccgaaa tggtccatca aaaaatggct ttcgctacct ggagagacgc gcccgctgat
    18361 cctttgcgaa tacgcccacg cgatgggtaa cagtcttggc ggcttcgcta aatactggca
    18421 ggcgtttcgt cagtatcccc gtttacaggg cggcttcgtc tgggactggg tggatcagtc
    18481 gctgattaaa tatgatgaaa acggcaaccc gtggtcggct tacggcggtg attttggcga
    18541 tacgccgaac gatcgccagt tctgtatgaa cggtctggtc tttgccgacc gcacgccgca
    18601 tccagcgctg acggaagcaa aacaccagca gcagtttttc cagttccgtt tatccgggca
    18661 aaccatcgaa gtgaccagcg aatacctgtt ccgtcatagc gataacgagc tcctgcactg
    18721 gatggtggcg ctggatggta agccgctggc aagcggtgaa gtgcctctgg atgtcgctcc
    18781 acaaggtaaa cagttgattg aactgcctga actaccgcag ccggagagcg ccgggcaact
    18841 ctggctcaca gtacgcgtag tgcaaccgaa cgcgaccgca tggtcagaag ccggacacat
    18901 cagcgcctgg cagcagtggc atctggcggc aaacctcagc gtgacactcc cctccgcgcc
    18961 ccacgccatc ccgcaactga ccaccagcga aacggatttt tgcatcgagc tggataataa
    19021 gcgttggcaa tttaaccgcc agtcaggctt tctttcacag atgtggattg gcgatgaaaa
    19081 acaactgctg accccgctgc gcgatcagtt catccgtgca ccgctggata acgacattgg
    19141 cgtaagtgaa gcgacccgta ttgacccgaa cgcctgggtc gaacgctgga aggcggcggg
    19201 ccattaccag gccgaagcgg cgttgttgca gtgcacggca gatacacttg ccgacgcggt
    19261 gctgattacc actgtccacg cgtggcagca tcaggggaaa accttattta tcagccggaa
    19321 aacctaccgg attgatggta gtggtcaaat ggcgattacc gttgatgttg aagtagcgag
    19381 cgatacaccg catccggcgc ggattggcct gacctgccag ctggcgcagg tagcagagcg
    19441 ggtaaactgg ctcggattag ggccgcaaga aaactatccc gaccgcctta ctgccgcctg
    19501 ttttgaccgc tgggatctgc cattgtcaga catgtatacc ccgtacgtct tcccgagcga
    19561 aaacggtctg cgctgcggga cgcgcgaatt gaattatggc tcacaccagt ggcgcggcga
    19621 cttccagttc aatatcagtc gctacagcca acaacaactg atggaaacca gccatcgcca
    19681 tctgctgcac gcggaagaag gcacatggct gaatatcgac ggtttccata tggggattgg
    19741 tggcgacgac tcctggagcc cgtcagtatc ggcggaattc cagctgagcg ccggtcgcta
    19801 ccattaccaa ttggtctggt gtcaaaaata ataataaccg ggcaggccat gtctgcccgt
    19861 atttcgcgta aggaaatcca ttatgtacta tttaaaaaac acaaactttt ggatgttcgg
    19921 tttattcttt ttcttttact tttttatcat gggagcctac ttcccgtttt tcccgatttg
    19981 gctacatgac atcaaccata tcagcaaaag tgatacgggt attatttttg ccgctatttc
    20041 tctgttctcg ctattattcc aaccgctgtt tggtctgctt tctgacaaac tcgggctgcg
    20101 caaatacctg ctgtggatta ttaccggcat gttagtgatg tttgcgccgt tctttatttt
    20161 tatcttcggg ccactgttac aatacaacat tttagtagga tcgattgttg gtggtattta
    20221 tctaggcttt tgttttaacg ccggtgcgcc agcagtagag gcatttattg agaaagtcag
    20281 ccgtcgcagt aatttcgaat ttggtcgcgc gcggatgttt ggctgtgttg gctgggcgct
    20341 gtgtgcctcg attgtcggca tcatgttcac catcaataat cagtttgttt tctggctggg
    20401 ttctggctgt gcactcatcc tcgccgtttt actctttttc gccaaaacgg atgcgccctc
    20461 ttccgccacg gttgccaatg cggtaggtgc caaccattcg gcatttagcc ttaagctggc
    20521 gctggaactg ttcagacagc caaaactgtg gtttttgtca ctgtatgtta ttggcgtttc
    20581 ctgcacctac gatgtttttg accaacagtt tgctaatttc tttacttcgt tctttgctac
    20641 cggtgaacag ggtacgcggg tatttggcta cgtaacgaca atgggcgaat tacttaacgc
    20701 ctcgattatg ttctttgcgc cactgatcat taatcgcatc ggtgggaaaa acgccctgct
    20761 gctggctggc actattatgt ctgtacgtat tattggctca tcgttcgcca cctcagcgct
    20821 ggaagtggtt attctgaaaa cgctgcatat gtttgaagta ccgttcctgc tggtgggctg
    20881 ctttaaatat attaccagcc agtttgaagt gcgtttttca gcgacgattt atctggtctg
    20941 tttctgcttc tttaagcaac tggcgatgat ttttatgtct gtactggcgg gtaatatgta
    21001 tgaaagcatc ggtttccagg gcgcttatct ggtgctgggt ctggtggcgc tgggcttcac
    21061 cttaatttcc gtgttcacgc ttagcggccc cggcccgctt tctctactgc gtcgtcaggt
    21121 gaatgaagtc gcttaagcaa tcaatgtcgg atgcggcgcg agcgccttat ccgaccaaca
    21181 tatcaggacg gaatgatcgc aatgaacatg tcgatgacag aaagaataaa agcaggcaag
    21241 ctatttaccg atatgtgcga aggcttaccg gaaaaaagac ttcgtgggaa aacgttaatg
    21301 tatgagttta atcactcgca tccatcagaa gttgaaaaaa gagaaagcct gattaaagaa
    21361 atgtttgcca cggtagggga aaacgcctgg atagaaccac ctgtctattt ctcttacggt
    21421 tccaacatcc atataggccg caatttttat gcaaatttca atttaaccat tgtcgacgac
    21481 tacacggtaa cgatcggtga taacgtattg attgcaccca atgttactct ttccgttacg
    21541 ggacaccctg tacaccatga attgagaaaa aacggtgaga tgtactcttt tccgataacg
    21601 attggcaata acgtctggat cggaagtcat gtggttatta atccaggcgt caccatcggg
    21661 gataattctg ttattggcgc gggtagtgtc gtcataaaag acattccacc aaacgtcgtg
    21721 gctgctggcg ttccttgccg ggttattcgc gaaataaacg accgggataa gcaatattat
    21781 ttcagagatt acaaagttga atcgtcagtt taaattataa aaattgcctg atacgcttcg
    21841 cttatcaggc ctacaaattc agtgatctac gtaggccgca tccggcgtga acaaagcgca
    21901 gaaacaagag tcgcatcatg cctctttgac ccacagctgc ggaaaacgtg ctggtgcaaa
    21961 acgcagggtt ataatcatca gcccaacgac gcacagcgca tgaaatgccc agtccatcag
    22021 gtaattgccg ctgatactac gcagcacgcc agaaaaccac ggggcaagcc cggcgatgat
    22081 aaaaccgatt ccctgcataa acgccaccag cttgccagca atagccggtt gcacagagtg
    22141 atcgagcgcc agcagcaaac agagcggaaa cgcgccgccc agacctaacc cacacaccat
    22201 cgcccacaat accggcaatt gcagcggcaa ccagataaag ccgcagaacc ccaccagttg
    22261 taacaccagc gccagcatta acagtttgcg ccgatcctga tggcgagcca tagcaggcat
    22321 cagcaaagct cctgcggctt gcccaagcgt catcaatgcc agtaaggaac cgctgtactg
    22381 cgcgctggca ccaatctcaa tatagaaagc gggtaaccag gcaatcaggc tggcgtaacc
    22441 gccgttaatc agaccgaagt aaacacccag cgtccacgcg cggggagtga ataccacgcg
    22501 aaccggagtg gttgttgtct tgtgggaaga ggcgacctcg cgggcgcttt gccaccacca
    22561 ggcaaagagc gcaacaacgg caggcagcgc ccaccaggcg agtgtttgat accaggattc
    22621 gctatgttga actaaccagg gcgttatggc ggcaccaagt ccaccgccgc ccatcagagc
    22681 cgcagaccac agccccatca ccagtggcgt gcgctgctga aaccgccgtt taatcaccga
    22741 aggcatcacc gcctgaatga tgccgatccc caccccacca agcagtgcgc tgctaagcag
    22801 cagcgcactt tgggggtaaa gctcacgcat caatgcaccg acggcaatca gcaacagact
    22861 gatggcgaca ctgcgacgtt cgctgacatg ctgatgaagc cagcttccgg ccagcgccag
    22921 cccgcccatg gtgaccaccg gcagagcggt caacagggca gccacgctaa agctcattcc
    22981 gctcgcctgg cgcaattgcg gtagcagtgg cccgacggag gtgagcagtg gtcgcatatt
    23041 aagaccaatc agcaccagaa ccagcagcat cgtgaacgtc ttttgatgat tgcgcatggc
    23101 tgtcagaacg gcttggtcgg cagatattta ccatctaagg taatgaccgc acgttcgcca
    23161 ccttccgggt ccgccacttt cttaacgtcg agtttgaagt taatcgcgct gataatgcca
    23221 tcgccaaact tctcatgaac caacgctttc agggttgtgc cgtacacctg caacatttca
    23281 tagaaacgat acatcgttgg gtcggttgga atacggtcat caatgcagcc acgcagtgga
    23341 atcatctgca acagtagaat ggcgtcttcg tcgagatcca gcttcgcccc gaccaggcgg
    23401 gcggcgtcgg caggaagcgc ttgctgcccc agcaaagccg cggttacgaa ggcttctgcc
    23461 agaccggtac cgtcggcaat ctcggcaaat gagagatctt ttttagcttt gctgagcaaa
    23521 atggcatcgg caagatcaag acgaatattg cggttaattt gtgactgaat catggtggat
    23581 ctcctgatgg tttaaaaata aggttacgct gcggtcggtt ggcgtagcgg tatggcacaa
    23641 acgcgaggat tagcggccag tggcacaaac tggcgggttg cgccgtcaaa agctgcgatg
    23701 ctgccgcttt caatgtcgta gacccagccg tgcagggcga tccgcccctc ttcgagcgcc
    23761 aggcgcaccg atggatgagt ttgcaaatta gccaactgag caatgacgtt ttcacgtacc
    23821 atcgccgcag cttttgacgg taaatcggaa tgcgggcgcg cctcattaac gacgcgggct
    23881 gaatcggcat aacgcagcca gtgggagacg gcaggcatat ggtccatgca ctgacagctg
    23941 gcaatggcgg tcatcgcgcc acagttggaa tgaccacaaa tcacaatgtc agatacccga
    24001 agcgcagcga cggcatactc caccgaagca gaaacgccac cgggttccgg cccgtaggaa
    24061 gggacgatat tgcccgcgtt gcgaataacg aacagatcgc caggctcacg ttgcgtcacc
    24121 agctcaggga ccagacggct gtcggagcag gagataaaaa gtgtgcgcgg gctttgctgt
    24181 gtcgccagct gtttaaacaa ggcttcccgc ttcggaaatg cctcgcgctg gaatttaagg
    24241 aatccatcaa taatctcttt caccgttaac ctctgtctgt ctctggaatg agaggcagac
    24301 tactcgccga ttgtcataag gtaaaagtct catttatgat gagttctatt ggatttactt
    24361 ataggttggc gaatgctctc tcgacatatc aattactttc ttgccgtggc tgaacatggc
    24421 agcttcaccc gtgccgccag tgcgttgcac gtctcccagc ctgcgctttc ccagcagatt
    24481 cgccagttag aggagagttt gggcgtgccg ctgtttgacc gtagcgggcg aacgattcgt
    24541 ctcaccgatg caggagaagt ctggcgacag tacgccagcc gggcgttaca tgaactggga
    24601 gcgggtaaac gggcgattca tgatgttgcc gctctgacgc gaggatcgct gcgtatcgcc
    24661 gtcaccccca cctttacgag ctactttatc ggccccttaa tggcggattt ctatgcgcgc
    24721 taccccggca tcacgctcca gctacaggaa atgtcgcagg agaaaatcga agatctgctt
    24781 tgtcgcgacg agctggacgt tgggattgcc ttcgcgcctg tgcattcgcc ggagctggag
    24841 gcaattcctt tactgacaga aagtttagcg ttggtggtgg cgaaacatca tccgctggct
    24901 gcctgtgaac aggtggcgtt gagtcgcttg catgatgaaa aactggtcct gctcagcgcg
    24961 gaatttgcca ccagagagca aattgaccac tactgcgaga aagcggggct acatccacag
    25021 gtggtcattg aggcgaactc aattagcgcg gttctggagc tgattcgccg cacttccctt
    25081 tccacattgt taccagcagc gattgccaca caacatgacg ggcttaaagc gatttctctt
    25141 gccccgccac tactggagag aacggcggtt ttgttgcggc ggaaaaatag ctggcagact
    25201 gccgctgcga aggcattttt gcacatggcg ttggaggaat gtgcggatgt tggcgagaat
    25261 gaatcacggt agccactgac acaggtcagt ggatcttcaa cacagaggaa attaccgttt
    25321 gtaatcgatg gcttctggct gctccagata tacggtggtt tgtgccggtt gtgtactggc
    25381 aatcaccttg ccgccacgta ccgaataacg taccggaacc tgacggcgca gcgcatcaaa
    25441 tccattttca gccggcagga taatcaggtt tgcgctgttt ccggcggcaa tgccgtaatc
    25501 ctgcaaattc aatgttctgg cactgtggtg ggtgattaaa ttcaggccat cgttaatctg
    25561 cccgtagccc atcaactggc aaacatgcag ccccatatgc agcacttgca gcatattcgc
    25621 cgttcccagc ggataccacg gatcgaagac atcatcgtga ccaaagcaga cgttaatgcc
    25681 ggactccagc atctctttaa cgcgcgtgat gccgcgacgt tttggatacg tatcgaaacg
    25741 tccttgcaga tgaatattga ccagcgggtt ggcgacaaag ttaataccgg acattttcag
    25801 caagcggaac aggcgtgagg tatacgcccc gttataggag tgcattgccg tggtgtggct
    25861 ggcggtgact cgcgcgccca tgccttcacg gtgcgccagg gcagcaacgg tttcgacaaa
    25921 gcgcgactgc tcgtcatcga tctcatcaca gtgaacgtcg atgagacggt cgtatttttg
    25981 cgccagggcg aaggttttat gcagcgactc cacgccgtat tcacgggtaa attcaaaatg
    26041 cggaatcgcc cccactacat ctgcccctaa gcgtaacgcc tcttccagca acgcttcacc
    26101 gttgggatac gacaaaatcc cttcctgagg gaaggcgaca atttgcagat caatccacgg
    26161 cgcgacttcc tgcttcactt ccagcattgc tttcagcgca gttagcgttg catccgaaac
    26221 atcgacatgg gtacgcacat gctgaatgcc gttggcaatc tgccatttca gcgtttgcca
    26281 ggcgcgttgt ttcacatcgt catgggttaa taacgctttg cgctcggccc agcgttcaat
    26341 gccttcaaac agcgtgccgg actgattcca gttcggttgt ccggcggttt gcgtggtgtc
    26401 caggtgaata tgcggctcca caaacggcgg tataactaaa ccttgttcgg catccaggct
    26461 gttttcagtt atgggcatca cgccggattg cgcatcaatg gcgctgattt ttccgtcctg
    26521 cagatgaatc tgccacagcc cctctttgcc tggtaaccgg gcgttaataa ttgtttgtaa
    26581 agcgttattc gacactgtta acctccacat gcgtcattgc tgctgtcgtt ttacgattca
    26641 aaatcgggtt aaggatcaga tagctcagcg cgccacctaa taccgcgttg accggaacaa
    26701 ttcccggtaa ccagtggcct gcggcaatcc ccagcgcgac cgccagaatc gccacccaat
    26761 tgacactcat catacgcgtg gtcgcaaagt gctcatagcg gcgacggttc atcagatagt
    26821 cggcgatgat cacgccccct actggaggaa tagctgccga aaggaaggtc aaccagtcga
    26881 caaaattgtt atacagccat aatgcgcaga ccgtaccgat aataccgttg attaccgaaa
    26941 gggttttgct cgacataccg gtaatgttgg cgaaacctaa acccgacgca tagagtgcgt
    27001 tatcgttggt ggtccagata ttcagcccca gcaccacaat cgcaggcagc agcaggccct
    27061 gagcaatcat cacatcagag atatccgcca tgcccagtgc cgcagcgccc gctgcaccga
    27121 aaataaacat caacgagttg ccgaggaaaa aggccaccat cgccaccagc accgccagtt
    27181 tggcattgcg accaaaccgg acaaagtcag cggtgagcgt acccgcactg ataaatgacc
    27241 ccacaaccag cgccagcgcg acattgaaat ctaacggttg tgcgggaacg accgctttta
    27301 atgcgtccag gccgcccatg ccgttaacag ccagccacac ggaataaccg cccaggcagg
    27361 cgatagccgg aaccgcaatc accgaaagaa ccgtcagcgc cgaaatgcca aaaaagacgg
    27421 tgacggtcat cagtaaaccg gaaacggcaa tcagcaaatt aatatccagc ccggttgcct
    27481 tacccaccgg aatggcaaac atcgccacac cgacgccaaa ccagccaacc tgagttccgc
    27541 ccagtagcag tgaaggcagc catgagcctt taacaccaaa cgagaagcga gcaagaagat
    27601 gagtggtcag gccggttttt gcgccaatgt aaccgagaaa tgaagtgtaa ataccgagga
    27661 gaagattacc gatgagaact gcgaggaaga aatcatgata gctaagaccg gttccgagag
    27721 tgccgccggt ccacatactg gcggaaaaga aggttaatcc cagcatgacg aacgtcaatg
    27781 ccaatacccc tttccgcgcc gactgcggga ctggcccctg gctaaagttg ttatcttgcg
    27841 acacgaaatt cccccttttt gctgtttgaa acccaaaaaa tccgccgcat tctattcatc
    27901 tgaagataaa aagcaatcgt tttcgtgggg aaatatattt tttatatgaa tgagtgcaaa
    27961 aaggtggggg aaaaattatc ggtgtaaaaa cagtgggtag tgggtaggcc tgataagacg
    28021 cgtcagcgtc gcatcaggca tcggcgcatg gtgtcggatg cgccacgcga cgcatccgac
    28081 aataccttac tcttccatcg cctggcggat ctgatccaat gacgcaggat catcaatggt
    28141 cgtcagatcc ccaggatcgc gtccttcgca aattgcctgg atcgtgcggc gcagcatttt
    28201 tccggatcgc gttttcggca attgcgagac aaaccagacg tgcgccgggc gaccaaagtt
    28261 gccaatctgg ctgtccacca gcgccataat cgccttctct tgcgaatgcg ccacatcacg
    28321 atcttccaga ctatcgctct ctttcggaat gacaaacgcc accgccacct gccctttcag
    28381 cgcatctttc accccaacca ccgccacttc ggcaacgccc ggatggctgg agatactctc
    28441 ttcaatctcg cgcgtgccca gacgatgccc ggcaacgtta attacatcgt cagtgcgccc
    28501 gagaataaag tgataaccgt cagcgtcacg gatgccccag tcaaaggtgg cgtacaccgg
    28561 gcgggaaaac agcgaccagt aagtcttcac aaagcggtcg tcgtcgcccc agatggtctg
    28621 aatacagccc ggcggcagcg gcccttccac caccagcatc cctttctcgt tgacgccaca
    28681 cggttcgccg gtgacttcat taagcaactg cacgttatag ccatacatcg gcacgccggg
    28741 gcttcccaga cgcgtcggcc tgtcgtccag accgcgagca atcgccataa tcggccagcc
    28801 ggattcggtc tgccagtagt tgtcgatgac cggcacatcc agcgtattgc tcacccaact
    28861 ggcggtcggc tcgtccagcg gttctccagc cagatagagc acttccagcg acgagagatc
    28921 gtgtttgcga atttcagcgg tagggaattt tttcagcacg cgaatggcgg tcggcgctga
    28981 gaacatccgg ctaacctgat atttctcgac gattttccac cacacgccgc agtccggcca
    29041 ggtcggcaat ccttcgtaaa cgatagtcgc catccccgcc agcagcggcg cgtaaacgat
    29101 atacgaatgc cccaccaccc agccgatatc cgatgcgcaa aagaacacgc tgcccgcttt
    29161 gccgccaaaa atggtgtcca tcgaggtcgc cagcgccacc gcatatccgc cgacgtcacg
    29221 ctgcacgcct ttaggtttgc cggtcgtgcc ggaagtgtag agaatgcagg aggtttcgtt
    29281 ggattccagc cacgccaccg gtacccgcgc gccgatgtgt tgatggcgca acgacgcgaa
    29341 atcgacatcc cgcccgctga cgcgcgccat tttcgccagc ccgcgatcca ccagcaaaac
    29401 atggcgtggc tggtgctgcg cctgacttat cgcatcgtcg agcaattttt tatagggaat
    29461 gattttgcca ccgcgcgctc cggcatcagc cgagacaatc agcaccggtt tagcgtcatc
    29521 aattcgcgcc gccacgctgt gcgaggcaaa accaccaaat accaccgaat gaatagcacc
    29581 aatgcgcgcg caggccagca gagtaatatg cgcttcggca atcatcggca tatacaccag
    29641 cacccgatcg ccgcgctgca cgcccagtga gcgcaacatt gaggccaccg cgttcacttc
    29701 gtcatgcagc tggcgaaagg taaaggtgcg ctcttcttct gtttccgaag agacggcaat
    29761 caatgccagt gcctctggct gtttctccag ccagcggtcg atagcgttgt ggcacaaatt
    29821 ggttcggcct tcacaaaacc aacgggcaaa cggcggattg ctgtggtcga gcgtttgcgt
    29881 aaagggcgtc tgccagtcaa tacgccgggc ctgctcggcc cagaactgct ccggttcgtt
    29941 aatcgaacgc tgataaaatt cgctaaaaga cataatgctc tcctgttgaa cttacgcctt
    30001 accgccgttt acttaaatga cgtacaggtc gagatactca ttgaccggca tctgttccag
    30061 gcgagttctg tcgagagaaa cctccagaat gcgctgctgt tggcgagtcg ggaactggcg
    30121 cgcgagattg attttgaatt tatcgaccag tttcggaata ccatcctgac ggcggcgagc
    30181 atgaccaatg gggtactcca ccaccacttc ttcaaatcgt gtgccgtcgg tgaactcaag
    30241 ggtaatggca ttggcgatgg cgcgtttttc cgggtcgtgg tagtcagcgg taaatgccgg
    30301 atcttcaaag caattgatct tctcgcgcag ggcgtcgatg cgtttatctt gcgcaacgtt
    30361 gtcctcgtaa tctgccgccg ttaagcgccc gaataacagc gggatcgcca ccatgtactg
    30421 aatgcagtgg tcgcggtcag ccgggttatt gagcggcccc tttttgtcga tgatgcgaat
    30481 acaggcttcg tgggtgcgaa tggtcacttt ttcgatatcc gccgccgtct tgcctgctgc
    30541 ctgcatctgt tcatagagcg tcatcgccgc ttcaactgcc gtctgggagt ggaactccgc
    30601 cgggaaggag attttgaaca gcacattctc catgacgtaa gaaccgtacg gacgctggaa
    30661 gcggaacgat tcacctttaa aggagacgtc gtagaagccc cataccggcg cagtcagggc
    30721 tgacgggtaa cccatttcgc ccgttttcgc catcagtgcc agacgtaccg cgcgggaagt
    30781 ggcatcgccc gccgcccagg atttacgcgt gccggtgttc ggcgcatggc gataggtgcg
    30841 cagcgactga ccgtccaccc acgccagcga aacggcgttg agaatttcct cgcgggtcag
    30901 gccgagcatt tcggcgacca cggcggtgga agccactttc actaacagaa cgtggtcgag
    30961 gccgacgcgg ttaaaggagt tttccagcgc gatgcagccc tgaatttcat gggctttgat
    31021 cattgcggtc agcacctgtt tcatggtcaa cggcgctttg ccgctggcga ccgcgttgcg
    31081 cgaaagccag tccgccgttg ccagaatgcc gccgaggttg tcggaaggat ggccccactc
    31141 cgccgccagc caggtatcgt tgaaatcgag ccagcggatc atcgcgccga tgttaaatgc
    31201 cgcctggacg gggtcgagct ggaactgagt tccggggacg cgcacgccgt tgggtacgac
    31261 ggtgccggga acaattggcc ccagcagttt tttacaggcc gggtattcga gagcttccag
    31321 accgcagccg agcgtgtcga gcaggcagta atgtgcggtg tcgtaggcca ctttagagct
    31381 gatttcgtag ttcatgacgt aatcgacgat atcaacgatt tcacgatcaa attccgggcg
    31441 gatgttgttg atttgagctg acattgggta cgtttcctta ttgttattcg tagaggttta
    31501 ctggcgctta tccagcgcga caaacgggcg gtcttccggt ccaacataat tggcggaagg
    31561 acggataatt ttgttgtcct gacgttgttc gataatgtgc gccgcccagc cggtgacgcg
    31621 ggcgataaca aacagtggtg tgaacatctc ggtgggaacg cccatcatgt tgtaggaaac
    31681 agcagagaac cagtcgagat tggggaacat ctttttgctc tcccacatca ccgtttccag
    31741 gcgatcggcg atgttgtaca tcttcagcga gccgccttcc tgcgagagct gcttcgccac
    31801 acgtttaatc acctggtggc gcgggtcagc gatggtgtaa accggatgac caaaaccaat
    31861 gaccacttct ttgttttcca cgcgcttgcg gatatctgct tcggcttcgt ccggcgtttc
    31921 gtagcgttgc tggatctcca gcgacacttc attcgccccg ccgtgttttg gcccgcgcag
    31981 tgcgccaatc gcgccaataa tcgcggaata catatcagag ccggtgcccg caatcacccg
    32041 actggtaaag gtggaggcgt taaactcgtg ttcggcgtac agcaccagcg agatatgcat
    32101 cgccttttcc cagctttgcg atggcttttc gccgtgcagc agatgcagga agtgaccgcc
    32161 gatggagtcg tcatcggttt ccggctggat gcgttcgccg ttgtgactgt agtgatacca
    32221 ataaaggaga atcgagctaa gtgatgccag cagtttgtcg gcaatatccc gcgcgccaga
    32281 gacagtgtgc ccctcttttt ctggcagtgt gcagccgagc gcggaaacgc cggtgcgcat
    32341 gacatccatc gggtgcgacg ccgccggtaa ggcttccagc acggtacgca cattagctgg
    32401 taaaccacgc agggctttca gtttcgtttt gtaagcggcg agttcgtcac gggtcggcag
    32461 tttgccgtgg atcagcaggt gcgccacttc ttcaaattcg caatgttccg ccagatcaag
    32521 aatatcgtag ccacggtaat gcaggtcatt gccactttta cccacggtgc agagcgccgt
    32581 attgcccgcc ggaacgccag aaagtgctac cgattttttc ggtttaatga catgggtact
    32641 gttttgcagg atcgttgtgt cgctcatatt gtcctcgtca tttgtagggt cgagatattt
    32701 ttcgttgtgt tttatttcac ctggctacgg gcaaacaggt cgtcgagctt ctcttcgtac
    32761 tggtagtagt tgatgctttc gtacagctcg ttgcgggttt gcatggtatc gatgacgctt
    32821 ttctgcgtgc cttcctgacg caggacgttg tagacatgtt cagcggcgcg gttcatggcg
    32881 cggaacgctg aaagcgggta cagcgccatt gcgacatggg cgctgcgtaa ttcgtcggtg
    32941 gtaaacagcg gtgttgcgcc aaattcggta atgttggcga ggattggcac ctgcaccgca
    33001 tcggcaaact ggcggtacat ggcgagttcg gtaatcgcct ccgggaacaa catctcggca
    33061 cccgcttcaa cataggcctg cgcacgctcg atcgccgcat ccagcccctc taccgccaga
    33121 gcatcggtgc gcgccatgat cacaaaatca ggatcggttt tcgcatccac cgccgcgcgg
    33181 atccgatcca ccatctcttc tttcgagacg atcgctttat tcggacgatg accgcagcgt
    33241 ttcgcaccaa cctgatcttc aatatgcaat cctgccgcac cggctttaat catcgatttc
    33301 acggtgcgcg ccacgttaaa ggccgaagaa ccaaaaccga tatccgcatc caccagcagc
    33361 ggcagcgaac aaacgtcggt gatacggcga atgtcggtca gcacatcatc aagggtagaa
    33421 ataccgagat cgggcagccc cagcgaacct gccgccacgc caccgccaga aagataaatt
    33481 gcctgatatc cggcacgctg cgccaacagc gcatgattag cgttgatggt gccaacaatc
    33541 tgcaatggat tttctttagt cagtgcagcg cgaaacgctt tacctggaga gtgtagagac
    33601 atagcccatc ctttgttatc aacttgttat ttgcgttgat aaagacaaag caaggggtgt
    33661 gccacaattg ccttaataaa attaaatgtt taatttcaat ttgttagaga taaagtcatg
    33721 aactaatccg caaatatgcg tttcagttaa cgtttcaggc aatgtttcac cgcgtttcat
    33781 tgcaacaatt atgaaacaag actaaaccca atattcggtt tcttaacttt gcggtgcgct
    33841 atggcacatc caccacggct taatgacgac aaaccggtta tctggacggt atctgtaacg
    33901 cgcctgttcg agctgtttcg cgatatcagc ctcgagtttg atcacctggc gaacattacc
    33961 cctattcagc ttggctttga aaaagcagtg acctacatcc gcaagaaact ggcaaacgaa
    34021 cgctgtgacg ccatcatcgc ggctggctct aacggcgcgt acctgaaaag ccgcctgtca
    34081 gtgccagtta ttttgattaa accgagcggc tacgatgtgt tacaggcact ggcaaaagcc
    34141 ggaaaactca cctcttctat cggcgttgtc acctatcagg aaaccattcc agcgctggtg
    34201 gcgtttcaaa aaacctttaa tttgcgcctc gatcaacgta gctacattac cgaagaagac
    34261 gcacgcgggc agattaacga gctaaaagct aacggcaccg aagcggtggt cggcgcgggg
    34321 ctgattaccg atctggcaga agaagccgga atgaccggaa tttttatcta ttccgccgcc
    34381 accgtgcgcc aggcgttcag cgatgcgctg gatatgacgc gcatgtcgtt acgccataac
    34441 actcacgatg ccacccgcaa cgccctgaga actcgttacg tgctgggcga tatgctcggt
    34501 caatcaccac agatggaaca agtacggcag actattttgc tgtatgcccg ctccagtgca
    34561 gcggtgttga ttgaggggga aacggggacg ggcaaagagc tggcggccca ggcgattcat
    34621 cgggaatatt ttgcccgcca cgatgcgcga cagggcaaaa agtcgcatcc gtttgttgca
    34681 gtcaactgcg gggcgattgc cgaatcgctg ctggaagcag aactgtttgg ctatgaggaa
    34741 ggggcgttta ccggctcgcg acgcggcggt cgcgccgggc tgtttgaaat cgcccacgga
    34801 ggtacgctgt ttctcgatga gattggcgaa atgccgctgc cgttgcagac ccggctgctg
    34861 cgggtgctgg aagaaaaaga ggtcacccgc gtcggcgggc atcagcctgt tccggtggat
    34921 gtgcgggtca ttagcgccac tcactgcaat ctggaagaag atatgcggca agggcagttt
    34981 cgccgtgacc tgttttatcg gctgagtatt ttgcgtctgc aattgccacc actgcgcgag
    35041 cgggtggcgg atattctgcc actggcggaa agctttttga aagtgtctct ggcggcgctc
    35101 tccgccccgt tttctgccgc attacgccag ggattacagg caagcgaaac cgtgctggtg
    35161 cactacgact ggccgggcaa tattcgtgaa ctgcgcaata tgatggagcg actggcgcta
    35221 tttttaagtg tggaaccgac gccggattta acgccgcaat ttttgcagct gctactgccg
    35281 gaactggcgc gcgagtcggc gaaaactccc gctccacgct tactgacacc acaacaggca
    35341 ctggagaaat ttaatggcga taaaacagca gcggcgaatt atttaggcat cagccggacg
    35401 acgttctggc ggcggctgaa aagctgaact gccgaatgca gcgcgaacgc tttatccggc
    35461 ataaatttca atagatgatc accgataaac ttacgcatcg ggcatgttta catagggttc
    35521 agaattactt cttcttataa atatttgccg tgccgtggat cttattgtca gtttgaccgg
    35581 aggtcagtac caacacatca gccccttttt catccgcttt tttgatcaaa tcttctttcg
    35641 cgtctgcagt cgacatttca ttgctggttg aaatatcacc tattttttca tactgcgatt
    35701 caactttttc aaattccgct ttggtcatca attcagcggc atagacattg gtaacggcta
    35761 acgctaacgc accgactaac attttagaga ttattttcat attacggctc cagagttgtt
    35821 atcacactat cacccaccca cattattggg ttgattaata attagttcag tcagggcata
    35881 aacgccagta accggaaata agacactttg tgatctctct cgcacccgat tatttttggt
    35941 agaaatatga tgaagttact tcacttattt atggatgaaa tcactatgga tcctttgcac
    36001 gccgtttacc tgaccgtagg actgttcgtg attacttttt ttaatccggg agccaatctc
    36061 tttgtggtag tacaaaccag cctggcttcc ggtcgacgcg caggggtgct gaccgggctg
    36121 ggcgtggcgc tgggcgatgc attttattcc gggttgggtt tgtttggtct tgcaacgcta
    36181 attacgcagt gtgaggagat tttttcgctt atcagaatcg tcggcggcgc ttatctctta
    36241 tggtttgcgt ggtgcagcat gcgccgccag tcaacaccgc aaatgagcac actacaacaa
    36301 ccgattagcg ccccctggta tgtctttttt cgccgtggat taattaccga tctctctaac
    36361 ccacaaaccg ttttattttt tattagtatt ttctcagtaa cattaaatgc cgaaacacca
    36421 acatgggcac gtttaatggc ctgggcgggg attgtgctcg catcagttat ctggcgagtc
    36481 tttcttagtc aggcgttttc tttgcccgct gtgcgtcgtg cttatgggcg tatgcaacgc
    36541 gttgccagtc gggttattgg tgcaattatt ggtgtattcg cgctacgcct gatttacgaa
    36601 ggggtgacgc agcggtgagc agataattta ctctctacgt aatcaacctg atttgccgaa
    36661 tcccggccat cggcgatgat agcccccgta atgcgtggtc cttatttccg ataagtttac
    36721 ttgagtcttt agcttcccat ttcagcccac tctcccctgt gtgggctttt ttcattggtc
    36781 tgacccgtcc tgaatagcca aacaatggca atgttccact ttgcagggat gataataagg
    36841 ggatctgatt cagaagagtt ttgaaaagtt ggaccgccat cgaggcctcg aaccccgtac
    36901 catacaacaa tcctggttgt cgtctgctct tcctgatgag ctaatggcgg tttttgatat
    36961 gagccttaca gcatattttc tgtcaggctt gagtgcgatg cgtaagatac agaaaagacc
    37021 ccacacaaac atgatggaat tatgattttt ttcatatgaa tgtcaaccca cacattcaca
    37081 aaacatctgc atgagatcat tttttataca ccgcatggct gcgaaaccac tactggtgct
    37141 tttttaagcg aagtgtcgcc gatcacaaca aaatatcggc gaaaaaagag atggaatgcc
    37201 agttggcata cagatataca gatgaaatga ttacctgcat tgcgattcac tctcaggtgg
    37261 aataacaact tgcaggtgga accctttctg aactaaagag tgtagcggat tttaacgtgc
    37321 ttatttacag gataatatct gtcacctaat tcctggactc tattagatat ccattgattt
    37381 aatcgcgcat catctctgta tgtttttacg tccagaacag agagcaataa catcaccagt
    37441 gattcaggaa aaacagggta gatatttttt aagtgtaata ataatccatg cgcaagcgcc
    37501 tgcttaatgg gcgcgtctgt ctccggaata gacgacattt cgcgaagcca tttttccaca
    37561 tgcatacact ctttcccttt agggaaaatt ctcagcaaag gcatatggtg ttcaagaaga
    37621 atacatttgc aatctgttcg cactgaatcg ataaactgca ctaatttctt aagcccggta
    37681 aagcgtccag cctgcacgtt tgctttaata tcaagaaacg catcatcctg gtcatatacc
    37741 caaactgtcc ctttttgatt ttcaagtatg cgaaaaacaa acttaaccgg gtgatcaggg
    37801 taatccatcc agtcataaaa tccagggaaa tcattaaact gcacatttat ggtgagtgcg
    37861 ttatcgtctg accactcaca gtctcgtacg gcagccatga gatgaatgag tttgtcgtca
    37921 tcgactaaat catcacgaca atcataagga taatcataat attgtttaat caaaaccttg
    37981 aatatatcga cacaggaaac cagggagctt ttgatatcct ctggtaactg attgttttta
    38041 accgtattaa gtatgctttg ttgcgtatat ggcatcaaat tattgtgcgg agcttttaat
    38101 gatatcatcg cgatctctct taaataaaaa taaacgtcgc agataataaa gctctgatta
    38161 aaccaggcac tatcagaaat cgctcataac taacgtgtga agtattgtgt actggaggga
    38221 gttaatttaa taatttgaat ttacgttata ggttttactg ctactttgat attatttcgc
    38281 tctccttaac taaaaagtta agtggagagc gaagttaata tgttaaacca cagcgtattt
    38341 attaattttt tcagtctgtt agtgtgcgat tatcgataac aaaacgatat ttcacatcac
    38401 cgcgcagcat tcgctcatag gcttcattaa tttgatcggc ccgaatcatc tctatatcag
    38461 ccacaatgcc atgttcggcg caaaaatcga gcatctcctg agtttctgga atgccgccaa
    38521 tcatagaacc ggctatcgca cggcgtttca tgatcaggtt gaaaacttcc ggcgatttat
    38581 gcggtgtcgc aggcgcacca accagcgtca tggtgccatc acgcttcagc aaggtggtaa
    38641 aatcgtcgag attatgtggc gcagctactg tattcaaaat gaaatcgaaa ctcttcagat
    38701 gagccgccat ctcatcggca ttgcgtgagt taacaacttc atcggccccc agggcttttg
    38761 ccgcttcgcg ttttgcctca gaagtggtaa atgccaccac atgtgccccc atcgcgtggg
    38821 ccagcttaat ccccatatgt cccagaccgc cgatgccgac cacgcccact tttttacccg
    38881 gcccggcctg ccagtgacgt agcggcgaat acgtggtgat ccctgcacac aacaaaggag
    38941 ccaccgccgc cagctgctct tgcgggtgac gaatacgcag aacatatcgc tcatgaacga
    39001 cgatctgttg tgagtagccg cccagagtat ggcccggttc gtccggcgtc ggcgagttat
    39061 aggtgccggt catgtgatca cagtagtttt ccaacccgtc ttcacactct tcgcaatgtt
    39121 tacaactgtc gacaatgcag ccgacaccga ccagatcgcc cggcgcatat ttttctacct
    39181 gatcaccaac ggctaccaca cgccccacaa tttcatgacc cggcacgcag gggtaaaccg
    39241 tccccgccca ctcggaacgg acctggtgga gatcggaatg gcaaacgcca cagtaagcga
    39301 tttcgatttt gacatcattc ggtcccggtt cacgccgggt gatatccatc ggttcaagtg
    39361 gttgtttagc ggaatatgca ccaacagctt tgatcttcat tgtgtttact cctgattagc
    39421 tatgtgtatt tggcgacgcc tgatatgtca tcgcggcaaa acgcgtccat tgaatatagc
    39481 caatatttaa accacccgat ccagccccaa catgccgcga gcctgaatga aacagagcag
    39541 caacgttccc cataaggcca tcgtcaggta ggggcttata ccgagaatat tgaagccgct
    39601 ttcaataatt tgcagaagaa acagcgccag caccatacca attatccgcc cgctgccgcc
    39661 gtccggatta accccgccga gtactgccgc gaggattgac accagcaagt acgattcgcc
    39721 ataagaggcc ttagccgagt tgagtttcga catcatcaaa aatgccgcta ccgcacaaag
    39781 caaggcggaa atgacataaa cccaaatcag cacccgacga gtgttaatgc cggagtaaag
    39841 tgttgctcgt tcgttagacc caatcaggta aatggcttta ccgagcggcg ttttctccag
    39901 caatatccat agccccagtg ccactgcggc aaacaaccac atcggtagcg gaataccgaa
    39961 ccattgcgca tgattcaacc acagcaccca tgagggataa ttggcaatgg cgctaccacc
    40021 tgtcaccaga atatttatcc ctttgagcaa cgtcatcatc ccaagcgttg caagaattgg
    40081 cgacactcga ataccagcaa tcaatacgcc gttacataaa ccgattatca ccgccgcgcc
    40141 agcgcccgcc agtaacgtag cgacaaccgt agcaataccc ggtggatact gagtcgccac
    40201 ccacgccatc accagtgaac aggcgttagc agtggctata attgacaagt taatgccacc
    40261 gcaaagcatg gtcaccgcca tagccaacgc cagaatgccc agcacgggca tttgcgaagc
    40321 gacggactgg aaattactta tcgaccagaa aatctccggc atagtaatgc tgaacgcggc
    40381 aacagttagc gccagcaggc cgatcaagta aaactcaacg ttattacgcc acgatttttt
    40441 catagcagac tccggttctg atgctgactc cacgccgtgg cactaatgct ggcaacgatg
    40501 atgatgccgg tgatcaatgt ttgccagtaa gacgagactc ccaataaatt tagcccgttt
    40561 tgcatcactg ccaacaacac cacgccgagc aaagtaccgg ttaacgtgcc gcgcccgccg
    40621 agcaaactag tgccgccaag caccaccgca gccagtactg tcagctcata acccagaaga
    40681 gaatcggggg cgacagtcat caccgtccac gactgcacta cacccgcagc gccagacatc
    40741 aatcccatat agccatagac gaaaagttgc agtttcagca cgctaaagcc gatgcgactg
    40801 gctgattcgc ggttcccgcc aagggcataa attttgcgcc ctacactggt gaaattcatg
    40861 ataaacgctg ttagcagcac caccgtaatc atggcgatca gcggcagacc aaggccatag
    40921 tcatagccat cagcatcggt gtacttgaac aacataaccc cctgctcaaa ccacggcgga
    40981 aagtcgtaca gccacacacc tttactcaac cataacagca ggccatagaa aatattcagc
    41041 gtcgagatag tgatgatgat agaaggcacc cgtaggcgat taaccagtaa ggcgttaatt
    41101 aagccaagta aaatgccgat gcagcccgcc agtgcaaacg cgacagcgaa gttgccacca
    41161 attttttgca gcaacagcac catgccgtat tgcgcaatga tggtcattgc tggaaacgaa
    41221 atatcaattc caccggaaat caacaccaca aacaaaccac aggcgagaat agtcaacatg
    41281 gcatagttat tggcgagatc gtacaaatta ccgaatgtca gaaactcgtc gctgcgccag
    41341 gcaaggccaa caaacagcac cacaatcagt aatgccagcc agaattcatg gcgttttttc
    41401 agttcagcca tttaccacct ccgcaatcct ggcctgagaa ctgctgtcag gcaggaagct
    41461 atgggtgatc tgaccttttt gcattaccaa aatccggtgg ctttgatacc acgcttcttc
    41521 aatttcatcg cagatcatca ataccgcaat gccatgagcc gccagatcgc tgataatgcc
    41581 gtatattcct gctttgttgg cgatatcaac accgactgtc gggctatcga gaatcaacag
    41641 tcgtggccca atcgccagcc atttggcgat cgatactcgc tgcgcgttac caccagaaag
    41701 cgtattcacc ggaagatgag gatcagagac tttgatggtc aatgccttga ttagcctgtc
    41761 caccaggtca cgaactttag tttcactcag aaagccgaag cgatctttta ccttgtgaaa
    41821 aacagtgcta atgatgttgt cttcaataga ttgcgccatc accaaaccgc gcgacatgcg
    41881 atcttccgaa acataaccaa taccgtggcg gatagcgtcc tggttactat gcagtgtaac
    41941 cggctggccg ttgatgagga tctcgccagc atccggtcgg gtcataccaa acagactcag
    42001 acataattcc gtgcgccccg caccaagcag gccaacaatc gataccactt cgcccgcttc
    42061 cacccgcaag ttaatattta gatattcccc atgacgactt aaattacgca cctccagcac
    42121 cggggtgctg gattttccct gccacaactc tcgcacctga tattcaaact cctggccggt
    42181 catcaggaaa ccgagttgtt ttgtggtcat ctctgcagcc ggaaaagtcc cgaccagctc
    42241 accatctttc agcactgaaa tacggtcgga aacttccatc acttcttcca gacgatgact
    42301 gacgaagacc acgcagatcc cgcgttcacg caattgatgc accacctgta ataacccttg
    42361 cacttcctga tgggtcagcg aagcggttgg ttcatccatc acgatcaacc gtgcgtcctg
    42421 cgccagtgca cggcaaatag ccaccagctg acagcgggca attgaaagct cagaaacgag
    42481 tgtatccagt ggcaatgtga cgttaatact ggtcattgcc gcctgcgcca cctcacgcag
    42541 acgacggcgg ttaacaaaca gaccgtggtg atagtgattc acggcgatat tctcccagac
    42601 actcaggtta ggaaataaag agaggtcctg ataaatcacc tgaatcccct gcgccaccga
    42661 agcggcgggt gtcagctttg accagttttt cccaccaagc gtaatttccg ctccctcatc
    42721 cgggcgataa acaccggaca taattttaat caacgtcgat ttaccacagc cgttttgccc
    42781 ggcaaggcag tgcacttcac ccgacataaa gtcgagagaa acatcgcgca gcgctcgcgt
    42841 ggcatgaaac gttttgttga tatgacgaag ggaaaggaaa gtttccataa catcccctgg
    42901 caataagaat cggggctttc gccccgaaga aatggattaa taaagtgagt cgatattgtc
    42961 tttgttgacc agtaatacct tatggaaacg gataattcgc ttatccatat ctacgtcggc
    43021 cttacccaga ttctgcattt ctaatccagg tttgatctct tcacccttca gcaacgtgct
    43081 ggcgacggct gcgagtgcgt aacctgcaga ggccggatcg taagtaatcc cttcggtgat
    43141 atcaccactt ttaatcagtg atgccgcctg tgaagggatc atcatgccat agactgcgac
    43201 tttatttttc gcccgtttct ctttcaccgc acgtcccgcg ccaatcggac cgtttgaacc
    43261 aaaggagaca accgctttca agtcaggata ggttttcatc aggtccagtg tggtacgacg
    43321 tgagtcatcc acactctcgg caaccggcat gcggcgggta acttcatgca tatccgggta
    43381 atgctctttc tggtatttca ccagcaagtc agcccataag ttatgctgcg gcacggtcaa
    43441 actacccacg taaatcacat agccgccctt gccccccatg cgtttcgcca tatgctcaac
    43501 atattcagcg gcaaattttt cgttatcaat gatttcaata tcccagttag cacttggctg
    43561 accgggggat tcgttggtca gaaccacaat tccggcatct cgcgcttttt tgaataccgg
    43621 ttccagcacg ttggcatcgt ttggcacgat agtaattgca ttaaccttac gggcgattaa
    43681 atcctcaata attttaactt gttgcggagc atcagtactt gaaggcccca cctgtgaggc
    43741 attaacacca aaggctttac ccgcctcaac cacaccttcg cccatgcgat taaaccacgg
    43801 cataccatcg actttagaaa tattcaccac gactttttcc gctgcctgga gcggcgcaga
    43861 aattagcgca gcgcctaata acagcgaaga caccatattg ataacaaaac gtttattcat
    43921 catttcagcc tcattgcagg gtagtcagga agtgttcgcc caaattagcg cgctggagag
    43981 aataagaatt ttcgaatatt tttatgcaga ataaacagcc ctatttcagg cagctattaa
    44041 aaatatggtt ataaatatgg acaaaacggg cagcaacaat aagtgtgaca ttcatcacgt
    44101 aaaaaaatag caaaataaac aaaattagca atattttatg tgtgtgagtt tatttcgcgt
    44161 agataaatag ttatctacac aacgtcaata agggcatatt cttcaaatat aacgtccatt
    44221 tctggtgaat agcttccttc tgcctggaaa aaacgacggt gttcattacg ccaatattca
    44281 agactgaggt caccttcacc ttccttacgg gcaagctcca cggtgacatc agaaaagcgc
    44341 agtaaatgca ggccaatcac tctgataaca catacaggct caccacggct attttctaca
    44401 atcttatact caccaatcat cggaaatgcg ttgtcttcaa tacatcccgc cagcgaacca
    44461 caggaagctg ttttaacacc agtcgcaatc aacgttgcga ggtgatcggc caacgctgct
    44521 gaatcgccaa aagtacaaaa ggaagcatgg ggatattttt gtgagaattt ttcttttatg
    44581 gtcatggcaa tatttttgcg attacggaaa aacaaatcac atcttaatta ctgttggtaa
    44641 ccatcagcaa gagtatcatt ggtttttcga tactgaatct tttttatccg aagcaggtca
    44701 catttatggc ctgataaata cctttgttaa aactcacttt tgtgtatttc tctcaaataa
    44761 tcccctggaa attatgccgc gagattataa agttcaggat cattcattag caaaccattc
    44821 ccgccccact ccctggggct taaatctctt acaattcacc gttgcaggcg tttcaaatgc
    44881 gcatcaacct gccacactcc cccacaccag ttgcccttta tggaacgttg cggttctcgg
    44941 cgagatacgc gccaccgcct cggcggaaca ggaggcgtcc accagcacaa agctggcatc
    45001 atcctgcgct tttggccata cacgctcgcc tttttcattc agcggcaata catcgccagt
    45061 ggctagaaac agcgaacggg agaggttctg ttcgttagga cgaatataga gctgcgcgta
    45121 gagattggct ttttccagca tgtcgcccag accataaggc gaccagtggt cgataacgct
    45181 gtcagtgcca gtcatcactt ttacgccttt gtcgtgcaac tgtttgagcg gcatatgcag
    45241 cgtgccaatc ggcaccgtcg aggcgataga aatttgctgc gccgccatcc gattcgccag
    45301 cgcatcgacc tgttgttcgt tgagcgtagc cagcgcaaag gcgtggctga tggtcagctt
    45361 acctttcagt tgcggcgttt tctctaccgt ttcaaccata taattgatgg ctgtcacgcc
    45421 cgacggagtg gtttcgtgca ggtgaatatc gacacctttg tcgtagtcca gcgcaatctg
    45481 aaacatggtg tcgagggatt tttccatcgc gccatcgaca ctggtcgggt ccagcccgcc
    45541 gacgtaatgc gcacccgcct gcatcgcttc gcgcattaag ggttccgatt tcgacagcag
    45601 caaaccgtgc tgcgggaagg cgacgatttc acactcgaag cccgcctgac gtcgcgccag
    45661 caccgcctgc aaattctgca gatttttcag gccggaaacc ggttcgatat tgcagtggct
    45721 gcgggcaatg gtggtgcctt tcgactgcaa tagatcgatc agtttttctg cccgttcctg
    45781 cgtgtacggt tgcagttccg gcagcatttt ctgctcaagc ttgatcatgt cctggatagt
    45841 ggtgcctgcc ggacgattga gcgagcgcca cggcccgccg tagaaggttt tgtcgagatg
    45901 aatatgcatg tcgcgagtgg tgggtagcat caacttaccg ccagcgtcat agtgcggcag
    45961 cgtggcgtcc ggatgctgct tgttctcgcg cagggcgaca attttgccgt cctgaatctc
    46021 cacggtctgg cgcgccgtgc gggtctgcac cgccacaccg ttttcgtagt caaaaccggt
    46081 ttccagcagc acgttatcga gatagtaatg cgggtcagtg attttcatgg tgttgttcgc
    46141 ttcgcagttt agggtgccag ctaccgccgc atgggcgagc ggcacagagg taccaaacag
    46201 cgcggcggcg gtgaccatct taccgctctg gctcagaaat tcacggcggc tattgctttc
    46261 tttcatccta cgtccttacg ttttaataat atgggtgccc gtttcaccgc gcagcgccgc
    46321 aggcaggcat tccggcgtgg tgataatcac ttctttgccg ccctgctcca ggaacgtcag
    46381 gctggcgatg atttttggca acatgctgcc gggcggaaaa tgcccttcct gcatatagcg
    46441 agtcatggtg gcaatatcca cccgatccag cgcctgctgc tgcggtttac caaagtggat
    46501 acagactttt tcgacgccgg tggtgatcac cagaatgtcg gcgtgaattt cacgggccag
    46561 cagcgcggta gagagatctt tgtcaataac cgcgtccacg ctttggtaat cccccgcttc
    46621 agtacgcact accggaattc caccgccgcc cgcgccaatt acgacaaaac cttgttggat
    46681 cagcgcctta atggcgggtg cttcgacaat acgtttcggt tccggcgagg cgaccacgcg
    46741 gcgatagccc cgtccggcat cttcaacaaa acaccagtca gggtttgcct tttgtagttt
    46801 gtcacgctgg ctttcactga agaatgcacc aatgggcttg gtgggatggg caaaacctgg
    46861 atcgttttta tccacttcca cctgagttac cacggtgacg gcttttttct cgccgtgacg
    46921 cgccagccgg ttattcagcg cctgttggat cagatagccg atgccgccct gcgtatctgc
    46981 cacacagttc gccagcggcg ttaagggcag cccttcgcgc tcgtgggcaa tctccgcacg
    47041 gcgtaaatcc agcccgacct gcggcccgtt accgtgggtc agcacaatgt cgtaatcgga
    47101 agccagcatt tccagcaccg tatcggccac ggctttcacc gcctccgcct gatgctcaat
    47161 cgactggctg gcgttatctt tgataatgct gttgccacca atggcaacga ccacaagctc
    47221 tttcatgttg ttatgtccgc tacagagggt gattaggtta tgaccaacgc cagactgcct
    47281 gatgcgctac gcttatcagg cctacaattc tcgggccatc cgtaggccgg ataaggcgtt
    47341 cacaccgcat ccggcataaa catgtaagtc agacgccgta acgttcgcac cagccgagaa
    47401 tggctttctc gaagcaggcg aatggtggat gcacaatgcc cgcgccaatc atgccgacgc
    47461 ccgcatcttt atgggcgatg gcggtgttga tcaccggcag aatgccgctg ctacccacgc
    47521 gggtgatgtc gattgccgac ggcacgccca taaaaccgag cagcggaatg gtgacgttgg
    47581 ggttttcgcc aagggtgatt tcgcgcatct gacgggagaa atcgatagcc tcttccaccg
    47641 tgccgcccac cagtgcgacg attgcaggcg cggtcgccat ggcaaacccg ccaataccgt
    47701 aggtttctgt gatggcgctg tcgccgatat ccagccccga atcttccggc ttataaccag
    47761 caaacatcgg gccgatgacc tgctgcgctg ggccggtaaa ccactgcccc ggcaggccgc
    47821 tgacccgcag gccgaactcg acgccgttac gcgccatggt ggtgaccacg gtgctgtatt
    47881 cgatgccgtg cgccgcatcc atcgccgctt tacacatcgc catccacgtc gggccggaga
    47941 agtagtcgct gctggcgaca aactcgaaca cttcgcgctg ttgctcgacg gaatagcctg
    48001 cctgaatgat ccccggcgtc agtgcctgaa tcagcagcgt cgtcccggcg ttattgcggt
    48061 tatggcactc atcgcccata tgcagcgcct gcgccagcat taagcgcaga tcgatctcac
    48121 cgataatttt catcgcgtcg cgcagcattg gcccctgcac atcgcgcatc cagttgaggc
    48181 ggtcgatcac gctctgatcg ttggcaccca tacgcaaaat cttcgccatc tgctcgctca
    48241 tattggtata agcgatgttg ccgtaggttt tgtttttcac gatgtgcata aacatcgagg
    48301 ccgaggtaac gcccgccatc gatcccacgc agtcgtgttc gtggcacggc gagaaggtga
    48361 tctccccgga ggccgccagt tcagtcgcct catcgagatc tttcgccagc ccttcgaaca
    48421 ccaacgcccc ggtgaccgcg cctttcatcg cgccgcacat tttttcccag gtgatcggcg
    48481 gcccggcgtg aagaatggtt ttcggcgtca tgcccggcac cacgttaatc gcctgatcaa
    48541 aaccaatcag caccggatgc gactggataa tgcgctccag cgcctgctgg ttagcggcgg
    48601 cgattttgtc tgccagcggc gaatcggcaa tgttatccag cgcctgcacc acctgcatat
    48661 tgccctgccc cggcggcgtc cagtcgagtt gagtcacttc tacatgctgc tttttcaggt
    48721 catcgctaaa catggcgata ccgacgttaa taacgttcaa cggttggcta aacagtgact
    48781 ggctcatcag gcttcctccc ctttgcagat aaattcacgc gccagcaatc cggtattggt
    48841 gctgctgctc gccagaatca ctccggcatc aagcagcatc tggctttgtt gttctaatga
    48901 tggcgtatcg agatcggtgc ccagcacata ggcgagaatg atcaactcgc gtccttcggc
    48961 ggcggcgatc gctttcgctt ctttgatcgc ctcgatggtg gagccgaccg gatcttcatg
    49021 cgatccaaat ccgagcacaa aatccatcac gatcaccgcc acttctggat cgcgcgcctc
    49081 ttcgatcaag cgactgatgc ggttggtggg gtcaatcatt ggatgcggct tgccgttggt
    49141 gaagtcgtca tcgccaaagt cgaggaaggt gtgtttgatg ctacggttga tatcttgcag
    49201 gcggaattcc ggatcgggct gaatgttgct gtagacatcg ccgtgttttt ccatcaccgc
    49261 gaacatggtt tcgtcacaca gcgtgccgcc acagaacagg ccacgaatgt acttctgctg
    49321 cggttgcagg cgagcacgta cgtcagcaat caacggctgg ttcagcgtat gcaggtcgag
    49381 atgttcctgt ttcacgccgg agagcatcac cgctttcaat gccgcctctt tgctgccgcg
    49441 ggcaaactgt agcccctgct catccactgg cgtttcgcca cgaccgagga aacagaccac
    49501 caccggcttg cggcaggcgc gcgcgcgttc cagcactttg cgggccaccg caggcgcggg
    49561 cggtttggag ataagcacaa tgatttcagt ttgcggatcg ttttccagca tgccgatggc
    49621 gtcgagcatc atcaggccgc cgattttctc gctcaggtcg cgcccgccgg tgccaatcag
    49681 ttgcgaaacg ccgccgccaa attcatgaat gcggacgctc agctcctggc tgccggtgcc
    49741 ggatgcgcca acaataccga tgttgccgcg acgcacggcg ttaccaaaac agagcgccgc
    49801 gccgttaata atcgccgtgc cacagtctgg ccccatcatc agcagccctt tttcgtgggc
    49861 cagttgcttg agcgccaatt catcttcaac tgagacgtta tcggaaaaca gcatcacgtt
    49921 gagatcgttt tgcagcgcct gacgcgcttc gcgagcggca aacagaccgt tgaccgaaat
    49981 caccgccagg ttactttccg ggatatgctt tttggcgctg gcaatagtgg cgtaacgcgc
    50041 ctcatgcgag ccgctttgcg ctttggtgtt gaacagttct tcaatctcca ccagcaactg
    50101 ttcgttgtcc gcgcccgctt tgccgttgat gacaatcatc aggtcgccgt ttttcgcctg
    50161 ttccagctcc ggcgtcagca gtcctaaatt tttcagtaca cctttgttca tttcggtcgc
    50221 catcgccaca aatgcctgct cgacgccgtc gagtttattt gcacgcgtgg agatagacat
    50281 cagcgagaca gaatcaaaat aggtattcgg tttaatgact attttaactg acataattcc
    50341 ctccgtaggt ttggctcagc gcacaaccat cggccatgcc atacagcatg tcgcagccgg
    50401 aactggagcc aatatgttta attttttcta ttgcctgagt tgcgttccca gggatgtcat
    50461 aaataatgtt gtgaataaaa cgatgaatat tttcccggca acgttgttgt aatgcggctt
    50521 ccagcgttat agcacttaat aatgtggtgt tatttctgcc gcgctgcata ccgagataaa
    50581 attcctcttt gtatttttcc gacggatgcc cgggaataaa taaaataagc gccagacctg
    50641 ttaaataatc gtcggctgat ggcgtaaggc caatccctaa cccaatcata ctggcgaccg
    50701 ctgcggcgat attttgtttt tcgtttactg cctgaataac tgcccgtcgt ttaatatgta
    50761 gttctttatt taacgcctga taaaacggat tatcgccgcg ataattaaac agggtttcat
    50821 tttcccccag gtgctgatga ataatgtcgt gccactgttg ccaggcgata aggtgaaaat
    50881 tcacagcggt catttgcaag gttggggaca gccaacgccg acaacgactc atctctatat
    50941 gaagatgttg accaaccgta ataccttgat cgtcaaactg aaccttatca ccatgccgga
    51001 acagatcatc aaagtgagtg agtgccaacc gacaactgtt tggcgcattg tcgtactctt
    51061 cacaaagcag cgtcagcaac tgctggcgag ccgggagtgc gatatttacc gctctggcaa
    51121 agacctgttc aacctgtcct tgcccccgct gcgccagaaa atccgcatcc gcagttagcg
    51181 cccacacaca ccgtctttct ggtgtgttga tagcaagcct cccggtttat gcacctgcgg
    51241 caatcagtaa ctgcgcaatc tcttcaaagc cccgttcccg cgccagttcc agtggcgttt
    51301 tgccatattt atcggtcaga tgcgggctgg caccgtgttc cagcaataac tgcacaatcg
    51361 cctgctgttt aataccacca tcattaagca caatcgcttc cagtagcggc gtccagccta
    51421 catggttggt ctggttaacg ttaatctccg tatgcgccaa aagctctttt acaatactta
    51481 aatggccttt ttcacaggca ggcgtcaggc cgacaccgcc aaaacgggtt acgcaattaa
    51541 gatcgggttt agccggtaaa ataattcgta gtagcgttaa atcatcgttc agacagctaa
    51601 ttaaaaaagg atttaaacag gtatgatctt gcttattaat atccgctccg gcatcaatta
    51661 atgcctgaac gcaagcatat tgctgatata aacttgccag cgtaattgcc gttttcccct
    51721 gacgatcgca ggtattaata tcgacaccca gcgcaaggca ggtttttact ttatcgatat
    51781 caccctgttg tgcagccaat aaatagtcgg caggtagatt ttttatactc attcacattc
    51841 ccctggtttt tgtggctgtt ttcgatgaat tgagaatagc aacgataatc tgataaaaga
    51901 acccgcttaa atttaattcg ctgtatttcg cctttttgtt gaatgatgtt caacaatctt
    51961 ttcgcagtgt gcggtagtgc aatatttgtt tctttgaccc gatacccttt cactcaatca
    52021 ggttttattt ctctatagtc tgcacatgta agagtagctt tcgtccatgt ctaaccagag
    52081 gggaacaaga tgaacggact cacggcaacg ggtgtcaccg tcggtatttg tgcagggctt
    52141 tggcagttag tgtcttcaca tgtcgggctc tctcagggat gggaattatt aggaaccatt
    52201 ggcttcgtcg ccttttgcag tttttatgcc gcaggcggca gtaaatcggg gtttatcaga
    52261 agtctggcgg ttaattattc cgggatggtg tgggcatttt tcgccgcgct ggctgccggt
    52321 tggctggcct ctgtaagtgg actgtccgcg ttctgggcga gcgtaattac taccgtaccc
    52381 ttctcggcgg tagtggtctg gcaagggcgt ttctggttac tgtcctttat tcccggtggc
    52441 tttctcggca tgacgctgtt ttttgccagc gggatgaact ggacggtgac gttactgggt
    52501 tttctggcgg gtaactgcgt ggggataatt tcagaatatg gtggacaaaa attaagcgaa
    52561 gcgacgacta aacgcgacgg gtattaaaag ttattcaaaa atgattatct atctttaacc
    52621 gatacctcta cagtcatagc tggagaaatt catagtagat aatggcgaga atggtttaat
    52681 gaactcaatt tttaccgaag agaatctgtt ggcatttact accgctgcac gttttggcag
    52741 cttcagtaaa gccgcagaag agttgggttt aaccacttcc gccattagct acaccatcaa
    52801 gcgtatggag acggggctgg atgtggtgct gttcactcgc agtacccgca gcattgagtt
    52861 aacggagtcc gggcgttatt ttttccgcaa agctaccgac ctgctgaatg atttttatgc
    52921 catcaaacgc agtatcgata ctatttcgca gggcatagaa gcgcgtgtgc gcatttgtat
    52981 taatcagctg ctttatacgc ccaaacacac cgcacgcttg ttacaggtgc tgaaaaagca
    53041 gtttcctacc tgccagatta ccgtcaccac cgaagtgtat aacggcgtct gggatgcgat
    53101 tattaataat caggccaata tcgccatcgg cgcacccgat acactactgg acggcggcgg
    53161 tattgattac actgaaattg gcgcgattcg ctgggctttt gctatcgcgc cggatcaccc
    53221 gttagccttt gtgccggaac ccatcgccga aagccaactg cgtctctacc ctaatattat
    53281 ggtggaggac accgcgcata cgattaataa aaaagtgggc tggttgctgc acgggcagga
    53341 gtcgattctg gtgccagatt tcaacaccaa atgtcagtgc cagattttag gtgaaggaat
    53401 tggttttttg ccggattaca tggtccgtga ggcgatgacg caatccctgc tggttacccg
    53461 acaaatccat aatccgcgcc aggattcgcg catgttactg gcgactcagc attctgctac
    53521 gggtcaggtg acgcagtgga ttaaaaaaca atttgcgcca aatggcatat taacggggat
    53581 ctatcaggat ttactgcatc gggagaatta atcgctgcca acctcccgat gcgctgtgaa
    53641 tagcggttta catcaaccac ctgctttcat tacccattca gagataaatt tattacccgg
    53701 tactggcgga gagtacaaat agccctgcaa aaagtgaacg cctttaccga tcattaaatc
    53761 cgcctgctcc tgggtttcta ccccttccgc cacgatactc agaccaggct tacgcgctag
    53821 ttcgacaata ttgtccacaa tatgaccgga gatttcgtcg acactcgcca tttgcacaaa
    53881 tgacttatcg atcttaataa aatcgaccgg gaacgcctgc aagtaacgat aggtcgcata
    53941 acccgtacca aagtcatcca gcgcaaaggt aatgttgtgc tgatgaaggc tgtcaaatat
    54001 cgctctggct tctggcgtta ccggaatagg gttacgttcc gttagctcga gaaccagctt
    54061 gattttatcg ttacctaatt tcttaaccag gttcagacac tctttttcaa atcccgctgc
    54121 caaaaaacaa cccgccgaga cgttgatgcc aatatggaaa ttgtccggca gcaaatgttt
    54181 taccggcatc agaatatccg cagtctgttt catcagttgg cgggtcatta tgacaataag
    54241 accggatgac tccgccagag gaataaactg atccggtggg ataattcccg tttgtggatg
    54301 ttcccagcgg acaagtccct cacagcccgt cagtacccca gtctgcgcgc agaaaaccgg
    54361 ttggatccac ggtttgaatt cgtggttttc caacgccaga ctgatggctt caggcgtgac
    54421 gatatggtga caacggttat cagggatata aaaattattt ttatttcccg tgccactgat
    54481 gacttgcgga tgatattgaa aaaagatatc ccgccagaag gtaatatcac tctggatgcc
    54541 tagtttttca tacagctgct tcttttgatg tgaaattgtc tttgcactgc gatttctgta
    54601 ctgtgagatt tctgtaaccg acattccctc cattagcagc ttgagtaaaa gccgttcttt
    54661 ttcggacacg ataccaggca acgtcaaatt caccgttgcc ccgaactctt ccaaaaaaac
    54721 actcaaatca tgcgaagcca ttgaacacac cttgattaaa tcttgtgcgc cagctaaatc
    54781 tgcgagtctt cactctgact gataaagctg gctgcaagaa aatgacacag agagccgaat
    54841 tatctcccgt tcggctctct ctccttttac tcattattca gatcagaatt gccacttaat
    54901 gccaaccatt gcagaggtgt cattatatcc cctatcggca acctgaacgc ccacattccc
    54961 ccagacattc aggttggcat ttagctgtcc ttccaccccg gtttttatct cagcaatatt
    55021 tcgggctcca tcctgagtga cggacacgcc atccatactg gtgctgaaat ccttactgtt
    55081 atgcagccag ttcacttcta caaacggctg gaactcgcgg gatttaccgt catccatttt
    55141 atggtggctc ttcagccagg tttttacgcc aagtcgggtt tgaacattgc catcaccgtt
    55201 gctatgaacg agggttccgt tgctttcgcg gtgcttatcg gctttgactc ccatccaggt
    55261 aacctgtgct tgcggctgaa cataccattc attacgcgtt ccctggttgc cattaaattc
    55321 agctaatttg tgtttgtatc cagcttccag tgaagcggta aatccttttg atttatagga
    55381 ttcactttgt aagtcatccc ctttcactgt gttatcaaac cagctgtact gcgcccaact
    55441 gtcgagatac gcgccattac gcgactcgtc atcggcatac caggtggcat agaggccggt
    55501 gctatatccg ttcacactcg cttttgcacg ataaccggtt cgcgaggaaa tggttttgct
    55561 gtcgctgttg ccatatcccg ccatgacccc aacatgccag ctgtcgctgc cgttttggct
    55621 ccactgcgcg acatcgcctc ccagttgcag aacatagcga ttgctttggg ttttcagctg
    55681 gccgctgcca tcacgccatt tattatgacc accttcatgg cgcatccaca tagtggtttg
    55741 tttctgctca cccgtcacca tgtcggtata gtacgtatta cccagacgct catgcagacg
    55801 cgtggtgaac attgtattcg ctgctgcaag gttcgcaatg tagctacccg cctccggtcg
    55861 caggtcatta tccacattca gatccggacc cggcgtaggt gtcgggttag ggttcggctc
    55921 tggattcggg tttggctccg gattcggcat cgggtctggc tccggctgca gttcaggaga
    55981 atcactgccg ctggtcagat accagttacc acgatttgcc ccttgtccac gcgcgagagt
    56041 gtagtcatac gcccccgcaa cgatacgacc agcctgaaca aattcgccct cagacttacc
    56101 gtctacatgg ataagttcga taccgttaag ggttttcgca cctgtaccgc cagcgttatt
    56161 caccgtaacg gcagtcgtgc cgctagtatc gccctcgaca accaatttat cggttactga
    56221 gtcatcgcca ttcagtaccg tattcattac tagttgaccg ttattaccgt ggtagttccc
    56281 cttcaccact aacacattgc cagcttgctg tcctgacatt ccggtcatca gcgtaccgtt
    56341 gttggtcaga ttgccgccca gggtgtaatt cacagacgca gccgctcttt tttcagcgct
    56401 attattcaac gccagggtac cgttgttctc aacgtttgcg ctacccaatc cctgcgcatg
    56461 acttaccagg acattagccg aattagcaat gttcacattc gccgtcaggt tgctgttatc
    56521 gcccgcgatg tccagcgtgc cgccctgaat attcagctct ccgctccccg ttaacgaacc
    56581 ggttgaagtg cccccgttgg taaccgtcag actgccgcca tttaagctca gcagtgaatc
    56641 ggcgctgcca ttgagcgtgc ccacggtctg gctgtgacca ttcatatcca gttcagtctc
    56701 tgccgccaga cgcagttcat gggtattacc caacacgtta tcgttattca acaaaagcgt
    56761 cccactgcgc agatcggtaa caccggtata gtcgttgtct ttgttagaaa gcgatacggt
    56821 ctgatccttc tggctgctga atgccaggtc accgctgccg gtaatctttg cgctgagatc
    56881 ggcggcattc tcgcttttac cgttagagct cagcaccaga gcatcgctat cggtagcgtg
    56941 taaatcaagc tgggtcaggc cgtaaccgat atacagaccg tcattgttta ccccactcgt
    57001 cagacgatag tcgtaagtgc cgacggccgc tttttgccca ttctgctgaa tatcacgttg
    57061 ggcactgctg gagaggattt gcccattttt atcctgcaat tgcagattgc ccgcatcgcc
    57121 cagaacttcc gcaccttgcg catcaaccaa cttaatggtg ctgttaccat catcgacttc
    57181 agtgagcgat aacgcagagt caatatcacg agatactgag cttacaacgt cactgtcaga
    57241 aacctgaatc acaccctcgc cgcgcaaatc cagcgtttta ctaacgttga ccgtcccttc
    57301 tgtcatctgt gcacctgctg tcagggcacc aaaatcaacg gttccgccgg agaatcccaa
    57361 agtgctaatg gagtgagcgc ccttacccac tgttaccagg cttccctgac ccgcagtgat
    57421 cccgcctctc tgcagaaact cagcattctt ttccaggtta aatgtcgtgt tctggaacgc
    57481 cagtgaaccc tggaaccagt ctgtataagc aaactcatcg aaggagaatt cgtgattccc
    57541 catgtttatt tcaacaatac ctctaccttg aagatcgtta tcaaataccc aatctttatt
    57601 ggcattgatt tgcagtttgc catcaacatc caggtccgca cggccgatgt tcttgtcttc
    57661 agaaataacc gcgacagcac cagaagcgac atcaatatat ccgctgaatg catagttatt
    57721 gccggtcagt gccactgtcc cactgtcgat acttattgta ccattgccgg aaatcttatt
    57781 ggcaaaggtc atgctatcgt cagccttcag gtgtaatttc ccgcggttgt tgatctctgc
    57841 tgtacctata tttttggtga tccctaaagc gccattttgc tcaattttga ctttaccact
    57901 aaaggcagag ttatcaccgg ttaagtaagt cgtgccattg agcgcattga tatagcccag
    57961 gccctcgctg ccactgacaa tatccgcgga aatagtcgcg tttttatccg tgtggtttaa
    58021 ggtgattttc ttatcggatg tctttgccca cacaaactca attttttcgg catcaataat
    58081 ccctgcagcc ttcgcagcac ttccttcctg tgcacctaac gctaactcag agttggtgct
    58141 taaactaatt ttcggtgcgg atattttacc tccatctgat acgactaatg ttgtatcaga
    58201 acgttggtcg taataaccca ggctaatatg ttcacgagca ttaacttcac caccgttatt
    58261 aaccgacagg aactgattac cgccatatcc gccgtaaacg cccataaaga aggtccctgc
    58321 atttacctga ctaccttcgc cgcttacatt cccctgcgta taagtcagac gactggtgcc
    58381 cttaacatga attttgccgc cattggagac attaaaatag ccttgatcat gtctcatgcc
    58441 tgagtttgac tcatacaaat catcagcata taactcgctg ccagcattgg agacattcag
    58501 gaaccccgta cctttcagca aaaagttaag cgggccattg attgttacct ttcctccggt
    58561 aatatccaac ccaccaccag aagcgagagt cagacgcgga cgggaagtat ctgtcgtatt
    58621 gattaccaga ttggcattgt cagtcaccgt aatacggtaa tcgatgctct ggttctcttt
    58681 gccaaaatca atagctttat cctggtttac gatgacatca tcggcgaata ccagagatga
    58741 atataaactt atcgcgctaa ttaaaacagc ccgggacttt tttcctttta ctctgctccc
    58801 cagctccgag cagacgctcc aacagttacg ggacctgttc cactttagcc gatatatttt
    58861 attcatcaca atctccagca atacatccaa ataaaaccaa gattgcataa acagcaacgc
    58921 attaaatgcc attctggtta ctgttcatcg catataaaaa ttcaaaaatt ttgcatagca
    58981 ttggcaacca catatctgag tatgtagttc agagggtaat aaaatagcaa gttattactt
    59041 aaaacttatt ttaagttaac actcttaact ttatcattac attcctccca gtctctaata
    59101 cctgcgcatt atatgtatcc aggaactcaa atcaactca
//
LOCUS       DAZUDJ010000024        58303 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.024, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000024 DAZUDJ010000000
VERSION     DAZUDJ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 58303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58303
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.024"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..241
                     /locus_tag="ACHY1N_002030"
     CDS             <1..241
                     /locus_tag="ACHY1N_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3289 family protein"
                     /protein_id="HFS4044350.1"
                     /translation="ISAQKISLLSFQNYAIGWSATIHFVAQDHFGLDVTDIKNKTYSK
                     YRFFRIWFFLQRHKDFAFKPFFTNFNTIERIENYL"
     gene            238..729
                     /locus_tag="ACHY1N_002031"
     CDS             238..729
                     /locus_tag="ACHY1N_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF943 family protein"
                     /protein_id="HFS4044351.1"
                     /translation="MKSKLQKIILCLFLLCCIYNLWTLRPVQILYTYSDAGNSVFLVV
                     DHLPWTDSDKINWYLKHQNEIKNQHPLPEGSWHTWYVIDIGNGFTDYKKYIEGPYEDL
                     YCFPTIKSNDNCIVKNYLMVINEYPYRNTHIGINDFTEYQLTQENKIERVFNPHDFKK
                     DNF"
     gene            complement(771..1721)
                     /gene="corA"
                     /locus_tag="ACHY1N_002032"
     CDS             complement(771..1721)
                     /gene="corA"
                     /locus_tag="ACHY1N_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HFS4044352.1"
                     /translation="MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL"
     gene            complement(1873..1929)
                     /gene="ysgD"
                     /locus_tag="ACHY1N_002033"
     CDS             complement(1873..1929)
                     /gene="ysgD"
                     /locus_tag="ACHY1N_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YsgD"
                     /protein_id="HFS4044353.1"
                     /translation="MDTPSRYWLTILSSRINS"
     gene            2091..2855
                     /gene="yigE"
                     /locus_tag="ACHY1N_002034"
     CDS             2091..2855
                     /gene="yigE"
                     /locus_tag="ACHY1N_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HFS4044354.1"
                     /translation="MAHRLLIGKGMITLNLKRIFLTLTLLPLFAVAADDCALSDPTLT
                     VQAYTVNPQTERVKMYWQKANGEAWGTLHALLADMNSQGQVQMAMNGGIYDESYAPLG
                     LYIENGQQKVALNLASGEGNFFIRPGGVFYVAGDKVGIVRLDAFKTSKEIQFAVQSGP
                     MLMENGVINPRIHPNVASRKIRNGVGINKHGNAVFLLSQQATNFYDFACYAKAKLNVE
                     QLLYLDGTISHMYMKGGAIPWQRYPFVTMISVERKG"
     gene            complement(3002..5164)
                     /gene="uvrD"
                     /locus_tag="ACHY1N_002035"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             complement(3002..5164)
                     /gene="uvrD"
                     /locus_tag="ACHY1N_002035"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HFS4044355.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIA
                     WLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAET
                     IRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFG
                     EGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLESV"
     gene            complement(5248..5964)
                     /gene="yigB"
                     /locus_tag="ACHY1N_002036"
     CDS             complement(5248..5964)
                     /gene="yigB"
                     /locus_tag="ACHY1N_002036"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HFS4044356.1"
                     /translation="MRFYRPLGRISALTFDLDDTLYDNRPVILRTEREALTFVQNYHP
                     ALRSFQNEDLQRLRQAVREAEPEIYHDVTRWRFRSIEQAMLDAGLSAEEASAGAHAAM
                     INFAKWRSRIDVPQQTHDTLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHG
                     RSKPFSDMYFLAAEKLNVPIGEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTW
                     DSRLLPHLEISRLASLTSLI"
     gene            complement(5964..6860)
                     /gene="xerC"
                     /locus_tag="ACHY1N_002037"
     CDS             complement(5964..6860)
                     /gene="xerC"
                     /locus_tag="ACHY1N_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFS4044357.1"
                     /translation="MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENG
                     LQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVS
                     APKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
                     DLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISAR
                     NVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYT
                     HLDFQHLASVYDAAHPRAKRGK"
     gene            complement(6857..7564)
                     /gene="yigA"
                     /locus_tag="ACHY1N_002038"
     CDS             complement(6857..7564)
                     /gene="yigA"
                     /locus_tag="ACHY1N_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 family protein"
                     /protein_id="HFS4044358.1"
                     /translation="MKQPGEELQETLTELDDRAVVDYLIKNPEFFIRNARAVEAIRVP
                     HPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSL
                     DDMLMRFHRWARDLGLAGASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLH
                     EIALMLPELLERWIERV"
     gene            complement(7561..8385)
                     /gene="dapF"
                     /locus_tag="ACHY1N_002039"
     CDS             complement(7561..8385)
                     /gene="dapF"
                     /locus_tag="ACHY1N_002039"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFS4044359.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL"
     gene            complement(8422..8625)
                     /gene="yifL"
                     /locus_tag="ACHY1N_002040"
     CDS             complement(8422..8625)
                     /gene="yifL"
                     /locus_tag="ACHY1N_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFS4044360.1"
                     /translation="MKNVFKALTVLITLFSLTGCGLKGPLYFPPADKNAPPPTKPVET
                     QTQSTVPDKNDRATGDGPSQVNY"
     gene            8975..9529
                     /locus_tag="ACHY1N_002041"
     CDS             8975..9529
                     /locus_tag="ACHY1N_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3304 domain-containing protein"
                     /protein_id="HFS4044361.1"
                     /translation="MGLFTQLEKFDQKLTRGYARWGRWVWRTLIVVPVLVVLWNIGQA
                     VWGGPRGGVILEIHSEIDRPILGFSVNGVAGANAFANGGGSTTCCGDVSGDTAEVIWT
                     LSTTRTQYNAGMRLEKRNMTLPLPKREWGEDFLHVHFMPGDKVLLGWSKDSFSPYEDL
                     HNGGYKTRVRQDVKDKLYGTGKMN"
     gene            9867..11375
                     /locus_tag="ACHY1N_002042"
     CDS             9867..11375
                     /locus_tag="ACHY1N_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DKNYY family protein"
                     /protein_id="HFS4044362.1"
                     /translation="MIGTSRQDGFMHYRNVVCLLSCSLFLSSAWGCRLDPPEHNIYQK
                     QGKGVVYLRPYKETNLSLPDVNYKSLRRLPNLLIDPTTLDKWDKVPPLTDLTTDYLYE
                     GAQAWYPHYSWHSDGRYILYAGEVVQNPPDKPPVDVASFKAWGDFAADKHSLYFEGKR
                     TDNNGGGNRLDIKTLHQVEFRPPWDPDLLGLILRDANFLYINGHRLADPDSFRVLAQK
                     SWDQRGKFSTAFNPCVAMPFGPWDTLARTRTKILINGEQLDADPDTFSVVRWMPGSLL
                     TWRDKNGLQRKVLDKENLEWDEDLTKHCLDFSLLEKKVFWRKGPACKQEELPGLDPEQ
                     FQPISDAVAQYQDSLYTIIETESGDRKLEIVKLDDPNLIINKRFNAGKRHGYLLTRAE
                     GWPYHSGLHVFESDGPLILLDNRSPDEREAHLNDHPFLRRWYARDNRYIYSFDGAQLW
                     RYRTADPKQVRLIWKEQHSGYGYGVNYKTGYLDGKITDDGEFIPAPRNEATK"
     gene            11372..12697
                     /locus_tag="ACHY1N_002043"
     CDS             11372..12697
                     /locus_tag="ACHY1N_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001584058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DKNYY family protein"
                     /protein_id="HFS4044363.1"
                     /translation="MKGQIITVALILLGHTFLTPAVQAIGFDYYNDHGVMSYGKGYWG
                     DKKIIAQFPKMNRADLRLVTNISGERELVEGYIPTDEISIKNEEYHWVTDGRVILWRG
                     KIVSNPPGTPTVDIASFQAMGRFAVDKYSLYFDGQRTESNSGASRVDLATLKAIEGNS
                     TTLVDSKNLYLSGRRQGSSSNVTVLEKRWWGINPRLMSVNRNLYSNDLLIRSGQNIYL
                     NGVHLTANADSFEIIRWIPHSLLVFRDNKGMHRYPFGQLSGKAIPVDDDVSFEVGESR
                     VRWRKQLTSDRQWSKWIDLPDIEPEQFHLITGNIAQYKDRLYVTKLSTFGEDQLEIIP
                     LDTPDLVIDRSFNSGKQHAYFIRQLRSKSVQIIPVNGPLTKNDRFAYDDRNVYTWTDT
                     EVRITPSPCPAKTHVREENVRELHNRDIIIPLTDDSCRNAATDGQTLKP"
     gene            12745..13065
                     /gene="cyaY"
                     /locus_tag="ACHY1N_002044"
     CDS             12745..13065
                     /gene="cyaY"
                     /locus_tag="ACHY1N_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HFS4044364.1"
                     /translation="MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGET
                     VSFR"
     gene            complement(13105..15651)
                     /gene="cyaA"
                     /locus_tag="ACHY1N_002045"
     CDS             complement(13105..15651)
                     /gene="cyaA"
                     /locus_tag="ACHY1N_002045"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HFS4044365.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLESWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC
                     EKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLY
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEG
                     IIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQYFS"
     gene            16038..16979
                     /gene="hemC"
                     /locus_tag="ACHY1N_002046"
     CDS             16038..16979
                     /gene="hemC"
                     /locus_tag="ACHY1N_002046"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HFS4044366.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICERE
                     DPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
                     NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAA
                     LNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGER
                     RGAPQNAEQMGISLAEELLNNGAREILAEVYNGDAPA"
     gene            16976..17716
                     /gene="hemD"
                     /locus_tag="ACHY1N_002047"
     CDS             16976..17716
                     /gene="hemD"
                     /locus_tag="ACHY1N_002047"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HFS4044367.1"
                     /translation="MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGRQLPQLA
                     DQLAALGESDLLFALSQHAVAFAQSQLHQQDRKWPRLPDYFAIGRTTALALHTVSGQK
                     ILYPQDREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTARGAEVTFCECYQR
                     CAIHYDGAEEAMRWQSREVTMVVVTSGEMLQQLWSLIPQWYREHWLLHCRLLVVSERL
                     AKLARELGWQDIKVADNADNDALLRALQ"
     gene            17738..18937
                     /gene="hemX"
                     /locus_tag="ACHY1N_002048"
     CDS             17738..18937
                     /gene="hemX"
                     /locus_tag="ACHY1N_002048"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HFS4044368.1"
                     /translation="MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAI
                     AIALAAGVGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKAELEGIIKQQAAQLK
                     QANRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
                     LLKSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYDGIILKLNQLSNQVDNLRL
                     ADNDSDGSPMDSDGEELSSSISEWRINLQKSWQNFMDNFIAIRRRDDTAVPLLAPNQD
                     IYLRENIRSRLLVAAQAVPRHQEETYRQALENVSTWVRAYYDTDDATTKAFLDEVDQL
                     SQQNISMDLPETLQSQAMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPAPAPAPQGDTP
                     AAAPQGE"
     gene            18940..20136
                     /gene="hemY"
                     /locus_tag="ACHY1N_002049"
     CDS             18940..20136
                     /gene="hemY"
                     /locus_tag="ACHY1N_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0042168 - heme metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HFS4044369.1"
                     /translation="MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKAHV
                     GDEEHRAMLEQQAWIGLMDQARADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTL
                     GQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTL
                     QNNPPQ"
     gene            20814..20951
                     /locus_tag="ACHY1N_002050"
                     /pseudo
     CDS             20814..20951
                     /locus_tag="ACHY1N_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312758.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
     gene            complement(21059..22294)
                     /gene="aslB"
                     /locus_tag="ACHY1N_002051"
     CDS             complement(21059..22294)
                     /gene="aslB"
                     /locus_tag="ACHY1N_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0018209 - peptidyl-serine modification
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HFS4044370.1"
                     /translation="MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTH
                     MDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLGLDFYRRAVKLQAKYGAGRKISN
                     SFQTNGVLLDDKWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
                     QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETAASDGLKLH
                     APGDIQGELTEWSVRPDEFGEFLVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVC
                     HHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMIDSPQQQVFGEDKFKQ
                     LPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLL
                     AHGRPASDIMQAHLLVVNK"
     gene            complement(22441..22517)
                     /locus_tag="ACHY1N_002052"
     tRNA            complement(22441..22517)
                     /locus_tag="ACHY1N_002052"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22481..22483),aa:Pro,seq:tgg)
     gene            complement(22560..22646)
                     /locus_tag="ACHY1N_002053"
     tRNA            complement(22560..22646)
                     /locus_tag="ACHY1N_002053"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22610..22612),aa:Leu,seq:cag)
     gene            complement(22667..22742)
                     /locus_tag="ACHY1N_002054"
     tRNA            complement(22667..22742)
                     /locus_tag="ACHY1N_002054"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22707..22709),aa:His,seq:gtg)
     gene            complement(22801..22877)
                     /locus_tag="ACHY1N_002055"
     tRNA            complement(22801..22877)
                     /locus_tag="ACHY1N_002055"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22841..22843),aa:Arg,seq:ccg)
     gene            complement(22980..24365)
                     /gene="yifK"
                     /locus_tag="ACHY1N_002056"
     CDS             complement(22980..24365)
                     /gene="yifK"
                     /locus_tag="ACHY1N_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4044371.1"
                     /translation="MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVA
                     GVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAA
                     IASHPFRSILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGL
                     NRHGKAHKLEE"
     gene            complement(24556..25296)
                     /gene="wecG"
                     /locus_tag="ACHY1N_002057"
     CDS             complement(24556..25296)
                     /gene="wecG"
                     /locus_tag="ACHY1N_002057"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047241 - lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HFS4044372.1"
                     /translation="MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAI
                     NAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMA
                     RAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASG
                     AQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWL
                     YRLLSQPSRIKRQLRLLRYLRWHYTGNL"
     gene            complement(25299..26651)
                     /gene="wzyE"
                     /locus_tag="ACHY1N_002058"
     CDS             complement(25299..26651)
                     /gene="wzyE"
                     /locus_tag="ACHY1N_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECA oligosaccharide polymerase"
                     /protein_id="HFS4044373.1"
                     /translation="MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPR
                     RPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
                     "
     gene            complement(26648..27727)
                     /gene="rffT"
                     /locus_tag="ACHY1N_002059"
                     /gene_synonym="wecF"
     CDS             complement(26648..27727)
                     /gene="rffT"
                     /locus_tag="ACHY1N_002059"
                     /gene_synonym="wecF"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HFS4044374.1"
                     /translation="MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDD
                     GLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPS
                     QFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFAARGDLSFFAKTHPKVRGEL
                     LYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNDHIAALCAVHQQFGDTVKVVVP
                     MGYPPNNEAYIEEVRQAGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQG
                     IGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKN
                     TIAFFSPNYLQGWQRALAIAAGEVA"
     gene            complement(27724..28974)
                     /gene="wzxE"
                     /locus_tag="ACHY1N_002060"
     CDS             complement(27724..28974)
                     /gene="wzxE"
                     /locus_tag="ACHY1N_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HFS4044375.1"
                     /translation="MSLAKASLWTAASTLVKIGAGLLVGKLLAVSFGPAGLGLAANFR
                     QLITVLGVLAGAGIFNGVTKYVAQYHDNPQQLRRVVGTSSAMVLGFSTLMALVFVLAA
                     APISQGLFGNTDYQGLVRLVALVQMGIAWGNLLLALMKGFRDAAGNALSLIVGSLIGV
                     LAYYVSYRLGGYEGALLGLALIPALVVIPAAIMLIKRGVIPLSYLKPSWDNGLAGQLS
                     KFTLMALITSVTLPVAYIMMRKLLAAQYSWDEVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKRDITREVVKSLKFVLPAVAAASFTVWLLRDFAIWLLLSNKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEISQFTLLMVFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(28976..30106)
                     /gene="rffA"
                     /locus_tag="ACHY1N_002061"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(28976..30106)
                     /gene="rffA"
                     /locus_tag="ACHY1N_002061"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019180 -
                     dTDP-4-amino-4,6-dideoxygalactose transaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HFS4044376.1"
                     /translation="MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRP
                     DTMNIDETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGR
                     IELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLHGCPAGERFG
                     EFHGEDRYTTKESERLLRLPLFYNLSPVNQRTVIATLLNYFS"
     gene            complement(30111..30785)
                     /gene="rffC"
                     /locus_tag="ACHY1N_002062"
                     /gene_synonym="wecD"
     CDS             complement(30111..30785)
                     /gene="rffC"
                     /locus_tag="ACHY1N_002062"
                     /gene_synonym="wecD"
                     /EC_number="2.3.1.210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxy-D-galactose
                     acyltransferase"
                     /protein_id="HFS4044377.1"
                     /translation="MPVRASIEPLTWENAFFGVNSAIVRITSEAPLLTPDVLAPWSRV
                     QAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNVSDSGAVVAQETDIPALRQLASA
                     AFAQSRFRAPWYAPDASRRFYAQWIENAVRGTFDHQCLILRAASGGIRGYVSLRELNA
                     TDARIGLLAGRGVGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVEST
                     AYWLYR"
     gene            complement(30763..31644)
                     /gene="rfbA"
                     /locus_tag="ACHY1N_002063"
     CDS             complement(30763..31644)
                     /gene="rfbA"
                     /locus_tag="ACHY1N_002063"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFS4044378.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT
                     GYGQYLLELLRARPRQY"
     gene            complement(31663..32730)
                     /gene="rffG"
                     /locus_tag="ACHY1N_002064"
     CDS             complement(31663..32730)
                     /gene="rffG"
                     /locus_tag="ACHY1N_002064"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFS4044379.1"
                     /translation="MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSL
                     APVAQSEHFAFEKVDICDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWNTLTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKPLPVYG
                     NGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPN
                     KPHGVVHYRDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLAN
                     ESWWKQVQDGSYQGERLGLKG"
     gene            complement(32730..33992)
                     /gene="wecC"
                     /locus_tag="ACHY1N_002065"
     CDS             complement(32730..33992)
                     /gene="wecC"
                     /locus_tag="ACHY1N_002065"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0089714 - UDP-N-acetyl-D-mannosamine
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HFS4044380.1"
                     /translation="MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWLIAVPTPFKGDHEPDMTYVESAA
                     RSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSTRASELYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICADQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNI
                     DDLRESPAMEIAELIAQWHSGETLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVM
                     LVDHSQFKVINGDNVHQQYVVDAKGVWR"
     gene            complement(33989..35119)
                     /gene="wecB"
                     /locus_tag="ACHY1N_002066"
     CDS             complement(33989..35119)
                     /gene="wecB"
                     /locus_tag="ACHY1N_002066"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312746.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HFS4044381.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLD
                     QVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLREN
                     VADSRIFITGNTVIDALLWVRDQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESF
                     GRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVE
                     EVTRLLKDENEYQTMSRAHNPYGDGQACSRILEALKNNRISL"
     gene            complement(35175..36221)
                     /gene="wzzE"
                     /locus_tag="ACHY1N_002067"
     CDS             complement(35175..36221)
                     /gene="wzzE"
                     /locus_tag="ACHY1N_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HFS4044382.1"
                     /translation="MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIA
                     LAYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDARSNMASADQPSVMDEAYK
                     EFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDS
                     VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKA
                     IYDRRMNSIEQALKIAEQHNISRSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGP
                     AFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGG
                     LIGAGVALTRRCSK"
     gene            complement(36233..37336)
                     /gene="wecA"
                     /locus_tag="ACHY1N_002068"
     CDS             complement(36233..37336)
                     /gene="wecA"
                     /locus_tag="ACHY1N_002068"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009276 - Gram-negative-bacterium-type
                     cell wall [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0036380 -
                     UDP-N-acetylglucosamine-undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HFS4044383.1"
                     /translation="MNLLTVSTDLISIFLFTTLFLFFARKVAKKVGLVDKPNFRKRHQ
                     GLIPLVGGISVYAGICFTFGIVDYYIPHASLYLACAGVLVFIGALDDRFDISVKIRAT
                     IQAAVGIVMMVFGKLYLSSLGYIFGSWEMVLGPFGYFLTLFAVWAAINAFNMVDGIDG
                     LLGGLSCVSFAAIGMILWFDGQTSLAIWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWILLETTQGKTHPISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLIMRAGFTSRQAFVLITLAAALLASIGVLAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRNRGGSPNLTK"
     gene            complement(37576..38835)
                     /gene="rho"
                     /locus_tag="ACHY1N_002069"
     CDS             complement(37576..38835)
                     /gene="rho"
                     /locus_tag="ACHY1N_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017492510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFS4044384.1"
                     /translation="MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(38920..39021)
                     /gene="rhoL"
                     /locus_tag="ACHY1N_002070"
     CDS             complement(38920..39021)
                     /gene="rhoL"
                     /locus_tag="ACHY1N_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide RhoL"
                     /protein_id="HFS4044385.1"
                     /translation="MRSEQISGSSLNPSCRFSSAYSPVTRQRKDMSR"
     gene            complement(39162..39491)
                     /gene="trxA"
                     /locus_tag="ACHY1N_002071"
     CDS             complement(39162..39491)
                     /gene="trxA"
                     /locus_tag="ACHY1N_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA];
                     GO_process: GO:0006662 - glycerol ether metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HFS4044386.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            39622..40887
                     /gene="rhlB"
                     /locus_tag="ACHY1N_002072"
     CDS             39622..40887
                     /gene="rhlB"
                     /locus_tag="ACHY1N_002072"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HFS4044387.1"
                     /translation="MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEY
                     IEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTD
                     LPKPLRLTRPRTGNGPRRTGAPRNRRRSG"
     gene            41021..42505
                     /gene="gppA"
                     /locus_tag="ACHY1N_002073"
     CDS             41021..42505
                     /gene="gppA"
                     /locus_tag="ACHY1N_002073"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008894 -
                     guanosine-5'-triphosphate,3'-diphosphate diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0015974 - guanosine pentaphosphate
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HFS4044388.1"
                     /translation="MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAA
                     GLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQE
                     ILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSL
                     SMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQAL
                     QEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIF
                     TELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVA
                     ANFFDQVEKEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPA
                     QKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMT
                     LQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWPLEVH"
     gene            complement(42552..44573)
                     /gene="rep"
                     /locus_tag="ACHY1N_002074"
     CDS             complement(42552..44573)
                     /gene="rep"
                     /locus_tag="ACHY1N_002074"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HFS4044389.1"
                     /translation="MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     ANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAEAKGER
                     DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALTVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGTELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGY
                     EALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFP
                     YVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK"
     gene            44790..45239
                     /locus_tag="ACHY1N_002075"
     CDS             44790..45239
                     /locus_tag="ACHY1N_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFS4044390.1"
                     /translation="MAINFSPKVGEIQECNFGNYPVIQNGQFSTTYYDGRIPPEMIKN
                     RLVVVLNGKINGNACIVVPLSTTRDHDKLNRGMHVEIASNVINVLQFFDQQIRWAKAD
                     LVQQVSRNRLNRARTYRGYLNQCLPHELVADIQRAVIKSINAISLIN"
     gene            45438..45719
                     /gene="ppiC"
                     /locus_tag="ACHY1N_002076"
     CDS             45438..45719
                     /gene="ppiC"
                     /locus_tag="ACHY1N_002076"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004097481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HFS4044391.1"
                     /translation="MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSG
                     KRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN"
     gene            complement(45806..47281)
                     /gene="ilvC"
                     /locus_tag="ACHY1N_002077"
     CDS             complement(45806..47281)
                     /gene="ilvC"
                     /locus_tag="ACHY1N_002077"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004455 - ketol-acid reductoisomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HFS4044392.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     VNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
                     GAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            47431..48324
                     /gene="ilvY"
                     /locus_tag="ACHY1N_002078"
     CDS             47431..48324
                     /gene="ilvY"
                     /locus_tag="ACHY1N_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HFS4044393.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLG
                     QPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTIDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGKADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPALPCPVRNQVSVEKPDWSTVPFIMADQGPVRRRIELWFRRNKISNPM
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILDRSDEKTPFELGVCA
                     QKKRLHEPLIEAFWRILPNHK"
     gene            complement(48376..49920)
                     /gene="ilvA"
                     /locus_tag="ACHY1N_002079"
     CDS             complement(48376..49920)
                     /gene="ilvA"
                     /locus_tag="ACHY1N_002079"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HFS4044394.1"
                     /translation="MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIAQHNIRGERLAHILSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEER
                     KEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRF
                     LNTLGTHWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAF
                     RFFLAG"
     gene            complement(49923..51773)
                     /gene="ilvD"
                     /locus_tag="ACHY1N_002080"
     CDS             complement(49923..51773)
                     /gene="ilvD"
                     /locus_tag="ACHY1N_002080"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HFS4044395.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIG
                     ILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFS
                     QDCRWDSLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELA
                     ARREAQEARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG"
     gene            complement(51838..52767)
                     /gene="ilvE"
                     /locus_tag="ACHY1N_002081"
     CDS             complement(51838..52767)
                     /gene="ilvE"
                     /locus_tag="ACHY1N_002081"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HFS4044396.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLIF
                     VGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIDVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ"
     gene            complement(52787..53050)
                     /gene="ilvM"
                     /locus_tag="ACHY1N_002082"
     CDS             complement(52787..53050)
                     /gene="ilvM"
                     /locus_tag="ACHY1N_002082"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HFS4044397.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQN
                     INIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA"
     gene            complement(53047..54693)
                     /gene="ilvG"
                     /locus_tag="ACHY1N_002083"
     CDS             complement(53047..54693)
                     /gene="ilvG"
                     /locus_tag="ACHY1N_002083"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HFS4044398.1"
                     /translation="MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLC
                     RHEQGAAMAAIGYARATGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVSAP
                     FIGTDAFQEVDVLGLSLACTKHSFLVQSLEELPRIMAEAFDVASSGRPGPVLVDIPKD
                     IQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPMLYVGGGVGMAQAVPALRE
                     FLATTKMPATCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPHASVIHMDIDPAEMNKLRQAHVALQGDLNALLPALQQPLNINDWQLHC
                     AQLRDEHAWRYDHPGDAIYAPLLLKQLSDRKPADCVVTTDVGQHQMWAAQHIAHTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIPGQHITRKDQVEAAL
                     DTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(54696..54746)
                     /gene="ilvX"
                     /locus_tag="ACHY1N_002084"
     CDS             complement(54696..54746)
                     /gene="ilvX"
                     /locus_tag="ACHY1N_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide IlvX"
                     /protein_id="HFS4044399.1"
                     /translation="MNNSTKFCFSRFRTGN"
     gene            complement(54833..54931)
                     /gene="ilvL"
                     /locus_tag="ACHY1N_002085"
     CDS             complement(54833..54931)
                     /gene="ilvL"
                     /locus_tag="ACHY1N_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HFS4044400.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
     gene            55285..56805
                     /gene="yifB"
                     /locus_tag="ACHY1N_002086"
     CDS             55285..56805
                     /gene="yifB"
                     /locus_tag="ACHY1N_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HFS4044401.1"
                     /translation="MSLSIVHTRAALGVNAPPITVEVHISKGLPGLTMVGLPETTVKE
                     ARDRVRSAIINSGYEYPAKKITINLAPADLPKEGGRYDLPIAIALLAASEQLTANKLD
                     EYELVGELALTGALRGVPGAISSATEAIKSGRKIIVAKDNEDEVGLINGEGCLIADHL
                     QAVCAFLEGKHALERPKPTDAVSRALQHDLSDVVGQEQGKRGLEITAAGGHNLLLIGP
                     PGTGKTMLASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSASLT
                     AMVGGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITY
                     PARFQLVAAMNPSPTGHYQGNHNRCTPEQTLRYLNRLSGPFLDRFDLSLEIPLPPPGI
                     LSKTVVPGESSATVKQRVMAARERQFKRQNKLNAWLDSPEIRQFCKLESEDAMWLEGT
                     LIHLGLSIRAWQRLLKVARTIADIDQSDIITRQHLQEAVSYRAIDRLLIHLQKLLT"
     gene            complement(56830..57168)
                     /gene="maoP"
                     /locus_tag="ACHY1N_002087"
     CDS             complement(56830..57168)
                     /gene="maoP"
                     /locus_tag="ACHY1N_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HFS4044402.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGYAFNE
                     LDLGKREPVTEEEKLFVAVCRGEREPVTEAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTDSDD"
     gene            57287..58126
                     /gene="hdfR"
                     /locus_tag="ACHY1N_002088"
     CDS             57287..58126
                     /gene="hdfR"
                     /locus_tag="ACHY1N_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HFS4044403.1"
                     /translation="MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLG
                     VNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWEC
                     MLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
                     LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQ
                     IAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNTLIRDLLKINVLD
                     EVY"
     gene            complement(58222..58297)
                     /locus_tag="ACHY1N_002089"
     tRNA            complement(58222..58297)
                     /locus_tag="ACHY1N_002089"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58262..58264),aa:Trp,seq:cca)
BASE COUNT        14390 a        15580 c        14741 g        13592 t
ORIGIN      
        1 tatttcagct caaaaaatat ctcttttaag ttttcaaaac tacgctatag gatggagtgc
       61 aacaattcat tttgtagcac aggaccactt cggtcttgat gtaactgata tcaaaaacaa
      121 gacttacagc aaatatagat tttttcgcat atggttcttt ttacaacggc ataaagactt
      181 tgctttcaaa ccttttttca ccaattttaa cactatcgaa agaatcgaaa attatctatg
      241 aaaagcaaac tccagaaaat tatattatgt ttatttcttc tatgctgcat ctataattta
      301 tggacattgc gtcctgtaca gattttgtat acatactctg atgctggcaa ttcagtcttt
      361 ctggtcgttg atcatctgcc atggactgac agcgataaaa taaattggta tctgaagcat
      421 cagaatgaaa ttaaaaatca acatccccta ccagaaggta gttggcatac ctggtatgtc
      481 attgatatcg gtaatggctt cactgactat aaaaaatata tcgaagggcc gtatgaagat
      541 ctctactgtt tcccgacaat taagagcaat gataattgca tcgtgaaaaa ttacttaatg
      601 gttattaatg aataccctta tcgtaacact catattggta ttaacgattt tactgagtat
      661 caattaacac aagaaaataa aatagagcga gttttcaatc cgcatgactt taaaaaagac
      721 aatttttaga aataagccgg ataaaaaaat agctttatcc ggcactcata ttacaaccag
      781 ttcttccgct taaagtacag atacggtgcc aggcccgcga ggatcataaa gataatcgcg
      841 cctgggtagc cgaaactcca cttcaactct ggcataaatt caaagttcat cccgtagctg
      901 gaagccacca gcgtcggtgg caggaacacc acggatacca ccgagaagat tttgatgatg
      961 cggttctgct cgatgttgat aaagcccatc gccgcctgca tcaggaagtt caccttctgg
     1021 aacagggatt cgttatgcgg cagcagggat tcgatatctc gcaggatttc acgcgcctgc
     1081 tccagttgcc cacccggtaa acgcgccttg cgtaccagga agttgagcgc gcgctgggta
     1141 tccatcagac acaggcgaac tttccagccg atatcttcca gttccgccag cgtggagagc
     1201 gcctcgtcgt actcatcgcc ctgatgccct tccataatca cccggctcaa ctgctccagg
     1261 tcgctataga tattttcaat ttcatctgcc aactgttcga ttttggtttc gaacagatcc
     1321 agcagcaact cgtaggcgtt accgtctacc atcgactggc tacgggcacg catacgatac
     1381 agacgaaaag cgggcagttc acgctcacgc agagtaaaca gacgaccatc acggatggta
     1441 aatgccacag tggagttacc ggcgtgatct tccgcatctt caaagaagaa gaaggagtga
     1501 atatgcaggc cgtcgtcgtc ttcaaagaaa cgtgccgatg cttcgatgtc ttccagttcc
     1561 gggcgggttg ccaggctctg gccaagttca gattgtacgc gcagtcgctc gtcgtcgtcc
     1621 ggttcgacaa gatcaatcca tactgcattt acaaggggtt gtgactcttc gacttccagc
     1681 cgggtcagtc ggttattttc cagttgaaat gcgctcagca tgaccgggac tcccaatgct
     1741 taaaatatcg gacagttcgg tgggcacaca gaaacaaatt gggtttcaga ccattaaaca
     1801 gcctgactca gcgcgacggg aaaaattgag gtcgctgaca accgctaagg ctatcagcaa
     1861 aaagggatag ccttaggagt tgatcctgga tgacaggata gtgagccagt atctactggg
     1921 tgtgtccaag gcgaatgtcc tcttagagtg atcgtgcgcg catgttacgc cagcaaaatt
     1981 ttgccgtcaa cacgcaacag aacaccacag aacaatagtt gaacttcgcg ctttttggta
     2041 ctcgtcaagg tcgctaacag gataaaaaaa tccaacatcc aggacctata atggcgcatc
     2101 ggctactcat tggtaaagga atgatcacct tgaatctcaa acggattttt ctcaccctca
     2161 ccttacttcc cttgtttgct gttgccgctg atgattgcgc actctcagat ccgacgctga
     2221 ccgtacaggc gtataccgtt aatcctcaaa cagagcgggt gaaaatgtac tggcaaaaag
     2281 ctaatggcga agcgtgggga acgttacatg ctctgctggc ggatatgaat agtcagggtc
     2341 aggtgcagat ggcgatgaac ggcggcatct atgatgaaag ctatgcgccg ctcggtttgt
     2401 acatcgaaaa cggtcagcag aaggtggcgt taaatctcgc ttcaggtgaa gggaatttct
     2461 ttatccgtcc tggcggcgtg ttttatgtcg cgggagataa agtcggcatc gttcgtctgg
     2521 atgccttcaa aaccagtaaa gagattcagt ttgcggtgca gtcagggcca atgttgatgg
     2581 aaaacggtgt aattaatccg cgtattcatc ccaacgtcgc ctcacgcaaa attcgtaacg
     2641 gtgttgggat taataaacat gggaatgccg tgtttttgtt gagccagcag gcgacaaatt
     2701 tttatgattt tgcctgttat gccaaagcga aactgaacgt tgagcagctg ctttatcttg
     2761 atggcacgat ttcacatatg tatatgaaag gcggggcaat cccgtggcaa cgctatcctt
     2821 ttgtcaccat gatttccgtc gagcggaaag gttagaatga tagttttgtg tcagatacta
     2881 aatatgctgc tgatgccgga tgcggcgtaa acgccttatc cggcctacat gacgttgcaa
     2941 tttattgaat ctgaatgatt ttttaggcca aataaggtgc gcagcaccgc atccggcaac
     3001 gttacaccga ctccagccgg gcataagccg ccaccagcca tttaataccc tggccctgaa
     3061 atgccacctg caaacggcta tgctcaccgc tgccttccat attgacaatg gtgccttcac
     3121 caaacttagc gtggcgtacg cgctggccga gcttgtagcc gctgtcgttc tcgaccatcg
     3181 gcgtacccat ccgctgatgg ctgaccgggc ggcttaccgt ggcgcgcagg cgcacctctt
     3241 ccacacactc ttccggcagc tcgccaataa agcgcgacgg gcgatggtaa acctctttgc
     3301 catacagacg gcgagtttcc gcgtaggtca gcgtcagttt ctgcatcgcg cgggttacgc
     3361 caacgtaggc cagacggcgt tcttcttcca gacgcccgcc ttcatccagc gacatctggc
     3421 ttgggaacat accctcttcc ataccgacaa taaacacctg cgggaactcc aggcctttcg
     3481 ccgagtgcag cgtcatcaac tgcactgcat cctgccaggt atccgcctgc ccctcgcccg
     3541 cttccagcgc cgcatgggag aggaatgcct gcagcggcat taaatcttca tcttcttcgt
     3601 tgtagctgaa ctggcgcgtt gccgtcacca gttcctctaa gttttcgata cgcgtctggc
     3661 ctttttcgcc cttctcctgc tcgtacatgg tgcgcaggcc ggagtcttta attacccggt
     3721 cagtctgtac atgcagcggc atatcggcag tttcttgcgc taaggcatcg attaattcca
     3781 taaatcgctg caaggcgctg gcagctcgcc cggcgagggc tttttcctgc aacagttcac
     3841 gacatgcctg ccagagtgtt aactggcgat cgcgcgatgt ctgacgtacc acgtccagcg
     3901 tccggtcacc aataccccgc gttggcgtat tcaccacgcg ctcaaacgcc gcgtcgtcgt
     3961 tacggttggc aatcagacgc agatacgaga gcgcgtcttt gatttcctgg cgttcgaaga
     4021 agcgcatccc gccgtaaata cggtacggca tactggcctg caacagtgct tcttccagta
     4081 cacgcgactg ggcgttactg cggtagagaa tggcgcactc ggcaagcgcc ccgccgttgt
     4141 cctgccaggt tttgatgcgg ttaaccacaa aacgcgcttc atcgagttcg ttaaaagcgc
     4201 aatagaggga aataggctca ccgtccgcgc catcggtcca cagtttttta cccagacgcc
     4261 cgttattgtt ttcaatcagg gcgttagcgg cgctcagaat attgctggta gagcggtagt
     4321 tttgctccag acgaatagtt tcggcaccgg ggaaatcatt aaggaaacgc tgaatattct
     4381 ccacctgcgc cccgcgccag ccgtagattg actggtcgtc atcaccgacg atcatcactt
     4441 tgccggtgtc gcccgccagc aggcggatcc acgcgtactg aatgttgttg gtatcctgga
     4501 attcgtccac caggatattg gtaaaacgtt cgcggtagtg ttgtaggata tgcggcttgt
     4561 taagccacag ttcgtgagcg cgcagcagca gctcggcgaa gtccaccagg cccgcgcggt
     4621 cacacgcttc ctgatacgcc tgatacacct tctgccaggt ctgctccacc ggattaccgt
     4681 agctttgaat atgatgcgga cgcaggcctt catctttctg gctgttgatg taccacattg
     4741 cctggcgcgg cggccactgc ttctcgtcga ggttcatggc tttgatcaga cgcttaagca
     4801 ggcgcagctg gtcctcgcta tcgaggatct ggaaatcctg cggcagattg gcgtccatat
     4861 ggtgcgcacg cagcaggcgg tgcgccagcc cgtggaaggt gccgacccac atgccgccct
     4921 ggctggtgcc catcagttgc ccgatacgat gacgcatctc cgccgccgct ttgttggtaa
     4981 acgtcaccgc cataatcgag tatggcgagc agttttccac gctcatcagc caggcgatac
     5041 gatgcaccag tacgcgcgtc ttaccactgc ccgcgcccgc cagcaccaga aggttgctgc
     5101 gtggcgcggc caccgcttcg cgctgtttgt cattaaggct gtcgagcagg taagaaacgt
     5161 ccattggcac cgccgcgtaa aaataggttg ggcggagaag cgcaacgccc tccgccaaaa
     5221 agctgggtat atatacagat ttgctgatta tatcagcgag gtcagagatg ccaaccggga
     5281 aatttccaga tgcggcagta aacggctgtc ccaggtttgc atcagatcgc cattttccgg
     5341 tctgatccaa caagcctgca ttccgctgcg aattgcccca cccacgtcag tggtgagatc
     5401 gtccccaaca tgtaagatct cgccgatcgg cacgttgagt ttttccgcag ccaaaaagta
     5461 catatcgctg aacggttttg agcgcccgtg cgggccagcg cgcagcacaa actcaaaata
     5521 atcccccaaa ccaaacagtt ccggctgggc gttaccgttg gtgatcgcca ccagcggcca
     5581 tttcttcgcc agctgtttta aggtgtcgtg agtttgctgc gggacgtcga ttcggctgcg
     5641 ccatttggca aagttaatca ttgctgcgtg tgcgcctgca ctggcttctt cggcactcag
     5701 cccggcgtcg agcatcgctt gttcaatcga acgaaaacgc caacgcgtca cgtcgtgata
     5761 aatctcgggt tccgcttccc gtaccgcctg gcgcaggcgt tgcagatctt cattctggaa
     5821 gctgcgcagc gccggatgat aattttgcac aaaggtaagc gcctctcgct cggtgcgcaa
     5881 aatcaccgga cggttatcgt aaagggtatc atccaggtca aaggtgagcg ccgagatgcg
     5941 ccccaaaggc cggtaaaaac gcattatttc ccccgtttgg cgcgtggatg cgccgcatcg
     6001 tacaccgagg caaggtgttg aaaatcaaga tgagtataga tttgcgtggt ggagaggttg
     6061 gcatgaccca gcagctcctg cacaccacga agatcgccgc tcgactccag catatgcgta
     6121 gcgaacgagt gacgtaattt atgtgggtga acgtgattat tcagcccttg ttttatgccc
     6181 cattcggcaa agcgtttctg cacattacgc gcggagatac gcttgcccag tttcgacaga
     6241 aaaagcgcgt cgtcttcgct accaaacagg tcgcgcaaat caagccagtg ctcaatccac
     6301 gccacagcgt tgcgaccaat cggcaggcgg cgctctttgc tgcctttccc cattacccac
     6361 acttcaccag actccaggtc gaggtgtttg atatccagcc ccaccagctc ggaaagacgc
     6421 agacccgcgc cgtacatcac ttccagcatt gcacggtcgc gtacagcgag gggatcgttg
     6481 atatcaatat ccagcagccg attcatatcg tcgacgtcga tgtttttcgg cagatgacgc
     6541 ggcgctttcg gtgccgaaac tcctttcgcc gggttagctt tgagttcgtt ctggctgacc
     6601 agccagtcaa aaaagctacg tagcgcagaa agccgtaacg ccagacttgc tgctcccagc
     6661 cctttacggc gactgcgtac agcaaaattg cgcaccatcg tcacatcaca ttgctgccag
     6721 ctttgcaggc cgttttcgct ggcaaaattg atgatcgcct caagctgacg ctggtagtta
     6781 agcagggtta tcgggctaag ctggcgctcc acgctcagat aacgtaggta gcgttctaca
     6841 tcggtgtgta aatcggtcat acgcgttcaa tccaacgctc cagaagctcc ggcaacatca
     6901 gcgcaatttc atgaagtaac tgcgttcctt gcccttgttg atagtgactg gcatcgcgac
     6961 tggtaaacag cacaacaccc aaatcagcat cgcttcccag catcgacatc gccaccgatc
     7021 ccaccgcttt cgcttccggt agcaccacca gcaactctgg tccgttaagc ggcccaagat
     7081 agtgctgttc ctgccccaaa cgctgaatac gcagcggttc gaaagactga cggcttaatg
     7141 ccagatgagt gtggttcgac ggcgcaccta agcgccagcg atccggaaac aggcgcagac
     7201 tcgcacctgc caggccgaga tcgcgcgccc agcggtgaaa gcgcatcagc atatcgtcga
     7261 gactgctggc ggcggtgaga ctgcgctgca ggtagagtag gcgataaaac aggccttcgt
     7321 tggcgatagc ctgttccatc aacagcgcca tgttctcttc cagaacatga atatgattac
     7381 gtgcgcgggc catgtgccac tcgaccaacg aaacggtgcc gcgtaccgga tgcggcacac
     7441 gtatcgcttc tactgcgcgc gcattacgga taaaaaactc aggattttta atcagataat
     7501 cgacaaccgc ccggtcatca agctccgtga gtgtttcctg cagttcttcc cctggttgct
     7561 tcatagatga ataaatccgt cgtagacatg taccgccggg ccagtcatat ataacgggtg
     7621 acccggacct ttccaggcga tatcaagacg accgccgggg agttccacgc gtacttcttc
     7681 ggccagcaaa ccttgctgaa tccctaccgc caccgccgca catgcgccgc tgccgcaggc
     7741 ctgggtttct cctgccccac gctcataaac gcgtaaacga atatgctcgc gcttaaccac
     7801 ttgcataaaa ccgatattgg ctcgctccgg aaaacgctcg tggctttcca gaacaggacc
     7861 aagcgtttct accgccgcgg tatcgacatc atcgacctga atcacgcaat gcggatttcc
     7921 catcgacacc acgccgcata agattgtctg ctcggcggcg cgcataatat aggtcttttc
     7981 cgctttgtta gcgcgaaacg gcacggcgga aggttcgaag ttgggttcgc ccatatttac
     8041 gcggaccaga tcatcatcgg tgacggtcag aaccatccgc ccgttggcgg tgctgacgcg
     8101 gatatcgcgc ttattggtca gccctttcag acgcacaaaa cgggcaaagc agcgcgcacc
     8161 attgccgcac tgcgccactt cactgccatc agcattgaaa atgcgatagt gaaaatccag
     8221 ttcaggatca tacggcggct caaccaccag cagttggtca aaccctactc ccaggtgccg
     8281 atcagccagg cgacgaatca gctccggtga aaaaaagaca ttctgcgtta ccgcgtcgac
     8341 gaccataaaa tcgttgccaa ggccatgcat tttcgagaac tgcatcattt actccaatca
     8401 cgcgggtaca gaaactgact tttagtaatt cacctgggat ggaccatcgc cagtggcgcg
     8461 atcgttttta tccggcaccg tggattgcgt ttgcgtctct accggtttgg tcggcggcgg
     8521 tgcgttttta tctgcaggcg ggaaatagag cggacctttc agaccgcagc ccgtcaggct
     8581 gaagagagta attaatacag tgagtgcctt aaacacgttt ttcattatgg attgcctgta
     8641 aagttcatcg ctttctgctt tctatcatcg caggagaagg cgtaaaagca agcgtttagc
     8701 gactctttat gaagtctgaa aagtgaggaa atgctgcgag tataacgctt acacgtgggg
     8761 atttatgttt tgctggtagt ttcgtgatcg gcacctcgcg ccaggatggc tttatgcact
     8821 atcgcaatgt ggtttgtttg ttgtcttgtt cattgttctt atcgtcggca tggggctttt
     8881 aatagagtgg cgcaccatgc aatttcgttg tctgacctta gtcgccagtg acatacaact
     8941 ttgccaacct ggtgataaga gggaataaaa tctgatgggg ctatttaccc aactggaaaa
     9001 atttgaccaa aagcttacgc gcggttatgc ccggtggggg cgctgggtat ggcggacgtt
     9061 aattgtcgtt ccggtactgg tcgtgttgtg gaatatagga caggcagtat ggggaggacc
     9121 aagaggtgga gtgattctgg aaatccacag tgaaattgac cgcccgatac tgggattcag
     9181 tgttaacggc gtggcgggcg cgaatgcttt tgcaaatggt ggcggttcaa caacctgttg
     9241 tggtgatgtt agtggggata cggcagaggt tatctggaca ttaagtacta ctcgtacaca
     9301 gtataatgct ggaatgcgtc tggagaaacg gaatatgacg ttacctctcc ccaaaagaga
     9361 atggggagaa gattttctgc atgtgcattt tatgcctggc gataaagtgc tgctggggtg
     9421 gagtaaagat tctttttctc cgtatgaaga tcttcacaac ggggggtaca agacccgcgt
     9481 tcggcaggat gtgaaagata aactttatgg tacagggaaa atgaattgat agatttctat
     9541 aaaaatcacg ttcggcagaa agcgtaataa tgtggggaat gttagatacc ggtggtggga
     9601 cctaagtaca acacgcgaaa gacaataaag taggtaacgg tgggcagagt cgcatgttga
     9661 cacccttccc ggcgtcaatc cggcacattt taacgtgatc agtcacacca tggcgcagta
     9721 gctcgtattt atatcgtgaa tgaaaacctc aagtttaccc cagcaactat cagaaaatag
     9781 cgatggcctt tatagattct gaaaagtgac gatttgccgc aaaagttacg cttacgtgcg
     9841 aggaattatg ttctgctggt agtttcgtga tcggcacctc gcgccaggat ggctttatgc
     9901 actatcgcaa tgtggtttgt ttgttgtctt gttcattgtt tttatcgtcg gcatggggat
     9961 gtcggcttga tccgcctgaa cataatattt accagaaaca gggaaaaggc gtggtatacc
    10021 tgcgccctta taaagaaaca aatctttctc ttcctgacgt gaattacaaa agtttgcgcc
    10081 gtttacccaa tttattaata gacccgacaa cactagacaa atgggataaa gtacctcctc
    10141 tgactgatct gacaaccgac tacctctatg aaggcgcaca ggcctggtat cctcattact
    10201 cctggcatag cgatggtcgc tatatcctct acgcgggtga agttgtgcaa aacccgccag
    10261 acaaacctcc cgtcgatgtc gcctcgttca aggcgtgggg tgattttgcc gcagataaac
    10321 acagtctcta tttcgaaggc aagcgcaccg ataacaatgg cgggggaaat cgcttagata
    10381 tcaaaacact gcatcaggtg gaattccggc ctccctggga tcctgactta ctggggctga
    10441 tattacgtga cgctaatttc ttgtatatca atgggcatcg cctcgcagat cccgatagtt
    10501 tccgtgtgct ggcacaaaag tcatgggatc agcgaggaaa gttttctacc gcgtttaatc
    10561 cctgtgtggc tatgccattt ggcccctggg ataccctggc tcgtacacgg accaaaatcc
    10621 tgatcaacgg cgaacagctt gatgccgacc cggacacctt ttccgtcgtg cgctggatgc
    10681 ccggctcact cttgacctgg cgtgataaaa acgggctgca gcgtaaagtc ctcgacaagg
    10741 aaaatctgga gtgggatgaa gatttaacaa agcactgtct ggatttttct ctgctggaaa
    10801 agaaagtgtt ctggcgtaaa ggacctgctt gtaaacagga agaattaccc ggactcgatc
    10861 cggagcagtt tcaacccatc agtgatgctg tcgcccagta tcaggactcg ctttatacca
    10921 tcatcgaaac agagtctggt gaccgcaagc tggaaatcgt gaaacttgat gatcccaatc
    10981 ttattatcaa caaacgtttc aacgccggga aacgccacgg ctatttactt acgcgtgccg
    11041 aagggtggcc ataccattcc ggtttacatg tgtttgaatc tgacggaccg ctgatcttac
    11101 tggataaccg ttctccggat gaacgcgaag cccatcttaa tgaccatccc tttttgcgca
    11161 gatggtatgc ccgcgataac cgctacattt acagctttga tggcgcgcag ctctggcgat
    11221 accgcaccgc tgatccgaaa caagttcgct taatctggaa ggaacaacat tcgggatatg
    11281 gctatggcgt aaattacaaa acgggatatc tggacggaaa aattactgat gacggcgaat
    11341 ttattcctgc cccgcgcaat gaggcgacaa aatgaagggt caaataatca cagttgcact
    11401 catcctgttg ggacacacat ttctgacgcc tgctgtacag gccatagggt tcgactatta
    11461 caatgatcac ggtgttatgt cttacggtaa aggttattgg ggggataaga aaatcattgc
    11521 ccaatttccg aagatgaaca gagccgattt gcgccttgtg acaaatatat ccggggagcg
    11581 ggagttggtg gaaggctata tacccaccga tgaaataagc ataaaaaatg aggaatacca
    11641 ctgggtgaca gacggccgcg ttattctctg gcgtggcaaa atcgttagca atccaccggg
    11701 aacacccact gtcgatattg ccagctttca ggctatgggc cgcttcgcgg tcgataaata
    11761 tagcctctat tttgacggac agcgcaccga aagtaatagc ggcgcgtcac gtgttgatct
    11821 ggcgacacta aaagctatcg aaggtaactc taccacgctg gtggatagta aaaatctcta
    11881 tttgtccggt cgacgtcagg ggagcagcag taatgttact gtattagaaa aaagatggtg
    11941 gggtattaat ccacgtctta tgagtgtaaa cagaaatttg tattccaatg atctgcttat
    12001 ccgcagtggg cagaatattt atttaaatgg cgttcacctt acggcgaatg cagactcatt
    12061 tgagataatt cgctggatac ctcattcact gctggttttt cgcgacaata agggtatgca
    12121 tcgttatccc tttgggcaat tgtctggcaa agcgataccc gtagatgatg acgtctcttt
    12181 tgaagtaggg gaaagtcgcg ttcgctggcg taaacagctc acgtccgacc gtcagtggag
    12241 caagtggata gacctaccag atattgaacc tgaacaattc catctgatta ctggcaatat
    12301 tgcgcaatat aaagatcggt tgtatgtaac aaaattatcg acatttggtg aagaccagct
    12361 tgagataatc ccgctggata cgccagacct ggtcattgat cgctcattta atagcggcaa
    12421 acagcatgct tattttatcc gccaattacg gtcaaagagc gtgcaaatta ttccagttaa
    12481 cggtccgcta actaaaaacg atcgcttcgc ttatgacgat cgcaatgttt atacatggac
    12541 cgatacagag gtaaggatta cgccctcccc ctgcccggcg aaaacacacg tcagagaaga
    12601 gaatgtgcgt gaacttcaca acagagacat tattattccg ttgacggatg actcatgccg
    12661 gaacgcagca acagacgggc aaactttgaa gccctgaccc cataccgcta tactgccgcc
    12721 atcacttaaa gacaggatac aacaatgaac gacagtgaat ttcatcgcct ggctgatcaa
    12781 ctctggctga ccattgaaga acgcctggac gactgggatg gcgacagcga tatcgactgc
    12841 gaaatcaacg gcggcgtact gaccattacc tttgaaaacg gcagcaaaat cattattaac
    12901 cgccaggagc cgctgcacca ggtgtggctg gcaaccaaac agggcggcta ccattttgac
    12961 ctaaaaggcg atgaatggat ttgcgatcgc agcggcgaaa ccttctggga tttgctggaa
    13021 caggcggcga cacagcaagc gggtgaaaca gtcagtttcc gctaagattg catgccggat
    13081 aagcctcgct ttccggcacg ttcatcacga aaaatattgc tgtaatagcg gcgtatcgtg
    13141 atcctgattg gcaggcggca tgttaccgat agattttgtg cggaacggaa tcacctgttc
    13201 acgaccatca accttcacaa tctgatagaa ctgcggcagg ttgaagttga tgaagcttga
    13261 gccgtaggtg aagcggtcgt gcgatgacga gtagaagcga ctgacgtcac gcaccagttc
    13321 ctctttgctg ccttcgcagt ggtgatacac ctcaacccgg ttgctttcgt cgagaatgta
    13381 gatattaaag ccattctcgt cttgcgtttc ttcgaagaag aactggatga tcccttcact
    13441 agcaaagccg tccaccaccg ccggtaattt gacgtgattg gtttcaacct gcactgacaa
    13501 gccgtgcagt ttgttatgcg aaatagcgcc ataaaactcg atggcgtttt ccagtttttg
    13561 taccgataca ttcaggcgtt cgaagaacaa cccccaggtt tgaccagaaa cgcgcagcgc
    13621 cttgaaacgc ccggtttcct ggcgggtgct ggaaaggcgc agttcaatac actcagaaac
    13681 cagttgctgc acgcgagtac ggattaaccc gcgcagatgc tggctataac agaagacttc
    13741 cacgctatct ggcggtgcgg cgtcctgatg cattttgccg agaatagttt tcagggcttc
    13801 gatcatcgat tgctcgccgt tgaagtgcag cgtacgcact tcgttccacg agttgcggta
    13861 cagcaggtca acgctaccta ccaggcaatt ttgattctcg ccaaagctga agacatccag
    13921 cttacggaaa tcaaaatgca ccacctgatt gcggaacgcc gctgtcgggt catattccag
    13981 gttaacgata atcgccagat ggcggatctc acacgggctg tagagcgcct tcggtgtcgg
    14041 tgcaggtaag cgcagcggga aatggtgcga cacgtcggcg accatctcct gcaacttagg
    14101 caaatcgaca atgccgttac ctttaatata caaacgggtg cgcgaggtca gcaggccgtt
    14161 aaaccatgcc cacgccacca gtttgttcag gtaacggtta tattccagcg gctgatggct
    14221 gatgatcgac tcaatatttg gcgcgcggtt atacagatac caacctgaac ggttagcacg
    14281 gcccggcggc acataaataa aggtcagatt cggttccgag agatcgggtg aaatctgcgg
    14341 gtttaccagc gtcactttac ctggtaatgc ttcaaacgcg gcatacagct tacgcgtcag
    14401 cacgccgata tcctgcggac tggcggagac gctaaggtta ttgcgacgcg caaagcggat
    14461 cagattacgg tagctctgca tcatcgcgtc gagcaactcg ttgtgcgcct cacgcacctg
    14521 atcaatcttc cagttagcgc ggttatcgag cattgccaga cgagcttcgt cccaacccca
    14581 ctcgctcact aactggctca acactgcgcg acgccagcct acgcaggcgc gttcacggct
    14641 gagcttttcg cacactttta aatagaagca gcgacgtact aaatccagac gggtaaaatc
    14701 ttcaatcgcc gtcaggtatt cagtaacacg ctccagcatc atgcagtatg gatcgagacc
    14761 aaacgataca atctcgccgt cgtgcaaacg ctgtttgata tctttcgcca gcagacgtgg
    14821 gttcgggtat tcccaggaat aggcttccag cagcagtgtt ttcagtaccg ctttgtatgg
    14881 ggaatcgata ctcttgtaga gctgccaaag gctggcacca aagtactctt cagcagaaag
    14941 cgagcttaag ccaccgagat ccagccattc atttggcgtc agcacgccct gcgcgtaaag
    15001 cgtcatcaca tagtcgtcgt aatgctcttc ttcgtcgcac ggcaccatat tccacagaat
    15061 acgcttaccg gcgagacgca cggcggtacg ataaaattcg tcaagcagca gtatatgctg
    15121 ggtggagcca caatcttcgc cccccaggct gccgctttca ttatgacgga agcggttttc
    15181 atcaatcagg aagaagctga cttccacacc cagcgaggcg gcccagcttt ccagcagact
    15241 acatttacgt tgtagtaact ggcgctcttc gctatcgagc caggattgat gacagaccca
    15301 gatatccagg tcagaggaac aactttgccc tacggacgag gtgctgccca tggtgtatac
    15361 accagtaatt ggaagctcac ctttcggtgg gtcctgtact gacattccac gatacagttc
    15421 aagctcgttc aggtagtggc gttgagtttc atcaggcgtg taaaggcaaa tgcctttggg
    15481 aacgttacca tcaaggtaac ccggcattag cggatggtga tagtgcaaca atgtcggcag
    15541 tagactgtag acctgttgga atgcaggccc catagcagca agcgcgcgat ccacacgcaa
    15601 ttgatttatg gcatccagtc tctgtttcag agtctcaata tagaggtaca agacgtatcg
    15661 cctgatttgc tacccgtcat gactgtgatt ccgccaacat caacggtaac acgcggcatt
    15721 cgggatattt cgtatgtcaa aggtaaccgt taccactttt cgcgcctggt ttttttagtt
    15781 tcacgacgaa aaaatggtct aaaacgtgat caatttaaca ccttgctgat tgaccgtaaa
    15841 gaaagatgcg ctacatacaa gtgtagcacc gtttattctc tgtaaattcc ttattacgac
    15901 ggcgtgaaac gcctgtcagg atccactgcc agacctcatt ttacggtttg cgcaggcgtc
    15961 tacgtttcac cacaacactg acatcactct ggcaaggatg ttaggatgga ccacggatga
    16021 taatgacggt aacaagcatg ttagacaatg ttttaagaat tgccacacgc caaagcccac
    16081 ttgcactctg gcaggcacac tatgtcaaag acaagttgat ggcgagccat ccgggcctgg
    16141 tggttgaact ggtaccgatg gtgacgcgcg gcgatgtgat tcttgatacg ccgctggcga
    16201 aagtaggcgg aaaaggctta tttgtaaaag agctggaagt cgcgctcctg gagaatcgcg
    16261 ccgatatcgc cgtacattca atgaaagatg tgccggttga attcccgcaa ggtctggggt
    16321 tggtcactat ttgtgagcgt gaagatcctc gcgatgcctt tgtgtccaat aattatgaca
    16381 gtctggatgc gttaccggca ggcagtatcg tcgggacgtc cagtttacgt cgccagtgcc
    16441 aactggctga acgccgcccg gatctgatta tccgctccct gcgcggcaac gtcggcactc
    16501 gcctgagcaa actagataac ggcgaatacg atgccatcat tcttgccgta gccggactaa
    16561 aacgtttagg tctggagtcc cgcattcgcg ccgcgttacc acccgagatt tctcttccgg
    16621 cggtaggaca aggtgcagtc ggtattgaat gccgccttga tgatacgcgc actcgcgagc
    16681 tgcttgccgc gctgaatcac cacgaaactg cactgcgcgt taccgcagaa cgcgccatga
    16741 atacccgtct cgaaggtgga tgtcaggtgc caattggtag ctacgccgag cttattgatg
    16801 gtgaaatctg gctgcgtgcg ctggtcggcg cgccggacgg ttcgcagatt attcgcggtg
    16861 aacgccgcgg tgcgccgcaa aatgccgaac aaatggggat ttcgctggca gaagagctac
    16921 tgaataacgg cgcgcgcgag atcctcgctg aagtctataa cggagacgcc ccggcatgag
    16981 tatcctggtc acccgcccgt ctcccgctgg agaagagtta gtgagccgtc tgcgcacact
    17041 ggggcaggtg gcctggcatt ttccgctgat tgagttttct ccgggtcgac aattaccgca
    17101 acttgctgat caactggcgg cgctggggga gagcgatctg ttgtttgccc tctcgcaaca
    17161 cgcggttgct tttgcccaat cacagctgca tcagcaagat cgtaaatggc cccgactacc
    17221 tgattatttc gccattggac gcaccaccgc actggcgcta cataccgtaa gcggacagaa
    17281 gattctctac ccgcaggatc gggaaatcag cgaagtcttg ctacaattac ctgaattaca
    17341 aaatattgcg ggcaaacgtg cgctgatatt acgtggcaat ggcggtcgtg agctaattgg
    17401 ggataccctg acagcgcgcg gtgctgaggt cactttttgt gaatgttatc aacgatgcgc
    17461 aatccattac gatggtgcag aagaagcgat gcgctggcaa tcccgcgagg tgacgatggt
    17521 cgttgttacc agcggtgaaa tgttgcagca actctggtcg ctgatcccac aatggtatcg
    17581 tgagcactgg ttactacact gtcgactatt ggtcgtcagt gagcgtttgg cgaaactcgc
    17641 ccgggaactg ggctggcaag acattaaggt cgccgataac gctgacaacg atgcgctttt
    17701 acgggcatta caataactct cataacagga agccataatg acggaacaag aaaaaacctc
    17761 cgccgtggtt gaagagacca gggaggccgt ggacaccacg tcacaacctg tcgcaacaga
    17821 aaaaaagagt aagaacaata ctgcattgat tctcagcgcg gtggctatcg ctattgctct
    17881 ggcggcgggt gtcggtttgt atggctgggg taaacaacag gccgtcaatc agaccgccac
    17941 cagcgatgcc ctggctaacc aactgacggc attgcaaaaa gcccaggaga gccaaaaagc
    18001 cgagctggaa ggcattatta agcaacaagc tgcacagctt aagcaggcga atcgtcagca
    18061 agaaacgctg gcaaaacagt tggatgaagt ccaacaaaag gtcgccacca tttccggcag
    18121 cgatgctaaa acctggctgc tggctcaggc cgattttctg gtgaaactcg ccggacggaa
    18181 gctgtggagc gatcaggacg tcacgaccgc tgcagcgttg ctgaaaagtg cagatgccag
    18241 cctggcggat atgaatgacc cgagtctgat taccgttcgt cgggcaatta ccgatgatat
    18301 cgccagcctt tctgcagttt cgcaggtgga ttatgacggc atcatcctta agcttaatca
    18361 gctttcaaat caggtagata acctgcgtct ggccgataat gacagcgatg gttcgccgat
    18421 ggattccgac ggtgaagagc tttccagttc catcagcgaa tggcgtatca atctgcaaaa
    18481 aagctggcag aactttatgg acaacttcat tgcgattcgc cgtcgtgatg acaccgccgt
    18541 accgctgtta gcgccaaatc aggatatcta tctgcgcgaa aatattcgct ctcgcctgct
    18601 ggtcgcagca caagctgtac cgcgtcacca ggaagagact tatcgccagg cgctggagaa
    18661 cgtctccacc tgggtacgag cttactacga tactgatgat gccaccacca aagcgttcct
    18721 cgacgaggtg gaccagttaa gccagcaaaa tatctcgatg gatcttccgg aaaccctgca
    18781 aagccaggcg atgctggaaa aactgatgca gacccgcgtg cgtaacctgc tggcacaacc
    18841 ggcagcgggg acaacggaag ctaaacctgc acctgcacct gcacctgcac ctgcaccgca
    18901 aggtgatact ccggcagccg cgccgcaagg agaataacca tgctaaaagt gttattactc
    18961 tttgttttgc tgattgcggg gatagtggtt ggcccgatga ttgccggtca tcagggttac
    19021 gtgctgatcc agactgacaa ctacaatatc gaaaccagcg tcacgggcct ggcgattatt
    19081 ttgattctgg cgatggtagt gctgtttgcc attgagtggc tactgcggcg gatcttccgc
    19141 acaggcgcac acacccgtgg gtggtttgtc ggacgtaagc gtcgccgtgc ccgtaagcag
    19201 accgaacagg cgctgctgaa actggcggaa ggcgattatc agcaagttga aaagctgatg
    19261 gcgaaaaatg ccgatcacgc ggaacaaccg gtggtgaact atctactggc tgccgaagcc
    19321 gcgcaacaac gtggtgatga agcacgcgcc aaccaacatc tggaacgcgc agcagagctg
    19381 gccggcaatg acaccattcc ggtagaaatc acccgtgtac gtctgcaact ggcccgtaat
    19441 gaaaaccatg ctgcacgcca cggcgtggat aagctgctgg aagttacgcc acgccatccg
    19501 gaagtattac gtctggcgga acaggcgtat atccgcacag gtgcatggag ttctctgctg
    19561 gatatcatcc catcaatggc gaaagcccat gttggtgatg aagaacatcg tgcaatgctg
    19621 gaacaacagg catggattgg cctgatggat caggcgcgtg ccgataacgg tagtgaaggt
    19681 ttgcgtaact ggtggaaaaa ccaaagccgg aaaacgcgtc atcaggtagc gttgcaggtg
    19741 gcaatggcgg aacatcttat tgaatgtgac gatcatgata ctgcccagca aattatcatc
    19801 gatggcctga aacgccagta cgacgatcgc ctactgctgc cgattcctcg actgaaaacc
    19861 aacaatccgg aacagctgga aaaagtgctg cgccagcaga tcaaaaacgt cggcgatcgc
    19921 ccgctgttgt ggagcacact gggccagtca ctgatgaagc acggagaatg gcaggaagca
    19981 tcgctcgcct tccgcgcggc gctgaaacaa cgtccggacg cctacgatta cgcatggctt
    20041 gccgacgcgc tggacagact gcacaagccg gaagaagctg cagcgatgcg tcgcgacggt
    20101 ttgatgttaa cgttgcagaa caacccacca cagtagttcc ttctcacccg gaggcaagca
    20161 cctccgggac ctttctgatg cataaaaaaa cgcctgctct tattacggag caggcgttaa
    20221 aacaggtctg tatgacaaca agtgggtgct tcactcaacg ttgtgtccat ggtgtctgat
    20281 gaggcataag cgacatctgt cagtggacga taagcaccgt aaacggctct gcgtcattcc
    20341 ggagtttatg aggcactaag gcgaacataa gagatggaat gagcatctac ccgtttatta
    20401 tgccacagag aatcgggaaa taacatccct taacacttgt tatgagataa ttctgtaatc
    20461 ctctttgctt cctgagtaat aacttcctga gtgaatattt aacctgagct tgatcctaca
    20521 catacttatt atgaatgata aaattcattc aattaataac acatatatta attgccgtta
    20581 aaactaaaaa agcatcaata atcaacgtga tataataaac ctgccttaca tatcaactgc
    20641 gccagaggta ggattgaaaa cgctctcctg attttccaat tcattttctg gataaataaa
    20701 taatttattt ttatcactat tatttatgta atcatcctgt cagggagagg gatctcaatt
    20761 atcaatgctt aattacgtca tcattttgat gacatgaaac cggagcattt tgcatggaat
    20821 tttcgttttc acccaaactt cttgttgttg ctgtcgccgc cgctcttcct ctcatggcca
    20881 gcgcagcaga taccccgtca actgccaccg cacgcaaagg ctttgccgga tacgatcacc
    20941 caaaccagta tccacagaac gctgcaattt attgaatttg cacgatcatg taggccggat
    21001 aaggcgttta cgccgcatcc ggcaatcaac cgcaggcggc cacaaaatgg ccgctttttt
    21061 acttattcac caccagcaaa tgtgcctgca taatgtcact ggccgggcga ccgtgcgcca
    21121 gcaaatcagc cattgcttta agatatggcg gtagatggcg gaaataacgc tgatacccgg
    21181 cacacaaata attcagcccc ggtttgccgc tggcatcgag catgaagcgg tgtttcgggc
    21241 agcctcccca gcacgctttt aacacgttac aactgcgaca ctgcgccggt aattgcttaa
    21301 atttatcttc accaaacacc tgctgttgcg gggaatcgat catttctgca attgtttgct
    21361 gatgcatatt ccccagccga tattgcggat aaacatagtg atcgcaggcg taaacgtcgc
    21421 cgttgtgctc aacaatcacc gagcgcccac aggttggctg atgatggcaa accgcacccg
    21481 gcgcaccgac aaaattggca aacgcccatt cgatattcat cacgaaaatc ttgccgacgt
    21541 cgcgtttgat ccagtggtcg aatatcgcca ccagaaattc accaaattca tcggggcgca
    21601 ccgaccattc cgtcagttcc ccctgaatat caccaggcgc atgtagtttc agtccatcgc
    21661 tggcagctgt ttcatcagcc aggcgctcga ccaccggaat aaactggatg aattcgactc
    21721 ccgcatcgca caaaaaatca taaacctgca acggttgctg cgcgctggtg cggttgacgc
    21781 agaccagcac gttatagtcg acatgatgtt tttgcagcag cgtcagggca cgcatcacca
    21841 gcttatgcgt tggtctgcca cctttggtca cgcgatattg attgtggatc tcagccggac
    21901 cgtccagcga taacccaaca agaaaatgat tttctgccag aaatgcacac catttatcat
    21961 cgagcagcac gccgttagtc tggaagctgt tacttatctt cctgccagca ccgtatttcg
    22021 cctgtaactt tacggcacgg cggtaaaaat ccagcccgag taacgttggt tcgccgccct
    22081 gccaggtaaa agccacttcg ttttgcggtt cgctggcagc gatatagtga cggacatacg
    22141 cttccagcgt gtcatcgtcc atatgcgtga ctggcttttc gcggtaaagg gattgttttt
    22201 cgagataaaa acagtagtca cagttcagat tacaatcgga accactcggt ttcgccatca
    22261 catgaaaagc acgcgttgga acctgttgca gcatggtcac tccttgcctg aagtcatcct
    22321 tcaatacgtt aagggcgaaa tcataccgtg gggcaatgag ttattacggg cgtttattgc
    22381 gaagggaggg tgacgaaatg cacagaaaac aaaaaacccc gccgaagcgg ggttcaaaat
    22441 tggtcggcga gagaggattc gaacctccga cccactggtc ccaaaccagt tgcgctacca
    22501 agctgcgcta ctcgccgaaa tactgctttt tgaattttta gttcaattct ttaaagtcgt
    22561 ggtgcgaggg gggggacttg aacccccacg tccgtaagga cactaacacc tgaagctagc
    22621 gcgtctacca attccgccac cttcgcattg tcacaacttc taataatggg gtggctaatg
    22681 ggattcgaac ccacgacaac tggaatcaca atccagggct ctaccaactg agctatagcc
    22741 accactacaa atcttgttac gcggtattac taccaccgca gctcaagcgc cgggactaaa
    22801 tggcgcgccc gacaggattc gaacctgaga cctctgcctc cggagggcag cgctctatcc
    22861 agctgagcta cgggcgctta gcgccgttgc gggggtggat aatacggact tcccacccct
    22921 ctgtctagtc cctttttaaa taaattgcgc gtttggttac ggtttgtgcg ttttgctgat
    22981 tattcctcca gtttatgcgc tttcccgtgg cgattaaggc caaaaacttt ataaatcgcc
    23041 gtcaccgcca gcataaagat gatgccaaca aacagcgaca tacgcgtatc ttcattaaag
    23101 tacatgccga tcaaaacgca aatcaggaat gccattgtta cgtagttggc ccacgggaac
    23161 aggattgagc ggaacggatg gctggcaatc gccgctttat gtgcacgccg aaaacgcagc
    23221 tggcttatca atatcacaaa ccatggcacc atccccggaa gcacgctggc actgtagacg
    23281 tagacaaaca cacgctgcgg attgggaatg atgtagttca ggcatgagcc aattagcaga
    23341 atagcaatag atactgccac acccgcaacg ggtacgccgt gacgggaaac tttcgccatc
    23401 gccgccggta actgacggtt tttcgccagt gcgtagagca tacgtccgca actgtacatg
    23461 ccgctgttac agccagagag cgcagccgtc agcaccacaa agttgataat gcccgccgct
    23521 gcggtaatac cgattttggc aaaagtcagt acgaacgggc tgccgttgct gcctatttca
    23581 ttccacggga agatggtgac gataacgaaa atcgcgccta cgtagaaaat caggatccgc
    23641 cacagcacct tgcctacggc actgcgcagc gtcacctgcg gattcttcgc ttcaccggca
    23701 gtaatgccaa tcagctccac gccctggtag gacgccacca caatacacag cgcggtcagg
    23761 aaccctttcc agccacccgc aaagaaaccg ccatgctctg tgagattgct aaaaccaatc
    23821 gactgcccgc cattgccaaa gccaaagaaa atcacgccca gaccaatgac aatcatcacg
    23881 ataatcgtgg tgactttgat catcgcgaac cagaactcga tttcgccgta caaccgcacc
    23941 gccgccagat tcgccaacgc caccagcgcc actgcgatca atgcgggtat ccactgcgcc
    24001 atctccggga accagaactg gacataaacg ccaatggcgg tgatttctga gatccccacc
    24061 gccatccaca taaaccaata agaccaggcg gtgagataac caaagaacgg gctcatataa
    24121 cgatgcgcat aaacggcgaa cgaaccggta accggttcga ggaacaacat ttcgcccatt
    24181 gaacgcatga tgaaaaagac gaatagcccg gcgatgatat aggccaacaa tacggatggc
    24241 ccggcccatt tcaaggtact ggcggccccc ataaacaggc cgacgccaat ggtgcccccc
    24301 agggcgatga gttcgatatg tcgagcttcc agcccacgct gtagctctgg tttgttatct
    24361 gccataaatc ctcgtgttgt gtttgcatgc tttccggtgt taccggttat cgttatgggt
    24421 acatcgagtg ttgcgaatgt tttcgtaatt caggagaaat ggcaaataaa gcattaaaaa
    24481 tttgaatgct ttgtgtaata aaaaagcaga caggcgacgg agtgaccact ccgtcgcttt
    24541 acaaagagag gaaaatcaga ggttgccggt gtagtgccag cgtaaataac gcagcaaacg
    24601 aagctgacgc ttaatgcggc tcggctgcga aagcaggcgg tagagccact ccagtcccag
    24661 cgtttgccag attttcggtg cgcgttttac gtgaccggtg aaaacatcgt aagtcccgcc
    24721 aacgcccata tacagcgcat ctggatgcac cagacggcag tcgcgcatga agatctcctg
    24781 ctttggcgat cccatcgcaa cggtgacgat ttgcgctccg ctggcatgaa tgcgttcaaa
    24841 cagcgcctga cgctgctcgg gtttaaaata accatcctga ctgccaacga tattcacatt
    24901 ccattggttg cgcagtttag cttcagtttg cgccagcact tcaggtttac cgcccacaag
    24961 aaataccggc gtcccttctt tgcctgcgcg cgccatcagc tcttcccaga gatcggcacc
    25021 ggcaacgcgg gaaacctgcg cctgcgggta ctttttacgt actgaacgta caacgctgat
    25081 gccatccgca tatttaaatt cggcagcgtt aattaactcc ctgacctcgg cgttatcttc
    25141 aatggtcagc attttttcgg cattaatggc aaccagcgtt ccctgcttaa gctgcccgtc
    25201 agcaaacaga taatcgaggg cgtgctgcat atcacgccaa ccaatcaact gtaagccacg
    25261 cagcgtatag gtcggtgccg tggtgttgtt attcattgtt atccttcaac ctgcgtccgg
    25321 agcgatgatt ttgtacgttt atgaatgagt ccggcgcttt caaaaagcca gtacaacagt
    25381 tttgcgatca tcagacatgc gccgaagacc acgataaaaa agactacgcg tgagacaaac
    25441 gaatccagcc cttcacgtgc cagcacgatc atattgaaga tcgccccaaa gcagaaactg
    25501 tgcaatatcg cagccttata gcgattagtc tcgcggttgc ccagctcata cagccagtcg
    25561 aaccatttga tgatcagtcc aaccacaatc gccccgagtg ggatgaacaa cgcgccgccc
    25621 atcaccacca gtgagcctat aagcgtaggc gagatcgcca gtccggagtg gttattcagc
    25681 acttcccagg taaagtagtt ggctgagttc agcaccatac tcgggcgacc cggccacagc
    25741 caggaaggga taaagacata gaaatcgcgg acaattggag ccaggccctg gaagtcgatg
    25801 ttgtcgtagt tctgcaacag caacgccaga ttctcccatg gcgagaaggt gtcgcgagtg
    25861 agatagagaa acgtatagaa cgcttcatcg ccgctcacat tcattccata gcgttttagc
    25921 gccagccaga acatgcccac aatccccagc acgcccgccg ccgccagcat ccacaacgaa
    25981 atccagccgc gaataatgcc aataaacagg aagatagcga atgcgatgat gatattggcg
    26041 cgagtgccgc cgacaatcat ataagtcagc aagccaaagg cgaccgtgct gacgaggaaa
    26101 aacagccacg ctttgctatc ctggcgcaga aagtagacca ccagcatcgc cgggatgaaa
    26161 aagtaaaaga agcgttttaa cgccacgccg gagacttcac tggagaagat ctgactgtag
    26221 gagttaagcc ggaacagcaa aaagccgttg tgcatgaaga agatgccgac gcttaccagc
    26281 gcgatgccca tcaggatcac ccacgtaaga ttggtctcca cgcggttcat ggtaaacagc
    26341 ggacggcgcg gtacatcagc aacgcgtttg cgtaggcggg ttttgtaggt gacatagtaa
    26401 accgcgtaga agcagcccgc agaaagcaac gcctgcaaca agatttctgg cggcgcgaca
    26461 ccaacatcaa agcgaaatac cagcacgctg gtcagcggga agccgaagaa aaaggtgagc
    26521 aaaaacagca atgaaaagaa gacattgaag ttaaagcgca cacggcgaaa ctcaaaccag
    26581 gtcagcgtgg caataaacag cgtgcagagc agccagacaa caaacaggcc actgaattgc
    26641 agcagactca tgcgacctcc ccggcggcaa tcgccaacgc ccgctgccag ccttgtagat
    26701 agttagggct aaagaaggca atggtgtttt tatccaccga cgccaactgg cgctgcgctt
    26761 cacgcacaat atcctcgttg agatcgtcgg tagtaaacag caccggcaaa tgctgttccg
    26821 tcatatcctg ccagaacgga ttttcccggt taagcacaca aggaatgccc gcctgaatca
    26881 gtaagcaaag cgtaccaatg ccctgctggc gggcaaaaat aaagtaacca agatcgcact
    26941 gacgaagtag cgccagatag gcgtcaaatt ccagtttttc gctcaaaatt tgcagatttt
    27001 cttcgctgaa taactccagc cccgcctgac gaacttcctc aatgtacgct tcgttattag
    27061 gcggatatcc catcggcacc accactttta ccgtatcgcc aaattgctga tgaacggcgc
    27121 acaaggcagc aatatggtca ttgctgcggt caccggagtt ccccaccaga atggtcattt
    27181 tcccttcacg ttgccgatcg ttcgccatcg tattgagaga agggtccatc cgcgtcggga
    27241 agtacagcag ttcgccccgc acctttggat gcgttttggc aaaaaagctc aaatcgccgc
    27301 gggcggcaaa tacacagccg actcgctttt gcgccaggcg acgtagtggg taaaaaagct
    27361 tatatctcaa gccactggaa agctcataca ggtctgcccc ccagatatgc cagaaaaact
    27421 ggctgggctt aatgccacca ctcagcagag ccagccacag tgtgggattg aactgaccgt
    27481 ggaagaaaaa acgctgctga cggttagctt ttgctttcgc gatgaccgct tccgccagcg
    27541 attttttccc agggaaaaat tgcacagaaa gcgccggaca gctatcactt aagccgtcgt
    27601 ccttgccaac aaccataaac tcgcgcgcgt gctcgctcgt cgcagccagc gcgtcattga
    27661 aaaaccgcaa aacggttcgg ttatggtgag ggatatccga tcccagtacg tgaatcagta
    27721 cagtcatgcc cgcctacgcc agagtaaaaa cacgccacaa caaagagaaa aatagacgat
    27781 ataagttgcc atatatgcct gcgccgcgcc cagtgcacca tgcgcaggga ttagccagtg
    27841 ggcaaatacc atcaataaag tgaactggct gatttccgcc agaatataaa accgcaatga
    27901 cgctttggcg atcaccagat aaccaaagac ataagcgccc acttttaaca catcacccac
    27961 taactgccag gcaaagagat cgcgcatagc ggtaaattta ttcgacaaca gcagccagat
    28021 agcaaaatca cgcagcagcc agacggtaaa actcgccgcc gccactgccg gtaagacgaa
    28081 tttcagcgat ttaaccactt cccgggtgat atcgcgcttt tccgttagcc gcgacaacgt
    28141 gggcagcaaa tatacgctga acgatgccgt aataaattgc aggtaggcat cggaaatact
    28201 gctcacccct tgccagatcc ccacttcatc ccagctatac tgcgccgcca gcagtttacg
    28261 catcatgatg taagcaacag gcaaggtcac cgacgtaatc aacgccatga gcgtaaattt
    28321 gctcaactgc cctgccagac cgttatccca gctgggtttc agatagctta acgggatgac
    28381 accacgtttg atcaacatga tagcggcagg aattaccacc agcgcgggaa tcagcgccag
    28441 acccagcaac gccccttcat aaccgcccaa acggtaactg acgtagtacg cgagaacgcc
    28501 aatcaagctg ccgacaatca gcgataacgc attacctgcg gcatcgcgaa agcctttcat
    28561 cagcgccagt aacaggttgc cccaggcgat ccccatttgc accagcgcca ctaaacgcac
    28621 cagcccctga tagtcggtat taccaaacaa tccctggctg attggcgcag ctgccagcac
    28681 aaaaaccagc gccatcagcg tagagaaacc aagtaccatc gctgatgaag tgccgaccac
    28741 gcggcgcagc tgttgcggat tatcatggta ctgggcaacg tatttggtta caccgttaaa
    28801 gatgccagct ccggcaagca cgccgagcac ggtaatcaac tggcggaaat ttgccgccag
    28861 cccaagcccc gccggaccaa atgacacagc cagcaactta ccgaccagta acccggcacc
    28921 aatcttgacc agtgtactgg ccgccgtcca caaggacgct tttgccaacg acatatcagg
    28981 agaagtagtt caacaaagtc gcaattaccg tacgctgatt gacgggcgac aggttgtaga
    29041 acagcggcag gcgcagcagg cgctcgctct ctttggtggt gtagcgatct tcaccgtgga
    29101 actcaccaaa gcgttccccc gcagggcaac cgtgcagcgg aatgtaatgg aacaccgcca
    29161 tgatttccgc ttctttcaga aagttaatca acgcgctccg gtcatcaata tcccgcagtt
    29221 taatgtagaa catatgcgcg ttctgcacgc agccatcggg aatcgacggc agctcgatac
    29281 gcccggcttt cgccagaggc gctaacgcat cgtagtagtt ttgccacagc gccagacgtt
    29341 gctggttgat acgatccgct gcttccagtt gcgcccacag gtacgcagct tgcagatcgg
    29401 acatcaaata gctggagcca atatcgcgcc aggtatattt atcgacctga ccacggaaga
    29461 actggctgcg gttagtgccc ttttcacgga tgatctcggc tcgttcgatt aacgctttat
    29521 cgttaatcag cgtcgcgccg ccttcaccac ccgccgtata gtttttggtt tcatggaagc
    29581 taaagcagcc aatatgacca atggttccca gtgcacgccc tttgtaagtg gacatcacgc
    29641 cctgagcggc atcttctacc acaaacagat tatgcttttt cgccaacgcc ataatggtgt
    29701 ccatttcgca ggccacaccc gcgtaatgga ccggcacgat aacgcgcgtt ttgtcggtga
    29761 tcgccgcttc aatcagcgtt tcgtcgatgt tcatggtgtc cgggcgaaca tccacaaaaa
    29821 cgatttttgc gccacgcagc acaaaggcat tggcggtgga gacaaaggtg tagctcggca
    29881 tgatcacttc atcgccaggc tggatatcga gcagcagcgc cgccatctcc agcgaagcgg
    29941 tgcaggacgg cgtcagtaac actttggcgc tgccaaaacg ttgctccagc cactgctggc
    30001 agcgacgggt aaaaccgcca tcgccacaca gtttgccgct acccattgcc gactgcatat
    30061 agtcgagttc ggttcccacc accggcggtg cgttaaatgg aatcatgtga tcacctgtat
    30121 aaccagtacg cggtgctttc tacattcgca ccactttgta tgtatcgttt aagcgcggcg
    30181 gtgttgccca tttgggtcgc cacccgcaaa gttgttttac cgcgagcata cgcccagttt
    30241 agcgccgttt gcatcagctc agcacctaca ccgcgtccag ccagcaggcc aattcgcgca
    30301 tctgtcgcat tgagttcccg taaagagaca taaccacgaa taccgccgga cgccgcacgt
    30361 aaaatcagac attgatgatc aaaggtgccg cgcacggcat tttcaatcca ctgtgcataa
    30421 aagcgtctgc tggcgtcagg cgcataccac ggcgcacgaa aacggctttg cgcaaatgcg
    30481 gcgctggcta actgacgtaa tgcgggaata tcggtctctt gtgccactac agcaccacta
    30541 tcactgacat tgttcacggg tagtgccaaa tcaacttcac cttctaccag ggagaatccc
    30601 agctgttgca gggcatccag ttcacccgta tttgatgccg caattttggc ctgcacccgt
    30661 gaccacggcg ctaacacgtc tggcgtcagg agcggtgctt cagacgtaat gcgcacgatg
    30721 gcgctgttaa caccaaagaa ggcgttttcc caggttagtg gctcaatact ggcgcggacg
    30781 ggcacgaagt aactccagca gatattggcc gtagccagtt ttcgctaatg aactggcagc
    30841 acgcttcaca ccctcgtcat cgagccagcc gttacgccag gcgatctctt ccaggcaggc
    30901 aatcttaaag ccctggcgtt tttctactgt ctgcacaaag gtactggctt caatcaggct
    30961 gtcgtgagtg ccagtgtcca gccaggcaaa tccgcgcccg agcagttcaa cggtcaggtt
    31021 gcccgcctcg aggtacatct ggttgatgga ggtaatctcc agttcaccac gctccgacgg
    31081 cttcacctgc tttgcgtact ccacgacttt actgtcgtag aaataaagcc cagtcaccgc
    31141 ccagtttgac ttcggctgtt ttggcttttc ttccagcgag atagcgcgga aattgtcgtc
    31201 aaactccacc acgccaaagc gttccgggtc catcacctga tagccaaata ccgtcgcccc
    31261 ttccgtgcgc gccgcaacat gacgcagctt cggactgaag ccctgaccga agaagatgtt
    31321 atcgcccagc accagacaag aaggttcacc gttgaggaag gtttcaccga tgataaaggc
    31381 ctgcgccaga ccgtccgggc tgggctgttc ggcgtattcc agctggatac cgaactcact
    31441 accatcgccc agcaggcgct ggaaataacc tttatcttcc ggcgtagtga tgatgagaat
    31501 ttcgcggata ccggccaaca tcagcaccga cagcggatag taaatcattg gcttatcgta
    31561 aatcggcaac agttgcttcg atacgccgcg cgtaatcgga tgcaatcggg tgccggaacc
    31621 gcccgccagg ataatacctt tcatgtttgc ctccgctgaa aattagcctt tcagacctaa
    31681 acgctcgccc tgatagctgc cgtcctgcac ctgcttccac cagctttcat tagccagata
    31741 ccactgcacc gttttacgca ttccactttc aaaggtttcc tgtggcagcc aaccaagttc
    31801 acgggcaatt ttcgaagcat caatggcata acgcagatca tgccccggac ggtcagcgac
    31861 aaaggtgatc aagtcacgat agtgcaccac gccgtgcggc ttgttcggag ccagttcttc
    31921 cagcagctcg caaatggttt ccacaacatc gagattctta cgctcgttgt gaccaccaat
    31981 attataggtt tcaccgactt tcccggtggt cgccacgcaa tacagcgcgc gggcgtgatc
    32041 ttccacatac agccagtcac ggatttgctg cccgttgcca tataccggca gcggtttacc
    32101 cgccagcgcg ttgaggatca tcagcgggat cagtttttcc ggaaagtggt aaggaccgta
    32161 gttattcgag cagttggtga tcagcgtcgg cagaccgtag gtccgcagcc aggcgcgcac
    32221 cagatggtcg ctgctggctt ttgacgcgga ataagggctg ctcggcgcat acggcgtggt
    32281 ttcggtgaag aaatcatccg tcgagtgcag gtcaccatat acttcgtcgg tggagatatg
    32341 atgaaaacgg aacgctgatt ttttatcttc cgtcagcgta ttccagtaag cccgcgccgc
    32401 ttcaagcaat gtataagtcc cgacaatgtt ggtttcaata aacgctgccg ggccgtcaat
    32461 agaacggtca acatggcttt cggctgccag atgcatgaca cagtctggct gatgctcagt
    32521 gaatacgcgt gccagttctg cccgatcgca gatatcaact ttctcaaagg caaagtgctc
    32581 gctttgcgcg accggtgcca gcgacatcag gtttccggcg taggtcagct tatcgaccac
    32641 taccaccgca tcgctcgttt cgttgatgat ataacgcacc agcgccgagc caataaaccc
    32701 ggcaccacct gttatcagaa tttttctcat cagcgccaga ctcctttggc atcgacgaca
    32761 tactgctgat ggacattgtc gccattgata actttgaact gactatgatc gaccagcatc
    32821 accagcacgt ctgccgttgc cagcgcctcg tcaagctgcg ccagagtaca aagcccggtc
    32881 agttttttcg gcaactggtg gatgttaggc tcaacaacca gcgtttcgcc gctgtgccac
    32941 tgggcgatca gttcagcgat ttccatcgcc gggctttcgc gcaggtcatc aatattcggt
    33001 ttaaacgcca gaccaaagca ggcgattttc agttcactgg cgcgtttatc ggtagcagca
    33061 aggcagtcgg caaccgccgc tttcacctga tcgataaccc agaacggttt gtgatcgtta
    33121 acttcgcgcg cggtacggat aagccgcgcc tgctgggggt tctgtgccac gataaaccac
    33181 ggatcaacag caatgcagtg accgcccacg ccagggccag gctgaagaat attaacgcga
    33241 gggtgacgat tcgccaggcg aatcagttcc cagacgttaa tcccctgatc ggcacaaatc
    33301 agcgacaatt cattagcaaa agcgatattc acatcgcgga agctgttttc ggtgagctta
    33361 cacatttccg ccgtccgcga gttagtgacg acacactcac cttcgaggaa aattttgtac
    33421 agttcgctgg cgcgggtcga acaaaccggc gtcataccac caatcacgcg atcgttttta
    33481 atcagctcga ccataacctg gcccggtaac acgcgttccg ggcagtaagc aatgttgacg
    33541 tccgcctgct cgcccacctg ctgtgggaaa gtgagatccg gacgcatctc tgctaaccat
    33601 tctgccatct tctcggttga ccccaccggc gaggtggatt caaggatcac cagcgcgcct
    33661 tttttcagca ctggcgcaat ggagcgagca gccgattcaa cgtaggtcat atctggctca
    33721 tgatcgcctt taaacggcgt gggtacagca atcagccagg catccgcttc aactggcgtc
    33781 gtgctcgctc gtaaaaaacc gccttctacg gcagttttta ctacgctcgc caaatcaggc
    33841 tcgacgatat ggatttcgcc acgattgatg gtatcaaccg cgtgttggtt gatatcgaca
    33901 ccaatcacct gtttttgccg tgaggcaaac gctgctgctg taggcagccc gatgtaaccc
    33961 agtccgataa cagaaatggt cgcaaaactc atagtgatat ccgattattt tttaacgctt
    34021 ccagaatgcg agagcatgcc tgaccatcac catacgggtt atgggcgcgg ctcatagttt
    34081 gatattcgtt ttcgtctttt aaaagacgcg tcacttcctc gacaattcgc tgcttatccg
    34141 tgcctaccag acgcaccgta cccgccgtca ccgcttccgg acgctcagtg gtatcgcgca
    34201 tcaccagcac cggtttcccc agcgaaggcg cttcttcctg aatgccgcct gagtcggtca
    34261 aaatcagcca ggcgtggttc atcagccaga caaacggtaa atactcctgg ggatcgatca
    34321 gaatgacatt tttcacatgc cccagaatgc gattgaccgg ctctctgacg ttcgggttga
    34381 gatgcaccgg atagacaatc tggatgtcct ggtgcgtggt ggcgatgtct gccagcgcgt
    34441 ggcagatttc ttcaaagcca cgaccgaaac tttcacgcct gtgaccggtc accagaatca
    34501 tctttttatc ggggtcgata aacgggtaat ttgccgccag ttctgaacgc agcgtgtcgc
    34561 tgctcatcac ctgatcacgc acccataaca gtgcatcaat gactgtatta ccagtaatga
    34621 agattcggct atccgcaacg ttttcacgca gcaagttttg ccgggaagtt tcggttggag
    34681 agaagtgata catcgccaga tgcccggtca atgtacggtt agcctcttcc ggccacggcg
    34741 aatagagatc gcccgtgcgt aaaccagcct caacgtgacc aacaggaata cgctgataaa
    34801 acgccgccag gctggttgcc agcgtcgttg ttgtgtcgcc gtgaaccagc acgacgtctg
    34861 gtttgaactc ggcaagaata ggttttagcc cttccagaat ccgacaggtt atctctgtca
    34921 ggccctgtcc tggctgcatt atgttgagat cgtagtcagg tacaatggaa aagagtttca
    34981 gcacctgatc gagcatctcc cgatgctgcg cagtgacgca aactttagcc tcaaaaaaag
    35041 gatcttttgc caacgcatgc accaacggag ccatcttgat ggcttccggg cgcgtaccaa
    35101 atacagtcag tactttcaca tcgattctct tcgaataagc ggcgagcgcc tttgcgctcg
    35161 cagcagcagt gttgctattt cgagcaacgg cgggttaatg cgacaccagc cccgatcagc
    35221 cccccgacaa tgccccacat aatcatcagg aaggcacgac gtgggctatc gcgttttacc
    35281 ggttcttccg gcgtacgcaa atagcgatag gtctgaaaac gcggatccag ggttggacca
    35341 acattcaggg tgtttaacat ggcccgattc tgatcatagt cgagatcaaa ggccggaccg
    35401 acggcctgta aattttccag tcgagcctgg agcattggac gcccaagcag gaacatttct
    35461 gaatcaggta attcctcggc aggcacatct gtcgcactgc gcgaaatatt atgctgctca
    35521 gcaattttca gcgcctgctc aatgctgttc atccggcggt cgtagatggc tttcgccacc
    35581 tcttcctgac gcttcacctg agctttcatc tggatggtgc gtgccgccca tgcgcctttc
    35641 agctcatcat tcagatggct ggctgcacgc tggctggcaa aagcaacata ctgacgtaac
    35701 aggttattag cgtcaggcgc ggtttcggca ataagcttca cgctgtcatt gaccgcgcgg
    35761 gtaaagtctc cggggataaa ctggatgttg ttaatcattt catccagcaa cgccgcatcg
    35821 gctttgctgt tgcccaccat ccgctgcttg taatagtcgg tttgcagcca gaactctctg
    35881 cgggtatccc acgaggccag ttgcataaca aactctttat aggcttcgtc catgaccgat
    35941 ggttggtcgg cagaagccat gtttgaacgg gcatccaggt tacgcaaaaa ttgctgctgc
    36001 gagtaatatc cccccagcat attcaccgtt ggacgatcgg taatcgccgt cgcgctccac
    36061 tcttgtcgag caaaaaaagt atacgccagc gcgattaacg caaacgccag ccccatgcca
    36121 ataatccata gcttcccagc ccacaaggta cgaaacaacc cacgaatatc cagttcattt
    36181 tcagcgtctt cggccggttt cccaggcatt ggttgtgtca tcacatcctc atttatttgg
    36241 ttaaattggg gctgccacca cgatttctac gcagtctgcg ttttacgcgc ttaataaagc
    36301 gagcaacttt ccaggcacgc ttaatgcaat atccatagag gaagaatgct agcaaaaaga
    36361 gcaccagcat gacccactcc gggacaaaat gagaatattc tgccagcacg ccaatggaag
    36421 cgagcagtgc tgcggcaagg gtaatcagca caaacgcctg acgggaagta aacccggcac
    36481 gcatgatcaa atggtgaata tgctgacggt caggagagaa tgggctcatg cctttacgca
    36541 ggcgacggta cataatcgcc accatatcca ttagcggaat ggcgattatc cacaaagcgg
    36601 taaccgggct gatgggatgg gttttgccct gggtcgtttc gagcaggatc cagataacgg
    36661 taaaaccaat cagcgtactg cccgcatcac ccataaagac tttgtagcgg cgacccagga
    36721 taccaaggtt aagcatgatg tatggcagga tggcggcgat catcgcaaag caccagattg
    36781 cgaggctggt ttgcccgtcg aaccacaaaa tcataccgat tgctgcaaac gagacgcagg
    36841 acaacccgcc cagcaagcca tcaatgccat caaccatgtt gaacgcatta atggccgccc
    36901 agacggcaaa tagcgtcagg aagtaaccaa acggtccgag caccatctcc caggagccaa
    36961 agatataacc caggctactg agataaagtt tgccgaacac catcataaca atgccaacag
    37021 cggcctgtat ggtggcacgg atttttacgc tgatatcaaa acggtcatcc agcgcgccaa
    37081 tgaaaacaag cacaccggca caagcgagat agagagatgc atgcggaata tagtaatcga
    37141 caattccgaa cgtgaagcaa atccctgcgt aaaccgaaat ccccccaacg agaggtatca
    37201 atccctggtg acgtttgcgg aagtttggtt tatccactaa accgactttt tttgccactt
    37261 tacgggcaaa aaacagaaac agtgtcgtga ataaaaaaat actgatgaga tcagtactca
    37321 ctgtcagtaa attcacaatg catgctctca gagaaaatta ttagcagaag tataaccacg
    37381 aagaccttta ttcagaaggg aaagtccgtt ccgaacccac cagtcctgtg caaaaattaa
    37441 ccatttgata tgcaaattgc ataacatgcc agcaaattcc aggaattttc ctaacatcgc
    37501 cagcgcggca ttaagattac agatataaaa gcaaaacgcc acgtaaacac gtggcgtttt
    37561 tggcataaga caaatttatg agcgtttcat catttcgaag aaatcgtcat tggtcttagt
    37621 catggccagt ttattaatga ggaattccat tgcatcgatt tcgcccatcg ggtgaatgat
    37681 tttgcgcagg atccacattt tctgcagttc ttcctgagtc gtgagcagct cttctttacg
    37741 ggtaccggaa cggttgtagt cgatagccgg gaagacgcgt ttttcagcga tcttacgaga
    37801 gaggtgcagt tccatgttgc ctgtaccttt aaactcttcg taaataactt cgtccatttt
    37861 agaaccggta tcgataagcg ccgtcgcgat aatggtcagg ctgccgccct cttccacgtt
    37921 acgcgccgca ccgaagaagc gtttcggacg atgaagggca ttggcgtcca caccaccggt
    37981 caacacttta cctgacgccg gaacaacagt gttgtaagcg cgcgccagac gagtgatgga
    38041 gtcgagcaga atgataacgt ctttcttgtg ctcaaccagg cgtttggcct tctcgatcac
    38101 catttccgca acctgaacgt ggcgagatgc gggttcgtca aaggtagaag caacaacttc
    38161 accttttacc agacgctgca tctcggttac ttcttccgga cgttcgtcga tcagcagaac
    38221 catcagcaca caatccgggt ggttgtaagc aatgctctga gcaatgttct gcagcagcat
    38281 agttttaccg gctttcggcg gtgccacaat cagaccacgc tgaccacgac cgataggtga
    38341 tgccagatcc agtacgcgag cggttaaatc ttcagtagaa ccgttaccac gttccatacg
    38401 cagacgagag tttgcgtgca gcggggttaa gttctcaaag aggattttgt tgcgggcgtt
    38461 ttcaggtttg tcgaagttaa cttcgttaac tttcagcagc gcaaaatagc gttcaccttc
    38521 tttcggcggg cgaatcttac cagagatggt atcaccagtg cggaggttga aacggcggat
    38581 ttggctaggg gaaacgtaga tgtcatcagg accggcgagg taggagctgt ctgcggaacg
    38641 gaggaaacca aatccatcct gcaatatctc cagtacgcca tcaccaaaga tatcttcgcc
    38701 actctttgcg tgctgcttca ggatggcaaa aataatgtcc tgcttacgca tacgagccag
    38761 gttttccagc cccatatttt cgccgagagt gatcagctca gaaaccggcg tattctttaa
    38821 ttcggtaaga ttcatagtgg tgtgagttct taaacttggg gtaaatctcg aacttaatgt
    38881 tgtgaatggt atggcaggat catccatgcc tgtttacggt catcgactca tgtcttttcg
    38941 ctgcctggtc acaggagagt acgcagaact gaaacgacaa gacggattga gtgacgagcc
    39001 agaaatctgt tcacttcgca tttaagataa aacgggaagc gttggaaatt acaagattca
    39061 aacttaataa ggtatgttta atacgaagtc aacactaagt tagcatgact cacgccgggc
    39121 gtccagtttt tagcgacggg gcacccgaac atgaaattcc cttacgccag gttagcgtcg
    39181 aggaactctt tcaactgacc tttagacagt gcacccactt tggttgccgc cacttcaccg
    39241 tttttgaaca gcagcagagt cgggatacca cggatgccat atttcggcgc agtgccaggg
    39301 ttttgatcga tgttcagttt tgcaacggtc agtttgccct gatattcgtc agcgatttca
    39361 tccagaatcg gggcgatcat tttgcacgga ccgcaccact ctgcccagaa atcgacgagg
    39421 atcgccccgt ccgctttgag tacatccgtg tcaaaactgt cgtcagtcag gtgaataatt
    39481 ttatcgctca tatataactc cacaggaata agcctggcgt gttggtttcg ttgttggtgt
    39541 aacattaacc aactaaaggt tgactttatt tcaccggata cgctttcgta aagcaatagt
    39601 aagctgatat tctaccacac tatgagcaaa acacatttaa cagaacagaa gttttccgac
    39661 ttcgccctgc atccgaaggt tgtagaagcc cttgaaaaaa aagggtttca taactgtacg
    39721 cccattcagg cactggccct tccgctgacg ctggcgggtc gtgacgtagc cgggcaggcg
    39781 caaaccggta ccgggaaaac gatggcgttt cttacgtcaa cgtttcatta tcttctctct
    39841 catcctgcga ttgccgatcg caaggtgaat caaccacgtg ccttaattat ggcaccgacg
    39901 cgtgaacttg ccgtgcagat ccatgccgac gcagaaccgc tggcggaagc taccggcctg
    39961 aagctgggtc tggcttacgg tggtgatggc tacgacaaac agctgaaagt gctggaaagc
    40021 ggcgttgaca ttctgattgg cactacgggg cgtttaattg actacgccaa gcagaaccac
    40081 attaacctcg gtgccattca ggtggtggta ctggacgaag ccgatcgcat gtacgatctg
    40141 ggctttatta aagatatccg ctggctgttc cgccgtatgc cgcctgcaaa ccagcgcctc
    40201 aacatgctgt tctccgccac gctttcgtac cgggtacgtg aactggcgtt cgagcagatg
    40261 aacaatgccg aatatattga agtggaaccg gaacagaaaa cgggccaccg tattaaagaa
    40321 gagcttttct acccttctaa cgaagaaaaa atgcgtttgc tgcaaacgct gatcgaagaa
    40381 gagtggccag acagagcgat tattttcgcc aataccaaac accgttgtga agagatctgg
    40441 ggccacctgg cggcagatgg tcatcgtgtc ggtttgttga caggcgatgt cgcgcagaaa
    40501 aaacgtctgc gtattcttga tgaatttacc cgtggcgatc tggatattct ggttgccacc
    40561 gacgttgccg cgcgtggttt gcatattccg gcagtgacgc acgtctttaa ctacgattta
    40621 cccgatgact gtgaagatta cgttcaccgt attggtcgta caggtcgcgc aggcgcaagc
    40681 ggtcactcta tcagcctggc gtgtgaagag tatgcattga atttgcctgc tattgagacc
    40741 tatattggtc actcaattcc ggtaagcaaa tacaatccgg acgcattgat gaccgatctg
    40801 ccaaaaccgc tgcgcctcac gcgcccacgt acaggcaatg gtccgcgtcg tactggcgct
    40861 ccgcgtaatc gtcgtcgttc aggttaaata aaatgtcata ctcaaaatca ttcaaactgt
    40921 atcaagatgg caagagaatg aatcccgatg agcatactgt agtaagtgat tcaggtgaaa
    40981 gaatgcagcc aacacagaga cagattgaag gatgaagagt atgggttcca cctcgtcgct
    41041 gtatgcagcc attgatctcg gttcgaatag ttttcatatg ctggttgtgc gcgaggtggc
    41101 tggaagcatc cagacgctga cgcgaataaa acgcaaagtg cgtctggctg ctggcctgaa
    41161 tagcgaaaat gccctgtcta atgaagcaat ggagcgcggt tggcaatgtc tgcgcctgtt
    41221 tgctgaacgt ctgcaagata tccctccctc gcaaattcgc gttgtcgcta cggcgacatt
    41281 acgtcttgcc gtcaatgcgg gtgattttat tgccaaagcg caggaaatcc tcggttgtcc
    41341 ggtacaggtg atcagcggtg aagaggaagc acgtctgatt tatcagggcg ttgctcacac
    41401 aactggcggt gccgatcagc gcctggtggt ggatataggc ggtgccagta ctgaactggt
    41461 aaccggcacg ggtgcacaaa ccacctcgtt gttcagcctg tcgatgggct gcgtcacctg
    41521 gctggaacgc tattttgccg atcgtaatct ggggcaggaa aattttgatg ctgcagaaaa
    41581 agcggcacgc gaagtgttac gtccggttgc cgatgaatta cggtatcacg gctggaaagt
    41641 gtgcgttggt gcttccggca ccgtgcaggc gttacaggaa atcatgatgg cacaggggat
    41701 ggatgaacgc attaccctgg aaaagttgca gcaattgaaa cagcgagcca ttcattgcgg
    41761 tcggctggag gaactggaga ttgacgggct gacgctggaa cgtgcgttag tgttcccgag
    41821 tggtctggcg atcctgatcg ccatttttac cgaactgaat attcagtgta tgaccctggc
    41881 gggcggtgcg ctgcgtgaag gcctggtcta cggcatgttg catctggccg tcgagcagga
    41941 tattcgcagc cgtacgctgc gtaatattca gcgccgcttt atgatcgata ttgatcaggc
    42001 gcagcgcgta gccaaagttg cggctaactt cttcgatcag gtggaaaagg aatggcatct
    42061 tgaagcaata agccgcgatt tgctcatcag cgcctgtcag cttcatgaaa tcggcctgag
    42121 cgttgacttt aaacaagcgc cgcaacacgc tgcttatctg gtgcgtaatc tggatcttcc
    42181 cggttttacc cccgcacaga aaaaattgct ggcgacgcta ctgctcaacc agactaatcc
    42241 ggtcgatctc tcatcgctgc atcagcaaaa tgccgtaccg ccgcgcgtcg cagaacaact
    42301 ctgccgttta ctccgcctgg ccatcatttt tgccagccgt cgccgtgacg atctcgtgcc
    42361 agagatgaca ttacaggcta accatgaact gttgaccttg acgcttccgc aaggttggct
    42421 aacccaacat ccgctgggta aagagattat tgctcaggaa agccagtggc agagctatgt
    42481 ccactggccg ctggaagtgc attaatgagt aagtgccgga tgcgatgctg acgcatcttt
    42541 tccggccttg attatttccc tcgttttgcc gccatcatcg ctttcagatt cgccagatgg
    42601 ctttgccctt tctgcatccg ttcttcggcg ctgaccactt tgcgctcctg ttcccaaatc
    42661 agatcatcct gcggcagctc cagcaaaaag cggctcggct ccgggcgcac cagctcgccg
    42721 tactgacggc gttctttaca cagcgtaaag gtcaattcct tctgggcgcg ggtaatgccg
    42781 acataggcca gccgccgctc ctcatcgata ttatcttcat cgatgctgct ctggtgcggc
    42841 aaaaaccctt cttccatacc gaccatgtag acataaggaa actccagccc ttttgacgcg
    42901 tgcagagtca tcagttgcac ctgatccagc tcttcttcac tctcaccacg ctccatcatg
    42961 tcgcgcaaag taaagcgcgt caccacctgg gtgagcgtca tcggctcatc cagttcgctg
    43021 ccttccagca tctccgtcat ccagctaaac agttggttga cgttcttcat gcgcatttcg
    43081 gcggctttcg ggctgggcga tgtttcgtac agccaggatt cataatccat gccgtggatc
    43141 agatcgcgca ccgcggcaat cggctcccgc tccgccagac gctggatttc tgccaaccag
    43201 tgagtaaagc gggtcaatgc ttcataacca cgtccgctaa gcgtctgact caggcccata
    43261 tcaaagctgg cggtaaacat gcttttattg cgcgtcatcg cccactcacc cagctttttc
    43321 agcgtcgccg ggccaatctc tctcttcggc gtgttaacga tacgcagaaa tgcgctgtca
    43381 tcgtccgggt tagtcagcac gcgcagataa gccagcaagt ccttgatttc aggacgagag
    43441 aaaaacgacg taccaccaga aattttgtac gggatgcggt tttgcatcag gaatttttca
    43501 aacactcgcg actgatggtt accgcgataa agaatagcgt aatctttgta ctgcgtttta
    43561 ttgacgaagt gatgcgcaat cagttcacca gtgacgcgct cggcttcatg ttcttcgtta
    43621 ttcgcgctta aaactttaag ctctgtgccg taacccagtt cggagaacag acgcttctca
    43681 aagacgtgcg ggttattggc gatcaggatg ttcgccgctt tcaaaatacg tccggaagag
    43741 cggtagttct gctcaagctt aatcaccgtc agcgccggaa aatcctgact cagcagcacc
    43801 aggttttgtg gacgtgcgcc gcgccaggag tagatcgact ggtcgtcatc gcccaccacg
    43861 gtaaagcgcg cgcggctgcc caccagcagt ttcaccagct catactggct ggtgtttgtg
    43921 tcctgatact catccaccag cagatagcga attttgttct gccagcgctc gcggacttct
    43981 tcattgcgtt gcagcagcaa cgtcggcaat aaaatcagat catcgaagtc gagaacattg
    44041 cacgctttca ggtgtgcatc atacagccca taacaatggg caaaaatacg atcccgctcg
    44101 ccctttgcct ctgccgccgc ctgcgccgga gttttgagat cgttcttcca gttggagatg
    44161 gtcgaaatca gctgttgcag gagaactttg tcatcttcaa tcagcccctc ggtcaactct
    44221 ttaagcaaag caagctgatc ggtatcgtca aacagcgaaa agttcgcctt catcccaagc
    44281 gccgcatact cgcgtttgat gatatccaac cccagcgtgt gaaaagtgga gatcatcagc
    44341 ccgcgcgcct ctttgcgacc cagcgtctgc ccgacacgct ctttcatctc gcgcgccgcc
    44401 ttattggtaa aggtcaccgc cgcgatatgt cgcgcctgat aaccgcaacc gcggatcaga
    44461 tgggcgattt tattggtgat cacacgagtt ttaccggaac ccgcgcccgc cagcaccagg
    44521 caggggccgg taacgaattc gacagcttgt tgttggccgg ggtttagacg cataggtgta
    44581 ttgctcaatc ttcgaacggg gggaggattg tagcagaatc gcatttgaat gtgaccgcgt
    44641 gtaagccgct aaccggttgg ctgcggatgt ttaaatcaga gagagaagac cgaaatcgga
    44701 gttcatcgtg aatccattag acttagaaaa tatcgggtcg taacgttgtg ttattacttt
    44761 ttcagagttt actaaggaga ggtttactcg tggcgattaa tttcagccct aaggttggtg
    44821 aaatacagga atgcaacttt ggtaactatc ctgttatcca gaatggacag ttcagcacca
    44881 cgtattacga tggccgcatt cctcctgaaa tgataaaaaa caggttagtt gtcgtgctca
    44941 acggaaaaat taatggcaac gcatgtatcg tcgttccatt atcaaccact cgcgatcatg
    45001 acaagttaaa tcgtggaatg catgttgaaa tagccagtaa tgttatcaat gtcctgcaat
    45061 tctttgatca gcagattcgt tgggccaaag ccgacctggt acaacaagtc agtcgaaacc
    45121 gattaaatag agcaaggact tacagagggt atcttaatca atgtttgcca catgagttgg
    45181 ttgcagacat acagagggcg gtcatcaagt caatcaatgc catatcgctc ataaattgac
    45241 aataaaataa ccatccccga taatgacttt gtagcccata gaggccctaa gttttctccc
    45301 cttgagggac ctgcgaagcc cggattttcc gggcttttgc catatatgta ccagcccctc
    45361 cctgactgac aattacgtta gcatctgcgg atcatgctaa aatcgccgcc tgacaattat
    45421 tcactcaagg cacgatcatg gcaaaaacag cagcagcact gcatatcctt gtaaaagaag
    45481 agaaactggc tctggatctt ctcgagcaga ttaagaacgg tgccgatttc ggcaagctgg
    45541 cgaagaaaca ctccatttgc ccatcaggca aacgcggcgg tgatttaggt gaattccgcc
    45601 agggtcagat ggttccggcg ttcgataaag ttgtgttctc ttgtccggta ctggagccga
    45661 ccggcccgct gcacacccag ttcggttacc acatcattaa ggtgctgtac cgcaactaat
    45721 agcaaggcct tctccaggag aaggccttga gtgttttctc cctctccctg tgggagaggg
    45781 tcggggtgag ggcatcagcg cgcacttaac ccgcaacagc aatacgtttc atatctgtca
    45841 tatagccgcg cagtttctta cctacctgct caatcgcatg gctgcgaatc gcttcgttca
    45901 catcacgcag ttgcgcgtta tctaccgcgc cttccggaat agctttaccc aagtcgcccg
    45961 gttgcagctc tgccataaac ggtttcagca acggcacaca agcgtaagag aacagatagt
    46021 taccgtactc agcggtatca gagataacca cgttcatttc gtacagacgc ttacgggcga
    46081 tggtgttggc aatcagcggc agctcgtgca gtgattcata atatgcagac tcttcaatga
    46141 tgccggaatc gaccatggtt tcgaacgcca gttcaacgcc cgctttcacc atcgcgatca
    46201 tcagtacgcc tttatcgaag tactcctgct cgccgatttt gccttcatac tgcggcgcgg
    46261 tttcgaaggc ggttttgccg gtctcttcac gccaggtcag cagtttctta tcatcgttgg
    46321 cccagtccgc catcataccg gaggagaact cgccggagat gatgtcgtcc atatgtttct
    46381 ggaacagggg tgccatgatc tctttcagct gttcagacag cgcgtaagca cgcagtttcg
    46441 ccgggttaga gagacggtcc atcatcaggg tgatgccgcc ctgcttcagc gcttcggtga
    46501 tggtttccca accgaactga attagttttt ctgcgtatgc cggatcggtg ccctcttcca
    46561 ccagcttgtc gaagcacagc agcgagccag cctgcaacat accgcacagg atggtttgct
    46621 cacccatcag gtcagatttc acttccgcaa cgaaggacga ttccagcacg cccgcacggt
    46681 gaccaccggt tgctgccgcc catgctttag cgatcgccat accttcgcct ttcggatcgt
    46741 tttccgggtg aacggcaatc agcgtcggta cgccgaatcc acgtttgtac tcttcacgca
    46801 cttcggtgcc agggcatttc ggcgcaacca tgactacggt gatatcttta cggatctgct
    46861 cgcccacttc gacgatgttg aaaccgtgcg agtaacccag cgccgcgccg tctttcatca
    46921 gtggctgtac ggtgcgcact acatcagagt gctgcttgtc cggcgtcagg ttaaccacca
    46981 gatccgcctg cgggatcagt tcttcgtaag taccaacttt aaaaccgttt tcggtcgctt
    47041 tacgccagga cgcgcgcttc tcggcaatcg cttctttacg cagagcgtag gagatatcga
    47101 gaccagaatc acgcatgttc aggccctggt tcagcccctg tgcgccacag ccgacgataa
    47161 ccactttttt accctgaagg tagctcgcgc cgtcggcgaa ttcgtcgcgc cccataaagc
    47221 gacatttgcc cagctgtgcc agctgctggc gcaggttcag tgtattgaag tagttagcca
    47281 tggtgattcc tcgtgatgtt gtgcttctta ttgttcggtt cgcgtttgcg agattgaatt
    47341 cactatatga caggaaattt attgcggaaa ttgatatatt cacaacgtca cattgcaatt
    47401 tctgcaacat caacattgag ggctgcgcca ttggatttac gcgatctgaa aaccttcctg
    47461 catctggcgg aaagccgcca ttttggccgc agcgcgcggg cgatgcacgt tagcccatcc
    47521 acgctctcac ggcagattca gcgcctggaa gaagatcttg gtcagccgct atttgtgcgc
    47581 gataaccgca cggtaacgct gaccgaagcg ggcgaagagt tacgcgtttt cgcccagcaa
    47641 acattgttgc agtatcagca actgcgccac accatcgatc agcaagggcc gtcgctctct
    47701 ggcgagttac atattttctg ctcggtgacc gccgcttaca gccatctacc gccgattctc
    47761 gaccgcttcc gcgcggaaca cccgtcggtg gagatcaaac tcaccactgg tgatgcggca
    47821 gatgcaatgg aaaaagtggt cacgggaaaa gcggatctgg cgattgccgg gaaaccggag
    47881 acgctacccg gcgctgtggc gttttcgatg ctggagaatc tggcagtagt gctgattgcc
    47941 cccgcgctgc cctgcccggt gcgtaatcag gtatctgtcg aaaagcccga ctggtcaacg
    48001 gtgccgttta ttatggccga tcaggggccg gtacgccgcc gcattgaact gtggtttcga
    48061 cgcaataaaa tcagcaaccc gatgatttac gccacggttg gcgggcatga agcgatggta
    48121 tcgatggtgg cgctcggctg tggtgtggcg ctgttgccgg aagtggtgct ggaaaacagc
    48181 ccggagcctg tacgcaaccg ggtaatgatt ttagatcgca gcgatgagaa aacgccgttt
    48241 gaactgggcg tgtgtgcaca aaaaaagcgg ctgcatgagc cgctgattga ggcgttctgg
    48301 aggattttgc cgaaccacaa atgacgttgt cgcgcgggta ggcctgataa gcgaagcgct
    48361 atcaggcatt tttccctaac ccgccaaaaa gaacctgaac gccggattat tggtttcgtc
    48421 gtggcaatcg tagcccagct catttagccg ggtttcgaaa tccggttcat ggtcgccgag
    48481 ttcgaacgcc gccagtacgc gcccgtagtc ggtgccatgg ctgcgatagt ggaacaaaga
    48541 aatgttccag tgcgtaccca gcgtgttgag gaagcgcagc agcgcgcccg gtgattccgg
    48601 gaattcgaag ctgtagaggc gttcctgcaa cggatgtgac ggacgcccgc cgaccatata
    48661 gcgcacatgc aacttcgcca tttcgtcgtc ggagagatcc accacgctgt agccgccgtc
    48721 gttgagcatc tgcaaaattt ctttgcgctc ttcgaggccg cggctcaggc gcacgccgac
    48781 aaagatgcag gcgtttttgg catcggcaaa acggtagttg aactcggtga ccgatcgccc
    48841 gccaagcagt tggcagaatt tgaggaagct gcctttttct tccggaatgg tcaccgccaa
    48901 caacgcttca cgctgttcgc ccagttcgca gcgttccgag acgtagcgca ggccgtggaa
    48961 gttcacgttg gcaccggaaa gaatatgcgc cagccgttcg ccgcgaatgt tgtgctgggc
    49021 gatatatttt ttcattcccg ccagcgccag cgcgccagag ggttccgcca ccgcgcgcac
    49081 atcttcgaat aaatccttca tcgccgcaca gatcgcatca ctatcgacgg tgatgatgtc
    49141 gtcgagatac tcctggcata aacggaaggt ttcgtcaccg atgcgtttta ccgctacgcc
    49201 ttcagcaaat agccctacgc gcggcagatc aaccggatga cccgcatcca gcgctgcttt
    49261 caggcaggcg gagtcttccg cttctacggc gatcactttg atttgtggca tcagttgttt
    49321 gatcagcacc gcaacgcccg ccgccagacc gccgccgccg actggcacaa atacgcggtc
    49381 gagatgggcg tcctgctgga gcagttccag cgccagcgtg ccttgcccgg caatcaccat
    49441 cggatggtcg aacggcggca cccaggtgaa cccctgctgc tgtgacagtt cgatcgcttt
    49501 agctttcgct tcgtcaaagt tcgcgccatg aagcagcact tcgccgccga atccacgtac
    49561 cgcatcgact ttgatgtcgg cggtggcggt tggcataacg atcagggcct tcacgcctaa
    49621 ccgcgcagaa gaaaacgcga cgccctgcgc gtggttaccc gcagaagcag tgatcacgcc
    49681 gtgcgctttt tgttcttccg tcaggcccgc catcatggcg tatgcgccgc gcagcttaaa
    49741 gctgtgcact ggctggcgat cttcgcgctt caccagaatg acgttatcaa gacgcgacga
    49801 cagtttttcc attttttgta gcggcgtaac ctgcgccgcc tcgtaaaccg gcgcgcgcag
    49861 cactgctctt aaatattcgg caccttccgg agcaccggac aggggttgcg agtcagccat
    49921 tattaacccc ccagtttcga tttatcgcgc accgcacctt tgtcggcgct ggttgccagg
    49981 ctggcgtagg cgcgcagggc aaaggaaacc tgacgttcac ggtttttcgg cgtccaggct
    50041 ttgtcacccc gagcttcctg cgcttcacga cgcgccgcca gttcggcatc gcttacctgt
    50101 aactgaatgc cacggttcgg gatgtcgata gcgatcaggt caccatcttc aatcagacca
    50161 atgctgccgc cgcttgccgc ttccggtgag acgtggccga tggaaagacc agaggtgccg
    50221 ccagagaaac gaccgtcggt gatcagcgca caggctttac cgagacccat tgatttcagg
    50281 aagctggttg ggtagagcat ttcctgcatg ccagggccgc ctttcgggcc ttcatagcgg
    50341 atcaccacca catcgcccgc gacaactttg ccaccgagga tcgcttctac cgcgtcgtcc
    50401 tggctttcgt acactttcgc cgggccggtg aatttgagga tgctgtcatc gacgcccgcg
    50461 gttttaacga tgcagccgtt ttctgcgaaa ttaccgtaga gcaccgccag gccgccgtct
    50521 ttgctgtagg cgtgttccag cgagcggata cagccattgg cgcgatcgtc atcgagagaa
    50581 tcccaacggc aatcctgcga gaatgcctgt gtggtacgaa tgcctgcagg acctgcgcgg
    50641 aacatatttt ttaccgcgtc atcctgggtc agcataacgt cgtattgttc cagcgtttgc
    50701 ggcaacgtca ggccaagtac gtttttcaca tcacggttca gtaaccccgc gcgatccagt
    50761 tcgccgagaa taccgataac accaccagca cggtgaacat cttccatatg gtatttctgg
    50821 gtgctcggcg caactttaca cagctgtgga accttgcggg aaagcttatc gatatcactc
    50881 atggtgaagt cgatttccgc ttcctgcgcc gccgccagca ggtgaagtac ggtgttagtc
    50941 gatccaccca tcgcgatatc cagcgtcatg gcgttttcaa acgccgcttt gctagcaata
    51001 ttgcgcggca gtgcactttc gtcgttttgc tcgtagtaac gtttggtcaa ttcaacaatg
    51061 cgtttaccgg cattgaggaa caactgctta cggtcggcgt gggttgccag cagcgagccg
    51121 ttgcccggct gcgacagacc cagcgcttcg gtcaggcagt tcattgagtt agcggtaaac
    51181 atcccggagc aggagccgca ggtcggacac gcggaacgtt caacctgatc gctctgggag
    51241 tcagaaactt tcgggtctgc gccctggatc atcgcatcaa ccagatcgag tttgattatc
    51301 tgatcggaca gtttggtttt cccggcctcc atcgggccgc cggaaacaaa gatcaccgga
    51361 atattcaggc gcagggaagc catcagcatc cccggggtga ttttgtcgca gttagagatg
    51421 cagaccatgg cgtcggcgca gtgggcgttg accatatact caacggaatc agcgatcagt
    51481 tcgcgagatg gcagtgaata aagcatcccc ccgtggccca tggcaatccc atcatccacc
    51541 gcaatggtgt tgaactcttt ggcaacgccg ccagccgctt caatttgttc ggcgaccagt
    51601 ttaccgagat cgcgcagatg gacgtgaccc ggtacaaatt gggtgaacga gttcacaacc
    51661 gcgataatcg gcttaccgaa atcggcgtcg gtcattccgg tggcgcgcca cagcgcacga
    51721 gcacccgcca tattacgacc atgagtggtg gtggcggaac ggtacttagg catactttat
    51781 ttactcccag tgtctgtctc gtaaatggga cggtgcgtgc cgtcccattt tttgtattta
    51841 ttgattaact tgatctaacc agccccattt atcttcggtt tcgccagtga agaggccgaa
    51901 gaaggcttgc tgaatgcgtt tggtaaccgg gccacaacgg ccttcgccaa cctgaatacc
    51961 gtctacgctg cgcactggcg tgatttctgc cgccgtaccg gacataaaca cttcatccgc
    52021 caggtacagg gattcgcgcg acagaacctg ctcacgcaca tcaattccca gctctttcgc
    52081 cagtttgatg atggcatcac gggtaatacc cggcagcgcg gaggaggtga acggtggggt
    52141 gaacagcaca ccatctttca cttcaaacag gttttcgcct gcgccttcag agatataacc
    52201 gttcacatcc agcgcgatac cttcctgata accgtggcgg cgcgcttcgc tacccaccag
    52261 cagggaagag aggtagttac caccggcttt tgccgccgtc gggatggtgt ttggtgctgc
    52321 gcggttccag gaggaaacca tcgcatcgat cccctgctcc agcgcttctg cgcccagata
    52381 cgctccccac gggaaagcag cgataatcac gtcggttgag tatcccgctg gcgggtttac
    52441 tcccatgcca acatcaccga cgaagatcag cggacggata taggcgctgg tgagattatt
    52501 tttgcggatc acgtcacgac aagcttccat cagctcatca atgctctgtg aaaccgggaa
    52561 gcgatagatt ttggcggagt catgcagacg ctgcatatgc tcacgatggc ggaatacaac
    52621 cggtcctttg tgtgagtcgt agcaacggat gccttcaaaa accgaggtgc catagtgcag
    52681 cgcgtgcgac atcacatgca ccttcgcgtc ttcccagcga accatctccc cattgaacca
    52741 aatgtaatca gctttcttcg tggtcatttt tatattcctt ttgcgctcag gcgcggattt
    52801 gttgtgatgt ggttgtgctc tggcagatgg caacgtgtgc gacgtccacc agtttattta
    52861 actgactaaa cagtaagtcg accgaccgtg ggctggcaac ggtcaattcg atatttatat
    52921 tttgtgcatc gctggcggca gccatattca ttgagcagac gtggaaacca cgatgacgca
    52981 ccacgcgtaa aacacgttct aaggtttccg gattgaagcg agccgataca ttgacctgat
    53041 gttgcatcat gataatttct ccaacatttc tgaattactg gcgccaggcg gcaccagcgg
    53101 ccagacgttc tcaagttcgt cgattgagac atgaagcagg tatggcccat cactgttcag
    53161 catggtgtcg agtgccgctt caacctggtc tttacgggtg atgtgttggc cagggatgcc
    53221 gaaggcgctg gctaacatga ggaaatcggg gttatcagta agggtggttt cgctgtatcg
    53281 ttcctgaaaa aacagttgct gccattgtcg aaccatccct aaccgttggt tatcgagtaa
    53341 gacgattttc aacggtaact gcttgcgttt tacggtgccc agctcttgca cattcatcat
    53401 gaaagagccg tcaccggaga tacagacgac agtatcgttc ggtcgtgcga cttgtgcgcc
    53461 aaccgccgct ggtaaaccga aacccatggt gcctaagccg ctggaggtaa tgaaattttc
    53521 cgggcgagtg tgtgcgatgt gctgcgcggc ccacatctgg tgctgcccca catctgtggt
    53581 cacgacgcaa tccgcaggtt tacgatccga cagttgtttt aacaacaatg gcgcgtagat
    53641 agcgtcaccg ggatggtcgt aacgccaggc atgttcatca cgcagctgcg cgcagtgtag
    53701 ctgccagtca ttgatattta acggctgctg taatgctggt aacagagcat ttaaatcacc
    53761 ttgtaatgcc acatgtgcct gacgcagctt gttcatttct gccgggtcga tatccatatg
    53821 gataacactg gcgtgtggtg cgaaggtgtt cagtttgccg gtcacccggt catcaaaacg
    53881 tgcacccacg gcgatcagca agtcgcactc ctgcaccgcg aagttcgccg ctttggtgcc
    53941 atgcattccc agcatgccca gatagtacgg ataatctgct tcaactgcgc ccagcccttt
    54001 cagcgtgcag gtggcaggca tttttgtggt agcgagaaat tctcgtaaag caggaactgc
    54061 ctgcgccata cccacgccac caccaacgta cagcatcggt ttttgcgctt ttgccagcat
    54121 ctggcgcgct tgctcaactt cggcatgtgg gaaagtcact tcgttttcaa cggtggtgaa
    54181 ccacggttcc aggtcaccgc tggctagctg gatatctttt gggatatcga ccagaaccgg
    54241 accaggacga cctgagctgg caacgtcgaa tgcttcagcc ataatgcgcg gcaactcttc
    54301 cagcgactgc accagaaagc tgtgcttggt acaggctaac gacaatccca ggacatccac
    54361 ttcctgaaat gcgtccgtgc cgataaacgg tgcggacact tgaccggtga tggcaacaac
    54421 agggatagaa tctaacagtg cgtccgcaag cccggttatc aggttggttg cgcccggacc
    54481 agacgtggcg atacatacgc cagttttgcc ggtagcacgg gcataaccga tagccgccat
    54541 tgccgcaccc tgctcatgtc ggcacagcaa gtgctccacg ccgccgtcat acaatgcatc
    54601 gtaaaccggc ataattgcgc cacccggata accgaaaacg gtgttcacac cctgtgcccg
    54661 caacgcatgt accacccact gtgcgccatt catagttagt tccccgtcct gaatcttgag
    54721 aaacagaatt ttgtgctgtt attcattgtc tgctcctcgg ttatgttttt aaggtcaaaa
    54781 aaaacccccg gacctttcgg tgcgggggtc ttagttcgtt aaggcttgat ctctaagcct
    54841 ttcctcgtcc aagtgcagcc ccgcacggtg ggataataat caccaccacg ctaatcacga
    54901 ccaggctaat cactcgtaga agggctgtca ttttgtcttt tcttgcatct tgttcgaagg
    54961 aatgcctaaa gagttaccat agattttgcg aatagcacaa gatatttttt ggccgatttt
    55021 tatgatgcgt ttaataattt caatagaaat tgttgttttt taaaaagaaa atagtgagtg
    55081 aaaaaaaatt caatttcagt atgaatgttg ttcccttcct cgtagttcat cctttgtccg
    55141 ctgcattttt gcgagcatca ttccaccgcc agaacaactc aacttcactt gcacaaataa
    55201 acaggaatca gccactaaaa ttcacgaatt agcgggctac agcagcgata tcttatgcac
    55261 ataatagtga ctcaaggagg gcttatgtca ctgtcaattg ttcatacccg cgcagccctg
    55321 ggagtaaatg cgcccccaat cactgttgag gtacatatca gtaaaggtct acccggctta
    55381 acgatggtgg gcttaccaga aacaactgta aaagaagctc gcgatcgcgt gcgcagcgcc
    55441 attatcaata gcggatatga atatccggcg aaaaaaatca ccatcaacct ggctccagcc
    55501 gatctgccaa aagaaggggg acgatatgat ttacctatcg ccattgcgtt gctggcggcc
    55561 tcagaacagc ttacagccaa taagttagat gaatatgaat tagtcggaga actggcgctt
    55621 acaggcgctc tgcgtggcgt tcccggcgca atctccagtg caactgaagc tattaagtcg
    55681 ggcagaaaaa ttatcgtcgc gaaagataac gaagatgaag tggggctaat taacggtgaa
    55741 ggatgcctga tagccgatca tctgcaggct gtctgtgcgt ttctggaagg taagcacgct
    55801 ctcgaacgcc cgaaaccaac tgatgcagta tcccgggcgc tacaacatga tctcagtgat
    55861 gttgtcggtc aggagcaagg aaagcgagga ctggaaatta ccgccgctgg cgggcacaac
    55921 cttttactga ttgggccgcc gggaacaggt aaaacaatgc tcgccagccg tattaatggc
    55981 ctgttgccag atttaagcaa tgaagaggca ctggagagcg ctgcgatatt aagtctggta
    56041 aatgctgaat cagtacaaaa acaatggcgg cagcgcccgt tccgctcacc gcatcacagt
    56101 gcgtcgttaa ctgcgatggt gggcggtggt gcaattccag ggccaggtga aatttcgttg
    56161 gcgcataacg gcgtgctttt tcttgatgag ctacctgaat ttgaacggcg tacactggat
    56221 gccttgcgag agccgattga atccgggcag atccatcttt cacgcacacg agccaaaata
    56281 acctatccag cccgtttcca gcttgttgcg gcgatgaatc ccagccctac cggacattat
    56341 cagggaaacc ataaccgctg cacgccagaa cagacattac gttatctcaa ccggctctcg
    56401 gggccctttc tcgaccgctt cgatctctca ctggagatcc cattaccacc ccccggcatt
    56461 ttgagtaaaa cggtagtgcc gggagaaagc agcgccaccg ttaaacaacg cgtaatggcc
    56521 gccagagagc gccaatttaa gcggcagaat aaactgaatg cctggctgga tagtccggaa
    56581 atacgccaat tctgcaaact tgagagcgaa gatgcgatgt ggttggaagg aacactgatc
    56641 catctggggt tatcgattcg tgcctggcag cggttattga aagttgcacg aaccattgct
    56701 gatattgatc agtctgacat tatcacacgt cagcatttgc aggaggcagt tagctatcgt
    56761 gcgattgacc gtttgctcat ccatctgcaa aaactactga cataaaaaaa gggcatttcg
    56821 ccctttttat taatcatcag aatcggtgta gtcttcagca ccttcaacct gcggtttacc
    56881 gccggaaagg gtgtgaaaac gttttggacg cttaatacgc gtcatatact tggaccacac
    56941 gcgttctgct tctgtcactg gctcacgttc gccacggcat actgctacga agagtttctc
    57001 ttcctcggta accggctcgc gtttgccaag atccaactca ttgaaggcat aaccatgacg
    57061 ctcaagcagt tgtgcctctt tgatggtgaa atcaccatga cgagagaatc cacgtggata
    57121 atgtttattg tcgaaatatc gattagtcgt cgtaaagctt tccgccatcc tgcacgctcc
    57181 taattctttg accgagctag ttatggcgcg gagtattagt tacgcttgac agagtgtaaa
    57241 acaaaacatt taaatcataa cgacaaataa ttttgcggag agcactgtgg atacggaatt
    57301 gttaaaaact ttcctggaag ttagccgaac gcgtcacttt ggtcgagcgg ctgaatcgct
    57361 ctatctgacc cagtcagcag tgagctttcg aatcagacaa ctggaaaatc aactgggtgt
    57421 gaaccttttc acccgccaca gaaacaatat ccgtttaacc gctgccggtg aaaaactact
    57481 gccttatgca gaaacgctca tgagcacctg gcaggccgcc cgcaaggagg tggcgcatac
    57541 ctcacgacat aacgagtttt ctatcggtgc cagcgcctca ttgtgggaat gtatgcttaa
    57601 tcagtggctg ggacgtttgt atcaaaatca ggatgcccat acaggcttac agttcgaagc
    57661 gcgaattgcc caacggcagt ctctggtaaa acagctgcat gaacgccagc ttgatcttct
    57721 tattaccact gaagcgccca aaatggacga atttagtagt cagttgctgg gatatttcac
    57781 tttagcgctt tataccagtg ccccttcaaa actaaaggga gatcttaatt atctgcgact
    57841 tgagtggggg ccagattttc aacagcatga ggcaggtttg atcggtgctg acgaagtgcc
    57901 cattctgaca accagttctg ctgaactggc acagcaacag attgcgatgc ttaatggttg
    57961 cacctggcta cccgtcagct gggcgcgtaa aaaaggcggc ctgcataccg ttgtcgatag
    58021 cacaacactt tcacggccgc tttatgccat atggctgcaa aatagcgata aaaatacgtt
    58081 gattcgcgat cttttgaaaa ttaacgtgct ggatgaagtg tattaatatg aatggctggc
    58141 aaggatgccg gtagaaggat ttacttcgga gagggttatt tcagataaaa aaaatcctta
    58201 gctttcgcta aggatgattt ctggcagggg cggagagact cgaactccca acacccggtt
    58261 ttggagaccg gtgctctacc aattgaacta cgcccctaat tag
//
LOCUS       DAZUDJ010000025        55608 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.025, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000025 DAZUDJ010000000
VERSION     DAZUDJ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 55608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55608
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.025"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(18..548)
                     /gene="ydeS"
                     /locus_tag="ACHY1N_002090"
     CDS             complement(18..548)
                     /gene="ydeS"
                     /locus_tag="ACHY1N_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4044404.1"
                     /translation="MKYNNIIFLGLCLGLTTYSALSADSVIKISGRVLDYGCTVSSDS
                     LNFTVDLQKNSARQFPTTGSTSPVVPFQITLSECSKGTTGVRVAFNGIEDAENNTLLK
                     LDEGSNTASGLGIEILDANMRPVKLNDLHAGMQWIPLVPEQNNILPYSARLKSTQKSV
                     NPGLVRASATFTLEFQ"
     gene            complement(562..3213)
                     /locus_tag="ACHY1N_002091"
     CDS             complement(562..3213)
                     /locus_tag="ACHY1N_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015473 - fimbrial usher porin activity
                     [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HFS4044405.1"
                     /translation="MTAFRAAFKAYRMHQVLILPRFARLTIALGLATAVFPVDAEYYF
                     NPRFLSNDLAESVDLSAFTKGREAPPGTYRVDIYLNDEFMTSRDITFIADDNNADLIP
                     CLSTDLLVSLGIKKSALLDNKEHSAEKHVPDNSACTPLQDRLADASTEFDVGQQHLSL
                     SVPQIYVGRMARGYVSPELWEEGINAGLLNYSFNGNSINNRSNHNAGKSNYAYLNLQS
                     GINIGSWRLRDNSTWSYNSGSSNSSNSNKWQHINTSAERDIIPLRSRLTVGDSYTDGD
                     IFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIALGTAQVSVKQNGYDVYQTTVPPGP
                     FTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQRAGYTRYALAMGEYRSGN
                     NLQSSPKFIQGSLMHGLEGNWTPYGGMQIAEDYQAFNLGIGKDLGLFGAFSFDITQAN
                     TTLADGTRHSGQSVKSVYSKSFYQTGTNIQVAGYRYSTQGFYNLSDSAYSRMSGYTVK
                     PPTGDTNEQTQFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASRQSYWNTSRSDQQ
                     ISFGLNVPIGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRNSNA
                     SYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYSSLNYRGAY
                     GNTNVGYSRNGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNVKIENQT
                     GIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQ
                     IGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGKDK
                     NSNCIVEYKLPEVSPGTLLNQQTAICR"
     gene            complement(3255..3965)
                     /locus_tag="ACHY1N_002092"
     CDS             complement(3255..3965)
                     /locus_tag="ACHY1N_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HFS4044406.1"
                     /translation="MQTTRTPYSISFMATVLLLLLFACHSTVANAAVALGATRVIYPA
                     NQKQVLLPVTNNDPASVYLIQSWIENAGDQKDTQFVITPPLFSMQGKKENTLRIINAT
                     NHQLPGDRESLFWVNVKAIPAMEKDQKNENTLQLAIISRIKMFYRPTNLAMAPEEAPA
                     MLRFRRSGSKLTLINPTPYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAATGDISF
                     QTINDYGALTPRIKATMQ"
     gene            complement(4128..4232)
                     /locus_tag="ACHY1N_002093"
                     /pseudo
     CDS             complement(4128..4232)
                     /locus_tag="ACHY1N_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310140.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4664..4872)
                     /locus_tag="ACHY1N_002094"
                     /pseudo
     CDS             complement(4664..4872)
                     /locus_tag="ACHY1N_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226947.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(5184..6506)
                     /gene="hipA"
                     /locus_tag="ACHY1N_002095"
     CDS             complement(5184..6506)
                     /gene="hipA"
                     /locus_tag="ACHY1N_002095"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system serine/threonine
                     protein kinase toxin HipA"
                     /protein_id="HFS4044407.1"
                     /translation="MPKLVTWMNNQRVGELTKLANGAHTFKYAPEWLASRYARPLSLS
                     LPLQRGNITSDAVFNFFDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVT
                     LLPENETITRPIMAWEKLTEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTAL
                     LRIGNDWCIPKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVP
                     DAEIIKAGRVRALAVERFDRRWNTERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIA
                     RIMAFLMGSSEALRDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDII
                     SAFPVLGGTGIHISDLKLAMGLNASKGKKTAIDKIYPRHFLATAKVLRFPEVQMHEIL
                     SDFARMIPAALDNVKTSLPTDFPENVVTAVETNVLRLHGRLSREYGSK"
     gene            complement(6506..6772)
                     /gene="hipB"
                     /locus_tag="ACHY1N_002096"
     CDS             complement(6506..6772)
                     /gene="hipB"
                     /locus_tag="ACHY1N_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HipB"
                     /protein_id="HFS4044408.1"
                     /translation="MMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISN
                     FENNPDNTTLTTFFKILQSLELSMTLCDTKNASPESTEQQDLEW"
     gene            complement(6981..12401)
                     /locus_tag="ACHY1N_002097"
     CDS             complement(6981..12401)
                     /locus_tag="ACHY1N_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECSE_1600 family autotransporter"
                     /protein_id="HFS4044409.1"
                     /translation="MNRIYRVIWNCTLQVFQACSELTRRAGKTSTVNLRKSSGLTTKF
                     SRLTLGVLLALSGSASGASLEVDNDQITNIDTDVAYDAYLVGWYGTGVLNILAGGNAS
                     LTTITTSVIGANEDSEGTVNVLGGTWRLYDSGNNARPLNVGQSGTGTLNIKQKGHVDG
                     GYLRLGSSTGGVGTVNVEGEDSVLTTELFEIGSYGTGSLNITDKGYVTSSIVAILGYQ
                     AGSNGQVVVEKGGEWLIKNNDSSIEFQIGNQGTGEATIREGGLITAENTIIGGNATGV
                     GTLNVQDQDSVITVRRLYNGYFGNGTLNISNNGLINNKEYSLVGVQDGSHGVVNVTDK
                     GHWNFLGTGEAFRYIYIGDAGDGELNVSREGKVDSGIITAGMKETGTGNITVKDKNSV
                     ITNLGTNLGYDGHGEMNISNEGLVVSNGGSSLGYGETGVGNVSITTGGMWEVNKNVYT
                     TIGVAGVGNLNISDGGKFVSQNITFLGDKASGIGTLNLMDATSSFDTVGINVGNFGSG
                     IVNVSNGATLNSTGYGFIGGNASGKGIVNISTDSLWNLKTSSTNAQLLQVGVLGKGEL
                     NITTGGIVKARDTQIALNDKSKGDVRVDGQNSLLETFNMYVGTSGTGTLTLTNSGTLN
                     VEGGEVYLGVFEPAVGTLNIGAAHGEAAADAGYITNATKVEFGSGEGVFVFNHTNNSD
                     AGYQVDMLITGDDKDGKVIHDAGHTVFNAGNTYSGKTLVNDGLLTIASHTADGVTGMG
                     SSEVTIASPGTLDILASTNSAGDYTLTNALKGDGLMRVQLSSYDKMFGFTHATGTEFA
                     GVAQLKDSTFTLERDNTAALTHAMLQSDSENTTSVKVGEQSIGGLAMNGGTLIFDTDI
                     PAATLAEGYISVDTLVVGAGDYTWKGRNYQVNGTGDVLIDVPKPWNDPMANNPLTTLN
                     LLEHDDSHVGVQLVKAQTVIGSGGSLTLRDLQGDEVEADKTLHIAQNGTVVAEGDYGF
                     RLTTAPGDGLYVNYGLKALNIHGGQKLTLAEHGGAYGATADMSAKIGGEGDLAINTVR
                     QVSLSNGQNDYQGATYVQMGTLRTDADGALGNTRELNISNAAIVDLNGSTQTVETFTG
                     QMGSTVLFKEGALTVNKGGISQGELTGGGNLNVTGGTLAIEGLNARYNALTSISPNAE
                     VSLDNTQGLGRGNIANDGLLTLKNVTGELRNSISGKGIVSATARTDVELDGDNSRFVG
                     QFNIDTGSALSVNEQKNLGDASVINNGLLTISTERSWAMTHSISGSGDVTKLGTGILT
                     LNNDSAAYQGTTDIVGGEIAFGSDSAINMASQHINIHNSGVMSGNVTTAGDVNVMPGG
                     TLRVAKTTIGGNLENGGTVQMNSEGGKPGNVLTVNGNYTGNNGLMTFNATLGGDNSPT
                     DKMNVKGDTQGNTRVRVDNIGGVGAQTVNGIELIEVGGNSAGNFALTTGTVEAGAYVY
                     TLAKGKGNDEKNWYLTSKWDGVTPPDTPDPINNPPVVDPEGPSVYRPEAGSYISNIAA
                     ANSLFSHRLHDRLGEPQYIDSLHSQGSASSMWMRHVGGHERSRAGDGQLNTQANRYVL
                     QLGGDLAQWSSNAQDRWHLGVMAGYANQHSNTQSNRVGYKSDGRISGYSAGLYATWYQ
                     NDANKTGAYVDSWALYNWFDNSVSSDNRSADDYDSRGVTASVEGGYTFEAGTFSGSEE
                     TLNTWYVQPQAQITWMGVKDSDHTRKDGTRIETEGDGNVQTRLGVKTYLNSHHQRDDG
                     KQREFQPYIEANWINNSKVYAVKMNGQTVGREGARNLGEVRTGVEAKVNNNLSLWGNV
                     GVQLGDKGYSDTQGMLGVKYSW"
     gene            complement(12932..14524)
                     /gene="lsrK"
                     /locus_tag="ACHY1N_002098"
     CDS             complement(12932..14524)
                     /gene="lsrK"
                     /locus_tag="ACHY1N_002098"
                     /EC_number="2.7.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416028.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071518 - autoinducer-2 kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer-2 kinase"
                     /protein_id="HFS4044410.1"
                     /translation="MARLFTPSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWR
                     HLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNNE
                     GAPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSD
                     IYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADIL
                     SPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTF
                     WQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAE
                     RLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKAT
                     LFRALEENAAIVSACNLQQIADFSNIHPTSLVFAGGGSKGKLWSQILADVSGLPVNIP
                     VVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPDPEKHELYQDSRDKWQAV
                     YQDQLGLVDHGLTTSLWKAPGL"
     gene            complement(14603..15556)
                     /gene="lsrR"
                     /locus_tag="ACHY1N_002099"
     CDS             complement(14603..15556)
                     /gene="lsrR"
                     /locus_tag="ACHY1N_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LsrR"
                     /protein_id="HFS4044411.1"
                     /translation="MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTR
                     LKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRL
                     GIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
                     GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDD
                     ATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTDIKIHNELIGLPLSSLKTI
                     PVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS"
     gene            15805..17340
                     /gene="lsrA"
                     /locus_tag="ACHY1N_002100"
     CDS             15805..17340
                     /gene="lsrA"
                     /locus_tag="ACHY1N_002100"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter ATP-binding
                     protein LsrA"
                     /protein_id="HFS4044412.1"
                     /translation="MQTSDTRALPLLCARSVYKQYSGVNVLKGIDFTLHQGEVHALLG
                     GNGAGKSTLMKIIAGITPADSGTLEIGGNNYARLTPVHAHQLGIYLVPQEPLLFPSLS
                     IKENILFGMAKKQLSMQKMKNLLAALGCQFDLHSLAGSLDVADRQMVEILRGLMRDSR
                     ILILDEPTASLTPAETERLFTRLQELLATGVGIVFISHKLPEIRQIADRISVMRDGTI
                     ALSGKTSELSTDDIIQAITPAVREKSLSASQKLWLELPGNRPQHAAGTPVLTLENLTG
                     EGFRNVSLTLNAGEILGLAGLVGAGRTELAETLYGLRTLRGGRIMLNGKEINKLSTGE
                     RLLRGLVYLPEDRQSSGLNLDASLAWNVCALTHNLRGFWAKTAKDNATLERYRRALNI
                     KFNQPEQAARTLSGGNQQKILIAKCLEASPQVLIVDEPTRGVDVSARNDIYQLLRSIA
                     AQNVAVLLISSDLEEIELMADRVYVMHQGEIAHSALTGRDINVETIMRVAFGDSQRQE
                     VSC"
     gene            17334..18362
                     /gene="lsrC"
                     /locus_tag="ACHY1N_002101"
     CDS             17334..18362
                     /gene="lsrC"
                     /locus_tag="ACHY1N_002101"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrC"
                     /protein_id="HFS4044413.1"
                     /translation="MLKFIQNNREITALLAVVLLFALPGFLDRQYLSVQTLTMVYSSA
                     QILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLA
                     GFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVS
                     AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMA
                     ALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQID
                     SVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKYARFMTPPPSVKPAS
                     SGKKREAA"
     gene            18362..19354
                     /gene="lsrD"
                     /locus_tag="ACHY1N_002102"
     CDS             18362..19354
                     /gene="lsrD"
                     /locus_tag="ACHY1N_002102"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrD"
                     /protein_id="HFS4044414.1"
                     /translation="MRIRYGWELALAALLVIEIVAFGAINPRMLDLNMLLFSTSDFIC
                     IGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGL
                     INAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
                     LGLPVPLIIFLICLLVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMT
                     GLASAVAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLV
                     GYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEWLARRANNPLP"
     gene            19366..20388
                     /gene="lsrB"
                     /locus_tag="ACHY1N_002103"
     CDS             19366..20388
                     /gene="lsrB"
                     /locus_tag="ACHY1N_002103"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein LsrB"
                     /protein_id="HFS4044415.1"
                     /translation="MTLHRFKKIALLSALGIAAISMNVQAAERIAFIPKLVGVGFFTS
                     GGNGAQQAGKELSVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPAL
                     KRAMQRGVRVLTWDSDTKPECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYS
                     SPTVTDQNQWVKEAKAKIAKEHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAII
                     APDANALPAAAQAAENLKNDKVAIVGFSTPNVMRPYVERGTVKEFGLWDVVQQGKISV
                     YVADALLKKGSMKTGDKLDIQGVGQVEVSPNSVQGYDYEADGNGIVLLPERVIFNKEN
                     IGKYDF"
     gene            20415..21290
                     /gene="lsrF"
                     /locus_tag="ACHY1N_002104"
     CDS             20415..21290
                     /gene="lsrF"
                     /locus_tag="ACHY1N_002104"
                     /EC_number="2.3.1.245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /protein_id="HFS4044416.1"
                     /translation="MADLDDIKDGKDFRTDQPQQNIPFILKGCGALDWGMQSRLSRIF
                     NPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNK
                     PVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLV
                     DAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGAQIIKTYYVEKGFERIVAGC
                     PVPIVIAGGKKLPEREALEMCWQAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHN
                     ETADRAYELYLSEKQ"
     gene            21314..21604
                     /gene="lsrG"
                     /locus_tag="ACHY1N_002105"
     CDS             21314..21604
                     /gene="lsrG"
                     /locus_tag="ACHY1N_002105"
                     /EC_number="5.3.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione
                     isomerase"
                     /protein_id="HFS4044417.1"
                     /translation="MHVTLVEINVHEDKIDEFIEVFRQNHLGSVQEEGNLRFDVLQDP
                     EVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLESLMTGPRKKRLFNGLMP"
     gene            21661..22419
                     /gene="tam"
                     /locus_tag="ACHY1N_002106"
     CDS             21661..22419
                     /gene="tam"
                     /locus_tag="ACHY1N_002106"
                     /EC_number="2.1.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030798 - trans-aconitate
                     2-methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="HFS4044418.1"
                     /translation="MSDWNPSLYLHFAAERSRPAVELLARVPLENIEYVADLGCGPGN
                     STALLNQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPEQALDLIFANAS
                     LQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLA
                     GVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFL
                     KRYHQMLEEQYPLQENGQILLAFPRLFIVARRME"
     gene            complement(22423..23337)
                     /gene="yneE"
                     /locus_tag="ACHY1N_002107"
     CDS             complement(22423..23337)
                     /gene="yneE"
                     /locus_tag="ACHY1N_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family protein"
                     /protein_id="HFS4044419.1"
                     /translation="MIVRPQQHWLRRIFVWHGSVLSKISSRLLLHFLFSIAVIFMLPW
                     YTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKT
                     TLPDSASVREFARLQIAFAHCLRMTLRKQPQAEVLAHYLKTEDLQPVLASNSPANRIL
                     LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFISLDCLAEELEDPFGTENNDLPLDAICN
                     AIEIDLLQMNDEAEIPAKILPDRHYQLT"
     gene            complement(23544..24995)
                     /gene="uxaB"
                     /locus_tag="ACHY1N_002108"
     CDS             complement(23544..24995)
                     /gene="uxaB"
                     /locus_tag="ACHY1N_002108"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFS4044420.1"
                     /translation="MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDL
                     NSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEY
                     DEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGA
                     LDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTG
                     YPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKP
                     YKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRD
                     ELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFA
                     LAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWE
                     QDLTQVPGLVEQVANDLDAILEKGMREAVRPLC"
     gene            complement(25222..26640)
                     /locus_tag="ACHY1N_002109"
     CDS             complement(25222..26640)
                     /locus_tag="ACHY1N_002109"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HFS4044421.1"
                     /translation="MHVHPISTFRLFQEGHLLRNSIAIFALTTLFYFIGAELRLVHEL
                     SLFWPLNGVMAGVFARYVWLNRLHYYAISYVAMLVYDAITTEWGLVSLVINFSNMMFI
                     VTVALLVVRDKRLGKNKYEPVSALRLFNYCLIAALLCAIVGAIGSVSIDSLDFWPLLA
                     DWFSEQFSTGVLIVPCMLTLAIPGVLPRFKAEQMMPAIALIVSVIASVVIGGAGSLAF
                     PLPALIWCAVRYTPQVTCLLTFVTGAVEIVLVANSVIDISVGSPFSIPEMFSARLGIA
                     TMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYSRSGLYEALKSPSLKQTQHLTV
                     MLLDIDYFKSINDNYGHECGDKVLSVFARHIQKIVGDKGLVARMGGEEFAVAVPSVNP
                     VDGLLMAEKIRKGVELQPFTWQQKTLYLTVSIGVGSGRASYRTLTDDFNKLMVEADTC
                     LYRSKKDGRNRTSTMRYGEEVV"
     gene            complement(26779..27138)
                     /gene="yneG"
                     /locus_tag="ACHY1N_002110"
     CDS             complement(26779..27138)
                     /gene="yneG"
                     /locus_tag="ACHY1N_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HFS4044422.1"
                     /translation="MQSLDPLFARLSRSKFRSRFRLGMKERQYCLEKGAPVIEQHAAD
                     FVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHNIPQGVSLSEEQQR
                     YIVAVIYHWLVVQMNQP"
     gene            complement(27138..28064)
                     /gene="glsB"
                     /locus_tag="ACHY1N_002111"
     CDS             complement(27138..28064)
                     /gene="glsB"
                     /locus_tag="ACHY1N_002111"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HFS4044423.1"
                     /translation="MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIA
                     ICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKA
                     IHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY"
     gene            complement(28128..29516)
                     /gene="sad"
                     /locus_tag="ACHY1N_002112"
     CDS             complement(28128..29516)
                     /gene="sad"
                     /locus_tag="ACHY1N_002112"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004030 - aldehyde dehydrogenase [NAD(P)+]
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HFS4044424.1"
                     /translation="MTITPATHAISINPATGEQLSVLPWAGANDIENALQLAAAGFRD
                     WRETNIDYRAEKLRGIGKALRARSEEMAQMITREMGKPINQARAEVAKSANLCDWYAE
                     HGPAMLKAEPTLVENQQAVIEYRPLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLK
                     HAPNVMGCAQLIAQVFKDAGIPQGVYGWLNADNDGVSQMIKDSRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFII
                     EEGIASAFTERFVAAAAALKMGDPRDEENALGPMARFDLRDELHHQVEKTLAQGARLL
                     LGGEKMAGAGNYYPPTVLANVTPEMTAFREEMFGPVAAITVAKDAEHALELANDSEFG
                     LSATIFTTDETQARQMAARLECGGVFINGYCASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNIQTVWKDRI"
     gene            29617..30498
                     /gene="yneJ"
                     /locus_tag="ACHY1N_002113"
     CDS             29617..30498
                     /gene="yneJ"
                     /locus_tag="ACHY1N_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4044425.1"
                     /translation="MDLTQLEMFNAVAEAGSITQAAAIVHRVPSNLTTRLRQLETELG
                     VDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAV
                     RIPATLAEFNHRYPKIQFSLSTGPSGTMLEGVLEGKLNAAFIDGPINHTAIDGIPVYR
                     EELMIVTPQGHAPVIRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESY
                     HGMLACVVAGAGIALIPRSMLESMPGHHQVEAWPLAEQWRWLTTWLVWRRGAKTRPLE
                     AFIQLLDVSDSAKQSYQ"
     gene            30575..31689
                     /gene="yneK"
                     /locus_tag="ACHY1N_002114"
                     /pseudo
     CDS             30575..31689
                     /gene="yneK"
                     /locus_tag="ACHY1N_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416044.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein YneK"
     gene            31839..33029
                     /gene="ydeA"
                     /locus_tag="ACHY1N_002115"
     CDS             31839..33029
                     /gene="ydeA"
                     /locus_tag="ACHY1N_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose MFS transporter"
                     /protein_id="HFS4044426.1"
                     /translation="MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFH
                     MQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFT
                     VLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIV
                     GQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLT
                     VVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGSGIIGSVIFGKLGNQYASAL
                     VSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLE
                     EQTQ"
     gene            complement(33054..33719)
                     /gene="marC"
                     /locus_tag="ACHY1N_002116"
     CDS             complement(33054..33719)
                     /gene="marC"
                     /locus_tag="ACHY1N_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter MarC"
                     /protein_id="HFS4044427.1"
                     /translation="MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     LMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSP
                     EAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
                     PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIK
                     TYH"
     gene            33931..34365
                     /gene="marR"
                     /locus_tag="ACHY1N_002117"
     CDS             33931..34365
                     /gene="marR"
                     /locus_tag="ACHY1N_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310164.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HFS4044428.1"
                     /translation="MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFK
                     VLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTT
                     SGAAICEQCHQLVGQDLHQELTKKLTADEVATLEHLLKKVLP"
     gene            34385..34768
                     /gene="marA"
                     /locus_tag="ACHY1N_002118"
     CDS             34385..34768
                     /gene="marA"
                     /locus_tag="ACHY1N_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HFS4044429.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRMTNMQGESRFLHPLNHYNS"
     gene            34800..35018
                     /gene="marB"
                     /locus_tag="ACHY1N_002119"
     CDS             34800..35018
                     /gene="marB"
                     /locus_tag="ACHY1N_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HFS4044430.1"
                     /translation="MKPLSSAIAAALILFSAQGVAEQTTQPVVTSCANVVVVPPSQEQ
                     PPFDLNHMGTGSDKSDALGVPYYNQHAM"
     gene            complement(35075..36514)
                     /locus_tag="ACHY1N_002120"
     CDS             complement(35075..36514)
                     /locus_tag="ACHY1N_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFS4044431.1"
                     /translation="MSGFKKGFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVP
                     REVTEGVIDGLNYPNHEAIDFYHRYKTDIQLFAEMGFKCFRTSIAWTRIFPQGDEQEP
                     NEEGLQFYDDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIRFASTV
                     FTRYKEKVKYWMTFNEINNQVNFSESLCPFTNSGILYSPEEDINEREQIMYQAVHYEL
                     VASALAVQTGKSINPEFNIGCMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHTRG
                     YYPQHMLNYFARKGFNLDITPEDNAILASGCVDFIGFSYYMSFTTQFSPDNPQLDYVE
                     PRDLVSNPYIDTSEWGWQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADGTV
                     NDHYRIDYFASHIREMKKAVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKD
                     NEGKGTLERIRKASFYWYRDLIANNGENI"
     gene            complement(36539..38212)
                     /locus_tag="ACHY1N_002121"
     CDS             complement(36539..38212)
                     /locus_tag="ACHY1N_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HFS4044432.1"
                     /translation="MNIKTLNVSLLSFSIITALFPLNAMATKLTIEQRLELLENELSQ
                     NKQELKATQNELGVYKSRLSTLQKSITENKYKSASLAEISATSPVADNIKNENGEQNS
                     FTAAHTINGSQQVAVIESKGDKTTIESVTLKDISKYIKDDIGFSYQGYFRSGWGTGNH
                     GSPQTYAAGSLGRFGNEMSGWFDLTLNQRVYNQDGKTANAVVTYDGNVGEQYNDAWFG
                     DSANENIMQFSDIYLTTRGFLPFAPEADFWVGKHKLPQYEIQMLDWKTLTTDVAAGVG
                     IENWALGVGLFDMSLSRDDVDVYSRDFSRTSQMNTNSVDVRYRNIPLWDDATLSLMAK
                     YSAPNKTDQQQDNENDNSYFEMKDSWMLTSVLRQNLQRDTFNEFTLQVANNSYASSFA
                     SFSDASNTMAHGRYYYGDHTNGIAWRLISQGEMYLTDNIIMANALVYSHGEDVYSYES
                     GAHSDFDSIRTVIRPAWIWNTWNQTGLELGWFKQQNKTQQGVTLNESAYKTTLWHALK
                     VGESILGSRPEIRFYGTYINILDNELSNFKFNENSKDEFMAGIQAEVWW"
     gene            complement(38268..38579)
                     /locus_tag="ACHY1N_002122"
     CDS             complement(38268..38579)
                     /locus_tag="ACHY1N_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFS4044433.1"
                     /translation="MFADEELVMELLVNAGQARSDAMEAIRCAGQKDWQGATQLMASS
                     ESACLQAHKIQTALISQDEGCGKIKVNLILIHAQDHLMNAILCQDLAREIISLRKELH
                     A"
     gene            complement(38607..39929)
                     /locus_tag="ACHY1N_002123"
     CDS             complement(38607..39929)
                     /locus_tag="ACHY1N_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001736301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4044434.1"
                     /translation="MGLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMA
                     SSLIILINFAILSPDGFIAGLLHLNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVA
                     RNMAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALIT
                     SEIFCRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLN
                     DLIYTLIQTPLKHMGTNIFAVIILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENL
                     SWAAQHGTTWGAPYPITWTSINDAFANCGGSGMTLGLLLAIFIASKRAEYRDLAKMSF
                     IPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTT
                     PGPLIAFLGTGGNWLALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG"
     gene            complement(40044..40355)
                     /locus_tag="ACHY1N_002124"
     CDS             complement(40044..40355)
                     /locus_tag="ACHY1N_002124"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4044435.1"
                     /translation="MKKILLVCAAGMSTSMLVKRMIDHANAISLEVNISALAIAEAKG
                     KIKNNEVDVVLLGPQVRFQKPEIEAVAQGKMPVAVIEMKDYGTMNGQAVLEFAMKLLQ
                     E"
     gene            40554..41252
                     /locus_tag="ACHY1N_002125"
     CDS             40554..41252
                     /locus_tag="ACHY1N_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4044436.1"
                     /translation="MIFQKIARLLKSEINGNSWHVGDLLPSEAELAVRYNVSRNTLRK
                     ALSLLEGEGIIHRKHGSGTYIQKKNFVAHIDHMNSFSEIAHKSGKEAGSQIMKFEVQD
                     ASPTIATELNLVTGEQVYYIKRLRFIEDNAAQLEETWMSVARFPDLTVSHMQKSKFSY
                     IENECGIKIIGTFETFSPTFPTPEIASILRISPRDPILKIQTQAVDSNSIPLDYSLLY
                     SNIFEFQVKYFFPR"
     gene            complement(41297..42196)
                     /gene="eamA"
                     /locus_tag="ACHY1N_002126"
     CDS             complement(41297..42196)
                     /gene="eamA"
                     /locus_tag="ACHY1N_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
                     /protein_id="HFS4044437.1"
                     /translation="MSRKDGVLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVA
                     FPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVLQAQAFFTIV
                     LGACTFGERLHGKQLAGIALAIFGVLVLIEDSLNGQHVAMLGFMLTLAAAFSWACGNI
                     FNKKIMSHSTRPAVMSLVIWSALIPIIPFFVASLILDGSASMIHSLVTIDMTTILSLM
                     YLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFLGAV
                     LIMTGLYINVFGLRWRKAVKVRG"
     gene            42391..43578
                     /gene="ydeE"
                     /locus_tag="ACHY1N_002127"
     CDS             42391..43578
                     /gene="ydeE"
                     /locus_tag="ACHY1N_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HFS4044438.1"
                     /translation="MNLSLRRSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDL
                     IGYAMTIALTIGVVFSLGFGILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLF
                     FALINCAYSVFATVLKAWFADNLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI
                     NLPFWLAAICSAFPMLFIQIWVKRSEKIIATETGSVWSPKVLLQDKALLWFTCSGFLA
                     SFVSGAFASCISQYVMVIADGDFAEKVVAVVLPVNAAMVVTLQYSVGRRLNPANIRAL
                     MTAGTLCFVIGLVGFIFSGNSLLLWGMSAAVFTVGEIIYAPGEYMLIDHIAPPGMKAS
                     YFSAQSLGWLGAAINPLVSGVVLTSLPPSSLFVILALVIIAAWVLMLKGIRARPWGQP
                     ALC"
     gene            43705..43800
                     /gene="mgtS"
                     /locus_tag="ACHY1N_002128"
     CDS             43705..43800
                     /gene="mgtS"
                     /locus_tag="ACHY1N_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HFS4044439.1"
                     /translation="MLGNMNVFMAVLGIILFSGFLAAYFSHKWDD"
     gene            43800..43904
                     /gene="mgtT"
                     /locus_tag="ACHY1N_002129"
     CDS             43800..43904
                     /gene="mgtT"
                     /locus_tag="ACHY1N_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtT"
                     /protein_id="HFS4044440.1"
                     /translation="MNGDNPSPNRPLVTVVYKGPDFYDGEKKPPVNRR"
     gene            complement(44019..44909)
                     /gene="dgcZ"
                     /locus_tag="ACHY1N_002130"
     CDS             complement(44019..44909)
                     /gene="dgcZ"
                     /locus_tag="ACHY1N_002130"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcZ"
                     /protein_id="HFS4044441.1"
                     /translation="MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEIT
                     DNHSYGLCQFGRWIDHLGPLDNDELPYVRLMDSAHQHMHNCGRELMLAIVENHWQDAH
                     FDAFQEGLLSFTSALTDYKIYLLTIRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLY
                     LMLLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKAAN
                     DEEACRAGVRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRAMYEG
                     KQTGRNRCMFIDEQNVINRV"
     gene            complement(45164..45556)
                     /gene="ydeI"
                     /locus_tag="ACHY1N_002131"
     CDS             complement(45164..45556)
                     /gene="ydeI"
                     /locus_tag="ACHY1N_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI family stress tolerance OB fold protein"
                     /protein_id="HFS4044442.1"
                     /translation="MKFQAIVLASFLVMPYALADDQGGLKQDAAPPPPHAIEDGYRGT
                     DDAKKMTVDFAKNMHDGASVSLRGNLISHKGEDRYVFRDKSGEINVVIPAAVFDGREV
                     QPDQMINISGSLDKKSAPAVVRVTHLQK"
     gene            45832..46350
                     /gene="ydeJ"
                     /locus_tag="ACHY1N_002132"
     CDS             45832..46350
                     /gene="ydeJ"
                     /locus_tag="ACHY1N_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-tetronate isomerase"
                     /protein_id="HFS4044443.1"
                     /translation="MNINRDKIVQLVDTDTIENLTSALSQRLIADQLRLTTAESCTGG
                     KLASALCAAEDTPKFYGAGFVTFTDQAKMKILSVSQQSLERYSAVSEKVAAEMATGAI
                     ERADADVSIAITGYGGPEGGEDGTPAGTVWFAWHIKGQNYTAVMHFAGDCETVLALAV
                     RFALAQLLQLLL"
     gene            complement(46394..48439)
                     /gene="dcp"
                     /locus_tag="ACHY1N_002133"
     CDS             complement(46394..48439)
                     /gene="dcp"
                     /locus_tag="ACHY1N_002133"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707439.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HFS4044444.1"
                     /translation="MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIA
                     AIALNPQTPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAEL
                     ANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKV
                     LNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAVAAREKGLDNKWL
                     IPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDGNDTRAIIQRLVEIRAQQAKLL
                     GFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQP
                     WDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYH
                     PDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNETHPVIYNVCNYQ
                     KPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHW
                     ATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEE
                     NEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADD
                     GYQWFVEQGGLTRENGQRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQHRGLNI"
     gene            48576..49322
                     /gene="ydfG"
                     /locus_tag="ACHY1N_002134"
     CDS             48576..49322
                     /gene="ydfG"
                     /locus_tag="ACHY1N_002134"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HFS4044445.1"
                     /translation="MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDEL
                     GDNLYIAQLDVRNRAAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETM
                     IDTNNKGLVYMTRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
                     LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWW
                     VSTLPAHVNINTLEMMPVTQSYAGLNVHRQ"
     gene            49411..50097
                     /gene="rspR"
                     /locus_tag="ACHY1N_002135"
                     /gene_synonym="ydfH"
     CDS             49411..50097
                     /gene="rspR"
                     /locus_tag="ACHY1N_002135"
                     /gene_synonym="ydfH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator rspR"
                     /protein_id="HFS4044446.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAA
                     SMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLK
                     ATVDRVRYMSFDHVSPPEMLLRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIR
                     QENSDWFSEE"
     gene            50275..50478
                     /gene="ydfZ"
                     /locus_tag="ACHY1N_002136"
     CDS             50275..50478
                     /gene="ydfZ"
                     /locus_tag="ACHY1N_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HFS4044447.1"
                     /translation="MTTYDRNRNAITTGSRVMVSGTGHTGKILSIDTEGLTAEQIRRG
                     KTVVVEGCEEKLAPLDLIRLGMN"
     gene            complement(50514..51974)
                     /gene="ydfI"
                     /locus_tag="ACHY1N_002137"
                     /pseudo
     CDS             complement(50514..51974)
                     /gene="ydfI"
                     /locus_tag="ACHY1N_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707435.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
     gene            complement(52063..53346)
                     /gene="ydfJ"
                     /locus_tag="ACHY1N_002138"
                     /pseudo
     CDS             complement(52063..53346)
                     /gene="ydfJ"
                     /locus_tag="ACHY1N_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582800.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter YdfJ"
     gene            53478..53720
                     /locus_tag="ACHY1N_002139"
     CDS             53478..53720
                     /locus_tag="ACHY1N_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI-like family protein"
                     /protein_id="HFS4044448.1"
                     /translation="MPHRYPAAKINKMPKGSVPALQQEMLRRVSKRYDDAEVIIKSTS
                     NNGLSVTHTADKDSAKTFVQETLKDTRESADEWFVR"
     gene            complement(53829..53986)
                     /locus_tag="ACHY1N_002140"
                     /pseudo
     CDS             complement(53829..53986)
                     /locus_tag="ACHY1N_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701877.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4376 domain-containing protein"
     gene            54315..54965
                     /gene="nleG7"
                     /locus_tag="ACHY1N_002141"
     CDS             54315..54965
                     /gene="nleG7"
                     /locus_tag="ACHY1N_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001121226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector NleG7"
                     /protein_id="HFS4044449.1"
                     /translation="MPIFLNFTAGSILPENELASLRYIVQQNQNDTVIIKERYKMDIR
                     YIESVNGFTVNPVCSNHFSIFMARQNTIARNLEQQINNGRSFAQISQDFMLQLSSNIG
                     WKKGAENALKNKIHSHSFVVNPDEFSCDTQFLKCPITLCVPEKGVFVKNALNSNICTL
                     YDKSAFMNLTREHLPHPLSREKIVKEMIIERNMCYFDTISQHFIIMDADQQKQHCK"
     gene            complement(55190..>55608)
                     /locus_tag="ACHY1N_002142"
     CDS             complement(55190..>55608)
                     /locus_tag="ACHY1N_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="secretion protein EspS"
                     /protein_id="HFS4044450.1"
                     /translation="CGDEFLSPTDIVDRIVQHNLHEIDDIRLTSCNSANILKNKDFSP
                     DEIEKSANMNNGWLARALFGQKSSLAEHVYAEFERRGINVSISGYHGTGVFYVPEHGK
                     PTTHLRSTTVPATPEHTVRRSDYRATLGRTQPIDIE"
BASE COUNT        14606 a        13784 c        12540 g        14678 t
ORIGIN      
        1 ttcatatctg actctgatta ttgaaattca agggtaaagg ttgccgaagc cctcaccagt
       61 cccggattga cggacttctg agttgacttc agacgagcgg agtaaggcaa aatattgttc
      121 tgttctggta ccagtgggat ccactgcatc ccggcatgaa ggtcattcag tttcaccgga
      181 cgcatatttg cgtccaatat ttctataccc aaaccggagg ccgtattgct tccttcatcc
      241 agtttcaaca aagtattatt ttctgcatcc tcaataccgt taaatgcaac ccgaaccccc
      301 gttgtccctt tgctgcattc acttaacgta atctgaaaag ggacgactgg acttgtgcta
      361 ccggtcgttg gaaattgtct ggcactgttt ttttggagat ctacggtaaa attaagcgaa
      421 tccgatgaga ctgtgcagcc ataatcgagg acgcgcccgc taattttaat aacgctatct
      481 gcggataaag cagaataggt ggttaacccc agacataaac cgaggaaaat aatgttattg
      541 tatttcataa tctattgttc cttagcgaca gattgctgtc tgctggttca gtaaggtacc
      601 aggagaaact tcaggaagct tgtactcgac aatacagttt gagtttttat ctttgcccca
      661 tgaaacctgt aatttccctg actgtggaag tccagtcaga taaacctgac cgttttctgc
      721 gacaatgctg ccatttttat tctctccgtg tgtgacaatt gcaccgaatg gaacgctctt
      781 attaccgtac ttcaacgtca ttaatacttt cccgccgatt tgtgcattaa atgttgctct
      841 ggcaatagca ccgtgagttg ggatgacagt gaccacggtt tcatccagtt caacattatc
      901 tgcaagggaa ttcgcgttaa gagcaacacg gttttctcta tattctgtcg caaatggtaa
      961 tatggcatag ccacgccagt cggtatgaat tccggtctgg ttctctattt tgacattatc
     1021 agcgccagga gccttaacca gaaccattgt gtcgcccagc ggctgtccaa aggtgatgcc
     1081 atcagcatga gcaataatcc caccactcat tccgtaataa atctggctgc tgtcaccatt
     1141 ccgactgtaa ccgacattcg tattaccgta agctccacga taattaagag aactgtaacc
     1201 actggtgcca gacgatgtat tacctccgtg ggtgttaccg acctgaacgc tataattcag
     1261 gttattatcc ggcagcagag tgccataaac ccccgataga ttggtcatgc cgcctttcaa
     1321 atcgtttgac atactgtaac tggcgtttga attacgaaat gccgactgac tgtctgtacg
     1381 catccaatga ctgaagggaa cattaagcgt aaaagcgagt aaatgatccc gatcgttttg
     1441 ccatatatta ttggaatagc tgtaattcag cgaagtcgta atatcaccaa tcggcacatt
     1501 taatccaaat gatatttgct ggtcgctgcg tgacgtgttc cagtaacttt ggcgactggc
     1561 actgaaaaat gtcgtaccgt aatttccaag ctgctgagag atgcttattt gttcctgacc
     1621 acgcttactg tagaacagat taaaataatc aataaattgt gtctgctcat tggtgtctcc
     1681 ggtaggaggc ttgacggtgt aaccactcat tcgactgtag gcactgtcgg ataagttata
     1741 aaaaccttgc gtagaatagc gatatcctgc gacctggata ttggttcctg tctggtagaa
     1801 ggatttgctg tagacggatt taaccgattg cccgctgtga cgggtgccat ctgcaagtgt
     1861 cgtattggcc tgcgtgatat cgaaagaaaa ggcaccaaaa agtcctaaat ctttaccaat
     1921 accaaggttg aaggcctgat aatcttctgc aatttgcatt ccgccataag gtgtccagtt
     1981 tccttccagt ccatgcatca agctaccttg tatgaacttg ggggagcttt gcaggttatt
     2041 tccactacga tattccccca tggcaagcgc ataacgcgta tatccagcac gttggagaac
     2101 cggaacagac gaataaggaa catataatgt ctgaatactg ccgtctgcct cttttatggt
     2161 tacttgcaga tcaccaccat tggcggcaga gttgatatca tcaatagtaa aagggccggg
     2221 tggaacagta gtctgataaa catcgtatcc gttctgtttt acactcactt gtgcggtgcc
     2281 aagggcaata ccatgaatca ccggagcgaa accatgttgg ctatcgggca acatcgcttc
     2341 tgttgaattt attttgaggc cacgaaagtt cacactatca aaaatatcgc catcggtata
     2401 actatcacct accgttaacc gtgagcgtaa gggaataatg tcacgttcag ccgacgtatt
     2461 gatatgctgc catttattgc tgttagatga attgctactc ccactgttat aactccacgt
     2521 tgagttatcg cgcagtcgcc aactaccaat gttgatgcca ctctgtaaat tcaaatatgc
     2581 atagttggat tttcctgcat tatggttact acgattatta atggaattac cattaaaact
     2641 ataatttaga agcccagcat ttattccttc ttcccacagt tcaggagaaa catagccgcg
     2701 agccattctg ccaacataaa tttgcggaac ggagagtgac aaatgttgct gaccaacatc
     2761 aaactcagtt gatgcgtcgg ccaaacgatc ctgaagtggt gtgcatgcgc tgttgtccgg
     2821 cacatgtttt tctgcagaat gttccttatt gtctaataac gcagattttt ttatgccaag
     2881 actgacaaga aggtctgtac tcagacatgg gatgagatct gcgttattat catctgcaat
     2941 aaaagtaata tcccgactag tcataaattc gtcgttcaaa taaatgtcga cccgatatgt
     3001 accaggtggt gcctcgcgtc ccttagtaaa ggcggataaa tcgacagatt cagcaagatc
     3061 attgcttaaa aaccgtggat taaaataata ctctgcatca acgggaaaaa ccgcagttgc
     3121 taagccaagg gcaatggtaa gccgtgcaaa gcgtggtagt attaacacct gatgcatacg
     3181 atatgcctta aatgcggcac gaaaggctgt cattattaat tccgattgag tttattatta
     3241 attaagtcac tggcttactg catggttgcc ttaatacgcg gagttaatgc accgtaatca
     3301 ttgatcgtct gaaaactgat atccccggtt gcagcatgcg ggatatccac cgatacttca
     3361 ccttttggcg gcaccatggt gtttgggaga ttgctatttc ctgctttcat atttgttacg
     3421 gtaatgaagt agggcgttgg attaataaga gtgagtttgc taccgctgcg acgaaaccga
     3481 agcattgctg gcgcttcttc aggtgccatt gccaggttcg tggggcgata aaacattttt
     3541 atgcggctaa taattgccag ctgtaatgta ttctcattct tctggtcttt ttccatagca
     3601 ggaatagctt taacattcac ccagaacagg ctttcacggt cgcctggtaa ctgatgatta
     3661 gtagcgttga ttatccgcag cgtattctct tttttacctt gcatggaaaa aagcggtggg
     3721 gtaatgacaa actgggtgtc tttttggtca cctgcatttt ctatccatga ctgaatgaga
     3781 tagacactgg caggatcatt attcgtgaca ggcaataaaa cctgtttctg gtttgccgga
     3841 taaattaccc gcgtcgcacc cagtgcgaca gctgcgttgg caacggtgct atggcaagca
     3901 aagagcaata aaagtaacac tgtcgccata aaggaaatag agtagggggt acgcgtagtt
     3961 tgcatctgat gcattctcca tgtgttaaga ggataagcgg gaaaaccgtt acatcagaca
     4021 atcgattaat gttgctaata cattggcgag tcgccgggtt tccagactta atgcgtttgt
     4081 aataaatgtt ggttctcttt taataggaaa accttgctac aaagtaaatt aacagtggtc
     4141 gttactgatt catcaccctc ggctgcgctt accgcagcag acgacatcgc caacacagaa
     4201 acgacaatca taccaacatg tttgagtttc ataattctcc aaaatttata tttaagtagc
     4261 tgaataaaga gggttaacaa ttaagtcatt ctgttattgc ttaaaaacaa gaatcattct
     4321 tgattggttg ttgccctgag aatatagttt ccagggttat tacatttcac gaagaacgat
     4381 aatatcttta aatcacaagg acacctaatc acaacaagtt tattgtgcac ttgttgaaga
     4441 gagtatttgc aaaaacattt tatgtcgcta aataacatga cgatttcatt atgcatgtta
     4501 tttataaacc gtgactaaac agaatattat tgcgaacaag ggaagtgtca ggaaaggtca
     4561 agggctacca atggttaata tggctataaa tcattagcta tggttaatgt ttgcttgctg
     4621 aaactaacac cgaattgctc taaacagata agtgcagggt ttattaaagc tgaccgacag
     4681 actttcttaa cctggtaata tctctcttgg gtgactctcc aaacatccgc gaatattccc
     4741 gactgaaatg ggatagcttt cgtaaccgac agcataggct gctgtggtga catcgtaatg
     4801 ttcattcagc atcggtcgcc tgacttcatt gagacgtagc catttctgat accggagtgg
     4861 actcattccc gcttgatccg tccttaaata agtaacagca ccctctggtg ttttcgtatg
     4921 cagtgtctat gcgacagaca ctgcgctctt agcatggggc agggaataac caggctattt
     4981 ctccatgcac aggccaatta tgaaagagga gaggcttaag ttcttgaacc ctgaacgaat
     5041 aacgactacc agaaaagcac ttcgcatcac tcagacatga tttaacataa tatacattat
     5101 gcgcaccagt ataaaccaag gaagaatcca gtcgttggcg gtcatgattg tcgtgctcat
     5161 taacaacgac caaaccccat atctcactta ctaccgtatt ctcggcttaa ccgtccatgc
     5221 aacctcaaca cattggtttc aactgccgtc accacgttct ccggaaaatc tgtcggtaat
     5281 gaagtcttca cgttatccag tgctgccgga atcattctgg caaagtcact taggatttca
     5341 tgcatctgca cttccgggaa tctcagcacc tttgctgtcg ccaaaaaatg tcgcggataa
     5401 attttatcga ttgccgtttt tttgcctttg gatgcgttaa gccccattgc cagtttgaga
     5461 tcgctgatgt gtattcccgt accgccaagg accggaaatg ctgaaatgat gtcgtaaaat
     5521 ggcgtgagtc gataactgcc gccagcctga ataaatacgg agaagttttt tgcatggcca
     5581 tccgttgcgc caatcaacca ctggaagacc tggaatttca taaaatcata acgatcgcga
     5641 agcgcctcgc tggaccccat caaaaacgcc atgatccgcg cgatgcctgg gcctccatct
     5701 gattcatatt tcacagatga aggtaaaccg aatgtctgac acatatcctc ctgtggcaag
     5761 cgaagtaaaa ccgttcgctc agtattccaa cgcctgtcaa aacgttcgac cgctaacgcg
     5821 cgcacccttc ccgctttaat gatttctgcg tccggaacat tcaacccaag ttctttcgcc
     5881 agcagcagac agtaatactc attatcaacg ctttggctga gatcgagcgt cgcattgggc
     5941 tgcctgattt cgccaatcgg taatttaatg atgtgcgtcg tcggcgttat tcctttcgga
     6001 atgcaccagt cattgcctat tctaagcagc gctgtcttct cctgcgcgcc agcaaccgag
     6061 atgcgaaagt cattttcttc tctaatcatg cccagaggga tatctgcttt ataagccgtt
     6121 aatacttctt caagcctggc ttcagtaagc ttttcccatg ccattatcgg gcgcgttatg
     6181 gtttcatttt cgggtaataa cgttacggca ccaacgctgt ctcgccctat ttctgacaat
     6241 aaatcaaacg gttgtctgga tttagcatga taacgtttaa cgatccggtc acgtacaatc
     6301 gggctatcgg gtaacaggtt atcgaagaag ttaaatacgg catctgaggt gatattcccc
     6361 ctctgcaatg gcagcgaaag tgacaacggt ctggcataac ggctggctaa ccactccggt
     6421 gcatacttaa aggtgtgcgc gccgttggct aacttcgtta actcgcctac ccgctggttg
     6481 ttcatccaag tgacaagttt aggcattacc actccagatc ttgctgttct gttgattctg
     6541 gcgaggcatt tttcgtgtcg catagtgtca ttgagagttc aagcgactgt aaaatcttaa
     6601 aaaatgtcgt gagcgtggta ttgtcagggt tgttttcgaa attggaaatt gtcgcctgct
     6661 taatgccaat ttttttcgcc agctcgctct gcgtccagcc attttgctgg cgaaccagtt
     6721 tcattgcatt cgccaattgc gttgggctat agatcttctg aaagctcatc atgtcatacg
     6781 tccacagcaa atttatccgc ttaaggggat attatcagtt ttatccttta gtgaggataa
     6841 agtcaatctg gaaacacatc ttatccgctg tacgggataa acgctgcgat atccgcgatc
     6901 gcggataaaa gggaggcttt aaagcctttg aagtcggcaa tattaagccg catgccatct
     6961 cgacatgcgg cttatacggt ttaccagcta tatttcactc ccagcatgcc ctgagtatcg
     7021 ctatagcctt tatcacctag ttgcacaccg acattccccc acaggctaag gttgttattt
     7081 actttcgcct caaccccggt acgtacttca ccgagattac gcgcaccttc acggcctacg
     7141 gtttgaccat tcatcttcac ggcgtagact ttgctgttgt tgatccaatt cgcttcaatg
     7201 taaggctgga actcacgctg tttaccatcg tcacgctggt gatggctgtt caggtaggtt
     7261 ttcaccccaa gtcgcgtttg cacatttccg tcgccttccg tttcaatgcg cgttccgtct
     7321 ttccgggtat ggtcggaatc tttcacaccc atccaggtga tttgcgcctg tggctggacg
     7381 taccaggtat tcagcgtctc ttcgctgccg ctaaatgttc ccgcttcaaa ggtataccca
     7441 ccctcaacag aggccgtcac accgcgagaa tcatagtcgt cagcagaacg gttatcggaa
     7501 ctgacgctgt tatcaaacca gttatacagc gcccagctgt caacataagc gccggtctta
     7561 ttcgcatcgt tctgatacca ggtcgcgtac agcccagcgc tgtaaccgct gatgcgccca
     7621 tccgatttat aacccacacg attactctga gtattactgt gctgattagc gtaacctgcc
     7681 atcacgccaa gatgccagcg atcctgcgcg ttgctactcc actgcgccaa atcgccgcct
     7741 agctgcaata catagcggtt agcctgagta tttagctgac cgtcaccggc ccttgaacgt
     7801 tcgtgccctc cgacatgacg catccacata ctgcttgccg acccctgaga atgcagtgaa
     7861 tctatatact gcggctcacc cagacggtcg tgtaaacgat ggctaaacag cgagttggct
     7921 gcggcaatgt tgctgatata gcttccggcc tccgggcgat aaactgatgg gccttccgga
     7981 tccacaacag ggggattatt gatggggtcg ggcgtatccg gtggcgttac gccgtcccat
     8041 ttactggtca gataccagtt tttctcgtca ttccccttcc ctttagccag cgtgtagacg
     8101 taagccccag cttcgacagt tccggtggtc agcgcgaagt tacctgcaga attaccgcca
     8161 acctcaatga gttcaatacc gttgaccgtt tgtgcaccga cgccgccaat gttatcaacc
     8221 cgaacgcgag tgttcccttg ggtatcgcct ttcacgttca ttttatcggt gggcgaatta
     8281 tcgccgccca gcgtcgcgtt gaacgtcatc aggccattgt ttccggtata gttgccgtta
     8341 acggtcagta cattccccgg tttcccccct tcgctattca tttgaaccgt gccgccattc
     8401 tccaggttgc cgccgattgt ggttttagcg acacgcagtg tccccccagg cataacgttc
     8461 acatcacctg cagtggtgac atttcccgac atcacaccgc tgttatggat attaatgtgt
     8521 tgacttgcca tattaatggc agagtcggaa ccgaaagcaa tttccccccc cacgatatcc
     8581 gtcgtaccct gatacgccgc ggaatcgttg ttaagagtca ggatcccggt acccagtttt
     8641 gtcacatcac cgctaccgct gatactgtgc gtcatcgccc agctacgctc agtggagatg
     8701 gtgagcaggc cattattgat aacggaagca tcacccaggt ttttctgctc gttgacgctg
     8761 agcgcgctgc ctgtatcaat gttgaattgc cccacaaagc ggctattatc gccatccagc
     8821 tctacatctg tcctggcggt tgcgctcacg atacccttcc cgcttatgct attacgcagt
     8881 tcgccagtca cgttttttag cgttaacaga ccgtcattgg caatatttcc tctgcctaac
     8941 ccctgagtat tatcgaggct gacttccgca tttgggctaa tgctggttaa cgcattgtag
     9001 cgtgcattaa gcccctcgat agccagcgtt ccccctgtaa cattcaggtt tccgccacct
     9061 gtcagttcac cctgactgat cccaccttta tttaccgtca gcgccccctc tttgaacaaa
     9121 acagtcgaac ccatctgccc ggtgaatgtc tctaccgtct gcgtcgatcc attaagatcg
     9181 acgatggccg cgttgctgat gttcagttcc cgggtgttgc caagtgcacc atccgcatcg
     9241 gtacgtaatg tccccatctg aacgtaggtt gccccctgat agtcgttctg accgttggaa
     9301 agcgaaacct gtcgcaccgt attgattgcc agatcccctt caccaccgat ttttgccgac
     9361 atatcggccg ttgcgccata ggctccgcca tgttcggcta acgtcagctt ttgcccacca
     9421 tggatgttca gcgctttcag cccatagtta acgtacaaac catcacctgg tgcggtcgtg
     9481 aggcggaatc cataatcacc ctcggcgacc accgttccgt tttgcgcaat gtgtaacgtt
     9541 ttgtccgctt ccacctcgtc gccctgtaaa tcacgtaacg ttaatgagcc acccgaccca
     9601 ataaccgttt gcgccttcac cagttgaacg ccgacatggc tatcgtcgtg ttccagcaaa
     9661 ttgagcgtcg tcagagggtt attcgccatg ggatcattcc acggtttagg cacgtcgata
     9721 agcacgtcgc ccgtcccgtt tacctgatag ttacggcctt tccaggtgta gtcacccgcg
     9781 ccgacaacca gcgtatcgac gctgatatat ccctctgcaa gcgtcgcagc aggaatatcc
     9841 gtatcgaaaa tgagcgtacc gccattcatg gccagtccac caatggattg ctctcccact
     9901 tttaccgatg tggtattttc actgtcagac tgcaacatcg cgtgagtaag cgcagcggtg
     9961 ttgtcgcgtt ccagagtgaa ggtactgtct ttcagttggg caacaccggc gaattcagtc
    10021 cctgttgcat gggtaaagcc aaacatcttg tcgtaggatg acagctgcac tcgcatcaag
    10081 ccatcgcctt tgagcgcatt ggtcagcgtg taatctcctg cactgttcgt tgatgcgaga
    10141 atgtcgagcg taccggggct tgcaatggtg acttcactcg aacccatgcc cgttacccca
    10201 tctgccgtat gagacgcaat ggtcaggagg ccgtcattga ccagcgtttt accgctataa
    10261 gtattccctg cattgaacac cgtatggcct gcatcatgga tcacttttcc gtctttatcg
    10321 tcacctgtaa tcagcatatc gacctggtag ccggcatcac tgttattagt atgattaaag
    10381 acaaaaacac cttcgccaga accaaactct actttcgtcg cgttggttat atacccggca
    10441 tctgccgccg cctcaccgtg agctgcacca atgtttagcg ttcctacagc aggttcaaaa
    10501 acacctaagt aaacttctcc accttcgaca ttcagcgtgc cgctattcgt cagggttaac
    10561 gtacccgtac cagatgtccc tacgtacata ttgaatgttt caagaagaga gttctgccca
    10621 tccaccctca cgtcgccctt acttttgtca ttgagagcta tctgtgtatc acgcgcttta
    10681 actatacctc cggtggtaat attcagttca cccttgccta atacaccgac ctgtagcaat
    10741 tgtgcgttag tagatgatgt ctttaaattc cagagactgt ccgttgaaat attaactatc
    10801 cccttaccgg aggcatttcc tccgataaat ccatagcccg ttgaattaag ggtggcacca
    10861 ttactgacat ttacgatacc gctaccaaaa ttaccgacat tgatacccac agtatcgaac
    10921 gatgatgtcg catccatcag gttcagtgtg ccgataccgc ttgctttatc gcccaaaaaa
    10981 gtaatatttt gcgatacgaa cttaccgcca tcgctaatat tgaggtttcc gacgcccgca
    11041 acaccaatgg tggtatagac attcttattg acctcccaca tcccccccgt ggtgatgctg
    11101 acattcccga cgccggtttc tccataaccg agtgagcttc ctccgttgct gacaacaagc
    11161 ccttcattac tgatattcat ttcgccgtgg ccgtcataac caagattagt tccgagatta
    11221 gtgataacgg agttcttatc cttaacagta atgttgcctg tgcctgtttc tttcatcccc
    11281 gcagtgataa ttcccgaatc tactttacct tcacgcgaga cattaagttc accgtcgcca
    11341 gcatcaccga tatagatata gcggaaagct tcgcccgttc cgaggaaatt ccaatgccct
    11401 ttatcggtca cgttgacgac accgtgggaa ccgtcctgaa cgcccactaa tgaatattct
    11461 ttgttattaa ttagtccatt attggaaata ttgagtgtgc cattaccgaa atatccatta
    11521 tagagtctgc gtaccgtgat gacagagtct tgatcctgca cattcagggt tccgacaccg
    11581 gtggcattgc caccgataat cgtattttca gccgtaatca gtccaccctc gcgaatagtc
    11641 gcctccccag ttccttgatt accaatttga aattcaattg aggaatcgtt attttttatt
    11701 agccactcgc cacccttttc aacgacaacc tggccattac tgcccgcctg atagcctaaa
    11761 atggcgacga ttgaactcgt gacgtaaccc ttatccgtaa tatttaatga gcccgtaccg
    11821 taactcccta tttcgaataa ttcggtcgtc agaacagagt cctctccctc aacattgacc
    11881 gtcccgacgc ctcctgtcga agaacctaat cttaaatagc ctccatcgac gtgacccttc
    11941 tgtttaatat tcagcgtccc cgttccggat tgacccacat ttaaaggcct tgcattattt
    12001 ccgctatcat acaatcgcca ggtgccaccc aaaacattaa cggtgccctc tgagtcctca
    12061 ttagcgccaa tgacgctggt agtaatagtg gttaaggagg cattaccgcc agccaaaata
    12121 ttaagcactc cagtgccata ccagccaacc aggtaggcat cataagcaac atcagtatca
    12181 atattggtaa tctgatcatt atcaacttcc agacttgcac cagacgctga accgcttagt
    12241 gccagcaaaa cacccagcgt caatctactg aatttcgttg tcagtccaga ggatttacgc
    12301 aaattaaccg tcgatgtttt acctgccctg cgagttaatt ccgagcaggc ctgaaatacc
    12361 tgtagagtgc aattccatat cacgcgatag attctattca tataaacgct ccatatacaa
    12421 acaatacagc cacgaaagag atgagtcgtc agacattaaa aatgaaactt attaaattgt
    12481 cagaggtctg tattaagtgt tagttggagg tgggaaggtg tcaatttggc taatttgcta
    12541 atactttcga attgatagat taaaaaatgc atagttctta ttttatttaa aaatgaacta
    12601 tgagttattg ttgattaata agaaaactgt ttctttcaat aggaaaatta tcatcatcat
    12661 atttaacaaa gaatagcact aattgctaaa aatcgaagtt tattaaaccc cttttgcatc
    12721 cattaatgtc tttaggaata ttcgctataa aataagggtt atgcttaatg ctttaagaaa
    12781 aatagcaatt ttcccttgaa tatagtactg gtgatggaac gatgaatctg caagctggca
    12841 tttaacaagc cagctctaaa agaagggaaa taagaaaaac tatactcaaa aactaacagc
    12901 cacggtcatc atgatgtggc tgtcaatgaa actataaccc aggcgctttc cataacgacg
    12961 tcgtcagtcc atgatcaacc agccccagct gatcctgata aactgcctgc cacttatcgc
    13021 gtgaatcctg ataaagttca tgcttttccg ggtctggtgt gtgcgtccgt tcccagcgaa
    13081 ccaggcgttc tccggtttct gccattgatg aaaaaattcc ggcaccgacg ccagctgcaa
    13141 tggcacatcc taatgcggtg gcttctttga ctaccggaat attgacgggt aatcccgaga
    13201 catcagcgag aatttgactc cataatttcc cttttgaacc tccgccagca aaaaccagcg
    13261 aggtgggatg aatattcgag aaatcagcaa tttgctgcaa gttacacgct gatacaatcg
    13321 ccgcattttc ttccagcgca cggaacaatg tcgctttgtt acatttatcc gggtcaatgg
    13381 acaagttaat aaaggaaggc gcagcgtgat accaggtttt aaagcgcatt ctgtcggaga
    13441 agatcggcat tacgccccac gacccaggcg gcacccgact ggccatctct tccagcagcg
    13501 tataggtgtc gatgcctaaa cgttcggcaa tcagtttttc ttcggcacag aaagcatcgc
    13561 ggaaccagcg catggtgagt ccggtaaaaa agcttataga ttcagcttgt accatgccag
    13621 gaataacatg aggattaacg cgcacgttca tttctgggtc tgtcaccggc gcggctaaat
    13681 ttacaacttg ctgccagaat gtgccgccaa gaaccgcggt ttgtgccgga cgcacaacgc
    13741 ctaacccaag gcaaccaagc tgcacgtcgc ctcctccaac gaccaccgga gtgcccgcct
    13801 tcagaccgca gagttccgcc gcttgtgaac ttaccacgcc cagcaatgtg ccggtttctt
    13861 tgacaggaga aagaatatcg gcacgcaggc cagccatatc cagcaatgca ggtttccagt
    13921 cacgggtggt tagatcaaga agtcccgtgg tgccagcgtt agagggatcc accgccagtt
    13981 cgccgctgag catataggcc agccagtcgc tgatcatggt gatggttgat gcctgacggt
    14041 aaatatcgga acgatggtgc gccagccaaa gtaatctggg gatggcactt aaagccagtg
    14101 tttgtccggt cgcgcgataa acttcgtttt caaaggtatt gttgtgcagt tctttaagtt
    14161 cgctaacttc gcgtgccgct ctggcatcca cattggcgca ggcccagatc ggggctcctt
    14221 cattattata taaaacaatg ccttcacgca tcgaacatgc cgaaacggca gcgatatact
    14281 ccggggctat gccggcgttg tgcagcgcct ggcgcataca ctcacacgcc agttgccagt
    14341 ttttgttgag atcaaattcc atagaaccag gaacgtccgg tactgccagg tgccgccact
    14401 ccgcctgtcc cactgctatt tgattgcctt ccaggtcgaa tatcacagcc cgaatacttc
    14461 cggtacctgc atccagcgcc atcaggtaat actttgattc tgaaggggta aagagtcgag
    14521 ccattagatt atcctcggct tatgcgttct gtctgttcct ctatacgttc tccatcattc
    14581 ccggtaataa ggtcatgcaa atttaactac gtaaaatcgc cgctgctgtg tcctgatcgg
    14641 taaccagtgc gttgatataa ccgcctttca ttgcagcggc aattgcttcg gctttatttt
    14701 ctccccctgc cacgccaacc cggacgggta tggtcttcag cgagcttaaa ggtaagccaa
    14761 tcagttcgtt atgtatttta atatccgtga caacgtcacc ttttgcatca aaaaagtagc
    14821 ctaaaatgtc gccaaccgcc ccttttcgac caatcattaa ctgttcgccc tggctgatat
    14881 aaccggagcg aatgatcgtc gcgtcgtcct gttgactgac ggccccaatg ccgacaatcg
    14941 ccacatcggc tgcttgcgcg gctaacagaa catctttgac gcaattttca ttttttagcg
    15001 tacgggcaat gtcagcggag gatgcccgca acggagccgg aataatattc acactgcacg
    15061 ccgcgttaag ctgcccgata cccgtcatat aagaaccgac gccaccggag agcgtgacca
    15121 ggcgaatttg ctgtgacgaa ataaaaccac ttaagcgttg cagcgtattc atggttgcct
    15181 cgccaaaacc aatcgccagc atctgttgtg gttgaagtaa actcatcaac atatgcgccg
    15241 cgcctatccc cagtcgcccg ccgacatcag catccgcaag cccagggatc acccggacat
    15301 gttgcagcga aaactgacga cgtaattgag tttcatattc cagacagcct tcaaagcgag
    15361 aattaatctg tacgcgaata atgccggact gatgcccttt ctccagcaag cgcgacactt
    15421 tcaaacgggt caggccgaga cgatcgctga tctcgctctg ggtcagcccg tcgtgatagt
    15481 aaaaccacgc gatccgcgcg acctgttctt cttcacacat tccctgttct gaaattgccg
    15541 aatcgttgat tgtcataatt cattcttcac tttgaacata tttaaatctt taatgcaatt
    15601 gttcagttct tgcgcattta tatctgtgat ggcagccaca gtttgactct acgagcatga
    15661 acaaacgcaa ccgtgaaaat caaaatagca taaattgtga tctattcgtc ggaaatatgt
    15721 gcaatgtcca cctaaggtta tgaacaaatt aaaagcagaa atacatttgt tcaaaactca
    15781 cctgcaaaac tgaacggggg aaatatgcaa acgagtgata cccgcgcgtt accgctactt
    15841 tgcgcccgct cggtttataa acagtattca ggggtcaatg tcctgaaagg catcgatttt
    15901 acgttgcatc agggggaggt ccacgccctg ctcggcggca atggtgccgg taaatcgacg
    15961 ttaatgaaga ttattgccgg tattacccct gctgatagcg gtacgctgga gattgggggc
    16021 aacaactacg ccagattaac gccagttcat gctcatcagc tgggcattta tctcgttccc
    16081 caggaaccgc tgcttttccc aagcctgtcg ataaaagaaa acatcctgtt tgggatggca
    16141 aaaaaacagc tctccatgca aaaaatgaag aacttgctgg cggcgctggg ctgccagttt
    16201 gatctgcata gtctggcagg atcgctggat gtcgccgatc gccaaatggt ggaaatcctc
    16261 cgcgggctaa tgcgcgactc gcggattctg atcctcgatg aacctaccgc ctcgcttacc
    16321 cctgcggaaa ccgaacgctt gtttactcgc ttgcaagagc tgcttgctac tggcgtgggt
    16381 attgttttta tctcgcataa gctgccggaa attcgccaga ttgccgatcg aattagcgtg
    16441 atgcgcgacg gaaccatcgc cttaagcggc aaaaccagcg aactgtctac cgacgacatt
    16501 attcaggcca tcaccccagc ggtacgggaa aaatcgctct ctgccagcca aaaattatgg
    16561 ctggagttac ctggtaaccg cccacaacat gctgccggaa cgccggtgct gacactggaa
    16621 aacctgaccg gcgaaggttt caggaatgtc agcctgacgc tcaatgccgg agaaattctg
    16681 ggcctggctg ggctggtggg ggccggacgc acagaactgg ccgagacgct ctatggtctg
    16741 cgtactttgc gtggcggacg cattatgctg aatggtaaag agatcaataa attatccact
    16801 ggagaacgtt tactgcgcgg tctggtttat ctgccggaag atcgccagtc atccggactg
    16861 aatctcgatg cttcgctggc ctggaacgtc tgcgccctta ctcataacct tcgtggattc
    16921 tgggcgaaaa ccgcgaaaga taatgccacc ctggaacgtt atcgtcgggc gctgaatatt
    16981 aaatttaacc aaccggaaca agctgcacgg acattatccg gtggcaacca gcaaaaaatc
    17041 ctcattgcca aatgcctgga agcttcgccg caagtattga ttgtcgatga gccgacgcgc
    17101 ggcgtggatg tctcggcccg taatgatatc taccagctgt tgcgcagcat cgccgcacaa
    17161 aatgtggcag tgctgcttat ctcctccgat ctggaagaga tcgaactgat ggcagatcgc
    17221 gtgtatgtga tgcatcaggg cgaaattgcc cactctgcac tgaccgggcg cgatattaat
    17281 gtcgagacta ttatgcgcgt tgccttcggc gatagtcagc gtcaggaggt gtcatgctga
    17341 agtttattca gaacaaccgt gaaatcacgg cactgctggc ggtggtgctg ctgtttgcat
    17401 tacccggttt tctcgaccgc cagtatttaa gtgtgcaaac gctgaccatg gtttatagca
    17461 gcgcgcaaat cctgatcctg ctggcaatgg gcgcgacgct ggtaatgctt acgcgcaata
    17521 ttgatgtttc agtgggttcg attaccggaa tgtgcgcagt gctgttgggg atgttactga
    17581 acgcggggta ttcactacct gttgcttgtg tcgcgacttt actgcttggt ttgctcgcgg
    17641 gatttttcaa cggtgtcctg gtcgcgtggc taaaaatccc tgccattgtt gccacccttg
    17701 gcacgttagg gttgtacaga ggcatcatgt tgctgtggac tggcggtaaa tggattgaag
    17761 ggttacccgc cgaactgaaa cagctctccg caccgctgct gtttggcgtt tccgcgattg
    17821 gttggttgac gataattctg gtggcattta tggcctggct gctggcaaag acggcgtttg
    17881 gacgcagttt ttatgccacg ggcgataatt tacagggcgc tcgtcaactg ggtgttcgta
    17941 cggaagccat tcgcattgtg gcattttcgt tgaacggctg catggcggca ctggcgggaa
    18001 ttgtgtttgc ttcgcagatt ggttttatcc ccaaccagac cggtaccggg ctggagatga
    18061 aagcaattgc agcctgcgtg ctgggcggca ttagtttgct cggcggttcc ggtgcgatca
    18121 tcggtgcggt actcggcgca tggttcctga cgcagatcga tagcgtactg gtgctgttgc
    18181 gcattccggc atggtggaac gattttatcg cgggcctcgt gctgctggcg gtgctggtgt
    18241 ttgatggacg cctgcgttgt gcgctggaac gtaatctacg gcggcaaaaa tatgcccgct
    18301 ttatgacgcc accgccatcc gttaaacccg cttcgtcagg taaaaaacgg gaggccgcat
    18361 aatgcgtatt cgctacggtt gggaactggc tcttgccgca ctgctcgtta ttgagattgt
    18421 cgcatttggt gcaattaacc cgcgaatgtt agatctcaat atgttgctgt tcagcaccag
    18481 tgactttatc tgcattggca ttgtcgccct accgctgacg atggtgattg tcagtggcgg
    18541 gatcgatatt tcgtttggtt cgaccatcgg cctctgcgcc attgcattgg gcgtactgtt
    18601 tcaaagtggt gtgccgatgc cgctggcgat tctcctgacc ttactgctcg gcgcattgtg
    18661 cgggctgatc aacgccggat taattatcta taccaaagtt aacccgctgg tgattacgct
    18721 tggcacgctg tatctgtttg ccggaagcgc cctactgctt tccgggatgg ccggagcgac
    18781 ggggtacgaa ggtattggtg gattcccgat ggcgtttaca gatttcgcta acctggatgt
    18841 gctgggactc cccgttccgc tgattatctt cctgatatgt ctcctcgttt tctggctctg
    18901 gctgcataaa acccatgccg gacgtaatgt gtttttgatt gggcaaagcc cgcgcgtggc
    18961 gctttatagc gcgattccag ttaaccgcac cttatgtgcg ctctatgcca tgacggggct
    19021 ggcgtctgcg gtcgccgctg tgctgctggt gtcgtatttt ggttcagcac gttccgatct
    19081 cggtgcgtcg tttctgatgc ccgccatcac cgccgtggtg cttggcggtg ccaatattta
    19141 tggtggttcc ggttccatta tcggcaccgc cattgcggtt ttattagtgg gatatttgca
    19201 acaaggtttg caaatggcag gagtgccaaa tcaggtgtcc agcgcccttt ccggtgcgct
    19261 acttatcgtc gttgtcgtag gtcgttccgt tagcctgcat cgccagcaaa ttaaagagtg
    19321 gctggcgcgt cgggccaata acccattgcc ataaaggata tcttcatgac acttcatcgc
    19381 tttaagaaaa tcgccttact tagcgctctt ggcattgccg caatctctat gaatgtgcag
    19441 gccgcagagc gtattgcatt tattcccaaa ctggttggcg tgggattttt taccagcggt
    19501 ggcaacggcg cacaacaagc gggtaaagag ctgagcgttg atgtgaccta cgacgggccg
    19561 acagaaccca gtgtttctgg tcaggtacag ttgattaata acttcgtcaa tcaaggttat
    19621 aacgccatta tcgtttctgc ggtttcgcct gatggcttgt gtccggcact gaaacgcgcc
    19681 atgcaacgtg gtgtgagagt gctgacctgg gactctgata ctaaaccgga gtgccgctct
    19741 tactacatta atcagggaac gcccgcccag ttgggaggta tgttggtgga tatggcggcg
    19801 cgtcaggtga ataaagacaa agccaaagtc gcgtttttct actcaagccc caccgttacg
    19861 gaccaaaacc agtgggtgaa agaagcgaaa gcgaaaatcg ccaaagagca tcctggctgg
    19921 gaaattgtca ctacgcagtt tggctataac gatgccacta aatcattaca aaccgcagaa
    19981 ggaatattaa aagcgtatag cgatctcgac gccattatcg cccccgacgc caacgccctg
    20041 cccgctgccg cacaagccgc agaaaacctg aaaaatgaca aagttgcgat tgtcggattc
    20101 agtacgccaa acgtgatgcg tccatatgtg gaacgcggca cggtgaaaga atttggcctg
    20161 tgggatgtgg ttcagcaagg caaaatttca gtgtatgtcg cggatgcatt attgaaaaaa
    20221 ggatcaatga aaacgggcga caagctggat atccagggcg taggtcaggt ggaagtctcg
    20281 ccaaacagcg ttcagggcta tgactacgaa gcggatggta atggcatcgt actgttaccg
    20341 gagcgcgtga tattcaacaa agagaatatc ggcaaatacg atttctgatg tgcattactt
    20401 aaccggagta agttatggca gatttagacg atattaaaga tggtaaagat tttcgtaccg
    20461 atcaaccgca acaaaatatc ccttttatcc tgaaaggttg cggtgcgctg gattggggaa
    20521 tgcagtcacg cttatcgcgg atatttaatc cgaaaacggg taaaaccgtg atgctggcct
    20581 ttgaccatgg ttattttcag gggccgacta ccggacttga acgcattgat ataaatatcg
    20641 ccccgctgtt tgaacatgcc gatgtattaa tgtgtacgcg cggcattttg cgcagcgtag
    20701 ttcccccagc gaccaataag ccggtggtac tgcgggcgtc aggtgcgaac tctattctgg
    20761 cggaattaag taatgaagcc gtggcgttat cgatggatga tgccgtgcgc ctgaacagtt
    20821 gcgcggtggc ggcgcaggtt tatatcggca gtgaatatga acatcagtcg atcaaaaata
    20881 ttattcagct ggttgatgcc ggaatgaaag tgggaatgcc gaccatggcc gtgactggcg
    20941 tgggcaaaga tatggtgcgc gatcagcgtt atttctcgct cgcgactcga atcgccgctg
    21001 aaatgggggc gcaaattatc aaaacctatt atgtcgaaaa aggttttgaa cggattgttg
    21061 ccggatgtcc ggtacccatt gttattgctg gcggtaaaaa attaccggag cgcgaggcgc
    21121 tggaaatgtg ctggcaggct atcgatcagg gcgcttctgg tgtggatatg gggcgtaata
    21181 ttttccagtc tgaccatccg gtggcgatga tgaaagccgt acaggcggtg gttcaccata
    21241 acgaaacggc tgatcgggca tatgaactct atctgagtga aaaacagtaa ctgcggattt
    21301 aaggagaaga attatgcacg tcacactggt tgaaattaac gttcatgaag acaagattga
    21361 cgagtttatc gaagtttttc gccagaacca cctgggctct gtacaggaag aaggcaattt
    21421 gcgcttcgat gtcttacagg acccagaagt gaattcgcgc ttttatatct acgaagccta
    21481 taaagatgaa gacgcagtgg cattccataa aaccacgccc cactacaaaa cctgtgtcgc
    21541 gaaactggaa tctttaatga ccgggccgcg taaaaaacgt ctgttcaatg ggttgatgcc
    21601 gtgaggcgaa ttcatcagtt ttatctacaa ttggggtaac gcgctgacgg gagtaaataa
    21661 atgtctgact ggaacccctc tttatatctg cactttgccg ctgaacgatc gcgtccggcg
    21721 gtggagctgc ttgccagagt accgctggag aatatcgaat acgttgccga tcttggctgt
    21781 ggcccaggta acagcaccgc ccttctaaac caacgttggc ctgctgccag gataacaggc
    21841 atcgactcgt ctccggcgat gattgctgaa gcgcgcagtg ctttgccaga ctgccagttc
    21901 gtggaagcag acatccgcaa ctggcaaccg gaacaggcac tcgatctgat ttttgctaat
    21961 gcctcactgc aatggctgcc cgaccactac gaattgtttc ctcatctggt ttctttactt
    22021 aatccgcagg gcgtgctggc agtacagatg ccagataact ggctggagcc gacccatgtg
    22081 ctcatgcgcg aagttgcctg ggaacaaaac tacccggatc gcgggcgtga gccgttggct
    22141 ggcgttcatg cttactacga tattttgagc gaagccggat gtgaggtcga tatctggcga
    22201 accacctact atcaccagat gccgtcacac caggcgatta tcgattgggt gactgccact
    22261 ggattacgtc cgtggttaca ggatctgacc gagagcgaac agcagctttt tcttaagcgc
    22321 taccatcaga tgctggaaga gcagtatcca ctgcaagaga acggacagat actgctggca
    22381 tttccgcgtc tttttattgt tgcccggcgt atggagtaaa tatcacgtca gctggtaatg
    22441 acgatcggga agaatttttg ctggaatttc ggcttcatcg ttcatctgta acaggtcaat
    22501 ttcaatagcg ttgcagatgg catccagtgg taaatcattg ttttcagtac cgaacggatc
    22561 ttccagttct tccgccagac aatccagcga aataaaagtg taggaaatca gcacagagat
    22621 aaaaggcgtc atgtaatgca ggtccacgac cagcgcgaac ggcagcatga tacaaaacag
    22681 ataaacggta cgatgcaaaa tcagggtgta ggcaaaggga attggcgtat aggcaatgcg
    22741 ctcgcatcct gccaggaccg ctgaaatatc attaagccga tcgttgaggc taataaacag
    22801 gatatctgaa agctgcccat tgcggcgctg aaccgccaac cactccccca ttattaacaa
    22861 gatacggtta gctggagagt tcgaagccag tacaggctga agatcttcag tcttgagata
    22921 atgagccagc acttccgcct gtggctgttt gcgtaatgtc atgcgtaaac agtgggcgaa
    22981 ggcgatttgc aaccgggcaa actcccttac acttgccgaa tccggcaatg tcgtttttac
    23041 ctcgcgcagt aacgaccgtg aggcaatcat caactgcccc caaagttttc gcgcttcaac
    23101 gtaacgggcg tacccggcat tattacgaaa accaagaaaa atggcgatgg cgacaccgag
    23161 aatgctgaac ggtgcgaggg tgaatttgat gcccagatgc gtgtaccagg gcagcatgaa
    23221 aataacagcg atagaaaaga gaaaatggag tagtaagcgc gatgatatct tggataatac
    23281 tgagccgtgc cagacaaaaa tacggcgcag ccagtgttgt tgtggacgaa caatcatggt
    23341 tatcttcagg cgtgaaaaag tcgccctatt aaacgtgatt acgatcacat tctcaagacg
    23401 ctatttacaa attacctaca agcttacaac attaacaggc gctgcatgtg gcatctgtta
    23461 atgataaagg cacataggat gttgtaacta atatagtgaa ataagaaacc cggtcgaaac
    23521 cgggttcaga agtaacggtg ttattagcac aacggacgta cagcttcgcg catccctttt
    23581 tcaagaatcg catccaggtc attagcaacc tgctcgacca gaccaggcac ttgcgtcagg
    23641 tcctgctccc agtggtcttt ttctgccaac acaatcgcta ccagttcctg ggtaccgata
    23701 acacggtcac gatgctggct ccagagttgc tgataacgtt ccagccagtg tgcatcgtcc
    23761 tgtaccggat atgtttctcc gttacgctca ccacgataga acgcaatcaa tgccgctaat
    23821 gcgaaagtaa ggcgcgccgg aagtgtgccg tttgccttct gccctgccag cagctgcggc
    23881 aggatgcggg tgcggaactt ggtcataccg ttaagcgcga tagacagcag ctgatgctta
    23941 atgtacgggt tacggaaacg cccggtgact gcactggcga aagattccag ttcatcacga
    24001 ggcaaatcca gtaccggaat aatttcttcg tagatagctt tttcaacgaa tgcgcaaatt
    24061 tcagcatcgt tcatcgcttc acctacggta tccagccctg cctggaacgc caccggcacc
    24121 agcgcggtgt gcgcaccgtt gaggattgcc actttgcgtt ctttgtacgg tttaatatcg
    24181 tcaacaatca gcacgttgag cggatatttg tccagacgca gttcagtcgc taaggatttc
    24241 ggtccctgaa tcacaaacag gtaaaagtgt tcagcggtgt cgagaaaacc atcgtgataa
    24301 cccagctctt cttccagttt agccacttca tcgcgcggat aaccggtaac gatacggtcc
    24361 accagcgtag aacagaagct gttagcctga tccagccatt gaataaatgc ttctggcagt
    24421 gcccactctt gcgcatagcg cagcaccagt tcacgcaacg cgtcgccatt gtagtcgatc
    24481 aactcacacg ggatgatgat ccaaccttta tccagcgcac cgttgaaatg gctaaaacgt
    24541 tcgaacagca gacgggtcag ttttgccgga taacttaccg ctggcgcgtc atcgaattta
    24601 tcgcccgcat ggtagctgat acccgcttcg gtggtattag agaaaacaaa gcgcatttcc
    24661 gggttgtgag ccagtttcag gaattcatcg tattcactgt agacgctgat ttcacgatta
    24721 accgagcgaa tcagacgcgc gtcgctgacc gcttccccct tctcattcag gccacggata
    24781 atggtggtat acagaccatc ctgcgtgctc agtgacggtg ggaatgaagt ttcaatcgga
    24841 cgaacaacga ccacaccaga attcagatcg gtgtgctcat tcaggagatc gatttgccag
    24901 tcaacaaagg cgcgcaggaa gttaccttca ccaaactgaa tgatacgttc tggatactgt
    24961 gcaccgggaa aatcgcgacg atttagtgtt ttcacaatgg gttcccttct gattagtcat
    25021 acaacctgtt tgaattggta cgacaggtta gcaaacttta atacgccgaa cccctgtttt
    25081 gatcaactcc tgatgattaa tgagcagttt tatgagaaaa gtgtggcgcg gatcatggtt
    25141 taatcgagga aatacgcctt ttcctggatc ataaagtggt agaacacatt gcattcaaat
    25201 cgcgcggaat gaataaagat gtcagacaac ttcctcaccg taacgcatag tgctggtacg
    25261 gttgcgccca tctttcttcg agcgatacag acacgtatcg gcttcgacca tcaatttatt
    25321 aaaatcatcg gtcagcgttc ggtacgatgc gcgaccacta ccgacgccaa tacttaccgt
    25381 gagataaagc gttttttgtt gccaggtgaa tggttgcagt tcaacgcctt tacggatttt
    25441 ttccgccatt agcagaccat cgacaggatt caccgacggc actgcaacag caaattcttc
    25501 gccgcccatg cgcgccacca gccccttatc accgacaatc ttctgaatat gccgggcaaa
    25561 cacgcttaac actttatcgc cacattcatg tccatagtta tcgttaatgc ttttgaaata
    25621 gtcaatatca agcagcatga ccgtcagatg ttgtgtctgt ttcagcgatg gacttttcag
    25681 cgcctcataa agaccggacc gtgagtaaac ctgagtcaga aaatcaaagt cggctcgcag
    25741 cgcaacttgc ttcattagcg aattgatcgc tgccacgcta aaagaaacca taattgggca
    25801 tatcgccatc gtggcaatac cgagacgtgc ggagaacatt tccggaatgg agaacggcga
    25861 accgaccgag atatcaatca ccgaatttgc caccagtacg atttccaccg caccggtgac
    25921 aaaggtcaac agacatgtta cctgcggcgt atagcgcact gcacaccaga ttaatgcagg
    25981 cagcgggaac gccagactcc ccgctccgcc aatgactacc gaggcaataa ccgacacaat
    26041 aagcgcgatg gcgggcatca tctgttctgc tttaaagcgc ggcagcactc caggaatagc
    26101 caacgtcagc atacaaggca cgatcaacac gcccgttgag aattgctcac tgaaccagtc
    26161 cgcaagcaaa ggccagaaat ccagactatc aatactgacc gaaccaatcg ccccgacaat
    26221 agcgcataat aatgcggcaa tcagacagta attaaatagc cgtaaggcac ttactggctc
    26281 atacttattt ttccccagac gcttatcccg cacgaccagt aaggcgacgg taacaataaa
    26341 catcatattg gagaaattga taaccagtga aaccagtccc cattcggtgg ttatggcatc
    26401 ataaaccagc atcgccacat aactgatcgc atagtaatgc agtcgattaa gccagacata
    26461 gcgggcaaac acccccgcca ttacgccatt cagcggccag aaaagagaaa gttcgtgaac
    26521 cagccgtaac tctgcaccaa taaaatagaa cagcgtggtt agcgcaaaaa tagcgatgct
    26581 attacgtagc agatgacctt cctggaacaa acggaaagtt gaaatggggt gtacatgcat
    26641 taattatctg tccatacaat tgcgggtggc aattatctca acgtaataag taaattcaca
    26701 taaaggatag catgttcgct aacagcggcg gcaaataaag gtaccctggg aatgctattt
    26761 tatcgttttc cgcaattctc atggctgatt catctgtaca accagccagt gatagattac
    26821 cgccacgata taacgttgtt gttcttcgct taacgaaaca ccctgcggaa tgttatgcca
    26881 cttagccaga caaccgcgac agcaggtcgc ggtggcgtgc tgagcgataa acaccggatg
    26941 cccgcgcatg ggggtttgct taccgtcatt agccggtaat gccggagcaa gacgtttagc
    27001 gacaaaatcc gccgcatgtt gttcgatgac tggcgcgcct ttctccaggc aatactgacg
    27061 ctctttcatg cccagacgaa agcgagagcg aaattttgaa cgggataaac gcgcgaagag
    27121 tggatcgaga gactgcatta ataaaccgaa cgccctaact gtttcgtcaa ttgttcaagg
    27181 acggcgatac ccgcaagcga gttacctgca tcatccagtt ccggactcca gactgcgatg
    27241 gccatttcat gcggaacaat cgccacaata ccgccaccaa cgccagattt cgccggtagt
    27301 cccacccgcc aggcaaactc ccccgcgttc tggtacatac cactggtcgc catcagcgcg
    27361 ttaatttgcc gcgcctgcat tggcgtcacc acaggttcat caatatgaat agctttcccc
    27421 tgattagcca gaaagacaaa cgtccgggcc agctctacac agctcatttt cagagcgcag
    27481 taatgaaagt agttttgcag aacggttgtc acgtcatgat ggaaattgcc aaacgacttc
    27541 atcagccagg cgatagccgc atttcgcgcg gaatgttcaa attcggaacg cgctaccacc
    27601 gtatcgtatg aaatatcaga cacaccgctt aagccgcgca cgacttccag catacgttgc
    27661 cgtggtgcgc ttagtcgccc ttgcaacata tcgcagacca ccagcgcacc ggcattaatg
    27721 aacggattac gcggaatacc ctgttccatt tccagttgca ctaaagaatt gaacggtgat
    27781 ccagacggat ctttgccgac gcgttgccag atttcctctt cggagtaatg acgcatggcg
    27841 acaacgagac tcagcacttt ggaaatagac tgaatggaaa aacgttcttg cgcgtctccg
    27901 gcctgaaaaa gctgtccgtc aacggtacag atagcaatcc ccaatcggga accgtctact
    27961 gtagccagcg ccggaatata atccgcgact ttaccctgac caatgagcgg ccgcacttgc
    28021 cgcaagatgt tttctaaaat tgcattatcc atggcgactg ccactttcta ctcctggacc
    28081 gcaggtctga aaagacctgc gagtatatca gagctgaata tgtcgcgtca gatccggtct
    28141 ttccacaccg tctggatatt acagaattcg tgtaagccga aatgggaaag ctcacgacca
    28201 aagccactct ttttcacgcc accaaaggcc actcgcgcgt cgctggcaca ataaccattg
    28261 ataaacaccc caccgcattc cagacgtgcc gccatctgtc tggcctgtgt ttcgtcggtg
    28321 gtaaaaatgg tcgctgaaag gccgaactca ctatcattag ccagttccag cgcatgttct
    28381 gcatctttcg caacggtgat tgccgcaaca gggccaaaca tttcttcccg aaacgcggtc
    28441 atttctgggg taacattcgc cagaaccgtt ggcggatagt agttacctgc cccagccatc
    28501 ttttccccgc ccagtaacaa acgcgcaccc tgcgccaggg ttttctccac ctgatgatgc
    28561 agctcatcac gtaaatcaaa acgagccatt ggtccgagag cgttctcttc atcacgggga
    28621 tcgcccattt tcaaggctgc cgcagctgcc acaaaacgtt cggtaaatgc agaagcaatt
    28681 ccctcttcga taataaagcg ttttgccgct gcacaaacct gtccggtatt ctgataacgt
    28741 ccggctaccg ccgctttaac cgccagttcc agatcggcat cgttaagcac aataaatgga
    28801 tccgaaccgc ccagttccag tacgcatttt ttcagtgccg ctccagcctg tgcgccaata
    28861 gccgctcccg cacgaacact tccggtcacc gtgacagcag caatgcgcga atctttaatc
    28921 atttgactga caccgtcgtt gtcggcattc agccagccat atacgccttg cgggattccc
    28981 gcatctttaa acacctgggc aatgagctga gcacagccca tcacattcgg cgcatgttta
    29041 agtaagtagc cgttacctgc aagaatgatg ggaaccgcgc cacgcatcac ctgccataac
    29101 ggaaagttcc acggcataat cgccagaatc gtccccaacg gtcgatactc aataactgcc
    29161 tgctgatttt ccaccagcgt aggttccgcc ttcagcattg ccggaccatg ttctgcatac
    29221 cagtcacaca aattcgccga tttcgccact tcagcgcgcg cctgattgat tggtttgccc
    29281 atttcacggg tgatcatttg cgccatttct tcgctacggg cgcgcagagc cttaccgata
    29341 ccacgcagtt tttcagcacg ataatctata tttgtctcgc gccagtcgcg aaagcctgct
    29401 gccgccagct gaagtgcgtt ttcgatatcg ttagcgccag cccacggcag cacagaaagt
    29461 tgttcacccg tggcaggatt tattgaaatt gcatgagttg ccggagtaat ggtcatcggg
    29521 gtatctcctt tatgagtcat ggtatgaaga tacgcagatt tactcttgct ttaaaatgaa
    29581 taatattaag ccacttattc acgaatcgag aatattatgg atctgacaca actggagatg
    29641 ttcaacgcgg ttgccgaagc tggcagcata acccaggcag cagcaatagt gcatcgcgtg
    29701 ccgtcgaatc tcactacccg tctacgccag ctggaaacag aactgggggt agatctgttt
    29761 attcgcgaga atcagcgttt acgtctctct cctgccgggc ataacttttt acgctatagc
    29821 caacaaattc tcgcgttagt ggatgaagcg cggagcgttg tcgctggcga tgagccgcaa
    29881 ggtttatttt ctcttggttc gctggaaagc accgcagcag tgcgcattcc ggccacgctg
    29941 gcggaattca accatcgtta tcccaaaatt cagttttcac tttccaccgg cccttccggc
    30001 actatgctgg aaggagtgct ggagggaaaa ctgaatgcgg catttattga tgggcccatt
    30061 aaccatactg ccattgacgg gataccggta taccgcgagg agctgatgat cgtcacgcca
    30121 caaggtcatg cgccagtaat ccgcgccagt caggttaacg gcagtaacat ttatgccttc
    30181 cgcgccaatt gttcgtatcg tcgccacttc gagagctggt ttcatgctga cggtgccgct
    30241 ccgggaacta ttcacgagat ggagtcgtat cacgggatgt tggcctgtgt ggtcgcagga
    30301 gcaggcattg cgcttattcc acgctctatg ctggaaagta tgccggggca tcaccaggtt
    30361 gaagcgtggc cgttagctga gcaatggcgt tggttaacaa cctggctggt ctggcgtcgc
    30421 ggtgcgaaaa cgcgtccgct tgaggcattt attcaactac tggatgtgtc tgactcggca
    30481 aaacagagtt accaatgagc tattttgata gttcttgcgg ctaatatgct ctatatagtg
    30541 atgttccgat gacttatgac tatatggggc aaatatggtt acgccagtaa gcatcagcaa
    30601 ttacatatct cttcctgatg attttcccgt tcgtaatatt gcaccacagg taaaagaagt
    30661 tttaaaggac tttattgatg cgctaagtac aataatatgt gatgaagagt ggcgcacgtc
    30721 tttaaacatc aactcagcca caaaaaagat atttaataac cttgataact tatcatatat
    30781 tcagagaact tcttttcggg gtaacgacac gctatacaat gaaaaggttc agtttaaact
    30841 cacttatccc gtcaagaatg gaagacacaa agaaaatatt gaatttcagg tagtaataaa
    30901 tttaagccct atttatttag ataattttcg ccatgatgga gaaattaata tttttgcgct
    30961 cccaacccaa agcctgtcac tatggggcgc gtatttcaga ccggcgtcga gcgtgtgcta
    31021 tttctgtttc tgaatgattt tattgaacaa tttccaatgt tcaaccttgg cgttcccatc
    31081 aaaagagcgc atacaccaca tattgaaccc ctgcctccgg atcgccatac cgctgcagat
    31141 tacttacgcc agtttgattt gcttgtcctg aattttatct ctcgcggtaa ttttgtcata
    31201 ctcccccgat tatggaataa ctctgaggtt cacagatggt tcgtcaataa agatcctaac
    31261 ttgatcaccg ccattctcga cataacggac agcgaattaa aagaggattt attgcaaagc
    31321 ctgatggatt cattaggttc taacaaacat gtactacccg aagtctgcat ctgcttttta
    31381 tcccttttag cagaacaaga atctcctcat tttcaggact tgtttttatt tttcgccaat
    31441 atgttattgc actatcacca atttatgaat cccaatgaaa gtgatttgaa tgacgtgttg
    31501 atgccagcat cattaagtga tgataaaatt atcaaacata tggcgcgcag gaccctcaaa
    31561 ctgtttgtaa aaaatgaaac gccgccaaaa gttactcacg aagacctggt gaaaaacagg
    31621 cctcgctccc ctgtcagacc acctataccc gcaaccgcca aaacgccaga cctccctgaa
    31681 cgtcattaaa ccgtgatgtt accgactctc tgacgcggaa cagaatcagc gtcagagaaa
    31741 cggaaaacgc gatccagatc acaaatgcat tgtattcaca tcattaaccg ttttaagatc
    31801 atttcatcac tttttcgcaa ctcacccgat aatctgttat gacaacaaac actgtttccc
    31861 gcaaagtggc gtggctacgg gtcgttacgc tggcagtcgc cgccttcatc ttcaacacca
    31921 ccgaatttgt ccctgttggc ctgctctctg acattgcgca aagttttcac atgcaaaccg
    31981 ctcaggtcgg cattatgttg accatttatg catgggtagt ggcgctaatg tcattgcctt
    32041 ttatgttaat gaccagccag gttgaacggc gcaaattact gatctgcctg tttgtggtgt
    32101 ttattgccag ccacgtactg tcgtttttat cgtggagctt taccgttctg gtgatcagtc
    32161 gcattggtgt ggcttttgca catgcgattt tctggtcgat tacggcgtct ctggcgatcc
    32221 gtatggctcc ggccgggaag cgggcacagg ccttgagttt aattgccacc ggtacagcac
    32281 tggcgatggt cttaggttta cctctcgggc gcattgtggg ccagtatttc ggttggcgaa
    32341 tgaccttctt cgcgattggt attggggcgc ttatcaccct tttgtgcctg attaagttac
    32401 ttcccttact gcccagtgag cattccggtt cattgaaaag cctcccgcta ttgttccgcc
    32461 gcccggcatt gatgagcatt tatttgttaa ctgtggtggt tgtcaccgcc cattacacgg
    32521 catacagcta tatcgagcct tttgtgcaaa acattgcggg attcagcgcc aactttgcca
    32581 cggcattact gttattactc ggtggttcgg gcattattgg cagcgtgatt ttcggtaaac
    32641 tgggtaatca gtatgcgtct gcgttggtga gtacggcgat tgcgctgttg ctggtgtgcc
    32701 tggcattgct gttacctgcg gcgaacagtg aaatacacct cggggtgctg agtattttct
    32761 gggggatcgc gatgatgatc atcgggcttg gtatgcaggt taaagtgctg gcgctggcac
    32821 cagatgctac cgacgtcgcg atggcgctat tctccggcat atttaatatt ggaatcgggg
    32881 cgggtgcgtt ggtaggtaat caggtgagtt tgcactggtc aatgtcgatg attggttatg
    32941 tgggcgcggt gcctgctttt gccgcgttaa tttggtcaat cattatattt cgccgctggc
    33001 cagtgacact cgaagaacag acgcaatagt tgaaaggccc attcgggcct tttttaatgg
    33061 tacgttttaa tgatttccag gatgccgtta ataataaact gcacacccat acataccagc
    33121 aggaatccca tcagacggga gatcgcttca atgccaccct tgcccaccag ccgcataatt
    33181 gcgccggagc tgcgtaggct tccccacaaa ataaccgcca ccaggaaaaa gatcagcggc
    33241 ggcgcaacca tcagtaccca atcagcgaag gttgaactct gacgcactgt ggacgccgag
    33301 ctaataatca tcgctatggt tcccggacca gcggtacttg gcattgctag cggcacaaag
    33361 gcaatattgg cactgggttc atcttccagc tcttccgact tgcttttcgc ctccggtgaa
    33421 tcaatcgctt tctgttgcgg aaagagcatc cgaaaaccga taaacgcgac gattaagccg
    33481 cctgcaattc gcagaccggg aatcgaaatg ccaaatgtat ccatcaccag ttgcccggcg
    33541 taatacgcca ccatcatgat ggcaaatacg tacaccgagg ccatcaacga ctgacgatta
    33601 cgttcggcac tgttcatgtt gcctgccagg ccaagaaata acgcgacagt tgttaatggg
    33661 ttagctaacg gcagtaacac caccagcccc aggccaattg ctttaaacaa atctaacatt
    33721 ggtggttgtt atcctgtgta tctgggttat cagcgaaaag tataaggggt aaacaaggat
    33781 aaagtgtcac tctttagcta accttgcatc gcattgacca aaacttgaac cgatttagca
    33841 aaacgtggca tcggtcaatt cattcatttg acttatactt gcctaggcaa tattatcccc
    33901 tgcaactaat tacttgccag ggcaactaat gtgaaaagta ccagcgatct gttcaatgaa
    33961 attattccat tgggtcgctt aatccatatg gttaatcaga agaaagatcg tctgcttaac
    34021 gagtatctgt ctccgctgga tattaccgcg gcacagttta aggtgctctg ctctatccgc
    34081 tgcgcggcgt gtattactcc ggttgaactg aaaaaagtgt tgtcggtcga cctgggagca
    34141 ctcacccgta tgctggatcg cctggtctgt aaaggctggg ttgaaaggtt gccgaacccg
    34201 aatgataagc gcggcgtact ggtaaaactt accaccagcg gcgcggcaat atgcgaacaa
    34261 tgccatcaat tagttggcca ggacctgcat caagaattaa caaaaaaact gacggcggac
    34321 gaagtggcaa cacttgagca tttgcttaag aaagtcctgc cgtaaacaaa aaagaggtat
    34381 gacgatgtcc agacgcaata ctgacgctat taccattcat agcattttgg actggatcga
    34441 ggacaacctg gaatcgccac tgtcactgga gaaagtgtca gagcgttcag gttactctaa
    34501 atggcacctg caacggatgt ttaaaaaaga aaccggtcat tcattaggcc aatacatccg
    34561 cagccgtaag atgacggaaa tcgcgcaaaa gctgaaggaa agtaacgagc cgatactcta
    34621 tctggcagaa cgatatggct tcgagtcgca acaaactctg acccgaacct tcaaaaatta
    34681 ctttgatgtt ccgccgcata aataccggat gaccaatatg cagggcgaat cgcgcttttt
    34741 acatccatta aatcattaca acagctagtt gataacgtga caacgtcact gaggcaatca
    34801 tgaaaccact ttcatccgca atagcagctg cgcttattct cttttccgcg cagggcgttg
    34861 cggaacaaac cacgcagcca gttgttactt cttgtgccaa tgtcgtggtt gttcccccat
    34921 cgcaggaaca accaccgttt gatttaaatc acatgggtac tggcagtgat aagtcggatg
    34981 cgctcggcgt gccctattat aatcaacacg ctatgtagtt attgtcaggc tctgatcaca
    35041 gagcctgaca tctccgtaat atcttcctca agtctcaaat attttcgcca ttgttggcga
    35101 tgagatcccg ataccagtaa aacgacgctt tacgtatccg ttccagcgtt cccttccctt
    35161 cgttgtcttt atcgacataa atcattccgt agcgcttttt catttcccct gttccggcag
    35221 aaaccaggtc aatgcagccc cacggggtgt agccaattaa gtcaacacca tcttcaacta
    35281 cggctttttt catttcccga atatgggaag caaagtaatc aatgcgatag tgatcgttca
    35341 ccgtgccgtc agcttgtctc tggtcaaccg caccaaatcc attttcgaca ataaacagcg
    35401 gcaactggaa atgatcccag aaccagttga gtgaataacg tagccctgcc ggatcaattt
    35461 gccatcccca ttcggatgta tcgatataag ggttgctgac caaatctcgt ggttcaacat
    35521 aatccagttg cgggttatcg ggcgaaaatt gtgtcgtaaa agacatgtag tagctaaagc
    35581 cgataaagtc gacacaacca ctggcaagaa tcgcgttatc ttctggtgtg atatcgaggt
    35641 tgaatccttt cctggcaaag taattcagca tatgttgcgg ataatatcca cgagtatgaa
    35701 catcagtaaa ccagtaacga cgatgcattg ctttcgtggc catcatcata tcgttgggtg
    35761 cacacgtcag aggatagatg ggacacatgg cgatcataca gccaatgtta aattcaggat
    35821 tgatcgattt tccagtctgt accgccaggg cactggcaac taactcgtaa tgtaccgcct
    35881 ggtacattat ttgttcgcgc tcattgatat cttcctctgg cgaatacaag ataccggaat
    35941 tagtaaatgg acacaggctt tcgctgaaat tcacctgatt attgatttcg ttaaacgtca
    36001 tccagtactt tactttttct ttatagcgcg tgaagaccgt tgatgcgaag cggataaaaa
    36061 agtcgatcag tttacggttt cgccagccac catattttgt caccagatga taaggcatct
    36121 caaaatgtga aagcgtcacc acaggttcca ttccctgctt aaggcattca tcgaacagat
    36181 catcataaaa ttgtaaaccc tcttcattcg gctcctgttc gtcaccttgc ggaaagattc
    36241 gtgtccaggc aatggaagtt cgaaagcatt tgaatcccat ctcggcaaat aactgaatat
    36301 ctgttttata gcgatgataa aaatcaattg cttcatgatt gggataatta agcccgtcga
    36361 taacgccttc tgtcacttca cgcggcaccc cgtgagcgcc agcagtcatc acatcagcga
    36421 tgctgatgcc ttttcctcct tcattccagc caccttccaa ctgatgcgcg gctaccgcgc
    36481 cgccccataa aaaacctttt ttaaatcctg acatacacaa ctccttaact aaaatagatt
    36541 accaccagac ttccgcctgg atgccggcca taaactcgtc tttgctgttc tcattaaact
    36601 taaaattcga taattcgtta tccagaatat tgatatacgt tccatagaag cgaatttctg
    36661 gtcgtgaacc taaaatgctt tcacccactt tcaatgcatg ccagagtgtc gttttataag
    36721 ccgattcatt tagtgttaca ccctgctgag ttttgttctg ttgcttaaac cagcctaatt
    36781 caagccccgt ctgattccat gtattccaga tccaggccgg tcttattaca gtgcgaatac
    36841 tgtcaaaatc actatgagca ccactttcat aactataaac atcttcgccg tgagaataga
    36901 caagcgcgtt agccataata atattgtcag taagatacat ctcgccctga gagattaaac
    36961 gccaggcgat cccattggta tgatcaccat agtaatagcg accatgcgcc atcgtattac
    37021 tggcatctga gaaactggca aaactgctgg cataggaatt attggcaacc tgtaacgtaa
    37081 attcattaaa cgtatcgcgt tgcaggtttt gccgtaaaac agaagtcagc atccagctat
    37141 ctttcatttc aaaataactg ttgtcatttt cgttatcttg ttgttgatcc gttttattag
    37201 gtgcggaata tttagccatt aatgataatg tcgcatcatc ccataacggg atattgcgat
    37261 aacgaacatc cacagaattg gtattcatct ggctggtacg cgaaaaatca cgagagtaaa
    37321 catcgacatc atcacggctt aaggacatat caaacagccc tacaccaagt gcccagtttt
    37381 caatccccac acccgcggcg acatccgtgg ttaaggtttt ccagtccagc atctggatct
    37441 catattgcgg gagtttatgt ttgccgaccc agaagtctgc ctctggtgcg aagggtaaaa
    37501 aacctcgcgt tgtcaggtaa atatcgctga actgcatgat attttcattg gcactgtcac
    37561 caaaccaggc atcgttatac tgctcaccca cgttgccatc ataggtaacg accgcatttg
    37621 ccgttttacc gtcctgatta taaacacgct gatttaaggt caggtcaaac caaccgctca
    37681 tctcattacc aaaacgtccc agagaacccg ctgcataagt ttgtggtgag ccgtgattac
    37741 cagtacccca gcctgagcgg aagtacccct gatagctgaa cccaatatca tcctttatat
    37801 atttactgat atctttcagg gtcacgcttt cgatagtggt tttgtcgcct ttactttcaa
    37861 taacggcaac ttgctgcgat ccatttatag tatgcgctgc ggtaaacgag ttctgttcac
    37921 cgttttcatt tttgatgtta tcagcgacgg gagatgtcgc tgatatttca gcaagcgagg
    37981 ctgatttata tttgttttcc gtgatgcttt tttgtaaggt cgaaagtcgg gatttatata
    38041 ctcccagttc attctgtgtt gctttcagct cttgtttatt ttgcgacaat tcattttcaa
    38101 gcaattcaag gcgctgctct atggttaatt ttgttgccat cgcgttcaat ggaaacaatg
    38161 ctgtaataat agaaaaagac aaaaggctga cgttaagcgt ctttatattc atgacttatc
    38221 cttaagagta taataatttc ctccagctat cgcactggag gaaaaaatca ggcatggagt
    38281 tcttttctta atgaaataat ttccctggct aaatcctggc ataatattgc attcatcaaa
    38341 tgatcctgtg catgaatcag aattaaatta acttttattt tgccacagcc ttcatcctga
    38401 ctaattaatg cggtctgaat cttatgtgcc tgaagacagg cagattcaga actggccatt
    38461 agctgagttg cgccctgcca gtctttttgc ccggcacaac gtatggcttc catcgcgtca
    38521 gaacgtgcct gccccgcgtt gaccagtaac tccataacaa gttcttcatc tgcaaacatc
    38581 acaatctcct tcctgggtaa atggaattat ccgttagttg tcatgttatt gactttgttg
    38641 gcggcaataa caaaaggtaa atagatcatt gtcgccacac ctaaacataa aaaaccaacc
    38701 agtaaagcca gccagttccc cccggttccg aggaaagcaa ttaaaggtcc gggcgtagtc
    38761 caaggcacgg cataagcaac cggtggaata atttccatcg aaacaaagaa gtaaccaatg
    38821 gcacagttaa caatgggaac cataataaac ggcaccatca tgatggggtt aagtacaata
    38881 ggaaggccaa acattatcgg ttcattgata ttgaaaatac cggggataaa tgacattttt
    38941 gccagatcac ggtattccgc acgcttagaa gcgataaaaa tagccaacaa taaccccaac
    39001 gtcatacctg aaccgccgca gttggcgaat gcatcattaa tagaagtcca ggtaatcgga
    39061 tatggcgcgc cccaggtagt gccatgttga gcggcccagg agagattctc cagattagcc
    39121 tcagaaaaaa cggtttctcg aattgccgat gtggtattag gtccgtggat ccccagcacc
    39181 cacaggaaat tacccacagc ccccaggata attaccgcaa agatattcgt tcccatatgt
    39241 ttgagcggcg tctggattaa tgtgtaaata agatcgttta gtcctgccgg ggatatcagt
    39301 gtcaggcaat aattaagtgc ggaaaagaac accatgacaa aaaatattgg caataaaact
    39361 ttaaatgaac gcgctaccgc aggcggtaca gctgccggca tcgttatggt gatttttggg
    39421 tttcgagcta agcgacaaaa tatttcactg gtgatcaatg caacgataac agcaacaaac
    39481 aacccctgcg cgccgagata tttggtcgtc aggaatgctt gcccatctat catctgatat
    39541 ggcgtataaa caataaaaaa tgctcctatt gccgttaatc cgcataaaag atcatcttgc
    39601 tcatagctaa tcgccatatt cctggcgacc aggaaagcaa tcataattga catgatattt
    39661 acagaaccat tcattaccgg agtaaaaata gcttgtgctt tttcaaggtt ggggaaaatg
    39721 ctattcagat gcagtaatcc ggcaataaaa ccgtctggcg ataatatggc aaagttaatt
    39781 aatataatta atgaacttgc catgataatt ggaaacgtaa aaacgaatcc atctctcacc
    39841 gctgcaacat gtttttgtga gtttaacttg atagcaactg gaacaagaaa acgttccatt
    39901 ccacgttcga atgaggccat taatcccatt tttttatacc tgttgttttg gatatttata
    39961 catcccaata aagcatgtat gccatatcca ttttatgatg tgtgaaaagt tagttcaggt
    40021 aatagtttaa taatattaga ttcttactct tgcagtagtt tcatcgcaaa ttcaagaact
    40081 gcctgtccgt tcatggtgcc gtagtctttc atctcgataa cggctacagg cattttcccc
    40141 tgtgcaacgg cttcaatctc tggtttctga aagcgaactt gcgggccaag taaaacaacg
    40201 tcaacttcgt tatttttaat tttcccttta gcctctgcaa tcgccaatgc ggaaatatta
    40261 acttcaagtg aaatagcgtt agcatgatca atcatacgtt taaccagcat actggttgac
    40321 atgcccgcag cgcaaactaa caatattttt ttcatatttt cccttactgg tatataacag
    40381 attacattgt ttaaatatca tatcccgcag tagctatacg tcctggtaca ttgatcacag
    40441 taatacagtg ataaagttgt tcaacatcag ggtgattatt aaacgactcg gccatacgat
    40501 aaaccaatca gaactcaact ccttgttttc aatggctctt aaaaggtgca aaagtgattt
    40561 ttcaaaagat tgcccgctta cttaaatccg aaatcaatgg caattcatgg catgttggtg
    40621 atttgttgcc gtcagaagcg gaactcgctg ttcgttataa tgtttcgcgt aataccctgc
    40681 gtaaggcatt atccttgctg gaaggcgaag gaattattca cagaaagcat ggttcaggaa
    40741 catacattca aaaaaagaat tttgttgcac acattgatca catgaacagt ttcagtgaaa
    40801 ttgcgcataa aagcggcaaa gaggcaggga gtcagattat gaaatttgaa gtgcaggatg
    40861 cttcacccac tattgcgact gagctgaatt tagtgactgg tgagcaggtt tattacataa
    40921 agagactgcg attcattgag gataatgcag cacaattaga agaaacgtgg atgtcagtag
    40981 cacgttttcc tgatttaacc gtgtcacata tgcaaaaatc caaattttca tatattgaga
    41041 atgaatgcgg gatcaaaatc attggcacct ttgaaacttt ctcccctact tttcctaccc
    41101 cagaaatcgc cagtatttta cggatcagcc cacgggatcc catacttaaa attcagaccc
    41161 aggctgtgga cagtaactct attccgctgg attattcgtt actttacagc aatattttcg
    41221 agttccaggt aaagtacttt ttcccgcgat aaaagcagac gcacagagtg ctgacatcac
    41281 attctgtgcg tatggtttag cctctaacct ttaccgcttt acgccaccgc aagccaaata
    41341 cattgatata cagcccggtc ataatgagca ccgcacctaa aaattgcaga cccgttaagc
    41401 gttcatccaa caatagtgcc gcacttgcca gtccgactac gggcaccagt aacgataacg
    41461 gtgcaacccg ccaggtttca tagcgtccca gtaacgtccc ccagatccca taaccaacaa
    41521 ttgtcgccac aaacgccaga tacatcagcg acaagatggt ggtcatatca atagtaacca
    41581 gactgtgaat catggatgcg gaaccatcga gaatcagcga ggcaacaaag aagggaatga
    41641 ttgggattaa agcgctccag attaccagcg acatcaccgc cggacgcgtt gagtgcgaca
    41701 tgatcttttt attgaagatg ttgccacacg cccaactaaa tgctgcagcc agggtcaaca
    41761 taaagccgag catcgccaca tgctgaccgt tcagactatc ttcgattaac accagtacgc
    41821 caaaaatcgc taaggcgatc cccgccaatt gtttgccatg cagtcgctcc ccgaaagtac
    41881 acgcgccaag cacgatagta aaaaacgcct gtgcctgtaa caccagcgaa gccagtccag
    41941 caggcatacc aaagttaatg gcgcagaaca gaaaggcaaa ctgcgcaaaa ctgatggtta
    42001 atccataccc caagagcaaa ttcagtggta ctttcggtcg tgcaacaaaa aagatggccg
    42061 gaaaagcgac cagcataaag cgcaaaccgg ccagcatcag cggtggcatg ttatgaagcc
    42121 ccactttgat gaccacaaaa tttagccccc atacgaccac taccagtagc gccaacaccc
    42181 catcttttcg cgacattcta ccgcctctga atttcatctt ttgtaagcaa tcaacttagc
    42241 tgaatttact tttctttaac agttgattcg ttagtcgccg gttacgacgg cattaatgcg
    42301 caaataagtc gctatacttc ggatttttgc catgctattt ctttacatct ctaaaacaaa
    42361 acataacgaa acgcactgcc ggacagacaa atgaacttat ccctacgacg ctctaccagc
    42421 gcccttcttg cctcgtcgtt gttattaacc atcggacgcg gcgctacgct gccatttatg
    42481 accatttact tgagtcgcca gtacagcctg agtgtcgatc taatcggtta tgcgatgaca
    42541 attgcgctca ctattggcgt cgtttttagc ctcggttttg gtatcctggc ggataagttc
    42601 gacaagaaac gctatatgtt actggcaatt accgccttcg ccagcggttt tattgccatt
    42661 cctttagtga ataacgtgac gctggtggtg ctcttttttg ccctcattaa ctgcgcctat
    42721 tctgtttttg ctaccgtgct gaaagcctgg tttgccgaca atctttcgtc caccagcaaa
    42781 acgaaaatct tctcaatcaa ctacaccatg ctcaacattg gctggaccat cggtccgccg
    42841 ctcggcacgc tgttggtgat gcagagcatc aatctgccct tttggctggc agctatctgt
    42901 tccgcgtttc ccatgctttt cattcaaatt tgggtaaagc gcagcgagaa aatcatcgcc
    42961 acggaaacag gcagtgtctg gtcgccgaaa gttttattac aagataaagc actgttgtgg
    43021 tttacctgct ctggttttct ggcttctttt gtaagcggcg catttgcttc atgcatttca
    43081 caatatgtga tggtgattgc tgatggggat tttgccgaaa aggtggtcgc ggttgttctt
    43141 ccggtgaatg ctgccatggt ggttacgttg caatattccg tgggccgccg acttaacccg
    43201 gctaacatcc gcgcgctgat gacagcaggc accctctgtt tcgtcatcgg tctggtcggt
    43261 tttatttttt ccggcaacag cctgctattg tggggtatgt cagctgcggt atttactgtc
    43321 ggtgaaatca tttatgcgcc gggcgagtat atgttgattg accatattgc gccgccagga
    43381 atgaaagcca gctatttttc cgcccagtct ttaggctggc ttggtgccgc gattaaccca
    43441 ttagtgagtg gcgtagtgct aaccagcctg ccgccttcct cgctgtttgt catcttagcg
    43501 ttggtgatca ttgctgcgtg ggtgctgatg ttaaaaggga ttcgagcaag accgtggggg
    43561 cagcccgcgc tttgttgatt taagtcgaac acaataaaga tttaattcag ccttcgttta
    43621 ggttacctct gctaatatct ttctcattga gatgaaaatt aaggtaagcg aggaaacaca
    43681 ccacaccata aacggaggca aataatgctg ggtaatatga atgtttttat ggccgtactg
    43741 ggaataattt tattttctgg ttttctggcc gcgtatttca gccacaaatg ggatgactaa
    43801 tgaacggaga taatccctca cctaaccggc cccttgttac agttgtgtac aaggggcctg
    43861 atttttatga cggcgaaaaa aaaccgccag taaaccggcg gtgaatgctt gcatggatag
    43921 atttgtgttt tgcttttacg ctaacaggca ttttcctgca ctgataacgg atcgttgaca
    43981 cagtagcatc agttttctca atgaatgtta aacggagctt aaactcggtt aatcacgttt
    44041 tgttcgtcaa taaacatgca gcgatttctt ccggtttgct taccctcata cattgcccgg
    44101 tccgctcttc caataaccac atccagaggc tcttcaggaa atgcgcgact cacacctgct
    44161 gtcacggtaa tgttgatatg cccttcagaa tgtgtgatgg catggttatc gactaactgg
    44221 caaattctga cacctgcacg acatgcttct tcatcattag ccgctttgac aataatgata
    44281 aattcttcgc ccccgtagcg ataaaccgtt tcgtaatcac gcgtccaact ggctaagtaa
    44341 gttgccaggg tgcgtaatac tacatcgccg attaaatgcc cgtaggtatc attaaccaat
    44401 ttaaatcggt caatatccaa caacattaaa taaagattca gaggctcagc gttgcgtaac
    44461 tgatgatcaa aggattcatc aagaacccga cgacccggca atcccgtcaa aacatccata
    44521 ttgctacgga tcgtcagcaa ataaattttg taatcggtta atgccgaagt aaaagaaagc
    44581 aacccctcct gaaaggcgtc gaaatgcgcg tcctgccagt gattttcaac aatagccagc
    44641 attaattccc gaccacagtt atgcatatgt tgatgggcag aatccattag ccgaacgtaa
    44701 ggtaattcat cgttatcgag tggccccaga tgatcaatcc accgaccaaa ctggcacagt
    44761 ccataagaat ggttatccgt tatttctggc ttactggcat ctctcgcgac cacgctgtga
    44821 aacatactca ccagccactg gtagtgggca tcgatagcct tattgagatt taacaagatg
    44881 gcatcaattt ccgttgtctt cttgatcatt gccactcctt tttcacagtt ccttgtgcgc
    44941 gctattctaa cgagagaaaa gcaaaattac gtcaatattt tcatagaaat ccgaagttat
    45001 gagtcatctc tgagataaca ttgtgattta aaacaaaatc agcggataaa aaagtgttta
    45061 attctgtaaa tcacctctgc attatcgtaa ataaaaggat gacaaatagc ataacccaat
    45121 accctaatgg cccagtagtt caggccatca ggctaattta tttttatttc tgcaaatgag
    45181 tgacccgaac gacggccggc gcgcttttct tatccagact gccgctaatg ttgatcatct
    45241 ggtccggctg aacttctcgt ccatcaaaga cggccgcagg aataacgaca ttaatttcac
    45301 cgctcttatc gcgaaaaacg taacggtcct ctcctttgtg agaaatcaaa ttaccgcgta
    45361 gtgaaaccga agcgccatcg tgcatgtttt ttgcgaaatc aacggtcatt ttttttgcat
    45421 catcggttcc gcgatagcca tcttctattg catgaggcgg cggtggcgct gcatcctgtt
    45481 ttaaaccgcc ctggtcatct gccaacgcat aaggcatgac aagaaaactt gctaatacaa
    45541 tggcctgaaa tttcatactg actccttaat tgcgtttggt ttgacttatt aagtctggtt
    45601 gctattttta taattgccaa ataagaatat tgccaattgt tataaggcat ttaaaatcag
    45661 ccaactagct gtcaaatata cagagaattt aactcactaa agttaagaag attgaaaagt
    45721 cttaaacata ttttcagaat aatcggattt atatatttga aaattattat attggacgag
    45781 catacagaaa aagcaaatca cctttacata taaaagcgtg gacaaaaaac agtgaacatt
    45841 aatagagata aaattgtaca acttgtagat accgatacta ttgaaaacct gacatccgcg
    45901 ttgagtcaaa gacttatcgc ggatcaatta cgcttaacta ccgccgaatc atgcaccggc
    45961 ggtaagttgg ctagcgccct gtgtgcagct gaagatacac ccaaatttta cggtgcaggc
    46021 tttgttactt tcaccgatca ggcaaagatg aaaatcctca gcgtaagcca gcaatctctt
    46081 gaacgatatt ctgcggtgag tgagaaagtg gcagcagaaa tggcaaccgg tgccatagag
    46141 cgtgcggatg ctgatgtcag tattgccatt accggctacg gcggaccgga gggcggtgaa
    46201 gatggtacgc cagcgggtac cgtctggttt gcgtggcata ttaaaggcca gaactacact
    46261 gcggttatgc attttgctgg cgactgcgaa acggtattag ctttagcggt gaggtttgcc
    46321 ctcgcccagc tgctgcaatt actgctataa ccaggctggc ctggcgatat ctcaggccag
    46381 ccattggtgg tgtttatatg ttcaagccac gatgttgcag catcggcata atcttaggtg
    46441 ccttaccgcg ccattgtcga tacaggcgtt ccagatcttc gctgttacct ctggaaagga
    46501 tcgcctcgcg aaaacgctgc ccattttcac gcgttaatcc gccctgctca acaaaccact
    46561 ggtaaccatc atcggccaac atttgcgtcc acagataagc gtaataacct gcagcatatc
    46621 cgccaccaaa aatatgggcg aaataactgc tgcgatagcg tggcggtata gcaggaagat
    46681 ccatattttc cgccaccagc gcccgcaatt caaaatcatc gacatcctgc attgcttcgt
    46741 tttcttccag gcaatgccag cgcatatcga gaagtgcggc gctaagcagt tcgctcatct
    46801 catacccttt gttgaacagg ctggcattac gcattttctg ttgcagttcg tcaggcattg
    46861 ctgccccgct ctgataatgc cgggcgtagc gagcgaatac ctgcggatgc gttgcccagt
    46921 gttcgttgat ttgcgacgga aattcgacaa aatcacgcgg cgtgttggtg ccggaaagcg
    46981 tggcataacg ctggcgggca aaaaggccgt gcagcgtatg accaaattca tggaataagg
    47041 ttattacatc atcccagagt aacaacgcag gctcaccggc agcgggtttc tgataattgc
    47101 aaacgttata aattaccgga tgcgtttcat taagcgttga ttgctcaaca aaattgccca
    47161 tccatgcacc gccgcttttt gaatcacggg cgaagaaatc accgtaaaat aacgccagtc
    47221 ccacgccatt atgatcaaaa atttcccaca cacgaacgtc aggatggtag acaggaatat
    47281 caaaacgttc gacaaactta ataccgaaga gctgattcgc ggtccagaat acaccttcat
    47341 tcaacaccgt gtttaattca aaatatggct tgagctgcgc ctcatcaaga tcaaatttct
    47401 cccgccgtac ctgttcggca taaaatgccc agtcccacgg ctgcgcgcta aacccgcctt
    47461 gctgcttatc gataaccgcc tgtatggagg ctaattcatc gctagcacgt tgacgcgccg
    47521 ctggaacaat ttcccgcata aagttgagtg ctgcttcagg tgtttttgcc atctgatcgg
    47581 cgattttcca tgcggcataa tgaggaaaac caagcagttt cgcctgctgt gcgcgaatct
    47641 ctaccagacg ttgaatgata gcgcgggtat cattgccatc atttttttcc gctcgcgtcc
    47701 agcccgcaat aaacagtttt tcacgcgtcg cacgatcgcg catttcggca agcgccggtt
    47761 gttgggtggt attcagcagc ggaatcagcc atttgttatc cagacctttc tcgcgagccg
    47821 ccactgccgc cagcgcaatc tcttgctcac tcattcctgc cagctgcgcg atatcgttca
    47881 caaccagacc gccggattta tttgctgcaa gtaaccgctg gttaaactgg ctggtcaggg
    47941 tcgcagcttc tgtattcagt acttttaatt ttgctttatc agcttgcgca agtttggctc
    48001 cggcaaggac aaaacgttga tgaataacct ccaccaggcg gatggattca ctatcaagcc
    48061 ccagggattc acggcgctgc cagacagcat ctacccgcgc gaataattca ccgttcagat
    48121 agatatcatt agccagttcc gccagttcag cggaaaactg ttcatcaaga cgctgtaatt
    48181 catcattggt atgcgccgca gtcatcgcaa aaaagacgct ggtaacgcgg gtaagtaatt
    48241 ctccgctttg ttccagtgcc agaatagtat tgttgaaatc aggcgtttgc gggttaagcg
    48301 cgatggcagc aatttctgcc cgcttttgct gcattccctc atcgaatgcc gggcgatagt
    48361 gatgattggc aatttgatca aaatgaggag ccagatacgg cagtgtgctt tgcacaagga
    48421 aaggattcat tgttgtcatt ttcttctcct gaacgcgagg tgttccatag cgtaggctta
    48481 ctgataacgt agtgcaatct tgcaaaccag tattacccgc tcttaagcat cacgtgctat
    48541 gttattgaca cacaaaagcg ttgaggaaca gtgagatgat cgttttagta actggagcaa
    48601 cggcaggttt tggtgaatgc attactcgtc gttttattca acaagggcat aaagttatcg
    48661 ccactggccg tcgccaggag cggttgcagg agttaaaaga cgaactggga gataatctgt
    48721 atatcgccca actggacgtt cgcaaccgcg ccgctattga agagatgctg gcatcgcttc
    48781 ctgccgagtg gtgcaatatt gatatcctgg taaataatgc cggcttggcg ttgggcatgg
    48841 agcctgcgca taaagccagc gttgaagact gggaaacgat gattgatacc aacaacaaag
    48901 gcctggtata tatgacgcgc gccgtcttac cgggtatggt tgaacgtaat catggtcata
    48961 ttattaacat tggctcaacg gcaggtagct ggccgtatgc cggtggtaac gtttacggtg
    49021 cgacgaaagc gtttgttcgt cagtttagcc tgaatctgcg tacggatctg catggtacgg
    49081 cggtgcgcgt caccgacatc gaaccgggtc tggtgggtgg caccgagttt tccaatgtcc
    49141 gctttaaagg cgatgacggt aaagcggaaa aaacctatca aaataccgtt gcattgacgc
    49201 cagaagatgt cagcgaagcc gtctggtggg tgtcaacgct gcctgctcac gtcaatatca
    49261 ataccctgga aatgatgccg gttacccaaa gctatgccgg actgaatgtc caccgtcagt
    49321 aatttttata cccggcgtaa ctgccgggtt attgcttgtc acaaaaaagt ggtagactca
    49381 tgcagttaac tcactcacaa gcaagaacga atgaccgtcg aaacgcaact taatcccaca
    49441 cagcctgtca atcagcagat ttatcgtatt cttcgtcgcg acattgtcca ttgcctgatt
    49501 gcaccaggca caccgttgtc ggaaaaagaa gtttctgttc gtttcaatgt gtcacgccag
    49561 ccggttcgtg aagcctttat taaactggcg gaaaacggcc tgattcaaat tcgtccgcag
    49621 cgtggcagct acgtcaacaa aatttccatg gcccaggtgc gaaacggcag ttttatccgt
    49681 caggccattg agtgcgcggt ggcgcgtcgg gcggcgagca tgattaccga aagccagtgc
    49741 taccaactgg aacaaaatct tcaccagcaa cgcattgcca ttgagcgcaa gcaactggat
    49801 gatttttttg aacttgatga caacttccat caactcctga cgcagattgc cgactgtcaa
    49861 ctggcgtggg ataccattga gaacctgaaa gcgaccgttg atcgcgtgcg ctatatgagt
    49921 ttcgaccatg tttctccacc agaaatgctg ttacgccagc atcttgatat tttctctgcc
    49981 ctgcaaaaac gtgatggcga tgcggtagaa cgtgcaatga cgcaacattt gcaggaaatc
    50041 agcgaatccg tgcgccagat ccgccaggaa aacagcgact ggtttagcga agagtaattc
    50101 atttactctc atcccatccg ggatgagagg cttttccccc cgccttacgg ctcatgcatg
    50161 catcaaaaaa gatgtgagct tgatcaaaaa caaaaaatat ttcactcgac aggagtattt
    50221 atattgcgcc cgttacgtgg gcttcgactg taaatcagaa aggagaaaac acctatgacg
    50281 acctacgatc gtaaccgtaa cgcaatcacc actggcagcc gtgttatggt tagcggcacc
    50341 ggtcacactg gcaagatcct gtcgattgat actgaaggtc tgaccgctga gcaaatccgc
    50401 cgcggaaaaa ccgtagttgt tgaaggttgt gaagagaaac tggcacctct ggacctgatt
    50461 cgtctcggca tgaactaagt gtgtgaatgc cgccgatggc ggcattgctt tttttacttc
    50521 acggaatatt tcgccacggt cgctttcgcg ccatgcgcta ataaagacaa gtacgcttcc
    50581 gtcacttttg cagtaaacaa gctatcgtct ggcaaatcat caccaaagat tgccttaatc
    50641 gccagcaatg actggacgcg cgctttccct tcggcactac tttgtacagc cttctgaata
    50701 acaggtaaca gtgggtcact gatttctatc ggatttccct gttcatcaac accaccgaca
    50761 taacgcatcc aacccgcgac gcccagcgcc agcagatcga acttgctgtc atgcgccaga
    50821 tgccagcgaa cagaatccaa catccgctgt ggcaatttct ggctgccatc catcgcaatc
    50881 tgccaggttc gatgacgtaa cgccgggttg ctatagcgtg caattaatcg gttagcgtaa
    50941 tcctgcaaat caacgccctg cactttcagc gtcggcgctt gttcctgcaa catcaagcca
    51001 tacgccgcat gacgataatg ttcatcttcc atgcagtcat taatgtgctg atatccggca
    51061 agatacccca gatacgccag gaatgaatga ctgccgttga gcatgcgcaa cttcatctct
    51121 tcataaggca gcacatcgct aaccagttcg gctcccgctt tttcccattc cggacgtccg
    51181 gcaacaaagt tatcttctat tacccactgg cggaaaggtt cacaggcaac gcccgcagga
    51241 tcgcgcacac cggtaagttg ttcgattttc gccagcgtat cctctgtcac tgcgggcaca
    51301 atacggtcca ccattgttga tgggaaagtc acgttatctt cgatccattg tgccagtttt
    51361 acatcaacgg cttgcgcgta ggaagtgaca acatcacgca taacatgacc gttttctggc
    51421 atgttgtcac atgacatgac ggtaaatgcg ggaagtcctg ccgctttacg gcgagccagc
    51481 gcctcaacaa tcacccctgt tgctgttttc ggctggtggg gattttgcac gtcggcagcg
    51541 accatcgggt gatcgagcat taactgtccg gtcgccggag agtggaaata ccctttttcg
    51601 gtgattgtca gagagacaat cgcgatttgc ggttcacaca tcgcagccaa cacggtttct
    51661 aagccatcca tctgtacgtg caaggctttt ttaacgacgc caacgacgcg agccgtccac
    51721 gcatcggccg acatttccgc aacggtataa agattatctt gctgttgtaa atcggcaatt
    51781 tgctgttcgc cgccgattaa gttgacctaa taatatcccc agtcactgaa atgttctgta
    51841 gcaagaatat cggcatacac gccctgatgc gcacggtgaa atgcaccaaa gcctaaatga
    51901 acaattcttg gggccaggtt attacgatca taaacaggga gtgtcgcttt tgctgataac
    51961 aaattatttc ccataacaat tccttaaatt taaatatagc aagctacatg ttttgttata
    52021 tgaataaaaa tcccctctcc ggtaagagaa gggattgagg atttacagac ttctggaagg
    52081 ttgcgcagct cttacaacac gcggttgatc ttccgcagcg tcttccagcg cacttaaatc
    52141 acggtctttc acctctggca ttttcagcgc agagattaaa ccaatcactg aatatgccat
    52201 gatcataatg gcgatcggat accaggattc cgtcatggtg cagaaaatac ccgccaggat
    52261 aggaccaaaa ccggaagcga taagaccacc aatttcttta gaaatagcca tccgggtaaa
    52321 gcggttttta cagccgaaca tttctgccat ggtaatgttt tccagagcaa ataatcccag
    52381 caccgcacag ttatgaatca caatcagtgc aaccataatg gtgctcgggg catagctttt
    52441 atctacaatg atagaaagca ttggccatgc cagcacaatc gcggaggtat tcataataat
    52501 atacgggatc cggcgaccaa ttttatcgga taaccaacca aggaacggaa tggtcataaa
    52561 gccgagaatc gaactaatca tcaatgcatc tgttggaatt gctttgttaa acaataacgt
    52621 ctgcactaaa tagcctgcaa ggaaagtctg aattaaacct gagttaccag cctgaccaaa
    52681 acgcagccct gttgccagcc agaaggattt gctctggaac atgctaccag caggtgcagg
    52741 ttttgctgtc ggttggttgc tgtcattaac cttctcaaag accgggcttt ctttcagatt
    52801 catacgcaac cagatagcaa agaccatcac gacaacgctc gccaggaacg gtatacgcca
    52861 tccccacgcc agcagttcct ctttactgag aatgaagaac ataaaggccc agattgccgt
    52921 tgcgctcaag gttccgcagt tagttcccat agctacaaat gaggagataa ttccgcgctt
    52981 accttttggc gcatattccg ccagcatcgt accggcaccg gaaatttccg cacctgcacc
    53041 caccccctga ataatacgca gcgtcaccag caagatgggt gcaaaaacac caatctgtgc
    53101 ataggtcggt aacacaccaa ttaaggtggt acagatcccc atcatggtga tggtaataaa
    53161 gagcactttt ttacgcccta ttctgtcgcc cattttgccg aaaataaatg ctccgacaat
    53221 acgcgccaca taacctgcac cgtaggttcc cattgccaga attaacgcca ttgccgttga
    53281 tgattcagga aaaaatattt catgaaacac taacgctgcg ccgagcgaat ataactggaa
    53341 atccataatt catagatgtt ttttactatt ctgtgggttt ttgggtgttt tctaagtttt
    53401 ttcagatggt tgtatttttt ctaaaaatcc ctaatctcga ttttgctgtt tatttgaggc
    53461 ctttttatgt cccatatatg ccccacagat accccgcagc caaaatcaac aaaatgccaa
    53521 aaggttctgt tcctgccctg caacaagaaa tgctgcgacg tgtcagtaaa cgttatgacg
    53581 atgcagaagt gatcatcaaa tccaccagca acaatggcct ttcagttact cacaccgccg
    53641 ataaagattc tgcaaaaact tttgttcagg agacgctgaa agatacccgg gagtctgctg
    53701 acgagtggtt tgttcgctaa ttaacgagta aaatcagtaa cggctggaaa tcattcaata
    53761 ctcacactat ctaaaagttc accagccaac agcggtaagt tctttcatac gacgtgccgc
    53821 ggatcctatt attctagtat gaaatcccta accgatttca aattctccag actgctcaga
    53881 ttctctttta tcccacgctg gcgctgataa atctcgtcat tgcaatcgac ctgcgctatc
    53941 gctgccgcag ttcttccagt ttctgcatcg ataactccat cttctgagca ataaacctca
    54001 cctatgcaat atcttatgtc aattatttca attgcattaa tatcttgaat ggattacata
    54061 gagttaatgt atccagtact ccctattctc ttgcatataa tacatgttgc aacttacatc
    54121 tcagcgctat gaaaaaacac cacctctctc tttatgaaat tctggattta ccaagcgcta
    54181 atttatcatt tcaatctacc tttaagtatt gcatttatct ccctacgagg tcatacttta
    54241 ggaagttaaa tatgaatgat aatataccta cagcgcgaaa tcacaaacaa tcgacttgta
    54301 ttacagaaaa aaacatgcct atatttttaa acttcacagc aggcagtatc ttacctgaga
    54361 atgagctagc atctttacgt tatattgtgc agcaaaatca aaatgatact gtaatcataa
    54421 aagaacgtta taaaatggat atccgttata tcgaatcagt caatggtttt acagtaaatc
    54481 ctgtatgcag taatcatttc tccatattta tggcgagaca aaacactatt gctcgcaacc
    54541 tggaacagca gatcaacaac ggacgaagtt ttgcacaaat atctcaggat tttatgcttc
    54601 aattatcttc aaatatagga tggaaaaaag gggccgaaaa cgcccttaaa aataaaatcc
    54661 attctcattc atttgttgta aatcctgatg aattctcttg cgacacacaa tttcttaagt
    54721 gcccaataac attatgcgtt ccagaaaaag gggtttttgt caagaacgca ctgaactcca
    54781 acatatgcac tctttatgat aagtctgcgt tcatgaatct cacaagagaa catctacccc
    54841 accctctcag cagggaaaag atagtaaaag aaatgattat tgaaaggaat atgtgttatt
    54901 ttgacaccat aagtcagcat ttcataatta tggatgcaga ccaacagaaa cagcattgta
    54961 aataaaatgt aataattaca tactattagt gattctcatg catcgtaagc ggctcgccag
    55021 aaccgtattg atatttactg agcgctcaga tcaactttcc atggcaacag atcgcgtacc
    55081 cggtttgccg gccagtcctg gatatgctcc cgccgacaat attaatggcc aggaaatgtt
    55141 taaaacaatg attctgtttc ctaaccatca agtgtatatg ctggctcaat tactcaatat
    55201 ctatgggttg agttctaccc aaagtggctc tgtagtcgct tcttcttaca gtatgttcag
    55261 gtgttgcagg cacagttgtg gagcgtagat gtgttgttgg tttaccatgc tctggtacat
    55321 aaaaaacgcc agtgccatgg taacctgata tagaaacgtt aattccgcga cgttcaaact
    55381 cggcatagac gtgttctgct aaagaactct tttgaccaaa taatgccctg gccaaccagc
    55441 cgttattcat atttgcggat ttctctattt catcaggaga gaagtctttg ttttttaata
    55501 tgttggctga gttacaggat gttaatctga tatcatcaat ctcatgaaga ttatgttgaa
    55561 caatgcggtc gacaatatct gtcggcgata aaaattcatc tccacact
//
LOCUS       DAZUDJ010000026        55561 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.026, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000026 DAZUDJ010000000
VERSION     DAZUDJ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 55561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55561
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.026"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            452..1088
                     /locus_tag="ACHY1N_002143"
                     /pseudo
     CDS             452..1088
                     /locus_tag="ACHY1N_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416774.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1191..1694
                     /locus_tag="ACHY1N_002144"
     CDS             1191..1694
                     /locus_tag="ACHY1N_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HFS4044451.1"
                     /translation="MGMIGYFAEIDSEKINQLLESTEKPLMDNIHDTLSGLRRLDIDK
                     RWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDGIDGFLGLTWNQELAATIDRLEA
                     LDRSELRKKFSIKRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRMLRQGNH
                     ALTVIVG"
     gene            complement(1761..3218)
                     /gene="nuoN"
                     /locus_tag="ACHY1N_002145"
     CDS             complement(1761..3218)
                     /gene="nuoN"
                     /locus_tag="ACHY1N_002145"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HFS4044452.1"
                     /translation="MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNK
                     DEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQY
                     SAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM"
     gene            complement(3225..4754)
                     /gene="nuoM"
                     /locus_tag="ACHY1N_002146"
     CDS             complement(3225..4754)
                     /gene="nuoM"
                     /locus_tag="ACHY1N_002146"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HFS4044453.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMGLTLALSL
                     QLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAV
                     LCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYNATGVWTFNYEELLNTPMSSG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFA
                     VATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTR
                     P"
     gene            complement(4918..6759)
                     /gene="nuoL"
                     /locus_tag="ACHY1N_002147"
     CDS             complement(4918..6759)
                     /gene="nuoL"
                     /locus_tag="ACHY1N_002147"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HFS4044454.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALV
                     TAFIGVDFFANGEQAYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMY
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKG
                     VTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLA
                     AWLWLGKRTLVTSIANSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     SMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(6756..7058)
                     /gene="nuoK"
                     /locus_tag="ACHY1N_002148"
     CDS             complement(6756..7058)
                     /gene="nuoK"
                     /locus_tag="ACHY1N_002148"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HFS4044455.1"
                     /translation="MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(7055..7609)
                     /gene="nuoJ"
                     /locus_tag="ACHY1N_002149"
     CDS             complement(7055..7609)
                     /gene="nuoJ"
                     /locus_tag="ACHY1N_002149"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HFS4044456.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAI
                     MLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRKDDSAKRKTEEHA"
     gene            complement(7621..8163)
                     /gene="nuoI"
                     /locus_tag="ACHY1N_002150"
     CDS             complement(7621..8163)
                     /gene="nuoI"
                     /locus_tag="ACHY1N_002150"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HFS4044457.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(8178..9155)
                     /gene="nuoH"
                     /locus_tag="ACHY1N_002151"
     CDS             complement(8178..9155)
                     /gene="nuoH"
                     /locus_tag="ACHY1N_002151"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HFS4044458.1"
                     /translation="MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVP
                     VSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ"
     gene            complement(9152..11878)
                     /gene="nuoG"
                     /locus_tag="ACHY1N_002152"
     CDS             complement(9152..11878)
                     /gene="nuoG"
                     /locus_tag="ACHY1N_002152"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006120 - mitochondrial electron transport,
                     NADH to ubiquinone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HFS4044459.1"
                     /translation="MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGE
                     ENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNAGSLE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVV
                     LENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPE
                     LAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEG
                     NNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTS
                     VPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGT
                     RVSFSYDGNTVTLPVEIAEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ"
     gene            complement(11931..13268)
                     /gene="nuoF"
                     /locus_tag="ACHY1N_002153"
     CDS             complement(11931..13268)
                     /gene="nuoF"
                     /locus_tag="ACHY1N_002153"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HFS4044460.1"
                     /translation="MKNIIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVNQVKDAGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGAWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTTAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIN
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(13265..13765)
                     /gene="nuoE"
                     /locus_tag="ACHY1N_002154"
     CDS             complement(13265..13765)
                     /gene="nuoE"
                     /locus_tag="ACHY1N_002154"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HFS4044461.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEMHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIHAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHINGY
                     QGIQAALEKKLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHAHLTPEAIPE
                     LLERYK"
     gene            complement(13768..15570)
                     /gene="nuoC"
                     /locus_tag="ACHY1N_002155"
     CDS             complement(13768..15570)
                     /gene="nuoC"
                     /locus_tag="ACHY1N_002155"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030964 - NADH dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HFS4044462.1"
                     /translation="MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHL
                     ISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMM
                     PQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFL
                     NLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLA
                     SYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENF
                     DFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSY
                     AHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(15664..16326)
                     /gene="nuoB"
                     /locus_tag="ACHY1N_002156"
     CDS             complement(15664..16326)
                     /gene="nuoB"
                     /locus_tag="ACHY1N_002156"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HFS4044463.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLND
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(16342..16785)
                     /gene="nuoA"
                     /locus_tag="ACHY1N_002157"
     CDS             complement(16342..16785)
                     /gene="nuoA"
                     /locus_tag="ACHY1N_002157"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HFS4044464.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     SKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR"
     gene            complement(17416..18354)
                     /gene="lrhA"
                     /locus_tag="ACHY1N_002158"
     CDS             complement(17416..18354)
                     /gene="lrhA"
                     /locus_tag="ACHY1N_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HFS4044465.1"
                     /translation="MISANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLNRVSSVYPKLALDVRVKRNAYMAEMLESQEVDLMVTTHRPSA
                     FKALNLRTSPTHWYCAAEYVLQKGEPIPLVLLDDPSPFRDMVLATLNKADIPWRLAYV
                     ASTLPAVRAAVKAGLGVTARPVEMMSPDLRVLSGVDGLPPLPDTEYLLCYDPSSNNEL
                     AQVIYQAMESYHNPWQYSPISAPEGDDSLLIERDIE"
     gene            19274..20491
                     /gene="alaA"
                     /locus_tag="ACHY1N_002159"
     CDS             19274..20491
                     /gene="alaA"
                     /locus_tag="ACHY1N_002159"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase AlaA"
                     /protein_id="HFS4044466.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDA
                     EHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSL
                     SKFARFLSGYHQL"
     gene            20575..21174
                     /gene="yfbR"
                     /locus_tag="ACHY1N_002160"
     CDS             20575..21174
                     /gene="yfbR"
                     /locus_tag="ACHY1N_002160"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002953 - 5'-deoxynucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HFS4044467.1"
                     /translation="MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQ
                     KLVDMVPEELQDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAK
                     TRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL"
     gene            complement(21233..23065)
                     /locus_tag="ACHY1N_002161"
     CDS             complement(21233..23065)
                     /locus_tag="ACHY1N_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HFS4044468.1"
                     /translation="MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLT
                     VPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTV
                     AGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFR
                     DLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVN
                     GVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPE
                     SELIGKSVREIGFRTRYGLNVVGLKRNGVALEGSLADEPLLLGDIILVVGNWKLIGML
                     AKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLM
                     GKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMM
                     LGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPV
                     SSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF"
     gene            complement(23152..23802)
                     /gene="hxpA"
                     /locus_tag="ACHY1N_002162"
     CDS             complement(23152..23802)
                     /gene="hxpA"
                     /locus_tag="ACHY1N_002162"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpA"
                     /protein_id="HFS4044469.1"
                     /translation="MRCKGFLFDLDGTLVDSLPAVERAWSNWARRHGLAPEEVLAFIH
                     GKQAITSLRHFMAGKSEADIAAEFTRLEHIEATETEGITALPGAIALLNHLNKAGIPW
                     AIVTSGSMPVARARHKIAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
                     VEDAPAGVLSGLAAGCHVIAVNAPADTPRLNEVDLVLHSLEQITVTKQPNGDVIIQ"
     gene            complement(23813..24307)
                     /locus_tag="ACHY1N_002163"
     CDS             complement(23813..24307)
                     /locus_tag="ACHY1N_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFS4044470.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQM
                     RELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEAR
                     YLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            complement(24390..24845)
                     /gene="yfbV"
                     /locus_tag="ACHY1N_002164"
     CDS             complement(24390..24845)
                     /gene="yfbV"
                     /locus_tag="ACHY1N_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminus macrodomain insulation protein YfbV"
                     /protein_id="HFS4044471.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMT
                     RYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAI
                     LNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            25183..26385
                     /gene="ackA"
                     /locus_tag="ACHY1N_002165"
     CDS             25183..26385
                     /gene="ackA"
                     /locus_tag="ACHY1N_002165"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HFS4044472.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARI
                     KWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            26460..28604
                     /gene="pta"
                     /locus_tag="ACHY1N_002166"
     CDS             26460..28604
                     /gene="pta"
                     /locus_tag="ACHY1N_002166"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFS4044473.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     TGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIVANYHANTKDA
                     EVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFG
                     GAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVNNVDPAKLQESSPLPVL
                     GAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSL
                     LVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNT
                     NTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAF
                     RYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGV
                     ELGAGIEIVDPEVVRESYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDG
                     LVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQL
                     AEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGP
                     LQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQG
                     MRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ"
     gene            28794..30314
                     /gene="yfcC"
                     /locus_tag="ACHY1N_002167"
     CDS             28794..30314
                     /gene="yfcC"
                     /locus_tag="ACHY1N_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFS4044474.1"
                     /translation="MSAITESKPTRRWAMPDTLVIIFFVAILTSLATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRILTNEAGEPEYHRVQLFTTGDERPGLMNFPFEGLTS
                     GSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPALFILFSL
                     GGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRVKKNPLLSRVHESDRFFREKQAD
                     VEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEIASQFFTMGLVIGIIGVVFRL
                     NGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAI
                     SGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSSVVVIGAQLMGYH"
     gene            complement(30347..30889)
                     /gene="yfcD"
                     /locus_tag="ACHY1N_002168"
     CDS             complement(30347..30889)
                     /gene="yfcD"
                     /locus_tag="ACHY1N_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HFS4044475.1"
                     /translation="MEQRRLASTEWVDIVNEENEVIAQASREQMRAQCLRHRATYIVV
                     HDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFAE
                     HGQFYFEDKNCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKA
                     LALWMKRNAKNEAVETETAE"
     gene            complement(30947..31498)
                     /gene="yfcE"
                     /locus_tag="ACHY1N_002169"
     CDS             complement(30947..31498)
                     /gene="yfcE"
                     /locus_tag="ACHY1N_002169"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311211.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HFS4044476.1"
                     /translation="MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRN
                     ALPEGYAPAKVAERLNEVAHKVIAVRGNCDSEVDQMLLHFPITAPWQQVLLEKQRLFL
                     THGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPKGGNPASYGML
                     DNDVLSVIALNDQSIIAQVAINP"
     gene            complement(31554..32198)
                     /gene="yfcF"
                     /locus_tag="ACHY1N_002170"
     CDS             complement(31554..32198)
                     /gene="yfcF"
                     /locus_tag="ACHY1N_002170"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="HFS4044477.1"
                     /translation="MSKPAITLWSDAHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGE
                     HLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRFAPPTWERIYPLDLENRARA
                     RQIQAWLRSDLMPIREERPTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLVLGQPNL
                     FGEWCIADTDLALMINRLVLHGDEVPERLVDYATFQWQRASVQRFIALSAKQSG"
     gene            32334..32981
                     /gene="yfcG"
                     /locus_tag="ACHY1N_002171"
     CDS             32334..32981
                     /gene="yfcG"
                     /locus_tag="ACHY1N_002171"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HFS4044478.1"
                     /translation="MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFL
                     RISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLF
                     WQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
                     IADIACWPWVNAWTRQRIDLAMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS"
     gene            33038..33400
                     /gene="folX"
                     /locus_tag="ACHY1N_002172"
     CDS             33038..33400
                     /gene="folX"
                     /locus_tag="ACHY1N_002172"
                     /EC_number="5.1.99.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate 2'-epimerase"
                     /protein_id="HFS4044479.1"
                     /translation="MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADK
                     ARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDK
                     LHALRYADSVSMTLSWQR"
     gene            33421..34314
                     /locus_tag="ACHY1N_002173"
     CDS             33421..34314
                     /locus_tag="ACHY1N_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HFS4044480.1"
                     /translation="MNIVITGGTGLIGRHLIPRLLELGHQITVVTRNPQKASSVLGPR
                     VTLWQGLADQSNLNGVDAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINAS
                     DTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
                     LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRG
                     PFNMVSPYPVRNEQFAHALGHALHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRL
                     EEAGFAFRWYDLEEALADVVR"
     gene            complement(34362..35252)
                     /gene="rpnB"
                     /locus_tag="ACHY1N_002174"
     CDS             complement(34362..35252)
                     /gene="rpnB"
                     /locus_tag="ACHY1N_002174"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnB"
                     /protein_id="HFS4044481.1"
                     /translation="MTISTTSTPHDAVFKSFLRHPDTARDFIDIHLPAPLRKLCDLTT
                     LKLEPNSFIDDDLRQYYSDLLWSVKTQEGVGYIYVVIEHQSKPEELMAFRMMRYSIAA
                     MQNHLDAGYKELPLVIPMLFYHGCRSPYPYSLCWLDEFAEPAIAHKIYSSAFPLVDIT
                     VVPDDEIMQHRKMALLELIQKHIRQRDLLGLVDQIVSLLVTGNTNDRQLKALFNYVLQ
                     TGDAQRFRAFIGEIAERAPQEKEKLMTIADRLREEGAMQGKHEEALRIAQEMLDRGLD
                     RELVMMVTRLSPDDLIAQSH"
     gene            complement(35449..36222)
                     /gene="hisP"
                     /locus_tag="ACHY1N_002175"
     CDS             complement(35449..36222)
                     /gene="hisP"
                     /locus_tag="ACHY1N_002175"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HFS4044482.1"
                     /translation="MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGK
                     STFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     STHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFLKGSLK"
     gene            complement(36230..36946)
                     /locus_tag="ACHY1N_002176"
     CDS             complement(36230..36946)
                     /locus_tag="ACHY1N_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4044483.1"
                     /translation="MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFL
                     AIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLI
                     SLFRRAEKRWLQHVKPSSTH"
     gene            complement(36943..37629)
                     /gene="hisQ"
                     /locus_tag="ACHY1N_002177"
     CDS             complement(36943..37629)
                     /gene="hisQ"
                     /locus_tag="ACHY1N_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="HFS4044484.1"
                     /translation="MLYGFSGVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRL
                     SGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVTEAMGVGQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV
                     ILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLFLERR
                     YSVGVKRADL"
     gene            complement(37719..38501)
                     /gene="hisJ"
                     /locus_tag="ACHY1N_002178"
     CDS             complement(37719..38501)
                     /gene="hisJ"
                     /locus_tag="ACHY1N_002178"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HFS4044485.1"
                     /translation="MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNS
                     QGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            complement(38722..39504)
                     /gene="argT"
                     /locus_tag="ACHY1N_002179"
     CDS             complement(38722..39504)
                     /gene="argT"
                     /locus_tag="ACHY1N_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HFS4044486.1"
                     /translation="MKKSILALSLLVGLSAAASSYAALPETVRIGTDTTYAPFSSKDA
                     KGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANETWRSKGVDVV
                     AYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGSSVKDKKYFGDGTG
                     VGLRKDDAELTAAFNKALGELRQDGTYDKMAKKYFDFNVYGD"
     gene            complement(39770..40339)
                     /gene="ubiX"
                     /locus_tag="ACHY1N_002180"
     CDS             complement(39770..40339)
                     /gene="ubiX"
                     /locus_tag="ACHY1N_002180"
                     /EC_number="2.5.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin prenyltransferase UbiX"
                     /protein_id="HFS4044487.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTL
                     SLETDFSLREVQALADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
                     DVINQTVNRVLDQFAITLPEDLFARWQGA"
     gene            complement(40434..41951)
                     /gene="purF"
                     /locus_tag="ACHY1N_002181"
     CDS             complement(40434..41951)
                     /gene="purF"
                     /locus_tag="ACHY1N_002181"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFS4044488.1"
                     /translation="MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAAT
                     NRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLG
                     FDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIDAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG"
     gene            complement(41988..42476)
                     /gene="cvpA"
                     /locus_tag="ACHY1N_002182"
     CDS             complement(41988..42476)
                     /gene="cvpA"
                     /locus_tag="ACHY1N_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HFS4044489.1"
                     /translation="MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGV
                     CFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RA"
     gene            complement(42735..43397)
                     /gene="dedD"
                     /locus_tag="ACHY1N_002183"
     CDS             complement(42735..43397)
                     /gene="dedD"
                     /locus_tag="ACHY1N_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416817.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030428 - cell septum [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_process: GO:0032506 - cytokinetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HFS4044490.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKAGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPTTIAANNTEFEPEPA
                     PVAPPKPKPVEPPKPKVEAPPAPKPEPKPVVEEKAAPTGKAYVVQLGALKNADKVNEI
                     VGKLRGAGYRVYTSPSTPVQGKITRILVGPDASKDKLKGSLGELKQLSGLSGVVMGYT
                     PN"
     gene            complement(43387..44655)
                     /gene="folC"
                     /locus_tag="ACHY1N_002184"
     CDS             complement(43387..44655)
                     /gene="folC"
                     /locus_tag="ACHY1N_002184"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HFS4044491.1"
                     /translation="MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGV
                     LKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPE
                     SAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVD
                     ADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGA
                     LLQRRGVEWNYSVTDHDWAFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENA
                     IRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADA
                     KAEDTVLVCGSFHTVAHVMEVIDARRSGGK"
     gene            complement(44725..45639)
                     /gene="accD"
                     /locus_tag="ACHY1N_002185"
     CDS             complement(44725..45639)
                     /gene="accD"
                     /locus_tag="ACHY1N_002185"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFS4044492.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPEAPREGVVVPPVPDQEPEA"
     gene            complement(45795..46454)
                     /locus_tag="ACHY1N_002186"
     CDS             complement(45795..46454)
                     /locus_tag="ACHY1N_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFS4044493.1"
                     /translation="MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGDKLFS
                     NPDSKIFRRSYLDKTHQFYERHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
                     VIGALLWVLIFTYAGYFFGTLPFIQSNLKLMIVGIIFVSILPGVFEFIRHKRAAARAA
                     K"
     gene            complement(46537..47349)
                     /gene="truA"
                     /locus_tag="ACHY1N_002187"
     CDS             complement(46537..47349)
                     /gene="truA"
                     /locus_tag="ACHY1N_002187"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFS4044494.1"
                     /translation="MSDQQQLPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALS
                     QVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKA
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHN
                     QPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD"
     gene            complement(47349..48362)
                     /locus_tag="ACHY1N_002188"
     CDS             complement(47349..48362)
                     /locus_tag="ACHY1N_002188"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFS4044495.1"
                     /translation="MSEGWNIAVLGATGAVGEALLETLAERQFPVGEIYALARNESAG
                     EQLRFGGKTITVQDAAEFDWTQAQLAFFVAGKEATAAWVEEATNSGCLVIDSSGLFAL
                     EPDVPLVVPEVNPFVLTDYRNRNVIAVPDSLTSQLLAALKPLIDQGGLSRISVTSLIS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEEDFFGRQLAFNMLPLLPDSEGSVREERRIVD
                     EVRKILQDEGLMISASVVQAPVFYGHAQMVNFEALRPLAAEEARDAFAQGEDIVLSEE
                     NEFPTQVGDASGTPHLSVGCVRNDYGMPEQVQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            complement(48428..49564)
                     /gene="pdxB"
                     /locus_tag="ACHY1N_002189"
     CDS             complement(48428..49564)
                     /gene="pdxB"
                     /locus_tag="ACHY1N_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033711 - 4-phosphoerythronate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HFS4044496.1"
                     /translation="MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVR
                     SVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSS
                     LLMLAERDGFSLHDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRS
                     LDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALL
                     TCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSK
                     FIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPG
                     EFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR"
     gene            49663..50658
                     /gene="flk"
                     /locus_tag="ACHY1N_002190"
     CDS             49663..50658
                     /gene="flk"
                     /locus_tag="ACHY1N_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0010468 - regulation of gene expression
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HFS4044497.1"
                     /translation="MIQPISGPPPGQPPGQGDNLPSGAGNQPLSSQQRTSLESLMTKV
                     TSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQ
                     LGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREAT
                     DRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWL
                     QARQTLSQQNTPTLESLQMALKQPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDIL
                     NQLYQRRVKGIDPRDMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWLVR"
     gene            complement(50655..51833)
                     /locus_tag="ACHY1N_002191"
     CDS             complement(50655..51833)
                     /locus_tag="ACHY1N_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4044498.1"
                     /translation="MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     DLGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAA
                     ILPVSAPFKFALLVIGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
                     LAVGAPLGLLIHSHYGFAALAITTMVLPLLAWACNGTVRKVPALAGERPSLWSVVGFI
                     WKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRF
                     GGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQ
                     VRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
                     "
     gene            complement(52117..53337)
                     /gene="fabB"
                     /locus_tag="ACHY1N_002192"
     CDS             complement(52117..53337)
                     /gene="fabB"
                     /locus_tag="ACHY1N_002192"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HFS4044499.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGM
                     RSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLI
                     AGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGF
                     GGTNATLVMRKLKD"
     gene            53496..55502
                     /gene="mnmC"
                     /locus_tag="ACHY1N_002193"
     CDS             53496..55502
                     /gene="mnmC"
                     /locus_tag="ACHY1N_002193"
                     /EC_number="1.5.-.-"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416827.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004808 - tRNA
                     (5-methylaminomethyl-2-thiouridylate)(34)-
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HFS4044500.1"
                     /translation="MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNQLEVRFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEK
                     FPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDEGRVTLDLWFGDINEL
                     TSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRR
                     GLQDAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSAPWFNRTGSSKREAAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFAR
                     RFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVA
                     TNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQNLSRKDDCWLLNFAGDQ
                     QATHSVVVLANGHQISRFSQTSTLPVYSVAGQVSHIPTTPELAELKQVLCYDGYLTPQ
                     NPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKEARCGV
                     RCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALGSRGLCSAP
                     LCAEILAAQMSDEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG"
BASE COUNT        13863 a        15173 c        13887 g        12638 t
ORIGIN      
        1 acacaattag aaataaaaca ctcacaaccc aaaaatagag catccggcaa aagagtgagt
       61 taacatcatt gttaattaat tcgaccagtc agcaaatatg ctgactggtc gaacatagtt
      121 tgctaaacag tcatcactga ctgatgtcag tcacaccatc cgccagttca atcttcgggt
      181 atttccagcg tatctcggca cgcgattgct ggtctgttga tgtagtggat ttttgttgct
      241 gacttttctt accctcagag ttctgccccc tgtcaactca atctgccaat aaataacata
      301 attatatttt tccttatatg aattcctttt taaaatagcg aagccactgt aaaagatact
      361 ttttgtatag atctaacaac cgtaataaaa caaacactca taactcatta taaataatga
      421 taaaataacg tcttttattg ataatttata tatgaaaaaa aatccttttg ttatattatt
      481 tctgatttca ctccctctga ttatttttac caaccctggg tcactgcatt atcgccaacg
      541 ccccgacacg tcagtcctga gcaattagaa aaaacagttc gttatcttac acaaactgtg
      601 catccacgta atgccgacaa tattgataat ctgaataggt ccgtagagta tataaaagag
      661 ttctttgtca gtagcggtgc cagagttacc gcgcagggcg tccccgattg gctattacga
      721 ctctgcgcct ggtagccagg attaccctta cccgcaatgt cctggcttta tcccgatcgg
      781 ggggacttta ttgcctggtc ggcagaatac aggatatcaa cgccgttcgt caggtaaaaa
      841 cggcattgtt atcatcccgg gatttatctg tttattctat gaatgcccca tggtttattc
      901 ccggtattga tttctctgac cacctgaatt attggcaaca cgatattccc gccgtaatga
      961 ttactgacac cgctttttat cgtaataaac aataccactt gcccggtgat acagcagaca
     1021 gattgaatta tcagaaaatg gctcaggtgg tggatggggt tataactttg ttatacaaca
     1081 gtaaataata aaaatttctc gaggcgggtc cagaaaaagc gacatgcaca ttttattttc
     1141 cctcgtttat tttaagatgc gaaacataaa attcaacgga ggaaaaataa atgggaatga
     1201 ttggctattt tgcagaaatt gactcagaaa aaattaacca actgcttgag tctactgaaa
     1261 aacccttaat ggacaatatt catgacactc tttcaggatt acgccgactg gatattgata
     1321 aacgctggga ttttttacac tttgggctga caggcacctc tgcttttgat cccgcgaaga
     1381 atgatccgct gagtcgtgcc gtgcttggtg aacacagcct cgaagatggc atagatggct
     1441 tcctgggatt gacctggaat caggagttag ccgcgacaat cgaccgactg gaagctttgg
     1501 atcgaagtga gctgcgtaaa aagttttcca ttaagcgact caatgaaatg gagatttatc
     1561 cgggagtgac cttttcagaa gagttagagg ggcaactctt tgcttcgatc atgcttgata
     1621 tggaaaagct gattagcgcg tatcgacgta tgctgcgaca ggggaatcat gcgctgacgg
     1681 ttattgttgg gtgatggtgt cagagcgcca aaaaaaaccg ccgaacatgt cggcggcttt
     1741 ctgaattacg aactgacagc ttacatcagc ggcatggcta accgcacaat gctaatcagc
     1801 ggttgtggcc atacacccag caccagtacc aacagtgcag agatcagcac aacgataccg
     1861 cccgcgctgt actgccagtt tgatggtgca tcgcgacccg gttgttccgg ggcgtgaaga
     1921 tacaggctca ccgccacgcg caggtagtag tagaggccga ttgccgaacc gacaaccacg
     1981 gcacccacca gccaccacaa gtgtgcctgg acaccgaccg ccagcacgta gaacttaccg
     2041 ataaagccca gcgtcatcgg gataccggcc agagacagca tcatcaccgt catcactgcc
     2101 gcgaggatcg gacgatgcca gaacagaccg cggtaagaga acagggaatc agcatccggg
     2161 ccacgatacg ggctggacat caggctgacc acgccgaacg cgccgaggct gctgaacaga
     2221 taaccggcca ggtaaacccc taccgcttcc atcgacatct cgccggtttg cagcgcaatc
     2281 agcgccacca gcagatagcc gaggtgagag atagatgagt aaccgagcag acgtttgatg
     2341 ttggtctggc tcaacgccat caggttaccg aagatgatgg aggcaaaggc gataatcgcc
     2401 agtactacgc gaatcgcttc gctgtcaccc accggtgcgt agaggaacag acgcatcacc
     2461 acaccgaaga tagcgatttt gctcgccgtc gccaggaaag tggaaaccgg cgcaggcgcg
     2521 ccctggtata cgtctggcgt ccacaggtgg aacggcacca gagagagttt gaagccgagg
     2581 ccaacaatca tcaggccgaa acctgccagc aacagcggct cgttgagcat accgtcgccg
     2641 aggtttttac ccaacgcgac aaacgacagg tcgccagact gcgcatacac cagcgccata
     2701 ccgaacagca ggaatgaaga cgctgcggca gaaaggatgg tgtatttgat actggcttcc
     2761 agcgaacgtt tctggcggaa agcgtaaccg accaggccaa acagcggcaa agagatcagt
     2821 tcaataccga ggaacagaga cgccagatgg ttggcattcg ccagcaggat cccgcccagc
     2881 gcggcaatta acaccaacag gtagaactca tccttgttgt cgttatagcc ttcaagccac
     2941 gggtaggcga aagtacaggt ggcgaggctc gccaacaata ccagcccggt gtaaagcatg
     3001 gcgaaaccat caacgcgcat cagcggcgta acgtccatag cgcccgcctg gccgacaaac
     3061 cagagcgaaa ccagcgccgc gttaagccca ataaccgaga gcgtagcgtt gaggaaatga
     3121 ttgcgtcgcc acgcaatgga gagcatcaca accaccaccg tcaagccgac gatcagcaac
     3181 ggtagcagtg cgatcaggtt ttgtggagtt attgtcatgg cgatttacgg ccttgtagta
     3241 gtaacggaat taacaaacca ctgctggata ttgccaatcg cggagtgcga ggtatccaga
     3301 atcggctgcg gatagaagcc cagcagtacc agcagcacca ccagcaacag gatcataaac
     3361 agctcacgca gcgacatccc tggcagttcc tggctggcaa tctggctttt cgctttaccg
     3421 aagtaagcgc gatgtaacat cgccagcgaa taaacagatg caaagaccag cccaaaggta
     3481 gagataacgg taatcaccgg gacaacctgg aagctgccga acagaatcat aaattcgccg
     3541 acgaagttac cggtgccagg catcccaagc gttgccaccg caaagaacag cgacagtgct
     3601 ggcagccatt tcatcttgct ccacagaccg cccatcatgc gcatgtcgcg ggtatggata
     3661 cgttcataaa gctgaccaca aagaataaac agacccgccg ccgacaagcc gtgcgcaatc
     3721 atctggatta ccgcgccctg gtaggccaac tggctgccgg tgtagatggc aatcagcacg
     3781 aagcccatgt gggaaaccga ggtgtaggcg atcagacgtt tgatgtcggt ctgggcgaag
     3841 gccatccacg caccgtagaa gatgccgata acacccagcc acatagcgat tggcgcaaac
     3901 tctgccgacg cgttcgggaa cagcggcagg gagaaacgca gcaaaccgta agcggcagtt
     3961 ttcagcaaga tccccgcgag gtcaacggaa ccggcggtcg gagcctggga gtgcgcatcc
     4021 ggcagccagc catgcagcgg aaccaccggc attttgactg cgaaggcgat gaagaagccc
     4081 agcattaaca ggtattccac accactggac attggcgtat tcagcagctc ttcatagttg
     4141 aaggtccaga cgccggtcgc attgtagtga acaaaaacca gcgccaggat ggcgatcaac
     4201 atcaccagac cactcgcctg ggtgtaaatg aagaacttgg ttgccgccgt gatacgcgtt
     4261 ttaccgtcag aggctttatg cccccacagt gcgatcagga agtacatcgg caccagcatc
     4321 atttcccaga agaagaagaa caggaacatg tcgatggcaa ggaacacgcc gataacgccg
     4381 cccaggatcc acatcaggtt gaggtggaag aagccctgat atttttcgat ctctttccac
     4441 gaacagagta ccgccagcac accgagcaga ccggtcagca cgaccatcag cagcgacagc
     4501 ccgtcaatgg cgagatgaat agagatacca aaacgcggga tccacggcat gtcgaattca
     4561 gactgccact gcggaattcc ggcggattgc gtcagtgaat aaccgccctg caaccacagt
     4621 tgcagcgaca gcgccagcgt caatcccatg gtgatcagcg cgatccagcg cggcaccttg
     4681 acgccaaagc gttcggtctg ccagcacagg aagccgccga taaagggaat taatattagc
     4741 cagggtagta acatggcgat ctttattcct tgtaaaagtc ccgtcaggac cggattttca
     4801 acgaattctc acgacagaaa attctcttcg gactgggggt agtgtcggat gcaccgcgaa
     4861 tgcggcttat ccgacctacg ttcttatatg ccaaggggca atcccacaat ccttaactca
     4921 acgcagtacc atcaacagtg ccagcaccac gaccgcaccg atgctcatgg atgccacata
     4981 ccagcgcaga tagccgttct cacttaacag cagaccttta cctgcaaagc gggaaaggac
     5041 agccgggatg ttcatcattg agttcagcgg atcgcgtttc agcaaccagg caatacccag
     5101 gaatggcttg acgaacactt tgtcgtacag ccagtcaaag ccccaggcgt tgtaccacca
     5161 ggtgcccagc agacggcccg gcgcactgtt ggcgatggag gtcaccagag tacgtttacc
     5221 cagccacagc caggctgcca gcagaatgcc gaccaccgcg accacgccag aggtaatttc
     5281 cagggtcaac atgctgccgt gcgccagttc cgtcgtttgc ggaagcacgc cctgcagcgg
     5341 cggtacaatc agtgcgccaa cgaaggtgga aaggatcagc agcacaatca gcggcaggct
     5401 gtgagttacc cctttcacgg cgtgagcgtg aatttgttct tttccgtgga agacgatgaa
     5461 aatcatacgg aaggtgtaga gcgaggtcat aaacgcaccc accagacctg ccaccatcag
     5521 attgatatga ccattcgcca tcgcacccgc gaggatctca tccttactga agaagcccgc
     5581 agtgaccagc ggcagtgccg acagtgctgc gccgcccacc aggaagcaga gataaaccag
     5641 cggaatagat ttacgcagac cgcccatctt gaagatgttc tgttcgtgat ggcaggccag
     5701 aatgacggaa ccggatgcca ggaacagcag cgctttaaag aacgcgtgag tcatcaagtg
     5761 gaaaatcgcc gcatcccatg cctgcacgcc aagcgcgagg aacatgtagc caatctggct
     5821 catggtagag taagcgagaa cacgtttgat gtcggtctgt accagcgcgg caaaaccggc
     5881 cagcagcagc gtaaccgccc caacaatgcc caccagatgc agaacttccg gggtcatcag
     5941 gaacaggccg tgggtacggg cgatcaggta gacacccgcg gttaccatcg ttgcggcgtg
     6001 gatcagcgcg gagacaggcg tcgggcccgc catcgcgtca gcaagccatg tctgcaacgg
     6061 caactgcgca gatttaccga ccgcaccgcc cagcagcatc agcgtcgccc acatcagcat
     6121 gttattgcca tcagcaaagt gcgctggtgc cagttccacc atttcgcgga agttcagggt
     6181 gcccagttcg ttgtaaagaa tgaacagtgc gaaagcgagg aaaacgtcac ccacacgggt
     6241 cacgacgaac gctttcattg ccgctgcgcc attcttcgga tcggtgtaat agaaaccgat
     6301 cagcagatag gagcacaggc ccacgccttc ccagccgagg tacatcagca gcaggttgtc
     6361 ggcaagcacc agaactacca tgctggcgat gaacaggttg gtgtaggcga agaagcgaga
     6421 gtagccctct tcaccgcgca tgtaccagga ggcgtacatg tggatcagga aacccacacc
     6481 agtgaccact gagagcatgg tcagcgacag gccgtccaac accaggttaa aaccgatgtt
     6541 aaagtcgcct accgacatcc acgtccacag cggctggctg tatgcctgct cgccgttagc
     6601 gaagaaatca acgccgataa aggcggttac cagcgccgcc aggcccacag agccaacgcc
     6661 gacgatcgcc gaaacgtttt cagaccagcg cccacgggag aacgccagca ggacgaagcc
     6721 aatcaatggc aaaataatgg ttaaggcaag catgttcatc cgcgcatctc acttactgaa
     6781 tcgatgttca ggttctggcg acgacggtga agttgcagca gcagcgcaag gccgatactc
     6841 gcttctgccg ccgcgaggct gatggcgaga atgtacatca cctgaccgtc ggtctgaccc
     6901 cagtagcttc cggcgaccac aaaggccagc gcggaggcgt taatcatgat ttccagacca
     6961 atcagcataa acagcagatt gcgacggata accagaccgg ttaagccaag aacgaataag
     7021 attgccgcga ggatcagtcc atgttgtaag gggatcatgc gtgctcctcc gtttttcttt
     7081 tcgcgctgtc gtctttacga ttgctcagca cttcacccgc acgctcttca cgaccgacgt
     7141 ggaaggccac aaccagaccc gcgagcagca gcatagaagc cagttccacc gccagtacgt
     7201 aaggcccgaa cagcgtaata cccactgctt tagcactgat tggcgtaccg tcgataccct
     7261 gatcgttaac accgaggatg gcgtaaacaa tcaccaccag catgatggcc gacaaaattg
     7321 ccggaccaat ccacacctgc ggtttcagcc actggcgttc ctgttcgatt tctgaaccgc
     7381 ccaggttgag catcatcacc acgaacacga acagcaccat aatggcaccc gcgtagacga
     7441 taatttccag cgcaccggcg aagtaagcgc ctagtgagaa gaacaccccg gaaatcgcca
     7501 gcagcgaaat aatcaggtac agcagtgcgt gtaccggatt ggtatgggtg atcactcgca
     7561 aggtcgcaag tatggctatc aggccacaga tataaaaagc gaactccatt gcccctctcc
     7621 ttacggtaac aggctcttga cgtcgatagg cttggcttcg ttctctgctt cgcccttatc
     7681 tttgccgtcg attgccatac ctgccatccg gtagaagtta tattccgggt atttgcccgg
     7741 accggagatc agcagatcct ctttctcgta aaccagatcc tggcgcttgt attcccccat
     7801 ttcgaaatcc ggggttaact gaatcgccgt ggtcggacag gcttcttcgc acagaccaca
     7861 gaaaatgcag cgtgagaagt tgatacggaa aaattccgga taccagcgac cgtctttggt
     7921 ttctgccttt tgcagcgaga tacagccgac cgggcaggct accgcacaga ggttacaggc
     7981 tacgcaacgc tcttcgccgt ccgggtcgcg ggtcagaacg atacgaccac gataacgggg
     8041 cggcagatag accggctctt ccgggtacat tcgcgtttcg cgttttgcga acgcgtgcag
     8101 gccgatcatc cagatactac gaacctgggt gccgaaacct actaacaatt cttttaaggt
     8161 catggtctta ttgcccctta ttgcgcctgc cagagaatga cagccgccgt taccagcaag
     8221 ttgatcagcg tcagcggcag gcagattttc cagccgaagg acattacctg gtcataacgc
     8281 ggacgcggta acgacgcacg aatcaaaatg aacatcatca taaagaacgc ggttttcagc
     8341 gcgaaccaga tgaatggcgg taacaacggg ccttgccagc caccgaagaa cagcgtcacc
     8401 atcaatgcag agatggtcac aatcccgatg tactcaccca cgaagaacag accgaacttc
     8461 ataccggaat attcaatgtg gtaaccatcc gccagttcct gctcggcttc cggctggtca
     8521 aacgggtgac ggtgacacac cgccacgccc gcgatggcaa aggtaataaa accaaagaat
     8581 tgcgggatga cgttccacac atgcgcctgg ctgttgacga tgtcggtcat attgaatgaa
     8641 ccggcctgcg ccaccacgcc catcagggaa agcccgagga acacttcgta gctcagggtc
     8701 tgcgcagaag cacgcatcgc accgagcagc gagtatttgt tgttacttga ccagcccgca
     8761 aacagcaccg cgtaaactgc cagacctgcc atcatcagga agaacaaaat cccgatgttc
     8821 aggtcggcaa ccacccaacc cggactgact ggcacaattg caaaggccag cagcagcgag
     8881 gtaaaggcaa tcatcggtgc cagggtaaag atgacgcgat ccgagaactt cgggatccag
     8941 tcttctttaa agaacatttt gatcatatcc gcaaccaact ggagcgaacc gccccagcca
     9001 acacggttag gtccgtaacg gttctggaac agacccagca ggcgacgttc gccaaagctc
     9061 atgaatgccc cgcaggtgac aaccaccagc aggatcacca ccgctttgag gatggtcagc
     9121 aggatctcaa tcagttccgg tgatatccaa ctcattgttg tgcctccttg agatcctcaa
     9181 gatgcgcgcc agccagcacc ggagcaatgc cggacatacc catcggcaag cccacctgcc
     9241 ctgccgtcag cccttcggcg atttcaaccg gcagcgtgac cgtgttgcca tcgtaactaa
     9301 aggagacgcg tgtacctgcg tttacaccca acttcgcggc atccgctggg ttgagtttga
     9361 tgtacggctg cggcatacga ctctggaaga ccggagcacg ctgtgacaat tcatcactgc
     9421 caaacaggtg gtagtacggc gcaatacgcc atttcccgtc ctgcggctgg aagcgtgccg
     9481 gtacgctggt gaagtaatcc agaccatttt cgctggtttc aaacagacgc acgcccggat
     9541 cgccaaagcg cagtttgccg cccacttcgt cctggaattt gttccacgcc tgcggggagt
     9601 tccagcccgg agcccaggca aacggcactt gcgaacggtg cgcggtcggc tggttgttac
     9661 cttccatcga gaaggtgaac atggtgtcaa tatcctgcgg ctgacgcggc tcatgaacgc
     9721 tgatattggc gcgcatggcg gtacggccgc tgtaacggtg cggttcacgg gccagtttct
     9781 gcccacgaat acggaatgtc gcatccggcg cagcatcttt gatacctgcc agttccggga
     9841 ttttcgccac aacagcgtca atcacatggt cgagctgcgt ccagtccact tcacggctca
     9901 gcagggtgct gtgcagcgag tgtaaccaac gccagctttc cagcatgaca gttttgctat
     9961 cgtaataagc cggatcgtaa acctggaaga aacgttgggc gcgaccttca ttattaatta
    10021 ccgtaccgtc gctttcagca aagctggcag cggaaagcac cagatgggcg ttttccatga
    10081 tcgctgtgcg ttgatgatca accaccatca ccagcggcgc tttagccagc gcagcattca
    10141 cgcgggtagc ggaagcgtga cgatgcagat cgttttccag caccaccacc gcgtcggcgc
    10201 gtccggtttc cagttcggtc aacgcttctt caagcgaacc gccacccata atgcccagcc
    10261 ccatgctgtt gacggaacgg gcaatcatgg tgataccaac gtcagcgccg cgacctttca
    10321 gggctttcgc gacgttagcc gcagcctgaa tcacctctaa gctaccggcg ttcgtcccgg
    10381 agataatcaa cggtttcttc gcacctgcca gtgcctgcac gatgacgtcg attttgcttt
    10441 gcagctcagg ttcgataccg tcaaccgctg gtgcagagtt atccagcgca tgggcaatgg
    10501 caaaacctaa acgcgcctga tcttcaaccg gtgcgcggta agtccacgcc gcgatatcat
    10561 ccagacgagt gtcatcaacg ttggtaacaa acagcggatg cttagcacgt tgaccgatgt
    10621 tgaggattgc cgcaatctgc cagtcagcca ctttctgtgc tgccgccatt tcgcgcgctt
    10681 tacctttcac cgcctgacgc actgccagcg cgacgcgcgc gccggtctgg gtaacgtctt
    10741 cgcccagcac cagtaccgca tcgtaagatt cgatttcgcg cagagccgga gtataaatgc
    10801 cgccttcacg cagcactttc agcgccagtt gcagacgttc ctgctcaccg tgagcgatac
    10861 cggtgtagaa gttttcttcg cccaccagtt cacgcagcgc aaagttgctt tccacgctgg
    10921 cacgcggaga accaataccg atcactttct tcgactgacg cagaatatct gccgcgccct
    10981 gcattgcctg ttcggcgttg agggtaatga aatcatcgcc acgacgctgt actggctgac
    11041 gcggacgatc cttcaggttg acgtaaccgt aaccgaaacg accacggtcg cagaggaagt
    11101 agtggtttac cgtaccgttg taacggtttt cgatacgacg cagttcgccg taacgttcac
    11161 cggggctgat gttacagccg atggaacatt gctggcagat gctcggcgca aactgcatat
    11221 cccatttacg gttgtaacgc tcggagtgcg ttttgtcggt aaatacgccg gtcgggcaaa
    11281 tttcgaccag gttaccggaa aattcgcttt ccagcgtgcc gtcttccggg cgaccgaagt
    11341 agacgttgtc gtgcgcaccg taaacgccca gatctgtacc gtcagcgtaa tctttgtagt
    11401 aacgcacaca gcggtagcag gcgatgcagc ggttcatttc gtgagagatg aatggcccca
    11461 aatcctgatt acggtgggta cgtttggtga aacggtagcg acggaagctg tgtccggtca
    11521 tcacggtcat atcctgaaga tggcagttac cgccttcttc acataccgga cagtcgtgcg
    11581 ggtggttggt cattaaccac tcgaccacac tttcacggaa ctgtttcgct tcttcgtcgt
    11641 caatggaaat aaaggtgcca tcggaagccg gtgtcataca ggacatcacc aggcgaccac
    11701 gcgtgtcttc cgcgttttgg tattgcttca ccgcacactg gcggcaagca ccgacgcttc
    11761 ccagcgccgg atgccagcaa aagtaaggaa tatcaaggcc cagagacaga caagcttcca
    11821 gcaggttgtc cgctccgttg acctcgtatt ctttgccgtc tacatgaatt gtagccatta
    11881 gcatgcttcc agttttctcg gtcagggacc gagcgttaat cgaaattcgg ttaccagcgc
    11941 tctttcagca ggttcggctg aatcccatta atcaaatggg tattgctgaa cggctgtttg
    12001 attcccgcct caaattcttc gcggaaatat ttgatggcgc tctgtaacgg ctccactgca
    12061 ccaggtgcgt gggcacagaa agttttaccc gggcctaaga atcgacacag ttgctcaagt
    12121 gtttcgatat ctcccggctg accttcgcca cgctccagcg cacgcagaat tttcacgctc
    12181 cacggcagac cgtcgcggca cggcgtacac cagccgcagg actcacgggc gaaaaactct
    12241 tccagattac gcaccagcga caccatgttg atctcatggt caaccgccat cgccagcgcc
    12301 gtacccagac ggcttcccgc tttaccgata ctttcgaatt ccatcggcag gtcaaggtgc
    12361 gcttcagtca ggaaatcagt ccccgcgccg cctggctgcc aggctttgaa tttcagaccg
    12421 tcacgcatac caccggcgta atcttcaagg atttcacgcg cggtagtacc gaacggcagt
    12481 tcccacaggc ccggattttt cacccgacca gagaagccca tcagcttggt gccagcatct
    12541 ttacttttcg agatgttctg ataccactcc acgccgttag cgaggatcgc cggaacgtta
    12601 cacagggttt cgacgttgtt gacgcaggtt ggtttacccc atgcaccgga ggttgccggg
    12661 aaaggtggct tcgagcgtgg gttagcgcga cgcccttcca gggagttgat taacgctgtt
    12721 tcttccccgc agatgtagcg ccctgccccg gtatggacga acagttcgaa gtcaaaacct
    12781 gttcccataa tatttttgcc aagcaaacct gcttcggtgg cttcggcaat ggcacggcgc
    12841 agattcactg ccgcttcgat atattcgcca cgcaggaaga tgtagccacg gtaagctttc
    12901 agcgcaaacg cggagataag cataccttcc accagcaggt gcggcagttg ctccatcaga
    12961 aggcggtctt tataggtgcc cggctccatt tcatcggcgt tacacagcag gtaacggatg
    13021 ttcatggatt cgtctttcgg catcaggctc catttcaggc cggtagaaaa gcccgcgccg
    13081 ccgcgccctt tcagaccagc gtcttttacc tgattaacga tttcgtccgg agacagcccg
    13141 gtcagcgcct tacgcgcccc ttcgtaaccg tttttgctgc gatattcgtc cagccacact
    13201 ggctgtttgt catcgcgcag acgccaggtc agcggatgcg tttcgggagt acggataatg
    13261 tttttcattt ataccgctcc agcagttcag ggatcgcttc cggggtcaga tgcgcgtgag
    13321 tgtcctcatc gatcatcatg tttggccctt tatcacagtt ccccaggcag caagttggca
    13381 gcagcgtaaa gcgaccgtca aatgtcgttt gccctggttt gatgtttagc tttttctcga
    13441 gcgccgcctg aataccctgg taaccgttga tatgacagac cacgctgtcg caataacgga
    13501 tcacatggcg gccaaccggc tggcggaaga tctggctgta gaacgttgcc acgccttcga
    13561 cgtcgcttgc cggaataccc agcacatcgg cgatcgcgtg gatcgcgcca tccggcaccc
    13621 agccacgctg cttctgaacg attttcagcg cttcaatgga cgccgcacgc gggtcttcgt
    13681 agtggtgcat ctcgtgctca atcgcttcac gctctgccgc actcagctca aaagcctcgg
    13741 tttgtggttg ttgattctcg tgcataatta gcggtccaca tctgacataa caaaatcgat
    13801 actgcccaga taaacaatca ggtcagacac caggctgccg cggatcgccg ccggaatttg
    13861 ctgcaaatgc gcataactcg gcgtgcggat acgagtgcga taactcatgg tgctaccgtc
    13921 gctggtcagg tagtaactgt tgatcccctt cgtcgcctca atcatctgga aagattcatt
    13981 ggcaggcatc accggccccc acgacacttg caagaagtgg gtgatcaggg tttcgatatg
    14041 ttgcagcgtg cgctctttcg gcggcggcgt ggtcagcggg tgatccgctt tgaacgggcc
    14101 ttccggcatg ttgttgaggc actgctcaag aatgcgcaga ctctggcgca gctcttccac
    14161 tttcagcatt acgcgggtgt agcagtcaga aacaccacca ccaaccggga tttcaaagtc
    14221 gaagttttca tagccagaat aaggacgcgc cttacgcacg tcgaagtcga tcccggtggc
    14281 acgcaggccc gcgccggtgg tgccccactc cagcgcctct ttcgcgccat aggcggcaac
    14341 gccctgggaa cgacctttca gaatggtatt ttgcagcgct gctttctcgt aagacgccag
    14401 acgtttcggc atccagtcga ggaactcacg cagcaggcga tcccagccac gcggcaggtc
    14461 gtgcgctacg ccgccaatac ggaaccacgc cgggtgcata cggaaaccag tgattgcttc
    14521 caccagatcg taaattttct gacgatcggt aaaggcgaag aacactggcg tcattgcgcc
    14581 gacgtcctga ataaaggtcg agatatacag caggtggctg ttgatgcgga acagctcaga
    14641 aagcattacg cgaatgacgt taacgcgatc cggcacggtg atcccggcca gtttctctac
    14701 cgccagcacg taaggcattt cgttaacgca gccgccgagg tattcgatac ggtcggtata
    14761 cggaatgtag ctgtgccagg actggcgttc gcccattttc tccgcaccac ggtggtggta
    14821 gccgatgtct ggtacgcagt cgacaatctc ttcgccatcg agctgcaaaa cgatacggaa
    14881 agcaccgtgc gccgacgggt ggttcggacc gaggttgagg aacatgaagt cctcgttttc
    14941 agtaccacgc ttcatccccc actcttccgg tttgaaggtc agggcttcca tctccagatc
    15001 ctgtttggct ttggtcagct caaacggcga gaattcggta gcgcgcgccg ggtaatcttt
    15061 acgcagcggg tgacctttcc aggtttgcgg catcatgatg cggcgcaggt tcgggtgacc
    15121 gtcgaatgta atgccaaaca gatcccaggt ttcacgctca taccagttag cgttcgggaa
    15181 cagtttggtg aaggtcggta cgtgcaggtc gttttctgcc agcgccacct tcagcatgat
    15241 gtcgcggtta cgatcgatag aaatcagatg gtagaaaacg gaaaaatccg cggcaggtaa
    15301 cccttcgcgg tgtgtgcgca gacgttcgtc catgccgtgt aagtcaaaca gcatgacgta
    15361 aggtttcggc agtttcttta agaaatcgcc aacttccagt aattgttcac gcttgatcca
    15421 cacaacggga accccggtgc gagtcgcctg aacagtaaag gcatccggcc caaaacggtt
    15481 gcgcagttcg ccaattaccg gatcatcaag atgatcgcgg gtctgccagg cgggttcttg
    15541 cgcggttaag tcggtcatat tgttcaccat tgcaaatggt ccgtggtgac tgtcggcgca
    15601 gtaagcttcg cgaaatagat ttaggaataa gcgaagaaaa atccctttgc cgacaggcgc
    15661 aaattaaatc tcgtcaggtg tacgcaggtt ggttacggca atgcgttcac cgcgcttgcg
    15721 ttcgcgctct gattgcatat tggcgcgata aacgccctga tcgccaacca cccaggagag
    15781 cggacgacgt tctttgccga tagattcctg caacagcatc agtgcctgca tgtacgcttc
    15841 aggacgcggc gggcagcccg ggatatacac atcaaccggg atgaatttat cgacgccctg
    15901 cacaacggaa taaatatcgt acataccacc agagttggca caggcaccca ttgagataac
    15961 ccattttggt tccagcatct ggtcatacag acgctgaata accggtgcca ttttggtaaa
    16021 gcaggttcct gcaaccacca tcaggtcagc ctgacgcggg gaagcacgca atacttctgc
    16081 gccaaaacgc gccacgtcat gcaccgcggt aaacgaagtc accatctcaa cgtaacagca
    16141 ggaaagaccg aagttatacg gccaaattga gtttttacga ccccagttaa ccatgtcatt
    16201 gagcttgccc ataaacacgt ttttgttaac ttcttgctcc agagggtcgg ttacgatctc
    16261 ctgcttttgc agggggtaac ggtcgttctc accgttggga tctatgcggg tgagcgtata
    16321 atccatctta atgcctcgcg gttagcgttg acgattagcg atactgttcg tttccgggtt
    16381 catacgctcg cggcgtgaac gcgcgggcgt ccagtccagc gcgccaatac gcaccagata
    16441 aaccagacct gccagtaaca caaaaataaa aattgcagct tccacaaagc ctacccagcc
    16501 gctttcgcgg atagaggttg accatgcgaa cagatacagc gcttcaacgt cgaagataac
    16561 gaagaacatg gccaccagat aaaacttggc ggacaggcgt aagcgggcgg agccgaccga
    16621 gtcgataccg gattcaaacg gcacgttttt cgacctcgcg cgtgcgcgac cgcctaaaaa
    16681 ccaaccgcct accagcatca ggcaacacag gccaatggca acgataagaa agatagcgaa
    16741 tgcccagtga tgagcgatga cttcagtgga tgttgacata ctcattgctt actcatcaaa
    16801 agtagcgcca gattcactgc tcttcacggc agatggacgc cacatcgatt catggggagg
    16861 aataaaaaaa accttacaat cactgtagaa attcttttat acagctaatt gatgtggtct
    16921 tttactcctt tctataacct tttgtcaact ttaacaaaag tttcttcaca ttagtttaca
    16981 taatatcaac accattagca tttaatgccc tttcacccca gatccttgac gactccagga
    17041 taattagatg ttgttgaatc gtgtccgttg tgaagcaatg gaaaaaatac gggtctattt
    17101 tgacaggaat ttgtgtcgat tcctcccccc aaaagagagt attttcttga tctgtgacac
    17161 gcttttgtca ttccataaca aaaacgcagc aacaaattta cgtatttttt aacatcattg
    17221 tagcaggtga tttttttcag gcgattattt gtgcgtacgg ggcgtgaatc tctggtgatt
    17281 gaaaaatgaa cagttttgta cgttctgcac gatgtgaaga aggttcttta ctaaaaaaaa
    17341 gccgctgggg tttaaaacac ccccagcggc tcgtttttta cactattgtc tcaggaatta
    17401 tctatcgtcc gtcgattact cgatatccct ttcaatcaac aatgaatcat ccccttccgg
    17461 agcagatatt gggctgtatt gccacggatt atggtagctc tccatcgcct gatagatcac
    17521 ctgagccagc tcattattac tggacgggtc atagcacagc aaatattcgg tatcgggtag
    17581 cggcggtaag ccatcgactc cactcagcac acgcaggtct ggactcatca tctcgaccgg
    17641 ccttgccgtc acgccaagac cggctttcac tgccgcacga acggccggaa gcgtcgaggc
    17701 gacataagcc agtcgccagg gaatatctgc tttattaagc gtcgccagca ccatatcgcg
    17761 aaacggactt ggatcatcca gcaatacaag agggatcggc tcaccttttt gcaatacgta
    17821 ttccgctgcg cagtaccagt gtgttggcga ggtacgcagg ttcaatgcct taaacgctga
    17881 aggacgatgg gtggttacca tcaaatccac ttcctgggat tccagcattt ctgccatata
    17941 ggcattacgt ttaacgcgga catccagcgc taatttcgga taaaccgaac tcacgcgatt
    18001 taacaggaaa ggtaagatcg tatcggcaga ttcatctgaa gcaccgatag ttaacacgcc
    18061 ctgaagatta ctgaacatta atgatgagca ggcctcatca ttaaaacgca ggattttcct
    18121 ggcgtaacca agaagttgaa tgccatgttc agttaacagt ttgttgcgac cgtgacgagc
    18181 gaacagttct ttcccaacga gttgttccag acgctgcatt tgctgactta cggcggactg
    18241 agtacgacac acagcggcag ctgcggcagc aaaagtgttc agatcggcaa cagcaacaaa
    18301 tgttctcagc agatcgaggt cgaggttaat tatcggacga tttgcactta tcatatatta
    18361 tcacttactg gcggctcata ctgagctggt taatgctgtg cacacacaaa caagcaattc
    18421 catttgtaat gtgcctccct ggcagtttca tccggaaccc ggacgaaagt aaaaatgcat
    18481 atgagttgca ctaaaaaagc gactcacatt gttccgttat aatgcctgaa gtagatcaca
    18541 gaatatatct tcagggatcg catatctatt aagttactca ctcttttcta tttatgacat
    18601 gcgcgtgttt gtataaatgt aaatgtaagt ccttgttcca ctctcgtgca gcatcgctgg
    18661 tcatacgcga acacgtacaa acagcaatgg tgaggcggca tcaagagcag ggatccgtca
    18721 tttatgcgag cattttaccc caaaaacctt ttatttataa gggtcattgc gaattatctg
    18781 atgcaaagtt atgttatgtt aggcaaagta atcttctatt attaataagc acatcaaaac
    18841 ctttttgaat attaaataat aattaattag catcatcctc attcattaat tccgcttaac
    18901 aatagtttca caccttgccc ccattgcgac acctcggaaa tcatcacgct gttaaactct
    18961 ccgtaatgcg gaaatatcat catcgcgttt cattagtgaa ttcttaaatg aggcattttc
    19021 acacaattat cttacagata aaaaaaccag acttacaatt aagaatcaga acaattcact
    19081 atataacatt gcatgtaaag catatacacc tcattatttt gtcattatta agttattaac
    19141 agcacaatcg agccttccac tctggcaaaa tcttattctg cagaccttca aaacaccgtc
    19201 ctgggggagt acattgttct aagctgactt ccacggcagg gagtggcgat aacagcaaaa
    19261 aaggtcaaga ttcatgtccc ccattgaaaa atccagcaaa ttagagaatg tctgttatga
    19321 catccgtggt ccggtgctga aagaagcaaa acgcctggaa gaagaaggta acaaggtact
    19381 gaaactgaac atcggcaacc cagccccgtt cggttttgac gcgccagatg aaatcctcgt
    19441 tgacgtgata cgcaacctgc ctaccgctca agggtattgc gattccaaag ggctttactc
    19501 cgcgcgtaaa gccatcatgc agcactacca ggctcgtggc atgcgtgatg ttaccgtgga
    19561 agatatttac atcggcaatg gtgtatcgga gcttatcgtt caggcaatgc aggcattgct
    19621 gaacagcggg gacgaaatgt tggttcctgc accagattac ccactatgga ccgcggcggt
    19681 ttcgctttcc agcggtaaag cggtgcatta tctttgcgat gaatcctctg actggttccc
    19741 ggacctcgat gatattcgcg ctaaaattac gcctcgtacg cgtgggatcg ttattatcaa
    19801 cccaaataac ccaaccggcg cggtatattc caaagagctt ttaatggaga ttgtggagat
    19861 tgcacgtcag cataatctca ttatcttcgc cgatgaaatt tatgacaaaa ttctctacga
    19921 cgacgctgag catcactcaa ttgcgccgct ggcacctgac ctgctgacca ttacctttaa
    19981 cggactgtcg aaaacgtacc gcgttgcagg cttccgtcag gggtggatgg tgttgaacgg
    20041 gccgaaaaaa cacgccaaag gctacatcga aggtctggaa atgctggctt caatgcgcct
    20101 gtgtgctaac gttcctgcgc aacacgccat tcagaccgcg ctgggtggtt atcagagcat
    20161 cagtgaattt attacccctg gcggtcgtct ttatgagcag cgtaaccgcg cgtgggaact
    20221 gatcaacgat attccgggcg tttcctgcgt gaaacctcgt ggtgcgctgt atatgttccc
    20281 gaaaatcgac gccaaacgct ttaacattca cgacgatcag aaaatggtgc tggatttcct
    20341 gttgcaggaa aaagtcctgt tggtgcaagg gacggcattc aactggccgt ggccggatca
    20401 cttccgcatt gtcactctgc cgcgtgtcga tgatatcgag ctgtctttga gtaagttcgc
    20461 gcgtttcctt tctggttatc atcagctgta atcttaattt cactgccgga gattgcatcc
    20521 ggcagtgtta tcccgccaca atgacctgat gatgtcatca tacgtaaggt cactatgaaa
    20581 cagagccatt tttttgccca tctctcacgc ctgaaactca ttaaccgctg gccgctaatg
    20641 cgcaacgtgc ggacggaaaa tgtgtccgaa cacagtttgc aggtagcgat ggtcgcccat
    20701 gcgctggcag ctatcaaaaa tcgtaaattt ggcggtaatg tcaacgccga acgtatcgct
    20761 ttactggcga tgtaccacga tgcctcagaa gtgctcaccg gcgatctccc tactccggtg
    20821 aaatacttca attcgcaaat cgctcaggag tacaaggcta ttgaaaaaat cgctcagcaa
    20881 aaactggtcg atatggttcc ggaagagctg caggatatct ttgcgccgtt aattgacgag
    20941 catgcatata gcgatgaaga aaaatcgttg gtgaaacagg cagatgcact gtgtgcatat
    21001 ctgaaatgtc tggaagaact cgcggccgga aataatgaat tcttgctggc aaaaacgcga
    21061 ctggaagcga cgcttgaagc gcgtcgcagc caggagatgg actacttcat ggaagtattt
    21121 gttcccagct tccatctttc gctcgatgag attagccagg attcaccgct gtaagcagcc
    21181 ggagtctgcg tcgcatcagg caataagcgc cggatgcgac atcaggctct tgtcaaaacg
    21241 gaaacagcat cgggatcatc accacacaaa ccgccatcac gataatggtg aacggtaccc
    21301 ccaacttcac aaagtcactg aagctgtaat ttcccggacc taaaaccagt gtgttaaccg
    21361 gtgaagaaac cggtgtcata aaggcggcag atgctgccat cgccacgacc atcgcgaatg
    21421 gataaggcga cacccccatc gttttggcag cagccagcgc aatcggagcc atcaacaccg
    21481 ccgtcgcggt attagagata aacagcccaa taaccgccga caaaacaaac aaacacccca
    21541 gcatcatatg tggcccgtaa ccgccgccaa tgtccatcag ccctttcacc gccagcgcga
    21601 cacctcccgt tttctgtaat gccacagcaa acggcatcat cccaacgatc aaaataatgc
    21661 tcggccagtg aatggattta taggcgcttt cggcatcgat acagcggaat ttccccatca
    21721 gcaggcaggc gatgatagcg gcaacaggat taggaatttc atcggtcagc attaacgcca
    21781 ccattagcac cagacagaaa atggcatggg gtgcctggct gtgcgcgggc gatgcttcac
    21841 tcacctcttc cggtaagttc agcgctacga agtcgcggcc ctgttttgcc agcataccga
    21901 tcagtttcca gttaccaaca accaggatga tatcgcccag cagcagaggc tcatccgcca
    21961 gcgaaccttc cagcgccacg ccattgcgct ttagccccac cacattcagt ccgtagcggg
    22021 tacgaaaacc aatttcgcgc accgatttac caatcagttc tgactcagga attaatgaaa
    22081 tctctgccat gcccacatca agggcctggt cagaaaaata ctcgccgcgc agtaccatcg
    22141 gctccagcaa ttgctcacta caaaattgcc ggagatcgac atcagccgca gacatatcaa
    22201 taagcaaaac gtcacgcgcg cgaaattcag aaaccccatt aacgttcacg ataacgcgac
    22261 gaaaacgccg ccagcgttca acaccgatga cgttagcgcc ataacgctca cgtaatttga
    22321 gatcgtccag ccgttgacca atcattggcg atccggggcg aatagccaga cgtcgcgcac
    22381 gcccggtcag tcgatattca cggataagat cgcgaaaggt tcgacgcgtc cagccttcgc
    22441 gctgcggggt ctgggtatcc cctttcagca tgaaacgcat cactaacata tacaaaatac
    22501 ccagcaccag cacgaccagg ccaataggtg ttacgctaaa gaaactgaag ccgtgatagc
    22561 cttcacgcag caattcactg ttgactacca ggttcggcgg cgtcgccacc agcgtcatca
    22621 tgccgctaat cagcccggca aaacttaacg gcatcatcag acgtgacggc gaagtttgca
    22681 tacgcatggc aacgcttaac accacgggaa taaagatagc gacaacgccg gttgaactca
    22741 taaacgcgcc aagccccgcg acggtcagca tcaacaaaac caacattttg atttcactgt
    22801 tgcccgccac tttgaccagc catgttccca ttacggtggc aacaccggta cggaccaaac
    22861 catcgccaat aataaacaag gcggcaatca ggacaacgtt aggatcagaa aagccggaaa
    22921 atacttcggg gaccgtcagc gttccgctta atgcaaacgc gacaataaca aacaaagcga
    22981 ccgcatccat acgcactctg cccgtcgcaa acaagacgat ggcaacggcc agtaatgaaa
    23041 gaacccaaat caattcaccg ttcacaactt atccttgtta attgaggggg atgacttgat
    23101 tctgccataa aaaagccccg acgagacggg gctaaatcat gatcaggtgt ttcactgaat
    23161 aataacatcg ccatttggct gtttggtcac agtaatttgc tccagactgt ggaggaccaa
    23221 atcgacctca ttcaggcgcg gggtatctgc cggagcgtta accgcaatga catggcaacc
    23281 cgccgccagg ccagaaagca cgccagcggg agcatcttcc accaccacac actcctgcgg
    23341 cgcaagcccc agcagctgcg cacctaacag atacgcatca ggttctggtt ttccgcgctt
    23401 cactcgctca gcggttacaa acacctctgg tgcgggaagc ccagctattt tatggcgcgc
    23461 tcgcgctacc ggcatggagc cagaagtcac aatggcccac ggaatacctg ctttattcaa
    23521 atgattgagt aaggcgattg cccccggaag cgcggtaata ccttcggttt ccgtggcctc
    23581 gatgtgctcc agacgcgtaa actcggcggc aatatcagcc tcggatttgc ccgccataaa
    23641 atggcgcaaa gaggtgatcg cctgtttacc gtgaatgaaa gccagcacct cttccggtgc
    23701 taacccatga cgtctggccc agttgctcca cgcccgttct accgcaggca gggaatccac
    23761 cagcgttcca tcaagatcaa acagaaaacc tttgcaccgc acacgggcct cctcaggcgt
    23821 tgataatttg attaatttcg ttggcgctca aatggtactg acgcgggcag gcatgccaca
    23881 cattaagcat gcgctgatat ttttcccaca ttggcgtctg ggcgttaaaa ccgtgagttc
    23941 cggcgtcaaa atgggtatag cgcccttcca cattaaccat aaagcggaca taaccgaggt
    24001 aacgtgcttc agtggcggcg tcaaagccga ggaaggtgac acgacgttca tcgatggatt
    24061 gctggtcctg caaattagac caggaaacat gcaacgcatg atacatctcc ataatgtcga
    24121 tgatagtgcg gcaggtttct tctttcagct cgccaaactc gcgatccaat tcacgcatct
    24181 gtaatccgta accacgctca ataattgttt gcaggcgacg gtaacgttca gcatttgccg
    24241 gatcgagcat agtcatcatc ttgtactgat tagacaaaat aagacgttgc gcgttggtca
    24301 tttccattgt tgactcctgt atcactatac tacggtgaaa aaaaagaagg ctgagtatgc
    24361 cttcttttat atgcgtaatc aggggtcaat tacaaatcat caaggaaagt tttatccagt
    24421 tgtttgaagg cgcgcttaag cgtgtcagct aatgcctggt aatcaggctt gccttcaacg
    24481 ggtgccaaca cctgtccaga ctcctgcaat ttaccgcgaa cttcataaaa ccagttaagg
    24541 attgcagggg gtaatggcgt tacagaacgc ttgcccagcc accacaatcc ctgcatgggt
    24601 aaacttaagg cgaacagcgc agtggcaact gccggcccaa gctgaccgcc cagggcaatc
    24661 tgccagcaga gagtaaatac ggcgatcggc ggcataaaac ggatcgcata acgcgtcatc
    24721 ttgataacgc gattttcgac aaagaccggg gcaaggcgtt tttccagcgg ccacgtcttt
    24781 gagtaatgct gtccccggcg aaacaagcta aaaaaattaa cagaacgatt atccggcgtt
    24841 gacatgcttc acctcaactt cacatataaa gattcaaaaa tttgtgcaaa ttcacaactc
    24901 agcgggacaa cgttcaaaac attttgtctt ccatacccac tatcaggtat cctttagcag
    24961 cctgaaggcc taagtagtac atattcattg agtcgtcaaa ttcatataca ttatgccatt
    25021 ggctgaaaat tacgcaaaat ggcatagact caagatattt cttccatcat gcaaaaaaaa
    25081 tttgcagtgc atgatgttaa tcataaatgt cggtgtcatc atgcgctacg ctctatggct
    25141 ccctgacgtt tttttagcca cgtatcaatt ataggtactt ccatgtcgag taagttagta
    25201 ctggttctga actgcggtag ttcttcactg aaatttgcca tcatcgatgc agtaaatggt
    25261 gaagagtacc tttctggttt agccgaatgt ttccacctgc ccgaagcacg tatcaaatgg
    25321 aaaatggacg gcaataaaca ggaagcggct ttaggtgcag gcgccgctca cagcgaagcg
    25381 ctcaacttta tcgttaatac tattctggca caaaaaccag aactgtctgc gcagctgact
    25441 gctatcggtc accgtatcgt acacggcggc gaaaagtata ccagctccgt agtgatcgat
    25501 gagtctgtta ttcagggtat caaagatgca gcttcttttg caccgctgca caacccggct
    25561 cacctgatcg gtatcgaaga agctctgaaa tctttcccac agctgaaaga caaaaacgtt
    25621 gctgtatttg acaccgcgtt ccaccagact atgccggaag agtcttacct ctacgccctg
    25681 ccgtacaacc tgtacaaaga gcacggcatc cgtcgttacg gcgcgcacgg caccagccac
    25741 ttctatgtaa cccaggaagc ggcaaaaatg ctgaacaaac cggtagaaga actgaacatc
    25801 atcacctgcc acctgggcaa cggtggttcc gtttctgcta tccgcaacgg taaatgcgtt
    25861 gacacctcta tgggcctgac cccgctggaa ggtctggtca tgggtacccg ttctggtgat
    25921 atcgatccgg cgatcatctt ccacctgcac gacaccctgg gcatgagcgt tgacgcaatc
    25981 aacaaactgc tgaccaaaga gtctggcctg ctgggtctga ccgaagtgac cagcgactgc
    26041 cgctatgttg aagacaacta cgcgacgaaa gaagacgcga agcgcgcaat ggacgtttac
    26101 tgccaccgcc tggcgaaata catcggtgcc tacactgcgc tgatggatgg tcgtctggac
    26161 gctgttgtat tcactggtgg tatcggtgaa aatgccgcga tggttcgtga actgtctctg
    26221 ggcaaactgg gcgtgctggg ctttgaagtt gatcatgaac gcaacctggc tgcacgtttc
    26281 ggcaaatctg gtttcatcaa caaagaaggt acccgtcctg cggtggttat cccaaccaac
    26341 gaagaactgg ttatcgcgca agacgcgagc cgcctgactg cctgatttca caccgccagc
    26401 tcagctggcg gtgctgtttt gtaacccgcc aaatcggcgg taacgaaaga ggataaaccg
    26461 tgtcccgtat tattatgctg atccctaccg gaaccagcgt cggtctgacc agcgtcagcc
    26521 ttggcgtgat ccgtgcaatg gaacgcaaag gcgttcgtct gagcgttttc aaacctatcg
    26581 ctcagccgcg taccggtggc gatgcgcccg atcagactac gactatcgtg cgtgcgaact
    26641 cttccaccac gacggccgct gaaccgctga aaatgagcta cgttgaaggt ctgctttcca
    26701 gcaatcagaa agatgtgctg atggaagaga tcgtcgcaaa ctaccacgct aacaccaaag
    26761 acgctgaagt cgttctggtt gaaggtctgg tcccgacacg taagcaccag tttgcccagt
    26821 ctctgaacta cgaaatcgct aaaacgctga atgcggaaat cgtcttcgtt atgtctcagg
    26881 gcactgacac cccggaacag ctgaaagagc gtatcgaact gacccgcaac agcttcggcg
    26941 gtgccaaaaa caccaacatc accggcgtta tcgttaacaa actgaacgca ccggttgatg
    27001 aacagggtcg tactcgcccg gatctgtccg agattttcga cgactcttcc aaagctaaag
    27061 taaacaatgt tgatccggcg aagctgcaag aatccagccc gctgccggtt ctcggcgctg
    27121 tgccgtggag ctttgacctg atcgcgactc gtgcgatcga tatggctcgc cacctgaatg
    27181 cgaccatcat caacgaaggc gacatcaata ctcgccgcgt taaatccgtc actttctgcg
    27241 cacgcagcat tccgcacatg ctggagcact tccgtgccgg ttctctgctg gtgacttccg
    27301 cagaccgtcc tgacgtgctg gtggccgctt gcctggcagc catgaacggc gtagaaatcg
    27361 gtgccctgct gctgactggc ggctacgaaa tggacgcgcg catttctaaa ctgtgcgaac
    27421 gtgctttcgc taccggcctg ccggtattta tggtgaacac caacacctgg cagacctctc
    27481 tgagcctgca gagcttcaac ctggaagttc cggttgacga tcacgagcgt atcgagaaag
    27541 ttcaggaata cgttgctaac tacatcaacg ctgactggat cgaatctctg actgccactt
    27601 ctgagcgcag ccgtcgtctg tctccgcctg cgttccgtta tcagctgact gaacttgcgc
    27661 gcaaagcggg caaacgtatc gtactgccgg aaggtgacga accgcgtacc gttaaagcag
    27721 ccgctatctg tgctgaacgt ggtatcgcaa cttgcgtact gctgggtaat ccggcagaga
    27781 tcaaccgtgt tgcagcgtct cagggtgtag aactgggtgc agggattgaa atcgttgatc
    27841 cagaagtggt tcgcgaaagc tatgttggtc gtctggtcga actgcgtaag aacaaaggca
    27901 tgaccgaaac cgttgcccgc gaacagttgg aagacaacgt ggtgctcggt acgctgatgc
    27961 tggaacagga tgaagttgat ggtctggttt ccggtgctgt tcacactacc gcaaacacca
    28021 tccgtccgcc gctgcagctg atcaaaactg caccgggcag ctccctggta tcttccgtgt
    28081 tcttcatgct gctgccggaa caggtttacg tttacggtga ctgtgcgatc aacccggatc
    28141 cgaccgctga acagctggca gaaatcgcga ttcagtccgc tgattccgct gcggccttcg
    28201 gtatcgaacc gcgcgttgct atgctctcct actccaccgg tacttctggt gcaggtagcg
    28261 acgtagaaaa agttcgcgaa gcaactcgtc tggcgcagga aaaacgtcct gacctgatga
    28321 tcgacggtcc gctgcagtac gacgctgcgg taatggctga cgttgcgaaa tccaaagcgc
    28381 cgaactctcc ggttgcaggt cgcgctaccg tgttcatctt cccggatctg aacaccggta
    28441 acaccaccta caaagcggta cagcgttctg ccgacctgat ctccatcggg ccgatgctgc
    28501 agggtatgcg caagccggtt aacgacctgt cccgtggcgc actggttgac gatatcgtct
    28561 acaccatcgc gctgactgcg attcagtctg cacagcagca gtaatctcgt catcatccgc
    28621 agctttgcgc tgcggatatc tgaaccggaa ataatcacta tttccggttt tttattctct
    28681 taatttgcat taatcctttc tgattatctt gcttaactgc gctgcatcaa tgaattgcgc
    28741 catctcactt tgcatactta ccactttgtt ttgtgcaagg gaatatttgc gctatgtccg
    28801 caatcactga atccaaacca acaagaagat gggcaatgcc cgatacgttg gtgattatct
    28861 tttttgttgc tattttaacc agccttgcca cctgggtagt tccggtgggg atgtttgaca
    28921 gtcaggaagt gcagtatcag gttgatggtc aaacaaaaac acgcaaagtc gtagatccac
    28981 actcatttcg cattctgact aacgaagcag gcgaacctga gtatcaccgc gtacagctgt
    29041 tcacgacggg cgatgaacgc ccgggcctga tgaacttccc gtttgaagga ttaacctcag
    29101 gatcgaaata cgggacagcc gttggcatca tcatgtttat gctggtgatt ggcggcgcgt
    29161 ttggcattgt gatgcgtaca ggaaccattg ataacggtat cctggcgctt attcgccata
    29221 cccgcgggaa tgaaattctc tttattcctg cgctgtttat tctgttttca cttggcggcg
    29281 cggtatttgg tatgggagaa gaggccgtcg cctttgccat tatcatcgca ccgctaatgg
    29341 tccggctggg ctatgacagt attaccaccg tcctggtgac ctatattgcc acgcaaatcg
    29401 gttttgccag ttcgtggatg aacccgtttt gtgtggtcgt tgctcagggg attgccggcg
    29461 ttccggtgct ttctggctcc gggttgcgca tcgtggtgtg ggttatcgcc actctgattg
    29521 gcctgatctt taccatggtg tacgcctcac gagtgaaaaa gaatcctctt ctgtcacgcg
    29581 tgcatgagtc cgaccgcttc tttcgtgaaa agcaggctga tgttgaacaa cgtccgttta
    29641 cctttggtga ctggctggta ttgattgtcc tgaccgccgt aatggtctgg gtgatttggg
    29701 gcgtgatcgt taatgcctgg tttattccag aaattgccag ccagttcttc accatgggtc
    29761 tggtgattgg catcatcggc gttgttttcc gccttaacgg catgacggtt aataccatgg
    29821 cttcatcctt taccgaaggg gcgcgaatga tgatcgcccc tgccctgctg gtgggtttcg
    29881 ccaaagggat tttgctgctg gtcggtaatg gtgaagcggg tgatgccagc gtgttaaata
    29941 ccatcctcaa cagcattgcc aatgccatta gcggtctgga caacgcggtc gcggcctggt
    30001 ttatgttgct cttccaggcg gtatttaatt tcttcgtgac gtccggttct ggtcaggcgg
    30061 cgttaaccat gccgttactg gcaccgcttg gcgatctggt cggtgttaac cgccaggtta
    30121 ccgtgctggc attccagttt ggtgatggct tcagtcacat catttaccca acctcagctt
    30181 cgttaatggc aactctcggt gtatgcaggg tggacttccg taactggctg aaggtgggcg
    30241 cgaccctact tggactgctg tttattatgt ccagcgtcgt agtgatcggc gctcagttga
    30301 tgggctacca ctaaaaatgt taagagccgc aattgcggct cttttttcat tctgccgttt
    30361 cagtctctac ggcttcattt ttggcattgc gcttcatcca caacgccagc gctttcagcg
    30421 agtctggagt gaactcatcg cagcgtgcgg tgatttcttc cggcgtcagc cagcaaactt
    30481 cactgacttc atcttcctgt agggcgaagg gaccgtgaga gacgcagctg aacaacgcgc
    30541 cccagacacg gcaattttta tcttcgaaat agaactgccc gtgctcggca aaggggacac
    30601 cggcaatgcc caactcttct tccgcttcgc gacgcgcgga ttccagcagt tgctcatcgg
    30661 cctgaaccac accgcctgcg gtcgcatcta acatgccggg taaaaagtct tttgtctcgg
    30721 tacgacgctg gaccagaatt ttgcccatgc catcatgcac gacgatgtaa gttgcacgat
    30781 gacgcagaca ctgtgcccgc atttgttccc ggctggcttg tgcaatgact tcgttctctt
    30841 cattgacaat atccacccat tcagtacttg ccaaacgacg ctgttccatt atcaggaaac
    30901 cttctttttc tggcgctctt acggcgcatt ttgagttgtg ggtaaattac ggattaatcg
    30961 cgacctgcgc aatgatactt tgatcattga gtgcgattac actaagtacg tcattatcca
    31021 gcatgccata actcgccgga ttaccgcctt tcggaatact caccgagccg gggttgaagt
    31081 ggaaaatctc cccccgctgt tctgccactg gcagatgggt atgaccgtac accagcacat
    31141 cgttctggtt taaagcaggt agattttccg ggccaaaaag atgaccatgc gtcaaaaaca
    31201 gacgttgttt ttccagtaat acctgttgcc acggcgcggt tatcgggaaa tgcagcagca
    31261 tttgatccac ttcgctgtcg cagttgccgc gcacagcgat aaccttatgt gccacttcat
    31321 taagccgttc agcgactttg gctggcgcgt aaccctccgg taaagcatta cgcgggccgt
    31381 gattcaacac gtcgccaagg atcaccagcc actgggcacc gctttgggca aacaactcca
    31441 gaacacgttc cgtcgccggt aacgacccat gaatgtccga tgcaaacatc agtttcatca
    31501 ctcactcctc gtcgaaaaaa cgtaagctat gatactggat tctgtcgttg ctatcagcca
    31561 gattgcttcg ccgaaagtgc aataaaacgc tggacagacg ctcgctgcca ctggaatgtc
    31621 gcataatcca ccaggcgttc tggcacctca tcgccatgta gtaccaggcg gttaatcatt
    31681 agcgccagat cagtatcagc aatgcaccat tcaccaaata aattcggctg acccagtact
    31741 aacaaatgtt ctgccatcgc aaacagtttc tctgcactgg cttttccctc ggccgttagt
    31801 ggcgcttttt tcgcccccgc aaagacaaca tccgtcggac gctcttcgcg gatgggcatc
    31861 agatcgctgc gcagccaggc ctgaatctgt cgtgcacgcg cacgattttc taaatcaagc
    31921 ggataaatac gttcccaggt cggtggcgca aatcgatctt ccagatactc cgcaatggca
    31981 gaagattcac tcaactcaaa atcatcgatt tgtaataacg gcacacggcg tgtctgaccg
    32041 taaccttgcc acgtcggctg caaatgttca ccgctgtcga ggtcgatggt cttgatatga
    32101 aacgacaggc ctttttcctg caacgccacc caggcggata acacataagg ggagaaaaag
    32161 tgggcatctg accaaagcgt gatagcgggt ttactcatta tgtcctcggc aataaagggg
    32221 gctggctatc aaactataga gcctttttgt cactgtcacg tgacgaatac tcacgtaatt
    32281 cgccgcgctt tctatacttg tggtgttcag atgattaaac aaccggagct gcaatgatcg
    32341 atctctattt cgccccgaca cccaatggtc acaaaattac gctgtttctc gaagaagcag
    32401 agcttgatta tcgcttgatt aaggtagacc tggggaaagg cggtcagttt cgtccggaat
    32461 ttttgcgcat ttcgcccaac aacaaaattc cggcaattgt tgatcattct cctgccgatg
    32521 gcggcgaacc gttaagcctc tttgagtctg gtgccatttt gttgtatctg gctgagaaaa
    32581 caggactctt tttgagtcat gaaacgcgtg agcgcgccgc cacattacag tggttattct
    32641 ggcaggtagg cggactgggg ccgatgcttg ggcaaaatca tcattttaat cacgcagccc
    32701 cccaaaccat tccttacgct attgaacgtt atcaggttga aactcagcgt ctttaccatg
    32761 tactgaacaa gcggctggaa aactcgccct ggctgggagg cgagaactac agcattgcgg
    32821 atattgcctg ctggccgtgg gttaatgcct ggactcgcca gcgaattgac ctcgcaatgt
    32881 atccggcagt caagaactgg catgagcgga tccgttcgcg ccctgccacc gggcaggcac
    32941 tgctaaaagc acaactcggt gatgagcgtt cggatagtta acagaaacag gttctcgtgt
    33001 attatttcat cctaagtaaa acaacggaga acctgcaatg gcacaacctg ccgctattat
    33061 tcgtataaag aaccttcgtt tacgtacgtt tatcggaatt aaggaagaag aaattaacaa
    33121 ccgtcaggat attgttatca atgtgacgat ccactacccc gccgataaag cgcgcactag
    33181 cgaagatatc aacgatgcgc tgaattatcg caccgtaacg aaaaacatta ttcagcatgt
    33241 agagaataac cgtttctctt tgctggaaaa attaactcag gatgtgctcg atatcgcacg
    33301 tgaacatcac tgggtgacgt atgctgaagt ggagatcgat aaactgcacg cgctgcgcta
    33361 cgccgattcg gtatccatga ccttaagctg gcagcgttaa ccgccatatc gggaggctgc
    33421 atgaacatag tgatcaccgg agggacggga ttaattggtc gccatttgat tccgcgtttg
    33481 ctggagctgg gccatcaaat cacggtagtg acgcgtaacc cacagaaagc cagttccgtt
    33541 ctcggccctc gggtgacgct atggcaaggg ctagccgatc aaagcaacct caacggcgtt
    33601 gatgcggtaa tcaacctggc cggagaaccg attgctgata aacgctggac tcacgagcaa
    33661 aaagagcgtc tctgccaaag ccgctggaat atcacgcaaa aactggtcga tttgattaat
    33721 gccagcgaca cgccgccgtc ggtactcatt tccggctcgg caacgggcta ttatggcgac
    33781 ttaggtgaag tggtggttac cgaagaggaa ccgccgcata acgaatttac ccataaactc
    33841 tgcgcccgct gggaagaaat tgcctgccgg gcgcaaagtg acaaaacgcg agtgtgcctg
    33901 ctgcgtaccg gtgtagtgct ggcaccggat ggcggtattc tcggtaaaat gctgccaccg
    33961 tttcgtcttg gcctgggcgg gccgattggt tccggtcggc agtatcttgc ctggattcat
    34021 atcgatgata tggtcaacgg cattctctgg ctgctggata acgagctgcg cgggccattt
    34081 aatatggttt cgccctaccc ggtacgcaat gaacaatttg cccatgcgct cggtcatgcg
    34141 ctgcatcgcc cggccatttt gcgcgtcccc gcgaccgcca ttcgactgtt aatgggcgaa
    34201 tcttcagtac tggtattagg tggacaacgc gcgctgccta aacggctgga agaagcgggt
    34261 tttgcgtttc gctggtacga tttagaagag gcgctggcgg atgtcgttcg ctgatgtggt
    34321 ttacagcaaa catccgccag ttaactcccg gtgttacagg attagtggct ttgcgcgata
    34381 agatcgtctg gtgaaagtcg ggtcaccatc ataactaact ctctgtctaa acctctatcc
    34441 agcatctcct gagcaatacg cagggcttct tcgtgtttgc cctgcattgc gccttcttca
    34501 cgtaatctgt cagcaatggt catcagtttc tccttttctt gtggtgcgcg ttccgctatc
    34561 tcaccaataa atgcacgaaa acgctgggca tcccctgttt gtaatacgta attaaacagg
    34621 gcttttagct gtctgtcatt agtgttccct gtaactagca gcgaaacaat ttggtcgact
    34681 aatcccaaca gatcgcgctg acgaatatgt ttctgaatta actccaacag cgccattttg
    34741 cggtgttgca taatctcgtc atccggcacc acggtaatat ccaccaacgg aaacgctgat
    34801 gaatatattt tgtgggctat agcaggctcg gcaaattcat caagccagca gagtgaataa
    34861 ggataaggac ttctgcaacc atgataaaac agcatcggga tcaccaatgg aagctcttta
    34921 tagcccgcat caagatggtt ttgcattgcc gcaatggaat aacgcatcat gcgaaaagcc
    34981 attaattctt ccggcttact ttggtgctct atcactacat aaatataacc cactccctcc
    35041 tgcgttttca cagaccacaa gaggtcggaa taatattgcc gcaggtcgtc atcaataaaa
    35101 ctgtttggtt ccagtttaag cgtcgttaaa tcacacagtt tgcgcagcgg cgcgggaaga
    35161 tgaatatcaa taaaatcccg cgcggtgtct ggatggcgta aaaaagattt aaataccgca
    35221 tcatgcggcg tggaagttgt cgatattgtc atggcgttcc gtcacccctc aaatttaaga
    35281 tgacgcgaca ataaccacga ttaacaccca atgcagcagg cagtttttat ctttggacag
    35341 cgaattcaga agtattttta gcggactgca acttttacat ttcagcggaa gctgactcgc
    35401 aaattcccca tgaaaatact ccggcagcgt tagccaccgg agaggaaatt atttcagcga
    35461 tcccttaagg aactgttgca gacgagggct ttgcgggttg ccaaataact gctccggcgc
    35521 gccctcttct tctattttcc cctgatggag gaaaatgaca tgagtagaaa catggcgagc
    35581 aaagcccatt tcgtgagtca ctaccaccat ggttttcccc tcttctgcca gttgctgcat
    35641 aatacgcaac acttcgccta ccagttcagg atcgagcgcc gaggtaggtt catcaaacag
    35701 taaaacttcc ggttccatcg ccagcgcccg cgcgatagaa acacgctgtt gctgaccgcc
    35761 ggaaagatgc accggatatt tcccctgcgc acgttcgtct atcccgactt ttgccagata
    35821 cttgaccgcc cgctcgcgcg cttcctgctt gctcaggccc aacacctgaa tcggcgcttc
    35881 catgacgttt tccagcaccg tcatatggct ccagagattg aagtgctgga ataccatcgt
    35941 caggcgtgtg cgcagtaagc gcagttgatt tttatcggcg actttgagtt gaccgtcttt
    36001 gtcgcgcacc agattgatcg tctggccatt gaccacgatc gacccttcac tcggtttttc
    36061 gaggaagtta atgcagcgca gaaaggtact tttccccgat cccgacgatc cgatgatgct
    36121 tattacatct ccggcattcg cttgcagtga gacccctttc agcacttcat gttcgccgta
    36181 gcgtttgtgc aaatcgataa cgtttaattt attctcggac atcgtattct cagtgcgttg
    36241 aagaaggttt cacatgctgc aaccagcgtt tttccgctct gcgaaagagg ctgatcagga
    36301 cataagagat gattaaatag agcaccgcgg caatgccgaa ggcggtaaaa ggttgatacg
    36361 tggcggcgtt aatatcgcgg gctattttca gcagatccgg caccgtggcc gtaaacgcca
    36421 gcgcagtaga gtgcagcatc aggatcactt cgttgctgta tgccggtaac gcaatacgca
    36481 gcgcagaagg caaaataatg caacgataca ttttaaaagt cgagaagcca taggctctgg
    36541 cggcttcaat ttccccatgc ggaaccgaac ggattgcccc agcaaaaatc tcggtagtgt
    36601 aagcgcaggt gttaagcgtc agcgccagca cggtacagtt caggccactg cggaagaaag
    36661 cgttaaggaa ttcggttccc ttaacaatct caagcgtgta catgccggaa tagaacacca
    36721 gcaactgaac atacagcggc gtaccgcgaa aaatataggt aaataaccag attggaaact
    36781 ggatgtattt attactggag acacgaccaa tcgccagaaa cagcgccagg actccgccta
    36841 tcactaccga caaaataagc agccacagag tgatcgccac accagtaaag cgataaccgt
    36901 cggtccacag cagcggtttc cagtattcat gtaagatttc gatcacaggt cagccctctt
    36961 cacacccacg gagtagcggc gctcaaggaa cagcagcaca ccattggaaa cagtggtgaa
    37021 aaccaggtaa atcacgccac agacgatggc gaaatagaac ggttcccagg tacttttgcc
    37081 tgccagttgg gtggctttga ccacatcttc caggccgagt aacgaaacca gtgcggtaga
    37141 tttgaggatc acctgccagt tgttgccaat gcctggcagg gcgtaacgca tcatcgccgg
    37201 aaacatgatc cgccgaaaca cttgcccacg agtaaaaccg aacgccgtcg ccgcctctat
    37261 atgccctttc ggcactgcca taaacgcgcc acggaacgtt tcggtaaaat aagcaccgta
    37321 gataaaaccg agagtaataa taccagcgac catcggatcg atatcaatct gcccgacgcc
    37381 catcgcctcc gtcaccgtgt ttagcgcaat ctgcaaaccg tagaaaatca gcagcatcaa
    37441 caccaagtcc ggcacgccac gaatcagcgt ggtgtaccct tcgaaaatca gccccgaaag
    37501 ccgattttgc gagagcttac cgccagcgcc aattaaaccg atgattacag cgagcactac
    37561 agaactgata gccagctcca gcgtgacgag cgcaccctgt aaaataacac ctgaaaaccc
    37621 atacaacatg ctgcctgtcc tgtcgtgtgt ggtgaattac cgcctcttgt ctccctccgg
    37681 ttacccgaag ggagcgggct ttctttcacc gatggcgatt aaccgccata aacatcaaaa
    37741 tcgaagtact ttttcgctaa tttctcgtaa gtaccgtcag cgcgcatttc ggcaaaggct
    37801 ttgttcagtg cctcgcgcag ttcgttatct tctttacgca ggcccatgcc ggtccctacg
    37861 ccaaacagtt tttcatcttt aacagacggg ccaccgaatt tgtaatcttt accgacgggt
    37921 tgtttgagga aaccttcact ggcagcgacc tcatcctgga acgcggcatc aatacgtccg
    37981 gcagtcaggt cagaataaat gttgtcctgc ccctgatacg agacgatttc aatgcctttt
    38041 ggtgcccaat gttcattacc gaacgtctcc tgggtggtgc cctgcaatac gcctacccgt
    38101 ttgcctttca gcgactcgac tgtcggctga atgtcagaat ttttcgccac caccaaacga
    38161 gaatcggcag cgtacagttt gtcggtgaag gctatttctt gctgacgttt ttccgtaatg
    38221 gaaagcgatg acatgatggc gtcaatcttc ttcgctttta aggacgggat taacgcatcc
    38281 agcggatttt cgacaaacgt acattgcgta ttgatgcgtt tgcataattc ctttgccaga
    38341 tcgatatcga agccaaccag ttcgccttgt gaattttttg attcaaatgg cgcataggtc
    38401 gggtcggtac cgatgcggat gttttgcgga atcgcagcaa acgccgcagt tgcgctggag
    38461 aaggccagaa ccagagagag cgatagcacc agttttttca taatgtcctc aactgacagt
    38521 ctttttatag ggaatattta caggtttgtt acacttatcg tgccataaaa ttgaccatca
    38581 aggcaaaata tcccgccccg ttagacgtat tatttttcat taaaaatgct taagtatgca
    38641 tttcaatgca ccacgatagt gcaacaaacc tggcgtgcac catgatgatc attccatcag
    38701 gtacagcttc ccagcgacgt atcagtcacc gtagacatta aagtcgaaat actttttcgc
    38761 catcttgtcg taggtgccgt cctgacgcag ctcgccaagc gccttattga aggcagccgt
    38821 cagttcagca tcatctttac gtagccctac accggtgcca tcaccgaagt attttttgtc
    38881 ttttactgat gagccagcaa aggcgaaatc tttaccagca ggttgcttga ggaatccttc
    38941 gctggcagca acttcatctt gtaacgcagc atccagacgt cctgcagcca gatcggaata
    39001 gaccaaatcc tggttggcat aggccaccac atccacgcct ttgctacgcc aggtctcgtt
    39061 agcgtaagct tcctgggttg atccctgcag cacaccaaca tgtttacctt tcagtgaatc
    39121 cagcgttggc tgaatcggtg aacctttggc agcaatcaaa cgagaatctg cggcgtacag
    39181 cttgtcggag aaggcaatct cctgctgacg tttatcggta atggaaagcg acgaaataat
    39241 ggcgtcgatt tttttcgctt tcagtgaggg gatcagcgcg tcaaagtcac tggcaaccca
    39301 ggtacatttc acctgcatcc gtttgcacat ctcgttaccg agatcgatat caaagccaac
    39361 aaaatcacct ttagcatctt tcgacgagaa cggcgcatag gtggtatcgg ttccgatacg
    39421 taccgtctcc ggtagcgccg catagctgga agccgctgcg gagagaccga ctaacaaaga
    39481 cagagcgaga atcgacttct tcatacataa ccctcaagtg aaaatggctt ttttatgttg
    39541 tgtattgtgt tgtgtgtttg caggctcttt catgcaggtc ttatgccatc ttgacgacaa
    39601 cagtaacatt caacgttaaa tatgttaata agacgttgca ttattgtcct gaagttgaag
    39661 atagcaggta tagcggttga atcgcagcgt ttcgattgaa tggcagaaac aaaatgtcga
    39721 ggatttgatc gcggttgcaa aattgccctg aaacagggca acagcggagt tatgcgccct
    39781 gccagcgggc aaagagatct tcaggaaggg ttatcgcaaa ctggtcaaga acacgattaa
    39841 ccgtctgatt tatcacatca tcaagggatt gcgggcgatg ataaaacgcc ggaacgggag
    39901 gcataatcac cgcaccgatt tctgccgcct gagtcattaa acgcagatgg cctaagtgca
    39961 atggtgtttc acgcacgcag agcaccaacg ggcgacgctc tttcagcacc acatctgccg
    40021 cacgggtcag taagccatca gtatagctat ggacaatgcc ggaaagggtt ttgattgaac
    40081 agggtaaaat caccatccct agcgtctgga aagaaccgga agagatgctg gcggcaatat
    40141 cgcgcgcatc gtgcgtgaca tcggctaatg cctgcacttc gcgcagagaa aaatccgttt
    40201 cgagggataa ggtctggcgc gctgcctggc tcatcaccag atgcgtttcg atatctgtga
    40261 catcgcgcag aacctgtaat aagcgcacgc cataaatcgc gccgctggcg ccgctgatgc
    40321 ctacaatgag tcgtttcata aatagttgcc ctgtcagact tgcaggcaga ctttgcagga
    40381 tttcggcggg agttgcaagt cagggtgcca gaccggcacc ctcagcgaag gcatcatcct
    40441 tcgttatgca tttcgagatt ttccacttcg ttctgacgtt gcactgcttt ggcgtcatca
    40501 ttacgtaacg tatcgaggaa atcgaggtag ccctgatcaa catctttggt gacgtagacg
    40561 ccgttgaaca ccgagcattc aaactgctgg atatccggat tttcagcgcg aacggcgtcg
    40621 atcagatcgt tcagatcctg gaaaatcaac ccgtcagcac cgatgatctg gcgaatttca
    40681 tcaacttcgc gaccgtgagc gatcagttcc gtggcgctcg gcatatcaat accataaacg
    40741 ttcgggaagc gaatttccgg tgccgcagaa gcgaggtaca ctttcttcgc tccggcttcg
    40801 cgtgccatct cgataatctg ctcagaagtg gtgccacgga cgatggagtc gtcgaccagc
    40861 aggacgtttt tatcgcggaa ctcggcgcgg ttggcattca gtttacggcg cacggactta
    40921 cgacgcagct gctggcccgg catgataaag gtgcggccaa catagcggtt tttaacgaag
    40981 ccctggcggt acggtttgcc cagaatacga gcaatttcca gcgcgatatc acacgaggtt
    41041 tctgggatcg ggatcaccac gtcgatatcc agatcttccc attcgcgggc aattttctcg
    41101 cccagtttcg tgcccatatt cacacgcgcg ctgtaaacgg aaattttgtc gatgaacgag
    41161 tccgggcgag caaagtatac atactcaaac aggcacggat tgctgaccgg attgtcagca
    41221 cattgacggg taaacaactg cccttcttca gtgatgtaaa tcgcttcgcc cggcgcgacg
    41281 tcacgcagga aatcaaagcc cagcgtatcg agcgctacgc tttcggaagc gaccatatat
    41341 tctgtacggt tctcgtcaat atcacgtttt cccagtacca gcggacgaat cccgtttgga
    41401 tcgcggaaag caaccatacc gtggccgata atcatcgcca cacaggcata tgcgccgcgg
    41461 attaagcggt ttgtggcagc aatggcagcg aaaatattgt cggcttccag cgggtagtgg
    41521 cggaagttgt ccagctcgct agcgaagata ttaagcagaa tttccgagtc ggaagtggtg
    41581 ttgatgtggc ggcgtttttc ttcaaacagt tttttacgca actcgtgagc gttggtcaga
    41641 ttgccgttgt gggcaagcgt aatgccatac ggagagttaa cgtaaaacgg ctgcgcttca
    41701 gaggcgctgg agctgccagc cgtagggtaa cgcacatgac caatgcccat attgccctgc
    41761 aaacgctgca tatggcgagc ttcaaataca tcgctcacca gcccgttcgc tttacgcaaa
    41821 cggaagcagt tattggcatc tatggtgatg atgccggcgg catcctgacc gcgatgctga
    41881 agcaccgtta aggcatcata aatcgactgg ttaaccggca taacaccggc gataccgaca
    41941 ataccgcaca tacgtctttt tcctcgttaa gccacatctc agagcactta cgctctgggc
    42001 aagaaacttg acgagctttg cagataatca aaaaaccatc tgatgataaa actgaactgc
    42061 gggatcagct gtgatttgct ccagtcttcg cttttcgaca ccccggtaaa ggagtcgaga
    42121 aagaagagaa tggcggcaac aatcaacaca ccgcgcaacg caccgaaaca gacgcccagc
    42181 acccgatcgg tgcctgacaa ccccgttttc tccaccaact ggcctatcac gaagttcacg
    42241 atagcaccaa cgatcagggt agcgataaac agtaccgcga tggcaattcc atttcgaacc
    42301 agttcgtctt caaagcccgt aaaccagact gacaggtaag tgtagtaatg actggcaaca
    42361 aagaaagcac aaccccatgt caccagcgat aacgcttcac gaacaaagcc gcggatcagg
    42421 ctaaccagag aggaaaaagc aatcaccgcg attatggcgt aatcaatcca gaccatatgt
    42481 gtcccacgat tttacgccct gtcatcctgt tcggggcgca ttctaacaga aaaagaaaac
    42541 gtttgcgtag ggatttcctt cccgcgcatc aataaaaatg gcgctgaaaa aatattcaac
    42601 gccatcgact ttttatgcct ttgcggcatc gtgcaatgcg tgtcggatgc ggcgtaaacg
    42661 ccttatccga cctacggttc taacactgcc caggcctgat aagacgcgcc agcgtcgcat
    42721 caggcaagac tgtattaatt cggcgtatag cccattacca cgccacttaa gccagaaagt
    42781 tgcttcaact cacccagcga acctttcagc ttatctttcg aggcatccgg cccaaccaga
    42841 atacgggtaa ttttaccctg cactggcgtg gatggcgacg tataaacccg ataaccggca
    42901 ccgcgcagct taccgacaat ctcattcact ttatcggcat ttttcagcgc acccagttgc
    42961 acaacatagg ctttacccgt tggcgctgct ttttcttcca cgaccggctt cggttctggc
    43021 ttcggcgcag gtggtgcttc aaccttcggt ttaggcggct ccaccggttt cggcttcggt
    43081 ggggcgaccg gtgcaggttc cggttcaaac tcggtgttat tggctgcaat agtggtcgga
    43141 tcgagcgacg gtgctgcggc atcacctgcc cgcacctctt ccgctgcgcc ttccggcggc
    43201 tgcgtcggca acgcctgggt ggcggctggc atcatatcag gctcatcgcg atcgcccgct
    43261 ttcggcacca gcgggatagc cgcgaactca tcctgataat gttttttctg cccgtccagc
    43321 agccctggaa gtacaatcac ccccagcgcc accagcacga tcgtgcccac taaccgattc
    43381 tgaaacttac ttgccaccgc ttctcctcgc gtcaatcact tccatgacat gtgcgacagt
    43441 gtggaaagaa ccacacacca gcacggtgtc ttccgcttta gcgtccgcca ttgcggcatc
    43501 ccatgcctgc gcaacgctat caaatgattt gccgttaccc aaatgctcaa gcagttgttc
    43561 tgccgtggca ccgcgcggcc cttccagtgg cgcacaatac cagtcatcaa ccacgctttt
    43621 caaccaggcc agagttccgg caatatcttt atcatgtagc ataccgataa ccgccagcac
    43681 gcgcccgttt ttcggtagcg ctttcatacg cccggtgaga tattccgccg catgtggatt
    43741 atgcgcgaca tcaaaaataa cgcgtggcga ctcgctcaca atctggaaac gtcccggcaa
    43801 aattgcgctg gcaatcccgt cgcgaatggc attttcactg acttccagcc cgctggcacg
    43861 cagtgccgcc agcgccgttg cggcattcgg ttgcgggaca agcggcaacg gcagattttc
    43921 cagcgtgccg tgagcatcgc taaacgccca gtcatgatcg gtgacggaat agttccactc
    43981 aacgccccga cgttgtaaca gtgcaccttt ttcctgtgcc acatcagcaa tggtagaagg
    44041 catttccggc tcaccgacaa ttgccggttt ttcgctgcgg aagatgcctg ctttctcgcg
    44101 accaatactt tcgcgatctg gacccagcca gtcggtatga tccagcgcaa tactggttac
    44161 taccgcgaca tcggcatcga caatattggt tgcgtccaga cgaccgccca gccctacttc
    44221 cagaatcacc acgtcaagtt gtgcctgctt gaacagccac aacgccgaca gcgtaccgta
    44281 ctcgaaatag gtcagggaaa tatcaccgcg tgccgattca atctccgcaa aagaggcggt
    44341 gtgggccgat tccggcaatt cctggccctg cacacgtacg cgctcggtat aacgcaccag
    44401 atgcggtgaa ctgtagacgc ccactttgta ccctgccgcc atcagaatcg actccagcgt
    44461 acggcaggtg gtgcctttgc cattcgtacc cgcaacggta aacacaaatg gcgctggttt
    44521 cagaacgcca agacgcgccg cgacctggct cacgcgctca aggccgagat cgatagtttt
    44581 actgtgcagg ttttccagat aagaaagcca cgaagccaga ggcgacgcgg cttgaggagt
    44641 gcgtttgata atcatggtat ccgctgattc gttacggtga gaatagcaaa agggcagagc
    44701 cagtggccct gcccttatca gttatcaggc ctcaggttcc tgatccggta ccgggggtac
    44761 cactacgcct tcacgcggcg cttcaggatt cggcgctggc agattcatca acttcgccag
    44821 aatgctcgcc agtttcaggc gcatttccgg acgacggacg atcatgtcga tggcgccttt
    44881 ctcgatcagg aattcactgc gctggaatcc tggcggcagt ttttcgcgaa cggtctgttc
    44941 gataacacgc ggaccggcaa agccaattaa cgctttcggt tcagcgatgt tgagatcgcc
    45001 cagcatggcg aaacttgcag aaacaccgcc catcgtcggg tcggtcagca cggagatgta
    45061 cggcaagccg cgctcctgca tttttgccag tgccgcagag gttttcgcca tctgcatcag
    45121 cgacatcagt gcttcctgca tacgtgcgcc accagaggcg gagaagcaga tcagcgggca
    45181 gttatcttcc agcgcctgct caacggcacg cacgaaacgt gcacccacaa cagaccccat
    45241 tgaaccgccc ataaaggcga actcgaatgc cgcagcgaca accggcattc catacagagt
    45301 gcctttcatc accaccagcg catctttttc gccagtttct ttctgcgcag atgccagacg
    45361 gtctttatac ttcttggagt cacgaaactt cagcacatct ttcggctcaa gctcgctacc
    45421 cagctccaca aggcttcctt catctaacag gctatgcagg cgattacgcg ctgtcatacg
    45481 catgtgatgg tcacacttcg gacagacctc aagattacgt tccagctcag cgcggtataa
    45541 aacctgaccg cagctatcac acttagtcca caccccttca ggaatgctcg ccttgcgggt
    45601 gggagtaatg ttgcttttaa ttcgttcaat ccagctcatt agggaccttt ctgtctgaac
    45661 ctggttcgat gccagtttta tctttgggga cgcataatgc catttttgcc cccaacagac
    45721 catgaatgtt gcacattaaa acataacagc ccgaaacttt ggataaaaaa gtggtcgaac
    45781 cgcggagtta ctttttattt tgcggcgcgt gccgcagcgc gtttgtgacg aataaattcg
    45841 aaaaccccag gcaatattga aacaaaaata atgccaacaa tcatcagctt aaggttgctc
    45901 tgaatgaagg ggagcgtgcc gaagaaataa cccgcgtagg taaaaatcag tacccacaac
    45961 agtgcgccga tcacgttata agcggcgaaa tgacggtacg acatgtggcc cattcccgca
    46021 acaaacggcg cgaacgttct gacgatcggt acaaaacggg cgagaataat cgttttgccg
    46081 ccatgtctct cgtaaaactg atgagtctta tcaagataac tgcgacgaaa gattttcgaa
    46141 tccgggttac tgaacagttt gtcaccaaat aaccgtccaa tggtatagtt cactgcatca
    46201 ccgacaatag cggcaatcaa cataagcacc accatcatat ggacattgag atcgttagtt
    46261 tccagcgacg ccaatgcacc agcaacaaac agcagcgaat caccaggcag gaatggcgtt
    46321 accaccagcc ccgtttcgca gaacagaatc aaaaacagaa tggcataaac ccagacgccg
    46381 tactccgcga ccagctctgc cagatgcacg tcaatgtgca ggataaaatc gatgaggaaa
    46441 taaatcaggt ccatatttgc ctatgccttg tactcgtcat ctttcaggct gtaactacgt
    46501 tggctacagc ctgaaatgtt ccgagcatta ttctcgttag tccgccagaa atagcgggcc
    46561 cattggcggt tttggaagat cataccggtc agggtaatcc accgcgacca gatacagccc
    46621 ttccgctttt gccgttgctg ccgccagcgt tctgtccttt gccgccagca actctgctat
    46681 ccagctctcc ggctggttgt gggcaccgac ttccatcagg ctgccgacaa tattcctgac
    46741 catatgatgt acaaaggcat tcgctttgat atctaccacc acataaggac cgtgacgcgt
    46801 gacattaata tgcataacgt tacgccacgg ggttcgggac tggcactgca ccgcacggaa
    46861 cgaggtgaaa tcattctcgc ccagcaagca ttgcgcagcc cgatgcatcc gttcagcgtc
    46921 cagcggttcg taaaaatggg ttaccccttt actcagtacc gccgggcgca gccgatgatt
    46981 gtagatgatg tagcgataac ggcgagccgt ggcgctaaat cgggcatgaa aatcatcagg
    47041 tacagcttta acccaacgca cggcgatgtc accaggtaaa ttcgcattta cgcccaaggt
    47101 ccacgccgcg tctttgcgct gcgcggttgt ttcgaaatgc accacttgcc cggtaccgtg
    47161 tacccctgcg tcagtacgcc cggcgcagaa gacggtgatg ggttcgttcg ccacctggga
    47221 gagcgccttt tccagcttct cctgcacact gcggacttca ttctgccgtt gccagccgta
    47281 atacttactg ccgtcgtact caatgcccag cgcaatttta taaactggca gttgttgctg
    47341 gtcggacatt agtacagata ctcctgcacc agtttctcgg cgatttttac tgccatcagc
    47401 gcgccgccaa agcgaacgtt atcggccacc gaccagaact ggacttgctc cggcataccg
    47461 tagtcattac gcacgcagcc aacagaaaga tgcggcgtac ccgaagcatc ccctacctga
    47521 gtcgggaatt cgttctcttc agagagcaca atatcttcgc cctgagcaaa cgcatcacgc
    47581 gcttcttctg ccgccagcgg acgcagtgct tcaaagttga ccatctgggc atgaccgtag
    47641 aataccggtg cctggacgac gcttgccgaa atcatcagcc cttcgtcctg caggattttg
    47701 cgtacttcgt caacgatacg acgttcttca cgcacgctac cttcgctatc cggcaacaac
    47761 ggcagcatat tgaacgccag ttgacgaccg aagaaatctt cttcgtcaat cggaatgccg
    47821 ttgagcaatt tcgcactctg ccccgctaac gcatcgaccg cttttttgcc ctgggcggag
    47881 gctgaaatca ggctggtaac actgatacgc gacaaaccgc cctgatcgat taacggtttc
    47941 agtgccgcca gcagctggct ggtcagactg tctggtacgg cgatgacatt ccggttgcgg
    48001 taatcggtca gtacaaacgg gtttacttcc ggcaccacca gcggtacgtc gggttcgaga
    48061 gcaaacagtc cgctgctgtc gatcaccagg caacctgagt tggtcgcttc ttcaacccag
    48121 gcagcggtag cttctttgcc tgcgacaaaa aatgccagct gcgcctgcgt ccagtcgaat
    48181 tcagcggcat cctgcacggt gattgtctta ccaccaaagc gcagttgttc gcctgcgctt
    48241 tcgttacgtg ccagtgcata aatttcccca accgggaact gacgttcagc cagcgtttca
    48301 agcagggctt cgcccacagc gccagttgcg cccaggacgg caatgttcca gccttcagac
    48361 atggtggttt actccagaaa tagcaaagct ccctgccaat gttacagcag agagcatgaa
    48421 gaagagatta acgtgccgga tgatgaacgg cgttaaaacc cagtttacac agcaatgatg
    48481 ccgcactggc gtcatcacaa attacataca gagatgacca ttcacggcgc tcaagatagt
    48541 ttttgcgcag tttatcgaac tcacccggta tcccggcgac tttacgcagc ggtgcgtcat
    48601 cgcggcgcac atcatacacc aaatgcacca gccttttcag cgtcggttga tcgagcgggc
    48661 catgcagcgt aatgcgacca aactctggcg cgggcagtaa tgtatccagc gcaacgtgct
    48721 gttcatgccc aataaacttg ctataggctt caaacacttg cgtagtaccg cgtgctttac
    48781 cttccagggt ataacctgcg atatgcggcg tgccgatatc cacttttgtc agcaactcca
    48841 cgttaagttc cggttcgcct tcccagacat ccagcactac gcttaacttc tggccttcat
    48901 tcaggcaggt cagcaacgca gtattatcga cgactgcgcc acggcaggcg ttaatcagaa
    48961 tcgctcccgg cttcaggcta cggatcagtt tttcatccgc cagatgcagc gttttgtacg
    49021 gcccatcttt gaagagtggc gtatggaaag tcagaatatc cgcatgctga actaattcat
    49081 ccagcgagcg gaaatcaccc tcatccccac ggtcagcgcg aggcggatcg caaagcaatg
    49141 ttttaatccc taacgcttcc agtcgcgcct gcaatcgacg tccaacgtta ccaacgccca
    49201 cgatccccac cgtacggtcg tgcagtgaaa atccatcgcg ttcggcaagc atcagtagtg
    49261 aggagaaaac atattccacc accgcaatcg cattacagcc aggtgcagcg gaaaaaccaa
    49321 ttcccgcctg cttcaaccat gcttcatcga catggtcggt ccccgcagtg gcagtgccaa
    49381 caaatttaat gggttttcct gccagcaaag attcattcac tttcgtgacc gaacgcacca
    49441 tcagcgcatc cgcgtctgcc agttgagcaa cggggattgg acgcccggga accgcggtca
    49501 cctcacccaa acggctaaat aagtcgcggg cataaggcat attttcatca acaaggattt
    49561 tcacgtttgt gttacctgta tgagacgaga gttaaccgga caagtgtgcc ataatctcgc
    49621 ggccaggcat acttgcgaag atttcaggta taaggatacg taatgataca acctatttcc
    49681 ggccctcctc ctgggcaacc accaggtcag ggagataacc tgccgtctgg cgcgggcaat
    49741 cagcctttat ccagtcagca acgtacttcg ctggaaagct taatgacgaa agtgacctca
    49801 ctgacgcaac aacaaagagc agaactgtgg gcgggtatca ggcacgatat tggtctgtcg
    49861 ggagattcac cgctgctttc gcgtcacttc cctgccgctg agcataatct ggcgcaacgt
    49921 ctgctggccg cgcaaaaaag ccattctgcc cgccagcttt tagcgcaatt aggggagtat
    49981 ttacgtctgg ggaataatcg tcaggcggtc acggattata tccgtcataa ctttggtcag
    50041 acgccgctga atcagctctc accggagcaa ttaaaaacca ttctcaccct gttgcaggaa
    50101 gggaagatgg ttattccgca accacagcag cgcgaggcga ccgaccgtcc tttattaccg
    50161 gcggagcaca atgcgctaaa acagctggtg accaaacttg cggcggcaac gggggaaccc
    50221 agcaaacaga tctggcaatc gatgctggaa ctttccgggg tgaaagatgg cgagttaatt
    50281 ccagcgaaac tgtttaacca tctggtgacc tggttgcagg cgcgccagac gttaagccag
    50341 caaaatacgc cgacgctgga atcactacag atggcgctaa aacaaccttt agatgccagt
    50401 gaactggcgg cgttatcggc atatatccag caaaaatatg gcctttctgc gcaatcatcg
    50461 ctttcttctg cccaggccga ggatattctt aatcagcttt atcaacggcg ggttaaaggg
    50521 attgatccgc gtgatatgca accgctgctt aatccttttc caccgatgat ggacacgttg
    50581 caaaatatgg caacgcgtcc cgcgctgtgg atactgttag tcgcgattat cctgatgctg
    50641 gtctggctgg ttcgttagcc ccgacgaaat gacagtatcg tgacaataat tcccagcacc
    50701 gcagagatcg ccccggcaag aaataccgaa gagtaaccaa acgtggtcgc cagcattccc
    50761 gccagcggcc cggagacgcc gagggcgata tcctgaaacg cggcgtaacc gcccagtgcg
    50821 gtgccgcgaa cttgtgaggg gacgcgttta accacctcca cgcccagcgc aggaaagata
    50881 agcgaacatc cggctccggt taacgccgcg cccgctaatg cgacccacgc acctggggct
    50941 tgccagagca gcaacaagcc caccgtttct acaagcagag agacaatcgc cactttcacg
    51001 ccgccaaaac ggtccggcat ccagccaaac atgacgcgca tcacgacaaa tgcgccgcca
    51061 aacgcggtaa gagtaaagcc cgccatcgcc catcctttgc tggcaaagta gagcgaaacg
    51121 aaagtcccga taaccgcaaa accaacgcct tgtagtgcca gccctaaccc tggtttccag
    51181 ataaacccga caacgctcca cagcgatgga cgttctcccg ccagggccgg tactttgcgc
    51241 actgtgccgt tacaggccca cgccagtaag ggtaatacca ttgtggtgat cgccagtgcg
    51301 gcaaaaccgt aatggctatg aatcaacagg ccaagcggag caccaacagc gagggcaccg
    51361 taaatcgcca ttccattcca tgacatcact ttgccagagt gttttggccc tacgatgcct
    51421 aacccccagg tcagagcgcc tgtcagtaac tggctttcac caaacccaag aatcaaacgc
    51481 ccgatgacca acagggcaaa tttgaacggt gcggagacag gcaaaatcgc cgccagcagc
    51541 aacgcgccgc cagccagacc acaagctaac atcccctgaa gcgccgaacg ttttgcacca
    51601 tattgatcgg ccagtcgccc ggcatagcca cgcgtcagca ccgtagccag aaactgaatc
    51661 ccgacggcaa tcccgaccat ggtattgcca tagcccagat catgatgaac aaacagcggg
    51721 ataaccggca acggcagccc tacggtcatg taggtgagaa aaaccgcaaa agcgatgcgg
    51781 aagagcgaaa aattggcaga agatcgtgtt tcggtttggc ttacagcagt catgcattac
    51841 tccagaatgc agcgcaaggc gaggagtatc cccgtctcat ctctctggtt tcagggttac
    51901 agtgcgttgg caggatttaa cgcgtacgtc ttttcagaag gaaatcgaca aagcgggaag
    51961 tttgcctgga actggcggcg attgtcaatg atgtgaaaaa gggaaccatc aggttccctt
    52021 ttgcgttagt gccggaggcc gcattggcgc gtaacgtcgg atgcgacgct ggcgcgtctt
    52081 atccgaccta ctccgactac tccgacctac tgcgaattaa tctttcagct tgcgcattac
    52141 cagcgtggcg ttggtgccgc cgaagccgaa gctgttagac ataacggtag tcagttcgcg
    52201 atcggtcgtt tcggtcacga tgttcagacc cgcagcctgc tcgtccagct cttcaatgtt
    52261 gatgctcggg gcgataaagc cgtgttccag catcagcaga gagtagatag cttcctgtac
    52321 gccagcagcg cccagagagt gaccggtcat ggctttggtt gcagaaatcg ccgggctctt
    52381 atcgccgaac acttcacgga tagctgccag ttctttcacg tcgccaaccg gagtcgaagt
    52441 accatgagag ttcaggtaat cgattggggt atcaacgccg tgcatcgcca tcttcatgca
    52501 gcgtactgcg ccttcgccag acggagcaac catgtctgca ccatcagagg ttgcgccgta
    52561 gccaacgatt tcagcataga tgtgagcacc acgcgccagc gcgtgttcca gctcttcaac
    52621 cactaccata ccgccgccgc cagcgataac gaaaccgtca cggtgagcgt cgtaagtacg
    52681 ggaggctttt tccggggtgt cgttgtattt agtagacagc gcacccatcg cgtcgaattc
    52741 gcaggccatt tcccagcaca gctcttcgcc gccgccagca aacacgatgt cctgtttgcc
    52801 cagttggatc tgctctactg cgttaccgat acagtgtgcg gaagtcgcac acgcggagct
    52861 gatggagtag ttaacgccat gaattttaaa cggcgtggcg aggcaggcag aaacgccgga
    52921 tgccatcgct ttggtgacca catacgggcc aaccgctttc aggccgcgcg ggccgcgcat
    52981 tgcgtcagcg ccgaacacct ggaaacgcgg ggaaccgccg ccagaacctg caatcaggcc
    53041 aacgcgcggg ttattctggt aagcttccgg agaaaggccc gcatctgcga ttgcctgctc
    53101 catagaaagg aatgcataaa tggatgcgtc gctcataaag cgcacaactt tgcggtcaat
    53161 gaggccagtg gtatccagtt ttacgttgcc ccagacgtgg ctacgcatgc cggaatcctt
    53221 cagctcctga gagaaagtga tccctgaacg tccttcacgc agagatgcca ggacttcctg
    53281 ctggttatta ccgatgctgg aaacaatgcc caggccagta atcactgcac gtttcattca
    53341 atacctctgt aagtcgcaca tagagtaagt ttcgaatgca caatagcgta cacttgtacg
    53401 ccgaacaagt ccgatcagcc atttaataga gaaatttgcg cagccttaca cacatcgcta
    53461 agatcgagcc accgcctgta agacgagtaa cttacgtgaa acactactcc atacaacctg
    53521 ccaacctcga atttaatgct gagggtacac ctgtttcccg agattttgac gatgtctatt
    53581 tttccaacga taacgggctg gaagagacgc gttatgtttt tctgggaggc aaccaattag
    53641 aggtacgctt tcctgagcat ccacatcctc tgtttgtggt agcagagagc ggcttcggca
    53701 ccggattaaa cttcctgacg ctatggcagg catttgatca gtttcgcgaa gcgcatccgc
    53761 aagcgcaatt acaacgctta catttcatta gttttgagaa atttcccctc acccgtgcgg
    53821 atttagcctt agcgcatcaa cactggccgg aactggctcc gtgggcagaa caacttcagg
    53881 cgcagtggcc aatgcccttg cccggttgcc atcgtttatt gctcgatgaa ggccgcgtga
    53941 cgctggattt atggtttggc gatattaacg aactgaccag ccaactggac gattcgctaa
    54001 atcaaaaagt agatgcctgg tttctggacg gctttgcgcc agcgaaaaac ccggatatgt
    54061 ggacgcaaaa tctgtttaac gccatggcaa ggttggcgcg tccgggcggc acgctggcga
    54121 catttacgtc tgccggtttt gtccgccgcg gtttgcagga cgccggattc acgatgcaaa
    54181 aacgtaaggg ctttgggcgc aaacgggaaa tgctttgcgg ggtgatggaa cagacattac
    54241 cgctcccctg ctccgcgccg tggtttaacc gcacgggcag cagcaaacgg gaagcggcga
    54301 ttatcggcgg tggtattgcc agcgcgttgt tgtcgctggc gctattacgg cgcggctggc
    54361 aggtaacgct ttattgcgcg gatgaggccc ccgcactggg tgcttccggc aatcgccagg
    54421 gggcgctgta tccgttatta agcaaacacg atgaggcgct aaaccgcttt ttctctaatg
    54481 cgtttacttt tgctcgtcgg ttttacgacc aattacccgt taaatttgat catgactggt
    54541 gcggcgtcac gcagttaggc tgggatgaga aaagccagca taaaatcgca cagatgttgt
    54601 caatggattt acccgcagaa ctggctgtag ccgttgaggc aaatgcggtt gaacaaatta
    54661 cgggcgttgc gacaaattgc agcggcatta cttatccgca aggtggttgg ctgtgcccag
    54721 cagaactgac ccgtaatgtg ctggaactgg cgcaacagca gggtttgcag atttattatc
    54781 aatatcagtt acagaattta tcccgtaagg atgactgttg gttgttgaat tttgcaggag
    54841 atcagcaagc aacacacagc gtagtggtac tggcgaacgg gcatcaaatc agccgattca
    54901 gccaaacgtc gactctcccg gtgtattcgg ttgccgggca ggtcagccat attccgacaa
    54961 cgccggaact ggcagagctg aagcaggtgc tgtgctatga cggttatctc acgccacaaa
    55021 atccggcgaa tcaacatcat tgtattggtg ccagttatca tcgcggcagc gaagatacgg
    55081 cgtacagtga ggacgatcag cagcagaatc gccagcggtt gattgattgt ttcccgcagg
    55141 cacagtgggc aaaagaggtt gatgtcagtg ataaagaggc gcgctgcggt gtgcgttgtg
    55201 ccacccgcga tcatctgcca atggtaggca atgttcccga ttatgaggca acactcgtgg
    55261 aatatgcgtc gttggcggag cagaaagatg aggcggtaag cgcgccggtt tttgacgatc
    55321 tctttatgtt tgcggcttta ggttctcgcg gtttgtgttc tgccccgctg tgtgccgaga
    55381 ttctggcggc gcagatgagc gacgaaccga ttccgatgga tgccagtacg ctggcggcgt
    55441 taaacccgaa tcggttatgg gtgcggaaat tgttgaaggg taaagcggtt aaggcggggt
    55501 aatctgctct cgcagtgttt gccggatgcg gcgtgaacgc cttatccgac ctacgtgtga
    55561 c
//
LOCUS       DAZUDJ010000027        54686 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.027, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000027 DAZUDJ010000000
VERSION     DAZUDJ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 54686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54686
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.027"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..159
                     /locus_tag="ACHY1N_002194"
     CDS             <1..159
                     /locus_tag="ACHY1N_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HFS4044501.1"
                     /translation="ARIARVHQFGERDQVAPGIFTDYPVRELLGICQADERLIYNTVL
                     GRIAEAVR"
     gene            171..737
                     /locus_tag="ACHY1N_002195"
     CDS             171..737
                     /locus_tag="ACHY1N_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HFS4044502.1"
                     /translation="MRLLSNIIRTGIISEVDEKSWCVRVRSGELETGWLRWNTTRAGA
                     FNVWLPPSPGEQVVIACIGGNPETAMIIGSLWSDASPAPGKSLKEIVVSAPDGAVFRY
                     DADAGALSASGMKTATLQASVSVKLDTPVVECTNLLKTAEIDVTKGGKMSGNITHSGG
                     DFTSNGITVHTHKHGGVKGGSDSTGGPQ"
     gene            734..1084
                     /locus_tag="ACHY1N_002196"
     CDS             734..1084
                     /locus_tag="ACHY1N_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HFS4044503.1"
                     /translation="MTTRYTGMNPDGTGNLNDMEHLKQSVRDILTTPLASRVMRREYG
                     SLVPDLIDEPMNNTTRLQCMSAAVIALTRWEPRIALDAIDVVWKAGGRAGVTLSGTVM
                     QTMQNVELTITLRE"
     gene            1088..1984
                     /locus_tag="ACHY1N_002197"
     CDS             1088..1984
                     /locus_tag="ACHY1N_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFS4044504.1"
                     /translation="MPAVDLSQLPEPAIIAEPDFEAILADTKAMMIASYPAEQREAVS
                     AALELESEPLNVIAQTMSFREMLLRQRVNEGARACMLSHGSGTNLDNLAGNMNTKRLV
                     ITPATDTTDAVMESDTSLRLRAQRAYDGLSVAGPSGAYEYFARSASGLVRDARAISPS
                     PACVTVSILSTEGDGTATEALLNTVRAVLNAEDTRPVADRLTVQSARIVTWRLNAKLY
                     FYPGPESEPILAAAESSFRKWLSEQGLIGQDVALSAIAAALHVHGVQRVEIIEPTQNM
                     AISDIQAARCESFTISEGGRNE"
     gene            1977..2507
                     /locus_tag="ACHY1N_002198"
     CDS             1977..2507
                     /locus_tag="ACHY1N_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HFS4044505.1"
                     /translation="MSNSLLPPSASNFMRCAEAVGTRITDIPVDLNTLWSPDTCPVHL
                     LPYLAWAFSVDRWDRNWPEETKRQVIRDAWLIHRHKGTISALRRAIEPLGYLIRVSEW
                     WEFGGEPGTFTVEVGTLDSGVTEEMYLEMERLIADARPVSRHMTGLNIIQEIPGDIFA
                     AAATYDGEVITIYPDD"
     gene            2510..3355
                     /locus_tag="ACHY1N_002199"
                     /pseudo
     CDS             2510..3355
                     /locus_tag="ACHY1N_002199"
                     /inference="COORDINATES: protein motif:HMM:NF023985.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
     gene            3875..4780
                     /locus_tag="ACHY1N_002200"
     CDS             3875..4780
                     /locus_tag="ACHY1N_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HFS4044506.1"
                     /translation="MASKGQVTALTDNTQGATGLELYEVYNNGYPTAYGNIIHLKGMT
                     AVGEGELLIGWSGTSGAHAPAFIRSRRDTTDANWSPWAQLYTSAHPPAEFYPVGAPIP
                     WPSDTVPSGYALMQGQTFDKSAYPKLAAAYPSGVIPDMRGWTIKGKPASGRAVLSQEQ
                     DGIKSHTHSASVSSTDLGTKTTSSFDYGTKTTSLFDYGTKTTSNAGSHTHSIPTSDGA
                     NQWGKIPLTSGRLATQYTSATTGSSGSHSHTVGIGSHQHTVGIGAHTHSVAIGSHGHT
                     ITVNAAGNAENTVKNIAFNYIVRLA"
     gene            4780..5358
                     /locus_tag="ACHY1N_002201"
     CDS             4780..5358
                     /locus_tag="ACHY1N_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0098004 - virus tail fiber assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HFS4044507.1"
                     /translation="MAFRMSKQSRTLKIYNLLAGTNEFIGDGDAYIPPHTGLPANSTD
                     IAPPDIPAGFVAVFNTDEASWHLVEDHRGYTVYDVASGDALFISELGPLPENVTWLSP
                     EGEFQKWNGTSWVKDAEAEKLFRSQEAEETKNSLMQVASEHIAPLQDAVDLDIATEEE
                     ASLLAAWKTYRVLLNRVDTTVAADIEWPVAPQ"
     gene            complement(5402..5974)
                     /locus_tag="ACHY1N_002202"
     CDS             complement(5402..5974)
                     /locus_tag="ACHY1N_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HFS4044508.1"
                     /translation="MLSYLMAIHFVLFGNSTNLKNFWKHEVIRRKRMDIWRLLREKKQ
                     RNRNFLFWWRLANEMYINGNKLHKKAAKKLNSKIINKFGCEIGLGANIGKGLTIPHHA
                     GIVVHFAVDAGENLVLRQNTTIGQIDGDIPGSRVKIGSNVDIGANCCIIGLSRKIGDN
                     VKIGAMSFINKDIPSNCTYITKKSGVVLYK"
     gene            complement(6131..6619)
                     /locus_tag="ACHY1N_002203"
     CDS             complement(6131..6619)
                     /locus_tag="ACHY1N_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310666.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4044509.1"
                     /translation="MMMIYGMFVFELRTLPHQQLQQNKSWRHVKNERVNRSASWQYIG
                     AGDDRIVLSGVLYPEITGGEVSLSLLTTQAYTGRPWPLIDGVGQIYGMYVLTETNTTR
                     SEFDRYGKAKKIEFSLTLERCDEDLRERLQSSSFSDMLSGFKDKVTSSLNSAASSVKG
                     LL"
     gene            complement(6632..9439)
                     /locus_tag="ACHY1N_002204"
     CDS             complement(6632..9439)
                     /locus_tag="ACHY1N_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000853438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4044510.1"
                     /translation="MKTLDIRVAFSAVDRLTRPAENARRLMGQFGDSIQRTQGAIKNL
                     ERQARSFERARDAVSKADAGIVKARRQLNALNQLQRTGTVLSEKQQKLMQQLSTRLER
                     LNESRTREIQKMRELGGELKRHGISLTGSDNTIQQAIRRTEQYNNQLERERQALARVT
                     RARERYSRAQETAGKLKTGGALAIGAAAAGGYAAGRFLQPAIGFGKEMSRVQALTRID
                     KNSPQFKALREQALKLGSETPFTASDAASGQSFLAMAGFTPQAIQAALPGVLNMALAG
                     GVELGETADIGSNILTQFNLTADQMDRVGDTLTAAFTRTNTDLRALGETMKYTGPVAA
                     KLGISLEEAAAMAGMLASNGLRGSDAGTAMRASLSRLASPPKAAADALKELGVSVADA
                     RGKMRPMEDVLLDLYKATQKYGQVDQVSFFKDIAGEEAFVGLQTLVAAAGSGELQKLT
                     RELQGARGEVDRVAKVMADNLDGDLKNLDSAWEGLRIRISDLVDGPLRSVTQWLTRVL
                     EKITSLAQAHPVLTRQLLIAGGALLAMTATIRSLSLVIGVLYGKLATLRLGFDILTRS
                     MNVVRVLPALWGMLTGSVSLLGGAIGALFSPVGLIVAALAGAAVLIWKYWDPIRAFFA
                     GVFSGIMERLTPLRETFERFGPVFDAIGSGISQVFNWFKSLLSPMESSKETLDKCTSA
                     GEIFGNVLGGALQLVLTPAKMLLDTLAWILEKLGVLPDEAERARKKIEDAQRAAILRD
                     KVALLQGDLAKINPPKPVENGNGTGGDKPKDNKPLTDSNTGTLRRLSKIADNTGKLVD
                     ETKKRIGPGDIVFKNLPRALAVRGEWQERKIAQVSKPAPAINITPVVPAPLPPALVPV
                     VAASSRPVAEAIRSPVASVPVTSRNREPVASGFGGEIHVHLHNVVTQNPRELAKLVGE
                     MVRAEMERRARAGRGSFYDKD"
     gene            complement(9426..9581)
                     /locus_tag="ACHY1N_002205"
     CDS             complement(9426..9581)
                     /locus_tag="ACHY1N_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HFS4044511.1"
                     /translation="MCFEHIEDLVADIAAIFNWSPAEIFMMTPGEVVSWRERAALRSG
                     NADNEDS"
     gene            complement(9590..9964)
                     /locus_tag="ACHY1N_002206"
     CDS             complement(9590..9964)
                     /locus_tag="ACHY1N_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4044512.1"
                     /translation="MKDIDTETRNNTVADDVTAGEDMAVERGVKLTRPIERGGEKITY
                     VEITGAIEQAGSLRGLSLSDVLNLKADTMFMLLPRVTSPRLDEVMIKKMSSRDFIQLC
                     AVAVNFMSEPDSGAKSVQETAA"
     gene            complement(10020..10532)
                     /locus_tag="ACHY1N_002207"
     CDS             complement(10020..10532)
                     /locus_tag="ACHY1N_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HFS4044513.1"
                     /translation="MAVPKHLRFFTLFVDGENEVGKVTSVTPPKLTRKTDSYRGGGMM
                     GAVSIDLGLDDSALDASFVMGGAVRALFLKYGGTIDGTLLRFAGEYYTDAESDLYEIE
                     MRGRVTEIDMGEAKQGEATSHTYAVKNTYYKLSVNDRPLWEIDLLNHIYRKDGKDIVP
                     DRIRSALGLG"
     gene            complement(10532..11716)
                     /locus_tag="ACHY1N_002208"
     CDS             complement(10532..11716)
                     /locus_tag="ACHY1N_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HFS4044514.1"
                     /translation="MSETRFHGARVTENTDLVTAINDVDSSVIGIVATADDADAKLFP
                     LNKPTLLTRVNDVLGKCGTTGTLYRALKAIADQVSTKVIVVRVAEHKEEDGKTQDQLV
                     IGGSEDDGSYTGMYALLVAEQDESIGYRPRILAAPELDTEAVTKSLCVIAGKLRAFVY
                     ATCHGCNTMAEAITYRQKFNEREVMLLWPDFIAYNPKSGKNETFPAPAYACGLRAYID
                     HEQGWHKSLSNVPVKNVLGMSRHVFWSLQAEDSDANSLNNKEITTIIRRNGFRFWGNR
                     TPETNAYIFEVYTRTAQVLADSIAEAQFETIDSPLTPANVKDVISAIRAKLDSLVTAG
                     KLIGAECWYDVVDNGTTDLRQGRVRIRYKYTPVPPLEDMELYQTFTDEFFGPAFAVLG
                     GA"
     gene            complement(12139..12222)
                     /locus_tag="ACHY1N_002209"
                     /pseudo
     CDS             complement(12139..12222)
                     /locus_tag="ACHY1N_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_305381.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12183..12983
                     /locus_tag="ACHY1N_002210"
     CDS             12183..12983
                     /locus_tag="ACHY1N_002210"
                     /inference="COORDINATES: protein motif:HMM:NF017739.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="contractile injection system protein, VgrG/Pvc8
                     family"
                     /protein_id="HFS4044515.1"
                     /translation="MTVSARSADFRDEFNVKREVSWHDVTVERVVSAIAHRYGLKPQI
                     SEMLMDIEIDHADQTEESDMSFLTRMAEMLGAITTVKSGNLLFIMPGGGVNAQGQPLP
                     SFAITRSSGDRHQFRIADREAYTGVRAYWLDLNYGKKKKVSVKRRKPPKPKKEKSSSR
                     EGDYMEGAEGNVFVLRKTYQNEQAARRAAAAKWQQLQRGAASFSITLARGRAELYPEM
                     HGTVTGFKSEIDNQDWIIAKAEHTIDNSGFTTQLELEAKIPEWIAETE"
     gene            13026..13286
                     /locus_tag="ACHY1N_002211"
     CDS             13026..13286
                     /locus_tag="ACHY1N_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001512982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HFS4044516.1"
                     /translation="MFRCPLCGASARIRTSRPENDSNTVRQKYYQCNNLECGVCFSTL
                     EAFHKFTSKHASGVHSSEGIPWHELPASHRGNNQMSLPLPQN"
     gene            13476..13616
                     /locus_tag="ACHY1N_002212"
     CDS             13476..13616
                     /locus_tag="ACHY1N_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HFS4044517.1"
                     /translation="MSQKSLTAITFCVTVILIIWMLHGSLCEIRMSFWGAEFAAFLQC
                     KQ"
     gene            complement(13806..14087)
                     /locus_tag="ACHY1N_002213"
     CDS             complement(13806..14087)
                     /locus_tag="ACHY1N_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_305382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044518.1"
                     /translation="MRCGLLMAICLCLVSFSGYAATGKSDAQIKKEIIKESIESYPGN
                     CACPYNHARNGSRCGGRSAYSRTGGYDVVCYESDVTDEMIRQWKQENAE"
     gene            complement(14628..14714)
                     /locus_tag="ACHY1N_002214"
     tRNA            complement(14628..14714)
                     /locus_tag="ACHY1N_002214"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14678..14680),aa:Leu,seq:taa)
     gene            complement(14727..14800)
                     /locus_tag="ACHY1N_002215"
     tRNA            complement(14727..14800)
                     /locus_tag="ACHY1N_002215"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14766..14768),aa:Cys,seq:gca)
     gene            complement(14855..14930)
                     /locus_tag="ACHY1N_002216"
     tRNA            complement(14855..14930)
                     /locus_tag="ACHY1N_002216"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14895..14897),aa:Gly,seq:gcc)
     gene            complement(15082..15630)
                     /gene="pgsA"
                     /locus_tag="ACHY1N_002217"
     CDS             complement(15082..15630)
                     /gene="pgsA"
                     /locus_tag="ACHY1N_002217"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFS4044519.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAV
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSASRADLLDQ"
     gene            complement(15687..17519)
                     /gene="uvrC"
                     /locus_tag="ACHY1N_002218"
     CDS             complement(15687..17519)
                     /gene="uvrC"
                     /locus_tag="ACHY1N_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFS4044520.1"
                     /translation="MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETAS
                     QNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEV
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRY
                     GKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGVDRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            complement(17516..18172)
                     /gene="uvrY"
                     /locus_tag="ACHY1N_002219"
     CDS             complement(17516..18172)
                     /gene="uvrY"
                     /locus_tag="ACHY1N_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HFS4044521.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCR
                     TNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
                     "
     gene            18314..18385
                     /locus_tag="ACHY1N_002220"
                     /pseudo
     CDS             18314..18385
                     /locus_tag="ACHY1N_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001302039.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            18468..18644
                     /gene="yecU"
                     /locus_tag="ACHY1N_002221"
     CDS             18468..18644
                     /gene="yecU"
                     /locus_tag="ACHY1N_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YecU"
                     /protein_id="HFS4044522.1"
                     /translation="MIKIFIGHYINVFYSTADITLKKQPLLFLAKLMVYSAALTFFTA
                     NFHCNMTRKINEYA"
     gene            18631..18855
                     /gene="yecF"
                     /locus_tag="ACHY1N_002222"
     CDS             18631..18855
                     /gene="yecF"
                     /locus_tag="ACHY1N_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein YecF"
                     /protein_id="HFS4044523.1"
                     /translation="MSTPDFSTAENNQELANEVSCLKAMLTLMLQAMGQADAGRVMLK
                     MEKQLALIEDETQAAVFSKTVKQIKQAYRQ"
     gene            complement(18922..19644)
                     /gene="sdiA"
                     /locus_tag="ACHY1N_002223"
     CDS             complement(18922..19644)
                     /gene="sdiA"
                     /locus_tag="ACHY1N_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HFS4044524.1"
                     /translation="MQDTDFFSWRRTMLLRFQRMEAAEEVYHEIELQAQQLEYDYYSL
                     CVRHPVPFTRPKVAFYTNYPEAWVSYYQAKNFLAIDPVLNPENFSQGHLMWNDDLFSE
                     AQPLWEAARAHGLRRGVTQYLMLPNRALGFLSFSRCSTREIPILSDELQLKMQLLVRE
                     SLMALMRLNDEIVMTPEMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQKNM
                     QKKINAPNKTQVACYAAATGLI"
     gene            complement(19874..20626)
                     /gene="tcyN"
                     /locus_tag="ACHY1N_002224"
     CDS             complement(19874..20626)
                     /gene="tcyN"
                     /locus_tag="ACHY1N_002224"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_process: GO:0003333 - amino acid transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     TcyN"
                     /protein_id="HFS4044525.1"
                     /translation="MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTV
                     LENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMD
                     QGRIVEQGAAKALFADPQQPRTRQFLEKFLLQ"
     gene            complement(20623..21291)
                     /gene="tcyL"
                     /locus_tag="ACHY1N_002225"
     CDS             complement(20623..21291)
                     /gene="tcyL"
                     /locus_tag="ACHY1N_002225"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HFS4044526.1"
                     /translation="MQESIQLVIDSLPFLLKGAEYTLQLSIGGMFFGLLLGFILALMR
                     LSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAY
                     AAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQE
                     REPK"
     gene            complement(21306..22292)
                     /gene="dcyD"
                     /locus_tag="ACHY1N_002226"
     CDS             complement(21306..22292)
                     /gene="dcyD"
                     /locus_tag="ACHY1N_002226"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416429.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019148 - D-cysteine desulfhydrase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HFS4044527.1"
                     /translation="MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTP
                     MAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGG
                     SNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGV
                     TVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLA
                     RLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV"
     gene            complement(22397..23197)
                     /gene="tcyJ"
                     /locus_tag="ACHY1N_002227"
     CDS             complement(22397..23197)
                     /gene="tcyJ"
                     /locus_tag="ACHY1N_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015276 - ligand-gated monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4044528.1"
                     /translation="MKLAHLGRQALMGVMAVALVAGMSVKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRID
                     VVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTIKTAADLKGKKVGVGLGTNY
                     EEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEA
                     FSRQESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK"
     gene            complement(23285..23836)
                     /gene="fliZ"
                     /locus_tag="ACHY1N_002228"
     CDS             complement(23285..23836)
                     /gene="fliZ"
                     /locus_tag="ACHY1N_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HFS4044529.1"
                     /translation="MMVQHLKRRPLSRYLKDFKHSQTHCAHCRKLLDRITLVRDGKIV
                     NKIEISRLDMLLDENGWQVEQKSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEM
                     SPGTAREYVVRLRRLGNHLHEQNISLDPLQDGFLDEILAPWLPTTSTNNYRIALRKYQ
                     HYQRQTCTGLVQKSSSLPASDIY"
     gene            complement(23882..24601)
                     /gene="fliA"
                     /locus_tag="ACHY1N_002229"
     CDS             complement(23882..24601)
                     /gene="fliA"
                     /locus_tag="ACHY1N_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HFS4044530.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVERYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TDDHQRENPLQQLLDSNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            complement(24766..26259)
                     /locus_tag="ACHY1N_002230"
     CDS             complement(24766..26259)
                     /locus_tag="ACHY1N_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HFS4044531.1"
                     /translation="MAQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDD
                     AAGQAIANRFTANIKGLTQASRNANDGISVAQTTEGALNEINNNLQRIRELSVQATNG
                     TNSDSDLTSIQSEIQQRLSEIDRVSGQTQFNGVKVLASDQDMTIQVGANDGETITIKL
                     QEINSDTLGLSGFGIKDPTKLKAATAETTYFGSTVKLADANTLDADITATVKGTTTPG
                     QRDGNIMSDANGKLYVKVAGSDKPAENGYYEVTVEDDPTSPDAGKLKLGALAGTQPQA
                     GNLKEVTTVKGKGAIDVQLGTDTATASITGAKLFKLEDANGKDTGSFALIGDDGKQYA
                     ANVDQKTGAVSVKTMSYTDADGVKHDNVKVELGGSDGKTEVVTATDGKTYSVSDLQGK
                     SLKTDSIAAISTQKTEDPLAAIDKALSQVDSLRSNLGAIQNRFDSAITNLGNTVNNLS
                     SARSRIEDADYATEVSNMSRAQILQQAGTSVLAQANQTTQNVLSLLR"
     gene            26514..27926
                     /gene="fliD"
                     /locus_tag="ACHY1N_002231"
     CDS             26514..27926
                     /gene="fliD"
                     /locus_tag="ACHY1N_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001616262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_component: GO:0009421 - bacterial-type flagellum
                     filament cap [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HFS4044532.1"
                     /translation="MASFTSLGVGSNLPLDTLLNNLTIAEKKRLNPITQQQSDNTARL
                     TAYGTLKSALEKFQTANTALNKADLFKSTTVTSSNEDLKVSTEAGAAPGIYTISVTQL
                     AQAQSLRTDSPTIIASTKDALGDESSDTRTIKITQDGRKEPLEIKLNKDQTSLDEISK
                     AINDADSGISASIVKVKDGNYQLVLTASEGLANKMTISVEGDSKLNDLLAYDSKTNTG
                     NMKELVNAQNAQLNVNGIDIERSSNKITDAPQGVTLDLTKKVTDVRVTVTKSNDKATE
                     AIKGWVDSYNSLIDTFNTLTKYKEVDPGAEAQDKNNGALLGDSVVRTIQSGIRAQFAN
                     GASDGAFKTLNEIGIKQDGTTGKLKIDDDKLKKVLNENTASVRELLVGDGKETGITTK
                     IATEVKGYLADDGIIDSAQDSINATLKKLTKQYLSVSASIDDTVARYTAQFTQLDTMM
                     SKLNNTSTYLSQQFTAMSNS"
     gene            27941..28351
                     /gene="fliS"
                     /locus_tag="ACHY1N_002232"
     CDS             27941..28351
                     /gene="fliS"
                     /locus_tag="ACHY1N_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HFS4044533.1"
                     /translation="MYTASGSKAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRARL
                     FMQDNNQQGKGVSLSKAINIIENGLRVSLDEESKDELTQNLIALYSYMVRRLLQANLR
                     NDVSAVEEVEALMRNIADAWKESLLSPSLIQDPV"
     gene            28351..28716
                     /gene="fliT"
                     /locus_tag="ACHY1N_002233"
     CDS             28351..28716
                     /gene="fliT"
                     /locus_tag="ACHY1N_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA];
                     GO_process: GO:1902209 - negative regulation of
                     bacterial-type flagellum assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HFS4044534.1"
                     /translation="MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAV
                     QEIAHLTEEVAPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSV
                     LSAYGDQGGFVLAPQDNFS"
     gene            28794..30281
                     /gene="amyA"
                     /locus_tag="ACHY1N_002234"
     CDS             28794..30281
                     /gene="amyA"
                     /locus_tag="ACHY1N_002234"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0005509 - calcium ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HFS4044535.1"
                     /translation="MRNPTLLQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPA
                     YKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDKAQLLAAIDALKRNDIAVLLDVV
                     VNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSKFIWDFKCF
                     SGIDHIENPDEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTQCDGFRLDAVKHIPAWFYKEWIEHVQEVAPKPLFIVAEYWSHEVDKLQT
                     YIDQVEGKTMLFDAPLQMKFHEASRMGRDYDMTQIFTGTLVEADPFHAVTLVANHDTQ
                     PLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGAHYEDVGGDGQTYPIDMPII
                     EQLDELILARQRFAHGVQTLFFDHPNCIAFSRSGTDEYPGCVVVMSNGDDGEKTINLG
                     ENYGNKTWRDFLGNRQESVVTDENGEATFFCNGGSVSVWVIEEVI"
     gene            complement(30315..30728)
                     /gene="yedD"
                     /locus_tag="ACHY1N_002235"
     CDS             complement(30315..30728)
                     /gene="yedD"
                     /locus_tag="ACHY1N_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310694.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YedD"
                     /protein_id="HFS4044536.1"
                     /translation="MKKLAIAGALMLLAGCAEVENYNNVVKTPAPDWLAGYWQTKGPQ
                     RALVSPEAIGSLIVTKEGDTLDCRQWQRVIAVPGKLTLMSDDLTNVTVKRELYEVERD
                     GNTIEYDGMTMERVDRPTAECAAALDKAPLPTPLP"
     gene            30915..32120
                     /gene="yedE"
                     /locus_tag="ACHY1N_002236"
     CDS             30915..32120
                     /gene="yedE"
                     /locus_tag="ACHY1N_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HFS4044537.1"
                     /translation="MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYV
                     QLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFTALMLIIGWEKRFFRRA
                     APQTAKEIA"
     gene            32117..32350
                     /gene="yedF"
                     /locus_tag="ACHY1N_002237"
     CDS             32117..32350
                     /gene="yedF"
                     /locus_tag="ACHY1N_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HFS4044538.1"
                     /translation="MKNIIPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
     gene            32459..33127
                     /gene="yedK"
                     /locus_tag="ACHY1N_002238"
     CDS             32459..33127
                     /gene="yedK"
                     /locus_tag="ACHY1N_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HFS4044539.1"
                     /translation="MCGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKV
                     LLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSRMFKPLWQHGRAICFADG
                     WFEWKKEGDKKQPYFIYRADGQPVFMAAIGSTPFERGDEAEGFLIVTAAADQGLVDIH
                     DRRPLVLSPEAAREWMRQEIGGKEASEIATNGCVPANQFTWHPVSRAVGNVKNQGAEL
                     IQPV"
     gene            complement(33520..33834)
                     /gene="fliE"
                     /locus_tag="ACHY1N_002239"
     CDS             complement(33520..33834)
                     /gene="fliE"
                     /locus_tag="ACHY1N_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HFS4044540.1"
                     /translation="MSAIQGIEGVISQLQATAMSARAQDSLPQPTISFAGQLHAALDR
                     ISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSM
                     QV"
     gene            34049..35707
                     /gene="fliF"
                     /locus_tag="ACHY1N_002240"
     CDS             34049..35707
                     /gene="fliF"
                     /locus_tag="ACHY1N_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body MS-ring/collar protein
                     FliF"
                     /protein_id="HFS4044541.1"
                     /translation="MNATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAK
                     APDYRTLFSNLSDQDGGAIVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGL
                     PKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELSRTIATIGPVKGARVHLAMPKPS
                     LFVREQKSPSASVTVNLLPGRALDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLT
                     QSNTSGRDLNDAQLKYASDVEGRIQRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTE
                     EQYRPNGDESHAALRSRQLNESEQSGSGYPGGVPGALSNQPAPANNAPISTPPANQNN
                     RQQQASTTSNSGPRSTQRNETSNYEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGK
                     PLPLSNEQMMQIEDLTREAMGFSEKRGDSLNVVNSPFNSSDESGGELPFWQQQAFIDQ
                     LLAAGRWLLVLLVAWLLWRKAVRQQLTRRAEAMKAVQQQAQAREEVEDAVEVRLSKDE
                     QLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWINNDHE"
     gene            35700..36695
                     /gene="fliG"
                     /locus_tag="ACHY1N_002241"
     CDS             35700..36695
                     /gene="fliG"
                     /locus_tag="ACHY1N_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HFS4044542.1"
                     /translation="MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANV
                     TQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRD
                     TASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
                     IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAV
                     REFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLR
                     NMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV"
     gene            36688..37374
                     /gene="fliH"
                     /locus_tag="ACHY1N_002242"
     CDS             36688..37374
                     /gene="fliH"
                     /locus_tag="ACHY1N_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HFS4044543.1"
                     /translation="MSDNLPWKTWTPDDLAPPQAEFVPMVEPEETIIEEAEPSLEQQL
                     AQLQMQAHEQGYQAGIAEGRQQGHEQGYQEGLARGLEQGLAEAKSQQAPIHARMQQLV
                     SEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGK
                     PQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQE
                     LCRLAAPGVV"
     gene            37374..38747
                     /gene="fliI"
                     /locus_tag="ACHY1N_002243"
     CDS             37374..38747
                     /gene="fliI"
                     /locus_tag="ACHY1N_002243"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HFS4044544.1"
                     /translation="MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGL
                     QLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAE
                     GLQSGKQLPLGPALLGRVLDGSGKPLDGLPSPDTTETGALITPPFNPLQRTPIEHVLD
                     TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKD
                     FIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTR
                     YAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGGSITAFYTVLTEGDD
                     QQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFK
                     QLLSSFQRNRDLVSVGAYAKGSDPMLDKAIALWPQLEGYLQQGIFERADWEASLQGLE
                     RIFPTVS"
     gene            38766..39209
                     /gene="fliJ"
                     /locus_tag="ACHY1N_002244"
     CDS             38766..39209
                     /gene="fliJ"
                     /locus_tag="ACHY1N_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HFS4044545.1"
                     /translation="MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLID
                     YQNEYRNNLNSDMSAGMTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWR
                     EKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE"
     gene            39206..40333
                     /gene="fliK"
                     /locus_tag="ACHY1N_002245"
     CDS             39206..40333
                     /gene="fliK"
                     /locus_tag="ACHY1N_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HFS4044546.1"
                     /translation="MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTD
                     KAAPQLLVATDKPTTKGELLISDIVSDAQQADLLIPVDETLPVINVEQSTSTPLTTAQ
                     TMTLAAVADKNTTKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDVPSTVLPAEKP
                     TLFTKLTSAQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPH
                     QTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLK
                     VDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ
                     QQQSQRTVNHEPLAGEDDDTLPVPVSIQGRVTGNSGVDIFA"
     gene            40438..40902
                     /gene="fliL"
                     /locus_tag="ACHY1N_002246"
     CDS             40438..40902
                     /gene="fliL"
                     /locus_tag="ACHY1N_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009425 - bacterial-type flagellum basal
                     body [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HFS4044547.1"
                     /translation="MTDYAISKKSKRSLWIPILVFITLAACASAGYSYWHSHQVAADD
                     KAQQRVVPSPVFYALDTFTVNLGDADRVLYIGVTLRLKDEATRSRLSEYLPEVRSRLL
                     LLFSRQDAAVLATEEGKKNLIAEIKTTLSTPLVAGQPKQDVTDVLYTAFILR"
     gene            40907..41911
                     /gene="fliM"
                     /locus_tag="ACHY1N_002247"
     CDS             40907..41911
                     /gene="fliM"
                     /locus_tag="ACHY1N_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HFS4044548.1"
                     /translation="MGDSILSQAEIDALLNGDSEVKDEPTASVSGESDIRPYDPNTQR
                     RVVRERLQALEIINERFARHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNL
                     NLIHLKPLRGTGLVVFSPSLVFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
                     ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNIC
                     LPFSMIEPLRELLVNPPLENSRNEDQNWRDNLVRQVQHSQLELVANFADISLRLSQIL
                     KLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTLNGQYALRIEHLINPILNSLNEEQPK
                     "
     gene            41908..42321
                     /gene="fliN"
                     /locus_tag="ACHY1N_002248"
     CDS             41908..42321
                     /gene="fliN"
                     /locus_tag="ACHY1N_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HFS4044549.1"
                     /translation="MSDMNNPADDNNGAMDDLWAEALSEQKSTSSKSAADAVFQQFGG
                     GDVSGTLQDIDLIMDIPVKLTVKLGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN
                     GYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR"
     gene            42324..42689
                     /gene="fliO"
                     /locus_tag="ACHY1N_002249"
     CDS             42324..42689
                     /gene="fliO"
                     /locus_tag="ACHY1N_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0044781 - bacterial-type flagellum
                     organization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthetic protein FliO"
                     /protein_id="HFS4044550.1"
                     /translation="MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGF
                     VPKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEI
                     PQPDFQSVMKNLLKRSGRS"
     gene            42689..43426
                     /gene="fliP"
                     /locus_tag="ACHY1N_002250"
     CDS             42689..43426
                     /gene="fliP"
                     /locus_tag="ACHY1N_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310714.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HFS4044551.1"
                     /translation="MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQT
                     LVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMS
                     PVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
                     GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA
                     LPFKLMLFVLVDGWQLLVGSLAQSFYS"
     gene            43436..43705
                     /gene="fliQ"
                     /locus_tag="ACHY1N_002251"
     CDS             43436..43705
                     /gene="fliQ"
                     /locus_tag="ACHY1N_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HFS4044552.1"
                     /translation="MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQI
                     NEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTLFTNLPYIIG"
     gene            43714..44499
                     /gene="fliR"
                     /locus_tag="ACHY1N_002252"
     CDS             43714..44499
                     /gene="fliR"
                     /locus_tag="ACHY1N_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthetic protein FliR"
                     /protein_id="HFS4044553.1"
                     /translation="MMQVTSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKL
                     GLAMMITFAIAPSLPANDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEII
                     GLQMGLSFATFVDPASHLNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG
                     GEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGF
                     PLTLTVGISLMAALMPLIAPFCEHLFSEMFNLLADIISELPLI"
     gene            44789..45412
                     /gene="rcsA"
                     /locus_tag="ACHY1N_002253"
     CDS             44789..45412
                     /gene="rcsA"
                     /locus_tag="ACHY1N_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HFS4044554.1"
                     /translation="MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACD
                     SQRPSVVFINEDCFIHDASNSQHIKHIINQHPNTLFIVFMAIANVHFDEYLLVRKNLL
                     ISSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISD
                     QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR"
     gene            complement(45456..45644)
                     /gene="dsrB"
                     /locus_tag="ACHY1N_002254"
     CDS             complement(45456..45644)
                     /gene="dsrB"
                     /locus_tag="ACHY1N_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HFS4044555.1"
                     /translation="MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGI
                     WFFNEAGHQDGIFVEKAE"
     gene            45807..46034
                     /gene="yodD"
                     /locus_tag="ACHY1N_002255"
     CDS             45807..46034
                     /gene="yodD"
                     /locus_tag="ACHY1N_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid resistance protein YodD"
                     /protein_id="HFS4044556.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQNDSEHV
                     SVDGREYHTWRELADAFELDIHDFSVSEVNR"
     gene            46332..47147
                     /gene="yedP"
                     /locus_tag="ACHY1N_002256"
     CDS             46332..47147
                     /gene="yedP"
                     /locus_tag="ACHY1N_002256"
                     /EC_number="3.1.3.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050531 - mannosyl-3-phosphoglycerate
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0051479 - mannosylglycerate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
                     /protein_id="HFS4044557.1"
                     /translation="MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLREANVPVI
                     LCSSKTSAEMLYLQKTLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEISQ
                     VLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQ
                     FTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGKRPTTLGLGDGPND
                     APLLEVMDYAVIVKGLNREGVHLHDEDPTRVWRTQREGPEGWREGLDHFFSAR"
     gene            complement(47144..48838)
                     /gene="dgcQ"
                     /locus_tag="ACHY1N_002257"
     CDS             complement(47144..48838)
                     /gene="dgcQ"
                     /locus_tag="ACHY1N_002257"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator diguanylate
                     cyclase DgcQ"
                     /protein_id="HFS4044558.1"
                     /translation="MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWRE
                     VVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAV
                     TEFEQHRDEHAWQIELNRRRTLPFNGVSDALVSEGNLLSRENESLDNEITAALEVGYL
                     LRLAHNSSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRH
                     RAVRWFTSQPEHASNTEPQVTVSVPVDSNNYWYGVLGMSIPVRTMQQFLRNAIDKNLD
                     GEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDSRYVSWERL
                     DHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQS
                     SLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQ
                     AGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGASLTEAAEVAERIRLKLNEKE
                     MLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVCASDNA"
     gene            complement(49009..49191)
                     /gene="yodC"
                     /locus_tag="ACHY1N_002258"
     CDS             complement(49009..49191)
                     /gene="yodC"
                     /locus_tag="ACHY1N_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2158 domain-containing protein"
                     /protein_id="HFS4044559.1"
                     /translation="MSFMVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGYGVKREAFH
                     ETELVPGEGSRSAEEV"
     gene            complement(49270..50187)
                     /gene="yedI"
                     /locus_tag="ACHY1N_002259"
     CDS             complement(49270..50187)
                     /gene="yedI"
                     /locus_tag="ACHY1N_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="HFS4044560.1"
                     /translation="MLLAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLN
                     AQQVSGVRANRELPVVWGVAKGSLINKVILVPLALIISAFIPWAITPLLMIGGAFLCF
                     EGVEKVLHMLEARKHKEDPAQSQQRLEKLAAQDPLKFEKDKIKGAIRTDFILSAEIVA
                     ITLGIVAEAPLLNQVLVLSGIALVVTVGVYGLVGVIVKIDDLGYWLAEKSSALMQALG
                     KGLLIIAPWLMKALSIVGTLAMFLVGGGIVVHGIAPLHHAIEHFAGQQSAVVAMILPT
                     VLNLILGFIIGGIVVLGVKAVAKMRGQAH"
     gene            50360..51280
                     /gene="yedA"
                     /locus_tag="ACHY1N_002260"
     CDS             50360..51280
                     /gene="yedA"
                     /locus_tag="ACHY1N_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HFS4044561.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LAAGILLMAFLLLRGHKLPPLRPLLNAALIGLLLLAVGNGMVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSI
                     SWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGETLSKIEWLALGVI
                     VFAVVLVTLGKYLFPAKPVVAPVIQDASSE"
     gene            complement(51269..51739)
                     /gene="vsr"
                     /locus_tag="ACHY1N_002261"
     CDS             complement(51269..51739)
                     /gene="vsr"
                     /locus_tag="ACHY1N_002261"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VSPR family DNA mismatch endonuclease"
                     /protein_id="HFS4044562.1"
                     /translation="MADVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDA
                     SLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKIGKNVERDRRDIS
                     RLQELGWRVLIVWECALRGREKLTDEALSERLEEWICGEGASAQIDTQGIHLLA"
     gene            complement(51720..53138)
                     /gene="dcm"
                     /locus_tag="ACHY1N_002262"
     CDS             complement(51720..53138)
                     /gene="dcm"
                     /locus_tag="ACHY1N_002262"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-cytosine methyltransferase"
                     /protein_id="HFS4044563.1"
                     /translation="MQENISVTDSYSTGNAAQAMLEKLLQIYDVKTLVAQLNGVGENH
                     WSAAILKRALANDSAWHRLSEKEFAHLQTLLPKPPAHHPHYAFRFIDLFAGIGGIRRG
                     FESIGGQCVFTSEWNKHAVRTYKANHYCDPATHHFNEDIRDITLSHKEGVSDEAAAEH
                     IRQHIPEHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFACDTQGTLFFDVVRIIDSRRP
                     AMFVLENVKNLKSHDQGKTFRIIMQTLDELGYDVADAEDNGPDDPKIIDGKHFLPQHR
                     ERIVLVGFRRDLNLKADFTLRDISECFPAQRVTLAQLLDPMVEAKYILTPVLWKYLYR
                     YAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRGWDMAKGEKDFDDP
                     QNQQHRPRRLTPRECARLMGFEAPGEAKFRIPVSDTQAYRQFGNSVVVPVFAAVAKLL
                     EPKIKQAVALRQQEAQHGRRSR"
     gene            complement(53205..53900)
                     /gene="yedJ"
                     /locus_tag="ACHY1N_002263"
     CDS             complement(53205..53900)
                     /gene="yedJ"
                     /locus_tag="ACHY1N_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HFS4044564.1"
                     /translation="MDLQHWQAQFENWLKNHHQHQGAAHDVCHFRRVWATAQKLAADD
                     DVDMLVILTACYFHDIVSLAKNHPQRQRSSILAAEETRRLLREEFEQFPAEKIEAVCH
                     AIAAHSFSAQIAPLTTEAKIVQDADRLEALGAIGLARVFAVSGALGVALFDGEDPFAQ
                     HRPLDDKRYALDHFQTKLLKLPQTMQTARGKQLAQHNAHFLVEFMAKLSAELAGENEG
                     VDHKVIDAFSPAG"
     gene            complement(53940..54221)
                     /gene="drpB"
                     /locus_tag="ACHY1N_002264"
     CDS             complement(53940..54221)
                     /gene="drpB"
                     /locus_tag="ACHY1N_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DrpB"
                     /protein_id="HFS4044565.1"
                     /translation="MEERLSRSPGGKLALWAFYTWCGYFVWAMARYIWVMSRIPDAPV
                     SGFESDLGSTAGKWLGALVGFLFMALVGALLGSIAWYTRPRPARSRRYE"
BASE COUNT        13576 a        14382 c        13642 g        13086 t
ORIGIN      
        1 gcacgtattg cacgcgttca tcagttcggt gagcgcgatc aggttgcgcc gggcattttc
       61 accgattacc cggtacgtga gctgctgggt atctgccagg cagatgaacg cctgatttat
      121 aacacggtgc tgggccggat tgcggaggct gtacggtgag cgcagaactc atgcgactgc
      181 tgagcaacat catccgcacc gggattatct ctgaagttga tgagaagtcc tggtgcgtgc
      241 gcgttcgcag cggcgaactg gaaacaggct ggttgcgctg gaacaccacg cgcgcgggag
      301 ccttcaatgt gtggctgccg ccatcacccg gcgaacaggt ggtaattgcc tgcattggcg
      361 gcaacccgga aaccgccatg ataattggca gcctgtggag tgatgccagt ccggcacccg
      421 gcaaaagcct gaaagaaatc gtggtcagcg cgccggacgg cgcggtgttc cgctacgacg
      481 cggacgcagg cgcactgagt gccagcggca tgaaaacggc cactttgcag gcatccgtca
      541 gcgtgaaact ggatacgccc gtcgtggaat gcacaaacct tctgaaaaca gccgagattg
      601 acgtcacaaa agggggaaag atgagcggca atatcacgca cagtggcggc gatttcacct
      661 caaacggcat cacagtgcat acgcataagc acggtggcgt taaaggtggc agcgattcga
      721 caggaggccc gcagtgacaa cccgctacac aggaatgaat ccggacggaa cgggaaacct
      781 gaacgatatg gagcacctga aacagtcagt cagggacatc ctgaccaccc cgctggcaag
      841 ccgggttatg cgacgggaat atggcagcct tgtgcctgat ttgattgacg aacccatgaa
      901 taacaccacg cgtctgcaat gcatgagcgc tgccgtgatt gcactgacac gatgggaacc
      961 ccgcattgcc ctggacgcca tcgacgttgt ctggaaggca ggaggccgcg ccggggtgac
     1021 gctgtcgggc actgtcatgc agaccatgca gaatgttgaa ttaaccatca cgctgagaga
     1081 gtaaatcatg cctgccgttg acctttccca gttaccggaa cccgccatca tcgcggagcc
     1141 tgactttgag gcaattctgg ctgacacaaa ggccatgatg attgcgtcct atcccgccga
     1201 acagcgtgaa gccgtttccg ccgcgctgga gctggaatcg gaacccctta acgttatcgc
     1261 tcaaaccatg tcgtttcgtg aaatgctgtt acgccagcgg gttaacgagg gcgcacgcgc
     1321 ctgcatgtta agccacggtt cagggacaaa cctggacaac ctcgcgggca atatgaacac
     1381 aaagcgcctg gttatcactc cggcaacgga taccaccgac gcggtgatgg agagcgacac
     1441 ctcgctgaga ctgcgggcgc agcgggcgta tgacggcctg agtgttgcag gcccgtcagg
     1501 cgcatacgag tattttgcac gcagcgccag cggtctggtg cgtgatgcgc gggccatcag
     1561 cccgtctccg gcctgtgtga cggtttccat cctgtccaca gagggcgacg gcacagcaac
     1621 ggaggcgttg cttaataccg ttcgcgctgt tctgaatgca gaggataccc gcccggtggc
     1681 cgaccgcctt actgtacaga gcgccagaat cgtgacatgg cggctgaatg caaaactgta
     1741 cttttacccc ggcccggaat ccgaacctat tctggccgcg gcggaatcgt cgttcaggaa
     1801 gtggctgtct gagcaggggc ttatcggtca ggacgtggcg ttgtcagcca ttgctgccgc
     1861 actgcatgtg cacggtgtgc aacgcgtgga gataatcgaa cccacacaga atatggccat
     1921 cagcgacata caggcggcgc gctgtgagtc attcaccatc agcgaaggtg ggcgtaatga
     1981 gtaattcact gttaccgcca tcagccagca atttcatgcg ttgtgccgaa gctgtcggaa
     2041 cgcgcattac agacattccg gtagacctca acacgctgtg gtcgccggac acctgcccgg
     2101 tgcatctgct gccttatctc gcctgggcat tttccgttga ccgctgggat cgcaactggc
     2161 cggaagagac aaagcgacag gttattcgtg atgcatggct gatacaccga cacaaaggga
     2221 ccatcagcgc actgcgccgg gccattgagc cgctgggata cctcattcgt gtgtctgagt
     2281 ggtgggagtt cggcggagaa ccgggaacat ttaccgttga agtcggcacg ctggacagtg
     2341 gcgtgacgga ggaaatgtat ctggaaatgg agcggttgat tgctgatgcc cgcccggtca
     2401 gccgccacat gacagggctg aatatcattc aggagatccc gggggatatt ttcgcggcgg
     2461 cagcaactta cgacggtgaa gtcattacca tttatccgga cgattaagca tgagtaccac
     2521 aacacgaaaa tttaaaacca ttatcactga tactggtgcc aaaaaattag ctcaggcagc
     2581 cgcgccagat ggtaatcctg tccacctgac tcacatggcc gtgggcgacg gtggcggcac
     2641 gttgcccaca ccagacagta agcagacccg tctggtgcat gaggtgtggc gacatactgt
     2701 taatcgcgtc atcctggacg caacacatca gaaccgcatt attgcggagc tggttattcc
     2761 tcctgaaacg ggcggattct ggatccggga aattggtgta tttgatgagc acggcgattt
     2821 gatcgcggtg ggcaatactg ccgaaagtta caagccagcc gttgccgaag gatccggacg
     2881 tgcacaaaca tttcgcacca ttctgaccgt atccagcact gccaccgtgg cgcttaccgt
     2941 ggataacacc atggttatgg ccacagtgga ttacgtgaat gacaaactga aagaacatga
     3001 acagtcacga cgtcacccgg acgcctcgct gaccgcaaaa ggctttgttc aactcagtag
     3061 cgccaccaac agcacgtctg aagcactggc cgcaacgccg aaagcggtca aggcagccta
     3121 tgaccttgct aacgggaaat ataccgcaca ggacgccact acagcgcgaa aaggcattgt
     3181 ccagctcagt agcgccacca acagcgattc agaaacgctg gcggcaacac caaaggcggt
     3241 aaaggcagcc tatgacctgg ctaacgggaa atacaccgca caggatgcaa caacagcaca
     3301 gaaagggata atccagctaa gcagcgcgac caacagcaca tctgaaacgc ttgccgcgac
     3361 accaaaggca gtaaaaacag cctatgacaa tgctgagaaa cgtctgcaga aagatcagaa
     3421 cggtgcggat atccctggca aagacacctt tacgaaaaat attggtgcct gccgtgcctt
     3481 cggtgggtca gtaagcacaa caacaggaaa ctggacgact gcacagttta tcgagtggct
     3541 ggattctcag ggagcattta accatccata ctggatgtgc aagggttcct ggtcttatgg
     3601 caataataaa atcattactg atactgactg cggtaatatt catctcgccg gagctgtcat
     3661 tgaagtaatg gggataaagt cagcgatgac gatccgcatt accacaccga ccacctccac
     3721 tggtggtgga acaactaacg cccagtttac ctatattaat cacggaacag attattcacc
     3781 tggctggcga agggactata actccagaaa taagccaacg gcatcagaga tcggggcgtt
     3841 accgtcaggt ggaacagcag tatcatcagt taatctggct tcaaaaggtc aggtaaccgc
     3901 gctgacagac aatacgcagg gggcaacagg tcttgagtta tacgaggtgt ataacaacgg
     3961 atatccaaca gcgtatggaa atatcattca cctgaaaggg atgacagccg ttggcgaagg
     4021 tgagttactc atcggctgga gtggtacaag cggtgctcat gctccggcat ttattcgttc
     4081 acgacgggat acgaccgacg caaactggtc gccgtgggcg cagctttaca cctcggctca
     4141 tcctcctgca gagttttatc cagtcggtgc accaatcccg tggccatcag ataccgttcc
     4201 gtctggttat gccctgatgc aggggcagac ttttgacaaa tctgcctacc cgaaacttgc
     4261 agccgcttat ccgtcaggcg tgatccctga tatgcgtggc tggacgatta agggcaagcc
     4321 cgccagtggt cgtgccgtat tgtctcagga acaggacggc attaaatcgc acacccacag
     4381 cgccagcgta tccagtacgg atttgggtac gaaaaccaca tcgtcgtttg attacgggac
     4441 gaaaacaacc tcactatttg actatgggac caaaactacc agtaacgccg ggagtcacac
     4501 gcattcaata ccaacatcag atggtgcaaa ccagtggggg aaaattccac tgacatctgg
     4561 gcgtctggca actcaatata catcagcaac aacaggttcc tctggctcac attctcatac
     4621 tgtaggtatt ggttctcatc agcacactgt cggtattggt gcacacacgc actccgttgc
     4681 gattggctca catggacaca ccatcaccgt aaacgctgct ggtaacgcgg aaaacaccgt
     4741 caaaaacatc gcatttaact atattgtgag gcttgcataa tggcattcag aatgagtaaa
     4801 caatcacgaa ccctcaaaat ttataatctg ctggccggaa ctaatgaatt tattggtgac
     4861 ggtgacgcat atattccacc tcatacaggt ctacctgcaa acagtaccga tattgcaccg
     4921 ccagatattc cggctggctt cgtggctgtt ttcaacactg atgaggcatc gtggcatctc
     4981 gttgaagacc atcggggtta taccgtctat gacgtggctt ccggcgacgc gttatttatt
     5041 tctgaacttg gcccattacc ggaaaatgtc acctggttat ccccggaagg ggagtttcag
     5101 aagtggaacg gtacatcctg ggtgaaagat gcagaagcag aaaaactgtt tcggagccag
     5161 gaggcggaag aaacaaaaaa cagcctgatg caggtagcta gcgagcatat tgcgccactt
     5221 caggatgctg tagatttgga tattgcgacg gaagaagagg catcgttact ggctgcatgg
     5281 aagacatatc gggtattgtt gaatcgtgtt gatacaacag tagcagcgga tattgagtgg
     5341 ccagtcgccc cacaataaaa agaaaaagcc atcgatagaa atatcgatgg ctttatgtgc
     5401 tctatttata caatacaaca ccgctctttt tagttatata tgtgcagttc gatggtatat
     5461 ctttatttat aaaagacatt gcgcctattt ttacattatc cccgatttta cgtgataatc
     5521 caatgatgca acaattagct ccgatatcaa cgttactacc aatttttact cttgaaccag
     5581 gtatgtcacc atctatctgt ccaatcgtag tattctgtcg taataccaga ttttcacctg
     5641 catcaacagc aaaatgaaca acaattccag catgatgggg aattgttaac ccttttccaa
     5701 tatttgctcc caatcctatt tcacaaccaa atttgttaat tattttactg tttaactttt
     5761 tggctgcttt tttatgtaat ttattaccat taatatacat ttcgttagcc aaccgccacc
     5821 agaaaaggaa attccggtta cgctgctttt tctctcttaa aagcctccag atatccatac
     5881 gtttccgccg aattacttca tgtttccaga agttttttaa attagtagag ttcccaaata
     5941 aaacaaagtg aattgccatt aagtaagaca gcacgaaaat ctccttaatt attatttcag
     6001 accacacatg ttataaggtt aagagattat aaaatcctgt tatttgttat tcaaaaacaa
     6061 ttttctgaga aggacataca acagcaagtc gccagtcacc ttcatcagga aattggcgac
     6121 atacgttaaa tcagagcagc cccttaactg agctggccgc gctattaagg gatgatgtca
     6181 ccttatcttt gaagccggac aacatatcgc tgaacgatga ggattgcagg cgctcccgca
     6241 aatcctcatc acagcgttca agagtcagtg aaaattctat ctttttcgcc ttaccgtagc
     6301 gatcaaactc ggagcgggtc gtattcgttt cagtcaggac atacatgccg taaatctgcc
     6361 cgacgccatc aatcaaaggc cagggtcgtc ctgtatacgc ctgcgtggtc agcagcgaca
     6421 gcgacacttc gccacctgta atttcaggat aaagcacacc agaaagaacg atgcgatcat
     6481 cacctgcacc gatatactgc cagcttgctg aacggttaac gcgttcattt ttcacatgcc
     6541 gccagctttt gttttgctgt aactgctgat gcggcagcgt gcgcagctca aaaacaaaca
     6601 tgccgtagat catcatcatg gccatgactc ctcaatcttt atcgtaaaaa ctgccacgcc
     6661 cggcacgggc acgccgttcc atttctgccc tgaccatttc accgaccagt ttcgccagtt
     6721 cgcggggatt ctgcgtaaca acgttatgca gatgaacatg aatttcacca ccaaatccgg
     6781 aggcaacagg ctcccggtta cgggaagtta caggaactga tgccactgga gatcgtatgg
     6841 cctccgccac cgggcgggag ctggccgcaa caacagggac cagcgccgga ggcagcggtg
     6901 ccgggaccac gggggtgata ttaattgcgg gggcaggctt actgacctgc gcaatcttcc
     6961 gctcctgcca ctccccacga acagcaagtg cgcggggcag gttcttaaag acaatatcgc
     7021 cggggccaat gcgttttttc gtctcatcaa ccagcttacc tgtgttatca gcaattttgc
     7081 tgagtctgcg tagcgtcccg gtattgctgt ctgtgagcgg tttgttgtct ttgggtttat
     7141 cacctccggt gccattgcca ttttccacag gcttcggcgg attgattttc gccaggtccc
     7201 cctgaagtaa ggcaaccttg tcccgaagaa tggccgcacg ctgtgcgtct tcgattttct
     7261 tgcgcgccct ttcagcttca tccggaagga cgccaagttt ttcaagtatc cacgccagcg
     7321 tatccagtag catttttgca ggtgtcagaa caagttgtaa cgcaccgcca agaacgttac
     7381 cgaatatctc gccagcactg gtacatttat ccagcgtttc cttgctggac tccatcggtg
     7441 acagcagcga tttaaaccag ttaaacacct ggctgatccc gcttccgatt gcgtcaaaaa
     7501 cagggccaaa ccgttcaaag gtttcgcgca acggggtcag cctttccata atcccgctga
     7561 acaccccggc aaaaaatgcc ctgatgggat cccagtattt ccagataaga acggcagctc
     7621 cggcaagcgc agccacgata agaccaaccg gactgaacag cgccccgata gcgcctccca
     7681 gcaaagaaac ggaacccgtc agcattcccc acagcgcagg caacaccctg acgacattca
     7741 ttgaccgggt aagaatgtca aaaccaagac gcagggtggc cagctttccg taaagcaccc
     7801 caataaccag cgacaacgag cgaatcgttg cagtcattgc cagcaacgca ccgcctgcta
     7861 tcagtagctg gcgtgtcagt accggatggg cctgcgccag cgaggtgatt ttttcaagca
     7921 cccgcgtgag ccactgcgtg acagaacgca gcggaccgtc aaccagatca ctgatgcgaa
     7981 tacgaagacc ttcccatgcg ctgtcgagat ttttcaggtc cccatcaaga ttatcggcca
     8041 ttacttttgc gacgcgatcg acctctcccc ttgccccctg caattctctg gtcagttttt
     8101 gcagctctcc tgaaccagcc gccgcaacaa gcgtctgcaa accaacgaac gcctcttctc
     8161 cggcgatgtc cttgaagaag gaaacctggt ccacctgtcc gtatttttgt gtcgccttat
     8221 agagatcaag cagcacatcc tccatcgggc gcattttgcc cctggcgtca gcaactgaca
     8281 cccccagctc tttcagcgca tcagccgcag cttttggcgg tgatgcaagg cgggacagac
     8341 ttgcgcgcat ggccgtacca gcatcgcttc cacgaagacc attactggca agcatcccgg
     8401 ccatggctgc cgcttcttca agactgatac caagttttgc ggcaaccgga ccggtatact
     8461 tcatggtttc gcccagcgcg cgtaaatcag tattggtccg ggtgaatgcc gctgtcagcg
     8521 tatcgccaac ccggtccatt tgatcggctg tcaggttgaa ctgtgtgagg atattggagc
     8581 ctatatcagc cgtctcgccg agttcgacgc cacctgccag cgccatatta agaacaccgg
     8641 gcaatgcggc ctgaatggcc tgcggagtaa aaccagccat tgccagaaag ctctgcccac
     8701 tggcggcatc actcgcagta aacggtgttt cagatccaag ttttaacgcc tgctcacgca
     8761 gcgccttaaa ctgcgggctg tttttgtcga ttcgcgtcag tgcctgaacg cgggacatct
     8821 ctttgccgaa cccgatcgca ggctgcaaaa aacgcccggc agcatagccg cccgccgctg
     8881 ccgcaccaat tgccagtgca ccacctgttt tcagttttcc cgctgtttcc tgcgcgcgcg
     8941 aataccgctc acgcgcccgc gttacacgcg caagcgcctg ccgttcgcgt tcaagctggt
     9001 tgttgtactg ttcggtgcgt ctgatggcct gctggatggt gttatcgctg cctgtcaggg
     9061 aaatgccgtg gcgtttcagc tctccgccaa gctcccgcat tttttgaatt tcccgtgtgc
     9121 gcgattcatt caggcgttca agccgggtgc ttaactgctg catcagcttt tgttgttttt
     9181 cgctgagcac tgtacccgta cgttgtaact gattaagggc gttaagctgg cgtcgtgctt
     9241 tcacgatgcc agcatccgct ttactgacag cgtcacgggc gcgctcaaat gaacgcgcct
     9301 gacgctcgag atttttaatc gccccctgcg ttcgctggat ggagtcacca aactgcccca
     9361 tcaggcggcg ggcgttttcg gcaggccggg tcagcctgtc aacggcgctg aaagcgaccc
     9421 ggatatcaag agtcttcatt atctgcattc ccgctgcgaa gtgccgcccg ctcgcgccag
     9481 ctaaccactt cgccgggcgt catcatgaag atttcggcgg gcgaccagtt aaaaatggcg
     9541 gcaatatccg ccaccagatc ttcgatgtgc tcaaagcaca ccagggtgat tacgctgccg
     9601 tctcctgcac gctcttcgcg ccagagtctg gctcgctcat aaaatttaca gccacagcgc
     9661 acaactgaat aaaatcgcgt gacgacattt ttttaatcat cacttcatcc agtcgtggcg
     9721 aggtcacgcg aggcaacagc ataaacatgg tatccgcttt cagattcagc acatcagaca
     9781 gcgacagacc acgcagggat ccagcctgct caatagcccc ggtgatctcc acatacgtga
     9841 ttttttcgcc accacgctca attggtcggg tcagttttac gccacgttcg acagccatat
     9901 cctcacctgc cgtcacatca tccgccacgg tgttattccg ggtttcagta tcgatgtctt
     9961 tcatcagttg tctccttttc agtcagaggc gacgcactgc gccgcctgca tattacttat
    10021 cagccaagcc caagcgcgga acggatacgg tcaggcacaa tgtccttgcc gtccttccgg
    10081 tagatgtggt tcaacaggtc gatttcccac agcgggcgat cgttaacgct cagcttgtag
    10141 taggtgtttt tgacagcgta agtgtgtgat gtggcttccc cctgtttggc ttcccccata
    10201 tcaatttccg tcacacgccc gcgcatctcg atctcataca gatcgctttc tgcatcggtg
    10261 tagtattcac ccgcaaaacg cagcagcgtg ccgtcaatcg tgccgccata tttaaggaac
    10321 agcgcacgaa cagctccccc cataacaaaa ctcgcatcaa gcgcggagtc gtccagaccg
    10381 agatcaatac ttaccgcccc catcatgcca ccaccacgat agctgtcggt tttgcgcgtc
    10441 agtttgggcg gcgtgacgga tgtcactttg cccacttcgt tttcaccatc cacaaacaac
    10501 gtaaaaaagc gaagatgttt tggcacagcc atcaggcacc tcccagcacc gcaaatgcgg
    10561 gaccaaagaa ttcatcggta aacgtctggt aaagctccat gtcttccagt ggcggaacgg
    10621 gcgtatattt gtagcgaata cgcacacgtc cctgacgtaa atccgtggtg ccgttatcca
    10681 ccacgtcata ccagcactcc gcaccaatca gtttcccggc agtaaccagc gaatccagtt
    10741 ttgccctgat ggcactgata acatccttca cgttcgcagg cgtcagtgga ctgtcgatgg
    10801 tttcaaactg cgcttccgca attgaatcag ccagcacctg tgcggttcgg gtatacacct
    10861 caaagatgta ggcgttcgtt tccggtgtgc ggttgcccca gaagcggaac ccgttgcgac
    10921 gaataatggt cgtgatttct ttgttattga ggctgttggc atcactgtct tcggcctgca
    10981 acgaccagaa cacatgcctg gacattccca gcacattttt aaccggaaca ttggacagcg
    11041 atttgtgcca gccctgctca tggtcaatgt acgcacgaag gccgcacgca taagcaggcg
    11101 cggggaacgt ttcgtttttg ccacttttcg ggttgtaggc gatgaagtca ggccataaga
    11161 gcatcacctc acgttcgttg aatttctggc ggtaggtaat cgcctcagcc atcgtgttac
    11221 aaccatgaca tgtggcatac acaaacgcgc gcagtttacc cgcaatcacg cacagggatt
    11281 ttgtcaccgc ctccgtgtcc agctccggcg cggccagaat acgcggacgg tatccgatgc
    11341 tttcatcctg ctctgcaaca agcagcgcat acatccccgt atagctgccg tcatcctcag
    11401 aaccaccgat aaccagttga tcctgcgtct taccgtcttc ttctttgtgt tcagccacgc
    11461 gaacgacgat cacctttgtg ctcacctggt ctgcgatggc cttaagcgca cgataaagcg
    11521 tccccgttgt tccgcatttt cccagcacgt cattgacgcg ggtcagcagt gtaggcttgt
    11581 tcagcgggaa cagcttcgcg tccgcatcat ccgccgttgc cacgataccg ataacgctgg
    11641 aatcaacatc gttaatcgct gttaccaggt cggtattttc cgtaacacgg gcaccatgaa
    11701 aacgagtttc actcatagct tcagcccctt gtatccgtta aatgattcgg caacaatcat
    11761 cacccaccac gcgcgtaatc tcacccctgc gccgttctcc cgacccggcg acaacaaaaa
    11821 gcagtaaccc cctccgcacg cacatgcgac catgccgcac agggagggaa cagatgaccg
    11881 acaccaccat gcaattgctc agtcagggca cagaccccgt aaaaatgccg gattttgata
    11941 ttctcgcgga gggtaaaacg ctgtccggcg tggcagagcg cctgatgagc ctgtcgctga
    12001 ccgacaaccg gggatttgag gcagaccagc tcaccatcac gctggatgat gcggatggtc
    12061 agttgcggct accgccacgg ggcgcgcgcc tgacggttct cattggctgg aaaggcgaac
    12121 cgctgacaga aaaaggctct tacattgttg atgaaatcgc acacgaagga ccgccggaca
    12181 ggctgactgt ttcagccaga agcgcagatt ttcgggatga atttaacgtt aaacgtgagg
    12241 tgtcctggca tgatgtgacc gttgagcgtg tggtatccgc catcgctcat cggtacggtc
    12301 tgaaaccgca aatcagcgaa atgctgatgg atatcgaaat cgaccacgcc gaccagaccg
    12361 aagaaagtga catgtccttc cttacgcgca tggcggaaat gctgggcgca atcaccacgg
    12421 taaaaagcgg taatctgtta ttcatcatgc ccggcggtgg cgtgaacgca cagggccagc
    12481 cgttgccatc gttcgccatc acacgcagca gcggcgatcg ccatcagttc cgcattgctg
    12541 accgcgaggc gtatacgggg gtacgcgctt actggcttga tcttaattac gggaaaaaga
    12601 aaaaagtcag cgtgaaacgc cgcaaaccgc caaaaccgaa aaaagagaaa agcagcagcc
    12661 gtgaaggtga ttatatggaa ggcgcggaag gcaatgtgtt tgtgttacgc aagacttatc
    12721 agaacgagca ggcagcaaga cgcgcagcgg cggcaaagtg gcaacaacta caacgcggag
    12781 ccgcatcatt ctccatcacg ctggcacgtg gacgagcaga actctacccc gaaatgcatg
    12841 gcacggtaac aggatttaaa agcgagattg ataatcagga ctggattatt gcaaaagccg
    12901 agcacaccat tgataacagc ggctttacca cgcagcttga gcttgaggca aaaatcccgg
    12961 aatggatagc ggaaacagag tgagcaactt agaatagcgg cagcaccacg ttaaaggagg
    13021 tcgctatgtt ccgttgtccg ctttgtggcg catctgcccg tatccgcacc agtcgtccgg
    13081 aaaatgattc aaacaccgtg cggcaaaagt attaccagtg taacaacctg gaatgcggcg
    13141 tatgcttctc aacactggaa gctttccata aattcacatc gaaacacgcc tccggcgttc
    13201 actcatcaga aggtatcccg tggcatgagc tgccagcttc acacagggga aacaatcaga
    13261 tgagtttgcc tttacctcag aattaacagg cagaattgcc ggagtaacaa aaaagcgata
    13321 gattacgtgc gggtgccttt cggctgatgg tcggagggaa tacccgaagg ccggatgtgg
    13381 aaaggccccg gaaaacattt ctgtttaacc gaggccctaa cccgtcaacc tagcaagtga
    13441 taggttagcg cctctccaac aaaggagcaa gcgctatgtc gcaaaaatcg cttacggcca
    13501 tcacgttctg cgtgacggta atcctcatca tctggatgct gcacggttcg ctgtgtgaaa
    13561 tacggatgag cttctgggga gcggagtttg cggcgttctt acagtgtaag cagtaaggaa
    13621 accgcgacgg ggaggcaact ccccgtcaat cggttgctag ggtaaggccg ataaggcacc
    13681 ctatctcata ggcatgaata acaaccccgc agcgtaaaaa ctgcggggtt tctttttgga
    13741 actctcacta gctagtgagc cgttaactgc acataatgct cgcacaacaa atcagttaaa
    13801 agagattact cagcattctc ctgcttccat tgccggatca tttcatcggt aacatcactt
    13861 tcataacata ccacgtcata ccctccagta cggctatatg cactgcgtcc accacatcta
    13921 ctaccattcc ttgcatgatt atacggacac gcacaattgc ctggataaga ttcaatggat
    13981 tctttaatta tttctttctt gatctgagca tctgactttc ctgttgctgc atacccacta
    14041 aaagatacca aacaaaggca gattgccatt aataaaccac atcgcatacc gatacactct
    14101 attactaacc aatcatagcc cacatcataa aatcgagatg aggagtacaa cacctttaac
    14161 aagaaggtgc catcacgata atatgccgtg caattcatca aaaaaaagat ctatatcaaa
    14221 gagatagagt tattatcagt gctgcagaca tcagcattcg aggcagcaga aagacagtaa
    14281 atctaacgaa tttgtctttt tctcaggatg ttgtcagatt aaaaaagata gagtagcgca
    14341 gacacctttt ggtggatggt aggaggaaaa atgaagttga gtgggaagat cccagaaaaa
    14401 actttggttt aaccaaggcc ctagttcaat atgcgaaatg cagatgagtt gcaggagagt
    14461 tttgcttcac ccttagagtt taaacagacg tgtactatca ttatttctgc atatcgccac
    14521 accatcgcca ctttaccgcc atttaacaaa atacaaatac aaaaaaacca cccgaaggtg
    14581 gtttcacgac actgcttatt gctttgattt tattcttatc tttcccatgg tacccggagc
    14641 gggacttgaa cccgcacagc gcgaacgccg agggatttta aatcccttgt gtctaccgat
    14701 tccaccatcc gggctcggga agaaagtgga ggcgcgttcc ggagtcgaac cggactagac
    14761 ggatttgcaa tccgctacat aaccgctttg ttaacgcgcc aaattcttca ggcctttcag
    14821 ccagacatcc gcttgacgcc gatgtctttt aaactggagc gggaaacgag actcgaactc
    14881 gcgaccccga ccttggcaag gtcgtgctct accaactgag ctattcccgc attcatcaag
    14941 caatcagtta atcacttgat tttattatcg tctggcaatc agtgccgccg ttcgatgcgt
    15001 tgcattctac ttacctggcg cgatgagtca acgatatttt tcaccacttt tgatcgtttg
    15061 ctgaaaatta cgccgaaacg atcactgatc aagcaaatct gcacgcgaag cgctcaaata
    15121 ttgcaacatt gaccacagag tcagtaccgc agccacaaag aaaagtgcaa taccggcgta
    15181 ctcaacccaa atgttcggac gccacagcag ccaggccaac gccaccatct gggcagtggt
    15241 tttcactttc ccaatccagg agacagccac gctactgcgt ttacccaact ccgccatcca
    15301 ttcgcgtagc gcagaaataa taatttcacg ggcgatcatc gttgccgccg gtagggtcac
    15361 ccaccagctg tgataatgct cggttaccag caccatggcg atagccacga gaactttatc
    15421 tgctacaggg tcaaggaaag caccaaaccg ggtactctgg ttccagcggc gtgccagaaa
    15481 accatcgaac cagtcagtca ccgccgcgac gcagaaaatg agcgcggcgg caaacggcga
    15541 ccaggtgaca ggcagataaa agaccaatac aaagaatggg ataaggatga cacggaacag
    15601 tgtaagcaac gtagggatat taaattgcat aatgacgggt aactatctgt tgtcagtaag
    15661 attaccccta tgttgctaca gagacatcaa tgtttcaacg accagaagat cttttctgcc
    15721 agaccttgcg aaatacccgg cacttttgca atttcctcga cgctggcgtt acgtaaacct
    15781 tgcaaaccgc ccatatattt caacaacatt tgccgacgtt ttggcccgac gccttcaatg
    15841 gtttccaggg agctggtatt tttgaccttc gcccgttttt tacggtgccc gccaatcgcg
    15901 tgatcgtgtg attcatcgcg aatatgctgg ataacatgca gcgcgggaga atctggcggc
    15961 aaactgaatc cctcaccttc cggctcaaag aacagtgttt ccagcccagc cttacgatct
    16021 actcctttgg caacgccaag tagcagtgga tgatttttat cccatgagac atccagttcg
    16081 gcgaagacat ttttcgcctg cgcaagctgg cctttgccgc cgtcgataag gatcacatcc
    16141 gggatcttac tgtcgtcaat ggctttacca taacgccgac gcagcacctg attcatcgcc
    16201 gcataatcat cgcccggcgt gatgcctgta atgttatagc gccgatactc cgcacgcagc
    16261 gggccgttag catcaaacac cacacaggaa gcgacggttt gttcgcccat ggtatggctg
    16321 atgtcaaagc actccatccg cttcacttcc ggcaatttca acacgctggc aagcgcggtc
    16381 agtcgctggt gaacggtaga ttgctgcgaa agtttgctgg ttaaggccgt cgccgcattg
    16441 gtgcgcgcga gtttcagata acgcgcccta tcgccgcgag gtttggtttg aacattaatc
    16501 ttgcgtcccg ccagttctga aagggaatcg gcgagcagcg ttttatcgct aagattaaaa
    16561 tcgagcagga tctcacccgg taaggtgcgc atctggctgc cttgtaaata gaactggcct
    16621 acgaaggttt ctaccacctc gctcagttcc gtaccgccag gcactttcgg gaaatagctg
    16681 cggctgccga gcactttgcc ctgacgaatg aacaatacgt ggacacaagc catgcccgca
    16741 tcgaacgcca caccaataac gtcgaggtcg tcgccggtat tggaaacgaa ttgtttttcg
    16801 gtgacgcgtc gcaccgcctg aatttggtcg cgaatacgtg cagcttcttc aaactccaga
    16861 ttctggctgg cagtttccat acgactaatg agttgcgtaa gcacctgatc atctttgcca
    16921 gacaaaaaca ggcgcacata ctcgacctgc tgagcgtatt cttcttcact caccagtcct
    16981 tcaacgcacg gtcccagaca gcgccctatc tggtattgca gacacggacg cgagcgattg
    17041 cgataaacac tattttcgca ctggcgaatg gggaaaatct tttgcagtag cgccagtgtt
    17101 tcacgtacgg catagccatt cgggaacggg ccgaaatatt cacctttggc atgcttcgca
    17161 ccacgatgca tcgccagacg cgggtgggta tcaccactca ggaagataaa aggatatgat
    17221 ttatcatcgc gtagcaaaac gttgtaacgc ggctgataga gtttgatgta gttgtgttcc
    17281 agcaacagcg cttcggtttc tgtgtgagta accgttacat caatttgctg gatctgggcg
    17341 accagcgctt cggttttgcg cgaagcgagg ttgctacgga aatagctgga aagccgtttt
    17401 ttcaggtctt tcgctttgcc gacatagata accgtaccac cagcatcgta catgcgataa
    17461 acgcctggct ggctggttac ggtttttaaa aacgcttttg cgtcaaactg atcactcact
    17521 gacttgataa tgtctccgca ttacacagac catggcgaat tgccaggtga gtcagctcaa
    17581 catcgccatg aatgtttagt ttactgaaca tacgatagcg gtagctgttc accgttttcg
    17641 gactgagatt gagctgttct gagatctcat tgaccttctg gcccttggtg atcatcagca
    17701 taatctgcaa ttcacgttca gacaaactgg caaatgggct ttctgttttt tctggttcga
    17761 tctggcttaa cgccatttgt tgagcgatgt cagaagcaat gtaacgctgc cctgaataga
    17821 cagaacgaat cgcactcaca acttcctgcg gagccgcgcc tttgctgagg tagcccgcag
    17881 caccggcctg catgactttc gctggtaaag ggttttctgt atggacggta agcatgatga
    17941 ttttgacatc agctgtggaa cgcgcgattt tacgcgtcgc ctcaagaccg ccaatgcccg
    18001 gcatactcat gtccattagc accacgtcaa cggcatttgt ccggcaccac ttaacggcgt
    18061 cttcaccgca cgatgcctca ccgacgactt ttataccctt tatatcttcc agaatgcgtc
    18121 gtatccctgc gcgcaccagt tcgtggtcat caacaagtag aacgttgatc aaaggaatat
    18181 ctccagaaat agggataacg ctactgatag ttagtcattc gtatattagc ggtttttatt
    18241 gcaactttga aacgttaaaa atggtgggta ttcgattttt ctctcgtttt tgtcaattcg
    18301 attgtccaca gttatggtca cgcccgtcac caacggctta ccggatcgtt tcacagtaag
    18361 ccctacgatg aaatgtgaca aaaattgact ttattcagca aaaatgaaaa tcagcccgct
    18421 gaatatgtaa cattaattaa cccgaacaat acgggcaaaa aacattcatg ataaaaatat
    18481 ttattggtca ttatattaac gtattttata gcactgccga tatcacgctc aaaaaacaac
    18541 cactgctatt tttagcaaag cttatggtat actccgccgc cttaacattt ttcaccgcaa
    18601 attttcattg caacatgacg aggaaaataa atgagtacgc ctgatttttc tactgccgag
    18661 aataatcaag aactggcaaa tgaagtctcc tgcctgaaag cgatgctgac gctgatgctg
    18721 caggcgatgg gacaagctga cgcgggccgc gtgatgttaa agatggaaaa acagcttgcg
    18781 ctgatcgaag acgaaaccca ggctgcagta ttttccaaaa cggttaagca aattaaacaa
    18841 gcctaccgtc agtaatataa aaccggctga gagcgtgcct ttcagccggt ttttgcatct
    18901 ggcacgcaga aagaaaagcg atcaaattaa gccagtagcg gccgcgtaac aggccacctg
    18961 ggtcttattt ggtgcattga tttttttctg catgtttttc tgatggaaat tgaccgtatt
    19021 ctcagagatt gacaaaatca tcgctatctc tgctgatgtc ttcccttccg ccgtccattt
    19081 cagaatttct ttttcgcgct tgctgaaatt catctctggc gtcatcacta tttcatcatt
    19141 taaacgcatc agagccatca gactttcgcg caccagtaac tgcattttta attgcagttc
    19201 atcactaaga atgggtattt cgcgcgtgct gcaacgggaa aaggacaaaa agcccagcgc
    19261 ccgatttggc agcattaaat actgagtgac accgcggcgt aaaccatgtg cgcgcgcggc
    19321 ttcccataac ggctgtgctt cgctgaataa gtcatcattc cacattaaat ggccctgact
    19381 aaagttttca gggttcagca ccggatcaat tgcgagaaag ttttttgcct gataataact
    19441 aacccacgcc tcagggtaat tggtgtagaa agccacttta ggtcgcgtga atggtaccgg
    19501 gtggcgaaca cataacgaat agtaatcgta ctccagctgc tgagcctgaa gctctatttc
    19561 atggtagacc tcttctgcgg cctccatcct ctgaaaacgc aacagcatcg tgcgacgcca
    19621 gctgaaaaaa tccgtatcct gcatagtaaa ccgcaacgcc cctgagagtg agtatcattt
    19681 ataatgataa ttcaaactat cacataaata agatttatat ataatttata ttattcaggc
    19741 aatgaattac ttttgcaagc catcgcattc tcttatgtta ttaatgagtt atgctgattt
    19801 gttaagcagt tttatcacgc ttgaaatggc gtcccgcccc gacaggtgaa tcgtcggggc
    19861 tgattttttc ttattattgc agcagaaact tctcgaggaa ctggcgggtg cgaggctgct
    19921 ggggatcggc aaataacgct tttgctgccc cctgctcgac tatccgcccc tggtccataa
    19981 agatcgcccg gtccgcaaca tcccgggcaa agctcatttc gtgtgtcaca atcaccatcg
    20041 tgcgcttttc ctgcgccagc tggcggatgg tgttcaggac ttcgcccacc agctctggat
    20101 ccagcgccga cgttggctcg tcaaacaaaa tcacctcagg acgcattgcc agtgcacgcg
    20161 caatcgcaac acgctgctgt tgaccgccag acaaacgacg tggatagctg gtttctttac
    20221 cggccagccc aactttcgcc agcagctcgc gagcgcgcgc cgtggcctct tctttcggtt
    20281 cgcctttgac gatcaccggc ccttcaataa tgttttccag caccgtacga tgcggaaaca
    20341 aattaaagtt ctggaagaca aacccgacgt gctgacgcaa ctggcgaatc agcgattttt
    20401 gctgacttaa tgaacgtgca gtatcaatag tgatatcgcc aacggtgatc gttcccgctt
    20461 ccggttgttc cagcagattt atgctgcgta gcaacgtggt tttgccggaa ccactcggac
    20521 cgataattgc caccacttcg ccaggcttta cctcgaggtc gataccgtgc agcaccgtct
    20581 gaccgtgaaa ttttttcacc aggttcttaa cttcaatggc actcattttg gttctctctc
    20641 ctggcgatta agttgattct caaaatggtt ctgcaacgtc gataatactg tcgccatgat
    20701 ccagtagatg agcgaagccg ccaggtacat ggtgaacacc tccagcgtgc gcgaggtaat
    20761 caactgcgcc tgacggaaca gctccggcac ctggattgtc gcggccagcg acgtatcttt
    20821 taccagactg ataaagctgt tcgacagcgg cggcaacgcc acccgcgccg cctgtggcaa
    20881 aatcgcgcga cgcatggtct gccacggcgt cataccaata ctggcagcgg cttcccactg
    20941 acctttatca atagaagaaa tggcggcgcg cagcgtttcg gcggcatagg cggcagtgtt
    21001 cagcgacaga ccaatcattg ctgacggaat gggatctaat tcgataccaa actgcggcag
    21061 gccgtaatag atcataaaca gttgtgcgat gagcggcgta ccacgaaaaa tagagatata
    21121 aaaacgcgcc agccagcgca cgggccagat tggcgacagg cgcatcagcg cgagaataaa
    21181 cccgagtagt aagccaaaaa acatgccgcc gatactgagt tgcagggtat actcagcccc
    21241 tttcaacagg aacggcaagg aatcaataac cagttgtata ctttcttgca tgagcgttcc
    21301 cggagctaaa cgtggggatg ataggcgaac agcgcaggcg cgccgccggt atgaataaac
    21361 agaatcggcc cttcatcttt gaagcgtttc tgactgatac cgtcaatcag ccccgccatc
    21421 gcttttccgg tatacacagg atcaagcaga atgccttcca gacgcgccag caatttcact
    21481 gcttccatgc cttcgtcgtt cggcacgccg tagccaggtg caaaatagtc atcccagagt
    21541 aaaatttccg ctgatgcggt cagctccagt tctttcgcaa tcgcctgttg taggttaacc
    21601 actttcggca attgatcggc aacggaacgc gacacggtca cgccaatcag ttcgctttca
    21661 ggcatcaggt gttccagccc aacagccaat ccggcgtgag ttccggcact gcccgatgcg
    21721 accaccaccg acgaaatatt aaccgcccct tcacactgtt gcgcgatttc cagcgcactc
    21781 tccacataac ccagcgcgcc cagagcatta gaaccgccaa ccggaatgac atacgggcga
    21841 aagccttgtg cttcgactcg cgtcgccagc tcttccagtt gggcattggg atcggtcagt
    21901 gcgtcgcaca tttcaatctg ggtattgaac agatccagca acaaacgatt gccgttggtt
    21961 aaatagtttt ctgcggttgt gccaatagga ttttccagca gcgccacgca gtgcagaccg
    22021 agtttcgccg cgactgcggc agtctggcgc acatggttag actggatcgc gccggcagta
    22081 atcagcgtat cggcaccttc gcgcagggca tctgccgcga gaaattccag cttacgtaat
    22141 ttattgccgc ccattgccat gggtgtgacg tcatcccgtt tgatgaaaat ttcccgtcca
    22201 agataatcag aaaagcgcgg cagatattcg agcggcgttg gcgcgccgat aaactccaac
    22261 cgtggaaaac gggttaaatt atgcagtggc ataacagcct ccgatgtgtg ttgttgtgat
    22321 tttcttatta tgcacgctga aaacgcgtaa ataaaaaagg cgctagtgaa agcgcccttt
    22381 tttgtcatta tgctgattat ttggtcacat cagcaccaaa ccatttttcg gaaagagctt
    22441 gcagagtgcc gtctttttgc atttccgcaa ttgcatcatt caccgctttc agcaggtctt
    22501 catttccttt acgcagcgcc acgccagact cctgacggga gaatgcttca ccggttactg
    22561 ccagcgtatc gttggttttc ttcaccagat ccagcgccgc cagacgatca acgaggatcg
    22621 catcgatacg gcctacgcgc agatcctgat atttggtcgg gtcatcatca taggtacgca
    22681 catcgacgcc ctgaacattc tgccgcagcc actcttcata gttggtgccc agaccgacac
    22741 ccactttttt gcctttcaga tcagcagccg ttttaatggt gccttcgtta ccttttttca
    22801 ccagcgcctg aataccggaa atggtgtaag gggtagagaa atcgtatttt ttcttgcgct
    22861 cgtcagaaat ggtgacctga ttaatcacca catcaatgcg tttagagtcc agcgacgcca
    22921 gcataccgtc ccatttggtc ggttttagtg acgcctcaac gccaagatgt tttgccagct
    22981 gttgggcaaa ttccacttca aaaccggtta atttgccgtc atctccctga aaactgaacg
    23041 gcggataagt gccttccagc cctaccagca gcgtgccgcg ctctttaact ttattaagca
    23101 gaccttcatc tgcaaaactt ttaacgctca tgcccgcaac cagcgctacg gccatcacac
    23161 ccatcaatgc ctgacgtccc agatgtgcta atttcatatt taccccgaat gttgttatgt
    23221 ctgtttgcag tgtagagcca ttgtttgtaa acacaaaaac aactccgcta catcttattc
    23281 ttatttaata tatatcagaa gcaggcaggc tggaggattt ctgcacaagt ccggtacacg
    23341 tttgacgctg atagtgttga tacttccgta atgcgatgcg gtaattgttg gtgctggtgg
    23401 tgggcagcca cggggcgagg atttcatcaa ggaaaccgtc ctgcagcgga tcgagggaaa
    23461 tattttgctc gtgtagatga ttccccaaac ggcgcagacg aacgacatat tcacgcgccg
    23521 taccagggct catttcagtt tgctcaaaaa gaaattgctt aaagccgata atatcgaaaa
    23581 aatcactctg cgttttgcaa tgtaaatcac cgcagaatcg gcacaatgcc gcccatgatt
    23641 tttgttccac ttgccagcca ttttcatcaa gcagcatgtc caggcgggaa atctcgattt
    23701 tattcactat tttgccgtcg cgaacgaggg taatgcggtc gagtaattta cggcaatgcg
    23761 cgcaatgggt ctggctgtgt ttaaagtctt taagatagcg gcttaatggc cgtcttttca
    23821 ggtgctgcac catcattaag aactcctggt agtcaaaatt aaagtgcggc atttactgac
    23881 gttataactt acccagttta gtgcgtaacc gtttaatggc ctggctgtgt aactgactga
    23941 cccgcgattc cccgacctcc agcaccgcgc caatctcttt gagattcagc tcttcctggt
    24001 aatagagggt taataccagt ttttcgcgct ccggcaacgt ttcgatggct tccatcaccc
    24061 gctggcgcag attactgtcc agcagttgtt gtagcgggtt ttctcgctga tgatcatcag
    24121 taaccagttc gatgctatcg ccgtgctctt cgcgccactc atcgtaggag aagagctggc
    24181 tgttattggt gtcgagcaac atttggcgat aatcggcaat atcgatccct aaacgttccg
    24241 ctacctcagt ttccgtggcg ttgcggccaa gttcctgctc cagttgccct attgcctgtg
    24301 ccacttcacg cgcgttgcgt cgcacgctgc gcggcaccca gtcacggctg cgaagttcat
    24361 ccagcatagc gccacggata cgctgcactg cgtaagttgt aaatgccgtt ccttgtaggg
    24421 cgtcatagcg ttcgacggca ttaagtaacc caatgccgcc cgcctgtagc agatcgtcaa
    24481 gttccacgct cgcgggcagt cgaacctgca ggcgcaatgc ttcgtgacgc accagcggga
    24541 cataacgctg ccacagcgag tgtttatcca ttacaccttc agcggtatag agtgaattca
    24601 cgataaacag ccctgcgtta tatgagttat cggcatgatt atccgtttct gcagggtttt
    24661 taatcggacg attagtgggt gaaatgaggg gttatttggg ggttaccggt aaattccatg
    24721 cagaaaaaac cccgccggtg gcggggtttg agcgataagt gtaaattaac gcagcagaga
    24781 cagtacgttc tgcgtggtct ggttagcctg tgccagaaca gaagtacctg cttgttgcag
    24841 gatctgcgca cgagacatgt tagacacttc ggtcgcgtag tcagcatctt cgatacggct
    24901 acgggcagaa gacaggttgt ttacggtgtt gccaaggttg gtgatggcag agtcgaaacg
    24961 attttgaatt gcacctaggt tagaacgcaa cgagtcaacc tgagacagtg ctttatcgat
    25021 agcagccaaa ggatcttctg ttttctgcgt agaaattgct gcaatagaat cagttttcag
    25081 gctcttacct tgtaaatcac taacactgta agttttgcca tcggttgcag ttacaacttc
    25141 ggttttgcca tcgcttccac ccagttcaac tttaacattg tcgtgtttga caccgtcagc
    25201 atcagtgtaa gacattgttt taacggaaac tgctcctgtt ttctgatcaa cattcgctgc
    25261 atactgttta ccgtcatcac caatcaacgc aaatgaacca gtatctttgc cattggcgtc
    25321 ttctaactta aagagttttg cacctgtgat agaagcggtt gcggtatcag tacccaactg
    25381 aacatcaata gcccccttcc ctttcaccgt tgtgacttcc tttaaattac cagcttgagg
    25441 ctgggtaccc gctagagccc ccagcttcag cttacctgca tcaggagatg tcggatcatc
    25501 ctccacagta acttcataat aaccattttc agcgggttta tctgaaccgg caactttaac
    25561 gtacaactta ccgttagcat cagacataat attaccgtca cgttggcccg gagtcgtagt
    25621 gcctttaact gtagctgtaa tatctgcatc aagtgtatta gcgtcagcaa gcttaactgt
    25681 cgatccaaaa taggttgttt cagccgttgc ggcttttaat ttagtaggat ctttaatacc
    25741 aaaaccagat aatcccagtg tgtcggaatt aatttcctgc agtttaatag taattgtttc
    25801 gccgtcgttt gcaccaacct gaatagtcat atcctgatca gaagccagca ctttaacgcc
    25861 gttaaactga gtctgaccag aaacacggtc aatttcactc agacgctgct ggatttcgga
    25921 ctggatggag gtcaggtcac tgtcagagtt agtaccgtta gttgcctgaa cagaaagttc
    25981 acgaatacgc tgcaggttgt tgttaatttc attcagcgca ccttcagtgg tctgcgcaac
    26041 agaaatacca tcattcgcgt tacgggaagc ctgagtcaga cctttaatat ttgctgtaaa
    26101 acggttagca atcgcctgac ctgctgcgtc atctttagca ctgttaatac gcaggccaga
    26161 agagagacgt tcaatggcgg agctcagaga agactgagat ttgttcaggt tattctgggt
    26221 caacagcgac aggctgtttg tattaatgac ttgtgccatg atcttttcct tatcaattac
    26281 aacttgatgt tattgggctg ttgcccacgg tttctcaccg taccccttgt atcggcacct
    26341 gaatttcgaa ctttagaaaa ttttagtttc tctcctgttt tttcttaacg gctgaaatat
    26401 ccgtaatata caactctact ctgcgcatca tcttcgtgaa tcaactatta aactttgcgc
    26461 acaaattgcc gataacccgc ttatctactg tttgcaatca aaaggaatta ggtatggctt
    26521 catttacatc tcttggcgtt ggttcgaatc tgccgctgga tacattgcta aacaacctga
    26581 ccatcgctga aaaaaaacgc ttaaacccaa ttactcagca acagagtgac aataccgcac
    26641 gtctgacagc ctatggcaca ttaaaaagtg cattagaaaa attccagact gcaaatactg
    26701 cgttaaataa agccgatctg ttcaaaagca ctaccgttac cagtagcaat gaagacctta
    26761 aagtttccac cgaagcaggt gctgctcccg gtatctatac catcagcgta acccaactgg
    26821 cgcaggcgca atctttacga actgattccc cgacaatcat tgcatcaaca aaagatgcac
    26881 tgggtgatga gtcatcagat acacgcacaa taaaaattac ccaagacggt cgtaaagagc
    26941 cgctggaaat caagctcaat aaagatcaga cgtcattgga tgagatcagc aaagccatta
    27001 acgatgccga tagtggaatt tccgctagta tcgttaaagt caaagatggt aactatcaat
    27061 tggtattgac cgccagtgaa ggtctggcca ataaaatgac catatctgtt gagggtgaca
    27121 gtaaattaaa tgatctgctg gcttatgaca gcaagaccaa caccgggaat atgaaggaac
    27181 tggttaacgc gcaaaatgca cagctaaacg ttaacggtat cgatattgaa cgttcaagta
    27241 acaaaattac cgatgctcct cagggagtga ctctcgattt gaccaaaaaa gtcactgacg
    27301 tccgggtcac ggtgacaaaa agcaacgata aagcaaccga agcaattaaa ggctgggtgg
    27361 attcatataa ctccctcatt gacaccttta acaccctgac aaaatataaa gaagtagacc
    27421 caggtgctga agcacaagat aaaaataatg gtgcacttct cggagacagc gttgtacgta
    27481 caattcaaag cggcatccgc gcacaatttg caaacggtgc cagcgacggt gccttcaaaa
    27541 cattaaacga gatcgggatt aagcaggacg gcacgacggg taagctgaaa attgatgatg
    27601 ataaactcaa aaaagtcctg aatgaaaata cagcatccgt acgtgaattg ctggtaggcg
    27661 atggtaaaga aacaggaatt accaccaaaa ttgccaccga ggtaaaaggt taccttgccg
    27721 atgatggcat tattgatagc gcacaggaca gtattaacgc cacactgaaa aaactgacca
    27781 aacagtatct atccgtcagt gccagcattg atgacaccgt ggcgcgttac actgcacagt
    27841 ttacgcaatt agataccatg atgagcaaac tgaataacac cagtacctat ctcagccaac
    27901 aatttactgc aatgagtaat tcctgatcac ggaggtcagc atgtataccg cgagcggctc
    27961 aaaagcctat gcacaaattg gcgtcgaaag cgccgtaatg agcgccagcc agcagcagct
    28021 ggtcaccatg ctatttgatg gagtgctgag cgcactggtt agagcgcgcc tgtttatgca
    28081 ggacaacaat cagcaaggca aaggcgtctc tttgtcaaaa gcgatcaaca tcattgagaa
    28141 cggacttcgg gtgagtcttg atgaagagag caaagacgaa ttaacccaaa acttgattgc
    28201 tctttatagc tatatggtca ggcgcttgct gcaagccaat ttacgcaacg atgtctccgc
    28261 agtcgaagaa gtggaagcat taatgcgtaa tattgccgat gcctggaaag agtcgttact
    28321 ctccccttct ttgattcagg acccagtctg atgaaccatg caccgcattt gtatttcgcc
    28381 tggcaacaac tcgtcgaaaa aagccagctc atgttacgcc tggcaacgga agaacaatgg
    28441 gacgaactca tcgccagcga aatggcgtat gtgaatgcgg tgcaggagat agcacacctg
    28501 actgaagagg ttgccccgtc caccacgatg caggagcagc tccgcccgat gctgcgcctg
    28561 attctcgaca acgaaagcaa ggtaaagcag ttattacaga ttcgtatgga tgaactggcg
    28621 aaactggtcg gtcagtcatc ggtgcaaaaa tcggtgttaa gtgcctatgg cgatcagggc
    28681 ggctttgtgc tggctccgca agataacttc tcgtgaatct taacgagcta atggttcgcg
    28741 aataatccga ttacggctac gcttctaatg ttccccttga atggagtcga agaatgcgta
    28801 atcccacgct gttacaatgt tttcactggt attacccgga aggcggtaag ctctggcctg
    28861 aactggccga gcgcgccgac ggttttaatg atattggtat caatatggtc tggttgccgc
    28921 ccgcctataa aggcgcatcg ggcgggtatt cggtcggcta cgactcctat gatttatttg
    28981 atttaggcga gtttgatcag aaaggcagca tccctactaa atatggcgat aaagcacaac
    29041 tgctggccgc cattgacgcc ctgaaacgta atgacattgc ggtgctgttg gacgtggtag
    29101 tcaaccacaa aatgggcgcg gatgaaaaag aagctattcg cgtgcagcgt gtaaatgctg
    29161 atgaccgtac gcaaattgac gaagaaatca ttgagtgtga aggctggacg cgttacacct
    29221 tccccgcgcg tgccgggcaa tactcgaagt ttatctggga tttcaaatgt tttagcggta
    29281 tcgaccatat cgaaaaccct gatgaagatg gcatatttaa aattgttaac gactacaccg
    29341 gcgaaggctg gaacgatcag gttgatgatg aattaggtaa tttcgattat ctgatgggcg
    29401 agaatatcga ttttcgcaat catgccgtga cggaagagat taaatactgg gcgcgctggg
    29461 tgatggaaca aacgcaatgc gacggttttc gtcttgatgc ggtcaaacat attccggcgt
    29521 ggttttataa agagtggatc gaacacgtac aggaagttgc gccaaagccg ctgtttattg
    29581 tggcggagta ctggtcgcat gaagtcgata aactgcaaac gtatattgat caggtggaag
    29641 gcaaaaccat gctgttcgat gcgccgctgc agatgaaatt ccatgaagca tcgcgcatgg
    29701 ggcgtgacta cgacatgacg cagattttca cgggtacatt agtggaagcc gatcctttcc
    29761 acgccgtgac gctcgttgcc aatcacgaca cccaaccgtt gcaagccctc gaagcgccgg
    29821 tcgaaccgtg gtttaaaccg ctggcatatg ccttaatttt gttgcgggaa aatggcgttc
    29881 cttcggtatt ctatccggac ctctacggtg cgcattacga agatgtcggc ggtgacgggc
    29941 aaacctatcc gatagatatg ccaataatcg aacagcttga tgagttaatt ctcgcccgtc
    30001 agcgtttcgc ccacggtgta cagacgttat ttttcgacca tccgaactgc attgccttta
    30061 gccgcagtgg cactgacgaa tatcccggct gcgtggtggt catgtcgaac ggggatgatg
    30121 gcgaaaaaac cattaatctg ggagagaatt acggcaataa aacctggcgt gattttctgg
    30181 ggaaccggca agagagcgta gtaaccgacg aaaacggtga agcgaccttc ttttgcaacg
    30241 gcggcagcgt cagcgtgtgg gttatcgaag aggtgattta aattcatccc cggcggcaag
    30301 ccggggagat ttcattacgg cagtggcgtc ggtaacggcg ctttatccag cgcggcggca
    30361 cactctgccg tcgggcgatc cacacgctcc atcgtcatac catcgtactc aatggtgtta
    30421 ccgtcacgct caacctcgta cagctcacgt tttacggtaa cgttagtgag atcatcagac
    30481 atcaatgtca acttgcccgg cacggcaatc acccgctgcc actgacggca atccagggta
    30541 tcgccctctt tagtgacaat caggctgcct atcgcttccg gactgaccag cgcacgttgc
    30601 ggccctttgg tctgccagta gcccgccagc cagtccggcg cgggggtttt cacgacattg
    30661 ttatagtttt cgacttcggc acagcccgcc agcaacatga gcgcgcctgc aattgcgagt
    30721 tttttcatca ttcgtcctgc atgagaagaa aagaggattg tggcattaaa gccctgatgt
    30781 cgccagcctt tccaggttca gagagaaatt tgatctaact attatttttg tgaattatta
    30841 ccccgaaaat aaatttgcat gatgtatgat tcgcgattct tgtttcaaac cttctgagtt
    30901 cagaggctac attcatgtca tggcagcaat tcaaacacgc ctggttgatt aaattctggg
    30961 cacccatccc tgcggtcatc gcggcgggta ttctctccac ttactatttt ggcattactg
    31021 gcaccttttg ggctgtcacg ggtgaattta cccgttgggg cggtcagctc ctgcagctgt
    31081 ttggcgtcca tgctgaagag tggggttatt ttaaaattat ccatctggaa ggatcgccat
    31141 taacccgcat cgacgggatg atgatcctcg gcatgtttgg cggctgcttt gccgcagcgc
    31201 tgtgggccaa caatgtcaaa ctgcgcatgc cacgcagccg tatccgcatt atgcaggcca
    31261 ttattggcgg tattatcgct ggttttggcg cgcgtctggc aatgggctgt aacctggcgg
    31321 cgttctttac cggtattcct cagttctcgc tgcatgcctg gttctttgcc atcgccactg
    31381 ccattggttc atggtttggc gcacgcttta ccctgctgcc catcttccgt attcccgtga
    31441 aaatgcagaa agtttctgcc gcctcaccgc tgacgcaaaa accggatcag gcgcggcgtc
    31501 gttttcgtct cgggatgctg gtctttttcg gtatgctggg ctgggcgctg ctcacggcga
    31561 tgaaccaacc aaaactgggg ctggcaatgc tgtttggcgt cggctttggt ttactgattg
    31621 aacgtgcgca aatctgcttt acttcggcgt tccgcgatat gtggatcacc ggacgtaccc
    31681 atatggcgaa agcaatcatt atcggtatgg cggtgagtgc catcgggatc ttcagttacg
    31741 tacagttagg cgttgaaccc aaaatcatgt gggcgggacc aaacgcggta attggtggtt
    31801 tactgtttgg ttttggcatc gtgctggcag gcggctgcga aaccggttgg atgtaccgcg
    31861 cggtagaagg tcaggtgcac tactggtggg tcggtctggg caatgtgatc ggctcaacca
    31921 ttctggcgta ttactgggat gatttcgctc cggcgctggc caccgactgg gacaaaatca
    31981 acctgctgaa aacctttggc ccgatgggtg gcctgctggt gacatatttg ctgttgttta
    32041 ctgcgctgat gttgattatc ggctgggaaa aacgcttctt ccgccgtgcg gcaccgcaga
    32101 ctgctaagga gatcgcatga aaaatatcat tcctgattac cgtcttgata tggtgggtga
    32161 accctgccct tatccggcag tcgcaaccct tgaggcgatg ccgcagttaa aaaaaggtga
    32221 gatcctggaa gtggtgagcg actgtccgca gtcgatcaat aatattccac tggatgctcg
    32281 taatcacggc tatacggtgc tggatattca gcaagacggg ccgaccattc gttatttaat
    32341 tcagaagtaa tccctcattc ccgctgtggc caacagcggg aatatcgttg cctctgtacc
    32401 acatagattt tacccgcccc ctctcctatt cttttcagtg tgctctcagg aggttgctat
    32461 gtgtggacgc tttgcccaat cccaaacgcg tgaagattac cttgcgcttc tcgcggaaga
    32521 tattgaacgc gatattccct atgatcccga acccattggc agatacaacg tcgcgccggg
    32581 aaccaaagtt cttctgctca gtgaacgtga tgaacacctt catctggatc cggttttctg
    32641 gggatatgct cccggatggt gggataaacc gccgctgatt aacgcccgcg tagaaactgc
    32701 ggccaccagt cgtatgttta aaccgctctg gcaacatggt cgggcaatct gttttgccga
    32761 tggctggttt gagtggaaaa aagaaggcga caaaaaacag ccttatttta tctatcgtgc
    32821 tgacggacaa cctgttttta tggccgcgat aggtagcaca ccgtttgagc gcggtgacga
    32881 agccgaagga tttttaattg tcactgcagc agcagaccag ggtctggtag atattcatga
    32941 ccgccgcccg ctggtactgt cgccagaagc tgcgcgggaa tggatgcggc aagagattgg
    33001 cggtaaagaa gcatcagaaa ttgctaccaa cggctgtgtg ccagcaaacc agttcacctg
    33061 gcacccggta tcgcgcgcgg taggtaatgt caaaaaccag ggcgcggagt taattcaacc
    33121 ggtttgataa gccaggagac tattgatcaa taatactgcg tcataagaaa tctctattag
    33181 acaaagtaga cgctccttcc acatgcgcca caagaaacct ctattccagt gacacaatta
    33241 cgcctgatta tttccctagc ccggaatatg aataaaaaca tcaacaaaga ttaaattatt
    33301 caaacgttac tgttgcgtct gcggtcgtaa caacatccga cgtggtgatg tgtatcaaat
    33361 gaggcctctg atgatcagag ggtttattgc gtatacggat cgtggatggc agaaaacttt
    33421 caggatcagg tatccatttt aaaccagaaa tagggtgagt ttgccccatc catgccccac
    33481 gcgggcagat gggatgtaat taacaacagg ttacaaaacc tacacttgca tggacatcac
    33541 ttcctgatac gccgccacca gcttattacg cacctgaatc cccatttgca tagaaactga
    33601 ggctttttgc atatcggtca tcacatcgtt taacgccacg ccgggttcac cgagggtgaa
    33661 tttttctgcc tgcgtgcggg cagctgtttg tgtatcgcta atgcgatcga gcgcggcgtg
    33721 cagctgcccg gcaaaactaa tggtcggttg cggcagtgaa tcctgcgcgc gcgcactcat
    33781 cgccgtagcc tgtaactggc tgataacccc ttcaatcccc tgtatcgctg acattttcat
    33841 ctcctggata atttctggta gcaaagccta ccagtaagtc aataagacaa aggcgctaaa
    33901 tagcaacaaa aaaacgggtt tattggcgga tagaaaaaaa cgaaagcaca aataatggga
    33961 gcgtcaattt ttcgagtttg ctgacccggg agtgagtctt gttccacttt gccaataacg
    34021 ccgtccataa tcagccacga ggtgcgcgat gaatgcgact gcagcccaga caaaatctct
    34081 tgagtggctt aatcgcctgc gtgcgaatcc gaaaattcca ttgattgttg ccggttccgc
    34141 ggcagtggcg gtcatggtcg cactgatcct gtgggcgaaa gcccccgact accgcacatt
    34201 attcagcaat ctttccgatc aggatggtgg cgcaattgtc agccaactga cgcaaatgaa
    34261 tattccttac cgcttcagcg aagccagcgg cgctattgaa gttccggcag ataaagttca
    34321 cgaactgcgt ctgcgcctgg cacaacaagg tttgcccaaa ggcggcgcgg tcggtttcga
    34381 actactcgat caggaaaagt ttggtatcag ccagttcagc gaacaggtga attatcagcg
    34441 ggcgctggaa ggcgagcttt ctcgtaccat cgcaactatc ggcccggtaa aaggggcgcg
    34501 cgtacatctg gcaatgccga aaccgtcttt attcgtccgt gaacaaaaat ccccttctgc
    34561 atcggtgacg gtaaatctgt tacccggccg cgcactcgat gaagggcaaa ttagcgccat
    34621 tgtgcatctg gtttccagcg ccgttgctgg tctgccgccg ggaaacgtca cgctggtgga
    34681 tcagggcgga catctgttaa cccagtccaa taccagcggg cgcgatctta atgatgctca
    34741 gttgaaatat gccagcgatg tcgaaggccg tattcagcgg cgtattgaag caatcctgtc
    34801 gcctattgtt ggtaacggta atattcacgc ccaggtcacg gcgcagctgg acttcgccag
    34861 taaagaacaa acggaagaac agtatcgccc taacggtgat gaatctcatg cggcgcttcg
    34921 ttcacgccag cttaatgaga gcgagcaaag cggttccggt tatccgggcg gcgtaccggg
    34981 ggcgttgtcg aatcaaccgg cacctgcgaa taacgcgcca atcagcacgc ctccagcaaa
    35041 tcaaaataac cgccagcagc aggcgagcac caccagcaat agcgggccgc gtagcacaca
    35101 gcggaatgaa accagtaact acgaagtcga tcgcaccatt cgtcatacca aaatgaacgt
    35161 gggcgatgtg caacgtctgt cagtcgcggt agtggtgaat tacaaaacct tgccagacgg
    35221 taaaccattg cctctcagca acgaacagat gatgcaaatt gaagatctga cccgcgaggc
    35281 gatgggcttt tctgaaaaac gcggtgactc gctcaatgtc gttaactcgc cgttcaatag
    35341 cagtgacgaa agcggcggag aactgccgtt ctggcaacag caagcgttta tcgatcagtt
    35401 gctggctgcc ggtcgctggt tgctggtact gctggtggcg tggctgctgt ggcggaaagc
    35461 ggtacgccag cagttaacac gtcgcgccga ggcgatgaaa gctgtacagc aacaggcgca
    35521 ggcccgtgag gaagtggaag atgcggtgga agtccgcctg agcaaagacg aacaactcca
    35581 acaacgacgc gctaaccaac gtctgggggc agaagtcatg agccagcgta tccgtgaaat
    35641 gtctgataac gatccgcgcg tggtggcgct ggtcattcgc cagtggataa ataacgatca
    35701 tgagtaacct gacaggcacc gataaaagcg tcatcctgct gatgaccatt ggcgaagacc
    35761 gggcggcaga ggtgttcaag cacctctccc agcgcgaagt gcaaaccctg agcgctgcaa
    35821 tggcgaacgt cacgcagatc tccaacaagc agctaaccga tgtgctggcg gagtttgagc
    35881 aagaagctga acagtttgcc gcactgaata tcaacgccaa cgattatctg cgttcggtat
    35941 tggtcaaagc tctgggtgag gaacgtgccg ccagcctgct ggaagatatt ctcgaaactc
    36001 gcgataccgc cagcggtatt gaaacgctca actttatgga gccgcagagt gccgccgatc
    36061 tgattcgcga tgagcatccg caaattatcg ccaccattct ggtgcatctg aagcgcgccc
    36121 aggccgccga tattctggcg ttgttcgatg aacgtctgcg ccacgacgtg atgttgcgta
    36181 tcgccacctt tggcggcgtg cagccagccg cgctggcgga actgaccgaa gtactgaatg
    36241 gcttgctcga cggtcagaat ctcaagcgca gcaaaatggg cggcgtgaga acggcagccg
    36301 aaattatcaa cctgatgaaa actcagcagg aagaagccgt tattaccgcc gtgcgcgaat
    36361 tcgacggcga gctggcgcaa aaaattatcg acgagatgtt cctgttcgaa aatctggtgg
    36421 atgtcgacga tcgcagcatt cagcgtctgt tgcaggaagt ggattccgaa tcgctgttga
    36481 tcgcgctgaa aggggccgag cagccactgc gcgagaaatt cctgcgcaat atgtcgcagc
    36541 gtgccgccga tattctgcgc gacgatctcg ccaaccgtgg tccggtgcgt ctgtcgcagg
    36601 tggaaaacga acagaaagcg attctgctga ttgtgcgccg ccttgccgaa actggcgaga
    36661 tggtaattgg cagcggcgag gatacctatg tctgataatc tgccgtggaa aacctggacg
    36721 ccggacgatc tcgcgccacc acaggcagag tttgtgccca tggtcgagcc ggaagaaacc
    36781 atcattgaag aggccgaacc cagccttgag cagcaactgg cgcaactgca aatgcaggcc
    36841 catgagcaag gttatcaggc ggggattgcc gaaggtcgcc agcaaggtca tgagcagggc
    36901 tatcaggaag gactggcccg ggggctggag caaggtctgg cagaggcgaa gtctcaacaa
    36961 gcgccaattc atgcccggat gcagcaactg gtcagcgaat ttcaaactac ccttgatgcg
    37021 cttgatagtg tgattgcttc gcgcctgatg cagatggcgc tggaggcggc acgtcaggtc
    37081 atcggtcaga cgccaacagt ggataactcg gcactgatca aacagatcca acagttgttg
    37141 cagcaagaac cgttattcag cggtaaacca cagctgcgcg tgcacccgga tgatctgcaa
    37201 cgtgtggatg atatgctcgg cgcaacctta agtttgcatg gctggcgctt gcggggcgat
    37261 cccacactcc atcctggcgg ctgtaaagtc tccgccgatg aaggcgatct cgacgccagt
    37321 gtcgccactc gctggcaaga actctgccgt ctggcagcac caggagtggt gtaatgacca
    37381 cgcgcctgac tcgctggcta accacgctgg ataactttga agccaaaatg gcgcagttgc
    37441 ctgcggtacg tcgctatggg cgattaaccc gcgctaccgg gctggtgctg gaagccaccg
    37501 gattacaatt gccgctcggc gcaacctgtg tcattgaacg ccagaacggc agcgaaacgc
    37561 acgaagtaga aagcgaagtc gttggcttta acggtcaacg gctgttttta atgccgctgg
    37621 aggaagtcga aggtgtcctg cccggcgcgc gggtttatgc caaaaacatt tcggctgaag
    37681 gactgcaaag cggcaagcag ttgccgctcg gtccggcgtt attaggtcgc gttctggacg
    37741 gcagcggtaa gccgctcgat ggcctgccct cccccgatac gacggaaacc ggtgcgctga
    37801 ttaccccgcc atttaacccg ttgcaacgta caccgattga acatgtgctg gacaccggcg
    37861 tgcgcccaat caatgccctg cttaccgttg ggcgtgggca gcgtatggga ctgtttgccg
    37921 ggtccggcgt tggtaaaagt gtgctgctgg ggatgatggc acgttacacc cgcgccgatg
    37981 tcattgtcgt gggtttgatt ggtgaacgcg gacgcgaagt aaaagatttt attgagaata
    38041 tcctcggtgc cgaagggcgt gcacgctccg tggtgattgc cgctccggcg gatgtttctc
    38101 ctctcctgcg aatgcagggt gccgcctatg ccacgcgcat tgccgaagat tttcgcgatc
    38161 gtggtcagca tgtgttgctg attatggact ccctcacccg ctacgcgatg gcccagcgtg
    38221 aaattgcgct ggcgattggc gaaccacccg ccactaaagg ttatcccccg tcggtgtttg
    38281 ccaaattacc ggcactggtc gagcgtgccg gaaatggcat tagcggcggc ggatcgatta
    38341 ctgcatttta taccgtgctc actgaaggcg atgaccagca ggaccccatt gccgactctg
    38401 cgcgggcaat cctcgacggt cacattgtgc tgtctcgccg actggcggaa gccgggcact
    38461 atccggctat cgatattgaa gcgtcgatca gccgcgcaat gacggcgttg atcagtgagc
    38521 aacattacgc gcgagtgcgc accttcaaac agctgttgtc gagttttcag cgtaaccgcg
    38581 atctggttag cgtcggcgcg tatgccaaag gcagcgatcc gatgctcgac aaagccatcg
    38641 ccctgtggcc gcagctggag ggctatttgc aacaaggcat ttttgaacgc gcggactggg
    38701 aagcgtctct ccaggggctg gagcgtattt tcccgacagt gtcataaccc aggagataac
    38761 ggcagatggc agaacatggc gcgctggcga ccctgaaaga tctggcagaa aaagaggtag
    38821 aggatgccgc gcgcctgctg ggtgaaatgc gtcgcgggtg tcagcaggcg gaagaacagc
    38881 tcaaaatgct gatcgattat cagaatgaat atcgcaataa cctcaacagc gatatgagtg
    38941 ccgggatgac cagcaaccgc tggatcaact atcagcagtt tatccagacg ctggaaaaag
    39001 ccattactca gcatcgccag caacttaatc agtggacgca gaaagttgac attgccctga
    39061 acagctggcg agaaaagaaa caacgtttgc aggcctggca gacactgcag gaacggcaat
    39121 ccacggcggc actgcttgca gaaaaccgcc tcgatcagaa aaagatggat gagttcgccc
    39181 agcgcgccgc catgaggaaa cctgaatgat tcgcttagcg cccttaatta ccgccgacgt
    39241 tgacaccacc acattgcctg gcggcaaagc cagcgatgct gcacaagatt ttctcgcgtt
    39301 gttgagcgaa gcattagcag gcgagacaac taccgacaaa gcggcccccc agttgctggt
    39361 ggcaacagat aagcccacga caaaaggcga gctgctgatc agcgatattg tttccgacgc
    39421 gcaacaagcg gatttactga tccctgtgga tgaaacactg cctgtcatca acgtcgaaca
    39481 atccacatca acaccgttaa ccaccgctca gacgatgacg ttggctgcgg tggctgacaa
    39541 aaatacgaca aaagacgaaa aagcggatga tctgaatgaa gacgtcaccg caagcctgag
    39601 cgcccttttt gcgatgttgc cgggttttga caatacgccc aaagtgactg atgtgccgtc
    39661 aaccgtgtta ccggcagaga aaccaacgct cttcacaaaa ctgacttctg cgcaactcac
    39721 aacagcacag cctgatgatg cccccggcac gccagctcag ccattaacac cgctggtagc
    39781 agaagcccag agtaaagcgg aagtcatcag cacaccgtca ccggtgaccg ctgccgccag
    39841 cccgctaatt actccacacc agacacagcc actgcccacc gtcgccgcgc ctgttttgag
    39901 tgcaccgctg ggttctcacg aatggcaaca atcattaagc cagcatattt cgctattcac
    39961 ccgccagggg caacaaagtg cagagttgcg tctgcacccg caggatttag gtgaagtgca
    40021 aatctccctc aaagtggatg ataaccaggc acaaatccag atggtttcac cgcatcagca
    40081 tgtacgcgcc gcgctggaag cagcgcttcc ggtactgcgt acgcagctgg ccgaaagtgg
    40141 cattcagtta gggcaaagca acatcagtgg cgaaagcttt agtggtcagc agcaggccgc
    40201 ttcccaacaa cagcaaagcc aacgcacagt aaaccatgaa cctctggcgg gggaagacga
    40261 cgatacgctt ccggttcccg tctctataca agggcgcgta acaggcaaca gcggcgttga
    40321 tattttcgcc taacgtcaga ggtagcaccg taatccgcgt cttttccccg ctttgttgcg
    40381 ctcaagacgc aggataatta gccgataagc agtagcgaca caggaagacc gcaacacatg
    40441 actgattacg cgataagcaa gaaaagcaag cgatcgcttt ggatcccgat tctggtattc
    40501 attaccctcg cggcctgtgc cagcgcaggt tacagctact ggcattcgca tcaggttgcc
    40561 gctgacgaca aagcgcagca acgcgtcgta ccctccccgg tcttctacgc gctggatacc
    40621 ttcacggtca atctgggcga tgcggatcgc gtgctttata tcggcgtaac cctgcgcctg
    40681 aaagatgaag ctacccgctc gcggctgagt gagtatttgc cggaagtccg tagccgtttg
    40741 ctgttactgt tttcgcgtca ggatgctgcc gtactggcga cagaagaagg caagaaaaac
    40801 ctgattgccg agattaaaac cacgctttcc accccgcttg ttgccgggca accgaaacag
    40861 gatgtcaccg acgtgctgta taccgctttt attctgcgat aacgacatgg gcgatagtat
    40921 tctttctcaa gctgaaattg atgcgctgtt gaatggtgac agcgaagtca aagacgaacc
    40981 gacagccagt gttagcggcg aaagtgacat tcgtccgtac gatccgaata cccaacgacg
    41041 ggttgtgcgc gaacgtttgc aggcgctgga aatcattaat gagcgctttg cccgccattt
    41101 tcgtatgggg ctgttcaacc tgctgcgtcg tagcccggat ataaccgtcg gggccatccg
    41161 cattcagccg taccatgaat ttgcccgcaa cctgccggtg ccgaccaacc tgaaccttat
    41221 ccatctgaaa ccgctgcgcg gcactgggct ggtggtgttc tcaccgagtc tggtgtttat
    41281 cgccgtggat aacctgtttg gcggcgatgg acgcttcccg accaaagtgg aaggtcgcga
    41341 gtttacccat accgaacagc gcgtcatcaa ccgaatgttg aaactggcgc ttgaaggcta
    41401 tagcgacgca tggaaggcga ttaatccgct ggaagttgag tacgtgcgtt cggaaatgca
    41461 ggtgaaattt accaatatca ccacctcgcc gaacgacatt gtggttaaca cgccgttcca
    41521 tgtggagatt ggcaacctga ccggcgaatt taatatctgc ctgccattca gcatgatcga
    41581 gccgctacgg gaattgttgg ttaacccgcc gctggaaaac tcgcgtaatg aagatcagaa
    41641 ctggcgcgat aacctggtgc gccaggtgca gcattcacag ctggagctgg tcgccaactt
    41701 tgccgatatc tcgctacgcc tgtcgcagat tttaaaactg aaacccggcg acgtcctgcc
    41761 gatagaaaaa cccgatcgca tcatcgccca tgttgacggc gtcccggtgc tgaccagtca
    41821 gtacggcact ctcaacggtc aatatgcgtt acggatagaa catttgatta acccgatttt
    41881 aaattctctg aacgaggaac agcccaaatg agtgacatga ataatccggc cgatgacaac
    41941 aacggcgcaa tggacgatct gtgggctgaa gcgttgagcg aacaaaaatc aaccagcagc
    42001 aaaagcgctg ccgacgcggt gttccagcaa tttggcggtg gtgatgtcag cggaacgttg
    42061 caggatatcg acctgataat ggatattccg gtcaagctga ccgtcaagct gggccgcaca
    42121 cgaatgacca tcaaagagct gttgcgtctg acgcaagggt ccgtcgtggc gctggacggt
    42181 ctggcgggcg aaccactgga tattctgatc aacggttatt taattgccca gggcgaagtg
    42241 gtggtcgttg ccgataaata tggcgtgcgg atcaccgata tcattactcc gtctgagcga
    42301 atgcgccgcc tgagccgtta gtgatgaata accacgctac tgtgcaatct tccgcgccgg
    42361 tttctgctgc gccactgctg caggtgagcg gcgcactcat cgccattatt gccctgatcc
    42421 tcgctgctgc ctggctggta aaacggttgg gatttgtccc taaacgcact ggcgttaacg
    42481 gtctgaaaat tagcgccagt gcttcgctgg gcgcgcgtga acgggttgtg gtggtcgatg
    42541 tggaagatgc acggctggtg ctcggcgtta ccgcagggca aatcaatctg ctgcataaac
    42601 ttcccccttc agcaccaacg gaagagatac cgcagcccga ttttcagtcg gtcatgaaaa
    42661 acttgcttaa gcgtagcggg agatcctgat gcgtcgtttg ttgtctgtcg cccctgtcct
    42721 tctctggctg attacgcccc tcgccttcgc gcaactgccg ggtatcacca gccagccgct
    42781 gcctggcggt ggacaaagct ggtcgctccc ggtgcagacg ctggtgttca tcacctcgtt
    42841 gacgtttatt ccggcaattt tactgatgat gaccagtttc acccgcatca ttattgtttt
    42901 tggtttattg cgtaacgcgc tgggaacacc ctccgcgcca cctaaccagg tattgctggg
    42961 gttggcgctg tttttgacct tttttattat gtcgccggtg atcgacaaaa tttatgtcga
    43021 tgcgtaccag ccattcagcg aagagaaaat atcaatgcag gaggcgctgg aaaaaggggc
    43081 gcagccgctg cgtgagttta tgctgcgtca gacccgtgag gcggatttag ggttgtttgc
    43141 cagactggcg aatactggcc cgttgcaggg acctgaagcc gtgccgatgc gcattttgct
    43201 cccggcctac gtgaccagcg agttgaaaac cgcatttcag ataggcttca cgattttcat
    43261 cccttttttg attatcgacc tggtgattgc cagcgtgttg atggcattgg ggatgatgat
    43321 ggtccccccc gccaccattg ctctgccctt taaactgatg ctgtttgtac tggtggatgg
    43381 ctggcaattg ctggtcggtt cgctggcgca gagcttttac agctagagag gcaaaatgac
    43441 acctgaatcg gtcatgatga tggggactga agcgatgaaa gtcgcgctgg cactggctgc
    43501 cccgctgttg ctggtggcgc tggtcacggg ccttatcatc agtattttgc aggccgccac
    43561 gcagatcaac gaaatgacgc tgtcgtttat tccaaaaatc atcgccgtat ttattgccat
    43621 tattattgcc ggaccgtgga tgctcaatct gttgctggat tacgtccgca ccttgttcac
    43681 taacctgccg tatatcatcg ggtagcccgt acaatgatgc aggtgacaag cgatcaatgg
    43741 ctttcctggc taagtctgta cttctggccg ttactgcgcg tgctggcgct catttctacc
    43801 gcgccaattc tgagcgaacg cagcgtgccg aaacgggtaa aactgggtct ggcaatgatg
    43861 atcacgttcg ctattgcccc atcattacct gccaacgatg ttcctgtttt ttcgttcttt
    43921 gctctgtggc tggccgtgca gcagatcctg atcggcattg cgcttggttt caccatgcaa
    43981 tttgcctttg ccgctgtgcg aaccgctggc gaaattatcg gtctgcaaat ggggctgtca
    44041 tttgcgacgt ttgtcgatcc ggccagccat ctcaacatgc ccgttctagc gcgtatcatg
    44101 gatatgctgg cgttactgct gttcctgaca tttaacggtc atttatggtt gatttcactg
    44161 ctggtcgata cctttcacac cctgccgatt ggtggcgaac cgttgaacag caatgcgttt
    44221 ctggcactca ccaaagcagg gagtttgatt ttccttaacg ggctgatgct ggcgttaccg
    44281 ctcattactc tgctgctgac cctgaatctg gcattaggtt tactgaatcg tatggccccg
    44341 caattatcca tttttgttat tggatttcca ttaactctga ctgtcggtat ctctttaatg
    44401 gcggcattaa tgccgttaat tgcgcctttt tgcgaacatt tattcagtga gatgtttaat
    44461 ttgctggctg atattattag tgaattgcca ttaatataat tccgtaacgt ttatcatgtt
    44521 atcctaagga ttatccgaaa aataatacct acgaacatct tccaggatac tcctgcggcg
    44581 aaatatttgt tttaagctca ctcacatatc gcaacattta ctttacttta agacaattcc
    44641 aggcaaatta tacaacactt tacgggatag taagtccgcc tgaaaaatcg cgagagtggc
    44701 gcattaggtg acccatgttg ttccgtttag tcatgatgaa atattcaggt aaggggaatt
    44761 atcgttacgc attgagtgag ggtatgccat gtcaacgatt attatggatt tatgtagtta
    44821 cacccgacta ggtttaaccg gatatctgtt gagtagaggg gttaaaaaaa gagaaatcaa
    44881 cgacattgaa accgttgatg accttgccat agcttgtgat tcacagcgcc cttcagtggt
    44941 gtttattaat gaggactgtt tcatccatga tgcttctaac agtcagcaca tcaagcacat
    45001 cattaatcaa catcccaata cgttatttat cgtttttatg gcaattgcca atgttcattt
    45061 tgatgaatat ctattggtca gaaaaaattt attgataagt tctaaatcga ttaaaccgga
    45121 atctctcgac gatatccttg gcgatattct gaaaaaagag acaacgataa cctctttttt
    45181 aaatatgccg acgttatcat tgagccgaac cgaatcgagt atgttgcgaa tgtggatggc
    45241 aggtcaggga acgattcaaa tctctgacca aatgaatatc aaagccaaga ccgtttcatc
    45301 gcataaaggt aatattaaac gtaagatcaa aacgcataat aaacaggtta tctaccatgt
    45361 cgtccgactg acggataatg tgactaatgg tatttttgtc aacatgcgct aacacattct
    45421 gactggtggt ttcccaccag tcaggctgaa taagattact ctgctttctc cacaaagata
    45481 ccgtcctgat gccctgcttc attaaagaac cagatgccga gcgggtagtc ttccagcgaa
    45541 accaggtaca ttgtgccttc actaaactcc tcaactgcca gtaccacgcc aggacgacgc
    45601 ggaccgccat ccgttttgac tgttacccga tcattcacct tcatcgtttt cctcctgtgg
    45661 ctttgtgcca gtgtagaaca atttcgtttt tctggcagcg ccaggcgcgc gcgagtgctg
    45721 attttctcga cggtctatac ttaagagatg ccaggcggac ttaacgactg gcggcaacaa
    45781 cagagtaacg gttgcgagga aagatgatga aaaccgcaaa agagtacagc gataccgcaa
    45841 aacgtgaggt cagcgtcgat gtcgatgccc tgctggcggc gatcaatgaa attagcgaaa
    45901 gcgaagttca tcgcagccag aacgattctg aacacgttag cgtcgatgga cgtgaatatc
    45961 atacatggcg tgaattggcg gatgccttcg aactggatat tcatgacttc agcgtctctg
    46021 aagtgaatcg ttgaatgcac aataaaaaaa tcccgaccct gagggggtcg ggatgaaact
    46081 tgcttaagca agaagcactt aaaaaattcg ttacaccagg aaatctgatg tgttcatcac
    46141 cttatccgca atttttttcg ctgacaagaa aatattcgcg atatgaatga ttaacgctac
    46201 ttatgaatag aaatgtgacg tgcgtcaccc cttggtggct ctggcgtcaa cgggatcgct
    46261 cccgaaaaaa tcatctttga ttatttgtgc tgttttgaga atcatcctgg taaggggaga
    46321 actgcgcgac catgttttca attcaacaac cactactggt ttttagcgat cttgatggca
    46381 ccctgctgga cagtcatagt tatgactggc aaccagctgc cccctggctc agccgtttac
    46441 gcgaagcgaa tgttcccgtc attctctgta gcagtaagac atcagcggaa atgttgtact
    46501 tgcaaaaaac gttggggcta caaggtttac cgctgattgc cgaaaatggc gcagtgatcc
    46561 agcttgctga gcaatggcag gatatagacg gttttccacg catcatctca ggtattagcc
    46621 atggcgaaat cagccaggta ttaaatacgc tacgcgagaa ggaacatttt aaattcacga
    46681 cttttgatga tgtcgacgat gcaaccatcg ccgaatggac gggattaagc cgtagccagg
    46741 cggcgctgac gcagctgcat gaggcgtcgg taacgctaat ctggcgcgac agtgacgagc
    46801 gtatggcaca atttaccgct cgtctgaacg aactgggctt acagtttatg cagggtgcgc
    46861 gcttctggca cgtcctggat gcctctgccg gaaaagatca ggccgccaac tggattatcg
    46921 cgacctatca acaattatca ggcaaacgcc caaccacact tggcctgggc gatgggccaa
    46981 acgatgcgcc cttactggag gtaatggatt acgcggtgat tgtgaaaggg ctaaaccgtg
    47041 aaggggtgca tctgcatgat gaggatccga cccgcgtctg gcgaacgcag cgtgaaggac
    47101 cggaaggctg gcgtgaaggg ctggaccatt ttttctccgc tcgttaagcg ttatcgctcg
    47161 cgcatacccg attacgcccg gcctgtttag cgagataaag ccgacggtca gccagtgact
    47221 ggagttgttc aaaatcataa tcaccggttt cctcgctgct actaaccccc aacgaggcac
    47281 tgatgcgtat cgtcgtactc ttagcaatca acatctcttt ttcatttaac ttcaggcgaa
    47341 tacgttctgc gacttccgca gcctccgtca gactcgcgcc tggcagaatc acacaaaact
    47401 cctcaccacc gacccgcccg gcaacgtcct gcgcacgcaa ggaactgcta attaatccgg
    47461 cagcatgaga aagaacacgg tcgcccgcct gatgaccaaa gcggtcatta atcgctttaa
    47521 aatggtcaag atcgacctga atgacagaaa aaggatgttg gtgcgtctga cacaatttag
    47581 cgagcggacg ggctttttcg aacagtgcgc cacgattata taaacgggtt aaggtgtcgt
    47641 gccacgcctg ccactgcaac gagctttgca gaacatacat gttgctgacc atccggcgaa
    47701 tcacatacca ggagatgagt aacatggtgg taaagagcgc ccacagcagg gttaatgcaa
    47761 tgctgatact accgaaatcg ccgcgcacgc cttcgcttag cgtatggacg cgcaccagca
    47821 caccgtcgaa atggtccaga cgttcccagc taacatagcg actgtccata cgaatgccgc
    47881 cccgcgtgtc atgttccatc gcctgcgcca gcaaggccag ttcacgagga tcaaaaatat
    47941 tccctgttgg atggtcagga ttggaagagg tcaaaaatct cagcttactg tcatagagct
    48001 gatactcacc atcgaggttt ttatcgatgg cgtttcttaa aaattgctgc atagtacgca
    48061 caggaatact catccccagc acgccatacc agtagttatt actgtctacc ggaacactga
    48121 cggtaacctg cggttcagta ttgctggcgt gttccggttg cgaagtaaac cagcgtaccg
    48181 cgcggtgacg attttctcgt tgcgaatggc cgataaacca gggttgggtg acatagccgt
    48241 aataacgcgt tggaacattg cgcgtaaaca aggtcggctg cgtcgaaacg taaaatccgg
    48301 cacgcgagac atacatcgcc tgttcaacca tcgacgagga gttgtgcgcc agtcgcagca
    48361 agtaaccaac ttccagtgca gcggtaattt cattgtcgag gctttcattt tcgcgagaca
    48421 ggagattccc ctcgctgact aatgcatccg acacaccatt aaatggcaga gtgcgccgtc
    48481 ggttgagttc aatttgccag gcgtgctcgt cgcgatgctg ttcgaactcg gttacagcat
    48541 tacgcagaga ggtgaaatcc agtggcgcta cgagagcttc gcgcatgcca ttacgcaaaa
    48601 agatcagttt gtcgacgtta tactgcaaat gcttatcgag cgcgttggct acgttttcca
    48661 gatgattacg ctggctggag atataggcat cttccagcac cactacttca cgccaggtga
    48721 gcaaggtgga aaaaagcaat accacgataa agcagagatt aacgacatga ccaggcccca
    48781 ggcggcgtgc gagttttttc aaccagctct ggttttccat ttttgtctcg tgctgcaccc
    48841 tgacgactcc caacctgctt ttttatgatt ctggcataac ctggcgatag cgtaccgcaa
    48901 aacagcgata attttataat ggtggcatga taagacgcga ctatcattca ttgcaggcat
    48961 tggcacacca ggccggatgt gatccggcct ggtgttaatg ataccctttc aaacttcttc
    49021 cgcagaacga ctcccctccc ccggaacaag ctcggtttca tgaaaagctt cccgcttgac
    49081 cccgtaaccg tcataccaac gacactcaac cataccgctg gagtatccgg tgacaatcat
    49141 ccgcgggcca ccctctttaa ccgtaacttc ctcactaacc ataaagctca tactcgcctc
    49201 cttttttcga gtgaaacttg ttcaccttag ttgaagatgg cgaattttgc ataatagcct
    49261 gtgcgagtat taatgtgcct gaccgcgcat tttcgctacg gctttcactc ccagcaccac
    49321 gatgccgccg atgataaatc caagaatcag atttaaaaca gtcggtaata tcatcgccac
    49381 cactgcactt tgctgcccgg cgaaatgttc aatggcgtga tgcagcggcg caataccatg
    49441 taccacaatc ccgccgccga cgaggaacat cgccagcgtg ccgacaatcg ataacgcctt
    49501 catcaaccag ggcgcaatga tcaataaccc tttacctaat gcctgcatca gcgcgctgga
    49561 tttttccgcc agccaatacc ccaggtcatc aatcttaacg ataaccccta ccagaccgta
    49621 gacgcccacg gtcactacca gcgcgatgcc tgaaagcacc agcacctgat taagcaacgg
    49681 cgcttcggcc acaatcccca gcgtgatggc gacgatttcg gcagacaata taaaatcggt
    49741 acgaatcgcc ccttttattt tgtccttttc aaacttcagc ggatcctgcg ccgccagctt
    49801 ctccagacgc tgctggctct gcgccggatc ttctttatgt ttacgcgcct ccagcatatg
    49861 cagcactttc tctactcctt caaagcagag aaacgcgcca ccaatcatca acagaggcgt
    49921 aatcgcccac gggataaacg cactgatgat cagcgccagc ggcaccagaa tcactttatt
    49981 aatcagcgat cctttcgcca cgccccagac cacgggaagt tcccggttgg cccgcacgcc
    50041 tgaaacttgt tgcgcattga gcgataagtc atcccctaat acaccggcgg ttttcttcgc
    50101 cgccagtttg cccatcacgg agatatcgtc cagtagtgtg gcgatatcat cgagcaacgt
    50161 cagtaaacta ctcccggcca aaagcattcc ctctcatttt tattgttgaa gggtgtaagt
    50221 atgaagcaaa aacggcagct ctgatacttg cttcacaggt caacattttt ttaacaatta
    50281 agtgcaatta tatctctcgc cagcagaatg attttcacgt ttactatgaa ccaccttttt
    50341 atttccaccg tgagggatta tgcgtttccg ccagttgtta ccgctttttg gcgcgctgtt
    50401 tgcgttgtat atcatttggg gctcaaccta ttttgtcatt cggattggcg tggaaagctg
    50461 gcctccgtta atgatggcag gcgttcgatt cctggcagcc ggtattttat tgatggcatt
    50521 tttgctactg cgcggacaca agctcccccc gctacgtccg ctgctcaatg ccgcgctgat
    50581 tggcctgtta ttgctggctg tcggtaatgg catggtgacg gttgccgagc atcaaaatgt
    50641 tccttccggc atcgccgccg ttgtggttgc aaccgtgccc ctctttaccc tgtgcttcag
    50701 ccgcctgttt ggcattaaaa cgcgcaaact ggaatgggtg ggtatcgcca ttgggcttgc
    50761 cggaatcatc atgctcaata gcggtggaaa tttaagcggc aatccgtggg gcgcgattct
    50821 gattttaatc ggctcgatta gctgggcgtt tggctcggtt tatggctcgc gcattacctt
    50881 acctgtaggg atgatggcgg gtgctattga gatgctggcg gcaggcgtgg tgttaatgat
    50941 cgcgtcgatg attgcaggtg aaaaactgac ggcgctccct tccctttcag gcttccttgc
    51001 ggtcggctat ctggcgctgt ttggttcgat tatcgccatc aacgcttata tgtatttaat
    51061 ccgtaatgtc agtccggctc tcgccaccag ctacgcctac gttaacccgg tggtcgcggt
    51121 cttgctgggt acgggactgg gcggagagac gctgtcgaag attgaatggc tggcgctcgg
    51181 cgtaattgtc ttcgcggtgg tgctggtcac gttgggaaaa tatctctttc cggcaaaacc
    51241 cgtagttgcg ccagttattc aggacgcatc aagcgagtaa atgaatcccc tgcgtgtcga
    51301 tctgcgcgct ggcaccttcg ccgcagatcc actcttccag acgctcgcta agcgcttcat
    51361 ccgtcagctt ctcgcgccca cgtaacgcgc actcccagac aatcaatacg cgccagccga
    51421 gttcctgcaa gcgactgata tcgcggcgat cgcgctcaac atttttacct atcttctcca
    51481 gccagaactc ggttcgagtc gcaggcactt taaacagata gcagtgatga tgatgccaga
    51541 agcagccgtg ggtaaatatc acgcagcgat attcatcaac gacaaaatcc gggcgtccgg
    51601 gcagactggc gtcctgaacg cgaaacgcca ggccctgccc ggttaacaga ctggcgaggc
    51661 gcttctctat cgccgtatca cgcgtggcaa tcgcgcgcat atttttgctg cgagtggcct
    51721 tatcgtgaac gtcggccatg ttgtgcctct tgctgacgca acgccaccgc ctgtttgatt
    51781 tttggctcaa gcagttttgc caccgcggca aagaccggca cgaccaccga gttaccgaac
    51841 tggcgatagg cctgagtgtc cgaaaccgga atgcggaatt tcgcttctcc cggcgcttca
    51901 aaacccatta agcgcgcgca ttcacgaggc gttaaccgac gtggacgatg ttgctgattc
    51961 tgcggatcgt caaagtcttt ctcacctttg gccatatccc agccgcgatc gattaaaatt
    52021 tccgcgccat ctttgtaata acgcgcagac agcgtacgcg tgacgctttg cggattgttc
    52081 ggataaacca ttccataacc gaagccgtta ccgcgcgcct gatgtttttt cgcatatcga
    52141 tagaggtact tccacagcac cggcgtcagg atatatttcg cctcgaccat cgggtccagc
    52201 agctgcgcca gcgtcactcg ctgcgcaggg aaacattcgc tgatatcacg cagggtaaaa
    52261 tcggctttca gattcagatc gcgacgaaaa cccaccagca cgatgcgttc acggtgctgt
    52321 ggcagaaaat gtttgccgtc gatgattttc ggatcgtctg gcccgttatc ttctgcatca
    52381 gccacgtcat agcccagttc gtccagcgtc tgcatgatga tgcggaacgt tttaccctgg
    52441 tcatggcttt tcaggttttt gacgttttcg agcacaaaca tcgccggacg acgcgagtcg
    52501 ataatgcgca ccacatcaaa aaacagcgtg ccctgggtat cgcaggcaaa accgtgcgcc
    52561 cgcccgagcg agttcttttt cgatacgcca gccagcgaaa atggctgaca agggaaaccg
    52621 gccagtaaaa catcgtgttc aggaatgtgt tgacgaatat gttccgccgc cgcctcatca
    52681 ctcacgcctt ctttatggct gagggtgatg tcgcggatat cttcattaaa atgatgcgtc
    52741 gccgggtcgc aataatgatt ggctttataa gtgcgtaccg catgtttgtt ccattcgctg
    52801 gtaaacacgc actgtccgcc aatcgattca aaaccgcgac ggatgccgcc aattccggca
    52861 aatagatcga taaagcgaaa cgcataatgc ggatgatgtg ccggtggttt gggtaacaac
    52921 gtttgcagat gggcgaactc tttctcactt aaacggtgcc atgccgagtc attcgccagc
    52981 gcacgtttta aaattgccgc gctccagtga ttctcaccca caccattaag ctgcgccacc
    53041 agcgttttaa catcataaat ttgcagcagt ttctccagca ttgcctgtgc ggcattcccg
    53101 gtgctgtatg aatcggttac tgatatattt tcctgcatag atttaaccgg ccatctgaga
    53161 tggccgacag gttaacataa ttacagccat ttagggccac gcgcttatcc cgcgggtgaa
    53221 aacgcatcta tcaccttgtg atcgacacct tcattctccc ccgccagttc ggcactgagc
    53281 ttcgccataa actcgactaa aaaatgcgcg ttgtgctgcg ccagctgctt gcctcttgcg
    53341 gtttgcatgg tttgcggtag cttcagcaac ttagtctgga aatgatccag cgcgtagcgt
    53401 ttatcatcaa gcgggcgatg ctgtgcgaac ggatcttcac catcaaacag cgccacgccc
    53461 aatgcccctg aaacggcaaa cacgcgcgcc aggccaatcg cccccagggc ttccagccga
    53521 tccgcatcct ggacgatttt agcttccgtt gttaaggggg cgatttgcgc gctgaaactg
    53581 tgagcggcaa tggcatgaca aacggcctcg attttctccg ccggaaattg ctcgaactct
    53641 tcacggagca ggcgacgcgt ctcttctgcc gccaggattg aagaacgctg cctttgcgga
    53701 tgatttttcg ccaggctcac aatatcgtga aaataacagg cggttaaaat caccagcata
    53761 tcgacatcgt catctgccgc cagcttctgt gccgtagccc agacgcggcg aaaatgacac
    53821 acgtcatggg ccgcgccctg gtgctgatga tggtttttca accagttttc gaactgtgcc
    53881 tgccagtgtt gtaagtccat acgcgctccg ttgccaaaga gtcgccacct tagcagtttt
    53941 tattcatagc gtctgctacg tgcgggacga ggtcgggtgt accaggcaat gctgcctaac
    54001 aatgccccga ccagagccat aaataaaaat ccgaccagtg cccctaacca ctttcccgcg
    54061 gtagagccta aatcgctttc aaatcccgac accggggcat cggggatccg gctcatcacc
    54121 cagatgtaac gcgccattgc ccagacgaaa tagccacacc atgtatagaa agcccacaaa
    54181 gccagtttgc caccagggct gcgagagagt ctctcttcca tctttgtcga accgtattcc
    54241 attttgagat aacccggaaa attcagactt agcactatta tgtgataaaa gtcacatttt
    54301 tccacattgg atgagccagt caagactcac tcattttttg aacaaataga taatttttgc
    54361 gcaacggcag tgaatacagg aaaaatcgtt ttgagcgatt ttatttatct ttgagatcgg
    54421 ctttattaat tcatttaatc aatatattag cactgaatac aattatacct ttttattttt
    54481 ctgtgtcatg atgcctccgt tattagcctt ttatcgtctt gtttatattt tttgggccgg
    54541 catgatgccg gctttttttt atgccttcat taatgtgcgc gtgatcacac cagccgtttg
    54601 gcgcaacaat cattgatacc ccctatgctt ccgctcaact cataacatat tgatatacat
    54661 ttataatttt catgaatatt tatatt
//
LOCUS       DAZUDJ010000028        54570 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.028, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000028 DAZUDJ010000000
VERSION     DAZUDJ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 54570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54570
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.028"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(338..1738)
                     /gene="asnS"
                     /locus_tag="ACHY1N_002265"
     CDS             complement(338..1738)
                     /gene="asnS"
                     /locus_tag="ACHY1N_002265"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFS4044566.1"
                     /translation="MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGW
                     VEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQN
                     VRDVIPFPRTPRNANF"
     gene            complement(1907..3109)
                     /gene="pncB"
                     /locus_tag="ACHY1N_002266"
     CDS             complement(1907..3109)
                     /gene="pncB"
                     /locus_tag="ACHY1N_002266"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706850.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFS4044567.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGD
                     DLLGIYADAIREQIQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSN
                     DNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSAL
                     TAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQ
                     AHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASR
                     YQGLRHDSGDPVEWGEKAIVHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPHIKKAS"
     gene            3375..5987
                     /gene="pepN"
                     /locus_tag="ACHY1N_002267"
     CDS             3375..5987
                     /gene="pepN"
                     /locus_tag="ACHY1N_002267"
                     /EC_number="3.4.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HFS4044568.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVR
                     HGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEISPAA
                     NTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTV
                     KDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNS
                     VLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNE
                     MAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRN
                     ACLRFLAFGETHLADVLVSKQYHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWH
                     QDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFH
                     AEDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            complement(6194..6961)
                     /gene="ssuB"
                     /locus_tag="ACHY1N_002268"
     CDS             complement(6194..6961)
                     /gene="ssuB"
                     /locus_tag="ACHY1N_002268"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonates ABC transporter ATP-binding
                     protein"
                     /protein_id="HFS4044569.1"
                     /translation="MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVG
                     RSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVG
                     LGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPL
                     GALDALTRLEMQDLIVSLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVD
                     IPRPRRLGSVRLAELEAEVLQRVMRRGHSEQLIRRHG"
     gene            complement(6958..7749)
                     /gene="ssuC"
                     /locus_tag="ACHY1N_002269"
     CDS             complement(6958..7749)
                     /gene="ssuC"
                     /locus_tag="ACHY1N_002269"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415454.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter permease
                     SsuC"
                     /protein_id="HFS4044570.1"
                     /translation="MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEG
                     VVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQ
                     MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARS
                     YGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREF
                     LQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV"
     gene            complement(7760..8905)
                     /gene="ssuD"
                     /locus_tag="ACHY1N_002270"
     CDS             complement(7760..8905)
                     /gene="ssuD"
                     /locus_tag="ACHY1N_002270"
                     /EC_number="1.14.14.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008726 - alkanesulfonate monooxygenase
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FMNH2-dependent alkanesulfonate monooxygenase"
                     /protein_id="HFS4044571.1"
                     /translation="MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGY
                     TGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGR
                     ALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLLGETVNFNGKHIHVRGA
                     KLLFPPIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPELVKEKIEQVRAKAAAH
                     GRKIRFGIRLHVIVRETNDEAWQAAERLISHLDDETIAKAQAAFARTDSVGQQRMAAL
                     HNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPH
                     LEEAYRVGELLFPHLDVAIPEIPQPQPLNPQGEAVANDFIPRKVAQS"
     gene            complement(8902..9861)
                     /gene="ssuA"
                     /locus_tag="ACHY1N_002271"
     CDS             complement(8902..9861)
                     /gene="ssuA"
                     /locus_tag="ACHY1N_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein SsuA"
                     /protein_id="HFS4044572.1"
                     /translation="MRNIIKLALVGLLSVSTIAVAAESSPEALRIGYQKGSIGMVLAK
                     SHQLLEKRYPQSKISWVEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLVYVG
                     VEPPKPKAEVILVAENSPIKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQP
                     TYLTPADTRAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPY
                     AEKNGAFIQGVLATFSEADALTRSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKP
                     VNAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQL"
     gene            complement(9854..10429)
                     /gene="ssuE"
                     /locus_tag="ACHY1N_002272"
     CDS             complement(9854..10429)
                     /gene="ssuE"
                     /locus_tag="ACHY1N_002272"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_process: GO:0046306 - alkanesulfonate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFS4044573.1"
                     /translation="MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAP
                     EDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVV
                     LPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTR
                     LDTALETFWQALHRRDVQVPDLLSLRGNAHA"
     gene            10785..11327
                     /locus_tag="ACHY1N_002273"
     CDS             10785..11327
                     /locus_tag="ACHY1N_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415458.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4044574.1"
                     /translation="MKKSVLTAFITVVCATSSVMAADDNAITDGKVTFNGKVIAPACT
                     LVAATKDSVVTLPNVSATKLQTNGAVSGVKTDVPIALEGCDVTVTKNATFTFSGTADG
                     VQPTAFANQATTDAATNVALQMYLPDGSTSVTPGTETSNIQLADSAEQTVTFKVDYIA
                     TGKATSGNVNAVTNFHINYY"
     gene            11410..12111
                     /gene="elfD"
                     /locus_tag="ACHY1N_002274"
     CDS             11410..12111
                     /gene="elfD"
                     /locus_tag="ACHY1N_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0061077 - chaperone-mediated protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HFS4044575.1"
                     /translation="MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEG
                     EEQISLGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGA
                     PLAKDRETLFFTSVRAVPSTTKREEGNTLKIATQSVIKLFWRPKGLAYPLGEAPAKLR
                     CTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRT
                     INDYGAETPQLNCKS"
     gene            12136..14736
                     /gene="elfC"
                     /locus_tag="ACHY1N_002275"
     CDS             12136..14736
                     /gene="elfC"
                     /locus_tag="ACHY1N_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0015473 - fimbrial usher porin activity
                     [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HFS4044576.1"
                     /translation="MYRTHRQHSLLSSGGVPSFIGGLVVFVSAAFNAQAETWFDPAFF
                     KDDPSMVADLSRFEKGQKITPGVYRVDIVLNQTIVDTRNVNFVEITPEKGIAACLTTE
                     SLDAMGVNTDAFPAFKQLDKQACVPLAEIIPDASVTFNVNKLRLEISVPQIAIKSNAR
                     GYVPPERWDEGINALLLGYSFSGANSIHSSADSDSGDSYFLNLNSGVNLGPWRLRNNS
                     TWSRSSGQTAEWKNLSSYLQRAVIPLKGELTVGDDYTAGDFFDSVSFRGVQLASDDNM
                     LPDSLKGFAPVVRGIAKSNAQITIKQNGYTIYQTYVSPGAFEISDLYSTSSSGDLLVE
                     IKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAKYRTNSNEQQESKFAQATLQWGGP
                     WGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDVTQAKSTLADQSEHKGQSYRFLY
                     AKTLNQLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGYEFNDGDDEDTPMWSRYYNLFY
                     TKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLLQFGYNTQIKDLSLGVSWNY
                     SKSRGQPDADQVFALNFSLPLNLLLPRSNDSYTRKKNYAWMTSNTSIDNEGHITQNLG
                     LTETLLDDGNLSYSVQQGYNSEGKTANGSASMDYKGAFADARVGYNYSDNGSQQQLNY
                     ALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGLKTDWRGYTVVPYATSY
                     RENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGARVLMKTSKQGIPLRF
                     GAIATLDGIQTNSGIIDDDGSLYMSGLPAQGAITVRWGEAPDQICHISYQLTEQQINS
                     AITRMDAICR"
     gene            14727..15797
                     /gene="elfG"
                     /locus_tag="ACHY1N_002276"
     CDS             14727..15797
                     /gene="elfG"
                     /locus_tag="ACHY1N_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4044577.1"
                     /translation="MQIIFGEKCVLLLRLFFAAVLMLWCAQTAAYSGQCHTTQGNPYI
                     GVNFGVKTLEEEENTAGVVKDKFYQWNESNDYYVSCDCDKDNVRSGRWAFAADSPLVY
                     LGDNWYKINDYLAAKVLLQVKGSSPTAVPFENVGTGADTRWHICDPGGQRLGGQGASG
                     NSGSFSLKILQPFVGSVVIPPMALARLFECYNIPAGDSCTTTGTPVLVYYLSGTINSL
                     GSCSVNAGETIEVDLGDVFAANFRVVGHKPLGARTAELAIPVRCNTGNAGLVNVNLSL
                     TATTDPSYPQAIKTSRPGVGVVVTDSQNNIISPAGGTLPLSIPDDADSIARMNVYPVS
                     TTGVPPETGRFEATATVRINFD"
     gene            15809..16351
                     /gene="ycbU"
                     /locus_tag="ACHY1N_002277"
     CDS             15809..16351
                     /gene="ycbU"
                     /locus_tag="ACHY1N_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4044578.1"
                     /translation="MKKKTIFQCVILFFSILNIHVGMAGPEQVSMHIYGNVVDQGCDV
                     ATKSALQNIHIGDFNISDFQAANTVSTAADLNIDITGCAAGITGADVLFSGEADTLAP
                     TLLKLTDTGGSGGMATGIAVQILDAQSQQEIPLNQVQPLTPLKAGDNTLKYQLRYKST
                     KAGATGGNATAVLYFDLVYQ"
     gene            16359..16874
                     /gene="ycbV"
                     /locus_tag="ACHY1N_002278"
     CDS             16359..16874
                     /gene="ycbV"
                     /locus_tag="ACHY1N_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415463.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4044579.1"
                     /translation="MLKRIIWILFLLGLTGGCELFAHDGTVNISGSFRRNTCVLAQDS
                     KQINVQLGDVSLTRFFHGNYGPEKSFIINLQDCGTDVSTVDVTFSGTPDGVQSEMLSI
                     ESGTDAASGLAIAILDDAKILIPLNQASKDYSLHSGKVPLTFYAQLRPVNSDVQSGKV
                     NASATFVLHYD"
     gene            16840..17577
                     /gene="ycbF"
                     /locus_tag="ACHY1N_002279"
     CDS             16840..17577
                     /gene="ycbF"
                     /locus_tag="ACHY1N_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HFS4044580.1"
                     /translation="MPARHLYFIMTNTWNRLALLIFAVLSLLVAGELRAGVVVGGTRF
                     IFPADRESISILLTNTSQESWLINSKINRPTRWAGGEASTVPAPLLAAPPLILLKPGT
                     TGTLRLLRTESDILPVDRETLFELSIASVPSGKVENQSVKVAMRSVFKLFWRPEGLPG
                     DPLEAYQQLRWTRNSQGVQLTNPTPYYINLIQLSVNGKALSNAGVVPPKSQRQTSWCQ
                     AIAPCHVAWRAINDYGGLSAKKEQNLP"
     gene            17688..18698
                     /gene="pyrD"
                     /locus_tag="ACHY1N_002280"
     CDS             17688..18698
                     /gene="pyrD"
                     /locus_tag="ACHY1N_002280"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006222 - UMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HFS4044581.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPA
                     KPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICME
                     KIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKI
                     APDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKST
                     EIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVT
                     HI"
     gene            18872..19414
                     /gene="zapC"
                     /locus_tag="ACHY1N_002281"
     CDS             18872..19414
                     /gene="zapC"
                     /locus_tag="ACHY1N_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415466.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HFS4044582.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAF
                     SPAGFCVDDAALYFSFEEKCRDFNLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHG
                     EMWVPMPGDAACVWLSDTHEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKI
                     MNDRLKPQVNVDSFSLEQAV"
     gene            complement(19411..20520)
                     /gene="ycbX"
                     /locus_tag="ACHY1N_002282"
     CDS             complement(19411..20520)
                     /gene="ycbX"
                     /locus_tag="ACHY1N_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein YcbX"
                     /protein_id="HFS4044583.1"
                     /translation="MVTLTRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGT
                     FITARQFPQMVRFTPSPVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIA
                     PDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQ
                     RCPASVKMEQFRPNLVVSGASAWEEDSWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQ
                     KHPAGEPLKTLQSFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAA
                     ADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQ
                     LLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLAR"
     gene            20764..22872
                     /gene="rlmKL"
                     /locus_tag="ACHY1N_002283"
     CDS             20764..22872
                     /gene="rlmKL"
                     /locus_tag="ACHY1N_002283"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008990 - rRNA
                     (guanine-N2-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HFS4044584.1"
                     /translation="MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLV
                     YQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLH
                     LRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGL
                     HRGRWGFSGWVQHDEDIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNAR
                     LAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYGERLDSEPALIALHSLLGRIMK
                     NQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVA
                     EDYANRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTI
                     DAHKARQRLFDIIAATISVLGIAPNKLVLKTRERQKGKNQYQKLGEKGEFLEVTEYNA
                     HLLVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGGARSTTT
                     VDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKR
                     MEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKT
                     LSQDFARNRQIHNCWLITAA"
     gene            22883..24790
                     /gene="uup"
                     /locus_tag="ACHY1N_002284"
     CDS             22883..24790
                     /gene="uup"
                     /locus_tag="ACHY1N_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4044585.1"
                     /translation="MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYH
                     DISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERGERREVMGTAKMQVEEASRSGKIVFEMEDVCYQVDGKQL
                     VKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPDKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDSYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYVGGYHDARGQQEQSVALKQPAVKKTEEAAAAKAETVKRSSSKLSYKL
                     QRELEQLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFER
                     WEYLEALKNGG"
     gene            24920..26173
                     /gene="pqiA"
                     /locus_tag="ACHY1N_002285"
     CDS             24920..26173
                     /gene="pqiA"
                     /locus_tag="ACHY1N_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HFS4044586.1"
                     /translation="MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTF
                     FLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
                     KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIR
                     QGLRSCSCCTAILPADEPVCPRCSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIM
                     VADLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDRQPESEHEES"
     gene            26178..27818
                     /gene="pqiB"
                     /locus_tag="ACHY1N_002286"
     CDS             26178..27818
                     /gene="pqiB"
                     /locus_tag="ACHY1N_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HFS4044587.1"
                     /translation="MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPE
                     VTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDT
                     VFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRV
                     ILDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTNNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYR
                     IPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNT
                     PAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRT
                     MKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            27815..28378
                     /gene="pqiC"
                     /locus_tag="ACHY1N_002287"
     CDS             27815..28378
                     /gene="pqiC"
                     /locus_tag="ACHY1N_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HFS4044588.1"
                     /translation="MKKWLVTIAALWLAGCSSGEINKNYYQLPVVQSGTQSTASQGNR
                     LLWVEQITVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGW
                     VVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDG
                     YDEMVKVLAGVWSQEAASIAQEIKRLP"
     gene            28634..28801
                     /gene="rmf"
                     /locus_tag="ACHY1N_002288"
     CDS             28634..28801
                     /gene="rmf"
                     /locus_tag="ACHY1N_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0141014 - ribosome hibernation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HFS4044589.1"
                     /translation="MKRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSQWLGGW
                     REAMADRVVMA"
     gene            complement(28871..29389)
                     /gene="fabA"
                     /locus_tag="ACHY1N_002289"
     CDS             complement(28871..29389)
                     /gene="fabA"
                     /locus_tag="ACHY1N_002289"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008693 -
                     (3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HFS4044590.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASD
                     LKVGLFQDTSAF"
     gene            complement(29458..31218)
                     /gene="ycbZ"
                     /locus_tag="ACHY1N_002290"
     CDS             complement(29458..31218)
                     /gene="ycbZ"
                     /locus_tag="ACHY1N_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4044591.1"
                     /translation="MTITKLAWRDLVPDTDSYQEIFAQPHLIDENDPLFSDTQPRLQF
                     ALEQLLHTRASSSFMLAKAPEESEYLNLIANAARTLQSDAGQLVGGHYEVSGHSIRLR
                     HAVSADDNFATLTQVVAADWVEAEQLFGCLRQFNGDITLQPGLVHQANGGILIISLRT
                     LLAQPLLWMRLKNIVNRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELSEQAIYSEFEDTLQIVDAESVTQWCRWVTFTARHNHLPAPGADAWPVLIREAA
                     RYTGEQETLPLSPQWILRQCKEVASLCDGDTFSGEQLNLMLQQREWREGFLAERMQDE
                     ILQEQILIETEGERIGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFTDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LADVPVNQSIAITGSVDQFGRAQPVGGLNEKIEGFFAICQQRELTGKQGVIIPTANVR
                     HLSLHSELVKAVEEGKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQASQ
                     QEGRHRFPWPLRWLNWFIPN"
     gene            31404..31856
                     /gene="matP"
                     /locus_tag="ACHY1N_002291"
     CDS             31404..31856
                     /gene="matP"
                     /locus_tag="ACHY1N_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HFS4044592.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVL
                     LSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE"
     gene            complement(31932..32972)
                     /gene="ompA"
                     /locus_tag="ACHY1N_002292"
     CDS             complement(31932..32972)
                     /gene="ompA"
                     /locus_tag="ACHY1N_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HFS4044593.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGF
                     INNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTA
                     KLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRL
                     EYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLK
                     SDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSER
                     RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV
                     KGIKDVVTQPQA"
     gene            complement(33329..33838)
                     /gene="sulA"
                     /locus_tag="ACHY1N_002293"
     CDS             complement(33329..33838)
                     /gene="sulA"
                     /locus_tag="ACHY1N_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0051782 - negative regulation of cell
                     division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SOS-induced cell division inhibitor SulA"
                     /protein_id="HFS4044594.1"
                     /translation="MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPM
                     MTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVES
                     MVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
                     LKIHSNLYH"
     gene            34057..34686
                     /gene="sxy"
                     /locus_tag="ACHY1N_002294"
     CDS             34057..34686
                     /gene="sxy"
                     /locus_tag="ACHY1N_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRP-S regulon transcriptional coactivator Sxy"
                     /protein_id="HFS4044595.1"
                     /translation="MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVS
                     DGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYS
                     LDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
                     SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE"
     gene            complement(34649..36811)
                     /gene="yccS"
                     /locus_tag="ACHY1N_002295"
     CDS             complement(34649..36811)
                     /gene="yccS"
                     /locus_tag="ACHY1N_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309071.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YccS family putative transporter"
                     /protein_id="HFS4044596.1"
                     /translation="MAFMLSPLLKRYTWNSAWLYYARIFIALCGTTAFPWWLGDVKLT
                     IPLTLGMVAAALTDLDDRLAGRLRNLIITLFCFFIASASVELLFPWPWLFAIGLTLST
                     SGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIG
                     HLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDESQAPLYDLALANGQLMATLN
                     QTKLSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFR
                     FQRLMSMQGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALERMRDNGAPADLLKTL
                     GFLLNNLRAIDAQLATIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTPESA
                     LFRHAVRMSLVLCFGYAIIQITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLV
                     GIAIGIPVLWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEG
                     FEVALPRVIDTLIGCAIAWAAVSYIWPDWQFRNLPRMLERATEANCRYLDAILEQYHQ
                     GRDNRLAYRIARRDAHNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYIS
                     ALGAHREQLTNPEILAFLDDAVCYVDDALHHQPADEERVNEALASLKQRMQQLEPRAD
                     SKEPLVVQQVGLLIALLPEIGRLQRQITQVPQETPVSA"
     gene            complement(36821..37267)
                     /gene="yccF"
                     /locus_tag="ACHY1N_002296"
     CDS             complement(36821..37267)
                     /gene="yccF"
                     /locus_tag="ACHY1N_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFS4044597.1"
                     /translation="MRTVLNILNFVLGGFATTLGWLLATLVSIMLIFTLPLTRSCWEI
                     TKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNIFWLIFFGWWLCLMHIATGIAQC
                     ISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE"
     gene            37390..39444
                     /gene="helD"
                     /locus_tag="ACHY1N_002297"
     CDS             37390..39444
                     /gene="helD"
                     /locus_tag="ACHY1N_002297"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HFS4044598.1"
                     /translation="MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLL
                     AIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRFYHHLDAHWQRWSGEMSEIASGV
                     LRQQLDLIATRTGENKWLTREQTSGVQQQIRQAMSALPLPVNRLEEFDNCREAWRKCQ
                     AWLKDIESARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGA
                     GSGKTSVLVARAGWLLARGEASPEQILLLAFGRKAAEEMDERIRERLHTEDITARTFH
                     ALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQ
                     WSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLM
                     APLLKAWKGALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALL
                     AALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGDRCDLDTTYRFNSRI
                     GEVANRFIQQNPGQLKKPLNSLTNGDEKAVTLLDESQLDALLDKLSGYAKPEERILIL
                     ARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVIIVGLQEGSDGFPAAARES
                     IMEEALLPPVEDFPDAEERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVAR
                     KP"
     gene            complement(39476..39934)
                     /gene="mgsA"
                     /locus_tag="ACHY1N_002298"
     CDS             complement(39476..39934)
                     /gene="mgsA"
                     /locus_tag="ACHY1N_002298"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415483.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFS4044599.1"
                     /translation="MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYA
                     TGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK"
     gene            complement(40030..40692)
                     /gene="yccT"
                     /locus_tag="ACHY1N_002299"
     CDS             complement(40030..40692)
                     /gene="yccT"
                     /locus_tag="ACHY1N_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HFS4044600.1"
                     /translation="MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLL
                     RGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLE
                     NEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASL
                     PQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQP
                     SS"
     gene            40865..41278
                     /gene="yccU"
                     /locus_tag="ACHY1N_002300"
     CDS             40865..41278
                     /gene="yccU"
                     /locus_tag="ACHY1N_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFS4044601.1"
                     /translation="MKETDIAGILTSTHTIALVGASDKPDRPSYRVMKYLLDQGYHVI
                     PVSPKVAGKTLLGQQGYGTLADVPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWMQL
                     GVINEQAAVLARDAGLNVVMDRCPAIEIPRLGLAK"
     gene            complement(41323..41640)
                     /gene="hspQ"
                     /locus_tag="ACHY1N_002301"
     CDS             complement(41323..41640)
                     /gene="hspQ"
                     /locus_tag="ACHY1N_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HFS4044602.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVND
                     ELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPR
                     LRN"
     gene            complement(41698..42888)
                     /gene="rlmI"
                     /locus_tag="ACHY1N_002302"
     CDS             complement(41698..42888)
                     /gene="rlmI"
                     /locus_tag="ACHY1N_002302"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415487.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HFS4044603.1"
                     /translation="MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVD
                     HQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFSRRLQQAQKWRDWLAQKDGLDSY
                     RLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECAIYDRSDVA
                     VRKKEGMELTQGPVTGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRY
                     VENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFV
                     RDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEDGI
                     LLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFA
                     CRVM"
     gene            42983..43261
                     /gene="yccX"
                     /locus_tag="ACHY1N_002303"
     CDS             42983..43261
                     /gene="yccX"
                     /locus_tag="ACHY1N_002303"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003998 - acylphosphatase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFS4044604.1"
                     /translation="MSKVCIIAWVYGRVQGVGFRYTTQYEAKRLGLTGYAKNLDDGSV
                     EVVACGEEGQVEKLVQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR"
     gene            complement(43258..43587)
                     /gene="tusE"
                     /locus_tag="ACHY1N_002304"
     CDS             complement(43258..43587)
                     /gene="tusE"
                     /locus_tag="ACHY1N_002304"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HFS4044605.1"
                     /translation="MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAKNEGISLSPEHW
                     EVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(43678..44337)
                     /gene="yccA"
                     /locus_tag="ACHY1N_002305"
     CDS             complement(43678..44337)
                     /gene="yccA"
                     /locus_tag="ACHY1N_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HFS4044606.1"
                     /translation="MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGM
                     GDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            complement(44745..45764)
                     /locus_tag="ACHY1N_002306"
     CDS             complement(44745..45764)
                     /locus_tag="ACHY1N_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4044607.1"
                     /translation="MGRPRKNKKDNVLPPRVRSNGYSYVWKPEGSTRSIGLGRVRKTS
                     VAKVWQNYELEKAKLHNIMTVAKLWHMFMDSPAFTELAPRTQKDYRQHQKALLMVFGK
                     VLADNVKTEQVRIFMDKRGLESKTQANHELASLSRVYGWGYERGYVKNNPCKGVRKFS
                     LKARTVYITDEQYAAIYAEAIPQLRIAMEISYLCAARLGDVLELKWQDIMDKGIYIEQ
                     NKTGTKQIKEWSPRLRTAIQLARNVSSCTCEYVINTTKGGKVIAKTLNNWWNQAKRAA
                     EQKVGVPFGCNFHDIKAKGISDYEGSSRDKQIFSGHKTENQVLIYDRKTKITPTLDLP
                     LVVSK"
     gene            complement(45742..45984)
                     /locus_tag="ACHY1N_002307"
     CDS             complement(45742..45984)
                     /locus_tag="ACHY1N_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_303789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4224 domain-containing protein"
                     /protein_id="HFS4044608.1"
                     /translation="MYELTLSPAEIKEITKYERYTKQQHQLRLHGIPFVIGPKNEPIV
                     LRRDIPHGLTTMPKTSELVSAEPDFEALNNGKTKKK"
     gene            complement(46052..48523)
                     /locus_tag="ACHY1N_002308"
     CDS             complement(46052..48523)
                     /locus_tag="ACHY1N_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HFS4044609.1"
                     /translation="MSKIFICAAIPDEQAIKEDSAVAVATAIEAGDERRARAKFHWQF
                     LEQFPAAQDCAYKFIVCEDKPGIPRPALDSWDTEYMQENRWDEESASFVPVEPESDPM
                     NVNFDKLSPEVQNAVLVKFDTCENITVDMVISAQELLQEDMATFGGHIVEALMKMPEV
                     NAMYPELKLHAIGWVKHKCEPGAKWPEIQAEMRIWKKRREGERKETGKYTSVVDLTRA
                     RVNQQNTENAAEKTGAVTVAIRREYKQTWKTLDNELACALWPGDVDAGNIDGTIHRWA
                     TNEVIDKDREDWKRISASMRKQPEALGYDRQTIFGLVRERPIDIHKDPVALNKYISEY
                     LTTKGVFEHEETDQSSTDALQPSAAQTAPVETAESDTQKNEILVEAEPSVEREGPFYF
                     VFTDKGGEKYGRANKLSGLDKALAAGGTEISKEEYFARKNGTYTGLPQNVDTAEDSEQ
                     SEPVKVTADEVNKIMQAANISQPDADKLLAASRGEFVEGISDPNDPKWVKGIQSRDAE
                     DQNQPNVKQNEPEAEQNSPDTQQNGPEEQQPEPAVQQELEKVCTACGQTGGGNCPDCG
                     AVMGNATYLETFDEENQAEAQKNDPEEMEGTEHLHKENTGSDQYHASDNKTGETANPL
                     IKVNGHHEISSTSRLWHHLMIDLETMGKNPDAPIISIGAIFFDPQTGEMGPEFSKTID
                     LETAGGVIDRDTIKWWLKQSREAQSAILTDEIPLDDALLQLREFIDENSGEFFVQVWG
                     NGATFDNVILRRSYERQGIPCPWRYTNDRDVRTMVALGLVMDFDARTTIPFEGERHNA
                     LNDARYQAKYVSAIWQKLLPSQADF"
     gene            complement(48617..48808)
                     /locus_tag="ACHY1N_002309"
     CDS             complement(48617..48808)
                     /locus_tag="ACHY1N_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1482 family protein"
                     /protein_id="HFS4044610.1"
                     /translation="MNTTFALVLTVYLVSGESLELVTGLYGSMKECMAAAAEQKIPGN
                     CYPVDKTTHTNNNEIPAGL"
     gene            complement(48805..48993)
                     /gene="dicB"
                     /locus_tag="ACHY1N_002310"
     CDS             complement(48805..48993)
                     /gene="dicB"
                     /locus_tag="ACHY1N_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibition protein DicB"
                     /protein_id="HFS4044611.1"
                     /translation="MEKLSCNASTSELRFEIGVITGDKTFIEDAIKQRKLEQDLLNEV
                     CIPSMLARLDLLQKGYKQ"
     gene            49567..49752
                     /locus_tag="ACHY1N_002311"
     CDS             49567..49752
                     /locus_tag="ACHY1N_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044612.1"
                     /translation="MPNKPCPACNALSGFLEKGGYYIFNCPEHVEFHISKLDSIITKP
                     NQYQSDLLNKELNAARD"
     gene            complement(49939..50328)
                     /locus_tag="ACHY1N_002312"
     CDS             complement(49939..50328)
                     /locus_tag="ACHY1N_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044613.1"
                     /translation="MEFKDLLKEIQEIAEHALHQRLNEVELESATKKYIDNMARNVRD
                     AFTGLYSVSVTNNQNTEETAKRIASVMGFHVEEKYSKKEFWKTTKKLQSENCHLLRQS
                     LLSMRKVIQMTQDYRNCSHYLKNSELS"
     gene            complement(50340..50468)
                     /gene="ydfB"
                     /locus_tag="ACHY1N_002313"
     CDS             complement(50340..50468)
                     /gene="ydfB"
                     /locus_tag="ACHY1N_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdfB"
                     /protein_id="HFS4044614.1"
                     /translation="MDFDTIMEKAYEEYFEGLAEGEEALSFSEFKQALSSSAKSND"
     gene            complement(50470..50625)
                     /locus_tag="ACHY1N_002314"
     CDS             complement(50470..50625)
                     /locus_tag="ACHY1N_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HFS4044615.1"
                     /translation="MDTIDLGNNESLVYGVFPNQDGTFTAMTYTKSKTFKTENGARRW
                     LERNSGE"
     gene            complement(50902..51189)
                     /locus_tag="ACHY1N_002315"
     CDS             complement(50902..51189)
                     /locus_tag="ACHY1N_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFS4044616.1"
                     /translation="MLPILWLPSARDDLRQIITYIAKENPPAARRLKIRIETSVLPLS
                     EHPYLYPPSERVSGLREIVTHPNYIILYRVAASSIEIVSVTHSRRQFPFSI"
     gene            complement(51189..51380)
                     /locus_tag="ACHY1N_002316"
     CDS             complement(51189..51380)
                     /locus_tag="ACHY1N_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFS4044617.1"
                     /translation="MGTALSPIVSEFETTEQENSYNEWLRTKVTSSLADTRPAIPHDE
                     VMAEMENLIAQIAVTNKSE"
     gene            complement(51408..51809)
                     /locus_tag="ACHY1N_002317"
     CDS             complement(51408..51809)
                     /locus_tag="ACHY1N_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309096.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4044618.1"
                     /translation="MMSALEVSMYRISKLLQETGWSQAELARRIGVTQQTVQQWVSGK
                     ATPKASSLDKLVEVSGHPLHWFLLPPEECEQIFTPDTMKIGPRQRELLQAFSAFPEED
                     QEKMLQEIKDKKKSMEETIARWLAAQKSRRA"
     gene            51918..52190
                     /locus_tag="ACHY1N_002318"
     CDS             51918..52190
                     /locus_tag="ACHY1N_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4044619.1"
                     /translation="MLDSTREKIRQKYTQAEIGRYMGVAQQTVWQWFSFGVPPKQVIP
                     LCQLMKWEVTPHEIRPDIYPNPTDGLPVGCKVNTSNAPELIHENQA"
     gene            52174..52599
                     /locus_tag="ACHY1N_002319"
     CDS             52174..52599
                     /locus_tag="ACHY1N_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin YdaT family protein"
                     /protein_id="HFS4044620.1"
                     /translation="MKIKHEHIRMAMNAWAHPDGEKVPAAKITKAYFELGMTFPELYD
                     DSHPEAMARNTQKIFRWVEKDTPDAVKKIQALLPAIEKAMPPPLVARMRSHSSAYFRE
                     LVETKERLVKDIDDFVASAIVLFDQMNRGGPAGNTLAVH"
     gene            complement(52806..53261)
                     /locus_tag="ACHY1N_002320"
     CDS             complement(52806..53261)
                     /locus_tag="ACHY1N_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044621.1"
                     /translation="MYFLKSLYQAHVLNVAATNRWCNSPEMLPDYRAWLRAETYLRLD
                     ILISELQKETASIHNLQGIDAVRILVSRHSALSIIEVRHLSFSELIFLLQPALESANI
                     PPEVIQYPPHVDEQLQDVPYNQRAGLTPCSEAEWDHSLLKKYQDLYNPQ"
     gene            53340..54455
                     /locus_tag="ACHY1N_002321"
     CDS             53340..54455
                     /locus_tag="ACHY1N_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFS4044622.1"
                     /translation="MRDYAKVSPRFWLGETGRELRKAGAEAQVVAFYLMTSPHANMLG
                     LYYLPVLYLAHETGLGLEGASKGLKRAVEAGFCSYDHDAEMVWVHEMAAWQVGETLKP
                     GDNRCAGVRNEYASLPENAFLSVFYDRYKTDFHLDVRRNNSRNSVRGFEGAFKGLRSQ
                     EQEQEQEKEQEQDKNTMVHGKKNTTNQAGDVQTVNPGQPAGTTPEADSAYALKADSGA
                     VQQVMTAGSEQSHQLQQPEADSAIQREADRVVPESTGQSVGRVDYPDVFEQVWREYPL
                     RAGANPKKSAFSAWKARLREGVPPETMLDGVRRYARYLAATGKAGTEFVQRATTFFGP
                     DRNFENPWLLPVSGTNNQRCVNHISEPDTEIPPGFRG"
     gene            54462..>54570
                     /locus_tag="ACHY1N_002322"
     CDS             54462..>54570
                     /locus_tag="ACHY1N_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HFS4044623.1"
                     /translation="MKNIAAAGVLERIRRLAPQASVPPYRTVEEWREWQL"
BASE COUNT        13848 a        13165 c        13980 g        13577 t
ORIGIN      
        1 acagcaattt ttatctattt atatgattta cttatattta aattaactaa acggaaattt
       61 tgtttctgat ggaaacttta tcgacctggc acaaaatcct ctttcagaca tccagaatgc
      121 caaaaaatag tatgaaaatt gtgctatcag ctaagaaaaa actaatccgc aataagaatg
      181 cgggttattt tttgtgcgta aatgttgcaa tgtaatattc cgtaacagga tgatcgttat
      241 ggcggggttg caaatagatt gcttgactta acaaacagat aacttgacag aaaggataaa
      301 aaagagccag caggcgctgg ctctttgagg aagaaaatca gaagttggcg ttgcgcggag
      361 tacgtgggaa cggaatcaca tcacgcacgt tttgcacgcc agttacgtaa gcaatcaggc
      421 gttcaaaacc aagaccgaaa cctgaatgcg gaacagtacc gtagcgacgc agatcgcgat
      481 accaccagta atcttcttta ttcaggccca tttccagcat acgctcgtcc agaacgtcca
      541 gacgttcttc acgctgggag ccaccaatga tctcaccgat gcccggagcc agaacgtcca
      601 tagccgcaac ggttttaccg tcttcgttga ggcgcatata gaacgcttta atatctttcg
      661 gatagttttt aaccactacc ggtgctttaa agtgttcttc cgccagataa cgctcatgct
      721 cagaagagag atcgacgccc cagtaaaccg ggttttcaaa cttcctgccg cagttttcga
      781 gaatggtcac tgcgtcggtg taatccacct gcgcgaaatc ggcctcaatg aagcgttcca
      841 gacgtgaaac ggcatcttta tctacgcgtt cagcgaagaa tttcatgtcg tctgcgcgtt
      901 cttcgagaac cgctttgaag acatatttca gcatggcttc agccagaccc gcgatatcgt
      961 tcaggttagc aaacgccact tccggctcca gcatccagaa ttccgccagg tgacggctgg
     1021 tgttggagtt ttcagcacgg aaagtcgggc cgaaggtata aattttggat aatgcgcaag
     1081 cgtaggtttc gccgttcaac tggccagata cggtcaggaa agactcttta ccaaagaagt
     1141 ctttgtcgaa atccactttg ccctgatcgt tacgcggcag gttttccaga tccagcgtag
     1201 aaacgcggaa catttcgcct gcaccttcgg tatcagatgc ggtaatcagt ggcgttgaaa
     1261 cccagaagaa tccctgctcg ttaaagaagc gatgcagtgc ctgcgccagc gtatggcgaa
     1321 cgcgcgcgac ggcaccaatc aggtttgtgc gcggacgcag gtgagcgact tcacgcagat
     1381 actcaatgct gtggcgtttt gccgccatcg ggtaagtgtc tggatcttca acccaaccag
     1441 caacttcaac tttgctggcc tgaatttcaa attgttgccc ctggcccggc gacgccacga
     1501 ctttacccgt cacaatgacc gagcagccgg tggtcagacg caggacgtct tcattgtaat
     1561 tgggcagaga attattgatg acagcctgta caggatcaaa gcaggaaccg tcataaacgg
     1621 cgaggaagga gatgccagct tttgaatctc ggcgggtacg tacccatccg cgtacggtga
     1681 cttcgctgtc aacggctacg cggccctgga gtacgtcggc tacaggcaca acgctcataa
     1741 tattctctct gttaatagtc ggaaaaaata aacacttgtc cacccgtaaa tggggggata
     1801 cctatgttac ctggcatctg caatcagaca agcagaattc gcaaatgcag cgaaagattt
     1861 cggaattaaa ggtaaaaaaa gggagccgat tagctccctg atgatattaa ctggcttttt
     1921 taatatgcgg aaggtcgaac gctttgcgca gcgcccgaac aaacgcttta tcgtggcaga
     1981 tagttttgcc agggctgtca gaaagtttcg ccaccggttt accgttacac tcaaccaact
     2041 taatcacaat attcaggggt tttacctggg ggatatcgca ggtcaggcga gtcccaatac
     2101 caaaacttaa ttgcacgcgg gaagagaagt ggcggtatag ctcaaccgct ttgcgtaaat
     2161 ccagattgtc agagaaaacc agcgttttac tctgtggatc aattcccagc ttttcataat
     2221 gtacaatggc tttttcaccc cattcaaccg ggtcgccaga gtcatgacgc aggccctgat
     2281 agcgactggc gaactcgaca ccgaaatcac gcaggaaagc atccatagtg atgcagtcgg
     2341 ttaatgcaat gccaagttgg tcgggatatt cttccagcca ggcagcaagt gcagctcgct
     2401 ggctgttggc tagatccggg ctgatttgct gatgtgcctg gaaccattcg tgtgcctgtg
     2461 ttcccatcgg cgtgagggaa agccgacgcg ccagatcgta gttgctggtg cccacgaacc
     2521 aggattcctg ttgcagacgc ttaacgatgg tttcttgtac ttcgcgagaa aaacggcgac
     2581 gggtgccaaa atccataaga tggaagcgcg acatatcaag gccggcggtt aacgccgaga
     2641 agtcgactaa tttgctttcc agcgtgtcga gggcttgcgc aacgtcggcc tgcggtgagc
     2701 gatagcgatg taccatttca ctgataaccg ccagcaaagg aacttcccag aggatgactt
     2761 cacgccacgg gccgcttaaa cgaatatcca gcttgccatt atcgttggat acggtgactt
     2821 gttccgggtt aaagcggaac tcgcgtaacc agttaagata gtcggcctta aagaaaggca
     2881 gagcagagag ccactgatat tcatcatcct gcaggcgcag gtgctgcatc gcctgaatct
     2941 gttcacgaat agcatcggca taaataccca gcagatcgtc acctcggcaa cgaaactccg
     3001 ccgcgacatg cacatcgtaa tagtgatgaa acacggcttg ctgcatatgc aacttataag
     3061 catctgtatc cagcaacgag tgcagaacag gagaagcgaa ttgtgtcata ggtgcgcagt
     3121 agcgtcctcg tacaggagcg tttagtacaa taaacatctt caggaactgc tggagtatac
     3181 cttgtttcgc aatttattga accccgatca caccatatgc cacctttctg gtcgatggca
     3241 ttacgcggtg tatgttataa aaatgtagca ataaaggcgt ttgtacctga aaagatgaag
     3301 attctgcata gcgcgattta cgcaacagga atagactgaa caccagactc tataaaagat
     3361 gctaaaggtt atttatgact caacagccac aagccaaata ccgtcacgat tatcgtgcgc
     3421 cggattacca gattactgat attgacttga cctttgacct cgacgcgcaa aagacggtcg
     3481 ttaccgcggt cagccaggct gtccgtcatg gtgcatcaga tgctccgctt cgtctcaacg
     3541 gcgaagacct caaactggtt tctgttcata ttaatgatga gccgtggacc gcctggaaag
     3601 aagaagaggg cgcactggtc atcagtaatt tgccggagcg ttttacgctt aagatcatta
     3661 atgaaataag cccggcggcg aatacggcgc tggaagggct ttatcagtca ggcgatgcgc
     3721 tttgcaccca gtgtgaagcc gaaggtttcc gccatattac gtattatctc gaccgcccgg
     3781 acgtgctggc gcgttttacc accaaaatta ttgccgataa aatcaaatat cccttcctgc
     3841 tttccaatgg taaccgcgtt gcgcaaggcg aactggaaaa cggacgccat tgggtacagt
     3901 ggcaggaccc gttcccgaaa ccgtgctacc tgtttgcgct ggtggcaggc gactttgatg
     3961 tactgcgcga tacctttacc acgcgttctg gtcgcgaagt agcactggag ctgtacgtcg
     4021 atcgcggcaa ccttgatcgc gcgccgtggg cgatgacctc gctgaaaaac tccatgaaat
     4081 gggatgaaga acgctttggc ctggagtatg acctcgacat ctatatgatc gtcgcggtgg
     4141 atttcttcaa tatgggcgca atggagaata agggtctgaa tatctttaac tccaaatatg
     4201 tgttggcccg caccgacacc gccaccgaca aagattatct cgatattgaa cgcgttatcg
     4261 gccatgaata tttccataac tggaccggta accgagtgac ctgccgcgac tggttccagc
     4321 tcagcctgaa agaaggttta accgtcttcc gcgatcagga attcagctct gaccttggtt
     4381 cccgcgcggt aaaccgtatc aataatgtgc gcaccatgcg cggattgcag tttgcggaag
     4441 acgccagccc gatggcgcac ccgatccgcc cggatatggt cattgagatg aacaacttct
     4501 acaccctgac cgtttacgag aagggcgcgg aagtgattcg catgatccac accctgctgg
     4561 gcgaagaaaa cttccagaaa gggatgcaac tatatttcga gcgccatgat ggcagcgcgg
     4621 caacctgcga cgactttgtg caggcgatgg aagatgcgtc gaatgtcgat ctctcccatt
     4681 tccgccgttg gtacagccag tccggcacgc cgattgtgac cgtcaaagac gactacaatc
     4741 cggaaaccga gcagtacacc ctgaccatca gccagcgcac gccagccacg ccggatcagg
     4801 cagaaaaaca gccgctgcat attccatttg ccatcgaatt gtatgacaac gaaggcaaag
     4861 tgatcccgtt gcagaaaggc ggtcatccgg tgaattccgt gctgaacgtc acccaggcgg
     4921 aacagacctt tgtttttgat aatgtctact tccagccggt gcctgcgctg ctgtgcgaat
     4981 tctctgcgcc agtgaaactg gaatataagt ggagcgatca gcaactgacc ttcctgatgc
     5041 gtcatgcgcg taatgatttc tcccgttggg atgcggcgca aagtttgctg gcaacctaca
     5101 tcaagctgaa cgtcgcccgt catcagcaag ggcagccgct gtctctgccg gtacatgtgg
     5161 ctgacgcttt ccgcgcggtg ctgctcgatg agaagattga tccggcgctg gcggcagaaa
     5221 tcctgacgct gccttctgtc aatgaaatgg ctgaactgtt cgatatcatc gacccgattg
     5281 ctattgccga agtacgcgaa gcactcactc gtactctggc gactgaactg gcggatgagc
     5341 tgctggctat ttacaacgcg aattaccaga gcgagtaccg tgttgagcat gaagatattg
     5401 caaaacgcac tctgcgtaat gcctgcctgc gcttccttgc ttttggtgaa acgcatctgg
     5461 ctgacgtgct ggtgagcaag caataccatg aagcaaacaa tatgaccgat gcgctggcag
     5521 cgctttctgc ggcggttgct gcacagctgc cttgccgtga cgcgctgatg caggagtacg
     5581 acgataagtg gcatcaggac ggtctggtga tggataaatg gtttatcctg caagccacca
     5641 gcccggcggc gaatgtgctg gagacggtgc gtggtctgtt gcagcatcgc tcatttacca
     5701 tgagcaaccc gaaccgtatt cgttcgttga ttggtgcgtt tgcgggcagc aacccggcag
     5761 cgttccatgc cgaagatggc agcggttacc agttcctggt ggaaatgctt accgacctca
     5821 acagccgtaa cccgcaggta gcttcacgtc tgattgaacc gctgattcgc ctgaaacgtt
     5881 atgatgccaa acgtcaggag aaaatgcgcg cggcgctgga acagttgaaa gggctggaaa
     5941 atctctctgg cgatctgtac gagaagatca ccaaagcact ggcttgatac ttttgagcca
     6001 aaatgcctga tgcgacgctt gacgcgtctt atcaggccta caactccgtt gaaattgctg
     6061 gttttgtagg ctggataagg cgttcacgcc gcatccggca gccgtgccca actgcctgat
     6121 gcgatgcttg acgtgtctta tcaggcctac tagtccgttg aaaatgctgg ttttgtgcgc
     6181 cacatccggc atattaacca tgacgccgaa tcagttgttc agaatgccca cgccgcatta
     6241 cccgttgcaa tacttccgct tccagctccg ctaatcgcac cgaccctaat cgacgcggac
     6301 gggggatatc cactgtcaaa tccagaccaa tttttccctc ttcaattaac aacacccggt
     6361 cagccattgc taccgcttcg ctcacatcat gcgtcaccaa cagtacggta aagccgtgct
     6421 gctgccaaag tgacacaatc aaatcctgca tctcgagtcg cgttaaggcg tccagcgccc
     6481 cgagcggttc atcaagcaac aataaacccg gtcgatgaat caacgctctt gccagcgcca
     6541 cacgctgttt ctgcccgcca gaaagtgcgg caggccattc cccggcgcga ttctccagtc
     6601 ctactgcagc caacgcccga cgcgcggcat cgcgccactg gcctttaagg cctaacccaa
     6661 cgttatcaat caccgatttc cacggcagca gacgcgcatc ctgaaacatc attcgcgtgt
     6721 cttcctgaat ctcagccagc ggtgtggtgc ccgctaacac atcgcctgcg gttggcgttt
     6781 ccagacctgc cagcaggcgc agcagggtac ttttgccacc accgctgcgg cccaccaccg
     6841 ccacaaactg acctgccgga atatgtaaat ccagttggtt caggacgata ttttccgcgt
     6901 aatgtttgct tactgcattg agcaacaatg gtgtgccctg gttcagacga gcagtattca
     6961 taccgtggcc tccttcaaat gataagccgg gttccagcgc aaccagaggc gctctaacag
     7021 ctgcgcgctg acgtcagcaa gtttgccgag cagggcgtaa agaataatag cgactaccac
     7081 cacgtccgtt tgcaaaaact cccgcgcatt catcgccaga taaccaatgc ctgaattggc
     7141 agaaatggtt tcggcaacaa tcagcgtcag ccacatcagg cccaacgcaa aacgcacgcc
     7201 gaccataatt gagggcaggg caccaggcag gatcacatgg ataaacagcg gtatgccgga
     7261 taatccatag ctacgcgcca tttccaccag accgcgatcg atattacgga tgccatgcca
     7321 ggtgttgata taaatgggga atagcgtgcc gagcgccacc agaaagattt ttgcggattc
     7381 atcaatgcca aaccacaaaa tcaccagcgg gatcagcgcc agatgcggta cgttgcgcaa
     7441 catctgaatt gaggtatcca gcagccgttc tccccagcga gatagcccgc taatcagtcc
     7501 caaaatcaac cccagcgatc cgccaattga aaagccaatc agcgcccgcc aggaactgat
     7561 cgccagatgc tgccacagtt cgccgctggc ggagagcgtc cagaacgccg tcaccacccc
     7621 ttccggtgag ggcaaaatac gcgtcgacag ccagccaact gaggaggcca gttgccacac
     7681 cgccacgatg cccaccggta aaaaccaggg ggcaacgcgc aataaccact tcttcactgg
     7741 cgttgccatt atttcttcct tagctttgcg cgactttacg ggggataaaa tcattcgcca
     7801 ccgcttcgcc ttgcggattc agcggctgcg gctggggaat ttccggaatg gcgacatcca
     7861 gatgtgggaa cagcaactcg ccgacccgat acgcttcttc cagatgcgga tagcccgaaa
     7921 gcacaaagct gtcgatgcca agcgcggcgt attcgttgat tcgcgcagcg accgtaggac
     7981 catcgcccac cagcgccgtt ccggcaccgc cgcgcactaa gccaacgccc gcccataaat
     8041 tggggctgat ctccagattg tcgcgcttgc cgttatgtaa cgccgccatt cgctgttgtc
     8101 ctacggaatc cgtccgggcg aatgcggcct gtgctttggc gatagtttca tcatcaagat
     8161 gcgagattaa ccgctcggcg gcctgccacg cttcgtcgtt agtttcacga acaatcacat
     8221 gcagacgaat accgaaacga attttgcgtc catgcgcggc agctttcgcc cgcacttgtt
     8281 cgatcttctc ttttactagt tctggcggtt cgccccaggt gaggtagaga tcaacttgtt
     8341 ctgccgccag ctcctgggcg acgtctgacg atccgccaaa gtaaagcgga ggataaggct
     8401 gttgaatcgg cgggaagagc agttttgctc cgcgcacatg aatatgttta ccgttgaaat
     8461 tgacggtttc ccccagcaat aagcgccgcc agacctgggt aaattccgcc gaggcttcgt
     8521 agcgctcgct atgatcaagg aacacgccgt cgcctgccag ctcttgtgga tcgctgcctg
     8581 tgaccagatt aaacaacgca cgaccatttg agagacggtc aagcgtggcg gcctggcgag
     8641 cggcaacggt aggtgaggtt acgctggggc gcagggcgac aagaaacttc agccgctgcg
     8701 tcaccgggat catcgacgcc gccaccagcc acgcatcttc acacgatcgc cccgttggga
     8761 tcagcacacc ggtatagccc agacgatccg ccgcttgcgc aatttgttgc agatagccgt
     8821 gatcaaccgg gcgtgaacct tcttccgttc caagataatg cccgtcacca tgggtcggta
     8881 aaaaccagaa catattcaga ctcataattg ttttccttcc agttgagtgg gctgccagat
     8941 gcgctggcga atatcgactt ttttcggcac cagacgattt tcataaaaca gatctgccgt
     9001 ttgctgctgt aaggcggcaa cctcggcgtt aaccggtttg atggtggtag gagggcgatg
     9061 atctaagtaa gaggcaatca ccggtgccgg taagcccatc gtttttgcca gtaaagcgat
     9121 gctttgctcg cgctggctgc gggttaacgc atcggcctca ctaaaggttg cgagtacgcc
     9181 ctgaataaaa gcgccgtttt tttctgcata gggacgagct gccagataaa acgatccagt
     9241 ttgattgaga tcggtgccgt ctttcagcac ccgcacgccg ccctgtaata atgcagcaga
     9301 gtagtaggga tcccagatag cccaggcgtc aacgttacct tgctggaacg cggcgcgggt
     9361 atcagcgggc gtcaggtaag tgggttggat atcggtaaac ttaagtccgg cctgacgcag
     9421 tgcacgcagt aaaaggttgt gtgaactgga acctttctga aaggcaactt tgtgaccttt
     9481 aagatcggct acggttttga tcgggctgtt ttctgccacc agaatcactt cagctttggg
     9541 cttcggtggc tcgacgccca catataccaa atcagccccg gcagcctggg caaagattgg
     9601 cggaatatcc ccggtactgc cgagatcaat actgccaacg tttaacgctt ccaacatttg
     9661 cggacccgcg gggaactcca cccaggagat ttttgattgc ggatagcgtt tttccagtaa
     9721 ctggtggctt tttgccagta ccataccaat actgcctttc tgatagccta tacgtaacgc
     9781 ttcaggcgag gattctgcag caaccgcaat cgtagagacg ctaagcaatc ccaccagcgc
     9841 cagtttaatg atgttacgca tgggcattac ctcgcagaga cagaaggtca ggaacctgaa
     9901 catcgcggcg gtgcaatgcc tgccagaaag tttctagcgc ggtatcaaga cgggtttgca
     9961 gatttggcgt gaactggggt ctgtgatggt aatcaattac ttgtgagtca tcggcaaaca
    10021 cgccgtgcag gatctcctga gctttcagtg cgcttaaaac tggtttaagg gcataatcga
    10081 ccgccagcag atgggccacg gtaccgcccg tcgccagcgg tagcaccact ttgccttgca
    10141 aagcgcgctc tggcagcagg tcgagcaggg ttttcagcgc gccggaatag gcggctttat
    10201 acacaggtgt agcgactatc agtccatcag cctgttgcag ctgttcggtg aaggtcttga
    10261 gtgccggact atcgaaacga gcataaagca gatcttccgg ggcgaagttt tgcagattcc
    10321 agtgataaac ctctacatcg aggccattta gtttttcccg cgcatattcc agcaaggagc
    10381 tggagcgaga aggaaagcga ggactacccg ccagggtgat gacacgcata ctctctcctt
    10441 ataaccaatt gttctttttt tgttaacatt gataacaatt cggtcagtct gtcggagaga
    10501 caagaaaatg ccaaatataa attttgtgta tctttttctg aaaataaaca aaagaaaggg
    10561 ctttatatat cacgcatatt tatttgttgg atagtcatta gatgttgaat caatgaatta
    10621 ctcgttcagt taatatttaa atattcatga aatctataaa ttaaagattt gtcacttatt
    10681 ggatttagta tgcttgattt aaatggcggt caattattgt tattattaag tctaatgtca
    10741 tttaaaggca ttatcatatt tacgaagaga tcaggatgat gacgatgaaa aaaagtgtat
    10801 tgacggcgtt tataactgtg gtatgtgcaa cgtccagcgt tatggcagct gatgataatg
    10861 ctatcacgga tggcaaagta acatttaatg gtaaagttat tgctccagct tgtaccctgg
    10921 tagctgcgac gaaagattca gtagtcacat tgccaaatgt cagcgccacc aagttgcaaa
    10981 ctaatggagc agtctctggc gttaaaactg atgtaccaat tgccttagaa ggctgtgatg
    11041 ttactgtaac taaaaatgcg acgtttacct ttagtggtac ggctgacggc gtgcaaccta
    11101 cagcatttgc caaccaggct accaccgatg cagcgacgaa tgttgctcta caaatgtatc
    11161 tgccagatgg ttctacatcg gtaactcccg gtaccgaaac gtcgaatatt cagttagcgg
    11221 attctgctga gcaaacagtg acctttaaag ttgattatat cgctacgggg aaagcgactt
    11281 ctggtaatgt gaatgcggta acaaatttcc atattaacta ttattaatag aactcattaa
    11341 ttgttttatt aattagtacc cctctagtgt tctggagggg atattcatat tttttaagag
    11401 tgactattta tgaaaacttg cataacaaag ggaattgtga ccgtaagttt aacggcaata
    11461 ttactcagct gctcatccgc atgggcggca ggtaaaggcg ggattggact tgcagcaaca
    11521 cgtcttgttt attcagaagg tgaagagcaa atttcactgg gtgtacgtaa caccagtccg
    11581 gatgttcctt atcttattca gtcatgggtg atgaccccag ataataaaaa atcagcagat
    11641 tttattatta caccaccgct atttgtgctg aatccggcta atgagaatct gttacgcatt
    11701 atgtacattg gtgcgccgtt ggcgaaagac agagaaaccc ttttcttcac tagcgtacgg
    11761 gcagtccctt caacaacgaa gcgggaagag ggaaataccc tgaagattgc cacacaaagc
    11821 gtcatcaaac ttttctggcg accaaaaggt ttagcgtatc ccttaggcga ggctccggcg
    11881 aaactgcgtt gcacttcgtc agctgacatg gttacggtca gtaacccaac accttatttc
    11941 attaccctga cagacctgaa aataggtgga aaagtagtta aaaatcaaat gatttccccc
    12001 tttgataaat accaattttc tctgccaaag ggggccaaaa atagcagcgt aacgtatcga
    12061 accatcaatg actacggggc ggaaacgccg caactcaact gtaaatcgta agccgtcttc
    12121 agttaagaga gcgagatgta tagaactcat cgacaacaca gcctgttaag ctctggtgga
    12181 gtgccatcgt ttattggtgg gctggtggtg tttgtgtcgg cagcgttcaa tgcacaagct
    12241 gaaacctggt tcgatcctgc ttttttcaaa gatgatccct caatggtggc cgatttgtct
    12301 cgtttcgaaa aaggacaaaa aataacgcca ggggtttatc gtgtcgatat tgttctgaat
    12361 cagacaattg tagatacgcg caacgtcaat tttgttgaga taacgccaga gaaggggatt
    12421 gccgcctgtt tgacgactga aagcctggat gcaatgggtg ttaatactga tgcgtttccg
    12481 gcttttaaac aactggacaa acaagcgtgt gtgccattgg cggagattat tccggatgcc
    12541 agcgtaacgt ttaatgtgaa taaactccgt ctggaaattt cagtaccgca aatcgccatc
    12601 aaaagtaatg cccgtggtta tgtcccccct gaacgttggg atgaagggat caacgcgcta
    12661 ttactgggat attcgtttag cggggctaac agtattcata gcagcgcaga cagtgattct
    12721 ggcgacagct attttctgaa tttaaacagt ggcgttaatt taggcccatg gagattgcgc
    12781 aacaattcaa catggagtcg cagtagtggc caaaccgcag aatggaagaa tctcagcagc
    12841 tatttgcagc gggcggttat tccactaaaa ggcgaactga ccgtaggtga tgattatact
    12901 gcaggcgatt ttttcgatag tgtcagcttt cgtggtgtgc agctggcgtc agatgacaac
    12961 atgctgccag acagcctgaa agggtttgcg cctgtggtgc gtggtatcgc caaaagcaat
    13021 gcccagataa cgattaagca aaatggttac accatttacc aaacttatgt atcgcctggt
    13081 gcttttgaaa ttagtgatct ctattccacg tcgtcgagcg gtgatttgtt agttgaaatc
    13141 aaagaagcgg acggcagcgt caatagctac agcgtaccgt tttccagcgt gccattactc
    13201 cagcgtcagg ggcgaatcaa atacgcggtg acactggcga aatacagaac caatagtaat
    13261 gaacagcagg agagcaaatt tgcccaggcc acgttgcagt ggggcggacc gtggggaacg
    13321 acatggtatg gtggtggaca atatgctgaa tattaccgtg ccgccatgtt tggtctggga
    13381 tttaaccttg gcgatttcgg agcaatttcg ttcgatgtga cccaggcgaa gagtacgctg
    13441 gcagaccaaa gcgaacataa aggtcagtca tatcgttttc tgtatgccaa aacgctcaac
    13501 caattgggca ctaattttca attgatgggc tatcgctatt cgacgtcggg tttctacacc
    13561 ctttccgaca ccatgtataa acatatggat ggctacgaat ttaatgacgg tgatgatgaa
    13621 gatacgccga tgtggtcgcg ttattacaat ttgttttaca ccaaacgtgg caaactgcag
    13681 gtcaatatct cccagcaatt aggcgagtac ggttcgtttt atttaagtgg tagccagcaa
    13741 acttactggc ataccgatca acaggatcgg ctattacagt ttggctacaa cacgcaaatt
    13801 aaagatctct cgctgggggt ttcctggaac tacagtaagt cccgtggtca acctgatgct
    13861 gatcaggtgt ttgcactaaa tttttccctg ccgctcaatc tgttgctccc cagaagtaat
    13921 gatagctata ccaggaaaaa aaattacgcc tggatgacct ctaacaccag tatcgataac
    13981 gaagggcaca ttacacaaaa cctgggttta acggagacac tactcgatga cggtaacctg
    14041 agctacagcg tgcaacaggg atataacagc gaggggaaaa cggctaatgg tagcgccagc
    14101 atggactaca aaggggcgtt tgcagatgcc cgagtgggct acaactacag cgataacggc
    14161 agtcaacaac aactgaacta cgctctttca ggcagtttag ttgcccattc acagggcatt
    14221 accctggggc aatcgctggg ggaaactaac gtcctgattg cagcaccagg cgcagagaat
    14281 actcgtgtgg cgaacagcac cgggctgaaa actgactggc gcggatatac cgttgtcccc
    14341 tatgccactt cttatcggga aaatcgaatc gcacttgatg cggcatcgtt aaaacgtaac
    14401 gtggatcttg aaaatgcagt agtcaacgtg gttcccacca aaggggcgtt ggttctggcg
    14461 gagttcaatg cccatgcggg agcaagggta ttaatgaaaa catcaaagca gggtataccg
    14521 ctgcgttttg gcgcgatagc gacgctggac ggcatacaga ctaatagcgg cattattgat
    14581 gatgatggct cgctctatat gtccggtttg cccgctcagg gagcgataac tgtacgctgg
    14641 ggcgaagctc ccgatcaaat ttgtcatatc agttaccagc ttaccgaaca acaaattaac
    14701 tctgcgatta cgcgaatgga tgccatatgc agataatctt tggagaaaaa tgcgtgttat
    14761 tactacgact attttttgcc gccgtcttaa tgctatggtg cgctcaaact gctgcttata
    14821 gcgggcagtg tcataccact caggggaatc cgtatattgg cgtcaatttt ggcgttaaaa
    14881 ccctggagga agaagaaaat acggctggag tagttaaaga caaattttat cagtggaacg
    14941 aatcgaatga ttattatgtt tcctgtgatt gcgataaaga caatgtcaga agtggccgat
    15001 gggcattcgc cgcggattca ccgttagtct atttaggcga caactggtac aaaattaatg
    15061 actatcttgc cgccaaagtt ttattacagg ttaaaggcag ttctcctact gcggttcctt
    15121 tcgaaaacgt gggcacaggg gcagatacac gatggcatat ttgcgatccc ggcggtcaac
    15181 gtttaggtgg ccagggggct agcggtaata gcggtagctt ttccctgaaa atattgcagc
    15241 cgttcgttgg ttcggtcgtc attcctccta tggcgctggc gcgattattt gaatgctaca
    15301 acatacccgc aggtgattcc tgcacgacta caggtacacc ggttttagtg tattacctgt
    15361 ctggtactat caattcactt ggctcatgtt ccgtcaatgc cggagaaaca atcgaggtcg
    15421 atctgggcga cgtatttgcg gctaactttc gtgttgtagg gcataagcct cttggggcca
    15481 gaacggcaga acttgcaatt ccagtcaggt gtaacacggg aaacgcgggg ttagttaacg
    15541 tcaacctgag tctgacggca accacagacc ccagctatcc ccaggcgatt aagacgtcac
    15601 gtcctggcgt gggcgtggtg gtgaccgata gccagaacaa cattatttcc cctgctggtg
    15661 gaacattacc gctctctatt cctgatgatg cagacagtat cgcgcgaatg aatgtctatc
    15721 cagtcagcac gacaggtgta ccaccagaaa ccgggcgatt tgaagccacg gcaacggtga
    15781 gaataaattt tgattaacgc gtgaacgtat gaagaaaaaa acgatatttc agtgcgttat
    15841 cttgttcttt agcattctta acatccatgt cgggatggct gggcctgaac aagttagtat
    15901 gcatatttat gggaatgtgg tcgatcaggg ctgtgatgtc gccaccaaaa gtgcattaca
    15961 aaatattcat attggtgatt ttaatatcag tgattttcag gccgcgaata ccgtaagcac
    16021 tgctgctgat ttgaatatcg atatcaccgg ttgtgccgct ggtattactg gcgcggacgt
    16081 cctttttagc ggcgaggctg acacccttgc gccgacactg ctcaaactaa ctgacacagg
    16141 cggaagcggt ggtatggcaa cggggattgc cgtgcaaatt cttgatgcgc aaagtcagca
    16201 agaaatcccg ctcaatcagg tccagcctct tacgccctta aaagccgggg ataacacact
    16261 caaatatcaa cttcgttata agtccacaaa ggcgggagca acgggcggta atgcgacggc
    16321 ggttctctat tttgatctgg tttaccagtg aaggagtgat gttgaaacgg ataatctgga
    16381 ttctgttctt actgggatta acggggggct gtgagctatt tgcccatgat ggcacagtca
    16441 acattagcgg atcgtttcgc cgtaatacat gcgtgctggc acaggatagc aagcaaatca
    16501 atgtgcagtt aggcgatgtc tcgctgacac gtttttttca tgggaattat ggcccggaga
    16561 aatctttcat cattaatttg caggattgcg gaacagatgt cagcacggtt gacgtcacct
    16621 tttcaggaac ccccgacgga gtgcagagcg aaatgctgtc cattgaaagt ggtacggatg
    16681 cagccagcgg gctggcaatt gcgattctgg atgatgcgaa gatattgatt ccgcttaacc
    16741 aggcgagtaa agactacagc ctacatagcg gtaaggtgcc attaactttt tatgcgcaat
    16801 tgcgacctgt caatagcgat gtgcagtcgg gtaaagtgaa tgccagcgcg acatttgtac
    16861 ttcattatga ctaatacgtg gaacagattg gcgctcttga ttttcgccgt tttatcgctg
    16921 ctggtggcgg gtgaattgcg ggcaggagtg gtggtcggcg gaacgcgatt tatctttccg
    16981 gcagacagag aatcgatatc tattttactg actaatacca gtcaggaatc ctggcttatt
    17041 aacagtaaaa tcaaccgccc aacgcgttgg gccggggggg aagcgtcgac agtgccagca
    17101 ccattactgg ccgctccgcc acttattctc ctgaagcccg gtactacagg cacgttgcgc
    17161 ttgctgagaa cggaaagcga catcttgcct gtggatcgcg aaacgctatt tgagttaagc
    17221 attgccagcg tgccatccgg caaagttgaa aatcagagcg taaaagtggc gatgcgctcg
    17281 gtatttaaac tgttctggcg acccgaaggt ttgccgggcg acccgctgga agcttatcaa
    17341 caattacgct ggacacggaa ttcgcagggt gtacaactca ctaacccaac gccttactac
    17401 attaacctga ttcagttgag cgtaaatggt aaagcgttaa gtaatgcggg agttgtgccg
    17461 cctaaaagcc agcgtcagac aagctggtgt caggcaatcg caccgtgtca tgtcgcctgg
    17521 cgggcgataa atgattacgg cgggttgagt gcaaagaagg agcaaaatct gccctgaaac
    17581 aggttcggaa aacgtttgcg ttttttttgc cgcaggtcaa ttcccttttg gtccgaactc
    17641 gcacataata cgcccccggt ttgcacaccg ggaatccagg agagttcatg tactacccct
    17701 tcgttcgtaa agcccttttc cagctcgatc cagagcgcgc tcatgagttt acttttcagc
    17761 aattacgccg tattacagga acgccgtttg aagcactggt gcggcagaaa gtgcctgcga
    17821 aacctgttaa ctgcatgggc ctgacgttta aaaatccgct tggtctggca gccggtcttg
    17881 ataaagacgg ggagtgcatt gacgcgttag gcgcgatggg atttggatcg atcgagatcg
    17941 gtaccgtcac gccacgtcca cagccaggta atgacaagcc gcgtctcttt cgtctggtag
    18001 atgccgaagg tttgatcaac cgtatgggct ttaataatct tggcgttgat aacctcgtag
    18061 agaacgtaaa aaaggcccat tatgacggcg tcctgggtat taacatcggc aaaaataaag
    18121 atacgccagt ggagcagggc aaagatgact atctgatttg tatggaaaaa atctatgcct
    18181 atgcgggata tatcgccatc aatatttcat cgccgaatac cccaggatta cgcacgctgc
    18241 aatatggtga agcgctggat gatctcttaa ccgcgattaa aaataagcaa aatgatttgc
    18301 aagcgatgca ccataaatat gtgccgatcg cagtgaagat cgcgccggat ctttctgaag
    18361 aagaattgat ccaggttgcc gatagtttag ttcgccataa tattgatggc gttattgcaa
    18421 ccaataccac actcgatcgt tctcttgttc agggaatgaa aaattgcgat caaaccggtg
    18481 gcttaagtgg tcgtccgctt cagttaaaaa gcaccgaaat tattcgccgc ttgtcactgg
    18541 aattaaacgg tcgcttaccg atcatcggtg ttggcggcat cgactcggtt atcgctgcgc
    18601 gtgaaaagat tgctgcgggt gcctcactgg tgcaaattta ttctggtttt atttttaaag
    18661 gtccgccgct gattaaagaa atcgttaccc atatctaatt atttcttcga attcctcttt
    18721 ataagataat cagggcttta ttttcagccc tggttgtttt atattcatcg ctgttgctta
    18781 tttagacatt ttgtactttt attgttgagg ttattaagcg aagcgacaat ggattgtgtt
    18841 gctgcggttt tatagggtag gggagaggca gatgcgaatt aaaccagacg ataactggcg
    18901 ttggtattac gatgaagagc acgatcgaat gatgctcgat ttagccaatg gtatgctatt
    18961 tcgctcacgt tttgcgcgca agatgttgac tccagatgcc ttttctcccg caggcttttg
    19021 cgttgacgac gccgcgctct atttctcttt tgaagaaaag tgccgcgatt ttaatttatc
    19081 taaagaacaa aaagccgaac tggtgctgaa tgcactggta gcaattcgct atctcaaacc
    19141 gcaaatgccg aaaagctggc attttgtttc ccatggtgaa atgtgggtgc ccatgccggg
    19201 cgatgcggcc tgcgtttggt tgagcgatac tcacgagcag gtcaatttgc tggtcgttga
    19261 atctggcgaa aatgccgcac tatgcctgct ggcacaaccc tgcgttgtta ttgcgggtcg
    19321 cgcgatgcag ttgggcgacg ccattaaaat catgaacgac aggctgaaac cgcaggttaa
    19381 tgttgacagc ttcagcctcg aacaggcagt ctaacgcgcc aacttaagtg cagtcttcgg
    19441 tacacagcta cagcaaagaa tggtgccatc atcgcccatt gctgattttt ttagcggcgt
    19501 gacttcgcct tctaaaagct gaacacggca acttccacaa atgcccgcgc ggcaagaata
    19561 agggatacga attccctgat tttctaattg ctccagcaac acctgttggt tatttccacg
    19621 aaatgcctgt ccctgccagt caatatctac atttgcgtcc ggttgttgcg tgatgttggc
    19681 ggtatcatca gcggcagctg cgccgtaaat ttttgccgga gccgttgcca gaatttccac
    19741 ctcatcgcca acgcgaatca cgccgctatt acgggcaatt aaattctgac caaaatcgac
    19801 atcgccgtta tcctgggcag tgcggaaaga ttgcaatgtt tttaatggtt cgcctgccgg
    19861 atgtttttgc cctttttctg ggctgacggt ggtgaaaata cagcggctac aaggtttaac
    19921 cacatcaaac accacatcac caatgcgaat cactttccag ctatcttctt cccaggctga
    19981 cgcgccggaa accaccagat tggggcggaa ttgctccatt tttacactgg ccggacaacg
    20041 ttgttggaga tcacgtaacg aggcttcgtt agcaagaagg taaggatagc catcagcaaa
    20101 tgacaggggt acagtgttgt ggcgtttcac gcgccgggtc atttgtggcc ccacccagcg
    20161 taattgcact tcgcgggaga aaaatccact tagccatttg ttgatcgcgt ctggcgcaat
    20221 tcgcgcggta aaatgtgtgc cccaaacttc ggttggtgcg tcttgtgtgg cgaaatcagc
    20281 aaaacgaaca tatgcgctac tgccatctgg tgcggtgaga tgcaagccat catgcacagg
    20341 tgaaggagta aaccgtacca tctggggaaa ctggcgagcg gtaataaacg taccgtcagg
    20401 ttccgtgatc ataaagatgc gatcgaaggc cagaccactg acatcagcca gagcatgtgt
    20461 aagaccaatg ccgcgcatcg atttaacagg atgaataaaa agccgggtta atgtcaccac
    20521 ggtgcggtcc tcaaatgaaa ataagccctc aactttatga catgacgcgc ttattagcta
    20581 taatgcgcaa caattttctt agcgcctgtc ccattaggct attttatttg tcagtttggc
    20641 cctgggttgt gctcgaaatc ctcacgtact tgtgtacgct ccggtttctc cgcgctgtcc
    20701 atgtccagac tgactgcaac aattacgcct actgcggtag gctcttagag taaaagtgac
    20761 gatatgaatt ctctgtttgc cagtacggcc cgtgggctgg aagagctgtt aaaaactgaa
    20821 ctggaaaacc tgggggccgt tgaatgccag gtggttcagg gtggggtcca tttcaagggc
    20881 gacacacggc ttgtttacca gagcctgatg tggagccgcc tggcctcgcg tattatgttg
    20941 ccgctgggcg agtgtaaggt ttacagcgat ttagacctct atctcggtgt tcaggcgatc
    21001 aactggacag agatgtttaa tcctggcgcg accttcgctg tccacttcag tggtttgaat
    21061 gacaccatcc gcaacagtca gtacggcgcg atgaaagtga aagacgcgat cgtcgatgct
    21121 ttcacgcgga aaaatctgcc gcgtccaaat gttgatcgcg atgcgccgga tatccgcgtt
    21181 aacgtctggc tgcataaaga aaccgccagt atcgctcttg atctgagtgg tgatggttta
    21241 catctgcgtg gctatcgcga tcgtgctggt attgcgccga tcaaagaaac cctggcagcc
    21301 gctattgtga tgcgatccgg ctggcagcca ggaacaccgc tgctcgatcc gatgtgtggt
    21361 tccggtacgt tgctgattga agcggcgatg ctagcgaccg atcgcgcacc aggcttgcac
    21421 cgtgggcgtt ggggctttag cggctgggtg cagcatgatg aagatatctg gcaggaagtg
    21481 aaagcggaag cgcaaactcg tgcccgtaaa ggcctggctg agtatagctc tcatttttac
    21541 ggttcggaca gcgacgcacg ggtgattcaa cgtgcgcgca ctaacgcccg tcttgcgggg
    21601 attggtgaac tgatcacctt tgaggtgaaa gatgtcgcgc aactgaccaa tccgctgccg
    21661 aaagggccgt acggcacagt gttgagcaac ccgccatacg gggaacgtct ggacagcgaa
    21721 ccggcgctga ttgcgctgca tagcctgctg ggtcggatca tgaaaaacca gtttggtggc
    21781 tggaatctct ctttgtttag tgcctcgccg gatctgctaa gctgcttgca gctgcgtgca
    21841 gacaaacagt acaaggcgaa aaacggcccg ctggactgcg tacagaaaaa ttaccacgtt
    21901 gccgaaagca ctccagacag caaaccggcg atggtagcgg aagactacgc caaccgcctg
    21961 cgtaagaacc tcaaaaaatt cgagaagtgg gctcgccagg aaggaattga atgttaccgc
    22021 ctgtatgacg ccgatctacc ggaatataac gttgccgttg accgttatgc cgactgggtg
    22081 gtggtgcagg agtatgcgcc gccaaaaact attgatgctc acaaagcgcg tcagcgtctg
    22141 ttcgatatta tcgctgcaac catttcggta ctggggattg cgccaaacaa actggtgctg
    22201 aaaacccgtg aacgccagaa gggcaaaaat cagtaccaga aactgggcga gaagggcgag
    22261 tttcttgaag ttaccgaata taacgctcac ttgttggtga acctgacgga ttacctcgat
    22321 accggtctgt ttctcgatca ccgtatcgcc cgtcgtatgc tcggtcagat gagcaaaggc
    22381 aaagatttcc tcaacctgtt ctcttatacc ggcagcgcca ccgtgcatgc gggattaggc
    22441 ggtgcacgca gcaccaccac cgtggatatg tcgcgtactt atctggagtg ggcagaacgc
    22501 aacctgcgtt tgaatggcct gaccgggcgt gcgcatcgcc tgattcaggc cgattgcctg
    22561 gcgtggctgc gtgaggcaaa tgaacagttc gatctgatct ttatcgatcc gccaaccttc
    22621 tctaactcaa aacgaatgga agatgcgttt gatgttcagc gcgatcatct ggcgctgatg
    22681 aaagatttga aacgtctgct gcgtgcaggt gggacgatta tgttctcgaa caataaacgt
    22741 ggcttccgta tggatctcga cggcctggca aaactgggac tgaaagcaca agaaattacg
    22801 caaaaaacgc tctcccagga tttcgcccgt aaccgccaga tccacaactg ctggctgatt
    22861 accgcagcct aaaggaatag taatgtcatt aatcagtatg catggcgcat ggctgtcgtt
    22921 cagcgacgcg ccgcttctcg ataacgcaga actgcatatc gaagataacg aacgtgtttg
    22981 tctggtgggc cgcaacggcg cgggcaaatc gacgttaatg aaaatcctca accgtgaaca
    23041 agggctggat gacggtcgca ttatttacga gcaagatttg attgtagctc gtctgcaaca
    23101 ggatccgccg cgtaacgttg agggtagcgt ttatgatttc gttgccgaag gcattgaaga
    23161 acaagcggaa tatctgaaac gctatcacga tatttcgcgc ctggtgatga acgacccgag
    23221 cgagaaaaat ctcaacgaac tggcgaaggt tcaggaacag ctggatcacc acaacctgtg
    23281 gcagctggaa aaccgcatca acgaagtgct ggcgcaactg gggttagatc ctaacgttgc
    23341 gctgtcgtcg ctttccggcg gctggttgcg taaagcggca ttaggacgcg cgctggtgag
    23401 taatccgcgc gtgctgttgc ttgatgaacc gacaaaccac ctggatattg aaaccatcga
    23461 ctggctggaa gggtttttga aaactttcaa cgggacgatt attttcatct cccacgaccg
    23521 ttcgtttatc cgcaatatgg cgacgcgcat tgttgatctc gatcgcggca agctggtgac
    23581 ctatccaggg aattacgacc agtacctgct ggaaaaagaa gaagccctgc gcgtggaaga
    23641 attacaaaat gccgagttcg atcgcaaact ggcgcaggaa gaggtgtgga tccgccaggg
    23701 gatcaaagca cgccgtaccc gtaatgaagg ccgcgtacgc gccctgaaag cgatgcgtcg
    23761 cgagcgtggt gaacgtcgcg aagtgatggg taccgcaaag atgcaggtgg aagaggccag
    23821 ccgctccggt aagatcgttt tcgaaatgga agacgtttgc taccaggttg acggtaagca
    23881 actggtgaaa gatttttcgg cccaggttct acgtggcgac aaaattgccc tgattggtcc
    23941 gaatgggtgc ggcaaaacca cgctgctgaa actgatgctc ggtcagcttc aagcggacag
    24001 cgggcgtatt cacgttggca ccaaactgga agtggcttat ttcgatcagc accgcgcgga
    24061 actggatccc gataaaacgg tgatggataa ccttgccgaa ggtaagcaag aggtgatggt
    24121 taacggcaag ccacgccacg tattgggcta tttgcaggac tttctgttcc atccgaaacg
    24181 ggcgatgacg ccggtacgtg cgctttctgg cggtgagcgg aaccgcttgc tgctggcgcg
    24241 tttgttcctc aaaccaagca acttattgat tcttgacgaa ccgaccaacg atcttgatgt
    24301 cgaaacgctg gaactgctgg aagaactgat cgacagctat cagggcacgg tattgctggt
    24361 tagccacgat cgtcagtttg tcgataacac cgttacagaa tgttggatct tcgaaggcgg
    24421 cggtaaaatt ggtcgttatg tcggcggtta tcatgatgcc cgtggtcagc aagagcagtc
    24481 tgtggcgctc aaacagcctg cggtgaaaaa aaccgaagaa gccgccgcgg caaaagcaga
    24541 aactgtaaaa cgcagcagta gcaaactaag ctataaattg cagcgcgaac tggagcagct
    24601 accgcaattg ctcgaagatc tggaggcgaa gctggaagcc ctacagacgc aggtggcgga
    24661 tgcttccttc ttcagtcagc cacatgagca gacacaaaaa gtgctcgccg atatggctgc
    24721 tgcagagcag gagctggagc aagcctttga acgctgggag tatcttgaag cgttaaaaaa
    24781 tggtggctga tcgcaaaata gtcgatttaa acagagacag ctgacaacgg taaaattgcc
    24841 tgatgaactg ggtttatcag gcatgaaaac caacactttg ttagtcatct gtaaaatagc
    24901 gcatcattaa ggagtaccaa tgtgcgaaca tcatcatgcc gcgaagcaca tcctgtgctc
    24961 gcagtgtgac atgctggtgg cgttaccgcg ccttgagcat ggtcagaaag cggcatgtcc
    25021 ccggtgtggc acaacgttaa ccgtggcgtg ggatgcccct cggcagcgtc ccaccgccta
    25081 tgcgttggct gcactgttca tgctgttgct gtccaacttg tttccttttg tgaatatgaa
    25141 cgttgcagga gttaccagtg aaattacatt actggaaatt cccggcgtgc ttttttctga
    25201 ggactacgcc agcctcggca cctttttcct gttgtttgtg caactggttc ccgcgttttg
    25261 tctgataacc attctgttac tggtgaatcg cgcggaatta ccggtccgtt taaaagagca
    25321 actggcacgg gtgctttttc aactcaaaac ctggggaatg gcggagattt tcctcgctgg
    25381 tgtgctggtc agtttcgtta aactgatggc ttacggcagc attggggtag gcagcagctt
    25441 tctcccctgg tgtttatttt gtgtcctgca actgcgcgct tttcagtgcg ttgatcgtcg
    25501 ctggttatgg gacgacatcg ccccgatgcc agaactgcgc cagccgctaa aaccaggcgt
    25561 cacggggata cgtcaggggc tgcgttcgtg ctcctgttgt acggcaatcc ttcctgctga
    25621 tgaacccgtg tgcccgcgtt gtagtaccaa agggtacgtt cggcgtagaa acagcctgca
    25681 gtggacactc gcgctgcttg taacgtccat catgctgtat cttccggcta atattttgcc
    25741 catcatggtg gcggatttat taggctcgaa gatgccgtcg acgattctcg ctggggtcat
    25801 tctgttatgg agcgaaggct cttatcccgt cgctgcggtg atctttctgg ccagtattat
    25861 ggtgccaacg ttaaagatga tcgccatcgc gtggctgtgt tgggatgcca aagggcatgg
    25921 caagcgcgac agtgaaagaa tgcatttgat ttatgaagtt gttgagtttg taggccgctg
    25981 gtcgatgatt gacgttttcg ttatcgcggt gctctcggcg ctggtgcgta tgggaggttt
    26041 aatgagtatt tatccggcaa tgggtgcatt aatgtttgct ttagtcgtca taatgacaat
    26101 gttttctgct atgacgtttg acccgcgttt gtcgtgggat cgtcaacctg aatcagagca
    26161 tgaggagtcc tgacagtatg gaatctaata atggggaagc caaaatccag aaagtgaaga
    26221 actggtctcc cgtgtggata tttcctatcg tcacggcgct cattggggcc tgggttcttt
    26281 tttatcatta cagccatcag ggaccggaag tgaccctgat caccgcgaat gcggaaggaa
    26341 ttgaaggtgg caaaaccacc attaaaagcc gtagcgttga cgtcggcgtg gttgaaagcg
    26401 ccacactggc tgatgatttg acgcacgttg aaatcaaagc gcggctgaat tccggtatgg
    26461 aaaaattgct gcataaagac accgtctttt gggtggtgaa accgcagatt ggtcgcgaag
    26521 ggattagcgg cctgggaacg ctgctgtctg gagtttatat cgaactgcag ccaggcgcga
    26581 aaggcagcaa aatggataaa tacgatttgc tggactcgcc accgttggcc ccgcctgatg
    26641 cgaaaggtat ccgtgtgatt ctcgatagca aaaaagccgg gcagctctcg ccaggagatc
    26701 cggtgctgtt ccgtggctat cgggtaggtt cggttgaaac cagcaccttc gatacacaaa
    26761 aacgcaatat cagctatcaa ctgttcatca atgcacctta tgaccgactg gtgaccaaca
    26821 atgttcgctt ctggaaagat agtggcattg cggttgatct gacgtcagca gggatgcgtg
    26881 tggagatggg ctcattgaca acgctgctga gtggcggtgt cagctttgat gtgccggaag
    26941 gtctggattt agggcagcca gtggcaccga aaacagcttt cgttttgtat gatgatcaga
    27001 agagcattca ggattcgttg tacaccgatc acattgatta tctgatgttc tttaaagatt
    27061 cggtacgcgg tctgcaaccg ggagctccgg tagagttccg gggtattcgc ctgggtaccg
    27121 taagcaaagt gccattcttt gcgccgaata tgcgtcagac atttaacgat gattaccgta
    27181 ttccggtact gattcgtatc gagccagagc ggctgaaaat gcagcttggc gaaaatgcgg
    27241 atgttgttga gcaccttggc gaattgttga aacgtggttt acgcggatcg ctgaaaaccg
    27301 gaaacctggt cactggtgca ctgtatgttg atctcgattt ctatccaaat acgcctgcaa
    27361 taaccggtat tcgtgaattt aatggttatc agattatccc gaccgttagc ggcggcctgg
    27421 cgcaaatcca gcaacgactg atggaagcgt tggataagat caacaaactg ccattgaatc
    27481 cgatgattga acaggcaacc agtacgcttt ctgaaagtca gcgcacaatg aaaaacctgc
    27541 aaacgacgct ggatagcatg aacaagatcc tcgctagcca gtcgatgcag cagttgccga
    27601 cggatatgca gtcaacgttg cgtgaattga atcgcagcat gcagggcttc cagcctggct
    27661 ccgcagccta caacaagatg gtggcggata tgcagcgcct tgatcaggtg ttgcgagaac
    27721 tgcaaccggt gctgaaaacg ctcaatgaga agagtaacgc gctggtattt gaagcgaagg
    27781 acaaaaaaga tccagagccg aagagggcga aacaatgaaa aagtggctag tgacgattgc
    27841 agcactgtgg ctggccggat gcagctccgg cgaaattaat aaaaactatt accagttacc
    27901 tgtggtgcag agcggtacac aaagtaccgc cagccagggc aatcgtctgt tatgggtaga
    27961 gcagatcact gttcctgact atctggcggg gaatggtgtg gtttatcaaa ccagtgatgt
    28021 gaagtatgtg attgccaaca acaacttgtg ggccagcccg ttggatcaac agttgcgcaa
    28081 caccctggtt gccaacctga gtacgcaact gcccggctgg gtggttgcct cccagcctct
    28141 gggaagcgcc caggacacgc tcaatgttac cgtaacggag tttaacggtc gctatgatgg
    28201 caaggtcatt gtcagtggtg agtggctgtt gaaccaccag ggacaactga tcaaacgtcc
    28261 gttccgtctg gaaggagtgc aaactcagga tggttacgat gagatggtta aagtgctggc
    28321 cggtgtctgg agtcaggaag ccgcttctat tgcacaagag ataaagcgtc taccttaatt
    28381 ataaagattt gtaaatataa ccgtctccgg tatgttgcct gaggcggttt ttttgtctct
    28441 aacgtgcgga aaaatttgtt cctcttcaca ttttttgtac aaccgacatg cccgtgtagc
    28501 tcacaaatat gacagtggcg tgaattttgc gcattgacgg cagttatgat tcgcggtatt
    28561 gcttaactgt gattgcacat ttagtaatca ctgttttctt ttccaccaga aaccagtatg
    28621 agggaaacga ggcatgaaga gacaaaaacg agatcgcctg gaacgggcac atcaacgtgg
    28681 ttatcaggcc ggcatcgccg gacgctcaaa agaaatgtgt ccctatcaga cgctgaatca
    28741 aaggtcacaa tggctgggag gctggcgaga agccatggcg gacagggtag taatggcctg
    28801 attctgtctc tttaaaaaga aacctccgca ttgcggaggt ttcgcctttt gatactctgt
    28861 ctgattataa tcagaaggca gacgtatcct ggaacagacc gactttcagg tcgctggcgg
    28921 tatagatcag acgaccatca accagcactt cgccatccgc caggcccata atcagacgac
    28981 ggttaacaat gcgtttaaag tgaatacggt aggtcacttt tttcgctgtc ggcagtacct
    29041 gaccagtgaa tttcacttcg ccaacgccca acgcgcggcc tttaccttcg ccgcccagcc
    29101 agccgaggta gaaccctacc agctgccaca ttgcgtccag gcccaggcat cccggcataa
    29161 ccggatcgcc aataaagtgg catccgaaga accacagatc cggattgata tccagttctg
    29221 cttcaacata ccctttgtcg aagttaccac ccgtttcggt cattttgacc acacggtcca
    29281 tcatcagcat gttcggtgct ggcaattgcg ggcctttagc gccaaacagt tcaccgcgac
    29341 cagaggcaag aaggtcttct tttgtatagg attcgcgttt atctaccatg ttctctgtaa
    29401 gccttatttt attgaagcac gcaggatagc taacacgtgt acgctgaaca agtccgatca
    29461 gttcggaata aaccagttca gccaacgtaa tggccatgga aaacggtgac gtccttcctg
    29521 ttgcgatgct tgcgcgatac gttcctggat ggtttgcatc agcgtcgttt ggccttcgcc
    29581 atcccacacc agatttaata ataacggcag tgcgtcagtc acatcgtcta ctgcccagat
    29641 ggtgaatttg ccttcttcta ccgctttcac cagttcactg tgaagactta aatggcgaac
    29701 gttagctgtg gggataatga caccttgttt cccggttaac tcacgttgct ggcaaatagc
    29761 aaagaagcct tcgattttct catttaaacc accgaccggc tgggcgcgac cgaactgatc
    29821 gactgaacct gtgatagcga tactctgatt caccggcaca tcggcgaggg cgcttatcag
    29881 ggcgcagagt tcagccatcg aggcactatc tccatcaact tcactgtatg actgctcaaa
    29941 tgtcagcgat gctgagaagg ggatctgttg ctcaagctgt agttccgaca tcaggaacgc
    30001 ttgcatgatc atcatccctt tcgcatggat attgccgcca agctccgctt tgcgttcgat
    30061 gtcggtgaat tcaccatcgc caatatgcac aacgcagcta atgcgagaag gttcgccaaa
    30121 agcgcgtgga tgacccggaa attcaatgac cgaaagggcg ttaatttgcc cgatgcgttc
    30181 gccttcggtt tcaatcagga tttgctcctg aaggatctca tcctgcatac gttcagcgag
    30241 gaaaccttcg cgccattcac gctgctgcag cattaagttt agctgctcgc cggagaaggt
    30301 gtcgccatca cacagggagg cgacctcttt acactggcgg aggatccact gcgggctaag
    30361 cggaagtgtt tcttgttcac cggtgtagcg tgctgcttcg cggataagta ccggccaggc
    30421 atccgctccc ggtgcaggta agtgattatg tctggcggta aatgtcaccc agcgacacca
    30481 ctgggttact gactccgcat cgacaatctg cagagtatct tcaaattcgc tataaatagc
    30541 ctgctctgaa agctctggct ccatctcctg gaaatcagcc aatgattcgc gttcgcctac
    30601 cagaatgact ttcagcttca atggcatcga aggcacagag acggggagag ggcgcgactc
    30661 atcaaacgca acccagtcaa aacgctcgcg gttaacgata tttttcagcc gcatccacag
    30721 cagaggttgc gccagcagtg tacgcaaaga gatgatgaga ataccgccat ttgcctgatg
    30781 caccagacca ggctgcaggg taatgtcgcc attaaactgg cgcaggcagc caaagagttg
    30841 ctccgcttct acccagtcgg cagcgacaac ttgcgttaaa gtcgcaaaat tatcatctgc
    30901 actcactgcg tgacgtaagc ggatggagtg gccggaaacc tcatagtgac cgcccaccag
    30961 ttggcctgca tcgctttgta gcgtacgcgc ggcattggca ataagattca gatactcaga
    31021 ctcttccggg gccttcgcca gcataaaaga ggaggatgct cgcgtatgca gcaactgctc
    31081 cagtgcgaat tgcagtcgcg gttgagtatc actgaataaa ggatcgtttt cgtcaatcaa
    31141 atgtggctga gcaaatattt cctgatagct atcggtatca ggaaccaggt cacgccatgc
    31201 aagtttcgta atggtcaaag ttgatgtttt ttagtctgtt gtcaaagccg cgattatacc
    31261 gtaaccggca ctacagcaca cgtagaaagc accgacaata ctcctggcat gggcgttaaa
    31321 gctcacagga tggagattct tttcttcact ggcctaaaaa gctgatattc tgtaaagagt
    31381 tacacggtaa cattgagatc gctatgaaat atcaacaact tgaaaatctt gaaagcggtt
    31441 ggaaatggaa gtatctggtg aagaagcatc gcgaagggga gttaatcacc cgttacatag
    31501 aagccagtgc cgcccaggaa gccgtcgatg tgttgctctc gctcgaaaat gaacccgtgc
    31561 tggtaaatgg ctggattgac aagcatatga atccggaact ggtcaatcgc atgaagcaaa
    31621 ccattcgggc aagacgaaag cgccatttta atgcggaaca ccagcatacg cgcaaaaaat
    31681 cgatcgatct ggaatttatt gtctggcaac gtctggctgg tcttgcgcag cgtcgcggta
    31741 aaacgctttc tgaaacgatt gttcagctga ttgaagatgc ggaaaacaaa gagaaatacg
    31801 cgaataaaat gtcttctctg aagcaggatc tgcaggcatt gctgggtaag gaataactga
    31861 cgaaagtcag ttcaatttac taaaggcaaa aaaaaccccg cagcagcggg gtttttctac
    31921 cagacgagaa cttaagcttg cggctgagtt acaacgtctt tgataccttt aacttcgatc
    31981 tctacgcgac gatccggagc caggcagtcg atcagtgcag cacgctgttt cacgttgtca
    32041 caggtgttgc cagtaaccgg gttggattcg cccataccac gtgcggagat cttgtctgcc
    32101 gggatacctt tggagatcag gtaatcaaca acagactgag cacggcgctc ggacagaccc
    32161 tggttgtaag cgtcagaacc gatgcggtcg gtgtaaccca gaacaactac ggaaccgtct
    32221 ttcggatcca ggttgctcag ctggctgtac agctgatcca gagcagcctg accttccggt
    32281 ttcagggttg ctttgttgaa gttgaacaga acgtcagact tcagagtgaa gtgcttggtc
    32341 tgtacttccg gtgccggagc tggagccgga gcaactactg gagctgcttc gccctgaccg
    32401 aaacggtagg aaacacccag gctcagcatg ccgttgtccg gacgagtgcc gatggtgtgt
    32461 gcgtcaccga tgttgttggt ccactggtat tccagacggg tagcgatttc aggagtgatc
    32521 gcgtactcaa caccgccagc gaagaccgga gaaacgccgg tgtcgtggtt tttaccataa
    32581 acgttggatt tagtgtctgc acgccatacc ataccaccca gacgagtgta gatgtccagg
    32641 tcgtcagtga ttgggtaacc cagtttagcg gtcagttgaa cgccctgagc tttgtatgca
    32701 ccgttttcaa cgctgccttt gtacggcata cgacctaacc agtcgtaacc catttcaaag
    32761 ccaacatacg ggttaacctg gtaaccacca aaagcaccag cgcccagttg gttttcatgg
    32821 gtcgggccat tgttgttgat gaaaccagtg tcatggtact gggaccagcc cagtttagca
    32881 ccagtgtacc aggtgttatc tttcggagcg gcctgcgcta cggtagcgaa accagccagt
    32941 gccactgcaa tcgcgatagc tgtctttttc attttttgcg cctcgttatc atccaaaata
    33001 cgccatgaat atctccaacg agataacacg gttaaatcct tcaccggggg atctgctcaa
    33061 tattaactct accgatatct tcggcttatg ccgagcaccc ctggcgatgt aaagtctaca
    33121 acgtagttga aaacttacaa gtgtgaactc cgtcaggcat atgaaaaaaa agtcttgtat
    33181 aaggtatgtt taatcttttt tgtcagcgac aatttacaga agaaaatcgc ggaaaccgct
    33241 tcagacaagc ctccgcaagg aaaattagtc acgactgaaa gcattggctg ggcgacaaaa
    33301 aaagttccag gattaatcct aaatttactt aatgatacaa attagagtga atttttagcc
    33361 cggaaagttg tctcgtggcg tgagaggatg cgcttaccgg acgcataata aaccccatag
    33421 cgttaccttc atttgccgca tcaacaagtt cagcatgctc ttcttcagtc aaatcatctg
    33481 ccaaccaacc gatcaccaca ctgtaattgc ccgtgcgtaa agcgcgaacc attgactcca
    33541 cagtgtggca aggggagagc tggctaatct gcattacttt cgttaagggt agcccagatg
    33601 cctgaaccca ttcccgactc agtttttgtt gcggtgttaa ccagagttgc cagcgcgatt
    33661 gctgaccgag ttgctgtaac aatggcaaca gtagaagttg cgtcatcatg ggctgatctt
    33721 cgcgatagac aacttcactg ataagcccgg ctgtagtgtt ttccgtagag acacgcgcaa
    33781 ttttacttgc tgcggatgag aacgacgaag aacgatgtgc atagcctgaa gtgtacataa
    33841 tcaatccagc ccctgtgagt tactgtatgg atgtacagta catccagtga caacaaagat
    33901 caaccctatt ttcggaaaga gcctcgcaaa ttttgtcgtt ggtgacggga aaacataaat
    33961 taatcttgcc ccttaagaat aagttgccta ttttcgtagt taacggatcc gttaatgtga
    34021 atcattcttt tatgttatga ttttaaaagg aattttatga aaagcctctc ctataagcgg
    34081 atctataaat cacaagaata cctggcaacg ttgggcacaa ttgaataccg atcattgttt
    34141 ggcagttaca gcctgaccgt tgacgacacg gtgtttgcga tggtttctga tggtgagttg
    34201 tatcttcggg cttgtgagca aagtgcacag tactgtgtaa aacatccgcc tgtctggctg
    34261 acatataaaa agtgtggccg atccgttacc ctcaattact atcgggttga tgaaagtcta
    34321 tggcgaaatc aactgaagct ggtgcgtctg tcgaaatatt ctctcgatgc agcgctgaaa
    34381 gagaaaagca cgcgcaatac ccgggaaaga ctgaaagatt tgcccaatat gtcttttcat
    34441 ctggaagcga ttctcgggga ggtggggatt aaggatgtac gggcgttacg tatacttggg
    34501 gcaaaaatgt gttggttgcg actgcggcag caaaacagtc tggtgacaga aaagattctg
    34561 tttatgcttg aaggtgccat tatcggcatt catgaagctg cgctcccggt ggcacgccgc
    34621 caggagcttg cagaatgggc tgactctctt acgccgaaac aggagtttcc tgcggaactt
    34681 gagtaatctg gcgttgcaga cgaccaatct caggcagtaa tgcaatcaat aatccaactt
    34741 gttgtacgac cagaggttct ttgctgtctg cccgtggttc aagttgctgc atccgctgtt
    34801 tcaggctagc taatgcctca ttgacgcgtt cttcatcagc aggttgatga tgtaacgcgt
    34861 catcaacata gcaaactgcg tcatcaagaa acgccagaat ttcaggatta gttaactgct
    34921 cccggtgagc accgagggct gagatatagc tggtaaacgt atggttaagg cacagcaacc
    34981 gaaacgcggc ttcgcgaatt tgcggggtaa cgttcggttc gctggacata tttgatacca
    35041 ccgacgccag ttcagcatca cggttgtgtg catcgcggcg ggcaatacga tacgccagac
    35101 ggttatcacg cccctgatgg tattgctcca gtatggcatc gagataccgg cagttggcct
    35161 ctgtggcgcg ttcgagcatt cgcggcagat tgcgaaactg ccagtcaggc cagatgtagc
    35221 tcactgccgc ccacgcaatg gcacaaccaa tcagcgtatc gattacgcga ggtaacgcta
    35281 cttcaaaacc ttcacccagc aagttaaaac acagtagcac caaaagtgtg atgaacatcg
    35341 ttgcatgggc atattgcacg ttacggaagg caaaaaagag cacgccggta ataaccagta
    35401 gcaccagctg cccttccagt gacggtacaa accacagcac aggaatgcca atggcgatac
    35461 cgaccagcgt accaataatc cttaacttca ggcggtggcg cgtggcgtta tagtttggct
    35521 ggcagacaaa caaacttgtc agcaagatcc aatacccgtg atgcattccg gttatctgaa
    35581 tgatggcgta gccgaagcac aacaccagcg acattcttac cgcatgacgg aagagggcgg
    35641 attccggcgt gaagtgacgg ctaagacgca gccagatatc actcaatccg tgcgggctat
    35701 catcagcgag ctcattttcg tcattattat ggggcagtgc ctgggcctgt tctgattcaa
    35761 ttgttgccag ttgggcatca atggcgcgta aattgttcag caaaaatccc agtgttttaa
    35821 gtaaatcggc aggcgcgccg ttatcgcgca tccgctccag cgcagcatca atatgcgtaa
    35881 aagcgcgctc aaaatgcgga tcatgttgat aaggctgacg cagcaaaata cagcgtgaca
    35941 gttgctggca cgcctggccc tgcatcgaca tcagccgctg aaaacggaac agcacgtcgc
    36001 tgtggcgaaa atgttcacgc aatgtttgat actgaatatg agaagagctg gcacgctcgt
    36061 gaatatcctg tgcgacaaag taataatgca gcgtgcgacg cgttccccgt tgaccacgat
    36121 cgccacgtaa gcgggtcagc agcgagagtt tcgtctgatt caatgtcgcc atcagctgac
    36181 cgttggcgag agccaaatcg tacagcggtg cctggctttc atcttcaata tcaggatcaa
    36241 acatgcgcga cttgagctca agataacgcg ccagttgttc atagcaacgc gccaggttgt
    36301 cctgcagcgg gcggaccggg aacagcagat gaccaataag tgtcaggacg ttgtaccaga
    36361 cggcaccggc cagcagatac atcggctgct gataccagtg ctcatacagt gatgttccca
    36421 acatagtgta aatggcgatc agcaatgcac cgaaggcaat tgttgcatag cgttgaccca
    36481 gaccgccgag caaaatgaag ccgctggtag agagcgttaa gccaatcgca aatagccagg
    36541 gccagggaaa cagcaattct actgaggccg aggcgataaa aaagcagaac agcgtaatga
    36601 tgaggttacg caaacgtccc gccagtcggt catcgagatc ggtcagcgcc gctgccacca
    36661 tccccagcgt tagcggaatc gtcagtttta catcacccag ccaccacgga aacgctgtgg
    36721 ttccacaaag cgcaataaaa atacgcgcgt aatacagcca ggcgctgttc caggtatagc
    36781 gtttgagcaa aggacttagc ataaaggcca tattagtgga ttattcaaaa cgacgacgtg
    36841 cattggcttc acgcgcagct tgcgccgttt ctaccgatac cacgcgacga ccaaccggcc
    36901 atagtgcaat agcggcaatt ttaaagttcg caatgccgac aggaatgcca atgattgaaa
    36961 tacattgtgc gatgcccgtt gcaatgtgca tcaggcataa ccaccagcca aagaaaatca
    37021 gccagaaaat attcaatacc gtaccgccag tattcagcag cacatttttg ccagccgggt
    37081 tcagttcatc gacatgaata gcttcattgc cataaggcac cagagacagt ttagtgatct
    37141 cccagcagga tcgtgtcagc ggtaaggtaa aaatcagcat aatactgacc agagtcgcca
    37201 acagccagcc cagagtggtg gcaaatccgc caagcacaaa gttcagaatg ttcaaaacgg
    37261 tacgcataaa acctcgcttt actgtggttt tcagtaatgg gcggcaattg taacgttttt
    37321 ttgggctgga gcacgttttc tctgacggtt acactgataa gaaataattt cgtgtggatc
    37381 tacagagtca tggaactgaa agcgacaacg cttggaaaac gtctggcaca gcacccttac
    37441 gatcgggcgg tgatcctcaa tgccgggatt aaagtctccg gcgatcgcca cgaatacctt
    37501 attcctttca atcaattact ggcgattcac tgtaagcgcg gtctggtatg gggcgagctg
    37561 gaatttgtac tgccggacga aaaagtggtg cgtctgcacg gcaccgaatg gggcgagacg
    37621 cagcgttttt accatcatct tgatgctcac tggcagcggt ggagtggcga gatgagcgaa
    37681 attgcgtctg gtgttttacg ccagcaactg gatttgattg ccacgcgcac tggagaaaat
    37741 aaatggctga cgcgtgagca aacctctggc gttcagcaac aaatccgcca ggctatgtcg
    37801 gcgttgccgt tgccggttaa ccgactggaa gaattcgata actgccgtga ggcgtggcgt
    37861 aaatgtcagg cctggttgaa agatattgaa agcgctcggt tgcagcataa ccaggcgtat
    37921 accgaagcca tgcttaccga gtatgcggat tttttccgcc aggtcgagtc ttcaccgctg
    37981 aatccggcgc aggcccgggc agtcgttaat ggcgagcatt ctctgttagt gctggcaggt
    38041 gcaggaagcg gaaaaacgtc ggtgctggtg gcccgtgcag gctggttgct ggcgcgtggt
    38101 gaagcgtccc ctgagcaaat tttattgctg gcgtttggtc gcaaagccgc tgaagagatg
    38161 gacgagcgta ttcgcgaacg gctacatacc gaagacatta ccgcacgcac gtttcatgcg
    38221 ctggcgctgc atattattca gcagggcagc aaaaaagttc cgatagtcag caaactggaa
    38281 aatgataccg ctgcccgtca tgaactcttt attgctgagt ggcgcaagca atgcagcgaa
    38341 aagaaagcgc aggcgaaggg ctggcggcaa tggctgacgg aagaaatgca gtggtcagtg
    38401 ccagaaggta acttctggga tgatgaaaaa ttacagcgtc gtcttgcatc acgcctcgat
    38461 cgttgggtaa gtctgatgcg gatgcacggt ggtgcacagg cagaaatgat tgccagtgca
    38521 cccgaagaga ttcgcgatct gttcagtaaa cgtatcaagt tgatggcccc gttattaaaa
    38581 gcctggaaag gtgcgctgaa ggcagaaaac gctgtcgatt tttcgggcct tattcatcag
    38641 gcgattgtga ttctggagaa aggtcgcttt atcagcccgt ggaagcatat tctggttgat
    38701 gaatttcagg atatctcgcc gcagcgggca gcgttgttag cggcattacg caagcaaaac
    38761 agtcagacga cgttgttcgc cgttggtgat gactggcagg cgatttaccg attcagcggt
    38821 gcgcaaatgt cgctcaccac cgctttccat gaaaactttg gtgaaggcga tcgctgtgat
    38881 ttagacacga cttaccgttt taacagtcgt atcggtgagg tggcaaaccg gtttattcag
    38941 cagaacccag gccagttgaa aaagccgcta aacagcttaa ccaatggaga cgaaaaagcc
    39001 gtcacgttat tggatgagag tcaacttgac gctttgctgg ataagctctc tggttatgcc
    39061 aaaccggaag agcgcattct tatcctggcg cgttaccatc acatgaggcc tgccagcctg
    39121 gaaaaagcgg caacacgctg gccgaagttg caaatcgact ttatgaccat tcatgccagc
    39181 aaagggcaac aggcggatta cgtcatcatc gttggcttgc aggaggggag tgatggtttt
    39241 ccggctgcgg cgcgggagtc gattatggaa gaggcgctac tgccaccggt tgaggatttc
    39301 ccggacgctg aagaacggcg gttaatgtac gtggcgctga cccgggcacg ccatcgggta
    39361 tgggcactgt ttaacaaaga gaatccctct ccctttgtgg aaatactgaa aaatctggat
    39421 gtgccggtag cgagaaaacc gtaagaaaca ggtggcgttt gccacctgtg caatattact
    39481 tcagacggtc cgcgagataa cgctgataat cggggatcag aatatcgacc gcgtcgttga
    39541 aatgcggcga ctggattatg aagtctgccg ttgccacgtt ggtggcgacc ggaatgttcc
    39601 ataccgtcgc cagacgcaac aaggctttca cgtcaggatc gtgcggcacg gcatttagtg
    39661 ggtcccagaa gaaaatcaat acatcaattt tcccttctga gatcaatgcg ccaacctgct
    39721 ggtcaccccc cattgggcca ctcaacatcg cgttgacgtt catgccggtc gcgcgggaaa
    39781 ttaagttacc ggtagtgcct gttgcataca gtacgtgttg ttccagtaac ggttgatgcc
    39841 gttccaccca gctcatcagc atttgtttgc agtgatcgtg tgccaccagc gcaatatgtt
    39901 tccgcgcagg taaagtgcga gtcgtcagtt ccataatgta catccgtagt taactttcct
    39961 acagattact gtaagcactt atcgctgcaa gataaagacc gaaaaagcct gcgcacaggc
    40021 acaaaaatct caggaagatg gttgtttttc cgcccattgt aggaaagtat ttcgcgtttg
    40081 tgggtcagcc agtttaaacc aatacttcag ccgttgttct gtgagcacct gagactgcgg
    40141 tggaatagca tccagctcgg aaacacccga aagcagcgta ctgtcatctg ccatcatcgt
    40201 ggcaaattgc ggtagtgaag cgcgtttcgc ggatttgtta tagcgttcaa cctcgacctc
    40261 ataatcaatc gtttttgccg ttgaggtaat ggcgagaata tccagcttta ccggaatcgg
    40321 cgtcgcatcg ccatccaaca attcaaggcg cggcgcggca tcaaaatggt tagcttcccg
    40381 ctcattctcc aggcgaggca ggcgaaaatt gacctggttg atgagctggg tattaaaact
    40441 gaccaccagc ggtggggaga tatacagccg ttcttcacta ttggaaagat gaatcgtctt
    40501 ctcaacgcga aacactaact gatgcggtcc attatccagt tcaatgctgt ccgcaccgcg
    40561 cagcagagag ctggaaacct tcttgccgtc gagtaccaga agatcgacat cggttgaaag
    40621 ccgcagcgtg gtggcaaaaa cggataccgg caaacataat gcaatcaagg tggtcacgat
    40681 gccggttttc ataggtagct cctgtcaaaa gaccgcccga ataataatgt gtcaaaattt
    40741 ttctttaatc atacttacta acatatagac atatttcccg cttttgctct caatcattcg
    40801 tattagctgc atggttggca tgtcggcttt gtcgtacact ttgttaaaca gtctggagga
    40861 aataatgaaa gaaaccgata ttgcaggtat tttaacgtcc actcacacca ttgcgctggt
    40921 gggggcaagc gacaaacccg atcgtcccag ctatcgcgtg atgaaatatc tactcgacca
    40981 ggggtatcac gtcattccgg tttcgccaaa agttgccggc aaaacgctgc tgggccagca
    41041 ggggtatggc acgctggcag acgttccgga aaaagtcgat atggtcgatg ttttccgtaa
    41101 ttcagaagcg gcgtggggcg tggcgcagga agctatcgcc attggcgcga aaaccctctg
    41161 gatgcaactg ggggtgatta atgagcaagc ggcagtactg gcacgggatg ccgggttaaa
    41221 tgtggtgatg gatcgctgcc cggctattga gatccctcgc ctgggcctgg ccaaataaaa
    41281 aatccccgga aggcaaaaac cttccgggga tttgttcagg gattagttac gcagacgcgg
    41341 ggcctggagt tgtttgcgga tggtctgcgc cagctcatcc atggatggct gttcaggatg
    41401 ttcatcctgc aattcgctac ttagctgggc ttcagccagg taggtatgaa ccggtaggcc
    41461 gttatcgtcc tccatcacca cgtgatacca cggagcggcg cgaagctcgt cattcaccgc
    41521 cagttcatca ggcgatggtt cagagagcga ataaaccggg tcgatatcca cgaccactcc
    41581 gagataacct aacagggaat ggcggacctg ctggccgata ccgaatttgc tggcaatcat
    41641 agtcacctcc cgggaaatct ttacctttga tataagggta aaattccaca tttcaagtta
    41701 catgacgcga caggcaaacc ctttcagata tagcccttcc gggtaggtag cgatcaccgg
    41761 atgatcggct gcctgacgga actgctctat aaattgtaca tcacggccgg catcaattgc
    41821 ggcatccgcg atgattttct gaaataaatc gctggtcatc agaccggaac aggagaaagt
    41881 caggagaata ccgtcttcat tcagcaactg aatcgccagc atgttgatat ctttatagcc
    41941 acgacacgcg cccatcaact ggcttttatt ctcaacaaac ttcggcgggt ccatcacgat
    42001 aacgtcaaat ttttcaccgc gatcgcgata agtacgcagc aatttaaaga catcatcacg
    42061 gacaaactca gccttgctca gatccagttt gttcagctca acgttctgcc gtgcaatatc
    42121 cagcgcttcc tgggaggtat caacgctgac aacctggctg caaccgccca tcagtgccga
    42181 tacggcgaaa ccaccggtat aggagaaaca gttcagcaca cgtttatttt caacgtagcg
    42241 gcgggtagcc aggcggctgt ctcgctggtc caggtagtag cccgttttgt gtccgtgctg
    42301 aatatccacc agcagcttca tgccgtgttc ttcaatcggc agcagggcag gcggcaactc
    42361 gccggtgacg gggccttggg tcagctccat cccttctttt ttacgtaccg caacatcgct
    42421 gcgatcgtaa atcgcacatt ccgggtacag cgtttgcagg gcactaatta atgccgcgcg
    42481 ctgatactct gccccagcac tcagcagttg cagcaccaga aaattaccga aacgatcgat
    42541 agtaataccc ggcaggccat cagattctcc ggcgattaaa cgatagctgt cgaggccatc
    42601 tttttgcgcc agccagtcac gccatttttg tgcttgttgc aaacggcggg aaaaaaaagc
    42661 aatgtcgata gactcagacg ggtcaaacgt ccagacgcgc gcccggattt gcgaagctgg
    42721 cgaataagcg ccgcgtgcta accattttcc ctgatgatca acaatatcga tggtttcacc
    42781 gaggctggct ttaccttcca tgcgggcaac ggccccggaa aagacccacg gatggcgacg
    42841 aagtaatgat ttttcgcgcc ctttggctaa cactaaacgt acactcataa tttacttttc
    42901 tgtcgatgca aagaaatggg cgtcattgtc cggagttttc catggatttg caacgcgtcc
    42961 attaaggata aggagagcag caatgtcgaa agtctgcata attgcctggg tttacgggcg
    43021 agttcagggc gtaggatttc gctacaccac acagtacgaa gcgaaaagac tgggtttaac
    43081 cgggtacgcc aaaaatcttg acgatggcag cgtggaagtg gttgcttgcg gtgaagaagg
    43141 gcaggtagaa aaattagtgc agtggttaaa gagtggcggc ccgcgttctg cgcgtgtaga
    43201 acgggtgctc agcgagccgc atcatccctc gggggaatta accgattttc gtatccgtta
    43261 aatacatttt accggttttg gcaggccagc aattttggtg gcttgcttag ccggaccttt
    43321 cggaaacagt cggtataaat agcggctgtt acctttttct tcgccaaatt tattcgccat
    43381 cgcttttacc agcatacgaa tcgccggaga agtattgaat tccagataga aatcacgcac
    43441 aaaacgcacc acttcccagt gttctggcga cagcgaaatc ccttcgttct ttgcaatcac
    43501 cactgccagc ggttcactcc actggctgct ttctttgaga tagccttcgg tatccgtttc
    43561 tatctcttta ccttcgaaga tcagcataat tattactacc ttaatcagac tggcggcagt
    43621 gtaacaaaaa acaaagcccc gcataaagcg aggctatgaa agtgttagcg ggtgagatta
    43681 atcgcggctg gcgaagccca gaatgctcag caggctgacg aagatgttgt acagcgaaac
    43741 atacaggcta accgtggcac gaatatagtt cgtttcaccg ccatgaatga tgttgctggt
    43801 ttcaaacaaa atagcgccag aggagatcag aatgaagacc gcgctgatcg ccagatgcag
    43861 agcaggcagt tgcaggaaga tattagcaac cataccaatc agtaccacca caatacccgc
    43921 catcagcata ccgccgagga acgacatatc tttgcgggtg gtcagcacat atgcagagca
    43981 gcagaagaac actaacgccg ttccgcccag tgccatagcg attacgtcac ccattccggc
    44041 agacagatag gtgttcagaa ttggtccgag gatataaccc agaaaaccgg taaaggcgaa
    44101 tgcggagata atcccggtcg gcttattcgc cgttttatag gtcaggaaca tcaaaccata
    44161 catacccacc agcgtcagaa tcagacccgg agatggcagc atcagcaccg tactggcagt
    44221 tgcggtaatc gccgaaaagg ccagcgtcag gctcagcaga aaataggtat tacgcagcac
    44281 cttatgggtg ctaagcagtg atgtacggtc atgtgaagaa ctaacaatac gatccattga
    44341 gtcactctct atgacagatg taattaatta agcagcataa tgataatgcg taagggcacc
    44401 cagaagtttt acccatcttt acgcatttga tctggaacag gtttaacagc ggattatcag
    44461 gtcattaagc aaatataacg ccctgagaat ttcgacaggc aaaagaaaaa ggggttagca
    44521 tttagctaac cccttatctt atctggcgga agcgcagaga ttcgaactct ggaacccttt
    44581 cgggtcgccg gttttcaaga ccgaagaaaa acaaataaaa atcagtgtaa tacgtgaaat
    44641 tgctgaaaag ttaatcaaat ttaacaccaa gaaaaatcaa ggtattagga agttgctcat
    44701 agctagtata ccaagtcttt ttgccagaaa tttttctgga ttgtctactt gctaaccacg
    44761 agcggcaaat ccagtgttgg tgtgattttt gttttacgat cgtaaatcaa cacctgattt
    44821 tctgttttat gcccgctgaa aatttgtttg tcgcgactgc tgccttcgta atctgagatc
    44881 cccttggctt ttatgtcgtg aaaattgcac ccgaacggaa cgccaacttt ttgctcggct
    44941 gcgcgtttag cctgattcca ccagttattc agcgttttag ctatgacttt cccgcctttg
    45001 gttgtattga tcacatattc gcatgtacag gaagatacat ttcgggctaa ctggatcgct
    45061 gtacgtaatc gcggtgacca ttccttgatt tgtttggtgc cggttttgtt ttgctcaatg
    45121 tagatccctt tatccataat atcctgccat ttcaactcaa gcacatcacc gagtcttgcc
    45181 gcacagagat aggaaatctc cattgcaatg cgtaactgtg gaattgcttc cgcatatatc
    45241 gccgcatact gttcatcggt gatgtaaaca gtgcgggctt taagagagaa ttttctgact
    45301 cctttgcatg ggttattctt cacataccca cgctcatatc cccacccgta tactcgactc
    45361 aggcttgcca gttcatgatt tgcctgggtc ttgctctcaa gccctcgttt atccatgaaa
    45421 attcttacct gctcagtttt gacattatca gcaagcactt ttccgaatac catcagcaac
    45481 gccttctgat gttgtcgata atctttttgg gttcgggggg ccagttctgt aaatgcaggg
    45541 gagtccataa acatgtgcca caatttagct acggtcatta tgttgtggag ttttgctttt
    45601 tccagttcat aattttgcca gactttagct acgctggttt tccgcactct tcctagccct
    45661 atacttcttg tacttccttc gggtttccac acgtaactgt aaccattcga tctaacccgc
    45721 ggtggcagta cattatcttt tttatttttt cttggtcttc ccattgttca gcgcctcaaa
    45781 atcgggttca gcagaaacca gttcagatgt ttttggcatc gttgtcagac cgtgtggaat
    45841 atccctgcgg agaactatgg gttcgttttt agggccgatt acaaatggga tgccgtgcag
    45901 tcttaactgg tgttgctgtt ttgtgtatcg ctcgtatttc gtgatctctt taatctctgc
    45961 tggagataga gttaattcgt acatgtggtc acgtgccttt acagcatgac cgccgccact
    46021 atagctggtg ggcggcgata tgggttgaac atcaaaaatc agcctgactc gggagcagtt
    46081 tttgccagat ggctgaaacg tatttcgcct ggtaacgtgc atcgttcaga gcgttatggc
    46141 gttcaccttc gaatggaata gtcgttcttg cgtcgaaatc catcaccagt cccagagcaa
    46201 ccatcgttct tacatcgcga tcattggtgt aacgccatgg gcaggggatc ccctgccgtt
    46261 catatgaacg gcgtaaaatc acgttgtcga aagttgcacc gttaccccag acctgaacaa
    46321 aaaattcacc ggagttttcg tcgataaatt cccgtaattg cagcagtgca tcatctaacg
    46381 ggatttcatc ggtaagaatg gcggattgcg cttcgcgtga ctgtttcagc caccacttaa
    46441 tggtgtcccg atcaatgact ccgccagcag tttccagatc gatagttttg ctgaattctg
    46501 gccccatctc tccggtttgc ggatcgaaaa atattgcacc tattgagata atcggggcat
    46561 caggattttt tcccattgtt tcaaggtcaa tcatcagatg gtgccacaac ctgctggtgg
    46621 atgagatttc atgatgaccg ttcactttaa ttaagggatt tgctgtttcg ccagttttat
    46681 tatcgctggc gtgatactga tcgctgccag tgttctcctt gtgcagatgt tcagtgcctt
    46741 ccatttcctc cggatcattt ttctgagctt cagcctgatt ctcttcatcg aatgtttcca
    46801 ggtaggttgc gttccccatc accgcaccac agtcaggaca gttgccgcca ccggtctgac
    46861 cgcatgcggt gcaaactttt tccagttcct gttgcactgc tggttctggt tgttgttctt
    46921 ctggcccgtt ttgttgcgta tccgggctgt tttgttccgc ttctggctca ttttgtttca
    46981 cgttgggctg attctggtcc tcagcgtcgc gactctggat ccctttcacc catttcggat
    47041 cattcgggtc gctaatccct tcaacaaatt caccacgtga tgcagcaagc aatttatcgg
    47101 cgtcaggctg gctgatattg gctgcctgca taattttgtt tacttcgtca gcggtaactt
    47161 ttaccggctc tgattgttcg gaatcttcag cggtatccac attttgcggt aagcccgtgt
    47221 atgtgccatt ttttcgggca aaatattctt cttttgagat ttcggtaccg ccggcagcca
    47281 gcgccttgtc cagaccagaa agtttgtttg ccctgccgta tttttccccg cccttatcgg
    47341 taaagacgaa ataaaatggt ccttcacgct ctacagatgg ttcagcttcc accaggattt
    47401 catttttttg agtatcggat tctgccgtct ccactggagc agtttgtgct gctgacggct
    47461 ggagagcatc agtagagctc tggtctgttt cttcatgttc aaacacgccc tttgtcgtca
    47521 ggtattcact gatatatttg ttcagtgcaa cgggatcttt gtgaatatcg atcggacgtt
    47581 cgcgaacaag gccaaaaata gtctgacggt catagccaag tgcttcgggc tgtttgcgca
    47641 ttgatgctga gatacgcttc cagtcttcgc gatccttgtc gataacctca tttgtcgccc
    47701 agcgatggat ggtaccgtca atgtttcctg catccacatc accgggccag agggcgcagg
    47761 ccagttcatt gtcgagtgtt ttccatgtct gtttgtattc gcggcgaatg gcaacagtga
    47821 cagccccggt tttttcagca gcgttttcag tgttctgttg gttgactctg gcgcgggtga
    47881 gatcaacaac agacgtgtat tttccggttt ccttgcgttc accttcgcga cgttttttcc
    47941 agatgcgcat ctctgcctga atttcaggcc atttagcgcc aggctcacat ttatgcttaa
    48001 cccacccgat ggcatgcagt ttaagttcag gatacatggc gttaacttct ggcattttca
    48061 tcaacgcttc aacgatatgt ccgccgaatg ttgccatgtc ttcctgtagt aattcctgtg
    48121 cgctaatcac catatcaacg gtgatgtttt cgcatgtgtc gaatttaacc aggactgcgt
    48181 tctgtacttc aggggacagc ttgtcaaaat tgacgttcat cggatcggat tctggttcga
    48241 ccggtacaaa ggaagctgac tcctcatccc agcggttttc ctgcatatat tcggtatccc
    48301 aggaatcgag ggcagggcgg ggtatgccgg gtttatcctc gcagacaata aatttataag
    48361 cgcagtcctg agctgccggg aattgctcca gaaattgcca gtgaaatttt gcgcgtgcgc
    48421 gacgctcatc accggcttca atggcagtgg ccaccgcaac agcgctatct tcttttatgg
    48481 cctgttcgtc aggaatagca gcgcaaataa agattttact cattgtgttt taacctcatt
    48541 acagatttaa gggtgaacaa atccctgcca ttgctggcat ataaaaatga aaccggatat
    48601 taattacggt gctgttttaa agtcctgccg gtatttcgtt attattagtg tgagtagttt
    48661 tatctaccgg ataacagtta ccgggaattt tttgttctgc tgctgcagcc atgcattctt
    48721 tcattgaacc gtataagcca gtcaccagct caagagattc gccggaaaca agataaactg
    48781 tcagaacgag tgcaaatgtt gtattcattg tttatatcct ttttgcagca ggtccagacg
    48841 agccagcatt gaaggaatgc atacttcatt taacaggtcc tgctcgagtt ttctctgctt
    48901 aatggcgtct tcaataaatg ttttgtctcc agtgataacg ccaatttcga aacgaagttc
    48961 agacgtgctg gcattacatg ataacttttc cattatcgcg tcctcaacaa tgaattttgt
    49021 gatgcggtgc ctggtgcctc caggtgacgt taaccagtta acaattaacg ccggatacag
    49081 agcattctcg ttactcagca aatgaccgct ttaccgattt aactgttccg cgtgcgctga
    49141 gccgcattca ccgcatcaca aaattcactt ttaaaaaagg gcggcagagc agtcacggag
    49201 taaaactgat accgccaaat gtcaccagaa tattgataac agagggcgtt gcagcggggt
    49261 tgtcacttaa gcgtatggtc aacctgacaa cccggtgtcc tcaacgggga aagaataacc
    49321 ccgccatact taccgccgcg ccatttcgcg gattgccaca accggaagcg cacggtcgaa
    49381 ttaaatttaa cgacggctct aagggagaag gacttcgccg tgcactttcg tgttatgccc
    49441 tgacttttca gggatatatc cttttagtaa actgtcagtg ccggattctt atctgtgtcc
    49501 ggcgcacgac cacacgtagc agcgtgttgg tctccatttt taattcagcc cttaatggag
    49561 gataaaatgc caaacaaacc atgccctgcc tgtaacgctc tttctggctt tttagagaag
    49621 ggcggttatt acatttttaa ctgtccagaa catgttgaat ttcatatatc aaaacttgac
    49681 agtatcatta caaagccaaa tcagtatcag tctgatttac tgaataaaga gttaaacgcc
    49741 gcccgagatt aagggcgtag tggcccatta aaaatattgc aaagaccaac tattgttgaa
    49801 ctggattaaa ccagtaattc tctattgctc ttattgttac catcggatga ttgccggggg
    49861 ttattttaag ttcgggagga aaaggctctc catcagcagc catcattgag tatgtgaaat
    49921 ccgccgacgc agtccctttc atgataattc cgaatttttc aagtaatgag agcagttccg
    49981 gtaatcctgt gtcatctgaa taactttcct catagaaaga agcgattgcc gcaggagatg
    50041 acagttctcg ctctgcaatt tttttgtagt tttccagaat tctttttttg aatacttttc
    50101 ctcgacatga aaacccatca ccgaggcaat ccgctttgca gtttcttcag tattctggtt
    50161 gtttgttacc gaaacagagt acaatccggt aaacgcatcg cgcacattac gagccatatt
    50221 atcaatgtat ttcttcgttg cagattctaa ttcaacttcg ttcagacgtt ggtgaagtgc
    50281 atgttctgca atttcctgga tttcttttag taaatcttta aattccatct ttaactccgt
    50341 tagtcgttag attttgccga actggaaagc gcctgtttaa actcactgaa gctgagagct
    50401 tcctcgcctt cggcaaggcc ttcgaagtat tcttcgtaag ccttttccat gattgtgtcg
    50461 aaatccatat cactcacctg agtttctttc cagccagcga cgggcaccat tttcggtttt
    50521 aaacgttttg cttttggtat acgtcatcgc ggtgaatgta ccgtcctggt tgggaaacac
    50581 gccgtacacc agagattcgt tgttgccaag atcgatagta tccatgttga cctcatttcc
    50641 ccttaacgcc gggtagcgga acaaaaacct gctgcatagt tattaaagtt gaaccctgcc
    50701 gtcatgttca tacgcctcgg gctggctact taccccctga ccactgcttg gtaactcgaa
    50761 gtattgcccg gcgttctgtg gggcggggtg ggtggttggt gtatgtaatc tacaattaaa
    50821 aactgttttg tgtcaacagt ttttaattgt tgttttgggc aaaaaaatcc ctcgaaagag
    50881 ggagtatgaa aattgttcaa ctcagataga gaagggaaat tgtcgccgag aatgtgtcac
    50941 gcttacaatc tcaatgcttg aagcagctac tctgtacagg attatgtagt tagggtgggt
    51001 cacgatctct ctcaatccag aaacccgttc gcttggtgga tataagtacg gatgctcaga
    51061 tagaggtaat accgatgttt caatgcgtat ttttagtcta cgtgctgccg gtgggttctc
    51121 cttggcgatg taagttatga tctggcgcaa atcatcgcga gcagacggta gccataaaat
    51181 gggtaacatt actcgctctt gttagttaca gcaatttgag caataagatt ttccatttca
    51241 gccattacct cgtcatgtgg aattgcgggg cgagtgtctg caaggcttga cgttacttta
    51301 gtgcgcaacc attcgttgta actgttttct tgttcggtag tttcgaattc tgaaactatc
    51361 ggagaaaggg ctgtacccat ggcataactc ctcttcttgt actgtggtca cgcccggcgg
    51421 cttttttgtg ccgccagcca cctagcaatg gtttcttcca ttgatttttt cttgtctttg
    51481 atttcttgaa gcattttttc ttggtcttcc tcaggaaacg cactaaaagc ttggagcagt
    51541 tcgcgttggc gaggaccaat tttcatcgtg tcaggggtga aaatttgctc acactcttca
    51601 ggaggcaata aaaaccaatg caatggatgc cctgaaacct caaccagttt atccaaactt
    51661 gaggctttag gtgtagcctt accgctgacc cattgttgaa cagtttgttg tgtcacacca
    51721 attctacggg caagctcagc ctggctccat ccagtttcct gaagaagctt gctgattctg
    51781 tacatagata cttctagggc gctcatcatt attcaatttt acaggtaaat actgttaaaa
    51841 gcatcacaat aaaaaactgt tgattgcata cagtttttta ttgtaggctt tgcttatagt
    51901 ttttagagga gggcaaaatg ctagatagca ctcgcgaaaa aattaggcag aaatacactc
    51961 aggctgaaat aggtcgttat atgggggtcg ctcaacagac tgtttggcaa tggtttagct
    52021 ttggcgttcc cccaaagcag gtaattccgt tatgccaact aatgaagtgg gaagttaccc
    52081 cgcatgaaat ccgcccagat atttatccta acccaaccga cggtttacct gttggatgta
    52141 aggttaacac atcaaatgcg ccggagttga ttcatgaaaa tcaagcatga acacatccgc
    52201 atggcgatga atgcctgggc gcatccggac ggcgaaaaag taccggctgc gaaaattacc
    52261 aaagcgtatt tcgagctggg aatgacgttc ccggaactgt atgacgacag ccatccggaa
    52321 gccatggctc gcaatactca gaaaattttc cgctgggtgg agaaagacac tcctgatgcg
    52381 gttaaaaaaa ttcaggcgtt gttaccagcg atcgaaaaag cgatgccgcc tccgctggtg
    52441 gcccgaatgc gcagccacag ttccgcttat tttcgggagt tggtagagac gaaggaacgg
    52501 ctggtgaaag atattgatga tttcgttgca tcagcgatcg ttctgttcga tcagatgaat
    52561 cgtggtggcc cggcaggaaa cactctggct gtgcattaat tgggtaataa atatgagtaa
    52621 tgacaaaaaa ttgacactga gcgtttacga aaacagtccg cacatctggc gtggcggttt
    52681 atctgatgtg gagctggcag agtggttgat acataaagct aatgcgctgc tctggcgttt
    52741 gtcagccaga gaacagcgca aggaaaccag aataaagctg gctgatgcag aagcgtgtgc
    52801 cgggcttatt gaggattata caaatcttgg tatttcttca gcagagagtg atcccattca
    52861 gcctctgagc agggagtcaa tccagcacgc tggttgtatg gcacatcttg taactgctcg
    52921 tcaacatgag gtgggtattg gatcacttcc ggtgggatat tcgctgattc cagagctggt
    52981 tgaagcaaga aaatcagttc agaaaaagag agatgacgca cttcaattat tgagagagca
    53041 ctatggcgcg ataccagaat gcgaacagca tcgataccct gaaggttatg aatggatgca
    53101 gtctcttttt gaagttcgct aatcaatatg tcgagacgaa ggtatgtttc ggcgcgcagc
    53161 caggctctgt aatccgggag catttcgggg ctgttacacc agcggtttgt tgctgcaaca
    53221 tttaatacat gagcctgata aaggcttttc aaaaaataca tgtcgaacct cctctggttc
    53281 tgtcgattgg gaaccacaga ttatatccgg aggaaggttc ggcaccagat gaggtagcca
    53341 tgcgtgatta cgcaaaagtt tctccgcgat tctggctggg agaaacgggg agagaactta
    53401 gaaaggcggg tgcagaagcg caagttgttg ctttttacct gatgacatcc cctcacgcaa
    53461 atatgctggg tttgtattac ctgccagttt tataccttgc tcatgaaacc gggcttggtc
    53521 tggaaggggc ttcaaagggg cttaaaaggg ctgttgaagc tggtttttgt agctatgacc
    53581 atgatgcaga gatggtctgg gtccatgaaa tggcagcctg gcaggttggg gaaacgttga
    53641 agcctggcga taaccgttgt gcaggtgtca ggaatgagta tgcatcatta cctgaaaacg
    53701 cttttctgtc agtgttttac gacagatata aaacggattt ccatctggat gtgaggcgga
    53761 ataatagccg aaattcggta aggggcttcg aaggggcttt taaggggctt cgaagccaag
    53821 aacaggaaca ggagcaggag aaagaacagg aacaggacaa aaacactatg gttcatggca
    53881 aaaaaaacac cacgaaccag gcaggggatg ttcagaccgt caatcctggt cagccagcag
    53941 gcacgacacc ggaagccgat tcagcgtatg cgctgaaagc cgattcgggc gctgtgcagc
    54001 aggtgatgac cgcagggtcg gagcaatcac accaactgca gcagcctgaa gccgattccg
    54061 ccattcagcg ggaagccgat cgggtagtcc cggaaagcac cgggcagtct gtgggacgag
    54121 tggattatcc ggatgtgttc gaacaggtct ggcgggaata cccgttgcgt gctggggcaa
    54181 acccgaagaa atccgctttc agtgcctgga aggccagatt gcgcgagggg gtgccaccag
    54241 agaccatgct ggatggtgtg aggcgttacg cgagatacct ggcggcgacc gggaaagcgg
    54301 gaacggaatt tgttcagcga gcgacgacgt tttttgggcc ggaccggaat tttgaaaacc
    54361 cctggttgct cccggtaagc ggcacgaaca accagcgttg tgtgaatcat atttctgaac
    54421 cggataccga aattccgccg ggattcaggg ggtgatgtgg catgaaaaac attgcggcag
    54481 ccggggttct tgaacgtatt cgcagacttg caccacaggc gtcggttcca ccgtaccgga
    54541 cggtggagga gtggcgggaa tggcaacttg
//
LOCUS       DAZUDJ010000029        53366 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.029, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000029 DAZUDJ010000000
VERSION     DAZUDJ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 53366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53366
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.029"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..336)
                     /locus_tag="ACHY1N_002323"
     CDS             complement(<1..336)
                     /locus_tag="ACHY1N_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4044624.1"
                     /translation="MAKNDFKAFATDRNANVISQEEWEALPALLSGFTAGKASSAQVN
                     KVIRQASFIAAALAQFVSDKTQRDVLDNGDLPGFVELLGSGFAVEYLSRKNPFGDIKS
                     DGTVPTALEN"
     gene            complement(336..1016)
                     /locus_tag="ACHY1N_002324"
     CDS             complement(336..1016)
                     /locus_tag="ACHY1N_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2612 domain-containing protein"
                     /protein_id="HFS4044625.1"
                     /translation="MSKYTELITNYHATKPKFLAHVDLMTRPLIDVAAATRGLITAFD
                     IDSAVGVQLDILGLWIGRSRVVSQPISGVYFSWDTDGLGYDQGVWQGPYDPDSGYMYL
                     SDETYRVILKAKIAINNWDGRNDSLPAILDAATAGSGLRMQIVDNQDMTISVWVFPDT
                     DISDVSRELIAAIKQGYLTVKAAGVWAGGIETPSVETPSEGSKFFGFDMDNEFISGFD
                     VGAWGVLL"
     gene            complement(1013..2212)
                     /locus_tag="ACHY1N_002325"
     CDS             complement(1013..2212)
                     /locus_tag="ACHY1N_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001197067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFS4044626.1"
                     /translation="MALNLDSLGLSAKVTAEGISAPDYQTILSTLISYFQQIYGSDAY
                     LEPDSKDGQMVALMALAIHDANNMAITVYNCFSPATGYGAALTSNVKINGISRKGATN
                     STVDLLLAGTAGTTIINGSVKDSNNVIWRLPASVVVGVDGTVMATATCSVSGAVAALA
                     GTITEINTPTRGWVSVTNPAAATVGTPAETDAELRIRQSQSVALPSITPFEALDGAVS
                     NVTGVTRHKLYENDTGSEDGNGLPPHSVAVIVDGGDVTDIAQAIRGNKGQGTATHGTT
                     SVTVPDKYGNPHVIKFSRSSDVPVYARIKLKVFTGYTSQIGQQIQQAISDYINSLTIG
                     DSVLLSRIYSPANLGVVSGGNARYYDIQELTIGKSPGALSSSNIDIRYNESASCTPEN
                     IVITVES"
     gene            complement(2212..2565)
                     /locus_tag="ACHY1N_002326"
     CDS             complement(2212..2565)
                     /locus_tag="ACHY1N_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044627.1"
                     /translation="MRYRREDADGDYTFGSGDDTWLINSPEAVAQAVKTRFELWYGQW
                     FLDTTEGTPWIQSVLGKQKPETYNLAIRKRILETRGVKSILSFNTTVDTTTRRVMFSA
                     EIDTLYGITTVTSEA"
     gene            complement(2565..3317)
                     /locus_tag="ACHY1N_002327"
     CDS             complement(2565..3317)
                     /locus_tag="ACHY1N_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gp138 family membrane-puncturing spike protein"
                     /protein_id="HFS4044628.1"
                     /translation="MPVSLSAQLGSKEQADVRLAGSVMSALRVSMPGIVQSFDPDTVT
                     VVVQPAIKGYEPDSNGINQSTTLPLLVDVPVVFPRGGGCTLTFPVKAGDECLVVFADR
                     CIDFWWQSGGIQEPVDDRMHDLSDAFCIVGPQSQARKISGINTSATQLRSDDGSTYFE
                     LNPDTRKIKIVAPGGLDVVAPLADFSEKVTIHGLLTWMGGMVGSVVSGVASKITGAVE
                     FLGSVKANGKPIDDTHTHGGVQRGGSNTDGVN"
     gene            complement(3377..3616)
                     /locus_tag="ACHY1N_002328"
     CDS             complement(3377..3616)
                     /locus_tag="ACHY1N_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4282 domain-containing protein"
                     /protein_id="HFS4044629.1"
                     /translation="MFGFDKLITPKIINVLYGITMLLLVVAAIITFVNGKAAGALVLL
                     LCAVFCRIFFECIMVSFKNNEYLRRIAEALEANKQ"
     gene            complement(3756..4091)
                     /locus_tag="ACHY1N_002329"
     CDS             complement(3756..4091)
                     /locus_tag="ACHY1N_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013578265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044630.1"
                     /translation="MKKVFFCLFLALPLTVSAATQCGPFRFDAGNDGLMHINGQKPET
                     QKMTFLKQKDDFDNVMMQWMLPDPNTGRWLGMDYIKRNKKAILNVEVIRKNMDEPREF
                     WTYDCRKVK"
     gene            complement(4088..5122)
                     /locus_tag="ACHY1N_002330"
     CDS             complement(4088..5122)
                     /locus_tag="ACHY1N_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044631.1"
                     /translation="MSKNWMRHFELLLVDDKGDGIKISELKVTFNIQKMPATIFNGFV
                     GNFKVYNLSPTTQNRIMQKEFSRIQVIAGYKGQPDAAGNYPDENVGMIFNGDIRFTVT
                     GKDNATDSWIMLQCIDSWEGHLNASVKTTVAAGWKYRDLFSLGMKSFEPYGIESGAVP
                     DMPETVFPRGRVVYQNTSRLMNHIAGQCKANWWYENNLVNIVPEDKYIGVATVLNANT
                     GLIGMPQQTMGAGVNVRCLINPNIKLGGLIRLDQASVYRASLSNDQVAKSPARLDESE
                     SDGNLYVNGLAGMSQPASINTDGDYIVGSIDYTGDTRGQAWYMDLLCLAKGGKELLAK
                     GTLDKVGDVE"
     gene            complement(5125..5427)
                     /locus_tag="ACHY1N_002331"
     CDS             complement(5125..5427)
                     /locus_tag="ACHY1N_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044632.1"
                     /translation="MKAVEIPLVADNQTFATTINGSVYHLSVIWRGEYWVLDLADSNG
                     SAIISGIPMITGADLLAQYRYMDLGFSLVVLCDVAGQENPTQFDLGTLSHLYVFTE"
     gene            complement(5431..6081)
                     /locus_tag="ACHY1N_002332"
     CDS             complement(5431..6081)
                     /locus_tag="ACHY1N_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HFS4044633.1"
                     /translation="MDFLSVLLQQRTRSIGIIIPDVVITEKHTDALEITEHPVEQPTN
                     AGASGEDAGYISEHAFRRPSEVVMETGFSGGGSLLDFASNLTATSLLGLSPKELYQEL
                     LNLQRNRIPFDVTTGKRIYNNMLIKTLEVTTDKSSENVLLATLTLREVIITSTQSVRV
                     APKNNMTEGVGTSAVQNTGTKTTVPPNNSILKSLPQMAQEGISTVDGYLSNLFLGR"
     gene            complement(6081..8087)
                     /locus_tag="ACHY1N_002333"
     CDS             complement(6081..8087)
                     /locus_tag="ACHY1N_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase catalytic"
                     /protein_id="HFS4044634.1"
                     /translation="MNAETIKDFLVSLGFSVDDAGAKKFGSVLAGTTANVIKMGLAVE
                     GAALSVVAFTAKIASSMDNLYWASQRTGATVQGIQSIGYAVSQVGGSVDAARSSLESL
                     SRFIRNNPGAEGFLNRLGVQTRDASGNMRDMAAIFTGVGQKLSSMPYYRANQYAQMLG
                     IDENTLMAMRRGVGQFSAQYSKMVKAIGFNADQAALSSNRFMTSLKSLGEMAGMARDK
                     IGSNLADGLAGQIDNLRKKIIENFPKIEVTITKVIKGILWLGEIVGRVAFRIVDGVGD
                     IIEWWGKLDAETKTLIEVIGGLVVAMRILNSTFWMSPIGLITGLIVALGLLWEDYKTW
                     KEGGNSLIDWEKWQPAIDKAKDAITWLRDHLLELKDGVGGWQNALEILGTFIAGVWVS
                     KVLGAFGKISGLPVPPWLKLWALYAGYIVSDRENIADSAKSSLRYTKRIIGDTLAAIG
                     IKTDIGRRDVSEVREWPAWMDWLHGGPGKVIRQGQSNGVVHGSNVQPDIPGGGTLADR
                     NNNPGNIRPVSGKGFRFFESALEGWEAMKNQLMRYFTGKTTGRALQTIQDIVSTWAPA
                     GDNNDPKKYAQDVAKWMGVSPNAILNLTDPQTMGALMQSMARKEGYSNWNSPLAYQAA
                     AGSLNQQTVINVHGVNNPQEAANLIADKQGAVNARAVQQLKGPA"
     gene            complement(8077..8253)
                     /locus_tag="ACHY1N_002334"
     CDS             complement(8077..8253)
                     /locus_tag="ACHY1N_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP pyrophosphohydrolase"
                     /protein_id="HFS4044635.1"
                     /translation="MPDGLSYLLNPVDAGLIPYTALKDGSVDLYDIALLNDHLAVKAD
                     NQRRIEKWREDNER"
     gene            complement(8265..8717)
                     /locus_tag="ACHY1N_002335"
     CDS             complement(8265..8717)
                     /locus_tag="ACHY1N_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001703548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0098003 - viral tail assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HFS4044636.1"
                     /translation="MEFEIKGVKYRVAKLSVFDQLKVTRKLLPVLAGMMSDFGSIRSR
                     LPADGKIDTVKFEQLKPVFETMLPRIAEELSSLTEDDTDAIIHPCLAVVSRRHMDGWV
                     PVFTQGELMFDDIDLLVMLQLVARVVADSLGNFLPTPLTSTTQSLQQG"
     gene            complement(8721..9161)
                     /locus_tag="ACHY1N_002336"
     CDS             complement(8721..9161)
                     /locus_tag="ACHY1N_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3277 family protein"
                     /protein_id="HFS4044637.1"
                     /translation="MSTYSFMDVTATLTGPTGSIDLGYGSASSEEGIVVAMGGPKNTM
                     TIGADGEVMHSLHADKSGTITVNLLKTSPTNKKLSLAYNAQSQSSATWGNNVIVIRNK
                     VSGDIITARSVAFQKQPDNANAKTGNTMPWVFDCGKIDQVLGEF"
     gene            complement(9172..10317)
                     /locus_tag="ACHY1N_002337"
     CDS             complement(9172..10317)
                     /locus_tag="ACHY1N_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3383 family protein"
                     /protein_id="HFS4044638.1"
                     /translation="MAQGLPVSNVVNVDVIMSPRAASGRNFGALLILGPSTIIPVSER
                     IRRYSAAEDIGKDFGVESPEYKAAQVFFSQSPKPQEVFVGRWVKTKGDSEQATPETLE
                     QAVNAMLDYTSWYGLGIADDADIPDADWLKVAAAIESSSVSRILAITTSDEKCLQTAS
                     RDDLASKLKTAGYSRSFIQYSSGNKYAALSAFGRAFTVNFNGSNTAITLKFKQEPGVG
                     YETLTVSQASALDAKNCNVFVYYQNDTAILQQGVMANGDFFDERHGLDWLQNYVQTNL
                     YNLLYTSTTKVPQTEAGITRLLSNVEKSLDQAVQNGLIAPGVWNGGDLGQLSSGDTLP
                     KGYYVYAQPLDEQAQSEREARKAPVIQAAIKLAGAVHYADVQINVVR"
     gene            complement(10321..10884)
                     /locus_tag="ACHY1N_002338"
     CDS             complement(10321..10884)
                     /locus_tag="ACHY1N_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044639.1"
                     /translation="MGELRLSNNTSTERGWLIPTSGDPDYDEALDRLLSQWMRNVSGL
                     SAGMVRPRWQKEQPPLLPVETNWCAFGVIGWSGDDSPAFTRQTDDGSQLWRHETIECM
                     ASFYGPAGMVYASRFRDGISVPQNNAALNALGLSLGDYTGLTPFPELINQQWVRRYDM
                     TVRLRRKVVREYGIKSLVEAPVIFFGD"
     gene            complement(10859..11248)
                     /locus_tag="ACHY1N_002339"
     CDS             complement(10859..11248)
                     /locus_tag="ACHY1N_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001687820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor"
                     /protein_id="HFS4044640.1"
                     /translation="MPTLDVTDVLFDPDFCDFNLWVTRRVQTVDEDGIGSDSEVKKQF
                     AGVVTVDRSLENRRMQAGQVISGAILIVTTERLTQGQTGRDADIVTYQGRDYRVTFVD
                     PYTAYGAGFVQAHCELMPFDGGTPVEQ"
     gene            complement(11235..11789)
                     /locus_tag="ACHY1N_002340"
     CDS             complement(11235..11789)
                     /locus_tag="ACHY1N_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044641.1"
                     /translation="MSFKSGVTTRVDNAKAILDALRSLTKKDVLVGIPSEDSGRDDVP
                     FGNAGIGYLNEYGSPEQNIPPRPHLVPGVKSAEEQTVPQLKAAAQAALDGNAAGAERA
                     LNRAGTLAANGVRRYMTITGFTPLADSTVEARARRGRKGATLELARRAAGESPGTDLA
                     KPLIDTGQYRRAITHVVRDKDADS"
     gene            complement(11786..12193)
                     /locus_tag="ACHY1N_002341"
     CDS             complement(11786..12193)
                     /locus_tag="ACHY1N_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4054 domain-containing protein"
                     /protein_id="HFS4044642.1"
                     /translation="MPKNQSLPAVSDFRRDFPQFADPAKYPDAQIGFRLNLADELLSE
                     NVTGKKLFPYFAGLFVAHYMTLWAADSRAMLAGGPGGSTNGVQSSKSVDKVSVSYDTS
                     ATLNPDAGFWNNTRYGAEFYQLITMFGAGGRQL"
     gene            12192..12413
                     /locus_tag="ACHY1N_002342"
                     /pseudo
     CDS             12192..12413
                     /locus_tag="ACHY1N_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706593.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12423..13364)
                     /locus_tag="ACHY1N_002343"
     CDS             complement(12423..13364)
                     /locus_tag="ACHY1N_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2184 domain-containing protein"
                     /protein_id="HFS4044643.1"
                     /translation="MITFDQATVDSSGAFLIGELERLDQTLNLPLVGYTWTRDIQLRE
                     DVSIADDISSWTNTSFAAAGTGANPNGKNWVGKDSTAIAGVNVDIGKSGNPLNLWGME
                     LGWTVIELQAAQQVGRPIDTQKYDGMQLKWQMDNDEQVYVGDSALNLKGLVTLDGVPV
                     NNAAKTWATSTPDEIRASINQVLSDAWAASGYSVVPRDLLIPPEQFALLSSIIVSSAG
                     NQSLLTYLQTNTISYHQNGVPLNIRAVKWLKGRGVGKKDRMVAYTNDKKYVRYPLVPL
                     QSVPVQYRGLYQIVTYYGKLGAVEPVYKETISYVDGI"
     gene            complement(13376..13882)
                     /locus_tag="ACHY1N_002344"
     CDS             complement(13376..13882)
                     /locus_tag="ACHY1N_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044644.1"
                     /translation="MNNVFLYRMPVGIAGAVSRPQDLTVEPVVLKSDNAFAAYGLAGK
                     YDDDGFFVPLADGDTADKVKGIYVRPYPTTSQPDMVRQVGTGKNFPGDAMKRGYVTVN
                     LGSDFDASTIKKGDPVYVVVSTDESIKVPLGGFMSTSVSGKNVVLTNAEFTGAGDADG
                     NAEISWKI"
     gene            complement(13886..15106)
                     /locus_tag="ACHY1N_002345"
     CDS             complement(13886..15106)
                     /locus_tag="ACHY1N_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2213 domain-containing protein"
                     /protein_id="HFS4044645.1"
                     /translation="MKYFFNTRLGETRYQLADGSLLCKDVPIGRTGKQLYGADDLPKL
                     KPDKFGEIVVTRSPEQVFHPATLASFEGMSITVLHPEDENGDVRLVNPENWKELAVGH
                     LQNVRRGTGVQSDLMLADLIVKDENAIQLIEDGLREVSCGYDAEYKQTEPGKAEQVDI
                     TGNHVALVPKGRAGNRCAIGDRDTMANQKKSWWTRMRTAIKTGDADTMNELVESAPAS
                     VTGDEGDLPQGVNLNINLSPQQPLPDKAPEMGGGPTGDSDDDLKTLLKALLAKLEGNA
                     TGDNDNKPDDNPTGDGEDDEEETTITGDSAWRAEVIVPGIDLSRKMKPTAFKREVLAS
                     ADKTLVRQIVGDADIRKLPKQSVDMAFNAVSEIAKGRNTRATTGDAQRPNMGMTSIAS
                     LNKQNAEFWANRKG"
     gene            complement(15121..15855)
                     /locus_tag="ACHY1N_002346"
     CDS             complement(15121..15855)
                     /locus_tag="ACHY1N_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor head protein"
                     /protein_id="HFS4044646.1"
                     /translation="MTNRRNRQAEIRYRTSLRRIARAVGDIVNGRYDGSNDSITEIIE
                     ALERYSEIITPWATKVAENFTADLTRQNEKVWRQHSKNISRELRNLVESAPVGQVMQS
                     IIAEQVKYIKSLPLEAADRVYDIQNRAIEAVVTGGRAEHFAKEIAASGDIAKSRADLI
                     ARTELGRATGALDQARALAIGSNGYIWRTAEDGDVRHSHREMEGKFVEWGKPPTLDGM
                     TGHAGEFPNCRCYKEIVFPTSHSYPA"
     gene            complement(15746..17212)
                     /locus_tag="ACHY1N_002347"
     CDS             complement(15746..17212)
                     /locus_tag="ACHY1N_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1073 domain-containing protein"
                     /protein_id="HFS4044647.1"
                     /translation="MARNKQALRRTAQATADGYENFIARVGMQTPNQHSASTYRANFT
                     SRNRMLVEWSYRSSWIIGEAVDAIPDDMTRKGIRITSEIDAKDRGILESQLDELQIWD
                     ALNDVLKWSRLYGGAVGFIMIEGQAPMTPLRPETIGKGKFKGILPLDRWMIDPVLTRR
                     IKDMGTDLGKPEFYDVVTTATGIPAWRIHHSRLIRFDGVTLPFQQKMTENEWGMSVVE
                     RIWDRLTAFDSATVGAAQLVYKAHLRTYSVEKLRELIALGGPAYEALLKNIDLIRQFQ
                     SNEGMTLMDSRDKFETHQYSFSGLDDILSQFAEQISGAVGIPLVRLFGQSPKGFSTGD
                     ADLANYYDRVSSLQERRLRLPVRRILDIMHRSELGKPLPDDFTFEFNPLWQMSDVDRS
                     TVALNTTNAISTALGDGLMTLKAAMTDLRENSDVTGIGASITDEDIENAEDEAPPGIG
                     EPDDEPQEPSGGNPLSNQPTQDSAGGRRHRKWSLRWFK"
     gene            complement(17212..18834)
                     /locus_tag="ACHY1N_002348"
     CDS             complement(17212..18834)
                     /locus_tag="ACHY1N_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerL protein"
                     /protein_id="HFS4044648.1"
                     /translation="MPLPFPFDFKHPDYQMVFEWRMERLQRIRQNPEILPVLKQFYRT
                     NPAQFIIDWGMTTDPRNIDYGLPVTIPFLLFPKQEEWIHWIMERWGNRENGITEKSRE
                     MGLSWTAIGLACSLCLFNKEMVIGFGSRKEEYVDSTGDPKALFWKARKFVETLPVEFR
                     GSWSEKKHAPYMRVEFPETGAVIKGEAGDNIGRGDRTTLYLVDEAAFLQRPLLIDAAL
                     SQTTRCRIDLSSVNGMANPFAQKRHGGKIPVFTFHWRDDPRKDEEWYRRECEKIDNPV
                     VVAQELDLNYSASAEGVLIPSEWVQAAVDAHIKLGIQPTGKRLGAMDVADEGRDKNAF
                     STRHGFLLENVREWSGVGSDIYQSVEKVFGFCEQDNLEEFRFDEDGLGAGVRGDARAI
                     NELRNAARRPSILATPFRGSGAVFDPDDEAVRGDNGQAARLNKDFFANAKAQSWWRLR
                     KLFQNTWRAVVEGMAYNPDEIISISSSMALKDKLIIELSQPTYSINGVGKIVIDKQPD
                     GTRSPNLADSVMINYAPMNSALNIWELLGRQA"
     gene            complement(18837..19409)
                     /locus_tag="ACHY1N_002349"
     CDS             complement(18837..19409)
                     /locus_tag="ACHY1N_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001703551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HFS4044649.1"
                     /translation="MTKKLKAKHEVFCREFLVDLNATQAAIRAGYVSRRAHVTGAELY
                     GKPEIRARINELKQERIDQLGIDANYVLMRLVEIDRLDVADILEDDLSIKPLSAWPES
                     WRRYLSGFNLAEMFEGRGDDREMVGILKKIKWPDKVKNLELLGRHVSVQAFKDNVKNE
                     VTGADGGPVRTEITNLTPEQAAEAYRKMMG"
     gene            complement(19471..19995)
                     /locus_tag="ACHY1N_002350"
     CDS             complement(19471..19995)
                     /locus_tag="ACHY1N_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044650.1"
                     /translation="MKLTYKIVIAAFFFSVFGALVWSANHYHSKYQAEKLRADKAEGE
                     VEYQGKVIANQALNFNRFNQIAENASRLNSLVDIGHEKTVIKYREVLLREKNCDFPVP
                     VDIAVGLLNYANRLRASALHADSGDIDSAGDRATTTRTLTYCQAVLWINPLLAAIEKA
                     NNQLAGVRQIEQSR"
     gene            complement(19979..20455)
                     /locus_tag="ACHY1N_002351"
     CDS             complement(19979..20455)
                     /locus_tag="ACHY1N_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003796 - lysozyme activity [Evidence
                     IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA];
                     GO_process: GO:0016998 - cell wall macromolecule catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="HFS4044651.1"
                     /translation="MQTLNSQRKAFLDMVAWSEGTDNGRQPTRNHGYDVIVGGELFTD
                     YSDHPRKLVTLNPKLKSTAAGRYQLLSRWWDAYRKQLGLKDFSPESQDAVALQQIKER
                     GALPMIDRGDIRQAIDRCSNIWASLPGAGYGQYEHKIGDLISRFKDAGGVVNEADL"
     gene            complement(20459..20800)
                     /locus_tag="ACHY1N_002352"
     CDS             complement(20459..20800)
                     /locus_tag="ACHY1N_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin, lambda family"
                     /protein_id="HFS4044652.1"
                     /translation="MKMHNAPHSWPDLLELLQSWWRGDTPLGAVVMSIVMAGLRIAYF
                     GGGGGWKRKTLEILLCGALTLTFASALEYVGWPKSLSVAIGGGVGLIGVDAIRGAAMR
                     VIGNKFGGSKE"
     gene            complement(21204..21638)
                     /locus_tag="ACHY1N_002353"
     CDS             complement(21204..21638)
                     /locus_tag="ACHY1N_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0060567 - negative regulation of
                     termination of DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator Q family protein"
                     /protein_id="HFS4044653.1"
                     /translation="MRNIQQVLERWGGWAADSNTTVSWAPIAAGFKGLVVSSSPGRLS
                     CCDDDGLIIDACVCRLQQVRKPEELDVIMLYYVYGLSKREIGRRRRCSEGFIRQQLQV
                     AEGFIEGCLCMLGVSLQMDPEVEIQRDEKSISALRKNCATLV"
     gene            complement(21927..24113)
                     /locus_tag="ACHY1N_002354"
     CDS             complement(21927..24113)
                     /locus_tag="ACHY1N_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFS4044654.1"
                     /translation="MSDSKPWGATPDEWFHFDLVLGRTAHLLPVVCNPSATISPDSKL
                     KALGKTPSRYNRDRQVTGIAQWTGHVVTEHDFARWSNEPDYGICVRTGHGWLALDCDS
                     EDEDIQADIRKTLVQLLGESPPRRWRANSNKCLYLLAVDGDFRKRIHRLAGDMGIIEL
                     LANGQQFVACGTHSSGARIEWDGGLPDEPPAITGEQLETLWQRLAEQLPVSVTTEAGN
                     TKMRDRSAFTPGATDDTAEYLDANGWTLLDGANGERYIRCPFEDGHSSGGDPTSTVYF
                     PAGTAGFEQGHFKCLHASCAHRDDGDFLNAIGIRNDDFEDLTSIEVAEPLPLPAFERD
                     KWGRIEATISNAAKAVVRSDFVDIDIRFDQFRDEIMFAPAGSGQWRAFTDADYARLRI
                     TMEKRGFKPVGRELIRDVVLLAADEQPFDSAITWLNGLEWDGVPRIECFYHTHFGTAD
                     TPYTRAVSMYMWTALAGRVLEPGIKADMVPILVGPQGCGKSSGVEALSPDPAFFTEIS
                     FAEKDDDLARKMRGRLVAEIGELRGLNTKELESIKAFVTRTHENWIPKYREFATQFPR
                     RLVFVGTTNEDEFLADKTGNRRWLPVEVSKVDVKAIKRDLLLLWAEAREVFQRLGGIQ
                     FREAEQLAASVHEQYTIKDAWLETIEKWLDTPDLMTNELPRNCEFLRASDVLRDAIGL
                     NPDRIGKREEMRISNVLQNCGYKRAQRRIGGKKCKVWEPLEPRGTT"
     gene            complement(24117..24317)
                     /locus_tag="ACHY1N_002355"
     CDS             complement(24117..24317)
                     /locus_tag="ACHY1N_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4044655.1"
                     /translation="MSGLTPQEMVKSLIDSGYTQNQIAEIAGVKQSSISRLLTGVHSD
                     PRFSTVRAIEKLFQEVTARQKV"
     gene            24459..25133
                     /locus_tag="ACHY1N_002356"
     CDS             24459..25133
                     /locus_tag="ACHY1N_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4044656.1"
                     /translation="MIDTTDILSQNIKYLMDKAKISSITELARRLQLNQPTLHRLVSG
                     EVKDPKYATLKQIADYFHVSPIDLAERSLQEMEKEDATGIKTYISLRFNKVPVLGNTQ
                     LGVGGLWSDTQYSVGSSDGFIYWPTKDEDAYALKCVGDSMMPRIKEGEFVIVEPNHDY
                     TPGDEVLVVTREGEVMVKTFLFERDGLFHLMSVNEDHPPVRVPRENIEKIHYVAGIAK
                     SALRMY"
     gene            complement(25509..26078)
                     /locus_tag="ACHY1N_002357"
     CDS             complement(25509..26078)
                     /locus_tag="ACHY1N_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044657.1"
                     /translation="MSEEKGILSRITESLSGVGGAIKSAVGAAREIQNLTVDYAVKEK
                     THILLDKLMDVQMQQMSLQELLIAAKEKIVELENEKVKQENWAAEAASYELYQPMRGT
                     LVYRSKLSADADQSPVYICPNCYEQKRKSILQAEGLVTKPGLGRAVNMVCSYCRASYL
                     FNRNALEARLPSEDENPGKAITDYDPYNQ"
     gene            26303..26452
                     /locus_tag="ACHY1N_002358"
     CDS             26303..26452
                     /locus_tag="ACHY1N_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044658.1"
                     /translation="MKPEHIHRLTGRDVLRYRRKNFDLMTGLAVATALGLIITFILLV
                     ARTTV"
     gene            26449..27351
                     /locus_tag="ACHY1N_002359"
     CDS             26449..27351
                     /locus_tag="ACHY1N_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044659.1"
                     /translation="MSLETSLELNNQLLAQHNALLERLIRTMASGIVMHPDTISRVQE
                     CRDTATEAENMSAAMTLDDLEFSDVIALAVFYPVATPITEDMLQRAVAYRDAEGDKRV
                     VQIDALDSALQGVKRARALLKPALLDLSRNILKFWDDLPTIGERRAFAEQLLDAPADG
                     RDEVKPKKASNKDGERTGPFYVKNVSGTAASELHTLRKLNEMLKKGHIEINRVEYLQL
                     QEEFARRDAANSSQNNDAKDDHTIDFAALRKQAEGLILQLAKGGYRAEAIAILEKQGA
                     RKLGEVTDENLAEVITLAEKALEG"
     gene            27354..28655
                     /locus_tag="ACHY1N_002360"
     CDS             27354..28655
                     /locus_tag="ACHY1N_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001386185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HFS4044660.1"
                     /translation="MPDVHAQLSPSSAHRWMRCPGSLALEATQPDKETTFAIEGTAAH
                     ALAEKVLRNRQSHPEHYAGCNVSMFLGSYPLRENPDDTSGPQVDDEMVEAVGRYVDTV
                     WTLAQNNELLVEQRVDFSHITGVEESFGTADSIIIAGSELQIHDLKYGKGVRIDAEQN
                     EQLQLYALGALEQFSMLYDFETVRLFIHQPRLNHVSEWALTVEELQAFGERAQEAATS
                     AILVLNIAECEGIETLPLENFIPGEKQCRFCKAKAICTAQKMQHLQTAASDFEDLTKP
                     VSEIITNASARVPLLTIEQLAEIYSQTDFIESWLKAVRDRVHNELNAGHPVPGFKLVT
                     GKQGNRAWSDEEAARALLKDQFRYKTEEVFDFKLISPTKAEKLIKKASPRRWSKVEAL
                     ITRADGKPTVVPESDPRPALNINPVNDFDDVSDDTLTADLI"
     gene            28671..29219
                     /locus_tag="ACHY1N_002361"
     CDS             28671..29219
                     /locus_tag="ACHY1N_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HFS4044661.1"
                     /translation="MKLKLNNVRLAFPSLFEAKTVNGEGDPRFSAVFLMSPKHPQLEE
                     IRKAMKQVAKEKWGEKWESIYNQLEKKLNLCLHDGDEKAEYEGFPGNFFLNAANKARP
                     AVLDRDRSPLIQADGRPYAGCYVNAVIDIWAQDNNFGKRINASLGGVQFLRDGDAFAG
                     GGVASADDFDDISEGADAEALI"
     gene            29271..29912
                     /locus_tag="ACHY1N_002362"
     CDS             29271..29912
                     /locus_tag="ACHY1N_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001520089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nmad5 family putative nucleotide modification
                     protein"
                     /protein_id="HFS4044662.1"
                     /translation="MSQPVLTNHLKTQIINNALEKAGIPKRKSALRAARVEWAERVRL
                     AAIGGVEKEAEILKNIKKIESMVTKIPDSLKTNSSLIRKDCCIYLNLAGARANIYFNG
                     NYRGYESGAPEHINKIAPAEFTLLGEDPLVTEFYSFDALYTQIKSDETEIIQNVSAAL
                     NKVRTVKRLLDVWPEAKELLPTDAPPVPLAPAVHRETLNEMIGLPTNTVSDTQ"
     gene            complement(29906..30595)
                     /locus_tag="ACHY1N_002363"
     CDS             complement(29906..30595)
                     /locus_tag="ACHY1N_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000215799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044663.1"
                     /translation="MTVGNKRQPNGLPEYYCHRGNDIKDAIVRDFIIQPVAHLKLITG
                     QTKTSYSGYPLTDQYYCFSFKKRSDENCTGAFFCGRDVAKDFIRRIGCTELPLFNPMK
                     SDTSAAIERSGSGSGSSGITVKPNADKKLFIDAARLLMTLWDSTSKGQTPLASVLNEA
                     ISGGIDKPPEIRHVVAVNTMLGNTKNTLTGLLDKARAKYPDVLFRDFDFTPLNEIVKR
                     SKSYNKHPPCY"
     gene            30657..32720
                     /locus_tag="ACHY1N_002364"
     CDS             30657..32720
                     /locus_tag="ACHY1N_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HFS4044664.1"
                     /translation="MSNILWGDLETYCDIPINNGTHAYAEGVEVMLFAWAINDGPVNV
                     WDITAGGGIPHGLYEAIADPETLLYFHNSHFDRTVLRYAMPRLAPPVERWRDTMVQAL
                     AHGLPGSLGELCEILGVPQDKAKDKEGKALIQLFCKPRPKNSKLRRATSKTHPEEWRR
                     FVDYAGLDIEAMREVYKRLPKWNYQGTELALWHRDQQINDRGVCMDMQLARAAIEAVD
                     QEQKRLAKRTQEMTDGEVQAATQRDALIKHIVESYGVELPDMQRSTLERRIADPDLPS
                     AVKELLAIRLQASTTSTSKYKALMKGVSHDGRLRGTLQFCGASRTGRWAGRLFQPQNL
                     PRPSLKQEQIDEGIEALKAGCADLLFDNIMELTSSALRGCIIAPTGKKLVVSDLSNIE
                     GRMLAWLAGEEWKLNAFREYDAGTGPDLYKLAYAKAFDIAPDDVDKHMRQIGKVMELG
                     LGYGGGVSAFITFALVYGLDLDELANAALPNIPRDVIREAKSWYDESVKRKSTFGLSE
                     RVFIACDSLKRLWRRAHPATCDFWYELERTVRTAIATPQKTLYCGYLKIRRDGAWLRI
                     QLPSGRAVCYPSPVIEQGNITYMGVNSYSRKWQRLKTYGGKLVENVTQAAARDVLAGN
                     MPLIEDAGYSIVLTVHDEVITESPDTEDFNDKALSALLSTNPEWAPDIPLNSGGFEAY
                     HYRKD"
     gene            32726..32941
                     /locus_tag="ACHY1N_002365"
     CDS             32726..32941
                     /locus_tag="ACHY1N_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001419980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANR family transcriptional regulator"
                     /protein_id="HFS4044665.1"
                     /translation="MSFKYRDNPLYYRAAREALRLEQSGEYDRAAKVWAKANRESHHE
                     LNQEWSERRSDFCLMQNMREKRKAVEE"
     gene            32938..33237
                     /locus_tag="ACHY1N_002366"
     CDS             32938..33237
                     /locus_tag="ACHY1N_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001385925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4406 domain-containing protein"
                     /protein_id="HFS4044666.1"
                     /translation="MIVYVAGPMSGYEQFNRPAFHSAAKRLTDKGYVVLNPATLPDGL
                     TQAQYMDICLAMLRCADTIYMLKEWEYSAGARAENALAEKLELNVLFEEWDSDGL"
     gene            33227..33520
                     /locus_tag="ACHY1N_002367"
     CDS             33227..33520
                     /locus_tag="ACHY1N_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HFS4044667.1"
                     /translation="MAYERESLIEKHLVAEVKKAGGVAFKFVSPGRRSVPDRIVLLPG
                     GRLVFVECKAPGKAPRADQLREHERLRELGFTVVVLDSKNLEGILCGEPITTK"
     gene            33493..34506
                     /locus_tag="ACHY1N_002368"
     CDS             33493..34506
                     /locus_tag="ACHY1N_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFS4044668.1"
                     /translation="MRGAYYNEIDPNAAQWLRNLIAAGHIAPGEVDERSIEDVAPDDL
                     RGFTQCHFFAGIGVWSYALRLAGRPDNKPVWTGSCPCQPFSSAGKSAGFDDERHLWPA
                     LFHLISERRPKLVFGEQVAGVNAWFDLVQTDVEAVDYAFGLVPFPAAGVGAPHIRDRA
                     YWVADASGERPQRWRKRLNSIEEDVWRSSTVRQHATQLPAGFCSPGGVVHPNLQHKPT
                     AGDKTRSRNLSGAIQISGMADSDDGRQQPSSWRGPSSQSYQTGNAPRRPNTINSCWDD
                     ADWLLCRDGRWRPVESCTFPLAHGITSRVGRLRAYGNAIVAPAAATFIRSFMECAGYD
                     LIC"
     gene            complement(34509..35438)
                     /locus_tag="ACHY1N_002369"
     CDS             complement(34509..35438)
                     /locus_tag="ACHY1N_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001689924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044669.1"
                     /translation="MSEFGSQQPAPQQILDLGVSTEGVFNEIEMGVLQNGISYLTQNG
                     LARICGVHRSNIADISREWEESFRHGVFARGRMEFISSYLQREQYNEPTLYIPINKDG
                     SVHYAYPEVVCMAILEFYAFVSQSAATPTALQFFRELSRAGMRGYIYTALGYIPDDPW
                     RHYHSRVSIMHGANSVPAGHFIVFNEIAGLMVDLIHAGLAVNQYTVPDISVGQHWARY
                     WSSSNYDATIGPRQRCQHYYPEEFNQSASNPQMVYAYPDNALAVFRHWLRAVYLPTKF
                     PKYLLSKAGLLAGGQTAALQIIDNFNNRALPNP"
     gene            35549..36943
                     /locus_tag="ACHY1N_002370"
     CDS             35549..36943
                     /locus_tag="ACHY1N_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140658 - ATP-dependent chromatin
                     remodeler activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2-related protein"
                     /protein_id="HFS4044670.1"
                     /translation="MPQNFIPRPYQDLIINHEIDIMRCNIWAGMGMGKTVATLTTLED
                     LFMAGAETRPALVLAPLRVAASTWPDEAVKWGHLRNIEVQPIVGNAKARSAALANSNA
                     SVFTINYDNLVWLVEELGERWPFGTVIPDESTRLKSFRLRGGGKRAAALGKVAHKYVR
                     RWINLTGTPAPNGLVDLWGQAWFVDQGQRLGRTYGAFTSRWFNSIQFPGQSWTKLEPF
                     AHSQGEIQRALADVTLSLDAADWFDIKDPIHNVIRVDMPPKARQQYREMEKEMFLELN
                     GEGIEAPNAAAKTLKCLQIASGAVYTDDTGSWSELHDTKLQALDSILTEAAGAPVLVA
                     YHWKHDLERLLKAFPRGRHLDQDPQTLRDWNSGKIPVLFAHPASAGHGLNMQDGGNIL
                     VFFSHWWDLEQYQQIIERIGPTRQIQAGHNRPVFIHHIIAADTMDEMVMERRNSKRTV
                     QDILLDAMKKRGIA"
     gene            36940..37140
                     /locus_tag="ACHY1N_002371"
     CDS             36940..37140
                     /locus_tag="ACHY1N_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4044671.1"
                     /translation="MSEKPDDLLTPDEVCQKLGITQKTLCEWNIKHRHRAILAPIRFS
                     AKVVRYERRNVDAFIQKCRSQY"
     gene            complement(37137..38534)
                     /locus_tag="ACHY1N_002372"
     CDS             complement(37137..38534)
                     /locus_tag="ACHY1N_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4044672.1"
                     /translation="MPRTVTHNPDSPNNDDVLAASEKWDACKPPYTSAHMKICVAAAK
                     IILAASGVARRSKYEKENYLRIDFSKAGKVTFYAEFPKKMGLKGKKLGEWPELAIQLA
                     REKALGMADCGLRAESVHAALEMYRDDLKAKVARQKLSPDSFTTYGVRINRIKATFGE
                     REVFSDVTYNRLVEVLDEWIATRSNNNALELFAELRRFWKFCAPTLCNGRNVAASLPD
                     DYVSSRVQKPTPTRLFTDIESIARLWLNVAACTSVHQKNAVRFMIITGVRPINVHNLR
                     WDYVHEEAGEIVYPEGVIGMRGAMKTQKAFRLPITPEIRRIIDEQKAWRDSVPECNRD
                     YVFLQPRDPMQPFSKRSLDKLVKTYSPDGAVKGIKHDGTVKGKDGAFNTMCRKFLKSN
                     VIALMKERGYSRSDRREISLLCLHHSSKSDDPMAEHYDFSDEILQEEIALKREAFEAH
                     ERSILAQVALLRRRG"
     gene            38749..39009
                     /gene="yfhL"
                     /locus_tag="ACHY1N_002373"
     CDS             38749..39009
                     /gene="yfhL"
                     /locus_tag="ACHY1N_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster ferredoxin YfhL"
                     /protein_id="HFS4044673.1"
                     /translation="MSLLITKRCINCDMCEPECPNEAISMGDHIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTIVKDPAHVETEEQLWDKFVLMHHADKI"
     gene            complement(39203..39283)
                     /gene="shoB"
                     /locus_tag="ACHY1N_002374"
     CDS             complement(39203..39283)
                     /gene="shoB"
                     /locus_tag="ACHY1N_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin ShoB"
                     /protein_id="HFS4044674.1"
                     /translation="MTDCRYLIKRVIKIIIAVLQLILLFL"
     gene            complement(39703..40083)
                     /gene="acpS"
                     /locus_tag="ACHY1N_002375"
     CDS             complement(39703..40083)
                     /gene="acpS"
                     /locus_tag="ACHY1N_002375"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFS4044675.1"
                     /translation="MAILGLGTDIVEIARIEAVIARSGERLARRVLSDNEWAIWKTHH
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKL
                     GVVNMHVTLADERHYACATVIIES"
     gene            complement(40083..40814)
                     /gene="pdxJ"
                     /locus_tag="ACHY1N_002376"
     CDS             complement(40083..40814)
                     /gene="pdxJ"
                     /locus_tag="ACHY1N_002376"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HFS4044676.1"
                     /translation="MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVT
                     TEGGLDVAGQRDKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYA
                     DAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAI
                     IGRAVMTGLKDAVAEMKRLMLEARG"
     gene            complement(40826..41554)
                     /gene="recO"
                     /locus_tag="ACHY1N_002377"
     CDS             complement(40826..41554)
                     /gene="recO"
                     /locus_tag="ACHY1N_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFS4044677.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     TLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLHCIQSLAGATGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDD
                     TMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTHYE"
     gene            complement(41566..42471)
                     /gene="era"
                     /locus_tag="ACHY1N_002378"
     CDS             complement(41566..42471)
                     /gene="era"
                     /locus_tag="ACHY1N_002378"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFS4044678.1"
                     /translation="MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGL
                     NVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            complement(42468..43148)
                     /gene="rnc"
                     /locus_tag="ACHY1N_002379"
     CDS             complement(42468..43148)
                     /gene="rnc"
                     /locus_tag="ACHY1N_002379"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFS4044679.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            complement(43421..44395)
                     /gene="lepB"
                     /locus_tag="ACHY1N_002380"
     CDS             complement(43421..44395)
                     /gene="lepB"
                     /locus_tag="ACHY1N_002380"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFS4044680.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGD
                     SLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSFIYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDP
                     VSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETK
                     ENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGVRLSRIGGIH"
     gene            complement(44411..46210)
                     /gene="lepA"
                     /locus_tag="ACHY1N_002381"
     CDS             complement(44411..46210)
                     /gene="lepA"
                     /locus_tag="ACHY1N_002381"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFS4044681.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLR
                     KGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTL
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPA
                     VNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            complement(46408..46887)
                     /gene="rseC"
                     /locus_tag="ACHY1N_002382"
     CDS             complement(46408..46887)
                     /gene="rseC"
                     /locus_tag="ACHY1N_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HFS4044682.1"
                     /translation="MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLVGLFLIASLFQLLFAS
                     DVAALCGAILGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSSEDASQ"
     gene            complement(46884..47840)
                     /gene="rseB"
                     /locus_tag="ACHY1N_002383"
     CDS             complement(46884..47840)
                     /gene="rseB"
                     /locus_tag="ACHY1N_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HFS4044683.1"
                     /translation="MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYE
                     LSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DIESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKA
                     KFSWTPTWLPQGFSEVSSSRRPLPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQM
                     LRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ"
     gene            complement(47840..48490)
                     /gene="rseA"
                     /locus_tag="ACHY1N_002384"
     CDS             complement(47840..48490)
                     /gene="rseA"
                     /locus_tag="ACHY1N_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HFS4044684.1"
                     /translation="MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMR
                     GDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
                     GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            complement(48523..49098)
                     /gene="rpoE"
                     /locus_tag="ACHY1N_002385"
     CDS             complement(48523..49098)
                     /gene="rpoE"
                     /locus_tag="ACHY1N_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HFS4044685.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            complement(49095..49250)
                     /gene="rseD"
                     /locus_tag="ACHY1N_002386"
     CDS             complement(49095..49250)
                     /gene="rseD"
                     /locus_tag="ACHY1N_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HFS4044686.1"
                     /translation="MIRLQHDKQKQMRYGTLQKRDTLTLCLLKLQLMEWRFDSAWKFG
                     LGRLYLG"
     gene            49506..51128
                     /gene="nadB"
                     /locus_tag="ACHY1N_002387"
     CDS             49506..51128
                     /gene="nadB"
                     /locus_tag="ACHY1N_002387"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HFS4044687.1"
                     /translation="MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEG
                     STFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGV
                     LFDTHVQPNGEESYHLTREGGHSHRRILHAADATGREVQSTLVSKAQNHPNIRVLERS
                     NAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTR
                     FMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLG
                     LGIDLTQEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAEDITRRMPDAHGVSTLPPWDESRVENPDERVVIQHNWHELRLFMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPELLTHSGPSILSPGNHYINR"
     gene            complement(51113..51850)
                     /gene="trmN"
                     /locus_tag="ACHY1N_002388"
     CDS             complement(51113..51850)
                     /gene="trmN"
                     /locus_tag="ACHY1N_002388"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HFS4044688.1"
                     /translation="MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAG
                     VKRCLDIGAGSGLLALMLAQRTSDSVIIDAVELESEAAAQAQENINQSPWAERINVHT
                     ADIQQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECIT
                     EEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGPDQNYSEAYTALTQAFYLFM"
     gene            51982..53316
                     /gene="srmB"
                     /locus_tag="ACHY1N_002389"
     CDS             51982..53316
                     /gene="srmB"
                     /locus_tag="ACHY1N_002389"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0000027 - ribosomal large subunit assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HFS4044689.1"
                     /translation="MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADDLEHKTALLVHLLKQPEATRSIVFVRKRERVHELANWLREAGINNC
                     YLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHVFNFDMPRSGDTYLH
                     RIGRTARAGRKGTAISLVEAHDHLLLGKVGRYIEEPIKARVIDELRPKTRAPSEKQTG
                     KPSKKVLAKRAEKKKAKEKEKPRVKKRHRDTKNIGKRRKPSGTGVPPQTTEE"
BASE COUNT        13281 a        14244 c        12837 g        13004 t
ORIGIN      
        1 gttttcgaga gccgttggta ctgtgccgtc cgatttgata tcgccaaacg gatttttgcg
       61 gcttaggtat tcaacagcaa accccgatcc cagcaattca acaaaaccgg gcagatcacc
      121 attatcaagc acatcccgtt gcgttttgtc acttacaaac tgggccagag ctgcagcaat
      181 aaagctggcc tgccgaataa ccttattgac ttgcgcactg gaggctttcc ctgctgtaaa
      241 tccagataaa agcgcgggca acgcttccca ttcctcctgc gatataacat tggcatttcg
      301 atccgttgca aacgctttaa agtcattttt cgccatcaga gtaatactcc ccatgctcct
      361 acatcaaaac cactgatgaa ttcgttatcc atatcaaaac caaaaaattt tgagccttcc
      421 gatggggttt ccaccgaagg tgtttcaatg ccacccgccc ataccccggc ggcttttact
      481 gtgagatacc cctgtttaat tgccgcaatt aactcacgcg atacatctga aatatcagta
      541 tcaggaaaga cccagaccga tatcgtcatg tcctggttat cgactatctg cattcgcagc
      601 ccggatcctg ctgttgccgc gtcaagaatt gccggaagcg aatcattccg tccgtcccag
      661 ttattaatcg caatcttcgc tttaagaatg acacgataag tttcatcgct gagatacatg
      721 tatcctgaat caggatcgta tggtccctgc cataccccct gatcatatcc aagcccgtcg
      781 gtatcccagc tgaaatagac accggagata ggctggctga caacacggct acgtccgatc
      841 cacaatccca gaatgtcaag ttgcacacca accgcagagt caatatcaaa tgcagtaatc
      901 agccctctgg tggcagccgc aacatcaata agcggccggg tcatcagatc aacatgcgca
      961 agaaatttag gtttggtggc gtggtagttc gtgattagtt cggtgtattt gctcatgact
     1021 ccaccgttat aacgatattt tccggggtac aggacgcaga ttcgttgtat ctgatatcaa
     1081 tgtttgatga cgacaaagcc cccggggatt tcccaatcgt cagttcctga atatcgtaat
     1141 agcgtgcatt cccgccactc accacgccaa gattcgccgg tgagtaaatg cgacttaaaa
     1201 ggaccgaatc accaatcgtc aaactattga tatagtcgga aatagcctgc tggatctgct
     1261 gccctatctg tgaggtataa cccgtaaaaa cttttaattt aatccgggca taaacaggca
     1321 catcactgga acgcgagaat ttgattacat ggggattgcc gtatttatcc ggaaccgtaa
     1381 cggatgttgt accgtgagtg gctgtcccct ggcctttatt ccctctgata gcctgagcaa
     1441 tatccgtcac atcaccgcca tccacaatta cagcaacaga gtgtggcggt aacccgttac
     1501 cgtcctccga accagtatcg ttttcataga gtttgtggcg ggttacaccg gtaacattag
     1561 aaacagcacc atccagtgct tcaaatgggg ttattgatgg caacgcaaca ctttgcgact
     1621 gacggatacg taactccgcg tcagtttctg ccggagtgcc cacagtagcc gcagcaggat
     1681 tagttaccga aacccagcca cgggttggcg tattaatttc agtgatagtt ccagccagcg
     1741 ccgccactgc accactgacg gaacatgttg cggtcgccat cactgtacca tccacgccga
     1801 ccactactga agcaggcaaa cgccatatca cattattact gtctttcacg ctgccattaa
     1861 tgatggttgt tccggcagtt cctgcaagaa gcaaatcaac cgtagagttc gtcgcgcctt
     1921 tacgtgaaat accatttatt ttcacgttac tggtcagtgc agccccatag ccggttgccg
     1981 gtgaaaaaca gttgtagaca gttatcgcca tattattggc atcatgaatc gccagcgcca
     2041 tcagagccac catctggccg tctttgctgt ccggttcgag gtaggcatca ctgccataaa
     2101 tctgctgaaa atagctaatc agggtgctga gtatcgtctg ataatcaggc gcactgatcc
     2161 cctccgcggt tacctttgca gataaaccga gagaatcaag gttcagagcc attacgcctc
     2221 cgatgtaaca gtcgttattc cataaagagt gtcgatttca gcggaaaaca tgacacgtcg
     2281 ggtcgtggta tctactgtcg tattgaaaga gaggattgat ttaacgcccc gcgtttcgag
     2341 gatgcgctta cggatcgcca ggttgtaggt ttccggcttc tgcttaccga gcacggactg
     2401 gatccacgga gtcccttcgg tggtgtcgag aaaccattgc ccataccaca attcgaatcg
     2461 cgtttttacc gcctgcgcca cggcctccgg tgagttaatc agccaggtgt catcaccgct
     2521 gccaaaggtg taatcgccat cggcgtcttc acgtctgtat cgcatcagtt taccccatcg
     2581 gtattgcttc caccgcgctg aacaccgcca tgagtgtgcg tatcatcgat tggcttgccg
     2641 ttagccttaa cgctccccaa gaactcaaca gcaccagtga tttttgaagc cacaccagaa
     2701 acaacagacc ccaccatgcc acccatccaa gttaacaggc catgaatggt tactttctca
     2761 gaaaaatcag ccagaggggc aaccacatca agaccacccg gagcgacaat tttaattttc
     2821 ctggtgtcag gattaagctc aaaataggtg ctgccgtcgt cactacgcaa ctgtgtggca
     2881 ctggtattaa taccgctaat cttcctcgcc tgcgactggg gaccgacaat acaaaacgca
     2941 tccgataaat catgcattct gtcatcgacc ggctcctgta tcccgccact ctgccaccag
     3001 aaatcaatac aacgatcggc aaaaacgaca agacactcat ccccggcttt taccggaaaa
     3061 gtcaacgtac agcctccgcc gcgcgggaat accactggta catccaccag caggggtaat
     3121 gtcgtcgact ggttgattcc atttgagtcc ggctcatagc ctttaatcgc aggttgaaca
     3181 accactgtta ccgtgtccgg atcaaatgac tggacgatgc cgggcataga aacacgcagc
     3241 gccgacatga cagagccagc aagtcttaca tcggcctgtt ctttgctacc aagttgagcg
     3301 cttaaagaaa cgggcattca tatgtctcca gaaagtaaaa aacccgccgg gtggcgggtt
     3361 cattattgaa gtttcattac tgcttgtttg cttctaacgc ttcagctatt cggcgaagat
     3421 actcattgtt tttaaatgaa accatgatgc actcaaagaa tattcggcaa aatacagcac
     3481 ataacaaaag cactaaagcg ccagcagcct tcccattaac aaacgttata atggcggcaa
     3541 caaccagaag taacattgtg atgccataca gaacgttgat gatttttgga gttattaatt
     3601 tatcaaatcc gaacatgtga caaattcctt atcgtgaaag tagaagtatc acattataat
     3661 tacgagtgat taatcaacaa tctttttgca tggaaaggaa ccgatgattt tcggtgcatc
     3721 catgctgttc tgcagaagct ggacgccaat gtaattcact tcaccttccg gcaatcatac
     3781 gtccagaact cccgaggctc gtccatattt ttgcggataa cttcaacgtt gaggatcgct
     3841 tttttgtttc gtttgatgta gtccatacct aaccaacgtc cagtattagg atcaggtaac
     3901 atccattgca tcatgacatt atcgaaatcg tctttttgtt tcaaaaaggt cattttttgt
     3961 gtttctggct tttgaccatt gatgtgcatg aggccatcat taccagcatc aaagcggaat
     4021 ggtccgcact gcgttgccgc cgaaactgtt aacggcaggg ccaagaataa acaaaaaaat
     4081 acttttttca ctctacatct ccgactttgt ccaaagtgcc ttttgccaat agttctttgc
     4141 cacctttagc caagcaaagc aggtccatat accacgcctg ccctcgggtg tcgccagtat
     4201 aatcaatgct gcccacaatg taatcaccgt cagtattaat gctggcaggc tgtgacatgc
     4261 ctgccagacc gttaacgtag agattaccgt cgctttcaga ctcatccagt cgtgctggcg
     4321 atttcgctac ctggtcatta ctcaaagagg cacggtatac agatgcctga tccagacgaa
     4381 taagcccacc gagcttaata tttggattaa tcagacatct gacatttacg ccagctccca
     4441 tcgtctgctg tggcataccg ataagcccgg tgttagcatt caacaccgta gcaacaccaa
     4501 tatatttatc ttcaggaaca atatttacca gattattttc ataccaccag ttagccttac
     4561 actgccctgc gatatgattc atcaaccttg atgtgttttg ataaacaacg cgaccccggg
     4621 gaaataccgt ttcaggcatg tcaggaactg cgccggattc gatgccatat ggttcgaatg
     4681 atttcatacc cagactgaaa agatctctgt acttccagcc agctgccact gtggttttca
     4741 cacttgcgtt caggtggcct tcccagctgt caatacactg caacatgatc caactgtctg
     4801 tggcattatc tttaccagtg acagtaaaac ggatatctcc attgaatatc ataccaacgt
     4861 tttcatcagg ataattacct gctgcatccg gttgcccctt gtatccggca ataacctgta
     4921 tacgcgaaaa ctccttctgc ataatccggt tctgagtggt aggagacagg ttataaacct
     4981 taaaatttcc aacgaatcca ttaaatatgg tcgcaggcat tttctgaata ttgaaagtga
     5041 ctttaagctc agaaattttt atcccgtcgc ccttatcatc aacaagcaat aattcaaagt
     5101 gacgcatcca gtttttcgac attgttactc cgtgaaaaca tagaggtgtg agagcgttcc
     5161 aagatcgaat tgcgtcggat tctcctgccc tgccacgtcg cagagcacca ccagagaaaa
     5221 acccagatcc atatatcgat actgtgccag caggtcagcc cccgtaatca tcggtatacc
     5281 tgatataatg gcggagccat tgctgtcagc aagatccaga acccagtact cgcctcgcca
     5341 gatgacagac aggtgataaa ccgaaccgtt aattgtggtg gcaaaagtct gattgtcagc
     5401 aaccagtggg atttctacgg ctttcatgaa tcaccttccc agaaataaat tgctcaaata
     5461 cccatcaaca gtggagatac cttcttgcgc catctgtggc agcgatttca gaatggaatt
     5521 attcggcggc accgttgttt tggtgcctgt attctgcaca gcagacgttc cgactccctc
     5581 ggtcatattg tttttcgggg ctaccctgac tgactgcgtg gaggtaataa tcacttccct
     5641 gagggtaagt gtcgccagaa gcacattttc actactctta tcggtcgtga cctccagcgt
     5701 ttttatcaac atattgttgt aaatacgctt gccggttgtc acatcgaaag gaatacgatt
     5761 ccgctgcagg ttaagcagtt cctgatacag ttctttcggg ctcagcccca gtaaactggt
     5821 agccgtcagg ttactggcaa aatcaagcag cgatccgcct ccggaaaaac cggtttccat
     5881 cacaacctca gaagggcgcc tgaatgcgtg ttctgatatg taaccagcgt cctcaccact
     5941 ggcaccagca ttcgtgggct gttcaaccgg atgttccgta atttccaggg cgtcagtgtg
     6001 cttttcggta ataaccacat caggaataat gattcctatt gagcgggttc gctgctgcag
     6061 taaaacagat aaaaagtcca ttacgcaggt cctttcaatt gctgtaccgc cctggcattt
     6121 acagccccct gcttgtcagc gatcagatta gccgcctcct gagggttgtt aactccatga
     6181 acatttataa cagtctgctg gttaaggctg ccagcggcgg cctgatacgc cagcgggctg
     6241 ttccagtttg aataaccttc tttgcgcgcc atcgactgca tcaatgctcc catagtctgg
     6301 ggatctgtaa gattcaatat tgcattcggt gatactccca tccatttcgc aacatcctgt
     6361 gcatactttt tcggatcgtt gttatcacct gccggggccc aggtactgac aatatcctga
     6421 atagtctgta atgcccgtcc ggttgttttc ccggtaaagt aacgcatgag ctggtttttc
     6481 atcgcctccc agccctcaag agctgattcg aaaaaccgga accctttacc gctcaccggg
     6541 cgaatgttcc cggggttatt gttgcgatca gcaagagtac cgccgccggg gatgtcgggc
     6601 tggacgttgg agccatgcac tacaccgtta ctctgtccct gccggataac tttaccgggt
     6661 cccccgtgca accagtccat ccacgcaggc cattcacgga cctcactgac atccctgcgt
     6721 ccgatatctg tttttatacc aatagcagcc agcgtgtcgc cgataattcg cttcgtatac
     6781 ctcagtgaag attttgcgct atcggcaata ttttctctgt cactaacaat atagcccgcg
     6841 taaagcgccc acaatttaag ccagggtggg accggtaaac ctgatatttt tccgaaagcc
     6901 cccagaacct tggataccca gacacccgcg atgaatgtac cgaggatttc cagtgcattt
     6961 tgccagccgc caacaccatc ttttagttcc agaaggtgat cacgaagcca ggtgatcgca
     7021 tccttcgctt tatctattgc cggttgccat ttttcccagt cgataagact gttaccgcct
     7081 tctttccatg ttttgtagtc ttcccacaag agaccgagag ccacgatcag accggtaatc
     7141 agccctatag gtgacatcca gaaagtagag ttaagtatcc gcatggcgac aaccagaccg
     7201 ccgataacct ctatcagggt tttcgtttcg gcatccagtt tcccccacca ctcgatgata
     7261 tctccgacac catcgactat ccgaaatgct acccgcccga ctatctcacc cagccagagg
     7321 atccccttta tgacctttgt gatggtgact tcaattttgg gaaaattttc aattatcttt
     7381 ttgcgcaggt tatcaatctg ccccgccagt ccgtccgcaa gattcgatcc gattttgtcc
     7441 cgcgccatcc cggccatttc accgagcgat ttcagcgagg tcataaaccg gtttgacgat
     7501 aaggcagcct gatcggcatt aaatccgatc gctttcacca tttttgaata ctgagcgctg
     7561 aactgcccca ctccgcgacg catagccatc agggtatttt cgtcaatgcc cagcatctgc
     7621 gcatactggt tagcccggta atacggcatg ctgctgagct tctggccgac gcccgtaaag
     7681 atagcggcca tgtcgcgcat gttaccgctg gcgtcacggg tctgtacacc aaggcgattc
     7741 aggaagcctt ccgccccggg attgttacga ataaaccggg agaggctttc cagagaagat
     7801 cgcgcagcgt ccacgctgcc gccaacctgc gaaaccgcat agccaataga ctgaattccc
     7861 tggactgtcg cgccggtgcg ctgtgacgcc cagtaaagat tatccatgct ggaggcgatc
     7921 ttagccgtga aggccaccac ggacagcgca gctccttcaa cggccagtcc cattttgatg
     7981 acatttgcag ttgtaccggc gaggacagaa ccgaactttt tcgctcctgc atcatccaca
     8041 ctgaagccaa gcgagacgag gaaatcttta atagtttcag cgttcattat cctctctcca
     8101 tttctcaatg cgccgctggt tatctgcttt taccgccaga tggtcattca agagagcaat
     8161 gtcatacaaa tcgacagagc catctttaag tgctgtatag ggaattaacc cggcgtcaac
     8221 cggattgaga aggtaggaca gcccgtccgg caggctgtta aacgtcagcc ctgttgcagg
     8281 ctctgcgtcg tgctggtaag gggtgtaggc aaaaaatttc ccagcgaatc ggcgaccacc
     8341 cgcgccacca gctgcagcat gaccagcagg tcaatatcat caaacatcag ttcgccctgg
     8401 gtaaataccg gcacccatcc gtccatatga cgccgcgata ccaccgcaag acagggatga
     8461 ataatcgcat cggtgtcatc ttcggtcagg gaagacagtt cctcagcgat acgcgggagc
     8521 atggtttcaa acaccggttt taattgctcg aatttcacgg tgtcgatttt gccgtcagca
     8581 ggcaaacggg agcgaatgct cccgaaatct gacatcattc ccgccagtac cggcagaagt
     8641 ttgcgggtca ctttcagctg gtcaaaaacg ctgagttttg ccacgcgata tttcacacct
     8701 ttgatttcga attccatgta ttaaaactcc ccgagaacct ggtcaatctt gccgcagtca
     8761 aacacccacg gcatcgtatt accggtttta gcgttggcgt tatccggttg tttctggaac
     8821 gcaacactgc gtgccgtgat gatgtcgccg ctgaccttgt tgcggatcac gataacgtta
     8881 ttcccccatg tggcagaaga ctggctctgt gcgttatacg ccagcgacaa ttttttattt
     8941 gtcggtgatg tcttcagaag gttaacggta atcgtcccgc ttttatctgc atggaggctg
     9001 tgcatcactt caccatcagc accgatggtc atggtgtttt taggaccgcc catcgcaacc
     9061 acaatcccct cttcagaact tgcagaaccg tacccgaggt caatcgaacc ggtcgggccg
     9121 gtcagcgtcg cagtgacatc cataaaagaa taggtagaca ttcacttccc cttagcgaac
     9181 aacgttaatc tgtacgtcag cgtaatgaac cgcgcctgca agttttattg cagcctgaat
     9241 caccggagcc ttacgggctt cacgttctga ttgtgcctgt tcatccagcg gctgggcgta
     9301 tacgtaataa cctttgggca gcgtgtcacc tgatgacaac tggccaaggt cgcccccgtt
     9361 ccatacgccc ggagcaatca gtccattctg aacggcctga tccagtgatt tttcaacatt
     9421 tgataacagt cgggtaatac cggcttcagt ctggggaact ttcgtggtgc tggtataaag
     9481 caggttatag aggttggtct gcacataatt ctgtaaccag tccaggccgt ggcgttcatc
     9541 aaagaaatcg ccgttagcca tcactccctg ctggaggata gctgtatcat tctggtagta
     9601 cacgaacaca ttgcagtttt ttgcatcaag tgccgatgcc tggctgactg tcagtgtttc
     9661 atacccgaca cccggctcct gcttaaactt gagcgtaatc gcggtattac tgccattgaa
     9721 attaaccgtg aacgcccggc caaatgcaga taacgcagcg tatttattac ccgatgaata
     9781 ctgaataaaa ctgcgtgaat atccggcggt tttcagtttt gatgccaaat catctctgga
     9841 tgcagtctgc aggcatttct catcgcttgt cgtaatcgcc agaatacggc ttacagaaga
     9901 ggattcgatc gccgcagcca ctttcagcca gtctgcatcc ggaatatctg catcgtctgc
     9961 aatccccagc ccataccatg aagtataatc aagcatggca ttcacagcct gctccagcgt
    10021 ctcaggcgtg gcctgttcgc tgtctccctt cgttttcacc caacgaccaa caaaaacctc
    10081 ctgaggtttc ggtgattgtg agaaaaacac ctgcgcagct ttatattctg gtgattccac
    10141 gccaaaatct tttccaatat cttccgcggc agaataacga cgaatgcgct cacttaccgg
    10201 aatgattgtg gacgggccga gaatgagtaa tgcaccaaaa tttcgccctg atgctgcacg
    10261 cggcgacatg atcacatcaa cattaacaac gtttgataca ggcaagccct gtgccatagc
    10321 ttaatctccg aaaaagatga ctggtgcttc caccagcgat ttaataccgt actcgcgcac
    10381 aaccttccgg cgcaggcgca ccgtcatatc gtagcggcgg acccattgct gattaataag
    10441 ttcagggaag ggagtcagac ctgtgtaatc gccaagagac agccccagcg cattcagtgc
    10501 tgcattgttc tgcggcacag atataccgtc acgaaaccgg gacgcataca ccatccccgc
    10561 cggaccataa aacgaagcca tacactcaat cgtttcatgc cgccagagct gagagccatc
    10621 atcggtctgt ctggtgaatg ccggactgtc atcacctgac catccgataa ccccaaacgc
    10681 acaccagttc gtttcaaccg gtagcagtgg cggctgctct ttctgccagc gcgggcgaac
    10741 catcccggca gacaggccgg aaacgttacg catccactgg cttaacagcc tgtcgagcgc
    10801 ttcgtcataa tccggatcgc cactggttgg tattaaccat ccgcgctctg tactggtgtt
    10861 attgctcaac cggagttccc ccatcaaacg gcatcaactc acaatgcgcc tgaacgaatc
    10921 cggccccata agctgtatac gggtcgacga aggtcacacg ataatcacgg ccctgatacg
    10981 tcacgatatc ggcatcacgg ccagtctgtc cctgcgtcag tcgctcagtc gtcacaatca
    11041 gaattgcacc actgattacc tgcccggcct gcatacgacg gttttccaga gagcgatcaa
    11101 cagtaacgac tccggcaaac tgctttttaa cttcgctgtc gctgccgatc ccgtcctcat
    11161 ccaccgtttg cacacggcgt gttacccaca aattgaagtc gcaaaaatcg gggtcaaaaa
    11221 gcacatctgt tacatcaaga gtcggcatct ttatccctca caacatgggt aatagctctg
    11281 cgatattgcc cggtgtcaat taatggtttc gccagatcgg ttccgggaga ttcgccagca
    11341 gcgcgccggg caagttccag tgttgccccc ttgcgccccc gacgagcccg ggcttcaaca
    11401 gtgctgtcag caagcggcgt aaagccggta atggtcatgt aacgcctgac gccattagcg
    11461 gccagcgttc cggcacggtt gagtgcgcgt tctgctcccg cagcattacc atcaagtgca
    11521 gcctgcgccg cggctttgag ctgcggcacc gtctgctctt ctgccgattt aacgccgggg
    11581 accaggtgag gtcgtggcgg gatgttctgc tctggtgagc catattcgtt gaggtaaccg
    11641 atgcccgcat taccaaacgg aacatcatcc cgcccgctgt cttccgaagg gatgccgacc
    11701 agcacatctt ttttggttaa cgacctgagc gcatccagaa tggccttagc gttatccacc
    11761 ctcgttgtta caccgctttt gaaactcata gctggcgacc gcctgcaccg aacatcgtga
    11821 tcaactgata aaattcagcg ccatatcggg tgttattcca gaaacctgca tcaggattca
    11881 gcgtcgcgct ggtgtcatag ctgacgctta ccttgtcaac ggactttgag gactgaacac
    11941 cattggttga accgcccgga ccaccagcca gcatcgcccg gctgtctgcc gcccagagcg
    12001 tcatgtagtg cgcaacgaac aatccggcaa agtacggaaa caactttttg ccggtgacat
    12061 tttcgctcag cagttcatcg gccagattca gacggaaccc gatttgggcg tcgggatatt
    12121 ttgccgggtc agcaaactgc gggaagtcgc ggcgaaaatc acttaccgct ggcagacttt
    12181 gattctttgg cattttttac ctcgttacgc gcgtctgtgg ctttgccaac ggatacttcc
    12241 gcgtgcgcac gagtgaacca gtgcgtggca acgtcttcct ccacagcatg acggccttta
    12301 acaaactcgc gccgcgaacc gtcgggaagc gtgagcacaa acggggtatg tacgtgtatt
    12361 actgcattat tttttgccat cgggtcatcc ttaatggccc cgccaggggg cccatatggc
    12421 tgttaaatgc catcaacgta cgaaatggtt tctttgtaca ctggctcaac cgcacccagc
    12481 ttgccgtagt aagtgacgat ctgatacaga ccgcgatact gcaccggcac gctctgaagc
    12541 ggaaccagcg ggtagcggac gtatttttta tcgttggtgt acgcaaccat gcgatccttt
    12601 ttccccacac cacggccttt cagccattta accgcgcgga tattcagcgg aacaccgttc
    12661 tggtgatagc tgatggtgtt ggtctgaaga tacgtcaaca gggactggtt acccgcagat
    12721 gaaacgatga tgctggacaa cagagcaaac tgctcaggcg ggatcagcaa atcacgcgga
    12781 accacagagt aaccggaagc ggcccacgca tcagacagca cctggttaat gcttgcgcgg
    12841 atttcgtccg gtgttgaggt cgcccacgtt ttggcagcgt tgttgacagg cacgccgtcc
    12901 agggtaacaa ggcctttcag gtttaatgcg gaatcgccaa catatacctg ttcatcgtta
    12961 tccatctgcc atttcagttg cataccgtca tacttctgcg tatcaatcgg gcggccgacc
    13021 tgctgagcag cctgcaattc tatgaccgtc cagccaagtt ccatccccca caggttcagc
    13081 gggttaccgg atttgccgat atccacgttc acgccagcaa tagcggttga gtctttgcct
    13141 acccagtttt tgccattcgg atttgcacca gtacccgcag cggcgaagct ggtattcgtc
    13201 cagctggaaa tgtcatctgc gatagagaca tcttcacgca actgaatatc gcgggtccag
    13261 gtgtacccca ccagtggcag gttcagcgtc tggtcgagtc gctccagctc cccgatgaga
    13321 aaggcaccag agctgtcaac ggttgcctga tcaaaagtaa tcattcgtct gttccttaaa
    13381 tcttccagga aatttctgca ttgccgtcag catcaccggc acctgtgaat tcagcgttgg
    13441 tcagcaccac atttttgcca ctgactgacg tggacatgaa tccacccagc ggcactttga
    13501 tggattcatc agtggagacg acaacgtata ccgggtcgcc ttttttgatg gtgctggcat
    13561 caaaatcaga accgagatta acggtcacgt agccacgctt catggcgtcg cccgggaagt
    13621 tcttgcctgt tcccacctgg cgaaccatgt ccggctgcga cgtggtcgga taagggcgca
    13681 cgtagatccc cttcaccttg tctgcggtat caccatctgc cagcggcacg aaaaaaccgt
    13741 catcatcgta tttaccagcc aggccatagg cagcgaaggc gttatcggat ttaaggacaa
    13801 ccggttcgac ggttaagtcc tgcgggcgag agacagcccc ggcaatgcca acaggcatcc
    13861 ggtacagaaa tacattattc attttttacc ctttacggtt tgcccagaat tcagcgtttt
    13921 gtttgttcag ggaagcgata ctggtcatgc ccatatttgg gcgctgtgca tcgccggtgg
    13981 tggcgcgggt gtttcgccct ttggcaatct cagacacggc attaaacgcc atgtcgaccg
    14041 attgtttcgg caatttgcgg atatccgcat caccgactat ctggcgaacc agcgttttgt
    14101 cagcagaagc cagaacctca cgtttgaacg cggtcggttt catcttacgg ctcagatcaa
    14161 tacccggaac gataacttcg gcacgccagg ctgagtcacc agtaatcgtg gtttcctctt
    14221 catcgtcctc gccgtcaccg gtcggattat cgtcaggctt attgtcgtta tcgcccgtcg
    14281 catttccttc cagcttagcc agcagggctt tcagtaatgt tttgaggtca tcatcactgt
    14341 cgcccgttgg acctccgccc atctctggtg ctttgtccgg tagcggttgc tgcggggaca
    14401 ggttgatgtt gagattaacg ccctgcggca aatccccctc atctcctgta accgatgcgg
    14461 gagccgactc caccagttcg ttcatggtgt cagcgtcacc cgttttgatg gccgtgcgca
    14521 tgcgggtcca ccagcttttc ttttgatttg ccattgtgtc tctgtctcca attgcacaac
    14581 gatttccggc tctgcctttg gggacaagag ccacatggtt tccggtaata tcaacctgct
    14641 cagccttacc cggctcagtc tgcttatatt ccgcgtcata gccacacgac acttcgcgca
    14701 ggccatcttc gatcagctga atggcgtttt cgtctttgac gataaggtca gccagcatca
    14761 aatcagactg cacacccgtc ccgcgccgga cattctgaag atgcccgacc gcgagctctt
    14821 tccagttctc tggattcacc agccgcacat ccccgttttc atcctcggga tgcaacaccg
    14881 tgatactcat tccttcgaat gaggcaagcg tggcgggatg gaatacctgc tcaggagaac
    14941 gcgtgacgac tatttcaccg aacttatcgg gtttcagttt tggcaggtca tcagcaccat
    15001 agagctgctt acctgttcgt cctatcggca cgtctttgca cagcaacgag ccgtcagcca
    15061 gctgatagcg ggtttccccc agccgggtat tgaaaaaata tttcatgtgt tacctgcgat
    15121 tcaggcgggg taagaatggg aggtgggaaa aacaatttct ttataacaac gacaattcgg
    15181 gaactcgcca gcgtgacctg tcatgccgtc aagcgttgga ggtttgcccc attcgacaaa
    15241 tttaccttcc atttcccgat gagaatgcct gacgtcacca tcttcggctg tacgccagat
    15301 ataaccattc gaaccaattg ccagcgcacg cgcctgatcc agcgcgccgg ttgcacgtcc
    15361 aagttcagta cgggcaatca ggtcagctct ggactttgct atatcacccg atgctgctat
    15421 ttctttagca aaatgttctg ctctcccacc ggtcacaaca gcttcaatcg cccgattctg
    15481 gatgtcgtac accctgtcag ccgcctcgag ggggagcgat ttgatgtact tgacctgttc
    15541 ggcgatgatg gattgcatca cctggcccac aggagcgctt tccacaagat tgcggagctc
    15601 gcgactgatg ttcttgctgt gttgccgcca aactttctcg ttctgccggg tcaggtccgc
    15661 agtaaagttt tccgcgacct ttgtcgccca gggggtgatg atttcactgt agcgttccag
    15721 cgcctcaata atttccgtga tactgtcatt tgaaccatcg tagcgaccat ttacgatgtc
    15781 tccgaccgcc cgcgctatcc tgcgtaggct ggttcgatag cggatttccg cctgacggtt
    15841 cctgcggttc gtcatcaggt tcgccgatgc cgggcggcgc ttcatcttcg gcattctcga
    15901 tgtcctcgtc ggtaatggat gccccgatgc cggttacgtc agaattttcg cgcaaatcag
    15961 tcatagcggc tttcagtgtc atcagaccat cacccagcgc cgtactgatt gcgttggtag
    16021 tgtttaacgc caccgttgag cgatcgacat cagacatttg ccagagcggg ttaaactcaa
    16081 acgtgaaatc gtccggcagc ggcttgccaa gctccgaacg atgcatgatg tccagtatcc
    16141 gccgcaccgg aagacgtaaa cgcctctcct gtaacgagct tacccggtcg taatagttgg
    16201 caaggtctgc atcgccggta gaaaatccct tcggggactg tccgaacaac cgcaccagtg
    16261 ggataccaac agcgccacta atctgttctg caaactgtga aaggatgtca tccagaccac
    16321 tgaagctgta ctgatgggtt tcaaacttat cccgcgagtc catgagagtc atgccttcat
    16381 tgctctggaa ctgtcgaatc aggtcaatat tcttcagcaa cgcttcatac gcaggaccac
    16441 caagtgcgat aagctcgcgt agcttctcca cgctgtaggt acgcaaatgc gctttgtaga
    16501 ccagctgcgc cgcgccgaca gtagcgctgt cgaacgcggt aagacgatcc cagatacgct
    16561 ctacaaccga cattccccat tcgttctcgg tcatcttctg ctgaaatggc agcgtgacgc
    16621 catcaaagcg aatcagtcga ctgtgatgaa tgcgccaggc aggaattccc gttgctgtgg
    16681 tcaccacatc gtaaaactca ggtttaccca ggtccgtccc catatcttta atgcggcggg
    16741 tcagtaccgg gtcaatcatc cagcggtcga gcgggagaat ccccttaaac ttgcccttac
    16801 cgatggtttc gggtcgcagc ggggtcattg gtgcctgccc ctcaatcatg atgaaaccca
    16861 ccgcgccgcc gtagaggcgc gaccatttca gcacgtcatt cagcgcatcc cagatttgca
    16921 actcatccag ttgtgattcg agaatgccgc gatcttttgc atcaatttcc gaagtgatgc
    16981 gaatgccttt gcgggtcata tcatccggga tagcatcgac cgcttcgccg atgatccagg
    17041 acgaacgata ggaccattcc accagcatgc ggttacgact ggtgaaatta gcccggtagg
    17101 tggatgctga gtgctggtta ggtgtctgca tccctacgcg ggcaataaaa ttctcataac
    17161 catcagctgt ggcctgcgca gttcgccgca gggcttgttt gtttcgtgcc atcaggcctg
    17221 tctccctagc agctcccaga tgttcagggc tgaattcatt ggggcatagt tgatcatcac
    17281 cgagtcggca aggtttggcg atcgggttcc atcaggctgt ttatcaataa ctatttttcc
    17341 cacaccatta atggaatagg tcggctgcga aagctcgatg atgagtttat ctttgagtgc
    17401 catgctactg ctgattgaga tgatttcgtc cgggttgtaa gccatacctt caaccacggc
    17461 gcgccaggta ttctgaaaaa gtttacgtaa ccgccaccag ctctgggctt tggcgttagc
    17521 gaagaagtcc ttgttcagac gtgcggcttg cccgttgtcc ccgcgaacag cttcatcatc
    17581 cggatcaaat accgcgccac tacctcgaaa cggtgtggca agtattgacg gtcgacgcgc
    17641 agcgttacgc agttcgttga tagcgcgtgc atcgccgcga acgccagcgc ccagcccgtc
    17701 ctcgtcaaag cgaaactctt cgaggttgtc ctgttcgcaa aagccgaaaa ccttctcgac
    17761 ggactgataa atgtcgctgc ccacaccgga ccattcccgc acattttcca ggaggaagcc
    17821 atgacgggtg gaaaaggcat ttttgtccct gccttcgtcg gcgacatcca tcgcgccaag
    17881 tcgtttgcct gttggctgga tacccagttt gatatgcgca tcaacggcag cctgtaccca
    17941 ttcggatgga atcaggactc cttccgctga tgcgctgtag ttcagatcaa gttcctgtgc
    18001 caccaccacc ggattatcga ttttctcgca ttccctgcga taccactctt catccttgcg
    18061 aggatcatcc cgccagtgga atgtgaatac cggtatcttc ccgccatgac gcttctgagc
    18121 gaacgggtta gccatgccgt taactgaact caggtcgata cggcaacgcg tcgtttgtga
    18181 caacgccgca tcaatcagca gaggacgctg aaggaatgca gcctcatcaa ccagataaag
    18241 cgtggtacgg tcaccacgac caatattatc gccagcctcg cctttgataa cggcaccagt
    18301 ttcaggaaac tcaacacgca tatatggcgc gtgcttcttc tcgctccacg aaccgcgaaa
    18361 ctctacaggt agcgtttcca cgaacttgcg tgccttccag aacaatgctt tcgggtcacc
    18421 agtgctgtcg acgtattcct ctttacggga gccgaaaccg ataaccattt ctttgttgaa
    18481 gagacaaagc gagcaggcca gtccgatcgc ggtccaactg agccccattt cacgggattt
    18541 ttcggtaata ccattctccc gattgcccca gcgttccata atccagtgga tccactcctc
    18601 ctgcttaggg aagagtaaaa acggaatggt caccggcagg ccataatcaa tattacgcgg
    18661 gtccgttgtc atgccccagt cgatgatgaa ctgagccgga ttggttcggt aaaactgctt
    18721 caatacgggc aatatttcag gattctggcg aatgcgctgt aggcgttcca tccgccattc
    18781 aaaaaccatc tggtaatcag gatgtttaaa atcgaagggg aatggtaacg gcatacttag
    18841 cccatcattt ttctatacgc ctctgcagcc tgctccggcg ttaagttggt aatttctgtt
    18901 ctgacgggtc ctccatcagc gccagtcact tcatttttga cgttgtcttt aaacgcctga
    18961 acagaaacat gacgcccaag caactcaagg tttttaacct tatcaggcca cttaatcttt
    19021 ttaaggatcc cgaccatttc tctgtcatct cctcgcccct caaacatttc agcgaggtta
    19081 aatccactca ggtaccgacg ccacgattcc ggccacgcag acagaggctt aatacttaaa
    19141 tcgtcctcca ggatgtcagc cacatcgagc ctgtcgatct caaccagtcg catcagcaca
    19201 taattcgcat caatgcccag ttgatcaata cgctcctgct ttagctcgtt aatacgggcg
    19261 cgtatctcag gtttaccgta tagttcagcc cccgtaacat gtgctcgcct ggagacgtag
    19321 cctgcgcgaa tagctgcttg tgtagcattc agatcgacaa gaaactcgcg acaaaacacc
    19381 tcgtgttttg ctttcagctt cttagtcatt ttattttcca gttatcaggt cattatcgaa
    19441 gcccctcctg gaagagcttc tgtaatgcta ttaccgggac tgttctattt gtcggacacc
    19501 agccaactgg ttattcgcct tctcgatggc tgccaacagt gggttaatcc acagaacagc
    19561 ctggcaatat gtcaacgttc tggtggtagt ggcacgatca ccggctgagt caatgtcccc
    19621 ggaatcggcg tgcaatgcgc tggcgcgtaa acggttcgcg tagttgagca acccgacagc
    19681 aatatcaaca ggaacaggga aatcacagtt cttttcacgg agcagaacct cacggtattt
    19741 gatgactgtc ttctcgtgac cgatgtcgac cagagaattt aatcggcttg cgttttctgc
    19801 tatctggtta aaacgattga agtttaatgc ctgattagct atcactttcc cttgatattc
    19861 aacttcacct tccgctttat cagcccgcaa cttttctgcc tgatacttgc tgtggtaatg
    19921 gtttgcagac cagacgagcg ccccaaagac agagaagaaa aatgccgcga tgacaatctt
    19981 ataagtcagc ttcatttacc accccaccag catctttaaa cctggaaatc aggtcaccga
    20041 ttttatgttc atactgaccg taacctgcac caggtaacga cgcccagata ttgctgcaac
    20101 ggtcgattgc ctgacgaata tcgccacggt caatcatcgg taaagcgcca cgctctttaa
    20161 tctgctgcag cgccacagcg tcctgacttt ctggcgaaaa atctttcagg ccaagctgct
    20221 tgcggtaggc atcccaccag cgtgaaagaa gctgataccg gcctgcggct gttgatttaa
    20281 gcttcgggtt tagcgtgaca agtttgcgag ggtgatcgga gtaatcagtg aacaactcac
    20341 ctccgacgat aacgtcataa ccgtgattac gtgtcggttg tcgcccgtta tccgttcctt
    20401 ctgaccatgc caccatatcc aggaaagctt tacgttggga atttagtgtc tgcatgaatt
    20461 actccttaga gccaccaaac ttgttaccga ttactcgcat tgcagcccca cgaatagcat
    20521 cgacaccgat cagcccaaca ccaccaccaa tggcaacaga aagcgattta ggccatccga
    20581 catactcaag agcggatgca aaagtcagcg tcagagcacc acagagcaaa atctcaagcg
    20641 tttttcgttt ccagccgccg ccaccgccaa aataggcaat gcgcaagcca gccataacaa
    20701 ttgacataac cactgcgccc aacggcgtat ctccacgcca ccaactttgt aagagttcca
    20761 gtaagtcagg ccaggaatga ggagcattgt gcattttcat accgcccacc tccgccatta
    20821 cggggtgttg ttgaaaggcg ggccctgcgt atacgcccgt aggattgggt tatgagccgt
    20881 ccttcggtgg gccctgaata caaaaaaagt tcgccatagc gaaccttgtt aaatttgtta
    20941 aaaaaggaag ttatttaaca taatgtacgt tataggaacc acacgatcac cgctcgcaat
    21001 agatttgcga tgaaaggcct atttaatcaa cttaagtggt ccagaatgac gaaattcgag
    21061 tgaataaaag gtgcataaaa aagggcaaaa actgcatagc gttttttcgc gacgaaaacc
    21121 ctgttttatt aacttttact gagaatagag cattaaaaaa gccccaatga tttggagctc
    21181 ttcgttgagg tcagaaattc aactcatacc agcgtagcgc agtttttgcg tagcgcacta
    21241 atactttttt catccctttg aatttcgacc tcaggatcca tctgaaggct cacacccagc
    21301 atgcagagac acccctcaat gaatccctct gctacctgca actgctggcg gataaatcct
    21361 tcagaacagc gacgccgccg ccctatctca cgtttgctta acccgtagac gtagtacagc
    21421 ataatgacgt ccagttcctc aggcttacgg acctgctgca gccgacagac gcaagcatcg
    21481 ataatcaggc catcgtcgtc acagcaactc agcctgccag gcgagctgct gactaccagc
    21541 cctttaaatc ccgccgctat tggagcccag ctcactgtgg tgttgctatc ggcagcccat
    21601 ccaccccagc gctctaaaac ctgttgaata ttacgcatag ctctgacctc tacgttttgc
    21661 tacgaaaaat ttttctgaga actacgtctg tttatccgtg ggtgtggata acgcagttcc
    21721 gatccgcata ttgcatgtat caacatgcaa aaagttgcta attcggagtg gaaccacctg
    21781 cccccacctg gaaccacctt ttcctaacct ttccctcaat cgacttatat atatatatgg
    21841 ggtttctagt agaaaggcgg ttccagtggt tccagtagtt ccgccccgct tgccacaagg
    21901 tctgcaaggt ggaaccacct tctcttctag gtggttccgc gtggttccag cggttcccaa
    21961 accttgcatt ttttcccccc aattcgcctt tgggcacgct tatacccgca attttgcaaa
    22021 acattactaa ttcgcatttc ttcgcgtttt ccgatgcggt caggatttag cccaatcgca
    22081 tcacgcaaaa catcacttgc gcgtaaaaat tcgcaatttc gcggaagttc attagtcatc
    22141 aggtcgggcg tgtcgagcca tttctctatc gtttcaagcc aagcatcctt gatggtgtac
    22201 tgttcatgga cactcgctgc cagttgttca gcctcacgga actggatacc ccccagacgc
    22261 tgaaacacct cacgagcctc agcccaaagt aaaagaagat ctctttttat cgctttcacg
    22321 tcgactttcg acacttccac ggggagccag cgacggttac cagtcttgtc cgcaaggaat
    22381 tcgtcctcat tagtggtacc aacgaacacc aggcgacgag gaaactgggt ggcgaactcc
    22441 cggtatttcg ggatccagtt ttcgtgagta cgcgtcacaa acgctttgat tgactccagc
    22501 tctttggtat taagtccgcg cagttcacca atctctgcca ccagccgacc acgcattttt
    22561 cgagcgagat catcgtcttt ttcggcaaaa gagatttcag taaaaaacgc aggatcaggg
    22621 ctcagtgcct ccactccgga agacttaccg cagccctgcg gaccaacgag gatcggcacc
    22681 atatccgctt tgatgcctgg ctccagtact cgccccgcca acgcggtcca catgtacata
    22741 gacaccgcac gggtataagg cgtgtcggcg gtaccgaagt gcgtatggta gaaacattcg
    22801 atgcgcggca cgccatccca ctccagcccg ttcagccagg tgatcgctga atcgaatggt
    22861 tgttcatcgg ctgcaagtaa caccacatcg cgaataagtt cacggccaac aggtttaaat
    22921 ccccgctttt ccatcgtgat gcgcaggcgc gcataatccg catcggtgaa tgcccgccat
    22981 tgtccggatc ctgccggggc aaacatgatt tcgtcgcgga actggtcaaa gcgaatatcg
    23041 atgtccacaa aatcagagcg tactactgct ttggctgcat tgctgatggt tgcctcgata
    23101 cgcccccatt tatcacgctc gaaagcaggc agcggtaaag gttccgccac ttcgatgctg
    23161 gtcagatctt cgaaatcgtc gttgcggatc ccgatggcat tcaggaaatc tccgtcatca
    23221 cgatgcgcgc aactggcatg caggcattta aaatgcccct gctcaaagcc tgcggttccc
    23281 gcaggaaaat aaactgtgct tgttggatcg cctccgctac tgtggccgtc ttcaaacgga
    23341 cagcggatat atcgttcacc gtttgcgcca tccagcagcg tccagccatt ggcatcaaga
    23401 tattcagctg tatcatccgt cgcgccgggc gtgaatgctg aacggtcgcg catcttcgtg
    23461 ttgcccgctt cggtggttac cgacacaggg agttgttcag ccaggcgctg ccacagcgtt
    23521 tcaagctgct cacctgtaat agccggaggt tcatccggca aaccaccgtc ccattcaata
    23581 cgcgcgccgc tgctgtgcgt accacaggca acgaactgct gcccgttcgc cagcaactcg
    23641 ataatgccca tatcccccgc taggcgatgg atacgcttac ggaaatcacc atcaacggcc
    23701 agcagataca gacacttatt actgtttgct cgccagcgtc gcggcggcga ctcacccaga
    23761 agttgcacaa gtgttttgcg aatatctgcc tgaatgtctt catcttcgct atcgcagtcc
    23821 agcgccagcc agccatggcc tgtacgcacg cagatgccat aatccggttc attcgaccag
    23881 cgggcaaaat catgctcagt aacaacatgc ccggtccatt gagcaatacc ggtgacctgg
    23941 cggtcccggt tatagcgact cggcgtctta cccaacgctt tcaatttact atcaggggat
    24001 atggtcgcac tggggttaca tacaactggg agaagatgag cagtccgccc caataccagg
    24061 tcgaaatgaa accactcatc aggcgtagct ccccatggtt tgctatcgga catgggttac
    24121 accttttgtc tagctgtcac ttcctgaaaa agtttttcta tcgcacgtac tgtagaaaag
    24181 cgagggtcag aatgaacccc ggtaagaagc cgactaatag aagactgctt cacgcctgca
    24241 atttcggcaa tttggttttg ggtataccct gaatcaatca agcttttgac catctcttgt
    24301 ggtgttagtc cggacatatt taagtctcca ctttcgtcta tagcgcaaat ttatacgaaa
    24361 acggattact cagcaatacg gcaattctat gtcatcctag attaaaatat ccgataacgc
    24421 ataatcaccg tccctgtata caacatggat gaatccaaat gattgatact accgatatcc
    24481 tttctcaaaa catcaagtac ctgatggaca aagccaagat aagctcgata actgagctgg
    24541 cacgtcggtt acagctgaac caaccaacgc tacacaggct ggtatcagga gaggtgaaag
    24601 atccgaaata cgcaacgtta aagcagatcg ccgactactt ccacgtgtca ccaatagact
    24661 tggcagaaag gagccttcaa gaaatggaga aagaggacgc gacaggtata aaaacgtata
    24721 tttctcttag gtttaataaa gtacctgttt tgggaaacac tcagctaggc gttggaggac
    24781 tttggagcga cacccaatat tcagtaggta gcagtgatgg tttcatatac tggccgacaa
    24841 aggatgaaga tgcatacgcc ctgaaatgtg ttggtgattc aatgatgcct agaatcaaag
    24901 agggggagtt cgtaatcgtc gaacccaacc acgactacac tcctggtgat gaagtacttg
    24961 tggttacccg ggaaggtgag gtcatggtta aaaccttctt gttcgaacgc gatggcctgt
    25021 tccatctaat gtctgtaaat gaagatcatc caccagtcag agtaccacgc gaaaacattg
    25081 aaaaaatcca ttacgtggcg gggatcgcca aatccgcgct acgtatgtac taacctttac
    25141 agtctgataa cttacttctg atcaaaccgc tctccacaag ggcggttttc ttatttgcaa
    25201 aataattcat tttcgtattg acacaaaatc ccataacgca tataaatacg atatcgcata
    25261 attaatgcgt tttttaatac tggctcttta acaaactgaa ccgcgtgaca ggtaagccgc
    25321 agtactcctg gcaaaacgaa atagcacccg atgggatcga ggtaagcgcc gagtccgtat
    25381 gcgtacggta agcgtagagg acaacaccgc gacaaactga taagtcacgc aagttgaaac
    25441 gccccgacga tggggcgctt agttccttta actctgggtg gccggaaggg tacccatgct
    25501 taaagaaatt actggttgta aggatcgtaa tccgtgattg ccttccccgg attttcatct
    25561 tcagaaggca gtcgggcctc taaagcattt cggttgaaca gataggaagc cctacagtac
    25621 gaacaaacca tattaacggc tcgcccaagg cctggcttag taaccagacc ttccgcttgc
    25681 aatatagatt ttctcttttg ctcgtagcaa ttgggacaaa tataaaccgg agattggtca
    25741 gcatctgcag aaagcttgct gcgatagacc agagtacccc gcataggctg gtaaagttca
    25801 tagctcgccg cttcagcggc ccagttctct tgctttactt tctcattttc cagttcaaca
    25861 attttctcct tagccgcaat cagcagctcc tgaagcgaca tttgctgcat ctgaacatcc
    25921 attagcttat cgagtaagat gtgcgtcttc tctttaactg catagtcgac agtcagattc
    25981 tgaatctctc ttgctgctcc aaccgcgctt ttaattgctc ctcccacgcc ggataacgat
    26041 tcagttatcc gggaaagaat tcctttttct tcagacatat ctaatctctc tcaaactgta
    26101 ggggtgaaga gatattagac gatttctcac tgtaggggta caaggagaac cacctcgcct
    26161 gatgtggtta aaagcaggca ctcgatgata tccatgtaat tgctgtgtgt agtctttgcc
    26221 cgcctcaagt gacgggcttt tttatgtctg aaagcgcact cgcaacagcg tgctccccga
    26281 tatgaaaaaa ggaatacaac cgatgaaacc tgaacacatc catcgactga cggggcgcga
    26341 tgttctccgt tatcgccgta aaaacttcga tttgatgacc ggtctggccg ttgccactgc
    26401 gctcggtctg atcatcactt tcattctcct tgtagcgagg accacagtat gagtttagaa
    26461 accagtctcg aacttaataa tcaacttcta gcacaacata atgcgctgct tgaacgtctt
    26521 atccgcacaa tggcatcagg tattgttatg catcctgaca cgatttcacg agtgcaggaa
    26581 tgtcgggata cagcaactga agctgaaaac atgtcagcgg caatgacact ggatgatctg
    26641 gagttcagcg acgttatcgc actggctgtt ttctacccgg tagccacccc tatcacagaa
    26701 gacatgctgc aacgtgctgt tgcctaccgt gatgctgaag gcgataaacg agtagttcag
    26761 attgatgctc tcgacagcgc attacagggc gtcaaacgag ccagggcgct gcttaaacct
    26821 gctctcctgg acctgtcccg taacattctt aagttctggg acgacctgcc aaccatcggc
    26881 gagcgacgtg cttttgccga gcagctactt gatgcacctg cagatgggcg tgatgaagtt
    26941 aagccgaaaa aggccagtaa caaagatgga gaacgcacgg ggccgtttta cgtcaaaaat
    27001 gtatccggca cagcagccag tgaactccat accttacgca agttgaacga gatgcttaaa
    27061 aaaggccata tcgagatcaa ccgtgttgag taccttcagc tgcaggaaga atttgcacgt
    27121 agagacgcag caaattccag ccagaataat gacgccaaag atgaccatac aattgatttc
    27181 gcggcactac gcaaacaagc tgaagggttg atcctccagt tagcaaaagg gggttaccgg
    27241 gcagaagcta ttgcaattct ggaaaaacag ggagccagga aacttggtga agtaacggat
    27301 gaaaatctcg ctgaagtaat caccctggct gaaaaagcac tggagggtta atcatgccag
    27361 acgttcatgc acaactttct ccatcatcag cgcatcgatg gatgcgctgc ccaggaagtc
    27421 tggcgctgga ggccacacaa ccggataaag aaacaacttt tgcaatcgag ggcactgcag
    27481 cgcacgcgct tgctgaaaaa gttctacgaa acaggcaaag ccacccggaa cactacgccg
    27541 gatgcaatgt ttctatgttt ctcggctcat acccccttcg cgaaaatcct gatgatacat
    27601 ctggcccaca ggtggatgat gaaatggtcg aagccgttgg ccggtatgtt gatacggtct
    27661 ggactcttgc acagaataat gaactattgg ttgaacaacg tgttgatttc tcacatataa
    27721 cgggtgtgga agaatctttc ggaactgccg acagcataat cattgctggt agcgaattac
    27781 aaatccacga cctgaaatat ggcaaaggcg tccgcattga tgcagaacaa aatgagcaac
    27841 tacaactgta tgctctgggt gcgctcgaac aattcagcat gctgtatgac tttgagactg
    27901 taagattatt tattcaccag ccgcggctta accacgtttc agagtgggct ctgacggtgg
    27961 aagagctcca ggcgttcggt gaacgggcac aggaggccgc aaccagtgcg atccttgttc
    28021 tcaatattgc tgaatgcgaa ggcattgaga cactaccgct ggaaaacttc atacctggag
    28081 aaaaacagtg ccgcttctgt aaagcaaaag ctatttgcac tgcccagaaa atgcagcatt
    28141 tacaaacagc ggccagcgac tttgaagatc tgacaaagcc tgtcagcgaa ataatcacca
    28201 atgccagcgc acgtgtacct ctgttaacca ttgagcagct tgcggagatc tatagccaga
    28261 ccgactttat tgagtcctgg ctaaaggcag tacgggaccg ggttcacaat gaactcaatg
    28321 ccggacatcc ggtaccgggg tttaaactgg taacaggaaa acaaggtaac cgggcctgga
    28381 gtgacgaaga ggcagctcgc gcacttctga aggaccagtt caggtacaaa actgaagaag
    28441 tattcgactt taaacttatt agtcccacaa aagccgaaaa acttatcaaa aaggccagtc
    28501 cgcgccgttg gtcaaaagtc gaggcactga taacacgagc tgatggtaaa cccaccgtcg
    28561 ttcccgagtc agacccacgc cccgcactca atatcaaccc tgtaaatgat ttcgacgacg
    28621 tatccgacga tacgctaacc gcagacctta tctgatttaa ggaaatcccc atgaaactga
    28681 agctgaacaa tgttcgtctg gccttcccgt ctctgtttga agctaaaact gtaaacggcg
    28741 aaggcgatcc gcgtttctcc gcagtatttt taatgtctcc caaacaccca caactggaag
    28801 aaatccgtaa agctatgaag caggtagcga aggaaaaatg gggggagaag tgggagtcca
    28861 tttataacca gctggagaaa aaactcaatc tgtgcctgca tgatggtgat gaaaaagcag
    28921 agtatgaagg ctttcccggc aatttcttcc tgaacgctgc taacaaagcg cgcccagctg
    28981 ttcttgatcg cgatcgttcg ccactaattc aggctgatgg acgtccctat gcagggtgct
    29041 atgtaaacgc cgttatcgat atctgggcac aggacaataa tttcggtaaa cgcattaatg
    29101 cctcactcgg cggagtccag ttcctgcgag acggcgatgc attcgctggc ggcggagtgg
    29161 caagcgctga cgatttcgac gatatcagcg aaggtgctga tgctgaagca ctaatttaaa
    29221 aatattcatc ccccagctac gtgctggggt atctcatgag ggaaaggata atgtcacagc
    29281 ccgtattaac taatcacctt aaaactcaaa tcatcaataa cgcacttgag aaagcgggta
    29341 tccccaaacg taaatcagca ctacgagctg ctcgtgttga atgggccgaa cgtgttcggc
    29401 ttgcagctat cgggggcgta gagaaagaag ctgaaatatt aaaaaatata aaaaagattg
    29461 aatccatggt aacaaaaatc cctgattcat taaaaaccaa tagttcttta attcgaaaag
    29521 attgctgcat atatctcaat ctggctggag ccagagcaaa catttatttc aatggcaact
    29581 acagaggtta tgaatcagga gcccccgagc atattaataa aatagcacct gcagaattta
    29641 ctctacttgg cgaagatcct ctggtaacgg agttttatag ctttgatgct ctctacacac
    29701 aaattaaaag tgatgaaacc gaaatcatac agaacgtcag cgcggctcta aataaagttc
    29761 ggacagtaaa acgattactg gatgtatggc ccgaagctaa agaactgctt ccaacagacg
    29821 caccgccagt ccctttagca ccagcagtac atcgagagac attaaatgaa atgataggcc
    29881 ttcctaccaa tacagtgtct gatactcaat aacaaggggg atgcttatta tatgattttg
    29941 aacgttttac aatctcgtta agaggcgtga aatcaaaatc tctgaataac acatcaggat
    30001 acttcgctct tgctttatcc agcaggccag ttaaagtatt ttttgtgtta cccaacattg
    30061 tattaaccgc cactacatgt ctaatttctg gaggtttatc tataccacca gaaattgctt
    30121 cattaagaac cgacgccagt ggggtttgtc ccttacttgt tgaatcccac agcgtcatta
    30181 acagacgagc tgcgtctata aatagctttt tgtcagcatt tggcttgaca gtaataccgg
    30241 aactaccaga gccagaaccg gaacgttcta ttgctgcact ggtatccgat ttcataggat
    30301 taaataacgg cagctctgta caaccgatac gccgaatgaa atcctttgca acatctctac
    30361 cacagaaaaa agcccctgta caattttcat cagagcgttt tttaaatgaa aaacaatagt
    30421 actgatcggt taacggataa ccggaataac tggttttagt ttgtccagta ataagtttca
    30481 ggtgtgcaac aggctgaata ataaaatccc gaactatcgc atcttttatg tcgttaccac
    30541 ggtgacaata atattcaggt aatccattag gctgtctctt attacccaca gtcattagtt
    30601 gcctccttta attcatgata tctagcattt aaccatatac catatgagga tattttatgt
    30661 ccaatatact atggggcgac ctggaaacct attgtgacat tccgatcaac aacggtaccc
    30721 atgcgtatgc cgaaggcgtt gaagtgatgc ttttcgcatg ggctatcaac gacgggccag
    30781 taaatgtgtg ggatatcact gccggtggtg gtattccaca cggcttatac gaagcaatcg
    30841 cagaccctga aaccctgctt tatttccata actctcactt cgaccgcacc gttctgcgtt
    30901 atgcaatgcc gcgactggca ccgccagtcg aacgttggcg cgacacgatg gtgcaggcgc
    30961 tggcgcacgg tctcccgggg tctctggggg aactctgcga aatactaggc gtcccgcaag
    31021 acaaagcgaa ggacaaagaa ggtaaagcgc tgatccagct gttctgtaag ccacgcccga
    31081 aaaacagcaa actgcgtcgg gccaccagta aaacccaccc ggaagaatgg cggcgctttg
    31141 ttgattacgc cggactggat atcgaggcaa tgcgcgaagt ctataaacgt ctgccgaagt
    31201 ggaattatca ggggacagag ctggcgctct ggcatcgtga tcagcagatc aacgaccggg
    31261 gcgtctgcat ggacatgcaa ctcgcgcgcg ctgcgatcga agcggtagac caggagcaaa
    31321 agcgcttggc aaagcgtaca caggaaatga ctgatggcga agtgcaggca gccacacaac
    31381 gggacgcgtt gattaagcac atcgttgaat cctacggtgt ggagctacca gacatgcaac
    31441 gcagtaccct ggaacgtcgt atagccgacc ccgatttacc atctgccgtg aaagaactgc
    31501 tggctatccg cctgcaagcc agtactacca gcaccagtaa atacaaggca ctgatgaaag
    31561 gcgtaagcca cgacgggcgc ttacgcggta cgctacagtt ctgcggggcg tcacgtaccg
    31621 gtcgttgggc cggacggcta ttccagcccc agaaccttcc ccgcccttca ctaaaacagg
    31681 aacaaataga cgaaggcatc gaagcactga aagccggatg tgcagacctg ctgtttgaca
    31741 atatcatgga actaaccagt tcagcgttac gtggctgcat tatcgcgcca acaggcaaaa
    31801 aactggtggt aagtgacttg tcaaacattg aaggccgtat gctggcatgg ctggcgggag
    31861 aagaatggaa actgaatgca ttcagagagt acgacgccgg aacgggtccg gacttatata
    31921 aactggcgta tgcaaaagct ttcgatattg caccagatga tgttgataaa cacatgcgtc
    31981 agatcggtaa agtcatggaa ctcggtctgg gttatggagg tggtgtatcg gctttcatca
    32041 cttttgctct ggtttacggt ctcgatctcg acgagctggc gaacgccgcg ctgccaaaca
    32101 ttccccgcga tgttatccgc gaggcgaaaa gctggtacga cgaatcggtt aaacgtaagt
    32161 cgacctttgg cctgtccgag cgtgtattca tcgcatgtga ctcgctcaag cgcctgtggc
    32221 gcagggcgca cccggcgacc tgcgatttct ggtacgagct ggagcgcact gtccgcacag
    32281 caatcgccac accgcaaaaa acattgtatt gcggttatct taaaatccgc cgcgatggcg
    32341 cgtggctgcg catacagcta ccatccggac gcgctgtatg ctacccgtct ccggttatcg
    32401 aacaagggaa tatcacctac atgggtgtta actcttattc gcgtaaatgg caacgactca
    32461 aaacctacgg cggaaagctg gtggagaacg tcacccaggc ggccgcccgc gacgttctgg
    32521 ccggaaacat gccgcttatc gaagatgccg gttacagcat tgtgctgacg gtacacgacg
    32581 aggtgatcac cgaatcacct gacacagaag atttcaacga taaagcgctt tccgcgcttc
    32641 tctccactaa ccccgaatgg gcgcccgata tcccactgaa ctctggcggt tttgaggcgt
    32701 accactaccg taaggattaa ctcctatgtc atttaaatac cgggataatc cactttatta
    32761 cagggctgca agggaggctt tgcgacttga acaatccggc gaatatgacc gggcagcgaa
    32821 ggtctgggca aaagccaacc gcgaatcaca tcacgaactg aatcaggaat ggagtgaacg
    32881 cagatctgat ttttgcctga tgcagaatat gcgtgaaaag cgtaaggcgg tcgaagaatg
    32941 atcgtttacg ttgccgggcc gatgagcggt tacgagcaat ttaaccgccc ggcctttcat
    33001 tccgcagcaa agaggctaac ggacaaggga tatgttgtgc ttaaccccgc aactttaccc
    33061 gatggtttga cacaggctca gtacatggac atctgcctcg caatgcttcg ctgtgccgat
    33121 acgatttata tgctcaaaga gtgggagtac tctgccggcg cacgtgcaga aaacgcgttg
    33181 gcagagaaac tggaattgaa tgtgcttttt gaagagtggg attcagatgg cctatgaacg
    33241 tgagagcctt atcgaaaagc acctcgtcgc tgaagtgaaa aaggctggcg gtgtggcctt
    33301 taagttcgta tctcccggtc gccgctcggt accggatcgc attgttctgc tacccggcgg
    33361 ccgtcttgtt ttcgttgaat gcaaagcacc cggcaaagca ccacgcgccg accagttgcg
    33421 cgagcacgag cggctgcgcg agctgggctt taccgtggtg gtgctggata gcaaaaatct
    33481 ggaggggata ttgtgcgggg agcctattac aacgaaatag accctaacgc agcacaatgg
    33541 ctgcgtaacc ttattgctgc gggtcatatc gccccgggtg aagttgatga aaggagtatc
    33601 gaagatgtcg caccagacga cttgcgcgga ttcacacagt gccatttctt cgccgggatc
    33661 ggcgtctggt cttatgctct gcgtctggcc ggacggccgg ataacaaacc ggtctggaca
    33721 ggaagttgcc cgtgccagcc tttcagctcg gctggtaaaa gcgctgggtt tgatgacgag
    33781 cggcacctat ggccagcact attccacctc atcagcgagc gacgccctaa gctggtattt
    33841 ggcgaacagg ttgcgggagt caatgcctgg ttcgatcttg tacaaactga cgtggaagca
    33901 gtggactacg cctttgggct tgtcccgttt ccggctgcgg gcgtcggtgc cccgcatatc
    33961 cgagatagag cgtattgggt ggccgacgcc agcggcgagc gaccacagcg gtggcgaaag
    34021 cgcctcaata gcattgagga agatgtctgg agatcgtcga ccgtccggca acacgctaca
    34081 cagctccctg cgggattttg ctcacctggc ggggtggtac accccaacct gcaacacaaa
    34141 cccacagccg gagacaaaac gcggtctaga aaccttagcg gggctatcca gattagcggg
    34201 atggccgaca gtgacgacgg tcgacaacaa ccaagttcgt ggcgagggcc cagcagccaa
    34261 tcataccaaa cggggaacgc ccctcggcgg cccaatacga ttaacagctg ctgggatgat
    34321 gctgactggc tcctctgccg ggatggtcgc tggcggccag ttgaatcctg cacattcccg
    34381 ttggctcatg ggattacctc cagagtggga cgactgcgcg cctacggcaa cgcgatagtc
    34441 gcaccagctg ccgcaacatt catccgctcg tttatggaat gcgcaggata cgacctcatc
    34501 tgttgatatt atgggttagg taatgcacga ttattaaaat tatcaataat ttgcaacgcc
    34561 gccgtttgtc cgccagccaa tagccctgct ttactcagaa ggtatttagg gaatttggtt
    34621 ggtaaataaa ccgcacgaag ccagtgcctg aatacagcta aagcattatc agggtatgca
    34681 tagaccattt ggggattact tgcggattgg ttgaattctt cagggtaata gtgctggcag
    34741 cgttgtcttg ggccaatcgt cgcatcgtag ttggaagaag accagtagcg agcccagtgc
    34801 tggcccacac tgatatccgg tacagtgtac tggtttactg ctaatccagc atggatgagg
    34861 tctaccatta aaccggcaat ttcattgaat acaatgaaat gtccagcagg aaccgagttt
    34921 gccccatgca tgattgacac acgagagtgg taatgacgcc aagggtcatc aggtatgtag
    34981 ccaagcgctg tatagatgta accacgcata cccgcacggg atagctcacg gaaaaactgt
    35041 agcgcagtag gagttgcagc actttgagat acaaatgcgt agaactccag aatagccata
    35101 cagactactt ctgggtacgc ataatggact gacccatctt tgttgattgg gatataaaga
    35161 gtcggctcat tatattgctc acgctgtaaa tatgagctga taaactccat acgccctcga
    35221 gcgaaaactc cgtggcggaa gctctcttcc cactctcgag aaatatccgc gatattacta
    35281 cgatgcaccc cgcaaatcct ggccagccca ttttgcgtaa ggtaggagat cccgttctga
    35341 agaaccccca tttctatttc gttaaaaacc ccctcagtac taacacctaa gtccagtatt
    35401 tgttggggtg cgggttgctg actaccaaat tcactcattt tattgtttat ccttacattt
    35461 aaccctgtgg gttaccttcg ctgtgaatag taaaaattgc caggccaact ggtgcgacct
    35521 ctaactagca aaaatttgcg agattataat gcctcaaaac tttatccctc gcccctacca
    35581 agatctcatt atcaaccacg aaatcgacat catgcgctgc aacatctggg caggtatggg
    35641 aatgggtaaa accgtagcga cactcaccac gctggaagat cttttcatgg ctggagcaga
    35701 aacacgcccc gcgctggtcc tcgcgccgct acgcgttgca gcaagcacct ggcctgatga
    35761 agctgttaaa tgggggcatc tgcgtaatat tgaggtgcag ccgattgttg gtaacgccaa
    35821 agcgcgctct gcagcgctgg cgaacagcaa cgcaagcgtg ttcaccatca actacgataa
    35881 ccttgtctgg ctggttgagg aattgggaga acgatggccg ttcggtactg tcattccaga
    35941 tgaaagcacc cggctaaaat ccttccggct gcgaggtggt ggtaagcgcg cggcggcgct
    36001 gggcaaagtg gcgcataagt atgtccggcg ctggataaat ctcaccggta cgccagcacc
    36061 gaacggcctg gtagatttgt ggggacaagc gtggtttgtg gaccaggggc aacgtctcgg
    36121 acgcacttac ggcgcgttta cctcacgctg gttcaactcg atacagtttc cggggcagag
    36181 ctggaccaaa ctggaaccgt ttgctcactc acagggtgaa atacagcgag cgttagccga
    36241 tgtgacccta tcgctggatg cggccgactg gttcgatatc aaagacccca tccataacgt
    36301 aatccgcgtg gatatgccgc cgaaggcccg tcagcagtat cgtgaaatgg aaaaggaaat
    36361 gttcctcgag ctgaatggcg aaggcatcga agcaccgaac gccgcggcaa agacactgaa
    36421 gtgtctgcaa atcgccagtg gcgcagtata cacagacgac accggaagtt ggtcagaact
    36481 gcatgacacc aaactgcagg cgctggacag catactgacc gaagcagctg gcgcacctgt
    36541 gctggttgct tatcactgga aacacgatct tgaacgcttg cttaaagcat tccctcgcgg
    36601 tcgtcacctc gaccaagatc cacagacact gcgcgactgg aattccggaa agattcctgt
    36661 tctctttgca cacccagcca gcgcgggcca cggtctgaac atgcaggacg gcggaaacat
    36721 actggtattt ttctcacact ggtgggacct ggagcagtat cagcaaatta ttgaacgtat
    36781 cggccccacc aggcagatac aggccggaca caatcgtccg gtatttattc accacattat
    36841 tgcggccgac actatggacg aaatggtgat ggagcggcgc aactcaaaac gaacagtgca
    36901 ggacatcctg ctcgatgcca tgaaaaagag aggtatagca tgagcgagaa acccgacgat
    36961 ttactcaccc cagatgaagt atgccaaaag ttaggtatta cacagaaaac gctatgtgag
    37021 tggaatatta agcatcgtca tcgggctatc ctggcaccaa ttcgtttcag tgcaaaagta
    37081 gttcgttatg agcgccgaaa tgtcgacgct tttattcaaa agtgtcgcag ccagtattaa
    37141 cctcgccgcc gtagcaatgc aacctgcgca agtatgctcc gctcgtgagc ctcgaaagct
    37201 tcgcgcttta acgcaatctc ttcctgtaaa atctcatcag aaaagtcgta atgttctgcc
    37261 atcgggtcat ctgacttgct ggagtggtga aggcaaagga ggctgatttc ccttcggtct
    37321 gatcgggaat agcctctttc cttcattaag gcaataacat tgctcttaag gaatttacgg
    37381 cacatcgtat taaatgcacc gtctttccct ttaacagtcc catcatgttt tattcctttt
    37441 acagccccgt ccgggctgta tgttttcacc agcttatcca gtgatcgttt tgaaaatggc
    37501 tgcattggat cacgtggctg caaaaataca taatccctgt tgcactcagg aactgaatca
    37561 cgccaggctt tctgctcgtc gataatccgc cggatctcag gcgttatcgg caggcggaaa
    37621 gccttttgtg ttttcatagc ccctcgcatg ccgataaccc cttccggata aacaatttca
    37681 ccagcctcct cgtgaacgta gtcccagcgc aggttatgga cattaatcgg acgaacgcca
    37741 gtgatgatca tgaagcgaac agcattcttc tggtgtacag aggtgcaggc agcaacattg
    37801 agccagagtc gggcgattga ttcaatatcg gtaaaaagcc gtgtgggggt aggtttctgt
    37861 acgcgggagg aaacataatc atctggcaga ctggcggcaa cattgcggcc gttgcaaaga
    37921 gtaggtgcgc agaacttcca gaaccgacgg agctcggcaa acaactccag ggcgttattg
    37981 ttcgagcgag tggcgatcca ctcgtccagc acttccacca gccgattgta tgttacgtcg
    38041 ctgaacacct cacgctcgcc gaacgttgct ttaatccggt tgatacgcac cccgtaggtt
    38101 gtgaaactgt ccgggctcag cttctgccgg gcgactttgg ctttgaggtc atcccggtac
    38161 atttccagcg ctgcatgtac ggactctgcc cgcaagccac agtcagccat acctagcgct
    38221 ttttcgcgcg ccagctggat agcgagctcc ggccactcgc cgagcttttt acccttgagg
    38281 cccatctttt ttggaaactc ggcgtaaaat gtaaccttac cggctttgct gaaatcgata
    38341 cggagatagt tctctttttc gtatttggaa cggcgagcca cgccggaagc agcgaggatg
    38401 attttggcgg cagcaacaca gattttcatg tgtgcgctgg tatagggggg tttacaggcg
    38461 tcccattttt cagatgcggc taaaacatcg tcattattgg ggctatccgg attatgtgtt
    38521 acagtgcgcg gcattctcaa tccttatctg cgtaggcgca gaaaacaagc tcacacatac
    38581 aagtcttttc tacgggacaa aatgcaatgt gttgcggttt tgtgttgctg gactgagttt
    38641 atcaaggtta aatacactgg atcaacatac agtaagttaa tgacggtaaa gcatacaaac
    38701 tcgatacaac ttactgattt taaaatgatt taacggtaat ccattgaaat gtctttgcta
    38761 attactaaac gctgtattaa ttgtgatatg tgtgaacccg aatgcccgaa tgaggcgatt
    38821 tcaatgggag atcatatcta cgagattaac agcgataagt gtaccgaatg cgtagggcac
    38881 tacgagacac caacctgcca gaaggtgtgc ccgatcccca atactattgt gaaagatccg
    38941 gcgcatgtcg agacagaaga acagttgtgg gataaatttg tgctgatgca ccacgcggat
    39001 aaaatttaat attctactct ggaagtagag tattaattat attactggga agccttaacg
    39061 ccattatatt tatttaattg atgacattag cataatcatt cactaagtta atttatatag
    39121 tatctgccaa gacacttatt tatagttatt aaaggcgcgt ccgattggtt caccggacgc
    39181 accttaagta cgtttccttg tgttataaga acagaaggat cagctgtaaa acagcaatga
    39241 tgattttgat gacccgttta atcaggtatc ggcaatcagt cattcgtttt tccttaaaca
    39301 aggaatgcag ccgttcagat tagcccttac atctccccaa aactgaacgt gcgagttatt
    39361 gagggtgcat gctgcactcc acaccagagc tttgacgaca ccactcgttt caatggggga
    39421 attctgtggc atggtgtaaa gcacagcaaa atcttcaata acgaagccaa ttttaatgta
    39481 cttacgaatt ggcggtcacg ttaatctttc catcaatatt gctttcttcg taaaggctcg
    39541 agtttttatg ctaaagattg caagttgctt gtaaaagata agtacactga tccataatcg
    39601 ctgttgttga gggtgcatgc tgcacaaaat taaagttaaa aagtaaaacc cccgttcctt
    39661 accagttcgg gggttttact ttttaaagag aacggtatta ttttaacttt caataattac
    39721 cgtggcacaa gcatagtggc gttcatctgc cagcgttaca tgcatattta caacgccgag
    39781 cttttccgcc agttttaatg cctcacccca tagccgtagc cgtggtttgc cgagctcatc
    39841 attgaatact tcaaattgat taaacgccag accattgcgg atcccggtgc caaacgcttt
    39901 tgctgcggct tctttcacag caaaacgctt cgccagaaaa cgcaccggct ggtggtgcgt
    39961 tttccagatt gcccattcgt tatcgcttaa tacgcggcgt gccaggcgct caccggatcg
    40021 ggcgatcact gcttctatgc gagcgatctc tacgatatcc gtgcctaaac ctaatattgc
    40081 cattagccac gcgcttccag catcagacgc ttcatttctg ccaccgcatc tttcagtccg
    40141 gtcatcactg cacgaccaat aatggcatga ccgatattca gttcatgcat ctcagggatg
    40201 gcggcaatag ctttcacgtt gtgataggtc agaccgtgac cagcgttaac tttcagaccg
    40261 agactagcgg caaaggtcgc ggctttggcg atacgcgcca gctcttgcgc ctgttcggcg
    40321 tcagttttgg catcagcata gcaaccggtg tggatctcga taaacggtgc gccaacctct
    40381 gccgcagctt tgatctgctc ttcatcggcg tcgataaaga gagaaacctg gatcccggca
    40441 tctgccagac gtttgcaggc atcgcgcatt ttgtcacgct gccctgcgac gtccaggccg
    40501 ccttcggttg ttacttcctg acgcttttcc ggtaccagac agcaaaaatg tggcttcgtc
    40561 tcaacggcga tcgccagcat ctcttcggtc accgccatct ccagattcat gcgggtatcc
    40621 agtgtctgac gcaggatgcg cacatcacgg tcagtaatgt ggcggcgatc ttcacgtaaa
    40681 tgcacggtaa tgccgtccgc tcccgcctgc tcagcaataa acgccgcctg caccggatcc
    40741 gggtaagcag taccgcgtgc gttacgcagc gttgcaatat ggtcaatgtt gacgcctaac
    40801 agtaattcag ccatgacaat cctcatcatt cataatgtgt tttcaccgtt cgcttaggca
    40861 taaactgccg gaacagttcc ctgctcttta atggtttacc gccaagatac ggcttaagcg
    40921 ccatgcgggt aaagcgtttc gcggcgcgta gtgtgtctgc gtcaggaaat tcccgcgcgt
    40981 ttaacgcttt taactgcctt ccggtgaacg ttttattgtc gataacgacg cttgcgataa
    41041 accctttttc ttcgcgataa cgatacgtca tggtgtcatc taccggctcg ccgctacccg
    41101 cacaatgggt aaaattgacg ccatagccca gatgcccgag cagtgccagt tcaaagcggc
    41161 gcagcgcggg ttctggcgta ccagtggcac ctgcaagaga ctgaatgcag tgcaagtaat
    41221 cgaaaaagag ttcagagaag cgcgtctcgt attccagtac gcgggagaga agttcgttga
    41281 tgtacagacc gctgtaaagc gtgataccgc ttaatggcag cgccagcgag acagcttcag
    41341 cactgcgcag cgttttgact tcgccacgcc cgccgaaacg tagcaagaga ggggtgaaag
    41401 gctgtaatgc acctttcaga gtagagcgtt tagagcgtgc gcctttggca accagacgca
    41461 cgcgacccga ttcctccgtg aagacgtcca gcatcaggct ggtttcgctc cacgggcgac
    41521 tatgcaggac aaatgcgcgc tgccagcctt ccatcggagt gactcttaaa gatcgtcaac
    41581 gtaaccgaga ctgcgcagtg cgcgttcgtc gtcggcccaa ccggatttca cttttaccca
    41641 cagctcaagg tggacaggcg cttcgaacat ttcctgcatg tctttacgcg cttcaatccc
    41701 gatggttttg atcttggccc ctttgttgcc aataaccatc ttcttctgcc cttcacgctc
    41761 aacgagaatc aaaccattga tgtcataacc accgcgttcg ttagagacga aacgttcgat
    41821 ctccacggtc acggagtatg gcagttcagc gccgaggaaa cgcatcagtt tttcgcggat
    41881 gatttcagac gccataaaac gctgtgagcg atcggtgatg taatcttccg ggaagtgatg
    41941 ggtcgcttca gggaggtgct tacgcacgat tgctgcgata gtgtcgacat tcagcccggt
    42001 ttcagcagag atcggcacga tatcgaggaa gttcatctga cttgccagga actgtaagtg
    42061 cggcagcaga tcggcttttt cctgcacgtt atccactttg ttcaccgcga ggatcaccgg
    42121 cgctttgcca tcgcgcagtt tgttgagcac catttcgtcg tccggcgtcc agcgggtgcc
    42181 ttcaacgaca aaaatcacca gctcaacgtc gccaatagag ctgctcgccg ctttgttcat
    42241 caggcggtta atagcgcgtt tttcttccat atgcaggcca ggggtatcaa cgtagatcgc
    42301 ctgatacgcg ccttcagtat ggatccccac aatgcggtga cgagttgttt gcgctttgcg
    42361 ggaggtgatg gagatcttct gccccagcag tttgttcaac aatgtggatt tgccaacgtt
    42421 cggacgtccg acgatggcaa taaatccgca gtaactttta tcgatgctca ttccagctcc
    42481 agttttttca acgcctgttc ggcggcagcc tgctcagcct tacgacggct tgaacctgtg
    42541 ccaaccaccg gttcactcag gccgctgacc tggcagtgga tagtaaattc ctgatcgtgc
    42601 gcttcgccac gtacctggac taccagataa gtcggcagcg gcagatggcg accctgcaaa
    42661 tattcttgca agcgcgtttt cggatctttt tgtttatcgc ctgggctaat ttcgtccaaa
    42721 cgagtttgat accagttgag gattaatttc tcgacggttt gaatatcact gtcgaggaat
    42781 acgccaccaa ttaatgcttc gacggtgtcg gcgagaattg actcacgacg aaatccaccg
    42841 cttttaagtt cacctggccc taaacgtaag cactcgccta actcaaattc gcgcgccagt
    42901 tccgccagcg tattgccacg gaccagcgtg gcgcgcatcc ggctcatatc gccttcatcc
    42961 acacgaggga aacggtgata aagcgcattg gcgataacgt agctcagaat agagtcgcct
    43021 aaaaattcta aacgctcgtt atgtttactg ctggcactac gatgagttaa tgcctgctgc
    43081 aacagttcct gatgattaaa agtgtagccc agcttccgtt gaagccgatt aattacgatg
    43141 gggttcatgc gataccaata aataaatgcg tcaacaattc agcacacgaa acagacctga
    43201 tatacatggc tctgctaact gcttcgctgc agtttcagtt taccggtata tggggaccaa
    43261 cgctgtttcg tgtgccgtgg caacctggag gtgccaacct taaacttcgg gggaatattc
    43321 tatacacaac gacgggggat gtcgttagcc acgggagatt tatctcataa ataattcacg
    43381 ttgtcgccat aacggcgaca acgtgaacga agatgagcta ttaatggatg ccgccaatgc
    43441 gacttaagcg cacaccagtc ggccattcgc cttcttgctt atcgaagctc atccagatag
    43501 ccgttgcccg accgaccaga ttcgcttcag gcacaaaccc ccaataacgg ctgtccgcgc
    43561 tgttgtcgcg gttgtcgccc atcatgaagt attgtcccgg aggaacaatc caggttgcca
    43621 gttgttgccc tggctgctgg taatacatcc ccacctgatc ctgcgcaatc ggcactgtca
    43681 gaattcggtg cgtcacatca cccagtgtct ctttacgctc ggaaagacga attccatttt
    43741 ctttggtttc gtttttcggc acttcaaaga atccgctggt cgcttcccca ccattacggc
    43801 gtgagaaggt ctgaacgaaa tcgctcggtt ccacgtttga gtaggtgacc ggcagcgcgt
    43861 tttcacacgc ctggccggaa ctgcatcccg gttgaatcgt cagctctttc gagaccggat
    43921 cataagtaac tttatcgccc ggtaaaccca ccgcgcgctt gatgtaatca agctttggat
    43981 cttccggata tttaaagacc acgatatctc cgcgtttcgg atgaccggtt tcgatcagcg
    44041 ttttctggta gataggatct ttaatgccat aagcaaactt ttctaccaga ataaaatcac
    44101 cgattaacag agtcggcatc atcgaacctg acgggatctg gaacggttca taaataaacg
    44161 aacgcacaat caatacgata gccagtaccg gaaaaacaga agcaccggtt tccagccagc
    44221 caggcttcgg cgcaaccttt ttcaacgttg ctttatccag tgagtcaccg gcagccgcct
    44281 gcgccgctgc ctgacgttcc cgccgtttag gtgcgaaaaa gaatttatcc acgcaccata
    44341 aaatgcccgt caccagtgtg gcaatcacca gaatcagggc aaacatattc gccatgccaa
    44401 ctcctaaggg ttatttgttg tctttgccga cgtgcagaat ggcgaggaac gcttcctgcg
    44461 gcagctcgac gttaccgatc tgcttcatgc gtttcttacc ttctttctgc ttctgcagca
    44521 gctttttctt acggctgata tcgccgccat aacatttagc cagtacgttt ttacgcagct
    44581 gtttcacggt ggatcgcgca ataatgtgcg taccaatcgc tgcctgaatg gcgatatcaa
    44641 actgctggcg tgggatcaga tctttcatct tctccaccaa ctcgcgaccg cggttttgcg
    44701 aattatcacg gtgggtgatc agcgccaacg catcaacacg ttcaccgttg attaatacgt
    44761 ctacacgtac catgtcggac gcctggaagc gtttgaagtt gtaatccaga gacgcataac
    44821 cacgcgaggt agatttcagg cgatcgaaga agtcgagcac cacttccgcc atcgggatct
    44881 cgtacgtcag cgccacctga ttaccgtggt aaaccatatt ggtctgcacg ccgcgttttt
    44941 ctacgcacag cgtaataacg ttgccgagat atgcctgcgg cagcagcatg tgacattcgg
    45001 caatcggctc gcgcagttcg tagatgttat ttaccgctgg cagcttggat ggactgtcga
    45061 cgtaaataac ttctcttgac gtggtttcaa cttcatacac tacggtcggc gcagtggtga
    45121 tcagatccag atcgtattca cgttccagac gttcctggat gatctccatg tgcagcaggc
    45181 cgaggaagcc gcagcggaaa ccaaagccca gcgcgctgga gctttccggc tcatagaaca
    45241 gtgaagcatc gttcaggctg agtttaccca gcgcgtcacg gaaggcttca tagtcgtcgg
    45301 aacttaccgg gaacagaccg gcgtatacct gcggtttgac tttcttaaag ccaggcagcg
    45361 ccttttctgc cggattacgc gccagcgtta aggtatcgcc gactggagcg ccgtggatat
    45421 ctttaatcgc acataccagc cagcctactt cgccacattt cagttcagtg cggtcaacct
    45481 gtttcggcgt gaagatgccc agacggtcgg cgttataggt ctgcccggta ctcatgactt
    45541 tcactttgtc gcccttacgc agggtgccgt ttttaatacg gataagtgaa acaacgccca
    45601 ggtagttgtc gaaccatgag tcgataatta gtgcctgcaa cgggccttcc ggatcgcctt
    45661 ccggcggcgg aatgtcgcgc accagacgtt cgagaacgtc ctgcacgcca acgccggttt
    45721 tcgctgaaca gcgcaccgcg tcagtggcgt cgatgccgac gatatcttca atttcttccg
    45781 ccacgcgttc aggatcggct gccggcaggt caatcttgtt cagtactggc accacttcga
    45841 gatccatttc catggcggtg tagcagtttg ccagggtttg cgcttccacg ccctgcccgg
    45901 cgtcgaccac cagcaatgca ccttcacagg cagccagcga acgggaaact tcataggaga
    45961 agtctacgtg gcccggggtg tcgataaagt taagctgata ggtttcgccg tcagacgctt
    46021 tgtagtccag cgtcacgctt tgcgctttga tggtaatgcc acgctcacgc tcaagatcca
    46081 tggaatcgag aacctgcgcc tccatttcac ggtcagacag gccaccgcag atctggataa
    46141 tacggtcaga cagcgtcgat ttaccgtggt caatgtgagc tatgatcgaa aagttacgta
    46201 tattcttcat aaagtatgat tattgtgcct taatgcccgg ttaaccaggc ttttagaagt
    46261 cgctgttctg agcttaacgt ctgtattaat agaaacgccg cattctacac tacaacattg
    46321 aggcgaggaa atgttcatac cgtatggatt gtggtatctg gaaacgtcct cgcatttgtt
    46381 atgcaaaatg caacaaagcc agtgaaatca ctggctcgcg tcttccgaag atgtttcaaa
    46441 tcgcacaagg ccaggcggca atgccacgct taagatgatc ggttgccatt ctgcccgggc
    46501 agcaaactta cgcgagtagc cgcgcgcaat caggaacccg ccaataccac cgaggatcgc
    46561 accacataat gctgcgacgt cagaagcaaa gagtagctga aatagcgaag cgataaggaa
    46621 taatcccacc agcggcgaca tataaaccag taatgcggag ctaagcaggc tgccttcggc
    46681 gatccccaat tccacttttt gccccggcac taacggttca tcacagggta cgacaatggt
    46741 atgcgtggtt tgcgggccaa gtttattcaa cacgcggcta ccgcaaccgg cgcgtgaagc
    46801 gcagctgctg catgaagctt taacatcaca actgaccagc gcctgcccgt tttgccagga
    46861 gacgacggta gcccactctt tgatcattgc gctgccccga acttaatatt ctcggcaatg
    46921 cgtttcgccg tttgcggcgg cagttcaccg acaatggtga tttcggcgtt atcacgtacg
    46981 cttgtactga cggttctgcg tccggtgcgc aacatctgat cggtgctcga tggcgtagcg
    47041 cggttaacgt ttaccgagaa gctgaataat ccgtcggaat agagacgtga ttcgataggc
    47101 atgttgtcca tcgtcggtag cggacgtcga ctactggaaa cttcgctaaa accctgtggc
    47161 aaccaggttg gcgtccagct gaatttagct ttttcaccta caggaacaga aagcaacggc
    47221 ggcaaatttg ccttcgccag cgtctgcata ctgctactga tatcctgatt gacgttaaaa
    47281 gcaatcacgc gaaattgttc cagcgtttca ccatcgcgat caaggagatc aaccctcatc
    47341 ggtaatttcg attcgatgtc catccacacg atgtagctgt agcgtgtacc atctcgggca
    47401 accacgcgaa tgacttcgca aagacgatca gcaatacgcg tgcgcccgac ggagataaag
    47461 tcgtagtaag gagaaaggcg tttgaaatcg gtatagatga gcgatggcag agaatcaaca
    47521 atgtaatcgc cattaagcgt gaacggttca agtcccggtt caaaatagct gatttcattg
    47581 ccgcgctgta ccacttcccg gcgcgggcca tccatttgca acaattgtgc aagaggacgg
    47641 ttatcgaggc gtgcatgtcg ataacgcaga gactcaacac cctgtttatt gatgctgatg
    47701 aatgacagct cgtaattcag tgactgactg gccaggttca tctgctgtaa taacgccccg
    47761 gacgcgggag tggccgaggc gttagcagag aataacaggc tacctgtcac taatgacatg
    47821 gcaaaccaaa gttgcttcat tactgcgatt gcgttcctaa agtttgaatt cctggcacct
    47881 gtacagcggc ttgctgggtt tgcgcctgct caaactgaag ctgttcagag tggagtcggc
    47941 gttgcagttc gtaatcctgc aacattgcat taatgcgacg acgctgctcc tgtacctgct
    48001 gctgttgacc attgtttgcg gtcgcttcag aaggtactcc caggcttacc gggctggctt
    48061 tacccatcat cggcagtgta ttaaataccg gcgtttcggg ctgctgggac gtttcagatt
    48121 gtccattata gtgctggacg ccaacgataa ctgcaagcga tacgcatgct gctacgccca
    48181 tttgggtaag ctgtgccgcc cacggacgta ctttctgcca gaatggcatt ttctgccatt
    48241 gatgcggcgc aggctgggct tccgggatca atgtcgccgg ttgacgtact ggctcttctt
    48301 caatggcggc catcacgcgt gaagagatat cgaaatggag cacctcggga gtatcacccc
    48361 gcattgagtc acggattaag tgatagcttt cccaggtttt ctgcatttct gggttatgag
    48421 ccagttcgtt aagcagctca ctatccagcg tttcgccatc cattaaagcg gaaagttgtt
    48481 ctttctgcat gcctaatacc cttatccagt atcccgctat cgtcaacgcc tgataagcgg
    48541 ttgaactttg ttatcaatag cttccctcgc tcggaagata cgtgaacgca ccgtacctac
    48601 cggacaatcc atgatagcgg ctatctcttc atagctcagg ccatccagct cccgcaaggt
    48661 tattgccatg cgcaaatctt ccgggaggga ctcaatagtt cggaaaacta tctgtctcag
    48721 ttcttctgac aacattaagt tctcagggtt cgaaatttct ttcaacgcgc cgccactttc
    48781 gaagttttca gcttcaatgg catccacatc actggaaggt ggacgacgcc cctgagcaac
    48841 caggtaattt ttcgctgtat ttacagcaat ccgatacagc catgtataaa aagcgctatc
    48901 tccccggaac gaatccagcg cacgataggc tttaataaaa gcttcttgta ccacatcggg
    48961 aacatcaccc gacggcacat agcgggaaac cagactcgcc actttatgct gatagcgcac
    49021 taccagtagg ttaaaggctt tctgatctcc cttctggacc cgttcaacca ggacctggtc
    49081 cgttaactgc tcgctcatcc gaggtaaagt ctccccaaac caaatttcca cgcgctatcg
    49141 aaacgccact ccattagctg caatttgagc aagcaaaggg ttagagtgtc tcgtttttgt
    49201 aaagttccgt aacgcatctg tttttgtttg tcatgctgta gacggatcat tatctatcat
    49261 tataagtcta cagaatctga acatcgcatt atctgtgtag aaatgcccat ttaactgcct
    49321 gaagagtaac ccaacggcct ttttatttca ccacctaatc ctccaccagc cagtaacttc
    49381 tctttttctc gccgccctgc gtcagcgtgt ttagccactg taacaaatat taaaatagca
    49441 ggtgtttatt cgcacaacat gatgctatgc tgaccaaacg gtgtttagta aattaaacaa
    49501 agaaaatgaa tactctccca gaacattcat gtgacgtgtt gattatcggt agcggcgcag
    49561 ccggactttc actggcgcta cgcctggctg accagcatca ggtcatcgtt ctaagtaaag
    49621 gcccggtaac ggaaggttca acattttatg cccagggcgg tattgccgcc gtgtttgatg
    49681 aaactgacag cattgactcg catgtggaag acacattgat tgccggggct ggtatttgcg
    49741 atcgccatgc agttgaattt gtcgccagca atgcacgatc ctgtgtgcaa tggttaattg
    49801 accaaggggt tttgtttgat acccacgttc aaccgaatgg cgaagaaagc taccatctga
    49861 cccgtgaagg tggacatagt caccgtcgta ttcttcatgc cgccgacgcc accggtagag
    49921 aagtacaatc cacgctggtg agcaaggcgc agaaccatcc gaatattcgt gtgctggagc
    49981 gcagcaacgc agttgatctg attgtttctg acaaaattgg cctcccgggc acgcgacggg
    50041 ttgttggcgc gtgggtatgg aaccgaaata aagaaacggt ggaaacctgc cacgcaaaag
    50101 cagtggtact ggcaaccggc ggtgcgtcga aggtttatca gtacaccacc aatccggata
    50161 tttcttctgg cgatggcatt gctatggcgt ggcgcgcagg ctgtcgggtt gccaatctcg
    50221 aatttaatca gttccaccct accgcactgt atcacccaca ggcacgcaat ttcctgttaa
    50281 cggaagcact gcgcggcgaa ggcgcttatc tcaagcgccc ggatggcacg cgttttatgc
    50341 ccgattttga tgagcgcggc gaactggccc cgcgcgatat tgtcgcccgc gccattgacc
    50401 atgaaatgaa acgcctcggc gcagattgta tgttcctcga catcagccat aagcccgccg
    50461 attttattcg ccagcatttc ccgatgattt atgaaaaatt gctcgggctg gggattgatc
    50521 tcacacaaga accggtaccg attgtgcctg ctgcacatta tacctgcggt ggtgtaatgg
    50581 ttgatgatca tgggcgtacg gacgtcgagg gcttgtatgc cattggcgag gtgagttata
    50641 ccggcttaca cggcgctaac cgcatggcct cgaattcatt gctggagtgt ctggtctatg
    50701 gctggtcggc ggcagaagat atcaccagac gtatgcctga tgcccacggc gtcagtacgt
    50761 taccgccgtg ggatgaaagc cgcgttgaga accctgacga acgggtagta attcagcata
    50821 actggcacga gctacggctg tttatgtggg attacgttgg cattgtgcgc acaacgaagc
    50881 gcctggaacg cgccctgcgg cggataacca tgctccaaca agaaatagac gaatattacg
    50941 cccatttccg cgtctcaaat aatttgctgg agctgcgtaa tctggtacag gttgccgagt
    51001 tgattgttcg ctgcgcgatg atgcgcaaag aaagccgggg gctgcatttt acgctggatt
    51061 acccggaact gctcacgcat tccggtccat cgatcctttc ccccggcaat cattacataa
    51121 acagataaaa agcctgggtc agcgccgtat acgcttcgga atagttctgg tctggcccac
    51181 gaatgactaa gcgatcgcta aagcattctc ccgcctgcgg ggagaatgcc agcagcaccc
    51241 gatgcggcag tcgcgcttcg ttttccgcca catccgtccg caaacgtaaa tgccagccca
    51301 tgcttaatgc cagttcagta aaaccattac caatctgctc tggcagcacc acgcagaaaa
    51361 atccctcttc ggtaatgcac tccgccgcac aggtcagcag cgatgggtga tcaagcgtag
    51421 tggtatagcg agcctgttcc cgttgaggtg tcgcgcactc tactccctgc tgatagtaag
    51481 gtgggttact gatgattaaa tcgaagcgta ctgtctgctg tgtgatccac tgctgaatat
    51541 ccgccgtatg gacgttaatc cgctctgccc acggggactg gttgatattt tcctgcgcct
    51601 gcgcggcagc ttcactttcc agctcaacgg catcaattat cacgctgtca ctggttcgct
    51661 gcgccagcat cagtgccagc aacccgctac ccgcgccgat atcaaggcaa cgtttcaccc
    51721 cagccaccgg tgcccatgcg cccagcaaaa tgccatccgt tcccactttc atcgcacagc
    51781 gatcgtgagc aacaaaaaac tgtttaaaag taaatccatt acgacgaagc acggatgtag
    51841 actgtgacat gaaaataaaa ccttgcagga aaaacggcga tagcaccggg tgagaacaat
    51901 acccgagaag cgatatccat acaaacagat gaagattgca gccgtaacgt ctataatcag
    51961 cgccccacac agaggtagaa catgactgta acgacttttt ccgaacttga actcgacgaa
    52021 agcctgctgg aagccctcca ggataaaggt ttcactcgcc cgaccgccat tcaggctgcc
    52081 gccattccgc ctgcgctcga tggccgtgat gtactcggtt ctgcgccgac aggcaccggt
    52141 aaaacggcgg cgtatctgct gccagcgttg cagcacctgc tcgatttccc gcgtaagaaa
    52201 tccggtccgc cgcgtatttt gatcctcacc ccaactcgcg agctggcgat gcaggtggcc
    52261 gatcatgccc gcgaactggc gaaacatacg catctggata tcgccaccat caccggcggc
    52321 gtagcctata tgaaccacgc ggaagtgttc agcgaaaatc aggacatcgt ggtcgccacg
    52381 accggacgtc tgctgcaata cataaaagaa gagaacttcg attgccgcgc ggttgaaacg
    52441 ctgatcctcg acgaagcaga ccgtatgctg gatatgggct tcgctcagga tatcgaacat
    52501 attgctggcg aaacgcgctg gcgtaaacag accctgctct tttcggcaac gctggaaggc
    52561 gatgcgattc aggactttgc cgagcgtctg ctggaagatc cggtggaggt ttctgccaat
    52621 ccgtccaccc gtgagcgcaa aaaaattcat cagtggtatt accgcgccga tgacctggaa
    52681 cataaaaccg cattgctggt gcatctgtta aaacagccgg aagcgacccg ctcaattgtg
    52741 tttgtgcgta agcgtgaacg tgtgcatgag ctggcaaact ggctgcgcga agcgggcatc
    52801 aacaactgct atctcgaagg tgagatggta caaggcaagc gtaacgaagc gatcaagcgt
    52861 ttgaccgaag gtcgcgtaaa cgtactggtt gcaaccgatg ttgccgcgcg cggtatcgac
    52921 attcctgacg tcagccacgt ctttaacttc gatatgccgc gcagtggcga tacttatttg
    52981 caccgtatcg gacgtaccgc gcgcgccggt cgtaaaggca ccgcaatttc gctggtggaa
    53041 gcccatgacc atttgctgct gggcaaggtt ggccgttaca ttgaagagcc gattaaagct
    53101 cgcgttattg atgagttacg cccgaaaacg cgtgcgccaa gcgagaagca gaccggcaag
    53161 ccatcgaaga aagtactggc aaaacgcgcc gagaagaaaa aagctaaaga gaaagagaaa
    53221 ccgcgtgtga aaaaacgcca tcgcgacacc aaaaatattg gtaagcgccg taaaccaagc
    53281 ggaacgggcg tgccaccgca aacgacagaa gagtaatctc aatgccgggt ttaagcctgg
    53341 tattaaaagt gctggcaaac gcaaaa
//
LOCUS       DAZUDJ010000030        51127 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.030, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000030 DAZUDJ010000000
VERSION     DAZUDJ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 51127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51127
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.030"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(377..853)
                     /gene="ybhB"
                     /locus_tag="ACHY1N_002390"
     CDS             complement(377..853)
                     /gene="ybhB"
                     /locus_tag="ACHY1N_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HFS4044690.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDEVPAGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTG
                     YDGAAPPKGETHRYIFTVHALDVERIDVDEGASGAMVGFNVHFHSLASASITAMFS"
     gene            complement(912..2201)
                     /gene="bioA"
                     /locus_tag="ACHY1N_002391"
     CDS             complement(912..2201)
                     /gene="bioA"
                     /locus_tag="ACHY1N_002391"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004015 -
                     adenosylmethionine-8-amino-7-oxononanoate transaminase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HFS4044691.1"
                     /translation="MTTDDIAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGRR
                     LVDGMSSWWAAIHGYNHPQLNAAMKTQIDAMSHVMFGGITHAPAIELCRKLVAMTPQP
                     LECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNS
                     MHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAG
                     GMRMYHPEWLKRIRKMCDREGILLIADEIATGFGRTGKLFACEYAEIAPDILCLGKAL
                     TGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAIIESGEWQQ
                     QVAAIEVQLREQLAPARDAEMVADVRVLGAIGVVETTRPVNMAALQKFFVEQGVWIRP
                     FGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ"
     gene            2288..3328
                     /gene="bioB"
                     /locus_tag="ACHY1N_002392"
     CDS             2288..3328
                     /gene="bioB"
                     /locus_tag="ACHY1N_002392"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HFS4044692.1"
                     /translation="MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAW
                     KNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMT
                     PDTDEYYNAAAL"
     gene            3325..4479
                     /gene="bioF"
                     /locus_tag="ACHY1N_002393"
     CDS             3325..4479
                     /gene="bioF"
                     /locus_tag="ACHY1N_002393"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008710 - 8-amino-7-oxononanoate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HFS4044693.1"
                     /translation="MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNF
                     SSNDYLGLSHHPQIIRAWQQGAEQFGVGSGGSGHVSGYSVAHQALEEELAEWLGYSRA
                     LLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPSQLRRFAHNDVTHLAR
                     LLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRG
                     SCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQAL
                     RASLAVIRSEEGDARREKLAALITRFRAGVQGSPFTLADSRSAIQPLIVGDNSRALQL
                     AEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEMLHGNG"
     gene            4466..5221
                     /gene="bioC"
                     /locus_tag="ACHY1N_002394"
     CDS             4466..5221
                     /gene="bioC"
                     /locus_tag="ACHY1N_002394"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010340 - carboxyl-O-methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HFS4044694.1"
                     /translation="MATVNKQAIAAAFGRAAAHYEQHADLQRQSADVLLAMLPQRKYT
                     HVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATA
                     TFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQAWQAVDERP
                     HANRFLPPGAIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRIL
                     TRSQLQRLQLAWPQKQGRYPLTYHLFLGVIARE"
     gene            5214..5891
                     /gene="bioD"
                     /locus_tag="ACHY1N_002395"
     CDS             5214..5891
                     /gene="bioD"
                     /locus_tag="ACHY1N_002395"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706656.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="HFS4044695.1"
                     /translation="MSKRYFVTGTDTEVGKTVASCALLQAAKAVGYRTAGYKPVASGS
                     EKTPEGLRNSDALALQHNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAG
                     LRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTA
                     QAIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGK
                     YINLALL"
     gene            6470..8491
                     /gene="uvrB"
                     /locus_tag="ACHY1N_002396"
     CDS             6470..8491
                     /gene="uvrB"
                     /locus_tag="ACHY1N_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFS4044696.1"
                     /translation="MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLE
                     NNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVP
                     MDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
     gene            complement(8683..9591)
                     /gene="yvcK"
                     /locus_tag="ACHY1N_002397"
     CDS             complement(8683..9591)
                     /gene="yvcK"
                     /locus_tag="ACHY1N_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFS4044697.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTP
                     IQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMV
                     YIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVL
                     EASDIPYRHDRQLLHNALEKALQALG"
     regulatory      9856..10000
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            9988..10977
                     /gene="moaA"
                     /locus_tag="ACHY1N_002398"
     CDS             9988..10977
                     /gene="moaA"
                     /locus_tag="ACHY1N_002398"
                     /EC_number="4.1.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HFS4044698.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNK
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNG
                     YRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVK
                     VNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELL
                     RRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLF
                     GEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG"
     gene            10999..11511
                     /gene="moaB"
                     /locus_tag="ACHY1N_002399"
     CDS             10999..11511
                     /gene="moaB"
                     /locus_tag="ACHY1N_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HFS4044699.1"
                     /translation="MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHV
                     VDKAIVKENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            11514..11999
                     /gene="moaC"
                     /locus_tag="ACHY1N_002400"
     CDS             11514..11999
                     /gene="moaC"
                     /locus_tag="ACHY1N_002400"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061799 - cyclic pyranopterin
                     monophosphate synthase activity [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HFS4044700.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     IDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEAD
                     D"
     gene            11992..12237
                     /gene="moaD"
                     /locus_tag="ACHY1N_002401"
     CDS             11992..12237
                     /gene="moaD"
                     /locus_tag="ACHY1N_002401"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HFS4044701.1"
                     /translation="MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHMAAQSDRWAL
                     ALEDGKLLAAVNQTLVSFDHPLTDGDEVAFFPPVTGG"
     gene            12239..12691
                     /gene="moaE"
                     /locus_tag="ACHY1N_002402"
     CDS             12239..12691
                     /gene="moaE"
                     /locus_tag="ACHY1N_002402"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HFS4044702.1"
                     /translation="MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLG
                     DSVKALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSA
                     HRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW"
     gene            12828..13532
                     /gene="ybhL"
                     /locus_tag="ACHY1N_002403"
     CDS             12828..13532
                     /gene="ybhL"
                     /locus_tag="ACHY1N_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFS4044703.1"
                     /translation="MDRFPRSDSIVQPRAGLQTYMAQVYGWMTVGLLLTAFVAWYAAN
                     SAAVMELLFTNRVFLIGLIIAQLALVIVLSAMIQKLSAGVTTMLFMLYSALTGLTLSS
                     IFIVYTAASIASTFVVTAGMFGAMSLYGYTTKRDLSGFGNMLFMALIGIVLASLVNFW
                     LKSEALMWAVTYIGVIVFVGLTAYDTQKLKNMGEQIDTRDTSNLRKYSILGALTLYLD
                     FINLFLMLLRIFGNRR"
     gene            13677..14381
                     /locus_tag="ACHY1N_002404"
     CDS             13677..14381
                     /locus_tag="ACHY1N_002404"
                     /inference="COORDINATES: protein motif:HMM:NF013214.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HFS4044704.1"
                     /translation="MNRQSTATQLQQKSASLSKMLLLIWWLTAAGVWATAGCAWIFQH
                     LHWVTSQKSPGAFVFALAALIIGGLWLNNALKRLNVSGACLVYLLIILLVGFLFASLY
                     TFSSIATVMGITGGMFAAMALICSCSNRVIPPVRQLYSYIFCGLSIAFVVNLILTSSF
                     SVWLASILTVFIWGITAACEATTLEDLIRVADTSEISGSLRCIVPGAITLYFSILSVL
                     FRITVTVLEFINGLVW"
     gene            14451..15164
                     /locus_tag="ACHY1N_002405"
     CDS             14451..15164
                     /locus_tag="ACHY1N_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003570877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFS4044705.1"
                     /translation="MNSRSANNITNDFQHEARILNSIWLITALGLVTTAGLAWVAKYL
                     EITATKYDSPQMYVAIGLLLLCMYGLSKDINKINAVIAGVIYLFLLSLVAIVVASLAP
                     VPAIIVVFSTAGAMFLISMLAGLLFNVDPGSHRFIIMMTLTGLALVIIMNAALMSERP
                     VWVISCLMIVLWSGIISHGRNKLLELAGKCHSEELWSPVRCAVTGALTLYYYFIGFFG
                     ILAAIAITLVWQRHTRFFH"
     gene            complement(15200..16156)
                     /gene="ybhN"
                     /locus_tag="ACHY1N_002406"
     CDS             complement(15200..16156)
                     /gene="ybhN"
                     /locus_tag="ACHY1N_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase
                     domain-containing protein"
                     /protein_id="HFS4044706.1"
                     /translation="MSKSHPRWRLAKKILTWLFFIAVIVLLVVYAKKVDWEEVWKVIR
                     DYNRVALLSAVGLVVVSYLIYGCYDLLARFYCGHKLAKRQVMLVSFICYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLAGIIFTAGVVELPDHWYVD
                     QTTLRILGIGLLMIIAVYLWFCAFAKHRHMTIKGQKLVLPSWKFALAQMLISSVNWMV
                     MGAIIWLLLGQSVNYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFIALLAGEHTSKGS
                     IIAALLAYRVLYYFIPLLLALICYLLLESQAKKLRAKNEAAM"
     gene            complement(16156..17397)
                     /gene="clsB"
                     /locus_tag="ACHY1N_002407"
     CDS             complement(16156..17397)
                     /gene="clsB"
                     /locus_tag="ACHY1N_002407"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HFS4044707.1"
                     /translation="MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFE
                     DDVGKQLHAALLAAAQRGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLF
                     GMRTNVFRRMHRKIVVIDARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDIL
                     QFELENLPGQSAARRWWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQ
                     ARREVIIANAYFFPGYRFLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVK
                     GGVQVFEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRD
                     NLNGIIAADCQQVDETMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPRLAQVDP
                     PAQPTMETQDRVETENTGVKP"
     gene            complement(17394..18155)
                     /gene="ybhP"
                     /locus_tag="ACHY1N_002408"
     CDS             complement(17394..18155)
                     /gene="ybhP"
                     /locus_tag="ACHY1N_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFS4044708.1"
                     /translation="MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADI
                     VCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEW
                     VNELPDGEPVLVAGDFNDWRQKANHPLKVQAGLDEIFTRAHGRPARTFPVQFPLLRLD
                     RIYVKNASASAPTALPLRTWRHLSDHAPLSAEIHL"
     gene            18288..18698
                     /gene="ybhQ"
                     /locus_tag="ACHY1N_002409"
     CDS             18288..18698
                     /gene="ybhQ"
                     /locus_tag="ACHY1N_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhQ family protein"
                     /protein_id="HFS4044709.1"
                     /translation="MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGL
                     CALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTWYFGAALIVLWLLSRVLENNFLL
                     AIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR"
     gene            complement(18660..19766)
                     /gene="ybhR"
                     /locus_tag="ACHY1N_002410"
     CDS             complement(18660..19766)
                     /gene="ybhR"
                     /locus_tag="ACHY1N_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4044710.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFP
                     ADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISS
                     LCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM"
     gene            complement(19777..20910)
                     /gene="ybhS"
                     /locus_tag="ACHY1N_002411"
     CDS             complement(19777..20910)
                     /gene="ybhS"
                     /locus_tag="ACHY1N_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4044711.1"
                     /translation="MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFG
                     YGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRG
                     LVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
                     FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLS
                     TEITRTELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTL
                     GMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFV
                     STLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            complement(20903..22639)
                     /gene="ybhF"
                     /locus_tag="ACHY1N_002412"
     CDS             complement(20903..22639)
                     /gene="ybhF"
                     /locus_tag="ACHY1N_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFS4044712.1"
                     /translation="MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGA
                     GKTTLMRMLAGLLKPDSGNATVIGFDPIKNDGALHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GEPKALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPD
                     DIRHAEGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKE
                     LTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMD
                     LKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGL
                     KSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQ
                     LIHDWDKEHSNE"
     gene            complement(22632..23627)
                     /gene="hlyD"
                     /locus_tag="ACHY1N_002413"
     CDS             complement(22632..23627)
                     /gene="hlyD"
                     /locus_tag="ACHY1N_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308900.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HFS4044713.1"
                     /translation="MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTV
                     NLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLA
                     GYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
                     LKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRA
                     VEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQI
                     GFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGNEAGHE"
     gene            complement(23630..24301)
                     /gene="cecR"
                     /locus_tag="ACHY1N_002414"
     CDS             complement(23630..24301)
                     /gene="cecR"
                     /locus_tag="ACHY1N_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415317.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CecR"
                     /protein_id="HFS4044714.1"
                     /translation="MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQN
                     IAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRA
                     CRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
                     NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGL
                     SQRSL"
     gene            24530..25894
                     /gene="rhlE"
                     /locus_tag="ACHY1N_002415"
     CDS             24530..25894
                     /gene="rhlE"
                     /locus_tag="ACHY1N_002415"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HFS4044715.1"
                     /translation="MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITRQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEADR
                     MLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASD
                     QVTQHVHFVDKKRKRELLSHMIGKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIPGYEPDPSIKAEPIQNGRQ
                     QRGGGGRGQGGGRGQQQPRRGEGGAKSASAKPAEKPSRRLGDAKPAGEQQRRRRPRKP
                     TAAQ"
     gene            complement(26126..26608)
                     /gene="ybiA"
                     /locus_tag="ACHY1N_002416"
     CDS             complement(26126..26608)
                     /gene="ybiA"
                     /locus_tag="ACHY1N_002416"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-glycosidase YbiA"
                     /protein_id="HFS4044716.1"
                     /translation="MPVRAQRIQHVMQDTIINFYSTSDDYGDFSNFAAWPIKVDGKTW
                     PTSEHYFQAQKFLDEKYREEIRRVSSPMVAARMGRDRSKPLRKNWESVKEQVMRKALR
                     AKFEQHPELRALLLATAPAKLVEHTENDAYWGDGGNGKGKNRLGYLLMELREQLAIEK
                     "
     gene            26728..28878
                     /gene="dinG"
                     /locus_tag="ACHY1N_002417"
     CDS             26728..28878
                     /gene="dinG"
                     /locus_tag="ACHY1N_002417"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HFS4044717.1"
                     /translation="MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAG
                     EEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKK
                     IIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLK
                     GDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAE
                     VVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQL
                     DLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEH
                     RFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRA
                     LGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWR
                     SIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVE
                     PSIDNEEQHIAEMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGD
                     QPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVI
                     TEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKR
                     LLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR"
     gene            28906..29868
                     /gene="ybiB"
                     /locus_tag="ACHY1N_002418"
     CDS             28906..29868
                     /gene="ybiB"
                     /locus_tag="ACHY1N_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
                     /protein_id="HFS4044718.1"
                     /translation="MDYRKIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGG
                     VLIALRIKGEGEAEMLGFYEAMQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLA
                     ILLHKLGFPVVVHGVSEDPTRVLTETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGA
                     FCPPLEKQLAMRWRMGVRNSAHTLAKLATPFAEGEALRLSSVSHPEYIGRVAKFFSDI
                     GGRALLMHGTEGEVYANPQRCPQINLIDREGMRVLYEKQDPAGSELLPQAKDPETTAQ
                     WIERCLAGSEPIPESLKIQMACCLVATGEAATISDGLARVNQAF"
     gene            30009..31094
                     /gene="hcxB"
                     /locus_tag="ACHY1N_002419"
     CDS             30009..31094
                     /gene="hcxB"
                     /locus_tag="ACHY1N_002419"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcXB"
                     /protein_id="HFS4044719.1"
                     /translation="MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAG
                     HDSHGIGMIPSYVRSWSQGHLQINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGI
                     EKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRF
                     GTNPFCVVFPRKDNFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPA
                     VMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTII
                     INPELFGAPDCSAQTEAFAEWVKASPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGS
                     WQAICDAARQIGMSEETLQAFCQQLAS"
     gene            31161..31220
                     /gene="ybiE"
                     /locus_tag="ACHY1N_002420"
     CDS             31161..31220
                     /gene="ybiE"
                     /locus_tag="ACHY1N_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YbiE"
                     /protein_id="HFS4044720.1"
                     /translation="MRLSANRQGNTCAGRSVNA"
     gene            complement(31323..31583)
                     /gene="ybiJ"
                     /locus_tag="ACHY1N_002421"
     CDS             complement(31323..31583)
                     /gene="ybiJ"
                     /locus_tag="ACHY1N_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 family protein YbiJ"
                     /protein_id="HFS4044721.1"
                     /translation="MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADG
                     ASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSGTAVIYK"
     gene            complement(31848..32114)
                     /gene="ybiI"
                     /locus_tag="ACHY1N_002422"
     CDS             complement(31848..32114)
                     /gene="ybiI"
                     /locus_tag="ACHY1N_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-type zinc finger protein YbiI"
                     /protein_id="HFS4044722.1"
                     /translation="MASGWANDDAVNEQINSTIEDAIARARGEIPRGESLDECEECGA
                     PIPQARREAIPGVRLCIHCQQEKDLQKPAYTGYNRRGSKDSQLR"
     gene            complement(32188..32865)
                     /gene="ybiX"
                     /locus_tag="ACHY1N_002423"
     CDS             complement(32188..32865)
                     /gene="ybiX"
                     /locus_tag="ACHY1N_002423"
                     /EC_number="1.14.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKHD-type hydroxylase YbiX"
                     /protein_id="HFS4044723.1"
                     /translation="MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQ
                     QVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVR
                     SHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCV
                     TPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGENEEILSLLNLYHNL
                     LREWSEI"
     gene            complement(32907..35189)
                     /gene="fiu"
                     /locus_tag="ACHY1N_002424"
     CDS             complement(32907..35189)
                     /gene="fiu"
                     /locus_tag="ACHY1N_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015344 - siderophore uptake transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor Fiu"
                     /protein_id="HFS4044724.1"
                     /translation="MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTL
                     VVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVG
                     AFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
                     YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGE
                     KTHDAGRDKVKNERYGVAPSIAFGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSA
                     PSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVK
                     QDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGH
                     DVSTGVEFTRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYA
                     FDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPAGVAKGSPVTTVDTAK
                     SGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKA
                     NTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNI
                     TPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGAR
                     YIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASINKS
                     GYRYHPGEPRTFLLTANMHF"
     gene            complement(35453..35713)
                     /gene="mcbA"
                     /locus_tag="ACHY1N_002425"
     CDS             complement(35453..35713)
                     /gene="mcbA"
                     /locus_tag="ACHY1N_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415327.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 family periplasmic protein McbA"
                     /protein_id="HFS4044725.1"
                     /translation="MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATG
                     ASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTATIYK"
     gene            35989..36915
                     /gene="rlmF"
                     /locus_tag="ACHY1N_002426"
     CDS             35989..36915
                     /gene="rlmF"
                     /locus_tag="ACHY1N_002426"
                     /EC_number="2.1.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415328.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008988 - rRNA
                     (adenine-N6-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
                     /protein_id="HFS4044726.1"
                     /translation="MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSV
                     DFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIP
                     ANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLR
                     RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGG
                     QQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVV
                     KKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR"
     gene            complement(36912..39137)
                     /gene="ybiO"
                     /locus_tag="ACHY1N_002427"
     CDS             complement(36912..39137)
                     /gene="ybiO"
                     /locus_tag="ACHY1N_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HFS4044727.1"
                     /translation="MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQ
                     KKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEV
                     SRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL
                     PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRT
                     IAFQQSLFLNAFALIEFFKAVLRLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIG
                     YGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLA
                     FFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSG
                     MFSRWLAKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFD
                     FWNWLQNGAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPLPSARTRT
                     LLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGV
                     FIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGI
                     GSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLVIGEPNFAGIVGLSNTAFTL
                     RVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQVLPAPGAAPAEPLPPGEPT
                     L"
     gene            complement(39254..39976)
                     /gene="glnQ"
                     /locus_tag="ACHY1N_002428"
     CDS             complement(39254..39976)
                     /gene="glnQ"
                     /locus_tag="ACHY1N_002428"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_process: GO:0003333 - amino acid transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HFS4044728.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     DPQVLIKNPPSQRLQEFLQHVS"
     gene            complement(39973..40632)
                     /gene="glnP"
                     /locus_tag="ACHY1N_002429"
     CDS             complement(39973..40632)
                     /gene="glnP"
                     /locus_tag="ACHY1N_002429"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HFS4044729.1"
                     /translation="MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFAR
                     TFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            complement(40771..41517)
                     /gene="glnH"
                     /locus_tag="ACHY1N_002430"
     CDS             complement(40771..41517)
                     /gene="glnH"
                     /locus_tag="ACHY1N_002430"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015599 - ATPase-coupled L-glutamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:1903803 - L-glutamine import across plasma
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HFS4044730.1"
                     /translation="MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDEL
                     RDKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            complement(41921..42424)
                     /gene="dps"
                     /locus_tag="ACHY1N_002431"
                     /gene_synonym="pexB"
     CDS             complement(41921..42424)
                     /gene="dps"
                     /locus_tag="ACHY1N_002431"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016722 - oxidoreductase activity, acting
                     on metal ions [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HFS4044731.1"
                     /translation="MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLW
                     FIESNIE"
     gene            complement(42723..43610)
                     /gene="rhtA"
                     /locus_tag="ACHY1N_002432"
     CDS             complement(42723..43610)
                     /gene="rhtA"
                     /locus_tag="ACHY1N_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HFS4044732.1"
                     /translation="MPGSLRKMPVWLPIIILLVAMASIQGGASLAKSLFPLVGAPGVT
                     ALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGVSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACW
                     AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGALQAGEALWHWSVIPLGLAVAILS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAAS
                     MGSTLTVRKESKIKELDIN"
     gene            43845..43910
                     /locus_tag="ACHY1N_002433"
     CDS             43845..43910
                     /locus_tag="ACHY1N_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044733.1"
                     /translation="METFCYMKWPVRHHKSRRVSH"
     gene            43963..44478
                     /gene="ompX"
                     /locus_tag="ACHY1N_002434"
     CDS             43963..44478
                     /gene="ompX"
                     /locus_tag="ACHY1N_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HFS4044734.1"
                     /translation="MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKM
                     GGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASI
                     YGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
     gene            complement(44527..46110)
                     /gene="opgE"
                     /locus_tag="ACHY1N_002435"
     CDS             complement(44527..46110)
                     /gene="opgE"
                     /locus_tag="ACHY1N_002435"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HFS4044735.1"
                     /translation="MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTA
                     AFTAILLLLWRTLPRVQKVLVGVSSLVAACYFPFAQAYGAPNFNTLLALHSTNMEEST
                     EILTIFPWYSYMVGIFIFVLGVIAIRRKKESEKARWNTFDSLCLVFSVATFFVAPVQN
                     LAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQT
                     YVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVD
                     GKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADK
                     NTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLY
                     TMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVP
                     FMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGSIYITNF
                     QLQKVDYNHLGTDIFDPKP"
     gene            complement(46382..46510)
                     /gene="mntS"
                     /locus_tag="ACHY1N_002436"
     CDS             complement(46382..46510)
                     /gene="mntS"
                     /locus_tag="ACHY1N_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HFS4044736.1"
                     /translation="MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK"
     gene            46696..47163
                     /gene="mntR"
                     /locus_tag="ACHY1N_002437"
     CDS             46696..47163
                     /gene="mntR"
                     /locus_tag="ACHY1N_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-binding transcriptional regulator
                     MntR"
                     /protein_id="HFS4044737.1"
                     /translation="MSRRAGTPTAKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK"
     gene            47160..48278
                     /gene="ybiR"
                     /locus_tag="ACHY1N_002438"
     CDS             47160..48278
                     /gene="ybiR"
                     /locus_tag="ACHY1N_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HFS4044738.1"
                     /translation="MSLPFLRTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERRLAMFMVLAAALLSTFLTNDVAL
                     FIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTPIGNPQNILIWGRSGLSFAGFI
                     AQMAPLAGAMMLTLLLLCWCCFPGKALQYHTGVQTPEWKPRLVWSCLGLYIVFLTALE
                     FKQELWGLVIVAAGFALLARRVVLSVDWTLLLVFMAMFIDVHLLTQLPALQGVLGNVS
                     HLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLVWAVNVGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHLYSIPMLLCAALVGYVLLVILPAN"
     gene            complement(48337..49257)
                     /gene="ldtB"
                     /locus_tag="ACHY1N_002439"
     CDS             complement(48337..49257)
                     /gene="ldtB"
                     /locus_tag="ACHY1N_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HFS4044739.1"
                     /translation="MNMKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVIT
                     IPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGIV
                     INSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDI
                     KFLFEKVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKS
                     VQTVTGQPDVDQVVLDEAIKNRSGMPVRLN"
     gene            49476..51068
                     /gene="ybiT"
                     /locus_tag="ACHY1N_002440"
     CDS             49476..51068
                     /gene="ybiT"
                     /locus_tag="ACHY1N_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HFS4044740.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
                     KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPL
                     FKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEI
                     TPERVIDFSGNYEDYLRSKGIE"
BASE COUNT        12271 a        12987 c        13635 g        12234 t
ORIGIN      
        1 atttttaatg aaaatgagca taaaaccaag acatataatg cttggcagct ttatgctctt
       61 ctgattggct gtatgtttga tgacaaaaaa ttagcgcaag aggacaaaaa atcaccttgc
      121 gctaatgctc tgtctcaggt cactaatact atctaaatag ttgattcata gtgactgggt
      181 atgttgtgtt ttgtcgtatt ttgtagtcta ttatttagac tgagtcaatt ataagacgtt
      241 gatattaatg gtttttactg tttcacattc aactttttta tactaacttg agcgaaacgg
      301 gaaggtaaaa agacaaaaag ttgtttttaa tacctttaag tgataccaga tggcattgcg
      361 ccatctggca gagtgattaa ctaaacatcg cagtaatcga ggcgcttgcc agagagtgga
      421 aatgaacgtt aaacccgacc atcgcgccgc tggcaccttc atcgacatca atacgttcta
      481 catccagcgc gtgaacggta aaaatgtagc gatgagtttc gcctttcggc ggtgctgcgc
      541 catcgtatcc ggttttacca aaatcggtac gcgtctgcaa aacgccgtct ggcattgcta
      601 ccagaccaga gccaaaccct tgcggtaata cgcgtgtatc agcgggtaag ttaacaacta
      661 cccagtgcca ccagccggag ccggttggcg catccgggtc gtagcaggtg acaacaaaac
      721 ttttcgttcc cgcaggaact tcatcccacg ccagatgcgg tgaaatatta tcgccatcgt
      781 aacccatgcc gttaaagaca tgacgatgcg gcaacttatc gccatcgcgc agatcgttac
      841 tgatgagttt catgaaccct cctttcttgt ttgcagaaag tgtagccaga aaccctcacg
      901 ctgacttccc gttattggca aaaaaatgtt tcatcctgta ccgcgcggtt aaccgctgcg
      961 gtcagacgct gcaactgttg cgggagaata atatagggcg gcatcaggta aatcagtttg
     1021 ccaaaaggcc ggatccagac accctgttcg acaaagaatt tttgcagcgc cgccatattc
     1081 accggacgag tggtttcgac cacaccgatt gcccccagta cgcgcacatc ggcaaccatt
     1141 tcggcatcac gggcgggggc aagttgctcg cgcagctgta cttcaatagc cgccacctgc
     1201 tgctgccatt cgccggattc gataatcgcc aggctggcgt ttgctgccgc gcaggccagc
     1261 ggattgccca taaaagttgg cccgtgcata aagcaaccgg cttcgccgtt actgatggtt
     1321 tccgcaacct cgcgcgtggt gagcgtggcg gaaagggtca ttgtgccgcc ggttaaggct
     1381 ttaccgaggc acaaaatgtc cggcgcgatt tctgcatatt cacaggcaaa cagtttgccg
     1441 gtacgaccaa atccggtggc gatctcgtcg gcaatcagca agataccttc gcgatcgcac
     1501 attttgcgga ttcgttttaa ccattccgga tggtacatgc gcatcccgcc tgcgccctgg
     1561 acaatcggct caatgatcac cgctgcgatt tcatgacgat gcgccgccat caggcgggca
     1621 aaaccaacca tatcacgctc atcccattca ccatccatgc ggctttgcgg ggcgggagca
     1681 aacaagtttt ctggcagata gcctttccac aggctgtgca ttgagttgtc cggatcgcac
     1741 accgacatcg cgccaaaggt atcgccatga taaccattgc ggaaggtcag aaaacgctgg
     1801 cgcgcttcgc ctttggcttg ccagtactgc aacgccattt tcatcgccac ttccaccgct
     1861 acggaaccgg agtccgcgag aaaaacgcac tccagtggtt gcggcgtcat cgccaccagt
     1921 ttgcggcaca gctcaatggc tggcgcatga gtgataccgc caaacatcac atgcgacatg
     1981 gcatcaattt gcgtcttcat cgccgcatta agctgcgggt gattgtagcc gtggatcgcc
     2041 gcccaccagg acgacatacc gtcaaccagg cgtctgccgt cagacaaaat tagctcgcaa
     2101 ccttcggcgc tcgccaccgg ataaaccggc agaggggagg tcatggatgt gtatgggtgc
     2161 cagatatggc gttggtcaaa ggcaatatcg tccgttgtca taatcgactt gtaaaccaaa
     2221 ttgaaaagat ttaggtttac gagtctacac cgaattaaca acaaaaaaca cgttttggag
     2281 aagccccatg gctcaccgcc cacgctggac attgtcgcaa gtcacagaat tatttgaaaa
     2341 accgttgctg gatctgctgt ttgaagcgca gcaggtgcat cgacagcatt tcgatcctcg
     2401 tcaggtgcag gtcagcactt tgctgtcgat taagaccgga gcttgtccgg aagattgcaa
     2461 atactgcccg caaagctcgc gctacaaaac cgggctggaa gccgagcggt tgatggaagt
     2521 tgaacaggtg ctggagtcgg cgcgcaaagc gaaagctgcg ggatcgacgc gtttctgtat
     2581 gggcgcggcg tggaagaatc cccacgaacg cgatatgccg tacctggaac aaatggtgca
     2641 gggggtaaaa gcgatggggc tggaggcgtg tatgacgctg ggcacgttga gtgaatctca
     2701 ggcgcagcgc cttgcgaatg ccgggctgga ttactacaac cacaacctgg acacctcgcc
     2761 ggagttttac ggcaatatca tcaccacccg cacttatcag gaacgcctcg atacgctgga
     2821 aaaagtgcgc gatgccggga tcaaagtctg ttctggcggc attgtgggct taggcgaaac
     2881 ggtaaaagat cgcgccggat tattgctgca actggcaaac ctgccgacgc cgccggaaag
     2941 cgtaccaatc aacatgctgg tgaaggtgaa aggcacgccg cttgccgata acgatgatgt
     3001 cgatgccttt gattttattc gcaccattgc ggtcgcgcgg atcatgatgc caacctctta
     3061 cgtgcgcctt tctgccggac gcgagcagat gaacgaacag actcaggcga tgtgctttat
     3121 ggcaggcgca aactcgattt tctacggttg caaactgctg accacgccga atccggaaga
     3181 agataaagac ctgcaactgt tccgcaaact ggggctaaat ccgcagcaaa ctgccgtgct
     3241 ggcaggggat aacgaacaac agcaacgtct tgaacaggcg ctgatgaccc cggacaccga
     3301 cgaatattac aacgcggcag cattatgagc tggcaggaga aaatcaacgc ggcgctcgat
     3361 gcgcggcgtg ctgccgatgc cctgcgtcgc cgttatccag tggcgcaagg agccggacgc
     3421 tggctggtgg cggatgatcg ccagtatctg aacttttcca gtaacgatta tttaggttta
     3481 agccatcatc cgcaaattat ccgtgcctgg cagcagggtg cggagcaatt tggcgtcggt
     3541 agcggcggtt ccggtcacgt cagcggttat agcgttgcgc atcaggcgct ggaagaagaa
     3601 ctggccgagt ggctgggcta ttcgcgggca ctgctattta tctctggttt tgccgctaat
     3661 caggcagtta ttgccgcgat gatggcgaaa gaggaccgta ttgctgccga ccggcttagc
     3721 catgcctcat tgctggaagc tgccagttta agcccgtcgc agcttcgccg ttttgctcat
     3781 aacgatgtca ctcatttggc gcgattgctt gcttccccct gtccggggca gcaaatggtg
     3841 gtgacagaag gcgtgttcag catggacggc gatagtgcgc cactggcgga aatccagcag
     3901 gtaacgcaac agcacaatgg ctggttgatg gtcgatgatg cccacggcac gggcgttatc
     3961 ggggagcagg ggcgcggcag ctgctggctg caaaaggtaa aaccagaatt gctggtagtg
     4021 acttttggca aaggatttgg cgtcagcggg gcagcggtgc tttgctccag tacggtggcg
     4081 gattatctgc tgcaattcgc ccgccacctt atctacagca ccagtatgcc gcccgctcag
     4141 gcgcaggcat tacgtgcgtc gctggcggtc attcgcagtg aagaggggga cgctcggcgc
     4201 gaaaaactgg cggcactcat tacgcgtttt cgtgccggag tgcagggttc gccgtttacg
     4261 cttgcggatt cacgtagcgc catccagcca ttgatcgtcg gtgataacag ccgtgcgtta
     4321 cagctggcag aaaaactgcg ccagcaaggt tgctgggtga cggcgattcg cccgccaacc
     4381 gtacccgctg gcaccgcgcg gctacgcctg accttaaccg ccgcccatga aatgcaggat
     4441 attgaccgtt tgctggagat gctgcatggc aacggttaat aaacaagcca ttgcagcggc
     4501 atttggtcgg gcagccgcgc actatgagca acacgcagat ctacagcgcc agagtgctga
     4561 cgtcttactg gcaatgctcc cacagcgtaa atacacccac gtactggacg cggggtgtgg
     4621 gccaggctgg atgagccgcc actggcgaga gcgtcacgcg caggtgacgg cgttagatct
     4681 ctcgccgcca atgcttgttc aggcacgcca gaaggatgcc gcagaccatt atctggcggg
     4741 agatatcgaa tccctgccgt tagcgactgc gacgttcgat cttgcatgga gcaatctcgc
     4801 ggtgcagtgg tgcggtaatt tatccacggc actccgcgag ctgtatcggg tggtgcgccc
     4861 cggaggcgtg gtcgcgttta ccacgctggt gcagggatcg ttacccgaac tgcatcaggc
     4921 gtggcaggca gtggacgagc gtccgcatgc taatcgcttt ttaccaccag gtgcaatcga
     4981 acagtcactg aacggcgtgc attatcaaca tcatattcag cccatcacgc tgtggtttga
     5041 tgatgcgctc agtgccatgc gttcgctgaa aggcattgga gccacgcatc ttcatgaagg
     5101 gcgcgacccg cgaatattaa cgcgttcgca gttgcagcga ttgcaactgg cctggccaca
     5161 aaaacagggg cgatatcccc tgacgtatca tctttttttg ggagtgattg ctcgtgagta
     5221 aacgttattt tgtcaccgga acggataccg aagtggggaa aactgtcgcc agttgtgcac
     5281 ttttacaagc cgcaaaggca gtaggttatc ggacggcagg ttataaaccg gtcgcctctg
     5341 gcagcgaaaa gaccccggaa ggcttacgta atagtgacgc gctggcgtta cagcacaaca
     5401 gcagcctgca gctggattac gcaacggtaa atccttacac cttcgcagaa cccacctcgc
     5461 cgcacatcat cagcgcgcaa gagggcaggc cgatagaatc attggtaatg agcgccggat
     5521 tacgcgcgct tgaacaacag gctgactggg tgttagtgga aggtgctggc ggctggttta
     5581 cgccgctttc tgacactttc acttttgcag attgggtaac acaggaacaa ctgccggtga
     5641 tactggtagt tggtgtgaaa ctcggctgta ttaatcacgc gatgttgact gcgcaggcaa
     5701 tacaacacgc cggactgact ctggcgggtt gggtggcgaa cgatgttacg cctccgggaa
     5761 aacgtcacgc tgaatatatg accacgctca cccgcatgat tcccgcgccg ctgctgggag
     5821 agatcccctg gcttgcagaa aatccagaaa atgcggcaac cggaaagtac ataaaccttg
     5881 ccttgttgta gccatcctgt atttggttaa attgcgagcg agatcgcgtc ttcgattgac
     5941 tgcaatttaa ccaattaaat tctaaaataa tcacgaaaaa aattttactt ccgcctcatg
     6001 cggcgaatgt gggaattgcc caggcggcgg gggatagggg ctggagacag ttatccacta
     6061 ttcctgtgga taaccatgtg tattagagtt agaaaacacg aggcaagcga gagaatacgc
     6121 ggcttgcacg cgaattggcg ttaaagacgg ctcaaagaaa tatcttttat tttttaactg
     6181 gttagataaa tgcaatggca gtcactgaac aggcatctct tgccataaaa ctgtcatcac
     6241 tcatcttgac aaatgttaaa aaagccgttg ctttggggat aacccggtaa ggccggagtt
     6301 ttatctcgcc acagagtaaa ttttgctcat gattgacagc ggagtttacg ctgtcacaga
     6361 aatattatgg tgatgaactg tttttttatc cagtataatt tgttggcata attaagtacg
     6421 acgagtaaaa ttacatacct gcccgcccaa ctccttcagg tagcgactca tgagtaaacc
     6481 gttcaaactg aattccgctt ttaaaccttc tggcgatcag ccagaggcga ttcgacgtct
     6541 cgaagagggg ctggaagatg gcctggcgca ccagacgtta cttggcgtga ctggctccgg
     6601 gaaaaccttc accattgcca atgtcattgc tgaccttcag cgcccaacca tggtacttgc
     6661 gcccaacaaa acgctggcgg cccagctgta tggcgaaatg aaagagttct tcccggaaaa
     6721 cgcggtggag tatttcgtct cctactacga ctactatcag ccggaagcct atgtaccgag
     6781 ttccgacacc ttcattgaga aagatgcctc ggttaacgaa catattgagc agatgcgttt
     6841 atccgccacc aaagcgatgc tggagcgacg tgatgtggtt gtagtggcgt ctgtttccgc
     6901 gatttatggt ctgggcgatc ctgatttata tctcaagatg atgctccatc tcacggtcgg
     6961 tatgattatc gatcagcgcg cgattctgcg ccgactggcg gagctgcaat acgctcgtaa
     7021 tgatcaagca ttccagcgtg gtactttccg cgttcgtggc gaggtgattg atatcttccc
     7081 ggcagaatcg gatgacattg cacttcgcgt ggaactgttt gacgaggaag tggaacgatt
     7141 gtcgttattt gacccgctaa ccgggcagat tgtttccacc attccacgtt ttaccatcta
     7201 cccgaaaacg cactacgtca caccgcgcga gcgcatcgta caggcgatgg aggagatcaa
     7261 agaagagctg gccgccagac gcaaagtgct attggaaaac aacaaactgc tggaagagca
     7321 gcggctgacc cagcgtaccc agtttgatct ggagatgatg aacgagctgg gctactgttc
     7381 ggggattgaa aactactcgc gcttcctctc cggtcgtgga ccgggtgagc caccgccgac
     7441 gctgtttgat tacctccctg ccgatgggct gctggtggtc gatgaatctc atgtcaccat
     7501 tcctcaaatt ggcggcatgt atcgcggtga ccgggcgcgt aaagagacac tggtggagta
     7561 cggcttccgc ctgccatcag cgctggataa ccgtccgctt aagtttgaag agttcgaagc
     7621 attagcgccg caaaccatct atgtttcggc gacgccgggt aattacgagc tggaaaaatc
     7681 cggcggcgat gtggtggatc aggtggtgcg tccaaccgga ttgcttgacc cgattatcga
     7741 agtgcggccg gtggcgacac aggttgatga tcttctttcg gagattcgtc agcgagcggc
     7801 aattaacgaa cgcgtactgg tcaccacact gaccaagcgg atggcggaag atcttaccga
     7861 atatctcgaa gaacatggcg agcgcgtgcg ttatcttcac tcagatatcg acaccgtcga
     7921 acgtatggag attatccgcg acttgcgtct gggtgagttc gacgtgctgg tagggatcaa
     7981 cttactgcgc gaaggtctgg atatgccgga agtgtcgctg gtggcgatcc tcgacgctga
     8041 caaagaaggc ttcctgcgtt ccgaacgttc gttgatccag accattggtc gtgcggcacg
     8101 taacgttaac ggtaaagcga ttctctacgg cgataagatc accccatcaa tggcgaaagc
     8161 gattggcgaa accgaacgtc gccgtgagaa acagcagaag tacaacgagg aacacggcat
     8221 tacgccgcaa ggcttgaaca agaaagtggt cgatatcctg gcgctggggc agaacattgc
     8281 caaaaccaaa gcgaagggca gaggaaaatc gcgcccgatt gttgagccgg ataatgtgcc
     8341 gatggatatg tcgccgaaag cgttgcagca gaaaatccat gaactggaag ggctgatgat
     8401 gcaacacgcg cagaatctgg agttcgaaga agcggcacaa attcgtgacc agttgcatca
     8461 gttgcgtgag ttgtttattg ccgcatcgta acaggatagc gaagaagact gatgacaaac
     8521 ggaaaacagc ctgatgtgct acgcttatca ggcctacatt ttctccgcaa tatattgaat
     8581 ttgcgcggtt tgtaggccgg ataaggcgtt cacgccgcat ccggcataaa caacgcgcac
     8641 tttgtcttca ataggaagcc ggaattttcc ttcggatttc cgttaaccta aagcctgtaa
     8701 cgccttttcc agcgcgttat gtaacaactg gcggtcatga cgatacggaa tatcgctggc
     8761 ctccagtacc tcctggatca caatccgctc tttcaccgcc gagacatcca cttttggccc
     8821 gacgatgacc gcatcaatga cctttttacc aacatactgc tccataattg ccagcttgct
     8881 ttccagcttc aaattagccg caggtaaact caactcacgc cccagattgc cgatataaac
     8941 catcggcgct ggcgtgcggc gtaatgcctg ggcgatttcc ttcagcagca gaattggcat
     9001 caggctggta taaaaactgc caggcccaat aatgatgaga tccgcttcat tgatagcgtg
     9061 aaccgcctca cgcgttgcgg gtacattagg cgttaacaat aactcttgaa tcggcgtagt
     9121 taactggtcg atattgacct cgccgtaaac ttcatgcccc tgatcgtcaa tcgccatcag
     9181 atcaacagga tgctctgaca ttggaatcaa atgcgtatcc actttcagca gattacgaat
     9241 taaattgatg gcttccagag gccgcacgct aaggtgatcc agcgccttta acatcaagtt
     9301 tccgagatta tgaccggaaa gttcgccatt gccaccaaaa cggtattcaa acatcgcgga
     9361 ggcgacgctc ggttccgtta tcagctggtt gaggcagttg cgcatatcgc cccaggcaat
     9421 gccgccttct gaacggcgaa tacgccccgt cgagccacca ttatcggtgg tggtgacgat
     9481 acccgttaaa cgagaaccca aagacgaaag tgatgagaga acgcgtccca gtccatgccc
     9541 tccgccgaga gcaacgacac gatcaagatc agccagcgta cgattgcgca tatagtttcc
     9601 tggagtcaga ttatccgcgc tacagtagcg caaattgcgg ggaaacagca attaacctgc
     9661 caatattgag gatacaaact attttcttct acctctaaag gacgatgcac gctatgcctc
     9721 cctgatgatg tatatcaaag taaagccgcc attttccctt attctgtagc gaaatagcac
     9781 gatcatgacg ctatatacat gattacatag cgaaagtgtg gatggtaaaa atctcattta
     9841 cacgctagta tcggcataac cactaaacac tctagcctct gcacctgggt caactgatac
     9901 ggtgctttgg ccgtgacaat gctcgtaaag attgccacca gggcgaagga agaaatgact
     9961 tcgcctcccg tatctggaaa ggtgtacatg gcttcacaac tgactgatgc atttgcgcgt
    10021 aagttttact acttgcgcct gtcgattacc gatgtgtgta actttcgttg cacctactgc
    10081 ctgccggatg gctacaaacc gagcggcgtc accaataaag gctttcttac cgtcgatgaa
    10141 attcgccggg ttacgcgcgc cttcgccagt ctgggcaccg aaaaagtgcg cctgacaggc
    10201 ggtgagccgt ctttacgccg cgactttacc gatatcatcg ccgctgtgcg ggaaaacgac
    10261 gctatccgcc agattgcggt caccaccaat ggttaccgtc tggaacgcga tgtggcgaac
    10321 tggcgcgatg cgggacttac tggcattaac gtcagtgtcg acagtctgga cgcccgccag
    10381 tttcacgcta ttaccgggca ggataaattc aaccaggtca tggcggggat tgatgctgca
    10441 tttgaggccg gttttgagaa ggtcaaagtc aataccgtgc tgatgcgtga tgttaatcat
    10501 caccagctcg acacctttct gaactggatc cagcatcgcc ctatccagct gcgtttcatc
    10561 gaactgatgg aaacgggcga gggcagcgag ctcttccgta agcatcacat ctctggtcag
    10621 gttctgcgtg acgagctact gcgtcgcggc tggatccacc aattacgtca acgcagcgac
    10681 ggtcccgcgc aagtcttttg ccatccagat tacgccggag agattggcct tatcatgccg
    10741 tatgaaaaag acttctgcgc cacttgcaac cgcctgcgcg tttcctccat tggtaaactc
    10801 catctctgcc tgtttggtga aggcggcgtt aacctgcgcg atctgctgga agacgatacc
    10861 cagcaacagg cgctggaagc gcgtatttca gcggcgctgc gggagaagaa acagacccat
    10921 ttcctgcatc aaaacaacac cggtattacg caaaacttat cgtacattgg cggctaaaac
    10981 gtcaaaagga gagatcagat gagtcaggta agcactgaat ttatcccgac ccgtattgct
    11041 attcttacgg tttctaatcg tcgcggtgaa gaagacgata cctccggtca ctatctgcgc
    11101 gattcggcgc aagaagcggg ccatcacgtt gtcgataaag ccattgtgaa agaaaaccgc
    11161 tacgctattc gcgctcaggt atctgcgtgg atcgccagcg acgatgtaca agtggtattg
    11221 attacgggtg gtactggcct gacggaaggt gatcaggctc ccgaagcatt gctgccgttg
    11281 ttcgaccgtg aagttgaagg ttttggtgaa gtgttccgga tgttgtcttt tgaagagatt
    11341 ggcacttcca cgttgcaatc tcgtgcggta gcgggcgtcg ccaacaaaac gctgattttc
    11401 gccatgccgg gttcgaccaa agcgtgccgt accgcatggg aaaatatcat cgcgccgcag
    11461 ctggatgccc gtacgcgtcc gtgtaatttc catccacatt tgaagaaata agtatgtcgc
    11521 aactgaccca tatcaacgcc gctggcgaag cgcacatggt ggatgtctcc gccaaagcgg
    11581 aaaccgtgcg tgaagcgcgg gcggaagcct ttgtcaccat gcgcagcgag acgctggcga
    11641 tgattattga tggtcgccac cacaaaggcg acgtatttgc cactgcgcgt attgccggta
    11701 ttcaggcggc aaaacgcacc tgggatctga tcccgctctg tcatccgctg atgctcagca
    11761 aagttgaagt caatttacag gccgagccgg agcacaatcg ggtgcgtata gaaaccttat
    11821 gccgcctgac cgggaaaacc ggtgtcgaaa tggaagcatt aaccgcggcc tccgtggcgg
    11881 cgctgaccat ttatgacatg tgcaaagcgg tgcaaaaaga tatggtgatt ggtccggtac
    11941 gtttgctggc gaagagcggc ggcaagtcgg gtgactttaa ggtggaagcg gatgattaaa
    12001 gttctttttt tcgcccaggt gcgcgagttg gtgggaacag atgcaaccga agtggctgcg
    12061 gatttcccaa ctgttgaagc gttacgccag cacatggctg cgcagagcga tcgctgggcg
    12121 ctggcgctgg aagatggcaa attactggct gccgtcaacc agacgctggt gagttttgac
    12181 catccgctga ctgacggcga cgaagtagct ttcttcccgc cggtaaccgg aggttaagat
    12241 ggcagaaacc aaaattgttg ttggtccgca gccgttcagc gtaggagaag agtacccgtg
    12301 gctggcggag cgtgacgaag acggtgcggt agtcaccttt actggtaagg tgcgcaacca
    12361 taacctgggc gacagcgtca aagcattaac cctcgaacac tatccgggga tgactgaaaa
    12421 agcactggca gaaattgttg atgaagcgcg taaccgctgg ccgctggggc gcgtcactgt
    12481 gattcaccgc atcggggaat tatggccggg cgatgaaatc gtttttgtcg gtgtcaccag
    12541 tgcgcatcgc agcagtgcgt ttgaagccgg gcagtttatt atggattatc tcaaaacccg
    12601 cgcaccgttc tggaagcgcg aagccacgcc ggaaggcgac cgctgggttg aagcccggga
    12661 gagcgatcag caggcggcaa aacgctggta gttttttgtt agccggataa ggcaccgctg
    12721 cgtccggcaa tttcaccgct cagtacatac gtttacgctg cgtcgatgca cagcctcatc
    12781 attttgcagt atccttaaga tattccttat atcttcagga gatcgtcatg gacagattcc
    12841 cacgttctga ttcaatcgta caaccccggg ctggcttgca aacttatatg gcgcaagtct
    12901 atggctggat gaccgttggc ttgttgctga ccgcatttgt tgcctggtat gcggctaatt
    12961 ccgcggccgt gatggagctg ttgttcacta accgtgtctt tttaatcggt ctgatcatcg
    13021 cgcaattagc attggttatt gtgttatcag cgatgattca aaagctgagc gcaggtgtaa
    13081 cgacgatgct ctttatgctt tattcggcgc tgacgggtct tacgctttcc agtatattca
    13141 ttgtctatac cgctgcttct atcgccagta ctttcgtcgt tactgccggg atgttcggcg
    13201 caatgagcct gtacggttac accacgaagc gcgatttaag tggctttggc aatatgctgt
    13261 ttatggcgtt aatcggcatt gtgctggcat cgctggtcaa cttctggttg aaaagcgaag
    13321 cattgatgtg ggcagttacc tacatcggcg tgattgtctt tgtcggattg acggcgtatg
    13381 acacgcagaa actgaaaaat atgggtgagc agattgatac ccgcgacacg tcgaacctgc
    13441 gcaaatattc cattcttggc gcgttaacct tgtatctgga cttcatcaac ctgttcctga
    13501 tgttgttgcg gatcttcggc aaccgccgtt aaattctctt cttcctgctg atcccggcct
    13561 ggagccggga tttttttcgg attttataaa gactattccg ctcatttaca tgagaactga
    13621 atcgcggcaa atgccagact atgtccacta cgtaatttca gggacagata acgcatttga
    13681 acagacaatc cactgctact caattacagc aaaaaagtgc ttcgctcagc aaaatgctgc
    13741 ttctcatttg gtggttaaca gcagctggag tatgggctac ggcaggctgt gcctggatat
    13801 ttcagcattt gcattgggtt acgtcacaaa agtctccagg tgcgtttgtc ttcgctttgg
    13861 ctgcgctgat aataggtggt ctctggttaa acaacgccct gaaaagactg aatgtatcag
    13921 gcgcatgtct ggtctatctg ctaataatcc ttcttgttgg ctttctcttc gccagccttt
    13981 ataccttttc gagcatagcg acggtaatgg gaattacggg agggatgttt gccgcaatgg
    14041 cgctgatttg ctcttgtagt aatagggtta tcccaccagt cagacagtta tattcatata
    14101 ttttctgtgg tttgagtatt gcttttgttg ttaacctgat ccttaccagc agtttttccg
    14161 tgtggttagc gagtattttg actgtcttta tctggggcat tacggctgcc tgtgaagcaa
    14221 caacactgga agatttgatc cgtgttgccg acacctctga aatttcaggt tctcttcgct
    14281 gtatcgttcc tggggcaata acactctatt ttagtatttt aagcgtcctc tttagaatta
    14341 ctgtaacagt tcttgaattt attaatggtt tagtgtggta gtgcgaattg acgagtttta
    14401 ttgcgttaat tggaatagat aatgatattt aacttaagga tataaaaata atgaattcgc
    14461 gctcagcaaa taacataact aatgattttc agcacgaagc caggatatta aacagcatat
    14521 ggctcattac cgctttaggt ttggtgacaa ccgcaggact ggcctgggta gcgaagtatc
    14581 tcgaaattac ggcaacaaaa tatgattcac cgcaaatgta tgtcgccata ggattattat
    14641 tactttgtat gtatggctta agtaaggata tcaacaagat aaatgccgtc atcgcaggcg
    14701 taatatatct atttttactc tctttggtgg cgattgtcgt tgctagttta gctcctgtac
    14761 ctgccattat cgtcgtgttc agcactgcgg gcgcgatgtt tttaatcagt atgctggccg
    14821 gtttattatt taatgttgat cctggttctc accgttttat cattatgatg acgttgacag
    14881 ggttggccct ggtgatcatc atgaatgccg cattaatgag tgaacgaccc gtttgggtaa
    14941 taagttgctt aatgattgtg ttatggtcag gcattatctc gcatggacga aataagctcc
    15001 ttgaattggc ggggaaatgc catagtgaag agttgtggag tccggttcgt tgcgctgtta
    15061 caggtgcatt aacactctat tactatttta tcggcttctt tgggatactt gccgcgatag
    15121 ctataacgct tgtctggcaa aggcatacgc gtttttttca ttagtcgtaa atgcagatac
    15181 taaagaactt aactaaactt cacatcgccg cttcattttt cgcccgtagc ttcttcgcct
    15241 ggctttccag tagcaggtaa cagatcagcg ccagcagcag cgggataaag taatacagga
    15301 cgcgataagc gagcagggcg gcgataatgc tccctttcga ggtatgctcc ccagccagta
    15361 gtgcgataaa caccgcttcc agcacaccga tccccgccgg aatatgcacg atgacgccag
    15421 caatactact aaccagtaac acgcccagta caaagaaata gttcacgctt tgaccaagta
    15481 acagccagat aatcgccccc attaccatcc agttaacgct ggaaatcagc atctgagcga
    15541 gggcgaattt ccatgaaggc agcaccagct tttgcccttt gatggtcata tggcggtgct
    15601 tcgcgaaagc gcaaaaccac aaataaaccg cgataatcat cagtaagcca atgccgagaa
    15661 tacgcagcgt agtttgatcg acataccagt gatccggcaa ctccaccacg cctgcggtaa
    15721 agataatccc tgccagtaaa atatagccca gccagttggt ggtaatactg agcgagaaaa
    15781 tccgcgtaat agtgctgccc ggtaacccta gtcgggagta caaacgatag cgcataccaa
    15841 tgccgccgac ccaggtactg agcgtcaggt tgaaggcgta gcagataaac gacaccagca
    15901 tcacctggcg cttcgccagt ttgtgaccgc agtaaaagcg ggcgagcagg tcatagcagc
    15961 cgtaaatcag atagctgacg accaccagcc cgaccgcact aagcagcgca acgcgattgt
    16021 agtcgcggat gaccttccag acctcttccc agtccacttt tttggcgtag accaccagca
    16081 acacaatcac cgcgataaaa aacagccagg tgaggatctt ctttgctaag cgccagcgcg
    16141 ggtgtgattt actcatcagg gttttacccc cgtgttttca gtttctaccc gatcctgcgt
    16201 ttccattgtc ggttgtgcgg gcggatcaac ctgcgccaga cgtggtgtgt gtgccggaag
    16261 ccagccaacc agcgccggga agtggcgtaa aaagtggaac gccagcacgc ttttggtcag
    16321 gttccaccag gtgcgtttcg gcagcatggt ctcatcgacc tgctgacaat ctgcggcaat
    16381 aatgccgttc agattatcgc gcagcgtctg gttaaaatga cgatcgtgga tgatgacatt
    16441 tgcttcgaga ttcagtgaca aactgagcgg atcgagatta ctggacccta ctgtcgccca
    16501 gtgatcgtcc atcaatgcca ctttgccgtg gagcgggcgg cggcggtact caaatacctg
    16561 aacgccgcct ttaaccagat agttatacag caagcgcgca ccgactctga caatcggcat
    16621 atccggttcg ccctgaatga tcagtttgat ccgcaccccg cgccgtgccg ctttacgcaa
    16681 ggcgtgtaaa aatcgatagc cggggaagaa gtaggcgttg gcgataatga cttctcgccg
    16741 cgcctgagtg agcattttca gatagtgacg ttcaatatca tcgcgatgtt cttcgttatc
    16801 gcgccagacc agcaatacct gcgcttctcc cggctggcgg ttctcttccg ctttgtgatg
    16861 acgtcgccac cagcgtcgtg ccgcgctctg tccaggcagg ttttccagct caaactggag
    16921 aatatcttcg acaatcggcc cttcaaggcg taccgcgtaa tcctgtttag cctctggacc
    16981 gtagctggac atatgctcgg cggagtaatt cagcccgcca ataaaggcga tacgcgcgtc
    17041 gatcaccaca attttgcgat gcatccggcg aaacacattg gtgcgcatac caaaaaggcg
    17101 agggcgggga tcgtagtagc gaaataccac gccagctgcc gtcagttcat tgacaaactc
    17161 atcgctgaga tccggcgaac cgtagccatc cagcaagact tccgctttaa ccccgcgttg
    17221 cgctgctgcc agtagtgccg catgcagctg tttgccgacg tcatcctcaa accagataaa
    17281 cgtttcaaga atgatgcgtt cttgtgcctc gccaatcgcc ttaaacaccg cgggataata
    17341 ttgctcgccg ttttccagca actggatctt attgccttcg cgccagctac atttcataaa
    17401 tgaatctccg cacttaaagg ggcatgatca gaaaggtgtc gccatgtccg cagcggcaac
    17461 gcggttggcg cgctggcgct ggcatttttg acgtagatcc tgtccagtcg tagtagagga
    17521 aattgcaccg gaaacgtgcg cgccgggcgt ccgtgggcgc gggtaaaaat ctcatccagt
    17581 ccggcctgca cttttaacgg atgattagct ttttgccgcc agtcattgaa atcacccgcc
    17641 accaataccg gttcgccgtc cggtagctca ttcacccatt cggcgagcat cgcaagctgc
    17701 gcctgacggt gcgcctcacg caggcccaga tgtacgcaca tcacatgaat cgcttttccg
    17761 gtcatcggtg gcacaatgcg gcagtagagc acgccgcgct tttccgcacc atcgaccgaa
    17821 acatcgcgat tctcataatg ttcaatggga taacgcgaca gtacggcgtt gccgtgatgc
    17881 ccttccgggt atacggcatt gcgaccgtag gcaaaatcgc tccacatcgt gtcggcgaga
    17941 aactcgtagt gcgaggtatc gggccagttt tccacatgca gcggatgaac ttcgtgcgcg
    18001 cccatcactt cctgcaggca aacaatatcg gcgctgacgg tacgcaccgc gtcgcgaagt
    18061 tccggcaaaa tgaagcgtcg gttaaacgcg gtaaaacctt tgtgaatgtt gatggtgagc
    18121 accttgaacg aaaattgttg tgtttgatcg ggcataattt tcctgtcttt gcctcttatc
    18181 tcattgaaat agtgtagtcg gcgtcacaaa aaggtgcggt cttacggaat tttccgtaaa
    18241 gttcggtact ctgagtaagt agagataaat tcttcaggag agaagccatg aagtggcaac
    18301 aacgtgttcg tgtcgcaact ggtctaagtt gctggcagat tatgttgcat ttactggtag
    18361 tggcgctgct ggtggtgggc tggatgagta agactctggt tcacgtcggc gtgggattat
    18421 gcgcactgta ttgtgtcacg gtagtgatga tgttggtgtt tcagcgccac cccgagcaac
    18481 gctggcgtga ggtggcagac gtgctggaag agctgaccac gacctggtat tttggcgcag
    18541 cgctgattgt gctgtggctg ttgtcccgtg tactggaaaa caactttttg ctggcaattg
    18601 cagggctggc aatccttgcc ggcccggcgg tagtgtcttt gctggcgaaa gataagaagt
    18661 tacatcacct tacgtctaaa catcgcgtac gccgctgacc ctgtcgtggc cgttatcacc
    18721 agtagcggcc acaaactatt ccacacaata tccagactcg catccttcaa ataaatctgc
    18781 ttggtaatgt ccgtaaagtg gcgaataggg ttaatccacg tcaggttttg cagccatact
    18841 ggcatgtttt ccaccggaga aacgtaaccg gaaaggagaa tggcgggcat cataaaaaca
    18901 aacacgccga taaacgcctg ctgttgtgtc gagcagagtg atgaaatcaa cagaccgaat
    18961 cccaccagcg ataaaccgta aatcaccatc gtaaagtaga acagcgccag cgatccggcg
    19021 aaggggattt gatacgccca gataccaatc gccagcacaa tggtggcctg gaaggtggcg
    19081 acaattaacg ccggtacggc tttgccgatg aagatctgcc aggtggtgag cggcgaaacc
    19141 agtagctgat cgagcgtacc ttgttcacgt tcgcgggcga cggaaagtga agtgacgatc
    19201 attacgccga tagtggtgat catggcgatc agcgacggca ccacaaacca tttgtagtca
    19261 agattcgggt tataccagtt gcgtaccacc agctcgctgt tgttaggttt cggttttcct
    19321 tccagcagct cctgctgata atttttgacg atctgttgca ggtagttggc ggcaatttgc
    19381 gcactgttgg agttacgccc gtcgaggatc aactgcaacg gcgcggtctg gaaggtatcc
    19441 agtttgcgcg agaagtcagc cgggaaacgc accagtagta acgccttttg tgtgtcgatg
    19501 gttgggcgga tctcctgtgg gcttttcagc agcagcacat gagtaaaggc gctggcgcgg
    19561 gcaaaacgtt gggtcagctc caccgaatgc tcgccgttat cttcatcgta gatggcgatg
    19621 gtggcgttag tcacttccag cgtggcggcg aacgggaaca gaatcacctg aataagcaca
    19681 ggtaaaatca gaatcgcgcg ggtttgcggt tcgcgcagca gcgactgcaa ctctttgcgg
    19741 attaacgtcc ataagcgatg aaacatgctc ttctccctaa tccagccgac gtttggtttt
    19801 cagccacgtc aggccgataa acatcaccgc cgaagcgatc aaaaacagca cgtttaccac
    19861 cagcaccact ggaatattcc cggcgaggaa caggctttgc agggtgctga cgaaataacg
    19921 agcgggaata atgtacgtca ccgcgcggat caccgcgggc atactgtcga tctgaaaaat
    19981 aaagccggaa agcataatcg acggcagaaa agcggcgttc agggcgacct gagcggcatt
    20041 gaactggttg cgggtaatcg tggaaatcag cagccccatc cccagggtac tgagtaaaaa
    20101 caggctggag ataaaaaaca gaatcagcag cgacccgcga tacggcacgc cgagaataaa
    20161 cactgacacc agcatacaca gcaacatcgc cagcatcccg agaaagtaat aagggatcag
    20221 cttacacagc agcagttccg tgcgggtaat ctccgtagag agcagagcct ccatggtgcc
    20281 gcgttcccat tctcgcgcca ccaccagcga ggtgagaatc gcgccgatga ccgtcatgat
    20341 aatggtcacc gcaccgggga taatgaagtg ctggctaatc gccgccgggt taaaccagta
    20401 gcgggtttgt acatcaataa gcggttcaaa agtctgcccg ttgtcctccg ctcgctgcat
    20461 ttgccagatc tgccagatcc cttcgacata cccctgtaca aagttagcgg tattcggctc
    20521 actgccgtcg gtgatcacct gaatcggtgc ggtggcgttg gcgcgctcca tctgttccgc
    20581 aaaatccacc ggaataacca ccagaccgcg aattttcccc gcctgcattt tggcgatcag
    20641 ttcctgacgg ttatcgctga tggtggcgtc gatgtagggc gaaccggtca tggtgtgggt
    20701 gaaatccagc gccgcttcgc tacgctgttc cagtaaaatc ccgacccgca gcttgctgga
    20761 gtcgaggtta atgccgtaac caaaaataaa cagcagcaac agcgggatca ctaccgcaat
    20821 cagccagcta ctcggatcgc gaacgatctg ccgcgtctct ttgacgcaca gcgcccgcac
    20881 gcgacgccag gaaaggatcg ggttactcat tgctatgctc cttatcccag tcgtggatca
    20941 actgaataaa ggcttgctcc atggtgggat cgggttgctc atcgttagcc gactgtgctt
    21001 tcaaatcgtc cggcgtgccg ctggcgatta atttcccgcg gtacaccagg ccgatgcggt
    21061 cgcaatattc cgcttcatcc ataaagtggg tggtgaccat caccgtgacg cctttctcta
    21121 ccatgctgtt gatgtgcagc caaaattcac ggcgggtgag ggggtcaacg ccggaagtcg
    21181 gttcgtcgag aaacagaata tccggttcat gcatcagcga acaggccagc gccagccgct
    21241 gtttaaaacc taatggcagt tcatcggtgg cgtgggaggc aatacttttc aggccaaatg
    21301 cctcgctcat acgggagatt ttttcgttct gcgcccgacc gcgtaagcca tacacaccag
    21361 agaaaaagcg taaattctgt tcgaccgtca ggttgccata gagcgaaaac ttttgcgcca
    21421 tatagccgag atgctggcgc gctttaccgg aactctcttt cagatccatc cccagcacca
    21481 gcgcctgacc ggaggtcggc accagcaagc cgcacatcat cttaaaggtg gtcgatttcc
    21541 ccgcgccgtt tggcccgagc agaccaaaaa tctcccctcg tttaacggca aagttgacgt
    21601 gatcggtggc ggcaaaatca ccaaatttct tggttagttc tttcgcttcg atcaccgtct
    21661 cgccgggtgt gccttctacc gtatgcaata ttgcacccag cggcgattcc gaggttccgg
    21721 caccgcccag caaatcaata aacgcatctt caaaacgcgg cgtagtttcg ttgatgttga
    21781 tttccggcat cccttcggca tggcgaatat cgtctggtgt ggcctctttt ttgaggatca
    21841 gacgtaccga tttcccctga atcatgccgt cgctgacctg tggcagtttc aaggcgcgtt
    21901 gcaatagttt gcggttgccc tcgtgtggac tggtcatcag aaaactgcgt ccggccatgg
    21961 tttgtgtcag ggcttttggt tccccctgat acagcaactc gccttcgttc atcagtaaca
    22021 cgtcacggca ctgctcggct tcgtcgagat acgaggtact ccagaggatt aacatccctt
    22081 cgcctgccag ctcatgcacc atctgccaca gttcgcgccg tgagataggg tcaacgccga
    22141 cgccgggttc atcgagcagc aacactttcg gttcgcccac cagggtacag gccagaccga
    22201 gtttttgttt catcccaccg gagagcttgc ccgccaggcg tccggtaaac ggcccaagag
    22261 acgtaaactc cagcaggcga gcaaaagttt gcttacgtgc ctcgccggtg acgctgcgca
    22321 aatccgcgta cagattgagg ttctccatca ccgtgagatc ttcatacaga ccaaatttct
    22381 gcggcatata gccgagcacg gcgtgcagcg cgccgtcgtt tttgattgga tcaaagccaa
    22441 tcaccgtggc attgccgctg tcgggtttca gtaatcccgc cagcatccgc attagcgtgg
    22501 ttttacctgc accatccggc cccaccagcc ccgtcacata accggcgtga atggtacaat
    22561 cgagcggcgc gacggcgggc ttgtccatgc ccggaaagcg tttttctagg ccgttcagcg
    22621 tgataacggc atcattcatg tcctgcctcg ttaccgaatt gcaccgtcac cggcattccc
    22681 tggcgtaacg catcatcggc gtcggtcacc acaatacgca ggcgatagac gaggtcggta
    22741 cgcagatccg gtgtttcgac ggttttcggg gtaaattcag cagtcggcga aacgaaacca
    22801 atctgtccgt gatagggctt gtccgggcga ccatcggtat aaagcagcac tttgcgcccc
    22861 ggctgggcct ggtcaagatt ccgttcatca acataggcac gtacccacac cggacgcgtt
    22921 agtgaaacgg taaacaccgt gccaccttca ttgagaaccg tgcctggctc caccgcgcgc
    22981 gttaacagcg tgccatcaga cggtgctatc aacgttgagt cctgtaaatt cagctccgcc
    23041 tgcgccagtt gcgcctgcgc ctgttcgagg ctggctttcg cctgagcgat gtcctgttca
    23101 cggttaccgg aacggtactg acgcaattta tcctgtgctg atttcagcgt tgcctgtgcc
    23161 tggtcgcgcg aggagcgggc attttccagg tcatttgccg aaatggtgcg gcttttccac
    23221 agtccttgct ggcggttata gaagttctgc gcatagtcat aggcggcttg agcctgtttc
    23281 accgctgcgg cggcctgagc gatttcttca tcgcgatacc cggcaagcat cagatcatac
    23341 tgcgcctgtg ccaccgagac gcccgctttc gcctgcatca gggcaatctc atacggcttg
    23401 tgatccagtt cgcccagcac ctggcccgct ttgatagcat caccttcgtc caccgccagc
    23461 gattcaacgc gccccccaac acggaaacta agatttaccg tacgaatatc cacgttgcca
    23521 tacagcgtca ggccgttatc ctggcggctt tgataccacc agtagcctcc ggcaaccacg
    23581 gcggcaagta ccactaccgc caatccgatc acgacaggtt ttttcatcac tacaaactcc
    23641 tttgcgataa tccttgcaaa atcaggtcga tatgacaggt caccgtctgg ttgatcagtt
    23701 cggtcttttc ttcatcgaac gcggtccagc cggtacgtaa cagaattgtt tctttgccaa
    23761 gacggaacgc cagaatctca ccaatcaacg catgagtatg gaggatcatg cgggtatcgt
    23821 tggcgtcgca gccggtccag gcggcaatca ggcgtgtcag gtggctgtgt agcgggctaa
    23881 tcacctgttc gtgcaccagg tgataggctg ccgtgggaga gagctgctca cgggagataa
    23941 acttgctgag gttgacggtg tcatcctggg tgagcagctt aatcatgttc ctgcaggcgc
    24001 gaaggatcag ttcacggatg gctgcgcgat caggctgtgg ttgtgcgaac aagcgttcgg
    24061 cctcttcggc gtgcggacgg aactgctcgc caataaaatc ggcaatccac tgggcgcagg
    24121 cgaggtacaa atcttctttc gaaccgaagt agtaggtgat ggcagcgata ttctgcccgg
    24181 cctgggcggc tatctcgcgg gtggtggcgt tcattccata ttcaccaaac tgcgccagtg
    24241 cggcagcaat cagctgtttt ttcgcctgtt cacccttgat tgtcatggca ggattattca
    24301 tcgcacagtc cattcttaat caaatgattg attaagatta tgactccata tgggagttgt
    24361 ccagtatggc taagaatttt agctacgcca gtcacaggga taatttatgc gctgcgtcac
    24421 aaaaactgct acactccgct ccctcatgac attgtggttt ttgtcatttt ccttttcagt
    24481 atctccctga aaactacacc ggtaacggtc ggggcggttc ggagtagtta tgtctttcga
    24541 ttctttgggt ttaagccctg atatcctgcg cgccgttgcc gagcagggtt accgtgaacc
    24601 cacccctatt cagcagcagg cgatccctgc ggtgctggaa ggccgcgacc tgatggctag
    24661 cgcccagacc ggtaccggta aaacagcggg ctttacgctg ccgctgttgc aacacctgat
    24721 cactcgccag ccgcacgcca aagggcgtcg tccggtacgt gcgctcattc ttaccccgac
    24781 ccgtgaactg gctgcgcaga ttggcgaaaa cgtccgtgat tacagcaaat atttgaacat
    24841 tcgttcgctg gtggtgtttg gcggtgtcag cattaacccg caaatgatga agctgcgcgg
    24901 cggcgttgat gttctggtgg caacaccggg acgtttgctg gacctggaac atcaaaatgc
    24961 agtgaagctg gatcaggttg aaatcctcgt cctcgatgaa gctgaccgca tgctcgacat
    25021 gggctttatc cacgatatcc gtcgcgtgtt aacaaaactg ccagcgaaac gccagaacct
    25081 gctgttctct gcgaccttct ctgacgatat taaagccctg gcggaaaaac tgttgcacaa
    25141 cccgctggaa atcgaagtgg cacgccgcaa taccgcgtct gatcaggtga cccagcacgt
    25201 tcactttgtt gataagaaac gcaaacgcga attgctgtcg cacatgattg gtaaagggaa
    25261 ctggcagcag gtgctggtgt ttacccgtac caaacacggc gctaaccatc tggctgagca
    25321 gctcaataaa gatggcatcc gtagtgcggc gatccacggg aataaatcgc aaggtgcgcg
    25381 tacccgtgcg ctggctgatt ttaaatcggg tgacattcgc gtactggtgg cgaccgatat
    25441 cgctgcgcgc ggtctggata tcgaagagtt gccgcacgtc gtcaactatg aactgccaaa
    25501 cgtaccggaa gattatgtcc accgtatcgg gcgtaccggt cgtgcggctg ctaccggtga
    25561 agcgttgtcg ctggtgtgtg ttgatgaaca caaactgctg cgtgatatcg aaaaactgct
    25621 gaaaaaagag atcccgcgca ttgcgattcc gggctatgag ccggacccgt caatcaaagc
    25681 cgaaccgatc cagaacggtc gccagcaacg tggcggcggc ggtcgtgggc aaggtggtgg
    25741 tcgcggtcaa cagcaaccac gccgtgggga aggtggcgca aaatctgcaa gcgcgaaacc
    25801 tgcagaaaaa ccgtctcgcc gcctcggcga tgccaaaccg gcaggcgaac aacaacgtcg
    25861 ccgccgtccg cgtaaaccta ccgctgcgca gtaatctttt atgccgggct atgcccggca
    25921 tcaggctgat gaacaaacgc aaaactgcct gatgcgctac gcttatcagg cctacgtgaa
    25981 ctctgcaata tattgaattt gcatgctttt gtaggccgga taaggcgttt acgccgcatc
    26041 cggcatttca caacaagcac ttgtcagcaa tttgagaaca cgggaaaaaa tttatctgtt
    26101 ttaccgccca taagccaccg agacgttact tctctatagc caattgttcg cgcaactcca
    26161 ttaaaaggta gcccagtcga ttcttgccct taccattacc accgtctccc cagtaagcat
    26221 cgttttctgt atgctcaacc agttttgcgg gcgcggttgc cagcaagagc gcacgcagtt
    26281 ctggatgctg ttcgaattta gcgcgaagtg cttttcgcat cacctgttct ttgaccgact
    26341 cccagttttt acgcagaggc ttagaacgat cgcgccccat gcgtgcggcg accatagggg
    26401 aagaaacccg acggatctct tcgcggtatt tttcatcaag gaatttttgt gcctgaaaat
    26461 agtgttctga ggtgggccag gttttcccgt caaccttgat gggccaggcg gcaaagttag
    26521 aaaaatcacc gtagtcatcg ctggtgctgt agaaatttat gatggtgtct tgcatgacgt
    26581 gttggatcct ttgtgctcga acgggcatta aaccgcatta tgttggtggt tattgcgagc
    26641 cgctttccag aaacagaaaa accattaccc ctgaaaaccg aaaaatgcca caatattggc
    26701 tgtttataca gtatttcagg ttttctcatg gcattaaccg ccgcgcttaa agcgcaaatt
    26761 gccgcctggt ataaggcgct tcaggaacag atccccgact ttattccccg tgcgccgcag
    26821 cggcagatga ttgcggacgt cgccaaaacg ctggccggag aagaagggcg gcatctggcg
    26881 attgaagccc ccaccggcgt tgggaaaacg ctctcctatt tgatccccgg catcgccatt
    26941 gcccgcgaag agcaaaaaac gctggtggtg agtaccgcca acgtggcgtt gcaggatcag
    27001 atttacagca aagatttacc gctgctgaaa aagatcattc ccgatcttaa attcactgcc
    27061 gcttttgggc gtgggcgcta cgtttgcccg cgtaatctga cggcgctcgc cagcactgag
    27121 cccacgcaac aggatctgct ggcgtttctt gacgacgaac tgacgccaaa taatcaggaa
    27181 gagcaaaaac gttgtgcgaa gctgaagggc gatctcgaca cttataaatg ggatggtctg
    27241 cgcgatcata ctgatatcgc tatagatgac gatctctggc gtcgtttaag taccgacaaa
    27301 gccagctgcc tcaaccgcaa ctgttactac tatcgtgaat gcccgttttt tgttgctcgt
    27361 cgggagattc aggaagcgga agtggtggtg gcaaaccatg cgctggtgat ggcggcgatg
    27421 gaaagcgaag ccgtactacc tgacccgaaa aatctgctgc tggtgctgga cgaaggtcat
    27481 cacctgccag atgtggcccg ggatgcgctg gagatgagtg ccgaaatcac cgcgccctgg
    27541 tatcgactac agctggactt gttcacgaaa ctggtcgcta cctgcatgga gcagtttcgc
    27601 ccgaagacca tcccaccgct ggcgatccct gaacgtttga atgcgcattg tgaagagttg
    27661 tatgagctta tcgcctcgtt aaacaacatt ctcaatctct acatgcctgc cgggcaggag
    27721 gcagagcacc gttttgcgat gggcgaactg cctgatgaag tgctggagat ctgccagcgg
    27781 ctggcaaaac tcaccgagat gctgcgtggt ctggcggagt tatttcttaa cgatttaagt
    27841 gagaaaaccg gcagccacga tattgtgcgt ctgcatcggt tgattttgca gatgaaccgc
    27901 gcgttgggga tgttcgaggc gcaaagcaaa ctctggcggc tggcgtctct ggcgcaatct
    27961 tccggtgcgc cggtgaccaa atgggcgacg cgggaagagc gcgaagggca gctgcatctc
    28021 tggtttcact gcgtggggat acgtgtcagc gatcagctgg aaaggctgct gtggcgcagt
    28081 attccgcaca ttattgttac ctccgcaacc ttgcgttcgc tgaatagttt ttcgcgtttg
    28141 caggagatga gtggtctgaa agagaaagcg ggcgaccgtt ttgtggcgct ggattccccc
    28201 tttaaccact gcgaacaggg caaaattgtt attccccgga tgcgcgttga gccttccatc
    28261 gacaacgaag agcagcatat tgccgaaatg gcggcctttt tccgtaagca ggtggagagc
    28321 aaaaaacatc tcggtatgtt ggtactgttt gccagcggac gggcgatgca gcgctttctc
    28381 gactatgtga cggatttacg cctgatgctg ctggtgcagg gcgatcagcc gcgttatcgc
    28441 ttagttgaac tgcaccgcaa acgcgttgcc aacggtgagc gtagtgtgct ggtgggctta
    28501 cagtcatttg ccgaagggct tgatttgaaa ggtgatctgc tcagccaggt gcatatccac
    28561 aaaatcgctt ttccgcccat cgacagcccg gtggtgatca ccgaagggga atggctgaaa
    28621 agcctcaacc gctatccgtt tgaggtgcaa agcctgccga gcgcctcgtt taacctgatt
    28681 cagcaggttg ggcgactgat tcgaagccac ggttgctggg gcgaagtggt tatctacgac
    28741 aaacgcttgc tgaccaaaaa ttatggcaag cgactactgg atgcattacc ggtatttccg
    28801 atagagcaac cggaagtccc tgaaggtata gttaaaaaga aagaaaaaac gaaatcccca
    28861 cgccgtcggc ggcgttaatg atgtgagtca ggtaaggagt cgtaaatgga ctatcgcaaa
    28921 atcattaaag agatcgggcg cgggaaaaac cacgcgcgcg atttagaccg ggatactgcg
    28981 cgcggtctgt atgcccatat gctcaatggt gaagtccctg accttgagtt gggcggcgta
    29041 ttgattgcgc tacgtatcaa aggggaaggg gaagcagaga tgctcggctt ttacgaagcc
    29101 atgcaaaatc acaccatcaa gctgacgccg ccagcaggca agccgatgcc gattgtcatc
    29161 cccagttaca acggcgcgcg taaacaggcc aacctgacgc cgttgttggc gattctcctg
    29221 cacaaactcg gttttcctgt ggtggttcac ggggttagcg aagatccaac ccgcgtgctg
    29281 actgaaacca tttttgaatt gatgggtatt acgccaacgt tgcacggcgg gcaggcgcag
    29341 gcgaagctcg acgaacatca accggtgttt atgccagtcg gcgcgttttg cccgccgctg
    29401 gaaaaacaac tggcgatgcg ctggcggatg ggcgtgcgta acagtgcaca taccctggcg
    29461 aaactggcga cgccatttgc cgaaggtgag gcgctgcgtc tttccagcgt ttcgcatccg
    29521 gaatacattg gacgcgtcgc gaagttcttt agcgatatcg gcgggcgggc gctactaatg
    29581 catggtactg aaggtgaagt gtatgctaat ccgcagcgct gcccgcagat caatctcatt
    29641 gaccgtgaag ggatgcgggt gctgtatgaa aaacaggacc ctgctggtag cgagttactg
    29701 ccacaagcaa aagatccgga aaccacggcg cagtggattg agcgttgcct tgctggcagc
    29761 gaaccgattc ccgaatcgct gaaaatccag atggcttgct gcctggtggc tacgggtgaa
    29821 gcggcaacta tcagcgacgg cctggcgcgc gttaatcagg cattttaatt cttttctcag
    29881 ccggatgagc catgtcatcc ggcttttacc ccaccgcaat atgaaattcc tgcatcttta
    29941 ttgaccttcc cgcgcccggc gtgcagcata aaaaaacaac aaacacataa cataaacagg
    30001 agttaaccat ggaaagtggt catcgctttg atgctcagac gctgcacagt tttattcagg
    30061 ctgtatttcg tcagatgggt agcgaggaac aagaagcgaa attagtggcc gatcatttaa
    30121 tcgcggcaaa cctggcaggg catgattctc atggtattgg catgatccca agctatgtgc
    30181 gttcctggag tcaggggcat ctgcaaatta accatcatgc caaaatcgtt aaagaggcgg
    30241 gggcggcagt cacgctcgat ggcgatcgcg cattcggtca ggtcgcggca cacgaagcga
    30301 tggcgctggg gattgagaaa gcgcatcagc acggtattgc tgccgtggcg ctacataact
    30361 cgcatcatat cggccgtatc ggttactggg cggagcagtg tgcagcggcg gggtttgtct
    30421 ctatccactt tgttagcgtg gtcggtattc caatggtcgc accgttccac ggtcgcgaca
    30481 gccgctttgg caccaatccg ttctgtgtgg ttttccctcg taaagataat ttcccgctgt
    30541 tgcttgatta cgccaccagc gccattgcat ttggcaaaac ccgcgtcgcc tggcataaag
    30601 gcgtccccgt gccgccaggt tgcctgattg acgttaacgg cgtgccgacg accaatccgg
    30661 cggtaatgca ggagtcgccg ttgggttcgc tgttgacctt tgccgaacat aaaggctacg
    30721 cccttgcagc gatgtgtgaa attcttggcg gggcgctttc cggcggtaaa acgacgcatc
    30781 aggaaacgtt acaaaccagt cccgatgcca ttcttaactg catgaccact atcatcatca
    30841 acccggaact cttcggcgcg ccggattgta gcgcgcagac cgaagccttt gccgagtggg
    30901 tgaaagcctc gccgcatgat gatgataagc cgattttgct accgggcgag tgggaagtga
    30961 acacgcgtcg cgaacggcag gagcagggga ttccattgga tgcgggaagc tggcaggcca
    31021 tttgtgatgc ggcgcggcag attggtatgt cggaagagac gttgcaggct ttctgtcagc
    31081 agttagccag ctaaaaaaaa gcccgtccag tggcggacgg gcaaacaagg gtaacatagg
    31141 atcaatgagg gttagagcat atgcgtctgt cggcaaacag acagggaaat acttgtgctg
    31201 gacgtagcgt aaacgcctga tccgtccaac ggttcggatt ttgtaggcct gataagacgc
    31261 ggtagcgtcg catcaggcat ctgttgccgg atgcggcgta aacgccttat ccttcctacg
    31321 aattacttat aaattaccgc agtaccgctt aatttattgt tgttggtggc ggaagtgatg
    31381 ctgtatccac tggcaccggc tgccgcggct ttctcagcca gtttcgcttc cagggcatcg
    31441 agggtggatg cgccatcggc agaaaccacg ccgattttat tcatgttctg tgcctgggat
    31501 gccgttaccg gttccgcggc aaacacgcca aatgacagag ttgaaagagc catagcagca
    31561 acaacagtat tgatagtttt cataattaat ctctcgcagg tgatttttgt ataagtgacg
    31621 ttgtttcgtc gatgtgatga gtatcacgtt tttttacgag agataaaatc gaagagaatt
    31681 gaccgccttg ttcaaataaa ttgattgata tctaacatac tgataaacca tttatttgtt
    31741 gtacttatgg acttgtttta tgcagcgtgg cagtcacgac agcgttaaag gcacggaatg
    31801 ccacgcaaaa tacaaattat actcgctata catctcgcca gttgtagtta acgtaactgg
    31861 ctgtctttcg aacctctgcg attatatcct gtatacgctg gtttttgtaa atctttctcc
    31921 tgctgacaat gaatgcataa gcgcacgcca ggaatggctt cccgacgggc ttgcgggatg
    31981 ggggcaccgc actcttcaca ttcatccagg ctttcgccac gcggaatttc accccgagcg
    32041 cgggcaatcg catcttcaat tgtactgttg atctgttcgt tgacggcgtc atcgttagcc
    32101 caaccggatg ccatatcgtc ctccccatat caatgcttgt acagttaagt gtagctaatc
    32161 cagggacgaa cttgggcagt tcaagcatca gatctccgac cattcccgca gcagattatg
    32221 ataaagatta agcagcgaca ggatctcttc attttcacca tagcggcttt tcagcgactg
    32281 aatattgttg tccagttcaa acagcatggc gcgcttttta tcatcacgga tcatcgactg
    32341 gatccacata aatgatgcca ctcgtacgcc gcgggttacg ggtgtcacgc aatgcaggct
    32401 gctggaggga tacaacacga gatcgcctgc cgggagtttt acccgatgtt gtccgaaggt
    32461 gtcattaacg accagttcgc cgccgtcgta gctttgtgga tcgcttaaaa acagcgtggc
    32521 agaaaggtca gtacgcatcc agccgttttg tggatggctg cgtactgcgc catccacatg
    32581 gaaaccatag gtttcattgt tctgatagcg attaaacagc ggcgtggaaa gggtacgcgg
    32641 caaggccgcg gcaaagaata aagcatgttg gttaaccgcg ttcagcacct cattttgcag
    32701 ggcggcgtat aacgtgctgc gggtgtcgac ctgttgattg ttcttaactt gcgcaccttg
    32761 tgcgccggtg gtgacgcgtc catccaccca ttcggcttgt tccagttgtt cgcgaaaccg
    32821 ggcgacgtcc tgtggcgata acacgccggg aatgtggtac atcatacaag ttctccaaaa
    32881 agtggggcct gcgccccaca tctgaatcag aaatgcatat tggctgtgag caagaaggtt
    32941 cttggctcgc ccgggtgata acggtagccg ctcttgttga ttgaggcgac gtaatcggta
    33001 tcaaacaggt tgtaaacgtt tagctggaag tcgagattgc gattaacccg ataccccagt
    33061 ttggcatcgg cgacccagta accttcggta aacgctggcg ttcccaccgc gccgtctgaa
    33121 cctttatgca tactgccgat atagcgtgcg cccgcgccaa cagagatatc atctgttgcc
    33181 tgatactggc tccataaggt gaaggcgtgc tccggggtat acggcagcga tgaggaacca
    33241 tcctgggcaa catctttgcc gtttttgatg gttgcttttt gctgggtata gccgccaatc
    33301 acctgccacg cgggcgtgat attcccggcc acggatatct catagccttc gacacgtttc
    33361 ttaccgtatt gcgagtaagt tccgtcatca ttttgctcaa cttcattttc gatatcagta
    33421 cggaatagcg cggcggtgag caacaggcgt ttatccagaa cctgccattt ggtgccaatc
    33481 tcgctggtgt tggctttttg cggtttaaaa tcggtgcggt tggcactgtt accgctgcca
    33541 gactgcgcaa gggcgaagtt gttgccgccc ggaggctgct gggaaacggc atagttaata
    33601 tagacattac cgttttccgt caggtgatac agcgccccgg ctttccagtt caccagattg
    33661 cccgacttgg cggtgtcgac ggtggtgacc ggagaacctt ttgccacacc agctgggcag
    33721 gtgatggcac cgcgtccgct gccgccgcag gcggtggcac tgtcatattc agtatgataa
    33781 ttatccagac ggatcccgcc gttcagctca aaatcacggg tgatttgcag cgtatcgaag
    33841 gcgtaaattg cgaaggtatc cgtctgacca ttggcgtttg cgccgttgcg cgtcaggccg
    33901 ccgggatgaa tgctgctgtc aggatgataa atatttaccg cgggtaacgt caccggatta
    33961 acgccgtagt tagtctgcgt ttcacgggta aattccacgc cggtactgac atcatgaccg
    34021 atagaaccgg tatagaacgt cgaggtcagg ttggtctggt tggtgagaat tttattactc
    34081 acatctttgg tattcgccgt gcgtgaccag gtccagctat tcacatcgct ggtgggctga
    34141 gtaatattcg acgccccgcc cataatcgcc gtcatcaggt aatcctgctt tacgcgcgac
    34201 caacgggtag tattgcgaat ggtggtgtta tcgttgatgt cgtgctcaaa acgcatggtg
    34261 gcggtgtcgg tggtcgaatc gtcgtaatcg gaatccgtgc cgtaaaagtt atgagtatca
    34321 acttttccgg aatgattcag agccgctgtt cccgcagatg gggcagaata acccggcaaa
    34381 ccgatggtcg gaatgccgcc gtctggcgtg ttgtgctggg tgacatgcag ataattaaga
    34441 tacaaacgat tcgctgtacc aaggccaaaa gcgatagaag gggcgacgcc gtaacgctca
    34501 tttttgactt tgtcgcgtcc ggcatcgtgc gttttttcgc ccatcacatt caggcgcacc
    34561 gcagtggtat caccaatgac ctgattgacg tccagcgtgc cgcggcggaa ccaggcgctg
    34621 ccaatactgg cggaggcgtc aatgccggaa tcattgcgcg gctgcttgct gatcatattg
    34681 atcgagcccg tcggcgcgct gcgcccgtag tcggtgccgg aaggcccttt aatcacttcg
    34741 acctgctcag tattgaaggt gtcgcgcgag acgctgccga tatcgcgaat gccatcaata
    34801 taaatactgt tagaggtatc agcaccgcgc atataaatgg cgtcgccagt ggtggagtta
    34861 ccgttctcac ccgcaaaaaa cgcacccacg ccggggacgt ttttgagcgc gtcggtaagg
    34921 ttggttgcgc cctgatcttt aatcacttgt tcagaaatca ccgtcatcgt gcgggtagta
    34981 tccgctaccg gacgcgagaa tttcggatcg gcagattgtt gtggcgcata aagcgaaggc
    35041 gttgatgctt cgacaaccag cgtgtcatcc gcgttagttt gcccttcggc ggcgagtgcc
    35101 tgagccacag gcgtgatgcc aatacaaaga ccggcaaaga acgtgagcga atgaaattgt
    35161 ctggcaggga aattgcgatt gttttccatt ttgcaggtga ctttttttat atgttgaaat
    35221 tttcactgcc acgagaaagc ctctctgcgg atgcgatgcc actgttaatc tcgtgatagt
    35281 gttcgtgcaa gtgataataa ttttgataag cattatcact tggcgcgatt ttctatcacc
    35341 cattgcgcga aaaagaaata catttattta cattgcgttc atatttgatg ttttttgatt
    35401 acaaaacagg cgaaaactgc atccagaggc gaatgcagtt acgttggtgg ggttatttgt
    35461 agatggttgc agtaccgaac atctggtcat ttccgcctgc ggaattaatg acataacctt
    35521 tcgcgccttg ctcgcgcgct ttttctgcca gtttatcctc cagatcgctt aggtttgatg
    35581 cgccagttgc cgaaacggta ccggcgggcc gtagctgacc gctgtccagg ttactcatcg
    35641 gttgcgcggc ataagccgtg agagagattc cgctcaggac ggtggcaatc agtagtgtga
    35701 ggcacttttt cataatgaca tcctcataaa tacaacgggt agtgcctgat aagtgtaggt
    35761 cgcctgggcg atgaaaatga cgcaaaaaat tgacagagat gtgcttattt tttgaacgat
    35821 atatttttac aaaataagac aaatcaatga catgcataat gctgattttt atgatgaatt
    35881 gccataaacc atagccatgt taaggttttg gggaatgata aacgcagcca gatatttacc
    35941 ctgtcgcgtt atgcgggtat cttacgccgc tgcttaaagg agaatgctat gtccgcccag
    36001 aaaccggggt tgcatccgcg caaccgtcat cacagccgct acgatctcgc cacgctttgt
    36061 caggtcaatc ctgaactcag gcaattcctc acgcttacac ccgcagggga gcaaagcgta
    36121 gactttgcca atccgctggc ggtgaaggcg ctcaataagg cattgctggc ccatttttac
    36181 gccgtagcga actgggatat cccggacggt tttctctgcc cgccagtacc gggccgggcg
    36241 gattatattc atcaccttgc cgatttactg gcagaagcaa gcggaacaat tccagctaat
    36301 gccagcattc tggatatcgg cgttggtgcg aactgtattt atccgctgat tggcgtacat
    36361 gaatatggct ggcgttttac cggtagtgaa accagcagtc aggcgttaag tagtgcgcag
    36421 gcgatcatca gtgctaatcc ggggcttaac cgcgccattc gtctgcgtcg gcaaaaagag
    36481 agtggggcga tttttaacgg catcatccat aaaaacgagc aatacgacgc gaccttgtgt
    36541 aacccgccat tccacgattc cgccgctgcg gcacgggcag gtagtgagcg taaacgccgt
    36601 aacctggggc tgaacaaaga cgatgcactg aactttggcg gccagcaaca ggagttgtgg
    36661 tgtgaaggtg gtgaagtcgc ctttatcaaa aagatgattg aagagagcaa aggcttcgcg
    36721 aagcaggtga tgtggtttac ctcgctggtt tctcgtggtg aaaacttacc gccgttgtat
    36781 cgtgctctga cggacgtggg cgcggtgaag gtggttaaaa aagagatggc ccaggggcaa
    36841 aagcagagtc gctttattgc ctggaccttt atgaacgacg agcagcgccg ccgttttgtt
    36901 aatcgccaac gttaaagcgt tggctccccc ggcggcagcg gttcagccgg ggccgcgccc
    36961 ggagcaggca gcacctgata agtctgcact ggcgcgcgaa cacctgccag gtcgaaatgc
    37021 tttttcacct ggctgtcgag ggcaaagcgg accgtccact gtttgagtgg cagcgtggtg
    37081 aacgaaacac gcagtgtaaa cgcggtattg cttaagccga caatcccggc aaagtttggt
    37141 tcaccaataa ccagcccgcg aatttcttcg ttttccatca attccgctac cgcatctttc
    37201 agtgcctgat tggctttatc agcatcttca tggcgatcaa catcgtagtt tgccaccacc
    37261 gaaccaatgc cgcggacgaa gttagcaaag gtggttatcg aagaccaagg aatgatgtga
    37321 tacgccccgg tatcctgacg cacgcccacg gagcgaatcg acatccgttc cacagtgccg
    37381 gtcaacggcc cgatagtaac caaatctcca gtgttcatgc cgttttcaaa ctgaataaat
    37441 accccggtga taatatcttt caccagcgtt tgcgaaccaa acgagatagc cagacctaat
    37501 gccccagcac ctgccagcaa tggcgcgata ttgacgccga tttccgacaa cacaatcatg
    37561 atggtgatgg tactgataat caccgccagc gcgttacgga acagcgtcag cagggtacgc
    37621 gtacgggcgc tgggtagcgg gcggccatga atatccgaag ccagccggtt ttcgatcaaa
    37681 ctggcgagca ctgtccagcc aaccgccgag aagaaaagaa tgagtgcgat gcggatcagg
    37741 atatctacgg ttttctgccc cgcgccgttt tgcagccagt tccagaaatc gaacaatccc
    37801 catgcgctca acagcaacat taccgccacg cagacggtca gaatacgcgc cgttttcagc
    37861 gccgccgaaa gccagccatt cagccgtttt tgtagctccg gatagttacg ctgagtatgt
    37921 ggcgagaggg tgatggtttt cgccagccag cgggaaaaca taccggaaac aaacgctgcg
    37981 ataccaataa tcgccaggct gcgcaccgtt gcacccatca taaatttcag gctgttgccc
    38041 ggatcgaaca acgaaaagaa aaacagcacg ataaaatagg cgcttgccag ccagtgccac
    38101 accagcgcaa aggcgcggat aaacaggctg aaaaaggcca gcgaatgctc cgcaaagttg
    38161 agcaaatgtt gggtaatctc ttttttattg cgaaagatca ggtacaacgc ccagacggtc
    38221 atgcacagca taatgatgac gttcgccagc gcacctatct gtacattcac ctgattagag
    38281 ataatcggca cggccacaat caggccataa cctatcaaac tgcttaacca gctcaggcga
    38341 cgactccagt aacgggcgct ctcgtcctga atcgtgaacg ggcgcagttc agccacgttt
    38401 gggcaaaaaa tcaggcgtag tacggctttg aaaaattcaa tcagggcaaa ggcgttgaga
    38461 aacaaacttt gttggaaagc gatggtgcga ctgcccgcat tcaggttgtc gcttaatacc
    38521 tggccgacaa acaatgtcag tgccagtaac agtaggtcga taataaacgc cccgataatc
    38581 atcgccggaa gctgcagcca gttgctgcgt tcgcgatttt tttgccgcgc ccactggccc
    38641 attttgcgat acagcggcag tgcgcacaga cgaatcagcc agtaaaaacc aaacactaat
    38701 accgctaaca ttgaaaaatg ggtcaacgca ttgctgaagg tttgtggatt aaacggctta
    38761 tgcggggagc cggtgatatt gcgataaagt tgtccgaagc gggcggaaag ggcttcacca
    38821 taatggcggc tgacttcggt gaccttttgc agcacggttt gctcttcaac cagcgtcggc
    38881 ggcacgatct tcgggaccgg ttccgcaggg ggcgtcgcgg cgacagtacg caactggtcg
    38941 atcaattctt tacgcgaggt gtcgttatcc agcacatccg ccagtgcgcc ataggccgct
    39001 tttttttgtt cgatatccgg ttccggggcc ggttcagtcg ttgagtccgt tgtcgttgtg
    39061 gttgtaacgc cgggtatgga taccgcgtgg gcaggtgcgc ccagcaggca gaagaggatg
    39121 aacaggatcc accgcatgac tcctccagtg agaaaacaga gcaaaaagat aagtatagat
    39181 gctgggggag gggcgatttt aaatgagagg aatctggtgt gcctcccttt cgggtgaaag
    39241 ggaggcagag aagttaagag acgtgctgca aaaattcctg caagcgctgg ctcggcgggt
    39301 tcttgatcaa tacctgcgga tcgccatctt ccgcaatccg gcctttgtcg ataaagatca
    39361 gccgcgaagc tactttctcg gcaaaaccga tttcgtgggt cacgatcacc atcgtcatcc
    39421 cttcttcagc cagatcctgc ataaccttca gcacttcatg gcgcagttcc gggtcaagag
    39481 cggaagtcgg ttcatcaaac agcatcattt tcggcttcac cgccagcgcg cgggcaatcg
    39541 ccacacgctg ctgttgacca ccagaaagtt cggaagggta gtgatgtgca cgttctgcca
    39601 gaccgacttt cgccagcagc tcacgcgcca gtttttccgc ctcttctttg ttcgcgccac
    39661 gcacgcgtag cggaccaaac atgacgtttt ccagcgccgt cagatgcggg aagaggtaaa
    39721 actgctggaa caccatacct gcttcctggc gaatcaggcg ctcgtcaact ttcggatcgt
    39781 taaccttcag gccatcgaca atcagatcgc cggaggtgat ttcttccagt ttgttgatgc
    39841 agcgcagcag ggtcgattta ccggaaccgg acggcccgat aatcaccacg acttcgccct
    39901 gggcaatgtt caaatcgata ttgtgcagca cctgggttgg gccaaagtgc ttggagacgt
    39961 ttttaaattc aatcacagga ttttcatcct tctttccaga cgacgcagaa taaagctcag
    40021 caccagggta ataatcagat agaacaccgc cacggcgctc cagatctcaa gggcgcggaa
    40081 gttaccggca ataatttctt gcccctgacg ggtcagttcc gccacgccga tcacaataaa
    40141 cagcgaggtg tctttaatgc tgatgatcca ctggttaccc agcggcggca gcatacgacg
    40201 cagtgccagc ggtaaaatga cgtagcgaat ggtttcccaa cgtgaaagac cgagcgccag
    40261 tcctgcttca cgaaaacctt tgtggataga cagcaccgca ccacgcgtga tttccgcaat
    40321 gtacgcgccg gagttgatca tgatggtgac caccgccgca gtaaatgggt cgatgcgtaa
    40381 gtcgttaaac gccatcggca gggcgaaata gataaacatc acctggacga cgataggtgt
    40441 gccgcggatc acttcaataa agaccagcgc gacgtggttg gctatccaac caccgaaggt
    40501 gcgtgcaaaa cctgccagca atccgattac cagaccgcct gccagaccga ggaccgaaat
    40561 ccacagggtc attttggcac cttcaatcag aagcggaatg gcaggccaga tggcactcca
    40621 gtcaaactgc atatgttgtt cctgttaccg tggtgtaaat aatcaaattc agggtaatta
    40681 atggccccgg agcgggtttg cgcccctcac cctaatcctc tccccatagg ggagagggaa
    40741 ctgccagtgc gttttacagg tgtagcgtta ttatttcggt tcagtaccga accatttttt
    40801 gtagatttcg ttgtaagttc cgttctcgcg cagggttttc aacgcgccgt tgactttgtc
    40861 acgcagctcg tcgctacctt tcgggaacgc aataccgtat tgctgcgctt ccagagagtc
    40921 acctaccgct ttgaactgac cgttaccggc ggttttgatg aagtacagaa tgtttggcgt
    40981 atcgtgcaga acggcgtctg cgcggttggt gcccagttcc atataggcgt tatcgatgtt
    41041 cgggaactga cgcagatctt tagttttgat gtttgctttc gcgtaatcaa cggagccagt
    41101 accgctcttc acagcaacca ctttcccgtc gagatctttc acgcttttca catcgttatt
    41161 gttagctttc accatcacta acaggccgct tttgtagtag ccgtcagaga aatcgatcgc
    41221 ttttttacgc tcgtcggtga tggtaatgcc cgccagcgcc agatcgacgt ttttggtttg
    41281 cagtgccgga atgatcccac tgaaatccat cggcttcagt tcgtaatcca gcttcagctc
    41341 tttagcgatg gcagcccaca gatcaacgtc aaagcccaca tatttatcgc cctgtttaaa
    41401 ttcaaacgga acgaaggcgg tatccgtcgc gacaactaat tttttatccg cggcatgaga
    41461 agaaaccgca aaagccaggg tcagtgcagc cagtgaaact tttaatacag acttcatagc
    41521 atttcctttt ttctatccac gggacgatcc cctgcgtgac attcacatat atgaaaaaat
    41581 cgtgccagtt ttgcaactcc ttgatttttc gagatgcggc aaaaacgtga tgcacgattt
    41641 atagggcaat accctgaaga tgcaccattc tggggcacca atctggtgcg ctaaaattgt
    41701 gcactcaaca cagtgattat ttagcgtaaa acctgatgaa aaaacaatct ttatgtaacg
    41761 attgtgtgat gatgtggata caaaaaattt acttaatcag ctggagatag cagatggatg
    41821 cactaaataa gtgcgttgag gtgggctgca aaacaaaacg gcctcctgtc aggaagccgc
    41881 ttttatcggg tactaaagtt ctgcaccatc agcgatggat ttattcgatg ttagactcga
    41941 taaaccacag gaatttatcc aggtcgcgag acgcggcggt caggatatct gcggtgtcgt
    42001 catctttcgc ttcgccaatc gctttgcgta cgtcattagc gacgattgcg taacggtcag
    42061 ccagttcttt caggtgatcc tgaacgttgt ggatgtccag cgggtaactt ttcagcgggg
    42121 ttttgctgtt gataacttga gtggtcccca gagctacacc gcccagctgc actgcacgtt
    42181 ctgccatggt atccagatga tcgatcagtg cggtgcggaa gccatccagc atttcatgta
    42241 cggcaatgaa gttagcgccg cgcatgttcc agtgcgcttg tttggtaatc aaagaaagat
    42301 caataaactg gataacctgg cgattcagca actctactgt tgcttttttc tcgctgtcgg
    42361 agacatcgtt gcgggtataa agcagattgg tcgcttttga tttaactaat ttagcggtac
    42421 tcataatttc atatcctctt gatgttatgt cccagtaatt aacgagacta agtatagcac
    42481 cggctatgtg ttccgctatt ctggctgttc ctatcacact aatagtggta acaagcgtga
    42541 aaaacaaaac taataaagat tcaatgagtt agatatattg ataagaacaa ttcttattta
    42601 tctgctcgcc aggaattttc ggaataaata tgcttttgca taattcgata tataaagacg
    42661 gtgtagagga aaagtagcga gaaattctgc atggttatgc ataaccatgc agaaatgtaa
    42721 atttaattaa tgtctaattc ttttattttg ctctctttgc gtactgtcag cgtagacccc
    42781 attgaagcgg cgatgatagc gccgagcgcc agcagctgta tgggtgtcag tgtttctccg
    42841 aggaaaatca tcccggaaac ggcagccagc gccggttcca tgctcatcag cgtaccaaat
    42901 gtccgtgttg gcaaacgggt gagggcaatc atttccagcg aataaggcag agcggtcgag
    42961 agaatagcga cagccagacc caatggaata accgaccagt gccagagtgc ttcaccagcc
    43021 tgaagcgctc caattggcac gaaaattaac gctgcaatca acgaaccaat tgccaccgtc
    43081 gcagggccat gttccgctcc tgcgcgttgc ccacttaaaa tgtaaatagc ccaacaagcc
    43141 ccggccccca gtgccagcgc acagccggtt aaatcgacat gggaaacgtc ttgccccagc
    43201 ggtagcagga accacagacc aagaaccgcc agcacaaccc agacgaaatc taccgggcga
    43261 cgagaagaga acagcgccac cgccagtggt ccggtgaact ccagcgccac cgcaataccc
    43321 agcggtactg tctgaataga aagataaaaa agataattca tcccacccag cgaaacgccg
    43381 taaaacaaca gcggtaaccg ttgctctttg gcaaagcgca gtcgccatgg cttaaagaac
    43441 gcgatgagga tcagcgttcc taatgccaga cgcagcgcag tgacacccgg tgcgcccacc
    43501 agaggaaaaa gtgacttagc taacgaggct ccaccctgaa tagacgccat ggcaacgagc
    43561 aatatgatta ttggtaacca gaccggcatt ttacgtaatg aaccaggcat cctttctccc
    43621 acaaatatct agacttaagt aaagcgtgga gtgtactgga tatacccaat gctggttgag
    43681 catttgttga aaaaattttc ccccgttttg actaaaatgc gccaggattg atggaatcat
    43741 tagtctggtg attaggaata atctggatga atgacaggga aaacatgcgt aatacttacg
    43801 cagttctctg aaaaagtgat ttaaatttag atggatagcg gtgtatggaa acgttctgtt
    43861 acatgaaatg gcccgttaga catcacaaat cgcgaagagt ttcccattaa tttttgatat
    43921 atttaaaact taggacttat ttgaatcaca tttgaggtgg ttatgaaaaa aattgcatgt
    43981 ctttcagcac tggccgcagt tctggctttc accgcaggta cttccgtagc tgcgacttct
    44041 accgtaactg gcggttacgc acagagcgac gctcagggcc aaatgaacaa aatgggcggt
    44101 ttcaacctga aataccgcta tgaagaagac aacagcccgc tgggtgtgat cggttctttc
    44161 acttacaccg agaaaagccg tactgcaagc tctggtgact acaacaaaaa ccagtactac
    44221 ggcatcactg ctggtccggc ttaccgcatt aacgactggg caagcatcta cggtgtagtg
    44281 ggtgtgggtt atggtaaatt ccagaccact gaatacccga cctacaaaca cgacaccagc
    44341 gactacggtt tctcctacgg tgctggtctg cagttcaacc cgatggaaaa cgttgctctg
    44401 gacttctctt acgagcagag ccgtattcgt agcgttgacg taggcacctg gattgccggt
    44461 gttggttacc gcttctaatc actttggtga tataaaaaat ccgcctctcg gggcggattt
    44521 ttgtttttaa ggcttcgggt cgaaaatatc ggttccgaga tggttgtaat ccaccttctg
    44581 taactggaag ttggtgatgt atatcgaccc ggctttcttc tcagatataa acgggtattt
    44641 gatgttaatt tccttcgctt taattcccgt ccactgggag aaaaaaccta agaagtcatt
    44701 ggctgagcgg cgggctttaa tcacccgatg cgctttatcg tcgctggaaa tgaccataaa
    44761 aggcacctgg aaattttgct gatacttatc atcatgggca aggtattgca cgtctttgcc
    44821 gcgctcttta aaggccagac cgtggtcaga aaagtaaacc agcgagaagc tgctgccgct
    44881 gttgcgtaac tgatcgtaca gcttgcgcag taaatcgtcc gtttgcgtca tggtatagag
    44941 atagcacgac gtttctttcg actgcacaaa ggtttcgtat ttgccttgtg tcctgtcgca
    45001 ggcctgcgga tgtgagccca tcagatgtag aacaatcagc tgcggttgcg agtgctcttg
    45061 cgccagcact tgagcggtca tatccagtaa cgcttcgtct ttggtatttt tatctgcttc
    45121 aaaattacct tctttcagga agtacacttc atctgctcgt ttggcgatgc tggcgatagc
    45181 ggtatcgtat tcgccgattt gaccctggtt ggaaaaccac caggtctgga agcccgcgcg
    45241 atttgccagg gtgacaaagt tatcctgaaa ctgtggtttg ccatcgacta cgcgattgag
    45301 cgttaagcca agcgatttct gcgtggagcc actggcggca atgtagtcag caaatatcaa
    45361 accgttaacg ctgctggcaa acggggtatt gtcccagtga ccgccaaagg caccgagggc
    45421 atcgcgacgc gcgctttcac cgatcaccac cacataggtc tgatacttcg gcttaacggc
    45481 agtgaccgtc caggtatctt tcattccgga aagttttgcc atccgttctt gctcttcaat
    45541 cacctcgtta ttattgacga tgacatcctt agcaaaacga aataccggat agccagtatc
    45601 tttcagttta aatacgccgc cccaggccag gttttgcacg ggagcaacaa aaaatgtcgc
    45661 cacactgaat accagacaca ggctgtcgaa ggtattccag cgcgcttttt cactctcttt
    45721 ttttcgcctg attgctatta cgccgagcac aaaaataaat atgccgacca tgtagctgta
    45781 ccacggaaaa atcgtcagga tttcggtcga ctcttccata ttggtggagt gcaatgccag
    45841 caatgtattg aaattaggcg cgccgtaggc ctgagcaaaa gggaaataac aagccgccac
    45901 cagcgaactg acaccgacca gaactttttg tacgcgaggc aatgttcgcc atagcaaaag
    45961 caaaatagcc gtaaacgcag cggtgtagag caaactgaag gggtaaccta agccgaggtt
    46021 aattaatagc gactgtaaaa agtagaacgc agtccacggg ctaaataccc ggctacgggt
    46081 aacaagcgat tctttgaggg ttaaattcat atgccactat cgtaacaaac gccatgtgct
    46141 taccctggcg tcaagggtca atacctgcaa gagtgcgtga agagtggaaa ggggtccgca
    46201 tccgcgagcc gcaatatacg cagggctgca agaagataga gcgagccgcc gttcaggtca
    46261 actactgacg aacaaatctt ttgcgaaggg gattgcaaat ccgacaaaaa gtggggtttt
    46321 tcagaccaaa acgcgttatg cctgcatgaa agcaggagtg aagcggcgta ccgcgacgcc
    46381 gctatttatc ggaaggttta tcttgctgcg gtttgttgtt gaccatatcg cacaacatag
    46441 agagcagcat taaccgtact ttaaagggag aatgactaaa cacgcgcata cacctcttga
    46501 actcattcat aagacctcct gacttgctaa tcccgtcgat ccttgaggga tgattgcatt
    46561 acatacagat atagcacagg ctatattata tagctattgc taaaacgtta attttttgta
    46621 ccttcgcaac tctggtttac aatgtgcgca cgaaatgaga acgctatgta tgcgtcacca
    46681 taatgaggaa gcacaatgag tcgtcgcgca ggtacgccaa cagcaaaaaa agtgacgcag
    46741 ttagtgaacg tggaagagca cgttgaaggg ttccgccagg tcagagaggc gcatcggcgc
    46801 gagcttattg atgattacgt tgagctgatt tctgacttga tcagggaagt gggggaagct
    46861 cgtcaggtgg acatggctgc tcgtctggga gtttcgcaac cgacggtggc taaaatgctt
    46921 aagcggctgg caaccatggg gctgattgaa atgatcccct ggcgtggcgt gtttttaacg
    46981 gcagaaggag agaagctggc gcaggaaagc cgcgagcgac atcagatagt cgaaaatttc
    47041 ttgttggtgt tgggcgtcag tccggaaatc gcccgtcgcg acgcggaagg catggagcac
    47101 catgttagtg aagagacgct cgacgctttt cgtttgttta cccagaaaca cggtgccaaa
    47161 tgagcctgcc ttttttacgc acgctgcaag gcgatcgttt ttttcagtta ttaattcttg
    47221 ttggtatcgg attaagcttt ttcgtgccct ttgcaccgaa atcctggcct gctgctatcg
    47281 actggcacac catcatcacc ttaagcggcc tgatgctgct gaccaaaggt gtggagttaa
    47341 gcggttattt tgatgtgctg gggcgcaaaa tggtgcgccg ctttgctacg gagcgtcggc
    47401 tggcgatgtt tatggtgctg gcggcggcgc tgctttctac ctttctgacc aacgatgtcg
    47461 cgctgtttat tgttgttccg ctgactatca cgctaaaaag actgtgtgag atcccggtta
    47521 atcggctgat tatttttgag gcgctggcag tcaacgctgg ttcgctactg acgccaattg
    47581 gcaacccgca aaatattctt atctggggac gttctggtct ttcgtttgcc ggatttattg
    47641 cccaaatggc accgctggct ggcgcaatga tgctgacgct cctgctcctg tgctggtgtt
    47701 gtttccctgg aaaggcgctg caataccata cgggggtgca aacaccggag tggaaaccgc
    47761 ggctggtgtg gagttgtctg gggctgtata tcgtctttct gacggcgctg gagttcaaac
    47821 aagagctgtg gggactggtg attgtggcgg caggctttgc gctgctggca cgtcgcgtgg
    47881 tgctcagtgt ggactggacg ctgctgctgg tgtttatggc gatgtttatc gacgtccatt
    47941 tactgaccca gcttccagcg ttgcaaggcg tgttgggtaa cgtgagtcat ctatctgaac
    48001 ccgggttatg gttaacggca atcggtttat cgcaggtgat cagtaacgtg ccgagtacca
    48061 tattgttgct gaactatgtg ccgccgtctt tattactggt atgggcggta aacgtaggtg
    48121 gctttgggtt attacccgga tcgctggcaa atttgattgc gctacgtatg gcgaacgatc
    48181 gccgcatctg gtggcgtttc catctctatt caataccgat gctgttgtgt gcggcgttgg
    48241 tgggatatgt tttgttagtt atactcccgg ccaactaggg tctggcaaat aaaaaaggcg
    48301 gattatgagt ccgccttttg ctttaagttt tgaagattaa ttcagacgaa ccggcatccc
    48361 ggagcggttt ttaatcgctt catcaagaac aacctggtca acatctggct gaccggtcac
    48421 tgtttgcacg ctcttcgtca gggtaattgg cacaatttcc tgaccttcaa actgggcttc
    48481 ggtggtagac agcgggttat ggacttcaat ataacggctg ccgtctggct cggtggtcgc
    48541 ttttaccggc tcatcaataa actgtacgcg ggtaccgacc ggtactttct cgaacaggaa
    48601 tttgatgtct tcgttacgca gacgcacaca accatgactt acacgcaggc cgataccgaa
    48661 gttggcgttg gtgccatgga tagcgtacag gcgaccgatg tagagtgcat acagccccat
    48721 cgggttatcc ggacctgccg gaacgacagc cggaagcggt tcgcccgcag cgcggtactc
    48781 tgcgtgcatt ttggcggtcg gcgtccaggt cgggcctgct ttcttacgct caactttagt
    48841 ggtccagttg ataggcgtat ctttgcctaa ctgaccaatg ccgatcggca gcacgataac
    48901 ggtgttggtc cctttcggat agtaatacag acgcatctct gcactgttaa tgacgatgcc
    48961 ttcatgaacg gtatccggca ggatcagctg ctgcggaatg ttcagtacag taccgccttt
    49021 cggcaggaag gtatccacac ccgggttcgc ttccatcata ttggaaagcc ccatctggta
    49081 ctccgcggca aaatactcca gcggctgagt gttaccttca ggaatggtga tcacctgatt
    49141 ctgaccaacc aggcgactcc cgtcggttgg cagaggataa gttaccgcag aggcggtact
    49201 gcaaaagccg acaacagcga aggccgctgc gaataatgtt ttcaatttca tattcatgtt
    49261 aagcgagatt ttgtgcctgg caggccattg ggttgagaat attagagtat tggaagcgca
    49321 ttataagttc attccagctc acagtgaaat cagatgtgta cgaaatcaca ttttttgcct
    49381 ttggcttgag tgtagacctt aagcgaggag caggatcttc tttcagactt atggcataat
    49441 gcgcggtttg tcatatctct tttcaggata cgcctgtgtt agtttccagt aacgtcacca
    49501 tgcagttcgg cagtaagccg ttgtttgaaa acatttccgt caaatttggc ggcggcaacc
    49561 gttacggcct gattggcgcg aacggtagtg gtaaatccac ctttatgaag atcctcggcg
    49621 gcgacttaga gccgactttg ggtaacgttt ccctcgatcc caacgagcgc attggtaagc
    49681 tgcgtcagga tcagtttgcc tttgaagagt tcactgtgct ggatacggtg atcatggggc
    49741 ataaagagtt gtgggaagtg aagcaggagc gtgaccgcat ctatgctttg ccggaaatga
    49801 gtgaggaaga cggctataaa gtggccgatc tggaagttaa atacggcgaa atggacggtt
    49861 actctgcgga agctcgcgcc ggtgaattgt tgcttggcgt gggaattcca gtggaacagc
    49921 actacggccc gatgagtgaa gttgctcctg gctggaagct gcgtgtgctt ctggcgcagg
    49981 cgctgtttgc tgatccggat attctcctgc tcgacgaacc gaccaataac ctcgacatcg
    50041 acaccattcg ctggctggaa caggtgctga acgagcgtga cagcaccatg atcatcatct
    50101 cgcacgaccg tcacttcctt aacatggttt gtacccacat ggcggatctg gattacggcg
    50161 agctgcgcgt ttatccgggc aactacgatg agtacatgac ggcggcgacc caggcgcgtg
    50221 aacgtctgct ggctgataac gccaagaaga aagcgcagat tgctgagctg caatctttcg
    50281 ttagccgctt tagcgccaac gcctcgaaat ctcgccaggc aacttcgcgc gcgcgccaga
    50341 ttgataaaat caaactggaa gaggtgaaag cctccagccg tcagaacccg ttcatccgtt
    50401 ttgaacagga taagaaactg ttccgtaacg cgctggaagt ggaaggtctg accaaagggt
    50461 ttgataacgg tccactgttt aaaaatctca acttgctgct ggaggtcggt gaaaaacttg
    50521 cggtactggg taccaacggc gtcggtaaat caacgctgct gaaaacgctg gtgggcgatc
    50581 tgcaaccgga cagcggcacc gtaaaatggt ctgaaaacgc gcgcattggg tactatgctc
    50641 aggaccacga atatgagttt gaaaatgatc tgaccgtgtt cgaatggatg agccagtgga
    50701 agcaggaagg cgatgacgag caggcggtac gcagcattct cggtcgtttg ctgttcagcc
    50761 aggacgacat caaaaagcca gctaaagtgc tttccggtgg ggaaaaaggg cggatgctgt
    50821 ttggtaagtt aatgatgcag aagccgaaca ttctgatcat ggacgaaccg accaaccacc
    50881 tggatatgga atccatcgag tcactgaaca tggcgctgga actgtatcag ggcacgctga
    50941 tctttgtttc acacgaccgt gagttcgtaa gctccctggc gacccgcatt ctggaaatca
    51001 ccccggaacg cgtgatcgac tttagcggta attacgaaga ttacctgcgt agtaaaggga
    51061 tcgagtaagt gattatccgt caccccgata ctgtcggggt gacggcggct gatgacaaat
    51121 gcaaaat
//
LOCUS       DAZUDJ010000031        50294 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.031, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000031 DAZUDJ010000000
VERSION     DAZUDJ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 50294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50294
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.031"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..315)
                     /locus_tag="ACHY1N_002441"
     CDS             complement(<1..315)
                     /locus_tag="ACHY1N_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6531 domain-containing protein"
                     /protein_id="HFS4044741.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDIALPAPLPFILSRTYSSYRTKTPAPVGSLGPGWKMPADI
                     RLQ"
     gene            544..1152
                     /gene="yibF"
                     /locus_tag="ACHY1N_002442"
     CDS             544..1152
                     /gene="yibF"
                     /locus_tag="ACHY1N_002442"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HFS4044742.1"
                     /translation="MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFN
                     PLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMD
                     AGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA"
     gene            1250..2641
                     /gene="selA"
                     /locus_tag="ACHY1N_002443"
     CDS             1250..2641
                     /gene="selA"
                     /locus_tag="ACHY1N_002443"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004125 - L-seryl-tRNA(Sec) selenium
                     transferase activity [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HFS4044743.1"
                     /translation="MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQML
                     DEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAE
                     AAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNEN
                     TALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEP
                     MPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLS
                     QIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRC
                     LEDEQRFLEMLLK"
     gene            2638..4482
                     /gene="selB"
                     /locus_tag="ACHY1N_002444"
     CDS             2638..4482
                     /gene="selB"
                     /locus_tag="ACHY1N_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HFS4044744.1"
                     /translation="MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLT
                     GNPMLTVALTKADRVDEARVNEVERQVKEVLREYGFAEAKLFITAATEGRGIDALREH
                     LLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRV
                     RALHAQNQPTETANAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHT
                     PLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRLVLRDISARNTLAG
                     ARVVMLNPPRRGKRKPEYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGE
                     GMRELLQQPGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMAL
                     PMEDEALVLLLIEKMRESGDILSHHGWLHLPDHKAGFSEEQQAIWQKAEPLFGDEPWW
                     VRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDLDQECGS
                     TCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDHLLRDALLFPEK"
     gene            4670..5821
                     /gene="yiaY"
                     /locus_tag="ACHY1N_002445"
     CDS             4670..5821
                     /gene="yiaY"
                     /locus_tag="ACHY1N_002445"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine dehydrogenase"
                     /protein_id="HFS4044745.1"
                     /translation="MASSTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDSMLTK
                     LGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHD
                     CAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
                     MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALK
                     AVTMIAENLPLAVEDGSNAKAREAMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLP
                     HGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGAEACINAIRELAKKV
                     DIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM"
     gene            5986..7524
                     /gene="aldB"
                     /locus_tag="ACHY1N_002446"
     CDS             5986..7524
                     /gene="aldB"
                     /locus_tag="ACHY1N_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase AldB"
                     /protein_id="HFS4044746.1"
                     /translation="MTNNPPSAQIKPGEYGFPLKLKARYDNFIGGEWVAPADGEYYQN
                     LTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGV
                     VNVVNGAGGEIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSVTQMGAQVSHGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLE
                     PTILFGQNNMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(7743..7898)
                     /locus_tag="ACHY1N_002447"
     CDS             complement(7743..7898)
                     /locus_tag="ACHY1N_002447"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044747.1"
                     /translation="MAKLMNNSSKTSTVQIKRIKPSIIYRLLLIGLGSPMVIYGLIRP
                     LTIETRD"
     gene            8069..8392
                     /gene="yiaW"
                     /locus_tag="ACHY1N_002448"
     CDS             8069..8392
                     /gene="yiaW"
                     /locus_tag="ACHY1N_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HFS4044748.1"
                     /translation="MFLDYFALGVLIFVFLVIFYGIIILHDIPYLIAKKRNHPHADAI
                     HVAGWVSLFTLHVIWPFLWIWATLYRPERGWGMQNHDSSVVQLQQRIAGLEKQLADIK
                     SSSAE"
     gene            8398..9534
                     /gene="yiaV"
                     /locus_tag="ACHY1N_002449"
     CDS             8398..9534
                     /gene="yiaV"
                     /locus_tag="ACHY1N_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFS4044749.1"
                     /translation="MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLI
                     LLMNYNHPYTFKAQKAVISIPVVPQVTGVVIEVTDKKNTLIKKGEVLFRLDPTRYQAR
                     VDRLMADIVTAEHKQRALGAELDEMAANTQQAKATRDKFAKEYQRYARGSQAKVNPFS
                     ERDIDVARQNYLAQEASVKSSAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLE
                     QTIVRAPSDGYVTQVLIRPGTYAASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGD
                     DAEVVFNALPGKVFSGKLAAISPAVPGGAYQSTGTLQTLNTAPGSDGVIATIELDEHT
                     DLSALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWVHYLYLDH"
     gene            complement(9531..10505)
                     /gene="yiaU"
                     /locus_tag="ACHY1N_002450"
     CDS             complement(9531..10505)
                     /gene="yiaU"
                     /locus_tag="ACHY1N_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4044750.1"
                     /translation="MTKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADF
                     ESKVGLKVFDRTTRQLMLTPFGTALLPYINDMLDRNEQLNNFIADYKHEKRGRVTIYA
                     PTGIITYLSKHVIDKIKDIGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDE
                     SLVASFITQYAVTAYASQRYLEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGS
                     KEVRDYRVKGNYVCDNTQSALELARNHLGIVFAPDKSVQSDLQDGTLVPCFQHPYEWW
                     LDLVAIFRKREYQPWRVQYVLDEMLREIRHQLAQSQQLRPEQAAESED"
     gene            10629..11369
                     /gene="yiaT"
                     /locus_tag="ACHY1N_002451"
     CDS             10629..11369
                     /gene="yiaT"
                     /locus_tag="ACHY1N_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0030674 - protein-macromolecule adaptor
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MipA/OmpV family protein"
                     /protein_id="HFS4044751.1"
                     /translation="MLINRNIVALFALPFMASATASELSIGAGAAYNESPYRGYNENT
                     KAIPLISYEGDSFYVRQTTLGFILSQSEKNELSLTASWMPLEFDPADNDDHAMQQVDK
                     RDSTAMAGVAWYHHERWGTVKASAAADVLDNSNGWVGELSVFHKMQIGRLSLTPALGV
                     LYYDENFSDYYYGISESESRRSGLASYSAQDAWVPYVSLTAKYPIGEHVVLMASAGYS
                     ELPEEITDSPMIDRNESFTFVTGVSWRF"
     gene            complement(11316..11579)
                     /locus_tag="ACHY1N_002452"
                     /pseudo
     CDS             complement(11316..11579)
                     /locus_tag="ACHY1N_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11583..11684
                     /locus_tag="ACHY1N_002453"
                     /pseudo
     CDS             11583..11684
                     /locus_tag="ACHY1N_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            complement(11716..12411)
                     /gene="araD"
                     /locus_tag="ACHY1N_002454"
     CDS             complement(11716..12411)
                     /gene="araD"
                     /locus_tag="ACHY1N_002454"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0019568 - arabinose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFS4044752.1"
                     /translation="MLEQLKADVLAANLALPAHHLVTFTWGNVSAVDETRQWMVIKPS
                     GVEYDVMTADDMVVVEIASGKVVEGSKKPSSDTPTHLALYRRYAEIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRQMTAEEINGEYEYQTGEVIIETFEERGRSP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPAMQNELLDKH
                     YLRKHGANAYYGQ"
     gene            complement(12405..13265)
                     /gene="sgbU"
                     /locus_tag="ACHY1N_002455"
     CDS             complement(12405..13265)
                     /gene="sgbU"
                     /locus_tag="ACHY1N_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418039.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFS4044753.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLDWSTAQRTSLVAAMIETGVGIPSMCLSAHRRFPFGSRDDAVRQRAREIMSKAIR
                     LARDLGIRTIQLAGYDVYYEDHDEGTRQRFAEGLAWAVEQAAASQVMLAVEMMDTAFM
                     NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTE
                     QSPGQFRDVPFGEGCVDFVGIFKTLHKLNYRGSFLIEMWTEKAKEPVLEIIQARRWIE
                     ARMQEAGFIC"
     gene            complement(13258..13920)
                     /gene="ulaD"
                     /locus_tag="ACHY1N_002456"
     CDS             complement(13258..13920)
                     /gene="ulaD"
                     /locus_tag="ACHY1N_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFS4044754.1"
                     /translation="MSRPLLQLALDHSSLEAAQRDVTQLKDSVDIVEAGTILCLNEGL
                     GAVKALREQCPDKIIVADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMA
                     QRCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFKDIRVKAFIAGRALAGSANPAQVAGDFHAQIDAIWGGK
                     RA"
     gene            complement(13917..15413)
                     /gene="lyxK"
                     /locus_tag="ACHY1N_002457"
     CDS             complement(13917..15413)
                     /gene="lyxK"
                     /locus_tag="ACHY1N_002457"
                     /EC_number="2.7.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulokinase"
                     /protein_id="HFS4044755.1"
                     /translation="MTQYWLGLDCGGSWLKAGLYDREGREAGVQRLPLCALSPQPGWA
                     ERDMAELWQCCMAVIRELLTHSGVSGEQIVGIGISAQGKGLFLLDKNNKPLGNAILSS
                     DRRAMEIVRRWQEDGIPEKLYPLTRQTLWTGHPVSLLRWLKEHEPERYAQIGCVMMTH
                     DYLRWCLTGVKGCEESNISESNLYNMSLGEYDPCLTDWLGIAEINHALPPVVGSAEIC
                     GEITAQTAVLTGLKAGTPVVGGLFDVVSTALCAGIEDEFTLNAVMGTWAVTSGITRGL
                     RDGEAHPYVYGRYVNDGEFIVHEASPTSSGNLEWFTAQWGEISFDEINQAVASLPKAG
                     GDLFFLPFLYGSNAGLEMTSGFYGMQAIHTRAHLLQAIYEGGVFSHMTHLNRMRERFT
                     DVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGAALAARVGTGVYRDFSE
                     AQRDLQHPVRTLLPDMTAHQLYQQKYQRYQHLIAALQGFHARIKEHIL"
     gene            complement(15417..16403)
                     /gene="yiaO"
                     /locus_tag="ACHY1N_002458"
     CDS             complement(15417..16403)
                     /gene="yiaO"
                     /locus_tag="ACHY1N_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter
                     substrate-binding protein YiaO"
                     /protein_id="HFS4044756.1"
                     /translation="MKLRSVTYALFIAGLAAFSTSSLAAQSLRFGYETSQTDSQHIAA
                     KKFNDLLQERTKGELKLKLFPDSTLGNAQAMISGVRGGTIDMEMSGSNNFAGLSPVMN
                     LLDVPFLFRDTAHAHKTLDGKVGDDLKASLEGKGLKVLAYWENGWRDVTNSRAPVKTP
                     ADLKGLKIRTNNSPMNIAAFKVFGANPIPMPFAEVYTGLETRTIDAQEHPINVVWSAK
                     FFEVQKYLSLTHHAYSPLLVVINKAKFDGLSPEFQQALISSAQEAGNYQRKLVAEDQQ
                     KIIDGMKEAGVEVITDLDRKAFSDALGNQVRDMFVKDVPQGADLLKAVDEVQ"
     gene            complement(16416..17693)
                     /gene="yiaN"
                     /locus_tag="ACHY1N_002459"
     CDS             complement(16416..17693)
                     /gene="yiaN"
                     /locus_tag="ACHY1N_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter large
                     permease YiaN"
                     /protein_id="HFS4044757.1"
                     /translation="MAVLIFLGCLLGGIAIGLPIAWALLLCGAALMFWLDMFDVQIMA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAM
                     IMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFG
                     VSSGLSISKLFMAGIAPGMMMGATLMLTWWWQASRLNLPRQQKATMQEIWHSFVSGIW
                     ALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTS
                     VVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMVAILIVGMVMDLTP
                     TVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDA
                     VRGVFPYVLVLYSLLVVFVFIPDLIILPLKWIN"
     gene            complement(17696..18169)
                     /gene="yiaM"
                     /locus_tag="ACHY1N_002460"
     CDS             complement(17696..18169)
                     /gene="yiaM"
                     /locus_tag="ACHY1N_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HFS4044758.1"
                     /translation="MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYL
                     FVWLTFIGAIVAFMDNAHVQVTFLVEKLSPAWQRRVALVTHSLILFICGALAWGATLK
                     TIQDWSDYSPILGLPIGLMYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA"
     gene            complement(18287..18754)
                     /gene="yiaL"
                     /locus_tag="ACHY1N_002461"
     CDS             complement(18287..18754)
                     /gene="yiaL"
                     /locus_tag="ACHY1N_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HFS4044759.1"
                     /translation="MIFGHIAQPNPCRLPAAIEKALDFLRATDFNALEPGVVEIDGKN
                     IYAQIIDLTTREAVENRPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRDI
                     IFYHDSEHESFIEMIPGSYAIFFPQDVHRPGCILQTASEIRKIVVKVALTALN"
     gene            complement(18766..19764)
                     /gene="yiaK"
                     /locus_tag="ACHY1N_002462"
     CDS             complement(18766..19764)
                     /gene="yiaK"
                     /locus_tag="ACHY1N_002462"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047559 - 3-dehydro-L-gulonate
                     2-dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HFS4044760.1"
                     /translation="MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAA
                     DHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRI
                     LPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPT
                     RDAKLQRIMDYVTTAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL"
     gene            19965..20813
                     /gene="yiaJ"
                     /locus_tag="ACHY1N_002463"
     CDS             19965..20813
                     /gene="yiaJ"
                     /locus_tag="ACHY1N_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HFS4044761.1"
                     /translation="MGKEVMGKKENEMAQEKERPAGSQSLFRGLMLIEILSNYPNGCP
                     LAHLSELAGLNKSTVHRLLQGLQSCGYVTTAPAAGSYRLTTKFIAVGQKALSSLNIIH
                     IAAPHLEALNIATGETINFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMG
                     KIYMAFGHPDYVKSYWENHQHEIQPLTRNTITELPAMFDELAHIRESGAAMDREENEL
                     GVSCIAVPVFNIHGRVPYAVSISLSTSRLKQVGEKNLLKPLRETAQAISNELGFTVRD
                     DQGAIT"
     gene            20915..21388
                     /gene="ysaA"
                     /locus_tag="ACHY1N_002464"
     CDS             20915..21388
                     /gene="ysaA"
                     /locus_tag="ACHY1N_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFS4044762.1"
                     /translation="MNRFIIADATKCIGCRTCEVACAVSHQENQDCAALSPDEFISRI
                     RVIKDHSWTTAVACHQCEDAPCANVCPVNAISREHGHIFVEQTRCIGCKSCMLACPFG
                     AMEVVSSRKKARAIKCDLCWHRETGPACVEACPTKALQCMDVEKVQRHRLRQQPV"
     gene            complement(21540..22793)
                     /gene="avtA"
                     /locus_tag="ACHY1N_002465"
     CDS             complement(21540..22793)
                     /gene="avtA"
                     /locus_tag="ACHY1N_002465"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HFS4044763.1"
                     /translation="MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIP
                     EMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEAQNIAL
                     TNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGI
                     ISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHK
                     PEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYV
                     PEPEKIEAGVKILAEEIERAWAESH"
     gene            complement(22971..25001)
                     /gene="malS"
                     /locus_tag="ACHY1N_002466"
     CDS             complement(22971..25001)
                     /gene="malS"
                     /locus_tag="ACHY1N_002466"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HFS4044764.1"
                     /translation="MKLAACFLTLLPGFAVAASWTSPGFPAFSEQGTGTFVSHAQLPK
                     GTRPLTLNFDQQCWQPADAIKLNQMLSLQPCSNTPPQWRLFRDGKYTLQIDTRSGTPT
                     LMISIQNAAEPVANLVRECPKWDGLPLTLDVSATFPEGAAVRDYYSQQIAIVKNGQIT
                     LQPAATSNGLLLLERAETDAPAPFDWHNATVYFVLTDRFENGDPSNDQSYGRHKDGMA
                     EIGTFHGGDLRGLTNKLDYLQQLGVNALWISAPFEQIHGWVGGGTKGDFPHYAYHGYY
                     TQDWTNLDANMGNEADLRTLVDSAHQRGIRILFDVVMNHTGYATLADMQEYQFGALYL
                     SGDEVKKTLGERWSDWKPAAGQTWHSFNDYINFSDKTGWDKWWGKNWIRTDIGDYDNP
                     GFDDLTMSLAFLPDIKTESTTASGLPVFYKNKTDTHAKVIEGFTPRDYLTHWLSQWVR
                     DYGIDGFRVDTAKHVELPAWQQLKTEASAALREWKKANPDKALDDKPFWMTGEAWGHG
                     VMQSDYYRHGFDAMINFDYQEQAAKAVDCLAQMDTTWQQMAEKLQGFNVLSYLSSHDT
                     RLFREGGDKAAELLLLAPGAVQIFYGDESSRPFGPTGSDPLQGTRSDMNWQDVSGKSA
                     ANVAHWQKISQFRARHPAIGAGKQTTLSLKQGYGFVREHGDDKVLVIWAGQQ"
     gene            25321..26145
                     /gene="bax"
                     /locus_tag="ACHY1N_002467"
     CDS             25321..26145
                     /gene="bax"
                     /locus_tag="ACHY1N_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HFS4044765.1"
                     /translation="MILTPIRRYGAMILMLLTLVFSSEVLAKTHTTTASQKSHLTKAS
                     NKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITAERNWL
                     ISKQYQGQWSPAERARLKDIAKRYKVKWSGNTRKIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARNNNNLFGMKCMKGRCTNAPGKVKGYSQFSSVKESVSAYVTNLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTKGKSYNNYLFAMYQDNQRLIAAHM"
     gene            complement(26253..27431)
                     /gene="xylR"
                     /locus_tag="ACHY1N_002468"
     CDS             complement(26253..27431)
                     /gene="xylR"
                     /locus_tag="ACHY1N_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312479.1"
                     /note="D-xylose enhances binding of XylR to the xyl
                     promoter and activates transcription; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose utilization transcriptional activator
                     XylR"
                     /protein_id="HFS4044766.1"
                     /translation="MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATD
                     NYALVESAFLHLKEKGVNRFSFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRS
                     TDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMI
                     HAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEIML
                     "
     gene            complement(27509..28690)
                     /gene="xylH"
                     /locus_tag="ACHY1N_002469"
     CDS             complement(27509..28690)
                     /gene="xylH"
                     /locus_tag="ACHY1N_002469"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose ABC transporter permease XylH"
                     /protein_id="HFS4044767.1"
                     /translation="MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFT
                     WTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGVAAICD
                     VWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
                     TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVV
                     GRQALTAIIVLGAIWLLNDYRGVPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLE
                     AARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNIAELDAIAACVIGG
                     TSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRR
                     S"
     gene            complement(28668..30209)
                     /gene="xylG"
                     /locus_tag="ACHY1N_002470"
     CDS             complement(28668..30209)
                     /gene="xylG"
                     /locus_tag="ACHY1N_002470"
                     /EC_number="7.5.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015614 - ABC-type D-xylose transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015753 - D-xylose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter ATP-binding protein"
                     /protein_id="HFS4044768.1"
                     /translation="MPYLLEMKNITKTFGSVKAIDNVCLRLNAGEIVSLCGENGSGKS
                     TLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENI
                     FLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQ
                     VRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDG
                     QHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKR
                     VNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQA
                     IAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQL
                     KVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQ
                     LVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHV
                     EKQSV"
     gene            complement(30287..31279)
                     /gene="xylF"
                     /locus_tag="ACHY1N_002471"
     CDS             complement(30287..31279)
                     /gene="xylF"
                     /locus_tag="ACHY1N_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015753 - D-xylose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4044769.1"
                     /translation="MKIKNILLTLCTSLLLTNVAAHAKEVKIGMAIDDLRLERWQKDR
                     DIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA
                     KQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNN
                     AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVAS
                     NDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAE
                     IAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVVKDGFHKESEL"
     gene            31645..32967
                     /gene="xylA"
                     /locus_tag="ACHY1N_002472"
     CDS             31645..32967
                     /gene="xylA"
                     /locus_tag="ACHY1N_002472"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009045 - xylose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HFS4044770.1"
                     /translation="MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHD
                     VDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVE
                     HKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAG
                     HSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNS
                     ELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK"
     gene            33039..34493
                     /gene="xylB"
                     /locus_tag="ACHY1N_002473"
     CDS             33039..34493
                     /gene="xylB"
                     /locus_tag="ACHY1N_002473"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFS4044771.1"
                     /translation="MYIGIDLGTSGVKVILLNEQGEVVASQTEKLTVSRPHPLWSEQD
                     PEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCA
                     QECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
                     TGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAK
                     AWGMATVPVVAGGGDNAAGAVGVGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHS
                     FCHALPQRWHLMSVMLSAASCLDWVAKLTGLCNVPALIAAAQQADESAEPVWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTL
                     IGGGARSEYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLP
                     LEQSHLPDAQRYAAYQPRRETFRRLYQQLLPLMA"
     gene            34662..35003
                     /gene="yiaB"
                     /locus_tag="ACHY1N_002474"
     CDS             34662..35003
                     /gene="yiaB"
                     /locus_tag="ACHY1N_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YiaB"
                     /protein_id="HFS4044772.1"
                     /translation="MKTSKTVAKLLFVVGALVYLVGLWISCPLLSGKGYFLGVLMTAT
                     FGNYAYLRAEKLGQLDNFFTHICQLVALITIGLLFIGVLNAPINAYEMVIYPIAFFVC
                     LFGQMRLFRSV"
     gene            35049..35486
                     /gene="yiaA"
                     /locus_tag="ACHY1N_002475"
     CDS             35049..35486
                     /gene="yiaA"
                     /locus_tag="ACHY1N_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YiaA"
                     /protein_id="HFS4044773.1"
                     /translation="MDNKISTYSPAFSIVSWIALVGGIVTYLLGLWNAEMQLNEKGYY
                     FAVLVLGLFSAASYQKTVRDKYEGIPTTSIYYMTCLTVFIISVALLMVGLWNATLLLS
                     EKGFYGLAFFLSLFGAVAVQKNIRDTGINPPKETQVTQEEYSE"
     gene            complement(35528..36523)
                     /gene="wecH"
                     /locus_tag="ACHY1N_002476"
     CDS             complement(35528..36523)
                     /gene="wecH"
                     /locus_tag="ACHY1N_002476"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase WecH"
                     /protein_id="HFS4044774.1"
                     /translation="MQPKIYWIDNLRGIACLMVVMIHTTTWYVTNAHSVSPVTWDIAN
                     VLNSASRVSVPLFFMISGYLFFGERSAQPRHFLRIGLCLIFYSAIALLYIALFTSINM
                     ELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMVVIGIIANPNTV
                     PQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVSAALFATGVFII
                     SRGTLYELQWRGNFADTWYLYCGPMVFICAIALLTLVKNTLDTRTIRGLGLISRHSLG
                     IYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAASLLLSMLVQRIDRNRLVS"
     gene            36698..36997
                     /gene="ysaB"
                     /locus_tag="ACHY1N_002477"
     CDS             36698..36997
                     /gene="ysaB"
                     /locus_tag="ACHY1N_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YsaB family lipoprotein"
                     /protein_id="HFS4044775.1"
                     /translation="MMMNAFFPAMALMVLVGCSTPSPVQKAQRVKVDPLRSLNMEALC
                     KDQAAKRYNTGEQKIDVTAFEQFQGSYEMRGYTFRKEQFVCSFDADGHFLHLSMR"
     gene            37092..38003
                     /gene="glyQ"
                     /locus_tag="ACHY1N_002478"
     CDS             37092..38003
                     /gene="glyQ"
                     /locus_tag="ACHY1N_002478"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFS4044776.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            38013..40082
                     /gene="glyS"
                     /locus_tag="ACHY1N_002479"
     CDS             38013..40082
                     /gene="glyS"
                     /locus_tag="ACHY1N_002479"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFS4044777.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDK
                     LEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRLNRLTMLEKLRELFLRV
                     ADISLLQ"
     gene            40408..40560
                     /gene="hokA"
                     /locus_tag="ACHY1N_002480"
     CDS             40408..40560
                     /gene="hokA"
                     /locus_tag="ACHY1N_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012540334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokA"
                     /protein_id="HFS4044778.1"
                     /translation="MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFL
                     ACNLKE"
     gene            complement(40549..40608)
                     /locus_tag="ACHY1N_002481"
     CDS             complement(40549..40608)
                     /locus_tag="ACHY1N_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044779.1"
                     /translation="MRNAVRKAGITSRRRLLLF"
     gene            complement(40748..40960)
                     /gene="cspA"
                     /locus_tag="ACHY1N_002482"
     CDS             complement(40748..40960)
                     /gene="cspA"
                     /locus_tag="ACHY1N_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HFS4044780.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(41241..41531)
                     /gene="yiaG"
                     /locus_tag="ACHY1N_002483"
     CDS             complement(41241..41531)
                     /gene="yiaG"
                     /locus_tag="ACHY1N_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HFS4044781.1"
                     /translation="MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKG
                     TGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKLMRLIQANPALSKQLME"
     gene            41965..42675
                     /gene="yiaF"
                     /locus_tag="ACHY1N_002484"
     CDS             41965..42675
                     /gene="yiaF"
                     /locus_tag="ACHY1N_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HFS4044782.1"
                     /translation="MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNT
                     VMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQTDDLKPVFDQAFTKVVTTP
                     ADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLP
                     AQHQAFNQAWTTAVTATQ"
     gene            complement(42725..43699)
                     /gene="ghrB"
                     /locus_tag="ACHY1N_002485"
     CDS             complement(42725..43699)
                     /gene="ghrB"
                     /locus_tag="ACHY1N_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HFS4044783.1"
                     /translation="MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFA
                     EAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTET
                     VADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLF
                     GAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLS
                     MANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD"
     gene            complement(43803..44462)
                     /gene="yiaD"
                     /locus_tag="ACHY1N_002486"
     CDS             complement(43803..44462)
                     /gene="yiaD"
                     /locus_tag="ACHY1N_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HFS4044784.1"
                     /translation="MKKRVYLIAAVVSGALAVSGCTTNPYTGEREAGKSAIGAGLGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVIGYTDSTGGHDL
                     NMRLSQQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGKAQNRRVEITLSP
                     L"
     gene            44615..46948
                     /gene="bisC"
                     /locus_tag="ACHY1N_002487"
     CDS             44615..46948
                     /gene="bisC"
                     /locus_tag="ACHY1N_002487"
                     /EC_number="1.8.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418007.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin sulfoxide reductase"
                     /protein_id="HFS4044785.1"
                     /translation="MANSSSRYSVLTAAHWGPMLVETDGETVFSSHGALATGMENSLQ
                     SAVRDQVHSNTRVRFPMVRKGFLASPENPQGIRGQDEFVRVSWDEALDLIHQQHKRIR
                     EAYGPASIFAGSYGWRSNGVLHKASTLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
                     GGSEVYQQQTSWPLVLEHSDVVVLWSANPLNTLKIAWNASDEQGLSYFSALRDSGKKL
                     ICIDPMRSETVDFFGDKMEWVAPHMGTDVALMLGIAHTLVENGWHDEAFLTRCTTGYA
                     VFASYLLGESDGIAKNAEWAAEICGVNAAKIRELAALFHQNTTMLMAGWGMQRQQFGE
                     QKHWMIVTLAAMLGQIGTPGGGFGLSYHFANGGNPTRRSAVLSSMQGSLPGGCDAVDK
                     IPVARIVEALENPGGAYQHNGMNRHFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSFERNDLTMTGDYSNQHLVPMKQVVPPRYEARNDF
                     DVFAELSERWEKGGYARFTEGKSQLQWLETFYNVARQRGASQQVELPPFAEFWQANQL
                     IEMPENPDSERFIRFADFCRDPLAHPLKTASGKIEIFSQRIADYGYPDCPGHPMWLEP
                     DEWQGNAEPEQLQVLSAHPAHRLHSQLNYSSLRELYAVANREPVTIHPDDAQARGITE
                     GDMVRVWNSRGQILAGAVISEGIKPGVICIHEGAWPDLDLTADGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALAWLEKYNGPELTLTAFEPPASS"
     gene            complement(46917..47357)
                     /gene="yiaC"
                     /locus_tag="ACHY1N_002488"
     CDS             complement(46917..47357)
                     /gene="yiaC"
                     /locus_tag="ACHY1N_002488"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HFS4044786.1"
                     /translation="MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAY
                     LANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRYPHLML
                     EVYQKNQPAIDFYRAQGFHIVDCAWQDETQLPTWIMSWPVVQTL"
     gene            complement(47354..47917)
                     /gene="tag"
                     /locus_tag="ACHY1N_002489"
     CDS             complement(47354..47917)
                     /gene="tag"
                     /locus_tag="ACHY1N_002489"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFS4044787.1"
                     /translation="MERCGWVSQDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGL
                     SWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY
                     LQMEQNGEPFADFVWSFVNHQPQVTQATTLSEIPTSTSASDALSKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHVVGCCCYPGNKP"
     gene            48075..48773
                     /gene="yhjY"
                     /locus_tag="ACHY1N_002490"
     CDS             48075..48773
                     /gene="yhjY"
                     /locus_tag="ACHY1N_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HFS4044788.1"
                     /translation="MIIKKSGGRWQLSLLASVVISAFFLNTAYAWQQEYIVDTQPGHS
                     TERYTWDSDHQPDYNDILSQRIQSSQRALGLEVNLAEETPVDVTSSMSMGWNFPLYEQ
                     VTTGPVAALHYDGTTTSMYNEFGDSTTTLTDPLWHASVSSLGWRVDSRLGDLRPWAQI
                     SYNQQFGENIWKAQSGLSRMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQAENTTN
                     NSDYLYTMGVSARF"
     gene            49002..50204
                     /gene="yhjX"
                     /locus_tag="ACHY1N_002491"
     CDS             49002..50204
                     /gene="yhjX"
                     /locus_tag="ACHY1N_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4044789.1"
                     /translation="MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLDAP
                     VSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSNNLMML
                     WLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTQLLE
                     TVGLEKTFVIWGAIALVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWM
                     LAVMFLTACMSGLYVIGVAKDIAQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDK
                     IARIRVITIGQVISLVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFG
                     LNNLAKNYGVIYLGFGIGSICGSIIASLFGGFYVTFYVIFALLILSLALSTTIRQPEQ
                     KVLREAHI"
BASE COUNT        12227 a        12455 c        13096 g        12516 t
ORIGIN      
        1 ctgtaagcgg atatccgcag gcattttcca gccggggccg aggctcccca ccggcgcggg
       61 cgtttttgtc cggtaactgc tgtaggtgcg ggagaggatg aacggcagcg gggcgggcag
      121 ggcgatgtcg gtttcaccgg gaaggacctt tgcaccgagc agaggattga ccggatggcc
      181 ggacgtcact ccgccggggc acaccgaaca ggccacgccg gtgggggcac caatgcgcac
      241 cccggctgaa ccctgaacaa tgctaccgcc atactgcgtc atgtcgccct gacgcgctgc
      301 cggttttccg ctcatctgct catccttgtt ttatcgggtt atttgtctgc ttccaggcaa
      361 aaccctacag atttataaga aagccttaag tgagatatcc atcagataga aacaattagg
      421 aaaatattta tatcaccatg ataaatatgt gatttatttg gaagtaacaa accatcaaca
      481 ttttctgccc tttttcccat caccaggcca tactgatatt tttcctcgca caaaggactc
      541 ggcatgaaac tcgtcggtag ctacaccagc ccgtttgtac gcaaactttc tattctgttg
      601 ttagaaaagg gcataacttt cgaatttatt aatgaactgc cctataacgc ggacaacggc
      661 gtggcgcaat ttaacccgtt aggaaaagtg ccggtgctgg tgaccgaaga gggcgaatgt
      721 tggtttgatt cgccgatcat cgctgaatat attgaattaa tgaatgtcgc tccggcgatg
      781 ttgccgcgcg atccgctgga gtcgttgcgg gtgcgcaaaa ttgaggcact ggcggatggc
      841 attatggatg ccgggctggt atcggtgcgt gaacaggcgc gtccagcggc gcagcagtct
      901 gaagatgaat tgttacgcca gcgggagaaa atcaaccgca gtctggatgt gctggaagga
      961 tatctggtcg atggcacact caaaaccgat acggtcaatc tggcgactat cgccattgcc
     1021 tgtgccgtcg gatatctcaa tttccgccgc gttgcgccag gttggtgtgt cgaccgccca
     1081 cacttagtca aactggtcga aaacctgttt agccgcgaaa gttttgctcg caccgaaccg
     1141 ccaaaggctt gatgcgcgat atgtcctcct gacccatctc acgttacaat ccgtggttat
     1201 gttaaacgcc cttctccgtg tgagagggcc ttgatcagcc aggtttccta tgacaaccga
     1261 aacgcgttcc ctctatagtc aacttccggc tattgatcgc ttattgcgcg atagctcctt
     1321 cctttctttg cgtgatactt atggtcacac ccgcgtggtg gaattgttgc gtcagatgct
     1381 cgacgaagcg cgagaagtga ttcgtggcag ccagacgctg cctgcgtggt gtgaaaactg
     1441 ggcgcaagaa gtcgatgccc ggttgacgaa agaagcgcag agcgcgctgc gtccggtgat
     1501 caacctgacg ggaaccgtgc tgcataccaa ccttggacga gctttacagg cggaagccgc
     1561 ggtggaagcc gttgcgcagg ctatgcgttc gccagtgacc ctcgagtacg atctggacga
     1621 cgccggacgc ggacatcgcg atcgggcgct ggcgcaactg ctgtgccgca ttacgggggc
     1681 ggaagatgcc tgtatcgtta ataacaatgc ggcggcggtg ttattgatgt tggcggccac
     1741 tgccagcggg aaagaggtgg tggtttctcg cggcgaactg gtggagattg gcggcgcgtt
     1801 tcgtattccc gatgttatgc gtcaggcagg ctgcacccta cacgaagtag ggaccaccaa
     1861 ccgcacgcac gcgaatgatt atcgtcaggc ggtgaatgaa aataccgcac tgttgatgaa
     1921 agtacatacc agtaactaca gcattcaggg gttcaccaaa gcgatagatg aagcggaact
     1981 ggtggcgctc ggcaaagagc tggatgttcc cgtagtgact gatttaggca gtggctcgct
     2041 ggtcgatctt agccagtacg gtttgccgaa agagccaatg ccgcaggagt tgattgcggc
     2101 gggcgtcagt ctggtgagtt tctccggcga caagttgtta ggcgggccgc aggcaggaat
     2161 tattgttggt aaaaaagaga tgatcgcccg cctgcaaagc cacccgctga agcgtgcatt
     2221 acgcgcggat aaaatgaccc tcgcggcgct ggaagccacg ttgcgtcttt atttacaccc
     2281 tgaagctctg agtgaaaaat taccgaccct gcgcctgctt acccgcagcg cagaggtcat
     2341 tcaaatccag gcacaacgtt tacaggcccc ccttgccgca cattacggcg cggagtttgc
     2401 ggtacaggtt atgccatgtc tttcgcagat tggcagtggt tcgctgccgg ttgatcgcct
     2461 gccgagcgcg gcattaacgt ttacacccca tgatggacgc ggtagccacc ttgagtcatt
     2521 agccgcccgc tggcgtgaat tgccagtgcc ggtgattggt cgtatttatg acggacgatt
     2581 gtggctggat ttacgctgcc ttgaagatga gcaacggttt ttggagatgt tgttgaaatg
     2641 attattgcga ctgccggaca cgttgaccac ggcaaaacaa ccttattgca ggcgattact
     2701 ggcgtaaatg ctgaccgtct gccggaagaa aaaaagcgcg gcatgaccat cgatctcggc
     2761 tatgcctact ggccgcagcc ggatggtcgc gtgcctggtt ttatcgacgt acccggtcat
     2821 gaaaagtttc tttccaacat gctggcgggc gttggtggta tcgatcacgc gctgttggtg
     2881 gtggcgtgcg atgacggcgt gatggcacag acccgtgagc atctggcgat tttgcagctg
     2941 accggtaacc cgatgctgac agtggcgctg accaaagccg atcgcgtgga cgaagcgcgt
     3001 gttaatgagg ttgaacgcca ggtaaaggag gtgctgcggg aatacggttt tgctgaggca
     3061 aaactgttta tcaccgcagc aaccgaaggt cggggaattg atgccctgcg cgagcatctg
     3121 cttcagttgc cggaacgcga gcacgccagc caacatagtt tccgcctcgc tattgaccgc
     3181 gcatttaccg taaaaggtgc cgggctggtc gtcaccggta cggcgttaag cggggaagtg
     3241 aaggtaggcg attcactctg gctgactggt gtaaataaac cgatgcgtgt acgtgcgctg
     3301 catgcgcaaa accagccaac agaaaccgcc aatgccgggc agcgtatcgc gcttaacatc
     3361 gcgggtgatg cggaaaaaga gcagattaac cgtggcgact ggctgcttgc cgatgtgccg
     3421 ccagagccgt tcacacgggt gattgtcgag cttcaaaccc atacaccgct gacccagtgg
     3481 cagccgctgc atattcacca cgccgccagc cacgttacgg gacgcgtttc gctgctggaa
     3541 gataaccttg ccgagctggt gttcgacacg ccgctgtggc tggcggataa cgatcgctta
     3601 gtgctgcgcg atatctcggc ccgcaacacg ctggcggggg cgcgtgtggt gatgcttaac
     3661 ccgccgcgtc gcggtaaacg taagccggaa tatctgcaat ggctggcgtc tcttgcacgg
     3721 gcgcagagcg atgccgatgc gttatctgtt catctggaac gcggcgcggt taaccttgcg
     3781 gatttcgcct gggcgcgcca gctcaacggc gaagggatgc gcgaattgct gcaacagcct
     3841 ggctatattc aggctggtta tagcttgttg aatgcgccgg ttgccgctcg ctggcaacgg
     3901 aaaattctcg atacattagc gacttatcat gagcaacatc gcgatgaacc tgggcctggg
     3961 cgcgaacgtc tgcgacgtat ggcgttgcca atggaagatg aagcgctagt actgttgctg
     4021 attgaaaaga tgcgcgaaag cggcgacatc ctcagtcatc acggttggct gcatctgccg
     4081 gatcacaaag cgggcttcag cgaagagcag caggccatct ggcaaaaagc agagccgctg
     4141 tttggtgacg agccgtggtg ggtgcgtgat ctggcaaaag agacgggtac cgacgagcag
     4201 gcaatgcgcc tgacgctacg ccaggcggcg cagcaaggaa taattaccgc gatcgtcaaa
     4261 gatcgttatt accgtaacga tcggattgtc gaatttgcca atatgatccg cgatctcgat
     4321 caggagtgtg gttcaacctg cgcggcggat ttccgcgatc gcttaggcgt aggccgaaag
     4381 ctggcaattc agattctgga atattttgac cgcattggct ttacgcgtcg tcgtggaaat
     4441 gatcatttat tgcgcgacgc attattattt ccggaaaaat aaggaaatga ttaattaatt
     4501 tttaaaataa attaatacaa atttcttatg attttaaaaa gcacattgtt taatgaatac
     4561 aatgtgcttt ttattagatt aattttgata atcaataata atgatcatgt tttcgaatga
     4621 aaatcctcag taagctgccc accctttttt acactttcag gagtgtgtta tggcatcttc
     4681 aactttcttt attccttctg tgaatgtcat cggcgctgat tcattgactg atgcaatgaa
     4741 tatgatggca gattatggat ttacccgtac cttaattgtc actgacagta tgttaacgaa
     4801 attaggtatg gcgggcgatg tgcaaaaagc actggaagaa cgcaatattt ttagcgttat
     4861 ttatgatggc acccaaccta accccaccac ggaaaacgtc gccgcaggtt tgaaattact
     4921 taaagagaat aattgcgata gcgtgatctc cttaggcggt ggttctccac acgactgcgc
     4981 aaaaggtatt gcgctggtgg cagccaatgg cggcgatatt cgcgattacg aaggcgttga
     5041 ccgctctgca aaaccgcagc tgccgatgat cgccatcaat accacggcgg gtacggcctc
     5101 tgaaatgacc cgtttctgca tcatcactga cgaagcgcgt catatcaaaa tggcgattgt
     5161 tgataaacat gtcactccgc tgctttctgt caatgactcc tctctgatga ttggtatgcc
     5221 gaagtcactg accgccgcaa cgggtatgga tgccttaacg cacgctatcg aagcgtatgt
     5281 ttctattgcc gccacgccga tcactgacgc ttgtgcactg aaagccgtga ccatgattgc
     5341 cgaaaacctg ccgttagccg ttgaagatgg cagtaatgcg aaagcgcgtg aagcaatggc
     5401 ttatgcccag ttcctcgccg gtatggcgtt caataatgct tctctgggtt atgttcatgc
     5461 gatggcgcac cagctgggcg gtttctacaa cctgccacac ggtgtatgta acgccgtttt
     5521 gctgccgcat gttcaggtat tcaacagcaa agtcgccgcc gcacgtctgc gtgactgtgc
     5581 cgctgcaatg ggcgtgaacg tgacaggtaa aaacgatgcg gaaggtgctg aagcctgcat
     5641 taacgccatc cgtgaactgg cgaagaaagt ggatatcccg gcaggcctac gcgacctgaa
     5701 cgtgaaagaa gaagatttcg cggttctggc gactaatgcc ctgaaagatg cctgtggttt
     5761 tactaacccg atccaggcaa ctcacgaaga aattgtggcg atttatcgcg cagcgatgta
     5821 atcatcattt ccacaacggc tggcaaattg tcagccgctt tttcaactat ctctgtaacc
     5881 cttgcccgta aattcgtgat agctgtcgta aagctgttac cgactggcga agatttcgcc
     5941 agtcacgtct acccttgtta tacctcacac cgcaaggaga cgatcatgac caataatccc
     6001 ccttcagcac agattaagcc cggcgagtat ggtttccccc tcaagttaaa agcccgctat
     6061 gacaacttta ttggcggcga atgggtagcc cctgccgacg gcgagtatta ccagaatctg
     6121 acgccggtga ccgggcagct gctgtgcgaa gtggcgtctt cgggcaaacg agacatcgat
     6181 ctggcgctgg atgctgcgca caaagtgaaa gataaatggg cgcacacctc ggtgcaggat
     6241 cgcgcggcga ttctgtttaa gattgccgat cgaatggaac aaaacctcga gctgttagcg
     6301 acagctgaaa cctgggataa cggcaaaccc attcgcgaaa ccagtgctgc ggatgtaccg
     6361 ctggcgattg accatttccg ctatttcgcc tcgtgtattc gggcgcagga aggtgggatc
     6421 agtgaagttg atagcgaaac cgtggcctat catttccatg aaccgttagg cgtggtgggg
     6481 cagattatcc cgtggaactt cccgctgctg atggcgagct ggaaaatggc tcccgcgctg
     6541 gcggcgggca actgtgtggt gctgaaaccc gcacgtctta ccccgctttc tgtactgctg
     6601 ctaatggaaa tcgtcggtga tttactgccg ccgggcgtgg tgaacgtggt caacggcgca
     6661 ggtggggaaa ttggcgaata tctggcgacc tcgaaacgca tcgccaaagt ggcgtttacc
     6721 ggctcaacgg aagtgggcca acaaattatg caatacgcca cgcaaaacat tattccggtg
     6781 acgctggagc tgggcggcaa atcgccaaat atcttctttg ctgatgtgat ggatgaagaa
     6841 gatgcctttt tcgataaagc gctggaaggc tttgcactgt ttgcctttaa ccagggtgaa
     6901 gtttgcacct gtccgagtcg tgccttagtg caggagtcaa tctacgaacg ctttatggaa
     6961 cgcgccatcc gccgtgtcga aagcattcgc agcggtaacc cactcgacag cgtgacgcaa
     7021 atgggcgcgc aggtttctca cgggcaactg gaaaccatcc tcaactacat tgatatcggt
     7081 aaaaaagagg gcgcagacgt gctcaccggc gggcggcgca agctgctgga aggtgaactg
     7141 aaagacggct actacctcga accgacgatt ctgtttggtc agaacaatat gcgggtgttc
     7201 caggaggaga tttttggccc ggtgctggcg gtgaccacct tcaaaacgat ggaagaagcg
     7261 ctggagctgg cgaacgatac gcaatatggc ctgggcgcag gcgtctggag tcgtaacggt
     7321 aatctggcct ataagatggg gcgcggcatt caggccgggc gcgtgtggac caactgctat
     7381 cacgcttacc cggcacatgc tgcgtttggt ggctacaaac aatcaggtat cggtcgcgaa
     7441 acccacaaga tgatgctgga gcattaccag caaaccaagt gcctgctggt gagctactcg
     7501 gataaaccgt tggggctgtt ctgatataag aagctggtcg cattgggtat tcattgcctg
     7561 atgcgacgct tacgcgtctt atcatgccta cgggaacctg accgtaggcc ggataaggcg
     7621 tacacgccgc atccggcata aacaaagcgc acgttgttac aatttacgtt ttaaacctac
     7681 gtgcgcaata acccagacta cgccaacaga agtgcgtttc tggggcgtgt tttgtcagga
     7741 gtttaatctc gcgtttcgat ggtgagcggg cgaatcaggc cgtaaatcac cattggtgat
     7801 ccgaggccaa tcagcaataa acggtagata attgaaggtt taatacgctt aatctgtact
     7861 gtggatgttt tactggagtt attcattagt ttggccaata gttccattat ttcaatatga
     7921 taagtctcga cctgttgaaa agccaggtag cacacttcag aaagtatata aaaaacaata
     7981 tgtcgttata taaataagga aattgcactg catcatggca tttcataata tgcgttaatt
     8041 gttctttttt atattctctg agggaaatat gttcctggac tattttgcac tgggagtgct
     8101 tatttttgta tttctggtga tcttctatgg gattattatt ttacatgata ttccctacct
     8161 gattgctaaa aaacgtaatc atcctcatgc cgacgccatt catgttgctg gttgggtgag
     8221 tctttttacg ttacatgtta tctggccatt tttgtggatt tgggccacgc tttaccgccc
     8281 ggagcgggga tggggaatgc aaaaccatga ctcctccgtt gtgcagctac aacagcgtat
     8341 tgccgggctg gagaaacagc tcgccgacat caaatcctct tctgccgagt aatacttatg
     8401 gatttactga ttattttgac ctatgtggct ttcgcatggg caatgtttaa gatcttcaaa
     8461 attcctgtaa ataaatggac cattcccaca gcggccctgg gtggcatatt tattgtcagt
     8521 ggtttaattc tgttaatgaa ctataaccat ccgtatacct tcaaagcgca aaaagcggtt
     8581 atttctattc ctgttgtccc acaggtgaca ggcgtggtga tcgaagtgac ggataagaaa
     8641 aatacgctga ttaaaaaagg tgaggtgcta tttcgactgg acccgacgcg ttatcaggcg
     8701 cgggtggatc ggctgatggc ggatatcgtt accgcagaac ataaacagcg ggcgttgggc
     8761 gcagagttag atgagatggc ggcgaatact cagcaggcaa aggccacgcg ggataaattc
     8821 gctaaagagt atcagcgtta cgcacgcggc agccaggcga aagtaaaccc gttttcagaa
     8881 cgcgatattg atgtggcgcg gcaaaattat ctggcgcagg aagcctccgt aaagtcatcg
     8941 gcggcggaac aaaaacagat ccagagccag ctggatagcc tggtgttggg tgaacattct
     9001 caaatcgcca gcctgaaagc gcagctcgcg gaagcaaaat ataaccttga gcagacgata
     9061 gtgcgtgcgc cgagcgatgg ttatgtgacc caggtgctga ttcgtccggg tacctatgcc
     9121 gcgtcgctgc cgctacgtcc ggtgatggtg tttatacccg atcagaaacg acaaattgtg
     9181 gcgcagttcc gtcagaactc cttgctgcga ctggcccctg gcgatgatgc ggaagtggta
     9241 tttaacgctc tgccaggtaa ggtattcagc ggcaagctgg cagccattag tccagctgtt
     9301 cccggcggag cttatcagtc gaccggcacc ttacagacgt taaacacagc gccgggttca
     9361 gatggcgtta tcgcgaccat tgaactggat gagcacactg atttgagcgc tttaccagac
     9421 ggtatttacg cccaggtggc ggtctactct gatcatttca gccatgtctc ggtgatgcgc
     9481 aaagtgctgt tacgcatgac cagttgggtg cattaccttt atctcgatca ttaatcttcg
     9541 ctttccgccg cttgttcagg ccgcagttgc tgcgactgag caagctggtg gcgaatttca
     9601 cgcagcattt catccagcac atactggacc cgccagggct ggtattcccg tttacggaag
     9661 atagccacca gatccagcca ccattcatac gggtgctgaa agcagggcac cagcgtgccg
     9721 tcttgcaggt cgctctgcac acttttgtct ggcgcaaaca caatccccag gtgatttcgt
     9781 gccagctcca gcgccgattg cgtgttatcg caaacgtaat ttcccttcac gcgataatcc
     9841 cgcacctctt tactcccggc gacgttgaag cgccagatat tcgcgtcgtc aatcatcatc
     9901 gagtcgatca aaatacagga gtgatgttcg agttcgtcag gacggctaat aggatgtttc
     9961 tcaagatagc gctggctggc ataagcggtt acggcatatt gggtaataaa actggcaacc
    10021 agcgattcat cttttggtgg agcgtagctg attaaaacat cacaatcatc aggaaattcg
    10081 acgccttcat aaaaggcatt acgctcaaga ttgcaggttt ttagcgataa ggtgatatca
    10141 ccgatatctt taattttatc gattacatgt ttggataaat aggtaattat gccggttggg
    10201 gcgtagatag tgacccgacc acgtttctca tgcttataat ctgcaataaa attattaagt
    10261 tgctcgtttc tatccagcat gtcgttgatg tacggtaaca gcgcggtgcc aaaaggtgtg
    10321 agcatcagct gccgggtggt tcggtcaaag acttttaaac ccacttttga ttcaaaatca
    10381 gcaagatatt tgctgacgtt ggcctgtgcg atgccaagta cagtcgcggc atggctgata
    10441 ttttcactgg cagcgattac cgagataatt tttaactccc ggtacttaag ttgtaatttt
    10501 gtcatcgcaa cagcccaatt atatataatt ttatatatta ctatataaat atgaatcttg
    10561 caccggagaa attgtaagca ttactatgcc gactcttttt tatcttattt taaaatggaa
    10621 taccggacat gttaattaac cgcaatattg tggcgttatt tgcgttgcct tttatggcaa
    10681 gcgcaactgc ttctgaatta tccattggtg ccggtgcggc ttataatgaa tcgccttatc
    10741 gcggttataa tgaaaataca aaggcaattc ccctgattag ttatgaaggt gattcttttt
    10801 atgttcgtca gaccacgtta ggttttattc tgtcgcaaag tgaaaaaaat gaacttagcc
    10861 tgaccgcatc ctggatgccg ctggaatttg accctgccga taatgacgat catgccatgc
    10921 aacaagttga taagcgtgat agtacggcta tggcgggggt tgcctggtat caccacgagc
    10981 gttggggaac cgtgaaagcc tctgcagctg cggacgttct ggataacagc aacggctggg
    11041 tgggggagct atcggttttc cacaaaatgc agataggtcg cctgtcgctg acacctgcgc
    11101 tgggcgttct ctattatgac gagaatttca gtgactatta ctatggcatt tcagagagtg
    11161 agtcccgtcg tagcggtctg gcaagttatt ccgcgcagga tgcctgggtg ccctatgtca
    11221 gcctgacggc aaaatacccg ataggagagc acgtagtatt gatggcgagc gccggataca
    11281 gcgagctgcc ggaagagatt accgacagcc cgatgattga tcgtaatgag agttttacct
    11341 ttgtcaccgg cgtgagctgg cgtttttaat tcaccggtgg atgtcggtgc ggctggtgct
    11401 ccgtcgtaat gccacaaagg ttgttgctct ggattgctct gttcataccg ggaacctggc
    11461 gtctgaatca ggatcttatg gctgaacaat cccttgcctt caaatgtcgt aaatggcgca
    11521 tcggcgggca gcaacaggtt atgcagtgac tcgacgttgt cggcctgctc catgcaatac
    11581 ggtttaatga ggttggctat ttccggcaga tttttcgcaa gcacaccggt ttaacgccag
    11641 cagcgtggaa gcggcgttac agcaaggaac atatcaattc gtagtgccgg ggcgatgaag
    11701 ccccggcgtg agggattact gcccgtaata ggcattggcc ccatgcttac gcaggtagtg
    11761 cttatccagc agttcgtttt gcatcgcagg gagctgcggc gcaagctggc gcgagaatag
    11821 gcccatatag gcgcattctt cgagtactac ggcgttatgc acggcatcgg cggcgttttt
    11881 accccatgcg aacgggccgt gagaatgcac cagcaccgcc gggatttgtg ccggactcct
    11941 gccacgttct tcgaaggttt caatgatcac ttcgccggtc tgatattcat attcgccgtt
    12001 aatctcctct gcggtcatct gtcgcgtgca ggggatggca ccatagaaat aatcagcgtg
    12061 cgtggtgccc caggcgggga gatccagccc ggcctgcgac cagatggtgg cgtggcgtga
    12121 gtgggtatgc acaatgccac cgatttcggc gtagcgacgg taaagcgcca gatgcgttgg
    12181 cgtgtcggac gagggctttt tgctaccttc caccaccttg ccgctggcta tctcaaccac
    12241 caccatatcg tcggcggtca tcacgtcata ctcgacgccg gaaggtttga ttaccatcca
    12301 ttgccgcgtt tcgtctaccg cgctgacatt gccccaggtg aacgtcacca gatggtgagc
    12361 gggaagcgcc agattcgccg ccagcacgtc ggctttcagt tgctctaaca tataaatcca
    12421 gcctcctgca tacgcgcttc aatccaacgc cgcgcctgaa taatctccag caccggctct
    12481 ttggcttttt cggtccacat ctcaatcagg aaagaaccgc gatagttcag tttatgcagc
    12541 gttttgaaga tgccaacgaa atcgacgcag ccttcgccaa acggcacgtc gcggaactgt
    12601 ccgggacttt gctcggtaac tggctgggtg tctttcaggt ggatcgcggc gatacggtca
    12661 atgcccagtt tcagttcggc gggaacatca ttgccccagg cgctgaggtt gccgacgtcc
    12721 gggtagacgg tgaaccacgg cgaggcgagc atctcgtccc actttttcca tttactgatg
    12781 gagttcataa acgcggtgtc catcatctcc accgctagca tgacttgtga tgccgccgcc
    12841 tgttcgaccg cccacgccag cccttcagca aaacgttgcc gggtgccttc atcgtggtct
    12901 tcgtaataga cgtcgtagcc cgccagctgg atggtgcgta tgccgagatc gcgtgccaga
    12961 cgaatcgctt tgctcatgat ctcccgtgct cgctggcgta ccgcgtcgtc acggctacca
    13021 aaaggaaagc gacgatgtgc ggacaggcac atcgacggga tcccaacacc cgtttcgatc
    13081 atcgcggcaa ccagcgaagt cctttgtgcg gtgctccagt caagacgtga aagccgttcg
    13141 tcggtttcat ccaccgacat ttcgacaaaa tcaaaaccgc agctttttgc cagcaccagc
    13201 cgctccggcc aggagagatc tttcgccagc gccttttcat aaatccctaa cggatgatta
    13261 cgcacgcttg cctccccaga tagcgtcgat ttgcgcatgg aaatcgccag ccacctgcgc
    13321 cggatttgct gagcctgcca gtgctcgccc ggcaataaac gctttcacgc gaatatcttt
    13381 aaacagcggc aggtcagcag gggtaatccc gccggtaatg gaaagctcaa ggccgatatc
    13441 ggaaagcgcc ttcatgcgtg ccagatcggc ttcgccccac tgttgcccgc tggcctgtgc
    13501 atcacgaccg cgatgataaa tcgcctgccg cacgccaata cgatgccagt cgcgggcgtc
    13561 gtccagcgtc cagttaccga acagctcgat ctgaatttca ccaccgcagc gttgcgccat
    13621 cgcgtggcct ttttccaccg tcgcgagcgg tgcggcgcag atgatggtca tccagttagc
    13681 gcctgcgcca aatgcctgtt gcgcgagcgt ttcaccagcg tcggcgacct tccagtcggc
    13741 aacgatgatt ttgtcagggc actgttcgcg caaggctttc accgcgccaa gcccttcgtt
    13801 taaacagaga atggtgcccg cttcgacaat atcgacgctg tcttttaact gcgtcacgtc
    13861 gcgctgtgcg gcttcaagtg atgagtggtc gagtgccagt tgcagaagtg gtcggctcat
    13921 aatatgtgct ccttgatgcg ggcgtgaaag ccctgaagtg cggcaatgag atgctgatag
    13981 cgttggtatt tttgttggta aagctgatgg gcggtcatat ccggcagcag ggtgcgtacc
    14041 gggtgctgta agtcacgttg agcttcgctg aaatcgcgat aaactccggt gccgacacgg
    14101 gcggcaagtg ccgcgccaaa acagccggtt tcttccacct gcggcagctc gatacgcaga
    14161 ccgctgacgt ccgccagcat ttgcatccag acatcggagt gcgccgggcc gccagtgacg
    14221 cgcagggtgt gcacatcagt aaaacgttcg cgcatccggt tgaggtgggt catatggctg
    14281 aacacccccc cttcataaat ggcctgcaac aggtgtgcgc gggtgtgaat ggcctgcatc
    14341 ccgtagaaac cgctggtcat ctcgagtccg gcgttgctgc cgtacaggaa cggcaggaaa
    14401 aagagatcgc caccggcctt cggcaagctg gcaacggcct ggttgatctc atcaaacgag
    14461 atttctcccc actgtgcggt aaaccattcg aggttgccgg aagaggtggg gctggcttcg
    14521 tgaacgataa attcaccatc gttaacgtag cgaccataga catacggatg cgcttcaccg
    14581 tcacgtaaac cgcgggttat gccgctggtc accgcccagg tgcccatcac cgcattaagg
    14641 gtaaattcgt cttcgatccc ggcgcagagt gcggtggaaa ccacatcaaa caggccgccg
    14701 acaacgggcg tacccgcttt cagaccggtc agtacggctg tctgagcggt gatctccccg
    14761 cagatttcgg cagatccgac aacaggcggc agggcgtgat tgatttcagc aatccccagc
    14821 cagtcggtga ggcacgggtc atattcccca agactcatgt tgtagagatt ggactcggaa
    14881 atattgctct cttcacagcc tttgacgccg gttaaacacc agcgcaggta gtcgtgcgtc
    14941 atcatcacgc agccaatttg cgcgtagcgt tccggttcgt gctctttaag ccaacgtaac
    15001 agcgataccg gatgcccggt ccacaaggtt tgtcgggtca gcgggtagag tttttccggg
    15061 atgccatctt cctgccagcg acgaacgatt tccatcgccc ggcgatccga ggataaaatg
    15121 gcgttaccga gcggcttgtt gtttttatcc agcaaaaaca agccttttcc ttgtgcggag
    15181 ataccgatac cgacaatttg ttccccgcta acgccggaat gggtaagcag ttcgcgaatg
    15241 acagccatgc agcattgcca cagttctgcc atatcgcgct ctgcccaacc tggctgcggg
    15301 cttaatgcgc acagcggcag gcgctgcacg cctgcctccc ggccttcgcg gtcatacagc
    15361 ccggctttca gccagctacc gccacaatct aaccccagcc agtattgcgt catggtttat
    15421 tgcacctcat ccacggcttt cagtagatca gcaccctgcg gaacatcttt tacaaacatg
    15481 tcgcgaacct gattacccag agcgtcgcta aaggctttgc ggtcgagatc ggtgatgact
    15541 tccacgcccg cttctttcat gccgtcgatg attttttgct gatcttcggc aaccagtttg
    15601 cgctggtagt tacccgcttc ctgcgcagat gaaattagcg cttgctggaa ctccgggctt
    15661 aagccatcaa acttcgcttt gttgatcacc accagaagcg gggaataggc gtggtgcgtc
    15721 agagaaaggt acttctgcac ttcgaaaaat tttgctgacc agacgacgtt gatcgggtgt
    15781 tcctgagcgt cgatagtgcg ggtttccagc ccggtataga cttcggcaaa cggcatcggg
    15841 atcgggttag cgccaaagac tttgaatgcg gcgatattca tcgggctatt gttggtgcga
    15901 attttcagcc ctttcaggtc ggcgggggtt ttaaccggtg cgcgcgagtt ggtgacatcg
    15961 cgccagccgt tttcccagta ggccagtact tttagtcctt taccttcaag tgaggctttc
    16021 agatcatcac cgactttgcc gtcgagcgtt ttatgcgcgt gagcggtatc gcggaacagg
    16081 aaagggacat caagcaagtt catcactggt gataacccgg caaagttatt cgagccggac
    16141 atttccatat cgatggtgcc gccacgtacg ccgctgatca tcgcctgcgc gttaccgagg
    16201 gtgctatccg gaaacaattt taatttcagc tcgcctttgg ttctctcctg caataaatca
    16261 ttgaattttt tcgccgcaat atgttgcgag tcggtttgtg aggtttcata accgaaacgt
    16321 aaagattgcg ccgccagaga agatgtgctg aatgcagcca ggccagcaat gaataatgcg
    16381 taggttacag agcgtaattt cataatattt tccttttaat taatccattt caaagggagg
    16441 atgatgagat cgggaataaa aacaaatacg actaataatg aatataaaac caggacgtaa
    16501 gggaaaacgc ctctgactgc atcatcgaat ttgagttttg ccacccctga aataacgtta
    16561 agtacattac cgataggcgg tgtaattaag ccgattgagc agttaatgat aaacatgaca
    16621 ccgaaataaa tcggatcgat tcctgcctct ttaactaaag gcattaatac cggggtaaga
    16681 attaataccg tcggcgttaa atccatgacc atgccgacaa tcaggatagc caccataatg
    16741 acgataaaca gcagacgcgg tgaatcgacc aacggttgca gtaaatcaga aaccatcatc
    16801 ggcagttcag caatggtaat cagccaggcg gaaacttgtg ccgaggccac cagaaacata
    16861 accactgagg tggttttcgc cgcgccaatg agtacatgcc aaagtgtggc gaaggtcatt
    16921 tcacggtaaa taactgtggc gacaaacagc gcatagaaag cagcaacggc cccggcttcg
    16981 gtaggggtaa acagaccgga gcgaaacccg ccaataatga tgactggaag aaacagcgcc
    17041 cagataccgg agacaaaaga gtgccagatt tcctgcatcg ttgctttttg ctggcggggt
    17101 aaattaaggc gactggcctg ccaccaccag gtaagcatca gcgttgcgcc catcatcatg
    17161 ccaggggcaa tgcccgccat aaacagctta ctgatggata atccgctgga aacgccgaag
    17221 ataataaacg gaatggaagg gggaataatt ggcgcgataa tgccgccaga ggcaatcagc
    17281 cccgccgccc ggttgaccgg gtagttggcg ctgcgcatca tcggcaccag tagagcggca
    17341 acggcggcgg tatccgcaac ggcagaacca gaaaggctcg ccataatcat agctgccagc
    17401 acgccgacgt agcccagccc gcctggttta tgccccacca gtttcatcgg caggtcaaca
    17461 atgcgttttg acaagccgcc cgcattcatg atttcacccg ccagcacaaa gaacggaatc
    17521 gccagcaggg agaagctatc ggctccgttc accagcgttt gtgccatgat ctggacatca
    17581 aacatgtcca gccagaacat taacgccgcc ccgcacaaca acagtgccca ggcaataggc
    17641 aaaccgatag caataccacc caacagacag cccagaaaaa tcagcacagc catgattaag
    17701 ctccttgcgg tggcgacgtt agagaattgc tacgcgtgat gagttgatat aaatgacgca
    17761 gttcaaagaa tgcgataacg aggctggtgg gcagacaagc ggcatacatc aggccgatgg
    17821 gtaaaccgag gatcggtgaa taatcgctcc agtcctgaat tgtttttagc gttgcgcccc
    17881 aggccagtgc gccacaaata aataagatta aggaatgggt aaccagagcg actcgtcgtt
    17941 gccatgcggg ggagagtttc tccaccagaa aggtgacctg aacgtgggcg ttatccataa
    18001 aagccacaat cgcgccaata aatgttaacc agacaaataa ataacgtgac aattcatcta
    18061 cagataaaat gcttgtctga aaaccatatc ttaaaataat gtttataaac acaatacagg
    18121 aaagtacggc gagattaatc gccagtattg cttcaagtat ttttttcata gctattcctt
    18181 gaggctatgt ctgtcataat tcaagttgca tgtgcagcaa cctaaattat taatatagtt
    18241 agagcaataa cattacccag tcgttctggc gtagacgatt attcgattaa ttcagcgccg
    18301 ttaatgcgac tttaaccaca atttttcgta tctcagaggc tgtttgcaaa atacaacctg
    18361 gtcggtgaac atcctgcgga aagaaaattg cgtagctgcc cggtatcatt tctataaatg
    18421 attcatgttc actgtcatga taaaaaataa tatcgcgctg ctctaatagt gattcgctga
    18481 ctttattatt tcccgtatca atagcaatgc cgattttctc ttcaccccac gccagaaact
    18541 gaatatcgat ataccgacga tgcacttccg gacggttttc caccgcttcg cgtgtggtta
    18601 aatcgataat ttgcgcataa atatttttgc cgtcgatttc gacaacgccc ggctccaggg
    18661 cgttgaaatc ggtagcgcgc agaaaatcga gcgccttttc aatggcggcg ggcaaacggc
    18721 acggattggg ctgcgcgata tgtccaaaaa tcatgactta tctccttata acgcctggat
    18781 tttggcccac acgctgtcat caacggtaat accgttacgg cggttttcgg ccagcagggt
    18841 agtaaattcg tggccgggta agcggatggc ctgattttcg tcagcgcgtt cagcggtagt
    18901 aacgtaatcc atgatacgtt gcagcttggc atcgcgggtg ggaccgtcga taagcttgtc
    18961 cacttcaatg gcaataaaaa tttgtgaaat gccgtattcg tcgctgttgt cctgggtgac
    19021 ttcggcaacc gatgcgccgt cggaaaggag agtagcgatc atatccagca caatcgacat
    19081 gccagaacct ttccagtagc ccatcggcaa aatgcggcga ttcttctcga taacgccagg
    19141 ttctttggtc aaattgccct catcatcaaa gccaccatcg accgggagct gacggcccgc
    19201 caggcggtta acttctaaca tgccgtaaga gaacatcgac atcgacatat cgaccatggt
    19261 gatcggcgtg gaaggaatgg cgacgatcag cgggttagtg ccaatgcgac actcttttgc
    19321 gccccacggc ggcattacgg cgatggagtt ggtccagcaa atgccaatat agcctttttc
    19381 cgccgcctgc cagccgtagc tgccgccgcg catccagtgg ttggcattac gaagtgccac
    19441 cagaccaata ccgtgatcgg cagccagttc aatggcgcga tccatcatct ttttcgccgt
    19501 caggttgccg atcgaacgct gggcatccca ctgttcaatt gcgccgaggc tggttatacg
    19561 tttgggttgg gcatcaggaa tgatatcgcc gttttccagt tgttgaatga aacgagggaa
    19621 acgattaacg ccgtgagaat aaacgccgga ttcggtggtg cgggcgaaca tctctgcaca
    19681 ggcgtcagcc gtttcgctgt caacgccgcg tgaaattaag acccgattaa aggctgcttt
    19741 taactgctca aatgtcactt tcatcccagg cttccttgtt tttttgatcg cttttttggc
    19801 ttaaaatttc aatatgcgaa acttgatttc aaatatatcg atcgcttttt aacaaagcaa
    19861 tctgattgat gaatttcaaa agacataaaa atcaagtggt tataaattat ctgtcgagat
    19921 cgtgaactac ggcacacttt gcgctaccat caggacgcga caaaatgggg aaagaagtga
    19981 tgggaaaaaa agagaacgag atggcgcagg aaaaagagcg tccagccgga agccagagtc
    20041 tgtttcgcgg gttgatgctg attgagattt tgagcaacta tccaaacggt tgtccgttgg
    20101 cgcatctttc ggagctggct ggtttaaata agagtaccgt ccatcgctta ttgcagggat
    20161 tacagtcctg cggctatgtg accaccgcgc ccgccgcagg gagttaccgc ctgactacca
    20221 aatttattgc cgtcgggcag aaggcgctgt cttcgctgaa tatcattcat atcgccgctc
    20281 cgcatcttga ggcactgaac atcgccactg gtgaaaccat taacttctcc agccgcgaag
    20341 acgatcacgc tattttgatt tataagctgg aacccacaac cgggatgctg cgaacccgtg
    20401 cctatattgg ccagcatatg ccgctctact gttccgcaat gggcaagatc tacatggcgt
    20461 ttggtcaccc ggactacgtg aagtcatact gggaaaacca tcagcatgag atccagccgt
    20521 taacccgcaa taccattacc gagctgcccg cgatgttcga cgaactggcg cacattcgtg
    20581 aaagcggagc ggcgatggac agagaagaaa acgaactcgg cgtctcctgt attgctgttc
    20641 cggtgtttaa tattcatggg cgggtgccgt acgccgtgtc gatttcgctt tcgacatcac
    20701 gtctgaaaca ggtgggggag aaaaatctcc tgaaaccact gcgtgaaacc gcgcaggcta
    20761 tttctaatga actgggattt actgtcaggg acgaccaggg cgcgatcaca taacgctttg
    20821 gacaagtgcc aaaactttaa catttccttc gttggatcaa agcagtaggg acgcgctctc
    20881 tggcactctg ctgttttagt gcaaaggagt gatcatgaac cggtttatta ttgcggatgc
    20941 gacgaaatgt atcggttgcc gtacctgtga agtggcttgc gcagtgtcgc atcaggagaa
    21001 tcaggattgc gctgcgttgt caccagacga gtttatttcc cgtattcgtg tcattaaaga
    21061 ccacagctgg accacggcag tagcctgtca tcagtgtgaa gatgcaccgt gcgcgaatgt
    21121 ctgccctgtt aacgcgataa gccgcgaaca tgggcatatt ttcgttgaac aaacacgttg
    21181 cattggctgt aaaagctgta tgctggcttg cccgtttggt gcgatggagg tcgtttcttc
    21241 gcgcaaaaag gcgagggcga ttaagtgcga tctgtgctgg catcgggaga cggggccggc
    21301 ctgtgttgaa gcctgcccga caaaggcgtt gcagtgcatg gatgtcgaga aagtgcagcg
    21361 gcatcggcta cggcagcagc ctgtttgaaa cgtttttccg gcgtttctca acgccggaat
    21421 agtgcgcttt gtttatgcca gatgcggcgt aaacgcctta tccggcccac aaattcttgc
    21481 aaattcaata tattgcagaa atcatgtagg cctaataagc gtagcgcatc aggcaatttt
    21541 tagtgacttt cagcccaggc tctttctatc tcttccgcca gaatcttcac ccccgcctca
    21601 attttctccg gctctggtac gtagttcatg cgcatacatt gatgcgtatg cggccacggt
    21661 ttgtccagcc ctgggaagaa gttgtgcccc ggcaccatca gcacgccgcg tgctttcagg
    21721 cgctgataga gctgctcggt cgtaatgggc aaatccttaa accaaagcca gaggaaaatg
    21781 gctccttctg gtttatgaat taggcagcga tcttccggta aatagcggcg aatgatggcg
    21841 atagtttcct gaacacgctg gtagtaaaac ggtttgatga ctgtttcaga caggcgcagc
    21901 agatcgttac gcttaatcat ttcacacatc atcgccggac caataccgcc aggtgccagg
    21961 ctgataatgc cgttcatatt ggtgatggca gtgatgattt tttcattggc gatgataatg
    22021 ccgcagcggg agccaggcag ccccagcttg gaaagactca tgcacagcac gatattcgga
    22081 ttccatagcg ggcgcgcttc actgaagatg atacccggga acgggacgcc ataagcgtta
    22141 tcaatcacca gcggaatgcc gtgttgattc gccagcgcgt caagcttcag caactcttcg
    22201 tcagtaatca cattgcctgt tggattcgtc ggccgggaga cgcaaatcat cccggtttct
    22261 tcgccaatat gcagatgctc aaaatcgacg tggtatttaa actggccttc cggcagcagt
    22321 tcaatattcg gacgcgcaga gacaaacaga tcttcttcca gtccggcgtc agcgtagcca
    22381 atgtattccg gtgccagcgg gaacagcact tttttgaccc gaccatcggc acggcgtccg
    22441 gcaaacagat taaataagta gaaaaacgcg ctctggctgc cgtttgttag tgcaatattc
    22501 tgtgcttcga tatcccaacc caacttctcg cgcagcattc cggcaagcag tgtgagtagc
    22561 tccgttttcc cctgtggacc gtcgtaattg cacagtgcat cagtcgcttt gccactttcc
    22621 agcatgtcgg tcagtagcgt ctggaagtag tcctgcattt ccgggatctg cgccggatta
    22681 ccgccaccga gcataatcgc gccaggcgtg cgtaaaccgt cgttcagatc ttccatcagc
    22741 agcgtaatgc cggagtggcg ggtaaatttg tcaccaaaaa gggagaatgt catagcggga
    22801 tatctgtcga actctgtagc aaggaaggta acaataacgc tacatttgct ggggtgcaaa
    22861 tcggtctgtt ggagagtgag cggtgcttta tcctgcaacg ctgattaggg ctgacatttt
    22921 atcctggttg gcggcttccc gaggtactga cgaacgggaa gccggaaaag tcactgttgc
    22981 ccagcccaga tgaccagcac tttatcgtcg ccatgctcac gaacaaagcc gtagccctgc
    23041 ttcagcgaaa gtgtcgtttg tttgcccgcg ccaattgcgg gatggcgggc gcggaactgg
    23101 ctgattttct gccagtgcgc gacgttggcg gcagatttac cgctaacatc ctgccagttc
    23161 atatccgaac gtgtaccttg cagcggatca gaacctgtag gaccgaacgg acgcgaggat
    23221 tcatcgccat aaaagatttg taccgcgcct ggcgctaata gtaataactc tgctgctttg
    23281 tcgccccctt cacggaacag acgggtatca tgcgacgaga ggtagctcaa cacgttgaaa
    23341 ccctgcaatt tctccgccat ttgctgccag gtcgtatcca tctgcgccag acaatcgact
    23401 gctttcgccg cctgctcctg ataatcgaaa ttgatcatcg catcgaagcc gtggcgatag
    23461 tagtcacttt gcatcacgcc gtggccccag gcttcaccgg tcatccagaa aggtttgtca
    23521 tctaatgctt tgtcggggtt agcttttttc cattcgcgaa gcgcggcgct ggcttcggtt
    23581 ttcagttgct gccaggcggg caactcaaca tgtttggcgg tatcgacccg aaaaccatca
    23641 atcccatagt cgcggaccca ctgacttaac cagtgggtta agtaatcgcg aggtgtaaag
    23701 ccttcgatga ctttagcgtg agtatccgtt ttgtttttat agaacaccgg cagaccagaa
    23761 gcggtagttg attcggtttt gatatccggc aaaaaggcca gcgacatagt gagatcgtcg
    23821 aatccaggat tgtcgtaatc gccgatatcc gttctgatcc agttttttcc ccaccattta
    23881 tcccagcctg ttttgtcgct gaaattaatg taatcgttaa agctatgcca ggtttgcccg
    23941 gcggcaggtt tccagtcgct ccagcgttca cccagcgttt ttttcacctc gtcaccagaa
    24001 agatataacg cgccaaactg atactcctgc atatccgcca gcgtggcata gccggtgtgg
    24061 ttcatcacga catcaaagag aatacgaata ccgcgctgat gtgcgctatc aaccagcgtc
    24121 cgtagatcgg cttcgttgcc catattggca tcaagattcg tccagtcctg tgtgtaataa
    24181 ccgtggtagg cataatgcgg gaaatcgcct tttgtaccgc cgccgaccca gccgtgaatt
    24241 tgctcaaatg gggcgcttat ccataaagca ttaacgccca actgctggag gtaatccagt
    24301 ttgttggtca ggccgcgtaa atcgccgccg tgaaaagtgc caatttccgc cataccgtct
    24361 ttatgacgtc cgtaactctg gtcattactg ggatcgccgt tttcgaaacg atctgtcagc
    24421 acaaagtaaa ccgtggcgtt atgccagtcg aaaggggcag gggcgtcagt ttctgcccgt
    24481 tccagcagga gtaaaccgtt gctggtagca gcgggttgta acgttatttg accgttcttc
    24541 actatcgcaa tttgctggct gtaataatcc cgtacggcgg ctccttccgg gaaagtggcg
    24601 ctgacatcca gcgtgagcgg taatccatcc catttcgggc attcacggac caggtttgct
    24661 accggttcgg cggcgttctg gatggaaatc atcaatgttg gcgtaccgga gcgggtgtct
    24721 atttgcagcg tatatttgcc gtctctgaac aatcgccatt gaggcggcgt gttgctacaa
    24781 ggttgcaggg aaagcatctg attgagtttt atcgcatctg caggctgcca gcactgttgg
    24841 tcaaaattta gcgtgagtgg acgcgtacct ttgggcaact gcgcgtggct gacaaatgtt
    24901 cccgttccct gttcgctaaa ggcagggaac cccggagaag tccagctggc ggcaacggcg
    24961 aagccaggaa ggagtgtcag aaaacaggcg gcgagtttca tggtggatga gtccttattg
    25021 ctgcgatttc agacagtttg ccagcgataa gccagacaaa actcatccct gagcggtaag
    25081 tccacaggat gagaagcaag ggtgagcgat ctcgcgcaaa aaacggctga attttgcgat
    25141 aactcccaca ttttctgcga tttagcgcca atctgaatcg ttaacacgtg acatagtttc
    25201 agatttggac tattccttgg ggtgctcttg acagctattt ttgatatgat ttgagattca
    25261 actctcaaat ttgtgaaaaa tataaggtgt tggaatgatt aaatccgacc aggagacctg
    25321 atgattttga ctcccatacg acgatatggg gcgatgattc ttatgttact cactctggtg
    25381 ttttcgagtg aggtgttagc gaagacgcac acaacaacag cgagtcaaaa gtcccactta
    25441 actaaagcta gtaataaaca ggtaagcagt aaacaagagt attctcgcaa tagtgcaaag
    25501 agtagttcac ttcctgattt gcgaaaatac ccttccggaa caccaaggaa aaaggcgttt
    25561 ctccggaccg taatgcctta cattaccagc caaaatgcag ccattactgc agaacgtaac
    25621 tggctgattt caaaacagta tcagggccaa tggtcacctg ctgagcgtgc gcgtctgaaa
    25681 gacatcgcca aacgctacaa ggtgaagtgg tctggtaata cgcgaaaaat cccgtggaat
    25741 accttgcttg aacgcgtaga cattatccct accagtatgg tggcgacgat ggctgcagca
    25801 gaaagcggtt ggggaacgtc gaagctggcg cgcaacaata acaatctgtt cggcatgaaa
    25861 tgcatgaaag gacgttgtac caatgcgccg ggtaaagtga aagggtactc acagtttagt
    25921 tctgtcaaag aatcggtgag cgcctatgtc actaacctga atacgcaccc ggcttactct
    25981 tcgttccgta aatcgcgtgc gcagctgcgt aaagcggatc aggaagtgac tgccacagcg
    26041 atgattcaca agctgaaggg ctactcgacc aaagggaaga gttataataa ctacctgttc
    26101 gcaatgtacc aggataacca acggttaatc gcggcgcata tgtaattgca tttccttgag
    26161 ccttatctga tttgtcggtc ggataaggct tttgctcgca tcaggtggct gtgctgagtt
    26221 ccctgatgtg acgccgacaa ttctcatcat cgctacaaca tgatctcgct atttacatcg
    26281 cgatactctt ttggcgttgt gtcatatgct tttttaaaaa cagagtagaa atattgcagc
    26341 gatggataac cgcacatttg cgatatctca ttgatcgaca aggtggttga aatcagcaga
    26401 ctgcgcgctt tctccagctt ctcggcatga atcatggcat ggatggtttc acccacctct
    26461 tctttaaaac gcttctcaag attggagcgc gagatcccga ccgcatccag tacctgatcc
    26521 actttaatcc ctttacaggc gtgattacga atgtaatgca tggcctgaat aacggcggga
    26581 tcggtcagcg agcgataatc tgttgagcgc cgttcaatga cgcgaactgg tgggaccaaa
    26641 attcgctgta gcggcatttc ttctttatct aataatcgat gcaacagttt tgccgcctga
    26701 tagcccattt gccgcgcgcc ctgagcgacc gaagaaaggg cgacacgcga cagatagcgg
    26761 gtcagttctt cgttatcgat gccaatcacg cataattttt ccggtacggg aatatgtaga
    26821 tgttcacata cttgcagaat atgccgcgcc cgggcgtcag taacggcaat aatcccggtt
    26881 tgcggtggca gcgtttgtag ccagtctgcc agccgatttt gcgcatgttg ccagttctct
    26941 ggcgcggttt ctaacccctg ataaaccact ccgcgatact tttcttcggc gacaagctga
    27001 cgaaatgcat attcgcgttc agtggcccaa cgtttgccgc ttgattccgg aagaccataa
    27061 aaagaaaagc ggttaacgcc tttctctttt aaatgcaaaa atgcgctttc aaccagcgca
    27121 tagttatcgg tggcaatgta atgaacgggt gggtaacttt ctgcaaggtg atacgagccg
    27181 ccaaccccaa caatggggac gtcgacatca gccagcgctt gctcgatctg tttgtcgtcg
    27241 aagtcggcaa tgacgccatc tcctaaccag tccttgattt tatcaatgcg ggcgcggaaa
    27301 tcttcttcaa tgaaaatatc ccattctgat tgtgatgcct gtaaatattc ccctacgcct
    27361 tctactacct gccggtcata ggctttattg gcattgaaca gtaatgtgat gcggtgacgt
    27421 ttagtaaaca tggttctttt cctgctgaat catgcaaaaa ctcaaaaccg gtaatacgta
    27481 accggctttg agaaaatttt tatcaaaatc aagaacggcg tttggttgcg gagtccatcc
    27541 atactgccag caacagaatc gcacctttaa cgatatactg ccagaaggtc ggtacatcca
    27601 tcatactcat gccgttatcc agtgaagcca tgataaatgc ccccattact gctcctgcaa
    27661 cgcttcccac accgccagcc aggctggtgc cgccaatcac gcatgctgca attgcgtcca
    27721 gttcggcgat atttcccgca gaaggtgaac cagcgccaag tcgagaacta aggattaatc
    27781 cggcgatggc taccattaat ccgttaatcg cgaacacggc aagtttggtg cgttcaacgt
    27841 taatcccgga gagacgtgct gcttccagat tgccgccgat ggcataaatg cgtcgtccaa
    27901 atgccgtccg cgttgccata aacattccgc cgagtaacag caacgtcagc agcagaacag
    27961 gagtgggaac gccacggtaa tcattcaaca gccagattgc gcctaatacg atgatagcgg
    28021 ttaaagcctg gcgaccgact actgcggtag aggccggaga ctgcaaaccc aaagcctgac
    28081 ggcgcattct tccgcgccat tgccaaccaa caaaagccat taagccaagc gcgccaatga
    28141 tgaagccagt gctggcaggt agatagcttt gcccaatttg tgacatcgcg gcgctggtgg
    28201 gggaaacagt cgtgccgttg gtgatgccaa tgagtatgcc gcgaaatgcc aacatgcccg
    28261 cgagggtgac aataaatgaa gggactttgc ggtacgcgac ccaccatccg ttccaggcac
    28321 cgagaagcag tcccagaacc aacgtcacaa tgatggtaag tggcaaaggc cagcctaacc
    28381 agacgtcaca aatcgccgcg acgccaccta atagccccat cattgagccg acggaaaggt
    28441 cgatttcagc agaaattatg acgaacacca ttcctaccgc gaggatgccg gtaatcgcgg
    28501 tctggcgtaa caggttggag acgttacggg cgcttaagta ggcaccatcg gtggtccagg
    28561 taaagaacag catgattgcg atgatagctg caatcatcac gaagacctgc aaattcagtg
    28621 atttcagccc ggaaaagcca ccggatgtcg gtacggccaa tttcacttca gacggattgc
    28681 ttttcgacat gatgttcgct cctcaatgcg gcttccatca cctgctcctg agtcaggtta
    28741 tgatttatca ggttggcttt tagtttccct tcatgcatca ccagtacccg atcgctaagg
    28801 ccgagcactt caggtaattc ggaagagatg acaataacgg caataccctg ctggacgagt
    28861 tggttaatta atttgtagat ctcgtatttc gcgccaatat cgatacccct ggtaggttca
    28921 tcaagaatga ggatgcgcgg gttaagtaac agacagcgag cgaggatcgc tttttgctga
    28981 ttgccgccgc tcaaacgtcc aatagcaagg tcgggggacg acgttttaac tttgagttgc
    29041 tgaattgatt ccagaataca tttttgctct gccgcgtcat caagctggct aatgccaccg
    29101 gtaaatttat tgagtgcggc gagggtaata tttttaccaa ccgccattac cggaacgatg
    29161 ccgtcgcgct ttctgtcttc gggtaccatc gcaatcccct gggcgatggc ttgctgacag
    29221 ttacgaatat ctacctgttt gccatcaata taaatttttc cttcccattg tccgggccac
    29281 acgccaaaca ggcactgaat ggtctcggta cgtccggcac caacgagtcc ggcaataccc
    29341 agtatttcgc cacgtttcag ggaaaacgag acatcattaa ctcgtttaat atgacgattg
    29401 accggatgcc atgccgtcag atgttcaata cgtaatattt catctccggt ggtatgtggt
    29461 tcattagggt aaagcgcggt taactctcgc ccgaccatca tggtgataat atcgtcttca
    29521 ctcattccgg cagcatcacg cgtaccaatg tgctgtccgt cgcgaataac gcaaatcgta
    29581 tcggaaatcg ctttgacttc gttgagtttg tgcgaaatat aaatacaggc gataccgtgc
    29641 tgttgtagat cgcgaataat atccagtaaa accgacgttt cctgctcagt taatgaggct
    29701 gtcggttcat cgagaattaa caagcgcacc tgtttattaa gtgccttggc aatttcaacc
    29761 agttgttgtt gcccaagccc taaatcgcca acgcgggtat caggtgaaat ggataaactg
    29821 acctgtgcga gcagcttctg acagcgtagc gtcatcaggt cataatccat aatgccattg
    29881 tgggttattt cgttacccag gaagatattt tccagcacgg tcaattcttt caccagggcc
    29941 aattcctggt gaatgatggc gatacctttg cgttcggtat cgcggatgtg actcgcctga
    30001 atctcttctc ccgcaaaaat aatttcgcct tcgtaggagc catggggata aataccacac
    30061 agcactttca tcagtgttga tttaccagac ccattttccc cacaaagtga gacgatttcg
    30121 ccagcattca accgcaagca gacgttatca atcgccttca cactgccgaa ggttttggta
    30181 atattcttca tttcaagtag ataaggcata acgactccac ctaagccaat tcattcacgc
    30241 ggcatggaga gaaatcacgc ccccgctccg cgccggggcg taacgcttac agctcgctct
    30301 ctttgtggaa tccgtcttta actaccgtgt ctttgatgtt gtttttattc acatcgatcg
    30361 gtgtcaggag gcgggagggc acatctttca ggccattatt cagtgtggta tctgcttttg
    30421 gttcctgacc attgcccaac tcaacggcaa tttctgcggc agtatttgcc aacaacgtaa
    30481 taggtttata caccgtcata gtttgcgtac cggcagcaat acgtttaata cctgcgagat
    30541 ccgcatcctg gccggaaatt gctactttcc ctgataaacc ttgcgcgctt aatgcctgaa
    30601 ttgccccacc tgcggtggca tcgtttgagg caactacagc atcaattttg ttattattgg
    30661 cggttagcgc gttttccata attttcaatg cgttttccgg taaccagcca tcaacccatt
    30721 ggtcaccaac gactttaatt tttccggaat caacgtaagg ttttaacact ttcatttgtc
    30781 cggcgcggaa cagcttggcg ttgttatcta ccggcgagcc gcccatcagg aagtaattac
    30841 cttgcggaac aatatcgacc agggcttttg cctgcagttc accgactttt tcgttatcga
    30901 aagaaatata aaaatcgata tccgcatcgt taatcatacg atcgtaagct aatactttaa
    30961 taccttcttg tttggcttct tttacaacgt tacttaatac ctgaccgtta tacggaataa
    31021 tgacaagaac atcgacaccc cggtttatca tgttttcaat ctgcgacatt tgtgtttctt
    31081 cattgccatt tgcagactgt acaaatactt tcgcgccgag agattctgcc tttttcacaa
    31141 aaatatctcg atctttttgc cagcgttcaa gacggagatc atcaatcgcc atacctattt
    31201 tgacttcttt ggcgtgtgcc gcaacgttgg taagcagaag tgaggtgcaa agggtgagta
    31261 gaatgttctt tattttcatg gtgtagggcc ttctgtagtt agaggacagc tttaataagt
    31321 aacaatcacc gcgataaacg taaccaattt ttagcaacta aacaggggaa aacaattaca
    31381 gatttttatc tttcgattac gatttttggt ttatttcttg atttatgact gagatcttac
    31441 ttttgttgcg caattgtact tattgcattt ttctcttcga ggaattaccc agtttcatca
    31501 ttccatttta ttttgcgagc gagcgcacac ttgtgaatta tctcaatagc agtgtgaaat
    31561 aacataattg agcaactgaa agggagtgcc caatattacg acatcatcca tcacccgcgg
    31621 cattacctga ttatggagtt caatatgcaa gcctattttg accagctcga tcgcgttcgt
    31681 tatgaaggct caaaatcctc aaacccgtta gcattccgtc actacaatcc cgacgaactg
    31741 gtgttgggca agcgtatgga agagcacttg cgttttgccg cctgctactg gcacacattc
    31801 tgctggaacg gggcggacat gtttggtgtg ggggcgttta atcgtccgtg gcagcagcct
    31861 ggtgaggcac tggcgttggc gaagcgtaaa gcagatgtcg catttgagtt tttccacaag
    31921 ttacatgtgc cattttattg cttccacgat gtggatgttt cccctgaggg cgcgtcgtta
    31981 aaagagtaca tcaataattt tgcgcaaatg gttgatgtcc tggcaggcaa gcaagaagag
    32041 agcggcgtga agctgctgtg gggaaccgct aactgcttta caaaccctcg ctatggcgcg
    32101 ggtgcggcga cgaacccaga tcctgaagtc ttcagttggg cggcaacgca agttgttaca
    32161 gcgatggaag caacccataa attgggcggt gaaaactatg tcctgtgggg cggtcgtgaa
    32221 ggttacgaaa cgctgttaaa taccgacttg cgtcaggagc gtgaacagct gggccgcttt
    32281 atgcagatgg tggttgagca taaacataaa atcggtttcc agggcacgtt gcttatcgaa
    32341 ccgaaaccgc aagaaccgac caaacatcaa tatgattacg atgccgcgac ggtctatggc
    32401 ttcctgaaac agtttggtct ggaaaaagag attaaactga acattgaagc taaccacgcg
    32461 acgctggcag gtcactcttt ccatcatgaa attgccaccg ccattgcgct tggcctgttc
    32521 ggttctgtcg acgccaaccg tggcgatgcg caactgggct gggacaccga ccagttcccg
    32581 aacagtgtgg aagagaatgc gctggtgatg tatgaaattc tcaaagcagg cggtttcacc
    32641 accggtggtc tgaacttcga tgccaaagta cgtcgtcaaa gtactgataa atatgatctg
    32701 ttttacggtc atatcggcgc gatggatacg atggcactgg cgctgaaaat tgcagcgcgc
    32761 atgattgaag atggcgagct ggataaacgc atcgcgcagc gttattccgg ctggaatagc
    32821 gaattgggcc agcaaatcct gaaaggccaa atgtcactgg cagatttagc caaatatgct
    32881 caggaacata atttgtctcc ggtgcatcag agtggtcgcc aggagcaact ggaaaatctg
    32941 gtaaatcatt atctgttcga caaataacgg ctaactgtgc agtccgttgg cccggttatc
    33001 ggtagcgata ccgggcattt ttttaaggaa cgatcgatat gtatatcggg atagatcttg
    33061 gcacctcggg cgtaaaagtt attttgctca acgagcaggg tgaggtggtt gcttcgcaaa
    33121 cggaaaagct gaccgtttcg cgcccgcatc cactctggtc ggaacaagac ccggaacagt
    33181 ggtggcaggc aactgatcgc gcaatgaaag ctctgggcga tcagcattct ctgcaggacg
    33241 ttaaagcatt gggtattgcc ggccagatgc atggagcaac cttactggat gctcaacaac
    33301 gggtattgcg ccctgccatt ttgtggaacg acgggcgctg tgcgcaagag tgcactttgc
    33361 tggaagcgag agttccgcaa tcacgagtga ttaccggcaa cctgatgatg cccggattta
    33421 ctgcgcctaa attgctatgg gttcagcggc atgagccgga gatattccgt caaatcgaca
    33481 aagtattatt accgaaagat tacttgcgtc tgcgtatgac gggggagttt gccagcgata
    33541 tgtctgacgc agctggcacc atgtggctgg atgtcgcaaa gcgtgactgg agtgacgtca
    33601 tgctgcaggc ttgcgactta tctcgtgacc agatgcccgc attatatgaa ggcagcgaaa
    33661 ttactggtgc tttgttacct gaagttgcga aagcgtgggg tatggcgacg gtgccagttg
    33721 tcgcaggcgg tggcgacaat gcagctggtg cagttggtgt gggaatggtt gatgctaatc
    33781 aggcaatgtt atcgctgggg acgtcggggg tctattttgc tgtcagcgaa gggttcttaa
    33841 gcaagccaga aagcgctgta cacagctttt gccatgcgct accgcagcgt tggcatttaa
    33901 tgtctgtaat gctgagtgca gcatcgtgtc tggattgggt cgcgaaatta accggcctgt
    33961 gcaatgtccc agctttaatc gctgcagctc aacaggctga tgaaagtgcc gagccagttt
    34021 ggtttctgcc ttatctttcc ggcgagcgta caccacacaa taatccccag gcgaaggggg
    34081 ttttctttgg tttgactcat caacatggcc ccaatgaact ggcgcgagca gtgctggaag
    34141 gcgtgggtta tgcgctggca gatggcatgg atgtcgtgca tgcctgcggc attaaaccgc
    34201 aaagtgttac gttgattggt ggcggggcgc gtagtgagta ctggcgtcag atgctggcgg
    34261 atatcagcgg tcagcagctc gattaccgta cgggggggga tgtggggcca gcactgggcg
    34321 cagcaaggct ggcgcagatt gcggcgaatc cagagaaatc gctcattgag ttgttgccgc
    34381 agctaccgtt agaacagtcg catctaccag atgcgcagcg ttatgccgct tatcagccac
    34441 gacgtgaaac gttccgtcgc ctctatcagc aacttctgcc attaatggcg taaacgttat
    34501 cccctgcctg accgggtggg ggataattca catctatata tctcactaat taattaatat
    34561 ttagtatgaa tttattctga aaatcatttg ttaatggcat ttttcagttt tgtctttcgt
    34621 tggttactcg taatgtatcg ctggtagata tggagatcgt tatgaaaacc tcaaaaactg
    34681 tggcaaaact attatttgtt gtcggggcgc tggtttatct ggttgggcta tggatctcat
    34741 gcccattgct aagtggaaaa ggctattttc ttggcgtgtt aatgacagca acttttggta
    34801 actatgcata tcttcgcgca gaaaaactcg ggcaactgga taattttttt acccatatct
    34861 gccagttagt tgcgttaatc actatcggtc tcttgtttat cggtgtttta aatgcaccta
    34921 tcaatgctta tgaaatggtg atctacccca tcgccttttt tgtctgcttg tttggtcaaa
    34981 tgcgtttgtt tcgctcggta tgagcaacat aaagctctta cacattcagg aatgaaagga
    35041 atactgtgat ggacaacaaa atatcaacct attcaccggc ctttagtatt gtgtcatgga
    35101 tagctctcgt tggtggtatc gttacctatc tgttagggct atggaatgca gagatgcagt
    35161 taaatgaaaa agggtattat tttgccgtac tggtgttagg actgttttct gctgcgtctt
    35221 atcaaaagac cgttcgggac aagtatgaag gcataccgac cacttccatt tattatatga
    35281 cctgcctgac tgtctttatt atctctgttg cattactgat ggtaggtctg tggaatgcga
    35341 cattattact cagtgaaaaa ggtttttatg gactggcttt cttcttaagc ttgtttggtg
    35401 cagtagcggt gcagaagaat attcgtgata ccggaataaa cccgccaaaa gaaacacagg
    35461 ttacccagga agaatacagc gaataattca cgtaagcccg gtcagtccaa tgtgaacggg
    35521 cttttactta actcactaat ctgtttctgt cgattcgttg taccagcata gaaagtaaca
    35581 aactcgctgc caacgtcgcg caaaagatcc aaataatatc cagtattggc caatttttaa
    35641 gctcaattcc ccgggtgcgc agcgcatgga taatcaaggc gtggaatccg tatataccca
    35701 atgaatggcg ggagattaag ccaagtccgc gaatggtacg cgtatccagc gtgtttttaa
    35761 ccagagtcaa tagcgcgatt gcgcagataa aaaccatcgg cccacagtaa agataccagg
    35821 tatcggcaaa atttccgcgc cactgcaatt catataatgt cccgcgagag ataataaaaa
    35881 cccccgtcgc aaacagcgcg gcgctcaccc acgacagtgc tttatgctgt gtgtccatca
    35941 tccctatagc gcggcccaac atgccataca gaatgtagta aaaagtatcg ccattgatat
    36001 ataagttaat tggcagccat tcaaaaccgt caattttctg cggcactgtg tttgggttag
    36061 cgataatgcc aatcaccacc attagcacca gcaacatttt tccgccgacg ttcttcacct
    36121 gaatcagcgg tgaaaccaga taaatcaccg caatcgcgaa gaaaaaccac aagtggtaaa
    36181 acactggctt ttgcagcagg tttttcagcg ctaactccat attgatggag gtaaacagcg
    36241 caatgtagag cagtgcgatt gcgctataaa aaatcagaca taagccgata cgcaagaaat
    36301 ggcgcggctg ggcgctgcgt tcgccaaaaa agagatagcc ggaaatcatg aaaaatagcg
    36361 gcacgctgac acgagaggca gaattcagaa cattggcgat atcccaggtg acggggctaa
    36421 cactatgagc attggtcaca taccaggtag tggtgtgaat catcaccacc attaaacacg
    36481 ctatccctcg caggttatca atccagtaaa ttttgggctg catctgtgtc tctgtatctg
    36541 gttaaaaaaa gtctgaccga taaatcattc agttggcgca ctggaataat ctgagtttta
    36601 tcactacagc ttatagaggc ttaaggaaat tcgtaagata tcagccacta taccgatata
    36661 aataataaga ctcacctgca aaccagacgg taatttaatg atgatgaacg ctttctttcc
    36721 ggcaatggcg cttatggtgc tagtgggttg ttctacaccg tcacccgtgc agaaagcaca
    36781 acgggtaaag gttgatcctc tgcgttcgtt gaatatggaa gcgttatgca aggatcaggc
    36841 ggcaaaacgt tataacaccg gcgagcaaaa aatcgacgtc accgccttcg aacagttcca
    36901 gggaagctat gaaatgcgcg gttatacctt ccgtaaagag cagtttgtct gttcttttga
    36961 cgcagatggc cattttttgc atctttccat gcgttaagcc ctgctttttc ccgtttcgta
    37021 ctgtatatct tccatccagc gggtatactg atcccttcct ttaaatccac acgtatccag
    37081 cacgaaataa tatgcaaaag tttgatacca ggaccttcca gggcttgatc ctgaccttac
    37141 aggattactg ggctcgccag ggctgcacca ttgttcaacc attggacatg gaagtcggcg
    37201 cgggaacctc tcacccaatg acctgtctgc gcgcgctggg gccagaaccg atggcggctg
    37261 cttatgttca gccttctcgt cgcccgaccg atggtcgcta cggcgaaaac cccaaccgtt
    37321 tacagcacta ctatcagttc caggtggtca ttaagccatc gccggacaat attcaggagc
    37381 tgtacctcgg ttctctgaaa gagctgggca tggacccgac tattcacgac atccgtttcg
    37441 tggaagataa ctgggaaaac ccgactctgg gtgcctgggg actgggctgg gaagtgtggc
    37501 taaacggcat ggaagtgacg cagttcactt acttccagca ggttggtggt ctggagtgta
    37561 aaccggttac cggcgagatc acctacggtc tggaacgtct ggccatgtac attcagggcg
    37621 tagacagcgt ttacgacctg gtctggagcg acggcccgct gggtaaaacc acctacggcg
    37681 acgtgttcca tcagaacgaa gtggagcagt ccacttacaa cttcgaatac gcggatgtgg
    37741 acttcctgtt cacctgcttt gagcagtacg agaaagaagc gcagcagctg ctggcgctgg
    37801 aaaatccgct gccgctgcca gcctacgagc gtattctgaa agccgcccac agcttcaacc
    37861 tgctggatgc gcgtaaagcc atctccgtca ccgagcgtca gcgctacatt ctgcgcattc
    37921 gcaccctgac caaagcagtg gcagaagcat actacgcttc ccgtgaagcc ctcggcttcc
    37981 cgatgtgcaa caaagataag taagaggcgg ctatgtctga gaaaactttt ctggtggaaa
    38041 tcggcactga agagctgcca ccaaaagcac tgcgcagcct ggctgagtcc tttgctgcga
    38101 attttactgc ggagctggat aacgctggcc tcgcacacgg caccgttcaa tggtttgctg
    38161 ctccgcgtcg tctggcgctg aaagtagcta acctggcgga agcgcaaccg gatcgtgaaa
    38221 tcgaaaaacg cggcccggcg attgcccagg cgttcgacgc tgaaggcaaa ccgagcaaag
    38281 cggcagaagg ttgggcgcgt ggttgcggta ttaccgttga ccaggctgag cgtctgacta
    38341 ccgataaagg cgaatggctg ctgtatcgcg cccatgtgaa gggcgaaagc accgaagcac
    38401 tgctgccgaa tatggttgcg acttctctgg cgaaactgcc gatcccgaaa ctgatgcgtt
    38461 ggggcgcaag cgacgtgcac ttcgtgcgtc cggtgcacac cgtgaccctg ctgctgggcg
    38521 acaaagtcat tccggcaacc attctgggca ttcagtccga tcgcgtgatt cgcggccacc
    38581 gctttatggg cgaaccggaa ttcaccatcg acaacgccga tcagtatccg gaaattctgc
    38641 gtgagcgcgg gaaagtcatc gccgattacg aagaacgtaa agcgaagatt aaagccgatg
    38701 ccgaagaagc agcgcgtaag attggcggta acgctgactt aagcgaaagc ctgctggaag
    38761 aagtggcttc gctggtggag tggccggtcg ttctgaccgc aaaattcgaa gagaaattcc
    38821 tcgcggtgcc ggctgaagcc ctggtttaca ccatgaaagg tgaccagaaa tacttcccgg
    38881 tgtatgcgaa cgatggcaaa ctgctgccga acttcatctt cgttgccaac atcgaatcga
    38941 aagatccgca gcaaattatc tctggtaacg agaaagtcgt tcgtccacgt ctggcggatg
    39001 ccgagttctt cttcaatacc gaccgtaaaa aacgtctgga agataacctg ccgcgcctgc
    39061 aaaccgtgct gttccagcaa cagctgggta cgctgcgcga caaaactgac cgcatccagg
    39121 cgctggctgg ctggattgct gaacagattg gcgctgacgt taaccacgca acccgtgcgg
    39181 gcctgctgtc taagtgtgac ctgatgacca acatggtctt cgagttcacc gacacccagg
    39241 gcgttatggg gatgcactat gcgcgtcacg atggcgaagc ggaagatgtc gcggtggcgc
    39301 tgaatgagca gtatcagccg cgctttgccg gtgatgacct gccgtctaac ccggtagcct
    39361 gtgcgctggc gattgctgac aagatggata ctctggcggg tatcttcggt atcggccagc
    39421 atccgaaagg cgacaaagac ccgtttgcgc tgcgtcgtgc cgcacttggc gtgctgcgaa
    39481 ttatcgttga gaagaacctc aaccttgatc tgcaaacgct gaccgaagaa gcagtgcgtc
    39541 tgtatggcga taagctgact aacgccaacg tggttgatga tgttatcgac tttatgctcg
    39601 gtcgcttccg cgcctggtat caggacgaag gttacaccgt tgacaccatc caggcggtac
    39661 tggcgcgtcg tccgactcgt ccggctgatt tcgatgcccg catgaaagcg gtatcgcact
    39721 tccgtaccct tgaagcagct gctgcactgg cggcggcgaa caagcgtgtc tccaacattt
    39781 tggcgaaatc tgacgaagtg ctgagcgacc gcgtgaatgc ctctaccctg aaagagccgg
    39841 aagaaattaa actggcgatg caggttgtgg tgctacgtga caagctggag ccgtactttg
    39901 cggaaggtcg ttaccaggat gcgctggtcg aactggcaga gctgcgtgag ccggttgatg
    39961 ctttcttcga taaagtgatg gtcatggttg atgacaaaga attgcgtctc aaccgtctga
    40021 ccatgctgga gaaactgcgc gaactgttcc tgcgcgttgc ggatatttcg ctgttgcagt
    40081 aataacgccg ttattaaaaa gcctgccatc tggcaggctt tttttattat cgctaaataa
    40141 tacagcaacc tttaataatc ttctgctgaa taaagattat ctcatatatt aattttatga
    40201 ggttttttta ggattatatc aaggagaaga aacaaactta ttaagctaga atagccacgg
    40261 gtgcttgaga ctgtttgtct caggtattca ccgaaaggca gacagagaaa agccccacct
    40321 gactataaat caaagtgagg ctaccctatg cctgaacacc ataaggttag cctcttactc
    40381 gttggaaatc aacacagggg gctgggaatg ccgcagaaat atagattact ttctttaata
    40441 gtgatttgtt tcacgctttt atttttcacc tggatgataa gagattcact gtgtgaattg
    40501 catattaaac aggggagtta tgagctggcg gcatttttag cctgcaattt aaaagagtaa
    40561 gagtcttcgg cgggaagtta ttcccgcctt tcttacggcg ttgcgcattc tcattgcacc
    40621 caaatttatt tttcacaaaa ataatactag attttattac gcgatcgatt atttatttcc
    40681 tgaaaaacaa ataaaaaaat ccccgccaaa tggcagggat cttagattct gtgcttttaa
    40741 gcagagatta caggctggtt acgttaccag ctgccgggcc tttagcgccg ctttcgatgg
    40801 tgaaggacac tttctgacct tcgtccagag atttgtaacc atcgttctgg atagcagaga
    40861 agtgtacgaa cacgtcttta gagccatcgt caggagtgat gaagccgaag cctttgtcag
    40921 cgttgaacca ttttacgata ccagtcattt taccggacat agtgtattac ctttaataat
    40981 taagtgtgcc tttcggcgat atggcgtgct ttacagattt tgaagcgtta aaggaatgtg
    41041 cactacgagg ggtatcaacg ataactcttg aagggacttg ccttactaca ctgctttaat
    41101 ggtctgtacg tcaaaccgtt gatgtacatt aagccacgca ttggcgggtg atgcaacaat
    41161 tatttttcat atttatgatt aatcggttgg aaaacggtcc tgtcatcagg accgtaaaca
    41221 gcaataaagt ggataaaagt ctattccatc aactgcttac ttaatgccgg gttggcttga
    41281 atcaaacgca tcaattttag ttcggcactt gaaggcttca cgcgtctgga ttcccattcc
    41341 tttaccatgg cgactgatac gcccaaaacc cgggcgaaat catcgatttt taaccctgtc
    41401 ccttttcgta actgctcaat ttcggtacag gacgttgttc tgtgcgtcag ggtaattttc
    41461 tgcgtttcat ctttaaaaac aatctgttcc aggctgctca acagctcatg cattggatct
    41521 ttatattcca ttgaaaactc ctcaaatcac actgcgggat cgtgaattgc atcgaagctc
    41581 attaagaata gtcgggaaaa gcagacacag cggggtgaag tcagggcatg ctctggctat
    41641 gattcgattc agcctgtcat ttagcgtgac ttatagccac ctaacgatct gataaatgcc
    41701 gatatatctc ttaccactcc tgttttgtaa agatttcgaa aatctaacct tctgcgaagg
    41761 cgtaaatctc tggctacaaa aaaggcaacg gcactatcat tttttaacaa tgaaacaaca
    41821 aattaacctt gtttcatttt ctccatgatt ttaccaggaa gattacgtag aaagggtatc
    41881 ctgcaagcct gtcctggact atccttgtca cgtcagacac gcgtgtgtcg ttgtgcgctt
    41941 tttttgggtg aaaggagtaa gaaaatggcg acaggaaagt cctgctctcg ctggtttgcg
    42001 cctcttgcgg cgttattaat ggtagttagc ctgagtgggt gttttgataa agaaggcgat
    42061 cagcgtaaag cgtttatcga cttcctgcag aatacagtga tgcgtagcgg tgaacgtcta
    42121 ccaaccctga ctgccgatca gaaaaaacag tttggtcctt ttgtctctga ttacgcgatt
    42181 ctgtatggtt attctcagca ggtgaatcag gcgatggatt ccggtctgcg cccggtcgta
    42241 gacagcgtta acgcaattcg cgtaccgcag gattacgtta cgcaaagcgg tccgctgcgt
    42301 gaaatgaacg gttcgctggg tgtgctggcg caacaactgc aaaatgcgaa gttgcaggcc
    42361 gatgctgcgc actctgcgct aaaacagacc gatgatttga aaccggtctt tgatcaggca
    42421 ttcaccaaag tggtaacgac gccagctgat gcattgcaac cgttgattcc ggctgcacaa
    42481 actttcacgc aacaactggt gatggttgga gactacattg ctcagcaagg tactcaggtg
    42541 agctttgtcg caaatggcat ccagttcccg acttcacagc aggcaagtga atataacaaa
    42601 ctgattgcgc cattaccggc acaacatcag gcgtttaatc aggcctggac tacagcagtt
    42661 actgcaaccc aataaagagt aaaagcccga gcgattatcg ggctttactt cacgcagtcg
    42721 cggcttagtc cgcgacgtgc ggattcacac agttcttctc aacctttcct tgtaacgcat
    42781 caatcaaatt atccacggca caggcggcca tgccataacg cgtctcatgg gtggcagatc
    42841 caatatgcgg tactgcgacg acgttggcca ttgagagcaa cggcgaatct acggacagtg
    42901 gctcttgttc gaagacatcc agcccggcgg cgtgaatttc gcctttctgc aatgcagcaa
    42961 tcagtgcatt ttcatcaacc accgggccac gtccggcatt aatgaaaatg gcggaggatt
    43021 tcattttggc gaattgttct gcgccaaaca gatgatgcgt ctcatcagtt aacggcagga
    43081 tcaggcaaac gaaatctgac tcttgtaaca gagtatccaa atcgcagtag cgggcgttga
    43141 agcgttcttc tgcttcttta tggtggcggc gcgcgttata gaggatgggc atgttgaagc
    43201 caaagtgcgc acgttgtgcc agcgccatac cgatccgtcc catcccgaca atgcccagtg
    43261 ttttatggtg aacgtcagtg ccgtaccagt ccgggcctat gctcgcggtc cattcgcctg
    43321 cttttacccg ttctgctacc tccacaaccc gacgagcggt agacaacacc agcgccatca
    43381 gcgtatcggc gacggtttct gttaatacgg ttggcgtgtg catcagcaga atttttcggg
    43441 cggtaagcgc atcgacatca aaattgtcat agccgacgga gatcgttgat gtggcacgca
    43501 gtttcggcat tttttccagc aatgcggcat caacattctc gtttgaaccc agtaaacctt
    43561 cagcttcggc aaaaattgct gcattttgtt cgacggtttg tgggctgagg tttgccacct
    43621 ggtgaacggt gaaatgctct tgcaggcgtt gcagtaaatc atcaggtaag gctttgtaga
    43681 ggataacgga cggcttcatg cttctctcca ttcactgata aggcgatcac cttagcctga
    43741 aatatgatga aggaaaactg aagaatgcca ggtgatttct gcatcacctg gcatgaaagg
    43801 gattacagcg ggcttaaggt aatttctaca cggcggtttt gcgccttacc ttctgcggtg
    43861 ctgttgctgg cgattgggtt agccgggcca aggccctgag tacggatgcg gctggcgtcc
    43921 acgccctggg tgatcaacgc gctggcaacg gaatccgcac gttgctggga gagacgcatg
    43981 ttcaggtcgt gaccacccgt gctgtcggta taaccaatca cgttaaccgc cgttttcgga
    44041 tactctttca gcaccattgc cacgccggtc agggtgttag cgcccgcagg tttcagggtc
    44101 gcgctgctgc tgtcgaaggt cacattgttc ggcatattga ggataatgtt atccccgctg
    44161 cgggttacgc taacaccagt gccgcgcatt ttgtcacgca gcttcgcttc ctgcacatcc
    44221 atgtaataac ccacgccgcc gcccagagct gcgcctgctg ctgcgccaat cagcgcgcct
    44281 ttaccgcgat ctttcttcga agaagagagc gcaccaatac ccgcgcccac gagagagccc
    44341 agacctgcgc cgatagcaga tttacctgct tcgcgttcgc cggtgtaagg gttagttgtg
    44401 cagccagata ccgccagagc gccactcact acggcggcaa taagataaac acgtttcttc
    44461 attgttaatc cttaataacc tttttattct ttgccacggg ttccgtggcg ggagattatg
    44521 ccgcgtgaac atgaagatta ttcctgggaa tactcggaaa tttgtaagta atatttaact
    44581 gctcaataca tctaaccttt caggagtttt cggtttggcc aactcatcct cacgatattc
    44641 cgttctgact gccgcccatt gggggcccat gctggttgaa accgacggcg aaaccgtgtt
    44701 tagctcgcat ggcgcgttag ccacaggaat ggaaaactcc ttgcagagcg cggttcgcga
    44761 ccaggttcac agcaatacac gggtacgatt tccaatggtg cgcaaaggct ttcttgcgtc
    44821 accggaaaat ccgcaaggca ttcgtgggca ggatgaattt gttcgcgtga gttgggatga
    44881 ggcgctggat cttattcacc aacaacataa acgcattcgt gaggcttatg gtccggcatc
    44941 gatttttgct ggttcctacg gctggcgttc aaacggcgtg ctgcataagg cctcgacatt
    45001 attacaacgc tatatggcgc tggcaggcgg ttataccggg catctggggg attattcgac
    45061 cggcgcggca caggcgatca tgccgtatgt cgtgggtggt agcgaagttt atcaacagca
    45121 aaccagttgg ccgctggtgc tggaacatag cgatgtcgtg gtgttgtgga gtgctaaccc
    45181 actcaatacg ctgaaaattg cgtggaatgc atctgatgag caggggcttt cttacttttc
    45241 cgcactgcgt gacagcggga aaaagctgat ctgtattgat ccaatgcgat cggaaaccgt
    45301 cgatttcttt ggcgataaaa tggagtgggt ggcaccgcac atgggcaccg atgttgcgct
    45361 gatgctgggg atcgcccata cgctggtgga aaatggttgg cacgacgaag cgtttctgac
    45421 gcgttgcacc acaggttatg ccgtcttcgc ctcttatttg ctgggcgaga gtgacggaat
    45481 agcgaaaaac gccgaatggg cggcagagat ttgtggggtt aacgcagcga aaatccgcga
    45541 gctggcggct cttttccacc aaaacacgac catgctgatg gctggctggg gaatgcagcg
    45601 ccaacagttt ggtgagcaaa aacactggat gatcgtcacg ctggcggcaa tgttggggca
    45661 aatcggcaca cccggcggcg gttttggtct ttcttatcat tttgccaatg gtggtaaccc
    45721 cacgcggcgt tctgcggtgc tctcttccat gcagggcagc ttgccgggtg gctgcgatgc
    45781 ggtggataaa atccctgttg cccgcattgt tgaagcactg gaaaaccctg gtggcgcata
    45841 tcaacacaac ggtatgaacc gacatttccc ggatattcgt tttatctggt gggcgggcgg
    45901 tgccaacttt actcatcatc aggataccaa tcgtctgatc cgtgcctggc aaaaaccgga
    45961 gctggtggtg atctctgaat gcttctggac ggcggcggcg aaacacgcgg atatcgttct
    46021 gcctgcgact acctcttttg agcgtaatga tctcaccatg accggtgatt acagtaatca
    46081 gcatctggtg ccgatgaagc aagtggtgcc gccacgctat gaagcgcgta atgattttga
    46141 tgtttttgcc gagttgagtg aacgttggga gaagggcggc tatgcgcggt ttacggaagg
    46201 aaaaagtcag ctgcaatggc tggaaacgtt ttataacgtt gcccggcagc gcggggcaag
    46261 ccagcaggtt gaattgccgc catttgctga gttctggcaa gccaaccagt taattgagat
    46321 gccggaaaac ccggacagcg agcggtttat tcgcttcgct gatttttgcc gcgatccgct
    46381 ggcgcatccg ttaaaaaccg ccagcggcaa gattgaaatc ttctcacagc gtattgccga
    46441 ttacggttac ccggattgcc ctgggcatcc aatgtggctg gagccggacg aatggcaggg
    46501 aaatgccgaa ccagaacagt tgcaggtact ttctgcccat ccggcgcacc gcctgcacag
    46561 ccagctgaat tacagttctc tgcgcgaatt gtacgcggta gcaaaccgtg agcctgtcac
    46621 cattcatcct gacgatgctc aggcgcgcgg cataaccgaa ggggatatgg tgcgggtgtg
    46681 gaactcccgt gggcagatcc ttgccggagc ggtcattagc gagggaatta aacctggcgt
    46741 gatttgcatt cacgaagggg catggccgga tctggattta accgctgacg gtatttgtaa
    46801 aaacggcgca gtgaacgtgc tgaccaaaga tctccccagc tcgcggctgg ggaatggctg
    46861 tgcgggtaat acggcgctgg catggctgga aaaatacaac ggtccggaac tgacacttac
    46921 agcgtttgaa ccaccggcca gctcataatc caggtgggta gttgggtttc atcctgccat
    46981 gcgcaatcga caatgtgaaa accctgcgca cggtaaaaat ctatcgccgg ttgatttttt
    47041 tgataaacct ccagcatcag atggggatag cgctgctgca catactgcat cagcgcctta
    47101 ccaataccgc gtctgacggc cttcggtgcg acaaacattg ctgccagaaa tcggccttcc
    47161 ataatgctga caaaaccgag aagcttaccg tcctcttccc agacccagtt ttgcgcgttg
    47221 gcaagatagg catcccgcac cagcggaatg cagtcacgcc agtaattcgc ttttataaag
    47281 ggatgccccc aggttgtact ttccagccac agttcgagga tcgcggggag ttctgaacgt
    47341 tgcgcttccc gaatcatggt ttatttcccg gatagcaaca gcagccaacc acatgatcat
    47401 tcaccagccc acatgcctgc ataaaggagt aacagattgt ggtgccgaca aacttaaaac
    47461 cacgtttttt cagtgcctta gatagggcgt cggaggcgga cgtagatgtg ggaatttcgc
    47521 tcaacgttgt ggcttgtgtc acctgtggct gatgatttac aaacgaccag acaaagtcgg
    47581 caaacggttc gccgttctgt tccatttgca ggtacgcccg cgcattacca ataattgcct
    47641 gaattttccc tcgatggcgg ataatcccgg cgtcctgtac cagtctttcg acatcctctt
    47701 cctgcattgc tgcgaccttc accggatcga actgatgaaa gcaggcgcga tagttttcgc
    47761 gttttttgag gacggtgatc cacgataacc cagcctgctg cccttcaagg cagatcattt
    47821 cgaacagttt tttactgtca gtttcaggca cgccccattc attatcatgg taggcaatat
    47881 aaagcgggtc ctgactcacc cagccgcaac gttccatact ttccctcgct atgtacccga
    47941 tcgtaaaaat ttcagccgct tttcttgacg catcggtgaa aaagtcaata tttaatacag
    48001 ggctactatg cccgatatcc ttcatgcaat gacaataata ttgccgaatt cggctcttcc
    48061 ctggagtcgt gttaatgatc ataaaaaaaa gcggtggtcg ctggcagcta agcctgctgg
    48121 cgagcgtggt aatcagtgcc ttttttctca acacagctta cgcctggcaa caagaatata
    48181 tcgttgatac gcaacccgga cattccacag agcgttacac ctgggatagt gatcatcaac
    48241 ctgattacaa cgatattttg tcgcaacgta ttcaaagtag ccaaagggcg ctgggactgg
    48301 aagtcaatct ggcggaagaa actcctgtgg atgtgaccag cagtatgagt atgggctgga
    48361 attttccttt atatgaacag gttacaaccg gcccggtcgc ggcattacat tacgatggca
    48421 caaccacctc gatgtataac gagtttggcg acagtactac cacgctgacc gatccgttat
    48481 ggcatgccag cgtgagtagc ttaggctggc gtgttgactc ccggcttggc gatctccgac
    48541 cctgggcgca aatcagctat aaccagcaat ttggcgagaa tatctggaag gcgcaatcag
    48601 gcctgagccg gatgacggcg acaaaccaga acggcaactg gctggatgtc accgtaggcg
    48661 ctgatatgtt gctcaatcaa aatattgccg cctatgccgc gctaactcag gcagaaaata
    48721 ccactaataa tagcgactat ctgtatacga tgggggttag cgccagattt taacgtaaca
    48781 gtcacaattg aaaccattga ataacaacag ttgtggcgat agtgggtgct aacttaccaa
    48841 ataataaatt tggtgaataa ttgtcgcgtc attcattcct gaactaaggc atttcattcc
    48901 gttctgatgg catttcatgc cgtttttccc caggcataaa atgcacttcg ttatggttgt
    48961 cggcagagat ttttcctttt tattactgca ggaatactgc catgacacct tcaaattatc
    49021 agcgtacccg ctggctgaca ctcatcggta ctatcattac ccagtttgca ctggggtcgg
    49081 tttatacctg gagcctgttt aatggcgcgc tttctgccaa gctggatgcg ccggtaagcc
    49141 aggtcgcttt ctctttcggc ttgttaagtc tggggctggc aatttcgtct tctgttgcgg
    49201 gcaaattgca ggaacgtttt ggcgttaaac gcgtcaccat ggcttccggc attttgctgg
    49261 gattaggctt cttcctgacc gcgcattcca acaacctgat gatgctgtgg ttaagcgccg
    49321 gtgtgctggt cggtctagcg gatggcgcgg gttacctgct gacgctctct aactgcgtga
    49381 agtggttccc ggagcgtaaa ggtctgatat ccgcgttcgc tatcggttct tatggtctgg
    49441 gtagcctggg tttcaaattt atcgacacgc agctgctgga aacggtgggt ctggaaaaaa
    49501 cctttgtgat ttggggagcg attgcgctgg tgatgattgt tttcggcgca acgttaatga
    49561 aagacgcacc aaaacaggaa gtgaaaacca gcaatggcgt agtggagaaa gattacacgc
    49621 tggcagagtc gatgcgtaaa ccgcagtact ggatgttagc ggtaatgttc ctgactgcct
    49681 gcatgagcgg cctgtacgtg attggggtag cgaaagatat cgcccaaagt ctggcacacc
    49741 ttgatgtggt ttccgcagcc aatgcagtaa cggttatttc catcgctaac ctttcaggtc
    49801 gtctggtgct gggcattctg tctgacaaaa ttgcccgtat ccgtgttatc accattggtc
    49861 aggtgatttc gctggtgggt atggcggccc tgctgtttgc accattaaat gcagtgacgt
    49921 tctttgcagc gattgcctgc gtggcattta actttggcgg cactattacc gtctttccat
    49981 cactggtcag tgagttcttt ggcctcaata acctggcgaa aaactacggt gtgatttacc
    50041 tcggtttcgg tatcggtagc atttgtggtt cgattatcgc ctcactgttt ggcggcttct
    50101 atgtgacctt ctacgtgatt ttcgccctgc tgattctgtc attggcgctt tctacgacaa
    50161 ttcgtcagcc agagcagaaa gtattgcgtg aggcgcatat ttagaaatat gttgctactg
    50221 aaataaatgc gaggagggag acttcaaagt ctcccttttt ttatggacgc atattaaaag
    50281 aacaataata ttta
//
LOCUS       DAZUDJ010000032        49289 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.032, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000032 DAZUDJ010000000
VERSION     DAZUDJ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49289
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.032"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(25..984)
                     /locus_tag="ACHY1N_002492"
     CDS             complement(25..984)
                     /locus_tag="ACHY1N_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HFS4044790.1"
                     /translation="MKICIDDGSTNIKLAWTENGERRNAISPNSFKSEWSAPFGGTQP
                     ANYMLDGVRYGFDPVSDRFVQTTDTQYQYSDVNVIAIHHALVKSGITPQEVDVVVTLP
                     LSEYFDTNAQPDMANINRKKANVMRPVAYQNGKAFTIRNVRVMPESIPAGFKALADMS
                     PFESLLIVDLGGTTLDVAKVQGQLAGISQVFCDPHVGVSLMADAVLSVMATNGMRTSH
                     HIANTIIEHRHDEAWLRQHIHNDAHYASLMAVIREKEETLKQRVIRALAGFSGYGRVM
                     VVGGGAEIVAPAIREACGVNATFIADGVPQFALVNGLYAMDKE"
     gene            complement(1061..3883)
                     /locus_tag="ACHY1N_002493"
     CDS             complement(1061..3883)
                     /locus_tag="ACHY1N_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HFS4044791.1"
                     /translation="MATEYIRNWQQPRHAVGREGTGEPVRPSLLSSWLDAYRAENERR
                     QEMADAAFSAAPLGNLINKSLDAQEKQDKAITLAREARKQARGAVDEAIAALRLLPSY
                     LRDPLIRHLSFLRKKQESDRQKGKKSWQAERYARGTLRKIFERLERTDRRWLTPGYRS
                     LAGRERLDDLLYLPQLNKHQIQTLAVMTAAMFSSTFEKLCDDFGATDGELTMDITLKA
                     YQMLARMALHLHTVPPHYDALTTDKDRKNEPDTELLPGAILRLTCADWWKRKLWLLRC
                     EWREEQLRAACLVSRKTSPYLSQDALSEFRAQREKTRDFLKSFMLENEDGFTIDLETV
                     YYAGVSNPVHRKAEMMATMKGLELLAEARDDRAVFLTVTCPSKYHATTENGHPNPKWN
                     GATMRDSSDYLVNTFFKAVRKKLNRDGLRWYGIRTVEPHHDGTVHWHMMVFAHPEEID
                     SIVDITRDIAIREDRHELGNDITPRFKAEYVDGSKGTPTSYIATYIGKNLDSRAVDGI
                     DPKTGKPRVDHETGKSMAESVERAIGWARLHRVRQFQFFGIPSRQVWRELRRLASQMA
                     RNPEGPQRLKDDAMDAVLAAADAGCFATYIEKQGGVLVPRKDYLIRTAYDLADELNDY
                     GEQSVQIYGIWSPLIGESSRVCTHPDNWKLVRRKPEAEDSTRENGFDLQGGPAAPWTR
                     GNNCPRVQETDNNGTEQPEEQPAPWSQLPDGVEVNEWMRSLKRHERRALMRSLRDKQA
                     KNSRDEMQSWTQSRKQQRPLPDNHELLAKEWRESAESLGLHIGEQQMQHLLRGGSLYV
                     DGSIIAPQGFEIVRKPDTRPDSRITQLWQRLSRNHGVSSTEIRHNPVASYLEQLGTSD
                     PEAAARLASTLQQDQNTMKTPVTVLSDMLRAIRDAEHAQRISETTERARRKADLLRGG
                     LTSGNKKQTETGFTNPVNEQKTRRDI"
     gene            complement(3889..4254)
                     /locus_tag="ACHY1N_002494"
     CDS             complement(3889..4254)
                     /locus_tag="ACHY1N_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044792.1"
                     /translation="MILAEDFFDYLLKTERDFGIRVLDRYAMYLKSLPEQQLPDGQIV
                     IDGRYMVGSCQDDYTLSRIESGTPSVLGIYQRTSSLIADVIADSIRITHRYASTESTM
                     QEIQRLATVCHNALSGKAE"
     gene            complement(4251..4364)
                     /locus_tag="ACHY1N_002495"
                     /pseudo
     CDS             complement(4251..4364)
                     /locus_tag="ACHY1N_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310657.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4396..4662)
                     /locus_tag="ACHY1N_002496"
     CDS             complement(4396..4662)
                     /locus_tag="ACHY1N_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4044793.1"
                     /translation="MTILDYIATHPGCSGGEIAAALNTPTTAINAELRRLWRGGLVIR
                     TNRSTGGRARKTGGQASYHVNPMPFGCSNPLTHMFNQLLREIRA"
     gene            complement(4659..4862)
                     /locus_tag="ACHY1N_002497"
     CDS             complement(4659..4862)
                     /locus_tag="ACHY1N_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044794.1"
                     /translation="MAIKHFPVVRFTSRGREYEVDERLITTIDKHRSEKDAHHIYLTD
                     GTYFCATNVARVNLIRQVQEPRR"
     gene            complement(4949..5062)
                     /locus_tag="ACHY1N_002498"
     CDS             complement(4949..5062)
                     /locus_tag="ACHY1N_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044795.1"
                     /translation="MSIFISWLVLIISVACAIGIMRIINSVKKIERFFTEE"
     gene            complement(5059..5301)
                     /locus_tag="ACHY1N_002499"
     CDS             complement(5059..5301)
                     /locus_tag="ACHY1N_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4754 family protein"
                     /protein_id="HFS4044796.1"
                     /translation="MDKEYKTLVNKALERFHFRLSASGTHAELAARESLTRAIKSIYD
                     TAFYIDDPDALDELSVLVCAAENGDHIEPYKLGNIA"
     gene            complement(5313..5591)
                     /locus_tag="ACHY1N_002500"
     CDS             complement(5313..5591)
                     /locus_tag="ACHY1N_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044797.1"
                     /translation="MTKDHAQGVFIRFIDFRGELLLRASAIDGVVPVDKSTATYIYLN
                     GTRLTVEIPYQHVCEIISEAEKARQVNGNKPYLEIICMDSEAEIQKAD"
     gene            complement(5602..5940)
                     /locus_tag="ACHY1N_002501"
     CDS             complement(5602..5940)
                     /locus_tag="ACHY1N_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001698482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4761 family protein"
                     /protein_id="HFS4044798.1"
                     /translation="MLKQRRNFFTGTERHANRFATSASRSNSRYSLSETHATPDGHPV
                     KQIGEHTWLIEKAGIVVHRCQRNPFTGNRIFALSNGDNQFGQDFTLYEALRTVDRLLR
                     GQNFIKQADL"
     gene            complement(5955..6233)
                     /locus_tag="ACHY1N_002502"
     CDS             complement(5955..6233)
                     /locus_tag="ACHY1N_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFS4044799.1"
                     /translation="MTKLLNTYEQADFERLAAFYPYRDEHGLPVLEESLKDYAKRTNQ
                     TVNAVKRQADRAALPINQEEKNSKRTVNLFAIFLKTIRNAEKYVQMTK"
     gene            6325..6636
                     /locus_tag="ACHY1N_002503"
     CDS             6325..6636
                     /locus_tag="ACHY1N_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4044800.1"
                     /translation="MSSGYEKKLKEIRKSEGLTQAEFADVTGINLGTIKNYESGKREV
                     GLSVVDRVINSKDFEKYTIWLMTGKTNEAAGQISPSLSPDGPENTSSSQKSRKTGTQP
                     G"
     gene            6725..7663
                     /locus_tag="ACHY1N_002504"
     CDS             6725..7663
                     /locus_tag="ACHY1N_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4044801.1"
                     /translation="MRPEGRKGKRIRKKFKTKSDAVLYERWVLAQQHNNEWKGNSIDR
                     RPLSVLIELWWKYHGQLMKSGHNTRLKLLRLSEVMDDPCVHKLNTTMLTELRVSRIEQ
                     GIQPSTINREIGALSAMFTALISSGHFLNDNPVQGLKGMKVNEREMGYLSKSECVQLL
                     DALAENPDERLAVEILLSTGARWGEVAALEQRRVLHCRITFSKTKNSKNRTVPISESL
                     FEKIKKRGGKLVFPTLDYPLVRDVIKTVAPDVPDGQAVHALRHTFASHFMMNGGNILT
                     LQKILGHAKIQTTMIYAHLAPDYLQDAVRFNPLGGM"
     gene            7666..8166
                     /locus_tag="ACHY1N_002505"
     CDS             7666..8166
                     /locus_tag="ACHY1N_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044802.1"
                     /translation="MEIKKPTKKELYDYLLSKYIEDKCKEEADEINKKSMSRVKKHKE
                     RLMEITPEIFFRFLSEKGVSSVCPSCGSSRLSVPESMDLCWDKNKKPENFNNLPLEEQ
                     SELIKENIKHYVSYTFLGDVKSIPDMRKTYYTLHCLNCGYLSLYRTSAVLKWLEKDKA
                     QDGDNG"
     gene            8267..8716
                     /locus_tag="ACHY1N_002506"
     CDS             8267..8716
                     /locus_tag="ACHY1N_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001434769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1640 domain-containing protein"
                     /protein_id="HFS4044803.1"
                     /translation="MSDKLERRIERLEGDLSLTRNDLATLAERTTNLSTKADVGEVKG
                     ELKADIAHLKGDLECGIANLKGELKSDTANLKEQLKSDINSLKGEIAEAMDKRFDKIM
                     DEMNRRFDKVDDNTKWRLSGIIIPVCIAIFTSLFTAAATYFIAKFVG"
     gene            8909..9889
                     /gene="btuC"
                     /locus_tag="ACHY1N_002507"
     CDS             8909..9889
                     /gene="btuC"
                     /locus_tag="ACHY1N_002507"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HFS4044804.1"
                     /translation="MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWF
                     TPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGE
                     ISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKARR"
     gene            9952..10503
                     /gene="btuE"
                     /locus_tag="ACHY1N_002508"
     CDS             9952..10503
                     /gene="btuE"
                     /locus_tag="ACHY1N_002508"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional thioredoxin/glutathione peroxidase"
                     /protein_id="HFS4044805.1"
                     /translation="MQDSILTTVVKDIDGEVTTLEKYAGNVLLIVNVASKCGLTPQYE
                     QLENIQKAWADRGFVVLGFPCNQFLEQEPGSDEEIKTYCTTTWGVTFPMFSKIEVNGE
                     GRHPLYQKLIAAAPTAVAPEESGFYARMVSKGRAPLYPDDILWNFEKFLVGRDGLVIQ
                     RFSPDMTPEDPIVMESIKLALAK"
     gene            10503..11252
                     /gene="btuD"
                     /locus_tag="ACHY1N_002509"
     CDS             10503..11252
                     /gene="btuD"
                     /locus_tag="ACHY1N_002509"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015889 - cobalamin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HFS4044806.1"
                     /translation="MSIVMQLQDVAETTRLGPLSGEVRAGEILHLVGPNGAGKSTLLA
                     RMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKT
                     RTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEP
                     MNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRRE
                     EVLTPPNLAQAYGMNFRRLDIEGHRMLISTI"
     gene            11330..11794
                     /gene="nlpC"
                     /locus_tag="ACHY1N_002510"
     CDS             11330..11794
                     /gene="nlpC"
                     /locus_tag="ACHY1N_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFS4044807.1"
                     /translation="MRFCLILITALFLAGCSHHKAPPPNARLSDSITVIAGLNDQLQS
                     WHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPRETKEQASIGTQIDKDELLPGDL
                     VFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI"
     gene            12041..12754
                     /gene="ydiV"
                     /locus_tag="ACHY1N_002511"
     CDS             12041..12754
                     /gene="ydiV"
                     /locus_tag="ACHY1N_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor"
                     /protein_id="HFS4044808.1"
                     /translation="MKIFLENLYHSDCYFLPIRDNQQLLVGVELITHFSSEDGTVRIP
                     TSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKLFAWLNLTPQVATLLLERDNYAG
                     ELLKYPFIELLINENYPHLNEGKDNRGLLSLSQVYPLVLGNLGAGNSTMKAVFDGLFT
                     RVMLDKSFIQQQITHRSFEPFIRAIQSQISPCCNCIIAGGIDTAEILAQITPFDFHAL
                     QGCLWPAVPINQITTLVQR"
     gene            12817..14253
                     /gene="selO"
                     /locus_tag="ACHY1N_002512"
     CDS             12817..14253
                     /gene="selO"
                     /locus_tag="ACHY1N_002512"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase SelO"
                     /protein_id="HFS4044809.1"
                     /translation="MTLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIP
                     SSLFKNAAGVWGGETLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTM
                     DWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRE
                     TVEPGAMLIRVAPSHLRFGHFEHFYYRREPEKVRQLADFAIRHYWSHLEDDEDKYRLW
                     FNDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSD
                     HQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGQRMRQKLG
                     FMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDW
                     FARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEAL
                     RNPFSDRADDYVSRPPDWGKRLEVSCSS"
     gene            complement(14257..14448)
                     /gene="hemP"
                     /locus_tag="ACHY1N_002513"
     CDS             complement(14257..14448)
                     /gene="hemP"
                     /locus_tag="ACHY1N_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HFS4044810.1"
                     /translation="MRYTDSRKLTPETDANHKTASPQPIRRISSQTLLGPDGKLIIDH
                     DGQEYLLRKTQAGKLLLTK"
     gene            complement(14580..15626)
                     /gene="aroH"
                     /locus_tag="ACHY1N_002514"
     CDS             complement(14580..15626)
                     /gene="aroH"
                     /locus_tag="ACHY1N_002514"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HFS4044811.1"
                     /translation="MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEK
                     ILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTE
                     RLVEKLASAVDTRF"
     gene            complement(15783..16616)
                     /gene="ppsR"
                     /locus_tag="ACHY1N_002515"
     CDS             complement(15783..16616)
                     /gene="ppsR"
                     /locus_tag="ACHY1N_002515"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HFS4044812.1"
                     /translation="MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVE
                     NESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQ
                     EMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
                     CGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIR
                     EERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRM
                     H"
     gene            16949..19327
                     /gene="ppsA"
                     /locus_tag="ACHY1N_002516"
     CDS             16949..19327
                     /gene="ppsA"
                     /locus_tag="ACHY1N_002516"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008986 - pyruvate, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HFS4044813.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQP
                     ELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVL
                     VTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGEKV
                     TVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIATL
                     GAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(19384..21030)
                     /gene="fadK"
                     /locus_tag="ACHY1N_002517"
     CDS             complement(19384..21030)
                     /gene="fadK"
                     /locus_tag="ACHY1N_002517"
                     /EC_number="6.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="medium-chain fatty-acid--CoA ligase"
                     /protein_id="HFS4044814.1"
                     /translation="MKVTLTFNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVV
                     DNHGASYTYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKIGAVS
                     VPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKL
                     APATSSLSLSQIIADNTSLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILASER
                     AYCVRLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQ
                     RCTCMLGATPFVYDLLNVLEKQPADLSALRFFLCGGTTIPKKVARECQQLGIKLLSVY
                     GSTESSPHAVVNLDDPLSRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNV
                     FMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVRGGENISSREVE
                     DILLQHPKIHDACVVAMPDERLGERSCAYVVLKAPHHSLSLEEVVAFFSRKRVAKYKY
                     PEHIVVIEKLPRTASGKIQKFLLRKDIMRRLTQDVCEEIE"
     gene            complement(21087..21380)
                     /gene="ydiT"
                     /locus_tag="ACHY1N_002518"
     CDS             complement(21087..21380)
                     /gene="ydiT"
                     /locus_tag="ACHY1N_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HFS4044815.1"
                     /translation="MSQNATVNVDIKLGVNKFHVDEGHPHIILAANPDINEFRKLMKA
                     CPAGLYKQDDAGNIHFDSAGCLECGTCRVLCGNTILEQWQYPAGTFGIDFRYG"
     gene            complement(21377..22666)
                     /gene="ydiS"
                     /locus_tag="ACHY1N_002519"
     CDS             complement(21377..22666)
                     /gene="ydiS"
                     /locus_tag="ACHY1N_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4044816.1"
                     /translation="MSEDKFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKN
                     MTGGRLYAHTLEAIIPGFAVSAPVERKVTREKISFLTEESAVTLDFHREQPDVPQHAS
                     YTVLRNRLDPWLMEQAEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILAD
                     GVNSMLGRSLGMVPASDPHHYAVGVKEVIGLTPEQINDRFNITGEEGAAWLFAGSPSD
                     GLMGGGFLYTNKDSISLGLVCGLGDIAHAQKSVPQMLEDFKQHPAIRPLISGGKLLEY
                     SGHMVPEGGLAMVPQMVNDGVMIVGDAAGFCLNLGFTVRGMDLAIASAQAAATTVIAA
                     KEREDFSASSLAQYKRELEQSCVMRDMQHFRKIPALMENPRLFSQYPRMVADIMNEMF
                     TIDGKPNQPVRKMIMGHAKKIGLINLLKDGIKGATAL"
     gene            complement(22722..23660)
                     /gene="ydiR"
                     /locus_tag="ACHY1N_002520"
     CDS             complement(22722..23660)
                     /gene="ydiR"
                     /locus_tag="ACHY1N_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HFS4044817.1"
                     /translation="MSQLNSVWVFSDNPERYAELFGGAQQWGQQVYAIVQNTDQAQAV
                     MPYGPKCIYVLEQNDALQRTENYAESIAALLKDKHPAMLLLAATKRGKALAARLSVQL
                     NAALVNDATAVDIIDGHICAEHRMYGGLAFAQEKINSPLAIITLAPGVQEPCTSDTSH
                     QCPTETVPYVAPRHEILCRERRAKAASSVDLSKAKRVVGVGRGLAAQDDLKMVHELAA
                     VLNAEVGCSRPIAEGENWMERERYIGVSGVLLKSDLYLTLGISGQIQHMVGGNGAKVI
                     VAINKDKNAPIFNYADYGLVGDIYKVVPALISQLSR"
     gene            complement(23680..24444)
                     /gene="ydiQ"
                     /locus_tag="ACHY1N_002521"
     CDS             complement(23680..24444)
                     /gene="ydiQ"
                     /locus_tag="ACHY1N_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein"
                     /protein_id="HFS4044818.1"
                     /translation="MKIITCFKLVPEEQDIVVTPEYTLNFDNADAKISQFDLNAIEAA
                     SQLATDDDEIAALTVGGSLLQNSKVRKDVLSRGPHSLYLVQDAQLEHALPLDTAKALA
                     AAVEKIGFDLLIFGEGSGDLYAQQAGLLVGEILQLPVINAVSAIQRQGNTLVIERTLE
                     DDVEVIELSVPAVLCVTSDINVPRIPSMKAILGAGKKPVNQWQASGIDWSQSAPLAEL
                     VGIRVPPQTERKHIIIDNDSPEAIAELAEHLKKALN"
     gene            24760..25671
                     /gene="ydiP"
                     /locus_tag="ACHY1N_002522"
                     /pseudo
     CDS             24760..25671
                     /gene="ydiP"
                     /locus_tag="ACHY1N_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310430.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(25714..26865)
                     /gene="ydiO"
                     /locus_tag="ACHY1N_002523"
     CDS             complement(25714..26865)
                     /gene="ydiO"
                     /locus_tag="ACHY1N_002523"
                     /EC_number="1.3.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HFS4044819.1"
                     /translation="MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMR
                     ALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSA
                     EQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
                     EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEV
                     EESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAECAFEDAARYANQRIAFGKPIGH
                     NQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKLYCARTAMEVIDDAI
                     QIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK"
     gene            complement(26879..28474)
                     /gene="ydiF"
                     /locus_tag="ACHY1N_002524"
     CDS             complement(26879..28474)
                     /gene="ydiF"
                     /locus_tag="ACHY1N_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HFS4044820.1"
                     /translation="MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEAT
                     TLITALADKYKQTQTPRNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRI
                     SELAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKE
                     DLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNN
                     GGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVVVDPDQSQLYGGAPVNRFISGDFTLD
                     DSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVET
                     GPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKF
                     NGKIMGTGGFIDISATSKKIIFCGTLTAGSLKTEIADGKLHIVQEGRVNKFIRELPEI
                     TFSGKIALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPE
                     LKLMDERLFIDAAMGFVLPEAAH"
     gene            complement(28618..29376)
                     /gene="aroD"
                     /locus_tag="ACHY1N_002525"
     CDS             complement(28618..29376)
                     /gene="aroD"
                     /locus_tag="ACHY1N_002525"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFS4044821.1"
                     /translation="MKTVTVKDLVIGTGAPKIIVSLMAKDIARVKSEALAYREADFDI
                     LEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNR
                     AAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRK
                     MQSFDADIPKIALMPQSTSDVLTLLTATLEMQEQYADRPIITMSMAKTGVISRLAGEV
                     FGSAATFGAVKKASAPGQISVNDLRTVLTILHQA"
     gene            complement(29407..30273)
                     /gene="ydiB"
                     /locus_tag="ACHY1N_002526"
     CDS             complement(29407..30273)
                     /gene="ydiB"
                     /locus_tag="ACHY1N_002526"
                     /EC_number="1.1.1.282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinate/shikimate dehydrogenase"
                     /protein_id="HFS4044822.1"
                     /translation="MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEV
                     DNDSFPGAIEGLKALKMRGTGISMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLR
                     GYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEF
                     FDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVN
                     DISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFP
                     LEYVKQVMGFGA"
     gene            complement(30285..31550)
                     /gene="ydiN"
                     /locus_tag="ACHY1N_002527"
     CDS             complement(30285..31550)
                     /gene="ydiN"
                     /locus_tag="ACHY1N_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4044823.1"
                     /translation="MSQNKAFSTPFILAVLCIYFSYFLHGISVITLAQNMSSLAEKFS
                     TDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAVILMAVIMYLLFFFGIPACPNLT
                     LAYGLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPMLVSYML
                     LNNIWYGYGLIIPGILFVLITLMLLKSKFPSQLVDASVANELPQMNSKPLVWLEGVSS
                     VLFGVAAFSTFYVIVVWMPKYAMAFAGMSEAEALKTISYYSMGSLVCVFIFAALLKKM
                     VRPIWANVFNSALATITAAIIYLYPSPLVCNAGAFVIGFSAAGGILQLGVSVMSEFFP
                     KSKAKVTSIYMMMGGLANFVIPLITGYLSNIGLQYIIVLDFTFALLALITAIIVFIRY
                     YRVFIIPENDVRFGERKFSTRLNTIKHRG"
     gene            complement(31777..32991)
                     /gene="ydiM"
                     /locus_tag="ACHY1N_002528"
     CDS             complement(31777..32991)
                     /gene="ydiM"
                     /locus_tag="ACHY1N_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4044824.1"
                     /translation="MKNPYYPTALGLYFNYLVHGMGVILMSLNMASLETLWQTNAAGV
                     SIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILHTNNIIIAYVFG
                     FLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWF
                     GWSFMIAAGIMFINALFLYRCTFPPHPGRRLPVIKKTTSSTEHRCSIIDLASYTLYGY
                     ISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTT
                     LLMLYTFFSFIALFTVCLHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERFPYAKGK
                     ATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTAIAAIGFLLALFIGLRSRKKTR
                     HHSLKENVAPGG"
     gene            complement(33091..33447)
                     /gene="ydiL"
                     /locus_tag="ACHY1N_002529"
     CDS             complement(33091..33447)
                     /gene="ydiL"
                     /locus_tag="ACHY1N_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707588.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiL family protein"
                     /protein_id="HFS4044825.1"
                     /translation="MNAYELQALRHIFAMTIDECATWIAQTGDSESWRQWENGKCAIP
                     DRVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRFFPDLTAFQQVYPDGNFIDWKIY
                     QSVAAELYAHDLERLC"
     gene            complement(33583..33690)
                     /gene="rprA"
                     /locus_tag="ACHY1N_002530"
     ncRNA           complement(33583..33690)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="ACHY1N_002530"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(33876..34988)
                     /gene="ydiK"
                     /locus_tag="ACHY1N_002531"
     CDS             complement(33876..34988)
                     /gene="ydiK"
                     /locus_tag="ACHY1N_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HFS4044826.1"
                     /translation="MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTV
                     VIATWPVLLRLQKIMFGRRSLAVLVMTLLLVMVFIIPIALLVNSIVDGSGPLIKAISS
                     GDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHI
                     GRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGIGLAVSGVPYATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLIAFGMIGLFIGPVLL
                     AVSWRLFAAWVEEVPPPTDQPEEILEELGEIEKPNK"
     gene            35377..38433
                     /gene="ydiJ"
                     /locus_tag="ACHY1N_002532"
     CDS             35377..38433
                     /gene="ydiJ"
                     /locus_tag="ACHY1N_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding and (Fe-S)-binding domain-containing
                     protein"
                     /protein_id="HFS4044827.1"
                     /translation="MIPQISQAPGVVQLVLNFLQELEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALIARLAAQERYSSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRHMNRIIEINPEEGWVRVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGVRAVLLGGDILDTQPLPVELAETLGKSNTTIGRIYNTVY
                     QRCRQQRQLIIDNFPKLNRFLTGYDLRHVFNDEMTEFDLTRILTGSEGTLAFITEARL
                     DITRLPKVRRLVNVKYDSFDSALRNAPFMVEARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDKEMLGLNIVEFAGDDEALIDERVNALCVRLDELIVSQQAGVIGWQVCREL
                     AGVERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDSHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQEILMKQISDDVVALTAKYGGLLWGEHGKGFRAEY
                     SPAFFGEELFAELRKVKAAFDPHNRLNPGKICPPEGLDAPMMKVDAVKRGTFDRQISI
                     AVRQQWRGAMECNGNGLCFNFDARSPMCPSMKITQNRIHSPKGRATLVREWLRLLADR
                     GVDPLKLEQELPESGVSLRTLIARTRNSWHANKGEYDFSHEVKEAMSGCLACKACSTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPLRDHLVATVESYAPLMARAPKTFNFFINQPLVR
                     KLSEKHIGMVDLPLLSVPSLQQQMVGHRSANMTLEQLESLNAEQKARTVLVVQDPFTS
                     YYDAQVVADFVRLVEKLGFQPVLLPFSPNGKAQHIKGFLNRFAKTAKKTADFLNRMAK
                     LGMPMVGVDPALVLCYRDEYKLALGEERGEFNVLLANEWLASALESQPVATVSGESWY
                     FFGHCTEVTALPGAPAQWAAIFARFGAKLENVSVGCCGMAGTYGHEAKNHKNSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRVEGTGVRHPVQALLEIIK"
     gene            38430..38840
                     /gene="menI"
                     /locus_tag="ACHY1N_002533"
     CDS             38430..38840
                     /gene="menI"
                     /locus_tag="ACHY1N_002533"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HFS4044828.1"
                     /translation="MIWKRKITLEALNAMGEGNMVGFLDIRFEHIGDDTLEATMPVDS
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKVVGLEINANHVRSAREGRVRGVC
                     KPLHLGSRHQVWQIEIFDEKGRLCCSSRLTTAIL"
     gene            38940..39128
                     /gene="ydiH"
                     /locus_tag="ACHY1N_002534"
     CDS             38940..39128
                     /gene="ydiH"
                     /locus_tag="ACHY1N_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiH family protein"
                     /protein_id="HFS4044829.1"
                     /translation="MSTQLDPTQLAIEFLRRDQSNLSPAQYLKRLKQLELEFADLLTL
                     SSAELKEEIYFAWRLGVH"
     gene            39676..40044
                     /gene="sufA"
                     /locus_tag="ACHY1N_002535"
     CDS             39676..40044
                     /gene="sufA"
                     /locus_tag="ACHY1N_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HFS4044830.1"
                     /translation="MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLG
                     VKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQI
                     FKFHNPKAQNECGCGESFGV"
     gene            40053..41540
                     /gene="sufB"
                     /locus_tag="ACHY1N_002536"
     CDS             40053..41540
                     /gene="sufB"
                     /locus_tag="ACHY1N_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416198.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFS4044831.1"
                     /translation="MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVR
                     AISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDT
                     CASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKN
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            41550..42296
                     /gene="sufC"
                     /locus_tag="ACHY1N_002537"
     CDS             41550..42296
                     /gene="sufC"
                     /locus_tag="ACHY1N_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFS4044832.1"
                     /translation="MLSIKDLHVSVEGKAILRGLSLAVRPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTGGTVEFKGKDLLALSPEDRAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHV
                     LYQGRIVKSGDFTLVKQLEEQGYGWLTEQQ"
     gene            42271..43542
                     /gene="sufD"
                     /locus_tag="ACHY1N_002538"
     CDS             42271..43542
                     /gene="sufD"
                     /locus_tag="ACHY1N_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFS4044833.1"
                     /translation="MAGLPNSSNALQQWHHLFEAEGTKRSPQAQQHLQQLLRTGLPTR
                     KHENWKYTPLEGLTNSQFVSIAGEISPQQRDALALTLDAVRLVFVDGRYVSALSDATE
                     GSGYEVSINDDRQGVPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPAKPFLLMHITQG
                     VAGEEVNTAHYRHHLDLAEGAEATVIEHFVSLNDARHFTGARFTINVAANAHLQHIKL
                     AFENPVSHHFAHNDLLLADDATAFSHSFLLGGAVLRHNTSTQLNGENSTLRINSLAMP
                     VKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVAQHAIKTDGQMTNNN
                     LLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQMFYLRSRGINQQDAQQMIIYA
                     FAAELTEALRDEGLKQQVLARIGQRLPGGAR"
     gene            43539..44759
                     /gene="sufS"
                     /locus_tag="ACHY1N_002539"
     CDS             43539..44759
                     /gene="sufS"
                     /locus_tag="ACHY1N_002539"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
                     /protein_id="HFS4044834.1"
                     /translation="MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDSEA
                     EFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVA
                     NSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPNL
                     FDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCD
                     FYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEA
                     GTPNTGGIIGLGAALEYVSALGLNSIAEYEQNLMHYALSQLESVPDLTLYGPRNRLGV
                     IAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVD
                     RLVTGLQRIHRLLG"
     gene            44772..45188
                     /gene="sufE"
                     /locus_tag="ACHY1N_002540"
     CDS             44772..45188
                     /gene="sufE"
                     /locus_tag="ACHY1N_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HFS4044835.1"
                     /translation="MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRAEDRSP
                     QNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS"
     gene            45337..46341
                     /gene="ldtE"
                     /locus_tag="ACHY1N_002541"
     CDS             45337..46341
                     /gene="ldtE"
                     /locus_tag="ACHY1N_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtE"
                     /protein_id="HFS4044836.1"
                     /translation="MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTV
                     QEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNL
                     AELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLER
                     GIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIK
                     ALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQ
                     FKDNKAVDQKLVDKALYRRAGYPVSVSSGATPAASNAPSVESAQNGEPEQGNMLRATQ
                     "
     gene            complement(46405..46641)
                     /gene="lpp"
                     /locus_tag="ACHY1N_002542"
     CDS             complement(46405..46641)
                     /gene="lpp"
                     /locus_tag="ACHY1N_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein lipoprotein Lpp"
                     /protein_id="HFS4044837.1"
                     /translation="MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQL
                     SNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK"
     gene            complement(46952..48364)
                     /gene="pykF"
                     /locus_tag="ACHY1N_002543"
     CDS             complement(46952..48364)
                     /gene="pykF"
                     /locus_tag="ACHY1N_002543"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase PykF"
                     /protein_id="HFS4044838.1"
                     /translation="MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGN
                     SEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMTSRLDFNNDSRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAQKGDVVV
                     MVSGALVPSGTTNTASVHVL"
     gene            complement(48372..48566)
                     /locus_tag="ACHY1N_002544"
     CDS             complement(48372..48566)
                     /locus_tag="ACHY1N_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010283910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4044839.1"
                     /translation="MDCRTQRLKNRHSRWAETQAHIPLHAFSMSPILRARHHHFRNTG
                     FAFRQCAQKASFSHPSQLKD"
     gene            48921..49130
                     /gene="fumD"
                     /locus_tag="ACHY1N_002545"
     CDS             48921..49130
                     /gene="fumD"
                     /locus_tag="ACHY1N_002545"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase FumD"
                     /protein_id="HFS4044840.1"
                     /translation="MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTA
                     LANKRIQRSELEKQAMETVINALVK"
BASE COUNT        12234 a        11936 c        12672 g        12447 t
ORIGIN      
        1 cgtctggttg gtgtcgtcat tggtttactc cttgtccatt gcgtacagcc cattaaccag
       61 agcaaactgt ggcaccccgt ccgcgatgaa agtcgcatta actccgcagg cttcgcggat
      121 agcgggtgcc acaatctccg ccccgccacc gacaaccatc acccgcccgt aacccgaaaa
      181 acccgccagc gcgcggatca cgcgttgttt cagtgtttct tccttttcac gaataaccgc
      241 catcaggctg gcgtaatgcg cgtcattgtg gatgtgctgg cgcagccagg cttcatcatg
      301 gcgatgttcg ataatggtat tggcgatgtg gtgactggta cgcataccgt tagtggccat
      361 caccgacagt acggcatcgg ccatcaggga aacgcctacg tgtggatcgc aaaacacctg
      421 gctgatacct gccagttgtc cctgaacctt tgccacatcc agcgtggttc cgcctaaatc
      481 cacaatcagc agggattcaa acggactcat gtcagccagt gctttaaaac cagccggaat
      541 ggattcaggc ataacccgta cgttacggat agtgaatgct tttccgttct ggtacgccac
      601 cgggcgcatg acgtttgctt ttttgcggtt gatgttggcc atgtccggct gtgcgtttgt
      661 gtcgaaatat tcgctcagtg gcagggtgac aaccacatcc acctcctgtg gtgtgatgcc
      721 tgatttgacc agcgcgtgat gaatggcaat gacattcaca tcgctgtact ggtattgcgt
      781 gtcggtcgtc tggacaaagc gatcgctgac cggatcaaaa ccatagcgca cgccatcaag
      841 catgtagttc gcgggctgcg tgccaccgaa cggcgcagac cattccgact tgaagctgtt
      901 cgggctgatg gcgttgcggc gttcgccgtt ctcagtccat gccagcttga tgttggtgga
      961 gccgtcatcg atacaaattt tcatgtcgct tttccttatg ttgattaatt aatcgtttac
     1021 gggattctga aatcccgttt ttgcctgttt tatgcgcgct tcatatatcg cggcgcgttt
     1081 tttgctcatt tacgggattt gtgaatcccg tttctgtctg ttttttgttt ccactggtca
     1141 ggccaccccg cagcaggtct gctttgcggc gggcgcgttc agtggtttca ctgattctct
     1201 gtgcgtgctc tgcgtcgcgg atggcgcgca gcatgtcaga aagcacggta acgggtgttt
     1261 tcatggtgtt ctggtcctgc tgaagtgtgg atgccaggcg tgcggcggct tcggggtctg
     1321 atgtccccag ctgttccaga tagctggcga ccgggttatg gcggatctcc gtactgctta
     1381 cgccgtggtt acggctcagg cgctgccaga gctgcgtgat ccggctgtcc ggtcgggtat
     1441 ccggtttgcg tacaatttca aatccctgcg gtgcaatgat gctgccgtca acgtacagac
     1501 tgccgccccg taacagatgc tgcatctgct gttcaccgat atgcaggccg agagattcag
     1561 cagactcccg ccattcttta gcgagtagtt cgtggttatc aggcaaaggc cgctgctgtt
     1621 tgcggctctg tgtccagctc tgcatttcat cacggctgtt ttttgcctgt ttgtcacgaa
     1681 gcgaacgcat cagcgcccgg cgttcgtgcc gtttcagtga gcgcatccat tcgttcactt
     1741 caacgccgtc agggagctgc gaccacggtg ctggctgttc ttccggctgt tctgtcccgt
     1801 tgttgtccgt ttcctgtaca cggggacagt tattgccacg agtccaaggg gcggcagggc
     1861 cgccctgaag gtcaaaacca ttttcgcggg tgctgtcttc cgcttccggt ttacgtctta
     1921 ccagcttcca gttatccggg tgcgtgcaca cacgggagga ttccccgatg agtggtgacc
     1981 agatcccgta aatctgtacg ctctgttcgc cgtaatcgtt cagctcatct gcgaggtcgt
     2041 aggcggtgcg aatcaggtag tctttgcgtg gaacaagtac gccgccctgt ttctcaatgt
     2101 aggtggcaaa acacccggca tcagcggcag cgagtaccgc atccattgca tcatccttca
     2161 gccgttgtgg gccttccggg ttgcgtgcca tctggctggc aaggcggcgg agttcacgcc
     2221 atacctgacg ggaggggatg ccaaagaact ggaactggcg gacccggtga aggcgtgccc
     2281 agccgatggc gcgttccacg ctctcggcca ttgattttcc ggtttcgtgg tcaacgcgtg
     2341 gcttgcccgt tttcgggtca atgccatcca cggcgcggct gtccaggttc tttccgatgt
     2401 aggtggcgat gtagctggtc ggcgtacctt tcgaaccgtc gacgtactct gccttaaagc
     2461 gcggagttat gtcattgccc agctcgtggc ggtcttcgcg aatggcaata tcacgggtga
     2521 tgtccacgat gctgtcgatt tcttcaggat gtgcaaagac catcatgtgc cagtgcacgg
     2581 tgccgtcatg gtgtggctcc accgtgcgga tgccatacca gcgcaggccg tcgcggttca
     2641 gttttttgcg gactgcctta aaaaaagtgt taaccaggta atcgctggaa tcgcgcatgg
     2701 tggcgccgtt ccatttggga ttcggatgac cgttctccgt tgttgcgtga tattttgacg
     2761 ggcaggtgac agtcagaaac actgctctgt cgtcacgggc ttcggccaga agttccagcc
     2821 ccttcatggt ggccatcatt tctgccttac ggtggaccgg gttacttact cccgcgtaat
     2881 acaccgtctc gagatcaatc gtgaacccgt cttcattttc cagcatgaaa cttttcagga
     2941 aatcgcgtgt tttctcgcgc tgtgcgcgaa attcgcttaa tgcgtcctga ctcagatagg
     3001 gggatgtttt tctggaaacc agacaggcag cgcggagttg ttcctctctc cattcgcaac
     3061 gtaaaagcca caatttgcgt ttccaccagt ccgcacaggt caggcggagg attgcacccg
     3121 gcagcagctc cgtgtccggt tcgttcttcc ggtctttgtc tgttgtcagt gcgtcataat
     3181 gcggcggcac tgtgtgcaga tgtaacgcca tgcgggccag catctgatat gccttcagcg
     3241 ttatatccat ggtcagctcg ccatcggtcg cgccaaagtc atcgcagagt ttttcgaagg
     3301 tgctgctgaa catcgccgct gtcatgacgg ccagtgtctg tatctggtgt ttgttgagct
     3361 gcggcaggta aagtaaatca tccaggcgtt cacgcccggc aagggagcga taacccggtg
     3421 tcagccagcg tctgtcggtg cgctccagac gttcgaatat tttgcgcagg gttccgcgcg
     3481 cgtagcgttc agcctgccag ctctttttgc ctttctgacg atcggattcc tgttttttgc
     3541 gcaggaaaga gagatggcgg ataagcggat cacgcagata ggacggcagc agacgcagtg
     3601 cggcaattgc ttcatccacc gcgccgcgtg cctgttttct ggcttctctt gccagtgtga
     3661 tggctttgtc ctgtttttcc tgtgcgtcca ggcttttatt aatcagattg cccagcggtg
     3721 cggcagagaa cgccgcatca gccatttcct ggcggcgctc gttctctgcc cggtaggcat
     3781 ccagccagga agaaagaagg gagggacgga caggctcccc cgtcccctcg cgaccgactg
     3841 catggcgtgg ttgttgccag tttctgatgt actccgttgc cacgccgact actccgcctt
     3901 tccgctcagt gcattgtggc agacggtagc cagccgctgg atttcctgca tggtgctctc
     3961 tgtgctggca taacggtgtg ttatgcgaat gctgtcagca attacatcag caatcagaga
     4021 tgaagttcgc tggtaaatac ccagtacgga aggcgtgccg ctttcgatgc gggaaagtgt
     4081 gtaatcatcc tggcagctac caaccatgta gcgcccgtca ataacaatct ggccgtccgg
     4141 gagctgctgt tccggcagtg atttcagata cattgcatag cggtcgagaa cgcgaatacc
     4201 aaaatcgcgc tcggttttca gtaggtaatc aaaaaagtct tcggcgagaa tcattgcggc
     4261 aatcctcttg ttgcagatgt gcgaaggcct cccgccgcaa ggtgcaggaa aggcccggaa
     4321 caggaattaa cggagtttgt tttgctgccg gatgagctgc tgaagcccga cgtggtttcc
     4381 ggcagttgga ggtgctcatg ctctgatttc cctcagtagc tggttaaaca tgtgagtaag
     4441 tggattgcta cacccgaacg gcatcgggtt tacgtggtaa gaagcctggc ctcctgtttt
     4501 gcgagcgcga ccacctgtgc tgcggtttgt tctgatgact aagccgccgc gccaaagtcg
     4561 gcgtaactca gcattaatgg ctgtggttgg agtattcagt gctgcggcga tctctccgcc
     4621 gctacacccc ggatgagtag cgatgtagtc cagaatggtc atctgcgtgg ctcctgtacc
     4681 tgtcggataa gatttactcg cgccacgttg gtggcgcaga agtaagtgcc gtcagtgaga
     4741 tagatgtggt gtgcatcctt ttccgaacga tgtttgtcga tagtggtaat caggcgttcg
     4801 tcgacttcgt attcacgtcc tctggaggta aaacgaacga caggaaaatg cttaattgcc
     4861 attacgcctc cttggtgtgt gcgaatacct ccgcgaatgc ggattgtttt cacattttct
     4921 tatttaacct ggagtcttat ttgcgcggtt attcttcagt aaaaaagcgt tcaatctttt
     4981 ttactgaatt aataattcgc ataatcccaa tagcgcaggc caccgaaata atcagaacaa
     5041 gccatgagat aaatatactc atgcaatatt ccccagttta tatggctcaa tatggtcccc
     5101 gttttctgcg gcgcagacga gtacggaaag ctcgtcgagc gcgtccgggt cgtcaatgta
     5161 aaaagctgtg tcgtatatac tcttgatggc cctggtcaat gattctcggg ctgcgagctc
     5221 agcatgagtg cctgatgcgc ttaagcgaaa atgaaagcgc tcaagtgctt tattgacgag
     5281 agttttatat tctttatcca tcgcaacgcc ctttaatctg ccttctgaat ttcagcttct
     5341 gaatccatgc agataatttc gagatagggt ttattgccat taacctgacg tgctttttca
     5401 gcttcgctaa taatttcgca tacgtgttga tatggaatct ctacggtcag gcgtgtgccg
     5461 ttcagataaa tgtaagtggc cgtgctttta tctaccggaa ccactccatc aatagctgat
     5521 gcgcgcaaca acagctcacc gcgaaaatca ataaagcgga taaatacacc ctgagcatgg
     5581 tctttggtca taaagcacct gttataaatc agcctgttta atgaaattct gtccgcgcag
     5641 cagacgatca accgtgcgca gagcttcgta caacgtgaaa tcctgtccaa actgattgtc
     5701 gccgttgctc agagcaaaaa tgcggtttcc ggtaaatggg ttgcgctggc atctgtgaac
     5761 cacgattcca gctttctcaa tcagccaagt gtgttcacca atttgtttta cggggtgacc
     5821 atccggtgtt gcgtgtgtct cgctcaggct gtagcgggag ttactacgtg atgcactggt
     5881 agcgaaacgg ttagcgtggc gttccgttcc ggtaaaaaaa ttacggcgtt gcttcagcat
     5941 aaaattacac ctcgttattt tgtcatctgc acgtatttct ctgcgtttct gatggttttc
     6001 aggaaaattg cgaagagatt tactgtacgt tttgagtttt tttcttcttg gttgatggga
     6061 agggctgctc tgtcagcctg ccttttcact gcattaacag tttgattggt acgcttcgcg
     6121 taatctttca ggctttcttc gagtaccggt aatccatgct catcgcggta tgggtagaac
     6181 gccgccaaac gctcaaaatc cgcttgctcg tatgtgttca agagctttgt catgatgtga
     6241 taacctgttc agtctgtggt tatttgttgc taaaagtcgt ctctaggcga cttttagggt
     6301 taatttagtc gtctggagac caccatgtca agtgggtacg aaaaaaaact gaaagagata
     6361 cggaaaagtg aagggttaac tcaagctgag tttgctgatg ttactgggat aaatctcgga
     6421 actataaaga attatgagag cggtaaaaga gaggttggtt taagcgttgt tgatcgcgta
     6481 attaattcta aggatttcga aaaatacact atatggctta tgacgggaaa aacaaatgag
     6541 gctgcagggc agatcagtcc ctctctctcc cctgatgggc cagaaaacac atcgtcttct
     6601 caaaaatccc gcaagactgg cacacagccc ggctaatcat ggaacgctgg gggcatggtg
     6661 gtcttgtaac gctggggttt cacgaatgag cataaaatca attccgggag gttatcttct
     6721 tgacatgcgt ccagaggggc gcaaaggcaa gcgcattcgc aaaaaattta aaacgaaatc
     6781 ggatgcagtt ttatatgagc ggtgggtgct ggcgcaacag cataacaatg agtggaaagg
     6841 aaactctatt gatcgccgtc ctctgtcagt gcttattgaa ttgtggtgga aataccacgg
     6901 ccagctaatg aagtcagggc ataacacgcg tcttaaattg ctgcgcttga gtgaggtaat
     6961 ggatgacccg tgcgtgcata aacttaatac aacgatgctc accgagctgc gtgtgtccag
     7021 gatagagcag gggatacagc ccagcaccat taatcgagag attggggcgt taagcgcgat
     7081 gtttaccgca ctcatctcat ccggccattt tcttaacgat aaccccgttc aaggccttaa
     7141 aggaatgaag gttaacgagc gcgaaatggg atatctgagt aagtctgaat gtgttcagtt
     7201 gctggatgca ctggctgaaa atcccgatga acggctggct gtcgaaatcc ttctgtcgac
     7261 cggggcgcga tggggcgagg tagcggcact ggagcagcgc cgtgttcttc attgtcgaat
     7321 cactttttca aaaacgaaga acagcaaaaa ccgtaccgtt cctatttctg aaagcctgtt
     7381 tgaaaagatc aaaaaacggg gcgggaaact ggtgtttccg acgctggatt atccattggt
     7441 tcgcgatgtc atcaaaacgg tcgcacctga tgttcctgac ggccaggctg ttcatgcgct
     7501 gcgccacacc ttcgccagtc atttcatgat gaacggcggc aatattctga cgctccagaa
     7561 aattctgggg cacgcaaaga ttcagacaac gatgatttat gcccatcttg cgccggatta
     7621 cttgcaggat gcggtgaggt ttaatccctt gggaggaatg taactatgga aataaaaaaa
     7681 cctacaaaaa aagagttata tgactattta ctatcgaaat atatagaaga taaatgcaaa
     7741 gaagaagctg atgaaatcaa taagaagtcg atgagtcgtg tcaaaaaaca taaagagcgg
     7801 ctgatggaga ttacgccaga aatcttcttc cgtttcttgt ctgagaaggg ggtctccagt
     7861 gtctgccctt catgtggatc gtcgcgatta tctgttcccg aaagtatgga tctttgctgg
     7921 gataaaaata agaaaccaga aaattttaac aatctacccc tggaggagca gagtgagtta
     7981 attaaagaga acataaagca ttatgtatct tatacttttt tgggtgatgt taagagcata
     8041 cctgatatgc gcaaaactta ttacacgctg cattgcctga attgtggtta cctgagcctt
     8101 tatcgtacgt ctgcggtgct gaagtggttg gagaaagaca aagcgcagga tggtgataat
     8161 gggtaatgta gcaagaaatc ttttcggtaa ttcagcaggt agtgtgtcgc attctgagcg
     8221 tgatgtgctt tatcatggtg gcgatggcgg cagtagtgga ggcggaatgt cagataaact
     8281 tgaaaggcga attgagcggc tcgaaggtga tttatcgcta acaagaaacg accttgcgac
     8341 gcttgctgaa cgcactacaa acctctcaac taaagccgat gttggtgagg tgaaaggtga
     8401 acttaaagca gacatagcac atctgaaagg tgatcttgaa tgcggtattg cgaatctgaa
     8461 aggtgagctt aaatctgata cagctaacct gaaagagcag ctcaaatcag acattaacag
     8521 cctgaagggg gagattgccg aagcgatgga taaacgcttt gacaagatta tggatgagat
     8581 gaatcggcgg tttgacaaag ttgatgataa tacgaagtgg cggttgagtg gcatcattat
     8641 acctgtatgt atagccatct ttacttcgct ttttacagcg gcggctacgt atttcattgc
     8701 aaaatttgtt ggctgatgat ccacaaagtg accacatcac tgttacttgt tgtggttgac
     8761 tgtgtttttg tgtgtctgta agttattgat aattatttaa cttgttgatt tttgaatgtg
     8821 attatggccg ctctgcggcc ttttttcttt tcactgtcga agagtcaccg taaaatcaac
     8881 gccatgacac ttcagcagaa cggataccat gctgacactt gcccgccaac aacagcgaca
     8941 aaatattcgc tggttattat gcctgtcagt tttgatgctg ctggcgcttc tcttaagcct
     9001 ttgcgccggt gaacaatgga tctcgccagg tgactggttt actcctcgtg gcgaactgtt
     9061 cgtctggcaa attcgcctgc cacgtacgct ggctgtattg ctggttggtg cggcgctggc
     9121 tatatccggc gctgtaatgc aggcgttgtt tgaaaatcct ctggcagaac ctggactact
     9181 tggcgtctct aacggcgcag gcgtggggct tatcgccgcg gtattgcttg ggcaagggca
     9241 actccccaac tgggcgctag ggctgtgtgc gattgctggc gcgcttatca tcactttaat
     9301 actcttacgt ttcgcccgtc gtcatctttc gaccagtcgg ttattgctgg ctggcgttgc
     9361 attagggatt atctgtagcg cactaatgac gtgggctatc tacttttcca cctctgttga
     9421 tttacgtcag ctgatgtact ggatgatggg cggttttggc ggcgtagact ggcggcaaag
     9481 ctggctgatg ctggcattga tccccgtgtt gttgtggatc tgttgtcagt ccaggccgat
     9541 gaatatgtta gcacttggcg agatctcggc gcggcaactg ggtttacccc tgtggttctg
     9601 gcgcaatgtg ctggtggccg cgaccggctg gatggttggc gtcagtgtgg cgctggcggg
     9661 tgctatcggc tttattggtc tggtgatccc acatattctt cggttgtgtg gtttaaccga
     9721 tcatcgcgta ttacttcccg gctgcgcgct ggcaggggcg agcgcattgc tgctggccga
     9781 tattgtagcg cgcctggcat tagctgccgc agagctgcct attggcgtgg tcaccgcaac
     9841 gttgggtgcg ccggtgttta tctggttatt gttaaaagca agacgttagc cgcaaaaaga
     9901 cggtctatga ttaaaagcta agatttttac tgaccacacc caggagaaac gatgcaagat
     9961 tccattctga cgaccgtagt gaaagatatc gacggtgaag tgaccacgct ggagaagtac
    10021 gctggtaatg tgctgttgat tgtcaatgtc gcctcaaagt gtggcttaac gccgcaatat
    10081 gagcagttgg agaatattca gaaagcctgg gccgatcgag gttttgtggt gctgggattc
    10141 ccgtgcaacc agtttctgga acaagaaccg ggcagcgatg aagagattaa aacttactgt
    10201 accaccacat ggggggtgac gttcccgatg ttcagtaaga ttgaagttaa tggcgaagga
    10261 cgccatccgc tgtatcaaaa attgattgcc gcagcgccga ccgcagtcgc gccggaagag
    10321 agcggattct atgcccgtat ggtcagcaaa ggtcgtgcac cgctgtaccc tgatgatatt
    10381 ttatggaatt ttgagaaatt tttagttggc agggacgggt tggtcatcca gcgtttttcc
    10441 ccggatatga cgcctgaaga tcccattgtg atggaaagca ttaaactggc gttggcaaaa
    10501 taatgtctat tgtgatgcag ttacaggatg ttgcggaaac tacccgcctg gggccgcttt
    10561 ctggcgaggt tcgggctggg gagatcctgc acctggtggg gccgaatggc gcgggtaaga
    10621 gtaccttgct tgcacgaatg gccggaatga ccagcggtaa gggaagcatt cagttcgcgg
    10681 ggcaaccact ggaagcatgg tccgcaacaa aactcgcgct gcatcgcgcc tacctttcac
    10741 aacagcagac gccgccgttt gcaatgccgg tctggcacta cctgacactg catcagcacg
    10801 ataaaacgcg taccgaacta ctgaatgatg tcgcaggggc gctggctctt gatgacaaac
    10861 tcggacgtag caccaatcaa ctttccggcg gtgaatggca acgcgtacgt cttgctgcgg
    10921 tggtgctgca aatcacacca caagccaatc ccgcaggtca attgctgctt cttgatgagc
    10981 cgatgaacag tcttgatgtt gcgcaacaaa gtgcgttaga caaaattctg agcgctctgt
    11041 gtcagcaagg actggcgatt gtgatgagca gtcacgatct caaccacaca ttgcgtcatg
    11101 cgcatcgggc gtggttgcta aaaggtggaa aaatgctggc cagtggacgc agagaagagg
    11161 tgctcacgcc gccaaatctg gcgcaggcct atgggatgaa ttttcgccgt ctggatatcg
    11221 aaggtcacag aatgctgatt tcgaccatct gatttcatta gtatcttgaa aatcgggtaa
    11281 ttacgacgct aaattaatgc aagaataaaa aacagaggaa ccgtacggaa tgcgtttctg
    11341 ccttattttg atcacagcac tgtttctggc cgggtgtagc caccataaag caccgccgcc
    11401 aaatgccaga ctttctgatt cgattaccgt tattgccggt ttgaacgacc agctacaaag
    11461 ctggcatggc acgccgtatc gttatggtgg catgacgcgg cgcggtgtgg actgttcggg
    11521 atttgtggtt gtaacgatgc gcgatcgttt cgatttgcag ctgccccgag aaaccaaaga
    11581 acaagcctct atcggcacgc aaattgataa agacgagttg ctgcctggtg acctggtctt
    11641 tttcaaaacg ggttccggac aaaatggttt gcatgtaggt atttacgata ccaacaacca
    11701 atttatccac gcctctacca gcaagggagt gatgcgttcc tcacttgata atgtctattg
    11761 gcagaaaaat ttctggcagg cgagacgaat ttagtatgtc gaaaaatgga cggcgatgat
    11821 acatcgccgt ccatttactc ctgaatacag tagtattttg cagacaaaaa ttccgtaaat
    11881 ggattattcg tttataatca ggataatcta aaaaaaggac ccctgaaaaa gtggttaaca
    11941 tggaacaaat gaaagttact ccttctgtaa ttgttatgtc ttatggcctc atccctttta
    12001 gccggatact gaaaaacatc cttcgagagg gacggttacc atgaagattt ttttggagaa
    12061 tctttatcat tctgattgct atttcctgcc gataagagat aaccagcaac tccttgtcgg
    12121 cgttgagtta attacccatt tctccagtga agatggcacg gtgcgtatcc cgacgagtcg
    12181 ggttatagcg caacttaccg aggagcaaca ttggcaatta ttttcagagc agttggaatt
    12241 actaaaatca tgccaacatt tttttattca acataaactc tttgcctggc ttaatttaac
    12301 gccacaagtg gctacattat tattagagag ggataattac gcaggcgaac tattaaaata
    12361 tccgtttatt gaactgttga ttaatgagaa ttacccgcat ctcaatgaag gaaaagataa
    12421 tcgcggtctt ttatccttat cgcaagtgta tccccttgtg ttaggtaatt tgggagcagg
    12481 caatagcaca atgaaagcgg tttttgatgg tcttttcacc cgcgtcatgc tggataaaag
    12541 ttttattcag caacaaatca cgcaccgctc cttcgaaccg tttattcgtg cgatccagtc
    12601 gcaaatttcc ccttgttgca attgcatcat tgcgggaggc attgatacgg cagaaatatt
    12661 ggcacagatt acccccttcg atttccatgc tctccaggga tgcctgtggc ctgccgttcc
    12721 cataaatcag ataacgacgt tggttcagcg ataacccttc tgtttgctgg tgtttaagac
    12781 gagagtaacc gtctacacta tcaaacagga ggatctatga ccctgtcttt tattacccgc
    12841 tggcgcgatg aattgccaga aacctataca gcactttccc ctacgccttt aaataatgcc
    12901 cggctgattt ggcataatac cgaactcgct aacacgctga gtattccatc gtcgctgttt
    12961 aaaaatgctg caggtgtctg gggcggcgaa accctactgc ctggtatgtc accactggcg
    13021 caggtttaca gtggtcatca gttcggcgtc tgggcgggcc aactgggtga tgggcgcggc
    13081 attttacttg gcgaacaact gcttgctgat ggcactacaa tggactggca tctgaaaggt
    13141 gctggcctga cgccttattc gcgaatgggt gatggacggg cggttttacg ttcgacgata
    13201 cgagaaagtc tcgccagtga ggcgatgcat tatctgggca ttccgacgac ccgcgcgtta
    13261 agtatcgtca ccagcgattc gccagtgtat cgggaaacgg tggagccagg cgcgatgctg
    13321 atacgtgtgg caccaagtca tctgcgcttt ggtcatttcg aacattttta ctatcgccgc
    13381 gagccggaaa aggttcgtca gttagctgac tttgccattc gtcattactg gtcacatctt
    13441 gaagatgatg aggacaaata ccgtctctgg tttaacgatg ttgtcgcacg taccgcatcg
    13501 ttaattgccc aatggcagac ggtcggcttt gctcatgggg tgatgaatac cgacaacatg
    13561 tcgctgctgg ggctgacgct tgattacggg ccgtttggtt ttcttgatga ttacgaaccc
    13621 ggttttattt gtaatcactc ggatcatcaa gggcgttaca gctttgataa tcaacctgcc
    13681 gtcgcgttgt ggaatttaca gcgtctggcg cagacattgt caccatttgt tgccgtagat
    13741 gccctgaatg aggccctgga cagctatcag caggttttgt tgacgcatta tggacaacgg
    13801 atgcggcaga aactgggctt catgacggag caaaaagagg ataacgcgct actgaatgaa
    13861 ttattcagtc tgatggcgcg agagcgcagc gattataccc gcacattccg catgctgagt
    13921 ctgaccgagc agcacagcgc ggcgtcaccg ctacgtgatg agtttattga tcgtgcggca
    13981 tttgatgact ggtttgcccg ttatcggggg cgtttgcaac aagacgaggt tagcgatagt
    14041 gagcgtcagc agctgatgca aagcgttaac ccagctctgg tgttgcgcaa ctggttggcg
    14101 caacgggcga ttgaagcggc agaaaagggt gatatgacgg aattgcaccg cctgcatgag
    14161 gcgttgcgaa atcctttcag cgacagagct gatgactatg tcagtcgtcc acctgactgg
    14221 ggtaaacggc tggaagtcag ctgctcgagt taaaggctac ttggtcaaca gcagcttgcc
    14281 agcctgagtt ttacggagca gatattcttg cccgtcatga tcgataatca gtttgccatc
    14341 cggacctaac agtgtctggc tggaaattcg ccgaataggc tgcggggaag cggtcttgtg
    14401 attggcatcc gtttcaggcg tgagttttct gctatccgta taacgcataa aaattaataa
    14461 taattgatat aacaatgatt cttattatca atattatggc tgaccagagc aagcagtaat
    14521 gtgctgagaa gacaacaagt tgcgcagaaa tgcccatccc atcaggaatg ggcacgcatt
    14581 cagaagcggg tatctaccgc agaggcaagt ttttcgacca ggcgttcggt atcttcccag
    14641 cccagacacg ggtcggtaat ggattgaccg taagtgagcg gctgaccgcc gacgattttt
    14701 tgcgttcctt cgcgcaggaa actttccgcc ataattccag caatcgccgt agagccattg
    14761 cggatttgct gacaaatatc ctcacaaact tctaactggc gacggtgctg cttctggcag
    14821 ttaccgtggc tgaaatccac caccagatgt tcaggtaaat caaactcgtg cagcgtatcg
    14881 caggctgcgg cgatatcatc ggcatgataa ttcggttttt tgccgccacg cataataatg
    14941 tggccatacg ggttgccgct ggtctgatag atggtcatct gaccattttt gtctggcgag
    15001 agaaacatat ggctggcgcg ggctgcgcgg atagcatcca cggcaatccg cgtgttgcca
    15061 tcggtaccat ttttaaaacc taccggacag gagagtgccg aagccatttc acggtggatc
    15121 tgactttcgg tagtacgtgc gccaatcgcg ccccaactga ttaaatcagc aataaactga
    15181 ccggtcacca tatcgaggaa ctcagtcgcg gtagggacac ccagctcatt tacctgtaaa
    15241 agtaatttgc gcgccagctc cagaccgtga tttacccgat agctgccgtt taaatccgga
    15301 tcggagatta gccctttcca gccgacaaca gttcgtggtt tttcaaaata ggtgcgcatt
    15361 acgatttcca gccgtgactg gtactggttg cgcagcgact gcagacgggt ggcgtactcc
    15421 attgcagcgg tgagatcgtg gatcgagcag gggccaataa tgaccaacag tcgcttatct
    15481 tcaccattca gtattttttc aattctgcgg cgggagtcgg tgacatgggt ggcgacgcca
    15541 ggcgttacgg gataccgtag cgcgagttcg gcgggcgtta ccaggctctc aatacgcgca
    15601 gtacggagtt cgtcagttct gttcattaca agtctcagaa atttgttgct tctacggcag
    15661 gactaccggg aagtgatgcg catcacgata aaccaatcgc agctgatttc aagtgcgagg
    15721 tgtgtcacac ctcgccgggt ggttagcatg ataacaaaaa aataagctaa tgcactagtt
    15781 ctctagtgca ttcggcggct aagccccatg atatcgagga tcttggtggc aatctcttct
    15841 accgaataat tggtactgtt aatccacggg atctgatttt tacggtacaa cgcttctact
    15901 tccgcgactt ccatcctgca ctgacgaagc gaggcatagc ggctgttctc ccgacgttcc
    15961 tcgcgaatcg ccgccagacg ttccgggtcg atagtcaggc cgaacaattt atgctgaagc
    16021 ggtttgagcg acgcgggtag caccagattg tccatatcgt cggcaataaa ggggtagttt
    16081 gccgcgcgga taccaaactg cattgccaga tacagactgg tgggggtttt accacagcga
    16141 gaaacaccga gcaggatcac ctgagcctgg tccagattgc gcaacgaaat gccgtcatcg
    16201 tgggcgaggg tgtaatcaat cgccgcaatg cgcgcatcat atttattgag attattaggg
    16261 ttaaggccat gggtacgatg agcaatcggc gttggatcca gtttcatctc ttgttgtagc
    16321 ggggcaacca gcgcctgaac aatatcctgg caaaagcctt cactttgcaa gatgatggcg
    16381 cgaatctccg gcaacacgat ggagtagaag accagcgggc gcacacctgt ctggtgataa
    16441 attgcgtcaa tctgatcctt cactgcccgt gcacggctct cattttcgac aaacggcagc
    16501 gtaatgctgc tgatagtgac gggaaattgt gacattactg cgtgtcctaa tacctccgca
    16561 gttattgccg taccatcaga aatataaaaa acgtggcgat caacagcatt atccattttg
    16621 ttcttcccgt gatgcagaca taattctatg aaagcataaa ttaaaaacgc acagaagcgt
    16681 aggacgtaat gtctggttta taaaatgaac cttcaatttt attttttatg aaaacagcat
    16741 ttcattttta tggtttcgtt tataccgatg gtttatgtgg aaattgtcga atagagcagg
    16801 tttgcgcaac gctgggatca gtcttaaaaa gtaaaaaaat atatttgctt gaacgattca
    16861 ccgttttttt catccggtta aatatgcaaa gataaatgcg cagaaatgtg tttctcaaac
    16921 cgttcattta tcacaaaagg attgttcgat gtccaacaat ggctcgtcac cgctggtgct
    16981 ttggtataac caactcggca tgaatgatgt agacagggtt gggggcaaaa atgcctccct
    17041 gggtgaaatg attactaacc tttccggaat gggtgtttcc gttccgaatg gtttcgccac
    17101 aaccgccgac gcgtttaacc agtttctgga ccaaagcggc gtaaaccagc gcatttatga
    17161 actgctggat aaaacggata ttgacgatgt tacccagctt gcgaaagcgg gcgcgcaaat
    17221 ccgccagtgg attatcgaca ctcccttcca gcctgagctg gaaaacgcca tccgcgaagc
    17281 ctatgcacag ctttccgccg atgacgaaaa cgcctctttt gcggtgcgct cctccgccac
    17341 cgcagaagat atgccggacg cttcctttgc cggtcagcag gaaaccttcc tcaacgttca
    17401 ggggtttgac gccgttctcg tggcagtgaa acatgtattt gcttctctgt ttaacgatcg
    17461 cgccatctct tatcgtgtgc accagggtta cgatcaccgt ggcgtggcgc tctccgccgg
    17521 tgttcaacgg atggtgcgct ctgacctcgc atcatctggc gttatgttct ccattgatac
    17581 cgaatccggc tttgaccagg tggtgtttat cacttccgca tggggccttg gggaaatggt
    17641 cgtgcagggt gcggttaacc cggatgagtt ttacgtccat aaaccgacac tggcggcgaa
    17701 tcgcccggct atcgtgcgcc gcaccatggg gtcgaaaaaa atccgcatgg tttacgcgcc
    17761 gacccaggag cacggcaagc aggttaaaat cgaagacgta ccgcaggaac agcgtgacat
    17821 cttctcgctg accaacgaag aagtgcagga actggcaaaa caggccgtac aaattgagaa
    17881 acactacggt cgcccaatgg atattgagtg ggcgaaagat ggccacaccg gtaaactgtt
    17941 cattgtgcag gcgcgtccgg aaaccgtgcg ctcacgcggt caggtcatgg agcgttatac
    18001 gctgcattca cagggtaaga ttatcgccga aggccgtgct atcggtcatc gcatcggcgc
    18061 gggtccggtg aaagtcatcc atgacatcag cgaaatgaac cgcatcgaac ctggcgacgt
    18121 gctggttact gacatgaccg acccggactg ggaaccgatc atgaagaaag catctgccat
    18181 cgtcaccaac cgtggcggtc gtacctgtca cgcggcgatc atcgctcgtg aactgggcat
    18241 tccggcggta gtgggctgtg gagatgcaac agaacggatg aaagacggtg agaaagtcac
    18301 tgtttcttgt gccgaaggtg ataccggtta cgtctatgcg gagttgctgg aatttagcgt
    18361 gaaaagctcc agcgtagaaa cgatgccgga tctgccgttg aaagtgatga tgaacgtcgg
    18421 taacccggac cgtgctttcg acttcgcctg cctgccgaac gaaggcgtgg gccttgcgcg
    18481 tctggaattt atcatcaacc gtatgattgg cgtccaccca cgcgcactgc ttgagtttga
    18541 cgatcaggaa ccgcagttgc aaaacgaaat ccgcgagatg atgaaaggtt ttgattctcc
    18601 gcgtgaattt tacgttggtc gtctgactga agggatcgcg acgctgggtg ccgcgtttta
    18661 tccgaagcgc gtcattgtcc gtctctctga ttttaaatcg aacgaatatg ccaacctggt
    18721 cggtggtgag cgttacgagc cagatgaaga gaacccgatg ctcggcttcc gtggcgcggg
    18781 ccgctatgtt tccgacagct tccgcgactg cttcgcgctg gagtgtgaag cagtgaaacg
    18841 agtgcgcaac gacatggggc tgaccaacgt tgagatcatg atcccgttcg tgcgtaccgt
    18901 agatcaggcg aaagcggtgg ttgaagaact ggcgcgtcag gggctgaaac gtggcgagaa
    18961 cgggctgaaa atcatcatga tgtgtgaaat tccgtccaac gccttgctgg cagagcagtt
    19021 cctcgaatat ttcgacggct tctcaattgg ctcaaacgat atgacacagc tggcgctcgg
    19081 tctggatcgt gactccggcg tggtgtctga attgttcgat gagcgcaacg atgcggtgaa
    19141 agcattgctg tcgatggcta tccgtgccgc gaagaaacag ggcaaatatg tcgggatttg
    19201 cggtcagggt ccgtccgacc atgaagactt tgccgcatgg ttgatggaag aggggatcga
    19261 tagcctgtct ctgaacccgg acaccgtggt gcaaacctgg ttaagcctgg ctgaactgaa
    19321 gaaataaaat aaatccccgg cggcgttcag tcgccgggtt tatgtgatcc ccgaagatga
    19381 aacttattca atctcttcac agacatcctg cgttaatcgc cgcataatat cttttcttaa
    19441 caaaaacttt tgtattttac ctgaggcagt gcgcggtagt ttttcgatta ccacgatatg
    19501 ttcaggatat ttatattttg cgacccgttt acggctaaaa aaagccacca cctcttccag
    19561 cgataatgaa tgatgcggcg ctttcagcac gacataagcg catgatcgtt cacctaaacg
    19621 ttcatcgggc attgcaacca cacaggcatc gtgaatttta ggatgctgca ataaaatatc
    19681 ttccacttca cggctgctaa tattttcgcc gccgcggaca ataatatctt ttttgcgtcc
    19741 ggtaattttt atatagccag cctcatccat acggcagaga tcgccgctgt aataccagcc
    19801 ttcttcatcc agcgcacggg cggttaattc aggttcatca aaatatccca taaacacatt
    19861 ggggccacgc gaggcttctt caccttcgca acctggcggt aaggtcttgc gtgcgtcatc
    19921 gaccacttta atctctacac ctgcggcagc gtaaccatcg gtgtgcataa agcgcgacaa
    19981 aggatcatcg agattcacca ccgcatgcgg cgaactttct gtggaaccat aaacacttaa
    20041 taatttaatg ccgagctgct ggcattcacg cgccactttt ttggggattg tggttccgcc
    20101 gcaaagaaag aaacgcagcg ctgacaggtc cgcgggttgt ttctctagta cattcaaaag
    20161 atcatagaca aacggcgttg cgcctagcat acaggtgcaa cgctgctgct caagcagcgc
    20221 gagacacgca tcaggagtga aaatatctaa caacacgctg cgagcaccaa ttaaaaatgg
    20281 tgctgttacg ccatgcagaa atcccgttgc gtgaccaagt ggcgcaggca tcataaagac
    20341 atcctgccag gtcagattca gccgcacgca ataagcccgc tcactggcga gaatattgtt
    20401 atgcgttagc attacgccct ttggcagacc ctcggttccg gaggtaaaca gcaccgcagc
    20461 taattcatcg ccgtgggtcg ttatcgccgt ggtcagtgag gtattgtcgg cgataatctg
    20521 acttaatgag agggaagagg tggcgggagc cagtttgtcc acgccgacaa tttgttgtag
    20581 ttgtggaagc tgattttgca gcggcaggat taaatctacc gggcgcgttt gtttaaacaa
    20641 cgtcggtgca aagaacattt ttgcctgaca cttattgagc acccacacca gttctgcttc
    20701 ccgccaggaa ggcaacagcg gcacggaaac cgcaccgatt ttcaggcagg caagatagat
    20761 aacggtaaat tcacaccagc caggcagttg aaatgcgatg cgatcgcctg attcaatacc
    20821 cttcgctaac atccagtttg ccagacagct cgcggcgtga tcgagcgcgc tataggtgta
    20881 cgatgcacca tgattatcga ccacggcaat tttgtctggc atcgcacgag cggtctgctg
    20941 ccagtaatcg gccagcgaag catcgcccca tagcccttgc tgacgatacg ccgcacgacg
    21001 ttgttcgttg aacgttaatg tcactttcat gttggactct cgaaacagaa catcaggccc
    21061 gagatgcggg cctgtgggat gcatgattag ccgtagcgaa aatcaatacc gaaggtgcct
    21121 gcgggatatt gccactgttc gagaatagtg ttaccgcaca gcacccgaca ggtgccgcac
    21181 tccagacaac cggcagaatc aaaatgaatg ttgccggcgt catcctgctt ataaagtccg
    21241 gcagggcagg ctttcattaa tttacggaat tcattgatat cgggatttgc cgccagaatg
    21301 atatgcgggt ggccctcatc aacatggaat ttattgacgc ctaatttgat gtcgacgtta
    21361 accgtagcgt tctggctcat agcgcggttg ctcccttaat gccatctttc agcaagttga
    21421 tcagcccaat tttcttcgca tgtcccatga tcattttgcg taccggctgg tttggtttgc
    21481 cgtcaatggt gaacatctcg ttcatgatgt cggcgaccat tcgtgggtat tggctaaaca
    21541 ggcgcgggtt ttccatcagc gccgggatct tgcggaaatg ctgcatatcg cgcatgacgc
    21601 agctttgttc cagctcacgt ttgtattgcg ccagactgct ggcggagaaa tcctcgcgtt
    21661 ctttggcggc gatcaccgtt gtggcggcag cctgagccga tgcaatggct aaatccatgc
    21721 cacgaactgt aaaacccaaa ttcaggcaga agcctgcggc gtcaccaacg atcatcacgc
    21781 catcgttaac catctgcggc accattgcca gaccgccttc tggcaccata tgcccggaat
    21841 attcaagcag tttgccgccg ctaattagtg ggcgaatggc ggggtgttgt ttaaaatctt
    21901 ccagcatttg cggcacgctt ttttgcgcat gggcgatatc acccaatcca caaaccagcc
    21961 ccaaggatat ggaatccttg ttggtataga gaaatccccc gcccatcagg ccgtcagaag
    22021 gggaaccggc aaacagccag gcggcacctt cctcgcccgt aatattaaag cgatcgttga
    22081 tctgttctgg tgtgaggcca ataacctctt taacaccaac agcgtaatga tgcggatcgg
    22141 aagcgggaac cattcccagc gagcggccaa gcatcgagtt aacgccatca gccagaatca
    22201 ccacattcgc ttcgagaata tcatccccag cctgcacgcc agtgaccttg tttccttcac
    22261 gaaccagcgc atcgacgcga acgcctggga taaactgcgc gcccgcctgc tcggcttgtt
    22321 ccatcaacca cgggtccaga cgattacgca atacggtata agatgcgtgt tgcggaacat
    22381 ctggttgctc gcggtgaaaa tcgagggtaa cggcgctttc ttcggttaag aaggagattt
    22441 tctcgcgtgt gaccttgcgt tctaccggcg ctgatactgc aaagcctgga atgattgctt
    22501 caagtgtgtg ggcataaaga cgcccgccgg tcatgttttt acatccggca ctgtcgccgc
    22561 gttctatcac caggacatcc agcccggctc gcgccatgac cagtgcggca acgctaccag
    22621 caacgcccgc accgaccaca atggcatcaa atttgtcttc cgacatgcgt tatgctccct
    22681 tcccgctgcg tttacagcgg gagatgtggt tgaaagggga attagcggct caactggcta
    22741 atcagggcag ggacgacttt gtagatatcg cccaccagac cgtagtcggc ataattgaag
    22801 attggcgcat ttttatcttt attgatggcg acaatcactt ttgcgccgtt gccgccaacc
    22861 atatgctgga tctgcccgga gatccccagc gtcaggtaga gatcggattt cagcaacacg
    22921 ccggagacac cgatataacg ttcacgctcc atccagttct cgccttcggc aattggacgt
    22981 gaacagccga cttcagcatt cagcaccgcc gccagttcgt ggaccatttt caggtcatcc
    23041 tgcgccgcca gaccacgacc gacgccaacc acacgttttg ctttgctcag gtccacgctg
    23101 cttgcggctt tcgcacggcg ttcgcgacag agaatttcat gacgcggagc aacataaggt
    23161 accgtttctg tcgggcactg atgagaggta tcactggtgc acggttcctg aacaccgggt
    23221 gcaagggtaa tgatcgccag cgggctgttg atcttttcct gagcgaacgc taacccgcca
    23281 tacatccggt gttcggcgca aatgtgacca tcgataatat ccaccgccgt ggcatcgttc
    23341 accagcgccg cattcagttg cacacttaac cgtgctgcca gagctttacc acgtttcgtc
    23401 gcggccaaca gcaacatagc ggggtgttta tctttcagca gggcagcaat gctttcggcg
    23461 taattttcag tgcgttgcag cgcgtcgttt tgctcaagaa cataaataca ttttggacca
    23521 taaggcataa ctgcctgcgc ctggtcggta ttttgtacaa tggcatacac ctgttggccc
    23581 cattgctgag cgccgccaaa cagttcagca taacgttcag gattatcgct aaagacccag
    23641 acgctgttta attgactcat cgtttcttct ccgtaggctt cagttcaggg ctttcttcag
    23701 atgttccgcc agctcggcaa tggcctccgg cgaatcgtta tcgataatga tgtgcttacg
    23761 ttctgtttgc ggcggtacgc gaatgccgac cagttcagca agtggcgcgc tctggctcca
    23821 gtcaatacca cttgcctgcc actgatttac cggtttttta cccgcgccga gaatggcttt
    23881 catcgaagga atgcgtggca cgttaatatc ggaggtgacg cagagcacgg ctggaacaga
    23941 gagttcaata acttcaacat catcttcaag cgtgcgttca atcaccagtg tattgccctg
    24001 acgctgaata gcactcactg cattaatcac cggaagttgc agaatttctc cgaccagcaa
    24061 gccagcctgc tgggcataaa ggtcgccgga accttcacca aagatcagta aatcgaagcc
    24121 gatcttttca actgctgctg ccagcgcttt tgcggtatcg agaggcagtg catgttcaag
    24181 ttgcgcatcc tgcaccaaat acaggctgtg cggcccgcgg gatagcacgt ctttgcgcac
    24241 tttcgagttc tgcaacaatg agccgccaac ggtcagcgcg gctatctcat cgtcatctgt
    24301 tgcaagctgg cttgcagctt caatggcatt gagatcgaac tggctgattt tggcgtcggc
    24361 attgtcgaaa ttcagggtgt attctggagt gacaacaatg tcctgttctt caggcaccag
    24421 cttaaagcag gttattattt tcatgatttc tcctgtgagt cgcatacgga accatctccg
    24481 atggaaggta aaaatggcct gaaaatagtg tgcgatagcg gtgcggggtt ttcgacggag
    24541 caagctgttt tccttgccaa caatcttgca aaaaaaatgc gatcgctaaa acaaaagtgc
    24601 aatttgcggc aatatagtta ttccatgacc gtacaatctt gcattcagtg taaataatct
    24661 tgtttagctc tcgctaaacg cggttgtata accgcaatac acgccgtatt ttatccggca
    24721 tatattgttt ttgcttgctc atggaatagg gaggttgtca tgtatcaacg ctgttttgat
    24781 aatgccagtg aaacgctgtt tgtcgccggt aaaacgccac ggctttcacg ttttgcaatt
    24841 agcgatgatc caaaatggga gtctggacat cacgttcatg acaatgaaac cgagctgatt
    24901 tacgtcaaga aaggggtagc aaggtttacc atcgattctt cgttatatgt cgcacatgcg
    24961 gatgacattg tggtgataga acgcggcagg ctgcatgcgg tggcctctga cgttaacgat
    25021 ccggcaacga cgtgtacctg tgcgctgtac ggctttcagt ttcagggggc tgaggaaaat
    25081 cagctactgc aaccgcattc ttgtccggta attgccgcgg ggcagggaaa agaagtcata
    25141 aaaaccttat ttaatgagct aagtgtgatt ttgccgcaaa gtaaaaatag ccaaacatct
    25201 tcgttatagg atgcatttgc ctatacgtta gccattcttt actacgaaaa ttttaaaaat
    25261 gcttatcgtt cggagcaggg gtatattaaa aaagatgttc tgataaaaga tattcttttc
    25321 tatctgaata ataattatcg cgaaaaaatc actttagaac agttatcgaa aaaatttcgt
    25381 gccagcgtca gttatatttg ccatgaattt accaaagagt atcgtatttc ccctattaac
    25441 tatgttattc aacggcgtat gacggaagcg aaatggtcac tcactaatac tgaattatca
    25501 caggcagaga tctcctggcg tgtgggttat gaaaatgtcg atcactttgc caaactgttt
    25561 ttgcgccatg tcggttgttc gcccagcgat taccgcaggc aatttaaaaa ctgttttgcg
    25621 gaacaagaaa tcctatctga atttcctcaa ccggtaagtc ttgccgggta aatctggcgg
    25681 cgcagtttgt taagaagctg cgccgcctgc agattatttg ttctgataat ctttcaggat
    25741 ctgccgaccc gcaacgtaaa tcataatttc gtctgtaccg ccgccgatac gttcacaacg
    25801 gacatcacgc cagaagcggg agacgcgcgc ctcatcggta tagcccagac cgcccatgat
    25861 ttgaatcgca tcatcaatga cttccattgc ggtacgtgca cagtacagtt ttgccagcgc
    25921 cgcgctggtg cgcagtgact gatgctgatc ggcttgccat gccactttca gcaccatgtt
    25981 gcgcatgttg tcgatcttaa tcgccatcag cgccagtttt tcctggatca tctggttatg
    26041 accaatgggc ttaccaaaag cgatacgttg gttggcatag cgggcggcat cttcaaaggc
    26101 gcattcggca aagccggtgc tgcgcgcggc gttgatcagg cgctccatct caaagttgta
    26161 catcacattg aggaaaccca ttccttcttc gcccaccatg tcgctctctt caacctccac
    26221 gttgtcgaga tagacttcgc aggtgctgag catatgccag ccgattttat gcagcgggtt
    26281 aatcttaatg ccgggcttac tggagtcgac ccaccacagg gtgaaggctt ttttgggatc
    26341 tttcggttgc ggatcgcgcg ccagcaccag catatacggg tactctttcg caccggtaat
    26401 aaaggttttt tgtccgttga tgtagacctt gccgttttta cgcgtgtaag tggtagtggc
    26461 actgttgtta tctgagccag cacctggttc cgtcaacgcc agggcatagg cgggatcacc
    26521 cgtttccagg gtgctctctg ccgttttacg tagctgctct gcagaaccga aacggcgcat
    26581 actgtgaata cattgaccgt tggtaattaa aaatgccgga gcaccgcatt ttgacacttc
    26641 catcagcgcc agcatttggg tgacgtaatc cgcagggata ccaccaaatt cttccggcac
    26701 gccaagcatg gaaataccgt tatccgccag cgcccgcata aactcacgcg gatatgtccc
    26761 gttttgatcg caggtgcgga aatactcttc cggaaagtta gtcgtaatca gttcgcgaat
    26821 actggccagc agcagttctt gttcttcagt taaagaaaaa tccatcatta tactcctgtt
    26881 aatgagccgc ttcaggcagg acaaaaccca tcgccgcatc gataaataat ctttcgtcca
    26941 tcagtttgag ttctggcgaa atcactgggg tgaagtccat tttgtcgaga atatcttttt
    27001 gtaaatcgac gccaggggcg atttcgatta aatgcaggcc gtcttctttc agcgtgaata
    27061 cagcacgttc ggtgatgtaa cgaacatcca gtccccgttc gagcgcgatt tttccgctaa
    27121 aagtaatttc cggtagttcc cgaataaatt tatttacccg tccttcctgg acgatatgca
    27181 atttgccatc ggcaatttct gtttttaaac tgcccgcagt taacgtgccg cagaaaataa
    27241 ttttcttcga ggtggcactg atatcaataa atccaccggt acccatgatt ttgccattga
    27301 atttatgcac gccgacgtta ccgtgctggt cgacttcagc aaaactcaaa taacaaacat
    27361 ccagaccacc accgtgataa aaatcaaact gggacgtcat atccagaatg gcgcgggtat
    27421 tcacgttcgc gccaaaggcg ataccctgtg aagtaattcc gccaatcgga cctgtttcta
    27481 ccgtcagaat aaagtcatca gcacaacctt cttcccgggc gaccaggcca ataccgtcag
    27541 caataccgac gccgacattc cccaccgcgc ctttacgcat ttcgaataat gcacgccgcg
    27601 caactaattt acgttggttt aggggcaggc taagtttggt gctgtcatca agggtgaagt
    27661 caccagaaat aaaacggtta accggcgcac cgccatacag ttggctttga tccggatcga
    27721 ccaccacaat atccaccaga taacccggaa tacggacaga tttaggatgc agcgtggctt
    27781 tcttaaccat tttctgcacc tgcatcatca caataccgcc gttattgtgc accgcctggg
    27841 caataaccaa tgcgtcgaga tacatcacct catcttcaaa agtggcgtag ccttcactgt
    27901 cgcaggtggt agcgcgaatg aaggcgatat ctggcgcaat cgctttgtaa tagagatatt
    27961 ctttgttatc aaactcgacc agtttaatca ggtcttcttt cgtgacttca ttcagtttgc
    28021 cgccttgctg gcgtggatcg acaaatgtcc cgatgccaat atcactaata ataccaggct
    28081 ggtgggctgc ggcggcgcgt aaggtttgtg taagtacacc ttgtggatag ttataagcaa
    28141 taattttatt ttgttctgcg agttcagaaa tacgcggcga ttgtccccag tgaccacata
    28201 atgcccattt caccagacct tcttgcgcca gaggactaat accacggtcg gcgcgatcgc
    28261 caagccctgt cggactaata atcgataaat tacgtggcgt ttgagtctgt ttatatttat
    28321 cagcaagagc tgtaattaac gtggtggctt ccagaatacc gccgccagcg cctaacacac
    28381 aaagtgttgc ttcgtcggga atataattca ccgcttcctg tgccgacagg accggcactc
    28441 gtccattaat acgaggtggt tttacaggtt tcattgttaa ttcctgattc agatgtgatt
    28501 ttccctacgc cagatggaga attagcgcac agagactcac gaaatatttt tattaaatac
    28561 ggttaaatat attttttaag ttcggcgggg agggtgttcc cgccgaaata ttattgctta
    28621 tgcctggtgt aaaatagtta ataccgtgcg taaatcattt accgagattt gccctggtgc
    28681 agaggctttt tttaccgcac caaaagttgc cgccgagcca aatacttcac cagccagacg
    28741 agaaattacg ccagtttttg ccatcgacat cgtgatgatt ggacgatcgg catactgctc
    28801 ctgcatctcc agggtcgcgg taagcaacgt cagcacatcg ctggtacttt gcggcatcag
    28861 cgcaatctta ggaatatcgg cgtcgaagga ctgcattttg cgcagacggg caatgatttc
    28921 ttcggcttcc ggcgttttat ggaagtcatg gttggacatg acaactttca catcatgcgc
    28981 gtgggcgtag gcgacggttt ctttaacctg atcatcgccg gtaaataact ccagatcgat
    29041 catatcaacc aggccgctgt cgatggctgc acgattgaga gcgatataag cctcggtgga
    29101 aatcgcctgc tcgccgcctt ctttggcact gcggaaggta aacagcagcg gtttttctgg
    29161 catggtttca cggagaattt ttgccgccgc catgacagac tccacattgg agaggtcggc
    29221 aaagtggtcc acacgccatt ccagaatatc aaagtccgct tcacgatagg cgagagcttc
    29281 ggatttcacg cgggcgatat ctttcgccat cagcgagacg atgattttag gtgcgcccgt
    29341 accaatgacg agatctttta cagttacggt tttcattttt taccctttct gcacgcggtc
    29401 agcctgtcag gcaccgaacc ccatgacctg tttaacatat tccagaggga aatctttgcc
    29461 agtccataac gtgaactgtt cagccccttg ccacaacaac atgccgtatc catcaatcgt
    29521 tttgcaacca gcttgttgcg cctgctgcaa taacttcgtc atatgcgggt tatacacgca
    29581 ttcagtgacc agcagtcccg gatgtaacag actgatatca ttaactaatg attcattctc
    29641 aaggggtttc atacccactt ttgtgccatt ggttaaaatg tcggcggaag ccagggcttc
    29701 agcaaaggct tgctgatcgg cgagatcggt aaccgtgacg acacaatcgg tgttttcgtt
    29761 aacccgctgc gcgaaggcga gggctttatc gaagaactca tcccgacggt taaagagttt
    29821 aatttctttt aaaccttcaa ttgccccctg cgcgccaatc gccgttgagg cacctccggc
    29881 ccctaacagc accattgttt tgcctttgat atcaaaaccg ctctctttaa tggcgcgaat
    29941 atggcccgtg ccgtcggtgt tatagccgcg caggtagcca tcatcattaa cgatggtgtt
    30001 gatggcaccc accagtttgg ctgctggcgt taattcatca acatattcac acgccagttg
    30061 tttgttcggc attgatatac cagttccgcg cattttgagg gcttttaatc cttcaattgc
    30121 tccgggaaaa ctatcgttat ccacttcaaa ggccatatag gtaaatggca atcccgcttt
    30181 ttctaaggct ttattctgca tttcaggcga taaactgtgg cggataggat aggccatcag
    30241 cccaatcaat tcgtattttg cggtaacatc cataattaac tcctttaacc tctatgctta
    30301 attgtgttta accgggtgct aaatttacgc tcgccaaacc gcacatcatt ctcaggaata
    30361 ataaaaacgc ggtaatagcg gataaaaaca ataattgcgg taatcagggc cagcagcgcg
    30421 aaagtaaaat cgagaacaat gatatattga aggccgatgt tcgacagata accggtaatc
    30481 agcggaataa caaagttagc cagtccaccc atcatcatat aaatactggt gactttggct
    30541 ttgctttttg ggaaaaactc tgacatgacc gaaacaccga gctgtaaaat gccgccagct
    30601 gctgagaaac cgataacaaa ggcgccggca ttacacacca gtggagaagg gtacaggtag
    30661 ataatggctg ctgttattgt tgccagtgca gagttaaata cattagccca gatgggccgg
    30721 accatttttt tcagtagtgc ggcaaaaata aagacacaga ccaacgagcc catactgtaa
    30781 taagagatgg tttttaatgc ctcagcttct gacataccag caaaagccat cgcatatttg
    30841 ggcatccaca ccacaatcac ataaaaggtc gagaatgcgg ctacaccgaa cagtaccgat
    30901 gaaacacctt ccagccagac taacggtttg ctgttcattt gcggtaattc attagctacg
    30961 ctggcgtcca ccaactggct ggggaatttg cttttcaaca gcatcagcgt gatcagtaca
    31021 aacagaatac ccggaataat cagcccatag ccgtaccaga tattattgag caacatatag
    31081 ctcaccagca ttgggtagaa catttgccca aatgacacca tcgctttaac cagtatgacc
    31141 gccgaaccag aggctttcgg aaagcattcc atgagcgcgg ggtagccacc cgtatccagc
    31201 gctgagttag cgatacctac gcacactgcc agaccgtagg cgagagttaa attcgggcaa
    31261 gcgggaatac caaagaagaa tagcagatac attattactg ccattaatat caccgcccga
    31321 cgaccaaact tatcggagat cacaccgaag aataaaatac tgatcaatcg ccccaaaccg
    31381 ataccggaaa ttaagtaggc aatgcccgcg ttgtcagtgg aaaacttttc tgccagagat
    31441 gacatatttt gggcaagcgt aataacacta atgccgtgca ggaaatagct gaagtaaata
    31501 caaagaacag ccaggataaa tggcgtgctg aaagccttat tttgagacat tttcacagct
    31561 ccttgctgaa agataatttc gttaccgtac gtattgttct ccgacggttt acataattac
    31621 tatactgaag atgattttcc ctgggtacat ggcataaagt ttatgtttcc aggaatattg
    31681 catgtcatag tttgtttttg atcgcgattt tccttagtta gcgcagaaag agttatttat
    31741 ccgtaagatc ttgcatgacc tgaaaagaat attgcattac ccacccggag cgacattttc
    31801 ctttagcgag tgatgccgcg tttttttgcg gctgcgtaag ccgataaaca gtgccagtaa
    31861 aaaaccgatg gcagcgatgg cggtatcgaa ccacataata tcggcaatac ttctttggga
    31921 cagatgagcc gtaatcaacg gaatagtaaa ggtcgcaata ctgcccgcac tgtaatagat
    31981 ccctgtagct ttacctttag cgtaagggaa acgttcagcc attaacgtca ggccaatttg
    32041 cacaacacct ccagcagagg taaaaccaat gacaaaagca aatattatca ccacataaaa
    32101 tgtgggatgc aggcagacgg taaacagagc aataaatgag aaaaaggtgt acagcatcag
    32161 taatgttgtt gggcgaacgg tattacgaat gagtggagcg gtaataaata cacaaagcag
    32221 cgaacccacg gtgtagatac tgagtagttt aatcgacata gtgtatgaca tgcctgcaac
    32281 aaattgtccg tactgtgcca gccactggct aaccagataa aacgttgcca ttgagatata
    32341 gccatataag gtataactgg ctaaatcgat aattgaacag cgatgttccg tagagctggt
    32401 ggttttcttt atgacaggta agcgacgacc cggatggggt gggaacgtac aacggtataa
    32461 aaacagagcg ttaataaaca taatgcctgc agcaatcata aaggaccaac cgaaccacag
    32521 ttcagcccac actaacaggc taatgattag cggtaataaa aattgtccgc tggaaacaaa
    32581 tgctttaatt aaaatattgg ctgtcccagg tgagcgtgga aaagcttcca tcaaactggg
    32641 ataagtgcct gcatcgagaa aactgtttgc cattcccgcc agaaagccaa aaacataggc
    32701 gataatgatg ttattggtgt gcaggatgcc aaaaaagaag gccatatagc agcacatccc
    32761 gagcatgata aaagggcggc gaccaaagcg atcggataat aatcctgcaa aaagcaagac
    32821 acttaatcga ccaatgccca gcgatgagat aactatcgag acacccgcgg cattagtctg
    32881 ccaaagtgtc tccagcgagg ccatattcag gctcatcaaa atgacgccca taccatgcac
    32941 caggtaatta aaatacaacc caagtgcggt agggtaatag ggatttttca taggttctac
    33001 ttagcaaagg tgctttaaaa agtgtagcga tgttgtgtca gtatccgttc attattgttg
    33061 taacaacgac aattcctttt tgtggagaaa ttaacaaagc cgctccagat cgtgtgcata
    33121 taattcagcg gctaccgatt gatagatctt ccagtcaata aaattgccat cagggtagac
    33181 ttgttgaaac gcggttaagt cggggaaaaa acgcatggtg ttgttgccga tgcggttatt
    33241 tattttctct atgatggcat gaagatgttt ttttcgttgc tgacgcatag ccaacagttg
    33301 ctcgactaca cgatcaggaa tggcgcattt gccattttcc cactgacgcc agctttcact
    33361 gtcaccggtc tgggcaatcc aggtcgcgca ttcatcaata gtcatggcaa aaatatggcg
    33421 aagtgcctgg agttcataag cgttcatcgt gtaatggctg catgaaataa acaataaaat
    33481 ataaataaca ttatcagcct gctgacggct tgaagagagt cacagtatct tgtgcaacat
    33541 tattggaaag agtgaggggc gaggtagcga agcggaaaaa tgttaaaaaa aagcccatcg
    33601 tgggagatgg gcaaagacta cacacagcaa ttcgttgttt cactcagggg atttccatgc
    33661 ttataaatca atatgttgat ttataaccgt aagctaatag taggcatacg gactttttgc
    33721 gtcgatcaga ttcgtctcat tagtttaaaa actgtaaaga atttgcgaca ggtactacca
    33781 gctgaatggc ggtaagcagg aaaatatggg gaagagtaag caaatatcaa ttagcggggg
    33841 ttaacaatca ggcggcagag ccgcctgatg agaaattact tattcggttt ctcgatttcg
    33901 ccaagttctt cgagaatttc ttccggttgg tccgtcggcg gcgggacttc ttccacccac
    33961 gcggcaaaca gacgccagga aacggctaac agaaccggac caataaacag accgatcatc
    34021 ccgaaagcaa tcaaaccacc aataacacca gagaggatca ggatcagcgg taaatcggca
    34081 cccatgcgaa ttaacattgg gcggatgacg ttatccagcg tgccaaccac accgctccac
    34141 actaacaata ccgttcccca ggtggtatcg ccagtccagt agagccagat aatcgccgga
    34201 atcagtaccg gcaacgggcc aagctggaca aggcaggaga ggatcattaa caccgttagc
    34261 aacgttgcat aaggtacgcc ggatacggcg aggccgatac cgccaagcac tgcctgtact
    34321 aacgccgtca ccaccacacc cagcgccacc gcgcggatag cctgtgccgc cagcagtacg
    34381 gcggcatctc cgcgaacgcc tgccagacgg gttgcaaaat ggcgaatgcc ttgtgccacc
    34441 tgttcaccgc gccagtacag cagggcactg aagagaagca tcagcgcaca atgcaccata
    34501 aagcgcccga tatgcgccgc ctgcccaacg aaccaggtgg tggtggtgcc aatataaggg
    34561 cggactttcg ccatgatcgc cgtccccccc atatccagca agttgtgcca gcctgcatac
    34621 agcttcgcgc caatcaccgg aatggtatta agccacgcca gatcgggtaa cgtcatgtcg
    34681 ccgctggaaa tggctttaat tagcgggccg ctgccgtcga cgatactgtt aaccagcaaa
    34741 gcaataggga tgataaacac catcactaat aacagcgtca tcaccagaac ggcgagagag
    34801 cggcggccaa acatgatctt ttgcaaacgt aacaataccg gccaggtggc gataaccacc
    34861 gtaccggccc atgcaaagcc gagaataaag ggttgaacaa tccacagaca tgccacaatc
    34921 atgatggcta aaaacagcac cgaaagcaga atttgtgcga catccctggg ctgacgaaca
    34981 tttaccataa ctacttttca ccttttttgt gcgtcaaatc gtcgacgcga cgtgaacacg
    35041 cgaaactcac ctgcataatg atgagcaatt tcagcggttt ttaacaggcc gattctgccc
    35101 ttaattctga tgggcgtgtt agaaaaaaat gtggtacaac aactcaggca acacgcaaac
    35161 gatttactcg tcgtatttca agttgcatgt gctgcggcta cgttcgttca ccccagtcac
    35221 ttactattgt aagctcctgg agttcactcg cttgccgcct tcctgcaact cgaaatccat
    35281 agagtaaata aacatcacct ttcagtgcgc tattgcagcc gcctgaaaga atagtgtatc
    35341 gacctacatc acagaccgca ggaaagggtc aatataatga ttccacagat ttcccaggca
    35401 cccggcgtcg ttcaactggt gcttaatttt ttgcaagagc tggagcaaca aggttttacc
    35461 ggcgatacgg cgacaagtta tgccgatcgt ctgacaatgt cgaccgacaa cagtatttac
    35521 caacttctcc ccgatgcggt ggtatttccg cgttcaaccg cagatgtggc gctgatcgcc
    35581 cgtcttgccg cgcaggaacg ctattcatcg ctgatcttta ccccccgtgg cggcggcacc
    35641 ggcactaacg gtcaggcgct caaccagggg attattgttg atatgtcccg ccatatgaac
    35701 cgcatcatcg aaattaaccc tgaagagggc tgggtgcgcg ttgaggccgg ggtgataaaa
    35761 gatcaactca atcagtacct gaaaccgttc ggctactttt ttgcgccgga actttcgacc
    35821 agcaaccggg caacgctcgg tgggatgatc aataccgatg cttctggtca gggatcgctg
    35881 gtctatggca aaacgtcgga tcacgtactt ggcgtacgtg cggtgttgtt ggggggcgat
    35941 attctcgata cgcaaccttt acccgtcgaa ttggcggaaa cgctgggtaa atccaatacc
    36001 acaatcgggc gaatttataa cacggtttat caacgttgcc gtcagcaacg ccagttaatc
    36061 atcgacaact tccccaaact taaccgcttt cttaccggtt acgatctgcg tcatgtcttt
    36121 aacgatgaga tgaccgagtt cgacctgacg cgcattctga cgggttcaga agggacgctg
    36181 gcctttatta ccgaagcgcg gctggatatt acgcgcttgc ctaaagtgcg ccgtctggtg
    36241 aatgtcaaat atgactcttt tgactctgcg ctgcgtaacg cgccgtttat ggttgaggcg
    36301 cgggcgcttt cggtagagac ggtggactca aaagtgctga atctggcgcg ggaagatatt
    36361 gtctggcatt ccgtcagcga gttgattacc gatgtgcctg acaaagagat gctcggactg
    36421 aacattgtgg aatttgctgg tgatgatgag gcgctgattg acgagcgagt taatgcactc
    36481 tgtgtgcggc ttgatgagct gattgtcagc caacaggcag gtgtgattgg ctggcaggtg
    36541 tgccgcgagc tggcgggtgt tgaacgtatc tatgcgatgc gcaaaaaagc cgttggtctg
    36601 cttggcaatg ccaaaggtgc cgctaagcca attccgtttg ctgaggatac ctgtgtaccg
    36661 ccggaacatc tggcggatta tattgctgaa tttcgcgcgc tgctcgacag ccacggctta
    36721 agctacggta tgttcggtca cgtcgacgca ggtgttttgc acgtccgtcc agcgctggat
    36781 atgtgcgatc ctcaacaaga gattttgatg aagcaaatct ctgatgacgt ggtggcgctg
    36841 actgcgaaat acggtggttt gttgtggggc gagcacggca aaggttttcg cgctgaatac
    36901 agcccggcgt ttttcggtga ggaacttttt gcagaactgc gcaaagtgaa agcggcattt
    36961 gacccgcata accgactcaa cccagggaag atttgcccgc cagaaggtct cgatgcgccg
    37021 atgatgaaag tggacgcggt gaagcgcggt acattcgatc ggcagatctc cattgcggta
    37081 cgccagcagt ggcgcggtgc gatggagtgt aacggcaacg gtttatgctt caactttgat
    37141 gcccgtagtc cgatgtgtcc gtcgatgaag atcacccaga accggattca ttcaccgaaa
    37201 gggcgcgcaa cgctggtgcg tgaatggctg cgtttgttgg cggatcgcgg cgttgatcca
    37261 ctcaaactgg aacaagaact gcctgaatcc ggcgtcagtt tgcggacgtt aattgcccgc
    37321 acgcgcaata gctggcatgc gaataaaggc gaatatgact tctcacacga agtcaaagag
    37381 gcgatgtcgg gctgtctggc ctgtaaagcg tgttcgaccc agtgccccat caaaattgat
    37441 gtgccggagt ttcgctctcg ttttctgcag ctctatcaca cccgttattt acgcccgctg
    37501 cgcgaccacc tcgtcgctac ggtcgagagc tacgcgccgc tgatggcacg cgcgccgaaa
    37561 acctttaact tcttcattaa ccagccgctg gtgcgcaaac tctcggaaaa acatatcggc
    37621 atggttgatt tgccgctgtt gtcggtcccc tcgctacaac aacaaatggt ggggcatcgc
    37681 tcggcaaaca tgacgctgga acagcttgaa tctctcaatg cagagcagaa agcgcgcaca
    37741 gtgttggtgg tgcaggaccc ctttaccagc tattacgatg cgcaagtggt ggcggatttt
    37801 gtccgtctgg tcgaaaaatt aggtttccag cctgtgttac tgccattttc gccaaatggc
    37861 aaagcccagc atattaaagg ttttcttaat cgttttgcga agacggcgaa aaagacggcg
    37921 gatttcctca accgtatggc gaagctgggt atgccaatgg tgggcgtcga tccggcgctg
    37981 gtactttgtt atcgcgatga atataaactg gcgctgggcg aggaacgtgg cgagtttaac
    38041 gtcttactgg cgaatgaatg gctggcaagc gcacttgagt cacagccagt ggctacagtc
    38101 agcggtgaat catggtattt ctttggtcac tgtaccgaag ttaccgcctt gccgggtgcg
    38161 ccagcacaat gggccgcgat atttgcccgt tttggcgcga aactggaaaa tgtcagcgtg
    38221 ggttgctgcg gcatggcagg gacttacgga catgaagcga aaaaccataa aaattcgctc
    38281 gggatctatg agttatcctg gcatcaggct atgcagcgac tgccgcgtaa ccgctgtctg
    38341 gcgaccggat attcctgccg tagccaggta aaacgggttg aaggcacggg ggtacgccat
    38401 cctgtgcagg ctttactgga gattattaaa tgatatggaa acggaaaatc accctggaag
    38461 cactgaatgc tatgggtgaa ggaaacatgg tggggttcct ggatattcgc tttgaacata
    38521 ttggtgatga cacccttgaa gcgacaatgc cagtagactc gcggacaaag cagcctttcg
    38581 ggttgctgca tggaggagca tccgtggtac tggccgaaag tatcggttcc gttgccggtt
    38641 atttatgtac cgaaggtgag caaaaagtgg ttggtctgga aatcaatgct aaccacgtcc
    38701 gctcggcacg agaagggcgg gtgcgcgggg tatgcaaacc gttgcatctc ggttcgcgtc
    38761 accaggtctg gcagattgaa atcttcgatg agaaagggcg tttgtgctgt tcgtcacgat
    38821 tgacgaccgc cattttgtga cgttgtcacc agaaaagtgt gacgcatatt gcctttggtc
    38881 attatctgca cagtaaacgg tggtatactg tgcaggtctt gtctaaaagc gaggatgcta
    38941 tgtctactca acttgatccc acccagctgg ccattgaatt tttacgccgt gaccagagca
    39001 atctttcacc tgcccaatat ctcaaacgtc tgaaacaact agaacttgaa tttgctgacc
    39061 tgcttactct ctcttctgct gaattaaaag aagaaatcta ctttgcctgg cgtctgggcg
    39121 tgcattgatc ctgacttaat gccgcaagtt cgccaaatcg acctggatta acctccgtcc
    39181 aggttcgatg accttcttaa tactgcttat ctaccgcctg atattgttca aaaataatac
    39241 taatcgcagt ttgtgttaaa acggcgggtt agctttatga gattattctt atcgcccctt
    39301 caagagctaa gccactgaga gtgccggaga taagcgccgg atggggtaga aacccttaag
    39361 cctgtgttgc acagacttaa gggttttctt atttctgaac gctgcacttt tttacctatc
    39421 tcttaaatag tcattttcaa tacaactttt tctttttcat cacagcctta atgctcctta
    39481 gataataacc attatctaac aatgagatac ctaattctta gcgtgcctgt taacccacac
    39541 atcagggtct atgcttatta aaagcaggca aaaagcatgt tttacggtaa agcccctgcg
    39601 tttgcttggt tgaactgata atcattatca ctaacatgct gttatacgct gaaagcgatg
    39661 aagtgaggta aatcgatgga tatgcattca ggaaccttta acccacaaga tttcgcctgg
    39721 caaggcttaa cgctgacacc cgcagcggcg atacacatcc gtgagctggt ggcaaagcag
    39781 ccgggtatgg tcggcgtgcg cttaggcgtg aagcaaacgg gctgcgcggg ctttggctat
    39841 gtgctcgaca gtgttagcga gccggacaaa gacgatctgc tgtttgaaca cgacggcgcg
    39901 aagctgtttg tcccgctgca agcgatgccg tttattgatg gcacggaagt cgatttcgtt
    39961 cgtgaaggac ttaatcagat attcaaattt cacaacccta aagcccagaa tgaatgtggc
    40021 tgtggcgaaa gctttggggt ataggcggta ctatgtctcg taatactgaa gcaactgacg
    40081 atgtcaaaac ctggaccggc ggcccgctga attataaaga aggattcttc acccagttag
    40141 ccaccgatga gctggcaaag gggataaacg aagaggtggt gcgcgcaatt tcggcgaagc
    40201 gtaatgagcc ggagtggatg ctggagtttc gtctaaacgc ctatcgcgca tggctggaga
    40261 tggaagaacc gcactggttg aaagcgcact acgacaagct gaattatcag gattacagct
    40321 actactcagc accatcgtgc ggtaattgtg acgacacttg cgcgtctgaa cctggcgcgg
    40381 tgcagcaaac tggcgcgaac gcctttttaa gtaaagaggt ggaggcggcg tttgagcagt
    40441 tgggcgttcc cgtgcgggaa ggcaaagagg tggcggtgga tgccattttc gactcagttt
    40501 cggttgccac tacttatcgc gaaaaactgg cggagcaggg aattattttc tgttcctttg
    40561 gtgaggcgat ccacgatcac ccggaactgg tgcgtaaata tctcggcacc gtggtgccgg
    40621 ggaatgacaa cttctttgcc gcgcttaatg cggcggtagc ctctgacggt acgtttattt
    40681 atgtgcctaa aggcgtgcgc tgcccgatgg aactttccac ctattttcgc attaacgcgg
    40741 aaaaaaccgg gcagtttgag cgtaccattc tggtggccga cgaagacagc tacgtcagct
    40801 acattgaagg ctgttccgct ccggtgcgtg acagctatca gttacacgcg gcagtggtgg
    40861 aagtcatcat ccataaaaac gccgaggtga aatattccac ggtacaaaac tggttccctg
    40921 gcgataacaa caccggcggt attctcaact tcgtcaccaa gcgtgctttg tgcgaaggcg
    40981 aaaacagcaa aatgtcatgg acgcaatcag aaaccgggtc cgcgattacg tggaaatatc
    41041 ccagctgcat tttgcgcggc gataactcca ttggtgagtt ttactcagtg gcgctgacca
    41101 gcggtcatca gcaagcggat accggcacca agatgatcca catcggtaaa aacaccaaat
    41161 cgaccattat ctcgaaaggg atctctgccg gacatagtca gaacagttat cgcggcttag
    41221 tgaaaatcat gccgacggca accaatgcgc gcaatttcac tcagtgcgac tcaatgctga
    41281 ttggcgctaa ttgtggggcg cataccttcc cgtatgtcga atgtcgcaat aacagcgcac
    41341 aactggagca cgaggcaacg acatcacgta ttggtgaaga tcaactgttt tactgcctgc
    41401 aacgcgggat cagcgaagaa gacgccatct cgatgattgt taacggtttc tgcaaagacg
    41461 tgttctcaga actgccgctg gaatttgccg ttgaagcaca aaaactcctc gccatcagtc
    41521 ttgaacacag cgtcggataa ggaataaaca tgttaagtat taaagattta cacgtcagcg
    41581 tggaaggtaa agctatcctg cgtggattaa gcctcgccgt tcgtcccggc gaagttcacg
    41641 ccattatggg gccaaacggt tcgggcaaaa gtaccttatc ggcaacgctt gccgggcgcg
    41701 aagattatga agtgacgggc ggcacggttg agttcaaagg caaagatttg cttgcactgt
    41761 cgccggaaga tcgtgcaggc gaaggcatct ttatggcctt ccagtatccg gtggagattc
    41821 caggcgtcag taaccagttt ttcctgcaaa cggcacttaa tgcagtgcgc agctatcgcg
    41881 gccaggaaac gctcgaccgc tttgattttc aggatttgat ggaagagaaa atcgctctcc
    41941 tgaagatgcc ggaagattta ttaacccgtt cggtaaacgt tggtttttcc ggcggcgaga
    42001 aaaagcgcaa cgatattttg caaatggcgg tgctggaacc ggagttatgc attcttgatg
    42061 agtcggactc cgggctggat attgacgcat taaaagtggt cgccgatggc gtgaactcgc
    42121 tgcgtgatgg caagcgctca ttcatcattg ttacgcacta ccaacgcatt ctcgactaca
    42181 tcaagcctga ttacgtccat gtgctatatc agggacgaat tgtgaaatcc ggcgatttca
    42241 cgttggtcaa acaactggag gagcagggtt atggctggct taccgaacag cagtaacgcg
    42301 ctgcaacagt ggcatcactt gtttgaagct gaagggacaa aacgctcacc gcaagcacag
    42361 cagcatttac aacaattgct gcgtaccgga ctgccgacac gtaaacatga aaactggaaa
    42421 tatacgccgc tggaagggct gaccaatagc cagtttgtca gcattgcggg agagatatcc
    42481 ccacagcagc gagatgcctt agcgttaacg ttagacgctg tgcggctggt atttgtcgat
    42541 ggacgttacg tgtcagcact gagcgatgcg actgaaggca gcgggtatga agtgagcatt
    42601 aacgacgacc gtcagggggt acccgacgct attcaggcgg aagtgtttct gcatttgacg
    42661 gaaagcctgg cacaaagcgt gacgcatatc gccgtgaagc gcggtcaacg gccggcaaag
    42721 ccatttctgt taatgcatat tacccagggc gtggcaggtg aagaggtcaa cactgcccat
    42781 taccgacatc atctggatct ggcggaaggt gccgaagcaa cggtgatcga acattttgtc
    42841 agccttaatg atgctcgtca cttcaccggc gcacggttca ctatcaatgt cgcagcgaac
    42901 gcccacttgc agcatatcaa gctggcgttt gaaaacccgg tcagtcacca ctttgcccat
    42961 aacgatttgt tgctggctga cgatgccacc gcatttagcc atagtttcct gctgggtggc
    43021 gcagtgttac gacacaacac cagtacgcaa ctcaatggcg aaaacagcac gctgcggatc
    43081 aatagcctgg cgatgccggt gaaaaacgag gtgtgtgata cccgtacctg gctggaacac
    43141 aataaaggtt tttgtaacag ccgacagttg cacaaaacta tcgtcagcga caaaggccgc
    43201 gcggtattta acggtttgat caacgtcgcg cagcacgcca tcaaaacgga tggtcagatg
    43261 accaacaata atctgctgat gggcaaactg gcagaagtgg atacgaaacc gcagctggaa
    43321 atctatgcag atgatgtgaa atgcagccac ggcgcgacgg tggggcgtat tgatgatgaa
    43381 cagatgttct atctgcgctc gcgcgggatc aatcagcagg atgcccagca gatgatcatt
    43441 tacgcctttg ctgccgaact gacggaagca ctgcgtgatg aggggcttaa acagcaggtg
    43501 ctggcccgaa tcggtcaacg actgccagga ggtgcaagat gactttttcc gtcgacaaag
    43561 tgcgggccga ctttccggtg ctttcgcgtg aggtaaacgg tttgccgctg gcttatctcg
    43621 acagcgccgc cagtgcgcag aaaccaagcc aggtgattga ctccgaagcc gagttttatc
    43681 gtcacggcta cgcggcggtg catcgcggta ttcatacctt aagcgcccag gcgaccgaga
    43741 aaatggagaa cgtgcgcaag cgggcatcgc tgtttattaa tgcccgttcg gcggaagagc
    43801 tggtgttcgt ccgcggcacg acggaaggga tcaatctggt cgccaatagt tggggcaaca
    43861 gcaacgtgcg ggcgggcgat aacatcatca tcagtcagat ggagcaccac gctaacattg
    43921 ttccctggca gatgctttgc gcacgcgttg gcgcagagct gcgtgtgatc ccgctcaatc
    43981 ccgacggtac gctgcaactg gagacgctac ctaatctgtt cgatgagaaa actcgcctgc
    44041 tggcaattac tcatgtctcc aacgtgcttg gcacagaaaa tcccctggcg gaaatgatca
    44101 cgcttgcgca tcagcatggc gcaaaagtgc tggtggatgg cgctcaggcg gtgatgcatc
    44161 atccggtgga cgttcaggcg ctggattgcg atttttacgt attctccggg cataaactgt
    44221 atggccccac cggaattggc attctttatg tgaaagaagc cttgttgcag gagatgccgc
    44281 cgtgggaagg gggcggttct atgatcgcca ccgtcagcct gagtgaaggc actacctgga
    44341 ccaaagcacc atggcggttt gaagccggta cacccaatac cgggggcatc attggtcttg
    44401 gcgcggcgct ggagtatgtt tcggcgctgg ggcttaatag catagccgag tatgaacaga
    44461 atctgatgca ctacgcgcta tcacagctgg aatctgtacc ggatctcact ctctatggcc
    44521 cgcggaacag gcttggcgtt attgctttta atcttggtaa acaccacgcc tatgatgttg
    44581 gcagttttct cgataactac ggcattgctg tgcgtaccgg acatcactgc gctatgccat
    44641 taatggccta ttacaacgtc cctgctatgt gtcgggcgtc gctggccatg tataacaccc
    44701 atgaagaagt ggatcgtctg gtgaccggac tgcaacgtat tcaccgtctg ctgggataac
    44761 agggaggcac tatggcttta ttgccggata aagaaaaatt gctgcgtaat tttttacgct
    44821 gcgccaactg ggaagagaaa tatctctaca ttattgagct gggccagcgt ctgccagaat
    44881 tacgcgccga agaccgaagc ccacaaaata gcattcaggg ctgccagagt caggtgtgga
    44941 ttgtcatgcg ccagaatgcg cagggaatta ttgaattgca gggcgacagc gatgcggcga
    45001 ttgtgaaagg gcttattgcg gtcgtcttta ttctctacga tcagatgacg ccgcaggata
    45061 ttgtcaattt cgatgtgcgt ccgtggtttg aaaaaatggc gctcacccaa catctcaccc
    45121 catctcgttc acaaggtctg gaagcgatga ttcgcgcaat tcgcgccaaa gccgctgcac
    45181 ttagctaaac taaagggaca gctttcatcc ggttggctca cattgccgga tggtcaatgt
    45241 ttacactgac ctgcacagga gtgttttggt ttcaggtgaa cataagcgcc atccgacgtt
    45301 tcagcgtgag tctccggcaa atacaggagg tttacaatga aacgcgcgtc tttgcttaca
    45361 ctcacgctta tcggcgcttt tagcgccatc caggctgcct gggcggttga ttatccgcta
    45421 ccaccaaccg gaagccgact ggttgggcaa aatcaaacgt atacggtgca agaaggggat
    45481 aaaaaccttc aggctattgc ccgacgtttt gatactgcgg caatgttgat ccttgaagcc
    45541 aataacacta tcgccccggt gccaaaacct ggtacgacga taactattcc ttcacaactg
    45601 ttattacctg atgcaccgcg tcaggggatt atcgttaacc ttgcagagct gcgcctttat
    45661 tattatccgc cgggagaaaa tattgtgcag gtttatccaa taggtattgg attgcagggg
    45721 ctggaaacgc cggtgatgga aacgcgtgtt gggcagaaaa tccctaaccc aacctggacg
    45781 cctacggcag gcattcgtca gcgttcgctg gagcgtggca ttaaattacc gccagtcgtt
    45841 cctgccggac caaataaccc gctaggacgt tacgcactgc gcctcgcgca tggtaatggc
    45901 gaatacctca ttcatggcac cagtgcgccg gacagcgttg gtttgcgcgt cagttcaggg
    45961 tgtattcgca tgaatgcacc ggatattaaa gccttgttct ccagcgtgcg gacgggaacg
    46021 ccggtgaaag tgatcaacga accggtgaaa tattccgtgg aacctaacgg gatgcgttat
    46081 gttgaagtac atcgaccact atcagcagaa gaacagcaaa acgttcagac aatgccatac
    46141 acactgccag caggctttac gcaatttaaa gacaataagg ctgtagatca gaagttagtc
    46201 gataaagcgt tgtatcgtcg ggcagggtat ccggtttcgg tgagcagtgg agcaactccc
    46261 gcagccagca atgcgccttc agtagagtca gcgcagaatg gtgaaccaga gcaagggaat
    46321 atgttacgcg cgacgcagta gcggtaaacg gcagacaaaa aaaatggcgc acaatgtgcg
    46381 ccatttttca cttcacaggt actattactt gcggtattta gtagccatgt tgtccagacg
    46441 ctggttagca cgagctgcgt catctttagc agcctgaacg tcggaacgca ttgcgttcac
    46501 gtcgttgctc agctggtcaa ctttagcgtt cagagtctga acgtcagaag acagctgatc
    46561 gattttagcg ttgctggagc aacctgccag cagagtagaa cccaggatta ccgcgcccag
    46621 taccagttta gtagctttca ttattaatac cctctagatt gagttaatct ccatgtagcg
    46681 ttacaagtat tacacaaagt tttttatgtt gagaatattt ttttgatggg aaggcactta
    46741 tttttgatcg ttcgctcaaa gaagcatcga acgctgggtt ttagataaaa aaattgagag
    46801 aaaacaggat gcttccatcg gattcatctt agataaagtg agattatata gtgaaatccg
    46861 atttgatttt ttattgcttc tggttatcga ttaaataaaa aaagcgccca tcagggcgct
    46921 tcgatataca aattaattca caaaagcaat attacaggac gtgaacagat gcggtgttag
    46981 tagtgccgct cggtaccagt gcgccagaaa ccatgaccac aacatcacct ttctgagcca
    47041 gaccgctctg caaagctagt tctttaccca gacggtagaa gtcatcagta gaggtgattt
    47101 ctttcaccaa ctgcggcaca acgcctttgc tcagcaccag ctgatgtgca gttttttcgt
    47161 tggtggtcag cgccaggatg gttgcatccg ggaagtattt acgcaccgca cgtgcagatt
    47221 taccgccctg ggtcgcaaca acgatcagcg gagcatccag tttttctgca gtttcaactg
    47281 caccacggca aactgcttca gtgatacgca gtttacggct gtcgttgttg aaatccagac
    47341 ggctggtcat tacacggtca gtacgttcgc aaatggtcgc cataatagaa acagcttcca
    47401 gcggatactt accttttgcg gattcaccag acagcataac tgcgtcagta ccatccagaa
    47461 tggcgttagc aacgtcacct gcttctgcgc gggttggacg tgggtttttg atcatggaat
    47521 ccagcatttg agtcgcagta ataacgactt tacgtgcacg gatacatttt tcgatcatca
    47581 tcttctgagc gaagataact tcttcaaccg ggatttcaac acccaggtcg ccacgcgcaa
    47641 ccatgatacc gtcagacgct tcgaggattt cgtcgaagtt gttgaggcct tcctggtttt
    47701 cgattttgga gatgatgtgg atgttttcgc cgccgtgcgc tttcaggtgc tcacggattt
    47761 cgataacgtc agaacgctta cgaataaagg aagcagcaac aaagtctacg ccttgttcgc
    47821 aaccaaagat caggtcctgt ttgtcttttt cagccagtgc tggcagagca atggaaacgc
    47881 caggcaggtt cacacctttg ttttcgccca ggtcaccgtt gttcagcact ttacagataa
    47941 ctttgttacc ttcaatggcg gtaacttcca taccgatcag accatcgtca accagtacgg
    48001 tgttgccaac agacaggtca gtagtgaaac cttcatacgt taccgcaacc atttcgctgt
    48061 tgccgataac agatttatca gtggtgaaag taaaggtctg accagctttc agagaaacgt
    48121 cgttaccgcc ttccagtttc atggtgcgga tttccggacc tttggtatca agcaggatag
    48181 cggcggtttt accagttttg ctcatcacgt tgcgcagatt ctgaatgcgc tgaccgtgtt
    48241 ctgcatagtc accatgagag aagttcagac gcataacgtt catgccagcg tccagcattt
    48301 tagctaacat ctcttcagat tcggttttcg gtccgatggt gcaaacaatt ttggtctttt
    48361 tcatgacagt cttagtcttt aagttgagaa ggatgggaga aacttgcttt ctgggcgcac
    48421 tgccggaaag cgaatccggt attacgaaag tggtggtgcc tcgctctaag gataggtgac
    48481 atcgaaaaag cgtgcagagg aatgtgtgct tgtgtctcag cccaacgtga gtgcctgttt
    48541 ttgagtcgtt gagttctaca gtccaaagtg ctgaaaccat tcaagagtca attggcgcgc
    48601 attatacgct gaaattaatc caaaaggaaa acaaaaacag cgtttcaaaa aatatacaac
    48661 ttgttagaca ataaattgtt atcaaagatt taacgttcca gggaaaaggt tacgcaaaaa
    48721 cttcactgtt tgcgcaacgt ctggtgccga agttgtcagt gtgaggataa gtgaaagttc
    48781 atccggtgta taaatatatc atcgctcaat tgctacagtt aaaataattt atcgcgttat
    48841 ttgtctgatt ttgtttgatt tttgtttaat tggttagatt gatatatgct gatagttggc
    48901 atgataaata ggtataaaga atgggaaatc ggacaaaaga ggatgaactg taccgagaaa
    48961 tgtgcagagt tgtcggtaaa gttgtgctgg aaatgcgcga tctggggcag gaaccaaagc
    49021 atattgttat cgcaggcgta ttacgtacag cattagccaa taaacgcatt cagcgcagtg
    49081 agctggaaaa gcaggcgatg gaaaccgtca ttaacgcact ggtaaaatga ccattcagga
    49141 tgaggcggta agcttcatcc tgatattctt gcttcagttg cggtccagtt aatcattcta
    49201 aataacaact gctgaaatta tacgaatttc ggtatgtatt ttaatttata gcgataatgt
    49261 tatttttatt ttctgcaatg aacgtcaca
//
LOCUS       DAZUDJ010000033        49138 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.033, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000033 DAZUDJ010000000
VERSION     DAZUDJ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49138
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.033"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            15..547
                     /locus_tag="ACHY1N_002546"
                     /pseudo
     CDS             15..547
                     /locus_tag="ACHY1N_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312389.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
     gene            809..2431
                     /locus_tag="ACHY1N_002547"
     CDS             809..2431
                     /locus_tag="ACHY1N_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
                     /protein_id="HFS4044841.1"
                     /translation="MKIGTVAGTNDSTTTIATNDMVQEHVTNFTKELFGYIANGIGDD
                     ISSIARTMLGEVVEKIDDWQIERFQQSIRDDKISFTIQTNHSEKYSMLSDMRAHILRR
                     DNNYQFIVTINSKNYGCYLDNTDINWCSIVYLLNNMTVNDDANDVAVTESYKPVWDWK
                     ISQFNVSDIKFETMINPQFADRTYFSNCSPVDPTSTRPTYFGDTDGSVGAVLYALFAT
                     GHLRIMAEGENFLSQLLNIEDEVLNVLLRENFNEQLDTNVNTIISILNRRDIVLESLQ
                     PYLVINKDAVTPCTFLGDQTGDRFSNICGDQFIIDLLKRIMSINENVHVLAGNHETNC
                     NGNYMQNFTRMKPLDEDTYAGIKDYPVCFYGPKYKIMANHHGITFDDQRKRYIIGPIT
                     VSSDEMTNALDPVELAAIINKKHHAVINGKKFKNSRAISCRSFNRYFSVSTDYRPKLE
                     ALLACSQMLGINQVVAHNGNGGRECIGETGTVLGLNARDSKHAGRMFSMHNCQINPGA
                     GPEITTPWKSYQHEKNRNGLMPLIRRRTMLQL"
     gene            2621..2734
                     /gene="yhiY"
                     /locus_tag="ACHY1N_002548"
     CDS             2621..2734
                     /gene="yhiY"
                     /locus_tag="ACHY1N_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YhiY"
                     /protein_id="HFS4044842.1"
                     /translation="MMTTLLPVFTKPSPLALNALRAGRICRFLLIPDGRIR"
     gene            2797..3864
                     /gene="yhiI"
                     /locus_tag="ACHY1N_002549"
     CDS             2797..3864
                     /gene="yhiI"
                     /locus_tag="ACHY1N_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFS4044843.1"
                     /translation="MDKSKRHLAWWVVGALAVAAVVAWWLLRPAGVPEGFAVSNGRIE
                     ATEVDIASKIAGRIDTILVKEGQFVREGEVLAKMDTRVLQEQRLEAIAQIKEAQSAVA
                     AAQALLEQRQSETRAAQSLVNQRQAELDSVAKRHMRSRSLAQRGAISAQQLDDDRAAA
                     ESARAALESAKAQVSASKAAIEAARTNIIQAQTRVEAAQATERRIAADIDDSELKAPR
                     DGRVQYRVAEPGEVLAAGGRVLNMVDLSDVYMTFFLPTEQAGTLKLGGEARLILDAAP
                     DLRIPATISFVASVAQFTPKTVETSDERLKLMFRVKARIPPELLQQHLEYVKTGLPGV
                     AWVRVNEELPWPDDLVVRLPQ"
     gene            3861..6596
                     /gene="rbbA"
                     /locus_tag="ACHY1N_002550"
     CDS             3861..6596
                     /gene="rbbA"
                     /locus_tag="ACHY1N_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HFS4044844.1"
                     /translation="MTHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLI
                     GPDGVGKSSLLSLISGARVIEQGNVMVLGGDMRDPRHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDPLSRAQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWL
                     VAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIA
                     IEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAW
                     LFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMS
                     ERFKLNDVEDILPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFI
                     AYLQEAAGQSNEAEAPPVVHDTTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALM
                     GTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDEL
                     DRRMRAGDITVAIEIPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWL
                     QDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVR
                     EKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCGLSVFVFGVPHKGSFLTL
                     TLAALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGR
                     WIGEVYPTSHFLTIARGTFSKALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG"
     gene            6596..7720
                     /gene="yhhJ"
                     /locus_tag="ACHY1N_002551"
     CDS             6596..7720
                     /gene="yhhJ"
                     /locus_tag="ACHY1N_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4044845.1"
                     /translation="MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTP
                     GSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIP
                     PNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVS
                     LETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF
                     EIMMAKIWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIF
                     MGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAI
                     LYRGAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA"
     gene            7793..8068
                     /locus_tag="ACHY1N_002552"
     CDS             7793..8068
                     /locus_tag="ACHY1N_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFS4044846.1"
                     /translation="MRTKVQALRKKQKNTLDQIFKTPVPQGIKWSDIESLVKALGGEI
                     KEGRGSRCKFILNMSVACFHRPHPSPDTDKGAVESVRDWLLSIGVKP"
     gene            8065..8424
                     /locus_tag="ACHY1N_002553"
     CDS             8065..8424
                     /locus_tag="ACHY1N_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFS4044847.1"
                     /translation="MIKLKTPNSMEIAGQPAVITYVPELNAFRGKFLGLSGYCDFVSD
                     SIQGLQKEGELSLLEYLEDCKAAGIEPYARTEKIKTFTLRYPESLSERLNNAAAQQQV
                     SVNTYIIETLNERLNHL"
     gene            complement(8474..9334)
                     /locus_tag="ACHY1N_002554"
     CDS             complement(8474..9334)
                     /locus_tag="ACHY1N_002554"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase"
                     /protein_id="HFS4044848.1"
                     /translation="MPLVNGRILLDRIQEKRVLAGAFNTTNLETTISILNAIERSGLP
                     NFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLHLDHGKTLEDVKQAVRAGFTSVM
                     IDGAAFSFEENIAFTQEAVDFCKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKT
                     FVERTGCDMLAVSIGNVHGLDDIPRIDIPLLKRIAEVCPVPLVIHGGSGIAPEILRSF
                     VNYRVAKVNIASDLRKAFITAVGKAYVNNHNEANLARVMASAKNAVEEDVYSKILMMN
                     EGHRLVRKAS"
     gene            complement(9366..9635)
                     /locus_tag="ACHY1N_002555"
     CDS             complement(9366..9635)
                     /locus_tag="ACHY1N_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HFS4044849.1"
                     /translation="MLNKTVEVRNSTGLHARPAACLAKAAKKYSCKVTLHYEGNDINA
                     TSMMNIMRAGIKGGKTVEIRCDGDDENEAIQTLTDLFRDRFGEAE"
     gene            complement(9625..11133)
                     /locus_tag="ACHY1N_002556"
     CDS             complement(9625..11133)
                     /locus_tag="ACHY1N_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HFS4044850.1"
                     /translation="MPDNSAAIVIDIGTTNCKVTCFSCLDATTLGAHKFVTAKQISPQ
                     GDVDFDIDALWQEVRQAIAQLNAASPLPVRRISIASFGESGVFLDEHGEILTPMLAWY
                     DRRGEEYLATLSEADSAALYDICGLPLHSNYSAFKMRWLLEHYPLRNRRGLRWLHAPE
                     VLLWRLTGEQRTDITLASRTLCLDVRKGEWSAKAAALLHVPCTAFAPLVQPGEHAGWV
                     SESLCKTLGFSQPVSVTLAGHDHMVGARALQMMPGDILNSTGTTEGILQLDTQPTLDE
                     QAKRDKLANGCYSLANQFTLFASLPVGGFALEWLRNTFRLTDEEIAASLTRGHADYLA
                     GNWLLDDIPVFIPHLRGSGSPYKNRHTRGLFYGLGDTLSIDMLIASVSLGLTMEFANC
                     FACFNVPGTSALKVIGPATHNPLWLQLKADILQRPVEAIAFNEAVSVGALLTAAPDIP
                     PPPVAIAQRLLPNRARYHQLQRYQHKWKSWYQLKLQQEGVMPLHHREEHYVE"
     gene            complement(11126..12484)
                     /locus_tag="ACHY1N_002557"
     CDS             complement(11126..12484)
                     /locus_tag="ACHY1N_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HFS4044851.1"
                     /translation="MNDIAHTLYNIVQYILGFGPTVMLPLVLFILALCFKVKPAKALR
                     SSLTVGIGFVGIYAIFDILTSNVGPAAQAMVERTGINLPVVDLGWPPLSAITWGSPIA
                     PFVIPLTILINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSLFFGLLAAAIAA
                     VVVLKLADWSAPLVQKYFGLEGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPE
                     TVQKKFGIFGEPMMVGTILGILLGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEG
                     LLPLSEAIKKYLNAKYPDRDDLYIGLDIAVAVGNPAIISTALLLTPISVFIAFVLPGN
                     EVLPLGDLANLAVMASMIALASRGNIFRTVLAAIPVIIADLWIATKIAPFITGMAKDV
                     NFKFAEGSSGQVSSFLDGGNPFRFWLLEIFNGNIIAIGLVPVIALVLYGIFRITRSTV
                     YA"
     gene            complement(12561..12842)
                     /locus_tag="ACHY1N_002558"
     CDS             complement(12561..12842)
                     /locus_tag="ACHY1N_002558"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4044852.1"
                     /translation="MSQTILFVCATGIATSTAVTEKVMEYCKEHGLNVNYSQTNVASL
                     PGNTDGVALVVSTTKVPYELDVPVVNGLPIITGIGEEKVLAQIVSILKN"
     gene            complement(12839..13312)
                     /locus_tag="ACHY1N_002559"
     CDS             complement(12839..13312)
                     /locus_tag="ACHY1N_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4044853.1"
                     /translation="MQGIHFQENYIQRLPAGLSVEQIIRQLAQPLVAAELVVPDFADH
                     VLKREATYPTGLPTEPPCVAIPHTDHKHVRHNAIAVGILPEPVEFADMGGDPDPVPVR
                     VIFLLALSESNKQLNALGWIMEMIQDTPFMQALLAMETTEIHTVILNKMKERGEI"
     gene            complement(13337..14083)
                     /locus_tag="ACHY1N_002560"
     CDS             complement(13337..14083)
                     /locus_tag="ACHY1N_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4044854.1"
                     /translation="MKSLSKSSQIPLYQQVVEWIRESIYTGDLVEDDRIPSEYQIMDM
                     LEVSRGTVKKAVAQLVKEGVLIQVQGKGTFVKKENVAYPLGEGLLSFAESLESQKIHF
                     TTEVITSRIESANRYVAEKLRITPGQDILYLERLRSIGDEKAMLIENRINIELCPGIA
                     EIDFNQHNLFPTIESLSQRKIRYSESRYAARLIGNERGHFLDISEDAPVLHLEQLVFF
                     SRGLPIEFGNVWLKGNKYYLGTVLQRREVS"
     gene            complement(14282..14683)
                     /gene="nikR"
                     /locus_tag="ACHY1N_002561"
     CDS             complement(14282..14683)
                     /gene="nikR"
                     /locus_tag="ACHY1N_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0010045 - response to nickel cation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HFS4044855.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEA
                     TQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            complement(14689..15495)
                     /gene="nikE"
                     /locus_tag="ACHY1N_002562"
     CDS             complement(14689..15495)
                     /gene="nikE"
                     /locus_tag="ACHY1N_002562"
                     /EC_number="7.2.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015413 - ABC-type nickel transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015675 - nickel cation transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikE"
                     /protein_id="HFS4044856.1"
                     /translation="MTLLNVCGLSHHYAHGGFSGKHQHQAVLNNVSLTLKSGETVALL
                     GRSGCGKSTLARLLVGLESPSQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAV
                     NPRKTVREILREPMRHLLSLKKSEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQRV
                     CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERF
                     CQRVMVMDNGQIVETQVVGDKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV"
     gene            complement(15492..16256)
                     /gene="nikD"
                     /locus_tag="ACHY1N_002563"
     CDS             complement(15492..16256)
                     /gene="nikD"
                     /locus_tag="ACHY1N_002563"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015413 - ABC-type nickel transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0015675 - nickel cation transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikD"
                     /protein_id="HFS4044857.1"
                     /translation="MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSL
                     TCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHA
                     RETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP
                     FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGK
                     IVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS"
     gene            complement(16256..17089)
                     /gene="nikC"
                     /locus_tag="ACHY1N_002564"
     CDS             complement(16256..17089)
                     /gene="nikC"
                     /locus_tag="ACHY1N_002564"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015099 - nickel cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikC"
                     /protein_id="HFS4044858.1"
                     /translation="MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSR
                     LLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLVIGGSAGLIGGR
                     VDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISL
                     RQREFVLASRLSGAGHVRVFVDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVT
                     APTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHA
                     H"
     gene            complement(17086..18030)
                     /gene="nikB"
                     /locus_tag="ACHY1N_002565"
     CDS             complement(17086..18030)
                     /gene="nikB"
                     /locus_tag="ACHY1N_002565"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikB"
                     /protein_id="HFS4044859.1"
                     /translation="MLRYVLRRFLLLIPMVLAASVIIFLMLRLGTGDPALDYLRLSNL
                     PPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGISFASQRPVLDDMLNFLPATL
                     ELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV
                     YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLDVAGQRHVTWARLRGLND
                     KQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPV
                     IQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA"
     gene            complement(18030..19604)
                     /gene="nikA"
                     /locus_tag="ACHY1N_002566"
     CDS             complement(18030..19604)
                     /gene="nikA"
                     /locus_tag="ACHY1N_002566"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015413 - ABC-type nickel transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0015675 - nickel cation transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4044860.1"
                     /translation="MLSTLRRTLFALLACASFIVHAAAPDEITTAWPVNVGPLNPHLY
                     TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFD
                     AEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRP
                     FRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITF
                     NVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALN
                     TAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPRQYDP
                     QKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGAD
                     VSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADK
                     PLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYA
                     PIATEIPFEQIKPVKP"
     gene            complement(19715..20302)
                     /gene="acpT"
                     /locus_tag="ACHY1N_002567"
     CDS             complement(19715..20302)
                     /gene="acpT"
                     /locus_tag="ACHY1N_002567"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HFS4044861.1"
                     /translation="MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHT
                     LSPLPEIIYGEQGKPAFAPETPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRANWR
                     WLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYHSS
                     LSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN"
     gene            complement(20357..21406)
                     /gene="yhhT"
                     /locus_tag="ACHY1N_002568"
     CDS             complement(20357..21406)
                     /gene="yhhT"
                     /locus_tag="ACHY1N_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4044862.1"
                     /translation="METPQPDKTGMHILLKLASLVVILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVQRPIAITIVVVVMLIALTALVGVLAASFNEFISMLPKFNKELT
                     RKLFKLQEMLPFLNLHMSPERMLQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVF
                     MLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELM
                     GVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGIYECILVGALFLVVHMVIG
                     NILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            21538..22755
                     /gene="yhhS"
                     /locus_tag="ACHY1N_002569"
     CDS             21538..22755
                     /gene="yhhS"
                     /locus_tag="ACHY1N_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417930.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4044863.1"
                     /translation="MPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYV
                     HDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADLLGPKKIVVFGLCGCFLSGLGYLT
                     AGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTY
                     GAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLG
                     SVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGIN
                     RIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFPALGVVAVKAVP
                     QQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAIALLLTWRLKK
                     RPPEHVPEAASSS"
     gene            complement(22759..23316)
                     /gene="dcrB"
                     /locus_tag="ACHY1N_002570"
     CDS             complement(22759..23316)
                     /gene="dcrB"
                     /locus_tag="ACHY1N_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417929.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage sensitivity protein DcrB"
                     /protein_id="HFS4044864.1"
                     /translation="MRNLVKYVGIGLLVMGLAACDDKDTNATAQGSVAESNATGNPVN
                     LLDGKLSFSLPADMTDQSGKLGTQANNMHVWSDATGQKAVIVIMGDDPKEDLAVLAKR
                     LEDQQRSRDPQLQVVTNKAIELKGHKMQQLDSIISAKGQTAYSSVILGNVGNQLLTMQ
                     ITLPADDQQKAQTTAENIINTLVIQ"
     gene            complement(23389..24054)
                     /gene="yhhQ"
                     /locus_tag="ACHY1N_002571"
     CDS             complement(23389..24054)
                     /gene="yhhQ"
                     /locus_tag="ACHY1N_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1990397 - queuosine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HFS4044865.1"
                     /translation="MNVFSQTQRYKALFWLSLFHLLVITSSNYLVQLPVSIFGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLISYVISSLFYMGSWQGFGALA
                     HFNLFVARIATASFMAYALGQILDVHVFNRLRQSRRWWLAPTASTLFGNVSDTLAFFF
                     IAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMYGVLLNMLLKRLADKSEINAL
                     QAS"
     gene            24275..24520
                     /gene="tusA"
                     /locus_tag="ACHY1N_002572"
     CDS             24275..24520
                     /gene="tusA"
                     /locus_tag="ACHY1N_002572"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097163 - sulfur carrier activity
                     [Evidence IEA];
                     GO_process: GO:0002143 - tRNA wobble position uridine
                     thiolation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HFS4044866.1"
                     /translation="MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIAD
                     DPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG"
     gene            complement(24622..26820)
                     /gene="zntA"
                     /locus_tag="ACHY1N_002573"
     CDS             complement(24622..26820)
                     /gene="zntA"
                     /locus_tag="ACHY1N_002573"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HFS4044867.1"
                     /translation="MSTPDNHGKKAPQFAAFKPLTTVQNANDCCCDGACSSSPTLSEN
                     VSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVES
                     AVQKAGYSLRDEQAADEPQASRLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATT
                     LVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARQGVSALMALKPETATRLRNGEREEVAINSLRPGDVIEVAAGGRLPADGKLL
                     SPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIE
                     EAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTA
                     IHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEA
                     QVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGIIALQDTLRADAA
                     TAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTKLNQHAPLA
                     MVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANI
                     RQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLRRR"
     gene            complement(26894..27520)
                     /gene="yhhN"
                     /locus_tag="ACHY1N_002574"
     CDS             complement(26894..27520)
                     /gene="yhhN"
                     /locus_tag="ACHY1N_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HFS4044868.1"
                     /translation="MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALS
                     AFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            27661..28020
                     /gene="yhhM"
                     /locus_tag="ACHY1N_002575"
     CDS             27661..28020
                     /gene="yhhM"
                     /locus_tag="ACHY1N_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HFS4044869.1"
                     /translation="MSKPPLFFIVIIGLIVVAASFRFMQQRREKADNDMAPLQQKLVV
                     VSNKREKPINDRRSRQQEVTPAGTSMRYEASFKPQSGGMEQTFRLDAQQYHALTVGDK
                     GTLSYKGTRFVSFVGEQ"
     gene            complement(28023..28292)
                     /gene="yhhL"
                     /locus_tag="ACHY1N_002576"
     CDS             complement(28023..28292)
                     /gene="yhhL"
                     /locus_tag="ACHY1N_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HFS4044870.1"
                     /translation="MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMH
                     GMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLVWQKKFKVKK"
     gene            complement(28282..28878)
                     /gene="rsmD"
                     /locus_tag="ACHY1N_002577"
     CDS             complement(28282..28878)
                     /gene="rsmD"
                     /locus_tag="ACHY1N_002577"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HFS4044871.1"
                     /translation="MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATLIEMDRAVSQQLIKNLATLKAGN
                     ARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADEALIYVESEV
                     ENGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDAD"
     gene            29028..30521
                     /gene="ftsY"
                     /locus_tag="ACHY1N_002578"
     CDS             29028..30521
                     /gene="ftsY"
                     /locus_tag="ACHY1N_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFS4044872.1"
                     /translation="MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEP
                     VKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETP
                     EPVAIEREELPLPEDVNAEEVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELEAQAL
                     AAEAAEEAVMVVPPVEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLF
                     RGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMG
                     EILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRA
                     AAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSH
                     LMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDG
                     TAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            30524..31192
                     /gene="ftsE"
                     /locus_tag="ACHY1N_002579"
     CDS             30524..31192
                     /gene="ftsE"
                     /locus_tag="ACHY1N_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFS4044873.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMQPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDINLISRRSYRMLTLSDGHLHGG
                     VGHE"
     gene            31185..32243
                     /gene="ftsX"
                     /locus_tag="ACHY1N_002580"
     CDS             31185..32243
                     /gene="ftsX"
                     /locus_tag="ACHY1N_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFS4044874.1"
                     /translation="MNKRDAINHIRQFGGRLDRFRKSVGGSGDGGRNAPKRAKSSPKP
                     VNRKTNVFNEQVRYAFHGALQDLKSKPFATFLTVMVIAISLTLPSVCYMVYKNVNQAA
                     TQYYPSPQITVYLQKTLDDDAAAGVVAQLQAEQGVEKVNYLSREDALGEFRNWSGFGG
                     ALDMLEENPLPAVAVVIPKLDFQGTESLNTLRDRITQINGIDEVRMDDSWFARLAALT
                     GLVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDSINVQKLIGATDGFILRPFLYGG
                     ALLGFSGALLSLILSEILVLRLSSAVAEVAQVFGTKFDINGLSFDECLLLLLVCSMIG
                     WVAAWLATVQHLRHFTPE"
     gene            32488..33342
                     /gene="rpoH"
                     /locus_tag="ACHY1N_002581"
     CDS             32488..33342
                     /gene="rpoH"
                     /locus_tag="ACHY1N_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HFS4044875.1"
                     /translation="MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYH
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            33613..34716
                     /gene="livJ"
                     /locus_tag="ACHY1N_002582"
     CDS             33613..34716
                     /gene="livJ"
                     /locus_tag="ACHY1N_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate-binding protein LivJ"
                     /protein_id="HFS4044876.1"
                     /translation="MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQ
                     EFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVAVANKVVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGLDSDQGPTAAKYILEKVK
                     PQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENID
                     FVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYD
                     QVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDPAEIAKYLKANSVDT
                     VMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK"
     gene            complement(34915..35298)
                     /gene="panM"
                     /locus_tag="ACHY1N_002583"
     CDS             complement(34915..35298)
                     /gene="panM"
                     /locus_tag="ACHY1N_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0031638 - zymogen activation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HFS4044877.1"
                     /translation="MKLTIIRLENFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARF
                     NERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPAVSCWWMADAGV
                     EDRGVMTAFMQALGFTAQQGGWEKR"
     gene            35722..36831
                     /gene="livK"
                     /locus_tag="ACHY1N_002584"
     CDS             35722..36831
                     /gene="livK"
                     /locus_tag="ACHY1N_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HFS4044878.1"
                     /translation="MKRNAKTIIAGMIALAISHTAMADDIKVAVVGAMSGPIAQWGDM
                     EFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLDSSQGPTAAKYILETVK
                     PQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENID
                     FVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYD
                     QDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA
                     NTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK"
     gene            36879..37805
                     /gene="livH"
                     /locus_tag="ACHY1N_002585"
     CDS             36879..37805
                     /gene="livH"
                     /locus_tag="ACHY1N_002585"
                     /EC_number="7.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HFS4044879.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMMGIDTGWLLVAAGFVGAIVIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVI
                     WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            37802..39079
                     /gene="livM"
                     /locus_tag="ACHY1N_002586"
     CDS             37802..39079
                     /gene="livM"
                     /locus_tag="ACHY1N_002586"
                     /EC_number="7.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease LivM"
                     /protein_id="HFS4044880.1"
                     /translation="MKPMHIAMALLSAAMFFILAGVFMGVQLELDGTKLVVDTASDVR
                     WQWVFIGTAVVFFFQILRPAFQKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVA
                     WPFMVSRGTVDIATLTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPIAGLMAAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTFFGLEFSRTAREGGWDTFSNFFGLKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPRRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAILLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKNGAAKGEQA"
     gene            39076..39843
                     /gene="livG"
                     /locus_tag="ACHY1N_002587"
     CDS             39076..39843
                     /gene="livG"
                     /locus_tag="ACHY1N_002587"
                     /EC_number="7.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HFS4044881.1"
                     /translation="MSQPLLSVNGLMMRFGGLLAVNNVNLELYPQEIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTILLRDQHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPSFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGTPLANGTPEQIRNNPDVIRAYLGEA"
     gene            39845..40558
                     /gene="livF"
                     /locus_tag="ACHY1N_002588"
     CDS             39845..40558
                     /gene="livF"
                     /locus_tag="ACHY1N_002588"
                     /EC_number="7.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HFS4044882.1"
                     /translation="MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDQFQERIKWVYELFPRLHERRVQRAGTMSGGEQQMLAIGRALMSNPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDALLANEAVRSAYLGG"
     gene            40954..42270
                     /gene="ugpB"
                     /locus_tag="ACHY1N_002589"
     CDS             40954..42270
                     /gene="ugpB"
                     /locus_tag="ACHY1N_002589"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HFS4044883.1"
                     /translation="MKPLHYTASALALGLALMGNAQAVTTIPFWHSMEGELGKEVDSL
                     AQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKNKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADTATRQMLNKPPLPFTKGLRLGN
                     MPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS"
     gene            42368..43255
                     /gene="ugpA"
                     /locus_tag="ACHY1N_002590"
     CDS             42368..43255
                     /gene="ugpA"
                     /locus_tag="ACHY1N_002590"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HFS4044884.1"
                     /translation="MSSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLDNFVTLFHDSYYLDSFWTTIKFSTFVTVSGLLVSLFFAALVEYIVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFL
                     VIVLTVVQFRYVESKVRYQ"
     gene            43252..44097
                     /gene="ugpE"
                     /locus_tag="ACHY1N_002591"
     CDS             43252..44097
                     /gene="ugpE"
                     /locus_tag="ACHY1N_002591"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_process: GO:0015794 - glycerol-3-phosphate
                     transmembrane transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HFS4044885.1"
                     /translation="MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQAVYAA
                     PMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLQMLDSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGL
                     VDSEK"
     gene            44099..45169
                     /gene="ugpC"
                     /locus_tag="ACHY1N_002592"
     CDS             44099..45169
                     /gene="ugpC"
                     /locus_tag="ACHY1N_002592"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol 3-phosphate ABC transporter ATP
                     binding protein UgpC"
                     /protein_id="HFS4044886.1"
                     /translation="MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTEGDIWINDQRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMGKQQIAERVKEAARILELDGLLKCRPRELSGGQRQRVAMGRAIVRDPAVFLFDE
                     PLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGT
                     PVEVYEKPASLFVASFIGSPAMNLLTGRVNTEGTHFELDGGIVLPLNGGYRQYAGRKM
                     TLGIRPEHIALSSQAEGGVPLVMDTLEILGADNLAHGRWGEQKLVVRLAHQERPTAGS
                     TLWLHLAENQLHLFDGETGQRV"
     gene            45166..45909
                     /gene="ugpQ"
                     /locus_tag="ACHY1N_002593"
     CDS             45166..45909
                     /gene="ugpQ"
                     /locus_tag="ACHY1N_002593"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFS4044887.1"
                     /translation="MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAE
                     RCREHGMMANIEIKPTTGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQLAA
                     PELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLDKVRVMQLKDAGLRILVYTVNKP
                     QRAAELLRWGVDCICTDAIDVIGPNFTAQ"
     gene            complement(45896..46336)
                     /gene="yhhA"
                     /locus_tag="ACHY1N_002594"
     CDS             complement(45896..46336)
                     /gene="yhhA"
                     /locus_tag="ACHY1N_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
                     /protein_id="HFS4044888.1"
                     /translation="MKRLLILTALLPFVGFAQPINTLNNPNQPGYQIPSQQRMQTQMQ
                     TQQIQQKGMLNQQLKTQTQLQQQHLENQINNNSQRVLQSQPGERNPARQQMLPNTNGG
                     MLNSNRNPDSSLNQQHMLPERRNGDMLNQPSTPQPDIPLKTIGP"
     gene            46456..48198
                     /gene="ggt"
                     /locus_tag="ACHY1N_002595"
     CDS             46456..48198
                     /gene="ggt"
                     /locus_tag="ACHY1N_002595"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HFS4044889.1"
                     /translation="MIKPTFLRRVAIAALLSGSCFSAAAAPPAPPVSYGVEEDVFHPV
                     RAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIR
                     SKNGNTTAINFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDK
                     YGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKK
                     GDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERT
                     PISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAY
                     ADRSEYLGDPDFVKVPWQALTNKAYAKSIAEQIDINKAKPSSEIRPGKLAPYESNQTT
                     HYSVVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGD
                     ANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGMNVAEA
                     TNAPRFHHQWLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYG
                     ASDPRSVDDLTAGY"
     gene            complement(48236..48520)
                     /gene="yrhB"
                     /locus_tag="ACHY1N_002596"
     CDS             complement(48236..48520)
                     /gene="yrhB"
                     /locus_tag="ACHY1N_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhB family protein"
                     /protein_id="HFS4044890.1"
                     /translation="MITYHDAFAKANHYLDDADLPVVITLHGRFSQGWYFCFEAREFL
                     ETGDEAARLAGNAPFIIDKDSGEIHSLGTAKPLEEYLQDYEIKKATFGLP"
     gene            complement(48720..48875)
                     /gene="yrhD"
                     /locus_tag="ACHY1N_002597"
     CDS             complement(48720..48875)
                     /gene="yrhD"
                     /locus_tag="ACHY1N_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrhD"
                     /protein_id="HFS4044891.1"
                     /translation="MEKLTTELHSLSEMDRRHVVSILAEIANGYDDFNDMLIYLEFYP
                     NHKILIS"
     gene            complement(48970..>49138)
                     /gene="yrhA"
                     /locus_tag="ACHY1N_002598"
     CDS             complement(48970..>49138)
                     /gene="yrhA"
                     /locus_tag="ACHY1N_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000988499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein YrhA"
                     /protein_id="HFS4044892.1"
                     /translation="DLQERLVIGDDSISIFTYDIKSNFFEIRDNIGTENIFSSFSDFS
                     SFLNEIMDSCS"
BASE COUNT        11762 a        12460 c        13330 g        11586 t
ORIGIN      
        1 ctgcatgact agaaaattat aaactctctg ccggtgatac gtataactta attaaaacgc
       61 tcgatgtttg tcattatgac tcagaaagga aagttttaac cagtcatcac ggaataataa
      121 gagatgaaga aaaaaatgtt attgtctcgg tgctttgcag gttccattta atcagatgaa
      181 aaatcctact gatcctgagg aattagccaa tatttttaat aaaaaacata aagaacacat
      241 ggatgatcct ctattccatc taatccgaag caatactttg aaacccacac ctgtatatgc
      301 taattatttt gataacacta ctgatttcag accagcacgt aaacgtatct tcatatatgg
      361 ggagacactc aaaggtgaag accccagcaa atacattaga caaaaatatg ggcatcatgg
      421 ggtcggggta gatcagaatc aacaatttga taatggtatt atggggctaa attccctgaa
      481 ggaagcacgt gataaaaata ataaaataat ttattcctca gggcttagtt gttttcaatc
      541 tcattaaaac tccatgaata cggtggtatg tctttttaat cctgccagta tttcataggt
      601 tttcttaatc gattgtagag gcatgttctg atgacgcctc tacaatcttt agggactttc
      661 tctgctatga gataagaaat ttcatattat gctttaaggc tgaatgattt gtgcaaaata
      721 taattatttt tccatcgaac atgaggtgta tgtcataaga ttaaatgtta actatgcatt
      781 cctcgcggtg aattatatga ggtaaaagat gaaaattgga actgtggcag gcactaacga
      841 cagtacaacg acaatcgcaa caaatgatat ggtgcaagag catgttacta acttcactaa
      901 agaactgttt gggtatattg caaatggtat aggtgatgat atatcaagta ttgccaggac
      961 aatgctcggt gaagttgtgg aaaaaattga tgattggcaa atagaacgtt tccaacaatc
     1021 tattcgagat gacaaaatat catttaccat acaaacgaat cattcagaaa aatatagtat
     1081 gctatcggac atgcgcgctc atattctacg tagggataat aattatcagt ttattgtgac
     1141 aattaatagt aaaaattacg gctgctatct tgataatacc gatattaatt ggtgcagcat
     1201 tgtttattta cttaataata tgacagtaaa tgatgatgct aatgatgttg cagttactga
     1261 gtcgtacaaa cccgtctggg actggaaaat atcgcaattc aatgtatctg atattaaatt
     1321 cgaaacaatg ataaaccccc agttcgctga cagaacctat ttctccaatt gttcacctgt
     1381 tgatcccaca agtaccagac caacctattt tggcgatacc gatggctcag tcggtgcagt
     1441 tttgtacgcg ctttttgcaa cgggacattt gagaatcatg gctgaaggag aaaatttcct
     1501 tagccagttg cttaatatag aagatgaagt tctcaacgta ttgctaaggg agaactttaa
     1561 tgagcaactt gacactaatg ttaatacaat aatcagtatt ctgaacagaa gagatatagt
     1621 tttagaaagt cttcagcctt atttagttat taataaagac gctgtgacgc catgtacgtt
     1681 tcttggcgac caaaccggcg atcgatttag taatatctgt ggcgatcaat ttatcatcga
     1741 tttgttaaaa cgcataatga gtatcaatga aaatgttcat gtattagctg gaaatcatga
     1801 aacgaattgc aatggtaact atatgcagaa cttcacgcgc atgaaaccac ttgatgagga
     1861 tacctacgct gggataaaag attatcctgt atgtttctat ggccccaaat acaaaataat
     1921 ggcaaatcat catgggataa cttttgatga tcagcgaaaa cgttacatta taggaccgat
     1981 aacagtctct agtgatgaaa tgaccaatgc tctcgatccg gtcgaattag cggcaattat
     2041 caataaaaag caccatgctg taattaatgg caaaaagttt aaaaatagcc gggctatctc
     2101 ttgtcgatcc tttaatcgtt atttttctgt ttcgacagat tacagaccta aacttgaagc
     2161 actattagca tgctcacaaa tgttaggtat aaatcaagtt gttgcacata acggtaatgg
     2221 tggaagagaa tgtataggtg aaacggggac agttttaggt cttaacgccc gtgacagtaa
     2281 acatgctgga agaatgttca gcatgcataa ttgccaaatt aaccctggtg cagggcctga
     2341 gataaccact ccctggaagt cttaccagca tgaaaaaaac agaaatggac ttatgccttt
     2401 gattagaagg cgcacaatgt tacagctctg aaccatagac aacatgaata ttaatgttac
     2461 tatctggttg agactgttga taaaacgtaa aaaggaatgc tctgttcctg caactgaaca
     2521 ggcgtgaaac gcgatccaac aggatggata ccgttttgtc agccagtttt atagatcaca
     2581 cttatgagta tgcgtgtttc atttacggcc aggaatgctg atgatgacaa cattactacc
     2641 cgttttcact aagccttccc cgttggcgct caatgctctg cgcgctggtc gtatttgtcg
     2701 tttccttctt atcccggatg gaagaatccg ctgaacgtcg ttcggcggca gttgtaacac
     2761 gcgtcgtttg cttacaggga ttatggcggg ccgattatgg ataagagtaa gcgccatctg
     2821 gcgtggtggg ttgtcggggc actggcggtg gctgccgtcg tggcgtggtg gctgttgcgc
     2881 ccggcgggtg tgccggaagg ctttgctgtc agcaatgggc gcattgaagc gacggaagtg
     2941 gatatcgcca gcaaaattgc cgggcgtatc gacaccattc tggtgaaaga aggccagttt
     3001 gttcgcgaag gtgaagtgct ggcgaagatg gatactcgcg tgttgcagga acagcgactg
     3061 gaagccatcg cgcaaatcaa agaggcacaa agcgccgttg ccgccgcgca ggctttgctg
     3121 gagcaacgac aaagcgaaac tcgcgccgcg cagtcgctgg ttaatcaacg ccaggcagaa
     3181 ctggactccg tagcaaaacg tcatatgcgt tcccgttcac tggcccaacg aggggctatt
     3241 tctgcgcaac agctggatga cgaccgcgcc gccgctgaga gcgcccgagc tgcgctggaa
     3301 tcggcaaaag ctcaggtttc tgcttctaaa gccgctatag aggcggcacg taccaatatc
     3361 attcaggcgc aaacccgcgt cgaagcggca caagccactg aacggcgcat tgccgcagat
     3421 atcgatgaca gcgaactgaa agccccgcgt gatggacgcg tgcagtatcg ggttgccgag
     3481 ccaggggaag tgctggcggc aggcggtcgg gtgctgaata tggtcgatct cagcgacgtc
     3541 tatatgacct tcttcctgcc aaccgaacag gcgggcacgc tgaaactggg tggtgaagcc
     3601 cggctgatcc tcgatgccgc gccagatctg cgtattccgg cgaccatcag ttttgtcgcc
     3661 agtgtcgccc agttcacgcc aaaaaccgtc gaaaccagcg atgaacggct gaaactgatg
     3721 ttccgcgtca aagcgcgtat cccaccggaa ttactccagc agcatctgga atatgtcaaa
     3781 accggtttac cgggcgtagc gtgggtgcgg gtgaatgaag aacttccgtg gcctgacgac
     3841 ctcgtggtga ggttgccgca atgacgcatc tggaactggt tcccgtcccg cctgtcgcgc
     3901 aactggcggg cgtgagccag cattatggaa aaaccgttgc gctgaacaat attactctcg
     3961 atattccggc ccgctgtatg gtcgggctga ttggtccgga tggcgtcggg aagtcgagct
     4021 tattgtcgtt gatttccggt gcccgcgtca ttgagcaggg caatgtgatg gtgctgggcg
     4081 gcgatatgcg cgacccgagg catcgccgcg acgtctgccc gcgcatcgcc tggatgccgc
     4141 aggggctggg caaaaacctc taccacacct tgtcggtgta tgaaaacgtc gattttttcg
     4201 ctcgcctgtt cggtcacgac aaagcggagc gggaagtgcg aattaatgag ctgctgacca
     4261 gcacggggtt agcaccgttt cgcgatcgtc cggcagggaa actctccggc gggatgaagc
     4321 aaaaacttgg gctgtgctgc gcgttaatcc acgacccgga actgttgatc cttgatgagc
     4381 caacaacggg ggttgacccg ctctcccgcg cccagttctg ggatctgatc gacagtattc
     4441 gtcagcggca gagcaatatg agcgtgctgg tcgccaccgc ctatatggaa gaggccgaac
     4501 gcttcgactg gctggtagcg atgaatgccg gagaagtgct ggcaactggc agcgccgaag
     4561 agctacggca gcaaacgcaa agcgctacgc tggaagaagc atttataaat ctgttaccgc
     4621 aagcgcaacg ccaggcgcat caggcggtag tgatcccacc gtatcaacct gaaaacgcag
     4681 agattgccat cgaagcgcgc gatctgacca tgcgttttgg ttccttcgtt gccgttgatc
     4741 acgttaattt ccgcattcca cgcggggaga tttttggatt ccttggttcg aacggctgcg
     4801 gtaaatccac caccatgaaa atgctcaccg gactgctgcc cgccagcgaa ggtgaggcgt
     4861 ggctgttcgg gcaaccggtt gatccaaaag atatcgatac ccgccgtcgg gtgggctata
     4921 tgtcgcaggc gttttcgctc tataacgaac tcaccgtgcg gcaaaacctt gagttacatg
     4981 cccgtttgtt tcacatcccg gaagcggaaa ttcccgcaag agtggctgaa atgagcgagc
     5041 gttttaagct caacgacgtt gaagatattc tgccggagtc attgccgctc ggcattcgcc
     5101 agcggctttc gctggcggtg gcggtgattc atcgcccgga gatgttaatc ctcgatgagc
     5161 ctacttctgg tgtcgatccg gtggcgaggg atatgttctg gcagttgatg gtcgatctct
     5221 cgcgccagga caaagtgact atcttcatct ccacccactt catgaacgaa gcggaacgtt
     5281 gcgaccgcat ctcactgatg cacgccggaa aagtgcttgc cagcggtaca ccgcaggaac
     5341 tggttgagaa acgcggagcc gccagtctgg aagaggcatt tatcgcctat ttgcaggaag
     5401 cggcagggca gagcaacgaa gccgaagcgc cgcccgtggt acacgacacc acccacgcgc
     5461 cgcgtcaggg atttagcctg cgccgtctgt ttagctacag ccgccgcgaa gcgctggaac
     5521 tgcgacgcga tccagtacgt tcgacgctgg cgctgatggg aacggtgatc ctgatgctga
     5581 taatgggtta cggcatcagt atggatgtgg aaaacctgcg ctttgctgtg ctcgaccgcg
     5641 accagaccgt cagtagccag gcgtggacgc tcaatctctc cggttcccgt tactttatcg
     5701 aacagccgcc gctcaccagt tatgacgagc ttgatcgtcg gatgcgtgcg ggcgatatca
     5761 cggtggcgat tgagatcccg cccaatttcg ggcgcgatat cgcgcgtggt acgcctgtgg
     5821 aactcggcgt ctggatcgac ggagcgatgc ccagtcgtgc cgaaacggta aaaggttacg
     5881 tgcaggcaat gcaccagagt tggcttcagg atgtggcgag ccgacaatcg acacccgcca
     5941 gccaaagcgg gctgatgaac attgagacgc gttatcgcta taacccggac gtaaaaagcc
     6001 tgccagcgat tgttccggcg gtgatcccgc ttctgctgat gatgatcccg tcaatgctaa
     6061 gcgcccttag cgtggtgcgg gaaaaagagc tagggtcgat tatcaacctt tacgtgaccc
     6121 ccaccacccg tagcgaattt ttgcttggca aacagctgcc gtacatcgcg ctggggatgc
     6181 tgaacttttt cctgctctgc ggcctgtcgg tgtttgtgtt tggcgtaccg cataaaggca
     6241 gtttcctgac gctcaccctg gcggcgctgc tgtatatcat cattgccacc ggaatggggc
     6301 tgctgatctc cacctttatg aaaagccaga ttgccgccat tttcggaacg gcgattatca
     6361 cattgatccc ggcgacacag ttttccggga tgatcgatcc ggtagcttcg ctggaagggc
     6421 ctggacgttg gatcggcgag gtttacccga ccagtcattt tctgactatc gcccgcggga
     6481 cgttctcgaa ggcgctggat ctgactgatt tgtggcaact ttttatcccg ttgctgatag
     6541 ccatcccgct ggtgatgggc ttaagtatcc tgctgctgaa aaaacaggag ggatgatgcg
     6601 ccatttacgc aatattttta atctgggtat caaagagttg cgcagtctgc tcggtgataa
     6661 agcgatgctg acgctgattg tcttctcgtt tacggtgtcg gtgtattcgt cagcgaccgt
     6721 tacgcctgga tcgttgaacc tcgcgccgat cgccattgcc gatatggatc aatcgcagtt
     6781 atcgaaccgg atcgttaaca gcttctatcg cccgtggttt ttgccaccgg agatgatcac
     6841 cgccgatgag atggatgccg gactggacgc cggacgctat accttcgcga taaatattcc
     6901 gcctaatttt cagcgtgatg tcctcgccgg acgccagccg gatattcagg tgaacgtcga
     6961 tgccacgcgc atgagccagg catttaccgg caatgggtat atccagaata ttatcaacgg
     7021 tgaagtgaac agctttgtcg cgcgctaccg tgataacagc gaaccgttgg tatcgctgga
     7081 aacccggatg cgctttaacc cgaaccttga tcccgcgtgg tttggcgggg tgatggcgat
     7141 catcaacaac attaccatgc tggcgattgt attgaccgga tcggcgctga tccgcgagcg
     7201 tgaacacggc acggtggaac atttactggt gatgccgata acgccgtttg agatcatgat
     7261 ggcgaagatc tggtcgatgg ggctggtggt gctggtggta tcgggattat cgctggtgct
     7321 gatggtgaaa ggtgtactgg gcgtaccgat tgaaggctcg atcccgctgt ttatgctggg
     7381 cgtggcgctc agtctgtttg ccaccacgtc aatcggcatt tttatgggga cgatagcgcg
     7441 ttcaatgccg caactggggc tgctggtgat tctggtgctg ctaccgttgc aaatgctttc
     7501 tggtggatcc acgccgcgcg aaagtatgcc gcagatggtg caggacatta tgctgaccat
     7561 gccgacgaca cactttgtta gcctcgcgca ggccatcctc taccggggtg ccggattcga
     7621 aatcgtctgg ccgcagttcc tgacgctgat ggcaattggc ggcgcgtttt tcaccatcgc
     7681 actgctgcga ttcaggaaga cgattgggac aatggcgtaa ggaagggaaa cttgacttca
     7741 tactgtgatg tcatactatt gatgtcataa agtgaagtca taaggacatg ccatgagaac
     7801 caaggtacag gctttacgga agaaacaaaa aaatacattg gatcaaatat ttaaaactcc
     7861 tgttcctcaa gggatcaagt ggtctgatat agagtcactg gttaaagcat taggcggaga
     7921 aattaaggaa ggaagaggtt cgcgttgtaa gttcatacta aatatgagcg ttgcgtgttt
     7981 ccatcggcct catccgtcgc cagataccga taaaggcgct gtagaaagcg tgcgtgactg
     8041 gttactaagt ataggggtaa aaccatgatc aaactgaaga cgccaaactc tatggagatt
     8101 gccgggcaac ctgcagttat cacttacgtg ccagaactga atgcatttcg tggcaaattc
     8161 ctgggcttgt caggttattg tgattttgtc tctgacagca ttcaggggct gcaaaaagaa
     8221 ggggaacttt ccctgctaga gtatcttgag gattgtaaag ctgcgggtat tgagccgtat
     8281 gcgcgtacag aaaagattaa gacctttacg ttacgctatc cagaatcgct gagtgaacgc
     8341 cttaataatg cggctgcgca gcaacaagtc tctgttaata cctatattat tgaaacactg
     8401 aatgagcgtt tgaatcattt ataacttata gcggcccaac aatttctgtt gcgccgctat
     8461 atttttgtgg ctcttaagat gcctttctaa ccaaccgatg cccctcattc atcatcagga
     8521 ttttgctata cacatcttcc tcgacggcgt tttttgctga tgccatgact cgtgccagat
     8581 tcgcctcgtt gtgattattc acatacgctt tgccgacggc ggtgataaac gctttgcgca
     8641 gatcgctggc gatatttact ttagcgacgc gataattaac aaagctgcgt aatatctccg
     8701 gggcgatacc ggagccgccg tgaataacca acggcaccgg acagacttcg gcaatgcgct
     8761 tcagcagggg gatatcgata cgcggtatat cgtccaggcc atgaacgttg ccaatagaaa
     8821 ctgccagcat gtcgcaaccg gtacgctcga caaaggtctt caccttttcc ggttccgttt
     8881 tgcaatcggc ttcgctgaca tgatcatctt ctttgccgag aatcgccccc agctccgctt
     8941 caaccggtac accataggat ttacagaaat cgacagcttc ctgggtgaaa gcgatattct
     9001 cttcaaaaga gaatgcggca ccgtcaatca tgaccgaggt aaagcccgcg cgcaccgcct
     9061 gtttcacatc ctccagagtt ttcccgtgat ccagatgaag actgaccgga acatccattt
     9121 tatcggcgtg acgtttcacg atttcataaa tgtaatcgta tcccgagagt tgtgcattgg
     9181 ttggcgcaat ctgaatgaag ttgggtaatc ccgaacgctc aatagcgttt aaaattgaaa
     9241 ttgtcgtctc cagattggtg gtattaaatg cgcccgctaa tacccgtttt tcctgaatgc
     9301 ggtcgagcag tatccgtcca ttaactaatg gcatattgaa aacctcatct tttaatatca
     9361 gttaattatt cagcttcacc gaagcggtcg cgaaataagt cggtgagagt ctgtatggcc
     9421 tcgttttcat catcaccgtc gcagcgtatt tccaccgttt ttccgccttt tattccggcg
     9481 cgcataatat tcatcatgct ggtggcatta atatcattac cctcatagtg cagcgtcact
     9541 ttacagctat attttttggc ggctttcgcc agacaggccg ccggacgtgc atgcaggcca
     9601 gtactgtttc tgacctccac ggttttattc aacatagtgt tcctcccgat gatgtaatgg
     9661 catcacgcct tcttgttgta atttcaactg ataccagctt ttccatttgt gctgataacg
     9721 ctgtaattga tggtatctcg cccgattcgg taacaaacgt tgggctatag cgactggcgg
     9781 cggtggaata tccggtgcgg cggttaataa tgctccgaca gaaaccgcct cgttaaatgc
     9841 aattgcttca accggacgct gtaaaatatc cgcctttaat tgcagccaaa gaggattatg
     9901 ggttgccgga ccgatcactt ttaacgcgct ggtgccaggc acgttaaaac aggcgaagca
     9961 gttggcaaat tccatggtta atcccagtga tacgctggca attaacatgt cgatacttaa
    10021 cgtatcgcca agcccataaa ataatccacg ggtatggcga tttttatagg gcgaacccga
    10081 accgcgaaga tgtggaataa agacgggaat gtcatcgagc aaccaattcc ccgccagata
    10141 atcagcatgt ccgcgagtaa gtgatgcggc gatctcctca tcggttagcc ggaacgtgtt
    10201 gcgcagccac tccagcgcga aaccgcccac gggcagcgac gcaaacaggg tgaactggtt
    10261 ggcaagtgag taacagccgt ttgccagctt gtcacgtttg gcctgttcat ccagcgtcgg
    10321 ttgtgtatcc agttgcagaa tgccttccgt ggtccccgtc gagttaagga tatcgcctgg
    10381 catcatctgc aacgctcgcg cacccaccat atggtcatgt ccggccagcg tcacgctgac
    10441 cggttgcgag aacccaagcg tcttgcaaag tgactcgctg acccatccgg cgtgctcgcc
    10501 tggctgcacc aatggcgcaa atgccgtaca gggaacgtgt aacaacgccg ccgctttcgc
    10561 tgaccattcg cctttgcgca cgtccagaca cagcgtgcgg ctggctaagg tgatatccgt
    10621 gcgctgttcg ccagtcagcc gccagagcag cacttccggc gcatgtagcc agcgcaggcc
    10681 gcggcgatta cgcagcgggt aatgttccag caaccagcgc attttgaagg cagagtaatt
    10741 gctgtgtagt ggtagaccgc agatgtcata aagtgctgca ctgtctgcct cgctaagcgt
    10801 tgccagatac tcttcaccgc gacggtcata ccatgccagc attggcgtca ggatctcgcc
    10861 atgctcgtca aggaacacgc ctgattcgcc aaaactggca atgctgatcc gtctgactgg
    10921 cagcggcgaa gcggcgttca gttgcgctat cgcctggcgg acctcctgcc agagggcgtc
    10981 gatatcgaaa tcgacatcgc cctgtgggga gatctgcttt gccgtcacga atttatgcgc
    11041 gcccaacgtc gttgcgtcca ggcaggaaaa gcaggtgact ttgcaattgg tggtgccaat
    11101 atcgataacg atagctgcgc tgttatcagg cataaaccgt gctccgcgtt attcggaaaa
    11161 tgccatacag taccagggcg ataaccggca ccagaccaat ggcgatgata ttgccgttga
    11221 agatttccag cagccagaag cggaacgggt taccgccatc aaggaaactg gaaacctggc
    11281 cgctggagcc ttcggcaaat ttgaagttaa cgtctttcgc catgccggta ataaacggtg
    11341 cgattttagt cgcaatccac aggtcggcaa taatcaccgg gatcgccgcc agaacggtgc
    11401 ggaaaatatt gccacggctg gctaaagcaa tcatcgacgc cattaccgcc aggttggcaa
    11461 ggtcgccaag cggcaggact tcattacccg gaaggacaaa cgcgataaag accgagatag
    11521 gcgtcagcag cagggcggtg gagataatcg ccgggttacc tacggcaacg gcgatatcca
    11581 ggccgatata gagatcgtca cggtcagggt atttggcatt gagatacttt ttaatggctt
    11641 cagacagcgg taataaacct tccatcagga tgcgtaccat gcgtggcagg atgaacatca
    11701 caccgccaat gctgatgcca agcagcaaca cttttttgaa atcgtatcct gcaatcacgc
    11761 cgagcagtat gcccagaata gtgccaacca tcatcggttc gccgaagatg ccaaactttt
    11821 tctgtacggt ttccgggtcg atatgaatac gattgaggcc ggggatatgg tcgatgattt
    11881 tgtcgaccag cagaccgacc gggaagaaca ccaccgaaga gagcgtcggc aatgagatcc
    11941 cttccagtcc aaagtatttt tgtaccagtg gcgcagacca gtcggcgagt ttaagtacta
    12001 ccaccgcagc aatcgccgcc gccagcaaac caaagaacag gctgccggtg ctgtaataaa
    12061 ccaacgtacc agcaagggca aaatgccagt agttccacat atctacgtca acggtacggg
    12121 ttttatttaa cgccagcatc gccacgttaa tcagaatggt cagggggata acaaacgggg
    12181 caattggcga accccatgta atagcggaaa gcggcggcca gcctaaatct accaccggta
    12241 aattaattcc ggtgcgttca accatcgcct gggccgctgg cccgacattg ctggtcagaa
    12301 tatcgaaaat ggcataaata ccgacaaaac caatgccgac tgttaatgac gaacgtaagg
    12361 ctttagcggg ttttacttta aaacagagag caagaataaa taacaccaac ggcaacatta
    12421 ccgtcgggcc aaatcccaat atatattgca caatattata gagggtatgc gcgatatcgt
    12481 tcataataaa cctctttttc aggcgagagc gcacctcgcg ttagcgcctg atggagtggg
    12541 ttgaaattaa ttattattaa ttaattttta aggatcgaaa caatttgcgc cagtactttc
    12601 tcttcgccaa taccggtaat aatcggcaag ccgttaacta ccgggacgtc gagttcataa
    12661 ggcactttag tcgttgagac taccagtgct acgccatcag tatttccagg taaagaggca
    12721 acgttggttt gggaataatt gacgttaaga ccgtgctctt tacaatattc catgactttt
    12781 tctgttaccg ccgtggatgt ggcaataccc gtggcgcaga caaataaaat ggtttgactc
    12841 atatttcacc tcgttctttc attttgttta agattactgt gtgtatttct gttgtttcca
    12901 tcgcaagcag ggcttgcata aagggcgtat cctgaatcat ttccataatc cagcccaggg
    12961 catttaattg tttattactt tcgcttaagg cgagcaaaaa aatcaccctg acaggtacgg
    13021 ggtcaggatc gccgcccata tcggcaaact ctaccggttc cggcaggatg ccgacggcaa
    13081 ttgcattgtg cctgacatgt ttatggtccg tgtgcggaat agcgacgcac ggtggttcgg
    13141 taggcagccc cgttgggtac gtcgcctcac gtttcagtac gtgatcggca aaatcaggga
    13201 cgaccagctc ggcggcaacc aacggttgcg ctaactgacg gatgatctgt tcaacgctta
    13261 accctgccgg aagtcgttga atataatttt cctgaaaatg tatgccttgc attttactcc
    13321 tcttaaaaaa gtgtacttaa ctcacttccc gccgttgcag tacggtgcca agataatatt
    13381 tatttccttt taaccagacg ttgccaaact caatgggtaa tcctcgggag aaaaagacta
    13441 actgctccag atgcaaaacg ggtgcgtctt cactgatatc taaaaaatga ccacgttcat
    13501 taccaattaa tcgcgcggca tagcgacttt ccgagtaacg aatttttctt tgcgacaaac
    13561 tttctattgt tggaaataaa ttgtgttgat taaaatcgat ttccgcaata ccggggcata
    13621 gctcaatatt gatacggttc tctatcagca tcgctttttc atcaccaatt gagcgtaagc
    13681 gttcaaggta aagaatatcc tgaccgggcg ttattcttaa tttctctgcc acataacgat
    13741 tagccgattc aatccgtgac gtaataactt cagtggtaaa atgtattttc tggctttcca
    13801 gcgattccgc gaatgacaat aatccttcac ctaacggata tgccacgttc tcttttttga
    13861 caaatgttcc cttaccctgg acctgtatta acacgccttc ttttaccagt tgggcgaccg
    13921 cttttttaac ggttccccga ctcacttcca gcatatccat aatctggtat tccgaaggaa
    13981 tgcgatcgtc ttccaccaga tctccggtat aaatactttc tcttatccac tccaccactt
    14041 gttgatagag cggtatttgt gacgacttac ttaatgattt catggcgcgc acctgaacat
    14101 ttacagttgt ctatggacaa tcatggacaa cttcaagcgt atagtaggtg aacgggagaa
    14161 aaagaggatc gaagcgtctc acattttgag ggaccaaatc gtgatcaaaa aaatgtgacg
    14221 tgagtcgata tttgtcagaa gtttactgcg ccgtaaggaa ataacggcgc gttggtcggt
    14281 gttaatcttc cttcggcaag cactgcaaat gcccgtgccg cacgccgcgc tgggcgataa
    14341 cgtcatcggc aaaatgctgc acgtcaccca tgtcaccttt caacacggcg atttccagac
    14401 agtcgtcgtg gttgatgtgc acatgcagcg tggcgacgga gaggtcgtgg tgatgatgct
    14461 gggtggaaac aatacggctg gctaagtcgc gtttttcgtg ttcatacaca tacgacagca
    14521 ccgcgaaacc ttgtgtgccg tgctgctggg tagcttcttg cgccagggcg ctacgcagaa
    14581 tatcgcggat agcttcggaa cggttgttat aaccacgacg ctggctcagg ctgtccagcg
    14641 tctccagtaa atcgtcatca agcgtgatgg tgactcgttg catttgcgtt aaaccttttc
    14701 tgtggtgcga cggcgcacgg ggaatgcggg taataccgcg ttttgtagca cacgtccggc
    14761 gtcagaggaa aaggttaatt tatctcccac cacctgggtt tcgacgattt gtccgttgtc
    14821 catcaccatc acccgctgac agaagcgttc caccaggcgt aagtcgtggg tgatgaacag
    14881 gcaggcggtg ccaaactgtt gttgtagctt tttcagcagg cgaatgacgc ccgcctgtaa
    14941 cacgagatca aggttagaaa cggcttcatc cagaatcagt agtttcggtt cgaccgccag
    15001 cgcgcgagcc aggcagacgc gctggagctg gccgccgctt aactgcggtg ggcgtttgtc
    15061 gagaacgctg tcatcgagat cgaccgcctt cagcatttcg ctggcgcgcg ccagttgttc
    15121 ggattttttc agtgatagca ggtggcgcat cggttcacgc aggatctcgc gcacggtttt
    15181 gcgcggattc acggcgctga tggagtcctg aaataccatc tgaatatcgc ggcggaacgc
    15241 tttacgctgg gcgcgattga gtttcgccag cggttcgccg cgccagctaa tattcccttg
    15301 tgagggagac tctaagccta ccagcagccg cgcgagggtg ctttttccgc agccgctgcg
    15361 tcccagcagg gcgacggttt cgccgctttt cagggtcagg gaaacgttat tcagcaccgc
    15421 ctgatgttga tgttttccgc taaatccacc gtgggcatag tgatgggaaa ggccgcagac
    15481 gttaagtaag gtcatgatgc cagctccata ccgtagaggg cgagatgagc ggaaaccagg
    15541 ctgcgcgtca ccgtatgttt gggggcgtta aacagcgttt ctacatcgcc ctgttcgaca
    15601 attttacctt gtgacatcac cgccacgtca tccgccagac gcgccacaac gcccatatca
    15661 tgggtgacca gcagcattcc cggcgcttgt ttttgcataa tgctttccag cagatcgagg
    15721 atgcgcgcct gtgctaccac gtcgaggtcg gtggtcggtt catcggcgat gataaacggt
    15781 gattcacaca gcaccgccat cgcaatcatc atgcgctgca acatgccgcc gctcatctcg
    15841 aacgggtaca gcttcagcac gcgcgcggcg ttttccagcc ccaccgcttc tatggcagcg
    15901 gtaagcgtag cgtcatcggc gggtttccct aacgccaggc aggtttcccg cgcgtgggtg
    15961 tgcatggtgt gcagtggatt aaaggcgctg cgcgggttct gcatgatggt ggcaattttg
    16021 atgccgcgca gggcgcaagg cgaaaccggt ttgccatcgg ctaaaatttc ccccgccgtc
    16081 tggcgaacgc cagcgggcaa aatgcccagc gtcgcggcgc aggttaatga tttcccgctg
    16141 ccgctaccgc cgactaacgc cagcacgcgc ccgcgttgca gggttaacga tacaccgtgt
    16201 accagcggct gcgcggcctg tagcgcgata ttacgtagtt caatctgttg cggcattagt
    16261 gtgcgtgctc cgtcaccaga tgagggtcca gatgatcgcg cagtgcgtca cccaccaggt
    16321 taaaggccat cacgctgata aacagcgcca gccccggcca gaacatttgc agcggctggg
    16381 tccagatata ctggcgcgcg tcgttaatca tcacgcccca ttcggcggtc ggcgcggtca
    16441 caccgaggcc aaggaaagac atccccgcga cgtgcagcat catatggccg atatccagcg
    16501 ttgccagcac cagcagcgaa gggatcaccg cgcctgccag atgatcgaca aacacccgca
    16561 catggcccgc gccagaaagc cgtgacgcca gcacaaactc gcgttggcgt agtgaaatca
    16621 ccaggctgcg caccatgcgt gcataccacg cccagtgcga cagggcgatg gcgataatta
    16681 cgttggtcag cccggtgccg agcacgccaa ccataaagaa cgacagaatc gaggtcggga
    16741 aggtcataaa catatcggcg acgcgcatgg tggcctgatc aacgcgcccg ccaatcaacc
    16801 cggcgctgcc gccaataacc agccctaatg tcagcaccag cagcaggcag gccattaccg
    16861 aaccgagcga cacgcgggtc gctgccatca gccgcgagaa aatatcgcga cctaagtgat
    16921 cggtgcccag ccagtgctgc gcatccggcg aaagcaggcg cgacggcaaa tcaatcgcct
    16981 gggggtcata cggcagccac cactggctgg tgagcgcaat cagcgccagc agggcgataa
    17041 tgatcagcgc caggcgtacc gaccagcggg aagagaggaa aaagttcacg cgtgcgctcc
    17101 ttcatgacga cgaatgcgcg ggtccagcgc ggcgttgagc aaatcgacaa tcaaattaca
    17161 gaccacaaaa accaccacca tcatcagcgt aaagcactgg atcaccggat agtcacggtt
    17221 aaaaatcgcc gacaccgcat agcgcccgac gcccggccag gcaaagatgt tttcgataat
    17281 catcgtcccg ccaatcagtt cgccgatgtg catccccacg gcggtgatca tcggcagcga
    17341 ggcattgcgc aggatgtggc gacgttcggt ctgtttgtcg ttcaggccgc gcagacgcgc
    17401 ccaggtgacg tgacgctgac cggcgacgtc cagcatactg gcgcgcagta aacgcgcgtt
    17461 aatcgccagc gacataaagg caatggaaac cgcaggcaaa atgatgtgct gccagccgcc
    17521 gtaacccatc gcgggtagcc attgcagata caccgaaaac gccatcacca gtaaaaacgc
    17581 cagccagaag ttaggcatcg acacgccaag aaacgcgatg aaacgtacgg cgaaatccgg
    17641 cagacggtcg cgatggcgcg ccgcccagat accgagcggt acggaagtga gcagaattaa
    17701 taccagcgcc gcacctgcaa gttccagcgt ggcgggcagg aagttcagca tatcgtccag
    17761 caccgggcgt tggctggcga atgagatacc aaagtcaaga tgcagcgcct tccacaacca
    17821 ggtgccgtac tggacgtaca gcggctgatc cagcccgagc atggtgcggg tagaggccag
    17881 catctccggc gtcggcggca ggttagataa acgcagataa tcgagcgccg ggtcgccggt
    17941 accgaggcgc agcatcagaa aaatgatcac cgaggcggcg agcaccatcg ggatcagcag
    18001 cagaaagcgg cgtaatacgt aacgcaacat taaggtttca ccggtttaat ctgttcgaac
    18061 ggaatttcag tggcgatcgg cgcgtagggg atgttaccca gctccggttt tgataccacc
    18121 atcattgaga tgtaactgat aggcagataa accgcctcgt catgcagacg ggtcagaatg
    18181 tcgcgataca gcgcctgacg ttgcgtttcg tcatgggtcg ccagcacttc gccgatctct
    18241 ttatcaatca gcggtttgtc ggctaatcct tgctgtgcct ggaagtcagc gtgtgacggt
    18301 acgcgcattg aactgaggaa ggcgtgtgga tcgtatggcg cgccccaggt gcggtggaaa
    18361 atcatgccaa aacgaccgtc gcgctgacga gcatagatac tgctctcttc ttcgccaatc
    18421 agcgagacat ctgcgccaat ctggcgcata tcagcctgaa tgatttccgc catcgatttg
    18481 cttaacgcat cggtgccgat gaacgacagt tcaatgcgca gcggctgacc atttttctcg
    18541 cggatgtctt tgcccgcagg cagcgtccaa ccggcttttt ccagcaacgc tttcgctttc
    18601 tgcggatcgt actggcgcgg tttcaggccg aggttggcgt agggcacaga aggggcaaac
    18661 agggtgtcgg cgacctgctg ggtgccatac aacgcgttat caatcagcga ttttttgttt
    18721 accgcgtaat taagagcttc acgtactgcc agctcattgg tgggggcttt ggcggtattg
    18781 agcgccagca tcacggtttc gatcggctgt gacagttggg tgtggtaagc cggattctgg
    18841 ctaaagcggg cgaaggtatc gagcggtaat aacccttcgt ttccgtacag caggtcgata
    18901 tcgccagttt caaacgccac cgcgcgggta gtcgggtccg ggatgacgtt aaaggtgatc
    18961 tttttaatcg ctggcttttc gccccagtag ttttcgttac ggacgaagac atcgtactga
    19021 ttcagtttcg attcctgcaa aatccatggt ccggtgccaa tcggcgcttt aattccgttc
    19081 atggtttcat ggtttttaaa ctgcgaggga gcgataaaac ggaaaggacg gggcagggcc
    19141 agttcttgca ggaaaggata gtaggcgctt ttcagggtaa tttgcagctc tgttttactg
    19201 agtgctttaa catcaacaat ctggtttgcc agctccagcc aggcgtgacg ttgacggtta
    19261 tcgagcactg cgcggaagtt ttctgccgcc gcctcggcat cgaacggttc accgttggag
    19321 aatttcacgt catcacgcag ggtgaaggtc caggttttac catcttctga atgagtccag
    19381 ctttttgcca gccacgggat caccgaaccg tctgcctgat atttcaccaa tggttcataa
    19441 accatgctct gggcgaacat ctggttaggc gtgtaaaggt gcgggtttag tggcccgaca
    19501 ttcaccggcc aggcggtagt gatttcatct ggtgcagcgg catggacgat aaaagacgca
    19561 caagccagca gcgcaaatag agtgcggcgg agtgtggaga gcatggtaac cccaatggat
    19621 taaaatagat ggcggaaata agtatgacga ttttaagtat tcgtcatact gattacctgt
    19681 tctggatcaa tagatgggca gtcgggtggg cggatcagtt aactgaatcg atccattgca
    19741 cactgtcggc ggtgagcgta aagggggtgg gggtgcagat cgccaggctt aaattttcaa
    19801 gctgacaatg gctgactgac agcgaggagt gataggtgct gtctacgctg acgatttgcc
    19861 aggcgctgcc gccacgctgt ttaacgatgg cttctttgcg cgtccagatg cgccagaaca
    19921 tttccagttg ctgatcagga tgcacggcgt ccatctcagc gtgttccccg aggctgaata
    19981 cggcgttcgc cagccagcgc cagttggcgc gcgggcgaat cacttcgata tcgcagccga
    20041 cttcgccttc atcactcaac agcagagcga tatcgtcacc gctatggctt aagttgaacc
    20101 atagcggcgt ttccggcgcg aatgcaggtt tgccttgttc gccatagatg atctccggta
    20161 gcggggaaag cgtgtgcgaa agcaatgcac gccccgccag ccagcgttcg cgtcgtggac
    20221 cttgcggtgc ttgctcgcgt aaacccggtg gcagtggagc tgcgcttaag gtcgaaactt
    20281 tccccagaac tatccgatac atatcagggc caacgtttaa tggaaaatga aagtgcgtat
    20341 cgtatcactt gtcgcctcat cccggtaacc gacttttcgg tctgcccggc cccagtaaaa
    20401 tcgccagttt gctgccacct ttcgtcgttt ccatccagat tttacacacg ctggttaatg
    20461 gcaccgaaag tagcatccct accgggccga gcagccatcc ccagattaac aatgaaagaa
    20521 ataccaccat ggtggacatc cccaggcgat ggcccatcat ccgtggctct aaaatattgc
    20581 cgatgaccat atggacaact aaaaacaatg cgccgaccag aatacattcg taaataccat
    20641 taaacagcag cacctgaatc attggcggta cggcggaaat taccgcgccg atattgggca
    20701 cgtagttaag caaaaacgcc agtactgccc acatcagcgc aaactgtacc cccatcagct
    20761 ccagccccag ccagacgatg acacctgtcc ataaactgag tagcgtcttc aatgcaagat
    20821 agtgcgaaac gcctttaagt gcgcggtgta atcccgcgat gtgaatctgt gggttattca
    20881 gcgcaaaacg cattttgtaa gggacgtggc gcacttcaaa cagcataaaa actacggtca
    20941 tcaccagcaa aagcacgctc gccattgccc cggaaagccc ggtcattagc gctgtggtga
    21001 aggtaaccac tttttccgag tccatccgct gcagcattcg ctccggcgac atatgcaaat
    21061 taagaaaagg caacatctcc tgcaatttaa aaagtttgcg cgtcaactcc ttattaaact
    21121 tcggcagcat agagataaat tcgttaaacg atgccgccag tacgccgacc agcgcagtta
    21181 gtgcgatcag catcaccacc accacaatcg taatggcaat ggggcgttgt actccccgac
    21241 gaataaacca ggtgacgagc gggttgagga cgatggcaaa aaacagcgcc agtaacagct
    21301 gcacaatgat atctgccgct gcgtgaatgc ccgcgaggat cactaccagc gaggccagct
    21361 tgagcagaat gtgcatgccc gttttatcgg gttgaggggt ttccattggg gcttccttgt
    21421 gactttttgt attaagtgta gcgggagtca cgccagcaat attctgattc ttactgctga
    21481 ttttcacgtc agcacgtggt aaaagtgaaa cactgttgta aaaatgtggt gatcctcatg
    21541 cccgaacccg tagccgaacc cgcgctaaac ggattgcgcc tgaatttgcg cattgtctct
    21601 atagtcatgt ttaacttcgc cagctacctc accatcgggt tgccgctcgc tgtattaccg
    21661 ggctatgtcc atgatgtgat gggctttagc gctttctggg caggattggt tatcagcctg
    21721 caatatttcg ccaccttgct gagccgtcct catgccggac gttacgccga tttgctgggc
    21781 cccaaaaaga ttgtcgtctt cggtttatgc ggctgctttt tgagcggtct gggatatctg
    21841 acggcaggat taaccgccag tctgcccgtc atcagcctgt tattactttg cctgggacgc
    21901 gtgatccttg ggattgggca aagttttgcc ggaacgggat cgaccctgtg gggcgttggc
    21961 gtggttggct cgctgcatat cgggcgggtg atttcgtgga acggcattgt cacttacggg
    22021 gcgatggcga tgggtgcgcc gttaggcgtc gtgttttatc actggggcgg cttgcaggcg
    22081 ttagcgttaa tcattatggg cgtggcgctg gtggccattt tgttggcgat cccgcgtccg
    22141 acggtaaaag ccagtaaagg caaaccgctg ccgtttcgcg cggtgcttgg gagcgtctgg
    22201 ctgtacggta tggcgctggc actggcttcc gccggatttg gcgtcatcgc cacctttatc
    22261 acgctgtttt atgacgctaa aggttgggac ggtgcggctt tcgcgctgac gctgtttagc
    22321 tgtgcgtttg tcggtacgcg tttgttattc cctaacggca ttaaccgtat cggtggctta
    22381 aacgtagcga tgatttgctt tagcgttgag ataatcggcc tgctactggt tggcgtggcg
    22441 actatgccgt ggatggcgaa aatcggcgtc ttactggcgg gggccgggtt ttcgctggtg
    22501 ttcccggcat tgggtgtagt ggcggtaaaa gcggttccgc agcaaaatca gggggcggcg
    22561 ctggcaactt acaccgtatt tatggattta tcgcttggcg tgactggacc actggctggg
    22621 ctggtgatga gctgggcggg cgtaccggtg atttatctgg cggcggcggg actggtcgca
    22681 atcgcgttat tactgacgtg gcgattaaaa aaacggcctc cggaacacgt ccctgaggcc
    22741 gcctcatcat cttaaaactt actgaataac cagcgtatta atgatgtttt ctgcggtggt
    22801 ctgcgctttt tgctgatcgt cagcgggcag cgtaatttgc atggtcagca gttgattacc
    22861 cacgttaccc agaataacgg aagagtacgc cgtctggcct ttcgcggaga taatactgtc
    22921 taactgctgc attttgtgac ctttcagctc aatggcttta ttggttacca cttgcagctg
    22981 cggatcgcgg ctacgttgct gatcttccag acgcttcgcc agcaccgcca gatcttcttt
    23041 cggatcatcg cccatgatga cgatgactgc tttctgcccg gtggcgtcgg accagacatg
    23101 catgttattg gcctgcgttc ccagcttacc gctctggtcg gtcatatccg ctggcagcga
    23161 gaaacttaac ttgccatcaa gcaggttgac gggattcccg gtagcgttac tttccgcgac
    23221 cgaaccctgc gccgtagcgt tagtgtcttt atcatcacag gccgcaagcc ccataaccag
    23281 caggccaatt ccgacatatt taaccagatt gcgcattgac ttcttccttt cgataaacgg
    23341 ccataacggc tcattcatcc atcttatcac aactctgata acgaaccttt aactcgcctg
    23401 caaagcgttg atttcggatt tatctgccag tcttttcaac agcatattga gtaatacgcc
    23461 atacattggc aggaagaaaa cgatactgat taacactttg aaacagtaat cgaccagcgc
    23521 gatttccatc cagtgttcag ccataaaggc atccgggcta cgccagaagg caatgaagaa
    23581 aaaggccagc gtgtcactga cgttaccgaa cagtgtggac gctgtcggtg ccagccacca
    23641 gcggcgactt tgacgcaggc ggttaaaaac gtgcacgtcg aggatttgcc ccagcgcgta
    23701 ggccatgaaa ctggcggtgg cgatacgggc gacaaacagg ttgaagtggg cgagtgcgcc
    23761 gaatccctgc catgaaccca tatagaacag cgacgagatg acataggaga ttaataacgc
    23821 agggatcatt accgcgaaga taatgcgtcg ggccagcggt gcgccaaaaa tacgcacggt
    23881 caggtcggtc gcgagaaaga taaacggaaa actaaacgcg ccccaggtgg tatgaaaacc
    23941 aaaaatggag accggaagct ggaccagata gttactggag gtgatcacca gcagatgaaa
    24001 taacgataac cagaacaacg ccttatagcg ttgagtttgc gagaaaacgt tcatattgta
    24061 cctttttgat taaccattgg ggtgagggaa cccaatacgt acgacacgtc tgttatctta
    24121 acataataac gtgcttaccc ttttttcgag ccgccgcatg atactgcttt acgttgacaa
    24181 tgcaatggtt aattttcacg caatcgttaa cctggtttgc ttacggactc acagggcgta
    24241 aactagcgcc gtttttttaa gtgatgagaa gaaaatgacc gatctctttt ccagccctga
    24301 ccacacactc gacgcgcttg gcctgcgctg cccggaaccg gtgatgatgg tgcgcaaaac
    24361 cgtgcgcaat atgcagcctg gcgaaacttt actgattatc gccgacgatc cggcgacgac
    24421 ccgcgatatt cctgggtttt gtacctttat ggaacacgaa ctggttgcga aagagacgga
    24481 tggactgcct tatcgttatt tgattcgtaa aggcggttga tggggaaaga ttggcttcga
    24541 tgccgccttt tcccctcacc ctaaccctct ccccagagga gcgaggggac cgatcgcgct
    24601 caatgttgcg atcggtttgc cttatctcct gcgcaacaat cttaacgcat tcgctgttac
    24661 cagcacggtc gcaccggtat ctgccagcac cgccagccat agtccggtca tccctagcag
    24721 cgtggtgacg aggaagatcc ctttcagccc cagcgcaata gtgatgttct ggcggatatt
    24781 ggcgtgagtg gcgcgtgcca gttcaatcat ttgcaccagg ccgcgcaggt ggttatgggt
    24841 taatgctgcg tcggcggttt ccagcgccac gtctgtgcca ctgcccattg caatcccaat
    24901 ggcggcagct ttcatcgctg gcgcgtcgtt aataccatca ccgaccatcg ccaggggcgc
    24961 atgttgattc agcttggtca ccgctttgac tttatcttcc ggcaataggc ccgctttaaa
    25021 ctccagcccc agctccccgg caattgccgc cgctgcgcgt ggattatcgc cggtgaggat
    25081 cactccttta acccccagcg cgttcagttc actgatggca gttgctgcgt cggcgcgcag
    25141 ggtatcctgc aatgcaatga tacccagcac gtcatcatta cgtactacca gcacaaccgt
    25201 ttgcccggcg ctttccagtt cattaatcaa accagcaaat gcatcagcgg gatgtttccc
    25261 ggcagcgcaa atcaatacgc gctcaccgtt aacctgcgct tcaatgccag acccgaccag
    25321 cgcccgctgt gattcggcgg tgggaatggc gagttcagca acctgtgctt cgcgtacgat
    25381 ggcctgcgcc agtggatgcg tcgcgccttg ctcgaccgcc gccgccagtg tcagcagttc
    25441 agattcacta atacccgttg ccggatgaat cgcggtaacg cgcggtttac cgacggtcag
    25501 cgtaccggtt ttatcaaacg ccacctgagt aacacgaccc agctgttcca gcgccgctcc
    25561 gcctttaatc aacgccccac gacgcgctgc cgccgccagc ccggaggtaa tcgccgcagg
    25621 cgtggagata actaacgcac acgggcagcc aatcagcagc agcgtcagcc ctttataaat
    25681 ccactcctgc cagctggcgg caaacagcag cggtggcacc agcgtcacca gcagggcgac
    25741 ggccataatc gctggcgtat aaatacggct gaaacggtcg ataaaccgct caatgggggc
    25801 gcggcgctct tcggcttctt cgatcagttt cagaatccgg tcaatggcgc tggcacccgg
    25861 ttctgacagc acttccagcg ttaccagacg gtctacgctg gtggctcctg caggaacttt
    25921 atcgcccgtc gcgcgctcca ccggaatgga ttctccggtc agggcgcttt catcaaaact
    25981 ggcaaacggt gagagcagtt taccgtcggc aggcaaacgc ccacctgcgg cgacttcaat
    26041 cacatcgcca ggccgcaggc tgttaatcgc cacctcttcc cgctcaccgt tacgcaggcg
    26101 cgtggcggtt tctggtttca gcgccattaa cgcgctaacg ccctgacgcg cgcggctggc
    26161 ggcccagcct tccagtcgtt caccaatcaa aaacagcagc aacaccatcg cagcttcagc
    26221 cgttgcgcca ataaacagtg caccaatagc ggctacgctc attaaggttt caatggcgaa
    26281 gtagctgccg gatttgatca gccgtaatgc ctgacgagca atcgggtaca gcccaaccag
    26341 cgtggtcgcg ataaacgcca gttgcccaaa cggatgatta aattgctcca gaccccagct
    26401 gattgccatc atcacgatta gcgtaatcag cggcagattc tctttcaggc gcgatgcttg
    26461 tggctcgtcg gcggcctgct catcgcgcag ggaatagccc gctttttgca ccgcagattc
    26521 aacctgggca cggatgtcat tgtcggcatc gaccaccagt ttttcggtgg cgaacagtac
    26581 ctgcacctga ttcacacctg caagctggcg cacggcattt tctaccttgc gcgcacaggc
    26641 ggcgcagtcc atgccgctga ctttccagct atagcgggtg ccggagacgt tttcagagag
    26701 cgttggcgag ctggaacatg cgccgtcgca gcaacagtcg ttggcgttct gtaccgtggt
    26761 tagcggtttg aacgcagcaa attgaggggc tttcttgccg tgattgtcag gagtcgacat
    26821 ggcatcctcc ggttaagttt tttctcatta accgaaggat acactctgga gtcgactcca
    26881 gagtcaagtt ttatcagaga tacagcgagc ggacgatgag gaaatgaccg gcaaagtagc
    26941 aggccgcagc aatcgcgtta tctgcccgga agcggcggcg atagtggcta cccagccaga
    27001 caaagttact gataaacagc aatgaagcgc caacaaacgc agagagtgcc ggagcggtcg
    27061 gacggaagaa ccacagttca cctgccagcc acaccatcac cagcgtcatg ccgataaacg
    27121 tgcagatagg ccaacgatac tcttccagtc gcgtccagat aatcgccagt aacagcgcgc
    27181 ccagaaccag caacaccagt ggcagaggcc agaagaaaga gagcgtcatc tgactggcga
    27241 aatagatggt gtacagcagg tgcgagagga aaaacgcgcc gatggcgtac atcagacgtt
    27301 gacgtggcaa cagggttagc gcatcgccca gcagtgaggc gcacagccct gccagcacca
    27361 gatagctaat ggcgtcgaac atcggcgctt gccaggccag taacagcagg agaagaaggg
    27421 ttaacggttt aaacacccag cgttgccagg ttggcccacg atacgatgca tccacagata
    27481 gccatgcgga aagacagaca gcgataaacg accaaagcat cttagttcct tgaattcgtt
    27541 attttttcgt aagcggaatg cctacggtct tgcttccagt ttagtggcga gggtggacgg
    27601 atgacaacac cataactggc agggtatgct tatttccgca ttttccgatg agggataaag
    27661 atgagcaaac cacctctttt ctttattgtt atcattggct taattgtcgt cgccgcatcg
    27721 tttcgtttta tgcaacagcg acgggaaaaa gctgataatg atatggctcc gctccagcaa
    27781 aagctggtgg tggtgagcaa caagcgggaa aaaccgatta acgatcgccg ttcgcgccag
    27841 caggaagtga ctccggcagg caccagtatg cgctatgagg caagcttcaa accgcaaagc
    27901 ggaggaatgg agcagacgtt tcgcctcgac gcccagcagt accacgccct gacagtgggc
    27961 gataaaggta cgctgagcta taaaggaacg cgctttgtca gctttgtagg cgaacaataa
    28021 ggttattttt taactttaaa tttcttctgc cagaccagca gttcaaacac gccgaaaagg
    28081 aaaatccgca ccttttcggc ggtggtcatc tgcgggccat ctttcggtaa agtggatttc
    28141 aatagcgcca gttgcatacc atgcatcagc acggtaaaaa tcagcgccac gttaacgaaa
    28201 atattcagcg ggcgcgggaa gggatgcacc agattgagga ttaaaaatcc ccaaacgcag
    28261 agcattaaca aacgaccaat attaatcagc atcactttct ccttgtgctt cgcgttgata
    28321 cagccgataa gccacctgac ccgccacttt ttcccgatgt aatgaccagt ttgccggaac
    28381 agtgggcaga ccgttttcga cttcgctttc gacataaatc agggcttcgt cagccagcca
    28441 gccgttatct tccagtaaat ttatcgtctc ttctaacaag ccacggcgga acggtggatc
    28501 gacaaacacg atattatgcg gtgtgccttt ttgcgccagg aatgacattg cgttgctgtt
    28561 caccacgcgt gcattgcctg cttttagtgt cgccagattc ttaattaact gctgagaaac
    28621 tgcgcgatcc atctcaatca acgtggcccc cgcagcgtag cgcgataacg cttccagccc
    28681 cagcgcgccg ctcccggcga agcaatccag acattgggcg tcaacaatga ccggagccag
    28741 ccagttaaac aacgtttcgc gtacgcggtc ggtggtgggg cgcagacctg ggctatcagg
    28801 aaccgggagt ttacggcctc gccactgccc gccaataatg cggatttggc cgctgccgga
    28861 atgattcggt tttttcatga taaattgctc aatccgccag ataacacata cttgcaggcg
    28921 gtgatgtgaa ttaagttaag tgatagacta tttcatcatt tttttagctg ctatgtacat
    28981 agcgttaacg ctgtgccatg aagcaacagc gaggagtgta gtcgcaaatg gcgaaagaaa
    29041 aaaaacgtgg ctttttttcc tggctgggct ttggtcaaaa agagcagacc ccggaaaaag
    29101 agacagaagt tcagaatgaa caaccggttg tagaagaaat cgttcaggcg caagagcctg
    29161 tgaaggcttc tgaacaagcc gtcgaagagc agccgcaggc gcatactgaa gccgaggcgg
    29221 aaacttttgc tgccgacgtt gtggaagtca ctgaacaggt tgctgaaagt gaaaaagcgc
    29281 agcctgaagc ggaagtcgtt gcacagccgg aaccggtcgt agaagaaacg ccggagccag
    29341 tggctatcga gcgtgaagag ctgccgttgc cggaagacgt caacgccgaa gaggtttcgc
    29401 cagaagagtg gcaggctgaa gcggaaaccg tagagattgt cgaagcggcg gaagaagaag
    29461 cggctaaaga agaaatcacc gacgaagagc tggaagcaca ggcgctggct gccgaagcgg
    29521 cagaagaggc ggtgatggtg gttcctccgg tagaagagca gccggtggaa gaaatcgctc
    29581 aggagcagga aaaaccgacc aaagaaggtt tcttcgcgcg cctgaaacgc agcctgttaa
    29641 aaaccaaaga aaatctcggt tccggattta tcagcctgtt ccgcggtaaa aaaatcgacg
    29701 atgatctgtt tgaggagctg gaagaacagc tgttgatcgc cgatgtgggc gtggaaacca
    29761 cacgtaaaat tatcaccaat ctgacggaag gcgcatcccg caagcagctt cgtgatgccg
    29821 aggcgctcta tggcctgctg aaagaagaga tgggcgagat tctggcgaaa gtcgatgagc
    29881 cgctgaatgt tgaaggtaaa acgccgttcg tgatcctgat ggtgggcgtc aacggtgtgg
    29941 gtaaaaccac gacgattggt aagctggcgc gtcagtttga gcagcagggt aaatcggtga
    30001 tgctggcggc gggcgatact ttccgtgcag cagcggttga acagcttcag gtctggggtc
    30061 agcgcaacaa tattccggtg attgcccagc atactggtgc ggattccgcc tctgttatct
    30121 tcgacgccat tcaggcagct aaagcgcgta atatcgacgt cctgattgcc gataccgccg
    30181 gacgtctgca gaacaaatcg cacctgatgg aagagttgaa gaaaatcgtc cgcgtgatga
    30241 agaaactcga cgttgaagcg ccgcatgaag ttatgctgac tatcgatgcc agcaccgggc
    30301 agaacgcggt aagccaggcc aaactgttcc atgaagctgt tggcttaacc ggcatcacgc
    30361 taacgaaact ggacggcacg gcgaaaggcg gggtaatttt ctcggtggct gaccagtttg
    30421 gtatccctat ccgctacatt ggtgtcggcg aacgtattga ggatttgcgt ccgtttaagg
    30481 cggacgactt tatagaggca ctttttgccc gagaggatta acaatgattc gctttgaaca
    30541 tgtcagcaag gcttatctcg gtgggagaca ggcgctgcag ggcgttacgt tccatatgca
    30601 gccgggtgag atggcgtttc tgaccggtca ttccggcgca gggaaaagta ccctcctgaa
    30661 gctgatctgt gggattgagc ggcccagcgc cgggaaaatc tggtttagcg gccatgacat
    30721 cacgcgtctg aaaaaccgtg aagttccgtt tctgcgccgc cagattggca tgattttcca
    30781 ggatcaccat ctactgatgg accgtactgt ctacgataac gtggcaatcc cgctgattat
    30841 cgccggtgcc agcggtgacg atattcgtcg ccgggtgtcg gcggcactgg ataaagtcgg
    30901 gctactggac aaagcgaaga acttccctat tcagctttct ggcggtgaac aacagcgtgt
    30961 tggcattgcc cgcgcggtgg tgaacaagcc cgcggtactg ctggcggacg aaccgactgg
    31021 taacctggac gacgcgttgt cggaagggat tctacgtctg tttgaagagt ttaaccgcgt
    31081 tggggtaacc gtattgatgg caacgcacga catcaacctg atctcgcggc gttcctatcg
    31141 catgctcacc ctgagcgatg gtcacttgca tggaggcgtg ggccatgaat aagcgcgatg
    31201 caatcaatca tattcggcag tttggcgggc gtctggatcg cttccgtaaa tcggtcggcg
    31261 gctctggcga cggcggtcgt aacgcgccaa aacgcgcgaa atcctcgcca aaaccggtaa
    31321 atcgcaaaac caacgttttc aacgaacagg tgcgctatgc cttccacggc gcattgcagg
    31381 atctgaaaag caaaccgttc gccacgtttt taacggtgat ggttatcgcc atctccctga
    31441 cgctgcccag cgtctgttat atggtgtaca aaaacgttaa ccaggcggcg acgcaatatt
    31501 atccgtcacc gcaaatcact gtttacttgc aaaaaacgct ggacgatgac gccgcagcag
    31561 gcgtggtagc acagctacag gccgagcagg gcgtggagaa agtgaactat ctttctcgtg
    31621 aagacgcact gggcgagttc cgtaactggt ctggttttgg tggtgcgctg gatatgctgg
    31681 aagaaaaccc gcttccggca gtggcggtgg tgatcccgaa actcgatttt caggggacgg
    31741 aatcactgaa tacgctgcgt gatcgtatca cccagattaa cggcattgac gaagtgcgga
    31801 tggatgacag ctggtttgcc cgtctggcgg cgttgaccgg gctggtcggg cgcgtttccg
    31861 cgatgatcgg cgtgttgatg gtggcagcag tgttcctcgt catcggcaac agtgtgcgtc
    31921 tgagcatctt tgctcgccgt gactccatta acgtgcagaa actgattggt gcgacggatg
    31981 gtttcatcct gcgcccgttc ctgtacggag gcgcattgct gggattttct ggcgcattgc
    32041 tgtcattaat tttgtcagaa attctggtac tgcgtttgtc atcggcggtt gcagaagtgg
    32101 cacaggtttt cggaacgaag tttgatatca atggtttatc gttcgatgaa tgcctgctat
    32161 tgctgctggt atgctcgatg attggctggg tggcagcgtg gcttgccacg gtacaacatt
    32221 tacgccactt tacgcctgaa taataaaagc gtgttatact ctttccctgc aatgggttcc
    32281 gtagcaggga aagagatccc gttgtctctt cccggtattt catctctatg tcacattttg
    32341 tgcgtaattt attcacaagc ttgcattgaa cttgtggata aaatcacggt ctgataaaac
    32401 agtgaatgat aacctcgttg ctcttaagct ctggcacagt tgttgctacc actgaagcgc
    32461 cagaagatat cgattgagag gatttgaatg actgacaaaa tgcaaagttt agctttagcc
    32521 ccagttggca acctggattc ctacatccgg gcagctaacg cgtggccgat gttgtcggct
    32581 gacgaggagc gggcgctggc tgaaaagctg cattaccatg gcgatctgga agcagctaaa
    32641 acgctgatcc tgtctcacct gcggtttgtt gttcatattg ctcgtaatta tgcgggctat
    32701 ggcctgccac aggcggattt gattcaggaa ggtaacatcg gcctgatgaa agcagtgcgc
    32761 cgtttcaacc cggaagtggg tgtgcgcctg gtctccttcg ccgttcactg gatcaaagca
    32821 gagatccacg aatacgttct gcgtaactgg cgtatcgtca aagttgcgac caccaaagcg
    32881 cagcgcaaac tgttcttcaa cctgcgtaaa actaagcagc gtctgggctg gtttaaccag
    32941 gatgaagtcg aaatggtggc ccgtgaactg ggcgtaacca gcaaagacgt tcgtgagatg
    33001 gaatcacgta tggcggcaca ggacatgacc tttgacctgt cttccgacga cgattccgac
    33061 agccagccga tggcaccggt gctctatctg caggataaat catctaactt tgccgacggc
    33121 atcgaagatg ataactggga agagcaggcg gcaaaccgtc tgaccgacgc gatgcaaggt
    33181 ctggacgaac gcagccagga catcatccgc gcgcgctggc tggacgaaga caacaagtcc
    33241 acgttgcagg aactggctga ccgttacggt gtttccgctg aacgtgtgcg ccaactggaa
    33301 aagaacgcga tgaaaaaact tcgcgccgct attgaagcgt aatttccgct attaagcaga
    33361 gaaccctgga tgagagtccg gggtttttgt tttttgggcc tctacaataa tcaattcccc
    33421 ctccggcaaa acgtcaatcc ccacgcagat tgttaataaa ctgtcaaaat agctattcca
    33481 atatcataaa aatggggtat gttttagcag agtattctgc taaagcacgg gtagtcatgc
    33541 ataaaacgaa ataaagtgct gaatcacaac accacaacac acgtaataac cagaagaatg
    33601 gggattctca ggatgaacat aaagggtaaa gcgttactgg caggatgtat cgcgctggca
    33661 ttcagcaata tggctctggc agaagatatt aaagtcgcgg tcgtgggcgc aatgtccggt
    33721 ccggttgcgc agtacggtga ccaggagttt accggcgcag agcaggcggt tgcggatatc
    33781 aacgctaaag gcggcattaa aggcaacaaa ctgcaaatcg taaaatatga cgatgcctgt
    33841 gacccgaaac aggcggttgc ggtggcgaac aaagtcgtta acgacggcat taaatatgtg
    33901 attggtcacc tctgttcttc atcaacgcag cctgcgtctg acatctacga agacgaaggc
    33961 attttaatga tcaccccagc ggcaaccgcg ccggagctga ccgcccgtgg ctatcagctg
    34021 atcctgcgca ccaccggcct ggactccgac caggggccga cggcggcgaa atatattctt
    34081 gagaaagtga aaccgcagcg tattgctatc gttcacgaca aacagcaata cggcgaaggt
    34141 ctggcgcgag cggtgcagga cggcctgaag aaaggcaatg ctaacgtggt gttctttgat
    34201 ggtatcaccg ccggggaaaa agatttctca acgctggtgg cccgtctgaa aaaagagaat
    34261 atcgacttcg tttactacgg cggttatcac ccggaaatgg ggcaaatcct gcgtcaggca
    34321 cgcgcggcag ggctgaaaac tcagtttatg gggccggaag gtgtggctaa cgtttcgctg
    34381 tctaacattg cgggcgaatc agcggaaggg ctgctggtga ccaagccgaa gaactacgat
    34441 caggttccgg cgaacaaacc cattgttgac gccatcaaag cgaaaaaaca ggacccaagc
    34501 ggcgcattcg tttggaccac ctacgccgcg ctgcaatctt tgcaggcggg cctgaatcag
    34561 tctgacgatc cggctgagat cgccaaatac ctgaaagcga actccgtgga taccgtgatg
    34621 ggtccgctga cgtgggatga gaaaggtgat ctgaaaggct ttgagttcgg cgtatttgac
    34681 tggcacgcca acggcacggc gaccgatgcg aagtaatcat taatcggcaa ctttgggttg
    34741 ccgccaaatt gctaatatcg agtacgttgc ttcatgccgg atgcggcgta aacgccttat
    34801 ccggcctaca agatccaaag aaatcagtaa attgcaacac acattgtagg cctgataagc
    34861 gtagcgcatc aggcaatttc tcgttggtca tcacttttga aatcaacttg acgattaacg
    34921 cttctcccag ccgccctgtt gcgccgtaaa ccccagcgcc tgcataaacg ccgtcatcac
    34981 accgcgatct tccacgcctg catccgccat ccaccagcat gaaacggcag gattgttacg
    35041 caaaacctct tccagcagat attgccccac accgcgacgg cgggtgactt cccgcacgcg
    35101 cagggaatcc agtgctccct cggtgccgct taaggttacc cgcacggccg ctagcaggcg
    35161 ctcgttaaaa cgcgcggcgt agatgcggtg gttatcgtca acctgtaaag aggaagggga
    35221 atactccggc cagatctttt gcaggtcaat ccggtcctgg tcgctaaagt tttctaatcg
    35281 aatgatggtc agcttcatgg gtaacccgtg taaatcacaa aagtggaacc agtgtagcga
    35341 aataatttaa tcggaggctt tctctttttt atttcttttg gcaggtgatt aattttttaa
    35401 cagcaataat tacaaagtta aaacattata gaatgaaaaa tacccagcat aatcccctga
    35461 atgatagtga attattccgc cctttgtgcc gttattttat gctgacaaag gcactttttt
    35521 ctgtttatct atcaataaat tcagaatatt atctgttctt aatcgactga aaaataggga
    35581 ttttaatcac tattatcaca aaatactgcg ctaaaccctt aatcagacag gcaaaaacag
    35641 tgcagtataa aaaaagaaca gtctgatttg ttaacacata aaaacaaagc aacacaacat
    35701 cacgaatggg gatttttgac tatgaaacgg aatgcgaaaa ctatcatcgc agggatgatt
    35761 gcactggcaa tttcacacac cgctatggct gacgatatta aagttgccgt tgtcggcgcg
    35821 atgtccggcc cgattgccca gtggggcgat atggaattta acggcgcgcg tcaggcgatt
    35881 aaagacatta atgccaaagg gggaattaaa ggcgataagc tggtgggcgt ggaatatgac
    35941 gacgcctgcg acccgaaaca agccgttgcg gtcgccaaca aaatcgttaa cgacggcatt
    36001 aaatacgtta ttggtcatct gtgttcttct tctacccaac ctgcgtcaga tatctacgaa
    36061 gacgaaggta ttctgatgat ctcgccggga gcgaccaacc cggagctgac ccaacgcggt
    36121 tatcaacaca ttatgcgtac tgccgggctg gactcttccc aggggcctac ggcggcaaaa
    36181 tacattcttg agacggtgaa gccccagcgc atcgccatca ttcacgacaa acaacagtat
    36241 ggcgaagggc tggcgcgttc ggtgcaggac gggctaaaag cggctaacgc caacgtcgtc
    36301 ttcttcgacg gtattaccgc cggggagaaa gatttctccg cgctgatcgc ccgcctgaaa
    36361 aaagaaaaca tcgacttcgt ttactacggc ggttactacc cggaaatggg gcagatgctg
    36421 cgccaggccc gttccgttgg cctgaaaact cagtttatgg ggccggaagg tgtgggtaac
    36481 gcatcattgt cgaatattgc cggtgatgct gccgaaggca tgttggtcac tatgccaaaa
    36541 cgctatgacc aggatccggc aaaccagggc atcgttgatg cgctgaaagc agacaagaaa
    36601 gatccgtccg ggccttatgt ctggatcacc tacgcggcgg tgcaatctct ggcgactgcc
    36661 cttgagcgta ctggcagcga tgagccgctg gcgctggtga aagatttaaa agctaacggt
    36721 gcaaacaccg tgattgggcc gctgaactgg gatgaaaaag gcgatcttaa gggatttgat
    36781 tttggtgtct tccagtggca cgccgacggt tcatccacgg cagccaagtg atcatcccac
    36841 cgcccgtaaa atgcgggcgg gtttagaaag gttaccttat gtctgagcag tttttgtatt
    36901 tcttgcagca gatgtttaac ggcgtcacgc tgggcagtac ctacgcgctg atagccatcg
    36961 gctacaccat ggtttacggc attatcggca tgatcaactt cgcccacggc gaggtttata
    37021 tgattggcag ctacgtctca tttatgatca tcgccgcgct gatgatgatg ggcattgata
    37081 ccggctggct gctggtggcg gcgggattcg tcggcgcaat cgtcattgcc agcgcctacg
    37141 gctggagtat cgaacgggta gcctatcgcc cggtgcgtaa ctctaagcgc ctgattgcgc
    37201 tcatctcggc aatcggcatg tccatcttcc tgcaaaacta cgttagcctg accgaaggtt
    37261 cgcgtgacgt ggcgctgccc agtctgttta acgggcagtg ggtggtgggc catagcgaaa
    37321 acttctctgc ctctattact accatgcagg cggtgatttg gattgttacc ttcctcgcca
    37381 tgctggcgct gacgattttc attcgctatt cccgtatggg gcgcgcctgt cgtgcctgcg
    37441 cggaagatct gaaaatggcg agcctgcttg gcatcaacac cgaccgggtg attgcgctga
    37501 cctttgtgat tggcgcggcg atggcggcgg tggcgggtgt gctgctcggt cagttctacg
    37561 gtgtgattaa cccctacatc ggctttatgg ccgggatgaa agcctttacc gcggcggtgc
    37621 tcggcgggat tggcagcatt ccgggggcga tgattggcgg gctgatcctg gggattgcgg
    37681 aggcgctctc ttctgcctat ctgagtacgg aatataaaga tgtggtctca tttgccctgc
    37741 tgatcctggt actgctggtg atgccgaccg gtattctggg gcgcccggag gtagagaaag
    37801 tatgaaaccg atgcatattg caatggcgct gctctctgcc gcgatgttct ttatcctcgc
    37861 tggcgtcttt atgggcgtac agctggagct ggacggcacc aaactggtgg tcgacacggc
    37921 ttcggatgtc cgttggcagt gggtgtttat cggcacggcg gtggtctttt tcttccagat
    37981 tttgcgacct gctttccaga aagggttgaa aagcgtttcc gggccgaagt ttattctgcc
    38041 cgcgattgat ggctccacgg tgaagcagaa actgttcctc gtggcgctgt tggtgcttgc
    38101 ggtggcgtgg ccgtttatgg tttcacgcgg gacggtggat atcgccaccc tgaccatgat
    38161 ctacattatc ctcggcctcg ggctgaacgt ggtggtaggg ctttccggcc tgctggtgct
    38221 ggggtacggc ggtttttacg ccatcggcgc ttacactttt gcgctgctca atcactatta
    38281 cggcttgggc ttctggacct gtctgccgat tgccgggtta atggcagcgg cggcgggctt
    38341 cctgctcggc tttccggtgc tgcgtctgcg tggtgattat ctggcgatcg ttaccctcgg
    38401 cttcggcgaa attgtgcgca tattgctgct caataacacc gaaattaccg gcggcccgaa
    38461 cggaatcagt cagatcccga aaccgacttt cttcggcctt gagttcagcc gtaccgcccg
    38521 tgaaggcggt tgggacacgt tcagtaattt ctttggcctg aaatacgatc cctccgatcg
    38581 cgtcatcttc ctgtatctgg tggcgttgct gctggtggtg ctaagcctgt ttgtcattaa
    38641 ccgcctgctg cggatgccgc tggggcgtgc gtgggaagcg ttgcgtgaag atgagatcgc
    38701 ctgccgttcg ctgggcttaa gcccgcgtcg tatcaagctg accgctttta ccatcagtgc
    38761 cgcgtttgcc ggttttgccg gaacgctgtt tgctgcgcgc cagggctttg tcagcccgga
    38821 atccttcacc tttgctgaat cggcgtttgt actggcgata gtggtgctcg gcggtatggg
    38881 atcgcagttt gcggtgattc tggcggcaat tttgctggtg gtgtcgcgcg agttgatgcg
    38941 tgatttcaac gaatacagca tgttaatgct cggtggtttg atggtgctga tgatgatctg
    39001 gcgtccgcag ggcttgctgc ccatgacgcg cccgcaactg aagctgaaaa acggcgcagc
    39061 gaaaggagag caggcatgag tcagccatta ttatctgtga acggcctgat gatgcgcttc
    39121 ggcggcctgc tggcggtgaa caacgtcaat cttgaactgt acccgcagga gatcgtctcg
    39181 ttaatcggcc ctaacggtgc cggaaaaacc acggttttta actgcctgac cggtttctac
    39241 aaacccaccg gcggcaccat tttactgcgc gatcagcatc ttgaaggttt accggggcag
    39301 caaattgccc gcatgggcgt ggtgcgcacc ttccagcatg tgcgtctgtt ccgtgaaatg
    39361 acggtaattg aaaacctgct ggtggcgcag catcagcaac tgaaaaccgg gctgttctct
    39421 ggcctgttga aaacgccttc tttccgtcgc gcccagagcg aagcgctcga ccgcgccgcc
    39481 acctggcttg agcgcattgg tttgctggaa cacgccaacc gtcaggcgag taacctggcc
    39541 tatggtgacc aacgccgtct ggagattgcc cgctgcatgg tgacgcagcc ggagatttta
    39601 atgctcgacg aaccggcggc aggtcttaac ccaaaagaaa ccaaagagct ggatgagctg
    39661 attgccgaac tgcgcaatca tcacaacacc actatcttgt tgattgaaca cgatatgaag
    39721 ctggtgatgg ggatttcaga ccgaatttat gtggtcaatc aggggacgcc actggcaaac
    39781 ggtacgccgg agcaaatccg taataacccg gacgtgatcc gtgcctattt aggtgaggca
    39841 taagatggaa aaagtcatgt tgtcctttga caaagtcagc gcccactacg gcaaaatcca
    39901 ggcgctgcat gaggtgagcc tgcatatcaa tcagggcgag attgtcaccc tcattggcgc
    39961 gaacggggcg gggaaaacca ccttgctcgg cacgttatgc ggcgatccgc gcgctaccag
    40021 cgggcgaatt gtgtttgatg ataaagacat taccgactgg cagacggcga aaatcatgcg
    40081 cgaagcggta gcgattgtcc cggaagggcg tcgcgtcttc tcgcggatga cggtggaaga
    40141 gaacctggcg atgggcggct tttttgccga acgcgaccag ttccaggagc gcataaagtg
    40201 ggtgtatgaa ctgtttccac gtctgcatga gcgccgtgtt cagcgggcag gcaccatgtc
    40261 cggcggtgag caacaaatgc tggcgattgg tcgcgcgctg atgagcaacc cgcgtttgct
    40321 gctacttgat gagccatcgc tcggtcttgc gccgattatc atccagcaaa ttttcgacac
    40381 catcgagcag ctgcgcgagc aggggatgac tatcttcctc gtcgagcaga acgccaacca
    40441 ggcgctaaag ctggcggatc gcggctacgt gctggaaaac ggccatgtgg tgctctccga
    40501 taccggcgac gcgctgctgg cgaacgaagc agtgagaagt gcgtatttag gcgggtaata
    40561 acacgttgat tgataaggag tcaaaagact cctttgagac aggtgacaaa tgtaaaattg
    40621 cctgatgcgc tgcgcttatc aggcctactg ggtgagttgc aatatattga atttgcacga
    40681 tcttgtaggc cggataaggc gtttacgccg catccggcat gaaacgatga gtaatctgta
    40741 gagtttgatt cagaccttct attttccgct tatccgtgcc ccatctccca ttttccctca
    40801 cccacgccgt caccgccttg tcatctttct gacaccttac tatcttacaa atgtaacaaa
    40861 aaagttattt ttctgtaatt cgagcatgtc atgttacccc gcgagcataa aacgcgtgaa
    40921 ttcgcgcatt cggtacaaca agagagataa acgatgaaac cgttacatta tacagcttca
    40981 gcactggcgc tcggactggc gttaatgggg aatgcacagg cagtgacgac cattccgttc
    41041 tggcattcta tggaagggga actgggtaaa gaggtggatt ctctggccca acgttttaac
    41101 gccgaaaatc cggattacaa aattgtaccg acctataaag gcaactacga acagaattta
    41161 agcgcgggga ttgccgcatt tcgtaccggc aacgctccgg ctattttgca ggtttatgaa
    41221 gttggcaccg ccaccatgat ggcatcgaaa gccattaaac cggtatatga cgtgtttaaa
    41281 gaggcgggga ttcaattcga tgagtcgcag tttgtgccga cggtttccgg ttactactcc
    41341 gacagcaaaa cgggccactt actctcccag ccattcaaca gctcgacccc cgttctctat
    41401 tacaacaaag acgccttcaa gaaagcagga ttagacccgg aacaaccgcc gaaaacctgg
    41461 caggatctgg cggactatgc cgcgaaactg aaagcctccg gtatgaagtg cggctacgcc
    41521 agcggctggc agggctggat ccaactggaa aactttagcg cctggaacgg tctgccgttt
    41581 gccagcaaaa acaacggctt tgacggcacg gacgcggtgc tggagttcaa caagccggag
    41641 caggtgaaac acatcgccat gctcgaggag atgaacaaga agggcgactt cagctacgtc
    41701 ggtcgtaagg atgaatccac cgagaagttc tataacggtg attgcgcgat gaccaccgcc
    41761 tcttccggtt ctctcgctaa tattcgtgag tacgccaaat ttaactatgg cgtaggcatg
    41821 atgccttacg acgccgatgc gaaagatgca ccgcaaaacg ccattatcgg cggggccagc
    41881 ctgtgggtga tgcagggcaa aaataaagaa acgtataccg gcgtggcgaa gttcctcgac
    41941 ttcctcgcga agccagaaaa cgctgccgag tggcatcaga aaaccggtta tctgccaatc
    42001 accaaagcag cgtatgacct gacccgtgag cagggctttt acgagaaaaa cccaggggcg
    42061 gataccgcga cgcgtcagat gctgaataag ccgccgttgc cgttcaccaa agggctgcgt
    42121 ctgggcaaca tgccgcagat ccgcgtgatt gtggatgaag agctggagag cgtgtggacc
    42181 ggtaagaaga caccacagca ggcactggat accgccgttg agcgtggaaa tcagttgctg
    42241 cgccgctttg agaaatcgac gaagtcttaa tcagtgtaat gtcggatgcg tttcgcttat
    42301 ctgacctggc atcgcgtgta ggccggataa gcgaagcgca tccggcacag ttcaggaatt
    42361 aaccgtaatg tcatcatccc gtccggtgtt ccgctcgcgc tggctgcctt atctgctggt
    42421 cgcgccgcag ctcatcatca ccgttatctt ttttatctgg cctgcgggcg aagcgttgtg
    42481 gtactcgcta caaagcgtcg atccgtttgg tttctccagc cagtttgtcg gcctggataa
    42541 cttcgtcacg ctgttccatg acagctacta tctcgactcc ttctggacga cgataaaatt
    42601 cagcaccttt gtcaccgtca gcggtttgct ggtatcgctg ttctttgcgg cgctggtgga
    42661 gtacatcgtg cgcggcagcc gtttctatca aaccttaatg ttgctgcctt acgccgtggc
    42721 tcccgccgtt gccgccgtat tgtggatctt cctgtttaac cccggtcgcg ggctgatcac
    42781 ccattttctc gcggagttcg gctacgactg gaaccacgcg caaaacagcg gtcaggcaat
    42841 gtttctggtg gtgtttgcct cagtatggaa gcaaatcagc tacaacttcc tgttcttcta
    42901 tgccgcgctg caatccattc cccgttcgtt gatcgaagcc gcagccatcg acggtgcagg
    42961 gccgattcgc cgcttcttta agattgcgct gccgcttatc gccccggtga gtttcttcct
    43021 gctggtagtg aacctggtgt atgccttctt cgacaccttc ccggtgatcg acgccgccac
    43081 gtccggcggg ccggttcagg ccaccacgac gctgatttat aagatctacc gcgaaggttt
    43141 taccggactg gatctggctt cgtctgccgc acagtcggtg gtgttgatgt tcctcgtcat
    43201 cgtgctgacg gtggtgcagt tccgctatgt tgaaagcaag gtgcgttacc aatgattgag
    43261 aaccgtccgt ggctgacgat attcagccat accatgctga tcctcgggat cgcggtgatc
    43321 ctcttcccgc tgtacgtggc gtttgtcgcg gcgacgctgg ataaacaggc cgtctatgcc
    43381 gcgccgatga cgctcatccc cggcacacat ctgctggaaa acatccacaa catctgggtg
    43441 aacggggtag gcacgaatag cgcgccgttc tggcggatgt tgcttaacag ctttgtgatg
    43501 gcgttcagca ttacgctcgg caaaattacc gtctcgatgc tctcggcatt tgccattgtc
    43561 tggtttcgtt ttccgctacg taacctcttc ttctggatga tttttatcac cctgatgctg
    43621 ccggttgaag tacgtatctt cccgacggtg gaagtcatcg ccaacctgca gatgctcgac
    43681 agctacgccg gtttaacgct gccgctgatg gcctcggcga ccgctacttt cctgttccgc
    43741 cagttcttta tgacgctgcc ggatgagctg gtggaagccg cgcggatcga cggcgcatcg
    43801 ccaatgcgct tcttttgcga catcgttttt ccgctctcca aaactaatct ggcggcgctg
    43861 tttgtgatca cctttatcta cggctggaat cagtatttgt ggccgttgtt gattattacc
    43921 gatgtggatc tcggcaccac cgtggcaggg atcaaaggga tgatcgctac aggcgaaggc
    43981 accacggaat ggaactcagt gatggcggcg atgttgttaa cgcttatccc tccggtggtg
    44041 attgttttag tgatgcagcg tgccttcgtg cgcggcctgg tcgatagtga gaaataagat
    44101 ggcaggactg aaattacagg cagtaaccaa aagctgggat ggtaaaaccc aggtcattaa
    44161 accgctgacc cttgatgtgg cggatggcga atttatcgtg atggtcgggc cgtctggctg
    44221 cgggaaatcg acgctgctgc gcatggttgc cgggctggag cgggtgacag aaggcgatat
    44281 ctggatcaac gaccagcgcg tgactgaaat ggagccaaaa gatcgcggga ttgcgatggt
    44341 gttccagaac tacgcgcttt atccgcatat gagtgtcgaa gaaaacatgg cgtgggggct
    44401 gaaaattcgc ggcatgggca agcagcaaat tgccgagcgc gttaaagaag cggcgcgcat
    44461 tctggagctg gacggtctgc tcaaatgtcg cccgcgcgag ctttccggcg gtcagcgcca
    44521 gcgtgtggcg atgggccgcg cgattgtgcg cgatccggcg gtgttcctgt ttgatgagcc
    44581 gctctctaac ctcgatgcca agctgcgcgt gcagatgcgt cttgaactgc aacagttgca
    44641 ccgtcgcctg aaaacgactt cactctacgt tactcacgat caggttgaag cgatgacgct
    44701 cgcccagcga gtaatggtga tgaacggcgg cgttgccgaa cagattggca caccagttga
    44761 agtctacgaa aagcccgcca gcctgtttgt agcgagtttt atcggcagtc cggcgatgaa
    44821 cctgctgaca ggccgcgtga ataccgaagg cacgcatttc gaactggacg gcggtatcgt
    44881 gctaccgcta aacggtggct accgtcagta tgccgggcgt aaaatgactc tcggcattcg
    44941 cccggaacat attgcgctaa gctcgcaagc agaaggtggc gtaccgctgg tgatggatac
    45001 gctggagatc ctcggcgcag ataacctggc gcacggacgc tggggcgagc agaagctggt
    45061 ggtgcgactg gcgcatcagg agcgcccgac ggcaggcagc acgctgtggc tgcatctggc
    45121 ggaaaatcag ctgcatcttt ttgatggtga aacaggacaa cgagtatgag taactggcct
    45181 tatccccgca tcgtcgctca tcgtggcggc ggtaagctgg cccccgaaaa caccctggcg
    45241 gcaatcgacg ttggggcaaa atacggtcat aagatgatcg aatttgacgc gaagttatcg
    45301 aaagatggcg agatcttcct gctccatgac gacaatctcg aacgcaccag caacggctgg
    45361 ggcgtcgcgg gtgaactgaa ctggcaggat ttactgcgcg tggatgcggg cagttggtac
    45421 agcaaagcgt ttaaaggtga gccgctgccg ttgctttcgc aggtggcgga acgctgtcgc
    45481 gaacacggga tgatggcgaa tatcgaaatc aaacccacca ctggcactgg accattaacg
    45541 ggcaaaatgg tggcgctggc ggcacgccaa ctgtgggccg gtatgacgcc gccgctgctg
    45601 tcatcgtttg agattgatgc tttagaagct gcacagctgg cggcaccgga actgccgcgt
    45661 ggtttattgc ttgatgagtg gcgcgacgac tggcgcgaac tgaccgcgcg gctgggctgc
    45721 gtctctattc atctcaatca taagttactc gataaagtgc gagtgatgca gttgaaagac
    45781 gccggactgc ggattctggt ttataccgtc aataaacccc agcgcgcggc agagttgctg
    45841 cgctggggcg tggattgcat ctgtaccgat gcgattgacg tgattggtcc gaactttacg
    45901 gcccaatagt tttcaacgga atgtcaggct gcggcgtgct gggctgattc agcatgtcgc
    45961 cgtttctcct ctccggcagc atatgctgct gattcaacga actatccgga ttacggttgc
    46021 tgtttaacat cccgccgttg gtgttgggca gcatttgctg ccgggcggga tttcgctccc
    46081 ccggctgtga ctgcaacacc cgctgagaat tattgtttat ctggttttct aaatgctgct
    46141 gttgcaactg agtttgcgtt ttcagttgct gattcagcat ccctttttgc tggatttgct
    46201 gagtctgcat ctgggtttgc atccgctgct ggctgggtat ctgatacccc ggctggttag
    46261 ggttgttcag agtattaatg ggctgtgcaa agccgacaaa cggcaggagt gccgtaagaa
    46321 tcagaagtcg tttcatcgcg tatcctcctc tgaagatatc ctttaagttt actcgcttcc
    46381 cgacaaaacg atgattaatt cagagttata taccaggctt agctggggtt gccccttaat
    46441 ctctggagaa taacgatgat aaaaccgacg tttttacgcc gggtggccat tgctgctctg
    46501 ctctcaggaa gttgttttag cgccgccgcc gcgcctcctg cgccgcccgt ctcgtatggt
    46561 gtggaggaag atgtcttcca cccggtacgc gcgaaacagg gaatggtagc gtctgtggac
    46621 gccactgcca ctcaggtggg ggtggatatt ctcaaggagg gcgggaatgc cgttgatgcc
    46681 gccgtggcgg tgggctacgc gctggcggta acgcatccgc aggcagggaa tctgggcggt
    46741 ggtggtttta tgttaatccg ctcgaaaaat ggcaatacca cggctatcaa tttccgcgaa
    46801 atggcacccg ccaaagcgac ccgcgatatg ttcctcgatg atcagggcaa cccggacagc
    46861 aaaaaatcac tcacttcgca tctggcttcc ggcacaccgg gtacggtagc aggtttctcg
    46921 ctggcgctgg ataaatacgg caccatgccg ctgaacaaag tcgtgcagcc cgcgtttaaa
    46981 ctggcacgcg atggttttat cgttaacgac gcgctggctg acgatctcaa aacctacggt
    47041 agcgaagtgt tgccgaatca cgaaaacagt aaagctatct tctggaaaga gggcgagccg
    47101 ctgaaaaagg gcgacacgct ggtgcaggcg aacctggcaa agagcctgga gatgattgct
    47161 gaaaacggcc cggacgaatt ctataaaggc acgattgcgg aacagatcgc ccaggagatg
    47221 cagaaaaacg gtggcttgat cactaaagaa gatttagcgg cctataaagc ggtcgaacgc
    47281 actccgataa gcggcgatta tcgcgggtat caggtttact ccatgccacc gccatcctcc
    47341 ggcgggatcc atatcgtaca aatcctcaat attctggaaa acttcgatat gaagaaatac
    47401 ggctttggca gcgccgatgc gatgcaaatc atggcagagg ctgagaaata tgcctacgcc
    47461 gaccgctcgg aatatcttgg cgacccggat tttgtcaaag tcccgtggca ggcgctgacc
    47521 aataaagcct atgccaaatc tattgccgag caaatcgata tcaataaagc gaaaccgtcc
    47581 agcgagattc gccctggcaa gcttgcgcct tatgagagta atcaaactac ccattactca
    47641 gtggtggata aagatggtaa cgcggtggcg gtgacctata cgctgaacac caccttcggt
    47701 acgggtattg tcgcgggcga gagcggtatt ctgcttaata accagatgga tgatttctcc
    47761 gccaaaccgg gcgtaccgaa cgtttacggg ctggtgggcg gtgatgccaa cgcggtcggg
    47821 ccgaataaac gcccgctgtc gtcgatgtca ccaaccattg tggtgaaaga cggtaaaacc
    47881 tggctggtta ccggtagccc tggcgggagt cggattatta ccaccgtgct gcaaatggtg
    47941 gtgaatagca tcgattatgg catgaatgtc gctgaagcga ccaatgcacc gcgcttccac
    48001 catcaatggt tgccggacga gctgcgtgtc gaaaaagggt ttagcccgga tacgctcaag
    48061 ctgctggaag caaaaggtca gaaagtggcg ctgaaagagg cgatgggcag tacacaaagc
    48121 attatggttg ggccggacgg tgagttgtac ggcgcatccg acccgcgctc ggtggatgat
    48181 ttaacggcgg ggtactaagg ttagcggccc tcttcgtggg aagagggcta ttttgtcagg
    48241 gcaagccgaa ggtagccttt tttatttcgt aatcctgtag atattcttcc agcggctttg
    48301 ccgttcccag agaatgaatt tcaccactgt ctttatcaat aataaaaggt gcgttaccag
    48361 ctaagcgcgc ggcctcatct ccagtttcga gaaattctcg tgcttcgaaa cagaaatacc
    48421 agccctggct aaagcgtcca tgtagagtaa tgacgaccgg gagatctgca tcatcaaggt
    48481 aatggttcgc tttcgcgaat gcgtcgtgat aagtaatcat aattataata aatattattg
    48541 ttgagtgtta tattattatt cctgtgtgat acattgagca aagacgcgtt catcttcgtc
    48601 aaagatatta ttaaatgctg gttttgaaaa aagttcatcg gataagatat agtcacgaaa
    48661 taagtatctg ctaatatttt atgatttctt tttcagaacg tcgaacggga ttttcttatt
    48721 taagatatca gaatcttatg attcgggtaa aattctaaat aaatcaacat gtcattaaaa
    48781 tcatcatagc cattagctat ttcggctaaa atagagacta catgtcttcg gtccatctca
    48841 cttaaggagt gtagttccgt tgtaagtttt tccatagctt gcactgctaa atttcgaaca
    48901 aggaattttc tgctggtaat ctctaaaaag atggcatggt ttacaatgat ttttgtttcc
    48961 ttttgattat tatgaacaac tgtccatgat ttcgtttaag aatgaagaga aatcactaaa
    49021 cgaactgaat atattttctg tgccaatatt atctctaatt tcaaaaaagt tacttttaat
    49081 gtcataagta aatattgaaa tgctatcatc cccgatcact aaccgttctt gtagatca
//
LOCUS       DAZUDJ010000034        46739 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.034, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000034 DAZUDJ010000000
VERSION     DAZUDJ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46739
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.034"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            61..1821
                     /gene="tssF"
                     /locus_tag="ACHY1N_002599"
     CDS             61..1821
                     /gene="tssF"
                     /locus_tag="ACHY1N_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HFS4044893.1"
                     /translation="MDDLTQRYYEAEMRYLREAGKEFAQAYPDRAAMLNLDKPGARDP
                     YVERLFEGFAFLMGSLREKLDDDLPELTEGLVSLLWPHYLRTIPSLSVVELSTDHRQM
                     KQSETLSDFQVLSRPVGERRTRCFYSATRDITLHPLALPDVSLQYEPDGRSVIRLRFE
                     CGPLVGDWSQIDLSRLPFYLNADSPVACALHRALTLGTQQFWLRLPGQDRRTLDAHFS
                     PLGFEDNDRLWPKGESAFSGYQLLLEYFTFREKFMFVALNGLELVAWPEGITGFEIDV
                     VLNENWPHDLPFDSDNIRLHCVPVINLFPLEADPLHLSPLENEFLLRPMRIQDGHTEI
                     YSVDNIISSRHTGSQAYVPFSSFRHRGGMLRHDAPERYYHTRVKRGPSGLHDTWLILG
                     GDAFDADRMLEDETLSLSLTGTNGHLPRKALQSTLLDRPVHASQNVLRVRNLCAPTQP
                     CYPPARDRFHWRVLSHLGSNFLSMMDNAEILRGTLALYDWTESEMNRRRLEAIVDVQH
                     SLIQRFERGFLLRGVDIQVTLDSNGFAGEGDITLFGELLHRFFALYADIHLFTQLTLI
                     LQPTGKCLQWTEHHSQRVPG"
     gene            1785..2864
                     /gene="tssG"
                     /locus_tag="ACHY1N_002600"
     CDS             1785..2864
                     /gene="tssG"
                     /locus_tag="ACHY1N_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HFS4044894.1"
                     /translation="MDRASQPARTGLTDRLAPDIARINFYRFCQFLEQSQQNAPLGST
                     DNPATDAVRFRPHPGMGFPVSELKNVERDAGNPNVPPTVRTTFLGLYGVDSPLPTAYL
                     DYITQRHDGHDAVMAFLDIFNHRFITQYYRIWRKYNYPASFEAGAMDDISRCLLGLIG
                     LGIPGSENHIATPVSRFLALLSVMRLPTRTAEGVTALVGLLAPLTKATVVPHDPQPVI
                     LPAPAGLSKNSRISLKTRTLLGRTGTDVNSQLLLKLYTEDAAEARGWLPGGQLHSDLL
                     VLLRVYLGWRCQARLQLTLPVSLLPAARLGKQRVQISRTGILRASFAAPATGTVTVSL
                     GRYQGLIPALSIRNRESMTHVSYSF"
     gene            2845..3381
                     /gene="tssJ"
                     /locus_tag="ACHY1N_002601"
     CDS             2845..3381
                     /gene="tssJ"
                     /locus_tag="ACHY1N_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HFS4044895.1"
                     /translation="MFPIRFKRPALLCMAMLTVVLSGCGLIQKVVDESKSVASAVFYK
                     QIKILHLDFFSRSALNTDAEDTPLSTMVHVWQLKTREDFDKADYDTLFMQEEKTLEKD
                     VLAKHTVWVKPEGTASLNVPLDKETQFVAIIGQFYHPDEKSDSWRLVIKRDELEADKP
                     RSIELMRSDLRLLPLKDK"
     gene            3385..3813
                     /gene="tssE"
                     /locus_tag="ACHY1N_002602"
     CDS             3385..3813
                     /gene="tssE"
                     /locus_tag="ACHY1N_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000106970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HFS4044896.1"
                     /translation="MSTPSLYEMLTFSFSGELPLEQVSERDQLILSVMDNMQRIINCR
                     AGTLAHLPDYGLPDLSLIHQGMVAGIHGLMRQIEETLLRYEPRLSQIQVELLPQPRPG
                     YLNYLIHAQLPDTGWIRFDGVFSPEGRIVLRHLKQQERAY"
     gene            3813..5189
                     /locus_tag="ACHY1N_002603"
     CDS             3813..5189
                     /locus_tag="ACHY1N_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VasL domain-containing protein"
                     /protein_id="HFS4044897.1"
                     /translation="MASNANFISQFVMGGDPCTYKESGELQAEMSKLTHPARPDVDWR
                     RVEKLSLALFRQNGVELQTQVCYVLAITRRQGLAGMADGLGSLDILLQRWADFWPVQV
                     HSRISLLSWVTEKMQQALRTLDIQYQDLPQIYRCVQHLSAIETTLQQCELWHMTKLDV
                     LAGQFRNTALRLERLAPQGAETTITPPELPRREMKQPEKSEESPQPVFATRPAQQNDK
                     DASPSAPSPEISWQRTWPIFMAGMVVMACLGGTGLWGWSQLNQPDALIQRIQLSVMPL
                     PQSLESGELAKLDVKDKALLAQDRTIAASQMQLEQLNKLPARWPLEQGYRQLRQLDAL
                     WPDNPQVRALNAQWRKQRELSALSTEALNGYAQAQSQLQRLSAQLDALDERKGRYLTG
                     SELKTAVYGIRQSLKEPPLEELLRQLEEQKQTGEVSPTLLTQIDTRLNQLLNRYVILL
                     DTKVEQSQ"
     gene            5254..5802
                     /locus_tag="ACHY1N_002604"
     CDS             5254..5802
                     /locus_tag="ACHY1N_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MucR family transcriptional regulator"
                     /protein_id="HFS4044898.1"
                     /translation="MYKKERNRPFETREEVLAYHKREKIPCLECGKLLIFLPRHIWFV
                     HGIRADEYRVKWNIPKHIALAGISYLEKQSEYMKARIAKGKLDPAEQIAMMRIKGRQL
                     KSDPDWRNRSGSILKKQYARRDILKNRVWERSPSIKSVSVELKTEAIRRMKNRKVVGE
                     KVQDIADDLNVSISRLYHWLKM"
     gene            complement(6148..7401)
                     /gene="amiC"
                     /locus_tag="ACHY1N_002605"
     CDS             complement(6148..7401)
                     /gene="amiC"
                     /locus_tag="ACHY1N_002605"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311701.2"
                     /note="Like AmiA, dependent on TAT (Twin-Arginine
                     Translocation) system for export; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiC"
                     /protein_id="HFS4044899.1"
                     /translation="MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPA
                     SSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSAR
                     VGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLED
                     YNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQI
                     ARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQ
                     QEVAESILAGIKAYFADGATLARRG"
     gene            7633..8964
                     /gene="argA"
                     /locus_tag="ACHY1N_002606"
     CDS             7633..8964
                     /gene="argA"
                     /locus_tag="ACHY1N_002606"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004042 - acetyl-CoA:L-glutamate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HFS4044900.1"
                     /translation="MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSS
                     IVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPLYHKNIRVTDAKTLELVKQAAG
                     TLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDA
                     IHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDD
                     GDIVSELFPNEAQARVEAQEEKGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGAL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERIAAQAKQS
                     GLSKLFVLTTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG"
     gene            complement(9026..10852)
                     /gene="recD"
                     /locus_tag="ACHY1N_002607"
     CDS             complement(9026..10852)
                     /gene="recD"
                     /locus_tag="ACHY1N_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HFS4044901.1"
                     /translation="MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSH
                     DAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMIL
                     CGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGK
                     ALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERAGQLSRLTG
                     THVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTD
                     IEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFG
                     VAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGT
                     RVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELV
                     YTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE"
     gene            complement(10852..14394)
                     /gene="recB"
                     /locus_tag="ACHY1N_002608"
     CDS             complement(10852..14394)
                     /gene="recB"
                     /locus_tag="ACHY1N_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HFS4044902.1"
                     /translation="MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYERLLE
                     EIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETL
                     ASRHAQIVARIATVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIDKISAWAEEE
                     TNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAE
                     IRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSA
                     PGMVNSVNKLFSQTDDAFMFREIPFIPVKSVGKNQALRFVFKGETQPAMKMWLMEGES
                     CGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQ
                     VRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLN
                     ALDIETLNNDEHAWDAVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGER
                     RLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITNFRVQDQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAED
                     LRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTC
                     IEALCDDDIAWQTAQTGDKQPWQVNDALTAELNARTLQRLPGDNWRVTSYSGLQQRGH
                     GIAQDLMPRLDVDAAGVVSVVEEPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNW
                     VQEKLELGGFESQWEPVLTEWITAVLQAPLNETGVSLNQLSDRDKQVEMEFYLPISEP
                     LIASQLDALIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGE
                     DSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYERHFGGVIYLFLRGV
                     DKEHPQQGIYTTRPNAGLIDLMDEMFAGMTLEEA"
     gene            complement(14387..17275)
                     /gene="ptrA"
                     /locus_tag="ACHY1N_002609"
     CDS             complement(14387..17275)
                     /gene="ptrA"
                     /locus_tag="ACHY1N_002609"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HFS4044903.1"
                     /translation="MPRSTWFKALLLLVALWAPLSQAETGWQPIQETIRKSDKDNRQY
                     QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP
                     QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQAL
                     KDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVE
                     GISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDEL
                     ANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMT
                     PQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPELNPYIP
                     DDFSLIKSDKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSARNQ
                     VMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGY
                     FSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSI
                     TLKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVD
                     KKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQ
                     AVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVV
                     EPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE"
     gene            complement(17451..20819)
                     /gene="recC"
                     /locus_tag="ACHY1N_002610"
     CDS             complement(17451..20819)
                     /gene="recC"
                     /locus_tag="ACHY1N_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HFS4044904.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEIPKESAFNKQSMSWKLMTLLPQL
                     LEREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPDWLAQWETGHLVEGLGE
                     AQAWQAPLWKALVEYTHQLGQPRWHRANLYQRFIETLESATTCPPGLPSRVFICGISA
                     LPPVYLQALQALGKHIEIHLLFTNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPL
                     FRDSENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESSQELDAFVDVTPDNL
                     LHNIQSDILELENRAVAGVNIEEFSRSDNKRPLDPLDSSITFHVCHSPQREVEVLHDR
                     LLAMLEEDPTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISDRRARQSHPV
                     LEAFISLLSLPDSRFVSEDVLALLDVPVLAARFDITEEGLRYLRQWVNESGIRWGIDD
                     DNVRELELPATGQHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFLPDAETEAAMTLIEQQWQAIIAEGL
                     GAQYGDAVPLSLLRDELAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEALISAQQKLYISYIGRSIQDNS
                     ERFPSVLVQELIDYIGQSHYLPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGE
                     RQSYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFWAHPVRAFFQMRLQVN
                     FRTEDSEIPDTEPFILEGLSRYQINQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGE
                     IFWETQCHEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQPDGLLRWRPSLL
                     SVAQGMQLWLEHLVYCASGGNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREG
                     MSAPLLVLPESGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVRGEGDDI
                     WYQRLWRQLTPETMEAIVEQSQRFLLPLFRFNQS"
     gene            complement(20832..21155)
                     /locus_tag="ACHY1N_002611"
     CDS             complement(20832..21155)
                     /locus_tag="ACHY1N_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HFS4044905.1"
                     /translation="MSASLKNQQGFSLPEVMVAMVLMVMIVTALSGIQRTLMNSLASR
                     NQYQQLWRHGWQQTQLRAISPPANWQVNRMQTSQAGCVSISVTLVSPGGREGEMTRLH
                     CPNRQ"
     gene            complement(21140..21547)
                     /locus_tag="ACHY1N_002612"
     CDS             complement(21140..21547)
                     /locus_tag="ACHY1N_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417301.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HFS4044906.1"
                     /translation="MNREKGVSSLALVLMLLVLGSLLLQGMSQQDRSFASRVSMESQS
                     LRRQAIVQSALAWGKMHSWQTQPAVQCSQYAGTDAQVCLRLLADNEALLIAGYEGVSL
                     WRTGEVIDGNIVFSPRGWSDFCPLKERALCQLP"
     gene            complement(21544..22107)
                     /locus_tag="ACHY1N_002613"
     CDS             complement(21544..22107)
                     /locus_tag="ACHY1N_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HFS4044907.1"
                     /translation="MPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRESLTSTRK
                     LALEDEIWLRVFTVAKHLQRAGYCHGSCTGEGLEIVGQGDCIIVQWDANSNGIWDREP
                     VKESDQIGFRLKEHVLETLRGATSCEGKGWDKVTNPDAIIIDTFQVVRQDVSGFSPVL
                     TVNMRAASKSEPQTVVDASYSVTGFNL"
     gene            complement(22098..22568)
                     /locus_tag="ACHY1N_002614"
     CDS             complement(22098..22568)
                     /locus_tag="ACHY1N_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HFS4044908.1"
                     /translation="MKTQRGYTLIETLVAMLILVMLSASGLYGWQYWQQSQRLWQTAS
                     QARDYLLYLREDANWHNRDHSISVIREGTLWCLVSSAAGANTCHGSSPLVFVPRWPEV
                     EMSDLTPSLAFFGLRNTAWAGHIRFKNSTGEWWLVVSPWGRLRLCQQGETEGCL"
     gene            complement(22753..23547)
                     /gene="thyA"
                     /locus_tag="ACHY1N_002615"
     CDS             complement(22753..23547)
                     /gene="thyA"
                     /locus_tag="ACHY1N_002615"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFS4044909.1"
                     /translation="MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHL
                     QLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI"
     gene            complement(23554..24429)
                     /gene="lgt"
                     /locus_tag="ACHY1N_002616"
     CDS             complement(23554..24429)
                     /gene="lgt"
                     /locus_tag="ACHY1N_002616"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFS4044910.1"
                     /translation="MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSF
                     HGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNF
                     PFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVI
                     MMVWAYRRSPQQHVS"
     gene            complement(24580..26826)
                     /gene="ptsP"
                     /locus_tag="ACHY1N_002617"
     CDS             complement(24580..26826)
                     /gene="ptsP"
                     /locus_tag="ACHY1N_002617"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFS4044911.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLT
                     ALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVI
                     EKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWPERFILVADELSATT
                     LAELPQDRLVGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLIVDGYRGE
                     LLVDPEPVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVD
                     EARRLIERAGREVEEMIGYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQ
                     YILAVDRNNTRVANIYDSLHPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARVKYLLRRIDYAEAENLAQRSLEAQLATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(26839..27369)
                     /gene="rppH"
                     /locus_tag="ACHY1N_002618"
     CDS             complement(26839..27369)
                     /gene="rppH"
                     /locus_tag="ACHY1N_002618"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HFS4044912.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQE
                     NTPKPQNASAYRRKRG"
     gene            complement(27722..27868)
                     /gene="ygdT"
                     /locus_tag="ACHY1N_002619"
     CDS             complement(27722..27868)
                     /gene="ygdT"
                     /locus_tag="ACHY1N_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgdT"
                     /protein_id="HFS4044913.1"
                     /translation="MLSTESWDNCEKPPLLFPFTALTCDETPVFSGSVLNLVAHSVDK
                     YGIG"
     gene            28054..28743
                     /gene="mutH"
                     /locus_tag="ACHY1N_002620"
     CDS             28054..28743
                     /gene="mutH"
                     /locus_tag="ACHY1N_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HFS4044914.1"
                     /translation="MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEE
                     LMDIIVLGQVERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFT
                     SALLARHFLIQ"
     gene            28812..29525
                     /locus_tag="ACHY1N_002621"
     CDS             28812..29525
                     /locus_tag="ACHY1N_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HFS4044915.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTIFSQEISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAM
                     FFSIAVESLNLIRNKKNPL"
     gene            29663..29881
                     /gene="ygdR"
                     /locus_tag="ACHY1N_002622"
     CDS             29663..29881
                     /gene="ygdR"
                     /locus_tag="ACHY1N_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YgdR"
                     /protein_id="HFS4044916.1"
                     /translation="MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDD
                     DTGLVSYHDQQGNAMQINRDDVSQIIER"
     gene            29989..31029
                     /locus_tag="ACHY1N_002623"
     CDS             29989..31029
                     /locus_tag="ACHY1N_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047834 - D-threo-aldose 1-dehydrogenase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HFS4044917.1"
                     /translation="MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGI
                     NLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPD
                     QALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT
                     LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVG
                     LAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAA
                     YVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEI
                     EAVHQVYTYPAP"
     gene            complement(31061..32254)
                     /gene="lplT"
                     /locus_tag="ACHY1N_002624"
     CDS             complement(31061..32254)
                     /gene="lplT"
                     /locus_tag="ACHY1N_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HFS4044918.1"
                     /translation="MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINP
                     FLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGET
                     RFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMIGIPVVPIGIGFGALFALAITALWI
                     WQRRH"
     gene            complement(32247..34406)
                     /gene="aas"
                     /locus_tag="ACHY1N_002625"
     CDS             complement(32247..34406)
                     /gene="aas"
                     /locus_tag="ACHY1N_002625"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008779 -
                     acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008922 - long-chain fatty acid
                     [acyl-carrier-protein] ligase activity [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HFS4044919.1"
                     /translation="MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGIL
                     LGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVI
                     FPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQI
                     TLHILPPTQVAMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFG
                     AGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAI
                     ARRRMPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLE
                     DLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILA
                     NVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPEL
                     AVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE"
     gene            34992..36023
                     /gene="galR"
                     /locus_tag="ACHY1N_002626"
     CDS             34992..36023
                     /gene="galR"
                     /locus_tag="ACHY1N_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HFS4044920.1"
                     /translation="MATIKDVARLAGVSVATVSRVINNSPKASEASRLAVHSAMESLS
                     YHPNANARALAQQTTETVGLIVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQMPGMVLINRILPGFENRCIALDD
                     RYGAWLATRHLIQQGHTRIGYLCSNHSISDAEDRLQGYYDALAESGIAANDRLVTFGE
                     PDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGIDVPGEISLIGFDDVL
                     VSRYVRPRLTTVRYPIVTMATQAAELALALADNRPLPEITNVFSPTLVRRHSVSTPSL
                     EASHHATSD"
     gene            complement(36030..37292)
                     /gene="lysA"
                     /locus_tag="ACHY1N_002627"
     CDS             complement(36030..37292)
                     /gene="lysA"
                     /locus_tag="ACHY1N_002627"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFS4044921.1"
                     /translation="MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALK
                     QFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTAD
                     VIDQATLERVSELQIPVNAGSVDMLDQLGLVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVIEFGQD
                     LQAISAGGGLSVPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQ
                     SGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVE
                     TVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALELL"
     gene            37414..38349
                     /gene="lysR"
                     /locus_tag="ACHY1N_002628"
     CDS             37414..38349
                     /gene="lysR"
                     /locus_tag="ACHY1N_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator LysR"
                     /protein_id="HFS4044922.1"
                     /translation="MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEK
                     VIGLKLFERVRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPQLLQPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTER
                     TELLSLDEVCVLPPGHPLAVKKVLTPDDFQGENYISLSRTDSYRQLLDQLFTEHQVKR
                     RMIVETHSAASVCAMVRAGVGVSVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLH
                     RPSSALVQAFSEHLQAGLPKLVTSLDAILSSATTA"
     gene            complement(38336..39028)
                     /gene="ygeA"
                     /locus_tag="ACHY1N_002629"
     CDS             complement(38336..39028)
                     /gene="ygeA"
                     /locus_tag="ACHY1N_002629"
                     /EC_number="5.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HFS4044923.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVD
                     FHEIDECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCTLPFL
                     HIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQI
                     IFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAA
                     IHAEDAVAFMLS"
     gene            complement(39157..40575)
                     /gene="araE"
                     /locus_tag="ACHY1N_002630"
     CDS             complement(39157..40575)
                     /gene="araE"
                     /locus_tag="ACHY1N_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-proton symporter AraE"
                     /protein_id="HFS4044924.1"
                     /translation="MVTINTESALTPRSLRDTRRMNMFVSVAAAVAGLLFGLDIGVIA
                     GALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLG
                     SIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLG
                     IVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVL
                     RMLRDTSEKAREELNEIRESLKLKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNI
                     IMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVM
                     ALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKC
                     RDFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFVGITFWLIPETK
                     NVTLEHIERKLMAGEKLRNIGV"
     gene            complement(40890..41651)
                     /gene="kduD"
                     /locus_tag="ACHY1N_002631"
     CDS             complement(40890..41651)
                     /gene="kduD"
                     /locus_tag="ACHY1N_002631"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HFS4044925.1"
                     /translation="MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVE
                     PTETIEQVTALGRRFLSLTADLRKIDGIPGLLDRAVAEFGHIDILVNNAGLIRREDAL
                     EFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRW
                     GLPSDLMGPIVFLASSASDYVNGYTIAVDGGWLAR"
     gene            complement(41681..42517)
                     /gene="kduI"
                     /locus_tag="ACHY1N_002632"
     CDS             complement(41681..42517)
                     /gene="kduI"
                     /locus_tag="ACHY1N_002632"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFS4044926.1"
                     /translation="MDVRQSIHSAHAKTLDTQGLRNEFLVEEVFVADEYTMVYSHIDR
                     IIVGGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRD
                     ALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFH
                     MMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKD
                     LR"
     gene            complement(42804..43985)
                     /locus_tag="ACHY1N_002633"
     CDS             complement(42804..43985)
                     /locus_tag="ACHY1N_002633"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708633.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HFS4044927.1"
                     /translation="MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVP
                     AYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAI
                     QCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
                     AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMIQSNGQTLVVDTDEQ
                     PRTDASAEGLARLNPSFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIR
                     AFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFAAQALSVGKMLEWDE
                     RRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERD
                     E"
     gene            44240..45469
                     /locus_tag="ACHY1N_002634"
     CDS             44240..45469
                     /locus_tag="ACHY1N_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4044928.1"
                     /translation="MSNIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGNLITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHMVIDLRIRMLVSLGVVLILNLIFLMGRHATIRVMGFLVFPL
                     IAYFLFLSIYLVGSWQPDLLTTQVEFNQNTLHQIWISIPVMVFAFSHTPIISTFAIDR
                     REKYGEHAMDKCKKIMKVAYLIICISVLFFVFSCLLSIPPSYIEAAKEEGVTILSALS
                     MLPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEVVKTTLQQVGVKKSRAFNRA
                     LSIMLVSLITFIVCCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPWRSIGN
                     LITLIVGILCVSVMFFS"
     gene            45929..46561
                     /locus_tag="ACHY1N_002635"
     CDS             45929..46561
                     /locus_tag="ACHY1N_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4044929.1"
                     /translation="MGLCSRYKSLTCNSCSMHCQIMPEESPRLQYCANSCFCMWPEES
                     SYFNRGVVEGILTKNHNARLSGYIFVDFSVSFLRLFLEKDWIDYLASTDMGIVLVSDR
                     NMQSLANYWRKHNSAISAVIYNDDGLDVANEKIRQLFIGRYLSFTRGNTLTQMEFTIM
                     GYMVSGYNPYQIAEVLDMDIRSIYAYKQRIEKRMGGKINELFIRSHSVQH"
BASE COUNT        11574 a        12542 c        11526 g        11097 t
ORIGIN      
        1 aaattctaat ctcactactc gttggtatta atttcaataa aaggaaagat aaatcctccg
       61 atggacgact taacccaacg ctactacgaa gccgaaatgc gctacctgcg tgaagcgggg
      121 aaagaatttg cgcaggctta ccccgaccgc gccgcgatgc tcaatcttga taaacccggc
      181 gcacgcgatc cctatgtgga acgcctgttc gaaggctttg cttttttaat gggcagcctg
      241 cgcgagaagc tggacgacga tctgccggag ctgactgaag ggctggtcag cctgctgtgg
      301 cctcactacc tgcgaactat cccgtcactt tccgtggttg aactgtcgac agatcaccgg
      361 cagatgaagc agagcgaaac gctgagcgat tttcaggtat tgtcgcgccc tgttggcgag
      421 cgcagaaccc gctgtttcta cagcgccacg cgggatatca cgctgcatcc gctggcgttg
      481 ccggacgtgt cattgcaata tgaaccggac ggacgttcgg ttattcgtct gcgctttgaa
      541 tgcggcccgc tggtcggtga ctggtcacag atcgatttat cccgcctgcc gttctatctc
      601 aatgccgaca gtccggtggc ctgtgcgctg caccgggctt taacgcttgg tacgcagcag
      661 ttctggttgc gtctgccggg gcaggatcgc cggacgcttg acgcacactt ttccccgttg
      721 ggctttgagg ataatgacag gctctggcca aaaggcgagt cggcgttcag cggctaccag
      781 ttgctgctgg agtatttcac cttccgcgag aagtttatgt ttgtggcact caacgggctt
      841 gagctggttg catggccgga ggggataacc ggctttgaga ttgacgtggt gctgaacgag
      901 aactggcctc acgacctgcc gtttgacagc gataatatcc gtctgcactg cgtgccggtc
      961 atcaatctgt tcccgctcga agccgatccg ttacaccttt cgccactgga aaacgaattt
     1021 ctgctacgcc cgatgcgcat tcaggacggg cataccgaga tttattccgt cgacaacatt
     1081 atttcttcgc gccataccgg cagtcaggcg tatgtcccct tctccagctt tcgtcaccgg
     1141 ggcgggatgc tgcgccacga tgcgccggaa cgctattacc acacgcgggt aaagcgcggc
     1201 ccttccggtc tgcatgacac ctggctgatt ctgggcggtg atgcgtttga tgctgaccgg
     1261 atgctggagg atgaaacgct ctctttaagc ctgaccggta ctaacgggca tcttccccgt
     1321 aaggctttac agagcacgct gctcgatagg ccagttcatg cctcacagaa cgtcctgcgg
     1381 gtgcgcaacc tgtgcgcccc aacgcagccc tgctatcccc cggcgcgtga ccgcttccac
     1441 tggcgggtgc tcagccacct tggttctaac tttttatcga tgatggataa cgccgaaatt
     1501 ctgcgcggaa cgctggcgct gtacgactgg accgaaagcg agatgaaccg ccgtcgtctg
     1561 gaggcgattg tcgacgttca gcacagcctg atacagcgtt ttgaaagagg ctttctgctg
     1621 cgtggcgtgg atattcaggt gacgctggac agtaacggct ttgccggaga aggtgatatc
     1681 acgctgtttg gtgaactgct gcaccgcttt ttcgcactgt atgccgatat ccacttattc
     1741 actcaactga ccttaattct gcaacctaca ggaaagtgcc tgcaatggac agagcatcac
     1801 agccagcgcg taccgggctg accgaccggc tggccccgga tattgcgcgg atcaattttt
     1861 accgtttttg ccagtttctg gaacagagcc agcagaacgc gccgctgggc agtaccgaca
     1921 accccgccac cgatgcggtg cgctttcgtc cccatcccgg aatgggcttt ccggtcagcg
     1981 agttaaagaa cgttgaacgt gacgcgggca atcccaacgt gccacccacg gtgcgcacca
     2041 cctttctcgg cctgtacggc gtggattcgc cgctgccaac cgcctatctg gactacatta
     2101 cccagcgtca tgacggacat gacgcagtga tggcgtttct cgatattttt aaccatcgct
     2161 ttatcaccca gtattaccgc atctggcgca aatataacta cccggcgtcg tttgaagcag
     2221 gtgctatgga tgacatttcc cgttgtctgc tgggactcat cgggctgggt attcccggca
     2281 gcgagaacca tatcgccacg ccggtatccc gttttctggc cctgctcagc gtgatgcgcc
     2341 tgccgacgcg cacggcggaa ggcgtcacgg cactggtggg actgcttgcc ccgctgacga
     2401 aagcgacggt ggtgcctcac gatccgcagc ctgttattct cccggcccct gcgggtctgt
     2461 caaaaaattc acgcatcagc ctgaaaacgc gaacgctgct ggggcgtacc ggcaccgacg
     2521 tcaacagcca gttgctgctg aaactgtata ccgaagatgc cgcagaagca cgtggctggc
     2581 tacctggcgg gcagctgcac agcgatttgc tggtgctgct gcgcgtttat ctgggctggc
     2641 gctgtcaggc ccgtctgcaa ctgacgctgc ccgtcagcct gttgcctgct gcccggctgg
     2701 gaaaacagcg cgtacagatt agccgtaccg gcatccttcg cgcctccttt gccgcgcccg
     2761 cgaccggaac agtgacggtc agtctggggc gttatcaggg attaataccc gctttatcca
     2821 ttcgtaacag ggagagtatg actcatgttt cctattcgtt ttaaacgtcc ggcgctgctc
     2881 tgtatggcga tgctgacggt tgttctgagc ggctgcgggc tgattcagaa agtggtggat
     2941 gaatcgaaaa gcgtggcctc agccgttttc tacaagcaaa tcaaaatact gcatctcgat
     3001 ttcttctccc gaagtgccct gaatacggat gcggaagata cgccgctttc cacgatggtg
     3061 catgtctggc aactgaaaac ccgcgaagat tttgacaagg cggattatga caccctgttt
     3121 atgcaggaag agaagacgct ggagaaggac gtactggcaa aacacaccgt ctgggtaaaa
     3181 ccggaaggca cggcatccct gaatgtgccg ctggataaag agacgcagtt tgtcgccatt
     3241 attgggcagt tttatcaccc tgatgaaaaa agcgacagct ggcgtctggt gatcaaaagg
     3301 gacgaactgg aggccgacaa gccgcgctcg attgaactga tgagaagcga cctgcgactg
     3361 ctgcctctca aggataaata accgatgtcg acaccttcct tatatgaaat gctgacgttc
     3421 agtttcagcg gcgagttacc actggaacag gtcagcgagc gggatcagct tatcctttcc
     3481 gtgatggaca atatgcaacg cattatcaac tgtcgggcag gcacactggc gcatttgccg
     3541 gattacggtc tgccggatct cagtctgatc catcagggta tggttgcggg tattcatggc
     3601 ctgatgcgtc agattgaaga aacgctgctg cgttatgaac cacgcctgag tcagatacag
     3661 gtggagttac tcccccagcc ccgtccgggg tatcttaatt acctgatcca cgcgcagctt
     3721 cccgataccg gctggatacg ctttgatggc gtgttttctc cggaaggacg aattgttctg
     3781 cgtcatctca aacagcagga gcgggcgtac tgatggcaag taacgcgaat tttatcagcc
     3841 agttcgtcat gggcggcgat ccctgtactt ataaggaatc cggtgaacta caggctgaaa
     3901 tgagtaaact gactcacccg gcccgacctg atgtggactg gcgtcgggtg gaaaaactca
     3961 gcctcgcgct gttccggcaa aatggcgtgg aattacagac gcaggtctgt tacgtactgg
     4021 cgataaccag acggcagggg ctggcaggga tggcagacgg actcggttca ctggacatac
     4081 tgctccagcg ctgggctgac ttctggccgg tacaggtaca ttccagaata tcactgctca
     4141 gttgggtcac agaaaaaatg cagcaggcac tgagaacgct ggatattcag tatcaggatc
     4201 tgccgcagat ttaccgttgt gtacagcatc tttccgccat cgaaaccacg ctgcaacagt
     4261 gtgaactgtg gcatatgacg aaactggatg tgctggccgg gcagtttcgt aatacggcgc
     4321 tacgtctgga gcggctggca ccacagggag cggaaaccac tatcactccc cctgaattac
     4381 cccgccggga aatgaagcaa ccagaaaagt cagaagaaag tccacagccg gtttttgcaa
     4441 ccagacccgc tcagcaaaac gataaggatg ccagtccatc cgcgccatcc cctgaaatct
     4501 cctggcagcg gacatggccg atatttatgg ccggaatggt tgtgatggcc tgtctcggcg
     4561 gaacaggatt atggggctgg tcgcagctta atcagccgga cgcactaatc cagcgaatac
     4621 aactgtctgt catgccatta ccgcagtcgc tggagagcgg cgagctggca aagctggatg
     4681 taaaggataa ggcgctgctg gctcaggaca gaacaattgc ggcaagtcag atgcaactgg
     4741 agcagttaaa caaattgcct gcccgctggc cactggagca gggatatcgc cagctacgcc
     4801 agcttgatgc cctgtggccg gataatcctc aggtcagagc gctgaacgcg cagtggcgta
     4861 aacagcggga gctgagcgcc ctgtccacag aggcattgaa tggctacgca caggcgcaga
     4921 gccagctaca gcgcctgtcg gcgcagctgg atgcactgga tgagcgtaag gggagatatc
     4981 tgaccggttc ggaactaaaa acggcggtgt acggcatccg gcagtcgtta aaggagccgc
     5041 cgctggaaga actgcttcgg caactggaag agcaaaaaca gaccggagag gtttcgccga
     5101 cgctgttgac gcaaattgat acccggttaa atcagttgct gaatcgctat gtaattttac
     5161 tggatacgaa ggtggaacaa agtcagtaaa cgtcggggga tttatgcacc aataagggat
     5221 atgtgacctt gccatttttt aaaaggagtc tttgtgtaca aaaaagagag gaacaggcca
     5281 ttcgaaacgc gtgaagaggt tctggcatat cataagcggg aaaaaatacc ctgtctggag
     5341 tgtggcaagt tgctcatttt tttaccgcgc catatctggt ttgtgcatgg aatacgcgct
     5401 gacgaatatc gtgtaaaatg gaacataccg aagcacatcg cactggcagg gatttcatat
     5461 ctggagaaac aaagtgaata tatgaaggcg agaatagcaa agggaaagct ggatcccgca
     5521 gaacaaatag ccatgatgag aataaaggga aggcaactaa agtcagatcc tgactggcgt
     5581 aatcgctccg gttctatatt gaagaaacaa tatgcccgac gagatatcct taaaaacagg
     5641 gtatgggaaa gatctcccag cataaaaagt gtctctgtgg agttgaaaac agaagctata
     5701 aggcgaatga aaaacaggaa ggtcgtcggg gaaaaagtcc aggatattgc cgatgacctg
     5761 aacgtatcta tcagcagatt gtatcactgg ctaaagatgt aggcgctcat gtgctctcaa
     5821 tgccttcaat aaagccgcta tgcgcgaacc ggcacatctg gtagactgtt ctcagtgagt
     5881 caagcaaact gcctactttt ctaactttta atcatgaata accagcgcct tgagtatagc
     5941 tggttcgaat atactcgttg attcacatca gataatgagt gtataattcg gtagatagct
     6001 tgggttcggg aacagtgaat gccttaagtt tcaaaaggtt agattaacct cttgactgtg
     6061 gcccccgcaa ccaattattg aacaccctaa cgggtgtttt tttgtttctg ctctcccata
     6121 aaaaaagcgc cattcagcgc ctttttatca tccccttctc gccagcgtcg ccccatcggc
     6181 aaaatacgct ttaattcccg caagaataga ctccgcaact tcctgctgga aagtcgccgt
     6241 tttcagttta cgctcttcct caacgttact gataaacgcc gtttcgacca gaatggaggg
     6301 aatatctggt gcctttagta cggcaaaccc ggcctgttca acttgatttt tatgcagctt
     6361 gttgatttta ccgagcttat tcagtaccgc tttaccaaac ttcaggctgt cggcaatggt
     6421 cagcgactgc accatatcga acatggtgtg gtcgacatag cggtcaccgc ttttgctcac
     6481 gccaccaatc aagtccgagg cgttctgggt ttgtgccaga tattttgccg cagtactggt
     6541 tgcacctttg gttgagagcg caaacacaga ggaaccgctc ggctgacgac tggtaaaggc
     6601 gtcggcatgg atagagacaa acaggtcagc acgctgtttc tgggcttttg ctacgcgcac
     6661 ttgcaacgga atgaagatgt cttcattgcg cgtcatgtac accttcatat tgccctcttt
     6721 ctcgatcaga gagcgcaaac ggcgagctat ttgcaatacc acgtcttttt cgcgcgtttt
     6781 gtatttcccc accgcaccgg agtcttcgcc accgtggcca gggtcaagca taatgacaat
     6841 cggacgatcg cgccctgctt tacctggttg tggaccactt tgcgctggcg gcacctgctt
     6901 ttcgaggtcg cctttgttgt aatcctccag cagcgccagc agcgggtcct gcatatcctg
     6961 tgcattggcc ggatagaggt ccatcaccag acgctcttta aacccggcga ccggcgcaag
     7021 ggcaaacagc tgcggtttta cgttttgctt taattcaaaa accatccgta cggtttgcgg
     7081 gtcaaattgc ccgacgcgcg ccgacttgat gaacgggtcg tctgcacgaa tttgtgccgc
     7141 catccccttg agtaccgagt tcaggtttac atcttcgata tccaccacca cgcgttccgg
     7201 gttactcaac gcgaactgct tatatttcag ctgacgattt gattctaccg tcacacgggt
     7261 gtagctggac gcaggccaga cgcgcaccgc cacgacctgg ctgaccgcag ccagactgac
     7321 ctgacttacg ctcaatagcc acatggcacc cgcgccttgc agtaaacgac gacggctgat
     7381 tgcagtgttg gatcctgaca tgcctctccc gagcaaaaga aatctaagct gtgtaacaag
     7441 taaacgacta atttgaccgg aaactttagc gaaagacgca taatctgtca tctaataaac
     7501 ggtaaacatt ctttttatat tcacggcatt actgataaaa aagtcgctct cgcataaaat
     7561 ttacacttgc accctgcgaa aaaacagaat aaaaatacac taatttcgaa taatcatgca
     7621 aagaggtgtg ccgtggtaaa ggaacgtaaa accgagttgg tcgagggatt ccgccattcg
     7681 gttccctata tcaataccca ccggggaaaa acgtttgtca tcatgctcgg cggtgaagcc
     7741 attgagcatg agaatttctc cagtatcgtt aatgatatcg ggttattgca cagcctcggc
     7801 atccgtctgg tggtggtcta tggcgcacgt ccgcagatcg acgcaaatct ggctgcgcat
     7861 caccacgaac cgctgtatca caagaatata cgtgtgaccg acgccaaaac actggaactg
     7921 gtgaagcagg ctgcgggaac attgcaactg gatattactg ctcgcctgtc gatgagtctc
     7981 aataacacgc cgctgcaggg cgcgcatatc aacgtcgtca gtggcaattt tattattgcc
     8041 cagccgctgg gcgtcgatga cggcgtggat tactgccata gcgggcgtat ccggcggatt
     8101 gatgaagacg cgatccatcg tcaactggac agcggtgcaa tagtgctaat ggggccggtc
     8161 gctgtttcag tcactggcga gagctttaat ctgacctcgg aagagattgc cactcaacta
     8221 gccatcaaac tgaaagctga aaagatgatt ggtttttgct cttcccaggg cgttactaat
     8281 gacgacggtg atattgtctc cgaacttttc cctaacgaag cgcaagcacg ggtagaagcc
     8341 caggaagaga aaggcgatta caactccggt acggtgcgct ttttgcgtgg cgcagtgaaa
     8401 gcctgccgca gcggcgtgcg tcgctgtcat ttaatcagtt atcaggaaga tggcgcgctg
     8461 ttgcaagagt tgttctcacg cgacggtatc ggtacgcaga ttgtgatgga aagcgctgag
     8521 cagattcgtc gcgcaacaat caacgatatt ggcggtattc tggagttgat tcgcccgctg
     8581 gagcagcaag gtattctggt gcgccgttct cgcgagcagc tggagatgga aatcgacaaa
     8641 ttcaccatta ttcagcgcga taacacgact attgcctgcg ccgcgctcta tccgttcccg
     8701 gaagagaaga ttggggaaat ggcctgtgtg gcagttcacc cggattaccg cagctcatca
     8761 cggggcgagg ttctgctgga acgcattgcc gctcaggcga agcagagcgg cttaagcaaa
     8821 ttgtttgtgc tgaccacgcg cagtattcac tggttccagg aacgtggatt taccccggtg
     8881 gatattgatt tactgcccga gagcaaaaag cagttgtaca actaccagcg taaatccaaa
     8941 gtgttgatgg cggatttagg gtaagcgatg aaaattgtcg gatgcgacat gcgtaacact
     9001 cgtgcgtcgc atccggcaat tacgtttatt cccgcgaact aaacaacgcc gccagaccac
     9061 tgcgccgctc agtacgagtg gcgattgccg cacttaatat acgctcatcg gcatacagcg
     9121 acagacggcg acgcgcgcgg gtcaccgcgg tgtataccag ctctcgcgtt actaccggcg
     9181 tgcgttggct cggtaaaatc aacgccgcat ggtcgaactc cgatccctgc gatttatgta
     9241 ccgtcatcgc ccacgtagtt tcgtgctctg gcaagcgact cggttgcaca gacttaatat
     9301 tgccgtccgg catcgcaaac cagacgcgcg tcccctgccc gcgatccagc gcaataccga
     9361 tatcgccatt aaacaaccca agcgcgctgt cattacgggc aatcatcacc ggtcgacctt
     9421 cgtaccaacg agagtgcgga tgacgatgaa ttttgcgctt ctgttgcata aactgctcaa
     9481 ttcgctcatt cagtccagcc acgccaaacg gcccttcccg cagggcgcac aaaagttggt
     9541 actcattgaa cgcctgaatg attaaatccg gctcagcacg cgcttgcagc agatccagat
     9601 aacgtccata acccgcaaga gcttcctcaa gcatcgcaat ataatcttcg ccgctctgta
     9661 aaagtcgttt ttcgatatca gtaaaatcct gctgaaaaac ggttttcact gccgttttat
     9721 caccacggtt gatcgccgca gctaactgac caatgccaga atcgctgccg aaacgatagc
     9781 ttttttgcag caggcagaga ctgtcgcgca aagatgccgc ttctgtgccg gttcctgccg
     9841 gaacgtgagt ccccgtcagg cggcttagct gcccggcacg ctcggcggta aagccggcat
     9901 tggcataagc gcagatatcg cccagcacag ccccagcctc aaccgaggcc agttgatcac
     9961 gatcgccgag aaagatcact cgcgcatgat cgggcaaggc gtcgatcagt ctcgacatca
    10021 taggcagatc gatcattgac gcttcatcta ccaccagcac atcaagatgc agcgggttac
    10081 cggcatgatg acgtaaacgc tggctacccg gctgcgcacc cagcaatcgg tgcaaagtac
    10141 tggcatcttc cggaatgcgt ttcttttgtt catcggtcag cggtaactgt cgcaaagcct
    10201 tgccgagaga ttcggttaag cgcgcggcag ctttacccgt tggtgcagcc agacggatac
    10261 ggcagcgttc gccgtcggcc atttgaatta acgctgccag taacttcgcc acggtggtcg
    10321 ttttaccggt gcctgggccg ccggaaatca ccgagatccg ccgcgtcagc gccactgccg
    10381 ctgcaacttt ttgccagtta atttcatcgc ttactggaaa aagtttgtcc agggtttgcg
    10441 ccagtagagc ttcatcaacc tcaatggcat gattcacctc attgaagaag cgcgctaccg
    10501 tccgctcgtt acaccacatg cgattcaaat aaagacgatc gccacagagg atcatcggcg
    10561 tgggttcatc tcccctgctg accgcttgag aagccagcaa gcattcttcc caattttgta
    10621 gctcaccgat ttcactgaca caggtcgcca acagcggatg cgacgcctcg ttattttcca
    10681 gtcgtgaaag cggcaaacag acgtgtccct ctccggcatc atgacttaac agtgccgccg
    10741 cgagggtgac ggcaggatgt tcatctcccg ccacggtcag ggcaaattgc acatccagcg
    10801 ggcgtagctg tttgtgctcc acagcttcca gtaattgctt ttgcaatttc attacgcctc
    10861 ctccagggtc ataccggcaa acatctcatc catcaggtca atcaacccgg cgttgggtcg
    10921 ggttgtgtaa atcccttgtt gcggatgttc tttatcaaca ccacgcagga acagataaat
    10981 aacgccgcca aagtggcgct catagtcgta atcagcaatg cgatggcgca gataacgatg
    11041 cagcgccagg gtataaagct gatattgcag atcatagcgg tgtgcctgca tcgccgctgc
    11101 catagcctgt tgggtgtaag ccgaactgtc ttcacccagc cagttggatt tatagtcgag
    11161 caggtaataa cgcccttcgt ggcggaatac caggtcgata aagcctttta acatgccgcg
    11221 tacctgcatg aactccagcg gcgggcagcc agcggatagc ggatcaaact ggcgaattag
    11281 tgcatcaagc tggctggcga tgagcggttc actaatcggc aggtaaaact ccatctccac
    11341 ctgtttatcg cggtcggaaa gctgattcag gctaacaccc gtttcattga gaggtgcctg
    11401 gaggacagcc gtgatccact cggtcaacac tggttcccac tgcgattcaa agccgccgag
    11461 ttccagtttt tcctgtaccc agttcgggtc aaccggctgg gtaaaatcga ggtcttcaaa
    11521 caaactgtgc aagaatgtcc ctggtgacgc accgcgcggg aactgatgcg gtgttaacgt
    11581 cggttcttca acgacgctga ccacgcctgc ggcatcaaca tccagccgtg gcatcagatc
    11641 ctgagcgata ccgtgaccac gctgctgcaa accggagtag ctggtgacac gccagttatc
    11701 gccgggcaat cgttgtagcg tcctcgcatt cagttctgca gttaaagcat cattaacctg
    11761 ccagggctgt ttatcacccg tttgtgccgt ttgccaggca atatcatcat cgcataacgc
    11821 ttcaatacag gtgcgaagcc ctgccgcatc ttgcggttcc cctttttgca gcaaacgccc
    11881 gagcgcactt tggtggacgt cggtgtcacc ttttttatcg ccacgacggc gcaccagcgg
    11941 tgcaacgccg agactgcaat gccaaaccga acgtgtcagc gccacgtaaa gcaaacgcag
    12001 atcttccgcc agacgttcgg cctccgcgag gtcgacgctt tctggcgcag cattaagatc
    12061 cagaactgcc tcaaacgagt ggcgatcgtg ataaaacgcc tgatcctgga cgcggaaatt
    12121 ggtgataaac ggcagccaga ccaatggata ttccagccct ttcgatttgt ggatcgtgac
    12181 aatctgcacc agatgtttat cactttcgag acgcatttgt tggctggagg cattactgtc
    12241 tggctcgagg atatgttgcg ataaccagcg taccagcgca tgttcacttt ccagctgcgt
    12301 tccggcttct tgtagcagtt cgctgatatg caagatatcg gtaagtcgcc gctcaccgcc
    12361 tgccgttgcc agcaagtttt ctgcaatgtt acgcgccgac atcagcgccc gcagcatcgg
    12421 cataacgcca cgtttgcgcc agatttgccg ataaccatcg aactcttcga ccaccgcgtc
    12481 ccacgcatgt tcgtcattat tcagcgtttc aatatccagc gcattcagcc ccatcattga
    12541 cgttgccagc gcactgcgca gggtgttctc acgttcgggc gtcatcaccg cctgcaacaa
    12601 ccaaagcatt tcctgcgctt ccagagtttc aaaaacactg tcgcggttcg aaaggtaaac
    12661 ggaagggatt tccagcaacg ttaaggcatc gcgcacctgg gcggcctcct ggcggctgcg
    12721 caccagcaca ctgatgtccg aagcacgcac cggacgcgcg tcgtcgccgt tcatcagcaa
    12781 cgcttcgccc cgctgtccgg cttgtagcca gtcgcggatt tgcgcagcac atacctgcgc
    12841 catggtactt tgataatcgc caacgccgca gctttcgcct tccatcagcc acattttcat
    12901 cgcaggctgc gtttcacctt taaatacaaa acgtaacgcc tgatttttcc cgactgattt
    12961 cactggaata aacggtattt cgcgaaacat gaacgcgtca tcagtctggc tgaaaagctt
    13021 attcacgctg ttcaccattc ctggtgcgga acgccagttg gtgtctaaag tgtagtgggc
    13081 gtgaacttcg ctacgcgcct tcatataagt gaagatatcc gcaccccgga atgcatatat
    13141 ggcctgcttc gggtcgccaa tcagcaacaa tgcggtttcc ggctgatggt gccagatacg
    13201 gcgaaaaatt cggtactgct gggggtcggt atcctgaaat tcatcgatca ttgccaccgg
    13261 gaatcgcgta cggatcgccg ctgccaacac ctcaccgctt tcgctacgca gcgcggaatc
    13321 gagccgactt aacatgtcat caaaacccaa ttcgccacgg cggcgttttt cacgcgctac
    13381 tgtttcgcgg atctcagcca atgcgcgggt gatcaccaga tcgcggatcg acaatggttc
    13441 tgcaagcagt tgatcgatcg cctcaaacag tggatgtcgc ggggtttccc ccccggcttt
    13501 cgtgcgatct tctaagaaac gctgggagaa tttttccagc gactccggca actgataact
    13561 gttggtctct tcttctgccc aggcgctgat cttgtcgatc catttagcct gattgctacg
    13621 gttaaacttg cgtcgatcaa taccagaaga ttcgatcagc gcatccagtt cacccactgc
    13681 gtcgcgccac tgctgtttta ccgtagcaat acgcgccaca atttgcgcgt ggcgggaagc
    13741 cagcgtttca tcatcgggcg gcggtgcttt gataaccggc gcttcgcctt gcagataacg
    13801 attaatatcg cgcagcaacg cctgcggccc tttccaggtt tcaaagacga cctgggctat
    13861 ttcacgcggc agcgggtagc agtggcgacg ccagaaatcg gcgcaggcct ggtaacgtag
    13921 cagagactca tcttcaatca gctgctgctc aaacagcatg ccggattcaa aggcattcag
    13981 gttgagcatg cgctggcaaa aaccgtgaat agtaaagact gccgcttcat ccatctgccg
    14041 ttcggctaac aacaaccact gcgcggcttg cgctttatcg tcgatctctt ccagcagacg
    14101 ttcgtacagt ggattgtcgg tggtttcacg cagacaggcg atgcgcaact catggatatt
    14161 gctacggata cgaccacgca attctgccgt ggcagcctcg gtaaaggtga ccaccagcag
    14221 ttcttcaacg gtcagcgggc ggggaaaggc ggcggaaccg cctagtccaa gtaacaggcg
    14281 caaatagagc gccgcaatcg taaaggtttt gcctgtgccg gcagaggctt caatcaggcg
    14341 ctcaccctgt aagggcaagc gcaaaggatc tagtgtctcg gcgacatcac tcattctttt
    14401 cactcatcag gggcattgtt tgctgcaacg cgctgacgtt ctcccacact ttccagcctt
    14461 cagggtgtac atattcggct ttcccattct ggctgccgga aatctgcgac aggatagcca
    14521 tgccttgcgg ctcgactacc gcctgatgga agaaatcggc cagtttttgc ggcgtcagca
    14581 gtttaatctg ggccacgatt ttatcacgcg aatcgaagcg catattgccg cgatcgaaat
    14641 ctttacttaa cttcgatgct tcttcgccga gcgtttgcgg tgcctgcagc atctgggtaa
    14701 ttaccgcctg ctggatttgc gcaaactcat ctggcttcat cgctcgcaat tttgcctctg
    14761 cagttgggaa aaacgccttg taacgctccc acaagaatga aggctgttta tcattgcttt
    14821 gcaaaaggaa gcccatgccc cactgacgcc ccacgctcat tggaaacgca aacacggcat
    14881 agcccaattg ttcttcggta cgcaactgat tgtagaacca cggctgtacg atctgcccca
    14941 acagagagct ataggctgag ctggtgtatt catcgtagcc agtcggtaca aataccgctg
    15001 ccagtgcgga gtcggtgctg ttaccggctt tttcaaagat gacggattgt tttttatcga
    15061 ccactacatc tttgtttcga caccactctg aaccatcagc gcccaactgt ttttgcacat
    15121 cgcgtgccag cgttgttgcc tgggcttcgg tcatgttgcc aataaccata aactctggtc
    15181 gagcccctga ttttaaggcg tcgcgatagg ccagcacctc tttcaacgta atggagggca
    15241 aaattttgcg ccgttcatct cgcgagaagt acggcacttg cgagagcatc tgcgcgggca
    15301 taatcgcctg ctcgaacgct ttgccctttt ctgcggaatc catcatctgg ttataccagg
    15361 acttcgcctg ctcaagctga tcttccgtgg cggtatagct aaagtagcct tccagcaatg
    15421 cctggaacag ctgcggcaga cgctgggtgt aaccattagc attaaccata aggccgttgt
    15481 tagcgttggt ggaaaaactt atgccaccaa ccgacgcctg gttgcttaac tgatcaagcg
    15541 ccagccctgc gagataatca ttgagcgcaa acatcacctg attgcgggcg ctgtccatgg
    15601 ctttcggatt acgcaaaatc aggctgacat cggcttttgg ctcgctggca aaataacggc
    15661 ttggcgcata caccacgcgc agattcgact catcaacaat cagctctgga tggtcatatt
    15721 tcttgtctga cttaatcagc gagaaatcgt caggaatata agggttaagc tctggcaaag
    15781 agagcgcaat gtcggcggct tttttctgcc agtcggcgaa agtttgtgcg ctgattttat
    15841 cgacctgata cggcgcatcg acaaagtaag ccgttttgtt gtgcggctct ttcgggctga
    15901 tataccagat acgcgcattc tgcggcgtca tcatcgccag acgttccttt actgctttag
    15961 catcgtaccg atcggcaata ttgactgcat ccagcgtatg ctcaacagga acgcgaatca
    16021 tggtatctgc cagccattcg acgtaatcca tatcacgggt gattgacgga taacggaagt
    16081 cgatatccag cacattcgcc agttcatcga agtattgttt atcgatccct ttttcacgta
    16141 acaaattgag gtagctaaaa atagccgcca caacctgatc gcgattcgcc agacctttat
    16201 cggttaaaga cgcagagatc gctaatacgc cgctgttgcc gttgacgata ggatcggagt
    16261 tggcgctaat gccctcaact aatccctgct tttgcagcca gtcggaaagt gtacctgggc
    16321 tgcgattacc aatcagatag gtaatcaatt catcggtttt gctacggaat ttcgccgagt
    16381 tgttatcaat acgaaactct acgcgcaaca ctttacgcgg cagcgccggg acgtaatgaa
    16441 tgataatgcc cttttgcgcg tcggtgacta ccggcacggt gatttccggt tttttgctct
    16501 ctttgttcgg cacgcgacca aaggtgtccg ccgccatttt tgccaactcc ggcagcggtt
    16561 tattgctgta aataaccgcc ttcatcagat tggcggaata gtacttctcg tggaaatctt
    16621 tcagcgcctg ctgcaccgga ttaccaggtt tgtcgcttaa agtttcgagg ttaccaccag
    16681 aaaactttga accggggtgt gccgggttaa tggtttctgc gctgacctgt gccatgcgca
    16741 tcccgtcacg cgtacgcgcc atggttaatt cagcgttcac tgcattacgc tcacgttcgg
    16801 cgtatttctt gtcgagcaag ggttctgcaa tagcatcagc caggcggtct accgcaccag
    16861 gcaaggcgtc gttctcaact tccagataga aagccgtgcg atacggcgca gtgctggcat
    16921 tgtgactacc gccgtgcatt ttgagatatt cggccagact gtcagcctgc gggtactttt
    16981 tcgaccccat cagactcata tgttcaaggt aatgtgccag cccctggtac gcctcgggat
    17041 cttccagcga cccaacgggc accaccagcg ccgagagcga tttaactgcc tgcggatcag
    17101 aaaccagcaa gaccaccata ccgttatcca gacgtatagc ctgatactgg cggttatctt
    17161 tatcactttt acggatggtt tcctgaatcg gctgccatcc cgtttctgcc tgacttaagg
    17221 gtgcccaaag ggcaactaac aacaataatg ctttgaacca ggtgctgcgg ggcattcacg
    17281 gacctcataa tcaacttaat tttctgtcca gattcaacac gttaacgcaa atcatctgcc
    17341 agaatttaat cttgtgctgc acgagtcagc ctatgtttat ataaccatca gtccgtgact
    17401 ggtgcgcatc ataaagcaag cggatagatt gcgcaatttt tatacagcac tcatgactga
    17461 ttaaagcgaa acagcggtaa caggaaacgt tgcgactgtt caacgatggc ctccattgtc
    17521 tctggtgtta attgccgcca gagccgttga taccagatat catcaccttc gccacgcacc
    17581 atcatgttgc cttcgtaagc ctgcaggaat ttcgtacggg ctttttgcaa cgtggaatcg
    17641 tcatccagca tggcatcgtt ttgcgcgtca taacaggttt ttagccacgc gccgccactt
    17701 tcaggtaaca ccagcaatgg cgcggacatc ccttcacgat acccctcaat cagttgtgag
    17761 aggtaatgca aagcctgttc ggctgcaagc ggcggaaaac gccactcgcc gtctttgcgt
    17821 agaaaaaggc gactttcacc attaccaccg ctggcacagt agacaaggtg ttccagccaa
    17881 agttgcattc cctgcgccac acttaataaa gagggacgcc agcgcaacaa gccatccggc
    17941 tgcacctgcg gcaaccagcc agttatctgc acaccgttgc aggcgagatc aatttccata
    18001 ctctgccccg gctggcgaca ggcaatgact ctgtcggcaa gctgctgcat ctcatggcac
    18061 tgtgtttccc agaaaatttc accaaaagcg ccatacggta aatcccctgc cgcccggaag
    18121 cggcggaaca agcgttcggc atcatcctgc tcaaccagtg cattcaataa ctgctgattg
    18181 atttgataac gactaagccc ttcaagaata aatggctcgg tgtcggggat ttcgctgtct
    18241 tcagtacgga agttcacctg caaacgcatc tggaagaacg cccgcaccgg atgtgcccag
    18301 aatcgttgta gcgtttccag cggcacggtt tccggtaagg taaacggcag cggctgaaca
    18361 aattcagaat gtgctttacc agcctggctg gccgcaggta gccattcacg agcatagctt
    18421 tgtcgttcgc ctggctggta gttttgtgga tcaaacggca tccgggtatg gaggcaagta
    18481 agatgcgctt ttacccttgc ctcgctttca tcacagttga gcgcttcatc gcccggtaga
    18541 taatgacttt gcccgatgta gtcgatcagt tcctgcacca gtaccgacgg gaaacgttca
    18601 ctgttatcct gaatggagcg cccgatatag ctgatataaa gtttttgttg cgcggaaatt
    18661 aacgcttcca ggaacagata gcggtcatca tcgcgacggc tacggtcgcc acgcttcggt
    18721 ttctggctca tcaggtcaaa gcccaatggc gcaagctgac gtggataaac gccgtcgttc
    18781 attcccagca ggcaaaccac tttgaacgga attgaacgca ttggcatcag agtacaaatg
    18841 ttaaccggtc cggcgagaaa acgctggctg atacgttctt gatccagacg ctgcgccagt
    18901 tcatcacgca atagtgacag cggcaccgcg tcgccatact gcgcacctaa accttcggcg
    18961 ataatcgcct gccattgttg ttcgatcagc gtcatcgccg cttcggtttc cgcatccggc
    19021 aggaagaagg cgttgagcat atcgcgacaa accggcaacc actcttctag cggacgctcc
    19081 tgtgccagcc cgcgacgcca gatgtttagc tgcattagca gtgaagccag atgccccacc
    19141 agttctgcaa ttaagccgct cgattcatca taaggtagaa ccgattgcca ctcgccctgc
    19201 gcgctctcca tcgcgtagcc cagcaacata cgcgtcaggc caaatcgcca ggtgtgttgt
    19261 ccggtggcgg ggagttccag ctcgcgaacg ttgtcgtcat ctatccccca acgaatgccg
    19321 gattcgttga cccactggcg taaataacgc agcccttctt cggtgatgtc aaaccgcgcc
    19381 gccagcaccg gcacatccag taatgccagc acgtcttccg acacaaagcg gctgtctggc
    19441 aacgataaca ggctgataaa cgcttccagt accggatgcg actgccgcgc ccgacggtcg
    19501 gaaatggcgt aaggcaggta acgatccgca ggtgcgctac caaacacagc ctgaataaac
    19561 ggactgtagc tgtcgatatc agccaccatc acgatgatgt cgcgcggagt aagtgtcggg
    19621 tcttcttcca gcatcgccag caggcgatcg tgcaaaactt caacttcacg ctgcgggcta
    19681 tggcaaacgt ggaaggtgat actgctatcc agtggatcaa gcgggcgttt gttatcgcta
    19741 cgggaaaact cttcgatgtt cacaccagca acggcacggt tttccagttc cagaatgtca
    19801 gactgaatgt tatgcagcag gttatctggc gtgacatcga caaaggcgtc cagctcctgg
    19861 ctgctctcca ggtcagaaag gagataaatg tagtcgcgcc caagcttacc ccatgaagcc
    19921 agcagcgggt tgccgacatc ctgttcacca tcgctgttaa agagctgccc ggcattttcg
    19981 ctatcacgaa atagcggcaa ttcgcgatct tcaaaactgt gtcgacgctg acgggtcagc
    20041 agtttcgcca gataagcagg atctttaata tcgccccagt aataacggca ggggttggta
    20101 aacaggagat ggatttcaat atgtttaccc agcgcctgta gcgcctggag ataaacaggc
    20161 ggtaacgcgg aaataccgca tataaagacg cgcgaaggta gccccggcgg gcaggtcgtc
    20221 gcggactcca gcgtttcgat aaagcgctga tagagattgg cgcggtgcca gcgcggttgc
    20281 ccgagttgat gggtatattc caccaacgcc ttccacaacg gcgcttgcca ggcctgtgct
    20341 tctcccagcc cttcaaccaa atgtcctgtt tcccactgtg ccagccagtc cggacgatag
    20401 accagatact ggtcaaacag gtccgccgct tttgaagaaa gctggaacag ttttcgcttg
    20461 tcgctatcgt cagtcagata atgccgcaac agggtaaagt cttcgcgctc caacaattgc
    20521 ggcagcagag tcatcagttt ccagctcatg ctctgtttgt taaaggcgct ctctttgggg
    20581 atttccggta acacccggac gaacatatcc cagataaagc tcgctggcag cggaaaatca
    20641 atgtttgccg caataccaaa cttttgcgac agggtcattt gcagccactg cgccataccg
    20701 gtactttgca ccagaatcat ctctggttcg aaaggatcgt ccagccgttc gcgttcgaca
    20761 ataaactcca tcaacgcttc cagcacgtcc agacgattgg aatggtagac ccttaacata
    20821 gcggctcctg actactgacg attcgggcaa tgcaggcggg tcatctcgcc ttctctgccc
    20881 ccgggtgaaa ctagcgtaac gctgatgctg acacatcccg cctgcgatgt ctgcattcgg
    20941 ttgacctgcc agttggcagg tggcgaaatc gcgcgcagtt gcgtttgctg ccaaccatgc
    21001 cgccagagct gttggtactg gtttctgctg gcgagactgt tcattaatgt tcgctggata
    21061 cccgataacg cagtgacaat catcaccatc agcaccatcg caaccattac ctccggcagg
    21121 ctaaagcctt gttgattctt cagggaagct gacataacgc cctctctttc agcggacaaa
    21181 aatcgctcca gccgcgtggc gaaaaaacaa tgtttccatc aatgacttcg cctgttcgcc
    21241 acaacgaaac gccttcataa ccggcaatca ataaggcttc attatctgcc agtaaacgca
    21301 aacaaacctg ggcatcggtt ccagcgtact gcgagcactg aactgctggc tgcgtctgcc
    21361 aggagtgcat ttttccccac gccagcgccg actgaacgat ggcctggcgg cgcaatgact
    21421 gactttccat gctcacgcga gaggcaaaac tgcgatcctg ctgactcatt ccttgcaata
    21481 gcaagctacc caaaaccagc agcatcagga ccagagccag tgacgaaaca cctttttcgc
    21541 ggttcacagg ttgaatcctg tcacgctata gctggcatcc accacggttt gcggttcaga
    21601 cttactggca gcacgcatat taaccgtcaa caccggcgag aagccgctga catcctgacg
    21661 tacgacctga aaagtgtcga taatgatggc atccggatta gtgactttat cccagccctt
    21721 accttcacag gatgtcgcac cgcgtagcgt ttccagcaca tgctccttca gacgaaatcc
    21781 aatctggtca gactctttta ccggttcgcg atcccagata ccgttactgt tcgcatccca
    21841 ctgcacaatg atacagtcac cctgtccgac aatttccagc ccttcgccgg tacagctgcc
    21901 atgacaataa cccgccctct ggagatgctt cgcgacggta aatacccgca gccagatttc
    21961 atcttccagc gccagcttac gggtgctcgt taaactttca cgctgtaacg caggcagaaa
    22021 gcgtgcagcc cccagcaaca atacgctact gatcgccata gcaatcaaca cttccagcag
    22081 agaaaaacct tgctctttta caggcatcct tctgtttctc cttgctgaca aagccggagt
    22141 cttccccacg gcgaaaccac cagccaccac tcgcccgttg agtttttgaa gcgaatatgc
    22201 ccggcccatg cggtattgcg caggccaaag aaagcaagcg aaggtgtcag gtcgctcatt
    22261 tcgacttcgg gccagcgtgg cacaaagacc aatggtgaac tgccatgaca ggtattggcc
    22321 ccagcagcgg aactcacaag gcaccataac gtcccctccc tgataacgct gatactgtgg
    22381 tcgcggttat gccagttggc atcttcacgt aaatagagca aatagtcccg cgcctggctg
    22441 gcggtttgcc atagccgttg cgactgctgc cagtattgcc agccatagag tccacttgcg
    22501 cttagcatga ccaaaatcag catcgcgacc agcgtttcaa tcagcgtata accacgttgt
    22561 gttttcatgc cggcagtatg gagcgaggag aaaaaaagac gagggccagt ttctatttct
    22621 tcggcgcatc ttccggacta tttacgccgt tgcaggacgt tgcaaaattt cgggaaggcg
    22681 tctcgaagaa tttaacggag ggtaaaaaaa accgacgcac actggcgtcg gctctggcag
    22741 gatgtttcgt aattagatag ccaccggcgc tttaatgccc ggatgtggat cgtagccttc
    22801 aatctcaaag tcttcgaaac ggtagtcgaa gatggattcg ggtttacgtt tgataatcaa
    22861 cttcggcagc ggacgcggtt cgcggcttaa ttgcagatga gtttgatcca tatgattgct
    22921 gtacaggtgc gtgtcgcctc ccgtccagac aaaatcgccc acttccagat cacactgctg
    22981 cgccatcata tgcaccagta acgcgtagct ggcaatgtta aacggcaggc cgaggaaaac
    23041 gtcacaggag cgctgataaa gctggcaaga gagtttgccg tctgccacat agaactggaa
    23101 gaacgcatgg cacggtgcca gcgccatttt atccagttcg cctacgttcc acgctgaaac
    23161 aataatgcgg cgcgaatccg ggtcgttttt cagctggttc agtaccgtag tgatctggtc
    23221 aatatgacga ccatccggcg ttggccaggc gcgccactgt ttaccataca ctggcccgag
    23281 gtcgccgttt tcatcggccc attcgtccca gatggtgaca ttgttttcgt gtagataagc
    23341 aatgttagtg tcgccctgca gaaaccacag cagttcatgg atgatggaac gcaggtggca
    23401 acgtttagtt gtcaccagcg ggaatccatc ctgcaggtta aaacgcatct gatgaccaaa
    23461 aatggaaagc gttccggttc cggtacggtc gtttttctgt gtgccttcgt cgagcacttt
    23521 ttgcatcagt tctaaatact gtttcatggt tcctcaggaa acgtgttgct gtgggctgcg
    23581 acgatatgcc cagaccatca tgatcacacc cgcgacaatc atcgggatgg aaagaatttg
    23641 ccccatgctg atgtactgca cccaggcacc ggtaaactgc gcgtcgggct ggcggaaaaa
    23701 ctcaacaatg atgcgaaacg cgccgtagcc aatcaggaac aagccagaga cagctcccat
    23761 tgggcgcggt ttacgaatat acaggttgag gataataaac agcaccacac cttccagcag
    23821 cagctcgtaa agctgtgatg ggtggcgcgg cagcacaccg taagtgtcga aaatggattg
    23881 ccactgcggg ttggtttgca gcagcaaaat atcttctgta cgggagcctg ggaacagcat
    23941 ggcaaacggg aagttcgggt caacgcggcc ccacaattca ccgttaataa agttgcccag
    24001 acgcccggca ccaagaccaa acggaatgag tggtgcgata aaatcagaaa cctggaagaa
    24061 ggaacgttta gtacggcggg caaagataat catcaccacg ataacgccaa tcaggccgcc
    24121 gtggaaagac atgccgccgt cccagacacg gaacagatac agcggatcgg ccataaactg
    24181 cgggaaattg tagaacagaa cataaccaat acgtcccccg aggaagacgc cgaggaagcc
    24241 cgcatagagt aagttttcaa cttcattttt ggtccagccg ctgcccggac gattcgcccg
    24301 tcgtgttgcc agccacattg caaaaatgaa acccaccaga tacatcaggc cgtaccagtg
    24361 aagcgccacg ggtcctattg agaaaatgac cggatcaaac tccggaaaat gcagatagct
    24421 actggtcatc tgtcaccaca agttcttgtt atttcgctga aagagaacag cgattgaaat
    24481 gcgcgccgca ggtttcaggc gctccaaagg tgcgaataat agcacaaggg gacctggctg
    24541 gttgccggat accgttaaaa gatatgtata tgatccgcgc tataaccctc cgcgaatcag
    24601 cccgcccatg ccgcgacgct ccataaaggc tgcaacctga tggcgaactt cggtcgccag
    24661 ttgcgcttcc agactacgct gcgcaagatt ttctgcttcg gcataatcaa tgcgccgcag
    24721 caggtatttt acccgcgcta cagaacgtcc gttcatagac agatggcgat acccaagccc
    24781 aatgaggatt gccacgcaca tgggatcgcc cgccatttca ccgcacaaac ggagatcgat
    24841 tccatgtatt tccgcttccc gggcgatcat cgccagagct cgtaacattg caggatgaag
    24901 actgtcataa atgttcgcca cccgggtatt gttgcgatca acggccagaa tgtattgagt
    24961 cagatcgttg gtgccaacag agatgaaatc gacccgcttt gccagatgcg gcagcataaa
    25021 taccattgac ggcacttcca gcatgatgcc gatacgtggt ttgggaattt cgtaaccgat
    25081 catctcctcg acttcacgtc cggcacgttc aatcaggcgg cgtgcttcat caacttcatc
    25141 gaggcttgtg accatcggca acagaatatt caggttgccc gtagcggcat tagcacgcag
    25201 catcgcccgc acctggatca agaagatctc cggctgatcg agcgtaatgc gaatcccacg
    25261 ccaacccagg catggattct cttcgctgat cggcatgtaa ggcagctgct tatctgctcc
    25321 gacatccagc gtacgcaagg tgacgggttt atcattgaac atttgcagca tcccctgata
    25381 ctgcgccacc tgttcttctt ccgacgggaa accactttgc agcatgaatg ggatttcagt
    25441 gcgataaaga ccgatgccat caatacggct gcccagtttt tcttcatgtt ccgggcttaa
    25501 accagcattg agcatgactt ttatacgctc accgcttttt aactgcgcgg gtaaattgac
    25561 gtcatcttcc gccagacggc taagctcaat ctcttcacta attagccgct gatattcttg
    25621 cagcagtacc ggctccggat cgaccagcaa ttcaccgcga tagccatcaa cgatcagcgt
    25681 cctacgatgc agcaccgaag gctgaatatc cgcgcccatc acggtaggga tccccagcgc
    25741 acgtaccatg atcgcagcat gggagttggc tgcgccatct cgcacgacaa caccgactaa
    25801 gcgatcctgg ggcagctcag caagagttgt cgctgacagt tcatccgcca ccagaatgaa
    25861 acgttccggc caggcgttcg gcccttgatt agcgtcatca agatgaaaca gcaatcgctg
    25921 acccagcgca cgtaaatcgc cagcccgctc tttgagatag ttatcgctta gcgcggcaaa
    25981 ctgttcggca aatttttcaa tgaccgtttt taccgcccac tctgccaccg agcctttatc
    26041 aacctcggca aacaattcgc gacgcagccg ggtgtccgaa agcaggtgcg agtaaagatc
    26101 gaaaatagcc gccgtttctt tttgtgcacc ggcggcaaag cgtttgctgt agcggcgaaa
    26161 ctcgtttgcc gcttcttcca gcgccccggt cagtcgttcg cgttccagag ccggatccag
    26221 cgttgatgcc tgatacacct gttccattaa aggtaacgtg gcatcctgcc agccttcggc
    26281 aatcgccaca ccaggtgctg ccggtaatgc gcggattcgc gtctggcgat attgcccaaa
    26341 cagggcagtc aactgcgact gagaaagaat agctgccatc tgggtggcaa gcgtcaccag
    26401 gaaggattct tcactttcgt catactggcg caactctcgt tgctgtacca ccagtacacc
    26461 aagcaactgg cgacgttgaa taattggtac gcctaaaaac gcgcggaaac gttcttcttt
    26521 tacggagggg atgtatttga agctggggtg cttttgcgca tctgcaaggt ttatcggttc
    26581 cgccagcctg ccaaccaggc cgacgatccc ttcatcaaac gcgagcgtta cagtgcgacc
    26641 gcgtggtttt ttcagccccc gggtcgccat caggtagtaa caacgtcgat catgatcggc
    26701 caggtagacc gaacagacct cggtatccat cgcaagacag atgtcggtaa ccagaatatt
    26761 taacgcctca ttcaggcgtg gtgcgctggc taccttttcg actatttcgc gcaggcgagt
    26821 gagcataatt ggcgtgactt aacctctttt acgtcgataa gcagatgcgt tttgtggttt
    26881 tggcgtattt tcctgcagtg acatcaccac actcgcgaac tctttcatta ccctacggta
    26941 gacatcacgt ttaaatgaca ccacctgtct gaccggatac cagtaactta cccatcgcca
    27001 gccgtcaaac tctggtgtac tgctggtttg catattgatt tctgcatcgc cgctcaccag
    27061 ctgcaagaga aaccattttt gtttttggcc gatacaaacc ggcttcgtgt cccaacgcac
    27121 caaacgtttc ggtaatttgt agcgcaacca gttacgcgtt gaagcaagga ttcgaacgtc
    27181 tttgcggctt aatcctactt cttcaaacaa ttcacggtac atcgcctgct ctgcggattc
    27241 tccggggttg attccgcctt gcggaaattg ccaggagtgc tgaccaaatc gccgggccca
    27301 cattacctgc ccctggcgat tacaaatcac gatacctacg tttgggcggt agccatcgtc
    27361 atcaatcacc ggactacctc aaaataaagc tttatatacg aatgattgtt tcatactcca
    27421 ggaagacggt aaaccactct ctgcagggca ttacacacta ataacaattg aataactcac
    27481 agttatgtgc agagttataa acagaggaag gggtggatag ccgtttttat tcaccttttc
    27541 tgtggataga gttgtgaaga actacggaat tactacggga aaacccggag cattctgaat
    27601 aagcccgata tagacatttt aaaatattca ttattagtca atgcattaca tgtaatttga
    27661 gtaataaaaa agagtaattc gtgacccagg tcacacctct catttacggg ttggcgaaag
    27721 atcaaccaat gccgtattta tccacagaat gtgccactaa gttaagcact gaaccactaa
    27781 aaactggagt ttcatcgcac gtcaaggctg taaatggaaa cagtagtgga ggtttttcac
    27841 agttatccca gctttctgtg gataacatgg tgtaagatcc tgtttatttt cagtgaccag
    27901 atttggaaaa cctattgcag tgttgcgcaa ctcgattacc ggcagcctaa aaagcaatat
    27961 aaatcaggga attgaacaac acatgtggaa aaagttacac tgcgaatatt cggcacataa
    28021 ttgctgtttg ttttttaatc aaggtatcat gacatgtccc aacctcgccc actgctctct
    28081 cctcccgaaa ctgaagaaca gttgttagcg caagcacagc aactttctgg ttatacattg
    28141 ggagaactgg cggcacttgc cgggcttgtt acgccagaga atttaaaacg cgataagggc
    28201 tggattggcg tgttactgga gatctggcta ggtgccagcg cagggagtaa acctgagcaa
    28261 gattttgccg ctctgggcgt ggaacttaaa actatccctg tggatagtct tggtcgtccg
    28321 ctggaaacaa cattcgtttg tgttgccccg ttaacgggta atagcggggt gacctgggaa
    28381 accagccatg tgcgccacaa gctcaaacgc gtactgtgga taccggttga aggcgagcgc
    28441 agcatcccgc tggcgcagcg tcgcgtagga tcaccgttgc tgtggagccc gaatgaagag
    28501 gaagaccgac agctacgcga agactgggaa gaattaatgg atatcattgt tctcggtcag
    28561 gttgagcgga tcaccgctcg tcacggggaa tatttacaga taagaccgaa agcagcgaat
    28621 gcgaaagcgc ttaccgaagc cattggtgcc cggggcgaac ggattctgac gctgccacgc
    28681 ggcttttatt tgaagaagaa tttcaccagt gcactactgg cccgtcattt tctgatccag
    28741 tagccatcgc tttgacctgc cgctttccgg gcatataatt accgcttcat ttttttggca
    28801 gggcttttta gatgttattt gcatggataa ccgatcctaa cgcctggctt gcgctcggta
    28861 cgctgacgct gctggagatc gttcttggga tcgacaatat tattttcctt tctctggtgg
    28921 tggcaaagct tcccacagca caacgtgctc atgcgcgccg tctggggttg gcgggagcca
    28981 tggttatgcg tctggcgctg ctggcatcaa tcgcctgggt tacgcgcctg acaaatccgc
    29041 tttttacaat attcagtcag gaaatttctg cccgtgattt gattctgctt ctgggtggct
    29101 tgttccttat ctggaaagcc agcaaggaaa tccacgaatc cattgaaggt gaagaagaag
    29161 ggctgaaaac acgcgtttca tcattcctcg gcgctatcgt gcagattatg ctgctggata
    29221 ttatctttag cctcgactcg gtgattacgg ctgtgggtct gtcagatcac ctgtttatta
    29281 tgatggcagc cgtggtgatt gccgtaggcg tgatgatgtt cgccgcgcgc tcgattggtg
    29341 attttgtcga acgccatcct tcggtaaaaa tgctggcgct ctctttcctg attctggtgg
    29401 gctttaccct gattctggaa agtttcgaca tccacgtacc gaaaggttac atctacttcg
    29461 cgatgttctt ctctattgcg gttgaaagcc tcaacttgat tcgcaacaaa aagaatccgc
    29521 tctgatactc cgtacgctct cctgcgggag ggcgtactca ctccttttac cctcacagtt
    29581 taagattttc ctgctttcaa gatatataac gtcggtttat aaacagacta ttatcatagg
    29641 taggccaaat gaggataacc ggatgaaaaa atgggcagta ataatttctg cagtcggact
    29701 ggcgtttgct gtttccgggt gttccagtga ttacgtcatg gcgaccaaag atggccgtat
    29761 gattttgacc gatggaaaac ctgaaattga tgatgatacc gggctggtga gttatcacga
    29821 tcagcaaggt aacgcgatgc aaattaaccg tgatgatgtt tcgcaaatta ttgaacgtta
    29881 acaaataagg tcagcatccg gctggcctta agatttttct ctttcccttt tcccttccct
    29941 ctgccatttt tatattcctt atgtcgtgat tataaaaagg aaacggctat gcaatatcac
    30001 cgtatacccc acagttcgct ggaagtcagc acgctggggc ttggcacgat gacgtttggt
    30061 gaacagaaca gcgaagccga cgcccacgca caactcgact atgccgtcgc tcagggcatt
    30121 aaccttatcg acgttgccga aatgtaccca gtacctccgc gccccgaaac gcaagggtta
    30181 accgaaacct acgtcggcaa ctggctggcg aaacatggca gccgcgaaaa gttaattatc
    30241 gcctccaaag tgagcggacc gtcgcgcaat aatgacaagg gcatccgccc ggatcaggcg
    30301 ctggatcgga agaatatccg cgaagcgctg catgacagcc tcaagcgcct acagactgat
    30361 tacctcgatc tttatcaggt gcactggccg cagcgcccga ccaactgctt cggcaaactc
    30421 ggttatagct ggacggattc tgcgcctgcg gtttcgctgc tggatacgct ggacgcactg
    30481 gcagagtacc aacgcgcggg aaaaattcgt tatatcggcg tgtcgaacga aactgcattt
    30541 ggcgtaatgc gctacctgca tctggcggac aaacacgatc tgccgcgtat tgtcaccatt
    30601 cagaaccctt acagtctgtt aaaccgcagt tttgaagtag gtctggcaga agtcagccag
    30661 tatgaagggg tcgaactgct ggcctattcg tgcctgggtt tcggcacgct gaccgggaaa
    30721 tatctcaatg gtgcaaaacc cgctggcgca cgtaatacgc tctttagtcg gttcacccgc
    30781 tatagcggtg agcaaacgca aaaagccgtc gcggcgtatg ttgatatcgc cagacgtcat
    30841 ggcctggacc ctgctcagat ggcgctcgcg tttgtacgcc gtcaaccgtt tgttgccagc
    30901 actctgctgg gcgcaaccac gatggatcag ctgaaaacta acatcgaaag tttgcatctg
    30961 gagttaagcg aagacgtatt agctgaaatt gaagcggtgc atcaggttta tacttatccg
    31021 gcaccataag attaacgccg gttaaaaccg gcgttaaata ttaatgacgg cgctgccaga
    31081 tccacagcgc cgttattgcc agcgcaaaca gcgcaccgaa gccaatgcca atgggcacga
    31141 ccgggatgcc tatcattacc gccagcgagt aaatgcccag catcaacaac atggcgctgt
    31201 tttcgccaag gttttgtact gcaatcgcat tccccgcccc gacgcttttt ttaccccgct
    31261 cctgtagcaa cgcattgagc ggaacgacaa aaaagccccc catcacgcca atcagcatca
    31321 acaaggcata ggctggcagc agctcgtgtt gcagggaaaa aatcagtacc accacgccaa
    31381 tcaaaatccc ggctggcata cagcgtgaca cggtttccag cgtaactaac ttcgctgccg
    31441 cacctgcgcc aaccacgata ccaatcgcta ccatcgcgtt gagataggtg ggcgtagcgt
    31501 tatcggtaat gcccagcgcc accggtaccc acagcaccaa caggaaacgc agcgtgacac
    31561 ccgctcccca gaataaactg gtgcccacca gcgaaaaacg cgtttcacca ttgcgccata
    31621 gcgaggtgca ggcattcagg aaactgcggg tcatgttgat gagattccag gactgccccg
    31681 gacgcgccgc cgccagtttg ggaatgtaga tattggcaac gaccgcacca ccgtaggcca
    31741 gtgcgcatgc ggccagggcg acgaggacat gccagtcagc cagcacacca ccggctacgg
    31801 aaccgagcaa aatcgccgct atggtagaag cttccattaa accgttagct ttcactaact
    31861 tactacccgt ggttaattcg ccgagaatac cgtatttcgc cggtgaatag gctgcagcac
    31921 caacacccac cagcgtatag ccgagaaacg gattgatacc aaagcagata ctggctgcgc
    31981 ccagcagctt caggccgttg gcaaacatca tcacccggcc tttggcgaag ctatccgcca
    32041 cctgcccgac aaacggcgca aaaagaatgt aagcacctac aaacaccatt tgcaggatgg
    32101 gctggctcca ctccggatag aactgcgctt tcagtaacgc cagagtggca aacagtaggg
    32161 cattatcgcc aaacgcagag agaaactgcg ccacgataac cgctttcatc cccttcgacc
    32221 acaacgaagt gttagtgtgc actgactcac tcatcgtgtt gttccgcttc gtctacccag
    32281 cttttcaacg tgacaaagtc aggtttgccg ctgccaagta atggcatctg tttcagatag
    32341 cgaatatcgc gcggtacagc aagctccggc acgccgtgct cgcgggcata ctgttgcaac
    32401 ttatcgcgcg tcagttcgtt atctgtggtg aaaagcacca gtgcctcgcc tttgctggca
    32461 tcgctcttaa tcgcagtggc atggacttta tctggcgaaa caccaagtgc cagttgttcc
    32521 accatttcca gcgacaccat ttcgcctgca attttggcaa agcgttttgc gcggccctga
    32581 atctgcacaa agccctgctc gtcaaaacgc acaatatcgc cagtgtcata ccagccgcgc
    32641 tccatttcgc cgcgaacatt ctcggcggtg ggcacttcca gtacacctgg cttctccacc
    32701 cgcagatagc cgttcattat gttcggccct ttcagttgca ggcgtccgcc ctcttcgata
    32761 ccagggaccg acaacaggcg cgcatccatt cctggtagaa tacgccctac cgtaccgggt
    32821 ttcgccgcca tcggtacgtt gatagaaacg acaggcgcgc attcggtcac gccgtagcct
    32881 tcaaggatgc gcaggccaaa tttatcctgc caaagctgtt tggtactttc ttgtaatttt
    32941 tctgcgcctg ccaccacata gcgtagacga tagaagtcat acgggttggc gaaacgcgcg
    33001 tagtgaccga ggaaagtcga ggtgccgaac aacacggtgc aactgcggtc atacaccaac
    33061 tccggcacaa tgcggtaatg cagcgggctt ggataaagga acacttctgc acctgtaagc
    33121 agtggcgtaa acaggcctac cgtcagccca aaggagtgaa acagcggtaa cgccgacata
    33181 aagcgatcgt tggtggtgaa gtcggcaatc gttttaatct gctcgacatt cgccagaatg
    33241 cttttatggc tatggacgac gcctttcgga tggccttcag aaccggaggt aaagaggatc
    33301 agcgcctctt cttccggctg ctgtttaacc tgtgccagac gcggcatcag caaatgagcg
    33361 aagatccata ctttgtcggc agtggtgaca tctgctttta aatcttccag atagacccag
    33421 cgcacctgag taagttgctc cggcagatgc cagagtttgc ctttatcgag aaactggcgg
    33481 gaagtgaaga tggttttgat ttcagccgcc gtaatagcac tggtcagccc ttttaccccg
    33541 gcagtgtagt tcatcattgc gggcatgcgg cgacgggcga tggccccaaa aatcactgcc
    33601 gcactgatgc ctgcattggg cagcattaag ccgatgcgtt cgccttcaac actgtatttt
    33661 tcaaggatgc gtccaacaaa cagcgttttc gtaagcaatt tgcgatagga gtctggggta
    33721 aagttgacgt cttcgacaca tttcttcccg gctccgaagc ggtacattgc actcagtaaa
    33781 gattcgtaca gcgtttcacg cgggcgcacc gccattcgcg cttccatcat tatttgatgc
    33841 agcatttcgc cagcgatttt gcgacggtca cgggcacgcg gcgcatccgg catcgccacc
    33901 tgcgttggtg gcaaaatatg cagagtaatt tgcgggaaca agcgacgttt aaccagacct
    33961 ttcaggcggc tgaagtgcgt aagttccgcc ccttcaatac gcacaggaat aaccgttgca
    34021 ccagacttcg ccgcgacaaa acccgcgcca tcgtagattt tcatcagcga gcctgtagtg
    34081 gtgatgcgtc cttcagggaa aatcaccact ggtcggccct gttccaccag acgtaccaga
    34141 tgtttaatag ccataggttg cgtcgggtcg agaggaacaa agtcgataaa tgatttcagc
    34201 caacgcatat accactgttg gcttattgag gtgtaaacgg caaacactgg acgcacaggt
    34261 aaaaacagtc caagcaaaat gccatcaata aaagagacgt gattaggcgt aattagaacg
    34321 cgctcgccct tcagtgcctg ggtgtcaccc gtaacgcgaa cgcgatacaa aacacggcac
    34381 aaatttcgaa aaaagctaaa aagcattcca actccctttg ctctgattca gtaaaagcga
    34441 atggagggag attacacgag ataaagaacg cgagcgacag taaattaggt gcgaaaaaaa
    34501 acctgcgcat ccgcgcaggt tggtgcaaga gacagggtac gaagagcgta ccgaataatc
    34561 tcaccaatca atacctctgg gatcttgatt gtggtctgca cgacgactct tcgccagcga
    34621 gaaaacgcaa aggaatgaag ggaaatgcaa cgaggtgtgt aaattgtcgg ttactgttac
    34681 agattgatga ccggcaaaaa aaaacctgcg catctgcgca ggctggtgta attcatgtgc
    34741 tcaacccgaa gttgacttca cctatcaata cctctgggat caccacttta gcaacctgaa
    34801 gccaaacgcc accagcggtc aatcgcaaca gcgtttcgca aagtgtaacc aaaggtttgc
    34861 aatctctttt tttgtcttac ttatttgcgt ttggctcaca ttcccacgat gaaaacacgc
    34921 caccccttga accaacgggc gttttccgta acactgaaag aatgtaagcg tttacccact
    34981 aaggtatttt catggcgacc ataaaggatg tagcccgact ggcaggcgtt tcagtcgcca
    35041 ccgtttcccg cgtcattaat aattcaccta aagccagtga agcttcccgg ctggctgtgc
    35101 atagtgcaat ggagtctctt agctatcacc cgaacgccaa cgcccgtgcg ctggcgcagc
    35161 agaccactga aacggtcggt ctgatcgttg gtgatgtttc cgatccgttt ttcggtgcaa
    35221 tggtgaaagc ggtcgaacag gtggcttatc acaccggtaa tttcttattg attggcaacg
    35281 gttaccacaa cgaacaaaaa gagcgtcagg ctattgagca actgatccgc catcgctgtg
    35341 ctgcgttggt cgtccatgcc aaaatgatcc cggatgccga tttagcctca ttaatgaaac
    35401 aaatgcccgg tatggtgctg atcaaccgta tcctgcctgg ctttgaaaac cgttgtattg
    35461 ctcttgacga tcgttacggt gcctggctgg caacgcgtca tttaattcag caaggtcata
    35521 cccgcattgg ttatctgtgc tctaaccact ctatttctga cgccgaagat cgtctgcaag
    35581 ggtattacga tgcccttgct gaaagtggta ttgcggccaa tgaccggctg gtgacatttg
    35641 gcgaaccaga cgaaagcggc ggcgaacagg caatgaccga gcttttggga cgaggaagaa
    35701 atttcactgc ggtagcctgt tataacgatt caatggcggc gggtgcgatg ggcgttctca
    35761 atgataatgg tattgatgta ccgggtgaga tttcgttaat tggctttgat gatgtgctgg
    35821 tgtcacgcta tgtgcgtccg cgcctgacca ccgtgcgtta cccaatcgtg acgatggcga
    35881 cccaggctgc cgaactggct ttggcgctgg cggataatcg ccctctcccg gaaatcacta
    35941 atgtctttag tccgacgctg gtacgtcgtc attcagtgtc aactccgtcg ctggaggcaa
    36001 gtcatcatgc aaccagcgac taaccgcagt taaagcaatt ccagcgccag taattcttcg
    36061 atggtctggc gacggcgaat caaccgcgcc tgaccattat caaacagaac ttctggtaac
    36121 agcggacggc tattgtagtt ggatgacatt gatgcgccat atgcccctgt atcatgcagt
    36181 accagataat cacccgcctt cacttccggc aaggcgcggg tttcaacatt tcccccttcc
    36241 tgctgggtaa agacatcgcc cgattcacat aatggcccgg cgacgacggt ttccaccgtt
    36301 ggcgcgtgtt ccagagaacg accatcagct gccagggcac tgatatggtg gtaactaccg
    36361 tacattgccg ggcgcatcag atcgttgaac ccagcatcaa ccagcacaaa gtggcggcta
    36421 cccatttgtt tgacgctccg cacctgagta attaatacgc cagactgcgc taccaggaag
    36481 cgacccggtt caatttccag tttcacaggg tggcccaaat ggcgggcgat ttgctcacgc
    36541 gcggcattcc acagaccata ataatgttcg gtatcaaccg cctcttcacc ctgttgataa
    36601 ggaacagaaa gcccaccgcc cgcagagata gcctgtaaat cctgaccgaa ttcgatgacc
    36661 tgacgcacca tagcaccaca cacctgttcc agatgggcat aatcaacgcc agaaccaatg
    36721 tgcatgtgaa tgccgaccag ctgcagatga tgacgttgta tcacgtccag tgcggcgggc
    36781 agatcggtgt accagatacc gtgcttgctg ttttcgccac cggtattggt tttttggcta
    36841 tgtccgtgac caaaccccgg attaacgcgc agccataccc gatgccctgg cgaaaccagg
    36901 cccagttggt cgagcatatc aacagaaccc gcattcaccg gaatttgcaa ttcactgacg
    36961 cgttcaagcg tcgcctgatc gataacatct gccgtaaaaa caatatcatc ggggtgcgtt
    37021 tgcggattgt aacccgccgc caacgcacgc tctatttcgc ctaacgagac ggaatccact
    37081 ttcacgccct gctcacgcat taagcgcaaa atatgaatat tggaacaggc tttctgtgca
    37141 aagcgcacca catcaaactg tttcagcgct gcaatctgcc gacgaataat ttgcgcatcg
    37201 tagacccaca ccgggcagcc aaattcagcg ggcaaacgca gcagattttc ggcggtgaga
    37261 tcggtatcgg tgctgaacag tgaatgtggc ataacaaact ccagataagt gcttttttat
    37321 gattacgcca catcataaaa agaataaaaa atatcgattt atgtcgagtc tatgcaaaaa
    37381 tgatatggat taccggattg cgagagagcg ctaatggccg ccgttaactt acgtcatatt
    37441 gaaatttttc atgcggtaat gaccgccgga agcctgactg aggcagcaca cctgctacac
    37501 acctcacagc caaccgtcag ccgcgaactg gcgcgctttg agaaggtgat cgggctaaaa
    37561 ttgtttgagc gcgtacgtgg acgattacat cctaccgtgc aaggactgcg tctgtttgaa
    37621 gaagtgcaac gatcctggta cggactggat cgcattgtca gcgccgcaga aagtctgcgc
    37681 gagtttcgcc agggagaact gtctattgcc tgcctgccgg tcttttcgca atctttttta
    37741 ccgcagctcc tgcaaccctt tctggcacgt tatcccgatg tcagcttaaa tatcgtgccc
    37801 caggaatcac cgctacttga agagtggctc tcggcccagc gtcatgattt aggactcact
    37861 gagacactcc atacgcctgc gggaacagaa cgtaccgaat tactctcttt agatgaagtg
    37921 tgtgtgttac ctccgggtca tccgctggcg gtaaaaaagg tattaacgcc ggatgatttt
    37981 cagggtgaga actacatcag cctttcccgt actgacagct atcgccagtt gctggatcag
    38041 ctatttactg aacatcaggt taaacgacgc atgatcgtag aaacccacag cgccgcgtca
    38101 gtctgcgcaa tggtacgggc gggggtaggt gtttcggtgg ttaacccgct caccgcactg
    38161 gattatgcgg caagcggttt agtggtgcgg cggttcagta ttgcggttcc gttcaccgtc
    38221 agcctgatcc gccccctgca ccgcccgtca tcagcgctgg tgcaggcgtt tagtgagcat
    38281 ttacaagcgg ggttaccgaa actggtcact tctcttgacg ctattttgtc gtcagctacg
    38341 acagcataaa agcgacagca tcctcggcat ggatcgccgc agtatcaaac acaggcaaaa
    38401 cactgcgctc ttctggcacc agtaaaccaa tttctgtgca gccaaaaatg acgccctgtg
    38461 cgccctgttc tgcaaggcga gcaatcactt gcgcataata agcgcgtgac gcttcggtaa
    38521 attgccccag acacagttct tcaaaaataa tctgattaat tttcgcccgt tcatccgctt
    38581 caggaataag acaattgatg gaaaattgtt ccgtcagccg cccgcgataa aaatcctgtt
    38641 ccatggtgta acgcgtaccc agcagcgcca cacgagtcat tccggccccg gtaattgcac
    38701 gtccggtggc atccgcaatg tgtaagaaag gcagagtgca acgtgactca atggcatccg
    38761 ccactttatg catcgtattg gtacataaca caataccttc tgcgcccgcc cgctgtaagc
    38821 caagcgccgc ctcagccaga atgtccccgg ttttatccca ttccccgcga cgctggcact
    38881 catctatttc atgaaaatcg acgctatgta gcagcacttg cgcagagtga agcccaccaa
    38941 gccgctgttt aatgccttca tttatcagac gatagtaagg aatggtggat tcccagctca
    39001 ttcctcccag caaaccaatt gttttcattc ctctctcctg atgtgtgtta ccgcaacaag
    39061 gctgaataag gaacgagaca aacgcctcaa cggccaggtg cccgatctct attaacgaaa
    39121 aaagggccgg atgtacagca catccggccc gtgaaatcag acgccgatat ttctcaactt
    39181 ctcgcctgcc atcagtttgc gttcgatatg ttccagcgtg acatttttgg tttccggaat
    39241 gagccagaaa gtgatgccca caaacgcaat gttcagcgca gtgtagagcc agaacgtacc
    39301 ggcagcgcca atgctatcaa gcagtgtcag gaaggtcgcg ccgataatca tattcgacac
    39361 ccagtttgtc gtcgtcgaac aggtaatacc gaaatcgcgg catttcagcg gctgaatttc
    39421 agagcacagg atccacacca ctggcgcggc gctcatcgca taaccggcaa tacacatcat
    39481 cgtcatgcca acagagagcc aggacaagcc actggaagcc gtaccgttat caaactgcat
    39541 caggcaatag cccagcacca gagtgcctaa cgccatcacg ctgaaaccaa ttttcagagc
    39601 cggtttacga cctgctttat ctaccgtaaa gaccgcaatg aaggtcgcga acataaaggt
    39661 cagtcccacg accagagtcg caatcatctg ttgttctgtg gtcgtaaagc ccgccatttt
    39721 gaagatacgc ggcgcatagt acatgatgat gttcataccg gtaaactgct gcatcgcctg
    39781 caacaacata ccgagaaaca cagcacgacg gacgttacgg ttgatcttaa acagtgccca
    39841 accgccttgt tttaacttca ggctttcacg aatttcgttg agttcttctc gcgctttttc
    39901 cgacgtatcg cgcagcatac gcaacacttc ttccgcctca atatgacgcc ccttttccgc
    39961 cagccagcgc gggctatttg gcaggaagac caccagaata atcagcagga ctgctggtaa
    40021 agcaagaacc cccaacattg cgcgccagtt accgctataa ctgaacgctg tatcggataa
    40081 aaacgccagc acgatgccga gtgtgaccat caactggtac atactgatca tcttaccgcg
    40141 aacgttttca cttgccattt cagaaagata cagaggagcg gtgtaagacg cgatcccgac
    40201 agcaatgccc agcaccacac gagcggcgat taacatctct acgctggtcg caaaagcgga
    40261 ccctatagaa ccgagtacaa acaggatggc ccccgccatc aggctgtatt tacgacccag
    40321 gcggaacgac agccaaccat taaacagcgc accaattgct gcgccgagca tcatgctact
    40381 aaccacccat tcctgcaaac gactggtcag cacaaagtga tcggtaatga acggcaacgc
    40441 tccggcgatt acgccgatat caagaccaaa taacaatcct gcgaccgcag cagctaccga
    40501 aacaaacata ttcatacgcc gcgtatcccg caaagaacgt ggcgttaaag cagattccgt
    40561 attgatagta accatttttt cctgccagca gagagtaaga catagtgaaa aaatacgtga
    40621 acaactcacg caggtgtcag gtcggaaaca gcataaatat ggattaaatt gctgcgacat
    40681 gtcgttatgt gatggatatt ccaattttca aattaagttg aattattgag attattatta
    40741 accacctaat tttacagcag ataaaattca taaagttcat taattgataa ttaatatgga
    40801 ttatttcata accatgatat ggattatgat gatctacagg tataaaaaac cctgccatgc
    40861 ggcagggtca taaaagtaag aagaatgaat taacgcgcca gccaaccgcc atccacggca
    40921 atggtataac cattcacata atctgaagcg ctggaggcaa ggaacactat cggccccatc
    40981 aggtcactcg gcagtcccca acgaccagct ggaatgcggt cgagaatttc cgcgctacgt
    41041 tgttcatctg cccgtagttg ttgagtattg ttggtcgcca tgtaacccgg agctatcgca
    41101 ttaacattaa tgttgtgttt agcccattcg ttcgccatca atcgcgtcac acccatcacg
    41161 ccgctttttg atgcggtata agaaggcaca cggatcccgc cctggaagga gagcattgac
    41221 gcgatattga taatcttgcc gccattgcct tgcgcgataa agtgtttcgc cgctgcctga
    41281 gacatgaaga atacgctctt gatattcagg ttcatgacat cgtcccagtc tttttcgctg
    41341 aactcgagag cgtcttcgcg gcgaatcaat ccggcgttat tcaccaggat atcaatatga
    41401 ccaaattcag ctaccgcgcg atccagcagt ccaggaatgc catcaatctt tcgcagatcg
    41461 gcggtcaggc ttaaaaaacg acgccccagc gccgtgacct gctcgatggt ttcagtcggt
    41521 tcaacgatgt taatgccaac aatgtcacag cccgcttgcg ccagccccaa cgccatcccc
    41581 tggcccagcc cagtatcaca accagtgacg accgcaactt taccttcgag agaaaatgca
    41641 cttaaaatca taacaatacc ttattcgttt atgcccacaa ctagcgcaaa tctttaacgg
    41701 ccacatggtc catatcatca aagacctggt tttcaccgac catgccccag ataaaggtat
    41761 aagctttggt tccgacgccg gaatgaatcg accagctcgg ggagatcacc gcctgctcgt
    41821 tatgcatcac aatgtgacgc gtttcttgcg gctgccccat catgtggaaa acgcaggcgt
    41881 catcatccat attgaaatag aaataaactt ccatccggcg ctcgtgagtg tgacacggca
    41941 tggtgttcca caagttacct ggagccagct ccgtcagccc catactcaat tggcaggttt
    42001 ccagcacatc cgggacaaaa tatttgttaa ttgtgcgacg gttactggtg aggttatcgc
    42061 ctaacgtgac tggagatact tcgtccggtg tgactttttt ggtgggatac gtcgtatgcg
    42121 cgggtgcgca attgtaataa aactttgccg gagtggcggt atcaatactg gcaaagacaa
    42181 cttcttttgc acctttaccc acatacaggg cgtcgcggtg accgatttca tagcattggc
    42241 catcgacagt aatcgtaccg gcaccgccaa tattgataac acctaactcg cgacgttcaa
    42301 ggaaatagct tacgccgagt tgtttaccaa cttccccgcc aacggaaacc gttttagtta
    42361 tcggcataat gccgccaaca ataattcggt caatgtggct gtaaaccatg gtgtactcat
    42421 cggcgacaaa tacctcttca accaaaaatt cattgcgcag cccttgggta tccagcgttt
    42481 ttgcgtgcgc actgtggatg ctctgtctta cgtccacatc aacctccgat aatcagtgaa
    42541 gcgtgaaaat agaaaacgat agtgaaacac tgtttcgttt tctctataaa gggatgatat
    42601 gcccatgggc tagggttttc aattaaaaat aaaacaatgt ttcattttta agttaaggat
    42661 taaaaaaagt gcagtgtcga tcacgaatat gtcatgagaa tggaaaaatg agggagccca
    42721 gaaaatgtat gtcgacttgc cagccatcat tattcaacag attaatgacg gcagatattt
    42781 atcggtaagg aggaaatgca gagctactcg tcacgttcaa tggtcaatgc cacgccctgg
    42841 cccccgccga tacaaagcgt tgccagccct ttgcgggcat tacgtttcac catttcatga
    42901 accagagaaa ccaggattcg gcaaccggaa gcgcctatcg ggtgaccgag tgcgatcgcg
    42961 ccaccattga cattgacccg acgctcatcc cactcaagca tcttgccaac cgaaagcgcc
    43021 tgtgcagcaa acgcttcatt agcctcgata agatcgacat cagccaactg ccagcctaca
    43081 cgctccaggc aacggcgggt cgcatacacc ggcgcaattc ccatcaatgc cggatctaca
    43141 ccaacgctgg caaatgcgcg gatgcgggcc agcacgggta aattcaacgc tcgtgctttg
    43201 gcttcgctca tcatcattac cgcagctgcg ccatcgttta tggatgatgc attccccgcg
    43261 gtcacagaac cgagactatc aaatgaagga tttaaacggg ctaaaccttc tgcactggcg
    43321 tcagtgcgtg gctgttcatc ggtatcaaca accaacgtct gaccgttact ttggatcatt
    43381 accgggacga tctcatcttt aaatcgtccg gcgtcaatcg ccgctcgcgc tttttgttgc
    43441 gagctaagtg cgtaagcatc ctgcaactga cggctgatgc catattcgcg agccagattt
    43501 tcggcggtga caccaatatg ataatcattg aaggcatccc acaacccatc atgcaccaga
    43561 ctgtcaacca actggctatt gccaagctgt gcaccggtgc ggctatcagt cagaacatgt
    43621 ggtgcgcggc tcatgttttc ctggccaccg gcgatgacaa tatcagcctc gccacactgt
    43681 atcgcctgag tagccagatg cagtgcttta agcccagaac cgcaaacgtc attaatagtg
    43741 attgcagaaa cgctattagg aagaccacct ttaatagccg attgccttgc cggattctgc
    43801 cctgcccctg cagtcaacac ctgaccaaga attacttcat ccaccgcata tgcaggaacg
    43861 ccggtacgtt ctattaacgc tttcacgacc agactaccaa gttccacggc ggaatgaccc
    43921 gctaacgcac cgcgaaagca gccgataggt gtccgtaacg ccccgacaat cacaacgtct
    43981 ttcatcacaa cctcgcacca attaacagtg caatagtaaa tgattgttaa ttacagttat
    44041 cttaattgtt taaaaaaagt gatttttatc acaaaggaaa tatgcctgag cagtagtcag
    44101 agtcataact ggcacgtaag gtttgcaacc actaacccac caatagaggg gtagataggg
    44161 cgttaatctc ccatacttaa cctggtttat ggtaaattgc cctccatttt gtttaatttg
    44221 tagatgatac gttcagataa tgtctaatat ttggtctaaa gaagaaactc tgtggagttt
    44281 cgcgctctac ggcacagccg ttggtgcagg cacgctcttc cttcctattc agttaggttc
    44341 ggcaggggct gtggtcctgt ttattactgc tctggtcgcc tggcctttaa catattggcc
    44401 acataaagcc ttatgccagt tcatcctctc atcgaaaaca tcagcaggtg aagggataac
    44461 gggcgcagta acacactact atggcaagaa gattggtaat ctgattacca cgctgtactt
    44521 catcgccttt tttgtcgtcg tgttgatata tgcagtggca attaccaact cacttacgga
    44581 acagctggca aagcatatgg ttattgatct tcgcatccgt atgttggtga gtctgggtgt
    44641 tgtattaatc ctgaatctca tttttctgat gggacgccat gcaaccattc gggtaatggg
    44701 ttttttggta ttcccattga ttgcctattt cttatttctt tccatttacc ttgtcggtag
    44761 ttggcaacct gatctattaa cgacccaggt agagttcaat cagaataccc ttcaccagat
    44821 atggatatcg attcccgtga tggttttcgc ctttagccat acgcccatta tttctacgtt
    44881 tgccatagac agacgtgaaa aatatggcga acacgctatg gataaatgca aaaaaattat
    44941 gaaagtcgct tatctcatca tctgcataag tgtactgttc tttgtcttta gctgcctgct
    45001 ttctattcca ccttcgtata ttgaagcggc taaagaagaa ggggtcacca ttttatcagc
    45061 gctttctatg ctgccgaacg ccccagcatg gctgtcaatt tccgggatta ttgtcgcagt
    45121 agttgcgatg tcgaaatcat tcctgggtac gtactttggc gttattgaag gtgccacgga
    45181 ggtcgtcaaa acaacactac agcaggttgg tgtaaagaaa agtcgtgcat ttaaccgcgc
    45241 actatcaatt atgttggtat cgctgatcac cttcattgtt tgttgcatta acccgaacgc
    45301 gatttcgatg atttacgcga tcagcggccc gctcattgcc atgatacttt tcatcatgcc
    45361 tacgttgtca acgtatctga tcccggcgct taaaccctgg cgttccatcg gaaatctgat
    45421 tacgctgatc gtgggtatcc tgtgcgtatc ggtaatgttc tttagctgat atccattgtg
    45481 aatggttcaa aattgctaca attttgaacc attccagttt tcataatgtt cattcgttat
    45541 tattccgcac tatcacttcc ctcatcatat cctagtatta tcagttagtt aaacacacaa
    45601 agagatctga acatcttaaa taagactatt taagatgcat aacttagatt cgcaagatat
    45661 cttccggtca ttcaaaaaca atttgcgata tagatattct cataccatga gatagttatc
    45721 tgaaccaccc tcaaccaggt aagattaaat cagtgaaaca taatcatatt taataacgag
    45781 aaatgcattt taaaatgtct taatcagaat tatagcaaat acagattaat cgcaattttt
    45841 cccagcaaaa ttacaaaatc atggtgtatt gacatcatca atcaccaatg aaattatgca
    45901 attatatacg gatagggagg ttcttaacat ggggctttgt agtcgttata aaagtcttac
    45961 atgcaatagt tgctcaatgc attgccaaat aatgccagaa gagtcaccgc gtttgcagta
    46021 ctgcgcaaac tcgtgttttt gtatgtggcc cgaagaaagt tcatatttta atcgtggtgt
    46081 ggtagaaggt atcttaacaa aaaaccacaa tgcgagatta agcggatata tttttgtcga
    46141 tttttcagta agttttttac gtctattcct tgaaaaagac tggattgact atcttgcaag
    46201 tactgacatg gggattgttt tagtcagcga ccgcaatatg caatcgttag ctaattactg
    46261 gcgaaaacac aactcagcaa tatctgctgt catatataat gatgatggtc ttgatgttgc
    46321 caatgaaaag atcagacaac tatttattgg tcgttattta tcatttacca gaggtaacac
    46381 attaactcag atggaattca ccataatggg gtatatggtt tctggttata atccatatca
    46441 gattgctgaa gttctggata tggatatccg tagcatctac gcgtacaagc aacgaatcga
    46501 aaagagaatg ggtggtaaaa taaacgaatt atttattcgt tcacattcgg tccaacattg
    46561 atactcaacg accagccaga atcatactct gtttatacgg gcatttattg aaatgtccgt
    46621 attttataaa taggccgtcc cctcaagagt aaacaccata gtatttaaaa ccatcacacg
    46681 aaaaattcag aagcattacg aaatatgaat ttacaaacaa tagtggcata aatgttaac
//
LOCUS       DAZUDJ010000035        46438 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.035, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000035 DAZUDJ010000000
VERSION     DAZUDJ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46438
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.035"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            134..1423
                     /gene="hpaG"
                     /locus_tag="ACHY1N_002636"
     CDS             134..1423
                     /gene="hpaG"
                     /locus_tag="ACHY1N_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008704 -
                     5-carboxymethyl-2-hydroxymuconate delta-isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0018800 -
                     5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:1901023 - 4-hydroxyphenylacetate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate degradation bifunctional
                     isomerase/decarboxylase"
                     /protein_id="HFS4044930.1"
                     /translation="MKGTIFAVALNHRSQLDAWQEAFQQSPYKAPPKTAVWFIKPRNT
                     VIGCGEPIPFPQGEKVLSGATVALIVGKTATKVREEDAAEYIAGYALANDVSLPEESF
                     YRPAIKAKCRDGFCPIGETVALSNVDNLTIYTEINGRPADHWNTADLQRNAAQLLSAL
                     SEFATLNPGDAILLGTPQARVEIQPGDRVRVLAEGFPPLENPVVDEREVTTRKSFPTQ
                     PHPHGTLFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQTSVRPNNIEYMHYE
                     AELVVVIGKQARSVSEADAMDYVAGYTVCNDYAIRDYLENYYRPNLRVKSRDGLTPML
                     STIVPKEAIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIA
                     TGTPKGLSDVVPGDEVVVEVEGVGRLVNRIVSEETAK"
     gene            1420..2886
                     /gene="hpaE"
                     /locus_tag="ACHY1N_002637"
     CDS             1420..2886
                     /gene="hpaE"
                     /locus_tag="ACHY1N_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018480 -
                     5-carboxymethyl-2-hydroxymuconic-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:1901023 - 4-hydroxyphenylacetate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-carboxymethyl-2-hydroxymuconate semialdehyde
                     dehydrogenase"
                     /protein_id="HFS4044931.1"
                     /translation="MKKVNHWINGKNVAGNDYFQTTNPATGEVLADVASGGEAEINQA
                     VVAAKEAFPKWANLPMKERARLMRRLGDLIDQNVPEIAAMETADTGLPIHQTKNVLIP
                     RASHNFEFFAEVCQQMNGKTYPVDDKMLNYTLVQPVGVCALVSPWNVPFMTATWKVAP
                     CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVR
                     AVSFTGGTATGRNIMKNAGLKKYSMELGGKSPVLIFEDADIERALDAALFTIFSINGE
                     RCTAGSRIFIQQSIYPEFVKRFAERANRLRVGDPNDPNTQVGALISQQHWEKVSGYIR
                     LGIEEGATLLAGGPDKPSDLPAHLKGGNFLRPTVLADVDNRMRVAQEEIFGPVACLLP
                     FKDEAEGLRLANDVEYGLASYIWTQDVSKVLRLARGIEAGMVFVNTQNVRDLRQPFGG
                     VKASGTGREGGEYSFEVFAEMKNVCISMGDHPIPKWGV"
     gene            2888..3739
                     /gene="hpaD"
                     /locus_tag="ACHY1N_002638"
     CDS             2888..3739
                     /gene="hpaD"
                     /locus_tag="ACHY1N_002638"
                     /EC_number="1.13.11.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008198 - ferrous iron binding [Evidence
                     IEA];
                     GO_function: GO:0008687 - 3,4-dihydroxyphenylacetate
                     2,3-dioxygenase activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxyphenylacetate 2,3-dioxygenase"
                     /protein_id="HFS4044932.1"
                     /translation="MGKLALAAKITHVPSMYLSELPGKNHGCRQGAIDGHKEISKRCR
                     EMGVDTIIVFDTHWLVNSAYHINCADHFEGVYTSNELPHFIRDMTYNYEGNPELGQLI
                     ADEALKLGVRAKAHNIPSLKLEYGTLVPMRYMNEDKHFKVVSISAFCTVHDFADSRKL
                     GEAILKAIEQYDGTVAVLASGSLSHRFIDDQRAEEGMNSYTREFDRQMDERVVKLWRE
                     GQFKEFCNMLPEYADYCYGEGNMHDTVMLLGMLGWDKYDGKVEFITELFPSSGTGQVN
                     AVFPLPA"
     gene            3749..4129
                     /locus_tag="ACHY1N_002639"
     CDS             3749..4129
                     /locus_tag="ACHY1N_002639"
                     /EC_number="5.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-carboxymethyl-2-hydroxymuconate
                     Delta-isomerase"
                     /protein_id="HFS4044933.1"
                     /translation="MPHFIVECSDNIREEADLPGLFAKVNPTLAATGIFPLAGIRSRV
                     HWVDTWQMADGQRDYAFVHMTLKIGAGRSLESRQQAGEMLFELIKTHFAALMESRLLA
                     LSFEIEELHPTLNFKQNNVHALFK"
     gene            4240..5043
                     /gene="hpaH"
                     /locus_tag="ACHY1N_002640"
     CDS             4240..5043
                     /gene="hpaH"
                     /locus_tag="ACHY1N_002640"
                     /EC_number="4.2.1.163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710089.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018817 - 2-oxo-hept-3-ene-1,7-dioate
                     hydratase activity [Evidence IEA];
                     GO_process: GO:0009056 - catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-hept-4-ene-1,7-dioate hydratase"
                     /protein_id="HFS4044934.1"
                     /translation="MFDKHTHTLIAQRLDQAEKQREQIRAISLDYPEITIEDAYAVQR
                     EWVRLKIAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGSDIPTDRFIV
                     PRIEVELAFVLAKPLRGPNCTLFDVYNATDYVIPALELIDARCHNIDPETQRPRKVFD
                     TISDNAANAGVILGGRPIKPDELDLRWISALMYRNGVIEETGVAAGVLNHPANGVAWL
                     ANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGSISCRFV"
     gene            5054..5842
                     /gene="hpaI"
                     /locus_tag="ACHY1N_002641"
     CDS             5054..5842
                     /gene="hpaI"
                     /locus_tag="ACHY1N_002641"
                     /EC_number="4.1.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018802 -
                     2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity
                     [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxoheptanedioate aldolase"
                     /protein_id="HFS4044935.1"
                     /translation="MENSFKAALKAGRPQIGLWLGLSSSYSAELLAGAGFDWLLIDGE
                     HAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGTQTLLVPMVQNADEAR
                     EAVRATRYPPAGIRGVGSALARASRWNRIPDYLQKANDQMCVLVQIETREAMKNLPQI
                     LDVEGVDGVFIGPADLSADMGYAGNPQHPEVQAAIEQAIVQIREAGKAPGILIANEQL
                     AKRYLELGALFVAVGVDTTLLARAAEALAARFGAQATTVKPGVY"
     gene            5966..7342
                     /gene="hpaX"
                     /locus_tag="ACHY1N_002642"
     CDS             5966..7342
                     /gene="hpaX"
                     /locus_tag="ACHY1N_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1901241 - 4-hydroxyphenylacetate
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:1900754 - 4-hydroxyphenylacetate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate permease"
                     /protein_id="HFS4044936.1"
                     /translation="MSDTSPAIPESIDPANQHKALTAGQQAVIKKLFRRLIVFLFVLF
                     IFSFLDRINIGFAGLTMGRDLGLSATMFGLATTLFYAAYVIFGIPSNIMLSIVGARRW
                     IATIMVLWGIASTATMFATGPTSLYVLRILVGITEAGFLPGILLYLTFWFPAYFRARA
                     NALFMVAMPVTTALGSIVSGYILSLDGVMALKGWQWLFLLEGFPSVLLGVMVWFWLDD
                     SPDKAKWLTKEDKKCLQEMMDNDRLTLVQPEGAISHHAMQQRSMWREIFTPVVMMYTL
                     AYFCLTNTLSAISIWTPQILQSFNQGSSNITIGLLAAVPQICTILGMVYWSRHSDRRQ
                     ERRHHTALPYLFAAAGWLLASATDHNMIQMLGIIMASTGSFSAMAIFWTTPDQSISLR
                     ARAIGIAVINATGNIGSALSPFMIGWLKDLTGSFNSGLWFVAALLVIGAGIIWAIPMQ
                     SSRPRATP"
     gene            7352..8242
                     /gene="hpaA"
                     /locus_tag="ACHY1N_002643"
     CDS             7352..8242
                     /gene="hpaA"
                     /locus_tag="ACHY1N_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate catabolism regulatory
                     protein HpaA"
                     /protein_id="HFS4044937.1"
                     /translation="MCDRQIANIDISKEYDESLGTDDVHYQSFARMAAFFGRHMLPHR
                     HEQYFQMHFLNSGQIELQLDDHRYSVEAPLFVLTPPSVPHAFITESDADGHVLTVRED
                     LIWPLLEVLYPGTRETFGLPGICLSLADKPDELAALEHYWQLIERESVEQLPGREHTL
                     TLLAQAVFTLLLRNAKLDDHAASGMRGELKLFQRFNMLIESHFHQHWTVPDYANELHI
                     TESRLTDICRRFANRPPKRLIFDRQLREAKRLLLFSDNAVNNIAWQLGFKDPAYFARF
                     FNRLVGCSPSAYRAKKVPVT"
     gene            8493..10055
                     /gene="hpaB"
                     /locus_tag="ACHY1N_002644"
     CDS             8493..10055
                     /gene="hpaB"
                     /locus_tag="ACHY1N_002644"
                     /EC_number="1.14.14.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016712 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, reduced flavin or flavoprotein as one
                     donor, and incorporation of one atom of oxygen [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase,
                     oxygenase component"
                     /protein_id="HFS4044938.1"
                     /translation="MKPEDFRASTQRPFTGEEYLKSLQDGREIYIYGERVKDVTTHPA
                     FRNAAASVAQLYDALHKPEMQDSLCWNTDTGSGGYTHKFFRVAKSADDLRQQRDAIAE
                     WSRLSYGWMGRTPDYKAAFGCALGANPGFYGQFEQNARNWYTRIQETGLYFNHAIVNP
                     PIDRHLPTDKVKDVYIKLEKETDAGIIVSGAKVVATNSALTHYNMIGFGSAQVMGENP
                     DFALMFVAPMDANGVKLISRASYEMVAGATGSPYDYPLSSRFDENDAILVMDNVLIPW
                     ENVLIYRDFDRCRRWTMEGGFARMYPLQACVRLAVKLDFITALLKKSLECTGTLEFRG
                     VQADLGEVVAWRNTFWALSDSMCSEATPWVNGAYLPDHAALQTYRVLAPMAYAKIKNI
                     IERNVTSGLIYLPSSARDLNNPQIDQYLAKYVRGSNGMDHVQRIKILKLMWDAIGSEF
                     GGRHELYEINYSGSQDEIRLQCLRQAQSSGNMDKMMAMVDRCLSEYDQNGWTVPHLHN
                     NDDINMLDKLLK"
     gene            10073..10585
                     /locus_tag="ACHY1N_002645"
     CDS             10073..10585
                     /locus_tag="ACHY1N_002645"
                     /EC_number="1.14.14.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase reductase
                     subunit"
                     /protein_id="HFS4044939.1"
                     /translation="MQLDEQRLRFRDAMASLSAAVNIITTEGDAGQCGITATAVCSVT
                     DTPPSLMVCINANSAMNPVFQGNGKLCVNVLNHEQELMARHFAGMTGMAMEERFSLSC
                     WQKGPLAQPVLKGSLASLEGEIRDVQAIGTHLVYLVEIKNIILSAEGHGLIYFKRRFH
                     PVMLEMEAAI"
     gene            10978..13128
                     /gene="btsT"
                     /locus_tag="ACHY1N_002646"
     CDS             10978..13128
                     /gene="btsT"
                     /locus_tag="ACHY1N_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313340.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HFS4044940.1"
                     /translation="MDTKKLFKHIPWVILGIIGAFCLAVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGPV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFIRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVVLNPELKMPAMTQYIDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLANETDARFIGYGAMLMESFVAIMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPIIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFIPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLGTVVLIKMKRTQYIWVTVVPAVWLLICTTWALGLKLFSTNP
                     QMEGFFYMASQYKEKIANGTDLTAQQIANMNHIVVNNYTNAGLSILFLIVVYSIIFYG
                     FKTWLAVRNSDKRTDKETPYVPIPEGGVKISSHH"
     gene            13178..13381
                     /gene="yjiX"
                     /locus_tag="ACHY1N_002647"
     CDS             13178..13381
                     /gene="yjiX"
                     /locus_tag="ACHY1N_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HFS4044941.1"
                     /translation="MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSY
                     EEFFRERQNARYGGDGKGGMRCC"
     gene            13392..14348
                     /gene="yjiA"
                     /locus_tag="ACHY1N_002648"
     CDS             13392..14348
                     /gene="yjiA"
                     /locus_tag="ACHY1N_002648"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313338.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HFS4044942.1"
                     /translation="MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDLLDNLDKGNIQFDRLVIECTGMA
                     DPGPIIQTFFSHEILCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKT
                     DVAGEAEKLRERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVVSTKPRFHFIA
                     DKQNDISSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDETPHSTMVFIGIQLPEDEIRAAFAGLKK"
     gene            complement(14426..16966)
                     /locus_tag="ACHY1N_002649"
     CDS             complement(14426..16966)
                     /locus_tag="ACHY1N_002649"
                     /EC_number="3.5.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001569102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008953 - penicillin amidase activity
                     [Evidence IEA];
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin G acylase"
                     /protein_id="HFS4044943.1"
                     /translation="MKNRNRMIVNCVTASLMYYWSLPALAEQSSSEIKIVRDEYGMPH
                     IYANDTWHLFYGYGYVVAQDRLFQMEMARRSTQGTVAEVLGKDFVKFDKDIRRNYWPD
                     AIRAQIAALSPEDMSILQGYADGMNAWIDKVNTNPETLLPKQFNTFGFTPKRWEPFDV
                     AMIFVGTMANRFSDSTSEIDNLALLTALKDKYGVSQGMAVFNQLKWLVNPSAPTTIAV
                     QESNYPLKFNQQNSQTAALLPRYDLPAPMLDRPAKGADGALLALTAGKNRETIAAQFA
                     QGGANGLAGYPTTSNMWVIGKSKAQDAKAIMVNGPQFGWYAPAYTYGIGLHGAGYDVT
                     GNTPFAYPGLVFGHNGVISWGSTAGFGDDVDIFAERLSAEKPGYYLHNGKWVKMLSRE
                     ETITVKNGQAETFTVWRTVHGNILQTDQTTQTAYAKSRAWDGKEVASLLAWTHQMKAK
                     NWQEWTQQAAKQALTINWYYADVNGNIGYVHTGAYPDRQSGHDPRLPVPGTGKWDWKG
                     LLPFEMNPKVYNPQSGYIANWNNSPQKDYPASDLFAFLWGGADRVTEIDRLLEQKPRL
                     TADQAWDVIRQTSRQDLNLRLFLPTLQAATSGLTQSDPRRQLVETLTRWDGINLLNDD
                     GKTWQQPGSAILNVWLTSMLKRTVVAAVPMPFDKWYSASGYETTQDGPTGSLNISVGA
                     KILYEAVQGDKSPIPQAVDLFAGKPQQEVVLAALEDTWETLSKRYGNNVSNWKTPAMA
                     LTFRANNFFGVPQAAAEETRHQAEYQNRGTENDMIVFSPTTSDRPVLAWDVVAPGQSG
                     FIAPDGTVDKHYEDQLKMYENFGRKSLWLTKQDVEAHKESQEVLHVQR"
     gene            complement(17318..17482)
                     /gene="yjiS"
                     /locus_tag="ACHY1N_002650"
     CDS             complement(17318..17482)
                     /gene="yjiS"
                     /locus_tag="ACHY1N_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008786105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1127 domain-containing protein"
                     /protein_id="HFS4044944.1"
                     /translation="MEFHENKAKTPFIRLVQLWHAVRRWRRQMQTRRVLQQMSDERLR
                     DIGLRREDVE"
     gene            17659..19071
                     /gene="yjiR"
                     /locus_tag="ACHY1N_002651"
     CDS             17659..19071
                     /gene="yjiR"
                     /locus_tag="ACHY1N_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFS4044945.1"
                     /translation="MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQ
                     QAYQTLETMRLITPQPRSGYFVAQRKAQPPVPPMTRPVQRPVEITQWDQVLDMLEAHS
                     DNSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLML
                     DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIE
                     IPTDPETGISVEALELALEQWPIKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIV
                     IFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLRVGWVAPGRYHDKLM
                     HMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQTYQRNLALYTCWIREYFPCEIC
                     ITRPKGGFLLWIELPEQVDMVCVARQLCRMNIQVAAGSIFSASGKYRNCLRINCALPL
                     SETYREALKQIGEAVYRAME"
     gene            complement(19313..20257)
                     /locus_tag="ACHY1N_002652"
     CDS             complement(19313..20257)
                     /locus_tag="ACHY1N_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001678496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HFS4044946.1"
                     /translation="MTNFSTSTPHDALFKSFLTHPGTARDFMEIHLPKDLRELCDLDS
                     LKLESASFVDEKLRALHSDILWSVKTREGDGYIYVVIEHQSREDIHMAFRLMRYSMAV
                     MQRHIEHDKRRPLPLVIPMLFYHGSRSPYPWSLCWLDEFAAPTTARKLYSAAFPLVDV
                     TVVPDDEIVQHRRVALLELIQKHIRQRDLMGLIDQLVVLLVTECANDSQITALLNYIL
                     LTGDEARFKAFISELTRRMPQHRERIMTIAERIYNDGWLLGMEKGKEEGEQRLLRLLL
                     QNGADPEWIQKITGLSTEQMQALEQPLPEIKRDPWIEY"
     gene            20724..21956
                     /gene="mdtM"
                     /locus_tag="ACHY1N_002653"
     CDS             20724..21956
                     /gene="mdtM"
                     /locus_tag="ACHY1N_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HFS4044947.1"
                     /translation="MPRFFARHAATLFFPMALILYDFAAYLSTDLIQPGIINVVGDFN
                     ADVSLAPAAVSLYLAGGMALQWLLGPLSDRIGRRPVLITGALIFTLACAATMFTTSMT
                     QFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAAL
                     MHFVHWKVLFAIIAVMGFISFVGLLLAMPETVKRGAVPFSAKSVFRDFRNVFCNRLFL
                     FGAATISLSYIPMMSWVAVSPVILIDAGGLTTSQFAWTQVPVFGAVIVANAIVARFVK
                     DPTESRFIWRAVPIQLVGLALLIIGNLLSPHVWLWSVLGTSLYAFGIGLIFPTLFRFT
                     LFSNNLPKGTVSASLNMVILMVMSVSVEIGRWLWFNGGRLPFHLLAVVAGVIVVFTLA
                     GLLNRVRQHQAAELAEER"
     gene            21997..23277
                     /gene="yjiN"
                     /locus_tag="ACHY1N_002654"
     CDS             21997..23277
                     /gene="yjiN"
                     /locus_tag="ACHY1N_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HFS4044948.1"
                     /translation="MNKLIELRRAKMLALSLLLIAAATFVVTLFLPPNFWVSGVKAIA
                     EAAMVGALADWFAVVALFRRVPIPIISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     VALIRRHEPALLIGNWFSQPENARRVGQHLLQIMSGFLELTDDARIQRLLKRAVHRAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISRDRAHQIRHAFDRATFALIDKLKNDP
                     EMAARADAVKSYLKEDEAFNRYLSELWGDLREWLKADINSEDSRVKERIARAGQWFGE
                     TLIADDALRASLNGHLEQAAHRVAPEFSAFLTRHISDTVKSWDARDMSRQIELNIGKD
                     LQFIRVNGTLVGGCIGLILYLLSQLPALFPLGNF"
     gene            23393..24544
                     /gene="yjiM"
                     /locus_tag="ACHY1N_002655"
     CDS             23393..24544
                     /gene="yjiM"
                     /locus_tag="ACHY1N_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418755.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="double-cubane-cluster-containing anaerobic
                     reductase"
                     /protein_id="HFS4044949.1"
                     /translation="MSLITDLPAIFDQFSEARQKGFLTVMDLKERGIPLVGTYCTFMP
                     QEIPMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLV
                     VGETTCDGKKKMYEYMAEFKPVHVMQLPNSVKDDASRALWKAEMLRLQKTVEERFGHE
                     ISEDALRDAIALKNRERRALANFYHLGQLNPPALSGSDILKVVYGATFRFDKEALINE
                     LDAMTARVRQQWEEGQRLALRPRILITGCPIGGAAEKVVRAIEENGGWVVGYENCTGA
                     KATEQCVAETGDVYDALADKYLAIGCSCVSPNDQRLQMLSQMVEEYQVDGVVDVILQA
                     CHTYAVESLAIKRHVRQQHNIPYIAIETDYSTSDVGQLSTRVAAFIEML"
     gene            24554..25321
                     /gene="yjiL"
                     /locus_tag="ACHY1N_002656"
     CDS             24554..25321
                     /gene="yjiL"
                     /locus_tag="ACHY1N_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313324.1"
                     /note="YjiL, as found in Escherichia coli, is a homolog of
                     the activator ATPases of enzymes such as lactoyl-CoA
                     dehydratase, (R)-phenyllactate dehydratase, and
                     2-hydroxyisocaproyl-CoA dehydratase. The typical substrate
                     of those enzymes is acyl-CoA with an OH at the
                     beta-position. YjiL is the putative activator for the
                     cognate protein YjiM, a putative 2-hydroxyacyl-CoA
                     dehydratase with unknown specificity, encoded by the
                     adjacent gene; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-hydroxyacyl-CoA dehydratase activator
                     YjiL"
                     /protein_id="HFS4044950.1"
                     /translation="MTYSIGIDSGSTATKGILLADGVITRRFLVPTPFRPATAITEAW
                     ETLREGLETTPFLTLTGYGRQLVDFADKQVTEISCHGLGARFLAPATRAVIDIGGQDS
                     KVIQLDDDGNLCDFLMNDKCAAGTGRFLEVISRTLGTSVEQLDSITENVTPHAITSMC
                     TVFAESEVISLRSAGVAPEAILAGVINAMARRSANFIARLSCEAPILFTGGVSHCQTF
                     ARMLESHLGMPVNTHPDAQFAGAIGAAVIGQRVRTRR"
     gene            25318..25575
                     /gene="ytiA"
                     /locus_tag="ACHY1N_002657"
     CDS             25318..25575
                     /gene="ytiA"
                     /locus_tag="ACHY1N_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HFS4044951.1"
                     /translation="MKEFLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRDLRGGCGLC
                     IWLTCPPGEEIQWVIPGQTESIYCQQDGVWRCIAHYGVSPR"
     gene            25640..26500
                     /gene="yjiK"
                     /locus_tag="ACHY1N_002658"
     CDS             25640..26500
                     /gene="yjiK"
                     /locus_tag="ACHY1N_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418753.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdiA-regulated domain-containing protein"
                     /protein_id="HFS4044952.1"
                     /translation="MTKSISLSKRISVIVILFAIVAVCTFFVQSCARKSNHAASFQNY
                     HATIDGKEIAGITNNISSLTWSAQSNTLFSTINKPAAIVEMTTNGDFIRTIPLDFVKD
                     LETIEYIGDNQFVISDERDYAIYVISLTPNSEVKILKKIKIPLQDSPTNCGFEGLAYS
                     RQDHTFWFFKEKNPIEVYKVNGLLSSNELHISKDEALQRQFTLDDVSGAEFNQQKNTL
                     LVLSHESRALQEVTLVGEVIGEISLTKGSRGLSHNIKQAEGIAMDASGNIYIVSEPNR
                     FYRFTPKSSH"
     gene            26568..27746
                     /gene="yjiJ"
                     /locus_tag="ACHY1N_002659"
     CDS             26568..27746
                     /gene="yjiJ"
                     /locus_tag="ACHY1N_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4044953.1"
                     /translation="MPSSSHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAE
                     GAFSFSQLSWIASGNYAGYLAGSLLFSFGAFHQPSRLRPLLLVSALASGLLILAMAWL
                     PPFILVLLIRFLAGVASAGMLIFGSTLIMQHTRHPFVLAALFSGVGIGIALGNEYVLA
                     GLHFAFSSQTLWQGAGALSGMMLIALTLLMPSKKHAIAPMPLAKTEQQIMSWWLLAIL
                     YGLAGFGYIIVATYLPLMAKDAGSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPC
                     LTANLLVQAISVLLTLASDSPLLLIISSIGFGGTFMGTTSLVMTIARQLSVPGNLNLL
                     GFVTLIYGIGQILGPALTSMLGNGTSALAGATLCGAAALFIAALISTVQLFKLQVVTS
                     "
     gene            complement(27759..28313)
                     /gene="kptA"
                     /locus_tag="ACHY1N_002660"
     CDS             complement(27759..28313)
                     /gene="kptA"
                     /locus_tag="ACHY1N_002660"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HFS4044954.1"
                     /translation="MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLIL
                     CAQKAGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQF
                     LYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKR
                     GIPFWQAENGVWLTSTVAVEFLEW"
     gene            28563..29246
                     /gene="yjiH"
                     /locus_tag="ACHY1N_002661"
     CDS             28563..29246
                     /gene="yjiH"
                     /locus_tag="ACHY1N_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HFS4044955.1"
                     /translation="MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWR
                     VFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGFLFALELAPSVILSLGIISITDG
                     LGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEMTERDKV
                     IFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVILVFKFVGANILRVWLNFEER
                     RNPTQGAQA"
     gene            29243..29704
                     /gene="yjiG"
                     /locus_tag="ACHY1N_002662"
     CDS             29243..29704
                     /gene="yjiG"
                     /locus_tag="ACHY1N_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HFS4044956.1"
                     /translation="MTTQVRKNVMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMGGAVGVAASLATAGALTGHDVTV
                     LLPAMYLIGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV"
     gene            29717..30889
                     /gene="iadA"
                     /locus_tag="ACHY1N_002663"
     CDS             29717..30889
                     /gene="iadA"
                     /locus_tag="ACHY1N_002663"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFS4044957.1"
                     /translation="MIDYTAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNIPS
                     DIVPDCTVVDLSGQILCPGFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVG
                     LLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIG
                     VKCAISDHRSAAPDVYHLANMAAESRVGGLLGGKPGVTVFHMGDSKKALQPIYDLLEN
                     CDVPISKLLPTHVNRNVPLFEQALEFARKGGTIDITSSIDEPVAPAEGIARAVQAGIP
                     LARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKDYDFSISDALRPLTS
                     SVAGFLNLTGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA"
     gene            30954..31865
                     /gene="hypT"
                     /locus_tag="ACHY1N_002664"
                     /gene_synonym="qseD"
     CDS             30954..31865
                     /gene="hypT"
                     /locus_tag="ACHY1N_002664"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HFS4044958.1"
                     /translation="MDDCGAILHNIETKWLYDFLTLEKCRNFSQAAVSRNVSQPAFSR
                     RIRALEQAIGVELFNRQVTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRK
                     IKIAAAHSLSLGLLPSIISQMPPLFTWAIEAIDVDEAVDKLREGQSDCIFSFHDEDLL
                     EAPFDHIRLFESQLFPVCASDEHGEALFNLAQPHFPLLNYSRNSYMGRLINRTLTRHS
                     ELSFSTFFVSSMSELLKQVALDGCGIAWLPEYAIQQEIRSGKLVVLNRDELVIPIQAY
                     AYRMNTRMNPVAERFWRELRELEIVLS"
     gene            complement(31858..32250)
                     /gene="iraD"
                     /locus_tag="ACHY1N_002665"
     CDS             complement(31858..32250)
                     /gene="iraD"
                     /locus_tag="ACHY1N_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313312.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HFS4044959.1"
                     /translation="MMRQSLQAVLPEISGNKTSLLRKSVCSDLLTLFNSPHSALPSLL
                     VSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIM
                     LYHDDEPLTFDLVWDNGGWRSATLENVS"
     gene            complement(32247..32330)
                     /gene="idlP"
                     /locus_tag="ACHY1N_002666"
     CDS             complement(32247..32330)
                     /gene="idlP"
                     /locus_tag="ACHY1N_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iraD leader peptide IdlP"
                     /protein_id="HFS4044960.1"
                     /translation="MENEHQYSGARCSGQAAYVAKRQECAK"
     gene            complement(32446..32589)
                     /gene="ytiD"
                     /locus_tag="ACHY1N_002667"
     CDS             complement(32446..32589)
                     /gene="ytiD"
                     /locus_tag="ACHY1N_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YtiD"
                     /protein_id="HFS4044961.1"
                     /translation="MADYAEINNFPPELSSGGDKYFHLHNYSEYSEYTSGFFLSLMIF
                     IKS"
     gene            32922..33752
                     /gene="yjiC"
                     /locus_tag="ACHY1N_002668"
     CDS             32922..33752
                     /gene="yjiC"
                     /locus_tag="ACHY1N_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313311.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2686 family protein"
                     /protein_id="HFS4044962.1"
                     /translation="MSMPLSNALQSQIITDNHFLHHPKVDSELTRKYERARLDKENIY
                     LLPLARGNNHNYDGKSVVEIRKLDISKEPWPFNYVTETCRESDGITTTGRMLYRNLKI
                     TSALDEIYGGICKKAHAATELAEGLRLSLFMKSPSYPVEDYTVHEITLGPGCNVPGYA
                     GTTIGYISTLPVSQAKRWTNEQPRIDIYIDQIMTVSGVANSSGFALAALLNANIELGN
                     DPIIGIEAYPGTAEIHAKMGYKVIPGDENAPLKRMTLQPSSLPELFELKNGEWNYIGK
                     "
     gene            complement(33893..34666)
                     /gene="uxuR"
                     /locus_tag="ACHY1N_002669"
     CDS             complement(33893..34666)
                     /gene="uxuR"
                     /locus_tag="ACHY1N_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HFS4044963.1"
                     /translation="MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLD
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDNSGSQNTDSPDANVCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFDSWPLDKVDA"
     gene            complement(34881..36341)
                     /gene="uxuB"
                     /locus_tag="ACHY1N_002670"
     CDS             complement(34881..36341)
                     /gene="uxuB"
                     /locus_tag="ACHY1N_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HFS4044964.1"
                     /translation="MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHH
                     LLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALH
                     PEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS
                     AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENV
                     TFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKV
                     GAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTNPDYRKAAFSLMMQE
                     QAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQN
                     GGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKVNAQYQGADRVKALLGLS
                     GIFADDLPQNADFVGAVTAAYQQLCERGARECVAAL"
     gene            complement(36422..37606)
                     /gene="uxuA"
                     /locus_tag="ACHY1N_002671"
     CDS             complement(36422..37606)
                     /gene="uxuA"
                     /locus_tag="ACHY1N_002671"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709912.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFS4044965.1"
                     /translation="MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEE
                     ILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAV
                     RFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKA
                     IIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEE
                     HRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SR"
     gene            37946..39289
                     /gene="gntP"
                     /locus_tag="ACHY1N_002672"
     CDS             37946..39289
                     /gene="gntP"
                     /locus_tag="ACHY1N_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease GntP"
                     /protein_id="HFS4044966.1"
                     /translation="MHVLNILWVIFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGM
                     DLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQL
                     SVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQ
                     PGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVD
                     MNNLPSFGVSILVPLIPAIIMISTTITNIWLVKDTPAWEVVNFIGSSPIAMFIAMVVA
                     FVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSH
                     GNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLAT
                     AAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA"
     gene            complement(39532..40434)
                     /gene="fimH"
                     /locus_tag="ACHY1N_002673"
     CDS             complement(39532..40434)
                     /gene="fimH"
                     /locus_tag="ACHY1N_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria D-mannose specific adhesin FimH"
                     /protein_id="HFS4044967.1"
                     /translation="MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVN
                     LAPAVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSS
                     YPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNS
                     DDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYL
                     SGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTAN
                     YARTGGQVTAGNVQSIIGVTFVYQ"
     gene            complement(40454..40957)
                     /gene="fimG"
                     /locus_tag="ACHY1N_002674"
     CDS             complement(40454..40957)
                     /gene="fimG"
                     /locus_tag="ACHY1N_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimG"
                     /protein_id="HFS4044968.1"
                     /translation="MKWRKRGYLLAAILALASATIQAADVTITVNGKVVAKPCTVSTT
                     NATVDLGDLYSFSLMSAGAASAWHDVALELTNCPVGTSRVTASFSGAADSTGYYKNQG
                     TAQNIQLELQDDSGNTLNTGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQAVI
                     SITYTYS"
     gene            complement(40970..41500)
                     /gene="fimF"
                     /locus_tag="ACHY1N_002675"
     CDS             complement(40970..41500)
                     /gene="fimF"
                     /locus_tag="ACHY1N_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimF"
                     /protein_id="HFS4044969.1"
                     /translation="MRNKPFYLLCAFLWLAVSHALAADSTITIRGYVRDNGCSVAAES
                     TNFTVDLMENAAKQFNNIGATTPVVPFRILLSPCGNAVSAVKVGFTGVADSHNANLLA
                     LENTVSAASGLGIQLLNEQQNQIPLNAPSSAISWTTLTPGKPNTLNFYARLMATQVPV
                     TAGHINATATFTLEYQ"
     gene            complement(41510..44146)
                     /gene="fimD"
                     /locus_tag="ACHY1N_002676"
     CDS             complement(41510..44146)
                     /gene="fimD"
                     /locus_tag="ACHY1N_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher FimD"
                     /protein_id="HFS4044970.1"
                     /translation="MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSS
                     AELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSE
                     QGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTTMIQDATAHLDVGQQRLNLTI
                     PQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIG
                     AWRLRDNTTWSYNSSDRSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGI
                     NFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTIND
                     IYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEK
                     PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD
                     DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGV
                     IQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGL
                     NTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMS
                     HDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANI
                     GYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTD
                     WRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKL
                     LMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV
                     ANYQLPPESQQQLLTQLSAECR"
     gene            complement(44213..44938)
                     /gene="fimC"
                     /locus_tag="ACHY1N_002677"
     CDS             complement(44213..44938)
                     /gene="fimC"
                     /locus_tag="ACHY1N_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418736.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HFS4044971.1"
                     /translation="MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEAGVALGATR
                     VIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVKDGRFIVTPPLFAMKGKKENTLR
                     ILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPP
                     DQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGTRVLENALVPPMGESTVKLPSDAG
                     SNITYRTINDYGALTPKMTGVME"
     gene            complement(44975..45514)
                     /gene="fimI"
                     /locus_tag="ACHY1N_002678"
     CDS             complement(44975..45514)
                     /gene="fimI"
                     /locus_tag="ACHY1N_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418735.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4044972.1"
                     /translation="MKRKRLFLLASLLPMFALAGNKWNTTLPGGNMQFQGVIIAETCR
                     IEAGDKQMTVNMGQISSNRFHAAGEDSAPVPFVIHLRECSTVVSERVGVAFHGVADGK
                     NPDVLSVGEGPGIATNIGVALFDDEGNLVPINRPPANWKRLYSGSTSLHFIAKYRATG
                     RRVTGGIANAQAWFSLAYQ"
     gene            complement(45579..46127)
                     /gene="fimA"
                     /locus_tag="ACHY1N_002679"
     CDS             complement(45579..46127)
                     /gene="fimA"
                     /locus_tag="ACHY1N_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HFS4044973.1"
                     /translation="MKIKTLAIVVLSALSLSSAAALADTTTVNGGTVHFKGEVVNAAC
                     AVDAGSVDQTVQLGQVRTASLKQAGATSSAVGFNIQLNDCDTTVATKAAVAFLGTAID
                     ATRTDVLALQSSAAGSATNVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARY
                     YAIGEATPGAANADATFKVQYQ"
BASE COUNT        10898 a        12135 c        11864 g        11541 t
ORIGIN      
        1 attatcttta aatgtaaata gtttgttaat tagatcacat ttacatcact tacttttgcc
       61 aaactacgca atcgggaata aaagtaatca ttaacatatt aatgattaag atgatcgaat
      121 ccgaggagtg gtaatgaaag gcactatctt cgccgtagca ttgaaccatc gcagccagct
      181 tgatgcatgg caggaagcgt tccagcaatc cccctacaaa gccccgccta aaactgcggt
      241 ctggtttatt aaaccgcgca atacggtgat tggttgcggt gaaccgattc cctttccaca
      301 gggtgaaaag gtactgagcg gtgcgacagt tgcgctgatt gtgggaaaaa cggcgacgaa
      361 agtacgtgaa gaagatgcgg cagagtacat cgccggatat gcgctggcta acgacgtcag
      421 cctgccggaa gagagctttt accgtccggc aatcaaagca aaatgtcgtg atggattctg
      481 ccccattggc gaaaccgtgg ctctcagcaa tgtcgataat ctgaccatct ataccgagat
      541 caacgggcgt cctgccgatc actggaacac cgccgattta caacgtaacg ccgcgcagtt
      601 gctgagcgcc ctgagcgaat ttgccacact gaatccaggc gatgccattc tgctcggcac
      661 gccacaggcg cgcgtggaaa tacagccagg cgatcgcgtt cgtgttctcg cagaaggttt
      721 cccgccgctg gaaaatccgg tagtggacga acgtgaagtg accacgcgca agagcttccc
      781 aacgcagcca cacccgcacg gcacgctgtt tgccctcggc ctgaactacg ccgaccacgc
      841 cagcgaactg gaatttaagc caccggaaga accgctggtg ttcctgaaag cgccaaatac
      901 cctcactggc gataaccaga cctccgtgcg tccaaacaat attgaataca tgcactatga
      961 agcggagctg gtggtagtta ttggcaaaca ggcgcgtagc gtcagcgaag ccgatgccat
     1021 ggattatgtc gcgggctaca ccgtgtgtaa cgactacgcc attcgcgact atctggaaaa
     1081 ctactaccgc cctaacctgc gggtaaaaag ccgcgacgga ctgacgccga tgctttcaac
     1141 catcgtgccg aaagaggcga tcccggaccc gcataatctg acccttcgca ccttcgtcaa
     1201 cggcgagtta cgccagcaag gcaccaccgc cgatctgatc ttcagcgtgc ccttcctgat
     1261 cgcctactta agcgaattta tgaccctgaa tccgggcgac atgatcgcca ccggcacacc
     1321 aaaaggctta tctgacgtgg tgcctggcga tgaagtagtg gtggaagtag aaggcgtggg
     1381 ccgcctggtg aaccgaattg tgagtgagga aacagcgaaa tgaaaaaagt aaatcattgg
     1441 atcaacggca aaaatgttgc aggtaacgac tacttccaga ccaccaatcc ggcaacgggt
     1501 gaagtgctgg cggatgtggc ctctggcggt gaagcggaga tcaatcaggc ggtagtggca
     1561 gcgaaagagg cgttcccgaa atgggccaat ctgccaatga aagagcgtgc gcgcctgatg
     1621 cgccgtctgg gcgatctgat cgaccagaac gtgccagaga tcgccgcgat ggaaaccgcg
     1681 gacaccggcc tgccgatcca tcagaccaaa aatgtgttga tcccacgcgc ttcccacaac
     1741 tttgaatttt tcgcggaagt ctgccagcag atgaacggca agacttatcc ggtcgacgac
     1801 aagatgctca actacacgct ggtgcagccg gtaggcgttt gtgcactggt gtcaccgtgg
     1861 aacgtgccgt ttatgaccgc cacctggaag gtcgcgccgt gtctggcgct gggcaatacc
     1921 gcggtactga aaatgtcgga actctccccg ctgaccgccg accgcctggg tgagctggcg
     1981 ctggaagctg gtattccggc gggcgtgctg aacgtggtac agggctacgg cgcaaccgca
     2041 ggcgatgcgc tggtccgtca tcatgacgtg cgtgccgtgt cgttcaccgg cggtacggcg
     2101 accgggcgca acatcatgaa aaacgccggg ctgaaaaaat actccatgga actgggcggt
     2161 aaatcgccgg tgctgatttt tgaagatgct gatattgaac gcgcgctgga cgccgccctg
     2221 ttcaccatct tctcgatcaa cggcgaacgc tgcaccgccg gttcgcgcat ctttattcag
     2281 caaagcatct acccggaatt cgttaaacgc tttgccgaac gcgccaaccg tctgcgcgtg
     2341 ggcgatccga acgatccgaa tacccaggtt ggcgcgctta tcagccagca gcactgggaa
     2401 aaagtctccg gctatatccg tctcggcatt gaagaaggcg caaccctgct ggcgggcggc
     2461 ccggataaac cgtccgacct gcctgcgcac ctgaaaggcg gcaacttcct gcgcccaacc
     2521 gtgctggcag acgttgataa ccgtatgcga gtcgcccagg aagagatttt cgggccggtc
     2581 gcctgcctgc tgccgtttaa agacgaagcc gaaggcttac gtctggcaaa cgacgtggag
     2641 tacggcctcg cgtcgtacat ctggacacag gatgtcagca aagtgttacg cctggcgcgt
     2701 ggcattgaag ctggcatggt gttcgtcaac acccagaacg tgcgtgacct gcgccagcca
     2761 tttggcggcg taaaagcctc cggcaccggg cgtgaaggcg gtgagtacag cttcgaagtg
     2821 ttcgcggaaa tgaagaacgt ctgcatttcc atgggcgacc atccaattcc gaaatgggga
     2881 gtctgatatg ggtaagttag cgttagccgc caagatcacg cacgtaccgt cgatgtatct
     2941 ctctgaactg ccagggaaaa accacggttg ccgccagggc gcgatcgacg ggcataaaga
     3001 gatcagcaag cgttgccggg aaatgggcgt cgataccatt atcgttttcg atacccactg
     3061 gctggtcaac agtgcttatc acatcaactg tgcagaccat tttgaaggcg tctacaccag
     3121 caacgagctg ccgcatttta tccgcgatat gacctacaac tacgagggca acccggagtt
     3181 ggggcagctt attgccgatg aagccttaaa gctcggcgtg cgggcaaaag cgcacaacat
     3241 tcccagcctg aaactggaat acggcacgct ggtgccaatg cgctacatga atgaagacaa
     3301 gcacttcaaa gtggtttcca tttcagcttt ctgcactgtt cacgattttg ccgacagccg
     3361 caagctgggc gaggcgattc tgaaagcgat cgaacagtac gacggcaccg tggcggtcct
     3421 tgccagcggt tcgttatcgc accgctttat tgacgatcag cgagcggaag aagggatgaa
     3481 cagctacacc cgcgagttcg accgccagat ggacgagcgt gtggtgaagc tgtggcgcga
     3541 aggccagttc aaagagttct gcaatatgct gccggagtac gccgactact gctacggcga
     3601 aggcaatatg cacgacacgg tgatgctgct ggggatgctc ggctgggata aatacgacgg
     3661 caaggtggag tttatcaccg agctattccc aagctctggc accggtcagg ttaacgctgt
     3721 tttcccgctt cccgcgtaag gacgttttat gccgcacttt atcgttgaat gcagtgacaa
     3781 catccgcgaa gaagccgacc tgccggggtt gttcgccaaa gtgaatccga cgctggcagc
     3841 cacgggtatt tttccgctgg cgggtattcg cagccgcgtg cattgggtcg atacctggca
     3901 gatggccgac gggcagcgtg attatgcctt cgtgcatatg acgttgaaaa tcggcgcagg
     3961 tcgcagcctg gaaagccgtc agcaggcggg tgaaatgctg tttgaactga ttaaaacgca
     4021 cttcgccgcc ctgatggaga gccgcctgct ggcgttgtcg tttgagattg aagagctgca
     4081 tccgacgctg aattttaaac aaaacaacgt gcacgcattg tttaagtagc gcgcagattg
     4141 cccggtggcg ctgcgcttac cgggcctaca aaaccccaaa ccgtacaccg taggccggat
     4201 aaggcgcagc cgcatccggc aatgccacag gatatcgcta tgttcgataa acatacccac
     4261 accctgatcg cccagcgtct ggatcaggca gaaaaacagc gcgaacagat ccgcgcgatc
     4321 tcactggatt acccggagat caccatcgaa gacgcttacg cggtgcagcg cgaatgggtt
     4381 cgcctgaaaa tcgccgaagg tcgcacgctg aaaggccaca aaatcggcct gacctcgaaa
     4441 gcgatgcagg caagctcgca gatcagcgaa ccggattacg gcgcgctgct ggatgacatg
     4501 ttcttccacg atggcagcga tatcccgacc gatcgcttta tcgtgccgcg cattgaagtg
     4561 gagctggctt tcgtgctggc aaaaccgctg cgtgggccaa actgcacgct gttcgacgtc
     4621 tacaacgcca cggactacgt gatcccggcg ctggagctga tcgacgctcg ctgccacaac
     4681 atcgatccgg aaacccagcg cccgcgcaaa gtgttcgaca ccatttctga taacgccgcc
     4741 aacgccgggg tgatcctcgg tggtcgtccc attaagcccg atgagttgga tctgcgttgg
     4801 atctccgccc tgatgtatcg caatggcgtg attgaagaaa ccggcgtcgc cgctggtgtg
     4861 ctgaatcatc cggcaaacgg cgtggcctgg ctggcgaaca aactcgcacc gtatgacgta
     4921 caactggaag ccgggcaaat cattctcggc ggttcgttca cccgcccggt tccggcgcgt
     4981 aagggcgaca ccttccacgt cgattacggc aacatgggct ccattagctg ccgctttgtt
     5041 taaggagaga acgatggaaa acagttttaa agcggcgctg aaagcaggcc gcccgcagat
     5101 cggattatgg ctggggctga gtagcagcta cagcgcagag ttactggccg gagcaggatt
     5161 cgactggtta ttgatcgacg gtgagcacgc gccgaataac gtgcaaaccg tgctcaccca
     5221 gctacaggcg attgcgccct accccagcca gccggtggta cgtccgtcgt ggaacgatcc
     5281 ggtgcaaatc aaacaactgc tggacgtcgg cacacaaacc ttgctggtgc cgatggtaca
     5341 aaacgctgac gaagcccgtg aagcggtacg cgccacccgt tatccccccg ccggtattcg
     5401 cggtgtgggc agtgcgctgg cccgagcctc gcgctggaat cgtattcctg attacctgca
     5461 aaaagccaac gatcaaatgt gcgtgctggt gcagatcgaa acgcgtgagg caatgaagaa
     5521 cttaccgcag attctggacg tggaaggggt cgacggcgtg tttatcggcc cggcggatct
     5581 gagcgccgat atgggttatg ccggtaatcc acagcacccg gaagtacagg ccgcgattga
     5641 gcaggcgatc gtgcagatcc gcgaagcggg caaagcgccg gggatcctga tcgccaatga
     5701 gcaactggca aaacgctatc tggaactggg cgcgctgttt gtcgctgtcg gcgttgacac
     5761 caccctgctc gcccgcgccg ctgaagcgct ggcagcacgg tttggcgcac aggccacgac
     5821 cgttaagccc ggcgtgtatt aatgccggat gcgctgcact tatccggcct acactcgcac
     5881 caaaccgtag gccggataag gcgtttacgc cgcatccgcc ataaaccttg tcgtacccta
     5941 caaaaatccc attagaggaa gaaaaatgag cgacacctca cctgccatac cggagagtat
     6001 cgatccggcg aatcagcata aagcgctgac tgccggacaa caggcggtta ttaagaagct
     6061 gtttcgccgc ctgatcgtct ttctgttcgt gctgtttatc ttctcgttcc ttgatcgcat
     6121 caacatcggc tttgccggac tcacgatggg acgcgacctc ggtctgagcg ccaccatgtt
     6181 tggcctcgct accaccctgt tctatgccgc ttatgtcatc ttcggcattc ccagcaacat
     6241 tatgctgagt attgtcggtg cgcggcgctg gatcgccacc atcatggtgc tttggggcat
     6301 cgcctctact gccaccatgt ttgccactgg ccccaccagc ttgtacgtac tgcgtatact
     6361 ggttggcatt accgaagccg gctttctgcc cggcattctg ctgtatttaa ccttctggtt
     6421 tccggcctat ttccgcgccc gtgccaacgc cttgtttatg gtagcaatgc cggtaacgac
     6481 agcgttgggc tcgatcgttt ccggctacat tttgtcgctg gatggcgtca tggcattaaa
     6541 aggctggcag tggctgtttt tgctggaagg cttcccgtcg gtattactcg gcgtcatggt
     6601 gtggttctgg cttgatgact caccggacaa agctaagtgg ctgacgaaag aagacaaaaa
     6661 atgcctgcaa gagatgatgg ataacgatcg tctgacgctg gttcagccag agggagccat
     6721 cagccaccac gccatgcaac aacgcagtat gtggcgggag atcttcactc cggtggtgat
     6781 gatgtatacc ctggcgtatt tctgcctgac caacacactt agtgcgatca gcatctggac
     6841 accgcagatc ctgcaaagtt ttaatcaggg cagcagtaat atcaccatcg gcctgctggc
     6901 cgccgtaccg cagatttgta ccattctcgg gatggtctac tggagccgtc actcagatcg
     6961 ccgccaggaa cgaaggcatc acaccgccct tccttatttg ttcgctgccg caggttggtt
     7021 actggcttcg gcaactgatc acaacatgat ccagatgctg gggatcatta tggcttcgac
     7081 cggatcattc agcgcaatgg cgattttctg gacaacaccg gatcagtcca tcagcctgcg
     7141 ggcacgagcg atcggtattg cggtgatcaa cgccactggc aacattggtt cagcgttaag
     7201 tccgtttatg atcggctggt tgaaagattt gaccggcagc tttaacagtg gattgtggtt
     7261 tgttgccgcg ctgctggtga ttggtgcggg gattatctgg gcgattccaa tgcagtcctc
     7321 ccgtccgcga gcgaccccgt aaggaacgac gatgtgtgac cgtcagattg ccaatattga
     7381 tatcagcaaa gagtacgatg aaagcctggg cacggacgat gtgcattatc agtccttcgc
     7441 ccgcatggcg gccttttttg gccgccatat gctgccacat cgccacgaac agtactttca
     7501 gatgcatttc ctcaatagcg gacagattga gctacaactt gacgatcatc gctactcggt
     7561 ggaagcgccc ctgtttgtcc tgacgccgcc gtcagtacct catgcgttta ttacggagtc
     7621 tgacgccgac ggtcatgtgt tgacggtacg ggaagatctg atctggcccc tgctggaagt
     7681 tctttatccg ggcactaggg aaaccttcgg cctgccgggg atttgcctgt cactggcaga
     7741 taaacccgac gaactggcgg cgctggaaca ctattggcaa ctgatagagc gggaatcggt
     7801 ggaacaactg cctggacggg aacacaccct gacgttactg gcacaggcag tgttcaccct
     7861 actgctgcgt aacgcaaaac tcgacgacca tgccgccagc gggatgcgcg gagaattaaa
     7921 actgttccag cgttttaata tgctgattga aagccatttt catcagcact ggacagtacc
     7981 ggattacgct aacgaactgc atatcaccga atcacgactc acggacatct gccgtcgctt
     8041 tgccaaccgt ccgccaaaac ggttgatttt cgacaggcag ctgcgagaag ccaagcggct
     8101 gctgctgttt tctgataacg ccgtgaacaa tattgcctgg caactcggtt ttaaggatcc
     8161 ggcttatttt gcgcgctttt ttaatcgctt agtcggttgc tcgcccagtg cttatcgcgc
     8221 caaaaaagta cctgtgacgt gaaaatccct tagccttaac gggaaaccag gcaccacctg
     8281 ctattcccct ttctccgcct ggagcaaggg gatttagtaa cgtcaaaaat cgctaaaagc
     8341 gacctcgatc acaaaaccgt acccgacctg aaaagtacca gccattgtcc caaaagtctc
     8401 ttcccgtaat cgcccctgca agcttcaatt gaataacaaa aacaacacac aaaattaaca
     8461 atcgtattcc gattaatact gtagaggtcg acatgaaacc agaagatttc cgcgccagta
     8521 cccaacgtcc gttcaccggg gaagagtatc tgaaaagcct gcaggatggt cgcgagatct
     8581 atatctatgg cgagcgagtg aaagacgtca ctactcatcc ggcatttcgt aatgcggcag
     8641 cgtctgttgc ccaactgtac gacgcgctac acaaaccgga gatgcaggac tctctgtgct
     8701 ggaacaccga caccggcagc ggcggctata cccataaatt cttccgcgtg gcgaaaagtg
     8761 ccgacgacct gcgccagcaa cgcgatgcca tcgctgagtg gtcacgcctg agctatggct
     8821 ggatgggccg taccccagac tacaaagctg ctttcggttg cgcactgggc gcgaatccgg
     8881 gcttttacgg tcagttcgag cagaacgccc gtaactggta cacccgtatt caggaaactg
     8941 gcctctactt taaccacgcg attgttaacc caccgatcga tcgtcatttg ccgaccgata
     9001 aagtgaaaga cgtttacatc aagctggaaa aagagactga cgccgggatt atcgttagcg
     9061 gtgcgaaagt ggttgccacc aactcggcgc tgactcacta caacatgatt ggcttcggct
     9121 cggcacaagt aatgggcgaa aacccggact tcgcactgat gttcgttgcg ccaatggatg
     9181 ccaatggcgt caaattaatc tcccgcgcct cttatgagat ggtcgcgggt gctaccggct
     9241 cgccgtacga ctacccgctc tccagccgct tcgatgagaa cgatgcgatt ctggtgatgg
     9301 ataacgtgct gatcccatgg gaaaacgtac tgatctaccg cgatttcgat cgctgccgtc
     9361 gctggacgat ggaaggcggt tttgcccgta tgtatccgct gcaagcctgt gtgcgcctgg
     9421 cagtgaaact agacttcatt acggcactgc tgaaaaaatc actcgaatgt accggcaccc
     9481 tggagttccg tggtgtgcag gccgatctcg gtgaagtggt ggcgtggcgc aacaccttct
     9541 gggcattgag tgactcgatg tgttctgaag cgacgccgtg ggtcaacggg gcttatttac
     9601 cggatcatgc cgcactgcaa acctatcgcg tactggcacc aatggcctac gcgaagatca
     9661 aaaacattat cgaacgcaac gttaccagtg gcctgatcta tctcccttcc agtgcccgtg
     9721 acctgaacaa tccgcagatc gaccagtatc tggcgaagta tgtgcgcggt tcgaatggta
     9781 tggatcacgt ccagcgcatc aagatcctca aactgatgtg ggacgccatt ggcagcgagt
     9841 ttggtggtcg ccacgaactg tatgaaatca actactccgg tagccaggat gagattcgcc
     9901 tgcagtgtct gcgccaggca caaagctccg gcaatatgga caagatgatg gcgatggttg
     9961 atcgctgcct gtcggaatac gaccagaacg gctggactgt gccgcacctg cacaacaacg
    10021 acgatatcaa catgctggat aagctgctga aataacgcag caggaggtta agatgcaatt
    10081 agatgaacag cgcctgcgct ttcgtgacgc gatggccagc ctgtcggcag cggtaaatat
    10141 tatcaccacc gagggcgacg ccggacaatg cgggattacg gcaacggccg tctgctcggt
    10201 cacggataca ccaccatcgc tgatggtgtg cattaacgcc aacagtgcga tgaacccggt
    10261 ttttcagggc aacggcaagt tgtgcgtcaa cgtcctcaac catgagcagg aactgatggc
    10321 acgccacttc gcgggcatga cgggcatggc gatggaagag cgttttagcc tctcatgctg
    10381 gcaaaaaggt ccgctggcgc agccggtgct aaaaggttcg ctggccagtc ttgaaggtga
    10441 gatccgcgat gtgcaggcaa ttggcacaca tctggtgtat ctggtggaga ttaaaaacat
    10501 catcctcagt gcagaaggtc acggacttat ctactttaaa cgccgtttcc atccggtgat
    10561 gctggaaatg gaagctgcga tttaagctcc agccccttca cgcattcgtc gaaggggcat
    10621 ttttattgtg atctcaatca catatccacc cgatgaataa ttcttgccca accgctcacc
    10681 gccattcctg accgcttaca tccctaaaat aaccactcag ttatttacct tactttacgc
    10741 gcgcgtaact ctggcaacat cactgcagga tagcggtcaa tttacctcct caaacgcaac
    10801 gcaaacctag aacggcttcg gcctatgatt aacaaattac tctatgaatt ttggtttgca
    10861 ggaaggcagc aagtgagtga atccccggga gcttacaaca gtaagtgaca ggggtgaacg
    10921 aacgcaactg ccgcacctgt aagccaaaag acgacgagta aaatgccagg ttttactatg
    10981 gatacgaaaa aactattcaa gcacataccc tgggtgattc tcggaatcat cggtgcattc
    11041 tgcctcgcgg tagttgcatt acgtcggggg gagcacgtca gcgccctgtg gatcgtggtc
    11101 gcctctgtgt cggtgtatct ggtggcgtat cgctactaca gtctgtacat cgcccagaag
    11161 gtgatgaaac tcgaccccac gcgcgcgacg cctgcggtta ttaacaacga cggtctgaac
    11221 tacgttccga ccaaccgtta cgtgttgttt ggtcaccact tcgccgctat cgccggtgct
    11281 ggtccgctgg tcggtccggt tctcgccgca cagatgggct acctgcctgg cacgctgtgg
    11341 ctgctggcgg gggtagtact ggccggtgcg gttcaggact ttatggtgct gtttatctcc
    11401 tctcgccgta acggcgcatc tctcggtgag atgatcaaag aagagatggg accagtaccg
    11461 gggactatcg cgctgtttgg ctgtttctta atcatgatca tcatcctcgc cgtcctggcg
    11521 ctgattgtgg ttaaagccct ggccgaaagt ccgtggggtg tcttcaccgt ttgctcaacc
    11581 gtaccgattg cgctgtttat gggtatctac atgcgcttta tccgtccggg gcgtgtgggt
    11641 gaagtctctg tcattggtat cgtgctgctg gttgcctcta tctacttcgg tggcgtgatt
    11701 gctcacgatc cgtactgggg tccggcactg acctttaaag acaccaccat taccttcgcg
    11761 ctgattggct atgcgtttgt ttccgcactg ctgccggtgt ggctgatcct cgcaccgcgc
    11821 gactatctgg caaccttcct gaaaatcggc gttatcgtcg gcctggcgct gggtatcgtg
    11881 gtgctgaacc cggaactgaa aatgcctgcg atgacccagt acattgacgg tactggcccg
    11941 ctgtggaaag gcgctctgtt cccgttcctg ttcatcacca tcgcctgtgg tgcggtatct
    12001 ggcttccacg cgctgatctc ttccggtacg acgccaaaac tgctggctaa cgaaaccgac
    12061 gcgcgtttca ttggctacgg cgcaatgctg atggagtcct tcgtggcgat tatggcgctg
    12121 gttgcagcgt ccatcatcga accgggtctt tacttcgcga tgaatacccc gcctgctggc
    12181 cttggcatca ccatgcctaa cctgcatgaa atgggtggcg agaacgcgcc gatcatcatg
    12241 gcgcagctga aagacgttac cgcacacgcg gcagcgaccg tcagctcctg gggcttcgtg
    12301 atttcgccag agcagatcct gcaaaccgcg aaagacattg gtgagccttc tgtcctgaac
    12361 cgtgcaggtg gtgcgccaac gctggcggta ggtatcgctc acgtgttcca caaagtgctg
    12421 ccgatggctg acatgggctt ctggtatcac ttcggtattc tgttcgaagc cctgttcatc
    12481 ctgaccgcgc tggatgcggg tactcgttct ggccgcttta tgctgcaaga cctgctgggt
    12541 aacttcatcc cgttcctgaa aaaaaccgac tctctggttg ccggtatcat cggtactgcg
    12601 ggctgtgtgg gtctgtgggg ctacctgctg tatcagggcg tggtcgatcc gctgggcggc
    12661 gttaagagcc tgtggccgct gttcggtatt tccaaccaga tgctggcagc cgtagcgctg
    12721 gtactgggca ccgttgtgct gattaagatg aagcgcaccc aatacatctg ggtaactgtt
    12781 gttccggctg tatggctgct tatctgcacc acctgggcgc tgggtctgaa actgttcagc
    12841 accaacccgc agatggaagg cttcttctac atggcaagcc agtacaaaga gaagattgct
    12901 aacggtactg acctgacggc gcagcagatt gccaacatga accacatcgt tgtgaacaac
    12961 tacaccaacg cgggcctgag tattctgttc ctgattgtgg tgtacagcat catcttctac
    13021 ggtttcaaaa cctggcttgc ggtgcgtaac agcgacaaac gtactgacaa agaaacaccg
    13081 tacgttccaa tcccggaagg cggcgtgaag atctcttcgc accactaacc gtatttagcc
    13141 ccgcttcggc ggggctttgt tcttatcaga gtgaactatg tttggtaact taggacaggc
    13201 aaaaaaatat ctcggccagg cggcgaagat gttgattggc attccagact atgacaacta
    13261 cgtcgagcat atgaagacca accatcccga caagccgtac atgagctatg aagaattctt
    13321 ccgcgaacgc cagaacgcac gctacggcgg cgatggtaaa ggcggtatgc gctgttgtta
    13381 atggagagag catgaacccg attgcagtta ccctactcac cggtttttta ggcgcgggca
    13441 aaaccaccct gctgcgccat attcttaatg aacaacacgg ctacaagatt gccgtgattg
    13501 aaaacgaatt cggcgaagtc tccgttgatg atcaattgat tggtgatcgc gcaacgcaga
    13561 tcaaaacgct gaccaacggc tgcatctgct gttcgcgctc caacgagctg gaggacgcgc
    13621 tactcgacct gctggataat ctcgacaagg gcaatattca gttcgatcgt ctggtcattg
    13681 aatgcaccgg catggccgat cctggcccga ttattcaaac ctttttctcc catgagattt
    13741 tatgccagcg ctacctgctg gacggcgtga ttgcgctggt ggatgcggta catgccgatg
    13801 agcagatgaa ccagttcacc atcgcccagt cccaggtggg ctacgccgac cgtattctgc
    13861 tgactaaaac cgacgtcgca ggcgaagcag aaaaactgcg tgaacgcctg gcgcgcatca
    13921 acgcccgtgc accggtctac accgtcaccc acggcgacat cgacctgggc ctgctgttca
    13981 acaccaacgg ttttatgctg gaagaaaacg tcgtcagcac caaaccgcgt ttccacttta
    14041 tcgcggataa acaaaacgat atttcgtcga ttgtggtgga actggattac ccggtagata
    14101 tcagcgaagt ttcccgggtg atggaaaacc tgctgctgga atcggcggat aaactgctgc
    14161 gttacaaagg gatgctgtgg attgacggcg aacctaaccg cctgctgttc cagggcgtcc
    14221 agcgcctcta cagcgccgac tgggacaggc catggggcga tgaaacaccg catagcacga
    14281 tggtgtttat cgggattcag ttgccggagg atgagattcg ggcggcgttt gcgggactca
    14341 aaaagtaacc agccctccaa catcacaata cctgagactt tatcaccctc atattcctcc
    14401 agaatatgag ggctttcggg cttaattatc tctgaacgtg caacacttcc tgcgactcct
    14461 tatgcgcctc cacatcctgc ttcgttaacc agagcgactt acggccaaaa ttttcgtaca
    14521 ttttcagctg atcttcatag tgcttatcaa ctgttccatc gggagcaata aacccactct
    14581 gaccgggtgc gaccacatcc caggcaagca caggacgatc gcttgtcgtt ggtgagaaaa
    14641 caatcatatc gttttctgtt ccacggtttt gatactccgc ctgatgacgc gtttcttccg
    14701 ctgcggcctg cggtacacca aagaaattat ttgcccggaa cgttaaggcc attgcaggtg
    14761 ttttccagtt actcacatta ttgccatagc gtttggaaag agtctcccag gtatcttcca
    14821 gcgcagccaa cacaacctcc tgctgtggtt tcccagcaaa cagatcaacc gcctgtggga
    14881 ttggtgattt gtctccctgc accgcctcat acaaaatttt tgctccaaca cttatattca
    14941 gcgaaccagt tgggccgtcc tgggttgttt cgtagccact ggcgctgtac cacttatcaa
    15001 atggcatagg tacggcagcc actacggtac gcttcaacat actggtcagc caaacgttca
    15061 ggatggcaga gcctggctgc tgccaggttt taccatcatc attaagcaaa ttgatgccat
    15121 cccaacgtgt taatgtttct accaactgac gacgcggatc gctctgtgtc aaaccagatg
    15181 tcgctgcttg cagagtaggt aaaaaaagcc tcaggttaag atcctgacga ctggtttggc
    15241 gaataacatc ccatgcctga tcagcagtta agcgtggctt ttgctcaagc agtcggtcga
    15301 tctccgtaac gcgatctgca ccaccccaca aaaaggcaaa cagatctgaa gcgggataat
    15361 ctttttgggg agaattgttc cagttagcaa tatatcccga ctgggggtta tacaccttag
    15421 ggttcatttc aaaaggcaat agccctttcc agtcccattt tcccgtacca ggaacgggta
    15481 atcgcggatc atggcctgat tgacgatctg gataagcacc agtatgaaca taaccaatat
    15541 tgccgtttac atcagcatag taccagttga tggtcagtgc ttgtttcgct gcctgctgtg
    15601 tccactcctg ccaatttttg gccttcatct gatgagtcca ggccagcaaa gacgccacct
    15661 ctttaccatc ccatgcgcgg gatttagcgt aagccgtttg tgtcgtctgg tcagtttgga
    15721 gaatgttgcc atgcaccgta cgccagacag taaaggtctc tgcctgacca tttttcaccg
    15781 taatggtttc ctcacggctt aacattttca cccacttacc attatgcaag tagtagcctg
    15841 gtttctctgc cgacagccgt tcagcaaaaa tatcgacatc atcgccgaaa cctgccgttg
    15901 atccccagga aatcacacca ttatgaccaa aaaccagccc aggataggca aatggtgtat
    15961 tgccagtgac atcataacca gcaccgtgca gaccaatacc ataagtatac gcaggcgcat
    16021 accagccaaa ctgcggacca tttaccatga ttgctttcgc atcctgggct ttgcttttgc
    16081 cgatcaccca catattgctg gtcgttggat accccgccag accattggca ccaccctgtg
    16141 caaattgtgc agcaatagtt tcccggttct tccctgctgt taacgccagc agtgcgccat
    16201 ccgccccttt tgctggtcgg tcaagcattg gtgcaggtaa atcgtagcgt ggcaacagag
    16261 ctgctgtttg cgagttttgc tgattaaatt taagtgggta gttactctct tgtacggcaa
    16321 tagtggttgg cgctgatggg tttaccagcc atttcaactg attaaatacc gccatgcctt
    16381 gtgatacacc atatttatct tttaaagccg ttagcagtgc cagattatca atttcgctag
    16441 tgctatcaga gaagcggttt gccatggtgc ccacaaatat catcgcgaca tcaaacggtt
    16501 cccagcgctt aggagtaaag ccaaatgtat taaactgttt tggtaagagc gtctctggat
    16561 tggtatttac cttatcaatc caggcattca ttccatcagc gtagccttgc agaatggaca
    16621 tatcctctgg ggaaagggca gcaatttgcg cccggatagc atccggccag tagttacgac
    16681 ggatatcttt atcaaatttc acaaaatctt tgccaagcac ttccgcgaca gtcccttgag
    16741 tactgcgacg tgccatttcc atctgaaaaa ggcgatcttg tgctactaca tagccatagc
    16801 cataaaatag gtgccatgta tcattggcat aaatatgcgg catgccgtat tcatcgcgaa
    16861 caatctttat ctcacttgac gactgctcag ccagtgcagg taagctccaa taatacatca
    16921 gggaagcagt aacacagttc acgatcatac gatttctatt tttcattgta tcctctggca
    16981 ggtgtataat tagcgaattg atactagcaa cgaagcttcg gttatctatt tgcagagaat
    17041 tgtttcatta tgaactgtga gcgcgataac taatttttga tacaaaaatt tcattaatgt
    17101 gatctaaaac gaatcgcttt attcaccgct gatgattttg ttctattcct ttttgtgaca
    17161 gatcccccgg acgcatagat gatgaccccc agagagacag ctcaggtcat tatctgtatg
    17221 taaatcagaa aaatatgttg taaacgactt ttatggttgg attttgtagc aattttgaat
    17281 gcagacaggc agcatttgcc aacacgccgc ccatagttca ctccacatcc tccctgcgta
    17341 acccaatatc cctcaaccgt tcatcactca tctgctgtaa cactcgtcgg gtctgcattt
    17401 gccgccgcca acgcctcacc gcatgccaga gttgcacaag tctgataaac ggcgttttgg
    17461 ctttgttttc gtgaaattcc atctgctgcc tcctcatctt tcagaggctt catcatccgc
    17521 cttctggcag ttcacaatac agatgcaaat attagtttta tttaacatac agacaggtta
    17581 aaacagcatc tgcatccggt tttttagcct catctgtacc ggtttttctt tctgtatggg
    17641 ccaaataagg aatacagcat gacgcgttat caacatctgg cgactctact tgccgagcgg
    17701 attgagcaag ggctgtatcg tcacggggag aaattgccgt cggtgcgcag cttaagtcag
    17761 gagcacggcg tcagcatcag caccgtgcaa caggcgtatc agacgctgga aacgatgagg
    17821 ctcatcactc cgcagccgcg ttcgggttat tttgtcgcac aacgtaaagc ccagccgcct
    17881 gtaccgccga tgacgcgtcc ggtgcagcgc ccggtggaaa ttacccagtg ggatcaggtg
    17941 ctggatatgc tggaggcgca tagcgacaat tccattgttc cgttaagcaa aagcacgccg
    18001 gatgtcgaaa cgcccagcct gaaaccgctg tggcgtgagc taagccgggt ggtgcagcat
    18061 aatctgcaaa ccgttctcgg ttatgacttg ttagccggtc agcgagtgtt gcgggagcag
    18121 attgcccgcc tgatgctcga cagcggctcg gtggtcaccg ccgatgacat catcatcacc
    18181 agcggctgcc ataactcgat gtcgctggcg ttaatggcgg tgtgtaaacc gggcgatatt
    18241 gtcgcggtcg aatctccctg ttattacggt tcgatgcaga tgctgcgagg catgggcgtg
    18301 aaagtgattg aaatcccaac cgatccagaa actggcatca gcgttgaagc actggaactg
    18361 gcgctggaac agtggccgat taaaggcatc attctggtgc caaactgtaa taatccgctg
    18421 ggatttatta tgccggacgc acgcaaacgg gccgttctct ctctcgctca gcgtcatgat
    18481 attgtgattt ttgaagatga tgtctacggc gaactggcaa cggagtatcc gcgcccgcgg
    18541 accatccatt catgggatat cgacgggcga gtgctgttgt gcagctcgtt cagtaaaagt
    18601 attgctccag gcctgcgcgt gggttgggtc gcaccggggc gttatcacga taaactgatg
    18661 catatgaaat acgccatcag cagctttaat gtgccgtcca cgcaaatggc ggcggcaacg
    18721 tttgtgttgg aaggccacta tcatcgccat atccggcgga tgcggcagac ttatcagcgc
    18781 aatctggcgc tttatacctg ctggatacgg gaatattttc cctgcgaaat ctgtattacg
    18841 cgcccgaaag gcggattttt actgtggata gaattgcctg aacaggtcga tatggtctgc
    18901 gttgcgcggc agctgtgccg catgaatatc caggtggcag caggctcgat tttctcggct
    18961 tccggcaaat accgtaattg tctacgcatc aactgcgctt tgccgctcag cgaaacctat
    19021 cgcgaagcac taaagcaaat tggcgaggcc gtgtatcggg caatggaata aattcgaatt
    19081 agtggcgaag cacctgattt cctctcacga atcgcctgta actcgttgta tctttgcagg
    19141 gtcatcgcca cgttccagca tggcttaggc aaagtgtgct tcgttcatac cggatgcggc
    19201 gtgaacgcct tatccggcct acaaaccgcg caaattcaat agattgcaga ggaaatgtag
    19261 gtctgataag cgtagcgcat caggcagctt tgcgtttgtc atccgtctct gattagtatt
    19321 cgatccatgg atcgcgcttg atttcaggca agggctgctc taatgcctgc atttgctctg
    19381 tcgaaagtcc ggtaatcttt tgtatccatt caggatctgc cccattctgc aacaacaatc
    19441 taaggaggcg ttgttcccct tcttctttcc ccttttccat ccccaacagc catccatcat
    19501 tataaattcg ctctgcaatc gtcattattc gctccctgtg ttgtggcatt cgacgggtaa
    19561 gttcgctgat aaacgcctta aaacgcgctt catcgccagt cagtaaaatg taatttaaca
    19621 gcgcagttat ctggctgtca ttagcacact ctgtaaccag taatactacc agttggtcaa
    19681 taagccccat cagatcgcgc tggcgaatat gcttttggat caactccaac agggcgactc
    19741 tgcgatgctg cacaatctcg tcgtctggca cgacagtgac atccaccagc gggaacgctg
    19801 cgctataaag tttccgtgcg gtagtcgggg cggcaaattc gtccagccag cacagggacc
    19861 aggggtaagg actacggcta ccgtgataaa acagcatcgg gataaccagc ggtagcggcc
    19921 ggcgtttatc atgctcgata tggcgctgca tcaccgccat ggaatatcgc atcaggcgaa
    19981 acgccatatg aatatcctcg cggctctgat gttcaatcac tacgtaaata taaccatcac
    20041 cttcacgggt ctttaccgac cacagaatat cggagtgtag cgcccgcaat ttttcatcga
    20101 caaagctggc ggattccagt tttaagctgt cgagatcgca cagttcacgt aaatctttag
    20161 gtaagtggat ctccataaaa tcccgcgcgg tgccagggtg cgtgagaaag gacttaaata
    20221 atgcgtcatg cggcgtgctg gtcgagaagt ttgtcatggc gatccgtcac ctgtagataa
    20281 gatggcccga ctttagcggc taacaaaacc attctcaccc ggcaatttcc cgttccccga
    20341 ggcgctttcc aggctatttt tattcttctg caaacgatac attttttcgg aaacaggctc
    20401 gcgttttaca tttcctgtac ccggcagata ttcccctttc caccgcgctc ttttgattaa
    20461 ccgcaaattt taattacact taaggtgtat attttctatg caacccatca attaaagagg
    20521 tgtaatgtgc tgatgactat ttgtaatcgt tatacattct gacctggagt cagaaggtat
    20581 ttctctgtct gtgtgttcac aggcagtgtg gttgattaca tgaaattcag tacatttgtc
    20641 cttctcgcct gcctttcgtc attaccgacg gtattgaatt tcgttttccc cgttggggtt
    20701 ctccggacaa ggagttgttt gttatgccac gtttttttgc ccgccatgcc gccacgctgt
    20761 ttttcccgat ggcgttgatt ttgtatgact ttgccgcgta cctgtcgacg gatctgatcc
    20821 agccggggat cattaatgtg gtcggtgatt ttaatgccga tgtcagtctg gccccggcag
    20881 ccgtcagtct ctatctcgcg ggcggtatgg cgttacagtg gctgctgggg ccgctttccg
    20941 acaggattgg ccgcaggccg gtgctgatta ccggggcgct aatatttacc cttgcctgcg
    21001 ctgcgacaat gttcacaacg tctatgacac agtttcttat cgcgcgtgca attcagggca
    21061 ccagtatctg ttttattgcc accgttggtt atgtcacggt gcaggaggcg ttcggccaga
    21121 caaaagggat caagttgatg gcgattatca cctccatcgt actgattgcg ccgattattg
    21181 gcccgctttc cggcgcagct ctgatgcact ttgtgcactg gaaagtcctt tttgccatca
    21241 ttgcagttat gggttttatc tcatttgttg gcttactgct ggcgatgcca gagacggtga
    21301 agcgcggcgc ggttccattt agcgccaaaa gcgtctttcg cgattttcgt aatgtctttt
    21361 gcaatcggct gttcctcttt ggcgcagcaa ccatctcttt aagctatatc ccaatgatga
    21421 gttgggtggc tgtctcgccg gtgatcctga tcgacgcggg cggcttaaca acttcgcagt
    21481 tcgcctggac acaggttccg gtgttcggcg cggtgattgt cgcgaatgcc atcgtggcgc
    21541 gtttcgttaa agatccgacc gaatcgcgct ttatctggcg tgctgtaccc attcaactgg
    21601 tcggcctcgc actgttgatt atcggcaatc tgctgtcacc gcacgtctgg ctgtggtcgg
    21661 tgctgggcac cagtttgtat gctttcggga ttggtttgat cttcccgacc ttattccgct
    21721 ttacgctttt ttccaataac ttaccgaaag ggaccgtctc cgcatcgctg aatatggtga
    21781 tcctgatggt gatgtctgtc tcggtcgaaa tcggccgctg gctgtggttt aacggcggtc
    21841 gcttgccgtt tcatctgtta gccgtcgtgg cgggcgttat cgtcgttttc accctggcag
    21901 gattgcttaa tcgcgtgcgc caacatcagg ctgccgagct ggcggaggag cggtgatttt
    21961 tgcgcgatcc tgccgtcagg ctctattctt aacgttatga ataaactcat tgaactcaga
    22021 cgcgccaaaa tgttggcgct ctctttactg cttatcgccg ctgctacctt tgtcgttacg
    22081 ctgtttttgc cgcccaattt ttgggtgagc ggcgtgaagg cgattgctga agcggcgatg
    22141 gtcggcgcgc tggcggactg gtttgcggtg gtggcgctgt ttcgccgcgt gccgattccg
    22201 atcatttctc gtcatacggc gattatcccg cgtaataaag accggattgg cgaaaatctc
    22261 ggccagttcg tgcaggaaaa atttctcgat acccagtcgc tggtggcatt gattcgacgt
    22321 cacgaaccgg cgttgctgat tggcaactgg tttagccagc cagaaaacgc ccgccgcgtt
    22381 ggtcagcatc tgttgcagat catgagtggt tttcttgaac tgaccgatga tgcgcgtatt
    22441 cagcgcctgc ttaagcgcgc ggtccatcgg gcgattgata aggtcgatct ttccggaacc
    22501 agtgcgttga tgctggagag tatgaccaaa aacgatcgtc atcaggtgct gctcgatacg
    22561 ctgatcgcac agttgatcgc ccttctccag cgcgataaat cgcgcaagtt tattgcccag
    22621 cagattgttc gctggctgga gagtgagcat ccactgaaag ccaaaattct ccccaccgaa
    22681 tggttgggcg aacatagcgc ggagttggtt tctgacgcgg tgaattcttt acttgatgat
    22741 atcagccgtg atcgtgcgca tcagatccgt catgcgtttg atcgcgccac ttttgccctg
    22801 atcgacaagt tgaaaaacga tccggaaatg gcagcgcgag ccgatgccgt aaaaagttat
    22861 ctgaaagaag atgaagcttt taaccgctat ctcagtgaat tgtgggggga tttacgggag
    22921 tggctgaaag cggatatcaa cagtgaagat tctcgtgtga aagaacgtat cgcgcgggcg
    22981 ggtcaatggt ttggcgaaac gttaattgcc gatgatgcct tgcgggcgtc gttaaatggt
    23041 cacctggaac aagccgcgca ccgcgtcgcg cctgagtttt ccgcattcct gacgcgccac
    23101 atcagcgata cagtaaaaag ctgggatgcg cgggatatgt cgcggcaaat cgagttaaat
    23161 atcggcaaag atctgcagtt tatccgtgtc aacggtacgc tggttggcgg ttgtattggg
    23221 ctaattttat atttgttgtc gcagctcccg gccttgttcc ccctcggcaa tttttagaaa
    23281 tccatgaaca actaagtggc taaccgcgag agagatcaaa taaaccacac taaaagaatg
    23341 gtaataatgt ggcctctttt cattatctcc cgtggtacgg ggaaggaaaa tcatgtcact
    23401 tatcaccgat ctacccgcca ttttcgatca gttctctgaa gctcgccaga aaggctttct
    23461 caccgtcatg gatctcaagg agcgcggcat tccgctggtt ggcacttact gcacctttat
    23521 gccgcaagag atcccgatgg cagccggtgc ggttgtggtt tcgctctgtt ctacctctga
    23581 tgaaaccatt gaagaagcgg agaaagatct gccgcgcaac ctctgcccgc tgattaaaag
    23641 cagctacggc ttcggcaaaa ccgataaatg cccctacttc tacttttcgg atctggtggt
    23701 cggtgaaacc acctgcgacg gcaaaaagaa aatgtatgaa tacatggcgg agtttaagcc
    23761 cgttcatgtg atgcagttgc cgaacagcgt taaggacgat gcctcgcgtg cgttatggaa
    23821 agccgagatg ctgcgcttgc aaaaaacggt agaagaacgt tttgggcacg agattagcga
    23881 agatgctctg cgcgatgcca ttgcgctgaa aaaccgcgaa cgtcgcgcac tggctaattt
    23941 ttatcatctt gggcagttaa atcctccggc gcttagcggc agcgacattc tgaaagtggt
    24001 ctacggcgca accttccggt tcgataaaga ggcgttgatc aatgaactgg acgcgatgac
    24061 agcccgcgtt cgtcagcagt gggaagaagg ccagcggctg gccctgcgtc cacgcatttt
    24121 aatcaccggc tgcccgattg gcggcgcagc agaaaaagtg gtgcgcgcga ttgaagagaa
    24181 tggcggctgg gttgtcggtt atgaaaactg caccggggcg aaagcgaccg agcaatgcgt
    24241 ggcagaaacg ggcgatgtct acgacgcact ggcggataaa tatctggcga ttggctgctc
    24301 ctgtgtttcg ccgaacgatc agcgcctgca aatgctcagc cagatggtgg aagaatatca
    24361 ggtcgatggc gtagttgatg tgattttgca ggcgtgccat acctacgcgg tggaatcgct
    24421 ggcgattaaa cgtcatgtgc gtcagcagca caacattccc tatatcgcta ttgaaacaga
    24481 ctactccacc tcagatgtcg ggcagctcag tacccgtgtc gcggccttta ttgagatgct
    24541 gtaaggagtg gcagtgacat attcgattgg cattgattct ggttctaccg ccaccaaagg
    24601 gatcttactg gcagacggcg tgattacgcg ccgtttcctc gttccaacac cctttcgtcc
    24661 ggcaacagca attactgaag cctgggaaac tctgcgcgaa gggttagaga caacgccgtt
    24721 tctgacgctc accggctatg gacggcaact ggtggatttt gccgataaac aagtgacgga
    24781 aatctcctgt catgggctgg gcgcacggtt tcttgcgcca gcaacgcgcg cggtaatcga
    24841 catcggtggt caggacagca aagtgattca gcttgatgat gacggtaacc tgtgcgattt
    24901 cctgatgaat gacaaatgcg cggcgggcac cgggcgtttc ctggaggtga tctcgcgcac
    24961 gcttggcacc agcgtcgagc aactcgacag cattaccgaa aatgtcacgc cgcacgccat
    25021 cacgagtatg tgcacagtgt ttgccgaatc agaagtgatc agcctgcgct cagcgggcgt
    25081 cgcgccagaa gcgattctcg ccggagtgat taacgcgatg gcgcggagga gtgccaattt
    25141 cattgctcgt ctctcctgtg aagcgccgat tctgtttact ggtggcgtta gtcattgcca
    25201 gacgtttgcc cggatgctgg aatctcatct gggaatgccg gtaaataccc atcctgatgc
    25261 gcaatttgct ggcgcaattg gcgcggcggt aattggtcaa cgagtgagga cacgccgatg
    25321 aaagagtttt tatttttatt tcactccacg gtcggcgtca tacaaacccg caaggcgttg
    25381 caggcagcgg gcatgacttt tcgcgtcagc gatattcccc gtgatttacg cggcggctgc
    25441 gggttatgca tttggctgac ctgtcccccc ggcgaggaaa tacaatgggt gatccctggg
    25501 cagactgagt caatttattg ccagcaggat ggtgtctggc gctgcattgc acattacggg
    25561 gtttctccgc gttaaggatt cattaaggtc gctacgtata cttctcgata tcttattgat
    25621 ttgccttaaa gggattaccg tgacaaaaag tatttcgtta agtaaacgca tctccgttat
    25681 tgtgattctt tttgccattg tggcagtgtg tactttcttc gtgcaatctt gcgcccgtaa
    25741 aagcaatcat gcagcatcat ttcagaatta ccacgccacc attgacggca aagaaattgc
    25801 aggcataacg aataatatct cttcgctgac ctggtcggca caaagcaata ctctttttag
    25861 cactatcaac aaacctgccg ccattgttga aatgaccacc aatggtgatt ttatccgcac
    25921 aattcctctg gattttgtta aggatctcga gacgatcgaa tacattggcg ataatcagtt
    25981 tgtcattagc gatgagcgcg attacgccat ttatgtgatt tcactgaccc caaactcgga
    26041 agtaaaaatc ctcaaaaaaa taaaaatccc gctgcaagac tccccaacca attgcggttt
    26101 tgaagggttg gcttattctc gccaggatca cactttctgg ttttttaaag agaaaaatcc
    26161 gattgaggtc tacaaagtta acgggctgtt aagtagcaat gaattacaca tcagcaaaga
    26221 cgaggcacta caacggcaat ttactttaga tgatgtgtcc ggcgcagaat ttaaccagca
    26281 aaaaaatacg cttctggtgc tatctcatga atctcgcgca ctccaggaag taaccctggt
    26341 tggcgaggtt atcggtgaaa tatcactaac caaaggtagt cgaggtttgt cgcataacat
    26401 caaacaggcc gaagggattg cgatggatgc ctctggtaat atttatatcg ttagcgaacc
    26461 aaatcgtttt tatcgcttta cccctaaatc atcgcattaa caggctggca tatttcacct
    26521 ttttgttatt aacttgttaa caacaaaaat gacatacaag gttaaacatg ccttcgtcct
    26581 cgcatcccgt agaacgcttt tctttcagca ccgcgctttt cgggatgctg gttctgacct
    26641 taggtatggg attaggtcgc ttcctttata cgcctatgtt gcccgtcatg atggcggaag
    26701 gggcgttttc atttagccag ctctcgtgga ttgccagcgg caactatgcg gggtatctgg
    26761 ctggcagtct gctattttcg tttggcgcat ttcaccagcc gtcgcgcctg cgcccattac
    26821 tgttggtttc tgccctggcg agcgggttgt tgatcctcgc aatggcatgg ttgccgccat
    26881 ttattctggt gttattgatt cgcttcctgg cgggtgtcgc cagcgccggt atgctgattt
    26941 ttggttcgac gctgattatg cagcacacgc gccatccttt tgtgctggca gctttgtttt
    27001 ctggcgttgg cattggcatt gcactgggca acgaatatgt tctggcaggc ctgcattttg
    27061 ccttctcctc gcaaacgtta tggcaaggcg ccggggcgct ttctggcatg atgctgattg
    27121 cacttacgct tttaatgccc tcgaaaaaac acgccatcgc accaatgcca ttggcaaaaa
    27181 cggagcaaca gataatgagc tggtggttac tggctattct gtacggcctt gcgggatttg
    27241 gttatatcat cgtcgcgact tacctgccgc tcatggcgaa agatgcaggc tcaccattgt
    27301 taaccgccca tctctggacg ttagtcggct tatcaattgt gccaggctgc tttggctggc
    27361 tatgggcagc aaaacgttgg ggggctttgc cttgcctgac ggcgaatttg ctggtgcagg
    27421 ctatcagtgt gctgcttact ctcgccagcg actctcctct cttgcttatc attagtagta
    27481 tcggttttgg cggtaccttt atgggcacga catctctggt gatgactatc gcccgccaac
    27541 tgagcgttcc gggaaatctc aatcttttag gctttgtgac gctcatttac ggcattggac
    27601 aaatcctcgg cccggcgctg accagtatgc tcggcaatgg aacatcggcg cttgccggcg
    27661 ccactctctg cggcgcggcg gcgttgttta ttgctgcgct tatcagcaca gtacaattat
    27721 ttaagctgca agtggtcact tcatgaggag tgtttccctt accactcaag aaactcaaca
    27781 gcaaccgttg atgtcagcca gaccccgttt tccgcttgcc agaaagggat gcctcgtttc
    27841 gccatttcct gtgctttgac ggttaagata accggcgatc cgtgtcttgc tcccactttg
    27901 cgtgccgttg cttcatcagc agagagatgt acgtaatgac gctcccctgc aatcagcccc
    27961 tgttttttta tctcgtcaag gaaacggctt gccgtaccgt ggtagagaaa ctgtggcggt
    28021 gttttttcgg caaaggaaat ggcgacctgc gaagtcgaat gcccctgaac cgcgcggatg
    28081 cacctaccat cactggaata actaaaacgc tttttatcgc tggtggcaac cacagtatcc
    28141 agcaatgcac gggttaaccg cttgcccgct ttttgggcac aaagtatgag cttatcgata
    28201 tccgcccatc cttcacggtc aagtacgata ccaatcgcct ccggtttgtg tcggaggaca
    28261 aaacttaaaa acttgctcgt atccgccaac tctttttcgt tgtactttgc catcgcgttt
    28321 tcgtccctgg attttctgtt tttatttact gatgtcattg tcactgggtt tatgaatttt
    28381 ctgcaactca atcctgcgca gagccttttc tacacagcgt aatttttccg ctatgcaaaa
    28441 aacgcatagc aagaaacata cttgcatttt ccccataccc acatggctga taaggttttt
    28501 cagctccagg aattttcctg gctcaagcaa cacacaaaca caaaaaaaca atggggattg
    28561 ttatgacaca acaaggggat gctgtagccg gggagctggc gacagaaaaa gtgggcatta
    28621 aagggtatct ggcttttttt ctcaccataa tctttttttc cggagttttt tccgggacag
    28681 acagctggtg gcgcgttttt gatttttccg ttctgaacgg atcgtttggg caactgcctg
    28741 gtgcgaatgg agccaccacc tcatttcgcg gggcgggtgg cgcgggggct aaagatggct
    28801 ttctctttgc gctggagctg gcaccgtcag tcattctctc tctggggatt atttcaatta
    28861 ccgatggtct tggtggatta cgcgccgcgc agcagttaat gacgcctgtg ctaaaaccgt
    28921 tgttgggcat tccagggatc tgctcgctgg cgctgatcgc taacctgcaa aacactgatg
    28981 ccgccgccgg tatgaccaaa gagctggcgc aggaagggga aatgaccgaa cgcgataaag
    29041 tgattttcgc cgcatatcaa accagcggta gcgccatcat caccaactac ttctcttccg
    29101 gcgtcgcggt gttcgccttt ctgggcacgt ccgtaatcgt acctttagcc gtcatcctgg
    29161 tgtttaaatt tgtcggagcc aacattttgc gcgtctggct taacttcgaa gaacgtcgca
    29221 acccaacgca aggagcgcaa gcatgacaac tcaggtccgc aaaaacgtca tggatatgtt
    29281 tatcgatggc gcgcgccgtg gctttactat cgccacgacc aacctgctgc caaacgtggt
    29341 gatggcgttt gtcatcattc aggcgctgaa aattaccggc ctgctcgact gggtggggca
    29401 tatctgtgaa cccgtaatgg cgctgtgggg attacccggt gaagcggcaa ccgtcctttt
    29461 agccgcatta atgagtatgg gcggcgcagt cggtgttgcc gccagtctgg cgaccgccgg
    29521 cgcattaacc ggtcacgatg tcaccgtttt actgcccgcg atgtatttaa taggcaaccc
    29581 ggtgcaaaat gtcggtcgct gcctggggac agccgaagtg aatgccaaat attacccgca
    29641 tatcattacg gtctgcgtga ttaacgcatt gctgtcgatc tgggttatgc agcttattgt
    29701 ttaacaagga gttaccatga ttgattatac cgcagccggt tttaccctgc tgcagggagc
    29761 gcatttgtat gcgccggaag atcggggaat ttgcgatgtc ctcgtcgcta acggcaaaat
    29821 tatcgccgtt gccagcaata tcccttctga cattgtaccg gactgcacgg ttgtcgatct
    29881 cagcgggcag atcctctgtc ctggttttat tgatcaacac gtccatttga ttggtggtgg
    29941 cggcgaagca ggtcccacga cgcgcacgcc ggaagtggcg ctaagtcgcc tgacggaagc
    30001 gggcgtcacg tcagtggttg gtctgctggg caccgactct atctctcgcc acccggaatc
    30061 cctgctcgcc aagacccgtg cgctcaatga agaaggcatc agcgcctgga tgctgaccgg
    30121 cgcttatcat gtcccttccc gcaccattac gggttccgtg gaaaaagacg tggcgattat
    30181 cgatcgtgtg attggcgtga aatgcgccat ctctgatcac cgttctgccg caccggacgt
    30241 ttatcacctg gccaatatgg cggcagaatc ccgcgttggc ggtttgctcg gcggtaaacc
    30301 tggcgtcacc gtgttccaca tgggcgacag taaaaaggcg ttacagccta tttatgacct
    30361 gctggaaaac tgcgatgtgc cgatcagcaa gctgctgccg acccacgtta accgcaacgt
    30421 accgttgttt gagcaggcgc tggagttcgc gcgcaaaggc ggcaccatcg atatcaccag
    30481 cagcattgac gaaccggtcg cccctgccga aggtattgcc cgcgccgttc aggcgggtat
    30541 tccgctggca cgcgtcaccc tcagctccga cggcaacggt agccagccgt tcttcgatga
    30601 cgaagggaat ttaacccata tcggtgttgc aggttttgaa acgttgctgg aaaccgtgca
    30661 ggtgctggtc aaagactatg atttcagtat cagcgatgcc ctgcgcccgc tcaccagtag
    30721 cgtagccggt ttccttaacc tgaccgggaa aggtgaaatt ctgccaggca atgatgctga
    30781 cttgctggtc atgacgccag aactgcgcat tgagcaggta tacgctcgcg gcaaactgat
    30841 ggtcaaagac ggcaaagcct gcgtgaaagg aacgtttgaa acggcttaaa cggttgtcag
    30901 ccgcccgaat ggacgtagaa tgcccgcaag ggcggctgac agagtaaaac gtaatggatg
    30961 actgtggtgc gattttgcat aatattgaaa ccaaatggct ttatgatttt ctgaccctgg
    31021 aaaaatgccg caatttttcc caggcggcag tcagtcgcaa cgtctcgcaa ccggcattca
    31081 gccgccgcat ccgtgcgctg gaacaggcga ttggtgttga attgtttaac cgccaggtaa
    31141 cgccgctgca actctcagaa caagggaaaa tcttccattc gcagatccgc catctgttgc
    31201 aacagttaga gagcaatctg gcagagctgc gtggcggcag cgattacgcg caacgtaaaa
    31261 tcaagatagc cgctgcacac tctctttccc tcggtctgtt accgtccatt atcagccaga
    31321 tgccgccgct ctttacctgg gcaattgaag ccattgatgt cgatgaagcg gtcgataaac
    31381 tgcgtgaagg gcaaagtgac tgtatttttt cctttcacga cgaagatttg ctggaagcgc
    31441 cgtttgacca cattcgctta tttgaatctc aattgttccc tgtctgcgcc agtgacgaac
    31501 acggagaagc actttttaac ctcgcgcagc cacactttcc gttactgaat tacagccgca
    31561 actcctacat ggggcgattg attaatcgca ccctgacgcg ccacagtgag ttaagtttca
    31621 gcaccttttt tgtctcttcg atgagcgagc ttttaaagca ggttgccctc gacggctgtg
    31681 ggattgcctg gctgccggag tacgccatcc aacaagaaat tcgcagcggg aagctcgttg
    31741 tactgaatcg ggacgaactg gtgatcccga ttcaggccta tgcataccgg atgaataccc
    31801 gcatgaatcc cgttgccgaa cgcttctggc gtgaactgcg cgagctggag attgtgctta
    31861 gctgacattc tccagcgtcg cactgcgcca accgccatta tcccagacca gatcaaacgt
    31921 tagcggttca tcgtcgtggt acagcattat ctcaaggctg atcgccagag tgtggcagta
    31981 cgcttctttc agattaacct gcaacgccgc aatccgtggc tcatgaaata acagtgcaga
    32041 acgcagctga cggcaatacc agctctggag atgtttgtcg ctcgggttat gcacttgcca
    32101 ctcgggcatg cctgaaacaa gtaatgacgg taatgccgaa tgaggagaat taaaaagagt
    32161 gaggagatcg ctgcataccg atttacgcag caatgacgtt ttattgcctg aaatttcagg
    32221 taaaacagcc tgaagtgatt ggcgcatcat tttgcgcact cctgacgttt agcaacatat
    32281 gcggcttgcc ctgaacaccg ggcaccactg tattgatgct cattttccat agccattccc
    32341 ttttgttcat tacatccatg tcagtctgag acaggcctga atcctgtcag caaagtataa
    32401 aaccttactt gcctatgaat atctactgac ttttcaggaa aaaagtcatg atttgataaa
    32461 aatcatcaaa ctcaaaaaaa aaccgctagt atattctgaa tattccgaat agttatgtag
    32521 atgaaaatac ttgtcaccgc cgctacttaa ttccggtggg aaattattta tttccgcata
    32581 atcagccatg tattatttga aacaattagt ttgtaaataa tataaattga taacatatca
    32641 aatacatcaa aaataccatt cacaggcatt attaatatag acatcaatat agcaacatca
    32701 aattccaatt agtaataaga tatgcttttt aattgcatgc aaataatttt aaatgagcgt
    32761 tttttgatac tttagagtgt ttcctaccct ttaatatcac catgtagggt tgatatcact
    32821 acaacagaaa catgcatgtc atttgtttac ttctttttta ctacagaaaa atttatctat
    32881 ttttctaaac atcagtgaaa tactcataaa aagtaactat tatgtctatg ccattaagca
    32941 atgcccttca gagtcaaatt attacagata atcacttcct tcatcatcca aaagtcgaca
    33001 gtgagttaac acgtaaatat gaacgtgcac gcctggataa ggaaaatatc tatcttctgc
    33061 ctcttgctcg tggcaataac cataattacg atggaaaaag cgttgtcgaa attagaaaac
    33121 ttgatattag taaagagccc tggccattta attatgtgac agaaacatgc agagaatccg
    33181 atggtattac aacaacagga cgtatgctct atcgaaactt gaaaatcacc tcagctttag
    33241 acgaaatata tggtggtata tgtaaaaagg cgcatgctgc cacagagtta gcagaaggat
    33301 tacggctaag tttatttatg aagagccctt cctatcctgt tgaggactat acagttcatg
    33361 aaataacatt aggccctggt tgcaatgttc caggttacgc cggaaccacg ataggatata
    33421 tttcaacact tccagtttct caggcaaaaa gatggaccaa tgagcaacca aggattgata
    33481 tctatattga tcagataatg actgtctcag gggtggcaaa ctcttccgga ttcgcccttg
    33541 ccgcattact taatgctaat attgagttgg gtaatgaccc aataattggt atagaagcct
    33601 atcccggtac cgcggagatc catgcaaaaa tgggatataa agttatcccg ggtgatgaaa
    33661 atgcaccact caaacgtatg actctgcaac cgtcatctct tccagaactg tttgaattaa
    33721 aaaatggtga atggaattat attggtaaat agccactgag aagaatgagt actaacattc
    33781 aggttataca gatagctaaa caataccctg caatttacaa agtaatactc attgcgactt
    33841 cttaatttaa gaaagcgcaa ggaacgttta cccttgcgct tattataata agtcaggcgt
    33901 cgactttatc cagcggccat gaatcaaaca gatagccatc aaaataaata tcgtcaacgt
    33961 tcgagaattc cagcagacgt tgcttaacgt tttccagatg ctgccacatt gccagcttcg
    34021 ccgctcgggc atcttttttg attaacgcgg cgaggatctg tttgtgatcg cccaaccact
    34081 ctttgcgata caggctgtca tccagatggc tgtgcaactg gatccacatt ggattgtttt
    34141 cccgccactg ccaggactga cggaacagct ccaccagcat gctgttatgc gttgcttcgg
    34201 caatagcgag atggaactgc atgtcaccgc tttcgctgct gcccggcgca ctggaagcca
    34261 gttcacgctc ttccagttgc aatgcctgac gcattttgac gatatcttcg cgggtagcct
    34321 gcaaagcggc aaactcggcg atgttgctct ccaataactg ccgcgcctgt aacagctcaa
    34381 aaggaccggc atcgttgcag acgttggcat ccggactgtc tgtgttctgg ctgcctgagt
    34441 tatcaagaac atagataccg gcaccccggc gtacttccac cagccctttg atctccagca
    34501 tgatcagcgc ttcacgtacc accgtccgcg tgacatcaag catttctgca atttcacgct
    34561 ccggcggcag ccgttcgcca ggattgtacg gcgtctttat gatcagatcg cggatcatcg
    34621 ccccgacttc ctggtaaggt ctttgcgcag aggtggcaga tttcatggtg ttgtgtccgt
    34681 taggtgcggt taatcaaatt tttgccggat gcggcgtgaa cgccttatcc ggcctacaac
    34741 gggcaatttt acggcccccg ttaatctcaa actataccat tagcactgga agttggcacg
    34801 tataggtggg caaaaaaacg aaaactggtc aaccaaatat cagtttgatt gaccagtgag
    34861 tctgtagggt aatcagttag ttacagcgca gccacacact cgcgcgcacc gcgttcgcac
    34921 agctgctgat atgccgccgt cactgcgcca acaaagtcgg cattctgcgg cagatcatcg
    34981 gcaaaaatac cgctcaggcc cagcagcgct ttcacgcggt ctgcgccctg atactgcgcg
    35041 ttgaccttct ggaactccgc cagcatcggg tcgaccacgt caatggcatt accctgctca
    35101 tccacgccct gggtgtaacg catccagcca gccacgccca gcgccaggtg acgccagctg
    35161 ccgccgtttt gcaggtgcag acgcaccggg tccagcagac gctgcggtaa cttctggctg
    35221 ccgtccatcg caatctgcca ggtacggtga cgcagagacg ggttgctgaa acgctcgatc
    35281 agcagcgtcg cataggcgtt caggtccgta ccttccggca tcgacagcgt tggcgcttgt
    35341 tcctgcatca tcaaggagaa ggccgctttg cgataatccg ggttagtcat ggtgtcggca
    35401 atggtttcat agccgccgag gtaaccgagg tatgccagga aagagtggct gccgttcagc
    35461 atacgcagct tcatcatttc gaacggcaca acgtctgcaa cgaactgtgc gcccacttta
    35521 tcccagtccg ggcgaccgtt aacgaagtta tcttcaatca cccactgacg gaacggttcg
    35581 caggcaatgg cgcacgggtc gtaaacaccc agctggtcag caatttcctg caaggtttct
    35641 ggcgtcgccg ccggaacgat gcggtcaacc atggtgcacg ggaaggtgac gttttcttca
    35701 atccatgccg ccagctgcgg gtcacgcgcc tgagccagtc ccagtaccgc gaccttcgcc
    35761 acatggccgt tttcacgcac gttatcgcag gacatcaccg taaacgcttt caaccctttt
    35821 tcacgacgca gccgcagggc ttcgacgatg taaccaatcg cggacttcgg cgcagtcggg
    35881 ttttccagat cgtgcttgat cagtgggtta ttgagatcca gctgaccgct tgccgcatca
    35941 gcgcagtagc ctttttccgt gactgtcaga gagacaatcg ccgtctgcgg acgcgccatc
    36001 gcattgagaa taccttcgca gccgtcgatt tccggatgca gcgcttcttt catcgaaccg
    36061 ataattttca gctcggtgct ctctgcgcct ttttccgcta cggtgtacag cagttgctgt
    36121 tttttcaggt tttcgatcag cacgcggtcg ttgcctggca tcaggttaac ttcgcagatg
    36181 ccccagtcgc tgtcggtgct ttccagcaga tgatgggtat acagcgcctg gtgcgcgcgg
    36241 tgaaacgccc cgcaaccgag atgcacaatg cgtgattcca gacgagaatg atcccatgac
    36301 gggcgggcaa ccggcagatt gctgtcaaca atagtagtca tcgtaaactc cagaatccgt
    36361 cttcaaagag tgacggcaag gaagaaggaa ccggcacggc gcgcagccat gccggtggat
    36421 attaacggct aaagaaagcg cgctggatcg ccagttcgac accgcgaact tcggccaggc
    36481 ctttcagacg accaattgcg gagtaacctg ggttggtttt cttcttcagg tcgtccagca
    36541 tctgatgacc gtggtccgga cgcatcggga tcaggtcttc tttgccttcc gctttacgac
    36601 ggtgttcttc ttcaacaatc gctttcacca cttcgtacat atcaacgtca ccgttcaggt
    36661 gcgccgcttc gtggaaggtt ttcgggttat cttcacgcat ggtggagcgc agatgggtga
    36721 agtaaatacg cggaccgaac tgcttgatca tatcaaccag atcgttgtca gcacgcacgc
    36781 cgtaggaacc ggtgcacatg gtgaaaccgt tcgccatgct gtttacggta tcaaccatcc
    36841 actgcatatc ttcaatggtg gaaacaatgc gcggcaggcc gaggatcggg cgcggcggat
    36901 cgtccgggtg aacagccata cggacgccaa cttcttcggc aaccggaata atcgctttca
    36961 ggaagacagc aaagttttcg cgcagtttgg ctttgtcgat atctttgtac agctccaggt
    37021 gcttacggaa ctggtcgagg gtgtaccctt cttccgcacc tggcagacca gcgatgatgt
    37081 tacgggtcag acgcgctttg tcttcatcgc tcatggtggc gaagcgaaca gcagcctgag
    37141 caatttcttc ttcggtgtaa tccgcttccg cgcctggacg tttcaggata tgcatttcga
    37201 atgcagcgaa ttcgatctgg tcgaagcgca gagctttgga gccgtctggc agcacgtatt
    37261 cgaggtcagt acgggtccag tcgagcaccg gcatgaagtt gtagcacacg gtgcgaatgc
    37321 cgcactgcgc caggttgcgc agagtctgct gatagttagc gatccactgc tcatagttgc
    37381 cagtgtgggt tttgatatct tcgtgaattg gtacgctttc tacgacagac cacaccaggc
    37441 ctgcgtcttc aacgatcgcc ttgcgtttga ggatctcttc tacggaccat acttcgccgt
    37501 tcgggatatg gtgcagcgcg gtaaccacgc cagttgcgcc cgcctgacgg acatcagcta
    37561 aagaaaccgg atcgtttggg ccgtaccagc gccaggtctg ttccatgatt tttcctcttt
    37621 cacatagtgg gttccacagc aaagagacgc ggaaccctgg agttgtttag gtatccggat
    37681 gaacaaccag accgcagccg tggcgttgca tcggatgaga tggcgtataa gttctacctt
    37741 ttggtaagac atgtcaaccc gaattctgaa attggttaac cacatcacaa gaatttcact
    37801 ctcatggttg ttgctgcaaa ttgcagcaaa gggtaatcga tggttattga tcagaggatg
    37861 tgacattcat cgcaacaatg gttgaccaat ttacataaca tgtcgcccaa aataacaacg
    37921 gttcaaccag gtaaggtaaa acgttatgca tgtgcttaac attctttggg taatattcgg
    37981 cattggcctg atgctggtac tgaatttgaa gttcaaaatc aattcaatgg tggctttgtt
    38041 ggtggcggcg ctgtccgtcg ggatgctggc gggcatggat ttgatgtcgc tgctgcacac
    38101 catgaaagcg ggcttcggca acacgctggg ggaactggct atcatcgtgg tgttcggtgc
    38161 ggtcatcggt aaattgatgg tcgactccgg cgcggctcac cagatagcac atacgctgct
    38221 ggcgcgtctc ggtctgcgct atgtacagct gtcggtgatt atcatcggcc tgattttcgg
    38281 tctggcgatg ttttatgaag tggcctttat catgttagcg ccgctggtta ttgttattgc
    38341 cgccgaagct aaaattccgt tcctgaaact ggcgatcccg gcagtagcag ctgccactac
    38401 cgcacattca ttgttcccac cgcagccggg tccggtggcg ctagtgaacg cttatggcgc
    38461 ggatatgggg atggtttata tctatggcgt actggtgacg atcccaagtg taatctgcgc
    38521 aggtctgatc ctgccgaagt tcctcggcaa tcttgagcgc ccaacgccat cattcctgaa
    38581 agcagatcaa ccggtagata tgaataatct gccctctttc ggcgtttcga ttctggtgcc
    38641 gctgatccca gcgatcatta tgatctccac caccatcacc aatatctggc tggtaaaaga
    38701 tacccctgcg tgggaagtgg ttaattttat tggttcctcg ccgattgcga tgtttattgc
    38761 gatggtggtt gcattcgtac tctttggcac cgcgcgtggt catgacatgc agtgggtgat
    38821 gaacgctttt gaaagcgcgg tgaagagtat tgcaatggtg attctgatca tcggtgcggg
    38881 tggcgtgttg aagcagacca tcatcgacac cggcattggc gacaccatcg gcatgttgat
    38941 gtcccacggc aatatctcgc cctacatcat ggcatggctg atcaccgtac tgattcgtct
    39001 ggcgacgggt cagggtgtgg tttcagcgat gaccgccgcc gggattatca gtgctgcaat
    39061 ccttgatcca gcaactggtc agctggttgg cgtgaatccg gcgctgctgg tactggcgac
    39121 ggctgcgggt tccaacaccc tcacccacat taatgatgcc tcattctggc tgttcaaagg
    39181 ttactttgac ctgtcagtaa aagacacgtt gaaaacctgg ggtctgctgg agctggtcaa
    39241 ctccgtggtt gggctgatta ttgtgttgat tattagcatg gtagcgtaaa aggacaccag
    39301 agccagccaa tggcaggctc agactgatga caaagtctaa aaatgtgccc ggacagtccc
    39361 ctcgcccctc cggggagagg gttagggtga ggggaacaga ccagcaaagt gcgctttgtt
    39421 tatgccagat gcgacgctga cgcgtcttat ctggcctaca aagggctaac gtgcaggttt
    39481 ttagcttcag gtaatattgc gtaccagcat tagcaatgtc ctgtgatttc tttattgata
    39541 aacaaaagtc acgccaataa tcgattgcac attccctgca gtcacctgcc ctccggtacg
    39601 tgcataattt gccgttaatc ccagactcac cgccgaagtc cctactgctc ctaaagatac
    39661 cgtgttattc gctggaataa tcgtaccgtt gcgcgtcaac tgtacgccga cgccctgtgc
    39721 aggtgaaaac gacgcggtat tggtgaaaat cgagttgccc gcatctgcgg ttgtgccgga
    39781 gaggtaatac cccaggtttt ggcttttcgc acaataaacg gtaagaggaa ttggcactga
    39841 accagggtag tccggcagag taacggtgac atcacgagca gaaacatcgc agccgccagt
    39901 aggcaccacc acatcattat tggcgtaaat attccacaca aactggaaat catcgctgtt
    39961 atagttgttg gtctgtcgca aaataagcac ggcaattaat gagccagctt taatcgccac
    40021 cccgcccgca ctgctcacag gcgtcaaata aagcgccacc ggccacggct tatccgttct
    40081 cgaattataa acaacgcgcg gcgtttcgct ggtggtagga aatggatagc tactgccact
    40141 atattttacg gtcccggaaa aattagataa cacaccgcca taagccgagc ctcgttgcag
    40201 tgtgacatag tctgtaatgg tttccggata atcgttatgg caaaagattt gcgtcgaaag
    40261 atccacgacc aggttttgcc ccacattcac ggcgggcgca aggtttacat aaacattggc
    40321 gctgccaccg ccaataggga tagcggtacc attggcggtt ttacaggcga atgaccaggc
    40381 atttaccgac cagcccatca gcagtacagc aaacagggta ataactcgtt tcattacaat
    40441 catctcttcg ggttcagctg taggtatagg tgatgctaat cactgcctga atggttccct
    40501 gagtggctcc gccatttacc gtcaatgctc tgacctgtaa cgggaagtgc gctgattgtg
    40561 aggaatcatc cacctgaact gttttggttg cgccagtatt caatgtgttg ccactgtcat
    40621 cctgtagctc taactggatg ttttgcgcgg tcccctggtt tttataatat ccggtgctgt
    40681 cggctgcccc gctgaagctg gcagtgaccc tcgacgttcc caccggacaa ttagtcaact
    40741 caagcgcaac atcatgccag gccgatgccg ccccggcaga cataagactg aaagaataaa
    40801 gatcgccgag atcaaccgtg gcattggtgg tggaaactgt gcacggtttg gcgacgacct
    40861 taccgtttac cgtgatggtg acatcggctg cctgtatcgt cgcacttgcg agcgccaata
    40921 ttgccgccaa taaataccca cgtttgcgcc atttcatgag catctccagt tactgatatt
    40981 caagagtgaa ggtagccgtg gcattgatat gccccgcagt gacaggcacc tgtgtcgcca
    41041 ttagccgggc gtaaaaattc aacgtatttg gtttacccgg cgtcagggtc gtccacgaaa
    41101 tcgcggacga tggagcatta aggggtattt gattttgctg ctcattcaga agctgtattc
    41161 ccagtcccga agccgctgac accgtatttt caagtgcaag cagattggca ttgtggctat
    41221 ctgcaacgcc ggtaaaccca acttttacgg cagaaacggc attaccacag ggtgacagca
    41281 aaatacgaaa tggaacaaca ggagtcgtcg cgccaatgtt gttaaattgc ttcgccgcgt
    41341 tttccatcag atcaacagta aaattggttg attcagcggc cacactacag ccgttatctc
    41401 tgacatagcc gcggatagta atcgtgctat ccgcagccaa agcgtgactc accgccagcc
    41461 acaaaaaagc gcacagaaga taaaaaggtt tgtttctcat cacgccccct taacgacatt
    41521 cagctgatag ctgggttaat aactgctgct gactctctgg tggcagttga taattggcga
    41581 cacagtgagc attttcctct tctccccatt tcacctgaac ttttcccgct aaaggcattc
    41641 cgctgaggta aacctgacca ttatccgcaa caatgccgct actctggcta ctctctgatg
    41701 tcaccatcgc cccaaacggc agcggcttat tattgtgggt tagcgtcatg agcagtttta
    41761 tcccaacgcg cgctttaaac tctgctcgca cgatcgcccc acgagtggga acaacgttag
    41821 cgaccgcgtt atctaaatcg acgttatcag ccagggtatt ggtatccagc gccactctgt
    41881 tttccctata ttcagtggca taaggcagca cggcataacc gcgccagtcg gtacgcaccc
    41941 ccgtctggtt ttcgactttt gcatcttttg cgccaggcgc tttaacaagc accaccgtat
    42001 cgtttaacgg ctgccccagc gttacgccat tggcatgagc caatacccca ccgctgactc
    42061 cgtaatagag ctgcttaata tcatcgctat ggctgtaacc gatattggca ttgccgtaac
    42121 caccgcgata attcagcgtg gcgtagcctg tgcttccgct attaccatcg cctcccccgg
    42181 catagccggt ttgcacgcta tagctgaggt tgttgtcttc cagcaacgta ccgtatacac
    42241 cagccagatt ggtcatccga ccgttgagat cgtgtgacat gctgtagctg gcactggcat
    42301 gtcgccactg agatttactg tcagaacgca gccagtggct gaaaggaata ttgacgttaa
    42361 gcgctaacat ctgatcacgt cctttttgcc aggcgttttt cgtcaggcta tagctgagcg
    42421 tccagttgat atcttcgaat gcagtattta atccagcctg gaattgctca tcgacattac
    42481 tcgttcccca ataagtttga tggctaccac tcaaatacag tgttgatgtg cgcccgagtt
    42541 gctgagtaac ggtgagctgt aatttcccgc gtttgttata agcgaggttg taatagtcgg
    42601 tgaatttcgg cttaacctga ataactccgt cctgtgtttc gatgttgtag ccattcattc
    42661 gactgtatgt tgtatcagcg aaattaaaat atccgctggt cgaataacgg taacccacta
    42721 actgaatatt cgtgcctgac tcattgagcg atttgttata gagaaaacgc accgattgtc
    42781 cgtcatgctg actgtcatcg ggaagtgtgg aattagcctg cgtcatatcc acagacagag
    42841 cgcccagtgc ccccatgttt ttcccgatac cgaaattaaa agcacgataa cgatccgcca
    42901 gttgcgttcc accatatatt gtccagccag ccggaaggcc gtggagtaat gtactctgga
    42961 aaaagcgggg tttttcctgc tgcgcatttc cactacggta ttctcctgcc gtaatggaat
    43021 aacgagtatg cccttcacgt tgcaaaagcg ggactgacga atagggtacg gtaaaaatct
    43081 gcgtgctgcc gtcagcctct ttgatcgtta cctgcaagtc accactatta cctgcggcat
    43141 agatatcgtt gatggtaaaa ggccccggtg gcaccgtact attataaatg tcatacccat
    43201 tttgtttaat agtgacctgt gcagtaccac gagcaatacc gtggatcacc ggggcaaatc
    43261 ctctttggct atcgggtaac atattgtcat ctgaggccaa ttgtgcgccg cgaaagttaa
    43321 taccatcgaa aatatcgccc tgagtataac catcacccag cgtcagccgg gaacgtaacg
    43381 gtattatgtc tcgctcaagc caggtattga tatgctgcca tttatttttg ctacctgatg
    43441 atctgtcgct actgttataa ctccaggtgg tattgtcgcg taaacgccac gcaccaatat
    43501 ttaacccact ctgtaggttt aaatatgcat aatggctgtt acccccaatc cgattctgta
    43561 cactatttcc gctgaaatta taattgagca atccggcatt aataccggga tcccataact
    43621 caggaggaat ataaccacgc gcgcgattac tcataaatgc ctgagggatc gtcaggttca
    43681 gtcgctgctg accaacatcc agatgcgcag tagcgtcctg gatcattgtg gttaatggca
    43741 cgcaggcatc atccgccagc agattcatac cggagacaga agccgtattc agccccatac
    43801 tggcaagttg cgcgcgtgtc aggcagggaa caatcccttg ttcactgtcg cccgtattaa
    43861 atgtgacatc acgcgttgcc atataaccat tattcaaata gatatcgaca cgatacgtcc
    43921 ctggcggtaa ttcttgccca ttttcaaaac gcgataaatc ggccacagcc tggggatcat
    43981 ccgctaaaaa acgcgggtta aaatagagtt cggcagatga caaaggtgcc tgtgcggcaa
    44041 aagcacaggc aacaaagagc cggacaaaaa aaccagccaa acgatgctta cgaatatgca
    44101 agcattgtgt gtttcgctgg taaagtctta aattcagata tgacattatt cctccggttt
    44161 aaagtcaccc ggcagtcaat tctttttatt caggcgaaaa attccccctg cgttattcca
    44221 ttacgcccgt cattttgggg gtaagtgcac cataatcatt tattgttcgg taagtaatat
    44281 tgcttcccgc atcagaaggc aatttaaccg tgctttcgcc cattggaggc accaaggcat
    44341 tttcaagaac ccgggttccg gcattcaact ctgttaccgt caggtaatag ggtgtcgggt
    44401 taatcagcgt cagagaattc gcgctacgac gaaatcttaa tttttctgcg gcctgatcgg
    44461 gtggcaacgc taatttagcc gggcgatagt acagtttaat gcggctgata attgcgagct
    44521 gtagcgtatt ctcagtcaat tttgatttat ccattgacgg aatcgcttta acattcatcc
    44581 agaataaact ttcccgatcc tgtggcaatt ggttatttgt tgcatcaaga atacgcaagg
    44641 tattctcttt ttttcccttc atcgcaaaca gaggaggcgt cacgataaaa cgaccatcct
    44701 ttacaccatc ggcattttcc acccatgatt gaattaaata ggtactattt tcatcattat
    44761 ttgtcacggc aagttgcact tgtttttgcc cggccggata aattacgcga gtcgcaccta
    44821 aggccactcc cgcttcagcg cgtccggcaa ccatcattgc cataaacatc aggatacctg
    44881 ccagcaagca gaatgttatt tcctgcgatt tccttacatt gacgttttta ttactcactg
    44941 tcctgttcct gttatcacat tatctgctga acaattactg ataggctaaa gagaaccagg
    45001 cctgggcatt ggcgatgccg ccagtaaccc gacgcccggt agcacgatat ttggcgatga
    45061 aatgtagcga agtagagcct gagtaaagcc gtttccagtt tgctggagga cgattaatcg
    45121 gtacgaggtt tccttcatca tcaaacaacg ctacgccaat attggtggct atccctggcc
    45181 cctctcccac ggaaagcaca tccggatttt taccatccgc gacaccgtga aacgccaccc
    45241 ccacacgttc actcaccacc gtgctacatt cccgtaaatg aataacaaaa ggcaccggtg
    45301 cgctatcttc ccctgccgca tgaaaccggt tactgctgat ttgccccata ttgaccgtca
    45361 tttgtttatc accggcttca atccggcaag tttccgcaat aatgacgccc tgaaattgca
    45421 tatttccgcc aggcagcgtg gtattccatt tatttccggc cagagcaaac attggcagca
    45481 acgacgctaa cagaaataat cttttccttt tcatcgttat ttttatcgca caagggtggg
    45541 catccctgcc cgtaatgacg tccttgaacc tgggtaggtt attgatactg aaccttgaag
    45601 gttgcatccg cattagctgc acccggggtt gcctcgccga ttgcataata acgcgcctgg
    45661 aacggaatgg tgttggtacc gttattcagg gttgtttgtg cactaaatgt cgcaccgtcc
    45721 agcgtcagag cattgcctgt tctgtccagg atctgcacgc caacgtttgt tgcactacct
    45781 gcagcagaac tctgcagagc cagtacatca gtacgcgtag catcaattgc cgtacctaag
    45841 aaggcaacag cggcttttgt ggcaacagtg gtatcgcaat cattcagctg aatgttaaaa
    45901 ccaacggcag agctggttgc tccagcctgc ttcaggctag cggtacgaac ctgtcccaac
    45961 tgaacggttt gatcaacaga gcctgcatca actgcgcaag cggcgttaac aacttcccct
    46021 ttaaagtgaa cggtcccacc atttaccgtc gtagtatcgg ccagagccgc tgcggaactg
    46081 agggacagag ccgacagaac aacgattgcc agagttttaa ttttcatgct gctttccttt
    46141 aaaaaaacta tttctaaatc gacatgggca gtcgttctgt acactttgtt ttgtcaacga
    46201 gtttgactgc caacactgca cagttttccc ccaaaagatg aaacatttgg ggccattttg
    46261 actcatagag gaaagcatcg cgcacaaact ttttcagttt atttgttggc ttaatattct
    46321 attgttatct ttatttatag atttttatat tgcatgaggt ggtttttgga gagaagaatg
    46381 aggaagatgc gtcgagccac agaaacgtta gctttacata tagcggaggt gatgtgaa
//
LOCUS       DAZUDJ010000036        45782 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.036, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000036 DAZUDJ010000000
VERSION     DAZUDJ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 45782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45782
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.036"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            194..820
                     /gene="ydhY"
                     /locus_tag="ACHY1N_002680"
     CDS             194..820
                     /gene="ydhY"
                     /locus_tag="ACHY1N_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein"
                     /protein_id="HFS4044974.1"
                     /translation="MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQE
                     DIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFG
                     DNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCS
                     ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV"
     gene            841..2943
                     /gene="ydhV"
                     /locus_tag="ACHY1N_002681"
     CDS             841..2943
                     /gene="ydhV"
                     /locus_tag="ACHY1N_002681"
                     /EC_number="1.2.7.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase"
                     /protein_id="HFS4044975.1"
                     /translation="MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDE
                     VPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQ
                     MKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCV
                     AAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKR
                     LNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPP
                     GNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGN
                     TCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYS
                     KGVFKRVLPAEEYAEIHWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWN
                     LGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPL
                     KLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTV
                     SPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRN
                     EHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTHETLQR
                     LGLEDIAADLAAHNLLPA"
     gene            2956..3594
                     /gene="ydhW"
                     /locus_tag="ACHY1N_002682"
     CDS             2956..3594
                     /gene="ydhW"
                     /locus_tag="ACHY1N_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310406.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhW family putative oxidoreductase system
                     protein"
                     /protein_id="HFS4044976.1"
                     /translation="MNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAE
                     FIRQHSVAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYS
                     TQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEA
                     AIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP"
     gene            3658..4326
                     /gene="ydhX"
                     /locus_tag="ACHY1N_002683"
     CDS             3658..4326
                     /gene="ydhX"
                     /locus_tag="ACHY1N_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416186.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFS4044977.1"
                     /translation="MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDES
                     RCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCID
                     VCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLA
                     KGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIK
                     KENV"
     gene            4323..5108
                     /gene="phsC"
                     /locus_tag="ACHY1N_002684"
     CDS             4323..5108
                     /gene="phsC"
                     /locus_tag="ACHY1N_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HFS4044978.1"
                     /translation="MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVL
                     GLHALLRARGVKKSVTDYGEKIYLYCKAVRLWHWSNALLFVLLLASGLINHFALVGAT
                     AVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGI
                     MQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYW
                     LLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH"
     gene            5112..5924
                     /gene="ydhT"
                     /locus_tag="ACHY1N_002685"
     CDS             5112..5924
                     /gene="ydhT"
                     /locus_tag="ACHY1N_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdhT"
                     /protein_id="HFS4044979.1"
                     /translation="MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYT
                     DWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCED
                     NARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRI
                     ANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTG
                     VVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRTGVRYRLNEQHQFVEC"
     gene            complement(5936..7540)
                     /gene="ydhS"
                     /locus_tag="ACHY1N_002686"
     CDS             complement(5936..7540)
                     /gene="ydhS"
                     /locus_tag="ACHY1N_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-NAD(P)-binding protein"
                     /protein_id="HFS4044980.1"
                     /translation="MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPY
                     SDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILL
                     GEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVI
                     ATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFI
                     EDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKG
                     EEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNL
                     QEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPS
                     ESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKV
                     KDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTA
                     CAEIGEAMARAVVKPASRARRRLSFD"
     gene            complement(7666..7971)
                     /gene="ydhR"
                     /locus_tag="ACHY1N_002687"
     CDS             complement(7666..7971)
                     /gene="ydhR"
                     /locus_tag="ACHY1N_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HFS4044981.1"
                     /translation="MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTES
                     EKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA"
     gene            complement(8079..8155)
                     /locus_tag="ACHY1N_002688"
     tRNA            complement(8079..8155)
                     /locus_tag="ACHY1N_002688"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8119..8121),aa:Val,seq:gac)
     gene            complement(8160..8236)
                     /locus_tag="ACHY1N_002689"
     tRNA            complement(8160..8236)
                     /locus_tag="ACHY1N_002689"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8200..8202),aa:Val,seq:gac)
     gene            8544..9800
                     /gene="ydhQ"
                     /locus_tag="ACHY1N_002690"
     CDS             8544..9800
                     /gene="ydhQ"
                     /locus_tag="ACHY1N_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
                     /protein_id="HFS4044982.1"
                     /translation="MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENT
                     VVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRH
                     PEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGE
                     LLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGT
                     DGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRA
                     PVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDGVTFIVGNINL
                     NGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITD
                     ASRQTLCNALKLQPDEDGIGATLQPA"
     gene            complement(9841..11214)
                     /gene="mdtK"
                     /locus_tag="ACHY1N_002691"
     CDS             complement(9841..11214)
                     /gene="mdtK"
                     /locus_tag="ACHY1N_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HFS4044983.1"
                     /translation="MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLI
                     MLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSM
                     RDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTV
                     SLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITF
                     TAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVI
                     ILQRASR"
     gene            11429..12070
                     /gene="ribE"
                     /locus_tag="ACHY1N_002692"
     CDS             11429..12070
                     /gene="ribE"
                     /locus_tag="ACHY1N_002692"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HFS4044984.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAH
                     NGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGH
                     IMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA"
     gene            complement(12110..13258)
                     /gene="cfa"
                     /locus_tag="ACHY1N_002693"
     CDS             complement(12110..13258)
                     /gene="cfa"
                     /locus_tag="ACHY1N_002693"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HFS4044985.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIASAR
                     LFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
                     EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTIL
                     LQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLN
                     VDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPE
                     IADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR"
     gene            complement(13549..14760)
                     /gene="punC"
                     /locus_tag="ACHY1N_002694"
     CDS             complement(13549..14760)
                     /gene="punC"
                     /locus_tag="ACHY1N_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1990961 - xenobiotic detoxification by
                     transmembrane export across the plasma membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside transporter PunC"
                     /protein_id="HFS4044986.1"
                     /translation="MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVS
                     ASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRF
                     VQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQ
                     AIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLV
                     LFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAA
                     LQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNH
                     GNAEVAHSESH"
     gene            14873..15805
                     /gene="punR"
                     /locus_tag="ACHY1N_002695"
     CDS             14873..15805
                     /gene="punR"
                     /locus_tag="ACHY1N_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator PunR"
                     /protein_id="HFS4044987.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
                     RDMGMLSWSCVVASHHPLALMNGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     VVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQND
                     MSPALTWLLEYLGDSETLNKEWLREPEETPATGD"
     gene            complement(15802..16827)
                     /gene="purR"
                     /locus_tag="ACHY1N_002696"
     CDS             complement(15802..16827)
                     /gene="purR"
                     /locus_tag="ACHY1N_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HFS4044988.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVID
                     NAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQ
                     GDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDN
                     VRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADG
                     PFRDYRR"
     gene            17126..17215
                     /gene="cydH"
                     /locus_tag="ACHY1N_002697"
                     /gene_synonym="ynhF"
     CDS             17126..17215
                     /gene="cydH"
                     /locus_tag="ACHY1N_002697"
                     /gene_synonym="ynhF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I accessory subunit CydH"
                     /protein_id="HFS4044989.1"
                     /translation="MSTDLKFSLVTTIIVLGLIVAVGLTAALH"
     gene            17381..18550
                     /gene="ydhP"
                     /locus_tag="ACHY1N_002698"
     CDS             17381..18550
                     /gene="ydhP"
                     /locus_tag="ACHY1N_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4044990.1"
                     /translation="MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGM
                     LISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRIL
                     TSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
                     SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMF
                     TLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLL
                     MVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAF
                     NLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS"
     gene            complement(18696..19277)
                     /gene="sodB"
                     /locus_tag="ACHY1N_002699"
     CDS             complement(18696..19277)
                     /gene="sodB"
                     /locus_tag="ACHY1N_002699"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HFS4044991.1"
                     /translation="MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFG
                     SFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA"
     gene            complement(19405..20220)
                     /gene="mepH"
                     /locus_tag="ACHY1N_002700"
     CDS             complement(19405..20220)
                     /gene="mepH"
                     /locus_tag="ACHY1N_002700"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-endopeptidase MepH"
                     /protein_id="HFS4044992.1"
                     /translation="MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKA
                     DKKKSTATTKKTQKTAKKAASKSTTTSKTASSVKKSSITASKNAKTRSKHAVNKTASA
                     SFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGG
                     SSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQG
                     RGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR"
     gene            20555..20902
                     /gene="grxD"
                     /locus_tag="ACHY1N_002701"
     CDS             20555..20902
                     /gene="grxD"
                     /locus_tag="ACHY1N_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HFS4044993.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALAACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIVIEMYQRGELQQLIKE
                     TAAKYKSEEPDAE"
     gene            complement(20953..25569)
                     /gene="lhr"
                     /locus_tag="ACHY1N_002702"
     CDS             complement(20953..25569)
                     /gene="lhr"
                     /locus_tag="ACHY1N_002702"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFS4044994.1"
                     /translation="MADNPDSSSLLPDVFSPATRDWFLRAFKQPTAVQSQTWHVAARS
                     EHALVIAPTGSGKTLAAFLYALDRLFREGGEDTCEAHKRKTSRILYISPIKALGTDVQ
                     RNLQLPLKGIADERRRRGETEVNLRVGIRTGDTPAQERSKLTRNPPDILITTPESLYL
                     MLTSRARETLRGVETVIIDEVHAVAGSKRGAHLALSLERLDALLHTSAQRIGLSATVR
                     SASDVAAFLGGDRPVTVVNPPAMRHPQIRIVVPVANMDDVSSVASSTGEDSHAGREGS
                     IWPYIETGILDEVLRHRSTIVFTNSRGLAEKLTARLNELYAARLQRSPSIAVDAAHFE
                     STSGATSNRVQSSDVFIARSHHGSVSKEQRAITEQALKSGELRCVVATSSLELGIDMG
                     AVDLVIQVATPLSVASGLQRIGRAGHQVGGVSKGLFFPRTRRDLVDSAVIVECMFAGR
                     LENLTPPHNPLDVLAQQTVAAAAMEALQVDEWYSRVRRAAPWKDLPRRVFDATLDMLS
                     GRYPSGDFSAFRPKLVWNRETGILTARPGAQLLAVTSGGTIPDRGMYSVLLPEGEEQA
                     GSRRVGELDEEMVYESRVNDIITLGATSWRIQQITRDQVIVTPAPGRSARLPFWRGEG
                     NGRPAELGEMIGDFLHLLADGAFFSGTIPPWLAEENTIANIQGLIDEQRNATGIVPGS
                     RHLVLERCRDEIGDWRIILHSPYGRRVHEPWALAIAGRIHALWGADASVVASDDGIVA
                     RIPDTDGKLPDAAIFLFEPEKLLQIVREAVGSSALFAARFRECAARALLMPGRTPGHR
                     TPLWQQRLRASQLLEIAQGYPDFPVILETLRECLQDVYDLPALERLMRRLNGGEIQIS
                     DVTTTTPSPFATSLLFGYVAEFMYQSDAPLAERRASVLSLDSELLRNLLGQVDPGELL
                     DPQVIRQVEEELQRLAPGRRAKGEEGLFDLLRELGPMTVEDLAQRHTGSSEEVASYLE
                     NLLAVKRIFPAMISGQERLACMDDAARLRDALGVRLPESLPEIYLHRVSYPLRDLFLR
                     YLRAHALVTAEQLAHEFSLGIAIVEEQLQQLREQGLVMNLQQDIWVSDEVFRRLRLRS
                     LQAAREATRPVAATTYARLLLERQGVLPATDGSPALFASTSPGVYEGVDGVMRVIEQL
                     AGVGLPASLWESQILPARVRDYSSEMLDELLATGAVIWSGQKKLGEDDGLVALHLQEY
                     AAESFTPAEADQANRSALQQAIVAVLADGGAWFAQQISQRIRDKIGESVDLSALQEAL
                     WALVWQGVITSDIWAPLRALTRSSSNARTSTRRSHQARRGRPVYAQPVSPLVSYNTPN
                     LAGRWSLLQVEPLNDTERMLALAENMLDRYGIISRQAVIAENIPGGFPSMQTLCRSME
                     DSGRIMRGRFVEGLGGAQFAERLTIDRLRDLATQATQTRHYTPVALSANDPANVWGNL
                     LPWPAHPATLVPTRRAGALVVVSGGKLLLYLAQGGKKMLVWQEKEELLAPEVFHALTT
                     ALRREPRLRFTLTEVNDLPVRQTPMFTLLREAGFSSSPQGLDWG"
     gene            complement(25662..26309)
                     /gene="rnt"
                     /locus_tag="ACHY1N_002703"
     CDS             complement(25662..26309)
                     /gene="rnt"
                     /locus_tag="ACHY1N_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016896 - RNA exonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HFS4044995.1"
                     /translation="MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKV
                     VRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALG
                     QTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPAAEEV"
     gene            complement(26412..26819)
                     /gene="gloA"
                     /locus_tag="ACHY1N_002704"
     CDS             complement(26412..26819)
                     /gene="gloA"
                     /locus_tag="ACHY1N_002704"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFS4044996.1"
                     /translation="MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGP
                     VKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN"
     gene            complement(26900..27997)
                     /gene="nemA"
                     /locus_tag="ACHY1N_002705"
     CDS             complement(26900..27997)
                     /gene="nemA"
                     /locus_tag="ACHY1N_002705"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-ethylmaleimide reductase"
                     /protein_id="HFS4044997.1"
                     /translation="MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPGI
                     VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEV
                     VDAGIEEWGADRIGIRISPIGTFQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDW
                     AGGEPYTDAFREKVRARFHGPIIGAGAYTVEKAETLIGKGLIDAVAFGRDWIANPDLV
                     ARLQRKAELNPQRAESFYGGGAEGYTDYPTL"
     gene            complement(28034..28633)
                     /gene="nemR"
                     /locus_tag="ACHY1N_002706"
     CDS             complement(28034..28633)
                     /gene="nemR"
                     /locus_tag="ACHY1N_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416166.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NemR"
                     /protein_id="HFS4044998.1"
                     /translation="MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGS
                     FYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGT
                     ISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQA
                     QVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV"
     gene            28736..28975
                     /gene="ydhL"
                     /locus_tag="ACHY1N_002707"
     CDS             28736..28975
                     /gene="ydhL"
                     /locus_tag="ACHY1N_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HFS4044999.1"
                     /translation="MAEQLEFFPVQSPCRGICQSDERGFCRGCFRSRDERFNWNKMSD
                     GEKQEVLRLCRQRLMRKLRANKPASSDEPEQPSLF"
     gene            29024..29920
                     /gene="ydhF"
                     /locus_tag="ACHY1N_002708"
     CDS             29024..29920
                     /gene="ydhF"
                     /locus_tag="ACHY1N_002708"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFS4045000.1"
                     /translation="MVQRITIAPQGPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTAREENVIGHYITD
                     RDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVADAFKHLHQSGKVRHFGVSNF
                     TPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLF
                     NDDYFQPLRDELAVVAEELNAGSIEQVVYAWVLRLPSQPLPIIGSGKIERVRAAVEAE
                     TLKMTRQQWFRIRKAALGYDVP"
     gene            30001..30522
                     /gene="sodC"
                     /locus_tag="ACHY1N_002709"
     CDS             30001..30522
                     /gene="sodC"
                     /locus_tag="ACHY1N_002709"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC"
                     /protein_id="HFS4045001.1"
                     /translation="MKRFSLAILALVVATGAQAASEKVEMNLVTSQGVGQSIGSVTIT
                     ETDKGLEFSPDLKALPPGEHGFHIHAKGSCQPATKDGKASAAESAGGHLDPQNTGKHE
                     GPEGAGHLGDLPALVVNNDGKATDAVIAPRLKSLDEIKDKALMVHVGGDNMSDQPKPL
                     GGGGERYACGVIK"
     gene            complement(30523..32535)
                     /gene="ydhK"
                     /locus_tag="ACHY1N_002710"
     CDS             complement(30523..32535)
                     /gene="ydhK"
                     /locus_tag="ACHY1N_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFS4045002.1"
                     /translation="MNASSWSLRNLPWFKATLAQWRYALRNTIAMCLALTVAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPWFFLLSMSA
                     WLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGI
                     LCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWQPETNDAIRAAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPGATREIL
                     EQLLTALASSQTDAYTVARIIAPLRPTNVADYRHVAFWQRLRYFCRLYLQSSQELHRL
                     QSGVDDHARLARTSALARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDVGANALTLA
                     AISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLAT
                     MQLLKSQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFA
                     ILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQDALARR
                     WLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATL
                     EELQRICNSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS"
     gene            complement(32535..33392)
                     /gene="ydhJ"
                     /locus_tag="ACHY1N_002711"
     CDS             complement(32535..33392)
                     /gene="ydhJ"
                     /locus_tag="ACHY1N_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310380.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HFS4045003.1"
                     /translation="MSIKTIKYFSTIIVAIVAVLAGWWLWNYYMQSPWTRDGKIRAEK
                     VSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKAN
                     NEANRRRHLSQNFISAEELDTANLNVKAMQASVNAAQATLKQTQWQLAQTEIRAPVSG
                     WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKT
                     LRGHVSSIGRAIYDQSVESDSSLIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSG
                     TTCSIAVGQ"
     gene            complement(33395..33631)
                     /gene="ydhI"
                     /locus_tag="ACHY1N_002712"
     CDS             complement(33395..33631)
                     /gene="ydhI"
                     /locus_tag="ACHY1N_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HFS4045004.1"
                     /translation="MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVVHRLL
                     RGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW"
     gene            33832..34266
                     /gene="slyA"
                     /locus_tag="ACHY1N_002713"
     CDS             33832..34266
                     /gene="slyA"
                     /locus_tag="ACHY1N_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HFS4045005.1"
                     /translation="MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLP
                     PDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISE
                     MEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG"
     gene            complement(34313..34780)
                     /gene="slyB"
                     /locus_tag="ACHY1N_002714"
     CDS             complement(34313..34780)
                     /gene="slyB"
                     /locus_tag="ACHY1N_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HFS4045006.1"
                     /translation="MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGT
                     IVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTVGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSPGQRVVLASNGSQVTVSPR"
     gene            35054..36163
                     /gene="anmK"
                     /locus_tag="ACHY1N_002715"
     CDS             35054..36163
                     /gene="anmK"
                     /locus_tag="ACHY1N_002715"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HFS4045007.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSL
                     KQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVW
                     HEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHST
                     ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGK
                     VILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAV
                     TISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP"
     gene            36261..36590
                     /gene="mliC"
                     /locus_tag="ACHY1N_002716"
     CDS             36261..36590
                     /gene="mliC"
                     /locus_tag="ACHY1N_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416156.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
                     /protein_id="HFS4045008.1"
                     /translation="MSMKKLLLICLPVLLTGCSAFNQLVEHMQTATLEYQCDEKPLTV
                     KLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGDEATVYKRDRIVLNNC
                     QLQNPQR"
     gene            36649..37305
                     /gene="pdxH"
                     /locus_tag="ACHY1N_002717"
     CDS             36649..37305
                     /gene="pdxH"
                     /locus_tag="ACHY1N_002717"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HFS4045009.1"
                     /translation="MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACE
                     AKLADPTAMVVATVDEHAQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQLENNPRVSLL
                     FPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
                     "
     gene            37434..38708
                     /gene="tyrS"
                     /locus_tag="ACHY1N_002718"
     CDS             37434..38708
                     /gene="tyrS"
                     /locus_tag="ACHY1N_002718"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFS4045010.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVD
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQS
                     DPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK"
     gene            38767..39630
                     /gene="pdxY"
                     /locus_tag="ACHY1N_002719"
     CDS             38767..39630
                     /gene="pdxY"
                     /locus_tag="ACHY1N_002719"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase"
                     /protein_id="HFS4045011.1"
                     /translation="MMKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNH
                     TQYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKA
                     ANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNN
                     VEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQ
                     PVGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIA
                     KPEHYFSATKL"
     gene            complement(39674..40279)
                     /gene="gstA"
                     /locus_tag="ACHY1N_002720"
     CDS             complement(39674..40279)
                     /gene="gstA"
                     /locus_tag="ACHY1N_002720"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HFS4045012.1"
                     /translation="MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYF
                     VVNPKGQVPAVLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIA
                     TELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFT
                     VLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK"
     gene            complement(40385..41887)
                     /gene="dtpA"
                     /locus_tag="ACHY1N_002721"
     CDS             complement(40385..41887)
                     /gene="dtpA"
                     /locus_tag="ACHY1N_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:1904680 - peptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HFS4045013.1"
                     /translation="MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVN
                     IGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINY
                     RNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMI
                     VAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGLAVEPEQYQALNPFWIIIGSP
                     ILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDP
                     LMSLEVYGRVFLQIGVATAIIAVLMLLTAPKLHRMTQDDAADKAAKAAVA"
     gene            complement(42498..43133)
                     /gene="nth"
                     /locus_tag="ACHY1N_002722"
     CDS             complement(42498..43133)
                     /gene="nth"
                     /locus_tag="ACHY1N_002722"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFS4045014.1"
                     /translation="MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATD
                     VSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI"
     gene            complement(43133..43828)
                     /gene="rsxE"
                     /locus_tag="ACHY1N_002723"
     CDS             complement(43133..43828)
                     /gene="rsxE"
                     /locus_tag="ACHY1N_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxE"
                     /protein_id="HFS4045015.1"
                     /translation="MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDG
                     ADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRTEAA
                     AERALPNGETGNV"
     gene            complement(43832..44452)
                     /gene="rsxG"
                     /locus_tag="ACHY1N_002724"
     CDS             complement(43832..44452)
                     /gene="rsxG"
                     /locus_tag="ACHY1N_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HFS4045016.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKA
                     LFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLEATAPDGYSG
                     AIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAV
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE"
     gene            complement(44456..45514)
                     /gene="rsxD"
                     /locus_tag="ACHY1N_002725"
     CDS             complement(44456..45514)
                     /gene="rsxD"
                     /locus_tag="ACHY1N_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HFS4045017.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTL
                     VQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGT
                     VFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQ
                     VIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGILAGA
                     GWQWVNLAWLAGGLWLLWQKAIRWHIPLSFLVTLALCATLGWLFSPETLAAPQIHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(45515..>45782)
                     /locus_tag="ACHY1N_002726"
     CDS             complement(45515..>45782)
                     /locus_tag="ACHY1N_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001439589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045018.1"
                     /translation="AAVEAAIARAKARKLEQQQANAEPEEQVDPRKAAVEAAIARAKA
                     RKLEQQQTNAEPEEQVDPRKAAVAAAIARAQAKKAAQQKVVNED"
BASE COUNT        11520 a        11333 c        11947 g        10982 t
ORIGIN      
        1 gctcagaata atcacattat tttttctcct aaccataaag gattagttta tcggcgttaa
       61 atcttttctc atacactatc gggttaggga aaatatctgg tgttggggac agagtcagca
      121 gcgtattagt tgaatgctta atatcaggct gctgaattgt cagcactgtg tttgcgaaga
      181 ggatgcgaaa taaatgaacc cggttgatcg tccactatta gatattggct taacgcgatt
      241 agaattcttg cgtatatcag gaaaaggcct tgctggtcta acaattgccc ctgcgttact
      301 gtcacttttg ggttgcaaac aggaagatat tgatagcggc acagtagggt tgataaatac
      361 acccaaaggg gtgctggtga cccagcgagc gcgatgcacg ggttgccacc gctgtgaaat
      421 ctcttgtacc aacttcaacg atggctcagt agggacattc ttctcccgta tcaaaatcca
      481 ccgcaattat ttctttggcg acaacggggt tggctctggc ggcggcctgt atggcgatct
      541 caactatacc gcggacacct gccgtcaatg caaagagccg caatgcatga acgtctgccc
      601 gattggtgcg attacctggc agcagaaaga aggctgtatt accgtcgatc ataaacgctg
      661 tattggctgt agcgcctgta ctacggcatg cccgtggatg atggccaccg taaataccga
      721 aagtaaaaaa tcctcgaaat gtgtgttatg cggtgaatgc gcaaacgcct gcccaacagg
      781 ggcgttaaaa attatcgagt ggaaagatat tactgtgtga atcttgcaaa ggaaaaaatc
      841 atggctaacg gttggacagg taatatatta agagtcaatc tcacgacagg aaatattacc
      901 ctcgaagatt ccagtaagtt taaaagtttt gtcggtggca tgggcttcgg ctacaaaatt
      961 atgtatgacg aagtaccgcc aggcacgaaa cctttcgatg aagcgaataa attagtcttt
     1021 gctaccggcc cattaactgg atctggtgcc ccctgtagtt ctcgcgtaaa tatcacctca
     1081 ctttctactt ttaccaaagg aaatttagtt gtcgatgccc atatgggtgg cttttttgca
     1141 gcgcaaatga aattcgctgg atacgacgtc attattatcg aagggaaggc gaaatcaccg
     1201 gtatggctga agattaaaga tgacaaagtt agcctggaaa aagccgattt cttatgggga
     1261 aaagggacgc gcgcaacgac ggaagaaatt tgtcgattga ccagtccgga aacctgtgtg
     1321 gcggctattg gtcaggctgg ggaaaacctt gttcctctct ctggcatgtt gaatagccgt
     1381 aaccacagcg gcggtgcggg aactggcgca attatgggtt cgaaaaacct gaaagcgatt
     1441 gcggttgaag ggacgaaagg ggtcaacatt gccgatcgtc aggagatgaa gcgtctcaac
     1501 gattacatga tgactgaact tattggtgcg aataacaacc atgtcgtgcc aagtacgccg
     1561 caatcgtggg cagagtattc agatcccaag tcacgttgga cagcacgtaa agggctgttt
     1621 tggggcgcgg ctgaaggtgg tccgattgaa acgggggaaa ttccgccagg caatcagaac
     1681 acggtcggct ttcgtaccta taaatccgtt tttgacttag gtccggcggc agagaaatac
     1741 acagtaaaaa tgagtggctg ccactcttgc ccgatccgtt gtatgaccca aatgaatatt
     1801 cctcgggtga aagagtttgg cgtgcccagc acaggtggta acacttgtgt agccaacttt
     1861 gtccatacca ccatcttccc gaacgggccg aaagattttg aagataaaga cgatggtcgt
     1921 gtgattggta acctggttgg tctgaatttg ttcgatgact acggcctatg gtgtaactac
     1981 gggcagctgc atcgcgactt tacttattgt tacagcaaag gggtgttcaa gcgtgttctg
     2041 ccagctgaag agtatgcgga aattcactgg gatcaactgg aagcgggtga cgttaatttc
     2101 attaaagatt tttactaccg tctggcgcat cgtgtgggtg agctgagtca cctggctgat
     2161 ggttcatatg ccatcgcaga acgctggaat ttgggtgaag agtactgggg ctacgcaaaa
     2221 aataaactct ggtcgccgtt tggctatccg gttcaccatg ccaatgaagc gtcagcgcag
     2281 gtcggttcca ttgttaactg tatgttcaac cgtgactgca tgacgcatac ccatatcaat
     2341 tttattggtt cgggtttgcc attgaaactg cagcgtgaag tggcgaaaga gctttttggt
     2401 tctgaagatg cctacgatga aaccaaaaac tacacgccaa tcaatgacgc aaaaattaaa
     2461 tatgcaaagt ggtcgctgtt gcgggtctgt ttgcataacg ccgtcaccct gtgcaactgg
     2521 gtctggccaa tgaccgtttc gccgctgaaa agccgtaatt accggggcga tctggcgctt
     2581 gaagccaaat tcttcaaagc gatcaccggc gaagagatga ctcaggaaaa attagattta
     2641 gctgcagagc gtatctttac gttgcatcgt gcctacacgg taaaactgat gcaaaccaaa
     2701 gatatgcgta atgaacacga tcttatctgt tcctgggtat tcgacaagga tccgcagatc
     2761 ccggtcttta ctgaaggtac tgacaaaatg gatcgtgacg atatgcatgc ttcgctcacg
     2821 atgttctaca aagaaatggg ctgggaccca cagcttggtt gtccgaccca cgaaacattg
     2881 cagcgtctgg ggctggaaga tattgccgcc gatctggcag cacacaatct actgcctgcg
     2941 taaggaatgg gtgagatgaa ccatcgggat gaattgccgt tagcgaaagt cagcgaagtt
     3001 gacgaggcga agcggcaatg gttacagggg atgcgtcacc ccgttgatac ggtaaccgaa
     3061 ccagaaccgg ctgaaatcct ggcagagttc attcgccagc attctgtggc tgggcagctg
     3121 gtggcgcgcg ccgtgtttct ctcgccaccc tattcggttg cagaagagga actgtcagtt
     3181 ttgctggaaa gcattaagca gaacggagac tacgcggata tcgcttgtat gacgggaagt
     3241 caggatgatt actattactc aacgcaggcc atgagtgaaa actacgcggc gatgtctttg
     3301 caagttgtgg agcaggacat ttgtcgcgcc attgcacacg ccgttcgttt tgagtgccag
     3361 acgtatcctc gtccttacaa agtcgccatg ctgatgcaag cgccatatta cttccaggaa
     3421 gcgcagattg aagccgcgat cgccgcgatg gatgttgcac ctgaatatgc cgatatacgg
     3481 caggtggagt catcgacggc ggtgttgtac ttgtttagcg agcgatttat gacctatggc
     3541 aaggcttatg gcttatgcga atggttcgag gtagagcagt ttcagaaccc ctgaaatttc
     3601 agggagatgt catggatagg gtggacagtt gcagccactg cattagggga taatcagatg
     3661 tccttcactc gacgcaaatt tgttctgggg atgggaacag taatcttttt tactggttct
     3721 gcgtcttctc tgttagcgaa cacgaggcaa gaaaaggaag ttcggtatgc catgattcat
     3781 gacgagtcac ggtgcaatgg ctgtaatatt tgcgcccgcg catgccgtaa aactaaccac
     3841 gtccccgctc agggaagccg tttatcgata gcacacattc cagtcaccga taacgataac
     3901 gaaacgcagt atcacttttt tcgccagtca tgtcagcact gcgaagatgc tccgtgcatc
     3961 gacgtatgcc cgacaggggc gtcgtggcgt gatgagcagg ggatcgtgcg ggtagaaaaa
     4021 tcgcagtgca tcggctgcag ttattgcatt ggcgcttgtc cgtaccaggt tcgctacctt
     4081 aaccctgtca ctaaagtggc agataaatgt gatttctgcg ctgagtcccg actggcaaaa
     4141 ggctttccgc ccatttgcgt cagcgcctgc ccggaacacg cattgatctt tggtcgcgaa
     4201 gatagcccag aaattcaggc gtggttgcag caaaataaat actatcaata tcagctacct
     4261 ggtgccggga aaccgcatct gtatcgccgg ttcggtcaac atttgattaa aaaggaaaat
     4321 gtatgaaccc gtcgcaacat gctgaacagt ttcagagcca gttagcgaac tatgtgccac
     4381 agttcactcc cgaattttgg ccggtgtggt tgatcattgc cggagtattg ctggttggga
     4441 tgtggttggt gctggggctg catgccttgc ttcgtgctcg tggcgtgaag aaatcagtca
     4501 ccgattatgg tgagaagatt tatctttact gcaaagcggt cagattatgg cactggtcga
     4561 atgcgttact ctttgtattg ttgctggcaa gtgggctgat aaatcacttt gcgctggtgg
     4621 gcgcaactgc ggttaaaagt ctggttgcgg tgcatgaagt ttgcggattt ttgttactcg
     4681 catgctggct cggctttgtg ctgatcaatg ccgttggggg taatggtcac cactatcgca
     4741 ttcgtcgtca ggggtggctg gagcgagcgg caaaacaaac gcgattttat ttgtttggca
     4801 ttatgcaggg ggaagaacat cctttcccgg caacaaccca gtctaaattt aatcccttac
     4861 agcaggtcgc ctatgttggt gttatgtatg gattgctgcc gttgttacta ttgacggggc
     4921 tgctgtgtct ctatccgcaa gccgtgggag atgtgtttcc tggcgtaaga tactggttat
     4981 tgcaggcgca ttttgctctg gcatttataa gcctcttttt tatcttcggt catctttatc
     5041 tttgcaccac ggggcgtacg ccacacgaaa cctttaaaag catggtcgat ggctatcacc
     5101 ggcactaacg aatgatcatt acacgagcag acctgcgaga atggcgtatc ggagcggtga
     5161 tgtatcgctg gttcctgcgc catttcccac gcggcggtag ttatgccgat attcatcatg
     5221 cactgattga ggaaggatat acggactggg cggagagtct ggttgagtat gcgtggaaaa
     5281 aatggctggc ggatgaaaac ttcgcgcatc aggaagtttc ctctatgcaa aaactggcca
     5341 cagaccccgg agagatacca ttttgcagtc agtttgcccg cagcgacgat catgctcgca
     5401 tcggctgttg tgaggataac gcccgaatcg caaccgctgg gtatgccgcg caaattgcca
     5461 gtatgggtta tagcgtgcgg attggaagtg tcggctttaa cagtcacatt ggcagctccg
     5521 gtgaacgcgc acgggttgct gtaaccggta attcttcgcg gataagcagc gctggagata
     5581 gtagtcggat tgcgaatacc ggaatgcgag tacgcgtttg tacattgggt gaacggtgtc
     5641 atgtcgccag taatggtgac ctggtgcaaa tcgccagctt tggcgcaaac gccagaattg
     5701 ccaacagcgg cgacaatgta cacatcattg ccagcggtga aaattcaacg gtagtgagca
     5761 cgggcgtggt cgactcaatt attctcgggc cagggggaag cgccgcactg gcatatcatg
     5821 acggcgaaag agttcgcttc gccgtcgcca ttgaaggtga aaacaatatt cgaaccggag
     5881 tccgctatcg tcttaatgaa cagcatcagt ttgttgagtg ctgatagctt tacctttaat
     5941 caaacgaaag acgccgacga gcacgggatg caggctttac gaccgcccga gccatcgcct
     6001 caccaatttc tgcacatgcc gtaagtccct gaacgaaagg ctggtcgtgc atcaaccagg
     6061 gcaacgcgcc gaacgctacg cgtccacgaa tatcttcggg ttgctgtaac gtataatctt
     6121 cgccaacatc agggatttca tcccctgttt tctgtaattg ctcgcgtagc ccagggaaag
     6181 gaatatcttt cactttaagc ggacgctgtc cgcgggcatc aataaaaacg tcaaacgagt
     6241 agctgttgtc ttccgttttc aggacggtgc gcgactcatt aatttccatt ttgtagtctt
     6301 caccgagggc gagaatatga atgattcccg cttcacgtaa ggcaagtagg cgacgaatag
     6361 actctgaagg gattgccgca taattatcga tgaaaaccct ggcaaggcct ttactgaacc
     6421 gtttatggtc gtgttcattc agatgaggaa caatttcctg tacggcttca tgcaggcgca
     6481 gaatgacata acgccaggga acagtatgtt tttctcgttt attgcgttcg acttcctgga
     6541 gatttttttc tgcccagtca aatgggtcgc gttgtttgcg ctcggcaaac caggcttgag
     6601 caaaggaatc gacattcagg ctctctaagg ctatgcgttg gctccagtct ggatcagcaa
     6661 acttgatttc ctctactatc aatctaaata cccgatccaa aaggccctct tcaccttttt
     6721 gaatctcagc atttaatgcc tgatcggtga cgatgtgtaa gggctcgtag ggaatagggc
     6781 aatagaaatc ggcttcgggt aaaatacccg tgcgcgacat caacgtaata tttagctttt
     6841 cacttgcgtt atcgcggtta aaaacgacgt gttgtttatc atcttcaatg aacgaaccat
     6901 gctgaatagc cactgccatt gccgcatcca gtccgctcaa ggatgttccc ataataccca
     6961 cgttacacgc atcgaccttt gcttccatca ggcctgacca cggactggga aaatacgttc
     7021 tggttgcttc ttcttcatca ggccagacgt gacccgtggc aatcaccgct aaatcaaacg
     7081 tctcgctggg taaatcctga tttgtagcga gcatgacgcc agcatttgta atttgcagat
     7141 cggtaacctg gcatgattca taaacagcca ctgcaaattt ttgctgtcgt gcctggtcta
     7201 ctaatcgtaa aaattgatcg cggaaatatt cgcccagcag aattcgcggt aaaaactgac
     7261 gatcgtgcaa ggtttctttt ttaacgccat aacgctggag atggctggct tcttgctttt
     7321 gtagccattc gagatacgta caattaatcg gcggtatttc aatactggca atatttgcca
     7381 gcatcatttt tgagttttcc tcatcactgt atggcatccc gacaccggcc tcgtcagcct
     7441 gctcgaagat agaaatagaa agtggagttt gttgctgtag aagcgagaat aaggtgtaga
     7501 tccccgtagg cccggcaccc acaatagcaa tttttttcat tgttacttac ctgtacgcat
     7561 tctttcgaat ttagtgttat cagataagtt tggttgagat ttttagaatt tgagaaattt
     7621 cagacaggga tgaaaagggc gctaaccgcc cttgattaaa ttctgtcagg cgagttttgc
     7681 ctgattgatt tgactcagtg gctcattgac atcgaaaact ttggcgacaa cttcctcaac
     7741 gccgagattt ttaagtcggg cagtatgttt ttccagatag gcaagggcgc ttttttcatc
     7801 agtaaaaaga tagatcccac cggcttcgtg gttcttttca ctttctgtcc ataccttcca
     7861 cagaaaacca ggttcctgat taatcgactc agcaagcggt ttaagctgct cagccattgc
     7921 gtcgccaaat gggccattaa aagcaaaatg aagttgtaac aaagttgcca tagcgattct
     7981 ccttctgata acgcatacga agacagtgta aatcttttaa cgtattggat acagagaaga
     8041 aacagaggga aaaaggagaa gaccagatta agaaaatctg gtgcgtccga gtggactcga
     8101 accaccgacc cccaccatgt caaggtggtg ctctaaccaa ctgagctacg gacgcaggat
     8161 ggtgcgttca attggactcg aaccaacgac ccccaccatg tcaaggtggt gctctaacca
     8221 actgagctat gaacgcaacg ttgtaggtga caacggggac gaatattagc ggcagagtgg
     8281 gaaggtggca agaggcaaaa cgtaattttc tgcgctattt cgaccgtttg cagagctttt
     8341 aagcaaattg gctatatttt gttgatttgc aagggcgatt tttattcagg atcgcattta
     8401 catctgatac aacccaataa ttcgtgtatc agagtttaaa cagagttgtt tgccaccatc
     8461 tcaaatctgt cgtggataaa tcctccgtag cctttacact taggtagcaa taaaggcaca
     8521 cagatgcagc aaaggaataa atcatgggat ctgatgcgaa aaacttgatg agcgacggga
     8581 atgtgcaaat tgttaagacc ggcgaggtca ttggcgcgac gcaacttact gaaggcgagt
     8641 tgattgttga agctggcgga agagccgaaa ataccgtggt cacgggggct ggctggttga
     8701 aagtggcaac cggtgggatc gccaaatgca cacagtacgg taacaatggc acgctatcgg
     8761 tcagcgacgg tgccattgcc acagatattg ttcagtccga gggaggcgca attagtctct
     8821 ctacgctcgc tacggttaat ggccgccatc ccgaaggtga attcagcgtt gatcagggtt
     8881 atgcctgcgg tttgttgctg gaaaatggcg gtaacctgcg tgtactggaa ggacatcgcg
     8941 cggaaaaaat cattctcgat caagagggcg gcctgttggt taatgggaca acctcagcgg
     9001 tcgtggtaga tgaaggtggt gaattgttgg tgtatccagg tggggaagcc agcaattgtg
     9061 agattaatca gggcggcgtt tttatgctgg ccgggaaagc cagtgatacg ttgcttgctg
     9121 gtggcaccat gaataatctc ggtggtgaag actctgacac tattgttgag aatggatcca
     9181 tttatcgtct ggggacggat ggccttcagc tctacagttc cggtaagacg caaaacctgt
     9241 ccgtgaatgt gggtggtcgg gctgaagtgc atgccggtac gctggaaaat gcggtaatac
     9301 aaggtggaac agtgatcctg ttgtcaccca ccagcgcgga cgaaaatttt gtcgtagagg
     9361 aagatcgcgc accggttgaa ctgaccggga gtgttgcatt actggacggc gcttcaatga
     9421 ttattggcta tggcgcagat ctgcaacaat caacgattac tgtacagcag ggcggtgtgt
     9481 tgattctcga cggcagtacg gtaaaaggtg acggtgtcac ttttattgtt ggtaacatca
     9541 atctgaatgg cggaaaactg tggctgatca ctggtgcggc aacgcatgtg caactgaaag
     9601 tgaaacgcct gcgcggagag ggagcgattt gcctgcaaac cagtgcgaaa gaaatctcac
     9661 ctgacttcat caatgtgaaa ggggaagtta ccggggatat acacgttgag ataacagatg
     9721 ccagtcggca aactctgtgc aacgctctga aattacagcc agacgaagac gggattggcg
     9781 caacgctcca gcctgcgtaa aaacacaggc gcaacccgtg aaggttgcgc cttgtcttta
     9841 ttagcgggat gctcgttgca gaatgataac tgacggcaga cgttgcagga accgcatacg
     9901 cagcatcatc ataatggctg ccgacgtcag gccaataata aagcctatcc agaagcctgc
     9961 tggccccata ggttcaacga ccagatcggt cagtgccaga atatagccgc ttggcaagcc
    10021 cagcacccag taagccgtaa aggtgatata gaaaatggaa cgcgtatctt tataaccacg
    10081 caaaatccca ctgccaatca cctggattga gtcagaaatc tgatataccg ccgccagcaa
    10141 catcaaatgc gcagccagcg ttacaacctc gggattgtcg ttgtacaaca gggcgatttg
    10201 ctcccgcagt gaaaccgtga atatggccgt cagggttgcc atacagacac ccaccataag
    10261 cccggtccgc gcagcggttt gcgcatccag cgttgagccc tgacccagac gataacctac
    10321 gcggatagtt accgctgccg ccagcgacat tggaagcaca aacatcagtg aactaaagtt
    10381 cagggcaatc tggtgtcctg cgacatcaac aataccgagc ggagacacta acagagccac
    10441 gacggcaaac agtgtcactt caaagaatag tgccagcgca atcggcaaac cgagttgaat
    10501 cagtcgtttc ataaccgcag gatcgggttt cgcggtgcct ttttcgttac gaatatcgcg
    10561 catggagcgg gcgcgtttaa tgtaagaaac catggcaagg aacatgaccc aatacaccgc
    10621 cgcagtagcc acgccacaac caacgccacc gagctcaggc ataccgaaat gaccataaat
    10681 aaagatatag ttcaccggaa tgttcaccag caggccgata aagcccatta ccatacccgg
    10741 cttggttttt gccagacctt cacattggtt acgggcaacc tggaagaaca gatagcccgg
    10801 cgcgccccac aacaacgcac gcagataacc cacggctttg tccgccagag ccggatcgat
    10861 gttttccatg gagcggataa tgtaacctgc attccacagc acaagcataa tgagaacgga
    10921 aacaaaacct gccagccaga aaccttgtcg cacctgatgc gcaatgcgct cacgtcgacc
    10981 ggaaccattt aattgcgcga taaccggcgt taatgccagc agcagtccgt gaccaaagag
    11041 gatcgccgga agccagatag aagtaccgat agcgaccgcc gccatgtcgg tggcactata
    11101 gccgcccgcc atcacggtat cgacaaaacc catcgcagtt tgggcgattt gcgcgagaat
    11161 caccgggatt gctaatgcta ataacagacg cgcttcactg atatacttct gcacgtgaac
    11221 accttttatt tgtagttata tgagagacta aaaagccgcc tgaatgggca gcaaaaagaa
    11281 gaagcagggg aaattcagtc tattgtagcg aggatttatt aattctccag tgaaaaaata
    11341 gtcattctta ccccttcact ggtaagggcg tttgccacct gctattgtgc tgaacagaat
    11401 gtcttaactg atttcaggag ttgtaagtat gtttacgggg attgtacagg gcaccgcaaa
    11461 actggtgtcg attgacgaga aaccaaattt tcgtacgcat gtggtggagt tacccgacca
    11521 catgctggac ggcctggaaa caggtgcttc cgtggcgcat aacggttgct gcctgaccgt
    11581 gacggaaatt aacggcaacc atgtcagttt tgacctgatg aaagaaacgt tacgcattac
    11641 caatcttggc gatttaaaag tgggggattg ggtaaacgtt gagcgtgcgg cgaaattcag
    11701 tgatgaaatt ggcggacact taatgtcagg tcatattatg accaccgctg aagtggcgaa
    11761 aatattaacc tcggaaaata atcgccagat ctggtttaaa gtccaggata gtcagttgat
    11821 gaaatatatc ctgtacaaag gatttattgg catcgacggt attagcctga ccgtcggcga
    11881 agtcacgcca acgcgttttt gcgtccattt aattccggaa actctggaac gcacgactct
    11941 tgggaagaaa aaactcggcg cacgcgtcaa cattgaaatt gatccacaaa ctcaggcagt
    12001 ggtagatacg gtagaacgtg tgctggcggc acgagaaaat gccatgaatc aaccaggtac
    12061 agaagcctga tctgaaatcg cccccggaga gggggcgata gaatagcctt tagcgagcga
    12121 ctcgaaggcc gttttcaaca ccgcgtgaga acacgacctg ccagagttga atatcacggg
    12181 cgcggaaagc acctgcacag gcattcagat aataggtaaa cattcgttta aagcgttcac
    12241 tgtagttatc cgcaatttct ggccatgcgg cgaggaatcg ttcataccac gccatcaacg
    12301 tagtatcgta atcagcaccg aagttatgcc agtcttccat cacgaagtgg ggttcgctgg
    12361 attgagcaat ctggcgtaca gagggcaggc aaccgttcgg aaaaatatat ttattaatcc
    12421 agggatcaac attcagatcg gtttttttcg aaccgatagt atggagcagg aatatacctt
    12481 ccggtttcaa attacgatcc accaccgcaa aataggtatc gtaatttttc ggtccgacgt
    12541 gctcgaacat ccccacagaa acaatacgat caaactggtc gttcaggtca cgataatctt
    12601 gcagcaaaat ggtgacatcc aggccttcac agcgttcctg agccattttt tgctgttcgg
    12661 cagaaatggt gacgccgacc acgcttacgt catagttaga tgccatgtag tgcgccagtc
    12721 cgccccagcc gcagccaata tccagtacgc gcatccctgg ttttaactgc aatttttcac
    12781 aaatcatttt gagcttcgcc tgctgggcag attccagatt atcggcatct ttccagtaag
    12841 cgcaggaata ttgcatgaag ggatcaagca tgcggctgaa caagtcatta cccaaatcgt
    12901 aatgctcctt gccgactatc caggcacgtt ttttactctg cagattgaag agacgagcgc
    12961 tggcaatacg cagcgtgtct ttgaaatgat gggggagttg gttctcgaga cctgcgcgta
    13021 agactttgct aaaaaacata tccagtcggt cacattccca ccagccatcc atataacttt
    13081 cgcctaaccc caaagagcct tcttgcagaa cgcgtttaaa aaaatcgggg tttttcacac
    13141 gaatatccgc cggggcagaa ccgttaatgg ctataccggc acggctaagt aattcgttgg
    13201 cgatacggta ccagttgtca tccggtacac tgacttcttc tatacacgat gaactcatag
    13261 tttctccatc actggtcggt gatcagaacc ttaaaacagc gtagacgctt tttgggcttt
    13321 gtgagaaatc tcgcagaaaa aaccgcgagt ctataatccg acgtagaaca gagggaaagg
    13381 aggaaccttt gccgaaatga ccatccatag tgagtcggga acgatcctgt ccccgtaaaa
    13441 acataatatt tatcgtagct ttaacaactc gaaattagta taggccgcta atttcaatca
    13501 tacaacaaaa ttttgttagc agcctaagta taagtatatc gatatagatc agtgtgattc
    13561 gctatgagcg acttcggcat tgccatgatt ctggcagcca acttcttcac aacgttgcat
    13621 catgtaaccc agagcgacca gcactactgt tgataacatc acgctggtgg tggtgagcaa
    13681 tggcgtgctg atactgatca gccaggaaac taccagactt gcgaggaagc acagacccag
    13741 ttgtagagtg ttctgcaacg ctgcggcgcg accagttgcg tgtgggaagg gacgcagcgc
    13801 ctgggcgaca acaatcgggt agatcgcgcc attggcaatc gccatcacac agaatgggat
    13861 caggatttcg accagcgaca catggctaat gaagcctgca gcccaggtcg caatgacgct
    13921 gactgcaaac agcaccagca accacggtaa taactgcttg ccttgccatt tctgcagcgc
    13981 ggcgcgacag ccataaccac caatcagaaa cgcgatagtt tgcgggacat aacttaaacc
    14041 aataactgcc gggctgtagc ccatttcact aaggatgaac ggtgaaccgg tcagccatgc
    14101 aaaaaaactg gctgaacagg ccgcgtatat cagcacgttg ccgcgatagg ttttagaacg
    14161 tagcaggtcg gtaaaggtca gaccatcctg actattgtta cgggccttcg tcgtgggttt
    14221 gagccagaaa ataggcagaa tcagcaccac ggtaatggca aacagggtgg cgaaaatcgc
    14281 ctgccaggaa aaatggacca gcagccagct tcctaacaga ggagccaggg ccggagatag
    14341 acccaccagc ggcatgatgg tcgcaaaaat tcggttaact ttctgtgaag gataataatc
    14401 cgtcactaac gcttgccaga taaccgccgc ggcgcagaca cccacagcct gtacaaaacg
    14461 caataccagc agcgtagcgg cgttttctac ccacagcatc cccagactac ctaacgcaaa
    14521 aattgtcagg ccgattaata acaccggttt acgaccataa cggtcggaga gtggccccca
    14581 cagaagctgg gctgcggcaa aaccggcaag gaacagacta aggctggcac tgacagcaga
    14641 cgcaggcgtt tgcaggtcgg cctgtatggc ggcgaaagca ggcagataca tatcggttgc
    14701 cagaaaaccg agtacgctca aacccgccag ccagactaaa aatcttttcc caggttgcat
    14761 gtatattctc taaatctctc aattaaacac cgccgcaaag tgtagggagt gaaattagtg
    14821 ttgtgaaacg gtaatatttg atgactggtt tcaaaaattt tgcaggcaga ctatgtggtc
    14881 agaatattca ctcgaagttg ttgatgcggt agcgcgtaat ggtagtttta gcgctgcggc
    14941 acaggagctg catcgcgttc cttctgcggt cagctatacc gtgcgtcagc tggaagagtg
    15001 gctggcggtg ccgctctttg aacgacggca ccgtgatgtg gagctgaccg ctgctggagc
    15061 gtggtttctc aaagaagggc gctctgttgt caaaaaaatg cagatcaccc gccagcaatg
    15121 tcagcagata gcgaacggct ggcgcggtca gttagctatc gcagtggata atattgtcag
    15181 gccagaacgt acacggcaga tgatcgttga tttttatcgc cattttgatg atgtcgaact
    15241 tcttgtcttt caggaagtgt tcaacggtgt ctgggatgcg ctttccgacg ggcgcgtgga
    15301 actggcgatt ggcgcaacac gcgcgattcc ggtaggcggt cgttatgcct tccgggatat
    15361 ggggatgcta agctggagtt gcgttgttgc cagccaccac ccgctggcgt tgatgaatgg
    15421 cccattcagc gatgatacgt tgcgcaactg gccgtcgttg gtgcgcgaag acacctcgcg
    15481 aacgctacct aaacgtatta cctggttgct ggataaccaa aaaagagttg tcgtgcctga
    15541 ctgggaatca tcggcaacct gtatctcggc aggattatgc atagggatgg tgccaacaca
    15601 tttcgccaaa ccgtggctta atgaggggaa gtgggtagca cttgaattgg aaaacccctt
    15661 cccggattcg gcatgttgtc tgacatggca gcaaaatgat atgtcgcctg cgttaacctg
    15721 gctgcttgag tatctcggcg atagtgagac gctgaataag gagtggctgc gggagccgga
    15781 agagactccc gcaacgggtg attaacgacg atagtcgcgg aacgggccgt cagccacgga
    15841 gcggcgttca atcaagcgcg gatgcacttc aatggactgc ggttcttcac gtttgttgac
    15901 gatacgatcc aacagcatgt tgaacgctgt ttcacccagc gaatcttttg gctggtggat
    15961 cgtggtcagc gccggcgtaa aatagcgggc gttgcgcacg ttatcataac cgatcagcga
    16021 aacatcctgc gggacgcgca gacccatttc atcagcagca caaagtgcgc ccattgccat
    16081 gatatcgcca ccacagaaga cggcagtagg gcgatgcggc tgcgacagta tttgctgcat
    16141 ggcgcgataa ccagattcgg gttcaaagtc accctgaaca atccagcttt ccggcacctt
    16201 gatcatcgct tcttccatcg ccttcataaa accggcaagg cggcctgcgc cggtgttacg
    16261 ttccagcggg ccggggatga cgccgatttc gcggtgaccg cgttcaatca gataacgccc
    16321 ggccatgtag ccgccttcga acgcgttatc aatgaccgca tcggtgaagt cagcttttgc
    16381 ttcaccccag tccatcacca ccattgggat atggcgatac tcttccagca tcgccagcaa
    16441 cggctctggg tactcagaac acatcaccag cagaccatcg acgcgttttt gcgccatcat
    16501 cgacagataa gcccgctgtt tctcaagatt gttccacgca ttacccagaa tcagggtgta
    16561 acctttctgg aagcaatttt tttcaaccgc ttcaatgatc tcggcaaaat aggccgcttc
    16621 gctgctggtc gccagcaaac cgatagactt ggtgtggtta accttcaggc tacgcgccac
    16681 cgcgctaggg gagtagtgta attctttaat cgctgcccac acggcgttgc gcgtttcttc
    16741 agcgacgaaa cgtgttttgt tgattacgtg tgacacagtt gtagtggaaa cgtttgctcg
    16801 tttcgctaca tcttttattg ttgccattcc atttcactcc agaccctaac ttcagctcct
    16861 gcaaaatcgc aaggtaaacg tttgccttta cacaccttac gcacaacaaa agtgttgcgg
    16921 tacgccggaa aaacgacacg gagcgtcagg aaggggtcaa tggccagtac gcaaatagtg
    16981 taagcgtgga attttggccg atcttgacga aaaggggaag tggtaaaaac acttatcatt
    17041 ataaatgacg ggagattttt tcatcacagt gtgtaaaaat gcgtaatatc actatttgtg
    17101 tggtaataaa aaaggagaaa acttgatgag caccgacctt aaattttcac tggtaacaac
    17161 gattatcgtc ctcggtttga tcgtggccgt gggtttgact gccgcgctgc actgatttcc
    17221 tctcgaggga gcgcgttctc cctcgcatct ccttcctgtt tgttagcaaa atggcaaaag
    17281 tgttttctct ttttgttatt ttcatttttt tgtgattgct gtcatgcttt cgccacttta
    17341 atgaatatcg cgtaatgacg cgaagaggtg gagataaggc atgaaaatta actatccgtt
    17401 gctggcgctg gcgattggcg cgtttggtat cgggacaacg gagttctcgc caatgggctt
    17461 gttgcccgtc attgcgcgcg gtgtggatgt ctcgattccc gctgccggaa tgttaatcag
    17521 tgcctatgca gttggcgtaa tggttggcgc gccgctgatg acgcttctac tttctcatcg
    17581 tgcccgccgc agtgcgttga ttttcctgat ggcaattttc acgctcggca acgtactttc
    17641 cgccatcgcg ccggattata tgaccctgat gctttcacgc attttgacca gcctgaatca
    17701 cggagcattt tttggtttgg gttcagtcgt ggccgcaagc gtggtgccaa aacataaaca
    17761 ggccagcgca gttgccacta tgtttatggg gttaaccctg gcaaatatcg gtggcgtgcc
    17821 ggcggcgacc tggttgggtg aaaccatcgg ctggcggatg tcatttctgg caacggcggg
    17881 gctgggagtg atttcaatgg taagtctgtt cttctcatta cctaaaggtg gtgcaggggc
    17941 acgacctgaa gtgaaaaaag agctggcggt attaatgcgt ccgcaggtgc tgtctgcatt
    18001 gctgacgacg gtactgggag ctggtgcaat gtttactctc tacacctata tctctccggt
    18061 actacaaagt attacccacg caacaccagt gttcgtcacg gcaatgctgg tgctgattgg
    18121 tgtcggattc tctatcggta actatctcgg cggcaaactg gcagatcgtt cagttaacgg
    18181 cacgttgaaa ggctttttgt tgctgctgat ggtgattatg ctggcaatcc cgttcctggc
    18241 ccgcaatgag ttcggcgcag ctattagcat ggtggtgtgg ggcgcagcaa cctttgcggt
    18301 cgtaccgccg ttacagatgc gcgtgatgcg tgtcgccagt gaagcgccgg gtctgtcttc
    18361 atcagtcaat attggtgcct ttaatcttgg aaatgcgctg ggagcagctg ctggtggtgc
    18421 ggtaatttcc gctgggctgg gatacagctt tgtgccggtg atgggagcga ttgtcgcggg
    18481 actggcatta ttgctggtgt ttatgtcagc cagaaaacaa cctgaaacag tttgcgttgc
    18541 taacagctaa ttaaacaaaa acgcagaagg ataaccttct gcgttacagt tgctgacaac
    18601 gtgcgattta tcttgccgaa tgcgctgtta acgcctcatc cgcgttggca tggtaagcga
    18661 agcgcatcag gcaatgctgc atttgccatc agttattatg cagcgagatt tttcgctacg
    18721 aactcccagt tcaccagcgc ccagaagtgc tccagatagc caggacgtgc attgcgatag
    18781 tcgatgtaat aagcgtgttc ccagacatca acggtcagca gcggagtcgc atcggtggtc
    18841 agcggagtac ccgcgttaga ggttgaaacg atagccagtt tgccatcgct gtttttcacc
    18901 agccaggtcc agccagaacc aaagtttttg atcgctgcat cagtaaactg cgctttgaaa
    18961 tcggcaaagc tgccaaaaga tgcggcgata gcttcagcga cttttccagt cggttcgcca
    19021 ccggcgttcg gtgccaggca gttccagtag aaagtatggt tccagacctg agctgcgttg
    19081 ttgaatacgc caccttcaga gctgcgaata atctcttcca gtgatttacc ttcaaacgcg
    19141 gtacctttaa tcaggttgtt caggttagtg acataagtct gatgatgctt gccgtagtga
    19201 tactcgatag tttccgcaga aatgtgcggt gccagagcat ctttagcata tggtagtgca
    19261 ggtaattcga atgacattgc tactctcctt tattattaat ttgcatacgt acaatagcct
    19321 tattgtgcgt atggataggg tagcaaatta aaaggtgaga caaaagatga acttaccctg
    19381 ttgccgtaac aacagggtaa agttttagcg aagtgttttt ggggtcatta cccgacgagc
    19441 gccaacatag tggcgctgcc agtagtcttc actgagagaa gtgatttgaa tttcctgacc
    19501 tgtgcgcggt gactgaataa atttgccgtt gccgacatac acgccgacat gatcggctgt
    19561 gccgcgtccc tgagtacgga aaaagaccag gtcgccgttt ttcagttcac tacgttcgat
    19621 tggcgctgca tcacgcaggt gatacatttc attcgccgta cgcggaatac gaattttcac
    19681 caaatcttta taagcgtaat aaaccaggcc gctgcaatca aaaccggtac gcggtgagct
    19741 gccaccccaa cgatatggct taccaatttg ctgcatcagt ttattcattg ccactttcgt
    19801 agctttttgc accttcgctt tgtgcgcgtc ggcaagagtt cctgacgcgg catttttgac
    19861 tttcacacaa tgcgatttat agcccttacg tttggtacac ttttcggtaa agctggctga
    19921 ggccgtttta ttgacggcgt gtttgctgcg agttttggcg tttttagaag cggtaatgga
    19981 agatttttta acggaagaag cggttttgct tgtggtcgta cttttactgg cggctttttt
    20041 cgctgttttc tgggtctttt tggtggttgc cgtgcttttc tttttatctg cttttttggt
    20101 gatatgagtg gtagcagaac tctccctggc ttgctttgaa gcatgggcca taggcgttaa
    20161 aggcagggtg gtaaaaagta aagcacagag cgtgatcgaa atacggttta tccgcgccac
    20221 tgagcgtccc tctgttaagg caggtctatc atgcctgcgt ctgatttaca aaacttgatg
    20281 attctaatgc atagaagaag agaaagttaa tagcttttat tgttaaaaaa tacgtttcgt
    20341 tggcgagcgc aaaaaaatgc agcagtgaaa gctaaaaatg gttataaata cgccagtttg
    20401 ccgcgcatca gagaagaaac gaatatttga aatgcaacaa atagagcaaa gggataaaat
    20461 agcaaaagcg tgatgaaaat gttattttcc gatgccgcac tgacccgcta caatgtcaga
    20521 ttactgccgt aaagaagttt gaggaagcaa gacaatgagc accactatcg aaaaaatcca
    20581 acgccagatt gctgaaaacc cgatcctgct gtacatgaaa ggttcaccga aactgccgag
    20641 ctgcggtttc tctgcccagg cagtccaggc gcttgccgca tgtggcgaac gttttgccta
    20701 tgttgatatt ctgcagaatc cggacattcg tgcggaactg ccgaaatatg ctaactggcc
    20761 gaccttcccg caactgtggg ttgacggcga gctggtcggc ggttgtgata tcgtgatcga
    20821 aatgtatcag cgtggcgaac tgcagcagct gatcaaagaa actgccgcta aatacaagtc
    20881 tgaagagccg gacgcggaat aatccgtcct gcaatactga cggatgcgaa cgggcatccg
    20941 tcagtccttt ctctatcccc aatccagccc ttgtggcgaa cttgaaaatc ccgcctcacg
    21001 cagcagcgta aacatcggcg tttgccggac cggtagatca ttcacttctg ttagcgtaaa
    21061 gcgcagccgt ggttcgcgac gcagtgcggt agtcagcgcg tggaaaacct ctggggcgag
    21121 taattcctct ttttcctgcc agaccagcat ttttttgcca ccttgcgcca gatagagtaa
    21181 caatttgccg ccagaaacga ccaccagcgc acccgcccga cgcgttggaa ccagcgttgc
    21241 cggatgtgca ggccagggca gaagatttcc ccacacatta gccggatcgt tggcagagag
    21301 cgccactggt gtatagtggc gcgtttgcgt ggcttgtgtc gccagatcgc gcaatcggtc
    21361 aatagtcaga cgttcagcga attgcgcgcc acccagacct tctacaaaac gacctcgcat
    21421 aattcgcccg gagtcttcca tacttcgaca aagcgtttgc atcgatggaa acccgccagg
    21481 gatattttcg gctatcaccg cctgacgact gatgatgccg tagcggtcga gcatattttc
    21541 cgccagcgcc agcatccttt cggtatcgtt tagtggctcc acctgcaata acgaccagcg
    21601 tccagccaga tttggtgtgt tgtaagatac cagcggcgag acgggttgcg catagacagg
    21661 acgtccacga cgagcctggt gactgcggcg agttgaggtg cgtgcgttgg aactgctgcg
    21721 ggtgagggcg cgtaacggtg cccaaatgtc gctggtgatg acgccttgcc agaccagcgc
    21781 ccataacgcc tcttgcaggg cagagagatc aaccgattcg ccgattttgt cgcgtatccg
    21841 ttggctgatt tgttgtgcaa accaggctcc tccgtcagcc agaacagcga ctatcgcttg
    21901 ttgcagcgcc gaacgattcg cctgatccgc ttcggcggga gtgaacgatt ctgcagcata
    21961 ttcctgtaga tgcagtgcca ccaggccgtc atcttcaccc agtttttttt gccccgacca
    22021 gataaccgca ccggttgcca gtaattcatc gagcatttct gacgaatagt cgcgtacgcg
    22081 ggcaggcagg atctggcttt cccagagtga ggcgggtaaa ccgactccgg caagctgttc
    22141 gatcacccgc atcacgccat ctacgccctc ataaacgcct ggcgatgttg aggcaaagag
    22201 cgccgggcta ccatcggtgg cgggtaatac gccctgacgt tccagcagca atcgcgcata
    22261 ggtcgtggct gcaacgggac gcgtcgcttc tctggcggct tgcagcgagc gcaaacgcag
    22321 acgacgaaat acttcatcgc tcacccagat gtcttgttgc agattcatca ccagaccctg
    22381 ttcacgcagt tgctgaagct gctcttcgac aatggcaata ccgagactaa actcatgagc
    22441 cagttgttca gccgtgacca gagcatgagc ccggagatag cgcagaaaga gatcgcgaag
    22501 cgggtaactg actctatgta aataaatctc tggcaatgac tctggtagtc gtacgccgag
    22561 ggcatcacgc agcctggcgg catcatccat acaggcaaga cgctcctgtc cgctaatcat
    22621 cgctgggaag attcgtttta ctgcaagaag attttccaga tacgacgcaa cctcttcact
    22681 gctgcctgta tgccgttgcg ccaggtcttc aacggtcatt ggccccagtt cgcgcagcag
    22741 gtcgaacaat ccttcttcac ctttcgctct tctgccagga gccagtcgtt gcaactcttc
    22801 ttccacctgg cgaatgacct gcgggtcgag taattccccc ggatcgacct gtccgagtag
    22861 attgcgcagt aactcgctgt ccagcgacag tacggatgcc cggcgctctg ccagcggggc
    22921 gtcgctctgg tacataaatt ccgcgacata gccgaacaat aaacttgtgg cgaaaggcga
    22981 gggcgtagtg gtcgttacat cggatatttg aatttcgcca ccgttcaggc gacgcatcaa
    23041 acgttccagt gcgggaagat cataaacatc ttgcagacat tcgcgtaggg tttcgagaat
    23101 gaccggaaaa tccggatatc cctgagcgat ttccagcaac tgactggcgc gcagccgttg
    23161 ttgccaaagc ggggtgcgat ggcccggagt gcgccccggc attaataatg cccgcgcggc
    23221 gcattcgcga aaacgggcgg cgaaaagtgc cgagctgcct accgcctcgc ggacaatttg
    23281 cagcaacttt tctggttcaa acaaaaaaat cgcggcgtcg ggcaatttac catcagtgtc
    23341 aggaatgcgc gcaacaatgc cgtcatcact ggcgaccaca gacgcgtcag cgccccatag
    23401 ggcatgtatt cgcccggcaa tcgccagcgc ccagggttca tgcacccgtc ttccataggg
    23461 agagtgcaaa ataatacgcc agtcgccaat ttcatcacgg caccgttcga ggaccagatg
    23521 gcgactcccc ggaacgatgc ccgtcgcgtt gcgttgctcg tcaatcaacc cctgaatatt
    23581 ggcgatcgta ttttcttctg ccagccacgg gggaatagtc ccggaaaaga acgcgccatc
    23641 cgccagcaaa tgaagaaaat cgccgatcat ctcgcctaat tcagccggac gtccgttacc
    23701 ttcaccacgc cagaagggga gccgggcaga acgacccgga gcaggagtca caatcacctg
    23761 atcgcgggtg atttgctgga tccgccatga ggtagcgccg agagtgataa tgtcgttcac
    23821 ccgcgactca tataccatct cctcatccag ttcacccacc cgccgcgaac cggcctgttc
    23881 ttcaccttcg ggtaataaca cgctatacat gccacgatcc ggaatggtgc cgccgctggt
    23941 aaccgccaac aattgagcgc caggtcgggc ggtcaatatc ccggtctccc tgttccagac
    24001 cagtttgggg cgaaaagcag aaaaatcgcc agagggatag cgcccggaaa gcatatccag
    24061 cgtggcgtca aaaacacgtc ttggcagatc tttccacggt gcggcacggc gtacgcggga
    24121 gtaccattcg tctacctgta atgcctccat cgccgcggcg gcaacggttt gctgcgcaag
    24181 gacgtcgagt ggattatgcg gcggtgtcag gttttccagc ctgcctgcga acatacactc
    24241 tacaatgact gcggaatcga ctaagtcacg ccgggtacga gggaaaaaca gccctttaga
    24301 tacaccgcca acctgatgtc cggcgcgacc aatgcgttgt aacccactgg caacagaaag
    24361 cggcgttgcc acctgaatca ccagatccac tgcgcccata tcaatcccca gttcgagact
    24421 ggaggttgcg accacgcagc gtaactcacc cgatttcagc gcctgctcgg tgattgctcg
    24481 ttgttcttta gagacggagc cgtggtgtga gcgggcaata aaaacgtcgc tactttgtac
    24541 acggttagag gttgcgccgg aggtcgactc gaaatgggcc gcatcaacgg cgatagacgg
    24601 ggaacgctgt aatcgtgcgg cgtaaagctc atttaatcgt gccgtcagtt tttccgccag
    24661 cccacgtgaa ttagtaaaga caatggtcga gcgatggcgc aacacttcat caaggatacc
    24721 cgtttcaata tatggccaga tggagccttc ccggccggca tggctgtctt cgccggtgct
    24781 gctggcgacc gatgagacat catccatatt ggcgaccggt acgacaattc gtatctgcgg
    24841 atggcgcatt gcgggcgggt tgactaccgt aaccgggcga tcgccaccaa gaaatgctgc
    24901 cacatcgctg gctgagcgca cagtggcaga aaggccaatt cgctgtgctg aggtgtggag
    24961 cagcgcatcg agccgctcca gacttaacgc cagatgcgca ccacgtttac tgcccgctac
    25021 cgcgtggact tcatcaataa ttaccgtttc gacgccgcgt agcgtttcgc gcgcgcggga
    25081 ggtcagcatc agatagagtg attcgggtgt ggtgatcaga atatccggcg gattacgggt
    25141 gagtttgctg cgttcctgtg caggcgtatc gccagtacgg atccctacgc gaagattgac
    25201 ttccgtttcg ccgcgccgcc gccgttcatc ggcaataccc ttcaacggga gctgcaagtt
    25261 gcgctgaacg tcggtgccca gagcttttat cggtgaaata tagaggatgc gtgaggtttt
    25321 acgcttatgc gcctcgcagg tatcttcgcc gccttcgcgg aagagccgat cgagggcgta
    25381 gagaaatgct gccagcgttt tcccggagcc ggtcggtgca atcaccagcg catgttcgct
    25441 tcgcgccgcc acatgccagg tttgcgactg gacagcggtc ggctgtttaa aggcgcgaag
    25501 aaaccagtcg cgggtcgccg gtgaaaacac gtccggcagg agcgatgaag agtctggatt
    25561 atctgccatt aacgctattc cccgtgaata tcatgcagga tgcgtggaat agcctcacta
    25621 tagatgcctg aatcattgca tgtcatcagg catcgactcg attacacctc ttcggcggca
    25681 ggtagcggcc agcctcccag acgtttccag cggttgacga tttcacaaaa cagcacagca
    25741 gtgcgttcgg tgtcgtacag cgcggagtgc gcctgggtgc tgtcgaagtc catgccagcg
    25801 gtctggcaag cctttgacaa tacggtttgt ccgagtgcca gcccggccag tgcagcagtg
    25861 tcaaaagtgg cgaaagggtg gaacgggtta cgtttcagtg aggcgcgttc tgcggcggcc
    25921 atcataaagc tgtgatcaaa attggcattg tgcgccacca taatggcgcg gttacagccg
    25981 ctcgctttaa tacctttacg tacaacttta aaaatttcgt gcagcgcctc gtattcgctg
    26041 accgcgccgc gatcgggatc gttcgggtca atgccgttga aggcgagggc ttctggttgc
    26101 aaatttgcgc cgacaaatgg ttcgacgtgg aaatgtaatg tggtgtccgg catcagccag
    26161 ccttgttcat ccattttcag ggtgatggcg gcaatctcaa gcagcgcatc ggttttggcg
    26221 ttaaatccgg ctgtttcaac atcgatcaca acaggataaa aaccacgaaa acggtcgcac
    26281 agaccggtaa gttgagcgtt atcggacatc tgattctctt aatacggata aattgcagcg
    26341 cgcattatga caaatattac ttgtcgatgc agtaaagatg cgggcgcgat gagttcacgc
    26401 ccggcaggag attagttgcc cagaccgcga ccggcgtctt tctcttcgat taactcaatt
    26461 ttgtaaccgt ccggatcttc cacaaacgcg ataaccgtag taccgccttt taccggaccc
    26521 gcttcacggg tcacgttacc cccgttttga cggatttttt cgcacgcttc agcggcgtta
    26581 tctacgctaa gcgcgatgtg accataagca gtgccgagtt cgtatttatc cacgccccag
    26641 ttgtaggtca gttcaatcac cgcttcttcg gtttccgggc cgtagccaac aaacgccagt
    26701 gagtatttgt attccgggtt ttcgctggta cgcagcagtt tcatgcccag cactttggta
    26761 taaaaatcga tggagcgttg cagatcgcca acgcgcagca tggtatgaag aagacgcatc
    26821 tttttatcct caaaatggct aacagattca aaatgttgtt ttagtatagc ggcggcttta
    26881 cgccgctcgc aatgttggat tacaacgtcg ggtaatcggt atagccttcc gcgccgccac
    26941 cgtagaaact ttcggcacgc tgtgggttaa gctcagcttt gcgctgcaag cgggcgacca
    27001 gatccgggtt cgcaatccag tcacgaccaa atgccaccgc atcaattaac cctttgccga
    27061 tcagcgtttc agctttttct actgtgtatg cacctgcgcc gataatcgga ccgtggaaac
    27121 gggcgcgtac tttttcgcgg aacgcatcag tatacggttc accccccgcc caatctggtt
    27181 ctgacatatg cagataagca atgccgcgtt tacccagttg ttcaatcaga tacagtgcat
    27241 cggcttcttc attcgggccg ttatccgtgt tctggaaagt accgattggc gaaatgcgaa
    27301 tgccaatgcg atcggcaccc cattcttcaa tcccggcatc gaccacttcc agtaccagac
    27361 gtgcgcgatt ttccacgctg ccgccgtact gatcggtacg atggtttgaa gaaggagaaa
    27421 ggaactgatg cagcaaataa ccgtgagcag agtggagctc taccagatca aaaccggctt
    27481 cacgcgcgtt agcaatggcc tgacggaaat cattgacgat acctggaatc tcttccagtt
    27541 caagcgcacg cggcatggat gtttcaacac ggatcgcctg accattttca tcgcgcagag
    27601 aagtacgtgt tcccgcgcta agtgctgaag gcgctaccgg tgcctgaccg ccaggttgca
    27661 ggctggcgtg agaaatgcgt ccggtgtgcc acagctgcac ggccatatga ccattttcag
    27721 catgaacgcc agcggtgatt tttttccatg cggcaatttg ctccggacta tggatgccag
    27781 gcgcacctgc atatcctttt gcctgggcag aaatttgcgt ggcttcacta ataatcaaac
    27841 cggcactggc acgttggcga tagtattccg ccatcaacgg ggtaggaatg tcacccggtt
    27901 caatactgcg cagacgcgtc agcggtgcca taaaaatacg gtttgccgcc gtgatcgcgc
    27961 ccactttcag tggggaatac agtttttcag atgacataaa ggctcccggt cgtctggtga
    28021 taaaaaatgc ctgctaaacg gcaggcgtcg caataatgtt ttttacatgg gccagcgcgt
    28081 tttccagtgg ctcgaaactg cgcgaaattt tggcctgcag attcgcaccc agccatagtg
    28141 cgtaaagcac ttgtgcctgt tgtagcggtt cgccacaaaa ggttaaacaa tggttctcac
    28201 ggccattttc cagcgcctga gagagcaggg cgatcacgcc gcgagcacct ttatccatcg
    28261 cgctgcgcat atcttctgac agatcgcaca cttcggcaga gagttttact gtcaggcaac
    28321 cactgatggt tccatgttgg caaaactggt tcagtgtttg ctggtaataa gccagtatgc
    28381 ggtcgcggta gttaccttcg ccggattgca gcaactcagt cagtcgctgg tgatatgcgg
    28441 cgtaatgacg ctcaagcatg gcaacgccaa acgcttcttt agagcgaaag tagtgataga
    28501 aggacccttt cggcacttca gcggttttta gtaattcgct tagccccatc ccggtgaatc
    28561 cacgttgcag gcaaagttgc tcgcccgtcg ccaggagatg ttcgcgagta tcatgttcgg
    28621 tgtgtttgtt catgcgttgg agtgtagtag accagtcggt ctagtgcaag caaagttgct
    28681 actttggaca ttaacagctt caataatggt aataatctta tctgaggagg gcgaagtggc
    28741 ggagcaatta gagttctttc ccgtccagag cccgtgccgg ggaatttgcc agtctgacga
    28801 acgcgggttt tgtcgcggct gttttcgtag tcgtgatgag cgttttaact ggaataaaat
    28861 gagcgatggc gaaaaacaag aggtgctgcg cctttgtcgg cagcgattaa tgcgcaaatt
    28921 acgcgcaaat aagccagcgt catcagacga accggagcaa ccatcactct tttgaaccta
    28981 atcttgcgta tactcctctc atatctgata agaggaagcg attatggttc agcgtattac
    29041 tattgcgccg caaggcccgg agttttcccg ttttgtgatg ggctactggc gattgatgga
    29101 ctggaatatg tccgcccgcc agctggtcag ttttattgaa gagcatctgg atctcggcgt
    29161 gaccaccgtg gaccatgctg atatttatgg tggctatcag tgcgaagcgg cgtttggcga
    29221 ggcactgaaa ctggcacctc acctgcgtga acggatggaa atcgtcagta aatgcggtat
    29281 cgcgacgacc gcgcgtgaag aaaacgtcat tggtcattac atcactgacc gcgatcacat
    29341 cattaagagc gccgaacagt cgctaattaa tctcgcgacc gatcatctgg atctgctgtt
    29401 aatccaccga ccagacccgt taatggatgc cgatgaagtg gcggacgcgt tcaaacatct
    29461 gcatcagagc ggcaaagtgc gtcattttgg cgtatcgaac tttacgcctg cgcaatttgc
    29521 cctgttgcaa tcacgtctgc cgtttaccct tgccactaat caggtggaaa tatccccggt
    29581 gcatcagccg ttactgctgg atggcacgct cgaccaacta caacaactgc gtgttcgtcc
    29641 gatggcgtgg tcctgccttg gtggtggtcg tctgtttaat gatgattatt tccagccgct
    29701 gcgtgatgaa ctggctgtgg tggcagagga gttaaacgcg ggctcgattg aacaggtggt
    29761 ttacgcctgg gtattacgtt taccatcgca gccgctgcca attatcggtt caggtaaaat
    29821 tgagcgcgta cgggcagctg tcgaagcaga aacactgaaa atgacccgtc aacaatggtt
    29881 tcgtatccgt aaagcggcac tggggtacga cgtaccgtaa gcacttttag gaatagccgc
    29941 cgttcaaaaa tgtgtcactg gtttacactt attcaggaat gcacaatgaa cggaggtcct
    30001 atgaaacgtt ttagtctggc tattctggcg ctggttgttg caaccggcgc acaagctgcc
    30061 agtgaaaaag tcgagatgaa cctcgtcacg tcgcaagggg tagggcagtc aattggtagc
    30121 gtcaccatta ctgaaaccga taaaggtctg gagttttcgc ccgatctgaa agcattaccc
    30181 cccggtgaac atggcttcca tattcatgcc aaaggaagct gccagccagc caccaaagat
    30241 ggcaaagcca gcgccgcgga atccgcaggc gggcatcttg atccacaaaa taccggtaaa
    30301 catgaagggc cagaaggtgc cgggcattta ggcgatctgc ctgcactggt cgtcaataat
    30361 gacggcaaag ctaccgatgc cgtcatcgcg cctcgtctga aatcactgga tgaaatcaaa
    30421 gacaaagcgc tgatggtcca cgttggcggc gataatatgt ccgatcaacc taaaccgctg
    30481 ggcggtggcg gtgaacgcta tgcctgtggt gtaattaagt aattacgagg ccagcgtacc
    30541 ttgcggtggt gcttgctcaa gttgcgaaag cgagcagtac agccgccaga caattgccgc
    30601 cagctcacgg gcggcaggtt gatgatgacg ggcaaggctg ttgcaaatcc gctgtaattc
    30661 ttcaagtgtg gccgccagtg atttttgctg aacgccacgc tcactcatca ctccccgcaa
    30721 cagtgaaata cagttatccc gtactcgcga taacggatcg gaacgcgatt cccagtcgcg
    30781 caattgccag acaacatgag aacagttcag cagcactaca ccccagcgta ataaccaacg
    30841 gcgagccagc gcatcctggc tgttactcaa ctgactgacg tgatgataag tgagcgattc
    30901 aaattcgctt tcactcagtg ttggatggcg gcttagctga tcgacaaaat cccggcgcag
    30961 cgcgcgaata tggcggcggc ttttacgagc atccgatcct ggacgcagaa tggcgaacgc
    31021 tagccaagcc agcgcaacgc caacgatttt tgccagatta tcgttaagaa aatcagcaaa
    31081 atcatacacc gggggattag tgacagcgat aaacgaaccc ataaaaacaa tcagttgccc
    31141 ccacagtgcg gcaaatttgg gcatctgcga tttaagaagc tgcattgtcg ccagcagtgg
    31201 aaagagaaac agtaaaaatt gccacagatc gctaatctgg accatcaggc caaatttgac
    31261 cacaaagctg aatagcgaaa gtaacaccag cgtgcgcatc agcagtgaca acgacttaaa
    31321 cggtgctgcg acggcggagt agagtacgca gctaattgct gccagcgtta atgcattggc
    31381 accgacatcc cattgcgatg caatactcca tgcgccaatc atcatcaacg tacaaaatgt
    31441 acgcagcccg ctccacatag cttcggcgtt gtcggtatga cgagccagag cggatgtccg
    31501 tgcgagtctg gcatgatcat ctacaccgct ttgcagacga tgtaattcct gactactttg
    31561 cagataaagg cggcaaaaat aacgtagtcg ctgccagaag gcgacgtgcc ggtagtcggc
    31621 gacgttggtc gggcgtagcg gggcgataat acgtgcgacg gtgtaagcat ctgtttgcga
    31681 actggcgagc gccgtcagca attgttcgag aatttctcgc gtggcacctg gcggtgaggg
    31741 ccagttgagc aacatacgtc gcaggctgga gatgacactg gtcatacgta attgctggtg
    31801 gagtagcgca ttaaggcgcg cgttttgctg gcgaaaacga tagtggctcc agaaagcctg
    31861 gatacgcagc aaattcatgg tcagtatctg cccaatcacc ccctcatgtg ctgcacgaat
    31921 ggcatcgttt gtttcaggct gccagagtaa actggcatgt tccagtaatc gggcgtgcat
    31981 gtttttcaat gcggttaaaa gggctgtagc atcggaactg ctaggcagga tcatcatcat
    32041 catgccgccg cacaaaatac cgactatcac ctcgcaaacg cgcgcctgag cgatatccca
    32101 cagctggctg gcctcagtaa tattaaccat cggaaaggcg atgatggcag ccgtgtagcc
    32161 cgccagttga aatgcatacg cgacgttatt cgtgaagtgc gcacaggccc aggtacaaaa
    32221 gccaagccac gccgacatgc tcaatagaaa aaaccacggc tcattgagcg tatgcccggc
    32281 aagaagcagt gccgcaatgg ctcccagtaa actgccagcg atgcgtccga ggcttttgct
    32341 gatgacaccg ccaacggtgg gaaagctaac cactgcagcc gaggtcatcg cccaataggg
    32401 ttcatccaga ttcaaataat aggcaaccgt cagcgccaga cacatggcaa tggtattgcg
    32461 taacgcataa cgccattgcg ccagcgtggc cttgaaccag ggcaaattgc gcaaggacca
    32521 tgacgatgcg ttcattattg acctacggca atgctacagg tggtgcccga caccagcgtg
    32581 acatcgcctg gaactttatc cagcgcaaag cggacgggaa cgcgttgggc gagacgaacc
    32641 caggggacgt taggtttcac atccggaata aggcttgagt cactttcaac gctttgatca
    32701 taaatcgccc gaccgatact ggaaacgtga ccccgtaacg ttttgttatc actatagagg
    32761 gtaatttgtg ctggtgcacc ttcgcggata tggcgcaact tggtttcttc aaaataacca
    32821 atgacgtaaa acgagtggct gtcgacaagg gcaaacagcg gtttcccggt gtcagcgtaa
    32881 tcgccgatgc gggtagtgag gttagtcacc caaccactca ccggggcgcg aatttccgtt
    32941 tgcgccagtt gccattgtgt ctgtttcagc gtggcctgtg cggcattaac actggcctgc
    33001 atcgctttaa cattgaggtt agcggtatcg agttcttcgg cagaaataaa attttgtgag
    33061 agatgacgac gacgattcgc ttcgttattg gcttttgcga ggtcagattg cgctttcgcc
    33121 agctgagcct gtgcgttcag ctcggcgatc tgaaagggcg ttttatcgat cgtgagcaga
    33181 agatcccccg cgttaaccag ttggttgtct tttatattca gctcaacaat acgtcccgac
    33241 acctgtgggg tgatagaaac cttttctgcg cgtattttcc cgtcgcgtgt ccacggagat
    33301 tgcatgtaat aattccacag ccaccatccg gcaagaaccg caactatcgc tacaatgatt
    33361 gttgagaaat acttaattgt tttaattgac atagttacca cgcaatcagt attgccagag
    33421 caaggcaaac gcaaatcgca aacagcgata aatccattaa caagggatgc cagatgtcac
    33481 cggcgtagat ccagccacga agcaggcggt gtacgacaag ccagatgacg aatccaaacg
    33541 cgaaggcttt gaaaaacgga ggaaaataga cggacgcacc gaacaccaga tcttgtaagg
    33601 gcaatcctgt tgcattgagc ataaacttca caaagtagat tcctttacga ccgaatatat
    33661 tgcgttagat taataaatat tctttaagtg cgaaaaattt acgcgcaatt tctgaaaaat
    33721 atgtctgacg gtaaccaaat gcagcaatac atttgtttta gcaatacaat tgctgcacac
    33781 tattctaaaa gccgcataat atcttagcaa gctaattata aggagatgaa attggaatcg
    33841 ccactaggtt ctgatctggc acggttggtg cgcatatggc gtgctctgat agaccatcgc
    33901 ctgaaaccgc tggagttaac acaaacccat tgggttacgt tacacaatat ccatcagtta
    33961 cctccagacc agtcgcaaat tcaactggca aaagcgattg gcatcgagca gccatcactg
    34021 gtccgtactc tggaccaact ggaagaaaaa gggttaattt cgcgtcaaac ttgtgccagc
    34081 gatcgtcggg ctaaacgtat taaactgacg gaaaaggcag agccactgat cagcgaaatg
    34141 gaagctgtta ttaacaaaac ccgcgcggaa atattacatg gcatctccgc agaggaactg
    34201 gagcaactga ttacgctcat cgcaaaactt gagcataata tcattgagtt acaggccaaa
    34261 gggtgaaatg aagggggcgt gtggtcagta acctgaccac acgcaaactt atttagcgcg
    34321 gagaaacggt cacctgactg ccattgctgg ccagtacgac acgttggccc ggagagaaac
    34381 gagtgttgcc ttgtttctgt accaccatga tggtattacc atcgtcttta cgaatttcca
    34441 gctcgacacc ctgcgttttg ttcattgcac tctgtacgcc ctgaccagct acgccacctg
    34501 caacagcgcc tgctgcagta gccagagaac gcccggttcc gccaccaaca gtattcccca
    34561 ggaaaccacc aagaacagca ccgccaattg caccgataac gttggaatca tcaccgccct
    34621 gaatctgtac cggacgtacg ttaacgatgg tgccatagct gacattctgt acttgtttcg
    34681 cttcagaagc ggtataaaca tcccctgaca gggtgtcgtt attaacacaa ccgacaagag
    34741 acagacctac cattgaaaca accaatacgc gtttaatcat tgaaaaatct cctgttcacc
    34801 atgaaacgcc acgcaagcat ccctcatggt caaagtatat ggcatatgtg aatccatggt
    34861 tacatgttct accaaatatg agcaaatcat aatgaaagta ggatcaacca attataaaca
    34921 aaacattcat gatgattatt gatttgaaga taatgtttta ctaccaacgg taaaaatcgg
    34981 tcattccgca tggtattcac gaaaagttta tgtttgagtg gtgcgcaaac gtcagattga
    35041 aaaaggatga actatgaaat cgggccgctt tattggcgtt atgtcaggca ccagccttga
    35101 tggtgttgat gttgtgttgg cgacaataga tgaacaccgg gtcgcacagc tggcaagctt
    35161 gagctggccg atcccggtgt ctctgaaaca ggctgtactg gatatttgcc agggccagca
    35221 gcttacactt tcgcagtttg gacagcttga tactcaactc gggcgacttt ttgctgatgc
    35281 ggtcaatgcc ttgcttaagg aacaaaacct gcaggcgaga gatatagttg cgatcggctg
    35341 tcacggtcaa accgtctggc atgaaccgac gggcgtggca ccacacactt tacagattgg
    35401 cgataacaat caaattgtgg cacgcaccgg aattacggtt gtcggtgatt ttcgccgtcg
    35461 cgatattgcc ttgggaggac aaggcgcacc gctggtacct gcgttccatc atgccttgct
    35521 ggctcactca accgagcgac gaatggtgct caatattggc ggcatcgcca atctgtcact
    35581 gctcattcct gggcagccgg ttggcggcta cgataccggt cctggtaaca tgctgatgga
    35641 tgcctggatc tggcgtcagg ccggtaaacc ttacgataaa gatgccgagt gggcacgggc
    35701 gggtaaagtt attctcccac tgctgcaaaa tatgctcagc gacccatatt tctcgcaacc
    35761 tgcaccgaaa agcaccggac gcgaatactt taactacggc tggctggagc gccatttacg
    35821 ccattttccg ggtgttgatc cccgtgatgt tcaggccaca ctggcagaac tcaccgccgt
    35881 gaccatttct gaacaagttt tgttgagcgg tggctgcgaa cgattgatgg tatgtggtgg
    35941 aggtagtcgt aatccgctac tcatggcgcg tctggcggca ttactgccag gcacagaagt
    36001 caccaccacc gatgccgttg gcattagtgg cgatgacatg gaagcattgg ctttcgcctg
    36061 gcttgcctgg cggacgctgg cgggattacc aggaaatctg ccttccgtca ctggcgcaag
    36121 ccaggagacg gtactggggg ctattttccc tgctaacccg tgatatcaga gttaactgaa
    36181 tttttcttac cgcgtctgcc gttacacttg gaacgttagg gagggcgtat tgccctccag
    36241 accaggaaag tcttcgggaa atgtctatga aaaaactgtt actgatctgt ttgccggtgc
    36301 ttctcaccgg ctgtagcgcg ttcaatcaac tggttgagca catgcaaacc gctacgctgg
    36361 aataccagtg tgatgaaaaa ccgttgacgg tcaaactgaa taatccgcgc caggaagtca
    36421 gttttgttta cgataatcaa ctactgcatc tcaaacaggg catttcagcg tctggtgcac
    36481 gttacactga cggaatctat gttttctggt cgaaaggcga tgaagcgact gtctataaac
    36541 gcgaccgcat cgtattgaat aactgtcagt tacaaaatcc acagcgttga gatttttcca
    36601 ggggcggcgc acaatagcgt cacccactga caatccgtaa agaaaaccat gtctgataac
    36661 gacgaattgc agcaaatcgc gcatctgcgc cgtgaataca ccaaaggcgg gttacgccgt
    36721 cgcgatcttc ccgccgatcc attaaccctt tttgaacgtt ggctctctca ggcgtgtgaa
    36781 gccaaactgg cagaccctac cgcgatggtg gtcgctaccg tggatgaaca tgctcagcct
    36841 tatcaacgca tcgttttact caaacattac gacgaaaaag gcatggtgtt ttacaccaac
    36901 ctcggtagcc gtaaagcaca tcaacttgaa aataatccgc gcgttagcct gctgttcccg
    36961 tggcataccc ttgaacgcca ggtgatggtg atcggtaaag cagaacgact ttcgactctc
    37021 gaagtgatga aatattttca tagccgcccg cgtgatagcc agattggtgc atgggtttcg
    37081 aagcagtcca gtcgcatttc tgcccgcggt atccttgaaa gtaaattcct ggagctgaag
    37141 cagaagtttc aacagggcga agtgccattg ccgagctttt ggggcggttt tcgcgtcagc
    37201 cttgaacaga ttgagttctg gcagggcggt gagcatcgcc tgcatgaccg ctttttgtac
    37261 cagcgagaaa atgatgcgtg gaagattgat cgtcttgcac cctgaaaaga tgcaaaaatc
    37321 ttgctttaat cgctggtact cctgattctg gcactttatt ctatgtctct ttcgcatctg
    37381 gcgaaaagtc gtgtaccggc aaaggtgcag tcgttatata catggagatt ttgatggcaa
    37441 gcagtaactt gattaaacaa ttgcaagagc gggggctggt agcccaggtg acggacgagg
    37501 aagcgttagc agagcgactg gcgcaaggcc cgatcgcgct ctattgcggc ttcgatccta
    37561 ccgctgacag cttgcatttg gggcatcttg ttccattgtt atgcctgaaa cgcttccagc
    37621 aggcgggcca caagccggtt gcgctggtag gcggcgcgac gggtctgatt ggcgacccga
    37681 gcttcaaagc tgccgagcgt aagctgaaca ccgaagaaac tgttcaggag tgggtggaca
    37741 aaatccgtaa gcaggttgcc ccgttcctcg atttcgactg tggagaaaac tctgctatcg
    37801 cggcgaacaa ctatgactgg ttcggcaata tgaatgtgct gaccttcctg cgcgatattg
    37861 gcaaacactt ctccgttaac cagatgatca acaaagaagc ggttaagcag cgtctcaacc
    37921 gtgaagatca ggggatttcg ttcactgagt tttcctacaa cctgttgcag ggttatgact
    37981 tcgcctgtct gaacaaacag tacggtgtgg tgctgcaaat tggtggttct gaccagtggg
    38041 gtaacatcac ttctggtatc gacctgaccc gtcgtctgca tcagaatcag gtgtttggcc
    38101 tgaccgttcc gctgatcact aaagcagatg gcaccaaatt tggtaaaact gaaggcggcg
    38161 cagtctggtt ggatccgaag aaaaccagcc cgtacaaatt ctaccagttc tggatcaaca
    38221 ctgcggatgc cgacgtttac cgcttcctga agttcttcac ctttatgagc attgaagaga
    38281 tcaacgccct ggaagaagaa gataaaaaca gcggtaaagc accgcgcgcc cagtatgtac
    38341 tggcggagca ggtgactcgt ctggttcacg gtgaagaagg tttacaggcg gcaaaacgta
    38401 ttaccgaatg cctgttcagc ggttctttga gtgcgctgag tgaagcggac ttcgaacagc
    38461 tggcgcagga cggcgtaccg atggttgaga tggaaaaggg cgcagacctg atgcaggcgc
    38521 tggtcgattc tgaactgcaa ccttcccgtg gtcaggcgcg taaaactatc gcctccaatg
    38581 ccatcaccat taacggtgaa aaacagtccg atcctgaata cttctttaaa gaagaagatc
    38641 gtctgtttgg tcgttttacc ttactgcgtc gcggcaaaaa gaattactgt ctgatttgct
    38701 ggaaataatg cattaagtgg aaagggggag tgagaaatca ctccccctgg tttttataca
    38761 gggaacatga tgaaaaatat tctcgctatc cagtctcacg ttgtttatgg tcatgcgggt
    38821 aacagtgcgg cagagtttcc tatgcgccgc ctgggcgcga acgtctggcc gctgaacacc
    38881 gttcaatttt ctaatcacac ccaatacggc aaatggactg gctgcgtgat gccgcccagc
    38941 catttaaccg aaattgtgca aggcattgcc gccattgata aattacacac ctgtgatgcc
    39001 gtgttaagtg gctatctggg atcggcggag cagggtgaac atatcctcgg tatcgtccgt
    39061 caggtgaaag ccgcgaatcc gcaggcgaaa tatttttgcg atccggtaat gggtcatccg
    39121 gaaaaaggct gtatcgttgc accgggtgtc gcagagtttc atgtgcggca cggtttgcct
    39181 gccagcgata tcattgcgcc gaatctggtt gagctggaaa tactctgtga gcatgcggta
    39241 aataacgtcg aagaagcggt tctggcagcg cgcgaactca ttgcgcaagg gccacaaatt
    39301 gtgttggtta aacacctggc gcgagctggc tacagccgtg accgttttga aatgctgctg
    39361 gtcaccgccg atgaagcctg gcatatcagc cgtccgctgg tggattttgg tatgcgccag
    39421 ccggtaggtg ttggtgatgt gacgagcggt ttactgctgg tgaaactgct tcagggggca
    39481 acgctgcagg aggcgctgga acatgtgacc gctgcagtct acgaaatcat ggtgaccacc
    39541 aaagcaatgc aggaatatga gctgcaagtg gtggctgctc aggatcgtat tgccaaacca
    39601 gaacattact tcagcgcaac aaagctctga aatatctcat ttcggcccac aacgacctgt
    39661 gggccgatgg atattacttt aagccttccg ctgacagcgc gtcttgtact tccggacgtt
    39721 cagccatacg ttgcataaat gctgcaatgt gctctaaccc ttccagattc agtttcaccg
    39781 cgtatgccca gcgcagaacc gtaaacagat aggcatcagc aattgtaaat ctttgcccgc
    39841 agatccagtg ctcatccttc agtgcctcgt tcacatattg cagcttcttc tccagctgcg
    39901 cgcgaactgt cggtttgtac tcttccggtg tatcagggcg aaacagaggt gtgaaacctt
    39961 tatgcagctc ggtggcgatg taattcagcc attcgatggt tttatagcgg gaaatactgt
    40021 ttaccggtgc cagcaactgg cggtcgggga cgctgtcggc aagatactgc ataatcgcta
    40081 cgccttccgt cagcaaagta ccgtcatcca gcagcactgc aggcacctgc cccttagggt
    40141 taacgacaaa gtaatcgtca ccgttttcga gacgtttttt cattaaatcc acactgacga
    40201 gggtaaaatc ctttccgctc tcacgcaggg tgatatggga agcgagagag caggcacccg
    40261 gtttgtagaa caatttcatc ggtaactcct tttgtctgtg gtttaaagta tggtagtgcg
    40321 ttgctgaaca aaaaaaaagc cgctaacgaa aagttagcgg cttgtaaaag agtttccctg
    40381 aattttacgc tacagcagct ttcgccgctt tgtctgcagc gtcatcctgc gtcatacggt
    40441 gcagtttagg cgcggtcagc agcatcagta ctgcaataat ggcagtagcg acaccaatct
    40501 gcaagaatac gcgaccataa acttccagtg acatcagcgg gtcggtaacg ttatccggca
    40561 cagccatcat acccgcaaca taaccaccaa tcaggtttgc accggcagtg gtcaggaacc
    40621 agctacccat aatgaagccc atcagacgct gcggaacgag ttgtgcaacc attgccagac
    40681 ccagaccaga gatcatcagt tccccgatgc tctgcaggcc atagcttgcg accagccagc
    40741 ttacagacac gataccagcg tcagacgcga atttcgcacc cagcggcaga atcaggaacg
    40801 caccagaaca catcaccatg ccgattgcaa acttggttgg catcggcagg gtatcgccca
    40861 tcttgttata gatagcggcc agaatcggac taccgatgat gatccagaac gggttcagtg
    40921 cctgatactg ctcaggttct acggccagac ccagaatgga gtgctcaacg ttacgaatcg
    40981 caaagaagtt cagtgacgtt ggcatctggc tgtacagcac gaagaagata atggcttcga
    41041 gcatcaggat gaaggcaacg atcattttac gacgcgcagc acctttcatc gcgaaggctt
    41101 ctttaccgaa gataaccacg ataccgaagg caacaacgcc cagcgccata cgcgcaactt
    41161 cctgattgtg cagcagccag gtggcgatag cgatcagtgc cacaacacca ataatggtca
    41221 gcagcaggtt acggtagttg ataggctcga agtctggttt tgaaccgtac tgtttaaccc
    41281 agcgttggca gaaggcgaag ttaacgatag tgatcagcag gcctacaacg ctcaacgcaa
    41341 acgcaacact ccagccgtat ttcgcggcca gccacggcgt agcaatcata gagaagaaag
    41401 agccgatgtt gacggacatg tagtacatgg tgaatgcacc gtccagacgc gggtcgtttt
    41461 tctcatagca tgtagaaagc agagaagacg ggttagcttt aaacaggccg ttaccgaccg
    41521 caatagccgc catacccata taaacgatac cggcgtcgtg accagaccag gcaaccagag
    41581 cataaccaat cgccagcaca atagcgccga gcataattac gcgtttagta cccagtacct
    41641 tgtcacctaa ccagccgccg atagcgacca gaccataaac cagggcacta aaggaagaga
    41701 aaagggtgat tgaatccgct tcagacatac ccagttgttt aaccaggtaa acagccataa
    41761 ttccttgtag gccgtaataa ccaaaacgtt cccataactc aatcgagaag atgagataga
    41821 acgccttcgg ttgtttgaaa gcgttcaaac tgacgctttc agttggtttt tggtttgcag
    41881 tggacacttt tacctctttt tttacatccc atattaacgg gggtgctttc tcgcgttatg
    41941 tctaaaaaac atacgcgcaa ttgttatagt gggaggggaa acggcaggta atgttcacta
    42001 tcttgcactt tcagacaagt cctttgtaat aatctgttac atataactga ggcggggaat
    42061 tcaaccattc cgggaaatgt tatccagcgt taaatttttc aaaaaacgta acggcagatt
    42121 ttttcactgc actgagaggg gggtgatggc ttaacggcga tatgttctgc tatttagcgt
    42181 ttttactagt gagatagtcc agtttctgaa aaatagccag tgtaatgttt tgtaggtcaa
    42241 tatttgttgc gtgtgtaaat ttaaatgatt ttaacctgat tcttgcaatg tttttacatt
    42301 gcgacagcat cgtgatcttg atcacgaatg aatagaaaat ttcgctatta aaaaaacaat
    42361 taacctgcat ttttggttat ccgcaaacgg attacctgat gataacgcta agcaatggca
    42421 tcattcacgt taaaaagaag ttttaaaaga ggataaagaa aggttatcaa tggggtaatc
    42481 ggtgttaccc cttttcttca gatgtcaact ttctctttgt attcacaaag atcttcaata
    42541 atacaagagc cacagcgggg cttgcgggca atgcaggtat aacgcccgtg caggatcaac
    42601 caatggtggc agtcgacttt aaactctgcc ggaaccactt tcagtagctt ttcttctacc
    42661 tgttcgacgt ttttccccgg cgcaaattga gtacgattac aaacgcggaa aatgtgcgtg
    42721 tcgacagcaa tagtcggcca gccgaatgca gtgtttaata cgacgttggc tgttttacga
    42781 cctacgccgg gcagggcttc aagcgcagca cgatcttccg gaacctcgcc attatgctgc
    42841 tccagcaaga tacggcaggt tttgatgata ttttctgctt tgctgttata aagcccaatc
    42901 gttttgatat aggttttcac cccttcaacg cccagttcaa gcatcgctgc aggcgtattc
    42961 gccaccgggt agagtttcgc cgtcgcctta ttaacactga catcggtcgc ctgagcggaa
    43021 agcagtacgg caatcagcaa ttcaaaaggc gaactgaaat taagctcggt ggtgggatga
    43081 ggattgttct cacgcaggcg agtgaggatc tccaggcgtt ttgctttgtt catcagacat
    43141 tccctgtttc accgtttggc aatgcacgtt cggcagctgc ttcagtacgg cgctttttca
    43201 ttctttcatc aatcaggtat tttcctgcca gcatcagtcc caggccaata aatgcacctg
    43261 gaggcagcat cgccagcagg aaaggggagt cggtgtggaa aatttccacg cgtaatactt
    43321 ttgcccagct acctaacagc gcatctgcac cgtcaaacaa tgtgccattg ccgataattt
    43381 cgcgtagtga acccagcacg aacatggcgc aggttgcgcc cataccaatt gaaaagccgt
    43441 ccagtgccga aagcgccgga ccttttttgg cggcgaaggc ttcagcgcgg cccacaacga
    43501 tacagttagt gacaatcagc ggaataaaaa tccctaatga ttgatacagg ccaaaggcgt
    43561 aggcgttgat cagcatctgt acagcgctga ccaccgaggc gatgatcatc acgtaaatgg
    43621 gaatgcggat ctcggctggc gtccagtgac gcagcgtcga aatggtcagg ttggtcagcg
    43681 tcagtaccag cgtagtcgca agtcctaaac ccagagcgtt agtggcagtg gacgtgaccg
    43741 ccaacagagg acaaaggccg agcaactgga ccagcgcaga gttgtttttc cacaacccct
    43801 gaacaataac gtctttaatt tcgctcacgc tttattctcc acaggcagga agttgagaaa
    43861 gttgtgccgg taacgtctga gcgtacaatc cggcgcgttt taccgcatta accaccgcgc
    43921 ggggagtaat cgtcgcgccg gtgaactggt cgaaatcacc accatctttc ttcaccgccc
    43981 agtgcgcatc atctgcacca ctgatttttt tacccgcaaa atgggtgatc cagtcagaaa
    44041 ggcgcagttc gattttatcg ccaagccctg gcgtttcgtg gtgctctgtc acgcgcgtgc
    44101 caagtaccgt gccgttaaaa tcggctccca ccagcagctg aatcgcaccg gaatagccat
    44161 ctggcgcggt tgcttccaga acggcggcta ccggtttgtc atcctgtttg gcgatgtaaa
    44221 cccgatgctc acctttacct aactctggcg cagttaccag atagcaactc tgtgccagcg
    44281 cattgttata gcgttcggct ggcagcacct gatcaaataa tgccttttgt tgcagactgg
    44341 cctgttcagc aatcgtcgtt ttggtcatct ggttgatggc cgcagttaac cctgttgaac
    44401 ccgctgcaaa tagcgctaac gtaatgccgt gttttcggat agttttcagc atggtttacc
    44461 ctttgcgatg gccgtagacg cgcggacgcg tgtagtaatc gatcagagga accgtgatgt
    44521 tcgccagcag gacggcaaaa gccacgccgt caggatagcc gccgaaactg cggatcaacc
    44581 agactaataa gcccgcaagc gcgccgaaaa taagacgacc acgattggtc gtagaagcgg
    44641 taaccgggtc agtcaaaata aagaatgcgc cgagcatggt cgcaccagac agcagatgaa
    44701 tttgcggtgc tgccagtgtt tctggtgaga acaaccagcc caacgttgcg cataacgcca
    44761 gcgttactaa gaagctgagg ggaatatgcc agcgaatcgc tttctgccat agcaaccaca
    44821 ggccgccagc cagccaggcg agatttaccc attgccaacc agcgcccgcc agaataccgc
    44881 tgtagatcgg atattgcata atctgttcaa ccgaatgacc ggcacggaca gaggttttaa
    44941 atgtatccag cggtgtcgcc tgactaatgc catcaatacc taagcgtagt gtgttcatat
    45001 caccaccact ggcggtatgc ccgctgaaaa taacctgtat ggcgtcgata aaaccaggga
    45061 tgttgaccgc aatttcatgt ggcggtaacc agctggtcat ctgcaccggg aaggagatca
    45121 gtaagaccac ataaccaatc attgctggat taaacgggtt ttgccccaga ccgccataca
    45181 actgtttagc gatgatcacc gcaaacaccg tacccagcac gaccatccac catggcgcga
    45241 gggggggaat acttaccgcc agcaataagc ctgtcagcaa tgctgagtta tctttcaacg
    45301 ttgcggctac cgactgcttg cgtagtttga gtacgagagc ttcggctaac agagcactaa
    45361 ccgatgccaa caggatctga acgagagtac cccaaccaaa aaaccacagt tgcgctgcga
    45421 ttcctggcac ggctgcgagc aacaccaaca gcataatgcg cgatgtctgg cgctggttat
    45481 gggtataagg ggagctagct attctgaata ccatttagtc ctcgtttaca accttctgct
    45541 gggcggcttt tttggcctga gcgcgggcaa tagccgcggc aactgccgct ttgcgcggat
    45601 caacctgttc ttctggttct gcgttagtct gttgctgttc cagcttgcgc gctttggcac
    45661 gggcaatagc ggcttcgacg gcggctttgc gcggatcaac ctgttcttct ggttccgcat
    45721 tagcctgttg ctgttccagt ttgcgcgctt tggctcgggc aatagcggct tcgacggcgg
    45781 ct
//
LOCUS       DAZUDJ010000037        43423 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.037, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000037 DAZUDJ010000000
VERSION     DAZUDJ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43423
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.037"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            66..629
                     /gene="srlA"
                     /locus_tag="ACHY1N_002727"
                     /gene_synonym="gutA"
     CDS             66..629
                     /gene="srlA"
                     /locus_tag="ACHY1N_002727"
                     /gene_synonym="gutA"
                     /EC_number="2.7.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFS4045019.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQHRIERFAQRCAGNPVSRYLLLPCIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLNLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVHLAGATS"
     gene            626..1585
                     /gene="srlE"
                     /locus_tag="ACHY1N_002728"
                     /gene_synonym="gutE"
     CDS             626..1585
                     /gene="srlE"
                     /locus_tag="ACHY1N_002728"
                     /gene_synonym="gutE"
                     /EC_number="2.7.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFS4045020.1"
                     /translation="MTHIRIEKGTGGWGGPLELKATPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQY
                     IVEDIYVSGVKEENITVVGDATPQPSSVGRDYDTSKKITEQSDGLLAKVGMGMGSAVA
                     VLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGLVMLA
                     LICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACDFIPV
                     GLSLAEARQDTVRVGVPSVLVSRFLTGAPTVLIAWFVSGFIYQ"
     gene            1596..1967
                     /gene="srlB"
                     /locus_tag="ACHY1N_002729"
                     /gene_synonym="gutB"
     CDS             1596..1967
                     /gene="srlB"
                     /locus_tag="ACHY1N_002729"
                     /gene_synonym="gutB"
                     /EC_number="2.7.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFS4045021.1"
                     /translation="MTVIYQTTITRIGASATDALSDQMLITFREGAPADLEEYCFIHC
                     HGELKGELHPGLQFTLGQHRYPVTAVGSVAEDNLRELGHVTLRFDGLNEAEFPGTVHV
                     AGPVPDDIAPGSVLKFESVKE"
     gene            1971..2750
                     /gene="srlD"
                     /locus_tag="ACHY1N_002730"
     CDS             1971..2750
                     /gene="srlD"
                     /locus_tag="ACHY1N_002730"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HFS4045022.1"
                     /translation="MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQ
                     EINAEYGEGMAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            2855..3214
                     /gene="gutM"
                     /locus_tag="ACHY1N_002731"
     CDS             2855..3214
                     /gene="gutM"
                     /locus_tag="ACHY1N_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFS4045023.1"
                     /translation="MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGR
                     SSGRFKPRVVVAIALDDQQRIVDTLFMKGLTVFARPQKIPAITGMHAGDLQPDVIFPH
                     DPLSQNALSLALKLKRG"
     gene            3281..4054
                     /gene="srlR"
                     /locus_tag="ACHY1N_002732"
                     /gene_synonym="gutR"
     CDS             3281..4054
                     /gene="srlR"
                     /locus_tag="ACHY1N_002732"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HFS4045024.1"
                     /translation="MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     HAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIILDAGST
                     VLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNV
                     VCSLESVDKLITDAGIDPAFRQALEEKGIDVIITGESNE"
     gene            4047..5012
                     /gene="gutQ"
                     /locus_tag="ACHY1N_002733"
     CDS             4047..5012
                     /gene="gutQ"
                     /locus_tag="ACHY1N_002733"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HFS4045025.1"
                     /translation="MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGK
                     VVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALAASV
                     MDAMLELSRTGLGLVAVCDAQQQVQGVFTDGDLRRWLVGGGALTTPVNEAMTTGGTTL
                     QAQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(5009..6523)
                     /gene="norR"
                     /locus_tag="ACHY1N_002734"
     CDS             complement(5009..6523)
                     /gene="norR"
                     /locus_tag="ACHY1N_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311592.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HFS4045026.1"
                     /translation="MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALL
                     RYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
                     LLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETG
                     TGKELVAKAIHEASPRAVNPLIYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGAR
                     NLLQHYSFPGNVRELEHAIHRAVVLSRATRSGDEVILEAQHFAFPEVTLPPPEAAAVP
                     VVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD"
     gene            6710..8149
                     /gene="norV"
                     /locus_tag="ACHY1N_002735"
     CDS             6710..8149
                     /gene="norV"
                     /locus_tag="ACHY1N_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016966 - nitric oxide reductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HFS4045027.1"
                     /translation="MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEK
                     NVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYC
                     TANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDA
                     VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNL
                     PVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGI
                     AETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLR
                     FRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREI
                     ARQWALAPLPQSTVNTVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGT
                     PWSEVPDNFLCPECSLGKDVFEELASEAK"
     gene            8146..9279
                     /gene="norW"
                     /locus_tag="ACHY1N_002736"
     CDS             8146..9279
                     /gene="norW"
                     /locus_tag="ACHY1N_002736"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016731 - oxidoreductase activity, acting
                     on iron-sulfur proteins as donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HFS4045028.1"
                     /translation="MSNGIVIIGSGFAARQLVKNIRKQDATIPLTLIAADSMDEYNKP
                     DLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWVTDIDAEARVVKSQNNQWQYDK
                     LVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
                     CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILA
                     TLDRQRSIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAE
                     INGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLR
                     WQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM"
     gene            complement(9505..11757)
                     /gene="hypF"
                     /locus_tag="ACHY1N_002737"
     CDS             complement(9505..11757)
                     /gene="hypF"
                     /locus_tag="ACHY1N_002737"
                     /EC_number="6.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003998 - acylphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0016743 - carboxyl- or
                     carbamoyltransferase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HFS4045029.1"
                     /translation="MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD
                     GVEVRLLEDPETFLVQLHQHCPPLARIDSVEREPYIWSQLPTEFTIRQSTGGTMNTQI
                     VPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCP
                     ACDKEYRDPLDRRFHAQPVACPECGPHLEWVSHGEHAEQEAALQAAIAQLKMGNIVAI
                     KGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIV
                     LVDKKYVPELCDDIAPDLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISN
                     EQALADLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALVLPPGFKNVP
                     PVLCLGADLKNTFCLVRGEQAVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTPQYVV
                     HDVHPGYVSSQWASEMNMPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALPGGDLAATQPWRNLLAQCLRFVPEWQNYSE
                     TASVQQQNWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEA
                     LAASCHGVTHPVTMPLVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMRE
                     QATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAA
                     RWLAGEVQNG"
     gene            complement(11910..12437)
                     /gene="hydN"
                     /locus_tag="ACHY1N_002738"
     CDS             complement(11910..12437)
                     /gene="hydN"
                     /locus_tag="ACHY1N_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HFS4045030.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRTALMF"
     gene            complement(12586..13596)
                     /gene="ascG"
                     /locus_tag="ACHY1N_002739"
     CDS             complement(12586..13596)
                     /gene="ascG"
                     /locus_tag="ACHY1N_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator AscG"
                     /protein_id="HFS4045031.1"
                     /translation="MTTMLEVAKRAGVSKATVSRVLSGNGYVSQETKDRVFQAVEESG
                     YRPNLLARNLSAKSTQTLGLVVTNTLYHGIYFSELLFHAARMAEEKGRQLLLADGKHS
                     AEEERQAIQYLLDLRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRKNSSHSVW
                     CDHKQTSFNAVAELINAGHQEIAFLTGSMDSPTSIERLAGYKDALAQHGIALNEKLIA
                     NGKWTPASGAEGVETLLERGAKFSALVASNDDMAIGAMKALHERGVAVPEQVSVIGFD
                     DIAIAPYTVPALSSVKIPVTEMIQEIIGRLIFMLDGGDFSPPKTFSGKLIRRDSLIAL
                     SR"
     gene            13856..15313
                     /gene="ascF"
                     /locus_tag="ACHY1N_002740"
     CDS             13856..15313
                     /gene="ascF"
                     /locus_tag="ACHY1N_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose/arbutin/salicin transporter
                     subunit IIBC"
                     /protein_id="HFS4045032.1"
                     /translation="MAKNYAALARSVIAALGGVDNISAVTHCMTRLRFVIKDDQLIDS
                     PTLKTIPGVLGVVRSDNQCQVIIGNTVSQAFQEVVSLLPGDMQPAQPVGKPKLTLRRI
                     GAGILDALISTMSPLIPAIIGGSMVKLLAMILEMSGVLTKGSPTLTILNVIGDGAFFF
                     LPLMVAASAAIKFKTNMSLAIAIAGVLVHPSFIELMAKAAQGEHVEFALIPVTAVKYT
                     YTVIPALVMTWCLSYIERWVDRITPAVTKNFLKPMLIVLIAAPLAILLIGPIGIWIGS
                     AISALVYTIHGYLGWLSVAIMGALWPLLVMTGMHRVFTPTIIQTIAETGKEGMVMPSE
                     IGANLSLGGSSLAVAWKTKNPELRQTALAAAASAIMAGISEPALYGVAIRLKRPLIAS
                     LISGFICGAVAGMAGLASHSMAAPGLFTSVQFFDPANPMSIVWVFAVMALAVVLSFIL
                     TLLLGFEDIPVEEATAEARKHQSVQPTVAKEVSLN"
     gene            15322..16746
                     /gene="ascB"
                     /locus_tag="ACHY1N_002741"
     CDS             15322..16746
                     /gene="ascB"
                     /locus_tag="ACHY1N_002741"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase AscB"
                     /protein_id="HFS4045033.1"
                     /translation="MSVFPEGFLWGGALAANQSEGAFREGGKGLTTVDMIPHGEHRMA
                     VKLGLEKRFQLRDDEFYPSHEATDFYHRYKEDIALMAEMGFKVFRTSIAWSRLFPQGD
                     KITPNQQGIAFYRSVFEECKKYGIEPLVTLCHFDVPMHLVTEYGSWRNRKLVEFFSRY
                     ARTCFEAFDGLVKYWLTFNEINIMLHSPFSGAGLVFEEGENQDQVKYQAAHHQLVASA
                     LATKIAHEVNPQNQVGCMLAGGNFYPYSCKPEDVWAALEKDRENLFFIDVQARGAYPA
                     YSARVFREKGVTINKAPGDDEILKNTVDFVSFSYYASRCASAEMNANNSSAANVVKSL
                     RNPYLQVSDWGWGIDPLGLRITMNMMYDRYQKPLFLVENGLGAKDELAANGEINDDYR
                     ISYLREHIRAMGEAIADGIPLMGYTTWGCIDLVSASTGEMSKRYGFVYVDRDDAGNGT
                     LTRTRKKSFWWYKKVIASNGEDLE"
     gene            complement(16860..17279)
                     /locus_tag="ACHY1N_002742"
     CDS             complement(16860..17279)
                     /locus_tag="ACHY1N_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4045034.1"
                     /translation="MTANAARAVKATRELVNAVPFLGGSDSEDDYREALELVEYLIEE
                     DDTNPLIDFLASRIAEYENNNEKFAEFDKAVAAMPVGVALLRTLIDQHNLTYADLKNE
                     IGSKSLVSQILSGQRSLTISHIKALSARFGVKPEWFL"
     gene            complement(17350..18104)
                     /locus_tag="ACHY1N_002743"
                     /pseudo
     CDS             complement(17350..18104)
                     /locus_tag="ACHY1N_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001374644.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18147..18617)
                     /gene="hycI"
                     /locus_tag="ACHY1N_002744"
     CDS             complement(18147..18617)
                     /gene="hycI"
                     /locus_tag="ACHY1N_002744"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HFS4045035.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPE
                     NDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDQLK
                     EDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEEE"
     gene            complement(18610..19020)
                     /gene="hycH"
                     /locus_tag="ACHY1N_002745"
     CDS             complement(18610..19020)
                     /gene="hycH"
                     /locus_tag="ACHY1N_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase assembly protein HycH"
                     /protein_id="HFS4045036.1"
                     /translation="MSEKVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDEYLAWIATLEAGSEARRKMEGVPKYGEIVIDINHVPMLANAFDKARAA
                     QTSQQKEWSTMLLSMLHDIHQENAIYLMVRRLRD"
     gene            complement(19017..19784)
                     /gene="hycG"
                     /locus_tag="ACHY1N_002746"
     CDS             complement(19017..19784)
                     /gene="hycG"
                     /locus_tag="ACHY1N_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HFS4045037.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARGPGEQDEQPAEILHGDMVQPLRVKVDREARRLAGYRYGRQIADDFLTQ
                     LGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEARIR"
     gene            complement(19784..20326)
                     /gene="hycF"
                     /locus_tag="ACHY1N_002747"
     CDS             complement(19784..20326)
                     /gene="hycF"
                     /locus_tag="ACHY1N_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HFS4045038.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCA
                     ACVNACPSNALTVETDLATGELAWEFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR
                     QKCLVPSDRIELTRHMKEAI"
     gene            complement(20336..22045)
                     /gene="hycE"
                     /locus_tag="ACHY1N_002748"
     CDS             complement(20336..22045)
                     /gene="hycE"
                     /locus_tag="ACHY1N_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycE"
                     /protein_id="HFS4045039.1"
                     /translation="MSEEKLGQHYLAALNEAFPGVVLDHAWQTKDQLTVTVKVNYLPE
                     VVEFLYYKQGGWLSVLFGNDERKLNGHYAVYYVLSMEKGTKCWVTVRVEVDANKPEYP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKDDMIQTRQLAQQMRREVQELVDVLLSTPNMEQRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTALNMIDYGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            complement(22063..22986)
                     /gene="hycD"
                     /locus_tag="ACHY1N_002749"
     CDS             complement(22063..22986)
                     /gene="hycD"
                     /locus_tag="ACHY1N_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycD"
                     /protein_id="HFS4045040.1"
                     /translation="MSVLYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIIKLLGRQSVGPDASGWVFRLTPYVMVGVMLTIATALPVVTVGSPLPQLGDLITLLY
                     LFAIARFFFAISGLDTGSPFTAIGASREAMLGVLVEPMLLLGLWVAAQVAGSTNISNI
                     TDTVYHWPLSQSIPLVLALCACAFATFIEMGKLPFDLAEAEQELQEGPLSEYSGSGFG
                     VMKWGISLKQLVVLQMFVGVFIPWGQMETFTAGGLLLALVIAIVKLVVGVLVIALFEN
                     SMARLRLDITPRITWAGFGFAFLAFVSLLAA"
     gene            complement(22989..24815)
                     /gene="hycC"
                     /locus_tag="ACHY1N_002750"
     CDS             complement(22989..24815)
                     /gene="hycC"
                     /locus_tag="ACHY1N_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HFS4045041.1"
                     /translation="MSAISLINSGVAWFIAAAVLAFLFSFQKTLSGWIAGIGGAVGSL
                     YTAAAGFTVLTGAVGVSGALSLVSYDVQISPLNAIWLITLGLCGLFVSLYNIDWHRHA
                     QVKCNGLQINMLMAAAVCAVIASNLGMFVVMAEVMALCAVFLTSNSKEGKLWFALGRL
                     GTLLLAIACWLLWQRYGTLDLRLLDMRMQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGILTLSLLGGNAPLWWGIALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALEQPALIALGLVGGLYHLLNHSL
                     FKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLSNSGAFVARLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ATCAPLLMSVSVVALAICCVIGGVAAPWLLPMLSAAVPLPLEPANTTVSQPMITLLLI
                     ACPLLPFIIMAICKGDRLPSRSRGAAWVCGYDHEKSMVITAHGFAMPVKQAFAPVLKL
                     RKWLNPVSLVPGWQCEGSALLFRRMALVELAVLVVIIVSRGA"
     gene            complement(24812..25423)
                     /gene="hycB"
                     /locus_tag="ACHY1N_002751"
     CDS             complement(24812..25423)
                     /gene="hycB"
                     /locus_tag="ACHY1N_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycB"
                     /protein_id="HFS4045042.1"
                     /translation="MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEK
                     ESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLDIPANANTPKAPPAPPAPARISTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK"
     gene            complement(25548..26009)
                     /gene="hycA"
                     /locus_tag="ACHY1N_002752"
     CDS             complement(25548..26009)
                     /gene="hycA"
                     /locus_tag="ACHY1N_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HFS4045043.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYYVETKDGEDKQRIAQAQLSIDGM
                     IDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPAA"
     gene            26221..26571
                     /gene="hypA"
                     /locus_tag="ACHY1N_002753"
     CDS             26221..26571
                     /gene="hypA"
                     /locus_tag="ACHY1N_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008901 - ferredoxin hydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HFS4045044.1"
                     /translation="MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSL
                     AFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVA
                     DDGLQIRRIEIDQE"
     gene            26575..27447
                     /gene="hypB"
                     /locus_tag="ACHY1N_002754"
     CDS             26575..27447
                     /gene="hypB"
                     /locus_tag="ACHY1N_002754"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0051604 - protein maturation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HFS4045045.1"
                     /translation="MCTTCGCGEGNLYIEGDEHNPHSAFRSAPFAPAARPKMKITGIK
                     APEFTPSQTEEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     KQLVLNLVSSPGSGKTTLLTETLMRLKDSVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDNGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIACAREVNPEIEIILISATSGEG
                     MDQWLNWLETQRCA"
     gene            27438..27710
                     /gene="hypC"
                     /locus_tag="ACHY1N_002755"
     CDS             27438..27710
                     /gene="hypC"
                     /locus_tag="ACHY1N_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HFS4045046.1"
                     /translation="MCIGVPGQIRTIDGNQAKVDVCGIQRDVDLTLVGSCDENGQPRV
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEEK"
     gene            27710..28831
                     /gene="hypD"
                     /locus_tag="ACHY1N_002756"
     CDS             27710..28831
                     /gene="hypD"
                     /locus_tag="ACHY1N_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HFS4045047.1"
                     /translation="MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
                     AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPH
                     QCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA"
     gene            28828..29838
                     /gene="hypE"
                     /locus_tag="ACHY1N_002757"
     CDS             28828..29838
                     /gene="hypE"
                     /locus_tag="ACHY1N_002757"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation carbamoyl dehydratase
                     HypE"
                     /protein_id="HFS4045048.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLELA
                     QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKAVVTSMAETARTAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWG
                     AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKA
                     LRDATRGGVNAVVHEFAAACGCGIEISEAALPVKPAVRGVCELLGLDALNFANEGKLV
                     IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            29912..31990
                     /gene="flhA"
                     /locus_tag="ACHY1N_002758"
     CDS             29912..31990
                     /gene="flhA"
                     /locus_tag="ACHY1N_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HFS4045049.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLCEALSQLVKRSALA
                     DNAAIVLWQAQTQRASYYASREKDTPIKYEDETVLAHGPVRRILSRPDTLHCSYEEFC
                     ETWPQLVAGGLYPKFGHYCLMPLAAEGHIFGGCEFIRYDDRPWSEKEFNRLQTFTQIV
                     SVVTEQIQSRVVNNVDYELLCRERDNFRILVAITNAVLSRLDMDELVSEVAKEIHYYF
                     DIDDISIVLRSHRKNKLNIYSTHYLDKQHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     HERDDLAPYERMLFDTWGNQIQTLCLLPLMSGDTMLGVLKLAQCEEKVFTTTNLNLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVL
                     KQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KIIQTDVRLIAATNRDLKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAF
                     TFKIARRLGRNIDSIPAETLRTLSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDI
                     ALPEPETPPAATVVAQEGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMK
                     RLGIDKSALI"
     gene            complement(32027..32380)
                     /gene="ygbA"
                     /locus_tag="ACHY1N_002759"
     CDS             complement(32027..32380)
                     /gene="ygbA"
                     /locus_tag="ACHY1N_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HFS4045050.1"
                     /translation="MSGKRISREKLTIKKMIDLYQAKCPQASAEPEHYEALFVYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPILTVRHLIDDKRP
                     VPELPEKYRPKKTRE"
     gene            complement(32412..32591)
                     /locus_tag="ACHY1N_002760"
     CDS             complement(32412..32591)
                     /locus_tag="ACHY1N_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001363568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045051.1"
                     /translation="MIPELIISGEEANGEFLMLVPGKMLFCSFCVMLMKQVRKIASVG
                     EPFFFRVIVPFKIKM"
     gene            32667..35228
                     /gene="mutS"
                     /locus_tag="ACHY1N_002761"
     CDS             32667..35228
                     /gene="mutS"
                     /locus_tag="ACHY1N_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFS4045052.1"
                     /translation="MSAIENFDAHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDA
                     KRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATS
                     KGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEP
                     ADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFG
                     TRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRN
                     LEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDF
                     TAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQA
                     LREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERL
                     EVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKE
                     YEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLN
                     YTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYM
                     RQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILH
                     NATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKME
                     GVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELES
                     ISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            35334..35990
                     /gene="pphB"
                     /locus_tag="ACHY1N_002762"
     CDS             35334..35990
                     /gene="pphB"
                     /locus_tag="ACHY1N_002762"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HFS4045053.1"
                     /translation="MPSTRYQKINAHHYRHIWVVGDIHGEYQLLQSRLHQLSFFPETD
                     LLISVGDNIDRGPESLDVLRLLNQPWFISVKGNHEAMALDAFATGDGNMWLASGGDWF
                     FDLNDSEQKEATDLLLKFHHLPHIIEITNDNIKYVIAHADYPGSEYLFGKEIAESELL
                     WPVDRVQKSLNGELQQINGADYFIFGHMMFDNIQTFANQIYIDTGSPKSGRLSFYKIR
                     "
     gene            complement(36041..36808)
                     /gene="ygbI"
                     /locus_tag="ACHY1N_002763"
     CDS             complement(36041..36808)
                     /gene="ygbI"
                     /locus_tag="ACHY1N_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor YgbI"
                     /protein_id="HFS4045054.1"
                     /translation="MIPVERRQIILEMVAEKGIVSIAELTDRMNVSHMTIRRDLQKLE
                     QQGAVVLVSGGVQSPGRVAHEPSHQVKTALAMTQKAAIGKLAASLVQPGSCIYLDAGT
                     TTLAIAQHLIHMESLTVVTNDFVIANYLLDNSNCTIIHTGGAVCRENRSCVGEAAATM
                     LRSLMIDQAFISASSWSVRGISTPAEDKVTVKRAIASASRQRVLVCDATKYGQVATWL
                     ALPLSEFDQIITDDGLPESASRALAKQDLSLLVAKNE"
     gene            37004..37912
                     /gene="ltnD"
                     /locus_tag="ACHY1N_002764"
     CDS             37004..37912
                     /gene="ltnD"
                     /locus_tag="ACHY1N_002764"
                     /EC_number="1.1.1.411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonate dehydrogenase"
                     /protein_id="HFS4045055.1"
                     /translation="MKTGSEFHVGIVGLGSMGMGAALSCVRAGLSTWGADLNSNACAT
                     LKEAGACGVSDNAATFAEKLDALLVLVVNAAQVKQVLFGETGVAQHLKPGTAVMVSST
                     IASADAQEIATALAGFDLEMLDAPVSGGAVKAANGEMTVMASGSDIAFERLAPVLEAV
                     AGKVYRIGAEPGLGSTVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTNAAG
                     NSWMFENRMRHVVDGDYTPHSAVDIFVKDLGLVADTAKALHFPLPLASTALNMFTSAS
                     NAGYGKEDDSAVIKIFSGITLPGAKS"
     gene            37909..39171
                     /gene="otnK"
                     /locus_tag="ACHY1N_002765"
     CDS             37909..39171
                     /gene="otnK"
                     /locus_tag="ACHY1N_002765"
                     /EC_number="2.7.1.217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxo-tetronate kinase"
                     /protein_id="HFS4045056.1"
                     /translation="MIKIGVIADDFTGATDIASFLVENGLPTVQINGVPTGKMPEAID
                     ALVISLKTRSCPVVEATQQSLAALSWLQQQGCKQIYFKYCSTFDSTAKGNIGPVTDAL
                     MDALDTPFTVFSPALPVNGRTVYQGYLFVMNQLLAESGMRHHPVNPMTDSYLPRLVEA
                     QSTGRCGVVSAHVFEQGVDAVRQELARLQQEGYRYAVLDALTEHHLEIQGEALRDAPL
                     VTGGSGLAIGLARQWTQENGNQARKAGHPLAGRGVVLSGSCSQMTNRQVAHYRQIAPA
                     REVDVARCLSTETLATYAHELAEWVLGQESVLAPLVFATASTDALAAIQQQYGAQKAS
                     QAVETLFSQLAARLAAEGVARFIVAGGETSGVVTQSLGIKGFHIGPTISPGVPWVNAL
                     DKPVSLALKSGNFGDEAFFSRAQREFLS"
     gene            39168..39806
                     /gene="ygbL"
                     /locus_tag="ACHY1N_002766"
     CDS             39168..39806
                     /gene="ygbL"
                     /locus_tag="ACHY1N_002766"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HFS4045057.1"
                     /translation="MSDFAKVEQSLREEMTRIASSFFQRGYATGSAGNLSLLLPDGNL
                     LATPTGSCLGNLDPQRLSKVAADGEWLSGDKPSKEVLFHLALYRNNPRCKAVVHLHST
                     WSTALSCLQGLDSSNVIRPFTPYVVMRMGNVPLVPYYRPGDKRIAQDLAELAADNQAF
                     LLANHGPVVCGESLQEAANNMEELEETAKLIFILGDRPIRYLTAGEIAELRS"
     gene            39811..40587
                     /gene="ygbM"
                     /locus_tag="ACHY1N_002767"
     CDS             39811..40587
                     /gene="ygbM"
                     /locus_tag="ACHY1N_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HFS4045058.1"
                     /translation="MPRFAANLSMMFTEVPFIERFAAARKAGFDAVEFLFPYDYSTLQ
                     IQKQLEQNHLTLALFNTAPGDINAGEWGLSALPGREHEAHADIDLALEYALALNCEQV
                     HVMAGVVPAGEDAERYRAVFIDNLRYAADRFAPHGKRILVEALSPGVKPHYLFSSQYQ
                     ALAIVEEVARDNVFIQLDTFHAQKVDGNLTHLIRDYAGKYAHVQIAGLPDRHEPDDGE
                     INYPWLFRLFDEVGYQGWIGCEYKPRGLTEEGLGWFDAWR"
     gene            40676..42040
                     /gene="ygbN"
                     /locus_tag="ACHY1N_002768"
     CDS             40676..42040
                     /gene="ygbN"
                     /locus_tag="ACHY1N_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family transporter"
                     /protein_id="HFS4045059.1"
                     /translation="MSTITLLCIALAGVIMLLLLVIKAKVQPFVALLLVSLLVALAAG
                     IPAGEVGKVMIAGMGGVLGSVTIIIGLGAMLGRMIEHSGGAESLANYFSRKLGDKRTI
                     AALTLAAFFLGIPVFFDVGFIILAPIIYGFAKVAKISPLKFGLPVAGIMLTVHVAVPP
                     HPGPVAAAGLLHADIGWLTIIGIAISIPVGIVGYFAAKIINTRQYAMSVEVLEQMQLA
                     PASEEGATKLSDKINPPGVALVTSLIVIPIAIIMAGTVSATLMPPSHPLLGTLQLIGS
                     PMVALMIALVLAFWLLALRRGWSLQHTSDIMGSALPTAAVVILVTGAGGVFGKVLVES
                     GVGKALANMLQMIDLPLLPAAFIISLALRASQGSATVAILTTGGLLSEAVMGLNPIQC
                     VLVTLAACFGGLGASHINDSGFWIVTKYLGLSVADGLKTWTVLTTILGFTGFLITWCV
                     WAVI"
     gene            complement(42079..42333)
                     /locus_tag="ACHY1N_002769"
     CDS             complement(42079..42333)
                     /locus_tag="ACHY1N_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-oxidative hydroxyarylic acid decarboxylases
                     subunit D"
                     /protein_id="HFS4045060.1"
                     /translation="MICPRCADEQIEVMAKSPVKDVWTVYQCQHCLYTWRDTEPLRDT
                     EPLRRTSREHYPEAFRMTQKDIDDAPMVPSIPPLLVEGKR"
     gene            complement(42344..>43423)
                     /locus_tag="ACHY1N_002770"
     CDS             complement(42344..>43423)
                     /locus_tag="ACHY1N_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFS4045061.1"
                     /translation="DGEEINLFDILPLFRLNDGDGGFYLDKACVVSRDPLDPDNFGKQ
                     NVGIYRMEVKGKRKLGLQPVPMHDIALHLHKAEERGEDLPIAITLGNDPIITLMGATP
                     LKYDQSEYEMAGALRESPYPIATAPLTGFDVPWGSEVILEGVIESRKREIEGPFGEFT
                     GHYSGGRNMTVVRIDKVSYRTRPIFESLYLGMPWTEIDYLMGPATCVPLYQQLKAEFP
                     EVQAVNAMYTHGLLAIISTKKRYGGFARAVGLRAMTTPHGLGYVKMVIMVDEDVDPFN
                     LPQVMWALSSKVNPAGDLVQLPNMSVLELDPGSSPAGITDKLIIDATTPVAPDNRGHY
                     SQPVVDLPETKAWAEKLTAMLAARK"
BASE COUNT        10172 a        11821 c        11539 g         9891 t
ORIGIN      
        1 ctttcaatct gattagatta ggttgccgtt tggtaataaa acaataaatc ctgaaggaga
       61 gaacaatgat agaaaccatt actcatggtg cagagtggtt tatcgggctg ttccaaaagg
      121 gcggagaggt gtttaccggg atggtgaccg gcattcttcc gctgttgatt agcctgctgg
      181 ttatcatgaa cgcactgatt aattttatcg gtcagcatcg tattgaacgt tttgctcaac
      241 gttgcgccgg taaccctgtt tcccgttacc tactgttacc gtgcattggc acgtttgtct
      301 tttgcaatcc gatgacccta agcctgggtc gctttatgcc ggaaaagtac aaacccagct
      361 actacgcggc ggcctcttat agctgccact caatgaatgg cctcttcccc catatcaacc
      421 ctggcgaact gtttgtttat cttggcattg ccagcggtct gacaacgctg aacctgccac
      481 ttggcccact ggcggtgagt tatctgctgg ttggtctggt caccaatttc ttccgcggct
      541 gggtgaccga tctgaccacc gccatttttg agaaaaagat gggcattcaa cttgaacaaa
      601 aagttcacct ggcaggagca acatcatgac gcatattcgg atcgaaaaag gaacgggtgg
      661 ctggggcggc ccgcttgagc tgaaagccac gccgggaaaa aaaatcgtct atatcaccgc
      721 cggtacccgg cctgcgattg ttgacaaact ggcacagctt actggctggc aggctattga
      781 cggatttaaa gaaggtgaac ccgcggaggc ggaaattggt gtcgcggtaa tcgactgtgg
      841 cggcacatta cgctgcggca tctatccgaa acgacgtatt cccaccatta atatccactc
      901 gacgggcaag tccggtccgc tggcgcagta cattgtggaa gatatttatg tctctggcgt
      961 aaaagaagaa aacatcactg tagtgggtga tgcgacacca caaccctctt ccgtgggccg
     1021 tgactatgac accagtaaga aaatcaccga acaaagcgat ggtttactgg cgaaggtggg
     1081 aatgggcatg gggtccgccg ttgcggtgct gtttcaatct ggtcgtgaca ccatcgacac
     1141 tgtattaaaa accattctgc cgtttatggc attcgtctcg gcgctcattg gcatcattat
     1201 ggcttctggc cttggtgact ggattgccca cggtcttgct ccgctggcga gccatccact
     1261 gggtctggtc atgctggcgc tcatctgctc cttcccactg ctttcacctt tcctcggccc
     1321 aggcgcagtt atcgcacagg ttatcggcgt attgattggc gtgcagattg gtctcggcaa
     1381 tattccgccg catctggctt taccggcact gtttgccatc aacgcgcagg cggcctgcga
     1441 cttcatcccg gtcggtttgt cgctggcgga agctcgtcag gacacggttc gcgtcggtgt
     1501 cccttctgta ctggtgagcc gctttttaac cggcgcgccg actgtactga tcgcctggtt
     1561 tgtctccggt tttatctatc aatagaggct gaaacatgac cgttatttat cagaccacca
     1621 tcacccgtat cggcgcgagt gccactgacg ccctcagcga ccagatgctc atcacctttc
     1681 gtgaaggcgc gccagcggac ctcgaagagt attgcttcat tcattgccac ggcgagttga
     1741 aaggtgaact ccatcctggt ttgcaattta cgctcgggca gcatcgctat ccggtgaccg
     1801 ccgttggcag cgtggcggaa gacaaccttc gcgaactggg tcatgtcacc ctgcgcttcg
     1861 atggtttaaa cgaagcggaa tttccgggca ctgtccatgt ggcaggccct gtacccgacg
     1921 atatcgcgcc gggatcggtt ttgaagtttg aatctgttaa ggagtaaaaa atgaatcagg
     1981 ttgccgttgt catcggtggt gggcaaacct taggcgcgtt cctgtgccac ggtctggctg
     2041 ccgaggggta tcgcgtcgcg gttgtcgata ttcagagcga caaagccgca aatgtggcac
     2101 aagaaattaa cgccgaatat ggtgaaggta tggcgtacgg ttttggtgct gacgccacca
     2161 gcgagcaaag cgttctggcg ctctctcgtg gggtagatga aatctttggt cgcgtggatt
     2221 tgctggtcta tagcgccgga atagcaaaag cagcctttat cagcgacttc cagctcggcg
     2281 attttgaccg ttcgctacaa gtgaatctgg tgggttattt cctgtgtgcc cgtgaatttt
     2341 cgcgtttgat gatccgcgac gggattcagg gtcgcattat tcagatcaac tcgaaatccg
     2401 gcaaagtggg tagcaaacac aactctggct acagcgcagc gaaatttggt ggcgtcgggc
     2461 tgactcaatc actggcgctg gatctggcgg agtacggcat tacggtgcat tcactgatgc
     2521 tcggtaacct gctgaaatcg ccgatgttcc agtcactgtt gccacaatac gcgaccaagc
     2581 tgggtatcaa accggatcaa gtcgagcagt attacatcga caaagtaccg ctcaaacgcg
     2641 gctgcgatta tcaagatgtg ctgaatatgc tgctgttcta cgccagtcct aaggcgtcgt
     2701 actgcaccgg acagtcgatc aatgtcaccg gcggtcaggt gatgttctga tcaacagcgg
     2761 agatccgtta aggatctccg tgagactata gaatgcctga tgcgctacgc tcatcaggca
     2821 tacaggactt ccgccactac attaaggaaa agttatggta tccgcactca tcaccgtcgc
     2881 cgttatcgcc tggtgtgcgc aactggcctt aggcggctgg caaatttctc gttttaaccg
     2941 tgccttcgac acactatgcc agcaagggcg ggtcggcgtg ggccgttcca gcgggcgctt
     3001 taaaccgcgg gtcgtggtcg ccatcgccct ggacgatcag cagcgcatcg tcgacacctt
     3061 gtttatgaaa ggactgaccg tcttcgcccg accgcaaaaa attcccgcaa ttaccggtat
     3121 gcatgcgggt gatttacagc ccgatgtgat ctttccccat gatccactat cacagaatgc
     3181 tctatcattg gcgcttaaac tgaaacgtgg ataatttcgt tgtgaatgtt acttgcttgc
     3241 gaagttatca ttttgaaacc taaatcaggt aatcacgccc atgaaacctc gtcagcgtca
     3301 ggccgccatt ctggagtatc tgcaaaagca gggtaaatgc tcggttgaag aattggcgca
     3361 atactttgac accacaggca caaccattcg caaagatctg gtcattctgg aacatgccgg
     3421 aaccgtcatt cgtacttatg gcggagtggt gttgaataaa gaggaatccg atccgcctat
     3481 cgatcataaa acgctcatca acacccacaa gaaagagctg attgcagaag ctgccgttag
     3541 ttttattcat gatggcgact caataattct tgatgctggc agtaccgttt tgcagatggt
     3601 ccccctgctc tcgcgcttta ataacatcac ggtgatgacc aacagtctgc atatcgtcaa
     3661 tgcgctatct gaactggata acgaacaaac catcctgatg ccaggcggaa catttcgcaa
     3721 aaaatcggcc tcatttcacg ggcaactggc agagaatgcc ttcgagcatt tcaccttcga
     3781 caaattattc atgggtactg acggcatcga tctcaatgcg ggcgtaacca ccttcaacga
     3841 ggtctatacc gtcagtaagg caatgtgcaa tgccgcgcgc gaagtgattt taatggcgga
     3901 ctcatcaaag tttggccgta aaagccccaa cgtagtttgc agtcttgaaa gcgtcgataa
     3961 gctgattacc gacgcaggta tcgatccggc gtttcgtcag gcgctggaag agaaagggat
     4021 cgatgtgatc ataaccggag agagcaatga gtgaagcact actgaacgcg ggacgtcaga
     4081 cgttaatgct ggagttgcag gaagcaagcc gtttaccgga acgtctgggc gatgattttg
     4141 ttcgcgccgc caatatcatc ctgcactgcg aaggcaaagt ggtggtttcg ggaattggca
     4201 aatcgggcca cattggtaag aaaatcgccg caacacttgc cagtaccggc acaccggctt
     4261 tttttgtcca tccggcagaa gcactgcacg gcgatctggg gatgattgaa agccgcgatg
     4321 tgatgctgtt tatctcttac tccggtggcg cgaaggaact ggatctgatt attccgcgtc
     4381 tggaagataa atctatcgcg ctgctggcga tgaccggcaa accgacgtca ccgctgggcc
     4441 tggcggcaaa agcggtgctg gatatctccg tagaacgcga agcctgcccg atgcaccttg
     4501 cgccgacctc cagcaccgtc aataccctga tgatgggtga cgcgctggcg atggcggtca
     4561 tgcaggcgcg cggttttaat gaagaagatt ttgcccgctc ccacccagct ggggcactgg
     4621 gcgctcgctt gctgaataaa gtgcatcatc tgatgcgccg tgatgacgct atcccgcagg
     4681 tagcgttagc cgccagcgtg atggatgcga tgctggagct cagccgcacc ggtctggggc
     4741 tggtggcggt atgtgacgct caacaacagg tacaaggcgt ctttaccgac ggcgatttac
     4801 gtcgctggct ggttggcggc ggcgcactca ccacgccagt taatgaagcg atgacgacag
     4861 gcggcaccac attacaggcg caaagccgtg ccatcgacgc caaagagatc ctgatgaagc
     4921 gcaaaatcac tgccgcaccg gtggtagatg aaaacggcaa actcaccggc gcaattaact
     4981 tgcaggattt ctatcaggcc gggattattt aatccttcaa tcccagacgt ttcgccagcc
     5041 gatgcaggtt ggcgacgtca gtttccagca ttcgcgcgca ggcagcccag ttgtgatgat
     5101 tttgtgccag tgcctggcga atggtttcac gctggaacgc ttctgtcgct tcacgcagat
     5161 tttgcttaac aacgggcacc gctgccgctt ctggcggcgg caacgtcacc tcaggaaaag
     5221 caaaatgttg cgcctcaaga atcacttcat cgccgctgcg agtggctctc gacagtacta
     5281 ccgcccgatg aatagcatgt tccagttcgc gcacgttccc cggaaaactg tagtgttgca
     5341 gtaaatttcg cgccccggca cttaatacca cgcgggagag ccccagccgc aaacgacact
     5401 gctcgcagaa ataccccgcc agcagaatga catcatcgcc ccgctcacgc agcggcggca
     5461 ccgaaagtgg aaacacgctc aggcgatgaa acaagtcagc gcgaaatcgc cctgccagta
     5521 cctcttcgcg taagtcgcgg ttagtcgccg ccagcacgcg cacatcgacc cgcaaactgc
     5581 ggtcatcgcc aacgcgctga atatcgccat actgcaacac tcgcagcaac ttggcctgca
     5641 aagccaacga caactcgccg atctcatcga gaaacagtgt gccgttatcc gccatttcaa
     5701 acttcccgct gcggttactg atagcgccag taaacgcccc tttcacatgc ccgaacagtt
     5761 cactttccgc cacactttcc ggcagtgcgg cacagttgag atagatcagc ggattcaccg
     5821 cccgtggcga ggcttcatga atcgctttcg ccaccagctc cttaccggtt cccgtctcac
     5881 cgctgattaa gacgttgaga tcggacgccg ccacaatctc aatctctttt ttcaattgcg
     5941 tcatgcctgg cgataagcca atcatctgcg tctgtttcac cgcttcaaac ggcgcggcat
     6001 cgcccggcag catattctgg ctttccagtt gctcaatcag caacgcattg cttaacgctc
     6061 ccgccgccag cgcagcaatc agccgtaact cttcatcgct gaaaacatcg aactgatcgg
     6121 gctgcatccc gtcgagcgtc aatgcgccaa tcaggttttg cccggcaaac aatggcagac
     6181 caacgcaggc gtgaaccttc agactctcct gcccaggaat caaaccgtca tagggatcgg
     6241 gcaattcgct gtctgcagga aagcgcacca cgtccccggc gcgggcaatc gcttcaagcc
     6301 gtggatgccc ttccagcgca aagcgtctac cgagtacatc ctttgccaga ccgtcgatgg
     6361 caagcggaat aaactgccgc gaatcgtaac gtagcaacgc agacgcatcg cactccagca
     6421 cctgacgtag cgtggtgatc aggcgctgaa aacgatcctg atgaccaatc ccacgctgca
     6481 attcgatggc gatattcgcc agcacatcaa cggaaaaact catctttgcc tcactgtcaa
     6541 tttgactata gatattgtca tatcgaccat ttgattgata gtcattttga ctactcatta
     6601 atgagcatac ttttatttat atagtaaaaa caatcagata aaaaactggc acacaatctg
     6661 caattagcaa gacatctttt tagaacacgc tgaataaatt gaggttgcta tgtctattgt
     6721 ggtgaaaaat aacattcatt gggttggtca acgtgactgg gaagtgcgtg attttcacgg
     6781 cacggaatat aaaacgctgc gcggcagcag ttacaacagc tacctcatcc gcgaagaaaa
     6841 aaacgtgctg atcgacaccg tcgaccataa attcagccgc gaatttgtgc agaacctgcg
     6901 taatgaaatc gatctggcgg atatcgatta catcgtgatt aaccatgcag aagaggacca
     6961 cgctggggcg ctgaccgaac tgatggcgca aattcccgat acgccgatct actgtactgc
     7021 caacgctatc gactcgataa atggtcatca ccatcatccg gagtggaatt ttaatgtggt
     7081 gaaaactggc gacacgctgg atatcggcaa cggcaaacag ctcatttttg tcgaaacacc
     7141 aatgctgcac tggccggaca gcatgatgac ttacctgaca ggcgacgcgg tgctgttcag
     7201 taacgatgct ttcggtcagc actactgcga cgagcatctg ttcaacgatg aagtggatca
     7261 gacggagctt ttcgagcagt gccagcgtta ctacgccaat atcctgacgc cgttcagccg
     7321 cctggtaacg ccgaaaatta ccgagatcct gggctttaac ttaccagtcg atatgatagc
     7381 gacctcccac ggcgtggtct ggcgcgataa cccgacgcaa attgtcgagc tgtacctgaa
     7441 gtgggccgct gattatcagg aagacagaat caccattttc tacgacacca tgtcgaataa
     7501 cacccgcatg atggctgacg ctatcgccca gggaattgcg gaaactgacc cacgcgtggc
     7561 ggtgaaaatt ttcaacgtcg cccgaagcga taaaaacgaa atcctgacca atgtcttccg
     7621 ctcaaaaggc gtgctggtcg gcacttcgac gatgaataac gtgatgatgc cgaaaatcgc
     7681 cgggctggtg gaggagatga ctggtttacg cttccgtaac aaacgcgcca gtgctttcgg
     7741 ctctcacggc tggagcggcg gtgcggtgga tcgtctttcc acgcgcctgc aggatgcggg
     7801 tttcgaaatg tcgcttagcc tgaaagccaa atggcgacca gaccaggacg ctctggagtt
     7861 atgtcgtgaa cacggtcgcg aaatcgcccg tcagtgggcg ctcgcgccgc tgccgcagag
     7921 cacggtgaat acggtggtta aagaagaaac ctctgccacc acgacggctg acctcggccc
     7981 acggatgcag tgcagcgtct gccagtggat ttacgatccg gcaaaaggcg agccaatgca
     8041 ggacgttgcg ccaggaacgc cgtggagtga agttccggat aacttcctct gcccggaatg
     8101 ctccctcggc aaagacgtct ttgaagaact ggcatcggag gcaaaatgag taacggcatt
     8161 gtgatcattg gttcgggctt cgccgcccgc caactggtga aaaatattcg caaacaggac
     8221 gccactattc cattaaccct gattgccgcc gacagcatgg atgagtacaa caaacctgac
     8281 ctcagccatg ttatcagtca ggggcaacgt gccgacgacc ttacccgcca gacggcgggt
     8341 gaatttgccg agcagtttaa tctgcgcctg tttccgcaca cctgggtgac ggatatcgat
     8401 gccgaagccc gtgtggtgaa aagccagaat aatcagtggc aatacgacaa gctagtgctg
     8461 gcaaccggtg ccagcgcctt tgtcccgcca gtgcctgggc gtgagttaat gctgacgtta
     8521 aatagtcagc aagagtatcg cgcctgtgaa acgcaactgc gggatgcccg acgcgtgttg
     8581 attgtcggtg gtggcttgat tggtagcgaa ctggcgatgg atttttgtcg tgcaggcaaa
     8641 gcggtcacgc taatcgacaa cgctgccagt attctggcgt cattaatgcc accggaagta
     8701 agcagccgct tgcagcatcg gttgacggag atgggcgttc atctgttgtt gaaatctcag
     8761 ttgcaggggc tggaaaaaac agattctggc attctggcaa cgctggaccg ccagcgcagt
     8821 atcgaagtgg atgcggtaat tgccgccacc ggactgcgcc cggaaaccgc cctggcacga
     8881 cgcgccgggc tgacgattaa tcgcggcgtt tgcgtcgata gttatctgca aaccagtaat
     8941 gccgatattt acgcgctggg cgattgcgcg gaaattaacg gtcaggtatt gccgttcctc
     9001 cagccgattc aacttagcgc gatggtgctg gcaaaaaatc ttctcggcaa taacacgcca
     9061 ctgaaactac cggcaatgct ggtgaaaatc aaaacgccgg aattaccgct gcatctggca
     9121 ggcgaaaccc agcgtcagga tttacgctgg cagattaata ccgaacgcca gggaatggtg
     9181 gcgcgcggcg ttgacgatgc tgaccagctt cgcgcctttg tggtcagtga ggatcggatg
     9241 aaagaggcat ttggattgtt gaaaacgttg ccgatgtagg tgggctactg tgcctaaaat
     9301 gtcggatgcg acgctggcgc gtcttatcca acctacgggg agcgcatgtg ttggtcacat
     9361 actgcgttca tgtcgcatcc acctactgtg cccaaaatgt cggatgcgac gctggcgcgt
     9421 cttatccgac ctacggggac gcatgtgtag gccggataag gcgtttacgc cgcatccggc
     9481 aatggtgtcc aaatgcaaca cgttttatcc gttctggact tcacccgcta accaacgcgc
     9541 cgcagcaata accccctgcc ccagagacaa accgccatca cccgccggta aactctgtgg
     9601 aaagagcaat gtgaaatcag cgagataatg cgccagacgt gcacgcagca aacggttatg
     9661 aataaccccg ccgctaaata ccagcgtagt gataccacgc atcgtggcct gctcacgcat
     9721 caacgcggca aaaccctgcg ccagcgcatc atgaaacgcc cacgcgcgtt gattaaccgg
     9781 tgcctgccag ttcagccact gctgccagaa agtggcgaga tccagttgat tgtccaccag
     9841 cggcattgtc accggatgcg tcactccgtg gcacgaagct gcgagtgcct ccagagcaca
     9901 agccgcttca ccttcataac ttaacgtggc tggcgcacag cccagtgccg ccgccacggc
     9961 atcgaacaac cgcccacacg atgacgccag cggcgcgtta attccacgct caatggcccg
    10021 cgccagcacg ctccagtttt gctgttgcac acttgctgtt tcagaataat tctgccactc
    10081 cggcacaaag cgcaggcact gcgccagcag gtttcgccac ggctgcgtcg ccgccaaatc
    10141 gccacccgga agcgccactg caggcaagcc gcccaggtgc tcacattcgc gatagttcac
    10201 ccgcagacac tcgccgcccc acaaagcgcc gttctccccc ataccgatac catcgagcgt
    10261 caaagcaatg acatcaccgc catccagcgg ccactgatgc tctgccagac acgccgctgc
    10321 gtgggcatga tgatgcagca ccgtttgcgt cggcatattc atttcgctcg cccactggct
    10381 ggagacatag cccggatgca cgtcatgcac aacgtattgc ggagtgaaat cgtagatgtt
    10441 ttgcatcagg cgtaacgctt cgcgccactg catctggatg ccatcgtcac ttaaatcgcc
    10501 cagatgctga ctcaacaccg cttgttcacc gcgcaccagg cagaaggtgt ttttcagatc
    10561 cgcgccaaga cacagcacag gcggaacatt tttaaagccc ggaggcaaaa ccagcgcatc
    10621 cggcacatac ccgcgtgaac ggcgcagcat ttcgccgctt tcgcgcacca ccgaatcatc
    10681 catccgctgc acgatgtcgc ggttatgtat caagaatccg tcggcaatgc cctgcaaatc
    10741 cgccagcgcc tgttcgttgc tgatagctgg tggtttaccg ctcaggttgc cggaggtcat
    10801 caccagcggg cattgcagtt cctgtaacag caaatgctgg agcgggttcg caggcaacat
    10861 taccccgact tcgttaaggt caggggcgat atcatcacaa agctcaggaa cgtatttttt
    10921 atccaccagc acaatcggcg cggcgggcgt ggtaagcaac tggcgcgcag cgtctggtaa
    10981 accgtcagcc actggcaaca tgaccgccag cggtttcgcc gggcgatgtt tgcgcgcccg
    11041 cagtgtcgcc accgcgttac tgttacgtgc atcgcaggca agatgaaatc cgccaatccc
    11101 tttgatggcg acaatgttgc ccatttttaa ctgtgcgata gccgcctgta atgccgcctc
    11161 ttgttctgca tgttcaccat gacttaccca ttcaagatgt gggccacact ccgggcaggc
    11221 caccggctgg gcgtggaagc gacgatcgag cgggtcgcgg tactctttgt cacaagccgg
    11281 acacaacgga aacgccgcca tcacggtaaa cgggcggtcg taaggcatgg cgcgaataat
    11341 ggtgaaacgc gggccgcagt gggtacagtt gataaacgga taacgataac gccgttcgcc
    11401 tggggtattc atttcggcaa gacaggcagg gcaagtagcg gcatcgggaa caatttgcgt
    11461 attcatggtg ccgcctgtgc tctggcgtat agtgaactcg gtgggcagtt gtgaccagat
    11521 gtacggctca cgctcgacgc tatcaatacg cgccagcggc gggcagtgct gatgcaattg
    11581 aacaagaaac gtttccgggt cttccagcag ccggacttct acgccatcgc cgtcattaca
    11641 gacatcgccg tgaagattta attgctgtgc cagctgccag acaaacggac gaaaaccgac
    11701 gccctgcact ttgcctcgaa tacgcagttg gacaccgcaa gatgtgtttt ttgccattga
    11761 gttattcccg ccatcatgaa ttgcgtaacc cgccctgccg gacacgactg cgtcgtatcc
    11821 ggcagtctca ggtcggcgat accgccagct ccgtattcta cgaatatttc cgggaattcc
    11881 tttgatgcca gaacagttct ataagatttt tagaacatca gcgccgtacg gcgacgtttt
    11941 tctgcgctca gttgttcaag tttattacga tcgacacaaa tcagcgcatg ggtcgggcaa
    12001 gccgccatac acgccgggcc gtcttcgcga tggttgcaca ggtcgcattt attggcttca
    12061 gctttgtcag cccgtacatt cagccccgcg ccgctgttgc ggatcaccgg acgtaccacc
    12121 acttccatcg cgccatacgg gcaagccacc acgcaggttt tgcaaccaat gcaacgttcc
    12181 tgcatcacat gaacaaaccc tttatcacgg ctgatagcac cattcgggca gacgttagcg
    12241 cacggtgcat cttcacactg acggcagact gtcgccgtgg aaatgttcac acctttaatg
    12301 acatggattc gcggtaaaaa ggtttccggg gtcagcgatg cacagtcctg attttcctga
    12361 tgagaaacca cgcacgccac ttcacaggta cggcaaccaa tacatttact cgcgtcagca
    12421 atgatgaaac ggttcatcaa attctccagc aatgacagtt aatgcgccga tacattcaca
    12481 aatcatgcca gtttttaatt tgctgttatt taaggaaatt aatttctgta atgcaggaaa
    12541 aaagatgtca tcgacactag tgacgatgac atgtgatgac aatgtttatc gcgaaagggc
    12601 aatgagtgag tcgcggcgga tcagttttcc gctgaaggtt ttcggcggtg agaaatcccc
    12661 gccatcgagc ataaaaatca gccgtccaat aatttcctga atcatctctg ttaccggaat
    12721 ttttacgctg gagagcgccg gaacggtgta gggggcaatt gcgatatcat cgaatccgat
    12781 aactgacacc tgctctggca ccgctacgcc gcgctcgtgc aacgctttca tcgcacctat
    12841 cgccatatcg tcgttactgg caactaacgc gctaaattta gccccacgtt cgagcaacgt
    12901 ttctacccct tcggccccgc tggcgggcgt ccatttaccg ttagcgataa gtttttcatt
    12961 gagcgcaata ccatgctgcg ccagcgcgtc tttataccca gcaagacgtt caatgctggt
    13021 gggggaatcc atcgagccgg taaggaaagc aatctcctga tgtccggcgt ttatcaactc
    13081 tgccacggca ttaaagctgg tctgtttatg atcgcaccag acgctatggc tgctgttttt
    13141 gcgcaggcgg cgattaagca ccattatcgg ctgactgtgc gcgtcaatga tgtcatcgat
    13201 ctcatccacg cttaaaaaac gcgggtaaat cataatggcg tcgcagcgca aatccagcag
    13261 atactgaatc gcctggcgct cttcttcggc gctgtgttta ccatctgcca atagcaactg
    13321 ccgccctttc tcttccgcca ttcgcgcggc atgaaagagt aattcactaa aataaatgcc
    13381 gtggtaaagc gtgttggtca ctaccagccc cagcgtctga gtactcttcg ccgacagatt
    13441 gcgcgccagc aagtttgggc ggtaaccgct ctcttctacc gcctgaaaca cgcgatcttt
    13501 agtctcctgg ctgacgtagc cattacctga aagcacgcgg gaaacggtcg cttttgaaac
    13561 cccggcgcgc ttcgccactt ccagcatcgt cgtcatcatt ttcatccctt tacacgcaat
    13621 caacgcagtg tactgcaccg tttgccgatt gtccttgcgc aatcggcggg aaaaatattc
    13681 aggtgaccgg tttcacaaat ataaaaaatg aacaattaac tctcttgctt atttagtgac
    13741 aactattcat gattttgtga aaccggtttc ctaattccgt ttcagcatcg gcatttttcc
    13801 gttacgtcga ctgataacaa ctacatctac cctactgata acaggataaa atccgatggc
    13861 caaaaattat gcggcgctgg cacgctcggt gatagcggca ctgggcggcg ttgataacat
    13921 ctcggcagtc acgcactgta tgacgcgttt gcgctttgtt atcaaagatg accagcttat
    13981 cgacagcccg acgttaaaaa ccatccccgg cgtgctcggc gtggtacgta gtgacaacca
    14041 gtgtcaggtg attatcggca ataccgtttc acaagccttt caggaagtcg tcagcctgct
    14101 gccgggagat atgcagcccg cacagcccgt gggtaaaccc aaactcacgc tgcgtcgcat
    14161 tggtgcgggg atcctcgatg cgctgatcag caccatgtca ccgctgatcc cggcgattat
    14221 cggcggatcg atggtcaaac tgctggcgat gatcctcgag atgagcggcg tgttgacaaa
    14281 aggatcgccg accttaacca ttctgaatgt gattggtgac ggtgctttct tcttcctgcc
    14341 gctaatggtc gcggcttcgg ccgccatcaa atttaaaacc aatatgtcgc tggcgattgc
    14401 catcgcaggt gtgctggtac atccgagctt tattgaactg atggcgaaag cggcccaggg
    14461 tgaacatgtc gaatttgccc tgattccggt caccgcggtg aaatatacct acacggtgat
    14521 cccggcgctg gtgatgacct ggtgcctgtc atatatcgaa cgctgggtgg atcgcattac
    14581 accggctgtg accaaaaact tcctcaagcc aatgctgatt gtgttgattg ccgcaccgct
    14641 ggcaatcctg ctgattggcc cgattggtat ctggatcggt agcgccattt cggcgctggt
    14701 ttacaccatt catggttatc tgggctggct ttcagtcgcc attatgggcg cgctgtggcc
    14761 tctgctggta atgaccggga tgcaccgcgt ctttacgcca accatcattc agaccattgc
    14821 cgaaaccggc aaagaaggga tggtcatgcc gtcagagatc ggcgctaacc tgtcgctggg
    14881 cggttcatca ctggcggtgg cgtggaaaac gaaaaacccg gaactgcgcc agacggcgct
    14941 ggctgcggcg gcatcagcca ttatggcggg gatttccgaa ccggcgttat acggcgtggc
    15001 gatccgcctg aaacgtccgc ttatcgccag tcttatcagc ggttttattt gcggcgcggt
    15061 tgccggtatg gcggggcttg ccagccactc aatggcagcg ccggggctat ttaccagcgt
    15121 gcagttcttc gatccggcga atccaatgag catcgtctgg gtattcgcgg tcatggcgct
    15181 ggcggtggtg ctgtcgttta tcctcacact gttgctcggc tttgaggata ttcctgttga
    15241 ggaagcgact gccgaggcgc gaaagcatca gagcgtacaa ccgaccgtcg ccaaagaagt
    15301 aagtcttaat tgaggatgaa aatgtcagta tttccagaag gttttttatg gggcggcgcg
    15361 cttgccgcca accagtctga aggtgcgttc cgtgaaggtg gcaaagggct gaccactgtc
    15421 gatatgatcc cacacggcga gcatcgaatg gcggtgaaac tggggctgga aaaacgtttt
    15481 cagttgcgcg atgacgagtt ttatcccagc catgaggcga cggattttta tcatcgttat
    15541 aaagaagata tcgccctgat ggcagagatg ggattcaagg ttttccgtac ctcaattgcc
    15601 tggagccgcc tctttccgca gggcgataaa atcacgccca atcagcaggg cattgctttt
    15661 taccgttctg tctttgaaga gtgtaaaaag tacggtatcg aaccgctggt cacgttgtgc
    15721 cacttcgatg tgccgatgca tctggtcacc gaatatggct cctggcgtaa ccgcaagctg
    15781 gtggagtttt tcagccgcta cgccagaacc tgctttgaag catttgatgg tctggtgaaa
    15841 tactggctaa ccttcaatga aatcaacatt atgttgcata gcccgttctc cggcgcgggt
    15901 ctggtgtttg aagaaggtga aaatcaggat caggtgaaat atcaggccgc gcatcaccag
    15961 ctggttgcca gtgcgctagc caccaaaatc gcccatgagg ttaacccgca aaatcaggtg
    16021 ggctgtatgc tggcgggcgg taacttctac ccttacagct gcaaaccgga agatgtctgg
    16081 gcggcgctgg agaaagatcg ggaaaacctg ttttttatcg atgtgcaggc gcgcggcgcg
    16141 tatccggctt actctgcccg cgtatttcgc gaaaaagggg taaccatcaa caaagcaccg
    16201 ggcgatgatg aaatcctgaa aaacaccgtc gattttgtct ctttcagcta ttacgcctcg
    16261 cgctgcgcct cggcggagat gaacgccaac aacagcagtg cggcgaacgt ggtgaaatcg
    16321 ctgcgtaatc cgtatctaca ggtgagcgac tggggctggg gaattgatcc actcggtctg
    16381 cgtatcacca tgaatatgat gtacgatcgt tatcagaagc cgctgtttct ggtggaaaac
    16441 ggcctcggcg caaaagatga acttgctgcc aatggcgaga ttaacgatga ctatcgcatc
    16501 agctatttac gcgaacatat ccgcgcaatg ggcgaagcga ttgcagatgg cattccgctg
    16561 atgggctaca ccacctgggg ctgtattgat ttagtttccg cctctacggg tgaaatgagc
    16621 aaacgctacg gttttgtcta cgtagaccgt gacgacgcag gcaacggcac gctgacgcgc
    16681 acgcgtaaga aatcgttctg gtggtataaa aaagtaattg ccagtaatgg ggaagattta
    16741 gagtaagtaa ccgtgccgga tgcggcgtga acgccttatc cggcctacat gtcgcacgaa
    16801 ccatgaaggc ccgataagcg cagcgcatcg ggcaatctgg ggtttggcat cagtcaaaat
    16861 caaagaaacc attccggctt aacgccaaat cgggctgaaa gtgccttaat gtgggatatc
    16921 gtcagggatc gttgtccaga caaaatctga ctgaccaggg atttagagcc gatttcgttc
    16981 ttcaaatccg cataggtcag attatgttga tcaatcaacg tgcgaagtaa cgccacgcca
    17041 accggcattg ccgcaacggc tttgtcgaac tctgcaaact tttcgttgtt gttttcatac
    17101 tctgcaatgc ggctcgccag aaagtcgata agtggattgg tgtcatcttc ttcaatcaaa
    17161 tattcgacca gttccagtgc ttcacgataa tcatcttctg agtcactgcc tcccagaaag
    17221 gggactgcat tgaccagttc tcttgttgct ttaacagcgc gtgcagcatt agcagtcatt
    17281 ctttgttctc tctgtagtaa cgtgacgtct gtctgcacgt aatccccctc atagccactc
    17341 tgcaaaaagt cagttctggt tcaccccata aagcacatcc ccctttatca agcaacgctg
    17401 cgtctgcgcc agatcttccg tttgcgggtc gcgcccggcg atgggtttga ggacgagttt
    17461 acggttgggg gtataagtaa aacgcgtgag cgcgggatag cttaacttgc caaaccagcc
    17521 gtgaacacgc tgccatttgg cgtcttttac cgatacagac tggttatcca gtaaccggaa
    17581 tcaaactgca tatccagcaa ttgcgtgtgg ccattccttt gtaaatccag caaatcatca
    17641 atgccagttt cacttgcggt ataaaaacca tcggactgaa aaacacacgg gcgaccttgc
    17701 tgattaaagg tcatcagaat caaaaacgcg ttaggtgcca gaccatttcc tgaaataccc
    17761 cgccagataa ccagatcctg aatgccgtta cgatcaagat cggcacggta aagttgcgca
    17821 ttacccgcca tattttgcag cactcccaca ggcacagacc aggatttacc ggcgcgatct
    17881 ttaccgttca attgccattc actatcatca tttggcatct tttcaagcgt cacgccagca
    17941 acgccgactt ttctaaaatg ccagttttgc tcggcatcat aaggcatggt caggagaggt
    18001 ttcagcgccc gcttttgcgc gtattcgctg tcactcattg gcagatattc ggtaaagctg
    18061 gtggcctgtg caggcagcac taagctcaat aaaaaagcgc acatccctgt tctgatgttc
    18121 aattccctga attccctgat ggagaattat tcttcttcca ccgctaactg cgcaaatcca
    18181 ccatttcctt cccagccttc cagtcgttga taaacggttt ctaccgcatc tttaatcggc
    18241 tgggtcatcg ggtagtaaaa gccgacgata tccggctgaa tgccgaggaa aatcacttca
    18301 ccaatgtctt cttttaactg gtcgataagg taattcaacg gcatgttatg ggtagtcatc
    18361 ataaacatct cggcgatatc atccgggtcg atgatgcgga tttcgccggg gtttagcccc
    18421 atatccgtgg cgtcgacaat cagcagtcgt gtcgggcgca gttcacggat ggcgacgatg
    18481 tcgttttccg gtgcactacc gccgtcaatc accacccagt tacctttcgg cgcggcggcg
    18541 cacttttccg ccagcagcgg gccagcgcca tcatcgccca tcatgctatt gccaacacag
    18601 agtaaaacgt cagtcacgca gtctcctcac catcaaatag atggcgtttt cctgatgaat
    18661 atcatgcagc atacttaaca gcattgtact ccattccttc tgctgcgaag tttgcgctgc
    18721 ccgggcttta tcgaatgcgt tggccagcat cggcacatgg ttaatgtcga tgacgatctc
    18781 gccatatttc ggtacgcctt ccattttgcg gcgggcttcg ctgcccgcct ccagagtggc
    18841 aatccatgcc agatattcat cccatgggca ggtgagcgcc gcttccaggc aatcgataac
    18901 cccaaggtgg tgaccaatcg ccaggctgta atagaccacc tgctgcgcct cggcgggcgt
    18961 ggcatcgttc tcatcaataa atttacggct cagttgactg aacaccacct tttcactcat
    19021 cggatacgcg cctcttcaac aacatgattc agatggctga caatctcgtt cagacgcgga
    19081 tcgttttccg cttccagcca gcgtgcaacc tgttcttcgc cctgccctaa ctgtgtcagg
    19141 aagtcatcgg caatctgacg accgtaacga taacctgcca ggcggcgtgc ttcgcgatcc
    19201 actttcacac gcagcggctg caccatatcg ccatgcagga tttccgccgg ttgttcatcc
    19261 tgctcacccg ggccacgggc gtgaattttc tgctccagca ggccgagcgc cattgcaaag
    19321 ccgtacagcg tggcggcagg cgttggcggg caaccaggga tgtagacatc taccgggacg
    19381 attttatccg taccgcccca cacgcagtag agatcgtgga agatcccgcc actgttaccg
    19441 caggcaccgt aggagataca gattttcggg tccggcgcgg actgccacgc acgcagcgca
    19501 ggggatcgca ttgcacgggt gaccgcgccg gtaaacagta aaatatccgc atgacgcggt
    19561 gaaggaacga ctttaatgcc gaagcgttct gcatcaaaca gcggcgaaag cgtggcgaaa
    19621 atttcgattt cgcagccgtt gcagccgccg cagtccacgc ggtaaacgta ggcagaacgt
    19681 ttgatttttt tcagtaacga cgccttcatg ctggcgatgg attcatccac cgtcatcggg
    19741 accggaatgc cgttggcgtc acgggggcct aataaattgc tcatcagatg gcctctttca
    19801 tatggcgagt cagttcaata cggtcggacg gcaccaggca tttctggcgc ttacattccg
    19861 ggcaagtctc aaagctttcg cggtggtttt ccgcgcggct gtcgccgttg tgcttaagta
    19921 gcgcaatggc gtagtcgatc tctttctgga cagcgaaagg acgattgcag acgcgacagt
    19981 tgcacagcgc gaagcgggac tgttgcagga agtcttcttt cttccacacc gccagttcgt
    20041 actcttgcga cagtttgatc gccgccgtcg ggcaaacttc ttcgcagcgt ccacagaaga
    20101 tgcagcgtcc aagattgaac tcccacgcaa gctctcctgt ggcgaggtcg gtttcaaccg
    20161 ttaaggcgtt tgacgggcag gcattgacgc aggccgcgca gccgatgcac tgctgcgggt
    20221 tctgctctgg cttaccacgg aagtttttat caaccgcaat cggctccagc ggataagacg
    20281 aggtcgccgt gccggttttg ataacttttt tgataaaggt aaacatggcg attccttatt
    20341 tcagcggcga gtttttacgc tcaatgctgt agcgctcgag ttctttgtac ggcaccactt
    20401 tgctcttctt cttacgtaca tcgaccaccg tcatgcggtc ggtacaggag tagcaagggt
    20461 ccaggctacc gataatcagc ggcgcatcgg aaacggtatt gccacgcagc atgtagcgca
    20521 gggtcggcca gttcgcgtag gtcgcggcac ggcagcgcca gcggtacagc ttctggttgt
    20581 cgccggtcat gctccagtgg atatcgtcgc cgcgcggcgc ttcggcaaag cccagcgcga
    20641 aacggtgcgg aatgtaggta aagccttcca ccatcagcgg accgcccggc aggttatcca
    20701 gaccgtagtc gatcatgttc agcgcggtat aaacttcgtt gatacgcact ttcagacggg
    20761 aaataacgtc gcagccctgc tcgctgtgga cttccattgg cagcaggcca taaccgacaa
    20821 acgggtgatc ggcgcgagta tcgcgggcgt gaccgctggc gcgaaccatc gggccaacgt
    20881 tactgaaatc gcgggcgatt tccgggtcca gacgaccaat gccgacggtg cgctgttcca
    20941 tgttcggcgt actcagcagc acatccacca gctcctgcac ttcacgacgc atctgttgcg
    21001 ccagctggcg ggtctggatc atgtcatctt tcaacagatc gcgacgaatc ccgccgatca
    21061 ggttcaggcc gtaggtttta cgcgcaccgg tgaggatctc tgccattttc atggaggttt
    21121 cacgcacgcg gaagaactgc ataaagccgg agtcaaagcc ggtaaagtgg caggcgagac
    21181 cgaggttgag cagatgcgag tgcaggcgtt ccacctccag cagaatggcg cggatcatct
    21241 gcgcacgttc tggcacctga atacccatcg cgttttctac cgacgtggtg taggcagtgc
    21301 tgtgggcaaa gccgcagatc ccgcacacac ggtcagagag gaaggtcact tcgttgtaac
    21361 ccatacgggt ttccgccagt ttttccatgc cgcgatgaac gtagaacaga cggtagtcgg
    21421 cgtcgataat gttttcgcca tcgacgaaca gacggaagtg gcccggttcg tcagaagtga
    21481 cgtgcagcgg accaatcggc acgacgttgt ttttcttgtc gcccagttcg ttgatgaact
    21541 cgtaggtttc agcatcggta gtcggtgccg gacgctgacg ataatccatg ctgtctttac
    21601 gcagcggata aagttcatcc ggccagtcat ccggcagcac cagacgacgt tcatccggca
    21661 gaccaaccgg aatcaaaccg tacatatcgc gcacttcgcg ctcgccccac accgccgccg
    21721 gaacgcgcgg cgtcacggac ggatactccg gtttgttggc gtcaacttcg acgcgaaccg
    21781 ttacccaaca cttggtgccc ttctccatcg acagcacgta ataaacggcg taatgaccat
    21841 tcagtttgcg ttcgtcgtta ccaaacagca ccgacagcca gccaccctgc ttgtagtaga
    21901 gaaactccac cacttccggc aggtagttca ccttcacggt cacggtcagc tgatctttgg
    21961 tctgccaggc gtggtccagc acgacgcccg gaaatgcctc attcagcgcg gcgagataat
    22021 gttgacctaa tttttcttca gacatgctca aactctcttt aatcacgccg ccagcaagga
    22081 gacgaacgct aaaaatgcaa agccaaaccc agcccaggta atgcgcggag taatatcaag
    22141 acgcagacgg gccatgctgt tttcgaacag cgcgataacc aggacgccga cgaccagttt
    22201 gacgatggca atcaccagcg ccagcagcag cccaccggcg gtgaaggttt ccatctgtcc
    22261 ccacgggata aatacgccga cgaacatctg cagcaccacc agctgtttca ggctgatacc
    22321 ccatttcatg acgccaaagc cgctgccgct gtattcagag agcgggcctt cctgcagctc
    22381 ctgctcggct tccgccaggt cgaacggcag tttgcccatt tcgataaagg tggcgaacgc
    22441 acaggcacaa agcgccagta ccagcgggat gctctggctc agcggccagt gataaacggt
    22501 gtcggtgatg ttgctgatgt tggtggaacc ggcaacctgt gcggcaaccc acagaccaag
    22561 cagcagcatc ggttcgacca gcacgccaag catcgcttca cggctcgcgc cgatagcggt
    22621 aaacgggcta ccggtatcca gaccagaaat ggcaaagaag aaacgcgcga tggcaaagag
    22681 atacagtaag gtgattaaat cacccagttg cggcagcgga gaaccgacgg tcaccaccgg
    22741 cagcgcagta gcgatagtca gcatgacgcc caccatcaca tacggcgtca ggcggaacac
    22801 ccagccggag gcatccgggc caacgctctg gcggcccagc agtttgataa tgtcacgata
    22861 ctcctgcaac acacccggcc cacgacggtt atgtaagcgg gctcgcgcca cgcgggtaat
    22921 accggagagc agcggcgcaa cggcaaatag caccagcgcc tgaattaacg gatataaaac
    22981 actcattctc aggctcctcg tgaaacaata atcaccacca gcaccgccag ttcaaccagc
    23041 gccatccggc ggaacagcaa cgcactcccc tcgcactgcc agcccggcac cagagacacc
    23101 ggattcagcc atttgcgtag tttcagcacc ggcgcaaacg cctgtttcac cggcatggca
    23161 aaaccgtgag cggtaatcac cattgatttt tcgtggtcgt agccgcacac ccaggccgca
    23221 ccgcgggaac gcgacggcaa acgatcgcct ttgcaaatcg ccataatgat gaatggcagc
    23281 agcgggcagg caatcagcag caacgtgatc atcggttgag aaacggtggt gttagcaggc
    23341 tccagcggca gaggtacagc agcagagagc atcggcagca gccacggcgc agcaacaccg
    23401 ccaattacgc agcaaatcgc cagtgccact acgcttacgc tcatcaggag cggcgcacag
    23461 gtggcgtttt cggcttcttt ggtacgcggc gcgccgagga acgtgacgcc atagactttc
    23521 gccatacaca tcaccgccag cgcaccggta attgccagac ccacagcgag cagcggcccc
    23581 agcagacggg caacaaacgc gccactattg ctcagtttga aaaaggattg atagataacc
    23641 cattccccgg caaacccgtt cagcggcggc agcgcagcca ttgccatcaa cccgactaac
    23701 atggcgatgg agataaccgg cattttcttg ccaataccac cgagtttttc gatatcgcga
    23761 tgaccggtac ggaaccagac gctccccgcc ccgaggaaca gtacgctttt gaacaggcta
    23821 tggttaagca gatggtacag accaccgacc agaccaaggg caatcagcgc cggttgttcg
    23881 agcgcgatac ccgttacgcc agcgcccagc cccagcagga taatgccgat attttccagg
    23941 gtgtggtaag ccagcaggcg ctggatgttg tgttccatca acgcatacag accaccgacg
    24001 aacgcggtga tcatgccgag caccagcagc gcgatccccc accacagcgg cgcgttacca
    24061 cccagcagcg acagggttaa aatgcccagc aggccaattt tcatgactac cgtagaaaac
    24121 aacgcggcag ctggcgcaga ggcgttagca tgtgcctgcg gcacccagcc gtgcagcgga
    24181 ataatcccgg ccagcaggcc aaagccaatc acaccgagca gccagatatc ggaaccgagc
    24241 ggcagctgtt gcatacgcat atccagcagg cgcagatcca gcgtgccata acgctgccac
    24301 agcagccagc aagcaatcgc cagcagcaga gtgccaagac gccccagcgc aaaccacagt
    24361 ttgccctctt tgctgttgct ggtgaggaac accgcacaca aggccatgac ttcggccatt
    24421 accacgaaca tgccgaggtt gctggcaatg acggcgcaga cggcggcagc catcaacata
    24481 ttgatctgca agccgttgca cttcacctgc gcgtggcgat gccagtcaat gttatagagg
    24541 ctgacaaaca gaccgcaaag gccgagggta atcagccaaa tcgcgttaag cggggagatt
    24601 tgcacatcgt agcttaccag cgacagcgca ccgctcacgc caaccgcgcc agtcagcaca
    24661 gtgaagcccg cggctgccgt atacaggcta ccaaccgcgc cgccaattcc ggctatccag
    24721 ccacttagcg tcttttgaaa agaaaagaga aatgccagaa cagcggcggc aataaaccac
    24781 gccacgccgc tattgatcag ggaaattgcg ctcatttagc ctctccactt tgagcctgct
    24841 gaaacaaggt gagatcgcca aagtccgtat taaaagtcag ctcacgctta cgtttgctga
    24901 cgcgggcgat atcggtgtta tccaccagat gcagggcttt ggtcgggcac atccgcacgc
    24961 aggccggacc ttgttcatca aaactgcaaa ggtcacattt gacggcgatc gcgcgaatac
    25021 ccggcaccca gtcaagcagc gtactgatac gcgccggagc aggcggtgcc ggtggcgctt
    25081 tcggggtatt ggcatttgca ggaatatcca gcggacggct gccggaaaat tcaattgcgc
    25141 caaacgggca ggcgatgccg cacagcttgc agcttacgca caggctttca ttcaactgca
    25201 cggccccatc aacgcgggtg atggcgttaa ccgggcagac caccgcgcag ggtgcatctt
    25261 cacagtggtg acagagctgc ggcgcagatt ctttttcatt tagcatcact ctcaggcgcg
    25321 gcattgattg caggccgtgc tggcgatgcg tctctgaaca ggcggcctca caagtgtggc
    25381 agccgataca gagcgtggag tcagcaatta caaaacgatt caccaggcat tcctcaggtg
    25441 attgtcattt ttgacgaaaa catgccgatg aaatgtcatt ttcgacactc atcgacacgc
    25501 ccatccccaa acaggcgtaa cgcctgcaaa acgggcaaag cctcagctca tgctgccggg
    25561 ctttgtccct ttaccagttg gcttaaattc accggcacat tgttttcaat ggcggtgtat
    25621 aagctgtcgt aaacgccagc gattttttcg agatagtgtt ccagaacctg ttcgcgatcg
    25681 cggatgttga ccttgccatc aatcatgccg tcaatgctca gttgcgcctg cgcaatccgc
    25741 tgtttgtctt cgccatcttt tgtttcgacg taatactcga tggtgtggct gttaaagcca
    25801 tccgccaggg tgacgtaaat acgaaaatgt tcaaaaagga cgaaacagag ttctttgtcc
    25861 ggcgcgcagc tcatggcgtg atgcaggcgc gctttcgata acgtgatccc ctgaaccagc
    25921 gaattgcagt agatgtgcca ctggtcctgt aggcgacgat gccgctgtgc gatgtaatcg
    25981 gctttctcgc ttatttccca aatagtcatt gtcaggttac ccgtttaaca gagatgccag
    26041 ctttaagcat tttttgtgcc aacttttaat ttattgttat taaagagatt tttaagctaa
    26101 agatgaattt cgtcgccgtg tcgacgtgtc atttcgacat catcgacatt attcaccgca
    26161 gggataatca acactggcac aattattgct tgtagctggc aatagttaat gggaggcgat
    26221 atgcacgaaa taaccctctg ccaacgggca ctggaattga tcgaacagca ggccgcaaaa
    26281 cacggcgcaa aacgcgtaac tggggtctgg ctcaaaattg gcgcattttc ttgtgtcgaa
    26341 accagctctc ttgccttttg ttttgatctg gtttgccgcg gcagcgtggc ggaaggttgt
    26401 aaactgcacc tcgaagaaca agaggccgaa tgctggtgtg aaacatgcca acagtatgtg
    26461 acgctactga cccagcgcgt ccgccgctgt ccacagtgtc atggtgacat gctacagatt
    26521 gtggcagacg acggtttaca gattcggcgg atagaaatag accaggagtg agcgatgtgt
    26581 acaacatgcg gttgcggtga aggcaacctg tatatcgagg gtgatgaaca taaccctcat
    26641 tccgcgtttc gtagcgcgcc atttgccccg gcggcacgcc cgaagatgaa aatcaccggc
    26701 attaaagcgc ctgaatttac ccccagccag actgaagaag gcgacctgca ttacggtcat
    26761 ggcgaagcgg gcactcacgc accgggcatg agccagcgtc ggatgctgga agtcgaaatt
    26821 gacgtgctgg acaaaaacaa ccgtctggct gaacgcaacc gcgcgcgctt tgctgcccgc
    26881 aagcaactgg tgctcaacct ggtttccagc cctggttccg gtaaaaccac cctgctgacg
    26941 gaaaccttaa tgcgcctgaa agacagcgtt ccgtgcgcgg ttattgaagg tgaccagcaa
    27001 accgtgaacg atgccgcacg cattcgcgct accggcacac cagcgattca ggtgaacacc
    27061 ggtaaaggct gccatcttga cgcacagatg attgccgacg ccgcaccgcg tctgccactg
    27121 gacgataacg gtattctgtt tatcgaaaac gttggcaacc tcgtatgccc ggccagcttc
    27181 gatctcggtg aaaaacacaa agtggcggtg ctttccgtta ccgaaggtga agacaaaccg
    27241 ctgaaatatc cgcatatgtt tgccgccgcc tcgctgatgc tgctcaacaa agttgacctg
    27301 ttgccgtatc tcaactttga cgttgaaaag tgcatcgcct gcgcccgcga agtcaatcca
    27361 gaaattgaaa tcatccttat ttccgccacc agcggcgaag ggatggacca gtggctgaac
    27421 tggctggaga cacagcgatg tgcataggcg ttcccggcca gatccgcacc attgacggca
    27481 accaggcgaa agtcgacgtc tgcggcattc agcgcgatgt cgatttaacg ttagtcggca
    27541 gctgcgatga aaacggtcag ccgcgcgtgg gccagtgggt actggtacac gttggctttg
    27601 ccatgagcgt aattaatgaa gccgaagcac gcgacactct cgacgcctta caaaacatgt
    27661 ttgacgttga gccggatgtc ggcgcgctgt tgtatggcga ggaaaaataa tgcgttttgt
    27721 tgatgaatat cgcgcgccgg aacaggtgat gcagttaatt gagcatctgc gcgaacgtgc
    27781 ttcacatctc tcttacaccg ccgaacgccc tctgcggatt atggaagtgt gtggcggtca
    27841 tacccacgct atctttaaat tcggcctcga ccagttactg ccggaaaacg ttgagtttat
    27901 ccacggtccg gggtgcccgg tgtgcgtact gccgatgggt agaatcgaca cctgcgtgga
    27961 gattgccagc catccggaag tcatcttctg tacctttggc gacgccatgc gcgtaccagg
    28021 gaaacagggt tcgctgttgc aggcaaaagc acgcggtgcc gatgtgcgca tcgtttactc
    28081 gccgatggat gcgttgaaac tggcgcagga gaatccaacc cgcaaagtgg tgttcttcgg
    28141 cttaggtttt gaaaccacca tgccgaccac cgccatcact ctgcaacagg cgaaagcgcg
    28201 tgatgtgcag aatttttact tcttctgcca gcatattacg cttatcccga cgcttcgcag
    28261 tttgctggaa cagccggata acggtatcga cgcgttcctc gcgccgggcc acgttagtat
    28321 ggttatcggc actgatgcct ataattttat cgccagcgat tttcatcgtc cgctggtggt
    28381 ggctggtttc gaaccgcttg atctactgca aggcgtggtc atgctggtgg agcagaaaat
    28441 agcggcccac agcaaggtag agaatcagta tcgtcgggtg gtaccggatg ccggtaacct
    28501 gctggcgcaa caggcgattg ccgatgtgtt ctgtgtcaac ggcgacagcg aatggcgcgg
    28561 cttaggcgtg attgaatctt ctggtgtaca cctgacgcca gattatcaac gattcgatgc
    28621 cgaagcgcat ttccgcccgg caccgcagca ggtctgcgat gacccgcgcg cacgttgtgg
    28681 tgaagtatta acgggcaaat gtaagccgca tcaatgcccg ctgtttggta acacctgtaa
    28741 tcctcaaacc gcatttggtg cactgatggt ctcctccgaa ggagcgtgcg ccgcgtggta
    28801 tcagtatcgt cagcaggaga gtgaagcgtg aataatatcc aactcgccca cggcagcggc
    28861 ggccaggcga tgcagcaatt aatcaacagc ctgtttatgg aagcctttgc caacccgtgg
    28921 ctggcagaac aggaagatca ggcacgtctt gagctggcgc agctggtagc ggaaggcgac
    28981 cgtctggcgt tctccaccga cagttacgtc attgacccgc tgttctttcc tggcggtaat
    29041 atcggcaagc tggcgatttg cggcactgcg aatgacgttg cggtcagtgg cgctattccg
    29101 cgctatctct cctgtggctt tatcctcgaa gaaggattgc cgatggagac actgaaagcc
    29161 gtagtgacca gcatggcaga aaccgcccgc acggcaggca ttgccatcgt tactggcgat
    29221 actaaagtgg tgcagcgcgg cgcggcagat aaactgttta tcaacaccgc tggcatgggc
    29281 gcaattccgg cgaatattca ctggggcgca cagacgctaa ccgcaggcga tgtattactg
    29341 gttagcggca cgctcggcga ccacggggcg actatcctta acctgcgtga gcagctgggg
    29401 ctggatggcg aactggtcag cgactgcgcg gtactgacgc cgcttattca gacgctgcgt
    29461 gacattcccg gcgtgaaagc gctgcgtgat gccacccgtg gtggtgtgaa cgcggtagtt
    29521 catgagttcg cggcagcctg cggttgtggt attgaaattt cagaagcggc actgccggtt
    29581 aaacctgccg tgcgcggcgt ttgcgaactg ctgggactgg acgcccttaa ctttgccaac
    29641 gaaggcaaac tggtgatcgc cgttgaacgc aacgcggcag agcaagtgct ggcagcgtta
    29701 cattcccatc cactgggaaa agacgcggcg ctgattggtg aagtggtgga acgtaaaggt
    29761 gttcgtcttg ccggtctgta tggcgtgaaa cgaaccctcg atttaccaca cgccgaaccg
    29821 cttccgcgta tatgctaata aaattctaaa tctcctatag ttagtcaatg accttttgca
    29881 ccgctttgcg gtgctttcct ggaagaacaa aatgtcatat acaccgatga gtgatctcgg
    29941 acagcaaggg ttgttcgaca tcactcggac actattgcag cagcccgatc tggcctcgct
    30001 gtgtgaggct ctttcgcaac tggtaaagcg ttctgcgctc gccgacaacg cggctattgt
    30061 gttgtggcaa gcgcagactc aacgtgcgtc ttattacgca tcgcgtgaaa aagacacccc
    30121 cattaaatat gaagacgaaa ctgttctggc acacggtccg gtacgccgca ttttgtcgcg
    30181 ccctgatacg ctgcattgca gttacgaaga attttgtgaa acctggccgc agctggtcgc
    30241 aggtgggcta taccccaaat ttggtcacta ttgcctgatg ccactggcgg cggaagggca
    30301 tatttttggt ggctgtgaat ttattcgtta tgacgatcgt ccctggagcg aaaaagagtt
    30361 caatcgtctg caaacattta cgcagatcgt ttctgtcgtc accgaacaaa tccagagccg
    30421 cgtcgtcaac aatgtcgact atgagttgtt atgccgggag cgcgataact tccgcatcct
    30481 ggttgccatt accaacgcgg tgctttcccg cctggatatg gacgaactgg tcagcgaagt
    30541 cgccaaagaa atccattact atttcgacat tgacgatatc agcattgtct tacgcagcca
    30601 ccgtaaaaac aaactcaaca tctactccac tcactatctt gataaacaac atcccgccca
    30661 cgaacagagc gaagtcgatg aagccggaac cctcaccgaa cgcgtgttca aaagtaaaga
    30721 gatgctgctg atcaatctcc acgagcggga cgatttagcc ccctatgaac gcatgttgtt
    30781 cgacacctgg ggcaaccaga ttcaaacctt gtgcctgtta ccgctgatgt ctggcgacac
    30841 catgctgggc gtgctgaaac tggcgcaatg cgaagagaaa gtgtttacca ctaccaatct
    30901 gaatttgctg cgccagattg ccgaacgtgt ggcaatcgct gtcgataacg ccctcgccta
    30961 tcaggaaatc catcgtctga aagaacggct ggttgatgaa aacctcgccc tgaccgagca
    31021 gctcaacaat gttgatagtg aatttggcga gattattggc cgcagcgaag ccatgtacag
    31081 cgtgcttaaa caagttgaaa tggtggcgca aagtgacagt accgtgctga tcctcggtga
    31141 aactggcacg ggtaaagagc tgattgcccg cgcgatccat aatctcagtg ggcgtaataa
    31201 tcgccgcatg gtcaaaatga actgcgcggc gatgcctgcc ggattgctgg aaagcgatct
    31261 gtttggtcat gagcgtgggg cttttaccgg tgccagcgcc cagcgcattg gtcgttttga
    31321 actggcggat aaaagctctc tgttcctcga cgaagtgggc gatatgccac tggagttaca
    31381 gccgaagttg ctgcgtgtat tgcaggaaca ggagtttgaa cgtctcggca gcaacaaaat
    31441 cattcagacg gacgtacgtt taattgccgc gactaaccgc gatctgaaaa aaatggtcgc
    31501 cgaccgtgag ttccgtagcg atctctatta ccgcctgaac gtattcccga ttcacctgcc
    31561 gccactacgc gagcgtccgg aagatattcc gctgctggcg aaagccttta ccttcaaaat
    31621 tgcccgtcgt ctggggcgca atatcgacag cattcctgcc gagacgctgc gcaccttgag
    31681 caacatggag tggccgggta acgtacgcga actggaaaac gtcattgagc gcgcagtatt
    31741 gctaacacgc ggcaacgtgc tgcagctgtc attgccagat attgctttac cggagcctga
    31801 aacgccgcct gccgcaacgg ttgtcgccca ggagggcgaa gatgaatatc agttgattgt
    31861 gcgcgtgctg aaagaaacca acggcgtggt tgccgggcct aaaggcgctg cgcaacgtct
    31921 ggggctgaaa cgcacgaccc tgctgtcacg gatgaagcgg cttggaattg ataaatcggc
    31981 attgatttaa ctgcaaattg ccggacagat ctgcctgtcc ggcatactat tcacgagttt
    32041 ttttcggacg atatttttcc ggcagttctg gcaccggacg cttgtcatcg atgagatgac
    32101 gcacggttaa gatcggatga cgccacagca ttcgcggccc ggcccaacgc ataatctgtt
    32161 tcatctcttc acgctttgct ggctggtaac agtgcaccgg acactgctta caggctggtt
    32221 tctcttcgcc gaacacacat ttatccagcc gcttttgcgc gtaaacaaac aacgcctcgt
    32281 aatgctccgg ctccgctgac gcctgcgggc atttcgcttg ataaagatcg atcatttttt
    32341 taatcgtcag tttttcacga gagatacgct tgccggacat gctgcctcca cctcattaag
    32401 atgtatttat attacatctt aatcttaaag ggcactatga ctctaaagaa gaaaggttcg
    32461 ccaaccgacg caattttgcg tacttgcttc ataagcatca cgcaaaagct gcaaaacagc
    32521 atctttcccg gaaccagcat caagaactca ccgttcgctt cttcccctga aatgattaac
    32581 tccggtatca tgtgcgcctt atgtgattac aacgaaaata aaaaccatca caccccattt
    32641 aatatcaggg aaccggacat aaccccatga gtgcaataga aaatttcgac gcccatacgc
    32701 ccatgatgca gcagtatctc aggctgaaag cccagcatcc cgagatcctg ctgttttacc
    32761 ggatgggtga tttttatgaa ctgttttatg acgacgcaaa acgcgcgtcg caactgctgg
    32821 atatttcact gaccaaacgc ggtgcttcgg cgggagagcc gatcccgatg gcggggattc
    32881 cctaccatgc ggtggaaaac tatctcgcca aactggtgaa tcagggagag tccgttgcca
    32941 tctgcgaaca aattggcgat ccggcgacca gcaaaggtcc ggttgagcgc aaagttgtgc
    33001 gtatcgttac gccaggcacc atcagcgatg aagccctgtt acaggagcgt caggacaacc
    33061 tgctggcggc tatctggcag gacagcaaag gtttcggcta cgcgacgctg gatatcagct
    33121 ccgggcgttt tcgcctgagc gaaccggccg accgcgaaac gatggcggca gagctgcaac
    33181 gcactaatcc ggcggaactg ctgtatgcag aagatttcgc cgagatgtcg ctgattgaag
    33241 gccgtcgcgg cctgcgccgt cgcccgctgt gggagtttga aatcgacacc gcgcgccagc
    33301 agttgaatct gcaatttggc actcgcgatc tggtcggttt tggcgtcgag aacgcgccgc
    33361 gcggactttg tgctgccggt tgtctgttgc agtatgcgaa agatacccaa cgtacgactc
    33421 tgccgcatat tcgttccatc accatggaac gtgagcagga cagcatcatt atggatgccg
    33481 cgacgcgtcg taatctggaa atcacccaga acctggcggg tggtgcggaa aatacgctgg
    33541 cttctgtgct cgactgcacc gtcacgccga tgggcagccg tatgctgaaa cgctggctgc
    33601 atatgccagt gcgcgatacc cgcgtgttgc ttgagcgcca gcaaactatc ggcgcattgc
    33661 aggatttcac cgccgagttg cagccggtac tgcgtcaggt cggcgacctg gaacgtattc
    33721 tggcacgtct ggctttacga actgctcgcc cacgcgatct ggcccgtatg cgccacgctt
    33781 tccagcaact gccggagctg cgtgcacagt tagaaactgt cgatagtgca ccggtacagg
    33841 cgctacgtga gaagatgggc gagtttgccg agctgcgcga tctgctggag cgagcaatca
    33901 tcgacacacc gccagtgctg gtacgcgacg gtggtgttat cgcatcgggc tataacgaag
    33961 agctggatga gtggcgcgcg ctggctgacg gcgcgaccga ttatctggag cgtctggaag
    34021 tccgcgagcg tgaacgtacc ggcctggaca cgctaaaagt tggctttaat gcggtgcacg
    34081 gctactacat tcaaatcagc cgtgggcaaa gccatctggc acccatcaac tacatgcgtc
    34141 gccagacgct gaaaaacgcc gagcgctaca tcattccaga gctaaaagag tacgaagata
    34201 aagttctcac ctcaaaaggc aaagcactgg ctctggaaaa acagctttat gaagaactgt
    34261 tcgacctgct gttgccgcat ctggaagcgt tgcaacagag cgcgagcgcg ctggcggaac
    34321 tcgacgtgct ggtgaacctg gcggaacggg cctataccct gaactacacc tgcccgacct
    34381 ttattgataa accgggcatt cgcattaccg aaggccgcca tccggtggtt gaacaggtgc
    34441 tgaatgagcc gtttatcgcc aacccgctga atctgtcgcc gcagcgtcgc atgttgatca
    34501 tcaccggtcc gaacatgggc ggtaaaagta cctatatgcg ccagaccgcg ttgattgcgc
    34561 taatggccta tatcggcagc tacgtaccgg cgcaaaaagt cgagattggc ccgattgacc
    34621 gtatctttac ccgcgtaggc gcggcagatg acctggcttc cgggcgttcg acctttatgg
    34681 tggagatgac cgaaaccgcc aatattttac ataatgccac cgaatatagt ctggtattga
    34741 tggatgagat cgggcgtgga acgtccactt acgatggtct gtcgctggcg tgggcgtgcg
    34801 cggaaaatct ggcgaataag attaaggcat tgacgctgtt tgccacccac tatttcgagc
    34861 tgacacagtt accggagaaa atggaaggcg tcgccaacgt gcatctcgat gcactggagc
    34921 acggcgacac cattgccttt atgcacagcg tgcaggatgg cgcggcgagc aaaagctacg
    34981 gcctggcggt tgcagctctg gccggcgtgc caaaagaggt tattaagcgc gcacggcaaa
    35041 agctgcgtga gctggaaagc atttcgccga acgccgccgc tacgcaagta gatggtacgc
    35101 aaatgtcttt gctgtccgta ccagaagaaa cttcgcctgc ggtcgaggca ctggaaaacc
    35161 tggacccgga ttcactgact ccgcgtcagg cgctggagtg gatttatcgc ttgaagagtc
    35221 tggtgtaata aaaattcccg atagtctttt gctatcggga atattaacga caactgacga
    35281 atcaaataaa aataccctgt ataataggaa agcttatttt acagggtaaa accatgccat
    35341 ctacacgcta tcaaaaaatc aatgcccatc actatcgcca tatatgggtc gttggtgata
    35401 ttcatggtga atatcagtta ttacaatccc gcttacatca actctctttt ttccccgaaa
    35461 ccgacttact tatttctgtc ggcgataata ttgatcgtgg gccggagagt cttgacgtcc
    35521 tgcgcctgct aaaccagccc tggtttatct ccgttaaagg caaccacgaa gcaatggcgc
    35581 tggatgcgtt cgcgaccggc gatggcaata tgtggcttgc cagcggtggt gactggtttt
    35641 tcgatttaaa tgattcagag caaaaagaag ctacagatct gttgctgaaa ttccatcacc
    35701 ttccacatat tattgaaatc actaacgaca acataaaata tgtcatcgca catgcagatt
    35761 atccggggag tgaatatctc tttggtaaag aaatagcgga gagcgaatta ctctggcctg
    35821 ttgatcgtgt gcagaaatcg cttaatggcg agttacaaca aataaacggc gctgattatt
    35881 ttatatttgg acatatgatg tttgataaca ttcagacgtt cgctaaccag atttatattg
    35941 ataccggatc gccgaaaagt gggcggctgt cattttataa aataaggtag tctcatgctt
    36001 cttctgtgaa gcatgagtaa ccagatgtta ttgcaggcca ttattcattt ttcgctacca
    36061 gcaaagagag atcctgcttc gccagcgcgc gactggcact ctccggcaaa ccgtcgtctg
    36121 taataatctg atcaaactcg cttaatggta acgccagcca tgtcgccacc tgaccatatt
    36181 tcgtcgcatc acagaccaaa actcgctggc ggctggcact ggcaatcgcc cgtttcaccg
    36241 tgactttatc ttccgctggc gtagaaatcc cccgcacact ccatgacgat gcagaaataa
    36301 aagcctgatc aatcatcagg ctgcgcagca tggtcgcagc ggcttccccg acacaggaac
    36361 ggttttcccg acacactgca ccgccagtgt gaataattgt gcaattactg ttgtcgagca
    36421 agtagttcgc aataacgaaa tcgtttgtga ccacagtcag tgactccatg tgaatcagat
    36481 gctgtgctat cgctaacgtg gtcgttcccg catccagata gatacaactt cccggctgaa
    36541 caagacttgc cgccagcttg ccaatagccg ctttttgcgt cattgccagc gcagttttta
    36601 cctgatgaga aggttcatgc gccacgcgtc ccggagactg gacgcctccg gacaccagca
    36661 caacggctcc ctgctgctcc agtttttgta aatcccgacg aatggtcata tgtgacacat
    36721 tcattctgtc cgttagttca gcaatactga caatgccttt ttcagctacc atctcaagga
    36781 tgatttggcg acgctctacg ggtatcaact tttgctcctt cctttgtcct gctgacattc
    36841 tacgctattt gcctgcgaaa cgtgcgcggc gcaactaacg cttagttcac ataaaataac
    36901 acacaatgtt aatttatgtg aatcagctca ccatatcgtt atcttccagc gcttatattc
    36961 acaatatcaa acaaaatatc acttaaatta acaaggagag cagatgaaaa cgggatctga
    37021 gtttcatgtc ggtatcgttg gcttagggtc aatgggaatg ggagcagcac tgtcatgtgt
    37081 ccgcgcaggt ctttctacct ggggcgcaga cctgaacagc aatgcctgcg ctacgttgaa
    37141 agaggcaggt gcttgcgggg tttctgataa cgccgcgacg tttgccgaaa aactggacgc
    37201 tctgctggtg ctggtggtca atgcggccca ggttaaacag gtgctgtttg gtgaaacagg
    37261 cgttgcacaa catctgaaac ccggtacggc agtaatggtt tcttccacta tcgctagtgc
    37321 tgatgcgcaa gaaattgcta ccgctctggc tggattcgat ctggaaatgc tggatgcgcc
    37381 agtttctggt ggtgcagtaa aagccgctaa cggtgaaatg actgtcatgg cctccggtag
    37441 cgatattgcc tttgaacgac tggcacccgt gctggaagcc gttgccggaa aagtttatcg
    37501 cataggtgca gaaccgggac taggttcgac cgtaaaaatt attcaccagt tgttagcggg
    37561 cgtacatatt gctgccggag ccgaagcgat ggcacttgca gcccgtgcgg ggatcccgct
    37621 ggatgtgatg tatgacgtcg tgaccaatgc cgccggaaat tcctggatgt tcgaaaaccg
    37681 gatgcgtcat gtggtggatg gcgattacac cccgcattca gccgtcgata tttttgttaa
    37741 ggatcttggt ctggttgccg atacagccaa agccctgcac ttcccgctgc cattggcctc
    37801 aacagcattg aatatgttca ccagcgccag taacgcaggt tacgggaaag aagacgatag
    37861 cgcagttatc aagattttct ctggcatcac tctaccggga gcgaaatcat gatcaagatt
    37921 ggcgttatcg ccgatgattt taccggcgcg acggatatcg ccagttttct ggtggaaaac
    37981 ggtctaccaa cggtacaaat taacggtgtt ccaacaggta aaatgccgga agcaatcgac
    38041 gcactggtga tcagcctgaa aacgcgctcc tgtccggtgg ttgaagccac acagcaatcg
    38101 ctggcggctc tgagctggtt gcaacagcaa ggttgcaaac agatctattt caaatactgc
    38161 tctactttcg acagtacggc gaaaggtaat atcggcccgg ttaccgatgc attaatggat
    38221 gctctcgaca cgccgtttac ggtcttctct ccggccctgc cggtcaacgg acgtacggtt
    38281 tatcaggggt atttgttcgt aatgaatcaa ctgctggccg aatccgggat gcgccatcac
    38341 ccggtaaatc ccatgaccga cagctatctt ccccgtctgg ttgaagcgca atccacaggg
    38401 cgctgcggcg tcgtttcggc acatgttttc gaacaaggtg tggatgccgt tcgtcaagag
    38461 ctggctcgct tacagcaaga gggctaccgc tacgcggtgc ttgatgcgct gaccgaacac
    38521 catctggaaa ttcagggaga agccttgcgc gatgccccac tggtaacggg cggttctggt
    38581 ctggcgattg gcctggcccg gcagtggacg caagaaaacg gtaaccaggc tcgcaaagca
    38641 gggcatccgc tcgctgggcg cggcgtagtg ctctccggtt catgctctca aatgaccaac
    38701 cgccaggtag cacattaccg tcaaattgca ccagcccgtg aagttgatgt ggcacgctgc
    38761 ctctcaactg aaactctggc tacttatgca cacgaactgg cagagtgggt tctgggccag
    38821 gaaagtgtac ttgctccact ggtttttgcc accgccagca ctgacgcatt ggcagcaatt
    38881 caacagcaat acggtgcaca aaaagccagt caggcagtag aaacactgtt ttctcaacta
    38941 gcggcgcggt tagcggcgga aggcgtggca cgctttattg tcgcaggcgg tgagacctcc
    39001 ggcgtagtca cacagagcct gggcataaaa gggtttcata ttggcccaac catttccccc
    39061 ggcgtgccgt gggtaaacgc actggataag cctgtctcac tcgcccttaa atctggcaac
    39121 ttcggtgatg aagccttttt ttcacgagcc caaagagagt ttttatcatg agcgatttcg
    39181 caaaagtaga gcagtctttg cgagaggaga tgacgcggat tgccagttca ttctttcagc
    39241 gcggctatgc aaccggttcg gctggcaatc tgtcgctgct tttacctgac gggaatttac
    39301 tggcgacacc gacaggttca tgcctgggca atctcgatcc gcagcggctt tccaaagtcg
    39361 ccgcggatgg cgaatggtta agtggtgaca aaccctcgaa agaggtgctc tttcatctgg
    39421 cgctgtatcg caacaatccg cgctgtaaag cggtggtgca tttgcacagc acatggtcga
    39481 cggcgctttc ctgcctgcaa gggctggaca gcagcaacgt tattcgtccg ttcacaccat
    39541 acgtggtgat gcggatggga aatgtcccgc tggtgcctta ttaccgaccg ggcgataaac
    39601 gcatcgcaca ggatctggcg gaactggcag cagacaatca ggctttttta ctggcaaatc
    39661 atggcccagt ggtttgcggt gaaagcctgc aagaagccgc caacaatatg gaagagctgg
    39721 aggaaacggc aaagctgatt tttattctcg gtgaccgccc gatccgttat ctgaccgcag
    39781 gtgaaattgc ggaattaagg agttaatgca atgcctcgtt ttgcagctaa tttatccatg
    39841 atgttcaccg aagtgccttt tattgaacgc ttcgccgcag cgcgaaaagc cgggttcgat
    39901 gctgtggaat ttctgtttcc ctatgactac tccaccctgc aaatccaaaa gcaactggag
    39961 caaaaccatc tgacactggc gctgttcaat accgctcccg gagatattaa tgcgggggaa
    40021 tggggattat ccgcccttcc cggacgtgag cacgaagcac acgcagacat cgacctggca
    40081 ctggaatatg cattggcgct caattgtgaa caagtccatg tgatggcagg cgtcgtgccc
    40141 gctggcgaag acgctgaacg gtaccgggca gtatttatcg ataatctccg ctacgctgcc
    40201 gaccgctttg cgccacacgg caagcgaata ttagttgaag cactcagccc cggcgttaag
    40261 cctcattatc tcttctccag ccagtatcag gcactggcta ttgttgaaga ggttgcgcga
    40321 gataacgtgt ttattcaact agatactttt catgcgcaaa aagtagatgg caacctgacg
    40381 catttaatcc gcgactacgc tgggaaatat gcgcacgtac aaattgccgg actacctgat
    40441 cgacatgaac cggacgatgg agaaatcaac tatccgtggc tgttccgcct gttcgatgag
    40501 gtgggatatc agggctggat cggttgtgaa tataaacctc gtggcctcac cgaagaaggg
    40561 cttggctggt ttgacgcctg gcgctaattc gttaaatccc taattacaac gtacccatac
    40621 atccccccat ctacggatgg ggtaggttaa ctataacttt cagacagggt ttcccatgtc
    40681 cacaattaca ttgttatgca ttgcgttagc tggcgtaatc atgctgttgc tgctggtcat
    40741 caaggcaaag gtacaaccat tcgttgctct gctcctcgtc agcctgttag tcgcacttgc
    40801 ggcgggtata ccggcgggcg aagtgggtaa agtgatgatc gccgggatgg gcggtgtgct
    40861 tggttccgtc actattatta ttggtctggg cgctatgctg gggcgtatga tcgaacactc
    40921 tggtggtgca gagtcactgg ctaattattt cagtcgcaag ttaggtgaca aacgaactat
    40981 cgctgcgctg actctggcag cgttcttcct cggtattccc gtcttctttg atgtcggctt
    41041 tattattctt gcgccaatca tttacggttt tgccaaggtt gccaaaatat cgccactcaa
    41101 atttggcctg cctgtcgctg gaatcatgct aactgttcat gtggcggtac cgccgcatcc
    41161 aggccctgtc gccgcagcgg ggttactcca cgcagacatc ggctggctaa ccatcatcgg
    41221 tattgcgatt tctattcccg tagggattgt tggctacttt gcagcgaaaa taatcaatac
    41281 gcgccaatat gcgatgtcgg tggaagtact ggaacagatg caactggctc cggccagtga
    41341 ggaaggcgca acaaaattaa gcgataaaat aaatccaccg ggcgtcgcgc tggtcacctc
    41401 gctaattgtt attcctatcg cgattatcat ggcgggtacg gtttccgcaa cactgatgcc
    41461 gccttcgcat cccctgcttg gtacgctaca gctgatcggc tcaccaatgg tagctctaat
    41521 gattgcgctg gtgctggcat tctggttatt ggctttacgt cgcggctgga gcttacaaca
    41581 caccagcgac attatgggct cagcccttcc cactgcggcg gtagtgattt tggttactgg
    41641 tgctggaggg gtatttggca aagtgctggt ggaatcgggc gtcggcaaag cccttgccaa
    41701 tatgctacaa atgattgacc tgcctctgtt accagccgca tttattattt cactggctct
    41761 gcgtgcatcg caggggtcag caaccgtagc aatcctgaca accggcgggt tactctcaga
    41821 agcggtgatg ggattgaatc cgattcagtg cgtattggtg acgctggcag cctgctttgg
    41881 tgggcttggc gcgtcacata ttaatgactc agggttctgg attgtgacca aatatctggg
    41941 gttgtcggta gcagacggtc tgaaaacctg gacagtgtta acgaccattc tcggttttac
    42001 cggattctta attacctggt gcgtatgggc ggtaatttga ccttaataaa aaggtccgat
    42061 gggcatcgga ccttttattt aacgcttacc ttccaccagc agcggcggga tgctcggcac
    42121 cattggcgcg tcatcaatat ctttctgcgt catgcggaac gcttcgggat aatgttcgcg
    42181 gctggtacgg cgcagcggtt cggtatcgcg cagcggttcg gtatcgcgcc aggtataaag
    42241 gcaatgctgg cactgatata ccgtccagac atctttcacc ggcgatttcg ccatcacttc
    42301 aatctgttca tcggcacaac gtggacaaat catcttcttc tccttattta cgtgcagcca
    42361 gcatagcggt cagtttttca gcccaggctt tggtttccgg taaatccacc accggttggc
    42421 tgtagtgacc acggttgtcc ggggcgacag gcgtagtggc gtcgataatc agcttgtcgg
    42481 tgatccccgc agggcttgag cctggatcga gttccagcac ggacatattc ggcaactgca
    42541 ccaaatcccc tgccgggttc actttcgagg agagcgccca catcacctgc ggcaggttga
    42601 acgggtcaac gtcttcatcg accataatca ccatcttcac gtagcccaga ccatgcggcg
    42661 tggtcattgc gcgcaggccc accgcgcggg caaagccgcc gtagcgtttt ttggtggaga
    42721 taatcgccag caggccatgg gtgtacatgg cgtttaccgc ctgcacttca gggaactcgg
    42781 ctttcagctg ctgatacagc ggcacgcagg tggctggccc catcaggtag tcgatttcgg
    42841 tccacggcat accgaggtac agcgattcga aaatcggcct ggtgcggtaa gagactttat
    42901 cgatgcgcac cacggtcatg ttacgcccgc cggagtagtg cccggtaaac tcaccgaacg
    42961 gcccttcgat ttcgcgttta cggctttcga tgaccccttc gaggatcact tctgaacccc
    43021 acggcacatc aaaaccggtc aacggggcgg tggcgatcgg gtacgggctt tcacgcagcg
    43081 cgcctgccat ttcgtactcg gactgatcat atttcagcgg cgtggccccc atcagcgtga
    43141 tgatcggatc gttaccgagc gtgatcgcaa tcggcagatc ttcaccgcgc tcttctgctt
    43201 tatgcagatg cagggcgata tcgtgcatcg gcaccggttg caggccgagc ttacgcttgc
    43261 ccttcacttc catgcggtag atgccgacgt tctgcttgcc gaagttatcc gggtcgagcg
    43321 gatcgcggga aaccacgcac gctttgtcga gatagaaacc gccatcgcca tcgtttaaac
    43381 gaaacagcgg caggatatcg aacaggttaa tctcttcgcc atc
//
LOCUS       DAZUDJ010000038        43051 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.038, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000038 DAZUDJ010000000
VERSION     DAZUDJ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43051
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.038"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            73..942
                     /gene="robA"
                     /locus_tag="ACHY1N_002771"
     CDS             73..942
                     /gene="robA"
                     /locus_tag="ACHY1N_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HFS4045062.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR
                     YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVM
                     LQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRP
                     INLRCELLIPIRR"
     gene            complement(939..1586)
                     /gene="gpmB"
                     /locus_tag="ACHY1N_002772"
     CDS             complement(939..1586)
                     /gene="gpmB"
                     /locus_tag="ACHY1N_002772"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HFS4045063.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAK
                     ELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEEN
                     WRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR"
     gene            1638..2159
                     /gene="yjjX"
                     /locus_tag="ACHY1N_002773"
     CDS             1638..2159
                     /gene="yjjX"
                     /locus_tag="ACHY1N_002773"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/xanthosine triphosphatase"
                     /protein_id="HFS4045064.1"
                     /translation="MHQVVCATTNPAKIQSILQAFHEIFGEGSCHIASVAVESGVPEQ
                     PFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSA
                     TLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVIL
                     ALSPFHNAVYQAL"
     gene            complement(2244..2570)
                     /gene="trpR"
                     /locus_tag="ACHY1N_002774"
     CDS             complement(2244..2570)
                     /gene="trpR"
                     /locus_tag="ACHY1N_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HFS4045065.1"
                     /translation="MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLT
                     PDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEE
                     VLLKSD"
     gene            complement(2660..4597)
                     /gene="sltY"
                     /locus_tag="ACHY1N_002775"
     CDS             complement(2660..4597)
                     /gene="sltY"
                     /locus_tag="ACHY1N_002775"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0008933 - lytic transglycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HFS4045066.1"
                     /translation="MEKAKQVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAW
                     DNRQMDVVEQMMPGLKDYPLYPYLEYRQITDDLMNQPAVTVTNFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPADYQTIASAI
                     ISLANNPNTVLTFARTTGATDFTRQMAAVAFASVARQDAENARLMIPSLAQAQQLNED
                     QIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVRMALGTGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYE
                     LKIDKAPQNVDSALTQGPEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYA
                     FNNQWWDLSVQATIAGKLWDHLEERFPLAYNDLFKRYTSGKEIPQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPGYSSPGQLLDPETNINIGTSYLQYVYQ
                     QFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRYFMGDKPTLMSATEWGRRY"
     gene            4808..6475
                     /gene="ettA"
                     /locus_tag="ACHY1N_002776"
     CDS             4808..6475
                     /gene="ettA"
                     /locus_tag="ACHY1N_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017145039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0045900 - negative regulation of
                     translational elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HFS4045067.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKI
                     ANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWV
                     RQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYG
                     DRLLIDDLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVD
                     QFRDSMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK"
     gene            complement(6782..8014)
                     /gene="nadR"
                     /locus_tag="ACHY1N_002777"
     CDS             complement(6782..8014)
                     /gene="nadR"
                     /locus_tag="ACHY1N_002777"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418807.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000309 - nicotinamide-nucleotide
                     adenylyltransferase activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0050262 - ribosylnicotinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HFS4045068.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGFDD
                     TRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIDTVLVDPKRTFMSISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     IALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEDDYD
                     SRFLRCVELVREMMGEQR"
     gene            complement(8035..9417)
                     /gene="radA"
                     /locus_tag="ACHY1N_002778"
     CDS             complement(8035..9417)
                     /gene="radA"
                     /locus_tag="ACHY1N_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFS4045069.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKAPEGMQIFGVKKL
                     SDALSVFDDL"
     gene            complement(9466..10434)
                     /gene="serB"
                     /locus_tag="ACHY1N_002779"
     CDS             complement(9466..10434)
                     /gene="serB"
                     /locus_tag="ACHY1N_002779"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036424 - L-phosphoserine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HFS4045070.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEMVAEVTERAMRGELDFTASLHS
                     RVATLKGADANILQQVRENLPLMPGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKL
                     RLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGAND
                     LPMIKAAGLGIAYHAKPKVNEKAEVTIRHADLMGVFCILSGSLNQK"
     gene            10540..11184
                     /gene="ytjB"
                     /locus_tag="ACHY1N_002780"
     CDS             10540..11184
                     /gene="ytjB"
                     /locus_tag="ACHY1N_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HFS4045071.1"
                     /translation="MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQLTDESRILDAGVYDEQGDLIAR
                     SGESVEVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEESEKKE"
     gene            11212..12228
                     /gene="lplA"
                     /locus_tag="ACHY1N_002781"
     CDS             11212..12228
                     /gene="lplA"
                     /locus_tag="ACHY1N_002781"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HFS4045072.1"
                     /translation="MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     SIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITKAFFAHYGERVEA
                     EIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFSWGGVELHFDVEKGHI
                     TRAQVFTDSLNPAPLEALAGRLQGGLYRADMLQQECEALLVDFPDQEKELRELSTWIA
                     GAVR"
     gene            12260..12523
                     /locus_tag="ACHY1N_002782"
                     /pseudo
     CDS             12260..12523
                     /locus_tag="ACHY1N_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313371.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(12684..13403)
                     /gene="deoD"
                     /locus_tag="ACHY1N_002783"
     CDS             complement(12684..13403)
                     /gene="deoD"
                     /locus_tag="ACHY1N_002783"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFS4045073.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLF
                     YSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
     gene            complement(13483..14706)
                     /gene="deoB"
                     /locus_tag="ACHY1N_002784"
     CDS             complement(13483..14706)
                     /gene="deoB"
                     /locus_tag="ACHY1N_002784"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFS4045074.1"
                     /translation="MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEAD
                     NGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGH
                     WEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMS
                     LLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLA
                     KYFGTSDMEYGKAMF"
     gene            complement(14758..16080)
                     /gene="deoA"
                     /locus_tag="ACHY1N_002785"
     CDS             complement(14758..16080)
                     /gene="deoA"
                     /locus_tag="ACHY1N_002785"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009032 - thymidine phosphorylase activity
                     [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HFS4045075.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVT
                     MALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYL
                     PTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQ
                     VDGQRPLAVIHAKDENSWQDAAKAVKAAIKLADKAPESTPTVYRRISE"
     gene            complement(16207..16986)
                     /gene="deoC"
                     /locus_tag="ACHY1N_002786"
     CDS             complement(16207..16986)
                     /gene="deoC"
                     /locus_tag="ACHY1N_002786"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFS4045076.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVD
                     VVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIK
                     AGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAI
                     ADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY"
     gene            17244..18794
                     /gene="yjjI"
                     /locus_tag="ACHY1N_002787"
     CDS             17244..18794
                     /gene="yjjI"
                     /locus_tag="ACHY1N_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HFS4045077.1"
                     /translation="MPTSHENALQQRCQQIVTSPVLSPEQKRHFLALEAENNLPYPQL
                     PAEARRALDEGVICDMFEGHAPYKPRYVLPDYARFLANGSEWLELEGAKDLDDALSLL
                     TILYHHVPSVTSMPVYLGQLDALLQPHVRILTQDEIDIRIKRFWRYLDRTLPDAFMHA
                     NIGPSDSPITRAILRADAELKQVSPNLTFIYDPEITPDDLLLEVAKNICECSKPHIAN
                     GPVHDKIFTKGGYGIVSCYNSLPLAGGGSTLVRLNLKAIAERSESLDDFFTRTLPHYC
                     QQQIAIIDARCEFLYQQSHFFENSFLVKEGLINPERFVPMFGMYGLAEAVNLLCEKEG
                     IAARYGKEAAANEVGYRISAQLAEFVANTPVKYGWQKRAMLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAYYYSGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLEKYRAEGSRTNTTWLGEEAARNTRILERQPRVISH
                     EQQMRFSQ"
     gene            18766..19629
                     /gene="yjjW"
                     /locus_tag="ACHY1N_002788"
     CDS             18766..19629
                     /gene="yjjW"
                     /locus_tag="ACHY1N_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HFS4045078.1"
                     /translation="MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNDCGECVPQCPHQALQIVDGKVVWNAVVCEQCDTCLKRCPQHATPMAQSMSVDEV
                     LSHVRKAVLFIEGITVSGGEATTQLPFVVALFTAIKNDPQLRHLTCLVDSNGMLSETG
                     WEKLLPVCDGAMLDLKAWGSECHQQITGRDNQQIKRSICLLAERGKLAELRLLVIPGQ
                     VDYLQHIEELAAFIKGLGDVPVRLNAFHAHGVYGEAQSWASATPEDVEPLADALKVRG
                     VSRLIFPALYL"
     gene            complement(20044..20826)
                     /gene="yjjV"
                     /locus_tag="ACHY1N_002789"
     CDS             complement(20044..20826)
                     /gene="yjjV"
                     /locus_tag="ACHY1N_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFS4045079.1"
                     /translation="MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAE
                     NFARVQALAEKYQPLYAALGLHPGMLEKHSDVSLEQLQQALERRPAKVVAVGEVGLDL
                     FGDDPQLERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLSRTGVVHGFS
                     GSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDAPDMPLNGFQG
                     KPNRPEQAVRVFDVLCELRPEPEDEIAEVLLNNTYAVFSVRG"
     gene            complement(20823..21896)
                     /gene="yjjU"
                     /locus_tag="ACHY1N_002790"
     CDS             complement(20823..21896)
                     /gene="yjjU"
                     /locus_tag="ACHY1N_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HFS4045080.1"
                     /translation="MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFDLYLGTSAGAQNLSAFICNQPGYARKVIMRYTTKREFFDPLRFVRGGN
                     LIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVI
                     RASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQ
                     WFKRMERWLGDSSLQPLVNLVQHHETSYRDIQQFIEKPPGKLRIFEIYPPKPLHSIAL
                     GSRIPALREDYKLGRLCGRYFLATVGKLLTEKAPLTRHLVPVVTPESIVIPPAPVAND
                     TLVAEVIDAPQANDPTFNNEDLA"
     gene            complement(22018..22179)
                     /gene="ytjA"
                     /locus_tag="ACHY1N_002791"
     CDS             complement(22018..22179)
                     /gene="ytjA"
                     /locus_tag="ACHY1N_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HFS4045081.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLV
                     SLFMGRKRP"
     gene            complement(22306..22911)
                     /gene="osmY"
                     /locus_tag="ACHY1N_002792"
     CDS             complement(22306..22911)
                     /gene="osmY"
                     /locus_tag="ACHY1N_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HFS4045082.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVD
                     SSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEA
                     VKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRHVKVE
                     TTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK"
     gene            complement(23304..24893)
                     /gene="prfC"
                     /locus_tag="ACHY1N_002793"
     CDS             complement(23304..24893)
                     /gene="prfC"
                     /locus_tag="ACHY1N_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFS4045083.1"
                     /translation="MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAG
                     TVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRT
                     LTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
                     ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAA
                     VGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWA
                     PAPMPRQTDTRTVQASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQV
                     RTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPN
                     FAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVV
                     SRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSM
                     VNLRLAQERYPDVQFHQTREH"
     gene            complement(24984..25661)
                     /gene="yjjG"
                     /locus_tag="ACHY1N_002794"
     CDS             complement(24984..25661)
                     /gene="yjjG"
                     /locus_tag="ACHY1N_002794"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HFS4045084.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGAITSLQLQHGRFESWAERLKVEAGLLNDAFINAMAEICTPLPGAVS
                     LLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYAL
                     EQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHHREQPEGIAPTWTVSSLHEL
                     EQLLCKH"
     gene            complement(25676..26122)
                     /gene="rimI"
                     /locus_tag="ACHY1N_002795"
     CDS             complement(25676..26122)
                     /gene="rimI"
                     /locus_tag="ACHY1N_002795"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006474 - N-terminal protein amino acid
                     acetylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFS4045085.1"
                     /translation="MNTISSLETTDLPAAYHIEQRAHAFPWSEKTFASNQGERYLNFQ
                     LTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRVLLEHLIDELEKRGVATLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM"
     gene            complement(26091..26504)
                     /gene="holD"
                     /locus_tag="ACHY1N_002796"
     CDS             complement(26091..26504)
                     /gene="holD"
                     /locus_tag="ACHY1N_002796"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HFS4045086.1"
                     /translation="MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPAHVRLVMVAN
                     DLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSRCNSWRLGTDEPLSLEGAQ
                     VASPALTELRANPTARAALWQQICTYEHDFFPRND"
     gene            26607..27638
                     /gene="rsmC"
                     /locus_tag="ACHY1N_002797"
     CDS             26607..27638
                     /gene="rsmC"
                     /locus_tag="ACHY1N_002797"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008990 - rRNA
                     (guanine-N2-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HFS4045087.1"
                     /translation="MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRA
                     HTQQFHHWQVLSRQMGDNARFSLVATVDDVADCDTLIYYWPKNKPEAQFQLMNLLSLL
                     PVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWG
                     EYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHS
                     PKIRLTLCDVSAPAVEASRATLAANGVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRA
                     IMTRQAKKG"
     gene            27906..27992
                     /locus_tag="ACHY1N_002798"
     tRNA            27906..27992
                     /locus_tag="ACHY1N_002798"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27940..27942,aa:Leu,seq:cag)
     gene            complement(28031..28267)
                     /gene="yjjZ"
                     /locus_tag="ACHY1N_002799"
     CDS             complement(28031..28267)
                     /gene="yjjZ"
                     /locus_tag="ACHY1N_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313355.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HFS4045088.1"
                     /translation="MLQRMLGSGWGVLLPGLLIAGLMYADLSPDQWRIVILMGLVLTP
                     VMLYHKQLRHYVLLPSCLALIAGIMLMIMNLNQG"
     gene            28408..29196
                     /gene="fhuF"
                     /locus_tag="ACHY1N_002800"
     CDS             28408..29196
                     /gene="fhuF"
                     /locus_tag="ACHY1N_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HFS4045089.1"
                     /translation="MAYRSAPLYEDIIWRTHLQPQDAGLAQAVRATIAKHREHLLEFI
                     RLDEPAPLNAMTLAQWSSPNALSSLLAVYSDHIYRNQPTMIRENKPLISLWAQWYIGL
                     MVPPLMLALLTQEKALDVSPEHFHAEFHETGRAACFWVDVCEDKNATPHSPQQRMERL
                     ISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEK
                     TLTNGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            complement(29234..29911)
                     /gene="bglJ"
                     /locus_tag="ACHY1N_002801"
     CDS             complement(29234..29911)
                     /gene="bglJ"
                     /locus_tag="ACHY1N_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418786.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HFS4045090.1"
                     /translation="MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGSPYKLHTYTSQ
                     ESFQDAMSRISFTAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLI
                     GSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREI
                     LRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCET
                     SNVLHPY"
     gene            complement(29869..30594)
                     /gene="yjjQ"
                     /locus_tag="ACHY1N_002802"
     CDS             complement(29869..30594)
                     /gene="yjjQ"
                     /locus_tag="ACHY1N_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4045091.1"
                     /translation="MLPGCCKNGIVISKIPVMQAGLKEVMRTHFPEYEIISSASAEDL
                     TLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQYREIHWVFMVSRSWYSQAVELLM
                     CPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERK
                     VLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELN
                     LPSVYGDAAEWNTAELRREMSHS"
     gene            31213..31983
                     /gene="yjjP"
                     /locus_tag="ACHY1N_002803"
     CDS             31213..31983
                     /gene="yjjP"
                     /locus_tag="ACHY1N_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HFS4045092.1"
                     /translation="MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMD
                     SVESSISSNAIVLTTIKDGQCLTSTRKNHDRGINMHVVTEVQHIVILAEHHLLDYKGV
                     EKRFSQIQPLRYPRWLVALMVGLSCACFCKLNKGGWDGAVITFFASTAAMYIRQLLAQ
                     RHLHPQINFCLTAFAATTISGLLLQLPTFSNTPTIAMAASVLLLVPGFPLINAVADMF
                     KGHINTGLARWAIASLLTLATCVGVVMALTIWGLRGWV"
     gene            31974..32447
                     /gene="yjjB"
                     /locus_tag="ACHY1N_002804"
     CDS             31974..32447
                     /gene="yjjB"
                     /locus_tag="ACHY1N_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HFS4045093.1"
                     /translation="MGVIEFLFALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAI
                     GHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV"
     gene            32554..33093
                     /gene="dnaT"
                     /locus_tag="ACHY1N_002805"
     CDS             32554..33093
                     /gene="dnaT"
                     /locus_tag="ACHY1N_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HFS4045094.1"
                     /translation="MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYA
                     VTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFI
                     RLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPK
                     RDVNTVSEPDSQIPPGFRG"
     gene            33096..33833
                     /gene="dnaC"
                     /locus_tag="ACHY1N_002806"
     CDS             33096..33833
                     /gene="dnaC"
                     /locus_tag="ACHY1N_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HFS4045095.1"
                     /translation="MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAAL
                     ERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASF
                     IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDL
                     SNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVM
                     DRMRLGNSLWVIFNWDSYRSRVTGKEY"
     gene            33882..34376
                     /gene="yjjA"
                     /locus_tag="ACHY1N_002807"
     CDS             33882..34376
                     /gene="yjjA"
                     /locus_tag="ACHY1N_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein YjjA"
                     /protein_id="HFS4045096.1"
                     /translation="MMKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNS
                     TTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQYCAKQKLASVTDAENIKNQMLE
                     KLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGL
                     NFIS"
     gene            34630..36921
                     /gene="opgB"
                     /locus_tag="ACHY1N_002808"
     CDS             34630..36921
                     /gene="opgB"
                     /locus_tag="ACHY1N_002808"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HFS4045097.1"
                     /translation="MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNIT
                     LFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRR
                     HHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDP
                     KLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIAAFINKIKASPWFKDTVIVLS
                     SDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNY
                     LGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELA
                     LSTDWCVSQGQLGGQQIVQHVDKTTWQGKTAFKDTVIDMARYKGNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITA
                     KAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVEREG"
     gene            complement(37061..38083)
                     /gene="lgoD"
                     /locus_tag="ACHY1N_002809"
     CDS             complement(37061..38083)
                     /gene="lgoD"
                     /locus_tag="ACHY1N_002809"
                     /EC_number="1.1.1.414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418778.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-galactonate oxidoreductase"
                     /protein_id="HFS4045098.1"
                     /translation="MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDI
                     HAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGR
                     TNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
                     APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPLLDPSAEDF
                     DAQLRAQFGGSLAQKVIDATGNQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHK
                     KETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYQFATLAETYERDVINNRELI
                     KGVITF"
     gene            38222..39136
                     /gene="lgoR"
                     /locus_tag="ACHY1N_002810"
     CDS             38222..39136
                     /gene="lgoR"
                     /locus_tag="ACHY1N_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313344.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FCD domain-containing protein"
                     /protein_id="HFS4045099.1"
                     /translation="MSRSQNLRHNVINQVIDDMARGHIPSPLPSQSALAEMYNISRTT
                     VRHILSHLRECGVLTQVGNDYVIARKPDHDDGFACTTASMSEQNKVFEQAFFTMINQR
                     QLRPGETFSELQLARAAGVSPVVVREYLLKFGRYNLIQSEKRGQWSMKQFDQSYAEQL
                     FELREMLETHSLQHFLNLPDHDPRWLQAKTMLERHRLLRDNIGNSFRMFSQLDRDFHS
                     LLLSAADNIFFDQSLEIISVIFHFHYQWDESDLKQRNIIAVDEHMTILSALICRSDLD
                     ATLALRNHLNSAKQSMIRSINENTRYAH"
     gene            39351..40712
                     /gene="lgoT"
                     /locus_tag="ACHY1N_002811"
     CDS             39351..40712
                     /gene="lgoT"
                     /locus_tag="ACHY1N_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4045100.1"
                     /translation="MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAM
                     LLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLD
                     RKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
                     IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYR
                     NREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLY
                     LAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKIC
                     IIAGMFCSAAFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASV
                     GSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDP
                     RKD"
     gene            complement(40761..42425)
                     /gene="tsr"
                     /locus_tag="ACHY1N_002812"
     CDS             complement(40761..42425)
                     /gene="tsr"
                     /locus_tag="ACHY1N_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004888 - transmembrane signaling receptor
                     activity [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HFS4045101.1"
                     /translation="MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQ
                     TIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVAELMQSASISLKQAE
                     KNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
                     DGFEKQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASL
                     VAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANA
                     IYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSAS
                     ETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQ
                     GRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVT
                     RVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRL
                     TEAVAVFRIQQQQQQQRETSAVVKTVTPAAPRKMAVADSEENWETF"
     gene            complement(42544..42990)
                     /gene="hpaR"
                     /locus_tag="ACHY1N_002813"
     CDS             complement(42544..42990)
                     /gene="hpaR"
                     /locus_tag="ACHY1N_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoprotocatechuate degradation operon regulator
                     HpaR"
                     /protein_id="HFS4045102.1"
                     /translation="MHDSLTIALLQAREAAMSYFRPIVKRHNLTEQQWRIVRILAESP
                     SMDFHDLAYRACILRPSLTGILTRMERDGLVLRLKPINDQRKLYISLTKEGQALYNRA
                     QTQIEEAYRQIEAQFTAEKMQQLTHLLEEFIALGNSRQEDIPGDNE"
BASE COUNT        10223 a        11622 c        10855 g        10351 t
ORIGIN      
        1 aaaacagcaa aaaatgctat tatccaatta cctgatgtca ggtgctcgtt gttgaaagga
       61 tgaggatatt ttatggatca ggccggcatt attcgcgacc ttttaatctg gctggaaggt
      121 catctggatc agcccctgtc gctcgacaat gtagcggcga aagcaggtta ttccaagtgg
      181 cacttacaga gaatgtttaa agatgtcact ggccatgcta ttggcgcgta tattcgtgct
      241 cgtcgtttgt cgaaatcggc ggtcgcacta cgcctgactg cgcgtccgat tctggacatc
      301 gcgctgcaat accgcttcga ctctcaacag acatttaccc gcgcattcaa gaagcagttt
      361 gcccagactc ctgcacttta ccgccgttct cctgaatgga gcgcctttgg tattcgcccg
      421 ccgctacgtc tgggtgaatt cacaatgcca gagcacaaat ttgtcaccct ggaagatacg
      481 ccgctgattg gtgttaccca gagctactcc tgttcgctgg agcaaatctc tgatttccgc
      541 catgaaatgc gttatcagtt ctggcacgat tttctcggca acgcgccgac cattccgcca
      601 gtgctctacg gcctgaatga aacgcgtccg agtcaggata aagacgacga acaagaggta
      661 ttctatacca ctgcgttagc ccaggatcag gcagatggct atgtactgac ggggcatccg
      721 gtgatgctgc agggcggcga atatgtgatg tttacctatg aaggtctggg aaccggcgtg
      781 caggagttta tcctgacagt atacggaacg tgcatgccaa tgctcaatct gacgcgccgt
      841 aaaggtcagg atattgagcg atactacccg gcagaagatg ccaaagcggg agatcgccca
      901 attaatctgc gctgtgaact gctgattccg atccgtcgtt aacgctgcaa ctcatctaat
      961 gcaggggcgt ccagatgcga gatgtcccct gcggtttcaa caacccagcc agacgccagc
     1021 cacaggcttt cctgataatc cacgcgcgaa atagaacagt tacgcagacg taagcggcgc
     1081 tctgcccatg ctggtaatcc gagaatcgta ctcaccagac atcccagtgc aataccatgg
     1141 ctcaccagca gcggtcggct tccctgcggt aagtcccggc aagattccag tgccgcattg
     1201 acgcgatcgc tgagctcctg cattgactcg ccttcaggaa tacgcccgtc aacggtgcca
     1261 ttgaccagct gccgacgcca gttctcttct tcttcggtca gagaatcgat atgtcttttt
     1321 tccagcacac ccatgtttaa ttcacgcagg cgagaatcaa agatgatgtc acagccgcag
     1381 gcctgggcga tgatttccgc cgtacgccgg gtgcgtccta aatcgctact gatgatatgc
     1441 gtaatgccaa gctctttggc acgggttgcc acctgcatcg cctgttgctc acctttggcg
     1501 gtcagcgggc tgtcagactg gccctgaata cgtcgctcgg cgttccactg cgtttcaccg
     1561 tggcggacta ggtatacctg taacatgctt tttttccgta tactgctgta acgttaattt
     1621 tctgagtaat gctgattatg caccaagttg tctgtgcgac caccaatccc gctaaaattc
     1681 agtccattct gcaggcattt cacgagatct tcggcgaagg atcctgccat attgcatccg
     1741 ttgccgtcga gagcggtgta ccggaacaac cctttggcag tgaggaaacg cgcgctggcg
     1801 cacgaaatcg ggtagcaaat gcccgccgtt tacttccaga ggctgatttt tgggtggcga
     1861 ttgaagctgg catcgatggt gacagcactt tcagttgggt ggtgattgaa aacgccagcc
     1921 agcgcggcga ggcgcgttcg gctactttgc cgttgcctgc ggtgattctg gaaaaagtgc
     1981 gtgaaggtga ggcacttggt cccgtgatgt cgcgttatac cggtattgat gagattggtc
     2041 gtaaggaagg ggcgatcggc gtgtttaccg ccgggaaact cactcgcgcc agcgtctatc
     2101 accaggcggt gatcctggcg ctgagtccgt ttcataatgc ggtgtatcag gcattgtagg
     2161 acggataagg cgttcacgcc gcatccggca ttcggtgcac gatgcctgat gcgacgctgc
     2221 cgcgtcttat caggcctaca aaatcaatcg cttttcagca acacctcttc cagccactgg
     2281 cgcagctcaa cgggcgcggc tttcaggctg ttagatccac gcgtaatcgt cgcgatgccc
     2341 gcgccgagtt cattttttaa ctcacgctgg ctcatttcgc cgcgcaacag ctcttcgaca
     2401 atacgcacgc gagtccccaa cgcttcgcgc tcatctggcg tcagcatcag gtttaacaac
     2461 ggtaaatgga gatcgttttg gtaggcattc ttaagcaggt cgacaaaacg taaccactct
     2521 tggtgacgct gttctgccat cgctgctgaa tagggtgatt gttgggccat aatatgtcgc
     2581 cattgttagc gggggaagca aaatgcctcc cccggttgta ctcgctaaag agtacgatag
     2641 catatcataa acgtgcggat cagtaacgac gtccccattc cgtggcgctc atcaacgtcg
     2701 gtttatcccc catgaaatag cggtagtaag cgtcataagc cagcacgttc ttcacataac
     2761 cgcgcgtctc ggagaacgga atactctcga caaatgccac agcgtcgata cgcccggcgc
     2821 tgttgccaag ccaggttcgc acccgtccag gtccggcgtt ataagctgct gaggagaaaa
     2881 tacggttatt gccaaactgc tgataaacat attgcaggta actggtgcca atgttgatgt
     2941 tcgtttccgg atccagcaat tgcccagggc tgctataacc aggaatagag aacatcttca
     3001 ccgtatgggt cgctgtacca ggcataatct gcatcaggcc gctggcccct accggtgatt
     3061 tcactttcgg attccaggcg ctctcctgac gggcaatcgc catcgcatag ctttgcggga
     3121 tctccttacc gctggtgtag cgtttgaaaa gatcgttgta agccagcggg aatcgctctt
     3181 ccagatgatc ccacagcttc ccggcgatcg ttgcctgaac gctaagatcc caccattggt
     3241 tgttgaaagc ataccgcgcc agttgagcct gctctgtttt tgacttgctc ttcaccagat
     3301 tggcccactc gctacgcgcg gtgttatcga gattccagta catcaactcg cgcacgcgcg
     3361 ccatctccgg cccctgagtc agggcgctgt caacattctg cggcgcttta tcaatcttca
     3421 gctcatactc ttcgccgatg cgttgtgcag caaccatcgg gtagaaacca cgctgttgca
     3481 tgagttgatg caaaatctct ttcgcttcag cttcacgtcc gcgttccagc aataaatccg
     3541 cctgccagta acgccattca tctttctctt ttgcttccat cggcagacgc gccagccagg
     3601 tattcaggcc gcgacgatcg ccggtgccaa gcgccattcg cacacggcgt tcaatcaacg
     3661 acgtggattg cgagcgcata atggcgtcat cgcgccattt cgcctgctcg tcggtgacat
     3721 cgttgcccat caaacgccag gcgacgatat cgcgcagctc ctgaatctga tcttcattaa
     3781 gctgctgcgc ctgggcaagc gacgggatca tcagccgtgc attttcagca tcctgccgcg
     3841 ccacactggc aaacgccacc gccgccattt gacgggtaaa atcggtcgcg ccggttgtac
     3901 gcgcgaaggt cagtaccgta ttagggttgt tcgccagtga aatgattgcc gaggcgatag
     3961 tctggtaatc ggcaggcatc tgccctgcca gcactgttac caggccagtg ttacccgctt
     4021 tcatcgccag gcggatacgc tctaaatacg ccagcggatc ttgtttacct gacgcacgcc
     4081 agacgctaaa taacttgtca caggcgttag gctggctctt gccggttagc cacagctctt
     4141 tcgccccttg ccaggcttct tcactctgcc cggtgttcca tttcgcatag tagtaattac
     4201 attgcgcttc ggtagttccg ggcttttccg ggctaaaggc taacaagcca cgccagtctt
     4261 cacgccgcgc cagttcattg acgaaacgag attgcagcgt gcgagcggga ggaagcgtgg
     4321 ggttagcgcg aacaaagtta gtgaccgtca ccgccggttg attcatcagg tcatcggtga
     4381 tctggcggta ttccaggtag ggataaagcg gataatcctt cagtccaggc atcatttgtt
     4441 cgaccacatc catttgtcga ttatcccagg cctgcttgat ttgcgcgtaa cgactacgct
     4501 gctcatccag tgagtcggct cgcgccacgc tgctgaccgt cagcagacag acaccggcag
     4561 ccaacagccg ccaggtaact tgtttggctt tttccacaag cgcatcctct aagtgtaaat
     4621 acatcaatgc agcgtcatgc cgcgtaatag atttatgcta accagtcatt gccgtttacg
     4681 ccacgttacg gacacttttt tacttttact gcgaaggtga tcgaccaact gggattaggc
     4741 ggggaaaaag gctacacttc gcctttgaaa actcatcatc acgataaaca tagaggcgaa
     4801 gtccaacgtg gctcaattcg tttataccat gcatcgtgtc ggcaaagttg ttccgccgaa
     4861 acgtcatatt ttgaaaaaca tctctctgag tttcttccct ggggcaaaaa ttggtgtcct
     4921 gggtctgaac ggcgcgggta agtccaccct gctgcgcatt atggcgggca ttgataaaga
     4981 catcgaaggt gaagcgcgtc cgcagccaga catcaagatt ggttatctgc cgcaggaacc
     5041 gcagctgaac ccggaacaca ccgtgcgtga gtctattgaa gaagcggttt ctgaagtggt
     5101 taacgccctg aaacgcctgg atgaagtgta tgcgctgtac gccgatccgg atgccgattt
     5161 tgacaagctg gccgctgaac aaggccgtct ggaagagatt attcaggctc acgacggtca
     5221 taatctgaac gtacagctgg agcgtgcggc ggatgcgcta cgtctgccgg actgggacgc
     5281 gaaaatcgct aacctctccg gtggtgagcg tcgtcgcgtg gcgttgtgcc gcctgctgct
     5341 ggaaaaacca gacatgctgc tgctcgacga accgaccaac cacctggatg ccgaatccgt
     5401 ggcctggctg gaacgcttcc tgcacgactt cgaaggcacc gtggtggcga ttactcacga
     5461 ccgttacttc ctcgataacg ttgcaggctg gatcctcgaa ctggaccgcg gtgaaggtat
     5521 tccgtgggaa ggtaactact cctcctggct ggagcagaaa gatcagcgtc tggcgcagga
     5581 agcttcacaa gaagcggcgc gtcgtaagtc gatcgagaaa gagctggagt gggtacgtca
     5641 gggaactaaa ggccgtcagt cgaaaggtaa agcacgtctg gcacgctttg aagagctgaa
     5701 cagcaccgaa taccagaaac gtaacgaaac caacgaactg tttattccac ctggaccgcg
     5761 tctgggcgat aaagtgctgg aagtcagcaa cctgcgtaaa tcctacggcg atcgcctgct
     5821 gattgatgac ctgagcttct cgatcccgaa aggggcgatc gtcgggatca tcggtccgaa
     5881 cggcgcgggt aaatcgaccc tgttccgtat gatctccggt caggaacagc cggacagcgg
     5941 caccatcact ttgggtgaaa cggtgaaact ggcatcggtt gatcagttcc gtgactcaat
     6001 ggataacagc aaaaccgttt gggaagaagt ttccggcggg ctggatatta tgaagatcgg
     6061 caacaccgag atgccaagcc gcgcctacgt tggccgcttt aactttaaag gggttgatca
     6121 gggtaaacgc gttggtgaac tttccggtgg tgagcgcggt cgtctgcatc tggcgaagct
     6181 gctgcaggtt ggcggcaaca tgctgctgct cgacgaacca accaacgacc tggatatcga
     6241 aaccctgcgc gcgctggaaa acgccctgct ggagttcccg ggctgtgcga tggttatctc
     6301 gcacgaccgt tggttcctcg accgtatcgc cacgcacatc ctggactacc aggatgaagg
     6361 taaagttgag ttcttcgaag gtaactttac cgaatacgaa gagtacaaaa aacgcacgct
     6421 gggcgcagac gcgctggagc cgaagcgtat caagtacaag cgtattgcga agtaatgcgt
     6481 aaaatgccgg atgcggcgtg aacgccttat ccggcctaca aaccaagaaa tttcaatacg
     6541 ttgtgaatct ccaggcctga taagacgcgg taagcgtcgc atcaggcatt gagcaccgaa
     6601 tgccggatac ggcgtgaacg ccttttccgg cctacaacag ccttagtatc cgcaaattcg
     6661 tagcgggtca cccgtgctga ttcttttaaa ccttgtttaa tctcgacagc ctcttccaga
     6721 gaggttttca actcatcaaa aaacttattt tatacctcgc ctttgagccg tttcatcgcg
     6781 gttatctctg ctcccccatc atctcccgca ccagctccac gcagcgcagg aaacggctgt
     6841 cataatcgtc ctcttcaacc cgcacgaatt cgatattgtt ctcttccagc atctccacca
     6901 gcaagttctg gaactctttg cgatccaccg aactgccgag gctgcgtaaa ccatccgcca
     6961 cccacggcgt gttgttctcc agcaggatca ccagatcgaa acggtattca tcaatcaacg
     7021 cctgtacgaa cggatgctca cgcccttcgt actttttgca gaacgcctgg gtagtgacaa
     7081 aatcagtgtc aataaacgcc actttattgg catatttcac tgcaaaatca atgtattgtg
     7141 cgtggcccag cgcgatttta tcgtaatcgg aatactgcaa tgcgatctca tcaccgccga
     7201 ggtgtgaaaa gacataatcg cgaccatatt cccacgcact ggtggtattg aagatattgg
     7261 caagtttgtt taccagggtg gatttaccgc tcgactcgcc accaaggatc gccacggtac
     7321 gtacaaagaa cggcttcact tccgtaggaa tatattccca gtagcggaac gggttttcgc
     7381 ggatctgcgc accgctgata ctcataaagg tacgtttcgg atcgaccagc accgtatcga
     7441 tccccagatg ttccatatac tgtggcgcat cggcttcttc cgaggtgtag atcaggtccg
     7501 gctgaatccc cttttcagcc ataaactttt tgatgccgtt gctccacaca tcccagccgt
     7561 gcggatacgg ctccatgccc tcttcgttga aagcatgaat gcgaatattt ttctgatatt
     7621 taaaagtttg taataaccag cgcagacgat ccggcaccgt gggctgctgc gacatggcgc
     7681 tgtcttcaaa caacgcgcgg tcgcgggtat cgtcaaaacc cataatgata tgcagctcgt
     7741 caacctggct acaggcgcgc tggataaggt agatatgtcc ggtatgcagc gggtagaact
     7801 taccgaatac gacaccaatg gttttcttct gtcggggaaa ttcaagcccc aaaaaacggt
     7861 gcaacgcctc cagcttttgc gcgctggggc ttttaatttt ggcattcagt aactggctta
     7921 aatacccttt ggtcataccg ctggcatcag ctacctgctg tagcgtgcag ccctgttgct
     7981 tgatggcagt tttcaggtaa tcaaatgacg acatatctcc ctccgtatct ctcattataa
     8041 gtcgtcgaac acgctaagcg cgtcggagag ttttttaacg ccaaaaatct gcatcccttc
     8101 cggcgctttt ttcggtacgt tagccgccgg aacaatcgcc cggcgaaaac cgtgtttcgc
     8161 cgcttctgaa attcgttcct gaccgctggg caccgggcgg atctcccctg ccagcccgac
     8221 ttcaccaaac accaccagat cctgtggcag cggtctgtca cgcaggctgg aaaccatcgc
     8281 cagcagtaac gctaaatcgg cactggtttc ggttaccttc acgccgccga ccacgttcac
     8341 aaatacatcc tgatcggcca tttgcagacc accgtgacgg tgcaagacag ccagcaggat
     8401 tgccagacgg ttttgttcca gccccactgc cacgcggcgc ggattcgcca tcatcgagtg
     8461 atcgaccagc gcctgaatct ccaccagcaa cggacgcgtt ccttcccaca ccaccatcac
     8521 ggagctgccg gaggtcactt catctccgcg acttaagaaa attgccgaag ggttgctgac
     8581 ttcacgcagc ccctgttcgg tcatcgcgaa gacgcccagc tcattcaccg cgccgaagcg
     8641 gtttttatgg ctgcgcaagg tgcgaaaacg ggagtcggca tcaccatcca gaagcaccga
     8701 acagtcgata cagtgttcca gcactttagg gccagccagc gagccatctt tggttacgtg
     8761 cccaaccatg acaatcgcca caccgcgcgt tttggcgaag cgcgtcagat aagccgccgt
     8821 ttcacgcacc tgcgccacgc taccaggcga tgattgtaca tccgccatat gcatcacctg
     8881 gatcgagtca attaccatca gtttcggttg ctcttcttcg gcaatcaggc agatctgttc
     8941 gatgctggtt tccgacaaca tattgagatt gtcagtcggc aggccaaggc gatgagcgcg
     9001 cattgccacc tgttgcagcg actcttcgcc agtgacatac agcgttttca tctgctgggc
     9061 cagtttgcac agcgtttgca gtagcagcgt ggatttcccc gcacctgggt taccgccaat
     9121 cagaatggcg cttcctggca ccacgccgcc gcctagtacg cggtcgaact ctttaaatcc
     9181 ggtggaaaaa cgcggcagct cttcaaggct gatatcggag agtttctgga cttttgccac
     9241 cccggcgcta ccggcatagc cgctgagacg ctcgttacgc gccaccgttg gcgacgcagc
     9301 aagacgcacc tcggtgatgg tgttccaggc atgacaggca ctgcactgcc cctgccagcg
     9361 cggataatcg gccccgcatt cattacaaac aaaggcgcgt tttggagctt ttgccacggt
     9421 gtacctcgtt aatgctgtgc cgcccgcagg atggcgggcg agcaattact tctgattcag
     9481 gctgccagag aggatgcaga atacccccat caggtcagcg tgacggatgg tgacttccgc
     9541 cttttcattc acttttggct tggcatggta ggcaatcccc agccctgctg ctttgatcat
     9601 cggcaggtca ttagctccat cgccaatcgc cacggtctgc gccagcggga tttcatactc
     9661 ctgcgcgagg cgagtcaaag ttttcgcttt gtactgcgcg tctacgatgt cgccgatcac
     9721 attgccggta aatttaccgt ccatgatctc cagttcattg gctaccacgg cggtcaggcg
     9781 cagcttgtcg cgcagatatt cagcaaagaa agtaaagccg ccggaggcaa tcgccacttt
     9841 ccagcccagc gtttccagct tgagcaccag ttgcgttaag cctggcatca gcggcagatt
     9901 ttcacgcacc tgttgcagaa tattggcgtc agcgcctttc agcgtcgcca cacggctgtg
     9961 caggctggcg gtaaaatcga gttcgccgcg catcgcccgt tcggttactt ccgccaccat
    10021 ctcgcccgtt ccggccagtt tggcaatttc atcaatacat tcaatctgga tggcggtgga
    10081 atccatgtcc atcaccagca aacccggcgt gcgcaggtgc gggattttcc ccagcggggc
    10141 gacatccagt tgcgcttcat gggccaggcg cgtagcccgt gcggtgagtg aacctgccag
    10201 acgaatcacc tgataatctt ccacgcacca ggcggcaaca atcaccatcg ccgcacccag
    10261 tttgctctgg tattgggtca gacgctgttt atccagccca cgaccataca gcagccagcc
    10321 gctacgacct gcgtggtaat ccagtggcat cacttcatca ccacttaatg aaagaggcag
    10381 accaggccat aaagagacat cttcaggcag gtcgcaccag gtaatgttag gcattaaggc
    10441 tcctgtaaaa tcgttcgaag cagggaaaat aacgcatgag gctaccttgt atccattgct
    10501 tctggcaaca ttaagtctca aattttcaaa gggtggaaga tggctcgcac aaaactgaaa
    10561 ttccggctgc atcgggcagt gattgtcctg ttctgtcttg ccttgttagt ggcgctgatg
    10621 cagggagcgt catggtttag tcaaaaccac cagcgacaac gtaatccaca gctggaagaa
    10681 ctggcccgca ccctggcgcg tcaggtaacg ctgaacgttg caccgctgat gcgtaccgac
    10741 tcaccggatg aaaaacgcat tcaggcgatc ctcgatcagt taacggatga aagccgtatc
    10801 ctcgacgcgg gtgtgtatga cgaacaaggc gatcttatcg cacgttctgg cgaaagcgtc
    10861 gaagtgcgcg accggctggc gctcgacggt aaaaaagcgg gcggctattt taaccagcag
    10921 attgtcgaac caattgccgg gaaaaacgga ccgctcggct atctgcgcct gacgctcgac
    10981 acccatacgc tcgccaccga agcccaacag gtggataaca ccactaacat tttacgcctg
    11041 atgttgctgc tttcactggc aatcggcgta gtgctgaccc gcacgctgct acagggtaaa
    11101 cgtacccgct ggcagcaatc gcccttcctg ttaaccgcca gcaaaccggt gccggaagag
    11161 gaagaaagcg agaaaaaaga gtgacccatt actacaagaa aggaaatcgt tatgtccaca
    11221 ttacgcctgc tcatctctga ctcttacgac ccgtggttta acctggcggt ggaggagtgt
    11281 atttttcgcc agatgcccgc cacgcagcgc gttctgtttc tctggcgcaa tgccgacacg
    11341 gtagtgattg gtcgcgcgca gaacccgtgg aaagagtgta atacccggcg gatggaagaa
    11401 gataacgtcc gcctggcacg gcgcagtagc ggtggcggcg cggtgttcca cgatctcggc
    11461 aatacctgct ttacctttat ggctggcaag ccggagtacg ataaaaccat ctccacgtcg
    11521 attgtgctca atgcgctgaa cgcgcttggc gtcagcgccg aagcgtccgg gcgtaacgat
    11581 ctggtggtga aaaccgccga aggtgaccgc aaagtctcag gatcggccta tcgcgaaacc
    11641 aaagatcgtg gcttccacca cggcaccttg ctgctcaatg ccgaccttag ccgcctggca
    11701 aactatctca atccggataa aaagaaactg gcggcgaaag gcattacctc agtgcgttcc
    11761 cgcgtgacca acctcaccga gctgctgccg gggatcaccc atgagcaggt ttgcgaggcc
    11821 ataaccaagg cctttttcgc ccattatggc gagcgtgtag aagcggaaat catctccccg
    11881 gacaaaacgc cagacttgcc aaacttcgcc gaaacctttg cccgtcagag tagctgggaa
    11941 tggaacttcg gtcaggctcc ggcattctcg catctgctgg atgaacgctt tagctggggc
    12001 ggcgtggaac tgcatttcga cgttgaaaaa ggccatatca cccgcgccca ggtgtttacc
    12061 gacagcctca accccgcgcc gctggaagcc ctcgccgggc gactgcaagg cggcctgtac
    12121 cgcgcggata tgctgcaaca agagtgcgaa gcgctgttgg ttgacttccc ggaccaggaa
    12181 aaagagctac gggagttgtc gacgtggata gcgggggcgg taaggtaact cgctgattaa
    12241 aataccaaag gaagggaata tgatcgatct ggaaaaccag gagcgggaga ttatcaatat
    12301 aatgttaagc cagcgtattt cctggctagc cgccgtgcgt atcaggcata aattatcgct
    12361 tgctgaagta agtaaaatgt taggtatctc gattaattct ctaaaataga tcgaaaagac
    12421 ggaacggttt agctcaaaca tcaaaagcaa aatggcagaa atttatggtt gtccaccaga
    12481 gttgctgata tgcccttcct ggatgacggc tgaacataaa tgaatagatt cgtgaataga
    12541 tacttgaata gattttattt tctatccata tgaaaaataa tagtaaatct ataaatcagt
    12601 tgctattgat gaatagatac taaaaagccg gagcagtctc ccactccggc ttcacacgac
    12661 aatcgccttt cagcgaaaca caattactct ttatcgccca gcagaacgga ttccagtgcg
    12721 attttgatca tgtcgttgaa ggtggtctga cgctcagcgg cagtggtctg ctcgtgagtg
    12781 cggatgtggt cagacacggt acagatggtc agggctttcg cgccaaattc tgcagcgacg
    12841 ccgtagatac cagccgcttc catttccacg ccgaggatgc cgtatttttc catcacgtcg
    12901 aacatttcgc cgtccggaga gtagaacagg tcagcggaga acaggttacc aacgcgagca
    12961 tcaatgccca gtgctttagc cgcgtctacc gcgttacgca ccatgtcaaa gtcagcgata
    13021 gcggcaaagt catgatcttt aaaacggatg cggttaactt tggaatcggt gcaggcaccc
    13081 ataccgataa cgacgtcgcg cagttttacg tgcggcagaa ctgcgccaca ggaacccacg
    13141 cggataattt tcttcacgcc gaaatcggtg atcagttctt tggtgtagat ggagcaggac
    13201 gggataccca taccgtgacc cattacggaa attttgcggc ctttataagt accggtgaag
    13261 cccagcatac cgcgaacgtt gttcacttca cgggcatctt caaggaaagt ttcagcaata
    13321 tactttgcac gcagcgggtc gcctggcatc aaaactacgt cagcgaaatc gcccatttct
    13381 gcattaatgt gtggggtagc cattgtttta tccttatcta catgttttca ccctctccct
    13441 gagggagagg gccggggtga gggcatcaag ccgcacccat tatcagaaca tggctttgcc
    13501 atattccata tcagaagtac caaaatattt tgccagagtc tggccgatat ccgcgaaggt
    13561 ttcacggtga cccagtgagc ccggttttac tttcgggccg taaaccagta ccggaatgtg
    13621 ttcacgcgtg tgatcagtac cggtccaggt cggatcacaa ccgtggtcag cagtgaggat
    13681 caggatgtcg tcatcgcgca gcagagacat cagctccggc agacggcggt cgaacagttc
    13741 cagacccgcc gcataacctg cgacgtcgcg acggtggccc caggaagagt cgaagtcaac
    13801 gaagttggtg aagacgatgg tgttatcacc cgcttctttc atctctttga tggtggcgtc
    13861 aaacagcgcg tccaggccag ttgctttcac tttcttggtg ataccgcagt tggcgtagat
    13921 gtctgcaatt ttaccgacag aaaccacctg accgtgtttt tcatcaacca gtttctgcag
    13981 cacggtcggt gctggcggct caacagccag gtcgtgacgg ttaccggtac gctggaagtt
    14041 accggctttg tcgccaataa acggacgagc gataacacga ccgatgttgt agccgccgtt
    14101 ggtcagctct tcacgggcga tttcgcacag ttcgtagagt ttatccaagc caaaggtttc
    14161 ttcgtggcag gcaatctgga acacggagtc agcggaggta tagaaaatcg gcttgccggt
    14221 tttcatgtgc tcttcgccca gctgatccag aatgaccgta ccggaagagt ggcagttacc
    14281 gagataacca ggcaggttag cgcgttcaac cagtttatcc agcagctctt gcgggaagct
    14341 gttttcgtga tcggagaagt atccccactc aaacagaacc gggacaccgg cgatttccca
    14401 gtgaccagac ggggtatctt taccggatga catttcgtgc gcccatgcgt acgcgccgat
    14461 aacttcagcg ttgccgtcca ttcctgccgg aatgaaaccg gtagaacctt catgtgcttt
    14521 cgccagcccc agacgggtca gatttggcag attgagcggg cctttacgac cgttatcagc
    14581 ttcgcctttg gcacaggctt ctgcgatatg acccagggtg tcagccccga cgtcaccaaa
    14641 gcgttctgca tcttctgtag cgccgatgcc gaatgagtcc agcaccataa taaatgcacg
    14701 tttcatatgt tctccgtact cagtgcttca aatttaaatg atcagatcag tataccgtta
    14761 ttcgctgata cggcgataga cagttggtgt gctttccggt gctttatcgg caagtttaat
    14821 tgccgctttc accgctttcg ccgcgtcctg ccagctgttt tcgtctttcg cgtggataac
    14881 agccagcgga cgctgaccgt ctacctggtc gcccaaacgc gccatatcag taaagccgac
    14941 gctgtaatca atggtgtcag atgcctgacg acgaccgccg cccattgcaa ccactgccat
    15001 ccccagcgcg cgggtatcca tttcactgac aaaaccttcg gtatcagcat agactgcttt
    15061 cgtcagcatc gctgtcggca gatacttcgc gtagttctca acgaagtcgg ttgggccttt
    15121 ttgtgccgct accatacgac caaagacttc tgccgcttta ccgttgtcca gcactgcttg
    15181 caatttcgcg cgcgcttcgg cgtcatcttt cgccagtttg ccggagataa gcatctccac
    15241 gcacagtgcc atcgtgacat caaacagacg cgggttacga tattcacccg tcaggaactg
    15301 caccgcttca cgaacttcaa ccgcgttacc tgcactggag gccagtacct gattcatgtc
    15361 ggtgagcagc gcggtggtgc gcacgccagc gccgttagcc acgccaacaa tcgcttcggc
    15421 aagggcttca gagagttcgt aggtcggcat aaacgcgccg ctacccactt tcacgtccat
    15481 caccagcgca tccagacctt ccgccagttt cttcgccagg atcgaggcag tgatcagcgg
    15541 gatggagtcc acggttgcgg taatatcgcg ggtcgcgtag aaacgtttat ctgccggagc
    15601 caatgagctg gtctggccga taatcgccac gccgacgtct ttaataattt cgcggaaacg
    15661 gttgtcatcc gggaaaatgt cgaagccagg gatggattcc agtttgtcga gcgtaccgcc
    15721 agtatgaccg aggccgcgac cagagatcat cggaatatag ccgccgcagg ctgcgaccat
    15781 cggccccaac atcagcgaag tcacatcgcc gacgccgccg gtcgagtgtt tatcaacaat
    15841 cgggccattc agatgcaggc ttttccagtc gagaacggtt cctgaatctc gcatcgccat
    15901 ggtcagcgag acacgctcag gcattgtcat atcgtggaag aaaatggtca tcgcgagggc
    15961 ggcaatctgc ccttcggaga tagtgttgtc gcgaataccg ttgataaaga aacgaatttc
    16021 ttcatcgctc agcgcatgac catcacgttt tttacgaata atttcttgtg cgagaaacaa
    16081 ggtaacctcc cgaggaaaag agtatgaggc ggcttttgcc ggatgcgtct acgccttatc
    16141 cggcctacgg gtagatacgt ctcgtaggcc tgataagcgc agcgcatcag gcgtaaagca
    16201 tcttacttag tagctgctgg cgctcttacc gtcgccgtgg cccagagcct tcagcaggct
    16261 tgccagcagg ctggaagcac caaagcggta gtggcgcgca tcggcccagt cagcgccgaa
    16321 cagttcatct gcgatggcga gatatttctg cgcatcttcc gcagtacgca cgccgcccgc
    16381 cggtttgaaa ccaacggttt tttctacgcc catatcacga atcacttcca tcatgatgcg
    16441 cgcgctttcc ggcgtcgcgt tcactgccac tttaccggta gaggttttga tgaagtcagc
    16501 acccgctttg atggagattt cagacgcttt acggatcagc gcttcgtctt tcagttcgcc
    16561 ggtttcgatg atcactttca gcagtacatt cgctgccgcg caagcctctt tacaggcttt
    16621 caccaggtca aaaccaacct gctcgttacc cgccatcagc gcacggtacg ggaacaccac
    16681 gtcaacttca tcggcaccgt aggcgattgc cgcacgggtt tctgccagcg cgatttcgat
    16741 gtcgtcgtta ccgtgtggga agttagttac cgtagcaata cggatttccg gggtgccctg
    16801 ctctttcagc gttttgcgag caatcgggat aaagcgagga tagatacaga tagcggcggt
    16861 attgccgacc ggagttttgg cctgatgaca cagagcaatt actttctcgt cggtgtcgtc
    16921 gtcattcagg gtggtcaggt ccatcaattt cagtgcacgc aggctgcttg ctttcagatc
    16981 agtcatttca ttctcctggc ttgtcgccaa taaaattcac cttgcgagtt tgttagtatt
    17041 ctaacatcta ctccgcaaca cacttcgata tacatcacaa ttaaggaaat ctacttacaa
    17101 gtttgcatca ctgtaatgcg atctggttca aataattcac tttcaaatga atgcgtcagt
    17161 ggtggcaaac gcatcaggat caaagtgaac atcacgaaac ttcttacaat ggcgcatcac
    17221 cttcggcata aaaggaaaag aagatgccca cttctcatga aaatgcactg caacaacgtt
    17281 gccagcaaat tgtcaccagc ccagtgctta gcccggagca gaagcgccat tttctggctc
    17341 tggaagcaga aaacaatctg ccttatccgc agcttcctgc cgaagcccgc cgcgcgctgg
    17401 atgagggtgt aatctgcgat atgtttgaag gtcatgcgcc gtacaaaccg cgctatgtct
    17461 tacccgatta cgcccgtttt ctggcgaacg gttccgaatg gctggagctg gaaggcgcga
    17521 aagatcttga tgacgcactc tctctgctga ccattcttta ccaccacgta ccgtcggtca
    17581 catcgatgcc ggtctacctg gggcaactgg atgcgttgtt gcaaccgcat gttagaattc
    17641 taacacaaga cgagatcgat attcgaataa aacgtttctg gcgttacctc gacagaaccc
    17701 tgccagacgc ctttatgcac gccaatatcg gcccgtctga ttcgcccatt acccgcgcga
    17761 tcttacgtgc agacgcagag ttgaagcagg tttcaccgaa cctgaccttt atctacgatc
    17821 ctgaaatcac ccctgatgac ctgctgctgg aagtggcgaa gaacatctgt gaatgtagca
    17881 aaccgcacat cgccaacggt ccggtgcatg ataaaatttt cacaaaaggg ggctacggga
    17941 ttgtgagctg ttacaactca ctgccgctgg cgggtggtgg cagcacgctg gtacgcctta
    18001 acctgaaagc cattgccgag cgcagcgaat cgctggatga cttctttacg cgcactctac
    18061 cgcactactg ccagcagcag atcgccatca tcgatgcgcg gtgtgaattc ctctatcaac
    18121 aatcacactt ctttgagaat agcttcctgg tgaaagaagg gctgattaac cctgaacgtt
    18181 ttgtgccaat gtttggcatg tatgggctgg cggaagcggt taacttgctg tgtgagaaag
    18241 aagggattgc cgcacgttac ggtaaagaag ccgccgcaaa tgaagtgggt tatcgcatca
    18301 gcgcgcaact ggcggagttt gtcgccaata cccccgtgaa atatggctgg caaaaacgcg
    18361 ccatgttaca cgcacagtcg gggatcagtt ccgatatcgg caccacgccg ggcgcgcgtt
    18421 tgccgtatgg cgatgagcca gatccgatca cccatctgca aactgtcgcc ccgcatcatg
    18481 cttattatta ttccggcatc agcgacattc tgaccctcga cgaaaccatc aaacgtaacc
    18541 cgcaggcact ggtacagctt tgcctcggtg cctttaaagc cggaatgcgt gaatttaccg
    18601 ccaatgtcag cggtaacgat ctggttcgcg ttaccggtta tatggtgcgt ttgtcggatt
    18661 tagaaaaata tcgcgccgaa ggttcacgca ccaacaccac ctggctgggc gaagaagccg
    18721 cacgcaacac tcgtattctg gaacgccagc cgcgcgtgat aagccatgaa cagcagatgc
    18781 gctttagtca gtaagattat ccccttctcc tgcgttgacg ggccaggcag tcgtctggct
    18841 ctgtttttgc agggctgcaa tctgcgctgc aaaaactgtc acaatccgtg gacgatggga
    18901 cgttgcaatg actgtgggga gtgcgtgcca cagtgtccgc atcaggcgtt gcagattgtt
    18961 gacggcaaag tggtgtggaa cgctgtggtc tgcgagcaat gtgatacctg cctgaagagg
    19021 tgtccgcaac atgccacgcc gatggcgcaa tccatgagcg tggacgaagt gcttagccat
    19081 gtccgcaaag cggtgctgtt tatcgaaggg ataacggtga gtggcggcga agccacgacc
    19141 cagctgccgt ttgtggtggc gctgtttact gctatcaaaa atgatccgca actgcgccat
    19201 ctcacctgtc tggtggacag taacggtatg ttgagcgaga ccggctggga aaaattgctc
    19261 ccggtgtgcg acggcgcaat gctcgatctc aaagcatggg gtagcgaatg tcatcaacaa
    19321 ataaccggac gcgataatca gcagattaag cgcagcatct gtttgctggc agagcgcggt
    19381 aagctggcgg aactgcgttt gctggtgatc cctggccagg tggattattt gcaacacatc
    19441 gaagaactgg cggcgtttat caagggactc ggcgatgttc cggtacgcct gaacgcgttt
    19501 catgcccacg gcgtgtatgg cgaggcgcaa agctgggcga gcgccacgcc ggaagacgtt
    19561 gagccgttgg ctgatgcgtt aaaggtgcgc ggggtgagcc ggttgatatt tccggcgctc
    19621 tatttgtgac atgccggata cggcctacgg ttcggcacag acttgtaggc atgataagac
    19681 gcgacaagcg tcgcatcagg cattatgcgc cgactgccgg atgcggcgtg aacgccttat
    19741 ccggcctacg gttcggcaca gacttgtagg catgataaga cgcgtcagcg tcgcatcagg
    19801 cattgtgcgc caactgccgg atgcggcgtg aacgccttat ccggcctacg gttcggcaca
    19861 aacctgtagg catgataaga cgcgtcaagc gtcgcatcag gcattgtgcg ccaactgccg
    19921 gatgcggcgt gaacgcctta tccggcctac ggttcggcac aaacctgtag gcatgataag
    19981 acgcgacaag cgtcgcatca ggcattatgc gccgactgcc ggatgctgcc tacgaagggt
    20041 aaactaccca cgaacgctaa acaccgcata cgtattatta agcaacactt cggcaatctc
    20101 atcttctggt tccggacgta actcgcaaag cacgtcaaac acccgcacag cctgttccgg
    20161 gcggttaggc ttcccctgaa agccgttgag cggcatatcc ggcgcgtcgg tttccagcaa
    20221 caacgatgcc agcggtaatt ttgcgatgac atcgcgggtt ttactggcgc gtggataggt
    20281 gatagtaccg cctacgccga ttttgtagcc cagctgtaca aaccgctcgg cctgttgcag
    20341 gctgccggaa aaaccgtgaa ccacgccagt gcgcgataaa tcgtggcgtt taagatgcat
    20401 cgccagtttg tcgtgtgtgc gccgtgaatg caggatcacc ggcagatcgt agcgtttcgc
    20461 cagtttcagc tgttcgtcga gtaaccactg ctgcctctca agttgcggat cgtcgccgaa
    20521 gagatccaga ccgacctccc ccactgccac caccttcgcc ggacgccttt ccagcgcctg
    20581 ctgtagctgc tcaagagaca catcgctatg tttttccaac atacctggat gcaagcccaa
    20641 tgcggcatac agcggttgat atttttccgc taacgcctgc acacgggcaa aattttccgc
    20701 ctctgtcgcc ggaacaatga tcttgcctac gcccgcttgt gccgcgcgtt gcaggctggc
    20761 ctcttcatcg ccactaaacg gcgggaaatc aaaatggcag tgggtgtcga taaaacggca
    20821 aatcaagcca gatcctcatt gttaaatgtc gggtcgttcg cctgcggagc gtcaatcact
    20881 tcggcaacca gcgtatcgtt ggcgactggc gcaggcggaa taacgatcga ttccggcgtc
    20941 accactggca ccagatggcg ggtaagcggc gctttttcag ttaatagctt gccaaccgtg
    21001 gcgaggaaat aacgaccgca taaacgccca agtttatagt cttcacgcag cgccggaatc
    21061 cgactgccaa gcgcgatact atgtaatggc ttcggcggat aaatttcgaa tatccgcagc
    21121 ttgcccggtg gtttctcaat aaattgctga atgtcacgat agctggtttc atgatgctgc
    21181 accagattga ccagcggctg caggctactg tcacccagcc agcgttccat gcgtttgaac
    21241 cactgcggcg tgtagtacat ttgtgacggc acagtgcgaa tgacgaccaa cgttttagcg
    21301 ccctgccttg ccgcctcttt aaccggaatc gcatcactga tcccgccatc caggtagtta
    21361 atgccttcca gcgacactcc gctacgataa aagccaggta tcgcactgga ggcgcgaatc
    21421 acatccagcc agttttgttt ggttggtaaa aagtaattag gcgcgtagtc atcctgacga
    21481 caggcgcaca tataaaacga tttgccgctg tcaaacaacc gcgcggcggt atccatttgc
    21541 aacggcatct ggcttgcggt ggcctccacc agccagtcga gatcgataag atttcctcca
    21601 cggacaaagc gcaatggatc gaaaaattcg cgttttgtgg tatagcgcat gatgactttg
    21661 cgcgcgtaac cgggctgatt gcagataaac gccgagaggt tctgcgcccc ggcagatgtg
    21721 ccgagataaa gatcgaaagg attaaactgc gcgcgcataa actcatccag cacgccagcc
    21781 gtgaaaattc cacgctgtcc gccgccttcg cacaccagag ctattcgtcc aggctggaac
    21841 ggccttagcg acaacggcgc aatattacca agcgttacag gtattcgctg ccccacctct
    21901 gccttcctgt ttttgttgtg aaagaatgac aaagtaacgc aatttattat tcgctaaaac
    21961 cgcaaaagcc agtccgctgg actggctttg gataaaattt tcttaatggt ctgaaatcta
    22021 gggtcgtttt cggcccatga acaaactcac caggaacaga ataatcccga cgacaaagac
    22081 aattttagct gcgcctgcag cggtaccggc cagaccacca aacccaagtg cggcggcgat
    22141 taacgcgata accagaaata tgatgcccca acgaaacata agcgtctcct ttaccatagt
    22201 taatgtcacc gcttgatatg agcgtgaaaa tcactcaatg cgatattttt agtgtggtgc
    22261 acatcgcgcc tcccgacaaa gttcgggagg acgaattacg acgaattact tagttttcag
    22321 atcattttta acgcttttca caccatctac cgctttggcg atactttcag cacggtcgct
    22381 ctgtgcctgg gaatcgacgg taccggagag ctgaaccacg ccgtcggtgg tttcaacttt
    22441 cacatgacgg gaagggacga tatcgtccgc cagcagtttg gctttgattt cactggtggt
    22501 ggcggtgtca cccgcgtagc ccttcacaga gccttcttta gcgtcgcgaa cgtgcagttt
    22561 gtcgctgaca gaggtcaccc cttcaacgcc tttcgccact ttcactgcct cttcggcctg
    22621 agcctggctt tcaacgaaac cgctcagggt cacgactttt tgatcggttt tgacagagat
    22681 atcggtgctc ttgatgttgt catgatccac cagcgccgcc ttcactttcg cggtgatggc
    22741 gctgtcatcc atgaaattac cgactttatt catagagcta tcgacttttt gccctgcgct
    22801 ttcattggta gtctgtgcgt tgttttccgc gtaggcagag ccggtcgcga cggcagaggt
    22861 caacattaca gccagcagag ttttcgaaat cttcagtctt gtcatagtca tcgatttatt
    22921 cctgtatgtt tgctcgtaat ttgagcctgg caacacgagg ttgcattgct gaatagggag
    22981 agacttcacc ctctacagaa gtcaatggtc gccatcacaa aagcgatggg tgatgaataa
    23041 cgaccattac agcctctgaa tcagttatta atatcggtag aatgacaatc gacggcttta
    23101 gatactgata tctacgcatt gaacggtatt taacgccgtc agaaatgtca ttactttgtt
    23161 aaatatagat cacaattttg aaaccgctcg ggatatcagc gaaaacataa gcaaaagtga
    23221 atgttttaag aacattccgt aagcggctaa taaggaaggg aaattgacag ggcgcagcgg
    23281 ctaccgcgcc ctggaggcaa gaattaatgc tcgcgggtct ggtggaactg aacgtcggga
    23341 taacgttcct gcgccaggcg caggttgacc atgctggtag cgatgtaagc gaggttatcg
    23401 ccgccatcaa gcgccagttg gctttcgttc ttacgcttga actcttcgaa tttcttcgcg
    23461 tccgcacatt ctacccagcg ggcagtggca acgttgactg attcatatac tgcttcaacg
    23521 ttgtattcgc tcttcaggcg cgataccacc acatcaaact gcagcacacc aacagcacca
    23581 acgatcaaat cgttgttgga gatcggacgg aacacctgca ccgcgccctc ttcggaaagc
    23641 tgtaccagcc ctttgagcag ctgtttttgc ttcagcggat ctttcaggcg gatacgacgg
    23701 aacagttctg gtgcgaagtt cggaataccg gtgaacttca tcatctcacc ctgggtaaag
    23761 gtgtcgccga tctgaatagt gccgtggttg tgcaggccga ggatatcgcc cggatacgct
    23821 tcttcaacgt gcgaacggtc gcccgccata aaggtcagcg cgtcggagat aaccacatct
    23881 ttcgcagtac gcacctggcg cagcttcatg cctttttcat atttaccgga tactacgcgc
    23941 ataaacgcca cgcggtcgcg gtgtttcggg tccatgttgg cctgaatttt aaatacgaag
    24001 ccggtaaatt tgtcttcgct cgcttgtacg gtacgggtat cagtctgacg cggcatcggc
    24061 gcaggtgccc actccaccag gccatccaac atatgatcga cgccgaagtt acccagcgca
    24121 gtaccgaaga ataccggagt gatttcgccc gcaaggaaca gctctttgtc gaactcgtta
    24181 gacgcgcctt taaccagttc cagttcgtca cgcagctgct gtgccagatc ttcaccaacc
    24241 gcagcatcga gatccgggtt attcagccct ttaacaatgc ggacttcctg aatggtgtgc
    24301 cctttaccgc tctgatagag ataggtttca tctttataaa ggtggtaaac gcctttaaac
    24361 agcttgccgc agccaattgg ccaggtgatc ggtgcgcagc caattttcag ctcgttctca
    24421 acttcatcga gcaattccat cgggtcgcgg atatcacggt caagtttgtt cataaaggtg
    24481 aggatcggcg tgtcgcgcag acgggtaact tccatcagct tacgggtacg atcttcaaca
    24541 ccttttgcgg cgtcgataac catcaggcag cagtccaccg ccgtcagggt acgataggta
    24601 tcttccgaga agtcttcatg ccccggggtg tcgagcaggt taaccaggca atcgtgatac
    24661 ggaaactgca tcacagacgt agtaatggag atcccacgct gcttttccat ctccatccag
    24721 tccgacttag cgtgctggtt ggaaccacgg ccttttactg taccggcggt ctgaatggcc
    24781 tgtccgaaca gcagcacctt ctcggtgatg gtagtcttac cggcgtccgg gtgagaaata
    24841 atggcaaaag tgcggcgctt cgccacctct tgcaaataag gagacaacgt cataattctt
    24901 tcttcttgag taagcggcat cgcgccgcgc ttgttgaaaa cgaaaaattg cggctatttt
    24961 acccatcaac gggggggagg caatcagtgt ttacacagga gctgctccag ttcatgcaac
    25021 gaagaaacgg tccaggtggg cgcgatgcct tctggttgct cgcgatggtg tgcattcagc
    25081 cagcaggtcg caagcccggc gttgatgcca ccgagaatat cggactcggc agtgtcgcca
    25141 accatcagca cgcgtgaacg gtcaggattg cccgcctgtt ccagcgcata atcgaatatt
    25201 ttcttattcg gtttagcaac gccaacttct tcggaaatca ccagcaaatc gaagtaatca
    25261 cgcaggcccg tccgttccag acgcacttgc tgcaaggcgc taaaaccgtt ggtgatgatg
    25321 ccgattttag cgttgccacg aatggcgtta agcagagaaa ccgcgcccgg caacggcgta
    25381 cagatttccg ccatcgcatt aataaaggca tcgttaagca agcctgcttc aactttcagc
    25441 cgttcggccc agctctcaaa ccgcccgtgc tgaagctgta atgaagtgat cgcgccgttt
    25501 tgataatcca cccacagtgg cttgttaacg gcctgatagt cctgaaaatc ttcagcggta
    25561 aaggtgacgc tgtaatcaag aaacatccgc tgcaggccgg tgaatgagtc aaaggtaaac
    25621 agcgtttcat cggcatcaaa gaaaatccag tcccacttca ttattccacc ttgtcttaca
    25681 tactgattgg caacgccatg atgatggcgt cttcgcgacc gtccgtggtg gggtagtaat
    25741 tgcggcgaat cgtcgcctcg ttaaagccta aactttcgta cagggcaatg gcggcagcgt
    25801 ttgaagcacg gacttccagc catagtgtcg ccacgccgcg tttttccagt tcgtcgatca
    25861 gatgttccag cagcaccctt cccaatccct gacgctgata gtcaggatcg accgcaatat
    25921 tgaacaatgt agcttcatcc agcaccactt gcgtaatcgc aaacgccgcc attttgccgt
    25981 tttgcgttaa ctgaaagttg agataacgct cgccctggtt gctggcaaag gttttttcac
    26041 tccacggaaa ggcgtgggcg cgttgttcaa tgtggtaagc cgctggtaaa tcagtcgttt
    26101 cgagggaaga aatcgtgttc atatgtgcaa atctgttgcc ataacgcggc gcgtgccgtt
    26161 gggtttgccc gtaattcggt gagcgccggt gatgccacct gagcgccttc cagtgatagc
    26221 ggttcgtcag tacccaaccg ccagctgttg cagcgactgc cttgcggcag catcgcgatt
    26281 ttttctggcg tcagttgcag cacttgatcg gggctgacgg ttaatgcgcg cagaacatcg
    26341 ctcactaaag gatcggtcag ggcgggaaga tcgtttgcca ccatcaccag acggacgtgt
    26401 gccgggatcg caatggcaat ctccccctgc aacgcgccag ggcgacgcag cgaccactgg
    26461 gtaatgccca gttgctgtaa ctgccagtct cgtcgggatg tcatagcgaa tcgctcctgt
    26521 tgtcaggggc gcaaatatag caaattcgtc gataccgcgc caacatatgg ctataatcgc
    26581 cgccagtatc aattgaggag cattccatgt ctgcatttac cccggcaagt gaagtcttgc
    26641 tgcgtcacag tgatgatttc gaacaaagcc gtattctgtt tgccggagac ttacaggatg
    26701 acctgcccgc gcgtttagat accgcggcca gccgtgctca tacccagcaa ttccaccact
    26761 ggcaggtatt aagccgccag atgggggata acgcccgttt cagtctggtc gccacggtgg
    26821 atgacgtcgc agattgcgat acgctgattt actactggcc gaagaacaaa ccggaagccc
    26881 agttccagtt gatgaattta ctttctctgc tgccagtggg gacagatatt tttgtcgttg
    26941 gcgagaaccg cagcggcgtg cgcagcgccg agcagatgct ggcagattat gcgccgttga
    27001 ataaagtcga cagcgctcgt cgctgtggcc tctattttgg tcgtctggaa aaacagccgg
    27061 tatttgatgc cgataaattc tggggcgaat acagcgtcga tggcctgacg gtcaaaacgc
    27121 tgcctggcgt gtttagccgc gacggtctgg atgtcggtag ccagttgctg ctctcgacgt
    27181 taaccccgca cacgaaaggt aaagtgctgg atgtcggctg tggcgcgggt gtgctttcag
    27241 ttgcctttgc gcgccattcg ccgaaaattc gtctcacctt gtgcgatgtc tctgcgccag
    27301 cggtagaagc cagccgcgca acacttgcgg ccaacggtgt tgaaggtgaa gtctttgcca
    27361 gcaacgtctt ttccgaggtg aaaggtcgtt ttgatatgat catctccaac ccgccgttcc
    27421 acgatgggat gcaaaccagc ctggatgcgg cgcaaacgct gattcgcggc gcggtgcgtc
    27481 atcttaatag cggcggcgag ctgcgaattg tagcgaacgc cttcctgcct tacccggacg
    27541 tgctggatga gacatttggc ttccatgaag tgattgcgca aaccgggcgt ttcaaggtgt
    27601 atcgcgccat tatgacccgc caggcgaaga aaggttaatt atctcgccga ataccgtgtc
    27661 ggatgcggcg tgaacgcctt atccgaccta caaaacctgc acgttagccc ttcgtaggcc
    27721 agataagacg cgccagcgtc gcatctggca tctgcccccg catgcctacc aaacctgcac
    27781 gctagtttcc tgatggacat ttttccagca attacacctc cggcgataat taactattga
    27841 cgaaaagctg aaaaccacta gaatgcgcct ccgtggtagc aattcttttt aagaattgat
    27901 ggtatgcgaa ggtggcggaa ttggtagacg cgctagcttc aggtgttagt gtccttacgg
    27961 acgtgggggt tcaagtcccc cccctcgcac caattatctt tacttccttt cttgtttctt
    28021 ccttgatttt tcatccctga ttcaaattca ttatcatcag catgatgcca gcaataagcg
    28081 ccaggcacga tggtagcaaa acgtaatgcc gtaactgttt gtgatacagc atcaccggcg
    28141 tcaatactaa tcccatcaga atgacaatcc gccactgatc cggcgataaa tccgcataca
    28201 tcagccctgc aatcagcaat cctggcagca acactcccca gccactgccc agcatacgtt
    28261 gcaacatggt ttcatctctt tcattgataa tgataaccaa tatcatatga taatttttat
    28321 catttgcaag ccagagaaat cccttgctat cgggtaaacc tatcgctagg attagcaatc
    28381 attatcattt agattactat cccgattatg gcctatcgtt ccgcaccgct ctatgaagat
    28441 atcatctggc gaacgcatct ccagccgcag gatgctgggc ttgcacaagc cgtacgtgcg
    28501 acgatcgcca aacatcgtga acatttgctc gagtttatcc gcctggatga acccgctccg
    28561 cttaacgcca tgacgctggc gcaatggtca tcaccgaatg cgctaagttc tctactcgcg
    28621 gtctattccg atcatatcta tcgcaaccaa ccaacgatga tccgcgagaa caaaccgctg
    28681 atctcactat gggcacaatg gtatatcggc ctgatggtgc caccattaat gctggcgcta
    28741 ctgacgcagg aaaaggcatt agatgtgtcg ccggaacatt tccatgctga gtttcacgaa
    28801 accggccgtg ccgcctgttt ctgggtcgat gtgtgtgaag ataaaaacgc aacaccacat
    28861 tcgccgcagc agcgaatgga aaggttaatc agccaggcgc tggttccggt tgtgcaggca
    28921 ctagaagcga ccggagagat caacggcaaa cttatctgga gtaataccgg ttatttgatc
    28981 aactggtatc ttactgagat gaagcaactg ctcggcgagg cgacggttga atcgctgcgc
    29041 catgccctct tttttgagaa aacgctcacg aacggtgaag ataatccact ctggcgtacc
    29101 gtggtactgc gcgatggcct gctggtgcgc cgcacttgct gccagcgtta tcgcttaccg
    29161 gatgtgcagc aatgtggcga ttgtacgctg aaatgaaagc actgccgggg aagtaaaccc
    29221 ggcatcatgc ggattaatag ggatgcaaca cattacttgt ttcgcaatgc cgcatacata
    29281 acagaatatc tgcggcctcc aacaaccctg catcagaact gacgcccagt ttcgacatca
    29341 cattaaattt atgtgcacgg atcgttttga tattacgttt aagctgctcg gcaatttgtg
    29401 tcattgagta gccacgcgac ataaagcgca atatttctct ctccgtcggg cttagcgtcc
    29461 ggctttggtt aatgtaccac tgattgttca gtcggtcggt cgcctgacgt acaccattta
    29521 atgacaaaaa gagttcctga tgaaaaatct ccagcgttga cgctttactt aatacaccgt
    29581 ccagcggtga tggcgacaat gaaccaatca gccgagcttc aatatcatca tccgcaataa
    29641 ctaaacgccg ggtacgcgga aacttaatcg ccagttcagt caggcaagat aatccctctc
    29701 tgcgctcact tctcatggca gaaaaagaaa aaatgaccgc cgtaaacgag atccgcgaca
    29761 tggcatcctg aaatgactcc tgactggtat aggtatggag cttataaggg ctacccgcaa
    29821 actttctgaa taaactctca ataccgatac tactcatgac gcatttttct atgagtgcga
    29881 catttctctt cttaattcgg ctgtgttcca ttctgcggca tctccataaa cagaaggcaa
    29941 gttaagttct cttgcaccct gcgcgctatt tatccatgca tacatttcag cgttgctgtg
    30001 aattgccagt cgacgcatcg cactgttttt ttgggcgctg atagttttat tacttttctt
    30061 aagcaatgaa gctatctggt tgatgcccca tcctttacct aatagccgca gtaccttgcg
    30121 ctctgaaaga gtgagaatga cggagcgata gctaaaatca tgagtttcag tcattgccgg
    30181 agaggtcagc atggcgctga tacgctctgc gtgcgtattg ccggaacgta cggtcttgac
    30241 cagattctca atgggttcaa catcagacaa taacgtcgcc gtagggcaca tgagcagttc
    30301 tactgcctgg gaataccagg agcgtgacac catgaaaacc cagtgaattt cccgatattg
    30361 tgagattaaa gaataataat gttcacaaac agaacgtgga tcttcacttt caccggctaa
    30421 atcagcaatg actaatccgg aacgacgtaa ttgtaataag gtaaggtcct ccgcagaggc
    30481 gctggatatt atttcatatt cagggaagtg agtcctcatg acctctttta gccctgcttg
    30541 cataacaggt attttactga taacaattcc atttttgcag catcctggca acatatttcc
    30601 tccacatcca ctgtctaaaa attatgatgg tttattcagg atattcattc cttaaatgtt
    30661 tccagcaaat taatagatta agcgaataaa ttatccttag cattcacttt catatcagca
    30721 tactcctgct gcacaacaac tccactgcat gtgtcagaag gttagcatca aatgataacc
    30781 tggtgaaata gcctggagac atttaaaata tctacattaa gttgttagga atacttaatg
    30841 aaaaacagaa atcacattca tttaatttat aattaaatga tatcccttcc tgcagaatga
    30901 aaaatcacac aaccaatatt tattcaatga aatctgatgg ttttaacttg ttaacattaa
    30961 aaaacgtgcc cggttatcta ttatcctgat tcgtaaaggc caaacaataa attcattatg
    31021 atgataatat tcatgtgata gtttgtttgc ggcgagagat aattcgcttt ttatcaccga
    31081 gcttctcccg ataaccagga ttaatcagcg caattttgat cttaacctac cgcaaaacaa
    31141 ccgtgcttca tgatacaaat ggattctcat tatctgaaca atacgcagca cgtctatgac
    31201 aaagggcgag ttatgcaaac tgagcaacag cgagccgtaa cacggctttg tatccagtgt
    31261 ggattatttc ttctgcaaca tggtgcggaa agcgcgttgg ttgatgagct ttcctcacga
    31321 ctgggtcggg cgctgggaat ggacagcgtt gaaagttcta tctcttcgaa cgccatagtg
    31381 ctgacaacca ttaaagatgg gcaatgcctg acatcgacac gtaaaaatca cgatcgcggc
    31441 attaatatgc atgtggtgac tgaagtccag cacattgtga ttctggcgga gcaccatctg
    31501 ctggattaca aaggcgtaga gaaacgattt agccaaattc agccattacg ttacccaaga
    31561 tggctggtag ccttaatggt tggcctttcc tgcgcctgtt tctgtaaact caataaaggt
    31621 ggctgggatg gtgccgtcat caccttcttt gccagtacgg ccgcgatgta tatccgccag
    31681 ctactggcac aacgtcatct tcatccacag atcaactttt gcctcaccgc tttcgccgcc
    31741 accactattt ccggtttgct tttgcaactt cccaccttca gcaatacacc caccattgcg
    31801 atggccgcca gcgttctgct gctggtgccg ggatttccgt tgataaatgc cgtcgccgat
    31861 atgtttaaag gccacatcaa taccggactg gcacgctggg cgatcgccag tctgctgaca
    31921 ctggctacct gcgtcggcgt ggtgatggca ctgacgattt gggggctacg cggatgggtg
    31981 tgatcgagtt tctgtttgca ttggcgcagg atatgatcct cgccgccatt ccagcggtcg
    32041 gctttgcgat ggtgttcaac gttcccgttc gggcattacg ctggtgtgcg ctgcttggcg
    32101 cgattggtca tggttcacga atgatcttaa tgaccagcgg gctgaatatt gagtggtcaa
    32161 cctttatggc ttctatgctg gtcggcacca ttggtattca atggtcgcgc tggtatctgg
    32221 cgcatccgaa agtgtttacc gtggcggccg ttatccctat gttcccgggc atatcggctt
    32281 ataccgcaat gatttcggcg gtaaaaatca gccagttagg ttacagcgaa ccgttgatga
    32341 ttaccctgtt aaccaacttt cttacagctt catcgattgt tggtgcgtta tccatcggtc
    32401 tttccattcc tggattatgg ttgtaccgca agcgccctcg cgtataaaat tgcctcgctt
    32461 aagcacacgg atgagagaca gcctcctctc ctccgtgtgt tactataaaa gttatctccc
    32521 ttctcgttca tcgttccata tttgagaaac agtatgtctt ccagagtttt gaccccggac
    32581 gtcgttggta ttgacgccct ggtacacgat caccaaaccg ttctggcaaa agctgaaggc
    32641 ggtgtggttg ccgtatttgc taacaatgcc ccggcgtttt atgccgtcac gcctgcacgc
    32701 ctggctgaac tgctggcgct ggaagaaaag ctggcgcgtc cgggaagcga tgtcgctctg
    32761 gacgatcaac tctatcagga accgcaagcc gctcccgttg ctgtccccat ggggaaattc
    32821 gccatgtatc cggactggca acccgatgcc gactttatcc gcctggcggc gctatggggc
    32881 gtggcgctaa gagagccggt gaccaccgaa gaactggcct cattcattgc ctactggcag
    32941 gcggaaggta aagtctttca ccatgtgcag tggcaacaaa aactggcgcg cagcctgcaa
    33001 atcggtcgtg ccagcaacgg cggactgccg aaacgagatg tgaatacggt cagcgaacct
    33061 gacagccaaa ttccaccagg attcagaggg taacgatgaa aaacgttggc gacctgatgc
    33121 aacgcctgca aaaaatgatg cctgcccata tcaaacctgc attcaaaacg ggtgaagaac
    33181 tactggcctg gcagaaagaa caaggagcga tccgctccgc cgctctcgaa cgtgaaaatc
    33241 gggcgatgaa aatgcagcgc acctttaacc gctccggtat tcgtccactg catcagaact
    33301 gctcctttga gaactatcgc gttgagtgtg aagggcagat gaatgcgtta agcaaagcgc
    33361 gccagtatgt cgaagagttt gacggcaaca tcgccagctt catcttttct ggtaagccag
    33421 gaaccggcaa aaaccatctg gcggcggcaa tctgcaacga gctgctgcta cgcggtaaat
    33481 ccgtattgat catcaccgtg gccgatatta tgtcggcgat gaaagatacc ttcaggaata
    33541 gcggtaccag cgaagaacaa ctgcttaacg atctgagcaa cgttgatctg ctggtgatcg
    33601 atgagatcgg cgtgcagacc gaatcgaaat acgaaaaagt gatcatcaac cagatcgtcg
    33661 atcgccgctc ttcttccaaa cgcccaaccg ggatgctgac caacagtaat atggaagaga
    33721 tgaccaagtt gctgggcgaa cgcgtgatgg accgtatgcg cctgggtaac agtttgtggg
    33781 tgatcttcaa ctgggatagc taccgtagcc gtgtaacagg taaagagtat taatccccgt
    33841 ttctggcggt atactgcgac acaattccac cttgagtaat gatgatgaaa actgttaaac
    33901 atcttctgtg ctgtgccatt gccgccagcg cattaatttc caccggggtg catgctgcgt
    33961 cctggaaaga tgcgctctcc agcgccgcca gcgaacttgg caaccaaaac agtacgacac
    34021 aggaaggcgg ttggtcgctc gcgtcattaa ctaacttgct tagcagcgga aaccaggcct
    34081 taagcgcaga taacatgaac aatgccgcag gcattctgca atactgcgcg aagcaaaagc
    34141 tggcttcggt aaccgatgcc gaaaacatca agaaccagat gctggaaaag ctgggcctga
    34201 acagtgaaga gcaaaaagaa gacaccaact atctggacgg cattcagggt ttgctgaaaa
    34261 ccaaagatgg tcagcaactc aatctggata acatcggaac gactccgctg gcagaaaagg
    34321 tgaaaaccaa agcctgcgat ctggtgttaa agcaggggct gaacttcatt tcctgaaccg
    34381 cgaaacgccg cgttttagct gttacccggc tgacgcggct ctctcctgcc cttttccctg
    34441 ctcctggacg gttttccccc tgttacacgg gaagcgaccg cgatcaaaaa agtctgttta
    34501 taaactaatt cctaacaaca tcgcattttt ttgacactag aattgcagca atatggcgac
    34561 gccattacat tgtgcttctc aaaaagctta aacgttggct aaacggcccg gtttagtgag
    34621 gatcgcccgt tgtcagaact actctctttc gccctttttc tcgcctctgt gctgatttac
    34681 gcatggaaag cgggacgtaa cacctggtgg tttgcagcca cattaacggt gctggggcta
    34741 tttgtcgttt taaatatcac cctgtttgcc agcgactatt ttactggcga tggtattaac
    34801 gacgcggttc tctatacctt aaccaacagc ctgaccggtg ctggcgtcag caaatacatc
    34861 ctgccgggta tcggcattgt gctggggctg acagcggtgt tcggtgcgct gggctggatc
    34921 ctgcgccgtc gtcgccatca tccgcaccat tttggttaca gcctgctggc gctcttactg
    34981 gcgctgggtt cggtggacgc cagcccagca tttcgtcaga taacggaact ggtgaaatcc
    35041 cagtcacgcg atggcgaccc ggactttgcg gcttattata aagagccgtc gaaaactatc
    35101 cctgacccga aactcaacct ggtttatatc tacggcgaaa gtctcgagcg gacctatttt
    35161 gataacgaag ctttcccgga tctcacgcct gaactgggcg cgttgaaaaa tgaaggcctg
    35221 gatttcagcc acacgcagca gctgccagga acggattaca cgattgcggg catggtggct
    35281 tctcagtgcg gcataccgct gtttgccccc tttgaaggca acgcctccgc ctctgtctcc
    35341 agcttcttcc cgcagaacat ctgtctgggc gatatcctga aaaactcggg ttatcagaac
    35401 tatttcgtgc agggcgcgaa tctgcgtttt gccggtaaag atgtgttcct gaagtcgcat
    35461 ggcttcgacc acttatacgg ctcagaagag ctgaaaagcg tggtggccga cccgcactat
    35521 cgcaacgact ggggattcta cgacgatacc gttctcgatg aagcgtggaa aaagtttgaa
    35581 gagctttccc gctcaggtca gcgattctca ctgtttaccc tgacagtcga tacccatcac
    35641 ccggatggtt ttatctcgcg tacctgtaac cgcaaaaaat atgattttga cggtaagccg
    35701 aaccagtcat tcagcgcggt aagttgcagc caggagaata tcgcggcgtt tatcaacaaa
    35761 atcaaagcgt caccgtggtt taaagatacc gtcatcgtcc tctcttctga ccatttagcg
    35821 atgaacaaca cggcgtggaa ataccttaat aagcaggatc gcaataacct gttttttgtc
    35881 attcgtggcg acaagccgca gcaagagacg ctggcagtga agcgtaacac gatggataac
    35941 ggcgcgacgg tgctggacat tctcggtggc gataactatc tcggacttgg tcgtagcagt
    36001 ttatccgggc agtcaatgtc ggaaatcttc ctcaatatca aagagaaaac attggcgtgg
    36061 aagccggata tcatccgcct gtggaaattc cctaaagaga tgaaagagtt caccatcgac
    36121 cagcagaaaa acatgattgc cttctcgggt agccatttcc gtttgccgct gctgttgcgg
    36181 gtttcagaca aacgcgtgga accgctgccg gaaagcgaat actcagcacc gctgcgtttc
    36241 cagctggccg atttcgctcc acgcgacaat ttcgtctggg ttgaccgttg ctataagatg
    36301 gcacaactct gggctccgga actggcactc tccaccgact ggtgtgtctc gcaagggcag
    36361 cttggcggtc agcaaattgt tcagcatgtt gacaaaacaa catggcaggg caaaacggca
    36421 tttaaagata cggtcatcga catggcgcgt tataaaggca atgtcgatac gctgaaaatt
    36481 gttgataacg atattcgcta caaagccgac agtttcatct tcaacgtcgc cggtgcgcca
    36541 gaagaggtga aacagtttag tgggatttcc cgtccagagt cgtggggccg ctggtccaac
    36601 gcgcagctgg gcgatgaagt aaaaatcgag tacaagcatc cgctgccgaa gaaatttgac
    36661 ctggtgatta ccgccaaagc atacggcaat aacgccagcc gtcctattcc ggtacgcgta
    36721 ggcaatgaag aacaaactct tgtgctgggc aatgaagtga ccaccaccac actgcatttc
    36781 gataacccaa ccgatgccga cacactggta attgtgccgc cggaacctgt ctcaaccaac
    36841 gaagggaata tcctcggaca ctcgccgcgt aagctcggga tcggcatggt ggaaattaaa
    36901 gttgtggaac gtgaagggta atttctgact gatgtgtagg tcgcataagg tgcgacctac
    36961 acatcttctc cggcctacaa aacatcattg agaaacagaa aaaaaacagc gcccaacact
    37021 tccccggacg ctgcatggca actttaataa tctcgcctta tcagaaagta attacaccct
    37081 taatcaactc acgattgtta atcacatcgc gctcgtaggt ttctgccagc gtggcgaact
    37141 gatagcgatg ggttaacatc atgtcggcag tgatttttcc ttccgccatc agtcgaccga
    37201 ctttagcaaa atcttccggc gtggcgttgc ggctgcccat catcgtcgtt tcttttttat
    37261 ggaattccgg atcggagaac tgcaactcac ctttaaacag gccgacaaat accaccgtgc
    37321 cgccgtgacg aatcaaattc acggtgttat tcatcgcatg ttgattacct gtcgcgtcga
    37381 tcactttctg cgccagcgaa ccaccaaact gcgcccgtag ctgcgcgtca aaatcttcgg
    37441 ctgacgggtc cagtaaaggt aattccagac gcgttgccac atgttcacgg cgcgccggac
    37501 tggtatccgc caccaccacc tgtgcgccat cggctttagc gattgccgcc gcgcccaaac
    37561 cgattggccc cgccccgacc accagcacct gctcgccggg agcaatggct gcgcgacgca
    37621 ccgcatgagc gctaatagcg aaaggttcaa tcaatgcggc cgcctgcggg tcaataccgt
    37681 ctgcgggcaa aatgttcgcc accggcacgc tcaaatactc actaaaaccg ccatcctgat
    37741 gcacgccaat gactgaaatt ttttcacagc aattggtacg cccgctttta cacgccgggc
    37801 attgctgaca ggcaacataa gggatcacag caacttgctg accattttta agatcagcaa
    37861 tatttttacc cagcccaaca atctccccac atatttcatg gcctaaaaca cgtggataac
    37921 taaaaaatgg ttgatttcca ccccaggcat gaatatcggt accgcaaatc ccgacagact
    37981 taatttttat taatgcttca ttgtcacccg gaataggtat ctcgcgttgt ttccagacta
    38041 attctttcgg ctgctggcaa attaaaacat tcatcgtaga catgattcgg ctctccattt
    38101 tttgttgcct tagatatcaa tgaaaatgaa aaatggcagc ggaacggaaa atctgttttg
    38161 tgaaaacaca cgcataaaaa tgttttaaat cgggttttaa tggactcaca aggaggaaaa
    38221 tatgagtcgt tcacaaaatt tacgccacaa tgtgattaac caggtcattg atgatatggc
    38281 gcggggtcat atcccttccc cacttccatc gcaaagtgcg ctggcggaaa tgtacaacat
    38341 cagccgcaca acagtgcgtc atattctcag ccacttacgc gaatgcggcg tcttaacgca
    38401 ggttggaaac gactatgtta ttgcgcgtaa acctgaccat gatgacggtt tcgcctgtac
    38461 taccgcttca atgagtgaac aaaacaaagt gtttgagcag gcttttttca cgatgataaa
    38521 ccagcgtcag ttacgccctg gggaaacttt ttctgaactg caactggctc gggccgcggg
    38581 tgtcagcccg gtggttgtaa gagaatatct tttaaaattc ggccgttata atcttattca
    38641 aagcgaaaaa cgcggccagt ggagcatgaa gcaattcgat caatcctacg ccgagcagct
    38701 gtttgagcta cgcgaaatgc tcgaaacaca ttcacttcag cactttctca acctgcctga
    38761 tcatgatccc cgctggctgc aggcgaaaac catgctcgaa cgtcatcggc tactgcgtga
    38821 caacatcggc aatagctttc gcatgttctc gcaacttgac agagattttc actccttact
    38881 gctttcagct gccgacaata tcttttttga tcaatcgctt gagatcatct cagtcatctt
    38941 tcattttcac tatcaatggg acgaaagcga tcttaaacag cgcaatatca ttgccgtcga
    39001 tgagcatatg accattctca gcgctctgat ttgccgcagt gaccttgatg ccacccttgc
    39061 gctccgtaac catttgaatt cagctaaaca atccatgatt cgatccatta atgagaacac
    39121 gcgttatgct cattaagtac ggattaaaaa cagcaaacta ttagcgggtg cacggtttta
    39181 tcaaaagata aataccggga aattcccgct tacctatgct cacaatcagt cgactaaaaa
    39241 tttttttgtg agcggtagta aagtcctaaa actttaacct gccgttaatg tcaaccttgc
    39301 gtaattcaca attacgtaaa caattaaaat tataaataca ggagtccggc gtggaaaaag
    39361 aaaatatcac cctcgatccg cgttcttcat ttactccatc ttcgtcggca gatattcccg
    39421 tgccaccaga tggattagtt caacgcagta cccgaattaa acgcattcaa accaccgcca
    39481 tgttgttatt attttttgcg gcggtaatca attatctcga ccgcagttcg ctgtcggtag
    39541 caaatttaac gattcgtgaa gaattgggat taagtgccac cgaaatcggc gctttgctct
    39601 ccgtgttttc actcgcttac gggattgcgc aacttccttg cggcccacta ttggatcgta
    39661 aaggcccacg cctgatgctg ggactgggga tgttcttctg gtcactgttc caggcaatgt
    39721 ctggcatggt gcacaacttt acgcagttcg tgttggtgcg tatcggtatg gggattggtg
    39781 aagcgccgat gaacccatgc ggtgtaaaag tcattaacga ctggttcaac atcaaagagc
    39841 gcggacgccc gatgggcttc ttcaacgcag cttctaccat tggcgttgcc gtaagcccac
    39901 cgattctggc ggcgatgatg ctggtgatgg gctggcgcgg gatgtttatt accattggtg
    39961 tactggggat ttttctcgcc atcggctggt atatgctcta tcgcaaccgc gagcacgtag
    40021 aactgactgc cgttgaacaa gcttatctca atgcaggtag cgtcaatgcc cgccgagatc
    40081 cgctcagttt tgccgaatgg cgcagcctgt tccgtaaccg tacaatgtgg ggaatgatgc
    40141 tcggattcag tggcatcaac tacactgcgt ggctgtatct ggcctggctt cctggttacc
    40201 tgcaaacagc ctataacctg gatttaaaaa gcacagggtt gatggcggct atccctttcc
    40261 tgtttggggc tgccgggatg ctggtcaacg gttacgttac tgactggctg gtcaaagggg
    40321 gaatggctcc gattaaaagc cgtaagatct gcattattgc cgggatgttc tgttctgccg
    40381 cctttacgct gatagtacca caagcgacaa catccatgac ggcggttctg ctgattggca
    40441 tggcactgtt ctgtattcac tttgccggaa catcctgctg gggcttgatc cacgtcgcag
    40501 ttgcttctcg catgactgcg tcggtgggca gtatccagaa ctttgccagc ttcatctgcg
    40561 cctcttttgc gccgatcatt actggtttta ttgttgatac cacccactca ttccgtctgg
    40621 cactaatcat ctgcggttgc gtcaccgcag cgggggcact ggcgtacatc ttcctggttc
    40681 gtcagccgat caacgaccca cgtaaagatt aatctcctta tgcccgataa cattttgctt
    40741 atcgggcatt ttcatggcga ttaaaatgtt tcccagttct cctcgctatc tgccacggcc
    40801 attttacgcg gcgcagctgg cgtcacggtt tttaccacag ccgatgtttc acgctgctgt
    40861 tgctgctgtt gctgaatccg gaacactgcc acagcttcgg tcaggcgact ggcctgctct
    40921 tccagcgcgg cggcggcagc ggcagattct tccaccagcg cggcgttctg ttgagttacc
    40981 cggtccatct cagcaaccgc taagccaacc tgatcgatac cacggctctg ctcatcagaa
    41041 gcagaagcaa tttcgcccat aatgtccgtc acgcgggtca cggcgctgac aatctccgcc
    41101 attgtttccc cggcgctttc gaccagcgta gagccaacat ccactttccc caccgagtct
    41161 tcaatcaggc ttttaatttc acgagccgcc tgagcgctac gctgggccag attacgcact
    41221 tctcccgcaa ccaccgcaaa accgcgccct tgctcacccg cacgcgctgc ttcaaccgcc
    41281 gcgttcaaag ccagaatatt ggtctggaag gcaatgccgt caattacgct gataatatcg
    41341 gcgattttct gcgaactggt ggagatatcg cgcatagtct gcaccacgtt atctaccact
    41401 ttgccgcccc gttgcgccgt ttcagaagca cttaatgcca gatggctggc ctggcgcgca
    41461 ttctcggcgt tctgtttcac cgttgcggtc agttgctcca tgctggctgc cgtctcttcc
    41521 agcgaagcgg cctgttgctc ggtgcgcgaa gagagatcgt tattgccggt agcgatttcg
    41581 ctggcaccgc tatagatggc attggccccg ttgcgcacat caccgacggt acgcatcagc
    41641 tctccctgca tatggcgcaa actctctgcc agttgcccca tctcattaga gccatccacc
    41701 tcaatcggtt tcaccagatc gccgcctgca atatgacgaa tgctgtcaat caggcgattc
    41761 attggcgcta ccagcgaggc tttaataccg aaccagacgg cgaagatgac cgccagtacg
    41821 acgatcatca cgcccaccag aatccacatc gcctggctgt aggaggcatt gttatcgctg
    41881 acggcgatat catagagccg atcgttttgc tccatgtaag ccacatactg cttctcgaaa
    41941 ccgtcctgat atccctgagt cggctgatca aagaactcgt tgattttgcc tgcacctaac
    42001 agttggatca gctccgccag cgcattgtga taaatatcgt aattacgttt gatctctgcc
    42061 gctgcggcgg tgctctgacg cgggtcacgc ggcaacgctt cgtaatccgc ccagtttttt
    42121 tccgcctgtt tcagcgaaat actggcactc tgcatcagct cagcaacggt tgaaccgcta
    42181 ccaatattat tctgatccat catgtagcgg atacccgcgc ggttgagggt gttacgcgtc
    42241 tgcaacaacg cgacccagct gccattcagc gtggattgct gctggcgaat ggtttgtaaa
    42301 acagtgaaat tttctttgtc attctttaag gcattaaaga acagaccgcc tgatgtcagt
    42361 tgtaaaaggc caaaaacggc caaaaccagc agtaagctgg tcacgatctt gatacgtttt
    42421 aacatggttt ctctttcctg tggaccgatg caagattttc ggcctggaaa gcaaaaactt
    42481 tatgaaaagg tgtaacccgc catccatgga aaaaccaggc gctggttatc agatactaaa
    42541 aagttattca ttatcgcccg ggatgtcttc ttgtcgggaa ttgcccagag caataaattc
    42601 ctctaacaaa tgggttaact gttgcatttt ctcggcagtg aactgagctt caatctgccg
    42661 ataggcttct tcaatctgtg tctgagcgcg gttatacagc gcctgcccct ctttggtcag
    42721 cgagatatag agcttccgct gatcattgat cggctttaat cgcaacacta aaccgtcgcg
    42781 ttccatccgc gtaaggatcc cggtcaggct tgggcgcaaa atgcaggcgc gatacgccag
    42841 atcgtgaaaa tccattgatg ggctctccgc cagaatacgc acgatgcgcc actgttgctc
    42901 agtcaaatta tgccgtttaa cgattgggcg aaaataactc atcgccgctt ctcgcgcctg
    42961 gagcaacgca atggttagag agtcgtgcat tatctttccc ctgaaaaatt caaaatcatt
    43021 aatatagaaa cagttaatca tcacgttacc g
//
LOCUS       DAZUDJ010000039        43003 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.039, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000039 DAZUDJ010000000
VERSION     DAZUDJ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43003
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.039"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            48..341
                     /gene="eutM"
                     /locus_tag="ACHY1N_002814"
     CDS             48..341
                     /gene="eutM"
                     /locus_tag="ACHY1N_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HFS4045103.1"
                     /translation="MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAM
                     VRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHGDLEEVFPIGLKGDSSNL"
     gene            448..735
                     /gene="eutN"
                     /locus_tag="ACHY1N_002815"
     CDS             448..735
                     /gene="eutN"
                     /locus_tag="ACHY1N_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HFS4045104.1"
                     /translation="MKLAVVTGQIVCTVRHHGLAHDKLLMVEMIDPQGNPDGQCAVAI
                     DNIGAGTGEWVLLVSGSSARQAHKSETSPVDLCVIGIVDEVVSGGQVIFHK"
     gene            747..2150
                     /locus_tag="ACHY1N_002816"
     CDS             747..2150
                     /locus_tag="ACHY1N_002816"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004029 - aldehyde dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HFS4045105.1"
                     /translation="MNQQDIEQVVKAVLLKMQSSDTPSAAVHEMGVFASLDDAVAAAK
                     VAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAP
                     HPAAKKVSQRAITLLNQAIVAAGGPENLLVTVANPDIETAQRLFKFPGIGLLVVTGGE
                     AVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAEQAQQLQPVLLKNIDERGKGTVSRDWVGRDAAKIA
                     AAIGLNVPQETRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHH
                     TAAMHSRNIENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSAR
                     TFVRLRRCVLVDAFRIV"
     gene            2161..2997
                     /gene="eutJ"
                     /locus_tag="ACHY1N_002817"
     CDS             2161..2997
                     /gene="eutJ"
                     /locus_tag="ACHY1N_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HFS4045106.1"
                     /translation="MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSM
                     VVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGRRFSHAATSFPP
                     GTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVT
                     YSADEATGGHHISLTLAGNRRISLEEAEQYKRGHGDEIWPAVKPVYEKMADIVARHIE
                     GQGITDLWLAGGSCMQPGVAELFRKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLY
                     AK"
     gene            2987..4174
                     /gene="eutG"
                     /locus_tag="ACHY1N_002818"
     CDS             2987..4174
                     /gene="eutG"
                     /locus_tag="ACHY1N_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HFS4045107.1"
                     /translation="MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGAVSSCGQQA
                     QTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAMTLWLCPVGEPCITDVCAAVAQL
                     RESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
                     GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRERFSQIGRALRTKKSDDRD
                     AINAVSELIAEVGIGKRLGDVGATSAHYGAWAQAAQEDICLRSNPRTASLEQIVGLYA
                     AAQ"
     gene            4291..5517
                     /gene="eutH"
                     /locus_tag="ACHY1N_002819"
     CDS             4291..5517
                     /gene="eutH"
                     /locus_tag="ACHY1N_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0034228 - ethanolamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034229 - ethanolamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HFS4045108.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGS
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPE
                     KMINGFQIFAKFLVALITLGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLV
                     PKEDATATKTEAEAQS"
     gene            5514..6917
                     /gene="eutA"
                     /locus_tag="ACHY1N_002820"
     CDS             5514..6917
                     /gene="eutA"
                     /locus_tag="ACHY1N_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HFS4045109.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYEFIKR
                     EISWQSPVFFTPVDKQGGLKEAELKSLILEQYQAAGIAPESVDSGAIIITGESAKTRN
                     ARPAVMALSQSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANY
                     ALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGAGTDARSLTGAQL
                     VQVTRRMAALIVEVIDGTLSPLAQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADP
                     FCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEGVQL
                     PLRNLPVAIPIDETDLVSAWQQALLQLDLDPKTDAYVLALPASLPVRYAAVLTVINAL
                     VDFVARFPNPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            6929..8290
                     /gene="eutB"
                     /locus_tag="ACHY1N_002821"
     CDS             6929..8290
                     /gene="eutB"
                     /locus_tag="ACHY1N_002821"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit alpha"
                     /protein_id="HFS4045110.1"
                     /translation="MKLKTTLFSNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSAR
                     LQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNI
                     PTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPS
                     LFF"
     gene            8311..9198
                     /gene="eutC"
                     /locus_tag="ACHY1N_002822"
     CDS             8311..9198
                     /gene="eutC"
                     /locus_tag="ACHY1N_002822"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit beta"
                     /protein_id="HFS4045111.1"
                     /translation="MDQKQIEEIVRSVMASMGQTAPAPSEAKCATTNCAAPVTSESCA
                     LDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRS
                     KDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPD
                     VQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILG
                     AKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVI
                     VDLAKRMLEQKASGINMTR"
     gene            9208..9867
                     /gene="eutL"
                     /locus_tag="ACHY1N_002823"
     CDS             9208..9867
                     /gene="eutL"
                     /locus_tag="ACHY1N_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031469 - bacterial microcompartment
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HFS4045112.1"
                     /translation="MPALDLIRPSVTAMRVIASVNAEFARELKLPPHIRSLGLISADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MVAHIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATY
                     GIDAALKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQR
                     A"
     gene            9880..10380
                     /gene="eutK"
                     /locus_tag="ACHY1N_002824"
     CDS             9880..10380
                     /gene="eutK"
                     /locus_tag="ACHY1N_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416933.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HFS4045113.1"
                     /translation="MINALGLLEVDGMVAAIDAADAMLKAANVRLLSHEVLDPGRLTL
                     VVEGDLAACRAALDAGCAAAMRTGRVISRKEIGRPDDDTQWLVTGFNRQPKQPVREPD
                     APVIVAESADELLALLTSVRQGMTAGEVAAHFGWPLEKARNALEQLFSAGTLRKRSSR
                     YRLKPH"
     gene            10426..11478
                     /gene="eutR"
                     /locus_tag="ACHY1N_002825"
     CDS             10426..11478
                     /gene="eutR"
                     /locus_tag="ACHY1N_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HFS4045114.1"
                     /translation="MKKTRTANLHHLYHEPLPENLKLTPKVEVDNVHQRQTTDVYEHA
                     LTITAWQQIYDQLHPGKFHGEFTEILLDDIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGEQGFIGSQCLGSAEIATRPGGTEFELSTPDDYTILGVVLSEDVITRQANFLHNPD
                     RVLHMLRSQSALEVKEQHKAALWGFVQQALATFCENPENLHQPAVRKVLGDNLLMAMG
                     AMLEDAQPMVTAESISHQSYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVKDAAMQWGFWHLGQFATDYQQLF
                     AEKPSLTLHQRMREWG"
     gene            complement(11484..12383)
                     /gene="hemF"
                     /locus_tag="ACHY1N_002826"
     CDS             complement(11484..12383)
                     /gene="hemF"
                     /locus_tag="ACHY1N_002826"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004109 - coproporphyrinogen oxidase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HFS4045115.1"
                     /translation="MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGG
                     RSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYV
                     PTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVY
                     PRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVE
                     RRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DYQPKDGSPEAALSEFIKVRDWV"
     gene            complement(12387..13256)
                     /gene="amiA"
                     /locus_tag="ACHY1N_002827"
     CDS             complement(12387..13256)
                     /gene="amiA"
                     /locus_tag="ACHY1N_002827"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HFS4045116.1"
                     /translation="MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDEPLKTSNG
                     HSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDA
                     RLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKL
                     HSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYF
                     HWFDNQKAHSKKR"
     gene            13470..13895
                     /locus_tag="ACHY1N_002828"
     CDS             13470..13895
                     /locus_tag="ACHY1N_002828"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311332.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HFS4045117.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSL
                     FLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY"
     gene            13882..14331
                     /locus_tag="ACHY1N_002829"
     CDS             13882..14331
                     /locus_tag="ACHY1N_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HFS4045118.1"
                     /translation="MKSTEFHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASR
                     EQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRATFPRTWHVLYFLLLLAQVVL
                     LCWQPWLWLNGESVSGIGLALVVADIVALIWLLTNRRLRACFNEVKE"
     gene            14392..14967
                     /locus_tag="ACHY1N_002830"
     CDS             14392..14967
                     /locus_tag="ACHY1N_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HFS4045119.1"
                     /translation="MKSLRLMLCAMPLMLTGCSTMSSVNWSAANPWNWFGSSTKVSEQ
                     GVGELTASTPLQEQAIADALDGDYRLRSGMKTANGNVVRFFEVMKGDNVAMVINGDQG
                     TISRIDVLDSDIPADTGVKIGTPFSDLYSKAFGNCQKADGDDNRAVECKAEGSQHISY
                     QFSGEWSGPEGLMPSDDTLKNWKVSKIIWRR"
     gene            15063..15962
                     /gene="yfeX"
                     /locus_tag="ACHY1N_002831"
     CDS             15063..15962
                     /gene="yfeX"
                     /locus_tag="ACHY1N_002831"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311329.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HFS4045120.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATF
                     EAKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFPGYGKGLAPTTQFDVLIHILSLR
                     HDVNFSVAQAAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMMIGRTKEANEEIDGDERPETSHLTR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDKLMAL"
     gene            complement(16020..17321)
                     /gene="pbp4b"
                     /locus_tag="ACHY1N_002832"
     CDS             complement(16020..17321)
                     /gene="pbp4b"
                     /locus_tag="ACHY1N_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015674721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin binding protein PBP4B"
                     /protein_id="HFS4045121.1"
                     /translation="MKRTMLYLSLLAVSCSVSAAKYPVLTESSPEKAGFNVERLNQMD
                     RWISQQVDAGYPGVNLLIIKDNQIVYRKAWGAAKKYDGSVLMEQPVKATTGTLYDLAS
                     NTKMYATNFALQKLMSEGKLHPDDRIAKYIPGFADSPNDTIKGKNTLRISDLLHHSGG
                     FPADPQYPNKAVAGALYSQDKGQTLEMIKRTPLEYQPGSKHIYSDVDYMLLGFIVESV
                     TGQPLDRYVEESIYRPLGLTHTVFNPLLKGFKPQQIAATELNGNTRDGVIHFPNIRTS
                     TLWGQVHDEKAFYSMGGVSGHAGLFSNTGDIAVLMQTMLNGGGYGDVQLFSAETVKMF
                     TTSSKEDATFGLGWRVNGNATMTPTFGTLASPQTYGHTGWTGTVTVIDPVNHMAIVML
                     SNKPHSPVADPQKNPNMFESGQLPIATYGWVVDQVYAALKQ"
     gene            complement(17326..18750)
                     /gene="murP"
                     /locus_tag="ACHY1N_002833"
     CDS             complement(17326..18750)
                     /gene="murP"
                     /locus_tag="ACHY1N_002833"
                     /EC_number="2.7.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylmuramic acid transporter subunit
                     IIBC"
                     /protein_id="HFS4045122.1"
                     /translation="MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVD
                     PNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQL
                     KAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALN
                     FMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDF
                     FGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIM
                     PLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNS
                     LFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMK
                     PFITACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAG
                     GILVAWVCGFIFTTLFGCRNVNLD"
     gene            complement(18754..19650)
                     /gene="murQ"
                     /locus_tag="ACHY1N_002834"
     CDS             complement(18754..19650)
                     /gene="murQ"
                     /locus_tag="ACHY1N_002834"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFS4045123.1"
                     /translation="MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERV
                     LPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGG
                     EYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
                     TVGISCNPGSAVSTTAEFAITPIVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGK
                     VFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLD
                     AAEAKKRLDQHGGFIRQVLDKE"
     gene            19814..20671
                     /gene="murR"
                     /locus_tag="ACHY1N_002835"
     CDS             19814..20671
                     /gene="murR"
                     /locus_tag="ACHY1N_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MurR"
                     /protein_id="HFS4045124.1"
                     /translation="MLYLTKIRNAESEFTENEQKIADFLRANVSELKSVSSRKMAKQL
                     GISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIA
                     RKLNREKELALEQTCALFDYARLQKIIDVISKAQFIQITGLGGSALVGRDLSFKLMKI
                     GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSL
                     ADSPLRRLAHFTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQR
                     SSELTQRLK"
     gene            20800..21591
                     /gene="ucpA"
                     /locus_tag="ACHY1N_002836"
     CDS             20800..21591
                     /gene="ucpA"
                     /locus_tag="ACHY1N_002836"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416921.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HFS4045125.1"
                     /translation="MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEK
                     LADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMS
                     DEDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAIPM
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPETVSVGI"
     gene            21762..22778
                     /gene="cysP"
                     /locus_tag="ACHY1N_002837"
     CDS             21762..22778
                     /gene="cysP"
                     /locus_tag="ACHY1N_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate/sulfate ABC transporter
                     substrate-binding protein CysP"
                     /protein_id="HFS4045126.1"
                     /translation="MAVNLLKKNSLALVASLLLAGHVQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADKADGGDKGKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQA
                     QTIITDYYYRVNNPEVMDKLKNKFPQTELFRVEDKFGSWPEVMKTHFTSGGELDKLLA
                     AGRN"
     gene            22778..23611
                     /gene="cysT"
                     /locus_tag="ACHY1N_002838"
     CDS             22778..23611
                     /gene="cysT"
                     /locus_tag="ACHY1N_002838"
                     /EC_number="7.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HFS4045127.1"
                     /translation="MFAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLAQMSW
                     AQYWEVITNPQVVAAYKVTLLSAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGEWLAKFDIKVTYTLLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAETLGATRWQSFCKVVLPELSPALVAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVG
                     H"
     gene            23611..24486
                     /gene="cysW"
                     /locus_tag="ACHY1N_002839"
     CDS             23611..24486
                     /gene="cysW"
                     /locus_tag="ACHY1N_002839"
                     /EC_number="7.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HFS4045128.1"
                     /translation="MAEVTQLKRYDARPINWGKWFLIGIGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEEHHEH"
     gene            24476..25573
                     /gene="cysA"
                     /locus_tag="ACHY1N_002840"
     CDS             24476..25573
                     /gene="cysA"
                     /locus_tag="ACHY1N_002840"
                     /EC_number="7.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HFS4045129.1"
                     /translation="MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRERPNAAAIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPNQVWREPATRFVLEFMGEVNRLQGTIRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYNEPLTVVMHGDDAPQRGE
                     RLFVGLQHARLYNGDERIETRDEELALAQSA"
     gene            25707..26618
                     /gene="cysM"
                     /locus_tag="ACHY1N_002841"
     CDS             25707..26618
                     /gene="cysM"
                     /locus_tag="ACHY1N_002841"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase B"
                     /protein_id="HFS4045130.1"
                     /translation="MSTLEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQ
                     QTGGRITHFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPAEYLP
                     GIFNASLVDEVLDIHQRDAENTMRELAVREGIFCGVSSGGAVAGALRVAKANPGAVVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(26621..26989)
                     /locus_tag="ACHY1N_002842"
     CDS             complement(26621..26989)
                     /locus_tag="ACHY1N_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001592994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HFS4045131.1"
                     /translation="MKKIICLVITLLMTLPAYAKLTAHEEARINAMLEGLAQKKDLIF
                     VRNGDEHTCDEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKIPGKSDE
                     NAQPFLHALIAQTDKTVPAQ"
     gene            27094..27945
                     /gene="pdxK"
                     /locus_tag="ACHY1N_002843"
                     /gene_synonym="thiJ"
     CDS             27094..27945
                     /gene="pdxK"
                     /locus_tag="ACHY1N_002843"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HFS4045132.1"
                     /translation="MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGL
                     NVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQ
                     IKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
                     FELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNV
                     ISHSRVKTDLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELI
                     LPPLAEA"
     gene            complement(27987..28496)
                     /gene="crr"
                     /locus_tag="ACHY1N_002844"
     CDS             complement(27987..28496)
                     /gene="crr"
                     /locus_tag="ACHY1N_002844"
                     /EC_number="2.7.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFS4045133.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIIAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(28537..30264)
                     /gene="ptsI"
                     /locus_tag="ACHY1N_002845"
     CDS             complement(28537..30264)
                     /gene="ptsI"
                     /locus_tag="ACHY1N_002845"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HFS4045134.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFL
                     SGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
                     ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYL
                     ILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAIRIAMDRKEILRDQLRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            complement(30309..30566)
                     /gene="ptsH"
                     /locus_tag="ACHY1N_002846"
     CDS             complement(30309..30566)
                     /gene="ptsH"
                     /locus_tag="ACHY1N_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HFS4045135.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            complement(30950..31921)
                     /gene="cysK"
                     /locus_tag="ACHY1N_002847"
     CDS             complement(30950..31921)
                     /gene="cysK"
                     /locus_tag="ACHY1N_002847"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFS4045136.1"
                     /translation="MSKIFEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFIAGVGTGGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPANLDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
     gene            complement(32106..32867)
                     /gene="cysZ"
                     /locus_tag="ACHY1N_002848"
     CDS             complement(32106..32867)
                     /gene="cysZ"
                     /locus_tag="ACHY1N_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015116 - sulfate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HFS4045137.1"
                     /translation="MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMG
                     GAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAP
                     FNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYLIP
                     GIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSL
                     FTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR"
     gene            33097..34083
                     /gene="zipA"
                     /locus_tag="ACHY1N_002849"
     CDS             33097..34083
                     /gene="zipA"
                     /locus_tag="ACHY1N_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HFS4045138.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPR
                     QPVQQPPEAQVPPQHAPRPAQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPA
                     QQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQ
                     AGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYG
                     DELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA"
     gene            34154..36169
                     /gene="ligA"
                     /locus_tag="ACHY1N_002850"
     CDS             34154..36169
                     /gene="ligA"
                     /locus_tag="ACHY1N_002850"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFS4045139.1"
                     /translation="MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRE
                     LETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KNNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEED
                     RPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAE
                     ESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVEL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS"
     gene            36171..36389
                     /locus_tag="ACHY1N_002851"
     CDS             36171..36389
                     /locus_tag="ACHY1N_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HFS4045140.1"
                     /translation="MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAG
                     KLGELMQITLLIKTEGLTQLVQPLKRPL"
     gene            complement(36386..37384)
                     /locus_tag="ACHY1N_002852"
     CDS             complement(36386..37384)
                     /locus_tag="ACHY1N_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="HFS4045141.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPARGDFVPFFENLTTAAIAL
                     LFFMHGAKLSREAIIAGGGHWRLHLWVICSTFVLFPILGVLFAWWKPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNVHGAGGS
                     LEQVGKIMLQLLLPFVLGHLSRPWIGDWVSRNKKWIAKTDQTSILLVVYTAFSEAVVN
                     GIWHKVGWGSLLFIVVVSCVLLAIVIVVNVFMARRLGFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKRQTEQLQAQQESSTDKA"
     gene            37474..38400
                     /locus_tag="ACHY1N_002853"
     CDS             37474..38400
                     /locus_tag="ACHY1N_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4045142.1"
                     /translation="MNYSLKQLKVFVTVAQEKSFSRAGERIGLSQSAVSHSVKELENH
                     TGVRLLDRTTREVVLTDAGQQLALRLERLLDELNSTLRDTGRMGQQLSGKVRVAASQT
                     ISAHLIPQCIAESHRRYPDIQFVLHDRPQQWVMESIRQGDVDFGIVIDPGPVGDLQCE
                     AILSEPFFLLCHRDSALAVEDYVPWQALQGAKLVLQDYASGSRPLIDAALARNGIQAN
                     IVQEIGHPATLFPMVAAGIGISILPALALPLPEGSPLVVKRITPVVERQLMLVRRKNR
                     SLSTAAEALWDVVRDQGNALMAGREGDPLYQI"
     gene            complement(38439..39203)
                     /locus_tag="ACHY1N_002854"
     CDS             complement(38439..39203)
                     /locus_tag="ACHY1N_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpK"
                     /protein_id="HFS4045143.1"
                     /translation="MKKHLLTLTLSSILAIPVVSHAEFKGGFADIGVHYLDWTSRTTE
                     KSSTKSHKDDFGYLEFEGGANFSWGEMYGFFDWENFYNGRHNKPGSEQRYTFKNTNRI
                     YLGDTGFNLYLHAYGTYGSANRVNFHDDMFLYGIGYNFTGSGWWFKPFFAKRYTDQTY
                     YTGDNGYVAGWVAGYNFMLGSEKFTLTNWNEYEFDRDATYAAGNGGKEGLNGAVALWW
                     NATSHITTGIQYRYADDKLGEDFYQDAIIYSIKFNF"
     gene            39452..40285
                     /gene="xapA"
                     /locus_tag="ACHY1N_002855"
     CDS             39452..40285
                     /gene="xapA"
                     /locus_tag="ACHY1N_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0055086 - nucleobase-containing small
                     molecule metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine phosphorylase"
                     /protein_id="HFS4045144.1"
                     /translation="MSQVQFSHNPLFCIDIIKTYKPDFTPRVAFILGSGLGALADQIE
                     NAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIR
                     TFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSL
                     ANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV
                     PEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI
                     A"
     gene            40345..41601
                     /gene="xapB"
                     /locus_tag="ACHY1N_002856"
     CDS             40345..41601
                     /gene="xapB"
                     /locus_tag="ACHY1N_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine/proton symporter XapB"
                     /protein_id="HFS4045145.1"
                     /translation="MSIAMRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVY
                     SSKGIAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGVLFYAASVTDPDMMFWVMLVN
                     AMAFMPTIALSNSVSYSCLAQAGLDPVTAFPPIRVFGTVGFIVAMWAVSLLHLELSSL
                     QLYIASGASLLLSAYALTLPKIPVAEKKATTSLASKLGLDAFVLFKNPRMAIFFLFAM
                     MLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLK
                     RFGIKTVMLMSMVAWTLRFGFFAYGDPSTTGFILLLLSMIVYGCAFDFFNISGSVFVE
                     QEVDSSIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFSVDGVKDWQTIWLVFAGYAL
                     FLAVIFFFGFKYNHDPEKIKHRAVAH"
     gene            41654..41812
                     /locus_tag="ACHY1N_002857"
     CDS             41654..41812
                     /locus_tag="ACHY1N_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1427 family protein"
                     /protein_id="HFS4045146.1"
                     /translation="MKDILFSSGVGFGIGALFTIVRLPIPVPNVLPGILSIVFMYVGY
                     LVVKYFMQ"
     gene            41853..42737
                     /gene="xapR"
                     /locus_tag="ACHY1N_002858"
     CDS             41853..42737
                     /gene="xapR"
                     /locus_tag="ACHY1N_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XapR"
                     /protein_id="HFS4045147.1"
                     /translation="MERVYRTDLKLLRYFLAVAEELHFGRAAARLNMSQPPLRIHIKE
                     LENQLGTQLFIRHSRSVVLTHAGKILMEESRRLLVNANNVLARVEQIGRGEAGRIELG
                     VVGTAMWGRMRPVMRRFLRENPNVEVLFREKMPAMQMALLERRELDAGIWRMATEPPT
                     GFTSLRLHESAFLVAMPEEHHLSSFSTVPLEALRDEYFVTMPPVYTDWDFLQRVCQQV
                     GFSPVVIREVNEPQTVLAMVSMGIGITLIADSYAQMNWPGVIFRPLKQRIPADLYIVY
                     ETQQVTPAMVKLLAALTQ"
     gene            complement(42846..42921)
                     /locus_tag="ACHY1N_002859"
     tRNA            complement(42846..42921)
                     /locus_tag="ACHY1N_002859"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42886..42888),aa:Lys,seq:ttt)
     gene            complement(42926..43001)
                     /locus_tag="ACHY1N_002860"
     tRNA            complement(42926..43001)
                     /locus_tag="ACHY1N_002860"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42966..42968),aa:Val,seq:tac)
BASE COUNT        10037 a        10831 c        11964 g        10171 t
ORIGIN      
        1 gttgaatgaa cggtcccgtt ctggaccctg ataaagagga aagcacaatg gaagcattag
       61 gaatgatcga aacccggggc ctggttgcac tgattgaggc ttctgacgcg atggtgaaag
      121 ctgcgcgcgt caagctggtt ggtgttaagc agattggcgg cggcctgtgt actgccatgg
      181 ttcgtggtga tgttgcagcc tgtaaagccg cgaccgatgc aggtgccgca gcggcacagc
      241 gtatcggcga gctggtatct gtacacgtta tcccgcgtcc gcacggcgac ctggaagaag
      301 tcttcccgat cggcctgaaa ggcgatagca gcaacctgta atcaccctgt gtgacgtcga
      361 ttcgggcgtc acgctctctc ctttttcatt ttaccttctg cggagggtag ggggagcttt
      421 tacctgaaat acgccacgga ggcgggtatg aaactggcag tcgtcactgg acaaattgtt
      481 tgtaccgtac gccatcacgg actggcgcat gacaaattgc tgatggtgga aatgattgat
      541 ccacaaggta atcctgacgg gcaatgcgcc gtcgccatcg acaatattgg cgcgggaacc
      601 ggggagtggg tgttactggt gagtggcagt tccgcccgcc aggcgcataa aagcgaaacg
      661 tcaccggtcg atctgtgcgt gattggcatt gtcgatgagg tggtgtctgg cggtcaggta
      721 attttccaca aataaggcag aacatcatga atcaacagga tattgaacag gtggtgaaag
      781 cggtactgct gaaaatgcaa agcagtgaca cgccgtccgc cgccgttcat gagatgggcg
      841 ttttcgcgtc cctggatgac gccgttgcgg cagccaaagt cgcccagcaa gggttaaaaa
      901 gcgtggcaat gcgccagtta gccattgctg ccattcgtga ggcaggcgaa aaacacgcca
      961 gagatttagc ggaacttgcc gtcagtgaaa ccggcatggg ccgcgttgaa gataaatttg
     1021 ccaaaaacgt cgctcaggcg cgcggcacgc caggcgttga gtgtctctct ccgcaggtgc
     1081 tgaccggcga caacggcctg actttaattg aaaacgcgcc ctggggcgtg gtggcttcgg
     1141 taactccgtc cactaacccg gcggcaaccg taattaataa cgccatcagc ctgattgccg
     1201 cgggcaacag cgtcattttt gccccgcatc cggcggcgaa aaaagtctcc cagcgggcga
     1261 ttacgctgct caaccaggcg attgttgccg caggtgggcc ggaaaactta ctggttactg
     1321 tggcaaatcc ggatatcgaa accgcgcaac gcttgttcaa gtttccgggt atcggcctgc
     1381 tggtggtaac cggcggcgaa gcggtagtag aagcggcgcg taaacacacc aataaacgtc
     1441 tgattgccgc aggcgctggc aacccgccgg tagtggtgga tgaaaccgct gacctcgccc
     1501 gtgctgctca gtccatcgtc aaaggcgcgt ctttcgataa caacatcatt tgtgccgacg
     1561 aaaaggtact gattgttgtt gatagcgtag ccgatgaact gatgcgtctg atggaaggcc
     1621 agcacgcggt gaaactgacc gcagaacagg cgcagcagct gcaaccggtg ttgctgaaaa
     1681 atatcgacga gcgcggaaaa ggcaccgtca gccgtgactg ggttggtcgc gatgcggcga
     1741 aaatcgcggc ggcaatcggc ctgaacgtgc cgcaagaaac gcgtttgctg tttgtggaaa
     1801 ccactgcaga acatccgttt gccgtgaccg aactgatgat gccggtgctg cccgtcgtgc
     1861 gcgtcgccaa cgtggcggat gccattgcgc tggcggtgaa actggaaggc ggttgccacc
     1921 acacggcggc aatgcactcg cgcaacatcg aaaacatgaa ccagatggcg aatgctattg
     1981 ataccagcat tttcgttaag aacggaccgt gcattgccgg gctggggctg ggcggggaag
     2041 gctggaccac catgaccatc accacgccaa ccggtgaagg ggtaaccagc gcgcgtacgt
     2101 ttgtccgtct gcgtcgctgt gtattagtcg atgcgtttcg cattgtttaa ggagtaacag
     2161 atggcgcacg acgaacaatg gctcacccca cgtctgcaaa cggcggcaac gctgtgtaac
     2221 cagacgcccg ccgcgacgga atctccgctg tggctggggg tggatctggg cacctgcgat
     2281 gtggtgtcga tggttgtcga ccgcgacggt cagccggtgg cggtatgcct cgactgggcc
     2341 gatgtggtcc gcgacggcat cgtctgggat ttcttcggcg ctgtcaccat tgttcgtcgc
     2401 catctcgaca cgctcgagca gcaattcggt cgccgtttta gccatgcggc gacttcattt
     2461 cctccaggta cggacccgcg tatttccatc aacgtgctgg agtctgccgg gctggaagtg
     2521 agccatgtgc tggatgagcc aaccgcagtc gcggatctac tgcaactgga taacgcaggc
     2581 gtagtggata tcggcggtgg cactaccggc attgccatcg tgaaaaaggg caaagtgacg
     2641 tactcggcgg atgaagccac cggcggacat cacatctctc tgactctcgc cggaaatcgc
     2701 cgtatttcgc tggaagaggc ggagcagtac aagcgcggtc acggtgacga gatttggcct
     2761 gcggtgaaac cggtgtacga aaaaatggcg gacattgtcg cccggcatat tgaagggcag
     2821 ggcattactg atttatggct ggcgggcggc tcctgtatgc aaccgggcgt ggcagaactg
     2881 tttcgcaaac aattcccggc gttacaggtg catttaccgc agcacagttt gtttatgacc
     2941 ccgctggcga tcgccagtag tgggcgagag aaagcggagg ggctatatgc aaaatgaatt
     3001 gcagaccgcg ctctttcagg cgttcgatac cctgaatctg caacgggtaa aaacatttag
     3061 cgttccaccg gtgacgcttt gcggtctggg cgcggtgagc agttgcgggc agcaagcgca
     3121 aacgcgtggg ctgaaacatc tgttcgtgat ggcagacagc tttttgcatc aggcagggat
     3181 gaccgccggg ctgacgcgca gcctggccgt taaaggcatc gccatgacgc tctggctatg
     3241 tccggtgggc gaaccgtgca ttaccgacgt gtgtgcagcc gtggcgcagt tgcgtgagtc
     3301 aggttgtgac ggggtgatcg catttggcgg cggctcggtg ctggatgcgg cgaaagccgt
     3361 ggcgttgctg gtgacgaacc cggatagcac gctggcagag atgtcagaaa ccagcgttct
     3421 gcaaccgcgc ttgccgctga ttgccattcc aactaccgcc ggaaccggct ctgaaaccac
     3481 caatgtaacg gtgattatcg acgcggtgag cgggcgcaag caggtgttag cccatgcctc
     3541 gctgatgccg gatgtggcga tcctcgacgc cgcattgacc gaaggtgtgc cgtcgcatgt
     3601 cacggcgatg accggcattg atgcgttaac ccatgccatt gaagcataca gcgccctgaa
     3661 cgctacaccg tttaccgaca gtctggcgat tggtgccatt gcgatgattg gcaaatcgct
     3721 gccgaaagcg gtgggctacg gtcacgacct tgccgcgcgc gagagcatgt tgctggcttc
     3781 atgtatggcg ggaatggcgt tttccagtgc gggtcttggg ttgtgccacg cgatggcgca
     3841 tcagccgggc gcggcgctgc atattccaca cggtctggcg aacgccatgt tgctgccaac
     3901 ggtgatggaa tttaaccgga tggtttgtcg cgaacggttt agtcagattg gtcgggcact
     3961 gcgaactaaa aaatccgacg atcgtgacgc tattaacgcg gtaagtgagc tgattgcgga
     4021 agttgggatt ggtaaacgac tgggcgatgt tggcgcgaca tctgcgcatt acggtgcatg
     4081 ggcgcaggcc gcgcaggaag atatttgtct gcgcagcaac ccgcgtaccg ccagcctgga
     4141 acaaattgtc ggactgtacg cggcggcgca ataaatgccg gatgcgacgc ttgccgcgtc
     4201 ttatccggcc tacgggattg cacatgtagg gcggataagg cgtttacgcc gcatccgcca
     4261 ataaataaca actaacaggg agtaaaggcg atgggaatta acgaaatcat catgtacatc
     4321 atgatgttct ttatgctgat agctgccgta gacaggatcc tgtcgcagtt cggcggttct
     4381 gctcgtttcc tcggtaagtt cggtaaaagt atcgaaggat caggcggtca gttcgaagaa
     4441 ggctttatgg caatgggcgc tctgggtctg gcgatggtcg gtatgaccgc gctggcaccg
     4501 gtactggctc acgtactcgg gccggtaatt atcccggttt acgaaatgct cggcgcaaac
     4561 ccgtcaatgt tcgccggaac actgctggcg tgcgatatgg gcggcttctt cctcgccaaa
     4621 gagctggcgg gcggcgacgt agcagcgtgg ctatactctg ggttaattct cgggtcgatg
     4681 atggggccaa cgattgtgtt ttccattccg gtggcgctcg gcattatcga accttctgat
     4741 cgtcgttatc tggcgctcgg cgtgctggcg ggcattgtga ccattccgat tggctgtatt
     4801 gctggtggtc tggttgctat gtactccggt gtgcagatca acggtcagcc ggtggaattc
     4861 actttcgccc tgatcctgat gaacatgatc ccggtgatca ttgtcgcgat tctggtggcg
     4921 ctggggctga aattcatccc ggaaaaaatg atcaacggct tccagatctt tgccaaattc
     4981 ctcgttgcat tgatcaccct cggtcttgcc gctgcggtag tgaaattcct ccttggctgg
     5041 gaactgatcc ccggactgga tcctatcttt atggcccctg gcgataaacc cggtgaagtg
     5101 atgcgcgcca ttgaagttat cggttctatc tcctgcgtgc tgttaggggc gtatccaatg
     5161 gtgctgctgc tgactcgctg gtttgaaaaa ccgctgatga gcgtcggtaa agtactgaat
     5221 atgaacaaca tcgcggcagc cggcatggtg gcaacgcttg ccaacaacat cccgatgttc
     5281 ggcatgatga agcagatgga tacccgcggc aaagtcatca actgcgcctt cgccgtttcc
     5341 gctgctttcg ccctgggcga ccacttaggc ttcgccgctg ccaacatgaa cgccatgatc
     5401 ttcccgatga ttgtcggcaa gttgatcggc ggcgtaacgg cgattggcgt ggcgatgatg
     5461 ctggtgccaa aagaagacgc gaccgcgact aaaaccgaag cggaggcaca atcgtgaaca
     5521 ctcgccagct attgagcgtc ggtatcgata tcggcaccac caccacccag gtgattttct
     5581 cccacctgga actggttaac cgtgcggcgg tgtcgcaggt gccgcgctac gaattcatta
     5641 aacgcgaaat tagctggcaa agcccggtat tctttacccc tgtcgataaa cagggtggtt
     5701 taaaagaagc ggaactgaaa tcgctgattt tagagcaata tcaggctgcg ggcattgcgc
     5761 cggaaagcgt tgattctggt gccatcatca tcaccggtga aagcgcgaaa acccgcaatg
     5821 ctcgcccggc ggtgatggcg ctctctcagt cgctgggcga ttttgtcgtt gccagcgccg
     5881 ggccgcacct cgaatccgtg atcgccggtc acggagccgg ggcacaaacc ctttctgaac
     5941 aacggctgtg tcgggtactg aatatcgaca tcggcggtgg caccgcgaac tacgccctgt
     6001 tcgatgccgg aaaaatcagc ggcactgcct gtctcaacgt cggtggtcgc ctgctggaaa
     6061 ccgacagcca ggggcgcgtg gtttacgctc ataaaccggg gcagatgatt gtggatgagt
     6121 gcttcggtgc aggcactgac gcccgttcgc tgaccggcgc gcagctggtg caggttaccc
     6181 ggcggatggc ggcgctgatt gtcgaagtga ttgacggaac gctttcgccg ctcgcgcagg
     6241 cattgatgca aaccggtttg ctgcccgcag gtgttacgcc cgaaatcatt acgctttctg
     6301 gaggcgtggg cgaatgttat cgccaccagc ccgccgaccc gttctgtttt gccgatattg
     6361 gcccacttct ggcaacggcg ctgcatgacc atccgcgcct gcgtgagatg aatgtgcagt
     6421 ttccggcgca aaccgtacgc gccacggtga ttggcgcggg tgcacatacc ctttcgctct
     6481 ctggcagcac aatctggctg gagggcgtac aactgccgct gcgcaatttg ccggtggcga
     6541 tcccgattga tgaaacggat ctggtgagtg cctggcaaca ggcgctgctt cagctggatc
     6601 ttgatcccaa aactgacgcg tacgtgctgg cgcttcccgc ctcgctgcct gtgcgttacg
     6661 ccgcggtact gacggtcatc aacgcgctgg tcgatttcgt cgcgcgtttt ccgaatccgc
     6721 atcccctgct ggtggtggcc gggcaggact ttggtaaagc tctgggcatg ttgttgcgcc
     6781 cacagctaca acaactcccg ttggcagtca ttgacgaagt gattgtccgc gcgggggact
     6841 atatcgacat tggtacgcct ctttttggcg gatcggttgt gccggtgacg gtgaaatcac
     6901 tcgcatttcc ttcctgaggg aacgacttat gaaactaaag accacattgt tcagcaatgt
     6961 atatcagttt aaggatgtaa aagaggtgct ggctaaagcc aacgaactgc gttcggggga
     7021 tgtgctggca ggcgttgcag cggcaagttc acaggagcgc gtggcggcaa agcaggtgtt
     7081 gtcggaaatg accgtagcgg acatccgcaa taatccggtg attgcctatg aagatgactg
     7141 cgtgacgcgg ctgattcagg acgatgttaa cgaaacggcc tacaaccaga ttaaaaactg
     7201 gagcatcagc gaactgcgtg agtatgtgct gagcgatgaa accagcgtgg acgacattgc
     7261 ctttacccgc aaagggctga cctcggaagt ggtcgcggcg gtagcgaaga tttgctccaa
     7321 cgcggacctg atctacggcg cgaagaaaat gccggtaatc aaaaaggcca ataccaccat
     7381 tggtattccg ggcaccttca gcgcccgttt gcagccaaat gacacccgtg acgacgtgca
     7441 aagtatcgcc gcgcaaatct acgaagggct ttccttcggg gtgggcgatg cggtgatcgg
     7501 cgttaacccg gtgactgacg acgtggaaaa cttaagccgc gtgttggaca ccatttacgg
     7561 cgtgatcgac aaattcaaca tcccaactca gggctgcgta ctggcgcacg tcaccaccca
     7621 gatcgaagcg attcgtcgcg gcgcgcctgg cggactgatt ttccagagta tctgtggcag
     7681 cgaaaaaggg ctgaaagagt ttggcgtgga actggcgatg ctcgacgaag cgcgcgcagt
     7741 gggtgcagag ttcaaccgta tcgccgggga aaactgcctc tacttcgaaa ccggacaagg
     7801 ctctgcgcta tccgctggcg ctaacttcgg cgctgaccag gtgacgatgg aagcacgtaa
     7861 ctatgggctg gcgcgtcatt acgatccgtt tatcgtcaac accgtggtcg gctttattgg
     7921 gccggagtat ctctacaacg accgccagat tatccgtgct ggcttagaag atcactttat
     7981 gggcaagctg agcggcatct ctatgggctg tgactgctgt tacaccaacc acgctgacgc
     8041 tgaccagaac ctcaacgaaa acctgatgat cctgctcgcc accgcaggct gcaactacat
     8101 catggggatg ccgctgggtg atgacatcat gctcaactac cagaccaccg cattccacga
     8161 taccgccact gtgcgtcagt tactcaacct gcgtccgtca ccggagtttg aacgctggct
     8221 ggaaagcatg ggcattatgg caaacggtcg cctgaccaaa cgggcgggcg atccgtcact
     8281 gttcttctga tgacgcggag ataacacatc atggatcaaa aacagattga agaaattgta
     8341 cgcagcgtga tggcgtcaat gggacaaacg gcccccgcgc cgtcagaagc aaagtgcgcc
     8401 accaccaact gtgcggcacc ggtgacctcg gaaagctgtg cgctggattt aggttccgct
     8461 gaagcaaaag cgtggattgg tgttgaaaac ccgcatcgcg cagacgtatt aacagaactg
     8521 cgccgcagca ccgtggcccg cgtttgtacc ggtcgtgccg gtccgcgtcc acgtacccag
     8581 gcgctgctgc gtttcctggc cgatcactct cgttcgaaag ataccgtact gaaagaagtg
     8641 ccggaagagt gggtgaaagc gcagggcttg ctggaagtac gctctgaaat tagcgacaaa
     8701 aatctctacc tgactcgccc ggatatgggc cgccgcctgt gtgcagaagc tgttgaagcg
     8761 ctgaaagcac agtgtgttgc taatccggac gtacaggtcg ttatttctga tggcctgtca
     8821 actgatgcca tcaccgtgaa ctacgaagag atcctgccgc cgctgatggc gggcctgaaa
     8881 caggccgggc tgaaagtcgg cacgccattc tttgttcgtt atggtcgcgt gaagattgaa
     8941 gatcagatcg gtgagatcct cggcgcgaaa gtggtgatcc tgctggtggg ggaacgtccg
     9001 gggttagggc agtcagaaag cctctcctgc tacgccgttt actcgccgcg tatggcgacc
     9061 accgttgagg ccgatcgcac ctgtatctct aacattcacc agggcggcac gccgccggtt
     9121 gaagccgcag ccgtcattgt ggatttggcg aaacgtatgc tggagcagaa agcatccggc
     9181 atcaacatga cccgataagg aggcatcatg ccagctttag atttgattcg accgtcggta
     9241 accgccatgc gggtgattgc ctccgttaac gctgaatttg cgcgtgaact aaaattgccg
     9301 ccgcatattc gtagcctcgg gctgatttct gctgattccg atgacgtcac ctacattgcc
     9361 gctgatgaag cgaccaagca ggcgatggtg gaagtggtat atggtcgctc gctgtatgcg
     9421 ggcgctgcac acggcccgtc accgactgcc ggtgaagtgc tgattatgct tggtgggcca
     9481 aacccggcgg aagtgcgtgc cggtctggat gcgatggttg cacatattga aaatggtgca
     9541 gcattccagt gggccaatga cgcagaaaac accgccttcc tggcgcatgt ggtttcgcgt
     9601 accggttctt atctctcatc aaccgccggg atcacgcttg gcgatccgat ggcgtatctg
     9661 gtggcaccgc cgctggaagc gacctatggc attgatgcag cgttgaaatc tgccgacgta
     9721 cagctggtga cctatgtccc gccaccgtct gaaaccaact actcggcagc atttttaacc
     9781 ggtagccagg ccgcgtgtaa agcagcctgt aacgccttta ccgatgcagt gctggaaatc
     9841 gcgcgtaatc caatccagcg tgcgtaacgg aggttgccga tgatcaatgc actgggattg
     9901 ctggaagtgg acggcatggt cgccgcgata gatgcagcgg atgccatgct caaagcagct
     9961 aacgttcgtc tgctcagtca cgaagtgctt gaccctggtc gcttaacgct ggtggtggaa
    10021 ggcgatctgg cggcgtgtcg tgcggcgctg gacgcaggtt gtgctgccgc gatgcgtacc
    10081 gggcgtgtca tcagccgcaa ggagatcggt cggccagacg atgacaccca gtggctggtt
    10141 actggcttta accgccagcc gaagcaaccc gtaagggaac ccgacgcgcc agttatcgtc
    10201 gcggaatctg ctgacgagtt gttggcgctg ttaacatcag tacgtcaggg aatgacggca
    10261 ggagaagtgg ctgcccactt tggctggccg ctggaaaaag ccagaaatgc gctcgaacag
    10321 ctcttttctg ccgggacgtt acgtaaacgc agtagtcgtt atcgtctcaa gccccattaa
    10381 cctgtcggag gtgccgggtg tcctacaaca cccggcatta acatcatgaa aaagacccgt
    10441 acagccaatt tgcaccatct ttatcatgaa cccttacccg aaaacctgaa gctcacgccg
    10501 aaggtcgaag tggataatgt tcatcaacga cagacaacgg atgtctatga acatgcttta
    10561 acgattaccg cctggcagca gatttacgat cagctgcatc cgggcaagtt tcatggtgaa
    10621 tttacggaaa ttctactcga tgatattcag gtttttcgtg aatacaccgg tctggcgctg
    10681 cgtcagtcgt gcctggtctg gccgaactcg ttctggtttg gcattccggc gacgcgcggt
    10741 gagcagggat ttatcggttc gcaatgtctg ggaagcgcgg aaatcgccac ccgccctggt
    10801 ggcactgaat ttgaactgag cacgccggat gattacacga tcctgggcgt ggtgctttct
    10861 gaagatgtca tcacccgaca ggctaacttt ttgcataacc cggatcgggt attacatatg
    10921 ctgcgtagcc agtcggcgct ggaagtgaaa gagcagcata aagccgcgct gtggggcttt
    10981 gtccaacagg cgctggcgac gttttgcgag aacccggaaa atctccatca gcctgcagtg
    11041 cgaaaagtgc tgggggataa tttgctaatg gcgatggggg cgatgctgga agacgcgcaa
    11101 ccaatggtga cggcggaaag catcagtcat cagagttacc gtagattact ttcccgcgcc
    11161 cgtgaatatg tgctggaaaa tatgtctgag ccggtgacgg tgctggactt gtgtaatcaa
    11221 ctgcatgtca gtcgccgcac gctacaaaac gcgtttcacg ctattttagg cattggccca
    11281 aacgcgtggc tgaaacgcat tcgcctgaac gccgtacgcc gcgaactgat aagcccgtgg
    11341 tcgcaaagca caacggtaaa agacgccgcc atgcagtggg gattctggca tctggggcaa
    11401 tttgccacgg attaccagca gctgtttgcc gagaagccgt cgttgacgtt gcatcagcgg
    11461 atgcgggaat gggggtgagg gagttacacc caatccctga ccttaataaa ctcacttaac
    11521 gccgcttctg ggctgccatc ttttggctga taatcatact cccagcgtac cagtggcggc
    11581 attgacatca ggatcgactc ggtgcgcccg ccagtttgca ggccaaacag agtgccgcga
    11641 tcccagacca gattgaactc gacataacga ccgcgacggt agagctgaaa attgcgctcg
    11701 cgctcgccgt aggccatcgc tttacgtcgc tctacaattg gtaaataagc gtcggtgtag
    11761 cctttgccta ccgcctgcat aaaggcaaaa cagtggtcga aatctggcgt gttcagatca
    11821 tcaaagaaca gcccgccaat accgcgctgt tcgttgcgat gtttgaggta gaagtaatcg
    11881 tcgcaccact ttttgtaacg gggataaacg tcttcaccaa atggcaggca caggtcacgg
    11941 gcggtgcggt gccagtgaat ggcgtcttct tcaaaaccat agaaaggggt taaatcgaag
    12001 ccgccgccaa accaccagac gggctctgca cccggttttt cggcaataaa aaaacgcaca
    12061 ttcgcgtggc tggtgggaac atacgggtta tgcggatgca ctaccagtga aacgcccatc
    12121 gcctcgaaac tgcgcccggc aagttccggg cgatgagcgg tggcggaagc tggcatcgcc
    12181 tcgccgtgga cgtgagaaaa gttgacgcct gcctgttcga aaacaccacc attacgcaac
    12241 acccgactac gcccgccgcc gccagcttcg cgctgccaac tatcttcgac aaattctgcg
    12301 ccatcgacgg cggtcagctg ctgacaaatc gtatcctgaa ggttgagcag aaactgttta
    12361 acctggtgtg cgtcgggttt cataacttat cgctttttcg aatgtgcttt ctggttgtcg
    12421 aaccagtgga aataactgat cacgccttca gcaatcgctg tggcgatttt ctgacgaaac
    12481 gccgccgtgc ctaacagccg ctcttcttcc gggttggtga taaacgaggt ttccaccagc
    12541 accgaaggaa ccgacggcga tttcaacacc acaaacgcgg cttgttcggt gttgcggctg
    12601 tgcagtttat gcaccggctt aatctttttc agaatatgcg agccgagcgt caggctgttt
    12661 ttaatagtat cggtttgcac cagatcaaac agcacttgct gcaataggtg atccttgtca
    12721 gtcgcctttt taccggcaac ttcatcggcg cggttttcgc gttcagacag gtatttcgcc
    12781 attgcgctac ttgccccacg gttagagagg gcaaataccg aagcaccggc agctttcggg
    12841 ttggtaaagc catcggcatg aattgacata aacagatctg cgccatgttt atgggcgatt
    12901 tcaacgcgat cgtaaagtgg gataaacgta tcgccagaac gcgttaaacg cgcatcaatc
    12961 ccatgattac gcaaaatgga acggacgttt ttagcaatcg ccagcaccac atgtttttct
    13021 ttcgaaccgt tgcgtccgat cgctccggta tcaattccgc cgtggcctgg atcgagaaca
    13081 acgacacgtt tgccgccaga ttttttggct ttcggcttgc tgtgtccgtt gctggttttt
    13141 aaaggttcgt ctttggcgat ggcttgcgac attcctgaca acgtcagggc agccaaaccg
    13201 gctttcagca cctggcggcg cgaagtgagt gtttttagtg gtttaaaagt gctcatacgg
    13261 cctgagttgt aataataaag ttccagatgt tatatcgtat cgcgtaatcc gttacgacgg
    13321 tttgatgttg agaattgttt tacttttcat ttcaatagtt gacaactccc cattatgcca
    13381 ctttttcaac cgattttcgt cagatattgg ctaattcgac cgttcacgcc ataatcagcc
    13441 ttttaacccg caaaaaggta acgaatacca tggagatacg cgtatttcgc caggaagatt
    13501 tcgaagaggt catcaccctt tgggagcgtt gcgacttgct gcgtccgtgg aacgatccgg
    13561 aaatggacat cgagcgtaag atgaaccatg acgtcagttt gtttttggtc gctgaggtaa
    13621 acggtgaagt ggtcggaacg gtgatgggcg gttatgacgg gcatcgcggg tctgcttatt
    13681 atcttggcgt gcatccagag tttcgtgggc gtgggattgc caatgcgttg cttaatcggc
    13741 tggagaaaaa gctgattgct cgtggctgcc cgaaaattca gatcaatgtg ccggaagata
    13801 acgacatggt gctcggaatg tatgaacgcc tgggatatga acacgccgac gtgctgagtc
    13861 tgggtaagcg tttgattgaa gatgaagagt actgagttcc atcctgtcca ttatgatgcg
    13921 cacggacgcc tgcgtttacc cttgctcttc tggcttgtgc tattgcttca ggcgcgaacc
    13981 tgggtgctgt ttgtcattgc cggtgcgtcg cgtgagcagg gtactgcgct gctaaatctg
    14041 ttttatcccg atcacgataa tttctggctg gggctgattc ctggcattcc ggcggtgctg
    14101 gcgtttttgt tgagcggtcg gcgggctaca tttcctcgca cttggcatgt gctctatttt
    14161 ctgttgctgt tggcgcaggt ggttttactt tgctggcaac cgtggctgtg gctgaacggt
    14221 gaatccgtta gcggtatcgg tctggcgctg gtagtggcgg atattgtggc gttaatctgg
    14281 ctgctgacca atcgacgttt acgcgcttgt tttaatgaag taaaagaata acggcacttt
    14341 ttggtgaatt tgcactccaa gcaacgttat tgaataacca aaggaagtga catgaaatcg
    14401 ctgcgtttaa tgttatgcgc tatgccattg atgctgaccg gctgttccac gatgtcgtca
    14461 gttaactggt ctgccgctaa cccgtggaac tggtttgggt cgtccaccaa agtgagcgag
    14521 cagggcgttg gtgaattaac ggcgtccaca ccactgcaag aacaagccat tgccgatgcg
    14581 cttgatggcg attatcgcct gcgcagcgga atgaaaaccg cgaacggcaa cgtggtgcgc
    14641 ttttttgaag tgatgaaggg cgacaacgtg gcgatggtga ttaacggcga tcaaggcacg
    14701 atcagtcgca ttgacgtgct ggatagcgat attcctgctg acaccggtgt taaaatcggt
    14761 acaccgttta gcgaccttta cagcaaagca tttggcaatt gccaaaaagc tgatggtgat
    14821 gataatcgtg ccgtcgaatg taaagccgaa ggcagtcaac atattagcta ccagttcagc
    14881 ggggaatgga gtggtcctga agggttaatg ccttcggacg ataccctgaa aaactggaaa
    14941 gtcagtaaaa ttatctggcg gcgttaattt gcgtctgaac aaaccgccgc cgcgaaaaaa
    15001 cacgtaaaat agcgctcaac aatgccacgg attgcgtggc attattattt tcaggaggaa
    15061 caatgtctca ggttcagagt ggcattttgc cagaacattg ccgcgcggcg atttggatcg
    15121 aagccaacgt gaaaggggaa gttgacgccc tgcgtgcggc cagtaaaaca tttgccgaca
    15181 aactggcaac ttttgaagcg aaattcccgg acgcgcatct tggtgcggtg gttgcctttg
    15241 gtaacaacac ctggcgcgct ctgagcggcg gcgttggggc agaagagctg aaagattttc
    15301 cgggctacgg taaaggcctt gcgccgacca cccagttcga tgtgttgatc cacattcttt
    15361 ctctgcgtca cgacgtaaac ttctctgtcg cccaggcggc gatggaagcc tttggtgact
    15421 gcattgaagt gaaagaagag atccacggct tccgttgggt tgaagagcgt gacctgagcg
    15481 gctttgttga cggtacggaa aacccggcgg gtgaagagac gcgtcgcgaa gtggcggtta
    15541 tcaaagacgg cgtggatgcg ggcggcagct atgtgtttgt ccagcgttgg gaacacaacc
    15601 tgaagcagct caaccggatg agcgttcacg atcaggagat gatgatcggg cgcaccaaag
    15661 aggccaacga agagattgac ggcgacgaac gtccggaaac ctctcacctg acccgcgttg
    15721 atctgaaaga agatggcaaa ggactgaaga ttgttcgcca gagcctgccg tacggcaccg
    15781 ccagtggcac tcacggtctg tacttctgcg cctactgcgc gcgtctgcat aacattgagc
    15841 agcaactgct gagcatgttt ggcgataccg atggcaagcg tgatgcgatg ttacgtttca
    15901 ccaaaccggt cactggcggc tattacttcg cgccgtcgct ggacaagttg atggcgctgt
    15961 aagcgtttct gattcgatga tgaaaggcca ggcagtaaca ttactgactg gcctttttat
    16021 tactgcttta acgccgcata tacctgatca accacccaac cataagttgc aattggcaac
    16081 tgaccgcttt cgaacatatt gggattcttt tgcggatcgg caaccggtga atgtggcttg
    16141 ttacttaaca tcacaatcgc catatgattc accggatcga taacggtcac cgttccggtc
    16201 cagccagtgt gaccgtaggt ttgcgggctt gccagcgtgc caaacgtcgg cgtcatggtg
    16261 gcattaccat ttacgcgcca gccgaggcca aaagtggcat cttccttaga gctggtggtg
    16321 aacatcttca ccgtttccgc actgaacagc tgcacatcgc catagccccc gccgttcagc
    16381 atcgtttgca ttaacaccgc aatatcgccg gtattggaaa acaaacctgc gtgcccggaa
    16441 acgccgccca tcgaataaaa ggctttttca tcgtgcacct gaccccagag agtggaggtg
    16501 cggatattcg ggaaatggat cacgccatcg cgggtattgc cgttcaattc cgtggcggca
    16561 atttgttgcg gtttaaagcc tttcagcagc gggttaaata ccgtatgtgt caggccgagc
    16621 gggcgataaa tcgactcttc aacatagcgg tcaagcggct gaccggtgac cgactcgacg
    16681 ataaatccaa gcagcatata atcgacatca ctgtaaatat gcttgctgcc gggctgatac
    16741 tctagcggcg tgcgcttgat catctccagc gtctggcctt tatcctggga atataacgcg
    16801 cccgcgaccg ctttattcgg gtattgcgga tctgccggga aaccgccgct gtgatgcagc
    16861 aggtcagaaa tccgcagggt gtttttgcct ttaatggtgt catttggact atcggcaaac
    16921 cccggaatat atttcgcaat ccgatcgtca ggatgcagtt tgccttcgct catcagcttt
    16981 tgcagggcga agttcgtggc gtacattttg gtgtttgagg ccaggtcata cagcgtcccg
    17041 gtggtggctt tgacaggctg ttccatcaac acgctgccat cgtacttttt cgccgctccc
    17101 caggctttgc gatacacaat ctgattatct ttaatgatca gcaggtttac gccgggataa
    17161 ccggcgtcca cttgctggct aatccagcga tccatctggt taagccgttc gacgttgaac
    17221 cctgctttct ctggcgaact ttctgtcaga acagggtatt ttgcggcgct gacgctacaa
    17281 ctaacagcca gcagagaaag atagagcatt gtccgtttca tgatatcagt ccagattgac
    17341 gttacggcag ccaaagagcg tggtgaaaat aaacccgcaa acccatgcca ccagaatccc
    17401 gccagcataa accgccattg ccggaaggat gccttgtgcg gaagtcatca gcggcagcgc
    17461 caccagacca gacggcccaa aggcgctgtt taagcccatc ggcagacccc accaggctat
    17521 caggccgata aacaaaccgc ccgctgcgcc gcctaaacag gcggtaataa acggtttcat
    17581 gcggggcagg gtgacgccgt aaatcaacgg ttcaccaacg cccagcagac cgggaataat
    17641 cgccccgcgt acctgactgc gtaatgcact gtgcggttgc gcccgccagt agagtgccag
    17701 cgccgcgccc acctggcccg cgcctgccat tgaaaggatg ggaaataagc tgttgaatcc
    17761 ctggctgtcc attaacgcga ggtaaacagg aataaagccc tgatgcacgc caaataccac
    17821 ggcgatcagg aacagcccgg ctaaaaccgc acaaccgaac ggattactgt tcaggtgcat
    17881 aaacagccat gacatacctt cgaataacca gccacccagc ggcataatga tcaggtacgc
    17941 aagcgtagcg gtgatcagca gggtgattaa cgaggtcagc agcatgtcga gatcgtccgg
    18001 cataaagcgg cgcaccatgc cttcaatgcg ggcgcaggcc cacgcggcaa tcagcacgcc
    18061 gataatattg ccgcgcggat cgatgggcag accaaagaaa tcgtgaaaac cggcgtagta
    18121 accggtggtt gcagcggggt tataaccgag caaaaagagt gcggcaataa ttgcgccatt
    18181 gacgcccgtg ccgccaaatg cctgggcggc gttatagccc accagaatca ccaggaaagt
    18241 gaacaaacct ttgctgaaca ccttcataaa attcagcgcg tcgggtagcg tgccctgagc
    18301 atctgccgga acgtgcatca ccgtggcaat taacgtcgct atccccagca gcagaccggc
    18361 ggcaataaaa ccggggatca gcggcgtgaa gatggtggcg aatttggcga gaaattgttg
    18421 cacgccggag gtttgtttgg cttttaactg acgtttgttc tgggcggcga tttctgcggc
    18481 atcctgtacc ggtgcctcgc ccagcagctc gctcatcgct tttgcggcac gatgcgcttt
    18541 accaggccca aaaacgacct gcacctggtc gctggtcaaa atgacgccct tcacgccttc
    18601 cagcgttttg atattgggat caaccagtga actgtcatgt acacccagac gcaggcgcgt
    18661 catacagtta ccacaactgg cgatatttcc cggtccgccg acacgggtaa gaatggtgtt
    18721 cagaagttca ctgctgatct ctttggccat gggttattcc ttgtctaaaa cctgacgaat
    18781 aaagccgccg tgttgatcca ggcgtttttt agcttctgcg gcatcgagat ttttcagcac
    18841 catcacaatg gccgttttac agttgcgctc gcaggcaatt aacgccgctt ccgcttgttc
    18901 ggcattacat ccggtggcgt ttttaacgat attgacctgg cgcacatgca gtttttcgtt
    18961 ggtggcgacc acatcgacca tcaggttgcc gaacactttg ccggatttaa tcatcagccc
    19021 ggtggagagc atattgagca ccagtttctg cgctgtacct gctttcatcc gcgaagaacc
    19081 ggtaaccact tcggcaccta caatcggtgt aatggcaaac tctgcggtgg ttgaaacggc
    19141 gctccccgga ttacaggaaa ttcccactgt gcggcagccg agctggcgtg cgtattccag
    19201 tccggcaatt acatacggcg tgcgaccact ggccgcaatg ccaaccacca catcctgcgc
    19261 ggttaagccg atgtttttca gatcgttaac accaccttcc cggctatctt cagcgccttc
    19321 caccgcatgc tgaatggcat attcgcctcc agcaatcaaa ccaaccacca aacccggttt
    19381 cacgccgtag gtgggcggac attcgctggc atccagaatc cccagacgac cggatgttcc
    19441 cgcaccgaga taaatcagac gaccgccgcc gcttacctgg gcgtggataa catcgatcgc
    19501 cgcggcgata tccggcagta cgcgctcaac ggcaagcggt acggttttat cttcatcgtt
    19561 gataatccgg cacatttcca gcgttgatac gcggtcaatt tcagccgagg cggcgttcga
    19621 gccttcggta atcatctttt caagttgcat cggtggtgac cttactattt acgatcaaat
    19681 aattgcagat gtatggaatc atatatcccg aattgacaga cttaaaggaa tcattgagtc
    19741 tacactcgca gagtgtgaag agcgtcataa gaacttaagc ggaatttttg ctgccagccc
    19801 aggagagtgg aagatgttgt acctgacgaa aatacgcaat gcggaaagtg aatttaccga
    19861 gaacgagcaa aaaattgctg actttctgcg ggccaacgtg agtgagctga aatccgtctc
    19921 ttcgcgcaag atggcgaaac agctcggcat cagccagtcg agtattgtga agtttgccca
    19981 gaagctcggc gcgcaaggat ttactgaatt gcgtatggcg ttaattggcg aatacagtgc
    20041 cagccgggag aaaacgaatg ccacggcgct gcacctgcac agttcgatta ccagtgatga
    20101 ttcgctggaa gtgattgccc gcaaactgaa tcgcgaaaaa gagctggcgc tggagcaaac
    20161 ctgcgcgttg ttcgactacg cgcggctgca aaaaatcatt gatgtcatca gtaaagcgca
    20221 atttattcag ataacgggcc tgggcggatc ggcgctggtg gggcgcgatc tgtcgttcaa
    20281 actgatgaaa attggctatc gcgtggcctg cgaagccgac acgcacgtac aagccaccgt
    20341 ttcccaggcg ttgaaaaaag gcgatgtaca aatcgctatc tcttacagcg gcagtaaaaa
    20401 agagattgtc ttgtgcgcag aagcggcacg aaagcagggg gcaacggtga ttgccattac
    20461 ttctctggct gactctccgc tgcggcggct ggcgcatttc acgctcgata ccgtttccgg
    20521 tgaaaccgaa tggcgtagct cgtcgatgtc tacccgcacg gcgcaaaatt ctgttaccga
    20581 tttactgttt gttggtcttg tgcaactcaa tgatgtcgag tcattgaaaa tgattcagcg
    20641 cagcagtgag ctaacacaac gcctgaaatg atgcataaag cagcgactgg attgagattt
    20701 tcctgaatta gtgagctgat ccgcagcaat attttgttta tcctgtattt tcagagggaa
    20761 tggagtgtaa cgctctgtat taacaaggag agcattaaaa tgggtaaact cacgggcaag
    20821 acagcactga ttacgggcgc attgcaggga attggcgaag gaattgccag aacttttgcg
    20881 cgtcatggcg caaacctaat cttgctggat atctcccctg agatcgaaaa gctggcggac
    20941 gaactgtgtg gtcgtggtca tcgctgtacg gcggttgtcg ccgatgtgcg tgacccggcg
    21001 tcggtagccg cagctatcaa acgcgcgaag gaaaaagaag ggcgcattga tatcctggtg
    21061 aataacgcag gcgtttgtcg tctgggcagt ttcctcgata tgagcgatga agatcgcgat
    21121 ttccatattg acatcaatat taaaggcgta tggaacgtca cgaaggcggt gctgccagag
    21181 atgattgcgc gcaaagatgg tcgcattgtg atgatgtctt cagtcactgg tgatatggtg
    21241 gccgatcctg gcgaaacggc gtacgcctta acgaaagcgg cgattgttgg cctgacaaaa
    21301 tcgctggcgg tggagtacgc gcagtctggt attcgcgtta acgccatttg cccgggatac
    21361 gtgcgcacac caatggcgga aagcattgcc cgccagtcga acccggaaga tccagagtcg
    21421 gtgctgactg aaatggcgaa agcaatcccg atgcgtcgcc tcgccgatcc gctggaagtc
    21481 ggcgaactgg cggccttcct cgcatcggat gaatccagct atttaaccgg tacacagaat
    21541 gtgattgatg gcggcagcac actgccggag acggttagcg tcggtatctg attcacctct
    21601 gtttcctccc tgcatttgtg gggaggattt cgttttaaac ccggttctta ttcccttttc
    21661 aacttccaaa tcaccaaacg gtatataaaa ccgttactcc tttcacgtcc gttataaata
    21721 tgatggctat tagaaagtca ttaaatttat aagggtgcgc aatggccgtt aacttactga
    21781 aaaagaactc actcgcgctg gtcgcttctc tgctgctggc gggccatgta caggcaacgg
    21841 aactgctgaa cagttcttat gacgtctccc gcgagctgtt tgccgccctg aatccgccgt
    21901 ttgagcaaca atgggcaaaa gataacggcg gcgacaaact gacgataaaa caatctcatg
    21961 ccgggtcatc aaaacaggcg ctggcgattt tacagggctt aaaagccgac gttgtcactt
    22021 ataaccaggt gaccgacgta caaatcctgc acgataaagg caagctgatc ccggccgact
    22081 ggcagtcgcg cctgccgaat aatagctcgc cgttctactc caccatgggc ttcctggtgc
    22141 gtaagggtaa cccgaagaat atccacgatt ggaacgacct ggtgcgctcc gacgtgaagc
    22201 tgattttccc gaacccgaaa acgtcgggta acgcgcgtta tacctatctg gcggcatggg
    22261 gcgcagcgga taaagctgac ggtggtgaca aaggcaaaac cgaacagttt atgacccagt
    22321 tcctgaaaaa cgttgaagtg ttcgataccg gcggtcgtgg cgcaaccacc acttttgccg
    22381 agcgtggcct gggcgatgtg ctgattagct ttgaatcgga agtgaacaac atccgtaaac
    22441 agtatgaagc acagggcttt gaagtggtga tcccgaaaac caatattctg gcggaattcc
    22501 cggtggcgtg ggtcgataaa aatgtgcagg ccaacggtac ggaaaaagcc gcaaaagcct
    22561 acctgaactg gctctacagc ccacaggcgc agaccatcat caccgactat tactatcgtg
    22621 tgaataaccc ggaagtcatg gacaaactga aaaacaaatt cccgcagacc gagctgttcc
    22681 gcgtggaaga caaatttggc tcctggccgg aagtgatgaa aacccacttc accagcggcg
    22741 gcgagttaga caagctgtta gcggcggggc gtaattaatg tttgcagttt catcaagacg
    22801 cgtgctgccg ggctttacct taagcctcgg caccagtctg ctgtttgtgt gcctgatttt
    22861 gctgctgccg ctctccgcgc tggtgatgca gctggctcag atgagctggg cgcagtactg
    22921 ggaggtgatc accaacccgc aggtagtagc ggcctacaaa gtaacgctgc tgtcagcgtt
    22981 tgtggcatcg atttttaacg gcgtttttgg cctgctgatg gcgtggatct taacccgcta
    23041 tcgctttccg ggccgcacgc tgcttgatgc gctgatggat ttaccctttg cgctgccaac
    23101 ggcagtcgcc ggtttaacgc tagcctcgct cttttctgta aacggttttt acggtgaatg
    23161 gctggcgaag tttgatatca aagtcaccta taccttgctg gggattgcgg tggcgatggc
    23221 ctttaccagc attccgtttg tggtacgtac cgtgcagccg gtgctggaag agttaggccc
    23281 ggaatatgaa gaagcggcgg aaacgcttgg tgcaacgcgc tggcagagtt tctgcaaagt
    23341 ggtgctgccg gagctttctc cggcgctggt ggcgggcgtg gcgctgtcgt ttacccgtag
    23401 tcttggtgaa tttggcgcgg tgatttttat cgccggaaat atcgcgtgga agacggaagt
    23461 gacgtcgctg atgatttttg tgcgcttaca ggagtttgat tacccggcag cgagcgcgat
    23521 tgcttcggtg atcctcgcgg catctctgct gctgctgttc tcaattaaca ctctgcaaag
    23581 tcgctttggt cggcgtgtgg taggtcatta atggcggaag ttacccaatt gaagcgttat
    23641 gacgcgcgcc cgattaactg gggcaaatgg tttctgattg gcatcgggat gctggtttcg
    23701 gcgttcatcc tgctggtgcc gatgatttac atcttcgtgc aggcattcag caaggggctg
    23761 atgccggttt tacagaatct ggccgatccg gacatgctgc acgccatctg gctgacggtg
    23821 atgatcgcgc tgattgccgt accggtaaac ctggtgttcg gcattctgct ggcctggctg
    23881 gtgacgcgct ttaacttccc tggacgccag ttactgctga cgctactgga cattccgttt
    23941 gccgtatcgc cggtggttgc cggtctggtg tatctgctgt tctacggctc taacggcccg
    24001 ctgggcggct ggctggatga acataatctg caaattatgt tctcctggcc cggaatggtg
    24061 ctggtcacca tctttgtgac gtgtccgttt gtggtgcgcg agctggtgcc ggtgatgtta
    24121 agccagggca gccaggagga tgaagcggcg attttgcttg gcgcgtctgg ctggcagatg
    24181 ttccgtcgcg tcacattgcc gaatattcgc tgggcgctgc tttatggcgt ggtactgacc
    24241 aacgcccgcg cgattggcga gtttggcgca gtgtcggtgg tttccggctc gattcgcggc
    24301 gaaacacttt cgctgccgtt acagattgaa ttgctggagc aggactacaa caccgtcggc
    24361 tcctttaccg ctgcggcact gttaacgctg atggcgatta tcaccctgtt tttaaaaagt
    24421 atgttgcagt ggcgcctgga gaatcaggaa aaacgcgcac agcaggagga acatcatgag
    24481 cattgagatt gccaatatta agaagtcgtt tggtcgcacc caggtgctga acgatatctc
    24541 actggatatt ccttcaggtc agatggtcgc gttgctgggg ccgtccggtt ccgggaaaac
    24601 cacgctgctg cgcattatcg ccgggctgga gcatcaaacc agcgggcata ttcgcttcca
    24661 cggcaccgac gtcagccgcc tgcacgcgcg cgatcgcaag gtcggtttcg tgttccagca
    24721 ttacgcgctg ttccgccata tgacggtatt cgacaatatc gcttttggcc tgacggtgct
    24781 gccgcgtcgc gagcgcccga atgccgcagc catcaaagcg aaagtgacaa aattgctgga
    24841 aatggtccag cttgcgcatc tggcggatcg ttatccggcg cagctttccg gcggccagaa
    24901 acagcgtgtg gcgctggcgc gcgcgctggc tgtagaaccg caaattctgc tgcttgatga
    24961 accgtttggc gcgctggatg cgcaggtgcg taaagagctg cgtcgctggc tgcgtcaact
    25021 gcatgaagag ctgaaattca ccagcgtgtt tgtgacccac gaccaggaag aggcgaccga
    25081 agtagccgat cgtgtagtgg tgatgagtca ggggaatatt gaacaggctg atgcgccgaa
    25141 tcaggtatgg cgcgaaccag cgacccgttt tgtactcgaa tttatgggcg aagtgaaccg
    25201 cctgcaggga accattcgcg gcgggcagtt ccatgttggc gcacatcgct ggccgctggg
    25261 ctacacacct gcttatcagg ggccggtgga tctcttcctg cgcccgtggg aagtggatat
    25321 cagccgccgt accagtctcg attcgccgct gccggtacag gtactggaag ccagcccgaa
    25381 aggtcactac acccaattag tggtgcagcc gctggggtgg tacaacgaac cgctgacggt
    25441 cgtgatgcat ggcgacgatg ccccgcagcg tggcgagcgt ttattcgttg gtctgcaaca
    25501 tgcgcggctg tataacggcg acgagcgtat cgaaacccgc gatgaggaac ttgctctcgc
    25561 acaaagcgcc tgataggttg agtgaatgtt aaacgcccgg aggcgcttcc cgcgatccgg
    25621 gctttttaat ggcaaggttt gtaacctgta gacctgataa gacgcgcaag cgtcgcatca
    25681 ggcaacacca cgtatggata gagatcgtga gtacattaga acaaacaata ggcaatacgc
    25741 ctctggtgaa gttgcagcga atggggccgg ataacggcag tgaagtgtgg ttaaaactgg
    25801 aaggcaataa cccggcaggt tcggtgaaag atcgtgcggc actttcgatg atcgtcgagg
    25861 cggaaaagcg cggggaaatt aaaccgggtg atgtcttaat cgaagccacc agtggtaaca
    25921 ccggcattgc gctggcaatg attgccgcgc tgaaaggcta tcgcatgaaa ttgctgatgc
    25981 ccgacaacat gagccaggaa cgccgtgcgg cgatgcgtgc ttatggtgcg gaactgattc
    26041 ttgtcaccaa agagcagggc atggaaggtg cgcgcgatct ggcgctggag atggcgaatc
    26101 gtggcgaagg aaagctgctc gatcagttta ataatcccga taacccttac gcccattaca
    26161 ccactaccgg gccggaaatc tggcagcaaa ccggcgggcg cattacccat tttgtctcca
    26221 gcatgggaac aaccggcact atcaccggcg tttcacgctt tatgcgcgaa caatccaaac
    26281 cagtaacgat tgttggcctg cagccggaag aaggcagcag tattcccggc attcgccgct
    26341 ggcctgcgga atatctgccg gggattttca acgcttctct ggtggatgag gtgctggata
    26401 ttcatcagcg cgatgcagaa aacaccatgc gcgaactggc agtgcgggaa ggaatattct
    26461 gtggcgtcag ctccggcggc gcggttgccg gagcactgcg ggtggcaaaa gctaaccctg
    26521 gtgcggtggt ggtagcgatc atctgcgatc gtggcgatcg ctacctttcc accggggtgt
    26581 ttggggaaga gcattttagc cagggggcgg ggatttaaga ttattgcgca ggcaccgttt
    26641 tatccgtctg cgcaattagc gcatgtaaaa aaggctgtgc gttctcatcg ctcttaccgg
    26701 ggatcttcac aatatacggc ttcccggtaa tcgatgacga cgaagcaacc ttatcaataa
    26761 actgctcggc agtgtcaatg cggttacggg tattgcccag cttcagacgc agatgagaaa
    26821 ccgcttcatc gcaggtatgt tcatcaccgt tgcgcacaaa tatcaaatcc tttttctgtg
    26881 ctaatccctc cagcatggcg ttgatgcggg cttcttcatg ggcagttaac ttcgcgtaag
    26941 cggggagtgt cattagtagt gtaatgacca gacaaatgat tttcttcatt gaattacctt
    27001 atccttgttt tgtgatagcc gatttgactg ccagaatcag gtaaagtttc ggttggaata
    27061 cgatgaggat catcggcaag gagaaaaaat taaatgagta gtttgttgtt gtttaacgat
    27121 aagagcaggg cgctgcaggc ggatatcgtc gccgtgcagt cgcaggtggt ttacggcagc
    27181 gtgggcaaca gcattgccgt gcctgctatc aaacagaacg gtctgaatgt ctttgccgtg
    27241 ccgacggtat tgctgagcaa tacgccgcat tatgacactt tctacggtgg tgcgattccg
    27301 gacgaatggt ttagcggcta tttgcgtgcg cttcaggagc gtgatgcgct gcgccaactt
    27361 cgtgctgtaa ccacgggcta tatgggaacg gcatcgcaaa tcaaaatcct tgccgagtgg
    27421 ctgactgcgc tacgcaaaga ccatcctgac ctattgatca tggtcgatcc ggtgattggc
    27481 gatattgata gcggaattta tgtcaaacct gaccttcccg aggcgtatcg acaatattta
    27541 ctgccgctgg cgcagggaat tacccccaat atctttgagc tggaaatcct gaccggtaaa
    27601 aattgccgcg atctcgacag tgccattgct gccgcaaaaa gtctgctttc agacacatta
    27661 aaatgggtgg tgattaccag cgcctccggt aatgaagaaa atcaggagat gcaggtggtg
    27721 gtggtcagtg ccgacagcgt gaatgtcatt tcccattcac gggtaaaaac cgacctgaaa
    27781 gggactggcg acctgttttg tgctcagctt atcagtggtt tgctgaaagg gaaggcgtta
    27841 aacgatgcgg tgcaccgtgc ggggttgcgc gtactggaag tgatgcgcta cacccagcag
    27901 catgagagcg atgaattgat tttgccgccg ctggcggaag cataaaaaat ggcgccgatg
    27961 ggcgccattt ttcactgcgg caagaattac ttcttgatgc ggataaccgg ggtttcaccc
    28021 acggttacgc taccggacag tttgatcagt tctttgattt cgtccatgtt ggagataaca
    28081 accggagtca gggtagactt ggctttctct tccagcagcg gcagatcaaa ttcaatgaca
    28141 gtatcgccaa ctttcacgcg ctgaccttct tcagcaatac gcttgaagcc ttcgcctttc
    28201 agttcaacgg tgtcgatacc gaagtggacg aacagttcaa cgccgctatc agattcgata
    28261 gagaacgcgt ggttggtttc aaagatttta ccaatggtgc cgtctacagg cgcgaccatt
    28321 ttgttacccg ttggtttgat agcaatacca tcaccaacga ttttttccgc aaaaacgaca
    28381 tccggcacgt cttcgatatt gacgatctcg ccagagagcg gagcaatgat ctcaatagtt
    28441 ccggtatcct tcttgtcgtc ggaaaccaga gatttcagtt tatcgaacaa acccatgatc
    28501 ttctcctaag cagtaaattg ggccgcatct cgtggattag cagattgttt tttcttcaat
    28561 gaacttgtta accagcgtca ttaactcgtc cgttgtcggt tgagcaagag cctgctctgc
    28621 taacaccttc gcatcttcga agttcgtgtt acggataatc ttcttaatgc gcgggataga
    28681 aatggcgctc atagagaatt cgtccagacc catccccagc aacagaagtg tagcacgttc
    28741 atcgccagca agctcaccac acatgccagt ccatttgcct tcagcatgag aagcatcaat
    28801 aacttgcttg atcaagttca gcacggacgg tgacattggt tggtaaaggt gtgaaatcat
    28861 atcattacca cggtcaactg ccagagtgta ctgcgttaaa tcattggtgc cgatactaaa
    28921 gaaatcaact tctttggcta aatgacgtgc aattgttgcg gcagccggtg tttccaccat
    28981 tacgccgatt tcaattgact cgtcaaacgc tttaccttcg tcgcgcagtt cctgtttgta
    29041 gatttcgatc tctttgcgca gtgcacgcac ttcttcaaca gagatgatca tcgggaacat
    29101 aatgcgcaat ttaccgaaag ccgaggcacg caggatagcg cggagctgat cgcgcaggat
    29161 ctctttacga tccatcgcga tacggatagc gcgccagccg aggaacgggt tctcttcttt
    29221 cgggaagttc atgtatggca gctctttgtc gccgccgatg tccatggtac gaacgataac
    29281 cgcctgcgag ccacacgctt cagccactgc tttgtaagca gcaaactgtt cttcttcagt
    29341 gggcagcgcg tcgcggtcca tgaacaggaa ctcagtacga tacagaccaa cgccttcagc
    29401 gccgttacgc tctgcacctt caacgtcacg aaccgtacca atgttagcgc acacttctac
    29461 ctggtgaccg tccagcgtaa tagctggcag atctttcagt ttagcaagct ctgctttttc
    29521 agaagccact tgctcctgaa cagcgcgcat tttatcaata acttcgttgg ttggattgac
    29581 gtaaacctga ttatttacgg catccagaat cagatagtcg tcatttttca cctgagaggt
    29641 gacgctaccg gtacccacga tagcaggcag ttccagagaa cgcgccatga tagaggtgtg
    29701 ggaagtacgg ccacccgcgt cggtgatgaa acccagcacc ttcttcaggt tcagctgtgc
    29761 ggtttcggac ggcgtcaggt cagcggcaac cagaatgact tcatcctgaa tggcgctcag
    29821 gtcgataatc ttcaggccca ggatgttgcg cagcaggcgc ttaccgatat cacgtacgtc
    29881 agccgcacgt tctttcaggt attcatcatc cagctcttcc agggcagaag cctgaccttc
    29941 gataacttca tgagcagctg cgtcagctgt catgtgctta tctttaatca gggctatgat
    30001 ttcctgctcc agctcctcat cttcgagcag cataatatgc ccttcaaaga tggcttcttt
    30061 ttcttcaccg aacgtttcac cagctttcgt tttgatcgtt tccagctggg ctgatgcctt
    30121 ggcacgaccg ctcagaaaac gttcaacttc ctgatcaacc tggtcggcag aaattttttt
    30181 ccggtcaatg acaatttcgt cttctttcag aagcagagct ttaccgaaag cgatacccgg
    30241 ggatgctaaa atgcctgaaa tcataaccct accttacttg tgactgattt ttaaaagaac
    30301 ccgggaaatt actcgagttc cgccatcagt ttaaccagat gttcaaccgc tttctgctcg
    30361 tcttcgcctt ctgcggagat agtcacaacg gtaccttgag tcaggcccag agtctgcagt
    30421 ttaaacaggc ttttcgcgct ggcgcttttg ccgttggaag tcacagtaat ttcagaagtg
    30481 aagcccttag cttcttttac aaactgggca gcagggcggg tgtgcagacc gttcggagcg
    30541 gtaatggtaa cttcttgctg gaacattgta tttccccaac ttataggttt agtgttgtgg
    30601 aactaaagtc tagcctggcg gttcgacttt agcctgtatt gttagcgcca gtttttaaca
    30661 gacgcgacgc acgaagagcg caatacagtc cattgctggc gggtgttgac cgctgacgtt
    30721 tcgtacgtca ttaaacatta tgccgctaaa ggaagaattg aaccaaatca taaaatcgat
    30781 tcagctttgg cttttcctgt aacgattaat ttcgcgcatc aaaataatta gtctggttaa
    30841 ataccagttc cgacaggctg aatcaatgcc aggaggggcg aaagtttgaa gcaggccaca
    30901 aaaaagcacc taaaaaggtg cttttttacg catttttaac aagctggcat tactgttgca
    30961 gttctttctc agtgaagaga tcggcaaaca atgcggtgct taaataacgc tcacccgatg
    31021 acggtagaat aaccacaata ttcttgttgg taaagctttc atcttcttgt agtttcaacg
    31081 ccgcagcaac agctgctcca gaagagatac ctgcaagaat accttcttct tccatcagac
    31141 gacgtgcggt agaaatcgct tcttcattgg tgatgccaat gactttatcg accagcttga
    31201 gatcgaggtt agctgggata aaaccagcgc caataccctg aattttatgc gggccaggtt
    31261 taatctcttc accagccagt gcctgggcga taactggaga atcggttggc tcaacggcga
    31321 cagagataag atcggtcttg cctttggtgc ctttaatgta gcggctgacg ccagtcagcg
    31381 taccgccagt cccaacgcca gcaataaata catcaacctg accgtcggta tcttcccaga
    31441 tctccggacc ggtggttttt tcgtgaattt cagggtttgc cggattgctg aattgttgca
    31501 gcagcaggta tttctctgga ttgctggcga caatttcttc tgctttttgg attgcgcctt
    31561 tcatgccttt agcaccttcc gtcagcacca ggtttgcacc taacgctttc agcagcttgc
    31621 ggcgttcaat actcatggtt tctggcatgg tcagggtgag tttgtaaccg cgagcggcag
    31681 ctacataggc cagtgcaatc ccggtattac cgctggtcgg ttcaaccagt tcaacgcctg
    31741 gtttcagcac gccgcgcttt tcggcatccc aaatcatgtt ggcaccgata cggcacttaa
    31801 cgctgaagct ggggttacga gattccacct tcgccagaat gcgtccgtta ccgatgcgat
    31861 tcaggcgaac cagcggcgtg tgaccgatag tcagcgagtt atcttcaaaa atcttactca
    31921 tggcctgtcc ttaactgtat gaaattggga tacaacaggt agcatacccg ctcagagaat
    31981 atgcggaagt aaggatttag catatctata tacagaaggg aaataatgac atgcaagatg
    32041 gaataagggg cggcataagc cacccctgtt tcacacaaac ggtttacaaa ataaccggta
    32101 gattgttacc gccacatcgc gtgtttatcg cgatagcaat cgacccacat cgccgtcgcg
    32161 ccacaaacgg caacgggcat gatgaacaga ttaagcagcg ggatcatcgt aaacaggctg
    32221 gttaaagcac caaactgcat attggtgatt ttgcgtgtgc gcagggcggt gcgcatctct
    32281 ttaaacggca ctttgtggtt atcgaagggg taatcgcaat actggatggc taacatccag
    32341 gcgctaaaca ggaaccacag taccggcgcg acggtttgcc caataccagg gattaagtaa
    32401 agaattagca atacaattgc gcgcggcaga taccaggcaa atttttgcca ttcgcgtttc
    32461 atgattcgcg gcacatcttt catgataccg aaaatcccgg tatctggcgg tgtagcgcca
    32521 gtcaatcgtg cttccagttg ttcagccaat aaaccgttaa acggagcggc aatccagtta
    32581 gcaatcgtgg agaagaaata gccaaacact aacagcacag agatgacagc cagaggccac
    32641 aacagataac tcagccattg tagccagtcc ggaacgtaac tcatgagagt cgggatccag
    32701 acatcgagct gtgtaaagag ccaccagaat gcgcccccca tcaacaaaat attgaccagc
    32761 agcggtaaaa taacgaaacg ccgaatccca ggttgcgaga cgagcttcca gccttgcgca
    32821 aaatagtaaa aaccgctgcg tggggcagat gtgaatgatg aaaccataat caggatgagc
    32881 tccttttgac caatcccagg aaaattctgc gtattttacc gggtaattgc gcaatggaca
    32941 gttaggatat gttcgaaaaa acagcaaaaa gcacgatttc atctatcttt gtgctgtgaa
    33001 agttaatagt gcacttgcac ttgaggtaat cggcaaatac tcttagtgag taaatgtttg
    33061 ccgtggtggc aaggtgttag aacaacagag aatataatga tgcaggattt gcgtctgata
    33121 ttaatcattg ttggcgcgat cgccataatc gctttactgg tacatggttt ctggaccagc
    33181 cgtaaagaac gatcttctat gttccgcgat cggccattaa aacgaatgaa gtcaaaacgt
    33241 gacgacgatt cttatgacga ggatgtcgaa gatgatgagg gcgttggtga ggttcgtgtt
    33301 caccgcgtga atcatgcccc ggctaacgct caggagcatg aggctgctcg tccgtcgccg
    33361 caacaccagt accaaccgcc ttatgcgtct gcgcagccgc gtcaaccggt ccagcagccg
    33421 cctgaagcgc aggtaccgcc gcaacatgct ccgcgtccag cgcagccggt gcagcagcct
    33481 gcctatcagc cgcagcctga acagccgttg cagcagccag tttcgccaca ggtcgcgcca
    33541 gcgccgcagc ctgtgcattc agcaccgcaa ccggcacaac aggctttcca gcctgcagaa
    33601 cccgtagcgg caccacagcc tgagcctgta gcggaaccgg ctccagttat ggataaaccg
    33661 aagcgcaaag aagcggtgat tatcatgaac gtcgcggcgc atcacggtag cgagctaaac
    33721 ggtgaactgc ttcttaacag cattcaacaa gcgggcttca tttttggcga tatgaatatt
    33781 taccatcgtc atcttagccc ggatggtagc ggcccggcgt tattcagcct ggcgaatatg
    33841 gtgaaaccgg gaacctttga tcctgaaatg aaggatttca ctactccggg tgtcaccatc
    33901 tttatgcagg taccgtctta cggtgacgag ctgcagaact tcaagctgat gctgcaatct
    33961 gcgcagcata ttgccgatga agtgggcggt gtcgtgcttg acgatcagcg ccgtatgatg
    34021 actccgcaga aattgcgcga gtaccaggac atcatccgcg aagtcaaaga cgccaacgcc
    34081 tgatacactt aaggcaaatt aactcctctt cgaacccccg cttgtcgggg gtttttagca
    34141 ttgatggtgc gatatggaat caatcgaaca acaactgaca gaactgcgaa cgacgcttcg
    34201 ccatcatgaa tatctttatc atgtgatgga tgcgccggaa attcccgacg ctgaatacga
    34261 caggctgatg cgcgaactgc gcgagctgga aaccaaacat ccagaactga ttacgcctga
    34321 ttcgcctacc caacgtgtag gcgctgcgcc gctggcggct ttcagccaga tacgccatga
    34381 agtaccaatg ctgtcactgg ataacgtttt tgatgaagaa agctttcttg ctttcaacaa
    34441 acgtgtgcag gaccgtctga aaaacaacga gaaagtcacc tggtgctgtg agctgaagct
    34501 ggatggcctt gccgtcagta ttctgtatga aaatggcgtt ttagtcagtg ccgcgacccg
    34561 tggcgatggc accaccgggg aagatatcac gtctaatgtg cgtactattc gcgctattcc
    34621 gctgaagctg cacggagaga atatcccggc gcgtctggaa gtgcgtggtg aagtgttcct
    34681 gccgcaggcg gggttcgaaa agattaacga agatgcgcga cgcacgggcg ggaaagtttt
    34741 tgctaaccca cgtaatgcgg cagctggttc actgcgtcag cttgatccgc gtattacagc
    34801 gaagcgaccg ctcacttttt tctgctatgg cgttggtgtt ctggaaggtg gcgagctgcc
    34861 ggatactcat cttggccgtt tactgcaatt taaaaagtgg gggttgccgg tcagcgatcg
    34921 ggtaacgctt tgtgaatcgg cggaagaagt gctggcgttc tatcacaaag tggaagaaga
    34981 ccgcccgacg ctgggctttg atatcgacgg cgtggtgatt aaggtcaact cactggaaca
    35041 gcaggagcag cttggctttg tcgcgcgtgc cccgcgctgg gcggtagcgt ttaaattccc
    35101 ggcgcaggag cagatgacct ttgtgcgtga cgtcgagttt caggttgggc gtactggcgc
    35161 gattacgcct gttgcgcgtc tggaacctgt ccatgttgct ggcgtgctgg tgagtaacgc
    35221 aaccttacac aatgcggatg aaatcgaacg tcttggttta cgcattggcg ataaagtggt
    35281 gattcgccgc gctggcgacg tgatcccgca ggtggttaac gtcgtgcttt ctgaacgccc
    35341 ggaagatacc cgtgaggttg tattcccgac gcattgtccg gtatgtggtt ctgacgttga
    35401 gcgtgtggaa ggtgaagcgg ttgcccgctg taccggtggc ctgatttgcg gagcgcagcg
    35461 taaagagtcg ctgaaacact ttgtttcccg ccgtgcgatg gatgttgacg gaatgggcga
    35521 caaaatcatc gatcagctgg ttgaaaaaga atatgtccat actccggcag atctgttcaa
    35581 actcaccgca ggcaaactga ccggactgga gcgtatgggg ccaaaatcgg cacaaaacgt
    35641 ggttaacgcg ctagaaaaag cgaaagaaac cacctttgct cgcttcctct atgcacttgg
    35701 catccgtgaa gtcggcgagg ccaccgcagc aggtctggcg gcatatttcg gcacgctgga
    35761 agcgctggaa gccgcttcga ttgaagagct gcaaaaggtg cctgatgttg gcattgtcgt
    35821 tgcatcccac gttcacaact tctttgccga agaaagcaac cgcaatgtca tcagcgagct
    35881 gttggcggaa ggtgttcact ggcctgcgcc gatcgttatc aacgcggaag agattgacag
    35941 cccgtttgct ggtaaaaccg tggtgcttac gggcagctta agtcagatgt cacgtgatga
    36001 cgctaaagct cgactggtcg aactgggcgc gaaagtcgcg ggcagcgtgt cgaagaaaac
    36061 cgatctggtg atagcgggtg aagctgcagg atctaaactg gcgaaggcgc aggaactggg
    36121 cattgaagtc atcgacgaag cggaaatgct gcgtttgctg ggtagctgag atggaaaaag
    36181 agcagctgat tgaaatagcc aatacgataa tgccgtttgg caaatacaaa gggcgtcgct
    36241 taatcgacct gccggaggag tatctgctgt ggtttgcccg caaagatgag ttcccggcag
    36301 ggaagctcgg tgagctaatg caaatcacgc tgctgattaa aaccgagggg ctgacgcaac
    36361 tggtccagcc cctgaagcgt ccgctttaag ctttatcggt gctgctttcc tgctgcgcct
    36421 gtaactgttc ggtctggcgt ttgtatcgac gcgccagcac cgcacagacc atcaattgga
    36481 tctgatggaa aatcatcagg ggcagcacca tcataccgat caccgatgtg gggaacagaa
    36541 tgtttgccat cgggatgcca tttgccagac tctttttcga accacaaaag acgatagtaa
    36601 tttcatctgc cttattgaag cccagtcggc gtgccataaa gacgttaact acaatcacga
    36661 tagccagaag aacgcagctg accaccacga taaacagcaa tgatccccag ccaactttat
    36721 gccagatacc attaacgacg gcttcgctga acgctgtata aaccaccaac agaatggacg
    36781 tctggtcagt tttcgcaatc cattttttat tgcgcgacac ccagtcacca atccacggcc
    36841 gggaaagatg ccccaacaca aacggcagca gcagttgcag cataatttta ccgacctgct
    36901 caaggctgcc ccctgcaccg tgaacattca tcaccagacc aaccagcaat ggtgaaagga
    36961 aaatccccag caggctggat gctgacgcag aacaaaccgc cgccgcgacg ttaccgcccg
    37021 ccattgacgt gaaggcgatt gcagactgca cggtagccgg gagaatgcac aagtagagaa
    37081 aaccggagta gagcatcggg tcgacattta ccggtttcca ccaggcaaac agtacaccca
    37141 gaatcggaaa cagcacgaag gtgctgcaaa ttacccacaa atgcagtcgc cagtgaccac
    37201 cgccagcaat aatcgcctca cgcgacaact tcgcgccgtg cataaagaac agcagggcaa
    37261 tcgctgcggt ggtcagattt tcaaagaagg ggacgaaatc gcctctggcc ggaaagaaag
    37321 aggccagcaa caccaccgtg atcagggtta aggtgaaagg atcgaggata cgaaaaagtt
    37381 tcataaagac tccagatgat cgatggttct attgtgcttc ttccagtttg agaaataaaa
    37441 ttgatttatt gcatccattc atgaagaaaa cagatgaatt attctttaaa acaattaaag
    37501 gttttcgtca cagtagcgca ggagaaaagt tttagtcgtg caggagagcg tatcggcctg
    37561 agccagtcgg cagtgagtca cagtgtgaag gaactggaaa atcatactgg tgttcgcctg
    37621 ctggacagaa ccacgcgtga agtggtgctt acagatgcag ggcagcagct ggctttgcgt
    37681 cttgagcgac tgctggatga actgaacagc acgttgcgcg ataccgggcg tatggggcaa
    37741 caactgagcg gaaaagttcg ggtcgctgcc agccagacca tttccgcgca tcttattccg
    37801 caatgcattg ctgaaagcca tcgccgctat ccagatattc agtttgtcct gcacgatcgt
    37861 ccgcagcagt gggtgatgga aagtattcgc cagggagatg tcgactttgg catcgtcatc
    37921 gatccaggcc cagtgggcga tctgcaatgt gaagcgattc tttccgagcc tttctttctg
    37981 ctttgccatc gcgatagcgc tttggccgtc gaagattatg taccctggca ggcattacag
    38041 ggagcgaaat tggtgttgca ggattacgcg tcaggcagcc gaccgctgat tgacgcagcg
    38101 ctggcgcgca atggtattca ggcgaatatt gtgcaggaga ttggacatcc ggcgacgctg
    38161 ttcccgatgg tagccgcagg catcggcatc agtattcttc ccgcactggc gctaccattg
    38221 cctgaaggta gcccactggt ggtaaagcgc attacgccgg ttgttgaacg ccagttgatg
    38281 ctggtgcgca ggaagaaccg ttcactttcc accgccgctg aagcgttatg ggacgtggta
    38341 cgagaccagg gcaatgcgct aatggctggt cgggaagggg atccgttgta tcagatatag
    38401 agtgaattca tactgccggg agccccggca gtaatcaatc agaagttaaa tttgatggag
    38461 tagattatcg catcctggta aaaatcttcg cccagtttgt catccgcata tcgatactga
    38521 atccccgtag taatgtgtga tgttgcattc caccacagtg caactgcgcc attcagccct
    38581 tctttaccgc cattacccgc tgcataggta gcgtcacggt caaactcgta ctcgttccag
    38641 ttggtaagag tgaatttctc gctgcccagc ataaagttgt aacctgcaac ccagccggcg
    38701 acatagccgt tgtcgccagt gtaataggtt tgatctgtat aacgcttagc aaagaacggt
    38761 ttgaaccacc aaccgctgcc ggtgaaattg tagccgatac cgtacaggaa catatcgtcg
    38821 tggaaattca cgcgattcgc agaaccgtag gtgccatacg catgcaagta gagattaaat
    38881 ccggtgtcac ccaggtaaat acggttggta tttttaaagg tataacgctg ctcgctacct
    38941 ggtttattat ggcgaccgtt atagaagttt tcccagtcga agaacccgta catttctccc
    39001 caactaaagt tagcgccacc ttcaaattca agataaccaa aatcatcttt gtgtgatttg
    39061 gtcgacgatt tttcggtagt ccggctggtc cagtccagat aatgcacgcc gatatctgca
    39121 aaaccgcctt taaattctgc atgagataca acaggtatcg ctaatataga ggaaagtgtc
    39181 agagttaaaa gatgtttttt catagcataa ttccctatgc cgatcgttat tagtagattg
    39241 cttaataaag tggtttgcta aaaacgacat attgttaatg caaaggaatt aatatcgcca
    39301 atacagtttt taccgtggat taatagagaa aagatataaa tccatcgata tcgaatcgct
    39361 attgaatgcg tgagaaaagt gtattggtaa gagccgggac aacctcgcta taaaaaggcg
    39421 ttagattcca ccctacagaa aaaggatatg tatgtctcag gttcaatttt ctcataaccc
    39481 gctgttttgc atagatatta tcaagactta taaacctgat ttcacgccac gagtggcctt
    39541 tattttaggt tccgggctcg gcgcgctggc cgatcagatt gagaacgctg tcgcaatttc
    39601 ctacgaaaag ctgccgggct tcccggtaag tacggtacat ggtcatgcgg gggagttagt
    39661 gctgggccat ctccagggcg taccggtggt atgtatgaaa ggtcgcggac atttctacga
    39721 aggtcgtgga atgaccatta tgactgacgc aattcgtacc tttaagctgc tgggctgcga
    39781 gctactgttc tgcaccaatg cggcaggctc gctgcgtccg gaagtggggg caggcagcct
    39841 ggtcgcattg aaagatcata tcaacaccat gcccggtacg ccgatggtgg gtcttaacga
    39901 tgatcgtttt ggagagcgct tcttctcact ggcaaatgcc tacgatgcgg aataccgcgc
    39961 actgttacaa aaagtggcga aagaagaggg tttccctctg acggagggcg tgttcgtctc
    40021 gtatccgggg ccgaatttcg agactgcggc ggaaattcgc atgatgcaaa ttattggtgg
    40081 ggatgttgtt ggtatgtctg tggtgcctga ggttatttca gctcgccatt gcgaccttaa
    40141 agtcgttgcg gtctctgcga ttaccaatat ggcggaaggt ttaagcgatg tgaaattgtc
    40201 acatgcgcaa acgctggcgg ctgcggagct ctctaagcag aacttcatca accttatttg
    40261 tggctttctg cgcaaaattg cctgagaaaa acaataagaa acggcctcgc gggtgaggcc
    40321 aaatgatgcg acaaggaaac gattatgagc atcgcgatgc gcttaaaggt aatgtccttt
    40381 ttgcaatatt ttatctgggg gagctggctg gttaccctcg gctcttacat gattaatacc
    40441 cttcatttca ccggcgctaa tgttggcatg gtttacagtt ccaaagggat cgccgcgatt
    40501 attatgcctg gtataatggg gatcatcgca gacaaatggc tgcgcgcaga acgtgcatac
    40561 atgctgtgtc acctggtgtg tgcgggcgta cttttttatg cggcatccgt aactgatccg
    40621 gatatgatgt tttgggtgat gttagtcaat gcgatggcgt ttatgccgac tattgcgtta
    40681 tcgaacagcg tctcttattc ctgtcttgcc caggcagggc ttgacccggt gaccgctttc
    40741 ccgcccattc gcgtttttgg tacggtgggg ttcattgtcg cgatgtgggc agtaagcctg
    40801 ctgcatctgg aattgagtag tctgcagctg tatatcgcgt ccggtgcgtc attgctgctg
    40861 tcggcttatg cgctgacttt gccgaagatt ccggttgcgg agaaaaaagc gaccacatcg
    40921 cttgccagca agctgggtct ggatgccttc gtgctgttta aaaatccacg catggccatc
    40981 tttttcctct ttgccatgat gctgggtgcg gtactgcaaa ttaccaacgt ttttggtaat
    41041 ccgttcctac atgatttcgc ccgtaacccg gagtttgctg acagttttgt ggtgaaatat
    41101 ccctccattt tactgtcagt ttcacagatg gcagaagtgg gctttatact gactatccca
    41161 ttctttttaa agcgatttgg cattaaaacc gtcatgctga tgagtatggt ggcctggacg
    41221 ctgcgctttg gcttcttcgc ctatggcgat ccgtcaacaa ccggatttat tttgctgctg
    41281 ctgtcgatga ttgtttatgg ctgtgcattc gatttcttca atatttctgg ttcggtattt
    41341 gtcgaacagg aagttgattc cagcattcgt gccagcgcgc aggggctctt tatgaccatg
    41401 gtaaatggtg tcggcgcatg ggttggctcg attctgagtg gcatggcagt agattacttt
    41461 tcggtggatg gcgtaaaaga ctggcaaact atctggctgg tgtttgcagg atatgctctt
    41521 tttctcgcag tgatattttt ctttgggttt aaatataatc atgaccctga aaagataaag
    41581 catcgagcgg tggctcatta aaaggattcg cagctctgct cttcagagct gcttttatga
    41641 taaaggttaa ttagtgaaag atattttatt ttcttccggc gttggttttg gcattggtgc
    41701 tttgtttaca atcgtgcgct tgcctattcc tgtaccaaat gtattaccag gtatattatc
    41761 cattgtgttt atgtatgtcg gatatctggt ggtgaaatac tttatgcaat gataatttaa
    41821 tacgatgtat ttattatatg gagcacttaa ttatggaacg cgtatacaga acagatctta
    41881 agttgctccg ttattttctt gccgtagcgg aagagttgca ttttggccgc gcagcagcgc
    41941 gtttaaatat gtctcagcct ccgctcagga ttcatattaa agagctggaa aatcaactcg
    42001 gcacgcagct ttttattcgc cattcgcgca gcgtcgtact gacacacgcg ggcaaaatct
    42061 tgatggaaga atcgcgtcga ttgctggtga atgctaataa tgtattggct cgggttgaac
    42121 aaataggtcg gggagaagca gggcggattg aactcggcgt agtgggaacg gctatgtggg
    42181 gacggatgcg cccggttatg cggcgattcc tcagggaaaa tcctaacgtt gaagttcttt
    42241 ttcgcgaaaa gatgcccgcg atgcaaatgg ccctgctgga acgacgtgaa ctcgatgccg
    42301 ggatctggcg aatggcgaca gaaccaccga caggttttac cagcttacgg ttgcatgaat
    42361 cggcgtttct ggtggcgatg cctgaagagc atcatctctc atcattttcc accgttccgc
    42421 tggaagcgct acgtgacgag tattttgtta caatgccgcc cgtgtacact gactgggatt
    42481 ttttgcagcg agtttgccag caggtgggat tttcaccggt tgttattcgc gaagttaatg
    42541 aaccgcaaac ggtactcgcc atggtcagta tgggtattgg tatcacattg atagcggaca
    42601 gctacgcaca aatgaactgg ccaggtgtca ttttccgtcc gctcaaacag cgcatccctg
    42661 cagatttata tattgtttat gaaacacagc aggtgacgcc cgcgatggtt aagctgttgg
    42721 ctgcattgac acagtaggtg aggagacagg aattgccgga aatagtcgtc tgctaagtga
    42781 agcgcatcag gcaatttcgc aaatcgcaga tagcaaaaaa gcgcctttag ggcgcttttt
    42841 tacattggtg ggtcgtgcag gattcgaacc tgcgaccaat tgattaaaag tcaactgctc
    42901 taccaactga gctaacgacc cgaagtggtg ggtgatgacg ggatcgaacc gccgaccccc
    42961 tccttgtaag ggaggtgctc tcccagctga gctaatcacc cac
//
LOCUS       DAZUDJ010000040        41966 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.040, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000040 DAZUDJ010000000
VERSION     DAZUDJ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41966
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.040"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(325..401)
                     /locus_tag="ACHY1N_002861"
     tRNA            complement(325..401)
                     /locus_tag="ACHY1N_002861"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(365..367),aa:Met,seq:cat)
     gene            610..1707
                     /gene="mltA"
                     /locus_tag="ACHY1N_002862"
     CDS             610..1707
                     /gene="mltA"
                     /locus_tag="ACHY1N_002862"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HFS4045148.1"
                     /translation="MKGRWVKYLLMGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGI
                     DAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGA
                     LSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDR
                     GEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG"
     gene            1784..2590
                     /gene="tcdA"
                     /locus_tag="ACHY1N_002863"
     CDS             1784..2590
                     /gene="tcdA"
                     /locus_tag="ACHY1N_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HFS4045149.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSW
                     AAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
                     PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGT
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKMMAKAARQG"
     gene            complement(2641..3084)
                     /gene="csdE"
                     /locus_tag="ACHY1N_002864"
     CDS             complement(2641..3084)
                     /gene="csdE"
                     /locus_tag="ACHY1N_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HFS4045150.1"
                     /translation="MTNPQFAGHPFGTTVTAETLRNTFAPLSQWEDKYRQLIMLGKQL
                     PALPDELKAQAKEIAGCENRVWLGYTVTENGKMHFFGDSEGRIVRGLLAVLLTAVEGK
                     TVAELQAQSPLALFDELGLRAQLSASRSQGLNALSEAIIAAAKQV"
     gene            complement(3084..4289)
                     /gene="csdA"
                     /locus_tag="ACHY1N_002865"
     CDS             complement(3084..4289)
                     /gene="csdA"
                     /locus_tag="ACHY1N_002865"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HFS4045151.1"
                     /translation="MNVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEATRQFYS
                     LSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKTIVWTRGTTESINMVAQCYA
                     RPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVDLLPELITPR
                     SRILALGQMSNVTGGCPDLARAITFAHSAGMVVMVDGAQGAVHFPADVQQLDIDFYAF
                     SGHKLYGPTGIGVLYGKSELLEAMSPWLGGGKMIHEVSFDGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLADYDINQAESWSRSLATLAEDALAKRPGFRSFRCQDSSLLAFDFA
                     GVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAV
                     DRALELLVD"
     gene            4481..4708
                     /gene="ygdI"
                     /locus_tag="ACHY1N_002866"
     CDS             4481..4708
                     /gene="ygdI"
                     /locus_tag="ACHY1N_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HFS4045152.1"
                     /translation="MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVELDQ"
     gene            5059..5976
                     /gene="gcvA"
                     /locus_tag="ACHY1N_002867"
     CDS             5059..5976
                     /gene="gcvA"
                     /locus_tag="ACHY1N_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     regulator GcvA"
                     /protein_id="HFS4045153.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLP
                     SFAIHWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGEKPLKTPEDLAKHTLLHDASRRDWQTYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGVALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAAAEQEKFRFRYEQ"
     gene            5995..6390
                     /gene="ygdD"
                     /locus_tag="ACHY1N_002868"
     CDS             5995..6390
                     /gene="ygdD"
                     /locus_tag="ACHY1N_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HFS4045154.1"
                     /translation="MTSRFMLIFAAISGFIFVALGAFGAHVLSKTMGAVEMGWIQTGL
                     EYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAFVT
                     PVGGVSFLAGWALMLVGAIRLKRKGVSHE"
     gene            6383..7483
                     /gene="rlmM"
                     /locus_tag="ACHY1N_002869"
     CDS             6383..7483
                     /gene="rlmM"
                     /locus_tag="ACHY1N_002869"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010435097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HFS4045155.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIY
                     ECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYT
                     GYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVC
                     DMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINA
                     QIQARQLYHDREEVTVHVRRIWAAVGGRRDER"
     gene            complement(7527..8258)
                     /gene="fucR"
                     /locus_tag="ACHY1N_002870"
     CDS             complement(7527..8258)
                     /gene="fucR"
                     /locus_tag="ACHY1N_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HFS4045156.1"
                     /translation="MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQT
                     QGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDAS
                     STCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
                     LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEA
                     RIGHLDEVTHIISDERQVATSLVTA"
     gene            complement(8316..8738)
                     /gene="fucU"
                     /locus_tag="ACHY1N_002871"
     CDS             complement(8316..8738)
                     /gene="fucU"
                     /locus_tag="ACHY1N_002871"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016854 - racemase and epimerase activity
                     [Evidence IEA];
                     GO_function: GO:0042806 - fucose binding [Evidence IEA];
                     GO_process: GO:0042354 - L-fucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HFS4045157.1"
                     /translation="MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIR
                     ADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDI
                     IRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP"
     gene            complement(8740..10158)
                     /gene="fucK"
                     /locus_tag="ACHY1N_002872"
     CDS             complement(8740..10158)
                     /gene="fucK"
                     /locus_tag="ACHY1N_002872"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008737 - L-fuculokinase activity
                     [Evidence IEA];
                     GO_process: GO:0042355 - L-fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HFS4045158.1"
                     /translation="MKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENN
                     TWHQWSLDAILQRFADCCRQINSELTECHIRGIAVTTFGVDGALVDKQGNLLYPIISW
                     KCPRTAAVMDNIEQLISAQRLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFI
                     SSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIG
                     TLQNSAAAMLGLPVGIPVISAGHDTQFALFGAGADQNEPVLSSGTWEILMVRSAQVDT
                     SLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAP
                     GADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHFKA
                     SELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEAR
                     AQIHYQYRYFYPQTEPEFIEEV"
     gene            complement(10267..12042)
                     /gene="fucI"
                     /locus_tag="ACHY1N_002873"
     CDS             complement(10267..12042)
                     /gene="fucI"
                     /locus_tag="ACHY1N_002873"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HFS4045159.1"
                     /translation="MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEK
                     LRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPT
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALTWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQG
                     NSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVV
                     ATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLIN
                     SGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRL
                     TGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSA
                     WAAHGMDIEGQDYRACQNYGPLYKR"
     gene            complement(12075..13391)
                     /gene="fucP"
                     /locus_tag="ACHY1N_002874"
     CDS             complement(12075..13391)
                     /gene="fucP"
                     /locus_tag="ACHY1N_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015150 - fucose transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015756 - fucose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HFS4045160.1"
                     /translation="MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNL
                     NDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYA
                     LGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
                     FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAI
                     VLLVALLIMLTKFPALQSDNHSDAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTA
                     CWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALI
                     AMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTII
                     GGGIVTPVMGFVSDAAGNIPTAELIPALCFAVIFIFARFRSQTATN"
     gene            13938..14585
                     /gene="fucA"
                     /locus_tag="ACHY1N_002875"
     CDS             13938..14585
                     /gene="fucA"
                     /locus_tag="ACHY1N_002875"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008738 - L-fuculose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006004 - fucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HFS4045161.1"
                     /translation="MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTG
                     IPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVS
                     ILNRSIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVAQALKNRKATLLQHHGLIAC
                     EVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE"
     gene            14613..15761
                     /gene="fucO"
                     /locus_tag="ACHY1N_002876"
     CDS             14613..15761
                     /gene="fucO"
                     /locus_tag="ACHY1N_002876"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417279.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFS4045162.1"
                     /translation="MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQC
                     GVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLGVFQNSGADYLIAIGGGSPQDT
                     CKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHI
                     KAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRYNADFTGEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVG
                     IPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW"
     gene            complement(15816..16571)
                     /gene="xni"
                     /locus_tag="ACHY1N_002877"
     CDS             complement(15816..16571)
                     /gene="xni"
                     /locus_tag="ACHY1N_002877"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417278.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0017108 - 5'-flap endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0033567 - DNA replication, Okazaki fragment
                     processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HFS4045163.1"
                     /translation="MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTH
                     AVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNE
                     ADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
                     QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKL
                     ETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR"
     gene            complement(16683..18050)
                     /gene="sdaB"
                     /locus_tag="ACHY1N_002878"
     CDS             complement(16683..18050)
                     /gene="sdaB"
                     /locus_tag="ACHY1N_002878"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HFS4045164.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPGFIQDVNTHGRLMLANGQ
                     HEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQ
                     NSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRG
                     GIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVACD"
     gene            complement(18108..19397)
                     /gene="sdaC"
                     /locus_tag="ACHY1N_002879"
     CDS             complement(18108..19397)
                     /gene="sdaC"
                     /locus_tag="ACHY1N_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease SdaC"
                     /protein_id="HFS4045165.1"
                     /translation="METTQTSTIASKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFMSHQLGMTPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGDMAEQKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPVIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS"
     gene            complement(19954..21318)
                     /gene="ppnN"
                     /locus_tag="ACHY1N_002880"
     CDS             complement(19954..21318)
                     /gene="ppnN"
                     /locus_tag="ACHY1N_002880"
                     /EC_number="3.2.2.10"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase PpnN"
                     /protein_id="HFS4045166.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLR
                     DILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMP
                     LVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAF
                     SGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICT"
     gene            complement(21430..22278)
                     /gene="queF"
                     /locus_tag="ACHY1N_002881"
     CDS             complement(21430..22278)
                     /gene="queF"
                     /locus_tag="ACHY1N_002881"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708588.1"
                     /note="Catalyzes the NADPH-dependent reduction of
                     7-cyano-7-deazaguanine (preQ0) to
                     7-aminomethyl-7-deazaguanine (preQ1) in queuosine
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0043867 - 7-cyano-7-deazaguanine
                     tRNA-ribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HFS4045167.1"
                     /translation="MSSYANHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGL
                     KADNLPFHGTDIWTLYELSWLNAKGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQ
                     TRFNNWDEVRQTLERDLSTCAQGKVSVALYRLDELEGQPIGHFNGTCIDDQDITIDNY
                     EFTTDYLENATSGEKVVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRQIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNSDFVPST
                     TRLVRQ"
     gene            22346..22891
                     /gene="syd"
                     /locus_tag="ACHY1N_002882"
     CDS             22346..22891
                     /gene="syd"
                     /locus_tag="ACHY1N_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HFS4045168.1"
                     /translation="MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIIST
                     TEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQ
                     TWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGT
                     RKRTHLASNLAEFLNQLKPLL"
     gene            23513..23842
                     /gene="yqcC"
                     /locus_tag="ACHY1N_002883"
     CDS             23513..23842
                     /gene="yqcC"
                     /locus_tag="ACHY1N_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HFS4045169.1"
                     /translation="MTTHDRVRLQLQALEALLREHQHWRNDEPQPHQFNSTQPFFMDT
                     MEPLEWLQWVLIPRMHDLLDNKQPLPGAFAVAPYYEMALATDHPQRALILAELEKLDA
                     LFADDAS"
     gene            23842..24624
                     /gene="truC"
                     /locus_tag="ACHY1N_002884"
     CDS             23842..24624
                     /gene="truC"
                     /locus_tag="ACHY1N_002884"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HFS4045170.1"
                     /translation="MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDY
                     PLVEELDKIADKFAREDKGSQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLT
                     IHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS"
     gene            24642..25091
                     /gene="yqcA"
                     /locus_tag="ACHY1N_002885"
     CDS             24642..25091
                     /gene="yqcA"
                     /locus_tag="ACHY1N_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFS4045171.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDW
                     LPYQDKYVLVVTSTTGQGDLPDSIVPLFQGIKDSLGFQPNLRYGVIALGDSSYVNFCN
                     GGKQFDALLQEQSAQRVGEMLLIDASENPEPETESNPWVEQWGTLLS"
     gene            25526..26878
                     /gene="gudP"
                     /locus_tag="ACHY1N_002886"
     CDS             25526..26878
                     /gene="gudP"
                     /locus_tag="ACHY1N_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GudP"
                     /protein_id="HFS4045172.1"
                     /translation="MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYI
                     AAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGM
                     LLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
                     "
     gene            26880..28220
                     /gene="gudX"
                     /locus_tag="ACHY1N_002887"
     CDS             26880..28220
                     /gene="gudX"
                     /locus_tag="ACHY1N_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708582.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enolase C-terminal domain-like protein"
                     /protein_id="HFS4045173.1"
                     /translation="MTTQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTD
                     NAGHTGIGEAPGGEVIYQTLVDAIPMVLGQEVARLNKVVQQVHKGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLLGKALNVPVCELLGPGKQRETITVLGYLFYIGDRTKTD
                     LPYLENTPGNHEWYQLRHQKAMNSEAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAISLCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLSGAVRVAQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGNPTAIDTHWIWQEGDCRLTKNPLEIKNGKIAVP
                     DAPGLGVELDWEQVQKAHEAYKRLPVGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            28241..29581
                     /gene="gudD"
                     /locus_tag="ACHY1N_002888"
     CDS             28241..29581
                     /gene="gudD"
                     /locus_tag="ACHY1N_002888"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008872 - glucarate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0019394 - glucarate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HFS4045174.1"
                     /translation="MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGDRKAT
                     PLPYQSQPDDSCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAQRFPQARITLDPNGAWSLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQV
                     PEKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            complement(29813..32569)
                     /gene="barA"
                     /locus_tag="ACHY1N_002889"
     CDS             complement(29813..32569)
                     /gene="barA"
                     /locus_tag="ACHY1N_002889"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HFS4045175.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFH
                     LDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYI
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTL
                     NIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNR
                     GSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYS
                     PTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKL
                     KQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKL
                     IGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPE
                     VNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGL
                     VDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREAS
                     KILG"
     gene            32626..33927
                     /gene="rlmD"
                     /locus_tag="ACHY1N_002890"
     CDS             32626..33927
                     /gene="rlmD"
                     /locus_tag="ACHY1N_002890"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFS4045176.1"
                     /translation="MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGL
                     LPQENAEVAVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQR
                     SKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVK
                     QCPILVPQLEALLPKVRACLGSLQVMRHLGHVELVQATSGTLMILRHTAPLSSADREK
                     LERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVA
                     RALEWLDVQPEDRVLDLFCGMGNFTLPLAKQAASVVGVEGVPALVEKGQQNARLNGLQ
                     NVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPA
                     TLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK"
     gene            33975..36209
                     /gene="relA"
                     /locus_tag="ACHY1N_002891"
     CDS             33975..36209
                     /gene="relA"
                     /locus_tag="ACHY1N_002891"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP diphosphokinase"
                     /protein_id="HFS4045177.1"
                     /translation="MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQ
                     QTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKS
                     VVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRD
                     ITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGS"
     gene            36287..36535
                     /gene="mazE"
                     /locus_tag="ACHY1N_002892"
     CDS             36287..36535
                     /gene="mazE"
                     /locus_tag="ACHY1N_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MazE"
                     /protein_id="HFS4045178.1"
                     /translation="MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLII
                     EPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW"
     gene            36535..36870
                     /gene="mazF"
                     /locus_tag="ACHY1N_002893"
     CDS             36535..36870
                     /gene="mazF"
                     /locus_tag="ACHY1N_002893"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease MazF"
                     /protein_id="HFS4045179.1"
                     /translation="MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTG
                     MCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLI
                     KAKINVLIG"
     gene            36941..37732
                     /gene="mazG"
                     /locus_tag="ACHY1N_002894"
     CDS             36941..37732
                     /gene="mazG"
                     /locus_tag="ACHY1N_002894"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HFS4045180.1"
                     /translation="MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVL
                     DAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFAD
                     SSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWT
                     TLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQK
                     ANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL"
     gene            37960..39597
                     /gene="pyrG"
                     /locus_tag="ACHY1N_002895"
     CDS             37960..39597
                     /gene="pyrG"
                     /locus_tag="ACHY1N_002895"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine hydrolyzing CTP synthase"
                     /protein_id="HFS4045181.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQM
                     AVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVE
                     TRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARH
                     VANMENANSTEFVPECKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVD
                     DSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK"
     gene            39685..40983
                     /gene="eno"
                     /locus_tag="ACHY1N_002896"
     CDS             39685..40983
                     /gene="eno"
                     /locus_tag="ACHY1N_002896"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFS4045182.1"
                     /translation="MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEN
                     KSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA"
     gene            complement(41043..41915)
                     /gene="ygcG"
                     /locus_tag="ACHY1N_002897"
                     /pseudo
     CDS             complement(41043..41915)
                     /gene="ygcG"
                     /locus_tag="ACHY1N_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417258.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YgcG family protein"
BASE COUNT        10469 a        10108 c        11109 g        10280 t
ORIGIN      
        1 ttattgcccg ggcttccaca aaaaattatt aatttttcta ctaattaaaa aatgtgtgct
       61 ttttgtacaa taattatata agtgtagcct ccagttgtga tattgaaatg ttaacataat
      121 caaaacaaat tgatttatag aatatgtaag tgaagttcat tggtggggta tatatttaat
      181 atataaataa gatggatggc tttgattggg ggggatcaac ggtttactca ttgtttcagg
      241 cttcactgaa acggataagg aagcgtaaaa acgaaaaaac cgcaagctaa aggtagcgtt
      301 gcggtttctg atattctaat aaattggttg cgggggccgg atttgaaccg acgaccttcg
      361 ggttatgagc ccgacgagct accaggctgc tccaccccgc gtccgtggat gcgcactata
      421 ctccgctcgc gttttcatgc aacctttttt ttaccccgat cacggattta gcatgatttt
      481 gaacaaaaac aaaccactaa agcctatttt ttgtacaaaa tttgcgtcag ggagaggctg
      541 ctcatttcat taaacgcggc ggtttgttat cttcgttgcg ccttattttt taacctgaag
      601 aagagaacaa tgaaaggacg ttgggtaaag taccttctta tgggcacggt tgtggcaatg
      661 cttgccgcct gctcttccaa accaaccgat cgcggacagc aatataaaga cgggaaattt
      721 acccagcctt tctctctggt gaaccagcca gatgccgttg gcgcgccgat taacgccggt
      781 gattttgccg agcaaattaa ccatatccgt aattcgtcac cgcgtctgta tggcaaccag
      841 agtaatgttt ataacgcggt gcaagagtgg ctgcgcgcag gcggtgatac ccgcaatatg
      901 cgccagttcg gcattgatgc ctggcagatg gaaggtgccg acaactatgg taacgtgcag
      961 tttacaggct attacacgcc ggtaattcag gcgcgccata cccgccaggg cgagttccag
     1021 tatcctattt accgtatgcc gccaaaacgt ggtcgtctgc cgtctcgtgc ggagatctac
     1081 gcaggggcgc tgagtgataa atatattctc gcttacagca actccctgat ggataacttc
     1141 attatggatg tgcagggtag cgggtatatc gactttggtg atggcagtcc gcttaacttt
     1201 ttcagctatg cagggaaaaa cggtcatgcc tatcgcagca ttggtaaggt gctgatcgac
     1261 cgtggcgaag tgaaaaaaga agatatgtcg atgcaggcga ttcgtcattg gggcgaaaca
     1321 cacagtgaag ccgaggttcg cgagctgctg gaacagaacc cgtctttcgt tttctttaaa
     1381 ccgcaatctt ttgcaccggt gaaaggggca agtgcggtgc cgctggttgg ccgtgcttct
     1441 gttgcctccg atcgttcaat tattccgcca ggtactacct tgctggcaga agtgccgctg
     1501 ctggataata acggcaaatt taacggtcag tacgaattgc gtctgatggt ggcgctggat
     1561 gtcggtggcg caatcaaagg ccaacacttc gatatctatc aagggatcgg gccggaagcc
     1621 ggacatcgcg caggttggta caaccactat ggacgtgtct gggtgctgaa aaccgccccg
     1681 ggcgcaggta acgtctttag cggctgatgt gttattctgt ataccgtttt tacggatacg
     1741 ccagggtgag ggataacctc acccttttta attctgaggt gctatgtctg tggtaattag
     1801 tgatgcatgg cgtcagcgtt ttggtggcac agcgcgtctg tatggtgaaa aagcgttgca
     1861 actgtttgct gacgcgcata tttgtgtggt tggtatcggt ggtgtcggtt cctgggcggc
     1921 ggaagcgctg gcgcgcacgg ggattggcgc aatcacgctt atcgatatgg atgatgtgtg
     1981 cgtcaccaat accaatcggc aaattcacgc tctgcgcgat aacgtcgggc tggcaaaagc
     2041 ggaagtcatg gcggagcgta ttcgccagat taacccggag tgccgtgtaa cggtggtgga
     2101 tgatttcgtg acgccggata acgtagcgca gtatatgagc gtgggttatt cgtacgtgat
     2161 tgatgccatt gatagtgtac ggcccaaagc ggcgctgatt gcttattgtc ggcgcaataa
     2221 aatcccgctg gtcacgaccg gtggcgcggg tgggcagatt gacccgacgc agattcaggt
     2281 taccgatctg gcgaaaacga ttcaggatcc gctggcggcg aagttgcgcg agcgcctgaa
     2341 aagcgatttt ggcgtagtga aaaacagtaa aggtaagctc ggcgtcgatt gcgtgttttc
     2401 tactgaagcg ctggtgtacc cgcagtcaga cggtactgtg tgtgcgatga aagccacggc
     2461 agaagggccg aagcggatgg attgtgcatc tggatttggc gcggcaacga tggtgaccgc
     2521 cacctttggg tttgttgcgg tttctcatgc gctgaagaag atgatggcga aagcggcgcg
     2581 tcagggttaa acaatcaggt cggatgcgac gcgaacgtct tatccgacct ggttctgtgc
     2641 ttaaacctgc ttcgccgcag cgataatcgc ctcgcttaac gcattcaacc cctggctgcg
     2701 tgaggcgcta agctgtgcac gcaatcccag ctcatcaaac aatgccagcg gcgactgtgc
     2761 ctgcaattcg gcgacggttt tcccctcaac ggcagtcaac aacaccgcca acaggccgcg
     2821 cacaatgcgc ccttcgctgt cgccaaagaa gtgcatttta ccgttttcag tcacggtata
     2881 tcccagccag acgcggtttt cgcatccggc aatctcttta gcctgcgctt ttaactcgtc
     2941 tggcaaagcc ggaagctgtt tccccagcat gatcaactgg cgatatttat cttcccattg
     3001 cgacaacggt gcgaaggtat tgcgtaacgt ttctgcggtt acggttgtgc cgaacggatg
     3061 tccggcgaat tgcgggtttg tcattaatcc accaataatt ccagcgcgcg gtcaacggca
     3121 ttcaccagcg catccacatc actctttgta ttatatggcg caaaagaggc gcgcagtgtg
     3181 ccggttacgc ctaattctgc cagtagcggc tgagcgcaat gctgcccggc ccgcagggca
     3241 ataccgtact ccgccagcag cgtcaccata tcgctatgat gaacgccagc aaaatcaaag
     3301 gccagcaggc tggaatcctg gcagcggaat gaacgaaagc cgggacgttt cgccagcgca
     3361 tcttccgcca gcgttgctaa gctacggctc cagctttcgg cctggttgat atcgtaatct
     3421 gccagccatt ccagcgccgc gcttaatcct atgacaccag cgacatttgg cgttccagct
     3481 tccagtttcc acggcgcaga ttgagtcgtg aagccgtcaa aactcacttc gtgaatcatt
     3541 ttgccgccac ccagccaggg cgacatcgct tccagcagtt ctgatttgcc atacagcacg
     3601 ccgatacccg tcgggccata cagtttgtga ccagagaaag catagaaatc gatatctagt
     3661 tgctgaacat ctgcggggaa atgcaccgcc ccctgagcac catcaaccat caccaccatc
     3721 ccggctgaat gagcaaaggt aatcgctcgc gccagatccg ggcaaccgcc agtaacgttc
     3781 gacatctgac ccaacgccag aatccgacta cggggagtaa tcagttctgg caacaaatcg
     3841 acatccggca gtcgctgcgc attaagcggc aatttcacca ctttggctcc agtttgttgg
     3901 gcgaccatca gccaggggac gaggttagcg tggtgttctg ccacgctgac aataatctca
     3961 tcgcccggtt gcagacgcgg acgcgcatag cattgtgcca ccatgttgat ggattcagtg
     4021 gtgccgcgcg tccagacgat agttttatca tccggtgcat tcagtaattg cgccactttc
     4081 tctcgtgcag cttcataacg cgcggtcagg cgttgggctt cggcaaactg gctgcgatgg
     4141 acgtttccgg cgctcaggct gtaaaactgt cgggtggctt caaccacggc ttcaggttta
     4201 agcgcggtcg cggcgctgtc gagatagacg cccgcatcct gtagagcggg aaactgggcg
     4261 cgaaactgcg cgggattaaa aacgttcatg gtactcctcg gcttgatgca ccgatcgtga
     4321 cgcaaaattc actttgatac aaggagagtg ctaaccatca gaattatctg gatatcctgg
     4381 cgaagccgcg taagtaacat atgctgaata gtgttaggcg ttaattttag cctgttaatc
     4441 aatactatta agatttatta attgctttaa ggagaagatg atgaaaaaga ctgccgcaat
     4501 tatttctgcc tgtatgctga cttttgccct gagcgcctgt tccggttcga actatgtgat
     4561 gcacaccaat gacggacgta ccatcgtctc tgacggcaaa ccacagactg ataacgatac
     4621 cggtatgatt tcgtataaag acgctaatgg caacaaacag cagatcaacc gtactgacgt
     4681 gaaagagatg gtcgaactgg atcagtaatt cacgatcgca aggtaaaaaa aagcaccgca
     4741 attaggcggt gctacattaa tcactatgga cagacagggt aaatgtacag gaagtgaaaa
     4801 aaggtagctt tgctaccatg gtctgaatcg cagaccaatt gcaaacacaa caacacaaca
     4861 tcacaaccgt aagccaaaag ttcaccagaa cacgcattcc gataaaactt ttcgttccgg
     4921 ctcaggaagt gccgccacta taggtatttg ctggtagaag ctcaacggac aatttataat
     4981 ggctcagatt aaaaaaacta ataggttaca cagtgtgatc taattgttaa attcatttaa
     5041 catcaaagtt taaaagccat gtctaaacga ttaccaccgc taaatgcctt acgagttttt
     5101 gatgccgcag cacgccattt aagtttcact cgcgcagcag aagagctttt tgtgacccag
     5161 gccgcagtaa gtcatcaaat caagtctctt gaggattttt tggggctaaa actgttccgc
     5221 cgccgtaatc gttcactcct gctgaccgag gaagggcaaa gctatttcct cgatatcaaa
     5281 gagatatttt cgcaattaac cgaagcgacg cgtaaactcc aggcccgtag cgccaagggg
     5341 gcgttgacgg tcagtttact ccccagtttc gccattcatt ggttggttcc gcgactttcc
     5401 agctttaatt cagcttatcc gggaattgac gttcgaatcc aggcggttga tcgtcaggaa
     5461 gataagctgg cggatgatgt tgatgtggcg atattttatg gtcggggcaa ctggccgggg
     5521 ctacgggtgg aaaaactgta cgccgaatat ttattgccgg tgtgttcgcc gctactgctg
     5581 acaggcgaaa aacccttgaa gaccccggaa gatctggcta aacatacgtt attacatgat
     5641 gcgtcacgcc gtgactggca gacatatacc cgacagttgg ggttaaatca tatcaacgtt
     5701 cagcaagggc caatttttag tcatagcgcc atggtgctgc aagcggctat tcacgggcag
     5761 ggagtggcgc tggcaaataa cgtgatggcg caatctgaaa ttgaagccgg acgtcttgtt
     5821 tgcccgttta atgatgttct ggtcagtaaa aacgcttttt atctggtttg tcatgacagc
     5881 caggcagaac tgggtaaaat agccgccttt cgccaatgga tcctggcgaa agccgctgct
     5941 gaacaagaaa aattccgctt tcgttatgaa caataattta cgtagggtac gaccatgacc
     6001 agccgtttta tgctgatttt cgccgccatt agcggcttca tttttgtggc tctgggcgct
     6061 tttggcgcgc atgtgttaag taaaaccatg ggggccgttg agatgggctg gatccagacc
     6121 ggcctcgaat accaggcgtt tcatacgctg gcgatcttag gtctggcggt ggcaatgcag
     6181 cgtcgcatca gtatctggtt ttactggagt agcgttttcc tcgcgttagg cacggtgctg
     6241 ttcagcggca gcctttattg cctggcactg tcccatctgc gtttgtgggc gtttgtcact
     6301 ccggttggcg gcgtgagctt ccttgcgggc tgggcgttaa tgttagttgg tgctatccgt
     6361 ttaaagcgca agggcgtaag tcatgaataa ggttgtattg ctgtgccgtc cgggctttga
     6421 aaaagagtgc gccgcagaaa ttaccgataa agccggccag cgggaaattt tcggttttgc
     6481 ccgcgtgaaa gagaatgcgg gttatgtcat ttatgaatgt tatcaacctg atgatggcga
     6541 taagttaatc cgtgagctgc cgttcagttc attaattttt gcccgccagt ggtttgtggt
     6601 gggggaactc ctgcagcatt tgccgccaga agatcgtatt acccccattg tcggcatgtt
     6661 acagggcgta gtagagaagg gcggtgaact gcgtgttgaa gttgccgata ccaacgaaag
     6721 caaagagttg ctgaaattct gccgtaaatt caccgtgccg ctacgcgctg ccttgcgcga
     6781 tgccggggtg ctggcgaact atgaaacgcc gaagcgtccg gttgtgcatg tattcttcat
     6841 tgcaccaggt tgctgctata ccggttactc atacagcaac aataattcgc cgttctatat
     6901 gggcattccg cgcctgaaat ttccggcaga tgcgccgagt cgttccacac tcaaactgga
     6961 agaggcattt catgtgttta ttcctgcgga tgagtgggat gaacgcctgg cgaacgggat
     7021 gtgggcggtg gatttgggcg cttgcccagg cggctggacc taccaactgg tgaagcgcaa
     7081 catgtgggtt tattccgtcg acaacggccc gatggcgcaa agtctgatgg ataccgggca
     7141 ggtgacgtgg ctgcgggaag acggtttcaa attccgtccg acacgcagca atatctcctg
     7201 gatggtatgc gatatggttg aaaaaccggc taaagttgcg gcattgatgg cgcagtggct
     7261 ggttaatggc tggtgccgtg aaaccatttt caatctcaaa ctgccgatga aaaaacgcta
     7321 cgaagaagta tcacacaatc tggcgtatat tcaggcacag cttgatgaac atggcataaa
     7381 tgctcagatt caggcgcggc agttgtatca cgatcgcgaa gaagtgacgg tgcacgtccg
     7441 ccgcatctgg gctgcggtgg gtggtcgtcg cgacgagcga taacaggcaa ggccggggcg
     7501 tcgtctccgg cctgctaccc tttccgtcag gctgttacca aagaagttgc aacctggcgc
     7561 tcatcagaaa taatgtgcgt tacctcatcc agatgcccga tgcgggcttc ccctgaacga
     7621 ttaaatttac ttttatcaat caataacaac gattgcgcgg cacgttttaa tagcatcgat
     7681 ttgtaatcag cgttgatggc attggagtcc cacagtgcgc cgctgctatc gatcccttca
     7741 caagaaaaaa taaacagatc gatttccagc gatttaagtt gggaaatcag cgagggattg
     7801 acgtaacagc catatttgcg ctcaagtgtg ccgccggaac tgatcagttg aatgcgttcg
     7861 cgtttaccga gttcatggca aatcggatgg ctattggtga agacctgaat gttgatgtca
     7921 ggcaactggc gtgccagata ccagcaagtt gaactggcgt ctaaggctat caccatccct
     7981 tcttcaatcc acgcgagcgc ctcgcgcgcg atatctgctt tatgcgcata atggcttttc
     8041 agccggatgt gaaagggatc gccactgtct tgattttgac ggtggatata tttagcgcgt
     8101 ccatgattgc gcagaatttt accctgcgtc tgtaattcat tgagatcgcg acgaatggtt
     8161 tctttactga cctttagctg ttcagagaga gcttccgtgg tcaggctggt atggttcagc
     8221 agcaggtcga ctatcgcttg ctggcgtgcc gctttcatat ttttcacccc atcattcgat
     8281 aaccgcccgc gtcatgcggg cgtaccggta tgagattacg gtgttacccc tttttttaaa
     8341 agaatattcc cgtacttcgc tcgttcgcct gtgataacga tcgcaaaggc tttttgcgcc
     8401 cgttcataaa acgcaaaacg attgatgcgg atgatgtcag gacacggggc ttgtagtgaa
     8461 agcgcattac ggtaacgtcg ttctacttca ggatcgagag tgtcaccttc taccgctgcc
     8521 atcatcacca gcggcggggc ataactgtcc agctcaaata acgggataat cgcctggagc
     8581 aagtcgctca ccaacaggcc atcagcgcgg atcacctgcg gtcccatcga atgggcggga
     8641 aagtgagcat cggaaaaaat aatttcatct ccatgtccca tctctgccag cactttcaat
     8701 agttcgggag aaattaacgg cgaaattgtt ttcagcattt cacacttcct ctataaattc
     8761 aggttcagtt tgcgggtaga aataacggta ctgataatga atctgtgcac gggcttcttc
     8821 cgggctgttg aattccccta cgccatacca accgaacagc gcagctcctg cgacggtcgt
     8881 ttcggcatcg tcgagaactt ttaccggaat atcaagcata ttggctttaa tctgattcca
     8941 caatgtgttg cgacttcctc caccgactaa caataattca gaggccttaa agtgcccgat
     9001 tttttccagc atctgtagat tgcgctgtaa ttgcgcagtt aacccttcca gcgccgcgcg
     9061 atagaaatgc ccccgcgtgg tattaagcgt cactccttgc cagccagcgt tctgacacga
     9121 caataaatca cactgcattt ttacgccatc cgcgccaggc gcgatcagac gagcttcttc
     9181 aatcaacatt tgccagggtg tttcagccgt ccagaacagt tttctcaccc attccagcac
     9241 gccggatgcc agccattgca tacctgggtt atacaaccct gcctggctat ccagttcgca
     9301 ggtggaaccg gcgtactgac ttaacagcga agtatcaacc tgggcgctac ggaccattaa
     9361 aatttcccat gtaccggaag agagcacggg ttcattttgg tcggcaccag cgccaaaaag
     9421 ggcgaactgg gtatcgtgac ctgcggaaat caccggtatg ccaacgggta agccgagcat
     9481 tgctgcggcg ctgttctgta gcgtaccaat ctgttcaccc gcttccacca gacgagggaa
     9541 gagtcggcgt ggaataccgg tggcttgtaa aatttgcgga ctgaaatcgc gttgctggat
     9601 atccagcatc tggctggttc cggccatcgt gatatcagta gtgaattcgc cggttaaacg
     9661 gtggttaatc agcgacgaaa taaagagcca ggcgtgcgcg cgttccagca gttgtggatg
     9721 attttctttc aaccacacca acttatataa cgtattgaaa ctaaaggctc cgacgccaga
     9781 aatagcctgc aaccgctgtg cggagatcaa ctgttcaata ttgtccataa ccgctgctgt
     9841 tcgcggacat ttccagctaa tgatcggata gagcagattg ccttgcttat ctaccagagc
     9901 gccatccaca ccaaaggtgg tgacggcgat accgcggatg tggcattcag tcagttcact
     9961 attgatttgc cgacagcaat cagcaaagcg ttgcaaaatg gcgtctaaag accactggtg
    10021 ccaggtgttg ttttccatcg cgatatcgct ggcattaggc gttgaggcgc gggcaacaat
    10081 ttttccctgc cgattaaccg cgatggccct gacattggtc gcgccacagt cgagtaccag
    10141 gataacttct tgtttcataa tcgctcctgc aatatagccg gataacattg cttatccggc
    10201 taaccactct tgcttgttca ggcccggtag ccggagcgac cgggcatcac atcagggagt
    10261 aatgtattaa cgcttgtaca acgggccgta gttctggcaa gcgcggtaat cctggccttc
    10321 aatatccatg ccgtgcgcag cccaggcaga aggacgatac actttggtct cttcaacgtt
    10381 gtgcatacat accgggatac gcagcatgga ggcgagagtg ataaagtctg cgccaacgtg
    10441 gccgatggtc agaaccccat ggttagcgcc ccagttcgcc attaccgagt acacatccgt
    10501 aaacggccct ttaccggtga ggcgcggtgc aaaccaggtg gttggccagg ttgagttggt
    10561 gcgtttgttg aggatgtcat gcacatcctt cggcaattcc acgctccagc cttccgcgat
    10621 ttgcagtacc ggtcccaggc ctttgatgat gttgacacgg gtcatggtga acgggacgcc
    10681 gccttcggta aggaagcggg aagagtaacc gccgccacgg aagtattcgt ggatcgccgg
    10741 gcaccattcg gtagcggcga ggcaagcgtc agcctcttgc tgagagattt cccagtgcgg
    10801 cttcatcgtc gggttacctt cgctgtcgcg ttgtttacag gaaccgtcca gcgcagcaga
    10861 accggagttg atcaaatgga tgatgccgtg ttctgccagt ccatcgagtt tatgccccgt
    10921 tacacgctca attgcttctg gtgaccagta ggtacgcaca tcggcaaata cctgagcggt
    10981 gccggtgagc tggtgaccca ttagcattgc cacgccgtta agactgtcgt tttcggtcgc
    11041 cacgacaaag ggttcgcgca cgccattcca gtcaaatgaa ctgttaagga tcgcttcggc
    11101 ggtgtcacca ttgggatatt gatcggtcca gtgacgttgc ccctggaagc ccgcagcgat
    11161 ggcgttgtag ccaagtgatt cttccacgcg accaatatcg gccagtttgc tgttgccttg
    11221 catcatgtcg cggatacaca tcgccatcag taaactttcg cgcagaactg cgcggctttg
    11281 ctcggcattg cgttgatact gtttgttatt ttcatcttcg ccatagcgga agtttttatc
    11341 agcccaggtc agtgccattt ccagttcggc ttcgtcgtaa atcttctgat cgatacggcg
    11401 acgcagttcg gtcatatcca ccgcctggac tttcattccc agccaggatt caaagaagtt
    11461 gtgatcaaca atagaaccgg cgatacccat cgaaacgccg cccagcgaca gatagctttt
    11521 acctttcatg ctggcgacgg ccaaaccggc gcgggcaaag cgcagcagtt tttcttcaac
    11581 atcggcagga atcgatgtgt catcggcatc ctgaacgtca tgaccgtaaa tggagaatgc
    11641 cgggatgcct ttctggctgt gagctgccag agccgctgcc aggtaaacag cgccgggacg
    11701 ttcagtgccg ttaaagcccc aaatggcttt cgggcgggtt ggatccatgt cgatggtttc
    11761 actgccatag caccagcaag gcgttaccgt aatggtgagg cctacattct gactgctgaa
    11821 tttttcttcg caagcagcgg cttcagccat acccgcgata caggtatcgg aaatgacaca
    11881 ctcgacggca gctccgcagg catggcgcag tttctcggtc agcagtgcgg ccgtagcttt
    11941 cgccatattc attgtttgtt cttcaagcga ctcacgaaca cccatgcgac gaccgtcaat
    12001 aaccgggcgg ataccaattt tcggtaagct gatttttttc attacagatt cctcacttta
    12061 ttcggaaaat atgttcagtt agttgccgtt tgagagcgga aacgggcaaa gataaagatg
    12121 accgcgaagc agagtgcggg gatcagttca gcagtgggga tgttgcccgc cgcgtcactg
    12181 acaaaaccca tgaccggagt gacaataccg ccgccaatga tggtcataac gatgaaggac
    12241 gaaccgtatt tggtgtcctg gccgagattc ttaatgccca gcgagaagat tgttgggtac
    12301 tgaatcgaca taaaggcgct gcataaagtc agggctatta agcccacatg accgccagcg
    12361 aaggctgaga tcaggcacag tgccatagcg attaatgcgt aggcggccag gactttgtgt
    12421 ggtgcgaagc gactgatgag ccaggtaccg gtgaaacgac caataaagaa gcacaccatg
    12481 gttccggtta aatagttagc ggcaaagcct gcagtcatac ctggaatttc ttctacagcg
    12541 tagcgaatca aatagctcca gcaggccgtt tgtgcgccaa cgtagcagaa ttgcgctaat
    12601 accgcccagc gccagtgacg aatacgcgcc agacgagaaa gcgatgcgga gaacgatcct
    12661 tgtttggcgt cactgtgatt atcactctgc aatgccggga atttcgtcag catgatcagc
    12721 agggcgacca gtaacacgat agccacgatg atcatataag gtgtctgtac cgataatacc
    12781 aggctgtgtt tatacgcact caattgctct ggagacattt tatcgagaac gtcttgcgat
    12841 tgatgtggca cgttagacaa aataagactt tgcccaaaga caaccgcgat aattgcgcca
    12901 aacgagttaa atgtttgcgc aagatttaag cggaagtgac cactgctttc cggccctaat
    12961 accgtaacaa aagggtttgc ggcagtttcc agacaaccta atccggctgc aataataaat
    13021 aggccaacta aaaataaggt gtagttcatt atttctgcag cgggccagaa taatgcagcg
    13081 cccaaggcat ataaaaataa tccggtaata atccctgctt tataactgag ttttttcatc
    13141 aatatcccag cagggattgg gataatgaaa taaccaaagt aaaaggccga ttggatcagg
    13201 ccagcctgga aatttgtcag cgtaaaagcc tgctggaatt gaggtaataa aatgtcgtta
    13261 aggttattgg ctaccgccca aagaaaaaac agtgagcaca gcagcgcgaa tggaataatg
    13321 taacttctgc tttgccctgc atctttatct accgcacggt aactctgcgt ttgtattgat
    13381 gtgtttccca tagcatcctc ttaggttcag aagcttaagc acgtaatcgg ttatgttttc
    13441 aaaagtgcaa aaccagcgag ttcgggcttc atatcagtga atatttgcct gtctgaaatg
    13501 aactcatgga ttcattttca aataaaaaac gctctgtaat atgacggcgg tcacacttat
    13561 tagctggaag gtgactttat gtgactacca tcactttaat aatcgaaatt tcatgcccgt
    13621 ttcagaaaat aaattataaa aaacacaaac cagatgaccg tattaattgt ttatgccgaa
    13681 aacgggcatt cctggcttga gtgaatagaa aaatgaccgt tttgataaat atttttaaga
    13741 gcggtcattt ttaatggggt tataaaaaga gaacttgcag ttatttactg tgattagttg
    13801 aaccaggtca caaaatataa gcttgtgaat ttctttctgg ttaatcagga agaagatggt
    13861 gggtaattaa acggctaatt caatagtgtg aaaggaacaa cattattgcc ctgttttgaa
    13921 tcagagagag gtagctaatg gaacgaaata aacttgctcg tcagattatt gacacttgcc
    13981 tggaaatgac ccgcctggga ctgaaccagg ggacagcggg gaacgtcagt gtacgttatc
    14041 aggatgggat gctgattacg cctacaggca ttccatatga aaaactgacg gagtcgcata
    14101 ttgtctttat tgatggcaac ggtaaacatg aggaaggaaa gctcccctca agcgaatggc
    14161 gtttccatat ggcggcctat caaagcagac cggatgccaa cgcggttgtt cacaatcatg
    14221 ccgttcattg cacggcagtt tccattctta accgatcgat ccccgctatt cactacatga
    14281 ttgcggcggc tggcggtaat tctattcctt gcgcgcctta tgcgaccttt ggaacacgtg
    14341 aactttctga acatgttgcg caggctctca aaaatcgtaa ggcaactttg ttacaacatc
    14401 atgggcttat cgcttgtgag gtgaatctgg aaaaagcgtt atggctggcg catgaagttg
    14461 aagtgctggc gcaactttac ctgacgaccc tggcgattac ggacccggtg ccagtgctga
    14521 gcgatgaaga gattgccgta gtgctggaga aattcaaaac ctatgggtta cgaattgaag
    14581 agtaatttcg taaagcaaca aggagaagga tgatggctaa cagaatgatt ctgaacgaaa
    14641 cggcatggtt tggtcggggt gctgttgggg ctttaaccga tgaggtgaaa cgccgtggtt
    14701 atcagaaggc gctgatcgtc accgataaaa cgctggtgca atgcggcgtg gtggcgaaag
    14761 tgaccgataa gatggatgct gcagggctgg catgggcgat ttacgacggc gtagtgccca
    14821 acccaacaat tactgtcgtc aaagaagggc tcggtgtatt ccagaatagc ggcgcggatt
    14881 acctgatcgc tattggtggt ggttctccac aggatacttg taaagcgatt ggcattatca
    14941 gcaacaaccc ggagtttgcc gatgtgcgta gcctggaagg actttccccg accaataaac
    15001 ccagtgtacc gattctggca atccccacca cagcaggcac tgcggcagaa gtgaccatta
    15061 actacgtgat cactgacgaa gaaaaacggc gcaagtttgt ttgcgttgat ccgcatgata
    15121 tcccgcaggt ggcgtttatt gacgctgaca tgatggatgg tatgcctcca gcgctgaaag
    15181 ctgcgacggg tgtcgatgcg ctcactcatg ctattgaggg gtatattacc cgtggcgcgt
    15241 gggcgctaac cgatgcactg cacattaaag cgattgaaat cattgctggg gcgctgcgag
    15301 gatcggttgc tggtgataag gatgccggag aagaaatggc gctcgggcag tatgttgcgg
    15361 gtatgggctt ctcgaatgtt gggttagggt tggtgcatgg tatggcgcat ccactgggcg
    15421 cgttttataa cactccacac ggtgttgcaa acgccatcct gctaccgcat gtcatgcgct
    15481 ataacgctga ctttaccggt gagaagtacc gcgatatcgc gcgcgttatg ggcgtgaaag
    15541 tggaaggtat gagcctggaa gaggcgcgta atgccgctgt tgaagcggtg tttgctctca
    15601 accgtgatgt cggtattccg ccacatttgc gtgatgttgg ggtacgcaag gaagacattc
    15661 cggcactggc gcaggcggca ctggatgatg tttgtaccgg tggcaacccg cgtgaagcaa
    15721 cgcttgagga tattgtagag ctttaccata ccgcctggta aatgcgctga tgtgataatg
    15781 ccggatacga cgtttgcggc gtatccggct cgccgttacc gtaccaaccg caattgctgt
    15841 aaattgccgt cgatatgcaa atcggtttgt aagcgggcaa tatcgcggca cagaaacgcc
    15901 atctctttat gggtttctaa ttttttgcgc cacttttcgg caaccgcatc cagattctca
    15961 tatatccctt ccagactctg aaactcgacc agcagctgcg tggcgctttt tggtccgatt
    16021 cccgcaacac ccggtacctt tgaactgctg atccccgcaa gtccccagta atcgggcaac
    16081 tgctgcggtt gaacgccaaa ttctttatcg ataaatggcg catccagcca acgtttctgg
    16141 aagtaatcac gaatacgtaa tgtcggtgaa agtaactgac agtagccttt atctgtcgaa
    16201 acaatcgttg cctgatgccc ggcctgtgtc actttgaccg ccagcgtggc ggctaagtca
    16261 tcggcttcgt tgccgctggt tgaccagcac gggacgccgc gttgctcaaa ggcggcgcgt
    16321 aatgcaggca tctcgtcgtg caactcttcc ggcattggcg gtcgacccgc tttgtaatct
    16381 ggtaaacgct gatgacgcca gccgctactg cggttttcat catcaaaaac ggcgaccgcg
    16441 tgggttggct ggctgtgcat aatgagctga tcgagcgcat gctgacaggt ttcgacacag
    16501 ggcgatccct gaacggcatg aatgcgacga ataagattca gtgcatcgac aataagcaaa
    16561 tgaacagcca cgataacccc cttaaagatc aggcgataag ggtaacattc gatgccggaa
    16621 caggctacgg ctggatgaga aatcgggaag aggcctcgca aaacgaggcc tctggagagc
    16681 gattaatcgc aggcaacgat cttcattgcc aggccgccgc gagaggtttc gcggtacttg
    16741 gcgttcatat ctttacctgt ttcgtacatg gtttcgataa ctttatcgag gcagacgcgc
    16801 ggctcgctgg tacggcgtag cgccatacgt gcggcgttca ccgcttttac tgccgcaatg
    16861 gcgttacgct cgatgcatgg cacctggacc tgtccggcga ccgggtcaca cgtcagaccg
    16921 aggttgtgct ccatggcgat ttccgccgcg atgcacacct gcgccgggct tgcacctaac
    16981 agttctgcca gaccagccgc cgccattgag cacgccacac caacttcacc ctggcagccg
    17041 acttcagcac cagaaattga cgcgttcatc ttataaagag aaccaatggc actggctacc
    17101 agcaggtaac gagccagtga gttagcgttc acttcgcgga taaacttgtc gtagtacgcc
    17161 agcactgccg ggataatccc gcacgcaccg ttagtcggcg cagtcaccac gcgtccgcca
    17221 gcagcgttct cttcgttcac tgccagtgca aacatgttga tccagtcaac aaccgccatc
    17281 gggtcagtgg tggttttatc ctggctgacc agcatccggc gtagtgccgc agcacggcgt
    17341 ggaacgcgca gtttgccagg caacacgcct tcggtggaaa taccgcgctc aataccgcca
    17401 cgcatgactt cccatacgtt cgccaggtgc tgttccagct cttctttgct gtgcagcgcc
    17461 agctcatttt tcatcatcag gccagagagt gacagcccgg tttcctgaca atgtttttgc
    17521 agatcggctg ctgaactgta cggataagga acttcaaccg gtgcgctatt ctgctggcca
    17581 aaatgctctt catcaacgat aaagccaccg ccaatagagt agtaagtctg gctgtaaacg
    17641 actttatcgc ccgccagcgc ggtaatgcgc ataccgtttt catgcagaga aaggttgtct
    17701 gcatggaagt tcatgcactg atcaaccggg aactccactt catgctgacc gtttgccagc
    17761 atcaggcgac catgagtatt cacatcctga ataaaaccag ggatggaatc gatatccacg
    17821 gtatccggca ggttacccgc caggcccata ataatggcga tatcagtgtg gtggccttta
    17881 ccggtcagag agagcgagcc gtacacgtca accaccacgc gggtcacgtc tttaagcaga
    17941 ttacgggcaa tcagatcgtc ggtaaattgt ttacccgctt tcattggtcc aacggtatga
    18001 gaactggaag ggccaatgcc gattttgaaa atatcgaata cgctaatcat aggaaataca
    18061 tcgcgttaaa acggaggaag cgccgcccga aagcggcgcg aaaggactta gctgaacaga
    18121 gagtagaaga ttgcggagat tgcaatcaga cccatcacga caacgaatac gttgctgatg
    18181 tgaccgctgt acttacgcat tgccggtact ttctgaattg cgtacatcgg catcaggaac
    18241 aggatcatcg cgatgattgg gccgcccagg gtttcaatca tacccaggat gctcgggttc
    18301 agggtggcaa caatccaggt cgttaccagc atgaacagcg cagtgatacg gttcagcttg
    18361 ttgatttcga tagacttacc tttaccacgc agagatttaa tcaccatacc gttgaagcct
    18421 tcacgtgcgc ccaggtagtg gccgaggaag gatttggtga tagcgataat cgcgataatc
    18481 ggagccatcc acgcgataac cggtgcgtta aagtggttag ccaggtaaga cagaatcgag
    18541 atgttctgct ctttagccgc agccaggtct gccggagtca ggctcagtac gcagctgaag
    18601 acgaagaaca ttacggtcag caccatcatg atgtgtgcga atgcaaggat cttcgagcat
    18661 ttctgttctg ccatatcgcc gtactcttca cgcttcgcaa cggcgaaaga agagatgatc
    18721 ggagagtggt tgaacgagaa caccattacc ggaattgcca gccacagggt catccacaga
    18781 ccgttcccgg ttgcagatgc agtgtccaga gacagcgttt ccagtgctgc gccgttccac
    18841 tgcgggatca ggtacagagc cagcagcatc agtacgccaa caaacgggaa taccagaata
    18901 ctcatcgctt taacgatcat ctgctcacca aagcgaacga tggtcatcat acccacgatc
    18961 aggatcagcg acagaatcgc acgcggcggt ggcgtcatac ccagctggtg agacatgaag
    19021 ctttcaactg tattggtgat tgccacgcta taaaccagca ggatcgggta gatagcgaag
    19081 aagtagagca gggtaatcag tttacctgcg ccaataccaa agtgttcttc tacaacctcg
    19141 gtgatgtctt cgcccgggtt tttaccagac agtacgaagc gagtcaggcc gcggtgagca
    19201 aaaaacgtca tcgggaacgc aaggatagcc atgatgatca gcgggatcat accgccaaca
    19261 ccggcgttga ttggcaggaa cagcacgccc gcgccgattg ccgtgccgta aaggcccagc
    19321 atccacatgg tgtctgtctt gcgccaggca ctacgagagt ctttcgacgc aatcgtgctg
    19381 gtttgagtcg tttccatcta tttctcctgg aggaatgcaa ataattcagc ttttagccag
    19441 ttcagcccgg gaaggtgcct gaccgtaaaa atgaaatctg tctatcggcg atggcttaat
    19501 catttaccgc cgtaataatt tgagggcgga aagatacaca caagttatgt atctatcagt
    19561 gatcttgatc tcaaatacaa taatctactt ggaagataga ttatcccaac gctttactct
    19621 gtaaatcaaa agtaaaagag aatttaaggg caatatttgc ccattaaacg acatctgact
    19681 tcttccgggg cgcgcaatat atgtaggttg aactgaaaaa atcaatactt ttagttaatc
    19741 atggcgataa tttctttttc atagcgataa aatacggttt atgaaaatag ggaaacgttt
    19801 gcgttgcaac ataaattgta tgacatatta actgtgatga tatttgtcgc gtgagggtgg
    19861 taagaaacat tcatataaca aatgaaatga gttgatgagt aagtgaccaa aaacgagaaa
    19921 acccggcaac aaacgtcacc gggggagcgg agattacgtg cagatttcgt agcaagggat
    19981 gtaggctgag cctggcaact tcatacgatg ctgggcaaca aaaccctgta gcaggtcgtc
    20041 catacgacgc ataatctctt tatcgccgtt gattttgtaa ggaccaaact cttcaatggc
    20101 gcgaataccg acttctttta cgttacccgc cacaataccg gagaacgcac ggcgcaggtc
    20161 ggcagccagc acttcaacag gttgatccgg gtaaagcttc agattagcca tattctcgtg
    20221 agacggctca aacggcattt gcaaatctgg tgcaatgcgc attgaccagt taaagctgta
    20281 agcgtcacca gtgtcgcggc gattttcttt caccagcggc atcgattttt tcatctgacg
    20341 agcgacttca gcggcgtcat caatgatgat gcggtaatgg cggcgcgcgt tttcgcccag
    20401 cgtatgtacg acaaactcgt ccagtacgcg gaagtagtcg gcgctctctt tcgggccggt
    20461 gaggatcaat ggtaaaacct gatctttgtt ggccgggttc attaaaattc ccagcaaata
    20521 cagcaactct tctgccgtac ccacaccgcc agggaagata atgatgccgt gagcgatacg
    20581 gacaaacgct tccagacgtt tttcgatatc cggcatgatg atcaattcgt tgaccagcgg
    20641 gttaggcggt tcagcggcga taatcgacgg ctctgtcata ccaataaaac gactgtcttt
    20701 gtaacgctgc tgcgcgtgtc cgaccgcagc acctttcatc ggcgcttcca tcgctcccgg
    20761 accacagccg gtgcagatat tcagctcacg caggcccagc tggtttccga cgcgacgggc
    20821 atacaaatac tcattttcgt taattgagtg accgccccag cagaccacca tatttggcgc
    20881 ttcacccaca tgcagcgcgc gagcgttacg caagatggaa aagaccaggt tagtgatgtg
    20941 gacggagttg tcgagattca ggttgggaaa acgaacggtg ttatggattt gcccgtaaac
    21001 gaagagaatg tcacgcagga ccgcgaacaa gttggcctgc aaagcgcgaa taattcgccc
    21061 atcgacaaaa gcctcttccg ggggattaat cagttccagc tttacgccgc gttcacggcg
    21121 caagacgtta atatcgaaat tttcaaaacg agacagcaat tctttgctgt tatcggtcaa
    21181 actaccggag ttcagtacgg caagtgaaca gttgcgaaac agttgataga ggtcgctgct
    21241 ggcggtgcgt ttaagcatat ccacttccag ctgcgacaac atatccatgg agccaagcgg
    21301 gctaatatgt gtaatcaaga aaaactcctt atgggacgaa tatcgtcatt ccctttgatt
    21361 acaatagccc tgcctgatga cctttcacaa ccttctgcgt gaatccagca cgcaaaattg
    21421 agaaaaaatt tattgccgaa ccagtcttgt ggtcgatggg acaaaatcgc tattactgcg
    21481 ccacgggtta atgtccagac cgccacgacg ggtataacgt gcgtaaacgc tcaatttttc
    21541 tggctggcag aagcgtaaca ggtcattaaa gatgcgttcc acgcactgtt cgtggaactc
    21601 gttgtgatga cggaatgaga ccaggtaacg cagcagtttt tctctgtcaa tttggcgtcc
    21661 acgatactga atttggatcg aaccccaatc tggttgatgg gtgatcaggc agtttgattt
    21721 cagcaggtgg ctgacaagcg tctcttccac tactttttca ccgctggtgg cattctccag
    21781 atagtcagta gtgaattcat agttatcgat agtgatatcc tggtcatcaa tgcaggtgcc
    21841 attgaaatga cctatcggct ggccttccag ttcatcaaga cgatataacg ccacgctaac
    21901 cttaccctgg gcgcaagtgc ttaagtcgcg ctccagcgtc tggcgcacct catcccagtt
    21961 attaaaacgc gtctggttaa aactgttgag atagagttta aaactcttcg actcaatcag
    22021 atttacgctg gtgtaatcaa gttcaacatg accgacagcg acctgcggca aacctttcgc
    22081 attcagccag gaaagttcat acagcgtcca gatatccgta ccgtgaaaag gcaggttatc
    22141 cgctttcaga cccagcgggt cgcgattcag gctgcgtgga acgccttgca gtaggctggc
    22201 gtcataggta tcccggtaat cggttgattt tccaagagtc aggcccgcaa gtgcctgatg
    22261 gtttgcataa gaagacatgt ttcaccgtca taaaccagat aaactaaacg acaagtgtat
    22321 ctggtttaag tgaagagaga aattagtgga cgatttgacc gcacaagccc tgaaagattt
    22381 tactgcacgc tactgcgatg cgtggcatga agagcataaa agctggccgt taagtgagga
    22441 actgtacggt gttccttcac cgtgcattat ttcaactacc gaagatgccg tatactggca
    22501 accccagccg tttaccgggg aacaaaatgt aaacgcggtt gaacgcgctt ttgatattgt
    22561 gatacaaccc acaattcata ccttttatac gactcagttt gccggggata tgcacgcgca
    22621 gtttggcgat atcaaactga cattgctgca aacctggagt gaagacgact tccgtcgggt
    22681 gcaggaaaat ctgattggtc atctggtgac tcagaaaagg ctaaaactgc cgcccacgct
    22741 atttatcgcg acgctggaag aagagttaga ggtcatctcg gtgtgtaatc tctccggtga
    22801 agtgtgcaaa gagacgctgg gaacacgtaa acggacgcat ttagcctcaa atcttgcgga
    22861 attccttaat caacttaagc ctcttctgta atccaaatac cccatctggt tgtgagagat
    22921 ctcttacaga ctctgtagga gatcgccagg aaataagcga atacttaaaa agataagaat
    22981 cgttattttc atttaaaatc aaaatgttga ttgttaattc ttaactttca tatgaaattt
    23041 tccttaaggc attgtctgta agcgccttgt aagacttcgc gaaaaagacg attctatctt
    23101 cgtcgacagg gagtcagaca acgaagtgaa catcaggatg atgacacttc tgcaggacac
    23161 accaggatgg tgtttcaggg aaaggcttct ggatgaagcg aagaggatga cgcaggacgc
    23221 gttaaaggac acctccagga tggagaatga gaaccggtca ggatgattcg gtgggtcagg
    23281 aaggccaggg acacttcagg atgaagtatc acatcggggt ggtgtgagca ggaagcaata
    23341 gttcaggatg aacgattggc cgcaaggcca gaggaaaagt tgtcaaggat gagcagggag
    23401 caacaaaagt agctggaatg ctgcgaaacg aaccgggagc gctgtgaata cagtgctccc
    23461 tttttttatt cctgctatcc ttcgcggcag tttttcttat tgaggttgct ttatgaccac
    23521 tcatgaccgc gttcgtctcc agttgcaggc gcttgaagcg ttactgcgtg aacatcagca
    23581 ctggcgaaac gatgaacccc agccgcatca atttaatagt acccaaccgt tctttatgga
    23641 caccatggaa ccactggagt ggttgcagtg ggtgctgatc ccgcgaatgc acgatttgtt
    23701 agataacaaa cagccgttac cgggcgcttt tgccgttgca ccctattatg aaatggcgct
    23761 ggcgacggac catccgcaac gcgcgcttat tctggctgag ctggaaaaac tggatgctct
    23821 ttttgcggat gatgcgagct aatgctggaa atactctatc aggatgaatg gctggttgcg
    23881 gtaaataaac cctccggctg gctggttcac cgcagctggc tggatcgcga cgagaaagta
    23941 gtggtcatgc aaaccgtgcg tgatcagatt ggccagcacg tttttaccgc tcatcgtctg
    24001 gaccgaccca cttctggtgt gttgttgatg ggattatcca gcgaggccgg acggctgctg
    24061 gcacaacagt ttgaacagca ccaaatccag aaacgttacc atgcgattgt gcgcggctgg
    24121 ttgatggaag aagcagttct ggattatcca ctggtggaag aactggacaa aatcgctgat
    24181 aaatttgccc gcgaagataa aggctcgcag ccagcagtga cgcattatcg cggtctggcg
    24241 accgtagaaa tgccggtagc gaccggacgt tacccgacca cgcgctacgg cctggtggaa
    24301 ctggagccga aaaccggacg caaacatcag cttcgccgac atcttgccca tttgcgtcat
    24361 ccgattattg gcgatagcaa acatggcgat ttacgccaga atcgcagcgg tgctgagcat
    24421 tttggcctcc agcggttaat gctacatgcc agtcagttgt cattgacgca tccttttact
    24481 ggcgagccgc tgactattca cgcgggcctg gacgacacct ggatgcaggc gttatcacaa
    24541 tttggctggc gcggtctgct tcctgaaaat gaaagggttg agttcagtgc gccatcgggt
    24601 caggatggag agataagttc ctaatccagg gagaaaacgg tatggcggaa attggtattt
    24661 ttgtcggcac catgtacgga aattcgctgt tagtggcgga agaagcagaa gcaattctga
    24721 ccgcacaggg ccacaaagca acggtatttg aagatcctga attaagcgac tggctgccct
    24781 atcaggataa gtatgttctg gtggttacgt ccacgaccgg gcagggcgac cttcctgata
    24841 gcattgtgcc gctctttcag ggaatcaaag atagtctggg cttccagccg aatctgcgtt
    24901 atggcgtgat tgcgctcggc gacagcagtt atgtaaattt ctgcaatggc ggcaaacagt
    24961 tcgatgcctt gttgcaggaa cagagcgctc agcgggttgg cgaaatgctg ttgattgacg
    25021 ccagtgagaa cccggaaccg gaaacggaat caaatccgtg ggtcgaacag tggggcacgc
    25081 tgttgtcctg atatgttcag cgagcggtaa atgtcgtttt agcggtgctg aatcgaatat
    25141 tttcaggcaa atgccagtaa aaactgcttc atagcgcgga tttttactgg cgtttgcctg
    25201 gagtcaagcg atccatttca tactcttctt tatttcttcg ttttaaccct tcctttcttg
    25261 ttcttgtttt catttccgtg aagtggattc caccgtccag ggctaatgcc aaaatcgggc
    25321 ctcattgaac gcattaatgt tgtgttgttg cacggtgagc cgctatggcg cgctttttat
    25381 actgctattg ccagatataa acacgcgccg tattcggcga acgacctata aaaacggcaa
    25441 aaaacaccct acgtcacctc tgatttcctg gctatgtcgc agtccagagt gagcgtggct
    25501 aacgcgaatt ttcaggagtg caacaatgag ttctttaagt caggctgcga gcagtgtgga
    25561 aaaacgcacg aatgctcgtt actggatagt ggtgatgttg tttatcgtca catccttcaa
    25621 ctacggcgac cgcgctacgc tttctattgc cggttcggaa atggccaaag atatcggcct
    25681 tgatcccgtg ggaatgggct atgtgttctc tgccttctca tgggcttatg ttatcgggca
    25741 gatccctggt ggttggttgc tggatcgttt tggttcaaaa cgcgtctact tctggtcgat
    25801 ctttatctgg tcgatgttta ccttgctgca aggcttcgtc gatatcttta gtggattcgg
    25861 cattatcgtt gccctgttta ctctgcgctt cctggtcggg cttgctgaag cgccatcttt
    25921 ccccggcaac agtcgcattg ttgcggcctg gtttccggcg caggaaaggg gaacggcggt
    25981 gtcgattttt aactccgctc aatacttcgc aacggtgatc ttcgcgccga ttatgggctg
    26041 gctgacgcat gaagtgggct ggtcacacgt cttcttcttt atgggcggtc tggggattgt
    26101 catcagcttt atctggttga aagtcatcca cgagccaaat caacatccgg gggtaaatca
    26161 gaaagagctg gagtacatcg ccgcgggtgg cgcgctgatc aatatggatc agcaaaacac
    26221 caaagttaaa gtgccgttca gcgtgaagtg ggggcagatc aaacaactgc tcgggtcacg
    26281 gatgatgatc ggcgtttata tcggtcagta ctgtatcaac gccctgactt actttttcat
    26341 tacctggttt ccggtttatc tggtgcaggc gcgtgggatg tcgattctga aagcgggctt
    26401 tgtggcttcc gttccggcgg tttgcggttt tatcggcggt gtgctgggtg ggattatttc
    26461 cgactggctg atgcgccgca cgggatcgct gaacattgcg cgtaaaacac cgatcgtaat
    26521 gggcatgttg ctgtcgatgg tgatggtgtt ctgcaactac gtcaacgttg agtggatgat
    26581 catcggcttt atggcgctgg ccttcttcgg taagggcatc ggggcgctgg gttgggcagt
    26641 aatggcagat accgcgccaa aagagatcag cggtctttcc ggtggcctgt tcaacatgtt
    26701 cggtaacatt tctggcatcg tcacgccaat cgcaattggt tatatcgttg gcacgactgg
    26761 ctcctttaat ggggcgctga tttatgttgg tgttcatgcc ttaatcgcgg tactgagcta
    26821 cctggtgctg gtgggcgata tcaagcgtat cgagctgaaa cctgtcgcgg ggcaataaga
    26881 tgacgacaca atccagtcct gttattactg atatgaaagt cattccggtc gccgggcacg
    26941 atagcatgtt gcttaatatt ggtggggcac ataacgcata tttcacccgc aatattgtgg
    27001 tactcaccga taacgccggg cataccggca ttggtgaagc gccgggcgga gaggtgattt
    27061 atcaaacact ggtcgatgct attccgatgg ttctgggcca ggaagttgcg cgcctgaata
    27121 aagtggttca gcaggtgcat aaaggtaatc aggcagccga ttttgatacc ttcggcaaag
    27181 gtgcctggac ttttgaattg cgcgttaatg ccgtggcggc gctggaagcc gccttgcttg
    27241 acctgctagg taaggcgctg aatgttccgg tctgcgaact gttggggcca ggcaagcaac
    27301 gcgagactat taccgtcctc ggttatctgt tttatatcgg tgatcggacc aaaaccgatc
    27361 ttccttatct ggaaaatacg ccgggcaacc atgagtggta tcagttgcgc catcagaaag
    27421 cgatgaacag cgaagccgtt gtgcgtctgg cggaagcctc acaggatcgc tatggcttta
    27481 aagatttcaa acttaagggc ggggtgttac ctggcgagca agaaatcgac actgttcgtg
    27541 cattgaagaa acgcttccct gatgcgcgga ttaccgttga tcccaacggt gcctggctac
    27601 ttgatgaagc catttctcta tgcaaagggc tgaatgatgt tcttacctat gccgaagatc
    27661 catgcggcgc agaacagggt ttctccggtc gtgaagttat ggcggagttt cggcgggcga
    27721 ccggcttgcc cgtcgcgact aacatgatcg ccaccaactg gcgcgaaatg ggtcatgcgg
    27781 tgatgctcaa tgcggtagat attccacttg ccgatccgca cttctggacg ctttccggtg
    27841 cagtccgtgt ggcgcagctt tgcgacgact gggggctgac ctggggctgc cattctaata
    27901 accatttcga tatctctctg gcgatgttta cccatgtggg cgcggcggca ccgggtaatc
    27961 ctaccgctat cgatacccac tggatttggc aggagggcga ttgtcgcctg accaaaaatc
    28021 cgctggagat taaaaacgga aaaattgccg ttcctgatgc gcccggtctg ggcgtggaac
    28081 tggactggga acaggtacaa aaggcacatg aggcctataa acgtctgcct gtcggtgcgc
    28141 gtaacgacgc aggtccgatg cagtacctga tccccggctg gacctttgac cgtaaacgtc
    28201 ccgttttcgg ccgtcattga ttctgaaaaa ggacataaat atgagttctc aatttacgac
    28261 gcctgttgtt actgaaatgc aggtcatccc ggtggcgggt catgacagta tgctgatgaa
    28321 tctgagtggt gcacacgcac cgttctttac gcgtaatatt gtgattatca aagataattc
    28381 tggtcacact ggcgtagggg aaattcccgg cggcgagaaa atccgtaaaa cgctggaaga
    28441 tgcgattccg ctggtggtag gtaaaacgct gggtgaatac aaaaacgttc tgacgctggt
    28501 gcgtaatact tttgccgatc gtgatgctgg tgggcgcggt ttgcagacat ttgatttgcg
    28561 taccactatt catgtagtta ccgggataga agcggcaatg ctggatctgc tggggcagca
    28621 tctgggggta aacgtggcat ccctgctggg cgatggtcaa cagcgtagcg aagtcgaaat
    28681 gctcggttat ctgttcttcg tcggtgatcg caaagccaca ccgctgccgt atcaaagcca
    28741 gccggatgac tcatgcgact ggtatcgcct gcgtcatgaa gaagcgatga cgccggatgc
    28801 ggtggtgcgc ctggcggaag cggcgtatga aaaatatggc ttcaacgatt tcaaactgaa
    28861 aggcggtgta ctggccgggg aagaagaggc cgagtctatt gtggcactgg cgcaacgctt
    28921 cccgcaggcg cgtattacgc tcgatcctaa cggtgcctgg tcgctgaacg aagcgattaa
    28981 aattggtaaa tacctgaaag ggtcgctggc ttatgcagaa gatccgtgtg gtgcggagca
    29041 aggtttctcc gggcgtgaag tgatggcaga gttccgtcgc gcaactggcc tgccgaccgc
    29101 aaccaatatg atcgccaccg actggcggca gatgggccat acgctctccc tgcaatccgt
    29161 tgatatcccg ctggcggatc cgcatttctg gacgatgcaa ggttcggtac gtgtggcgca
    29221 aatgtgccat gaatttggcc tgacctgggg ttcacactca aacaaccact tcgatatttc
    29281 cctggcgatg tttacccatg ttgccgccgc tgcaccgggt aaaattactg ctattgatac
    29341 gcactggatc tggcaggaag gtaatcagcg cctgaccaaa gaaccgtttg agatcaaagg
    29401 cgggctggta caggtgccag aaaaaccggg gctgggtgta gaaatcgata tggatcaagt
    29461 gatgaaagcc catgagctgt atcagaaaca cgggcttggc gcgcgtgacg atgcgatggg
    29521 aatgcagtat ctgattcctg gctggacgtt cgataacaag cgcccgtgca tggtgcgtta
    29581 agacagaaaa ccaaaaccgg ctctatctgg agccggcttg agactgatgc taaacgcaaa
    29641 atagcctgtt gtgctatgta tcaggtctac atcatttttt aattcattga atttaattgg
    29701 ttttgtaggc cggataaggc gttaacgccg catccggcat aaacacaggc actttgtcac
    29761 caatctgaaa ccagcgtcat aaaaagccga ttgctactcg acaagacgtc cgttacccga
    29821 gaattttgct ggcttcgcgc gctacattat ccatctcgtc caacagttcc agcagctccg
    29881 gctccaaatc ttcttcttta gtaccgctac gtagctgttg ttcgatcagt tggcagagat
    29941 tcttcatacg cggcacaccg ctatagccgc aactgccatg cagtttatga atcaaatcaa
    30001 ccaggccttc cgggttttct ccaaccagct gttcctcaac tttgttgcga acttcaggca
    30061 ggaaatcgag taacatttgc agcatatcgc gcgctaaatc ggtttttcct gctgcctggc
    30121 gtagtgccag ttgccagtcg agggtcgcat tcgggttcac cacaatttcg ttgacttcgg
    30181 gcgtcacgac gcgagaggaa ataccgctgc caggcttgta gcgcaacaac aaattatgca
    30241 atcgctcttc ttcaatcggt ttcgccagat aatcgctcat ccctgcgcca agcagcttct
    30301 ctttttgccc ggccattgca tgcgccgtta ccgcgataac cggcgtttgt tgctgatggg
    30361 ggagctggtg gatgagctcg caggcccgaa tgccatccat gtcaggcatt tgaatatcca
    30421 ttaagatcaa atcgaacggc atctgtttcg cccgttcaac cgcctgatgc ccgctatcgc
    30481 aaagttccac atgttgcacc atatcttcca gcaatgcgcc gataagtttc aggttagcgg
    30541 ggttgtcatc aactgccatg actgtcattg ccagcttgct ttcatcggtt acaggcaaaa
    30601 gcgtgttttg tttgtgatga caaaattccg tcagggcagg caacaggcgc gtaggtgtta
    30661 atggtttcag cagacacgcg ccgataccat cttgcttgag tttttctgca ttgacttgtg
    30721 catggcaagg aagtgccagc atcaggaaat cggtcatcga taccgctttc gctaatcgct
    30781 catgttgcat tgttagcggc tcgcggaagg tcaccgcgat gcctaacaac atcatgtcgt
    30841 aatgcgcggg aggcagcgcg gagaacgttg ggctataaac cacttccagc ggcgtttcac
    30901 ttaaaatatc cagcgtgcat tgcgctgctg cggagtttgg ttcgacatag gccaggcgct
    30961 taccggcgag gcactgggtg gatggccctt cgataataat gttcgggttc agatcgagat
    31021 taatgtggaa ccagaaagtt gaaccgcgat tcggctggct atggaacgaa atatcgccgc
    31081 ccatttcatt aaccagtttt tgtgtaatca ccagccccag accggtgcca ccatgacggc
    31141 gggaaatact ggcatcagcc tgtcggaagg cctggaataa gcgcgattga tcgcgttcag
    31201 gaataccaat gccggtatcc cgaatctgca cttcaatctg cactttggta ttactcagcg
    31261 cacgtttttc taccagaata tcaatgttgc cattctcggt gaatttaatt gcattcccca
    31321 ccaggttagt gatgatttgc tgtaatcgca gtgggtcgcc gatcacgtta tcaggcacgt
    31381 cgcttttaat attgagcgtc agttccaacc ctttatcgtg agaagaatgt gccagcagag
    31441 taacgacttc atccagcgtg ctgcgtagtg ggaatggaat actttccaga atcagcttac
    31501 ctgcttccag tttcgagaag tcgagaacat cattaataat tgccagcaaa ttatttgccg
    31561 aacgttcaat cgtattcagg tgatcgcgct gcgttggtgt taattctgtt ttcagcgtca
    31621 ggcgggtaaa gccaataaca ccattcagtg gtgtacgcag ctcgtgtgac atatttgcca
    31681 gaaactcgga tttaatacgc gccgcttcct gggcgcgctt tttcgccaga tctaactcaa
    31741 cgttctgaat ttccatctgc tccagcgttt cacgcagatc ggacgtcgcc tggtcgatat
    31801 tgtgctgcat ctcttcgtga taagcagcca gcgacattgc catcgagttg ataccgtttt
    31861 tcagcatatc cagctcgccg agcataaatc cttccacccg gctgtcgagt tgcccgcgac
    31921 ggatgcggtc gacggtattc accatgttgc gaatcggacc ggttacatcg cgcattaagc
    31981 gccagccaaa aataagcgca ataccgatac aaaacagcat catcacgctg gaaataaaga
    32041 tctctttata ttgctgcaag cgaaccgatt taagatccag ctccagcgca atatatccca
    32101 acatattttg actatttttg gcatcgctac tgggcgattc gtcgggggag taactctcag
    32161 aaataatcgg cgtgcggagg atcataatat cgccgtcacg agtgacagtg agctggcgag
    32221 gaaacggcac gttgctgccg agctgcattg atgagggatc aagatgaaaa ttggaggtga
    32281 caaagagtcg gttattttca tcataaaccg aaatcgcgcg aacaatatcg gaatggcgac
    32341 gatgcagtac gcttattaac tgaccgatag attcgcgatt ttgcaggctc atgccatatt
    32401 cagtagaaac tgcaagcggc tcaataatgc tggcaccggc atcttccagt tgacgctgca
    32461 agtcgttata gcgatgcacg acgaaaaaga tactcagcaa taaaccaata aggacggtcg
    32521 gtgccaggat cagaatcatc atgcgtgcgc gcaggctgta gttggtcatg gagttccgtt
    32581 atgggacaat taaggtcaca ctgttaaatt gagaaagtct cgccaatggc gcaattctac
    32641 tctgcaaaac gacgcacgac gacgcgtcag atcataaccg tttcagtcaa cgacctcgac
    32701 tcttttggtc agggcgtggc gcgacataac ggcaaaacgt tatttatccc cggattattg
    32761 ccgcaggaaa acgcggaagt tgctgttact gaagataaaa aacagtatgc ccgcgctaaa
    32821 gtcgtacgcc ggttaagcga tagcccggaa cgcgaaacac cacgctgtcc tcattttggc
    32881 gtatgcggcg gctgtcagca acaacacgcc agcgtggatt tacagcagcg aagcaaaagt
    32941 gcggcactcg cccgattaat gaaacacgat gtctctgaag tgatcgccga tgttccctgg
    33001 ggctatcgcc gccgcgcgcg tttaagtctg aactacttac cgaaaacaca gcaacttcag
    33061 atggggtttc gcaaagcggg ctccagtgac attgtcgacg ttaaacaatg ccccatttta
    33121 gtgccccaac ttgaagcatt gctgcccaaa gtcagggcat gcctgggcag cttacaagtt
    33181 atgcgccatc ttggtcatgt tgaactggta caggcaacca gcggcacgct gatgattttg
    33241 cgccataccg caccgctaag ttcggcagat cgcgaaaaac tggaacgctt ttcgcattct
    33301 gaaggcctgg atctgtatct cgcccccgat agtgagatac tcgaaaccgt ctctggtgag
    33361 atgccctggt atgactcaaa cgggttgcgc ttaactttta gcccgcgcga ttttattcag
    33421 gtcaatgcgg gtgtgaacca aaaaatggta gcgcgtgcgt tggaatggct ggatgtgcaa
    33481 cctgaagatc gcgtactgga tctgttctgc ggtatgggca actttacact gccattggcg
    33541 aaacaagcag ccagtgtggt cggtgtagaa ggtgttccgg cgctggtgga aaaaggccag
    33601 cagaatgcgc gtcttaatgg tttacagaat gtgacgtttt atcacgaaaa tcttgaagaa
    33661 gatgtcacaa agcagccgtg ggcgaaaaac ggcttcgata aagtgttgct ggacccggcg
    33721 cgagcaggtg ccgcaggtgt tatgcagcaa attataaaac tggaacctat tcgtatagtt
    33781 tatgtatcct gtaaccctgc aacgctggct cgggatagcg aagcgttatt aaaagcagga
    33841 tataccattg cgcgactggc gatgctggat atgttcccac acacgggaca tctggaatcg
    33901 atggtacttt tctcgcgcgt taaatagtta cgatttgccg atttcggcag gtctggtccc
    33961 taaaggagag gacaatggtt gcggtaagaa gtgcacatat caataaggct ggtgaatttg
    34021 atccggaaaa atggatcgca agtctgggta ttaccagcca gaagtcgtgt gagtgcttag
    34081 ccgaaacctg ggcgtattgt ctgcaacaga cgcaggggca tccggatgcc agtctgttat
    34141 tgtggcgtgg tgttgagatg gtggagatcc tctcgacatt aagtatggac attgacacgc
    34201 tgcgggcggc gctgctgttc cctctggctg atgccaacgt agtcagcgaa gatgtgctgc
    34261 gtgagagcgt cggtaagtcg gtcgttaacc ttattcacgg cgtgcgtgat atggcggcga
    34321 tccgccagct gaaagcgacg cacactgatt ctgtttcctc cgaacaggtc gataacgttc
    34381 gccggatgtt attggcgatg gtcgatgatt ttcgctgcgt ggtcatcaaa ctggcggagc
    34441 gtattgctca tctgcgcgaa gtaaaagatg cgccggaaga tgaacgcgta ctggcggcaa
    34501 aagagtgcac caatatctac gcgccgttgg cgaaccgtct tgggattggg caactgaaat
    34561 gggagctgga agattactgc ttccgttatc tccacccgac cgaatacaaa cgcatcgcaa
    34621 aactgctgca tgaacgccgt ctcgaccgcg aacactatat cgaagagttt gtcggccatc
    34681 tgcgcgctga gatgaaagct gaaggcgtta aagctgaagt gtatggtcgt ccgaaacaca
    34741 tctacagtat ctggcgcaaa atgcagaaaa agaacctcgc cttcgatgag ctgtttgatg
    34801 tgcgtgcggt acgtattgtc gccgagcgtt tacaggattg ttatgccgca ctggggatag
    34861 tgcacactca ctatcgccac ctgccggatg agtttgacga ttatgtcgct aacccgaaac
    34921 caaacggtta tcagtctatt cataccgtgg ttctggggcc aggtggcaaa accgttgaga
    34981 tccaaatccg caccaaacag atgcatgaag atgcagagtt gggtgttgct gcgcactgga
    35041 aatataaaga gggcgcggca gctggcggcg cacgttcggg acatgaagac cggattgcct
    35101 ggctgcgtaa actgattgcg tggcaggaag agatggctga ttccggcgaa atgctcgacg
    35161 aagtacgcag ccaggtcttt gacgaccggg tgtatgtctt tacgccgaaa ggtgatgtcg
    35221 ttgatttgcc tgcgggatca acgccgctgg acttcgctta ccacatccac agtgatgtcg
    35281 gacaccgctg catcggggca aaaattggcg ggcgcattgt gccgttcacc taccagctgc
    35341 agatgggcga ccagattgaa attatcaccc agaaacagcc gaaccccagc cgtgactggt
    35401 taaacccaaa cctcggttac gtcacaacca gccgtgggcg ttcgaaaatt cacgcctggt
    35461 tccgtaaaca ggaccgtgac aaaaacattc tggctgggcg gcaaatcctt gacgacgagc
    35521 tggaacatct ggggatcagc ctgaaagaag cagaaaaaca tctgctgccg cgttacaact
    35581 ttaatgatgt cgacgagttg ctggcggcga ttggtggcgg ggatatccgt ctcaatcaga
    35641 tggtgaactt cctgcaatcg caatttaata agccgagtgc cgaagagcag gacgccgccg
    35701 cgctgaagca acttcagcaa aaaagctaca cgccgcaaaa ccgcagtaaa gataacggtc
    35761 gcgtggtggt cgaaggtgtt ggcaacctga tgcaccacat cgcgcgctgc tgccagccga
    35821 ttcctggaga tgagattgtc ggcttcatta cccaggggcg cggtatttca gtacaccgcg
    35881 ccgattgcga acaactggcg gaactgcgct cccatgcgcc agaacgcatt gttgacgcgg
    35941 tatggggtga gagctactcc gccggatatt cgctggtggt ccgtgtggtg gctaatgatc
    36001 gtagtgggtt gttacgtgat atcacgacca ttctcgccaa cgagaaggtg aacgtgcttg
    36061 gcgttgccag ccgtagcgac accaaacagc aactggcgac catcgacatg accattgaga
    36121 tttacaacct gcaagtgctg gggcgcgtgc tgggtaaact caaccaggtg ccggatgtta
    36181 tcgacgcgcg tcggttgcac gggagttagg ccgaaatttg ctcgtatcta caatgtagat
    36241 tgatatatac tgtatctaca tatgatagcg gtttgaggaa agggttatga tccacagtag
    36301 cgtaaagcgt tggggaaatt caccggcggt gcggatcccg gctacgttaa tgcaggcgct
    36361 caatctgaat attgatgatg aagtgaagat tgacctggtg gatggcaaat taattattga
    36421 gccagtgcgt aaagagcccg tatttacgct tgctgaactg gtcaacgaca tcacgccgga
    36481 aaacctccac gagaatatcg actggggaga gccgaaagat aaggaagtct ggtaatggta
    36541 agccgatacg tacccgatat gggcgatctg atttgggttg attttgaccc gacaaaaggt
    36601 agcgagcaag ctggacatcg tccagctgtt gtcctgagtc ctttcatgta caacaacaaa
    36661 acaggtatgt gtctgtgtgt tccttataca acgcaatcaa aaggatatcc gttcgaagtt
    36721 gttttatccg gtcaggaacg tgatggcgta gcgttagctg atcaggtaaa aagtatcgcc
    36781 tggcgggcaa gaggagcaac gaagaaagga acagttgccc cagaggaatt acaactcatt
    36841 aaagccaaaa ttaacgtact gattgggtag tgttactaac tcacttctat tctggtcaca
    36901 ggtttccacc tgacagaccc gcaattttca ggacaattca atgaatcaaa tcgaccgttt
    36961 gctcactatt atgcagcgcc tgcgcgatcc ggaaaacggc tgcccgtggg ataaagagca
    37021 gacatttgcc accattgcgc cttacaccct tgaagaaacc tacgaagtgc tggacgccat
    37081 cgcccgtgaa gattttgacg atcttcgcgg tgaactgggc gatctgctat tccaggtggt
    37141 gttttacgcg caaatggctc aggaagaagg gcgctttgac tttaatgata tttgcgctgc
    37201 tattagcgat aaattagagc gtcgccatcc gcatgttttt gctgatagtt ctgccgaaaa
    37261 cagtagtgaa gtgcttgccc gttgggagca aatcaaaacc gaagagcgcg cgcagaaagc
    37321 gcagcattcg gcgctggacg atattcctcg tagtttaccg gctttaatgc gtgcgcaaaa
    37381 aatccagaaa cgttgcgcca acgttggctt cgattggacg acgcttggtc cggtagtcga
    37441 taaagtctac gaagagatcg acgaggtgat gtacgaagcg cggcaggctg ttgtcgacca
    37501 ggctaaactg gaggaggaaa tgggggacct gctgtttgcc acggtcaatc tggctcgtca
    37561 tttagggaca aaagcggaaa tcgcattgca aaaagcgaac gaaaaatttg agcgtcgttt
    37621 tcgcgaagtg gagcgtattg ttgccgcgcg tggactggaa atgacaggtg ttgacctcga
    37681 aacaatggaa gaagtctggc aacaggtaaa acggcaggaa attgatctct aagggaatta
    37741 cgcggtcaag cgccatttgt gtcatttttt aaatgacaag cgcttgattt gcgtcaaaaa
    37801 catttacccc aaaggggcta ttttctcact cctgatttca atagtgcgct ggcgaagagg
    37861 agggataatg aaagtttgtg gcacaggtca tgttcgggta tactgctttc ccgtcctggt
    37921 tattccatcg tcttttcaac ctaacttctc aggttcagca tgacaacgaa ctatattttt
    37981 gtgaccggcg gggtcgtatc ctctctgggt aaaggcattg ccgcagcctc cctcgcagcc
    38041 attcttgaag cccgtggcct caatgtgacc atcatgaaac tggatccgta catcaacgtc
    38101 gatccaggta ctatgagccc aatccaacac ggggaagtgt tcgttactga agacggcgct
    38161 gaaaccgacc tggacctggg gcactacgag cgtttcattc gtaccaaaat gagccgccgc
    38221 aacaacttca ccacgggtcg tatctactct gacgttctgc gtaaagaacg ccgcggtgac
    38281 tacctcggcg caaccgtgca ggttattccg cacatcacta acgcaatcaa agagcgcgtg
    38341 ctggaaggtg gcgaaggtca tgacgtagta ctggtagaaa tcggcggtac agtaggtgat
    38401 atcgaatcct tgccgttcct cgaagcgatt cgccagatgg ctgttgaaat tggccgtgag
    38461 cacactctgt ttatgcacct gacgctggtg ccgtacatgg cagcgtctgg tgaagtcaaa
    38521 accaaaccga ctcagcactc tgtaaaagag ctgctctcca tcggtatcca gcctgacatc
    38581 ctgatttgtc gttcagatcg cgctgttccg gcgaacgaac gtgcgaagat tgcattgttc
    38641 tgtaatgttc cggaaaaagc ggttatttct ctgaaagacg tcgattccat ctataaaatt
    38701 ccgggcctgt tgaaatctca ggggctggac gattatattt gtaaacgatt cagcttaaac
    38761 tgcccggaag cgaatctgtc cgaatgggaa caggttatct tcgaagaagc gaatccggta
    38821 agtgaagtca ccatcggtat ggtcggcaag tacattgaac tgccggatgc ttataaatca
    38881 gtgatcgaag cactgaaaca cggtgggctg aagaatcgtg tcagcgtcaa catcaaactg
    38941 atcgattcac aagatgttga aacgcgcggc gttgaaatcc ttaaaggtct ggacgcaatc
    39001 ctcgtacctg gcggttttgg ctatcgtggc gtagaaggca tgattacgac cgcgcgtttt
    39061 gcgcgtgaga acaatattcc ttatctgggc atttgcctgg gtatgcaggt ggcgttaatt
    39121 gattacgctc gccatgttgc caacatggag aacgccaact ctacggaatt tgtgccagaa
    39181 tgtaagtacc cggttgtggc gctgattacc gagtggcgcg atgaaaacgg caacgttgaa
    39241 gttcgtagcg agaagagcga tctcggcgga accatgcgtc tcggcgcaca gcagtgccag
    39301 ttggttgacg atagcctggt tcgccagctg tacaatgcgc cgacaattgt tgagcgtcat
    39361 cgtcaccgtt acgaagtcaa caacatgctg ttgaaacaga ttgaagatgc aggtctgcgc
    39421 gttgcgggcc gttccgggga tgatcagttg gtcgagatca tcgaagttcc gaatcacccg
    39481 tggttcgtgg cttgccagtt ccatccggag tttacttcta ctccacgtga tggtcacccg
    39541 ctgtttgcag gctttgtgaa agccgccagc gagttccaga aacgtcaggc gaagtaagta
    39601 aaaaagttag aacggcaacg cgtaccctgg gtacgcgttg tttgtctgga gtttcagttt
    39661 aactagtgac ttgaggaaaa cctaatgtcc aaaatcgtaa aaatcatcgg tcgtgaaatc
    39721 atcgactccc gtggtaaccc gactgttgaa gccgaagtac atctggaggg tggtttcgtc
    39781 ggtatggcag ctgctccgtc aggtgcttct actggttccc gtgaagctct ggaactgcgc
    39841 gatggcgaca aatcccgttt cctgggtaaa ggcgtaacca aagctgttgc tgcggtaaac
    39901 ggcccgatcg ctcaggcgct gattggcaaa gatgctaaag atcaggctgg cattgacaag
    39961 atcatgatcg acctggacgg caccgaaaac aaatccaaat tcggcgcgaa cgcaatcctg
    40021 gctgtatctc tggctaacgc caaagctgct gcagctgcta aagggatgcc gctgtacgag
    40081 cacatcgctg aactgaacgg tactccgggc aaatactcta tgccggttcc gatgatgaac
    40141 atcatcaacg gtggtgagca cgctgacaac aacgttgata tccaggaatt catgattcag
    40201 ccggttggcg cgaaaactgt gaaagaagcc atccgcatgg gttctgaagt tttccatcac
    40261 ctggcaaaag ttctgaaagc gaaaggcatg aacactgctg ttggtgacga aggtggctat
    40321 gcgccgaacc tgggttccaa cgctgaagct ctggctgtta tcgctgaagc tgttaaagct
    40381 gctggttatg aactgggcaa agacatcact ctggcgatgg actgcgcagc ttctgaattc
    40441 tacaaagacg gtaaatacgt tctggctggc gaaggcaaca aagcgttcac ctctgaagaa
    40501 ttcactcact tcctggaaga actgaccaaa cagtacccga tcgtttctat cgaagacggt
    40561 ctggacgaat ctgactggga cggtttcgca taccagacca aagttctggg cgacaaaatc
    40621 cagctggttg gtgacgacct gttcgtaacc aacaccaaga tcctgaaaga aggtatcgaa
    40681 aaaggtatcg ctaactccat cctgatcaaa ttcaaccaga tcggttctct gaccgaaact
    40741 ctggctgcaa tcaagatggc gaaagatgct ggctacactg cagttatctc tcaccgttct
    40801 ggcgaaactg aagacgctac catcgctgac ctggctgttg gtactgctgc aggccagatc
    40861 aaaactggtt ctatgagccg ttctgaccgc gttgctaaat acaaccagct gattcgtatc
    40921 gaagaagctc tgggcgaaaa agcaccgtac aacggtcgta aagagatcaa aggccaggca
    40981 taagactgac tttatctgat ttaaaaatgc cagcctccgg gctggcattt tttatggttg
    41041 agttaccagc ggccggatgc gccgccacct ccagaagaac cgccaccgcc gctaaatccg
    41101 ccgccacttg agcctccacc ggaaccgctg ttgtctgaat gataactttt acctgatgct
    41161 cttttctgaa gtacacataa acaggtaaag accataaata tggtgaaagt aaaaaagaag
    41221 gaaaatacag caatggaaaa aattttatcg gagaacagga ataaatctaa aagatagatt
    41281 gctgaaatat agactccact tttacatgcg cgacaaaaat tactgccttg atgaaaaaac
    41341 cagaaaggga agaacatcac tgcaaatacc caaaaaatag caaagtaata atgatcactg
    41401 gaagacgctg attcactttc tgaaggatta gtcggatatt ggtgttgtga agtgagttgg
    41461 ttattcaaag cgtttatagc tagctctaat ccctgagcaa atttttgttg tttaaatgcg
    41521 ggtatcatgt tgctacggat gatatctcta gccagagcat cggttacctt ttcttccagc
    41581 ccataaccta cctggatgcg gacagtacga tctgaccagg caacaatgat cagtatccca
    41641 tcattacgtt tggcatctcc taaacgccaa ttgtcaaaaa ctcttgtagc atattgttca
    41701 attgtctcgt ctttggttgt gggaacaatt aatacagcaa tttgcacttg ggtattattg
    41761 aaaatagatt ctaacttgtg cgtcagttct ttcttttctt gtgagtttaa gctactcgta
    41821 agatccgtaa cttgttactg taattgtggg acaatagttg gttgggctgc aacaaaggaa
    41881 catacgaaag tgaacattag tatgaaatag cgcattataa atttctcatt aaatctggat
    41941 aaataaattg acggcggcat cggtaa
//
LOCUS       DAZUDJ010000041        40411 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.041, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000041 DAZUDJ010000000
VERSION     DAZUDJ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40411
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.041"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            93..536
                     /gene="cmtB"
                     /locus_tag="ACHY1N_002898"
     CDS             93..536
                     /gene="cmtB"
                     /locus_tag="ACHY1N_002898"
                     /EC_number="2.7.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IIA"
                     /protein_id="HFS4045183.1"
                     /translation="MRLSDYFPESSISVIHSAKDWQEAIDFSMVSLLDKNYISENYIQ
                     AIKDSTINNGPYYILAPGVAMPHARPECGALKTGMSLTLLEQGVYFPGNDEPIKLLIG
                     LSAADADSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISRG"
     gene            564..1952
                     /gene="cmtA"
                     /locus_tag="ACHY1N_002899"
     CDS             564..1952
                     /gene="cmtA"
                     /locus_tag="ACHY1N_002899"
                     /EC_number="2.7.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFS4045184.1"
                     /translation="MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWL
                     PNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIGTIGVIVGAEIPMFLGSM
                     IMGPLGGLVIKYVDKALEKRIPAGFEMVINNFSLGIAGMLLCLLGFEVIGPAVLIANT
                     FVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMV
                     ASNLGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIA
                     GGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLI
                     LKMEKTVETESEDEFAQSANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFR
                     KRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLD
                     TLFNQLTAEHKH"
     gene            1967..3244
                     /gene="yggP"
                     /locus_tag="ACHY1N_002900"
     CDS             1967..3244
                     /gene="yggP"
                     /locus_tag="ACHY1N_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HFS4045185.1"
                     /translation="MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWK
                     AALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSG
                     YSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
                     TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQV
                     QKLLPVDLAASKGIELVYVNTKGMSDPVQTLRALTGDVGFDDIFVYAAVPAVVEMADE
                     LLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQL
                     QPSFMVTHIGGLDAVPDTVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKE
                     LARLVEETHGIWNEQAEKYLLAQFGVDIGEAAQ"
     gene            3241..4206
                     /gene="glpX"
                     /locus_tag="ACHY1N_002901"
     CDS             3241..4206
                     /gene="glpX"
                     /locus_tag="ACHY1N_002901"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HFS4045186.1"
                     /translation="MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALN
                     DVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNALAV
                     MAFAPRDSLLHAPDTYMKKLVVNRLAAGAIDLSLPLADNLRNVAKALGKPLDKLRMVT
                     LDKPRLSAAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISAC
                     AVKALGGDMQAELIDFCQAKGDYTENRQIAEQERKRCKAMGVDVNRVYSLDELVRGND
                     ILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSLH"
     gene            4228..4737
                     /gene="fumE"
                     /locus_tag="ACHY1N_002902"
     CDS             4228..4737
                     /gene="fumE"
                     /locus_tag="ACHY1N_002902"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarase E"
                     /protein_id="HFS4045187.1"
                     /translation="MATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVD
                     NDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQYWHYLNEQD
                     ETPGFADDMTWDFISNVNSITCNATLYDALKAMKFADFAVWSEARFSGMVKTALTLAV
                     TTTLKELTP"
     gene            4734..5447
                     /locus_tag="ACHY1N_002903"
     CDS             4734..5447
                     /locus_tag="ACHY1N_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="HFS4045188.1"
                     /translation="MKIELTVNGLNVQAQYHDEEIERVHKPLLRMLAALQTVSPQRRT
                     VVFLCAPPGTGKSTLTTFWEYLAQQDPELPAIQTLPMDGFHHYNSWLDAHQLRPFKGA
                     PETFDVAKLAENLCQVVEGDCTWPQYDRQKHDPVEDALHVTAPLVIVEGNWLLLDDEK
                     WCQLAQFCDFSIFINAPATALRERLVGRKLAGGVSLADAEAFYDRTDGPNVRRVLEES
                     LPANLTLMMTATGEYRLVD"
     gene            complement(5419..6089)
                     /locus_tag="ACHY1N_002904"
                     /pseudo
     CDS             complement(5419..6089)
                     /locus_tag="ACHY1N_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708691.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(6083..6760)
                     /locus_tag="ACHY1N_002905"
     CDS             complement(6083..6760)
                     /locus_tag="ACHY1N_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4045189.1"
                     /translation="MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTL
                     AQLMAGWYPDFLPGEITGTGTLLGTPIGHLPLNEQSATIQLVQQSPYLQLSGCTFSVE
                     EEVAFGPENLCLAEAEIMARIDAALTLTECQPLRHRHPATLSGGETQRVVIACAIAMQ
                     PKLLILDEAFSRLTPQASEMLLQRLQHWAFERGSLIILFERHRTPFLNYCQQAWQLQN
                     GALQPLC"
     gene            complement(6748..7455)
                     /locus_tag="ACHY1N_002906"
     CDS             complement(6748..7455)
                     /locus_tag="ACHY1N_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HFS4045190.1"
                     /translation="MHPFTSLTLWALAACTTLILPAQTILPIYSAATFFCLIALKATR
                     RRAKYVVWLMFSLGAGLWLVHGGWLPEWLSGTPRSPERWSHAITLWLRILAIVSTSQL
                     WMQYVPVQCFIRALFASRLPPGVAYLFAGPLLVVEQLKRQLAIIHEAQRARGVPLDEG
                     WYQRLRAMPALIIPLTHNALNDLAIRGAALDMRAFRIHNRRTTLWAPADSTLQRVARY
                     TMILLMLTEFGAWIWLR"
     gene            complement(7456..8034)
                     /locus_tag="ACHY1N_002907"
     CDS             complement(7456..8034)
                     /locus_tag="ACHY1N_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFS4045191.1"
                     /translation="MARSHFSSQALVLIVISIAINMIGGQLASMVKLPIFLDSIGTLI
                     SAVLLGPVIGMLTGLLTNLLWGLLTDPIAAAFAPVAMVIGLVAGWLARAGWFRTLPKV
                     VVSGVIITLAVTVVAVPLRTALFGGVTGSGADLFVAWMHSMGQNLVESVAITVIGANL
                     VDKILTAVIVWLLLRQLPIRTTRHFPAMAAVR"
     gene            complement(8057..8488)
                     /locus_tag="ACHY1N_002908"
     CDS             complement(8057..8488)
                     /locus_tag="ACHY1N_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PPC domain-containing DNA-binding protein"
                     /protein_id="HFS4045192.1"
                     /translation="MMTLPYPYSSSARFYALRLLPGQEVFSQLHAFAQQHQLHAAWIA
                     GCTGSLTDVALRYAGQEGTTLLNGTFEVISLNGTLEQSGEHLHLCVSDPHGTMLGGHM
                     MPGCTVRTTLELVIGSLEELAFSRQPCALSGYDELHISPVK"
     gene            8860..9879
                     /gene="epd"
                     /locus_tag="ACHY1N_002909"
     CDS             8860..9879
                     /gene="epd"
                     /locus_tag="ACHY1N_002909"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0048001 - erythrose-4-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HFS4045193.1"
                     /translation="MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGV
                     YGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAG
                     ITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIV
                     DYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     TVAFR"
     gene            9929..11092
                     /gene="pgk"
                     /locus_tag="ACHY1N_002910"
     CDS             9929..11092
                     /gene="pgk"
                     /locus_tag="ACHY1N_002910"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFS4045194.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVND
                     VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            11307..12386
                     /gene="fbaA"
                     /locus_tag="ACHY1N_002911"
     CDS             11307..12386
                     /gene="fbaA"
                     /locus_tag="ACHY1N_002911"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFS4045195.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSK
                     YLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFQELNAIDVL"
     gene            complement(12450..12548)
                     /locus_tag="ACHY1N_002912"
                     /pseudo
     CDS             complement(12450..12548)
                     /locus_tag="ACHY1N_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518748.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12744..13604
                     /gene="mscS"
                     /locus_tag="ACHY1N_002913"
     CDS             12744..13604
                     /gene="mscS"
                     /locus_tag="ACHY1N_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HFS4045196.1"
                     /translation="MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLII
                     ARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADG
                     KIIVIPNGKIIAGNIINFSREPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKD
                     REMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKEDKAA"
     gene            13743..14378
                     /gene="argO"
                     /locus_tag="ACHY1N_002914"
     CDS             13743..14378
                     /gene="argO"
                     /locus_tag="ACHY1N_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0061459 - L-arginine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HFS4045197.1"
                     /translation="MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCA
                     ISDLVLICAGIFGGSALLMQSPWLLALVTWGGVVFLLWYGFGAFKTAMSSNIELASAE
                     VLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
                     FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS"
     gene            14471..15211
                     /gene="yggE"
                     /locus_tag="ACHY1N_002915"
     CDS             14471..15211
                     /gene="yggE"
                     /locus_tag="ACHY1N_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HFS4045198.1"
                     /translation="MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVSDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDNAIHQAQELANGFHRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQA
                     AIQFDDQVDVVFQLEPVDQQPAKTPAAQ"
     gene            15378..16274
                     /gene="ygfI"
                     /locus_tag="ACHY1N_002916"
     CDS             15378..16274
                     /gene="ygfI"
                     /locus_tag="ACHY1N_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417396.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4045199.1"
                     /translation="MDIFISKKMRNFILLAQTNNIARAAEKIHMSASPFGKSIAALEE
                     QIGYTLFTRKDNNISLNKAGQELYQKLFPVYQRLSAIDNEIHNSGRRSREIVIGIDNT
                     YPTIIFDQLISLGDKYEGVTAQPVEFSENGVIDNLFDRQLDFIISPQHVSARVQELEN
                     LTISELPPLRLGFLVSRRYEERQEQELLQELPWLQMRFQNRANFEAMIDANMRPCGIN
                     PTIIYRPYSFMAKISAVERGHFLTVIPHFAWRLVNPATLKYFDAPHRPMYMQEYLYSI
                     RNHRYTATMLQHIAEDRDGTNH"
     gene            complement(16271..17749)
                     /gene="scpC"
                     /locus_tag="ACHY1N_002917"
     CDS             complement(16271..17749)
                     /gene="scpC"
                     /locus_tag="ACHY1N_002917"
                     /EC_number="2.8.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionyl-CoA:succinate CoA transferase"
                     /protein_id="HFS4045200.1"
                     /translation="METQWTRMTADEAAEIIQHNDMVAFSGFTPAGSPKALPTAIARR
                     ANEQHEAKKPYQIRLLTGASISAAADDVLSDADAVSWRAPYQTSSGLRKKINQGAVSF
                     VDLHLSEVAQMVNYGFFGDIDVAVIEASALAPDGRVWLTSGIGNAPTWLLRAKKVIIE
                     LNHYHDPRVAELADIVIPGAPPRRNSVSIFHAMDRVGTRYVQIDPKKIVAVVETNLPD
                     AGNMLDKQNPMCQQIADNVVTFLLQEMAHGRIPPEFLPLQSGVGNINNAVMARLGENP
                     EIPPFMMYSEVLQESVVHLLETGKISGASASSLTISADSLRKIYDNMDYFASRIVLRP
                     QEISNNPEIIRRLGVIALNVGLEFDIYGHANSTHVAGVDLMNGIGGSGDFERNAYLSI
                     FMAPSIAKEGKISTVVPMCSHVDHSEHSVKVIITEQGIADLRGLSPLQRARTIIDNCA
                     HPMYRDYLHRYLENAPGGHIHHDLSHVFDLHRNLIATGSMLG"
     gene            complement(17773..18558)
                     /gene="scpB"
                     /locus_tag="ACHY1N_002918"
     CDS             complement(17773..18558)
                     /gene="scpB"
                     /locus_tag="ACHY1N_002918"
                     /EC_number="7.2.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA decarboxylase"
                     /protein_id="HFS4045201.1"
                     /translation="MSYQYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDLN
                     RPEIRCIILRAPSGSKVFSAGHAIHELPSGGRDPLSYDDPLRQITRMIQKFPKPIISM
                     VEGSVWGGAFEMIMSSDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKEL
                     IFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGE
                     AHTMNSDEFERIQGMRRAVYDSEDYQEGMNAFLEKRKPNFVGH"
     gene            complement(18569..19564)
                     /gene="meaB"
                     /locus_tag="ACHY1N_002919"
     CDS             complement(18569..19564)
                     /gene="meaB"
                     /locus_tag="ACHY1N_002919"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl Co-A mutase-associated GTPase
                     MeaB"
                     /protein_id="HFS4045202.1"
                     /translation="MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLL
                     DAIMPYCGNTLRLGVTGTPGAGKSTFLEAFGMLLIREGLKVAVIAVDPSSPVTGGSIL
                     GDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
                     ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLIVINKDDGDNHTNVAIARHMYE
                     SALHILRRKYDEWQPRVLTCSALEKRGIDEIWHAIIDFKTALTASGRLQQVRQQQSVE
                     WLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQLSEFIQTQYFD"
     gene            complement(19557..21701)
                     /gene="scpA"
                     /locus_tag="ACHY1N_002920"
     CDS             complement(19557..21701)
                     /gene="scpA"
                     /locus_tag="ACHY1N_002920"
                     /EC_number="5.4.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004494 - methylmalonyl-CoA mutase
                     activity [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="HFS4045203.1"
                     /translation="MSNEQEWQQLANKELSRREKTVDSLVQQTAEGIAIKPLYTEADL
                     DNLEVTGTLPGLPPYVRGPRATMYTAQPWTIRQYAGFSTAKESNAFYRRNLAAGQKGL
                     SVAFDLATHRGYDSDNPRVAGDVGKAGVAIDTVEDMKVLFDQIPLDKMSVSMTMNGAV
                     LPVLAFYIIAAEEQGVTPDKLTGTIQNDILKEYLCRNTYIYPPKPSMRIIADIIAWCS
                     GNMPRFNTISISGYHMGEAGANCVQQVAFTLADGIEYIKAAISAGLKIDDFAPRLSFF
                     FGIGMDLFMNVAMLRAARYLWSEAVSGFGAQDPKSLALRTHCQTSGWSLTEQDPYNNV
                     IRTTIEALAATLGGTQSLHTNAFDEALGLPTDFSARIARNTQIIIQEESELCRIVDPL
                     AGSYYIESLTDQIVKQARAIIQQIDEAGGMAKAIEAGLPKRMIEEASAREQSLIDQGK
                     RVIVGVNKYKLDHEDETDVLEIDNVMVRNEQIASLERIRATRDDAAVTAALNALTHAA
                     QHNENLLAAAVNAARVRATLGEISDALEVAFDRYLVPSQCVTGVIAQSYHQSEKSASE
                     FDAIVAQMEQFLADNGRRPRILIAKMGQDGHDRGAKVIASAYSDLGFDVDLSPMFSTP
                     EEIARLAVENDVHVVGASSLAAGHKTLIPELVEALKKWGREDICVVAGGVIPPQDYAF
                     LQERGVAAIYGPGTPMLDSVRDVLNLISQHHD"
     gene            complement(21905..22798)
                     /gene="argP"
                     /locus_tag="ACHY1N_002921"
     CDS             complement(21905..22798)
                     /gene="argP"
                     /locus_tag="ACHY1N_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator ArgP"
                     /protein_id="HFS4045204.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPES
                     RMMRKVTDALLDYGHKVLRQD"
     gene            22940..23125
                     /locus_tag="ACHY1N_002922"
     CDS             22940..23125
                     /locus_tag="ACHY1N_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001328908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045205.1"
                     /translation="MHFAQRVRALVVLNGVALLPLFAPWSGIPRPLYALFAGRKGMPA
                     IARYFMDELTTRLANGV"
     gene            23181..23840
                     /gene="rpiA"
                     /locus_tag="ACHY1N_002923"
     CDS             23181..23840
                     /gene="rpiA"
                     /locus_tag="ACHY1N_002923"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFS4045206.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGV
                     VTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            24096..25328
                     /gene="serA"
                     /locus_tag="ACHY1N_002924"
     CDS             24096..25328
                     /gene="serA"
                     /locus_tag="ACHY1N_002924"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFS4045207.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDD
                     EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK
                     NMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEK
                     ALQAMKAIPGTIRARLLY"
     gene            25557..25616
                     /gene="ibsC"
                     /locus_tag="ACHY1N_002925"
     CDS             25557..25616
                     /gene="ibsC"
                     /locus_tag="ACHY1N_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsC"
                     /protein_id="HFS4045208.1"
                     /translation="MMRLVIILIVLLLISFGAY"
     gene            25949..26008
                     /locus_tag="ACHY1N_002926"
     CDS             25949..26008
                     /locus_tag="ACHY1N_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HFS4045209.1"
                     /translation="MMRLAIILIVLLLISFPAY"
     gene            complement(26109..26711)
                     /gene="fau"
                     /locus_tag="ACHY1N_002927"
     CDS             complement(26109..26711)
                     /gene="fau"
                     /locus_tag="ACHY1N_002927"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFS4045210.1"
                     /translation="MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMM
                     TYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQ
                     SELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
                     HYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW"
     gene            complement(26732..26915)
                     /gene="ssrS"
                     /locus_tag="ACHY1N_002928"
     ncRNA           complement(26732..26915)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACHY1N_002928"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(26957..27286)
                     /gene="zapA"
                     /locus_tag="ACHY1N_002929"
     CDS             complement(26957..27286)
                     /gene="zapA"
                     /locus_tag="ACHY1N_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFS4045211.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKER
                     TRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITE
                     KTNQNFE"
     gene            27454..28032
                     /gene="ygfB"
                     /locus_tag="ACHY1N_002930"
     CDS             27454..28032
                     /gene="ygfB"
                     /locus_tag="ACHY1N_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YgfB"
                     /protein_id="HFS4045212.1"
                     /translation="MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDS
                     SWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH"
     gene            28058..29383
                     /gene="pepP"
                     /locus_tag="ACHY1N_002931"
     CDS             28058..29383
                     /gene="pepP"
                     /locus_tag="ACHY1N_002931"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HFS4045213.1"
                     /translation="MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPY
                     RQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEK
                     LGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYTYADEIVNSALEKLRKGSRQNLTAP
                     ATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHH
                     EFNRHGARYPSYNTIVGSGENGCILHYTENESELRDGDLVLIDAGCEYKGYAGDITRT
                     FPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKG
                     DVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPD
                     ADVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMAAARKQ"
     gene            29380..30558
                     /gene="ubiH"
                     /locus_tag="ACHY1N_002932"
                     /gene_synonym="visB"
     CDS             29380..30558
                     /gene="ubiH"
                     /locus_tag="ACHY1N_002932"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008681 - 2-octaprenyl-6-methoxyphenol
                     hydroxylase activity [Evidence IEA];
                     GO_function: GO:0016709 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, NAD(P)H as one donor, and incorporation
                     of one atom of oxygen [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HFS4045214.1"
                     /translation="MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPG
                     FDGRAIALAAGTCQQLARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLAAL
                     GQVVELHNVGQRLFALLRKAPGVMLHCPDRVANVARTQSHVEVTLESGETLTGRVLIA
                     ADGTHSALATACGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQHGPLAMLPMSDG
                     RCSLVWCHPLERREEVLSWSDEKFCRELQSAFGWRLGKITHAGKRSAYPLALTRAARA
                     ITHRTVLVGNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAHERGEDIGDYGILCRYQQ
                     RRQSDREATIGVTDSLVHLFANRWAPLVVGRNIGLMTMELFTPARDVLAQRTLGWVAR
                     "
     gene            30581..31783
                     /gene="ubiI"
                     /locus_tag="ACHY1N_002933"
                     /gene_synonym="visC"
     CDS             30581..31783
                     /gene="ubiI"
                     /locus_tag="ACHY1N_002933"
                     /gene_synonym="visC"
                     /EC_number="1.14.13.240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016709 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, NAD(P)H as one donor, and incorporation
                     of one atom of oxygen [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HFS4045215.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLVADA
                     PPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYS
                     HLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
                     IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPEEAQRMQQASEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYA
                     RQFAAHRLVLVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRR
                     YERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGL
                     NDLPEWLR"
     gene            complement(31857..31940)
                     /locus_tag="ACHY1N_002934"
     CDS             complement(31857..31940)
                     /locus_tag="ACHY1N_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045216.1"
                     /translation="MSKNTKSKNNDIRKYNAKTEVKLVYFK"
     gene            32230..33324
                     /gene="gcvT"
                     /locus_tag="ACHY1N_002935"
     CDS             32230..33324
                     /gene="gcvT"
                     /locus_tag="ACHY1N_002935"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HFS4045217.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDA
                     GMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLF
                     NDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREH
                     GTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            33348..33737
                     /gene="gcvH"
                     /locus_tag="ACHY1N_002936"
     CDS             33348..33737
                     /gene="gcvH"
                     /locus_tag="ACHY1N_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005960 - glycine cleavage complex
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HFS4045218.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTFTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            33856..36729
                     /gene="gcvP"
                     /locus_tag="ACHY1N_002937"
     CDS             33856..36729
                     /gene="gcvP"
                     /locus_tag="ACHY1N_002937"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HFS4045219.1"
                     /translation="MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQ
                     IVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQ
                     QVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPIGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAGVLTRAEAAEINLRSDILNAVGITLDETTTRENVMQLFNVLLGDNHGLDID
                     TLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQD
                     AFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQNELVAEWAHP
                     YSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ"
     gene            36990..37733
                     /gene="ygfF"
                     /locus_tag="ACHY1N_002938"
     CDS             36990..37733
                     /gene="ygfF"
                     /locus_tag="ACHY1N_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4045220.1"
                     /translation="MVIALVTGGSRGIGRATALLLAQEGYTVAVNYQQNLHAAQEVMN
                     LITQAGGKAFVLQADISDENQVVAMFTAIDQHDEPLAALVNNAGILFTQCTVENLTAE
                     RINRVLSTNVTGYFLCCREAVKRMALKNGGSGGAIVNVSSVASRLGSLGEYVDYAASK
                     GAIDTLTTGLSLEVAAQGIRVNCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQA
                     EEVAQAIVWLLSDKASYVTGSFIDLAGGK"
     gene            complement(37790..39223)
                     /gene="bglA"
                     /locus_tag="ACHY1N_002939"
     CDS             complement(37790..39223)
                     /gene="bglA"
                     /locus_tag="ACHY1N_002939"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="HFS4045221.1"
                     /translation="MKKLTLPKDFLWGGAVAAHQVEGSWNKGGKGPSICDVLTGGAHG
                     VPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEA
                     QPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAE
                     VVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFV
                     ASALAVKAARRINPEMKVGCMLAMVPLYPYCCNPDDVMFAQESMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYALCELYERYQRPLFIVENGFGAYDKVEEDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDD
                     GAGDMSRSRKKSFNWYQEVIASNGEKL"
     gene            39268..39579
                     /gene="yqfB"
                     /locus_tag="ACHY1N_002940"
     CDS             39268..39579
                     /gene="yqfB"
                     /locus_tag="ACHY1N_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-acetylcytidine aminohydrolase"
                     /protein_id="HFS4045222.1"
                     /translation="MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRF
                     EDDGYFCTIEVTATSTVRLDTLTEKHAEQENMTLTELKKVIADIYPGQTQFYVIEFKC
                     L"
     gene            39743..40402
                     /gene="yqfA"
                     /locus_tag="ACHY1N_002941"
     CDS             39743..40402
                     /gene="yqfA"
                     /locus_tag="ACHY1N_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFS4045223.1"
                     /translation="MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDL
                     NASATAITSYSLYGGSMILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
                     VKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQ
                     A"
BASE COUNT         9630 a        10073 c        10895 g         9813 t
ORIGIN      
        1 ccggtttccc tgctcaattg ctttcattaa accgcacgag tattttattt ttaccgccgg
       61 acggtaccct aaaaataaaa taaggataat ttatgcggct tagtgactat tttccagaat
      121 catcaatctc agttatacat tcagcaaaag attggcagga agctatcgat ttctcgatgg
      181 tatcattgct ggataaaaac tatatcagcg agaattacat tcaggcaatt aaagattcca
      241 ccattaacaa tggcccttat tatattctcg caccaggcgt ggcaatgcct catgcgcgac
      301 cggaatgtgg ggcgcttaaa accgggatgt ctttgacatt acttgaacaa ggtgtttatt
      361 ttccggggaa tgacgaacca attaaattac tcatcggact ctctgctgcc gatgccgatt
      421 cgcacattgg cgctattcag gcgttaagtg aattactgtg cgaagaagaa atactcgaac
      481 aactcttaac agcatcatca gaaaaacaat tagcggacat tatcagccgc ggataattac
      541 tctctcctct acaggataat attatggaaa acaagtctgc tcgtgcaaag gtccaggctt
      601 ttgggggctt tttgactgca atggtcatcc ccaatatagg tgcttttatt gcctggggct
      661 tcataactgc gttatttatt cccaccggtt ggctgccgaa tgaacatttc gccaaaattg
      721 tcggcccgat gattacctat ttattgcccg tgatgattgg ttctactggt ggtcatctgg
      781 tcggcggtaa acgcggggcg gtcatgggcg gaataggtac tattggtgtg atcgttggcg
      841 cagagatccc gatgttcctt ggctcaatga tcatggggcc gctcggtggg ttggtcataa
      901 aatatgtcga taaggcactg gaaaaacgca tacctgccgg ttttgagatg gttatcaata
      961 acttctcatt aggtatcgcg gggatgctcc tttgtctgct gggttttgaa gtgatcggcc
     1021 cggcggtgtt aattgccaat actttcgtca aagagtgtat cgaggcgctg gtacatgcgg
     1081 gttatctgcc tctgctgtca gtcatcaatg aaccggcgaa agtgcttttc cttaataatg
     1141 cgatcgatca gggcgtctat tatccgctgg gaatgcaaca ggcttcggtt aacggtaaat
     1201 ccatcttctt tatggtggcc tctaacctag gtccgggcct ggggctgctg ctggcgttta
     1261 ccttgtttgg taaagggatg agtaaacgtt ctgcgcccgg ggcgatgatt attcacttcc
     1321 tcggtgggat ccacgaactg tatttcccat atgtgctgat gaagccgctg actattattg
     1381 ccatgattgc gggcggtatg tctggtacct ggatgtttaa cttactggac ggtggtctgg
     1441 tggctggccc aagtccgggg tctatctttg cttacctggc actgacgccg aaaggctcgt
     1501 tcctggcgac aattgccggt gttacggtag gtaccctggt gtcctttgct attacttcgc
     1561 tgatactgaa gatggaaaaa acggtggaaa cggagagcga agatgagttt gctcagtcag
     1621 ccaatgcggt taaggcgatg aaacaagagg gtgcattctc gttaagcagg gttaagcgta
     1681 tcgcctttgt ttgcgatgcg gggatgggct ccagtgcgat gggcgcgacc accttccgta
     1741 aacgcctgga aaaagcgggg ctggcaatag aagtaaaaca ttacgcgata gaaaacgtgc
     1801 ctgcggatgc cgatatcgtc gtcactcacg ccagtctgga agggcgcgtg aaacgtgtga
     1861 cggataaacc gctgatattg attaataact atattggcga tccaaaactc gacactttat
     1921 ttaatcaatt aaccgccgaa cataaacact gattacagag gtaaaaatga aaaccaaagt
     1981 tgctgctatt tatggcaagc gggatgtccg tctgcgcgaa tttgaactgc cagaaattac
     2041 cgataatgaa ctgttagtga gtgtaatttc tgacagcgtc tgtttatcga cctggaaagc
     2101 ggcgttactc ggtagtgaac ataaacgcgt acccgacgat ttagaaaatc atccggtcat
     2161 taccgggcat gaatgtgccg gggttattgt cgaagtgggt aaaaatctca ctggcaaata
     2221 taaaaaaggc cagcgttttg tattgcaacc ggcgatgggg ttaccaagcg gatattcagc
     2281 aggctacagc tacgaatatt ttggcggtaa cgccacctat atgattattc ccgaaatcgc
     2341 cattaatttg ggctgcgtat taccgtatca cggctcttat tttgctgcgg cgtcgctggc
     2401 agagcctatg tgctgcatta ttggtgctta tcatgccaat tatcacacca cgcaatatgt
     2461 ttatgagcat cgcatgggcg tcaaacctgg cggcaatatt gcactgctgg cgtgtgcggg
     2521 tccgatgggc attggcgcta tcgattacgc cattaacggt ggcatacaac cgtcacgggt
     2581 ggtggtggtc gatatcgacg acaaacgcct ggcgcaggtg cagaagctgc tgccggtgga
     2641 tctggcggcc agtaaaggca ttgagctggt gtatgtgaat accaaaggga tgagcgatcc
     2701 ggtccagacg ctgcgggcgc tgacaggaga tgtcgggttc gatgacattt ttgtttatgc
     2761 ggcggtgcct gctgtcgttg agatggctga cgaattactg gcggaagatg gctgtctgaa
     2821 cttctttgcc gggccgacgg ataaaaactt caaagtgccg tttaatttct acaacgtcca
     2881 ttacaacagc acgcacgtag tcggtacatc cggcggttca acggacgaca tgaaagaggc
     2941 gattgcgtta agcgccacgg ggcagttgca gccgtccttt atggtcacgc atatcggtgg
     3001 gctggatgcg gtgccagata ccgtgctcaa tctgccggat atccctggcg gtaaaaaact
     3061 catttataac ggcgtgacca tgccgctcac tgccattgcc gattttgccg aaaaaggcaa
     3121 aaccgatccg ctgtttaaag agttggcgcg gctggttgag gaaacgcacg gcatctggaa
     3181 tgaacaggcc gagaaatatc tgctggcaca atttggcgtt gatatcgggg aggccgcgca
     3241 atgatgtccc tggcgtggcc attatttcgc gttacggaac aggcagcgtt ggctgcctgg
     3301 ccgcaaaccg gatgtggcga caaaaataaa attgatggcc tggcggtcac cgcgatgcgc
     3361 caggcattaa acgacgtcgc ttttcgtgga cgagtggtta tcggcgaagg agaaattgac
     3421 catgcgccga tgctgtggat tggcgaagag gtgggcaaag gcgatgggcc agaagtcgat
     3481 atcgcggttg acccgattga aggcacgcgg atggtagcga tggggcagag caatgcgctg
     3541 gcggtcatgg ctttcgcccc tcgagatagc ctgttacatg cgcccgatac gtatatgaaa
     3601 aagctggttg ttaatcgact ggcggcgggc gcgattgatc tgtctttgcc tctggcggac
     3661 aacttgcgca acgtggcgaa agcgttaggt aaaccgctgg acaagctgcg catggttacg
     3721 ctggataaac cgcgcctgag tgccgcgatt gaagaagcaa cacagctggg cgtgaaggtt
     3781 ttcgctctgc cggatggcga tgtcgccgcc agcgtgctga cctgctggca ggataatcct
     3841 tacgacgtga tgtacaccat cggcggtgcg ccagaaggcg tgatttctgc ctgtgccgtt
     3901 aaagcattag gtggggatat gcaggccgag ctgattgact tttgtcaggc taaaggggat
     3961 tacacggaaa atcggcagat tgcagagcag gagcgcaagc gttgtaaggc aatgggcgtt
     4021 gacgttaacc gtgtgtactc gctcgatgaa ctggtgaggg ggaacgatat cctctttagc
     4081 gctacgggcg tgacgggcgg cgagttggtg aacggtatcc aacagacggc gaatggggtg
     4141 cggacgcaga cattactgat cggcggcgcg gaccaaacgt gtaatataat agactccctg
     4201 cattgatggt gatctatcgg aagaccaatg gcgacgctga cagaagatga tgtgcttgag
     4261 caactggatg cacaggacaa tttattttca tttatgaaaa ctgcgcattc tattttgctc
     4321 caggggatac gccagtttct gccgtcgctg tttgtcgata acgatgaaga gatcgtcgaa
     4381 tatgcagtga agccgttact cgcccaaagc ggcccgcttg acgatattga tgttgcgctg
     4441 cgtttgattt atgcgctggg gaaaatggat aaatggctgt atgccgatat cacgcacttt
     4501 tcccagtact ggcattacct gaacgaacag gatgaaacgc ccggatttgc cgatgacatg
     4561 acctgggatt ttatcagcaa cgtcaatagc ataacctgca atgcgacgct ctatgacgcg
     4621 ttaaaagcga tgaagttcgc cgatttcgcc gtctggtcag aggcgcgttt tagcggaatg
     4681 gtcaaaacgg cgctgacgct ggcagtaacg accaccttaa aggaattaac gccgtgaaaa
     4741 ttgaattaac ggtgaatggg ctgaacgtgc aagcgcagta ccatgatgaa gagatagaac
     4801 gcgtgcataa accgttgctg cgtatgctgg cggccttaca gacggtaagt ccgcagcgac
     4861 gtacggtggt ttttctttgc gctccgccgg ggacgggtaa atctacctta actaccttct
     4921 gggaatatct cgcgcaacaa gaccctgaat tacccgctat ccagacgctc ccgatggatg
     4981 gttttcacca ttacaatagc tggctggatg cgcatcaatt gcgccccttc aaaggcgcac
     5041 cagagacatt tgacgttgcg aaactggcgg aaaatctgtg ccaggtagtg gaaggggatt
     5101 gtacgtggcc gcagtatgat cgacaaaagc atgatcctgt tgaagatgcg ttgcacgtta
     5161 ccgcaccact cgtcatcgtc gaaggaaact ggttgttgct ggacgacgag aagtggtgcc
     5221 agcttgcgca attttgtgat ttctcgatct ttatcaacgc gccagctact gcgttgcggg
     5281 aacgactggt agggcgcaag ctggcgggag gggtatcgct ggcagacgca gaagcttttt
     5341 atgaccgtac cgacgggccg aatgttcgcc gggtgctgga agagagtctg cctgcaaatt
     5401 tgaccttaat gatgaccgct acgggtgaat atcgtctggt ggattaacgt tcctgattag
     5461 accatcttcc agtcgcacca cacgagagaa atgacgccgg gtaaatgcgg cgtcatgact
     5521 gattgctacg acgctcgtgc ctcgctggcc gcacttctcc agccagcttt caaacacgct
     5581 caaccaattt tcgtcaaaat cccgactcgg ctcgtccagc agcaatagtg gcggagagag
     5641 tgcttccagg caggcgacgg cgaccatccg tcgctgcgca ctatgcagat ccaacgggtg
     5701 cgagttggca gtgtctgcta actgacaaca ttgccatggg tacgttgagt gatttcatcc
     5761 gccgggcatt tttgcagttt caaaccaaat gcgatctcgt cagcgacggt gctgtgaaaa
     5821 agttggtttt ccgcttcctg aaacagtacg ccaacctttg ccgcgcgctg gcggtttttc
     5881 aggtttttca tcgcctgttg ttgcagcata accgtaccgg ctgtgggcct aagaagacct
     5941 gccattactc gtaacagcgt cgatttccct gcgccattgt caccggtcag cgccaaccat
     6001 tcaccttgtt tgagttgcag agaaatgtcg caaagacaat ccgttgccgc gccaggccag
     6061 cgataagata tcttatttaa cgttaacata gtggctggag cgctccgttt tgcaattgcc
     6121 acgcttgctg gcagtagttc aggaaaggtg tgcgatgacg ttcaaaaaga ataatcagcg
     6181 aaccacgttc aaacgcccag tgttgtaagc gctgcaacag catttcgctg gcctgcggag
     6241 tcaggcggct aaaggcttca tcaagaatta agagctttgg ctgcatcgcg atggcgcagg
     6301 cgatgaccac gcgctgtgtc tctccaccgg agagtgttgc cgggtgacga tggcgcaacg
     6361 gctggcactc ggtcagagtc agggcggcat caatccgcgc cataatctct gcttcagcaa
     6421 gacacagatt ttctggccca aaggcaactt cttcttccac gctaaaggta cagccggaga
     6481 gctgcaaata gggcgattgc tggacgagct ggatggtggc ggattgttca ttaagcggga
     6541 gatgcccaat gggcgtaccg aggagcgtcc ccgtgcctgt tatctctcct ggcagaaagt
     6601 ccggatacca gcccgccatc agctgtgcca gcgtactttt gccactgccg ttgtcaccaa
     6661 agatggcgac catccccggt ttgacatagt gaaagtcata acagaacgga ggatgcgttg
     6721 agtgtgtcgg gcaataacgg aactgttcta acgtaaccat atccacgctc cgaattctgt
     6781 cagcatcagc aagatcatgg tgtaacgcgc tacgcgttgt agggtgctat cggctggtgc
     6841 ccacaacgtt gttcgtcggt tgtggatccg aaatgcccgc atatccagcg ccgcaccacg
     6901 gatagccaga tcgtttagcg cattgtgtgt tagcggaata attaacgcgg gcatcgcacg
     6961 taaacgctga taccagccct catccagcgg cacgccacgg gcacgctgcg cttcatgaat
     7021 aatcgctaat tgccgtttta actgctcaac gaccaataac ggcccggcaa acagataagc
     7081 gacgcctggc ggcaggcgag aagcaaacag agcgcgaata aaacattgca cggggacgta
     7141 ctgcatccac aactgtgagg ttgaaacaat cgccagaatc cgcaaccaga gcgtaatagc
     7201 atgcgaccac cgttctggcg agcgtggcgt gccgcttagc cattctggta gccagccacc
     7261 gtgtaccagc cacagcccgg ctcccagcga gaacatcagc cagacgacat attttgcccg
     7321 ccgtcgcgtg gcctttagcg caataaggca gaaaaaggtc gccgcgctat agatcggcaa
     7381 aatggtctgc gcgggcagga taagcgtggt gcaggccgcc aatgcccaca gtgttaatga
     7441 ggtaaatgga tgcatttagc gcacggcagc cattgccgga aaatggcgcg tggtgcgaat
     7501 cggcagctgg cgcagtaaaa gccagacaat caccgctgta agaattttat cgaccaggtt
     7561 cgcgcctatc accgtaatcg ccaccgactc caccaggttt tgccccatcg agtgcatcca
     7621 ggcaacgaac aaatcggctc cgctaccggt gacaccgccg aacagcgcag tacgcagcgg
     7681 tacagcgacg accgttaccg caagcgtaat aatcacgccg ctgacaacga cttttggcag
     7741 ggtgcgaaac caacccgctc gcgccagcca accggcgacc aggccgatga ccatcgcgac
     7801 gggtgcaaat gcggcggcga tcgggtcggt cagcaatccc cagagtaaat tggtcagtaa
     7861 gccggtcagc attccgatca ccggaccaag cagtaccgcg ctaataagtg tgccgatgga
     7921 gtcgagaaat ataggtaatt tgaccatgct ggccagttgc ccgccgatca tattgatggc
     7981 gatagatata acgatcaaca ccagtgcctg actggaaaag tggctacgcg ccataagaaa
     8041 acctctttga aagtagttat ttaacggggg aaatatgcaa ctcgtcgtaa ccagaaagcg
     8101 cgcaaggttg gcggctaaac gccagttcct caaggctacc gatcaccagt tcaagcgtgg
     8161 tccgcacggt acagccgggc atcatatgac cgccaagcat cgtgccgtgt ggatcggaaa
     8221 cgcagagatg aagatgctca ccactctgtt ccagcgtgcc gtttagtgag atcacttcga
     8281 atgtaccgtt caggagcgtg gtgccttctt gcccggcata gcgcaaggcg acgtcagtca
     8341 ggctaccggt acagcctgca atccaggcgg catgaagttg atgctgctgt gcaaaagcgt
     8401 gtagctggga aaaaacttcc tgcccgggga ggaggcgcag tgcgtaaaag cgtgcggagg
     8461 aagaatatgg gtagggcaat gtcatcattg gagtactccg aaactcggac gtattgcgga
     8521 taatatcgac gttgcatcag tcatattctg atataagtca gggtttgtga cggcacaacg
     8581 aaaagatttt gctacgctta ttcgtgattc tgcaaagtgg aataaattcc acaggggcgg
     8641 ggctgaaaac gtgacgtaag tcagataatt gctttctttg actggacaat cattcctttt
     8701 attccacgtt tcgcttatcc tagctgaagc gtttcagtcg attaaatgtt cgacaattaa
     8761 ccaatcagtc gcagtttgcg acaggtaagg tttccccgga cgatttgctg gattactctg
     8821 tctggcaaat ttgctcaggg aaaaccttgc aggagatcta tgaccgtacg cgtagcgata
     8881 aatggcttcg gtcgcatcgg gcgtaatgtg gttcgtgctt tgtatgaatc cggacgccgg
     8941 gcggaaatta ccgtggtggc aatcaacgaa ctggcggatg ctgcgggcat ggcgcatttg
     9001 ttgaaatatg acaccagcca tggccgtttt gcatgggaag tacgacagga acgcgatcaa
     9061 ctttttgttg gtgatgacgc catccgcgta ttgcatgaac gttcactgca atcgctcccc
     9121 tggcgtgaac ttggcgttga tgtagtcctc gactgcaccg gcgtatatgg ctcccgcgag
     9181 catggcgaag cgcatattgc cgccggggcc aaaaaagtgc tcttttcaca tcctggcagt
     9241 aacgatctcg acgcgaccgt tgtttacggc gtcaatcagg atcaacttcg tgcggaacac
     9301 cgcatcgttt ctaacgcttc ctgtaccacg aattgcataa ttcccgtcat caaattgtta
     9361 gatgatgcgt acggtattga gtccggcact gtgaccacaa ttcactccgc catgcacgat
     9421 caacaggtta ttgatgcata ccatcctgac ctgcgtcgca cccgggcagc cagccagtcg
     9481 atcattccgg tcgatactaa actggccgcc ggtatcacac gattttttcc gcaatttaac
     9541 gatcgctttg aagcgattgc ggtacgtgtg ccaaccataa atgtgacggc aatcgattta
     9601 agcgtgacgg tgaagaaacc tgtaaaagcc aatgaagtca acctgttgct gcaaaaagca
     9661 gcacaaggtg catttcatgg tatagttgac tatacggaat tgccgttggt ctctgtagat
     9721 tttaaccacg atccgcacag tgccattgtc gatggcaccc aaacccgggt cagtggcgca
     9781 cacctgatca aaacgttggt ctggtgcgat aacgaatggg gctttgctaa ccgaatgctc
     9841 gacacgacgt tagctatggc tactgttgct ttcaggtaag acgcaagcag cgtctgcaaa
     9901 acttttagaa tcaacgagag gattcaccat gtctgtaatt aagatgaccg atctggatct
     9961 tgctgggaaa cgtgtattta tccgtgcgga tctgaacgta ccagtaaaag acgggaaagt
    10021 aaccagcgac gcgcgtatcc gtgcttctct gccgaccatc gaactggccc tgaaacaagg
    10081 cgcaaaagtg atggtaactt cccacctggg tcgtcctacc gaaggcgagt acaacgaaga
    10141 attctctctg ctgccggttg ttaactacct gaaagacaaa ctgtctaacc cggttcgtct
    10201 ggttaaagat tacctcgacg gcgttgacgt tgctgaaggt gaactggttg ttctggaaaa
    10261 cgttcgcttc aacaaaggcg agaagaaaga cgacgaaacc ctgtccaaaa aatacgctgc
    10321 actgtgtgac gtgttcgtaa tggacgcatt cggtactgct caccgcgcgc aggcttctac
    10381 tcacggtatc ggtaaattcg ctgacgttgc gtgcgcaggc ccgctgctgg cagctgaact
    10441 ggacgcgctg ggtaaagcac tgaaagaacc tgctcgcccg atggtggcta tcgttggtgg
    10501 ttctaaagta tctaccaaac tgaccgttct ggactccctg tctaaaatcg ctgaccagct
    10561 gattgttggt ggtggtatcg ctaacacctt tatcgcggca caaggccacg atgtgggtaa
    10621 atccctgtac gaagctgacc tggttgacga agctaaacgt ctgctgacca cctgcaacat
    10681 cccggttccg tctgatgttc gcgtagcaac cgagttctct gaaactgcac cggctaccct
    10741 gaaatctgtt aacgatgtga aagctgacga gcagatcctg gatatcggtg atgcttccgc
    10801 tcaggaactg gctgaaatcc tgaagaatgc gaaaaccatt ctgtggaacg gtccggttgg
    10861 cgtgttcgaa ttcccgaact tccgcaaagg tactgaaatc gtggctaacg ctatcgcaga
    10921 cagcgaagcg ttctccatcg ctggcggcgg cgacactctg gcagcaatcg acctgttcgg
    10981 cattgctgac aaaatctcct acatctccac tggcggcggc gcattcctcg aattcgtgga
    11041 aggtaaagta ctgcctgcag tagcgatgct cgaagagcgc gctaagaagt aaaaaatcac
    11101 agggcaggga aacctgccct tgtttcagcg cgcttttaga gcacgcattt tttcatactc
    11161 taaataattc gagttgcagg aaggcgacaa gagagtgaat ccccaggagc ttacataagt
    11221 aagtgactgg ggtgagcgaa cgcagacgca gcacatgcaa cttgaagtat gatgagtata
    11281 aggcccgacg atacaggaca agagacatgt ctaagatttt tgatttcgta aaacctggcg
    11341 taatcactgg tgatgacgta cagaaagttt tccaggtagc aaaagaaaac aacttcgcac
    11401 tgccagcagt aaactgcgtc ggtactgact ccatcaacgc cgtactggaa accgctgcta
    11461 aagttaaagc gccggttatc gttcagttct ccaacggtgg tgcttccttt atcgctggta
    11521 aaggcgtgaa atctgacgtt ccgcagggtg ctgctatcct gggcgcgatc tctggtgcgc
    11581 atcacgttca ccagatggct gaacattatg gtgttccggt tatcctgcac actgaccact
    11641 gcgcgaagaa actgctgccg tggatcgacg gtctgttgga cgcgggtgaa aaacacttcg
    11701 cagctaccgg taagccgctg ttctcttctc acatgatcga cctgtctgaa gaatctctgc
    11761 aagagaacat cgaaatctgc tctaaatacc tggagcgtat gtccaaaatc ggcatgactc
    11821 tggaaatcga actgggttgc accggtggtg aagaagacgg cgtggacaac agccacatgg
    11881 acgcttctgc actgtacacc cagccggaag acgttgatta cgcatacacc gaactgagca
    11941 aaatcagccc gcgtttcacc atcgctgcgt ccttcggtaa cgtacacggt gtttacaagc
    12001 cgggtaacgt ggttctaact ccgaccatcc tgcgtgattc tcaggaatat gtttctaaga
    12061 aacacaacct gccgcacaac agcctgaact tcgtattcca cggtggttcc ggttctactg
    12121 ctcaggaaat caaagactcc gtaagctacg gcgtagtgaa aatgaacatc gataccgata
    12181 cccaatgggc aacctgggaa ggcgttctga actactacaa agcgaacgaa gcttatctgc
    12241 agggtcagct gggtaacccg aaaggcgaag atcagccgaa caagaaatac tacgatccgc
    12301 gcgtatggct gcgtgccggt cagacttcga tgatcgctcg tctggaaaaa gcattccagg
    12361 aactgaacgc gatcgacgtt ctgtaagata ttcctttctg cttatctcaa ggcccgctct
    12421 gcgggtcttt ttttcgccaa aagcaaaatt gcctgatgcg ctacgcttat caggcctaca
    12481 cgtatcctgc aatatattga atttgcaggt ttttgtaggc cggataaggc gttcacgccg
    12541 catccggcat gacaaagcgc acattgatat ctgtctgagc cccgctctgc ggggattttt
    12601 tcgccaaaag caaggtgatt cagatgagaa atctgtgatc tatttggcaa aattatgctt
    12661 tattgtttac ccttgtcaga ctgcccgtca taaggcggcg gagtgtattt ctccattttg
    12721 agtcagttga aaaggaatat tgaatggaag atttgaatgt tgtcgatagc ataaacggcg
    12781 cgggaagctg gctggtagct aaccaggcgc tgctgctaag ttatgcagta aacatcgtgg
    12841 cggcactcgc gatcatcatc gttggtttga ttatcgcgcg gatgatttcc aacgcggtga
    12901 atcgcctgat gatctcccgt aaaatcgatg ccactgttgc tgattttctt tctgcattag
    12961 tccgttacgg tattatcgcc tttacgctaa tcgctgccct gggacgcgtg ggtgtacaaa
    13021 cagcgtcagt cattgctgta ctcggtgccg caggcttagc tgttggtctg gctttgcagg
    13081 ggtcactttc taacctggcc gctggcgtgt tacttgtcat gttccgcccg ttccgtgccg
    13141 gagaatatgt tgacctcggc ggcgtagccg gtactgtgct gagtgtgcag attttctcca
    13201 ccaccatgcg tactgcagac ggtaaaatta tcgttattcc gaacggtaaa attattgccg
    13261 gaaatattat taacttctcc cgcgagccag ttcgccgtaa cgaatttatt attggcgtgg
    13321 cgtatgattc cgatatcgat caggttaagc agatcctgac caatattatc cagtctgaag
    13381 atcgcatttt gaaagatcgc gaaatgactg tgcgcctgaa cgaacttggt gcatcgtcga
    13441 ttaatttcgt ggtccgcgtc tggagcaaca gcggcgatct gcaaaacgtg tactgggatg
    13501 tgctggagcg tattaaacgt gaatttgatg ccgccggtat cagcttcccg tacccgcaaa
    13561 tggatgtgaa ctttaagcgg gtgaaagaag acaaagctgc gtaatcaacg ctgaggccag
    13621 ataatactct ctggcctctc tcttattagt tattctgatt gccaattaat attatcaatt
    13681 tccgctaata acaatcccgc gatatagtct ctgcatcaga tacttaattc ggaatatcca
    13741 acgtgttttc ttattacttt caaggtcttg ctcttggggc agctatgatt ctgccgctcg
    13801 gcccacaaaa tgcttttgtg atgaatcagg gcattcgtcg tcagtaccac attatgattg
    13861 ccttactttg cgctatcagc gatttggtcc tgatttgcgc ggggattttt ggtggtagcg
    13921 cgttattgat gcagtcgccg tggttgctgg cgctggtcac ctggggcggc gtagtcttct
    13981 tgctctggta tggttttggc gcttttaaaa cagcgatgag tagtaatatt gagttagcta
    14041 gtgccgaagt cctgaagcaa ggcagatgga aaattatcgc caccatgttg gcagtgacct
    14101 ggctgaatcc gcatgtttac ctggatactt ttgttgtact gggcagcctt ggcgggcagc
    14161 ttgacgtcga accaaaacgt tggtttgcgc tcgggacaat tagcgcctct ttcctgtggt
    14221 tctttggtct ggctattctc gcagcctggc tggcaccgcg cctgcgcacg gcaaaatcac
    14281 agcgcattat caatctggta gtgggatgtg tcatgtggtt tatagccttg cagctggcga
    14341 gagacggtat tgctcatgca caagccttgt tcagttaggc gctatctgat ggaaaaataa
    14401 aacagaggcg ctaagcttgc ctccagaggt cctgagtttt gggcaagtca attaacacgg
    14461 agagactaac gtgaagttca aagttatcgc cctggcggca ttaatgggta ttagcgggat
    14521 ggcagcgcag gctaacgaat tgccggatgg accgcatatt gtcacctccg gtacggcaag
    14581 tgtggatgcg gtgtcagaca ttgccactct tgcgattgaa gttaacgtgg ccgcgaagga
    14641 tgccgctaca gccaagaaac aggcagatga gcgcgtcgca caatacattt ccttccttga
    14701 actcaatcag atcgcgaaaa aagatatcag ctcagcgaat ttacgcaccc agccagatta
    14761 tgattatcag gatggtaaaa gtatcctgaa aggctaccgc gctgtgagaa cggtggaagt
    14821 cacgctccgt cagttagaca aactgaattc cttgctggat ggcgcgctga aggcgggtct
    14881 taacgaaatt cgttctgtgt cgctgggcgt ggcgcagcct gatgcctata aagacaaagc
    14941 gcgtaaggca gcgattgata acgcgattca tcaggcgcag gaactggcga acggctttca
    15001 tcgtaaactg gggccggtat atagcgtgcg ctaccatgtt tccaactatc agcccagccc
    15061 aatggtgcgg atgatgaaag ccgatgccgc gccggtgtct gcccaggaaa cttacgagca
    15121 ggccgctatt cagtttgatg atcaggtcga tgtggtcttc cagttagaac ctgtggatca
    15181 acaacccgct aaaacacctg cagcacaata atacttgtag cccgacgtat tcgtcgggct
    15241 aatgccttta cccgatattg cctccttttt ctgtaatttt ctgtaaaacc atgacgtaat
    15301 cacctatctt tgctcgcggt ttcatcaagg ataggctgac tgaaacggtt aagcggacaa
    15361 ggatgcgggg aggggggatg gacattttta tttcgaaaaa gatgcgcaat ttcattttat
    15421 tagcgcaaac caataatatt gcccgggcgg cagaaaaaat ccatatgtcg gcttcgccat
    15481 ttggtaaaag cattgccgcg ctggaagaac aaattggcta tacgctattt acccgcaaag
    15541 ataataatat cagcctcaat aaagccggtc aggaactgta tcaaaaactg ttcccggttt
    15601 atcaacgact ttctgcgatt gataatgaaa tccataactc agggcgtcgt tcacgagaaa
    15661 ttgtgattgg catagataat acttatccga caattatttt cgatcagttg attagtctcg
    15721 gagataagta tgaaggcgtg accgcccagc cagttgagtt cagcgaaaac ggcgttatcg
    15781 ataatctttt tgaccgtcag ttagatttta ttatctcccc acagcatgta tctgcacgag
    15841 ttcaggaact ggaaaacctg actatcagtg aattaccacc gctgcgattg ggctttctcg
    15901 tttctcgccg ttatgaagag cgtcaagagc aagagctgct tcaggagctg ccctggctac
    15961 aaatgcgctt tcaaaaccgg gctaacttcg aagcaatgat tgatgcgaat atgcgacctt
    16021 gtgggatcaa tcccaccatt atttatcgtc cctacagttt tatggccaaa atcagcgccg
    16081 tggagcgcgg acattttctg acggtgatcc cgcattttgc ctggcgactg gtgaatccgg
    16141 caacgctgaa atattttgat gcgccgcaca ggccgatgta tatgcaggaa tatctttatt
    16201 caatcagaaa tcatcgttat accgccacga tgcttcagca tattgctgaa gatcgtgacg
    16261 ggacaaacca ttaacccagc atcgagccgg ttgcaattaa attacggtgt aagtcgaaga
    16321 cgtggctaag atcgtggtga atatgtccgc cgggcgcatt ttccagatag cgatgcagat
    16381 aatcccgata cataggatgt gcacaattat caatgatagt gcgggcgcgt tgaagcgggg
    16441 aaagaccgcg cagatcggcg atcccttgtt cggtgatgat cactttgacg ctgtgttcgc
    16501 tgtgatcaac atggctgcac attggcacga cggttgagat cttgccttct ttagcaatcg
    16561 acggagccat aaagatcgac agatacgcgt tgcgttcaaa atcaccgctg ccgccgatgc
    16621 cgttcatcag atcgaccccg gctacgtgcg ttgagttggc atgcccgtaa atatcaaact
    16681 ccaggccgac gttcagagcg atgacgccca gacgacggat gatttccggg ttattggaaa
    16741 tctcctgcgg acgcaacaca atgcggctgg caaagtaatc catattgtcg taaatcttgc
    16801 gcagggaatc ggccgagatt gtcaggctgg aggcgctggc cccgctgatt ttgccggttt
    16861 ccagtaaatg caccaccgat tcctgtagca cttccgaata catcataaac ggaggaattt
    16921 ccgggttttc ccccagacgc gccattaccg cattattgat attgcccacg ccactttgca
    16981 gcggcagaaa ttccggcgga atacgcccat gcgccatttc ctgcaataag aacgtgacca
    17041 cgttatcggc aatctgctgg cacatgggat tttgcttatc cagcatatta ccggcgtcgg
    17101 gcaagttggt ttccacgacg gcgacaatct ttttcggatc gatttgcaca tagcgggtac
    17161 cgacgcgatc cattgcatgg aagatcgaca cgctattgcg ccgcggtggc gcgccaggaa
    17221 tcacaatatc cgccagttct gcaacgcgcg gatcgtgata gtgattaagt tcaatgatca
    17281 ctttcttcgc ccgcagcagc catgtcggcg cattaccgat cccgctggtt aaccagactc
    17341 gaccatccgg tgccagtgcc gatgcttcga tgacggcaac atcaatgtcg ccgaagaaac
    17401 cgtaattgac catttgcgcc acttcgctca aatgcaggtc aacgaaactc accgcgccct
    17461 gattgatctt tttacgtaaa ccggacgatg tttgatatgg cgcacgccag gaaacagcat
    17521 cggcgtcaga aagtacatcg tcagcggcgg cgctgattga cgcccccgtc agcaggcgaa
    17581 tttgatacgg ctttttggcc tcatgctgtt cgttagctct gcgggcaatc gcggtcggta
    17641 aggctttcgg cgaacccgct ggggtaaagc cgctaaatgc caccatgtcg ttatgctgga
    17701 taatttctgc cgcttcatcg gcggtcatcc ttgtccactg agtttccatt tttactcctt
    17761 cgttcgcagg gattaatgac caacgaaatt aggtttacgt ttttcgagga aagcgttcat
    17821 cccttcctgg taatcttcgc tgtcataaac cgcgcggcgc atcccctgaa tacgttcaaa
    17881 ttcatcggag ttcatggtgt gcgcttcgcc cagtacacgc agctcttctt tgataacagc
    17941 aatggctaac ggcgctttct cagagatgtg gtgcgccatt tgtaaggtga aatcttccag
    18001 ttcttccact tccacaacat ggttgaggat gccgacagcc aacgcgcgct gggcggtgat
    18061 tggcgaagcg gtaaaaatca gttctttgac aatgtggaag cccgcgtcgc gggtcaggtt
    18121 gtgaatgccg accaggttat acgggacgcc gaggtttaca ggcgtcattg agaaggttga
    18181 ggtactggcg gcgataatca gatcggaact catgatcatt tcaaatgcgc caccccaaac
    18241 actaccttcc accatcgaaa tgatcggttt cgggaatttt tggatcatgc gggtgatttg
    18301 acgcaatgga tcatcatagg agagtggatc gcgaccgcca gacggcagtt cgtgaatagc
    18361 gtggcctgcg gagaagactt tggatccact cggcgcgcgc aaaatgatac agcgaatttc
    18421 cggccggttg agatcgctta atgcctgcat aagatcatca ataaagactt tacttaaggc
    18481 attaagtttg cggccatagt taaactcaat gaccgccact ttgttgatag tgacaacgtt
    18541 aacatactga taagacataa aaattccttt aatcaaaata ttgcgtctgg ataaattcac
    18601 tgagctgccg caggccggtg cgcggtgaga gcgtattgtt tttgaccgct aaaagcgtct
    18661 ggcggtaata gcgatcgaaa tcttcattcg cgaacaggtg attcagtact tcttcttcgg
    18721 tctgcttacg cagccattcc accgattgtt gttgccgcac ttgttgtaaa cgaccactgg
    18781 cagttagcgc ggttttgaag tcgatgatgg cgtgccagat ctcatcgatt ccacgttttt
    18841 ccagtgcgct acaagtcaga acccgtggct gccattcgtc gtatttacgt cgcagaatat
    18901 gcagggcact ctcgtacata tgccgggcaa tggcgacatt ggtatggtta tcgccatcgt
    18961 ctttgttgat aacgatcaga tcagccactt ccatcagccc ttttttaatg ccctgcagat
    19021 catcgccgcc accggcaatt tgcaacgaga taaaacagtc caccatgcgg gcgacttctg
    19081 tttccgactg cccgacgcca accgtttcga caatcactac gtcataaccc gctgcttcgc
    19141 ataacagcat taattcccgc gctcgctgac tggcaccgcc cagatgaccg gaggatggta
    19201 ccgggcgaat aaacgccgct tcggcacgcg ccaggtcatt catgcgggtt ttatccccga
    19261 gaatgctacc gccagtgacc gggctgctgg gatcgaccgc aataaccgcg acctttaatc
    19321 cctctcgaat caacaacatg ccaaaggcct caagaaaggt acttttcccc gcgccggggg
    19381 tgccggtaac gcccagtcgc agggtgttac cgcagtacgg cataatggca tcaagcagct
    19441 gcgtacttag tgcctgatga cgcgggtgac ggctttccac cagcgtcatg gcctgggcga
    19501 gtgtggcacg ctcaccctga cgtaagcggc gaatactttc tgccagcgtg gcttcattaa
    19561 tcatgatgct ggcttatcag attcagtacg tcgcgcacac tgtcgagcat aggtgtacct
    19621 ggaccataaa tcgccgccac gccgcgctct tgcaggaagg cgtaatcctg cggcggaatg
    19681 acgccacccg cgaccacgca gatatcttcg cgtccccatt ttttcagcgc ttcgaccagt
    19741 tccgggatca gcgttttatg accggcagcc agtgaggatg cgcccactac gtgaacgtcg
    19801 ttttctacgg ccaggcgggc gatctcttca ggtgtagaga acatcgggct taaatctacg
    19861 tcgaaaccga gatcggaata ggcgctggcg atcactttcg cgccgcgatc gtgtccatcc
    19921 tggcccatct tagcgatcag aatgcgcggg cgacgaccat tgtcggcaag gaactgctcc
    19981 atttgcgcaa caatggcatc gaactcggag gccgatttct cagactgatg atagctttgc
    20041 gcaatcacgc cggtaacaca ctggcttggc accagataac ggtcgaaagc gacttccagc
    20101 gcatcggaaa tttcacccag ggtggcgcga acgcgagcgg cattaacagc ggcagccagc
    20161 aggttttcgt tatgctgtgc ggcgtgagtc agggcgttca acgcggcggt tacggcggca
    20221 tcatcacggg tggcgcgaat gcgttccagc gaagcaattt gctcgttacg caccatcacg
    20281 ttgtcgatct caagtacatc ggtttcgtct tcgtgatcca gtttgtactt gttgacacca
    20341 acgatgacac gcttgccctg gtcgatcagc gactgttcgc gcgctgaggc ctcttcgatc
    20401 attcgttttg gcagacctgc ttcgatcgct ttcgccatgc caccggcttc gtcgatctgt
    20461 tggataatag ctctggcttg tttgacgatt tgatcggtca gcgactcaat gtaataggat
    20521 ccggccagtg gatcgacgat gcggcagagt tctgattctt cctggatgat gatctgggtg
    20581 ttgcgggcaa tgcgtgctga gaaatcggta ggcaaaccaa gcgcttcgtc aaaggcgttg
    20641 gtatgcagtg actgagtacc gcccagcgtc gcagccagcg cttcaatggt ggtgcggata
    20701 acgttgttat acggatcctg ttcagtcagg ctccagcctg aggtctggca gtgggtacgc
    20761 agcgccagtg atttcgggtc ctgtgcgcca aatccactga ccgcttcgct ccataaataa
    20821 cgtgccgcac gcaacatggc gacgttcata aacagatcca tgccgatgcc gaagaagaac
    20881 gacaggcgag gagcgaagtc atcaattttc agtccggcag agattgctgc tttgatgtac
    20941 tcaatcccat cagcgagcgt aaatgctacc tgctgcacgc agttggcacc cgcttcaccc
    21001 atgtggtaac cgctgatact gatggtatta aatcgcggca tgttgccgga acaccaggcg
    21061 atgatgtcgg cgataatgcg cattgacggt tttggcgggt aaatataggt gttgcggcag
    21121 aggtactctt tgaggatatc gttctgaatg gtgccggtca gtttatcagg tgtaacacct
    21181 tgctcttccg cggcgatgat ataaaacgcc agtactggta gcactgcgcc attcatggtc
    21241 atcgaaaccg acattttatc cagcgggatc tggtcgaaca ggactttcat atcttccacg
    21301 gtgtcgatag cgacgcccgc tttgccgacg tcacccgcca cgcgtgggtt atcggagtcg
    21361 tagccacggt gggtggcaag gtcaaacgca acggaaagac ctttttgccc ggcggccagg
    21421 ttacggcgat aaaaagcgtt ggactctttt gctgttgaaa aaccagcata ctgacggatg
    21481 gtccacggtt gggcggtata catagtggca cgcgggccac gaacgtaggg cggcaaacca
    21541 ggaagggtac ctgtcacctc cagattatcg agatcggctt cggtatacag cggcttgatg
    21601 gcgatccctt ccgcggtttg ctgaaccagc gagtcgacag ttttctcccg acggctcaat
    21661 tccttgttgg caagctgttg ccactcctgc tcgttagaca ttatttgctc cgtaaaacgc
    21721 aatcaaaatg agggtatttg cgcttacggt gagcttttta cgtgggtttg tcgccagcaa
    21781 aaaaaatgca ttcagacgtc gttttttgcc gcctgagatt tgtctatttt gtgatgtgat
    21841 tcaaggaata caaaaagaag tgaggataac gcctgatatg tgctatcagg cattatttga
    21901 tggattaatc ctgacgaagg actttgtgac cataatcgag caacgcatca gtgactttac
    21961 gcatcatgcg gctttcagga gcaaagcggt gccagtagag catccggcgt tgaaatagcc
    22021 ctggcgttaa gtcaatcagt tcaccgctgg ctagttcttt ctcgatttgc aggtgcggga
    22081 tcatacagca ggtggtgccc tggcgagcaa gttgcacgaa cgcttctgaa gaattaacga
    22141 tatggcaggg cacgctgcct ggaggcagat cgaagttttg ctgcaaaaag gcctggtgca
    22201 tatcgtcaag atggtcaaag gcgaccacag gtgctttcaa taatgccgaa cgcgttacgc
    22261 cgttagggaa atatttttcg gcaaagggtt ttgagctgac gaacagatag tcgagcgcac
    22321 caagtttatc gacaagacaa ctcggcagcg cctgatgttg aatactcacc gcgccgacca
    22381 cttcgccgcg gcgcagacgt tcctgagtgc gggtttcatc ttctacctgc aagttgaggc
    22441 ggataggcga atcagccaac acaggagcca gtgcaggaag caaccacgtc gccagactgt
    22501 cggcgttgac cgccagtgaa agcagcagcg gagtcgaacc ggtttgttca tcgcccagcc
    22561 actcttcttc cagcaactcc acctggcgca gcagtgccag cagtttttgc ccttgttccg
    22621 tcgggcgcgg cggtacggta cgcaccaaca gcggctgccc gaacatattt tccagttgct
    22681 taatgcgctg tgagacggct gattgtgtaa tgcacagctt ttgtgccgcg cgctcaaatc
    22741 ctcgttcacg tatcaccgca tccagtgcct gtaatgttct gtagtccggg cgtttcattg
    22801 ctgttgtctg ctcctggtaa atgctttttc ctgcactatg acacaatttt gtgtcaggtt
    22861 gcatataccg aagccgtcgg cgggtaacat ttgtattcgt ggttaaacgc gcagcttaaa
    22921 agatcaggga tttgcgctaa tgcatttcgc tcagcgagtt cgcgccctgg ttgtgttgaa
    22981 tggcgtggcg ttattgcctc tgttcgcacc gtggagcggc atacccagac cgttgtatgc
    23041 tttatttgcg gggcgaaagg ggatgcccgc cattgcgcga tattttatgg atgagttaac
    23101 cacgcggctt gccaacgggg tctgaatcgc tttttttgta tataatgcgt gtgaaatttc
    23161 ataccacagg cgaaacgatc atgacgcagg atgaattgaa aaaagcagta ggatgggcgg
    23221 cacttcagta tgttcagccc ggcaccattg ttggtgtagg tacaggttcc accgccgcac
    23281 actttattga cgcgctcggt acaatgaaag gccagattga aggggccgtt tccagttcag
    23341 atgcttccac tgaaaaactg aaaagcctcg gcattcacgt ttttgatctc aacgaagtcg
    23401 acagccttgg catctacgtt gatggcgcag atgaaatcaa cggccacatg caaatgatca
    23461 aaggcggcgg cgcggcgctg acccgtgaaa aaatcattgc ttcggttgca gaaaaattta
    23521 tctgtattgc agacgcttcc aagcaggttg atattctggg taaattcccg ctgccagtag
    23581 aagttatccc gatggcacgt agtgcagtgg cgcgccagct ggtgaaactg ggcggtcgtc
    23641 cggaataccg tcagggcgtg gtgaccgata atggcaacgt gatcctcgac gtccacggca
    23701 tggaaatcct tgacccgata gcgatggaaa acgccataaa tgcgattcct ggtgtggtga
    23761 ctgttggctt gtttgctaac cgtggcgcgg acgttgcgct gattggcaca cctgacggtg
    23821 tcaaaaccat tgtgaaatga tctgacgggg gaacctcccc cgttaaaaaa attctcttca
    23881 ttaaatttgg tgacatgtgt cacgttttta cctggctatt gtcgattgct ctaaataaat
    23941 cttctaaacc agcatattca tccaagaatt acctttgcgt gatatttcct caacatcgcg
    24001 acgcaaacgt tcatattgcc gcaatattat tttttgatat gttgaaaggc ggacgcaaat
    24061 ccgcacacaa catttcaaaa gacaggattg ggtaaatggc aaaggtatcg ctggagaaag
    24121 acaagattaa gtttctgctg gtagaaggcg tgcaccaaaa ggcgctggaa agccttcgtg
    24181 cagctggtta caccaacatc gaatttcaca aaggcgcgct ggatgatgaa caattaaaag
    24241 aatccatccg cgatgcccac ttcatcggcc tgcgatcccg tacccatctg actgaagacg
    24301 tgatcaacgc cgcagaaaaa ctggtcgcta ttggctgttt ctgtatcgga acaaaccagg
    24361 ttgatctgga tgcggcggca aagcgcggga tcccggtatt taacgcaccg ttctcaaata
    24421 cgcgctctgt tgcggagctg gtgattggcg aactgctgct gctattgcgc ggcgtgccgg
    24481 aagccaatgc taaagcgcac cgtggcgtgt ggaacaaact ggcggcgggt tcttttgaag
    24541 cgcgcggcaa aaagctgggt atcatcggct acggtcatat tggtacgcaa ttgggcattc
    24601 tggctgaatc gctgggaatg tatgtttact tttatgatat tgaaaataaa ctgccgctgg
    24661 gcaacgccac tcaggtacag catctttctg acctgctgaa tatgagcgat gtggtgagtc
    24721 tgcatgtacc agagaatccg tccaccaaaa atatgatggg cgcgaaagaa atttcactaa
    24781 tgaagcccgg ctcgctgctg attaatgctt cgcgcggtac tgtggtggat attccggcgc
    24841 tgtgtgatgc gctggcgagc aaacatctgg cgggggcggc aatcgacgta ttcccgacgg
    24901 aacctgcgac caatagcgat ccatttacct ctccgctgtg tgaattcgac aacgtccttc
    24961 tgacgccaca cattggcggt tcgactcagg aagcgcagga gaatatcggc ctggaagttg
    25021 cgggtaaatt gatcaagtat tctgacaatg gctcaacgct ctctgcggtg aacttcccgg
    25081 aagtctcgct gccactgcat ggtggtcgtc gtctgatgca catccacgaa aaccgtccgg
    25141 gcgtgctaac tgcgctgaac aaaatcttcg ccgagcaggg cgtcaacatc gccgcgcaat
    25201 atttacaaac ttccgcccag atgggttatg tagttattga tattgaagct gacgaagacg
    25261 ttgccgaaaa agcgctgcag gcaatgaaag ctattccggg taccattcgc gcccgtctgc
    25321 tgtactaatt ccccttctct gaaaattaac gggcaggtca ctgacttgcc cgttttttta
    25381 tcccttctcc acaccgttgc cgcgttgcgc attctacttt gcgagtctgc tccagaaaat
    25441 aaatcaaagt cagatcaatg cgttgtgttt atttaatggg gatttacgat ggcgggacag
    25501 catggggctg taacggtaaa gccctcaccg aagcgagggc ttaaaggaga agggttatga
    25561 tgcgacttgt catcatactg attgtactgt tactgataag tttcggagct tattaacagt
    25621 cagtctcagg ggaggagtca tcctccctta cccttactca ctaaattagg tcaaagaatc
    25681 aacgatgtca atcagggcga tgcggggtgc atcgccctga accgaacttt ttgatagcca
    25741 cttcatcgcc cacgtttact gccgtaatag atcctttttc ccaaaaatta tctctgtttt
    25801 gcatggggtt tttcgagcac gctcgaagaa aagatttaaa ggtagatcaa tgcgttgtgg
    25861 ttatttaaag agagcttacg atagctgggc agcatggggc tgtaacggta aagccctcac
    25921 cgaagcgagg gcttgaagga gaagggttat gatgcgactt gccatcatac tgattgtact
    25981 gttactcata agtttcccag cttattaaca gtcagtcaca ggggaggagc aatcctccct
    26041 tacccttact cactaaatta ggttaaagaa tcaacgatgt caatcagggc gatgcaggtg
    26101 tatcgccctt accactccca gactttcgac ggtgtaacca ccgcaggaag agggatatcc
    26161 cactcttcaa cggggagttt ttccaccaac tgacaatcat gcgcataacc caccggttgc
    26221 gttttatagt gctgccagtt ttgtaaggtc cgatcataaa aaccaccgcc cattcccagg
    26281 cgctgaccgt actcatcaaa ggcgaccagc ggtgtgatca gcacgtctaa tcgggaaagg
    26341 ggtagcacgt cacgcacatc cagttttggc tcatggatct tcaacctgtt catcaccagt
    26401 tcgctttgcg gatggtaatt caggaacagc aaattaccgg cactaaaggg atgcaaaact
    26461 ggaagatata cgcgcttacc ggcgcgccag agttgttcta ttagcggctg ggtgtcgagt
    26521 tcaccatcaa aagagaggaa tacagcgacc gtatgcgcca tcaccaccgg gggataagtc
    26581 atcatccggg tagcggcttg ttgacccatt tcctgctgtt gttccggcgt taacgcacga
    26641 cgacgttgcc gaatcatttt gcggatttct tgtcgggata atgtcagtgg gagttctggt
    26701 agttgcgtca tggctggtgc cagataagaa gggaatctcc gagatgccgc cgcaggctgt
    26761 aacccttgaa cccttggttc aaggtgaatg tgtcgtcgca gttttaaggc ttctcggacg
    26821 gaccgagcat gctcaccaac cgcggagcgc cacattcttg tggtatgaaa tatcggctca
    26881 ggggactggc ccgcttgcga acatctcaga gaaattttgt cttcacggtt actctaccac
    26941 agtaaaccga aaagtgtcat tcaaagtttt ggttagtttt ttcggtgatg cgaccttgtt
    27001 caagtaacgc ttgttctatg gtctgctgca gcatccgaat acgctgttcc atacttgccg
    27061 cgtagtcacg agtcttcgct ttttcttgcg ctaactcata gctgatattc aatgcggcaa
    27121 tgaagaccaa ctgttcagta tttgtgactc tagtgcgttc tttcagatct tgcaaccgtt
    27181 ggttcagatc gtccgctgcc tgattcaacg catccctttg gtcaggcggg cagttcacac
    27241 gcagtgaacg gccaaaaatt tggatatcga cgggttgtgc agacatgcca ccttcctgct
    27301 gattgactgc gctgccttcg tctttagacc catggtctgc gaaggggcga cactatagct
    27361 accctgatga gaagagacaa gcccttttct ggtccaccag ggcccaaagt ggtagcatat
    27421 catgaatatt cctccctttg acgacgaatg cttatgtcta tacagaacga aatgcctggt
    27481 tacaacgaaa tgaaccagta tctgaaccaa caagggacgg gtctgacccc tgctgagatg
    27541 catggtttaa tcagtgggat gatatgtggc ggtaacgatg acagctcatg gctaccgcta
    27601 cttcacgacc tgacgaacga aggcatggct ttcggtcatg agctggcaca ggcactgcgt
    27661 aaaatgcact ctgccaccag cgatgccctg caggatgacg gcttcctttt tcagctttat
    27721 ctgcctgatg gcgatgatgt cagcgttttc gatcgggctg atgcattggc aggttgggtc
    27781 aatcacttcc tgcttggtct tggcgttacg caaccgaagc tggataaagt gaccggcgaa
    27841 accggtgaag ctatcgacga tctgcgtaac attgcgcaac tgggttacga cgaagacgaa
    27901 gatcaggaag agcttgaaat gtcgcttgaa gagatcatcg aatacgttcg tgttgccgcg
    27961 ctgttatgcc acgacacctt tactcatccg caaccgaccg cgccagaagt acaaaaaccg
    28021 actctacact aaaaacaaaa aacgtaagga gagtgttatg agtgagatat cccggcaaga
    28081 gtttcagcgt cgccgtcagg ccctggtgga gcaaatgcaa cccggcagcg ccgcgctgat
    28141 ttttgctgca ccagaagtaa cacgtagcgc cgacagcgaa tacccctatc gtcagaacag
    28201 tgacttctgg tacttcaccg gctttaacga accggaagcg gtgctggtgc tgattaaaag
    28261 cgatgacact cataaccaca gcgttctgtt taaccgcgtt cgcgacctga cggcggagat
    28321 ctggtttggc cgtcgcttag gccaggatgc cgcgccagag aaactgggcg ttgaccgcgc
    28381 actggcattc agcgaaatca atcagcaact ttatcaacta cttaacggcc tggatgtggt
    28441 ttaccatgcc cagggcgaat atacctatgc tgatgaaatc gtgaacagtg cgctggaaaa
    28501 actgcgtaaa ggttcgcggc aaaatctcac cgcaccggca acgatgatcg actggcgtcc
    28561 tgttgttcat gaaatgcgcc tgttcaaatc gccagaagag attgccgtac tccgccgcgc
    28621 gggagaaatc accgccatgg cacatacacg ggcgatggaa aaatgccgtc cgggaatgtt
    28681 cgagtaccat ctggaaggcg aaattcacca cgaatttaac cgccacggtg cgcgctatcc
    28741 gtcctataac accattgtcg gcagcggtga aaacggctgc attctgcact acaccgaaaa
    28801 cgagagtgaa ctgcgcgacg gtgacctggt gttgattgac gcgggttgtg aatacaaagg
    28861 ttacgcgggc gatattaccc gcaccttccc ggtcaacggc aaattcaccc aggcccagcg
    28921 tgaaatctac gacattgtgc tggagtctct cgaaaccagc ctgcgcctgt atcgtccggg
    28981 aacttccatt ctggaagtca ctggtgaagt ggtgcgcatc atggttagcg gcctggtaaa
    29041 actcggcatc ctgaaaggtg atgttgatga actgatcgct cagaacgccc atcgtccttt
    29101 ctttatgcat ggccttagcc actggttagg actggatgtc catgacgttg gcgtttatgg
    29161 tcaggatcgc tcgcgcattc tggaaccggg gatggtactg accgtagagc ctggtctgta
    29221 tatcgcgccg gatgcggatg tgccagaaca atatcgcggt atcggcattc gaattgaaga
    29281 cgacattgtg attaccgaaa ccggtaacga aaacctcacc gccagcgtgg tgaaaaagcc
    29341 ggaagaaatc gaagcgttga tggctgctgc gagaaagcaa tgagcgtaat catcgtcggt
    29401 ggcggcatgg cgggcgcgac gctggcgctg gctatttccc ggttaagtca cggggcgctg
    29461 ccggtacatt tgattgaagc gactgcgcca gagtcacatg ctcatccggg ctttgatgga
    29521 cgagcgatag cgctggcggc gggtacctgt cagcaactgg cgcgcatcgg cgtctggcaa
    29581 tctctggcgg attgcgcaac tgccatcacc accgtgcatg tcagcgatcg tggtcacgct
    29641 ggatttgtca ccctcgccgc agaagattac caactggcgg cgctgggaca ggttgtcgaa
    29701 ttgcacaatg tcgggcaacg gctgtttgca ttgctgcgta aagcacctgg cgtaatgctg
    29761 cattgccccg atcgcgtagc taacgttgcc cgtactcaga gtcacgttga agtgacgctg
    29821 gagagtggcg agacgctgac gggccgcgtg ctgatagccg ctgatggcac ccattcagcg
    29881 ttagccaccg cgtgcggcgt tgactggcag caggagcctt acgaacaact ggccgtgatt
    29941 gccaacgttg cgacttccgt tgcgcacgaa ggccgcgctt ttgaacgctt cacgcaacat
    30001 ggcccgctgg cgatgttgcc gatgtctgac ggacgctgtt cgctggtctg gtgtcatcca
    30061 ctggaacggc gcgaagaggt gctgtcgtgg agcgacgaga agttttgccg tgaactccag
    30121 tcggcctttg gctggcgact tggaaaaatt acccacgccg gtaaacgcag tgcttatccg
    30181 ctggcgttaa cccgcgccgc cagagctatt acccatcgta ccgtgctggt gggcaatgcg
    30241 gcgcaaactc tgcacccgat tgccgggcaa gggtttaacc tcggtatgcg agatgtcatg
    30301 agccttgcgg aaaccctgac tcaggcgcat gagcgcggag aagacatcgg tgattacggc
    30361 atattgtgcc gctatcagca gcgtcgacag agcgatcgcg aagcaaccat cggcgtcacg
    30421 gacagcctgg tacatctttt tgccaaccgt tgggcaccgc tggttgtcgg gcgcaacatc
    30481 ggactgatga cgatggaatt attcaccccg gcacgcgatg tgctggcgca gcgcaccctc
    30541 ggttgggtgg cgcgttgaag gcggttttaa ggaataaaca atgcaaagtg ttgatgtagc
    30601 cattgttggt ggcggcatgg tggggctggc ggttgcctgc ggcttacagg ggagcggctt
    30661 acgcgttgcc gtactggagc agcgcgtacc ggaacctctg gtggcggatg caccaccaca
    30721 actgcgcgtt tcggctatca atgccgccag cgaaaaatta ctcacccgtc ttggcgtctg
    30781 gcaggacatt ctctctcgta gggccagttg ttatcacggt atggaagtgt gggacaaaga
    30841 cagttttggt cacatttcgt ttgacgatca aagcatgggc tatagccatc ttgggcatat
    30901 cgttgaaaac tcagtgattc actacgcgct gtggaacaaa gcgcagcagt cgtcagatat
    30961 cactctgttg gcccccgcag aattacagca ggtcgcctgg ggagaaaatg aaactttcct
    31021 gacgctgaaa gatggcagca tgttaacggc gcgtctggtg attggcgcgg acggtgctaa
    31081 ttcctggttg cgcaacaaag cagatattcc gctgactttc tgggattatc agcatcacgc
    31141 gctggtagcg accattcgca cggaagaacc gcatgatgcg gtggcgcggc aggttttcca
    31201 tggcgaaggc attctggcct ttttaccgct tagcgatccg catctttgct caattgtctg
    31261 gtcactgtcg ccagaggaag cgcagcggat gcagcaggca agtgaagatg aatttaatcg
    31321 cgcgttaaat atcgcttttg ataatcgcct gggcttatgc aaggttgaga gcgcgcgtca
    31381 ggtgttccca ctgacggggc gttatgcgcg ccagtttgcc gcgcaccgtc tggtgctggt
    31441 gggcgacgcc gcgcatacca ttcacccgct ggcggggcag ggagtaaatc tcggctttat
    31501 ggatgctgca gagctgattg ctgaactgaa acggttgcat cgtcagggga aagacatcgg
    31561 gcagtacatt tacctgcgcc ggtatgagcg tagccgcaag cacagtgcgg cgctgatgct
    31621 ggctggtatg cagggattcc gcgatctgtt ttccggtacc aatccggcga aaaaactgct
    31681 gcgtgatatt ggtttgaaac tggccgacac gcttcctggc gttaaaccac aacttatccg
    31741 ccaggcaatg ggattaaacg atttgcctga atggctgcgt taaaaatttc tcttctgctg
    31801 tttatttgat acccatcaca ctttcatctc ccggtttttt cgccgggaga ttttcctcat
    31861 ttgaaataaa ctaatttcac ctccgttttc gcattatatt ttctaatgtc attatttttt
    31921 gatttagtgt tttttgacat ttttttagct cttaatattg ccttattcaa attagctttc
    31981 taatggcatc atctttatat agaaactggt gtgttttttg gttttttatt ctgtcgcgat
    32041 tttggcgttt tttaaccata agctaatgtg atgatcaatt ttaccttatg gttaacagtc
    32101 tgtttcggtg gtaagttcag gcaaaagaga acgattgcgt tggggaccgg gagtggctcc
    32161 gatgctgggt ttcgtggtga taatttcacc atgaaaagtt gtcagccccg cttattcaat
    32221 gaggacaaga tggcacaaca gactcctttg tacgaacaac acacgctttg cggcgctcgc
    32281 atggtggatt tccacggctg gatgatgccg ctacattacg gttcgcaaat cgacgaacat
    32341 catgcggtac gtaccgatgc cggaatgttt gatgtgtcac atatgaccat cgtcgatctc
    32401 cgcggcagcc gcacccggga gtttctgcgt tatctgctgg cgaacgatgt ggcgaagctc
    32461 accaaaagcg gcaaagccct ttactcgggg atgttgaatg cctctggcgg tgtgatagat
    32521 gacctcatcg tctactactt tactgaagat ttcttccgcc tcgttgttaa ctccgccacc
    32581 cgcgaaaaag acctctcctg gattacccaa cacgctgaac ctttcggcat cgaaattacc
    32641 gttcgtgatg acctttccat gattgccgtg caagggccga atgcgcaggc aaaagctgcc
    32701 acactgttta atgacgccca gcgtcaggcg gtggaaggga tgaaaccgtt ctttggcgtg
    32761 caggcgggcg atctgtttat tgccaccact ggttataccg gtgaagcggg ctatgaaatt
    32821 gcgctgccca atgaaaaagc ggccgatttc tggcgtgcgc tggtggaagc gggtgttaag
    32881 ccatgtggct tgggcgcgcg tgacacgctg cgtctggaag cgggcatgaa tctttatggt
    32941 caggagatgg acgaaactat ttctccttta gccgccaaca tgggctggac tatcgcctgg
    33001 gaaccggcag atcgtgactt tatcggtcgt gaagccctgg aagtgcagcg tgagcatggt
    33061 acagaaaaac tggttggtct ggtgatgacc gaaaaaggcg tgctgcgtaa tgaactgccg
    33121 gtacgtttta ccgatgcgca gggcaaccag catgaaggca ttatcaccag cgggactttc
    33181 tccccgacgc tgggttacag cattgcgctg gcacgcgtgc cggaaggtat tggcgaaacg
    33241 gcgattgtgc aaattcgcaa ccgtgaaatg ccggttaaag tgacgaaacc tgtttttgtg
    33301 cgtaacggta aagccgtcgc gtgatttact tttttggaga ttgattgatg agcaacgtac
    33361 cagcagaact gaaatacagc aaagaacacg aatggctgcg taaagaagcc gacggcactt
    33421 tcaccgttgg tataaccgaa catgcccagg agctgttagg cgatatggtg tttgttgacc
    33481 tgccggaagt gggcgcaacg gttagcgcgg gcgatgactg cgcggttgcc gaatcagtaa
    33541 aagcggcgtc agacatttat gcgccagtaa gcggtgaaat cgtggcggta aacgacgcac
    33601 tgagcgattc cccggaactg gtgaacagcg aaccgtatgc aggtggctgg atctttaaaa
    33661 tcaaagccag cgatgaaagc gaactggaat cactgctgga tgcgaccgca tacgaagcat
    33721 tgttagaaga cgagtaacgg ctttattcct cttctgcggg agaggatcag ggtgaggaaa
    33781 atttatgcct caccctcact ctcttcgtaa ggagagaggt tcacaattca ctgcacgttt
    33841 caggaaccat cgctcatgac acagacgtta agccagcttg aaaacagcgg cgcttttatt
    33901 gaacgccata tcggaccgga cgccgcgcaa cagcaagaaa tgctgaatgc cgttggtgca
    33961 caatcgttaa acgcgctgac cggccagatt gtgccgaaag atattcagct tgcgaccccg
    34021 ccgcaggttg gcgcaccggc gaccgaatac gccgcactgg cagaactcaa ggctattgcc
    34081 agtcgcaata aacgcttcac gtcttacatc ggcatgggtt acaccgccgt gcagctaccg
    34141 ccggttatcc tgcgtaacat gctggaaaat ccgggctggt ataccgcgta cactccgtat
    34201 caacctgaag tctcccaggg ccgccttgaa gcactgctca acttccagca ggtaacgctg
    34261 gatttgactg gactggatat ggcctctgct tctcttctgg acgaggccac cgctgccgcc
    34321 gaagcaatgg cgatggcgaa acgcgtcagc aaactgaaaa atgccaaccg cttcttcgtg
    34381 gcttccgatg tgcatccgca aacgctggat gtggtccgta ctcgtgccga aacctttggt
    34441 tttgaagtga ttgtcgatga cgcgcaaaaa gtgctcgacc atcaggacgt cttcggcgtg
    34501 ctgttacagc aggttggcac aaccggtgaa atccacgact acaccgcgct tattagcgaa
    34561 ctgaaatcac gcaaaattgt ggtcagtgtc gccgccgata ttatggcgct ggtgctgtta
    34621 actgcgccgg gtaaacaggg cgcggatatt gtttttggtt cggcgcaacg cttcggcgtg
    34681 ccgatgggct acggtggccc acacgcggcc ttctttgcgg cgaaagatga atacaaacgc
    34741 tcaatgccgg gccgtattat cggtgtatcg aaagatgcag ctggcaatac cgcgctgcgc
    34801 atggcgatgc agactcgcga gcaacatatt cgccgtgaga aagcgaactc caacatttgt
    34861 acttcccagg tgctgctggc aaacatcgcc agcctgtatg ccgtttatca cggcccgatt
    34921 ggcctgaaac gtatcgctaa ccgcattcac cgtctgaccg atatcctggc ggcgggcctg
    34981 caacaaaaag gtctgaaact gcgccatgcg cactatttcg acaccttgtg tgtggaagtg
    35041 gccgacaaag cgggcgtact gacgcgtgcc gaagcggctg aaatcaacct gcgtagcgat
    35101 attctgaacg cggttgggat cacccttgat gaaacaacca cgcgtgaaaa cgtaatgcag
    35161 cttttcaacg tgctgctggg cgataaccac ggcctggaca tcgacacgct ggacaaagac
    35221 gtggctcacg acagccgctc tatccagcct gcgatgctgc gcgacgacga aatcctcacc
    35281 catccggtgt ttaatcgcta ccacagcgaa accgaaatga tgcgctatat gcactcgctg
    35341 gagcgtaaag atctggcgct gaatcaggcg atgatcccgc tgggttcctg caccatgaaa
    35401 ctgaacgccg ccgccgagat gatcccaatc acctggccgg aatttgccga actgcacccg
    35461 ttttgtccgc cggaacaggc tgaaggttat cagcagatga ttgcgcagct ggctgactgg
    35521 ctggtgaaac tgaccggtta cgacgccgtt tgtatgcagc cgaactccgg cgcacagggc
    35581 gaatacgcgg gcctgctggc gattcgtcat tatcatgaaa gccgcaacga agggcatcgc
    35641 gatatctgcc tgatcccggc ttctgcgcac ggaactaacc ccgcttctgc acatatggca
    35701 ggaatgcagg tggtggttgt ggcgtgtgat aaaaacggca acatcgatct gactgatctg
    35761 cgcgcgaaag cggaacaggc gggcgataac ctctcctgta tcatggtgac ttatccttct
    35821 acccacggcg tgtatgaaga aacgatccgt gaagtgtgtg aagtcgtgca tcagttcggc
    35881 ggtcaggttt accttgatgg cgcgaacatg aacgcccagg ttggcatcac ctcgccgggc
    35941 tttattggcg cggacgtttc gcacctcaac ctgcataaaa ctttctgcat tccgcacggc
    36001 ggtggtggtc cgggtatggg accgatcggt gtgaaagcgc atctggcacc gtttgtaccg
    36061 ggtcatagcg tggtgcaaat cgaaggcatg ttaacccgtc agggcgcagt ttctgcggca
    36121 ccgttcggta gcgcctctat cctgccaatc agctggatgt acatccgcat gatgggcgca
    36181 gaagggctga aaaaagcaag ccaggtggca atcctcaacg ccaactatat tgccagccgc
    36241 ctgcaggatg ccttcccggt gctgtatacc ggtcgcgacg gtcgcgtggc gcacgaatgt
    36301 attctcgata ttcgcccgct gaaagaagaa accggcatca gcgagctgga tattgccaag
    36361 cgcctgatcg actacggttt ccacgcgccg accatgtcgt tcccggtggc gggtacgctg
    36421 atggttgaac cgactgaatc tgaaagcaaa gtggaactgg atcgctttat cgacgcgatg
    36481 ctggctatcc gcgcagaaat cgaccaggtt aaagccggtg tctggccgct ggaagataac
    36541 ccgctggtga acgcgccgca cattcagaac gaactggtcg ccgagtgggc gcatccgtac
    36601 agccgtgagg ttgcagtatt cccggcaggt gtggcagaca aatactggcc gacggtgaaa
    36661 cgtctggatg atgtttacgg cgaccgtaac ctgttctgct cctgcgtacc gattagcgaa
    36721 taccagtaat tcactgattc gactattttc taaaggcgct tcggcgcctt tttagtcaga
    36781 tgacaaagta caaaagtgct cagacagtcc cctcgcccct ttggggagag ggtgagggga
    36841 acaggccggc actggcgcga atatttaccc tcaccccggc cctctccctg aaagggcgag
    36901 ggggaaaagc gtgccaacat tgaagattga gccagtttgt tagcaatctc aaagatacgt
    36961 caacgaatga atttttctcg gaaaaacaaa tggttatagc acttgtgacc ggtggcagtc
    37021 gcggcatcgg gcgggcaact gcattactgt tggcgcaaga agggtatacg gtggcggtta
    37081 attatcagca aaacctccac gcggcgcagg aagtgatgaa cttaataacg caagccggtg
    37141 gcaaagcatt cgtgctccag gcggatatca gcgacgaaaa ccaggtcgtt gcgatgttta
    37201 cagcaatcga tcagcacgat gaaccgctag cagcgctggt caataacgcc gggatcttgt
    37261 ttacccagtg caccgttgaa aaccttaccg cagagcgaat caaccgagta ctttccacca
    37321 acgtgacggg atattttctc tgctgccgcg aggcggtaaa acgcatggcg cttaaaaatg
    37381 gtggcagtgg cggcgctatc gtcaatgtct cttcggtggc ctcacggttg ggttcgctag
    37441 gggaatatgt tgattacgcg gcatcgaaag gggcgattga tacgttaacc accggactat
    37501 cgctggaagt cgccgcgcag gggatccgcg ttaactgcgt gcggccaggg tttatttata
    37561 ccgaaatgca cgccagcggc ggcgagcctg gacgcgtcga tcgcgttaag tcgaacatcc
    37621 ccatgcagcg tggtggacag gcagaagagg tcgcgcaggc cattgtctgg ctactaagtg
    37681 ataaagcctc ttacgtcacg ggaagtttta tcgatttggc gggcgggaaa taaaacaggg
    37741 aagttgtctg accggatgca acaagtattg catccggtac ttcatcgact taaagcttct
    37801 cgccgttgct ggcaatcacc tcttggtacc agttaaagct cttcttacgt gaacgcgaca
    37861 tatcgccagc accgtcgtca tgtttattca catagataaa gccgtagcgt ttgctgtact
    37921 gcccggtggt gaacgatacg cagtcgatgc agccccacgg tgtgtagccc atcagatcca
    37981 cgccatcgta agtcaccgct tttttcatct cttcgatatg ggcgcgcagg tagtcaatgc
    38041 ggtagtcgtc gttgatgctg ccatcttctt ccactttgtc gtaagcgcca aaaccgtttt
    38101 cgacaataaa cagcggcctc tgataacgct catacagttc gcaaagggca tagcgcagac
    38161 ctactggatc aatctgccag ccccagtcag acgctttaac atacgggttc ggtacgctgc
    38221 cttcgaaacc agagatcgca tcgccggtgc cgccttcggc cttcactgcg ttggtcatgt
    38281 aatagctgaa accaagataa tcgcaggtgc cttcacgcag tacatcgaga tcgccgtctt
    38341 ccattttgat gttaaatccg cgacgctccc actcgttcaa cacataggac gggtaatagc
    38401 cgcgtagctg cacatcggta aagacgtagc gttcgcgcat cgactcctga gcgaacatca
    38461 catcgtccgg gttacagcag tagggataga gcggcaccat cgccagcata cagccgactt
    38521 tcatctccgg gttaatgcga cgcgcagctt tcaccgccag ggcgctggcg acaaactggt
    38581 gatgcagcac ctggtacatc gtctcttccg ggttgtcatg ctcggtataa accacgccgg
    38641 agcagcagta accgaacagc ggtgcacgcc agttacgctg gttgttaatt tcgttgaagg
    38701 tcatccagta tttgacttta tgcttatagc gttcaaacac cacttccgcg aaacggacaa
    38761 agaaatcaac cactttacgg ttggtccagc taccgtattg ctgcaccaga tgcagcggca
    38821 tttcaaagtg ggagagggtg atcaccggtt cgatgttgta tttcagcagt tcatcgaaca
    38881 tatcatcgta gaacttcagc ccttcttcgt ttggctgagc ttcatcacct tttggaaaaa
    38941 tacgcgtcca ggcgatggaa gtccgaaaac atttgaagcc catttcggca aatagcttga
    39001 tgtcttcctt gtagtgacca taaaaatcaa cggcttcatg gtttggatag tatttgcctg
    39061 gcaagacttc tttggtgatt tcgcgcggca cgccgtgtgc gccaccggtc agaacgtcac
    39121 aaatgctcgg ccctttgccg cctttgttcc agctgccttc gacctgatga gcggcaactg
    39181 cgccgcccca taagaaatct ttcggtaagg tgagtttttt cactatcata ggctccagat
    39241 gagtcaattc ttacaggaaa tagtaccatg cagccaaacg acatcacttt ttttcaacgt
    39301 ttccaggatg acattctggc tgggcgtaaa accatcacca tccgcgacga gtctgaatcg
    39361 cacttcaaaa cgggtgatgt gcttcgtgtc gggcgttttg aagatgacgg ttatttttgc
    39421 acgattgaag tcaccgcaac ctcaaccgta aggctggata cgctgactga aaaacatgca
    39481 gagcaggaaa atatgaccct gactgaactg aaaaaggtca ttgccgacat ctatcccggt
    39541 cagacacagt tttatgtgat tgaatttaaa tgtctttaaa ttgaactcac gcctgttagt
    39601 tgaaatttct catttaattt catgattttt aggagattag tctcaaatca gaatttattt
    39661 tagctaacag gtgttcactg gaactattct cagttacgct ggagaggtat acatgtgcgt
    39721 gtacgtttct ccggagtaag ttatggttca gaagcccctc attaagcagg gatattcgct
    39781 ggcagaggaa attgccaaca gcgtcagtca cggcattggg ttggtgtttg gtatcgttgg
    39841 gctggtgttg ctactggttc aggcggtgga tctcaatgcc agcgccacag cgataaccag
    39901 ctacagcctc tatggcggca gtatgatcct gctgttcctc gcttcgacgc tctatcacgc
    39961 cattcctcat caacgggcaa aaatgtggct gaagaaattt gaccattgcg ctatttacct
    40021 gttgattgcc ggaacctaca cgccgttttt gctggtgggg ctggattctc cgttagcgcg
    40081 cgggttgatg attgttatct ggagcctggc attgctgggg attctgttta aactgaccat
    40141 cgcgcaccga ttcaaaattt tatctctggt gacctatctg gcgatgggct ggctgtcgct
    40201 ggtggtaatt tatgaaatgg cagttaagct cgcggcgggc agcgttacct tactggcggt
    40261 aggcggcgtg gtttattcgc tcggggtgat tttctacgtc tgcaaacgca ttccatacaa
    40321 ccatgccatc tggcacggct tcgtgctcgg cggtagtgtg tgccactttc tggcgatcta
    40381 tttgtatatt gggcaggcgt aatgggtatg c
//
LOCUS       DAZUDJ010000042        40307 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.042, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000042 DAZUDJ010000000
VERSION     DAZUDJ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40307
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.042"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(312..524)
                     /gene="rpmE"
                     /locus_tag="ACHY1N_002942"
     CDS             complement(312..524)
                     /gene="rpmE"
                     /locus_tag="ACHY1N_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HFS4045224.1"
                     /translation="MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFF
                     TGKQRDVATGGRVDRFNKRFNIPGSK"
     gene            727..2925
                     /gene="priA"
                     /locus_tag="ACHY1N_002943"
     CDS             727..2925
                     /gene="priA"
                     /locus_tag="ACHY1N_002943"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709739.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFS4045225.1"
                     /translation="MPVAHVALPVPLPRTFDYLLPEGMTVKAGCRVRVPFGKQQERIG
                     VVVSVSDVSELPLNELKAVVEVLDVEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPI
                     LLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF
                     NDAALQALRKKGLCDLASETPEFSDWQTNYAVSGERLRLNTEQATAVGAIHSAADTFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVL
                     DLKGQKVQAGLAPALITRMRQHLQANNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQQHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPDVPIS
                     RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAE
                     RRMMQLPPWTSHVIVRAEDHNNQHAPLFLQQLRNLILSSPLADDKLWVLGPVPALAPK
                     RGGRWRWQILLQHPSRVRLQHIISGTLALINTIPDSRKVKWVLDVDPIEG"
     gene            3081..4106
                     /gene="cytR"
                     /locus_tag="ACHY1N_002944"
     CDS             3081..4106
                     /gene="cytR"
                     /locus_tag="ACHY1N_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HFS4045226.1"
                     /translation="MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRV
                     EKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLI
                     GDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
                     LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVD
                     PQYIARGDFTFEAGSKAMQQLLDLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLS
                     IIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHVGSGSRLMDCELIIR
                     GSTRALP"
     gene            4198..5157
                     /gene="ftsN"
                     /locus_tag="ACHY1N_002945"
     CDS             4198..5157
                     /gene="ftsN"
                     /locus_tag="ACHY1N_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HFS4045227.1"
                     /translation="MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVL
                     VTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEP
                     SAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
                     QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTT
                     AQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQADTVRAQLAFEGFDSK
                     ITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG"
     gene            5250..5780
                     /gene="hslV"
                     /locus_tag="ACHY1N_002946"
     CDS             5250..5780
                     /gene="hslV"
                     /locus_tag="ACHY1N_002946"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0051603 - proteolysis involved in protein
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HFS4045228.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDIC
                     IYTNHFHTIEELSYKA"
     gene            5790..7121
                     /gene="hslU"
                     /locus_tag="ACHY1N_002947"
     CDS             5790..7121
                     /gene="hslU"
                     /locus_tag="ACHY1N_002947"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HFS4045229.1"
                     /translation="MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFR
                     KKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKI
                     KDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGA
                     RRLHTVLERLMEEISYDASDLSGQTIIIDADYVSKHLDALVADEDLSRFIL"
     gene            7188..8114
                     /gene="menA"
                     /locus_tag="ACHY1N_002948"
     CDS             7188..8114
                     /gene="menA"
                     /locus_tag="ACHY1N_002948"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFS4045230.1"
                     /translation="MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPL
                     VALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALIIT
                     VVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVLV
                     FFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVV
                     RLGEVNARRYHACLLMGSLVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDP
                     VAMRPMLERTVKGALLTNLLFVLGIFLSQWAA"
     gene            8207..8692
                     /gene="rraA"
                     /locus_tag="ACHY1N_002949"
     CDS             8207..8692
                     /gene="rraA"
                     /locus_tag="ACHY1N_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008428 - ribonuclease inhibitor activity
                     [Evidence IEA];
                     GO_process: GO:0051252 - regulation of RNA metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HFS4045231.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(8777..9022)
                     /gene="zapB"
                     /locus_tag="ACHY1N_002950"
     CDS             complement(8777..9022)
                     /gene="zapB"
                     /locus_tag="ACHY1N_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HFS4045232.1"
                     /translation="MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQ
                     NAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV"
     gene            9447..10292
                     /gene="glpF"
                     /locus_tag="ACHY1N_002951"
     CDS             9447..10292
                     /gene="glpF"
                     /locus_tag="ACHY1N_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein GlpF"
                     /protein_id="HFS4045233.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAA
                     LVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAG
                     WGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSE
                     QKASL"
     gene            10315..11823
                     /gene="glpK"
                     /locus_tag="ACHY1N_002952"
     CDS             10315..11823
                     /gene="glpK"
                     /locus_tag="ACHY1N_002952"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFS4045234.1"
                     /translation="MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPG
                     WVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAI
                     VWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGE
                     LLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEV
                     RRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNT
                     GEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFA
                     TKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDV
                     LEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGL
                     AVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE"
     gene            11959..12969
                     /gene="glpX"
                     /locus_tag="ACHY1N_002953"
     CDS             11959..12969
                     /gene="glpX"
                     /locus_tag="ACHY1N_002953"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HFS4045235.1"
                     /translation="MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVT
                     ILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMNGRLLARHDVKGDNEENRRIGEQELARCKAMGIEAGKVLRLGDMARSD
                     NVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQSIHYLDRKDPEMQVH
                     IL"
     gene            13066..13812
                     /gene="fpr"
                     /locus_tag="ACHY1N_002954"
     CDS             13066..13812
                     /gene="fpr"
                     /locus_tag="ACHY1N_002954"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004324 - ferredoxin-NADP+ reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HFS4045236.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEID
                     GERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDE
                     VPDCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEK
                     RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESAIGLPMNKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(13817..14245)
                     /gene="uspD"
                     /locus_tag="ACHY1N_002955"
     CDS             complement(13817..14245)
                     /gene="uspD"
                     /locus_tag="ACHY1N_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspD"
                     /protein_id="HFS4045237.1"
                     /translation="MAYKHIGVAISGNEEDALLVNKALELARHNDAHLTLIHIDDGLS
                     ELYPGIYFPATEDILQLLKNKSDNKLYKLTKNIQWPKTKLRIERGEMPETLLEIMQKE
                     QCDLLVCGHHHSFINRLMPAYRGMINKMSADLLIVPFIDK"
     gene            complement(14272..14571)
                     /gene="yiiS"
                     /locus_tag="ACHY1N_002956"
     CDS             complement(14272..14571)
                     /gene="yiiS"
                     /locus_tag="ACHY1N_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF406 domain-containing protein"
                     /protein_id="HFS4045238.1"
                     /translation="MKDVVDKCSTKGCAIDIGTVIDNDNCTSKFSRFFATREEAESFM
                     TKLKELAAAASSADEGASVAYKIKDLEGQVELDAAFTFSCQAEMIIFELSLRSLA"
     gene            complement(14783..15223)
                     /gene="yiiR"
                     /locus_tag="ACHY1N_002957"
     CDS             complement(14783..15223)
                     /gene="yiiR"
                     /locus_tag="ACHY1N_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HFS4045239.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAVTVKRLHDRGRSGAWAFLMIVAWMLLAGNWAILPGVWQWAVG
                     RFVPTLILVMMLIDLGAFIGTQGENKYGKDTQDVKYKADNKSSN"
     gene            15324..15923
                     /gene="yiiQ"
                     /locus_tag="ACHY1N_002958"
     CDS             15324..15923
                     /gene="yiiQ"
                     /locus_tag="ACHY1N_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HFS4045240.1"
                     /translation="MKPGCTLFFLLCSALTVTTTAHAQTPDTATTAPYLLAGAPTFDL
                     SISQFREDFNSQNPSLPLNEFRAIDSSPDKANLTRAASKINENLYASTALERGTLKIK
                     SIQMTWLPIQGPEQKAAKAKAQEYMAAVIRTLTPLMTKTQSQKKLQSLLTAGKNKRYY
                     TETEGALRYVVADNGEKGLTFAVEPIKLALSESLEGLNK"
     gene            16031..16798
                     /gene="tpiA"
                     /locus_tag="ACHY1N_002959"
     CDS             16031..16798
                     /gene="tpiA"
                     /locus_tag="ACHY1N_002959"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFS4045241.1"
                     /translation="MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPE
                     MYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA"
     gene            complement(16853..17608)
                     /gene="cdh"
                     /locus_tag="ACHY1N_002960"
     CDS             complement(16853..17608)
                     /gene="cdh"
                     /locus_tag="ACHY1N_002960"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008715 - CDP-diacylglycerol diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HFS4045242.1"
                     /translation="MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLP
                     NQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFW
                     LAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
                     ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQS
                     DNSFVLLATQRNLLTLNRASAEEIQDHQCEILR"
     gene            complement(17715..18704)
                     /gene="sbp"
                     /locus_tag="ACHY1N_002961"
     CDS             complement(17715..18704)
                     /gene="sbp"
                     /locus_tag="ACHY1N_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter
                     substrate-binding protein Sbp"
                     /protein_id="HFS4045243.1"
                     /translation="MNKWGVGLTFLLAATSVMAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQQTGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKEWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFVRALYKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     ANELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAK
                     NYYRPRDAEVAKKYENAFPKLKLFTIDEEFGGWTKAQKEHFANGGTFDQISKR"
     gene            complement(19024..19986)
                     /gene="pfkA"
                     /locus_tag="ACHY1N_002962"
     CDS             complement(19024..19986)
                     /gene="pfkA"
                     /locus_tag="ACHY1N_002962"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014072359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFS4045244.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSS
                     HQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY"
     gene            complement(20167..21069)
                     /gene="fieF"
                     /locus_tag="ACHY1N_002963"
     CDS             complement(20167..21069)
                     /gene="fieF"
                     /locus_tag="ACHY1N_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312867.1"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HFS4045245.1"
                     /translation="MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALV
                     DSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGI
                     QHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMM
                     NGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEI
                     IDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFP
                     GSDVIIHQDPCSVVPREGKRSMLS"
     gene            complement(21218..21718)
                     /gene="cpxP"
                     /locus_tag="ACHY1N_002964"
     CDS             complement(21218..21718)
                     /gene="cpxP"
                     /locus_tag="ACHY1N_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HFS4045246.1"
                     /translation="MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKM
                     ANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
                     SNSRSQ"
     gene            21868..22566
                     /gene="cpxR"
                     /locus_tag="ACHY1N_002965"
     CDS             21868..22566
                     /gene="cpxR"
                     /locus_tag="ACHY1N_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HFS4045247.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            22563..23936
                     /gene="cpxA"
                     /locus_tag="ACHY1N_002966"
     CDS             22563..23936
                     /gene="cpxA"
                     /locus_tag="ACHY1N_002966"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HFS4045248.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTV
                     NFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIW
                     LPLYKRS"
     gene            complement(24042..24716)
                     /gene="yiiM"
                     /locus_tag="ACHY1N_002967"
     CDS             complement(24042..24716)
                     /gene="yiiM"
                     /locus_tag="ACHY1N_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-hydroxyaminopurine reductase"
                     /protein_id="HFS4045249.1"
                     /translation="MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTELGLEGDEQ
                     AEKKVHGGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYMGD
                     IFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGKVSADAPL
                     ELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFS
                     RRLWGK"
     gene            complement(24865..25848)
                     /gene="kdgT"
                     /locus_tag="ACHY1N_002968"
     CDS             complement(24865..25848)
                     /gene="kdgT"
                     /locus_tag="ACHY1N_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015649 - 2-keto-3-deoxygluconate:proton
                     symporter activity [Evidence IEA];
                     GO_process: GO:0046411 - 2-keto-3-deoxygluconate
                     transmembrane transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HFS4045250.1"
                     /translation="MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMI
                     TGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVE
                     VGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGT
                     AGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTV
                     IAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEM
                     VPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK"
     gene            complement(26108..26728)
                     /gene="sodA"
                     /locus_tag="ACHY1N_002969"
     CDS             complement(26108..26728)
                     /gene="sodA"
                     /locus_tag="ACHY1N_002969"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_process: GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HFS4045251.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALE
                     SLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAASRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            27013..28047
                     /gene="rhaT"
                     /locus_tag="ACHY1N_002970"
     CDS             27013..28047
                     /gene="rhaT"
                     /locus_tag="ACHY1N_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015153 - rhamnose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008645 - hexose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HFS4045252.1"
                     /translation="MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIV
                     SWIILPWAISALLLPDFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGLSMG
                     IGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKER
                     KMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYV
                     IIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFY
                     AWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVA
                     ANIVGIGMAN"
     gene            complement(28044..28892)
                     /gene="rhaR"
                     /locus_tag="ACHY1N_002971"
     CDS             complement(28044..28892)
                     /gene="rhaR"
                     /locus_tag="ACHY1N_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HFS4045253.1"
                     /translation="MAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIV
                     WRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQG
                     AIPGFSASAGQPHWRLGSVGMAQARQVIGQLEHESSQHVSFANEMAELLFGQLVMLLN
                     RHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTG
                     MTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRH
                     LNSQKD"
     gene            complement(28966..29802)
                     /gene="rhaS"
                     /locus_tag="ACHY1N_002972"
     CDS             complement(28966..29802)
                     /gene="rhaS"
                     /locus_tag="ACHY1N_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HFS4045254.1"
                     /translation="MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLL
                     PQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKS
                     SLQENLENSASRLNLLLAWLEDHFADEVNWDAVAEQFSLSLRTLHRQLKQQTGLTPQR
                     YLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGF
                     LQ"
     gene            30090..31559
                     /gene="rhaB"
                     /locus_tag="ACHY1N_002973"
     CDS             30090..31559
                     /gene="rhaB"
                     /locus_tag="ACHY1N_002973"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFS4045255.1"
                     /translation="MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHS
                     QNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAY
                     RDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLM
                     PDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIG
                     HWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINP
                     NDDRFINPEAMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGE
                     DFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA"
     gene            31556..32815
                     /gene="rhaA"
                     /locus_tag="ACHY1N_002974"
     CDS             31556..32815
                     /gene="rhaA"
                     /locus_tag="ACHY1N_002974"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFS4045256.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VSGFENPEGSLTGGIQATGNYPGKARNASELRTDLEQAMRLIPGPKRLNLHAIYLESD
                     TPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNP
                     AHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINR
                     IAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYC
                     QRHDTPAGSEWLESVRAYEKAILSQRG"
     gene            33057..33881
                     /gene="rhaD"
                     /locus_tag="ACHY1N_002975"
     CDS             33057..33881
                     /gene="rhaD"
                     /locus_tag="ACHY1N_002975"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFS4045257.1"
                     /translation="MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAP
                     YKDNFHAQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGVVKVDSDGAGY
                     HILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAV
                     FTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSG
                     STLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL"
     gene            33891..34205
                     /gene="rhaM"
                     /locus_tag="ACHY1N_002976"
     CDS             33891..34205
                     /gene="rhaM"
                     /locus_tag="ACHY1N_002976"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFS4045258.1"
                     /translation="MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIY
                     LDKARNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFY
                     LP"
     gene            34506..34952
                     /gene="frvA"
                     /locus_tag="ACHY1N_002977"
     CDS             34506..34952
                     /gene="frvA"
                     /locus_tag="ACHY1N_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HFS4045259.1"
                     /translation="MAALTASCIDLNIQGNGAYSVLKQLATIALQNGFITDSHQFLQT
                     LLLREKMHSTGFGSGVAVPHGKSACVKQPFVLFARKAQAIDWKASDGEDVNCWICLGV
                     PQSGEEDQVKIIGTLCRKIIHKEFIHQLQQGDTDQVLALLNQTLSS"
     gene            34963..36414
                     /gene="frvB"
                     /locus_tag="ACHY1N_002978"
     CDS             34963..36414
                     /gene="frvB"
                     /locus_tag="ACHY1N_002978"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIBC"
                     /protein_id="HFS4045260.1"
                     /translation="MESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQG
                     SSGVENRLSSEEIAAADYVILATGRGLSGDDRARFAGKKVYEIAISQALKNIDQIFSE
                     LPTNSHLFAADSGVKLGKQEVQSGSVMSHLMAGVSAALPFVIGGGILVALANMLVQFG
                     LPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLAND
                     KALLSTQSGAGFLGAVVLGLAIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVL
                     TYYVIGPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSL
                     LEKHIYDWYAIVGVVALMPPVAAGLATFIAPKLFTRQEKEAASSAIVVGATVATEPAI
                     PYALAAPLPMITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVGSFYLVLA
                     IGLALNISFIIVLKGLWLRRKAKAAQQELVHEH"
     gene            36404..37474
                     /gene="frvX"
                     /locus_tag="ACHY1N_002979"
     CDS             36404..37474
                     /gene="frvX"
                     /locus_tag="ACHY1N_002979"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709702.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFS4045261.1"
                     /translation="MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGS
                     FVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRFTTIGGWWNQSMLNHRVTIRTHK
                     GVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSRDEVEKRGVAMGDFISPEAN
                     FACWGEDKVVGKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEH
                     IKPDVVIVLDTAVAGDVPGIDNIKYPLKLGQGPGLMLFDKRYFPNQKLVAALKSCAAH
                     NDLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSGMISKADYDALLTLI
                     RDFLTTLTAEKVNAFSQFRQVD"
     gene            37474..39222
                     /gene="frvR"
                     /locus_tag="ACHY1N_002980"
     CDS             37474..39222
                     /gene="frvR"
                     /locus_tag="ACHY1N_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative frv operon regulatory protein"
                     /protein_id="HFS4045262.1"
                     /translation="MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFT
                     LNGKARISASGSAGYQLEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALN
                     LPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLA
                     GVTRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIV
                     EHSGLFLGDNAVRTLTGLIEKQHQQAQIISADNVQRLLQRVPGIASLNIIDTQLVENI
                     TGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLREQLDIPLFDSDLIG
                     LYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLHCRVIIARSLSELVAIREE
                     IEPLLIINNSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGS
                     FHYSNVRGESWQHITRQICAQLVAQHHITADEAQRIIAREGEGENLIVNRLAIPHCWS
                     EQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASVLCQHPAEVI
                     AGLTGYEAFMELLHKG"
     gene            complement(39272..>40307)
                     /gene="yiiG"
                     /locus_tag="ACHY1N_002981"
     CDS             complement(39272..>40307)
                     /gene="yiiG"
                     /locus_tag="ACHY1N_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YiiG family protein"
                     /protein_id="HFS4045263.1"
                     /translation="RNLLSSAIIVAIMALGLTGCDDKKAETETPPPANSQPAAPAPEA
                     PVAKAEAKPETPAQPVVDEQAVFDEKMDVYIKCYNKLQIPVQSSLARYADWLKDFKQG
                     PTGEERTVYGIYGISESNLAECEKGVKSAVALTPALQPIDGVAVSYIDAAVALGNTIN
                     EMDKYYTQENYKDDAFAKGKTLHQTFLKNLEAFEPVAESYHAAIQEINDKRQLAELKN
                     IEEREGKTFHYYSLAVMISAKQINNLISQEKFDVDAAMKKVSELETLVAQAKEADKGG
                     MNFSFINSAGQYQLEAKKYVRRIRDKVPYSDWDKEQLQDANSSWMVEDSFPRALREYN
                     EMVDDYNSLR"
BASE COUNT         9785 a        10463 c        10423 g         9636 t
ORIGIN      
        1 ggattgaccg gatggccgga cgtcaccccg ccgtggcaca ccgaacaggc cacgccggtg
       61 ggggcaccga tgcgcacccc ggctgaaccc tggacaatgc taccgccata ctgcgtcatg
      121 tcgccctgac gcgccgccgg ttttccgctc atcgtaaaat ccttttgaaa taaataagaa
      181 ccagaagcct agcgccagtc aacaacagga aatgataatg agttaacacc ccggaatttt
      241 tcagaattta taaaaggcaa attacaggca caaaaaaagc gccgtgcggc gcttttttcg
      301 gaaatccggt cttatttgct gcccgggatg ttgaaacgct tgttgaagcg gtcaacacgg
      361 ccaccggtag caacatcacg ctgtttgcca gtgaagaacg ggtggcactt gctgcacacg
      421 tcgaggttca ggtcatgacc aacggtggag cggattttca ttacgttacc gcaagagcag
      481 ctagcagtaa tttcttcgta tttcgggtga atatcttttt tcatgggaaa acctcggttt
      541 aaggccgcgt cgctcttcca gccctaacgc cagacaccac gcgatgttaa aagtatagct
      601 tcaatacgat catttcgtac gaaggcgcga aatcatacag aaattaacca gcgtatgcaa
      661 actgatccgc actcttctac ggcaatgtgt atactaaccc accgaatttc aagtcaggat
      721 gatgctatgc ccgttgccca cgttgccttg cccgttccgc ttcctcgtac ctttgactat
      781 ctgctgccag aaggcatgac ggttaaagcc gggtgtcgcg tgcgcgtgcc gtttggcaaa
      841 cagcaggagc gcatcggggt tgtggtgtca gttagcgatg tcagtgagct gccgcttaac
      901 gagctgaaag cggtagtgga agtgctggac gttgagccgg tatttactca ctccgtctgg
      961 cggttactgc tctgggcggc agattactat catcatccga ttggcgatgt gctgtttcat
     1021 gccttgccga ttttactgcg ccaggggcgg cctgcggcga acgcgccgat gtggtactgg
     1081 tttgccactg aacaaggcca ggcggtggat ctgaacagcc tgaaacgctc ccccaagcaa
     1141 caacaggcgc tggcggcgtt acggcaaggc aaaatctggc gcgaccaggt cgccacgctc
     1201 gaatttaatg atgccgcgtt gcaggcgcta cgcaaaaaag gtctgtgtga tttagcaagt
     1261 gaaacaccag agtttagcga ctggcaaacg aactatgccg tttctggtga gcggttgcga
     1321 ttgaataccg aacaggccac cgccgttggc gcaattcata gcgcggcaga tactttttct
     1381 gcctggctgc tggcgggcgt taccggttcc ggtaaaacgg aggtttatct cagtgtactg
     1441 gaaaacgtgc tcgctcaggg caaacaggcg ctggtgatgg tgccggaaat cggcctgaca
     1501 ccgcaaacta tcgcccgttt tcgtgaacgt tttaatgccc ccgtggaagt tctgcattcc
     1561 ggcctgaacg acagcgagcg gctttcggcg tggttgaaag cgaaaaatgg cgaggcggcg
     1621 attgtgatcg gcacccgctc cgcgctgttt acgccgttta aaaatctcgg cgtgattgtc
     1681 attgatgaag agcacgacag ctcctacaag cagcaggaag gctggcgcta tcatgcccgc
     1741 gacctggcgg tgtatcgtgc gcatagcgag caaatcccga ttattcttgg ctccgcaacg
     1801 cccgcgctgg aaacgttgtg caacgtccag cagaaaaaat accgcctgct gcgcctgacg
     1861 cgccgggcgg ggaatgcgcg tccggcaatt caacacgtgc tggatttaaa aggtcagaag
     1921 gtgcaggcag gtctggctcc ggcgttaatc acccgtatgc gccagcattt acaggccaac
     1981 aatcaggtta tcctctttct taatcgtcgg ggttttgcgc ctgcgctact gtgccacgac
     2041 tgcggctgga ttgccgaatg cccacgttgc gatcactact acacgctgca tcaggcgcaa
     2101 cagcatttgc gctgtcacca ctgtgacagt cagcgtccgg tgccgcgcca gtgcccttcc
     2161 tgcggttcca cgcacctggt acccgtgggg ctgggcaccg aacagcttga acagacgctt
     2221 gcgccgctgt tccctgatgt gcccatttct cgtatcgacc gcgataccac cagccgcaaa
     2281 ggggcgctgg aacagcaact ggcggaagta catcgcggcg gtgcgaggat tttgatcggc
     2341 acacaaatgc tggcgaaagg tcaccacttt ccggatgtga cgctggtggc gttactggat
     2401 gtggacggcg cgctgttttc tgccgatttt cgctcggcag agcgtttcgc tcagctttac
     2461 acccaggtcg ctggtcgtgc cgggcgtgcg ggtaaacaag gcgaagtggt gctgcaaacg
     2521 caccatccag aacatcctct gttgcaaacg ttgctctata aaggctacga cgcctttgcc
     2581 gaacaggcgc tggctgagcg acggatgatg caactgccgc catggaccag ccatgtgatt
     2641 gtgcgtgcgg aagatcataa caatcagcat gcgccgctgt tcctgcaaca actgcgtaat
     2701 ctgatcctct ccagcccgct ggcagacgac aaactgtggg ttctcggtcc ggttccggca
     2761 ctggcaccta aacgtggcgg tcgctggcgc tggcagatat tgttgcagca cccttcccgc
     2821 gtgcgcttgc aacacatcat tagtggtacg ctggcgctca tcaatacaat accggattcc
     2881 cgcaaggtga aatgggtact ggatgttgat ccgattgagg gttaaaccgc ttacgatgcg
     2941 aggcggatcg aaaaattcaa tattcatcac acttttcatg aaaattctgt aaccgttttc
     3001 acgcgctatc tgctaaaaat gttgccgatg tgaagtaaac atggatgtag tacgcctgac
     3061 gtgccaggcg aggagtgagt gtgaaagcga agaagcagga aactgccgcg accatgaaag
     3121 acgttgccct caaggcaaaa gtctctacag cgactgtctc ccgagcatta atgaatcccg
     3181 ataaagtctc ccaggccacc cgtaatcggg ttgaaaaagc ggcccgggaa gtgggttatt
     3241 taccgcagcc tatggggcgc aacgtcaagc gtaatgaatc ccgcaccatt ctggtgattg
     3301 tcccggatat ctgcgatccc ttctttagcg aaattattcg cggtatcgaa gttacggcgg
     3361 caaatcacgg atatctggtg ctgattggcg actgtgcgca tcaaaatcag caggaaaaaa
     3421 cctttatcga tttgatcatc accaagcaaa ttgatggcat gttgctgctg ggttcaaggc
     3481 tgccgtttga tgccagcatt gaggaacagc gtaatctgcc gccgatggtg atggcgaacg
     3541 aattcgcacc ggaactggag ctacctacag ttcatatcga caatctgacc gccgcatttg
     3601 atgcagtaaa ttatctatat gagcaagggc ataaacggat tggctgtata gccggtcccg
     3661 aagagatgcc gctgtgtcac taccgcctgc aaggttacgt tcaggcgctg cgtcgctgcg
     3721 gcattatggt tgatccgcaa tacatcgccc gtggcgactt caccttcgaa gccggaagca
     3781 aagcgatgca gcagctgctt gatcttccac aaccgcctac tgctgtcttc tgccatagcg
     3841 atgtgatggc gctcggcgca ctttctcagg caaaacgcca ggggctgaaa gtcccggaag
     3901 acctttccat aatcggtttt gataacatcg acctgacgca attttgtgat ccgccgctga
     3961 caaccatcgc gcagccgcgt tacgaaatcg gtcgggaagc tatgctgtta ttgcttgatc
     4021 aaatgcaggg gcaacacgtt ggcagtggct ctcgtttaat ggactgcgaa cttatcatcc
     4081 ggggatcaac acgcgcgtta ccttaaagta aacctttaag actgccgtga ctggtcaaag
     4141 gcccgccgct taagtaacat ggcgggctga cgaacgaata aatacagcga aacgatagtg
     4201 gcacaacgag attatgtacg ccgcagccaa ccggcacctt cgcggcgaaa aaagagcacc
     4261 tcacggaaaa agcaacgaaa tctgcctgcg gtttctcccg ctatggtcgc tattgctgcc
     4321 gccgttcttg tgacctttat cggtggtctg tacttcatta cgcatcacaa gaaagaagag
     4381 tccgagacgc tgcaaagcca gaaagtgacc ggtaacggac taccaccaaa accagaagaa
     4441 cgctggcgct acattaaaga gctggaaagt cgccagccgg gtgtgcgtgc gcccacagaa
     4501 ccttctgccg gtggtgaagt gaaaacgccg gagcaactga caccagaaca acgtcagctt
     4561 cttgaacaaa tgcaggctga tatgcgccag cagccaacgc agctggttga agttccgtgg
     4621 aatgaacaga cgccggaaca gcgtcagcaa acgctacaac gccagcgtca ggcgcagcaa
     4681 ttagcggagc agcaacgcct ggctcagcag tcgcgtacga ctgaacaaag ctggcagcag
     4741 cagacgcgta cgtcgcaagc cgcgccggta caggcgcaac cgcgccagtc taaaccggct
     4801 tctactcagc agccgtacca ggatctgctg caaacccctg cgcacacgac cgcgcagtcg
     4861 aagccgcagc aagctgcgcc ggttgctcgt gccgctgacg cgccaaaacc gacggcggag
     4921 aaaaaagacg aacgccgctg gatggtgcag tgcggttcgt tcagaggcgc ggaacaggca
     4981 gatacggtac gtgctcagct ggcgttcgaa ggatttgact cgaaaatcac caccaacaat
     5041 ggctggaatc gtgtggtcat tggcccggtg aaaggcaaag agaacgcaga cagcaccctc
     5101 aatcggttga agatggcggg tcatacaaac tgcattcggc tcgccgccgg gggttgaaac
     5161 cctcaaaatc ccccccatct ataattgcat tatgccccgt acttttgtac ggggtttgta
     5221 ctctgtattc gtaaccaagg ggtcagctcg tgacaactat agtaagcgta cgccgtaacg
     5281 gccatgtggt catcgctggt gatggtcagg ccacgttggg caataccgta atgaaaggca
     5341 acgtgaaaaa ggtccgccgt ctgtacaacg acaaagtcat cgcgggcttt gcgggcggta
     5401 ctgcggatgc ttttacgctg ttcgaactgt ttgaacgtaa actggaaatg catcagggcc
     5461 atctggtcaa agccgccgtt gagctggcga aagactggcg taccgatcgc atgctgcgca
     5521 aacttgaagc actgctggca gtcgcggatg aaactgcatc gcttatcatc accggtaacg
     5581 gtgacgtggt gcagccagaa aacgatctta ttgctatcgg ctccggcggc ccttacgccc
     5641 aggctgcggc gcgtgcactg ttagaaaata ctgaactgag tgctcgtgaa attgctgaaa
     5701 aggcgttgga tattgcaggc gacatttgca tctataccaa ccatttccac accatcgaag
     5761 aattaagcta caaagcgtaa ggatctccca tgtctgaaat gaccccacgc gaaatcgtca
     5821 gcgaactgga taagcacatc atcggccagg acaacgccaa gcgttctgtg gcgattgctc
     5881 tgcgtaaccg ctggcgtcgc atgcagctca acgaagagct gcgccatgaa gtgaccccga
     5941 aaaatatcct gatgatcggc ccgaccggtg tcggtaaaac tgaaatcgcc cgtcgtctgg
     6001 ctaagctggc gaatgcgccg ttcatcaaag ttgaagcgac caaattcacc gaagtgggct
     6061 acgtcggtaa ggaagtggat tctattattc gcgatctgac cgatgccgcc gtgaaaatgg
     6121 tacgcgtcca ggctatcgag aaaaaccgtt atcgcgctga agaactggca gaagaacgta
     6181 ttctcgacgt gctgatccca cctgctaaaa acaactgggg acagaccgaa cagcagcagg
     6241 aaccgtccgc tgctcgtcag gcattccgca aaaaactgcg tgaaggccag cttgatgaca
     6301 aagaaatcga gatcgatctt gccgcagcac cgatgggcgt tgaaattatg gctcctccag
     6361 gcatggaaga gatgaccagc cagctgcagt ccatgttcca gaacctgggc ggccagaagc
     6421 aaaaagcgcg taagctgaaa atcaaagacg ccatgaagct gctgattgaa gaagaagcgg
     6481 cgaaactggt gaacccggaa gagctgaagc aagacgctat cgacgctgtt gagcagcacg
     6541 ggatcgtgtt tatcgacgaa atcgacaaaa tctgtaagcg cggcgagtct tccggtccgg
     6601 atgtttctcg tgaaggcgtt cagcgtgacc tgctgccgct ggtagaaggt tgcaccgttt
     6661 ccaccaaaca cgggatggtc aaaactgacc acattctgtt tatcgcttct ggcgcgttcc
     6721 agattgcgaa accgtctgac ctgatcccgg aactgcaagg tcgtctgcca atccgcgttg
     6781 aactgcaggc gctgaccacc agcgacttcg agcgtattct gaccgagccg aatgcctcta
     6841 tcaccgtgca gtacaaagca ctgatggcga ctgaaggcgt aaatatcgag tttaccgact
     6901 ccggtattaa gcgcatcgcg gaagcggcat ggcaggtgaa cgaatctacc gaaaacatcg
     6961 gtgctcgtcg tttacacact gttctggagc gtttaatgga agagatttcc tacgacgcca
     7021 gcgatttaag cggtcaaact atcatcattg acgcagatta tgtgagcaaa catctggatg
     7081 cgttggtggc agatgaagat ctgagccgtt ttatcctata atcgcgttca atcattttca
     7141 tcattgtttg atggggctga aaggccccat ttttattggc gcgtattatg actgaacaac
     7201 aaattagccg aactcaggcg tggctggaaa gtttacgacc taaaaccctc cccctcgcct
     7261 ttgctgcaat tatcgtcggg acagcgctgg catggtggca aggtcacttc gatccgctgg
     7321 tcgccctgct ggcactgatt accgccgggc tattacagat cctttctaac ctcgccaatg
     7381 attacggcga tgcggtaaaa ggcagcgata aacctgaccg cattgggccg ctacgcggca
     7441 tgcaaaaagg ggtcattacc cagcaagaga tgaaacgggc gctcattatt accgtcgtgc
     7501 tcatctgtct ctccgggctg gcactggttg cagtggcatg ccatacgctg gccgattttg
     7561 tcggtttcct gattcttggc gggttgtcga tcattgccgc tatcacctac accgtgggca
     7621 atcgtcctta tggttatatc ggtctgggtg atatttccgt actggttttc tttggctggt
     7681 tgagtgtcat ggggagctgg tatttacagg ctcatacatt gattccggca ctgatccttc
     7741 cggcgaccgc atgcggcctg ctggcaacgg cagtactgaa tattaataac ctgcgtgata
     7801 tcaatagcga ccgcgaaaat ggcaaaaaca cgctggtggt gcgcttaggt gaagtgaacg
     7861 cgcgtcgtta tcatgcctgc ctgctgatgg gctcgctggt gtgtctggcg ctgtttaatc
     7921 tcttttcgct gcatagcctg tggggctggc tgttcctgct ggcggcacca ttactggtga
     7981 agcaagcccg ttatgtgatg cgggaaatgg acccggtggc gatgcgacca atgctggaac
     8041 gtactgtcaa gggagcgtta ctgactaacc tgctgtttgt tttagggata ttcctaagcc
     8101 agtgggcagc ataactgaca aatatcaatt aacaattgat gattttgcca acagcccaca
     8161 tagcgcgata tactgaaaat tctcgcagca actgaatgtt aagcctatga aatacgatac
     8221 ttccgagctt tgtgacatct atcaagaaga tgttaacgtc gtggaaccgc tgttctccaa
     8281 ctttggcgga cgggcgtcgt ttggcggaca aataatcacg gtaaaatgtt tcgaggacaa
     8341 cgggttgctg tacgatctgc tcgaacagaa tggccgtggt cgtgttcttg tcgtcgatgg
     8401 cggtggttct gttcgtcgcg cactggtcga tgctgaactg gcgcgtctgg cagtacaaaa
     8461 tgaatgggaa ggtctggtca tttacggcgc ggtgcgtcag gtagatgacc tggaagagtt
     8521 ggatatcggc atccaggcga tggcggcaat tccggttggt gccgctggcg aaggcattgg
     8581 cgaaagcgat gtccgcgtca attttggcgg tgtcaccttc ttctccggcg accatcttta
     8641 tgccgacaat accgggatta ttctttctga agatccgctg gatattgaat gatagaaaag
     8701 gcaccgcaag gtgccttttt tctgcgttac ctgttggcct acacagtaaa gaaattacgc
     8761 ggaagatgaa gcgtaatcag acctcttcca tgcgacccag cagggcctgc agacgttcct
     8821 gccagccgtt ctgctgttct ttcagatggt tgttctcacg ctccagctct tcgcgctgat
     8881 gctgggcatt ttgaacttcc tgcgacagtg agttgttttt ttctttcagc tcttcgattt
     8941 ccatctgcaa cagagtgatg gtatcaatcg cctgctgtac ttttgcttcc agtttctcaa
     9001 acacttctaa tgacattgtc atacctctcc tgaattgcaa ggcgttgatg gataaaaatc
     9061 ctcgtcccga ttaccggtga cgccttaata aatacgagcg cactttagtt agctccgatt
     9121 gtatgaagcc gcgccatcgc tgtccagcgg cacgccttgc agattacggt ttgccacact
     9181 tttcatcctt ctcctggtga cataatccac atcaatcgaa aatgttaata aatttgttgc
     9241 gcgaatgatc taacaaacat gcatcatgta caatcagatg gaataaatgg cgcgataacg
     9301 ctcattttat gacgaagcac acacatttta agttcgatat ttctcgtttt tgctcgttaa
     9361 cgataagttt acagcatgcc tacaagcatc gtggaggtcc gtgactttca cgcatacaac
     9421 aaacattaac tcttcaggat ccgattatga gtcaaacatc aaccttgaaa ggccagtgca
     9481 ttgctgaatt cctcggtacc gggttgttga ttttcttcgg tgtgggttgc gttgcagcac
     9541 taaaagtcgc tggtgcgtct tttggtcagt gggaaatcag tgtcatttgg ggactggggg
     9601 tggcaatggc catctacctg accgcagggg tttccggcgc gcatcttaat cccgctgtta
     9661 ccattgcatt gtggctgttt gcctgtttcg acaagcgcaa agttattcct tttatcgttt
     9721 cacaagttgc cggcgctttc tgtgctgcgg ctttagttta cgggctttac tacaatttat
     9781 ttttcgactt cgagcagact catcacattg ttcgcggcag cgttgaaagt gttgatctgg
     9841 ctggcacttt ctctacttac cctaatcctc atatcaattt tgtgcaggct ttcgcagttg
     9901 agatggtgat taccgctatt ctgatggggc tgatcctggc gttaacggac gatggcaacg
     9961 gtgtaccacg cggccctttg gctcccttgc tgattggtct actgattgcg gtcattggcg
    10021 catctatggg cccattgaca ggttttgcca tgaacccagc gcgtgacttc ggtccgaaag
    10081 tctttgcctg gctggcgggc tggggcaatg tcgcctttac cggcggcaga gacattcctt
    10141 acttcctggt gccgcttttc ggccctatcg ttggcgcgat tgtaggtgca tttgcctacc
    10201 gcaaactgat tggtcgccat ttgccttgcg atatctgtgt tgtggaagaa aaggaaacca
    10261 caactccttc agaacaaaaa gcttcgctgt aatatgacta cgggacaatt aaacatgact
    10321 gaaaaaaaat atatcgttgc gctcgaccag ggcaccacca gctcccgcgc ggtcgtaatg
    10381 gatcacgatg ccaatatcat tagcgtgtcg cagcgcgaat ttgagcaaat ctacccaaaa
    10441 ccaggttggg tagaacacga cccaatggaa atctgggcca cccaaagctc cacgctggta
    10501 gaagtgctgg cgaaagccga tatcagttcc gatcaaattg cagctatcgg tattacgaac
    10561 cagcgtgaaa ccactattgt ctgggaaaaa gaaaccggca agcctatcta taacgccatt
    10621 gtctggcagt gccgtcgtac cgcagaaatc tgcgagcatt taaaacgtga cggtttagaa
    10681 gattatatcc gcagcaatac cggtctggtg attgacccgt acttttctgg caccaaagtg
    10741 aagtggatcc tcgaccatgt ggaaggctct cgcgagcgtg cacgtcgtgg tgaattgctg
    10801 tttggtacgg ttgatacgtg gcttatctgg aaaatgactc agggccgtgt ccatgtgacc
    10861 gattacacca acgcctctcg taccatgttg ttcaacatcc ataccctgga ctgggacgac
    10921 aaaatgctgg aagtgctgga tattccgcgc gagatgctgc cagaagtgcg tcgttcttcc
    10981 gaagtatacg gtcagactaa cattggcggc aaaggcggca cgcgtattcc aatctccggg
    11041 atcgccggtg accagcaggc cgcgctgttt ggtcagttgt gcgtgaaaga agggatggcg
    11101 aagaacacct atggcactgg ctgctttatg ctgatgaaca ctggcgagaa agcggtgaaa
    11161 tcagaaaacg gcctgctgac caccatcgcc tgcggcccga ctggcgaagt gaactatgcg
    11221 ttggaaggtg cggtgtttat ggcaggcgca tccattcagt ggctgcgcga tgagatgaag
    11281 ttgattaacg acgcctacga ttccgaatat ttcgccacca aagtgcaaaa caccaatggt
    11341 gtgtatgtgg ttccggcatt taccgggctg ggtgcgccgt actgggaccc gtatgcgcgc
    11401 ggggcgattt tcggtctgac tcgtggggtg aacgctaacc acattatacg cgcgacgctg
    11461 gagtctattg cttatcagac gcgtgacgtg ctggaagcga tgcaggccga ctctggtatc
    11521 cgtctgcacg ccctgcgcgt ggatggtggc gcagtagcaa acaatttcct gatgcagttc
    11581 cagtccgata ttctcggcac ccgcgttgag cgcccggaag ttcgcgaagt gactgcattg
    11641 ggtgcggcct atcttgctgg tctggcggtc ggtttctggc agaacctcga cgagctgcaa
    11701 gagaaagcgg tgattgaacg cgagttccgt ccaggcatcg aaaccactga gcgtaattac
    11761 cgttacgcag gctggaaaaa agcggtcaaa cgcgcgatgg cgtgggaaga acacgacgag
    11821 taatgtaaat gccggatgaa gcgtttatgc cgcatccggt agtcctgaaa ccgtgcgggg
    11881 gcaaccccgc acacatcaat aatcccaccc ttcccctgtg ctacacttcg cgccattcct
    11941 tactgcttag agtttgctat gagacgagaa cttgccatcg aattttcccg cgtcaccgaa
    12001 tctgcggcgc tggctggcta caaatggtta ggacgcggcg ataaaaacac cgcggacggc
    12061 gcggcggtaa acgccatgcg tattatgctc aaccaggtca acattgacgg caccatcgtc
    12121 attggtgaag gtgaaatcga cgaagcaccg atgctctaca ttggtgaaaa agtcggtact
    12181 ggtcgcggcg acgcggtaga tattgctgtt gatccgattg aaggcacgcg catgacggcg
    12241 atgggccagg ctaacgcgct ggcggtgctg gcagtaggcg ataaaggctg cttcctcaat
    12301 gcgccggata tgtatatgga gaagctgatt gtcgggccgg gagccaaagg caccattgat
    12361 ctgaacctgc cgctggcgga taacctgcgc aatgtagcgg cggcgctcgg caaaccgttg
    12421 agcgaactga cggtaacgat tctagctaaa ccacgccacg atgccgttat cgctgaaatg
    12481 cagcaactcg gcgtacgcgt atttgctatt ccggatggcg acgttgcggc ctcaattctc
    12541 acctgtatgc cagacagcga agttgacgtg ctgtacggta ttggtggcgc gccggaaggc
    12601 gtagtttctg cggcggtgat ccgcgcatta gatggcgaca tgaacggtcg tctgctggcg
    12661 cgtcatgacg tcaaaggcga caacgaagag aatcgtcgca ttggcgagca ggagctggca
    12721 cgctgcaaag cgatgggcat cgaagccggt aaagtattgc gcctgggcga tatggcgcgc
    12781 agcgataacg tcatcttctc tgccaccggt attaccaaag gcgatctgct ggaaggcatt
    12841 agccgcaaag gcaatatcgc gactaccgaa acgctgctga tccgcggcaa gtcacgcacc
    12901 attcgccgca ttcagtccat ccactatctg gatcgcaaag acccggaaat gcaggtgcac
    12961 atcctctgat tgatttgatc gattgagcct tccagtcctt cgggactgga atttttttgt
    13021 tcggagaacg aagataaggc aagttaatca aaacaggaga aaaacatggc tgattgggta
    13081 acaggcaaag tcactaaagt gcagaactgg accgacgccc tgtttagtct caccgttcac
    13141 gcccccgtgc ttccgtttac cgccgggcaa ttcaccaagc ttggccttga aatcgacggc
    13201 gaacgcgtcc agcgcgccta ctcctatgtt aactcgcccg ataatcccga tctggagttt
    13261 tacctggtca ccgtccccga tggcaaatta agcccacgat tggcggcact gaaaccaggc
    13321 gatgaagtgc aggtggttag cgaagcagct ggcttctttg ttctggatga agtaccggac
    13381 tgcgaaacgc tatggatgct ggcaaccggt acagcgattg gcccttattt atcgattctg
    13441 caactaggca aagatttaga tcgcttcaaa aatctggtcc tggttcacgc cgcacgttat
    13501 gccgccgact taagctattt gccactgatg caagaactgg aaaaacgcta cgaagggaaa
    13561 ctgcgcattc agacggtggt cagtcgggaa acggcagcgg ggtcgctcac cgggcggata
    13621 ccggcgttaa ttgaaagtgg ggaactggaa agcgcgattg gcctgccgat gaataaagaa
    13681 accagccatg tgatgctgtg cggcaatcca cagatggtgc gcgatacaca acagttgctg
    13741 aaagagaccc ggcagatgac gaaacattta cgtcgccgac cgggccatat gacagcggag
    13801 cattactggt aagcggttac ttatcgataa acggcacgat gagcaaatcc gcactcatct
    13861 tattgatcat cccgcgatat gccggcatca aacggttgat aaatgagtga tgatgaccac
    13921 agacaaggag gtcgcactgc tctttttgca taatttccag cagtgtttcc ggcatttctc
    13981 cgcgttcaat acgcagtttt gtcttcggcc attgaatatt tttcgtcagt ttatacagct
    14041 tgttatccga cttattcttc aacaattgaa gaatatcttc tgttgcaggg aagtagatac
    14101 ccggatacaa ctcgcttaag ccatcatcaa tatgaattaa cgtcaggtga gcgtcattat
    14161 gtctggcgag ctccagagct ttattcacca gtaaggcatc ttcttcattc ccggaaattg
    14221 ccacgccaat gtgtttataa gccatgttta actccttcta aagcaactcc atcaagctaa
    14281 cgaacgcagt gataactcaa aaataatcat ctcggcctgg catgagaaag tgaaggccgc
    14341 atcaagctca acttgcccct ccagatcctt aatcttgtag gccacgctgg ccccttcatc
    14401 tgcagaggat gcagcggcgg caagctcttt cagtttggtc ataaaagact ctgcttcttc
    14461 gcgggtggca aaaaagcgcg aaaacttact ggtacagttg tcgttatcaa tcaccgtacc
    14521 gatatcaatc gcacatcctt tagtactgca tttatctacg acatctttca tagggcacct
    14581 ctgtatattc gcctctctgt cgattacgac ttaagaataa tgcgccgtta agggaagaac
    14641 aaacaagtaa tgatcttatg gattaccatt ttttttgata ttgcttaagg tgaagagttc
    14701 agaaggattt tccgggcatt gtcatttgca tcgtggaaat aacaatcccg gaaaaaaata
    14761 gcagtaagag atatattaaa ggttaattac ttgatttatt gtcggcttta tacttcacat
    14821 cctgggtatc tttaccatat ttattttcgc cttgtgtgcc aatgaacgct ccaagatcga
    14881 taagcatcat caccagaatc aacgtcggga caaaacgccc caccgcccat tgccagacac
    14941 ccggtaaaat cgcccagtta cccgccagca gcatccacgc cacaatcatc agaaatgccc
    15001 atgcgccgga acgcccgcga tcatgcaagc gcttaacggt tactgccgct gttggccaaa
    15061 gcaagcacac aaggcaaaac gccgcggtct gaatatcgag taaattttta cccgccagtg
    15121 agaaaagcac cagcatgcct gcgaaccaca ggcctatcca aatccagaaa tcacggcgtc
    15181 caatacgccc tttaaatgag aataaccatt gctgtatggt catgtaagtt ccttgatggt
    15241 tgtcttttcc aggattctac ccttttgaca agggcgacag atatcgtttt aatcggagcc
    15301 agtcataaca aaaggtactg tcaatgaagc cagggtgtac gctgtttttt ctcttatgtt
    15361 ctgcattaac cgttacaaca acggcgcatg cacaaacacc agatacggca acgaccgcgc
    15421 cttatctgct ggctggagcc cctactttcg atctctccat cagccagttt cgagaagact
    15481 ttaacagcca gaatcccagc ctgccactga acgaatttcg tgccatcgac agcagtcccg
    15541 acaaagccaa tctcactcgt gctgcaagta aaattaacga gaacttgtat gcttctacag
    15601 cgctggagcg cggtacctta aaaatcaaaa gcattcaaat gacctggcta cccatccagg
    15661 ggccagagca aaaagcagcg aaagcgaaag ctcaggaata catggcagca gtgatccgca
    15721 cactcacccc attaatgacc aaaacacaaa gccagaaaaa actgcagtcg ctgctaacgg
    15781 cggggaaaaa caaacgttat tacaccgaga cagaaggtgc actgcgttat gttgtcgcgg
    15841 acaacggcga aaaggggctg accttcgctg ttgaaccgat taagctggcg ctatctgaat
    15901 cgcttgaagg tttgaataaa tgacaaaaag caaagccttt gtgccgatga atctctatac
    15961 tgtttcacag acctgctgcc ctgcggggcg gccatcttcc tttattcgct tataagcgtg
    16021 gagaattaaa atgcgacatc ctttagtgat gggtaactgg aaactgaacg gcagccgcca
    16081 catggttcac gagctggttt ctaacctgcg taaagagctg gcaggtgttg ctggctgtgc
    16141 ggttgcaatc gcaccaccgg aaatgtacat cgatatggcg aagcgcgaag ctgaaggcag
    16201 ccacatcatg ctgggtgcgc aaaacgtgga cctgaacctg tccggcgcat tcaccggtga
    16261 aacttctgcc gctatgctga aagacatcgg cgctcagtac atcatcatcg gccactctga
    16321 acgtcgtact taccacaaag agtctgacga actgatcgcg aaaaaattcg cggtgctgaa
    16381 agagcagggc ctgactccgg ttctgtgcat cggtgaaacc gaagctgaaa acgaagcggg
    16441 caaaactgaa gaagtttgcg cacgtcagat cgacgcggta ctgaaaactc agggtgctgc
    16501 ggcattcgaa ggtgcggtta tcgcttacga acctgtatgg gcaatcggta ctggcaaatc
    16561 tgcaactccg gctcaggcac aggctgttca caaattcatc cgtgaccaca tcgctaaagt
    16621 tgacgctaac atcgctgaac aagtgatcat tcagtacggc ggctctgtaa acgcgtctaa
    16681 cgctgcagaa ctgtttgctc agccagatat cgacggcgcg ctggttggcg gtgcttctct
    16741 gaaagctgac gctttcgcag taatcgttaa agctgcagaa gcggctaaac aggcttaagt
    16801 ctgacaggtg ccggatttca tatccggcac ttactttcct taactcttcg ccttaacgca
    16861 aaatctcaca ctgatgatcc tgaatttcct cggctgaagc acggttaagc gtcagtagat
    16921 ttcgttgtgt cgccagcaat acaaatgagt tatcactctg ccgtaccatc gccagcccgt
    16981 agcttcccat atgttcccgc gcctcaggta cttcttctgc cagcatcata aatgggctgc
    17041 gttgtaccag ttcgctttcc gttacccgac gcgccaggta ttcatgcccg cgcaaaccac
    17101 ctggcagtgg caaccagcgg ctgctgatgt tcgccagatt gttatccagt tgttcgcgca
    17161 catcaggacg aatacaagag atatgaatat gaaaatggtt ttgcgtacgc ccggtgcggg
    17221 agttgatcgc caaagaaacc gcgcgatcgg gaaccggctg gccgtatttt ttgctcataa
    17281 aatcacgcgc ctgccaggcc aaccaaaaga agttcggcgt tgaaggatcg gtcaacaaag
    17341 gactttcagt accgttaata cgatacgttg gcatcaacag atattgcagt ggaccattaa
    17401 gatcttttaa aaccacgtat ccggcattgg gtttgacttc cgcacatggc gaaggatttt
    17461 gattttgctg ctgattgggc aaacattcct caaggacaat cttacgtaat gtatccgact
    17521 cttcaccggt taatttccag taaccaatac cggcagccac aacggcgata actatcatca
    17581 ccaaaaaaag aagacccgct tttttcatct ttttttccct gtacctcaaa gagatgcaag
    17641 ggtaacgcaa aatcgtgaca aataaaaaac ccggtcacga gaaaccaccg ggtttgataa
    17701 ttatcctggg gaaatcagcg tttgctgatc tgatcgaacg taccgccgtt agcaaaatgc
    17761 tctttttgcg ctttcgtcca gccgccgaac tcttcatcaa tggtgaataa cttcagcttt
    17821 ggaaacgcat tttcgtactt tttcgccacc tcagcgtcgc gcggacggta gtagtttttc
    17881 gcggcaattt cctgaccttc tggcgagtag agatatttca ggtaggcttc cgccacctct
    17941 ttggtgcctt ttttctcgac cactttatcg accaccgaca cggttggctc tgcgaggata
    18001 gactcactcg gcgtgacgat ttcgaattta tctttcccca gttcattcgc tgccagcaga
    18061 gcttcgtttt cccaggcgat cagtacatcg ccaatcccgc gctcgacaaa ggtgttagtg
    18121 gagccgcgcg cgccagaatc cagaacttcg acgtttttat acagtgcccg aacaaaatcc
    18181 tgtgcttttg cctgatcgtt gttgttgtga tgcagcgcgt agccccaggc agccaggtag
    18241 ttccagcgtg cgccaccaga gcttttcgga ttaggcgtga tcaccgaaac acccggttta
    18301 atcagatcgt tccagtcatg gatctgcttc ggattgccct tacgcaccag gaaaacaatg
    18361 gtggaagtgt acggtgcgga gttatccggc agacgtttga tccactcttt atcaatccgc
    18421 ccgcgttccg caattgcgtc cacgtcatag gccagagcca gcgtgacaac atcagcttca
    18481 ataccgttga ttaccgacgt cgcttgttta cctgaaccac cgtgtgactg acgaatcacc
    18541 acgttatcac cagtttgctg tttccagtgg gcgctgaatg ccttgttgta ctgttcgtac
    18601 aattcgcgcg ttggatcata tgaaacgtta agaagctgaa tatcctttgc cataacgctg
    18661 gttgccgcca gcaaaaatgt taaccctacg ccccacttgt tcatcgcccg actctcttat
    18721 gttgtgttgt gatgagcaaa gcgtgccaga aggttaacca aacattaaag aataaaaaaa
    18781 gattggctat aacttgtggg tatatgttga gggattaaaa aggcggaaga aatccgcctc
    18841 atattgctga caaagtgcgc tttgtccatg ccggatgcgg cgcgaacgcc ttatccggcc
    18901 tacaaaagtt tgcaaattca ataaattgca gaattcatgt aggcctgata agcgaagcgc
    18961 atcaggcatt tttgcttctg tcatcggttt cagggtaaag gaatctgcct ttttccgaaa
    19021 tcattaatac agttttttcg cgcagtccag ccagtcacct ttgaacggac gcttcatgtt
    19081 ttcgatagcg tcgatgatgt cgtggtgaac cagctgttcg ttctggatac ctacacaacg
    19141 accgccgtaa cctgccagca gcagatcgat agcgtaagcg cccatacggg aagccagaat
    19201 acggtcgtaa ggcaccggag aaccaccgcg ctggatgtgg cccagcacag ttgcgcgggt
    19261 ttcacgaccg gtttctttct cgatgaaatg cgccagttcg tcaacatcac acatatgttc
    19321 ggtaatcgcc acgatcgcgt gttttttacc tttcgcgata cccgctttga tttcgtttac
    19381 caggtcttca cggctgaatt caacttccgg aaccacaacg aattcacagc caccggcaat
    19441 ggccgcagcc aacgtcagat cgccacaata acggcccatc acttccacca cggaaatacg
    19501 ctggtgagaa gaagaggtgt cacgcagacg gtcgatcgct tctacaacgg tgctcagcgc
    19561 agtgaagaaa ccgatagtgt agtcagtgcc tttgatgtcg ttgtcgatag tgcccggcag
    19621 accgatgcac gggaagccca tttcggtcag acgcattgca cccatgtagg aaccgtcacc
    19681 gccgataacc accagcgcgt cgatcccacg ttttttcagg ttttcgatag ccacggcgcg
    19741 gatgttctcg tcgcggaatt ccgggaagcg cgcagaaccg aggaacgtac cgccacggtt
    19801 gatcatgtca gaaacgctgt aacggtctag ctgtaccata cggtcttcat acagacccag
    19861 atagccgtca taaatgccca ttacttccag accttctgtc agcgcagaac gaacaacccc
    19921 gcgaattgcg gcgttcatgc ctggcgcatc accgccgctt gtcaacacac cgattttctt
    19981 aatcatgact acctctgaac tttggaatgc aaaataaaat ctgttgccgg aagtcttctt
    20041 gcacatcgaa gtgatccaac gaatgtgcaa atagtataac aatcacttcc tgctgaattg
    20101 attcaggtca ggccaaatgg cggtatttta tacacaaaat gcgggtctgg ctctctttta
    20161 tactgattat gaaagcatag accgtttacc ctccctgggt acgacggaac aggggtcctg
    20221 atggataatt acatccgatc ccggaaaacg ccgtaaaata gcctgctcta cctgatccgc
    20281 caccatatgt gcctgaacca aaggcagaga gtcttccatt tccaaatgaa tctgaataaa
    20341 gcgggtcggc cctgactgcc gcgtgcgaag atcgtgagcg ccgctaacac ccggccagga
    20401 agtcacgata tcaataattt cttgccgttc ctcatcaggc aatgcgcgat ccagtaatga
    20461 ctgtaccgcc tcatatccca tgcgtaacgc gctatataaa atatagatgc cgattcccaa
    20521 tgcaaacaga gcatcggcgc gatgccagcc gtaccaggac aaccccagcg ccagcagaat
    20581 tgcgccgttc atcataacat cagactggta atgtagcata tcagcccgca ccgcctggct
    20641 ttgcgtccgg cgcaccaccc aacgctgaaa cgagacaagg ataatcgtac aaattagcgc
    20701 cacaattgtc acgataaccc cgacgcctgg atctgtcatc ggtgttggag atatcagatg
    20761 ttgaataccc gtcaaaaaca ggaatagtgc cgaaccggag ataaacatac tttgcgccag
    20821 cgccgcgagg gactctgctt taccgtgacc aaacgagtga ttatcgtcgg caggttgcag
    20881 ggaatatcgc accaccagta aattcgtcaa cgacgcgccg atatccacca gcgaatccac
    20941 cagcgcggcg agaatactca ccgacccggt ataccaccat gcaaaaattt taatcagcaa
    21001 tagcaacgaa gccatcgccg tcgcagcaat cgccgcccga ctgaccagcc gtccataaga
    21061 ttgattcata aatactcccg ctatcaactg acgctagtat aacggaagca aatcatctgc
    21121 aatgcattaa gcagcaggca aattgaggat aaaaaaaacc cccacatcat gtgggggaag
    21181 acagggatgg tgtctatggc aaggaaaaca gggtttacta ctgggaacgt gagttgctac
    21241 tactcaatag cttcaacgat gaactttttt gccattgcgt cacgtcacgc aactgctcca
    21301 ttcgttgttg atgtttctcg tttaaaaccg cttgctgctc cggcgttaac aggcgataca
    21361 tttggttgcg gacttttgcc atctcaacct gacgagcaat ttgctcattc gccatttttt
    21421 ctgcctgtgc gcgcacagcg ttttcatcaa aattttctgc ggtgacaagg cgatgcattg
    21481 tctccagttc gctaacatta acaggaggct gttcgtgccg ggcctgttgc ataagatctc
    21541 gcatctgctg acgctgatgt tcggttaaac ttatgccgtc gaacatatgg ctctgcgtac
    21601 tgcgctgcgt aagttcttca cccggatgcc agttatcgcc tgaaccgact tcagcagcgt
    21661 ggcttaatga actgactgcc agcgttgagg ccatgacggc agcggtaact atgcgcatca
    21721 tttgctccca aaatctttct gtcgcgattc aacgatagag agtttacgat tcaggctgca
    21781 aacatgcgtc agggggtgta aaacaacgta aagtcatgga ttagcgacgt ctgatgacgt
    21841 aatttctgcc tcggaggtat ttaaacaatg aataaaatcc tgttagttga tgatgaccga
    21901 gagctgactt ccctattaaa ggagctgctc gagatggaag gcttcaacgt gattgttgcc
    21961 cacgatgggg aacaggcgct tgatcttctg gacgacagca ttgatttact tttgcttgac
    22021 gtaatgatgc cgaagaaaaa tggtatcgac acattaaaag cacttcgcca gacacaccag
    22081 acgcctgtca ttatgttgac ggcgcgcggc agtgaacttg atcgcgttct cggccttgag
    22141 ctgggcgcag atgactatct cccgaaacca tttaatgatc gtgagctggt ggcacgtatt
    22201 cgcgcgatcc tgcgccgttc gcactggagc gagcaacagc aaaacaacga caacggttca
    22261 ccgacactgg aagttgatgc cttagtgctg aatccaggcc gtcaggaagc cagcttcgac
    22321 gggcaaacgc tggagttaac cggcactgag tttaccctgc tctatttgct ggcacagcat
    22381 ctgggtcagg tggtttcccg tgaacattta agccaggaag tgctgggcaa acgcctgacg
    22441 cctttcgacc gcgctatcga tatgcacatt tccaacctgc gtcgtaaact gccggatcgt
    22501 aaagatggtc acccgtggtt taaaaccttg cgtggtcgcg gctatctgat ggtttctgct
    22561 tcatgatagg cagcttaacc gcgcgcatct tcgccatctt ctggctgacg ctggcgctgg
    22621 tgttgatgtt ggttttgatg ttacccaagc tcgattcacg ccagatgacc gagcttctgg
    22681 atagcgaaca gcgtcagggg ctgatgattg agcagcatgt tgaagcggaa ctggcgaacg
    22741 atccgcccaa cgatttaatg tggtggcgac gtctgttccg ggcgattgat aagtgggcac
    22801 cgccaggaca gcgtttgtta ttggtgacca ccgaaggccg cgtgatcggc gctgaacgca
    22861 gcgaaatgca gatcattcgt aactttattg gtcaggccga taacgccgat catccgcaga
    22921 agaaaaagta tggccgcgtg gaactggtcg gtccgttctc cgtgcgtgat ggcgaagata
    22981 attaccaact ttatctgatt cgtccggcca gcagttctca atccgatttc attaacttac
    23041 tgtttgaccg cccgctatta ctgctgattg tcaccatgtt ggtcagtacg ccgctgctgt
    23101 tgtggttggc ctggagtctg gcaaaaccgg cgcgtaagct gaaaaacgct gccgatgaag
    23161 ttgcccaggg aaacttacgc cagcacccgg aacttgaagc ggggccacag gaattccttg
    23221 ccgctggtgc cagttttaac cagatggtca ccgcgctgga gcgcatgatg acctctcagc
    23281 agcgtctgct ttctgatatc tctcacgagc tgcgcacccc gctgacgcgt ctgcaactgg
    23341 gtacggcgtt actgcgccgt cgtagtggtg aaagcaagga actggagcgt attgaaaccg
    23401 aagcgcaacg tctggacagc atgatcaacg atctgttggt gatgtcccgt aatcagcaaa
    23461 aaaacgcgct ggttagcgaa accatcaaag ccaaccagtt gtggagtgaa gtgctggata
    23521 acgcggcgtt cgaagccgag cagatgggca agtcgttgac ggttaacttc ccgcctgggc
    23581 cgtggccgct gtacggcaat ccgaacgccc tggaaagtgc gctggaaaat attgttcgta
    23641 atgctctgcg ttattcccat acgaagattg aagtgggctt tgcggtagat aaagacggta
    23701 tcaccattac ggtggacgac gatggtcctg gcgttagccc ggaagatcgc gaacagattt
    23761 tccgtccgtt ctatcggacc gatgaagcac gcgatcgtga atctggcggt acaggattgg
    23821 ggctggcgat tgttgaaacc gccattcagc agcatcgtgg ctgggtgaag gcagaagaca
    23881 gcccgctggg cggtttacgg ctggtgattt ggttgccgct gtataagcgg agttaaactc
    23941 cgcatttgta ggcaggataa ggcgtttacg ccgcatccgg catttgagca ggatgcctga
    24001 tgcgacgctg atagcgtctt atcaggccta cactccgggg gttattttcc ccacaaccgg
    24061 cgggaaaaat cttcgatctt gccgctcagt cggcgctttt gcatcgtccg cgtccagctt
    24121 ttcgataacc cggcggcgga gagtaaacgg tgatattgat cgtcatcaaa cggcatatgc
    24181 catgcgatgg cggcagcctc ctgcacggtc acatcgctga cacgggaaac caactccagc
    24241 ggcgcgtccg cagacacttt ccctggcgct atcacgctat acaaccaccc caccttacct
    24301 gtgttttgca tcaactgcgc tatatcgctg atatcaaaat ggtaattgag tttatagcaa
    24361 ggcgagcgcg gctggctgac ctgaattaat gcctctcccc agcggaaaat atcgcccata
    24421 taaacattac tttccgtcag gccgtcggtt gagaggtttt caccaaacgc aggcgcaaca
    24481 aacaactccg cctgttccgg aaattcccgc gcccagtaga gataatgctc acgaggataa
    24541 tgacacagcg ctctgtctgg cccgccgtga acctttttct ccgcctgctc gtcaccttcc
    24601 agccccagct ccgtcagcat caactcacca tcaacctgga ttttggcaat tgcgctgggt
    24661 ttgccttcgg gataagcctg aatcttgcct gtgtatacat caaccggata tcgcatctgt
    24721 tccctctcca cgagaaattt ccccattaga ccatatttat tttatgtcag gcgtgctgtt
    24781 ttcgcggtaa gtatccaggc aggaactcaa tagcaaaccg gacgaacgtt agttcatccg
    24841 gctgtgggga ttaaggaagc aggtttattt caccgtacct aaaatttcga ttttcgctgc
    24901 tctggctttg actttacgtg accagataga ggtaagaatt ggcaccagaa tcgaagtcac
    24961 aatgaccgcc gtcgctacca gcgaagttgc tgccggagcc atcggtttaa acgcaggcac
    25021 catttctgca atcagcacag gtgtcgctac cgcggcccct gcggaactgg aagcggcaat
    25081 tccggcagtg ccatcgccac cgccaatcaa tttatcggcg ataatcaacg gaataccggt
    25141 cacgataatt actgccacac ccaacaggat ccccagcaaa ccagtctggg caatcacagt
    25201 caaatcaatg gtattgccca gcgcgaaggc aaagaatgga atcagcgttt gcaccgcttt
    25261 gctgaaaaat tctcgtaatt cagggtcaag gttccccagg gcaaagccca ccaggaacgg
    25321 taatactgcg ccgacgaaaa catgcggttc aaacgaggca atccctgcag tgcccagaat
    25381 aatcatcgtc atgagcggcc cggactccaa cgacatcaac acaaatgccc cagcttcttc
    25441 ttttgtgccg tactgctgca tgatggaagc gtaaagtccg ccattggtca tatccatcgc
    25501 cgccaccagc gccagcgttg aaagtccggc aaagaatcca acttcaacac catgttccgg
    25561 aataatgcgc gaggcaattg ccgcaaccac ccacgcgacg gcaatttttg ttaccaccag
    25621 cgtaccggat ttacgcaata ccgttcccgt cgcgcttaat tttattgacg cccccatgca
    25681 aaaaaaccac accgccagaa tgggcaccgt accggtaatc atcccgttgg tgaatgatcc
    25741 aaaatatttc cccgcccccg gcgagaaggt gtggcacagt gcgccaagga atagcgggac
    25801 gagcatcatc ccccccggga ttttctcaat cgagcgtttt atctgcattt ccatcacctg
    25861 tcggcatatt tttaagggct gatgcgtcat tcctcaatgg agcatcagtg ttgatggaaa
    25921 cgaagataga cattcattta atcaataaaa gtgatcaaaa ccacatcaat tgaaacactg
    25981 ttttattttt atcggatcat tgtttttatt ttgaaattga tcacaaaaaa accaccgccg
    26041 ttggcgatgg ttcatttttt aagctgatat gcggcctata cgcctcattg cagcaggcgg
    26101 caaatgatta ttttttcgcc gcgaaacgcg ccgcagcttc gtcccagttc accacgttcc
    26161 agaactcttt gatgtagtcc gggcggcggt tctggaattt caggtagtaa gcatgttccc
    26221 acacatccag gcccagaatc gggaagccgg aagcgccaga aatagcttca cccatcagcg
    26281 gagaatcctg gttagcagta gaaaccaccg ccagtttatc gcctttcagc accagccatg
    26341 cccagccgga accaaagcgg gaagctgccg ctttttcaaa ttctgctttg aagttatcaa
    26401 cggagccgaa gtcacgttcg atagccgctt tcaggtcacc ctgcagggtg gtgccttttt
    26461 tcagaccttt ccagaacagg ctgtggttag cgtgaccgcc agcgttgttg cgcagtacgg
    26521 ttttcttgtc tgctggcagc tggtccagtt tggtgatcag ctcttcaacc ggcaggttgg
    26581 caaattctgg caggctttcc agcgccgcgt tggcgttgtt tacgtaggtc tgatggtgtt
    26641 tggtgtggtg gatttccatg gtctgcttat cgaagtgcgg ttccagggca tcgtaagcat
    26701 acggcaggga tggcagggta tagctcatat tcatctccag tattgtcggg cggccgattg
    26761 ttaatgccgc gtaagcagtt ggttcattat agttaattaa atgatattga aaatgattat
    26821 caatgccgta cttttcgtaa gggtatggtt ttgcaggaaa atgcccgaga tgtgaagcaa
    26881 atcacccact taatgccgtg attgccagta aatcgacaac ggcggcaaca ggcgaaaggt
    26941 taatcgacag cacgattttt acactcatct cgtcggagat gtgaagcgac gaaaaatgat
    27001 gaggataaga agatgagtaa cgcgattacg atggggatat tttggcattt gatcggcgcg
    27061 gccagtgcag cctgttttta cgctccgttc aaaaaagtaa aaaaatggtc atgggaaacc
    27121 atgtggtcag tcggtgggat tgtttcgtgg attattctgc cgtgggccat cagcgccctg
    27181 ttactaccgg atttctgggc gtattacagc tcgtttagtc tctctacgct gctgcctgtt
    27241 tttctgttcg gcgctatgtg ggggatcggt aatatcaact atggcctgac catgcgttat
    27301 ctcggcctgt cgatgggaat tggcatcgcc attggcatta cgttgattgt cggtacgctg
    27361 atgacgccaa ttatcaacgg caatttcgat gtgctgatta acaccgaagg cggacgcatg
    27421 acgttgctcg gcgttctggt ggcgctgatt ggcgtaggga ttgtgactcg cgccgggcag
    27481 ttgaaagagc gcaaaatggg cattaaagcc gaagagttca acctgaaaaa agggctggtg
    27541 ctggcggtga tgtgcggcat tttctctgcc ggtatgtctt ttgcgatgaa cgccgcaaaa
    27601 ccgatgcatg aagccgctgc cgcactgggc gtcgatccac tgtatgtcgc tctgccaagc
    27661 tatgtcatca tcatgggcgg cggcgcgatc atcaacctcg gtttctgctt cattcgtctg
    27721 gcaaaagtga aggatttgtc gctaaaagcc gacttctcgc tggcaaaacc gctgatcatt
    27781 cacaatgtgt tactctcagc actgggcggg ttgatgtggt atctgcaatt ctttttctat
    27841 gcctggggcc acgcccgcat tccggcgcag tatgactaca tcagttggat gctgcatatg
    27901 agtttctatg tattgtgcgg cggtatcgtc gggctggtgc tgaaagagtg gaacaatgca
    27961 ggtcgccgtc cggtaacggt gttgagcctc ggttgtgtgg tgattattgt cgccgccaac
    28021 atcgtcggca tcggcatggc gaattaatct ttctgcgaat tgagatgacg ccactggctg
    28081 ggcgtcatcc cggtttcccg ggtaaacacc accgaaaaat agttactatc ttcaaagcca
    28141 cattcggtcg aaatatcact gattaacagg cggctatgct ggagaagata ttgcgcatga
    28201 cacactctga cctgccgcag atattgattg atggtcattc cagtctgctg gcgaaattgc
    28261 tgacgcaaaa cgcgctcact gcacgatgcc tcatcacaaa atttatccag cgcaaaggga
    28321 cttttcaggc tagccgccag ccgggtaatc agcttatcca gcaacgtttc gctggatgtt
    28381 ggcggcaacg aatcactggt gtaacgatgg cgattcagca acatcaccaa ctgcccgaac
    28441 agcaactcag ccatttcgtt agcaaacgac acatgctgac tactttcatg ctcaagctga
    28501 ccgataacct gccgcgcctg cgccatcccc acgctaccta agcgccagtg tggttgccct
    28561 gcgctggcgc taaatcccgg aatcgctccc tgccagtcaa gattcagctt cagccgctcc
    28621 gggcaataaa taatattctg caaaaccaga tcgttaacgg aagcgtagga gtgtttatcg
    28681 tcagcatgaa tgtaaaagag atcgccacgg gtaatgcgat aagggcgatc gttgagtaca
    28741 tgcagaccat taccgcgcca gacaatcacc agctcacaaa aatcatgtgt atgttcggca
    28801 aaaacatctt gcggataacg gtcagccaca gcgactgcct gctggtcgct ggcaaaaaaa
    28861 tcatctttga gaagttttaa ctgatgcgcc accgtggcta cctcggccag agaacgaagt
    28921 tgattattcg caatatggcg tacaaatacg ttgagaagat tcgcgttatt gcagaaaacc
    28981 atcccgtccc tgacgaatat cacgcggtga ccagttaaac tctcggcgaa aaagcgtcga
    29041 aaagtggtta ctgtcgctga atccacagcg ataggcgata tcagtaacgc tggcctcgct
    29101 gtggcgtagt agatgtcggg ctttcatcag tcgcaggcgg ttcaggtaac gctgaggcgt
    29161 cagtcccgtt tgctgcttaa gctgccgatg tagcgtacgc agcgaaagag aaaattgctc
    29221 cgccacggca tcccaattca cctcatcggc aaaatggtcc tccagccagg ccagaagcaa
    29281 gttgagacgt gatgcgctgt tttccaggtt ctcctgcaaa ctgcttttac gcagcaagag
    29341 cagtaattgc ataaacaaga tctcgcgact ggcggtcgag ggtaaatcat tttccccttc
    29401 ctgctgttcc atctgtgcaa ccagctgtcg cacctgctgc aatacgctgt ggttaacgcg
    29461 ccagtgggaa ggatactgcc catccagctc ttgtggcagc aactgattca gcccggcgag
    29521 aaactgaaat cgatccggcg agcgatacag cacattagtc agacacagat tatcggtatg
    29581 ttcatacaga tgccgatcat ggtcgcgcac aaaacagacc gtgccaccgg tgatggtata
    29641 gggctgccca ttaaacacat gaatacccgt gccatgttcg acaatcacaa tttcatgaaa
    29701 atcatgatga tgttcaggaa aatccgcctg cgggagccgg ggttctatcg ccacggacgc
    29761 gttaccagac ggaaaaaaat ccacactatg taatacggtc atactggcct cctgatgtcg
    29821 tcaacacggc gaaatagtaa tcacgaggtc aggttcttac cttaaatttt cgacggaaaa
    29881 ccacgtaaaa aacgtcgatt tttcaagata cagcgtgaat tttcaggaaa tgcggtgagc
    29941 atcacatcac cacaattcag caaattgtga acatcatcac gttcatcttt ccctggttgc
    30001 caatggccca ttttcctgtc agtaacgaga aggtcgcgaa ttcaggcgct ttttagactg
    30061 gtcgtaatga aattcagcag gatcacatta tgacctttcg caattgtgtc gccgtcgatc
    30121 tcggcgcatc cagtgggcgc gtgatgctgg cgcgttacga gcgtgaatgc cgcagcctga
    30181 cgctgcgcga aatccatcgt tttaacaatg ggctgcatag tcagaacggc tatgtcacct
    30241 gggatgtgga tagcctggaa agtgccattc gccttggatt aaacaaggtg tgcgaggaag
    30301 ggattcgtat cgatagcatt gggattgata cctggggcgt ggactttgtg ctgctcgacc
    30361 aacagggtca gcgtgtgggc ctgcccgttg cttatcgcga tagccgcacc aatggcctga
    30421 tggcgcaggc acaacaacaa ctcggcaaac gcgatattta tcaacgtagc ggcatccagt
    30481 ttctgccctt caatacgctt tatcagttac gggcgctgac ggagcaacaa cctgaactta
    30541 ttccacacat tgctcacgct ctgctaatgc cggattattt tagttatcgc cttaccggca
    30601 agatgaactg ggagtacacc aacgccacaa ccacgcaact ggtcaatatc aatagcgacg
    30661 actgggacga gtcgctactg gcgtggagcg gtgccaacaa agcctggttt ggtcgcccga
    30721 cgcatccggg taatgtcata ggtcactgga tttgcccgca gggtaatgag attccggtgg
    30781 tcgccgttgc cagccatgat accgccagcg cggttatcgc ctcgccgtta aacggttcac
    30841 gcgccgctta tctctcttct ggtacctggt cattgatggg cttcgaaagc cagacgccat
    30901 ttaccaatga cacggcgctg gcagccaaca tcaccaatga aggcggggcg gaaggtcgct
    30961 atcgggtgct gaaaaatatt atgggcttat ggctgcttca gcgggtgctt caggaacggc
    31021 aaatcaacga tctcccggcg cttatcgccg cgacacaggc acttccggcc tgtcgcttca
    31081 tcatcaatcc caatgacgat cgctttatta atcctgaagc gatgtgcagc gaaattcagg
    31141 ctgcgtgtcg ggaaacggcg caaccgatcc cggaaagtga tgctgaactg gcgcgctgta
    31201 ttttcgacag tctggcgctg ctgtatgccg atgtgttgca tgagctggcg cagctgcgcg
    31261 gtgaagattt ctcgcaactg catattgtcg gcggcggctg ccagaacacg ctgctcaacc
    31321 agctatgcgc cgatgcctgc ggtattcggg tgatcgccgg gcctgttgaa gcctcaacgc
    31381 tcggcaatat cggcatccag ttaatgacgc tggatgaact caacaatgtg gatgatttcc
    31441 gtcaggtcgt cagcaccacc gcgaatctga ccacctttac ccctaatcct gacagtgaaa
    31501 ttgcccacta tgtggcgcag attcactcta cacgacagac aaaggagctt tgcgcatgac
    31561 cactcaactg gaacaggcct gggagctggc gaaacagcgt ttcgcggcgg tggggattga
    31621 tgtcgaggag gcgctgcgcc aacttgatcg tttacccgtt tcaatgcact gctggcaggg
    31681 cgatgatgtt tccggttttg aaaacccgga aggttcgctg accggtggga ttcaagctac
    31741 tggtaattat ccgggcaaag cgcgtaatgc cagtgagcta cgtaccgatc tggaacaggc
    31801 tatgcggctg attccggggc cgaaacggct taatttacat gccatctatc tggaatcaga
    31861 tacgccagtc tcgcgcgatc agatcaaacc agagcacttc aaaaactggg ttgaatgggc
    31921 gaaagccaat cagctcggtc tggattttaa cccctcctgc ttttcgcatc cgctaagcgc
    31981 cgatggcttt acgctttccc atgccgacga cagcattcgc cagttctgga ttgatcactg
    32041 caaagccagc cgtcgcgttt cggcctattt tggcgagcaa ctcggcacac catcggtgat
    32101 gaacatctgg atcccggatg gtatgaaaga tatcaccgtt gaccgtctcg ccccgcgtca
    32161 gcgtctgctg gcagcactgg atgaggtgat cagcgagaag ctaaaccctg cgcaccatat
    32221 cgacgccgtt gagagcaaat tgtttggcat tggcgcagag agctacacgg ttggctccaa
    32281 tgagttttac atggggtatg ccaccagccg ccagactgcg ctgtgcctgg acgccgggca
    32341 cttccacccg actgaagtga tttccgacaa gatttccgcc gccatgctgt atgtgccgca
    32401 gttgctgctg cacgtcagcc gtccggttcg ctgggacagc gatcacgtag tgctgctgga
    32461 tgatgaaacc caggcaattg ccagtgagat tgtgcgtcac gatctgtttg accgggtgca
    32521 tatcggcctt gacttcttcg atgcctctat caaccgcatt gccgcgtggg tcattggtac
    32581 acgcaatatg aaaaaagccc tgctgcgtgc gttgctggaa cctaccgctg agctgcgcaa
    32641 gctggaagcg gcgggcgatt acactgcgcg tctggcactg ctggaagagc agaaatcgtt
    32701 gccgtggcag gcggtctggg aaatgtattg ccaacgtcac gatacgccag caggtagcga
    32761 atggctggag agcgtgcggg cttatgagaa agcgattttg agccagcgtg ggtaaacact
    32821 gccggatgcg gcgcgagcgc cttatccggc ctacaggtcg aatgtccatg cgggctgtca
    32881 ccctcacccc ggccctctcc ctgaaagggc gagggagaaa aacatagcct cgtgcggcaa
    32941 cggagctgaa cactgctccg gacagtcccc tcgcccctac ggggagaggg ttagggtgaa
    33001 gggaacaagc agcaccatgt ctaaacaagg caacctaatt tacaggaaca cagaacatgc
    33061 aaaacattac ccagtcctgg tttgtccagg gaatgatcaa agccaccacc gatgcctggc
    33121 tgaaaggctg ggacgagcgc aacggcggta acctgacgct gcgcctggat gacgccgata
    33181 tcgcgcctta taaagacaac ttccatgcac aaccgcgcta tatcccgctc agccaaccca
    33241 tgcctttact ggcaaataca ccgtttattg tcaccggctc cggcaaattc ttccgtaacg
    33301 tccagcttga tcctgcagct aacttaggcg tcgtaaaagt cgacagcgac ggcgcgggct
    33361 accatattct ctgggggtta accaacgaag ccgttccaac ttctgaactt ccggctcact
    33421 ttctctccca ctgcgagcgc attaaagcca ccaacggtaa agatcgggtg atcatgcact
    33481 gccacgccac caacctgatc gccctcacct atgtactgga aaacgacacc gcggtcttta
    33541 ctcgccaact gtgggaaggc agcaccgagt gtctggtagt gttcccggat ggcgttggca
    33601 ttttgccgtg gatggtgccc ggcacggacg aaatcggcca ggcgaccgca caagagatgc
    33661 aaaaacattc gctggtgttg tggcccttcc acggcgtctt cggcagcggg tcgacgttgg
    33721 atgaaacatt cggtttaatc gacaccgcag aaaaatcagc acaagtatta gtgaaggttt
    33781 attcgatggg cggcatgaaa cagaccatca gccgtgaaga gttgatagcg ctcggcaagc
    33841 gcttcggcgt tacaccacta gctagtgcgc tggcgctgta aggagcaaac atgatccgca
    33901 aagcctttgt catgcaggtt aaccccgacg cccacgaaga gtatcagcgt cggcataacc
    33961 ccatctggcc ggaactggaa gcagtgttga aatctcacgg tgcgcataac tacgccattt
    34021 acctcgacaa agcgcgtaat ctgctgtttg ccacggtaga gattgaatct gaagaacggt
    34081 ggaatgcggt agccagcact gatgtttgcc aacgttggtg gaaatatatg accgatgtta
    34141 tgcccgctaa cccggataac agcccggtga gtagcgagct gcaagaagtg ttttacctgc
    34201 cgtaattgcc caatgtgcca gagatgcctc cggcacaata ttttaaattt cgatttgaaa
    34261 aattaaacat attacatctc ccggtaagtt atatttccct gatacattgt gagtaaatca
    34321 caaaaataat gaataaccca ttaatgattc atgtggttta tttaaataac cattatgtgc
    34381 attactccgc aaatctgacc tttcactctg tctcaaattg tcattgttta ccgacatatc
    34441 gcctctcatc acttaatcgc tccaccatta caattgatta aaatatattt tatggagtcc
    34501 gattaatggc agctcttact gcaagctgta ttgacctgaa tattcagggc aatggcgctt
    34561 attccgttct gaagcagttg gcgacaatag cgttacaaaa cggttttatc accgactcac
    34621 accagttcct gcaaaccctg ctgctgcgcg aaaaaatgca ctctactgga tttggttccg
    34681 gtgtcgccgt gccgcacggt aaaagcgcct gcgttaaaca accgttcgta ttattcgccc
    34741 gcaaagcgca ggctattgac tggaaagcca gcgatggcga agacgtcaat tgctggatct
    34801 gcctcggcgt gccgcaaagc ggcgaagagg atcaggtcaa aatcatcggc acactgtgtc
    34861 gcaaaattat tcacaaggaa tttattcatc aactgcaaca gggcgatacc gaccaggtgc
    34921 ttgccttgtt aaatcaaacc ctcagctcat aaggaagtgg cgatggagtc atccttacgt
    34981 attgtcgcga tcaccaactg ccccgccggg atcgctcaca cctacatggt ggcggaagcc
    35041 ctggaacaga aagcccgttc tctcggtcat accattaaag ttgaaactca aggatcaagc
    35101 ggcgtcgaaa accgcttatc cagcgaagag attgccgctg ccgattacgt cattctcgct
    35161 accgggcgtg gcctgagcgg tgacgatcgc gcgcggtttg ccgggaagaa ggtttatgag
    35221 attgccatct cccaggcgct gaaaaatatc gatcagattt tcagtgaatt accaacaaac
    35281 tcgcatcttt ttgctgcaga tagcggcgtg aagcttggca aacaggaagt gcaaagcggc
    35341 agcgtgatga gccacctgat ggcgggcgtc tctgcggcgc tgccgtttgt catcggcggc
    35401 ggtattctgg tggcgcttgc caacatgctg gtgcagttcg gtttgccata taccgatatg
    35461 tcgaaaggtg cgccgtcgtt tacctgggta gttgaatcca tcggttacct cggcttcacc
    35521 tttatgatcc ccatcatggg cgcttatatt gcctcgtcga ttgccgataa accggctttc
    35581 gctccggcgt ttctggtttg ctatctggcg aacgacaaag cgctgctcag cacccagtcg
    35641 ggtgcgggat tcctcggcgc ggtggtgctg gggctggcga ttggctattt cgtcttctgg
    35701 ttccgcaaag tgcgccttgg caaagcatta caaccgctgc tcggttcaat gctgatcccg
    35761 ttcgttactc tgctggtttt cggcgtgctc acttactacg ttatcgggcc ggtgatgtcc
    35821 gacctcatgg gcgggctgct ccacttcctg aacaccattc ctccatcaat gaagtttgcg
    35881 gcagcgtttc tggtcggtgc gatgctggcg ttcgatatgg gcggccccat caataaaacc
    35941 gcctggttct tctgcttctc actgctggaa aaacacattt atgactggta cgccatcgtc
    36001 ggcgttgtcg cgttgatgcc gcccgtcgcg gcgggtcttg cgacgttcat tgcgcccaaa
    36061 ctgtttaccc gacaggaaaa agaggctgcc agtagtgcca ttgtggtcgg tgccacagtc
    36121 gcaaccgaac cggctattcc ttacgctctg gcagctccgt tgccgatgat taccgccaat
    36181 acgctggcgg gcggcattac cggcgtgctg gtgatcgctt tcggaatcaa acgtctggcg
    36241 cctggtttgg gtatctttga cccgctgatc ggcctgatgt cgccggtagg ttcgttttat
    36301 ctggtgctgg cgattggcct cgcgctgaac atttcattca ttatcgtcct gaaaggattg
    36361 tggttacgcc gcaaagcgaa agccgcgcaa caggagcttg tccatgaaca ttgagttact
    36421 gcaacagttg tgcgaagcca gcgccgtcag cggcgatgaa caggaagttc gcgacatcct
    36481 gataaacacg ctggaacctt gcgttaatga aatcaccttt gatggtctgg gcagctttgt
    36541 tgcccgtaag gggaataaag gtccaaaagt tgccgttgtc gggcatatgg atgaagtcgg
    36601 ctttatggtc acccacatcg acgagagcgg ttttctgcgt tttaccacca ttggcggctg
    36661 gtggaatcag tcgatgctca accaccgggt aaccatacgc acacacaagg gagtgaaaat
    36721 ccctggtgtg attggttccg tcgcgcctca tgcgttaacg gaaaagcaaa agcaacaacc
    36781 gctgtcattt gatgagatgt tcattgatat tggcgcgaac agtcgcgatg aggtggaaaa
    36841 acgcggtgtg gcgatgggcg attttattag cccggaagcc aattttgcct gctggggcga
    36901 agataaagtg gtcggcaagg cgctggataa ccgcatcggc tgcgcaatga tggctgaact
    36961 attgcagacg gtgaataatc ccgaaattac gctgtatggc gtcggcagcg tggaagaaga
    37021 agttgggcta cgcggggcac aaacctcggc ggaacacatt aaaccggatg tagtgatcgt
    37081 gctggatacc gctgtcgcag gcgatgttcc gggcattgat aacattaaat acccgctgaa
    37141 actgggccag gggccggggc tgatgctgtt tgacaagcgc tacttcccca accagaaact
    37201 ggtagcagcg ttaaaaagct gtgccgcaca taacgattta ccgctgcaat tttccaccat
    37261 gaaaaccggt gcgacggatg gcgggcgcta caacgtgatg ggcggcgggc gtccggttgt
    37321 tgcgctgtgc ctgccaaccc gctatctgca cgctaacagc ggtatgattt caaaagccga
    37381 ttacgatgct ctgctcacgt tgatacggga ttttctgacc accttaaccg cggagaaagt
    37441 caacgcgttt agccagttcc gtcaggtgga ttaatgctaa acgaacgcca gttaaagatt
    37501 gtcgatctgc tggagcaaca gccgcgcacg cctggtgagc tggcgcaaca gactggcgtt
    37561 tcaggcagga ccatcctgcg tgatattgac tatctcaact ttacccttaa cggcaaagcc
    37621 cgcatttccg ccagtggtag tgcgggctat cagctggaaa tcttcgagcg ccgcagcttt
    37681 tttcagttgc tgcaaaagca cgataacgac gatcggctgc tggcactgtt attactgaat
    37741 acctttactc cccgtgcgca actcgcctcg gcgcttaatt tgccagaaac gtgggtcgca
    37801 gagcgtctgc cccggttaaa acagcgttat gaacgcactt gttgcctggc cagccgccct
    37861 ggtttgggcc atttcattga tgagacagaa gagaaacgcg ttatcttgct ggcgaacttg
    37921 ctgcgcaaag atccgttttt aattccgctg gcgggcgtaa cacgagacaa ccttcagcat
    37981 ttatccacgg cctgcgacaa ccaacaccgc tggccgctca tgcagggtga ttatctctcc
    38041 agcctgattc tggcgattta cgccctgcgt aatcaactga ccgatgagtg gccgcaatat
    38101 cccggtgacg agataaaaca aatcgttgaa catagcggtc tgtttcttgg tgataacgct
    38161 gtaagaaccc tgacaggttt gatagagaaa cagcatcagc aagcgcagat aatttctgcc
    38221 gataatgtgc agcggttgct gcaaagggtg ccgggcatcg cgtcattgaa tattattgat
    38281 acgcagctgg ttgagaacat taccgggcat ttattacgtt gccttgccgc accggtgtgg
    38341 attgctgagc accgccaaag cagcatgaat aacctgaaag ccgcctggcc tgcggccttt
    38401 gatatgagtc tgcactttat tacgctactg cgtgaacagc tcgatattcc ccttttcgac
    38461 agcgatctga tcggtttgta ttttgcctgt gcgctggaac ggcatcaaaa cgaacgccag
    38521 ccgatcattt tgctctcgga ccagaacgcg attgccacta ttaatcagct cgccattgag
    38581 cgcgatgttt tacattgtcg ggtgattatt gcccgtagct taagcgaact tgttgccatt
    38641 cgcgaagaga ttgagccgtt attgatcatt aacaacagcc attatttact ggatgacgcg
    38701 gtaaataatt acatcaccgt aaaaaatatc attacggctg ccggtatcga acaaataaaa
    38761 cattttctgg cgacggcatt tattcgccaa cagccggagc gttttttctc tgcccccgga
    38821 agttttcatt attcgaatgt acgcggtgaa agctggcaac atattacccg gcaaatttgt
    38881 gcgcaattag tggcacaaca ccatattacc gccgatgaag cacaacgcat catcgcccgc
    38941 gaaggcgaag gtgaaaacct gattgttaat cgcctcgcca tcccacattg ctggagcgaa
    39001 caggagcgac gttttcgtgg attttttatt accctcgccc aaccagttga ggtgaataac
    39061 gaagtcatta accatgtctt gatcgcctgc gccgccgccg atgcgcgtca tgagctaaaa
    39121 atatttagct atctggcaag cgtattgtgt cagcatccgg cagaggttat tgccgggtta
    39181 acaggatatg aggcatttat ggagttactt cacaaggggt gaactgtgtc ggatgcgccg
    39241 catccgacac tgcatttatc atcaaaaacg tttaacgcag gctattatag tcatcaacca
    39301 tttcgttgta ctcgcgtaat gctctcggga aagagtcttc gaccatccag cttgagtttg
    39361 cgtcctgaag ttgctcttta tcccagtcag agtacgggac tttatctctg atgcggcgaa
    39421 cgtatttttt agcctcgagt tgatactggc ctgccgaatt aataaacgag aaattcatgc
    39481 cgcctttatc cgcttctttg gcctgcgcca ctagcgtttc cagttcagac actttcttca
    39541 ttgccgcatc aacatcaaac ttctcttgcg atatcaggtt attaatttgt ttcgctgaaa
    39601 tcatgactgc cagagagtag tagtggaatg ttttcccttc tctttcttca atatttttca
    39661 gttccgcaag ctggcgctta tcgttaattt cctgaatcgc cgcatgataa gattctgcta
    39721 caggttcaaa ggcttccaga ttttttaaga atgtctggtg cagcgttttc cctttcgcaa
    39781 acgcatcgtc tttataattt tcctgggtgt aatatttatc catttcgtta atggtattac
    39841 ccaacgccac ggcagcatcg atataactca ccgccacgcc atcaattggt tgcagcgcag
    39901 gcgttaacgc cacagcactt tttacgcctt tttcacactc agcgaggttg gattcactaa
    39961 tgccgtagat gccataaaca gtacgctctt caccggtagg cccctgttta aaatctttca
    40021 gccagtcagc ataacgcgcc agactgctct gtacagggat ctgtaacttg ttatagcact
    40081 tgatatagac atccattttt tcgtcgaaaa ccgcttgttc atcgaccacc ggttgcgcag
    40141 gtgtttcagg tttagcttct gcttttgcaa cgggagcttc aggagctggt gcggcaggtt
    40201 gactattggc aggcgggggc gtttctgttt cggctttttt atcatcacaa cccgtcagac
    40261 cgagggccat gatggcgact ataatagcgg aagataataa attcctt
//
LOCUS       DAZUDJ010000043        39354 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.043, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000043 DAZUDJ010000000
VERSION     DAZUDJ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39354
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.043"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(78..1082)
                     /gene="argF"
                     /locus_tag="ACHY1N_002982"
     CDS             complement(78..1082)
                     /gene="argF"
                     /locus_tag="ACHY1N_002982"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFS4045264.1"
                     /translation="MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLT
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYD
                     GIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTED
                     VAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLP
                     AFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
                     "
     gene            1244..1660
                     /gene="rraB"
                     /locus_tag="ACHY1N_002983"
     CDS             1244..1660
                     /gene="rraB"
                     /locus_tag="ACHY1N_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HFS4045265.1"
                     /translation="MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLE
                     TLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAE
                     KFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH"
     gene            complement(1706..2209)
                     /gene="yjgM"
                     /locus_tag="ACHY1N_002984"
     CDS             complement(1706..2209)
                     /gene="yjgM"
                     /locus_tag="ACHY1N_002984"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4045266.1"
                     /translation="MNNIAPQSPVMRRLTQQDNPAIARVIRQVSAEYGLTADKGYTVA
                     DPNLDELYQVYSQPGHAYWVVEYDGEVVGGGGIAPLTGSQSDICELQKMYFLPAIRGK
                     GLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIGLYEHLGFQHIDYALGCTGHVDCE
                     VRMLREL"
     gene            2402..3598
                     /gene="yjgN"
                     /locus_tag="ACHY1N_002985"
     CDS             2402..3598
                     /gene="yjgN"
                     /locus_tag="ACHY1N_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709944.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjgN family protein"
                     /protein_id="HFS4045267.1"
                     /translation="MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLP
                     WALMKCKRYLYANMEVNGQRFSYGITGGNVFVSCLVFVFCYFAILMTVSADMPLVGCV
                     LTLLLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSMKGFWWVTFFLPILMAIGMGTV
                     FFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFK
                     VKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQ
                     RKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCAL
                     VVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLARISRGIM
                     PSLPFL"
     gene            complement(3654..6509)
                     /gene="valS"
                     /locus_tag="ACHY1N_002986"
     CDS             complement(3654..6509)
                     /gene="valS"
                     /locus_tag="ACHY1N_002986"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFS4045268.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQK
                     LERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRN
                     EDEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFN
                     QTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVL
                     PADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEG
                     FVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL"
     gene            complement(6509..6952)
                     /gene="holC"
                     /locus_tag="ACHY1N_002987"
     CDS             complement(6509..6952)
                     /gene="holC"
                     /locus_tag="ACHY1N_002987"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HFS4045269.1"
                     /translation="MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACE
                     DEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK"
     gene            complement(7086..8597)
                     /gene="pepA"
                     /locus_tag="ACHY1N_002988"
     CDS             complement(7086..8597)
                     /gene="pepA"
                     /locus_tag="ACHY1N_002988"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0019538 - protein metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HFS4045270.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE"
     gene            8751..8801
                     /gene="ytgA"
                     /locus_tag="ACHY1N_002989"
     CDS             8751..8801
                     /gene="ytgA"
                     /locus_tag="ACHY1N_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YtgA"
                     /protein_id="HFS4045271.1"
                     /translation="MSIIILATISTTQENK"
     gene            8864..9964
                     /gene="lptF"
                     /locus_tag="ACHY1N_002990"
     CDS             8864..9964
                     /gene="lptF"
                     /locus_tag="ACHY1N_002990"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HFS4045272.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTAL
                     LRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTV
                     NLIYLALAIVLNLWDTVPVRRLRASFSRKGAV"
     gene            9964..11046
                     /gene="lptG"
                     /locus_tag="ACHY1N_002991"
     CDS             9964..11046
                     /gene="lptG"
                     /locus_tag="ACHY1N_002991"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313266.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HFS4045273.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIIGALLPSASFFLISLWLLMRKS"
     gene            complement(11165..12667)
                     /gene="yjgR"
                     /locus_tag="ACHY1N_002992"
     CDS             complement(11165..12667)
                     /gene="yjgR"
                     /locus_tag="ACHY1N_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase HerA-like C-terminal domain-containing
                     protein"
                     /protein_id="HFS4045274.1"
                     /translation="MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLA
                     ESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLTRLKNIGVNDWQPHANPVVVWDIFG
                     EKGHSVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQY
                     IGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDTNGKG
                     VINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAP
                     QVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAV
                     KAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTE
                     DERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASTEQQKNPPTKGKEVAVDDGILG
                     GLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR"
     gene            complement(12797..13816)
                     /gene="ahr"
                     /locus_tag="ACHY1N_002993"
     CDS             complement(12797..13816)
                     /gene="ahr"
                     /locus_tag="ACHY1N_002993"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase Ahr"
                     /protein_id="HFS4045275.1"
                     /translation="MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSD
                     LSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDAC
                     ISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKP
                     LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVN
                     SRDPQALKALAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLI
                     AGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIKHVRDGKARYRVV
                     LKADF"
     gene            14012..14096
                     /locus_tag="ACHY1N_002994"
     tRNA            14012..14096
                     /locus_tag="ACHY1N_002994"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14046..14048,aa:Leu,seq:caa)
     gene            14283..15527
                     /locus_tag="ACHY1N_002995"
     CDS             14283..15527
                     /locus_tag="ACHY1N_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001218945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4045276.1"
                     /translation="MALTDIKVRTAKPTDKQYKLTDGNGMHLLVHPNGSKYWRLQYRF
                     GGKQKMLALGVYPDVSLADARARRDDARKLLANGIDPGDKKKNDKIEQEEARTFEQLA
                     IEWHATNKKWSEEHSRRVLKSLEDNLFPAIGKRNIADLKTRDLLAPIKAVELSGRLEV
                     ASRLQQRTTAIMRYAVQSGLLDYNPAQEMVGAVASNNRQHRPALQLKLIPELLRRIDS
                     YTGRPLTRLAVELTLLVFIRSSELRFARWSEIDFETSMWTIPAEREAIEGVKHSQRGS
                     KMRTPHLVPLSHQALAILKDVYKLSGDRDFVFIGDHDHRKPMSENTVNKALRVMGYDT
                     KVEVCGHGFRTMACSSLIESGLWSRDAVERQMSHMERSSVRAAYIHKAEHLDERRLML
                     QWWADFLDANRESEVSPYDFGK"
     gene            16067..16918
                     /locus_tag="ACHY1N_002996"
     CDS             16067..16918
                     /locus_tag="ACHY1N_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045277.1"
                     /translation="MLVNSWCNALNEAISTSATVCAEDLYKGGHWATAKAILDDYPID
                     LWILSAGLGLLHHKDNVVPYKATFAVGYDESIPLYSQEYVGKSFHRTWWKEITNRSIF
                     KSKHPTSIVELMKKRKRDYYIICGSPDYINAIELDIINGLEYLVDAKKQLLIITSKKI
                     NGRLTTYLFKTNQNMAQWLRCNMLMLNISVAKYIVKEFTSKQLNDLNELSQKLKEELK
                     ELPEREVKKGIRRSPEEVKSFILKIMEKNPGISATHALREFRDSGNSFEEKRFRAEFM
                     ALREAKP"
     gene            16992..18242
                     /gene="dpdA"
                     /locus_tag="ACHY1N_002997"
     CDS             16992..18242
                     /gene="dpdA"
                     /locus_tag="ACHY1N_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-guanine transglycosylase DpdA"
                     /protein_id="HFS4045278.1"
                     /translation="MSKLKYFFPDSQDFIDPSFDFFRETRNEHRVRQRDDQYPHEVFP
                     HPYDGMLVSKAVVDGLGGGESKYTRAQRLRYFRNGMKHFFRLPENMETMGDCGAFTYV
                     NQDVPPYRVEEVIEFYETSRFNHGVSLDHIVFGYEKPGEVFSGEVLTECRRRQDITLT
                     LAQEFLNKSQKSCFTPFGVAHGWSKTSYRQSVEALLAMGYKNITMGGMVPLKTAQILE
                     TLEEIKPLLKSDTRVHLLGIARPESFSDFIKFGVTSIDSTTPLQQAFKDRKNNYHTLD
                     GPAYTAVRVPQFDANPSLSRKIKSGVIDQDIARHLEKDAMNALFEYDKGALSLEKALD
                     AVLAYERLHSGEKEADKIRADYERTLGERPWKQCQCNICQAIGINVIIFRGAERNRRR
                     GFHNIQVLYNRLQHTLSLRSEELS"
     gene            18239..19369
                     /gene="dbpB"
                     /locus_tag="ACHY1N_002998"
     CDS             18239..19369
                     /gene="dbpB"
                     /locus_tag="ACHY1N_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DGQHR domain-containing protein DpdB"
                     /protein_id="HFS4045279.1"
                     /translation="MSEYRVPALRIRQGEERQLYSLAIEGKQISKIAAISRIRRGEES
                     LVGYQRPEVRNHIREIQRYIESANPMIPNPVIIAFDKRVRFEPLTDNDDMGHLVIPFS
                     EDKDFEKPGFIVDGQQRTAALRDAEINSFMMPVSAFIANDAEEQREQFMLVNSTKPLP
                     KTLLYELAPHTHGRLPSDLQMRKFPSLLTQRLNFGEGSLAGRIKTATNPDGVIADNSM
                     IKMIDASLREGALYRFRDPATGLGDEEKMVKLLNNFWSAVETVFTDDWDKKPRYSRLL
                     HGVGILALGSLMDEIDQVHQDYKGEPGWTEIPSYTRFVEELNRIKPLCAWSSGVWNFG
                     TDIDGQPIVRKWNELQNLSKDISLVTDYLVTGYMKTVNADIK"
     gene            19806..22961
                     /gene="dpdE"
                     /locus_tag="ACHY1N_002999"
     CDS             19806..22961
                     /gene="dpdE"
                     /locus_tag="ACHY1N_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpdE"
                     /protein_id="HFS4045280.1"
                     /translation="MPLEVGDLVDSPYGIGKLIRINNNDALIKYFDSPVNYEGIEQTV
                     EVKHLKKAELHAESLVYRYDYEVAHWQIARVVGAVPGGVRLHFPNKQQEDVSLNDIFV
                     RWDRPISDAAALLAERITYTPFWQDARLAYQHQMLKQRNACAGITSSLSSSIELEPYQ
                     LAVARRVLSDPIQRYLLADEVGLGKTIEAGLIVRQHVTENPLAHCVVIVAPGVLHRQW
                     QQELSARFHLEELLNKSIHIIDMAAFSTADPLSFRPDMLVIDEAHQVGAWAWDAEYEQ
                     RYASVNYLAQQSEKLLLLSATPVTGNEKNFLAMLHLLDAKNYPLTDTGLQKFQQRIQQ
                     REEIGSLFYAFNCDNDNMTLEENLEALTRMFPEDEVLNGMASQLLPHLDMMQPLRSEA
                     RDLLINKIRHYIGNRYRLHHRLLRNRRSNPAISVLMPGLSGLSLKKYATTNASNDMMI
                     AWRESAIMMHPQDPTLAAIYQLLFEAAIATPELLARLANYRLQQESLGAAQGFLYSDS
                     QLALLQHPLFDGEKEILLELIDRCKMECDSKRQRLIDVLEKLLDSNVRELPYIVVFCD
                     QPWVADQVFTDLMIPFIGKIQRHNPDKEVRFGKGSKCQILVCDRRAEEGVNLHGGRKI
                     ALHYDLLLSPNRMEQRLGRLNRYCATESATTILSMALVSEAEGLQNQWLTILNEVFDV
                     FEESIASLQYLIDEELQRLISNLYPLGEESMMQLSARLAGEDGRLTVEKQRIEMQEVL
                     LQIDGDIIEAREYADALAEIDENEEEFRRCARNLIGNVLKFDFIPDEKDPSIFRYRFN
                     PGDRGTGTLVSPQRLQKHCLLGFDLNQSSGSSPMTWPLSYYRADTSQGKIRPARLGEP
                     FHDAILQMLDFEERGVASAIIRITPGMGDENIFFRYDFLIEADVHTPALQRLADHLMP
                     PETITLWLDQAGQQVTNAEVLMILNEDYKPKDKGGRHLNLNEERWAQISHCISAKDWR
                     TWCNDSYSIAQRLAVEQFATQQALSLSRLEHYLSSAALHHANRQETGQMLRQGIAQPK
                     MTCLATRALIIASEAILDEDS"
     gene            22967..25534
                     /gene="dpdF"
                     /locus_tag="ACHY1N_003000"
     CDS             22967..25534
                     /gene="dpdF"
                     /locus_tag="ACHY1N_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001512313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpdF"
                     /protein_id="HFS4045281.1"
                     /translation="MNLAQLIDNDFISSRLSECLLPEATAGHLDRRALIRDWLYREKH
                     AHHNDNELTVPDDSQPGWPRQEEWEASGINCQRLGQTFLLSAGPAWCPQWLEQGNGMP
                     FLASDQHQFCRQDTRVPMDYVLRRYFKKDNYISYQAPGQRDAVRRALFAPPGSTLLVN
                     LPTGTGKTLVAQALALTASAPGALCVLIAPTTALVLELASRFRKLLIEAGNKAESVTG
                     WYSGLPAQDKYDTYMRIRVGEQRLIVTSPEATCSSLQFALFEAAKQGGLRHVIVDEAH
                     IVASWGNDFRPHFQQLGGLIRGLKRVSREANLTPCSTLLMSATITEASRKILRDTFDQ
                     EMSELHACHLRPEPAYWCYRAKDHSDKRDKVLQSLAHAPRPLILYVTRPKEAEEWAQQ
                     LRLQGYQRLATFTGDTPSEVRRSLLEKWDKNQLDIMIATSAFGVGMDKNDVRTVIHAT
                     VPENMDRFYQEVGRGGRDGYACTSLLIYNHQDVKQAEHLSSQKLIGLELGLERWKKLW
                     GSAESVGDNLYRIDIERIHSGLNFRSKQNKLWNLRTVLMMVRAGVLELDADLQNPPDK
                     KDFADVNRYEAAKEQIIRQNGNSLVVRILRSHHTGEELWKTRIIPSREETLQAARANH
                     NALINWLHTPLSRPLCEALVDLYSMAEFIPGHACGGCPACRDNQALTSNYPSPPTLLL
                     NPPASVAQQALSRWQALSGLSYSSCFITYPPVNDDEWERENWYHRIATLLVQLYHRGI
                     VQRVWADPALLHSIFSAIPRGERLILLSDELPARDEPAPDNDVMAELAELVLPTQESC
                     ANGYLPPFNPAPLQLTLIPHDMPDPHHPGGAHYVLLDNHNWITIEQLQRKLDSVDYQ"
     gene            25518..26423
                     /gene="dpdG"
                     /locus_tag="ACHY1N_003001"
     CDS             25518..26423
                     /gene="dpdG"
                     /locus_tag="ACHY1N_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpdG"
                     /protein_id="HFS4045282.1"
                     /translation="MSIINNAHGGSQYAVLAAFYQVLKASPKNQLPREKLMALCAPET
                     LQTGDSQNARGKASQELRAWLDLGLLTEEKVEETTQISFNANYFSTKSMPLRQAARRC
                     LQAQENNSDLSSRDERAVDLTLLAALLLALDVYQNAEIKSGNLEVLVNTFIPDFRINS
                     NEIAVVPGYLSWLGFAQQLTRDSYAIDPTDSIREELPFLMRVGEQLSIGEVLQRLNRA
                     LPVLDGGSYRQQVEERISLYGWHSLSPNRLSTSLSRALLRLQLSGVINMKAESDASGA
                     MQLTGRNGSVLRTVTHLTLNDVGVH"
     gene            26423..29479
                     /gene="dpdH"
                     /locus_tag="ACHY1N_003002"
     CDS             26423..29479
                     /gene="dpdH"
                     /locus_tag="ACHY1N_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001512314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpdH"
                     /protein_id="HFS4045283.1"
                     /translation="MPQLQSYWPSEQNVTACILTEAESLADSQLLAVHEPMRLDRIEF
                     QSGKVTQVGEGALLDFLLEHNRPLPLIGASGVGKSHLVRWVHAQLKRREDHAKYHIIR
                     IPKNASLPRVLAAILEGLDGEEYQSIREKVNGVGKQLIPENVAEHIALKLRQALNAAY
                     TDAIEELRQEKMGKIQLEESRKKQLEEIQQHAASSRLPALFFDSVMTQYFTAPGACLH
                     NIAQRFCQGANDDSIANLRYEMSAEDFTFKGLDFRQVSPTVLPYLRNQQLLTSDEKKQ
                     AAARVVNVVRSQALEDTFVELFSFNRANFQDLMRMIRRQLLAEGRDLILLVEDLTATS
                     AIEDVLIACLIEEDEYDGKKVLCTLRSIIAVTEGHDSFKRLRNTLGTRARYEWVIQQH
                     ASENDVALKKRVIDFCGRYLNAARHGAAALETYHLQQDAQCYQEIPVWQDQEVLENES
                     AAPALASFGSSSIGHPLFPFNPAAIGQLVERHCKVKEQGLVFIPRNILHEILREPLKK
                     YRQNYLDGQFPPSQFAEIVCNPALQQRVRLEGLSQPERINSLLAVWGGNSTNLAGLTP
                     AICKEFGLPDAAVLLGGGGTPPEPAPEPVPEPAPVPESVPAPPSPLDEWKLVLDKWHQ
                     SKTLEQTRARDIRKWLLEALNARIDWSTELIQTSLMASSAKTQGRIHLPGVLVGNQSH
                     PLVKLEDTPELRSACLAMAHFNHYQSWDYDGSEIDYAAFHSFMDCIEHEVKLKVLQEE
                     REELSSIINDLQLSGAFLGLDGLSASHPATLVQALLTEPQVANSNHPLLDEFLTQARD
                     TVIDEHLKRRERLIALTAAKKPGAQPYAINGLMLVEASKKQSPDAGKQPGKIHEVKSK
                     LGGYRTLLLKTQESITERLSDGNSASLAAVNLCDTMKEIVELANSADVARPMGETVPV
                     LLKLLKSWKDPELKKLIRQLEKLTLPADNSHMLMREILAINGEQFEAFRQLLENWGKF
                     EDATDKYVQQRISDKGGDQVEDAENQVTDTLANLAEQLTLLEADLS"
     gene            29476..30267
                     /locus_tag="ACHY1N_003003"
     CDS             29476..30267
                     /locus_tag="ACHY1N_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045284.1"
                     /translation="MSEVNINDVVTPVASVPEERGIFARRSGDFKARLQRYQQMEKAQ
                     DIRDNLLRIAKKIDTPTQTLAQALCSYRVLRQVHDDETGKPIVGPFDRATFGNPQILL
                     TAFCQQYATHKHDVEQEGELALLTQEIRRLASELSTHTTAAWVNYIRGLKAQWEVDQR
                     LFSNLAHQEGQRKVQQHYIDLVEKFTSSSRGLPKTIEEFETVRDLHEKLCQQRGALKL
                     DVPEEVNHFLKAVAGQGATLDMLTPNVLSWLTEEDDPTRYRIRRL"
     gene            30283..34812
                     /gene="dpdJ"
                     /locus_tag="ACHY1N_003004"
     CDS             30283..34812
                     /gene="dpdJ"
                     /locus_tag="ACHY1N_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpdJ"
                     /protein_id="HFS4045285.1"
                     /translation="MEQIIRAVLDGLESQEAVLLTWGNTQGFFTETELRNTISQVLQN
                     HPLDANGLTSFGIVKVMIDRGLLLRHQQNGVSVFRTRMAESVRLYSQLRQMFPKHGFN
                     DNWRTAPTLVSDYRFLRRQRKYPKRDRQAAEVLQQLDEIAGFTSTHRQLLSALLSHSS
                     GMYNLAYFQQEACKNVLRGLQQSQHRSTATIVCAGTGTGKTLAFYLPALTFIGSELVA
                     KRKDAVKALAIYPRNELLKDQFIETLRQTRKLNTELAKKGVRKVRIAALFGMVPTNKE
                     AIHRDYMKDAWCRHRNGMACLYIPCPTESCRGKMVWHTADYDKNLERLHCDSCSQTIE
                     PDEVILTRKRMKIELPDILFTSTEMLNKQMGNPFLASLFGIGKNVVPPSMMLLDEVHT
                     YSGVSGAQNGMLIRRWRHLSGATPHFVGLSATLEQATRFMASLTGLEEYLVAEVSPIE
                     DDMETEGAEYMLALRGDPASRSSLLSTTIQASMLTRRMLDNAAVPVSNGMYGTRSFVF
                     TDDIDVINRLYFQLLDAEGRYSNGNINAKKEPLAMLRGDAPNEEKFTFGQQWPLAKMI
                     GHTLDSADRSNVKRTSSQDAGVDHAADLIVATASLEVGFNDPNVGAVIQHKAPRDNAQ
                     FLQRKGRAGRQRTMRPWTVVVLSDYGRDRMAFQCYENLFEPVLKARQLPVGNSYVLRM
                     QAAFATMDWLSSRNEYLNQWNRGIWDDLSVPQDKGKPSEAQSKLADLIEDLLNSQKIQ
                     QEFNSWLAEALGIKDEKLLQSLLWQPPRAIMTAFLPTVLRRLRSNWSRLGIEQADNCR
                     KSTPMPDFIPSALFNDLCLPELQINLLGEVGQEPDAHSMPILQGMKDFAPGRISKRFA
                     IKNIRECHWLVPKKLELKDGSHPFPIDDYCPPDKRESMPDCHITTRTGMQVIPCFRAW
                     EVTASTPPDDLKLSETSNAFLNWHSEIRPPQNGIPAEVPSNNAWQDIFQQVEFYSHQQ
                     HCPIEAVRFATGSRANIKFSDQREDLQIDFKFEHQGEPAAFGFSLWVDAIKFQCRLPN
                     FDLASISNNRELVAGLRTARFLYEVSHDEAISVNTFLGGWLAETVLAGIGSEAVLKNC
                     TPEQAFRAMEHNSARIALIDVPARIFQTLYDAQTGEEIEQDLQQSLRELLSQAPVMAR
                     IADWVELLWQPLDNTWLEWLTLNFTNTLGAALLQTAMQLCPDADDNDLILDLNGGPVR
                     TSLLAPDQREIWLSETTVGGGGIIEKIQQIYREDPRSFFELLDFNLSPGDYETMDNNV
                     WHLLQTMVNPTSSLPACMNEMRLANDHASQVQAQRNLLGELQRSGFMTSHSFLSAINT
                     RLLRPGTDASSDVFLLQLQQDWRQQEQRLGIELPQRVYAFTCSQSSALDQQLQQASQG
                     QHNLESWRLNTCNGLLWPRGHTIRDSWLTWYNPYSFAGPTERLLLAHVVQHSCAQVAL
                     SQPDWMQQCHQHLENNGKCELLAEPGDAINEAIATLLVTPVEMYGLFFYPRVSALRRH
                     NNDTFAMIEIPEAIQ"
     gene            34809..35351
                     /gene="dpdK"
                     /locus_tag="ACHY1N_003005"
     CDS             34809..35351
                     /gene="dpdK"
                     /locus_tag="ACHY1N_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009114670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D-like domain-containing protein
                     DpdK"
                     /protein_id="HFS4045286.1"
                     /translation="MNTRRIFKSRTSRQSEVLDVLSSLLVAEIAQPSAELWIVSPWIT
                     DLDLLDNRTGRFDYLEPAWGQRQVQTSELLARAVANGGTLKVMTNETQHNARFIRQLT
                     ERVANYGMLDNLYIGQKEVLHTKGFLGDHFFLSGSMNLTIGGIVINDEQINLTTDKTA
                     IVQALLAFNDFYQPAQGGVQ"
     gene            35348..37603
                     /gene="dpdD"
                     /locus_tag="ACHY1N_003006"
     CDS             35348..37603
                     /gene="dpdD"
                     /locus_tag="ACHY1N_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpdD"
                     /protein_id="HFS4045287.1"
                     /translation="MNSADSEKFLRAFFHRENNIISWEKIAGGLLEASTQQRLTPWLD
                     DVRNGCFPVILPRVVKGSNDKVTWYAMADEERDYAELRELLDAHVGTSWSDFNRQRTM
                     LDPSDPVEKALIDHYSDRVYKFSSLSLSRIPEIFNGIERLRQQLASRPSYQLTLLRPR
                     GRILRDIRAALRRRDVPQTRLYLQELREAGGIGHINELFIELRCMALEGDAKSLLDST
                     QLRQVLDMPHPLVLAEEVMTVFYQQFLLKYEQLSDLAAQRQAFNNLLVKNVPRLFQVT
                     QGINTPSAIKNILLWLLSDTQSDPARLREQAQQVVAGMKGATDDDRHWIRRLLEAFPT
                     VAVASPPTASIDELLARADEYPESVLKELLLLPVSARGVAIALQCAWVVGSAGAAVSA
                     VSYLQQLAQQERDLLLAKPAFQRYYTALQLMLPSKRTEHDTAGINNWQDWLKEVLNNP
                     QWSGAIEAVEQACGQWNAAAFQPEAFVSLLDKTNNCASMVLRDAIPVLLEWLDNHQTS
                     ASWQSVRLALLQQLALDDNSSREDIFTACELARGYLEGDSNAHDYRELIENLQMMIES
                     SGTTSASAWLDLLELFLVYPTADQLAREQLFNLVLNMFYRNPARYSELQWSLLAQFAG
                     ECGLVCEIPPQILEDSGEKNDEVRVGSTLNDKVVGIYTLTESVAQRVKKQLLADYPQA
                     DIRLNNDKGGSTMLRSLAREADVFIFAWLSSKHSAYYAIKEERGDKPLLQPSGKGSTS
                     MLDCIRSYLKL"
     gene            complement(37660..38022)
                     /gene="queD"
                     /locus_tag="ACHY1N_003007"
     CDS             complement(37660..38022)
                     /gene="queD"
                     /locus_tag="ACHY1N_003007"
                     /EC_number="4.1.2.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HFS4045288.1"
                     /translation="MKTTLYKDFTFEAAHRLPNVPEGHKCGRLHGHSFVVRLEITGEV
                     DKHTGWIIDFAELKAIFKPTLDRLDHYYLNDIPGLENPTSEVLAKWIWNQVKTQLPIL
                     SAVMVKETCSAGCVYRGE"
     gene            complement(38322..38614)
                     /locus_tag="ACHY1N_003008"
                     /pseudo
     CDS             complement(38322..38614)
                     /locus_tag="ACHY1N_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001616552.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
     gene            complement(38785..>39354)
                     /locus_tag="ACHY1N_003009"
     CDS             complement(38785..>39354)
                     /locus_tag="ACHY1N_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HFS4045289.1"
                     /translation="NNQRWEPDWFLQSLLNNHIDKMVERYSCLRAFRTDLFYQDHTAK
                     FFLQDHQQLEWDIRKLMNRMMQLEAVVGFFWVIEWTEDHHYHAHVVFWLDGSKTQNTY
                     TWAQQAGLYWSDITDREGWYHRCEFKEHYEANINIPVRYSDPDSITNIRQVLAYMTKI
                     QQKHGLLLYGCNEVPARPLTGRPRSSQSL"
BASE COUNT         9700 a         9912 c        10072 g         9670 t
ORIGIN      
        1 aattgaacta ttactgcata aaataatgtg atgccgggat gtttttgtat ttcccggcat
       61 ctttatagcg atatcaatta tttactgagc gtcgcgacca tcaccgcttt gatggtatgc
      121 atgcggtttt ccgcctgatc aaaaacaatg ctggcggcag attcgaagac ctcatcagtc
      181 acttccattc cgccatgtag gccaaactct tccgccattt tcttaccaag cgtcgtctgg
      241 tcgtcatgaa acgcgggcag gcagtggagg aatttgacct ccgggttacc ggtcaactgc
      301 atcatcttgc tgttcacctg ataatcacgc agtaatgcaa tccgttctgc ccatttctct
      361 tttgcttccc ccatcgacac ccatacatcg gtatagataa agtcagcacc ttcaactcct
      421 ttggctacat cttccgtcag cgtaatattc ccgccatttt gctgtgccag ggcgcggcat
      481 tccgtaacca gcgcagcttc cggccagcat gcctgtggcg cgaccagacg caaatccaga
      541 ccggtaagcg ccgcagcttc gagcatcgaa ttgcccatgt tgttacgtgc gtcacctgca
      601 tagaccagcg tcatttcgtt gaatgcttta ccgggtaaat gctcctgcat ggtgaggaga
      661 tccgccagca actgcgtggg gtgaaactca ttggtcaggc cgttccatac cggcacgcca
      721 gcgtattccg ccagtgtttc gacaatctcc tgaccatagc cgcgatactg aataccgtca
      781 tacatgcgac ccagcacgcg ggcagtgtct ttaatcgact ctttatgacc aatctgactg
      841 ccgcttgggc cgagataagt aacgcgagca ccctggtcat atgcggcaac ttcgaaagag
      901 catcgggtac gggtcgagtc tttttcgaag atgagcgcga tgtttttacc agtgagtttg
      961 gcttcttctt tgccgctttt cttatcggct ttcagcttcg cggctaactg cagcaggctg
     1021 ttgagttcag ctggcgtgaa atcgagtaat ttcaggaaat gcttatgata aaacccggac
     1081 atagatccct cctgtggcta acgccttaat gaattaaaat tcaatttata tggatgatta
     1141 ttcatttgca agtctaaagc ataaatcttt gtcacaaagg tggaggcaat gtcagtggtg
     1201 tgtgacaata agagtatcgg caggacatta agaggaatga gccatggcaa acccggaaca
     1261 actggaagaa cagcgtgaag aaacacgttt gattattgaa gaattactgg aagatggcag
     1321 cgatccggac gcgctgtaca ccatcgaaca ccatctttcc gcagacgatc tggaaaccct
     1381 ggaaaaagca gcagttgaag cgtttaaact cggttacgaa gtgaccgatc cagaagagct
     1441 ggaagttgaa gatggtgata tcgtgatttg ctgcgacatc ctcagcgagt gcgcgttgaa
     1501 tgccgatctg atcgatgccc aggttgaaca actgatgacg ctggcggaga aatttgacgt
     1561 tgagtacgac ggttggggca cttactttga agatcccaat ggcgaagacg gcgacgatga
     1621 agattttgtc gatgaagacg atgacggggt tcgccactaa ttaattgatt aaaatgcccg
     1681 atagcacaca ctagcgggca tttttttaga gttcgcgtag catccgcact tcacaatcta
     1741 catggcccgt gcagccaagt gcatagtcga tatgttgaaa acctaaatgt tcatacaaac
     1801 caatcgcttc tttcaaaaaa gcggtcgttt ccagatagca gcgtttgaag cccatctctc
     1861 gtgcctgctc catcgccatt aaggccagtt ttttcgccag ccctttaccg cgaatagccg
     1921 gaagaaaata catcttctgc agttcgcaaa tgtccgactg actcccggtt aatggcgcaa
     1981 tcccaccgcc gccgaccact tcaccatcgt actcaaccac ccaatatgca tgacccggct
     2041 gactatacac ttgatacaac tcgtccaggt tcggatcggc gacggtgtag cctttatcag
     2101 cggtaagacc gtattcggcg gatacctgac gaatgacgcg ggcgatggcg ggattatcct
     2161 gctgcgtcag gcgacgcatt acaggtgatt gcggcgcaat gttattcata gtttaaccca
     2221 ataaaaataa agtaattata catttgttta ataccactct cttcttacgt gcgcaagcga
     2281 cttataaagt aataaagttt ttgccagcct attactgata agagtattgt aacgtggcag
     2341 aacattttac tgtctgtata tataaattat atcaatggat tttttaattc agggaatttt
     2401 tatggctcaa gttattaatg aaatggatgt tccgtcccat tcgtttgttt ttcatggtac
     2461 aggtgagaga tattttctta tttgtgtggt gaatgtgttg ttaacgatta taacgctagg
     2521 tatctatttg ccatgggcat taatgaaatg taagcgttat ctctatgcta atatggaagt
     2581 taacggacaa cgattttctt atggaattac tggtgggaat gtttttgtta gttgtcttgt
     2641 ttttgttttt tgctatttcg caatcttaat gacagtgtca gcagatatgc cacttgttgg
     2701 ctgtgttttg actttgttac tgttggtttt gcttatattt atggcagcaa aaggactgcg
     2761 ttatcaggcc ttgatgacca gtctcaacgg cgtaagattt agttttaatt gctctatgaa
     2821 agggttctgg tgggtaacct ttttcttgcc gattttaatg gccattggga tggggactgt
     2881 tttctttatc tcgacaaaga tgctacatgc caatagttca agtagtgtta ttatatctgt
     2941 ggttctgatg gcaatagttg gtattgtttc cattggtatt tttaatggta ctttatatag
     3001 cctggtaatg agttttctct ggagcaatac cagtttcggt atacatcgtt tcaaggtgaa
     3061 attagatact acgtattgta taaaatatgc cattctcgca tttttagctt tattaccttt
     3121 tctcgctgtt gctggttata ttatcttcga tcaaatatta aatgcgtatg atagttctgt
     3181 gtatgcaaat gatgatattg agaatttaca gcaatttatg gaaatgcaac gtaaaatgat
     3241 aatcgcgcag ttaatctatt attttgggat tgctgttagc accagttatt taacggtgtc
     3301 gttgcgaaat cattttatga gcaacctgtc actgaatgat gggcgtattc gttttcgctc
     3361 aactttaacg taccacggta tgctttatcg catgtgtgcg ttggtggtga tatccgggat
     3421 tacgggcggt ctggcttatc cactgctgaa aatatggatg attgactggc aggcaaaaaa
     3481 tacgtatttg ctgggcgatt tggatgacct tcctttaatc aataaagaag aacaaccaga
     3541 taaaggcttc ttagccagga tttcacgggg aattatgcct tctttaccat ttctgtaaga
     3601 gataaaaaag gccggagcat gctccggcct tcgttttcat tactgtgttt tgattacagc
     3661 gcggcgataa cagcctgctg ttcaatcagc ttcgctttcg cttctgcata gccttccagc
     3721 ttttcacgct ctttcgcgat gaccgcttcc ggtgcgcggg cgacaaagcc ttcattcgcc
     3781 agcttgttct cgatacggct gatttcacct tcaatcttcg ccacttcttt cgccagacgc
     3841 gccagctcat cttctttgtt gatgaggcca gccatcggga tcagcagctc tgcaccgtcg
     3901 atgatcttag taacggaaac cggacctttg tcatcggcag gcagcacggt gatactttcc
     3961 agacgcgcca gcgtttgcag gaagccacgg ttttcattta cgcgacgttc tgcatccgcg
     4021 ctgcaaccac gcagtagcag ctccagcggt ttgcccggcg cgatgttcat ttctgcacgg
     4081 atgttacgta ccgcaacgat cgcctgcttc agccactcgg tgtcggccag tgcggcttca
     4141 tcaacctgag atgcatcgta ctgcgggaac ggctgcagca tgatggtgtc ggcagtgata
     4201 ccgcaaagta ctttcacacg ctgccagatg gtttcggtga tgaacggaat gatcggatgc
     4261 gcgaggcgca gcagaccttc cagtacagtc accagcgtat ggcgagtacc gcgcagttct
     4321 gcttcggtgc caccgttcat taccggcttg gtcagctcga gataccagtc acagaactgg
     4381 ttccaggtga actcatacag aatgcctgcg gcgatatcga agcggaagct gtccagcgct
     4441 tcgcggtacg ctttgatggt ctggttgaac tccgccagaa tccagcggtc cgccagcgac
     4501 agcgtcattt cgccgccgtt gaagccgcaa tcctgacctt ctgtgttcat cagcacaaag
     4561 cggctggcgt tccacagctt gttacagaag ttacggtaac cttccaggcg cttcatatcc
     4621 cagttgatgt cacgaccggt agacgccagt gccgccaggg tgaagcgcag cgcgtcagta
     4681 ccgtgcggtt caataccgtt cgggaactgc ttctcggtgc gcttacggat tttgtccgcc
     4741 agctgtggct gcatcatatt gccggtgcgt ttttccagca gttctggcag cgaaataccg
     4801 tcaaccatat ccagtgggtc aataacgtta cccttggatt tggacatctt ctggccttcg
     4861 tcgtcacgaa tcaggccggt catgtaaacg gtgtggaacg gcacctgcgg tttgccattt
     4921 tcatctttga tgaagtgcat ggtcatcatg atcatgcggg caatccagaa gaagatgatg
     4981 tcgaagccgg ataccatcac gctggttggg tggaactgac gcagggcgtc ggtgttttcc
     5041 ggccagccta gggtagagaa ggtccacagt gcagaagaga accaggtgtc gagaacgtct
     5101 tcgtcctgac gcagggcaac gtcggcaccg aggttatttt ctttacgcac ttcgtcttcg
     5161 ttgcggccaa cataaacgtt acccgcttcg tcataccatg ccgggatacg gtgaccccac
     5221 cacaactgac gagagataca ccagtcctga atatcgcgca tccaggagaa gtacatgttt
     5281 tcgtactgct tcggtacgaa ctgaatgtcg ccgttctcaa ccgcttcaac tgccggtttc
     5341 gccaggacat cggcacgcac gtaccactgg tcggtcagca ttggttcgat gaccacgccg
     5401 ccacggtcgc cgtaaggaac ggtcaggtca tgtggtttaa tttcttccag caggccgagt
     5461 gcgtcaaccg cagcaacgac cgctttacgt gcagcaaaac gctccagttt ctggaactct
     5521 gcagggattt cgctggaata aacgtcagat tcgttacctt tggtatcgaa cacctgggcg
     5581 ctttcacgga tatcgccgtc aaaggtcagg atgttgatca tcggcagggc gtgacgttta
     5641 cccacttcat agtcgttaaa gtcgtgcgcc ggagtgattt tcacgcagcc ggtgcctttt
     5701 tccatgtcgg cgtgttcgtc gccaacgatc ggaatacgac ggttaaccag cggcagaatg
     5761 acatatttgc caatcagatc tttgtaacgc ggatcttccg ggttaacggc cacgccggta
     5821 tcgcccagca gggtttccgg acgagtagtc gcaaccacca gataatcttt accatctgcg
     5881 gttttcgcgc cgtcagccag cggatagcgg atgtgccaca tcgaaccttt cgattcgcgg
     5941 ttttccactt ccaggtcaga gatagcggtg cgcagtttcg gatcccagtt taccaggcgt
     6001 ttgccacggt aaatcaggtc ttctttatac agacgaacga aaacttcttt caccgcattg
     6061 gacaggcctt cgtccatggt gaagcgttca cgctcccagt ccacggagtt gccgagacgg
     6121 cgcatctgac gggtaatggt gccgccggat tccgctttcc attcccagat tttgtcgatg
     6181 aaagcttcgc ggccgtagtc gtgacgggtt ttaccttctt ctgcggcaat cttgcgctca
     6241 acgaccatct gggtagcgat ccctgcgtgg tcagtaccga cctgccacag ggtgtttttg
     6301 ccctgcatgc gctgatagcg gatcatggta tccatgatgg tttgctggaa ggcgtgaccc
     6361 atatgcaaac tgccggtgac gttcggcggc gggatcatga tgcagaaact ttcctggctt
     6421 tcatcgccat taggcttaaa gtagccctgc ttttcccagt gctcgtaaag cggctgttcg
     6481 atatcttgtg ggttatatgt cttttccatt atttccaggt tgccgtattc aggttgaaac
     6541 cagccacgcg gtaggcttta tagcgttcgc gcgccagttg tttcagagaa tcttcataag
     6601 gaacgaagtc taccacttct gtgaaagcgg tggcaaaatc tgcaaagctt gttcgcagac
     6661 taatcaatat atcgcgcggg ctgctgctgc gtttttgcgg ccaggcgatc tccaccggcg
     6721 caccgccgcg cggtccttct cccgctaaat tatgcggaac aaagctttct gccggacgcg
     6781 cccacagggc ttcatccagc cggtaagcct gcttttcatc ttcacaggcg atgagcacgc
     6841 gcttaccact gcgccaacgt tctgcggcaa tttcacacac cagctgctca acggcgctta
     6901 agccatcgac ggtggtgtca ttgtccagaa ggtagaacgt cgcgtttttc ataaatgggg
     6961 cttcttgtgg tggatttaaa tattgctgca ttcctcaccc taaaagatga gcaatgaatt
     7021 tctattgcgc tcgatcggtt ccctctccct tagggagagg gttagggtga gggtaaaacg
     7081 caaacttact cttcgccgtt aaacccggcg cggtttaaca ggaactgtgc cagcaacgct
     7141 accggacgac cggttgcgcc tttcgcttta ccagaacgcc aggcggtacc ggcgatatcc
     7201 aggtgcgccc agttgtactt acgggtaaag cgtgacagga agcaacctgc ggtaatcgcc
     7261 ccaccaggac gaccgccaat gttcgccata tcggcaaaat tggactccag ttgttcctga
     7321 tactcgtcac ccagcggtaa gcgccatgcg cggtcaccgg attgttcaga cgcggcaatc
     7381 agttcatggg ccagcggatt gtggttcgcc atcagaccag taatgtgatg acccagcgcg
     7441 atcacgcagg caccggtcag cgtcgccacg tcaatcaccg cttccggctc aaaacgctca
     7501 acgtaagtta acacgtcgca cagtaccagg cggccttcag cgtcggtgtt cagcacttca
     7561 acggtttgac cggacatggt ggttaacaca tcgcccggac gataggcacg cccgccaggc
     7621 atgttttcgc agccagccag cacgccgata acgttaatcg gcagttgtag ctccgcgacc
     7681 atccgcatca cgccgtaaac cgctgccgca ccgcacatat cgtacttcat ctcatccatg
     7741 ccttctgaag gcttgatcga gataccgccg gagtcgaagg ttaaaccttt acccaccagc
     7801 acgattgggc gtgcatcttc cgacgcgttg cctttgtact caatcaccga catcagcgat
     7861 tcgttctgcg aaccctgacc gaccgccaga taggaatgca tccccagctc tttcatctgt
     7921 tgttcgccga taacgcgggt aatgacattc ttgctgtagc tgtcagccag ttggcgcgcc
     7981 tgagaggcga ggtaagcggc gttacagata ttcggcggca tattgccgag atcttttgct
     8041 gctttaatcc cggcggcaat cgccagaccg tgctggatcg cgcgctcacc gctggtcagt
     8101 tcacggcggg tcggcacgtt gaacaccatt ttacgcagcg gacgacgcgg ttcgctcttg
     8161 ttcgttttca gctgatcgaa actgtagagc gtctcttttg ccgtctcgac agcctgacgc
     8221 actttccagt agttgttacg gcctttaacg tgcagttcag tcagaaagca gaccgcttcc
     8281 attgagccag tatcattcag cgtattaatg gttttctgaa taacctgctt gtactgacgc
     8341 tcatccagct cacgttcttt gccgcaacca ataaggagaa ttcgctcgga aagtacattc
     8401 ggaacatggt gcagcaacaa tgtctgcccc ggttttcctt ccagttcgcc ccgacgtagc
     8461 agggcgctga tgtacccatc gctgatttta tcgagctgtt ctgcaatcgg agaaaggcga
     8521 cgtggttcga agacgcccac gacgatgcag gcactccgct gtttctccgg gctaccgctt
     8581 tttacactaa actccatgca ctacgctcct gaatcttaaa gacaacggcg gtggctacag
     8641 atagaattgc aagctttcgt aactcatgtc cgctgttgcg atgacttcgt gttaatctta
     8701 acgttattac ggcattggca cgtcagaaca aaatctgaga ggtgaatccg ttgagtataa
     8761 ttatcttagc gacgatttcg acgactcaag agaataaatg acgtttaagc catgaaacaa
     8821 gctaaaatcc tgcaaaagac gagtttttac gggcgtattt aaagtgataa tcataagata
     8881 tctggtgcgg gagacgctca aaagccagct ggcgatactc ttcatcttgc ttttgatctt
     8941 cttctgtcaa aagttagtga ggatcctcgg cgcagcggtt gacggcgata ttccggcgaa
     9001 tctggtgctc tcccttctcg ggttgggcgt gccggaaatg gcgcagctta tcctgccatt
     9061 aagcctgttc ctcgggctgc tgatgacgct gggcaaactg tataccgaaa gtgaaattac
     9121 ggtaatgcat gcctgcggcc tgagcaaagc ggttctggtg aaagcggcaa tgatccttgc
     9181 ggtattcacg gcaatcgtcg cggcggttaa cgtgatgtgg gcgggaccgt ggtcatcgcg
     9241 tcatcaggat gaagtgttag cagaagcgaa agcgaaccct ggcatggcgg cgctggcgca
     9301 agggcaattc cagcaagcga ctaatggcag ttcggtgctg ttcatcgaaa gcgttgacgg
     9361 cagcgatttc aaagatgtgt tcctcgcgca aattcgacca aaaggtaatg cacgtccttc
     9421 tgtggtggtg gccgattccg gacatttaac ccagctgcgc gacggctccc aggtcgtcac
     9481 tctcaaccag ggaacgcgct tcgaaggcac tgcactgtta cgtgatttcc gcattacgga
     9541 cttccaggat tatcaggcga tcattggtca ccaggcggtg gcgctcgacc cgaacgatac
     9601 cgaccagatg gacatgcgta cattgtggaa cactgacacc gatcgtgccc gcgcagaact
     9661 gaactggcgt atcacgttgg tattcaccgt gtttatgatg gcacttatgg tcgtaccgct
     9721 gagcgtggtt aacccacgtc agggacgcgt actgtcgatg ctgccagcca tgctgctgta
     9781 tctacttttc ttcctgatcc agacctccct gaaatcgaac ggcggtaaag gtaagctgga
     9841 cccgacgctg tggatgtgga ccgttaacct gatttatctg gctttggcga ttgttctcaa
     9901 cctttgggac accgtgccgg tccgccgcct gcgcgccagt ttttcgcgta aaggagcggt
     9961 gtgatgcaac cttttggcgt acttgaccgc tatatcggta aaactatttt caccaccatc
    10021 atgatgacgc tgttcatgct ggtgtcgctg tcgggcatta tcaaatttgt cgatcagctg
    10081 aaaaaagccg ggcaggggag ttacgacgcg ttaggcgcag gaatgtatac cttgctgagc
    10141 gtgccgaaag atgtgcaaat cttcttcccg atggcggctc tgcttggggc gttgcttggt
    10201 cttgggatgc tggcgcagcg cagcgaactg gtggtgatgc aggcttctgg ttttacccgt
    10261 atgcaggtgg cgctgtcggt gatgaaaacc gccattccgc tggtcttgct gacgatggcg
    10321 attggcgaat gggtcgcgcc gcagggcgaa cagatggcgc gtaactaccg tgcgcaggcg
    10381 atgtacggcg gctcgttgct ctctacccag caaggcttat gggcgaaaga tggcaacaac
    10441 ttcgtctaca ttgagcgggt taaaggtgac gaagagttag gtggcatcag catttatgcc
    10501 tttaacgaga atcgtcgtct gcaatccgta cgctatgccg ctaccgcgaa gtttgacccg
    10561 gaacataaag tctggcgtct gtcgcaggtt gatgaatctg atttgaccaa tccgaaacag
    10621 attaccggtt cgcagacggt gagcggcacc tggaaaacca acctcacgcc agacaaactg
    10681 ggcgtggtgg cgctggaccc ggatgcactc tcaatcagcg gtttgcacaa ctacgtgaag
    10741 tatctgaagt cgagtggtca ggatgccgga cgttatcagc tcaacatgtg gagcaaaatc
    10801 ttccagccgc tatccgtggc ggtgatgatg ctgatggcgc tgtcgttcat ctttggccca
    10861 ctgcgtagcg taccgatggg cgtgcgtgtg gtcaccggta tcagcttcgg ttttgtcttc
    10921 tacgtactgg accagatctt cggcccgctg acgttggttt acggcatccc gccgattatc
    10981 ggcgcactgt tgccaagcgc cagcttcttc ttaatcagcc tgtggctgtt aatgagaaaa
    11041 tcgtaaccaa gcaagggagc gaaagctccc tttcacattg ttgataaagt caaatacgag
    11101 ttcgatcggt cccctcgccc ctttggggag agggttaggg tgagggggac agatcgcgcc
    11161 tgacttacct tcttctcccc cccagcaaac tccccaacat cccgcgtaca atctgattcg
    11221 tcacctggcg agcggcgctt ttcgccattg tttgcaccac accatctttc ttcccgccgc
    11281 gtggtccggt agtgccaaac aaaatatcct tcaatccacc aagaataccg tcatccaccg
    11341 ccacctcttt ccctttcgtg gggggattct tttgctgctc ggtactggcc tgaacgcctt
    11401 tttgcagcat ctcataggcg gactcgcggt ccacgtcatc ctcgtacttg ccatacaccg
    11461 gggagtgatt aatcaagcca ttacgctcat cttccgtcac tggccccatt cgcgaacaag
    11521 gcgcgatcac catcgctcgt tccaccactg aaggacttcc ttttgcatcg agaaacgaga
    11581 ttaacgcctc gccggtcccc agttcctgga ttgccttttc ggtatcaaat gccggattgg
    11641 cccgcatggt ttgcgccgca gcttttaccg ctttctgatc tttgggcgta aaagcccgca
    11701 aagcgtgctg aacgcgatta ccgagctggc cgagcacatt atccggaata tcagacgggt
    11761 tttgcgaaac gaaccagacg cccacgcctt ttgagcgaat aagccttatc acctgctcaa
    11821 tcttatccag cagtacctgc ggggcatcgt taaacagcag atgtgcttcg tcgaagaaaa
    11881 acaccagttt tggtttctcc agatcgcccg cttccggcaa ttgttcatac aactctgaaa
    11941 gcatccacag caggctggcg gcgtacagtt tcggcatctg ataaagcttc tcggcgctga
    12001 ggatattgat aacgccttta ccgttggtat cggtgcgcat ccagtctttg atatccagca
    12061 tcggctcacc aaagaagtgt gctgcgcctt gctgttccag cgacaatagc ccgcgctgga
    12121 tggcaccaac cgatgcgcta ctgatatttc cgtactgatt ctggaaggat ttggcgttat
    12181 cgccgatgta ctgggtaatc gcccgcaaat ctttaaagtc gagcagtaac agcccctgat
    12241 catcagcaat gcggaagatg atattcagca cgccagattg cacatcgttg agattcaaca
    12301 gccgcgccag caacagcggc cccagatccg aaaccgtcgc ccgtaccgaa tggcctttct
    12361 cgccaaagat atcccacacc accaccggat tggcatgcgg ttgccagtca ttgacgccga
    12421 tatttttaag ccttgtgagc agtttttccg acgccgttcc tgcctgcgcg ataccggtca
    12481 gatcgccttt cacatcagcc ataaacaccg gcacgccgat ttccgacaat gactctgcca
    12541 gtttttgcag cgtaacggtt ttacccgtcc ccgttgcgcc agtaatcagc ccgtgacggt
    12601 tagccattcc cggcagtaaa aacagttctg tgtctggcgt gcgggcaatt aacaggggtt
    12661 cgctcatgag atttcctcca gtttcctgcc tggagtatag gcaacggctg cgcactcttc
    12721 accgctaaat tcagcagatt gcgagatgcc ttccaaagag attttagtgc cgggcgacag
    12781 gcacccggca aagggatcag aagtcggctt tcagaaccac gcggtaacgc gccttaccgt
    12841 cgcgcacatg cttgatggcg tcgttaattt tcgacatcgg gaacaattcg gtggtcggtg
    12901 caaccttgct gcgggcggca aagcgcatca gcttacgcag ctcataaggc gtgccggtag
    12961 cagaaccaga gatgctgcgg tcgcccgcaa ttaacgtaaa ggccggaaca gacagcggcg
    13021 tgagaaccgc accgaccgta tggaaattac cgccataggt cagcgcctca aaataaggct
    13081 gccagtcgag gctgacgttg acggtgttga taatgagatc aaactgcccc gccagtgctt
    13141 tgagtgcctg cggatcgcgg ctattcacca ctttatcggc acccatcgcc agtacttcct
    13201 gctctttcgc cggattcgaa ctaaaggctg tcacctcgca tcccattgcg tgcagaagtt
    13261 ttatagcgat atgccccagc ccgccaatac caattacccc aacgcggctg gtggctgtga
    13321 tatggtgcat caacagtggt ttaaagaccg tgataccacc acacagcagc ggcccggcgg
    13381 actcgatatc aatattttct ggcagtggaa tcacccattg ccagtctgca cgcaacttct
    13441 cggcaaaacc gccgcgattc ataatcgtcg gcaccgcgcc ttgctcgcag ttgatctgat
    13501 taccgctaat acaggcgtcg cagtgaccac agctacgcgc cgtccagcca attccgacac
    13561 gctgaccgac ctgcaaacct ttatcctgcg cggcgctccc gagcgccacc acgcgcccaa
    13621 ttacctcatg cccggcaacc agcggatatt gtgaaaatcc ccattcgtta tcgatcattg
    13681 acagatcgga atgacagatc ccgcagtaat ccacctgcac ttcaacatct tgtggcttca
    13741 gctcaccggg atcgtactca taaacttcca gttcgccgcc cgcttctttt gcggcatagc
    13801 tttttatcat cgacattttt tggtccttct ctggtgttgt ctgggaagtg tagagcatgg
    13861 cagggcgggg tgcctggagt gtgacaaagg ttacacatcg ctgtatgcaa tgctgaaaat
    13921 ttcagcactt agcgaggtgc gagcaagctg gcgcttgcat ggtggcgtgc gacaggtata
    13981 atccacaacg ttttccgcat acctcttcag tgccgaagtg gcgaaatcgg tagacgcagt
    14041 tgattcaaaa tcaaccgtag aaatacgtgc cggttcgagt ccggccttcg gcaccatcgg
    14101 aacatcaata gacgtcaacg gacgtctttt tttgtgcctg aaatccagta tttacccatc
    14161 attcccgcta tattaactct ctcaaggtca accgacttca acgtgcatct accaacagat
    14221 gttggtacag atgatggtat ttccggttcg ataatgcttg taccaacagg gaggggataa
    14281 gcatggctct aacagatatc aaagtcagaa cagccaagcc aacggataag caatataagc
    14341 tgaccgatgg caacggtatg caccttcttg ttcatccaaa tggctctaag tactggcgtc
    14401 tgcagtaccg atttggcgga aagcaaaaga tgctggctct gggtgtttac cctgacgtat
    14461 ctcttgcaga tgccagagct cgtcgcgatg acgctcgtaa gcttttagca aacggcatcg
    14521 atccgggaga taaaaagaaa aatgataaga ttgagcagga ggaagcacgt acttttgagc
    14581 agcttgctat tgagtggcat gccacaaata aaaagtggtc ggaagaacat agtcgacgag
    14641 tgcttaaaag cctggaggac aatctcttcc ctgccatagg taagcggaat atcgctgatc
    14701 ttaaaactag agacctgctg gccccaatca aagcggtaga actgtcagga cggcttgagg
    14761 ttgcttcacg attacaacag cgaaccacgg caattatgcg ctatgccgta cagagtggtt
    14821 tactggacta taaccccgcg caggagatgg ttggcgctgt tgcttcaaat aacaggcagc
    14881 atcgacctgc tcttcagttg aagctaatcc cagaactatt acggcgcata gatagttata
    14941 ccggtagacc tcttactaga cttgccgtcg aactcacgct cctggtattc attcgttcaa
    15001 gtgaactacg ctttgctcgt tggtctgaga tcgatttcga aacatcaatg tggacaatac
    15061 ctgcagagcg cgaagctatt gaaggagtaa agcattcaca gcgtggttca aaaatgcgta
    15121 cgcctcatct ggtgccgctt tctcatcaag ctttagcaat tcttaaagat gtttacaaac
    15181 ttagtggtga tcgcgatttt gttttcatcg gcgatcatga ccatcgcaaa ccgatgagtg
    15241 aaaacacggt gaacaaggcg ctgcgcgtta tgggttatga cacgaaggta gaggtttgtg
    15301 ggcacggttt caggacaatg gcctgtagtt cattgatcga gtctggattg tggtcgaggg
    15361 atgcagtgga aaggcagatg agccatatgg aacgtagctc agtacgcgca gcttacattc
    15421 ataaggccga acatcttgat gaacggcgac tgatgctgca gtggtgggct gattttttgg
    15481 atgcgaatag ggaaagcgaa gttagccctt atgactttgg caagtagtct aattcctgat
    15541 gcttgctatg ttcgaatttg aaaagccggc ttgaactata acccatactt ttttataact
    15601 gtattattct ggcgactcag aggtgcacta tgaaaacttt cgatactcaa cttgcgatga
    15661 gcattgtatc gcactcaacg ggaggtttta gttatgacac actcgctagg gcattgattt
    15721 ctaaagataa aaacgaaaat tctgacgtcc ttcttgagtc atgtcgaaat ttttgtctct
    15781 ctcttgagga aaaaggtatt ctgaggcgat gccaaagatg ttctcattct caagatgagt
    15841 atttcgagta tattcctcac taacatcagt ccctgaaaat tttttcaggg actgattact
    15901 ccgttcttgt catccccttt tttctcctgt agcttgtgta acacgattct ggggggcgat
    15961 tgtgagcaac atcaacttaa taaccacatg tacaaacggc aaacactacg gtagtaggga
    16021 tatattgagc ctgagtcaat tttcatcagg ccgaacccct tcaaatgtgc tcgtgaattc
    16081 ttggtgcaat gctctgaatg aagctatttc tacatctgca actgtatgtg cagaggatct
    16141 ttataaaggt gggcactggg cgacggctaa agccatctta gatgattatc ctattgattt
    16201 atggattctt tctgctggtt taggacttct tcaccacaaa gacaatgttg taccttacaa
    16261 agcgaccttt gctgttggat atgacgaatc aataccattg tattctcaag aatatgtagg
    16321 gaaaagtttt catagaacat ggtggaaaga aataaccaat agatctattt ttaaatctaa
    16381 gcatcctaca tctattgtag aattaatgaa aaaaagaaaa agagactatt atattatatg
    16441 tggctctcca gattatatta atgcaattga actagatatc attaatggtc ttgagtatct
    16501 agttgatgca aaaaaacaac tgcttatcat aacttccaaa aaaatcaatg gtaggttaac
    16561 tacatacctt ttcaaaacca accaaaatat ggctcagtgg ctgagatgca atatgctcat
    16621 gcttaatatc agtgtggcaa aatacattgt gaaggaattt acgtcaaaac aactcaatga
    16681 tttaaatgag ttatctcaaa agttaaaaga agaactcaag gagttacctg agcgtgaagt
    16741 gaaaaaagga attcgtcgta gtccggagga agttaagtct ttcattttaa agattatgga
    16801 aaaaaatcct ggtatcagtg caacacacgc gttgcgtgaa tttcgtgact cggggaattc
    16861 atttgaggaa aaacgttttc gggctgagtt tatggccctg agagaggcta aaccttaatg
    16921 ctacttgcct gggtttcatg gtagaatccc ccgttttttg aggctttgca gtggcgtcac
    16981 aggagagtaa gttgtcgaag ctaaagtatt ttttccctga tagtcaggat tttatcgatc
    17041 ccagtttcga cttctttcgc gaaacgcgta acgaacatcg cgtgcgtcaa cgtgacgatc
    17101 agtatccgca tgaggttttt cctcatcctt acgatggtat gctggtttct aaagctgtag
    17161 ttgatggtct tggcggcggc gagagcaaat atactcgtgc ccagcgtttg cgttacttcc
    17221 gtaatggaat gaagcacttt ttccgtctgc cggaaaatat ggaaactatg ggtgattgcg
    17281 gagccttcac ctatgttaat caggacgtcc cgccataccg tgtggaagag gtgattgagt
    17341 tttacgaaac ttcccgcttt aaccatggcg tttctctcga tcatatcgtt tttggctatg
    17401 aaaaacctgg tgaggtattt agtggcgaag tattgactga gtgtcgccga cgccaggata
    17461 tcacgctgac cttggctcaa gagtttttaa ataagtctca aaagtcctgt ttcaccccct
    17521 ttggcgttgc acatggatgg agcaaaacct cctatcgtca gtctgtagag gccctgctgg
    17581 ccatgggata caaaaatatc actatggggg ggatggtgcc gttgaaaacg gcgcagatcc
    17641 tagagactct cgaagagatt aagccgttgc tgaaaagtga tacgcgtgtt cacttgcttg
    17701 gtattgcccg tccagagagt ttctccgact ttatcaagtt tggtgtgacc agtattgact
    17761 cgactacacc gcttcagcag gccttcaaag atcgaaaaaa caactatcat acgcttgatg
    17821 gcccagccta taccgctgtg cgtgtccctc agtttgatgc gaatccaagt ttgagtcgca
    17881 aaattaaatc tggcgtgatt gatcaggata ttgcacggca tctggaaaag gatgccatga
    17941 atgccctgtt cgaatacgat aaaggggctt tgtcccttga gaaggctctt gatgcagtcc
    18001 tggcttatga acgtctgcat tcgggtgaaa aagaggccga caaaattcgt gcggattatg
    18061 aacgtacgct aggagaacga ccctggaaac aatgccagtg caatatttgc caggccatcg
    18121 gtatcaatgt catcattttc cgcggagcag aacgtaaccg tcgccgcggt ttccataata
    18181 ttcaggtgtt gtacaaccgt ttacagcaca cattgtcatt acgctcagag gaactgtcat
    18241 gagtgaatat cgtgttcctg ccctgcgaat ccgacagggt gaggagaggc aactctatag
    18301 ccttgcgata gaaggtaaac agatcagcaa aattgcagcg atttcgcgta ttcgtcgcgg
    18361 cgaagagagt ttggttggtt atcagcgtcc agaagtacgt aaccatattc gcgaaattca
    18421 gcgctacatt gagagcgcaa atccgatgat accaaacccg gtgattatcg cttttgataa
    18481 gcgtgtgcgt tttgaaccgc ttacagataa tgacgacatg ggacatctgg taataccttt
    18541 ctccgaagat aaggattttg agaagccagg ttttattgtg gatggtcaac aacgtactgc
    18601 tgctttgcgg gatgcagaaa tcaattcgtt tatgatgccg gtctccgctt ttatcgctaa
    18661 tgacgcggaa gaacagcgtg aacagttcat gctggttaac tccacaaaac cgttgcccaa
    18721 aacgttgtta tacgaactgg caccgcatac ccacggtcgt ttgccatccg atctgcaaat
    18781 gcgtaagttt ccttcactgc tgactcaacg actgaacttc ggcgaaggtt cacttgcagg
    18841 gcgtatcaaa acggcgacca atcctgatgg tgttattgct gacaactcga tgatcaaaat
    18901 gatcgatgcc agtcttcgcg agggagcatt gtatcgcttc cgtgacccgg cgacagggtt
    18961 gggggatgaa gagaagatgg tgaaactgct gaataacttc tggtcggctg tggaaactgt
    19021 gtttactgat gactgggata aaaagcctcg ctattcccgc ttgttacatg gcgttggtat
    19081 tcttgcactt ggcagcttga tggatgaaat cgatcaggtc catcaggact ataaaggtga
    19141 acctggctgg actgagatcc cttcctacac tcgttttgtc gaagagctaa accgaataaa
    19201 gccgctttgt gcatggagca gtggcgtatg gaacttcggc acagatattg atggtcagcc
    19261 tatcgtccgt aaatggaacg aactgcaaaa tctttcaaaa gatatatctt tggttactga
    19321 ctatttggta actggctata tgaaaactgt caatgcagat attaaataag ggtgacaacc
    19381 caattggcat tagaagtatc gagtgctgat tatcgacgtg gggggctgca gatatggtgc
    19441 agaagttcaa attctgtgca agcgccagac agcccccatg ctttcattct tatcatcaaa
    19501 cgctgacctt gttacgatat atgttcgtaa ctcatgaaaa atcaagagtt ttttgttgaa
    19561 attcagtcgt ttcacgagtt ttgaaagccg gtaaataagt cataggccgc accggattac
    19621 ccaccaatcc cccctaaaag tcatagtaga ctagtaaccg tgatccccct ccttgacaat
    19681 catctttacg ggttgcagtg tatgacattg tccttgtatt cagtgatatt atacgtataa
    19741 aaaatcacca ttaatcaaag gcttttaaaa tcactgttac gcacagcaaa tttatggatg
    19801 gatatatgcc ccttgaagtt ggcgacctcg ttgactcgcc ttatggaatc ggcaaactta
    19861 ttcgcattaa caataatgat gctctaatta agtatttcga ttctcccgta aattatgaag
    19921 gcatagagca aactgtcgaa gtaaaacacc taaaaaaagc cgaactccac gcggaaagtc
    19981 tggtttatcg ctacgactac gaggttgcac actggcagat tgcacgtgtt gttggtgccg
    20041 tgcctggagg ggtacgtttg cattttccta acaagcagca ggaagacgtc agcttaaatg
    20101 atatctttgt gcgctgggat cgccctatca gcgatgctgc ggcccttctg gccgagcgca
    20161 tcacctatac ccccttctgg caagatgccc gtctagctta tcagcatcag atgctgaaac
    20221 aacgcaacgc ttgtgctggg attacctctt cgctgtcgtc cagtattgaa ctcgaacctt
    20281 accagttggc cgtcgcgcgt cgggtgttat ctgaccctat tcaacgctat ctgttggctg
    20341 atgaagtcgg cctcgggaaa accatcgaag ctgggctgat cgtgcgtcaa cacgtcacgg
    20401 aaaatccgct cgcccactgc gtggtgattg tggcgcctgg agttctgcac cggcagtggc
    20461 agcaggaact ttctgcacgt tttcacctgg aggaactgct taataagtcg atccatatca
    20521 ttgatatggc cgccttcagc acagcggacc ccctgtcgtt ccgccccgat atgctggtga
    20581 ttgacgaagc tcatcaggtc ggtgcctggg catgggatgc agagtacgag cagcgctacg
    20641 ctagtgtgaa ctacttggcg caacaaagtg aaaaattgct attactatca gcgacacccg
    20701 taactggcaa tgaaaagaac ttcctggcca tgctgcatct gctggatgct aaaaattacc
    20761 cactgactga cactggctta cagaaatttc agcagcgtat ccagcagcgc gaagaaatag
    20821 gttcactgtt ctacgcgttt aactgtgata acgacaacat gacgctggaa gagaacctgg
    20881 aagcgttgac taggatgttt cctgaggatg aagtactaaa cgggatggct tcacagttgc
    20941 ttccccattt agatatgatg caaccgctgc ggagtgaggc gcgtgatctg ctgatcaata
    21001 aaatccgcca ctacattggt aaccgttacc gtctgcacca ccgcctgcta cgcaaccgcc
    21061 gtagcaaccc cgccattagt gtcctgatgc ctggcttgtc cggcctatca ctaaaaaaat
    21121 atgccacgac gaacgccagc aacgacatga tgatcgcctg gcgcgaatcg gcaataatga
    21181 tgcacccaca agaccccacg ttggcggcaa tttatcagtt actgtttgaa gccgctatcg
    21241 ctacgccgga actactggcc cggcttgcaa actatcgctt acagcaggag tcacttggtg
    21301 ccgcgcaggg ctttctctat agtgattcac agctcgcgct gttgcagcat ccgctgtttg
    21361 atggcgagaa ggagatcctg cttgagctga tagaccgctg caaaatggag tgtgacagca
    21421 agcgccagcg cttaattgat gtattggaaa aacttctgga tagtaacgtc agagaactcc
    21481 cttatattgt ggtgttctgt gaccagccat gggtagccga ccaggtattt accgacctga
    21541 tgataccatt tattggcaaa atccagcggc ataaccccga caaagaagtg cgctttggca
    21601 agggaagcaa atgccagatc ttagtgtgcg atcgccgggc tgaagaaggt gtcaatctgc
    21661 acggcgggcg caagattgcg ctgcattacg acttgttgct gtcgcctaac cgtatggaac
    21721 agcgtcttgg ccgcttgaat cgctattgcg cgactgagag tgcgactact atcctcagca
    21781 tggcgctggt gagtgaagca gagggtctgc aaaatcagtg gctgactatt ctcaatgaag
    21841 tgttcgatgt cttcgaagag tcgattgcaa gcctacaata cttgattgat gaggaattac
    21901 agcggcttat ttccaatctt tacccgctgg gtgaagagag catgatgcaa ctcagtgcgc
    21961 gtctggctgg tgaggatggc cgccttacgg tggaaaagca gcgcatcgaa atgcaggaag
    22021 tcctgctgca aattgatggc gatatcatcg aagccagaga gtatgccgat gcactggcgg
    22081 aaatagatga gaatgaagag gaattccgcc gctgcgctcg taatctgata ggtaatgtac
    22141 tgaaattcga ttttattcca gatgagaaag atccatcgat attccgctat cgcttcaacc
    22201 ctggtgatag agggacgggc accttagtca gcccacagcg cctacaaaaa cactgcctgc
    22261 tgggctttga tctcaaccaa tctagcggaa gttcgcccat gacttggcca cttagctact
    22321 accgggctga tacctctcag ggtaaaatcc gcccggctcg cttgggtgaa cctttccatg
    22381 atgccatcct acaaatgctg gattttgaag aacgcggtgt tgctagcgcg attatccgta
    22441 tcacaccagg catgggcgat gaaaatattt ttttccgcta cgattttctg attgaagctg
    22501 atgtccatac accagcactg caacgactgg cggaccatct gatgcctcct gaaaccatta
    22561 ccttgtggct ggaccaggcc ggccagcagg tcaccaacgc agaggtgttg atgatactta
    22621 atgaagacta taaaccgaag gataagggcg gacgccacct aaatctcaat gaggaacgct
    22681 gggcgcagat ctcccattgc atcagcgcta aagattggcg cacctggtgt aacgatagct
    22741 atagcatagc ccagcgcctg gcggtggaac agttcgccac acaacaggct ctcagcctga
    22801 gccgactgga acattatcta agcagcgccg cgctgcatca tgctaaccgg caggagacag
    22861 ggcagatgct gcgccagggt attgcacagc cgaaaatgac ctgcctggcg acgcgtgcct
    22921 taatcattgc atcagaagct atattggatg aggactcata aaccggatga atttggcgca
    22981 actgattgat aatgatttta tttcatcaag gttgagtgag tgcctgctgc cagaggcgac
    23041 tgccggacac ctcgaccgcc gggcgttgat ccgtgactgg ctgtaccggg aaaaacatgc
    23101 ccaccacaac gataacgagc tgaccgtccc tgatgatagc caacctggtt ggccaagaca
    23161 ggaggagtgg gaagccagcg gtattaactg tcaacgacta ggtcagacct ttctgctcag
    23221 cgctggccct gcttggtgtc cgcagtggct ggagcaggga aacggcatgc cttttctcgc
    23281 cagcgatcag caccaattct gccgccagga cactcgagta ccgatggact atgtcctgcg
    23341 ccgttacttc aagaaggaca actatatcag ctatcaggca ccgggccagc gcgatgcggt
    23401 acgccgggct ctgttcgccc caccgggcag tacgctgttg gtcaatttgc ccacaggcac
    23461 cgggaaaaca ctggtagcgc aagcattagc tctgacagcc tcagctcccg gggcactttg
    23521 tgtactgatc gccccgacca cggcgctggt gttggagctg gctagccgtt tccggaagtt
    23581 actgattgaa gcagggaaca aagcagaatc tgtcaccggc tggtatagcg gcttaccggc
    23641 gcaggataaa tatgatacgt acatgcgtat ccgtgtgggt gagcagcggc tgatcgtcac
    23701 ctctcctgaa gcgacctgca gttccctgca gttcgcctta tttgaagcag caaaacaggg
    23761 agggctgcgc catgttattg ttgatgaagc gcatattgtc gccagctggg ggaacgactt
    23821 tcgcccgcat ttccagcaac ttggtggctt aattcgtggg ctgaagcgcg tcagccgtga
    23881 agcgaatctt acaccgtgct caacactgct gatgagtgcg actatcaccg aagccagccg
    23941 taaaatcctg cgcgatacct tcgatcagga gatgagcgaa ctccatgcct gccatctgcg
    24001 cccggaacct gcttactggt gttatcgggc aaaagaccac agcgacaaac gggataaggt
    24061 gctgcaatcg ctggctcatg cgccacgccc gctgatcctc tacgtgacgc gaccgaaaga
    24121 agctgaagag tgggcgcaac agttgcgttt gcaggggtat cagcgtttgg caacatttac
    24181 cggtgataca ccgagtgaag tacgccgaag cctgctggaa aaatgggata aaaaccagct
    24241 ggatatcatg attgcgacct cagcatttgg cgtaggtatg gataaaaacg acgtgcgcac
    24301 agtgatccat gccacagtgc cggaaaacat ggaccgcttc taccaggaag tgggacgtgg
    24361 tggacgcgat ggctatgcct gcacctcact gctaatttac aatcatcagg atgtcaaaca
    24421 ggcagaacat ctgtcctcac aaaagttgat tggtcttgag ttgggcctgg aacgctggaa
    24481 aaagttatgg ggcagtgccg aatcggtggg cgacaacctg tatcgtattg atatagagag
    24541 gatccatagc ggccttaatt tccgcagcaa acaaaataaa ttatggaact tgcgtaccgt
    24601 actgatgatg gtgcgtgcag gagtgctgga actggatgcc gatctacaaa acccgccaga
    24661 caaaaaagac tttgccgatg ttaatcgcta cgaagcggca aaagagcaaa tcatccgaca
    24721 gaacggaaat tcactggtag tacgcatcct gcgtagtcac cacaccggag aagaattgtg
    24781 gaaaacacgt attatccctt cccgtgaaga gacgctgcaa gctgcaaggg ctaaccataa
    24841 tgcattaatc aactggctgc atacgccact gagcagaccg ctgtgtgagg cacttgtaga
    24901 tctctactcc atggcggaat ttattccggg tcacgcctgt ggtggttgcc ctgcctgtcg
    24961 cgataatcag gcgcttacta gtaattatcc gagcccaccg acgctgttgc ttaacccgcc
    25021 agcgtcggtg gcacagcagg cgttaagccg ctggcaggcg ctcagcggcc tatcttactc
    25081 cagttgcttt atcacctatc cgccagttaa cgacgatgag tgggaacgtg agaactggta
    25141 tcaccgcatc gcgacgctac tggtgcaact gtatcataga ggcattgtcc agcgcgtctg
    25201 ggcagatcct gccttgttgc atagtatatt tagcgccatt ccgcgcggtg agcgcctgat
    25261 cttgttgagt gacgaattgc ctgcacgtga tgagccagcg ccggataacg atgtaatggc
    25321 cgagttggca gagttggtac ttcccactca agagtcctgc gccaatggtt acctgccgcc
    25381 tttcaaccca gcaccattac aactgacgct gatcccgcat gatatgcccg atcctcacca
    25441 tcctggcggg gcgcattacg ttcttctcga taatcacaat tggatcacca tcgaacaact
    25501 tcaaaggaaa ctagacagtg tcgattatca ataatgccca tggtggcagc cagtatgccg
    25561 tgctggccgc attttatcag gtgctgaaag ccagcccgaa gaaccaacta ccgcgtgaaa
    25621 agctgatggc gctctgtgca ccggaaacat tgcaaaccgg cgactcacaa aatgcacgtg
    25681 gtaaagcgtc tcaggaatta agagcatggc tggacttggg gttactgacg gaagaaaaag
    25741 tagaagagac aacacaaatc agtttcaacg cgaactattt cagcacaaaa agtatgccgc
    25801 tgcgccaggc tgcgcgccgc tgtttacagg cacaggaaaa taacagtgac ctgagctcac
    25861 gcgatgaacg cgccgtcgac cttacccttt tggctgcatt gctgctggcg ctggatgtct
    25921 atcagaacgc agaaatcaaa tcgggcaacc ttgaagtgct ggtgaacacg tttatacctg
    25981 attttcgtat caacagtaat gaaattgctg tcgttccggg gtatctcagt tggctgggct
    26041 ttgctcaaca actcactcgc gacagttacg ccattgaccc caccgattct attcgtgaag
    26101 agttaccgtt ccttatgcgt gttggcgaac aactttccat cggcgaagtg ctgcaacgtc
    26161 ttaatcgggc gctcccggtg ctagatggtg gcagttatcg ccagcaggtc gaggagcgta
    26221 tcagtctgta tggctggcac tctcttagcc ctaaccgcct ttccacctcg ctgtcgcgtg
    26281 cgctgctgcg gcttcagctt tccggagtaa tcaacatgaa ggctgagtct gacgccagcg
    26341 gcgcaatgca gttaaccggc cggaacggca gcgtgctgcg taccgtaacc catctgacct
    26401 tgaatgatgt gggagtccac taatgccaca actacagagc tactggccca gcgagcagaa
    26461 cgttactgcc tgcatcctaa ccgaggctga gtcactggct gacagccagt tgctggcggt
    26521 gcatgaaccg atgcgtctcg accgcattga gtttcaaagt ggtaaggtca cgcaggtggg
    26581 agagggggcg ctgctggact ttctgcttga acataaccgc ccgctgccgc taattggcgc
    26641 ttctggcgtg gggaaatccc acttggtacg ctgggttcat gctcagctca aacgtcgtga
    26701 agatcatgcg aaataccaca ttatccgcat ccccaaaaat gcttctctgc cacgtgtact
    26761 tgccgccatt ctggaaggtc ttgacggcga ggagtatcag agtattcgtg aaaaggttaa
    26821 cggagttgga aagcaattaa tccccgaaaa cgttgccgaa catattgctc ttaaattgcg
    26881 tcaagcgcta aacgcagcat atacagatgc cattgaagag cttcgccaag aaaaaatggg
    26941 aaaaattcag ctggaagaaa gcagaaaaaa gcagctggaa gaaattcaac aacacgcagc
    27001 atcatcccga ctgcccgcgc tgttttttga cagcgtgatg acgcagtatt tcactgctcc
    27061 tggcgcctgt cttcacaata tagcgcagcg cttctgccag ggagctaacg acgacagtat
    27121 tgccaacttg cggtatgaaa tgtctgcgga agacttcacc ttcaaaggac tggacttcag
    27181 gcaggtttca ccaacagtgc ttccctacct gcgcaaccaa cagttgctta ccagtgatga
    27241 aaaaaagcaa gcagcggctc gcgttgtcaa cgtggtgcgc agccaggcgt tagaagacac
    27301 cttcgtcgaa ctatttagct ttaaccgggc caatttccag gatctgatgc gtatgatccg
    27361 ccgacagttg ctggcagaag gtcgcgacct gatccttctt gtggaagatc ttaccgccac
    27421 ctcggcgatt gaagatgtcc tgatcgcctg tctgatagag gaagatgagt acgacggcaa
    27481 aaaggtttta tgtactctaa gatcgattat tgcggttact gagggtcacg atagctttaa
    27541 gcgcctacgt aatacactag gcacccgcgc ccgctacgaa tgggtgatcc agcagcatgc
    27601 cagcgaaaac gatgtcgcgc tgaaaaaacg cgttattgac ttttgcggcc gctatctcaa
    27661 cgctgcccgt cacggcgctg ctgctctgga aacttatcac ctccagcaag acgcgcagtg
    27721 ttatcaggag attcctgtat ggcaggatca ggaggtgctg gagaacgaat ctgctgcgcc
    27781 agcgctggcc agttttggca gcagtagcat tggtcatccg ctgtttccct tcaacccagc
    27841 agccattggg cagttggtag aacgacactg caaagttaaa gaacaaggcc tagtgtttat
    27901 cccgcgtaat attttgcatg aaattttgcg cgagccactg aaaaagtatc gccagaatta
    27961 tctggacggg cagttcccgc catcacaatt tgctgagatt gtatgtaacc cggcattaca
    28021 gcagagggta cgcctggaag gcctcagcca gcctgagcgg attaattcac tgctggctgt
    28081 ttgggggggg aatagtacaa acctggcagg tcttacgccc gccatctgta aagagtttgg
    28141 tctgccggat gcggcagtac tgttgggggg cggtggaacg ccaccggaac cagcaccgga
    28201 accagtaccg gaacctgcac cagtaccgga atcagtaccg gcaccaccat caccacttga
    28261 tgaatggaaa ctcgtgctgg ataaatggca ccagagcaag acgctcgagc aaaccagagc
    28321 ccgcgacatt cgtaagtggc tcctggaagc gctgaatgcc cgtatcgact ggtcaactga
    28381 gcttatccag acctctctca tggccagctc agcaaaaact cagggtagga tccacttgcc
    28441 cggcgtgctt gtagggaatc agtcacatcc gctggtgaag cttgaagata ctcctgagtt
    28501 gcgtagcgcc tgtctggcga tggcgcactt caaccattat cagagttggg attatgacgg
    28561 cagtgagatc gactacgccg cctttcatag tttcatggat tgcattgagc acgaagtaaa
    28621 actcaaggtg ttgcaggaag aacgcgagga gctttctagt atcatcaacg atctgcagtt
    28681 aagtggtgca ttccttgggt tggatggatt atcagcatcc cacccggcca cgctggtgca
    28741 ggcactgtta acggaaccgc aagtcgcaaa cagcaaccat ccactgctgg atgagttctt
    28801 aacccaagcg cgcgacaccg tgattgatga gcatctgaaa cgtcgcgagc gtttaatcgc
    28861 gcttacggcg gcgaaaaaac cgggtgctca gccgtatgct attaacggct taatgctggt
    28921 ggaggcgtct aagaaacaat cgccagacgc tggcaaacaa ccgggcaaga tccatgaagt
    28981 caaaagtaag ctcggtggct accgcaccct gctattgaag acccaagaga gcatcactga
    29041 acgcctgagc gacggcaaca gcgccagcct ggcagcggtg aacctctgcg acaccatgaa
    29101 ggagatagtc gaactggcga atagcgcgga cgtcgcccgt ccaatgggtg aaactgtacc
    29161 ggtactgctg aagttgctga agagctggaa agatccagag ctgaaaaaac tgatcagaca
    29221 actggaaaaa ctgacgttgc cagccgataa ctcgcacatg ttgatgagag aaatccttgc
    29281 catcaatggc gagcagtttg aggcgtttcg acagttatta gagaattggg gcaagttcga
    29341 agatgccacc gacaagtatg tgcaacagcg tataagcgat aagggcggag accaagttga
    29401 ggatgcagaa aaccaagtta cagataccct ggcaaacctg gctgaacagt taacactgct
    29461 ggaggcggac ttatcatgag tgaagtaaac atcaatgacg tggtaactcc cgtagccagc
    29521 gtaccggaag aacgcggtat ttttgcacgg cgcagcggtg attttaaagc acgccttcaa
    29581 cgctaccaac aaatggagaa agctcaggat atccgcgata acctgctgcg gatagcaaaa
    29641 aaaatcgata ctccgaccca aacactagca caggccctct gtagctatag ggtgttaagg
    29701 caggtccacg acgatgaaac gggtaagccg attgttggtc cgtttgaccg tgcgactttc
    29761 ggcaatccac aaatcctgct gacggccttt tgccagcagt acgcgacgca taaacatgat
    29821 gttgagcaag agggtgaact tgccctgcta actcaagaaa ttaggcgctt agccagcgaa
    29881 ctcagcacgc acaccaccgc ggcgtgggtt aactatattc gcggattaaa agctcagtgg
    29941 gaagtggatc agagactgtt cagtaacttg gcgcatcagg aaggacaacg aaaagtacaa
    30001 cagcactaca ttgatctcgt ggaaaagttc accagcagta gccgggggct gccgaaaacc
    30061 attgaagaat ttgagacggt gagagacctg catgagaaac tctgccagca acgcggagca
    30121 cttaagctgg atgtgccaga agaggtcaat cacttcctca aagccgtagc cgggcaaggt
    30181 gccacgctcg atatgttgac acctaatgta ctcagttggc tgactgaaga agacgacccg
    30241 acgcgctatc gtataagacg cctgtaagga gccgtagttt caatggaaca gattattcgc
    30301 gcagtacttg atgggctgga gtcgcaggag gcggtactgc tcacttgggg taacacacaa
    30361 ggttttttca ctgagaccga gctccgtaat actatttctc aggtcctaca gaaccacccg
    30421 ctcgacgcca acggcctaac tagttttggc atagtgaaag ttatgatcga tcgcggattg
    30481 ctgctgcgcc accagcaaaa tggtgtttcg gtgtttcgta cccgcatggc ggagtccgtg
    30541 cggctttaca gccagttgcg ccagatgttt cctaagcacg gctttaatga taactggcgt
    30601 actgcaccga cgttggtgtc cgactatcgc ttcttacgcc gccagcgcaa atacccgaag
    30661 cgtgaccggc aggctgctga agttttgcag caacttgatg aaatagcagg ttttacctct
    30721 acgcaccgcc aactactatc agccctgctc agccactcga gcggaatgta caacctcgcc
    30781 tactttcaac aagaagcctg caaaaacgta ctgcgcggat tgcagcagag ccagcaccgc
    30841 tcgactgcta ccattgtctg cgccggaact gggactggta aaactttggc gttctatctg
    30901 cccgctctga cctttatcgg cagtgaattg gtcgccaaaa gaaaagacgc ggtgaaggct
    30961 ctggctatct acccgcgcaa cgaactgctg aaagatcagt ttattgaaac gttgcggcag
    31021 acgcgcaaat tgaacactga actggcaaag aaaggtgtgc gcaaagtgcg tatcgccgca
    31081 ttgtttggta tggtgccaac taataaagag gcgatccatc gcgactacat gaaagatgct
    31141 tggtgcaggc atcgcaatgg catggcttgt ctgtacattc cctgcccgac agagagttgt
    31201 cgcggtaaaa tggtctggca caccgccgat tatgataaaa accttgaacg cctgcattgc
    31261 gacagttgta gccagaccat cgagcctgac gaagtgatcc tgacgcgtaa gcgtatgaaa
    31321 atagaactgc ctgacattct attcactagc accgaaatgc tgaataaaca gatgggcaac
    31381 ccgtttctgg catcgctgtt tggcatcggc aaaaacgtgg tcccaccgtc gatgatgctg
    31441 cttgatgagg tgcataccta ttccggcgtc agcggtgcac agaacggcat gctgatccgc
    31501 cgctggcgac atctgtccgg tgccacaccg cactttgttg gactgtccgc aacgttggag
    31561 caggcgacgc gctttatggc ttcgttaacc ggcttggaag agtacctggt ggcggaagtt
    31621 agtccgatcg aagacgatat ggagacagag ggcgcggagt atatgctggc tctacgtggc
    31681 gacccggcgt cccgctctag ccttttgtcc accaccattc aggcctccat gctaaccagg
    31741 cgtatgctcg acaacgccgc agtgccggtc agcaacggta tgtacggcac gcgcagtttt
    31801 gtatttacag atgatattga cgtcattaac cgcctctatt tccagctact ggatgccgag
    31861 ggtcgttact cgaatggcaa tatcaatgcc aaaaaagaac cgctggcgat gctgcgcggc
    31921 gatgcgccaa atgaagagaa atttaccttt ggtcagcaat ggccgttggc taaaatgatt
    31981 ggccatacac tcgattctgc tgaccgcagc aacgttaagc gcacctcttc gcaggatgct
    32041 ggcgtcgacc atgctgcgga tctgattgtc gctaccgcgt cacttgaggt cggatttaac
    32101 gacccgaacg tcggtgccgt tatccagcat aaagccccgc gcgataatgc ccaattcctg
    32161 cagcgtaaag ggcgtgctgg acgtcaacga accatgcgcc cgtggaccgt ggttgtgctg
    32221 tccgactatg gccgtgatcg catggcattt cagtgctacg aaaacctgtt tgagccggta
    32281 ctaaaggcgc gccaactgcc ggtcggcaac agttacgtac tgcgtatgca ggcggccttt
    32341 gccactatgg actggctctc cagccgtaac gagtatctta atcagtggaa tcgtggtatc
    32401 tgggatgacc tatccgtccc gcaggacaaa ggtaagccat ctgaagctca gtcaaagctg
    32461 gccgatctga ttgaagacct tctgaacagc cagaaaatcc agcaggagtt taactcatgg
    32521 ttggctgaag cactggggat taaggacgaa aaactgctgc agtcattgct gtggcaaccc
    32581 ccacgcgcga ttatgaccgc gtttcttcct acggtactta gaagactgcg ttccaactgg
    32641 tcgcgccttg gcattgagca ggccgataac tgccgcaaaa gcacgccgat gcctgatttt
    32701 ataccgtccg cgttgtttaa cgacctctgc ctgccggagt tacagattaa cctgctaggt
    32761 gaagtcggtc aggaacccga tgcgcacagc atgccgattt tgcaggggat gaaagatttt
    32821 gccccggggc gtatcagcaa gcgctttgcc atcaaaaaca ttcgcgaatg ccactggcta
    32881 gtgccgaaaa aactcgagct gaaagatggt tcgcatccat tcccgattga tgattactgc
    32941 ccgccagaca aacgggagtc catgcccgat tgtcacatta ccactcgcac tggcatgcag
    33001 gttatccctt gcttccgcgc ctgggaagtg actgccagca cgccaccaga tgaccttaaa
    33061 ctgagtgaaa cctcaaacgc gtttcttaac tggcacagcg agatccgtcc acctcagaac
    33121 ggcatccctg cggaagtgcc atccaacaat gcctggcagg atattttcca gcaggtggag
    33181 ttttacagcc accagcagca ctgtccgatc gaagccgtgc gctttgccac cggatcacgt
    33241 gccaatatta aattcagcga ccagcgtgaa gacctgcaga ttgacttcaa atttgaacac
    33301 caaggcgaac ccgctgcgtt tggcttctcg ctgtgggtag atgcgataaa attccagtgt
    33361 cggttaccta attttgatct cgctagcatc agcaacaacc gtgaactggt ggccggattg
    33421 cgcacagcgc gcttcctgta tgaagtcagc cacgacgagg caatcagtgt taatactttc
    33481 ctcggcggtt ggctggcaga aactgtcctg gcaggtattg gcagcgaagc agtattgaaa
    33541 aactgcaccc cggagcaggc gttccgcgca atggaacaca acagcgcaag gatcgccttg
    33601 attgacgttc ctgctcgaat cttccagacg ttgtatgatg cgcagaccgg tgaagagata
    33661 gagcaggatc tacagcaaag cttgcgtgaa ctgttgtccc aggctccggt gatggcaaga
    33721 attgccgact gggtggaact gctgtggcaa ccgctggata acacctggtt ggagtggttg
    33781 accctcaact tcaccaacac actgggtgcg gcgctgctgc aaaccgctat gcagttgtgc
    33841 ccagatgccg acgacaacga cctaatcctt gacctcaacg gtgggccggt gcgcacttcg
    33901 ctgctcgcgc ctgaccagcg cgaaatctgg ctgtcggaaa ccaccgtggg cggtggcggt
    33961 atcattgaga agatccaaca gatttaccgt gaagatccgc gcagtttctt cgagttgcta
    34021 gactttaacc tcagtccagg cgactacgaa acaatggaca ataatgtctg gcacctgctg
    34081 caaaccatgg taaacccgac atcatccctg cctgcgtgta tgaacgaaat gcgccttgcc
    34141 aacgatcatg ccagccaggt tcaggcgcag cgcaacttgc tgggagaatt gcagcgcagc
    34201 ggctttatga ccagccacag cttcctgtcg gcgatcaaca cccgcctatt acggccgggg
    34261 accgatgcca gcagcgatgt ctttttactg caactgcaac aggattggcg acagcaggag
    34321 cagcgactgg gtattgaact accacagcgt gtctatgcct ttacctgtag tcagtccagc
    34381 gcgcttgacc agcaactaca acaagctagc caagggcagc acaacttgga gagttggcgt
    34441 ttaaatacct gtaatggcct actgtggcca cgtggccata ccattcgtga tagctggcta
    34501 acttggtaca acccttacag ctttgccggg ccaaccgagc gcctcctact ggcccatgtg
    34561 gtgcagcaca gttgtgctca ggtggcgctc agccaaccag actggatgca gcagtgtcac
    34621 cagcatctgg aaaataatgg taaatgcgaa ttactagccg aaccgggcga tgcaataaat
    34681 gaggccattg ctactctttt agtcacccca gtagaaatgt atgggttgtt cttctacccg
    34741 cgcgtcagtg ccctgcgccg ccacaacaat gacaccttcg ccatgattga aattccggag
    34801 gcgatccaat gaatacccgt cgtattttta aatccagaac ctcacgccag agtgaagttc
    34861 ttgatgtact cagctccttg ttggtagcgg agatcgctca gcccagcgcg gaattgtgga
    34921 tagtctcgcc gtggatcacc gacctcgacc tgctggataa tcgcaccggc cgtttcgact
    34981 acctcgaacc agcctgggga cagcgtcagg tgcagacctc agaactgctg gcgcgtgcgg
    35041 tagccaacgg cggtacgctt aaagtgatga ccaacgagac ccagcataat gcacgcttta
    35101 tccgccagtt aaccgaacgc gtcgccaact acggcatgct ggataacctg tacattggcc
    35161 agaaagaggt actgcatacc aaagggttcc tcggagatca tttcttccta agcggttcaa
    35221 tgaatctgac gatcggcggg atcgtgatca atgatgaaca gattaacttg accacagaca
    35281 aaaccgccat cgtgcaggcg ttgttagcat ttaacgactt ttaccaaccg gcacagggag
    35341 gtgtgcaatg aacagcgctg atagcgaaaa gttcctgcga gcctttttcc atagagaaaa
    35401 caatattatc tcttgggaaa aaatcgcggg tggcctgcta gaagcatcaa cccaacagcg
    35461 gttgaccccc tggcttgacg atgtccgcaa cggatgtttc ccggtgatcc tgccgcgcgt
    35521 agtaaagggc agcaatgaca aagtcacctg gtatgcaatg gccgatgagg aacgagacta
    35581 tgcggagttg cgcgaattat tagacgcgca cgtcggtacc tcgtggtcag actttaaccg
    35641 ccagcgcacg atgctggatc cgagcgaccc ggtggaaaaa gcgttgatag accactatag
    35701 cgatagagta tataaattta gctctctttc tctgtcgagg atcccggaga ttttcaatgg
    35761 catagagcgc ttacgccaac aactcgcaag ccgcccgagt taccagctca cacttctgcg
    35821 cccgcgtggc cgtattctgc gtgatattcg tgccgccttg cgccgtcgtg atgtgccgca
    35881 gactcgcctc tatctgcagg aactacgtga agctggtggc ataggccata ttaacgaact
    35941 gtttatcgaa ctgcgctgta tggctctgga aggtgacgcc aaaagcctgc tggattcgac
    36001 tcagttgcga caggtcttgg atatgccgca cccgttggtg ttggctgaag aagtaatgac
    36061 agtcttctat cagcagtttc tgctgaagta tgagcagttg agcgacctcg ccgcccaacg
    36121 acaagcattt aataatttgc tggtgaagaa cgtaccgcgt ctgttccagg tgacgcaggg
    36181 tataaacacg ccatcggcaa tcaaaaatat tctactgtgg ttactttctg acacacaaag
    36241 tgatccggca agactgaggg aacaggcaca acaagtggtt gccggtatga agggggcaac
    36301 agacgatgac cggcactgga tccgccggtt gttggaagca ttcccgaccg ttgcagtggc
    36361 ctccccaccg acggcgagca tcgatgaatt gcttgccaga gccgatgaat atcctgaaag
    36421 cgttctgaaa gagttactat tgctaccggt cagcgctcgc ggcgtagcca ttgctttgca
    36481 atgtgcctgg gtcgtaggca gtgcaggagc tgctgtgagt gctgtcagtt atctgcaaca
    36541 actggcacaa caagagcgcg acttgttact ggcgaaaccg gccttccagc gttattacac
    36601 tgccttacag ttgatgctgc catccaaacg aacagaacat gatactgcag gtatcaataa
    36661 ttggcaggac tggttgaagg aagtgttaaa taaccctcaa tggtcggggg cgatagaagc
    36721 ggtagaacag gcctgcggcc aatggaacgc agcggctttc cagcccgagg catttgtttc
    36781 gttgctggat aaaaccaaca actgcgccag tatggtgttg cgcgatgcca ttccagtact
    36841 gctcgagtgg ctggataacc atcaaacaag tgcttcctgg cagtctgtcc ggttagcgtt
    36901 gctgcaacaa ctggcgctgg acgacaatag ttctcgcgaa gatatcttta ctgcctgtga
    36961 actagcacgc ggttatttag agggcgatag taatgcgcac gattaccgcg aactaataga
    37021 aaacctgcag atgatgatcg agagttcagg taccaccagc gctagcgcct ggctggattt
    37081 gctggaactg ttcttggtct acccaactgc tgaccaactt gccagagaac aattattcaa
    37141 tctggtactc aacatgtttt accgcaaccc agcccgctat agtgaattgc agtggagcct
    37201 attggctcag tttgctggcg agtgcggact tgtctgtgaa attcccccac aaattttaga
    37261 ggacagtggg gaaaaaaatg atgaggttcg tgtcggatca acattgaatg acaaggtagt
    37321 gggcatttat acattgactg agtcggtagc acagcgtgtg aaaaaacaac tactagccga
    37381 ttatcctcag gccgatattc gcctcaacaa cgataaaggc ggctcaacca tgctgcgttc
    37441 attggctaga gaagcggatg tatttatttt tgcctggctt agttctaaac attctgctta
    37501 ttacgcgata aaggaagagc gaggagataa acctttattg caaccttccg gaaaaggcag
    37561 taccagtatg ctggactgca tacgtagtta tcttaaattg tagtaaaggt aaaaaactta
    37621 gctgtaacct ataacgtcac agctaagttc aatctcgggc tattcacccc gataaacaca
    37681 acccgcacta caggtttctt tcaccatgac agcactcaga attggcaact gtgttttaac
    37741 ctgattccat atccatttgg ccagtacttc gctggttggg ttttccaagc cagggatgtc
    37801 gttgagatag tagtggtcta ggcgatctag cgtcggcttg aaaatggcct tgagttcagc
    37861 gaaatcaata atccaacctg tgtgtttatc aacttcacca gttatctcaa ggcgcacgac
    37921 aaaagagtgt ccgtgtaagc ggccgcattt atggccttca ggaacattgg gaagacggtg
    37981 tgcggcttca aatgtgaaat ctttgtataa cgtagttttc atggtgacct cattttttgt
    38041 tatacagtaa caataagaag caagatttcc tagcatttaa gaatgagcat taacacgctt
    38101 gcgtattccg acccaaaccg gattgttttc gattgtgagc ctctttgcag gatgagcatg
    38161 caactcaatt ggacgttatc gctagccaca gccctacatc gactagtttc accgcttcct
    38221 acgtaagttt aaagattggc ggcaaaaaag agcttcagca ttctcatgac gctatttcag
    38281 ttggataact gaaatctccg ctacgacaac tcaggcaata actaactggt cttgcattgt
    38341 gcgcagagcc agtcggcttt actgaccctg aggatagcat tggggatgaa gtgctgtagc
    38401 cgtctggcta atcaggattt acatacgggc agtgctgtcg cccgttctcc gttagatcat
    38461 cgggccggtg ttcaaaccac gggcgttcgg taatgtattc aggatggtat tgcagcacgc
    38521 tactgctgtg gcaggtataa cgatcgtcag gggtggtctt cgcagtacgg gcaccggcgc
    38581 tcccgtcgaa agcgatatag gatttggcgt acatagtatt gttccttacc gccagacgac
    38641 acgcaggggc agacgtcccg gtgctagcag cgtggttgga tgtgaatggc aggtcaattt
    38701 agtaatatca gaagagggct aagcctgtgc tggatgtcat tactgtctgt tagttttcac
    38761 actatgaggt actgacgtaa aaagtcagag tgactggctg ctacggggtc tccctgttaa
    38821 tgggcgtgca gggacctcgt tgcagccgta gagcagcagg ccatgctttt gctgaatttt
    38881 ggtcatatac gccagtacct gtcggatgtt ggtgatactg tccggatcgc tgtaacgtac
    38941 cggaatgttg atattggcct cgtaatgctc tttaaactca catcggtgat accagccttc
    39001 ccggtcagtg atatcgctcc agtacaaacc ggcttgctgt gcccaggtat aggtattctg
    39061 agttttacta ccatccagcc agaacacgac gtgggcatga tagtgatggt cttctgtcca
    39121 ttcgataacc cagaagaaac cgaccaccgc ttcgagttgc atcatacggt tcatcagctt
    39181 tcggatatcc cattcgagct gctggtgatc ctgcaggaaa aacttagcgg tatgatcctg
    39241 gtaaaacaga tctgttcgga atgcccgcag gcaggaatag cgctctacca ttttgtcgat
    39301 atggttgttc aggagtgact gtagaaacca gtctggctcc catcgttgat tgtt
//
LOCUS       DAZUDJ010000044        39149 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.044, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000044 DAZUDJ010000000
VERSION     DAZUDJ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39149
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.044"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            282..701
                     /gene="umuD"
                     /locus_tag="ACHY1N_003010"
     CDS             282..701
                     /gene="umuD"
                     /locus_tag="ACHY1N_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HFS4045290.1"
                     /translation="MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLL
                     IQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLR
                     PTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR"
     gene            701..1969
                     /gene="umuC"
                     /locus_tag="ACHY1N_003011"
     CDS             701..1969
                     /gene="umuC"
                     /locus_tag="ACHY1N_003011"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase V catalytic protein"
                     /protein_id="HFS4045291.1"
                     /translation="MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEA
                     KALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSNRVMSTLEELSPRVEIYSIDE
                     AFCDLTGVRNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     GGVVDLSNLERQRKLMSALPVDDVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHF
                     NVVLERTVRELRGEPCLQLEEFAPTKQEIICSRSFGERITDYPSMRQAICSYAARAAE
                     KLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSRDIINAATRSLDAIW
                     QAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMTVMDTLNAKEGRGTLYFA
                     GQGIQQQWQMKRAMLSPRYTTRSSDLLRVK"
     gene            complement(2015..2545)
                     /gene="dsbB"
                     /locus_tag="ACHY1N_003012"
     CDS             complement(2015..2545)
                     /gene="dsbB"
                     /locus_tag="ACHY1N_003012"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HFS4045292.1"
                     /translation="MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLC
                     IYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFA
                     TCDFMVRFPEWLPLDKWVPQVFVASGDCAERQWDFLGLEMPQWLLGIFIAYLIVAVLV
                     VISQPFKAKKRDLFGR"
     gene            complement(2691..4232)
                     /gene="nhaB"
                     /locus_tag="ACHY1N_003013"
     CDS             complement(2691..4232)
                     /gene="nhaB"
                     /locus_tag="ACHY1N_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HFS4045293.1"
                     /translation="MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKV
                     REVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLF
                     YIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMG
                     WIATL"
     gene            4454..5173
                     /gene="fadR"
                     /locus_tag="ACHY1N_003014"
     CDS             4454..5173
                     /gene="fadR"
                     /locus_tag="ACHY1N_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000062 - fatty-acyl-CoA binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0019217 - regulation of fatty acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HFS4045294.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHE
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            complement(5225..6757)
                     /gene="ycgB"
                     /locus_tag="ACHY1N_003015"
     CDS             complement(5225..6757)
                     /gene="ycgB"
                     /locus_tag="ACHY1N_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HFS4045295.1"
                     /translation="MATIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYRLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARKYITEC
                     EERYGVDEVERLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRYPSEPQENLLYFMEKNAPLLESWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTEEDKYWFPDIAGSDWLETLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRNRLSSQYNLSNLEPNIQIWNVDLR
                     GDRSLTLRYIPHNRAPLDRGRKEVLKHVHRLWGFDVMLEQQNEDGSIELLERCPPRMG
                     NL"
     gene            7087..8385
                     /gene="dadA"
                     /locus_tag="ACHY1N_003016"
     CDS             7087..8385
                     /gene="dadA"
                     /locus_tag="ACHY1N_003016"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HFS4045296.1"
                     /translation="MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYM
                     ENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDA
                     GVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKF
                     RFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMV
                     VRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQ
                     LLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS"
     gene            8395..9465
                     /gene="dadX"
                     /locus_tag="ACHY1N_003017"
     CDS             8395..9465
                     /gene="dadX"
                     /locus_tag="ACHY1N_003017"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309712.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HFS4045297.1"
                     /translation="MTRPIQASLDLQALKQNLSIVRQAAPHARVWSVVKANAYGHGIE
                     RIWSALGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHS
                     NWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
                     AEAEHPDGISSAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPS
                     GQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAA
                     AAGTVGYELMCALALRVPVVTV"
     gene            complement(9851..11587)
                     /gene="cvrA"
                     /locus_tag="ACHY1N_003018"
     CDS             complement(9851..11587)
                     /gene="cvrA"
                     /locus_tag="ACHY1N_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006884 - cell volume homeostasis [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HFS4045298.1"
                     /translation="MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLI
                     TSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIAL
                     PAGLYPLLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERV
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKV
                     VVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDN
                     QLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYA
                     DVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLK
                     IGVRVAEEEAES"
     gene            complement(11682..12596)
                     /gene="ldcA"
                     /locus_tag="ACHY1N_003019"
     CDS             complement(11682..12596)
                     /gene="ldcA"
                     /locus_tag="ACHY1N_003019"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HFS4045299.1"
                     /translation="MSLFHLIAPSGYCIKQHAALRGIHRLTDEGHQVNNVEVIARRCE
                     RFAGTETERLEDLNSLARLTTPNTIVLAVRGGYGASRLLADIDWQALVARQQHDPLLI
                     CGHSDFTAIQCGLLAQGNVITFSGPMLVANFGADELNAFTEHHFWLALRNKTFTIEWQ
                     GEGPTCQTEGTLWGGNLAMLISLIGTPWMPKIENGILVLEDINEHPFRVERMLLQLYH
                     AGILPRQKAIILGSFSGSTPNDYDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVT
                     LPLGAHAILNNTREGTQLTISGHPVLKM"
     gene            12696..13307
                     /gene="emtA"
                     /locus_tag="ACHY1N_003020"
     CDS             12696..13307
                     /gene="emtA"
                     /locus_tag="ACHY1N_003020"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309714.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HFS4045300.1"
                     /translation="MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQ
                     KAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEP
                     TTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
                     RKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM"
     gene            complement(13309..14043)
                     /gene="ycgR"
                     /locus_tag="ACHY1N_003021"
     CDS             complement(13309..14043)
                     /gene="ycgR"
                     /locus_tag="ACHY1N_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HFS4045301.1"
                     /translation="MSHYHEQFLKQNPLAVLGVLRDLHKAAIPLRLSWNGGQLISKLL
                     AITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGAKVEFTVEQLQQSEYLQLPAFIT
                     VPPPTLWFVQRRRYFRISAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKP
                     AELQEGMRFAQIEVNMGQWGVFHFDAQLISISERKVIDGKNETITTPRLSFRFLNVSP
                     TVERQLQRIIFSLEREAREKADKVRD"
     gene            14244..14498
                     /gene="ymgE"
                     /locus_tag="ACHY1N_003022"
     CDS             14244..14498
                     /gene="ymgE"
                     /locus_tag="ACHY1N_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4045302.1"
                     /translation="MGIIAWIIFGLIAGIIAKLIMPGRDGGGFFLTCILGIVGAVVGG
                     WLATMFGIGGSISGFNLHSFLVAVVGAILVLGIFRLLRRE"
     gene            14676..15116
                     /gene="ycgY"
                     /locus_tag="ACHY1N_003023"
     CDS             14676..15116
                     /gene="ycgY"
                     /locus_tag="ACHY1N_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcgY"
                     /protein_id="HFS4045303.1"
                     /translation="MIQKINILDSSQSGVKNGADSEAVLAALIEHLELINPSGRLSQN
                     TRSAMLQLREEEWSEFFFWLLNSLECLDYVIINLTPESKKTLMSEHRNNIQVAIDALY
                     SQRRRKSPGDESETLTRRNDAIFGNHVWQTFAQYFPPGLEKPSV"
     gene            complement(15195..16892)
                     /gene="treA"
                     /locus_tag="ACHY1N_003024"
     CDS             complement(15195..16892)
                     /gene="treA"
                     /locus_tag="ACHY1N_003024"
                     /EC_number="3.2.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HFS4045304.1"
                     /translation="MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILL
                     GPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPK
                     EGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWD
                     SYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELL
                     AQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTP
                     RPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPHQLNTLRTTSIVP
                     VDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDL
                     KSHKVRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSVKSGQQWDAP
                     NGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGG
                     GGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQPSTKEAQPTP"
     gene            complement(17212..18630)
                     /gene="dhaM"
                     /locus_tag="ACHY1N_003025"
     CDS             complement(17212..18630)
                     /gene="dhaM"
                     /locus_tag="ACHY1N_003025"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415716.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019563 - glycerol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFS4045305.1"
                     /translation="MVNLVIVSHSSRLGEGVGELARQMLMSDSCKIAIAAGIDDPQNP
                     IGTDAVKVMEAIESVADADHVLVMMDMGSALLSAETALELLAPKIAAKVRLCAAPLVE
                     GTLAATVSAASGADIDKVIFDAMHALEAKREQLGLPSSDTKISDTCPAYDEEARSLAV
                     VIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLI
                     AKGPEAEEALIAFRQLAEDNFGETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSTL
                     TVEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSGHHTLLDDPELLAAASEL
                     LQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQ
                     FNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPVSHSALIARELGIGWICQQGEKL
                     YAIQPEETLTLDVKRQRFNRQG"
     gene            complement(18641..19273)
                     /gene="dhaL"
                     /locus_tag="ACHY1N_003026"
     CDS             complement(18641..19273)
                     /gene="dhaL"
                     /locus_tag="ACHY1N_003026"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFS4045306.1"
                     /translation="MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNR
                     GFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQATQARQSLT
                     LEELYQMFRDGVEGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASR
                     IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE"
     gene            complement(19284..20354)
                     /gene="dhaK"
                     /locus_tag="ACHY1N_003027"
     CDS             complement(19284..20354)
                     /gene="dhaK"
                     /locus_tag="ACHY1N_003027"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415718.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFS4045307.1"
                     /translation="MKKLINDVQDVLDEQLAGLAKAHPSLTLHQDPVYVTRADAPVAG
                     KVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTSPTPDKIFECAMQIDGGEGVLMI
                     IKNYTGDILNFETATELLHDSRVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLV
                     GAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIH
                     GEPGIDRRSFSSLDQTVDEMFDTLLENGSYHRTLRFWDYQQGSWQEEQQTKQPLQSGD
                     RVIALVNNLGATPLSELYGVYNRLTTRCQQAGLTIERNLIGAYCTSLDMTGFSITLLK
                     VDDETLALWDAPVHTPALNWGK"
     gene            20582..22501
                     /gene="dhaR"
                     /locus_tag="ACHY1N_003028"
     CDS             20582..22501
                     /gene="dhaR"
                     /locus_tag="ACHY1N_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415719.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase operon transcriptional
                     regulator DhaR"
                     /protein_id="HFS4045308.1"
                     /translation="MSGAFNNDGRGISPLIATSWERCNKLMKRETWNVPHQAQGVTFA
                     SIYRRKKAMLTLGQAALEDAWEYMAPRECALLILDETACILSRNGDPQTLQQLSALGF
                     NDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQALWNWAFCATPLFDSKGRLTGT
                     IALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDGVIS
                     WDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEATFE
                     SQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGKVSHTFAHMPQDDPQT
                     RRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGDAAL
                     AEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITRLDA
                     RRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPALVNN
                     KLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSDLPE
                     HLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRK
                     MKQHGIDAGQFKRRV"
     gene            complement(22601..25467)
                     /gene="ycgV"
                     /locus_tag="ACHY1N_003029"
                     /pseudo
     CDS             complement(22601..25467)
                     /gene="ycgV"
                     /locus_tag="ACHY1N_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415720.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(26308..27399)
                     /gene="ychF"
                     /locus_tag="ACHY1N_003030"
     CDS             complement(26308..27399)
                     /gene="ychF"
                     /locus_tag="ACHY1N_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFS4045309.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAVLEKCLPQLENAGMLRALDLSAEEKAAIRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTISFEDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDVMNFLFNV"
     gene            complement(27516..28100)
                     /gene="pth"
                     /locus_tag="ACHY1N_003031"
     CDS             complement(27516..28100)
                     /gene="pth"
                     /locus_tag="ACHY1N_003031"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFS4045310.1"
                     /translation="MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAK
                     FFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGV
                     AKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ"
     gene            28378..28656
                     /gene="ychH"
                     /locus_tag="ACHY1N_003032"
     CDS             28378..28656
                     /gene="ychH"
                     /locus_tag="ACHY1N_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HFS4045311.1"
                     /translation="MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAH
                     GAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYDKRCRRSDNRRHS"
     gene            complement(28711..30390)
                     /gene="dauA"
                     /locus_tag="ACHY1N_003033"
     CDS             complement(28711..30390)
                     /gene="dauA"
                     /locus_tag="ACHY1N_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HFS4045312.1"
                     /translation="MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCA
                     VMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIR
                     TLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATA
                     AIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL"
     gene            complement(30515..31462)
                     /gene="prs"
                     /locus_tag="ACHY1N_003034"
     CDS             complement(30515..31462)
                     /gene="prs"
                     /locus_tag="ACHY1N_003034"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFS4045313.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            complement(31613..32464)
                     /gene="ispE"
                     /locus_tag="ACHY1N_003035"
     CDS             complement(31613..32464)
                     /gene="ispE"
                     /locus_tag="ACHY1N_003035"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFS4045314.1"
                     /translation="MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIE
                     LRDDGDIRLLTPVEGVEHEDNLIVRAARLLIKTAADSGRLPTGSGANISIDKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKR
                     FREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLS
                     PLHRAML"
     gene            complement(32464..33087)
                     /gene="lolB"
                     /locus_tag="ACHY1N_003036"
     CDS             complement(32464..33087)
                     /gene="lolB"
                     /locus_tag="ACHY1N_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein insertase outer membrane protein
                     LolB"
                     /protein_id="HFS4045315.1"
                     /translation="MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQ
                     DVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEI
                     TYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK"
     gene            33301..34557
                     /gene="hemA"
                     /locus_tag="ACHY1N_003037"
     CDS             33301..34557
                     /gene="hemA"
                     /locus_tag="ACHY1N_003037"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041689438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008883 - glutamyl-tRNA reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HFS4045316.1"
                     /translation="MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQILADEVGAEVIALSEIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMA
                     WLRAQSASETIREYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAP
                     TKSLQQAARDGDNERLNILRDSLGLE"
     gene            34599..35681
                     /gene="prfA"
                     /locus_tag="ACHY1N_003038"
     CDS             34599..35681
                     /gene="prfA"
                     /locus_tag="ACHY1N_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFS4045317.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQ
                     LSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVME
                     GKLDMLIEPIIQEHQADQLAALSEQE"
     gene            35681..36514
                     /gene="prmC"
                     /locus_tag="ACHY1N_003039"
     CDS             35681..36514
                     /gene="prmC"
                     /locus_tag="ACHY1N_003039"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFS4045318.1"
                     /translation="MEYQHWLREAISQLQASESPRRDAEILLEHVTGRGRTFILAFGE
                     THLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPEQPCRILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKN
                     IHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIV
                     HIIEQSRNALVSGGFLLLEHGWQQGEAVRQAFILAGYHDVETCRDYGDNERVTLGRYY
                     Q"
     gene            36511..36903
                     /gene="sirB2"
                     /locus_tag="ACHY1N_003040"
     CDS             36511..36903
                     /gene="sirB2"
                     /locus_tag="ACHY1N_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="invasion regulator SirB2"
                     /protein_id="HFS4045319.1"
                     /translation="MTSFSTLLSVHLISLALSVGLLTLRFWLRYQKHPQAFARWTRIV
                     PPVVDTVLLLSGIALMAKAHILPFSGQAQWLTEKLFGVIIYIVLGFIALDYRRMHSQQ
                     ARIIAFPLALVVLYIIIKLATTKVPLLG"
     gene            36907..37716
                     /gene="sirB1"
                     /locus_tag="ACHY1N_003041"
     CDS             36907..37716
                     /gene="sirB1"
                     /locus_tag="ACHY1N_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="invasion regulator SirB1"
                     /protein_id="HFS4045320.1"
                     /translation="MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSL
                     AKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYRLSDALWLDLVLKNRQGSAVSLG
                     AVLLWVANRLDLPLLPVIFPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNI
                     SPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEI
                     RDRGLIYAQLDCEHVALNDLSYFVEQCPEDPISEMIRAQINNIAHKHIVLH"
     gene            37752..38606
                     /gene="kdsA"
                     /locus_tag="ACHY1N_003042"
     CDS             37752..38606
                     /gene="kdsA"
                     /locus_tag="ACHY1N_003042"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008676 - 3-deoxy-8-phosphooctulonate
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HFS4045321.1"
                     /translation="MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGN
                     EKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     AQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKG
                     FEELDTSK"
     gene            complement(38755..38862)
                     /gene="ldrA"
                     /locus_tag="ACHY1N_003043"
     CDS             complement(38755..38862)
                     /gene="ldrA"
                     /locus_tag="ACHY1N_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HFS4045322.1"
                     /translation="MTLAQFAMIFWHDLAAPILAGIITAAIVGWWRNRK"
BASE COUNT         9714 a         9763 c        10067 g         9605 t
ORIGIN      
        1 gggcgggatg cgtcaatgtc tttatttcta ttaatatgat aaatatcaaa caatgtttaa
       61 tgtcattatg gcgaatgctt ctattctatt tttttgccgg gtgatatttt tcatttctgc
      121 tggatgagcg tcgtcgccag aaggccacgt gagcacagga taagagaacg aaaaatcagc
      181 agtctatgca gcgacaaata ttgatagcct gaatcagtat tgatctgctg gcaagaacag
      241 actactgtat ataaaaacag tataacttca ggcagattat tatgttgttt atcaagcctg
      301 cggatctccg cgaaattgtg acttttccgc tatttagcga tcttgttcag tgtggctttc
      361 cttcaccggc agcagattac gttgaacagc gcatcgatct gaatcaactg ttgatccagc
      421 atcccagcgc gacttacttc gtcaaagcaa gtggtgattc tatgattgat ggtggaatta
      481 gtgacggtga tttactgatt gtcgatagcg ctattaccgc cagccatggt gatattgtca
      541 tcgctgctgt tgacggcgag tttacggtga aaaaattgca actacgcccg acggtacagc
      601 ttattcccat gaacagtgcg tactcgccca ttaccatcag tagcgaagat acgctggatg
      661 tctttggtgt ggtgatccac gtcgttaagg cgatgcgctg atgtttgctc tctgtgatgt
      721 aaacgcgttt tatgccagct gtgagacggt gtttcgccct gatttatggg gtaaaccggt
      781 ggttgtgcta tcgaataatg acggttgcgt tatcgcccga aacgctgagg caaaggcgct
      841 gggtgttaaa atgggcgatc cctggttcaa acaaaaagat ctgtttcgtc gctgtggcgt
      901 ggtttgcttt agcagcaatt atgagcttta cgcagacatg agcaatcggg tgatgtcgac
      961 gctggaagaa ctatcgcccc gcgtcgagat ttacagtatt gatgaggcat tctgcgatct
     1021 gacaggtgtg cgtaattgtc gcgatctgac tgattttggc agagaaattc gcgcaacggt
     1081 gctacaacgt acccatctta ctgttggtgt ggggatcgcc cagaccaaaa cgttggctaa
     1141 gcttgccaat catgcggcaa aaaaatggca gcggcagacg ggtggggtgg tggatttatc
     1201 aaatctggaa cgccagcgta aattaatgtc tgctctcccc gtggatgacg tctgggggat
     1261 tggacggcgg atcagcaaaa aactggacgc gatggggatc aaaaccgttc tcgatttggc
     1321 ggatacagat atccggttta tccgtaaaca ttttaatgtc gtgctcgaaa gaacggtgcg
     1381 tgaactgcgc ggcgaaccct gtttgcaact ggaagagttt gcaccgacga agcaggaaat
     1441 tatctgttcc cgctcgtttg gtgaacgcat cacggattat ccatcgatgc ggcaggccat
     1501 ttgtagttac gctgcccggg cggcggaaaa acttcgcagc gagcatcaat attgtcggtt
     1561 tatctccaca tttattaaga cgtcaccatt tgcgctcaat gaaccttatt acggcaatag
     1621 cgcgtcggta aaactgctga cgcccactca ggacagcagg gatatcatta acgctgctac
     1681 gcgatctctg gatgccatct ggcaagcggg ccatcgctac caaaaagcgg gcgtgatgct
     1741 gggggatttc ttcagtcagg gagtcgcgca gctcaattta ttcgatgaca acgcaccgcg
     1801 ccccgggagt gagcaattga tgacggtaat ggatacactg aatgctaaag agggcagagg
     1861 aacactctat tttgccgggc aggggatcca gcaacaatgg cagatgaagc gtgccatgct
     1921 ttcaccacgt tatacaacgc gaagttctga tttactgcgg gtcaaataaa tatagcggca
     1981 ggaaaaaagc gctcccgcag gagcgctgaa gggattagcg accgaacagg tcacgttttt
     2041 tcgctttaaa cggctgggaa atcaccacca gcaccgcgac aatcaggtaa gcgataaaaa
     2101 taccgagcag ccactgcggc atttccagac ctaaaaaatc ccactgacgc tcggcacaat
     2161 cgccagaggc gacaaacact tgcggcaccc atttatccag cggcagccat tccgggaaac
     2221 gaaccataaa atcacaggtg gcaaacggcg aaggatagag ctgaagcatg gtgtgctcgt
     2281 aagttaactg cacaccgcgg aacgcactat acaaccagat aaccatcgct acataacgca
     2341 gcggagtttt cggggcgatc gcgccaatca gcgcagcacc cagaacgccg aataacgcac
     2401 aacgttcata aatacagagc acgcaaggtt tcagtaacat cacatgctgg aaccacagcg
     2461 ccgtcagttc cagtgccaga gcagtaaacg ccatcaacag ccacgcgccc cggccttgtg
     2521 aacattggtt caaaaatcgc aacataatca tttccctgca atatgcatag agtgcgcagt
     2581 ttaaaccaat tcattcgctg cgccaccagg aggcagcaaa aataggaagc aattggacaa
     2641 ttatcgggcg aaaaggcaaa ccgggcattt atatgcccgg taagttgtta tcaaagcgtt
     2701 gctatccagc ccatttgcat aaaccattcg gttacagggg caagcgtaaa ctcgacgcag
     2761 agcaagccga cgagtgtcag tacgagggtg taaggcaggg ccatccacac catgcggcca
     2821 taagagaggc gaatcaatgg cgcgagtgca gaggtcagca ggaacaggaa cgcagcctga
     2881 ccgttcggcg tagcgacgga gggcagattg gtaccggtat taatggcgac cgccagcagc
     2941 tcgtattgct tcaacgtgat agcgccactt tccattgccg ctttcgcttc gttgatataa
     3001 atcgtcccca cgaagacgtt atccgaaatg gatgacagca gaccgttgaa aatatagaac
     3061 agcgacagct gagcatgttc cgatgcctgc aacacaaact gaataattgg cgaaaacagt
     3121 tgttggtcga taatcaccgc gactaccgag aaaaacaccg tcaacagtgc ggtgaatggc
     3181 agagattcgg tgaaggcttt accgatagca tgttcatcgg tgacaccggt caatgatgtc
     3241 gccagaataa tgactgacaa accaatcaag ccaacttccg ccagatgcaa cgccagcgca
     3301 gtcaccagcc agacgccaat aatcgcctgg acaatcagac ggattttatc ctgacgggta
     3361 cgctggtggc ggctttgatc gtcaaactgt tgcaacactt cgcggacttt ctccggcagc
     3421 gtttcaccgt agccaaacca acgcagcttc tctaccagca ggcaggttaa caggccacaa
     3481 atcagaaccg gaacggtcac cggcgacatg cgcaggaaga aatcgccaaa atgccagcca
     3541 gccgctttag cgatgatcag gttctgtggt tcgcccacca tggtcatcac gccgcctaat
     3601 gcagtgccga caccggcatg catcatcagg ctacgcagaa agccacggaa ctgttccaga
     3661 accactttgt aatgcttgtc gatatgacta tcgtcttgca ggtcggtatc ttcggtacgg
     3721 gaagaggcta cgcggtgata aataccataa aaaccgacag caacgctgat caccaccgcc
     3781 acgacggtta aggcatcgag gaacgcggag aggaacgctg ccgccacgca aaaagagagc
     3841 gacagcagca ttttggagcg aatgcttaac agcaaacggg taaatatgaa cagcaacagc
     3901 tgtttcataa aatagatacc cgccaccata aacatcaata acagcaagac ttcaagattt
     3961 gccgccacct cttcacggac gtgttccgcg ctggtcatgc cgatgaatac cgcttcgata
     4021 gccaacagac caccggggag cagcgggtag catttcaggg ccatcgccag agtgaaaata
     4081 aattccgcta ccagcaacca gcccgcgacg aaagggctga tgaggaaaat taacgggttt
     4141 acgattaaga aaatgatgag ggcgagtttg taccagtcgg gggactggcc caaaaaattg
     4201 cgccatagcg cgcggcccca ggagatctcc atgatggttt cccttacctt acaaataatc
     4261 aatgatgttt ttatgtttaa acgcaaagct taacggtcag gcaggagtga ggcaagtctt
     4321 gatagtcaag gggaaagaga tgcggaaaat gaagccttga tccctttttt cttctttttg
     4381 tctgctatca gcgtagttag ccctctggta tgatgagtcc aactttgttt tgctgtgtta
     4441 tggaaatctc actatggtca ttaaggcgca aagcccggcg ggtttcgcgg aagagtacat
     4501 tattgaaagt atctggaata accgcttccc tcccgggact attttgcccg cagaacgtga
     4561 actttcagaa ttaattggcg taacgcgtac tacgttacgt gaagtgttac agcgtctggc
     4621 acgagatggc tggttgacca ttcaacatgg caagccgacg aaggtgaata atttctggga
     4681 aacctctggt ttaaatatcc ttgaaacact ggcgcgactg gatcacgaaa gtgtgccgca
     4741 gcttattgat aatttgctgt cggtgcgtac caatatttcc actattttta ttcgcaccgc
     4801 gtttcgtcag catcccgata aagcgcagga agtgctggct accgctaatg aagtggccga
     4861 tcacgccgat gcctttgccg agctggatta caacatattc cgcggcctgg cgtttgcttc
     4921 cggcaacccg atttacggtc tgatccttaa cgggatgaaa gggctgtata cgcgcattgg
     4981 tcgtcactat ttcgccaatc cggaagcgcg cagtctggcg ctgggcttct accacaaact
     5041 gtcggcgttg tgcagtgaag gcgcgcacga tcaggtgtac gaaacagtgc gtcgctatgg
     5101 gcatgagagt ggcgagattt ggcaccggat gcagaaaaat ctgccgggtg atttagccat
     5161 tcaggggcga taatcccttc cgtttaaaga gcaaacccct caaacgaggg gttttttgtt
     5221 gtttttacag atttcccatt cttggcgggc aacgttccag caactcgatg ctgccgtctt
     5281 cgttttgctg ttcgagcatc acatcaaatc cccacaggcg atgcacatgc ttcagcactt
     5341 ctttgcgccc ccgatccagc ggtgcgcgat tatgtggaat gtaacgcagc gtcagcgaac
     5401 ggtcgccgcg caaatccacg ttccagatct gaatattcgg ctccagatta cttaagttat
     5461 attgcgacga taaccggtta cggatctccc gataaccttc ttcattatga atagcggaaa
     5521 tctccagata attatgccga tcatcatcca gcacggtgaa gaagcggaaa tcacgcatca
     5581 ctttcggtga cagaaactgg ctgataaaac tctcatcttt gaaatcacgc atcgcgaaat
     5641 gcagcgtttc cagccagtcg gaaccggcga tatccgggaa ccagtatttg tcttcttccg
     5701 ttggcgactg acaaatccgt ttaatatcct ggaacatggc gaacccgagg gcatatgggt
     5761 tgatgccgct gtaccacggg ctgttatagg ggggctggaa gaccacattg gtgtggctgt
     5821 gcaaaaactc cagcataaaa cgttccgtta ctttcccttc atcatacaga tggttaagga
     5881 tggtatagtg ccagaaggtc gcccagcctt cgttcatcac ctgagtctgt ttttgcggat
     5941 aaaaatactg gctcacctta cgcacaatac gcaggatttc acgctgccat gattccagca
     6001 gtggcgcatt tttctccata aaatagagca ggttttcttg tggttcggac ggatagcggc
     6061 gcgcttcagc aaccgttttc tcttcctcgc gcttcggcag ggtacgccag agcatattga
     6121 cctgactttg tagatactct tcgcgacttt tctgccgggc tttctcttct tgcagcgaga
     6181 ttttttgcgg gcgtttgtac cggtccacgc cgtagttcat cagcgcgtgg cacgagtcca
     6241 gaagccgttc tacttcatca acgccataac gttcttcgca ctcggtaata tatttacggg
     6301 caaaaatcag ataatcgaca atcgaactgg cgtcggtcca actgcggaat aagtaattgt
     6361 ttttaaagaa agagttatgc ccatagcagg cgtgtgccat caccagcgcc tgcatggtaa
     6421 tggtgttctc ttccatcagg taagcgatac acgggttaga gttaatgacg atttcatagg
     6481 ccagtccttg ctgaccgtgc ttatacagcc gttcagtctc gataaacttt ttaccgaatg
     6541 accagtgcgg atagttaatt ggcatgccga cgctggagta ggcatccatc atctgttctg
     6601 aggttatcac ttcaatctgg tgcgggtagg tatccagccg gtagagtttc gccacccggt
     6661 ctatctctgc cagataaaca tccagcaggt cgaacgtcca gtcgggtcca tcgctcaaac
     6721 gtgtggtgtc cttattcata gaatcgatcg tcgccatacg cgcacctcat tgttgtcggc
     6781 gctctctgtg tggagcacct catttcaagc atagaacacc tgttaaaaac cgcgtcgccg
     6841 gagaattttt ttctttgcga tttcttatta tcagagtgcc actaatccgc ttctgaacgg
     6901 aattttatgc tggataaaaa gggcgttcag caggagatac taaagacgcc atattgccgc
     6961 agagtcaggg agatgtgagc cagctcacca taaaaaagcc gtatgttgaa taatattttc
     7021 aactgagtta tcaagatgta attagattat tattctttta ctgtatctac cgttatcgga
     7081 gtggctatgc gagttgtcat actgggaagt ggtgtggtag gcgttgccag cgcctggtac
     7141 ttaaatcagg caggacatga ggtcaccgtc attgatcggg agccgggggc cgccctggaa
     7201 accagcgccg cgaatgccgg gcaaatctcc cccggatatg ctgcaccgtg ggcggcacca
     7261 ggtgtgcctt taaaagcgat caaatggatg ttccagcgcc atgcgccgct ggcggtccgt
     7321 ctcgacggta cgcagtttca gttgaaatgg atgtggcaaa tgttacgtaa ctgcgacacc
     7381 agccactaca tggaaaacaa agggcggatg gtgcgtctgg cggaatacag ccgtgattgc
     7441 ctgaaagcat tgcgcgccga aaccaatatt cagtatgaag ggcgtcaggg tgggacgctg
     7501 caactgttcc gtaccgaaca acagtatgaa aatgcgaccc gcgatatcgc cgtgctggaa
     7561 gatgccggcg taccgtatca gctgctggaa tccagccgcc tggcggaagt ggagcccgcg
     7621 ctggcagaag tagcgcacaa actgacgggt ggtctgcaac tgcccaatga tgaaaccgga
     7681 gactgccagc tgtttaccca gaatctggcg cggatggcag agcaggcggg ggttaaattc
     7741 cgctttaata cgcccgttga ccaactgctt tgcgacggcg agcaaatcta cggcgtgaag
     7801 tgtggcgatg aagtgattaa ggccgatgcg tatgtgatgg cgtttggttc ttactcgacg
     7861 gcgatgctca aaggcattgt tgatattccg gtgtatccgc tgaaaggcta ctcgctgact
     7921 attccaattg cgcaggaaga tggtgcgcca gtatccacta ttcttgatga aacctacaaa
     7981 atcgccatta cccgtttcga taaccgcatt cgtgttggcg gaatggcgga aattgttggt
     8041 tttaacaccg agctgttgca accgcgtcgt gaaacgctgg aaatggtggt tcgcgatctc
     8101 tatccacgcg gcggtcatgt cgagcaggcg actttctgga cgggtttgcg cccgatgacg
     8161 ccagacggta cgccggttgt cgggcgtaca cgctttaaaa atctgtggct gaataccggt
     8221 cacggcacgc tcggctggac gatggcttgc ggttccggtc agttgttaag cgatctgctc
     8281 tctggtcgca cgccagcgat cccatatgag gatctaagcg tagcgcgcta cagccgtgga
     8341 tttacgccat cacgtccggg ccatttacat ggcgcacaca gctaaggaaa cgagatgacc
     8401 cgtccgatac aggccagcct cgatctgcag gcattaaaac agaatctgtc cattgtccgc
     8461 caggccgcgc cgcacgcgcg cgtctggtcg gtggtaaaag cgaacgctta cgggcatggt
     8521 attgagcgta tctggagcgc gctcggggcc accgatggct ttgcattact taacctggaa
     8581 gaggcaataa cgttacgtga gcgcggctgg aaggggccga tcctgatgct ggaaggattt
     8641 ttccatgctc aggatctgga gatttatgac cagcaccgcc tgaccacctg cgtacacagc
     8701 aactggcagc tcaaagcact gcaaaatgcg cggctaaaag caccgttgga tatttatctt
     8761 aaagtgaaca gtgggatgaa tcggttgggc ttccagcccg atcgcgtgct taccgtctgg
     8821 cagcagttgc gggcaatggc gaatgttggc gagatgaccc tgatgtcgca ttttgccgaa
     8881 gcggaacatc ctgatggaat ttccagcgcg atggcgcgta ttgagcaggc ggcggaaggg
     8941 ctggagtgtc ggcgttcgtt gtccaattcg gcggcgactc tgtggcaccc ggaagcgcat
     9001 tttgactggg ttcggcctgg cattattttg tatggcgctt cgccgtccgg tcagtggcgt
     9061 gatatcgcca ataccggatt acgtccggtg atgacgctaa gcagtgagat tattggtgtc
     9121 cagacgctaa aagcgggtga gcgtgtgggc tacggcggtc gctatactgc gcgcgatgaa
     9181 cagcgaatcg gcattgtcgc cgcagggtac gccgacggtt atccgcgcca cgcgcctacc
     9241 ggtacccctg ttttagtgga cggcgtgcgc accatgacgg tggggaccgt ctcgatggat
     9301 atgctggcgg tcgatttaac gccttgcccg caggcgggga ttggtacgcc ggttgagctg
     9361 tggggcaagg agatcaaaat tgatgatgtc gccgccgctg ccggaacggt gggctatgag
     9421 ttgatgtgcg cgctggcgtt acgcgtcccg gttgtgacag tgtaacttgt tgtaagccgg
     9481 atcggagaca gcgtcttctg gttgcgaaaa aatcatccat ccggctggtc agcaactgta
     9541 gttgttaatg tgacagagcc attgcccatg atagtgtcca ttaaaagaat ggacactatt
     9601 tccccggaac ctgaactcac cgcacaggcg ttctacataa aacgcttacg cttcattgtt
     9661 gactcgaact cgacttcaga taaatcacgc tttacccttg atggagcctg tacatagatt
     9721 tgtgtaattg cctgattttg atatgttcaa ttcaacatca aatgaaggtt aaattatgga
     9781 cgacaaacaa ttgcaggctc aggctgcgtt cagcaaagca tcgcaaccgg cgatagatgc
     9841 ttcattaaat ttaagattca gcttcctctt cagccacccg tacgccaatc ttcaacactt
     9901 cattatcttc tttctcggcc accgtccaga tcatcccggc aaactctacc tggtcaccga
     9961 caaccggtgc cgcgcctaac aactgctgga caatttcacc cagcgtttgc tgcttatcac
    10021 gatattctcg cccgtcttcc aggccatata tcagcgcaac atcagcatat ttggcgctgg
    10081 cttcgagaat gaagtcacca aagaagcgtt gatccagcgc gaccggcggc gactggctga
    10141 acagtttacc gagcgccgga agatcgcgtt cccgaccaat tacacacaac acatcgcctt
    10201 cgcgcagtcg ggtgctgccg gtaggatgaa gcaactggtt atcacgaaac agtgccgcaa
    10261 tacgcgtctc ttttggcata tgcaaatcgc gcagtgccgc gcccacgcac catttatcgg
    10321 cactcaattg ataaacaaac tgctcccacg gattttccgg atgaatatcc aggccaacgc
    10381 gtgacaccgg acgtcccact ggcggaacca ccactttggc ttttttagcc gcccacgaga
    10441 gtgatgttcc ctgcaagagc agtgaaacca gaaccacaaa gaaggcgaca ttaaagaaca
    10501 gacgtgcatt ctccagcccc gccatcatcg ggaacacggc caggatgatt ggcaccgcgc
    10561 cgcgtaatcc tacccagctg ataaacacgc gctcacgcag attgaaaccg cggaagggga
    10621 gcaatccagc aaataccgaa aggggacggg cgaagaatat catccatgcc gacaaaatga
    10681 gcgccggaat ggcaataggc agcagatcgc ttgggttaac caatagcccc agcaccagga
    10741 acatggcgat ttgcgccagc caggcgaggc cgtcgaaatt ttgcaggatg ccgtagcggt
    10801 tgcgaatcgg ccgattaccc agcagaaaac cgcacagata aacagccaga atgccgctgc
    10861 cttccagcgc cgtggttaaa gcaaaaatta aaataccgcc gcttaatgcc agcaatggat
    10921 ataatccggc aggcagggcg atgcgattaa tcatttgcag cagtaaataa ccaccgccaa
    10981 gtccgatgac aatcccgagg ccaaattgct gcagaatatc gaccacgaac atccaactga
    11041 cactgctttc atgttgctgg atcatcgcaa tcagggtaat cgtcagaaag accgccattg
    11101 gatcattact gccggattca atttccagcg tcgagccaac acgttcgtta agccccttac
    11161 cacccagcag agaaaagacc gctgcagcat cggtagagcc gacgatagcg ccgattaata
    11221 agccttcaat caaatcaaga ttaaacagcc acgccgccat catgccggtt aaaccagagg
    11281 tgataagcac gcccagcgtc gccagcgaca gtgccggtcc taacgccaca cgaaaggaac
    11341 tggcctgagt gcgcatcccg ccgtcgagca aaataatcgc cagtgccagg ttacttacca
    11401 tgtaggcgaa ggggtaatta tcaaacggga taccgccgac gccatcgact cctgccagca
    11461 tgccgatcgc cagaaaaata accagaatag gaatgccaag acgggaagaa aatgaactaa
    11521 gtaatatact gctggtgaca aggatggatc ctaagatgaa aaggctaatt attgttgtgg
    11581 catccaacgg tcggttactc ctgattacgc tgtctcttat ataaacccta ccatattagc
    11641 ggcagagaca gcgttttact tagccctgaa gcgtgatttt tttacatttt aagaacagga
    11701 tgaccgctaa tcgtcaactg agtgccttcc cgggtgttat tcagaatggc atgtgcgccc
    11761 aacggcagcg taaccgtgcg ttgttcatga ccaaaatcga ggccggtaat gagtggaatc
    11821 gacaggcggg aacgcaaaaa cgcgtacact gactccaggt tgtaacctgc gtcataatca
    11881 ttgggcgtgc tgccgctaaa gctaccgaga ataatcgcct tctgacgtgg caaaattccc
    11941 gcatgataga gctgcaacag catacgttcg acgcggaaag ggtgctcgtt aatatcttcc
    12001 agcaccagaa taccgttctc aatttttggc atccacggtg taccaatcag tgaaatcagc
    12061 atcgcaagat tgcctcccca caacgtgcct tcggtctgac atgtcgggcc ttccccttgc
    12121 cattcaatgg tgaaggtttt attgcgtaac gccagccaga aatggtgctc ggtaaaggcg
    12181 ttcagttcat ccgcaccaaa gtttgctacc agcatggggc cgctaaaggt gatgacattg
    12241 ccttgcgcca gaagaccgca ctgaatggcg gtaaaatcgc tatgtccgca aatgagtaac
    12301 gggtcatgtt gttggcgagc caccagtgcc tgccagtcaa tatctgccag taaacgactg
    12361 gcaccgtaac cgccgcgtac agccagcacg atggtgttgg gggtagtcag tctggcaagg
    12421 gaattgagat cttccaggcg ctccgtttcc gtacccgcaa aacgctcaca acgacgggca
    12481 ataacctcga cgttattgac ctgatgcccc tcgtcggtaa ggcgatggat accacgcagc
    12541 gcggcgtgct gtttaatgca gtaacccgat ggggcaatta agtgaaacag agacatggca
    12601 attccttgct gacaacagaa acgaaatgta tatcatgccg cttaggtgtg ccgttgtcac
    12661 ctcaacggcg attccaggct ataaggatag aagaagtgaa attgagatgg tttgcctttt
    12721 tgattgtgtt attagcgggt tgttcatcaa agcatgacta tacgaacccg ccgtggaacg
    12781 cgaaagttcc ggtgcaacgt gcgatgcagt ggatgccaat aagccagaaa gccggtgcag
    12841 cctggggcgt cgatccacaa ttgatcacgg cgattatcgc tattgaatcg ggtggtaatc
    12901 cgaacgcggt gagtaaatcg aatgccattg gtttgatgca gttaaaagct tcaacctccg
    12961 gacgtgatgt ttatcgccgt atgggctgga gtggtgagcc gacgaccagc gagctgaaaa
    13021 atccagagcg taatatttca atgggggcgg cttacctgaa tattctggaa accggcccgc
    13081 tggcaggcat tgaagatccg aaggtactgc aatatgcgct ggtggtgtca tacgctaacg
    13141 gggcaggtgc gctgctacgg actttctcgt cagatcggaa aaaggcgatc agcaaaatca
    13201 acgatttgga tgctgacgag ttcctcgatc acgtagcgcg aaatcatcct gcgccgcagg
    13261 ctccgcgcta tatctacaaa cttgagcagg cactggacgc gatgtaaatc agtcgcgcac
    13321 tttgtccgct ttttctcggg cttctcgctc gagagagaaa ataatccgct gtaattgccg
    13381 ctccaccgtc gggctgacgt taagaaaacg gaagctcaga cggggagtgg tgatggtttc
    13441 attcttgcca tcaatcactt tgcgctcgct gatggagatt aactgggcgt caaagtgaaa
    13501 aacaccccat tgccccatgt tgacttcaat ctgagcgaag cgcatgcctt cttgtaattc
    13561 ggcaggcttt gctgtttcca gtaatgcgcc catgccgcct aacgacaaat catacaggcg
    13621 gaaacgtaac gtactgttat ccgccagttt ggtctggcaa aaataaggcg gatggagtgg
    13681 ggcggagatg cggaaatatc ggcgtcgttg tacaaaccat aaggtgggag gcggtacggt
    13741 gataaatgcc ggaagctgca agtattcact ctgctgtagt tgttcaacag taaactcgac
    13801 tttcgcaccc tgagtttcgg cggtaatggt aatgtgctgt gcctttagca cggcgatgtt
    13861 gtcttcggct tgactgccga aatccagcac cagtttatcc ggggttattg ccagtaattt
    13921 gctgatcagc tgcccgccat tccaactgag acgcaaagga attgcggctt tgtgcaaatc
    13981 gcgtaacacg cccaggacgg ctaacggatt ttgtttcagg aactgctcat ggtaatgact
    14041 cacgcggaaa aactcctgac tgacaaactg tctttggttt atcggtcaca gttaacaaaa
    14101 cttaatacaa atgcgtgaat attttttaca tgttgttctt aaatcagccg acatacgccc
    14161 agcatcgatc ccgcccttgc ctatacttag agcgttgatg taagcatttc ttgcgtccga
    14221 ttcatcgaaa cgagggcctg aacatgggaa ttattgcctg gattattttt ggcctgatag
    14281 ccggcattat cgccaagcta atcatgccgg ggcgtgatgg tggtggattt ttcctgacct
    14341 gtattctcgg gatagtcggt gcggtggtcg gcggctggct ggcgaccatg tttggcattg
    14401 gcggctccat cagtggtttt aatctgcaca gcttcctggt ggcggtggtg ggagctattc
    14461 tcgttctggg catattccgc ctcctgcgaa gagaataaga ttttcataag gcggatagcg
    14521 atacagatgc cgctatccgc tttcacatca gaacgtatac tcgacacctg ctttacgggt
    14581 gaaaaaaatc aatatagcac ttcgatatcc gataaagtcg gttcccggta acaacaacag
    14641 aatccttttt taattattgt ttcgttgttt ttggtgtgat tcagaaaata aatattttag
    14701 acagtagcca gtcaggcgtt aaaaatgggg cggatagtga ggcggttttg gctgcgctta
    14761 ttgaacattt agaattgatc aatccttctg gcagattaag ccaaaatacc cgttcggcaa
    14821 tgcttcagtt acgcgaagag gaatggtctg aattcttttt ttggttgcta aattctctgg
    14881 agtgtctgga ttatgtgatt attaatttaa ctccagaaag caaaaaaacg ttgatgagtg
    14941 aacaccgtaa caatattcag gtagcaattg atgctttata tagccaacgt cggcgtaaat
    15001 cgccgggtga tgaaagtgaa acacttaccc gtagaaatga cgctatcttc ggcaaccacg
    15061 tgtggcaaac atttgcgcaa tacttcccgc caggacttga aaaaccgtct gtgtagaaaa
    15121 aaccatagct atggtgttat ctgccgacaa cgccatccgg agaagccgaa tgacgttgtc
    15181 ggagtaagcg ctggttaagg tgtgggttgt gcctctttgg ttgagggttg cgtcgttgct
    15241 gacttaacgg tcggacgcgt cgccggaaca ttgtcacacg gttgctcttt cgggcagatc
    15301 aaatccagca ttttcagcgt cacgccattg gtccagccaa agccatcctg taatggatat
    15361 tcgccaccgc cgccccccgt tccggtggtg ctgacatcat atttttccac cagctttttc
    15421 tcccggtcat aggtgtgctg aacattggtc aggaagtgcc agctaatgtc catcgccacc
    15481 tctttttgcc cgtagttttg taatccttct gtcgcgaccc actgtaacgg tgcccagcca
    15541 tttggcgcat cccattgttg cccacttttc accgacgtgg tgttcaggcc gccgggttgc
    15601 agcagatgtg ttttcgtcgc cgtcgccatt ttgttggcgc gatctttcgc tgccgcattg
    15661 acgtacagcg ggaacagggc ggccgcggtt aactgattgc gcactttatg acttttcagg
    15721 tcgtaatcgg cataccagcc ttgttgatcg ttccacatgt atttttcgat ccctttttga
    15781 cgggcatttg ccagcgtttc gtactggttt gccatcgcgt tatctccggc agctttgctg
    15841 gcgcgggcga ggattttttc cattttaaac atcaggctgt tcagatcgac cggtacgatg
    15901 ctggtggtgc gtaaggtatt tagttgatgc gggttgtcca tccagcgcga gctgaaatcc
    15961 cagccagacg cagcggcaga gcgcaggtcg cggtaaattt cagtggcagg tcgattcgga
    16021 ttgcttttgg cggtggcaat atcttccacc catgactctg gtcgtggcgt atcgcgatcg
    16081 tcccagtagc ggttgagaag ggtaccatcc tgaagtttta caacgcgttt ttcctgttgt
    16141 ccggcttgca ggttttcaac accgtccatc cagtaagcat attctttttg catttgcggc
    16201 aggtattgct tcaacgcggc atcgccttca tgctgcgcca gtaactctac catcagggca
    16261 aagaagggcg gttgcgagcg gcttaaatag taactgcggt tgccgttggg aatatgaccg
    16321 taagtgtcta tttcatgagc aaaattggcc accatatccg cgactttatc ccagtgaccg
    16381 ctttcggcaa gtcctaacat ggtgaagtaa ctgtcccagt aatatacctc gcgaaaacgt
    16441 ccgcccggca cgacataagg ttccggcagc ggtaacagag aatcccattt ttcggtgttt
    16501 tcggtagaac gcgttaatac cggccaaagt ccgtcaatat gttcgcgcag tgactgcccc
    16561 tctggcggaa catatttctc gccttctttc ggcagggtga aattgacgtt aacgaaatgg
    16621 cgcagatcaa atccgctctg gttttgctgc atccgataat cagcaaggat catcagcgga
    16681 tcgctgttcg gcacggcatc ggcaaaggtt ttttggtccg gaaaaagttt ggcgttttgc
    16741 acatcattaa acagcggccc taataaaata tcaggcggct gtggtgttac cggtgtttct
    16801 tctgcctgca ccgatagcgc agcgaaacac aaaaagatac aggctggaat taacgccatt
    16861 ttttgcgggc gagaaggtgc gggggatttc atcaatcatt ctcctttggc gaaaccgaat
    16921 aaaacggtat tcaagtatca gaaaacctta gttcaggatc gcactagctg catgatcgaa
    16981 atctcattct gcgaactgtc aggcatttta gaaaagggaa ttaaagggat aaataacggc
    17041 gaaatagagt gatcaaataa cgtctgttta ttagccagcc agcggcgttg ggttcgtgat
    17101 tagcgaagaa aaatcatcat aaattggtga aaaatataac aggtagttaa aaaccattag
    17161 tgctgagtaa attgccggat gacatcagaa cgatgccatc cgaacagtgg cttaaccctg
    17221 acggttgaaa cgttgccttt taacgtccag cgttagcgtt tcttctggtt gtatcgcata
    17281 cagtttctca ccctgctggc aaatccagcc aatccccagt tcacgggcga ttagggcgct
    17341 gtgggatacc ggacttccgg cgctaaggca gatacctttt acaaccgccg gatccagttg
    17401 cagtactgtg gaaggataaa tgttctccgc cagtagaata gttggcgagt taaactgcgg
    17461 gagttcttct ttcgtttggg tcaggtggac cagggtgcga tgcagaagat cgtccacatc
    17521 aatatagcga gcttgtagat attcatcatc cagttgctgg tattgctggc taagttcttt
    17581 aagaacttgc tgccaggcat attctgccgt gcaatgttca tgctgaagga gttcgcttgc
    17641 cgccgccagc agttccggat catctaacag tgtatggtga ccagaaaaga ttgcggcaat
    17701 atcgtcaagc ccgctggctt ctgcttttgc tgttaacgtc atcagatcta ataacgtgaa
    17761 gtcaatagcc tggcgtaatc gatcttgttc ttcttccacg gtcagggttg attttgcctg
    17821 taccgtacat aaaactggtt gataataaaa ggctttaccc gaaacaggcg gaacgggacg
    17881 cagagtaggt ggagcgactt cctccgtttc accaaagtta tcttcagcca gctgacggaa
    17941 agcgatcagt gcctcttcag cttctggccc tttcgcaatc aggcgcagcg tatcgttata
    18001 gcgaacttgt agtaacgcaa tctggttaat actctctggt gtgacgcatt tgccgttttt
    18061 ttccagcaac atatcggcat taaatgtcga taaggtataa accagccggg aggccggacg
    18121 tacatgcagg ccgttacggt tttttatgac caccgccaga gaacgggctt cttcatcgta
    18181 cgcaggacat gtgtcagaga ttttagtgtc ggaggacggt aaacccagtt gttcacgttt
    18241 ggcttccagc gcatgcatag cgtcaaagat aactttgtcg atatccgctc ccgaggccgc
    18301 gctgaccgtt gctgccagtg taccttcgac caacggcgca gcacacaaac gtacttttgc
    18361 ggcgatcttg ggagccagca attccagcgc agtttcagca ctcaataatg cgctacccat
    18421 atccatcatg accagcacat ggtcggcatc agcaacagat tcgatggcct ccatcacttt
    18481 gacggcatcg gtaccaatag gattttgtgg atcgtcaatt cccgcggcaa tggcgatttt
    18541 acaactatca ctcattaaca tctgacgggc taattcaccg acaccttctc ccagtcggct
    18601 gctatgtgaa actatgacca ggtttaccat caccaattcc ttactctttt gcggctaacg
    18661 ccaacatttg catcataaac atcaccgagg tcgcgccggg atcctggtga ccaatactgc
    18721 gttcaccgag ataactggcg cggcctttgc gggcttgcat cgtaatcgta ctttgtgcag
    18781 cggattcggc gattctactg gcagcttcga gcgccaccgg aacagagaga ttttgctcgc
    18841 tggactgacg taacgattcc accaccggca cccacacatc acacatggtt ttatcgccag
    18901 gttcggcttt cccgcgactg attacgccct ccacgccatc gcggaacatc tgataaagct
    18961 cttccagtgt caggctttgc cgtgcctggg tcgcctgtgc ggcgcggata aagaaggtac
    19021 cgaacagcgg accactggca ccaccgacgc tggaaagcag cgtcataccg gtattcttga
    19081 gaatgaaacc gatatcttta tctgcgatag cagggagttt ttccaccact ttgctaaagc
    19141 ctcggttcat atttagcccg tggtcagcgt cgccaatttc gcgatccagt ccggtaagat
    19201 actcgctctc ggtgctgaaa atatcgccac aacgagtgag ccagttaaca atttgagttc
    19261 tgctcagtga cattgctttc tccttattta ccccagttaa gggccggggt gtggaccggg
    19321 gcgtcccaga gtgccagcgt ttcgtcatca actttcagta aggtgattga gaaaccggtc
    19381 atatccagtg aggtgcagta cgcgccaatt aaattacgtt cgatagtcaa tcccgcttgc
    19441 tggcaacgtg tggtcaggcg gttatagacg ccgtacagct cagaaagcgg agttgcgcca
    19501 agattgttaa ccagcgcaat cacccgatcg ccagactgga gcggttgttt ggtttgttgt
    19561 tcttcctgcc aactgccttg ttgataatcc cagaaacgca aagtgcgatg gtatgagcca
    19621 ttttccagca gggtgtcgaa catttcatcg acggtttgat caagggaaga gaaggagcgg
    19681 cggtcaatac ccggctcacc atgaatgccg acgccaaact ccatctcatt atccgccagg
    19741 gtaaaagaag gtttgcccgc ggcaggaacg gtacaggcac cgagagcgat acctattgag
    19801 tggccttgat tattcaactt acgccccagt tccgcacagg cgtccagtga gtcgccacgc
    19861 tccgccgctg cgcctacgag tttttcaatt aatacggtgt tggcaacgcc gcgtcgcccg
    19921 gcagtataaa gactgtcttt taccgcaacg tcgtcatcaa tgaccacagt ggtcactttt
    19981 acgcggctat cgtgcagtaa ctcggtcgct gtttcaaagt taagaatatc gccggtgtaa
    20041 tttttgataa tcatcagtac accttcgccg ccatcaattt gcatggcgca ttcaaagatt
    20101 ttatcgggcg tcggtgaggt gaaaatttcg cccggacagg cccccgaaag catcccctga
    20161 ccgatataac cacagtgcat cggctcgtgt ccgctgccgc cacccgacag cagggcgact
    20221 tttcctgcaa cgggggcatc agctcgggtg acatacaccg gatcctgatg cagtgtcaga
    20281 gatggatgcg ctttcgccag tcctgccagt tgttcgtcca gtacgtcttg cacatcattg
    20341 atcaattttt tcattatttt gctccagcaa ttacggtagg gcatggatga tgttcaacga
    20401 cacggcgacc actgactgcc gatgaatcca ttgtgcatca ggcaagggaa aagaaaatta
    20461 gcccaaatta tgtttcatag tgaaacatat gctttaatga atgttccata ttgaaacttt
    20521 tacgtgtatt aatacttaaa attgcgagcc ggaacacctt ttgtcataag ggatgcggga
    20581 tatgagtggc gcttttaaca acgatggtcg gggcatatct cccttaattg caacctcctg
    20641 ggagcgatgc aataagctga tgaaacggga gacatggaac gtaccacatc aggcccaggg
    20701 cgtgacattt gcttctattt atcggcgtaa gaaagcgatg ctgacgctcg gtcaggctgc
    20761 gctggaagat gcctgggaat atatggcacc gcgagagtgt gcgctgctta tcctcgatga
    20821 aaccgcctgc attctcagcc gtaatggcga tccgcaaacc ttgcagcagc taagtgcact
    20881 gggattcaat gacggcacgt attgcgccga gggaattatt ggtacttgtg cgctatcgtt
    20941 agcggctatc tctggtcagg ccgtgaaaac gatggccgat caacatttca aacaggcact
    21001 ctggaactgg gccttttgtg caacgccgtt gtttgacagc aagggccgat tgacgggaac
    21061 aatagcgctg gcgtgtccgg ttgagcaaac taccgcagct gatttgccgt tgacgttggc
    21121 aatcgcccgc gaggtcggta atttactgct gacggacagt ttgctcgctg aaactaaccg
    21181 tcatttaaat caacttaatg ccctgttaga aagtatggat gatggcgtga ttagctggga
    21241 cgagcagggt aatttgcaat ttattaatgc ccaggcggcg cgggtcttgc gccttgacgc
    21301 gacggcaagt cagggacggg caatcactga actcttaacg ttacccgccg tattgcaaca
    21361 agcaataaaa caggcacatc cgctcaaaca cgtagaagca acctttgaaa gccagcacca
    21421 gtttattgat gcggtgataa cccttaaacc gataatagaa acgcagggaa ccagctttat
    21481 tttgttgctc catcctgtgg aacagatgcg gcagttgatg accagtcaat taggaaaagt
    21541 cagccatacc tttgctcata tgccacagga cgatccgcaa acccgccgct tgattcattt
    21601 tggtcgccag gcggcgcgca gtagctttcc tgtcctgctt tgtggagaag agggcgtggg
    21661 caaggcactg ctaagtcagg caattcataa tgaaagcgag cgtgctgcag gtccttatat
    21721 cgccgtcaat tgtgagttat atggtgatgc tgcgctggcg gaagaattta ttggtggcga
    21781 tcgcacggac aatgaaaatg gccgtctgag tcggctggaa ctggcacacg gcggcacgct
    21841 gtttcttgaa aagattgaat atctggcggt ggagttacag tctgctttgc ttcaggttat
    21901 caagcagggg gttatcacgc gactggatgc gcggcgttta ataccaattg atgtcaaagt
    21961 gattgcaaca acgaccgcgg acctcgcaat gctggtggaa caaaatcgtt ttagtcgcca
    22021 gctgtattac gcgctgcatg catttgaaat taccatcccg cctctgcgta tgcggcgtgg
    22081 cagcattccg gcgctggtga ataacaaatt acgcagtctt gaaaaacgct tctctacgcg
    22141 gctgaaaatt gatgacgatg ccctcgctcg cctggtttct tgtgcatggc caggcaacga
    22201 ttttgaactt tacagcgtca tcgagaatct tgctctgagt agtgataacg ggcgcattcg
    22261 cgtcagtgat ttacctgaac atctgtttac cgagcaggcg acagatgatg tcagcgccac
    22321 ccgcctttcc accagtctgt catttgcgga agttgaaaaa gaggcaatta ttaacgcagc
    22381 ccaggtcaca ggcggtcgca ttcaggaaat gtcggcttta cttgggatcg gccgcactac
    22441 gctgtggcgg aaaatgaagc aacatggcat tgatgcaggg cagtttaagc gccgggtatg
    22501 aaagacagaa acgatttctg atacatcaga gtgatctgta tttcattccg gcgcacgcta
    22561 acaattttca gcatcgttta agggcttgtc tatcccgcac ttaaaagctg aagcgatatc
    22621 ctccgttgac ttgcttctga tcaaagaggt taccctgcgt gtaatccgct tcgagataga
    22681 atgtgtgctg tttgttatac tgtgcactga ctcccacgcc gttattccag ccattacctt
    22741 tgaaactgta cttctcccgg gagttgttca cagatattcg gtatcccctg aaaactcgcg
    22801 gatagcgcca gtcttcacat agacattcag ctggctgttg cctgcggtga tgtcataccc
    22861 cagtatcatg ctggcacgcc ccagcagcga ttcgtagtga ttcagatgta tattgaggcc
    22921 attactcgcc ttcatagcca tctcattctg gtggctgtat gtaagctggg tttgcggctc
    22981 tatatagaac ccataaccag taggggacag gttgaacctc tgcccggctt ccagggagat
    23041 gctcattcca ttcgcagtgc cgttggcgtt aacgccgttg ttctgactgt ccagtacgtg
    23101 gaaactattt ttctggcgcg atgcttttat aacgagatcg ctgtaaaaac cgttttgtgc
    23161 catgtaactg gcgtacattc ccatgtagtc tgaacgtgcg gtaccgtcgc ctccgctata
    23221 gtccggcgat gcatgtgttg agccaatata cagaccgaca tacaacggca ttacatcaga
    23281 gagacgttta tccccaccaa actggatacc gctgtaaccc atgtcaaagc cgctcagttt
    23341 gccactggca aaggagtcca ggcttccccc ataactgcgc aaccagatat taccgtcttt
    23401 actctgattt cgcaggtcac ccatccgttg catcagcgta cggttttcaa catagttcaa
    23461 taagtaaccg acattgagat aattgccgcc agcatctgcg gtcgtggtgg gtttaggcgt
    23521 gggagcgggt tcaggcgtag gatcggggtt gactatggga ggctgagcgg gagctggtgt
    23581 gggttcagga ttaggagtcg gttccggaac tgtcccggaa gcgtaaagct cccagttagt
    23641 gccattttta cgcacatcgt acagatatcc ccccaactca acctgagaag acgcgctgaa
    23701 cgaggccgca ccgtcagtgg tttttaccac tgtcagaact tcatttcccg tagtggcctc
    23761 gctgccctgg ttgcggatag ccaatacgtg attaccagca ctacttccgc tgatattcaa
    23821 taaatcccct ttattattaa cgccattacc ctcgccaaca acatcagcac gcataataaa
    23881 ggtactgtta ccgctcaggt tctctacgtt taatgtggca aatgtgccgg cagttgaccc
    23941 gtggctggca aaatcgacag ttgaatggct cagcgccagc gtgtcgagat tagaattact
    24001 tgttacgttc cagacgctgt tattcattgc aacgtccagt ttcccgccat tgacattatc
    24061 gctgagggag gaacctgtcc aaaccgaccc tgggtgcata tctagattga ttagcccacc
    24121 tttggaaaga acgctaccgt tgataagcat acgacccgag gcgttgatgc ggctggcggc
    24181 ataaccatcg tcatgttgcg ttgcaatggc catctggtcg ggtgtactca tatcaatgac
    24241 cagatcgctc gtgaggtcga tctggctgtt ggtcatggca taaattcccc tggctcctgc
    24301 cgcgccggtg atagccaaac tgtctccggt tattctaccg ccgctgagcg cccacaaacc
    24361 cagcgccaga ctgccattac gatcaactgt aatatcggta ttttgcatgt tgacaacagc
    24421 cgttgccgtc tgggccgagg caccataaga accgccggaa aagatgctgt ttcgttgcgc
    24481 tgccgtgcca gaaaaattga ttgtcgcgtc tgaaccactg gtgacgaggc caccgccctg
    24541 cgcggaagaa atatggctat ctgcaccgat agtggttgta ccaccacgaa cttcgacgcc
    24601 attggccgcg gctccagtta catcaacagt gagtgcattc gcgctaacct ggccaaagct
    24661 ccagaggccg tgtgcattat cgccattggt tttaatggta ctgtttgttc cgagatcgac
    24721 aacagagttt ttctgtacgt ttatccccat ggcgctgtag ccctgaacat cgattgtcag
    24781 gtctgtcgcc gtaaaacgcg cagcaccatt ggcgttattg ccgttgagac caccgatata
    24841 aacacctgta cttccatcgg tcgtgatttt acttccgctt ccaagatcga cactggtgcc
    24901 atagtcattg atggttaggc ctataccgtt cgagttttca atggtgaatt gagtggctgt
    24961 tagtgttgag ctatgcccaa taatgatgcc gtcatcgtta ctcttaatgg tgctgcctgt
    25021 gcctaagtca gcatgggtat agtcaccaat taagttaatg ccgatggcag aggtttgacc
    25081 aacaacatct actgtgagtc ggttagctgt cagggagctg tttttgccct gaataatgat
    25141 tccttttgca tatccagagg cgtcgttgac attgacggtg acatcattac ccaggttgat
    25201 attgccaggc gtgtttcctg ctggggtcat tacaccatag aggtttcctg atggatcggc
    25261 ggtatctcct gtaattctgt caccatcatt aatagtaata ttggtgccat attgacttcc
    25321 tgtatcagca gctatcagca ggggggaaaa gataattgca ttcaaaccaa tagcgccaaa
    25381 ttttatcagt tgaattgagg gcgaacggat ttttaattca gcgagacgat ctgctttggt
    25441 attcccattg tgttgtttga tgcccatacc actcctatat agtacccaga ctatgggtct
    25501 atggattttg tcattttgtt taaatcaatg aataatatcc tcttatcatc atgatatttg
    25561 tatggtgcaa tcatgatgag cttctcagag aataattctc tattaccggg caaaatcagg
    25621 aacacaggaa ttaatatata tttaacatcc cccttacaaa ggtgggttta tatcgagtta
    25681 ttccctaagt tgtcgttgct tattccaatt cgttactata aatatggcaa aaatattaca
    25741 acaaacagcg gttaaaaaat ttggtgaaga ttttttgtaa taatcctaat tagttatggg
    25801 aatttcgctt gatgtatctg cataacaaaa acaatatgcg ccatttttgc attactaata
    25861 agaaaaagca aaaaacatcg atattcattt ttggtcaatg ggttttctgg cctatcgttg
    25921 ttattgtgct actggttatc attttcatct tgccaggatc gcacgtaatc acgttattcg
    25981 gggactttat ctgcgggata ttacccttca ggtaagtcct tttctcgcca gcatattgga
    26041 gcgtgatcaa tattgatcag ctgtgaaggg ggtgatgtgt agtggaccaa aacttacgtt
    26101 atatcactac taatgagata tccgtcatct gacactgatg tctttaatta ttctcgtggt
    26161 tcactgtagg caataagcac aaaagtgtag gatgttacaa gaatgattag gactcggtga
    26221 aatgaaaaat ccacgcaatt gcgtggatta tatatacttt tgcgctcttc atgagattta
    26281 gcgaaacctc atgagacaac aaattaatta gacgttgaaa aggaagttca tcacatcgcc
    26341 atctttaacg atgtaatctt taccttctgc acgcattttg cctgcttctt tcgcgccttg
    26401 ttcacctttg taagtgatga aatcttcaaa cgagatggtt tgtgcacgga taaagccttt
    26461 ttcaaaatca gtatggattt tgcccgctgc ctgcggcgcg gttgctccaa ccggaatggt
    26521 ccatgcacgc acttctttca ccccagcggt gaagtaagtt tgcaggttca gcagcttata
    26581 accggcacgg atcacacggt tcaggcccgg ctcttccagc ccaagctcct gcataaactc
    26641 gtcacgttct tcgtcgtcca gttcggcaat gtctgcttca acagcagcac aaaccggaac
    26701 cacaacagaa ccttctttcg ccgcgatttc acgcacctgg tcaagatatg ggttgttttc
    26761 aaaaccgtct tcgttgacgt tggcgatgta cattgttggt ttcagcgtca ggaagctcag
    26821 gtaacgaata gccgctttct cttcagcgct taaatccagc gcgcgcagca tacctgcatt
    26881 ttccaactgg ggcaggcatt tttccaggac cgccagctca gctttcgcgt ctttatcgcc
    26941 acctttggct ttcttctgta cgcgatgaat cgcacgttcg caggtgtcga ggtctgccag
    27001 cgccagttcg gtgttgataa cttcaatatc gtcagccggg ttaactttgc cggaaacgtg
    27061 aatgatgttg tcattttcaa agcagcgaac aacgtgaccg atcgcttcgg tttcacggat
    27121 gttggtcagg aactggttac ccagaccttc gcctttcgat gcgcctttta ccagaccggc
    27181 gatatcgaca aattccatgg tcgtgggaag cgtacgttgc ggttttacga tttcagccag
    27241 ttgatccagg cgagggtcag gcattggtac gacgcctgtg ttcggctcaa tggtgcagaa
    27301 tggaaagttg gccgcttcaa taccggcttt ggtcagcgcg ttgaacaggg tagatttccc
    27361 gacgttgggc aaaccgacga taccgcattt gaatcccatg atttaaatca ccttaatatc
    27421 ttaataatca acctgttatt gctaacagat tgcagaaatg gaaataactt tgcctattat
    27481 acacggcact cggcaaaaat gccgcagaca acgacttatt gcgctttaaa ggcgtgcaat
    27541 cggttcgttg ctttggtcaa gccatctgta aaccacattt cagtacaacg cgccgcttcg
    27601 tcgatggctt catcaattaa cttctgttca ctaacaggcg gtttgcctaa cacaaaaccg
    27661 acaactttat ttttatcgcc cggatgaccg attccgatgc gtaaacggtg aaagttaggg
    27721 ttattaccca atttactgat gatgtctttc agtccattgt gaccaccatg gccaccgccc
    27781 aatttaaatt tggcgacgcc aggaggcaga tccagttcgt cgtgggccac cagaatttcg
    27841 tccggattaa tgcggaaaaa actggccatc gccgcaacgg ctttgccgct gagattcata
    27901 aatgtagtcg ggactaacag gcggacatct tcgcctccaa gagtgactcg cgaagtataa
    27961 ccaaagaatt tagcctcttc gcgcagcgga gcgcgcaaac gctctgccag taagtcaacg
    28021 aaccaggcac cagcattatg tcgcgttgcg gcgtattcag caccggggtt cgccaggccg
    28081 acaatcaatt taatcgtcac gtttttttgt cctgagtgtg tacataactg gcgcgtagtt
    28141 tactggttgc ggccccgctt gacaaaaaac tgcgtatcaa atgcagataa cgtaataatt
    28201 gcatgagtgg actattagaa agtcaaggtg ttcaggcgtt tatttgtaaa gttttgttga
    28261 aataagggtt gtaattgtga tcacgcccgc acataaccca cagggtgttg tctatacttt
    28321 acacataagg aagaggggta ttccctgtta caacccagaa agttccggag gtgacatatg
    28381 aaacgcaaaa acgcttcgtt actcggtaac gtgctcatgg ggttgggtct ggtggtaatg
    28441 gtggtcggcg tggggtattc aatcctcaac cagttaccac agtttaatat gccccagtat
    28501 ttcgcacatg gtgcagtgct aagtattttc gtcggtgcca ttctctggct ggcgggtgcc
    28561 cgtgttggcg ggcatgaaca ggtgtgcgac cgttactggt gggttcgcca ctatgacaaa
    28621 cgttgccgcc gtagcgataa tcgccgtcat agctaacaaa taatgcagtt tgctgaccag
    28681 tcagtttgcg ctgactggtc aatctcgtac ttataaatcc gccatcgccg cgcgacgatt
    28741 cgggaagaac gccaggcgtc ccgggatcgg ttgaatgcca gcgcgagcca tagtgcgcag
    28801 tggctggaat tccacgttgc acacgcgcag ttcacatccc tcgggcagac gcttcacaaa
    28861 acgctggaac gcatcaagac caccagcatc aagtaccgga accgcatccc acttcagaat
    28921 cacaatccgt ttgccttcaa gacgtgactc caggtccgtg aacaagcctt cagcagcagc
    28981 aaaaaacagc gggccaataa cgcgcagaac caggacatcg tctggaacat ctacgactac
    29041 cggtgccagg cgagtcatac gtgcgatacg acgcataaac agcagcgatg ccagcacgat
    29101 ccccacgctg atggcaataa ccatatcaaa cagcacggtc agcgacatgc acagcagcat
    29161 gacaatgatg tcatctttcg gcgcatgacg cagcaagtcg accactttgt gcgcttcact
    29221 catgttccac gccaccatca acagcagggc agccatggcg gaaagcggca gccaggagag
    29281 cagcggtgcc agtaccagca gggcaagaat aaccagaata gagtggatca ccgccgagat
    29341 aggggaagtt gccccggcac ggacgttagc ggcagaacgc gcgatggcag ctgtagcggt
    29401 aatgccacca aagaacggag cgatgatatt ccccagtccc tgtccaacca gttcgctatt
    29461 cgccttgtgt ttcgtcccgg tcataccatc cagcaccacg gcgcagagca gagattcgat
    29521 tgcgccgagc attgccattg agaatgccgc aggcagcagt gtgcgaatag aatcccaggt
    29581 tagcgtgaat tctgaattag gcagatccca cggcagcacc agttgcggca gcagttgcgg
    29641 aataccgtta ccctgagaac catcggccag gacgtagtgg aattgcgaac cgatggtagc
    29701 aacatgtccg ccgagcaggt taacaatccc catcaccgcg caaccagcca gcaaggccgg
    29761 aaggtgaccg ggtaaacgaa tgcccagacg cggccaaaaa acaagaatac ctagcgtcac
    29821 aatgccaatg gcagcatcac ccacattaat ggtcggcagc gccataaata atgcgccgac
    29881 tttttgtaga taatgttccg ggacatgggc catttgcaga ccgagaaaat ctttaatctg
    29941 catggtaccg atggtgatcc cgatacccga ggtgaaacct aaggtgacgg aaaccggaat
    30001 atactcaatc aggcgaccaa agcgtgccag acccatcaga atcaaaaaaa tccccgacag
    30061 caaggtcgca accagcagtc ctgccagtcc aaactgttgc gacacgggat agagaattac
    30121 cacaaatgcc gcagtcggac cggaaacgct aaagcgtgac ccacccgtca gagcaatgac
    30181 aatccccgca acagctgcgg tatataaacc gtactggggt gccacaccac taccaatagc
    30241 caacgccatc gccagcggga tagcaataat cccgacggtt atcccggcaa tcaggtcacg
    30301 ggtaaaccgt gcggcagtat atttttcttt ccagcaagcg tcgatcagag cgcggaaagg
    30361 catcacatgt gaggaaaata ttttgttcac aataatgttt catccgtgag cgcatcatct
    30421 gtcaactaaa tggcaggtga aggaggcata ggtcatacaa atggatatta cagacaaaaa
    30481 aacccgccgc agcgggtctt tgagccgggt tcgattagtg ttcgaacatg gcagagatcg
    30541 attcttcgtt gctgatacga cgaatcgctt cggccagcat acctgacagg gtcagagtac
    30601 gcacgttcgg cagtgatttg atttcatcgc tcagcggaat ggtatcgcag acaacgactt
    30661 catcaattac agagttacgc aggttattcg ccgcgttgcc agagaagatc gggtgagtcg
    30721 cgtacgcaaa tacacgttta gcaccacgtt ctttcagagc ttcagcagct ttacacagcg
    30781 taccgccagt gtcgatcata tcatcgacca gtacgcagtc acgacctgca acgtcaccga
    30841 tgatatgcat cacctgggaa acgttcgcac gcggacgacg tttgtcgatg attgccatat
    30901 cggtatcgtt cagcagctta gcgatagcgc gggcacgcac aacgccgccg atgtccggag
    30961 aaaccacaat tgggttatcc agattcagct gcagcatgtc ttccagcagg atcgggctac
    31021 caaatacgtt atcaaccgga acgtcgaaga aaccctgaat ctgttcagcg tgcagatcca
    31081 ctgtcagcac acggtcaaca ccgacgctgg agaggaagtc tgcaaccact ttcgcagtga
    31141 ttggtacacg agcggaacgg acgcgacggt cctggcgcgc atagccaaag taggggataa
    31201 cagcggtgat acgacctgcg gaagcacgac gcagggcatc aaccataacg actaattcca
    31261 tcaggttgtc gttagtaggg gcacaagtgg actggatgat gaaaatatca ccaccgcgta
    31321 cattttcgtt gatttgtaca ctgacttcgc cgtcgctaaa gcgacctaca gcggcgtcgc
    31381 cgagtgaagt gtacaggcgg ttggcaatac gttgtgctag ttccggggtg gcgttaccag
    31441 caaaaagctt catatcaggc acgagaagaa cctcaggcat gcgtccattg gtggaaagaa
    31501 tctgccgaaa actgtgcggg ccaggcatga tcctttccag gcggtgtatt aaagagcgcg
    31561 atgcaacgtc tggaacaagg tgacgttgtc accgaaactc agcttgcccg gcttaaagca
    31621 tggctctgtg caatggggaa agattaacgc ctttcgccac aaagccattg agccattccg
    31681 gggcttgctc tagcacctgg cgggcttcag actctgtatc aaattcagca aagacacagg
    31741 cccctgtccc agtcaggcgc gacggggcgt attctaacag ccaggaaagc accgcatcaa
    31801 cctcgcgaaa acgttttctt gcgataacct cgcaatcatt gctgaattca cattttagca
    31861 acgtttctat tgaccttttt ggcgtattgc gcgggagttc aggatcttta aaaatcaccg
    31921 gagtcggaat acttacacca gggtgcgcca ccagatacca cttctctggc ggatccaccg
    31981 gcgttagtat ttcaccaacg ccttcggcaa acgcggcatg cccccgaaca aagacaggaa
    32041 catctgcgcc cagcgtcagc cccatttccg ccagctcatc catgcttagc ccgcattgcc
    32101 agagatgatt taatgccacc aggaccgtcg cggcattgga tgaaccaccg ccgagaccgc
    32161 cgcccatcgg caaacgcttg tcaatgctga tattcgcacc gcttcccgtc ggaagacgcc
    32221 cgctgtctgc cgcagttttt atcaacaatc gcgctgcgcg aacgatcagg ttatcttcat
    32281 gttccacgcc ttcaacgggc gttaacagac gaatatcccc atcgtcacga agctcaatgc
    32341 tgatggtgtc gccgtaatca agaaactgaa acagcgtttg cagcgtgtgg taaccatccg
    32401 cacgctgacc ggtaatgtat aaaaacagat taagttttgc cggagagggc cactgtgtcc
    32461 gcattatttc actatccagt tatccatttt taacttgatg cgttgaccac cgtcggtgag
    32521 ttccatattg gctggcatcg caggttgcgt tttggtgtca taaccaccat aaacaacctt
    32581 ccagtttttg ccattctggc tgtaggtaat ttcgctcagg cggtactggt cgtccagttt
    32641 gtagtcggtt gcatcacccg gtaaacctaa aatccactgg cgcaagctgt tgagcggaat
    32701 tggcattccg gtcaatttgc caatcatctc ttcggcgtca tcggcggtat aacgctgacc
    32761 tttattgtcg actaactgca cgttacccgg ttgagcattc agctccagtt ccgtgctgcc
    32821 caatgggtta gtgagcagca gacggtagcg atcctggccg gtttgctgcc agaaaaagcg
    32881 ggcgtacact ttttgttggt cagaaatata agcgaacgcg ccgcgagtct gatactgatt
    32941 aagattgcgc acgtcttgct gatgctgacg ccattgtggc gaatccgggc ttttgccagg
    33001 acctttgggc gtggtaacgg aacaggcagt gagcacaaga gcagccagcg gtagcaggcg
    33061 gataagacga aaatcgggca ggggcatagt gatgacaagt ccttgagata cgttgcagtt
    33121 ataaccctta atgctagcgt taccgtccgc tatcgtctat gttcaagttg tcttaattgc
    33181 cagaatctaa cggctttcgg caattactcc aaaagggggc gctctctttt attgatctta
    33241 cgcatcctgt atgatgcaag cagactaacc ctatcaacgt tggtattatt tcccgcagac
    33301 atgacccttt tagcactcgg tatcaaccat aaaacggcac ctgtatcgct gcgagaacgt
    33361 gtatcgtttt cgccggataa gctcgatcag gcgcttgaca gcctgcttgc gcagccgatg
    33421 gtgcagggcg gcgtggtgct gtcgacgtgc aaccgcacgg aactttatct tagcgttgaa
    33481 gagcaggata acctgcaaga ggcgttaatc cgctggcttt gcgattatca caatcttaat
    33541 gaagaagatc tgcgtaaaag cctctactgg catcaggata acgacgcggt tagccattta
    33601 atgcgtgttg ccagcggcct ggattcactg gttcttgggg agccgcagat cctcggtcag
    33661 gttaaaaaag cgtttgccga ttcgcaaaaa ggtcatatga aggccagcga actggaacgc
    33721 atgttccaga aatctttctc tgtcgcgaaa cgcgttcgca ctgaaacaga tatcggtgcc
    33781 agtgctgtgt ctgtcgcttt tgcggcttgt acgctggcgc ggcagatctt tgaatcgctc
    33841 tctacggtca cagtgttgct ggtaggcgcg ggcgaaacca tcgagctggt agcgcgtcat
    33901 ctgcgcgaac ataaagtaca gaagatgatt atcgccaacc gcactcgcga acgtgcccaa
    33961 attctggcag atgaagttgg cgcggaagtg attgccctga gtgagatcga cgaacgtctg
    34021 cgcgaagccg atatcatcat cagttccacc gccagcccgt taccgattat cgggaaaggc
    34081 atggtggagc gtgcattaaa aagccgtcgc aaccaaccaa tgctgttggt ggatattgcc
    34141 gttccgcgcg atgttgagcc ggaagttggc aaactggcga atgcttatct ttatagtgtg
    34201 gacgatctgc aaagcatcat ttcgcacaac ctggcgcagc gtaaagccgc agcggttgag
    34261 gcggaaacta ttgtcgctca ggaaaccagc gaatttatgg cgtggctgcg agcacaaagc
    34321 gccagcgaaa ccattcgcga gtatcgcagc caggcagagc acgttcgcga tgagttaacc
    34381 gccaaagcgt tagcggccct tgagcagggc ggcgacgcgc aagccattat gcaggatctg
    34441 gcatggaaac tgactaaccg cttgatccat gcgccaacga aatcacttca acaggccgcc
    34501 cgtgacgggg ataacgaacg cctgaatatt ctgcgcgaca gcctcgggct ggagtagcag
    34561 tacatcattt tcttttttta cagggtgcat ttacgcctat gaagccttct atcgttgcca
    34621 aactggaagc cctgcatgaa cgccatgaag aagttcaggc gttgctgggt gacgcgcaaa
    34681 ctatcgccga ccaggaacgt tttcgcgcat tatcacgcga atatgcgcag ttaagtgatg
    34741 tttcgcgctg ttttaccgac tggcaacagg ttcaggaaga tatcgaaacc gcacagatga
    34801 tgctcgatga tcctgaaatg cgtgagatgg cgcaggatga actgcgcgaa gctaaagaaa
    34861 aaagcgagca actggaacag caattacagg ttctgttact gccaaaagat cctgatgacg
    34921 aacgtaacgc cttcctcgaa gtccgagccg gaaccggcgg cgacgaagcg gcgctgttcg
    34981 caggcgatct gttccgtatg tacagccgtt acgccgaagc ccgccgctgg cgggtagaaa
    35041 tcatgagcgc cagcgagggt gaacatggtg gttataaaga gatcatcgcc aaaattagcg
    35101 gtgatggtgt gtatggtcgt ctgaaatttg aatctggcgg tcatcgcgtg cagcgtgttc
    35161 ctgctacgga atcgcagggt cgtattcata cttctgcttg taccgttgcg gtaatgccag
    35221 aactgcctga cgcagaactg ccggacatca acccagcaga tttacgcatt gatactttcc
    35281 gctcgtcagg ggcgggtggt cagcacgtta acaccaccga ttcggcaatt cgtattactc
    35341 acttgccgac cgggattgtt gttgaatgtc aggatgaacg ttcacaacat aaaaacaaag
    35401 cgaaggcgct ttcagtgctc ggtgctcgca tccacgctgc tgaaatggca aaacgccaac
    35461 aggccgaagc gtctacccgt cgtaacctgc tggggagtgg cgatcgcagc gaccgtaacc
    35521 gtacttacaa tttcccgcag gggcgcgtta ccgatcaccg catcaacctg acgctctacc
    35581 gcctggatga agtgatggaa ggtaagctgg atatgctgat tgaaccgatt atccaggaac
    35641 atcaggccga ccaactggcg gcgttgtccg agcaggaata atggaatatc aacactggtt
    35701 acgtgaagca ataagccaac ttcaggcgag cgaaagcccg cggcgtgatg ctgaaatcct
    35761 gctggagcat gttaccggca gagggcgtac ttttattctc gcctttggtg aaacgcatct
    35821 gactgacgaa caatgtcagc aacttgatgc gctactgaca cgtcgtcgcg atggtgaacc
    35881 cattgctcat ttaaccgggg tgcgagaatt ctggtcgttg ccgttatttg tttcgccagc
    35941 gaccttaatt ccgcgcccgg atacggagtg tctggtggag caggcactgg cgcggttgcc
    36001 tgaacaacct tgccgtattc ttgatctcgg gacgggtacc ggggcgattg cgcttgcgct
    36061 ggctagcgag cgcccggact gcgaaattat cgctgtagat cgtatgcctg atgctgtctc
    36121 cctggcacaa cgtaatgccc agcatctggc gatcaaaaat atccacattc tgcaaagcga
    36181 ctggtttagc gcgctagccg ggcagcagtt tgcgatgatt gtcagcaatc cgccgtatat
    36241 tgacgagcag gacccacatc ttcaacaagg cgatgtccgc tttgagccgc tcactgcgct
    36301 ggttgcggca gacagtggaa tggcagacat cgtgcatatc atcgaacagt cgcgtaacgc
    36361 gctggtatcc ggcggctttc tgcttctgga acatggctgg cagcagggcg aagcggtgcg
    36421 acaagcattt atcctcgcgg ggtatcatga cgtcgaaacc tgccgtgact atggtgataa
    36481 cgagcgcgta acgctcggcc gctattatca atgacaagtt tttctacact gcttagtgtt
    36541 catcttatta gtctcgcgct ttctgttggg ctattaacct tacgtttctg gctacgttat
    36601 cagaagcatc cacaggcatt tgctcgctgg acgcgcattg tgccgccggt tgtcgatacg
    36661 gtgttattgt taagcggcat tgcgttgatg gctaaagcgc acatcctgcc attttccggg
    36721 caggcacagt ggctgactga aaagctgttt ggagttatca tttatatcgt tttgggtttt
    36781 attgcactcg attatcgtcg tatgcacagt cagcaggcgc gcattattgc cttcccgctg
    36841 gcgttggtgg tgctgtacat catcattaaa ctcgccacca caaaagtacc gttactgggg
    36901 taagtcatga gatcgttagc tgatttcgaa tttaataaag cgccattgtg cgaaggcatg
    36961 atcctggctt gcgaagcaat ccgccgcgat tttccctcgc aagatgttta cgacgaactg
    37021 gagcgtctcg ttagtctggc gaaggaagaa atcagccagc ttctgccttt agaagagcag
    37081 ctggaaaaac tgatcgcgct gttttacggc gactggggat ttaaagcctc acgcggcgtt
    37141 tatcgtcttt ccgatgcatt atggctggac ctggtgttaa agaatcgaca gggcagtgcg
    37201 gtatcattag gtgcggtttt attatgggtc gcgaatcgtc tcgatttgcc gctgctgccg
    37261 gtgattttcc ctacgcagct gatattgcgc attgaatgtc cggatggcga aatttggctg
    37321 attaatcctt ttaacggtga atcgttaagc gaacatatgc tggacgtatg gttaaaggga
    37381 aatatcagcc cgtcggcgga actgttttat gaagaccttg atgaagctga taacattgag
    37441 gtaatccgca aattgctgga tacactcaaa gcctcgttga tggaagaaaa tcagatggag
    37501 ctggcgttac gcaccagcga agctttatta caattcaacc ctgaagatcc ctatgaaatt
    37561 cgcgatcgcg ggttgattta tgcgcaactg gattgcgaac acgttgcgtt gaacgattta
    37621 agttatttcg ttgaacagtg tccggaagac ccgatcagcg aaatgatccg tgcgcaaata
    37681 aataacatcg cgcataaaca tattgtgctg cattaattaa tcgacatttt actcaagatt
    37741 aaggcgatcc tatgaaacaa aaagtggtta gcattggcga catcaacgta gcaaatgacc
    37801 tgccgttcgt actgtttggc ggtatgaacg tgctggaatc tcgcgatctg gcgatgcgca
    37861 tttgcgagca ctacgtaact gtgacccaga aactgggtat cccttacgtg ttcaaagcct
    37921 cttttgacaa agccaaccgc tcctccatcc actcttatcg tggaccgggc ctggaagaag
    37981 ggatgaaaat cttccaggag ttgaagcaga cttttggcgt gaaaattatc accgacgttc
    38041 acgaaccaag tcaggcacag cccgttgctg atgtcgtgga tgtgattcag ttgccggcgt
    38101 ttcttgctcg ccagactgac ctggttgaag ccatggcgaa aaccggtgcg gtaattaacg
    38161 tcaagaaacc acagtttgtc agcccgggac agatgggtaa tatcgttgat aaattcaaag
    38221 aaggcggcaa cgaaaaagtg attctttgcg atcgtggtgc taacttcggc tatgacaacc
    38281 tggttgtcga tatgctgggc ttcagcatta tgaagaaagt gtctggtaac tcgccggtga
    38341 ttttcgacgt gacccacgca ctgcaatgcc gcgatccgtt tggcgcagct tccggtggtc
    38401 gtcgtgctca ggtggctgag ctggcacgag ccggtatggc ggtaggtctg gcggggctgt
    38461 ttattgaagc gcatccggat ccggaacatg cgaaatgtga tggtccatcc gcgctgccgc
    38521 tggctaaact ggaaccgttc ctcaagcaga tgaaagcgat tgatgatctg gtgaaaggtt
    38581 tcgaagaact ggataccagc aagtaatctt ttttgcttga aaaataaagt cttagcgttc
    38641 tgcgttaaga cttttttcat gggtgccaga tacaaaaaag gccgcaggct gttacccctg
    38701 cggccggttt cgggcgcata ttgccatcac ggcagcctga cgcccgtttt caccttactt
    38761 ccggttacgc caccagccga caatcgctgc ggtaataatt cccgccagga tcggtgctgc
    38821 caggtcgtgc cagaaaatca tggcaaactg cgcgagcgtc atatagccgc cttgttgtaa
    38881 tgacaacatt ttgcggctat tcttgaattg ttctggttca agattagccc ccgttctgtt
    38941 gtcaggttaa acctctcaac gtgcgggggt tttctctttc cagcaaccaa tgccaccagg
    39001 gataaagccc ccgcaacatt gcgcctcacc ggataacgcc ggcttgatgt ggatactacg
    39061 tctcaattca tcttcacttc atccctgaaa tgtttgcaat gaagagtgca ttccggtttt
    39121 tcaacagctg ttacagtcgt ttcatgagg
//
LOCUS       DAZUDJ010000045        38308 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.045, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000045 DAZUDJ010000000
VERSION     DAZUDJ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38308
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.045"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(26..1006)
                     /gene="ygfZ"
                     /locus_tag="ACHY1N_003044"
     CDS             complement(26..1006)
                     /gene="ygfZ"
                     /locus_tag="ACHY1N_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HFS4045323.1"
                     /translation="MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQ
                     VTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYA
                     VFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVKEGATTLLWFEHPAER
                     FLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRT
                     GTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE"
     gene            1249..1515
                     /gene="sdhE"
                     /locus_tag="ACHY1N_003045"
     CDS             1249..1515
                     /gene="sdhE"
                     /locus_tag="ACHY1N_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HFS4045324.1"
                     /translation="MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFI
                     RLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI"
     gene            1496..1903
                     /gene="ygfX"
                     /locus_tag="ACHY1N_003046"
     CDS             1496..1903
                     /gene="ygfX"
                     /locus_tag="ACHY1N_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HFS4045325.1"
                     /translation="MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLMPWPLSYTPLWMV
                     LLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQEWCIVKAPWMIKSGMMLRLRSD
                     GGKRQHLWLAADSMDEAEWRDLRRILLQQETQR"
     gene            complement(1943..2464)
                     /gene="fldB"
                     /locus_tag="ACHY1N_003047"
     CDS             complement(1943..2464)
                     /gene="fldB"
                     /locus_tag="ACHY1N_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HFS4045326.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLME
                     QYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALG
                     MLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSW
                     CEQILNEMAEHYA"
     gene            2576..3472
                     /gene="xerD"
                     /locus_tag="ACHY1N_003048"
     CDS             2576..3472
                     /gene="xerD"
                     /locus_tag="ACHY1N_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFS4045327.1"
                     /translation="MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRG
                     LTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            3497..4207
                     /gene="dsbC"
                     /locus_tag="ACHY1N_003049"
     CDS             3497..4207
                     /gene="dsbC"
                     /locus_tag="ACHY1N_003049"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HFS4045328.1"
                     /translation="MKKGFMLFTLLAAFSGFAQADDAAIQQTLAKMGIKSSDIQPAPV
                     AGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALEKEMIVYK
                     APQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLDSDAEKEMKAIW
                     CAKDKNKAFDDVMAGKSAAPASCDVDIADHYALGVQLGVSGTPAVVLSNGTLVPGYQP
                     PKEMKEFLDEHQKMTSGK"
     gene            4213..5946
                     /gene="recJ"
                     /locus_tag="ACHY1N_003050"
     CDS             4213..5946
                     /gene="recJ"
                     /locus_tag="ACHY1N_003050"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFS4045329.1"
                     /translation="MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELERS
                     VKGMLPWQQLSGVEKAVEILYNAFREGTRIIVVGDFDADGATSTALSVLAMRSLGCSN
                     IDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVVHARSLGIPVIVTD
                     HHLPGETLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERGIA
                     IPNLAELLDLVALGTVADVVPLDANNRILTWQGMSRIRAGKCRPGIKALLEVANRDAQ
                     KLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLANELDALNQTRKEIEQ
                     GMQVEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPGMMLKFGGHAMAAGLSLEEDKFELFQQRFG
                     ELVTEWLDPSLLQGEVVSDGPLSPAEMTMEVAQLLRDAGPWGQMFPEPLFDGHFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINEFRGNRS
                     LQIIIDNIWPI"
     gene            6037..7135
                     /gene="prfB"
                     /locus_tag="ACHY1N_003051"
     CDS             join(6037..6111,6113..7135)
                     /gene="prfB"
                     /locus_tag="ACHY1N_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFS4045330.1"
                     /translation="MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAE
                     LDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRG
                     FKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            7145..8662
                     /gene="lysS"
                     /locus_tag="ACHY1N_003052"
     CDS             7145..8662
                     /gene="lysS"
                     /locus_tag="ACHY1N_003052"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFS4045331.1"
                     /translation="MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDH
                     TSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGA
                     AARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITE
                     YPAEVSPLARRNDINPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(8705..9253)
                     /gene="idi"
                     /locus_tag="ACHY1N_003053"
     CDS             complement(8705..9253)
                     /gene="idi"
                     /locus_tag="ACHY1N_003053"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFS4045332.1"
                     /translation="MQTEHVILLNAQGVPTGTLEKYAAHTADTRLHLAFSSWLFNAKG
                     QLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDF
                     RYRATDPNGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSP
                     WMVMQAANSEARKLLSAFAQHN"
     gene            9308..9379
                     /locus_tag="ACHY1N_003054"
     CDS             9308..9379
                     /locus_tag="ACHY1N_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045333.1"
                     /translation="MINQVSVYRQPPVLSGCRQVKTI"
     gene            complement(9376..9501)
                     /gene="yqfG"
                     /locus_tag="ACHY1N_003055"
     CDS             complement(9376..9501)
                     /gene="yqfG"
                     /locus_tag="ACHY1N_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YqfG"
                     /protein_id="HFS4045334.1"
                     /translation="MNFLMRAIFSLLLLFTLSIPVISDCVAMAIESRFKYMMLLF"
     gene            complement(9503..10951)
                     /gene="uacT"
                     /locus_tag="ACHY1N_003056"
     CDS             complement(9503..10951)
                     /gene="uacT"
                     /locus_tag="ACHY1N_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urate/proton symporter UacT"
                     /protein_id="HFS4045335.1"
                     /translation="MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAG
                     AVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFA
                     AVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGL
                     SIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFG
                     FLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFL
                     ALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVC
                     ISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYN
                     LYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHAD
                     LVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE"
     gene            11387..13306
                     /gene="ygfT"
                     /locus_tag="ACHY1N_003057"
     CDS             11387..13306
                     /gene="ygfT"
                     /locus_tag="ACHY1N_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     YgfT"
                     /protein_id="HFS4045336.1"
                     /translation="MNKFIAAEAAECIGCHACEIACAVAHNQENWPLSHSDFRPRIHV
                     VGKGQAANPVACHHCNNAPCVTACPVNALTFQSDSVQLDEQKCIGCKRCAIACPFGVV
                     EMVDTIAQKCDLCNQRSSGTQACIEVCPTQALRLMDDKGLQWIKVARQRKTAAGKASS
                     DAQPSRSAALLPVNSRKGADKISASERKTHFGEIYCGLDPLQATYESDRCVYCAEKAN
                     CNWHCPLHNAIPDYIRLVQEGKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKD
                     HSGAVSIGNLERYITDTALAMGWRPDVSKVVPRSEKVAVIGAGPAGLGCADILARAGV
                     QVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDITFSDL
                     TSEYDAVFIGVGTYGMMRADLPHEDAPGVIQALPFLTAHTRQLMGLPESEEYPLTDVE
                     GKRVVVLGGGDTTMDCLRTSIRLNAASVTCAYRRDEVSMPGSRKEVVNAREEGVEFQF
                     NVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADVLIMAFGFQ
                     AHAMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGR
                     QAARDMLTLFDTKAS"
     gene            13306..13794
                     /gene="ygfS"
                     /locus_tag="ACHY1N_003058"
     CDS             13306..13794
                     /gene="ygfS"
                     /locus_tag="ACHY1N_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417362.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HFS4045337.1"
                     /translation="MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADVFLPRLKVQ
                     RLDSISAPVMCHQCENAPCVGACPVGALTMGEQVVQTNSARCIGCQSCVSACPFGMIT
                     IQSLPGDTRQQIVKCDLCEQREEGPACVESCPTQALQLLTERELRRVRQQRIVASGEN
                     PL"
     gene            complement(13830..15197)
                     /gene="ghxQ"
                     /locus_tag="ACHY1N_003059"
                     /gene_synonym="ygfQ"
     CDS             complement(13830..15197)
                     /gene="ghxQ"
                     /locus_tag="ACHY1N_003059"
                     /gene_synonym="ygfQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxQ"
                     /protein_id="HFS4045338.1"
                     /translation="MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLA
                     MVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCAISLTAFTA
                     FSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
                     LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIA
                     ISIIGLIFDPAVKYHGLVAMPSLTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVF
                     DATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTA
                     AGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFI
                     DAMAGLVCAVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYA
                     GGWAI"
     gene            complement(15233..16549)
                     /gene="guaD"
                     /locus_tag="ACHY1N_003060"
     CDS             complement(15233..16549)
                     /gene="guaD"
                     /locus_tag="ACHY1N_003060"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008892 - guanine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006147 - guanine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HFS4045339.1"
                     /translation="MSGEHTLKAVRGSFIDVTRTVDNPEEIASALRFIEDGLLLIKQG
                     KVEWFGEWEDGKHQIPDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLN
                     KHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINM
                     RMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQM
                     AMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHC
                     VHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFN
                     MLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEP
                     TATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN"
     gene            complement(16567..17967)
                     /gene="xanQ"
                     /locus_tag="ACHY1N_003061"
     CDS             complement(16567..17967)
                     /gene="xanQ"
                     /locus_tag="ACHY1N_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanQ"
                     /protein_id="HFS4045340.1"
                     /translation="MSDINNAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPAL
                     IVGAALQLSAETTAYLVSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIA
                     LGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGL
                     SLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGL
                     CVGYIASLCLGMVDFSSMRNLPLITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGD
                     ITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGV
                     ASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGL
                     KRRETLIVATSLGLGLGVSYDPEIFKILPASIYVLVENPICAGGLTAILLNIILPGGY
                     RQENVLPGITSAEEMD"
     gene            complement(18132..21002)
                     /gene="xdhD"
                     /locus_tag="ACHY1N_003062"
     CDS             complement(18132..21002)
                     /gene="xdhD"
                     /locus_tag="ACHY1N_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     Mo/Fe-S-binding subunit"
                     /protein_id="HFS4045341.1"
                     /translation="MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFA
                     GSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYND
                     PAAALIITDLLDRIAAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATID
                     IAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHL
                     DVSKAEALPGVVHVITHLNCPDIYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVV
                     AESEEIALEALKLIDVEYEVLKPVMSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNS
                     HAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCP
                     TETHICFTRMDGDRLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQD
                     ILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDF
                     RANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNF
                     AITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEI
                     LRQGREMIQWSSPKPQNSDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSG
                     GADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARL
                     AAENLREKILFHGAQMLGEAVADVQLATPGVVRGKKGEVSFGDIAHKGETGTGFGSLV
                     GTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGAT
                     LRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLVPSDDKVGPFGAKS
                     ISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI"
     gene            complement(20999..21778)
                     /gene="ygfM"
                     /locus_tag="ACHY1N_003063"
     CDS             complement(20999..21778)
                     /gene="ygfM"
                     /locus_tag="ACHY1N_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     FAD-binding subunit"
                     /protein_id="HFS4045342.1"
                     /translation="MIEQFFRPDSVEQALELKRRYQDEAVWFAGGSKLNATPTRTDKK
                     IAISLQDLELDWVDWDNGALRIGAMSRLQPLRDARFIPAALREALGFVYSRHVRNQST
                     IGGEIAARQEESVLLPVLLALDAELVFGNGETLSIEDYLACPCDRLLTEIIIKDPYRT
                     CATRKISRSQAGLTVVTAAVAMTDHDGMRIALDGVASKALRLHDVEKQNLEGNALEQA
                     VANAIFPQEDLRGSVAYKRYITGVLVADLYADCQQAGEEAV"
     gene            complement(21829..23157)
                     /gene="ssnA"
                     /locus_tag="ACHY1N_003064"
     CDS             complement(21829..23157)
                     /gene="ssnA"
                     /locus_tag="ACHY1N_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HFS4045343.1"
                     /translation="MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDA
                     SYKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPDFISTLKNLWWRLDRALDEES
                     LYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRDAFLKVGLRAMTCFETTDRN
                     NGIKELQEGVEENIRFARQIDEAKKAATEPYLVEAHIGAHAPFTVPDAGLEMLHEAVK
                     ATGRGLHIHAAEDLYDVSYSHHWYGKDLLARLAQFDLIDSKTLVAHGLYLSKDDIALL
                     NQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFEEMKFAFFKHRDAGG
                     PLWPDSFAKALTNGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIA
                     FGMGSGSVHSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA"
     gene            complement(23160..26258)
                     /gene="ygfK"
                     /locus_tag="ACHY1N_003065"
     CDS             complement(23160..26258)
                     /gene="ygfK"
                     /locus_tag="ACHY1N_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenate reductase subunit YgfK"
                     /protein_id="HFS4045344.1"
                     /translation="MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKGKTV
                     SVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFIELKTVQILDRLELEKPCIDAED
                     ECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQ
                     PPMQQFIDNMMDASDHPKFAQYRDTLNKLLQDDAFLARHGLQEKRESLQALPARIPTS
                     MVQGVTLSTMHGCPPHEIEAICRYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGY
                     IGLKEESFDHDLKLTQALEMLERLMALAKEKSLGFGVKLTNTLGTINNKGALPGEEMY
                     MSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKP
                     GGYLRLSACMRELEGSDAWGLDHVDVERLNRLAADALTMEYTQKHWKPEERIEVAEDL
                     PLTDCYVAPCVTACAIKQDIPEYIRLLGEHRYADALELIYQRNALPAITGHICDHQCQ
                     YNCTRLDYDSALNIRELKKVALEKGWDEYKQRWHKPAGSGSRHPVAVIGAGPAGLAAG
                     YFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVADHGVKFEYGCSPD
                     LTVEQLKNQGFHYVLIATGTDKNSGVKLAGDNQNVWKSLPFLREYNKGTALKLGKHVV
                     VVGAGNTAMDCARAALRVPGVEKATIVYRRSLQEMPAWREEYEEALHDGVEFRFLNNP
                     ERFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLHVDSLITAIGEQQDTEALNAMG
                     VPLDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDAILSRENIRSH
                     QNDKYWNNVNPAEIYQRKGDISITLVNSDDRDAFVAQEAARCLECNYVCSKCVDVCPN
                     RANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKITVFSLAQDFDNSS
                     NPGFLVEDCRVRVRLNNQSWVLNIDSEGQFNNVPPELNDMCRIISHVHQHHHYLLGRV
                     EV"
     gene            complement(26580..27158)
                     /gene="mocA"
                     /locus_tag="ACHY1N_003066"
     CDS             complement(26580..27158)
                     /gene="mocA"
                     /locus_tag="ACHY1N_003066"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070567 - cytidylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032324 - molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HFS4045345.1"
                     /translation="MSAIDCIITAAGLSSRMGQWKMMLPWQQGTILDTSIKNALQFCS
                     RIILVTGYRGNELHERYANQSNITIIHNPDYAQGLLTSVKAAVPAVQTEHCFLTHGDM
                     PTLTIDIFRKIWSLRNDGAILPLHNGIPGHPILVSKPCLMQAIQRPNVTNMRQALLMG
                     AHYSVEIENAEIILDIDTPDDFITAQKRYTKI"
     gene            27261..28031
                     /gene="yqeC"
                     /locus_tag="ACHY1N_003067"
     CDS             27261..28031
                     /gene="yqeC"
                     /locus_tag="ACHY1N_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium cofactor biosynthesis protein YqeC"
                     /protein_id="HFS4045346.1"
                     /translation="MKSIVDPSALVIDLGAQKRPTVISVVGAGGKTSLLFWLAELLQA
                     SGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASLTSPISFCFHSWKANQGKVQGFT
                     PEAIDALVQRPECDVILIEADGSRGMPLKAPDEHEPCIPKSSCCVIAVMGGHTLGAKV
                     STENVHRWSQFADITGLTPDATLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQC
                     ENAIAQSELLQPLQQHDVEAIWLGDIQEHPAIARRFVN"
     gene            28079..29704
                     /gene="yqeB"
                     /locus_tag="ACHY1N_003068"
     CDS             28079..29704
                     /gene="yqeB"
                     /locus_tag="ACHY1N_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent molybdenum cofactor
                     biosynthesis protein YqeB"
                     /protein_id="HFS4045347.1"
                     /translation="MNIFTEAAKLEEQNCPFAMAQIVDSRGSTPRHSAQMLVRADGSI
                     VGTIGGGMVERKVIEESLQALQERKPRLFHGRMARNGADAVGSDCGGAMSVFISVHGM
                     RPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLHAESFGAAV
                     EALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLRQLREKGVAEE
                     HIARLHAPVGYNIGAETPQEIAISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGA
                     GDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEMTVEGVTARLATSSA
                     EAMKLTERGFIPVMVDPACSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFT
                     AGKDCHAVIETNRGHWLGQVIYSGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVK
                     LGDLVKEGDVIAWIGEHEIKAPLTGMVRGLLNDGLAVVGGFKIGDIDPRGETADFSSV
                     SDKARAIGGGVLEALMMLMHQGVKATKEVLEVA"
     gene            complement(29745..30677)
                     /gene="arcC"
                     /locus_tag="ACHY1N_003069"
     CDS             complement(29745..30677)
                     /gene="arcC"
                     /locus_tag="ACHY1N_003069"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFS4045348.1"
                     /translation="MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIV
                     THGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGI
                     NKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVV
                     ASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLA
                     EMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAA
                     ASFARSRAGREALITVLSKAKEGIEGKTGTVICQ"
     gene            complement(30725..32110)
                     /gene="hyuA"
                     /locus_tag="ACHY1N_003070"
     CDS             complement(30725..32110)
                     /gene="hyuA"
                     /locus_tag="ACHY1N_003070"
                     /EC_number="3.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311773.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-phenylhydantoinase"
                     /protein_id="HFS4045349.1"
                     /translation="MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEI
                     DATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCR
                     LRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKL
                     NDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAE
                     AIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYD
                     TEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCP
                     NGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVV
                     IIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRF
                     LRRKPFVPPVL"
     gene            complement(32163..33374)
                     /gene="ygeY"
                     /locus_tag="ACHY1N_003071"
     CDS             complement(32163..33374)
                     /gene="ygeY"
                     /locus_tag="ACHY1N_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HFS4045350.1"
                     /translation="MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHR
                     IKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDAHIDTVGIGNIKNWDFDPYEGME
                     TDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYII
                     EQSGIRPEFVVSTEPTDCQVYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPIL
                     GELQELSQRLGYDEFLGKGTLTVSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGAL
                     DEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEEDHFTVKALVNAYEG
                     LFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMY
                     AAIPLSWLATE"
     gene            complement(33432..34628)
                     /gene="dpaL"
                     /locus_tag="ACHY1N_003072"
     CDS             complement(33432..34628)
                     /gene="dpaL"
                     /locus_tag="ACHY1N_003072"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008838 - diaminopropionate ammonia-lyase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HFS4045351.1"
                     /translation="MSVFSLKIDIADNKFFNGETSSLFSQSQAKLARQFHQKIAGYRP
                     TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSF
                     EHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAE
                     CIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMR
                     EMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIV
                     NVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRI
                     ISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEG
                     KHAVAP"
     gene            complement(34686..35873)
                     /gene="ygeW"
                     /locus_tag="ACHY1N_003073"
     CDS             complement(34686..35873)
                     /gene="ygeW"
                     /locus_tag="ACHY1N_003073"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="knotted carbamoyltransferase YgeW"
                     /protein_id="HFS4045352.1"
                     /translation="MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAAL
                     KALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE
                     TVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC
                     DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFG
                     MDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKV
                     MEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADI
                     SGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQE
                     RVK"
     gene            36352..38124
                     /gene="ygeV"
                     /locus_tag="ACHY1N_003074"
     CDS             36352..38124
                     /gene="ygeV"
                     /locus_tag="ACHY1N_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4045353.1"
                     /translation="MELATTQSVLMQIQPTIQRFARMLASVLQVEIVDENLCRVAGTG
                     AYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTPVI
                     LQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISKIF
                     ATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGH
                     MQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRV
                     MRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPEQL
                     LESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREI
                     LPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIE
                     LLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGEVI
                     DSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREALSRHNSKKQ
                     VADELGIGIATLYRKIKKYELLNT"
     gene            complement(38164..>38308)
                     /locus_tag="ACHY1N_003075"
     CDS             complement(38164..>38308)
                     /locus_tag="ACHY1N_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HFS4045354.1"
                     /translation="ATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCE
                     KTK"
BASE COUNT         9419 a         9507 c         9986 g         9396 t
ORIGIN      
        1 taaatgcctg atgcgataaa gagatttact cttcgagcga atacggcagc ggctcgatat
       61 gcagtgtatt cgcatcgtcg cgtacgcgga agatgctatc cggttccata tcgttattca
      121 tgacgacctg taccacgacc tgaccatctt ccagttttac cgcagccagc accgtaccgg
      181 tacgacgcca gttctcgccc attttcagct ctaagtcttc accagcttcc ggcagtcggc
      241 tggcgctacc tgccagcaac cagagcgcac gtttattggc accacggaat tttgctcgcg
      301 ccaccatctc ttgtccggta tagcagcctt ttttaaagct gatgccgccc agcgcctgga
      361 ggttggtcgc ctgtgggata aactgcccgc tgttggcggc atcaatcacc gggaaacccg
      421 cttcaatgtt taatgccagc cactgttggc tattgttcag ttccgcttca ccgcgcagtt
      481 tatcggtcag catattagca gtagcttcat cggttacgat caggaaacgt tctgccgggt
      541 gttcaaacca tagcaaagtg gtcgcgcctt ctttaactac ctgtttttct ttcgaaggca
      601 gttcactaaa gagatttgcc agcgcggcgc gcgcctgaaa accggcaaca ccaagcagca
      661 cacgctcgtc gtctggcgcg atggtcactt tagagaatac cgcatatttt ttcagttcag
      721 tcagctgcgg ttcacgcacg ctgcgccgtt caatccatgc aaagccatcg ccgtcgcgga
      781 acagacgtaa attgctccac attttacctt tggcgtcgca atgggcggcg agcaggtgct
      841 gatcttctgc catctggctg acatctgctg tcacctgacc ctgcatatat ttttcgctgt
      901 ccgcgccagt aatggtggca agcgcccagt catcaagcgt catcagcgtc agcggtaaac
      961 gggcagaagc cgtaggctga cggggaggaa aaggtgtaaa agccataata gagtcctgag
     1021 ttgcttaacg gcgtattaat gactaatggt aaaagagcta tgaggcaatg caagtgcttt
     1081 cactacgcga tctgtgcctt ctgcgaggcg acttccaaaa aaatgaagcc attgaattgt
     1141 tgtgaattaa tttcgcgatc gcgatggtgt ttactgatat tcccgtaaaa gaaggcgaaa
     1201 aacacgttac aatagccggg tactggattt tcgtgagaca ggaagaagat ggacattaac
     1261 aacaaagccc gcattcattg ggcatgccgc cgtggtatgc gcgaactcga tatttcaatc
     1321 atgccgtttt tcgaacatga gtacgacagc ttaagcgatg acgaaaaacg catctttatt
     1381 cgtctgctgg aatgtgacga tccggacctg tttaactggc tgatgaatca cggtaaaccg
     1441 gccgatgcag aactggaaat gatggtccga ctcatccaga cacggaaccg ggaacgtggt
     1501 cctgtggcaa tctgatttgc gcgtctcctg gcgcgcacag tggctttcct tgctgattca
     1561 tgggctggtt gccgctgtta ttttactcat gccctggcca ctcagttaca ccccgttatg
     1621 gatggtgtta ctttcgctgg tggtgtttga ttgcgttcgc agccagcggc gtattaatgc
     1681 tcgccagggg gaaattcgct tgttgatgga cgggcgtttg cgttggcaag ggcaggagtg
     1741 gtgcatcgtc aaagcaccgt ggatgattaa gagcggcatg atgctgcgtt tacgttctga
     1801 tggcggtaaa cggcaacatt tatggctggc agccgacagc atggacgaag ccgaatggcg
     1861 ggatttacgg cggattttgt tgcaacaaga gacgcaaaga taaagatgac ggcaaagcat
     1921 atgcgctaag ccgtcagtga gatcaggcgt aatgctctgc catttcgttg aggatttgct
     1981 cgcaccagct ctgaatacgc tcgtcgctaa ggtcatactg gttagtttca tccagcgcca
     2041 gacccacgaa cagttgcccg tcagcaatca ccggtttcgg gctggtaaat tcatatcctt
     2101 ccgttggcca gtagccgacg aacttcacgc ctttggtcga gagtttgtca tgcagcatac
     2161 cgagcgcatc gaggaaccac tcgccgtatc ccagttgatc gccaagccca tacagcgcaa
     2221 caattttacc ttcaaggttc aggtcgtcga gctgatccca gacggcttcc cagtcttcct
     2281 ggatttcacc aaaatcccag gtcgggatac ccagaatgag cacatcgtac tgctccatta
     2341 atttcgggga gtcgtccttg aggttatgta aggtcaccag ttctgggccg ataatatcgc
     2401 ggattttttc tgccgccatt tcggtgtaac aggtgctgga accgtaaaaa agacccatat
     2461 tcataacgta agcttctcga ttctgctgtg gcttttgcag ctagtgtatc agaatcgctt
     2521 tagtcacggc acaataaggc ataatggatc aaatgagtga ccataagggg cgcaagtgaa
     2581 acaggatctg gcacgcatcg agcagtttct tgatgctctg tggctggaaa aaaatctggc
     2641 tgaaaatacg ttgaacgctt accgtcgcga tctgtcaatg atggtggagt ggttgcatca
     2701 ccgcgggttg acgctggcga cggcgcaaag tgacgatttg caggcattac tggcagaacg
     2761 gctggagggc gggtataaag ccaccagctc agcgcgtttg ctgagtgcag tgcgccgatt
     2821 gttccagtat ctttatcgcg aaaagtttcg tgaagacgat cccagtgcgc atctcgcttc
     2881 accgaaattg ccccagcgtt tgccaaaaga tttaagcgaa gcgcaggtcg aacgtttatt
     2941 acaggcacca ttaattgatc agccactgga gctacgcgat aaagccatgc ttgaagtgtt
     3001 gtatgctacc gggctgcgtg tctctgaact ggtcggactg acaatgagtg atatcagcct
     3061 gcgtcagggc gtagtgcggg tcattggtaa aggcaacaaa gagcgcctgg taccgttagg
     3121 tgaagaggcg gtttactggc tggaaaccta tctggaacat gggcgtccgt ggctgctgaa
     3181 tggtgtgtca attgacgtgt tgtttcccag ccagcgtgcg cagcagatga cgcgacagac
     3241 cttctggcac cgcattaaac attatgctgt gctggcgggt atcgacagcg aaaagctgtc
     3301 accgcatgta ttgcgtcacg cttttgccac ccatttatta aatcatggtg cggatttacg
     3361 cgtggtgcag atgctactgg gccacagcga cctctccacc acgcaaattt atacgcatgt
     3421 cgctaccgag cgtctgcggc aacttcatca acagcatcac ccgcgggcgt gatgtctgaa
     3481 aagaacggga agatttatga agaaaggttt tatgttgttt actttgttag cggcgttttc
     3541 aggttttgct caggctgatg acgcggcaat tcaacaaacg ttagccaaaa tgggcatcaa
     3601 aagcagcgat attcagcccg cgcccgtagc tggcatgaag acagttctga ctaacagcgg
     3661 cgtgttgtac atcaccgatg atggtaaaca tatcattcag gggccaatgt atgacgttag
     3721 cggcacggct ccggtcaatg tcaccaataa gatgctgtta aagcagttga atgcgcttga
     3781 aaaagagatg atcgtttata aagcgccgca ggaaaaacac gtcatcaccg tgtttactga
     3841 tattacctgt ggttactgcc acaaactgca tgagcaaatg gcagactata acgcgctggg
     3901 gatcaccgtg cgttatcttg ctttcccgcg ccaggggctg gacagcgatg cagagaaaga
     3961 aatgaaagct atctggtgtg cgaaagataa aaacaaagcg tttgatgatg tgatggcagg
     4021 taaaagtgcc gcaccagcca gctgcgacgt ggatattgcc gaccattacg cacttggcgt
     4081 ccagcttggc gttagcggta ctccggcagt tgtgctgagc aatggcacac ttgttccggg
     4141 ttaccagccg ccgaaagaga tgaaagaatt cctcgacgaa caccaaaaaa tgaccagcgg
     4201 taaataattc gcgtgaaaca acagatacaa cttcgtcgcc gtgaagtcga tgaaacggca
     4261 gacttgcccg ctgaattgcc tcccttgctg cgccgtttat acgccagccg gggcgtgcgc
     4321 agtgcgcaag aactggaacg cagtgttaaa ggtatgttgc cctggcagca actgagcggt
     4381 gtcgaaaagg ccgttgagat cctttacaac gcttttcgcg aaggaacgcg gattattgtg
     4441 gtcggtgatt tcgacgccga cggcgcgacc agcacggctc taagcgtgct ggcgatgcgc
     4501 tcgcttggtt gcagcaatat cgactacctg gtaccaaacc gtttcgaaga cggttacggc
     4561 ttaagcccgg aagtggtcga tcaggcccat gcccgtggcg cgcagttaat tgtcacggtg
     4621 gataacggta tttcctccca tgcgggggtt gtacacgctc gctcgttggg cattccggtt
     4681 attgttaccg atcaccattt gccgggcgaa acattacccg cagcggaagc gatcattaac
     4741 cctaacttgc gcgactgtaa tttcccgtcg aaatcactgg caggcgtggg tgtggcgttt
     4801 tatctgatgc tggcgctgcg cacctttttg cgcgatcagg gctggtttga tgagcgtggc
     4861 atcgcaattc ctaacctggc agaactgctg gatctggtcg cgctgggaac agtggcggac
     4921 gtcgtgccgc tggacgctaa taatcgcatt ctgacctggc aggggatgag tcgcatccgt
     4981 gccggaaagt gccgtccagg gattaaagcg ctgctggaag tggcaaaccg tgatgcacaa
     5041 aaactcgccg ccagcgattt aggttttgcg ctggggccac gtctcaatgc tgccggacga
     5101 ctggacgata tgtccgtcgg tgtggcgctc ttgctgtgcg acaacatcgg cgaagcgcgc
     5161 gtgctggcaa atgaactcga tgcgctaaac cagacgcgaa aagagatcga acaaggaatg
     5221 caagttgaag ccctgaccct gtgcgagaaa ctggagcgaa gtcgcgacac gctacccggc
     5281 gggctggcaa tgtatcaccc cgaatggcat cagggcgttg tcggtattct ggcttcgcgc
     5341 atcaaagagc gttttcaccg tccggttatc gcctttgcgc cagcaggtga tggtacgctg
     5401 aaaggttcag gtcgctccat tcaggggctg catatgcgtg atgcactgga gcgattagac
     5461 acactctacc ctggcatgat gctgaagttt ggcggtcatg cgatggcggc gggtttgtcg
     5521 ctggaagagg ataaattcga actctttcaa caacggtttg gcgaactggt tactgagtgg
     5581 ctggaccctt cgctattgca aggcgaagtg gtgtcagacg gtccgttaag cccggccgaa
     5641 atgaccatgg aagtggcgca gctgctgcgc gatgctggcc cgtgggggca gatgttcccg
     5701 gagccgctgt ttgacggtca tttccgtctg ctgcaacagc ggctggtggg cgaacgtcat
     5761 ttgaaggtga tggtcgaacc ggtcggcggc ggtccactgc tggatggtat tgcttttaat
     5821 gtcgataccg ctctctggcc ggataacggc gtgcgcgaag tgcaactggc ttacaagctc
     5881 gatatcaacg agtttcgcgg caaccgcagc ctgcaaatta tcatcgacaa tatctggcca
     5941 atttagcgtc atcttctcta taaaaaagag cgtggattgg gtacaatccc gctcttatca
     6001 ccgcattttg actagctcaa taaaagaaat cagaccatgt ttgaaattaa tccggtaaat
     6061 aatcgcattc aggacctcac ggaacgctcc gacgttctta gggggtatct ttgactacga
     6121 cgccaagaaa gagcgtctgg aagaagtaaa cgccgagctg gaacagccgg atgtctggaa
     6181 cgaacccgaa cgcgcacagg cgctgggtaa agagcgttcc tccctcgaag ccgttgtcga
     6241 caccctcgac caaatgaaac aggggctgga agatgtttct ggtctgctgg aactggctgt
     6301 agaagctgac gacgaagaaa cctttaacga agccgttgct gaactcgacg ccctggaaga
     6361 aaaactggcg cagcttgagt tccgccgtat gttctctggc gaatatgaca gcgccgactg
     6421 ctacctcgat attcaggcgg ggtctggcgg tacggaagca caggactggg cgagcatgct
     6481 tgagcgtatg tatctgcgct gggcagaatc gcgtggtttc aaaactgaaa tcatcgaaga
     6541 gtcggaaggt gaagtggcgg gtattaaatc cgtgacgatc aaaatctccg gcgattacgc
     6601 ttacggctgg ctgcgtacag aaactggcgt tcaccgcctg gtgcgtaaga gcccgtttga
     6661 ctccggcggt cgtcgccaca cgtcgttcag ctctgcgttt gtttacccgg aagttgatga
     6721 tgatattgat atcgaaatca acccggcgga tttgcgcatt gacgtttatc gcgcgtccgg
     6781 cgcgggcggt cagcacgtta accgtaccga atctgcggtg cgtattaccc acatcccgac
     6841 cgggatcgtg acccagtgcc agaacgaccg ttcccagcac aagaacaaag accaggccat
     6901 gaagcagatg aaagcgaagc tttatgaact ggagatgcag aagaaaaatg ccgagaaaca
     6961 ggcgatggaa gataacaaat ccgacatcgg ctggggcagc cagattcgtt cttatgtcct
     7021 tgatgactcc cgcattaaag atctgcgtac cggggtagaa acccgcaaca cgcaggccgt
     7081 gctggacggc agcctggatc aatttatcga agcaagtttg aaagcagggt tatgaggaac
     7141 caacatgtct gaacaacacg cacagggcgc tgacgcggta gtcgatctta acaatgaact
     7201 gaaaacgcgt cgtgagaagc tggcgaacct gcgcgagcag gggattgcct tcccgaacga
     7261 tttccgtcgc gatcatacct ctgaccaatt gcacgcagaa ttcgacggta aagagaacga
     7321 agaactggaa gcgctgaaca tcgaagtcgc cgttgctggc cgcatgatga cccgccgtat
     7381 tatgggtaaa gcgtctttcg ttaccctgca ggatgtgggt ggccgcattc agctgtacgt
     7441 tgcccgtgac gatctgccgg aaggcgttta caacgagcag ttcaaaaaat gggacctcgg
     7501 cgacatcctc ggcgcgaaag gtaaactgtt caaaaccaaa accggcgaac tgtctatcca
     7561 ctgtaccgag ctgcgtctgc tgaccaaagc actgcgtccg ctgccggata aattccacgg
     7621 cttgcaggat caggaagcgc gctatcgtca gcgttatctg gatctcatct ctaacgatga
     7681 atcccgtaac acctttaaag tacgctcgca gatcctctct ggtattcgcc agttcatggt
     7741 gaaccgcggc tttatggaag ttgaaacgcc gatgatgcag gtgataccag gcggtgccgc
     7801 tgcgcgtccg tttatcaccc accataacgc gctggatctc gacatgtacc tgcgtatcgc
     7861 gccggaactg tacctcaagc gtctggtggt cggtggcttc gagcgtgtat tcgaaatcaa
     7921 ccgtaacttc cgtaacgaag gtatttccgt acgtcataac ccagagttca ccatgatgga
     7981 actctacatg gcttacgcag attacaaaga tctgatcgag ctgaccgaat cgctgttccg
     8041 tactctggca caggatattc tcggtaagac ggaagtgacc tacggcgacg tgacgctgga
     8101 cttcggtaaa ccgttcgaaa aactgaccat gcgtgaagcg atcaagaaat atcgcccgga
     8161 aaccgacatg gcggatctgg ataacttcga ctctgcgaaa gcgattgctg aatctatcgg
     8221 tatccacgtt gagaagagct ggggtctggg ccgtatcgtt accgagatct tcgaagaagt
     8281 ggcagaagca catctgattc agccgacctt cattactgaa tatccggcag aagtttctcc
     8341 gctggcgcgt cgtaacgaca ttaacccgga aatcacagac cgctttgagt tcttcatcgg
     8401 tggtcgtgaa atcggtaacg gctttagcga gctgaatgac gcggaagatc aggcgcaacg
     8461 cttcctggat caggttgccg cgaaagacgc aggtgacgac gaagcgatgt tctacgatga
     8521 agattacgtt accgcactgg aacatggctt accgccgaca gcaggtctgg ggattggcat
     8581 cgaccgtatg gtaatgctgt tcaccaacag ccataccatc cgcgacgtta ttctgttccc
     8641 ggcgatgcgt ccggtaaaat aagcattacg ttatgctcac aaccccggca aatgtcgggg
     8701 ttttttaatt gtgctgcgcg aaagcagaca acaattttct tgcttcacta ttggctgcct
     8761 gcatcaccat ccacggactg aacgcccacg gtgtggcatc aataccgtgt aatacatctg
     8821 ctaaatcaca ccattgataa tccatcactt catcatcgtt gatctgtaac gcactggtgg
     8881 tgcgtgcggc aaataccgga cacacttcat tttccacaat gccattcgga tcggtggcgc
     8941 gatagcgaaa gtcaggatag atagattcag gaggcgtaat ttccacgcca agctcataac
     9001 ggcaacggcg gatcaccgcg tcttcgttgc tttctcccag ttgtgggtgc ccacaaaccg
     9061 agttagtcca cacgccaggc cacgcttttt tgctcagtgc gcggcgggta actaataatt
     9121 gtcctttggc attaaacagc caactggaga acgcgagatg taagcgggtg tctgccgtgt
     9181 gtgcggcata cttttccagc gtaccagtgg gaactccctg tgcattcaat aaaatgacgt
     9241 gttccgtttg cataatttct cacatgtaat tctgatcact catcattata gataattgaa
     9301 gagtgaaatg attaaccaag tgagcgttta tcgacaaccg cccgttttga gcggatgccg
     9361 acaggtaaaa accatttaaa aaagtagcat catatatttg aagcgacttt caatggccat
     9421 tgcaacacag tcagaaatga caggaataga gagagtaaaa agcaacagca gactgaatat
     9481 agcgcgcatt aaaaaattca tattattctc catgctcatt tttcttcagc ttgcgcatca
     9541 gaagccacat acgtactgtc ctgactttta aatctttatc agagacggat tccttcacca
     9601 ggtcagcatg atgctgatag ccattaaaga agacattcag cacaacggcg ctaagggttg
     9661 cgagcataat gccgctatgc agcaacggtt gcagtacggc cggtaactta gaaaagaaat
     9721 cgtgagagag cgtcggagtc atgccaacgc cgagactgat cgccacaata tagaggttgt
     9781 aacggttggt ggtgtagtta cagcgcgaca gaattcgaat ccctgtcgcc agtaccatgc
     9841 cgaacatcac cagcccagcg ccgcccagca caaattgcgg aatggaggct accagcaccg
     9901 ccatttttgg caccatgcca aacaggatta atataattcc cgaagaaata cacacccagc
     9961 ggctatgaac gcgcgtcacg ctaaccaggc caacgttttg agaaaatgac gtgtggggga
    10021 agctgttaaa cgtgccgcct atcattgtcc ctacgccatc gacacgcagc ccgcgaataa
    10081 tatcgtgtga agagagttta cgaccgacta tttcacccag tgccaggaac atccccatcg
    10141 actcgataaa cacgatgatt aacacggcag tcatggtcag aatggaaacg ggatcgaaaa
    10201 tcggcatacc aaacgacatc ggggtgacaa tcgcaaacca cgaggcatca tgtagcccgg
    10261 ataaattgac ttcattcatc atccacgaaa gtaaaaagcc aaatacaatc cccagtaata
    10321 cggcgacgtt ggacataaat cctttcgcat agcgagtaat gagcaagata aaaattaaga
    10381 cggcaaagga gatacctaaa taaacgggat taccatattg cggattccct ttacctccgg
    10441 cggcccagtc aatacccacc tgaatgatgc taagcccaat agaagtaata accacaccgg
    10501 taaccagtgg cgggaataaa ggcatcaagc gaccaataag tggcgctaat aatgtggtga
    10561 taaaacccgc ggcgatagtg gcaccaaata tccccagcag gccgatatcc gggttcatcc
    10621 caatggctat cattggtgtt acagcagcaa aggtcaccga cataatcacc ggcaggcgga
    10681 tccccataaa gcggccgata ccgatacatt gcaataatgt gacgatcccg cagcaaaaga
    10741 gatccgagct aatgagcatc gcaatagctt cttttgagag gcccagtcgg tcaccaatca
    10801 taagaggaac agcgactgca cctgcgtaca tgacaaggac gtgttgcaga ccgagtatga
    10861 tcagctttcc tggtgataat atgcggtcaa cctcatcagt tgggcggtct tgcccagaag
    10921 atgagggaag ttgggaatct atggcgctca tcagtgtttc tcctttcgcc cgccagagta
    10981 aaaagcaacc gtttacgtta atgaaactgt ctaaacacat gctcgtggag tgccagtttt
    11041 tgcgaggaag gggagttaga gacaggaatt gcggaggcaa tcacataatc gtgcttaaac
    11101 cacgaaaatg agaagagaac ctgacaatga aattatctgt aattttctca tattgatatt
    11161 tcattaatca ttctggcatg tcgcactctc gcatttaatc gtttttatct ggatagcgct
    11221 cttttggtcg gcaatgttga aataatgaaa gcggcataga ttgaggggca ataatttgaa
    11281 ctcagtcgca aaattataat taaaacggtc atgctaccta atatatgccc gtttattgca
    11341 tcgcgaaatt tgagaagaca taactcatta aatgaaaggg atgcaaatga ataagtttat
    11401 cgctgctgaa gctgcggaat gtataggctg tcatgcttgt gaaattgcct gtgcggtggc
    11461 acacaatcaa gaaaactggc cgctgagtca cagtgacttt cgaccgcgta tccacgttgt
    11521 agggaaaggc caggctgcga atccggtggc ctgccatcac tgcaacaatg ccccttgcgt
    11581 tacggcttgt ccggttaatg ctctgacttt ccagtccgat agcgtacaac tggacgagca
    11641 aaaatgtatt ggctgtaaaa gatgtgcaat cgcttgcccc tttggcgtcg ttgagatggt
    11701 cgatacgatt gcgcagaaat gcgacctttg taaccagcgc agttccggca cgcaagcctg
    11761 tattgaagtc tgcccaacac aggcgttacg actgatggac gataaagggt tacagtggat
    11821 aaaggtggct cgccagcgca aaacggcagc aggaaaagcg tcatcagatg ctcagccatc
    11881 tcgcagtgca gcgttgctcc ccgttaactc gcgtaaaggc gcagataaaa tttcagcgag
    11941 tgaacggaaa acccactttg gcgaaatata ttgcgggctg gatccactgc aagcgactta
    12001 tgagagtgac cgctgtgttt attgtgccga aaaagctaac tgcaactggc attgcccgct
    12061 gcataacgct attccggatt acatccgtct ggtacaggaa ggaaagatta ttgaagcggc
    12121 agaactttgc caccagacca gttccttacc agaaatttgc ggcagggtat gtccacagga
    12181 ccgtctttgt gaaggcgcat gtactttgaa agatcactcg ggcgcagtct ctatcggtaa
    12241 tctggaacgc tacatcaccg ataccgcgct ggcgatgggc tggcgtcccg atgtcagcaa
    12301 agttgttccc cgtagcgaaa aagtggcggt gattggcgct gggccagcag ggttagggtg
    12361 tgctgatatt ctggcgcgcg cgggagttca ggttgatgtc tttgatcgcc atccagaaat
    12421 tggcggtatg ctgacttttg gcattcctcc tttcaaactc gataaaacgg tattaagcca
    12481 gcggcgagag atattcaccg caatgggaat cgactttcat cttaactgtg aaattggccg
    12541 cgatattacc tttagcgatt taacttctga atatgatgca gttttcatcg gcgtggggac
    12601 ttacgggatg atgcgagcag atctgccgca tgaagatgcg cccggtgtca ttcaggctct
    12661 accgttcctg actgcccata cccgccagct catgggattg ccggagtctg aagagtatcc
    12721 gctgacggac gtggaaggta agcgagtcgt ggtattgggc ggtggcgata cgacaatgga
    12781 ttgtttgcgg acttccatcc gcctcaatgc cgccagcgtg acctgcgcgt atcgtcgtga
    12841 tgaagtcagt atgccgggct cgcgcaaaga ggtggttaat gcgcgcgagg aaggtgtcga
    12901 gtttcagttc aatgttcaac cgcaatatat cgcttgtgac gaagatgggc gtttaactgc
    12961 ggtgggcctg attcgtaccg ccatgggtga gccggggccg gatggtcgcc gtcgtcctcg
    13021 tccggtagcg ggttcagagt ttgaattgcc cgccgatgtt ctgattatgg cctttggttt
    13081 ccaggcgcat gccatgccgt ggttgcaggg cagcggaatt aaactcgata aatggggcct
    13141 gattcaaacc ggtgacgtcg ggtatttacc tacccagacg catctgaaaa aagtctttgc
    13201 tggtggtgat gcagttcatg gcgcggatct ggttgtcact gcaatggccg caggaaggca
    13261 ggcggcgcgc gatatgttaa ctctgtttga tacgaaggca tcgtgatgaa atcgttaatt
    13321 atcgttaatc cggctgactg tattggctgc cgtacttgtg aagtagcctg tgtggtcgct
    13381 cacccttcag aacaggagtt gaatgccgat gtctttttac cccggctgaa ggtacagcga
    13441 ctggacagca tcagtgcgcc ggtgatgtgc catcagtgtg aaaacgcccc ttgtgttggc
    13501 gcttgccccg tgggggcgct gacgatgggc gagcaggtgg tgcagaccaa ttctgcccgt
    13561 tgtattggct gtcagagttg cgtcagtgcg tgcccgtttg gaatgatcac cattcagtcg
    13621 ttgccggggg atacccgaca acaaattgtg aaatgcgatc tctgtgaaca gcgggaagag
    13681 gggccagcct gtgttgaatc ttgcccgaca caggcgctgc agttgcttac tgaaagagaa
    13741 ctcaggcgag tccgccagca gcgtattgtt gccagcggtg agaatcctct gtgaaagaaa
    13801 tctccgcgct gaaaggcgcg gagaatctat tagattgccc aaccacccgc gtaaaatgcg
    13861 accagtgcgg cagtaatgat caccgtacca atattcaact tttgccattc gcgagcaaag
    13921 acacggccta cgaccagtgt cacaaagccc agcataatac cggtaacgat attacaagtc
    13981 agaacgatga acacggcaca caccaggcca gccattgcgt caataaaatc gttgaaatcc
    14041 agcttcgaga cgttacttaa catcagcaaa cccacgtaca tcagagcggg tgcagtggcg
    14101 taaccaggga tcaaaaatga cagcggtgat aagaacagaa tcagcaggaa taacgccccc
    14161 actacggttg cggtcaaccc tgttttaccc ccggcggcgg ttcctgccgc tgattcgata
    14221 taaaccgctg cgggcgctgc gcccaccaga ccggagaata ttgaacttac tgagtcactg
    14281 gtcagggctt tgccgccatt gatgatctgg ttgtctttat ccaacaaatt cgcctgaccg
    14341 gcgacggcac ggatggtgcc agtggcgtcg aacactgcgg tcatcaccaa tgccagtaca
    14401 ctcggaagta cggttggctg gagtgcgccc ataatatcga ggctgaaaat cagagactta
    14461 ccatcttcgc cagtcagact tggcatcgcc accagaccgt ggtatttcac cgctgggtca
    14521 aagattaagc cgataatcga aattgcgata atcaccaaca agatcccgcc gggtacgcgg
    14581 cacttctcca gaccgaagat gaccgccagc cccagcaagc tcatcatcac cgggaaggag
    14641 gtaaacgcac cgagcgccac tggcaagcct tcaatcgggt ttttgataac catacccaca
    14701 ccgttagcag caatcagcag cagaaacagg ccgataccga tacctgtacc gtgagcgata
    14761 cccatcggta aattacgtaa gatccaggta cgcacaccgg ttacggaaat agcggtgaag
    14821 atgacgccca tcagaaagac cgcgcccagt gcgacaggaa cgctaatttg ttgcccgagt
    14881 accagactga atgcggtaaa tgccgtcaag gaaatcgcac aaccaatcgc cattggcaaa
    14941 ttggcccaca accccatcag caacgagccg aagcccgcga ccagacaggt ggcaacaaac
    15001 acagctgcgg gaggaaaacc tgctttgccc agcattcccg gaacgacgat aacggaataa
    15061 accatggcca gaaaggtcgt taagccagcc agtacttcct gacgaacggt actgccacga
    15121 gcggtaattt taaaataatt atccagcgcg ccctgtggct ttggtgcgtc cggtgtttgt
    15181 aggatgtctc cagacataat gatgtcctca cgaggatgtt aaagttttat tattagttgc
    15241 gttcgtacac cagacgacca tcaacgtagg tgcggtagat cgaacggtca tcgcccaacg
    15301 tcatcatcac gaacaatttg tcgactaaag aaacagagtt gtcatagcgc agctgctgta
    15361 gcggagtggc ggtgggttcc atcaccacga aatcagcctc tttgccaggt aaaaagttgc
    15421 caatcaaatc gtcaaggccc agagatttcg ctccgccgag cgtggccagg taaaacgctt
    15481 catatgccga gaggcgatag ccttgtaatt gcaatacttt gtaggcttcg ttcagcgttt
    15541 gcagcatgtt gaaagtggtt ccggcaccga tatccgttcc catgcccact ttaactttct
    15601 tctgccatgc ttttttcaag ttgaataagc cgctgccgag gtaaaggttg gaggtcggac
    15661 agaaagcaat gctggatttg gtttcgctga gacgatccca ctctttttct tcgagatgga
    15721 cgcagtgagc aaagacacag tttttaccgg tcaggccgta ctgatggtaa acatccagat
    15781 aaccatcatg gtcaggataa agcgatttca cccaggcaat ttcatctttg ttttcacaga
    15841 gatgggtatg tacccacgta tccggatatt cttctttcag gcgttgcgcc atcgccatct
    15901 gttcaggaga tgaggtcggg gcgaagcgtg gcgtaatcgc atatagcaga cgaccatttt
    15961 tgtgccagcg ttcaatcagt tctttgcttt ggtgatagct gctttcggca gtgtcgagca
    16021 gataatccgg tgcgttgcgg tccatcatca ccttaccggc aatcatacgc atattgatat
    16081 gactggcggc ttcaaacagc gcatcaacag attgcggatg aacagtgcca aacaccagcg
    16141 ccgtggtggt tccgttacgt aaaagctgct tgatgaagaa tgccgacatt tcgcgggcgt
    16201 actctaaatc ctcataacga cgttcagtag ggaaggtgtg tttattcaac cactccagca
    16261 attgttcacc ataggccccc accatttcac tttgcggata atggatatgt gtatcgacaa
    16321 agcccggtac tatcagtttg ccgcgatagt cgcgcacgcg aatagtgtca ggaatttgat
    16381 gctttccgtc ttcccattcg ccaaaccatt ccacttttcc ctgtttaatg agtaataaac
    16441 catcctcaat aaaccgcagc gcagaggcaa tctcttccgg gttatcgacc gtacgggtga
    16501 catcaataaa actgcctcgt accgctttca acgtgtgttc tcctgacatc attgactcct
    16561 ttactgttaa tccatctctt ccgctgaggt aataccaggc agaacgtttt cctgtcggta
    16621 gccaccaggg aggataatat ttaataaaat cgcagttaac ccgccagcac aaatagggtt
    16681 ttcaactagt acataaatag aggctggcaa tattttaaaa atttcgggat cgtaggagac
    16741 gccaagtcct aaacctaaag aagtggcgac aataagtgtt tctcggcgct ttaaaccgtt
    16801 ggtgatgatt atgcgaatcc cagcgatggc aatcatggaa aacatcaacg tcattgcgcc
    16861 tcccagaact gccgagggaa tggtcgtgaa gaagccgcca atcatcggaa acaaaccgag
    16921 gataaccagc attaccgcga tggttcgccc gacataacgt gaagcgacgc cagtcatctg
    16981 aataacccca ttattttgcg caaacgtggt taagggtaat gacccgacag cggaggcgat
    17041 aacagaaacc agaccgtctg ccagcacgcc gcctttcagt cgggactgat actcttctcc
    17101 ctgaatgggt cggcgggaaa ccattgccgt ggcggtgata tcgccgacag cttccagcac
    17161 gctaagcaga taaatcgtgc caaccaccag gaactgatgg aagctaaaac taaagccgta
    17221 tttgaacgga tgcgggatgg tgattaacgg caaattgcgc atactgctga aatccaccat
    17281 gcccaggcat aacgatgcga tatagccgac acatagccca atggcgatcc ctcccatgcg
    17341 tagcaacgga ctgcgacagc agttaaagcc gatcaccaca attaaaacca ataaaccaac
    17401 gccgagatgt tcgtaattgc cgaatgtacc gctgcttttg gctgcaaatc ctccaccaaa
    17461 atcgataatg ccgactttaa tcaggcttaa gccgatcatc agtaccacaa taccgctgac
    17521 ggtaggcgta ataacccgac gtaaataggg caagataaat gaagatccga caaccagaaa
    17581 tgcgccaacg aaggagacgc cgagaagcga cgacatgatt aactcttcgt gaaaaccgtc
    17641 gcttttcatg ctgctgccca gcgcaatcat gaccgtaaca aatgaaaaat tgactgactg
    17701 aattgagagt aggccagaac cgacgatgcc gtagcggttt acttgtaacc aggtaccaat
    17761 accagaggcg atcatcgcca tagaaacaag ataggcagtt gtttcagcgg aaagctgtaa
    17821 ggccgccccc acgattaacg cgggggttac catcggaacg aaaattgcca acagatgggt
    17881 aatggcacca acgagagcct gatgaaaggg agggcgatcc tccagttcaa atataaggtc
    17941 agaacctgca ttgtttatat cagacatccc ttcactcctt ttaaagtaaa tttgatcatc
    18001 tgaattagta aaataaattc ccacgaattt ggggcgcagg acgccttgag aacggcttat
    18061 ctcattttcg cagtcactat ttagtcatcg tccaaacaga gaaacaggcc gccgaagcgg
    18121 ccatttatta tttatatttt ttccagcgca gtgagtattt tctccggtgt gaaatgccat
    18181 tcgcgtaacc agatgccgca tgcatcgtga attgcggtag caatcgccgg agctgcgcca
    18241 tttacaccga tttccgagat cgatttcgcc ccgaacgggc cgactttatc gtcgctcggc
    18301 accagcacag cgcggaaatc acgcggaatg tcaccaattt tcggtgcgcc gtaactgcgt
    18361 aaatcacgcg ttaacgggtg accttcggcg tcataaatga tctcttcgct catactgtgg
    18421 ccgatagctc gcagggtagc accgtagatt tgtcccaatg ctaattccgg gttgaccggt
    18481 gtaccgcagt ccagcaaggc gtagaattta tccaggcgga tttcacccgt acgcgtgttg
    18541 acggcaactt cagcgaagtt tgcgccatac gggaaggcga aatcaggcgt gatataactg
    18601 ccagttccca ccagtgaacc aaagccggtg ccggtttcgc ctttatgagc aatatccccg
    18661 aagctgactt cgcctttctt gccgcgcacg acgcccggcg ttgccagttg aacatctgcc
    18721 actgcctcac ccaacatttg cgcgccgtgg aacagaattt tctcccgcag attttccgct
    18781 gccaaacgcg ccgcgttacc cgagaagcaa gtaccggacg aggcatatgc gcctttatca
    18841 aacaacgcat gatcggtatc accggagata acatgcacgt cctgcggtgg gcagtgcagc
    18901 acttctgctg ccagtttcgt cactacagta tccagaccag taccaatatc cgcaccgcca
    18961 gaatgaacga taaaggtgcc gtccgattcc agtttgatca tgcagttagc ctgatcgata
    19021 tccgggatac ccgatttctg catgataatg gcgacgccgc gaccgatgtg ccagtcacta
    19081 ttttgcggtt tcggtgaaga ccattggatc atctcgcgac cctgacgcag gatctcttcc
    19141 agtgcgcagc tggcggcgga aggaacggag gtcggcgctt taccttcacc gattgcaccg
    19201 agaattttca gctcttgccc ttcgtgtacc cggttacgtt cgataatttc cagttggtcg
    19261 atctgtaact gttcagccag ttccgctaat gccatggtga tagcgaagtt acctttcggt
    19321 gcgccataac cctgataagc accatttggg caaatgttgc tgtagtaggt ggtgacctgg
    19381 aaatcgacgt tatcgcacgg atataacggc agcgacagcg ccggtccgtt acacggtacg
    19441 gtgagtgagt ggttgccgta agggccagtg ttggcgcgga aatccatctt cactgccgtc
    19501 aggcgaccat cttttttcgc tcccagtttg acggtgactt tcgcgacgtg acgagaggtg
    19561 ttagcaataa actcttcttc acgggtgtag cggaacagta ccggacgccc ggtcacgcag
    19621 gttgcccatg cgcacacttc ttccagcagg atgtcctgtt tggagccaaa accgccgcca
    19681 actcgctctt taatgacatg aactttatgc tgtttcatgc ctacgaggcg cgcgacctgg
    19741 cggcgtaagt gccatggtac ctgggtggag gcgtggataa ccagacgatc gccgtccatc
    19801 cgggtaaagc agatatgtgt ttcagtcggg cactgctgtg cctgcgttga gttataggtt
    19861 cgctcaatga tcacatcggc atcggcaaag cctttgtcca tatcgccaat atgaccatga
    19921 atactggcgg cgatattttt gcgagggcga gaaccgatcg ggaagttgat gatcatatgc
    19981 tcgccgcgct gggctgcatg gctgttatcg tcttccagag tatctggcgc accagcaaca
    20041 tacaccaccg gttcatcgtg cacgacaggc gcatcttccg ccattgcttc gtcgatcgac
    20101 attaccggct taagcacttc atattcaacg tcgatgagct tcaatgcttc gagcgcaatt
    20161 tcttcacttt ctgcgacgac cgcagcaaca cgatcgccga cgtgacgcat tttcttgccg
    20221 aacatacggc ggtcaagcgg tgacggttcc ggtgcgctct gaccacccgg ggtatagtag
    20281 atatccgggc aattcaggtg agtaataacg tgaacgacgc ccggtaaggc ttcagctttg
    20341 ctgacatcca gatgagtaat cagtgcgtga gcgtgtgggc tacgtaacat tttaatgacg
    20401 caggcgtcag ccgttacgcg gtcttcaaca tagcagggtt tcgcctgcac cattttcgcg
    20461 gcatcagttt taggataatg cttgccaatg acttcaaggt cgtcacggaa agtcggagcg
    20521 atatcaatgg tggcctgcgg attattttta cgtgcaaccg ccagttcaat gacctgatag
    20581 tattgttgcc agcctgcatc gcggctgaac aaaccagaaa gcgcgtcgtc gatctcttcg
    20641 cgggtaggtg cggcgatgcg atcgagaaga tcggtgataa tcagagctgc agctggatcg
    20701 ttataaccag actgcaccac gccaacatca accattgcct gttgaaccag acttaactcg
    20761 ttccatttgc ccaaagattc tgcggtacga atatctgcct tctctaactg tgcggcaata
    20821 agcaaggacg cgttaacgat attaccgtta aagattattg cgtcagaacc ggcaaacccg
    20881 aagccatcat cactgttgcg tacagagtgc attcccatgt taaacaacag cttttgcacg
    20941 ttttcgcctg gattaacggt tagctcctga ggcgcgccat ttaaagtaaa gtggatgatc
    21001 atacggcttc ctccccagcc tgttggcagt cggcatacag gtcggctacc agaactcccg
    21061 tgatatagcg tttataggcc acgctgcccc gcaaatcttc ctgcgggaaa atggcgttgg
    21121 cgacagcctg ttcaagtgca ttgccttcca gattttgttt ttcgacatca tgcagacgca
    21181 gtgctttact ggcgacgcca tccagcgcaa ttcgcatacc gtcgtggtct gtcattgcaa
    21241 cggctgccgt cacgacggtt aaacctgcct gagaacggct aattttgcgg gtcgcacagg
    21301 tgcgatacgg atctttaatg ataatttcgg ttagcaggcg atcgcatggg caggccaggt
    21361 agtcctcgat tgacagcgtt tcgccgttgc caaaaaccag ttcagcatcc agtgccaaca
    21421 ggacgggaag cagcaccgac tcttcctggc gggcggcgat ttcaccacca atggtcgact
    21481 gattacgaac atggcgtgag taaacaaaac cgagggcttc acgcagcgct gcaggaataa
    21541 atcgcgcatc acgcagtggc tgcaagcgag acattgcgcc aatccgcagt gcaccgttat
    21601 cccagtcaac ccagtccagt tccagatcct gtaaggaaat ggcaatcttt ttatcggtac
    21661 gggttggtgt agcattgagt ttgctgcccc cggcgaacca gacggcttca tcctggtagc
    21721 ggcgcttcag ttccagcgcc tgttcgacag agtcgggcct gaaaaattgt tcaatcatct
    21781 tctttcctta tttaaccctc ttccctgcgg gaagagggca tctgtcattt atgccagcgc
    21841 atccatccga cgccacatac tggcagcggc ttttctggct tgtgcataaa tggaatcgca
    21901 atcgaagtta aactgacggt cttcatagac catcacacca ttgaccatca cgctgtgaac
    21961 gctgcctgag cccataccga aagcgatatg cccggcgata ttgtctgcca gcagcggcgt
    22021 cggtgagttg taatcgcaaa tggttaaatc agctttgtaa ccggcttcca gaagtccaaa
    22081 tttcgcgcca aagttgcggc tcatcagttc gttaccgtta gtcagggctt tggcaaaact
    22141 gtcaggccac agcggaccac ccgcatcgcg atgtttaaag aaggcaaatt tcatctcttc
    22201 aaacatgtcc gaaccaatgc cgtccgttcc caacgccaga ttgcggatgt cgctaaggtg
    22261 atggttgtag ccgacatggt tgttcatgtt tgaacgggcg ttatgcacca ggaacgcatc
    22321 gcgctgattg agtagggcga tgtcatcttt cgacaagtac agcccatgag cgaccagcgt
    22381 tttgctatcg atgagatcga attgcgccag tcgtgccagc aggtctttgc cgtaccagtg
    22441 gtgactgtag gaaacgtcgt aaaggtcttc cgcagcgtga atatgcaaac cacggcctgt
    22501 ggctttcacg gcttcatgta gcatctccag accggcatct ggcacggtaa acggcgcgtg
    22561 agcaccgata tgtgcttcca ccagatacgg ctcggttgct gctttcttcg cctcatcaat
    22621 ctgacgggcg aagcggatgt tttcttctac accttcctgc aactctttga tgccgttgtt
    22681 acggtcagta gtttcaaaac aggtcatcgc gcgcaggcca acttttaaaa atgcgtcgcg
    22741 caatgtggag agcgacccgc cgatatacgc cggagaggca tggtgatcga taaccgatgt
    22801 acatccgctc ttaatcgctt ccagggaaca aatcagcccg ctgtaataga gcgactcttc
    22861 atcaagggcg cgatcgagcc gccaccagag atttttcagc gttgagatga aatccgggca
    22921 gggggcgatg tttgccataa ttccgcggga aagccccgag taaaaatggt tgtgcgagca
    22981 gacaattccc ggcatcacaa tccgaccatg catctctttg tagctggcat cggggtagcg
    23041 ttgcgtcagg gcatcgccga tagcgacaat cacatcattt tcgatagcga tatcaacgcc
    23101 ttcctgcact ttcgccgggt gtaactgcac tgcggtgaca ttcttcagaa tcaacatgat
    23161 tacacctcca cgcggcccag cagataatga tgatgctggt ggacatggct gatgatgcgg
    23221 cacatatcgt tcagctccgg tggtacgttg ttgaactgac cttcgctgtc gatgtttaac
    23281 acccagcttt ggttattcag tcgtactcgt acccggcaat cttccacaag gaagcctggg
    23341 ttgctgctgt tatcaaagtc ttgcgccagg ctgaaaacgg tgattttgtc tttgtatggt
    23401 ttaccgttcc acggacagaa ctgagcgcag ttgccgcatt cgttacagta agcgtcgagg
    23461 tgcagcgtct ggaatctatt ctggaagcct gggaccgcaa tggagacgtt ggcgcggttc
    23521 gggcagacat ccacacactt gctgcaaacg tagttacatt cgaggcagcg agcggcttcc
    23581 tgggcgacaa acgcgtcacg atcgtcactg ttcaccagag tgatagagat atcgccttta
    23641 cgttgataga tttccgccgg attgacgttg ttccagtatt tatcgttctg gtgggaacgg
    23701 atattttccc gactaaggat ggcatcggtc gcccgacgcg cggttccgac agcagcgaca
    23761 atggaggatg gtccgcgctg tacgtcgccg atcataaaga cgtcagtcag acgagtttcg
    23821 ccattgtggt cgacgtctgg ccagccgttt ttgtccagcg gcacgcccat cgcattcagg
    23881 gcttcagtat cctgctgttc accaatggcg gtgatcaggc tgtctacatg cagtgttact
    23941 gtttcgttgg tttcaaccgg acggcgacgg cctttctcat cgggttcgcc aagcgacata
    24001 acgcgcaagg ttaaggtgcc atcagcatcg aaacgttccg gattattcag gaaacggaac
    24061 tccacgccgt cgtgcaacgc ttcttcatac tcttcgcgcc atgcgggcat ctcttgcagt
    24121 gaacgacggt aaacgatcgt tgctttttct acgcctggaa cgcgtaacgc cgcacgagcg
    24181 cagtccattg cggtgttacc cgccccgaca acgaccacat gtttgcccag cttgagcgct
    24241 gtacccttgt tgtattcacg caggaagggg agtgatttcc aaacattttg gttgtcaccc
    24301 gccagtttca caccgctatt tttatcagtg ccggtggcaa tcagaacata gtggaagccc
    24361 tgatttttta actgttcaac ggtcaaatcg ggtgagcagc catactcaaa tttcacgccg
    24421 tgatcggcaa caaaatcgat atcgtgctga attaactcag ccggaattcg gaactgagga
    24481 atgatatttt tcaccacgcc gcccgcattg gcttcgcgtt caaacagcgt aaccggatgg
    24541 cccgctctgg caaggaagta acctgctgcc agacccgccg gacctgcacc aatcacggca
    24601 accggatggc gtgaaccaga accggctggt ttgtgccagc gttgcttata ttcatcccaa
    24661 cctttttcca gcgcgacttt tttcagttcg cggatattca gcgcactgtc gtaatccagg
    24721 cgggtacagt tgtattggca ctggtgatcg caaatatgac cggtaatggc gggcagagcg
    24781 ttgcgttggt agatgagttc cagcgcgtcg gcatagcggt gttcgccaag cagacggatg
    24841 tattccggaa tatcttgctt gatagcgcag gcagtaacac agggggcaac gtagcaatcg
    24901 gtcagcggca ggtcttctgc cacttcaata cgctcttctg gcttccagtg tttctgggtg
    24961 tattccatgg ttaacgcatc tgctgccagt ctgttcagtc gttcgacgtc aacatggtca
    25021 agtccccagg cgtcggagcc ttccagctcg cgcatgcagg cacttaagcg caaatagccg
    25081 ccaggtttca gcaggtcggt tgccatagta atagggcgaa tacctgtatc aaaaatatcg
    25141 cggatagtca gctgactggc accaccggaa taagaaatgg gcagtttgcc gtcaaaggcg
    25201 cgagagagaa ctgctgcaac attgatggag agcgggaaca gcgcacggcc tgacatatac
    25261 atctcttcac caggcagtgc gcctttattg ttgatggtgc cgagagtgtt agtcagtttt
    25321 acgccaaagc cgagtgattt ttcttttgcc agtgccatca ggcgttccag catttccagt
    25381 gcttgcgtca gcttgaggtc gtgatcaaat gactcttctt ttaagcctat gtaaccgaaa
    25441 ccgcagacat cgaggatctc acgaacacgc gcgtatccca gtaaggtcgg gttaagtttc
    25501 acaaaggtgt tgagcccttt ttcttccagc atgtagcggc aaatggcttc gatttcatgc
    25561 ggaggacagc cgtgcatggt ggagagggtg acgccctgca ccatactggt ggggatgcga
    25621 gcgggtaagg cttgcaagct ttcgcgtttt tcctgcaatc cgtggcgggc taaaaatgcg
    25681 tcatcctgga gtaatttatt cagcgtatcg cgatattgcg cgaatttcgg atggtcagat
    25741 gcgtccatca tattgtcgat gaactgttgc attggcggtt gcttaatacc ttcgaggttg
    25801 taaccgacgc tcatattaaa gatgaacgat ttaccggaat cagaaggctg gaacatcgct
    25861 tcgagaaggt gcagggcaaa ccaggctttg aggtattcat cccaggcttt aagcagggta
    25921 aattcggtag accattcggt gttaaagcac tcgtcttcgg catcgataca gggcttttcc
    25981 agctccaggc ggtcaagaat ttggacggtt tttagttcga tgaagcgtcc gccagtcagc
    26041 caggaagtga caatattttg cgcgagctgc gtgtgcgggc cagcggcagg gccgacggga
    26101 gtggcacagg tttcaccgaa gacgctaaca gttttacctt ttacaggtga gtaaaactgt
    26161 tgctcgggaa taccaaagat tgagcgttgt tgttggtatt catcaaatat gcgcgtcaaa
    26221 agttcctcaa acggaatggg acgcataata tcccccataa ccctctcctt agcttataca
    26281 gatatcattg agtgaccggt gttgagaaat ccggtggttt agggggatag agcaacaatc
    26341 gcaccactct tgccaggttt ggcgggaaat ataaaaaaat gtgaggcggc tcgaaactta
    26401 aaggcttttt gtgaatgaac tcacaggtgc caaatgagaa ttaaaatcac tcctgaaaat
    26461 tattattgtc agcccattta tcactttttc tcttttctca aaatcagtga ttccttatca
    26521 ttatgataaa gagtgctgga gagattaaat atttgaacgc aatcgtttaa ctacattttc
    26581 taaattttag tatacctttt ttgcgctgta ataaagtcgt ccggagtatc aatatctaaa
    26641 attatttctg cattttctat ctcgacggaa taatgagctc ccataaggag tgcctgacgc
    26701 atattggtga cattgggtcg ttggattgcc tgcatcaagc atggttttga cactaaaatc
    26761 ggatggccgg ggatgccatt atggagtggc agtattgcgc catcatttcg taacgaccag
    26821 atttttctaa aaatatcgat ggtgagggtt ggcatgtcac cgtgggtgag aaaacaatgt
    26881 tctgtttgca ctgcgggtac tgcggccttt actgatgtta gtaaaccctg cgcataatct
    26941 gggttgtgga taatagtgat attgctctgg ttcgcataac gttcgtgcag ttcattacca
    27001 cgatagccgg tgactaaaat aattcggcta caaaactgca acgcattttt gatacttgta
    27061 tcaagaattg tcccctgttg ccagggtaac atcattttcc attgccccat tcttgatgat
    27121 aatccggcag cggtaattat acagtcgatg gctgacatag tggttccatt atttataggg
    27181 gctaataacg cctgataatt gcgttacttc ctgatggatt aagttgggga taatttatcc
    27241 cagagaggtc ataaagactc gtgaaaagta tagttgaccc atcggcatta gtcattgatt
    27301 taggtgcgca gaaacgtccc actgtgattt ctgttgttgg tgctgggggg aaaaccagct
    27361 tgcttttttg gctggcagaa ctgctccagg ctagcggcag gcgtgtgtta atcacgacga
    27421 cgacacatat gtttatgcca acgtctcact ggcccgtggt tttctgtcgt gatcccgcca
    27481 tgcttcctca tgcgtctctt acatccccca tttcattttg ttttcacagc tggaaagcga
    27541 accagggaaa agtgcaggga tttacgccag aagcgattga tgcactggtg caacgaccag
    27601 agtgtgacgt aattctcatt gaagcagatg gctcgcgtgg aatgccgtta aaagcgcctg
    27661 atgagcacga accttgcata cccaaaagca gttgctgcgt gattgctgtg atgggaggac
    27721 atactttggg cgcgaaagtg agcacagaaa atgtccatcg ctggtcgcag tttgctgata
    27781 ttaccgggtt aacacctgat gcaaccttgc aactgagcga tctcgttgcg ctggttcgcc
    27841 accctcaggg ggcgtttaaa aacgtaccgc aaggttgtcg gcgagtctgg ttcattaacc
    27901 gtttttctca atgtgagaat gcgattgcac aaagcgagct ccttcaaccg ctgcaacaac
    27961 acgacgtaga ggcaatctgg ctgggcgata tacaagaaca tcctgcaatc gcgcgcagat
    28021 ttgtgaatta gcggcccggg tattccgggt tactgaaagg atatccattg aggttggtat
    28081 gaatattttc acagaggctg caaaactcga agagcaaaat tgtccgtttg cgatggcgca
    28141 aattgttgat agccgaggct cgactccccg ccattctgca caaatgttag tgcgcgccga
    28201 tggttctatc gtcggtacaa ttggtggcgg aatggttgag cggaaggtga ttgaagagtc
    28261 acttcaggca ttgcaggaac gtaagccgcg attattccat ggacgtatgg ctcgtaacgg
    28321 tgcggatgct gtcgggtcag attgtggagg tgcaatgtca gtatttatca gcgtccatgg
    28381 tatgcgtcca cgtctggtgt tgattggcgc ggggcatgtc aaccgggcga tagcccagag
    28441 tgcggcgcta ttaggatttg atattgccgt tgccgatatt tatcgcgaaa gcctcaatcc
    28501 tgaactattc cctccatcaa ccacgcttct ccatgctgag tcgtttggtg cagcagtgga
    28561 agcactggat attcgccctg ataattttgt cctgattgcc acgaataatc aggatcgtga
    28621 agccctcgac aaactcattg aacagcccat tgcatggttg gggttgctgg caagtcgccg
    28681 caaggttcag cttttcctgc gtcaattgcg tgagaaaggc gtggctgaag aacatattgc
    28741 ccgtttacat gcgcccgttg gttacaacat aggtgcggaa acgccgcagg agatcgccat
    28801 cagcgtgttg gcagaaatat tacaggtgaa aaataacgcg ccgggtgggc tgatgatgaa
    28861 accttctcat ccttccggac accagctggt ggtgattcgc ggtgcgggag atatcgccag
    28921 tggtgtggcg ctacgtctgt atcatgcggg ttttaaagtg atcatgctgg aagtggaaaa
    28981 accgacagtg attcgttgta cggtggcgtt tgcccaggcc gtgttcgatg gcgaaatgac
    29041 ggtcgaaggc gtcactgctc gcctggcaac cagctctgcg gaagcgatga aacttaccga
    29101 acgcggattc atccctgtga tggtagatcc cgcctgttca ttgcttgatg aactgaaacc
    29161 gctttgcgtg gtggacgcta ttctggcgaa acagaatttg ggaacgcggg cagatatggc
    29221 accagtaaca atcgcgcttg ggccgggctt tactgcaggg aaggattgtc atgcggtaat
    29281 tgaaacaaat cgcgggcact ggctcggtca ggtgatttac tctggttgtg cgcaggagaa
    29341 taccggtgtt cctggcaata ttatggggca taccacccga cgggtgatcc gtgctcctgc
    29401 tgcaggcatt atgcgatcca acgtgaaatt aggcgatctg gtgaaagagg gcgatgtgat
    29461 tgcctggatt ggtgagcatg aaattaaagc accgttgacg gggatggtgc gtggcttgtt
    29521 gaacgacggc ttggcagtgg ttggtggttt taaaattggt gatatcgatc ctcgtggtga
    29581 aaccgctgat ttctccagcg tttctgataa agcccgggcg attggcggcg gcgtacttga
    29641 ggcgttaatg atgttgatgc atcagggcgt gaaagcgaca aaagaagtgc tggaagtggc
    29701 ttaaatgaaa atggccggat ggtattaccc acccggcctt aaaattactg acaaatcacc
    29761 gttccggttt tgccttcaat cccttctttc gctttgctca atacggtaat cagtgcttca
    29821 cgacctgcgc gagagcgagc aaacgaggcg gcagcttcca ctttaggcag catagaacct
    29881 ttcgcaaaat gaccttcttc gataaagcgt tcagcatcac ttaatgacag gcgatcgagc
    29941 cactgttcat tctctttacc gaagttaatg gccacttttt ctaccgcagt cagaatgatc
    30001 agcatatcgg catcaatcat ttctgctaaa cgggcgctgg cccagtcttt atcgataacc
    30061 gcgctggcac cacgcagatg gttaccttca cgaataacag gaataccacc accgccaacg
    30121 gtgatcacca cctggcctgc atctaccaga gctttaaccg tttctttttc aataatatca
    30181 accggttttg gcgaggcaac aacacggcga tagccgcgac cagcatcttc tttcagagtg
    30241 taaccctgtt ttgtcagttg ctctgcttct tgctcggtaa agaacgaacc gatcggcttg
    30301 gtcgggttga ggaatgccgg atcgttagcg tcgacttcga cctgagtaac cagcgttgct
    30361 accggtttat taatgccccg agaaagcagt tcttctctta aggcgttttg tagatcgtaa
    30421 ccaatataac cctggcttaa ggcaacgcag acagacatcg gcagcattgg cgagtgcgct
    30481 tcagtttttg cagcagcttc aaaggcctgg ttaatcatgc ccacctgcgg cccgttacca
    30541 tgagtgacga taacttcatg tccttgggca attaaatcaa caattgcctg agaagtaatt
    30601 tttaccgctt tcatttgtcc ggccaggtca tcgcccagcg cattcccgcc cagggcgaga
    30661 acaattttct tactcatttt tcctcactca tcattcttga ttgtgtatag atccctgaca
    30721 gtggttagag cacgggaggg acaaacggtt tgcgtcgcag gaaacgacct cgcccggctt
    30781 tgcctgtaaa ggtgccgtca cagaaaatcg tttcaccacg ggataaggtt ctgacaatcg
    30841 cgccctgaca ggtaaaaccc tcccatggcg agtagtcggc gttgtcgtgg agatggcgat
    30901 gctgaatttg ttggctctga cgtgggtcga taatcaccac gtcgccatcg gaaccgggcg
    30961 ctaataatcc tttttgcggc cacaggccaa acagcctggc gggcattgcg ctggttaatt
    31021 caacaaagcg ttccggtgtt atacgtcccg tcatcacgcc actggaaaac agtaactgca
    31081 tgcggttttc cacaccgggt aagccatttg ggcagcgact gaaatcgcct ttagaaattt
    31141 gcaggcgttg agccatcgag aaggtgcagt gatcggtcgc caccacgtca atcgcaccat
    31201 cgctgatgcc acaccacagt ttgtcctgct cgcgtacgtt acgcagcggt gggctaagaa
    31261 tgaacttcat gccgtcttct gtatcgtaac tgcgttcgtc caacaggaga tattgtgggc
    31321 aggtttcaac ccagactggc tggtgattcg cacgggcaag acgcagataa tccagaccta
    31381 agccgttaga caggtgcacg atatagagcg gggcgttacc ggcaatttgt gccaggttaa
    31441 tcatgcgggc gatggcttcc gcttcgcatt ccagagggcg actcaaggca tgatagcgcg
    31501 gcgcggttaa ccctgcggcg ataaattccg cccgcttgct ggcgatagcc gcatcatttt
    31561 ccgggtgcac ggtggtcagc gcgccggatt catgcagacg gcgtaatgcc tgcaaaacct
    31621 cgtcatcgtt gagtttgtat tgataggtta aatagagttt aaaactgctc agtccttcct
    31681 cgaccatcat cgggatttcg tcgaggattg cgtgattaat gtgctggatc acaccgtgaa
    31741 agctgtaatc gatgaccgct ttatgggcgg cataaccacg ataaacctcc agttgatggc
    31801 gtaaccgaca gccgtttggg ccaaatccca tatggtcaat aatggttgtt gtaccgccac
    31861 acgcagctgc gcgggtaccg gtaaaaaaat catcacaact gcgcgcgatg ccgacatcaa
    31921 tattgaaatg cgtatggaca tccacgccgc cagggaaaac gtaacagcca gtggcatcaa
    31981 tttcttcata cgggagctgc ggcgaaatat tgttgcccaa ctggcgaaca atcccgcttt
    32041 caatcagcaa atcctgtttg gcttgtccat ctgcgttaac gacagtgccg tttttgatca
    32101 atacgcgcat agcaaactcc aaaaaccctc cggcgaaccg gaggggaata agtgaagagt
    32161 aattactctg ttgccagcca gcttaacggg attgcagcgt acatcgcggc acaggtcacc
    32221 aggtgagatt tccaggtttt ttcgttaggt gcatgcgctt caggttcttt acccgggcca
    32281 aagccgatca ccggaatgcc gtgacggccc atgatagata cgccgttagt tgagaaggtc
    32341 cacttatcaa caaccggcgc tttgccaaac agcccttcgt aggcattcac cagtgcttta
    32401 acggtgaagt gatcttcttc cactttccag gtcgggaagt agcattcggt tgggtaaacc
    32461 aggccagtcc aggacggacg gtcgtagttg tacatagaaa caaccgcgtt agctttctgt
    32521 actgcaggca gggcgcggat ttcgtccagc gcgccttccc aggtttcgcc ccaggtcaga
    32581 cggcggtcaa tagagacggc gcagctatct gctacagcgc aacggcttgg ggatgtgaag
    32641 aagatttcag aaacggtgag ggtgcctttg ccgaggaatt cgtcataacc cagacgttgg
    32701 gagagttctt gtaattcgcc aagaatcgga cccattttga aaatggcgtt gtcaccgcgt
    32761 tctggcgcag aaccgtggca gctaacaccc tgaacatcaa tacgaatttc catacgaccg
    32821 cgctgaccac ggtatacctg gcagtcggtt ggttcggtac tgaccacaaa ttccgggcga
    32881 atgccggatt gttcaataat gtactgccag cacagaccgt cgcagtcttc ttcctgcaca
    32941 gtaccggtaa ccagcagggt atattcatct tccagaccga ggtctttaat gattttaccg
    33001 gcataaacca tagatgccat gccgccttcc tggtcggaag taccgcgacc accgatcagc
    33061 tcatcagttt ccatgccttc gtacggatcg aagtcccagt ttttgatgtt gccaatgccg
    33121 acggtatcga tatgagcgtc cattgccacc agacgcgggc cgtggccgat ataaccgaga
    33181 acgttgccca tcgggtcgat ttcaacttta tcgaagccga ctttttccat ctcttcttta
    33241 atacgatgta ctacgcgttt ttcgtcgcag ctttcactgg gaatagcaac catgtcgcgc
    33301 aggaagcgag tcatgtccgc ctggtaatct tttgcttttt caagaatcag tttgaatgga
    33361 atattcttag ccattatttt tctccagatt ttttactccc cgttttgcag ggagtagttc
    33421 caatagggtg attaaggtgc tacagcgtgt ttgccttccc agacaacttc gcggtagtgc
    33481 ttcacgtcgg tgtcgccttc agtgctgata accagcacca cggcatcttt gttcagcgcc
    33541 agtttttcca tcaggctttg acgttgcggg tgataatgaa ccgctgcgag aacgcccaaa
    33601 ccgacagcgc cggattcacc ggagatgatg cgcgggtcgt tgccgtacgg attacccagc
    33661 acgcgcatac ctaatgcggc aacgctgtcc tggcaggaga tgaattgggt ggcgcagtta
    33721 cgtaggattt cccagcccag cgggttaggt tcgccacagg ccaggcccgc catgatggtg
    33781 gccatatcac cgccaacgtt gacgatgtcg cctttgacgc cggagcgata aatacagtca
    33841 gctttgtcag gttcaacaat aatgctgtgc agattttgcg ggctgtagac gtcgaccaga
    33901 taacccagca caccaccggc cattgctccg acaccggctt gcagcagaac gtgcgtcggg
    33961 gttacgccca tttcacgcat ttgctcgacg gcttcatctg ccagggttgc gtagccttgc
    34021 atgatccagg ttgggatttt ggtgtaacct tcccatgccg tgtcctgtac cacttcccag
    34081 ccgtgctgct gcgcgtgttg catggtcagg cgaacggtat cgtcatagtt catatccgtg
    34141 acgatgcact cggcaccgag gttcagaatg gcgtcaacgc gttcctgagc agaacctttc
    34201 ggcatgtaaa tcaccgcatt ctgtccgagt tgctgtgctg cccacgccac accgcgcccg
    34261 tggttgccgt cggtggtggt cgcgaaagtc attttttcgc cgatggcatt tttcaggtgc
    34321 tcaaatgaca gcgtttcgat atcaagatga tatttttcac acaataattg agcgatggcg
    34381 tacgcaccgc caagcatttt gaaggcgttc agaccgaatc gttttgattc gtctttgacg
    34441 agaattttct tcacaccaaa aaggtttgcg agatcgtcca gcgcacaaag cggtgttggg
    34501 cgataaccag ctattttctg gtggaactgg cgcgccagtt tggcctggct ttgcgaaaag
    34561 agcgatgatg tttcgccgtt gaaaaatttg ttatcggcga tatcaatctt caatgagaaa
    34621 acggacatat cctatccttt tggcctctgg aaatagaggg ccgaccagct gatcggcccg
    34681 aggggttatt tcacgcgttc ttgcgcttct ttcagcagtt gctcgagcag tgcacctggt
    34741 ttggcgtatt tacgggacag gatcatcgcg gcgatgatat aaggcttcca gctggcttct
    34801 ttgtaggtag cgatacggta tttttcgaat acgccttcag tcacttcccc ttctttgcag
    34861 gatacgccgc tgatatcagc tggcaggcag tgcatgtaca gggcttcgcc atcacgggtc
    34921 agttccatca tctcttcagt acaatgccag tctttgtgtt gcgcgttctg tgccagacac
    34981 tgtttttcca gtgcttttaa gccttcgtga tcgttagcgc gcagcaattc ggtacgctgt
    35041 tccatcactt tgtaaggtgc ccatgacttc ggataaacga tgtctgcatc tttgaatgct
    35101 tcttccatgc tggtgacctg acggaagcta ccgccagatg ctttagcatt gtttttcgcg
    35161 acttctacta catccgggat caggtcgtag ccttccggat gggccagggt gacatccata
    35221 ccgaagcgag tcatcagacc gatgatgcct tgtggtacag agagcggttt gccatagctt
    35281 ggagagtagg cccaggtcat ggcgattttt ttacctttca ggttttccag tgaaccaaag
    35341 tgttcacgta accacgcgag gtcagccatt gactgagtcg ggtggtcaat atcgcattgc
    35401 aggttcacta aagccggacg ctgtggcagt acaccctgct tgtaaccgtc atcaagtgca
    35461 gcgccaactt cacgcatata ggcgttgcct gcgcccagat acatatcgtc gcgaatacca
    35521 atagcgtcgg cgcagaagga gatcatattg gcggtttcac gcacggtttc gccgtgagcg
    35581 atttgtgatt tgccttcgtc gagatcttgt tgtgcaaggc cgagcaggtt aagcgcggaa
    35641 gcataagaga agcgggtacg agtggagttg tcgcggaata cggaaatacc taatccacta
    35701 ttaaagactt tggttgagat gttttcagca cgcagtgctt ttaatgctgc ggcaacgtcc
    35761 agtacttgtt tcagttcatc tggcgtctgt tcccacgtta acaaaaaatc tttctcgtga
    35821 aggtgagagg tcagcgaatt gatatcctta atcagctcat taacagtttt catcataaag
    35881 tcccggtagt ggaatgacag gcaaagtggt ttatttcact gtgacttgcc aaagtgattg
    35941 gtgttttcac agctatacct gggactaaca ataagtgtgc cagaattatc cacggggctg
    36001 taaaagacta atttgacgga taatgtgtgg ggttgatcac aaattgatgc cagcttcggg
    36061 ttgtttgtaa aatacgaaaa cgattggctt ttcttatcgc gttatttatt tactgctaag
    36121 tatcagaaat aagataaagg gacaggctat ctctcttcag tttgataaac tcaccgccgt
    36181 aattctcata ttgatataga aatgtgatat ctcttccata atttcattag aaagtgataa
    36241 aaatcttatg tttttatcaa agccaatttc gcctgagtta atatcatcat gatctgtgaa
    36301 ccatcaacgt cttcaatgat cgacttttaa gtaagtctgg aaggtaaagc tatggagctt
    36361 gctactacgc agtcagtatt gatgcaaatt caaccgacaa ttcagcgttt tgccagaatg
    36421 cttgccagcg ttttgcaggt tgagatcgtt gatgaaaact tgtgtcgcgt cgccggaact
    36481 ggcgcgtatg ggaagtttct tggccgccag ttgagcggca actcacgcct gctccgccac
    36541 gtcctggaaa cgaaaactga aaaagttgtg acacagtctc gcttcgatcc cctttgcgaa
    36601 ggttgcgata gtaaagaaaa ttgccgcgaa aaagcatttc tgggtacgcc tgtcatttta
    36661 caggatcgtt gtgttggggt gataagtttg attgccgtta cccacgagca acaagagcat
    36721 atcagtgata atttacgcga attttctgat tatgttcgcc atatatccac catttttgtt
    36781 tcgaaacttc tggaggatca ggggccagga gataacatca gtaaaatatt cgcgaccatg
    36841 atcgataata tggatcaggg cgtattagtt gttgatgatg aaagtcgggt tcagtttgtt
    36901 aatcagactg ccttaaaaac acttggtgtt gtacaaaata atattattgg gaaacctatc
    36961 cgtttcagac cattaacatt tgagagtaat tttactcatg gacatatgca gcatattgtt
    37021 tcgtgggacg ataaaagtga attaatcatt ggtcaattgc ataacattca gggccgacaa
    37081 ttatttttaa tggcatttca ccaatcgcat accagttttt ctgtagcaaa tgcacctgat
    37141 gaaccacata ttgaacaatt ggttggcgag tgccgtgtta tgcggcaatt aaaacgactc
    37201 attagccgta ttgcacccag cccatccagc gttatggtgg ttggtgaaag cggcacgggt
    37261 aaagaagtcg tcgcccgagc aatccataag ttgagcggaa gacggaataa accctttatt
    37321 gctatcaact gtgccgcgat tccggagcag cttctggaaa gcgaactgtt cggttatgtt
    37381 aaaggcgcat ttactggcgc ttctgccaac ggtaaaacag ggttgattca ggcggcgaat
    37441 acgggcacgc tgtttctcga tgaaataggt gatatgccat taatgttgca ggctaaatta
    37501 ctgcgcgcta ttgaggcgcg tgaaattctg ccgattggtg ccagtagccc aatacaagtc
    37561 gacattcgca tcatttctgc aactaatcag aatttggccc agttcattgc cgaaggtaaa
    37621 ttccgcgaag atctcttcta ccgacttaat gttatcccga taactctgcc accgctgcgt
    37681 gaacgtcagg aagatattga actattggtg cattactttt tacatctgca tacccgtcgt
    37741 ctgggatcgg tttatcctgg cattgctccc gatgtcgtcg aaatattgcg taagcatcgt
    37801 tggcccggaa acctgcgcga gttaagcaat ttgatggaat atctggttaa cgtagttcct
    37861 tcaggtgaag ttatcgacag cacgctattg ccgccaaatc tgctgaataa tggcacaacg
    37921 gagcaaagtg atgtaacaga ggtcagtgag gcgcacctgt cactcgatga tgcgggcggc
    37981 acggcgctgg aggagatgga aaagcaaatg atccgcgagg cgctttcacg tcataacagc
    38041 aagaagcaag ttgctgatga actgggcatc ggcattgcta cgctctatcg caagattaag
    38101 aaatatgagt tgttaaacac ataacctcag tgaatccggc ctgaattcag gccggatatc
    38161 cttttacttc gttttctcgc aatccagaac tgtatttaca atcatctgat accccgtgca
    38221 gcgacaaaga tttcccgcca gtccgcgacg aatttccgta atggttaatg gcttctcgcg
    38281 tggtttcgcc agcattgccg tggtagcc
//
LOCUS       DAZUDJ010000046        38087 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.046, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000046 DAZUDJ010000000
VERSION     DAZUDJ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38087
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.046"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(10..1368)
                     /gene="dgcT"
                     /locus_tag="ACHY1N_003076"
     CDS             complement(10..1368)
                     /gene="dgcT"
                     /locus_tag="ACHY1N_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HFS4045355.1"
                     /translation="MEKDYLRISSTVLVSLLFGLALVLVNSWFNQPGVEEVVPRSTYL
                     MVMIALFFIDTVAFIFMQLYFIYDRRQFSNCILSLAFLSCLIYFVKTVIIIQQIIEGR
                     LTSSVVQNDIAIYYLFRQMSLCILIFLALVNKVSENTKQRNLFSKKMTLCISLFFVFW
                     GPIVAHILSSHYESYNLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNGLRY
                     DIWNGVTVIAFCAVLYNISLLFMSRYSVSTWYISRTIEVVSKLTVMVIFMCHIFSALR
                     VTKNIAHRDPLTNIFNRNYFFNELTVQSASAKKTPYCVMIMDIDHFKKVNDTWGHPVG
                     DQVIKTVVNIIGKSIRPDDLLARVGGEEFGVLLTDIDTERAKALAERIRENVERLTGD
                     NPEYAIPQKVTISIGAVVTQENALNPNEIYRLADNALYEAKETGRNKVVVRDVVNFCE
                     SP"
     gene            1955..4378
                     /gene="pgaA"
                     /locus_tag="ACHY1N_003077"
     CDS             1955..4378
                     /gene="pgaA"
                     /locus_tag="ACHY1N_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1901515 -
                     poly-beta-1,6-N-acetyl-D-glucosamine transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine export
                     porin PgaA"
                     /protein_id="HFS4045356.1"
                     /translation="MYSSSRKRCPKTKWALKLLTAAFLAASPAAKSAVNNAYDALIIE
                     ARKGNTQPALSWFALKSALSNNQIADWLQIALWAGQDKQVITVYNRYRHQQLPARGYA
                     AVAVAYRNLQQWQNSLTLWQKALSLEPQNKDYQRGQILTLADAGHYDTALVKLKQLNS
                     GAPDKANLLAEAYIYKLAGRHQDELRAMTESLPENASTQQYPTEYVQALRNNQLAAAI
                     DDANLTPDIRADIHAELVRLSFMPTRSESERYAIADRALAQYAALEILWHDNPDRTAQ
                     YQRIQVDHLGALLTRDRYKDVISHYQRLKKTGQIIPPWGQYWVASAYLKDHQPKKAQS
                     IMTELFYHKETIAPDLSDEELADLFYSHLESENYPGALTVTQHTINTSPPFLRLMGTP
                     TSIPNDTWLQGHSFLSTVAKYSNDLPQAEMTARELAYNAPGNQGLRIDYASVLQARGW
                     PRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQAAVLTHDVVEREPQDPGVVRL
                     KRAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYSPPLKDNWRGFAGFGYADG
                     QFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDNWRIGS
                     QLERLSHRVPLRAMKNGVTGNSAQAYVRWYQNERRKYGVSWAFTDFSDSNQRHEVSLE
                     GQERIWSSPYLIVDFLPSLYYEQNTEHDTPYYNPIKTFDIVPAFEASHLLWRSYENSW
                     EQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGATLRWEKRPYDGDREHNLY
                     VEFDMTFRF"
     gene            4387..6405
                     /gene="pgaB"
                     /locus_tag="ACHY1N_003078"
     CDS             4387..6405
                     /gene="pgaB"
                     /locus_tag="ACHY1N_003078"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     N-deacetylase PgaB"
                     /protein_id="HFS4045357.1"
                     /translation="MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPW
                     PHNGFVAISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGK
                     PLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVD
                     REYFATWQQVREVARSRLVELASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYET
                     AAEYRERIRLDAVKMTEYLRTKVEVNPHVFVWPYGEANGIAIEELKKLGYDMFFTLES
                     GLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKSPQRIMHIDLDYVYDENLQQMDR
                     NIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTR
                     SGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYHRLSPFDDRVRAQVGMLY
                     EDLAGHAAFDGILFHDDALLSDYEDASAPAITAYQQAGFSGSLSEIRQNPEQFKQWAR
                     FKSRALTDFTLELSARVKAIRGPHIKTARNIFALPVIQPESEAWFAQNYADFLKSYDW
                     TAIMAMPYLEGVAEKSADQWLIQLTNQIKNIPQAKDKSILELQAQNWQKNGQHQAISS
                     QQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDLIRPEFSTAWYPKND"
     gene            6398..7723
                     /gene="pgaC"
                     /locus_tag="ACHY1N_003079"
     CDS             6398..7723
                     /gene="pgaC"
                     /locus_tag="ACHY1N_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008375 - acetylglucosaminyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042710 - biofilm formation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine synthase"
                     /protein_id="HFS4045358.1"
                     /translation="MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIM
                     WIVGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRY
                     ENIEVIAVNDGSTDKTRAILDRMAAQIPHLRVIHLAQNQGKAIALKTGAAAAKSEYLV
                     CIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIK
                     RTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRA
                     LCWILMPETLKGLWKQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAF
                     TCLVGFIIYAVQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLMIENRYEHNLT
                     SSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG"
     gene            7725..8138
                     /gene="pgaD"
                     /locus_tag="ACHY1N_003080"
     CDS             7725..8138
                     /gene="pgaD"
                     /locus_tag="ACHY1N_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     biosynthesis protein PgaD"
                     /protein_id="HFS4045359.1"
                     /translation="MNNLIITTRQSPVRLLVDYVATTILWTLFALFIFLFAMDLLTGY
                     YWQSEARSRLQFYFLLAVANAVVLIVWALYNKLRFQKQQHHAAYQYTPQEYAESLAIP
                     DELYQQLQKSHRMSVHFTSQGQIKMVVSEKALVRA"
     gene            complement(8188..8976)
                     /gene="phoH"
                     /locus_tag="ACHY1N_003081"
                     /pseudo
     CDS             complement(8188..8976)
                     /gene="phoH"
                     /locus_tag="ACHY1N_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741490.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
     gene            complement(9595..10866)
                     /gene="efeB"
                     /locus_tag="ACHY1N_003082"
     CDS             complement(9595..10866)
                     /gene="efeB"
                     /locus_tag="ACHY1N_003082"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0033212 - iron import into cell [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake transporter
                     deferrochelatase/peroxidase subunit"
                     /protein_id="HFS4045360.1"
                     /translation="MQYEDKNGVNEPSRRRLLKGIGALALAGSCPVAHAQKTQSAPGT
                     LSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKPDLERLFRLLTQRFAFLT
                     QGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKM
                     TRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHA
                     ARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQ
                     FRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLAN
                     PRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALE
                     EYVKPIGGGYFFALPGVKDANDYLGSALLRV"
     gene            complement(10872..11999)
                     /gene="efeO"
                     /locus_tag="ACHY1N_003083"
     CDS             complement(10872..11999)
                     /gene="efeO"
                     /locus_tag="ACHY1N_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HFS4045361.1"
                     /translation="MTINFRRNALQLSVAALFSSAFMANAANVPQVKVTVTDKQCEPM
                     TITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMT
                     CGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDA
                     IKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHR
                     LEKALFGDNTTKGMDQYADQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKI
                     SGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKY
                     RTKDGFETYDKLTDADRNALKGPITALAEDLAQLRGVLGLD"
     gene            complement(12057..12887)
                     /gene="efeU"
                     /locus_tag="ACHY1N_003084"
     CDS             complement(12057..12887)
                     /gene="efeU"
                     /locus_tag="ACHY1N_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033573 - high-affinity iron permease
                     complex [Evidence IEA];
                     GO_function: GO:0005381 - iron ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034755 - iron ion transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake transporter permease EfeU"
                     /protein_id="HFS4045362.1"
                     /translation="MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLL
                     AAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLE
                     QAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLAT
                     AVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFD
                     MSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA
                     "
     gene            12923..13225
                     /locus_tag="ACHY1N_003085"
     CDS             12923..13225
                     /locus_tag="ACHY1N_003085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045363.1"
                     /translation="MQRKVNRSDSDYHYGKEKYKRNVYKMMLECKQREVMPRDINDYS
                     RVERWDCLQRTMCSCRMPRKRRIQPTKLSRLNASELPCKTDKRVYQAISSIRDYQI"
     gene            complement(13430..14938)
                     /gene="putP"
                     /locus_tag="ACHY1N_003086"
     CDS             complement(13430..14938)
                     /gene="putP"
                     /locus_tag="ACHY1N_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005298 - proline:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0031402 - sodium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0015824 - proline transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HFS4045364.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     YNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKHASQKELVWVGRVMVLVVALVAIALAAN
                     PENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWL
                     GLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQES"
     gene            complement(15097..15306)
                     /locus_tag="ACHY1N_003087"
     CDS             complement(15097..15306)
                     /locus_tag="ACHY1N_003087"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045365.1"
                     /translation="MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKINQTFSLRQ
                     LTFLKGATAKNVRECNLMKNSVAEH"
     gene            15361..19323
                     /gene="putA"
                     /locus_tag="ACHY1N_003088"
     CDS             15361..19323
                     /gene="putA"
                     /locus_tag="ACHY1N_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0003842 - 1-pyrroline-5-carboxylate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0004657 - proline dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HFS4045366.1"
                     /translation="MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQL
                     ENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRP
                     ETEAVSMLLEQARLPQPVAAQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGK
                     LVSTHNEAILSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLARRLLENGANTSF
                     VNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDL
                     ANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPR
                     EVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGS
                     TEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAG
                     QRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYN
                     RNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNAL
                     REWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDAL
                     TQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDS
                     DQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            complement(19363..20001)
                     /gene="rutR"
                     /locus_tag="ACHY1N_003089"
     CDS             complement(19363..20001)
                     /gene="rutR"
                     /locus_tag="ACHY1N_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HFS4045367.1"
                     /translation="MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQI
                     AELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQ
                     HLIFMIWASTQHYADFAPQVEAVTGATLRDEIFFNQTVENVQRIIIEGIRPR"
     gene            20289..21380
                     /gene="rutA"
                     /locus_tag="ACHY1N_003090"
     CDS             20289..21380
                     /gene="rutA"
                     /locus_tag="ACHY1N_003090"
                     /EC_number="1.14.99.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309285.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein A"
                     /protein_id="HFS4045368.1"
                     /translation="MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDF
                     ALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAA
                     TIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKS
                     DFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFA
                     PTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQ
                     KDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDF
                     LSGIETFGERIQPLMQCRAHLPALTQEVA"
     gene            21380..22072
                     /gene="rutB"
                     /locus_tag="ACHY1N_003091"
     CDS             21380..22072
                     /gene="rutB"
                     /locus_tag="ACHY1N_003091"
                     /EC_number="3.5.1.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxyureidoacrylate/ureidoacrylate
                     amidohydrolase RutB"
                     /protein_id="HFS4045369.1"
                     /translation="MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVS
                     TTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRNQP
                     QLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTG
                     IATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFC
                     DALSPTSFARIA"
     gene            22084..22470
                     /gene="rutC"
                     /locus_tag="ACHY1N_003092"
     CDS             22084..22470
                     /gene="rutC"
                     /locus_tag="ACHY1N_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-aminoacrylate deaminase"
                     /protein_id="HFS4045370.1"
                     /translation="MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLF
                     ADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKP
                     ARFCIQCGLVKPDALVEIATIAHIAK"
     gene            22478..23278
                     /gene="rutD"
                     /locus_tag="ACHY1N_003093"
     CDS             22478..23278
                     /gene="rutD"
                     /locus_tag="ACHY1N_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA];
                     GO_process: GO:0006212 - uracil catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein D"
                     /protein_id="HFS4045371.1"
                     /translation="MKLSLSPPPYADAPVVVLISGLGGSGSYWLQQLAVLEQEYQVVC
                     YDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYP
                     ASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPR
                     LEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSS
                     ELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL"
     gene            23288..23878
                     /gene="rutE"
                     /locus_tag="ACHY1N_003094"
     CDS             23288..23878
                     /gene="rutE"
                     /locus_tag="ACHY1N_003094"
                     /EC_number="1.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonic semialdehyde reductase"
                     /protein_id="HFS4045372.1"
                     /translation="MNEAVSPGALSTLFTDARTHNGWRETPVSDETLRELYALMKWGP
                     TSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFP
                     HSDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFA
                     GSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL"
     gene            23889..24383
                     /gene="rutF"
                     /locus_tag="ACHY1N_003095"
     CDS             23889..24383
                     /gene="rutF"
                     /locus_tag="ACHY1N_003095"
                     /EC_number="1.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309280.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent FMN reductase RutF"
                     /protein_id="HFS4045373.1"
                     /translation="MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTD
                     TPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQT
                     GVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALM
                     RPAC"
     gene            24404..25732
                     /gene="rutG"
                     /locus_tag="ACHY1N_003096"
     CDS             24404..25732
                     /gene="rutG"
                     /locus_tag="ACHY1N_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015218 - pyrimidine nucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006864 - pyrimidine nucleotide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization transport protein G"
                     /protein_id="HFS4045374.1"
                     /translation="MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMF
                     GATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNG
                     QGMNPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
                     IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLG
                     LGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGR
                     NMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAML
                     LGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTL
                     VLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP"
     gene            complement(25815..25988)
                     /gene="ymdF"
                     /locus_tag="ACHY1N_003097"
     CDS             complement(25815..25988)
                     /gene="ymdF"
                     /locus_tag="ACHY1N_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415525.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HFS4045375.1"
                     /translation="MANHRGGSGNFAEDRERASEAGKKGGQHSGGNFKNDPQRASEAG
                     KKGGKSSHGKSDN"
     gene            26361..26957
                     /gene="wrbA"
                     /locus_tag="ACHY1N_003098"
     CDS             26361..26957
                     /gene="wrbA"
                     /locus_tag="ACHY1N_003098"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003955 - NAD(P)H dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HFS4045376.1"
                     /translation="MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMP
                     PQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
     gene            26978..27205
                     /gene="yccJ"
                     /locus_tag="ACHY1N_003099"
     CDS             26978..27205
                     /gene="yccJ"
                     /locus_tag="ACHY1N_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccJ family protein"
                     /protein_id="HFS4045377.1"
                     /translation="MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWE
                     EGSDEVLVKAFAKTDKDSLFWGEQTIERKNV"
     gene            complement(27243..28484)
                     /gene="agp"
                     /locus_tag="ACHY1N_003100"
     CDS             complement(27243..28484)
                     /gene="agp"
                     /locus_tag="ACHY1N_003100"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HFS4045378.1"
                     /translation="MNKTLIAAAVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRA
                     PLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECP
                     PPYTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     SEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQE
                     PGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTS
                     PEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNE
                     RTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCP
                     IDANGFCPMDKFDSVLNEAVK"
     gene            complement(28777..30033)
                     /gene="yccE"
                     /locus_tag="ACHY1N_003101"
                     /pseudo
     CDS             complement(28777..30033)
                     /gene="yccE"
                     /locus_tag="ACHY1N_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415521.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YccE family protein"
     gene            30294..31214
                     /gene="cbpA"
                     /locus_tag="ACHY1N_003102"
     CDS             30294..31214
                     /gene="cbpA"
                     /locus_tag="ACHY1N_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HFS4045379.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIF
                     GQHARQSRQRPAARGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
                     NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVS
                     PWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMP
                     PKPDENTAALWQQLADAQSSFDPRKDWGKA"
     gene            31214..31519
                     /gene="cbpM"
                     /locus_tag="ACHY1N_003103"
     CDS             31214..31519
                     /gene="cbpM"
                     /locus_tag="ACHY1N_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HFS4045380.1"
                     /translation="MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWV
                     FDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP"
     gene            complement(31612..32211)
                     /gene="torD"
                     /locus_tag="ACHY1N_003104"
     CDS             complement(31612..32211)
                     /gene="torD"
                     /locus_tag="ACHY1N_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051259 - protein complex oligomerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HFS4045381.1"
                     /translation="MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLL
                     KSEPPLAAAVNELENCIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQ
                     EIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTA
                     LWQWLPEFAARCHQYDSFGFYAALSQLLLVLVECDHQNR"
     gene            complement(32208..34754)
                     /gene="torA"
                     /locus_tag="ACHY1N_003105"
     CDS             complement(32208..34754)
                     /gene="torA"
                     /locus_tag="ACHY1N_003105"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_function: GO:0050626 - trimethylamine-N-oxide reductase
                     (cytochrome c) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HFS4045382.1"
                     /translation="MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAAT
                     DAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
                     QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTH
                     EYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYCVGFEQFLPYLLGEK
                     DGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLA
                     AMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIP
                     IARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGVIAMKQVVPPQFEARNDFDI
                     FRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGG
                     PGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDV
                     VRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIG
                     TSQLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEYVPASQVKS"
     gene            complement(34754..35926)
                     /gene="torC"
                     /locus_tag="ACHY1N_003106"
     CDS             complement(34754..35926)
                     /gene="torC"
                     /locus_tag="ACHY1N_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HFS4045383.1"
                     /translation="MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTST
                     TEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
                     KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAK
                     GDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGD
                     VQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHG
                     APEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK"
     gene            36056..36748
                     /gene="torR"
                     /locus_tag="ACHY1N_003107"
     CDS             36056..36748
                     /gene="torR"
                     /locus_tag="ACHY1N_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
                     /protein_id="HFS4045384.1"
                     /translation="MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQN
                     QPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTK
                     PLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTR
                     AEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQ
                     HGEGYFLAADVC"
     gene            complement(36721..37749)
                     /gene="torT"
                     /locus_tag="ACHY1N_003108"
     CDS             complement(36721..37749)
                     /gene="torT"
                     /locus_tag="ACHY1N_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HFS4045385.1"
                     /translation="MRVLLFLLLSLFMLSAFSADNLLRWHDAQHYTVQASTPLKAKRA
                     WKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWG
                     AEAILLGSSTTSFPDLQKQVANLPVIELVNALDDPLVKSRVGVPWFQMGYQPGRYLVQ
                     WAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQE
                     MLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASD
                     QMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIRRSLSPGGFRPVYFY
                     QHTSAAKK"
BASE COUNT         9471 a         9834 c         9336 g         9446 t
ORIGIN      
        1 aatgccgctt tatggtgact cacaaaaatt caccacatcc ctcacaacca ccttattacg
       61 cccggtctct ttcgcctcgt aaagtgcgtt atcagccagt cgatagatct cattcgggtt
      121 taacgcattt tcctgagtca caacagcgcc aatactaatc gtcacttttt gtggtatagc
      181 gtattcagga ttatcgccag ttaaacgctc aacattttcc cgaatccttt ccgctaaagc
      241 tttcgcacgt tcagtatcga tgtccgtcag caagacgcca aactcttcgc cgccgacgcg
      301 cgctaaaagg tcatctggtc gtatgctttt cccaatgata ttcaccactg tttttatcac
      361 ctgatcgcca accggatgcc cccaggtgtc gttgactttt ttgaagtggt cgatatccat
      421 aatcatgacg caataaggcg tttttttggc tgatgctgat tgaactgtca gttcattaaa
      481 aaaataattt ctgttaaata tattggttaa gggatcgcga tgtgcaatgt tctttgttac
      541 tcgtagcgca ctgaatatat ggcacataaa tattaccata acggttaact tactgactac
      601 ttcaatagtg cgactaatat accaagtgga cacgctatac ctactcataa ataacagaga
      661 gatattgtac agtacggcac aaaaagcaat caccgtcact ccattccaga tatcatagcg
      721 taaaccatta aagtatagat taaccgaaag caaggttaac cacatgaaaa tcattatggt
      781 aacatatgag gctttccaaa ccacctgacc attttcattg gttaactcgg caatgtgtaa
      841 attgtagctc tcataatgac tagaaagtat gtgagcaact atcggccccc aaaaaacaaa
      901 aaacaaactt atgcacaaag tcattttttt ggaaaataaa ttgcgctgtt ttgtgttttc
      961 actaacttta ttcaccaatg ccagaaatat taatatgcac aaactcatct gacgaaacaa
     1021 ataatagatt gcaatgtcat tttggacaac actgcttgtc aaacgcccct caataatttg
     1081 ctgaatgata atgacggttt taacaaagta aatcaaacaa ctcagaaaag ccaaactaag
     1141 tatacagttt gaaaattgcc tacggtcata aatgaaatac aactgcataa aaataaatgc
     1201 aacagtatcg ataaaaaata aagcaatcat taccatcaga taggttgatc gtggaacaac
     1261 ttcctcaacg cctggctgat taaaccaact attcaccaaa accaaagcaa gcccaaacaa
     1321 taagctcact aatacagtac tactaattct caaatagtct ttttccataa agctacacca
     1381 atctgtaggt tgtagatccc tttctattat taatagatat aagaactgta ctgttgtcaa
     1441 tatgaaattc cgcccacaaa caataccgat aatgatagtt gctgaatgta attattattg
     1501 cctaagtgct ttatacattg tttgcaacaa gccaggcttg aaaatactta taaatggtta
     1561 tagaaaatcc ttataaaaca ttaattcata gatacattag gaataacaat taaatccgtg
     1621 agtgccgtag cgcagccttt catcaggact ttcgaaaaat ccgaaatcat gcatcggaat
     1681 ttactgattt aattatttta atcctaattt attttgaaaa aggcattggg atttatgccg
     1741 tattcctgaa gatcctcatc attggaatgg attttcgggc gagaaaagga ttttatatgg
     1801 acactctgct catcatttct tcttctcatc atcaacaatt cacgtctctc ttccgcgttt
     1861 aataacggat tatgaggtgc aaaaatatct ttcttttcag ttacctgtaa ttagatacag
     1921 agagagattt tggcaataca tggagtaata caggatgtat tcaagtagca gaaaaaggtg
     1981 cccgaaaacc aaatgggctt tgaaacttct tactgccgca tttttagcag cgagtcccgc
     2041 ggcgaagagt gctgttaata acgcctatga tgcattgatt attgaagctc gcaagggtaa
     2101 tactcagcca gctttgtcat ggtttgcact aaaatcagca ctcagcaata accaaattgc
     2161 tgactggtta cagattgcct tatgggccgg gcaagataaa caggttatta ccgtttacaa
     2221 ccgctaccgt catcagcaat taccagcgcg tggttatgca gctgtcgccg tcgcttatcg
     2281 taacctgcaa caatggcaaa actcgcttac actgtggcaa aaggcgctct ctctggagcc
     2341 gcaaaataag gattatcaac ggggacaaat tttaaccctg gcagatgctg gtcactatga
     2401 tactgcgctg gttaaactta agcagcttaa ctctggagca ccggacaaag ccaatttact
     2461 cgcagaagcc tatatctata aactggcggg gcgtcatcag gatgaattac gggcgatgac
     2521 agagtcatta cctgaaaatg catctacgca acaatatccc acagaatacg tgcaggcatt
     2581 acgtaataat caacttgctg ccgcgattga cgatgccaat ttaacgccag atattcgcgc
     2641 tgatattcat gccgaactgg tcagactgtc gtttatgcct acgcgcagtg aaagtgaacg
     2701 ttatgccatt gccgatcgcg ccctcgccca atacgctgca ttagaaattc tgtggcacga
     2761 taacccagac cgtactgccc agtaccagcg tattcaggtt gatcatcttg gcgcgttatt
     2821 aactcgcgat cgttataaag acgttatttc tcactatcag cgattaaaaa agacggggca
     2881 aattattccg ccctgggggc aatattgggt tgcatcggct tatctcaaag atcatcagcc
     2941 gaaaaaagca cagtcaataa tgaccgagct cttttatcac aaggagacca ttgccccgga
     3001 tttatccgat gaagaacttg cggatctctt ttacagccac ctggagagtg aaaattatcc
     3061 gggcgcgcta actgtcaccc aacataccat taatacttcg ccgcctttcc ttcggttaat
     3121 gggcacgcct acgagcatcc cgaatgatac ctggttacag gggcattcgt ttctctcaac
     3181 cgtagcaaaa tatagtaatg atcttcctca ggctgaaatg acagccagag agcttgctta
     3241 taacgcacca ggaaatcagg gactgcgcat tgattacgcg agtgtgttac aagcccgcgg
     3301 ttggcctcgt gcagcagaaa atgaattaaa aaaagcagaa gtgatcgagc cacgtaatat
     3361 taatctggag gttgaacaag cctggacagc attaacgtta caagaatggc agcaggcagc
     3421 tgtcttaacg cacgatgttg tcgaacgtga accgcaagat cccggcgttg tacgattaaa
     3481 acgtgcggtt gatgtacata atcttgcaga gcttcgtatc gctggctcaa caggaattga
     3541 tgccgaaggc ccggatagtg gtaaacatga tgtcgactta accaccatcg tttattcacc
     3601 accgctgaag gataactggc gcggttttgc tggattcggt tatgccgatg gacaatttag
     3661 cgaaggaaaa gggattgttc gcgactggct tgcgggtgtt gagtggcggt cacgtaatat
     3721 ctggctcgag gcagagtacg ctgaacgcgt tttcaatcat gagcataaac ccggcgcgcg
     3781 cctgtctggc tggtatgatt ttaatgataa ctggcgtatt ggttcgcaac tggaacgcct
     3841 ctctcaccgc gttccattac gggcaatgaa aaatggtgtt acaggcaaca gtgctcaggc
     3901 ttatgttcgc tggtatcaaa atgagcggcg taagtacggt gtctcctggg ctttcactga
     3961 tttttccgac agtaaccagc gtcatgaagt ctcacttgag ggtcaggaac gcatctggtc
     4021 ttcaccatat ttgattgtcg atttcctacc cagtctgtat tacgaacaaa atacagaaca
     4081 cgatacccca tactacaacc ctataaaaac gttcgatatt gttccggcat ttgaggcaag
     4141 ccatttgtta tggcgaagct atgaaaatag ctgggagcaa atattcagcg caggtgttgg
     4201 tgcctcctgg caaaaacatt atggcacgga tgtcgtcacc caactcggct acgggcaacg
     4261 cattagctgg aatgacgtga ttgatgctgg cgcaacgcta cgctgggaaa aacgacctta
     4321 tgacggtgac agagaacaca acttatacgt tgaattcgat atgacattca gattttaagg
     4381 ataaatatgt tacgtaatgg aaataaatat ctcctgatgc tggtgagtat aattatgctc
     4441 accgcgtgca ttagccagtc aagaacatca tttataccgc cacaggatcg cgaatcttta
     4501 ctcgccgagc aaccgtggcc gcataatggt tttgtagcga tttcatggca taacgttgaa
     4561 gacgaagctg ccgaccagcg ttttatgtca gtgcggacat cagcactgcg tgaacaattt
     4621 gcctggctgc gcgagaacgg ttatcaaccg gtcagtattg ctcaaattcg tgaagcacat
     4681 cgaggaggaa aaccgctacc ggaaaaagct gtagtgctga cttttgatga cggctaccag
     4741 agtttttata cccgcgtctt cccaattctt caggccttcc agtggcctgc tgtatgggcc
     4801 cccgtcggca gttgggtcga tacgccagcg gataaacaag taaaatttgg cgatgagttg
     4861 gtcgatcgag aatattttgc cacgtggcaa caagtgcgag aagttgcgcg ttcccgactc
     4921 gttgagctcg cttctcatac atggaattct cactacggta ttcaggctaa tgccaccggc
     4981 agcttattgc ctgtatatgt aaatcgtgca tattttactg accacgcacg gtatgaaacc
     5041 gcagcagaat accgggaaag aattcgtctg gatgctgtaa aaatgacgga atacctgcgt
     5101 acaaaggttg aggtaaatcc acacgttttt gtttggcctt atggcgaagc gaatggcata
     5161 gcgatagagg aattaaaaaa actcggttat gacatgttct tcacccttga atcaggtttg
     5221 gcaaatgcgt cgcaattgga ttccattccg cgggtattaa tcgccaataa tccctcatta
     5281 aaagagtttg cccagcaaat tattaccgta caggaaaaat caccacaacg gataatgcat
     5341 atcgatcttg attacgttta tgacgaaaac ctccagcaaa tggatcgcaa tattgatgtg
     5401 ctaattcagc gggtgaaaga tatgcaaata tcaaccgtgt atttgcaggc atttgctgat
     5461 cccgatggtg atgggctggt caaagaggtc tggtttccaa atcgtttgct accaatgaaa
     5521 gcagatattt ttagtcgggt tgcctggcaa ttacgtaccc gctcaggtgt aaacatctat
     5581 gcgtggatgc cggtattaag ctgggattta gatcccacat taacgcgagt aaaatactta
     5641 ccaacagggg agaaaaaagc acaaattcat cctgaacaat atcaccgtct ctctcctttc
     5701 gatgacagag tcagagcaca agttggcatg ttatatgaag atcttgccgg acatgctgct
     5761 tttgatggca tattgttcca cgatgatgct ttgctttcag attatgaaga tgccagtgca
     5821 ccggctatca cggcttatca gcaagcaggc tttagcggga gtctgagcga aattcgacaa
     5881 aacccggagc aatttaaaca gtgggcccgc tttaaaagtc gtgcgttaac tgacttcact
     5941 ttagaactta gtgcgcgcgt aaaagccatt cgcggtccac atattaaaac tgcacgaaat
     6001 atttttgcac ttccggtaat acaacctgaa agtgaagcct ggtttgcaca gaattatgct
     6061 gatttcctaa aaagctatga ctggaccgct attatggcta tgccttatct ggaaggtgtc
     6121 gcagaaaaat cggctgacca atggttaata caattgacca atcaaattaa aaacatccct
     6181 caggctaaag acaaatctat tttagaatta caggcacaaa actggcagaa aaatggtcag
     6241 catcaggcta tttcttcgca acaactcgct cactggatga gcctattaca actgaatgga
     6301 gtgaaaaact atggttatta tcccgacaat tttctgcata accaacctga aatagacctt
     6361 attcgtcctg agttttcaac agcctggtat ccgaaaaatg attaatcgca tcgtatcgtt
     6421 ttttatatta tgtctggtgt tatgcatacc cctatgcgta gcgtactttc actctggtga
     6481 actgatgatg aggttcgttt tcttctggcc gttttttatg tccattatgt ggattgttgg
     6541 cggcgtctat ttctgggtct atcgtgaacg ccactggccg tggggagaaa acgcaccagc
     6601 tccccagttg aaagataatc cgtctatctc cattatcatt ccctgtttta atgaggagaa
     6661 aaacgttgag gaaaccatac acgccgcttt agcacagcgt tatgagaaca ttgaagttat
     6721 tgccgtaaat gacggttcaa cagataaaac ccgtgccatc ctggatcgca tggctgcaca
     6781 aattccccat ttgcgggtca ttcatctggc gcaaaaccag gggaaagcca ttgcgcttaa
     6841 aaccggagct gccgcggcga aaagtgaata tctggtgtgc attgatggcg atgcgttatt
     6901 agaccgcgat gcggcggcat atattgtgga accgatgttg tacaacccgc gtgtgggtgc
     6961 cgtaaccggt aatcctcgta ttcgaacacg ttctaccctg gtgggtaaaa ttcaggttgg
     7021 cgagtattcc tcaattattg gtttgatcaa gcgaacccag cgtatctatg gaaacgtatt
     7081 taccgtttcc ggtgttattg ccgcatttcg tcgcagcgcc ctggcagaag tgggttactg
     7141 gagtgacgat atgatcaccg aagatattga tattagctgg aagctgcagt tgaatcagtg
     7201 gacgattttt tacgagccac gggcgctgtg ctggatatta atgcctgaaa cgttaaaagg
     7261 gctgtggaaa cagcgcctgc gctgggctca gggcggtgca gaagtattcc tcaaaaatat
     7321 gacaaggttg tggcgcaaag aaaactttcg aatgtggccg ctgttttttg aatactgcct
     7381 gacgacaata tgggccttca cctgcctggt cggtttcatt atttacgcag tccaacttgc
     7441 cggtgtaccg ttaaatattg aattgacaca tatcgctgcg acacatactg ccggaatatt
     7501 attgtgtacg ttatgtttac tgcaatttat tgtcagcctg atgatcgaga atcgctatga
     7561 gcataatctg acttcatcgc ttttctggat tatttggttc ccggttattt tctggatgct
     7621 gagcctggca acgacattgg tatcatttac acgagtcatg ttgatgccta aaaagcaacg
     7681 cgcccgttgg gtaagtcccg atcgcgggat tctgagaggt taatatgaac aatttaatta
     7741 ttacgacccg acaatcacca gtacgtttac tggttgatta tgttgccaca accatcttgt
     7801 ggacattatt tgcgttgttc atattcttat tcgccatgga tctgctgacg ggttattact
     7861 ggcaaagcga ggccagaagc cgacttcagt tctatttttt gctggcagtg gcgaatgccg
     7921 tcgtgttaat tgtctgggcg ctgtacaata agctgcgttt tcaaaaacag cagcatcatg
     7981 cagcctacca atatacgccg caagaatatg cagagagctt agcaatacct gatgagctct
     8041 atcagcaact acaaaaaagc cacaggatga gcgtacactt caccagccag gggcaaataa
     8101 aaatggttgt ttcagaaaaa gcgctagtcc gggcataaac acccaaaaca aagcccggtt
     8161 cgcccgggct ctgcaccgat aatacactta actgtatgca tgctgcgtac gttggcaaag
     8221 tgccgaacgt acgcagtcct ctttaccgaa ccggacgatc ccaaccattt catcttcttc
     8281 gaaacgttcc agcgcgtcac ttaatccgga gcacacgccg cgaggcaaat cgcattgcgt
     8341 gatatcaccg ttgacgataa ccgtcacgtt ctccccgagg cgggttaaaa acattttcat
     8401 ttgcgcggca gtcacattct gcgcctcgtc aagaatgacg actgcatttt caaaggtacg
     8461 tccacgcata taggcgaacg gcgcaatttc caccttccct atttccggtc gcaggcagta
     8521 ctgcataaag gaagccccta agcgccggac cagcacgtcg tagaccgggc gaaaataggg
     8581 agcaaacttt tctgcgatat ctccaggtaa gaagccaaga tcttcatcgg cttgcagaac
     8641 tggacgggtg acgataatcc tgtcgacatc cttatgtatc agggcctctg ccgcttttgc
     8701 tgcgctgatc caggtttttc cgcacccggc ttcgcccgtg gcgaatatca actgcttact
     8761 ctcaatagcc ttcagatagt gcaattgcgc ttcatttcgc gcgaggatgg gcgaagtatc
     8821 gcgactgtcg cgggccatac caatggcttc tacgccgccc atctgcacaa gcgaggtgac
     8881 ctattcttct tcacgctgct tatggctgcg cgaatcccgt ctcagcacac gttttgcctc
     8941 acgacgagct ttgatcactg ctttttgtct tcccatggag agcaccttga gttgtttgta
     9001 ttcatcacac gcgccgttgg cagcgcgatt atgcgcacga acatcagagg gttggcttcc
     9061 ttgtaagcca tagtttgctt ttggataaaa tgccgaaaaa cggctacgca caccgtttgc
     9121 ggcgtcggta acacgagtaa agagaggaag tgagaaaaat acagagtgac gaagttgcta
     9181 ccggaggaga aatctccgca agtggtggag cgtagcttaa caagacattg tccagaacag
     9241 gacgttacca tccgcgatct ccatagtgac tgactatcac tgccgggaac ttccgctgct
     9301 acttaataat tacaacagat ctcgcattca ttgcaacaat atattcactt atatttaacc
     9361 ataaaacacc atttcagtga cattagtttc tactggaaag atgacagagt gatgacagat
     9421 atgaaaaaag ctgtgtgctt tcagcaggat tcgcatcagg catctgcgca cgaacgccgg
     9481 atgcggcgtg aacgccttat ccgcctaccg aacccgcacc gattgtaggc ataagaagac
     9541 gcgcaagcat cgcatcaggc atctgcgcaa gaacgcctta tccgtctata aacattaaac
     9601 ccgcaataac gcgcttccga gataatcgtt cgcgtccttc actcccggca gcgcaaaaaa
     9661 ataaccgccg ccgataggtt taacgtattc ctccagcgct tcgccattga gccttttttg
     9721 tacagtcagg aagccttttt ccagatcgtg ttggtaacag acaaacagta gccccatatc
     9781 cagttgcccg gagttggtga cgcccagtga ataactgtag ccacgacgca gcatcaggct
     9841 ggactcactc tccgccgtgc ggggattcgc cagccggata tggctgtcca gcgcaatcac
     9901 cttcccttcc ggatcgctgg cgtaatcggg aacatcatgc tcatgctgca ttcccagcgg
     9961 cgcaccggtt tgcttatcac gaccaaaaat cgtctgctgt tctttcagcg gagttctgtc
    10021 ccaaaattcc actcgaaact gaatcaagcg tactgcctga tagctgccac cgattgtcca
    10081 cgctggctcc tgctgatctg ccgttaccca caccactttt tgcatcaact tatcattctg
    10141 gctatcggga ttggcagtgc cgtctttgaa acccagcaaa ttaatcggcg tctctttgcc
    10201 tttactacgc gccgcgtgat cggaaataaa cccttcccgc ttccagcgca cgctgagcaa
    10261 atctggcgta tgtttgatga tatcgcgcag cgcatggatc accgtgtcct gggtgttggc
    10321 gcaaatttgt agcaacacat caccatgaca taacgccgca tccagcgagt cgttgggaaa
    10381 acgcgtcatc ttctgcaact ttttcggcat ctgtggcgca aggccaaagc gctcatcaaa
    10441 caatgagtga cccaccgata acgtgatggt gagattatcg ggcgcaatgt agccgccaag
    10501 aatgccggaa tcgagtggtg gcaggcgcgg atttggcgtt tctggtgccg ctccgccctg
    10561 agtcagaaaa gcaaaacgct gagtcaacaa gcgaaacaac cgttcaagat cgggtttatc
    10621 gctggcaagc acatcaaacg ccaccagcat cattgcggcc tgttgtggcg tcaggatccc
    10681 tgcctgatgc tcaccataaa acggctgttt ctcattgcgt gcatccggtg aaagcgtacc
    10741 cggcgcactt tgcgtttttt gtgcatgagc gaccggacaa cttcccgcca gcgccagcgc
    10801 accaatgcct ttcagtaaac gtcggcgtga cggttcattc acgccgtttt tatcttcata
    10861 ctgcataatg cttaatccaa tcccagcaca ccgcgaagtt gcgccagatc ttccgccagc
    10921 gcagtaatcg gtcctttcag tgcattccgg tcggcatcgg tcaatttgtc gtaggtttca
    10981 aaaccgtctt tagtacggta tttcgccaga atggtatcga cctttttaaa gttggcatcg
    11041 acttttgcca acagttccgg gttggctttt tgcagttgtg gacgcagcag atcgacaatt
    11101 ttctgcgagc cttcaacgtt agcctggaaa tcccacagat cggtgtggct gtagcgatct
    11161 tcttcaccgc tgattttgct ggctgccact tcctcaatca gtccggctgc accgccgacc
    11221 acttttgaag gtgggaaagc cagttcactg atgcgttttt gcaaatcgac cacatcggta
    11281 taaagctggt cagcgtactg atccatgcct ttggtggtgt tgtcgccaaa caatgctttt
    11341 tccagacggt ggaaaccggt gaatttcgga tcggcggctt tttgctcgta atcatcttca
    11401 cgggcgtcaa tgctgccatc cagatcggag aacagttcag caatcggttc gatgcgctca
    11461 tagtgctggc gcgtcggcgc atacagtgct ttcgcttttt cgatatcgcc tgctttaata
    11521 gcgtcagtaa aggctttcgt gtcggtcacc agctgcgtgg tttccgccat gacatacgct
    11581 ttatatgcag taattgcacc accaagactt aacagcgcat cactttgcgc cgcatccgcc
    11641 gttgcctcac ctttgacgat caacttccct ttcgggttag tcagcagacc gcaggtcata
    11701 tcgtattcgc caggctgtaa attcgccgtc attttctggc taaagccagg ggcgatattt
    11761 tcccgctctt ccaccaccat cacgcctttg aggatctccc actccagcgc cttctggctg
    11821 tggttctgaa taatgaactg tgttttcccg gcgttaaccg taatggtcat cggttcgcac
    11881 tgcttatcgg tcacggtcac cttgacctgc ggcacattag cggcgttagc cataaaagca
    11941 gaagagaaca gcgcagccac gctcaactgc aatgcgttac ggcggaagtt aatggtcatg
    12001 acgagactat ccctttaaag tatgttgtaa ctaagcaaga gtttgcgtcg tatttgctac
    12061 gcggagcgag acgctgtcgc ccctgcgcgt ggtggcaggg caaatgccac cagcgccggg
    12121 atgagataaa taaaccagac ggcgacttcg ctgacgctcg gtgcttcctg atagccaaaa
    12181 atcccttcca tcagcgtgcc aaacagcgag tgagttgaga ggaccgcgct catatcgaag
    12241 gcgatttcct gaaagtggtt ccacaatccg gcttcatgaa atgcgcgaat ggcaccagcc
    12301 gccagccctg cggcgacgaa gagaataaac aggctggtcc atttaaaaaa tgcaccaaga
    12361 ttgaggcgaa taccgcccca gtagagcagg aagccgagca ccacggcagt agcaagaccg
    12421 agcattgcac ccagcggcgg ccagatcccg acatcttgtt gaaatgccgc cagcaggaaa
    12481 aagaccgact ccagcccttc ccttgcaacg gcaaaaaaga ccatcatcac cagcgcccag
    12541 ccatgatgat ttccacgctg caatgcgcta tcgactgcct gttccagttg cactttgacg
    12601 ttgcgcgaca ctttgcgcat ccagaaaacc atccaggtaa ggatcaccac ggcgatcacc
    12661 gccacgatac cttcaaacag ttcctgttct ttttgcggaa attcgccggt ggtttcgtta
    12721 atgaagatac ccaggcccag gcacaacgca gcggcaagca acacgccaat ccacatcaca
    12781 ccaatccatc ggcctcgctg ggtacgctta aggtagctgg caatcaaact gacaatcagc
    12841 gcggcttcaa gtccttcgcg caacataatg agaaacggaa caaacatgcc acccaccctt
    12901 aaacgttttt ctgagtcaat ctatgcaaag aaaagtaaat cgcagtgata gcgattatca
    12961 ttacggtaaa gaaaaataca agcggaatgt ttataaaatg atgttggaat gtaaacaaag
    13021 agaggtaatg ccaagggata taaacgatta ttccagggta gaaagatggg attgtttgca
    13081 aagaaccatg tgttcttgcc ggatgccgcg taaacgccgt atccagccga caaaactgtc
    13141 cagactcaat gcatcagagc ttccatgtaa aactgataag cgggtgtatc aagcaatttc
    13201 gtccatccgc gattatcaaa tctaactttt tgcccggaac ataataacag ctcgggtgtt
    13261 ggtggcgtca aaatcgctga agcgttcccc gaaggccggg acagcagggg gcggcggcga
    13321 ttggccgccc cctgcgcgct ccctgcacca ttcaatttat atggcgaggc acattaaggg
    13381 agcgcaaccc gctgctgaag ccaaacaaaa ccgccgcagg ctaagtccct tagctttcct
    13441 gcaaccgtga cggcggagcc gaatgatagt gcgcatcggc ctcggcaaag cgtttttgca
    13501 tcgccgctga cggcgcttta cccagcaaac taaacactac aatcccaata ctgccgaaga
    13561 taaagcccgg aataatttcg tagagtccca gccagccgaa ctgcttccag acgataaccg
    13621 tcagcgcacc gatgatcatc cccgccagcg caccgttgcg cgtcatgcgt gaccacatca
    13681 ccgagaacag caccaccgga ccaaacgccg cgccaaagcc tgcccacgcg tagctcacta
    13741 agcccagcac gcggttttcc gggtttgccg ccagcgcaat cgccaccagc gccaccacca
    13801 gcaccatcac acgccctacc cacaccagct ctttctggct ggcatgttta cgcagaaacg
    13861 ctttgtataa atcttcggta atcgcactgg agcacaccag cagctggcag cttaacgttg
    13921 acattaccgc cgccagaatt gccgacagca gaatcccggc aatccacggg ttaaacagaa
    13981 tttgcgccag ttcgataaac acacgttcag cgttctggtt taccgcacct gctaccgccg
    14041 ggtgctcatt aaagtaagca atcccaaaga agccgacagc caccgcccct gccaggcaga
    14101 ggatcatcca ggtcatactg atacgacgcg catggacaat gctgtggtga gaatccgccg
    14161 ccataaaacg cgccagaata tgaggctgac cgaagtaacc cagcccccaa cccatcaatg
    14221 agataatggc aacaaagttc agccctttga gcatatccac gttttcgatg ctcttttgtt
    14281 tgatcacttc cagcgagtca ccaaagccac cgacactgat aatgacgata accggtgtca
    14341 ggatcagggc aaaaatcatc aggctggcct gtacagtatc agtccagctc accgcgagga
    14401 aaccgccaat aaaggtgtaa aggatcgtcg ccgcagctcc cgcccacaga gccgtttcgt
    14461 agctcatgcc aaaggtactt tcaaacagac gcgcgcctgc cacaatgccc gaagcgcaat
    14521 aaatggtgaa gaacagcaaa ataaccagcg cggagataat gcgcaaaatg cggcttttat
    14581 cttcaaagcg cccggtgaaa taatccggca gggttaaggc gttattgttg tattcggtat
    14641 gcacacgcaa ccgcccggcc accagcttcc agttgatcca cgcgcctaat gtcaggccaa
    14701 tggcgatcca gctttcggaa atcccggaaa gaaaaaccgc gcccggcaac cccattaaca
    14761 gccagccgct catatccgac gcacccgccg ataatgccgt cacgaatggc ccaagactac
    14821 gaccgcccag aatatagtcg tcaaagtttt tcgttgatcg ccaggcgata aacccaatca
    14881 atatcatgcc aaagatatag acacaaaatg tcaccaacat cggtgtgcta atagccatct
    14941 aaagtctcca aaaaattatt atcggcaatg tcgaaacttg ccgttatatc tgccaccgga
    15001 acggggtaac agagtttatg ttttaccagg gcgaccgtat cctgccggaa gcgctggtta
    15061 ttcacaatcg atttaacaca ccatttacat taaattttag tgctcagcga cactattttt
    15121 catcaggttg cactctctca cattttttgc ggttgcacct ttcaaaaatg ttaactgccg
    15181 cagagaaaaa gtctgattta tttttttaat ccctgtcata tcgatttctt ttattaacat
    15241 ttcattcatt tttaagcttg ctacgcaggt cacatttaac atggttgcac aaagttgcaa
    15301 catcatggat atttcacgat aacgttaagt tgcacctttc agaacaacag gagtaatggc
    15361 atgggaacca ccaccatggg ggttaagctg gacgacgcga cgcgtgagcg tattaagtct
    15421 gccgcgacac gtatcgatcg cacaccacac tggttaatta agcaggcgat tttttcttat
    15481 ctcgaacaac tggaaaacag cgatactctg ccagagctac ctgcgctgct ttctggcgct
    15541 gccaatgaga gcgatgaagc accgactccg gcagaggaac cacaccagcc attcctcgac
    15601 tttgccgagc aaattttgcc ccagtcggtt tcccgcgccg cgatcaccgc ggcctatcgt
    15661 cgcccggaaa ccgaagcggt ttctatgctg ctggaacaag cccgcctgcc gcagccagtt
    15721 gctgcacagg cgcacaaact ggcgtatcaa ctggccgata aactgcgtaa tcaaaaaaat
    15781 gccagtggtc gcgcaggtat ggtccagggg ttattgcagg agttttcgct gtcatcgcag
    15841 gaaggcgtgg cgctgatgtg tctggcagaa gcgttgttgc gtattcccga caaagccacc
    15901 cgcgacgcgt taattcgcga caaaatcagc aacggtaact ggcagtcaca cattggtcgt
    15961 agcccgtcac tgtttgttaa tgccgccacc tgggggctgc tgtttactgg caaactggtt
    16021 tccacccata acgaagccat cctctcccgc tcgctgaacc gcattatcgg taaaagcggt
    16081 gaaccgctga tccgcaaagg tgtggatatg gcgatgcgcc tgatgggcga gcagttcgtc
    16141 acgggtgaaa ccatcgcgga agcgttagcc aatgcccgca agctggaaga gaaaggtttc
    16201 cgttactctt acgatatgct gggcgaagct gcactgactg ccgcagacgc acaggcgtat
    16261 atggtttcct atcagcaggc gattcacgcc atcggtaaag cgtctaacgg tcgtggcatc
    16321 tatgaagggc cgggcatttc aatcaaactg tcggcgctgc atccgcgtta tagccgcgcc
    16381 cagtatgacc gggtaatgga agaactttac ccgcgtctga aatcactcac cctgctggcg
    16441 cgtcagtatg atattggtat taacatcgat gccgaagagg ccgatcgtct ggagatctcc
    16501 ctcgatctgc tggaaaaact ctgtttcgag ccggaactgg caggctggaa cggcatcggt
    16561 tttgttattc aggcttatca aaaacgctgc ccgttggtga ttgattacct gattgatctc
    16621 gccacccgta gccgtcgccg tctgatgatt cgtctggtga aaggcgcgta ctgggatagt
    16681 gaaattaagc gtgcgcagat ggacggcctt gaaggttatc cggtttatac ccgcaaggtg
    16741 tataccgacg tttcttatct cgcctgtgcg aaaaaactgc tggcggtgcc gaatctaatc
    16801 tacccgcagt tcgcgacgca caacgcccat acgctggcag cgatttatca actggcaggt
    16861 cagaactact atccgggtca gtacgagttc cagtgcctgc atggtatggg cgagccactg
    16921 tacgagcagg tcaccgggaa agttgccgac ggtaaactta accgaccgtg tcgtatttat
    16981 gccccggttg gcacacatga aacgctgctg gcgtatctgg cgcgtcgcct gctggaaaac
    17041 ggtgctaaca cctcgtttgt taaccgtatt gccgacacct ctttgccact ggatgaactg
    17101 gtcgccgatc cggtcactgc tgtagaaaaa ctggcgcaac aggaagggca aactggatta
    17161 ccgcatccga aaattcccct gccgcgcgat ctttacggtc acgggcgcga caactcggca
    17221 gggctggatc tcgctaacga acaccggctg gcctcgctct cttctgccct gctcaatagt
    17281 gcactgcaaa aatggcaggc cttgccaatg ctggaacaac cggtagcggc aggtgagatg
    17341 tcgcccgtta ttaaccctgc ggaaccgaaa gatattgtgg gctttgtgcg tgaagccacg
    17401 ccgcgtgagg tagaacaggc gctggaaagt gcggttaata acgcgccaat ctggtttgcc
    17461 actcctccgg ttgaacgcgc ggcgattttg catcgcgctg ccgtgctaat ggaaagccag
    17521 atgcagcaac tgattggtat tctggtgcgt gaagccggaa aaaccttcag taacgccatt
    17581 gccgaagtgc gcgaagcggt cgattttctc cactactatg ccggacaggt gcgggatgat
    17641 ttcgctaacg aaacccaccg tccattaggg cctgtggtgt gtatcagtcc gtggaacttc
    17701 ccgctggcta ttttcaccgg gcagattgct gccgcactgg cggcaggtaa cagcgtgctg
    17761 gcaaaaccgg cagaacaaac gccgctgatt gccgcgcaag ggatcgccat tttgctggaa
    17821 gcgggtgtac cgccaggcgt ggtgcagttg ctgccaggtc agggggaaac cgtgggcgcg
    17881 caactgacgg gtgatgatcg cgtacgcggg gtgatgttta ccggttcaac cgaagtcgct
    17941 acgttactgc agcgcaatat cgccagccgc ctggacgctc agggtcgccc tattccgctc
    18001 atcgctgaaa ccggcggcat gaacgcgatg attgtcgatt cttcagcact gaccgaacag
    18061 gtcgtcgtgg atgtactggc ctcggcgttc gacagtgcgg gtcagcgttg ttcggcgctg
    18121 cgcgtgctgt gcctgcaaga tgagattgcc gaccacacgt tgaaaatgct gcgcggcgca
    18181 atggccgaat gccggatggg taatccgggt cgcctgacca ccgatatcgg tccggtgatt
    18241 gatagcgaag cgaaagccaa tattgagcgc catattcaga ccatgcgtag caaaggccgt
    18301 ccggtgttcc aggcggtgcg ggaaaacagc gaagatgccc gtgaatggca aagcggcacc
    18361 tttgtcgccc cgacgctgat cgaactggat gactttgccg aattgcaaaa agaggtcttt
    18421 ggtccggtgc tgcatgtggt gcgttacaac cgtaaccagc taccagagct gatcgagcag
    18481 attaacgctt ccggctatgg tctgacgctt ggtgtccata cgcgtattga tgaaaccatc
    18541 gcccaggtca ctggctcggc ccatgttggt aacctgtatg ttaaccgtaa tatggtgggc
    18601 gcagtggtgg gtgtgcagcc attcggcggc gaagggttgt ccggtaccgg gccgaaagca
    18661 ggcggtccgc tctatctcta ccgtctgctg gcgaatcgcc cggaaagtgc gctggcagtg
    18721 acgctcgcgc gtcaggatgc agagtatccg gtcgatgcac agttgaaagc cgcattgact
    18781 cagccgctaa atgcactgcg ggaatgggca gcaaatcgtc cagaattgca ggcgttatgt
    18841 acgcaatatg gcgagctggc gcaggcagga acacaacgat tgctgccggg gccgacgggt
    18901 gaacgcaaca cctggacgct gctgccgcgt gagcgcgtgt tgtgtattgc cgatgatgag
    18961 caggatgcgc tgactcagct cgccgccgtg ctggcggtgg gcagccaggt actgtggccg
    19021 gatgacgcgc tgcatcgtca gctagtaaag gcattgccat cggcagtcag cgaacgtatt
    19081 caactggcga aagcggaaaa tataaccgct caaccctttg atgcggtgat cttccacggt
    19141 gattcggatc agcttcgcgc attgtgtgaa gccgttgctg cgcgggatgg cgcaattgtt
    19201 tcggtgcagg gttttgcccg tggcgaaagc aatatccttc tggaacggct gtatatcgaa
    19261 cgttcgctga gtgtgaatac cgctgccgct ggcggtaacg ccagtttaat gactataggt
    19321 taaacaggta gccggaggat gttacaacct cctccggcat ctttaacgtg gtcgaatccc
    19381 ctcaataata atccgctgca cgttttcaac cgtttgattg aaaaatatct catcgcgcaa
    19441 cgtcgcgcct gtcaccgcct ccacctgagg ggcgaaatcg gcgtaatgtt gagtggaagc
    19501 ccaaatcatg aaaatcaaat gctgcggatc aatcggcgcg agtttgccgc ttttgaccca
    19561 accggcaatc agcgccgatt tctcatcaat taatgccttc aaatcgcccg tcagttcatc
    19621 cattaacagc ggcgcgcctg ccagcatctc catacagaac aggcgcgaag cctgcggata
    19681 atcgcgggag acttccagct tcagacggat gtactctttt atcgccgcca gcggagcgaa
    19741 atcttcacga aacgctttta acggtgccag ccagatatcg agaatctgcc gcagcacggc
    19801 aatatacagc gcctcttttg acggaaagta atacagcaga ttggtttttg aaacacccgc
    19861 caactctgcg atctgctcca gccttgtgcc gtgaaaaccg aattgtgaaa aagtgtccag
    19921 tgctgcgcta agaatcgctt ttttcttcgc gcttactgcg cgcgaacgtt tacccgttgt
    19981 tttcactgcg ccttgcgtca tgcgctctcc cctcttgtag attggcaaca ggatagcaaa
    20041 acccccgccc ggcctcgacc ttctgcactc tcatcgcgca cagatgcatg ttttatgtgc
    20101 aactgttttg accgtttagt ccacttttta ccagatattt tagataacgc attgttaaca
    20161 tattaacaac attaactttt taaaaactgg catccgcttt gcaaacaagc cattacgcgg
    20221 ctgaaaagga tatgcaggat gcagcgcccc gtctgacttt cactttacga gacgaagaga
    20281 ggttgatgat gaaaattggc gtattcgtac ctattggcaa caacggctgg ctcatttcga
    20341 cccacgcgcc gcagtacatg ccgacctttg aactgaataa agccattgtg caaaaagcgg
    20401 agcactacca tttcgatttc gccctgtcga tgatcaaact gcgtggcttt ggcggcaaaa
    20461 ctgagttctg ggatcacaac cttgagtcgt tcaccttgat ggcggggctg gcggccgtca
    20521 cctcgcgcat tcagatttac gccactgctg ccaccttaac gttacctccg gcaatcgtcg
    20581 cccgtatggc cgcaaccatc gactccatct ctggcgggcg ttttggcgtc aacctcgtga
    20641 ctggctggca aaagcccgag tatgagcaga tgggcatctg gcctggcgat gactatttct
    20701 cccgtcgtta cgactatctc accgaatatg ttcaggtgct gcgcgacctg tggggcacgg
    20761 ggaaaagcga ttttaaaggc gattttttca ccatgaatga ttgtcgcgtc agtccgcaac
    20821 cgagtgtccc catgaaagtg atctgcgccg ggcaaagcga cgctggcatg gcgttctccg
    20881 cccagtatgc cgatttcaac ttctgtttcg gcaaaggcgt aaatacgccc acggctttcg
    20941 ccccgaccgc tgcgcggatg aaacaggccg cagagcaaac cgggcgcgac gttggttctt
    21001 atgtgttgtt tatggtgatt gccgatgaaa ccgacgatgc cgctcgcgcc aaatgggaac
    21061 actacaaagc gggcgcggat gaagaggcgt taagctggct aaccgaacaa agtcagaaag
    21121 atacccgctc cggtactgat accaacgtcc gtcagatggc cgatcccact tcggcggtaa
    21181 acatcaatat ggggacgtta gtcggttctt acgccagtgt cgcgcgcatg ttagatgaag
    21241 tcgcaagcgt gcctggtgcc gaaggcgtgc tgttgacctt cgatgatttt ctgtcgggaa
    21301 tcgaaacctt cggcgagcgc attcaaccac tgatgcagtg ccgcgcccat ctacctgcgc
    21361 tgactcagga ggtggcatga tgacaacctt aaccgctcga ccggaagcca ttaccttcga
    21421 tccgcagcaa agtgcgctga tcgtggtgga tatgcaaaac gcctatgcca cgccaggcgg
    21481 ctacttagat ctcgccgggt ttgatgtctc aaccactcgc ccggtcattg ccaacattca
    21541 aaccgctgtg accgcagcgc gagcggcagg gatgttgatc atctggtttc aaaatggctg
    21601 ggatgaacag tatgtcgagg ctggcggccc cggctcaccg aattttcata aatcgaacgc
    21661 cctgaaaacc atgcgtaatc agccgcagct gcaggggaaa ttgctggcga aaggctcctg
    21721 ggattatcaa ctggtggatg aactggtgcc gcagcctggc gatattgtgc tgccgaagcc
    21781 gcgctacagc ggtttcttca atacaccgct ggacagcatt ttgcgcagcc gtggaatacg
    21841 ccatctggtt ttcaccggta tcgctaccaa cgtctgcgtc gaatcgacgc tacgcgatgg
    21901 cttttttctg gagtatttcg gcgtggtgct ggaagacgca acacaccagg cggggccgga
    21961 atttgcacag aaagccgcgt tgttcaatat cgaaaccttt tttggctggg tcagcgacgt
    22021 cgaaacgttc tgcgacgcgc tttctcccac atcctttgct cgtatcgctt aaggagttta
    22081 acgatgccaa aatccgtaat tattcccgct ggcagcagcg caccgctggc ccccttcgtt
    22141 cccggcacgc tggctgatgg cgtggtgtat gtctccggta cgctggcttt tgatcaacat
    22201 aataacgtgc tgtttgccga tgacccaaag gcgcaaaccc gccacgttct ggaaactatc
    22261 cgcaaggtga tcgagacggc gggtggcacg atggcggatg tgaccttcaa cagcatcttt
    22321 attaccgact ggaaaaatta cgccgcgatt aacgaaatct acgccgagtt ttttccgggt
    22381 gataaaccgg cgcgattctg cattcagtgc ggactggtaa aacctgacgc gctggtggaa
    22441 atcgccacaa ttgcgcatat cgccaagtga ggccgcgatg aaactttcac tctcacctcc
    22501 cccttatgct gatgcgcccg tagtggtgtt gatttcgggt cttggcggta gcggcagtta
    22561 ctggttacag caactggcgg tgctggagca ggagtatcag gtagtctgtt acgaccagcg
    22621 cggcaccggc aataatcccg acacactggc agaagattac agtatcgccc agatggcagc
    22681 ggaactgcat caggcgctgg tagccgcagg gattgagcat tacgcggtgg tcggccatgc
    22741 gctcggtgcg ctggtgggaa tgcagctggc gctggattat cccgcgtcgg taactgtgct
    22801 gatcagcgtt aacggctggc tacgaataaa cgcccatacg cgccgctgtt ttcaggttcg
    22861 cgaacgatta ctgtatagcg gcggcgcgca ggcatgggtg gaagcgcagc cgttgttcct
    22921 ctatcccgcc gactggatgg cggcccgcgc acctcgcctt gaggcagaag acgcgctggc
    22981 actggcgcat tttcagggca aaaataattt actgcgtcga cttaacgccc tcaaacgcgc
    23041 tgactttagt caccatgcgg atcgcatccg ctgcccggtg caaatcatct gcgccagtga
    23101 tgatctgctg gtgccaacag catgttccag tgaacttcat gccgccctgc ccgatagcca
    23161 gaaaatggtg atgccctatg gcggacacgc ctgcaacgtg accgatcccg aaacgtttaa
    23221 tgctctgtta ctcaacgggc ttgccagcct gttacatcac cgtgaagccg ccctgtaagg
    23281 aattgctatg aacgaagccg ttagcccagg tgcgcttagc accctgttca ccgatgcccg
    23341 cactcacaac ggctggcggg agacacccgt cagcgatgag acgttacggg agctttatgc
    23401 cctgatgaaa tgggggccga catcagctaa ctgttctccg gcacggatcg tgtttatccg
    23461 cactgcagaa ggaaaagaac gtctgcgccc ggcgctttcc agcggcaatc tacaaaaaac
    23521 cctgaccgcg cccgtcaccg ctatcgtcgc ctgggacagt gaattttatg aacggttacc
    23581 actactgttt ccccacagtg atgcccgcag ttggtttacc tccagcccac aacttgccga
    23641 agaaacagcg tttcgcaaca gttccatgca ggcggcctat ctgatcgtcg cttgccgtgc
    23701 gctgggactg gataccggcc cgatgtcggg ttttgaccgt caacacgttg acgacgcctt
    23761 ttttgcgggc agcacgctga agagcaatct gctgattaat atcggctatg gcgatagcag
    23821 caaacttttt gcgcgcctgc cacgtctgtc ctttgaagaa gcctgcgggc tgttgtaagg
    23881 agcaaactat gaacatagtt gatcaacaaa cctttcgcga tgcgatgtcc tgtatgggcg
    23941 cggcggtcaa tatcatcacc acggacggtc cagccgggcg cgccgggttc accgccagcg
    24001 ccgtctgcag cgtgaccgat acgccgccca cattactggt gtgcctgaat cgtggggcgt
    24061 ccgtctggcc ggtattcaat gaaaatcgaa cgctgtgtgt aaatacactt agcgccgggc
    24121 aggagccgct ttccaacctt tttggcggca aaacgcccat ggaacaccgc tttgccgccg
    24181 cccgctggca gacgggtgtg accggatgcc cgcaactgga agaggccctg gtttcgtttg
    24241 actgccgtat cagccaggtg gtgagcgtcg gcacccacga cattctgttt tgcgccatcg
    24301 aagcgattca tcgtcacgcc acaccctacg ggctggtgtg gttcgatcgc agttatcacg
    24361 cgctgatgcg ccctgcttgt taacctcctt aaggagacag ctgatggcaa tgttcggttt
    24421 tcctcactgg cagttaaaat cgacctctac agagagcggc gtggtcgcgc cggatgaacg
    24481 gttgccgttt gctcagacgg cagtaatggg cgttcaacac gcggtggcga tgtttggcgc
    24541 gacggtgtta atgccgattc tgatggggct ggatcccaat ctttccattt taatgtcggg
    24601 gatcggcacg ttactgtttt tctttattac cggcgggcgc gtccccagtt atctcggctc
    24661 cagcgcggct tttgtcggcg tggtgatcgc cgcgacgggc tttaacggtc agggcatgaa
    24721 cccgaatatc agcatcgcgc tgggcgggat tatcgcctgt gggctggttt ataccgtcat
    24781 tggcctggtg gtgatgaaaa tcggtacacg ctggattgaa cggctaatgc cgccggtggt
    24841 gacgggtgcg gtggtgatgg cgattggcct gaacttagcg cctatcgcag tgaaaagtgt
    24901 atcggcttcg gcctttgata gctggatggc ggtaatgacg gtgctgtgta ttgggctggt
    24961 ggcggtgttt acccgaggca tgatccagcg gttattgatt ctcgtaggat taattgtcgc
    25021 ctgtctgctg tatggcgtga tgaccaacgt tttagggctg ggaaaagccg tcgattttac
    25081 tctcgtcagc catgctgcct ggttcggttt gccacatttt tccactcctg cttttaatgg
    25141 tcaggcaatg atgctgattg cgcccgtggc ggtgattctg gtggcggaaa acttaggtca
    25201 tctcaaggcg gtcgccggga tgaccggacg caatatggac ccgtatatgg ggcgagcatt
    25261 cgtcggtgat ggtctggcaa cgatgctttc cggctctgtc ggcggtagcg gcgtcaccac
    25321 ctatgctgaa aatatcggtg tgatggccgt gacaaaagtc tactcgacgc tggtgtttgt
    25381 tgctgctgcc gtcatcgcca tgctgttggg cttttcgccg aaatttggcg cgctgatcca
    25441 taccattccg gccgcggtga ttggtggtgc atcaattgtt gtgttcgggc tgattgccgt
    25501 cgcaggcgca aggatatggg tacaaaaccg tgtcgattta agccagaacg gtaatttgat
    25561 tatggtcgca gtaaccttag tgctgggcgc gggtgatttt gctctcacgc tgggcggttt
    25621 tacgttggga gggattggta cagcaacctt tggcgcgatt ttactcaatg cgttgttaag
    25681 cagaaagttg gttgacgttc caccgccaga agttgttcat caggagccat aaacagaaaa
    25741 ccgccgggat taccggcggt gatgactttt tgacgagcct aagaaaaaaa tgcattcgtc
    25801 attgattagc ccggctagtt gtcgcttttg ccgtgactgc tcttgccacc ttttttacct
    25861 gcttcagatg cgcgctgcgg gtcattcttg aaattacccc cgctgtgctg tccacctttt
    25921 ttacctgctt ctgatgctct ttcgcggtct tctgcaaaat tgccggaacc gcctcgatgg
    25981 tttgccatta ctgacctccg tctgggtata gacatcatat tgcatagaat taacgcggcg
    26041 tatggcggct gccatatttt cgctacgtgg gactaagctt agtgaactga cgcgggcaga
    26101 cccgcgtttg gtaatatcct gcaacagctt cttagcgaga atagatatca tctcaaataa
    26161 ttatccataa gccgctctta tgattaaaaa aacgcgatga gataaaaatg tgtcattttg
    26221 cgacaaaatt acgtgcttgt gaaagttgtt ataaatcaaa taagtggttg tgaaatttgc
    26281 actctgaaaa ggacgtctta tctttaaata agtggtagcg aatcgctacg gaatagagat
    26341 aacacgagga gtggttagaa atggctaaag ttctggtgct ttattattcc atgtacggac
    26401 atattgaaac gatggcacgc gcagtcgctg agggtgcaag caaagtcgat ggcgcagaag
    26461 ttgtcgttaa gcgtgtaccg gaaaccatgc cgccgcaatt atttgaaaaa gcaggcggta
    26521 aaacgcaaac tgcaccggtt gcaaccccgc aagaactggc cgattacgac gccattattt
    26581 ttggtacacc tacccgcttt ggcaacatgt ccggtcaaat gcgtaccttc ctcgaccaga
    26641 cgggcggcct gtgggcttcc ggcgcactat acggaaaact ggcgagcgtc tttagttcca
    26701 ccggtactgg cggcggtcag gaacaaacta ttacttcaac ctggacgacc cttgcgcatc
    26761 acggcatggt aattgtcccc attggctacg cagcgcagga attatttgac gtttcacagg
    26821 ttcgcggcgg tacgccgtac ggcgcaacca ccatcgcagg cggtgacggc tcacgccagc
    26881 caagccagga agaactgtct attgctcgtt atcaagggga atatgtcgca ggtctggcag
    26941 ttaaacttaa cggctaatct tcaacaggag gatacgcatg ccaactcaag aagcgaaagc
    27001 tcatcacgtc ggtgaatggg catctctgcg caatacgtcg ccggaaatag ccgaggccat
    27061 tttcgaagtc gccgggtacg acgaaaaaat ggcggaaaag atttgggaag aaggtagcga
    27121 tgaagtgtta gtcaaagcct ttgctaagac cgataaagat tcgctttttt ggggcgaaca
    27181 gaccatcgaa cgtaaaaacg tttaaccagc gactcccccg cttctcgcgg gggagttttc
    27241 tgttatttca ccgcttcatt caacacgcta tcaaatttat ccatcgggca gaaaccgttg
    27301 gcatctatcg ggcaaccgct taattccagc gtcacacgct gagcaggtgc ctgcagggtt
    27361 aacgcatcgg cattacgtaa ctgttccgca ctctgataca catattcaat tttcatcaaa
    27421 tcgcgattgg ctttgctgtc atgccaacgc tggaaaacga ttttgccgcc aatcggcgtg
    27481 cgttcgttct ggtcatgcaa ctgatacggt ttgaaatcca gcgccgttaa cagagaggca
    27541 atgttggagt cgtgcccaac caacactgta attttcggtg cgctggtgcg atcggtgacc
    27601 agagctttgt cgatataact gaccagcggt ttcgcaacat tgcgcgccac ttccggtgag
    27661 gtaaacaggc tgtcctggta gccgttttta agcttcgaca acaccttcca ctgctggtca
    27721 gatttgattt ctccccaggc cacctgatcc atcggaaaac cttcgtaata ttgcaaagta
    27781 aacgcatcta ccagcgagtt gccgactttc agcggcccgg aaacacctgg ttcttgttga
    27841 tacttggcgc taaaggtatt tttgccatcc accagcgaac actgttgttt ctctttacag
    27901 gcaggggaat ctttatagtt aacgattttt tccagtagct ggtagctgtc ggtaagctgg
    27961 agtttgctga gctctttctc cattgccgcc accgcctgtt cactgaatgc ggcggaatca
    28021 tcggtgatca ccgggttaaa ggttgggtcc atagtgccca ttttttcctg gtgatgcaca
    28081 ggaatatcac accccgggaa tgcgccggta ataaagaact gtgcggtcgc aacggtacgt
    28141 tgcagactat tggcataggc ataaacggtg tacggcggcg ggcattcccc cgatttcacc
    28201 atcccctgct ctgccagcca ttcacgcatg taatggccca tatacacttc gagcacgcca
    28261 cctttggtgg tgagttgccc accggggacg tcccattctg gccatttatt cggcgtcgac
    28321 tgctccagca cactgccatt gttcgccagc ggcgcacgta agttatggcg gctcatcatg
    28381 agcacttgct gtagctgata gccttccggt acggtttgtg cctgagcgtt tgaagcgagt
    28441 aaaactatcc ctgccacagc tgcggcgatt agcgttttgt tcattcctgg cacctctttt
    28501 gttatcaatc actaaagagt gtgacagaaa tatgactttt ttccgggaac aggttcgcaa
    28561 aatggcttgt tgaacgcctg tttttctata tacatcttca aaaacaggca aggtttgacg
    28621 caaactatgc ctgattagcc cctgcctcgc gtacgccgct gataattgca cctgtggcta
    28681 aacagaatat ctgcggcgtt accaatacag agacaatatt taccaataaa aaagtgtgag
    28741 actaataaca atggttttta gcatatgcct ttgccattaa attgcataac gatttaaata
    28801 gtcgagttgc gcattcattt ccttattttt taacttgtaa gcctgagcaa aaagttcagg
    28861 agggaggtaa acatcataat gattgccagt gtttattaaa taaccatact caagatcttc
    28921 atctgttgaa aaggattcat tccctaagga gattgatgcc acattactat taacaataaa
    28981 taatgagcaa atgctatctg aaagagcagt gaggaaattt ttcacctcat taatcctctt
    29041 ctctgggtcg gtgtctaaaa caaggcgtgc cttgttatca ttaaatataa actcgggtaa
    29101 atgcagtatg cattttttgt cattcaagca actatcaata aattattttt taaaaaacag
    29161 aaagttccat gacataagac taccctcccc ctgaattttg ttgtcagatt gtagatcaac
    29221 gccaaataac gtctttacat cttccctgag attatagaat gccgtatcaa caagagcctc
    29281 gatcgtttgt ttatcaacaa ttttaataaa ctcttcgtat acttgctttt gcgtcttatg
    29341 gctgcccagc gcccatgaat actcatgttc ttttaaaacc agtatggccc ttaacagaca
    29401 atagccatcg ccatctactg gagcgtattt taatccataa gttttattaa tttcactctg
    29461 aataaaagat ataccagaca aatcaatacc agaatctaaa tcagatattc ccggcgtatt
    29521 tatctgttct ggctggatac tcatattttc atcatctaaa caatactcag aaaaaacatc
    29581 atcacacgca gtaatgtttt caatatattc cataaagcca taccaataat aacctttaaa
    29641 atctgtgata gactctgaac ctctgcccgg caaggacact ctaacaatat caacattttg
    29701 aacatattgt atagtatatg taatacctcc tgaaacccct gaataaattt gtgtatcatt
    29761 agtacgcaat gttctcataa ataatgatag atcattatca ttctgcattt cctcaaattc
    29821 tttttctagt gattcacatt ccagacatgg agtatcctct tcatttactt tacgtctgag
    29881 ttcattgtat aaccgcataa aacacaccag tgtgttttca aaaagcgtga ttgaatatgt
    29941 ttgatttttt tcgtactcat tttttatatc gttccaggcc tgtttcaaat aattatttgc
    30001 agtgcaacta attccatgta tattactacc catatatagc gtctatgaaa tttaataaat
    30061 aatgacgccc cagttaaact taaagtgcct ggttcaacta tcaaaaatcg ctcacccttt
    30121 ttcacctgtt taaaatatgt tcagtaaccc atcttgatgg cgacctcctc tccgcgatga
    30181 tttcaataac atattctgtg ttggcatatg aaattttgag gattacccta cacttatagg
    30241 agttacctta caggggttcc ttcaatttgt gttgatttac gcgagataac gctatggaat
    30301 taaaggatta ttacgccatc atgggcgtga aaccgacgga cgatctcaag acaatcaaga
    30361 ccgcctatcg tcgacttgcc cgcaaatacc atcctgatgt cagcaaagaa ccggatgccg
    30421 aagcccgctt caaagaggtc gctgaagcct gggaagtgtt aagtgatgaa caacgtcgcg
    30481 ctgagtatga tcagatgtgg caacatcgca acgatccgca atttaaccgt cagttccatc
    30541 atggcgacgg tcagagtttt aatgccgaag attttgacga tatcttctcg tcaattttcg
    30601 gtcagcatgc ccgccagagc cgtcaacgcc ccgccgcacg cggccacgat attgaaatcg
    30661 aagtggcggt attcctcgaa gaaacgctga ctgagcataa gcgtaccatc agctataacc
    30721 tgccggttta taacgccttt ggcatgatcg aacaggaaat cccgaaaacg ctgaatgtga
    30781 agatcccggc gggcgtcggc aatggtcaac gcatccgtct gaaaggccag gggacgccgg
    30841 gcgaaaacgg tggtccaaat ggcgatttgt ggctggtgat tcatattgcg ccacatccgc
    30901 tgttcgatat tgtcggccag gatctggaaa ttgtggtgcc ggttagcccg tgggaagcgg
    30961 cgctgggtgc taaagtcacc gttccaacac tgaaagaaag cattttgctg actatcccgc
    31021 caggcagtca ggccgggcaa cgattgcgcg ttaaaggcaa aggtctggtg agcaaaaaac
    31081 agaccggcga tctgtatgcg gtactgaaaa tcgtgatgcc gccgaaaccg gatgaaaaca
    31141 ctgccgcgct gtggcagcaa ctggcagacg cccagtcgtc ttttgatcca cgtaaagatt
    31201 gggggaaagc atgatggcta atgttacggt gacttttact attaccgaat tttgcctgca
    31261 taccggcatc tctgaagagg agttgaatga aattgtcggt ttgggggtgg ttgaaccgcg
    31321 tgagatccag gaaacaacct gggtatttga cgaccatgcc gccattgtgg tgcaacgcgc
    31381 ggtacgcctg cgtcatgaac tggctctgga ctggccgggg atcgcggtgg cgctgacgtt
    31441 aatggatgat attgcacacc tgaagcagga aaaccgcctg ctacgccagc ggctttcccg
    31501 gtttgtagct catccgtgat gtgtgtttgc cggatgtgat gacgcatccg gcaactgcgc
    31561 cataatgcct gatgcgacgc taaacgcgtc ttttcaggcg cataaacgac gttatctgtt
    31621 ttggtggtcg cactccacta acaccagcaa taactggctt agtgccgcgt aaaaaccaaa
    31681 gctgtcatac tgatggcaac gcgcagcaaa ctctggtaac cattgccaca gcgccgtcag
    31741 tgttttttgc cgcaaactgt cgattcttcg cgcaggaacg gtcccctctc ccagcgaaaa
    31801 atgcagatga ctcaacaact cgagatagat cgccagatgg tctgccggtt cgttgaaatt
    31861 gccgctggtt tccatccctg cctcaactaa caagcgttta atctcttgct cgtcctgttt
    31921 gtaggccgat gcatacggca gcgccgcttg tttgtcggtc atcagaaaca ggccgcaaaa
    31981 gtcagcggcc agttccagac gggcatcgtc acgtactgtc agcgtggcaa tacagttttc
    32041 cagctcattc accgccgcag ccagcggcgg ttcgcttttc agcaacgaaa accattcagc
    32101 catctgcgca ctggcgattt gcgtcagttg ttcatcgtcc agttcacggg agaacaactg
    32161 cgccagccag gcgtaaacac aggcaatctg ttgtgctgtc agcgtggtca tgatttcacc
    32221 tgcgacgcgg gaacatattc gcactgcgcc accatctcca cagggccgtt aaacgccgtc
    32281 acctgctcca ctgctccatt gtacttctca atttccacca gcgtagtgtg cgcactggtc
    32341 gcctgcgcca gctgcgaagt accgatgtcg atggtcagca cgttggggtt accgtatttg
    32401 cacagcgcac caggctcgcc gcctttatct ggatcgtacc atgccccttc gtgaattcgt
    32461 gccacgccgg gtgcatagcg gtcagaaact actgcccctg ccaacacctg accgcgagcg
    32521 ttaaagacgc gtaccacatc accgttacga ataccgcgcg cgctggcatc ctgcgggtta
    32581 atgaacactg gctctttacc cgctaccgta tattgctgac gcagagtttc cgactcacat
    32641 aactgcgagt gaagtcggaa atccggatgc acagattgca gatgcaacgg atacttctgc
    32701 gagccgggcc caccgtggga gcgttcgatt ttctcaaacc acatcggatg cccctgacaa
    32761 tcgtcgtagt tcatatcggc gatggttttc gagtagatct caatcaggcc actcggcgtg
    32821 cccagcggtt cgagatccgg atcttcgcgg aatgcctggt ggcgaacaaa catctgcgga
    32881 tggtcaaact cgacgtactc tttgttattc cagaagtcat caaacgctgg cagatgaacg
    32941 ccgcgtcctt tgccttgttg tacaccttcc tgccagatgc gtttcagcca gcccatttcg
    33001 tccagccctt cggtaaaggc ttcttcgcga ttaaagcgac ggcacagctc gcggaaaata
    33061 tcaaagtcgt tgcgcgcctc gaactgcggc ggcaccacct gtttcatggc gataacgcca
    33121 cggttggagt ggttgccgta ctggtcgaga tcgttacgct caaactgcgt ggtcgcaggc
    33181 agcacgatat cggcaaagcg gcaggttgag gtccactggt tatctatggc gataaccgtt
    33241 tccagcttgc gccagccttc aataatgcgg ttgatctgct gatggcgatg gaatgggtta
    33301 gttccggcaa aaatacacat tttcagcggc ggcagtttta ccgatttacc gttccagttg
    33361 atcactttcc ccggttcgag gatcgcatcg ataaaacggg caatcggaat ggtgctgctg
    33421 tagcctttgt aatcactgtt gtcgtgaaca ggcggaatcg acgtagagcc ggagaaacca
    33481 ctcagaataa cgcctttacg ccccggcgtg cctgcgccgt tatagtgcca gccaaaacca
    33541 aagccaccac ctggcaggcc aatttgcccc agcatcgccg ccagaaccac aatcatccac
    33601 gcccactgtt caccgtgctg catacgctgc acgcaccagc cagcaataat ttgcgttctg
    33661 ttcgccgcca tctgccgcgc cagcccacga atggtttcgg catcaatgcc ggtcagtttt
    33721 tcagcccatg cggcatcttt cggctgaccg tctttctcac ccagcaggta cggcaggaac
    33781 tgctcaaaac ccacacagta gttagcgagg aagtttttgt cgtacaggtt ttcactgtac
    33841 agcgtatacg ccagcgccag ttgcagcggc acatcagttt gcgggttaac cgcaatgtgc
    33901 ttcacatgct cgcgccccag atactcatgg gtggatgtga caaccggatc gatgctgatg
    33961 acctcaattt caccggcggc gactttcgct tttagctgcg cgtaatattc ataaacatcg
    34021 tgatccgggc accaccagtt cgcttgctgg tttttcagca aatcagagcc ccacagcaca
    34081 atggttttgc tgttctgcaa taccagcggc caggaggttt gctgttcata cacttccatt
    34141 gagccaacca cgcgcggcag gatcacctgc gcagcaccgg tagagtaatc tccgcccgta
    34201 ccaacgctat taccatgcaa ggcaatagct ttcgccagca tccccgaagc gttatggaac
    34261 atccccgtcg attgccaacc actggcggtc agcaaggcac tcggcccgtg agttttctgc
    34321 acgcgttcca gttcttcata gaacatgtcg agggcttcat cccagctcac gcgcacaaaa
    34381 cggttatcac cgcgctggga ggtatcgctg agatggcgct tacgcagcca gtccacgcgt
    34441 accatcggat aacgaatacg cgccgcgttg tgtacgtgat ccggcaatcc ggcaatcatt
    34501 ttcgacggat atttatccag ttcgaacggt tttgccgcca caaagcgacc atccttcacc
    34561 gtcgcgcgga tagcccccca gtgcgacccg gtaagaatgc cctctttcga gatgacagcg
    34621 tcagtcgccg cttgcgccgc agtcgcacgg cgcggcgtta acaatgacgg ccccagcatc
    34681 ccggcgacgg ttaagccgcc gagttgtgcc agaaaacgcc gacgtgatgc ctgaaagaga
    34741 tcgttattgt tcattatttt tcttccttct tatcgccgtg agccttacct gcggtgtcag
    34801 acgcattcat ttgcagatat ttcaacaagg tgcgttcttc acgtttatcg agactggtaa
    34861 agccaatcat gccgttgagc gtgccgatcc aaccgttagc gtcaaagtgg gcgatttccg
    34921 gtgcgccgtg gcactggtta caggtgccgt tgtacaacga atccgcataa gcccagatcg
    34981 gtttgatatc gttcaccatg tcgcctttct tcatccacgc agtggcctgc aacttgctcc
    35041 actcggtatt ggtgtcggca acggtggttt tctccagcgt ttttacctgc tgctgcacat
    35101 caccacgaat cgaggcaaca aagatgcgtt tacctgggaa ttgggtgagt acacgctgac
    35161 gtccggcgct ttccgtccag ccggtaattt caatttgcag ccagtcgccg tcacgtttaa
    35221 ggactttcac ttccgaagca ggcagcagag aaccagaggc ttctttatcg cctttcgccg
    35281 cataaattgg cttaatatca atagagtaca gcgtgtcacc actgtcatta gcactggcgc
    35341 gcagctcatc gaactgctta cggaagccgc tactcatatc cggtaactgg tgggcaatac
    35401 ctttatgaca gtcgatgcag gattgattat ctttcgctgc caccttcatc tgacgtgccg
    35461 cttcaggatg ctgcttcgca tgatccatcg catcgtagtt atggcaggag cggcaggttg
    35521 ccgagttgtt ttctttcatt cgcgcccatt cacgctcggc aagttccgcg cgtttggctt
    35581 cgaatttttc aggtgtatca atggagtgag caataaaggt ctggtagata tcattgctcg
    35641 cttccagttt gcgcttcacc atgcctggaa tatccggcgg gatatgacag tcatggcatt
    35701 cagctcgcac gccggaggcg ttctggaaat gcaccgactg tttatattct tcatacaccg
    35761 gttgcatact gtggcaactg acacaaaatt cggttgtgct ggtgactttg atcccaacgt
    35821 gtggcaatac aatcagcgca atgccaatca caatcccaat tgcgaccagc gccagtaccg
    35881 accaacgagc actgggtcgg cgtagcgcgt tccagagttt ccgcataata gcccctgtaa
    35941 aattatggtt tagtgaagcg atcttaatga gcaaatatga acagcggcac tggtcaggat
    36001 gaacggctta cggcagaata tgaacagata tgaacagaat gagtaaaacc ctctgatgcc
    36061 acatcacatt gttattgttg aagatgagcc ggttacccag gcgcgattac aatcttactt
    36121 cactcaggag gggtataccg tttccgttac agcgagcggt gccgggctgc gggaaattat
    36181 gcagaatcag ccggtagatt taattctgct ggatatcaac ttacccgatg aaaatggcct
    36241 gatgttaacc cgcgccctgc gagaacgctc aacggtgggg attattctgg ttaccggacg
    36301 cagcgatcgg attgaccgta ttgttgggct ggaaatgggc gcagacgatt acgtcaccaa
    36361 accgctggaa ctgcgcgaac tggtagtacg ggtgaaaaat ctgctctggc gaatcgacct
    36421 cgcgcgacaa gctcaaccgc acactcagga caactgctat cgctttgccg gttattgcct
    36481 gaatgtgtcg cgccatacgc tggagcggga tggcgagccg attaaactga cccgcgcaga
    36541 gtatgaaatg ttggtggcat ttgtgacgaa tccgggcgaa attctcagcc gtgaacgtct
    36601 gctacgtatg ctttctgcgc gtcgggtgga aaaccctgac ctgcgcaccg tcgatgtgtt
    36661 aattcgtcgt ttacgtcata aactcagcgc ggatttactg gtgacgcaac atggtgaagg
    36721 ttatttctta gccgctgatg tgtgctgata aaaatagacc ggacgaaatc cccctggtga
    36781 cagcgagcgg cgaatatgtt cacggtcggc atttttcggc gtcagaacta aaatcggtgg
    36841 gctgacatta tcagacaccg attgcccctg taattgcctg atggcctgct caaccgccag
    36901 ttccccctgc cagaccattt gatcgctggc agccataatc actcttcccc gcttcagccc
    36961 gcgatacacc tgatgtgaaa gataaaacga caccacggta agcggcgttt tcaggttacg
    37021 cccttcaccc attgccgcct ctgccgcaat ggccgttccg gcaacgacgt cgatttctgg
    37081 gtggcgttcc agcatctcct gcaacaggtt acgctggatt tcaatatcgt tatcaccaag
    37141 cgcaatatca acaatacgca ccgggcttcc ggcaatggct gcgcgaaaac cctcgaccat
    37201 ctctttactg cccccggcat tatcgggtcc gggcatcaac agcacgttca gtggtttacc
    37261 gtgcgcccat tgcaccaaat atcgcccagg ttgatagccc atctgaaacc agggtacacc
    37321 aacgcggctt ttcaccaggg gatcatcaag agcatttacc agttcgatca ccggcagatt
    37381 tgctacctgc ttttgcaggt cgggaaatga cgtagtgcta ctaccgagca aaatggcctc
    37441 tgcgccccac tgtttacact ggtcgatttg tgcttgctgg gtagccaact ggctgtagcc
    37501 gcctgcctcc agcactttta aatccacacc atagcggcga gctgcctcct gcataccata
    37561 gttcaacgat aaccagtatg aatctttcag gctgggataa agcgcgcaca gtttccatgc
    37621 gcgtttggct ttaagcggcg tagaggcttg caccgtgtaa tgctgcgcat catgccagcg
    37681 caacaggtta tcagccgaaa atgccgataa catgaaaagg gaaagaagta aaaatagcag
    37741 tacgcgcatg atagcctcat caataataag gctttatgct agatgcattc cgctttgcga
    37801 ctcaaccttt ttcacctaaa ggatgacaaa tacacacaaa tattttaaaa atcatattgt
    37861 tacatgaatt catgattaaa taacagactg caaaatacga taaaacacta catctagagt
    37921 cactattaat caatgagtta gatgtggtta gtgacctaca acagagcatt agcgcaaggt
    37981 gattttttgt cttcttgcgc taattttttg tcataaaaac atgtggcaga ctttgtatat
    38041 ctctgctttg ccacgccaca ccatcatgca ttatggctat gcctaaa
//
LOCUS       DAZUDJ010000047        37568 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.047, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000047 DAZUDJ010000000
VERSION     DAZUDJ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37568
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.047"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..247
                     /gene="yfdT"
                     /locus_tag="ACHY1N_003109"
     CDS             <1..247
                     /gene="yfdT"
                     /locus_tag="ACHY1N_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein YfdT"
                     /protein_id="HFS4045386.1"
                     /translation="EVRDDIERRAYEIALVSLEVEPDEREAYELFMEKRFGDLVDRRR
                     AKNGDNEYMAWDMTLGWIVWQQRAGIHFSTMSQQEVK"
     gene            163..342
                     /locus_tag="ACHY1N_003110"
                     /pseudo
     CDS             163..342
                     /locus_tag="ACHY1N_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518805.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            474..1637
                     /gene="intD"
                     /locus_tag="ACHY1N_003111"
     CDS             474..1637
                     /gene="intD"
                     /locus_tag="ACHY1N_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFS4045387.1"
                     /translation="MSLFRRNEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAE
                     LWRVEKLGDLPDVTFEEACLRWLEEKADKKSLDSDKSRIEFWLEHFEGIRLKDISEAK
                     IYSAVSRMHNRKTKEIWKQKVQAAIRKGKEPPVYEPKPVSTQTKAKHLAMIKAILRAA
                     ERDWKWLEKAPVIKIPAVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRKSN
                     IINLEWQQIDMQRRVAWVNPEESKSNRAIGVALNDTACKVLRDQIGKHHKWVFVHTKA
                     AKRADGTSTPAVRKMRIDSKTSWLSACRRAGIEDFRFHDLRHTWASWLIQSGVPLSVL
                     QEMGGWESIEMVRRYAHLAPNHLTEHARKIDDIFGDNVPNMSHCGIMEDIKKA"
     gene            complement(1653..1729)
                     /locus_tag="ACHY1N_003112"
     tRNA            complement(1653..1729)
                     /locus_tag="ACHY1N_003112"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1693..1695),aa:Arg,seq:tct)
     gene            1972..2604
                     /gene="fimZ"
                     /locus_tag="ACHY1N_003113"
     CDS             1972..2604
                     /gene="fimZ"
                     /locus_tag="ACHY1N_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis transcriptional regulator
                     FimZ"
                     /protein_id="HFS4045388.1"
                     /translation="MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDY
                     LRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANG
                     FVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
                     LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI"
     gene            complement(2607..3122)
                     /gene="sfmF"
                     /locus_tag="ACHY1N_003114"
     CDS             complement(2607..3122)
                     /gene="sfmF"
                     /locus_tag="ACHY1N_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria assembly protein"
                     /protein_id="HFS4045389.1"
                     /translation="MRRALFSCFCGLLWISSGWAADPLGTININLHGNVVDFSCTVNT
                     ADIDKTVDLGRWPTTQLLNAGDTTALVPFSLRLEGCPPGSVAILFTGTPASDTNLLAL
                     DDPAMAQTIAIELRNSDRSRLALGAASPTEEVDANGNVTLNFFANYRALASGVRPGVA
                     KADAIFMINYN"
     gene            complement(3133..4140)
                     /gene="fimH"
                     /locus_tag="ACHY1N_003115"
     CDS             complement(3133..4140)
                     /gene="fimH"
                     /locus_tag="ACHY1N_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria D-mannose specific adhesin FimH"
                     /protein_id="HFS4045390.1"
                     /translation="MKIICRLLLAMACLCLANISWATVCANSTGVAEDEHYDLSNIFN
                     STNNQPGQIVVLPEKSGWVGVSAICPPGTLVNYTYRSYVTNFIVQETIDNYKYMQLND
                     YLLGAMSLVDSVMDIQFPPQNYILMGTDPNVSQNLPFGVMDSRLIFRLKVIRPFINMV
                     EIPRQVMFTVYVTSTPYDPLVTPVYTISFGGRVEVPQNCELNAGQIVEFDFGDIGASL
                     FSAAGPGNRPAGVMPQTKSIAVKCTNVAAQAYLTMRLEASAVSGQAMVSDNQDLGFIV
                     ADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPTEGPFSALGYLRVDY
                     Q"
     gene            complement(4153..6761)
                     /gene="sfmD"
                     /locus_tag="ACHY1N_003116"
                     /pseudo
     CDS             complement(4153..6761)
                     /gene="sfmD"
                     /locus_tag="ACHY1N_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308621.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0015473 - fimbrial usher porin activity
                     [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
     gene            complement(6792..7484)
                     /gene="fimC"
                     /locus_tag="ACHY1N_003117"
     CDS             complement(6792..7484)
                     /gene="fimC"
                     /locus_tag="ACHY1N_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HFS4045391.1"
                     /translation="MMTKIKLLMLIIFYLIISASAHAAGGIALGATRIIYPADAKQTA
                     VWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAAD
                     RESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSR
                     SGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVSSQIPLPSGVQGKLKFQTVNDY
                     GSVTPVREVNLN"
     gene            complement(7704..8246)
                     /gene="fimA"
                     /locus_tag="ACHY1N_003118"
     CDS             complement(7704..8246)
                     /gene="fimA"
                     /locus_tag="ACHY1N_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308619.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HFS4045392.1"
                     /translation="MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVN
                     TDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAIND
                     NLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
                     GTSASAGQANADATFIMRYE"
     gene            8727..9593
                     /gene="folD"
                     /locus_tag="ACHY1N_003119"
     CDS             8727..9593
                     /gene="folD"
                     /locus_tag="ACHY1N_003119"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HFS4045393.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLP
                     AGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG
                     DWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTL
                     QACVEYHDPQDE"
     gene            9595..9807
                     /gene="ybcJ"
                     /locus_tag="ACHY1N_003120"
     CDS             9595..9807
                     /gene="ybcJ"
                     /locus_tag="ACHY1N_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HFS4045394.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGA
                     VETRKRCKIVAGQTVSFAGHSVQVVA"
     gene            9915..10436
                     /gene="ybcI"
                     /locus_tag="ACHY1N_003121"
     CDS             9915..10436
                     /gene="ybcI"
                     /locus_tag="ACHY1N_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFS4045395.1"
                     /translation="MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLS
                     FKFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSL
                     LDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLP
                     GMVLMGMLWWRRR"
     gene            complement(10472..11857)
                     /gene="cysS"
                     /locus_tag="ACHY1N_003122"
     CDS             complement(10472..11857)
                     /gene="cysS"
                     /locus_tag="ACHY1N_003122"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFS4045396.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDA
                     LNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDL
                     DQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAG
                     GEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLG
                     LLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLE
                     DGPQGTTWRRK"
     gene            12031..12525
                     /gene="ppiB"
                     /locus_tag="ACHY1N_003123"
     CDS             12031..12525
                     /gene="ppiB"
                     /locus_tag="ACHY1N_003123"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HFS4045397.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     VDNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
                     TVSE"
     gene            12528..13250
                     /gene="lpxH"
                     /locus_tag="ACHY1N_003124"
     CDS             12528..13250
                     /gene="lpxH"
                     /locus_tag="ACHY1N_003124"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008758 - UDP-2,3-diacylglucosamine
                     hydrolase activity [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HFS4045398.1"
                     /translation="MATLFIADLHLCVEEPAITAGFLRFLAGEARKAEALYILGDLFE
                     AWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKV
                     LELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANS
                     KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGA
                     WHTEGSMVKVTADDVELIHFPF"
     gene            13368..13877
                     /gene="purE"
                     /locus_tag="ACHY1N_003125"
     CDS             13368..13877
                     /gene="purE"
                     /locus_tag="ACHY1N_003125"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFS4045399.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSA
                     HRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVL
                     ENPDPRGAA"
     gene            13874..14941
                     /gene="purK"
                     /locus_tag="ACHY1N_003126"
     CDS             13874..14941
                     /gene="purK"
                     /locus_tag="ACHY1N_003126"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706400.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFS4045400.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQS
                     VITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAD
                     RSEWPAVFERLGELAIVKRRTGGYDGRGQWRLRANETEQLPAECYGECIVEQGINFSG
                     EVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELG
                     YVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVV
                     NSPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEA
                     LIPLLPPEYASGVMWAQSKFS"
     gene            complement(15078..15971)
                     /gene="ybcF"
                     /locus_tag="ACHY1N_003127"
     CDS             complement(15078..15971)
                     /gene="ybcF"
                     /locus_tag="ACHY1N_003127"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFS4045401.1"
                     /translation="MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKEVDPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVT
                     TVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQKALEAAYGWQMKRDGKYLRRVVASPQP
                     RKILDSEAIELLLKEGHVVICSGGGGVPVTEDGAGSEAVIDKDLAAALLAEQINADGL
                     VILTDADAVYENWGTPQQRAIRHATPDELAPFAKAYGSMGPKVTAVSGYVRSRGKPAW
                     IGALSRIEETLAGEAGTCISL"
     gene            complement(15968..16783)
                     /gene="ylbF"
                     /locus_tag="ACHY1N_003128"
     CDS             complement(15968..16783)
                     /gene="ylbF"
                     /locus_tag="ACHY1N_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HFS4045402.1"
                     /translation="MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHR
                     QGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPP
                     SHPQPLAAAWMQRAEETGLFGPLAMAASDPLTAELRQFRHCFQAALNGVKTDWRHWLG
                     KGPGLTPSHDDTLSGMLLAAWYYGALDARSGRQFFACSDNLQLVTTAVSVSYLRYAAQ
                     GYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGTP"
     gene            complement(16794..18053)
                     /gene="ylbE"
                     /locus_tag="ACHY1N_003129"
     CDS             complement(16794..18053)
                     /gene="ylbE"
                     /locus_tag="ACHY1N_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009029994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HFS4045403.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLH
                     AGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
                     AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFT
                     APVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAR
                     AVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGIG"
     gene            complement(18063..19730)
                     /gene="fdrA"
                     /locus_tag="ACHY1N_003130"
     CDS             complement(18063..19730)
                     /gene="fdrA"
                     /locus_tag="ACHY1N_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HFS4045404.1"
                     /translation="MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKA
                     LLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQSL
                     TQVRRWDSACQKLSDASLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLK
                     TRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEMLAFVSKPPAEAVRLKIVNAMK
                     ATGKPTVALFLGYTPAVACDENVWFASSLDEAARLACLLSRVTARRNAITPASSGFIC
                     GLYTGGTLAAEAAGLLAGHLGVEADDTHHHGMMLDADGHQIIDLGDDFYTVGRPHPMI
                     DPALRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYA
                     IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIRPLSPATQQHTPSLL
                     ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ"
     gene            20047..21096
                     /gene="allD"
                     /locus_tag="ACHY1N_003131"
     CDS             20047..21096
                     /gene="allD"
                     /locus_tag="ACHY1N_003131"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HFS4045405.1"
                     /translation="MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQ
                     QNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLA
                     FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALL
                     PAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSS
                     ELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISD
                     ALYNTSYETKNPFAQ"
     gene            21118..22353
                     /gene="allC"
                     /locus_tag="ACHY1N_003132"
     CDS             21118..22353
                     /gene="allC"
                     /locus_tag="ACHY1N_003132"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047652 - allantoate deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0000256 - allantoin catabolic process
                     [Evidence IEA];
                     GO_process: GO:0009442 - allantoin assimilation pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HFS4045406.1"
                     /translation="MITHFRQAIEETLPWLSSFGADPTGGMTRLLYSPEWLETQQQFK
                     KRMAASGLETRFDEVGNLYGRLNGTEYPQEVILSGSHIDTVVNGGNLDGQFGALAAWL
                     AIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
                     FVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVYAFSRICHQSIEKAKKMGDPLVLTFGKVEPRPNTVNV
                     VPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDICIDIDLWMDEEPVPMNKDL
                     VATLTELCESEKLNYWVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITD
                     LAEGVKTLALMLYQLAWQK"
     gene            22364..23149
                     /gene="allE"
                     /locus_tag="ACHY1N_003133"
     CDS             22364..23149
                     /gene="allE"
                     /locus_tag="ACHY1N_003133"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071522 - ureidoglycine aminohydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0010136 - ureide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HFS4045407.1"
                     /translation="MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFEN
                     CDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFA
                     LSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGHAPWLVSGNASELERIHYE
                     GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI"
     gene            complement(23278..24423)
                     /gene="glxK"
                     /locus_tag="ACHY1N_003134"
     CDS             complement(23278..24423)
                     /gene="glxK"
                     /locus_tag="ACHY1N_003134"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HFS4045408.1"
                     /translation="MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADG
                     GEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPE
                     KRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQV
                     LAANGGNLARVASIEMEECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEM
                     VEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAV
                     NLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVH
                     QYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN"
     gene            complement(24445..25746)
                     /gene="ybbY"
                     /locus_tag="ACHY1N_003135"
     CDS             complement(24445..25746)
                     /gene="ybbY"
                     /locus_tag="ACHY1N_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HFS4045409.1"
                     /translation="MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLL
                     TLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATS
                     LAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
                     IADPNFKIQLPPFALSVAVMCLVLGMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSH
                     SLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTR
                     YRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVP
                     ALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMA
                     LPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE"
     gene            complement(25803..27104)
                     /gene="allB"
                     /locus_tag="ACHY1N_003136"
     CDS             complement(25803..27104)
                     /gene="allB"
                     /locus_tag="ACHY1N_003136"
                     /EC_number="3.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004038 - allantoinase activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0050897 - cobalt ion binding [Evidence
                     IEA];
                     GO_process: GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HFS4045410.1"
                     /translation="MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVM
                     DASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFFKGAQKLGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRL
                     HVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLEN
                     QKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMEAWGGIAGLQNCMDVMFDEAVQKRG
                     MSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSP
                     YVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ"
     gene            complement(27164..28618)
                     /gene="ybbW"
                     /locus_tag="ACHY1N_003137"
     CDS             complement(27164..28618)
                     /gene="ybbW"
                     /locus_tag="ACHY1N_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
                     /protein_id="HFS4045411.1"
                     /translation="MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVP
                     NYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYGVR
                     GALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
                     TFLLFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGLGPIFDYIPSG
                     IQKAENSGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFA
                     VAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAG
                     YQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMM
                     AHYFVVMRGQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIPFMEPLS
                     RVSWFVGVIVAFAAYALLKKRTTAEKTGEQKTIG"
     gene            complement(28788..29666)
                     /gene="glxR"
                     /locus_tag="ACHY1N_003138"
     CDS             complement(28788..29666)
                     /gene="glxR"
                     /locus_tag="ACHY1N_003138"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008679 - 2-hydroxy-3-oxopropionate
                     reductase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046487 - glyoxylate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HFS4045412.1"
                     /translation="MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     SVETARQVTEASDIIFIMVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKR
                     FARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SALVQALELMANHKLA"
     gene            complement(29766..30542)
                     /gene="hyi"
                     /locus_tag="ACHY1N_003139"
     CDS             complement(29766..30542)
                     /gene="hyi"
                     /locus_tag="ACHY1N_003139"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HFS4045413.1"
                     /translation="MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEE
                     LKQVLASNKLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPAGFSSEQIHATLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
                     ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGE
                     INYDYLFKVIENSDYNGWVGCEYTPKTTTEAGLRWMDPYR"
     gene            complement(30555..32336)
                     /gene="gcl"
                     /locus_tag="ACHY1N_003140"
     CDS             complement(30555..32336)
                     /gene="gcl"
                     /locus_tag="ACHY1N_003140"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009028 - tartronate-semialdehyde synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HFS4045414.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAKRPVIVAGGGVINAD
                     AAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQ
                     EMQKAGRLPCRKEWVAECQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPERKVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSE
                     LDNVMEFEDIADNAADAPTETCFMHYE"
     gene            complement(32426..33241)
                     /gene="allR"
                     /locus_tag="ACHY1N_003141"
     CDS             complement(32426..33241)
                     /gene="allR"
                     /locus_tag="ACHY1N_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HFS4045415.1"
                     /translation="MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVS
                     DISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVA
                     GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCI
                     ASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHP"
     gene            complement(33319..33801)
                     /gene="allA"
                     /locus_tag="ACHY1N_003142"
     CDS             complement(33319..33801)
                     /gene="allA"
                     /locus_tag="ACHY1N_003142"
                     /EC_number="4.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HFS4045416.1"
                     /translation="MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALV
                     EILEQDRTLISINRAQPANLPLTIYELERHPLGTQAFIPMKGEVFVVVVALGDDKPDL
                     STLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
                     "
     gene            34031..34957
                     /gene="allS"
                     /locus_tag="ACHY1N_003143"
     CDS             34031..34957
                     /gene="allS"
                     /locus_tag="ACHY1N_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HFS4045417.1"
                     /translation="MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENT
                     GVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMPSELQQVNDGVERQVNIVINNLL
                     YHPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
                     LDPFGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFLPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKF
                     GSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS"
     gene            35026..36120
                     /gene="mnmH"
                     /locus_tag="ACHY1N_003144"
     CDS             35026..36120
                     /gene="mnmH"
                     /locus_tag="ACHY1N_003144"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043828 - tRNA 2-selenouridine synthase
                     activity [Evidence IEA];
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HFS4045418.1"
                     /translation="MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMN
                     NDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQ
                     RSHIVQSWLYAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQ
                     QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQDLRLWVLEDES
                     RMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQ
                     EYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYD
                     PMYRYQLEKKAEKVVFRGEWAEVAEWVKAR"
     gene            36236..36601
                     /gene="ylbG"
                     /locus_tag="ACHY1N_003145"
                     /pseudo
     CDS             36236..36601
                     /gene="ylbG"
                     /locus_tag="ACHY1N_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014543172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(37367..37561)
                     /locus_tag="ACHY1N_003146"
                     /pseudo
     CDS             complement(37367..37561)
                     /locus_tag="ACHY1N_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308588.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         9674 a         9792 c         9062 g         9040 t
ORIGIN      
        1 agaggttcga gacgatattg agcgccgtgc ttatgaaatc gcactcgtat ctctggaagt
       61 agagccagat gaacgcgaag cctatgaatt attcatggaa aagcgtttcg gtgacttagt
      121 agatcgtcgg agagcaaaaa acggcgataa cgaatacatg gcatgggata tgactctcgg
      181 ttggatcgtc tggcagcaac gagctggtat ccatttttca acaatgtcac agcaagaggt
      241 gaaataatgg agccatacag cctcacactc gatgaggcct gtcattttct caaaatatcc
      301 agaccgactg ccattaactg gatacgcaca ggccgcctac aggcaacacg taaagatcca
      361 accaagccaa aatctcctta cctcacaaca cggcaagctt gcattgcggc gcttcagtct
      421 ccgctgcata ctgtccaggt gagcgcgggt gatggcataa cagaggaaag aaaatgtcac
      481 tcttccgcag aaatgaaata tggtatgcct cgtattcgct cccgggcggg aaacgaatta
      541 aggaatctct tggcacaaag gacaagcggc aagctcagga gttgcacgac aagcgaaaag
      601 cagaactctg gcgagtagaa aagctagggg atttacctga tgtcactttt gaagaggcct
      661 gcctaagatg gcttgaggaa aaagctgata aaaaatctct cgattcagat aaaagccgga
      721 ttgagttctg gcttgaacat tttgagggta taaggcttaa agatatctcg gaggcaaaga
      781 tttactctgc tgtaagcaga atgcataaca gaaagacgaa agaaatatgg aaacagaaag
      841 ttcaggccgc catcaggaaa ggtaaagaac cgcctgttta tgaaccaaag ccagtatcaa
      901 ctcagacaaa ggcaaagcat cttgccatga taaaggccat tctccgtgct gcagaacgcg
      961 actggaagtg gctggaaaaa gcgcctgtca tcaagatacc agcggtcaga aacaagcgag
     1021 tcagatggct ggaaaaggag gaagcaaaac gccttattga tgagtgcccc gaaccactga
     1081 aatctgtcgt caagtttgcg ctggcaactg gtctgagaaa gtcgaacatc ataaatctgg
     1141 aatggcaaca aatcgacatg cagcgacgag ttgcctgggt gaatccagaa gagagcaaat
     1201 caaaccgcgc cattggtgtg gcgctgaacg ataccgcctg taaagtgttg cgtgatcaaa
     1261 taggcaagca tcacaaatgg gtgtttgtac ataccaaggc ggctaagcga gcagatggaa
     1321 catcaacgcc tgcggtcagg aagatgcgca tcgacagcaa gacatcatgg ctatcagctt
     1381 gtcgtcgtgc aggaattgaa gatttccgtt tccatgacct cagacacacc tgggcaagct
     1441 ggctgatcca gtcaggcgtc ccattatctg tgcttcagga aatgggcgga tgggagtcca
     1501 tagaaatggt tcgtaggtat gctcaccttg cgcctaatca tttgacagag catgcaagga
     1561 aaatagacga catttttggt gataatgtcc caaatatgtc ccactgtgga attatggagg
     1621 atataaagaa ggcgtaactg attgaattgt aatggcgcgc cctgcaggat tcgaacctgc
     1681 ggcccacgac ttagaaggtc gttgctctat ccaactgagc taagggcgcg ttgataccgc
     1741 aatgcggtgt aatcgcgtga attatacggt caacccttgc tgagtcaatg gcttttgatc
     1801 tggttgctga acaagtgaac gaccgcgtct gattttctga tttatttcgc tatagcggca
     1861 aacaaacaca caccgctgcg cgtctgaatc aagaaaaccc gtattttcat gtatcaaagt
     1921 acaatttacc gccctaacgg aaaattgtcc gctcctatga gactggtaac tatgaaacca
     1981 acgtcggtga tcattatgga tactcatcct atcatcagaa tgtctattga agttctgttg
     2041 caaaaaaaca gtgaattgca gattgtcctg aaaacggatg attaccgcat aaccatcgat
     2101 tatctccgaa cccgtcctgt tgatttaatc attatggata tagacttgcc cggaacagac
     2161 ggttttacct tcctgaaaag gatcaaacaa atccagagca cagtgaaagt gttattttta
     2221 tcatcgaaat cagaatgctt ttatgctggc agagcgatac aagctggtgc taacggtttt
     2281 gtcagtaaat gcaatgatca gaatgatatt tttcatgccg ttcagatgat cctctccgga
     2341 tacacgtttt ttcccagcga aacgcttaac tatataaaaa gcaataaatg tagtacgaat
     2401 agttcaacgg tcactgtgct atctaatcgt gaagtgacca tattacgtta tctggttagc
     2461 ggattatcta ataaagaaat tgccgataag ttattactta gcaataaaac agttagtgcg
     2521 cataaatcta atatttatgg caagctaggt ttgcattcaa ttgtagagct tatcgactac
     2581 gccaaattat acgaattaat ataatattaa ttataattga tcataaatat cgcatccgct
     2641 ttcgccacac ctggccgaac accgctggct aacgctcgat aattggcaaa aaagtttagt
     2701 gtgacattgc catttgcatc tacttcctca gtcgggctcg ccgctcccag tgcgagccgg
     2761 gagcgatcgc tattacgtaa ttcgatggcg atggtttgcg ccattgcggg atcatccaga
     2821 gccagcaggt tggtatcgga tgccggcgtt cccgtaaata aaatcgcaac tgaacccgga
     2881 ggacatccct ccagccgcag gctaaaaggg acgagtgccg tggtatcgcc agcgttcagt
     2941 aattgtgtcg taggccatct gcctaaatct accgtcttat caatatccgc agtgtttacg
     3001 gtacaggaga aatcaacaac gttaccgtgc aaattgatat taatcgttcc caaagggtca
     3061 gctgcccatc cactggaaat ccacagtaac ccgcagaaac agctaaagag tgctcttctc
     3121 attctccgta cctcattgat aatcgacgcg taaatacccc agcgcgctaa acggcccttc
     3181 ggtcggtttt tgaccggtaa tactgatagg ccaggcgcga agtgtgacat tggctgccgc
     3241 agctgcatcc agacggaaag gaataacgct attgagatcg ttaggcgtga tcggcgtatc
     3301 gttctgatcg gcgacaataa aacctaaatc ctgattgtcc gacaccatcg cctgaccaga
     3361 aacggcactg gcttccagac gcattgttaa ataagcctgc gcagcaacat tcgtacattt
     3421 gaccgcaatg ctcttggttt gcggcatgac accagcaggt cgattacccg gccctgccgc
     3481 actaaataac gatgcgccga tatcaccaaa atcaaattca acaatctgcc cggcatttaa
     3541 ttcgcagttt tgcggtactt caacccggcc accaaaacta atggtataaa caggtgtaac
     3601 caacggatcg taaggcgttg atgtcacata cacggtaaac atcacctgtc tggggatctc
     3661 caccatgtta ataaagggac gaataacctt taaacgaaat attaaacgag aatccatcac
     3721 cccgaatgga aggttttgcg aaacgttagg atctgttccc atcagaatat aattttgcgg
     3781 ggggaactga atatccatca cactatcaac cagactcatc gcacctaata gataatcatt
     3841 taattgcata tatttataat tatcgatagt ttcctgaaca ataaagttgg tgacataact
     3901 acggtatgta taattcacca gcgtaccggg tggacaaatt gctgagacac ctacccagcc
     3961 ggatttttcc ggtaaaacaa caatctgccc tggctggtta ttggtgctat taaagatatt
     4021 tgagagatca tagtgttcat cttctgctac gccagtacta tttgcacaaa cagtagccca
     4081 ggatatgttt gccagacaca aacatgccat cgccaataat aatctgcaga ttatcttcat
     4141 tgataatttc ctttatgagc caggatgtgt gcaaactgcc gaaataacag tgacggcttg
     4201 ctgtaagctt tgcttcggca atacatagtg cgcaatgcag cgtgagttcg cgccgtctcc
     4261 ccactgaacc agtaattcac cagacaatgg cgcaccactt aaataaactt gcccgtcatc
     4321 acccacatac tggttattcc gatactgttt tcccgtacca gtgatccaaa cggcaccggt
     4381 tttccgccct gggtaacggt aatgagcgcc cgcacgccta tgcgggtatc aaaattggca
     4441 cgaaccaacg cgccttgcgt cggcacaacg ctgctaatat ttttttcaac atcgatggaa
     4501 ttccccatcg tattggtatc aagcgcgata cggttatacc gataaaccgt ggcatacggc
     4561 atcaccgcat agccgcgcca gtcggttaaa atgccagttt gattttcaat gcgtacaccg
     4621 cctgcgccag gcgctttaat caaaacattg gtatccccta aaggctggct cagcgttatg
     4681 ccattttcat gcccgaccac accgccagac agctgccagt taacgtcatg ttgatcgcgg
     4741 tcgtagttat acccgacccc cagcgtagcg taagcggcct gccagtttgc cgtggcgctg
     4801 cccgtatacc cattattcga ggtatcaccc tggcttacgt gataactcag gttgtggcct
     4861 tccagtaagg tcccacctac acctgccagc cagctatttt gcccgttgct gttacggttg
     4921 gcgttaaagg aggcataagc gcggtcgagc gcattttccc gggtgtagcg acgtttggtc
     4981 agaacattga aaggcactga aacattaagt ccgacaatac gttcgttatc ggggatccct
     5041 acagattcat tccacgaaaa tgagagtgaa taactgatgc caacccagct gctggtatac
     5101 cccacctgat accaggtatc tgaatccgaa gtattccagt atttttgatg ggtaccagag
     5161 atataaagcg agccaaagtc attaagtgat tgtgaaatat ttaactgcaa acggtcttta
     5221 cggctaaagc gtaaattgtg gtaattcacg attatcggtt catcccgatg ctcaccgtcg
     5281 taatcgtaat catattcgta cccctccatt cgacgatacg caacatcatc aagggtataa
     5341 aaaccttgtg tcgaatagcg gtaacccatt aactgaaaat tggtgccgaa ggtgttcatc
     5401 gatttcgcat agaggaagcg aatggaatcc ccctcatgac gactgtcgtc ggctaactga
     5461 ctgcgcgcat gggtcacatc cagcgacact gccccccagt ttccgagatt gcgccccagt
     5521 cctaataaaa aggcggtgta attggcagat aattgcgtcc cgccgtaggc agtaaattcc
     5581 tgtggtaaac cgccgagtgc cgtgccctga aaaaagaaag gcgatgattg ctgactatta
     5641 ccgctacgaa aatcgcccgc cgtcaggtca aatttgaaac gcccttcgcg ttgtaaaatt
     5701 ggcactgttg aatacgggat agtgtaattc tgctgattac catcgcgctc gtcgatggtg
     5761 acgtccagat cgccatttga agatgtcggg tgcaaatctg taatttcaaa agcgccgggg
     5821 gaaacatagc tttgatagat aataaaacca ttttgccgaa tcgttagctg ggccgccgta
     5881 cgggcaatcc cacgtaccgt tggggcaaac ccttgctggc tatcaggata catattatcg
     5941 gaagaataaa gccgtacacc acgaaatcca acaccatcga aaatatcact tcctgtattg
     6001 ccgtctccca ttaccagttc acttttcagc ggaataatgg cgcgctgtac ccaggtgcca
     6061 atattattcc actgttctga atgatatcca tttccgcgaa aatagttcca ggaaccattg
     6121 ttgcgtaaac gccacgggcc aatattaatc ccgctgagct cactaaaaaa atagctatcg
     6181 ttaccattac ctctgttacc ggtgaaatta taattcagga gtaaagcagg aataccttca
     6241 tcccactctt caggcggaat gtaaccgtga gcgctactca acaacgttat ctgaggaata
     6301 gtgatgttca ggcgcatcgc tgcaaaatca aagttaattg tggcatcagg tacagctttc
     6361 agtaaattga tgcatttatt gttttgctgc tgggctaact cgggaaatgc actgctatta
     6421 aggccaattc gttcaaggag tacctggtta aaacagggca ttaacccacc tgatttatca
     6481 cctgtatttt ctgttgtcga ttcaaatacg atatcctgtg aaccaatgaa ctcatcatta
     6541 cgccagagat ccacccgata cactcccgca ggttgatgat tgcctctctc aaagcgcgat
     6601 aaatcagcaa cggatgtgcc attctctaat aaaaatgccg ggttgaaata actttccgca
     6661 tagcttaaaa aggagagtaa aatggcaaga gatgaataac aaattccggc cagacaccag
     6721 gtatacctct gcggaatatc cgtagtagtg ggtattttca taattagctc tgatattgtc
     6781 agatgattcg gttagtttaa gttcacttct ctgaccgggg ttactgaacc ataatcatta
     6841 acggtctgaa atttcagctt tccctgcact cctgagggta agggaatttg tgaactaact
     6901 ctgggtgccg ccatagcatt ccccaacttt tggctgccca cttgcaggtt aacgagggtg
     6961 acataaaaag gtgatggatt atgaacattg atatagttac cggatcgcga aaacttgagt
     7021 gtgtccggcg cttctgcggg taattcttgt aattgaattg gacggagaaa taatttcatg
     7081 cgcgataaaa tcgccagttg caaaacattc ctgccgttca atgcattttt atctaccgaa
     7141 gggatcgtct taacattcat ccagaacaga gactcacgat ctgctgccag cggtggaccg
     7201 gtgtaaataa tacgcaaagt attttcgctt ttgggttcac taacaaacag tggcggtgta
     7261 atgatgaatg acttttcttt tacaccgctg ctgttttcaa tccacgaatt gaccagaaaa
     7321 cgctcattgg tatggctatt tctaatccat accgcagtct gtttagcatc agcgggataa
     7381 ataatacgcg tggcacctaa tgcgatccct ccggcagcat gggcgctggc cgaaatgatt
     7441 aaataaaata taatgagcat caataacttt attttagtca tcatagttaa tacgccttgt
     7501 gtattcctga cggcaaaaat aagaaatata aagaaatgat tgctttggtt tcttacaaca
     7561 catcattccc ttttcattta ataaagcggc atgatacaaa gtgaacatga tttcgattta
     7621 cattgccacc ataccgcttc agacaaccgg tacattactt tgttataaga cgtgatatat
     7681 aattcaaaac aacgtggttt tgattattcg tatctcataa taaaagtcgc gtcagcattt
     7741 gcttgccctg ctgatgcact tgtaccggtg cctttataac gtgcagaaaa atgaagaacg
     7801 ttggttccgg ggatcaagtt ctggttggtt gagaagctat tcccatcagg tttgagaatt
     7861 gcggatgtat tatcaagtat ttcaataccg acacccgttg ctgttgttgt attggtactg
     7921 gatgcaatgg ccaataaatt atcattgatt gcatcagcct gaccagaaaa tgcaacggca
     7981 gcattagcgg caacaacagg atcgcagtcg ttcaactgaa tggtgaatgg aattaatgca
     8041 gaggtattac caacagcatt gaaaatatcg gtacgatatt gaccgagtgt gacaacctgg
     8101 tctgccgagt cagtattcac tgaacaggca gcattcacca gttcgccttc aaagtgaatt
     8161 gtaccgccat ctacaacggc agcataacta cccgtagcgg cgaatagtgc ggcagccagc
     8221 gcagacgaaa taaatcttaa tttcatatat attccttcaa tctcatttat cgactccaca
     8281 tccgtatata accgattact ttatttaaga cactgatagt agtaaaattc ctttttatcc
     8341 tctaagaatg tcttaattga aaatatgcac tctattctaa aaaatagaga gccccgttag
     8401 atgaatactt ccgcgcaaaa tatattcaac aaaaatatag acctgaagcg gtaaattacc
     8461 aggctgaaaa ttctttttat attgtcaggt atttcttaaa ttatcttaat ccttaaacaa
     8521 ggaaataaat cagttccaga tttacaacgc catcatggac gaaaaatgaa gctttcaatc
     8581 tcagcgacct cagcgacggt gcgcctaacc ttcgcaagag gtcgcttcac gcgataaatc
     8641 tgaaacgaaa cctgacagcg cgccccgctt ctgacaaaat agacgcatcc ccttcgacct
     8701 acgtaacaga tggaatcctc tctctgatgg cagcaaagat tattgacggt aaaacgattg
     8761 cgcagcaggt gcgctctgaa gttgctcaaa aagttcaggc gcgtattgca gccggactgc
     8821 gggcaccagg actggccgtt gtgctggtgg gtagtaaccc tgcatcgcaa atttatgtcg
     8881 caagcaaacg caaggcttgt gaagaagtcg ggttcgtctc ccgctcttat gacctcccgg
     8941 aaaccaccag cgaagcggag ctgctggagc ttatcgatac gctgaatgcc gacaacacca
     9001 tcgatggcat tctggttcaa ctgccgttac cggcgggtat tgataacgtc aaagtgctgg
     9061 aacgtattca tccggacaaa gacgtggacg gtttccatcc ttacaacgtc ggtcgtctgt
     9121 gccagcgcgc gccgcgtctg cgtccctgca ccccgcgcgg tatcgtcacg ctgcttgagc
     9181 gttacaacat tgataccttc ggcctcaacg ccgtggtgat tggcgcatcg aatatcgtcg
     9241 gtcgcccaat gagcatggaa ctgttgctcg caggttgcac cactaccgtg actcaccgct
     9301 tcactaaaaa tctgcgtcat cacgtagaaa atgccgatct gttgatcgtt gccgttggca
     9361 agccaggctt tattcccggt gactggatca aagaaggcgc aattgtgatt gatgtcggca
     9421 tcaaccgtct ggaaaatggc aaagttgtgg gcgacgtcgt gtttgaagac gcggctaaac
     9481 gcgcctcata cattacgcct gttcccggcg gcgttggccc gatgacggtt gccacgctga
     9541 ttgaaaacac gctacaggcg tgcgttgaat atcatgatcc acaggatgag taacatggcg
     9601 acattttctt taggtaaaca tccgcacgtt gagctgtgcg acttgctgaa actggaaggc
     9661 tggagcgaaa gcggcgcgca ggcgaaaatc gcgattgccg aaggccaggt gaaagtcgac
     9721 ggtgcggttg aaacgcgcaa acgctgcaaa atcgtcgccg gtcagacagt gagttttgca
     9781 ggtcacagcg tacaggttgt tgcctgatcc ctttcccggc ctgtatcaac aggccggttc
     9841 tcttttcaga cttttgccct ctacgccccg ttcatccatg ctgatagcat cgacattttg
     9901 ccgaagcgac catcatgcca accgttatta cgcacgccgc cgttccccta tgcattggtt
     9961 tagggttggg ttcgaaagtc atccctccgc gtctgttatt tgccggaatc atcctggcga
    10021 tgctgcccga cgccgacgta ttgtcgttta aatttggcgt tgcttacggc aatgtttttg
    10081 gtcatcgcgg gtttacccat tcgctggtgt ttgcgtttgt tgtcccgctg ttatgtgtgc
    10141 tgattggacg ccgatggttc agggctgggc tgattcgctg ctggctgttt ttaaccgtct
    10201 cgttgctatc gcacagcttg ctggattcgg taaccactgg cggtaagggc gttggctggc
    10261 tgtggccgtg gtcagatgaa cgctttttcg ctccctggca ggtgattaaa gtcgcgccgt
    10321 ttgcattgtc tcgttacacc acgccgtacg ggcatcaggt gataatttct gaattgatgt
    10381 gggtgtggtt gccggggatg gtgcttatgg gaatgttgtg gtggcgcagg cgataaccgg
    10441 atgcgaaaac tcgcatccgg caacagcgca attacttacg acgccaggtg gtcccttgcg
    10501 ggccatcttc cagcacgatc cccatctcgt taagacggtc acgcgccgca tctgccgccg
    10561 cccagtcttt cgctttacgg gcatccagac gctgttgaat taacgcttca atctcagcca
    10621 cttcgctgtc gtctgcctgc gcgccgcttt gcaggaacgc ttccggttct tgctccagca
    10681 ggcccaatac agcggaaagt ttacgcaggt gagatgccat tgcattcgcc gctgccatat
    10741 cttctgcttt cagacggttt acttcacgcg ccatatcaaa cagtacggaa taggcttccg
    10801 gggtgttgaa atcgtcgtcc atcgcttcaa taaagcgcgc ttcaaacgct tcgccaccgg
    10861 caggcgcaac ggttttatct gtgccgcgca gcgcagtgta gagacgctcc agcgccgcac
    10921 gcgcctgctt caggttctct tcgctgtagt tcaactggct gcgatagtgg cccgacatca
    10981 ggaagtaacg cacggtttcc gcgtcgtagt atttcagcac atcgcgcacg gtaaagaagt
    11041 tacccagcga tttggacatc ttctcgcggt caaccatcac catccccgag tgcatccagt
    11101 agttcacata ctggccatca tgggcacagg tggactgcgc gatttcgttc tcgtggtgcg
    11161 ggaacatcag gtctgaaccg ccgccgtgga tatcaaagtg gttacccagc tgcttgcagt
    11221 tcattgccga acattcaatg tgccagcctg gacggcccgc gccccacgga gacggccagc
    11281 tcggttcgcc ctctttcgac atcttccaca gaacgaagtc catcgggttg cgtttgtcgt
    11341 cgaccacgtc aacgcgcgca cctgcctgca gctggtcgag atcctgacgc gacagcacgc
    11401 catatgtcgg atcggtcggg acgtcgaaca tcacgtcgcc gttgtccgcc acataagcgt
    11461 gacctttggc gatcagttgt tcagtgagtt caataatttc tgcgatatgg tgcgtcgcgc
    11521 gcggctccat atccgggcgc agaatgttca aagcatcaaa atctttgtgc atttcggcga
    11581 tcatgcgatc caccagcgcc acaaagcttt cgccattttc attggcgcgt ttgatgattt
    11641 tgtcgtcgat atcggtaatg ttgcgcacat acttcagttt atagccgagg aaacgcagat
    11701 agcgcgcaac cacgtcaaaa gcaacaaagg tacgcccgtg accgatatga cagagatcgt
    11761 aaacggtgat tccacacaca tacatgccga cttccccggc gtgaataggc ttaaattcct
    11821 ctttttggcg tgtcagagta ttgaagattt ttagcatcga agattccgtt tagacatgtg
    11881 tgggtaattg agttgcgtat aatacccata tttcccgcgc gaatcagcat acattgcgtg
    11941 atgatccgat cgtgcggtta tgctataaca ccaccctata tatgacccga actgggttga
    12001 agcaccaatc aaacggaaca ggatgcaaaa atggttactt tccacaccaa tcacggcgat
    12061 attgtcatca aaacttttga cgataaagca cctgaaacag ttaaaaactt cctggactac
    12121 tgccgcgaag gtttttacaa caacaccatt ttccaccgtg ttatcaacgg ctttatgatt
    12181 cagggcggcg gttttgaacc gggcatgaaa caaaaagcca ccaaagaacc gatcaaaaac
    12241 gaagccaaca acggtctgaa aaatacccgt ggtacgctgg caatggcccg tactcaggct
    12301 ccgcactctg caactgcaca gttcttcatc aacgtggttg ataacgactt cctgaacttc
    12361 tctggcgaaa gcctgcaagg ttggggctac tgcgtgtttg ctgaagtggt tgaaggcatg
    12421 gacgtggtag acaaaatcaa aggtgttgca accggtcgta gcggtatgca ccaggacgtg
    12481 ccaaaagaag acgttatcat tgaaagcgtg accgttagcg agtaatcgtg gcgacactct
    12541 ttattgcaga tcttcatctc tgcgtggaag aaccggcgat caccgccggt tttctgcgtt
    12601 ttttagcggg ggaagcccgc aaggccgaag cgctgtatat tcttggcgat ctgtttgaag
    12661 catggattgg cgacgacgat cccaacccac tccatcgcca gatggcggca gcgatcaaag
    12721 cggtgtccga ttccggcgtt ccctgttatt tcattcatgg caaccgtgat tttctgctcg
    12781 gcaaacgctt tgcccgtgaa agcggcatga cattattgcc ggaagaaaag gtgctcgaac
    12841 tttatggtcg ccgggtgttg attatgcatg gcgacacgct gtgcaccgat gacgcgggtt
    12901 atcaggcttt tcgcgccaaa gtccacaaac cctggctgca aatgctattc ctcgccctgc
    12961 cgttgtttgt gcgcaaacgc attgccgcgc gaatgcgagc gaacagtaaa gaagccaaca
    13021 gcagtaaatc gctggcgatc atggacgtta accaaaacgc ggtagtcagt gcgatggaaa
    13081 aacatcaggt gcaatggctg atccacggac atacccatcg cccggcggta catgaactta
    13141 tcgccaacca gcaacctgct tttcgcgtgg tactcggtgc ctggcatacg gaaggttcga
    13201 tggtgaaagt cacggcggat gacgttgagc tgattcattt tccgttttaa aaaacccgca
    13261 actttgctga tttcacagcc acgcaaccgt tttccttgct ctctttccgt gctattctct
    13321 gtgccctcta aagccgagag ttgtgcacca caggagtttt aagacgcatg tcttcccgca
    13381 ataatccggc gcgtgtcgcc atcgtgatgg ggtccaaaag cgactgggct accatgcagt
    13441 tcgccgccga aatcttcgaa atcctgaatg tcccgcacca cgttgaagtg gtttctgctc
    13501 accgcacccc cgataagctg ttcagcttcg ccgaaagcgc cgaagagaac ggttatcagg
    13561 tgattattgc gggcgcaggc ggcgcagcgc acctgcctgg tatgattgcc gccaaaacgc
    13621 tggtgccagt gctgggcgtg ccagtacaga gcgccgcact gagcggtgtc gatagcctct
    13681 actccatcgt acaaatgccg cgcggcattc cggtgggtac gctggcgatt ggtaaagctg
    13741 gcgcggcaaa cgcggcgtta ctggcagcac aaattcttgc gactcatgat aaagaactgc
    13801 accagcgtct gaatgactgg cgcaaagccc agaccgacga agtgctggaa aacccggacc
    13861 cgcgaggtgc ggcatgaaac aggtttgcgt cctcggtaac gggcagttag gccgtatgct
    13921 gcgccaggca ggtgaaccgt taggcattgc tgtctggccg gtcgggctgg acgctgaacc
    13981 ggcggcggtg ccttttcaac aaagcgtgat taccgctgag atcgaacgct ggccggaaac
    14041 cgcattaacc cgcgagctgg cgcgtcatcc ggcctttgtg aaccgcgatg tgttcccgat
    14101 tattgccgac cgtctgactc agaagcagct tttcgataag ctccacctgc cgaccgcacc
    14161 gtggcagtta cttgccgatc gcagcgagtg gcctgcggtg tttgagcgtt taggtgaact
    14221 ggcgattgtt aagcgtcgca ctggtggcta tgacggtcgc ggtcaatggc gtttacgtgc
    14281 caatgaaacc gaacagttac cggcagagtg ttacggcgaa tgtattgtcg agcagggcat
    14341 taacttctct ggtgaagtgt cgctggttgg cgcacgcgga tttgatggca gcaccgtgtt
    14401 ttatccgctg acgcataacc tgcatcagga cggtattttg cgcaccagcg tcgcttttcc
    14461 gcaggccaat gcgcagcagc aagcgcaagc cgaagagatg ctgtcggcga ttatgcagga
    14521 gctgggctat gtgggcgtga tggcgatgga gtgttttgtc accccgcaag gtctgctgat
    14581 caacgaactg gcaccgcgtg tgcataacag cggtcactgg acacaaaacg gtgccagcat
    14641 cagccagttt gagctgcatc tgcgggcgat taccgatctg ccgttaccgc aaccggtagt
    14701 gaatagtccg tcggtgatga tcaacctgat tggtagcgat gtgaattatg actggctgaa
    14761 actgccgctg gtgcatctgc actggtacga caaagaagtc cgtccggggc gtaaagtggg
    14821 gcatctgaat ttgaccgaca gcgacacatc gcgtctgacc gcgacgctgg aagccttgat
    14881 cccgctgctg ccgccggagt atgccagcgg cgtgatgtgg gcgcagagta agttcagtta
    14941 agcaggtgct catttgattg ccggatgcgg cgtaaacgcc ttatccggct taccgctccg
    15001 gtacccattg taggcctgat aagacgcgtc aagcgtcgca tcaggcatgg tgcaccgatt
    15061 gccggatgct ctcatcacta cagcgaaata caggtccccg cttcgcccgc cagcgtctct
    15121 tcaattcgcg ataacgcccc aatccacgcg ggtttaccac ggcttctgac ataaccactt
    15181 accgccgtta ccttcggccc catcgaacca taggctttgg caaatggcgc taactcatcc
    15241 ggtgtggcat ggcgaatggc gcgttgctgc ggcgttcccc agttttcata aaccgcgtca
    15301 gcatcggtga ggatcaccag tccatcggca ttaatctgct cggcgagcaa cgcagcggcg
    15361 agatctttat caatcaccgc ttcactccct gccccatctt ccgtcacagg cacaccgccg
    15421 ccgccactgc aaatcaccac atgcccctct ttgagcaaca actcgatggc ttcgctgtcg
    15481 agaattttac gcggttgcgg agacgccacc acccggcgca aatatttacc atcacgtttc
    15541 atctgccagc cgtaagccgc ttccagtgcc ttttgttctt ctggctgata aaccggacca
    15601 ataaatttct ctggctgcaa aaacgccgga tcatcaggcg aaacctcaat gcgcgtcagc
    15661 accgtcgtga caggcggcat ctgcggctgt gcgctcaaac tctgcgccag catatagcca
    15721 atcatcccct ggctttccgc caccagcaca tccagcggat acggatctac ctctttccac
    15781 gccagattct gcaatgccag cagccccacc tgcggcccat tgccgtgaac aatcgccagc
    15841 cgataagaac gggccaggcg cgccagcgcg ggtacagcac tggcgatatt gcgatattga
    15901 ttttctgccg tcagcgcctc accgcgctgg agtaaggcgt tgcccccaag agctacaacc
    15961 agtgttttca tggtgttcct tgtaataatt gttgaccaag ccagaacccc agcagcgtat
    16021 ctgcccctga cgtgtgcccc agcgccagca gcgaatcaat cgcaacagcg gtacgtttcg
    16081 ggcaactcag agcatgaaca aagtgcagga gtggcgaggc gaaatatcct tgcgcggcgt
    16141 agcgtaaata actgacgctc accgctgtgg taacgagttg aagattgtcg gagcaggcaa
    16201 aaaactggcg accggagcgc gcatctaaag cgccataata ccaggccgcc agcagcattc
    16261 cgctcaacgt gtcatcatga cttggcgtta atccggggcc tttacccagc cagtgccgcc
    16321 agtcggtctt aacgccattg agcgcggcct gaaaacagtg acgaaactgg cgtaattcag
    16381 cggtcagcgg atcgcttgcc gccatcgcca gtggtccgaa aagtccggtt tcctccgcgc
    16441 gttgcatcca tgcagctgca agcggttgag gatgtgaagg cggcgtaata cgcagcaaac
    16501 aataacgctg tggctgttta accgtgaaac gcccgaggcg aatcccttga gccacaacct
    16561 gtggtcgttc attgccgcat aatccaccgc ataacgcatc gaattgcgcg cggcgaagca
    16621 cccatcctcc ggggccgaaa ccactaccct gacgatgcag cgttaacagt tcgccgcttt
    16681 ccgtcatcag gttaatcgcc cgtcgccaca ctcccgctaa ccgccaggac tggcgataat
    16741 tcggtgcact acggctggca agcagaggat ggatgatcgt cattgcgcgt tcctcaacca
    16801 atccccatgc tttcagccag tgcttccagc gcctgttcaa aacacgccag cggtgcccgc
    16861 acagtgcctg cgccaatctg cccgatcccc gcctctttat gggcgatacc ggtattgatg
    16921 agtggcgtaa tgccggtttc taccacgcga cgaatgtcca gtcccaggca cgcgccctga
    16981 aaatcccagc ctgggatctg caactgcata ttgcgctcaa ggtaaatttc cgccatctct
    17041 tcagataccg ctctggccgc ttccatgcca cccgcaccga caaagcgcgt tacgccaggc
    17101 gctgcgatca ttgccgcacc tccgatacca aaggtttcgg taatcgcgct atcgcccata
    17161 tccgggttcg cctgctcctg cgagaagccg gtgaaaaaca gaccttgcgg agtgtttaca
    17221 ggcgcagtaa accagcgttc gcccagcccg cttacccgaa tcccgaacat attgccgttg
    17281 cgggtcattg ccgtgacgat gctgcctgca cggatcatcg cgccagcatc catcgccgcc
    17341 ttgcagtaag ccatcgcgag gttgaggaag aactgatcgg tcacgctgag gaaatccatc
    17401 acttcggcga tgtgctgttt atcatgatcg aggcgagcaa tttgtggggc cagcgcacgc
    17461 attaacagtg cagaggaagc aatattgcgt tgatggaact catcgcccat cgtaatgccc
    17521 tgcgccatca tcgccgtgag atcgataccg cgctccatgc gccccagcgc cgcgcttaat
    17581 actggcatta acacatcgcg catccagcga tggcgagtca ggacatcttc gccgtaagcg
    17641 ccaaaacgca tcactttgcc gataccttcg ttgaggttgc agtacgcccg gttgccgtcg
    17701 gtcacgttct cgaccaccag catcggcata ctggcagaag taatgccgcc cattggcccg
    17761 acggcattca catggtgaca aggaatgaag ttcacttccc cctgctccag tattgccagc
    17821 gcctgcgctt catctttcgc ccagccttcg aacagacatg cgcccacgca cgcccctttc
    17881 atgggtccgg tcatctcctg ccagcgcatt ggcggcccgg cgtgaagcag tgttttgccc
    17941 tcgtttagtt cgctgataag tgaagaagcc ggttgcacat ccagccagtg tggacgagcg
    18001 cgacgaattt gttcgataac cgcagcattg gcttgcgcca ctgatgtaaa catgggaacc
    18061 ccttattgca aacgttctaa taaacgagcc agttttttat tgccgccggc gactggcgac
    18121 cattggtaat gcacaaccgg tttgctggcg ctttgtagct ccagcgcaaa gctgcgtaat
    18181 ccgatgttaa tcacggcgac gttttccagt aatgacggtg tgtgttgctg agtggcaggc
    18241 gaaagcggac gaatcagtgc cgccgccagc aaggtggctt ccggcagcga actcactacc
    18301 gcgatccctg catcttccag cgtggcgatt tgctgcgagc ggcattgcgg gtcacgttca
    18361 gtgcctgtca ccgtggcaat ggcatacagt ggttgattgt ctgaacgcgc ggcacaggct
    18421 ttttgccagg cgcttaccag cgaggcggca ggatcggcgg tcgcaccgaa gccaatcacg
    18481 acatcaagca gcaatacgcg cacttgcggt ttagcgccga gatcggcaat taactgattg
    18541 cgtaaggctg ggtcgatcat cggatgggga cgcccgacgg tgtagaaatc atcgccgagg
    18601 tcaataatct ggtgaccatc ggcgtcgagc atcatgccgt gatgatgggt atcgtcggct
    18661 tccacgccaa ggtgcccggc aagtaatccc gccgcttcgg cagccagcgt accgccggta
    18721 tacaaaccgc aaataaatcc gctgctggca ggcgttatcg cgttacgtcg cgccgtaacg
    18781 cgtgaaagca ggcaagccag gcgtgcggcc tcatccagcg aggaggcaaa ccagacattc
    18841 tcgtcgcagg ccaccgccgg ggtataacct aaaaacagcg ccaccgtcgg tttgccggtt
    18901 gctttcatgg cattaacaat tttcagacgc acagcttcgg caggcggttt tgaaacaaat
    18961 gccagcattt cgcttttctc gtctgcactg agcatttcca gcgccgtcag cgcactgatg
    19021 ccgcccactt cacggctgag gtcgcgcccg ccaaggccaa tcgcgtgagt aattccctcc
    19081 cctgccagcg caatctgtga gcacagctcc tgaatcccgg taccggaagc gccaatgacg
    19141 ccaatgttgc cttccggcat cacgttagca aaagccagcg gcgtgccggc aatcatcgac
    19201 gtaccgcagt ccggccccat caccagcaag cctttttctc gcgcgcgggt tttaagttgg
    19261 atttcatctt ccagcgtgac gttatcggag aacatcatca cgttgaggtt gcgatccagc
    19321 gcctgattcg ccagctccgc cgcatactcg ccagccactg aaatcagcgc cagactggca
    19381 tcggataatt tctgacaggc actgtcccag cgacgcacct gcgtcaagga ctggctgctg
    19441 cctgacccct gcgccagttg ttttagcgcc tcttcaagct gctgcataat cgcctgcgcg
    19501 atccccgcat ccgccgcttc gctacgaatt gccacgcaaa tatcgttcgg cgtggcgtta
    19561 ttaaaatcgt catgccagaa acctgtggta tctaataacg ctttattggc gggcgtaccc
    19621 atcattacgg aaacatcatc aacattttct gattcgctga gttttcgtga aataatcatt
    19681 aaactgaccg aatcctgaaa acaccctttt ttaataaagg cgtggatcat aacaactcct
    19741 taaaaattgc acccatggca attgcacgag cagtgttaat gtggcgatta cggtatcgat
    19801 gacaacgggt aaataaggtg atgaatatca cacagggatt attaacaaaa gaattcaaat
    19861 aaccgccatg ctattacgtg ttatttttta ataagcgtgg ttgttttaaa aaccaggtta
    19921 aaagcgagcg gattatcaaa taaattctaa ctatattttt ttgcctgtct ggatcacata
    19981 atccagatat tttccctgta tgttaattgc agtcatgctt cacaccgtcg ttaaaaagga
    20041 agacagatga aaatcagtcg ggaaacactc caccagctaa ttgagaataa actctgccag
    20101 gctgggttaa aacgtgagca cgctgcaacc gtggctgaag tattggttta cgccgatgcc
    20161 agagggatcc actctcatgg cgcggtgcgc gtggaatact acgcggaacg catttcaaaa
    20221 ggcggcacca accgcgaacc ggagtttcgt cttgaggaaa ccgggccatg ctcggcaatt
    20281 ttacatgccg acaatgccgc cggacaggtc gcggcgaaaa tgggtatgga acatgccatc
    20341 aaaaccgccc agcaaaatgg cgttgcggtg gtcggtatca gccggatggg tcacagcggc
    20401 gcaatctctt attttgtgca gcaggcagcc cgcgccggat tcattggcat ttcgatgtgc
    20461 cagtccgatc caatggtggt gccgtttggc ggcgcggaaa tttactacgg tactaacccc
    20521 ctggcctttg ccgcgccggg agaaggcgac gagatcctta cctttgatat ggcgactacc
    20581 gtacaggcat ggggaaaagt gctcgacgcc cgctcgcgta atatgtctat cccggatacc
    20641 tgggcggtcg ataaaaacgg tgcaccaaca accgatccgt tcgcggtaca tgctctgctc
    20701 cccgccgccg ggccaaaagg gtatggcctg atgatgatga ttgacgtcct ctcaggcgtc
    20761 ttactcggct taccgttcgg gcgacaggtt agttcgatgt atgacgattt acacgcaggg
    20821 cgtaatttgg ggcaattaca tatagttatt aatccgaact ttttctcctc cagcgaatta
    20881 ttccgtcaac atcttagcca gaccatgcgc gaattaaatg ccattacccc cgcgcccggt
    20941 tttaaccaag tttattatcc cggacaggat caggatatta aacaacgcaa agccgccgtc
    21001 gaaggcatcg aaattgttga tgatatttac cagtatttaa tttccgacgc gctttataac
    21061 acgtcatacg aaacgaaaaa tccctttgcg caataattat tgagacagga ctttcttatg
    21121 attacacatt ttcgtcaagc catagaagaa acgctgccct ggctttcctc ttttggcgct
    21181 gacccaacgg gtgggatgac ccgtttactt tattcgccgg aatggctgga aacccagcag
    21241 caatttaaaa aaagaatggc agcaagtggg ctggaaacac gtttcgatga agtagggaat
    21301 ttatacggtc gcctgaatgg taccgaatat ccacaggaag tgattctgag cggttcgcat
    21361 atcgataccg tggttaacgg cggtaacctc gacgggcaat tcggcgcgct ggcggcgtgg
    21421 ctggcaattg actggttgaa aacgcaatac ggcgcgccgc tacgtacggt cgaagtggtg
    21481 gcgatggcag aagaagaagg cagccgcttc ccgtatgtct tctggggcag taaaaatatc
    21541 tttgggctgg cgaatcctga cgacgtgcgg aatatctgtg atgccaaagg aaatagtttt
    21601 gtcgatgcaa tgaaggcttg cggatttact cttccgaacg ccccgctaac tccgcgtcag
    21661 gatattaaag cctttgtcga actgcatatc gaacagggct gtgtgctgga aagtaatggg
    21721 cagtcaattg gcgtggtgaa tgcaattgtc gggcaacgtc gctatacggt gacgctgaac
    21781 ggcgaatcaa accatgcagg caccacgccg atgggttatc gtcgtgatac ggtttacgct
    21841 ttcagtcgca tttgccatca gtcgatcgaa aaagcgaaaa agatgggcga tccgctggtt
    21901 ctgacctttg gcaaagtaga gccgcgcccg aatacggtaa atgtggtgcc gggtaaaacc
    21961 acgttcacca ttgattgtcg tcataccgac gctgccgtgc tgcgtgattt cacccaacag
    22021 ttagaaaacg acatgcgggc gatttgcgat gaaatggaca tttgtattga tatcgattta
    22081 tggatggacg aagaacccgt gccgatgaat aaggacctgg tcgccaccct gacagaattg
    22141 tgtgaaagtg aaaaactgaa ttactgggtg atgcacagtg gtgccgggca cgacgcgcaa
    22201 attttcgcgc ctcgcgtacc aacctgcatg atttttatcc ccagcatcaa cgggatcagc
    22261 cataacccgg cggaacgcac caatattacc gaccttgccg aaggggtcaa aacgttggca
    22321 ctcatgcttt atcaacttgc ctggcagaaa taaggagtca taaatgggat atttaaataa
    22381 cgtcaccggt taccgcgatg atttactggc taaccgtgcg attgttaaac acggtaattt
    22441 cgcactgtta accccggatg gtctggtaaa aaatattatt ccgggctttg aaaattgtga
    22501 cgcgacaatc ctctccacgc caaagctggg tgcctctttt gttgattatc tggtcacact
    22561 gcatcaaaac ggtggcaacc aacagggctt cggtggcgaa ggcattgaaa cgttcctgta
    22621 tgtgatctct ggaaatatca ctgccaaagc cgaaggcaaa acatttgcct taagcgaagg
    22681 tggctatctt tattgcccac caggctcctt aatgacgttt gttaacgccc aggccgaaga
    22741 cagccaaatc tttttatata agcgccgcta tgttccggta gaaggccatg caccgtggct
    22801 ggtttctggc aatgccagcg aactggaacg cattcactat gaaggtatgg atgatgtgat
    22861 cctgctggat tttctgccca aagagttagg ttttgatatg aacatgcata tcctctcttt
    22921 tgcaccaggt gccagccacg gttatatcga aacacatgtt caggaacacg gtgcctatat
    22981 tctttccggt cagggggttt ataacctcga caataactgg atcccggtga aaaaaggcga
    23041 ttacatcttt atgggcgctt attctttaca ggctggttat ggcgtagggc gtggtgaagc
    23101 gttcagctat atttactcga aagattgtaa ccgcgacgtc gagatttaag tcataccact
    23161 cgcctgatta tttttagcta tgttggattt tgccacggtt tataccgtgg ctttttttgt
    23221 agtaaattca ggtaaaaaaa gatgcgatat aaatcgcatc cgctttaaag gtaagggtca
    23281 gtttttaatt ccctgaccta ttttaatggc gcaggcaata tttcgtgcgc tgttgaagag
    23341 attggtttca ccgctggcga gcacttcggc taaaggtgcc agacgtggca aaatgctgaa
    23401 taccgcatca atgccgtact ggtgcaccac ttccacgcca tcacccaata cgccagcaat
    23461 cccaatcacc gggacattaa actgcttcgc caccgacgcc acacccagcg gcgctttacc
    23521 gcctgccgtt tgcgagtcga tgcgcccttc cccggtaatc accagtgctg cgccctgcac
    23581 tgcctgcgca agattgaccg cattcaacac aatctcaata cctggtttaa tatccgcatt
    23641 gagaaatacc gccgccgcaa tacccatacc gcccgcagcg ccgccgcccg ccatctggca
    23701 gacgttgatt tcagtttgct gttgtaaaac acgggcgtaa ttttgcagcc cctgttccag
    23761 ctcttcgacc atttccggcg ttgccccttt ttgcgggcca aacaccgccg ccgcgccgcg
    23821 tgcccctacc agcgggttat caacgtcaca tgctacttca atatggcagt tcgccagacg
    23881 cggatcgcat tcctccatct caatgcttgc cacgcgcgct aaattgccgc cgttagctgc
    23941 cagcacctga ccgtcggcat caaggaaacg cacaccgagc gcctgcgcca tgcccatacc
    24001 accgtcgacc gtcgcactgc cgccaatgcc gagaataata tggcgaatgc cgttatccag
    24061 cgcatgacga attaactccc ccgtaccaaa actggaggcc agcaacggat tacgcttttc
    24121 aggcgcgacc agcatcaggc cacttgctgc cgccatctca atcaccgccg ttttcccgtc
    24181 gccggtaagg ccataaaaag cattcacttt ttcgcccatc ggcccgcaga cttcaagcgt
    24241 cacgatgttg ccgcccgtcg cggcgaccat cgcatccacc gttccttcgc cgccatccgc
    24301 tatcggcaaa cagatatagt tcgcatcggg aaagagggtc gaaaacccgg ctttaattgc
    24361 ctgacaacat ttttctgcac ttaagctctc tttaaaagag tctggcgcaa tgacaatctt
    24421 cattatcaat cctttttcaa caaattattc gatacgttcc cacggaataa ggttatccat
    24481 aagaacagcc agtaaaatcc cgaccaataa gccgttactg agcagaggac gaagcgttaa
    24541 tggaaggtct tgcagataca caggcggtaa tgccattaaa aatatgccga caaataacgg
    24601 caatgcgagt cgataaatat tgcgagcggt aaacgttatt tgctggctaa acaccagcgc
    24661 ggaaaagagt aaaggcagat aagaaaccag catgaccgcg ctactcacgg gtaaagggat
    24721 actgcaaaac agtcgcgtga gtgccggaac cagcgccacc agcaggcaaa taacgctgcc
    24781 ataaataaac gaacgccgcg tgtaatcgcc tgtctgggtt aataaaccaa tggatgaaac
    24841 aaacggtgaa aatggaatta ccgccagcgg tacggttatc agcgtcataa atccggtcgc
    24901 cacaaagctg cgacgataac gcgtatttcc cgcgccctgc tgcggataaa aaacatccgt
    24961 gccccgaatc gcaccgtagg tattgctgat attcaccaga cctgtaatca ccgccgtcag
    25021 aataattccc ggagacaaag cacctccact gccgagcggg aaccactgcc agtgcaactc
    25081 accggagagc gagtgcgaag aaggaaagca aaagtaccac aacaaccagc cggttatggt
    25141 gccgaccagc aggccataac gggcaaaacg ttgcggcagg aagataatca tccccagtac
    25201 caggcacatc accgccaccg agagcgcgaa cggcggtaac tgaattttaa aatttgggtc
    25261 ggctatgcca aacggcagcc cgagcatacc tttgaaaaag atagtggtca gctgcgcgcc
    25321 cagcatcaac ataaacaaga ccatcaccga cggcgtaaat aaccgtgcca ggcgatggcc
    25381 taatccgcta aaaccaatca acatcgtcag cacgccggag agcgcaatcc ccaccgccag
    25441 gctggtagcg atatcgttga tcggtgtccc gcgcgatgct tcgccaaggg tgatagtaag
    25501 gatggttccc caccacaggc cacccggccc ttccataata gcgcgacgat gaccgcagaa
    25561 cgcctgagcg aagcaggcca gtgcggtagc aagaaaagca tattgcgtga gcgtaagcag
    25621 gctactttgc ggcaactgaa aagcagaaag tagcgtagga ggaaccacaa ccgtgttgca
    25681 aaaaataaag aaaaaccact gaaatcctga taacaggctt tcgcggctca ctgcaaaatt
    25741 gaacataaac acaccttaac cggagaatgc ccgccgcaag gacgggcatt gcaggggcca
    25801 gattactgct gatgtttaag gataaattga cctttcggcg caacagggaa gccctgttca
    25861 atgtcgtaaa tcacatcacc acgtaagatg gttttcgtga tacgcgcgcc aatggtacgg
    25921 ccaacatacg ggctgacttt gtggcgatat tccagatcgt cattggtaag aacatagctg
    25981 ctattcggct gaatgaagac gaagtcggca tcttttcctg gggcgatacg gcctttttgc
    26041 tgcagaccga aaatatctgc tgcgttagtc gccattaatt tgccgaacat tggcagagac
    26101 attccgcgtt tctgtaccgc ttcatcgaac atcacgtcca tacagttttg cagaccggca
    26161 ataccgcccc atgcttccat gatgttgccg gctttcattt ccggagggca tggtgagtgg
    26221 tcggaaacca ggcagtcgat ttcaccgtta aacagttttt cccacatgcc tttctggttt
    26281 tccagatcgc ggatcggcgg tgaacacttc gccagagtgc cgatttcttc gaactgatcg
    26341 gtatccagta caaagtaatg cgggcaggat tcacaagtaa cgtcctgacc ttcctgacgt
    26401 gcacgagtca cttcttcaac gccttccggg ctgctgatat ggcaaacgtg cagacggcaa
    26461 ccggcaactt tcgccagata cagcacgcgg cgaatcgctt ccacttcggt aaataccgga
    26521 cgcgaagcca catagtcatg ggcagttacg cgaccttcac gtttcgcttc ttcgcccagc
    26581 ttctgcgcac ctttgaagaa ctgccagtcg tttacatcac ggaagtcgtt gtcgataccg
    26641 cgatcgccac aggtcgcaac gaagcatttg aagccgacaa cgcccacttc atccagctca
    26701 tgcagacggt cgatgttgta agacaccagg ccaccgagtt gtgccgcatc gatagtcagc
    26761 ttgcctttag cggcatcgaa cttcagttca attgaagcgc ggtcaaccgt tgcaggcagc
    26821 tggttgagcg gcatttcgat catggtggtg ataccacctt ttgccgctgc gcgagtaccg
    26881 gtttcataac cttcccagtg gctacgaccc ggttcagaaa tatgggtgtg cgcatcaacc
    26941 atgcccggcg aaaccaccag accagacgca tccataactt cttttgcatc gcccagatcc
    27001 tgaccgatag cagcaatttt cccgccttta acggcgatat ctacaacgcg agcttcgttt
    27061 tctaaaataa cggtgccgtt tttaatgatt aaatcaaaag acataacaaa ctccttgtaa
    27121 aatacagatt ggtttttaac tcaatgttca atatcgggat taattaacct atggtttttt
    27181 gctctcctgt tttttctgct gttgtacgtt tctttaataa ggcgtaggcc gcaaaggcga
    27241 cgatgacgcc gacaaaccat gaaacacgcg ataacggttc cataaaggga ataaacttac
    27301 cgccaagaga taaaataacg gccaccagag ttactgaaaa cgcggtgagg ttaaaaccgt
    27361 tatcgtaata tttataatcg ccaggtgcgg tgtacagttc atcaagatta atttgcccac
    27421 gcatcaccac aaaataatgt gccatcatga caccaattac cggacccagc attccgccga
    27481 tgatatcgag gaacagataa atactgtcct gattttccat taatttccac gggcagatca
    27541 gcaggctgat aatactggca atcagtacgc cgtttttata ggtcagtttt gtcggtgcaa
    27601 tggcagcaat ctgataaccg gccggaataa tattaccggt ggcgttagtg gaaatagtcg
    27661 tcatcagaat aaccagtacc gcaaagaacg aggcaaacag gctgtcccaa cgctgaacaa
    27721 tatccagcac gttccaggtg tcagcgccgt agtgaatact ggctccggca ataatacata
    27781 ccccagcgac cgcaaacaga atataggcca caactaaacc cagcgtttgc cccagcgctt
    27841 gctcacgaaa cgagtgggcg ttttgcgtaa agtcggatgc gctcaccgcc ggtgccgccc
    27901 agaccgcaac taccgcgtta atcaccacca ggaacaagaa tccactgttt tctgctttct
    27961 gaataccgct cggaatgtag tcaaagattg gaccgagccc gaccagcgaa atcgcccaaa
    28021 tcgccatacc gccgaaaacg atatagatgc acgggttaag aatggcagtg aatttattta
    28081 aaactttgcc accgccaaaa cctataccaa cgttgaccag ccagaagagt aagaaagtaa
    28141 ttaagcccgg tagagaaagc cctaacagcg tgaaatcacc accgagagtt aaaaatcccg
    28201 gccagatttt gccaatcaga atcaagcagg ccagtgaccc cgcataacat tgcaggccaa
    28261 accacataat ggcagcaata ccgcctctta ataatccggg aaacagtgcg ccacgtacgc
    28321 cataagaagc acgcaggatc atggcaaacg gtacgccgta tttactgccc gcagcgccgt
    28381 ttaataccat taccgcggca atgaaaaagg cgctgaggat aattgccagc ataatactaa
    28441 aggttgacaa gccgagaata aaaaagccgc cgaccatcac ataattggga acgttatgaa
    28501 ccgaacccat ccataaggta aaatagttaa atgttttcca ggttcgctgg ctttgcgttt
    28561 tcggcaatag atcttcgcta tagccgcgtt gctggaatag ttttctctga tgttccataa
    28621 atccctctta atttcacgta tcgaataacg ttgttttaat ctagctatga ggaacaaata
    28681 aaataaaaat attattttta atgctgaagc aacatctttg gctgctttct ttttttaata
    28741 ttgctggccg attcattttc tgatatcggc catttttatt gcgggtatca ggccagttta
    28801 tggttagcca ttaattccag cgcctgcact aacgcagagt gatccaactg gctgccaccg
    28861 tttgccgcgc aggtattaaa taactcctgg caggtcgcag tgtttggcag gttcagcgct
    28921 agcgctttcg cactttgcag tgccaggttg agatctttct ggtgcagcgc aattttgaaa
    28981 cctggattaa aagtgcgttt aatcatgcgc tcaccgtgaa cttccagaat acgtgaggaa
    29041 gcaaagccgc ccatcagcgc ctggcgcaca cgtaccgggt ccgcaccggc ttttgaagca
    29101 aatagcaggg cttcagaaac cgcttcaata ttgagcgcca caataatctg atttgccact
    29161 ttgcaggttt gaccatcgcc gttaccgccc acgagggtga tatttttacc gagcagttca
    29221 aacagcggtt taacacgttc aaataccgct tcatcaccgc caaccataat cgacaacgtc
    29281 ccttcacgcg caccgatttc accgccggag actggcgcat cgagataatc gccgcccagt
    29341 tcattcacct gacgagcgaa acgcttagtt tcaatcgggg aaatggagct catatcaaca
    29401 atggttttgc ccttcagcga ggctttggta caaccatttt caccgaacag aacttcttca
    29461 acctgtggtg tatctggcac cataataaaa atgatgtccg atgcttccgt tacctggcgc
    29521 gcagtttcaa cactgacggc acccagtgac agtaattcat cagcaaccgg accaatggtt
    29581 gtgacatgca gttgatgacc ggcacgcgcc agattaatgg ccatcggtgt acccataatg
    29641 cctaagccaa taaatcccag tttcataatt aacctctttt aaatttcgct tttcctgaat
    29701 tcagacaaca cgatcccctg ccaacttagc ggcctaaaaa agcattgcct gaacagcgtt
    29761 acgttttaac ggtacggatc catccagcgt aaaccggctt ccgtggtggt tttgggtgta
    29821 tattcacacc caacccaacc gttgtagtca gaattttcga ttaccttaaa gagataatca
    29881 taattaattt ctccggtccc cggttcgccg cgatgcggat tatcagcaat ttgcaggtga
    29941 ccaattttat cggcccactg agtcatggtg ttggttaatt caccttccat ccgctgcatg
    30001 tgataaatgt catactgaat tttcaaattg cagcaaccaa catcatcaat caatttcagc
    30061 gcctgccgag ttccggtgag atggaaacca ggaatatcaa aatggttaat aggttcaatc
    30121 agtaataaaa tatcttcttt catcagcata ttcgcggcat aacgcaggtt ttctacaagc
    30181 gttgcgtgaa tctgttcact gctgaaacca gccggcgttt taccgaccag acagttaatt
    30241 tttttattac ccagcgcacg ggcataacga atcgctgctg ctacgccatc ccgaaactct
    30301 tcttcacggc caggaataca ggcaataccg cgctcccccg ccgcccagtc acctgccggt
    30361 aaattgtgca gcgtatgttc gagtttatta ctcgccagca cctgttttaa ttcttcaatg
    30421 tcgtagtcat aaggaaacat aaattcaacg ccgcgaaaac cacactgcgc agctttctca
    30481 aaacgggcga gaaaatcata ttcaccaaat aacatcgata aattagcaga gaaacgtaac
    30541 attatttatc tcccttattc atagtgcatg aagcaggttt cagtcggtgc atccgctgcg
    30601 ttatcggcga tatcttcaaa ttccatgacg ttatccagtt cgctgcccat cgaaatattg
    30661 gtcacacgct cgagaataac ttccacgact accggtaccc gatattgcgc cattaaggct
    30721 ttcgcctgtt caaaggctgg cgcaatatct tccggtttga agacgcgaat agctttacaa
    30781 cctaaacctt ccgctacttt tacgtggtca acaccgtagc cattcacttc actggagttg
    30841 atattctcga aagcgagttg cacgcagtag tccatatcaa acgcgcgctg cgactggcga
    30901 atcagcccca gataagcgtt attgaccagt acatggatgt acggaatgtt gaactgtgcg
    30961 ccaacggcca attcttcaat caggaactgg aagtcgaagt caccggaaat cgccaccact
    31021 ttgcgctctg gatcagcggc acaaaccccc agcgccgccg gaatggtcca gcccagcggg
    31081 cctgcctgcc cacagttgat ccagtggcgg tctttaaaga catgcagcat ttgcgcagcg
    31141 gcaatttgcg acagaccaat ggtggtgaca tagcaaacat cacgtccaaa agctttgttc
    31201 atctcttcat acacacgctg cggtttaacc ggaacgttgt cgaagtgtgt tttacgcaac
    31261 aaagtacgtt tgcgctgctg gcactcagca acccactctt tacggcatgg cagacgccct
    31321 gctttttgca tttcctgcgc cacttcaacc agcagtgtca gcgccgcttt agcatcagag
    31381 acaatcccca gatccggaca cagcacgcgg ccaatttgcg tcggctcaat atcgatatga
    31441 acgattttgc gcccttcggt gtatttctct accgaaccgg tatgacggtt agcaaaacgg
    31501 ttaccgatac caaacaccat gtcggacgcc agcaacgttg cgttaccgta acgatgcgcg
    31561 gtttgcagac ccaccatccc ggccatcagt tcatgatcgt ccgggataca gccccagccc
    31621 atcagcgttg ggatcaccgg aacgctggtc agttcagcaa actgttgtaa cagtgcagct
    31681 gcgtcagcat taattacccc gcccccggca acaatcaccg gacgtttggc ctggattaac
    31741 atttctacag ctttttcgat ctgcatacgg ctggcagcag gtttgtagac cggcagcggt
    31801 tcgtacatat caggatcaaa ctcgatttcc gcaacctgaa cgtcgaacgg taaatccacc
    31861 agtaccggtc ccggacgacc agaacgcatc aggtgaaatg cctgttgcag cacacgaggc
    31921 accagcgccg cttcacgtac tgtaaccgcc attttgctga ccggtttagc aattgcttca
    31981 atatctacgg cctgaaaatc ttctttatgc agacgggcgc gcggtgcctg gccggtaatg
    32041 cacagaatag gaatggaatc agcagaagcg gaatagagcg cggtgatcat gtccgtgccc
    32101 gcaggaccgg aagtccccag acatacgccg atattccctg ccgttgcgcg ggtataacct
    32161 tccgccatgt gcgaagcacc ttccacatga cgcgccagaa tgtgacgaat accgccgtgc
    32221 ttacgcatcg ctgagtagaa cggattgatt gcagctcccg gaacaccgaa ggcggtggtg
    32281 ataccttctt tctccagcac atacattgcc gcgtcaacgg ctctcatttt tgccatttta
    32341 ttcctacctc tatttattgg aaaatttttc caactttcaa attttgtcaa aaaaacccgc
    32401 tccgcagagc gggatgcgac agacattatg gatgtgcttt cagtcccaac gccgtgctga
    32461 tatcgcgggc ggtgtctctg accagctcac cctgactgac aaaacgatct tctgtcagtc
    32521 ttgatgaagg cccggagatg gagatagcgg caacaacgct accgacatca tcgtaaattg
    32581 ctgaagctat gcaattcaga cctacaacat gctcttcttt atctacggta tagcccagtt
    32641 cacgcgcttg ttccaggtcc ttcagcaagg tgggcatatc cacaagcgta gttggcgtaa
    32701 actgctgcaa accggtttgc agaatgatgc tcatcaactc ctcttccgcc agcggataaa
    32761 gcaacgcctt gcccgcaccg gaagcatgca gcggcagacg actgcccagt ggcgcacaca
    32821 tcctgaccat tgatttacac tctaactgac caattaatac tgcttcattg ccgttacgga
    32881 tcgcgacatt gaccgtttcg ccggaaagta acatcaggcg gcgcataaac ggcccggcga
    32941 cggagaggac atcgcggtta tggatgtacg ccgcaccgac gttaaagaca cctaatccta
    33001 tatgccacca gcctaattga ctgtcctgat agacaaaatc cgctgcttgt aaaaccttca
    33061 gcaagcgaaa ggtcgtggag agcggcaaat ccagattgag agaaatatcg ctaaccgacg
    33121 aacttccccc acttttttcc agatattgca gaatcgcaat tccccgctct aacgcctgtg
    33181 cgcccttctg tgccacaggc tccgcctgtc ctggcctgcc gcgccgtcta acttccgtca
    33241 tacctacgtt aactccgacc tacaagtgag cataaacaat gaacaattag tttatcttat
    33301 gcaagtcggt tgcaggcgtc acgcaaaaca gagttcctgt tcaggaatac tttcaacatc
    33361 acagttgtca ctgccgccgc gatcgatggt cagaaaatcg gtgacgcgct gccaggcgaa
    33421 aagtgggtga tgccagacgt tacgatggta attcactccc tgttcgccgt tggtgataaa
    33481 cgcccgcagc gttgacaggt ctggtttgtc gtcgcctaac gccacgacca ccacaaacac
    33541 ttcacctttc atcgggataa aggcctgagt gcccagcgga tgacgttcga gttcgtaaat
    33601 ggtcagcggc agattcgccg gttgcgcgcg gttaatgctg ataagcgtac ggtcttgctc
    33661 aagaatctca accagcgcca aatcgtggta acgctccacc aggccattgt taatatggaa
    33721 aaaatcccgt tgctgagttt cgattacgtc gccataagca ctaaaggctt cctgacttaa
    33781 cggtaatacc tgaagtttca tctttttgtc cttgtaacat aattccgttc aaccatcgcc
    33841 gaccggtcag cttggtttca ataacaggca atctaaaacc ttaagagaac aacatcaata
    33901 caaaagttgg aatatttttc caaaactaga tttagtccac aaattgaaca gggttatcat
    33961 gtaaaaatac tgataaatca gaggataaga aaatcacgca acttgcggat ttaaaagggg
    34021 atacctgaag atgttcgatc cagaaacctt gcggactttc attgcggttg ctgaaacagg
    34081 aagtttttca aaagcggcag aacgattatg taaaaccacg gcgacgatca gttatcgcat
    34141 taaacttctg gaagagaata ccggagtagc gctgtttttc cgcacgactc gcagcgtgac
    34201 gttgacagcg gctggcgagc atctactttc ccaggccaga gactggctga gctggctgga
    34261 aagtatgcca agcgagctgc aacaggtgaa tgatggcgtg gaacgccagg tgaatattgt
    34321 catcaacaac ctgctctacc acccccaggc cgtcgcccag ttgctggcgt ggctgaatga
    34381 acgttacccc tttacccagt ttcacatctc ccgacaaatc tatatgggcg tctgggattc
    34441 gctattatac gaaggttttt cactggctat cggcgtcacg ggaaccgagg cgctggcaaa
    34501 tacctttagt cttgatccct tcggatcggt gcaatggcgc tttgtcatgg cggcggatca
    34561 tccgctggcg aacgttgaag agccgctaac agaagcgcag ttgcggcgct ttccggcggt
    34621 caatattgaa gacagcgccc gcaccttaac caaacgcgtc gcctggcgat tgcctgggca
    34681 aaaagagatt attgttcctg atatggaaac gaaaatcgcc gcccatcttg cgggcgttgg
    34741 cattggtttt ttgccaaaat cgctttgcca gtcaatgatc gataatcaac aactagttag
    34801 ccgggtaatc ccaacgatgc gccctccttc gccattgagt ctggcatggc gcaaatttgg
    34861 cagcggcaaa gcggtagaag atattgtgac cttgtttacc cagcgcaggc cggaaatcag
    34921 cggattttta gaaattttcg gcaacccacg cagttaaaaa tcaagtttcc ttgcgcgttg
    34981 gcgcgtaaaa tagcgcgcaa gctgatttga ggttcacttt taactatgca agagagacac
    35041 acggaacagg actatcgtgc cctgctgatt gctgatacgc ccattattga tgttcgcgcc
    35101 cctatcgagt ttgagcaagg cgcaatgccc gccgctatca atctgccgtt aatgaataac
    35161 gatgaacgcg ccgccgttgg cacctgctat aaacagcaag gctcagacgc agcgctggcg
    35221 ctggggcata aactggtggc gggtgaaatt cgtcagcagc gcatggacgc ctggcgggca
    35281 gcgtgcctgc aaaatccgca aggtattctc tgctgcgccc gtggcggtca gcgctcacat
    35341 attgtgcaaa gctggttgta tgcagcgggg attgattatc cgctggtgga aggcggttat
    35401 aaggcactgc gccagaccgc gattcaggcg actattgaac tggcacaaaa accgatagtg
    35461 ctgattggcg gttgtactgg cagcggtaaa acgctgttag tgcagcaaca gccgaacggt
    35521 gttgatctgg aagggctggc gcgccatcgc ggttcggcgt ttggtcgcac gttacaacca
    35581 caacttagcc aggcgagttt tgaaaacctg ctggctgccg aaatgctgaa aaccgacgcc
    35641 cgtcaggatt tgcgcctgtg ggtgctggaa gacgaaagcc ggatgatcgg ttcgaatcac
    35701 ctgccggaat gcctgcgcga gcgaatgact caggcggcga ttgcggtggt agaagatccg
    35761 tttgagatcc gtcttgagcg cctgaacgaa gagtatttct tgcgtatgca tcatgatttt
    35821 acccacgctt atggcgacga acagggctgg caggaatatt gcgaatacct gcatcacgga
    35881 ctttcggcga ttaagcgtcg gctggggtta cagcgctata acgaactcgc tgcccagctg
    35941 gatacggcgc tgacaacgca actcaccacc ggcagcaccg acggtcatct ggcctggctg
    36001 gtgccgttac ttaaagaata ttacgaccca atgtatcgct atcagcttga gaaaaaagcg
    36061 gaaaaagttg tctttcgcgg tgagtgggcg gaagtggcgg aatgggttaa ggcgcggtaa
    36121 tgagggacgt atttgtatta gtcgcgactt gatctgacac atggccttga aaggttgaga
    36181 gttaccggtt ttgatatgag tgtcgaatcc ttatccaaaa caagaggtaa ctctcatgct
    36241 tcatactgcc aatcccgtca tcaaacacaa agccggtttg ctcaatctgg ctgaagaact
    36301 cagcaacgta tcaaaagcct gtaaaatcat gggcgtttcg cgtgatacgt tttatcgtta
    36361 ccgcgaactg gtcgctgaag gcggtgtgga tgcgcagatt aatcgtagtc gccgcgctcc
    36421 taaccttaag aaccgtaccg atgaggcaac tgaacaggct gttgttgatt acgccgtcgc
    36481 tttcccgaca catggtcagc accgggccag caacgagctg cgtaaacagg gggtttttat
    36541 ctccgacagt ggtgtccgtt ctgtctggtt actccataac cttgagaatc tcaaaagacg
    36601 atactgaaca aattttatca ggtgacgttc cgtaaaaagt tgtatggagt tctcgatgca
    36661 gtcggcgcga ctatcagtac ccccgctgaa ccctggacta tcgggccgcc gtactggggc
    36721 atgtcaccct ggcgtgccgc tggttttccg ctaatggttt atttcctctt tctttcccgg
    36781 caagaattta ttttaatccg gaaggattat ttattttcag atagggactc acattaaaca
    36841 cgtaacattt taattaatgc atggctgaat atgtattaca caatgtcaga tatcgtaaaa
    36901 gaccagtgca attctatgta aactctctga ctgttcattt tatttgttgt ttcagggtcg
    36961 gaactcaccc tcaataaaca actgaatacg agtagatatt catcgtctga gctatatggc
    37021 tttacacaat agccgacatg tcttttctca gtcaggaatt ttacttttcc tcactacgaa
    37081 gttgacgact tcgatatggg atagactctt aattcaagca attactctgc acaagcatca
    37141 ggcaatccag ctccaatatt tgttataaaa taatgagtaa cattaatttc accaacaaaa
    37201 aaaggtttac accatcccct tgccctggta tcttaccata tttacaccac actttttttg
    37261 tatctggatc attctttgat acgattttcg ccacttgttc cctggccctc actgtcaatg
    37321 ttttcttaaa cctaccccca tcatcatttg ttagggaaaa ataagaaaaa aaataatcat
    37381 cttctacatt tgtgtatatt gatatatcca ccgctacgtg cggaaaaaaa tctgggagcc
    37441 atgtaaaaac tccatcattt tctggtattg ccatatagtt tatgtaatgt ttacttacaa
    37501 gagattcatc tttgtataaa taaagataag taattacgca taaaacaaca atgattataa
    37561 tagcaaaa
//
LOCUS       DAZUDJ010000048        37294 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.048, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000048 DAZUDJ010000000
VERSION     DAZUDJ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37294
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.048"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(96..338)
                     /gene="yiiF"
                     /locus_tag="ACHY1N_003147"
     CDS             complement(96..338)
                     /gene="yiiF"
                     /locus_tag="ACHY1N_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YiiF"
                     /protein_id="HFS4045419.1"
                     /translation="MNSLAGIDMGRILLDLSNEVIKQLDDLEVQRNLPRADLLREAVD
                     QYLINQSQTARTSVPGIWQGCEEDGVEYQRKLREEW"
     gene            complement(557..775)
                     /gene="yiiE"
                     /locus_tag="ACHY1N_003148"
     CDS             complement(557..775)
                     /gene="yiiE"
                     /locus_tag="ACHY1N_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312842.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032993 - protein-DNA complex [Evidence
                     IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HFS4045420.1"
                     /translation="MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQ
                     QFPVRKAKGGRQKGEVVGVDDQCKEHKE"
     gene            complement(1361..1651)
                     /gene="nadS"
                     /locus_tag="ACHY1N_003149"
     CDS             complement(1361..1651)
                     /gene="nadS"
                     /locus_tag="ACHY1N_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NadS family protein"
                     /protein_id="HFS4045421.1"
                     /translation="MDKALFERLTHSMAQMNEIIEGTRQPSRTFEVDAMKIKEIRRAS
                     GLSQSKFADLISVSVDTLRNWEQGRRSPTGPAKALLRAIANDPQHVLQALNR"
     gene            complement(1652..1963)
                     /locus_tag="ACHY1N_003150"
     CDS             complement(1652..1963)
                     /locus_tag="ACHY1N_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFS4045422.1"
                     /translation="MLFIETEIFTEDVQKLLTDDEFSRFQFFLALNPDYGEVIPETGG
                     LRKVRWVSGGKGKRAGVRVIYFHQVKHYEIRLLLIYRKGIKDDLSPQEKAMLRLLNTR
                     W"
     gene            2192..3100
                     /locus_tag="ACHY1N_003151"
     CDS             2192..3100
                     /locus_tag="ACHY1N_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4045423.1"
                     /translation="MALEKGIAELVEKFIAAGRPSSRQQSIAQRREGYIASAVLAGET
                     ETRVDIQTIELEGMTLRIVSPLNAPTLLPTIIYYYGGCFVSGGFATHDNQLRQLAYYG
                     QCRVIAVQYRLAPEHTFPAAHDDAQRGAEIVWQHAERLGVDKQRITLAGDSAGGHLAL
                     VTALRLKRAGEWQPAQLILIYPMLDATAHFESYIRNGHDYIITRDTLLSGFEMYLPGI
                     ERRHPEASPLWRDDFNGLPPVHIITAEYDPLCDEGEALYHRMTGQGVQCTCQRYLGVI
                     HGFFQLGGISEAARSALRDVAWRAGR"
     gene            complement(3164..4105)
                     /gene="fabY"
                     /locus_tag="ACHY1N_003152"
                     /gene_synonym="yiiD"
     CDS             complement(3164..4105)
                     /gene="fabY"
                     /locus_tag="ACHY1N_003152"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HFS4045424.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAH
                     HQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFINQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPHAIADLGALSGDLDRLARGRKARVQM
                     QVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     gene            complement(4150..4587)
                     /gene="dtd"
                     /locus_tag="ACHY1N_003153"
     CDS             complement(4150..4587)
                     /gene="dtd"
                     /locus_tag="ACHY1N_003153"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFS4045425.1"
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANR
                     LCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRA
                     EALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     gene            complement(4584..5456)
                     /gene="yihY"
                     /locus_tag="ACHY1N_003154"
     CDS             complement(4584..5456)
                     /gene="yihY"
                     /locus_tag="ACHY1N_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HFS4045426.1"
                     /translation="MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEDDEP"
     gene            complement(5450..6049)
                     /gene="yihX"
                     /locus_tag="ACHY1N_003155"
     CDS             complement(5450..6049)
                     /gene="yihX"
                     /locus_tag="ACHY1N_003155"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709685.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HFS4045427.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGAWSDLTRIPLASLKKSFHMGEAF
                     HQHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPSD
                     TVFFDDNADNIEGANQLGITSILVKDKTTIPDYFAKVLC"
     gene            complement(6148..6933)
                     /gene="csqR"
                     /locus_tag="ACHY1N_003156"
     CDS             complement(6148..6933)
                     /gene="csqR"
                     /locus_tag="ACHY1N_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418320.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4045428.1"
                     /translation="MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQTEEKKAIAEAVADYIPDGSTIFI
                     TIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPS
                     AASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHA
                     SAAVEIGNVAQVTALFTDELPPAALKSRLQDSQIEIILPQEDA"
     gene            complement(6967..7863)
                     /gene="yihV"
                     /locus_tag="ACHY1N_003157"
     CDS             complement(6967..7863)
                     /gene="yihV"
                     /locus_tag="ACHY1N_003157"
                     /EC_number="2.7.1.184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructose kinase"
                     /protein_id="HFS4045429.1"
                     /translation="MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATA
                     AVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVNTRYTKRYNQAKSSQSAIMVDTK
                     GERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLD
                     GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGC
                     DWLENGGRQHQPAFKVDVVDTTGAGDVFHGALAVALATSGDLAESVRFASGVAALKCT
                     RPGGRAGIPDCDQTRSFLSLFV"
     gene            8031..8927
                     /gene="yihU"
                     /locus_tag="ACHY1N_003158"
     CDS             8031..8927
                     /gene="yihU"
                     /locus_tag="ACHY1N_003158"
                     /EC_number="1.1.1.373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
                     /protein_id="HFS4045430.1"
                     /translation="MAAIAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKG
                     ATPAANPAQAAKDAEFIITMLPNGDLVRNVLFGENGVCEGLSTDALVIDMSTIHPLQT
                     DKLIADMQAKGFSMMDVPVGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELIN
                     SGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTT
                     SWPNKVLSGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYSQARAAGRGR
                     QDWSAILEQVRVSAGMTAKVKM"
     gene            8951..9829
                     /gene="yihT"
                     /locus_tag="ACHY1N_003159"
     CDS             8951..9829
                     /gene="yihT"
                     /locus_tag="ACHY1N_003159"
                     /EC_number="4.1.2.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructosephosphate aldolase"
                     /protein_id="HFS4045431.1"
                     /translation="MNKYTINDITRASGGFAMLAVDQREAMRMMFAAAGAPAPVADSV
                     LTDFKVNAAKALSPYASAILVDQQFCYRQVVEQNAIAKSCAMIVAADEFIPGNGIPVD
                     SVVIDRKINPLQIKQDGGKALKLLVLWRSDEDAQQRLDMVKEFNELCHSHGLVSIIEP
                     VVRPPRRGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGPQQELLCASQRLNDHI
                     NMPWVILSSGVDEKLFPRAVRVAMTAGASGFLAGRAVWASVVGLPDNELMLRDVCAPK
                     LQQLGDIVDEMMAKRR"
     gene            9846..11087
                     /gene="yihS"
                     /locus_tag="ACHY1N_003160"
     CDS             9846..11087
                     /gene="yihS"
                     /locus_tag="ACHY1N_003160"
                     /EC_number="5.3.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418316.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovose isomerase"
                     /protein_id="HFS4045432.1"
                     /translation="MKWFNTLSHNRWLEQETDRIFDFGKNSVVPTGFGWLGNKGQIKE
                     EMGTHLWITARMLHVYSVAAAMGRPGAYSLVDHGIKAMNGALRDKKYGGWYACVNDEG
                     VVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEIIEKYFWSEEEQMCLESWDE
                     AFSKTEEYRGGNANMHAVEAFLIVYDVTHDKKWLDRAIRVASVIIHDVARNNHYRVNE
                     HFDTQWNPLPDYNKDNPAHRFRAFGGTPGHWIEWGRLMLHIHAALEARCEQPPAWLLE
                     DAKGLFNATVRDAWAPDGADGIVYTVDWEGKPVVRERVRWPIVEAMGTAYALYTVTGD
                     RQYETWYQTWWEYCIKYLMDYENGSWWQELDADNKVTTKVWDGKQDIYHLLHCLVIPR
                     IPLAPGMAPAVAAGLLDINAK"
     gene            11225..12127
                     /gene="yihR"
                     /locus_tag="ACHY1N_003161"
     CDS             11225..12127
                     /gene="yihR"
                     /locus_tag="ACHY1N_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709679.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose-1-epimerase"
                     /protein_id="HFS4045433.1"
                     /translation="MQITNMHCSGQTVSLAAGDYHATIVTVGAGLAELTFQGCHLVIP
                     HKPEEMPLAHLGKVLIPWPNRIANGCYRYQGQEYQLPINEHSSKAAIHGLLAWRDWQI
                     SELTATSVTLTAFLPPSYGYPFMLASQVVYSLNAHTGLSVEIASQNIGTVAAPYGVGI
                     HTYLTCNLTSVDEYLFQLPANQVYAVDEHVNPTTLHHVDELDLNFTQAKTIAATKIDH
                     TFKTANDLWEITITHPQQALSVSLCCDQPWVQIYSGEKLQRQGLAVEPMSCPPNAFNS
                     GIDLLLLEPGKPHRLFFNIYGQRK"
     gene            12326..14362
                     /gene="yihQ"
                     /locus_tag="ACHY1N_003162"
     CDS             12326..14362
                     /gene="yihQ"
                     /locus_tag="ACHY1N_003162"
                     /EC_number="3.2.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovosidase"
                     /protein_id="HFS4045434.1"
                     /translation="MDTPRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSG
                     IADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGR
                     LLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
                     TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALW
                     EDKATLRFECADTYISLLEKLTALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMR
                     NAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRIKQWNQEGVQFLAYI
                     NPYVASDKDLCEEAAQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKK
                     NMIELGCGGWMADFGEYLPTDTYLHNGISAEIMHNAWPALWAKCNYEALEETGKLGEI
                     LFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGY
                     TTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFARMTSVFT
                     TLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDILIAPVHEEGRS
                     DWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI"
     gene            14408..15793
                     /gene="yihP"
                     /locus_tag="ACHY1N_003163"
     CDS             14408..15793
                     /gene="yihP"
                     /locus_tag="ACHY1N_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4045435.1"
                     /translation="MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFY
                     TDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTL
                     LAIANFVGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
                     RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYV
                     ETQPTNPAQKPGLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDP
                     ILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVSF
                     VAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGF
                     FPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRI
                     VEEIEARKRTA"
     gene            15836..17239
                     /gene="yihO"
                     /locus_tag="ACHY1N_003164"
     CDS             15836..17239
                     /gene="yihO"
                     /locus_tag="ACHY1N_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4045436.1"
                     /translation="MSDHNPLTLKLNLREKIAYGMGDVGSNLMLCIGTLYLLKFYTDE
                     LGMPAYYGGIIFLVAKFFTAFTDMLTGFLLDSRKNIGPKGKFRPFILYAAVPAALIAT
                     LQFIATTFCLPVKTTIATALFMMFGLSYSLMNCSYGAMIPAITKNPNERAQLAAYRQG
                     GATIGLLICTVAFIPLQSLFSDSTVGYACAALMFSIGGFIFMMLCYRGVKEHYVDTAP
                     TGHKASILKSFCAIFRNPPLLVLCIANLCTLAAFNIKLAIQVYYTQYVLNDINLLSWM
                     GFFSMGCILVGVLLVPVTVKCFGKKQVYLAGMVLWAVGDILNYFWGSNSFTFVMFSCV
                     AFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFFRKISAALAGFLPGIML
                     TQIGYVPNIAQSDATLQGLRQLIFIWPCALAIIAALTMGFFYTLNEKRFALIIEEINQ
                     RKNKEMATEEKTASVTL"
     gene            17307..17999
                     /gene="ompL"
                     /locus_tag="ACHY1N_003165"
     CDS             17307..17999
                     /gene="ompL"
                     /locus_tag="ACHY1N_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpL"
                     /protein_id="HFS4045437.1"
                     /translation="MKKINAIILLSSLTSASVFAGAYVENREAYNLASDQGEVMLRVG
                     YNFDMGAGIMLTNTYTFQREDELKHGYNEIEGWYPLFKPTDKLTIQPGGLINDKSIGS
                     GGAVYLDVNYKFVPWFNLTVRNRYNHNNYSSTDLSGELDNNDTYEIGTYWNFKITDKF
                     SYTFEPHYFIRVNDFNSSNGKDHHWEITNTFRYRINEHWLPYFELRWLDRNVEPYHRE
                     QNQIRIGTKYFF"
     gene            complement(18090..19355)
                     /gene="yihN"
                     /locus_tag="ACHY1N_003166"
     CDS             complement(18090..19355)
                     /gene="yihN"
                     /locus_tag="ACHY1N_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4045438.1"
                     /translation="MLTKKKWALFSLLTLCGGTIYKLPSLKDAFYIPMQEYFHLTNGQ
                     IGNAMSVNSFVTTVGFFLSIYFADKLPRRYTMSFSLIATGLLGVYLTTMPGYWGILFV
                     WALFGVTCDMMNWPVLLKSVSRLGNSEQQGRLFGFFETGRGIVDTVVAFSALAVFTWF
                     GSGLLGFKAGIWFYSLIVIAVGIIIFFVLNDKEEAPSVEVKKEDGASKNTSMTSVLKD
                     KTIWLIAFNVFFVYAVYCGLTFFIPFLKNIYLLPVALVGAYGIINQYCLKMIGGPIGG
                     MISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAV
                     FFAPIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDLNPGIIGYKIVFGIMA
                     CFAFCGAVVSVMLVKRISQRKKEMLAAEA"
     gene            complement(19457..20437)
                     /gene="yihM"
                     /locus_tag="ACHY1N_003167"
     CDS             complement(19457..20437)
                     /gene="yihM"
                     /locus_tag="ACHY1N_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HFS4045439.1"
                     /translation="MVTINNARKILQRVDTLPLYLHAYAFHLNMRLERVLPADLLDIA
                     SENNLRGVKIHVLDGERFSLGNMDDKELSAFGDKARRLNLDIHIETSASDKASIDEAV
                     AIALKTGASSVRFYPRYEGNLRDVLSIIANDIAYVRETYQDSGLTFTIEQHEDLKSHE
                     LVSLVKESEMESLSLLFDFANMINANEHPIDALKTMAPHITQVHIKDALIVKEPGGLG
                     HKACISGQGDMPFKALLTHLICLGDDEPQVTAYGLEEEVDYYAPAFRFEDEDDNPWIP
                     YRQMSETPLPENHLLDARLRKEKEDAINQINHVRNVLQQIKQEANHLLNH"
     gene            complement(20445..21155)
                     /gene="yihL"
                     /locus_tag="ACHY1N_003168"
     CDS             complement(20445..21155)
                     /gene="yihL"
                     /locus_tag="ACHY1N_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4045440.1"
                     /translation="MTGNQSTVENAKEKLDRWLKDGITTPGGKLPSERELGELLGIKR
                     MTLRQALLNLEAESKIFRKDRKGWFVTQPRFNYSPELSASFQRAAIEQGREPSWGFTE
                     KNRTSDIPETLAPLIAVTPSTELYRITGWGALEGHKVFYHETYINPEVAPGFIEQLEN
                     HSFSAVWEKCYQKETVVKKLIFKPVRMPGDISKYLGGSAGMPAILIEKHRADQQGNIV
                     QIDIEYWRFEAVDLIINL"
     gene            complement(21372..23195)
                     /gene="typA"
                     /locus_tag="ACHY1N_003169"
     CDS             complement(21372..23195)
                     /gene="typA"
                     /locus_tag="ACHY1N_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HFS4045441.1"
                     /translation="MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAI
                     TGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDVRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPPIRMTLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD"
     gene            23568..24977
                     /gene="glnA"
                     /locus_tag="ACHY1N_003170"
     CDS             23568..24977
                     /gene="glnA"
                     /locus_tag="ACHY1N_003170"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HFS4045442.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
                     SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLS
                     KNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            25151..26200
                     /gene="glnL"
                     /locus_tag="ACHY1N_003171"
     CDS             25151..26200
                     /gene="glnL"
                     /locus_tag="ACHY1N_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HFS4045443.1"
                     /translation="MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNEVTLVIDGRSHILSVTAQRMPDG
                     MILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRVTESIHKVAERVVTLVSMELPDNV
                     RLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            26212..27621
                     /gene="glnG"
                     /locus_tag="ACHY1N_003172"
     CDS             26212..27621
                     /gene="glnG"
                     /locus_tag="ACHY1N_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HFS4045444.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNIQLNGPTTDIIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELG
                     VEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESTVAE
                     STSQMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAR
                     LLGWGRNTLTRKLKELGME"
     gene            27733..27843
                     /gene="yshB"
                     /locus_tag="ACHY1N_003173"
     CDS             27733..27843
                     /gene="yshB"
                     /locus_tag="ACHY1N_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HFS4045445.1"
                     /translation="MLESIINLVSSGAVDSHTPQTAVAAVLCAAMIGLFS"
     gene            complement(28033..29406)
                     /gene="hemN"
                     /locus_tag="ACHY1N_003174"
     CDS             complement(28033..29406)
                     /gene="hemN"
                     /locus_tag="ACHY1N_003174"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004109 - coproporphyrinogen oxidase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HFS4045446.1"
                     /translation="MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAG
                     RHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAF
                     LTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     CYAQNQKELKQYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEKQW
                     DLHFADYFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARM
                     QQFSRVI"
     gene            complement(29595..30104)
                     /gene="yihI"
                     /locus_tag="ACHY1N_003175"
     CDS             complement(29595..30104)
                     /gene="yihI"
                     /locus_tag="ACHY1N_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HFS4045447.1"
                     /translation="MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGS
                     RAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELL
                     ETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQE
                     DMMRLLRGN"
     gene            complement(30223..30389)
                     /locus_tag="ACHY1N_003176"
                     /pseudo
     CDS             complement(30223..30389)
                     /locus_tag="ACHY1N_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546704.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            30686..31318
                     /gene="yihA"
                     /locus_tag="ACHY1N_003177"
     CDS             30686..31318
                     /gene="yihA"
                     /locus_tag="ACHY1N_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFS4045448.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE"
     gene            complement(31700..34486)
                     /gene="polA"
                     /locus_tag="ACHY1N_003178"
     CDS             complement(31700..34486)
                     /gene="polA"
                     /locus_tag="ACHY1N_003178"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFS4045449.1"
                     /translation="MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
                     GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEVTATVISYDNYVTIL
                     DEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDA
                     PDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAEL
                     EKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPL
                     LVEVGSGENWDQAH"
     gene            34850..35782
                     /gene="yihG"
                     /locus_tag="ACHY1N_003179"
     CDS             34850..35782
                     /gene="yihG"
                     /locus_tag="ACHY1N_003179"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HFS4045450.1"
                     /translation="MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVK
                     LLLPVPVIWRKVSRFCDFMMYCWCEGLAVLLHLNPHLQWEVHGLEGLSKKNWYLLICN
                     HRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWSLDMPFMKRYSRAYLLRH
                     PERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIA
                     MALNVLGKQFDKLLNVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYIN
                     DKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQNK"
     gene            complement(35823..37253)
                     /gene="yihF"
                     /locus_tag="ACHY1N_003180"
     CDS             complement(35823..37253)
                     /gene="yihF"
                     /locus_tag="ACHY1N_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418298.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HFS4045451.1"
                     /translation="MIRKSATGVIVALAVIWGGGTWYTGTQIQPGVEKFIKDFNDAKK
                     KGEHAYDMTLSYQNFDKGFFNSRFQMQMTFDNGAPDLNIKPGQKVVFDVDVEHGPLPI
                     TMLMHGNVIPALAAAKVNLVNNELTQPLFIAAKNKSPVEATLRFAFGGSFSTTLEVAP
                     AEYGKFSFGEGQFTFNGDGSSLSNLDIEGKVEDIVLQLSPMNKVTAKSFTIDSLARLE
                     EKKFPVGESESKFNQINIINHGEDVAQIDAFVAKTMLDRVKDKDYINVNLTYELDKLT
                     KGNQQLGSGEWSLIAESIDPSAVRQFIIQYNIAMQKQLAVHPELANDEVALQEVNAAL
                     FKEYLPLLQKSEPTIKQPVRWKNALGELNANLDISIADPAKSSSSTNKDIKSLNFDVK
                     LPLNVVTETAKQLNLSEGMDAEKAQKQADKQISGMMTLGQMFQLITIDNNTASLQLRY
                     TPGKVVFNGQEMSEEEFMSRAGRFVH"
BASE COUNT         9158 a         9511 c         8996 g         9629 t
ORIGIN      
        1 tgcatgactt tgtaggcctg ataaggcgct cacgccgcat ccggcatgaa caacgcgcac
       61 gttgtcagca atctgattga catcattttt tcccattacc attcctcgcg cagcttacgc
      121 tgatattcga caccatcttc ctcacaccct tgccagatgc caggaacact ggttcttgct
      181 gtttgcgatt gatttatcag gtattgatct accgcttccc ttaataggtc cgcacgagga
      241 agattacgct gcacctcgag atcatcaagt tgcttaatca cctcattcga taaatcgagt
      301 aaaattctgc ccatatctat acctgccaga gagttcataa atatctcgcc aatatcattt
      361 ttgaatctat ggagagaaaa gtacccttgc cgaatcttta aagaaagctc atttacgcat
      421 cattttttat ttttgcgagg cgttttccag atacgatgta acagttgcag ttattataag
      481 ttcaagtaaa acagccttgt attaatacca gaataagggc atctgttttt ttatattcaa
      541 gaatgaaaaa tttttttcat tccttatgct ccttacactg atcatcaaca ccaactacct
      601 cccccttttg cctgcctccc tttgctttac gcaccggaaa ttgctgccgc tccagatatt
      661 gctcaaccgc ttcgcgtaaa attgcagatc gtgaaacctt acgccagccc cgaagtttgt
      721 tcagccgttt aattgcctct tctgataaat gaagaaaaac cgtattcatc gccattacca
      781 ccaccttacc tatattactc attaatgtat gtgcgaaaat tacgccggaa aatcatttaa
      841 aaaaagcgga tttttgcatg ttgttttgtt tttgcgaggc gttttccaga aataataaga
      901 gtgttgcagt tgtttcattt attactcaaa aatggtttag ttatcgccca ggatgaatta
      961 tgggtgctat gaatatatta tattcagaga tatttatttg cataatctga atggtgtagc
     1021 cgaaaaacgt cagcatccta acagcaccag gatttaaggt gaaattaatc atccatcaca
     1081 gaccggtcag tactgccacc aaccggtctt tacttgttca tcgttataat tttgttggta
     1141 acagttcggg aaacaaggaa ttccttccgg aaccccccgg tatcatccga tagcattgac
     1201 gtcaatcatc agcgcgacga tgagtttttt taatcgcatc atagggtggc gacgttcagc
     1261 acgattacgg gtcatagcaa aactcctggg caggcgacca ctatgccgct ttcacaggag
     1321 ttctgaatgc tagtgctttc tgtatggcat aaccatgcct ctaacggtta agtgcttgca
     1381 gcacatgttg cggatcattg gcaatcgctc gcagcaaagc ctttgcaggc ccggtcggtg
     1441 aacgtcgccc ctgctcccag ttacgcaacg tgtctacgct tacagaaata agatcggcaa
     1501 atttagattg tgacaaccct gaagcgcggc gtatttcttt gattttcata gcatcaactt
     1561 caaaagtccg cgaaggctgt cgcgttcctt caataatttc attcatctgg gccatgctgt
     1621 gagtcaaccg ctcaaaaagt gccttatcca tttaccacct cgtatttaac aaccggagca
     1681 ttgctttttc ctggggagac agatcatctt taataccctt acgataaata agcagtaatc
     1741 tgatctcata atgtttaacc tgatgaaagt aaataaccct gacaccagca cgtttcccct
     1801 ttcctcctga aacccatcga acctttctta acccaccagt ttcaggtatt acctcaccat
     1861 agtcaggatt caaggccagg aaaaactgaa aacgactgaa ttcatcgtcg gtcagcagtt
     1921 tttgaacatc ttcagtaaaa atttccgttt cgatgaagag cataattata cgccattggc
     1981 ttagagtaac aatccttttt gtacgtcatt gacgtaccct tgaaaccact agcttactga
     2041 tagtgctcca gcaaaaccac gtctctgccg ggtttgtctt tagatttgcg aggcgctttc
     2101 cagatttttc acgcccgtga atttccctgt atccatccag caaaaacggg tgtataagac
     2161 tgtacattca tacagcaaaa taagttctac tatggcactg gaaaaaggaa ttgcagagtt
     2221 agtcgaaaag tttatcgctg cgggtcgccc ctcatcgcgt caacaaagta ttgcgcagcg
     2281 cagggagggc tatatcgcca gcgctgtcct tgcgggtgag acagaaacgc gggtagatat
     2341 tcagactatc gaacttgaag ggatgacctt acgaatagtg tcgccgctga atgccccgac
     2401 attactcccg acgataattt attactacgg tggctgtttt gttagcggcg ggttcgcaac
     2461 tcacgacaac cagctgcgcc agttagccta ttacgggcaa tgtcgggtta ttgccgtcca
     2521 gtatcggctg gcaccggaac atactttccc cgccgcccat gatgatgcgc aacgaggtgc
     2581 agaaatagtc tggcaacacg ccgaacgact cggcgttgat aaacaacgta taactcttgc
     2641 cggtgacagt gcgggcggac atctggcgct ggtaactgct ttgcgattaa agcgtgctgg
     2701 cgagtggcaa ccggcacaac tcatcttaat ttatcctatg cttgatgcga ctgcgcattt
     2761 cgaaagctac atacgcaatg gtcacgatta catcatcaca cgcgacactt tactgagcgg
     2821 ctttgagatg tatctgccag gcattgaacg caggcatcct gaagccagcc ctctttggcg
     2881 cgatgatttc aatggcttgc cacctgtaca tatcattacc gctgaatacg acccactttg
     2941 cgatgaaggt gaagcgttgt atcaccgcat gacagggcaa ggagtgcaat gcacctgcca
     3001 acgctacctt ggcgttatcc acggattttt tcagttaggt ggtatcagcg aggccgcgcg
     3061 atcggcacta cgggatgttg cctggagagc gggaaggtaa cttcggacct gggccctgaa
     3121 aaggttttca gattgaaaac cttttcagtc aagtaaaacg cccctactct tcttcgttcc
     3181 cgccctcttc atacgggcca aatggcttcg cgggcagaac gatatacgtg ccttcaaaca
     3241 ctgcacccgg cgtctcgtcg ccaaagattt caacttgcat ctgcacccgt gcttttcgtc
     3301 cgcgcgccag acggtcgaga tcgccgctta aggcaccaag gtcggctatc gcatgaggtt
     3361 taccgctaat cggcttgctg tagcggatat gcgcatccgc cagaataatc gttccgccga
     3421 gatggcgttc gcgcagcatc agccagataa gcccccaacc ggtgagcgtc gccagcgaga
     3481 ataaactccc ggcaaacagc gtatggtgcg gattctgatt gccggtttcc ggcatggtgg
     3541 tgataaattt ttgcccggta tattgttgaa tgcgcacgcc cattttttcg cttaatggaa
     3601 tgtgttcata ccacgcctgt tgcagctggg cgcaccagtc accgcgatgc agaatatcat
     3661 ccagagtggc aacgggttta atcatcaaaa aatggcgaat cggcgtggta gttggggtgg
     3721 tgatctcccc ctgattaatg aatcccagct tggcgaaaaa ctccaccgcg tcttcacggg
     3781 cgctacaggt cacgcgctta acgccttcct gacgcgccac cgactccagg gtcatcgcca
     3841 tcagcgttcc taaccctttg tcctgcacgt cgggatgaac ggccataaag cgaatggacg
     3901 cttcattgtc ggcattaata tacaatcggc ctaccgccac cagattaccc tgctcgtcga
     3961 cgaccatctg gtgatgcgcc atcgcatccc acgcgtcgcg ttccgaacct tttggttgat
     4021 gcaggggctt acgcaacatt tcccagcgaa actgatagta acgctctaat tcttcttctg
     4081 tttgtggaac ccgaaggtga tacatagcga tactctctct tgtttcccgt gacaaccctg
     4141 gaagctggct catacctgca accagaatgt cacggggcca tcattgacca gcgatacctg
     4201 catatcggca gcgaagcgtc ctgtttgcgt gttcatctct tgctggcggc agcgttcgac
     4261 gaaatagtca tataacgcct ctgcgcgatc cggtgatgcg cctttggaga aacttgggcg
     4321 catccctcgt tcggtatctg cggcgagggt aaactgggaa accaccagta cactgccgcc
     4381 cgcctgttgc acgttgagat tcatcttgcc ttcggcatcg ctaaagatgc ggtagccgag
     4441 cacacgctcg cacagacggt ttgctttctg ttcgtcgtca tccttttcga cacccaataa
     4501 caccaaaagt cccgcgccaa tttcgcccgt cacttctccc tccacggtga cgctggcacg
     4561 ggttacgcgt tgaattaatg caatcatggt tcgtcgtctt cttcttgttc agctgcttgt
     4621 tttagtttgc ggtattcccc gagagtgaca gtaatttccg cgccaagcaa gacgatacac
     4681 catgtccagt agacccaaac aaagagaatg gggatcaccg ccagcacgcc gtaaatgagc
     4741 tgatatgacg ggaacatggt gatataaagc gcgaaacctt tctttcctgc ttcgaacagg
     4801 agtgcagcga caaacgcgcc gacaatcgcg tcgcggttag gtacgcggat ggtaggaaca
     4861 atgctgtaca gcaaccagaa ggagatccac gacaacagca gcggaaaaat acgcagcacg
     4921 ttgtcgatga cagtattgag atcgctcgcc cagcgcaggg agagcaaata ggaactgatc
     4981 gccagactgg cccctgccag cagcggcccc agcgttaaaa tcatccagta cacggcaaac
     5041 gagtaaattt ttggtcgcgc tcgtttactg cgccagatgg tattcaacgc gctatcgatg
     5101 gagtacatca acaataatgc ggtgacgatc agcccgcacg cgccaacggc ggtcatcttg
     5161 ttggaattgg caacaaattg ttcgatatac cgctgaataa catcgccagt agcaggcaga
     5221 aagttggcaa aaataaagtg acgcaactga atgctgacgt cggaaaacat gggaaaagcg
     5281 gcgaaaagcg caaaaacaac ggcaaccagc ggcactaatg agagcaaaga cacataggca
     5341 aggttacctg ccagggttgt catgttgtcc tcatcaatac gttgccagag tagttttagc
     5401 caggcccata gtggacgagt acggtgcctg gctttgtcct gaatggtttt tagcataaca
     5461 ccttcgcgaa atagtccggg atggtggttt tatctttcac cagaatactg gtaatgccca
     5521 gctgattggc tccttctata ttatcggcgt tatcgtcgaa aaagaccgta tcgctgggtg
     5581 aaaaaccttc cgcctgcaaa acatgctggt aaattcgtgc ttcaggtttg cgcatcccca
     5641 gatcttgcga cagatagata tggtcagcag catcacgaat ttccgggtat tcttccggcc
     5701 agaaggtggt atgcaggcgg ttggtattgg aaagcaccac cacgcgatgc ccctgctcac
     5761 gcagtttatg catgatggcg atcacttccg ggcgcagcgc aacaaacacc gcctgccagc
     5821 cgtgagagaa ctgctcgtag cttagcggta gagccatctc atgacacagc gcctctgcga
     5881 acgcttcgtc gctaatttcc ccacgctcat gctgatgaaa cgcctccccc atatgaaaac
     5941 tcttcttaag cgatgccagc ggaatacgcg ttaaatcgct ccaggctccc agcacacggt
     6001 taaagtcgat atcgacaatc acattaccta aatcaaagat atagagcatt tttgcctcct
     6061 ttcgcgccac aagaaattaa ctgtagcggg aaaggatggg tttggctatg tggcaaggta
     6121 tgaagccagg ttaacggtca caaaaatcta cgcgtcttcc tggggaagaa tgatttcaat
     6181 ttggctgtct tgtaagcgtg attttagcgc agcgggcggc agctcgtcgg taaagagcgc
     6241 agtgacctgt gccacgttac caatttcaac cgccgccgaa gcatgatact tagtgtgatc
     6301 ggcgaccagc agaatatttc tcgcgtgcgc catcatcgtt ttcaccacgt tagcttcgtt
     6361 tacatcaaac tccatcaacg cgccatcgct ctcaatcgcc ccaacgcttg ttaccagata
     6421 atcagcacga aaatcagcca caaaggacgc cgctgaaggg ccaatgatcc cgctattatg
     6481 agagcgcaac gtaccgccgg gcaccatcac ttcaaagcgc gggttgtggt aaagaatatg
     6541 cgccacacgc aggctgttgg tgattatccg caaatgatta tggttaagta acgcccgggc
     6601 aacatgctca acagtcgtac caatggtgat aaatattgtt gaaccatcag gaatatagtc
     6661 tgccaccgct tcggcaatcg cttttttttc ctcggtttgc gaaacctcac gctgctcgaa
     6721 cgccgtatta acgacgctgg aagcccgacc cgcgccaccg tgatggcgcg taatcaggcc
     6781 ttgctcgctt aatttacgaa tatcccggcg gaccgtctgc gtggagacat ccagcagatt
     6841 tgccagctca tcaatattca tatacccacg ctcggcgatc agcatgagga gttggtcgtg
     6901 ccgcgggtta ccggttagtt cggtaaggct catgaaaatt cctcgaaaaa ccatcaccct
     6961 ggcattttat acaaaaagtg acaaaaaaga tcgggtttga tcacagtcag ggatcccggc
     7021 tcgtccaccg ggacgtgtgc attttaacgc cgctacaccg ctggcgaagc ggactgactc
     7081 cgctaaatcc ccacttgttg ccagcgccac cgccaaagcg ccgtgaaaaa catcacccgc
     7141 acctgtggta tctaccacat caactttgaa ggccggttga tgctgacgcc caccattttc
     7201 cagccagtcg cagcctgcgc taccctgggt cacatagaca tgaccatttg tgagcgtttg
     7261 tgcctgtttt agcgcactgg ccatctcttt cacgcccgtt aagcgcgcca gacccggttc
     7321 tgaaaaggcc gcgtgatcgc ttaatgccac cagctcactg atatcctgcg gcgtaatgtc
     7381 cccgtccaga acggtcatca cacccgcctg acgggccagg gtgaaggctt ttttagcgcc
     7441 gtcgtgccag cgtacatctg ccagcacaac atcccactga gagaaatcaa tttcctccaa
     7501 ccactctgcg tcaggcagca gatccgggct ggggtagtta atgattatcc gctcgccttt
     7561 ggtatccacc atgatggcgg attgcgaaga tttcgcctgg ttataccgtt tggtgtaacg
     7621 ggtgttaacg ccccaggatt ccagctctgc cagcaggctg ttgcccgtgt cgtcatcacc
     7681 tacgcgacca ataaaatcga cctgcgcccc cagccttgcc gccgcaaccg ctgccgtcgc
     7741 cgctggcccg ccaccaactt ccgtataatt tctcgccacg tatttaccgc tctccgtcgg
     7801 taacccttcc acgtaataga tgcgatccat cacggttata cctacacaag caacacgaat
     7861 catggtcatt ccttaaacat tttgggatgc gttcatttta atttcaccaa ttgtttaaaa
     7921 agtgacggct gtcaattttt tgacgataaa ttacaaatac gatcaaaaac agacaagcaa
     7981 agcatgtcat aaatgacaaa aagtgacatc actgtattca ggagagggtt atggcagcaa
     8041 tcgcgtttat cggtttagga caaatgggtt cgccaatggc gagcaattta ttgcagcaag
     8101 ggcatcaact tcgcgtcttt gatgtgaacg ccgaagctgt gcggcatctg gtagacaaag
     8161 gtgcgactcc cgccgccaac ccggcgcagg ccgctaaaga tgccgaattt atcattacca
     8221 tgttgccgaa tggcgatctg gtgcgcaacg tgttgttcgg tgaaaacggc gtttgcgaag
     8281 gcttatctac cgatgcgctg gtcattgata tgtccaccat ccatccgctg caaaccgata
     8341 aattgattgc cgatatgcaa gccaaaggct tcagcatgat ggatgttccg gtaggccgta
     8401 cttctgcaaa tgccattacc ggtactctgt tactgctggc tggcggcacc gctgaacaag
     8461 ttgaacgtgc cacaccgatc ctgatggcga tgggcagtga gttgatcaac tctggcggtc
     8521 cgggcatggg gatccgcgtt aagctcatca acaactacat gagcatcgcg ctcaatgcgc
     8581 tttcggcaga agccgccgtt ttgtgcgaag ccctgaatct tcccttcgat gttgccgtca
     8641 aagtgatgag cggtaccgcc gccggtaaag gtcacttcac cacttcctgg ccaaacaaag
     8701 tcctcagcgg agatctttct cccgccttca tgatcgatct tgcccataag gatcttggca
     8761 tcgcccttga tgtcgccaac cagctgcatg tgccaatgcc gctgggggcc gcctcacggg
     8821 aggtttatag ccaggcgcgc gcagcgggtc gcggtcgcca ggactggtcc gccattctgg
     8881 aacaggtccg tgtcagtgcc gggatgactg ccaaagtaaa aatgtaacga ctggataaag
     8941 gaataaatga atgaataagt acaccatcaa cgacattacg cgcgcatcgg gcggttttgc
     9001 catgctggcg gtcgatcagc gcgaagccat gcgcatgatg tttgccgcgg ctggggcacc
     9061 cgctccggta gccgatagcg ttttaactga tttcaaagtt aacgctgcaa aggccctctc
     9121 gccttatgcc tcggcgattc tggtagatca acaattctgc taccgccagg tggttgagca
     9181 aaacgcgatt gccaaaagtt gcgccatgat tgtcgccgcc gatgagttca ttcctggcaa
     9241 cggtattccg gtcgatagcg tggttattga ccgcaaaatc aatccgctac agatcaaaca
     9301 agacggtggc aaagccttaa aactgctggt gctgtggcgt agtgatgaag atgcgcagca
     9361 acgtctggat atggtgaaag agttcaacga actgtgccac tcacacggtc tggtaagcat
     9421 cattgagcca gtcgtccgcc caccgcgtcg tggcgataaa ttcgatcgcg aacaagcgat
     9481 catcgatgcc gccaaagagc tgggcgacag tggcgctgac ctctacaaag ttgaaatgcc
     9541 gctttatggc aaaggtccgc aacaagagct tctctgtgct tcacaacgtc tgaatgacca
     9601 tatcaatatg ccatgggtga tcctctcttc cggtgtcgac gaaaaactgt tcccgcgtgc
     9661 cgtacgcgtg gcaatgacgg cgggcgcatc gggattcctg gcaggccgtg cagtctgggc
     9721 atcggtcgtc ggtttaccag acaacgagct gatgctgcgt gacgtttgcg caccgaaatt
     9781 acaacaactt ggcgatatcg tcgacgaaat gatggctaaa cgccgctaag atgaggataa
     9841 aaggaatgaa atggtttaac accctaagcc acaaccgttg gctggaacag gaaaccgacc
     9901 gcatctttga ttttggtaaa aattccgtag tgccgactgg ttttggctgg ttaggcaata
     9961 aagggcaaat caaagaagag atgggcaccc atctgtggat caccgctcgt atgttgcacg
    10021 tttattccgt tgctgcggcg atgggtcgac ctggcgctta ctcgttggtt gatcacggta
    10081 tcaaagccat gaacggcgca ctgcgtgata aaaaatatgg cggctggtat gcctgcgtga
    10141 atgacgaggg cgtggtggat gcctccaaac agggctatca acacttcttt gctctgctgg
    10201 gtgccgccag cgccgtcaca acgggtcacc cggaagcgcg caagctgctc gattacacca
    10261 ttgaaattat cgagaaatat ttctggagcg aagaagagca gatgtgcctg gaatcctggg
    10321 acgaagcctt cagcaaaacc gaagagtacc gcggcggcaa tgccaatatg cacgcggtgg
    10381 aagctttctt gattgtttat gacgtcactc acgacaaaaa atggctggat cgcgcgattc
    10441 gcgtggcttc cgtgattatc cacgacgtcg ccagaaataa tcattatcgc gttaacgaac
    10501 acttcgatac ccagtggaat ccgctgccgg attacaacaa agataacccg gcgcatcgct
    10561 tccgcgcgtt tggaggtaca ccaggccact ggatcgaatg gggccgttta atgctgcaca
    10621 tccatgctgc cctggaagcc cgttgcgaac aaccaccagc atggctgcta gaagatgcca
    10681 aaggtctgtt taacgccacc gtgcgcgatg cctgggcacc cgatggcgcg gacgggattg
    10741 tttataccgt tgactgggaa ggaaaaccgg tggtccgcga acgtgtacgt tggcctatcg
    10801 tcgaagcaat gggtacggcc tacgcgctct acaccgtcac tggcgatcgc cagtatgaaa
    10861 cctggtatca aacatggtgg gagtactgca ttaagtacct gatggactat gaaaatggtt
    10921 cctggtggca ggagctggat gcggacaata aggtcaccac caaagtctgg gacggcaaac
    10981 aggatattta tcacctgctg cattgcctgg tgatcccgcg tatcccgtta gcgcccggca
    11041 tggctccagc ggttgcagcg ggtctgctgg atattaatgc gaaataactg atctgaaaat
    11101 agggtgcggg ttttcccctc accctaaccc tctccccaaa ggggcgaggg gaccgtccgg
    11161 tgcagttttt gggtttgaca tcagcctcac gggaggctgt atgtcgttaa ttaaggtgcc
    11221 ttgtatgcaa atcaccaata tgcattgcag tggacagacc gtttcacttg ccgcggggga
    11281 ttatcacgcg accattgtga ccgtcggtgc tggtctggct gaattaacct ttcagggttg
    11341 tcatttagtc atcccgcaca aacccgaaga gatgccgctg gcgcatctgg gtaaagtgct
    11401 tattccgtgg ccgaaccgga tcgccaacgg ctgttaccgc tatcaggggc aggaatatca
    11461 gttacccatt aatgaacata gttcaaaagc cgctattcac gggctgcttg cctggcgaga
    11521 ctggcaaatt agtgaattaa ccgccaccag cgttaccctg acagcttttc tgccgcccag
    11581 ttacggctat ccgtttatgc tggcttcaca agttgtttat tcgctcaacg cacacacggg
    11641 tctttccgtt gagatcgcaa gccagaatat cggcactgtc gcagcgcctt atggcgtggg
    11701 tattcatact tatttaacct gcaacttaac atctgttgat gaatatctgt tccagcttcc
    11761 ggcaaaccag gtttatgccg ttgatgaaca cgtaaatccg acaacgcttc accacgttga
    11821 tgagctggat ttaaatttca cgcaggcgaa aacaatagcc gcgacaaaaa tcgaccacac
    11881 ctttaaaacc gctaatgatc tgtgggaaat aaccattacc catccacaac aggcgctttc
    11941 ggttagcctt tgttgcgatc aaccctgggt acaaatttat agcggtgaaa aattacagcg
    12001 tcagggactg gcagttgaac ctatgagttg cccgcctaac gcctttaatt caggtatcga
    12061 cttattatta ctggaaccag gaaaaccgca ccgcctgttt tttaacattt acggacagag
    12121 aaaataactt gtattgatta gcagtcaaaa tcattgaaga acatttcact cgctaaaggc
    12181 aacattatgt atcttcaatt tattaagtta aaaacagctc agcttctgta aagtttttat
    12241 atatcagttt tatgagaatc attttacata agcctgtaat aacaggaagg caacaatctc
    12301 gttctcaact ctatggagat tagttatgga tacgccacgt ccacagttat tagattttca
    12361 atttcatcag aataacgaca gttttaccct acattttcaa caacgtctta ttttaaccca
    12421 tagcaaagat aatccttgtt tatggattgg ctcaggtata gcggatatcg atatgttccg
    12481 cggtaatttc agcattaaag ataaactaca ggagaaaatt gcgcttaccg acgccatcgt
    12541 cagccagtca ccggatggtt ggttaattca tttcagccgt ggttctgaca ttagcgccac
    12601 gctgaatatc tctgccgacg atcagggccg tttattgctg gaactacaaa acgacaacct
    12661 taaccacaac cgtatctggc tgcgccttgc cgctcaacca gaggaccata tctacggctg
    12721 cggcgaacag ttttcctact tcgatctgcg tggcaaaccg ttcccgctat ggaccagtga
    12781 acaaggcgtt ggtcgcaaca aacaaaccta tgtcacctgg caggccgact gcaaagaaaa
    12841 tgcgggcggc gactattact ggactttctt cccacagcct acgtttgtca gcacgcagaa
    12901 gtattactgc catgttgata acagttgcta tatgaacttc gactttagtg ccccggaata
    12961 ccatgaactg gcgctgtggg aagacaaagc aacgctgcgt tttgaatgtg ctgacacata
    13021 catttccctg ctggaaaaat taaccgccct gctgggacgc cagccagaac tgcccgactg
    13081 gatttatgac ggagtaacgc tcggcattca gggcgggacg gaagtgtgcc agaagaaact
    13141 ggacaccatg cgtaacgcgg gcgtgaaggt caacggcatc tgggcgcagg actggtccgg
    13201 tattcgtatg acctcttttg gcaaacgcgt gatgtggaac tggaagtgga acagcgaaaa
    13261 ctacccgcaa ctggattcac gcattaagca gtggaatcag gagggcgtgc agttcctggc
    13321 ctatatcaac ccgtatgttg ccagcgataa agatctctgc gaagaagcgg cacaacacgg
    13381 ctatctggca aaagatgcct ctggcggtga ctatctggtg gagtttggcg agttttacgg
    13441 cggcgttgtc gatctcacta atccagaagc ctacgcctgg ttcaaggaag tgatcaaaaa
    13501 gaacatgatt gaactcggct gcggcggctg gatggctgac ttcggcgagt atctgcccac
    13561 cgacacttac ctgcataacg gcatcagcgc cgaaattatg cataacgcct ggcccgcgct
    13621 gtgggcgaaa tgtaactacg aagcccttga agaaacgggc aagctcggcg agatcctttt
    13681 ctttatgcgc gccggttcta ccggtagcca gaaatactcc accatgatgt gggcgggcga
    13741 ccagaacgtc gactggagtc tcgacgatgg cctggcgtcg gttgtcccgg cggcgctgtc
    13801 gctggcaatg accggacatg gcctgcacca cagcgacatt ggcggttaca ccaccctgtt
    13861 tgagatgaag cgcagcaaag agctgctgct gcgctggtgc gatttcagcg ccttcacgcc
    13921 gatgatgcgc acccacgaag gtaaccgtcc tggcgacaac tggcagtttg acggcgacgc
    13981 agaaactatc gcccattttg cccgtatgac ctccgtcttc accaccctga aaccttacct
    14041 gaaagaggct gtcgcgctga atgcgaagtc cggcctgccg gttatgcgcc cgctgttcct
    14101 gcattacgaa gacgatgcgc acacttacac cctgaaatat cagtacctgt taggtcgcga
    14161 cattctgatc gctccggtgc atgaagaagg ccgtagcgac tggacgctct atctgccgga
    14221 ggataactgg gtccacgcct ggacgggtga agcgttccgg ggcggggaag ttaccgttaa
    14281 tgcgcccatc ggcaagccgc cggtctttta tcgcgccgat agcgaatggg cggcactgtt
    14341 cgcgtcgtta aaaagcatct aatcacatcc gcccgtgggg aaactcatgg gcaaagggag
    14401 aacatcgatg agtcacatca caacggaaga tccagcaact ttacgcctgc cctttaaaga
    14461 gaaactctct tacggtattg gcgacctggc ctctaacatc ctgctggata tcggtacact
    14521 ttatcttttg aagttttata ccgacgttct ggggctgcca ggcacctatg gcggcattat
    14581 ctttttgatt tcaaaattct ttactgcgtt taccgatatg ggtaccggca ttatgttgga
    14641 ttcccgacgc aagatcggtc caaaaggtaa gttccgtcct tttattctgt atgcgtcatt
    14701 cccggtcacc ttactggcga tcgccaactt tgtcggcaca ccgtttgatg tcaccggtaa
    14761 aacggtgatg gccactattc tgtttatgct ttacggactg tttttcagca tgatgaactg
    14821 ctcctacggc gcaatggttc ccgctatcac caaaaacccc aacgaacgcg cctcactggc
    14881 ggcatggcgt cagggcggcg ctacgctggg cctgctgctg tgcacggtgg gattcgtgcc
    14941 agtgatgaat cttatcgagg gtaatcagca acttggctat atcttcgccg ccacgctgtt
    15001 ttcactgttc ggcctgctgt ttatgtggat ctgctactca ggcgtgaaag agcgttatgt
    15061 cgaaacccaa ccaaccaatc cggcgcaaaa gcctggcctg ttgcaatctt tccgcgcaat
    15121 tgccggtaac cgcccactgt tcattctgtg tattgccaac ctctgcacct taggggcgtt
    15181 taacgtcaag ctcgccattc aggtctatta cacccagtac gtacttaacg atcccatcct
    15241 gttgtcgtat atgggatttt tcagcatggg ctgtattttc atcggcgtgt tcctgatgcc
    15301 tggcgcagtc agacgttttg gtaagaagaa ggtctatatc ggcggcctgc tgatttgggt
    15361 gctgggcgat ctgctcaact atttcttcgg cggcggctcg gtcagctttg tggcgttctc
    15421 ctgcctggcg ttcttcggct cagcgtttgt taacagcctg aactgggcgc tggtttccga
    15481 caccgtcgag tacggcgagt ggcgcaccgg cgtgcgttcg gaaggcacgg tctacaccgg
    15541 cttcaccttc tttcgcaaag tgtctcaggc gctggctggt ttcttccccg gctggatgct
    15601 gacgcaaatt ggctatgtgc cgaacgtcgc acaggctgac cacaccattg aagggttacg
    15661 ccagttgatc ttcatctacc caagcgcact ggcggtagtc accattgtgg cgatgggttg
    15721 cttctacagc ctgaacgaga agatgtatgt ccgcattgtg gaagagatag aagcccgtaa
    15781 acgcacggcg taataataat aaacgacgcc ctgcggggcg ttataaggag tgattatgtc
    15841 tgaccataat ccactgacat taaaactgaa tctgcgggaa aaaatcgcct atggtatggg
    15901 cgacgtcggt tcgaatttaa tgctctgcat cggtactctg tatctcctca aattttatac
    15961 cgatgaatta gggatgcctg cttactatgg cgggattatc tttctggtgg cgaagttttt
    16021 taccgcgttt accgatatgc tcaccggatt tttactcgac tcgcggaaaa atattgggcc
    16081 taaaggcaaa tttcgtccct ttattttata tgcagcagtt ccggcggcgt taattgcaac
    16141 gctccagttt atcgccacca ccttttgttt gccggttaaa acgacgattg ccaccgcact
    16201 gtttatgatg tttggacttt catacagtct gatgaactgc tcgtatggtg cgatgatccc
    16261 ggcaattacc aaaaacccga atgagcgcgc gcagctcgcg gcttaccgcc agggtggtgc
    16321 aaccataggg ctattgattt gtaccgtggc gtttattccg ttgcagtcgc ttttttctga
    16381 ctcaaccgtc ggttatgcct gtgcggcact tatgttctcc attggcggct ttatttttat
    16441 gatgctgtgc tacagaggcg tcaaagagca ttatgtggac acagcgccaa ccggacataa
    16501 agccagtatt ctcaaatctt tttgcgcgat atttcgtaat ccaccattgc tggttttatg
    16561 cattgctaac ctgtgtactc tggcggcatt taatatcaaa ctggcgattc aggtctatta
    16621 cacccagtat gtgctgaatg atattaattt attgtcgtgg atgggattct tcagtatggg
    16681 atgcatcctc gtcggcgtat tactggtgcc agtaactgta aaatgttttg gtaaaaaaca
    16741 ggtttattta gctggcatgg tgctgtgggc ggtgggtgat atactgaatt atttctgggg
    16801 aagtaactct ttcactttcg tcatgttctc ttgtgtcgcc ttttttggca cggcctttgt
    16861 aaacagcctg aactgggcac tggtaccaga taccgtagat tacggtgaat ggaaaaccgg
    16921 tattcgtgcc gaaggttctg tttataccgg ttataccttc tttcgtaaaa tttctgccgc
    16981 acttgctggc ttcttgccag gcattatgct gacgcaaatt ggttatgttc ccaacatcgc
    17041 gcaaagcgat gcgacattac agggtttgcg tcagctcatt tttatctggc cttgtgcact
    17101 ggcaattatt gctgcattga cgatgggatt cttttacaca ctcaatgaaa aacggtttgc
    17161 attgattatt gaggaaatca accaacgcaa aaataaagag atggcgacag aagaaaaaac
    17221 ggcttccgta acgttataaa tgtcaatagc cgctatttcc attctggtgg gtggcggcct
    17281 ccctacgttt aaaaaatgga cttattatga aaaagattaa tgcaataatt ttattatctt
    17341 ctctgacctc tgcctcggta tttgctggcg catacgtcga aaacagggag gcatataatc
    17401 ttgcctccga tcagggcgag gttatgctac gtgtgggtta taacttcgat atgggcgcgg
    17461 gtattatgtt aaccaatacc tacacctttc agcgagaaga tgaactaaaa catggctata
    17521 atgaaattga aggttggtat cctttattca aaccaaccga taaattaacc atccagcccg
    17581 gtggcttaat taatgataag agtatcggtt cgggtggtgc agtgtatctg gacgtcaact
    17641 ataaatttgt accatggttt aatctgacag tacgaaatcg ctataaccat aataactata
    17701 gttcaacaga tttgagcggg gaactggata ataatgacac ctatgaaatt ggcacctact
    17761 ggaattttaa aatcaccgat aaattttcct atacatttga gccacattat ttcatacgcg
    17821 taaatgactt taatagcagc aatggaaaag atcatcactg ggaaatcact aataccttcc
    17881 gttatcgcat taatgaacac tggctgcctt atttcgaatt acgttggtta gatcgtaatg
    17941 tcgaaccgta ccaccgcgag caaaaccaga ttcgtatcgg gacgaagtat ttcttctgat
    18001 gtgaaactgc cggatgcggc gtaaacgcct tatccggcct acggttgata cggttttcgt
    18061 tggccggatt aagcacatcc ggccattaat caagcttcag ccgccagcat ctctttctta
    18121 cgttggctaa ttcgcttaac cagcattacg gaaaccaccg caccacagaa tgcgaagcag
    18181 gccataatgc caaacacgat tttgtagcca ataatccccg gatttaaatc cagaatgtag
    18241 ccatacagac tgaagcagaa catcgccgga gcgtaaccaa taaagctacc caacgccatc
    18301 gccgcgcctg ttttattttc agcaattttt gcttcgccga taggtgcaaa aaatacggct
    18361 cgctgtgtaa agactatcgc gccaaagccc agcgtacatg ccatccctaa atagaccggc
    18421 atactttcgt gcggcagcat aatcaacagt acgagcgcag cggtactgat gataaaggtg
    18481 tagcatagat atttactcgg cgatttcagg atcttatctg aaatcatgcc accaatcggt
    18541 ccaccaatca ttttcagaca gtattggtta atgatgccgt aagcccccac cagcgcaacg
    18601 ggcaatagat agatgttttt caggaatgga atgaagaatg tcaggccaca gtaaaccgcg
    18661 taaacgaaga agacgttaaa agcaataagc cagatagttt tgtctttcag caccgaggtc
    18721 atactggtgt ttttcgatgc tccgtcttct tttttcacct cgacggacgg tgcctcttct
    18781 ttgtcattca gaacaaagaa aatgataatg cctacggcaa tcacaataag ggaatagaac
    18841 cagatgcctg ctttaaaacc caataagcca ctgccaaacc aggtaaatac tgccaacgca
    18901 gaaaatgcca ccacggtatc gacaatgcca cgccctgttt cgaagaagcc aaacaaccga
    18961 ccttgttgtt cgctattgcc caatcgactc accgacttga gcaagaccgg ccagttcatc
    19021 atgtcgcaag taacgccaaa tagcgcccag acaaagagga tgccccaata ccccggcatt
    19081 gtcgtcaaat aaacacccag taatcctgtc gcaatgagtg agaatgacat ggtgtatctg
    19141 cgcggtagtt tatcggcaaa ataaatagac agaaaaaaac ccactgtcgt gacaaatgag
    19201 tttaccgaca tagcattacc aatttgacca ttggtcaaat ggaaatattc ctgcatcggg
    19261 atataaaacg catctttcag cgacggtaat ttataaattg taccgccaca caatgttaat
    19321 agactaaata acgcccattt ctttttcgtg agcataacat cccctaagcg atttttaaaa
    19381 tcaatgtttt aaaggcaata agataccgac cattcatatg gaatggtttt attaactgcg
    19441 tatgagttaa aacttattag tggttcagaa gatggtttgc ctcttgtttg atttgttgta
    19501 gtacgttacg cacatgattt atctgattaa ttgcatcttc tttttcttta cgtaaccgcg
    19561 catccagtaa atgattttct ggcaatggtg tttcactcat ctggcgataa gggatccacg
    19621 gattatcatc ttcgtcttca aagcggaacg ccggcgcata gtaatcaacc tcttcttcca
    19681 ggccatatgc cgtcacctgc ggctcatcat cacccaggca tataaggtgc gttaataacg
    19741 ctttgaacgg catatcaccc tgacctgaaa tacaggcttt atgacccagg ccacccggtt
    19801 ctttaacgat caaggcatct ttgatatgga cctgggtaat atgcggcgcc atcgttttta
    19861 aagcgtcgat gggatgctca tttgcattga tcatgttcgc aaaatcaaac agtaaggaaa
    19921 gagattccat ctcactttct ttgaccagcg acaccagctc atggcttttt aaatcttcat
    19981 gctgttcgat cgtaaaagtc aggccgctgt cctgatacgt ttcccgtaca taggcaatgt
    20041 cgttagcgat gatcgataat acgtcgcgca aattaccttc ataacgtgga taaaaacgta
    20101 cggacgatgc cccagttttc aacgcaatgg cgacggcttc gtcaatagat gccttatctg
    20161 aagcgctggt ttcaatatga atatcaaggt tcagacggcg ggctttatcc ccaaaggcag
    20221 agagttcttt atcgtccata ttaccaagag aaaaacgctc gccatccaga acatggattt
    20281 tgacgccacg tagattattt tcacttgcga tatcaagtaa atcagcaggc aacactcttt
    20341 ccagccgcat atttaaatga aaggcataag catgtaaata aagaggaaga gtgtcgacac
    20401 gttgtagaat ctttcttgcg ttatttattg tcaccataaa acacctacag attaatgatg
    20461 aggtctacgg cctcaaatcg ccaatattca atatctatct ggacaatatt gccttgctgg
    20521 tcggcgcgat gcttttcaat taagatcgct ggcatacccg cagaaccgcc aagatacttg
    20581 ctgatatcgc ccggcattct gacgggtttg aaaatcaatt tttttactac cgtctctttt
    20641 tggtagcact tttcccagac tgcagaaaat gagtggtttt caagttgttc aataaaaccc
    20701 ggagcaactt caggattaat atatgtttcg tgatagaaaa ctttatgtcc ttccagcgcc
    20761 ccccagccgg tgatgcgata gagttcagtt gatggtgtca ctgcaatcag tggcgcgagc
    20821 gtctcgggaa tatcgctggt acggtttttc tcggtaaacc cccaggaagg ttcccgccct
    20881 tgctcaattg cggcccgctg aaagctcgcc gacagctccg ggctgtaatt aaatcgcggc
    20941 tgagtcacga accacccttt acgatcctta cggaagattt tggattctgc ctcgaggttc
    21001 agcaacgcct ggcgcagcgt catacgttta atgcccagca gctctcccag ctctctttct
    21061 gaagggagtt ttccacccgg cgtagtgatg ccatctttta accaccgatc cagtttctct
    21121 tttgcatttt ctacggtgga ttgatttccc gtcattgttt aatccttttg gtttaaacca
    21181 gatgaggcat cttacgctta cgccaaaaaa gaaagcaatt aacggcgtat gactttgcag
    21241 ataattgtga caaagctctc tattgacgta accacagact tataagggag atactcgcat
    21301 tgctgagtgc tcacgacagg caaaaaaaaa cctgccatcg ctggcaggtt ttttatgact
    21361 aaaaaacgaa attaatcgtc tttcggtgcg cggttggcgc gacgacgatc gttttccgtc
    21421 aggtgacgtt tacgaatacg gatagaggtc ggggtcactt ctaccagttc gtcatcatcg
    21481 atgaactcca gagcttgttc cagagtcatg cggataggcg gaaccagaac aacggcttcg
    21541 tcagtaccgg aagcacgcat gttggtcagt ttcttaccgg tcaggcagtt tacagtcagg
    21601 tcgttagagc ggctatgaat accgataatc tgaccttcgt aaacttctgc accgtgaccg
    21661 aggaacagct taccgcgatc ctgcagaccg aacagcgcga acgcgaccgc tttaccctga
    21721 ccgttagaga tcagtacgcc gttctgacgc tgacccactt cacccggacg tacgtcgtcg
    21781 tagtggctga aggtggagta cagcagacca gtaccggaag tcatggtcat gaactcagaa
    21841 cggaagccaa tcagaccacg gcttgggatc acgtagtcga gacgtacgcg gcctttaccg
    21901 tctggattca tgtttttcag gtcgccttta cgttcgccca gcgcctgcat tacagaaccc
    21961 tgatgctgtt cttcaacgtc cagcgtcacg ttttcatacg gctcttgttt acgaccgtcg
    22021 atttcacgga agataacttt cggacgggat accgccagtt cgaaaccttc acgacgcatg
    22081 ttttcgatca gaacagacag gtgcagttcg ccacgaccag aaacgcggaa cgcatcggcg
    22141 tcttcggttt cttctacgcg cagcgcaacg ttatgtacca gttctttgtt cagacgatcc
    22201 aggatctgac gagacgttac gaacttacct tctttaccgc agaacggcga ggtgttaacg
    22261 cagaagaaca tagaaacggt cggctcatca acggagagtg ccggcagcgc ttcaacgttt
    22321 tgcgtgtcgc aaacggtgtc agaaatgttc agttcgccaa ggcccgtgat cgccacgata
    22381 tcgccagctt ccgccagatc ggtttcgata cgttccagac cgaggtggcc cagcacttta
    22441 ccgactttcg cgttgcgggt tttgccttcg ctatcgatga tagtgacctg ttggttcggc
    22501 ttcactttac cgcgcttgat gcggccaatg ccgataacgc caacatagct gttgtaatcg
    22561 agctgagaaa tctgcatctg gaacggaccg tcaaggtcaa cgtccggcgc aggaacgtga
    22621 tcaacaatcg cctgatacag cggggtcatg tcttccgcca tatcttcgtg gtccagaccc
    22681 gcgataccgt tcagcgcaga agcgtaaacg atcgggaagt ccagctgctc gtcggtcgcg
    22741 tcgaggttaa cgaacagatc gaatacctga tccacaaccc aatcaggacg cgcgccaggg
    22801 cggtcaactt tgttgataac aacaatcggc ttcaggccgt aagcaaacgc ttttttggtt
    22861 acgaagcgcg tttgcggcat cgggccgtca aatgcgtcaa ccaccagcag cactgagtct
    22921 accatggaca ttacacgttc aacttcacca ccgaagtcgg cgtgccccgg ggtatcaacg
    22981 atgttgatac ggtaatcatt ccatttgata gcggtgtttt tcgcgaggat ggtaatccca
    23041 cgctctttct ccaaatcgtt ggagtccatc acgcgctctt gggtttcggc acgagagtcg
    23101 aacgtaccgg attgttggag cagcttgtct accagggtgg ttttaccatg gtctacgtgc
    23161 gcgatgatgg cgatattacg caatttttcg atcacaactt tgcctcaggc attagaaata
    23221 gcgcgttatt gtacacggat taatcgcact acaaaacagg atcacaaaca tcctccgcaa
    23281 acaagtattg cagagtccct ttgtgatcgc tttcacggag cataaaaagg gttatccaaa
    23341 ggtcattgca ccaacatggt gcttaatgtt tccattgaag cactatattg gtgcaacatt
    23401 cacatcgtgg tgcagccctt ttgcacgatg gtgcgcatga taacgccttt taggggcaat
    23461 ttaaaagttg gcacagattt cgctttatct tttttacggc gacacggcca aaataattgc
    23521 agatttcgtt accacgacga ccatgaccaa tccaggagag ttaaagtatg tccgctgaac
    23581 acgtactgac gatgctgaac gagcacgaag tgaagtttgt tgatttgcgc ttcaccgata
    23641 ctaaaggtaa agaacagcac gtcactatcc ctgctcatca ggtgaatgct gaattcttcg
    23701 aagaaggcaa aatgtttgac ggctcctcga ttggcggctg gaaaggcatt aacgagtccg
    23761 acatggtgct gatgccagac gcatccaccg cagtgattga cccgttcttc gccgactcca
    23821 ccctgattat ccgttgcgac atccttgaac ctggcaccct gcaaggctat gaccgtgacc
    23881 cgcgctccat tgcgaagcgc gccgaagatt acctgcgttc cactggcatt gccgacaccg
    23941 tactgttcgg gccagaacct gaattcttcc tgttcgatga catccgtttc ggatcatcta
    24001 tctccggttc ccacgttgct atcgacgata tcgaaggcgc atggaactcc tccacccaat
    24061 acgaaggtgg taacaaaggt caccgtccgg cagtgaaagg cggttacttc ccggttccac
    24121 cggtagactc ggctcaggat attcgttctg aaatgtgtct ggtgatggaa cagatgggtc
    24181 tggtggttga agcccatcac cacgaagtag cgactgctgg tcagaacgaa gtggctaccc
    24241 gcttcaatac catgaccaaa aaagctgacg aaattcagat ctacaaatat gttgtgcaca
    24301 acgtagcgca ccgcttcggt aaaaccgcga cctttatgcc aaaaccgatg ttcggtgata
    24361 acggctccgg tatgcactgc cacatgtctc tgtctaaaaa cggcgttaac ctgttcgcag
    24421 gcgacaaata cgcaggtctg tctgagcagg cgctgtacta cattggcggc gtaatcaaac
    24481 acgctaaagc gattaacgcc ctggcaaacc cgaccaccaa ctcttataag cgtctggtcc
    24541 cgggctatga agcaccggta atgctggctt actctgcgcg taaccgttct gcgtctatcc
    24601 gtattccggt ggtttcttct ccgaaagcac gtcgtatcga agtacgtttc ccggatccgg
    24661 cagctaaccc gtacctgtgc tttgctgccc tgctgatggc cggtcttgat ggtatcaaga
    24721 acaagatcca tccgggcgaa gccatggaca aaaacctgta tgacctgccg ccagaagaag
    24781 cgaaagagat cccacaggtt gcaggctctc tggaagaagc actgaacgaa ctggatctgg
    24841 accgcgagtt cctgaaagcc ggtggcgtgt tcactgacga agcaattgat gcgtacatcg
    24901 ctctgcgtcg cgaagaagat gaccgcgtgc gtatgactcc gcatccggta gagtttgagc
    24961 tgtactacag cgtctaatag ttgaagttgt actacccggc gcaacaacgc cgggatttag
    25021 ttgccgtgga aactttcagc ccatctctgc atgggctttt ttctccgtca attctctgat
    25081 gcttcgcgct ttttatccgt aaaaagctat aatgcactaa aatggtgcaa cctgttcagg
    25141 agactgcttt atggcaacag gcacgcagcc cgatgctggg cagatcctca actcgctgat
    25201 taacagtatt ttgttaatcg atgacaacct ggcgatccat tacgccaacc ctgccgcgca
    25261 acaactgctc gcccaaagct cccgcaaatt gtttggtaca ccgttaccgg aactgttgag
    25321 ctacttctca ttaaatatcg agctgatgca agaaagtctg gaggcggggc aaggttttac
    25381 cgataacgaa gtgacgctgg tcatcgacgg gcgctcgcat atcctttctg tgacggccca
    25441 gcgtatgccg gacggcatga tcctgctgga gatggctccg atggataacc agcgccgctt
    25501 aagtcaggaa cagctacagc acgcccagca ggttgctgcc cgtgatttag tgcgcggcct
    25561 ggcacatgag attaaaaatc cgcttggcgg tttacgtggc gcggcgcagc tactcagcaa
    25621 agcgttacct gacccatcac tactcgaata taccaaagtg attatcgaac aggcggaccg
    25681 gctgcgaaat ctggtcgacc gtctgttggg gccgcagctg cccggtacgc gcgttaccga
    25741 aagtattcac aaagtagctg aacgcgtggt aacgctggtg tcgatggaac tgccggacaa
    25801 cgtgcggttg attcgtgatt acgatcccag cctgccggaa ctggcgcacg acccggatca
    25861 aattgaacag gtcttgctga atattgtgcg caatgcgcta caggcgctgg ggccggaggg
    25921 tggtgaaatc attctgcgta cccgcaccgc gtttcaactg accttacacg gcgagcgcta
    25981 ccggctggcg gcgcggattg atgtggaaga taacgggccg ggcattccgc ctcatttgca
    26041 ggatacgctg ttttacccga tggtcagcgg ccgcgaaggt ggcaccgggc ttggcttatc
    26101 catcgcccgt aatttgattg atcagcattc aggcaaaatt gaatttacca gttggccagg
    26161 tcataccgag ttctcggttt acctgcctat caggaaataa aggtgacgtt tatgcaacga
    26221 gggatagtct gggtagtcga tgacgatagt tccatccgtt gggtgcttga acgtgcgctc
    26281 gctggagcgg gtttaacctg tacgacattt gagaacggcg cggaagtact ggaggcgctg
    26341 gcgagcaaaa cgccggatgt gctgctttca gatatccgta tgccgggaat ggacgggctg
    26401 gcgctgctca agcagattaa acagcgccat ccaatgcttc cggtcatcat tatgaccgca
    26461 cattccgatc tggatgctgc cgtcagcgcc tatcaacaag gggcgtttga ttatctgccc
    26521 aaaccgtttg atatcgacga agccgtcgcg ctggttgagc gcgccatcag tcattaccag
    26581 gaacagcagc agccgcgtaa tattcagctt aacggcccaa cgaccgatat catcggcgaa
    26641 gcgccagcca tgcaggacgt gttccgtatt atcggtcggc tttcgcgttc ttctattagc
    26701 gtgctgatta acggcgaatc cggcaccggt aaagaactgg tcgctcatgc cctgcatcgc
    26761 cacagtccgc gcgccaaagc gccgtttatc gcgctgaata tggcagctat cccaaaagat
    26821 ttgatcgaat cagaactgtt tggccacgag aaaggcgcgt ttactggcgc gaataccatt
    26881 cgtcaggggc gttttgaaca ggccgatggc ggtacattat tcctcgacga aattggtgat
    26941 atgccgctgg atgtgcagac gcgtttgctg cgcgtgctgg cagacggtca gttttaccgc
    27001 gttggcggct atgcgccggt gaaagtggat gtgcggatta tcgctgccac tcaccagaat
    27061 ctcgaacagc gagtgcagga aggtaagttc cgtgaggatc tgttccaccg cctgaacgtt
    27121 atccgcgttc atctgccgcc gctgcgcgaa cgtcgggaag atattccccg tctggcgcgc
    27181 cattttttac aggttgccgc gcgcgaactg ggcgtagaag cgaagttact gcatccggaa
    27241 accgaagctg ctctgacgcg tctggcgtgg ccaggcaacg tgcgccagct ggaaaacacc
    27301 tgccgctggc taacggtgat ggccgccggg caggaagtgt tgattcagga tttgcccggc
    27361 gaactgtttg aatcaacggt tgcggagagt acttcgcaaa tgcaaccgga cagctgggcg
    27421 acgcttcttg cgcagtgggc agacagagcg ctgcgttccg gtcatcaaaa tctgctttcc
    27481 gaagcgcagc cagagctgga gcggacgtta ctgacgaccg cgttgcgaca tacgcagggg
    27541 cataaacagg aagcggcgcg gctactcggc tggggccgca acaccctgac gcgtaagtta
    27601 aaagagctgg ggatggagtg attcacagct tgtgtgtaaa gattgattat tgagcgcaaa
    27661 ttgctggtat tttacgcttt actgttccga taagttcagt atgatcttgc ccggaaaacg
    27721 gggagagtca ttatgctgga atcaataatt aatctggtat cgagtggcgc agttgacagc
    27781 cacacaccgc aaactgccgt tgctgccgtg ctgtgtgccg caatgattgg gctgtttagt
    27841 tgagtttcag attgctgatg aagtgctctt tgttcatgcc ggatgcggcg tgaacgcctt
    27901 atccggccta caaaagcaat attttcaaca ggttttgtag gcctgataag cgtagcgcat
    27961 caggcaatct tgttctcagc acattgatgg cgctttcgtt ttctactttg taaacgaagc
    28021 gccattcact atttaaatca cccgtgagaa ctgctgcatc cgcgctttct ggcgcagata
    28081 ggtatcaaag cacatgcaaa tgttgcggat cagcaagcga cctttcgccg tcacctgtat
    28141 tcccttctca tccacatcca ccagcccatc ttttgctaac ggggcgagca gcttgagatc
    28201 ttccgcaaag taatcagcga agtgcaaatc ccactgtttc tcaatagggg cgtaatccag
    28261 acggaagttg cagatgagcg acttaatcac atcgcggcga atacagtcat cacgcgttag
    28321 cgcaatacca cgccacagcg cattgccttg ttcatccact tgctgatagt actgcttcaa
    28381 ctctttctgg ttctgcgcgt agcagtcgcc aatcatgctg atggcggaaa cgcccatccc
    28441 cagcagatcg gtatcgccct gagtggtgta gccctggaag ttacgatgca gcacgccttc
    28501 acgctgggcc accgccagct cgtcatccgg acgggcaaag tgatccatac cgataaactg
    28561 atagcccgat tgcgtcagga aggcgatggt ttcctgcagg atatcgagtt tttgctgcgg
    28621 actcggcagg tcagcatctt tgattttgcg ctgagcagca aaaatggtcg gcagatgcgc
    28681 gtagttaaag acactcagac gatcggggtt cagctccgcc acacgtttca gggtaaaggc
    28741 gaaactctcc ggcgtctgtt tcggcaggcc gtaaatcagg tcgatgttgg tggaggtaaa
    28801 accaatctca cgcgcatggt taagcagtgc aaagatgaac tcttcatcct gctcgcggtt
    28861 aaccagacgt tgcacttctt tgttgaagtc ctgcacgccc atgctcaggc gattaaagcc
    28921 ttcggcgcgt aaatgatcga gtacatccag ttcgatttcc cgcggatcga cttcgatcga
    28981 aatctccgca tcggcattga actggaagtt ttcgcgcagc agcttcatca ggcggctgat
    29041 ttgcgcttta ttcagatacg tcggcgttcc gccgccccag tgcaattggc tgacgtgacg
    29101 cccggcgaac agcggtgcac gatggacgat ttcttgctcc agcgcgtcca gatactgatc
    29161 ggccttgtgc tgctggcgag taacaatctt attgcaaccg cagaagtaac aaagcttatg
    29221 gcagaacggg atatgtacgt agagagataa tggacgctca ggatagcgcg ccacggcttg
    29281 taaaaacgcc tgttcgccga agtcttctga aaactccagc gcggtcgggt acgaggtgta
    29341 tcgtggcccg gaatagttat atttctggat cagggccaga tcccagtcga tttgctgtac
    29401 agacatgctc actccttccg atggcgtctc tggcggctac ggcgtaccgg cggatgcccg
    29461 tttcgggtca ttagccggtt gcgcagccac ttttgtcgcc gcgacaaccg ctgtagttta
    29521 acgaataacc acaccagata acatataacc ggaagggtta tcagcagaac gggaaggccc
    29581 acggcggcaa tccgttagtt gccccgcagc agacgcatca tgtcttcttg cttctcgtct
    29641 tcttcctctt cttcgtcatc gtcataagag aggccgagtt tctgcatcaa ctcatcaata
    29701 cgatccagtt tagcatccac ccaggattgc tcttcggcac tcagggtttc gcctgcttcc
    29761 agacgttcca gcagcgcatc cagacgctca tccgtttcca gtaattccaa ctccgcctgc
    29821 ggtgaaagca taggtttctc actcttcggt ttgtgctgtt tggtgacttt ttcagtcacg
    29881 cccaatggaa taggggtttt actgccaata cgtggatctt ttggtgcgtt ctggcctttg
    29941 ctgcctgacg tggtgtttcc gcccgctgcg cggctgcccg gcgcatgacc acgacgtttt
    30001 ttctgacgct tgcgatcacg agcttcctga tccagctcct cgcgtgtttt tcgacgcgct
    30061 tttgcatgac ctttgctgcg tgagtttgaa gatgatggtt tcataatggt tcgtctttta
    30121 gccgttttat tcagtataga tttgcggcgg aatctaacag aaagcaagca aagaaaaaag
    30181 gcgacagatt actctgtcgc cttttttcct gactcataac ccttaacggg tcttacaatc
    30241 cttgcaggcc gccaacacac cctgtttttc ctttagccgg aacaatccgt gttgattcca
    30301 tttccgttta attacgtctc cggacgtttg tcttcctgac aatcctctgt cttcgcctcc
    30361 tggcgctcct gaccctcatc ctgagtcatt gttcctgtta gcgtcctcgc tctatgggtg
    30421 ctactttacg cctttgcttt aaacaaacaa tcaaccgcca tcagtatttg cacattttca
    30481 gagttttata taaaagcaat tcactgattt atatagctta tttgacatgc atcgcagaat
    30541 tttctctgct atttcgcata aagactatcg gcaatgtctc acaaagcgta tggcttttac
    30601 ttacaacgct cacgccgaaa aatccgcctt ttattatggt tcaggtataa tcgccacaaa
    30661 gctttgactg acggagacga ccgctttgac taatttgaat tatcaacaga cgcattttgt
    30721 gatgagtgcg cctgatattc gccacctacc ttccgatacc ggaattgaag tggcttttgc
    30781 aggccgttcc aacgcaggta aatccagcgc gctgaacacg ctgactaacc agaaaagcct
    30841 ggctcgtacc tcaaaaaccc cagggcgcac ccagcttatc aacctgtttg aagtggctga
    30901 cggcaagcgt ctggttgact tgcctgggta cggttatgcg gaagtcccgg aagagatgaa
    30961 gcgcaaatgg cagcgtgcgc tcggcgaata cctcgaaaaa cgtcagagcc tgcaaggtct
    31021 ggtggtgcta atggatattc gccatccgct gaaagatttg gatcagcaga tgattgagtg
    31081 ggcggtagac agcaatatcg ccgttctggt gctgctgacc aaagcggaca aactggcaag
    31141 cggcgcacgt aaagcgcaat tgaatatggt gcgtgaagct gtactggcgt ttaacggtga
    31201 tgtgcaggtt gaaacgtttt cttcgttgaa gaaacaaggc gtggacaagc tgcggcagaa
    31261 actggatacc tggtttagcg agatgcagcc tgtagaagaa acgcaggacg gcgaataatt
    31321 ttcttgcctt aatgcttgtg ccggatgtgg cgtatccggc ccgtaaattc aatagattac
    31381 aattctaccg ttggcctgat aaacatagcg catcaggcat tacggatctt ttctttcgcc
    31441 caataaaaaa cgccccagtc attactgact ggggcggcta aaatattcag ccaaatccga
    31501 ttacgtgaag taaaaggtct gaaagataga acatcttacc tctgtaccct acgcgactaa
    31561 ctttactctt ttttgttcag ttcagaaagc actttttgta attttttttc agttgttgca
    31621 taggaatttc taatagccat cacaaaacgt gacagcttat gttgcttact tacgaaaaaa
    31681 gggcatgttc aggcgaatct tagtgcgcct gatcccagtt ttcgccactc cccacttcca
    31741 ccagcaacgg cacatccaga cgggtacagt tttccatcag ttgatgaatc tgcttcgcga
    31801 cggcatcaac atcatcttta tgaacttcaa ataccagttc atcgtgtacc tgcatgatca
    31861 tacgtacacg cggttgctca gcctgtaacc acgcatcaac ggcaatcatc gcccgtttga
    31921 taatgtcggc ggcggttccc tgcattggcg cgttaatggc tgcacgttca gccgctgcac
    31981 gacgagcacc attgctggat ttgatatccg gcagatacag acggcgtccg tccagcgttt
    32041 caacgtagcc ctgctctttc gcctgagcac gggtgcgttc catatactcc agcacgccag
    32101 ggtagcgttc gaagtaaagg tccatgtact tctgcgcttc tttacgtgga atgttcaatt
    32161 gccgcgccag accgaaagca ctcatgccat aaatcagacc aaagttgatc gctttcgcgc
    32221 tacggcgttg ctcgctggtg acggtttcca gtggcaaacc aaacacttct gccgccgttg
    32281 cccggtggat atcttttcct tccgcgaatg cggtcagcaa gcctttgtca cgcgaaagat
    32341 gcgccataat gcgcagttca atctgcgagt agtccgctga gacaatcaca taatcctctg
    32401 gcgcaataaa cgcctggcgg atacgacgac cttcttcgtt acgcaccgga atgttttgca
    32461 ggttaggatc ggttgacgat aaacgtcccg ttgcagttac tgcctggtga taagaggtat
    32521 gcacacgccc ggttttcggg ttgatcatca gcggcagctt gtcggtgtag gtcgatttca
    32581 gcttcgccag accacgatac tccagaatca cttttggcaa cggatagtcc agcgccagtt
    32641 cttccagtac ctcttccgac gttgacggcg cgccacccgg cgttttcttc agcggtttaa
    32701 taccctgttt ttcaaagaga atggtttgca actgcttggt ggaagaaagg ttaaattctt
    32761 cacctgcaat ttcatgcgct ttcttttcca gctcagccag acgcaaggtg agctcttcag
    32821 aatgattgtg cagcactttc ggatcgatct tcacaccgtt acgttcaatg cgtgaaagca
    32881 ccggcaccag cggcatttcg atattctcga agacgttcaa cggccctttg tgtttttgca
    32941 gatctggcca cattttcaga tgcaactgca aggtgacatc agcatcttcg gcggcgtaac
    33001 gtccggcctc ttcgagggca atctggttaa aggtcagttg atttttgcct ttacccgcaa
    33061 tctcttcaaa agtgatggtt ttgtgcttca accaacgttc cgcgaggctg tccatatcgt
    33121 gacgcccggc aacgctattg agaatgtagg actccagcat ggtatcaaac gcaatcccac
    33181 gcagctcaat gccgtaattc gccagaatac cgcgatcgta tttcaggttt tgcccgacct
    33241 tcagcgcctt ttcatcttcc agcagcggtt ttagcaactc gagtgcacgc tcgcgagaga
    33301 tttgatcggg cgcgtcaaga taatcatgag caaccggaat atatgccgct acgcctggct
    33361 cgatagcaaa agaaagcccg accaggttag cagagatgtt atcaaggctg tcggtttcgg
    33421 tatcaaatgc aaataccggc gctttttcca gcttcgcaat ccacgctttc agtgtttctt
    33481 catcaaggat ggtgacgtag ttgtcataag aaatcaccgt tgccgtcact tctggcgctt
    33541 cgtctgcaac actggtttcc tgtggcttcg cggctggttt tgcccctttg gcctgtaacc
    33601 atttgcccgc ttcgacatca gcagtccagc gtttgaactc atactttttg aacagcccca
    33661 acaactcttc cgctgccggt tgctgcactt ccagttgttc acaggtcagc tccagttcaa
    33721 cgtcggtttt aatcgtcgcc agctggtatg agagataagc aacttctttg ttttgctcga
    33781 gcttcgctgc cattgttttc gcgccacgga agctcaaccc agcaattttt tctggctcgg
    33841 catacagcgt atccagtccg ccaagacctt gcagcaatgc ctgcgcggtt ttttcaccga
    33901 cgcccggtac gccaggaatg ttatcagagg agtcacccat cagcgccagg aaatcgatga
    33961 tcagttctgg cggcacgccg tacttattca ccacctcttc cggtccgagg atggtattcg
    34021 tcatggtatt gataagcgta atatttggcg tcaccagctg cgccatatct ttatcgccag
    34081 tgctgatcag caccggacgc ccggcttttt cggcttcgcg cgccagagta ccgataacgt
    34141 cgtccgcttc tacgccagaa accgccagca gcggcagtcc catcgcttta accatcgcgt
    34201 gcaagggttc gatttgtgca cgcagatcgt ccggcattgg cgggcgatgt gatttgtaat
    34261 gttcaaacag ttcatcacga aaggtttttc ccttggcgtc aaagaccacc gctgcatgcg
    34321 tcggtttata ttgcatgatc agactgcgca gcatgttgag gacaccatac atcgcaccgg
    34381 tcggctcgcc tgcgctgtta gtcagcgggg gaaacgcgtg atatgcgcga taaagataag
    34441 atgaaccatc tacaaggata agtggatttt gggggatctg aaccataatg tccgtgcctg
    34501 tttatcagat tatgggtaaa ggatgccaca gacaggatga aaacatgagt ttttcaccgc
    34561 ttttcgtgaa aatcttttgt agatcttctg gatcgctcgc aaatcgtcat gtggataact
    34621 ttgtgcataa attatttaca tcgcttttaa tttattatca tgctttttac agcatgatgt
    34681 ttgtctttgt ttttcatgca gttaaaaata aatccatccc taataattga gataatggga
    34741 ttttttctaa tgtggataga tatgaattat ttttctcctt aaggatcatc cgttatttgg
    34801 gtcgttttct gctaaaatct gcgccttgcg cttctttagc gcactgtcta tggctaacct
    34861 tttgaataaa ttcattatga cgagaatact cgctgcgata acccttttgc tgagtatcgt
    34921 attgaccatt ttggtcacta ttttttgttc cgtcccgatc atcattgccg ggattgtaaa
    34981 actattgcta cctgtgccag tcatttggcg aaaggtttcg cgtttttgtg attttatgat
    35041 gtattgctgg tgtgaaggtc tggcggtatt actgcatctg aacccacacc tgcaatggga
    35101 agttcacggg ctggaagggt taagtaagaa gaactggtat ctgcttattt gtaaccaccg
    35161 tagttgggca gatattgtcg tactgtgcgt gctgtttcgt aagcacattc cgatgaataa
    35221 atatttcctc aagcaacagc tggcctgggt gccatttctt ggcctggcgt gctggtcgct
    35281 ggatatgccg tttatgaagc gttattcccg cgcttattta ttacgtcatc cggagcgacg
    35341 tggtaaagat gttgaaacca ctcggcgttc ttgtgaaaag tttcgcctgc atcccaccac
    35401 cattgtcaat ttcgttgaag gctcccgttt cacgcaagaa aaacatcagc aaacccactc
    35461 cacttttcaa aacttgttgc caccaaaggc ggcaggcatt gcgatggcgc taaatgtact
    35521 gggcaaacaa ttcgataaac tgcttaatgt tacactgtgt tatccggaca ataaccgtca
    35581 gccgttcttc gatatgttaa gcggtaaact gacgcggatt gtcgtacatg tggatttaca
    35641 gcctattgcc gatgagttac atggcgacta catcaatgac aaaagcttta agcgccattt
    35701 tcagcaatgg ctgaactcat tgtggcagga aaaagaccgg cttctgacgt ctctcatgtc
    35761 atcacagcgt cagaataagt aagttttact cgcctctgaa tgagcagagg cgagtgagta
    35821 ttttaatgaa caaaacgtcc ggcacgagac ataaattctt cttcgctcat ctcctgtccg
    35881 ttaaaaacaa ctttacccgg tgtataacgc agctgcagcg aggcggtatt gttgtcaatc
    35941 gtgattaact gaaacatctg acccaatgtc atcatcccgc tgatttgttt atcagcctgc
    36001 ttttgcgctt tttccgcatc cattccttca gataaattaa gctgttttgc ggtttctgtg
    36061 acgacattaa gcggtaactt cacatcaaaa ttgagcgatt tgatatcttt gtttgtggat
    36121 gatgaagatt tggctgggtc ggcaatactg atatccagat tggcatttag ttcgccgagt
    36181 gcgttcttcc atcttaccgg ttgtttaatg gtcggctcac ttttttgtaa taacggtaaa
    36241 tactctttga acaatgcagc attcacttct tgcagagcaa cttcatcgtt tgctaactca
    36301 gggtgtacag caagctgctt ctgcatagca atgttatact ggatgataaa ttggcgcact
    36361 gctgagggat caatagattc agcaatcaat gaccactcac cactaccgag ttgctgattc
    36421 ccttttgtta acttatcaag ttcgtaggtc agattgacat tgatataatc tttgtcttta
    36481 acgcgatcca gcatggtttt tgcaacgaaa gcatcgattt gggcaacgtc ttccccgtga
    36541 ttgataatgt taatctgatt aaatttcgac tcgctttcac caaccggaaa tttcttttct
    36601 tctaatcgcg ccagagaatc aatggtaaaa ctttttgccg ttactttgtt cattggtgat
    36661 aattgcagaa caatatcttc gactttgcct tcaatatcca ggttagacaa tgaactacca
    36721 tcaccattaa aagtaaactg gccctcacca aaagaaaact ttccatactc tgcaggggca
    36781 acctctaatg tcgtagagaa tgagccacca aacgcgaatc gcaatgtcgc ttccacgggc
    36841 gatttatttt tcgcggcgat aaatagcggt tgtgtcagtt cattattcac taagttcact
    36901 tttgccgctg ccagtgctgg gatgacatta ccatgcatta acattgtgat gggcaacgga
    36961 ccgtgctcaa catccacatc aaatacaact ttctggcctg gcttgatatt gagatcgggt
    37021 gcaccgttat cgaatgtcat ttgcatttga aaacgggaat taaaaaagcc tttgtcaaaa
    37081 ttttgataac ttaacgtcat atcgtaggca tgttcacctt tctttttagc atcgttaaaa
    37141 tctttaataa atttttcgac accaggctga atttgtgtac ctgtgtacca tgtgccacca
    37201 ccccagatta cggctaacgc aacaataaca cctgtagctg acttacgtat catataaata
    37261 ttccctgata aaacagcaaa actttgaata tcca
//
LOCUS       DAZUDJ010000049        36805 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.049, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000049 DAZUDJ010000000
VERSION     DAZUDJ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36805
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.049"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            315..1883
                     /gene="cydA"
                     /locus_tag="ACHY1N_003181"
     CDS             315..1883
                     /gene="cydA"
                     /locus_tag="ACHY1N_003181"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415261.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0070069 - cytochrome complex [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HFS4045452.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPD
                     QEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSSTTTQPAR"
     gene            1899..3038
                     /gene="cydB"
                     /locus_tag="ACHY1N_003182"
     CDS             1899..3038
                     /gene="cydB"
                     /locus_tag="ACHY1N_003182"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HFS4045453.1"
                     /translation="MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGN
                     FFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALA
                     GVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLP
                     LLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     LTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY"
     gene            3053..3166
                     /gene="cydX"
                     /locus_tag="ACHY1N_003183"
     CDS             3053..3166
                     /gene="cydX"
                     /locus_tag="ACHY1N_003183"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HFS4045454.1"
                     /translation="MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI"
     gene            3166..3459
                     /gene="ybgE"
                     /locus_tag="ACHY1N_003184"
     CDS             3166..3459
                     /gene="ybgE"
                     /locus_tag="ACHY1N_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HFS4045455.1"
                     /translation="MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTS
                     ELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF"
     gene            3609..4013
                     /gene="ybgC"
                     /locus_tag="ACHY1N_003185"
     CDS             3609..4013
                     /gene="ybgC"
                     /locus_tag="ACHY1N_003185"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HFS4045456.1"
                     /translation="MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHH
                     FSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENT
                     LLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ"
     gene            4010..4702
                     /gene="tolQ"
                     /locus_tag="ACHY1N_003186"
     CDS             4010..4702
                     /gene="tolQ"
                     /locus_tag="ACHY1N_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HFS4045457.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            4706..5134
                     /gene="tolR"
                     /locus_tag="ACHY1N_003187"
     CDS             4706..5134
                     /gene="tolR"
                     /locus_tag="ACHY1N_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HFS4045458.1"
                     /translation="MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKAN
                     PKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            5199..6464
                     /gene="tolA"
                     /locus_tag="ACHY1N_003188"
     CDS             5199..6464
                     /gene="tolA"
                     /locus_tag="ACHY1N_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0019534 - toxin transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HFS4045459.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHVILFAALIWSSFDENIEASAGG
                     GGGSSIDAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQER
                     LKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAA
                     KKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEK
                     AKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAA
                     AAKAAAEKAAAAKAAAEADDIFGELSSGKNAPKTGGGAKGNNASPAGSGNTKNNGASG
                     ADINNYAGQIKSAIESKFYDASSYAGKTCTLRIKLAPDGMLLDIKPEGGDPALCQAAL
                     AAAKLAKIPKPPSQAVYEVFKNAPLDFKP"
     gene            6597..7889
                     /gene="tolB"
                     /locus_tag="ACHY1N_003189"
     CDS             6597..7889
                     /gene="tolB"
                     /locus_tag="ACHY1N_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system beta propeller repeat protein
                     TolB"
                     /protein_id="HFS4045460.1"
                     /translation="MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVG
                     QVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLA
                     SGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQN
                     QDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL"
     gene            7924..8445
                     /gene="pal"
                     /locus_tag="ACHY1N_003190"
     CDS             7924..8445
                     /gene="pal"
                     /locus_tag="ACHY1N_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HFS4045461.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGMLGAGTGMD
                     ANGGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSNPSYK
                     VTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDE
                     AAYSKNRRAVLVY"
     gene            8455..9246
                     /gene="cpoB"
                     /locus_tag="ACHY1N_003191"
     CDS             8455..9246
                     /gene="cpoB"
                     /locus_tag="ACHY1N_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0070206 - protein trimerization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HFS4045462.1"
                     /translation="MSSNFRHQLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVVERQKQILLQIDSLS
                     SGGAAAQSTSSDQSGAAASTTPTADAGTANAGAPVKSGDANTDYNAAIALVQDKSRQD
                     DAMVAFQNFIKNYPDSTYLPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAAD
                     AMFKVGVIMQDKGDTAKAKAVYQQVISKYPGTDGAKQAQKRLNAM"
     gene            9411..9486
                     /locus_tag="ACHY1N_003192"
     tRNA            9411..9486
                     /locus_tag="ACHY1N_003192"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9444..9446,aa:Lys,seq:ttt)
     gene            9622..9697
                     /locus_tag="ACHY1N_003193"
     tRNA            9622..9697
                     /locus_tag="ACHY1N_003193"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9655..9657,aa:Val,seq:tac)
     gene            9700..9775
                     /locus_tag="ACHY1N_003194"
     tRNA            9700..9775
                     /locus_tag="ACHY1N_003194"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9733..9735,aa:Lys,seq:ttt)
     gene            9925..10000
                     /locus_tag="ACHY1N_003195"
     tRNA            9925..10000
                     /locus_tag="ACHY1N_003195"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9958..9960,aa:Val,seq:tac)
     gene            10004..10079
                     /locus_tag="ACHY1N_003196"
     tRNA            10004..10079
                     /locus_tag="ACHY1N_003196"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10037..10039,aa:Lys,seq:ttt)
     gene            10226..10301
                     /locus_tag="ACHY1N_003197"
     tRNA            10226..10301
                     /locus_tag="ACHY1N_003197"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10259..10261,aa:Lys,seq:ttt)
     gene            10335..10410
                     /locus_tag="ACHY1N_003198"
     tRNA            10335..10410
                     /locus_tag="ACHY1N_003198"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10368..10370,aa:Lys,seq:ttt)
     gene            10659..11702
                     /gene="nadA"
                     /locus_tag="ACHY1N_003199"
     CDS             10659..11702
                     /gene="nadA"
                     /locus_tag="ACHY1N_003199"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HFS4045463.1"
                     /translation="MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEK
                     TILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
                     ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEY
                     PDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLQSIAEALEQEGSNHEVHVDERLRERALVP
                     LNRMLDFAATLRG"
     gene            11740..12459
                     /gene="pnuC"
                     /locus_tag="ACHY1N_003200"
     CDS             11740..12459
                     /gene="pnuC"
                     /locus_tag="ACHY1N_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFS4045464.1"
                     /translation="MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEK
                     ISNYFFGLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELKIR
                     WLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVMIMQALGLQVVMPELQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYIILTFIA
                     LNGSRMWINSARERGSRALSH"
     gene            complement(12456..13397)
                     /gene="zitB"
                     /locus_tag="ACHY1N_003201"
     CDS             complement(12456..13397)
                     /gene="zitB"
                     /locus_tag="ACHY1N_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005385 - zinc ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006829 - zinc ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HFS4045465.1"
                     /translation="MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGS
                     LALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVIT
                     ILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
                     LGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPV
                     SLDIAELKRRMCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYL
                     MDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH"
     gene            complement(13511..13891)
                     /gene="ybgS"
                     /locus_tag="ACHY1N_003202"
     CDS             complement(13511..13891)
                     /gene="ybgS"
                     /locus_tag="ACHY1N_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgS-like family protein"
                     /protein_id="HFS4045466.1"
                     /translation="MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQ
                     VAPDARENVAPNNVDNNGVNTGSGGTMLHSDGSSMNNDGMTKDEEHKNTMCKDGRCPD
                     INKKVQTGDGINNDVDTKTDGTTQ"
     gene            14207..15259
                     /gene="aroG"
                     /locus_tag="ACHY1N_003203"
     CDS             14207..15259
                     /gene="aroG"
                     /locus_tag="ACHY1N_003203"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HFS4045467.1"
                     /translation="MNYQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKAGLPAQVMIDFSHANSSKQFK
                     KQMDVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGEPLAYGKSITDACIGWEDT
                     DALLRQLANAVKARRG"
     gene            complement(15417..16169)
                     /gene="gpmA"
                     /locus_tag="ACHY1N_003204"
     CDS             complement(15417..16169)
                     /gene="gpmA"
                     /locus_tag="ACHY1N_003204"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFS4045468.1"
                     /translation="MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKL
                     LKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAE
                     TAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
                     VIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEF
                     DENFKPLKRYYLGNADEIAAKAAAVANQGKAK"
     gene            complement(16374..17414)
                     /gene="galM"
                     /locus_tag="ACHY1N_003205"
     CDS             complement(16374..17414)
                     /gene="galM"
                     /locus_tag="ACHY1N_003205"
                     /EC_number="5.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004034 - aldose 1-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HFS4045469.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNNAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPECYQDQAAFLGASIGRYANRIANSRYTFDGETVTLSPSQGVNQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALSSDDGDQGFPGNLGATVQYRLTDDNRISITY
                     RATVDKPCPVNMTNHVYFNLDGEQSDVRNHKLQILADEYLPVDEGGIPHDGLKSVAGT
                     SFDFRSAKIIASEFLADDDQRKVKGYDHAFLLQAKGDGKKVAAHVWSADEKLQLKVYT
                     TAPALQFYSGNFLGGTPSRGTEPYADWQGLALESEFLPDSPNHPEWPQPDCFLRPGEE
                     YSSLTEYQFIAE"
     gene            complement(17408..18556)
                     /gene="galK"
                     /locus_tag="ACHY1N_003206"
     CDS             complement(17408..18556)
                     /gene="galK"
                     /locus_tag="ACHY1N_003206"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFS4045470.1"
                     /translation="MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKH
                     LQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTV
                     EAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGG
                     GFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC"
     gene            complement(18560..19606)
                     /gene="galT"
                     /locus_tag="ACHY1N_003207"
     CDS             complement(18560..19606)
                     /gene="galT"
                     /locus_tag="ACHY1N_003207"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008108 - UDP-glucose:hexose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HFS4045471.1"
                     /translation="MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQV
                     LPAHDPDCFLCAGNVRVTGDKNPDYTGTYVFTNDFAALMSDTPDAPESNDPLMRCQSA
                     RGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQVWANSFLPNEAEREDRLQKEYFAGQKSPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFRESGV"
     gene            complement(19616..20632)
                     /gene="galE"
                     /locus_tag="ACHY1N_003208"
     CDS             complement(19616..20632)
                     /gene="galE"
                     /locus_tag="ACHY1N_003208"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308814.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFS4045472.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVN
                     GTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGSSVLDVVNAF
                     SKACGKPVNYHFAPRREGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYPD"
     gene            complement(20893..22365)
                     /gene="modF"
                     /locus_tag="ACHY1N_003209"
     CDS             complement(20893..22365)
                     /gene="modF"
                     /locus_tag="ACHY1N_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HFS4045473.1"
                     /translation="MSSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSA
                     LARALAGELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMLGPGEDDTGRTT
                     AEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
                     EPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGA
                     KEELLQQALVAQLAHSEQLEGVQLPEPDEPSARHALPTNEPRIVLNNGVVSYNDRPIL
                     NNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDK
                     RTADVPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISE
                     GETQLLFVSHHAEDAPACITHRLEFVPDGDLYRYALTKIN"
     gene            complement(22433..23221)
                     /gene="modE"
                     /locus_tag="ACHY1N_003210"
     CDS             complement(22433..23221)
                     /gene="modE"
                     /locus_tag="ACHY1N_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HFS4045474.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDV
                     LSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKV
                     AITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCE
                     VLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC"
     gene            23350..23499
                     /gene="acrZ"
                     /locus_tag="ACHY1N_003211"
     CDS             23350..23499
                     /gene="acrZ"
                     /locus_tag="ACHY1N_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump accessory protein AcrZ"
                     /protein_id="HFS4045475.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQ
                     PGQNH"
     gene            23666..24439
                     /gene="modA"
                     /locus_tag="ACHY1N_003212"
     CDS             23666..24439
                     /gene="modA"
                     /locus_tag="ACHY1N_003212"
                     /EC_number="7.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4045476.1"
                     /translation="MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDI
                     ATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQ
                     TLLGNSLVVVAPKASEQKDFIIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKL
                     GAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKV
                     EYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK"
     gene            24439..25128
                     /gene="modB"
                     /locus_tag="ACHY1N_003213"
     CDS             24439..25128
                     /gene="modB"
                     /locus_tag="ACHY1N_003213"
                     /EC_number="7.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015098 - molybdate ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HFS4045477.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGK
                     ALLDSILHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEW
                     LARISRERAGR"
     gene            25131..26189
                     /gene="modC"
                     /locus_tag="ACHY1N_003214"
     CDS             25131..26189
                     /gene="modC"
                     /locus_tag="ACHY1N_003214"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015098 - molybdate ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HFS4045478.1"
                     /translation="MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAI
                     SGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMA
                     KSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWG
                     SSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELA
                     IKPGLWLYAQIKSVSITA"
     gene            complement(26190..27008)
                     /gene="ybhA"
                     /locus_tag="ACHY1N_003215"
     CDS             complement(26190..27008)
                     /gene="ybhA"
                     /locus_tag="ACHY1N_003215"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyridoxal
                     phosphate/fructose-1,6-bisphosphate phosphatase"
                     /protein_id="HFS4045479.1"
                     /translation="MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTG
                     RHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHI
                     HGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
                     THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENV
                     VAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI"
     gene            27163..28158
                     /gene="pgl"
                     /locus_tag="ACHY1N_003216"
     CDS             27163..28158
                     /gene="pgl"
                     /locus_tag="ACHY1N_003216"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HFS4045480.1"
                     /translation="MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYN
                     AGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG
                     HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTL
                     DMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ
                     PRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH"
     gene            complement(28199..29152)
                     /gene="ybhD"
                     /locus_tag="ACHY1N_003217"
     CDS             complement(28199..29152)
                     /gene="ybhD"
                     /locus_tag="ACHY1N_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4045481.1"
                     /translation="MKHELSSMKAFVILAESSSFNNAAKSLNITQPALTRRIKKMEED
                     LHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPT
                     AVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFT
                     PLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLD
                     WFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKD
                     AVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIS"
     gene            29336..30388
                     /gene="ybhH"
                     /locus_tag="ACHY1N_003218"
     CDS             29336..30388
                     /gene="ybhH"
                     /locus_tag="ACHY1N_003218"
                     /EC_number="5.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalomesaconate tautomerase"
                     /protein_id="HFS4045482.1"
                     /translation="MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGND
                     LEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGA
                     FAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVA
                     LTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELD
                     ADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRA
                     LAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRAS
                     VIRTTRKIFSGEVYLP"
     gene            30464..31897
                     /gene="ybhI"
                     /locus_tag="ACHY1N_003219"
     CDS             30464..31897
                     /gene="ybhI"
                     /locus_tag="ACHY1N_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HFS4045483.1"
                     /translation="MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIV
                     GLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAA
                     FVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSV
                     AVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISW
                     GGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLG
                     VFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGII
                     GLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAML
                     PVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGA
                     VLTILTFLVHITLGVWWWNMLIGWNML"
     gene            32080..34341
                     /gene="ybhJ"
                     /locus_tag="ACHY1N_003220"
     CDS             32080..34341
                     /gene="ybhJ"
                     /locus_tag="ACHY1N_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydratase"
                     /protein_id="HFS4045484.1"
                     /translation="MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSS
                     HNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGT
                     INGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTM
                     AVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVK
                     NKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQL
                     NPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAH
                     GKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
                     SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREG
                     SKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQG
                     FVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRS
                     NPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPL
                     QTEIGSMVYAVKLGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQM
                     AEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIK
                     AGSLINFNKNRQM"
     gene            complement(34483..35766)
                     /gene="ybhC"
                     /locus_tag="ACHY1N_003221"
     CDS             complement(34483..35766)
                     /gene="ybhC"
                     /locus_tag="ACHY1N_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HFS4045485.1"
                     /translation="MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPI
                     LSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVD
                     AAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPA
                     DWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVT
                     NSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFN
                     AFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVD
                     DNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK"
     gene            complement(35901..>36805)
                     /locus_tag="ACHY1N_003222"
     CDS             complement(35901..>36805)
                     /locus_tag="ACHY1N_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4045486.1"
                     /translation="SGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINY
                     MSKIKAIRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEG
                     HITTNPVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDL
                     CEMKWSDIVDGYLYVEQSKTGVKIAIPTTLHVDALGISMKETLDKCKEILGGETIIAS
                     TRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQISDKFAQHLLG
                     HKSDTMASQYRDDRGREWDKIEIK"
BASE COUNT         8851 a         8983 c         9658 g         9313 t
ORIGIN      
        1 gcatcaaaaa gagataaatt gttctcgatc aaattggctg aaaggcggta atttagctat
       61 aaattgatca ccgtcgaaaa atgcaaattt gcttcaacaa aaacctgttt attgtaagga
      121 ttttgcggcg taatatatac gtgggatcaa tttgagtttt tattaacatg tttgcaacct
      181 ttctttacgc cgtttttgtg tgcattcaca tggtatgatg aaagtgttca aacaaatttc
      241 tattggggca tgcgtgtgac cctttctaac ggggttcact ctcggagtct tcatgcgatg
      301 agcaaggagt catgatgtta gatatagtcg aactgtcgcg cttacagttt gccttgaccg
      361 cgatgtacca cttccttttt gtgccactga cgctcggtat ggcgttcctg ctggccatta
      421 tggaaacggt ctacgtcctc tccggcaaac agatttataa agatatgacc aagttctggg
      481 gcaagttgtt tggtatcaac ttcgctctgg gtgtggctac cggtctgacc atggagttcc
      541 agttcgggac taactggtct tactattccc actatgtagg ggatatcttc ggtgcgccgc
      601 tggcaatcga aggtctgatg gccttcttcc tcgaatccac ctttgtaggt ctgttcttct
      661 tcggttggga tcgtctgggt aaagttcagc atatgtgtgt cacctggctg gtggcgctcg
      721 gttcaaacct gtccgcactg tggattctgg ttgcgaacgg ctggatgcaa aacccaatcg
      781 cgtccgattt caactttgaa actatgcgta tggagatggt gagcttctcc gagctggtgc
      841 ttaacccggt tgctcaggtg aaattcgttc acactgtagc gtctggttat gtgactggcg
      901 cgatgttcat cctcggtatc agcgcatggt atatgctgaa aggtcgtgac ttcgccttcg
      961 ctaaacgctc ctttgctatc gctgccagct tcggtatggc tgctgttctg tctgttattg
     1021 ttctgggtga tgaatccggc tacgaaatgg gcgacgtgca gaaaaccaaa ctggctgcta
     1081 ttgaagccga gtgggaaacg caacctgcgc ctgctgcctt tactctgttc ggcattcctg
     1141 atcaggaaga ggagacgaac aaatttgcga ttcagatccc ttacgcactg ggcatcattg
     1201 caacgcgttc cgtggatacc ccggttatcg gcctgaaaga gctgatggtg cagcatgaag
     1261 aacgcattcg taacgggatg aaggcgtact ctctgctcga acaactgcgt tctggttcta
     1321 ccgaccaggc ggttcgtgac cagttcaata gcatgaagaa agacctcggt tacggtctgc
     1381 tgctgaaacg ctatacgcca aacgtggctg atgcgactga agcgcagatt caacaggcaa
     1441 ccaaagactc catcccgcgt gtagcgccgc tgtactttgc gttccgtatc atggtggcgt
     1501 gtggcttcct gcttctggca atcatcgcgc tctctttctg gagtgtcatc cgcaaccgca
     1561 ttggcgagaa aaaatggctt ctgcgcgccg cgctgtacgg tattccgctg ccgtggattg
     1621 ctgtagaagc gggctggttc gtggctgaat atggccgcca accgtgggct atcggtgaag
     1681 tgctgccgac agctgtggcg aactcgtcac tgaccgcagg cgatctcatc ttctcaatgg
     1741 tgctgatttg cggcctgtat accctgttcc tggtggcaga attgttctta atgttcaaat
     1801 ttgcacgcct cggcccaagc agcctgaaaa ccggtcgcta tcactttgag cagtcttcca
     1861 cgactactca gccggcacgc taagacagga gtcgtcaaat gatcgattat gaagtattgc
     1921 gttttatctg gtggctgctg gttggcgttc tgctgattgg ttttgcagtc actgacggtt
     1981 tcgacatggg ggtgggcatg ctcacccgtt tcctcggtcg taacgacacc gagcgtcgaa
     2041 ttatgattaa ctccattgca ccacactggg acggtaacca ggtttggctg atcaccgcgg
     2101 gcggcgcact ctttgctgcc tggccgatgg tctatgccgc tgcgttctcc ggcttctatg
     2161 tggcgatgat cctcgtgctg gcgtctttgt tcttccgtcc ggtcggtttt gactaccgct
     2221 ccaagattga agaaacccgc tggcgtaaca tgtgggactg gggcatcttc attggtagct
     2281 tcgttccgcc gctggtaatt ggtgtagcgt tcggtaacct gttgcagggc gtaccgttca
     2341 acgttgatga atatctgcgt ctgtactaca ccggtaactt cttccagttg cttaacccgt
     2401 tcggcctgct ggcaggcgtg gtgagcgtag ggatgatcat tactcagggc gcaacctatc
     2461 tgcaaatgcg taccgtgggc gaactgcacc tgcgtacccg tgcaacggct caggtggctg
     2521 cgctggtgac actggtctgt ttcgcactgg ctggcgtatg ggtgatgtac ggtatcgatg
     2581 gttatgtcgt gaaatcgaca atggaccatt acgcagcctc taacccactg aataaagaag
     2641 tggttcgtga agctggcgca tggctggtta acttcaacaa cacgccaatt ctgtgggcta
     2701 ttccggcact gggtgtggtt ctgccgctgc tgaccatcct gactgcacgt atggataaag
     2761 ccgcgtgggc gtttgtgttc tcctccctga cgctggcctg catcatcctg acagccggta
     2821 tcgcaatgtt cccgtttgtg atgccgtcca gcaccatgat gaacgcaagt ctgacaatgt
     2881 gggatgcaac ttccagccag ctgacgctta acgtcatgac ctgggttgcg gtggttctgg
     2941 taccgatcat tctgctctac accgcctggt gttactggaa aatgttcggt cgtatcacca
     3001 aagaagatat tgaacgtaac acccactctc tgtactaagt aaggagctaa aaatgtggta
     3061 tttcgcatgg attctgggaa cgcttcttgc ctgttcgttt ggggtaatca ccgcgctggc
     3121 gcttgaacac gtcgaatcag gcaaagccgg tcaagaagac atctgatgag taagattatc
     3181 gcgactttgt atgcggtaat ggacaagcgc cccctgcggg cgctttcctt cgtgatggcg
     3241 cttctgttag caggatgtat gttttgggac ccatctcgtt ttgccgcgaa gaccagtgaa
     3301 ctggaaatct ggcatggttt attgctgatg tgggccgtct gtgctggtgt gattcacggc
     3361 gtgggctttc gtccgcagaa ggttctttgg caagggattt tttgcccatt gcttgccgat
     3421 attgttctca ttgtcgggct gattttcttc ttcttttaaa tcagaattct ctttaaaaaa
     3481 ttatgggccg ctccaggccc ataaattttt acgctccctt aacttgccct cattcccaaa
     3541 cctcaatcgc gcgcgtatag tagcagcgtt taaaagctct aacttttgtt gcattaccgg
     3601 gatgtaaagt gaatacaacg ctgtttcgat ggccggttcg cgtctactat gaagataccg
     3661 atgccggtgg tgtggtgtac cacgccagtt acgtcgcttt ttatgaaaga gcacgcacag
     3721 agatgctgcg tcatcatcac ttcagtcagc aggcgctgat ggctgaacgc gttgcctttg
     3781 tggtacgtaa aatgacggtg gaatattacg cacctgcgcg gctcgacgat atgctcgaaa
     3841 tacagactga aataacatca atgcgtggca cctctttggt tttcacgcaa cgtattgtca
     3901 acgccgagaa tactttgctg aatgaagcag aggttctggt tgtttgcgtt gacccactca
     3961 aaatgaagcc tcgtgcgctt cccaagtcta ttgtcgcgga gtttaagcag tgactgacat
     4021 gaatatcctt gatttgttcc tgaaggctag ccttctggtt aaacttatca tgttgatttt
     4081 gattggtttt tcaatcgcat cttgggccat tattatccag cggacccgta ttcttaacgc
     4141 agcggcgcgc gaagccgaag cgtttgaaga taaattctgg tctggaatcg aactctctcg
     4201 cctctatcaa gagagccagg ggaaacggga taatctgact ggttcggaac aaatctttta
     4261 cagcgggttc aaagagtttg tgcgcctgca tcgtgccaat agccatgcgc cggaagccgt
     4321 agtggaaggg gcgtcgcgtg ctatgcgtat ctccatgaac cgtgaacttg aaaatctgga
     4381 aacgcacatt ccgttcctcg gtacggttgg ctccatcagc ccgtatattg gtctgtttgg
     4441 tacggtctgg gggatcatgc acgcctttat cgccctcggg gcggtaaaac aagcaacact
     4501 gcaaatggtt gcgcccggta tcgcagaagc gttgattgcg actgcaattg gtctgttcgc
     4561 cgcaattccg gcggtaatgg cttataaccg cctcaaccag cgcgtaaaca aactggaact
     4621 gaattacgac aactttatgg aagagtttac cgcgattctg caccgccagg cgtttaccgt
     4681 tagcgagagc aacaaggggt aagccatggc cagagcgcgt ggacgaggtc gtcgcgatct
     4741 caagtccgaa atcaacattg taccgttgct ggacgtactg ctggtgctgt tgctgatctt
     4801 tatggcgaca gcgcccatca tcacccagag cgtggaggtc gatctgccag acgctactga
     4861 atcacaggcg gtgagcagta acgataatcc gccagtgatt gttgaagtgt ctggtattgg
     4921 tcagtacacc gtggtggttg agaaagatcg cctggagcgt ttaccaccag agcaggtggt
     4981 ggcggaagtg tccagccgtt tcaaggccaa cccgaaaacg gtctttctga tcggtggcgc
     5041 aaaagatgtg ccttacgatg aaataattaa agcactgaac ttgttacata gtgcgggtgt
     5101 gaaatcggtt ggtttaatga cgcagcctat ctaaacatct gcgtttccct tgcttgaaag
     5161 agagcgggta acaggcgaac agtttttgga aaccgagagt gtcaaaggca accgaacaaa
     5221 acgacaagct caagcgggcg ataattattt cagcagtgct gcatgtcatc ttatttgcgg
     5281 cgctgatctg gagttcgttc gatgagaata tagaagcttc agccggaggc ggcggtggtt
     5341 cgtccatcga cgctgtcatg gttgattcag gtgcggtagt tgagcagtac aaacgcatgc
     5401 aaagccagga atcaagcgcg aagcgttctg atgaacagcg caagatgaag gaacagcagg
     5461 ctgctgaaga actgcgtgag aaacaagcgg ctgaacagga acgcctgaag caacttgaga
     5521 aagagcggtt agcggctcag gagcagaaaa agcaggctga agaagccgca aaacaggccg
     5581 agttaaagca gaagcaagct gaagaggcgg cagcgaaagc ggcggcagat gctaaagcga
     5641 aggccgaagc agatgctaaa gctgcggaag aagcagcgaa gaaagcggct gcagacgcaa
     5701 agaaaaaagc agaagcagaa gccgccaaag ccgcagccga agcgcagaaa aaagccgagg
     5761 cagccgctgc ggcactgaag aagaaagcgg aagcggcaga agcagctgca gctgaagcaa
     5821 gaaagaaagc ggcaactgaa gctgctgaaa aagccaaagc agaagctgag aagaaagcgg
     5881 ctgctgaaaa ggctgcagct gataagaaag cggcagcaga gaaagctgca gccgacaaaa
     5941 aagcagcaga aaaagcggct gctgaaaagg cagcagctga taagaaagca gcggcagaaa
     6001 aagccgccgc agacaaaaaa gcggcagcgg caaaagctgc agctgaaaaa gccgctgcag
     6061 caaaagcggc cgcagaggca gatgatattt tcggtgagct aagctctggt aagaatgcac
     6121 cgaaaacggg gggaggggcg aaagggaaca atgcttcgcc tgccgggagt ggtaatacta
     6181 aaaacaatgg cgcatcaggg gccgatatca ataactatgc cgggcagatt aaatctgcta
     6241 tcgaaagtaa gttctatgac gcatcgtcct atgcaggcaa aacctgtacg ctgcgcataa
     6301 aactggcacc cgatggtatg ttactggata tcaaacctga aggtggcgat cccgcacttt
     6361 gtcaggctgc gttggcagca gctaaacttg cgaagatccc gaaaccacca agccaggcag
     6421 tatatgaagt gttcaaaaac gcgccattgg acttcaaacc gtaatcgcga tgttgactgt
     6481 tcggacggtc aacatcaggc accggttgcc acggggttct ggtagttttg tgtattttag
     6541 tttgttaaca ttctgctaaa ttatcgtggg ccatcggtcc agataaggga gatatgatga
     6601 agcaggcatt acgagtagca tttggttttc tcatactgtg ggcatcagtt ctgcatgctg
     6661 aagtccgcat tgtgatcgac agcggtgtag attccggtcg tcctattggt gttgttcctt
     6721 tccagtgggc ggggcctggt gcggcacctg aagatattgg cggcatcgtt gctgctgact
     6781 tgcgtaacag cggtaaattt aatccgttag atcgcgctcg tctgccacag cagccgggta
     6841 gtgcgcagga agtacaacca gctgcatggt ccgcactggg cattgacgct gtagttgtcg
     6901 gtcaggtcac tccgaatccg gatggttctt acaatgttgc ttatcaactt gttgacactg
     6961 gcggcgcacc gggtactgta cttgctcaga actcgtacaa agtgaacaag cagtggctgc
     7021 gttatgctgg tcataccgcc agtgatgaag tgtttgaaaa actgaccggc attaaaggtg
     7081 cgttccgtac tcgtattgcc tacgttgttc agaccaacgg cggtcagttc ccgtatgaac
     7141 tgcgcgtatc tgactatgac ggttacaacc agtttgtcgt tcaccgttca ccgcagccgc
     7201 tgatgtctcc ggcgtggtca ccagacggtt ctaaactggc ttatgtgacc ttcgaaagcg
     7261 gtcgttccgc gctggttatt cagacgctgg caaatggcgc tgtacgtcag gtggcttcat
     7321 tcccgcgtca caacggtgca cctgcattct cgccagacgg cagcaaactg gcattcgcct
     7381 tgtcgaaaac cggtagtctg aacctgtacg taatggattt ggcttctggt cagatccgcc
     7441 aggtgactga tggtcgcagt aacaataccg aaccgacctg gttcccggat agccagaacc
     7501 tggcatttac ttctgaccag gccggtcgtc cgcaggttta taaagtgaat atcaacggcg
     7561 gtgcgccaca acgtattacc tgggaaggtt cgcagaacca ggatgcggat gtcagcagcg
     7621 acggtaaatt tatggtaatg gtcagctcca atggtgggca gcagcacatt gccaaacaag
     7681 atctggcaac gggaggcgta caagttctgt cgtccacgtt cctggatgaa acgccaagtc
     7741 tggcacctaa cggcactatg gtaatctaca gctcttctca ggggatggga tccgtgctga
     7801 atttggtttc tacagatggg cgtttcaaag cgcgtcttcc ggcaactgat ggacaggtca
     7861 aattccctgc ctggtcgccg tatctgtgat aataattaat tgaatagtaa aggaatcatt
     7921 gaaatgcaac tgaacaaagt gctgaaaggg ctgatgattg ctctgcctgt tatggcaatt
     7981 gcggcatgtt cttccaacaa gaacgccagc aatgacggca gcgaaggcat gctgggtgcc
     8041 ggcactggta tggatgcgaa cggcggcaac ggcaacatgt cttccgaaga gcaggctcgt
     8101 ctgcaaatgc aacagctgca gcagaacaac atcgtttact tcgatctgga caagtacgat
     8161 atccgttctg acttcgctca aatgctggat gcacatgcaa acttcctgcg tagcaacccg
     8221 tcttacaaag tcaccgtaga aggtcacgcg gacgaacgtg gtactccgga atacaacatc
     8281 tccctgggtg aacgtcgtgc gaacgccgtt aagatgtacc tgcagggtaa aggcgtttct
     8341 gcagaccaga tctccatcgt ttcttacggt aaagaaaaac ctgcagtact gggtcatgac
     8401 gaagcggcat actccaaaaa ccgtcgtgcg gtactggttt actaagagaa ttgcatgagc
     8461 agtaacttca gacatcaact attgagtctg tcgttactgg ttggtatagc ggccccctgg
     8521 gccgcttttg ctcaggcacc aatcagtagt gtcggctcag gctcggtcga agaccgcgtc
     8581 actcaacttg agcgtatttc taatgctcac agccagcttt taacccaact ccagcaacaa
     8641 ctttctgata atcaatccga tattgattcc ctgcgtggtc agattcagga aaatcagtat
     8701 caactgaatc aggtcgtgga gcggcaaaag cagatcctgt tgcagatcga cagcctcagc
     8761 agcggtggtg cagcggcgca atcaaccagc agcgatcaaa gcggtgcggc ggcatcaacg
     8821 acgccgacag ctgatgctgg tactgcgaat gctggcgcgc cggtgaaaag cggcgatgca
     8881 aacacggatt acaatgcagc tattgcgctg gtgcaggata aatcccgcca ggatgacgca
     8941 atggtggcat ttcagaattt catcaaaaat taccctgatt caacttacct gccaaacgcc
     9001 aattattggc tgggtcagtt aaactacaac aagggtaaaa aagatgatgc ggcgtactat
     9061 tttgcttcgg tagtgaaaaa ctatccgaag tcaccaaagg ctgctgatgc gatgtttaaa
     9121 gtcggcgtca tcatgcagga caaaggtgac accgcaaaag cgaaagccgt ataccagcag
     9181 gttatcagta aataccctgg tactgatggc gctaaacagg cacaaaaacg tctgaacgcg
     9241 atgtaatgca taacacacga ccagaagtcg cattatttct ggtcgtgtcg tgcgaatcat
     9301 aagcagttga gtgatctgca tcgaaatttt tgttgcgctc aagtctgaaa tcagtaatat
     9361 atgccgccgt tgccacggga tatcaaacaa accgaaagca acgaaaaagt gggtcgttag
     9421 ctcagttggt agagcagttg acttttaatc aattggtcgc aggttcgaat cctgcacgac
     9481 ccaccaatcg ctaaggtgga agcggtagta aaacgtgaag gataacgttg catcagcaac
     9541 ggcccgaagg gcgagacgaa gtcgagtcat cctgcacgac ccaccactaa catagttagt
     9601 tgtagtatcc agcgtagtat tgggtgatta gctcagctgg gagagcacct cccttacaag
     9661 gagggggtcg gcggttcgat cccgtcatca cccaccaccg ggtcgttagc tcagttggta
     9721 gagcagttga cttttaatca attggtcgca ggttcgaatc ctgcacgacc caccagtttt
     9781 agcatcgaag acagatgtta agcgtgtagg ataacgttgc gtcagcaacg gcccgtaggg
     9841 cgagcgaagc gagtcatcct gcacgaccca ccactaatta cggtgggttc ggtggaagta
     9901 gtttgtagta tccagcgcag tatcgggtga ttagctcagc tgggagagca cctcccttac
     9961 aaggaggggg tcggcggttc gatcccgtca tcacccacca ctcgggtcgt tagctcagtt
    10021 ggtagagcag ttgactttta atcaattggt cgcaggttcg aatcctgcac gacccaccaa
    10081 ttttaacatc aaactcagat gttaagcgtg aaggataacg ttgcgccagc aacggcccgt
    10141 agggcaagcg aagcgagtca tcctgcacga cacaccaatc ttaaagattg gccccgagta
    10201 gaaatctttc aggtaacacc cgtatgggtc gttagctcag ttggtagagc agttgacttt
    10261 taatcaattg gtcgcaggtt cgaatcctgc acgacccacc atcctgaatg attaaagcag
    10321 cataatcccg caaggggtcg ttagctcagt tggtagagca gttgactttt aatcaattgg
    10381 tcgcaggttc gaatcctgca cgacccacca atgtaaaaaa gcgccctaaa ggcgcttttt
    10441 tgctattcag gcatcctcaa tttcactttg taaacctgat gacatcgtca gagcttactg
    10501 tgcaagcaac tctacgtcgg tggaattagg cgtaattcga gtgacttttc cccaccattc
    10561 gactatcttg tttagcatat aaaacaaatt acaccgataa cagcgaatat tacgctaatg
    10621 tcggttttaa cgttaagcct gtaaaacgag atggtaagat gagcgtaatg tttgatccag
    10681 acacggcgat ttatcctttc cccccgaagc cgacgccgtt aagcattgat gaaaaagcgt
    10741 attaccgcga gaagataaaa cgtctgctaa aagaacgtaa tgcggtgatg gttgcccact
    10801 actataccga tcccgaaatt caacaactgg cagaagaaac cggtggctgt atttctgatt
    10861 ctctggaaat ggcgcgcttc ggtgcaaagc atcccgcttc tactttgtta gtcgctgggg
    10921 tgagatttat gggagaaacc gccaaaattc tcagtccgga aaaaacaatt ctgatgccga
    10981 cacttcaggc tgaatgttca ctggatctcg gctgccctgt tgaagaattt aacgcatttt
    11041 gcgatgccca tcccgatcgt actgtcgtcg tctacgccaa cacttctgct gcggtaaaag
    11101 cgcgcgcaga ttgggtggta acttcaagca ttgccgtcga acttattgat catcttgata
    11161 gtttgggtga aaaaatcatc tgggcacccg acaaacatct ggggcgttac gtgcaaaaac
    11221 agacgggtgg agacattcta tgctggcagg gtgcctgtat tgtgcatgat gaatttaaga
    11281 ctcaggcgtt aacccgcttg caagaagaat acccggatgc tgccatactg gtgcatccag
    11341 aatcaccaca agctattgtc gatatggcgg atgcggtcgg ttccaccagt caactgatcg
    11401 ctgctgcgaa aacattgcca catcagcggc ttatcgtggc aaccgatcgg ggcattttct
    11461 acaaaatgca gcaggcagtg ccagataaag agttactgga agcaccaacc gcaggtgagg
    11521 gtgcaacctg ccgcagctgc gcgcattgtc cgtggatggc catgaatggc cttcagtcca
    11581 tcgcagaggc attagaacag gaaggaagca atcacgaggt tcatgttgat gaaaggctgc
    11641 gagagagggc gctggtgccg ctcaatcgta tgctggattt tgcggctaca ctacgtggat
    11701 aacgaataat aaggcgtaac gttacgcttt gggggaaaga tggatttttt tagtgtgcag
    11761 aatatcctgg tacatatacc aataggggca ggcggttatg atctctcatg gatcgaagcg
    11821 gtaggcacga tcgccgggtt gctgtgtatt ggccttgcca gtctggagaa gatcagcaac
    11881 tacttctttg gcctgatcaa cgtcaccttg tttggcatta ttttctttca gattcagctg
    11941 tatgccagcc tgctattaca ggtgtttttc tttgccgcga atatttacgg ttggtatgcg
    12001 tggtcgcgac aaaccagtca gaacgaggcg gagttgaaaa ttcgctggtt gccattgccg
    12061 aaggcactca gctggttggc ggtttgcgtt gtttcgattg gtctgatgac ggtatttatc
    12121 aatccggtgt ttgcattttt gacccgcgtg gcagtcatga tcatgcaagc attaggatta
    12181 caggttgtga tgcctgaact gcaaccggac gctttcccgt tctgggattc atgcatgatg
    12241 gtgttatcta tcgtggcaat gattctgatg acgcgtaagt atgtggaaaa ctggctgttg
    12301 tgggtgatta ttaacgtgat tagcgtcgtt atttttgcac ttcagggcgt ttacgccatg
    12361 tctctggagt acatcatcct gacctttatt gcgctcaacg gcagccggat gtggatcaac
    12421 agcgcacgtg aaagaggctc acgcgcgctg tcccattaat ggtgatgatg tgaatggcca
    12481 gacacccctt cattcaggtg gcagtctggc ccatgacaag gttgatattc catctgaatg
    12541 gtggcgtgct caatctgata gtgatccatc aggtagtgtt ggatctgatc caacaaggca
    12601 tcgtgatcgt gtggcgggat cacctgcaca tgcaacgtca tcaccggctt ctcgcctacc
    12661 atccatacat gtacatggtg cacattgcgg acttccggga tttcccggca catacgacgc
    12721 ttcagttcag cgatatccag cgataccggt gcaccttcaa gtaattcatt cacgctatct
    12781 ttcaacagtc gccacgcgct acgcagaacc agaagcgaca ccagtatcga gagaatgggg
    12841 tcagcaggtg tccagccagt ccagataata atcaacgcgg caataatagc cccaaccgaa
    12901 cccagcaggt ccccgagcac atgcagtgcc gctgctcgta cgttgaggtt tttctcttcg
    12961 ctgccgtgat gaagtaacca gaaagaaagt atatttgcca gcaacccagc cacggcaatt
    13021 gccatcatca tgccgccctc gaccggacgc ggcgtgcgga agcgttctat cgcctcccag
    13081 acaatcaaaa tggtaattac cacgagggct atggcattca caaacgccgc gagcgtggtc
    13141 agtcttagcc aaccgaaagt gtggcgaatg gtgggaggac gacgtgaaaa ttgcacggcg
    13201 agtagggcga aaagcagggc ggcagtatcg gtcaacatat gacccgcatc ggccagcaat
    13261 gccagagaac cagaaagaaa accaccaacg acttctacca gcataaaccc ggcagtcacg
    13321 ccgaaagcat acaacaagcg acgagcatta ttatcttctg gcaggtgtga ggacgtgtgt
    13381 gagtgtgagt gcgccatgac gagtcatccc ttaattattc tcacttaact ttatgacatc
    13441 atactgcttt tagaagtgaa aaattaaaag ggagagactc cgctctccca ttattggcta
    13501 ttttgcaggg ttactgcgtg gtaccgtcgg ttttggtatc gacatcatta ttgatgccat
    13561 caccggtttg taccttttta ttgatatccg gacagcgacc atctttgcac atggtgttct
    13621 tgtgctcttc atctttggtc attccgtcat tgttcattga agaaccatcc gaatgcagca
    13681 ttgtgccacc agaaccggta tttaccccgt tattgtcgac gttatttggc gcgacatttt
    13741 cacgggcgtc aggggctacc tggcccgcat cagctgcggc gtttgcctgg ccgttattag
    13801 tttgcgctcc gctatcggca gccagtgcgg caccgctggc aaggcttaga gtggcagtca
    13861 gaaataatgt ggccagtttt gtcattttca taggatgctc ctgttatggt cgttatgtcg
    13921 gataacctct tccaacagtg catttgcagg tgaatataag gcattggttt aagatttcag
    13981 ccaggttatg aaacgcagca gagaatcttg aaataattaa caaacaaagg agttacagtt
    14041 agaaattgta ggagagatct cgtttttctc gacaatctgg cgtttttctt gctaattcca
    14101 ggattaatcc gttcatagtg taaaaccccg tttacacatt ctgacggaag atatagattg
    14161 gaagtattgc attcactaag ataagtatgg caacactgga acagacatga attatcagaa
    14221 cgacgattta cgcatcaaag aaatcaaaga gttacttcct cctgtcgcat tgctggaaaa
    14281 attccccgct actgaaaatg ccgcgaatac ggttgcccat gcccgaaaag cgatccataa
    14341 gatcctgaaa ggtaatgatg atcgcctgtt ggttgtgatt ggcccatgct caattcatga
    14401 tcctgtcgcg gcaaaagagt atgccactcg cttgctggcg ctgcgtgaag agctgaaaga
    14461 tgagctggaa atcgtaatgc gcgtctattt tgaaaagccg cgtaccacgg tgggctggaa
    14521 agggctgatt aacgatccgc atatggataa tagcttccag atcaacgacg gtctgcgtat
    14581 agcccgtaaa ttgctgcttg atattaacga cagcggtctg ccagcggcag gtgagtttct
    14641 cgatatgatc accccacaat atctcgctga cctgatgagc tggggcgcaa ttggcgcacg
    14701 taccaccgaa tcgcaggtgc accgcgaact ggcatcaggg ctttcttgtc cggtcggctt
    14761 caaaaatggc accgacggta cgattaaagt ggctatcgat gccattaatg ccgccggtgc
    14821 gccgcactgc ttcctgtccg taacgaaatg ggggcattcg gcgattgtga ataccagcgg
    14881 taacggcgat tgccatatca ttctgcgcgg cggtaaagag cctaactaca gcgcgaagca
    14941 cgttgctgaa gtgaaagaag ggctgaacaa agcaggcctg ccagcacagg tgatgatcga
    15001 tttcagccat gctaactcgt ccaaacaatt caaaaagcag atggatgttt gtgctgacgt
    15061 ttgccagcag attgccggtg gcgaaaaggc cattattggc gtgatggtgg aaagccatct
    15121 ggtggaaggc aatcagagcc tcgagagcgg ggagccgctg gcctacggta agagcatcac
    15181 cgatgcctgc atcggctggg aagataccga tgctctgtta cgtcaactgg cgaatgcagt
    15241 aaaagcgcgt cgcgggtaag gtttaattgt cggatgcgcc gtcagagtgg cgtatccgat
    15301 gaatcaccac aggcctgata agtcgcgcag cgtcgcatca ggcaatgtgc tccattgtta
    15361 gcaacaaaaa tgccgactca cttgcagtcg gctttctcat tttaaacgaa tgacgtttac
    15421 ttcgctttac cctggtttgc aaccgccgct gctttcgctg cgatctcgtc agcattaccc
    15481 agataatagc gtttcagcgg tttgaaattc tcgtcgaact catacaccag cggcacgcca
    15541 gtcgggatat taagctcaag aatctcttct tcgctcatgt tatcaagata tttcaccagc
    15601 gcacgtaaag agttaccgtg tgcagcgatg atcacgcgct caccgctctt catacgcggc
    15661 agaatagttt cattccagta agggatcacg cggtcaatgg tcagcgccag gctttccgtc
    15721 agcggcagtt ctttttcgct cagtttcgcg taacgcggat cgtgacccgg ataacgctca
    15781 tcatctttag tcagttccgg cggagtcact gcaaaaccac gacgccactg tttcacctgc
    15841 tcgtcgccat acttttcagc agtttccgct ttgttcagac cctgcaacgc accgtagtga
    15901 cgttcgttca gtttccagga tttctcaacg ggcagccatg cctgatccag ttcgtccagc
    15961 acattccaca gggtatggat agcgcgtttc agcacagagg tgtaagcaaa gtcaaagctg
    16021 taaccttcct ctttcagcag cttacctgct gcttttgctt cgcttacgcc tttctcagac
    16081 agatccacgt cgtaccaacc ggtgaaacgg ttttctttgt tccactgact ttcgccatga
    16141 cgaaccagaa ccagcttagt tacagccata tacttactcc tcaaatcatt ttttaatgat
    16201 aataattctc attatattgc cgtgacgaag caacagcaat gcttacgcat aaccatagcg
    16261 aaaatagtgt cgcagtgtaa ggttgttgtg aatattgagt tgcaaatatg tcggtgtttg
    16321 ctggtgattt gagcaatata aggataaagc cctcattacg agggcttcag gtgctactca
    16381 gcaataaact gatattccgt caggctggaa tactcttcgc caggacgcag gaagcagtcc
    16441 ggttgcggcc attcagggtg gtttgggctg tccggcagaa actcgctttc cagtgccagg
    16501 ccttgccagt cggcgtaagg ttcagttcct cttgatggcg tgccgccgag gaagttgccg
    16561 gagtagaatt gcagagccgg agcggtggtg tagaccttca gctgcaattt ttcatctgct
    16621 gaccagacat gcgccgccac tttcttgcca tcgcctttgg cctgtaacaa gaatgcgtga
    16681 tcgtaacctt tcactttgcg ctgatcgtcg tcggcaagaa actcactggc gatgattttg
    16741 gcgctacgga aatcaaaaga cgttccggcg acagatttca ggccgtcgtg cggaatgccg
    16801 ccttcatcaa ccggcagata ttcgtccgcc agaatctgca acttgtgatt gcgcacgtca
    16861 gactgctcgc cgtcaagatt gaaatagacg tgattagtca tattcaccgg gcaaggttta
    16921 tcaactgtgg cgcgataagt aatagagata cggttatcgt cggtcagacg atattgcacc
    16981 gtcgcgccga gattacccgg gaagccctga tcgccatcat ctgaactcag ggcaaacagc
    17041 acctgacgat cgttctggtt cacaatctgc cagcgacgtt tgtcgaaccc ttccgggccg
    17101 ccgtgcagct ggttaacgcc ctgacttggc gaaagcgtca cggtttcacc gtcaaaggta
    17161 taacggctat tggcgatgcg gttggcataa cgaccaatag aggcccccag aaacgcagcc
    17221 tgatcctgat agcattccgg gctggcacag ccgagcagcg cctcgcggac gctgccatcg
    17281 gaaagcggaa tacgggcgga aagtaaagtc gcaccccagt ccatcagcgt gactaccatc
    17341 cctgcgttgt tacgcaaagt taacagtcgg tacggctgac catcgggtgc cagtgcggga
    17401 gtttcgttca gcactgtcct gctccttgtg atggtttaca aacgtaaaaa gtctctttaa
    17461 tacctgtttt tgcttcatat tgttcagcga cagcttgctg tacggcaggc accagttctt
    17521 ccgggatcaa cgcgacgata cagccaccaa atccgccgcc ggtcatgcgt acgccacctt
    17581 tgtcaccaat cacagctttg acgatttcta ccagagtgtc aatttgcggc acggtgattt
    17641 cgaaatcatc gcgcatagag gcatgagact ccgccattaa ctcgcccata cgtttcaggt
    17701 cgccttgctc cagcgcgctg gcagcttcaa cggtgcgggc gttttcggtc aggatatgac
    17761 gcacgcgttt cgccacgatc gggtccagtt catgcgcaac agcgttgaac tcttcaatgg
    17821 tgacatcgcg cagagctggc tgctggaaga aacgcgcacc ggtttcgcac tgctcacggc
    17881 gagtattgta ctcactgcca accagggtac gtttgaagtt actgttgatg atgaccacag
    17941 ctacgccttt cggcatggaa actgctttgg tccccagtga gcggcagtca atcagcaagg
    18001 catgatcttt cttgccgagc gcggaaatta gctgatccat gatcccgcag ttacagccaa
    18061 caaactggtt ttctgcttcc tgaccattaa gcgcgatttg tgcgccgtcc agcggcagat
    18121 gataaagctg ctgcaatacg gttccgaccg cgacttccag tgaagcggaa gaacttaacc
    18181 cggccccctg cggcacattg ccgctgatca ccatgtccac accgccgaag ctgttgttac
    18241 gcagttgcag atgtttcacc acgccacgaa cgtagttcgc ccattgatag ttttcatgcg
    18301 cgacaatggg cgcatcgagg gaaaactcgt cgagctgatt ttcataatcg gctgccatta
    18361 cgcgaacttt acggtcatcg cgtggcgcac agctgatcac ggtttgataa tcaatcgcgc
    18421 agggcagaac gaaaccgtcg ttgtagtcgg tgtgttcacc aatcaaattc acgcggccag
    18481 gcgcctgaat ggtgtgagtg gcagggtagc caaatgcgtt ggcaaacaga gattgtgttt
    18541 tttctttcag actcatttct tacactccgg attcgcgaaa atggatatcg ctgactgcgc
    18601 gcaaacgctc tgctgcctgt tctgcggtca ggtctcgctg ggtctctgcc agcatttcat
    18661 aaccaaccat aaatttacgt acggtggcgg agcgcaacag aggcggataa aagtgcgcgt
    18721 gcagctgcca gtgttgattc tcttcgccat taaatggcgc gccgtgccag cccatagagt
    18781 aggggaagga gcactggaag aggttgtcat aacgactggt cagctttttc aacgccagtg
    18841 ctaaatcgct gcgctgggca tcggtcaaat cggtgatccg taaaacgtgg gctttgggca
    18901 gcagtagcgt ttcgaacggc caggcagccc agtaaggcac tacggctaac cagtgttcgg
    18961 tttcgacaac ggtacggcta ccgtctgcca gctcgcgctg aacataatcc accagcattg
    19021 gcgatttctg cccggcaaaa tattcttttt gcaggcggtc ttcgcgctca gcttcgttag
    19081 gcaggaagct atttgcccaa acctgtccgt gcggatgcgg gttagagcag cccatcgccg
    19141 cacctttgtt ttcaaagacc tgcacccacg ggtacgtttt tcccagctct gcggtttgct
    19201 cctgccaggt tttgacgatt tccgtcaatg ccgcaacgct cagttctggc aacgttttac
    19261 tgtgatccgg tgaaaagcag atcacccggc tggtaccgcg cgcgctctgg caacgcatca
    19321 aaggatcgtt gctttctggc gcatctggcg tgtcagacat caaggccgca aaatcattag
    19381 tgaaaacgta agtcccggtg taatcggggt ttttatcgcc tgtcacccgc acattacctg
    19441 cgcagaggaa gcaatctgga tcgtgcgcag gtaacacctg tttggctggc gtttcctgcg
    19501 ccccctgcca ggggcgctta gcgcggtgcg gtgaaaccag aatccattgc ccggtgagcg
    19561 ggttgtagcg gcgatgtgga tgatcaacgg gattaaattg cgtcatggtc gttccttaat
    19621 cgggatatcc ctgtggatgg cgtgactgcc agtgccaggt gtcctgcgcc atttcatcga
    19681 gtgtgcgcgt tacgcgccag ttcagttcgc gatcggcttt gctggcgtcc gcccagtagg
    19741 ccggaaggtc gccctcgcga cgcggtgcaa aatgatagtt aaccggtttg ccgcaggctt
    19801 tgctgaaggc attaaccacg tccagcacgc tgctgcctac gccagcgccg aggttgtaga
    19861 tgtgtacgcc tggcttgttc gccagttttt ccatcgccac gacgtgaccg tccgccagat
    19921 ccattacgtg gatgtaatcg cgtacgccag taccatcttc ggtcggataa tcgttaccaa
    19981 aaatcgccag cgagtcgcga cggcctacag caacctgggc gatgtatggc atcaggttat
    20041 tcggaatgcc ttgcggatct tcacccatat cgcccgacgg atgcgcgcca accgggttga
    20101 agtagcgcag cagggcaatg ctccagtccg gctgggcttt ttgcaggtcg gtgaggatct
    20161 gttccaccat caatttgctt ttgccataag ggctttgcgg tgtgccggtc gggaagcttt
    20221 caacgtatgg aattttgggc tgatcgccat aaacggtggc ggaggagcta aaaataaagt
    20281 ttttgacgtt agcggcgcgc atggcgctaa tcaggcgcag agtgccgttg acattgttgt
    20341 cgtaatattc cagcggtttt tgtaccgatt cgccaacggc tttcagcccg gcgaagtgga
    20401 tcacggtgtc gatagcgtga tcgtgcagga tctcggtcat caacgcttcg ttacgaatat
    20461 cgccttcaac aaacgttgga tgtttgccgc ctaaacgctc gataacaggc agtacgctgc
    20521 gcttactgtt acagaggtta tcaagaatga tgacatcatg accgttttgc agtaattgca
    20581 cacaggtatg acttccaatg taaccgctac caccggtaac cagaactctc ataattcgct
    20641 ccattaggct tatggtatga aataaccata gcataacaaa gatgcgaaaa gtgtgacatg
    20701 gaataaatta gtggaatcgt ttacacaaga atttagccgt tttttatgcg cgattaagtg
    20761 attataaaac agagggttta tgaatgattg cgctttttat ctgaaaaaag acgcggtttc
    20821 atgcctgcat gcgtcgaact gtaggccgga gagggggctt acgccacatc cggcacagtc
    20881 agcattacca actcagttta tttttgtcag cgcatagcga taaaggtcac cgtccggcac
    20941 gaactcaaga cgatgggtaa tacaggcagg cgcatcttca gcgtggtgcg aaacaaacaa
    21001 caattgcgtt tcaccttcgc taatcagcac atcaacaaaa cggcggataa gttggcgatt
    21061 gagcggatca agcccctgta gtggttcatc gagaataagc aatgtcggat gtttcaccag
    21121 cgcgcggacg atcagcgcca gacgctgctg tccccaggaa agactatgga acggaacgtc
    21181 agccgtgcgt ttatcaatgc cgagaatatc cagccactgc tgcaccagtt tttgctggcg
    21241 atccgaaacg gcctgataaa tgccaatcga atcaaaatag ccagaaagaa tcacattacg
    21301 cacggtagtg ctgacccggt aatccagatg caaactactg ctgacgtaac cgatatgctt
    21361 tttgatatcc cagatggttt cgccgctgcc gcgacgtcgg ccgaaaagcg tcaaatcgtt
    21421 gctgtaacct tgcggatgat cgccagtaat caggcttaat aacgtcgatt ttcccgcacc
    21481 atttggcccg acaatttgcc agtgctcgcc aggattcacc tgccagctaa ggttattaag
    21541 aatggggcga tcgttataag aaaccacgcc attattcagc acaatgcgcg gttcgttggt
    21601 gggtaaggcg tgacgtgctg aaggttcatc cggctccggc agttgcacac cttcaagctg
    21661 ttcgctatgc gccagttgcg cgacgagtgc ttgctggagc agttcctctt tagcgcccgt
    21721 ttccgctaac gtacaatccg ccagcacgcc agcaaactgg acaaattccg ggatctcatc
    21781 gaagcgattg agcaccagta ccagagtaat accggactga tgtaacgagg cgagtcgctc
    21841 agccagctgc tgacgtgagg caacatccag gccatcgaac ggctcatcaa gaatcaacaa
    21901 gtcaggctcc gacatcagcg cctgacacag cagggttttt cgcgtctcgc cagtggaaag
    21961 gtatttaaag cgtcggtcga ggagggcggt aataccgaac tgctgcgcca gttgcatgca
    22021 acgcggtgca tccttaactt catcctgaat gatctcagcc gtagtgcgtc cggtgtcatc
    22081 ttcgccaggg ccgagcatat cggtgttatt ccgctgccat tcgtcgctga cgagcttttg
    22141 caattgctcg aaggagagac gagtgatgtg ggaaaactgg ctttgccgtt cacctttcaa
    22201 aagcggaagt tcccccgcca gcgcacgggc cagcgccgac tttccacttc cattcgaacc
    22261 gacaaacgcc caactatcac ccgcgtttaa cgttagctga ggcaattgca gcgtttttgt
    22321 gtcgctaaga cgaaacgtgc cttgcaaaat ttgcaacgat gacattttat atcccatttt
    22381 gtgcagcgat tactgatagg gatacgtgtt tcataacaaa ttgtcaacac gcttagcata
    22441 gcgtggcgat aatcacgctg tcggcattaa agtaggccgt gacattctgt ccttgctgaa
    22501 gagaagtcgc ttcattaacc ggcactgtgg cgcacagtgt ttgcccgtcg ggtagcgcca
    22561 ttaatacttc gcactgctct gcgccgcgct caatatgact aataataccc ggtaattggt
    22621 tgtcggcgtt ttgtgcgacc gcttcgtcct gagtaatgcc tacccacggc gcttttagca
    22681 atatcaacac ttctttgcct tcatccagcc ccagacgtgc gccgctttgt gcggtaattg
    22741 cgactttcag gcgtgttttt ccgtcagcca gtaagacatc aacatgctgt tgaacgtcat
    22801 catgatcgcg ggcggtgatg gtgccgaacc actggttacg ggcgctggtt tgcagtgaaa
    22861 aacgtgagat cgcggccagc aggctgttca gcggcagggc gtcatcgtca cttaacacat
    22921 caaaggcttt ttgctggatt tgcgccagta agtcatagag ctgaatcagt cgctgaccat
    22981 agcgggtcag tactgcgccg ccgccacctt taccgcctgt tgcgcgctcg accagaatat
    23041 gctcacttaa ctgattcatc tcgttaatgg catcccaggc gcttttatag ctgataccgg
    23101 catctttcgc tccctggcta atggaaccgg aaagcgcaat gtgttttagt agcgaaatgc
    23161 ggcgcgggtc ggcgaataat ttttgttgga gcttaagggt gagaaggatt tcggcctgca
    23221 taacaatgtc ctggcaaaag tcttattgtg acggaaaacg aacgccacgc aaagctgacc
    23281 gcacaaaagg ggagtgcttt tctgtgctta gcggttagaa tagtctcatg actatatctg
    23341 gagttgacca tgttagagtt attaaaaagt ctggtattcg ccgtaatcat ggtacctgtc
    23401 gtgatggcca tcatcctggg tctgatttac ggtcttggtg aagtattcaa catcttttct
    23461 ggtgttggta aaaaagacca gcccggacaa aatcattgat tccctgaatg cccgcttagt
    23521 cgggcatttt ctttttctca acttcctgct tttcctgccg atattttttc ttatctacct
    23581 cacaaaggtt agtaataact gctgggaaaa ttccgagtta gtcgttatat tgtcgcctac
    23641 ataacgttac attaaggggt taccaatggc tcgtaaatgg ttgaacttgt ttgccggggc
    23701 ggcactctct ttcgctgttg ctggcaatgc actggcagat gaagggaaaa tcacggtgtt
    23761 cgccgccgca tcactgacta acgcaatgca ggacattgct acgcagtata aaaaagagaa
    23821 aggcgtggat gtggtttctt ctttcgcttc gtcatctact ctcgcccgtc agattgaagc
    23881 gggtgcgcct gcggatctgt ttatttctgc cgatcagaaa tggatggatt atgcagttga
    23941 taaaaaagcg atcgatacag ctacgcgtca gacactgctc ggcaatagcc tggtcgttgt
    24001 agcaccgaaa gccagcgagc agaaagattt catcatcgac agcaaaacta actggacttc
    24061 gctgctgaat ggcggtcgcc tcgcggttgg cgatccggaa catgtccctg ctggcattta
    24121 tgcaaaagaa gcactgcaaa aactgggcgc atgggatacg ctctccccga aactggctcc
    24181 ggcggaagat gttcgtggcg cgctggcgtt ggtcgaacgc aatgaagcgc cgttgggcat
    24241 tgtttacggt tctgacgcag ttgccagcaa aggggtaaaa gtggttgcca ccttcccgga
    24301 agattcacat aaaaaagtgg aatatccggt tgctgttgtg gaagggcata acaatgcgac
    24361 agtgaaagca ttttatgatt atctgaaggg accgcaggct gcggaaatct ttaaacgtta
    24421 cggatttaca accaagtaat gatactgacc gatccagaat ggcaggcagt tttattaagc
    24481 ctgaaagttt cttccctggc tgtgctgttt agcctgccgt ttgggatctt ttttgcctgg
    24541 ttactggtgc gttgcacgtt tccgggcaaa gctttgctcg acagcatact gcatctaccg
    24601 ctggtgttac cgcccgtggt cgtcggttac ttattattag tttcgatggg acggcgcgga
    24661 tttatcggtg aacgtctgta tgactggttt ggtattacct tcgcctttag ctggcgcggc
    24721 gcggttctcg ctgccgccgt catgtcgttt ccgctaatgg tgcgggcaat tcgtctggcg
    24781 ctggaagggg ttgatgtcaa actggaacag gccgcaagaa cactgggggc cgggcgctgg
    24841 cgcgttttct ttactatcac gttaccgctg accttaccgg gaattattgt tggtacggta
    24901 ctggcttttg ctcgttctct cggtgaattt ggcgcaacca tcacctttgt gtcgaacatt
    24961 cctggtgaaa cgcgaaccat tccttctgcc atgtataccc tgattcagac ccccggcggg
    25021 gaaagtggcg cagcgagact gtgcattatt tctattgcgc tggcgatgat ctccctgttg
    25081 atttcagaat ggctggccag aatcagccgt gaacgggcgg ggcgctaatc atgctggaac
    25141 tgaatttttc ccagaccttg ggcaaccatt gcctgactat taatgaaacg ctgcccgcca
    25201 atggcatcac tgctatcttt ggcgtctccg gtgccggaaa aacttcgctg attaacgcca
    25261 tcagtggact gacgcgcccg caaaaaggga ggattgtcct caatggtcgg gtactaaatg
    25321 atgccgaaaa aggtatctgc ctgacgccag aaaaacgtcg cgttggctat gtttttcagg
    25381 atgcacggct gttcccgcat tacaaagtgc gtggcaattt gcgctacggc atggcgaaaa
    25441 gcatggtcga tcagttcgat aagctggtgg cgcttttagg cattgaaccg ttgcttgacc
    25501 gtttaccggg cagcctgtcc ggaggcgaaa aacagcgcgt ggcgattggt cgggctttgc
    25561 tgacggctcc ggaattgctg ttgctggatg aaccgctggc gtcactggat attccgcgta
    25621 aacgcgaact gttgccttat ctgcaacgtc tgacgcggga aatcaacatt ccgatgttgt
    25681 atgtcagcca ttcgctggat gagatcctcc atctggcaga cagagtgatg gtactggaaa
    25741 acggtcaggt gaaagccttt ggcgcgctgg aagaagtctg gggtagtagc gtgatgaatc
    25801 cgtggctgcc gaaagagcaa caaagtagca ttctgaaagt gacggtactt gagcatcatc
    25861 cgcattacgc gatgactgcg ctggcgctgg gcgatcagca tttgtgggtc aataagctgg
    25921 acgaaccgct gcaagctgcg ctacgtatcc gcattcaggc ttccgatgtt tctctggttt
    25981 tacaaccgcc gcagcaaacc agcattcgta acgtattgcg ggcaaaagtt gttaatagtt
    26041 atgacgacaa cggccaggtg gaagtggagc tggaagtcgg cggtaaaacg ctgtgggcgc
    26101 gtatcagccc gtgggccagg gatgaactgg cgatcaaacc tggcctgtgg ctgtacgcgc
    26161 aaattaaaag tgtgtcgata accgcctgat taaatcaggt ggctataaat gaactgggca
    26221 atgctgtcgg tggtgttatc accaatcaca atgttggcgc gcgcttttac cgcgtcatcg
    26281 gcgttgccca tcgccacgcc tgtaccagcg gcttccagca tactgatatc attaaagtta
    26341 tcgccgaatg ccacgacgtt ttccatcgac caaccttgcg cctcaaccca tttcgtcaaa
    26401 cgtttacctt tgctgttgcc gccgcgtgca atatcaacct gatcgtgcca ggaccattca
    26461 cactccagtc ccagttcatg ttcgacatgc ttaccaaaat gctgcaattg cggcaggtca
    26521 tcgtgcgtca gggcgaactt ccatacggcg ttaacttgtt gcgccgtttc agccagagaa
    26581 gcgacttgtg tgaaagtcgg acgctgttcc ggcggcaggg tttgcgccca gttagacgtg
    26641 cgaatgacat gcccggtcgg gtgctcatag accattgcat catcgacata catcagaccg
    26701 tgaatgtggt gttcattcag catctcaatg agttgcaggg ctttattaac gggcattggg
    26761 tccgcttcca gcacggtttt tgcatgataa tcatacaaat aggtgccatt acagcaaata
    26821 gcaggtgtat ccagcgccag cgcctgataa aaaggatgaa tagcgacgtg atggcgacct
    26881 gtgacgatga ttaattgata gcctgcttcg cgagcgcggg ccagggcttc tatcgatgaa
    26941 ggaagcaggg tctttttcgg ggtcaataag gtgccgtcta agtcgagagc aatcacgcgt
    27001 gtggtcatgg cgtattccag attaaggtta agaattttcg tctgcgcgaa tggtacaccg
    27061 ataccactat cggacaaaat tctgcgtttt aattcagcat tcaccgccaa aagcgactaa
    27121 ttttagctgt tacagtcagt tgctaaatgc aaaggagcat tcatgaagca aacagtttat
    27181 atcgccagcc ctgagagcca gcaaattcac gtctggaacc tgaatcatga aggcgcactg
    27241 acgctgacac aggttgtcga tgtgccgggg caggtgcagc cgatggtggt cagcccggac
    27301 aaacgttatc tctatgttgg tgttcgccct gagtttcgcg tcctggcgta tcgtattgcc
    27361 ccggacgatg gcgcactgac ctttgccgca gagtctgcgc tgccgggtag tccgacgcat
    27421 atttccaccg atcaccaggg gcagtttgtc tttgtaggtt cttacaatgc gggtaacgtg
    27481 agcgtaacgc gtctggaaga tggcctgcca gtgggcgtcg tcgatgtggt cgaggggctg
    27541 gacggttgcc attccgccaa tatctcaccg gacaaccgta cgctgtgggt tccggcatta
    27601 aagcaggatc gcatttgcct gtttacggtc agcgatgatg gtcatctcgt ggcgcaggac
    27661 cctgcggaag tgaccaccgt tgaaggggcc ggcccgcgtc atatggtatt ccatccaaac
    27721 gaacaatatg cgtattgcgt caatgagtta aacagctcag tggatgtctg ggaactgaaa
    27781 gatccgcacg gtaatatcga atgtgtccag acgctggata tgatgccgga aaacttctcc
    27841 gacacccgtt gggcggctga tattcatatc accccggatg gtcgccattt atacgcctgc
    27901 gaccgtaccg ccagcctgat taccgttttc agcgtttcgg aagatggcag cgtgttgagt
    27961 aaagaaggct tccagccaac ggaaacccag ccgcgcggct tcaatgttga tcacagcggc
    28021 aagtatctga ttgccgccgg gcaaaaatct caccacatct cggtatacga aattgttggc
    28081 gagcagggac tactgcatga aaaaggccgt tatgcggtcg ggcagggacc aatgtgggtg
    28141 gtggttaacg cacactaacc gctgatttaa ccggcgcagt ctctcctgcg ccggtgtatt
    28201 aacttatctc ctgtaacgca tgtctctggc gttcgacgat attggtccac aaattgtctt
    28261 tatcgtcagt ccacaaatta atcagcaagg caaaaaagcg ttcagctgcc ggagaaagca
    28321 cggcatcttt gcggcgaata atccccaatg tccgacgtat aacgggttcc accagtggga
    28381 taccaataat cgaagaatag ggcgcatggg gcattgccag accaggaagc gccgaaatcc
    28441 ccagtcctgc ctccactagt cctaatgacg tcgaaagatg acgcacttcg taaaaccagt
    28501 ccagcttcca gggcttgtcg gctagctgtt gttctatcaa caatcggttg ccgctggagg
    28561 aacgtacgcc aatcattttg taacccacta actcctgcca ttctacaagc tgctttttgg
    28621 ccaatggatg gtcacgccga caggccagca cgaatggctc gttgaccagt ggggtaaaat
    28681 caatggatga atttgtgacg ttgttcatgt ttatgccaaa gtctgattcg ttacacagca
    28741 ccgattccat gcaattattc gtgccttgtt ccagaatccg cactttaata ttgggataca
    28801 gctcattaaa tttaccgatt gccagcggta aaaaataaaa tactgcggtc ggaatacacg
    28861 ctaacgtcac cataccacga tgataagcat tcatatcacg aatattaaaa agcgtttcat
    28921 cgaatttctt tattaattcc cgcgcctccg ggagcaacct tttccctgct tttgttaacg
    28981 taaccttgcg agttgtacgc tcaaatagtt gaatatgtaa atcttcctcc atctttttta
    29041 ttcttcgcgt taatgcaggt tgcgtaatat tgagtgattt agcggcattg ttaaatgaac
    29101 tggactctgc cagtatgaca aatgccttca tacttgataa ttcatgcttc attattactc
    29161 cggaaaatgg aagcgacgat tttgggtggc tggccgttaa aaattttaac tgcatttagc
    29221 caacttaaat taatgaaaaa atgttattaa tcgttgagct aaagtcatta gagatgcttt
    29281 gcccttaatg taaccatatc gcaataagtt atgtttttaa attgagggca ttattatgaa
    29341 aaaaataccc tgcgtgatga tgcgaggtgg aacctcgagg ggcgcgttct tgttagcgga
    29401 acatttaccc gaagatcaaa cgcagcgcga taaaatattg atggcaatta tgggttccgg
    29461 taacgatctg gaaattgacg gtattggcgg cggtaatccg ctgaccagta aagtcgccat
    29521 tattagccgt tccagcgatc cgcgtgctga tgtcgattat ctgtttgctc aagttattgt
    29581 ccatgagcaa cgtgtcgata ccacgcctaa ttgtggcaat atgctgtctg gtgttggggc
    29641 attcgccatt gaaaatggtt tgattgcagc gacttcacca gttacccgcg tacgtatccg
    29701 caacgtcaat actggtacgt tcatcgaagc tgatgtgcaa acgccaaatg gtgttgtcga
    29761 gtacgagggt agcgccagaa ttgacggcgt accgggtact gccgcaccgg ttgcgctcac
    29821 tttcctgaat gccgccggaa ccaaaaccgg aaaagtcttc ccgactgata atcagattga
    29881 ttattttgac gatgtcccgg tgacctgtat cgatatggcg atgccagtcg tcattattcc
    29941 ggctgaatat ctgggaaaaa caggttatga attaccggcg gaactggatg ccgacaaagc
    30001 attattagca cgcattgaat ctatccgtct acaagcgggt aaagcaatgg gcttaggtga
    30061 tgtcagtaat atggttatcc ctaaacctgt gcttatttct ccagcgcaga aaggcggggc
    30121 aattaatgta cgttatttta tgccgcattc ttgccatcgc gcgctggcaa taaccggtgc
    30181 tattgctatt tccagtagtt gtgcattgga aggcaccgtc acccgacaaa tcgtcccttc
    30241 tgtaggatac ggcaatatca atattgaaca ccccagtggt gcgctcgacg ttcatttaag
    30301 taatgaaggt caggatgcca cgacgttacg cgcatctgtt attcggacga ccagaaaaat
    30361 attttccggt gaagtttatc ttccctgaaa aaattcgttg tcaggataag gacaatcaat
    30421 aaaggacttc tgtatgagtc atacagaaag aacaggattt taaatgaata agaaatcgtt
    30481 atggaagcta attctgatat tagcgatccc atgtattatt ggttttatgc cagctccggc
    30541 aggattaagc gaactggcgt gggtgctttt tggtatttac ctggcggcca ttgtgggtct
    30601 ggttatcaag cctttcccgg aacctgtcgt actgttaatt gccgttgctg cctcaatggt
    30661 ggtggtcggt aacttatccg acggtgcgtt taagaccacc gccgtattaa gcggttactc
    30721 ttcaggtact acctggctgg tgttctcggc gtttacctta agcgccgcat ttgtgaccac
    30781 cggtttaggt aaacgtattg cctatctgct gattggtaaa atcggtaaca ccacgctggg
    30841 tctgggttac gttacggtat tcctcgatct ggtactggct ccggcaacac cgtctaacac
    30901 cgcgcgtgcg ggcggcattg tgttaccgat catcaacagc gtggcggtgg ctttggggtc
    30961 cgaaccggaa aaaagtccgc gtcgtgtcgg acattacctg atgatgtcca tttacatggt
    31021 caccaaaacc accagctata tgttctttac cgcaatggcg gggaacattc tggcgctgaa
    31081 aatgatcaac gacattctgc acctgcaaat tagctggggt ggatgggcgc tggccgccgg
    31141 attgccgggc atcattatgc tgctggtcac cccgctggta atttacacca tgtatccacc
    31201 agaaattaaa aaggtggata acaaaaccat cgctaaagcg ggccttgccg aactgggacc
    31261 gatgaaaatc cgcgaaaaaa tgctgctcgg tgtctttgtg ctggcgctac tgggctggat
    31321 tttcagtaag tctctggggg ttgatgaatc cactgtggca atcgttgtta tggcgaccat
    31381 gctgctgctg ggtatcgtta cctgggaaga cgtggttaaa aataaaggcg gctggaatac
    31441 cttaatctgg tacggcggta ttatcggatt aagctcctta ttatcgaaag ttaaattctt
    31501 cgaatggtta gctgaagtct ttaaaaataa cctggcattt gatggtcacg gtaacgttgc
    31561 tttcttcgtt attattttcc tcagcattat cgtgcgttat ttcttcgctt ccggtagtgc
    31621 ctatatcgtt gctatgttac cggtatttgc catgctggcg aacgtctccg gcgcaccgtt
    31681 aatgttaacc gcgctggcac tgttgttctc caactcctat ggcggcatgg ttactcacta
    31741 tggcggcgcg gcaggtccgg tcatctttgg cgtgggttat aacgatatta aatcctggtg
    31801 gttggtcggt gcggtactga cgatattaac cttcctggtg catatcaccc tcggcgtgtg
    31861 gtggtggaat atgctgatcg gctggaacat gctgtaaata ttctcgtcat acttcaagtt
    31921 gcatgtgctg cgtctgcgtt cgctcacccc agtcacttac ttatgtaagc tcctggggat
    31981 tcactcgctt gtcgccttcc tgcaactcaa attatttaga gtatatccat ttattatctt
    32041 tctgcgcact tcacggtgcg cagatatctg gagcatttga tgatcaagtt atctgaaaaa
    32101 ggcgtgtttc tcgccagtaa taacgaaata attgctgaag aacatttcac cggcgaaatt
    32161 aaaaaagaag aagccaaaaa aggcactatt gcctggtcta ttctctcttc gcataatacg
    32221 tccggaaata tggataaact taaaattaag tttgattcat tagcctctca cgatattacc
    32281 tttgttggta ttgtacagac cgctaaagcg tccggtatgg aacgtttccc gctgccgtat
    32341 gtgctgacca actgccataa ctcactctgc gccgtcggcg gcaccattaa cggtgatgac
    32401 catgtttttg gtttatcggc agctcagcgt tatggcggta tttttgtgcc tccgcatatt
    32461 gcggtcatcc atcaatatat gcgtgagatg atggcaggcg gcggcaaaat gatcctcggg
    32521 tcagacagcc acacccgtta cggtgcatta gggacaatgg cagtcggtga gggcggtggt
    32581 gagttggtaa aacagctgct taatgacacc tgggatatcg actatccggg agttgttgcg
    32641 gtgcatctga ccggaaaacc agcgccgtat gtggggccgc aggatgtggc gctggctatc
    32701 attggcgcgg tgttcaaaaa cggttacgtc aaaaacaaag tcatggagtt cgttggaccg
    32761 ggcgttagcg cgctctctac cgatttccgt aacagcgttg acgtgatgac cacggaaacc
    32821 acctgtttaa gctccgtctg gcaaactgat gaagaagtgc ataactggct ggcgctgcac
    32881 ggtcgcggcc aggattactg ccagcttaac cctcaaccga tggcgtacta cgatggctgc
    32941 atcagcgttg atttaagcgc catcaaacca atgattgcgc tgccgttcca cccgagcaac
    33001 gtgtatgaaa tcgacacact gaaccagaac ctgaccgaca ttctgcgtga gattgaaatt
    33061 gagtccgaac gcgtggcgca cggtaaagcc aaactctcgc tgctggataa agtggaaaat
    33121 ggtcgcctga aagtgcagca ggggattatc gcgggctgtt ctggcggtaa ctacgaaaac
    33181 gtcatcgcgg cggcgaatgc actgcgcggt caatcctgtg gcaatgacac cttctcgctg
    33241 gcagtttacc cgtcatcaca gccggtgttt atggatctcg ccaaaaaagg tgtggtagca
    33301 gatttgattg gcgcaggcgc aatcatcaga accgcgttct gcggcccatg ctttggcgcg
    33361 ggcgatacgc caatcaacaa cggattaagt attcgccaca ccacgcgtaa cttcccgaac
    33421 cgcgaaggct ctaagccagc taatgggcag atgtcagcgg tggcgttgat ggacgctcgt
    33481 tctatcgctg cgactgcggc aaacggtggc tatttaacct ctgccagcga acttgattgc
    33541 tgggacaacg tgccggagta cgccttcgat gtaacgccgt ataaaaaccg tgtttatcag
    33601 ggctttgtga aaggggcaac tcagcaaccg ctgatttacg gaccgaacat taaagactgg
    33661 ccggaattgg gtgcgctgac tgacaatatc gtcctgaaag tgtgctcgaa gatcctcgac
    33721 gaagtgacca ccaccgacga actgattcct tccggtgaaa cctcttctta tcgttcaaat
    33781 ccgattggtc tggcggagtt taccctgtca cgccgcgatc ccggttatgt tggcagaagt
    33841 aaagcgactg ctgagctgga aaatcagcgt ctggcgggga atgtcagcga gctgacagag
    33901 gtgtttgcgc gcattaagca gattgctggt caggagcata ttgatccgct gcaaactgaa
    33961 attggcagca tggtatatgc ggtgaaacta ggcgatggtt ctgcgcgtga acaggcggcg
    34021 agctgccagc gtgtgattgg cggtctggcg aatattgccg aagagtacgc gactaaacgc
    34081 taccgttcta acgtcatcaa ctgggggatg ttaccgctgc agatggcgga agtgccaacc
    34141 tttgaagtgg gggattacat ttacatccct ggcattaaag cggcgctgga taatccgggt
    34201 acgacgttta aaggttatgt gatccatgaa gatgcgccgg taacggaaat tacgctctat
    34261 atggaaagtc tgactgctga agagcgcgag attatcaagg cgggtagttt gattaacttc
    34321 aataaaaacc gtcagatgta aaaagcgcca tgtgaatgta ggtcgcattc ggcacttatt
    34381 gtcggatgcg atgcttgcgc atcttatccg acctacgaat cgcatcgaat ctgtaggccg
    34441 gataaggcgt ttacgccgca tccggcaaat agttaatagc tcttacttct tcgcctctgc
    34501 aaccacttta ctacccacgc cgcggttatt gtattcccac atgcggttgt agttagtgtc
    34561 attcagattg cgctgtattt cgtcgttatc atctacgctg ccggtattac ccgcaaacgg
    34621 acgattagag atcaccgcat cggcccacgg tttagccgtg ttaaaacctt cgttgatggc
    34681 gctatcacgg atcaccacct gaccgttggt attggcatca acatccagcg agcggcccag
    34741 ttgcgccaca ccatcaccga aagcattgaa acggctgttt acggcgagga aaccgtagta
    34801 aatgttggac agcgtagccg gtgcaaacac atacgcttct tgctgagtac gtgagttcac
    34861 cacgcggaat tcggtgttat cgaacaccac tgcgccgcga ccagaaacga tatccacatc
    34921 cccttcaatg tagctgttgg tcaccagcgt acgcggctga cggttggttt ccagacggtt
    34981 ctgcacaccg ctgttggtga caaagaaggt gttctgacga ccgagaatgt taacgttgtt
    35041 aatctgtacc tggtcaccat cagtacgcag tgccaccgcc ggatggttac ctgcatctac
    35101 gctatcgccc agcgtgtttt cgatggtcag attttgcagt tgcaggccat tgttttgtga
    35161 ccagaagacc gcagagcaga gaacaccgat actgtcgctg cgtttgctct ggcagctatc
    35221 gtacatatac cacgctggtt tacctggcat atatttgccg cgcgggttga cgtcgtgacg
    35281 ccagtcggca gggctcatgc ccccatcaag ggaaagccca atcttcacat caatcggttt
    35341 ttcacctgta ccgtacagag taattccacc cggagcagca gggacataca ccgttccctg
    35401 atactcacca ggcatcacgg caatatactg gcgcttgtta gtgcgcttga taattgccgc
    35461 atctaccgcc gcctgaatcg tggtatgcgt tacaccttga gtacccgccg ggccgacaac
    35521 aaagtcaggt tgcgcaggca gggtaatcgg ggaaggattc cacgctgcag cacctggtgt
    35581 cagggatgca aaatagtgtt gagcatcgaa attctgcgct tcttttgccg acagaatcgg
    35641 gcgagaagag gtaccaggcg cggtttgatc agaaggacgt tgatcgggtg gtgttgagct
    35701 acaggcggtc agcgtcacgc caaaagccaa tgccagcgcc agacgggaaa ctgaaaatgt
    35761 gttcacaggt tgctccgggc tatgaaatag aaaaatgaat ccgttgaagc ctgctttttt
    35821 atactaagtt ggcattataa aaaaacattg cttatcaatt tgttgcaacg aacaggtcac
    35881 tatcagtcaa aataaaatca ttatttgatt tcaattttgt cccactccct gcctctgtca
    35941 tcacgatact gtgatgccat ggtgtccgac ttatgtccga gaagatgttg agcaaactta
    36001 tcgcttatct gcttctcata gagtcttgca gacaaactgc gcaactcgtg aaaggtaggc
    36061 ggatcccctt cgaaggaaag acctgatgct tttcgtgcgc gcataaaata ccttgatact
    36121 gtgccggatg aaagcggttc acgacgagta gatgcaatta tggtttctcc gccaagaatc
    36181 tctttgcatt tatcaagtgt ttccttcatt gatatcccga gagcatcaac atgcaatgtt
    36241 gtagggatgg caatttttac gcctgttttg ctttgttcga cataaagata tccatctacg
    36301 atatcagacc acttcatttc gcataaatca ccaactcgct gcccggtaac aacagccagt
    36361 tccattgcaa gtctgagcca acatggtgat gattctgctg cttgataaat tttcaggtat
    36421 tcgtcagccg taagtcttga tctccttacc tctgattttg ctgcgcgagt ggcagcgacc
    36481 gggtttgttg ttatatggcc ttcagctatt gcctctcgga atgcatcgct cagtgttgat
    36541 ctgattaact tggctgacgc cgccttgccc tcgtctatgt atccattgag cattgccgca
    36601 atttcttttg tggtgatgtc ttcaagtgga gcatcaggca gccccctcct tattgcttta
    36661 attttgctca tgtaatttat gagtgtcttc tgcttgattc ctctgctggc gaggattttt
    36721 tcgtagcgat caagccatga atgtaacgta acagaattat cactgttgat tctcgctgtc
    36781 agaggcttgt gtttgtgtcc tgaaa
//
LOCUS       DAZUDJ010000050        36344 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.050, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000050 DAZUDJ010000000
VERSION     DAZUDJ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36344
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.050"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..266)
                     /locus_tag="ACHY1N_003223"
     CDS             complement(<1..266)
                     /locus_tag="ACHY1N_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HFS4045487.1"
                     /translation="MQQLSFLPGEMTPGERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPR"
     gene            complement(282..761)
                     /locus_tag="ACHY1N_003224"
     CDS             complement(282..761)
                     /locus_tag="ACHY1N_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HFS4045488.1"
                     /translation="MKTVSQNTPTIYSATTPENNPPQLVASLVPDEQRISFWPQHFGL
                     IPLWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMN
                     GNRAEMSPEAAGIAACLMTYSHHACRTENYAMTVHYYRLRDYALQHPECSAIMRIID"
     gene            complement(843..1664)
                     /locus_tag="ACHY1N_003225"
     CDS             complement(843..1664)
                     /locus_tag="ACHY1N_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF932 domain-containing protein"
                     /protein_id="HFS4045489.1"
                     /translation="MRLASRFGYAANQIRRDRPLTHEELIRHVPSIFGEDRHTSRSER
                     YAYIPTITVLENLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEII
                     LLNSHDGTSSYQMLPGYFRFVCQNGCVYGQSLGKVRVPHRGNVVEKVIEGAYEVVGVF
                     DQIEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLW
                     SAYQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETMLESLR"
     gene            complement(1885..2295)
                     /locus_tag="ACHY1N_003226"
     CDS             complement(1885..2295)
                     /locus_tag="ACHY1N_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045490.1"
                     /translation="MKTFIKTLLVAVTILFSVFATAKQVKLPNNIKYVNTTEAFSCTE
                     IDGMNCQTKNQFNYKDNSYVFVLERGGAWCYDYTVSVVNLKTGKAQMIEYGDNQLCSG
                     SNKPFFEIKNGVPTVGVIDTSGKPVVVAQDKLKI"
     gene            complement(2311..2994)
                     /locus_tag="ACHY1N_003227"
     CDS             complement(2311..2994)
                     /locus_tag="ACHY1N_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045491.1"
                     /translation="MKLPVKLLMSLISLVSVIARAGEYKNYSRDEIKYWRYTSYKGGK
                     LPEGFTDEKFSSAIYNGRIFTMKRLHTLMLFLAVLFTGFNFNAEAATVKQALSCNPEA
                     WAEQPGACPSTYELYEGDATYKAAIDKALKPVGLSGMFGKGGYMDGPGGGITPVNING
                     TVWFQGDGCKANTCGWDFIVTLYNPKTHEVVGYRYFGLDDPAYLVWFGEIGVHEFAYL
                     VKNYVAAVN"
     gene            complement(3130..4200)
                     /locus_tag="ACHY1N_003228"
     CDS             complement(3130..4200)
                     /locus_tag="ACHY1N_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFS4045492.1"
                     /translation="MSTEMKTGLVLSGGGAVGAYQAGVVKALAECGTQISMVSGASIG
                     AFNGAIIVASPDLSEAAVRLEALWDHLGNNQVLSVNRLVYFSLLKKLFQAMNLCQIPG
                     RAGALLTTLLRHISTINGFDNLMAQPLLSDEPLTALMDHYLDTDALADGLPLYVSLYP
                     TEGGMQDIIDCIRAELGVGTTKNAVFQHIQSLPRGQQKEALLASAALPLLFRPREVQG
                     TMFGDGGMGGWRNMQGNTPVTPLVDAGCNMVIVTHLSDGSLWDRQAFPDTTILEIRPR
                     KRLKYAGDGGNSGGLLSFTSAHTDAWRQQGYEDTMLAMEHIRKPLAARQALTRSEAVL
                     QKSLDITEEADLALRNAMARIK"
     gene            complement(4197..5102)
                     /locus_tag="ACHY1N_003229"
     CDS             complement(4197..5102)
                     /locus_tag="ACHY1N_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase regulator RdcB family
                     protein"
                     /protein_id="HFS4045493.1"
                     /translation="MISPFIQQIADNRVCQVLTCLPEKFVVDFANGIDVAQEHIRTAG
                     ERTFFRRLKEGLTGEGAARQNAINASLAQGVEASLRWLTEMTTSLATTNYAITQVNDR
                     VSSLVSDTARLAHYSADTREQLLTLADQVHHKLNHLEEKLHRVDQVQRAQLHLEQIFS
                     WWSAGRYASFSPAGRCYVALEELRWGAFGDVIRQSETGQVNQLLDILRHKALTQMAQE
                     SGGSATVRLNTLDWLGGQGREQADNEWHDAINWLGDWCSEEQHPVIWSTTQAAEHLPV
                     RMPRLCSAERLSESMVDEIFQKGAA"
     gene            complement(5099..7495)
                     /locus_tag="ACHY1N_003230"
     CDS             complement(5099..7495)
                     /locus_tag="ACHY1N_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HFS4045494.1"
                     /translation="MHEKNIALLCDEADRLLQLNINLLRQMVEEPDVLSDSKNENRLL
                     FDKQKALKRIEELEGEQIKTARREMVLAVVGTMKAGKSTTINAIVGQEILPNRNRPMT
                     SVPTLIRHVPGKTEPVLHLEHIQPVRNLLITLQEKLATPAGQQVAQTLQQTGDTRELL
                     DILTDDGWLKNEYHGEEEIFTGLASLNDLVRLAAAMGTEFPFDEYAEVQKLPVIDVEF
                     SHLVGMDACQGTLTLLDTPGPNEAGQPQMEVMMRDQLQKASAVLAVMDYTQMNSKADE
                     DVRKELNAIADVSAGRLFVLVNKFDEKDRNGDGADAVRQKVPAMLNSDVLPASRVYPG
                     SSRQAYLANRALHELRKNGTLPVDEAWVDDFIRGAFGCMKKEYVCKDSELATEGATDL
                     WEGSLIDQLITEVIQSSHSRAAALAVDSAAAKLMQNAENISEYLLLRHQGLQQSIQSL
                     QSHITSLLADIREIADCQEQMTTDVRMAMEEIDTKTRELLTGVCTSLEEELNDYFRSG
                     KRKEQQMLEEEDAEQRRSQSGLWGKISQWSGINNQGREDYRKRDFAPDSPEIKFSDRR
                     EALELMTQIESTVTSLHREAEAQFRPELEKIVSGIETGFRGTALYATENIAGRINARL
                     EDEGFTVKISFPAVSQLQTRLAVKINLSALMEERTETVTRRRRQSGVWGTVCRWFGTS
                     DLGWENYDEDVSRSVININKVREEVMSLTRAYFGELQASIEQDINQPVRQEIDAFFCA
                     FREKVEQLRNTLIQSSEDHKRDQQAQERLTGRLQALNERVPELITDSKALREELETML
                     "
     gene            complement(7713..8584)
                     /locus_tag="ACHY1N_003231"
                     /pseudo
     CDS             complement(7713..8584)
                     /locus_tag="ACHY1N_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
     gene            complement(8668..9819)
                     /locus_tag="ACHY1N_003232"
     CDS             complement(8668..9819)
                     /locus_tag="ACHY1N_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045495.1"
                     /translation="MGKELDDICTSCPYIDAVKRHKQQLGAIEEYTQWLKKEPRASYF
                     FLFQLYTRIHNTFFSQKQQLPFTPGGTHCPEPDVTLRDLTLSPGYHSDYAPQPIPEMD
                     SSAVVPPTNENTSPPEDTPDNTPAGGNTGQAEKTRNAGLTPIPEKRSGMPPEHLRFAT
                     GFPSQPKIAGPREKPMRTVHPDKIYREIIWFCSSYLLKSGPEATRTIINSVFSEWASI
                     NNDYPSPFSWVDSRDSEQCDWLWNAMQVRCVGTPLNPLTPEQKYWFACATFDNWEGWN
                     EQQVQFLLESNPRRNRAKFTQVSFQAPRIQHKAILLDELKSAREQQKRRDERADGSVP
                     LKLSGKIHKQLESIARSRGVLPKKLLNEMIEQAYHDLVATRQNSQIDSR"
     gene            complement(11087..11356)
                     /locus_tag="ACHY1N_003233"
                     /pseudo
     CDS             complement(11087..11356)
                     /locus_tag="ACHY1N_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            11442..12464
                     /gene="istA"
                     /locus_tag="ACHY1N_003234"
     CDS             11442..12464
                     /gene="istA"
                     /locus_tag="ACHY1N_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100 family transposase"
                     /protein_id="HFS4045496.1"
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEP
                     PKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRAFIR
                     SLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMR
                     YDTLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFS
                     PRLCRPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVA
                     NQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDENLVNFDKHPLHHPLSIYDS
                     FCRGVA"
     gene            12461..13243
                     /gene="istB"
                     /locus_tag="ACHY1N_003235"
     CDS             12461..13243
                     /gene="istB"
                     /locus_tag="ACHY1N_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
                     /protein_id="HFS4045497.1"
                     /translation="MMMELQHQRLMVLAGQLQLESLISAAPALSQQAVDQEWSYMDFL
                     EHLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIER
                     NENIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQ
                     RGVMAPRLLIIDEIGYLPFSQKEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGD
                     AALTSAMLDRILPHSHVVQIKGESYRLRQKRKAGVIAEANPE"
     gene            13282..13434
                     /locus_tag="ACHY1N_003236"
     CDS             13282..13434
                     /locus_tag="ACHY1N_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045498.1"
                     /translation="MDHFSSVVDICGQSFWLAVQGMFSGYRVPQSRDIAPIVTFQIDR
                     GLKMWH"
     gene            complement(14172..14774)
                     /locus_tag="ACHY1N_003237"
     CDS             complement(14172..14774)
                     /locus_tag="ACHY1N_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045499.1"
                     /translation="MKQQYQTRYELLHENYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRSSPSLDDDLVVNLCTSEHLLVHHPMLEG
                     ILLSECERLKQHSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLDDWTKNLKHK
                     SEKDLEQWIIARQGQSEPLTNLMDQYVLMAYRTSVDAAHS"
     gene            complement(14868..15074)
                     /locus_tag="ACHY1N_003238"
     CDS             complement(14868..15074)
                     /locus_tag="ACHY1N_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4045500.1"
                     /translation="MATPVSLMDDQMVDMAFITQLTGLTDKWFDKLIKDGGFPAPIKM
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            complement(16201..16401)
                     /locus_tag="ACHY1N_003239"
     CDS             complement(16201..16401)
                     /locus_tag="ACHY1N_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045501.1"
                     /translation="MVIRKKKCRDCGNAITHNTVCCPYCGSVDPFGYYRNTDRIVTIL
                     LALIIVVLLTTVSVSVYILCSW"
     gene            16601..17170
                     /locus_tag="ACHY1N_003240"
     CDS             16601..17170
                     /locus_tag="ACHY1N_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HFS4045502.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLRFPDVPAATD
                     AAVISRFINALKARIDAYQKRKHREGKRVHPTTLHYVWAREFGECKGKKHYHLMLLVN
                     RDTWCRAGDYRAPGSLAGMIKQAWCSALGVDVGCHATLVHFPAWPAVWLERDDDTGFQ
                     QVLERADYLAKEHTKAHCTGERNFGCSRS"
     gene            17430..17831
                     /locus_tag="ACHY1N_003241"
     CDS             17430..17831
                     /locus_tag="ACHY1N_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc ribbon protein"
                     /protein_id="HFS4045503.1"
                     /translation="MYAKSFIALDGNGRLTGARTAQAAPYANYTCHLCGSALRYHPQY
                     DTELPWFEHTDDRLTEHGQQCPYVRPERREIQLIKRLQQFVLDALPVVRKASWHCRQC
                     HHDYYGERYCTHCQTGGFSIPRTTQEEICEF"
     gene            17819..18226
                     /locus_tag="ACHY1N_003242"
     CDS             17819..18226
                     /locus_tag="ACHY1N_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFS4045504.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDVLCCVSCGCPLTLQR
                     GNDGQPPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDENYEGEKCCPSCGTGVYSREGGQEGNWKDRN"
     gene            18510..20129
                     /locus_tag="ACHY1N_003243"
                     /pseudo
     CDS             18510..20129
                     /locus_tag="ACHY1N_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            20209..20501
                     /locus_tag="ACHY1N_003244"
                     /pseudo
     CDS             20209..20501
                     /locus_tag="ACHY1N_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312320.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
     gene            complement(20541..21575)
                     /locus_tag="ACHY1N_003245"
     CDS             complement(20541..21575)
                     /locus_tag="ACHY1N_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase"
                     /protein_id="HFS4045505.1"
                     /translation="MKDYLQTVTGPVAREDMGLTLPHEHLFNDLSSVVDAPCYPFSQQ
                     LVDKKVTAEIQWALKHDPYCCADNMDRKPIEDVIFEINNFISLGGRTIVDATGSESIG
                     RDAQALREVALKTGLNIVASSGPYLEKFESQRIHKTVDELATTIDKELNQGIGDTDIR
                     AGMIGEIGVSPTFTEAEHNSLRAASLAQINNPHVAMNIHMPGWLRRGDEVLDIVLGEM
                     GVSPNKVSLAHSDPSGKDVAYQRKMLDKGVWLEFDMIGLDITFPKEGIAPGVQETADA
                     VAHLIELGYADQLVLSHDVFLKQMWAKNGGNGWGFVPDVFLAYLAERGVDKTILKKLC
                     IDNPGRLLTA"
     gene            complement(21578..22543)
                     /locus_tag="ACHY1N_003246"
     CDS             complement(21578..22543)
                     /locus_tag="ACHY1N_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFS4045506.1"
                     /translation="MKKNKYSTPLWVLATILAGMLSPMQSAVNGQLGHWLQDGNACAV
                     ISFASGLVVMFFIIMARKEIRQQFAAIPSLIKNRKVPLWNWFAGLCGAMVVFSEGASA
                     SALGVATFQTALISALLLSGLLCDRFGIGVDEKKYFTPYRIIGALFAVIATIFVVSPQ
                     WHSTSFILLAILPFLAGLLAGWQPAGNAKVAEATGSMLVSITWNFIVGFCVLGTALAI
                     RVALGHVTVQLPDVWWMYLGGPLGLMSIGLMAILVRGLGLLMLGVASTAGQLLGSVLI
                     DVLIPSLGNTVYLVTIIGTLFALVGAIVTTIPEYRASKTMKKMEV"
     gene            complement(22600..23358)
                     /locus_tag="ACHY1N_003247"
     CDS             complement(22600..23358)
                     /locus_tag="ACHY1N_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HFS4045507.1"
                     /translation="MNNTKKSLKVLFIGESWHIHMIHSKGYDSFTSSKYEEGATWLLQ
                     CLKNSQVDVTYMPAHTVQIAFPEDVAQLEQYDAIVISDIGSNTFLLQNDTFYQLRIKP
                     NALELIKEYVNNGGGLLMIGGYLSFMGIEAKANYKNTVLADVLPVTMLDGDDRVEKPE
                     GVIAQPSQPDHPVIKGFSEYPFFLGYNRAIAKENAEVVLTINNDPLLVFGNYHNGKIA
                     CFMSDCSPHWGTQQFMSWPFYTALWVNILTHIAR"
     gene            complement(23372..24586)
                     /locus_tag="ACHY1N_003248"
                     /pseudo
     CDS             complement(23372..24586)
                     /locus_tag="ACHY1N_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462448.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
     gene            complement(24782..25142)
                     /locus_tag="ACHY1N_003249"
                     /pseudo
     CDS             complement(24782..25142)
                     /locus_tag="ACHY1N_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            25204..25894
                     /locus_tag="ACHY1N_003250"
                     /pseudo
     CDS             25204..25894
                     /locus_tag="ACHY1N_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(26082..26582)
                     /locus_tag="ACHY1N_003251"
                     /pseudo
     CDS             complement(26082..26582)
                     /locus_tag="ACHY1N_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310819.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
     gene            27762..27950
                     /locus_tag="ACHY1N_003252"
                     /pseudo
     CDS             27762..27950
                     /locus_tag="ACHY1N_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904641.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            27929..28102
                     /locus_tag="ACHY1N_003253"
                     /pseudo
     CDS             27929..28102
                     /locus_tag="ACHY1N_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524956.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
     gene            28254..28799
                     /gene="cobU"
                     /locus_tag="ACHY1N_003254"
     CDS             28254..28799
                     /gene="cobU"
                     /locus_tag="ACHY1N_003254"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HFS4045508.1"
                     /translation="MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARI
                     EHHRQGRPEHWRTVERWQHLDELIHADINPNEVVLLECVTTMVTNLLFDYGGDKDPDE
                     WDYQAMEQVINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
                     QLAAAANEVWLVVSGIGVKIK"
     gene            28796..29539
                     /gene="cobS"
                     /locus_tag="ACHY1N_003255"
     CDS             28796..29539
                     /gene="cobS"
                     /locus_tag="ACHY1N_003255"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0051073 - adenosylcobinamide-GDP
                     ribazoletransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HFS4045509.1"
                     /translation="MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLL
                     GAISGLVFMVLQAWCGAPLAALFSVLVLVLMTGGFHLDGLADTCDGVFSARSRDRMLE
                     IMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRH
                     RYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQL
                     LKRTLGGQTGDTLGAAIELGELVFLLALL"
     gene            29551..30630
                     /gene="cobT"
                     /locus_tag="ACHY1N_003256"
     CDS             29551..30630
                     /gene="cobT"
                     /locus_tag="ACHY1N_003256"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HFS4045510.1"
                     /translation="MQTLADLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALAI
                     QLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVL
                     AAQAGANVYVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRHQAEKLLLDVICYT
                     RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRAPEEVVGIGANLPTDKLANKIDVV
                     RRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCGLPVLLDGFLSYAAALAAC
                     QMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACA
                     IYNNMGELAASNIVLPGNTTSDLNS"
     gene            30692..31627
                     /gene="ldtA"
                     /locus_tag="ACHY1N_003257"
     CDS             30692..31627
                     /gene="ldtA"
                     /locus_tag="ACHY1N_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310812.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HFS4045511.1"
                     /translation="MMRRVNIFCSFALLFASHTSLAVTYPLPPEGSRLVGQSFTVTVP
                     DHNTQPLETFAAQYGQGLSNMLEANPGADVFLPKSGSQLTIPQQLILPATVRKGIVVN
                     VAEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYA
                     KRGESLPAFVPAGPDNPMGLYAIYIGRLYAIHGTNANFGIGLRVSQGCIRLRNDDIKY
                     LFDNVPVGTRVQIIDQPVKYTTEPDGSNWLEVHEPLSRNRAEYESDRKVPLPVTPSLR
                     AFISGQEVDVNRANAALQRRSGMPVQISSGSRQMF"
     gene            complement(31682..31757)
                     /locus_tag="ACHY1N_003258"
     tRNA            complement(31682..31757)
                     /locus_tag="ACHY1N_003258"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31722..31724),aa:Asn,seq:gtt)
     gene            32084..33001
                     /gene="nac"
                     /locus_tag="ACHY1N_003259"
     CDS             32084..33001
                     /gene="nac"
                     /locus_tag="ACHY1N_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen assimilation transcriptional regulator
                     NAC"
                     /protein_id="HFS4045512.1"
                     /translation="MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELN
                     QQLLIRTKRGVTPTDAGKILYTHARAILRQCEQAQLAVHNVGQALSGQVSIGFAPGTA
                     ASSITMPLLQAVRAEFPEIVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQA
                     LLKEDLFLVGTQDCPGQSVDVNAIAKMNLFLPSDYSAIRLRVDEAFSLRRLTAKVIGE
                     IESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANL
                     SPQAQAVKELLMSVISSPVMEKRQWQLVS"
     gene            33103..34053
                     /gene="cbl"
                     /locus_tag="ACHY1N_003260"
     CDS             33103..34053
                     /gene="cbl"
                     /locus_tag="ACHY1N_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator Cbl"
                     /protein_id="HFS4045513.1"
                     /translation="MNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDEL
                     GIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHT
                     QARYSLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVA
                     FPWFRWHHSLLVPHDHPLTQISPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLLA
                     DIVLSAQDSDVIKTYVALGLGIGLVAEQSSGEQEEENLIRLDTRHLFDANTVWLGLKR
                     GQLQRNYVWRFLELCNAGLSVEDIKRQVMENSEEEIDYQI"
     gene            complement(34091..34166)
                     /locus_tag="ACHY1N_003261"
     tRNA            complement(34091..34166)
                     /locus_tag="ACHY1N_003261"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34131..34133),aa:Asn,seq:gtt)
     gene            34167..34307
                     /locus_tag="ACHY1N_003262"
     CDS             34167..34307
                     /locus_tag="ACHY1N_003262"
                     /inference="COORDINATES: protein motif:HMM:NF039930.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5951 family protein"
                     /protein_id="HFS4045514.1"
                     /translation="MAVEAHLNGEKSFVKPDFLIPQLFAVSINSLLHLQTICWRKSLQ
                     LC"
     gene            34327..35814
                     /gene="yeeO"
                     /locus_tag="ACHY1N_003263"
     CDS             34327..35814
                     /gene="yeeO"
                     /locus_tag="ACHY1N_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001323172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic metabolite efflux MATE transporter YeeO"
                     /protein_id="HFS4045515.1"
                     /translation="MWFHFLQLRSALNISSALRQVVHGTRWHAKRKSYKVLFWREITP
                     LAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVV
                     VAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALA
                     LTYLELTVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW
                     PGLGFVGAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIG
                     IPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITG
                     RRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAGLMASFYTQDPQVKHVVVILI
                     WLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVG
                     VWMGMFADWAVRAVLFYWRMVTGRWLWKYPRSEPQKCEKKPAVSE"
     gene            35915..35990
                     /locus_tag="ACHY1N_003264"
     tRNA            35915..35990
                     /locus_tag="ACHY1N_003264"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35948..35950,aa:Asn,seq:gtt)
BASE COUNT         8957 a         8671 c         9158 g         9558 t
ORIGIN      
        1 cggggatgga cttccgtgcg gttgatggtg ccggtaaaga gggtttcacc ggcaatcagt
       61 tgattctggt tattcagata cagcacccgg aattcttcac gctccagtcc cgccatgttc
      121 agaatcagcc attcccgtgc tgcacgggtg gaggtgaagg ccacgccggg ttcatgaaga
      181 tggcggtcca gggttttcag ggcccgttga atgaggctgc gctcgccggg cgtcatctct
      241 ccgggcagaa aggaaagttg ttgcattgtg cttctctcca ttcagtcgat gatgcgcata
      301 atggcgctgc attccggatg ctgcagggcg taatcccgca accggtaata atggaccgtc
      361 atggcataat tctccgtacg acaggcatga tgactgtacg tcatcagaca ggcggcaata
      421 ccggcggctt ccgggctcat ttctgcgcgg ttaccgttca tggcattgaa cagtacccat
      481 gtttcgtcat catcgtcatc cggttcgggt gccataaatg ccccgccgtt gttcagggtg
      541 tacagattcc agataccacc gcagtagtct tcgcacagac ggtccatcca gccgaagaca
      601 cggggctcca gggtcaccca cagtggaatg aggccaaaat gctgcggcca gaagctgatg
      661 cgctgttcat cagggacgag gctggcaacc aactgaggcg gattattctc tggtgttgta
      721 gctgaataaa ttgtgggggt attctgagaa acggttttca tgagataact ccttaaataa
      781 caaataaatg tgtgtttttc aggaacgaaa gctgaatgat tccctcactc agggaaacgg
      841 catcagcgca ggctctccag catcgtttct gccatcaccc acaatgcgcg attgagctta
      901 atgtcggtat caatgctgtg aatggcccgg gtatggatac gttttccttt tgcactgcga
      961 ccggaaatcc cgcctttcag catattctcc tggatggtct gatatgcgct ccacaggtcc
     1021 ttaccgtaat cctcccggcg tcgcggcgtc agaatgtcgg cggtggtgac gggctgatgt
     1081 tcgtcaccat aacggtaagt cagtgccgcc tgtgccagcg cctggcgtgc cggtggcggc
     1141 aggaccagcg actgcatggc atcacgcttc tcctctatct ggtcaaacac gcccaccacc
     1201 tcgtaagccc cttcgataac tttctccact acatttcccc ggtgtggaac acgcactttc
     1261 cccagagact ggccatagac gcacccgttc tggcagacga acctgaagta acccggcagc
     1321 atctggtagc tggaggtacc gtcatgagag ttgagcagaa taatttcagg gacatgttct
     1381 ccgtttatct ctccggcccg ccgcagacgc agcatgtgtt ttgtgtatcc ccggcggccc
     1441 gggtcgcgca cacgggtctg gcaggcgaag aacggctgaa agccttcccg ctgcagattt
     1501 tccaggacgg taatggtggg aatgtacgca taccgttcac tgcgggaggt gtgccggtct
     1561 tccccaaaaa tactgggtac atggcgtatc agttcttcat gtgtcagcgg acggtcacgg
     1621 cgtatctggt ttgcagcata accaaaacga cttgctaatc gcatactttg ctccttatcg
     1681 gtggttaaga tttactggtg caataaatga aaaaagccgc gtctcccgga gaagacgcgg
     1741 cctgacgggt gaaatgaata aggtttattg tctgagaggc ctttcactgg cgagccacgc
     1801 attaagcggc tttccggtaa caatggctgg ggctgtattt acctttgata ttaataatgt
     1861 gcagagaaac gcatggttta ctccttagat tttaagtttg tcctgggcta caacgacagg
     1921 ttttccggat gtgtcgatga ctcctaccgt cggtacgcca tttttgattt cgaagaacgg
     1981 tttgttgcta cctgagcaca gttgattgtc cccgtattca atcatttgtg ctttcccggt
     2041 tttcaggtta actaccgaga cagtgtagtc gtagcaccag gcaccaccac gttcaagcac
     2101 gaaaacatag ctgttatctt tatagttgaa ctgattcttt gtctggcaat tcataccgtc
     2161 aatttcggta caggaaaacg cttctgtagt attaacgtat ttgatgttat ttggcagttt
     2221 tacttgtttc gcagtagcga agacagagaa cagaatagtt acagcaacga gtaaagtttt
     2281 gataaaagtt ttcatgatag actccttaaa ttagttaacc gcagctacgt agtttttcac
     2341 cagatacgcg aattcatgca cgccaatttc accgaaccaa accaggtagg ccgggtcatc
     2401 taaaccaaag taacggtagc caacaacttc atgggttttt gggttataga gtgttacgat
     2461 aaagtcccag ccgcaggtat tggctttgca accgtcgccc tggaaccaga ctgtaccgtt
     2521 aatgtttact ggcgtgatac ctccaccagg gccatccata tagccgcctt taccgaacat
     2581 gccgctcagt ccgaccggtt ttaatgcttt gtcgatagcg gctttgtagg tagcgtcacc
     2641 ttcgtacaac tcgtacgttg atggacacgc tccaggttgt tcagcccagg cttccgggtt
     2701 acaactaaga gcttgtttta cggtagccgc ttctgcgtta aagttaaagc ccgtgaacag
     2761 aaccgccaga aataacataa gggtatgtaa acgtttcatt gtaaatattc ttccgttgta
     2821 aatggcgctg gaaaatttct catcagtgaa accttccgga agtttccccc ccttgtatga
     2881 tgtatatcgc cagtatttta tttcatcccg gctgtaattt ttatattccc cggcacgtgc
     2941 aataacgctg accagagata taaggctcat taataacttt acaggtaatt tcataattaa
     3001 atttccagtg agtgaattga caggtgaggg gtaaaacttt ctctcaggta atatatatct
     3061 gaaaatattt tcaataacac cagacaggaa aaacaccacc acaggcggtg gcgtttcttt
     3121 ggggcgtctt tatttaatcc gggccatcgc gtttctcagt gccaaatctg cctcttccgt
     3181 tatatccagg cttttctgca ataccgcctc tgaccgggtc agtgcctgac gtgctgccag
     3241 cggtttccgg atatgctcca tcgccagcat cgtgtcttca tagccctgct gacgccaggc
     3301 gtcggtatgt gccgatgtaa aactgagcag accgccgctg ttgccaccat cacctgcata
     3361 tttcagcctt ttccggggac ggatctcaag gattgtggtg tccggaaaag cctggcgatc
     3421 ccataaagaa ccgtcactca gatgcgtcac aatcaccata ttgcatccgg catcgaccag
     3481 aggtgtcaca ggggtatttc cctgcatatt tcgccatcct cccataccac catcaccgaa
     3541 cattgtcccc tgaacctcac ggggacggaa cagcaggggc agcgcggctg acgcaagcag
     3601 agcctctttc tgctgtccgc ggggcaggct ctggatatgc tgaaaaacgg cgtttttcgt
     3661 ggttccgaca cccagttcag cacgaatgca gtcaataata tcctgcatgc ccccttctgt
     3721 ggggtacagc gacacataca gcggtagccc gtctgccaga gcatcagtat caagataatg
     3781 atccatcagc gctgtcaggg gctcatctga caacaacggc tgagccatca gattgtcaaa
     3841 cccgttgatt gtcgatatat ggcgaagaag cgtcgtaagc agtgctcctg cacgtccggg
     3901 gatctggcag aggttcattg cctggaacaa ttttttcagc aatgaaaagt aaaccaatct
     3961 gtttaccgac agcacctgat tattccccag atgatcccag agcgcctcca ggcgtacggc
     4021 agcttctgac agatcgggag aggccacgat aatggcacca ttgaatgcgc caatgctggc
     4081 ccctgaaacc atgctgatct gtgtaccaca ctctgccagt gccttaacca ctcccgcctg
     4141 ataagcgccc accgccccgc caccggacag caccagcccc gttttcattt ctgtactcat
     4201 gcagccccct tctgaaatat ttcatcgacc atactttcag agaggcgttc tgcagagcag
     4261 aggcgaggca tgcgaaccgg taagtgttct gcagcctgcg tggttgacca gatcaccgga
     4321 tgctgctctt cactgcacca gtctcccagc cagttaatcg cgtcatgcca ctcgttatct
     4381 gcctgctccc ggccctgacc accaagccag tccagagtgt tcagacgcac ggttgcacta
     4441 ccgccactct cctgtgccat ctgcgttaat gctttatgtc tgagaatatc cagtagctgg
     4501 ttaacctggc ctgtttcgct ctgacgtatc acatcaccaa acgcgcccca gcgaagctct
     4561 tcaagtgcca cataacaacg tccggcaggg gaaaatgacg catatcgccc ggcgctccac
     4621 catgagaata tctgctcaag atgtaactgc gcccgctgaa cctggtcaac acggtggagt
     4681 ttttcttcaa gatgattcag tttatggtga acctgatcgg ccagggtgag caactgctcc
     4741 cgcgtatctg cggaataatg cgccagcctg gctgtatcac tgaccagtga actgaccctg
     4801 tcgtttacct gggtaatcgc gtagtttgtg gtggcaagtg acgttgtcat ctccgtcagc
     4861 cagcgcaggg acgcctcaac gccctgtgca agcgacgcat tgatggcatt ctgccgtgca
     4921 gcgccttcgc cggtcagccc ctcttttaaa cgccggaaga acgtgcgctc tccggccgtg
     4981 cggatatgct cctgtgcaac atcgattccg tttgcgaaat caaccacaaa tttttcagga
     5041 agacaggtga gtacctgaca tacccggtta tcagcaattt gttgaataaa tggtgaaatc
     5101 acagcattgt ctccagctct tccctcagcg ccttactgtc agtaatgagc tcaggaaccc
     5161 tttcatttaa tgcctgaagt cgcccggtaa gtcgttcctg cgcctgctga tcgcgtttat
     5221 gatcttcaga gctctgaatc agcgtgttac gcagttgttc aactttctcc ctgaatgcgc
     5281 agaaaaaggc atcgatttcc tggcggacgg gctggttaat atcctgctca atggatgcct
     5341 gcagctcccc gaaatatgcc cgggtcagtg acataacttc ctctctgacc ttgttgatat
     5401 tgatcacgct gcgactcaca tcctcgtcat agttttccca gcccaggtca ctggtgccaa
     5461 accatcgaca aacggttccc catacgccac tctgccgacg gcgacgggtg acggtctccg
     5521 ttctttcctc cataagcgca ctcagattta tttttaccgc gagccgggtc tgtaactggc
     5581 tgactgccgg aaaactgatt tttacggtaa agccctcatc ctccaggcgg gcattgatgc
     5641 gaccggcaat gttttctgtg gcgtacaggg ccgtgccacg aaaacctgtt tcaatcccgc
     5701 tgacgatttt ctccagctca ggccggaact gtgcttcagc ctcacggtgc aggctggtca
     5761 cggtcgattc gatttgcgtc atcagttcaa gggcttccct gcgatcactg aattttattt
     5821 cggggctgtc cggggcaaaa tctcgtttcc tgtaatcctc ccggccctgg ttgttgatac
     5881 cggaccattg agaaattttc ccccataatc cggactgaga ccttcgttgt tctgcgtctt
     5941 cttcctccag catttgctgt tctttgcgtt taccgcttct gaaatagtca ttcagctcct
     6001 cttccagtga ggtgcagacc cccgtcagta attcccgggt tttagtatcg atctcctcca
     6061 tggccattct gacatcagtg gtcatctgct cctgacagtc cgcgatttcc cggatatccg
     6121 caagcaggct ggtgatatgc gactgcagtg actgaatgct ttgctgtagc ccctgatggc
     6181 gtaacaacag gtattcactg atattttctg cattctgcat cagttttgcg gcggcagagt
     6241 caaccgccag tgccgcagct ctggaatgtg agctctgtat gacttccgtt atcagttgat
     6301 cgataagtga gccttcccac aggtctgtcg ccccttcagt tgccagttca ctgtctttac
     6361 agacgtattc ttttttcatg caaccgaagg cacctctgat aaaatcatcg acccaggctt
     6421 catcaacagg aagggttccg tttttccgta actcatgaag cgcacggtta gccaggtatg
     6481 cctggcgtga ggatccggga taaacgcggg aggcgggcag cacatcgctg ttcagcattg
     6541 ccggaacttt ctggcgtacg gcatctgccc catcgccatt gcggtctttc tcatcaaatt
     6601 tattgaccag tacaaacagg cggccggctg atacgtcagc aatggcatta agctctttac
     6661 ggacgtcttc atccgctttt gagttcatct gggtgtaatc catcacagcc agaaccgcag
     6721 aggctttctg cagttgatcc cgcatcatca cttccatctg cggttgtccg gcctcattag
     6781 ggccgggggt atccagcagt gtgagtgttc cctggcatgc atccatcccc accagatggc
     6841 tgaattccac gtcgatcacc ggcagtttct gcacttctgc gtattcatca aaaggaaatt
     6901 cagtccccat tgccgcagca agacgaacca gatcgtttaa cgatgccagt ccggtaaaga
     6961 tttcctcctc cccgtggtat tcatttttga gccagccatc atccgtcaga atatccagca
     7021 gttcgcgggt atccccggtt tgctgcaggg tctgtgcgac ctgctgtcct gccggggtgg
     7081 cgagtttttc ctgcagtgtg attaataaat tgcggacagg ctgaatatgt tccagatgga
     7141 gaaccggctc agtttttccg ggaacgtggc ggatgagcgt cggtacagag gtcatggggc
     7201 ggttacggtt aggcagaatt tcctgcccca caatggcgtt gatggtggtt gatttgcctg
     7261 ctttcatcgt gccgacaaca gccagcacca tctccctgcg ggcggttttg atttgttcgc
     7321 cctccagctc ctcaattctt ttcagtgctt tctgtttatc aaaaagcagt ctgttttcgt
     7381 tcttactgtc agataacaca tctggctcct caaccatttg ccggagcaga ttaatgttca
     7441 gttgcaaaag tcggtcggct tcatcacaaa gcagggcgat gttcttttcg tgcattattt
     7501 aaccttccta agacgcattt tcatgacaac cacggaggag gtcatttact acaaacgatc
     7561 gtttataacg atcgatatga tagtaacgat cgatgcattc tattaacttg agaaacacaa
     7621 cgcaagggga caacccgggt atggctgcgt ttgcatagtg ttttcatgga gttaaaaatc
     7681 tgtaacaaca gcctggtaca tcaccaccgg gttcagaaga aaatccagtt ccataccgcg
     7741 cgggcaacag agaccaccga gtcacggacg gcgcgcagaa ccgtgcgtgc aacagaggca
     7801 atgcagacgc tctccgccgt gtcaaatatc cggtccaccg caccggtaaa ctgttcacgg
     7861 gcctgagacc ggacagactc cgtgcgcagc tcgtcctgca ggcgggtcat caggggactg
     7921 gcggcatggt cgggaagtgc tgtcatgagc gcactgacca gcgtatccag ttcccagccg
     7981 gtgcgggccg atacggcaac aacccgatgt acgggccgga acagacggaa taccgcctcc
     8041 gttttttcgc gaatgttctg tgcctctgcg ggagaaggct gaataccggc catatcccat
     8101 tcatggcagg gctccgtttt atcggcctgc atcaccacaa acagtacccg ctgatgtccc
     8161 cggtgcagga tgtgtcgcca gaaatactca tccacagaca gggcacggtc atcggcttta
     8221 atcagccaca gtaccaggtc cagttcgagc agaatgtcac ggtacagggc ttcatactct
     8281 gcatccctgt cccggctctc gcccaccccg ggcaggtcag tgataaccat gctgtgacca
     8341 tggccattca gacggaagcg ctgcacttcc cgggtgccgg cgtgaacatc actgaccggg
     8401 gtgacctccc cctgaaacag cgcattacag agtgaggatt tacgggcccg cttttaccca
     8461 taatgccagg cacgggttcg tgactggtga gtttgcgcag atgttccagg atgtgacggg
     8521 aaagtgagta aggcagggag gagagcggtt tttcaattgc ctcaatggca tcagacggat
     8581 tcatacatgt attcccggtg aaaaaagaca aaaccccgcg caccggaaag gtggcggggg
     8641 attcacggaa ataatatctg tctgaaatta tctggaatcg atttggctgt tctgcctggt
     8701 tgccaccaaa tcatggtacg cctgctcaat catttcattc agcagttttt ttgggaggac
     8761 accacgactt cgggcaatac tttcaagctg tttgtggatt tttccggaca gtttcagagg
     8821 gacggaacca tcagcacgtt catcacgcct tttttgttgc tcccgggcac ttttcagctc
     8881 atcaagaaga atcgctttat gctgaatcct gggggcctgg aaggagacct gcgtaaactt
     8941 cgctctgttc cgtctgggat tactttccag taaaaactgt acctgttgct cattccagcc
     9001 ctcccagtta tcaaacgtgg cgcaggcaaa ccagtatttc tgctccgggg taaggggatt
     9061 cagcggggtt cccacacacc ggacctgcat ggcgttccat aaccagtcac actgttcact
     9121 gtccctgctg tccacccacg aaaaggggga ggggtaatca ttgtttatgc tggcccattc
     9181 agagaatact gagttgataa tcgtcctcgt agcctctggt ccggatttca gcaggtaact
     9241 ggagcagaac catataattt cacggtagat tttatccgga tgcacggtgc gcatcggctt
     9301 ttctctggga ccggcaatct tcggttgcga tggaaacccc gtggcaaacc gcagatgttc
     9361 cgggggcatt cctgaacgtt tttcaggaat gggtgtgagt cctgcgtttc tggtcttttc
     9421 cgcttgtccg gtattgcctc cggccggagt gttgtcggga gtatcttccg gaggcgaggt
     9481 gttttcatta gttgggggaa caacagcaga actgtccatc tccggaatgg gttgaggggc
     9541 ataatcactg tggtagccag gggaaagcgt taagtcccga agggtgacat caggttccgg
     9601 gcagtgagtg ccaccgggag tgaacgggag ttgttgcttt tgggagaaaa atgtattgtg
     9661 aatgcgggta tacagctgga acagaaaaaa ataagatgcc cgtggttctt tttttaacca
     9721 ctgtgtatat tcctctatgg caccgagctg ttgtttgtgc cgttttacag catcgatata
     9781 cggacagctg gtgcagatat catccagttc ctttcccaca atacacctca cctgcttttc
     9841 tcacatttgc agattttaaa aaagcaaaca aaaacctccg tacatgatgt acagaacaat
     9901 ctaccaggta gtggcgtcag aaaacctccg ggccgcctgc actttccgga atgcgccggt
     9961 tatgaaaaac cggaaattca gtctctgttg taagatgtac cctctgatac tacgttttct
    10021 ctgtgtattt aactcactgt atttattgtc tttttaagct tgactgatat tctccggtca
    10081 tagtgtgccg gatacacatc ccgtaaactt ctcattttta tataaaaata cctgcactct
    10141 cttcagcgca tctgtctcct ttaagtaaaa aatgttttta cgtattgctg taaattcatt
    10201 ttaaatcagt atattacctt gatattgctg tctcctggtt tgatgcgtaa tcgttctgcc
    10261 tttctggatg attctggtgc ttccgggtgc attctcctct gcacatgcaa cagttcgtca
    10321 tcgccacgct cccaaaaagc atataaaaac gaatcgaatt tgatattttt ttcaatcgtt
    10381 tttcatagga atttcgtagg gtattctccg ctataacctc catatttgct gtctttttct
    10441 tcataaatcg tatgcaatgt agcctgtctg tcaagacctc ttctctgctg ttgaggagac
    10501 gatctcattt ttggtctttt ccgggagaga ggctgtcaga tgagcgagcc ggatatactg
    10561 tcagaggtac accccgtagc agacctgtgc tcccatttcc gcgatccgga accaacaaca
    10621 ccctacggtt aataccattt gaagcgtcag gtactgcagg aagttccccc ctgcgcggac
    10681 atcggttcct gccgacatct cacaatacgg ccagactgtc atgcagtaac acccgcatgc
    10741 ggtctgcggt tttaagcgca ctctcccgtt ttcagtgcac cgataatgcg tcatagtaag
    10801 tctgggggaa gttacggaat gcctgttaag tggtgccgtg ggtggagaca gcttactttt
    10861 ctacagcaac tgcagtcatt caggatgatc aggagatatt ctgtcaatgt cacgatcctg
    10921 ccattttcgt acccgctaag atacttccgt tactgatgct gtccgctttt caccatttca
    10981 tcctcactga caggcgttgc gttttgggtc atcaccacag ctttacgttt ctcttttaac
    11041 cggtaacgct ctcctttgat attcagcgtg gttgagtgat gcagcagtca atccaggagc
    11101 gctgttgtcc ggcaaccacc atatcaactt cttcccgggt gtggcggaga ggtggtatcc
    11161 tggctgagtt tcgaagcgaa ccgttctttt tgacgggcgc attttacgtc cgggctgaat
    11221 gtagtaacgc ggcatggaac gtcggcccgt ataccattgc cttaatctcc gcaaagataa
    11281 cctcgtcatt ccggacattc tctgccaggc atatgtcgat gtaatccata aacgatttca
    11341 gcttacccct tttgttgtca cgaacggtgc aatagtgagc cacacccaac gcctgaaatc
    11401 agatccaggg ggtaatctgc tctcctgatt caggagagct tatggtcact tttgagacag
    11461 ttatggaaat taaaatcctg cacaagcagg gaatgagtag ccgggcgatt gccagagaac
    11521 tggggatctc ccgcaatacc gttaaacgtt atttgcaggc aaaatctgag ccgccaaaat
    11581 atacgccgcg acctgctgtt gcttcactcc tggatgaata ccgggattat attcgtcaac
    11641 gcatcgccga tgctcatcct tacaaaatcc cggcaacggt aatcgctcgc gagatcagag
    11701 accagggata tcgtggcgga atgaccattc tcagggcatt cattcgttct ctctcggttc
    11761 ctcaggagca ggagcctgcc gttcggttcg aaactgaacc cggacgacag atgcaggttg
    11821 actggggcac tatgcgtaat ggtcgctcac cgcttcacgt gttcgttgct gttctcggat
    11881 acagccgaat gctgtacatc gaattcactg acaatatgcg ttatgacacg ctggagacct
    11941 gccatcgtaa tgcgttccgc ttctttggtg gtgtgccgcg cgaagtgttg tatgacaata
    12001 tgaaaactgt ggttctgcaa cgtgacgcat atcagaccgg tcagcaccgg ttccatcctt
    12061 cgctgtggca gttcggcaag gagatgggct tctctccccg actgtgtcgc cccttcaggg
    12121 cacagactaa aggtaaggtg gaacggatgg tgcagtacac ccgtaacagt ttttacatcc
    12181 cactaatgac tcgcctgcgc ccgatgggga tcactgtcga tgttgaaaca gccaaccgcc
    12241 acggtctgcg ctggctgcac gatgtcgcta accaacgaaa gcatgaaaca atccaggcac
    12301 gtccctgcga tcgctggctc gaagagcagc agtccatgct ggcactgcct ccggagaaaa
    12361 aagagtatga cgtgcatctt gatgaaaatc tggtgaactt cgacaaacac cccctgcatc
    12421 atccactctc catctacgac tcattctgca gaggagtggc gtgatgatgg aactgcaaca
    12481 tcaacgactg atggtgctcg ccgggcagtt gcaactggaa agccttataa gcgcagcgcc
    12541 tgcgctgtca caacaggcag tagaccagga atggagttat atggacttcc tggagcatct
    12601 gcttcatgaa gaaaaactgg cacgtcatca acgtaaacag gcgatgtata cccgaatggc
    12661 agccttcccg gcggtgaaaa cgttcgaaga gtatgacttc acattcgcca ccggagcacc
    12721 gcagaagcaa ctccagtcgt tacgctcact cagcttcata gaacgtaatg aaaatatcgt
    12781 attactgggg ccatcaggtg tggggaaaac ccatctggca atagcgatgg gctatgaagc
    12841 agtccgtgca ggtatcaaag ttcgcttcac aacagcagca gatctgttac ttcagttatc
    12901 tacggcacaa cgtcagggcc gttataaaac gacgcttcag cgtggagtaa tggccccccg
    12961 cctgctcatc attgatgaaa taggctatct gccgttcagt cagaaagaag caaagctgtt
    13021 cttccaggtc atcgctaaac gttacgaaaa gagcgcaatg atcctgacat ccaatctgcc
    13081 gttcgggcag tgggatcaaa cgttcgccgg tgatgcagca ctgacctcag cgatgctgga
    13141 ccgtatctta ccccactcac atgtcgttca aatcaaagga gaaagctatc gactcagaca
    13201 gaaacgaaag gccggggtta tagcagaagc taatcctgag taaaacggtg gatcaatatt
    13261 gggccgttgg tggagatata agtggatcac ttttcatccg tcgttgacat ttgtggccag
    13321 tctttctggc tggcggttca ggggatgttt tctggttatc gtgtaccaca aagcagggat
    13381 attgccccga tagtcacatt tcagattgat cgcggtctga agatgtggca ctgaggtaac
    13441 gtgctggtgt cactggtatt gctgaagtta tggtttttcg gggtcaggtg agcctgttgt
    13501 gtgtatgctt tttgttcagg tcagaggggg actgtgtgga cagcggcttt tgtctccggg
    13561 cattcacgcc tgaacgatga atgcgatttt cagcaatatt tgtctttgtg acactctctg
    13621 gttgagaagc taatgcgcgc ccctgtttcc acagagaatg aggcttgcca tcagccgaaa
    13681 catcagtatt ccacgccata cagacggcgc ctgaccatgt gctgatgcag gtaaaatgtt
    13741 tcactacaac tgttcgagtt gctatgcaac gaaacagcga ttctcacgat ctttaactgc
    13801 aacgtttttc cgcctgaaag ctgactgcct cctgctgagg tgggaggcta tgattcagtg
    13861 cgtttatagt ctccggggta tgcatgtacc ggagcatacc atttctggtg gataacaagc
    13921 cggcacattc agactgcagt gaagatggag gcacctggtt gtgaagaacg tttctgcccg
    13981 tggctgcttc gcatcatcaa tggtattcat acccgctcag aaatgaccgg gtgctgaagc
    14041 cctccgttat cgcgcagtat aatgacgtat atgatctgtg gacgagtgag cggcgtgcct
    14101 gatgtacgcc gctattactg tattttacca cagggctggt tttctgctgc cagccctgtg
    14161 gttctcagac atcaactgtg agcggcatca accgatgtac ggtatgccat aagcacgtac
    14221 tgatccatca gatttgtcag tggttcactc tgaccctgac gtgcaatgat ccattgctcc
    14281 agatcttttt ctgatttgtg tttcaggttt ttcgtccagt cgtcaaggct gtttccggtc
    14341 attaagtcaa gccagcagag ccagaccagt ttgagacgta actccgtgcc gccaaactga
    14401 cggaagaggc tgatcagttt gtttgccaga gaatgttgct tcaggcgctc acattcagac
    14461 agcaggatcc cttccagcat cggatgatga accagcaggt gttcgctggt gcataaattc
    14521 accaccagat catcatccag ggacggggag ctccgtttgt ccggaccata aatcagccgg
    14581 tgcagactct ggggaacgat ggcaatctcc ggtttttcgc cattgaatga cacccacccg
    14641 ggcgtcagat tatggaaata gtagatattc ggatgacaca cgccccatga tacggcgtgc
    14701 cgggtgaagc cggtcagcca tttctggtag ttttcatgga gcagctcgta acgggtctga
    14761 tactgttgtt tcattttcat attcctcacg ggggataaca ggcagcagag cgccgccggc
    14821 aggccggaga ttgcgtctgc tgtgggcgaa gggttagtgg ttaaaaatta cggacgggac
    14881 tgtgcaatac gcgcctgcag ccaggcttcc acttcacttt tcagccagcg ggagctgcgc
    14941 cccattttga tgggcgcagg aaagccccca tctttgatga gtttgtcaaa ccacttatcg
    15001 gttaggccgg tcagttgagt gataaacgcc atgtcgacca tctggtcatc catcagcgaa
    15061 actggggtag ccatgagaat gttcctccgg atgttgttaa accagccggt gtggtcatga
    15121 aaacagcgcg ccaccttcac cggcataaca accggggaga aacgtaaaaa ataatcggga
    15181 atgcggctgt ccggagataa acggggggat tgcgatggca gagccgtagc ggaatcccgg
    15241 aggggggtgt tgcgaaaaga tgcttccgca cgcacgcgcg ataaagaggg gatagttttc
    15301 gtgaggacag ggagagaagc aggcgttctg ataattgcag agttgttttc ggaggtggtt
    15361 acagtgagtc agcccgttcc tggcgagcag gagactgata tcaccgatgg gataaggttg
    15421 tctgattggt attataaata taagaagtca tcagagagta acgtaaagga tttgccagaa
    15481 taacctaaga gagtaaatct ctccggtaac agagcgctgt gaagcattct gtatcagagt
    15541 gcagatacat gaacgctgat gcgtaaaatc agcagtgaca cgccagctcc ccctatgccc
    15601 attcctgtat aagacatgaa ctgagtgtat taatgcttct gccctgagac tgagccggtg
    15661 agtgaggggc tgagaaatcc ctcttgacac agctctgacc agaaatactt ccccggttgt
    15721 tgcggtgcgt ccggatcccc gataacggaa cactaaggct gtattgcggg acaccgggta
    15781 agtagcagcc cgtaaggcgt tctgtcaacg ccagaaaaaa tgatttccca cacgcgttat
    15841 agactcactc ctgtggacct ggaagcccgt aactctgcgg ttgcccactg actgacggaa
    15901 ctgaccgcaa attttacgag tgcgtgctgg gcttcagtct ggtcacctga gcgttcggta
    15961 acggaggcgc gggcggtaat aggctgattt tcaggtatta ccggcttaca gcgtgtggtt
    16021 gatattgagg ggctgtgagt ttcgcgtatt tgtcagaaac ccagacgagt tttcctgtat
    16081 gggacgaaat aaggcagcgg caatacctgg aaaaatttaa tatggtatga aggagaacct
    16141 gtcggttacg cttaatatac ccggtacact gtcagctcag gggatacatg aaccgttatc
    16201 tcaccagcta cacagtatat acacactgac gctgacagta gtcagcagga ccacaataat
    16261 cagtgccagc agtatggtaa cgatacggtc tgtattccgg taatagccga aggggtcgac
    16321 agaaccacaa tacgggcaac acactgtatt atgagtaatc gcgtttccac agtccctgca
    16381 cttctttttg cgtatcacca tcactccctc ctcacagcct tacccgtaac cggtttttta
    16441 cattaaaaaa acaacgctga aaattcaacc gtcagtccgg agacgaccgt tcgggttatc
    16501 acagagtgcc tgagacagtg tcctgccgga ggtcacttca gggactctgc gcatttttta
    16561 cgacgtggct attccgtatg aaccatacgg agatttaacc atgacctaca aatacaaccc
    16621 cttctggcag caacgtattc gtgagacggt gcggcacgca ctgaatgttc atccccgcct
    16681 gacggcattg cgggttgacc tgcgtttccc ggatgtaccg gcagcaacgg acgcagctgt
    16741 gatatcccgc ttcatcaatg ccctgaaagc ccgaatcgac gcttaccaga aacgtaagca
    16801 tcgggaaggt aaacgcgtgc atcccacaac cctgcattac gtctgggccc gggagtttgg
    16861 ggagtgcaaa ggtaaaaaac actatcacct gatgctgctg gttaaccggg atacctggtg
    16921 tcgtgccggt gattaccgtg ctccgggatc actggccggg atgattaaac aggcgtggtg
    16981 cagtgccctg ggagtggatg tcgggtgcca tgccacgctg gtgcattttc cggcctggcc
    17041 ggcggtgtgg ctggaacgcg atgatgacac tggctttcag caggtgctgg aacgtgctga
    17101 ctatctggcg aaggaacata ccaaagctca ctgcaccggt gagcgcaatt ttggctgtag
    17161 ccggagttga gcacgactgg cgcgccaata cccggcaaac caaaagtatg ggttgttgtc
    17221 tggcggcaac gatgtatcca ctcgcccact gactgttttt tacgtcagtg ttccattgtg
    17281 tgacaaccac agtgctgtaa cagcaaccag cctgctttac ccaaactcca gtccagattt
    17341 taactgaacc gccattcaca ccctgaccac gctgcccgta ccgggacggc tgttgcctgc
    17401 gtgtcgtctg gcggctgagg aatatgacta tgtacgcaaa atcctttatc gctcttgatg
    17461 gcaacggacg tctgacgggc gcccgtactg cacaggccgc accttatgct aactacacct
    17521 gccacttgtg tggcagtgca ctcagatacc atccgcaata cgacactgaa cttccctggt
    17581 ttgaacacac tgacgacagg ctgacagagc acggtcaaca gtgcccttat gtcaggccgg
    17641 agcgcagaga aatacagttg attaaacgtc tgcagcaatt cgtactggat gccttacccg
    17701 tggtgcgtaa agccagctgg cactgcagac aatgtcacca cgattattat ggggagcggt
    17761 actgcacaca ctgccagacc ggaggattca gtattccccg gacaactcag gaggaaatat
    17821 gcgaattctg aactgttata tggcgaatga cagcaaaggc cattttgtta cggcgaaaga
    17881 agcagcgaag cacaaccgcc aggacgtttt gtgctgtgtg tcctgtggat gcccgttaac
    17941 acttcagcgg ggcaatgacg gacaaccacc gtggtttgaa catgaccaga tgactgtcgc
    18001 tgagaaaatc ctgctgcgat gcacctggct tgacccggca gagaaagagg cccgtcgttt
    18061 gcatctgcag ggtatgacgg ttccggatta tacggtgaag gtgagaaagt ggttttgtgt
    18121 gatgtgtgac gaaaattatg agggggaaaa gtgctgcccg agttgtggta ccggggtata
    18181 cagcagggag ggggggcagg agggcaactg gaaggatagg aactgagcgg ttcagtcgcg
    18241 gaaatcagtt gcagagctgt aatgatatct ccgggagtgc tgcgttggta ggggcatccc
    18301 gggatagaga aattttagca ctttgccctg aatgattgta gacgtcccga gtactcgtac
    18361 cggtctgagt tattacagtt agatattcac tttttctccc gcatacttca catctgtcaa
    18421 cgacggatga aaagtggttc ttccgcaacc tgggtggaag aaaatggatg aaactttctg
    18481 gcgaacaagg atctaagctg ttttaagtta tgggcaacgc aatgcactct cttaagacac
    18541 ttctacagtt accttgcgga tggcgatgca gtcgacaaat tattagctct gacggtataa
    18601 ccctccatct ccacggaaaa cgcaaaacag cacaatgtcc tgaatgcttt aagcgtagcg
    18661 actctgttca tagttgtcgt cggcgccgga tacagcatct accctgctca gggcagacgc
    18721 tatggcttgt attttccgtc cgccactggt actgccgtaa cccggcttgt tcacgtaaaa
    18781 tttttgccga gtcgcttgct cccttcgcca gttcacacca gcagtcttca caggcgttac
    18841 aaaattaaca acgtcaactg ggattaatag ctggaggtga ggctggaaaa cgggctgcaa
    18901 cggcagtggg tctccgttgc agtgctgata ctcttcttcg caggcttatc aataccccgg
    18961 agacgaaaca gtcaggcgcg cctcatgtcg gtattgatga gtgggcgtgg catcggggcc
    19021 actgctgcgg tatgttaata gtcaatcctg atactcaccg tcccctcgtc ctgcttcccg
    19081 gccgtgatca gcgtacgctg gcgacctggt tcagaaaata tccggaaata caggttgtct
    19141 cgcgtgatcg cagtggagtc tatgcgacag cagcacgtga aggtgcacct caggccagac
    19201 aggtggccga tcgatggcac ctgctaaaaa atattggtga tgagcctgaa cgaatgatgt
    19261 acagatatat gcctctgata cgtcttgttg tcagagagtt atcactgaag aaatcacctg
    19321 agccagaaat atctgtgcct gtagcatcgc tccgtcgtct ggaacgcctt aaacagcaca
    19381 tccgcaaaaa acggcatcag cgttggacag aggttatggc cctgcataac aagggatgta
    19441 gtttcaggga aatatcccgt attacaggcc tgtcgcgagt gacagtcagt cgctgggtgg
    19501 gttcaggaac attccctgaa atgtcaacta ggcctccaaa gcgagggctt ctggacccat
    19561 ggagggagtg gttaaaagag caacgagaat gtggtaatta taactccggc cggatatggc
    19621 gggaaatggt ggccaggggg gttacaggca gtgaaaccat cgtcagggat gctgttgcca
    19681 aatggcataa aggctggatc ccaccggtta ctactgccgc aagacttcct tcagtgtccc
    19741 gggtaagccg ctggttgatg ccctggagaa taatcagggg tgaagaaaat tatgcgttcc
    19801 gatttattag tctgatgtgt gaaaaagaac cggagttgaa aatagcgcag caactggtac
    19861 tcgagttcta ccgtattctg aaaacctaaa ataaatcaca gctaagcagc tggttcactc
    19921 gggtccacga aagcggctca gcagaacttc ggtgcgtagc tgcggggatg gaagctgatg
    19981 ctgcggctat atgtgaggca atcagcagtc gctggagtac tggtgttgtc gaaggtcatg
    20041 taaatcgcct gaaggtgctg atacgccaga tgtatggtcg agccggactt gaactactta
    20101 ggcggagggt aatgagtcca ctggcatgaa aatcttcacc taggttgagg aagagccact
    20161 tttgcactgt tcgtgacagt atggccttta tgtactcact ttgttaccgg tagctggatc
    20221 atcactaccg tgccgcaaat ggtggtgaac agcatcaatt gtggaatgaa tgttgccgaa
    20281 gcgaccaatg cgcctcgttt ccaccatcag tggttgccgg acgagctgcg tgttgaaaag
    20341 ggtttagtcc ggatacgctc aagctgctgg aagcaaaagg tcagaaagtg gcgctgaatg
    20401 aggcgatggg cagcacgcaa agcattatgg ttgggtcgga tggtgagttg tacggcgcat
    20461 ccgactcgcg cttggtggat gatttaacgg cagggtatta attgacatcc cccggcgcaa
    20521 tgtgccgggg gataatggtt ttatgcggtc aataatcgtc cgggattatc gatacagagt
    20581 tttttgagga tcgttttatc gacgccgcgc tccgccagat aggccagaaa aacatctgga
    20641 acaaatcccc agccattacc gccattttta gcccacattt gtttaaggaa gacatcgtgg
    20701 ctgagaacaa gctgatcggc gtatcccaac tcaatgagat gagcgacggc atcggcagtc
    20761 tcctgcaccc ctggcgctat tccctctttc gggaaggtaa tgtctaggcc aatcatgtcg
    20821 aattccagcc agacaccttt atcaagcatt ttccgctgat acgccacgtc ttttcctgac
    20881 ggatccgagt gtgcgagaga gactttattt ggcgagacgc ccatttcacc taacacaatg
    20941 tcgagtactt catcaccgcg acgaagccag cccggcatgt gaatattcat cgccacatga
    21001 ggattgttaa tctgtgccag cgaggcagcc cgcaagctgt tatgctcggc ttcggtaaat
    21061 gtcggtgaga cacctatttc accgatcatt ccggcacgaa tatccgtatc gccaatccct
    21121 tgattcaatt ctttatcgat cgttgtcgct agttcatcaa ccgttttatg aattctctgg
    21181 ctttcaaatt tttccaggta gggaccggag gaagcaacaa tattcagacc tgtttttaat
    21241 gcgacttctc gtaatgcctg cgcatctcgt ccgatagact cagaccctgt ggcatcaaca
    21301 atggtgcgac caccgagcga gataaagtta ttaatttcga agatcacatc ttcaataggt
    21361 ttgcggtcca tattatcagc gcagcaataa ggatcgtgtt ttaatgccca ctggatttct
    21421 gccgtgactt ttttatcaac aagctgttgt gaaaaaggat agcaaggagc atccacaaca
    21481 gaggaaagat cgttgaacag atgttcatga ggaagtgtta gccccatatc ttcacgggcg
    21541 acggggcccg tcacagtttg tagataatct ttcatgatta tacctccatt ttcttcattg
    21601 ttttcgaggc tctgtattcc ggaatagtgg taacaattgc accgaccagt gcaaacagtg
    21661 ttccgatgat cgtgaccaga taaacggtat tgcccagcga tggaattaat acgtcaatca
    21721 atactgatcc cagtaactgg cccgccgttg aagcaacccc cagcatcagt aaccccagac
    21781 ccctgaccaa aatggccatt aaaccgatag acattagtcc aagcgggccg ccaagataca
    21841 tccaccagac atctggtaat tgaacagtga cgtgccctaa tgcgacacga atagctagcg
    21901 ctgtgcctaa aacacaaaat ccaacgatga aattccaggt gattgaaacc agcatggatc
    21961 ccgtagcttc agctactttt gcatttccag cgggctgcca tcctgcaagc aaaccagcta
    22021 agaacggaag aatggcaagt aaaatgaaag aggtagaatg ccactgcggt gacacaacaa
    22081 aaatcgtagc aataaccgca aataatgcac cgatgatgcg ataaggggta aagtattttt
    22141 tctcgtcgac accgatacca aagcgatcgc aaagtaaacc agacagcaat agcgcggaga
    22201 tcagtgcggt ctgaaacgtt gcgaccccga gtgcgctggc tgatgcgcct tcagaaaata
    22261 ccaccatcgc tccacagaga ccggcaaacc agttccagag aggaactttt cggtttttaa
    22321 tcagagaagg aattgccgca aattgttgcc ggatttcttt tcgcgccata ataataaaaa
    22381 acatcacgac taaaccactg gcaaaggaga taactgcgca tgcattaccg tcctgtaacc
    22441 agtgacctaa ttgaccattc accgctgatt gcatagggga gagcataccc gcaagaatcg
    22501 tggcaagcac ccataaggga gttgagtact tattcttttt catacatcaa tccttctatt
    22561 atagtaaatg gagtaactgg tgttacccca ttattattat tatcttgcaa tatgagtcag
    22621 tatatttacc cacaacgcgg tatagaacgg ccaggacata aactgctgtg taccccagtg
    22681 cggtgaacag tcactcataa agcaggctat tttcccgttg tgatagttac caaagaccag
    22741 taatggatcg ttgtttattg ttaataccac ctcagcattt tctttagcga tcgcccggtt
    22801 ataacctagg aaaaaaggat attcagagaa ccctttaata accggatggt caggttgtga
    22861 tggctgtgca ataacaccct ctggtttttc gacacgatcg tcaccatcta acatcgtaac
    22921 cgggagcaca tcagccagaa ctgtattttt ataattggct tttgcttcaa ttcccatgaa
    22981 tgagagatag ccgccaatca tcaataaccc accaccgtta ttcacatatt ctttaatcag
    23041 ttcgagagcg tttggtttta tgcgaagctg ataaaaagta tcattttgta gcaggaaagt
    23101 attactacca atatcactaa taacgatggc atcatattgt tctaactgtg ccacatcttc
    23161 agggaaggca atttgtaccg tatgtgccgg catataggtg acatctacct gactattttt
    23221 cagacattgg agtaaccagg tcgcaccttc ttcatattta cttgaggtaa aactgtcata
    23281 tccttttgaa tgaatcatat gaatatgcca ggattctcca ataaagagca cctttagtga
    23341 ttttttggtg ttattcattc tctgtccctt cttaatgcgt aaaaatagtt tgctgataat
    23401 gtatactctg aattcgatgt atcacagatt catgttcagg catgtcggaa gcattgcttg
    23461 tctccaccgc tagggatgca aaggcgctgg cataacacag tgctgattcc agtgattttc
    23521 ctttcgcaag tcctgatgcc agagcgccgt taaaagcatc cccggctcct gccgtatttt
    23581 taacgaccgc tggaaacgct ggcgaatgaa tgaatttttt gccatcaaat gcgagcgagc
    23641 ccttgctacc gagcgtgata acggtgtttt ttaccccttt attgtggata gcttctgcag
    23701 ctcgtttagc tgattcaaga tcgtgtacgt ctatgccgga cagtaaacca gcttctgttt
    23761 cattgggggt gatataatca acatcctgaa taagttcgtt gacgatatca ttatagggtg
    23821 ccgggttaat aatgaccggg atactgtttt tttgcgccaa tgtgatcgct tgttgcagag
    23881 cggtataatt tgtttcgagc tgcagaagta tgacatcaga attaataatc gcttctttct
    23941 gaatagttat ttcatcggac gacattgtca tgttggcacc gggatagatc gcaataacat
    24001 tatcgccagt accttcatta acaaggatcg tggcagttcc ggtttgcgtt tctttcgttt
    24061 gataaattat acttttataa atcttagacg aattcataaa gttgatcgca taatcactaa
    24121 agtgatctgt acctactttt gttatgaaat aaacatcagt atcggcaaag cttgctgcca
    24181 gcgcctggtt acaacctttt ccccccggtg aaaatataaa attacttgcc agaagcgatt
    24241 ctccgatagt gggaagcctc ggcaaataac tgatgatatc aacattaaac gaaccaataa
    24301 cgcatacttg acttttcata gttgagtggc ctttttttat tccctaggct gtatcataat
    24361 tttcaagcgc ataagcgatt tcatttttcg caatagtatc aagcgagtct aggacgataa
    24421 aagcaccgcc atgatatcga gtcagatagc caagtctggc aagttcatta agatctgatc
    24481 gaatagtttc tttcgttaca ttgaggctat tggacagatc ggatactttt acagaaccga
    24541 atttactgag tcgtttcaat atttcatgat ggcgttcaaa tttcatgctt cacctcactt
    24601 cagttacgtt aatatctgtc gatgtatatt gatgtgataa tcaccataaa gtggcgggga
    24661 aaagcaaaaa aaatcaaaaa tagccggaga aaaggtaagc gttaatggag aatcatattg
    24721 atgcttattt attggtgaga actacgttcc atggcaggag ttcatcaata cggttggaag
    24781 gttattccgg cagtacgctc aggatatggc gcagatactc ttccggatca atgtcgttca
    24841 gaaggcaagt gccgataagc ccatacaaca gtgcactgcg ctcgccgtcg aagaacataa
    24901 agtttttatt tccgagacag atggcacaaa gggctttttc cgcggcatta tgtctgcctc
    24961 cgcctgaccg tcaacactgt aataacagag tgcgccccac tgattcagta cacagctgaa
    25021 ccattctccc agtctggatt tttggacagc gtggcatttt tctccaccat ccacgcatgc
    25081 agtgagtcca gtaacagttt gctcttcctc tgcctgacca caagatgttc tggttctggc
    25141 atactgaatt tggccacctg agcataggta atatgctcac cttagaacaa cacagatgct
    25201 ccaatgaaaa aaggaaattt cagcgcagag tttaaacgcg aatccactca actagttgtt
    25261 aaccagaact ttacggtggc aggtaccatc caaagctatg gatgtcggtc tttccacaat
    25321 gacaagataa gtcaaacaac tgcgtaatga gcatcagagc aaaacaccaa aagcctctct
    25381 gatgacacca gaacaaatcg aaatacgtga gctgaggaaa aagcggcaac gtattgaaat
    25441 agagaatgaa atattagaaa aggctacggc gctcttgatg tcagactccc taaacagttc
    25501 tcgataatcg agaagctcag agcgcattat ctggtgatag cactctgcca tgtgtgcagg
    25561 attcatcgaa gcagctacag agattggaaa aaccgtcctg aaaaaaagac ggtagacggg
    25621 ctgtattacg tagtcaggta attgagctta atggcggagc aaggaacatc gccacaattg
    25681 caacccggag agactaccag acgggacgca agcttgctgg cagtctcatg aaagaacagg
    25741 ggctggtcag ctgtcagccg ttgaccctcc ggtacaggca tggcagtcat gaacttgtag
    25801 ctatcctaag aacttgaagg gcgcttagct gtgacacagc taaatcaagt atggtgacgt
    25861 gacctatatc tggactggta aacgatgggg atacccgctt acgcgagagc aataagtggc
    25921 tggccaccat tctcgataca aaactctgct gaatagcagc gattttccca gcgtggtgcg
    25981 tcttttgcat tttactggtt ctgagttatc aattatctgt tcactaatga ctactctaaa
    26041 aagttgtatc aatttaagtg atatagggag tccggagatt cacccttttt ggtgatgaag
    26101 ttaacaatac cgccaattgc ctgtgaaccg tacagtacgg aatatggacc tttcactacc
    26161 tcaacacgct ccagcgcaga ctcatctatc aacagtccca caccataatt atctccggcg
    26221 cgctgataag ttacctcctg accatcaatg agaattaaaa cacgggagga tgcttcgcca
    26281 cgaatgcgga tttgtttacg gcctgccaag gagttgtctg ttatctctac tccggggatg
    26341 tcctgcaaat tatcggctat ggaggcattg gtggagttct gcaatgtttg ttggtcaata
    26401 acctgtatag tcgccgggct ttcccaaagg ttgcttgccg aacgattcgt ggtcacgacg
    26461 agcgtctctt cgttgctgat ttttgtttct gaagaagttg cggttgcagt agaaactatc
    26521 ccagaaatgc ataatgacag agtggaaagg atataaattc gacaaggtat attatataat
    26581 atttcatccc tcattaatac aaagtacaaa tgattgctgt aatgataatt attttcattt
    26641 atgttctcat atatctataa ttattgtcat cttcataaat tgtaaatatc aaacattttt
    26701 gaccttaatc atgttttttg atagatattt tacgactgaa catatccgtc gtttcctctg
    26761 actcgtgtca gtcggtctct ggttgtatcc acggaccgca ctcttgacat aagagtgcgg
    26821 tccgtggaaa acggagttga aaaaatggtg tctgaaagaa ggtaccatca ttgtgatgac
    26881 aaatactttg gcgtggataa tgtaattaat tgctgaaatt gaccgtatat gcggtaagac
    26941 tcatatcagt atcaggtccg gttaattgct gatactaata taaacttttt acaaaaggat
    27001 gaatgcagaa ggttactcta atggccagag tgatgacaat gatggtcaga cgttgacctg
    27061 cagaaactgc attttaattg gtctataaag tctgcaagag gaatcagggt cagatcagtg
    27121 agtcttatcg cggcccgaag ctatgactga aagaaggctg gatacagaat tgcaacaatt
    27181 tggcaatgtc agaacacaga agctttgcaa gcaggtgaaa ggttatgtct agcaaaagga
    27241 gtatatcaga atatatctac tgatgtacaa aacacaacaa tagcttcatg atatataaat
    27301 acgtgatgac gagtggtact ccgcatggtt atttaacttc tcagcaccac taatgatcct
    27361 gagcaacttc gtatttgggc cattaccatg gagtagaaag ctgtgtctga gaatgcagaa
    27421 tttgagaaaa gaattcgctt tcttggagag cttctgaaaa tggcacgcta acaacgtttt
    27481 gttaaaaaat gtgaatcact tgccggggct gcattttcta ttcgaggaga atgttgacgt
    27541 agatattaca gaaatctcag cgcatcagga taaactgcta ccttaggtca accaccaaaa
    27601 gaaaatacaa tacgtccagt ttgtatgcct ttaataacac atcttctaaa tgttgaagaa
    27661 ttatcccgcc tgctgaagaa cgttgctctg agtgtgataa acctttttat tcttgatgat
    27721 gtcagcgaga agatggaata tatccccgac tgggtcgtgg ttacccggtt aaacatctgg
    27781 tggcgctaat aaatctggca agtcacattc tgttgaatgc tgtgacagtg ccttaccgag
    27841 agagcgaaat tgtggtgttc tagtgcatag tcgccaccat tccggataat tctattacgt
    27901 tgttttacaa gttcttttac agcgcagatc tgtcgctgac gttgaatcaa tagcctggat
    27961 ttcagaacac aatgcccgtt tgctggttgt tccggcagta gcattaattc attatctgaa
    28021 tgaaatgtgt caatccacag aaaccgctgt caatgacgca ttttgtcgga cgttaacacg
    28081 agaaagtctg gctattccgt aatgccatct tatttcgtaa tggattgaga atgctggatt
    28141 tttaattata ttacgcgcag tattaatcgc gtaaatgttt tgcggtcagc aacggtgggg
    28201 gatccattgt tctgttcaat gaataccatc atacatttga atcaggagtc ggtatgatga
    28261 ttttggtgac ggggggcgca cggagcggga agagtcgcca cgcagaggcg cttattgggg
    28321 actcttcaca ggttctgtat atcgctacct cgcaaatcct tgatgatgag atggctgcac
    28381 ggatagaaca tcatcggcaa ggccgcccgg agcactggcg cacagtggag cgctggcaac
    28441 atcttgatga attaattcat gcagacatta acccgaatga ggttgtgttg cttgaatgcg
    28501 ttaccacaat ggtgactaat ctgttgtttg attatggcgg cgataaagac cctgatgaat
    28561 gggattatca ggcgatggaa caggtgatta atgctgagat tcagtcgttg attgctgcct
    28621 gccaacgttg ccccgcaaag gttgtattag tgactaacga agtgggaatg gggattgtgc
    28681 cggagagtcg tctggcacga cattttcgtg atattgccgg gcgggtaaat cagcagttgg
    28741 ccgctgcggc aaatgaagta tggctggtgg tttcgggtat tggagtaaaa atcaaatgag
    28801 taaattattt tgggcgatgc tctcatttat tacgcgtctg cctgtaccgc gtcgctggtc
    28861 ccagggactg gatttcgagc attattctcg cggtattatt acttttcctt tgattggatt
    28921 attgcttggc gcgattagcg ggctggtctt catggtgctg caggcatggt gtggcgcacc
    28981 actggcggca ctgtttagcg tacttgtgct ggtgctgatg accgggggat tccatctgga
    29041 cggcctcgct gatacctgtg atggcgtatt ttctgcacgt agccgcgatc gcatgttgga
    29101 aatcatgcgt gatagccgtt taggcaccca cggcggtctg gcattgattt ttgtggtact
    29161 ggcaaagatt ctggtgttaa gcgagttggc tctgcgtggc gaaccgatcc ttgcatcgct
    29221 ggcggcagca tgtgcggtca gccgcgggac tgccgcatta ttgatgtatc gtcatcgtta
    29281 tgcccgggaa gaagggcttg gcaatgtgtt cattggcaaa attgatgggc gacaaacctg
    29341 cgtcacactc ggcttagccg ctatttttgc tgccgtatta ttgccgggta tgcatggtgt
    29401 ggctgctatg gtggtgacga tggtggcgat tttcatcctc ggtcagcttc tcaaacgtac
    29461 gctgggcggg caaaccggcg atacgctggg agctgctata gagcttggtg aactggtctt
    29521 cctgctggca ctgctataaa gagacgtgac atgcaaacac ttgccgattt actgaatacg
    29581 atccctgcca tcgatcctgc cgcgatgtcg cgtgcacaac ggcatattga cgggttactc
    29641 aaacctgttg gtagcctggg aaggctggag gcgcttgcca tacaactggc aggaatgccg
    29701 gggttgaatg gcataccgca tgtgggcaaa aaagcggtac tggttatgtg tgccgatcac
    29761 ggcgtctggg aggaaggggt cgctatttcc ccaaaagaag tgacagccat tcaggctgaa
    29821 aatatgaccc gcggaacaac cggcgtgtgt gtgctggcag cacaagcggg cgctaacgtc
    29881 tacgtaattg atgttggtat tgatactgct gagcctatcc ccgggcttat caacatgcgt
    29941 gttgctcgag gtagtggcaa tattgcttca gctccggcaa tgagtcgcca tcaggcagaa
    30001 aagttgcttt tggacgtcat atgttatacg cgggagctgg caaaaaacgg tgttacgctg
    30061 tttggtgtag gtgaactggg gatggcaaac acgacaccgg cagcggcaat agtcagcaca
    30121 atcactggcc gggctcctga agaagtggtt gggattggcg caaacctgcc gacagataaa
    30181 ctggctaata aaattgatgt tgtgcgccgg gcgattacgt tgaatcaacc aaatccgcag
    30241 gatggcgttg atgtcctggc aaaagtgggt ggatttgatt tggtcggaat ggctggcgtg
    30301 atgttaggcg ctgcttcctg cggtttaccc gtgttgctgg atggatttct ttcttatgct
    30361 gccgcgctcg cagcctgcca gatgtctcct gcaatcaaac cgtatctcat tccttctcac
    30421 ctgtcggcag aaaaaggggc gcgtattgcg ctgtcgcatt tggggctgga gccttatctc
    30481 aatatggaga tgcgtttagg tgaggggagt ggcgcagctc tggcgatgcc catcatcgaa
    30541 gctgcctgtg cgatatataa caacatgggc gaacttgctg ccagtaatat tgttctaccg
    30601 gggaatacga cttctgattt gaacagttaa aaacgaaaag tctgataaaa gctatactta
    30661 acggatagct ttcgcgactt aggaaaggga catgatgcgt cgtgtaaata ttttttgctc
    30721 atttgctctg ctttttgcca gccatactag cctggctgta acttatccat tacctccaga
    30781 gggtagccgt ttagtggggc agtcgtttac tgtaactgtt cctgatcaca atacccagcc
    30841 gctggagact tttgccgcac aatacgggca agggttaagt aacatgctgg aagcgaaccc
    30901 gggcgctgat gtttttttgc cgaagtctgg ctcgcaactc accattccgc agcaactgat
    30961 tttgcccgcc actgttcgta aagggattgt ggttaacgtc gctgagatgc gtctttatta
    31021 ctacccacca gacagtaata ctgtggaagt ctttcctatt ggtatcggcc aggctgggcg
    31081 agaaaccccg cgtaactggg tgactaccgt tgaacgtaaa caagaagctc caacctggac
    31141 gccaacgccg aacactcggc gcgaatatgc gaaacgaggg gagagtttgc ccgcatttgt
    31201 tcctgcgggc cccgataatc ccatggggct gtacgcgatt tatattggca ggttgtatgc
    31261 catccatggt accaatgcca attttggtat tgggctccgg gtaagtcagg gctgtattcg
    31321 tctgcgcaat gacgatatca aatatctgtt tgataatgtt cctgttggga cgcgtgtgca
    31381 aattatcgac cagccagtaa aatacaccac tgaaccagat ggctcgaact ggctggaagt
    31441 tcatgagccg ttgtcgcgca atcgtgcaga atatgagtct gaccgaaaag tgccattgcc
    31501 ggtaacccca tctttgcggg cgtttatcag cgggcaagaa gttgatgtaa atcgcgcaaa
    31561 tgctgcgttg caacgtcgat cgggaatgcc tgtgcaaatt agttctggtt caagacagat
    31621 gttttaagag cgttggtaat tagaaagcaa aagcctgcta gaaagcaggc ttttttgaat
    31681 ttggctcctc tgactggact cgaaccagtg acatacggat taacagtccg ccgttctacc
    31741 gactgaacta cagaggaatc gtgtgaacgg ggcgcatatt aatggcagtg catggtgatg
    31801 tcaaagggtg aaatgcattt ttttgtttgt ttgctgtcaa tttcaacaaa gtggtgagct
    31861 ttcaatctta ttgggtaatg aaccatcgtg gtgcataccc tccttttata gggcagggga
    31921 acgcgacagc tgattaaagg agcaaatgac gaatctatca taatctctta tttgacagtt
    31981 ggttagcttg tacatcaacg ccaaaataaa actggcaagc atcttgcaat ctggttgtaa
    32041 gtaatagcgg cacttgggcc gattcttaaa aaccggaggc aacatgaact tcagacgcct
    32101 gaaatacttc gtaaaaattg tagatattgg tagcctgacc caggctgctg aagtattgca
    32161 tatcgcacaa ccagcgctca gccagcaggt tgccacactg gaaggtgagt taaatcaaca
    32221 acttttgatc cgtacaaagc ggggcgttac gccaacagac gccggaaaaa ttctctatac
    32281 ccatgcgcgg gccattttac gtcagtgtga acaggcccaa ctggcggtgc ataacgttgg
    32341 tcaggcatta tcggggcaag tctcgattgg ctttgcacca ggaaccgctg cgtcatccat
    32401 caccatgccc ttattacagg cggttcgcgc tgaatttccg gagatcgtta tctatcttca
    32461 tgaaaatagt ggtgcagtgc ttaacgaaaa attgataaat caccaactcg atatggcggt
    32521 gatttatgag cattcccctg tggctggtgt atccagtcag gctttgctga aagaagatct
    32581 ttttctggta ggaactcaag attgcccggg gcaaagcgtt gatgtgaatg ctattgcgaa
    32641 aatgaacctc tttctcccca gtgattacag tgctattaga cttcgtgttg atgaggcttt
    32701 ttccctacgg cgactcacgg caaaagttat tggtgaaatt gagtctattg ccacgcttac
    32761 cgcagcgatt gccagcggca tgggcgttgc agtattaccc gaatcggccg cgcgttcgtt
    32821 atgtggcgca gtaaatgggt ggatgtcacg cattaccact ccttccatga gtctctcttt
    32881 gtcattaaat ttacccgcca gagcgaactt atcgccacag gcacaggcag tgaaagagtt
    32941 gttaatgtca gtgattagtt ctccagtgat ggaaaaaagg cagtggcaat tggtgagcta
    33001 agtgttatat cgggatggaa taagatgcgg gtttttatta tttgttatgc cgggcattag
    33061 actttaacaa taacgggaaa tctgaactgc ccggagttta ccgtgaattt ccaacaacta
    33121 aagataatcc gcgaggctgc acgtcaggat tacaacctga cagaggttgc gaatatgctt
    33181 tttacctcac agtcaggcgt cagccgtcat attcgggaac tggaggatga acttggcatc
    33241 gaaatatttg ttcgacgagg taagcgactg ctgggcatga ctgaaccggg caaagcatta
    33301 ctggtcattg cagaacgtat tctgaatgaa gccagtaatg ttcgtcggct tgcagacctg
    33361 tttaccaacg atacgtctgg cgttctcact attgcaacga cgcatactca ggcacgttat
    33421 agcttgccag aggtcattaa agcttttcgc gaacttttcc cggaggttcg gctcgagcta
    33481 atccagggga cgccacagga aattgcgaca ttgttgcaaa atggcgaagc tgatattggt
    33541 atcgccagcg agcgtttgag taatgacccg cagctcgtcg ccttcccgtg gtttcgttgg
    33601 caccatagtt tgcttgttcc acacgatcat cccttgacgc aaatttcacc attgacgctg
    33661 gaatcaatag cgaagtggcc gttaatcact taccgacagg ggattacggg gcgctcacgt
    33721 attgatgacg catttgcccg caaaggtttg ctggcagata ttgtattaag tgcgcaggat
    33781 tctgatgtca ttaaaaccta tgttgctctt gggcttggga tcggattagt tgccgaacaa
    33841 tccagcggcg aacaagagga agagaattta atccgtctgg atacgcggca tcttttcgat
    33901 gctaatactg tctggttggg actgaagcga ggacaacttc agcgtaacta tgtctggcgc
    33961 tttctggaac tttgtaatgc aggactgtca gttgaggata tcaagcggca ggtgatggaa
    34021 aacagtgaag aggaaattga ttatcagata tagcaaaaag cccgctataa aagcgggctt
    34081 ttcagaaatt tggctcctct gactggactc gaaccagtga catacggatt aacagtccgc
    34141 cgttctaccg actgaactac agaggaatcg ctgttgaggc acatcttaac ggcgaaaaat
    34201 cttttgtcaa acccgatttt ttaattcccc aattgtttgc cgtttctatc aacagtttgt
    34261 tgcatttgca gacaatttgt tggcgaaaat ctttgcagct ttgctgattc tccctcatta
    34321 tttgaaatgt ggtttcactt tctgcaatta aggtcggctt tgaatatctc ctctgcttta
    34381 cgccaggttg ttcacggcac tcgctggcac gctaaacgca agagctacaa agtgttgttc
    34441 tggcgcgaga taaccccgct tgctgttcct atcttcatgg agaatgcctg tgtcctgttg
    34501 atgggtgtcc tgagcacttt tctggtcagc tggctgggaa aagatgcgat ggccggcgtg
    34561 ggattggcgg acagcttcaa tatggtcatt atggcttttt ttgcagctat cgatcttggt
    34621 actactgtcg ttgtggcatt tagtctcggt aagcgggatc gacgacgagc gagggtggcg
    34681 acgcggcagt cattggtgat catgacgttg tttgccgtac tgttggcaac gcttattcat
    34741 cattttggcg aacaaattat tgatttcgtc gcgggtgatg ccacgacaga agttaaagca
    34801 ctggcgttga cttatctgga gctgacggta ctcagttatc cagcagctgc catcactttg
    34861 attggtagcg gggcacttcg tggtgcaggg aatacgaaaa taccgctact gattaacggt
    34921 agcctgaata ttcttaatat tattattagc ggcatattga tttacggcct tttctcctgg
    34981 ccgggactgg gatttgtcgg ggctgggttg ggtttaacca tttctcgtta tattggcgca
    35041 gttgcaattt tgtgggtgct ggcgattggt tttaatcctg cgctaaggat ttcgttaaag
    35101 agctatttta aaccgctgaa ttttagcatt atctgggaag tcatggggat tggtattcca
    35161 gcgagtgtcg aatcagtgtt atttaccagt ggtcggttat taacccaaat gttcgttgcc
    35221 gggatgggga ccagtgttat tgccggaaat tttatcgcgt tttcaattgc ggctcttatc
    35281 aacttacccg gaagtgcgct cggctctgct tctacgatca ttacaggccg aaggttgggg
    35341 gtagggcaga tagcgcaagc agagattcag ttgcggcatg tgttctggct gtccactctt
    35401 ggattaacgg ccatcgcctg gctaacggct ccctttgccg ggcttatggc atcgttttac
    35461 acccaggatc cacaggttaa acatgtcgtt gtgattctga tttggctaaa tgctttattt
    35521 atgcctattt ggtccgcctc atgggtgcta cccgctggat ttaaaggtgc tcgtgatgcc
    35581 cgttacgcca tgtgggtttc gatgttgagc atgtggggtt gccgggttgt cgtcggttat
    35641 gtgctgggca tcatgcttgg ctggggtgtg gttggtgtct ggatgggaat gtttgccgac
    35701 tgggctgtgc gggccgtgct gttttactgg cgaatggtta ctggacgttg gctatggaaa
    35761 taccctcgat ccgagccgca aaagtgtgaa aaaaagccag ctgtgtcgga ataaacgaca
    35821 aaatgcagat tatttcagca aacgatttca aatttaaaaa acaggctttg acattatggg
    35881 tgggcatcgc taatattcgc ctcgttctca cgattcctct gtagttcagt cggtagaacg
    35941 gcggactgtt aatccgtatg tcactggttc gagtccagtc agaggagcca aattttagtt
    36001 ttgagacatc tctatgagtc tcaaaacagt taaaaaataa aaattatttt tacccggtta
    36061 ccttgtaaaa aagtgaccgg gttttttgat ttctgtgttt cgtgcgctta atcgagtctc
    36121 acgcttcagt gagcaagttg cccccaacag acatcacgat tcgcaaggtc aaaaactctg
    36181 ttccatgaag taccgtacaa agataaagag aaaaatgcct tatgcgggat gtcgctatcg
    36241 cgtctttatc gggaaactat gcgttattgc cactttgcct tctgtaatca gaaaaagaag
    36301 aactggaatt ttaataaata ttatttctct gggaacgggg attt
//
LOCUS       DAZUDJ010000051        35866 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.051, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000051 DAZUDJ010000000
VERSION     DAZUDJ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35866
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.051"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(153..1328)
                     /gene="ubiF"
                     /locus_tag="ACHY1N_003265"
     CDS             complement(153..1328)
                     /gene="ubiF"
                     /locus_tag="ACHY1N_003265"
                     /EC_number="1.14.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706550.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016709 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, NAD(P)H as one donor, and incorporation
                     of one atom of oxygen [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-demethoxyubiquinol 3-hydroxylase"
                     /protein_id="HFS4045516.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQHGFSVTVIEHAEPAPFVA
                     DSQPDVRISAISAASVSLLKGLGVWDAVQAMRCHPYRRLETWEWETAHVMFDAAELKL
                     PLLGYMVENTVLQQALWQALEAHPKVTLRVPGSLIALHRDNDLQELELKGGEVIRAKL
                     VIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPL
                     FDNWASLVWYDSPVRIRQLQNMNMAQLQAEIAKHFPSRLGYVTPLAAGAFPLTRRHAL
                     QYVQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLVNARSYGEAWASYPVLKRY
                     QMRRMADNFIMQSGMDLFYAGFSNNLPPLRFVRNLGLMAAERAGVLKRQALKYALGL"
     gene            1474..2898
                     /gene="miaB"
                     /locus_tag="ACHY1N_003266"
     CDS             1474..2898
                     /gene="miaB"
                     /locus_tag="ACHY1N_003266"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HFS4045517.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSY
                     SFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENDLGVGYYQP"
     gene            3051..4091
                     /gene="ybeZ"
                     /locus_tag="ACHY1N_003267"
     CDS             3051..4091
                     /gene="ybeZ"
                     /locus_tag="ACHY1N_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415193.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFS4045518.1"
                     /translation="MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRD
                     NHFKLTGRPICVTAAADILRSLYVDTAPMRGQIQDIEPEQIHLAIKEARVLEQSAESV
                     PEYGKAVNIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
                     ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIER
                     NVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDL
                     PRNTKSGLRHAIEVLADVEEISFNFFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAAL
                     AAERKREEQEQK"
     gene            4088..4555
                     /gene="ybeY"
                     /locus_tag="ACHY1N_003268"
     CDS             4088..4555
                     /gene="ybeY"
                     /locus_tag="ACHY1N_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014169133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFS4045519.1"
                     /translation="MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIR
                     VVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGK
                     PLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE"
     gene            4645..5523
                     /gene="corC"
                     /locus_tag="ACHY1N_003269"
     CDS             4645..5523
                     /gene="corC"
                     /locus_tag="ACHY1N_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308723.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HFS4045520.1"
                     /translation="MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA
                     SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVKIPDDSPQPKLDE"
     gene            5548..7086
                     /gene="lnt"
                     /locus_tag="ACHY1N_003270"
     CDS             5548..7086
                     /gene="lnt"
                     /locus_tag="ACHY1N_003270"
                     /EC_number="2.3.1.269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0042158 - lipoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HFS4045521.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGL
                     QALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLS
                     LYTGLFAGVLSRLWPKTTWLRVAIAAPSLWQVTEFLRGWVLTGFPWLQFGYSQIDGPL
                     KGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIQWFTPQP
                     EKTIQVSMVQGDIPQSLKWDGDQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEIN
                     QQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLGKGAPYSYKSADRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSANGIELTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYARTGNWPLWVLTALFGFAAVLMSLR
                     ARKR"
     gene            complement(7164..9041)
                     /locus_tag="ACHY1N_003271"
     CDS             complement(7164..9041)
                     /locus_tag="ACHY1N_003271"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFS4045522.1"
                     /translation="MSASSVKPLNVQLPAITLILFALCIGIFCYLAQWMSYEEVDQSA
                     LIHLGANVAPLTLSGEPWRLLSSIFLHSSVSHLLMNMFAFLVVGGVAEQILGKWRLLI
                     TWLFSGVFGGLISACYALRESEQIVISVGASGAILGIAGAAIATQFASGTGTYHKNQR
                     RVFPLLGMVALTLLYGARQTGIDNACHIGGLIAGGALGWLSARLSGQNRLVTEGGIIV
                     AGSLLLTGAIWLAQQQMDESVLQVRQSLREAFYPQEIEQERRQKKQQLAEERNALRET
                     LSAPVSREQASGDLLAEIADIHDMAISRDGNTLYAAIEDTNSIVVFDLGQKKILHTFT
                     APIAKEKSVKHCGGCKDQGVRSLALSPDEKLIYATSFEANALSVINVATGEIIQSITT
                     GAHPDSLILSRDGTKAWVMNRTSNSVSAIDLVAYQHVADIPLEKYDGTGTSGKPGAWV
                     MALSPDERTLLVPGEGRGNIVRINTITHQKEDFPAGDARGTISAMRFRPENGEVIFAD
                     SQGISRISIGDQQTSIMTQWCSRSVYSVEGISPDGQYLALVSYGLQGYVILLNINAGQ
                     IIGVYPASYVNHLRFSADGRKIFVMAKNGLIQMDRTRSLDPQAIIRHPQYGNVACIPE
                     P"
     gene            9496..10404
                     /gene="gltI"
                     /locus_tag="ACHY1N_003272"
     CDS             9496..10404
                     /gene="gltI"
                     /locus_tag="ACHY1N_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter
                     substrate-binding protein GltI"
                     /protein_id="HFS4045523.1"
                     /translation="MQLRKPATAILALALSAGLAQADDAAPVAGSTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFADLKDKAVVVTS
                     GTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKEPNDKALN"
     gene            10574..11314
                     /gene="gltJ"
                     /locus_tag="ACHY1N_003273"
     CDS             10574..11314
                     /gene="gltJ"
                     /locus_tag="ACHY1N_003273"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HFS4045524.1"
                     /translation="MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTIALSICAWIIAF
                     LVGSFFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVIPELLPEKIGMWFKA
                     ELDPNIQFFLSSMLCLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAVIMLVMTLVERKVRLPGNMGGK"
     gene            11314..11988
                     /gene="gltK"
                     /locus_tag="ACHY1N_003274"
     CDS             11314..11988
                     /gene="gltK"
                     /locus_tag="ACHY1N_003274"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HFS4045525.1"
                     /translation="MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVM
                     RLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSY
                     LKRRTA"
     gene            11988..12713
                     /gene="gltL"
                     /locus_tag="ACHY1N_003275"
     CDS             11988..12713
                     /gene="gltL"
                     /locus_tag="ACHY1N_003275"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP-binding
                     protein GltL"
                     /protein_id="HFS4045526.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRDKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDS
                     PKDAFFDDPKSDRAKDFLAKILH"
     gene            12831..13766
                     /gene="rihA"
                     /locus_tag="ACHY1N_003276"
     CDS             12831..13766
                     /gene="rihA"
                     /locus_tag="ACHY1N_003276"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050263 - ribosylpyrimidine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0006206 - pyrimidine nucleobase metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HFS4045527.1"
                     /translation="MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEK
                     TLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPAFAPQNC
                     TAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAE
                     LLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYSQGMTVV
                     DYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA"
     gene            13850..15520
                     /gene="hscC"
                     /locus_tag="ACHY1N_003277"
     CDS             13850..15520
                     /gene="hscC"
                     /locus_tag="ACHY1N_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000367910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HscC"
                     /protein_id="HFS4045528.1"
                     /translation="MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIIS
                     MDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSL
                     KEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGL
                     HTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVHASAGDNFLGGEDFTHMLVDDVLKRA
                     DVARTTLNESELAALYACVEAAKCSNQSPLHIRWQYQDETRECEFYENELEDLWLPLL
                     NRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIV
                     ALGAAIQAACRLRSEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRV
                     ETYSTMHPEQDSITVNVYQGENHKVKNNILVESFDVPLKKTGAYQSIDIRFSYDINGL
                     LEVDVLLEDGSVKSRVINHSPVTLSAQQIEESRTRLSALKIYPRDMLINRTFKAKLEE
                     LWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRRASVYLAIETS"
     gene            complement(15580..17031)
                     /gene="djlC"
                     /locus_tag="ACHY1N_003278"
     CDS             complement(15580..17031)
                     /gene="djlC"
                     /locus_tag="ACHY1N_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlC"
                     /protein_id="HFS4045529.1"
                     /translation="MKTCWQILEIESTTQIDIIRQAYLARLPLCHPETDPQGFKALRQ
                     AYEEALRLAVNPVEEADDEEKDAAAEHEILRAFRTLLDSESDRFQPSAWQKFIQQLNT
                     WNMEDVDQLRWPLCAIAIEARYLSLNCASLLAERLNWHSFNDSEGMDEEEREAFLEAI
                     QAGDCFDFLSLLEYPVALQNQTVEYYFALERCCRYHPDYVTAFLAMEGPWFIPDDAKL
                     HRKLLRWYSSVQTGMAELIPVAKQWQMEEPESEDARYYLCAQRLYCGEGESLLADLCA
                     YRESYPSTQADNLLLQWSKSHCPDYFALLVMVIEARSMVDAQGQPLKYVPGESARTRL
                     LWAEILHSGKLSPLGQSFIESLFFKRKAWAWWKSRVGSETEEDSPLLDLYRVAEQVVL
                     EAFPKQEMLARLNTRLEGGDAHPLEAIITRMLLTKVKLEPEDEDVDEPTPENHEEKND
                     EGEKPQSITSIIKISLTVLVIGYALGKIAMLFS"
     gene            complement(17028..17735)
                     /gene="ybeU"
                     /locus_tag="ACHY1N_003279"
     CDS             complement(17028..17735)
                     /gene="ybeU"
                     /locus_tag="ACHY1N_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HFS4045530.1"
                     /translation="MNKEEQYLLFALSAPMEILNQGCKPAHDSPKMYTGIKEFDLSSS
                     WGINNRDDLIQTIYQMTDDGHANDLAGLYLTWHRSSPEEWKALIAGGSERGLIYTQFV
                     AQTAMCCGEGGIKAWDYVRMGFLSRVGVLNNWLTEEDSLWLQSRVYVRAHHYYHSWMH
                     YFSAYSLGRLYWQSSQCEDNTSLREALTLYKYDSAGSRMFEELAAGSDRFYATLPWQP
                     LTVQPECPVTLKDVSDL"
     gene            17836..18390
                     /gene="ybeT"
                     /locus_tag="ACHY1N_003280"
     CDS             17836..18390
                     /gene="ybeT"
                     /locus_tag="ACHY1N_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFS4045531.1"
                     /translation="MNKKLMYIFAIFIVAAITCISQPKKTTLRDKAMVNYAFDYLSSP
                     GSLPLTTAATELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRA
                     QSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGTGINVNHYESQ
                     KWLKLAAKQHYKNAERLLAGLPAH"
     gene            complement(18400..19827)
                     /gene="djlB"
                     /locus_tag="ACHY1N_003281"
     CDS             complement(18400..19827)
                     /gene="djlB"
                     /locus_tag="ACHY1N_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="HFS4045532.1"
                     /translation="MKNCWKILEIEETTDVDIIRRAYLALLPSFHPETDPQGFKQLRQ
                     AYEEALRIAQSPAKSVWQPEEYEVAEHEILLAFRALLASDSERFLPSAWQRFIQQLNY
                     CSMEEIDELRWSLCTIAMNTAHLSFECVVLLAERLRWLQEENVGEIDEEELESFLYAI
                     AKGNVFNFQTILHLPVAVQNDTIDFYQMFARIWSSHPEWLTLYLAQHRAVIIPDDAKL
                     HRNLLRWYSAGRLGIPELLDYARSWREAESDNEDARYYEYAQRVYCGEGESLLAELCD
                     YWREYPSTQADALILQWCRQHRVDYYPLVVMMIEARELVNDQGKPLLYIPGDSARTRF
                     HLYEILSDEKLSALGRSLVEMVLHKGRKPRISLTRDTEHPLWPLYLVAKQLVQANQPT
                     EESLMPIVSRLDAEDRCPLEALIIRRLLIQAANFTEKQTVEPEPQPQPMPVDDGGPGC
                     LGIIKIIFYIFIFAGLIGKILHLFG"
     gene            complement(19824..20531)
                     /gene="ybeR"
                     /locus_tag="ACHY1N_003282"
     CDS             complement(19824..20531)
                     /gene="ybeR"
                     /locus_tag="ACHY1N_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HFS4045533.1"
                     /translation="MDMESQKILFALSTPMEIRNECCLPSHSSPKMYLGTCFFDLSSS
                     WGIDARDDLLRTIHRMIDNGHAARLAGFYHRWFRYSPCEWRDYLAELNEQGQAYAQFV
                     ASTAECCGEGGIKAWDYVRMGFLSRMGVLNNWLSEEESLWIQSRIHLRALRYYRNWRQ
                     YFAGYTFGRQYWQSPEDDHLQLLREFLARKEYDDSGNDMFYQLFASDDAYYPTLSWQP
                     LAYYSACPETLKDMSDL"
     gene            20695..21672
                     /gene="ybeQ"
                     /locus_tag="ACHY1N_003283"
     CDS             20695..21672
                     /gene="ybeQ"
                     /locus_tag="ACHY1N_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415177.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sel1 family TPR-like repeat protein YbeQ"
                     /protein_id="HFS4045534.1"
                     /translation="MIFTSSCCDNLSIDEIIERAEKGDCEAQYIVGFYYNRDSAIDSP
                     DDEKAFYWLKLAAEQGHCEAQYSLGQKYTEDKSRHKDNEQAIFWLKKAALQGHTFASN
                     ALGWTLDRGEAPNYKEAVVWYQIAAESGMSYAQNNLGWMYRNGNGVAKDYALAFFWYK
                     QAALQGHSDAQNNLADLYEDGKGVAQNKTLAAFWYLKSAQQGNRHAQFQIAWDYNAGE
                     GVDQDYKQAMYWYLKAAAQESVGAYVNIGYMYKHGQGVEKDYQAAFEWFTKAAECNDA
                     TAWYNLAIMYHYGEGRPVDLRQALDLYRKVQSSGTRDVSQEIRETEDLL"
     gene            complement(21742..22224)
                     /gene="ybeL"
                     /locus_tag="ACHY1N_003284"
     CDS             complement(21742..22224)
                     /gene="ybeL"
                     /locus_tag="ACHY1N_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HFS4045535.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFIRVIKESLWQELADITDKTQLEWR
                     EVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
                     "
     gene            22459..25041
                     /gene="leuS"
                     /locus_tag="ACHY1N_003285"
     CDS             22459..25041
                     /gene="leuS"
                     /locus_tag="ACHY1N_003285"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFS4045536.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNP
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDH
                     EAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEY
                     KEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTA
                     KGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     TDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVED
                     STLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            25056..25637
                     /gene="lptE"
                     /locus_tag="ACHY1N_003286"
     CDS             25056..25637
                     /gene="lptE"
                     /locus_tag="ACHY1N_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0043165 - Gram-negative-bacterium-type cell
                     outer membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HFS4045537.1"
                     /translation="MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPN
                     GPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIM
                     TVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLP
                     SIRAADIRSDEEQTSTTTDTPATPARVSTTLGN"
     gene            25637..26668
                     /gene="holA"
                     /locus_tag="ACHY1N_003287"
     CDS             25637..26668
                     /gene="holA"
                     /locus_tag="ACHY1N_003287"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFS4045538.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAA
                     QGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTG
                     LLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNL
                     ELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRGMMGEALNRLSQTQLRQAVQLLTRTELTLKQDYGQSVWAELEGLSLLLCHK
                     PLADVFIDG"
     gene            26670..27311
                     /gene="nadD"
                     /locus_tag="ACHY1N_003288"
     CDS             26670..27311
                     /gene="nadD"
                     /locus_tag="ACHY1N_003288"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFS4045539.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPP
                     HRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPL
                     AFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPED
                     LHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR"
     gene            27335..27946
                     /gene="cobC"
                     /locus_tag="ACHY1N_003289"
     CDS             27335..27946
                     /gene="cobC"
                     /locus_tag="ACHY1N_003289"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043755 - alpha-ribazole phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HFS4045540.1"
                     /translation="MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLHG
                     VSFDLVLCSELERAQHTARLVLSDRQLPVHIIPELNEMFFGDWEMRHHRDLMQEDAEN
                     YSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEFQHYQNILVVSHQGVLSLLIARL
                     IGMPAEAMWHFRVDQGCWSTIDINQKFATLRVLNSRAIGVENA"
     gene            28206..28523
                     /gene="rsfS"
                     /locus_tag="ACHY1N_003290"
     CDS             28206..28523
                     /gene="rsfS"
                     /locus_tag="ACHY1N_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFS4045541.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQESRAAGLLPLGVEGENSADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            28527..28994
                     /gene="rlmH"
                     /locus_tag="ACHY1N_003291"
     CDS             28527..28994
                     /gene="rlmH"
                     /locus_tag="ACHY1N_003291"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFS4045542.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSTLTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            29025..30926
                     /gene="mrdA"
                     /locus_tag="ACHY1N_003292"
     CDS             29025..30926
                     /gene="mrdA"
                     /locus_tag="ACHY1N_003292"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HFS4045543.1"
                     /translation="MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     VRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVV
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVT
                     DPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIH
                     SGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAEN
                     PAVAAAEDH"
     gene            30929..32041
                     /gene="mrdB"
                     /locus_tag="ACHY1N_003293"
                     /gene_synonym="rodA"
     CDS             30929..32041
                     /gene="mrdB"
                     /locus_tag="ACHY1N_003293"
                     /gene_synonym="rodA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HFS4045544.1"
                     /translation="MTDNPNKKTFWDKVHLDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVIMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTGIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPE
                     SDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            32052..33140
                     /gene="rlpA"
                     /locus_tag="ACHY1N_003294"
     CDS             32052..33140
                     /gene="rlpA"
                     /locus_tag="ACHY1N_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HFS4045545.1"
                     /translation="MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEIS
                     GADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFD
                     PTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSN
                     NTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVSGPQGDILP
                     VSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPA
                     MVTPQAASQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGP
                     FASKAEASTLQQRLQTEAQLQSFITTAQ"
     gene            33280..34491
                     /gene="dacA"
                     /locus_tag="ACHY1N_003295"
     CDS             33280..34491
                     /gene="dacA"
                     /locus_tag="ACHY1N_003295"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HFS4045546.1"
                     /translation="MNTIFSARIMKRLALTTALCTAFISAAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG
                     REAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            34602..34865
                     /gene="ybeD"
                     /locus_tag="ACHY1N_003296"
     CDS             34602..34865
                     /gene="ybeD"
                     /locus_tag="ACHY1N_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF493 family protein YbeD"
                     /protein_id="HFS4045547.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYT
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL"
     gene            34966..35607
                     /gene="lipB"
                     /locus_tag="ACHY1N_003297"
     CDS             34966..35607
                     /gene="lipB"
                     /locus_tag="ACHY1N_003297"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415163.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033819 - lipoyl(octanoyl) transferase
                     activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HFS4045548.1"
                     /translation="MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELV
                     TLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKISQWKPEATTNNIVPRLLENILALLNNPDFEYITA"
BASE COUNT         8952 a         9137 c         9062 g         8715 t
ORIGIN      
        1 attaaaaaag ctcgcttcgg cgagcttttt gcttttctgc gttcattcaa tgtcgaatgc
       61 gatgttgaca cgtcttatcc ttcaatgtcg gatgcgacgc tgccgcgtct tatccgacct
      121 acggttggca cgcatccggc aatgttgtaa ggctacaacc ctaacgcata tttcagcgcc
      181 tgacgtttca acacgccagc acgctctgcc gccattaacc cgagattacg cacaaaacgc
      241 agcggcggca gattattact gaatccggca taaaacagat ccataccact ttgcataatg
      301 aagttatccg ccatgcgccg catctggtaa cgcttgagga caggataact ggcccacgct
      361 tcaccgtagc tgcgggcatt caccagaaca tcaatcaggg catcgacatc acgataacca
      421 agattcaccc cctgccccgc cagcggatgg atggtatgcg cggcatcgcc caccagcgca
      481 agccccggct gcacatactg caacgcatgt cggcgcgtca gcggaaacgc accagcggca
      541 agcggtgtaa cgtaacccag acgcgacggg aaatgcttcg cgatttccgc ctggagttgc
      601 gccatattca tattctgcaa ctggcgaata cgtaccggag agtcatacca caccagcgat
      661 gcccagttat caaacaacgg cagaaacgca cgcggtccgt ccggggtaaa ttgctgccag
      721 gtgctgtcgc cgggatcgtt ctcacactgt acgctaatca acatacacga ctgcgcatac
      781 tgccaggcat gaacgccaat tcccgccatc tgccgcacct gcgaatttgc gccgtcagca
      841 ccaatcacca gcttcgcgcg aatcacttca ccgcccttca gttccagctc ctgaagatca
      901 ttatctcgat gtaatgcaat cagcgagcct ggcacacgta acgttacttt cggatgcgct
      961 tccagcgcct gccacaatgc ctgttgcagg acggtgtttt ccaccatata gccaagcagc
     1021 ggcagcttaa gttcagcggc gtcaaacatc acatgcgccg tttcccactc ccacgtttcc
     1081 agtctgcggt aaggatggca acgcatagcc tgtactgcat cccagacccc taacccttta
     1141 agcaatgata ccgatgcggc gctgatcgcc gagatccgca cgtccggttg gctatcagcg
     1201 acaaacggtg caggttctgc gtgctcgatc accgttaccg aaaatccgtg ctgtgccagc
     1261 cccagcgcca gtgcgccgcc gaccattcct ccgccgacaa tggcaatttc cgttggttga
     1321 tttgtcatgg tcaatcatcc tgttagcaat atgctttaag tttacaggat ttttaccccc
     1381 aagggctgat aacgctcata ctggtcacaa cggcagcaaa gcattacact atgcgccctg
     1441 cattcctggc tactatttcg caagagcaag tcgatgacca aaaaactcca tattaaaacc
     1501 tggggctgtc agatgaacga gtacgattca tcgaagatgg ccgatctgct ggatgccacc
     1561 cacggctatc aactgaccga cgtggcggaa gaagcggatg tgctgctgct gaacacctgc
     1621 tcaatccgcg agaaggctca ggaaaaagtc ttccatcagt tgggtcgctg gaaactgtta
     1681 aaagagaaga atccagacct gattatcggc gtcggtggct gcgtggcatc gcaagaaggc
     1741 gagcacattc gccagcgcgc ccactatgtc gatattattt ttgggccgca aacactgcac
     1801 cgtctgccgg agatgatcaa ctccgtgcgc ggcgaccgca gcccggttgt agatatcagc
     1861 ttcccggaaa tcgagaagtt tgaccgtctg ccggaaccgc gcgccgaagg gccgaccgcg
     1921 tttgtctcca tcatggaagg ctgcaataaa tattgcacct actgcgtggt gccttacacc
     1981 cgtggtgaag aggtaagccg tccgtccgac gatattctgt ttgagatcgc ccagcttgcg
     2041 gctcagggcg tgcgtgaagt caacctgctc ggtcagaatg tgaatgcctg gcgtggtgag
     2101 aactacgacg gcaccaccgg atcgtttgcc gatctgttgc gtctggttgc tgcgatcgac
     2161 gggatcgatc gtattcgctt taccaccagc catccgatcg aattcaccga cgatatcatc
     2221 gaagtgtatc gcgacacgcc ggagctggtg agcttcctgc atctgccggt acagagcggt
     2281 tccgatcgca ttctgaacct gatgggccgt actcatacgg cactggagta caaagcgatc
     2341 atccgtaaac tgcgtgcggc gcgtccggat attcagatca gttctgactt cattgttggc
     2401 ttccctggcg aaaccaccga agacttcgag aaaacgatga agctgattgc cgacgtcaat
     2461 ttcgacatga gctacagctt tatcttctct gcacgtccag gaacgcctgc cgctgatatg
     2521 gttgatgatg ttccggaaga agagaagaag cagcgtctgt atattctgca agaacgtatc
     2581 aatcagcaag cgatggcatg gagccgtcgg atgctcggca ccacccagcg tattctggta
     2641 gaaggtacat cgcgtaagag catcatggag ctttccgggc gtaccgaaaa taaccgtgtg
     2701 gtcaacttcg agggcacacc ggatatgatc ggtaaattcg tcgatgtaga aattaccgac
     2761 gtctacccga actctctgcg cggtaaagtg gtgcgtactg aagatgaaat gggtctgcgc
     2821 gtggcagaaa cacccgaatc ggtgattgcc cgtactcgca aagaaaatga ccttggcgtg
     2881 ggttattatc agccgtaatt ctcaggcccg ccgttccggt gggccttgtt ttttctctct
     2941 ttatccccat ctttatcgca atgcttgcgc ctttttcctg tggcgtgaat aatttcctta
     3001 taggccggtg aatgttcagc ttccggcggc atacagataa gaggaacggt ttgaacatag
     3061 acactcgcga aatcaccctg gagccagcag acaatgcgcg tctgttgagc ctgtgcggcc
     3121 cgtttgatga caacatcaag cagctcgaac gccgtctcgg catcgagatc aatcgccgcg
     3181 acaaccactt taaactgacc ggccgtccga tttgcgtcac cgctgcggca gacattctgc
     3241 gtagcctgta tgtcgataca gccccgatgc gcggtcagat tcaggatatc gaaccggaac
     3301 agatccacct tgcgattaaa gaagcgcgag tactggagca aagtgcggag agcgtgccgg
     3361 agtacggcaa agcggtcaat atcaaaacca aacgcggcgt aattaagccg cgcacgccaa
     3421 accaggcgca gtacatcgcc aatattctcg accatgacat taccttcggc gttggcccgg
     3481 cgggtacggg taaaacctac ctggcagtgg ctgcggcagt tgatgccctg gagcgtcagg
     3541 agattcgccg tattctgctg actcgtccgg cggtcgaagc cggtgagaaa ctgggcttcc
     3601 tgcctggcga tttaagccag aaagtagacc cgtatctgcg cccgctgtac gacgcgctgt
     3661 ttgaaatgct gggctttgag aaagttgaga aactgattga gcgcaacgtt attgaagtcg
     3721 cgccgctggc ctatatgcgt ggtcgtacgc tgaacgacgc gtttatcatt ctcgatgaga
     3781 gccagaacac caccatcgaa cagatgaaga tgttcctgac ccgtatcggt tttaactcaa
     3841 aagcggttat caccggcgac gtcacacaga tcgacctgcc gcgtaatact aaatcaggct
     3901 tacgtcacgc catcgaagtg ctggccgatg tcgaagagat cagctttaac ttcttccaca
     3961 gcgaagacgt ggttcgtcac ccggtggtgg cgcgtatcgt taacgcctat gaagcctggg
     4021 aagaagccga acaaaaacga aaagcggcgc tggcggcaga acgcaagcgc gaagaacagg
     4081 aacaaaaatg agtcaggtga tcctcgattt acaactggca tgtgaagata attctgggtt
     4141 accggaagag agccagtttc aaacatggct gaatgcggtg atcccgcagt ttcaggaaga
     4201 atcggaagtg actattcgcg tggtcgatac cgccgaaagc cacagtctga atctgaccta
     4261 tcgcggtaag gataagccga ccaacgtgct ctccttcccg tttgaagtgc cgcctggcat
     4321 ggaaatgtcg ctactgggcg atctggttat ctgccgtcag gtggttgaga aggaagctca
     4381 ggagcaaggc aaaccactgg aggcgcactg ggcgcatatg gtggtgcacg gcagtctgca
     4441 tttgttaggt tacgatcaca tcgaagatga cgaagcagaa gaaatggaag ccctcgaaac
     4501 agagattatg cttgctctgg gctatgagga tccgtacatt gccgagaaag aataatttgc
     4561 caggcatttg actggcagac gtccccgccg ttggtgatta acgacggcgt tttgattaac
     4621 taacatgaga acccatacga cgccatgagc gacgacaatt cacacagtag tgacacgata
     4681 agcaacaaga agggattttt ctccctgtta ctcagccaac ttttccacgg tgaaccgaaa
     4741 aaccgtgacg aactgctggc gctgatccgt gattccgggc agaacgacct tatcgacgaa
     4801 gatacgcgcg atatgctcga aggggtgatg gacatcgcag accaacgcgt tcgcgacatc
     4861 atgatccccc gctcccagat gattaccctg aaacgcaacc agacgctgga cgaatgcctt
     4921 gatgtcatca tcgagtccgc ccactcacgt ttcccggtga ttagcgaaga caaagatcac
     4981 attgaaggga ttctgatggc gaaagacttg ctgccgttta tgcgcagcga tgctgaagcc
     5041 ttcagcatgg acaaagtgtt acgtcaggcg gttgtcgttc ctgaaagtaa gcgcgtagac
     5101 cggatgctga aagagtttcg ctctcagcgt taccacatgg cgatcgttat tgacgaattc
     5161 ggtggggttt ccggtctggt gaccattgaa gacatcctgg aactaattgt tggtgagatt
     5221 gaagacgagt atgacgaaga agatgatatc gacttccgtc agctgagtcg tcatacctgg
     5281 accgtgcgcg cactggcttc cattgaagac ttcaacgaag cgttcggcac ccactttagc
     5341 gatgaagagg ttgacactat cggtggtctg gtgatgcagg catttgggca tcttccggcg
     5401 cgtggcgaaa ctatcgacat cgacggttac cagttcaaag tggcgatggc cgacagtcgg
     5461 cgtattattc aggttcatgt caaaatcccg gatgactcac cccagccgaa gctggatgaa
     5521 taaaaccgaa actggataga taactacatg gcttttgcct cattaattga acgccagcgc
     5581 attcgcctgc tgctggcgtt attattcggt gcctgcggaa cgctggcctt ctctccttac
     5641 gatgtctggc ctgcggcgat tatttcgctg atggggcttc aggcgttgac ctttaaccgc
     5701 cgtccactcc agtctgccgc tattggcttt tgctggggat ttggcctctt tggcagcggt
     5761 attaactggg tctatgtcag catcgcgacc tttggcggga tgcctggccc ggttaacatc
     5821 ttcctggtgg tgctgctggc ggcgtatttg tcgctgtata ccggactgtt tgctggcgtg
     5881 ctgtcgcgtc tgtggccgaa aaccacctgg ctgcgcgtgg cgattgccgc cccttctctc
     5941 tggcaagtga ccgagtttct gcgcggttgg gtactgacag gcttcccgtg gttacagttc
     6001 ggctatagcc agattgatgg cccgttaaaa gggctggcac cgataatggg cgtggaagcc
     6061 attaacttcc tgctgatgat ggttagtggc ctgctggcac tggcgttggt caaacgcaac
     6121 tggcgtccgc tggtggtggc cgtcgtgctg tttgccctac ccttcccgct gcgttacatc
     6181 caatggttta ccccacaacc ggagaaaacc attcaggttt cgatggttca gggcgatatt
     6241 ccgcaatcac tgaaatggga tggagatcag cttcttaata cgctgaagat ttactacaac
     6301 gcaacggctc cgctgatggg caaatcatcg ttgattatct ggccggagtc ggcgataacc
     6361 gatctggaaa ttaatcagca accgttcctc aaagcactgg acggtgagtt gcgcgataaa
     6421 ggtagctcgc tggtaaccgg gattgtcgac gcgcgtctca ataagcagaa ccgctacgat
     6481 acctacaaca ccatcatcac gctgggtaaa ggtgcaccgt atagctacaa atcagccgat
     6541 cgctataaca aaaaccatct ggtgccgttt ggcgagtttg tcccgctgga gtcgattctg
     6601 cgtccgttag caccgttctt tgatctgccg atgtcgtcgt tcagccgtgg gccatatatc
     6661 cagccgccgc tgtcggcaaa tggtattgag cttactgcgg ctatttgcta cgagatcatt
     6721 ctcggcgagc aagtgcgcga taacttccgc ccggataccg actatctgct gactatctcc
     6781 aacgatgcgt ggtttggtaa gtctattggt ccatggcagc acttccagat ggcgcgaatg
     6841 cgtgcgctgg agctggcgcg cccactgttg cgcagcacca acaacggcat tacggcggtg
     6901 attggcccgc agggtgagat tcaggcgatg atcccgcagt tcacccgcga ggtgttgacc
     6961 actaatgtga caccgaccac cggactcaca ccgtatgcac gtaccggcaa ctggccgctg
     7021 tgggtgctga cggcgctgtt tggttttgcc gctgtgctga tgagtctgcg agcacgtaaa
     7081 cgttgatgtg cctgatgtat cctgcatgag caaaacgtac tttctcatta agctttgggg
     7141 catggttatc atgccccttt ttcttacggt tcagggatac aagccacatt gccatattgg
     7201 ggatgacgaa taattgcctg cggatcaagc gagcgcgtcc tgtccatttg gatcaacccg
     7261 ttcttcgcca tgacaaatat ttttctacca tccgctgaaa aacgaaggtg attaacgtag
     7321 ctggcaggat aaacgccaat aatctgcccg gcattaatat tgagcaggat gacataacct
     7381 tgcagtccat atgacaccaa cgctaaatat tgaccgtccg ggctaatacc ctcaacggaa
     7441 taaacgctcc tgctacacca ttgcgtcata atgctggttt gttgatcccc tatgcttata
     7501 cgtgaaatcc cctgactatc ggcaaaaata acctcgccgt tttcaggtcg aaaacgcatc
     7561 gccgatatcg ttccacgcgc atcacctgcg ggaaagtctt ctttctgatg cgtgatggta
     7621 ttgatccgca cgatgttacc tctgccttct cccggaacca gtaatgttct ttcatccggg
     7681 gaaagtgcca taacccaggc gcctggttta ccgctcgtcc ccgtcccgtc gtatttctcc
     7741 agcgggatat ccgccacatg ctgataagcc accagatcaa tggctgacac actattactg
     7801 gtgcgattca tcacccaggc ttttgtgcca tcacgcgaga ggataagact gtcaggatgt
     7861 gcaccggtgg taatcgactg aataatctcc cctgtcgcca cgttaatgac cgataacgca
     7921 ttcgcttcaa atgaagtcgc ataaatcaac ttttcatccg ggcttaatgc cagcgatctg
     7981 acgccctgat ctttacagcc accacaatgt ttgactgact tttctttcgc tatgggcgct
     8041 gtaaaggtat gcaggatttt cttttgtccg aggtcgaaaa caacaatgct gttggtgtct
     8101 tcaattgcgg catacaacgt attaccatcc cgactgatcg ccatatcatg gatatcggca
     8161 atctcagcga gcaaatcacc actggcctgt tcacgactta ccggagcgga taatgtttcc
     8221 ctgagggcgt tgcgttcctc cgctaactgc tgcttttttt gccgtcgctc ttgttcaatc
     8281 tcctgtggat aaaacgcttc acgcaggctt tgcctgactt gtaaaactga ctcatccatc
     8341 tgctgctgcg caagccagat agccccggtc agaagaagac tgcccgcaac aataatcccg
     8401 ccttccgtaa cgagtcggtt ttgcccagat aaacgcgcgc tcagccaacc caacgcgcca
     8461 cccgcaatca ggccgccaat gtggcaagcg ttatctattc ctgtttgccg ggcaccgtac
     8521 aacagtgtca gcgccaccat acccaacaga ggaaatactc gccgctggtt tttatggtat
     8581 gtgcccgtac ctgaagcaaa ctgtgttgct atcgctgcac cagctattcc cagaatcgcc
     8641 ccggatgccc caacgctgat gactatctgc tcactttcgc gtaacgcata acaggcgctg
     8701 atgagcccac caaagacgcc ggagaataac caggtaatca ggagtcgcca tttccccaga
     8761 atctgttccg ccacgcctcc cacgaccagg aatgcaaaca tattcatcag cagatgagaa
     8821 acactactgt gcagaaagat actgctcaat aagcgccagg gttcacccga caaagtaaga
     8881 ggcgcaacgt ttgcgccgag atggataagt gcggattgat cgacctcttc ataactcatc
     8941 cattgtgcga gataacaaaa tatcccaata cagagtgcaa aaaggataag ggttattgcg
     9001 ggtaattgaa catttaacgg cttaaccgaa gatgcagaca taaggtgttt cttccttgaa
     9061 aagacaggta aaaagcattt ttcccgtgtg cagttatcat cccggcaaac gtcccatgcc
     9121 gaaaagataa ttctgtccga aatatgactt tttcagccta aaattacaat cgtaattaat
     9181 ttgcccctaa gtattttttg gcatgtaagt tgctttattt actgtgtaag cgatgaaatc
     9241 agccgcgacg caaccaggtt gcaccaccac aaatcagcgg tagcaccaaa aaggtgcggt
     9301 ttaagaattt tgcttcggaa tggtgcggcg catctcgcaa aaacaaacaa taaaacagca
     9361 atatctttac atttagccaa actaaatgtt acctaacagg cacaacactg cacaataaag
     9421 ttgcagacga taacaacaca aacactcaca acgggtatcc atgcgttctt aacgcagaag
     9481 ataaaggagt tggatatgca attacgtaaa cctgccacag caatcctcgc cctggcgctt
     9541 tccgcaggac tggcacaggc agatgacgcc gccccggtag cgggcagtac gctggacaaa
     9601 atcgccaaaa acggtgtgat tgtcgtcggt catcgtgaat cttcagtacc tttctcttat
     9661 tacgacaatc agcaaaaagt ggtgggttac tcgcaggatt actccaacgc cattgttgaa
     9721 gcagtgaaaa agaaactcaa caaaccggac ttgcaggtaa aactgattcc gattacctca
     9781 caaaaccgta ttccgctgct gcaaaacggc acttttgatt ttgaatgtgg ttctaccacc
     9841 aacaacgtcg aacgccaaaa acaggcggct ttctctgaca ctattttcgt ggtcggtacg
     9901 cgcctgctga ccaaaaaggg cggcgatatc aaagattttg ccgacctgaa agacaaagcc
     9961 gtagtcgtca cttccggcac tacctctgaa gttttgctca acaaactgaa tgaagagcaa
    10021 aaaatgaata tgcgcatcat cagcgccaaa gatcacggtg actctttccg caccctggaa
    10081 agcggtcgtg ccgttgcctt tatgatggat gatgccctgc tggccggtga acgtgcgaaa
    10141 gcgaagaaac cagacaactg ggaaatcgtc ggcaagccgc agtctcagga ggcctacggt
    10201 tgtatgttgc gtaaagatga tccgcagttc aaaaagctga tggatgacac catcgctcag
    10261 gtgcagacct ccggtgaagc ggaaaaatgg tttgataaat ggttcaaaaa tccaattccg
    10321 ccgaaaaacc tgaacatgaa tttcgaactg tcagacgaaa tgaaagcact gttcaaagaa
    10381 ccgaatgaca aggcactgaa ctaattacaa gaaccagggg cggaaattcc agccctctcg
    10441 attgttacgt agcacggaca gactatacgc ctgatggtcg ttccccatcg ggcctgaaaa
    10501 ccgcaatacg ctgggtaaca atcttcgagg gtagcagtta acgctgctac cctctttttt
    10561 ctggagtaga tttatgtcta tagactggaa ctggggtatt tttttacaac aagccccgtt
    10621 cggcaacacc acctatcttg gttggatctg gagtggtttt caggtgacga tcgctttgtc
    10681 gatctgcgcc tggattatcg ctttcctcgt cggttcattt ttcggcattt tacgtaccgt
    10741 tccaaaccgt tttctctccg gtctgggtac gttgtatgtc gaactgttcc gcaacgtgcc
    10801 gttgattgtg caattcttta cctggtatct ggtgatcccg gagctgttgc cggagaaaat
    10861 cggcatgtgg tttaaggccg agctggatcc caatattcag tttttccttt catccatgct
    10921 ctgcctgggg ctgtttaccg ccgcccgtgt ttgcgaacag gtacgcgccg ctattcagtc
    10981 gctcccgcgt gggcagaaga atgccgcgct ggcgatgggc ctgacgctac cgcaggctta
    11041 ccgctatgta ctgctgccta atgcttatcg cgttatcgtc ccgccgatga cctccgagat
    11101 gatgaacctg gtgaaaaact ccgccatcgc ctcgactatc ggtctggtgg atatggcagc
    11161 gcaggcgggt aaattgctcg actactcggc tcacgcctgg gagtcgttta ccgccattac
    11221 gctggcgtat gtattgatta acgcggttat catgctggtg atgacgctgg ttgaacgtaa
    11281 agttcgcctg cccggcaaca tggggggcaa ataatgtacg agtttgactg gagttccatt
    11341 gttccttccc tgccatatct gctcgacggg ctggtgatca cgctgaaaat caccgtcacg
    11401 gcagtcgtga ttggtatttt gtggggcacc atgctggcgg tgatgcgctt gtccagcttt
    11461 gcgcccgtag cgtggtttgc caaagcctac gttaacgtat tccgctcgat tcctttagtt
    11521 atggttttgc tgtggtttta cctgatcgtg ccgggttttc tgcaaaacgt gctgggatta
    11581 tcgccaaaaa atgatatccg tttaatttcg gcgatggtgg cgttttcgat gtttgaagcg
    11641 gcctactatt cagagattat ccgtgctggt attcaaagta tttctcgtgg tcagtcgagc
    11701 gccgcgctgg cgttgggaat gactcactgg cagtcgatga aactgattat tctgccgcag
    11761 gcgttccgcg cgatggtgcc gcttctgctc actcagggca tcgtactgtt ccaggatacc
    11821 tcactggtgt atgtgttatc tctggccgat ttcttccgta ccgcctcaac cattggtgag
    11881 cgtgatggta cgcaggttga gatgatcctg tttgccggat ttgtttattt cgttattagt
    11941 cttagcgcgt cgttgttggt cagctacttg aaaagaagga cagcataatg attaccctga
    12001 aaaatgtttc aaaatggtat ggtcactttc aggtgctgac cgactgctca accgaagtga
    12061 aaaaaggcga agtggtggtg gtttgcggcc cgtctggctc cggcaaatca acgctgatta
    12121 aaaccgtcaa cggcctcgaa ccagtgcagc aaggtgaaat caccgtcgat ggtatcgtgg
    12181 ttaatgacaa gaaaaccgat ctggcaaagc tgcgttcccg cgtcgggatg gtgttccagc
    12241 attttgagtt gttccctcat ctgtcgatta tcgaaaacct gaccctggcg caggtgaaag
    12301 tgcttaaacg cgataaagcg ccggctcgtg aaaaagcatt gaaattgctg gagcgcgtgg
    12361 gactttccgc acatgccaat aaatttccgg cgcagctttc cggcggtcag cagcagcgtg
    12421 tggcgatcgc tcgcgcattg tgtatggatc ctattgcgat gctgttcgac gaaccgacgt
    12481 cggcgctgga tccggagatg atcaacgaag tgctggacgt gatggtggaa ctggcgaacg
    12541 aaggaatgac catgatggtg gtgacccacg aaatgggctt tgcccgcaaa gtggcgaatc
    12601 gggtgatctt tatggatgag ggtaaaattg tcgaagactc gccgaaagac gctttcttcg
    12661 atgatccgaa atcggaccgc gcaaaagact tcctcgcgaa aatcctgcat taatcactct
    12721 ggcgcgcata cccaagtgcg cgccatctca cgctttatcg tttcgcccct cgtatctgtt
    12781 acatcctggc gttacccttg tcgcaaagaa gcacacaaca aggagcaaca atggcactgc
    12841 caattctgtt agattgcgac ccaggtcatg acgacgctat cgcaatagtt ctcgccctcg
    12901 cctcaccaga gcttgatgtc aaagcaatta cgtcttccgc cggaaaccag acaccagaaa
    12961 aaaccttacg caatgttctt cgtatgctga ccttgctcaa tcgcaccgat attccggtag
    13021 caggcggcgc ggtaaaaccg ttaatgcgtg agttgattat cgcggacaat gtgcacggcg
    13081 aaagcggtct cgacggcccg gcattaccgg aaccggcgtt cgcaccgcaa aactgtacgg
    13141 cggtagagct aatggcgaaa acgctgcgtg aaagtgcgga acctgtcacg attgtgtcta
    13201 ccggaccaca aactaacgtt gccttgctgc tcaatagcca tccggaactg catagcaaaa
    13261 ttgcccgtat cgtgattatg ggcggcgcaa tggggcttgg taactggacg cctgcggctg
    13321 aatttaatat ttacgttgac ccggaagcgg cagaaattgt cttccagtca gggatcccgg
    13381 tggtgatggc cggtctggat gttactcata aagcacaaat ccacgttgaa gacaccgagc
    13441 gtttccgcgc gattggcaac cctgtttcaa ccattgttgc cgaactgctg gatttcttcc
    13501 tcgaatatca taaagacgaa aaatggggct ttgtcggtgc accgctgcat gacccatgca
    13561 ccatcgcctg gctgttgaaa cccgagttgt ttaccactgt tgagcgctgg gttggcgtgg
    13621 aaacacaggg gaaatatagc cagggtatga cggttgttga ttattattat ctgactggca
    13681 ataaaccgaa tgccactgta atggtcgatg ttgatcgtca gggctttgtt gatttactgg
    13741 ctgatcgtct gaaattttac gcttaacaca cgtcattgat taagatcacc acgcgttacc
    13801 tgggtggtct taatctgttt atctcttttt ctttcaagat ataaatgcaa tggataatgc
    13861 agaactcgcc attggtatcg atctcggcac taccaatagt ttaattgccg tctggaaaga
    13921 cggtgccgcg caattaattc caaataagtt cggtgaatat ttaacaccat ccataattag
    13981 catggatgaa aataatcata ttttagtcgg aaaaccggct gtatcacggc gtacttcgca
    14041 tccggataaa acggcagcgt tatttaaacg tgcaatgggc agtaatacca actggcggtt
    14101 aggcagcgac acatttaacg cgccagaact gtcctctttg gtattacgct cattaaaaga
    14161 agatgccgaa gaatttctgc aacgtccgat taaagatgtg gtgatctccg ttccggctta
    14221 tttcagcgat gaacaacgca agcatacccg tttagcagcg gagttagccg ggttaaatgc
    14281 ggtacgctta attaatgaac ccacagcagc tgcgatggca tatggcctgc atacgcaaca
    14341 aaatacccgc tcgctggttt ttgatctcgg tggcggcacg tttgacgtca cggtgctcga
    14401 atacgccacg ccggtgattg aagttcacgc ctccgctggc gataacttcc tcggtggcga
    14461 agattttacc catatgttgg tcgatgacgt tttaaagcgc gcggatgtcg ccaggaccac
    14521 gcttaacgag agtgaactgg cagccttgta cgcctgtgtg gaagcggcaa aatgtagcaa
    14581 tcaatcgcca ttgcacattc gctggcagta ccaggatgaa acgcgggagt gcgaatttta
    14641 cgagaacgaa ctggaagatt tgtggttgcc gctgctcaat cgcttgcgag tgccgattga
    14701 acaggcgttg cgcgatgcac gtctgaagcc gagtcaaatc gacagtctgg tgctggttgg
    14761 cggcgcgtca caaatgccgc tggtgcagcg aatcgccgtg cgtctgtttg gcaaattacc
    14821 gtatcaaagt tacgacccga gcaccattgt cgcgctgggc gcagcaatcc aggccgcctg
    14881 ccgcttacgc agtgaagata ttgaagaggt gatcctcact gatatttgcc cttactcgtt
    14941 gggcgttgaa gttaaccgcc agggcgtttc cggcattttc tcgccaatta ttgaacgaaa
    15001 caccacagta cccgtgtcgc gtgtagaaac ttactcgacc atgcacccgg aacaggattc
    15061 aattacggtt aacgtctatc agggagaaaa ccacaaagtt aaaaataaca ttctggttga
    15121 atccttcgat gtgccgttga agaaaaccgg ggcttatcag tcgattgata ttcgctttag
    15181 ttatgatatc aacggcttgc ttgaagttga cgtgcttctg gaagatggca gcgttaagtc
    15241 cagagtcatt aatcatagcc cggtaacatt gagcgcgcag cagattgaag agagtcggac
    15301 gcggttatcc gcattgaaaa tttatccgcg cgatatgctc atcaaccgca cctttaaggc
    15361 caaactggaa gagttgtggg cgcgggcgct gggtgacgag cgagaagaga ttggccgggt
    15421 gatcaccgat tttgatgcgg cgttgcagtc aaacgatatg gcccgcgtcg atgaggtcag
    15481 gcggcgggcg agcgtttatt tagccattga gacctcataa tcacggctgc cggatgcggc
    15541 gtaaatgctg catccggcat cggcgcaaaa aacacatcgt caactaaaca acatcgcgat
    15601 tttgccgaga gcataaccta taaccagcac cgttaaactg attttgataa tgctggtaat
    15661 gctctgtggt ttttcaccct catcattttt ttcttcatgg ttttcaggtg ttggctcatc
    15721 gacatcttca tcctccggct cgagttttac tttcgtcaac agcatccggg tgataatggc
    15781 ctctaatgga tgagcatctc cgccttccag ccttgtatta agacgggcca gcatctcttg
    15841 tttcggaaac gcttcaagta ctacctgttc cgctacccga tacaaatcca gtaacggtga
    15901 atcttcttct gtctcgctac cgactctcga tttccaccac gcccatgctt tgcgtttgaa
    15961 gaataacgac tcaataaacg attgacctaa cggcgataat tttccgctat gtaaaatttc
    16021 cgcccataac agccgcgtcc gggcgctctc accaggaaca tatttcagcg gttgaccttg
    16081 cgcatctacc atgctccgcg cttcgataac catcactaat aacgcgaaat aatccgggca
    16141 atgactcttg ctccactgca acaacaaatt atcagcttgt gtagatgggt aactttcccg
    16201 gtacgcgcag agatcggcaa gcaggctttc cccctcgccg cagtacaacc tttgagcaca
    16261 caagtaatat cgggcatctt cgctttctgg ttcttccatt tgccactgtt tggctacagg
    16321 aatgagttcc gccatacctg tttgcaccga gctgtaccag cgcaacagtt tgcgatgtaa
    16381 ctttgcatca tcaggaatga accacggacc ttccatcgcc aaaaacgcag tgacgtagtc
    16441 aggatggtaa cggcagcaac gttccagcgc gaagtaatac tcaacagtct ggttctgcaa
    16501 cgcaacggga tattccagaa ggctaaggaa atcgaaacaa tcaccagcct gaatggcctc
    16561 aagaaaagcc tccctttctt cctcatccat tccttcgctg tcattaaacg aatgccagtt
    16621 caaacgctct gccagcaaag aagcacaatt taatgaaaga tatcgcgctt ctatagcgat
    16681 tgcacacagc ggccagcgta attgatcgac atcctccatg ttccaggtat ttaattgctg
    16741 aataaatttc tgccaggcgg agggctgaaa acgatcactt tctgaatcca gtaatgtcct
    16801 gaatgcacgc agtatttcat gttcagcggc ggcatctttt tcttcatcat ctgcttcctc
    16861 gacaggattt accgccagtc gcagcgcctc ttcataggcc tggcgtaatg ctttaaaccc
    16921 ctgcggatcg gtttcgggat gacataacgg taagcgagca agataagcct ggcggataat
    16981 gtctatttgc gtcgtgcttt caatttcgag gatttgccaa catgttttca taggtcgctc
    17041 acatccttaa gcgttaccgg gcattcaggc tggacagtta atggctgcca gggaagcgtg
    17101 gcatagaaac gatcgcttcc cgctgccagc tcttcgaaca tccgactccc ggcgctatcg
    17161 tatttgtaca gggttagcgc ctcgcgtagc gaagtgttgt cttcgcactg agaagattgc
    17221 cagtagagac gtcctaacga ataggcggaa aaatagtgca tccagctgtg atagtaatgg
    17281 tgagctcgta catagacgcg cgattgcagc cataaactat cttcttccgt cagccagttg
    17341 ttgagcacac cgacccgtga cagaaacccc attcgaacat aatcccaggc tttgattccc
    17401 ccttctccac agcacatagc ggtttgggca acgaattggg tataaatcaa ccctctctcc
    17461 gagccaccag caattaatgc tttccactct tcaggggaag agcgatgcca tgtcagatat
    17521 aagccagcta aatcattggc atgaccatca tcagtcatct gataaatagt ctgaattaaa
    17581 tcatcacgat tatttattcc ccaggatgat gagagatcga attcttttat accggtatac
    17641 atttttggcg agtcatgcgc gggtttgcaa ccctgattaa gtatttccat gggcgcagaa
    17701 agcgcaaaaa gaagatattg ttcttcctta ttcatttgtt aataatccct taagtgcatt
    17761 aactgactac tttttattat tgatgagtat aaacttgacg ctttcaaaat aaaaagaaaa
    17821 tcgaagtatt cacatatgaa taaaaaatta atgtatatat tcgcaatatt tatagttgca
    17881 gcaattacct gtattagcca acccaagaaa acaacgttgc gtgataaagc catggtgaat
    17941 tatgcctttg attatttaag ctcaccaggc agtctaccgt taaccacggc agccacggag
    18001 ctttccgcga ttcatggtca ctcaacatcg caatatcgcc ttggcgaatt ttatcttcat
    18061 ggtagcgacg gtaaaccact ggattataca caggcgagat actggtatga gcaatcagca
    18121 gaacaggaaa atccgcgcgc acaaagcaaa ctggggtgga tctacctgaa aggcctggga
    18181 gtcaaacccg atacccgtaa agcaattctc tggtataagg aagcagctga acaagggtat
    18241 gctcatgctc aatatacttt gggtttgatc tacagaaatg gcactggtat taatgttaac
    18301 cattatgaat ctcaaaaatg gttaaaactg gccgccaaac aacattacaa aaatgcggaa
    18361 agattacttg ccgggcttcc cgcacattaa cgtcgactgt caaccgaaca gatggagtat
    18421 tttccctatc aaaccagcaa agataaaaat atagaaaata attttaatga tgcccagaca
    18481 gcctggccca ccatcgtcaa cgggcattgg ctgcggttgc ggctccggtt caacagtttg
    18541 cttctcggta aaattcgccg cctgaattaa taatcgacga ataattaatg cttccagtgg
    18601 acaacgatct tctgcatcaa ggcggctcac aatcggcatt aatgattctt cggttggttg
    18661 gttcgcctgc actaattgtt tggcaactaa atataatggc cataagggat gttctgtatc
    18721 acgcgtgagt gagatccgcg gcttacgtcc tttgtgcaaa accatctcga ccagtgaacg
    18781 ccccagagca gagagttttt catcgctgag tatttcgtat aaatgaaaac gcgtacgggc
    18841 gctgtcgccg gggatataaa gtagcggttt tccctgatcg ttaaccagtt cacgagcttc
    18901 aatcatcatc accactaacg ggtaataatc gacccgatgc tgacggcacc attgcaatat
    18961 taaagcatcc gcctgggtgg agggatactc gcgccagtag tcacaaagtt ctgccagcaa
    19021 gctttcgcct tctccacaat agacgcgttg tgcgtattca taataacgcg catcttcatt
    19081 atcagattca gcttcccgcc acgaccgggc gtaatccagg agttcgggaa ttcccaggcg
    19141 acctgcgcta taccagcgga gtaaatttct gtgcagtttt gcatcatcgg ggataatcac
    19201 tgcgcgatgt tgcgctaaat acaatgtcag ccattctgga tgcgatgacc aaatccgagc
    19261 gaacatttgg taaaaatcga tggtgtcatt ttgcacggca acgggcagat gcagaatggt
    19321 ctggaagtta aaaacattcc ccttcgcaat ggcatataaa aaggattcca gttcttcttc
    19381 gtctatttcc ccgacgtttt cctcctgcaa ccaccgcaat ctttctgcta ataacaccac
    19441 gcactcgaag gataaatggg cagtgttcat ggcgattgtg cacagcgacc agcgtaattc
    19501 atcaatctct tccatcgagc aataatttaa ttgctgaatg aatcgctgcc aggcggaggg
    19561 cagaaaacgt tcgctatcag aggcaagtaa cgcacgaaag gcgagcagaa tttcatgttc
    19621 tgctacctca tattcttctg gttgccaaac agatttagca ggcgactgcg caatccgtag
    19681 cgcctcctca tacgcctgac gaagttgttt aaaaccctgc ggatcggttt ctggatgaaa
    19741 ggacggtaac agcgccagat aagcgcggcg gataatatcg acgtcagtcg tttcctctat
    19801 ttcgagaatc ttccagcaat ttttcatagg tcgctcatat ccttaagcgt ttccgggcat
    19861 gcagaatagt aagccaatgg ttgccaggac aaggtagggt aatacgcatc atcactggca
    19921 aataattgat aaaacatatc attgccggaa tcgtcgtatt ctttacgcgc taagaattcg
    19981 cgtaataact gcagatgatc atcttcggga gactgccaat attgccgacc aaaggtataa
    20041 ccggcaaagt attgccgcca gttacgataa taacgtagag cccgtagatg aatgcgcgac
    20101 tggatccata gactttcttc ttcgctcaac cagttattaa gtacgcccat tcggcttaaa
    20161 aaacccatcc ggacataatc ccaggcttta attcctccct caccacagca ttcggcggtg
    20221 ctggcgacaa attgcgcata agcctgacct tgctcattta gttcagcaag atagtcacgc
    20281 cattcacatg gcgaataacg aaaccagcgg tgataaaacc ctgccaaccg agcggcatga
    20341 ccgttatcga tcattcggtg aattgtgcgc agcaggtcat cacgggcatc aattccccag
    20401 gaggaagaaa ggtcaaaaaa gcatgtacct aaatacattt tgggtgatga atgcgaaggt
    20461 aaacagcatt cattgcgtat ttccatcgga gtggaaagtg caaacaatat tttttgcgac
    20521 tccatgtcca tataatttat ccttaaatat tcattaaatg aatattagcc gcattgcgag
    20581 gctcgtttat ttatactttt ctgacgcgac ataatacgca taaaataagg cttacgcaaa
    20641 aatggaacac ataaaaatat aatatgtttt atctgcaacc gtaaggaaat gataatgatt
    20701 ttcacgtcaa gttgctgcga taatttatca atagatgaga ttatcgaacg tgctgaaaaa
    20761 ggcgattgcg aggctcaata tattgttggg ttttattata atcgcgatag cgcaattgat
    20821 tctccggacg acgaaaaagc cttttactgg ctgaagctgg ccgctgagca aggtcattgt
    20881 gaagcacagt attccttagg gcaaaagtat accgaggata aaagccgtca taaagataat
    20941 gagcaagcca tcttctggct gaaaaaagct gccctacaag gccatacttt cgcttccaac
    21001 gcccttggct ggacactgga tcgtggagaa gcccccaatt ataaagaagc ggttgtctgg
    21061 tatcagatag ccgcggagag cggaatgtct tatgcgcaaa ataatcttgg gtggatgtac
    21121 agaaatggca acggagtcgc aaaagactat gcgctggcat ttttctggta caaacaagct
    21181 gcattacaag gccatagtga cgcgcaaaac aatctggccg atctttatga agacggaaaa
    21241 ggcgttgctc aaaacaagac actcgccgca ttctggtatt tgaaaagcgc acagcagggt
    21301 aatcggcacg cccagtttca aattgcatgg gattataacg ctggcgaagg ggtggaccag
    21361 gactataagc aagcgatgta ctggtatctg aaggctgccg ctcaggaaag cgtcggcgct
    21421 tacgtcaaca tcggttatat gtataaacac ggacaaggcg ttgagaaaga ttatcaggct
    21481 gcctttgaat ggtttacgaa agccgctgaa tgcaatgacg ccactgcctg gtataacctg
    21541 gccattatgt atcactacgg agaaggaaga cctgtcgatc tccgacaggc tctcgacctg
    21601 tatcgtaaag ttcagtcatc cggaaccaga gatgtcagtc aggaaattcg tgagactgaa
    21661 gatttactgt agagataaaa acaagggccg gggaatttca ttcggcccat attctcttta
    21721 ttgctgtgcg aaatcagact attacggctc aaacgggcgt ctctggaact ggtcatgacc
    21781 acatttcggg catagcgtca gcacttccgg tgtgtagatc gggagatgga agtgacattt
    21841 ctcgcagacc agatttccca gcccgaccac ttctccgctg tgataaaccc catgatgatt
    21901 gaggtcctgg aaaacttcgc gccattcaag ctgcgtttta tcggtgatat ctgccagctc
    21961 ctgccataag ctttctttaa tcacccgtat aaagacgctg tcagattctt ctttcaggct
    22021 ctcttcatag ctcatggcga actcttccag gtcacgtctt acagctcgcg tcagctcatc
    22081 gacctcggtt cgcgttaact cccctgtttt tattacgcgc tcgcgcgcct gttccaccag
    22141 tgcgtcgata tcacgttcgc cattgcgcag gcgttcgctc agtgacgcga ccagttcacg
    22201 gtaatattga gcaaccttgt tcatcgtttc atctcccggg tcgttaactg actataataa
    22261 tagacgttct ttgttccttg ctttgctaat acgcccacaa actctgtaaa ttaatgtatg
    22321 aataatccgg gcatcatttc aacgtcgagt gcgcgaaagg ctgttttgac gcggacgttt
    22381 gggctatgct atgcggatct gaaaaaccac ctcaacgcta catttgtagc cgtattgaaa
    22441 acaggaccac tggctgccat gcaagagcaa taccgcccgg aagagataga atccaaagta
    22501 cagcttcatt gggatgagaa gcgcacattt gaagtaaccg aagacgagag caaagagaag
    22561 tattactgcc tgtctatgct tccctatcct tctggtcgac tacacatggg ccacgtacgt
    22621 aactacacca tcggtgacgt gatcgcccgc taccagcgta tgctgggcaa aaacgtcctg
    22681 cagccgatcg gctgggacgc gtttggtctg cctgcggaag gcgcggcggt gaaaaacaac
    22741 accgctccgg caccgtggac gtacgacaac atcgcgtata tgaaaaacca gctcaaaatg
    22801 ctgggctttg gttatgactg gagccgcgag ctggcaacct gtacgccgga atactaccgt
    22861 tgggaacaga aattcttcac cgagctgtat aaaaaaggcc tggtatataa gaagacttct
    22921 gcggtcaact ggtgcccgaa cgaccagacc gtactggcga acgaacaagt tatcgacggc
    22981 tgctgctggc gctgcgatac caaagttgaa cgtaaagaga tcccgcagtg gtttatcaaa
    23041 atcactgctt acgctgacga gctgctcaac gatctggata aactggatca ctggccagac
    23101 accgttaaaa ccatgcagcg taactggatc ggtcgttccg aaggcgtgga gatcaccttc
    23161 aacgttaacg actatgacaa cacgctgacc gtttacacta cccgcccgga cacctttatg
    23221 ggttgtacct acctggcggt agctgcgggt catccgctgg cgcagaaagc ggcggaaaat
    23281 aatcctgaac tggcggcctt tattgacgaa tgccgtaaca ccaaagttgc cgaagctgaa
    23341 atggcgacga tggagaaaaa aggcgtcgat actggcttta aagctgttca cccattaacg
    23401 ggcgaagaaa ttcccgtttg ggcagcaaac ttcgtattga tggagtacgg cacgggcgca
    23461 gttatggcgg ttccgggtca cgaccagcgc gactacgagt ttgcctctaa atacggcctg
    23521 aacatcaaac cagttatcct ggctgctgac ggctctgagc cagatctttc tcagcaagcc
    23581 ctgactgaaa aaggcgtgct gttcaactct ggcgaattca acggtcttga ccatgaagcg
    23641 gccttcaacg ccatcgccga taaactgact gcgatgggcg ttggcgagcg taaagtgaac
    23701 taccgcctgc gcgactgggg tgtttctcgt cagcgttact ggggcgcgcc gattccgatg
    23761 gtgacgctgg aagacggtac cgtaatgccg accccggacg accagctgcc ggtgatcctg
    23821 ccggaagatg tggtgatgga cggcattacc agcccgatta aagcagatcc ggagtgggca
    23881 aaaactaccg ttaacggtat gccagcgctg cgtgaaaccg acactttcga cacctttatg
    23941 gagtcctcct ggtactatgc gcgctacact tgcccagagt acaaagaagg tatgctggat
    24001 tccgaagcgg ctaactactg gctgccggtg gatatctaca ttggtggtat cgaacacgcc
    24061 attatgcacc tgctctactt ccgcttcttc cacaaactga tgcgtgatgc aggcatggtg
    24121 aactctgacg aaccagcgaa acagttgctg tgtcagggta tggtgctggc agatgccttc
    24181 tactatgttg gcgaaaacgg cgaacgtaac tgggtttccc cggttgatgc tatcgttgaa
    24241 cgtgacgaga aaggccgtat cgtgaaagcg aaagatgcgg caggccatga actggtttat
    24301 accggcatga gcaaaatgtc caagtcgaag aacaacggta tcgacccgca ggtgatggtt
    24361 gaacgttacg gcgcggacac cgttcgtctg tttatgatgt ttgcttctcc ggctgatatg
    24421 actctcgaat ggcaggaatc cggtgtggaa ggggctaacc gcttcctgaa acgtgtctgg
    24481 aaactggttt acgagcacac agcaaaaggt gatgttgcgg cactgaacgt tgatgcgctg
    24541 actgaagatc agaaagcgct gcgtcgcgat gtgcataaaa cgatcgctaa agtgaccgat
    24601 gatatcggcc gtcgtcagac cttcaacacc gcaattgcgg cgattatgga gctgatgaac
    24661 aaactggcga aagcaccaac cgatggcgag caggatcgcg ctctgatgca ggaagcgctg
    24721 ctggccgttg tccgtatgct taacccgttc accccgcaca tctgcttcac gctgtggcag
    24781 gaactgaaag gcgaaggcga tatcgacaac gcgccgtggc cggttgctga cgaaaaagcg
    24841 atggtggaag actccacgct ggtcgtggtg caggttaacg gtaaagtccg tgccaaaatc
    24901 accgttccgg tggacgcaac ggaagaacag gttcgcgaac gtgctggcca ggaacatctg
    24961 gtagcaaaat atcttgatgg cgttaccgtg cgtaaagtga tttacgtacc aggtaaactc
    25021 ctcaatctgg tcgttggcta agcgcgggag gaagcgtgcg atatctggca acattgttgt
    25081 tatctctggc ggtgttaatc accgccgggt gtggctggca tctgcgtgat accacgcagg
    25141 ttccttccac tatgaaggtc atgatcctgg actcaggcga tccgaacggg ccattaagcc
    25201 gtgcggtgcg taaccagtta cgtctgaatg gtgtcgagtt gcttgataaa gaaaccacgc
    25261 gtaaggacgt tccatccctg cgtttgggta aagtgagcat cgcgaaagat accgcatcgg
    25321 tattccgtaa cggtcaaaca gcagagtatc agatgatcat gacggtgaat gcgaccgtgt
    25381 tgatccccgg ccgtgatatc tacccgatta gtgccaaagt cttccgttcg ttctttgata
    25441 acccgcaaat ggcgttagcg aaagataacg aacaagacat gatcgtaaaa gagatgtacg
    25501 accgtgctgc cgaacagctg attcgtaagc tgccaagcat ccgtgctgcg gatattcgtt
    25561 ccgacgaaga acagacgtcg accacaacgg atactccggc aacgcctgca cgcgtctcca
    25621 ccacgctggg taactgatga ttcggttgta cccggaacaa ctccgcgcgc agctcaatga
    25681 agggctgcgc gcggcgtatc ttttacttgg taacgatcct ctgttattgc aggaaagcca
    25741 ggacgctgtt cgtcaggtag ctgcggcaca aggattcgaa gaacaccaca ctttttccat
    25801 tgatcccaac actgactgga atgcgatctt ttcgttatgc caggctatga gtctgtttgc
    25861 cagtcgacaa acgctattgc tgttgttacc agaaaacgga ccgaatgcgg cgatcaatga
    25921 acaacttctc acactcaccg gacttctgca tgacgacctg ctgttgatcg tccgcggtaa
    25981 taaattaagc aaagcgcaag aaaatgccgc ctggtttact gctcttgcga atcgcagcgt
    26041 gcaggtgacc tgtcagacac cggagcaggc tcagcttccc cgctgggttg ctgcgcgcgc
    26101 aaaacagctc aacttagaac tggatgacgc tgcaaatcag gtgctctgct actgttatga
    26161 aggtaacctg ctggcgctgg ctcaggcact ggagcgttta tcgctgctct ggccagacgg
    26221 caaattgaca ttaccgcgcg ttgaacaggc ggtgaatgat gccgcgcatt tcaccccttt
    26281 tcattgggtt gatgctttgt tgatgggaaa aagtaagcgc gcgttgcata ttcttcagca
    26341 actgcgtctg gaaggcagcg aaccggttat tttgttgcgc acattacaac gtgaactgtt
    26401 gttactggtt aacctgaaac gccagtctgc ccatacgcca ctgcgtgcgt tgtttgataa
    26461 gcatcgggta tggcagaacc gccggggcat gatgggcgag gcgttaaatc gcttaagtca
    26521 gacgcagtta cgtcaggccg tgcaactcct gacacgaacg gaactcaccc tcaaacaaga
    26581 ttacggtcag tcagtgtggg cagagctgga agggttatct cttctgttgt gccataaacc
    26641 cctggcggac gtatttatcg acggttgata tgaaatcttt acaggctctg tttggcggca
    26701 cctttgatcc ggtgcactat ggtcatctta aacccgtgga aacgctggcg aatttgattg
    26761 gtctgacgcg ggtcacaatc atccctaata atgttcctcc gcatcgtccc cagccggaag
    26821 cgaacagcgt gcagcgtaaa cacatgcttg aactggcgat tgccgacaag ccattattta
    26881 ctcttgatga acgcgagcta aagcgcaatg ccccctctta cactgcgcaa acactgaaag
    26941 agtggcggca ggaacaaggg ccggacgtgc cgctggcgtt tattattggt caggattcat
    27001 tgctgacctt tccgacctgg tacgaatacg aaacgatact cgacaatgca catttgatcg
    27061 tctgtcggcg tccaggttac ccacttgaaa tggcgcaacc gcaataccag caatggctgg
    27121 aagatcattt gacacataac ccggaagatc ttcaccttca gcctgccggt aaaatttatc
    27181 tggctgaaac gccgtggttt aacatctcgg cgaccatcat ccgcgaacgt ttgcaaaacg
    27241 gtgaatcgtg tgaggattta ttgccggaac cggtactgac ttacattaac caacaaggct
    27301 tgtatcgctg atacctgtcg ttacggaggg catgatgcga ctgtggttaa ttcgtcatgg
    27361 cgaaacgcaa gcgaatgtcg atggtctgta cagcggtcat gcgcccacac ccctgaccgc
    27421 acgcggtatt gagcaagcgc aaaatctgca tacgctgcta catggtgttt cctttgatct
    27481 ggttttatgc agtgaactgg aacgggcaca gcataccgcg cgactggttc tcagtgaccg
    27541 ccagctcccc gttcatatca tccctgaact caacgaaatg ttttttggcg actgggagat
    27601 gcgacatcat cgcgacctca tgcaagaaga tgccgaaaac tatagcgcgt ggtgcaatga
    27661 ctggcagcat gcaatcccca cgaacggtga aggatttcag gcattttcgc aacgtgtgga
    27721 acgctttatc gcaaggctta gtgaatttca gcactatcag aatattttag tcgtcagcca
    27781 tcagggtgta ctgagtctgt taatcgcccg tttaattggc atgcctgccg aggctatgtg
    27841 gcattttcgc gttgaccagg ggtgttggag caccattgat atcaaccaaa aattcgcgac
    27901 gctacgcgtc ctcaatagcc gtgccatcgg ggtcgagaat gcatgacttt tctgtttttt
    27961 tacgggtaag ccgcaacgac cattgacaga cccgggcagg ctgatattct ccgcagccag
    28021 acttttttcg ccagacacga ctttgtagaa attgttttac aaaaatggcg atgcaatctg
    28081 cggcgcgggg tgggatgata gcccactttc gaaagccgat tcggcgacaa ttgtcccgaa
    28141 atcgcctctg gttcaggtat actgacagac catttttatc tatttgattc acccaggggg
    28201 aaaacttgca gggtaaagca ctccaggatt ttgttatcga caaaattgat gacctcaaag
    28261 gtcaggacat catcgcctta gacgttcaag gcaaatccag catcaccgac tgcatgatca
    28321 tctgtacggg tacgtccagc cgtcatgtta tgtccattgc tgaccacgtt gtgcaggagt
    28381 ctcgcgcagc gggcctgtta ccgctcggcg tagaaggtga aaacagcgcc gactggattg
    28441 tcgtggattt gggcgatgtg attgtccatg tcatgcagga agagagccgt cgcctgtatg
    28501 aactggaaaa actctggagt taatgcgtga agctgcaact tgtcgccgtg ggaacgaaaa
    28561 tgccggactg ggtacaaacc ggttttaccg agtacctgcg tcgttttccg aaagatatgc
    28621 ccttcgagct gattgaaatt ccggccggaa aacgcggcaa gaatgcggac atcaagcgca
    28681 tactcgacaa agagggtgag cagatgttgg cggccgcagg caaaaaccgc attgtcaccc
    28741 tcgatattcc aggcaagccc tgggatacgc cgcagttagc cgctgagctg gaacgctgga
    28801 agctggatgg tcgcgacgtc agtctactga ttggcgggcc tgaagggttg tcgcctgcct
    28861 gtaaagcggc ggcggagcag agctggtcgc tgtcgacgct taccctcccc catccgctgg
    28921 ttcgcgtgct ggtcgcagag agtctgtacc gggcgtggag catcaccacc aaccatcctt
    28981 atcaccgtga gtgataaggg agctttgagt agaaaacgca gcggatgaaa ctacagaact
    29041 cttttcgcga ctatacggca gagtccgcgc tgtttgtgcg ccgggcgctg gtcgcctttt
    29101 tggggatttt gctgctgacc ggcgtgctta tcgccaacct gtataatctg caaattgttc
    29161 gctttaccga ctaccagacc cgctctaatg aaaaccgcat taagctggtg cctatcgcgc
    29221 ccagccgcgg cattatctac gaccgtaatg gtatccctct ggccctcaac cgcactatct
    29281 accagataga aatgatgcca gagaaagtcg ataacgtgca gcaaacgctg gacgctttgc
    29341 gcagcgtggt tgatctgacc gatgacgata ttgctgcatt ccgaaaagag cgcgcacgtt
    29401 cacaccgttt cacctctatt ccggtgaaaa ctaacctgac cgaagtacaa gtagctcgct
    29461 ttgccgtcaa tcagtaccgt tttccgggtg tcgaagttaa aggctataaa cgtcgttact
    29521 atccttacgg ttcggcgttg acccacgtca tcggctatgt gtcgaaaatc aacgataaag
    29581 acgtcgaacg cctgaataat gacggcaaac tggccaacta tgcggcaacg catgatatcg
    29641 gtaagctggg cattgagcgt tactatgaag acgtggtgca cggtcagacc ggttatgaag
    29701 aggttgaagt taacaaccgt gggcgtgtta tccgccagtt aaaagaagta ccaccgcaag
    29761 ccggacacga tatttacctg acgctggatc tcaaactcca gcaatatatt gaaacgctgc
    29821 tggcgggtag ccgcgcagct gtggttgtca ccgatccgcg tacaggtggg gtgctggcgc
    29881 tggtttccac gcctagttat gacccaaacc tgtttgttga cggtatctcc agcaaagatt
    29941 attccgcctt gttgaacgac ccgaatacac cgctggtgaa ccgcgccaca cagggggttt
    30001 atcctcccgc gtctacagtt aaaccctatg tggcggtttc ggcattgagc gccggggtga
    30061 tcacgcgcaa tacgacgctg tttgacccag gctggtggca actgccaggt tcggaaaaac
    30121 gttatcgtga ctggaaaaaa tggggccacg ggcgtctgaa tgtcacaaga tcgctggaag
    30181 aatctgcgga taccttcttc tatcaggtgg cctacgatat ggggatcgat cgcctctccg
    30241 aatggatggg taaattcggt tatggtcatt acaccggtat cgacctggcg gaagaacgtt
    30301 ccggcaacat gcctacccgc gaatggaaac agaaacgctt taaaaaaccg tggtatcagg
    30361 gtgacaccat tccggttggt atcggtcagg gttactggac agcgacccca atccagatga
    30421 gtaaggcact gatgatcctg attaatgacg gtatcgtgaa ggttccgcat ttgctgatga
    30481 gcaccgccga agacggcaaa caggtgccat gggtacaacc gcatgaaccg cccgtcggcg
    30541 atattcattc cggttactgg gagctggcga aagacggtat gtacggtgtt gctaaccgcc
    30601 ctaacggtac ggcgcataaa tactttgcca gcgcaccgta caaaattgcg gcgaaatctg
    30661 gtaccgctca ggtcttcggt ctgaaagcga acgaaaccta taatgcgcac aaaattgccg
    30721 agcgtttacg tgaccacaaa ctgatgaccg cctttgcgcc atacaacaat ccgcaagtgg
    30781 ctgtcgccat gattctggag aacggcggcg cgggtccggc ggttggtacg ctgatgcgcc
    30841 agatcctcga ccacattatg ctgggtgata acaacaccga tctgcctgcg gaaaatccag
    30901 cggttgccgc agcggaggac cattaatcat gacggataat ccgaataaaa aaacattctg
    30961 ggataaagtc catctcgatc ccacaatgct gctgatttta ctggcattgc tggtttacag
    31021 cgccctggtt atctggagcg ccagcggtca ggatattggc atgatggagc gcaaaatcgg
    31081 ccaaatcgcg atgggtctgg tcatcatggt ggtgatggcg caaattcctc cacgcgttta
    31141 tgaaggctgg gccccctatc tctatatcat ctgtattatt ttgctggtgg cggtagatgc
    31201 tttcggtgcc atctctaaag gtgctcaacg ctggctggac ctcggtattg ttcgttttca
    31261 gccgtcggaa attgccaaaa tagccgtacc actgatggtt gcgcgcttta tcaaccgcga
    31321 cgtttgcccg ccatcgttga agaacactgg catcgcgctg gtgctgatat ttatgcccac
    31381 gctgctggtg gctgcacagc ctgacctggg aacatcaatc ctcgttgcgc tttccggtct
    31441 gtttgtactg ttcctctctg gccttagctg gcgtctgatt ggcgtcgcag tagtgctggt
    31501 ggcggcgttc attccgattc tgtggttctt cctgatgcat gattaccagc gccagcgcgt
    31561 aatgatgctc ctggacccgg aatcagaccc actcggcgcg ggctatcaca ttattcagtc
    31621 taaaattgct attggctccg gcggattacg cggcaaaggc tggctgcacg gcactcagtc
    31681 acagcttgaa tttctccccg aacgccatac cgactttatc ttcgcggtac tggcggaaga
    31741 gctgggatta gtgggcattt tgattctgct cgctctctac attctgctga tcatgcgcgg
    31801 gctgtggata gccgccagag cgcaaaccac ctttggtcgc gtcatggctg gtggcttaat
    31861 gctgatatta ttcgtttatg tcttcgtaaa tattggtatg gtaagcggta ttctgccggt
    31921 tgtaggggtt ccgctcccac tggtcagtta tggaggatcg gcgctaattg tgctgatggc
    31981 tgggttcggg attgtaatgt caatccacac ccacaggaaa atgttgtcga aaagcgtgta
    32041 agaggtgcgc aatgcgtaag cagtggctcg ggatctgcat cgcggcagga atgctcgcgg
    32101 catgtacaag cgatgatggt cagcaacaga cggtaagtgt accgcagcct gcggtatgta
    32161 acggccccat agttgaaatt agcggggcgg atccgcgttt cgaaccactg aacgcgacgg
    32221 caaatcagga ttaccagcgc gacggtaaaa gctacaaaat cgtgcaggat ccgtctcgat
    32281 ttagccaggc gggactggcg gcaatctatg atgccgaacc aggcagtaac ctgacggcct
    32341 ctggcgaagc tttcgatccg acacagctga cggcggccca tccaacgctt ccgatcccca
    32401 gctacgccag aatcactaac ctggctaacg ggcgaatgat cgtggtgcgc attaatgatc
    32461 gcggccctta cggcaacgac cgcgttattt cgctttctcg cgcggcagct gaccgtctta
    32521 acacgtcaaa caacaccaaa gttcgtatcg atccgattat tgtcgcccag gatggttcgc
    32581 tttctggtcc tggtatggct tgtaccacag tcgccaaaca gacttacgcc ctgccagcac
    32641 ctcccgattt aagcggtggc gcgggaacaa gttcagtgtc tggcccgcag ggtgacattc
    32701 ttccggtcag taattcgacg ctaaaaagcg aagatccgac cggcgcgccg gtaaccagta
    32761 gcggtttcct cggcgctcca acgaccttag cgcctggtgt actggaaggc agcgaaccga
    32821 cgcctgcgcc acagcccgtt gttacagctc cgtcgacaac gcctgcaacc tcgcctgcaa
    32881 tggtgacacc gcaagccgcc tcgcaaagcg ccagcggcaa ctttatggtg caagtcgggg
    32941 ccgttagcga tcaggctcgt gcgcaacagt accaacagca actgggacag aagttcggcg
    33001 tccccggtcg cgtaactcaa aatggcgcgg tctggcggat ccagcttggc ccattcgcca
    33061 gcaaagccga agccagcacc ttgcagcaac gtttgcaaac cgaagcccaa ttacagtcat
    33121 ttattaccac cgcgcagtag cgtaaagcag gcatctgatg tgtcaatttc tgtaaatgac
    33181 gttaacaaag tcacgcggaa agtcagatgc ctgccggtag tgcatttgct atagtagggc
    33241 acttttttta attccatcac ggatgtcgta gttcagacca tgaataccat tttttccgct
    33301 cgtatcatga agcgcctggc gctcaccacg gctctttgca cagcctttat ctctgctgca
    33361 catgccgatg acctgaatat caaaactatg atcccgggtg taccgcagat cgatgcggag
    33421 tcctacatcc tgattgacta taactccggc aaagtgctcg ccgaacagaa cgcagatgtc
    33481 cgccgcgatc ctgccagcct gaccaaaatg atgaccagtt acgttatcgg ccaggcaatg
    33541 aaagccggta aatttaaaga aactgattta gtcactatcg gcaacgacgc atgggccacc
    33601 ggtaacccgg tgtttaaagg ttcttcgctg atgttcctca aaccgggcat gcaggttccg
    33661 gtttctcagc tgatccgcgg tattaacctg caatcgggta acgatgcttg tgtcgccatg
    33721 gccgattttg ccgctggtag ccaggacgct tttgttggct tgatgaacag ctacgttaac
    33781 gcactgggcc tgaaaaatac ccacttccag acggtacatg gtctggatgc tgatggtcag
    33841 tacagctccg cgcgagatat ggcgctgatc ggccaggcat tgatccgtga cgtaccgaat
    33901 gaatactcga tctataaaga aaaagaattt acgtttaacg gtattcgcca gctgaaccgt
    33961 aacggcctgt tatgggataa cagcctgaat gtcgacggca tcaaaaccgg acacactgac
    34021 aaagcaggtt acaaccttgt tgcttctgcg actgaaggcc agatgcgctt gatttctgcg
    34081 gtgatgggcg gacgtacttt taaaggccgt gaagccgaaa gtaaaaaact gctaacctgg
    34141 ggcttccgtt tcttcgaaac cgttaaccca ctgaaagtag gtaaagagtt cgcctctgaa
    34201 ccggtttggt ttggtgattc tgatcgcgct tcgttagggg ttgataaaga cgtgtacctg
    34261 accattccac gtggtcgcat gaaagatctg aaagccagct atgtgctgaa cagcagtgaa
    34321 ttgcatgcgc cgctgcaaaa gaatcaggtc gtcggaacta tcaacttcca gcttgatggc
    34381 aaaacgatcg agcaacgccc gctggttgtg ttgcaagaaa tcccggaagg taacttcttc
    34441 ggcaaaatca ttgattacat taaattaatg ttccatcact ggtttggtta aaaattgaac
    34501 acttgaaagt gtaatttccg tccccatata ctaagcatca gtaaaaaaac tcccgccttc
    34561 tggcgggagt tgctatttaa ttacgttacg ccggagctga catgaaaacc aaacttaacg
    34621 aactgcttga attccctact ccttttactt acaaagttat ggggcaggcg ttacctgagc
    34681 tggttgatca ggtggttgaa gtggtacagc gccatgcgcc aggtgactac accccaacgg
    34741 taaaaccaag cagcaaaggc aactaccact cggtatctat cactatcaac gccactcata
    34801 tcgagcaggt tgaaacactg tatgaagaac tgggcaaaat cgatattgtc cgcatggttc
    34861 tgtaactcgc ttctccgtta cccggctcct ggtcgggtaa ctcccctctc ctcgctgtga
    34921 tatacttttc ccccactttt actcattctc cacggagatg ccgttttgta tcaggataaa
    34981 attcttgtcc gccagctcgg tcttcagcct tacgagccaa tctcccaggc tatgcatgaa
    35041 ttcaccgata cccgcgatga tagtaccctt gatgaaatct ggctggtcga gcactatccg
    35101 gtattcaccc aaggtcaggc aggaaaagcg gagcacattt taatgccggg tgatattccg
    35161 gtgatccaga gcgatcgcgg tgggcaggtg acttatcacg ggccgggaca acaggtgatg
    35221 tatgtgttgc ttaacctgaa acgccgtaaa ctcggtgtgc gtgaactggt gaccttgctt
    35281 gagcaaacag tggtgaatac cctggctgaa ctgggtatag aagcgcatcc tcgggctgac
    35341 gcgcctggtg tctatgtcgg ggaaaagaaa atttgctcac tgggtttacg aattcgacgc
    35401 ggttgttcat tccacggtct ggcattaaac gtcaatatgg atctttcacc atttttacgt
    35461 attaatcctt gtgggtatgc cggaatggaa atggctaaaa tatcacaatg gaaacccgaa
    35521 gcgacgacta ataatattgt tccacgttta ctggaaaata ttttagcgct actaaacaat
    35581 ccggacttcg aatatattac cgcttaattc catacctcaa tggcccaatt tacactgggt
    35641 cattactcat aatacctgct aatgctttac atctccttcg cgtttgtata ttttctttat
    35701 cacttgcaga aatgcggtgc cacgccttgc tccgtaactc accccattga ttaacctatt
    35761 gaaatagttg attatggtga gcaaaagcgt tccgttccaa ttagacataa gattattgta
    35821 attttttaaa tattattttt ccatgaataa aattggagta agtgcg
//
LOCUS       DAZUDJ010000052        35246 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.052, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000052 DAZUDJ010000000
VERSION     DAZUDJ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35246
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.052"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(148..291)
                     /gene="ypaB"
                     /locus_tag="ACHY1N_003298"
     CDS             complement(148..291)
                     /gene="ypaB"
                     /locus_tag="ACHY1N_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001753443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YpaB"
                     /protein_id="HFS4045549.1"
                     /translation="MALLQVHNFVDNSGRKKWLSRTLGQTRCPGKSMGREKFVKNNCS
                     AIS"
     gene            419..2704
                     /gene="nrdA"
                     /locus_tag="ACHY1N_003299"
     CDS             419..2704
                     /gene="nrdA"
                     /locus_tag="ACHY1N_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1a ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFS4045550.1"
                     /translation="MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPAL
                     YDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYYLAKHGVRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLV
                     GIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLVPSIQDDGCESGACKI"
     gene            2851..3981
                     /gene="nrdB"
                     /locus_tag="ACHY1N_003300"
     CDS             2851..3981
                     /gene="nrdB"
                     /locus_tag="ACHY1N_003300"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ia ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFS4045551.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDL
                     FVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDAEVDTDDLSNFQL"
     gene            3981..4235
                     /gene="yfaE"
                     /locus_tag="ACHY1N_003301"
     CDS             3981..4235
                     /gene="yfaE"
                     /locus_tag="ACHY1N_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HFS4045552.1"
                     /translation="MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGS
                     CRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM"
     gene            complement(4289..4939)
                     /gene="inaA"
                     /locus_tag="ACHY1N_003302"
     CDS             complement(4289..4939)
                     /gene="inaA"
                     /locus_tag="ACHY1N_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide kinase InaA"
                     /protein_id="HFS4045553.1"
                     /translation="MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKL
                     YVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALL
                     VTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIY
                     VKTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM"
     gene            complement(5019..5123)
                     /locus_tag="ACHY1N_003303"
                     /pseudo
     CDS             complement(5019..5123)
                     /locus_tag="ACHY1N_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311148.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5121..5360
                     /locus_tag="ACHY1N_003304"
                     /pseudo
     CDS             5121..5360
                     /locus_tag="ACHY1N_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311149.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(5402..6478)
                     /gene="glpQ"
                     /locus_tag="ACHY1N_003305"
     CDS             complement(5402..6478)
                     /gene="glpQ"
                     /locus_tag="ACHY1N_003305"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFS4045554.1"
                     /translation="MKLKLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLP
                     EHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRY
                     YAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNH
                     STGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRI
                     KNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADG
                     IGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDAL
                     YNKAGVNGLFTDFPDKAVKFLNKE"
     gene            complement(6483..7841)
                     /gene="glpT"
                     /locus_tag="ACHY1N_003306"
     CDS             complement(6483..7841)
                     /gene="glpT"
                     /locus_tag="ACHY1N_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015169 - glycerol-3-phosphate
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015794 - glycerol-3-phosphate
                     transmembrane transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HFS4045555.1"
                     /translation="MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFFYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTI
                     ATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRN
                     GG"
     gene            8114..9742
                     /gene="glpA"
                     /locus_tag="ACHY1N_003307"
     CDS             8114..9742
                     /gene="glpA"
                     /locus_tag="ACHY1N_003307"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0046174 - polyol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HFS4045556.1"
                     /translation="MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLS
                     FQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAE
                     YADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYN
                     EIDDNRVAAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEP
                     AEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVEN
                     LNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKG
                     VQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL"
     gene            9732..10991
                     /gene="glpB"
                     /locus_tag="ACHY1N_003308"
     CDS             9732..10991
                     /gene="glpB"
                     /locus_tag="ACHY1N_003308"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HFS4045557.1"
                     /translation="MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGS
                     LDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQL
                     QGSVELAHQRVTPLGTLRATWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLR
                     ELDLSVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMI
                     LMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPG
                     DEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLD
                     VLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIA
                     QGCGGGVCAVSALHAAQQIAQRAGGQQ"
     gene            10988..12178
                     /gene="glpC"
                     /locus_tag="ACHY1N_003309"
     CDS             10988..12178
                     /gene="glpC"
                     /locus_tag="ACHY1N_003309"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit GlpC"
                     /protein_id="HFS4045558.1"
                     /translation="MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMG
                     SVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWR
                     KLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQAIGAPLFRQIEESGADLVITDCETCKWQIEMSTSLRCEHPITLLA
                     QALA"
     gene            12372..13274
                     /gene="rpnE"
                     /locus_tag="ACHY1N_003310"
     CDS             12372..13274
                     /gene="rpnE"
                     /locus_tag="ACHY1N_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HFS4045559.1"
                     /translation="MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQT
                     LRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAA
                     MQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDIT
                     IVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQ
                     CGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLE
                     QGIDRDQVLAATQLSEADLAANNH"
     gene            complement(13315..13776)
                     /locus_tag="ACHY1N_003311"
                     /pseudo
     CDS             complement(13315..13776)
                     /locus_tag="ACHY1N_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416748.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase/citrate lyase family protein"
     gene            complement(13840..15042)
                     /gene="yfaY"
                     /locus_tag="ACHY1N_003312"
     CDS             complement(13840..15042)
                     /gene="yfaY"
                     /locus_tag="ACHY1N_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HFS4045560.1"
                     /translation="MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVG
                     DNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGMVLHEAWLKEMER
                     YFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVM
                     VEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPII
                     ELKLTGPASEQQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQF
                     TGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGFENEH
                     LNFALATPDGTFALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEV
                     IESMTLSV"
     gene            complement(15142..15684)
                     /gene="yfaZ"
                     /locus_tag="ACHY1N_003313"
     CDS             complement(15142..15684)
                     /gene="yfaZ"
                     /locus_tag="ACHY1N_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaZ family outer membrane protein"
                     /protein_id="HFS4045561.1"
                     /translation="MKKIALAGLAGMLLVSASVNAMSISGQAGKEYTNIGVGFGTEST
                     GLALSGNWTHNDDDGDVAGVGLGLNLPLGPLMATVGGKGVYTNPNYGDEGYAAAVGGG
                     LQWKIGNSFRLFGEYYYSPDSLSSGIQSYEEANAGARYTIMRPVSIEAGYRYLNLSGK
                     GGNRDNAVADGPYVGVNASF"
     gene            15963..16388
                     /gene="nudI"
                     /locus_tag="ACHY1N_003314"
     CDS             15963..16388
                     /gene="nudI"
                     /locus_tag="ACHY1N_003314"
                     /EC_number="3.6.1.12"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HFS4045562.1"
                     /translation="MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVESGE
                     RIEEALRREIREELGEQLLLTEIMPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSAN
                     REVKINEEFQDYAWVKPEDLVHYDLNVAARKTLRLKGLL"
     gene            complement(16427..17029)
                     /gene="ais"
                     /locus_tag="ACHY1N_003315"
     CDS             complement(16427..17029)
                     /gene="ais"
                     /locus_tag="ACHY1N_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II)-phosphate
                     phosphatase Ais"
                     /protein_id="HFS4045563.1"
                     /translation="MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNK
                     TLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFD
                     LYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNH
                     CLTYIAKNKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNY"
     gene            17337..18476
                     /gene="arnB"
                     /locus_tag="ACHY1N_003316"
     CDS             17337..18476
                     /gene="arnB"
                     /locus_tag="ACHY1N_003316"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HFS4045564.1"
                     /translation="MSEFLPFSRPAMGVEELAAVKEVLESGWLTTGPKNQALEQAFCQ
                     LTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDV
                     DRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
                     TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDR
                     QTWGRAPQAEVLTPGYKYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPF
                     QPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYR
                     ERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ"
     gene            18480..19448
                     /gene="arnC"
                     /locus_tag="ACHY1N_003317"
     CDS             18480..19448
                     /gene="arnC"
                     /locus_tag="ACHY1N_003317"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HFS4045565.1"
                     /translation="MFEIHPVKKVSVVIPVYNEQESLPELIRRTTTACESLGKEYEIL
                     LIDDGSSDNSAHMLVEASQAENSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDAD
                     LQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
                     CMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHSEREFGESKYSFMRLI
                     NLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE"
     gene            19448..21430
                     /gene="arnA"
                     /locus_tag="ACHY1N_003318"
     CDS             19448..21430
                     /gene="arnA"
                     /locus_tag="ACHY1N_003318"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016742 - hydroxymethyl-, formyl- and
                     related transferase activity [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HFS4045566.1"
                     /translation="MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGS
                     VARLAAERGIPVYAPDDVNHPLWVERIAQLSPDVIFSFYYRHLICDEILQLAPAGAFN
                     LHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAIT
                     LHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLH
                     NMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEI
                     VTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLILGVNGFIGNHLTER
                     LLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGS
                     SRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIG
                     NPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIR
                     NAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS"
     gene            21427..22317
                     /gene="arnD"
                     /locus_tag="ACHY1N_003319"
     CDS             21427..22317
                     /gene="arnD"
                     /locus_tag="ACHY1N_003319"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HFS4045567.1"
                     /translation="MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDN
                     MGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHE
                     VGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIE
                     AKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLL
                     NRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVV
                     RGNIAGREGWLGCQQIAGSR"
     gene            22317..23969
                     /gene="arnT"
                     /locus_tag="ACHY1N_003320"
     CDS             22317..23969
                     /gene="arnT"
                     /locus_tag="ACHY1N_003320"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000030 - mannosyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006493 - protein O-linked glycosylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HFS4045568.1"
                     /translation="MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLA
                     SGDWIVPQLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFT
                     LRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG
                     KSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLT
                     VLPWGLAIAQREPDFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLP
                     GALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLMAHYALLA
                     AKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLW
                     AFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSR
                     YILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHR
                     QEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK"
     gene            23966..24301
                     /gene="arnE"
                     /locus_tag="ACHY1N_003321"
     CDS             23966..24301
                     /gene="arnE"
                     /locus_tag="ACHY1N_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HFS4045569.1"
                     /translation="MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLAL
                     ACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIG
                     GIVILGSTV"
     gene            24301..24687
                     /gene="arnF"
                     /locus_tag="ACHY1N_003322"
     CDS             24301..24687
                     /gene="arnF"
                     /locus_tag="ACHY1N_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416761.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HFS4045570.1"
                     /translation="MGLMWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFG
                     LDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFS
                     LKALLGVACIMSGLMLIFLPMTKQRY"
     gene            complement(24681..24947)
                     /gene="pmrD"
                     /locus_tag="ACHY1N_003323"
     CDS             complement(24681..24947)
                     /gene="pmrD"
                     /locus_tag="ACHY1N_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416762.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HFS4045571.1"
                     /translation="MEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGD
                     LLSPLQNALYCINREKLHTVKVLSASSYSPDEWERQCKVAGKTQ"
     gene            complement(25057..26412)
                     /gene="menE"
                     /locus_tag="ACHY1N_003324"
     CDS             complement(25057..26412)
                     /gene="menE"
                     /locus_tag="ACHY1N_003324"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008756 - o-succinylbenzoate-CoA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HFS4045572.1"
                     /translation="MIFSDWPWRHWRQVRGEAIALRLNDEQLNWRELCARVDELASGF
                     AAQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQF
                     ALVPDGENTFPALTSLHIQRVEGAHAATWQPTRLCSMTLTSGSTGLPKAAVHTYQAHL
                     ASAEGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFAS
                     TVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYAT
                     RDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGH
                     RPVAVMEYDHESVDLSEWVKDKLASFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQ
                     Q"
     gene            complement(26409..27371)
                     /gene="menC"
                     /locus_tag="ACHY1N_003325"
     CDS             complement(26409..27371)
                     /gene="menC"
                     /locus_tag="ACHY1N_003325"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HFS4045573.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGE
                     ISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAA
                     NYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
                     DANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLRE
                     PDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLAR
                     IAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL"
     gene            complement(27371..28228)
                     /gene="menB"
                     /locus_tag="ACHY1N_003326"
     CDS             complement(27371..28228)
                     /gene="menB"
                     /locus_tag="ACHY1N_003326"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008935 - 1,4-dihydroxy-2-naphthoyl-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HFS4045574.1"
                     /translation="MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(28243..29001)
                     /gene="menH"
                     /locus_tag="ACHY1N_003327"
     CDS             complement(28243..29001)
                     /gene="menH"
                     /locus_tag="ACHY1N_003327"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070205 -
                     2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HFS4045575.1"
                     /translation="MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLY
                     VDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAG
                     LCGVIVEGGHPGLQNAEQRAERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDDQ
                     RRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAA
                     ELAADCHVIPRAGHNAHRENPAGVIASLAQILRF"
     gene            complement(28998..30668)
                     /gene="menD"
                     /locus_tag="ACHY1N_003328"
     CDS             complement(28998..30668)
                     /gene="menD"
                     /locus_tag="ACHY1N_003328"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070204 -
                     2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylic-acid synthase activity [Evidence IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HFS4045576.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAEN
                     SAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTRDIPARWLVSTIDHALGTLH
                     AGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSEL
                     QQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWL
                     ELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
                     ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKY
                     HRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL"
     gene            complement(30757..32052)
                     /gene="menF"
                     /locus_tag="ACHY1N_003329"
     CDS             complement(30757..32052)
                     /gene="menF"
                     /locus_tag="ACHY1N_003329"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416768.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008909 - isochorismate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HFS4045577.1"
                     /translation="MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWL
                     ASQQTYPQFYWQQRNGDEEAAVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDP
                     SQGNLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIQAREFIATLVSIKPLPGLHLTT
                     TREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLN
                     LNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWLM
                     ADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVI
                     CLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKIS
                     GNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME"
     gene            complement(32131..32436)
                     /gene="elaB"
                     /locus_tag="ACHY1N_003330"
     CDS             complement(32131..32436)
                     /gene="elaB"
                     /locus_tag="ACHY1N_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HFS4045578.1"
                     /translation="MSNQFGDTRIDDDLTLLSETLEEVLRSSGDPADQKYVELKARAE
                     KALDDVKKRVSQASDSYYYRAKQAVYRADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(32491..32952)
                     /gene="elaA"
                     /locus_tag="ACHY1N_003331"
     CDS             complement(32491..32952)
                     /gene="elaA"
                     /locus_tag="ACHY1N_003331"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4045579.1"
                     /translation="MIEWQDLHHSELSVSQLYALLQLRCAVFVVEQNCPYQDIDGDDL
                     TGDNRHILGWKNDELVAYARILKSDDDLEPVVIGRVIVSEALRGEKVGQQLMSKTLDT
                     CTHHWPDKPVYLGAQAHLQNFYQSFGFIPVTEVYEEDGIPHIGMAREVIQA"
     gene            33017..33934
                     /gene="rbn"
                     /locus_tag="ACHY1N_003332"
     CDS             33017..33934
                     /gene="rbn"
                     /locus_tag="ACHY1N_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416771.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HFS4045580.1"
                     /translation="MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQ
                     HQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPQGIREFVE
                     TALRISGSWTDYPLEIVEIGAGEILDDGLRKVTAYPLEHPLECYGYRIEEHDKPGALN
                     AQALKAAGVPPGPLFQELKAGKTITLEDGRQINGADYLAAPVPGKALAIFGDTGPCDA
                     ALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYD
                     DKGCQHLLRECRSIFPATELANDFTVFNV"
     gene            34122..35246
                     /gene="elaD"
                     /locus_tag="ACHY1N_003333"
                     /pseudo
     CDS             34122..35246
                     /gene="elaD"
                     /locus_tag="ACHY1N_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416772.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ElaD/SseL family deubiquitinase"
BASE COUNT         8662 a         9406 c         8708 g         8470 t
ORIGIN      
        1 catcaacaat cgcttacatt cgtttatata ttgaccacaa ctgatacatc agattatgtg
       61 atgactcgtg cttagatcaa tttttgcaat cattagcaaa aagattaata aaccatctat
      121 atcaatttat ccaacctatt ctgccgttca agaaatcgcc gaacagttat ttttaacaaa
      181 tttttctctt cccattgact ttcccggaca ccttgtctga cctaaggtgc gcgaaagcca
      241 ctttttcctt cctgagttat ccacaaagtt atgcacttgc aagagggcca ttttcacact
      301 atcttgcagt gaatcccaaa cataccccct atatatagtg ttctaagcag cttcccttac
      361 tacaggtagt ctgcatgaaa ctattgcgga aagaattcca aaaacaggta cgacatacat
      421 gaatcagaat ctgctggtga caaagcgcga cggtagcaca gagcgcatca atctcgacaa
      481 aatccatcgc gttctggatt gggcggcaga aggactgcat aacgtttcga tttcccaggt
      541 cgagctgcgc tcccacattc agttttatga cggtatcaag acctctgaca tccacgaaac
      601 cattatcaag gcggccgcag acctgatctc ccgtgatgcg ccggattatc agtatctcgc
      661 cgcgcgcctg gcgatcttcc acctgcgtaa aaaagcctac ggccagtttg agccgcctgc
      721 gctgtacgac cacgtggtga aaatggtcga gatgggcaaa tacgataatc atctgctgga
      781 agactacacg gaagaagagt tcaagcagat ggacacgttt atcgatcacg accgtgatat
      841 gaccttctct tatgctgccg ttaagcagct ggaaggcaaa tatctggtac agaaccgcgt
      901 gaccggcgaa atctacgaaa gcgcccagtt cctttatatt ctggttgccg cgtgcctgtt
      961 ctcgaactac ccgcgtgaaa cgcgcctgca atatgtgaag cgtttttacg acgcggtttc
     1021 cacatttaaa atttcgctgc cgacgccaat catgtccggc gtgcgtaccc cgactcgtca
     1081 gttcagctcc tgcgtactga tcgagtgcgg tgacagtctg gattccatca acgctacctc
     1141 cagcgcgatt gtgaaatacg tttcccagcg tgccgggatc ggcatcaacg ccgggcgtat
     1201 tcgtgcgctg ggtagcccga ttcgcggtgg tgaagcgttc cataccggct gtattccgtt
     1261 ctacaaacat ttccagacag cggtgaaatc ctgctctcag ggcggcgtgc gcggcggtgc
     1321 ggcaacgctg ttctacccga tgtggcatct ggaagtggaa agcctgctgg tgttgaaaaa
     1381 caaccgtggt gtggaaggca accgcgtgcg ccatatggac tacggggtac agatcaacaa
     1441 actgatgtat acccgcctgc tgaaaggtga agatatcacc ctgttcagcc cgtccgacgt
     1501 accggggctg tacgacgcat tcttcgccga tcaggaagag tttgaacgcc tgtataccaa
     1561 atatgagaaa gacgacagca tccgcaagca gcgtgtgaaa gccgttgagc tgttctcgct
     1621 gatgatgcag gaacgtgcgt ctaccggtcg tatctatatt cagaacgttg accactgcaa
     1681 tacccatagc ccgtttgatc cggccatcgc gccagtgcgt cagtctaacc tgtgcctgga
     1741 gatagccctg ccgaccaaac cgctgaacga cgtcaacgac gagaacggtg aaatcgcgct
     1801 gtgtacgctg tctgctttca acctgggcgc aattaatagc ctggatgaac tggaagagct
     1861 ggcaattctg gcggttcgtg cacttgacgc gctgctggat tatcaggatt acccgatccc
     1921 ggccgccaaa cgtggagcga tgggtcgtcg tacgctgggt attggtgtga tcaacttcgc
     1981 ttactacctg gcgaagcacg gtgtgcgtta ctccgacggc agcgccaaca acctgacgca
     2041 taaaaccttc gaagcgattc agtattacct gctgaaagcg tctaacgagc tggcaaaaga
     2101 gcaaggcgcg tgcccgtggt ttaacgaaac cacttacgcg aaagggatcc tgccgatcga
     2161 tacctataag aaagatctgg ataccatcgc taatgagccg ctgcattacg actgggaagc
     2221 attgcgtgaa tcaatcaaaa cgcacggcct gcgtaactcc acgctttctg ccctgatgcc
     2281 gtcagagact tcttcacaga tctctaacgc cactaacggt attgaaccgc cgcgcggtta
     2341 cgtcagcatc aaagcgtcga aagacggtat tttgcgccag gtggtgccgg actacgagca
     2401 cctgcacgac gcctatgagc tgctgtggga aatgccgggt aacgatggct acctgcaact
     2461 ggtaggtatc atgcagaaat ttatcgatca gtcgatctct gctaacacca actacgatcc
     2521 gtcacgtttc ccgtcaggaa aagtgccgat gcagcagttg ctgaaagacc tgctcaccgc
     2581 ctacaaattc ggggtcaaaa cgctgtatta tcagaacacc cgtgacggcg ctgaagacgc
     2641 gcaggacgat ctggtaccgt caatccagga cgatggctgc gaaagcggcg catgtaagat
     2701 ctgatattga gatgccggat gcagcgtgaa cgccttatcc ggcctacggc tcggatttgt
     2761 aggcctgata agacgcgtca gcgtcgcatc aggcacagga tgcggcgtaa aatgccttat
     2821 ccggcattaa actcccaaca ggacacactc atggcatata ccaccttttc acagacgaaa
     2881 aatgatcagc tcaaagaacc gatgttcttt ggtcagccgg tcaacgtggc tcgctacgat
     2941 cagcaaaaat atgacatctt cgaaaagctg atcgaaaagc agctctcttt cttctggcgt
     3001 ccggaagaag ttgacgtttc tcgcgaccgt atcgattacc aggcactgcc tgaacacgaa
     3061 aaacacatct ttatcagcaa cctgaaatat cagacgctgc tggattccat tcagggccgt
     3121 agcccgaacg tggcactgct gccgctgatc tcgatcccgg aactggagac ctgggtcgaa
     3181 acctgggcgt tctcagaaac gattcattcc cgttcctata ctcatatcat tcgtaatatc
     3241 gttaacgatc cgtctgttgt gtttgacgat atcgtcacca acgagcagat ccagaaacgt
     3301 gcggaaggga tctccagcta ttacgatgag ctgatcgaaa tgaccagcta ctggcatctg
     3361 ctgggcgaag gtacccacac cgttaacggt aaaactgtga ccgttagcct gcgcgagctg
     3421 aagaaaaaac tgtatctctg cctgatgagc gttaacgcgc tggaagcgat tcgtttctac
     3481 gtcagctttg cttgttcctt cgcatttgca gaacgcgaat tgatggaagg caacgccaaa
     3541 attattcgcc tgattgcccg cgacgaagcc ctgcacctga ccggcaccca gcatatgctg
     3601 aatctgctgc gcagcggcgc ggacgatcct gagatggcgg aaattgccga agagtgtaag
     3661 caggagtgct atgacctgtt tgttcaggca gctcaacagg agaaagactg ggcggattat
     3721 ctgttccgcg acggttcgat gattggtctg aataaagaca ttctctgcca gtacgttgaa
     3781 tacatcacca atatccgtat gcaggcagtc ggtttggatc tgccgttcca gacgcgctcc
     3841 aacccgatcc catggatcaa cacctggctg gtgtctgata acgtgcaggt tgctccgcag
     3901 gaagtggaag tcagttctta tctggtcggg cagattgacg cggaagtgga caccgacgat
     3961 ttgagtaact tccaactctg atggcccgcg ttaccctgcg catcactggc acacaactgc
     4021 tgtgccagga tgaacaccct tcccttctgg cggcgctgga atcccacaat gtggcggttg
     4081 agtatcagtg tcgcgaaggt tactgcggct cctgtcgcac ccgtctggtt gcaggtcagg
     4141 ttgactggat tgccgaaccg ttagccttta ttcagccggg ggaaattttg ccctgttgtt
     4201 gccgggcaaa aggcgatatt gaaatcgaga tgtgaattgg ttgtagtgcc agatacaacg
     4261 cttatgcgtc ttatctggcc tacaacgatt acatggcgta gtaatacgct ttcacctgct
     4321 cccagtccgc tttggggatt ggctccagat atttttccag ctggcggaag tcatgattaa
     4381 tcgctttatc gcgacgcaag cggcgacgac ttttctccag gtcaagaaaa ccagcttctg
     4441 cattaccttc tgttttcaca tagatatggc gaacataaca acagccatgc tgacgattaa
     4501 tgctatgcat tttcttaaac gccagcgcca ctgctttcaa catggcttgc cgtacttcgt
     4561 cagaataagg cgatactgca tgctgggcat accagtcagc aatgctgatg aaccccgcca
     4621 tatcttcagt caccagcaac gctcgccatt caccctcaat tttcaccgct tcaccaaaaa
     4681 cgatcttcgg cacgatgaca ccggcccgtt ccagttcttt aattaccgca acctcacgga
     4741 caatcgttgg tcggccgaac ggataacgta cggaatgaaa cagatgatgc gtcatgcgct
     4801 ttacatacag ctttttgccg ttgcgctcga cgcattgcac cccgctcata ccattacggc
     4861 gatagttagg ctcttcaacc cagtcgccct ctgttgccca ccagtgatta aattcgtcgt
     4921 actttgctga aactgccata ccctatcgcc tgtcattttt attaacgaca atgactatag
     4981 gtggttacct gaggaaaatc ttaatgaaac gtgtcgtatt aatgaatttc ttttgccact
     5041 actagcgtga caccgctttt acccttcatt tgcagcgcat agattccacc agccactacc
     5101 actaatagtg cgcccagtag ataaaatgtg aatttaatca gtcggataca gcgatgaagt
     5161 ttattcgaca gggattaggc atcgccttac aaccagagtt aacgctgaaa agcattgcag
     5221 gtgaattgtg ttccgttcct cacgaaccaa ccttctatcg acagatttcg ttgttggcta
     5281 aagaaaagcc ggtagaaggc agtccactgt ttttactaca aacgtgtacg gaacaactcg
     5341 tggtgaatgg aaaaatttga tgtgagacag gatggcgcat gaacgccatc ctgcagtagc
     5401 attactcttt attaaggaat tttactgcct tatcagggaa atcagtaaac agcccattta
     5461 cacccgcttt gttatacaga gcatcatata actgattcac atcagtagtg tattcaggca
     5521 gtttatctga ccgcacggta taaggatgca ctaccagttt attctgctga gcatcttgca
     5581 ccatgccagt gagtttgata ttacccggct gcgatgtttc ctcaatcaac atatggtaat
     5641 ccggcccgat accgtcggca tattccgcca cctgtttcat agcacccggc ttaaacatcc
     5701 agtcgtagtt gtaattaacc cagcttccat ccggctgttt ctgctgcgtt tcattccagt
     5761 cggtataggc aatcagctgt accagattga gatccatgcc cattttgggt tccagctcat
     5821 tcttaatacg cttcagctca tcagcatcaa aacattgcaa ataaactttg tcgtccttac
     5881 cggtgtaacc atatttcttc agcacttcca gcgtttttgc cgcaatatcc ttcccttcct
     5941 gatgatggaa ccacggcgct ttaatttctg gatagatacc gatatttttc ccggtagagt
     6001 gatttaaccc ctgaacaaat tcaatctctt cttcaaaggt gtgcacccgg aagtcggact
     6061 tacccattgg gaaacgcccc ggataagtct gtactttttt accgttttca atatcgaaac
     6121 cttcggtaaa tttcagcgac ttaatttcat ccagcgtgaa atctatcgcg tagtaacgac
     6181 cgtctttgcg cgcccgatcc gggaaacgat cggcaacatc agtaacacga tcgagataat
     6241 ggtcatgcag aacaaccaga tggtcgtctt tggtcatcac caaatcctgt tccagataat
     6301 ccgctccctg cgcatacgcc atcgcttttg ctggcagcgt atgctccggc aaatatccac
     6361 tggcaccgcg atgggcgatg actatttttt cgttgctgtc cgccgccatt gcactgcttc
     6421 ccatgactat agtgctcatc atgatcgcca tgctaaggtt tttcagcttc aatttcatgc
     6481 cattagcctc cgttgcgttt ttgcagtaat tgttcatggc gacgtttttc gccaatcatc
     6541 acaacaatca acaagataac cgccagaatg ctgccgccaa tcattaccat aaagccgcca
     6601 tcccagccga agaagtccac ggtgtagcca acaatcgcgc tcgccgccac cgaaccgccc
     6661 aggtaaccaa acagcccggt aaagcccgct gccgtacctg ccgctttttt cggtgccagt
     6721 tccagcgcat gcagaccgat cagcatcaca ggaccgtaga tcaggaagcc gataacaatc
     6781 atacaaatca tatcgacggt tgggttacct gccgggttca tccagtaaac gatagtcgcg
     6841 atggtcacca gtgtcataaa gaaaacgccg gttgccccac ggttgccacg gaagacttta
     6901 tccgacatcc agccgcacag cagggtgccc ggaatacccg catactcata gaagaagtag
     6961 gcccaggaag atttatccag cgcgaaatgt ttaacctctt tcaggtaagt cggtgaccag
     7021 tcgaggatgc cgtaacgcag cagataaacg aacacgttgg cgatggcgat ataccacagc
     7081 aatttgttcg gcaacacgta ctgcatgaag atctgcttcg ccgtcagttc ctgttccgct
     7141 ttttcgttat agtcgtccgg gtaatcattt ttgtactctt cgatcggcgg caaaccacaa
     7201 gattgcgggg tatcgcgcat catcgcaaag gcgaataatg ccaccagaat ggcgcagaaa
     7261 gcgggcatat agagcgccgc atgccagtca ttgaaccagg ccatccccag caggaacagc
     7321 agcggcggaa taccaccacc gacgttgtgc gcacagttcc acactgacac aatgccgcca
     7381 cgttctttct gcgaccacca gtgcaccata gtacgaccac acggcggcca ccccatcccc
     7441 tggaaccaac cgcagaggaa caacagtaca aacatcaccg caatgctcga cgtcgcccat
     7501 ggcacaaagc ccataaacaa catcactgcc gccgccagaa tcaaacctgc gggcaggaaa
     7561 acgcgcggat tcgagcgatc cgataccgaa cccatgatga atttcgaaaa tccataagca
     7621 atcgagatcc ccgaaagggc aaaacctaaa tcaccgcgtg agaatccctg ctcaaccaga
     7681 taaggcatag caagcgcaaa gttcttacga accaaatagt aagccgcata gccaaagaat
     7741 atccccagga aaatttgcca gcgcaatcga cgataagtcg gatcgatctc cgcggcaggt
     7801 aagcgcgctt tgtgtggcgc tggtttaaaa atactcaaca ttgatagcct ccgtggcccg
     7861 tggtcttatt tatgattaac agcctgattc agtgagagaa cctgccgttt cttgagttgc
     7921 cgcgatgtta agaaaacatt cataaattaa atgtgaattg ccgcacacat tattaaataa
     7981 gatttacaaa atgttcaaaa tgacgcatga aatcacgttt cactttcgaa ttatgagcga
     8041 atatgcgcga aatcaaacaa ttcatgtttt tactatggct aaatggtaaa aaacgaactt
     8101 cagagggata acaatgaaaa ctcgcgactc gcaatcaagt gacgtgatta tcattggcgg
     8161 cggcgcaacg ggagccggga ttgcccgcga ctgtgccctg cgcgggctgc gcgtgatttt
     8221 ggttgagcgc cacgacatcg caaccggtgc caccgggcgt aaccacggcc tgctgcacag
     8281 cggtgcgcgc tatgcggtaa ccgatgcgga atcggcccgc gaatgcatta gtgaaaacca
     8341 gatcctgaaa cgcattgcac gtcactgcgt tgaaccaacc aacggcctgt ttatcaccct
     8401 gccggaagat gacctctcat tccaggccac ttttattcgc gcctgcgaag aagcagggat
     8461 cagcgcagaa gctatagacc cgcagcaagc gcgcattatc gaacctgccg ttaacccggc
     8521 actgattggc gcggtgaaag ttccggatgg caccgttgat ccatttcgtc tgaccgcagc
     8581 aaacatgctg gatgccaaag aacacggtgc cgttatcctt accgctcatg aagtcacggg
     8641 gctgattcgt gaaggcgcga cggtgtgcgg tgttcgtgta cgtaaccatc tcaccggcga
     8701 aactcaggcc cttcatgcac ctgtcgtggt taatgccgct gggatctggg ggcaacacat
     8761 tgccgaatat gccgatctgc gcattcgcat gttcccggcg aaaggatcgc tgctgatcat
     8821 ggatcaccgc attaaccagc atgtgatcaa ccgctgccgt aaaccttccg acgccgatat
     8881 tctggtgcct ggcgatacca tttcgctgat tggcaccacc tctttacgta ttgattacaa
     8941 cgagattgac gataatcgag tggcggcaga agaggttgat attctgctgc gtgaagggga
     9001 aaaactggcc cccgtgatgg cgaaaacgcg cattttgcgg gcctattctg gcgtgcgccc
     9061 gctggttgcc agcgatgacg acccgagcgg acgtaacgtc agccgtggca tcgtgctgct
     9121 cgaccatgct gaacgcgatg gtctggacgg atttatcacc atcaccggtg gcaaactgat
     9181 gacctatcgg ctgatggctg aatgggctac cgacgcggta tgccgcaaac tgggcaacac
     9241 gcgcccctgt acgactgccg atctggcact gcctggttca caagaacccg ctgaagttac
     9301 cttgcgtaaa gtcatctccc tgcctgcccc gctgcgcggt tctgcggttt atcgtcatgg
     9361 cgatcgcacg cctgcctggc tgagcgaagg ccgtctgcat cgtagcctgg tatgtgagtg
     9421 cgaagcggta actgcgggtg aagttcagta cgcggtagaa aatttaaacg ttaatagcct
     9481 gctggattta cgccgtcgta cccgtgtggg gatgggtacc tgccagggcg aactctgcgc
     9541 ctgccgcgct gccggactgc tgcaacgttt taacgtcacg acgtccgcgc aatctatcga
     9601 gcaactttcc accttcctta acgaacgctg gaaaggcgtg caacccatcg cctggggaga
     9661 cgcactgcgc gaaagcgaat ttacccgctg ggtttatcag ggactgtgtg gtctggagaa
     9721 ggagcagaaa gatgcgcttt gatactgtca ttatgggcgg cggcctcgcc ggattactct
     9781 gtggcctgca actgcaaaaa cacggcctgc gctgtgccat tgtcacgcgt ggtcaaagcg
     9841 cgctgcattt ctcatccggt tcgctggatt tgctgagcca tctgcctgat ggtcaaccgg
     9901 tgacagacat tcacagtgga ctggaatctt tgcgtcagca ggcaccagcc catccttaca
     9961 gtcttctcga accacaacgc gtgctcgatc tcgcttgcca ggcgcaggca ttgatcgctg
    10021 aaagcggtgc gcaattgcag ggcagcgtgg aactggccca tcagcgcgtt accccgctcg
    10081 gcactttgcg tgcaacctgg ttaagttcgc cagaagttcc cgtctggccg ctacccgcga
    10141 agaagatatg tgtagtgggg ataagcgggc tgatggattt ccaggcgcat cttgcggcgg
    10201 cttcgttgcg cgaactggat ctttcggttg aaaccgcaga aatagagctg ccggaactgg
    10261 atgtcctgcg caataacgcc accgaatttc gcgctgtgaa tatcgcccgt ttccttgata
    10321 atgaagaaaa ctggccgctg ttacttgatg cgcttattcc tgtcgccaat acctgcgaaa
    10381 tgatcctgat gcccgcctgc ttcggcctgg ccgatgacaa actgtggcgt tggttgaatg
    10441 aaaaactacc ttgttcactg atgcttttgc caacgctgcc gccttccgtg ctgggcattc
    10501 gtctgcaaaa ccagttacag cgccagtttg tgcgccaggg tggcgtgtgg atgccgggcg
    10561 atgaagtgaa aaaagtgacc tgtaaaaatg gcgtagtgaa tgaaatctgg acccgcaatc
    10621 acgccgatat tccgctacgt ccacgtttcg cggttctcgc cagcggcagt ttctttagtg
    10681 gcggactggt agcggaacgt aacggcattc gcgagccgat tctcggcctt gatgtgctac
    10741 aaaccgccac gcggggtgaa tggtataagg gcgatttttt tgcgccgcaa ccgtggcagc
    10801 agttcggtgt aaccactgat gagacgctac gcccgtcgca ggcagggcaa accattgaga
    10861 acctgtttgc catcggttcg gtgctgggcg gatttgatcc catcgcccag ggatgcggcg
    10921 gcggtgtttg tgccgtcagt gctttacatg ccgctcaaca gattgcccaa cgcgcaggag
    10981 gccaacaatg aacgacacca gcttcgaaaa ctgcattaag tgcaccgtct gcaccaccgc
    11041 ctgcccggtg agccgggtga atcccggtta tccagggcca aaacaagccg ggccggatgg
    11101 cgagcgtctg cgtttgaaag atggcgcact gtatgacgag gcgctgaaat attgcatcaa
    11161 ctgcaaacgt tgtgaagtcg cctgcccgtc cgatgtgaag attggcgata ttatccagcg
    11221 cgcgcgggca aaatatgaca ccacgcgccc gtcgctgcgt aattttgtgt tgagtcatac
    11281 cgacctgatg ggtagcgttt ccacgccgtt cgcaccaatc gtcaacaccg ctacctcgct
    11341 gaaaccggtg cggcagctgc ttgatgcggc gttaaaaatc gatcatcgcc gcacgctacc
    11401 gaaatactcc ttcggcacgt tccgtcgctg gtatcgcagc atagcggctc agcaagcaca
    11461 atataaagac caggtcgctt tctttcacgg ctgcttcgtt aactacaacc atccgcagtt
    11521 aggtaaagat ttaattaaag tgctcaacgc aatgggtacc ggtgtacaac tgctcagcaa
    11581 agaaaaatgc tgcggcgtac cgctaatcgc caacggcttt accgataaag cacgcaaaca
    11641 ggcaattacg aatgtagagt cgatccgcga agctgtggga gtaaaaggaa ttccggtgat
    11701 tgccacctcc tcaacctgta catttgccct gcgcgacgaa tacccggaag tgctgaatgt
    11761 cgacaacaaa ggcttgcgcg atcatatcga actggcaacc cgctggctgt ggcgcaagct
    11821 ggacgaaggc aaaacgttac cgctgaaacc gctgccgctg aaagtggttt atcacactcc
    11881 gtgccatatg gaaaaaatgg gctggacgct ctacaccctg gagctgttgc gtaaaatccc
    11941 ggggcttgag ttaacggtgc tggattccca gtgctgcggt attgcgggta cttacggttt
    12001 caaaaaagag aactacccca cctcacaagc catcggtgcg ccactgttcc gccagataga
    12061 agagagcggc gcggatctgg tcatcaccga ctgcgaaacc tgcaaatggc agattgagat
    12121 gtccacgagc cttcgctgcg aacatccgat tacgctactg gcccaggcgc tggcttaacc
    12181 gaccttttga tgcccggtaa gcacattgct tatcgggcat ttttgcgagc gcgattccac
    12241 gcaccatgta tgcgttgcaa cgctttgaaa attcctctga aaatgtctcg caaaggctga
    12301 aactgacaga tgtcaaaggc ccgggataga cgtaatgtcg cgtcatcata aatatcaggt
    12361 gacggacaac catgaccgaa tcaacaacat cctccccgca tgatgcggtg tttaaaacct
    12421 ttatgttcac acccgaaacc gcacgggatt ttctcgaaat acatttacca gaaccactgc
    12481 gcaagctttg caacctgcaa accttacgcc tggaacccac tagttttatt gaaaaaagtt
    12541 tacgcgctta ctactcggat gttttgtggt ccgtggaaac cagcgacggt gacggctata
    12601 tctactgcgt gattgaacat caaagctctg cagaaaagaa tatggctttt cggctaatgc
    12661 gctatgccac tgccgccatg cagcgtcacc tggataaagg ctatgacaga gttccgctgg
    12721 tggtgccatt gctgttttat catggcgaaa catcgcccta cccgtactca cttaactggc
    12781 tggatgagtt tgacgatccg caacttgccc ggcagttgta caccgaagct tttccgttgg
    12841 tggatatcac catcgtacct gacgatgaga tcatgcaaca tcggcgtata gctctgctgg
    12901 aactgattca aaagcatatt cgcgaccgcg atttaatcgg catggtcgac aggatcacca
    12961 cgcttttggt tagaggcttc actaatgaca gccagctaca aacactgttt aattatctgc
    13021 tgcaatgcgg cgatacctcc cgtttcaccc gttttattga ggagattgcc gaacgttcac
    13081 cactacaaaa ggagagatta atgactattg ctgaacggct acggcaggaa gggcatcaaa
    13141 ttggctggca ggaaggtatg catgaacaag ccattaaaat tgctttgcgc atgctggaac
    13201 agggcattga tcgtgaccag gtgctcgcgg ccacccagct aagcgaagcc gatctggcag
    13261 cgaataacca ctaattaaca caggcccaca gccgatcccc atgggccttt gatatcaata
    13321 actacctttt atgcgtggcc catttttgcc tgatttaaac atcgccagtc gttgatccag
    13381 ggcatcgctg tagagcatcg tgtcaacgcc aacagcgaca aagttcgctc cccacgccag
    13441 gcattgctgc gccatatcag gagccacagc cagaaaacca gccgctttac ccgcagcacg
    13501 gatccgccga atactggttt caataattcg ctgcacttcc gggtgccctg cgttatccgg
    13561 gtagcccaac gacgcagaaa gatccgcagg tccaataaac acgccatcaa tcccttcgac
    13621 gtcgaggatt tcgtccaggt tatccagtgc cgttttactt tccacctgca ccaacagaca
    13681 aagtgaatcg ttaacttgcg ccatgtaatt ctcaatgcgt ccccagcgcg cagcccgtgc
    13741 cacactggcc ccaacaccac gctcaccgta gggagggttg gacaagtttt gccggagggg
    13801 gaatgtgccg gtgcagtaaa ccggcacaga gtggcggaat cagacagata aggtcatgga
    13861 ctcaataacc tcaatccagc catgctcact ggcgatatcc tggccgttta accaacggcg
    13921 cagcatattc agtgccatca ttgcgcacac ttcctgacgg atagccaggc tgtagcgtgt
    13981 agtgctgaaa cgcacacgca gagcgaaagt gccgtctggc gtggctagcg caaagttgag
    14041 atgctcgttc tcgaaacccg aaacagccag tgccagcccg gcaaaatggt tggcccgccg
    14101 ttctgtaatc cagtgcgcag tttgcgccag ggtttcttcc tgtgaaggaa ccacttcaca
    14161 cgccagcaat ggagcacctg cgcgagaaag ttgcaaagcc aataaaccgc cggtgaattg
    14221 ctcgctcaac gtcaggctga actggcggtt ttgcaattcg cgactgatct gcgcgggcag
    14281 tccttcggtg ccttcgaaaa tcacgctctg tccggcaaca cgtttaacgt ccagccacag
    14341 tttttccatc gcctgttgct cgcttgccgg tccggtgagt ttcagttcga taatcggcat
    14401 tgaagagcga tagcccattg ttacgcccgg cggcagttgt agagtgtcca ggctttgtgc
    14461 cagatcgctt tccgaacgac caaaggtagt taaacgcaga caaaccggcg gctgtggtaa
    14521 agaaaaacgc tcgcgcagac gcggcaggat ttcgtgctcg accatcacct taaattctga
    14581 cggtacgccg ggagtaaaga acatcaggca acgattaagc tgcacggcaa aaccacaggc
    14641 ggtgcctacc gggttattga taaattcagc actggcaggc agctccgctt gtttacggtt
    14701 gctcggtgcc attactcgtc cacgttcgtg gaaatagcgt tccatctctt tgagccaggc
    14761 ttcatgcagc accatgcctt caccttttgc tgtcgcagcg gcgagtgcgc ttaaatcatc
    14821 gctggtcggt cccagcccgc cgttaacgat cagcacatcg gcgtgctgac tacgttcgcg
    14881 aagaatggtg actaagtcat caaggttatc ccccaccgta ttgcggcgag ataatggcag
    14941 cccctgatga aagaaaaaat cggccagcca ggcagcgtta gtgtcaacga tttgcccgtg
    15001 taacacttca tccccggtgg atagcatttc cacttttaac atggttatct cctgcttttg
    15061 ttatcgaatc actataacgc aaagggagat aaggcgtagt aagaaactga atggcgcgac
    15121 agaatgccgc gccggaaggg atcagaaact ggcgttaacc ccaacatacg ggccgtcagc
    15181 cacggcgttg tcgcggttac cgcctttacc cgacagattc aggtagcgat aacccgcctc
    15241 aatactgact ggacgcataa tggtgtaacg cgcgccagca ttcgcttcct cataactttg
    15301 aataccgctg gagagcgaat ccggagagta gtaatactcg ccaaacaaac ggaagctgtt
    15361 gccaattttc cactgcaaac cacctcctac cgctgcggca taaccttcat cgccgtaatt
    15421 cgggttggtg taaacgcctt ttccgccaac ggtcgccatt aacggcccga gaggcagatt
    15481 caaccccagc cccacgcccg cgacgtcacc gtcgtcgtcg ttatgtgtcc agttaccgct
    15541 taaagccagg cccgtcgatt cagtcccaaa accgacacca atattggtgt attctttacc
    15601 cgcctggccg ctgatgctca ttgcattgac cgatgcagaa accaacagca ttccggccag
    15661 acctgctagc gcaatttttt tcattatccc ctttcccaca agcaattaat caaaattccc
    15721 aaagctgcgg gattgtactg cctggcacag aggattcaat gagcgaaaaa agggatctag
    15781 tcacttattg taactaaata cttcttaaat aattaaacgc cgaaaaaata aacacacttt
    15841 accgatacac acaaaaataa taataagtgc agttatcatt gcaaaagaga ttactgtcac
    15901 tttcacatat ttctgagtta ccgtattctc atggtttctt tttatttata aggaataccc
    15961 ctatgcgaca acggactatt gtatgccctt tgattcaaaa tgatggtgct tatttgctgt
    16021 gtaaaatggc cgacgatcgc ggcgttttcc ccggtcaatg ggcgctttcg ggtggcggcg
    16081 tggagtctgg cgaacgaatt gaagaggcac tacgccgcga aattcgcgaa gaactgggag
    16141 aacagctgct tttgacagaa atcatgccgt ggaccttcag cgatgatatt cgcaccaaga
    16201 cgtatgcaga tggtcgcaag gaagagattt atatgattta cctgattttt gactgcgttt
    16261 ctgccaaccg agaagtgaaa ataaacgaag agtttcagga ctacgcgtgg gtaaaacctg
    16321 aagatctggt gcattatgat ttaaatgttg ccgcccgaaa aacgttacgt ttgaaaggtc
    16381 ttctttaaca atgatgacag ccatcactgg ctgtcagatt gaaaatttag tagttaacga
    16441 attccccatc cagataaact ttgccttttt ccacatgcat gactaaacca tccagataat
    16501 caggtttaaa tgtcgcatca cgcttatttt tagcaatata tgtcaggcaa tgattatggg
    16561 tgaaaataac gatattttta tcaggcgctt tgctttgtaa gtccttaatt gcactataaa
    16621 tctcattacc gcactgaaga agtcgtttat ctaccgtcag ctttttaccc gcggaaaacc
    16681 aggtcgccga ctgaatggtc cggacggtat tactggaata aagatcgaaa tcagggatgt
    16741 cagcgctaaa agcgttgccc agttcacggg catcctgggt acctttaacc gtaatacctg
    16801 ttttatctga caagcattga ttggttgaac gatcgcaacg ttcagcatgg cgaaacaaaa
    16861 cgacaaccgg gtgctgctgt gccagtctgg ccaatgtttt attgtcgata cgtggcaaac
    16921 cattgctact ccaggcggca tgagtaccca gtccggcaat tgcagcgagc gccagtaaaa
    16981 tgatgaaata tttttttgac ttcaatgatg agcggcaaaa agctaacacg taaactccac
    17041 ctatagacaa gcgcaaccag acaattaccg taaaattgag cgacatttct ggcgataatt
    17101 agcagttggt gtaatattaa aaatcctacg atgtcggcaa aatgcctcaa aattttgcca
    17161 aatgcaaagc ctaaataaga aaaaatataa aaatttcaat atttacgtct aatattagtt
    17221 tcttaaggtt aagttaatat tctatcctta aaatttcgct ccaaatggca aaatatacac
    17281 aacactcttt atagcaaata taagtggaca ggtattcaat ggcggaagga aaagcaatgt
    17341 cagaattttt gcctttttcg cgaccagcaa tgggcgtgga ggaactcgct gcagttaaag
    17401 aggttctcga atccggttgg ctcacaaccg gtccgaagaa tcaggcgctt gagcaagcct
    17461 tttgccagtt gacgggaaat cagcatgcca tcgcggtcag ttcagccacc gccggaatgc
    17521 atatcacgct aatggcgttg gaaattggca agggcgatga agtgattacg ccttccctga
    17581 cctgggtttc aaccctcaat atgatttcct tgttgggtgc aacgccggta atggtggatg
    17641 tcgaccgcga tacgctgatg gtcacgcctg aagcgatcga gtcagccata acgccacgca
    17701 ctaaagccat cattccggtg cattatgccg gtgcgccagc agatattgac gccattcgcg
    17761 ccattggcga acgttacggc atcgcagtta tcgaagatgc tgcccatgcc gtcggtacgt
    17821 attacaaagg gcgacatatt ggcgcaaaag gtaccgctat tttttcattt catgccatta
    17881 aaaatattac ctgtgcggaa ggtggcctga ttgtaactga taatgaaaac cttgcccgcc
    17941 agctacggat gctgaaattt cacggtctgg gtgtcgatgc ctatgacaga caaacctggg
    18001 gccgtgcacc gcaggctgaa gtcttaacac cgggctataa gtacaatctg accgatatta
    18061 acgccgcaat tgccctgaca cagttagcaa aattagagca cctcaacacc cgtcggcgcg
    18121 aaattgccca gcaatatcag caagcactgg cagctctccc ctttcagcca ttaagccttc
    18181 ccgcctggcc gcacgttcac gcctggcatc tgtttattat tcgtgtcgat gaacaacgtt
    18241 gtggtatcag tcgcgatgcg ttgatggaag cgttaaaaga aagaggcatt ggtaccgggt
    18301 tacatttccg cgccgctcac acacaaaaat attatcgcga gcgttttccc acgctgtcgt
    18361 taccgaatac cgaatggaat agcgaacgca tctgttcttt gccgctgttc ccggatatga
    18421 ctaccgccga tgccgaccgt gtcatcacag cccttcagca actcgcagga caataagcca
    18481 tgtttgaaat ccaccctgtt aagaaagtct cggtggttat tcccgtttat aacgagcagg
    18541 aaagcttacc ggaattaatc aggcgcacca ccacagcctg tgaatcgttg gggaaagagt
    18601 atgagatcct gctgattgat gacggcagta gcgataattc cgcgcatatg ctggtcgaag
    18661 cctcacaagc ggagaacagc catattgtgt ctattttgct taaccgcaat tacgggcaac
    18721 attcagcgat tatggcggga ttcagtcacg ttaccggcga cttaattatt acccttgatg
    18781 ccgatctcca gaatccgcca gaagaaatcc cccgcctggt ggcaaaagcc gatgaaggtt
    18841 acgacgtggt agggactgta cgccagaacc gccaggacag ctggtttcgt aaaacagctt
    18901 cgaagatgat taaccggctt attcagcgca ccaccggcaa agcgatgggt gactacggtt
    18961 gtatgctgcg cgcctatcgc cgtcatattg tcgatgcgat gttgcactgc catgaacgta
    19021 gcacctttat cccgattctg gcgaatatct tcgcccgccg tgccattgaa attccagtac
    19081 atcattccga gcgtgagttt ggtgaatcca aatacagttt tatgcgcctg attaatttga
    19141 tgtacgacct ggtgacctgc cttaccacaa cgccgctacg tatgctgagt ctgctcggca
    19201 gcattattgc gattggaggt tttagcattg cggtgctgct ggtgatttta cgcctgacct
    19261 tcggaccaca atgggcggca gaaggcgtct ttatgctatt tgccgtgctg tttactttta
    19321 ttggcgctca gtttatcggc atgggattac tcggtgaata tatcggcagg atctacaccg
    19381 atgtccgcgc ccgcccccgc tattttgttc agcaagttat ccgtccatcc agcaaggaaa
    19441 atgaataatg aaaaccgtcg tttttgccta ccacgatatg ggatgcctcg gtattgaagc
    19501 tctgctggct gccggttacg aaattagcgc catttttacc cataccgata atcccggtga
    19561 aaaagccttt tatggttcgg tggctcgtct ggcagcggaa agaggcattc cggtttatgc
    19621 gccggatgac gttaatcatc cgctgtgggt ggaacgcatt gcccaactgt cgccagatgt
    19681 gattttctct ttttattatc gccatcttat ttgcgacgaa attttgcagc tcgctcccgc
    19741 aggtgcattt aatctgcatg gttcgctgtt accaaaatat cgtggtcgcg cgccgctgaa
    19801 ctgggtgctg gtcaacggtg aaacggaaac tggcgttaca ttgcaccgaa tggtgaaacg
    19861 tgccgatgcc ggggccattg tggcgcaact gcgcattgcc attgcgccag acgatatcgc
    19921 tattacgctg catcataaat tgtgccatgc cgcgcgccag ctactggaac agacattacc
    19981 cgccattaaa cacggtaata ttctggaaat cgcccagcgc gaaaacgaag ccacctgttt
    20041 tggtcgcaga acgccggatg acagtttcct tgaatggcat aaaccggcat ccgtactgca
    20101 caacatggta cgtgccgttg ccgatccgtg gccgggtgcc ttcagctatg ttggcaatca
    20161 gaaattcacc gtctggtcgt cgcgtgttca tcctcatgcc agcaaagcac agccggggag
    20221 cgtgatttct gttgcgccac tgctgattgc ctgtggcgat ggcgcgctgg aaatcgtcac
    20281 cggacaggcg ggcgacggca ttactatgca gggctcgcaa ttagcgcaga cgctgggcct
    20341 ggtgcaaggt tcacgcttga atagccagcc tgcctgcacc gcccgacgcc gtacccgggt
    20401 actcatcctc ggggtgaatg gctttattgg caaccatctg acagaacgcc tgctgcgcga
    20461 agatcattat gaagtttacg gtctggatat tggcagcgat gcgataagcc gttttctgaa
    20521 tcatccgcat tttcactttg ttgaaggcga tatcagtatt cattccgaat ggattgagta
    20581 tcatgtcaaa aaatgtgatg tcgtcttgcc gctggtggcg atagccacgc cgattgaata
    20641 tacccgcaac ccgctgcgcg tatttgaact cgattttgaa gagaatctgc gcattatccg
    20701 ctactgcgtg aagtaccgta agcgaatcat cttcccgtca acttcagaag tttatgggat
    20761 gtgtagcgat aaatacttcg atgaggacca ttctaattta atcgtcggcc cggtgaataa
    20821 accacgctgg atttattcgg tatcaaaaca attacttgat cgggtgatct gggcctatgg
    20881 cgaaaaagag ggtttacagt tcaccctctt ccgcccgttt aactggatgg gaccgcgact
    20941 ggataacctt aatgcggcac gaatcggcag ctcccgcgct attacgcaac tcattctcaa
    21001 tctggtagaa ggttcaccga ttaagctgat tgatggcgga aaacaaaaac gctgctttac
    21061 tgatattcgc gatggtatcg aggcgttata ccgcattatc gaaaatgcgg gaaatcgctg
    21121 cgacggtgaa attatcaaca ttggcaatcc tgagaacgaa gcgagcattg aggaactggg
    21181 cgagatgctg ctggcgagct tcgaaaaaca tccgctgcgc catcatttcc caccgtttgc
    21241 gggctttcgc gttgtcgaaa gtagcagcta ctacggcaaa ggatatcagg acgtagagca
    21301 tcgtaaaccg agcatccgca atgcccaccg ctgcctggac tgggagccga aaattgatat
    21361 gcaggaaacc atcgacgaaa cgctggattt cttcctgcgc accgttgatc ttacggataa
    21421 accatcatga ccaaagtagg cttacgcatt gatgtcgata cctttcgtgg cacccgtgaa
    21481 ggcgtgccgc gtctgctgga aatcttgagt aagcataata ttcaggccag catttttttc
    21541 agcgtcggcc cggacaatat gggccgccat ctctggcgac tggtgaagcc acagtttttg
    21601 tggaagatgc tgcgctcaaa tgcggcatcg ctttatggct gggatatttt actggcaggt
    21661 acggcctggc caggtaaaga gattggtcat gccaatgccg atatcattcg tgaagcggct
    21721 aaacatcacg aagtcggcct gcacgcctgg gatcaccatg cctggcaagc ccgtagcggt
    21781 aactgggatc ggcaaacaat gatcgacgat attgcacgcg gtcttcgcac tctggaagag
    21841 attatcggtc aaccggtaac ctgttctgcc gctgcgggct ggcgtgccga ccagaaggtg
    21901 atcgaagcaa aagaagcgtt ccatttgcgc tacaacagcg attgtcgtgg ggccatgccg
    21961 ttccgtccat tgctcgaatc aggaaaccct ggcactgcgc aaattccggt gaccttaccc
    22021 acctgggatg aagtgattgg tcgggatgtg aaagcagaag attttaacgg ttggttactc
    22081 aaccgcatcc tgcgagataa aggcacgccg gtttatacca ttcatgcaga agttgaaggc
    22141 tgcgcttatc agcataattt tgtggatctc ctcaaacgcg cagctcagga aggcgtgaca
    22201 ttttgccctt taagcgaact gttatcagag acgttgccgc tcggacaagt tgttcgcgga
    22261 aatattgccg gacgtgaagg ctggctgggt tgccaacaaa ttgcgggtag tcgctgatga
    22321 aatcggtacg ttaccttatc ggcctcttcg cgtttattgc ctgctattac ctgttaccga
    22381 tcagcacgcg tctgctctgg caacccgatg aaacgcgtta tgcggaaatc agtcgagaaa
    22441 tgctggcatc cggcgactgg attgtgcccc aactgttagg gctacgttat ttcgaaaaac
    22501 ccattgccgg atactggatt aacagcattg ggcaatggct atttggcgcg aataactttg
    22561 gtgtgcgggc aggcgttatc tttgcgaccc tgttaactgc cgcgctggtg acctggttta
    22621 ctctgcgctt atggcgcgat aaacgtctgg ctctactcgc cacagtaatt tatctctcat
    22681 tgtttattgt ctatgccatc ggcacttatg ccgtgctcga tccgtttatt gcattctggc
    22741 tggtggcggg aatgtgcagc ttctggctgg caatgcaggc acagacgtgg aaaggcaaaa
    22801 gcgcaggatt tttactgctg ggaatcacct gcggcatggg ggtgatgacc aaaggttttc
    22861 tcgcccttgc cgtgccggta ttaagcgtgc tgccatgggt agcgacgcaa aaacgctgga
    22921 aagatctctt tatttacggc tggctggcgg ttatcagttg cgtactgacg gttctccctt
    22981 ggggactggc gatagcgcag cgggagcctg acttctggca ctattttttc tgggttgagc
    23041 atattcaacg ctttgcactg gatgatgccc aacatagagc tccgttctgg tactacgtgc
    23101 cggtcatcat tgccggtagc ctgccgtggc tgggattact ccccggtgca ctgtacacag
    23161 gctggaaaaa ccgcaagcat tccgcaaccg tctatttgtt gagctggacg ataatgccgc
    23221 tgctgttttt ctccgtcgct aaaggtaaat tgcccaccta tattctttcc tgctttgcat
    23281 ctctggcaat gctgatggcg cattacgctt tgctggcagc aaaaaataat cctctggcgc
    23341 tgcggattaa tggctggatt aacatcgctt ttggcgtcac tggcattatt gccacatttg
    23401 tggtctcccc gtggggacca atgaacacgc cggtgtggca aaccttcgag agctataaag
    23461 tcttttgtgc ctggtcgatt ttttcgctat gggcattttt cggctggtac accttaacaa
    23521 acgtcgaaaa gacctggcct tttgccgcgc tttgcccgct ggggctggcg ttgctggtag
    23581 gattttcaat tcctgacaga gttatggaag gaaaacatcc gcaatttttt gtcgagatga
    23641 cacaagaatc acttcagcca agccgctata ttcttactga tagcgtcggt gttgccgcag
    23701 gtctggcatg gagcctgcaa cgcgatgaca tcatcatgta tcgccagaca ggtgagttga
    23761 aatacggcct taattatccg gatgcgaaag ggagatttgt cagcggtgat gagttcgcaa
    23821 actggcttaa tcaacatcgt caggagggga ttattactct cgtgctttcg gttgaccgcg
    23881 atgaagatat caacagtctc gccattccgc ccgcagatgc catcgatcgt caggagcgtc
    23941 tggtgctgat tcagtatcgt cccaaatgat ctggctaaca ttagtctttg ccagcttgct
    24001 tagcgttgcc gggcagttgt gtcagaaaca ggcaacctgc tttgtggcga taaacaaacg
    24061 gcgcaaacat atcgtgctgt ggctgggact ggcgctggct tgtcttggtc ttgccatggt
    24121 gctctggctg ctggtcttgc agaacgtacc ggtaggcatt gcctacccga tgttaagtct
    24181 gaattttgtc tgggtgacgc tggctgcagt aaaactgtgg cacgaaccgg tatcgccgcg
    24241 tcactggtgt ggggtggcgt tcattattgg tggcattgtg atcctcggga gtacggtgta
    24301 atgggcctga tgtggggatt attcagcgtc attattgcct cagttgcgca attaagcctg
    24361 ggttttgcgg cgagtcatct gccgccgatg acgcacttat gggattttat cgcggctctg
    24421 ttagcttttg gcctggatgc ccggatactg ttactcgggc tgctgggtta tctgctttcc
    24481 gttttttgtt ggtataaaac gctacataaa cttgcgctaa gcaaagccta tgccttgctc
    24541 agtatgagtt atgtgctggt atggattgct tcaatggtac ttcccggctg ggaagggact
    24601 ttttcgctga aagcactact gggagtagcc tgtattatga gcgggttgat gctgattttc
    24661 ctgcccatga caaaacaacg ttactgagtt ttccctgcca ctttacactg ccgttcccac
    24721 tcatcggggc tataactgct tgccgagagg actttcaccg tatgcagctt ttcacgatta
    24781 atacaataaa gcgcattctg caaaggcgag agtaaatccc ccactttcac ggcgaagtca
    24841 ctcttcactt cggcgatcat ttttatcgcg ccgccagcat cgcagagcat aagtacatgt
    24901 ctgttatctt gtttattgca gcacgatttt ttgaccagcc attccattgc attatcctgt
    24961 ttgctaagag ttttcacatc aatttacaga ttaacagata aactctttat caacggcaat
    25021 ggaatggcag aaatgagaag tgaaacggag ggttaattat tgctgacgtt gcacccactc
    25081 ttttagcgcc tgacgtgaaa ttttaatacc gccgtttttc agttcaggcg gcaacgttaa
    25141 ccaacgcacc ggttgctgaa aactggccag cttatctttc acccattcac taagatcaac
    25201 gctctcgtgg tcatactcca tcaccgccac cggtcgatga ccaaactcct tgtcggcaac
    25261 ggggacgata aacacctgca aaaccgcagg atgtgcagca attacgcgct cgacttcttc
    25321 cggctgaata ccctcaccgc cactgaagaa cagattgtct aaacgtccga caatggtcag
    25381 cttgccatta tgcatctcac cgcgatcgcg cgtagcgtac cagccttcgt cattaaccag
    25441 tgaaaccagt tgcccgttac gccagtaacc ttctgccata ctggcagccc gcagccacac
    25501 ttcattatta acgattttca cttcccgacc cggcagcggc gaaccaacgt ctgccaggcc
    25561 gtcggcttct ttcgcacaca ccgtggaggc aaactcggtc agaccatagc cgcaaaagca
    25621 acgaatcccc tgctcgcgcg cctgttccgt caactcgacc gggatagccg cgccgccaag
    25681 taacaccgct ttcagggaaa cggaactgcg gttaaccagc aaacgccaga gttgtgttgg
    25741 caccagtgaa gcgtgagtac agcctgccag catttgctcc aatggctgtt tatcacgcac
    25801 cgtcatccgc gcaccagcgt ataaccagcg ccacataatt ccctgaccgg agacgtgaaa
    25861 cagcggtaaa gagagcaacc agtcatcgtg atcgccaaac ggaatcaacg ataacacccc
    25921 ttcggcactg gcaagatggg cctgataagt atggacagcg gctttcggca acccggtaga
    25981 acccgaggtc aacgtcattg agcacagacg cgtcggctgc cacgtagcgg catgtgcgcc
    26041 ttcaacccgc tgaatgtgca gcgacgttaa cgccggaaac gtgttttccc catccggcac
    26101 cagcgcaaat tgcagcgtca gattgggcag caattcttca agcaacggtt gcggcagctg
    26161 agggttcacg ggcaacaccc gcgccccgca ttgcagtaac gccagccagg cgagcagcgt
    26221 ttgcggcgta ttccacgccc gcaacatcac gccgctgccc tcaacaacgc cctgcgccgc
    26281 aaagcctgag gctaattcat cgacgcgagc acaaagctcg cgccagttaa gttgctcgtc
    26341 attaagacgt aaggcgatgg cttctccccg cacttgccgc cagtgacgcc acggccagtc
    26401 agagaagatc ataacaaccg ctccagtgca tcaacttcca cgacaggcag cgtgctaccc
    26461 ggccagcgac gtacctgctg cgcctgcatc agatccagcg tgtccagccc tggaatggtg
    26521 tccggcgtta accaggcggc aatccgcgcc agttgcgtta agcctaagct cgattcaatg
    26581 gaagaactga tcaccgccgt cagccccagc gcgtgcgccg cctgtacctg ctcgcgtact
    26641 ttctccagac tgcccgtgag cgtgggtttg ataactaccg cgcgcacgcc ctcttcagcc
    26701 acaaaggcaa aatccggctc gcgcaagctt tcatcccagg caatggcaat gccggtttca
    26761 cgggcaaacg ctcgcgaatc atcgcgggtt ttgcacggct cttcgagaaa cgcgatgcgg
    26821 tggcgataat ccgggttaac atatttggca aactgctggc ctttcagcgg tgtccaggcg
    26881 cgatttgcgt caagacgcaa atgcagatcc ggaattgcct ccagcaacag attaaccacc
    26941 atgccgtcgc gcacggcttc gtacaatccc actttgacct tcgccacttt ctcgcctggc
    27001 atatcagcaa gtttgaggat cagatcgtca ggatcgccat tacacagtgg tgccgcacgg
    27061 taattggccg cctgcgggag cgtatctgcc agctccgcca atgcacagct tacgccaaag
    27121 gcaacggaag gcatctgcgg tagctcgcaa tcgcctgcca gccagttatt tacccaggca
    27181 agcagcacgc tttgcgcctc ttcccaggtt tcctggctga agcccggcag tggggagatc
    27241 tccccccacc cttcgcgctc gccctcacgc aggcaaacgt acagcccgtc gcgggttttt
    27301 aaccgcctgt cgcgcagaac cacccccgcg tccatgggga tctgccagcg gtatacctgc
    27361 gcgctacgca ttacggattc cgtttaaatt tgctgaaatc aggctgacgt ttctggttga
    27421 aagcgttgcg accttcctga ccttcttccg tcatgtagaa cagcatggtg gcgttgcccg
    27481 ccagctcctg cagccccgcc tgcccgtcac agtcggcgtt cagcgcagct ttcaggcagc
    27541 gcagcgccat cgggctgttt tgcagcattt cgcggcacca acggacggtt tctttttcca
    27601 gatccgccag cggtaccacg gtgttgacaa ggcccatatc cagcgcctgt tttgcgtcgt
    27661 actgacggca caggaaccag atttctcgcg cttttttctg cccgacgata cgagccatgt
    27721 aggaagcgcc ccagccgccg tcgaaggaac cgactttcgg gccagtctga ccgaagatgg
    27781 cattatctgc tgcgatagtc aggtcgcaca tcatgtgcag aacgtgacca ccgccgatgg
    27841 agtagccagc caccatcgcg acaaccggtt tcggacaggt acggatctga cgctggaagt
    27901 ccagcacgtt caagtgatgt acgccggaat catctttata gccgccgtaa tcaccacgca
    27961 ctttctggtc accaccggag cagaacgctt tatcgcctgc gccagtcaga atgatcacgc
    28021 cgatattgtc gtcataacgc gcatctgcca gtgcctggat catctctttt accgtcagag
    28081 gacggaaggc attgcgcacc tgcggacgat taatggtgat ttttgcgata ccgtcggtgg
    28141 atttttcata acgaatgtcc tcgaaacctt cggagcagtc gtgccattca accggtgcgt
    28201 aaagcattgc ttcatcagga taaatcatat tgtgtccttt agtcagaaac gcaagatctg
    28261 cgccagactt gcgattacgc cagcgggatt ttcccgatgc gcgttatgtc cggcgcgagg
    28321 aatgacatgg cagtcggcag ccagttccgc cgccagggcg cggaatttgc tgtcacgttc
    28381 accacataaa taataaaacg caaatgtgcg ggcgctaagg ttagcacgta aatcaggctg
    28441 gacggcgaga gaagtcgcct ccagcatggc ggcaagggtt gcgccattat tgttgctgcg
    28501 cagcgccacc agctcccggc gttgatcgtc attgagcgag gcaaaaacag gctgttgata
    28561 ccagtcggca aataccgccg ttaacggttc tgtgcgaaaa cgctgcgccc attggcgatc
    28621 ggaacgctga cgttccgcac gttgttcagc attttgcagc cccggatgcc cgccttcgac
    28681 aataacccca caaagccccg ccagcccctg gcaagccgcc atcatcgcca cccgtccgcc
    28741 aagcgagtac cccactagcc aaaagtcaag gatgttgtaa ctaaccaagg ttttacgcag
    28801 taagtcggtg acatcatcaa atccatcgac gctaatcgcc gccgaaccac catgacctgg
    28861 gagatcaaca tacaaccgtg agtagtcggc aaacgcctcg cccacttctt gccattcgtg
    28921 gcaatcgccg gaaaaaccgt gcaaaaacac cagccagggt aaacctggtt ttccgtgttt
    28981 tgcctgcgcg tgcaggatca taaatggctt acctgcgcca gaagttgctg gagcgtttgc
    29041 gcaccatcgg tgtcgttaac caccatttca atcaccgtgg tggttggcgt gcgccaggcg
    29101 tcggcaaatg ccgtttcaag ttcctgccag ttttgcggac gatgatattt cagctcgaac
    29161 atcgcggcgg cgtgctcaaa atggacgttt tgcggcatca gatagaaacg ctcacgctcg
    29221 ctttgcggcg ttggcaacag cgagaaaatt tgcccgccgt tgttgttcac cacaattaat
    29281 accagcggcg cagaaacctg acgcaataac gccagcgcgt tgagatcgta aagtgcggag
    29341 agatcgccca caatcgccag cgtcggtttg ccgcttgccc gctgaacgcc tgcggcggtc
    29401 gaaagcagtc cgtcgatacc gctggcccct cggttgctgt acaccgggta acctgctgga
    29461 agttgcgaaa gcgcatcaat cagacgtacc accaggctgt taccaacaaa caattgcccc
    29521 tgttcaggca gatagtcgca gatgcgatgc gccagttgcg cttcgccaaa cgcatcacgg
    29581 cgggcaataa ccgcctgcat tgcctgttcc gccaggcgcg ggatttcaac gcaccagggc
    29641 tggcgttttt ctgccggatg cagctccagc cagtcggcaa tattggcaat taagcgacgt
    29701 ccgcgatggt gtgccggatc aagtcgccct tcaatgtcat caacaatcca gtactcttct
    29761 ggttcacagc ttgcctgcca ttgcaggagc cgtttgcccg tcaggctgct tcccagttgc
    29821 accacaattt gcgcctgctg cagctcgctg gtcgctttgg cattgcctaa ccaaagatcg
    29881 gcacacggca gcggctgccc ggtttgtgac agcacatcgc caatcagcgg ccagccaaga
    29941 gtttgcgccc acagggcaac ttttttgccc tcttccgcac tcatgcgccc ggcaaccacc
    30001 acgccgcgct tttgtcgcca gaagaaccag tcgcgctgtt tttcactttc cagacgaggc
    30061 gcttcacgca gccacggttt gtcgtcctgc caccagtcac ccagacgctg ttgccagcta
    30121 agcccggtat cgtccatttc gccatacagc ggttcagcaa acgggcagtt gatatggact
    30181 ccccccgcat gaagcgtacc gagagcgtgg tcgatggtag aaaccagcca acgtgcgggg
    30241 atatcccggg tcgggcgcgg caatgaaata ctgtgcgtgg ggtgagaggc gaacattccc
    30301 ggctggcgaa ttgcctgatt cgcgccgcag tcaattagct ccggcgggcg atcggcggtt
    30361 aacaggatca gtttttctcc ggttaacccg gcttcaatca gtgcaggata gagatttgct
    30421 accgccgtgc cggaggtcac aatcaccgcc accggctgct tgctgacttt cgccagcccc
    30481 agcgccagat gccccaaccc acgctcatcg aaatgggtgt ggtgaatgaa tgcggaattc
    30541 tccgccgccg ctaacgttaa cggtgtagaa cgcgagccag gggcgataca gatgtgtctg
    30601 acgccgtgac gcgttaatgc ttccagaatg accgccgccc agcgtcggtt aaatgcgctt
    30661 actgacatga gtttgtccgg tatcaatatt gcggctaagt ataaggagct acaaaaatag
    30721 attattgata tgaatcggta atgatgcgac tcattactat tccatttgta ataaagtacg
    30781 cagccctgcc gctttgttgt cgatttcctg ccactcttgc tcggggtcgg aaccacggac
    30841 aatgcccgcg ccagcatata gccgcacgac attgccgctg atttttgctg aacgcaggga
    30901 aacgcagaat tcgctttgtt gtaatgagag atagcccgca gaaccggcgt accattctcg
    30961 ggtgaacggt tcgtgacggg cgataaactg tcgcgccaga tcgcgcggta agccagcaac
    31021 tgctgccgtt ggctgcaact gatgtaaaca gatcacatca tccgctttgt tgagtgaagt
    31081 ccagatacag cggcgaagat gctgcacttt acgcagacgc agtacctgcg gcggtaaaac
    31141 atccagcgtc tgggtatcgg cctgtaatcg ttggcagata tcttccacca ccagcatgtt
    31201 ctcgcgctgg tttttatcat ccgccatcag ccactctcct aactgctgcg cctgcttatc
    31261 atcaggatta tttgctactg ttcccgccag cgcttcagta cgcagcgctt tgtcacgccg
    31321 ccgccataac cgttccggtg aagagccaag aaaagcattt tcgccatcaa aggccatgta
    31381 aaaatggtag caattcagat tcagtcgacg actggcagcc atcatcgccg ccgcgttgac
    31441 cggacttgcg aaatgcaggt cagttgcccg agcgagcacc actttgtcga gctccccttc
    31501 ggcgatggtt ttcgttgcca gttcgattaa ttgcgtccag cccgttttgt ccggccagtg
    31561 ttgttctcgc gtggtggtta aatgtaaccc aggcaagggc ttgatactca ccagtgtggc
    31621 gataaattct cttgcctgaa tcgcatcgtg ctgaagggag ctttcgctga atagcgtcag
    31681 ccgcagcgtg gctttaccgc cacagcgtcg ccattccagg cgtggtaaaa gtaaattgcc
    31741 ctgcgacggg tcaaacgcat tcagccccca aatgcgtaag tcggcgtgtt ccgggtgctg
    31801 gcgaagaaaa cgttgtgcct ggtccaacga cgtaaaacgg gtaatcgcgc ccaggacggc
    31861 agcttcttca tcaccattac gttgttgcca gtagaattgc gggtacgttt gctgactggc
    31921 cagccagctc aaggcatcaa aagcgtcttt gagagggaaa ggaatatcga taacccgaat
    31981 gccgggtgtc gccggaatct cttgcgacaa atggcgcagt agattttcca gcgccgtagt
    32041 aagtgattgc acgcggacct ctccctgtta aaagcctcac attatacggg gtactacaaa
    32101 aaaaatgcag taccccggtg tagggaggtt ttaacggcgt gccagcaaca gtcctagtac
    32161 cagcccgacg gccgcgccca caccaattcc ttgccagggt ttttcgtgga cgtagtcatc
    32221 agcacgataa acagcctgct tcgcccgata gtaataactg tctgaagcct ggctaacccg
    32281 ttttttcaca tcatccagcg ctttttctgc acgcgctttc agctcaacat atttctgatc
    32341 ggcgggatcg ccagaggagc ggagcacctc ttccagtgtt tcactaagca gcgtcaggtc
    32401 gtcatcgata cgtgtatcac caaactgatt agacattctc gttctccatt tgcgtaaaac
    32461 ctgtcactaa ctatagacaa gggttgttga ttacgcctga attacctcgc gtgccatccc
    32521 aatgtgtggg ataccatctt cttcatagac ctccgtcaca gggataaaac cgaaactctg
    32581 gtagaagttt tgcagatgcg cctgcgcccc gaggtaaaca ggcttatcag gccagtgatg
    32641 cgtgcaggtg tcgagggttt tactcatcag ttgctgcccc actttttcgc cacgcaacgc
    32701 ttcactgaca atcacccgac ctataacgac cggctcaaga tcatcatcac ttttcagaat
    32761 cctcgcatac gccaccagtt catcattttt ccaaccgaga atatggcgat tatcccccgt
    32821 caaatcatca ccatcgatat cctgataagg gcaattctgc tcgacaacaa acaccgcgca
    32881 acgcagttgt aataaggcat aaagctggga aaccgataat tcagagtgat gcagatcttg
    32941 ccattcaatc ataatgctct ccttttagat gtatgcctta tactagccgg aatatttttt
    33001 gaaacgtgat gaactcatgg aattaatttt tttaggtact tcagccggtg tgccaacccg
    33061 cacgcgcaat gtcacggcaa tattgcttaa cctgcaacat ccgacccaga gcggactttg
    33121 gttgtttgac tgcggtgaag gcacccagca tcagctactg cataccgcct ttaaccctgg
    33181 aaaactggac aagattttta tcagtcacct tcatggcgat catctttttg gtttacccgg
    33241 cttgctgtgc agtcgttcta tgtcaggcat tatccaaccc ttaacgattt atggtccgca
    33301 aggtatccgt gaatttgtgg aaaccgcgct gcggattagc ggctcatgga ccgattatcc
    33361 gctggaaatt gtcgaaattg gcgctggcga aattctcgat gatggcctgc gcaaagtaac
    33421 cgcttatccg ctggaacacc cactggaatg ttatggctat cgtattgaag aacatgataa
    33481 accgggtgca ttaaatgccc aggcattaaa agctgctggc gtgccgcctg gcccactgtt
    33541 tcaggaatta aaagcgggca aaacaatcac gctggaagat ggaaggcaga ttaacggcgc
    33601 agattactta gctgctccag tgccaggtaa agcgctcgct attttcggcg ataccggccc
    33661 ctgcgatgcc gcacttgacc tggctaaagg tgtcgatgtc atggtgcacg aagcgacgct
    33721 ggatataacc atggaagcca aagccaatag tcgcggccat agctctacac gccaggctgc
    33781 gacactagcc cgtgaggctg gagtcggtaa gctaatcatt acccacgtca gctcgcgcta
    33841 tgatgacaaa ggttgtcagc acctgttacg tgaatgcagg tcaattttcc cggcgactga
    33901 actagcgaat gatttcaccg tgtttaacgt ttaactctgc ttattattaa aaacagggcg
    33961 aaacttgccc tgttatcgca acccgcgcta catatatcca cccacacggg catattgagc
    34021 gatttttgat atttattcat ctccttacgc actatattca gagcaataag ttgcctcttt
    34081 ttatcttcat tcagcacaac ctttgcaact aaaaggagcc catgatggtt acagttgtca
    34141 gcaattattg tcaattatct caaacccaac tcagtcagac atttgcagaa aaatttactg
    34201 tgaccgagga attactgcag tctttaaaaa aaacagcgtt atccggagat gaagaaagta
    34261 ttgagttact gcataatatt gcgttaggtt atgatgaatt tggaaaaaaa gctgaagata
    34321 ttctttacca tattgttaga aacccaacaa atgagaccct atcgattatc cgacttatta
    34381 aaaatgcctg tttaaaatta tataatttgg cacataccgc aaccaactcc caccttaaac
    34441 caactggtcc ggataattca gatgttctcc tgttcaaaaa gctattctcc ccttcgaaat
    34501 taatgacaat tatcggtgat gaaattcctc ttatatctga aaaacagtcg ctttcaaagg
    34561 tgcttttaaa tgatgagaat aatgaactga gtgatgatac aaacttctgg gataaaaatc
    34621 gtcaattaac cacagatgaa atagcttgct atcttcagaa gatcgccgct aatgcaaaaa
    34681 atactcaagt caattatcct actggtctct acgtccccta ctccaccaga actcacctgg
    34741 aagacgctct caatgaaaat attaagagcg atccatcatg gccgaatgaa gtccagttat
    34801 tccccataaa tactggcgga cactggatat tagtttcgct acagaaaata gtaaataaaa
    34861 aaataataaa ctacaaataa aatgcgtcat attcaactca ttgcgtgcac taggccatga
    34921 taaagaaaat tcacttacgc gtgtcattaa tagttttaat tctgaactca tgggagaaat
    34981 gtcgaataat aatataaaag ttcatttaaa tgaaccagag ataatatttt tacatgccga
    35041 tcttcagcaa tacttaagcc aaagttgcgg tgcgtttgtg tgcatggcag cccaggaagt
    35101 gattgaacaa agggaaagca attctgacag cgccccctat acgttattaa aaaactatgc
    35161 tgacagattt aaaaaatatt cagcagaaga gcagtacgaa attgattttc aacatcgact
    35221 ggtaaacaga aattgttatt tagata
//
LOCUS       DAZUDJ010000053        33297 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.053, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000053 DAZUDJ010000000
VERSION     DAZUDJ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33297
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.053"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..242)
                     /locus_tag="ACHY1N_003334"
     CDS             complement(<1..242)
                     /locus_tag="ACHY1N_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HFS4045581.1"
                     /translation="MDQKLLTDFRSELLDSRFGAKAISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSI"
     gene            complement(453..1850)
                     /gene="ccp"
                     /locus_tag="ACHY1N_003335"
     CDS             complement(453..1850)
                     /gene="ccp"
                     /locus_tag="ACHY1N_003335"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HFS4045582.1"
                     /translation="MKMVSRITAIGLAGVAICYLGLSGYVWYHDNKRSKQADVQASAV
                     SENNKVLGFLREKGCDYCHTPSAELPAYYYIPGAKQLMDYDIKLGYKSFNLEAVRAAL
                     LADKPVSQSDLNKIEWVMQYETMPPTRYTALHWAGKVSDEERAEILAWIAKQRAEYYA
                     SNDTAPEHRNEPVQPIPQKLPTDAQKVALGFALYHDPRLSADSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNVEQFWDGRAATLQDQAGGPPLNPIEMASKSW
                     DEIIAKLEKDPQLKAQFLEVYPQGFSGENITDAIAEFEKTLITPDSPFDKWLRGDENA
                     LTAQQKKGYQLFKDNKCATCHGGIILGGRSFEPLGLKKDFNFGEITAADIGRMNVTKE
                     ERDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGKELPQEDVDDIVAFL
                     HSLNGVYTPYMQDKQ"
     gene            2255..3904
                     /gene="treF"
                     /locus_tag="ACHY1N_003336"
     CDS             2255..3904
                     /gene="treF"
                     /locus_tag="ACHY1N_003336"
                     /EC_number="3.2.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004555 - alpha,alpha-trehalase activity
                     [Evidence IEA];
                     GO_process: GO:0005993 - trehalose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HFS4045583.1"
                     /translation="MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     TGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRY
                     LWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGIL
                     ASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKMI
                     EKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            complement(3955..4557)
                     /gene="yhjB"
                     /locus_tag="ACHY1N_003337"
     CDS             complement(3955..4557)
                     /gene="yhjB"
                     /locus_tag="ACHY1N_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="HFS4045584.1"
                     /translation="MQIVMFDRQSIFIHGMKISLQQRIPGVSIQGASQADELWQKLES
                     YPEALVMLDGDQDGEFCYWLLQKTVVQFPEVKVLITATDCNKRWLQEVIHFNVLAIVP
                     RDSTVETFALAVNSAAMGMMFLPGDWRTTPEKDIKDLKSLSARQREILTMLAAGESNK
                     EISRALNISTGTVKAHLESLYRRLEVKNRTQAAMMLNISS"
     gene            5077..5976
                     /gene="rcdB"
                     /locus_tag="ACHY1N_003338"
     CDS             5077..5976
                     /gene="rcdB"
                     /locus_tag="ACHY1N_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417978.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4045585.1"
                     /translation="MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQL
                     GTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSELDGLFQQDATSISGKLRIDIPPGI
                     AKSLLLPRLSEFLYLHPGIELELSSHDRPVDILHDGFDCVIRTGALPEDGVIARPLGK
                     LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGG
                     MLTVNSSENYLAAGLAGLGIIQIPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQR
                     RELSRRVNLFMQWLAGVMKEHLD"
     gene            6025..7038
                     /gene="yhjD"
                     /locus_tag="ACHY1N_003339"
     CDS             6025..7038
                     /gene="yhjD"
                     /locus_tag="ACHY1N_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HFS4045586.1"
                     /translation="MTQENEIKRPTQDLEHEPIKQLDNSEKGGKVSQALETVTTTAEK
                     VQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPML
                     LQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAI
                     RAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALH
                     LNSIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVI
                     KIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGK
                     TQP"
     gene            7449..8771
                     /gene="yhjE"
                     /locus_tag="ACHY1N_003340"
     CDS             7449..8771
                     /gene="yhjE"
                     /locus_tag="ACHY1N_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4045587.1"
                     /translation="MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATA
                     AVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIGSAVFGHFGDRVGRKATLVASLL
                     TMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHESPVFEKVAKAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFST
                     AAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASI
                     LGASVAPYIAAWLQANYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL"
     gene            complement(9005..11065)
                     /gene="yhjG"
                     /locus_tag="ACHY1N_003341"
     CDS             complement(9005..11065)
                     /gene="yhjG"
                     /locus_tag="ACHY1N_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HFS4045588.1"
                     /translation="MSKAGKITAAISGAFLLLIVVAIILIATFDWNRLKPTINQKVSA
                     ELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHAEDIILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTVWLPWIKLEKPDARLIRLSEKNNNWTFNLANDDNKDANAKPSAWS
                     FRLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLPFSEVTGSKGKADKEKVGDYVFG
                     LKAQGRYNGEPLTGTGKIGGMLALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGG
                     VDLRLKFSGDSLGDLYELTGVLLPDTPPFETDGRLVAKIDTEKSSVFDYRGFNGRIGD
                     SDIHGSLVYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSKRSEQKKGEKS
                     VQPAGKVLPYDRFETDKWDVMDADVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQP
                     LKFGMAGGSIAANIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGEMNGDAE
                     LRGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDDEVRVNC
                     AAANLNIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSP
                     LYVRGTFKNPQAGVKAGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILS
                     QMKK"
     gene            complement(11135..11902)
                     /gene="pdeH"
                     /locus_tag="ACHY1N_003342"
     CDS             complement(11135..11902)
                     /gene="pdeH"
                     /locus_tag="ACHY1N_003342"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417982.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HFS4045589.1"
                     /translation="MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRL
                     MAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLA
                     SVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
                     GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVE
                     TPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL"
     gene            12134..13063
                     /gene="kdgK"
                     /locus_tag="ACHY1N_003343"
     CDS             12134..13063
                     /gene="kdgK"
                     /locus_tag="ACHY1N_003343"
                     /EC_number="2.7.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygluconokinase"
                     /protein_id="HFS4045590.1"
                     /translation="MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
                     ALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYY
                     WRNEAAAKFWLESEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
                     GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTH
                     NAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSAENAAKRGHLTASTVIQYRGAIIPREAMPA"
     gene            complement(13159..14655)
                     /gene="yhjJ"
                     /locus_tag="ACHY1N_003344"
     CDS             complement(13159..14655)
                     /gene="yhjJ"
                     /locus_tag="ACHY1N_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFS4045591.1"
                     /translation="MQGTKIRLLAGGLLMMATAGYVQADALQPDPAWQQGTLSNGLQW
                     QVLTTPQRPSDRVEIRLLVNTGSLAESTQQSGYSHAIPRIALTQSGGLDAAQARSLWQ
                     QGIDPKRPMPPVIVSYDTTLFNLSLPNNRNDLLKEALSYLANATGKLTITPETINHAL
                     QSQDMVATWPADTKEGWWRYRLKGSTLLGHDPADPLKQPVEAEKIKDFYQKWYTPDAM
                     TLLVVGNVDARSVVDQINKTFGELKGKRETPAPVPTLSPLRAEAVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWRADLAREALFWHVQQALSASNSKDIGLGFDCRVLYLRA
                     QCAINIESPNDKLNSNLNLVARELAKVRDKGLPEEEFNALVAQKKLELQKLFAAYARA
                     DTDILMGQRMRSLQNQVVDIAPEQYQKLRQDFLNSLTVEMLNQDLRQQLSNDMALILL
                     QPKGEPEFNMKALQAAWDQIMAPSTAAAATSVATDDVHPEVTDIPPAQ"
     gene            complement(14876..16162)
                     /gene="dctA"
                     /locus_tag="ACHY1N_003345"
     CDS             complement(14876..16162)
                     /gene="dctA"
                     /locus_tag="ACHY1N_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctC"
                     /protein_id="HFS4045592.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPG
                     AGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQ
                     LGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLI
                     VLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS"
     gene            complement(16345..18333)
                     /gene="hmsP"
                     /locus_tag="ACHY1N_003346"
     CDS             complement(16345..18333)
                     /gene="hmsP"
                     /locus_tag="ACHY1N_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HFS4045593.1"
                     /translation="MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIP
                     ERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLV
                     TIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPAQELVGHQLALPRLHQDDEIG
                     MLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIIT
                     CETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHA
                     ITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGK
                     NQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQ
                     QPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQL
                     MHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDF
                     GMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPEDSSMIAAIIMLAQSLNLQMIAEGVE
                     TEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK"
     gene            complement(18415..21888)
                     /gene="bcsC"
                     /locus_tag="ACHY1N_003347"
     CDS             complement(18415..21888)
                     /gene="bcsC"
                     /locus_tag="ACHY1N_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026226.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0030244 - cellulose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose synthase complex outer membrane
                     protein BcsC"
                     /protein_id="HFS4045594.1"
                     /translation="MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHRE
                     DLVQQSLYRLELIDPNNPDVVAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSR
                     TTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIP
                     ARRGEAINQLKRINADAPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGAS
                     KIWYGQIKDMPVSDASVSALKKYLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQG
                     LAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDP
                     HSSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLG
                     DVAMARKDYPAAERYYQQTLRMDSGNTNAVRGLANIYRQQSPEKAEAFIASLSASQRR
                     SIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYRLSQDLWQA
                     GQRSQADTLMRNLAQQKPNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQE
                     LVNRLQSDQVLETANRLRESGKEAEAEAMLRQQPPSTRIDLTLADWAQQRRDYTAARA
                     AYQNVLTREPTNADAILGLTEVDIAAGDTAAARSQLAKLPATDNASLNTQRRVALAQA
                     QLGDTAAAQQTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPKQALETYKDAMVA
                     SGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGT
                     GGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDC
                     SGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISYSDDIGPLGYTVNAH
                     RRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTG
                     KNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEY
                     LSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDG
                     GSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGWQGDMDL
                     PPQPLIPYADW"
     gene            complement(21870..22976)
                     /gene="bcsZ"
                     /locus_tag="ACHY1N_003348"
     CDS             complement(21870..22976)
                     /gene="bcsZ"
                     /locus_tag="ACHY1N_003348"
                     /EC_number="3.2.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose synthase complex periplasmic
                     endoglucanase BcsZ"
                     /protein_id="HFS4045595.1"
                     /translation="MNVLRSGIVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVID
                     PSDARKITTSEGQSYGMFFALAANDRVAFDNILDWTQNNLAQGSLKERLPAWLWGKKE
                     NSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLG
                     SMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFS
                     PDWVRYEKDKGWQLKAEKTLISSYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTE
                     KNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNY
                     VLTLFGQGWDQHRFRFSTKGELLPDWGQECANSH"
     gene            complement(22983..25322)
                     /gene="bcsB"
                     /locus_tag="ACHY1N_003349"
     CDS             complement(22983..25322)
                     /gene="bcsB"
                     /locus_tag="ACHY1N_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HFS4045596.1"
                     /translation="MKRKLFWICAVAMGMSAFPSFMTQATPATQPLINAEPAVAAQTE
                     QNPQVGQVMLGVQGADAPVVAQNGPSRDVKLTFAQIAPPPGSMVLRGINPNGSIEFGM
                     RSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPIN
                     PLFITDFNRVRLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPV
                     PFFDPRDNRTNTLPMVFAGAPDVGLQQASAIVASWFGSRSGWRGQNFPVLYNQLPDRN
                     AIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAKGIAQ
                     GNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAI
                     NVSLNLPPDLYLMRSTGIDMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEAN
                     RLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMNPMPGGSVDNCITFQPVQN
                     HVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKAPNEAQMET
                     LLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIIGGIPDKLKDDKQIDLLVQAT
                     ESWVKTPMRQTPFPGIVPDESDRAAETRSTLTSSGAMAAVIGFQSPYNDQRSVIALLA
                     DSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHLPWFERLWYAL
                     ANHPILLAVLAAISVILLAWVLWRLLRIISRRRLNPDNE"
     gene            complement(25333..27951)
                     /gene="bcsA"
                     /locus_tag="ACHY1N_003350"
     CDS             complement(25333..27951)
                     /gene="bcsA"
                     /locus_tag="ACHY1N_003350"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016760 - cellulose synthase (UDP-forming)
                     activity [Evidence IEA];
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0030244 - cellulose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HFS4045597.1"
                     /translation="MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILA
                     WIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPVRYLIQTCWLLIGTSRKETPKPR
                     RRAFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGARRLILGIIVTFSL
                     ILALICVTQPFNPLAQFIFLMLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFRQFAQNVGVKYIART
                     THEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQIPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALMIALFV
                     LPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYFYGPPTEMLTVVVSMVWVFYNLIVL
                     GGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCTVQDFSDGGLGIKINGQAQIL
                     EGQKVNLLLKRGQQEYVFPTQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWAL
                     WQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRP
                     ERSETAQPSDQALAQQ"
     gene            complement(27948..28700)
                     /gene="bcsQ"
                     /locus_tag="ACHY1N_003351"
     CDS             complement(27948..28700)
                     /gene="bcsQ"
                     /locus_tag="ACHY1N_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
                     /protein_id="HFS4045598.1"
                     /translation="MAVLGLQGVRGGVGTTTITAALAWSLQMLGENVLVVDACPDNLL
                     RLSFNVDFTHRQGWARAMLDGQDWRDAGLRYTSQLDLLPFGQLSIEEQENPQHWQTRL
                     SDICSGLQQLKASGRYQWILIDLPRDASQITHQLLSLCDHSLAIVNVDANCHIRLHQQ
                     ALPDGAHILINNFRIGSQVQDDIYQLWLQSQRRLLPMLIHRDEAMAECLAAKQPVGEY
                     RSDALAAEEILTLANWCLLNYSGLKTPVGSAS"
     gene            complement(28712..28900)
                     /gene="bcsR"
                     /locus_tag="ACHY1N_003352"
     CDS             complement(28712..28900)
                     /gene="bcsR"
                     /locus_tag="ACHY1N_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsR"
                     /protein_id="HFS4045599.1"
                     /translation="MNNNEPDTLPDPAIGYIFQNDIVALKQAFSLPDIDYADISQREQ
                     LAAALKRWPLLAEFAQQK"
     gene            29173..30744
                     /gene="bcsE"
                     /locus_tag="ACHY1N_003353"
     CDS             29173..30744
                     /gene="bcsE"
                     /locus_tag="ACHY1N_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis c-di-GMP-binding protein
                     BcsE"
                     /protein_id="HFS4045600.1"
                     /translation="MRDIVDPVFSIGISSLWDELRHMPAGGVWWFNVDRHEDAISLAN
                     QTIASQAETAHVAVISMDSDPAKIFQLDDSQGPEKIKLFSMLNHEKGLYYLTRDLQCS
                     IDPHNYLFILVCANNAWQNIPAERLRSWLDKMNKWSRLNHCSLLVINPGNNNDKQFSL
                     LLEEYRSLFGLASLRFQGDQHLLDIAFWCNEKGVSARQQLSVQQQNGIWTLVQSEEAE
                     IQPRSDEKRILSNVAVLEGAPPLSEHWQLFNNNEVLFNEARTAQAATVVFSLQQNAQI
                     EPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPWNAPLSRCLTM
                     IESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGV
                     LVALRPVPGIRVEQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLP
                     TGDIFSNRMVWFEDDQISAELVQMRLLAPEQWGMPLPLTQSSKPVINAEHDGRHWRRI
                     PEPMRLLDDAVERSS"
     gene            30741..30932
                     /gene="bcsF"
                     /locus_tag="ACHY1N_003354"
     CDS             30741..30932
                     /gene="bcsF"
                     /locus_tag="ACHY1N_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0052324 - plant-type cell wall cellulose
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HFS4045601.1"
                     /translation="MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPR
                     YVKPAGTLRRTEKARATKK"
     gene            30929..32608
                     /gene="bcsG"
                     /locus_tag="ACHY1N_003355"
     CDS             30929..32608
                     /gene="bcsG"
                     /locus_tag="ACHY1N_003355"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0030244 - cellulose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="HFS4045602.1"
                     /translation="MTQFTQNTAMPSSLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHP
                     LLNLVFAAFLLMPIPRYSLHRLRHWIALPIGFALFWHDTWLPGPESIMSQGSQVAGFS
                     TDYLIDLVTRFINWQMIGAIFVLLVAWLFLSQWIRITVFVVAILLWLNVLTLAGPSFS
                     LWPAGQPTTTVTTTGGNAAATVAATGGAPVVGDMPAQTAPPTTANLNAWLNNFYNAEA
                     KRKSTFPSSLPADAQPFELLVINICSLSWSDIEAAGLMSHPLWSHFDIEFKNFNSATS
                     YSGPAAIRLLRASCGQTSHTNLYQPANNDCYLFDNLSKLGFTQHLMMGHNGQFGGFLK
                     EVRENGGMQTELMDQTNLPVILLGFDGSPVYDDTAVLNRWLDVTEKDKNSRSATFYNT
                     LPLHDGNHYPGVSKTADYKARAQKFFDELDAFFTELEKSGRKVMVVVVPEHGGALKGD
                     RMQVSGLRDIPSPSITDVPVGVKFFGMKAPHQGAPIVIDQPSSFLAISDLVVRVLDGK
                     IFTEDNVDWKKLTSGLPQTAPVSENSNAVVIQYQDKPYVRLNGGDWVPYPQ"
     gene            complement(32695..32802)
                     /gene="ldrD"
                     /locus_tag="ACHY1N_003356"
     CDS             complement(32695..32802)
                     /gene="ldrD"
                     /locus_tag="ACHY1N_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HFS4045603.1"
                     /translation="MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK"
     gene            complement(33178..33285)
                     /locus_tag="ACHY1N_003357"
     CDS             complement(33178..33285)
                     /locus_tag="ACHY1N_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HFS4045604.1"
                     /translation="MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK"
BASE COUNT         7856 a         9116 c         8369 g         7956 t
ORIGIN      
        1 ttgatcgaca aatccatcaa tttatggacg ttttcgtcgt cccaggtctg gcagaaagtg
       61 gccaggttct gacgagcgtt gccatcaaga tataattcat cattgataat ctggaatgcg
      121 acatcatcgc gcatttcgtg cagcggaaat cgttttgact ccgcgatagt agaaatggcc
      181 tttgcgccaa aacgtgaatc gagtagttct gagcggaaat ccgttaacag cttctggtcc
      241 atttcgaact ccttaaattt atttgaaggc aataaaaaag taggatttat ccgcaatgga
      301 agcaaggcat tacaggctta atttaaataa caaaatccta agcagaaaaa cgacttttta
      361 taatataaac atttaacatg ataatattaa aaacagactt tattatcgta ataaaaatcg
      421 cccaaacatt cctgttcggg cgatcaaatt aattattgtt tatcctgcat atacggcgtg
      481 tacaccccgt tcagactgtg caggaaagct acgatatcat ccacatcctc ctgcggcagc
      541 tctttgccta cctgatagcg cagcatcagt ttcaccgccc cgtccagcgt cggcacgtca
      601 ccgcgatgga agtacggtgc cgttaaagca acgttacgta aaccgggtac tttctgacgc
      661 aatttatcac gctcttcttt agtcacattc atacgaccaa tatccgccgc cgtaatttcc
      721 ccaaagttaa agtctttttt cagccccaac ggttcaaagg aacgtccgcc gagaataata
      781 ccaccatgac aagttgcaca tttattatct ttaaataatt gatagccttt tttctgttgc
      841 gccgtcagcg cattttcatc tccacgcaac catttatcaa atggggaatc cggcgtaatt
      901 aatgttttct caaattcagc aatggcatca gtaatatttt cgccactgaa accttgcgga
      961 taaacttcga ggaactgcgc tttaagctgc ggatcttttt ccagcttagc aataatttcg
     1021 tcccaggatt tcgacgccat ttcaatcggg ttcaacggcg gtccacctgc ctgatcctgc
     1081 aatgttgccg cacgaccatc ccagaactgc tcaacgttaa atactgagtt aaataccgtc
     1141 ggcgcgttaa tcggcccaac tgcgccacca acaccaatcg atgtttttct gccatcgacg
     1201 ccccccgcat tcaacgcatg gcaatgagcg catgaaatgg tgctatcagc cgataaacgg
     1261 ggatcgtgat acagcgcaaa gcccaacgcc actttttgcg catcggtagg cagtttttgc
     1321 gggatgggct gcaccggttc attgcgatgc tccggagcag tatcattgct ggcgtaatat
     1381 tctgcgcgct gttttgcaat ccaggccagt atttccgccc gctcttcatc actcacctta
     1441 cccgcccagt gtagcgcggt ataacgcgtt ggtggcatag tttcatactg catcacccat
     1501 tcaatcttat tcagatcgct ttgcgaaacg ggtttatcag ccagcagtgc cgcacgcacg
     1561 gcctcgaggt taaaagattt atatccaagc ttaatgtcgt aatccatcaa ctgtttcgcg
     1621 ccaggaatat aataataggc gggtaattct gccgaaggtg tgtggcaata gtcgcatcct
     1681 ttttcgcgga gaaagcctaa aaccttatta ttttcactga cagcagatgc ctgaacatcg
     1741 gcctgtttac tgcgtttatt atcgtggtac cacacataac cagataaccc taaatagcaa
     1801 atcgcgacgc cagccaggcc gatcgcggta atacgtgaga ccattttcat tattcttccc
     1861 tcacggtggt gagttattgt gacccagaaa attttccaga atgctgcaaa cgtctctgcg
     1921 agacaaagcc atcataaaaa acagggagat acgctttttg ataggaatca atcaattaca
     1981 tgaatataaa ctatcaataa gatagcctgt gcctattacc cagatcagga atggcatatc
     2041 atgattgcgg cgagagcagg attgaatgtt ctgaaaatga aaaacaacac gaaatccgta
     2101 tttttataaa ttccatggat attagtgcgt tatatttttt gacaggttaa taaacgtgat
     2161 ccaccgcacg ctttgtcgcc caccaggcgg agcgaatgac tacccttaaa gaaaagcccg
     2221 ataattagcg acgaatttcg gaggttggat ccttatgctc aatcagaaaa ttcaaaaccc
     2281 taatccagac gaactgatga tcgaagtcga tctctgctat gagctggacc cgtatgaatt
     2341 aaaactggat gagatgatcg aggcagaacc ggaacccgag atgattgaag ggctgcccgc
     2401 ctctgatgcg ctgacgcctg ccgatcgcta tctcgaactg ttcgagcatg ttcagtcggc
     2461 gaaaattttc cccgacagta aaacctttcc cgactgcgca cccaaaatgg acccgctgga
     2521 tattttaatc cgctaccgta aagtgcgccg tcatcgtgat tttgacttgc gcaagtttgt
     2581 tgaaaatcac ttctggctgc cggaggtcta ctccagcgag tatgtatcgg acccgcaaaa
     2641 ttccctgaaa gagcatatcg accagctgtg gccggtgcta acccgcgaac cacaggatca
     2701 cattccgtgg tcttctctgc tggcgctacc gcagtcatat attgtcccgg gcggccgttt
     2761 tagcgaaacc tactattggg attcctattt caccatgctg gggctggcgg aaagtggtcg
     2821 ggaagatttg ctgaaatgca tggccgataa cttcgcctgg atgatcgaaa actatggtca
     2881 catccccaac ggcaaccgca cctattattt gagccgatcg caaccaccgg tttttgcgct
     2941 gatggtggag ttgtttgaag aagatggtgt acgcggtgcg cgccgctatc tcgaccacct
     3001 taaaatggaa tatgccttct ggatggacgg tgcagaatcg ttgatcccta atcaggccta
     3061 tcgccatgtt gtgcggatgc cggacggatc gctgctcaac cgttattggg acgatcgcga
     3121 cacgccgcgt gacgaatcct ggcttgagga cgttgaaacc gcgaaacatt ctggtcgccc
     3181 gcccaacgag gtgtaccgcg atttacgcgc gggagcggcc tcaggttggg attactcttc
     3241 ccgttggctg cgtgatactg gtcgtctggc gagcattcgt accacccagt tcatccccat
     3301 cgatctgaat gccttcctgt ttaaactgga gagcgccatc gccaacatct cggcgctgaa
     3361 aggcgagaaa gagacagaag cgctgttccg ccagaaggcc agtgcccgtc gcgatgcggt
     3421 aaaccgttac ctctgggatg atgaaaacgg catctaccgc gattacgact ggcgacgcga
     3481 acaactggcg ctgttttccg ctgccgccat tgtgccgctc tatgtcggca tggcgaacca
     3541 tgaacaggcc gatcgtctgg caaacgccgt acgcagccgg ttactgacac ctggcgggat
     3601 tctggcaagc gagtacgaaa ccggtgaaca gtgggataaa cccaatggct gggcaccgtt
     3661 acaatggatg gcaattcagg gatttaaaat gtatggcgat gaccttctgg gtgatgaaat
     3721 cgcgcgcagc tggctgaaaa cggtgaatca gttctatctg gaacagcaca aaatgatcga
     3781 gaaataccat attgccgatg gtgttccccg cgaaggcggc ggtggcgagt atccgttgca
     3841 ggatgggttt ggctggacta acggtgtggt acgccgttta attggtttgt acggcgaacc
     3901 ataatatttt tacagccagc cgctaacttc ctgctggctg taaaattatc ctcttcagga
     3961 ggagatattt aacatcattg ccgcctgggt gcgatttttc acttccagac ggcgatacag
     4021 ggattccaga tgcgctttta ccgttccggt actgatattc agcgctctgc tgatctcctt
     4081 atttgattcg cccgccgcta acatggttaa aatctcccgc tggcgggcgc ttaacgattt
     4141 gagatcttta atgtcctttt ccggcgtcgt ccgccagtct ccaggcagaa acatcatccc
     4201 catcgccgca ctatttaccg ccaacgcaaa tgtctcgacg gttgaatcac gaggcacaat
     4261 ggccagcaca ttaaaatgaa taacttcctg taaccaccgt ttattgcaat ccgtcgccgt
     4321 gattaacacc ttaacctcag gaaactgcac cacggttttt tgcagcaacc agtagcaaaa
     4381 ctcaccatcc tgatcgccat cgagcataac taaggcttca gggtaacttt ccagcttttg
     4441 ccataactcg tctgcctgac tggccccctg aatactcact cctggaatac gctgctgtaa
     4501 actgattttc attccatgaa taaatattga ctgcctgtca aacatgacta tttgcataac
     4561 tgaatctcca cctgaatacg ttaaaaagac ttaagtagtg gaagggtatt acccgcgaga
     4621 aaaaataaga attcgccatt tggcggtggc cattctacag agatgacgcg tagaaaatag
     4681 ttaccgatat aaatagttac agctaaacgc ctgaaattac atgtcgaggg cactatttaa
     4741 aacaattttg aggatttcct tatattggtg gttagtacgc atgcaattaa aaatgaaact
     4801 ccgcgaccac aagcaaaaat aacaaacggc aatgagacaa aaataagcac aaatagccaa
     4861 cacgtcctct attcacttta aagggaatcg ctgaaaaata cgctctgttt agggggattc
     4921 acctttctca gaaagctatt ccgccctttt cctgctgaga aatcgccaca ttcgtcatga
     4981 caacattgtg aaacccggca ttagatgtta gaaaaaacaa taaacaatgc gatatgcgcg
     5041 ttactgtttc gctgtgaaca acaatcggtc aaagaaatgg ataaaattca cgcaatgcag
     5101 ttgttcatca aagtcgcgga gctggaaagt ttttcccgcg cggcggattt ctttgctttg
     5161 ccaaaaggaa gtgtttcgcg ccagatacag gcactggaac atcaacttgg cacccagctt
     5221 ctccagcgca ccacgcgacg ggtcaaactc acgccagaag gcatgaccta ttatcaacga
     5281 gcaaaagatg tgttgagtaa tctcagcgaa ctggacggtc tgtttcaaca ggatgccacc
     5341 agtatcagcg gtaaattacg catcgacatc ccgccaggaa tcgcgaaaag cctgttactg
     5401 ccgcgcctgt cggaatttct ctatctgcat ccgggaattg agctggaact gagtagccat
     5461 gaccgtccgg tagatattct tcatgatggt tttgattgcg tgatacgcac tggcgcgtta
     5521 ccggaagatg gcgttatcgc ccgtcccctc ggcaaactga ccatggtcaa ctgtgccagt
     5581 ccgcactatc tgacgcgctt tggttatccg caaagccccg atgatctgac ttcacacgca
     5641 atagtgcgtt atacaccgca cctgggtgta catccgttag gttttgaggt tgccagcgtt
     5701 aatggcgtcc agtggtttaa gtctggcggc atgttgacgg taaacagtag cgaaaactat
     5761 ctcgccgccg gtcttgccgg tctggggatt attcagatcc cgcgcattgc cgtgcgcgaa
     5821 gccctgcgtg ccgggcggct tattgaagtg ttgccaggct accgtgccga gccgctctcc
     5881 ctttcgctgg tttacccgca gcgtcgggag ctttcccggc gtgtaaacct gtttatgcag
     5941 tggctggctg gcgtaatgaa agagcacctg gactgaccga ctatactttt taagaatgac
     6001 cacgacagaa ggacaaaaga gcggatgacg caggaaaacg agatcaaacg tcccacccag
     6061 gatctggagc acgagccgat taagcagttg gataatagcg agaaaggcgg caaagttagc
     6121 caggcgctgg aaaccgtcac caccactgcc gaaaaagtcc aacgccaacc ggttattgcg
     6181 cacctgattc gcgcgacaga acgctttaac gatcggctgg gtaaccagtt tggtgcggct
     6241 atcacctatt tctcattttt atcgatgatc ccgattttga tggtgtcgtt tgccgcaggg
     6301 ggctttgtgc tggcctccca tccgatgttg ctacaggata tcttcgacaa aattctgcaa
     6361 aacatcagcg atccgacgct agccgccacg ttgaaaaaca ccatcaacac cgccgttcag
     6421 cagcgtacga ctgtagggct tgtcggcctg gcggtggcgc tttattctgg catcaactgg
     6481 atgggtaacc tgcgtgaagc gattcgtgcc cagtcgcgcg atgtctggga acgctcgccg
     6541 caagatcagg agaagttctg ggtaaaatat ctgcgtgatt ttatttcact gattggtttg
     6601 ttaattgcgc tgattgtgac gctgtcgatc acctcggttg ccggttcggc gcagcaaatg
     6661 attattagcg ccctgcacct gaacagcatt gagtggctga aaccgacgtg gcggttgatt
     6721 ggcctggcga tttccatctt cgccaactat ctgcttttct tctggatctt ctggcggttg
     6781 ccgcgccacc gtccgcgcaa aaaagccctg attcgcggaa catttctggc tgctattggt
     6841 tttgaagtga ttaaaatcgt gatgacctac accttgccat cgctgatgaa atccccctct
     6901 ggcgcagcat ttggttccgt gctggggctg atggcatttt tctacttctt cgcccgtttg
     6961 acgctgtttt gcgcggcgtg gattgccacc gccgaatata aagacgaccc gcgaatgcca
     7021 gggaaaacgc agccttaaaa taggccggat gcggcgtaaa cgccttatcc ggcatacgat
     7081 tttattcggc ctggctcccc gtaggccgga taagatgcgc cagcatcgca tccggctata
     7141 atgcgcacat aacctcttga aactcttccc cagagcctct tcagccatct atttgggagc
     7201 aaacaatttc attccaactc ataaccccag catataaatc cagttggtaa cttttattta
     7261 acctgaaacc agttttatcc actatttata aaattatgtg aagcatttca tagaagaaaa
     7321 atcactggcc taaacattat cccctttttg cctggttttt gaccatttcc gcgatttgtt
     7381 acacattgaa atatcacttt tgctgtgcgt aatatggcta ttcgttagcc aaaaaataag
     7441 aaaagattat gcaagcaaca gccacaacac tcgaccacga gcaagaatac acgccgatca
     7501 actcgcgtaa taaagtcctt gtcgcctctc tcattggcac ggccattgag ttcttcgact
     7561 tttacattta cgccactgcg gccgttattg tgtttccgca tatcttcttc ccgcagggcg
     7621 atccaacggc agcaacgcta cagtcgctcg ccaccttcgc catcgccttc gtcgcgcgcc
     7681 ccattggctc tgccgttttt ggtcattttg gcgatcgcgt tgggcgtaaa gcgacgctgg
     7741 tcgcctcgtt gctaacgatg gggatttcga ccgtggtgat tggtctgctg ccgggctatg
     7801 ccacgattgg tattttcgcc ccgctgctgc tggcgctggc tcgatttggt cagggtctgg
     7861 gcttaggcgg tgaatggggc ggcgcggcgc tgctggcgac tgaaaacgcc ccaccgcgca
     7921 aacgtgcact gtatggctcc ttcccacagc tgggcgcacc gattggcttc ttctttgcca
     7981 acggcacttt cttgctgctt tcctggctac tgaccgacga gcagtttatg agctggggct
     8041 ggcgtgtgcc atttatcttc tcggcggtgc tggtcattat cggcctgtat gttcgcgtgt
     8101 cgctgcatga gtcgccggtg tttgagaaag tcgctaaagc gaaaaaacag gtgaagatcc
     8161 cgctgggtac gctgctgacc aaacatgttc gcgtaaccgt actgggtacg ttcattatgc
     8221 tggcaaccta tacgctgttt tacatcatga cggtctactc tatgaccttt agtaccgccg
     8281 ccgcgccagt tgggcttggc ctgccgcgta acgaagtgtt gtggatgctg atgatggcag
     8341 ttattggttt tggcgtgatg gtgccagtcg ccggattact ggcagatgcc tttggtcgcc
     8401 gtaaaagtat ggtaattatc accacgctga tcatcctgtt cgcgctgttc gcctttaacc
     8461 cgctgcttgg ttctggcaac ccgattctgg tttttgcctt cctgctgctg gggttaagtc
     8521 tgatggggct gaccttcggg ccgatgggcg cgctgttacc agagctgttc ccaacagaag
     8581 tgcgttacac cggagcatcg ttctcttaca acgtagcgtc gattctcggg gcttccgttg
     8641 caccatatat cgcagcctgg ttgcaggcta actacgggtt aggtgcggtg gggttatatc
     8701 tggcggcgat ggctggcttg acgttaatcg ccctgctgct gacccatgag acgcgacatc
     8761 agtcgttgta agtatcgtgt gggcagccac cctcacccca gccctctccc tgaaagggag
     8821 agggagaaaa gcggagcgag atgttatatc gcgaacataa cagccctccc ccagaaagtg
     8881 aacggaaaag cggtactcgt tgtttcaaca cgcacaaaac agtcccctcg cccctttggg
     8941 gagagggtta gggtgagggg aacacgctgc tcccgaactc accagcaaac acaatccaac
     9001 ctcatcactt cttcatctgc gacaatatcg tccgacactg attagcctcc ccttcggaag
     9061 gtgagatcag tgccagtaac gccgccgccg gtgttaccag cgttgccagt gccgcagcaa
     9121 cagcaccacg ggcaatcaac ggcccggctt tcaccccagc ctgcggattt ttaaacgtcc
     9181 cacgcacata cagcggcgaa cgcagtgtga taatccgaat ccctttactc tccggatcaa
     9241 tagtcaaatc cagctgttcc gaagcaaaac ttgccgtgcc ggtaacatta atcaacgcgt
     9301 tctcagtatc gaaagcaaaa atctgcgggc gcgccacgcc gttggcaata ttcagattcg
     9361 ccgccgcgca gttcacccgc acctcatcgt caccaaatat cgcaccgaca atgtagttgc
     9421 cgacattcag cccaacaatc tccatcaggt tgcggctcac cagcccgtca ttcatcaaca
     9481 gtttcaggtt gccgttactg ttgcctaaaa gtgctgccac cgagttaccg ctaccgcgta
     9541 gttccgcgtc accgttcatt tcccccagcg tcttctgcat cagttccaca tcgggcatca
     9601 gttctttcag tttcagtcga cgagcctgaa tatctgcccg cccctgcatc ggctttttat
     9661 cgccttccag atgaatattc gccgcaatgc tgccgcccgc catgccaaat ttcagcggtt
     9721 gcaggcgcag gtcagcattt ttgaggatga tatgagtaga aagatcgcta atcggcaggc
     9781 tactgccatg ctcaatgcgc cgccctttga agcgaacatc ggcatccata acgtcccatt
     9841 tatcggtttc gaagcggtca taaggcagca ctttgcccgc aggctgaacg cttttttcgc
     9901 ccttcttctg ttcagaccgt ttcgactttt ctgccccttt cccggagtca acgccaatta
     9961 acggtcccag gtccgccagc cgcaattgcc gcgactcgac atcaccttcc agttttggtc
    10021 gtggctttcc ggtggtgtag accagagaac cgtggatatc gctatcgcca attcgcccat
    10081 taaaaccgcg ataatcaaag accgacgatt tttcagtgtc gattttcgct accagccgac
    10141 catccgtttc aaacggcggg gtatcgggca gcagaacgcc cgtcagttca tagagatcac
    10201 ccagtgaatc gccagaaaat ttaagccgta aatcgacacc gcccatcttc attgggtcat
    10261 tcacgacgcc atcaaaagca acacgggtgt taccagagcg gaaatcagcc tgtaccggaa
    10321 acggcgtccc ttcgccacgc agcgccagca taccgcctat ttttcccgta cccgtgagcg
    10381 gttcaccgtt ataacgtccc tgcgccttca ggccaaaaac gtaatcgccc accttttctt
    10441 tatccgcttt acctttcgat ccagtaactt cgctgaacgg cagcggcttg cctaacggat
    10501 caacaaaaat ctccagatcc gctttgctta ctttgtcatc aatagcgatc cgcccttgat
    10561 cgaaaagaat attatccagc cgaaacgacc atgccgacgg ctttgcattc gcgtctttgt
    10621 tatcatcgtt ggcgagatta aacgtccagt tattgttctt ttcggagagg cgaatcaggc
    10681 gcgcgtcggg cttttcgagc ttgatccacg gcagccagac cgttttggtc agcagcgcca
    10741 gcggggccag cgttgcctct acgcgtggca aatgcaccat cgtgacttcg ggaatatccg
    10801 gtggattgcc aagaatgatg tcttccgcgt gtacatgggg ccacggcacc cagctgcgcc
    10861 agccagtttc ttgtttttgc cgctcccaca ccacgcccag atcgccacgg atagcgaacg
    10921 gacgattcaa ctccgcagag actttctggt tgatggtcgg tttgagtcga ttccagtcaa
    10981 aagttgcaat caaaatgatc gccacgacaa tcaacaacaa gaaagcccct gaaatcgcag
    11041 cggttatttt gcctgccttg ctcatcgttc gcttcctcat attcttcctg tgccagtcct
    11101 aaagatagtc cagccaggcg gaaaatgagg cagcttatag cgccagaacc gccgtattca
    11161 gcgtttctat cggtgccggg cgtgaaagaa accagccttg tgcggcgaat gcgggcgagt
    11221 tctgaacatc acgccactct tccggtgttt ctacgccctc gacaatcacc ccgcgacaat
    11281 agcgattcat tagatgtaaa agctgagaaa agagtgtgcg gccttccggc gactgacgca
    11341 gcatcacgaa cagctctcgc gcgattttga tgtagtcata acgcacttca cttagcgcag
    11401 agaaatttgc catcccggtg ccaaaatcat ccagccacag cgggccaaat tcacacatcg
    11461 aggcaaaggt tgaatctttc ggcagacgga tatgctccac cagttcgaaa cgcagccagg
    11521 gaagacgctc aatctggcgc aggatttttg gttgctgacg cagggcgatg agcgtagggc
    11581 catcaatatt gaccgatgcc agcaggccgt gctctataaa gaagtcggct ttttgcgcca
    11641 gcaaatcaat ctgctctttc acaacctcca tccgatggct gacggtgatt tcagtaaaat
    11701 agcgatccgg cggcaggcgt tgcgaagggt tcaagggatg cgtgaccacc gttaatagct
    11761 ccacggccat taaccgtccg catgtttgat agatcggctg ccaggtgtaa gcacgctcac
    11821 actgcaacca aaaacgccgt tcctgcaagc tctcgatgct tgcttcaggg ttgcttattc
    11881 gctggataac ctgccttatc atcaaagatg tcctgtgttt aaaagtgatg ctgcccggac
    11941 tcgacaaaga ttatcggcgc gcaagggcag aactttaccg cctggccggg gtaaatttcc
    12001 tcactccaca acggaatctt tcaggaatac gttctggctc aaaaaaataa tggaacactg
    12061 ttttaatatg gttgaccagc aaaccaccac agcgcaaact aacgctaatt ttttacagat
    12121 caggttcacg actatgtcca aaaagattgc cgtgattggc gaatgcatga ttgagctttc
    12181 cgagaaaggc gcggacgtta agcgcggttt cggcggcgat accctgaaca cttccgtcta
    12241 tatcgcccgt caggtcgatc ctgcggcatt aaccgttcat tacgtaacgg cgctgggaac
    12301 ggacagtttt agccagcaaa tgctggacgc ctggcacggc gagaacgttg atacttccct
    12361 gacccaacgg atggaaaacc gtctgccggg cctttactac attgaaaccg acagcaccgg
    12421 cgagcgtacg ttctactact ggcggaacga agccgccgcc aaattctggc tggagagtga
    12481 gcagtctgcg gcgatttgcg aagagctggc gaatttcgat tatctctacc tgagcgggat
    12541 tagcctggcg atcttaagcc cgaccagccg cgaaaagctg ctttccctgc tgcgcgaatg
    12601 ccgcgccaac ggcggaaaag tgattttcga caataactat cgtccgcgcc tgtgggccag
    12661 caaagaagag acacagcagg tgtaccaaca aatgctggaa tgcacggata tcgccttcct
    12721 gacgctggac gatgaagacg cgctgtgggg tcaacagccg gtggaagacg tcattgcgcg
    12781 cacccataac gcgggcgtga aagaagtggt ggtgaaacgc ggggcggatt cttgcctggt
    12841 gtccattgct ggcgaagggt tagtggatgt tccggcggtg aaactgccga aagaaaaagt
    12901 gatcgatacc accgcagctg gcgactcttt cagcgccggt tatctggcgg tacgtttgac
    12961 gggcggcagt gcggaaaacg cggcgaaacg cgggcacctg accgcaagta ccgttattca
    13021 gtatcgcggc gcgattatcc cgcgtgaggc gatgccagcg taaacgcagc atatgcaaaa
    13081 ggctggataa agtgttactc ctctatccag ctcatccata aatacctgat ggttgtgcta
    13141 actcatcacc atcaggcatt actgtgcagg tggaatatcc gtcacttcag gatgtacgtc
    13201 atccgtggcg acagaggtgg cggcagcagc agtcgatggg gccatgattt gatcccaggc
    13261 cgcctgcaac gctttcatgt taaattccgg ctcgcctttc ggctgcagca gtattaacgc
    13321 catatcattc gacaactgct gacgcagatc ctgatttaac atctccaccg tcaggctgtt
    13381 aaggaaatcc tgccgcagtt tctgatactg ctccggcgcg atatcgacga cctgattttg
    13441 caacgaacgc atccgctgac ccatcagaat atcggtatca gcccgcgcat aggcggcaaa
    13501 cagtttctgc agctccagtt tcttttgcgc cactaacgca ttgaactctt cttccggcag
    13561 acctttatcg cgaaccttcg ccagttcacg cgccaccaga ttaaggttgc tgttcagctt
    13621 gtcgtttggt gattcgatgt tgatggcaca ctgcgcacgc agatacagca cacggcagtc
    13681 aaatccaaga ccgatgtctt tgctgttact ggcgcttaac gcttgctgaa catgccagaa
    13741 cagcgcctcg cgggccaggt ccgcacgcca gtagcgcagc agtgcggctg attcacgaat
    13801 cggctgccac ggcgtatccc acatgataga taaccggtcc tgacgcaccg cgtcagtcat
    13861 aatactcacc gcttccgcac gcagcggaga aagcgtcggc accggagctg gcgtttcacg
    13921 tttgcctttc agttcgccaa acgttttgtt tatttggtcg acaaccgagc gcgcatccac
    13981 gtttcccacc accagtagcg tcattgcatc cggggtgtac catttctgat agaaatcttt
    14041 aattttttcc gcttcaacgg gttgtttcag cggatcggca ggatcgtgac ctaacaaggt
    14101 tgaccctttc agacgatagc gccaccagcc ctctttagta tcggcaggcc aggttgccac
    14161 catgtcctga ctttgcagcg cgtggttgat ggtttctggt gtgatggtca atttgccagt
    14221 ggcatttgcc agataagaga gcgcttcttt cagcaaatcg ttacggttat tgggcaaact
    14281 cagattaaac agcgtggtgt cataagagac aattaccggc ggcatcgggc gtttagggtc
    14341 gatcccctgc tgccacaatg aacgcgcctg tgctgcgtca aggccaccgc tttgcgttag
    14401 cgcaatacga gggatggcgt gactgtaacc gctctgttgt gtactttcgg cgagcgaacc
    14461 ggtattaacc agcaggcgaa tttcaacacg atcgctggga cgctgggggg tggtcagcac
    14521 ttgccactgt aaaccgttgg aaagcgtccc ctgttgccat gctggatcag gctggagcgc
    14581 atctgcctgc acatagccag cagtggccat catcagcaaa ccgcccgcta aaagtcgaat
    14641 ttttgtgccc tgcatgtgaa cccctgatca actatcctgg taataaaaaa actgcccgtt
    14701 gtcggtcagt ctaaatgacg ttaaaaacac ttcgtgttag accgcaagaa catgaaaatg
    14761 tcacggaaga agtgaaataa acctgaactc acccaggtgg taagttcagg cacaggggtc
    14821 aattatgcgc aaacacccgc actcggggaa gggagtgcgg gcataagtga tgagattaag
    14881 aggataattc gtgcgttttg ccatccggcg cacgattatt cagcacatcg tccagttttt
    14941 tgtggtccag ttctttcacc cacttagcaa cgacaatggt cgctacgccg ttaccgacca
    15001 ggttagtcag cgcacgagct tctgacataa agcggtcgat accgaggatc agcgccagac
    15061 ccgctaccgg caaatggccc accgcagaga gcgtcgccgc cagcacgata aagccactac
    15121 ccgttacccc tgccgcccct ttagaagaaa gcagcaacac gattaacagc gtgatttggt
    15181 ggacgatatc catctgactg ttagtggcct gggcgataaa caccgccgcc attgtcaggt
    15241 atatcgatgt gccatcaagg ttaaacgagt agcctgtcgg gatgaccagc cccaccaccg
    15301 atttgcggca gccgagtttc tccatcttgt cgagcatacg cggcagcgcc gactcggaag
    15361 atgaagtccc cagtacaatc agcagttctt cacggatgta gcggataaat ttgaagatac
    15421 tgaaaccagt cgctttagcg attgaaccca ataccagcac cacaaacagg atacaggtaa
    15481 tgtagaaaca gataatcagc tgccccagtt gcaccagtgt gccgacgccg tatttaccga
    15541 tggtaaacgc cattgccccg aacgcaccaa taggcgccag acgcatgatc atattgatga
    15601 tgccgaagat gacctgcgag aaactttcga tgacgttaaa aatcagttgg cctttgctgc
    15661 ccagacggtg gagcgcaaaa ccaaacagta cggcaaacag cagcacctgc agaatgttac
    15721 cgctggcaaa tgcgccaatg acgctcgccg ggatgacatc cataatgaag gcgacaatgc
    15781 cctggtcttt cgcctgatcg gcgtaaaccg ctaccgcttt cgcatcaagc gttgccggat
    15841 cgacgttcat tccggcacca ggctgcacga cgttaacgat gataagacca ataatcagcg
    15901 cgatggtact gacaatttca aagtaaagca gtgcgactgc gccggtacga ccgaccgcct
    15961 tcatgctttc catgcccgca atgcccgtta cgacggtaca aaagatgaca ggagcgatga
    16021 tcatcttaat gagcttaacg aagccgtcgc caagcggttt catttgctcg cctatttcag
    16081 gatagaaatg gccaaggaga ataccaatgg ctatcgctgt caggacctga aagtaaaggc
    16141 ttttaaacag agaggttttc atagggtgtc ctttagtaaa accacaggtc ttgtaaggtt
    16201 atggggtacc tgcggcctta aaataacacc cagacaacat cacagaaatg tacctggatc
    16261 ataattgaaa caaaaaggtt aaaaagtttg agctggctcg cacaaaccag cactttttaa
    16321 agttttgtaa tcagtttggg gtagctactt ttcttccagg taactctctt cgaagatttc
    16381 aatagggagt gggcgagcaa aaaggaagcc ctgggcaata ccaacgcccg cttttgccag
    16441 ccagtcgcgt tgtgcttcag tctccacgcc ttcggcaatc atttgtaagt tcaggctctg
    16501 cgccagcatg ataattgcag caatcatgct gctatcttcc ggcaagcctt caacaaacat
    16561 tttgtcgatt ttcagtacgt cgattggcaa cgatttcata tgctgcagct gacgcagccc
    16621 tgcgtagccc atgccgaaat catccagcgc cacccgaact ccggcattgc gcagcggacg
    16681 gaggattgcc accgcagcat gagggtcgtc aatacgtcgg ctttctgtca cttccagaat
    16741 cagtgttccc ggctgaatgc gatagcgggt taacagttcc agcatatccg ccaccatatt
    16801 cgggtgcatc agttgcagcg cagagaggtt taccgacaag ggcagcataa tgccgcgctc
    16861 ttgccaggct gcaagcaatc gacaggactc ttccagcacc cagtgaccga cggtaaccat
    16921 gagcccacag cactcaatgc gatcgattaa gccatccggc aggtcccaac tgccatccgg
    16981 ttgctggata cgcagtaaca cttccgcact gaccagttta ccgctggtca tctcgacctg
    17041 tggctgtaac caaattgcaa actgatgatt ttccagtgca ttaaggatat cgctctcttc
    17101 cgtcaaccgc ttctgggcgg cttccatctg ctgcggatca aagaactgaa tctgattctt
    17161 gcctttatgg cgagcggtaa atgccgcaga aatagcgcga ctgtaaagct gttcggcggt
    17221 gagatcgccg tagaacatcg ccacgccaat gctacagtgc ggacggagtt gaatacgttc
    17281 aatcggcagg cgctcgctca tgatagtgag cacttgctga cctaaggtga ttgcgtgcca
    17341 cggttcctgt acaccgttgg caatgacagc aaagtcataa ccgctaatct gcgcgaggat
    17401 catacgtggc gacagtaccg atttgagttt ttccaccagc gtcagcagca gaatttctcg
    17461 ttgcgcctct ttcagcacgc ccgcagtatc acgcagggtt tcacaggtga tgatcatcag
    17521 cgcggtggtt tgtttacgcg cgacaacctg ctccagcatc tccatcagca aggctttgtt
    17581 cggcaaatcc gacaccggga agcgcatcgc attttcgttc tgttcttcat aatggcgctg
    17641 cagcaattgc tggttgaggt tgtaactgcg caccaacata ccgatttcat cgtcctgatg
    17701 cagacgcggt aatgccagtt ggtgaccaac aagctcctgg gctgggatgg cgttaagttc
    17761 gcgagcaata ttgcgtaacg gatgcaaaat caggcggtta atgcaccagc tgatggcgac
    17821 ggtcaggata agcgacaaaa gtaagtaaat ggtcactaac gttgagaggg tgctcatcac
    17881 gaacttatac atacggaagg aatccgcctg tagtaccaga taggcaattg gctgcgggtt
    17941 tgccggacgt tcgagcgagt aaacgcccag cgagatttga accggtagct caaacaggcg
    18001 agtaaccatt accggcaccg ggcgctctgg aataaaactt ttacgcagcg cctggaactg
    18061 gttaggcagc actacatcgg cacggctgac cacgcctgcc ggtttaatgc tggcaagaat
    18121 agcttccgct tcgggaatat cgcctttcaa aatagctgaa gataagggtt cgcggacaga
    18181 gcgagcaatg ctttccagtt gcgtagccgt gttatagcga ttctgttgga ccagatggaa
    18241 cagcaaaacg gtgcaaaaaa taaaaacgaa caccaggaca acggctgcca ccattgccat
    18301 ctgcttgatt gttaacgagc gacttacgcg caaattgtct ccccccggaa atcccagatt
    18361 gccgcccgag tatacccgat cgcagcggca ttaagagagg cgctatctga aaacttacca
    18421 gtcggcgtaa ggtatcagcg gctgcggcgg taaatccatg tcaccctgcc atccggcggc
    18481 ggaataacgt acgtagagca ggaaatggct gggtgcgtaa tctttcgcct gctggatatc
    18541 aattgccgtg ccaacaaacc agttggaagt aacacgtcgt tcaagtaatg cccgcgccgt
    18601 gtagccgaag ccctgactgc tgccgccatc gttggattgc cgcgcagctt cttcctgcca
    18661 gtcggtcggg atcagattca tcagcggata acgcggcatg gttttggtgc gtgaatgcga
    18721 ccacgagcca gacgccccca gctcccacga ccagttttcc gtgcgctccc gccacatcac
    18781 cggtatggca aacgacaggt attcctgcgg actgtagtaa ccgccctgac cgagtgagta
    18841 gccactcaga tctttgtcgt aatgccagat catgttgttc aggccgattg tgacgcggcg
    18901 attgttctgg ttaatgacct tatagtaata gcccgtcatc cagcgcacgc gccagttatc
    18961 ttcgacattt ttaccggtta actggtcgcc actaagcgat gcccagacgc cgtttgcttc
    19021 acctttatcg tagctcagac ttagccccac accgtcggca cgtacgccac cccatttttt
    19081 cccggtattg ctcggggagt ctttttgccc accaaaggcc agcaaagaac tggagatggg
    19141 ccgacggtgg gcgttaacgg tgtaacccag cggcccgata tcatcgctgt aactgatgcc
    19201 gccgaccaca tccaccacgt tgaagcccat cggcgtggta ccgatatccc agctccagac
    19261 gtcatttcgc cagccgaccg ccacgctggc accggaatcc gactggctgc ggttgccgct
    19321 acagtcctgt aatgtacagg tgccccagtt gtcatcccat ttgccatcgg cattagtgga
    19381 gaaactgccg acgttcatat tgacgaaatc actgcgaaag aacatccgcc cgtcagaata
    19441 cggcgcatcc acctgcaaca tggtagtgtg cgctttcaga tcggagtaac caccggtgcc
    19501 gctcgaaccc cagtaatcgt gctcaagggt gacgttaaga tcctgctggc gatagaggtc
    19561 cgccgcatcg ctgcgcacgc cgcgtttcag ccagtcatct ttctcgtcgt tacgggtcag
    19621 tcgggtgaat gtgtcgttat cctgcggacg cgtcgtagtc acaccagatg cgaccatggc
    19681 gtctttgtag gtttccagcg cctgctttgg atcgcccgcc tgcgcttcaa acttcgcacc
    19741 gtcgcgcagc accatcgcgc tttccatcga cggtggctga gattttgcct gcgggatcaa
    19801 cttattaaac gtctgctgcg ccgctgcggt atctccaagc tgcgcctgcg ccagcgccac
    19861 gcgccgctgt gtgttcagcg aggcgttatc ggtagcgggc agtttcgcca gctggctacg
    19921 tgccgccgct gtgtcaccgg cagcaatatc cacttccgtc agccccagaa tggcatcggc
    19981 gttagttggc tcccgcgtca ggacattctg atatgcagcg cgggcggcgg tgtaatcacg
    20041 tcgctgctgc gcccagtcag ccagcgtgag gtcaatacgc gtggaaggtg gttgctgacg
    20101 cagcatcgct tccgcttcag cttctttgcc gctttctcgc aggcgattag cagtttccag
    20161 cacctgatcg ctttgcagtc gattaaccag ctcctgaata ttgctgttcc actgcgcgcg
    20221 cggcaggctg ttgatatgcg ccagcgccgc tctgtcctgg tcatgaccag agaggtacag
    20281 cccgtaagcg taaacctgct ccgggtcgtt cggcttctgc tgcgccagat tgcgcattaa
    20341 cgtatcggcc tggctgcgtt gtccggcctg ccagagatcc tgcgaaagtc ggtaagtaat
    20401 ccatacgctg ccggggtcca gcgccagtcg ttgccgctga agtgctgccg cctgcgccca
    20461 tttgccctgg ttttccagtg cctctgcctg ctgtgccaga cggtcgtttt gcaggctgcg
    20521 ttcgatatca tcaatgctac gccgctgact ggcagagagc gaggcgataa acgcttcagc
    20581 tttttctggc gattgctggc ggtaaatatt tgccagcccg cgcacggcgt tagtgttgcc
    20641 gctgtccata cgcaaggtct gctgataata acgttcggcg gcgggataat cttttcgcgc
    20701 catcgccaca tcgcccagcc ccagcactgc ataactgtcg gtgttatcga cattacgcgc
    20761 ctgctggaac aggcgttctg cccggtcagg attattggct ttcagcgcag catcgccctg
    20821 ctggatcgcc agccagtagc ggtttacttt cagcagactg ttccatttgt cgttgttgct
    20881 gctgtgcggg tccagtgcga gggctttttc cagattcgcc actgcattgg cgcgatcgcc
    20941 tttctgagaa tacgcctggc ccagcgcccc cagagcttca ctgtctttcg ggttcgcccg
    21001 caccgcctgt tgtagttcgg gaatggcttt acccgccata ccagagtcca ccgccgctaa
    21061 accttgcgca cgagcgcgga aagcaggatc ggccagctgt ttttgctgtt ctgccagttg
    21121 cgattgcgca gccgccacgc tatcgccatc actaaagatc gagagatatt ttttcagcgc
    21181 cgacacactg gcatcactga cgggcatgtc tttaatctgc ccgtaccaga ttttagaggc
    21241 cccttcgcgc ccggcgttcg attttgccat ctgttccagg acggcaaaac cttcgtcacg
    21301 gcgatcgcta ctaaacagca atagcgccag attgttttgc aggcccgtat tgcccggtgc
    21361 atccgcattg atgcgtttta actgattaat cgcttcgcca cggcgagccg gaattttcgc
    21421 caccgtactc cagtactcga cagcaatgtc accttccggc ggcgcaccgt tgaacagttt
    21481 gttgtaactc gccacagctt cttctgcatg accggtcgtc gcctgcaatc gtgcctgttg
    21541 cagtgcctga cgaccatccg gcgtggaaag tagcatcgta gtccgcgacg atttatacgc
    21601 atttgaactc ggcgctaact gcgacagccg atcgagctgt ttttgcgcgc catcaatatc
    21661 gccctgacgt aacaaagaac ggaaacgggc ggcaacgacg tccgggttat tcggatcaat
    21721 aagttccagc cgatataacg actgttgcac cagatcttca cgatgggtcg cttcgcctaa
    21781 ccgaacttgc tccagcaact gttgctgagc ggttggtgct gcctcgacca tcggcatgac
    21841 ggccagaccg agggaaagcg tgaatatgtt tagtgtgaat ttgcgcattc ctggccccag
    21901 tcaggtaata actcaccttt tgtcgagaag cggaaacggt gttgatccca gccttgtcca
    21961 aacagggtca gcacatagtt gtaataggca tcgctgccgg gaaagttatc ggccacgcgc
    22021 tggcgctgaa cggcctgcgc atcgcggttt tgtaaaaagg gcagcatggc ggcagaaaaa
    22081 ccgaccggtc ctttaccctg cgctttcccc gtagccacat ccactttttc cggcggataa
    22141 ccgtttttct cagtgaatgt cgccatcggt ttaaaccggt tgagcatccg cgctttttgc
    22201 ggatcgctgt caggcatcat gcctacccac atgtaaacgc ggatagcgtc gtagctgctg
    22261 atcaatgttt tttcggcttt tagctgccag cctttgtctt tctcatagcg cacccagtct
    22321 ggcgaaaaac ctttcggggc ggtttccagc aataaacgtt gattggtttc gcgcagcgtg
    22381 gtccacggcg cgccaaagcg ggtgaaatac tgcgccagcg tcggcggcag gtagctgggg
    22441 ttaaaacgcc agctgttatc ctcagcaaaa cccactttgc ccggtaacaa catggaaccc
    22501 agcccaggca ccgtcaccac ttcctcccgc gcgatacgtt ttagcaacgc gctgccgatg
    22561 tcggtataac gctgctcttt ccacaaacgc cccgcctcca gcaacgacca ggccatccag
    22621 acatcaccat cggaggccga attgctgtcc agcacttccc acttactgtt ctctttcttg
    22681 ccccacagcc aggcgggcaa acgttctttt aaagagccct gagcgagatt gttctgcgtc
    22741 cagtcgagaa tattatcgaa agctacacgg tcgttagccg ccagggcaaa gaacataccg
    22801 taactttgcc cttcggaggt ggtgattttg cgcgcgtcgc tggggtcgat gacgcgccct
    22861 tcctgactga tgtaatcctt tttaaactgc tcccaggcag gccaggtaca ggctgcctga
    22921 acactaaagg cagccaacag cagcatcgtc acgattccac tacgcaacac attcatcttc
    22981 aattactcgt tatccgggtt aagacgacga cgactaataa ttcgcagcag acgccacagt
    23041 acccatgcca gcaatatcac actgatagcc gccagcaccg ccagcagaat cggatggttt
    23101 gccagcgcat accacaagcg ctcgaaccac ggcagatgac ctacgtaata aacgtcgcca
    23161 acacgtaggc tgttgatacc ggactcgcgg atcaccgcga ccgaaccgaa catggtggcg
    23221 cgtttgccgc tatcgttcac cgcatcgtta agcatttcat aaccgcgtgg gctatctgcc
    23281 aacagcgcaa tcacgctgcg ctggtcgtta tacggcgact ggaagccaat caccgccgcc
    23341 atcgcaccgg aagaggtcag cgttgaccgg gtttctgccg cgcgatcgct ctcgtccggc
    23401 acaatgccgg ggaacggggt ctggcgcatc ggtgttttca cccagctttc ggtcgcctgc
    23461 accaataggt cgatctgctt atcgtctttc agtttgtccg ggataccacc gatgatcatg
    23521 atgtcggcat ctttgccctg aatggtgctg ccatcatcgg tcaccgtcag attaatcgcc
    23581 gggaagcccg tctgtgcgcc gataaaacca acagtattca gcaacgtttc catctgtgct
    23641 tcgttaggcg ctttcggcat cacggtgatg gtttgcgaca gatccgccat ccggctgaat
    23701 gggaagcccg cgttagcaaa ggcgcgtaga tccggcatcg ggatgaagtg gtaatacttc
    23761 gagaagtcga tggtggagtc gtcaccaatc accacatgat tctgcaccgg ctggaaggta
    23821 atacagttat ccaccgaacc gcccggcatc gggttcatat actcaaagtc gaagcgcagc
    23881 tggttggtcg cgcccagttt cagcgccgga atagagacat ctgttttgcc atccagcaaa
    23941 ccttgtaata ccggaatccg cagcagcagg cggttcgcct cctgtttgct gctcaggttg
    24001 aaggattgca ggaactggtt attcaggctg atatccatcc gcgaactgtc tttcaccggc
    24061 ggcatggtgt agcggtaatt aatatccata tcaatgccgg tactgcgcat caggtagaga
    24121 tccggcggca ggtttagcga aacgttaatc gctgctggct caagaccgct ggattgtaac
    24181 tgttcttcat aggttttcag ttcgccaaat gtgaccggac gatcggtacg tacccagttc
    24241 ggcgcatcgt acggcttacg cggtagcagc ggtttcactt cattcactac cacgctttca
    24301 ccacggaaca gaatgttacc ctgagcgata cctttcgctg cctgcaacag gtctttgtcg
    24361 tcacgaccaa acaccaccag cagtttgacg taaggattct gcggatggtt aatcatctca
    24421 atcacagggg cttttaccgc cggatgatcg cgcaggaagt ccggccgttt gtcgttggtt
    24481 gcaaagacaa tggcattgcg atccggcagt tggttataga gtaccgggaa gttctgccca
    24541 cgccagccag aacgcgaacc aaaccacgag gcgacaatgg cagaggcttg ttgcagccca
    24601 acatccggcg cacccgcaaa gaccatcggc aaggtgttgg tgcggttatc acgcggatca
    24661 aagaatggca ccgggaagtg tgacaggtca ttcttcacat tcagggtctg ataggtcaga
    24721 tccagtccac tgctccgccc aacatccagc caaagcgtgg tgctggccgg gttttcgcac
    24781 acgtcctgat aatggccgac aaactccagc cgcacacggt tgaagtcggt aataaacagt
    24841 gggttaatgg gcatttgcgc cagcgttttt ttacccaact gttctttggt cactggcagc
    24901 acgcccatca gctcatcatt gagataaacc tttaactgcg actggacagg cagtaacgat
    24961 ggcgatggcg tgtattcgag gttgagcatc gccttcgtca ccacttcatc gctgcgcata
    25021 ccaaactcaa tgctgccgtt cgggttaatg ccacgtagca ccatgctgcc cggcggcggc
    25081 gcaatttgcg caaaggtcag cttcacatca cgcgaaggac cgttctgcgc cacgactggc
    25141 gcatcagcgc cctgcacgcc cagcatcact tgccccacct gcggattttg ttccgtctgg
    25201 gcggctacag ctggctcagc attgatcagt ggttgcgttg ctggcgtcgc ctgcgtcatg
    25261 aaagagggga acgcactcat ccccatagcc actgcacaaa tccagaatag ttttcttttc
    25321 atcgcgttat catcattgtt gagccaaagc ctgatccgat ggttgtgccg tttcgctccg
    25381 ctccgggcgg cgcggaataa acgatacaac ccaggaaacc agagaagtca gcacacggaa
    25441 tatgcccttc accgaagaag gcgcaaactc cgccagatgg cggtagccac ggaagccgag
    25501 cttcagaata tccagcagac tttccagcgg cttatcttcc gggtagctgt cctgccagag
    25561 cgcccatgta tccgcacggg caaacgtaca ctgcacaaaa tcgatatgtt gctgggtggt
    25621 gagcggcatt aatttcagcc caacttcatt acccatcacg cgcgccacct gggtcgggaa
    25681 gacgtattcc tgctgaccgc gtttaagcaa cagattcact ttctgccctt ccagaatctg
    25741 cgcctgaccg ttgatcttga tccccaaacc accgtcggag aaatcctgaa cggtacacga
    25801 gaagaggtga ccatcttcgc gggcaattgc cgcgggcatc gtcatctcca cgcggtgcga
    25861 tcggcgtacc tgtttgcttt ctaccgatac cgcaactgcg ccgccaagaa caatcaggtt
    25921 gtagaacacc cacaccatac tgacgaccac ggtgagcatc tcggttggcg ggccatagaa
    25981 gtagcgccag atgcctaccg caacgcccac caggttgagt agaacaagga agatgtaggg
    26041 ccgcgagatc acccagtcga cgtactcttc ttccaccagt ccacctttgg cggtgacgtt
    26101 aaatttgcct ttgtgcgggt taatcagcgc caccagcgtc ggtggtgcga tataccacgc
    26161 cagcaccgtt tcgtagattt cactccagaa agagtggcga tatttgccct ggatcttcga
    26221 gttggtcagg ctggcatgga tcatatgcgg cagcacgaac agggcgatca tcaacgctgg
    26281 cgcatagatg atgtaggcat gaagcagcag gaacgccagc ggcgcagtca ggaagatcag
    26341 tcgtggaatg cccgacaaga agtggaacat ggcgttgacg tagcacagcc gctgggcgaa
    26401 tttcagccct ttaccggtaa gcgggttatc gagacggaag atttgcacca tcccgcgtgc
    26461 ccagcgaata cgctgaccga tatgcgccga cagactttcg gtcgccagcc ccgccgcctg
    26521 cggaatacgc atatatgcag aggtgtagcc acgacggtgc aggcgcagag acgtgtgcgc
    26581 atcttcggtt accgtttcga cagcaatacc gccaatttca tccaatggtt tgcgacgaat
    26641 tactgcacag gaaccgcaga agaaagtggc gtcccacata tcgttgccat cctgcaccag
    26701 accatagaac agcgtgcctt cgttcggtgt tttacggaaa cgccccaggt tgcgttcaaa
    26761 cgggtccggc gagaagaagt ggtgtggaat ctgcatcatc gccagctgtt tctctttcag
    26821 gaaccagccc atggtcattt gcaggaacga tcgcgttggt acgtggtcgc agtcgaaaat
    26881 cgacacgaac tcgcctttgg catatttcag cgcattgttg atgttgcccg ctttcgcatg
    26941 ttcatgagtg gtgcgggcga tatatttcac ccccacgttt tgcgcaaact ggcgaaactc
    27001 ttccctgccg ccgtcatcga ggatccagat gttcagtttg tctttcggcc agtcgatacc
    27061 cagcgaggcg taaatggtat ttttcaccac attgagatct tcgttgtaag tcgggacaaa
    27121 gatatccacc gacggccaca gcgacatatc cttcggcaat ggcaccggct gacgattcag
    27181 cggccatact acctggaagt agccgagcac cagcacaatc cacgcgtacg tttcagcgaa
    27241 gagcagaata agcccgcaca ccaggctgac cggatcgtcc cagttcagcg tagaggtgta
    27301 acgccaccag atataacggc aagaaacggt cagcgacagc acaatcaaca ttagcgccga
    27361 gaagcgcccc ggcatccgcc gtacgatcag cgctacaccc cacagcagca tcaggaagat
    27421 aaactgcgcc agcgggttaa acggttgagt aacgcagatt aacgccagaa tcagcgagaa
    27481 ggtgacgatg ataccgagga tcaaccgccg cgccccggca ctcaaatgac cgagctcttt
    27541 tttctcatca agatgctgtg ttttatggct aacgcgctca ggcagctcgt tcatccattg
    27601 atggtaacgt ccacgaatat tctgcagacc tgaaaatgcc cgcctgcgcg gtttcggcgt
    27661 ttctttgcgc gatgtaccga tcagtaacca gcatgtttga atgagataac ggaccgggtc
    27721 cagcggacgc ggacgcgagg cgttgatatg cggatacagg tttttatgtt ctgcgcgaat
    27781 acgctgccag cgcgggtgct ccagcggaat aaaaatccag gccaggatca tccagaaaca
    27841 gccgagcgtc gcgctgaaag ccgacgcacc gtgacgacga taatcgcgat aacgcccgat
    27901 aagccgcgcg ttgaccggcg ggataagcaa ccaccgggtc aggatactca tgatgcactc
    27961 ccgactggcg ttttcagccc ggagtagttc aacaggcacc agttcgccag cgtcagtatc
    28021 tcttcagccg ccagcgcatc actgcgatat tcacctactg gttgcttagc cgccaggcat
    28081 tcagccatcg cttcatcacg atgaatgagc atcggcagta atcggcgctg gctttgcaac
    28141 caaagctggt aaatatcgtc ctgaacctga ctgccaatac ggaagttatt aatcaaaata
    28201 tgtgcgccat ccggcagcgc ttgctgatgc agtcggatat ggcagttggc atccacattg
    28261 acgattgcca gcgagtgatc gcacaaactc agcagctggt gggttatctg cgaggcatca
    28321 cgcggtaagt cgattaaaat ccactggtaa cgcccgctgg cttttagttg ctgtaagccg
    28381 gagcaaatat cgctcagccg ggtttgccag tgctgtggat tttcttgttc ttcaatggat
    28441 aactgaccaa aaggcagcaa atcgagctgc gaggtgtagc gcaacccagc gtcacgccag
    28501 tcctggccat ccagcatcgc tctggcccag ccctgacggt gggtaaaatc aacattaaat
    28561 gacaggcgca acaagttgtc cgggcaggca tcgaccacca gaacattttc tcccaacatt
    28621 tgtaatgacc aggctaatgc ggcggtgatg gttgttgtcc ccacgcctcc ccgcaccccc
    28681 tgcaatccca gtacggccat tcaccaatcc cctacttttg ttgcgcaaac tctgccagca
    28741 acggccagcg ttttaatgcc gcggccaact gttcgcgttg ggaaatatcg gcataatcaa
    28801 tatcaggcag tgaaaatgcc tgctttaacg ccacaatatc attctggaag atatagccta
    28861 tcgcgggatc aggcagagta tctggttcat tgttattcat tttgcttgat ccctatgaaa
    28921 taaccgtacc gttcatgaga caattctaac cgtgagcatt tcgccggttt attgtttacg
    28981 gcgagacggg aatttgctca ctttttgact ttccgttacg caacagaaaa agttaaaaac
    29041 gaaaagacta aaatcacacg tcttgtgacc ttctaaattg attcacatgc taaatctgat
    29101 aagttttaat ttcaatggta ggtttatttc ttagctttcg ctagtaaact gataatcaga
    29161 caaaatggtg acatgaggga cattgtggac cctgtattct ctatcggtat ctcatcatta
    29221 tgggatgagc tgcgacatat gccagcaggc ggcgtctggt ggtttaacgt cgatcgccat
    29281 gaagatgcta tcagtctggc gaatcaaaca attgcatccc aggctgaaac cgcacacgtc
    29341 gcggtcatta gcatggacag cgatccggcg aaaatctttc aattagatga ttctcaaggg
    29401 ccggaaaaaa taaaattatt ttcaatgcta aatcatgaaa aaggtctata ctatttgacc
    29461 cgtgatttgc agtgttctat tgatccccat aattaccttt ttattcttgt ttgcgcaaat
    29521 aacgcatggc aaaacattcc tgccgagcgg cttcgctcat ggttggataa aatgaataaa
    29581 tggagcaggt taaaccattg ttcgcttttg gtaattaatc ccggaaataa taacgataaa
    29641 caattttcat tgttgcttga ggaataccgt tcactttttg gtcttgccag tttgcgtttt
    29701 cagggtgacc aacatttgct ggatattgcc ttctggtgca acgaaaaagg ggtcagcgcc
    29761 cgtcagcagc ttagcgttca gcaacaaaat ggtatctgga cattagttca aagcgaagag
    29821 gcggagatcc aaccacgcag cgacgaaaaa cgcattctga gtaatgttgc tgtactggaa
    29881 ggtgcgccgc cgctatcgga acactggcaa ctgttcaaca ataacgaagt cctgttcaat
    29941 gaagcccgta ccgctcaggc ggcgacggtg gtcttttctt tacagcaaaa tgcgcaaatc
    30001 gagccactgg cccgcagcat tcataccctg cgtcgccagc gcggtagtgc gatgaaaatc
    30061 ctcgtgcggg aaaataccgc tagcctgcgc gccaccgatg aacgtttgtt attggcctgc
    30121 ggtgcaaata tggttattcc gtggaatgcg ccactctccc gttgtctgac gatgatcgaa
    30181 agcgtgcaag ggcagaagtt tagtcgctat gtgccggaag atatcactac cttgctgtca
    30241 atgacccagc cgctcaaact gcgtggtttc cagaagtggg atgtgttctg taatgccgtc
    30301 aacaacatga tgaataaccc tctattacct gcccacggta aaggcgttct ggttgcccta
    30361 cgtccggtac cgggtatccg cgttgaacaa gccctgacgc tgtgtcgccc taaccgtacc
    30421 ggcgatatca tgaccattgg cggtaatcgg ctggtgctgt ttctctcatt ctgtcggatt
    30481 aacgatctgg ataccgcgtt gaatcatatt ttcccattgc ctactggcga cattttctca
    30541 aaccgtatgg tctggtttga agatgatcaa atcagtgccg agctggtgca gatgcgcttg
    30601 cttgccccag aacaatgggg catgccgctg cctttaacgc aaagttctaa accggtcatc
    30661 aatgccgagc acgatggtcg ccactggcga cgaataccag aacccatgcg actgttagat
    30721 gatgctgtgg agcgctcatc atgatgacca tcagcgatat cattgaaatt attgtcgttt
    30781 gcgcactgat atttttcccg ctgggctatc tggcgcggca ctctttgcga cgcattcgcg
    30841 acaccttacg tttgttcttt gctaaacctc gttatgttaa accggccggg acgttacgcc
    30901 gcacggaaaa agccagggca accaaaaaat gactcaattt acgcaaaata ccgccatgcc
    30961 ttcttccctc tggcaatact ggcgcggcct ttccggctgg aacttctatt ttctggttaa
    31021 gttcggcctg ttgtgggcgg gatatcttaa cttccatccg ctcctcaatt tggtgtttgc
    31081 cgcgtttctg ctgatgccca ttccgcgcta cagcctgcat cgcttgcgcc actggattgc
    31141 cctgccgatc ggctttgctt tgttctggca tgacacctgg ttgcctggcc cggaaagcat
    31201 aatgagccag ggttcgcagg tggcggggtt cagtaccgat tatttaatcg accttgtcac
    31261 acgctttatt aactggcaga tgattggggc catttttgtt ttattagtgg cctggttatt
    31321 cctgtcacaa tggattcgca ttaccgtttt tgtggttgcc atactgctat ggctgaacgt
    31381 acttaccctg gcgggaccaa gtttctcctt gtggccagcc ggacaaccga cgaccactgt
    31441 aacaacgacg ggtggtaacg cagcggcaac cgttgcggcg acgggtggcg caccggtagt
    31501 gggtgatatg cccgcacaaa ctgcaccgcc aacaacggcg aaccttaacg cctggctgaa
    31561 taatttctat aacgcggagg cgaaacgtaa atcgaccttc ccgtcttcgc tgcccgctga
    31621 tgctcagcca tttgaactac tggtgattaa catctgttcg ctttcctggt cggatataga
    31681 agccgccggg ttgatgtcgc atccactgtg gtcgcatttc gatattgagt tcaagaactt
    31741 taactccgcc acctcctaca gtggcccggc ggcgatccgt ttactgcgcg ccagctgcgg
    31801 gcagacttcg cacactaatc tgtatcaacc ggcaaataac gactgctatc tgtttgataa
    31861 cctttcgaaa ctgggcttta cccagcacct gatgatgggg cataacggcc agttcggcgg
    31921 ttttttgaaa gaagttcgcg aaaatggcgg catgcagact gaattgatgg atcaaacaaa
    31981 tctgccggtt attttgctgg gctttgatgg ttcgccggtt tatgacgata ccgccgtgct
    32041 taaccgctgg ctggacgtta ccgaaaaaga taaaaacagc cgtagtgcca cgttctacaa
    32101 cacgcttcca ctgcatgacg gcaaccatta tccgggggtc agcaaaacag cggattacaa
    32161 agcgcgggcg cagaaattct ttgatgaact ggacgccttc tttactgaac tggagaaatc
    32221 gggtcgtaaa gtgatggtgg tcgtggtgcc ggaacacggc ggcgcgctta agggcgacag
    32281 aatgcaggta tctggcctac gtgatatccc tagcccgtct atcacagacg tccccgttgg
    32341 ggtgaaattc ttcggcatga aggcaccaca tcagggggca ccgattgtca ttgaccaacc
    32401 gagcagcttc ctggctatct ccgatctggt ggttcgcgtt cttgatggca agattttcac
    32461 cgaagacaat gttgactgga aaaaactcac cagtgggttg ccacaaacag caccggtctc
    32521 cgagaactca aatgcagtag ttattcaata ccaggataaa ccgtacgttc gcctgaacgg
    32581 cggcgactgg gtgccttacc cgcagtaagc acgaaaaagg ccgcagagtt taacctctgc
    32641 ggcctgatcc gggcgcaaat tgccattacg gcagcctgac gcccgcatga cacgttactt
    32701 ccgcttattc agccagttca cgatcatact ggcaagaatg ccagcaatga ccggagccgc
    32761 taaatcatgc cagaaggcca tgcccagctc tgcgagcgtc atatagccgc ctgtgttgta
    32821 atgacaacgt ttcgcggcta ttcttgagtt gtttgggttc aagattagcc cccgttatgt
    32881 tgtcaggtgc atacctgcaa cgtgcggggg ttttctctct ccagcaacca atgccaccag
    32941 ggataaagcc cccgcaacat tgcgcctcac cggaaccttt ccggcttgcc gctgattcta
    33001 cgactgtttt tctgttccga aatccatcac ttactcactc tgtgctgcgc attccgcaga
    33061 atattatccg cctgcaaccg ttgcattttt cttacgaaaa aggccgcaga gtttcacccc
    33121 tgcggcctgg tccgggcgca aattgccatt acggcagcct gacgcccgca tgacacgtta
    33181 cttccgcttg ttcagccagt tcacgatcat actggcaaga atgccagcaa tgaccggagc
    33241 cgctaaatca tgccagaagg ccatgcccag ttctgcgagc gtcatatagc cgcctgt
//
LOCUS       DAZUDJ010000054        32339 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.054, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000054 DAZUDJ010000000
VERSION     DAZUDJ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32339
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.054"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(147..944)
                     /gene="rfaP"
                     /locus_tag="ACHY1N_003358"
     CDS             complement(147..944)
                     /gene="rfaP"
                     /locus_tag="ACHY1N_003358"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312532.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HFS4045605.1"
                     /translation="MVELKEPFATLWRGKDPFEEVKTLQGEVFRELETRRTLRFEMAG
                     KSYFLKWHRGTTLKEIIKNLLSLRMPVLGADREWNAIHRLRDVGVDTMYGVAFGEKGM
                     NPLTRTSFIITEDLTPTISLEDYSADWATNPPDVRVKRMLIKRVATMVRDMHAAGINH
                     RDCYICHFLLHLPFSGKEEELKISVIDLHRAQLRTRVPRRWRDKDLIGLYFSSMNIGL
                     TQRDIWRFMKVYFAAPLKDILKQEQGLLSQAEAKATKIRERTIRKSL"
     gene            complement(937..2061)
                     /gene="waaG"
                     /locus_tag="ACHY1N_003359"
     CDS             complement(937..2061)
                     /gene="waaG"
                     /locus_tag="ACHY1N_003359"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFS4045606.1"
                     /translation="MIVAFCLYKYFPFGGLQRDFMRIAQTVAARGHHVRVYTQSWEGE
                     CPDVFELIKVPVKSHTNHGRNAEYFAWVQKHLREHPVDKVVGFNKMPGLDVYYAADVC
                     YAEKVAQEKGFFYRLTSRYRHYAAFERATFEQGKPTQLLMLTDKQIADFQKHYQTEAE
                     RFHILPPGIYPDRKYSQQPANSREIFRKKNGITEQQYLLLQVGSDFTRKGVDRSIEAL
                     ASLPDSLRHNTLLYVVGQDKPRKFEALAEKRGVRSNVHFFSGRNDVSELMAAADLLLH
                     PAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIVDANCGEAIAEPFRQETLNEILRKA
                     LTQSSLRQAWAENARHYADTQDLYSLPEKAADIITGGLDG"
     gene            complement(2058..3116)
                     /gene="rfaQ"
                     /locus_tag="ACHY1N_003360"
     CDS             complement(2058..3116)
                     /gene="rfaQ"
                     /locus_tag="ACHY1N_003360"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HFS4045607.1"
                     /translation="MDKPFRRILLIKMRFHGDMLLTTPVISSLKKNYPDAKIDVLLYQ
                     DTIPILSENPEINALYGIKNKKAKASEKIANFFHLIKVLRANKYDLIVNLTDQWMVAI
                     LVRLLNARVKISQDYHHRQSAFWRKSFTHLVPLQGGNVVESNLSVLTPLGLDSLVKQT
                     TMSYPPASWKRMRRELDHAGVGQNYVVIQPTARQIFKCWDNAKFSAVIDALHARGYEV
                     VLTSGPDKDDLACVNEIAQGCQTPPVTALAGKVTFPELGALIDHAQLFIGVDSAPAHI
                     AAAVNTPLISLFGATDHIFWRPWSNNMIQFWAGDYREMPTRDQRDRNEMYLSVIPAAD
                     VIAAVDKLLPSSTTGTSL"
     gene            3529..4806
                     /gene="waaA"
                     /locus_tag="ACHY1N_003361"
     CDS             3529..4806
                     /gene="waaA"
                     /locus_tag="ACHY1N_003361"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HFS4045608.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRH
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQ
                     HVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSA
                     AGYAKLGKFVRRLLRRITLIAAQNEEDGARFVALGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLAKEVSSLLTDADYRS
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            4814..5293
                     /gene="coaD"
                     /locus_tag="ACHY1N_003362"
     CDS             4814..5293
                     /gene="coaD"
                     /locus_tag="ACHY1N_003362"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFS4045609.1"
                     /translation="MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKP
                     MFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQL
                     AHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA"
     gene            complement(5332..6141)
                     /gene="mutM"
                     /locus_tag="ACHY1N_003363"
     CDS             complement(5332..6141)
                     /gene="mutM"
                     /locus_tag="ACHY1N_003363"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HFS4045610.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRL
                     SDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVELVMSNGKV
                     LRYTDPRRFGAWLWTKELEGHNVLTHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK"
     gene            complement(6239..6406)
                     /gene="rpmG"
                     /locus_tag="ACHY1N_003364"
     CDS             complement(6239..6406)
                     /gene="rpmG"
                     /locus_tag="ACHY1N_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFS4045611.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            complement(6427..6663)
                     /gene="rpmB"
                     /locus_tag="ACHY1N_003365"
     CDS             complement(6427..6663)
                     /gene="rpmB"
                     /locus_tag="ACHY1N_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFS4045612.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY"
     gene            complement(6880..7548)
                     /gene="radC"
                     /locus_tag="ACHY1N_003366"
     CDS             complement(6880..7548)
                     /gene="radC"
                     /locus_tag="ACHY1N_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418095.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFS4045613.1"
                     /translation="MKNNSQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTL
                     AKEMLENFGSLYGLLTSEYEQVSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLL
                     SPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAI
                     KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAE
                     RGWI"
     gene            7720..8940
                     /gene="coaBC"
                     /locus_tag="ACHY1N_003367"
     CDS             7720..8940
                     /gene="coaBC"
                     /locus_tag="ACHY1N_003367"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015941 - pantothenate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HFS4045614.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARIAAGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGMLIWGPDSGSQACGD
                     IGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAA
                     VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNV
                     EEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            8918..9376
                     /gene="dut"
                     /locus_tag="ACHY1N_003368"
     CDS             8918..9376
                     /gene="dut"
                     /locus_tag="ACHY1N_003368"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFS4045615.1"
                     /translation="MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRVCLDDAVELA
                     PGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVW
                     NRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ"
     gene            9483..10079
                     /gene="slmA"
                     /locus_tag="ACHY1N_003369"
     CDS             9483..10079
                     /gene="slmA"
                     /locus_tag="ACHY1N_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0010974 - negative regulation of division
                     septum assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HFS4045616.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLAS
                     QILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(10116..10757)
                     /gene="pyrE"
                     /locus_tag="ACHY1N_003370"
     CDS             complement(10116..10757)
                     /gene="pyrE"
                     /locus_tag="ACHY1N_003370"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFS4045617.1"
                     /translation="MKPYQRQFIEFALGKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGLEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEA
                     KDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERG
                     RGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV"
     gene            complement(10823..11539)
                     /gene="rph"
                     /locus_tag="ACHY1N_003371"
     CDS             complement(10823..11539)
                     /gene="rph"
                     /locus_tag="ACHY1N_003371"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFS4045618.1"
                     /translation="MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVA
                     AVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLL
                     ALARGGIESIVATQKAALAN"
     gene            11666..12529
                     /gene="yicC"
                     /locus_tag="ACHY1N_003372"
     CDS             11666..12529
                     /gene="yicC"
                     /locus_tag="ACHY1N_003372"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFS4045619.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELILNEKLAKQLVTAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIVARETEGQALKALIEQRL
                     EGVTAEVVKVRAHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLI
                     EQMREQIQNIE"
     gene            12750..13574
                     /gene="dinD"
                     /locus_tag="ACHY1N_003373"
                     /pseudo
     CDS             12750..13574
                     /gene="dinD"
                     /locus_tag="ACHY1N_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312547.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein D"
     gene            13866..14483
                     /gene="yicG"
                     /locus_tag="ACHY1N_003374"
     CDS             13866..14483
                     /gene="yicG"
                     /locus_tag="ACHY1N_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HFS4045620.1"
                     /translation="MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKVFLVLDALGLVVFSI
                     IGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLY
                     IALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH"
     gene            complement(14480..16162)
                     /gene="ligB"
                     /locus_tag="ACHY1N_003375"
     CDS             complement(14480..16162)
                     /gene="ligB"
                     /locus_tag="ACHY1N_003375"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312549.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
                     /protein_id="HFS4045621.1"
                     /translation="MKVWMAILISILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQW
                     DDDYWKEGKSEVEDGVYDQLSARLTQWQRCFVSEPRDVMMPPLNGAVMHPVAHTGVRK
                     MADKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSL
                     ISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSL
                     GVFVWAWPDGPQLMTDRLKELATAGFTLTQRYTRAVKNADEVARVRNEWWKAKLPFVT
                     DGVVVRGAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLA
                     PVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTP
                     PENRFNSLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFS
                     WLLLTPEQLQNTPGIAKSKSAQLWHRFNLARKQPFTRWVMAMGIPLTRAALNASDERS
                     WSQLLFSTEQFWQQLPGTGSGRARQVTEWKENAQIKKLGSWLAAQQITGFEP"
     gene            16420..17043
                     /gene="gmk"
                     /locus_tag="ACHY1N_003376"
     CDS             16420..17043
                     /gene="gmk"
                     /locus_tag="ACHY1N_003376"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFS4045622.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQP
                     RPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLD
                     IDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            17098..17373
                     /gene="rpoZ"
                     /locus_tag="ACHY1N_003377"
     CDS             17098..17373
                     /gene="rpoZ"
                     /locus_tag="ACHY1N_003377"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFS4045623.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            17392..19500
                     /gene="spoT"
                     /locus_tag="ACHY1N_003378"
     CDS             17392..19500
                     /gene="spoT"
                     /locus_tag="ACHY1N_003378"
                     /EC_number="2.7.6.5"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0008893 - guanosine-3',5'-bis(diphosphate)
                     3'-diphosphatase activity [Evidence IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HFS4045624.1"
                     /translation="MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGV
                     LITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQE
                     FITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLA
                     NIMRKIRVMPDVIKVTRNRN"
     gene            19507..20196
                     /gene="trmH"
                     /locus_tag="ACHY1N_003379"
     CDS             19507..20196
                     /gene="trmH"
                     /locus_tag="ACHY1N_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0141100 - tRNA
                     (guanine(18)-2'-O)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HFS4045625.1"
                     /translation="MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA
                     VDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE
                     SQRQRQNAGMYLRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD
                     ADWWATMQAAG"
     gene            20202..22283
                     /gene="recG"
                     /locus_tag="ACHY1N_003380"
     CDS             20202..22283
                     /gene="recG"
                     /locus_tag="ACHY1N_003380"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFS4045626.1"
                     /translation="MKGRLLDAVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFSAA
                     MKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQH
                     PAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDTLKNKLLAALPFKQTGAQARV
                     VAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFAPLGIEVGWLAGKQKGKARLAQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRTDIIDRVRHACITEGRQAYWVCTLIEESELLEAQAAEATW
                     EELKLALPELNVGLVHGRMKPAEKQAVMASFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIER
                     WMPETERYSNA"
     gene            complement(22268..23134)
                     /locus_tag="ACHY1N_003381"
     CDS             complement(22268..23134)
                     /locus_tag="ACHY1N_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312555.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045627.1"
                     /translation="MKKRRKEPETLREHCRHIFGDEPPVLCVWETEFDYADAELKALA
                     AKEWQQISEWDLSAYYVLNLVYNEPMQIELFRYLFPLCLAQWHETVLAGGYGDHFEES
                     LMKALCRPYLWQEMMNASQRQQVRQFLLDTALQRMDNERGFNNVLCWLAVFNTLGGAA
                     PLIRSLWSRWWALDTPGKAVCAIQYAAHLIYPIEANPLWSQEWIGWGHPLGHKDGWSS
                     DNRAFLRQMLTPEMIVAGVQAAAEILRGEPEGAMAARIAQDAYEAMDILTIQIEDLLR
                     DLSCDESGHALE"
     gene            complement(23137..24342)
                     /gene="gltS"
                     /locus_tag="ACHY1N_003382"
     CDS             complement(23137..24342)
                     /gene="gltS"
                     /locus_tag="ACHY1N_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HFS4045628.1"
                     /translation="MFHLDTLATLVAATLTLLLGRKLVHSVSFLKKYTIPEPVAGGLL
                     VALALLVLKKSMGWEVNFDMSLRDPLMLAFFATIGLNANIASLRAGGRVVGIFLIVVV
                     GLLVMQNAIGIGMASLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFIERYGFTNATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPNGIPDDQEVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTAFELPTFVCVLFVGVILSNGLSMMGFYRVFERAVS
                     VLGNVSLSLFLAMALMGLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAG"
     gene            24622..26013
                     /gene="xanP"
                     /locus_tag="ACHY1N_003383"
     CDS             24622..26013
                     /gene="xanP"
                     /locus_tag="ACHY1N_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HFS4045629.1"
                     /translation="MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNP
                     YLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGIT
                     AIVLNLIFPPEKQ"
     gene            26134..27843
                     /gene="yicH"
                     /locus_tag="ACHY1N_003384"
     CDS             26134..27843
                     /gene="yicH"
                     /locus_tag="ACHY1N_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HFS4045630.1"
                     /translation="MKFIGKLLLYILIALLVVIAGLYFLLQTRWGAEHISAWVSENSD
                     YHLAFGAMDHRFSAPSHIVLENVTFGRDGQPATLVAKSVDIALSSRQLTEPRHVDTIL
                     LENGTLNLTDQTAPLPFKADRLQLRDMAFNSPNSEWKLSAQRVNGGVVPWSPEAGKVL
                     GTKAQIQFSAGSLSLNDVPATNVLIEGSIDNDRVTLTNLGADIARGTLTGNAQRNADG
                     SWQVENLRMADIRLQSEKSLTDFFAPLRSVPSLQIGRLEVIDARLQGPDWAVTDLDLS
                     LRNMTFSKDDWQTQEGKLSMNASEFIYGSLHLFDPIINAEFSPQGVALRQFTSRWEGG
                     MVRTSGNWLRDGKTLILDDAAIAGLEYTLPKNWQQLWMETTPGWLNSLQLKRFSASRN
                     LIIDIDPDFPWQLTALDGYGANLTLVTDHKWGVWSGSANLNAAAATFNRVDVRRPSLA
                     LTANSSTVNISELSAFTEKGILEATASVSQTPQRQTHISLNGRGVPVNILQQWGWPKL
                     PLTGDGNIQLTASGDIQANVPLKPTVIGQLHAVNAAKQQVTQTMNAGIVSSGEVTSTE
                     PVR"
     gene            complement(27896..30214)
                     /gene="yicI"
                     /locus_tag="ACHY1N_003385"
     CDS             complement(27896..30214)
                     /gene="yicI"
                     /locus_tag="ACHY1N_003385"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HFS4045631.1"
                     /translation="MKISDGNWLIQPGLNLIHPLQVFEVEQQDNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAE
                     FKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSF
                     EVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTS
                     FTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRR
                     LKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     DACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTQLK
                     CRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAG
                     DVQFYLPEGRWTHLWHNDELDGSRWHKQQHGFLSLPVYVRDNTLLALGNNDQRPDYVW
                     HEGTAFHLFNLQDGHEAVCEVPATDGSVIFTLKAARTGNTITVTGAGEAKNWTLCLRN
                     VVKVNGLQDGSQAESEQGLVVKPQGNALTITL"
     gene            complement(30224..31606)
                     /gene="yicJ"
                     /locus_tag="ACHY1N_003386"
     CDS             complement(30224..31606)
                     /gene="yicJ"
                     /locus_tag="ACHY1N_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418114.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
                     /protein_id="HFS4045632.1"
                     /translation="MKSEVLSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPA
                     GFVGTMFLVARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPD
                     LSMNGKMIYAAITYTLLTLLYTVVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
                     LSTVLMMPLVNLIGGDNKPLGFQGGIAVLSVVAFMMLAFCFFTTKERVEAPPTTTSMR
                     EDLRDIWQNDQWRIVGLLTIFNILAVCVRGGAMMYYVTWILGTPEVFVAFLTTYCVGN
                     LIGSALAKPLTDWKCKVTIFWWTNALLAVISLAMFFVPMQASITMFVFIFVIGVLHQL
                     VTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLAFGGALIGWMLAYGGYDA
                     AEKAQNSATISIIIALFTIVPAICYLLSAIIAKRYYSLTTHNLKTVMEQLAQGKRRCQ
                     QQFTSQEVQN"
     gene            31899..31993
                     /locus_tag="ACHY1N_003387"
     tRNA            31899..31993
                     /locus_tag="ACHY1N_003387"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31933..31935,aa:Sec,seq:tca)
     gene            32072..32233
                     /gene="rhuM"
                     /locus_tag="ACHY1N_003388"
                     /pseudo
     CDS             32072..32233
                     /gene="rhuM"
                     /locus_tag="ACHY1N_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774140.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RhuM family protein"
BASE COUNT         7998 a         8673 c         8014 g         7654 t
ORIGIN      
        1 ctgtcaatac caaatgctat atcaagagta tttttagatc ttatattttg ataatgaaaa
       61 ttatactcaa aaaggatgat gtcactatca ttgagttgag acatatttat tctgtatcca
      121 aaattttggc aaaaataagt tacgggttac aacgattttc gaatcgttct ttccctgatt
      181 tttgtggctt ttgcttctgc ttgcgacagc agtccttgtt cctgcttgag aatgtcttta
      241 agcggggcgg caaaatacac tttcataaac cgccagatat cccgctgagt caggccgata
      301 ttcatcgaag aaaaataaag cccaataaga tctttatccc gccaacgacg tggaacgcgc
      361 gtgcgaagct gcgcccggtg caggtcaatt accgaaattt ttaactcctc ttccttaccg
      421 gaaaaaggca agtgcagcag gaaatgacag atataacagt cacggtggtt aatgcccgca
      481 gcatgcatat cgcgcaccat cgtcgcgaca cgcttaataa gcatacgctt tacgcgaaca
      541 tctggagggt tagtcgccca gtcagcactg taatcttcaa gacttatggt tggtgtcaga
      601 tcttcggtaa taataaatga agttctggtc agcggattca tgcctttttc gccaaatgcc
      661 accccataca tagtatcaac gccgacatcc cgcagtcgat gaatcgcatt ccattcgcgg
      721 tcagcgccta atactggcat ccgcaatgag agtaaatttt tgattatctc tttcagggtc
      781 gtgccgcgat gccatttgag aaaatagctt ttgcccgcca tttcaaagcg cagagtacgg
      841 cgagtttcca gttcacgaaa tacctcaccc tgcaaggttt taacttcctc aaaaggatct
      901 ttgccgcgcc ataacgtggc aaacggctct ttaagttcaa ccatccagac cacccgttat
      961 gatatccgcc gctttctctg gcagactgta taaatcttgt gtatcagcat aatgtcgcgc
     1021 attttccgcc caggcctggc gcaatgaaga ttgcgttaac gctttgcgta aaatctcatt
     1081 caatgtttcc tggcggaatg gctcagcaat agcctcgccg caattagcgt cgacaatata
     1141 atgcgcatag ccacaaacgg ctgttgttag taccggtaat cctgcagtaa tcgcttccag
     1201 cagcacaatt cccgccgctt cctggtaggc aggatgcagt aataaatccg ccgccgccat
     1261 taattccgag acatcattgc gccccgagaa aaagtgaaca ttactgcgca cgccgcgttt
     1321 ttctgccagc gcctcaaatt ttcgcggttt atcctgccca acaacatata gcaatgtgtt
     1381 gtggcgcagc gaatccggta acgaagcaag tgcttcaatg gaacgatcga cacctttacg
     1441 cgtgaagtct gaaccgacct gcaacaataa atattgttgt tcggttattc cattcttctt
     1501 acggaagatt tcacggctat tggctggctg ctggctatat ttacgatcag gataaatccc
     1561 cggtggcaga atatgaaaac gctccgcttc agtctgataa tgtttctgga aatcggcgat
     1621 ttgcttatct gtcagcatca gcaactgtgt cggcttaccc tgttcgaagg ttgcccgctc
     1681 aaaggcggca taatggcgat aacgtgacgt caggcgatag aaaaagcctt tttcctgcgc
     1741 tactttctcg gcataacaaa catcagcggc ataataaacg tccagccccg gcattttgtt
     1801 gaatccaacg actttatcga cgggatgttc gcgtaaatgt ttttgcaccc aggcaaaata
     1861 ctccgcattg cgcccgtgat tggtatgcga tttaaccggc actttgatca gttcaaatac
     1921 atcagggcat tcgccttccc acgactgggt ataaacccga acatgatgac ctcgggcggc
     1981 gactgtctga gcaatacgca taaaatcacg ctgcaaaccg ccaaagggaa aatatttata
     2041 taaacaaaaa gcaacgatca taacgacgta cctgtcgtgg aggagggcag taatttatcg
     2101 acagcagcaa tgacatctgc cgccggaata accgaaagat acatctcatt tcggtcacgc
     2161 tgatcgcgcg ttggcatttc ccggtaatct cccgcccaga attgaatcat gttatttgac
     2221 cagggacgcc agaaaatatg atctgtcgca ccaaacagcg atatcagcgg cgtattaact
     2281 gcagcggcaa tatgcgccgg tgcggaatca acgccaataa acagctgcgc atgatcgatt
     2341 aacgcaccaa gttccgggaa ggtcaccttt ccagccagcg ccgttactgg tggcgtctgg
     2401 catccctgcg caatttcatt gacgcaggcc agatcgtctt tatctgggcc ggacgtcaga
     2461 acgacttcat aaccacgagc atgtaaggca tcaatcacag cggaaaactt ggcgttgtcc
     2521 cagcatttga agatttgccg cgccgtaggt tggataacca cataattttg tccaacacca
     2581 gcgtgatcaa gttcgcgacg catacgtttc cagcttgcag gcgggtaact catggttgtc
     2641 tgcttcacca acgaatcaag tcccaatggt gtcagcacgg ataagttact ttccaccaca
     2701 tttccaccct gcaacggcac caaatgggtg aaacttttac gccaaaaagc agactgccga
     2761 tgatgataat cctgggaaat tttcacacga gcatttaata agcgaaccag tatagcaacc
     2821 atccattgat cggtaagatt gacgataagg tcatacttat tggcacgtaa taccttgatg
     2881 agatgaaaaa agttggcaat tttttctgag gcttttgctt ttttattttt tatgccgtag
     2941 agcgcgttaa tctctggatt ttcagacagg atcgggatgg tgtcctgata aagcagcaca
     3001 tcgatttttg cgtcagggta attttttttc agcgaactaa tgacgggagt agttaataac
     3061 atatccccat gaaaacgcat cttaatgagc aaaattcttc gaaatggctt atccacaagt
     3121 aactcttttt gttgagatta tccgattaag gtgaagcaga aaaagcacgc taccgcccca
     3181 ggctcaacag ctacctgaat actgataccg cactgatatt gacgcgctag tgtatcactt
     3241 ctttcgcggc aatccgaccc gaatgatttt taagcacatt gttgattttc aataaagaaa
     3301 tcaatcaaat aaaatcatta gcaaccatat tctttcactg ttgctctgcg attccttcct
     3361 gcacgtacag cagaaatcaa tgaatcgcat aaaaatacaa aaaaagtata gatgttcagc
     3421 aagaattggc gggtaaattg ctatttaagt caaaaacggg aaaagtaatg gtaaagccac
     3481 agctaaatac atagaatccc cagcacatcc ataagtcagc tatttactat gctcgaattg
     3541 ctttacaccg cccttctcta ccttattcag ccgctgatct ggatacggct ctgggtgcgc
     3601 ggacgtaagg ctccggccta tcgaaaacgc tggggtgaac gttacggttt ttaccgccat
     3661 ccgctaaaac caggcggcat tatgctgcac tccgtctccg tcggtgaaac tctggcggcg
     3721 atcccgttgg tgcgcgcgct gcgtcatcgt tatcctgatt taccgattac cgttacaacc
     3781 atgacgccaa ccggttcgga gcgcgtacaa tcggctttcg ggaaggatgt tcagcacgtt
     3841 tatctgccgt atgacctgcc cgatgcactc aaccgtttcc tgaataaagt cgaccctaaa
     3901 ctggtgttga ttatggaaac cgaactatgg cctaacctga ttgcggcgct acataaacgt
     3961 aaaattccgc tggtgatcgc taacgcgcga ctctctgccc gctcggccgc aggttatgcc
     4021 aaactgggta aattcgtccg ccgcttgctg cgtcgtatta cgctgattgc tgcgcaaaat
     4081 gaagaagatg gtgcacgttt tgtggcgctg ggcgcaaaaa ataaccaggt aaccgttacc
     4141 ggtagcctga aattcgatat ttctgtaacg ccgcagttgg ctgctaaagc cgtgacgcta
     4201 cgccgccaat gggcaccaca ccgcccggta tggattgcca ccagcactca cgaaggtgaa
     4261 gagagcgtgg tcattgccgc acatcaggca ttgttacagc aattcccgaa tttattgctc
     4321 atcctggtac cccgtcatcc agaacgcttc ccggatgcga ttaaccttgt ccgccaggct
     4381 ggactaagct atatcacacg ctcttcaggg gaagtcccct ccaccagcac gcaggttgta
     4441 gttggcgata cgatgggcga gttgatgtta ctgtacggca ttgccgatct cgcctttgtt
     4501 ggcggttcac tggttgaacg tggtgggcat aatccgctgg aagctgccgc acacgctatt
     4561 ccggtattga tggggccgca tacttttaac tttaaagaca tttgcgcgcg gctggagcag
     4621 gcaagcgggc tgattaccgt taccgatgcc actacgcttg caaaagaggt gtcctcttta
     4681 ctcaccgacg ccgattaccg tagtttctat ggccgtcatg ccgttgaagt actgtatcaa
     4741 aaccagggcg cgctacagcg tctgcttcaa ctgctggaac cttacctgcc accgaaaacg
     4801 cattgaggtt gttatgcaaa aacgggcgat ttatccgggt actttcgatc ccattaccaa
     4861 tggtcatatc gatatcgtga cgcgcgccac gcaaatgttc gatcacgtta ttctggcgat
     4921 tgccgccagc cccagtaaaa aaccgatgtt taccctggaa gagcgtgtgg cgctggcaca
     4981 gcaggcaacc gcgcatctgg ggaacgtgga agtggtcggg tttagtgatt tgatggcgaa
     5041 cttcgcccgt aatcaacacg ctacggtgct gattcgtggc ctgcgtgcgg tggcggattt
     5101 tgaatatgaa atgcagctgg cgcatatgaa tcgccactta atgccggaac tggaaagtgt
     5161 gtttctgatg ccgtcgaaag agtggtcgtt tatctcttca tcgttggtga aagaggtggc
     5221 gcgccatcag ggcgatgtca cccatttcct gccggagaat gtccatcagg cgctgatggc
     5281 gaagttagcg tagcgtttat gccggatggt atgccatccg gcgcgcatga attacttctg
     5341 gcactgccga caataaaacg ttgcccgctg cgcatgttta gtcgccacaa tcggcgtacc
     5401 gcacacccga cacggctcgc cttttcgccc gtaaacctgc aattcctgag cgaaatagcc
     5461 cggtttacca tcactttgca gaaaatcttt cagcgttgta ccaccctgct caatcgaacg
     5521 cagcaacacc gctttaatca cccgagctaa caattcacac tctgccagcg acagtgatga
     5581 cgccagccga tccggatgga tccccgccgc aaacagtgat tcgctggcat agatattccc
     5641 tacccctacc accagcttgt tatccatcag ccacggttta atcgccgttt ttttcttcgc
     5701 gcacttctga tgcagatact caccattgaa atcgtcgcta agcggctccg gtccaagatg
     5761 ggtcagcaca ttatgccctt ccagctcttt ggtccacagc caggcaccaa agcggcgcgg
     5821 atcggtgtag cgcagcactt tgccgttgct catcaccaat tccacatggt catgcttttc
     5881 agggggaagt tcttctggaa ggatgcgcag gctgccagac atccctaaat gaatgataat
     5941 ccagccctca ggcagctcca gcagcagata tttagcccgc cgctgcacgc taagcactgg
     6001 ttggtcgctt aaacggtaga tctcttctga aaccggccag cgcaagcgtc cgttgcgcac
     6061 cactgcatga agaatggttg caccaacgag atgcggttct atgccgcggc ggctggtttc
     6121 aacttcgggt aattcaggca tagcatctcc aggaatgaac agatgcagtc aatatggggg
     6181 caagcagata acaaaaaacc ccgccggagc gaggtttttt gttacatcaa agcgagaatt
     6241 atttgatttt cgcttctttg tagatcacgt gctggcgaac aactggatcg aattttttca
     6301 gttccagttt ttccggctta gtacgtttgt tcttcgtagt ggtatagaag tgaccagtac
     6361 cagcagaaga aaccagcttg attttctcac gaataccttt agccatgatt tatttcctct
     6421 aagtacttag tacttttcgc cacgggcacg cagttcagcc agaactgtat cgatgccttt
     6481 tttatcgatt acacgcatac ctttagcaga tacgcgcagg gtgacaaaac gcttctcgct
     6541 ctcaacccag aaacggtgag agtgcaggtt cggcaggaaa cggcgtttag tcgcgttcag
     6601 tgcgtgggaa cggttgttac cggtcaccgg acgcttgcca gtaacttggc agactcggga
     6661 catgtctatt ctccaaaaat caaattagct cgagcttcgt atggggtatt ggcgcctcgt
     6721 caggctttac agcccggtca tcgcagttct atgtgaactc tcgattgcca ggcccaaatg
     6781 ccaaacccga gattctcaaa ggtggcgtag tatacgctga ctcagcgatg tgctcaagtc
     6841 ccgaacagac aaagatcccg aaggatcgcg catagcgggt taaatccagc cgcgttcggc
     6901 aaaagaaaca tactctccac gcccaatcac gatatggtcg agcacgcgta aatccatgaa
     6961 ctgacaactc tttattatcc gttcagtaat gagtttatcc gctttactgg gttcagcaca
     7021 acccgaaggg tgattatgtg caaggatcag cgccgaggcg tttattttta tcgcttcgcg
     7081 gataatttcc cgaggatgga cttcaacatg gtttagcgtg ccggaaaaaa gacggctatg
     7141 cgttataacc cggtgttggg agtcgagaaa gatcaccata aagatctccc gctcctcacc
     7201 cgtgagctgg ctttgtaaaa attccctcgt catctccggg ctgagtaaag ggctttcttc
     7261 acgcatccgc acgttgtagt aacgccgcgc cagttcagca atccccttta actgggcaaa
     7321 tttcgccacg ccaattccat gaacgccact aacttgttca tattcagagg ttaacaagcc
     7381 ataaagagag ccgaaattct ccagcatctc ttttgccagg gttaatacat ctttaccgcg
     7441 cgttccggta cgcagaaata gcgccagcag ctcgacatcc gttaaggcgc taataccaaa
     7501 cttcagcatt ttttcgcgcg gcatcaacag ctgtgaattg tttttcacct tcacctcctt
     7561 tgtggtgctc gcatcctgtc atagccgttt cgttaaatcg acggccagtt ttcaatcctg
     7621 gaaagcgcct cgcaaagtga atctcaggtg aaggcacgac aacaaaagta ttgtgataaa
     7681 atcgccaact tctggtgtca ccctacagga aaaatcatca tgagcctggc cggtaaaaaa
     7741 atcgttctcg gcgttagcgg cggtattgct gcctataaaa cccctgaact ggtgcgtcgt
     7801 ttgcgcgatc gcggggccga cgtccgcgta gccatgaccg aagcggcaaa agcctttatc
     7861 accccactta gcttgcaggc ggtttctggt tatcccgttt ccgacagtct gctggacccg
     7921 gcagccgaag ccgctatggg ccatattgag ctgggtaaat gggctgattt agtgattctc
     7981 gcccctgcca cggcagattt gattgcccgt attgctgccg gaatggcgaa tgacctggta
     8041 tcgacgattt gtctggctac acctgcgcct gtagccgtgc tccccgccat gaaccagcag
     8101 atgtaccgtg ccgctgccac gcagcataat ttagaggtgc ttgcttcccg tggtatgctc
     8161 atctgggggc cagacagtgg cagtcaggct tgtggtgata tcggtcctgg gcgaatgctc
     8221 gatccgttaa ccattgtgga tatggcggtg gcgcattttt cgcccgtcaa cgacctgaaa
     8281 catctgaaca ttatgattac cgccggcccg acgcgtgaac cgctcgatcc ggtgcgttat
     8341 atctctaatc acagctccgg caagatgggt tttgctatcg ccgccgccgc tgcccgtcgt
     8401 ggcgcgaacg tcacgctggt atcaggtccg gtttcactac cgacgccacc gtttgttaaa
     8461 cgtgttgatg tgatgactgc gctggaaatg gaagccgccg tgaatgcttc tgtacagcag
     8521 caaaatattt ttatcggttg cgccgccgtg gcggattatc gcgcagctac cgtggcccca
     8581 gagaaaatca aaaagcaggc cacgcagggt gatgaattaa caataaaaat ggttaaaaac
     8641 cccgatatcg tcgcaggcgt tgccgcacta aaagaccatc gaccctacgt cgttggattt
     8701 gccgccgaaa caaataatgt ggaagaatac gcccggcaaa aacgtatccg taaaaacctt
     8761 gatctgatct gcgcgaacga tgtttcccag ccaactcaag gatttaacag cgacaacaac
     8821 gcattacacc ttttctggca ggacggagat aaagtcttac cgcttgagcg caaagagctc
     8881 cttggccaat tattactcga cgagatcgtg acccgttatg atgaaaaaaa tcgacgttaa
     8941 gattctggac ccgcgcgttg ggaaggaatt tccgctcccg acttatgcca cctctggctc
     9001 tgccggactt gacctgcgtg tctgtctcga cgacgccgta gaactggctc cgggtgacac
     9061 tacgctggtt ccgaccgggc tggcgattca tattgccgat ccttcactgg cggcaatgat
     9121 gctgccgcgc tccggattgg gacataagca cggtatcgtg cttggtaacc tggtaggatt
     9181 gatcgattcc gactatcagg gccagttgat gatttccgtg tggaaccgtg gtcaggacag
     9241 cttcaccatt caacctggcg aacgcatcgc ccagatgatt tttgttccgg tagtacaggc
     9301 tgaatttaat ctggtggaag atttcgacgc caccgaccgc ggtgaaggcg gctttggtca
     9361 ctctggtcgt cagtaacaca tacgcatccg aataacgtca taacatagcc gcaaacattt
     9421 cgtttgcggt catagcgtgg gtgccgcctg gcaagtgctt attttcaggg gtattttgta
     9481 acatggcaga aaaacaaact gcgaaaagga accgtcgcga ggaaatactt cagtctctgg
     9541 cgctgatgct ggaatccagc gatggaagcc aacgtatcac gacggcaaaa ctggccgcct
     9601 ctgtcggcgt ttccgaagcg gcactgtatc gccacttccc cagtaagacc cgcatgttcg
     9661 atagcctgat tgagtttatc gaagatagcc tgattactcg catcaatctg attctgaaag
     9721 atgagaaaga caccacagcg cgcctgcgtc tgattgtgtt gctgcttctc ggttttggtg
     9781 agcgtaatcc tggcctgacc cgcatcctca ctggtcatgc gctaatgttt gaacaggatc
     9841 gcctgcaagg gcgcatcaac cagctgttcg agcgtattga agcgcagctg cgtcaggtat
     9901 tgcgtgaaaa gagaatgcgt gagggtgaag gttacaccac cgatgaaacc ctgctggcaa
     9961 gccagatcct ggccttctgt gaaggtatgc tgtcacgttt tgtccgcagc gaatttaaat
    10021 accgcccgac ggatgatttt gacgcccgct ggccgctaat tgcggcacag ttgcagtaat
    10081 atgacgccgg atgacttttc atccggcgag tttctttaaa cgccaaactc ttcgcgatag
    10141 gccttaaccg ccgccagatg ttccgccatt tccggcttct cttccaggta agcaatcagg
    10201 tctttcaggg tgatgataga gatcactttg cagttgtaat cacgctcaac ttcctgaatc
    10261 gccgaaatct cgccgcgccc ccgttcctga cgatcaagcg aaatcaacac gccagcaagc
    10321 gtcgcgccat tagcctgaat aatctccatc gattcgcgaa tcgccgttcc ggcggtgatc
    10381 acatcatcta ccagcattac gcgtccttgt aacgcgctac caaccagatt gccgccttca
    10441 ccgtggtctt ttgcctcttt gcggttaaag cagtacggca ggtcaaggtc atgatgctcc
    10501 gccagcgcca cggcggtagt ggtggcaatc gggatccctt tgtaagcagg gccaaacagc
    10561 agatcgaact caaggccgga atccaccaac gcttcagcgt aaaaacggcc taacagtgcc
    10621 agatcgcgcc cggtattaaa cagcccggcg ttgaagaaat aggggctttt gcgcccggac
    10681 ttcaacgtaa actcgccaaa ctttaacacc tgcttgccaa gcgcaaattc aataaactgg
    10741 cgctgatatg gtttcatgcc ttcgctcctc atcttacttt tctacagaca aaaaaaaggc
    10801 gactcatcag tcgccttaaa aatcagtttg ccagcgccgc cttctgcgtc gctacaatgg
    10861 attcgattcc ccctcgggcc agagccaaca aggtgagtag ctcttcatgg gtgaacggct
    10921 cgccttctgc cgtcccctgc acttcaatga tgcgcccgtc ttcggtcatc actacgttca
    10981 tgtcggtctc tgcggcagag tcttcaacgt attccagatc gcaaaccgct tcgccgttca
    11041 caattccgac agaaactgcg gctaccatcc ctttcatcgg attggttttc agcttgccgt
    11101 tttccaccag cttctgtagc gcatctgcca gcgccacgca ggcacccgta atcgacgcgg
    11161 tacgcgtgcc accatcagcc tgaagcacgt cgcagtccag cgtaatggtg aactcaccca
    11221 gcgctttcaa atctactgcc gcgcgaagag cacgggcgat cagacgctgg atttccattg
    11281 tgcgtccacc ctgcttacct ttcgccgctt cacgagcgtt acgggtgtgg gtagaacgtg
    11341 gcagcatgcc gtactctgcg gtgatccagc cctggccctg acctttcagg aagcgcggca
    11401 cgccttcttc aatagaggcg gtacacaaca ctttggtatc gccaaattcg accagcaccg
    11461 agccttctgc atgttttgta tagttacgag tcagggtaac gggacgcacc tgattattgc
    11521 tacggcctgc tggacgcata ttgaaatctc cggcttgaaa caaatgtggc tgcgcattat
    11581 acggacttcc ggcggttatt cctatcctga caaggcatcg atggctataa tccttccacc
    11641 tctcctttta taaacaggaa cgtctatgat ccgcagtatg accgcctacg cccggcgtga
    11701 aatcaagggt gaatggggga gcgcaacctg ggaaatgcgc tcggtaaacc agcgttatct
    11761 ggaaacttac tttcgtctgc cggagcagtt ccgtagcctt gaacctgtcg ttcgcgagcg
    11821 tattcgttct cgcctgacgc gcggtaaagt ggaatgtacc ctgcgctatg agccagatgt
    11881 tagcgcgcaa ggtgagctga tcctcaacga aaaactggct aaacagctgg taactgccgc
    11941 gaactgggta aaaatgcaga gtgacgaagg ggaaatcaac ccggttgata ttctacgctg
    12001 gccgggcgtg atggcagccc aggagcagga tcttgacgcc attgccgctg aaattctcgc
    12061 ggcgctggat ggtacgctgg acgactttat tgtcgcgcgc gaaaccgaag gtcaggcact
    12121 gaaagcattg atcgagcagc gtctggaagg cgtcaccgcc gaagtggtca aagtccgcgc
    12181 ccatatgccg gaaatcctgc aatggcagcg tgagcgtctg gtcgcgaagc tggaagatgc
    12241 tcaggttcag ttggaaaaca accgtctgga gcaggagctg gttctgctgg cacaacgaat
    12301 tgacgttgcc gaagaactgg accgcctgga agcgcatgtc aaagagacct acaacattct
    12361 gaagaaaaaa gaagccgttg gtcgtcgtct ggactttatg atgcaggaat tcaaccgcga
    12421 gtcgaacact cttgcgtcga agtctatcaa tgccgaagtg acaaactccg cgattgagct
    12481 gaaagtgttg attgagcaga tgcgcgagca gattcagaac attgaataac tcgtaacgcc
    12541 aattcttact tttcagcctt cacaaatgcc gcccactcaa acagagcggc atttttcttc
    12601 cccgcaactt caattctgtt ttgcgtgcct gctccagatt ttgcgatgtt tttttgccca
    12661 gcacactgag aacgtgagat actcacaact gtatataaat acagttacag atttactttc
    12721 tttgcaatcg atatcacatg gagtgggcaa tgaacgaaca tcatcaacct tttgaagaaa
    12781 tacggcatta tggcactgaa gggcaagaat tttggtcagc tagagaattg gcaccgttac
    12841 tggattatcg ggactggcgc aattttcaaa aggtactggc ccgcgcgact caagcgtgcg
    12901 aagccagcaa tcaagctgca tctgaccatt tcgttgaaac caccaaaatg gttgtattag
    12961 gttcaggggc tcaacgagaa cttgaagatg ttcatctctc ccgctatgcc tgttacctgg
    13021 tagtacaaaa cggcgaccct gcgaaaccgg tcattgcggc agggcagact tattttgcta
    13081 tccagacccg acggcaggag cttgctgacg atgaagcatt taagcaactt cgtgaagacg
    13141 aaaagcgtct gtttctgaga aatgagttga aagaacataa caaacaattg gttgaggcag
    13201 cacagtaagc tggggtagcg acagctactg atttcgccat atttcagaat catggttacc
    13261 aggggctgta tggtggatta gatcagaaag ccatccacca actgaagggg ctgaaaaaga
    13321 gtcagaagat cctggatcat atgggttcaa cagaactggc ggctaatctc tttcgagcta
    13381 cccaaacaga agaaaaactc aagcgggatg gcgtgaattc aaaacagcaa gctaatacca
    13441 cacactttga cgtgggtagc aaggtgaggc aaaccattca ggaacttggc ggaaccatgc
    13501 ctgaggagtt gccgaccccg caggtcagca tcaagcagtt ggaaaacagt gtaaaaatta
    13561 cagagaagaa atagcagaaa ctaaaaactc tttttgttga ttgagatacc cgatgcgtaa
    13621 gccaaagtcc aggtgcggtg aacacaatgg ctaaacattg cacctttctt ttccacccct
    13681 caattttaac ctattttttc ttatgcattt tctcagacaa gaagtcagaa gaatgcatct
    13741 acgctacaga aaatagcgat ttcacataac tacaagttat caatttcctc tcaccttaaa
    13801 aaatctcaat cgtgacaata cgcacaaatc gctaccctgc cagacagatt tttagggaga
    13861 gaaccatgct gttacacatt ttgtatttgg ttggcattac tgccgaagcc atgacggggg
    13921 ctctggcggc cgggcgacgc cgcatggata catttggcgt aattattatt gcgaccgcca
    13981 ccgcaattgg cggagggtca gtgcgcgata ttctgctggg ccactatccg ctcggctggg
    14041 tcaaacaccc ggaatatgtg attatcgtcg ctaccgccgc agtactcacc actatcgttg
    14101 ctcctgtaat gccttacctg cgcaaagtgt ttctggtgct cgatgcgctt ggactggtgg
    14161 tcttttctat catcggcgca caggttgcac tggatatggg gcacggccca attattgccg
    14221 ttgtcgcggc ggtaaccacc ggcgtgtttg gcggcgtttt gcgcgatatg ttctgtaaac
    14281 gtatcccact ggtattccag aaagagttgt atgccggtgt ctcatttgcc tccgccgtgc
    14341 tgtacatcgc gctgcaacac tatgtttcta accatgatgt ggtaattatc tccaccctgg
    14401 tattcggctt ttttgcccgc ttactggcgc tacgccttaa gctgggatta ccggtctttt
    14461 actacagcca cgaaggacac taaggttcaa aacctgtgat ctgctgggca gccagccaac
    14521 tgcccagctt cttgatttgc gcattttcct tccattcagt aacctgtctg gcgcgccccg
    14581 atccagtccc cggcagctgc tgccagaact gctccgtgct aaataaaagt tgcgaccagg
    14641 accgttcatc actggcatta agcgccgccc gggttagcgg tattcccatt gccatcaccc
    14701 agcgagtaaa aggctgctta cgagccagat taaaccgatg ccatagctgc gcacttttac
    14761 ttttcgcgat ccccggcgtg ttctgtaatt gctctggcgt taataaaagc caggaaaaga
    14821 tatgctcaaa gcgatgagtc tgatgcagcg cgcgccagcc ggcctcacca ataccatcca
    14881 gccccagaac ctgttttgac cccagccaga ctaagcgtga aatgaactgt tcctgacaaa
    14941 catcagaagc aaagtagcag gtcaacgagt taaagcggtt ttctggtggt gtcggttttg
    15001 tacgttctgc accgcgccag accacatcat caatgcgagg aataccctga ccggcaaggc
    15061 tgacgaggat ctgatcacca ggcgcaatat cccactcctg ccagcgcctg acggaaccaa
    15121 tattcacccg ctggactttt ttatcatcca gcatgacagg tgcgagtgac gcaaccaccg
    15181 atattttacc gctcttaccc accgcaaact gaatcgcctt cacttcggca acctgagcta
    15241 caggttgata tttccaggcc accagccatt ctgcctggcc tggtagccaa tggcgggatt
    15301 cgggttcttt cgcccctcgc acaaccacgc catcggtgac gaagggtaat ttcgctttcc
    15361 accactcatt gcgtacgcgc gcaacctcat cagcattttt aaccgcacgg gtatacctct
    15421 gcgttagagt aaaacctgcg gtagccagct cctttaaacg atcggtcatt aactgcggtc
    15481 catccggcca tgcccagaca aaaacgccca gagaattcag cgtgtcgcta tcgtcctggc
    15541 gcatcatcag gccagcaact tttgcgcggg catttattcc ccccatttgt tgttggatat
    15601 gcccctcgcg ctggagaaat atttccccct gaagcgtact gttggctaaa ggcccgctaa
    15661 cggtttgcgg cacagcggaa attaagctaa ctttctgcgt ccagtcctcg cctttcaggc
    15721 cattaccgcg actgattgct ttgttcagtt tcccgtcccg ataaaccagg gttaccgcaa
    15781 cgccatcaac ttttggctgc acccaaagat cgctacgttc tcgcatccac agacttaatg
    15841 cgtttttatc cgccattttg cgtacacccg tatgggcaac cggatgcata accgcaccat
    15901 ttaaaggcgg catcatcacg tcgcggggct cgctcacaaa gcagcgttgc cactgcgtaa
    15961 gacgggcgct taactgatcg taaacaccgt cttccacctc actttttcct tccttccagt
    16021 agtcatcgtc ccactgtttt atttgctgtt gcaggcgtga aatttcttcc tgtgctctgg
    16081 ctggcgacca ggccggacag accgcccaca cagatgattg ccagcacaag atacttatta
    16141 atatcgccat ccatactttc atcttcacct ccgctgtagt caggctggca gatatacaac
    16201 gtggtgaagg caaagccgag tggcaaaaac ggagtctgcg aggacgcttc ctgagaatcg
    16261 tctttattgc agtaaatcac aggcaaatgc ggaaacagct acgcaaaacg caacaacttt
    16321 gcgcaaaaag tgtgagcaag ggctacgtca catggccgcg ccgtgtataa taagctcgta
    16381 tgtaggcttt atttcgctaa tcacatacga aagatactca tggctcaagg cacgctttat
    16441 attgtttctg cccccagtgg cgcgggtaaa tccagcctga ttcaggcttt attaaaaacc
    16501 caaccgttgt atgacaccca ggtttctgtt tcacacacca cacgccaacc gcgtcctggt
    16561 gaagtccacg gtgaacatta tttctttgtt aatcatgatg aatttaaaga aatgattagc
    16621 agagatgcgt tcctcgaaca cgcagaagtt tttggtaatt actatggcac ttcgcgtgag
    16681 gccattgagc aagtactggc gaccggtgtc gatgtttttc tcgatatcga ctggcagggc
    16741 gcgcagcaaa ttcgccagaa gatgccgcac gcgcggagta tctttatttt accgccgtcc
    16801 aaaattgaac tggaccgccg tctacgcggt cgcggtcagg acagcgaaga ggtcattgca
    16861 aagcgtatgg cgcaagctgt tgcagaaatg agccattacg ccgaatatga ttatctgatt
    16921 gtgaatgatg acttcgatac cgcgttgacc gatttgaaga ccattattcg cgccgaacgt
    16981 ctgcgcatga gccgccaaaa gcagcgtcat gacgctttaa tcagcaaatt gttggcagac
    17041 tgaacctgat ttcagtatca tgcccagtca tttcttcacc tgtggagctt tttaagtatg
    17101 gcacgcgtaa ctgttcagga cgctgtagag aaaattggta accgttttga cctggtactg
    17161 gtcgccgcgc gtcgcgctcg tcagatgcag gtaggcggaa aggatccgct ggtaccggaa
    17221 gaaaacgata aaaccactgt aatcgcgctg cgcgaaatcg aagaaggtct gatcaacaac
    17281 cagatcctcg acgttcgcga acgccaggaa cagcaagagc aggaagccgc tgaattacaa
    17341 gccgttaccg ctattgctga aggtcgtcgt taatcacaaa gcgggtcgcc cttgtatctg
    17401 tttgaaagcc tgaatcaact gattcaaacc tacctgccgg aagaccaaat caagcgtctg
    17461 cggcaggcgt atctcgttgc acgtgatgct cacgaggggc aaacacgttc aagcggtgaa
    17521 ccctatatca cgcacccggt agcggttgcc tgcattctgg ccgagatgaa actcgactat
    17581 gaaacgctga tggcggcgct gctgcatgac gtgattgaag atactcccgc cacctaccag
    17641 gatatggaac agctttttgg taaaagcgtc gccgagctgg tagagggggt gtcgaaactt
    17701 gataaactca agttccgcga taagaaagag gcgcaggccg aaaactttcg caagatgatt
    17761 atggcgatgg tgcaggatat ccgcgtcatc ctcatcaaac ttgccgaccg tacccacaac
    17821 atgcgcacgc tgggctcact tcgcccggac aaacgtcgcc gcatcgcccg tgaaactctc
    17881 gaaatttata gcccgctggc gcaccgttta ggtatccacc acattaaaac cgaactcgaa
    17941 gagctgggtt ttgaggcgct gtatcccaat cgttaccgcg taattaaaga agtggtgaaa
    18001 gccgcgcgcg gcaaccgtaa agagatgatc caaaaaatcc tctctgaaat cgaagggcgt
    18061 ttgcaggaag cgggaatacc gtgccgcgtc agtggtcgcg aaaagcatct ttattcgatt
    18121 tactgcaaaa tggtgctcaa agagcagcgt tttcactcaa tcatggacat ctacgctttc
    18181 cgcgtgatcg tcaatgattc tgacacctgt tatcgcgtgc tgggccagat gcacagcctg
    18241 tacaagccgc gtccgggtcg cgtgaaagac tatatcgcca ttcctaaagc gaacggctat
    18301 cagtcgttgc acacctcgat gattggcccg cacggcgtgc cggttgaggt ccagatccgt
    18361 accgaagata tggatcagat ggcggagatg ggtgttgccg cgcactgggc ttataaagag
    18421 cacggcgaaa ccagtactac cgcacaaatc cgcgcccagc gctggatgca aagcctgctg
    18481 gagctgcaac agagcgccgg tagttcgttt gaatttatcg agagcgttaa atccgatctc
    18541 ttcccggatg agatttacgt tttcacaccg gaagggcgca ttgtcgagct gcctgccggt
    18601 gcaacgcccg tcgacttcgc ttatgcagtg cataccgata tcggccatgc ctgcgtgggc
    18661 gcacgcgtcg accgccagcc ttacccgctg tcgcagccgc ttactagcgg tcagaccgtt
    18721 gaaatcatta ccgctccggg cgctcgcccg aatgccgctt ggctgaactt tgtcgttagc
    18781 tcgaaagcgc gcgccaaaat tcgtcagttg ctgaaaaacc tcaagcgtga tgattctgta
    18841 agcctgggcc gtcgtctgct caaccatgct ttgggtggta gccgtaagct caatgaaatc
    18901 ccgcaggaaa atattcagcg cgagctggat cgcatgaagc tggcaacgct tgacgatctg
    18961 ctggcagaaa tcggacttgg taacgcaatg agcgtggtgg tcgcgaaaaa tctgcaacat
    19021 ggggacgcct ccattccacc ggcaacccaa agccacggac atctgcccat taaaggtgcc
    19081 gatggcgtgc tgatcacctt tgcgaaatgc tgccgcccta ttcctggcga cccgattatc
    19141 gcccacgtca gccccggtaa aggtctggtg atccaccatg aatcctgccg taatatccgt
    19201 ggctaccaga aagagccaga gaagtttatg gctgtggaat gggataaaga gacggcgcag
    19261 gagttcatca ccgaaatcaa ggtggagatg ttcaatcatc agggcgcgct ggcaaacctg
    19321 acggcggcaa ttaacaccac gacttcgaat attcaaagtt tgaatacgga agagaaagat
    19381 ggtcgcgtct acagcgcctt tattcgtctg accgcccgtg accgtgtgca tctggcgaat
    19441 atcatgcgca aaatccgcgt gatgccagac gtgattaaag tcacccgaaa ccgaaattaa
    19501 tgttttatga acccaacacg ttatgcacgc atctgcgaaa tgctcgccag gcggcagcct
    19561 gatctgaccg tctgcatgga gcaggtccac aaacctcata acgtttctgc gattattcgt
    19621 accgcagatg ccgttggcgt acatgaagtt cacgccgtct ggcctggtag ccgcatgcgc
    19681 accatggctt cggcagcggc gggtagtaac agctgggtac aggtgaaaac acaccgcacc
    19741 attggcgatg ccgtcgctca tctcaaaggc cagggcatgc agattctggc aacccatctt
    19801 tctgataacg ctgtcgattt ccgcgaaatt gattacactc gcccgacctg cattttgatg
    19861 ggacaggaga aaacgggcat cacgcaggaa gcattggccc tggcggatca ggacatcatc
    19921 attccgatga tcggcatggt gcagtcgctg aatgtttccg ttgcctcagc cctcattctt
    19981 tacgaatccc agcgtcagcg gcaaaatgca ggcatgtacc tgcgtgaaaa cagcatgttg
    20041 ccggaagcag agcaacaacg cctgttgttt gaaggcggct atccggtgct ggcgaaagtc
    20101 gcaaaacgca aaggcctgcc ttatccccac gtcaatcagc aaggcgagat cgaagctgat
    20161 gccgactggt gggctactat gcaggctgca gggtaagtgc catgaaaggt cgcctgttag
    20221 atgctgtccc actcagttcc ctaacgggcg ttggcgcagc acttagtaac aaactggcga
    20281 aaatcaacct gcataccgtg caggatctac tcttacacct tcccctgcgc tacgaagatc
    20341 gcacccatct ctaccccatc ggagaactac tgccgggcgt ttatgccacg gtggaaggcg
    20401 aagtgctgaa ctgcaatatc tccttcggcg gtcggcggat gatgacctgc cagatcagcg
    20461 acggttccgg catcctcacc atgcgctttt tcaatttcag cgcggcaatg aaaaatagcc
    20521 tggcgacggg ccgccgtgta ctggcttatg gcgaagcaaa gcgcggtaaa tatggtgcgg
    20581 agatgatcca cccggaatac cgcgtgcagg gcgatctcag cacgccagaa ttacaggaaa
    20641 cgctcacgcc ggtttatcca acaacggaag gcgtaaagca ggccacgctg cgtaaattaa
    20701 ccgaccaggc gctggatctg ctcgacacct gcgccattga agaactcctg ccgccggaac
    20761 tgtcacaagg aatgatgacg ctaccggaag cgttgcgcac tttgcaccgc ccgccaccga
    20821 cgctacagct tagcgatctg gaaaccgggc agcatccggc gcaacgtcgt ctgattctgg
    20881 aagaactgct ggcgcacaac ctcagcatgt tagccttacg tgccggagca cagcgttttc
    20941 atgcccagcc gctgagcgcc aatgacacgc tgaaaaataa actcctcgcc gccttaccgt
    21001 tcaagcaaac gggcgcacag gcacgcgtag tggcggagat cgagcgcgat atggcgctgg
    21061 atgtgccgat gatgcgtctg gtgcagggcg atgtaggttc cggtaaaacg ctggtcgccg
    21121 ccctcgccgc gttgcgtgcg attgcccacg gcaaacaggt agcattgatg gcaccaaccg
    21181 aattactcgc cgagcagcac gccaataact tccgcaactg gtttgcaccg ctcggtatcg
    21241 aagtgggctg gctcgccggt aagcagaaag gtaaagcacg gctggcacag caggaagcca
    21301 tcgccagcgg tcaggtgcag atgattgtcg gtacacacgc catcttccag gaacaggtgc
    21361 agtttaacgg cctggcgctg gtgattatcg acgaacagca tcgttttggc gtacatcagc
    21421 gtctggcatt gtgggagaaa ggccagcagc agggcttcca tccgcatcag ttgatcatga
    21481 ccgccacgcc gatcccccgc acgctggcaa tgactgcgta tgccgatctc gatacctcgg
    21541 tgatagatga gctgccgcca ggccgcacgc cagtgactac ggtcgctatt cctgataccc
    21601 gccgtaccga catcattgac cgcgtgcgcc acgcctgcat aactgaaggt cgtcaggcat
    21661 actgggtttg tacgttgatt gaagagtcgg aattgctgga agcgcaggcg gcggaagcta
    21721 cctgggaaga gttgaaactg gcgctaccag agttgaacgt tggcctggta cacgggcgga
    21781 tgaaacctgc cgagaaacag gcggtgatgg cgtcgtttaa acaaggtgag ctacacctgc
    21841 tggttgccac aaccgttatt gaagtcggcg ttgatgtgcc taacgccagt ctgatgatta
    21901 tcgaaaaccc ggagcgtctg ggtctggcgc agttacacca gcttcgcggg cgtgtaggtc
    21961 gtggtgcggt ggcttctcac tgcgtgctgc tctacaaaac gccgctctcc aaaaccgcgc
    22021 aaattcggct gcaagtgctg cgcgacagca acgacggttt tgtgattgca cagaaagact
    22081 tagagattcg cggaccgggt gaactgttag gtacgcgtca gacgggtaat gctgagttta
    22141 aagtggcgga tttactgcgc gatcaggcga tgatcccgga agttcagcgc ctggcgcgac
    22201 atattcacga acgttaccca caacaagcaa aagccctgat agaacgctgg atgccggaga
    22261 cggaacgtta ctccaacgca tgaccagact catcacaaga caagtcacgc agtaaatctt
    22321 caatctggat agtgaggata tccattgcct catacgcatc ctgtgcaatt cgcgccgcca
    22381 ttgcgccttc cggttcacca cgcagaattt cagccgctgc ctgtacgcca gccacaatca
    22441 tttcaggtgt taacatttgg cgaagaaaag cgcgattatc agaggaccag ccatctttat
    22501 ggcctaatgg atgcccccag cctatccatt cttgcgacca taacggattg gcttctatgg
    22561 gataaattag atgcgcggca tactgaatag cacacaccgc ttttcctggc gtatccagcg
    22621 cccaccagcg cgaccagaga gaacgaatta acggcgcggc cccacccaga gtattgaaca
    22681 ccgccagcca gcaaagaacg ttattgaaac cacgctcgtt atccatacgc tgcaacgcgg
    22741 tgtccagtaa aaattgccgt acctgctggc gttgggaagc attcatcatc tcctgccaga
    22801 gatagggccg acacaatgcc ttcattaagg attcttcgaa gtgatcacca taaccgccag
    22861 ctaaaacggt ttcatgccat tgcgccaggc agagcggaaa cagatagcga aacaactcta
    22921 tttgcatcgg ttcgttataa acgagattga gtacatagta agcactcaaa tcccattcgc
    22981 tgatctgctg ccactcttta gccgccagcg ccttgagttc ggcatctgcg taatcaaatt
    23041 ccgtttccca tacacagagc actggcggct catcaccaaa aatatggcga cagtgttcac
    23101 gtagcgtttc cggttccttc cgacgctttt tcatttttaa ccggcaaaaa tcggcaacat
    23161 taaatacagc ttaatcacca gcgcattgac gatatcgata aagaacgcac cgaccatcgg
    23221 caccaccaaa aacgccatgt gcgacgggcc aaagcgttca gtgatcgcct gcatgttggc
    23281 gattgccgtt ggcgttgcac cgaggccaaa accacagtga cccgcagcca gcactgccgc
    23341 atcgtagttt ttgcccatca tgcgccaggt aacgaagatg gcatacaacg ccatgaagat
    23401 ggtctgtacc accagaatcg ccagcatcgg cagcgccagc gaagccagct cccacagttt
    23461 cagccccatc agcgccatcg ccaggaacaa cgacaggctt acgttaccca gcacggatac
    23521 cgcacgctca aagacgcggt aaaagcccat cattgacaga ccgttgctca gaatcacgcc
    23581 aacaaacagt acacagacga aggtcggcag ttcaaaagca gtgccagcca aaagttgcgc
    23641 aacaattttc cccaccgtca ggcagatagc aatcagcgcg atagtttcaa tcagcaccag
    23701 cgaggtgatc atgcgtccca catccggctt ttcaaacgcc gtcgggactt cctggtcatc
    23761 cggaataccg ttcggcgtgg tggagtgttt caccagatag cgcgccaccg gaccgccaat
    23821 caagccgccc agcaccagac cgaacgttgc acaggccatc gccacttccg tcgcattggt
    23881 gaagccataa cgttcaatga acaatttact ccacgcagcg cccgtaccgt gaccgccgga
    23941 aagcgtaata gaaccggcca acagccccat cagcggatca agccctaaca ggctagccat
    24001 accaatgcca atggcatttt gcatcaccaa cagaccaaca accacaatca agaagatgcc
    24061 aaccacacgc ccaccggcac gcaaactggc aatgttggcg ttcaggccaa tggtggcgaa
    24121 gaaagccagc attaacggat cgcgcaggga catatcaaag ttgacttccc agcccatgct
    24181 ttttttcagt actagtagcg ccagcgccac caacaaacca cccgcaacag gttccggtat
    24241 ggtgtatttc ttcaaaaagg agacggaatg gaccaactta cgcccgagca gcaacgtcag
    24301 cgttgcggca acaagcgttg ctaaagtatc gagatgaaac atagttactc ctttgtatcc
    24361 gcatcactct ttcatactcg tcatacttca tcgcgcagtg gcaacttcat gaactatgac
    24421 gggtatcgag ttatgctttc ctgggtcaaa ttctcagctg ttaatgaaca aatggcatgg
    24481 attttaagca gaaaaatacc aaaagttata taaaaaagtg catttatctc atttaaatat
    24541 ttagatgagg atgtggcaaa cgtttgcttt tctctttcgg tcagctaaaa tgcccgcttt
    24601 gctaccacgg gattgttttc gatgtctgtt tccaccctcg agtcagaaaa tgcgcaaccg
    24661 gttgcgcaga ctcaaaacag cgaactgatt taccgtcttg aagatcgtcc gccgcttcct
    24721 caaaccctgt ttgccgcctg tcagcatctg ctggcgatgt tcgttgcggt gatcacgcca
    24781 gcgctattaa tctgccaggc gctgggttta ccggcacaag acacgcaaca cattattagt
    24841 atgtcgctgt ttgcctccgg tgtggcatcg attattcaaa ttaaggcctg gggtccggtt
    24901 ggctccgggc tgttgtctat tcagggcacc agcttcaact ttgttgcccc gctgattatg
    24961 ggcggtaccg cgctgaaaac cggtggtgct gatgttccta ccatgatggc ggctttgttc
    25021 ggcacgttga tgctggcaag ttgcaccgag atggtgatct cccgcgttct gcatctggcg
    25081 cgccgcatta ttacgccgct ggtttctggc gttgtggtga tgattatcgg cctgtcgcta
    25141 attcaggttg ggttaacgtc cattggcggc ggttacgcag ccatgagcga taacaccttc
    25201 ggcgcaccga aaaatctgct gctggcaggc gtggtcttag ccttaattat cctgcttaac
    25261 cgtcaacgta acccttactt acgcgtggcc tcactggtga ttgcgatggc ggccggatat
    25321 gcgctggcgt ggtttatggg catgttgcca gaaagcaacg aaccgatgac gcaagaactg
    25381 attatggtgc caacgccgct ctattacggt cttggcattg aatggagtct gctgctgccg
    25441 ctgatgctgg tctttatgat cacttcgctg gaaaccattg gcgatatcac ggcgacctct
    25501 gacgtttccg aacagccagt gtccggtccg ctgtacatga aacgcctgaa aggcggcgtg
    25561 ctggcaaacg gcctgaactc gtttgtttcg gcggtgttta acaccttccc gaactcctgc
    25621 ttcgggcaaa acaacggagt gatccagttg actggtgttg ccagccgcta tgtcggtttt
    25681 gtcgtcgcgc tgatgttgat cgtgctgggt ctgttcccgg cagtgagcgg ttttgtacaa
    25741 cacattccag aaccggttct gggcggcgca acgcttgtaa tgtttggcac catcgccgcc
    25801 tccggtgtgc gtatcgtttc tcgtgagccg ctgaaccgtc gggcgattct gattatcgcg
    25861 ctgtcgctgg cggttggtct gggcgtgtct cagcagccgc tgattttgca gtttgcccct
    25921 gaatggctga aaaacctgct ctcctccggg atcgccgcgg gcggtattac tgccatcgtg
    25981 ctgaatctga ttttcccacc agaaaaacag taattcactg gcggcggtaa gataattacc
    26041 gccgcagtct cacctctttc accattcccg ccttgaggat tgcgcgtaaa tcgtgcataa
    26101 ctcccttatg tgcatttcac gggatggaag accatgaaat ttattgggaa gctgcttctc
    26161 tacattctca tcgctctgtt agtggtgatc gctggcctct attttcttct gcaaacccgc
    26221 tggggagcag aacatatcag cgcatgggtt tccgagaata gcgactatca tctggccttc
    26281 ggggcgatgg atcaccgttt ttccgcgcca tctcatatcg tgctggagaa cgtcacgttt
    26341 ggtcgtgatg gtcagcccgc gaccctggtg gcaaaaagtg tcgacattgc gctaagcagt
    26401 cggcaactga ccgaaccacg ccatgtcgat accatcctgc tggaaaacgg gacgctgaat
    26461 ctcaccgacc agaccgcgcc gctaccgttc aaagccgatc gtctgcaact gcgtgatatg
    26521 gcgtttaata gcccgaatag cgaatggaaa ctgagcgcgc agcgggtaaa tggcggcgtg
    26581 gttccgtggt caccagaagc cggtaaagtg ctgggtacga aggcgcagat tcagtttagt
    26641 gccggatcgc tttcgctcaa tgatgttcct gccaccaatg tactgattga aggcagtatt
    26701 gataacgatc gcgttacgct gactaacctg ggtgccgaca tcgcccgcgg gacattaacc
    26761 ggaaacgcgc agcgtaacgc cgacggcagc tggcaagtgg aaaatctgcg catggcggat
    26821 atccgtctac aaagcgaaaa atcgctaacc gacttctttg cgccattacg ctctgtcccg
    26881 tcgttgcaga ttggtcgcct ggaagtgatc gatgctcgtt tgcaaggtcc ggactgggcg
    26941 gtgaccgacc tcgatctcag cttgcgcaac atgaccttca gtaaagatga ctggcagaca
    27001 caagaaggca aactgtcgat gaacgccagc gagttcattt atggttcgct gcatttattt
    27061 gacccgatta taaacgcgga attttccccg cagggcgtag cgctgcgcca gttcaccagc
    27121 cgctgggaag ggggtatggt cagaacgtca gggaactggc tgcgtgacgg gaaaacgttg
    27181 atccttgatg atgcggcaat tgccgggctg gaatatacct tgccgaaaaa ctggcaacag
    27241 ttgtggatgg aaacgacacc cggttggtta aacagcctgc aactgaagag atttagcgcc
    27301 agccgcaatc tgatcattga tatcgaccct gacttcccgt ggcagctcac cgcgctcgat
    27361 ggttacggtg ccaacctgac gctggttacc gatcataaat ggggcgtctg gagtggctcg
    27421 gcgaatctga atgccgccgc cgcgacattc aatcgtgttg atgttcgtcg cccgtcgctg
    27481 gcgctgaccg ccaacagcag cacggtgaat atcagcgaac tgagtgcatt tactgaaaaa
    27541 ggcattctgg aagccaccgc cagtgtttca caaacgccac aacgtcagac acatatcagc
    27601 ctgaatggac gcggtgtgcc ggtgaatatt ttgcaacagt ggggatggcc taaattaccg
    27661 ttgactggcg acggcaatat tcagcttacc gccagtggcg atattcaggc caatgtcccg
    27721 ttgaaaccta cggttatcgg gcaattgcat gccgtgaacg ccgcaaagca gcaagtgact
    27781 caaaccatga atgctggcat cgtttccagc ggtgaagtta catcgacgga gccggtgcgg
    27841 taaacatcaa tctcgccggg tacgactcag acgtacccgg cattccatca atagattaca
    27901 acgtaattgt cagcgcattc ccttgaggct tcaccaccag cccctgctca ctttcagcct
    27961 gcgaaccgtc ttgcagacca tttactttca caacattgcg caggcacagc gtccagttct
    28021 tcgcctcgcc cgcaccagtc acagtaatcg tgttgccagt acgtgctgct tttaaagtaa
    28081 agatcaccga tccgtcagta gcgggcactt cacagacggc ttcatgcccg tcttgcagat
    28141 taaagaggtg gaatgccgtg ccttcgtgcc acacgtaatc gggacgttga tcgttgttgc
    28201 ccagcgccag tagagtgtta tcacgcacat aaacgggcag actcaggaag ccgtgctgct
    28261 gtttatgcca gcgactaccg tcgagttcat cgttgtgcca caggtgtgtc cagcgacctt
    28321 ccggcaggta gaactgcaca tcgcccgctt cagtgaacac cggcgcaacc atcacgttgt
    28381 cgcctaacat gtattgacgg tcaaggtaat cacaagccgg atcgtccggg aactccatca
    28441 tcatggcccg catcatcggc gtaccccgcg cgttcgcacg cgcagcttca cgatacagat
    28501 acggcatcat gcggcatttc agttgcgtga agaagcgcac cacatcacag gactcatcat
    28561 cgtaggccca cggcacacga taagatttgc taccgtgtaa acggctatgg ctggagagca
    28621 aaccaaacgc gcaccagcgt ttgtaaacgt gcgccggagc ggtattttca aagccgccga
    28681 tatcgtggct ccagaagcca aaacctgaaa ggccaataga caaaccaccg cgcaggcttt
    28741 ccgccattga ttcgtagtta gcgtaacaat cgccacccca gtgtaccggg aatttctgcg
    28801 caccgacgga ggccgagcgg gcaaacaaga cagcttcttc ctcaccaacg gtgtccttga
    28861 gcacgttcca caccagttcg ttgtagatgt acgcataatg gttatgcatt ttctgcggat
    28921 cggaaccgtc aaaccactga acatcagttg ggatacgttc gccaaagtcg gtcttaaagc
    28981 aatcaacgcc catcgcgacc agacctttca gtttgtcggc gtaccatttg caggcatccg
    29041 gattggtaaa gtcataaatc gccagacctg gctgccattt atcccactgc catagcgaac
    29101 cgtccgggcg tttgagtaaa tagcctttct cttgtaactc tttaaagacg ggggattttt
    29161 gaccgatata ggggttaatc cagacgcaga ttttcagtcc tttcgctttc aggcggcgga
    29221 tcatcccttc cgggtcaggg aaagtcagcg ggtcccactc aaaatcgcac cactggaagg
    29281 ctttcatcca gaaacagtca aagtggaaaa catgcagcgg cagattgcgt tccgccatac
    29341 catcgataaa gctgtttacc gtcgcttcgt cgtagttggt ggtaaatgaa gtggttagcc
    29401 acaggccgaa ggaccacgcg ggcggcagcg ccggacgacc agtaaagcgg gtataacgat
    29461 caagtaccgc tttcggcgtc gggccgtcga taacaaagta ttcgagatat tcactctcaa
    29521 cgctgaactg cactttggag actttctccg atcccacttc aaaagagaca cactggggat
    29581 gattgaccag taccccataa ccacggttag tcatgtagaa cgggatattt ttatacgcct
    29641 gttcagtact tgtgccgccg tcccggttcc aggtctctac cgtctggcca ttgcgcacca
    29701 gggcagtaaa gcgctctccc agaccgtaaa ctgtttcgcc aacgccaaga tcaagccgct
    29761 caaacatata attgcgttga ttattcgtgt cctgcacgta gccattattt ttcacctgac
    29821 taccggtaat acgttcgccg ttgcgcagaa aatccagtga ccagaactca cctttgctga
    29881 cacgcgcgct taagttgcca cttttaaact cagcataacg ttctgtgttt tcgattgtga
    29941 ccttcacgtc ctgcaaaata ttgagcggat aatgaggacc gttattcagc gccccctgaa
    30001 aatgctcaat ccgcacaccg acaatacctt cctgtgggga gaaaaagcgc aacgtaaata
    30061 aaggcgtatc aagctgccag gtacgttcac gcacatcacg gggggcagca tagaccacca
    30121 tttcattatc ctgctgttca acctcgaaca cctgaagcgg gtgaatcaaa ttgaggccag
    30181 gttgaatcaa ccagtttcca tcgctaattt tcattgccgt tccttagttc tgcacttctt
    30241 gagaggtgaa ttgttgctgg caacggcgtt taccctgagc cagctgttcc ataacggttt
    30301 tcagattgtg cgtcgtgagt gagtagtagc gtttagcgat aatcgcgctc agcaaataac
    30361 agatcgccgg aacaatcgtg aatagcgcaa taatgatgct aatcgtggcg ctgttctgcg
    30421 ctttttctgc cgcatcatat ccgccataag ccagcatcca gccgataaga gcgccgccga
    30481 aggccaaccc cagtttgagc acaaacagcg tgccagcaaa actgatcccg gtcaggcgtt
    30541 taccattgca ccactcgccg tagtcgacgg tatcggacat cattacccac tggataggtg
    30601 tcaccagttg atgcaacaca ccaatcacga agatgaagac aaacatagtg atgctggcct
    30661 gcatgggaac aaagaacatc gcgaggctaa tcactgccag cagggcgttc gtccaccaga
    30721 agatagtgac tttacatttc cagtcggtca gaggttttgc cagtgcggaa ccaatcaggt
    30781 tacccacgca ataagtggtg agaaaagcga caaacacttc cggcgtgccc aaaatccatg
    30841 tgacgtaata catcatcgcc ccaccgcgta cgcacaccgc caggatattg aaaatggtta
    30901 gtaaaccgac aatccgccac tggtcgtttt gccagatatc acgtaaatct tcccgcatag
    30961 acgttgttgt aggtggtgct tcaacgcgtt ctttagtggt gaagaaacaa aatgccagca
    31021 tcatgaatgc caccacggaa aggaccgcga taccgccctg gaaaccgagt ggtttattat
    31081 caccgccaat taaattaacc agtggcatca tcagaacagt agaaagcatg cctcccgcgg
    31141 tcgccagcac aaaacgccag gattgcagcg agatacgctg agtcgggtca ttggtgatta
    31201 caccacccaa tgcgcagtaa gggatattga cgacggtata aagtaaggta agtagggtgt
    31261 aagtaattgc tgcatagatc attttgccgt tcatactgag atctggcgtg ctataggcca
    31321 gtacacagac gatcccgaat ggcagtgcgc caaacagtac ccacggacga aatttacccc
    31381 agcgagagcg cgttcgatcg gccaacaacc ccatgcaagg atcggaaatc gcatccagtg
    31441 cacgagcgac caaaaacatg gttccgacaa aaccggcagg aatgccaaaa atatcggtat
    31501 aaaagaacat catatataac attacgttat cgaaaataat gtggctggcg gcgtctccca
    31561 tgccataacc aattttctct ttaacggaca acacttcact cttcatctgc ttttccttga
    31621 tgctataggg gtgctgagac cgataacgca ttttgtaaac catccctgtg agagcgaata
    31681 ttccgatatc tggttattaa tttatgattc ttgttttatg tgatcgtggt agcgttaatt
    31741 tcgctcatat atcattgtaa aatataggtt ttatatgaac tataatgctt tcgtgataat
    31801 acgctgcgtg tattaggcgg aaaaaactga tctgggggat gtagaaactc aaggaagtag
    31861 ctataatgcg ccccgcctcc atgtagcaat cgaggcgcgg aagatcgtcg tctccggtga
    31921 ggcggctgga cttcaaatcc agttggggcc gccagcggtc ccgggcaggt tcgactcctg
    31981 tgatcttccg ccaaaatgcc tctcctgacg ttctccaacc ccttgtaata ctgtcaatcc
    32041 agatattttc tactgctcaa tattcaatcg gcttcaggaa tacctggtct aaggttttgt
    32101 gatggacgat gagcggctga agaatccgcc tgtcggttct tctgtcctcg aacgcatccg
    32161 cgatattcac gccagtatgc gccgtgttta tttgcaggtg atttgccccc ctgctgactc
    32221 tcagccaact gtatcgccat taaggtgaag atgttgtttt actcgcccca gaacaccctt
    32281 ttttatacga ctattctatt tctttaaccg ctggcgaaaa aaaactgact ataaacttc
//
LOCUS       DAZUDJ010000055        32185 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.055, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000055 DAZUDJ010000000
VERSION     DAZUDJ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32185
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.055"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(199..2832)
                     /gene="mngB"
                     /locus_tag="ACHY1N_003389"
     CDS             complement(199..2832)
                     /gene="mngB"
                     /locus_tag="ACHY1N_003389"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HFS4045633.1"
                     /translation="MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQD
                     NEYKYYVLDGQTAILEDYFAVKPENKDRVKKQVEAGKLIIGPWYTQTDTTIVSAESIV
                     RNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
                     TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLP
                     NGHDQMPLQQNIFEVMDKLREIYPQRKFVMSRFEEVFEKIEAQRESLATLKGEFIDGK
                     YMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILK
                     NHAHDSIGCCCSDKVHREIVARFELAEDMADNLLRFYMRKIADNMPQSDADKLVLFNL
                     MPWPREEVINTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPF
                     MEFDIQINQIVPSMGYRTLYIEANQPGNVIAAKSDAEGILENAFWQIALNEDGTLQLV
                     DKDSGVRYDRVLQIEESSDDGDEYDYSPAKEEWVMTSATAKPQCEITHEAWQSRAVIR
                     YDMAVPLNLLERSVRQSTGRVGVEMVVTLSHNSRRIDVDINLDNQADDHRLRVLIPTS
                     FNTDSVLADTQFGSLTRPVNDSAMNNWQQEGWKEAPVPVWNMLNYAALQEGRNGMAVF
                     SEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLFLRPGRPSGIKMPVPDSQLRGLLSC
                     RLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKLNKAGFNVPESYSLLKMPP
                     VGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQ
                     GSNLSGPFLPGQSRTFSYRLA"
     gene            complement(2850..4765)
                     /gene="mngA"
                     /locus_tag="ACHY1N_003390"
                     /pseudo
     CDS             complement(2850..4765)
                     /gene="mngA"
                     /locus_tag="ACHY1N_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393949.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
     gene            4934..5656
                     /gene="mngR"
                     /locus_tag="ACHY1N_003391"
     CDS             4934..5656
                     /gene="mngR"
                     /locus_tag="ACHY1N_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-D-glycerate transport/metabolism system
                     transcriptional repressor MngR"
                     /protein_id="HFS4045634.1"
                     /translation="MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRV
                     TVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIF
                     EVIPADDFLQQQLQITAQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENS
                     KYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEY
                     SRNAFNTDDYKFTLIAQRKSSR"
     gene            complement(5760..6629)
                     /gene="sucD"
                     /locus_tag="ACHY1N_003392"
     CDS             complement(5760..6629)
                     /gene="sucD"
                     /locus_tag="ACHY1N_003392"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HFS4045635.1"
                     /translation="MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKG
                     GTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEA
                     AAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKTVLK"
     gene            complement(6629..7795)
                     /gene="sucC"
                     /locus_tag="ACHY1N_003393"
     CDS             complement(6629..7795)
                     /gene="sucC"
                     /locus_tag="ACHY1N_003393"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HFS4045636.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIG
                     AVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK"
     gene            complement(7889..9106)
                     /gene="odhB"
                     /locus_tag="ACHY1N_003394"
     CDS             complement(7889..9106)
                     /gene="odhB"
                     /locus_tag="ACHY1N_003394"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA];
                     GO_function: GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HFS4045637.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEDEGTTVTSRQIIGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAP
                     AAADPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRK
                     QYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTP
                     RGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMS
                     TPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIK
                     ELLEDPTRLLLDV"
     gene            complement(9121..11922)
                     /gene="sucA"
                     /locus_tag="ACHY1N_003395"
     CDS             complement(9121..11922)
                     /gene="sucA"
                     /locus_tag="ACHY1N_003395"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA];
                     GO_function: GO:0004591 - oxoglutarate dehydrogenase
                     (succinyl-transferring) activity [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HFS4045638.1"
                     /translation="MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRST
                     FQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNL
                     YRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPE
                     AVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT
                     FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAM
                     QEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVE"
     gene            complement(12123..12839)
                     /gene="sdhB"
                     /locus_tag="ACHY1N_003396"
     CDS             complement(12123..12839)
                     /gene="sdhB"
                     /locus_tag="ACHY1N_003396"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit
                     SdhB"
                     /protein_id="HFS4045639.1"
                     /translation="MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRNA"
     gene            complement(12855..14621)
                     /gene="sdhA"
                     /locus_tag="ACHY1N_003397"
     CDS             complement(12855..14621)
                     /gene="sdhA"
                     /locus_tag="ACHY1N_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HFS4045640.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            complement(14621..14968)
                     /gene="sdhD"
                     /locus_tag="ACHY1N_003398"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             complement(14621..14968)
                     /gene="sdhD"
                     /locus_tag="ACHY1N_003398"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HFS4045641.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     YEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            complement(14962..15366)
                     /gene="sdhC"
                     /locus_tag="ACHY1N_003399"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             complement(14962..15366)
                     /gene="sdhC"
                     /locus_tag="ACHY1N_003399"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0045273 - respiratory chain complex II
                     (succinate dehydrogenase) [Evidence IEA];
                     GO_function: GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HFS4045642.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFI
                     AVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFG
                     YLEETFEAGKRSAKISFVITVVLSLLAGVLVW"
     gene            15747..15854
                     /locus_tag="ACHY1N_003400"
     CDS             15747..15854
                     /locus_tag="ACHY1N_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045643.1"
                     /translation="MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV"
     gene            16060..17343
                     /gene="gltA"
                     /locus_tag="ACHY1N_003401"
     CDS             16060..17343
                     /gene="gltA"
                     /locus_tag="ACHY1N_003401"
                     /EC_number="2.3.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004108 - citrate (Si)-synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HFS4045644.1"
                     /translation="MADTKAKLTLNGDTTVELDVLKGTLGQDVIDIRTLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYD
                     EFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWSEMHSDGMKIARPRQLYTGYEKRDFKSDIKR"
     gene            17734..18300
                     /locus_tag="ACHY1N_003402"
     CDS             17734..18300
                     /locus_tag="ACHY1N_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4045645.1"
                     /translation="MFKGQKTLAALAVSLLFTAPVYAADEGSGEIHFKGEVIEAPCEI
                     HQDDIDKEVELGQVTTSHINQSHHSDAVAVDLRLVNCDLENSSNGSGGKISKVAVTFD
                     SSAKTTGADPILNNTSTGEATGVGVRLMNKDQSNIVLGTATPDIDLAPTSSEQTLNFF
                     AWMEQIDQATPVTPGAVTANATYVLDYK"
     gene            18351..20810
                     /gene="ybgQ"
                     /locus_tag="ACHY1N_003403"
                     /pseudo
     CDS             18351..20810
                     /gene="ybgQ"
                     /locus_tag="ACHY1N_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706516.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0015473 - fimbrial usher porin activity
                     [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
     gene            20825..21556
                     /gene="ybgP"
                     /locus_tag="ACHY1N_003404"
     CDS             20825..21556
                     /gene="ybgP"
                     /locus_tag="ACHY1N_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706517.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0061077 - chaperone-mediated protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HFS4045646.1"
                     /translation="MTFMKGLPLLLLVASLCSHAALQPDRTRIVFNANDKATSLRVDN
                     RSDKLPYLAYSWLENEKGEKSDDLLVALPPIQRLEPKATTQVRIVKQASTTKLPGDRE
                     TLFFYNMREIPPAPEKNSDHAVLQVAIQSRIKVFWRPAALRKKAGEKVELQLQVSQQG
                     NQLTLKNPTAYYLTIAYLGRNEKGVLPGFKTVMVAPFSTVNTNTGNYSGSQFYLGYMD
                     DYGALRMTTLNCSGQCHLQAVEAKK"
     gene            21553..22614
                     /gene="ybgO"
                     /locus_tag="ACHY1N_003405"
     CDS             21553..22614
                     /gene="ybgO"
                     /locus_tag="ACHY1N_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415244.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4045647.1"
                     /translation="MSAGKGVLLVICLLFLPLKSALALNCYFGSSGGSVEKSEAIQPF
                     AVPGNAKLGDKIWESDDIKIPVYCDNNTNGNFESEHVYAWVNPYPGVQDRYYQLGVTY
                     NGVDYDANQGKSRIDTNQCIDSKNIDIYTPEQIIAMGWQNKICSGDPANIHMSRTFLA
                     RMRLYVKIREMPPHDYQSTLSDYIVVQFDGAGSVNEDPTAQNLKYHITGLENIRVLDC
                     SVNFSISPETQVIDFGKFNLLDIRRHTMSKTFSIKTTKSQNDQCTDGFKVSSSFYTEE
                     TLVEEDKALLIGNGLKLRLLDENASPYTFNKYAEYADFTSDMLVYEKTYTAELSSIAG
                     TPIEAGPFDTVVLFKINYN"
     gene            22766..23812
                     /gene="abrB"
                     /locus_tag="ACHY1N_003406"
     CDS             22766..23812
                     /gene="abrB"
                     /locus_tag="ACHY1N_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415243.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFS4045648.1"
                     /translation="MPVLQWGMLCVLSLLLSIGFLAVHLPAALLLGPMIAGIIFSMRG
                     ITLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAANWPIVLAILLVTLLSSAIVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRM
                     MLGDNAEAVNQQIVWFPPVSINLLLTILLAVVAGTAGCMLRLPSGTMLIPMLAGAVLQ
                     SGQLITIELPEWLLAMAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGM
                     AWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIMAMQTLRLFSILLTGPA
                     IARFISTYAPKRSA"
     gene            complement(23809..24600)
                     /gene="nei"
                     /locus_tag="ACHY1N_003407"
     CDS             complement(23809..24600)
                     /gene="nei"
                     /locus_tag="ACHY1N_003407"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000703 - oxidized pyrimidine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HFS4045649.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKTYQSQLIGQH
                     VTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTIL
                     LYSASDIEMLRPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLD
                     QAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLEIPRFSYATRGQVDE
                     NKHHGALFRFKVFHRDGELCERCGGIIEKTTLSSRPFYWCPGCQH"
     gene            complement(24636..25370)
                     /gene="pxpA"
                     /locus_tag="ACHY1N_003408"
     CDS             complement(24636..25370)
                     /gene="pxpA"
                     /locus_tag="ACHY1N_003408"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HFS4045650.1"
                     /translation="MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQIMQACV
                     REAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRH
                     VKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGKQYGLTTREEVF
                     ADRGYQADGSLVPRSQRGALIENEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLH
                     GDGEHALAFARRLRSTFAEKEIVVAA"
     gene            complement(25360..26292)
                     /gene="pxpC"
                     /locus_tag="ACHY1N_003409"
     CDS             complement(25360..26292)
                     /gene="pxpC"
                     /locus_tag="ACHY1N_003409"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpC"
                     /protein_id="HFS4045651.1"
                     /translation="MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLV
                     GNDANAPALEITLGQLTVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMKAGQRLTL
                     KRPQHGMRSYLAVAGGIDVPPVMGSCSTDLKVGIGGLEGRLLKDGDRLPIGKSKRDFM
                     EAQGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSSQSNRMGYRLQGQILKR
                     ITDRELLSHGLLPGVVQVPHNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQ
                     PIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN"
     gene            complement(26286..26942)
                     /gene="pxpB"
                     /locus_tag="ACHY1N_003410"
     CDS             complement(26286..26942)
                     /gene="pxpB"
                     /locus_tag="ACHY1N_003410"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HFS4045652.1"
                     /translation="MQRARCYLIGETAVVLELEPPVTLASQKRIWRLAQRLVDMPNVV
                     EAIPGMNNITVILRNPESLALDAIERLQRWWEESEALEPESRFIEIPVVYGGAGGPDL
                     AVVAAHCGLSEKQVVELHSSVEYVVWFLGFQPGFPYLGSLPEQLHTPRRAEPRLLVPA
                     GSVGIGGPQTGVYPLATPGGWQLIGHTSLSLFDPARDEPILLRPGDSVRFVPQKEGVC
                     "
     gene            complement(26965..27708)
                     /gene="ybgI"
                     /locus_tag="ACHY1N_003411"
     CDS             complement(26965..27708)
                     /gene="ybgI"
                     /locus_tag="ACHY1N_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HFS4045653.1"
                     /translation="MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTA
                     SQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDT
                     GPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTDLDVTFIDIPNPA"
     gene            27979..29460
                     /gene="dtpD"
                     /locus_tag="ACHY1N_003412"
     CDS             27979..29460
                     /gene="dtpD"
                     /locus_tag="ACHY1N_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HFS4045654.1"
                     /translation="MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYND
                     THAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSF
                     LYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGY
                     AQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLV
                     LLVATPALITVLFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFF
                     SMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKE
                     SVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSSMYGHSSLPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINY
                     SINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES"
     gene            complement(29502..30920)
                     /gene="phrB"
                     /locus_tag="ACHY1N_003413"
     CDS             complement(29502..30920)
                     /gene="phrB"
                     /locus_tag="ACHY1N_003413"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HFS4045655.1"
                     /translation="MITHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWAT
                     HNMSPRQAELINAQLNGLQIALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFY
                     NYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLK
                     RLREGMPECVAAPKVRSSGSIEPAPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQN
                     GAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLSEL
                     IWREFYRHLMTYYPSLCKHCPFIAWTDRVQWQSNPAHLQAWQKGKTGYPIVDAAMRQL
                     NSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTD
                     AAPYFRIFNPITQGEKFDREGEFIRRWLPELRDVPGKAVHEPWKWAQKAGVMLDYPQP
                     IVDHKEARLRTLAAYEEARKGA"
     gene            complement(30917..31426)
                     /gene="ybgA"
                     /locus_tag="ACHY1N_003414"
     CDS             complement(30917..31426)
                     /gene="ybgA"
                     /locus_tag="ACHY1N_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HFS4045656.1"
                     /translation="MNQQRFDDSTLIRIFALHELHRLKEHGLTRGALLDYHSRYKLVF
                     LAHSQPEYRKLGPFVADIHQWQNLDDFYNQYYQRVIVLLSHPANPRDHTNVLMHVQGY
                     FRPHIDSTERQQLAALIDSYRRGEQPLLAPLMRIKHYMALYPDAWLSGQRYFELWPRV
                     INLRHSGVL"
     gene            complement(31577..32185)
                     /locus_tag="ACHY1N_003415"
                     /pseudo
     CDS             complement(31577..32185)
                     /locus_tag="ACHY1N_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT         7750 a         8653 c         7858 g         7924 t
ORIGIN      
        1 tatacgtggc ttgagagtga agataaacgc aaaattacct gatgcgctac gcttgccagt
       61 gtctacatca tctctgcaat atattgaatt tgcctgcttt tgtagaccga ataaagcgtt
      121 catgccgtat ccggcatgaa caaagcgccc tttgtcaaca atctggccgc gcatatgtgg
      181 cttcggtttg attgctattc aggcaagccg gtaactgaac gtccgtgact ggccgggtaa
      241 aaaaggcccc gatagatttg aaccttgatt ttcctcggtg gtaatgtgtt catccatcat
      301 cgtttctgag caagaaatca cctcgcgact gaaagcaaca gtcgcatcac aggttgctga
      361 ttcagccgga ttaaacagcc gtaaaatcac ttcttgtcgg tcttcagctt tcttaagtgc
      421 gcttatcagg catcccactg ggggcatttt caacaaacta taactttccg gcacgttgaa
      481 tccggctttg ttgagcttca tcgcatccca tgggattttg ttgtaacact gtactggagt
      541 cagccatgct cgcgcctgct gagctacacc agcggcggtt ggcgtaccgg tataactcaa
      601 taaacttagg cgacaagaaa gcagaccacg tagttgtgag tccgggactg gcattttaat
      661 tcccgaaggc cgcccaggcc ttaaaaacag atcttctttg cccagtaagc ccacgccacg
      721 cagcaacgta atggcaaagg ttttcttctc ttcaccgatg acttcaaatt cacgtagccc
      781 ttcgctaaag acagccatgc cgttacgccc ttcctgtaag gctgcatagt tgagcatatt
      841 ccataccgga accggcgctt ctttccagcc ttcttgctgc cagttgttca ttgcactgtc
      901 gttcacgggg cgcgttagcg aaccaaactg ggtatctgcc agaacactat cggtgttaaa
      961 agatgtaggg atcaggacgc gaaggcgatg atcgtcagcc tggttatcaa ggttgatatc
     1021 cacatcaata cgtctgctgt tatgactcag agtgacaacc atctccaccc ctactctgcc
     1081 cgtggattgc cggacgcttc gttccaacaa attgagcggc accgccatgt catagcggat
     1141 aacagccctg ctctgccagg cctcatgagt aatctcgcat tgcggtttcg ctgttgcaga
     1201 agtcattacc cactcttctt ttgcgggtga atagtcatat tcatcaccat catcagagct
     1261 ttcttcaatt tgcaacaccc ggtcatagcg cacaccgcta tctttatcta ccagttgtag
     1321 cgttccatcc tcattgagcg caatttgcca gaaagcattt tccagtatcc cttcagcgtc
     1381 actttttgct gcaatcacgt tgccaggctg attcgcttcg atataaagcg tgcgatagcc
     1441 catagaaggg acaatctggt tgatctgtat atcaaactcc ataaagggat cgtaattacc
     1501 gtaatgaact atttgccgat cgattaggcc tggatcgatc tcacgggcat ggcgaataaa
     1561 atacggtaca ggctgaccgc gatcgtctcg tagattaaac tggctggcgc gcaggcgcac
     1621 agtggtgtta ataacttctt cccgcggcca gggcatcagg ttaaacagca cgagtttgtc
     1681 ggcatcactc tgtggcatgt tatcggcaat tttgcgcatg tagaaacgca gcagattatc
     1741 cgccatgtct tcagccagtt cgaagcgggc gacaatttcg cgatgaactt tgtcactgca
     1801 acaacaaccg atactgtcgt gggcatgatt ttttaagatc tctttccaca ttttctccag
     1861 caagccgtgg tggtattcaa aacccaacgt ccaggccagc gttgccagtg gttccagcag
     1921 attaacaatc ttattttcaa tacgtgcgtg ggcaattttg atatccatgc gcgtggaacc
     1981 gatggtgcga tgtacgcgca tatatttgcc atcgataaat tcacctttca gggtggccag
     2041 actttcacgc tgcgcttcga tcttctcaaa tacctcttca aagcggctca tcacaaactt
     2101 acgttgaggg tagatctcac gtagcttatc catcacttcg aagatatttt gctgcaatgg
     2161 catctggtca tgcccattcg gcagcaaaat ctctttggtt acagacgctt tttccagcac
     2221 gtcaaaataa ctgtcgaggc gtttacgtaa tccgttttcg tcggcaggta agtacttacc
     2281 gatggcgtag cccagcggca gcacctgcgc cgtcacttcg ctaccgtcac tgctttgcca
     2341 caaaaactcg gttttatcag taccgtggcg ctccgaacat ccgcgccaga acatggtgcg
     2401 ggtaatgcca aatccattgt agatatgcgg cagttgcccg gacatgccaa aggaatctgg
     2461 taaataacct attttcatcg gctcgccaaa cgcgaggcag tcacgcattc cgtacatcag
     2521 attacggacg atggattccg cagaaacaat cgtggtatcg gtctgggtat accaggggcc
     2581 gataatcaac ttgccggctt ctacctgttt cttcacgcgg tctttgtttt ccggtttcac
     2641 cgcgaaataa tcttcgagga tcgccgtttg cccgtcgagt acgtaatatt tgtattcgtt
     2701 gtcctgttcc agtcggcaca ggatctcttc catattattg accagcagaa tgcgtgactc
     2761 ttcggtggtg aaataccact cccgatccca atgcatatgc ggggtgatgt gaacgcgaga
     2821 taccgctttc atcgtcgttt cctttttgtt tatggcatta cgccatcagt cagatagttg
     2881 ccatgcttaa ccgcgtgacg ccgccagatc aggagaattg cagtcgagat tgcagccccc
     2941 accaatgccg caccaaacca gccaattgcc gccataacac cgcccgcgcc attatcatga
     3001 agtaaaaaga gcgagaaaat gccggcaccg ggtgtcgaaa ggccgatatt catcgcaccg
     3061 acaatagcgc ccgttaccat agagcccagc acaaacgaac caataacccg cagcggatct
     3121 tcaatcgcca tcgggatcgc cccttcggta atacctgcca gccctaacag ccaggtggat
     3181 ttcccggtct caatttcaaa ctctttaaac aggcgcggtg cgagcatcgt ggaagcggtt
     3241 acggtaaatg ccgaaaccat tttgacggag gcgaaaatgg catacgggcc gtaaacgccg
     3301 ttcgccattg cgcccaggca gaatgcataa gcggctttgt tcactggccc tccaaggtca
     3361 aaggaacaca taaaaccgag aatggcaccc agcaacagcg cgttacttcc tgacagaccg
     3421 ttcagccagg cggtaagcga gttattgatc caggcgacag gttctcccac cacaaacagc
     3481 atcagactgc ccgctcccaa cgtaccgagc accgggtaga gataaaaagt caggaatcca
     3541 ttgaatttac tgctaagacg caagtgattt ttcacccagc gcatcaagta accggctatc
     3601 aatccgccaa cgaccgcgcc gagaaacccg gagccgatca tgttggcggc aagtccagcc
     3661 gcaaagcctg gcgctaacgc cggtttatct gccagagaat aggcggtata ggccgcgagc
     3721 accggtacca tcaaaattcc gagcagcccg ccgcccagct tgcggtacat ccacagccag
     3781 gagttttctt cattaaacag atcttgtagc ccgaagattt gcgacagtaa taccgcgacc
     3841 gccagcaccg tgccccccgc gacaatcaac ggtacggcaa aagagattcc gctcaacagt
     3901 gcctgtttca gctccgtttt gacacttttc accggttgcg tatcttgctg tacggtacgc
     3961 gtctcatcgc tacgcttgag ggtaagcgct tgttggatca acgcttctgc atggcgaatc
     4021 ggctcggcaa caggcactga aagcgcggga tgccattaaa acgctcactc tccttgatgg
     4081 cgacttcagc cgcaaaaata caggcggttg cactattgag ttgatccgcc gttaaacgcc
     4141 cttcaatgcc gttagcgcct tgtttttcaa cgtaaacatt tacgccgagt ttgcgtccgg
     4201 ctttttccag atattccgca gccatatagg tgtgagcaat acccgccgga caggccgtta
     4261 cgcagacgat agttggcgcg ttggaaaaag aggcagaagg ttgcgtgcct cccttgtcat
     4321 ccagcgccga gagcaactca tcaggcgtcg tcgccgactg tatacgcgcc cgaatctcat
     4381 catccgccag gcgcgtggtc agcgctgtca gcagttgcat atgcgtagta cccgcttcat
     4441 tggggggaat cgccagcagc accactaaat caaccgcttc cgggccatca acgccttccc
     4501 actgaagcgg ctcgctgagt gtggcgaccg caaacgccgc ttcttttacc gcagcagttt
     4561 tgccatgcgg cacagccaac ccttcaccta aggcggtcgg gccaaggctt tcacggcgat
     4621 acacttcttc cagaaattgc tcagtactgg aaattttccc cagagcagca agacgttgag
     4681 tcaacgcgtg gatggcctct tcacggctgg taaagcgcgc attcagacac aacgcatcgc
     4741 ggtgggtcag agtcgtcaga ttcatcatga tcctcacttg atcgttttta tagtcgcgcc
     4801 agtgtgcccg ataaaacaat accattatgt gatcaatttc acttgattga aattatttgt
     4861 attgtatttg tattatttac aggatgaatt tatcgggcat aatggctaaa ttcgtattaa
     4921 tgagatacta aaaatgggac acaagccctt ataccggcag attgccgatc gcattcgtga
     4981 acaaattgcg cgtggcgagc ttaaacctgg cgatgcgtta cctaccgaat cggcattaca
     5041 aacagagttt ggcgtcagcc gggttacggt gcgtcaggct ttgcgccagt tagtcgagca
     5101 acagatcctc gaaagcattc agggcagcgg gacttacgtc aaagaagagc gggtcaatta
     5161 cgatattttt cagttaacca gttttgatga aaaactgtcg gaccgtcacg tcgatacaca
     5221 cagtgaagtc ctgatatttg aagtgattcc ggctgacgat tttcttcagc aacagctaca
     5281 aatcaccgcg caggatcgtg tgtggcatgt gaagcgcgtg cgctatcgca agcaaaagcc
     5341 aatggcgctg gaagaaacct ggatgccgct tgcgttgttc ccggatctca cctggcaggt
     5401 catggaaaat tcaaaatatc actttattga agaagtgaag aaaatggtta tcgatcgtag
     5461 cgaacaggaa atcattcctc tgatgccaac cgaagagatg agccgtctgc ttaatatcag
     5521 ccagacaaag ccgattcttg aaaaagtatc gcgtggatat ttagttgatg gtcgggtgtt
     5581 tgaatatagc cgcaacgctt ttaataccga tgactataaa tttaccctga tagcgcaacg
     5641 aaaatcatcg cgataagcac aaaaaaggcc atcatacgat ggccaaccat gtcgaaaccg
     5701 acagcccttc gccattcctg tagagggaag cggcgagggc tatttcttat tacagatatt
     5761 tatttcagaa cagttttcag tgcttcaccg atatccgcca ggctgcgaac ggttttcacg
     5821 cctgcggctt ccagagcagc gaatttctca tccgcagtcc ctttcccacc ggcaatgatg
     5881 gcgcccgcgt ggcccatacg tttgcctttc ggcgcagtca caccagcgat gtaacccaca
     5941 actggcttgg taacatgctc tttgatgtac gctgccgctt cttcttcagc gctaccgccg
     6001 atctcaccga tcattacgat cgcttcggtc tgcggatctt tttcgaacat ttcgagaatg
     6061 tcgataaagt tagagccagg gatcgggtca ccgccgatac caacacaggt cgactgaccg
     6121 aaaccgtaat ccgtggtctg tttaaccgct tcataggtca gtgtaccgga acgggaaacg
     6181 atacccactt tacccggttt gtgaatgtga cccggctgga taccgatttt gcattcaccc
     6241 ggagtgataa cgcccgggca gttcgggccg atcatacgaa cgccggcttc gtccagtttc
     6301 actttcacag tcagcatatc cagcgtcggg atgccttcag tgatggtgat aatcagtttg
     6361 atgcctgcat caatagcttc cagaatggag tctttgcaga acggtgctgg tacgtagata
     6421 acagaagcgg tagcgccagt agcagcaaca gcttcacgca cggtgttgaa caccggcagg
     6481 ccgaggtggg tagtaccgcc tttacctggg gttacgccgc caaccatttt agtgccgtat
     6541 gcaatggcct gttctgagtg gaaagtcccc tggctaccag taaagccctg gcagataacc
     6601 ttggtgtttt tatcaattaa aatggacatt atttcccctc cactgcggca acaacctgct
     6661 gagctgcatc cgtcagacct tttgctgcaa taatattcag gccgctgtca gccagtttct
     6721 tcgcgccgag ttcggcgttg ttaccttcca gacgtaccac gaccggtacg ttaacaccca
     6781 cttctgctac cgcgccgatg ataccgtcag cgatcaggtc gcaacgaacg ataccgccga
     6841 agatgttaac cagaacggct ttcactttgt cgtcagagag gatgattttg aacgcttcgg
     6901 ttacacgttc tttggttgcg ccgccgccaa cgtcaaggaa gttagccggt tcgccgccgt
     6961 gcagtttaac gatgtccatc gtacccatcg ccagacctgc gccgttaacc atacaaccga
     7021 tgttaccgtc cagcgcaacg tagttcagtt cccactgtgc agcctgtgct tcacgcggat
     7081 cttcctgcga ctggtcacgc atttcgcgca gatcaggctg gcggaacagt gcgttgccgt
     7141 cagcgcccag tttgccgtcg aggcaaatca gatcgccctg tttggtgatg accagcgggt
     7201 tgatttcgat caacgccagg tcgcgctcca ggaaaatggt cgccaggccc atgaagattt
     7261 tggtgaactg ctgaaccagt ttaccttcca gacccagttt gaacgccagc tcgcgtccct
     7321 gatacggcat cgggcctgtc agcggatcaa gcgcaacttt atggatcagg tgcggagttt
     7381 cttccgccac tttttcgatt tccacgccgc cttcggtgga ggccataaag accacgcgac
     7441 gggaactacg gtctacaacg gcaccgagat acagctcttt agcgatatcg gtcgctgctt
     7501 caaccagaat ctggttaacc ggttggccat tggcatctgt ttgatacgtt accagacgct
     7561 tgccgagcca gttttctgca aaagcacgga tgtcttcttt gctgtttaca actttcacac
     7621 cgcccgcttt accgcggcca ccagcgtgaa cctgacattt cactacccac gggccggcac
     7681 cgatttttga agcggcttct tctgcttcgc gcggagtagt acaggcataa cccaccggtg
     7741 ctggtaagcc atagcgggca aaaagttgtt ttgcctgata ttcatgtaag ttcatgtgtt
     7801 ctgtccatcc ttcagtaatc gttatctttt aaaccgtaga ccgacaccct atccacgtcg
     7861 gtctacagtg caggtgaagc ttaaactact acacgtccag cagcagacgc gtcggatctt
     7921 ccagcaactc tttgatcgtt accaggaagc ccacggattc gcgaccatcg atcagacggt
     7981 gatcgtagga cagcgccagg tacatcatcg gcaggatctc aacctgacca ttcaccgcca
     8041 tcggacgatc tttgatagcg tgcataccca gaattgcgct ctgcggcggg ttgatgatcg
     8101 gcgtagacat cagggaaccg aacacaccac cgttggtgat ggtgaagtta ccaccggtca
     8161 gatcttcaac ggtcagcttg ccgtcacggc ctttgactgc cagctctttg attttcttct
     8221 cgatgtctgc catgccgagg gtatcgacat cacgcagtac cggtgtcacc aggccgcgcg
     8281 gcgtagaaac cgccatgctg acgtcgaaat agttgtggta aaccacgtca tcgccgtcga
     8341 tagacgcgtt cacttccggg taacgtttca gggcttcaac caccgctttc acgtagaagg
     8401 acataaagcc cagacggatg ccgtggcgtt tttcaaacgc ttcaccgtac tgcttacgca
     8461 gatccataat cggcttcatg ttgacttcgt tgaacgtggt cagcatggcg gtggagtttt
     8521 tcgcttccag cagacgctct gccacacgct tacgcaggcg agtcatcggg acacgttttt
     8581 cactacgtgc agccagagcc ggttgcgccg ccggatcagc cgctgccgga gcagactctt
     8641 tcgccggggc tttcgccaga tgtttttcca catcttcacg agtcagacga ccacccacac
     8701 cggtgccttt aatggcgctg gcgtcgagat tgtgttcagc cagcaggcga cggatcgccg
     8761 ggcttaacgc atcgttgttt tgctcttcca gagacgcctg ctggcgttgc gccggagtgg
     8821 acgctttctc ttcagatttg gcgctggttt ctttaccggc gctgttgcct tcacgcaggc
     8881 gaccaatgat ctgacgagac gttaccgttg taccttcatc ttccagaacc gcatccagaa
     8941 tgccgtctgc tgatgccggt acttccagta ccactttgtc agtttcgatt tctaccagca
     9001 cttcatcacg tacgactgcg tcgccgggtt ttttatgcca ggttgcgacg gtggcatcgg
     9061 ctacggattc aggcaggtca gggaccagaa tatctacgct actcattgtg tatcctttat
     9121 ttattcgacg ttcagcgcgt cattaaccag atcttgttgc tgtttctggt gaacggacat
     9181 ataccctacc gccggagagg cggaggccgg gcggcctgca taacgcagag aagccccaaa
     9241 cggaatcact tcacggaaat gatgctggct gcagtaccat gcgccctggt tgagcggctc
     9301 ttcctggcac cagacaaaat ccttgacgtg agcaaactgc tgcaacactt cctgcatcgc
     9361 tttatgcggg aacgggtaga gttgctcgat acgcacaatg gcgacatcgt gttgattgtt
     9421 cttacgacgc tgttccagca ggtcgtaata aaccttacca gaacacatta ctacgcgctt
     9481 cacgcccttc ggatcaagct cgtcgatttc accgatggct ggcaggaagg tgccgttcgc
     9541 cagttcttcg aggctggaaa ccgccagcgg atgacgcagc agggatttcg gcgacatcac
     9601 gaccagcgga cgacgcatcc cgcgcagcgc ctgacgacgc agcatgtggt aaacctgtgc
     9661 cggggtagac ggtacgcaaa cctgcatgtt ttgctcagca caaagttgca gataacgttc
     9721 cagacgcgcg gaggagtgct ccggcccctg cccttcgtaa ccgtgcggca gcaacatcac
     9781 cagaccacac atccggcccc atttctgctc gccagaggag atgaactggt cgataaccac
     9841 ctgcgcaccg ttggcgaagt caccgaactg cgcttcccag atggtcaggg tgcgtggttc
     9901 tgcggtggca taaccgtatt caaacgccag cactgcttct tcagacagta cggagtccca
     9961 aacacggaac gcgccctggc cgttatggat gtgttgcagc ggcgtgtaag tggaaccgtt
    10021 agactggttg tggatcaccg cgtggcggtg gaagaaggta ccgcgaccgg agtcttcacc
    10081 cgacaggcga accggaatgc cttcgtcaac cagcgtggcg taagcgaggt tttccgcgcc
    10141 gccccagtcg aacagtttct caccggcagc catcgcctgg cgatcgccat aaatcttggc
    10201 aacgcgagac tgcatttcaa ccgcttccgg caccgtgctg atgcgtttag ccagttcctg
    10261 caggcgcttc atctcaactt tgttcgggta ctcttcgtcc cattcgtggt tgaggtacgg
    10321 cgaccaggtg aaagagtgca tgttcatcgg acgccactct gctaccacgc aatcgccagc
    10381 atccagcgca tcgcggtaca ggttaaccat ctcggtggca tcttccagcg tcgccacttt
    10441 ttcctgctcc agcttgtcag cgtagatttt gcgcggtgtc ggatgttttt tgattttctg
    10501 atacatcagc ggctgggttg cgctcggctc gtcggcttcg ttgtggccgt gacggcggta
    10561 gcataccagg tcgatgaaga catcacgttt aaaggtgtta cggaaatcga gcgccagacg
    10621 ggtcacaaag gcaacggctt ccggatcgtc cgcgttaacg tggaaaatcg gtgcctgaac
    10681 catcttgccg atatcagtac agtacggcgt agaacgggca tccagcggat tagaggtggt
    10741 gaaaccaacc tggttgttga taacgatacg taccgtaccg ccaacttcat aaccacgcgc
    10801 tttcgacatg ttcagggttt cctgaaccac gccctgtccg gtcactgcgg cgtcaccgtg
    10861 gatggtaatt ggcagcactt tgttgctgct cggctcatca agtctgtcca gacgggcacg
    10921 aacagagccg ataacgaccg ggcttacaat ctcaaggtga gacgggttaa acgccagcgc
    10981 caggtgcacc aggccgccat cggtctggaa gtcagacgag aagcccatgt ggtatttcac
    11041 gtcacccgtg ccgaggtgtt ctttatgttt accggcaaac tcgtcgaaca agtcttgcgg
    11101 ttttttaccc agcacgttca ccaacacgtt cagacgacca cggtgcgcca tcccgagaac
    11161 cacttcccgg gtgccgctgt tgccagcgtg gcggatcatc tctttaagca tcgggattaa
    11221 cgcgtcaccg ccttccagcg agaagcgttt tgcgccaggg aattttgcgc cgaggtaacg
    11281 ttcaaggcct tcagcggcgg tcagttcgct taagaagcgt tttttctctt cgctattgaa
    11341 agtcgcgcga ccagactcga tacgctgttg gatccagcgt ttttcttcgg tgctggtaat
    11401 gtgcatatac tcggcaccaa tcgggccgca gtaggtttgc ttgagggctt ccagcagctc
    11461 gccgagtttc atggtttctt tgccgctggc aaatgaaccg acgttgaagg tctcctggaa
    11521 gtctgcttcg gtcagatcgt ggaaagacgg atccagatcg gccactttat cttgctgcca
    11581 cagtcccagc ggatcgagat tcgcatgctg gtgaccacgg aagcggtatg cgttaatgag
    11641 ctgcaggact ttaacctgct ttacattggt gtcagggtcg gagatcgttg aagagtaacg
    11701 tgaagcgtct ttcgccaggc ggcggaaata ttcacgcgtt tgagagtgga attgatccgg
    11761 tttgactccc gtaccaggta actgctggaa cgtcgaacgc cagttagcgt caaccgagtc
    11821 aggatcggtt aagaagtctt catagagctg ttctatccag ctctggtttg cgccagagag
    11881 gtaagaagag tccaaccagg ctttcaaagc gctgttctgc atcgtgatcc cttaagcatc
    11941 ttttttatgc ttacttcgcc gtggatacta ccacgcacag ttatgtgcgt gccggggttc
    12001 acttgcgagc tcttgtctac gtagtggctc gcgaaggaac ctttaaaaac tgtcttagtg
    12061 tcaggggcag tttttaaaga tttcctgaat agccggggga tttccccggc atcaacattt
    12121 aattacgcat tacgttgcaa caacatcgac ttgatatggc cgatggcgcg cgtcgggttc
    12181 agccccttcg gacatacact gacgcagttc atgatgctgt gacagcggaa tacactgaat
    12241 gcatcgctca aaccgtcgag gcggctgtca gtctcggtat cacggctatc gatcaggaaa
    12301 cgatatgccg ctaacaagcc tgccgggccg ataaacttat cgggattcca ccagaaagac
    12361 ggacaagagg ttgaacaaca tgcgcagaga atacattcat acagcccgtc gagtttttcg
    12421 cgctgctctg gcatctgtaa atgctcgcga gctggcggat tttgtccatt attcaacagg
    12481 taaggcttaa ttttctcata ttgcgcatag aattgtccca tgtctaccac caaatcgcgg
    12541 atcaccggta aacctggcag cgggcgaatc acaatcttct tgcccggctg gttgagtgcc
    12601 gaaatcgggg taatacaggc cagaccattc ttgccgttca tgttcagacc gtcggaaccg
    12661 cacacacctt cacggcagga gcggcggaac gacaggctgg gatctttctc tttcagctgg
    12721 ataagcgcat ccagcaacat catgtcgcga ccttcttccg cttccagggt gtaatcctgc
    12781 atacgcggag catcatcaac atccgggtta tagcgataaa ttgaaaactc gagtctcatt
    12841 ttcctgtctc cgcattagta agtacgaatc ttcggcggga atgccgggcg cagtttcggt
    12901 tccatgttga cgcttcggcg cgtcatggat tccgactctg gcagatacag ggagtggcac
    12961 agccagtttt catcatcacg atccgggaag tcgaagcggc tatgcgcgcc acggctttcg
    13021 gtacggaagt tggcagaaac agccgttgca tacgccgttt ccatcaggtt atccagttcc
    13081 aggcactcaa cgcgctgggt gttgaactcg ctggaagtgt catccagacg ggcatttttc
    13141 agacgctcgc ggataacttt caactgctca agccctttcg ccatcgcatc accttcacgg
    13201 aagaccgaga agttatgctg catacattct tgcagcgctt tacgaatcgc caccggatct
    13261 tcaccgttac gattattgtt ccagcggttc agacgatcca gagatgcttc aacatcagac
    13321 tcgctggcat cgcgcaatgc gccctgctcg gcgatagact cttgcagatg cagacccgct
    13381 gcgcgaccaa agaccaccag gtccagcagc gagttgccgc ccagacggtt agcgccgtgt
    13441 accgatacac aagcgatttc accaacggca aacagccccg gaacaaccac atcttcgcct
    13501 ttctcgttca ccgtcagcgc ctgaccggtc actttggtcg gaataccacc catcatgtag
    13561 tgacaggttg ggataaccgg aatcggctct ttcaccggat caacgtgagc gaaggtacgg
    13621 gagagttcca gaatacccgg cagacgggat tcgagaactt ctttacccag gtggtcgagt
    13681 ttcagtttcg catgtggccc ccacggacca tcacagccgc gaccttcacg gatttcaatc
    13741 atgatggaac gcgccaccac gtcacggccc gccaggtctt tggcgttcgg cgcataacgc
    13801 tccataaagc gttcgccatg tttgttcagc agataaccgc cttcaccacg gcaaccttcg
    13861 gtgaccagta cgcccgcacc ggcaataccg gtcgggtgga actgccacat ttccatatcc
    13921 tgcaccggta cgcctgcgcg gatagccatg ccgacgccgt cgccagtgtt aatgtgggcg
    13981 ttagtggtgg actgataaat acgccctgcc ccgccagtcg ccagcacggt agcgcgggct
    14041 ttgaaataaa ccacttcacc agtttcgatg cacagtgcag tacaacccac caccgcgcca
    14101 tcctggtttt tcaccagatc cagcgcatac cactcggaga aaatagtggt gtggtttttc
    14161 aggttctgct gataaagggt atgcaacagt gcgtgaccgg tacggtcagc tgctgccgca
    14221 gtgcgtgccg cctgctcgcc gccgaagttt ttcgactgac cgccaaacgg acgttgatag
    14281 atacgaccat catcaagacg cgagaacggc aggcccatgt gttcgagttc cagaatcgct
    14341 tccggcccgg ttttacacat atattcaatc gcgtcctggt caccgatata gtccgaacct
    14401 tttacggtgt cgtacatatg ccattcccag ttatcttcat gggtattacc cagcgcaacg
    14461 gtaatgccgc cttgcgcaga aacggtatgg gaacgggtcg ggaagacttt agagagcagc
    14521 gcacaggttt gaccgctctg ggaaatttgc agcgccgcgc gcatacctgc gccaccggca
    14581 ccaatcacaa ctgcatcaaa ttctctgact ggcaatttca tcacacaccc cacaccacaa
    14641 cgaatccata aatcacgtaa accaccagag caacgacaat caccagttgc agcatcaggc
    14701 gcaaggccag cggtttaacg tagtcggtca acacctgcca catgccgatc caggcatgga
    14761 tcaagataga aaacagcgcc agcagggtga acactttggt gaacgcagag gcgaagaaac
    14821 cgatccagac ttcatatgtc agctcgccac tggtagcgaa aaaaccgacc atataaatga
    14881 tgtagagcgt caggacgata gcggtagcgc gaacgaggat gaaatcatgt acgccattgc
    14941 gtcctaatgc ggaggcgttg cttaccatac gaggactcct gcgagaagtg aaagcacgac
    15001 agtaataaca aaggagattt tggcggagcg tttacccgct tcgaatgttt cttccagata
    15061 gccaaaatcc atcatcatgt ggcgaatacc tacgacgacg tgatacgcca gagcggtaag
    15121 gatgccccac atgataaatt tgacgaagaa gctgcccata atcgcggaag cttgctcgaa
    15181 accttcaggg gaagagaggc tggtacccag aagccacagc aggataccca ctgcaataaa
    15241 ggtgatcaca ccggaaacgc gatggagaat ggacgctatc gccgtgatgg ggaaccggat
    15301 ggtctgtagg tccagattaa caggtctttg ttttttcaca tttcttatca tgaataacgc
    15361 ccacatgctg ttcttattat tccctgggga ctacgggcac agaggttaac tttctgttac
    15421 ctggagacgt cgggatttcc ttcctccggt ctgcttgcgg gtcagacagc gtcctttcta
    15481 taactgcgcg tcatgcaaaa cactgcttcc agatgcgaaa acgacacgtt acaacgctgg
    15541 gtggctcggg attgcagggt gttccggaga cctggcggca gtataggccg ttcacaaaat
    15601 cattacaatt aacctacata tagtttgtcg ggttttatcc tgaacagtga tccaggtcac
    15661 gataacaaca tttatttaat ttttaatcat ctaatttgac aatcattcaa caaagttgtt
    15721 acaaacatta ccaggaaaag catataatgc gtaaaagtta tgaagtcggt atttcaccta
    15781 agattaactt atgtaacagt gtggaagtat tgaccaattc attcgggaca gttattagtg
    15841 gtagacaagt ttaataattc ggattgctaa gtacttgatt cgccatttat tcgtcatcaa
    15901 tggatccttt acctgcaagc gcccagagct ctgtacccag gttttcccct ctttcacaga
    15961 gcggcgagcc aaataacaaa cgggtaaagc caggttgatg tgcgaaggca aatttaagtt
    16021 ccggcagtct tacgtaataa ggcgctaagg agaccttaaa tggctgatac aaaagcaaaa
    16081 ctcaccctca acggggacac aactgttgaa ctggatgtgc tgaaaggcac gctgggtcaa
    16141 gatgttattg atatccgtac tctcggttca aaaggtgtgt tcacctttga cccaggcttc
    16201 acttcaaccg catcctgcga atctaaaatt acttttattg atggtgatga aggtattttg
    16261 ctgcaccgcg gtttcccgat cgatcagctg gcgaccgatt ctaactacct ggaagtttgt
    16321 tacatcctgc tgaatggtga aaaaccgact caggaacagt atgacgaatt taaaactacg
    16381 gtgacccgtc ataccatgat ccacgagcag attacccgtc tgttccacgc tttccgtcgc
    16441 gactcacatc caatggcagt catgtgtggt attaccggcg cgctggcggc gttctatcac
    16501 gactcgctgg atgttaacaa tcctcgtcat cgtgaaattg ccgcgttccg cctgctgtcg
    16561 aaaatgccga ccatggccgc gatgtgttac aagtattcca ttggtcagcc atttgtttat
    16621 ccgcgcaacg atctctccta tgccggtaac ttcctgaata tgatgttctc cacgccgtgc
    16681 gaaccgtatg aagttaatcc gattctggaa cgtgctatgg accgtattct gatcctgcac
    16741 gctgaccatg aacagaacgc ctctacctcc accgtgcgta ccgctggctc ttcgggtgcg
    16801 aacccgtttg cctgtatcgc agcaggtatt gcttcactgt ggggacctgc gcacggtggt
    16861 gctaacgaag cggcgctgaa aatgctggaa gaaattagct ccgttaaaca cattccggaa
    16921 tttgttcgtc gtgcgaaaga taaaaatgat tctttccgcc tgatgggctt cggtcaccgc
    16981 gtgtacaaaa attacgaccc gcgcgccacc gtaatgcgtg aaacctgcca tgaagttctg
    17041 aaagagctgg gcaccaaaga tgacctgctg gaagtggcta tggagctgga aaacatcgcg
    17101 ctgaacgacc cgtactttat cgagaagaaa ctgtacccga acgtcgattt ctactctggt
    17161 atcatcctga aagcgatggg tattccgtct tccatgttca ccgtcatttt cgcaatggca
    17221 cgtaccgttg gctggatcgc ccactggagc gaaatgcaca gtgacggtat gaagattgcc
    17281 cgtccgcgtc agctgtatac aggatatgaa aaacgcgact ttaaaagcga tatcaagcgt
    17341 taatggttga ttgctaagtt gtaaatattt taacccgccg ttcaaatggc gggttaattt
    17401 ttatatgcct aaacacaaaa aattgtaaaa ataaaatcca ctatcggaca ttcatatatt
    17461 ctaaaaaaaa atatatcggt ataaattata aacaaatcga tgatttttaa tcatctatct
    17521 tcctctcagt tacatgaata aaccaccaaa tatagtgcac ccctataatt tccaatactt
    17581 tattcatcaa acatttaatt cataccatca attaattact tttacattta ataaaattaa
    17641 taatattttc aagaaaaact aaaaacattc gacaatcaaa taagatattc ttgcaccgat
    17701 atactttttt cttttctgtt aaaggactcc gttatgttta aaggacaaaa aacattggcc
    17761 gcactggccg tatctctgct gttcacagca cctgtttatg cggctgatga aggatccggt
    17821 gaaattcact ttaaaggtga agttattgaa gcaccgtgtg aaatacatca ggatgatatt
    17881 gataaagagg ttgaactcgg tcaggtgacc accagccaca ttaatcagtc acatcacagc
    17941 gatgccgttg ctgtcgacct gcgcttagtc aactgtgatc tggaaaactc cagcaacggt
    18001 tccggtggca agatttctaa agttgcagtc acctttgata gctcagcgaa aaccaccggc
    18061 gcagatccga ttctcaacaa caccagcacg ggtgaagcca ccggcgtcgg cgtacgttta
    18121 atgaataaag atcaaagcaa tatcgtttta ggcaccgcta ctccagatat cgacctggct
    18181 ccgacctcca gcgaacaaac gctgaatttc tttgcctgga tggaacaaat tgatcaggct
    18241 acacctgtaa cgccaggcgc agttacggcg aatgcaacct acgtgctgga ttataaataa
    18301 gtattacttt ggcggcgcta tcgccgcctt tcataaaata tttatcaggt atggacaccg
    18361 tgaatattta tcgactctct tttgtatcct gcctggtcgt ggcgatgcct tgcgcattgg
    18421 cggtcgaatt caaccttaat gttctcgata aatcaatgcg cgaccgcatt gatatttcat
    18481 tattaaagga aaaaggagtc attgctcccg gtgagtattt tgttagcgtt gcggtaaata
    18541 ataaccaaat cagtaacggg caaaagatta actggcacaa aaatgacgat aaaaccattc
    18601 cgtgcatcaa tgatttactg gtcgataaat ttggcttaaa acctgaagtc cgtcagtcgt
    18661 taccattgat aaatcagtgc gtcgatttta gctcccgacc tgaaatgctc ttcaatttcg
    18721 atcaagccaa tcagcaacta aatatcacca ttccgcaagc ctggctggcg tggcactcag
    18781 aaaactgaac cccaccctcc acatggaaag aaggtgtcgc cggtgtcctg atggattaca
    18841 acttgtttgc cagcagctac cgcccacagg atggcagcag cagcactaat cttaacgcct
    18901 atggaacagc cggaatcaac acgggggcat ggcgcttacg cagtgattat cagttgaatc
    18961 agactgatag cgatgataac catgaacagt caggcgaaat atcacgtacc tatctttttc
    19021 gcccgttacc gcaattaggt tcaaaattaa ccctcggcga aacggatttt agttccaata
    19081 ttttcgacgg tttttcttat accggcgcgg cactggcaag tgacgatcga atgttgccat
    19141 gggaactacg cggctacgcc ccacaaatta gcggtattgc acagaccaat gccacggtga
    19201 cgatcagtca atcaggccgc gtcatttacc agaaaaaagt cccaccaggc ccatttatca
    19261 ttgacgacct taatcagtct gttcagggca cactggatgt caaagtgacg gaagaagatg
    19321 gtcgggtgaa caatttccag gtttcggcag catcgacgcc cttcctgact cgtcagggac
    19381 aggttcgcta taaactggcc gcgggtcagc cacggccctc catgtcacat caaactgaaa
    19441 atgaaacctt ttttagcaat gaagtttcct gggggatgct gtcaaacacc tcgctgtacg
    19501 gcggcctgct gctttctggt gatgactacc attctgccgc aatgggtatt gggcaaaata
    19561 tgctgtggct tggtgcgctg tcgtttgatg tcacgtgggc cagtagccat tttgatactc
    19621 agcaggacga gcggggctta agctaccgtt ttaattacag caaacaagtg gatgccacta
    19681 acagcacgat ttccctcgcc gcttatcgtt tctccgatcg tcattttcac agctacgcca
    19741 actatctgga tcacaaatac aacgacagcg atgcgcagga cgaaaaacag acgatcagct
    19801 tatctgtggg ccaaccgatt accccactaa acctcaatct ttacgccaac ctgctacatc
    19861 aaacctggtg gaatgcagac gcctccacga ccgccaacat cacggcaggt tttaatgttg
    19921 atattggtga ctggagagat atctctattt cgacgtcatt caatacaacc cattacgaag
    19981 ataaagatcg cgacaaccag atttacctgt cgatttcgct ccccttcggt aacggtggtc
    20041 gggttggcta tgacatgcaa aacagtagcc acagcaccac acaccgcatg tcgtggaacg
    20101 atacgctgga tgaacgtaat agctggggca tgtctgccgg actgcaatcc gaccgtcctg
    20161 acaatggagc ccaggtgagc ggtaactatc agcacctgag ttcagcgggt gagtgggata
    20221 tttctggtac ctatgccgcc aatgattaca gttccgtcag cagcagctgg agcggttctt
    20281 tcaccgcaac ccaatatggt gcagcgtttc atcgccgcag ctccaccaat gaaccacgcc
    20341 tgatggtcag caccgatggc gtggcagata ttccggttca gggcaatctc gactacacca
    20401 accattttgg cattgcggtg gtgccgttga tttccagtta ccagccttcc accgtggcgg
    20461 tgaacatgaa tgacttaccc gacggcgtaa cagttgcaga aaacgttatc aaagaaacgt
    20521 ggattgaagg cgcgataggt tacaaatcac tggcttcccg ttccggtaaa gacgttaacg
    20581 tcatcattcg caacgccagc ggtcagtttc ctcccctcgg agcggatatc cgccaggatg
    20641 acagcggcat tagcgtgggg atggttggcg aggaaggaca tgcctggtta agcggagtcg
    20701 ctgaaaatca aaagtttacc gtggtctggg gtgatagcca gcattgctcg ctccatcttc
    20761 ctgaacatat ggaagacacc gcaaatcgcc tgattttacc ttgtcattaa ttaaggaaat
    20821 gaaaatgaca tttatgaaag gactacccct tttgttgttg gttgccagtc tgtgcagcca
    20881 cgctgcacta caacccgatc gcactcgtat tgtgtttaac gctaatgata aagctaccag
    20941 tctgcgggtg gataatcgta gcgataaact cccctacctc gcttattcct ggctcgaaaa
    21001 tgaaaaaggg gagaaaagcg atgatcttct ggtcgccctg ccgccgatac aacgtctgga
    21061 accgaaagca acaacgcagg tacggatagt aaagcaagcc tcgaccacaa aattaccggg
    21121 cgatcgcgaa acgctatttt tctacaatat gcgtgaaatt cctcccgccc cggaaaaaaa
    21181 cagcgaccat gccgttctgc aagtcgccat tcagagtcgt atcaaggtgt tctggcgacc
    21241 ggctgcatta cgcaagaaag caggagaaaa ggtcgaactg cagttacagg tcagccaaca
    21301 gggcaaccaa ctgacactga aaaatcctac cgcgtattat ctgaccattg cctacctggg
    21361 acgaaatgaa aaaggcgttc tccccggctt caaaaccgtg atggttgcgc cttttagtac
    21421 ggtcaacaca aacaccggaa attatagcgg cagccagttt tatctcggtt atatggatga
    21481 ttacggcgcg ttacgcatga cgacgctcaa ctgcagcgga caatgccatt tacaagccgt
    21541 ggaggcgaag aaatgagtgc tggcaaggga gtgttgctcg tcatctgtct gttatttctg
    21601 ccgttgaagt ctgcgcttgc cctgaactgc tactttggtt catccggtgg ctcggtagaa
    21661 aaatcagaag cgattcaacc ttttgctgta ccaggcaatg ccaaactcgg cgataagatt
    21721 tgggaatctg acgatattaa aattcccgtc tattgtgaca acaataccaa cggcaatttt
    21781 gaaagtgagc atgtttatgc ctgggtaaac ccctacccgg gggtgcagga tcgctattat
    21841 caactcggcg taacttacaa tggcgttgat tatgacgcca accagggaaa aagccgcatc
    21901 gacactaacc agtgtattga cagtaagaac attgacattt atacccctga gcagattatc
    21961 gcgatgggat ggcagaacaa aatttgctcg ggtgatcccg ctaatattca catgtcacgt
    22021 acctttctcg ctcgcatgcg gttatacgtc aaaatacgag aaatgccgcc gcatgattat
    22081 caaagtacgc ttagcgacta tatcgtcgtg caatttgacg gtgccggtag cgttaacgaa
    22141 gatcctactg cccaaaacct gaaatatcat attaccggtc tggaaaacat tcgcgtgctg
    22201 gattgcagcg tcaatttttc catttcaccg gaaacacagg tgattgattt tggtaaattt
    22261 aatttgctgg atattcgtcg ccacacaatg tcgaaaacat tcagtattaa gacgacaaaa
    22321 tcacaaaatg accaatgcac cgacggattt aaagtcagtt cctcctttta taccgaagaa
    22381 acgttggttg aagaagataa agcattgttg attggtaatg gtctgaagct acgtttgctg
    22441 gatgaaaacg cctcgcctta taccttcaat aaatatgctg aatacgccga tttcaccagc
    22501 gacatgttgg tctacgaaaa aacctataca gctgaacttt cgtccattgc aggtaccccc
    22561 atcgaggctg ggcccttcga tacagtggtg ctttttaaaa ttaactataa ctgatttgcc
    22621 atgatgccct ttgcagccgg aaagggcatc tctttcagaa aattgctgat tttccccttt
    22681 tccttgattg ctgttatttt ttcctggccc ggctttcttt atgctgtatc gatacaccaa
    22741 agagaaaata atgagggagc gaaggatgcc agttttgcag tggggaatgt tatgtgtgct
    22801 atcacttctc ctttctattg gtttcctcgc ggtacatctc ccggcggcgc tattacttgg
    22861 gccgatgatc gccgggatca tcttcagtat gcgcggaatt actctgcaac ttccccgctc
    22921 cgcttttctc gccgcgcagg ccattcttgg ctgcatgatt gcgcaaaacc tcactggttc
    22981 gattctcacc acgctggccg ccaactggcc gatcgtgctt gctattttac tggtgacgct
    23041 gctttccagc gccatcgtgg gttggttatt ggtgcgctat agctcactgc ctggaaatac
    23101 cggtgcctgg ggttcttctc caggcggcgc agcggcaatg gtcgctatgg cgcaagatta
    23161 cggcgcagat attcgcctgg tggcgtttat gcaatatctg cgagtgctgt tcgtcgcggg
    23221 ggcagctgtt ctggtcaccc gcatgatgct gggtgataac gctgaagcgg ttaaccagca
    23281 aatcgtctgg ttcccgccag tgagcattaa tctcctgctt acgattttgc tcgcagtcgt
    23341 tgccggtacg gcgggatgca tgctgcgtct tccttccggc acgatgctca tcccgatgct
    23401 ggcgggcgca gtgctccagt ctggtcagct catcaccatc gaactcccgg aatggttgct
    23461 ggcgatggcg tatatggcaa ttggttggcg gattggtctt ggtttcgata aacaaatctt
    23521 actgcgggca ttgcgcccac tgccacaaat cctgctgtcg atttttgctc tgctggctat
    23581 ttgtgcgggt atggcgtggg ggctgacccg gtttatgcac attgatttta tgactgccta
    23641 cctcgccacc agtcccggcg ggcttgatac cgtggcggtc atcgccgcag ggagcaatgc
    23701 cgatatggcg cttattatgg cgatgcaaac cctgcgcctg ttcagtattt tgctgacggg
    23761 gccagccatt gcgcggttta tttcaaccta tgcgccgaag cggtcggcct agtgctggca
    23821 gcctggacac cagtaaaacg ggcgcgagga caacgtggtt ttctcaatga tgccgccaca
    23881 gcgttcgcac agttcgccat cacgatgaaa aaccttaaag cgaaacagcg ccccatgatg
    23941 cttattctca tccacctgcc cccgcgtagc gtaagaaaac cgaggaatct ccagtaacgc
    24001 gtgtgcgagt gcatccagtt gcgccgcatt gagatctttc gctttatgat ttccagtcaa
    24061 cccaacctgc cagaggatct ccacccgcaa ataattgcca agcccagcca gaaacgcctg
    24121 atcgagcagt aatcctgcaa actgacggtt acgaaagcgc ggtgacaata accgttcctt
    24181 taccacctcc ggcgtcagat tcggatccag cacatcggga ccaacgcgtt gtaaaaacgg
    24241 atgcgtggtc agttgttccg gcctcaacat ctcaatatcc gaggcgctat aaagcagaat
    24301 ggttttgtca gccgtttgca gttttacccg caatactcgc gtggtctgcg gctcttcgcc
    24361 ggtatcaacc acgcgccaga cgccgtaaag ctgattatgg ctgtagagcg ttaagtcgtt
    24421 ggaaaaatga gttaacaacg ccttaccacg cgtttccaca tgggtaacgt gttgaccgat
    24481 aagttgtgat tgataagttt ttaactgcgg gaaggcaaac cagacatcag ttagtggttt
    24541 gcctttgatc gccgcctcca ggttatccgc tgcacggcgg atctccgggc cttcaggcat
    24601 ggtgatatcc ttttttcatt ctttattaat cggggttatg ctgcgacaac aatctccttt
    24661 tcggcaaatg tagagcgtag tcggcgggcg aacgccagtg cgtgctcgcc gtcgccatgc
    24721 aggcagactg tttgcgccgt gaccgttgcc cattcgccgg tgatactttt gactctgccg
    24781 tgttgcacca tctccagcgt ttgcgccaac gcctgttctt cgttttcaat caacgcgcct
    24841 cgctgacttc gcggcaccag cgagccgtca gcctgataac cgcgatcggc aaacacttcc
    24901 tcgcgcgttg tcaggccata ttgcttgcct gcacgaatca gctcgcttcc tgccagccca
    24961 acgagaatca atgccggatc gcaagcgtat accgctctgg cgatggcgtc tgccagttgt
    25021 gcttctttcg ccgcctggtt gtacaacatg ccgtgcggtt tgacatgacg cattacgccg
    25081 ccttgcgcac gggcaatcgt tgccagcgcg ccaatttgat acagcgtctg ggcgtaaacg
    25141 gtttctggcg gcagctgcat ggcgctgcga ccaaaatttt ccctgtcggg aaaactcggg
    25201 tgagcgccaa tcgcgacacc attttttatt gcttcacgca cgcaagcctg catgatttgc
    25261 gcatcgcctg catgaaatcc acaggcaata ttggcagagg aaaccagcgt taatagctct
    25321 gcgtcgctgg cgcagccttc gcccagatcg gcgttcaggt caattttcat tgtgcagccg
    25381 ccacgctaat tgttcgaaat aacgttgctg atcttgccgc gctttcagtg cctcttccag
    25441 tgaacactgg acaaaatgaa tcggctgacc gagcggaatt tgcgccagat ggtacatatc
    25501 agcctcaatg atacaggcaa tacgcgggta accaccggtg gtctgtgcgt cgttcatcaa
    25561 cacaatcggc tgcccgttat gcggcacctg caccacgccc ggtaacaaac cgtgagataa
    25621 cagttcgcga tcggtgatgc gttttaaaat ttgcccctgt aagcgatagc ccattcggtt
    25681 actttgcgag ctaagctgcc agggcgaacg ccagaatgca tcctgcgagg cgcgatcgaa
    25741 ctcatgatat tccggccccg gcaaggcgcg aatgcggttg ccccacagca gctgtttaac
    25801 gccctgcgct tccataaaat cacgcttcga tttgccaatc gggagtcggt caccatcctt
    25861 cagtaaacgg ccttccagcc cgccaatccc cactttgaga tcggtgctgc atgaccccat
    25921 taccggcgga acatcaatac cacccgcgac cgccagataa ctgcgcatcc cgtgctgcgg
    25981 gcgtttaagc gttaaacgct ggcctgcttt catcggcaat cgccagccgg tccagacggc
    26041 attatcatcc agccgcgctt cgcaaccggc acccgtcaga gcaaaccacc catcagtttc
    26101 gaactcaacc gttaactgac cgagcgtgat ctccagcgcg ggggcattgg cgtcattacc
    26161 caccagcagg ttagcaatgc gtaacgcagg catatccagt gcgccgcagt ggctgatacc
    26221 cgactggcga aaaccgtgac gaccgccatc ttgcacagtg gtatacatgc ccgcacgaat
    26281 aatcttcagc atactccctc cttttgcggt acaaagcgca cgctgtctcc cggacgtaat
    26341 aagatgggtt cgtcacgcgc cggatcaaac aggctgagtg aggtatgacc aatcaactgc
    26401 cacccacccg gcgttgccag cggataaaca ccagtctgcg gcccgccgat cccgacagaa
    26461 cctgccggaa cgagcaagcg cggttcagcg cgccgtggcg tgtgtagttg ttccggcaaa
    26521 ctcccgagat acgggaagcc cggttgaaaa cctaaaaacc agaccacgta ttccacggag
    26581 gagtgcaatt caacaacctg tttttcgctc aacccgcaat gcgccgcgac caccgccaaa
    26641 tccggtccgc ctgcaccacc gtaaaccacc ggaatttcaa taaagcgaga ctcaggttcc
    26701 agggcctcgc tctcctccca ccagcgttgc aaacgctcta tggcatccag cgccagcgac
    26761 tcaggattac gcaaaatcac cgtgatattg ttcatgccgg gaatggcttc aaccacattc
    26821 ggcatatcca ccagacgctg cgccagtcgc cagatccgtt tctggctagc cagcgtcacc
    26881 ggcggttcca gttccagcac taccgccgtt tcacctatca gataacaacg cgctcgttgc
    26941 actttcgatc cctctgatta ttcgttatgc aggattaggt atatcaataa aggtcacatc
    27001 aagatcggta ttttcattca gccactcact caatgcgcga ataccaccgc gttcagtggc
    27061 atggtgacct gcagcataaa aatgcaatcc ctgctcgcgg gctgaatgaa tggtctgttc
    27121 agaaacttcg ccagtaataa aagcatccac gccaaaacgc gcggcgctat cgataaaact
    27181 ttgcccgccg cccgtgcacc aggcgacgcg ctggaccacc tcaggtccgg tatcgccaca
    27241 ccataacggc ttacgtccca gacgcgcttc aatccaggag gctagttcca gtcccggcac
    27301 aggcatggtc agctctcccc acggcaccaa cggctcaatt tcgcccatga ccgtgatccc
    27361 cagtaacgcc gccagctgtg cgttattgcc cagctcagga tgtgcgtcaa gcggcaaatg
    27421 ccagccatac aggttgatat cattcgccag caacgttttt aaacggttac gcttcattcc
    27481 gcgaatgacc ggagactctc ctttccagaa gtagccatga tgcacaatga ccgcatccgc
    27541 gcccagacgc actgcctcat cgagcaaagc ctggctggcg gtgacaccgg taacaatttt
    27601 ttgcaccgtc tctttgcctt ccacctgcaa accattcggc gcgtaatcac taatcgccgc
    27661 gctgttcagt ttttcgttaa tcagttgttc cagttcggtg tttttcatct tcgcgccttc
    27721 cgtattctga tagctacacc gttaacatag cgttacctcg cctgttcgtc gatagccaat
    27781 cttttgacat attaagaaac aaacccgacg ccaaaagacg caaattgttt atatcatcac
    27841 gcttcagcta atgtatattt atgcaatcag acagcatatt gcataaataa tcagatctgt
    27901 atcaaagttt taactttaag gaaacacaag cacgccgcgc aactattacg tgacgttgcc
    27961 gtcaattgtg gaattattat gaataaacac gcatcacaac cgcgcgctat ttactatgtc
    28021 gttgcgctgc aaatctggga atattttagc ttttacggca tgcgtgccct gctgattctc
    28081 tatctcacca atcaactaaa atacaacgat actcacgcct acgagttatt tagcgcctac
    28141 tgttcgctgg tgtatgtcac gccaatcctc ggtggctttt tggcggataa agttctcggc
    28201 aatcgcatgg cggtgatgct gggggcgttg ttgatggcga tcggtcatgt ggtgctgggt
    28261 gccagtgaga tccatccgtc attcctctat ctgtccctgg cgattatcgt ttgtggctat
    28321 ggtctgttta aatccaatgt cagttgcctg ctcggcgagc tgtatgagcc aaccgatccg
    28381 cgtcgtgatg gcggtttctc gctgatgtat gcagcgggta acgtggggtc tattatcgca
    28441 cctatcgcct gtggttacgc ccaggaagag tacagctggg cgatgggctt tggcctggcg
    28501 gcggtgggta tgatcgcggg tctggtcatt ttcttatgtg gcaatcgtca tttcacacat
    28561 acccgcggcg ttaataaaaa agtactgcgt gcgacaaact ttctcctgcc taactgggga
    28621 tggctgctgg ttctgctggt ggcaacgcct gcgctgatta ccgtattgtt ctggaaagag
    28681 tggtcggtat acgccttaat tgtcgcgact attattggcc tgggtgtact ggcaaaaatt
    28741 tatcgcaaag cagaaaacca gaaacagcgt aaggagctgg ggctgattgt gacgctcacc
    28801 ttcttcagta tgttgttctg ggccttcgca caacagggcg gcagctcgat tagcctttat
    28861 atcgaccgct tcgttaaccg cgatatgttt ggttataccg ttccgactgc tatgttccag
    28921 tcgattaatg ccttcgcagt tatgctgtgc ggtgtgttcc tggcgtgggt ggttaaagaa
    28981 agcgtcgcag gtaatcgtac cgtgcgcatc tggggaaaat ttgctcttgg tctcggcctg
    29041 atgagcgccg ggttctgcat tctgacctta agcgcccgct ggtcctcaat gtatggtcac
    29101 tcttctctgc cactgatggt attaggcctg gcggtgatgg gctttgcgga actgtttatc
    29161 gacccggttg ccatgtcgca aattacgcgc attgaaatcc ccggtgtgac cggcgtatta
    29221 accggcattt atatgctgct ttccggcgcg attgcgaact atctcgcggg cgtgattgcc
    29281 gatcagacat cgcaggcttc gtttgatgct tccggggcga tcaactactc catcaatgca
    29341 tatattgaag tatttgatca aattacctgg ggcgcactgg cgtgtgtagg actggtactg
    29401 atgatttggc tgtatcaggc gctgaaattc agaaaccgcg cgctggcgct ggaatcttaa
    29461 taggccagca ccatacctga taaaacgctc gctgcgtttt atcaggctcc tttcctcgct
    29521 tcttcgtacg ctgccagcgt tcgcagcctt gcctctttgt gatcaactat cggttgcgga
    29581 taatccagca tcacacctgc tttctgcgcc cacttccacg gctcatgcac cgctttccct
    29641 ggtacatcgc gcagctccgg taaccatcgg cggataaact cgccctcacg gtcaaatttc
    29701 tcgccctgag ttatcggatt gaaaatacga aaatacggcg cagcatcagt acccgtagaa
    29761 gccgcccact gccagccacc gttattagct gccaaatcac catcaatcag ctgcgacatg
    29821 aaatatcgct cgccttcgcg ccagtcgatc aacaaatctt tcaccagaaa actggctgta
    29881 atcatccgta gccggttatg catccagcca gtactgttaa gctgacgcat agcggcatca
    29941 acaatcgggt atcccgtttt gcctttctgc caggcctgta aatgtgcggg attgctttgc
    30001 cactgcacac gatccgtcca ggcaataaac ggacaatgtt tacacaacga ggggtaatac
    30061 gtcatcagat gacggtagaa ctcgcgccag atcagctcac taagccagac actaccggcc
    30121 ccaccgtcca gcgcctgcgg ctgttccgcc aacaagcgat gcaaacactg gcgaggcgat
    30181 aacccgcccg ttgccaggct ggcggacaaa cgactggtgc cttccactgc cggaaaatct
    30241 cgttgttgct catattctcc ggcaccgttc tggcaaaact ggcgtaattg cgcaatcgcc
    30301 gctttttctt ccaccgggaa atgcgcagta tcgaaagact gacgaggata attcagcgta
    30361 atggatggcg cgggctctat cgatccgcta ctacgaactt ttggcgcagc gacacactcc
    30421 ggcatccctt cccgcagccg tttcagccag gcattcttaa aaggcgtaaa gactttgtac
    30481 atctcgtgat taccggtcat caccgcgcca ggcggcagga tcacgctgtc atcaaatcct
    30541 tcacacacca cgttacgcag cgctctttca acttccacat cccgcgcccg ctcattcact
    30601 tcatactgat agttataaaa caggtgggta acgctgtttt ccgcgcacac ctgtttaact
    30661 atttcgacac tggcgacaaa gtcatccact tcacggaaca ataaaggaat acctttttcc
    30721 gcaagcgcta tttgtagccc attcagttga gcattgataa gttcagcctg acgcggcgac
    30781 atgttatgcg tcgcccactg gcgtggtgta gcgatatata acgccagcac gcgtgcagac
    30841 gaattgcggc aggcggcagc cagtgcgaga ttatcgtgca gacgtaaatc ctggcgaaac
    30901 cagaccagat gggtaatcat aaaactcctg aatggcgcaa gttaatcaca cgcggccaaa
    30961 gttcgaaata acgctgccct gaaagccagg cgtcaggata aagcgccata tagtgtttga
    31021 tacgcatcag cggcgcaaga agtggttgct cgccacggcg ataactgtcg ataagcgccg
    31081 ccaactgctg gcgttctgtg gaatcaatat gcgggcgaaa ataaccctga acgtgcatca
    31141 aaacgttggt gtgatcgcgc gggttggcgg gatgagaaag caaaacaatt acgcgttggt
    31201 agtactggtt gtaaaaatca tccagatttt gccactggtg aatatcagcc acgaacgggc
    31261 caagtttgcg gtactccggc tgagaatgcg ccagaaagac gagtttatag cggctgtgat
    31321 aatcgagaag cgccccgcgc gttaagccat gttctttcag tcgatgtaac tcatgaaggg
    31381 cgaagatacg gattagggtg ctgtcatcaa atcgttgctg attcattact gctcctgaac
    31441 ggtttacagg agtaagtgta gacgttgaga aatgatattt gtgaagttaa tcctgttgta
    31501 gcaggacaaa tttacgaaag cctgctcccc gcaaggactg acgtcaggta gtttctaacc
    31561 atagctgccc tttctattca aacgtgaaat caataagctc atcagggaca tcgcaaacaa
    31621 tatgaagacg ggtttcttct ctgccgtgac tcttttcact aattgcgtaa ctgtcatgct
    31681 tgggattatt taattctttc agcggaaatt tttcctcgaa ggctttattt agccgcccct
    31741 ggtttccttt tacagcgaat aaataatcac ctccctgttt ttgtatcttc tctgcaatat
    31801 ctttctggca acccatcgca tcggttgtga tgatttttcc tttaatatcc agcatgttaa
    31861 gaagttcagg gatagctgtg atctcattgg atttcttatc cgtcttgatc tgcccgatga
    31921 ccagactgtg cattgttgag aacgcactaa tgacatgaat cgctcccctg cggcgactct
    31981 tgtcataaga gtgccggagc gtttttccat caattgcaat gacgtcttta tcatttgatg
    32041 aatggcaatc acgcatccag ttaataaagc actcgtgaaa ttttgcagga ctgatacagg
    32101 atacaactct ggcaatagta tcgtgaacag gaataccatt ttcaaaatca ccatattgct
    32161 tcaagaaatc gagatgtgtt tcccc
//
LOCUS       DAZUDJ010000056        31993 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.056, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000056 DAZUDJ010000000
VERSION     DAZUDJ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31993
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.056"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(415..1788)
                     /gene="argH"
                     /locus_tag="ACHY1N_003416"
     CDS             complement(415..1788)
                     /gene="argH"
                     /locus_tag="ACHY1N_003416"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HFS4045657.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     ASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDT
                     WLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEDLPLDELQKFSPVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIA
                     FAQARLE"
     gene            complement(1849..2625)
                     /gene="argB"
                     /locus_tag="ACHY1N_003417"
     CDS             complement(1849..2625)
                     /gene="argB"
                     /locus_tag="ACHY1N_003417"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418394.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HFS4045658.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGL
                     FLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKV
                     NAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA"
     gene            complement(2633..3637)
                     /gene="argC"
                     /locus_tag="ACHY1N_003418"
     CDS             complement(2633..3637)
                     /gene="argC"
                     /locus_tag="ACHY1N_003418"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HFS4045659.1"
                     /translation="MLNTLIVGASGYAGAELVTYVNRHPHMNITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDISEFSPGVDVVFLATAHEVSHDLAPQFLEAGCVVFDL
                     SGAFRVNDATFYEKYYGFTHQYPELLEQAAYGLAEWCGNKLKEANLIAVPGCYPTAAQ
                     LALKPLIDADLLDLNQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     ATHLGADVIFTPHLGNFPRGILETITCRLKSGVTQAQVAQVLQQAYAHKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIIVATEDNLLKGAAAQAVQCANIRFGYAETQSLI
                     "
     gene            3791..4942
                     /gene="argE"
                     /locus_tag="ACHY1N_003419"
     CDS             3791..4942
                     /gene="argE"
                     /locus_tag="ACHY1N_003419"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HFS4045660.1"
                     /translation="MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFK
                     DLGFNVEVQPVPGTRNKFNMLASIGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHD
                     GKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTAL
                     RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQ
                     LRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNG
                     LLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEA
                     PFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH"
     gene            5294..7945
                     /gene="ppc"
                     /locus_tag="ACHY1N_003420"
     CDS             5294..7945
                     /gene="ppc"
                     /locus_tag="ACHY1N_003420"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HFS4045661.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKS
                     SRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQ
                     LDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKAT
                     DLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARL
                     KGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAE
                     TREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKEL
                     RNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKE
                     GQEPDPRVEQALMVTIAGIAAGMRNTG"
     gene            8128..9861
                     /gene="eptC"
                     /locus_tag="ACHY1N_003421"
     CDS             8128..9861
                     /gene="eptC"
                     /locus_tag="ACHY1N_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HFS4045662.1"
                     /translation="MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTN
                     GIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLF
                     VMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
                     YGLILHPIAMNTFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNE
                     NNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPNLT
                     VFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSKQTDKQFYMNQQRTQSAREYDTNVLKPFQEVLKDPAPKKLIIVHLLGT
                     HIKYKYRYPENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAA
                     NPNGFLVYFSDHGEEVYDTPPHKTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFS
                     QDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            10010..10861
                     /gene="yijO"
                     /locus_tag="ACHY1N_003422"
     CDS             10010..10861
                     /gene="yijO"
                     /locus_tag="ACHY1N_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFS4045663.1"
                     /translation="MYHDVSYLLSRLINGPLSLRQIYFASSNGPAPDLAYQVDFPRLE
                     IVLEGEFVDTGAGATLVPGDVLYVPAGGWNFPQWQAPATTFSVLFGKQQLGFSVVQWD
                     GKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQPQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EKPTTPE"
     gene            complement(10848..11189)
                     /gene="frwD"
                     /locus_tag="ACHY1N_003423"
     CDS             complement(10848..11189)
                     /gene="frwD"
                     /locus_tag="ACHY1N_003423"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HFS4045664.1"
                     /translation="MAYLVAVTACVSGVAHTYMAAERLEKLCQLEKWGVSIETQGALG
                     TENRLADEDIRRADVALLITDIELAGAERFEHCRYVQCSIYAFLREPQRVMSAVRKVL
                     SAPQQTHLILE"
     gene            complement(11191..12069)
                     /gene="pflC"
                     /locus_tag="ACHY1N_003424"
     CDS             complement(11191..12069)
                     /gene="pflC"
                     /locus_tag="ACHY1N_003424"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418387.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[formate-C-acetyltransferase]-activating enzyme"
                     /protein_id="HFS4045665.1"
                     /translation="MTSSAGQRISCNVVETRRDDVARIFNIQRYSLNDGEGIRTVVFF
                     KGCPHLCPWCANPESISGKIQTVRREAKCLHCAKCLRDADECPSGAFERIGRDISLDA
                     LEREVMKDDIFFRTSGGGVTLSGGEVLMQAEFATRFLQRLRLWGVSCAIETAGDAPAS
                     KLLPLAKLCDEVLFDLKIMDATQARDVVKMNLPRVLENLRLLVSEGVNVIPRLPLIPG
                     FTLSRENMQQALDVLIPLNIRQIHLLPFHQYGEPKYRLLGKTWSMKEVSAPSSADVAT
                     MREMAERAGFQVTVGG"
     gene            complement(12035..14332)
                     /gene="pflD"
                     /locus_tag="ACHY1N_003425"
     CDS             complement(12035..14332)
                     /gene="pflD"
                     /locus_tag="ACHY1N_003425"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFS4045666.1"
                     /translation="MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRA
                     KATAYILEHVEISIRDEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFA
                     ISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIID
                     YPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCT
                     DAQRREELLTIAEISRHNAEHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYM
                     LPFYQASLTQGEDPAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT
                     ENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRLGTGIPQIF
                     NDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN
                     EGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR
                     DITDGGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGE
                     KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVP
                     LGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVK
                     FTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA
                     GYSAFFVELSKEIQDDIIRRTAHQL"
     gene            complement(14383..14703)
                     /gene="frwB"
                     /locus_tag="ACHY1N_003426"
     CDS             complement(14383..14703)
                     /gene="frwB"
                     /locus_tag="ACHY1N_003426"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HFS4045667.1"
                     /translation="MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIG
                     LENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHL
                     AQTA"
     gene            complement(14718..15797)
                     /gene="frwC"
                     /locus_tag="ACHY1N_003427"
     CDS             complement(14718..15797)
                     /gene="frwC"
                     /locus_tag="ACHY1N_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HFS4045668.1"
                     /translation="MNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGA
                     VPDAVADPNLKKLFDIGVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAG
                     FFGALIAGIIGGIVVHYLKKIPVHKVLRSVMPIFIIPIVGTLITAGIMMWGLGEPVGA
                     LTNSLTQWLQGMQQGSIVMLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAI
                     AAVGICIPPLGMGLATLIGRKNFSAEERETGKAALVMGCVGVTEGAIPFAAADPLRVI
                     PSIMVGSVCGAVTAALVGAQCYAGWGGLIVLPVVEGKLGYIAAVAVGAVVTAVCVNVL
                     KSLARKNGSSTDEKEDDLDLDFEIN"
     gene            16106..18607
                     /gene="ptsP"
                     /locus_tag="ACHY1N_003428"
     CDS             16106..18607
                     /gene="ptsP"
                     /locus_tag="ACHY1N_003428"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFS4045669.1"
                     /translation="MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRK
                     GNAKSALALIGTDTLAGDNCQLLISGADEQEAHQRLSQWLRDEFPHCDAPLAEVKSDE
                     LEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALGNLPAAKGVDAEQSALE
                     NGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLREHLLAGVSAGLSCAEAIVTS
                     ANHFCEEFARSSSSYLQERALDVRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELT
                     PSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDIDALTPWQHQTIYIDG
                     NAGAIVVEPGEAVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVE
                     AQAAFGNGAEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGG
                     DKPVDYLNIPAEANPFLGYRAVRIYEEYASLFTTQLRSILRASAHGSLKIMIPMISSM
                     EEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIDQCCEEIDFFSIGSN
                     DLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVL
                     PLLVGLGLDELSMSAPSIPAAKARMAQLDSRECRKLLNQAMACRTSLEVEHLLAQFRM
                     TQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGRCRYPRKLEADLWAREAVFST
                     GLGFSFAIPHSKSEHIEQSTISVARLQAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIF
                     SRLARRIMHEEFRNALVNAASADAIASLLQHELEL"
     gene            18619..19281
                     /gene="fsa"
                     /locus_tag="ACHY1N_003429"
     CDS             18619..19281
                     /gene="fsa"
                     /locus_tag="ACHY1N_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFS4045670.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIIAASKESIWEVLP
                     RLQKAIGDEGILFAQTMSRDAQGIVEEAKRLRDAIPGIVVKIPVTSEGLAAIKMLKKE
                     GITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPES
                     MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTT
                     HL"
     gene            19292..20395
                     /gene="gldA"
                     /locus_tag="ACHY1N_003430"
     CDS             19292..20395
                     /gene="gldA"
                     /locus_tag="ACHY1N_003430"
                     /EC_number="1.1.1.6"
                     /EC_number="1.1.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418380.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional L-1,2-propanediol
                     dehydrogenase/glycerol dehydrogenase"
                     /protein_id="HFS4045671.1"
                     /translation="MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFA
                     QSTVEKSFKDAGLVVEIAPFGGECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTAKA
                     LAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMVIVDTKIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENAPVEEIETVAALSHAVGLPITLAQLDIKEDVPAKMRIVAEAACAEGE
                     TIHNMPGGATPDQVYAALLVADQYGQRFLQEWE"
     gene            20670..21287
                     /gene="yijF"
                     /locus_tag="ACHY1N_003431"
     CDS             20670..21287
                     /gene="yijF"
                     /locus_tag="ACHY1N_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1287 domain-containing protein"
                     /protein_id="HFS4045672.1"
                     /translation="MKASLALLSLLTAFTSHSLKSPAVPPTVVQIQANTNLAIADGAR
                     QQIGSTLFYDPAYMQLTYPGGDVPQERGVCSDVVIRALRSQKVDLQKLVHEDMAKNFA
                     EYPQKWQLKRPDSNIDHRRVPNLETWFTRHDKTRPISKNPSDYQAGDIVSWRLDNGLA
                     HIGVVSDGFARDGTPLVIHNIGAGAQEEDVLFSWRMVGHYRYFVK"
     gene            complement(21314..22219)
                     /gene="yijE"
                     /locus_tag="ACHY1N_003432"
     CDS             complement(21314..22219)
                     /gene="yijE"
                     /locus_tag="ACHY1N_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine transporter YijE"
                     /protein_id="HFS4045673.1"
                     /translation="MSAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTAL
                     RCIFGALVLFIVLLLRGRGMRPTPFKYTLAIALLQTCGMVGLAQWALVSGGAGKVAIL
                     SYTMPFWVVIFAALFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAMLAILS
                     GVSWGASAIVAKRLYTRHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTVFW
                     ALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGS
                     GIVLIVLALALVSRKKKEAVSVKSI"
     gene            complement(22313..24493)
                     /gene="katG"
                     /locus_tag="ACHY1N_003433"
     CDS             complement(22313..24493)
                     /gene="katG"
                     /locus_tag="ACHY1N_003433"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004096 - catalase activity [Evidence
                     IEA];
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HFS4045674.1"
                     /translation="MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAG
                     PTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDI
                     IDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVR
                     ALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDI
                     EMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFD
                     GSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADL
                     VFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDLL"
     gene            complement(24822..25712)
                     /gene="metF"
                     /locus_tag="ACHY1N_003434"
     CDS             complement(24822..25712)
                     /gene="metF"
                     /locus_tag="ACHY1N_003434"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HFS4045675.1"
                     /translation="MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTI
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAICHTLGVRPGL"
     gene            25788..25922
                     /locus_tag="ACHY1N_003435"
     CDS             25788..25922
                     /locus_tag="ACHY1N_003435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045676.1"
                     /translation="MKEKPKGVNRKMTNDGEEKSGKMKKLQDGKKKKIRYAKQTGLQI
                     "
     gene            complement(26061..28493)
                     /gene="metL"
                     /locus_tag="ACHY1N_003436"
     CDS             complement(26061..28493)
                     /gene="metL"
                     /locus_tag="ACHY1N_003436"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HFS4045677.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLINWLKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADSLISAF
                     VSDLERLAALLDSGINDAVYAEVVGHGEVWSARLMSAVLNQQGLPAAWLDAREFLRAE
                     RAAQPQVDEGLSYPLLQQLLVQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPV
                     SGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDVCLIEFQVPASQDFKLAH
                     KEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADSALKILDEAGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLSYD
                     GLDASRALAFFNDEAVEQDEESLFLWMRAHPYDDLVVLDVTASQQLADQYLDFASHGF
                     HVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDVMRKLVILAR
                     EAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNEQMVQRLEAAREMGLVLRYVA
                     RFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            complement(28496..29656)
                     /gene="metB"
                     /locus_tag="ACHY1N_003437"
     CDS             complement(28496..29656)
                     /gene="metB"
                     /locus_tag="ACHY1N_003437"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFS4045678.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLAKRGCYRVLFVDQGDEQALRAALADKPKLVLVESPSNPLLRVVDIAKIC
                     HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDV
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPENQGHEIAARQQKGYGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            29933..30250
                     /gene="metJ"
                     /locus_tag="ACHY1N_003438"
     CDS             29933..30250
                     /gene="metJ"
                     /locus_tag="ACHY1N_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HFS4045679.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPET
                     WEY"
     gene            30434..31042
                     /gene="yiiX"
                     /locus_tag="ACHY1N_003439"
     CDS             30434..31042
                     /gene="yiiX"
                     /locus_tag="ACHY1N_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX family permuted papain-like enzyme"
                     /protein_id="HFS4045680.1"
                     /translation="MKNRLLILSLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATH
                     SDYSHTGMLVIRNKKPYVFEAVGPVKYTPLKQWIAHGEKGKYVVRRVEGGLSVEQQQK
                     LAQTAKRYLGKPYDFSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSNPLV
                     QAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW"
     gene            31187..31862
                     /locus_tag="ACHY1N_003440"
                     /pseudo
     CDS             31187..31862
                     /locus_tag="ACHY1N_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT         7764 a         8880 c         8092 g         7257 t
ORIGIN      
        1 aaccgtgatc acattaaaaa caaaaatttc caccgaggag aaaaaatacc ctcaaaaacc
       61 acctgaataa ttaaccatta tcgttaaaac aacacgttaa ataatcacat aacaaactcc
      121 attaatcatt aaaaatgggc acagcaatag aaaataatta tattcaatta attaaaatat
      181 gtattggttg atgtatttga aaatatgatt ttcatgggga gtgtgaaggt aaagaagaca
      241 caatgataaa aaggaatgtg acaaataatg gttctggttg ggcgttaaat ttaagctcac
      301 cagaatgctg acaaatttct gcctgatgtg gcgtaaacgc cttatccgcc tacgaagtgt
      361 cgcactttgt aggcgtggta agctccccat tttcagggga gcaatataaa caaattactc
      421 taaccgcgcc tgcgcaaaag caattgcctg cgccacctgc tgcggtgaga cgccgccttt
      481 tgccgcacgc ttgtcgaggc acgattgcag cgacagaatc ggatagacat cttcgtcaat
      541 caccgggctg aatttctgca actcgtcgag cggcagatct tccagcggtt tgccctgacg
      601 aatggcttcc accaccgctt caccaacaat atggtgcgcc tcgcggaacg gtacgccttt
      661 cgccaccaga taatccgcca gttcggtggc gttggcgtaa ccctgctgag ccgcttcctg
      721 gcaacgtgga cgtttcacct gaatgccgtc cagcaccagc gccgccatat gcaggcagtc
      781 cagccaggta tcgagcgcgt cgaacagacc ttctttgtct tcctgcatat ctttgttgta
      841 agccagcggc aaacctttca gcgtcatcat catgccggtt aacgccccct gcacccgacc
      901 gcatttaccg cgaatcagct ccagcgcatc cgggtttttc ttctgcggca ttaatgatga
      961 accggaagtc acgcggtcag aaagctccac aaaccccgct tcgccggtgt taaagaaaat
     1021 cagatcttca gcaaaacgcg acagatgcac catgccgata gcggcagcag aaagcagttc
     1081 caacacatgg tcacggtcag aaacgctgtc gagactgtta cgggtcgccg aagcaaagcc
     1141 cagccagcct gctaactgtt cacggtcgat ttcataggcc gttcccgcca gcgcgccaca
     1201 gcctagcggg ctgacatcca gacgcttaag cgcatcctgc aaacggcttt catcacgcgc
     1261 cagcatctca acataggcca ggcaccagtg cgcgaacgtc accggctggg cgcgttgcag
     1321 gtgagtgtaa cctggcatta ccgcgtcctg attgttttgt gcggtttcca ccagcgccga
     1381 ttgcagctgc cggttagccg tcagtaactc gctaacggta tctttgcacc acagtttcag
     1441 gtcagtcgct acctgatcat tacggctacg cccggtatgc agctttttgc ctaactggcc
     1501 cactttgtcg atcagtttgc cttccaccca gctatggata tcttcggcgt cgctttcaag
     1561 gatttgttgt ggcctggcgc gaacatcttc cagcaacacg ttcagcgcct cttccagttg
     1621 cgcctgctct tctgcggtta acacgcctac cgtgaccagg gctttggacc aggccacaga
     1681 gccaacaata tcctgctccg ccagacggta atcaaagcgc agtgagtcgt tgaattgttt
     1741 gaaccgttga tctgctgcct gggtaaaacg cccgccccaa agtgccataa ctctgtttcc
     1801 ttattttgaa attcaatgcc ggaaagctgc gcctccggcc aacaaaactt aagctaaaat
     1861 ccgcgtaccc atcggcatac cgttaaacag tgccggaagc tgctccgcat gacgccagga
     1921 ggcgatatct accggacggc ccagcgtgcg ggccgcatcc agcgccgcgt tcactttcac
     1981 tatcatgccg tcagtaataa tgccctgctc aatcagttgt tctgctttcg cggcggtcat
     2041 ttcggcaatg cgttgccctt tgccgtcgag aatgccgctg acgtcggaga gcaaaatcag
     2101 atccgcgccc agcgttgccg ccagcgccgt tgccgcctgg tcggcattga cgttcatcag
     2161 ttgcccttcg tctgttacgc caatggagct gaccaccggc agataaccgt tctccagcaa
     2221 ggagttgata agcttaggcg aacctggctg cgccagtcca acatgaccta actcttcatc
     2281 aagctgggtc actttgacgc tgtcgccgtc accgagaaac aaacctacgg ccgcaatctg
     2341 atgtttcttc gcccatgcca acagggtttt atttgccgtt cccgccagtg ctccggtgat
     2401 aatgtctatc tgatcagcag gcgtcacccg caggccgttt ttctttttca ccggcagatt
     2461 cagccctttc atcagctcat ccaccacgca accgccgccg tgcacaatca ccagcggacg
     2521 ctgatgtgac tcacgataat tcaccagtgc gctaaacaga cgttccagcg cctcttcact
     2581 atccagcagt acgccgccca gtttgataat taatggattc atcattgcac ccttaaataa
     2641 gagactgcgt ttccgcatag ccgaaacgaa tattggcgca ctgtaccgct tgtgccgccg
     2701 cgcctttcag taagttgtct tcggtcgcca caataatcag atgctcgccc tgaacggcaa
     2761 acccgatatc gcaaaatggc agcccaacga catttttcag cgccggaacg cctttgtcat
     2821 acagccgcac cagcggttta tgggcatacg cctgctgtaa cacttgcgcg acttgcgcct
     2881 gggtcacacc cgatttcagg cggcaggtaa tggtttcgag aatgccgcgc gggaaattgc
     2941 ccagatgtgg ggtgaagata acgtcagcac cgaggtgtgt ggcgatctct ggttgatggc
     3001 gatgagtaaa gacgccatac ggttgcaggc taacttcaca aaagctgttt gaaatggccg
     3061 ctttacgccc tgcaccgctc acgccgctgg tggcgttgat caccggccac tgattgaggt
     3121 caagaagatc ggcatcaatc aacggtttca gcgccagctg tgccgccgtc ggataacagc
     3181 ccggcaccgc aatcaaattc gcttctttta atttattacc gcaccactcc gccagaccgt
     3241 aggctgcctg ttccaacagt tccgggtatt gatgggtaaa gccgtaatat ttttcataga
     3301 aggtggcgtc gttaacacga aacgcgccgg aaaggtcgaa caccacgcag cccgcttcaa
     3361 gaaactgcgg cgctaaatcg tggctaactt catgggcggt ggcgagaaac actacgtcca
     3421 cccctgggct aaactcgctg atatccgaca tcggctgcaa cggcagatca acgatgcctt
     3481 ttagctgcgg atgcaaatcg gagattaact tgcccgcatc attgctttgc gctgaaacag
     3541 tcaaagcggt tatgttcata tgcggatggc gatttacata ggtcactagc tctgcgccag
     3601 cgtagccgct ggcacccaca atcagcgtat tcaacatcgg ggctattcac cttcttatgt
     3661 ctggttgcca ggttaaacgt aaaacattca ccttacggct ggtgggtttt attacgctca
     3721 acgttagtgt atttttattc ataaatactg catgaatatt gatactatca tgaccagagg
     3781 tgtgtcaaca atgaaaaaca aattaccgcc atttatcgag atttaccgtg ctctgattgc
     3841 cacaccttca ataagcgcca cggaagaggc actcgatcaa agcaatgcag atttaatcac
     3901 tctgctggcg gactggttta aagatttagg cttcaatgtg gaagtgcagc ctgtgccagg
     3961 aactcgcaac aaatttaata tgctggcaag tatcggacag ggggctggcg gcttgttgct
     4021 ggcggggcat accgatacgg taccatttga tgacggtcgc tggacgcgtg atccgtttac
     4081 actgacggag catgacggca agctttacgg cttaggcacc gccgacatga aaggcttttt
     4141 tgcgtttatc cttgatgcgc tacgcgatgt cgacgtcacg aaactgaaaa aaccgctcta
     4201 cattctggcg actgctgatg aagaaaccag tatggccgga gcgcgttatt ttgccgaaac
     4261 taccgccctg cgcccggatt gcgccatcat tggcgaaccg acgtcactac aaccggtacg
     4321 cgcacataaa ggtcatatct ctaacgccat ccgtattcag ggccagtcgg ggcactccag
     4381 cgatccagca cgcggagtta acgctatcga actaatgcac gacgccatcg ggcatatttt
     4441 gcaattgcgc gataacctga aagaacgtta tcactacgaa gcgtttaccg tgccataccc
     4501 tacgctcaac ctcgggcata ttcacggtgg cgacgcttct aaccgtattt gcgcttgctg
     4561 tgagttgcat atggatattc gtccgctgcc tggcatgaca ctcaatgaac ttaatggttt
     4621 gctcaacgat gcattggctc cggtgagcga acgctggccg ggtcgtctga cggtcgacga
     4681 gctgcatccg ccgatccctg gctatgaatg cccaccgaat catcaactgg ttgaagtagt
     4741 tgagaaattg ctcggagcaa agaccgaagt ggtgaactac tgtaccgaag cgccgtttat
     4801 tcaaacgtta tgcccgacgc tggtgttggg gcctggctca attaatcagg ctcatcaacc
     4861 tgatgaatat ctggaaacac ggtttatcaa gcccacccgc gaactgataa cccaggtaat
     4921 tcaccatttt tgctggcatt aaaacgtagg ccggataagg cgctcgcgcc gcatccggca
     4981 ctgttgtcaa actccagtgc cgcaataatg tcggatgcga tacttgcgca tcttatccga
     5041 cctacacctt tggtgttact tggggcgatt ttttaacatt tccataagtt acgcttattt
     5101 aaagcgtcgt gaatttaatg acgtaaattc ctgctattta ttcgtttgct gaagcgattt
     5161 cgcagcattt gacgtcaccg cttttacgtg gctttataaa agacgacgaa aagcaaagcc
     5221 cgagcatatt cgcgccaatg cgacgtgaag gatacagggc tatcaaacga taagatgggg
     5281 tgtctggggt aatatgaacg aacaatattc cgcattgcgt agtaatgtca gtatgctcgg
     5341 caaagtgctg ggagaaacca tcaaggatgc gttgggagaa cacattcttg aacgcgtaga
     5401 aactatccgt aagttgtcca aatcttcacg cgctggcaat gatgctaacc gccaggagtt
     5461 actcaccacc ttacaaaatt tgtcgaacga cgagctgctg cccgttgcgc gtgcgtttag
     5521 tcagttcctg aacctggcca acaccgccga gcaataccac agcatttcgc cgaaaggcga
     5581 agctgccagc aacccggaag tgatcgcccg caccctgcgt aaactgaaaa accagccgga
     5641 actgagcgaa gacaccatca aaaaagcagt ggaatcgctg tcgctggaac tggtcctcac
     5701 ggctcaccct accgaaatta cccgtcgtac actgatccac aaaatggtgg aagtgaacgc
     5761 ctgcttaaaa cagctcgata acaaagatat cgctgactac gaacacaacc agctgatgcg
     5821 tcgcctgcgc cagttaatcg cccagtcatg gcataccgat gaaatccgta agctgcgtcc
     5881 aagcccggta gatgaagcca aatggggctt tgccgtagtg gaaaacagcc tgtggcaagg
     5941 cgtaccaaat tacctgcgcg aactgaacga acaactggaa gagaacctcg gctacaaact
     6001 gcccgtcgaa tttgttccgg tccgttttac ttcgtggatg ggcggcgacc gcgacggcaa
     6061 cccgaacgtc actgccgata tcacccgcca cgtcctgcta ctcagccgct ggaaagccac
     6121 cgatttgttc ctgaaagata ttcaggtgct ggtttctgaa ctgtcgatgg ttgaagcgac
     6181 ccctgaactg ctggcgctgg ttggcgaaga aggtgccgca gaaccgtatc gctatctgat
     6241 gaaaaacctg cgttctcgcc tgatggcgac acaggcatgg ctggaagcgc gcctgaaagg
     6301 cgaagaactg ccaaaaccag aagggctgct gacacaaaac gaagaactgt gggaaccgct
     6361 ctacgcttgc taccagtcac ttcaggcgtg tggcatgggt attatcgcca acggcgatct
     6421 gctcgacacc ctgcgccgcg tgaaatgttt cggcgtaccg ctggtccgta ttgatatccg
     6481 tcaggagagc acccgccata ccgaagcgct gggcgagctg acccgctacc tcggtatcgg
     6541 cgactacgaa agctggtcag aggccgacaa acaggcgttc ctgatccgcg aactgaactc
     6601 caaacgtccg cttctgccgc gcaactggca accaagcgcc gaaacgcgcg aagtgctcga
     6661 tacctgccag gtgattgccg aagcgccgca aggctccatt gccgcctacg tgatctcgat
     6721 ggcgaaaacg ccgtccgacg tactggctgt ccacctgctg ctgaaagaag cgggtatcgg
     6781 gtttgcgatg ccggttgctc cgctgtttga aaccctcgat gatctgaaca acgccaacga
     6841 tgtcatgacc cagctgctca atattgactg gtatcgtggc ctgattcagg gcaaacagat
     6901 ggtgatgatt ggctattccg actcagcaaa agatgcggga gtgatggcag cttcctgggc
     6961 gcaatatcag gcacaggatg cattaatcaa aacctgcgaa aaagcgggta ttgagctgac
     7021 gttgttccac ggtcgcggcg gttccattgg tcgcggcggc gcacctgctc atgcggcgct
     7081 gctgtcacaa ccgccaggaa gcctgaaagg tggcctgcgc gtgactgaac agggcgagat
     7141 gatccgcttt aaatatggtc tgccagaaat caccgtcagc agcctgtcgc tgtacaccgg
     7201 ggcgattctg gaagccaacc tgctgccacc acctgagccg aaagagagct ggcgtcgcat
     7261 tatggatgaa ctgtcagtca tctcctgcga tctctaccgt ggctacgtac gtgaaaacaa
     7321 agattttgtg ccttacttcc gctccgctac gccggaacaa gaattgggca aactgccgtt
     7381 gggttcacgt ccggcgaaac gtcgcccaac cggcggcgtc gagtcgctgc gcgccatacc
     7441 gtggattttt gcctggacgc aaaaccgcct gatgctcccc gcctggctgg gtgcaggtac
     7501 ggcgctgcaa aaagtggtcg aagatggcaa acagagcgag ctggaagcca tgtgccgcga
     7561 ttggccattc ttctcgacgc gtctcggcat gctggagatg gtcttcgcca aagcagacct
     7621 gtggctggcg gaatactatg accaacgcct ggtagacaaa gcactgtggc cgttaggtaa
     7681 agagttacgc aacctgcaag aagaagacat caaagtggtg ctggcgattg ccaacgattc
     7741 ccatctaatg gccgatctgc cgtggattgc agagtctatt cagctacgga atatttacac
     7801 cgacccgctg aacgtattgc aggccgagtt actgcaccgc tcccgccagg cagaaaaaga
     7861 aggccaggaa ccggatcctc gcgtcgaaca agcgttaatg gtcactattg ccgggattgc
     7921 ggcaggtatg cgtaataccg gctaatcttc ctcttctgca aaccctcgtg cttttgcgcg
     7981 agggttttat gaaatacttc tgttctaaca ccctcgtttt caatatattt ctgtctgcat
     8041 tttattcaaa ttctgaatat accttcagat atccttaagg aattgtcgtt acattcggcg
     8101 atattttttt caagacaggt tcttactatg cattccacag aagtccaggc taaacccctt
     8161 tttagctgga aagccctggg ttgggcactg ctctactttt ggtttttctc tactctgcta
     8221 caggccatta tttacatcag tggttatagt ggcaccaacg gcattcgcga ctcgctgtta
     8281 ttcagctcgc tgtggttgat cccggtattc ctctttccga agcggattaa aattattgcc
     8341 gcagtaatcg gcgtggtgct atgggcggcc tctctggcgg cgctatgcta ctacgtcatc
     8401 tacgggcagg agttctcgca gagcgttctg tttgtgatgt tcgaaaccaa caccaacgaa
     8461 gccagcgagt atttaagcca gtatttcagc ctgaaaattg tgcttatcgc gctggcctat
     8521 acggcggtgg cagttctgct gtggacacgc ctgcgcccgg tctatattcc aaagccgtgg
     8581 cgttatgttg tctcttttgc cctgctttat ggcttgattc tgcatccgat cgccatgaat
     8641 acgtttatca aaaacaagcc gtttgagaaa acgttggata acctggcctc gcgtatggag
     8701 cctgccgcac cgtggcaatt cctgaccggc tattatcagt atcgtcagca actaaactcg
     8761 ctaacaaagt tactgaatga aaataatgcc ttgccgccac tggctaattt caaagatgaa
     8821 tcgggtaacg aaccgcgcac tttagtgctg gtgattggcg agtcgaccca gcgcggacgc
     8881 atgagtctgt acggttatcc gcgtgaaacc acgccggagc tggatgcgct gcataaaacc
     8941 gatccgaatc tgaccgtgtt taataacgta gttacgtctc gtccgtacac cattgaaatc
     9001 ctgcaacagg cgctgacctt tgccaatgaa aagaacccgg atctgtatct gacgcagccg
     9061 tcgctgatga acatgatgaa acaggcaggt tataaaacct tctggatcac caaccagcag
     9121 acgatgaccg cccgcaatac catgctgacg gtattttcga agcagaccga caaacagttc
     9181 tatatgaacc agcaacgtac gcagagtgcg cgtgaatacg acaccaacgt gctgaaacca
     9241 ttccaggaag tgctgaagga cccggcgccg aagaaactga tcatcgttca tctgctgggt
     9301 acgcatatca aatacaaata ccgctacccg gaaaatcagg gcaagtttga tggcaatacc
     9361 gatcatgttc cgcctggatt aaacgcggaa gagctggagt catataacga ttatgacaac
     9421 gctaacctgt ataacgatca tgtggttgcc agcctgatta aagactttaa agcagcaaac
     9481 ccgaacggtt tcctggttta tttctctgac cacggtgaag aggtttacga cacgccgccg
     9541 cacaaaactc aggggcgtaa cgaagacaac ccgacgcgcc acatgtacac cattccgttc
     9601 ctgctgtgga cgtcggaaaa atggcaagcg actcatccgc gtgatttctc gcaggatgtt
     9661 gatcgtaaat acagcctggc ggaactgatc cacacctggt cagatttagc aggcttatct
     9721 tacgacggtt acgatccaac ccgttcagtg gtgaatccgc agttcaaaga aactacccgc
     9781 tggattggta acccgtacaa gaaaaacgcg ctgatcgatt acgacacgct gccgtatggc
     9841 gatcaggtgg gtaatcagta aatgaccttt gtatcgcgtc tggcgctatt tgccggatgc
     9901 gatactgccg caatgtttac atcgaactcc cctcaggcca cacttttcag gtggcctttt
     9961 ttaataatgc cagttactgt tttcccgtct acatacctaa gggaataaca tgtatcacga
    10021 cgtcagctat ctgctctccc gcctgatcaa cggcccgctg tccctgcgcc agatttactt
    10081 tgccagcagt aacggtccgg cgcccgatct tgcgtatcag gtcgattttc cacggctgga
    10141 aatagtgctg gaaggtgagt ttgttgatac cggcgctgga gcaacgttag ttcccggcga
    10201 tgtgctgtac gttcccgctg gtggctggaa ttttccacaa tggcaagccc ccgctactac
    10261 ctttagcgtg ctgtttggca aacagcaact cggcttcagc gtcgtgcaat gggatggcaa
    10321 acagtatcaa aatctggcga agcaacacgt cgcccgacgc ggcccgcgca ttggttcttt
    10381 tctgctacaa acgctcaatg aaatgcaaat gcagccacag gagcagcaaa cggcaaggct
    10441 tatcgtcgcc agcctgctta gccactgccg cgatttgctc ggcagccaaa tacagaccgc
    10501 ctcacgcagc caggctctat tcgaagctat tcgtgattat atcgacgaac gctatgcctc
    10561 cgcgcttacc cgcgaatctg tcgcacaggc gttctatatt tcaccaaact atctctcgca
    10621 cctgtttcaa aagacggggg ccattggttt taacgaatac ctgaatcaca cgcgactgga
    10681 gcacgctaag acgttattga aaggctatga cctgaaggta aaagaagtgg cgcacgcctg
    10741 cggctttgtc gacagcaact acttctgccg tctgtttcgt aaaaacaccg aacgctcgcc
    10801 gtcggaatat cgtcggcagt accacagcca actgacagaa aaaccgacta ctccagaata
    10861 agatgggttt gctgcggcgc agaaagcact ttacgtaccg cgctcatcac ccgctgcggc
    10921 tcacgcagga acgcgtagat actgcattgc acgtagcgac aatgttcaaa tcgctcggca
    10981 ccagcaagct cgatatccgt aatcaacagc gcaacatccg cccggcggat atcctcgtcc
    11041 gctaaacgat tctccgttcc cagcgcgccc tgagtttcaa tgctgacgcc ccacttctct
    11101 aactggcaca acttttccag ccgttccgcc gccatataag tatgcgccac gccactgacg
    11161 caggcggtta ctgccaccag gtatgccatt ttaacctccc acggtaacct gaaatccggc
    11221 ccgttctgcc atttcgcgca tcgttgccac atcggctgac gacggcgcag aaacctcttt
    11281 catcgaccat gttttcccca gcagacggta tttcggttcg ccgtactgat gaaacggtaa
    11341 cagatggatc tgcctgatat tcagcgggat cagcacgtcc agcgcctgct gcatattctc
    11401 ccggctgagt gtgaaaccgg ggatcagcgg caaacgcggg atcacgttga caccttcact
    11461 caccagcaaa cgcagattct ccagcacgcg tggcaggttc atcttcacca catcccgcgc
    11521 ctgagtcgcg tccataattt ttaaatcgaa caacacttca tcgcacaatt tcgccagcgg
    11581 taacagcttg ctggctggcg cgtctccggc agtttcgatg gcgcatgaca cgccccacag
    11641 ccgcagtcgc tgtaaaaaac gggtagcaaa ctcggcctgc attaacactt cgccgccaga
    11701 aagcgtgacg ccgccgccgg acgtgcgaaa gaaaatgtca tctttcatca cttcccgttc
    11761 cagagcgtca aggctgatat cgcgaccaat ccgttcaaac gcaccggagg ggcattcatc
    11821 cgcatcacgc aaacatttcg cacagtgcag acatttcgcc tctctgcgta ccgtctggat
    11881 tttgccggag atcgactccg gattagcaca ccacgggcaa agatgcggac agcctttaaa
    11941 aaagaccacc gtacgaatgc cctcgccgtc attcagtgaa taacgctgaa tgttgaaaat
    12001 gcgcgccaca tcatcgcggc gcgtttccac aacgttacag ctgatgcgct gtccggcgga
    12061 tgatgtcatc ctggatctcc ttcgacagtt cgacaaagaa ggcgctgtat ccggcaacgc
    12121 gcaccaccag cccggcataa tcttgtgggc gctgttgcgc ttcccgcaac gtgtcggcgt
    12181 tcaccacgtt aaactgaata tgctgcaact taagctgggt aaacgcccgt aagaagtcgg
    12241 ccagtttgcg taatcccgct tcaccttcca gggtcgccgg agtgaatttc acgttcagca
    12301 acgtaccgtt agacagcagc gtgttatcga gcttactgac tgacttcagt accgctgttg
    12361 gcccttgtgc gtcctggccc agcataggtg acaagccgcc gtctgccagt tgttccccgg
    12421 caaaacgacc gtctggcgtc gcgccaacca ccgatcccaa cgggacgtga gcagaaacgg
    12481 tatacgatcc cggcgtgaag taaccgccgc gcgggttctg gtatttttcc acttctttgc
    12541 agtagtggcg taacagttcg gcgctgatgt tatccacctc gtcgatatcg ttaccgtatt
    12601 tctcgaagcg gttaattaag cgagcacgga ctttttcgcc ttctggcgtt gcaaagttgg
    12661 cttttaatac cgacagcaat tcgtcaaaac ttaaacgctg ttgctcaaaa accatccctt
    12721 tcaacgcatg gagagaatcg ctcaggttgg cgataccgat cccctgtacg ccggagaagt
    12781 tataacgcgc gccgccatcg gtaatatcgc gacctttttc cagacaatcg ctgataaaag
    12841 acgagagcag cggtacaggt gcccagtcgc gatggccgat atcacaaata ttgctgccct
    12901 caaccatcag ggtgatgtag tggctgatct tggcgcggat ctgctccagt aaaccttcat
    12961 aagtcagcgc agcattgcct tcattttcat gcaggcagat ttccatcact ttcagcagat
    13021 taaacatcgc gatgtcatgc aagccgtagg ttctgccggg aatagataat tccacacagc
    13081 ccactacgga atagtcgcgc gcatcttcca gcgaaacgcc acggttgagg aacgctggta
    13141 ccaccacttc atcgttaaag atttgcggaa taccggtgcc gaggcgaatg gtttcggcgg
    13201 ttttcatcag gaacggcgtg tcgatcaagg cgttagtgcg cacgccgagg ttcggttgcg
    13261 gtaattgcac gctttgataa gcgtcaaggc aaaggaacga aagcacgttc accgcgctac
    13321 gtccgttctc ggttaacccg ccgagcagtg cggtatagcc ggtcgggaaa cctgcgaaat
    13381 aacgcgcgct gctggtggag cgcaacagca cgatgtcgtt gcatttcacc cataaagatt
    13441 cgagtagttc tttcaggaac gccggatctt cgccctgggt taaagatgcc tgatagaacg
    13501 gcaacatata ctggtcgaag cgccccaacg atagcgaact ggcgttggat tcgtattgca
    13561 gaatgatgtt catgtaccag aataactggc acgcctgcca gaacgtctgc ggcttatgtt
    13621 cggcgttatg gcgggagatc tccgcaatag tcagcagttc ttcgcgacgc tgggcatctg
    13681 tgcagtttgc cgccattgtt tccgccagtt cagcgtaacg cagaatgtgt ttctgcgagg
    13741 cttccagcag taacagcgcg gcctgataaa agtgattctc cggctgttgc tgacaatgtt
    13801 gctgcatctg cgccaccagc tcccccagcc cgtgattcag caggcgtggg taatcaataa
    13861 taatgtgccc ctggccttta tctgtctggt tgatgctgaa aatctgcgtg ctggtcgcgg
    13921 cttttacttc atctgtcatc tgcccgttga tgaaatcttt catcgaacgt ttttcccagt
    13981 acgggaacaa ctcttcacgg tagatacgtt tatcttcttc actgatagca aagcggtcct
    14041 gcggacgcgt cgggaattga tccagctctt tcagcagcca gtaagggtcc atttccggcg
    14101 acataatccc agcgcgcggt tttacggtgc ggttaccggc aatcagttct tcatcacgaa
    14161 tcgaaatttc aacatgttca aggatatacg ctgttgcttt cgcccggcgc aatatcaccg
    14221 gttcgccttc ggtttgccga tggctggcgg tataaagcag cgcccgctcc agcgagattt
    14281 cacgggtatt ggcaaacagt gcagttttga ggcgagagat acgattcgtc atgaggaact
    14341 cctgtgggaa agcgaacccg cccttgcgag cgggagaaga acttaagcgg tttgcgccag
    14401 gtgagcttca attttgctca taatggcgtc agcacgtttt actgcatcgc tgatgttgac
    14461 gcgcacgatg gtcttgccag caaaacgctc ttcaaacttg atgccgatat ctttggtcag
    14521 aatcaccata tcagcgctcg ccacatcttc cgcagtcagt tcattttcca gaccaattga
    14581 cccctgggtt tctactttca cttcccagcc tttcgctttc gcggcacttt ccagcgcctc
    14641 tgctgccata taggtatggg caacacctga aggacatgcg gttactgcaa taattttcgt
    14701 catggctcgt tcctcaatta attaatttca aaatccaaat ccaggtcgtc ttctttttca
    14761 tcagtcgaag acccattttt acgcgccaga cttttcagca cgttcacaca aacagccgtc
    14821 accactgctc cgacagccac tgctgcgata taacccagct tgccttcaac caccggcagc
    14881 acaatcagac caccccagcc tgcatagcac tgcgcaccga ccagcgccgc agttactgca
    14941 ccacaaactg aaccgaccat gatggaagga atgacacgca gcggatcggc agcggcgaaa
    15001 ggaatcgccc cttcagtaac gccaacacag cccatcacca gtgccgcttt gccggtttcg
    15061 cgctcttctg cggagaaatt tttacgacca atcagcgtcg ccagccccat ccccagcggc
    15121 gggatacaaa tacccacggc agcgatggcc accacggtat aaacaccctg agcaacgcaa
    15181 atcagcatga aggcataggc cactttgtta accggaccgc ccatatcgaa cgccagcatc
    15241 agacccatga tcaccgccag cataacaatg ctgccctgct gcatcccctg aagccactga
    15301 gtcaggctgt tggtcaacgc ccctacaggc tcgcccaagc cccacatcat gatgcctgcg
    15361 gtaatcagtg tgccgacgat aggaataatg aagataggca tcaccgagcg cagaacttta
    15421 tgcaccggaa ttttcttcag gtaatgcacc acgatgccgc cgataatccc ggcgatcagt
    15481 gcaccaaaga agcccgcacc aaagctgtta ccaacccagg caccgatagc gcacggagcc
    15541 agcgcagaac gctctgcaat ggaataaccg atgtacgctg cgaggaaagg caccatcagc
    15601 gtcaagcccg caacgccgat atcaaacagt tttttcagat ttggatcggc tacggcatcc
    15661 ggcactgcgc ctttgccata caacatgacg gaaaccgcca gcaaaatacc gcccgatacc
    15721 acgaagggaa tcatgtgtga aacgcccgtc attaaatgct gacgggtatt tttcaggatc
    15781 tgcaccaact cattcataag ctgctcccgg gcttgcgaaa gcccatgtcc atatttttga
    15841 tggaggaaac aataggcaat cgcaggcgga gcaaacagtg gataaaaagg ccatttactg
    15901 gacttttgta atatcagtac aaaaatgcga tccgcctcat aacttgcgat aaaccggaag
    15961 catgccgcaa aacagcgtct tgtgagacgc gtcgcaaatt gacggttaca ttacatttgt
    16021 ccagcttttg gcagatttgt cacatggcag gccgttgccg tgcgctctta tcctgtaaac
    16081 agaaaaccgt accgggagag aggcaatggc cctgattgtg gaatttattt gtgagctacc
    16141 taacggcgta catgcacgtc cggcaagcca cgttgaaacg ctgtgtaata ctttttcatc
    16201 acaaattgag tggcataacc tgcgcactga ccgcaagggc aacgccaaaa gcgcccttgc
    16261 gctgattggc accgatacgc tggcgggcga taactgccag ttactgattt ccggggccga
    16321 cgaacaggaa gcgcaccagc gtttaagcca atggctgcgc gatgaattcc cccactgcga
    16381 tgcgccgctg gcggaagtta aatctgacga actggaacca ctgccggttt cactgaccaa
    16441 tctgaatccg caaattatcc gcgcccgcac cgtgtgcagc ggtagtgcag gcggcattct
    16501 gacgccgatc tcttctttag atctcaatgc gctgggtaat cttcccgcag ccaaaggcgt
    16561 tgacgccgag caatccgcac tggaaaacgg cctgacgctg gtactgaaaa acattgagtt
    16621 tcgtctgctg gatagcgacg gtgccaccag cgcgattctg gaagcgcacc gatccctggc
    16681 tggcgatact tccctgcgcg aacatttact ggcaggcgtc agcgccggat taagctgcgc
    16741 cgaagcgatt gtcaccagtg cgaatcactt ttgcgaagag ttcgcccgtt ccagcagcag
    16801 ctacctgcaa gaacgtgccc tggacgtacg cgacgtctgc ttccagttac tccagcaaat
    16861 ctacggtgag caacgcttcc cggcaccggg caaactgacg cagcccgcca tttgtatggc
    16921 tgatgaactg actcccagcc agttcctcga actggataaa aatcacctca aaggtctgtt
    16981 actgaaaagt ggcggcacca cctcacatac cgtaattctt gcccgttcgt tcaacattcc
    17041 gacactggtt ggtgtagata ttgatgccct tactccgtgg cagcatcaaa cgatttatat
    17101 cgacggcaac gctggggcga ttgtggttga gccaggagaa gccgtagctc gttattatca
    17161 gcaagaagcc cgcgtacagg acgccctgcg tgagcaacag cgtgtctggc tgacccaaca
    17221 agcccgtacc gctgacggta tccgcattga aattgccgct aacatcgctc actccgtgga
    17281 agcgcaggcc gcattcggca atggtgcgga aggcgttggt ttgttccgca ctgaaatgct
    17341 ctatatggat cgcaccagtg caccgggcga aagcgagctg tacaacattt tttgtcaggc
    17401 gctggagtct gccaacggac gcagcattat tgtgcgcact atggacattg gcggcgacaa
    17461 acccgttgat tatctgaaca ttccggcaga agctaacccg ttcctcggtt atcgcgctgt
    17521 gcgtatttat gaagaatacg cctcgctgtt caccacacaa ctacggtcga tcctgcgcgc
    17581 ctccgctcac ggcagcctga aaatcatgat cccgatgatc tcctcaatgg aagagatctt
    17641 atgggtgaaa gaaaaactgg cggaagccaa acagcaactg cgtaacgaac acattccgtt
    17701 tgatgagaag atccagcttg gcattatgct ggaagtaccg tcggtgatgt tcatcatcga
    17761 tcaatgctgc gaagagattg atttctttag tattggtagt aatgacctga cgcaatatct
    17821 gctggcagtg gatcgcgata acgctaaggt tactcgtcac tacaacagcc tgaatccggc
    17881 attcttgcgg gcgctcgatt acgccgtgca ggcggtgcat cgccagggca aatggattgg
    17941 tctgtgcggt gagctgggag cgaaaggttc cgtgctgccg ttgctggtcg gcttagggct
    18001 ggatgaactc agcatgagcg caccatcaat tccggcggcg aaagcgcgga tggcgcaact
    18061 tgatagccgt gagtgccgca agttgctcaa ccaggcaatg gcctgccgta cttcgctgga
    18121 agtggaacac ctgctggcgc aattccgcat gacccaacag gacgcaccgc tggtcaccgc
    18181 cgagtgcatc acgctggaaa gtgactggcg cagcaaagaa gaagtgctca aaggcatgac
    18241 cgataacctg ctgctggcgg gccgctgccg ctatccgcgt aaactggaag ccgacttatg
    18301 ggcgcgcgag gccgttttct ctaccggtct gggctttagt tttgccattc cacacagcaa
    18361 atcagaacac attgagcaat ccaccatcag cgtggcgcgt ctgcaagcgc cggtgcgctg
    18421 gggcgatgat gaagcgcaat tcatcattat gttaaccctg aacaaacacg ctgcgggcga
    18481 tcagcacatg cgcattttct cgcgcctcgc tcgccgcatc atgcacgaag aattccgtaa
    18541 cgcgctggtt aacgccgcct ctgccgacgc tatcgccagc ctgctgcaac atgaactgga
    18601 actgtaaaag gaaacatcat ggaactgtat ctggacaccg ctaacgtcgc agaagtcgaa
    18661 cgtctggcac gcatattccc cattgccggg gtgacaacta acccgagcat tatcgctgcc
    18721 agcaaggagt ccatatggga agttctgccg cgtctgcaaa aagcgattgg tgatgagggc
    18781 attctgtttg ctcagactat gagtcgtgac gcgcagggta tagtggaaga agcgaagcgc
    18841 ctgcgcgacg ccattccggg cattgtggtg aaaatcccgg tgacttccga aggtctggcc
    18901 gccattaaga tgctgaaaaa agagggtatt actacgcttg gcaccgcagt gtacagtgct
    18961 gcacaagggt tactggccgc gctggcaggg gcaaaatacg ttgctccgta tgttaaccgc
    19021 gtagatgccc agggcgggga cggcattcgt acggttcagg agctgcaagc gctgttagaa
    19081 atgcacgcac cagaaagcat ggtgctggcg gccagcttta aaacgccgcg tcaggcgctg
    19141 gactgtttac tggcaggatg tgaatccatc accctgccct tagatgtagc gcaacaaatg
    19201 ctcaacaccc ctgcggtaga gtcagctata gagaagttcg aacacgactg gaatgccgca
    19261 tttggcacta ctcatctcta aaggagcaat tatggaccgc attattcaat caccgggtaa
    19321 atacatccag ggcgctgatg tgattaatcg tctgggcgaa tacctgaagc cgctggcaga
    19381 acgctggtta gtggtgggtg acaaatttgt tttaggtttt gctcaatcca ctgtcgagaa
    19441 aagctttaaa gatgctggac tggtagtaga aattgcgccg tttggcggtg aatgttcgca
    19501 aaatgagatc gaccgtctgc gtggcatcgc ggagactgcg cagtgtggcg caattctcgg
    19561 tatcggtggc ggaaaaaccc tcgatactgc caaagcactg gcacatttca tgggtgttcc
    19621 ggtagcgatc gcaccgacta tcgcctctac cgatgcaccg tgcagcgcat tgtctgttat
    19681 ctacaccgat gagggtgagt ttgaccgcta tctgctgttg ccaaataacc cgaatatggt
    19741 cattgtcgac accaaaatcg tcgcgggcgc acctgcacgt ctgttagcag cgggtatcgg
    19801 cgatgcgctg gcaacctggt ttgaagcgcg tgcttgctct cgtagcggcg cgaccaccat
    19861 ggcgggcggc aagtgcaccc aggcggcgct ggcactggct gaactgtgct acaacaccct
    19921 gctggaagaa ggcgaaaaag cgatgcttgc cgccgaacag catgtagtaa ccccggcgct
    19981 ggagcgcgtg attgaagcga acacctattt gagcggcgtt ggttttgaaa gcggcgggct
    20041 ggcggcggct cacgcggtgc ataacggcct gaccgctatc ccggacgcgc atcactatta
    20101 tcacggtgaa aaagtggcat ttggtacgct gacgcagctg gttctggaaa acgcaccggt
    20161 tgaggaaatc gaaaccgtag ctgcacttag ccatgcggta ggtttgccaa taactctcgc
    20221 tcaactggat attaaagaag atgtcccggc gaaaatgcga attgtggcag aagcggcatg
    20281 tgcagaaggt gaaaccattc acaacatgcc tggcggcgcg acgccagatc aggtttacgc
    20341 cgctctgctg gtagccgacc agtacggtca gcgtttcctg caagagtggg aataacctac
    20401 tccaaactcc cggcttgtcc gggagtttga acgcaaaatt gcctgatgcg ctacgtttat
    20461 caagcctacg aaatctctgc aatatattga atatgcgtgc ttttgtaggc cggataaggc
    20521 gttcactccg catccggcac tctgtgccag taatctgaaa ctcccacgtt gttcaggagt
    20581 tttttatccg cttctggaca ttttctccac agaacaatcg ttagcccgga aggtcgaatc
    20641 tgtgactctt attttcacgg acgaaccaga tgaaagcttc actggcgctg ctcagcctgc
    20701 taacggcatt taccagccac tccttaaaat ctcccgccgt tccaccaacc gtggtacaaa
    20761 tccaggccaa taccaacctt gccatcgcag acggtgccag acagcaaatc ggcagcacgc
    20821 tattttacga tccggcgtat atgcagctta cctatcctgg cggtgatgtc ccgcaagaac
    20881 gcggggtatg ttccgatgtg gtgatccgtg cattgcgcag ccagaaggtc gatttgcaga
    20941 aactggtgca cgaagatatg gcgaagaatt ttgccgagta cccgcaaaaa tggcagttaa
    21001 agcgcccgga cagcaacatc gatcaccgtc gggtgcctaa tctggaaacc tggtttaccc
    21061 gccacgataa aacacgcccc atcagcaaga accccagtga ctatcaagcg ggcgatattg
    21121 tctcctggcg actggataac ggactggcac atattggggt ggtgtcagat ggcttcgccc
    21181 gcgacggtac gccgctggtg atacataaca ttggcgcagg cgcgcaggaa gaagatgtgc
    21241 tgtttagctg gcggatggtg gggcattatc gttattttgt taaataagcg atcgccccac
    21301 atgaagaaaa aattcagatg ctttttacac tgacagcttc ttttttctta cggctcacca
    21361 gcgccagtgc cagcacaatc agcacaatac cgctaccttc aacggccccc ggattctcac
    21421 cgagcagcca ccaggaaaag agtacgccgc aaacgggaac ggccagcgtg cttaagctgg
    21481 caatactggc aggcaagttt ttcaatacaa acaaccataa gctccacgcc agcgccgtcg
    21541 ccagaatcgc actgtaggcc agcgcccaga acacggtggg ctgccagtca atttcacgtt
    21601 gcggcaccag taaagcgacc acactcatca ccagcgccgc atagagcatc tgccaggatg
    21661 ttaacgataa taaatccacg cgcggatgac gggtgtatag gcgtttagca acaatcgcgc
    21721 tcgcccccca actgacgccg gagaggattg ccagcatggc acttttcatt gaagagaaat
    21781 cgagttgcca cggctgcaac accaaaaata agccgaaagc ggcaatcagt atcgcgaaat
    21841 attgcccacg tcgcaggcgt tcaccgagaa acaacgcggc gaaaatcacc acccagaacg
    21901 gcatggtata gcttaggatc gccaccttcc ccgctccgcc gctgaccagc gcccactgcg
    21961 ccaggccaac catcccgcag gtttgtaaca gggcaatggc taaggtgtat ttaaacggtg
    22021 tcgggcgcat tccgcgacca cgtaataaaa ggacgatgaa taaaacgaga gcgccgaaaa
    22081 tgcagcgtaa ggcggtaaag tcgaaggcac cgatgtagct ggtgacttgc ttcatgaaaa
    22141 tccagctata actccagata agtgtgagca caaccaggcc actgattgcc agtgggttgc
    22201 tctttcctgc ggcagacatg agagatccag tgtgtagttt tcctgtggac actatacgcc
    22261 ggtaaagaaa cttcagcgac tgcctgaaag acagtcgctg aagaaggtca gattacagca
    22321 ggtcgaaacg gtcgaggttc atcactttca cccatgccgc cacgaagtct ttaacaaact
    22381 tctcgtgggc atcgctgctg gcgtaaactt ccgctaccgc acgcaggaca gagttagaac
    22441 caaataccag atccgcacgg ctggctgtgt atttcacttc gccggtttca cggtcacgac
    22501 cttcgaacag ctctttcgat tcgtcagtcg ctttccactc gtaacgcata tccagcaagt
    22561 tcacgaagaa gtcattgctc aatacgccaa cgcggtcagt gaagacgccg tttttgctgc
    22621 catcgaagtt ggcacccagt acacgcatcc cgcccaccag cgcagtcatt tccggcgcgg
    22681 tcagcgtcag ttgctgtgct ttgtcgatca gcagtgactc ggtggtggaa acatccagac
    22741 gagcgcgata gttacggaaa ccgtcagcaa ttggctccag cagctcgaac atctcaatgt
    22801 cagtctgatc ctgacgcgca tcaacgcggc ccggcgcaaa cggtacatga atgctcaaac
    22861 ctgcggcgct tgcggctttc tcaacaccaa ccacaccagc cagcacgatg atatccgcca
    22921 gcgaggcttt accagactct ttctggattt tctccagaac aggcagagca cgaacggctg
    22981 cggcgttcac atcccagtcg cgctgcggca ttaatgccag acgcgcaccg ttggcaccac
    23041 cgcgtttgtc gccaccacgg aaggtagaag cagaagccca ggccaccgat accagctcac
    23101 taacagacag accagaatcc gcaatcgcga atttcagatc gataatgtcc tgctcggtcg
    23161 ggttgtagat cggctgcggc agcggatctt gccagatcag atcttctttc ggcacttccg
    23221 gcccgatgta gcgagatttc ggccccatat ccctgtgcgt cagtttgaac caggcacggg
    23281 caaaggcttc gttgaacgcc tgcggatcgt tgaggaaacg acgagagatc ttctcgaact
    23341 caggatcaaa acgcagcgtc aggtcggtca ccagcattgt cggtttacgt ttcttcgacg
    23401 gatcgaacgg atccgggata atttccggtg cgtctaccgc ttcgaactgg attgctccag
    23461 ccggactgcg ggtctgtacc cactcatact tgaacagatt ctcgaagaaa tagttgctcc
    23521 actgggtcgg cgtctgggtc cagactactt ccagaccaga ggtaatggca tctgcgccaa
    23581 cgccgctgcc gtaagtgctc gcccagccta aaccttgttc ttcaatcggt gcagcttctg
    23641 gatcaggacc tacgtttgat gtcggaccgg caccgtgggt tttacccagc gtatgaccac
    23701 ccgcaatcag cgccacggtt tcttcgtcgt tcatgcccat gttgccgaag gtcgcgcgga
    23761 tagctgctgc cgcagaaagc ggttcgccgc tgtgatccgg gccttccggg ttaacgtaaa
    23821 tcaggcccat ctcggttgca cccagcggtg ctttcgccag cgcttccgga tgacggtgag
    23881 tcagccaggc tttttcatca ccccagttaa catccagatc cggttcccag acgtcttcac
    23941 gaccggcacc aaaaccgaag gtacggaagc cggagttttc cagcgccacg ttacctgcga
    24001 ggataaacag gtcggcccag gagattttct gaccatattt ctgtttgatt ggccacaaca
    24061 ggcgacgcgc tttatcgagg cttacgttat ccggccagga gttcagcggt gcaaaacgtt
    24121 gctgaccacg acccgcgccg ccgcgtccat cgattgaacg gtaagtacct gcgccgtgcc
    24181 aggccatacg aataaacaga ccggcgtaac tgccccagtc ggcaggccac cacggctgag
    24241 attctgtcag cagggctttc agatcttttt tcaggccgta gtaatctaat ttgctgaatt
    24301 ctttgcggta gtcaaagtcc tcacccagtg ggttagaacg attagaatgt tggtttaaca
    24361 ggtcaacacg gagttgattt ggccaccagt cgcgagtggt tgtgcccgcc cccgcgctct
    24421 ggtcgtgacc gccctgatgg aacgggcatt tgccagtggc tgtggtgtta tgaatatcgt
    24481 ctgacgtgct catcaatgtg ctcccctcta cagtgttacc gttacgatac acagcgttag
    24541 agagaagtta taattgaatt aatccacgga tgcgatagtt gagatcttac atattgttgg
    24601 ttaaagagat gtagatcaaa ttgatcgtaa ttaagctttt ttgattatgt ccgaattcgg
    24661 acaaatgctt tataaaaaag ggttttaggt tcatatcctt caagtaatga gggagaaaac
    24721 aaggctgata accttatttt cccgccctca tttcgaggca gcattttgtg ctctgtttaa
    24781 aatttgtgat cactgtgtga ttttcacaaa agccacacta tttataaacc aggtcgaaca
    24841 cccagcgtat ggcaaatcgc gtaactcatt tcagcgcggt taagcgtata gaagtggaaa
    24901 tctttcactc cttcacggct taaaatcttc accatatcca tggcaatatt cgctcccacc
    24961 agtttgcggg tttcggcatc gtcgtccagc ccgtcaaaca tttgtgccat ccacgccgga
    25021 atacgcacgt tggtcatatc ggcaaatttc ttcgcttgtt taaagttcga gaccggcaaa
    25081 attcccggaa taatttccac atcaataccc gccgatacgc agcggtcacg aaaacgcagg
    25141 tagctttcga catcaaagaa gaactgagta atcgcgcggt tggctccggc atcgactttg
    25201 cgtttcaggt tgagcaaatc cgcctgagcg ctttttgctt ccgggtgaac ctccggatac
    25261 gccgccacgg agatatcgaa atctgccact tcttttaaca gcgtcaccag gtcagaagca
    25321 tacatttccg gcttaccact tcccggcggc agatcgccac gcagcgccac gatatgacga
    25381 ataccgttat tccagtagtc gcgtgcaatg gtgcgcagct cgtcgggcgt cgcatcaatg
    25441 caagtaagat gcggtgccgc ttccagacca gtgcgatctt taatgccttt aataatgctg
    25501 tgcgtacggt cgcgctcgcc ggagttcgcg ccataggtca ccgatacaaa cttcggtttc
    25561 aggctgctaa ggcgatcgat ggagttccac agggtctgct ccatttcact ggtacgcggc
    25621 gggaaaaact cgaacgaaac gttaatctgc ccctggactt ctgccaggct ctgattcagg
    25681 gcatcccgct ggctggcgtg aaaaaagctc ataccttacc tcatcaatcg cttgtagtta
    25741 tatgttgtgt tgtgcacatc tatccgttta gacgtccaga tgtaaagatg aaggaaaagc
    25801 cgaagggcgt caaccgaaaa atgaccaatg atggtgagga aaaatcaggg aagatgaaaa
    25861 aacttcagga tggtaagaaa aagaaaatcc ggtatgcaaa gcaaaccgga ctgcaaatat
    25921 aaactaacca tgtacttatt gcttcttgcc ggattcgtcg taaacgctta atccggccta
    25981 atcctatgat aattcaatat atttcattag aaaccataaa cccgaaaaca tgagtaccgg
    26041 gcattattaa atttctgaaa ttacaacaac tgtgccagcc ggttgatatc cgactgaatc
    26101 gccccggcgg tgacgtcgcg ccccgcgcca ggcccacgga tcaccagcgg gttgtcgcga
    26161 taccagcggc tttcgatggc aaagacgtta tcgcacggca gcagtgatgc cagcggatgg
    26221 tcttcacgca ccgcctccac gcccacacgc gctttgccgt tggcatcgaa acgcgccacg
    26281 tagcgcagca ccagccccat ttcgcgggcc gcttccagcc gttgcaccat ctgctcgtta
    26341 agttcatcgc cattttcaaa gaaatggtcg atgctgccgc cttcgcaatg ggcaggcacc
    26401 agcgactcca cgcgtacctg atccggttcg atgttgtaac ctgcttcacg cgccagaatc
    26461 accagcttgc gcattacgtc tttgccggaa aggtcatcac gcgggtcagg ctcggttaac
    26521 ccttgctgcc acgcctgatc caccagctcg gtaaacggca cgctaccgtc gaattgcagg
    26581 aacagccagg agagcgtgcc ggagaagatc ccactgatcg acaaaatagt atcgccgctg
    26641 tcgatcagat cgcgcacggt atggttgatc ggcaagcccg ctccgacggt agcattgtac
    26701 agccagtgac gcccggtttt ttcgaaggcg tcgtggatct ggcgatattt attgctgtcg
    26761 ctggctcccg ccagtttgtt ggcgctgatg acgtggaaac cgtggctggc gaaatcaaga
    26821 tactgatcag caagctgctg gctggcggta acgtccagca ccactaaatc atcatacgga
    26881 tgggcgcgca tccacaggaa caacgactct tcatcctgct caaccgcttc atcgttgaag
    26941 aaggctaacg cgcggctggc gtccagcccg tcatagctca acaggctgcg gcggctgtcc
    27001 accacacctg ccagcacaaa ctcaaagccg gtacgtgccg aaagcgtgct ctgctcacgg
    27061 gcgaacagtt ccagccaacg ggaaccgata ttgcccttac cgaacaatac caggccgatg
    27121 cgtttttctg cgcggaagac ggactgatgc agcccctgaa tcaggctttc ggtcgggccg
    27181 gtgcgcagta ctgccaccag gctgatgccg tcatcggact gccaggtaaa ttcgaccggc
    27241 tggcctttca gttgctgcca gaagcggtgg caatgcagcg ggttacgggt gacgcctgca
    27301 ccgaccatcg ccaccagcgc cagcccctga cgcaggcgca gttcgccagg taatcccgct
    27361 tcgtcgagga ttttcagcgc actgtcggcc acttctgagg tgtagcaaaa ttgcagcaac
    27421 tggcgatcgt tatgtacgcc aaccgccagc gggcgtacct gcgcgcgttt caggatttgg
    27481 tcgatctctt tatgcgccag tttgaaatcc tgactggcgg gcacctgaaa ctcaatcaaa
    27541 cagacatcat cgtggctggt gacaatacgc gcaccagtac cggaggccag cacgcgttca
    27601 atgcgcgtgg aaccttgatc cggcgtgtag ctacagcgca gttgcaggtc gatttcgctg
    27661 ccagaaaccg gctgtaaagt acgggcgtga agaacgggag ccgccaggcg cgccagttcg
    27721 ctggcctcat ccagacgcag caacggcagc aggcaggcat ctttcacttt acgcgggtcg
    27781 gcactgtata ccccggcgac gtcgctccag atggttacgc gagaaacacc cgccagcgca
    27841 ccgatttgtg tcgcggaata gtcggaaccg ttacgcccca gcagcaccgt ttcaccggcg
    27901 ttgttgcggc tgataaatcc ggtcaccacc agacgtttgc ccggatgttg caccagcagc
    27961 tgttgcagca acgggtaaga aagcccttca tcaacctgcg gttgtgcggc gcgttcagcg
    28021 cgtaaaaact cgcgggcatc aagccaggcc gctggcagcc cttgttgatt aagtaccgca
    28081 gacatcaggc gtgccgacca cacttcaccg tgccccacca cttccgcata cactgcgtcg
    28141 ttaataccgc tgtcgagcag cgccgccagg cgctcaaggt cgctgacaaa agcgctaatg
    28201 aggctatcgg cttcttcagc gggtagcaga ccgctaatca gatcgcactg atagcgacgc
    28261 agcgtttgtt gaacctgatg cgcagagaga cgatcggtct ggcttagttt caaccagtta
    28321 atcaactggt tagtggtgct accggcggcg gaaaccacca tcatatcgtc aggctgagag
    28381 tactccgcca taatgcccgc gacacgcaaa taacacttca catcagccag actactgcca
    28441 ccaaatttat gcagctgacg acctttcgcc cctgcctgcg caatcacact catttttacc
    28501 ccttgtttgc agcccggaag ccattttcca ggtcggcaat taaatcttcg ccatcttcaa
    28561 taccggtgga gatacgcagc agcgtctcgg agatcccggc ggcagcacgc gcttctggtg
    28621 ccatgcctgc atgtgtcatg gttgcggcgt gagagattaa actttccact ccccctaatg
    28681 attccgccag cgtaaacaac gacagtccac ccaggaaacg acgcagcgtc tgctcatcgc
    28741 catccagttc aaaactcaac attgcgccat agcctttttg ctggcgcgcg gcaatttcat
    28801 gcccctgatt ttccggcagc gacgggtgat acagtttttt caccaacggc tgggtttgca
    28861 gatatttcac aatcgcctgc gcgttacgct gggccaactc catgcgcggc accagcgttc
    28921 gcaacccgcg tagcagcaga tagctgtcaa acgcgccgcc cgtcacgcca atattgtttg
    28981 cccaccaggc aagttcagtg acaacgtccg ggtctttagc aatcaccacg ccggccacca
    29041 cgtctgagtg accgttcaga tatttcgtgc atgaatgcaa caccagatcg gcacctaatg
    29101 ccagcggatt ttgtaatgcc gggcttaaga aggtgttatc caccacgctc accgccccga
    29161 cttcccttgc cagatggcag attttcgcaa tatccacgac gcgtaacaat ggattacttg
    29221 ggctttctac cagtaccagt ttgggtttat ctgccagcgc tgcccgtaat gcctgttcat
    29281 cgccttgatc aacaaacaac acgcgatagc aaccgcgttt cgccaggctg tcgaacaggc
    29341 gatagctacc gccgtagcag tcgtgcggcg ctaccagcag atcgccaggt ttcaaaaaga
    29401 cggtcgttac caggtgaatc gcggacatgc cggtattagt aagtactgca ccagcaccgc
    29461 cttccagttc tgccagtgct cgctgaacca catcgcgcgt tgggttgcca cgacgcgagt
    29521 aatcatgcgc gcgcggttca ttaaatccgg taaagttata ggtactggaa agatggatgg
    29581 gtgggacaac gcaaccatac tgttcgtcgt catttaaccc gctacgcact gcgatggtgg
    29641 cctgtttacg cgtcatgtga tgatgttccc tgggctttat tggtgaaatg tcaggcacca
    29701 gagtaaacat tgtggtaatg gacgtcaata catctggaca tctaaacttc tttgcgtata
    29761 gattgagcaa atcccaaata gccgttaaaa ttatatgcat tatcacgcca gcaggtggat
    29821 tacccgatgt cacggtagcg cctgtacggt aaactatgcg ggtttacggc cagtgcccac
    29881 attaactgtg tggtctggtc tcaatttatt gacgaagagg attaagtatc tcatggctga
    29941 atggagcggc gaatatatca gcccatacgc tgagcacggc aagaagagtg aacaagtcaa
    30001 aaagattacg gtttccattc ctcttaaggt gttaaaaatc ctcaccgatg aacgcacgcg
    30061 tcgtcaggtg aacaacctgc gtcacgctac caacagcgag ctgctgtgcg aagcgtttct
    30121 gcatgccttt accgggcaac ctttgccgga tgatgccgat ctgcgtaaag agcgcagcga
    30181 cgaaatcccg gaagcggcaa aagagatcat gcgtgagatg gggattaacc cggagacgtg
    30241 ggaatactaa agcggaaaag agcggcgcgg agtggaaccg cctgatgcgc tacgcttatc
    30301 aggcctacgt catattgcaa tttattgaat ttgcacgaac ttgtaggccg gataaggcgt
    30361 tcacgccgca tccggcataa acaacgagca cgttgtctgc gacccaccgc tttttataca
    30421 tggacgttta actatgaaaa acaggctgct gatcctcagc ctgctggttt ctgtacctgc
    30481 ctttgcctgg cagccgcaaa ctggcgacat catctttcaa atctctcgct catcgcaaag
    30541 taaagcgatc caactggcaa cccattccga ttacagccac accggtatgc tggtgatacg
    30601 caacaaaaag ccctacgttt ttgaagcggt cggcccggtg aaatacaccc cgctcaagca
    30661 gtggatcgcc catggtgaaa agggcaaata cgtcgttcgc cgcgttgaag gcggactgag
    30721 tgttgaacaa cagcaaaaac tggcgcaaac ggcaaaacgt tatctcggta aaccgtatga
    30781 tttcagcttc tcatggagcg acgatcgcca gtactgttcg gaagtggtgt ggaaggttta
    30841 ccagaacgcg ctgggaatgc gcgtgggcga acagcagaag ttgaaagagt ttgatctcag
    30901 caacccgctg gtccaggcga agctcaaaga acgctacggt aaaaatattc cgcttgagga
    30961 aacggtagtt tcaccacaag ccgttttcga cgcgccacaa ctcaccacgg ttgccaaaga
    31021 gtggccgctg ttttcgtggt aatggatgat gaaaaaaata attcccgccg tagtctgttt
    31081 gttgctttgt agttgcacga cctttccgca agctgtcgct ccggtaaacg gtgatgcctc
    31141 caattagttg aattaaggat ataatactcg cttttaaggt tgtttcatgg tcacagttaa
    31201 ccttcattgc ccccgttgcc agtccgttca ggtttaccgt cacgggcaga acccaaaaag
    31261 acatgatcga ttccgcggcc gtgactgtca ccgggtattt cagctcagtt actgttacga
    31321 gccccgtaaa ccgggagtta aagaccaaat cgctgaaatg actttcaacg gtgccggggt
    31381 tcgcgatact gcccgtacgc tgaaaatcgg cattaataca gtcatccgaa ctttaaaaaa
    31441 ctctcgccac gaagaataac gtcatccccg gtcgctcatg ctgatgtggc actcatctgc
    31501 aaacttagtc agcaatggag ctttgtcggc agtaaagcgc gacagcactg gctctggtac
    31561 gtgtacaaca cgaaaactgg tggtgttctg gcctacactt ttggcccccg gactgacgaa
    31621 acctgtcgtg aattgcgggc gctgcttacc cttttaccat cggcatgttg accactgacg
    31681 aatggggtag ttacgctaga gagttaccga aggagaagca tctgactggt aagattttta
    31741 ctcagcacat tgagcgtaac aatctgaccc tgagaacccg aatcaaacgt ctggcccgca
    31801 gaaccatctg tttctcgcgt tctgtagaac ttcatgaaaa agtcatcggt gcttttatcg
    31861 aaaatatatg ttctactaat tggagtcatc acccttctga taagctttcc ttggatgatt
    31921 accagactga atacacagcc aaagattttt acctcattct gctctttttt ctcaaatgac
    31981 atatattata ttt
//
LOCUS       DAZUDJ010000057        31142 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.057, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000057 DAZUDJ010000000
VERSION     DAZUDJ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31142
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.057"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(395..601)
                     /gene="ybfA"
                     /locus_tag="ACHY1N_003441"
     CDS             complement(395..601)
                     /gene="ybfA"
                     /locus_tag="ACHY1N_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HFS4045681.1"
                     /translation="MELYREYPAWLIFLRRTYAVAAGVLALPFMLFWKDRARFYSYLH
                     RVWSKTSDKPVWMDQAEKATGDFY"
     gene            914..1003
                     /gene="kdpF"
                     /locus_tag="ACHY1N_003442"
     CDS             914..1003
                     /gene="kdpF"
                     /locus_tag="ACHY1N_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HFS4045682.1"
                     /translation="MSAGVITGVLLVFLLLGYLVYALINAEAF"
     gene            1003..2676
                     /gene="kdpA"
                     /locus_tag="ACHY1N_003443"
     CDS             1003..2676
                     /gene="kdpA"
                     /locus_tag="ACHY1N_003443"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706533.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HFS4045683.1"
                     /translation="MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVER
                     ILFRLPGVSDHEMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLA
                     LNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
                     STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGD
                     RRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSL
                     FAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLV
                     SKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS"
     gene            2699..4747
                     /gene="kdpB"
                     /locus_tag="ACHY1N_003444"
     CDS             2699..4747
                     /gene="kdpB"
                     /locus_tag="ACHY1N_003444"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HFS4045684.1"
                     /translation="MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSL
                     LTTCISIAMASGAMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNE
                     IALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGV
                     AGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLA
                     DAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRM
                     IRKGSVDAIRRHVEANGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVK
                     GGIKERFAQLRKMGIKTVMITGDNRLTAAAIATEAGVDDFLAEATPEAKLALIRQYQA
                     EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGK
                     QMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFN
                     ALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
                     "
     gene            4756..5328
                     /gene="kdpC"
                     /locus_tag="ACHY1N_003445"
     CDS             4756..5328
                     /gene="kdpC"
                     /locus_tag="ACHY1N_003445"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HFS4045685.1"
                     /translation="MRGLRPALSTFIFLLLITGGVYPLLTTVLGQWWFPWQANGSLIR
                     EGDTVRGSALIGQNFTGNGYFQGRPSATAEMPYNPQASGGSNLAVSNPELDKQIAARV
                     AALRAANPDASTNVPVELVTASASGLDNNITPQAAVWQIPRVAKARNLSVEQLTQLIA
                     KYSQQPLVKYIGQPVVNIVELNLALDKLDE"
     gene            5321..8005
                     /gene="kdpD"
                     /locus_tag="ACHY1N_003446"
     CDS             5321..8005
                     /gene="kdpD"
                     /locus_tag="ACHY1N_003446"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdpD"
                     /protein_id="HFS4045686.1"
                     /translation="MNNEPLRPDPDRLLEQTAAPHRGKLKVFFGACAGVGKTWAMLAE
                     AQRLRAQGLDIVVGVVETHGRKDTAAMLEGLAVLPPKRQAYRGRHISEFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDEQMRAWRGHPGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASR
                     LGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDSRSFK
                     DKWRVQIQGCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVV
                     ATVINVVSYDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSPQDIAATSEQFIASTFHARSQVLLPDDNGKLQPLTHPQG
                     MTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMI
                     PEQQRLLETFTLLVANAFERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAE
                     IGIDAHVEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIV
                     DVHGGTITAFNRPEGGACFRVTLPQQTAPELEDFHEDM"
     gene            8002..8679
                     /gene="kdpE"
                     /locus_tag="ACHY1N_003447"
     CDS             8002..8679
                     /gene="kdpE"
                     /locus_tag="ACHY1N_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HFS4045687.1"
                     /translation="MTNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHSATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETG
                     IGYRFMP"
     gene            8841..8975
                     /locus_tag="ACHY1N_003448"
     CDS             8841..8975
                     /locus_tag="ACHY1N_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001417766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HFS4045688.1"
                     /translation="MIYYLGYDRFLLIFFTDYSHFMDRITLPSTDTARGKGKWKIITA
                     "
     gene            8954..9058
                     /gene="speFL"
                     /locus_tag="ACHY1N_003449"
     CDS             8954..9058
                     /gene="speFL"
                     /locus_tag="ACHY1N_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leader peptide SpeFL"
                     /protein_id="HFS4045689.1"
                     /translation="MENNNRLMPHIRRTTHIMKFAHRNSFDFHFFNAR"
     gene            9369..11567
                     /gene="speF"
                     /locus_tag="ACHY1N_003450"
     CDS             9369..11567
                     /gene="speF"
                     /locus_tag="ACHY1N_003450"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004586 - ornithine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase SpeF"
                     /protein_id="HFS4045690.1"
                     /translation="MSELKIAVSRSCPDCFSTHRACVNIDESNYIDVAVIILSVSDVE
                     RGKLDEIDATGYDIPVFIATENEERVPAEYLPRISGVFEHCESRKDFYGRQLETAASH
                     YETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLC
                     NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVL
                     FDRNNHKSNHHGALLQAGATPVYLETARNPYGFIGGIDAHCFEESYLRELIAEVAPQR
                     AKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCS
                     PLLLDLNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMH
                     ASTSPFYPLFAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELV
                     DGKPWQSYETAQIAVDLRFFQFVPGEHWHSFEGYAENQYFVDPCKLLLTTPGIDARNG
                     EYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLVRFEKLL
                     ESDAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRV
                     SMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFS
                     ALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRDAQSTLLKGEKL"
     gene            11564..12883
                     /gene="potE"
                     /locus_tag="ACHY1N_003451"
     CDS             11564..12883
                     /gene="potE"
                     /locus_tag="ACHY1N_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015496 - putrescine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0015822 - ornithine transport [Evidence
                     IEA];
                     GO_process: GO:0015847 - putrescine transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HFS4045691.1"
                     /translation="MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIP
                     VVGLCIIGWFWFSPTLYVDSWNPHHAPFFSAVGSSIAMTLWAFLGLESACANTDVVEN
                     PERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMELANSTAPFGLAFAQMFTPEVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSSDEGYFPKIFSRVTKVDAPVQGMLTIVIIQS
                     GLALMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKVANVPPSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            complement(12939..14579)
                     /gene="pgm"
                     /locus_tag="ACHY1N_003452"
     CDS             complement(12939..14579)
                     /gene="pgm"
                     /locus_tag="ACHY1N_003452"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004614 - phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucomutase
                     (alpha-D-glucose-1,6-bisphosphate-dependent)"
                     /protein_id="HFS4045692.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAARHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALMADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPQWGKDVAVGKTLVSSAMIDRVVNALGRKLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(14605..15150)
                     /gene="seqA"
                     /locus_tag="ACHY1N_003453"
     CDS             complement(14605..15150)
                     /gene="seqA"
                     /locus_tag="ACHY1N_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032297 - negative regulation of
                     DNA-templated DNA replication initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HFS4045693.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFSASSQPAAP
                     VTKEVRVASPAIVEAKPVKTIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLD
                     AQAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMI
                     EHIMQSMQFPAELIEKVRGTI"
     gene            15335..16099
                     /gene="ybfF"
                     /locus_tag="ACHY1N_003454"
     CDS             15335..16099
                     /gene="ybfF"
                     /locus_tag="ACHY1N_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFS4045694.1"
                     /translation="MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHN
                     IIQVDMRNHGLSPRDPVMNYPAMAQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALA
                     PDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQ
                     FLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPALFIPGGNSPYVSEQYRDDLL
                     AQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND"
     gene            16239..16532
                     /gene="ybfE"
                     /locus_tag="ACHY1N_003455"
     CDS             16239..16532
                     /gene="ybfE"
                     /locus_tag="ACHY1N_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HFS4045695.1"
                     /translation="MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKR
                     DKVRGLKRVELKLNAEAVEALNELAESRNMSRSELIEEMLMQQLAALRSQGIV"
     gene            16672..17202
                     /gene="fldA"
                     /locus_tag="ACHY1N_003456"
     CDS             16672..17202
                     /gene="fldA"
                     /locus_tag="ACHY1N_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HFS4045696.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQISEELHLDEILNA"
     gene            17412..17498
                     /gene="uof"
                     /locus_tag="ACHY1N_003457"
     CDS             17412..17498
                     /gene="uof"
                     /locus_tag="ACHY1N_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fur leader peptide"
                     /protein_id="HFS4045697.1"
                     /translation="MIRIISRANSVTSSNEVNRLVTGQIPHD"
     gene            17491..17937
                     /gene="fur"
                     /locus_tag="ACHY1N_003458"
     CDS             17491..17937
                     /gene="fur"
                     /locus_tag="ACHY1N_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HFS4045698.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK"
     gene            complement(18021..18347)
                     /gene="chiQ"
                     /locus_tag="ACHY1N_003459"
     CDS             complement(18021..18347)
                     /gene="chiQ"
                     /locus_tag="ACHY1N_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChiQ/YbfN family lipoprotein"
                     /protein_id="HFS4045699.1"
                     /translation="MKKLILIAIMASGLVACAQSTAPQEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKEKQHQQFADQESVRVLDYQQCLRATQTGNDQAVKADCDKVWQE
                     IRSNNK"
     gene            complement(18397..19803)
                     /gene="chiP"
                     /locus_tag="ACHY1N_003460"
     CDS             complement(18397..19803)
                     /gene="chiP"
                     /locus_tag="ACHY1N_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HFS4045700.1"
                     /translation="MRTFSGKRSTLALAIAGVTAMSGFMAMPEARAEGFIDDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSSHPNEIAFSKSNKAYDEDWSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGANFDYGDAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKV
                     DYLHSIGAKYDFKNNFVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRD
                     KVDDRSVNDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTEYDNHSDIPSWGGGYGNI
                     FQDERDVKFMVIAPFTIF"
     gene            complement(20249..21913)
                     /gene="glnS"
                     /locus_tag="ACHY1N_003461"
     CDS             complement(20249..21913)
                     /gene="glnS"
                     /locus_tag="ACHY1N_003461"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HFS4045701.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSD
                     YFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEK
                     MRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRAD
                     FREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADG
                     RKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSL
                     KDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE"
     gene            complement(22117..24063)
                     /gene="nagE"
                     /locus_tag="ACHY1N_003462"
     CDS             complement(22117..24063)
                     /gene="nagE"
                     /locus_tag="ACHY1N_003462"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HFS4045702.1"
                     /translation="MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVAFIAQA
                     GGAIFDNLALIFAIGVASSWSKDSAGAAALAGAVGYFVLTKAMVTINPEINMGVLAGI
                     ITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGFFCLVLAAIFGYVWPPVQHAIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGV
                     TEPLEFLFMFLAPLLYLLHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAS
                     QNVWMLLVMGVVFFAIYFVVFSLVIRMFNLKTPGREDKEDEIVTEEANSNTEEGLNQL
                     ATNYIAAVGGTDNLKAIDACITRLRLTVADSARVNDTMCKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDAMKKVVARGPVAAASAEATPATAAPVAKPQAVPNAVSIAELVSPITGD
                     VVALDQVPDEAFASKAVGDGVAVKPTDKIVVSPAAGTIVKIFNTNHAFCLETEKGAEI
                     VVHMGIDTVALEGKGFKRLVEEGAQVSAGQPILEMDLDYLNANARSMISPVVCSNIDY
                     FSGLIIKAQGHVVAGQTPLYEIKK"
     gene            24396..25196
                     /gene="nagB"
                     /locus_tag="ACHY1N_003463"
     CDS             24396..25196
                     /gene="nagB"
                     /locus_tag="ACHY1N_003463"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFS4045703.1"
                     /translation="MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGT
                     PMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKICSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEG
                     CVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL"
     gene            25256..26404
                     /gene="nagA"
                     /locus_tag="ACHY1N_003464"
     CDS             25256..26404
                     /gene="nagA"
                     /locus_tag="ACHY1N_003464"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFS4045704.1"
                     /translation="MYALTQGRIFTGHEFLDDHAVVIADGLIKSVCPVAELPPEIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNYLPTLITT
                     SDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLC
                     ENADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLY
                     NAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRM
                     ATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITKTIVNGNEVVTQ"
     gene            26413..27633
                     /gene="nagC"
                     /locus_tag="ACHY1N_003465"
                     /gene_synonym="nagR"
     CDS             26413..27633
                     /gene="nagC"
                     /locus_tag="ACHY1N_003465"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HFS4045705.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDATITL
                     FDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDP
                     DSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGRHLGKTIAIAINLFN
                     PQKIVIAGEITEADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKR
                     AMLNGILLQHLLEN"
     gene            27681..28433
                     /gene="nagD"
                     /locus_tag="ACHY1N_003466"
     CDS             27681..28433
                     /gene="nagD"
                     /locus_tag="ACHY1N_003466"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HFS4045706.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLHGIMDKGLPLVLLTNY
                     PSQTGQDLANRFATAGVDVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSSLDDIDSMPFRPSWIYPSVAEIDVI"
     gene            28690..30354
                     /gene="asnB"
                     /locus_tag="ACHY1N_003467"
     CDS             28690..30354
                     /gene="asnB"
                     /locus_tag="ACHY1N_003467"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HFS4045707.1"
                     /translation="MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNA
                     ILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEV
                     ILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVAS
                     EMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDFDAVKDNVTDKNELRQALED
                     SVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLP
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFESYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPL
                     PSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK"
     gene            30735..30811
                     /locus_tag="ACHY1N_003468"
     tRNA            30735..30811
                     /locus_tag="ACHY1N_003468"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30769..30771,aa:Met,seq:cat)
     gene            30820..30904
                     /locus_tag="ACHY1N_003469"
     tRNA            30820..30904
                     /locus_tag="ACHY1N_003469"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30854..30856,aa:Leu,seq:tag)
     gene            30928..31002
                     /locus_tag="ACHY1N_003470"
     tRNA            30928..31002
                     /locus_tag="ACHY1N_003470"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30960..30962,aa:Gln,seq:ttg)
     gene            31018..31094
                     /locus_tag="ACHY1N_003471"
     tRNA            31018..31094
                     /locus_tag="ACHY1N_003471"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31052..31054,aa:Met,seq:cat)
BASE COUNT         7360 a         7893 c         8151 g         7738 t
ORIGIN      
        1 ggattgaccg gatggccgga cgtcactccg ccggggcacc ccgaacaggc cacaccggtt
       61 ggggcaccga tgcgcacccc ggctgaaccc tgaacaatgc taccgccata ctgcgtcatg
      121 tcgccctgac gcgccgccgg ttttccgctc atctgctcat ccttgtttta tcgggttatt
      181 tgtctgctga caggcgaaac cctacagatt tataagaaag ccttaagtga gatatctgtc
      241 agataagaac aattaggaaa atatttatat atatttcatg aatatatgtt tcgattggta
      301 taacgatgtc taaatattcc tctgaacatc ttcctgatac aaaaaaccgc cagcgtttcc
      361 gctggcggtt ttcaatgtat tcaaaactca gcaatcaata aaaatcacca gttgcctttt
      421 cggcctgatc catccacacc ggtttatcgc tggttttcga ccagacgcga tgcaggtagc
      481 tgtaaaagcg ggcgcggtct ttccagaaaa gcatgaaagg cagcgccaga acgcccgctg
      541 caaccgcata agtacggcgt aaaaagataa gccatgcagg atattctctg tagagttcca
      601 tacttttctc ccccttttgt atctacccgg tgaatggcac cggaaaaatg aatttgttta
      661 tctgatgaaa atagtaccgc cttttgtgta attttactac tcatccgacc acttattttt
      721 gcttattgat ggtttattta cattcatcct gtaattaagt tacacaaaag ttaaattaat
      781 actaaacatt agttaaatca tggcttttgc catttttata ctttttttac accccgcccg
      841 cagatttttg cgaaatcttt gcagccagaa ttctaccctt ccggtatcac ttttaggcca
      901 ctggaggtgc actgtgagtg caggcgtgat aaccggcgta ttgctggtgt ttttattact
      961 gggttatctg gtttatgccc tgatcaatgc ggaggcgttc tgatggctgc gcaagggttc
     1021 ttactgatcg ccacgttttt actggtgtta atggtgctgg cgcgtccttt aggcagcggg
     1081 ctggcgcggc tgattaatga cattcctctt ccaggtacag cgggcgttga acgtatactc
     1141 tttcgtttac ctggcgtctc tgaccatgag atgaactgga agcaatatct ttgtgccatt
     1201 ctcggcctga acatgctggg gctggcggtg ctgtttttta tgttgctcgg tcagcactat
     1261 ctgccgctta atccacagca gttgccgggg ctgtcgtggg atctggcgct gaataccgcc
     1321 gtcagctttg tcacgaatac caactggcaa tcttacagcg gtgaaaccac gttgagctat
     1381 ttcagccaga tggctggctt aacggtgcaa aactttcttt ctgccgccag cgggattgcg
     1441 gtgatttttg ccctcatccg tgcgtttacc cgccagagca tgagcacact cgggaatgcc
     1501 tgggtcgatc tgctacgcat cacgttatgg gtgctcgtcc ctgtggcgtt gttgatcgca
     1561 ctgtttttta ttcaacaagg tgcgctgcaa aactttcagc cttatcaggc tgtgaatacc
     1621 gttgaaggag cgcaacagct gttacccatg gggcctgtag cttctcagga agcgatcaag
     1681 atgctcggta ctaacggcgg tggcttcttt aatgccaact cgtcgcatcc gtttgaaaac
     1741 ccaaccgcac tgaccaactt cgtgcagatg ctggcgatct tcttgatccc aacggcgctg
     1801 tgctttgcct ttggtgaagt gacgggcgat cgccgccagg ggcgcatgtt gctgtgggcg
     1861 atgtcagtga tttttgtcat ctgcgtaggc gtggtgatgt gggcagaagt tcagggtaat
     1921 cctcatctgc tggcgctcgg cgcagacagc agcatcaata tggaaggtaa agagagccgt
     1981 ttcggcgtgc tggtcagtag cctgtttgcg gtcgtgacta cggcggcttc ctgtggcgcg
     2041 gtgattgcga tgcatgattc gtttaccgct ctcggtggca tggtgccgat gtggctgatg
     2101 caaattggtg aagtggtgtt cggcggtgtc ggttctggtc tttacggcat gatgctgttt
     2161 gtcctgctgg cggtgtttat tgccgggctg atgattggtc gtacaccgga atatctgggt
     2221 aaaaaaatcg acgtacgcga gatgaaactg actgcactgg cgattctggt taccccgacg
     2281 ctggtgctga tgggcgcggc gctggcaatg atgaccgacg ccggacgtag cgccatgctc
     2341 aaccctggcc cgcatggttt tagcgaagtg ctgtacgccg tgtcatccgc cgctaacaac
     2401 aacggcagcg cctttgccgg attaagcgcc aactccccgt tctggaactg tttactggcg
     2461 ttctgcatgt ttgtcggtcg cttcggggtg attatcccgg tgatggcaat tgccggttcg
     2521 ctggtgagta aaaagagcca acccgccagc tccggcacgc tgccaacgca cggcccgctg
     2581 tttgttggcc tgttaatcgg caccgtgttg ctggttggcg cactgacctt tatccctgcc
     2641 ctggcgcttg gtccggtggc ggaatatctc tcctgatgat attgagtgag cactgaatat
     2701 gagtcgtaaa caactggcgc tattcgaacc aacacttgtc gttcaggcgc tgaaagaagc
     2761 ggtgaaaaaa ttaaacccgc aggcgcaatg gcgcaatccg gtgatgttta tcgtctggat
     2821 cggcagtctg ctgaccacct gtattagcat cgcgatggca agcggtgcga tgcctggcaa
     2881 tgcgctgttt agcgcggcaa ttagcggctg gctgtgggtc accgtactgt tcgctaattt
     2941 cgccgaggcg ctggcagaag gccgcagtaa agcgcaggcc aacagtctta aaggggtgaa
     3001 aaaaactgcc tttgcccgca agctgcgtga gccgaaatat ggcgctgcgg cggacaaagt
     3061 tcctgccgat caactgcgta aaggtgacat cgtgctggta gaagctggcg atattatccc
     3121 ctgcgatggt gaagtcattg aaggcggcgc atcggtcgat gaaagcgcca tcaccgggga
     3181 atcggcaccg gtgatccgtg aatccggcgg cgattttgcc tccgtcaccg gcggcacgcg
     3241 tattctttct gactggctgg tgattgagtg tagcgttaac cccggtgaga catttctgga
     3301 tcggatgatc gcgatggtgg aaggcgcaca gcgacgcaaa acaccgaacg agattgccct
     3361 gactatcctg ctgattgctc tgaccatcgt ctttttactg gcaaccgcca cgctgtggcc
     3421 gttttccgcg tggggcggta atgccgtgag tgtaacggta ctggtggcgc tgctggtctg
     3481 tctgatccca accactattg gcggcctgtt gtcagcgatc ggcgtcgccg ggatgagtcg
     3541 gatgctgggc gcgaatgtga ttgccaccag cggacgtgca gttgaagcgg caggtgacgt
     3601 tgacgttctg ctactggata aaaccggcac catcacactc ggtaaccgtc aggcgtcgga
     3661 gtttatccct gcgcagggcg tggatgaaaa aacgctggct gacgccgcac aactggcttc
     3721 gctggctgat gaaacgccgg aaggccgcag tattgtgatc ctcgccaagc aacgttttaa
     3781 cctgcgcgag cgcgatgtgc agtcgctcca tgccaccttt gtaccgttta ctgcgcaaag
     3841 ccggatgagc gggatcaaca tcgacaaccg catgatccgt aaaggttctg tcgatgccat
     3901 tcgccgccat gttgaggcta acggcggtca cttccctacc gatgttgatc aaaaagtcga
     3961 tcaggttgcg cgtcaggggg ccacgccgct ggtggtggtg gaaggttccc gtgtgctggg
     4021 cgttattgcg ctgaaagata tcgtcaaagg cggtattaaa gagcgcttcg cccagctgcg
     4081 caaaatgggc attaaaacgg tgatgattac cggcgataac cgtctgactg ccgccgccat
     4141 tgctacggaa gcgggcgtcg atgattttct cgccgaagcg acaccggagg ccaagctggc
     4201 attgattcgt cagtatcagg cggaaggccg tttggtggcg atgaccggcg acggcaccaa
     4261 cgatgctcca gcgctggcgc aggcagatgt cgcggtggcg atgaactccg gtactcaggc
     4321 ggcgaaagaa gcgggcaata tggtcgatct cgactctaac ccgaccaagt tgatcgaggt
     4381 ggtacatatt ggcaaacaga tgctgatgac ccgtggctcg ctgaccacct tcagcattgc
     4441 caacgatgtg gcgaaatact tcgccattat tccggcggcg ttcgcggcaa cgtatccgca
     4501 gttaaatgcg ctgaacatca tgcgccttca ttcgcccgac tccgccattc tcagtgcggt
     4561 cattttcaac gccttgatta tcgtcttttt gattcctctg gcgttaaaag gcgtgagtta
     4621 taaaccgctt accgcttctg ccatgttgcg ccgtaactta tggatttacg gtctgggtgg
     4681 gctgctggtg ccgtttattg gtatcaaagt cattgattta ctgctgaccg tttgcggtct
     4741 ggtgtgaggt ttaccatgcg tggcttacgt ccggcattat cgacatttat ctttctgtta
     4801 ttgattactg gcggcgttta cccgctgctg accaccgtgc tggggcaatg gtggtttccc
     4861 tggcaggcca acggttcgtt gattcgtgaa ggtgatacgg tgcggggttc ggcattaatc
     4921 gggcagaatt ttaccggcaa cggctatttt cagggtcgcc cgtcggcaac ggcagaaatg
     4981 ccctataatc cacaggcttc tggcgggagc aatctggcgg tcagtaaccc tgagctggat
     5041 aaacaaatag ccgcacgcgt tgctgcatta cgggccgcta acccggatgc cagtacgaac
     5101 gttccggttg aactggtgac ggcatcggca agcgggctgg acaataatat caccccgcaa
     5161 gcggcggtct ggcaaatccc acgcgtggcg aaagcgcgta atctcagcgt tgaacagctc
     5221 acgcaactga tcgcaaaata cagccaacaa ccgctggtga aatatatcgg ccagccggtc
     5281 gtcaacattg ttgaactcaa tctggcgctg gataaacttg atgaataacg aacccttacg
     5341 tcccgacccc gatcgtctgc tggaacaaac tgccgcgccg catcggggga agctgaaagt
     5401 tttcttcggt gcctgtgcag gcgtcgggaa gacctgggcg atgctggcag aagcccagcg
     5461 actgcgggcg caagggctgg atattgtggt tggcgtggta gaaacccatg ggcggaaaga
     5521 taccgccgcc atgcttgaag ggctggctgt tctgccgccc aaacgccagg cgtaccgtgg
     5581 gcggcatatc agcgagtttg atctcgatgc cgccctcgcc cgccgtccgg cgctgatctt
     5641 aatggacgaa ctggcgcaca gtaatgcgcc aggttctcgt catcctaaac gctggcagga
     5701 tatcgaagaa ctgctggaag ctggcattga tgttttcaca accgtcaacg ttcagcatct
     5761 ggaaagtctg aatgatgtgg tcagcggcgt caccggaatt caggtacggg aaaccgtgcc
     5821 cgatcctttt ttcgatgccg ccgacgacgt agtgctggtg gacttgcccc cggacgatct
     5881 gcgccagcgg ctgaaagaag gcaaagtcta tattgccggg caggcggagc gcgccattga
     5941 acattttttc cgcaaaggca atctgatcgc cctgcgtgaa ctggcactgc gccgtactgc
     6001 cgatcgcgta gatgagcaaa tgcgcgcctg gcgggggcat cctggtgaag agaaagtgtg
     6061 gcacacgcgc gacgcgatcc ttttatgcat cgggcataac accggcagtg agaaactggt
     6121 ccgcgcggcg gcgcggttgg cctcgcgcct gggtagcgtc tggcacgcgg tgtatgttga
     6181 aacccctgcc ctgcatcgct taccggaaaa aaaacgtcgg gcaattctca gcgccttacg
     6241 tctggcgcag gagctgggcg cggagacggc tacactttct gatccagcgg aagaaaaagc
     6301 agtagtgcgt tatgcccgtg aacataatct cggcaagatt attctcggtc gcccggcctc
     6361 gcgccgctgg tggcgtcggg aaacgtttgc tgaccgactg gcgcgcatcg cccccgatct
     6421 cgatcaggtg ctggtcgcgc ttgatgaacc acccgcccgc acgattaaca acgcgccgga
     6481 tagccgctct tttaaagaca agtggcgggt acagattcag ggatgcgtgg ttgccgccgc
     6541 gttatgcgcc gttatcactt taattgccat gcagtggctg atggcgtttg atgccgccaa
     6601 cctggtgatg ctgtatctgc ttggcgtggt ggtggtggcg ctattttatg gacgctggcc
     6661 ttcggtggtt gctaccgtca ttaatgtggt gagttacgat ctctttttta tcgccccacg
     6721 cggcacgctc gctgtctctg atgtgcaata tctgctgacc ttcgcggtga tgttaaccgt
     6781 cgggctggtg atcgggaacc ttactgcggg tgtgcgttat caggcgcggg tagcccgtta
     6841 ccgcgagcaa cgcacacggc acttatatga aatgtcgaaa gctctggcgg tgggccgcag
     6901 tccgcaggac atcgccgcca ccagcgaaca atttattgcc tccacgtttc atgcccgcag
     6961 tcaggtgttg ttgcccgatg acaacggtaa attgcagccg ttaacacatc cgcaaggaat
     7021 gacgccatgg gacgatgcca tcgcgcagtg gagttttgat aaaggcctgc ctgcgggtgc
     7081 gggcaccgac acgttacccg gcgtgccgta ccagattttg ccgctaaaaa gcggcgagaa
     7141 aacctacgga ctggtggtgg tggaaccggg gaatctgcgt cagttgatga tcccggagca
     7201 gcagcgcctg ctagagacgt ttacgctgtt agtcgccaat gcgtttgagc ggctgacgct
     7261 gaccgccagt gaagaacagg cgcggatggc aagcgaacgt gaacagatcc gcaacgccct
     7321 gctggcggcg ctttcgcatg atttacgcac gccgcttacg gtgctgtttg gtcaggcaga
     7381 aatcttaacg ctcgatctgg caagcgaagg atcgccccac gcccgccagg ccagcgagat
     7441 tcgtcagcat gtgctgaaca ctacccgact ggtgaataat ctactggata tggcgcgaat
     7501 tcagtccggc ggctttaatt tgaagaaaga gtggttaacg ctggaagaag tagtcggcag
     7561 cgcgctgcaa atgctggaac cgggtttatc gtcgcccatc aatctttctc tgccagaacc
     7621 gctgacctta atccacgttg acgggccact ctttgaacgg gtgctgatta atctgctgga
     7681 gaacgcggtg aaatatgcgg gtgcgcaggc cgaaattggt atcgatgccc acgttgaggg
     7741 cgaaaatcta caactggatg tctgggataa cggccccggt cttccgccag gccaggagca
     7801 gacgatattt gataagtttg ctcgcgggaa taaagagtcg gcagtaccgg gggtagggct
     7861 tggactggca atttgtcggg cgatagtgga tgtacacggg ggcactatta ccgcgttcaa
     7921 ccgaccggaa ggtggtgcct gttttcgtgt tacacttccc cagcaaaccg ctcctgaact
     7981 tgaagacttt catgaggata tgtgacaaac gttctgattg ttgaagatga acaggctatt
     8041 cgtcgctttc tgcgcacggc gctggagggc gacgggatgc gcgtctatga ggccgaaacg
     8101 ctgcaacgcg gcttgctgga agcggctacc cgtaagccag atttgattat tctcgatctc
     8161 ggcctgcccg atggtgatgg gattgagttt atccgcgacc tgcgccagtg gagcgcggtg
     8221 ccggtgattg tgctttccgc acgcagcgaa gagagcgaca aaatcgccgc gctggatgcc
     8281 ggagcggatg attatctgag taagccgttt ggcattggcg aattgcaggc ccgtctgcgc
     8341 gtcgctttac gccgccactc cgccaccgcc gcgcccgatc cgctggtgaa attttccgat
     8401 gttaccgtcg atttagccgc ccgcgtgatt caccggggtg aggaagaggt gcatctcaca
     8461 ccgattgagt tccgcctgct ggcggtgctg ctgaataatg ccgggaaagt gctcacccag
     8521 cgccagttac tcaatcaggt gtgggggcca aacgcggtcg aacacagtca ctatttgcgt
     8581 atttatatgg gacatctgcg acaaaaactg gaacaggatc ccgctcgccc ccgccatttc
     8641 attactgaaa ccggtattgg gtatcggttt atgccatgaa tgtttattca ataaatgcgc
     8701 ttaaataatt attaatttat tattaaacct gccaaaaata ttattatttg gcaggtttaa
     8761 tttcttaacg caaatataaa acacaaaatt acaacattta aataacaaaa cagcatctaa
     8821 tatggcgcta ttcataatta atgatttatt atttggggta tgatcgtttt ttgttgatct
     8881 tcttcacaga ttatagccat ttcatggata gaataactct accttcaact gacacagcaa
     8941 gaggtaaagg taaatggaaa ataataaccg cttaatgcct catataaggc ggacaaccca
     9001 tatcatgaag tttgcccatc gtaatagttt tgactttcat ttctttaatg cccgctagtc
     9061 ttctgactaa agggcacccc aacgtacagg tctccctgac tttaagcatt acaggttaat
     9121 acctgtattc ctcggtgctc atatactgct aaccctttta aactctaaat aattcgagtc
     9181 gcagcacttg caacttgagg tatgacgagt atagccagtt accgggctgg tctgggttat
     9241 tgcatctgca aaaagcaaac tactgattta tttatcagcg gtggagcttt gctttttttc
     9301 cggcgtgatc gatttctcct ttgagaaatt gaggacctgc tattacctga aataaagaga
     9361 tgaacaaaat gtcagaatta aaaattgccg ttagtcgttc ttgcccggat tgtttttcca
     9421 ctcatcgtgc atgcgtgaat atagacgaaa gtaattatat tgacgttgcc gtcattattt
     9481 tatcagtcag tgatgttgaa cgtggaaaac tcgatgaaat agacgctact ggctatgaca
     9541 ttcctgtttt tattgcaacg gaaaatgaag aacgtgtacc cgcagaatat ctgccacgta
     9601 tttctggtgt cttcgaacat tgcgaatcac gtaaagattt ttatggacgt cagttagaaa
     9661 ccgctgccag ccattatgaa acgcaactgc gcccgccctt cttccgcgca ctggtcgatt
     9721 atgttaatca gggcaatagt gcttttgact gccctggtca tcaggggggt gagtttttcc
     9781 gtcgccatcc ggcaggcaat cagttcgtgg aatactttgg cgaaatgctc ttccgctctg
     9841 acttgtgtaa tgctgacgta gcaatgggcg atctgctgat tcatgaaggt gcgccatgta
     9901 ttgcacaaca gcatgcggct aaagtcttta atgccgataa aacctatttc gttttaaacg
     9961 gtacttcatc ttctaataaa gtggtcttaa acgcattgct gacgccgggc gatctggtgt
    10021 tgtttgaccg caataaccat aaatctaacc accacggtgc gttgctacag gctggcgcga
    10081 caccggttta tctggaaacc gcacgtaacc cgtatggctt tatcggtggc attgatgcgc
    10141 actgttttga agaaagttac ctgcgtgagc tgatcgcgga agtcgcaccg cagcgggcaa
    10201 aagaggctcg tcctttccgc ctcgctgtga ttcagttagg cacctacgac ggtacgattt
    10261 ataacgcccg ccaggtggtg gataaaattg gtcatctgtg tgactacatt ctgtttgact
    10321 ccgcatgggt tggctatgag caatttatcc cgatgatggc tgactgttcg ccgctgttgc
    10381 tggatcttaa tgagaacgat ccgggtattc tggttacgca atccgtacat aaacagcagg
    10441 ctggtttttc tcaaacttca caaatccata aaaaagacag ccacatcaaa gggcaacagc
    10501 gttatgtacc gcacaaacgc atgaacaacg cctttatgat gcatgcctcc accagcccgt
    10561 tctatccgct gtttgccgca ctggatatca acgccaaaat gcatgaaggt gtcagcggtc
    10621 gtaatatgtg gatggattgt gtggtaaatg gcattaatgc ccgcaagctg atcctcgata
    10681 actgtcagca tattcgtccg ttcgtacctg aactggtgga tggtaaaccc tggcagtcgt
    10741 atgaaacagc gcaaattgcg gttgatctgc gcttcttcca gtttgtacca ggtgagcact
    10801 ggcactcttt tgaaggctat gcagagaatc aatactttgt cgatccatgc aaactgttgc
    10861 tgacaacccc aggtattgat gcacgtaacg gcgaatatga agcgttcggt gtacccgcga
    10921 cgattcttgc taacttcctg cgcgaaaatg gcgtagtgcc ggaaaaatgc gatcttaact
    10981 ccatcctctt cctgctgact ccggcagaag atatggccaa gcttcagcaa cttgttgccc
    11041 tgctggtacg cttcgaaaaa ctgcttgagt ccgacgcgcc attagcagaa gtgctgcctt
    11101 ccatctacaa acagcatgaa gagcgctacg ccggttatac cctgcgtcag ttgtgtcaag
    11161 aaatgcatga tttgtatgcc cgtcacaacg tgaaacaact gcaaaaagag atgttccgta
    11221 aggaacactt cccacgcgta agcatgaatc cgcaagaagc caactacgcc tatttacgcg
    11281 gtgaagtgga gctggttcgt ctgccggatg cagaaggccg tatcgctgcc gaaggtgcgc
    11341 ttccttatcc tccgggtgtg ctgtgtgttg ttccgggtga aatctggggt ggtgctgttt
    11401 tgcgttactt cagcgctctg gaagaaggga tcaacctgct gccaggtttt gcaccggagc
    11461 tgcagggtgt ctatatcgaa gaacatgatg gtcgtaagca agtttggtgc tatgtcatca
    11521 agcctcgtga tgcgcaaagc accctgttga aaggggaaaa attatgagtc aggctaaatc
    11581 gaacaaaatg ggcgtcgttc agttaaccat actgacgatg gtcaacatga tgggctccgg
    11641 tatcatcatg ctgccgacaa agcttgccga agttgggaca atttcaatta tctcctggct
    11701 ggtgacagcc gtaggctcaa tggcactggc atgggcattc gcaaaatgcg gtatgttcag
    11761 ccgtaaatca ggcggtatgg gcggttatgc ggagtatgct ttcggtaaat ccggtaactt
    11821 tatggcgaac tatacctacg gcgtctcgct gctgattgct aacgtcgcga ttgctatttc
    11881 ggcggttggt tacggcaccg aactgctcgg cgcgagtttg tcgccagtgc agattggtct
    11941 tgcgaccatc ggggtgctgt ggatttgtac cgtggctaac tttggtggtg cgcgcattac
    12001 cgggcaaatc agtagcatta ccgtgtgggg ggtcattatt ccggtggtag gcctgtgcat
    12061 tatcggctgg ttctggttta gcccgacgct ttacgttgat tcctggaatc cgcatcatgc
    12121 accgttcttc agtgcagtag gttcttccat cgctatgacg ctgtgggctt ttctcggtct
    12181 ggagtctgcg tgtgcgaata ctgatgtagt ggaaaacccg gaacgtaatg tgccaatcgc
    12241 ggtactcggc ggtacgttag gtgcggcggt gatttatatc gtctccacca acgtgattgc
    12301 agggattgtg cctaatatgg agctggcaaa ttcaacggca ccatttggcc tggccttcgc
    12361 acagatgttc acaccagaag tgggtaaagt cattatggcg ctgatggtga tgtcctgctg
    12421 cggttcgctg cttggctggc agttcaccat tgcccaggtg tttaaatctt catctgatga
    12481 aggctacttc cctaaaattt tctcccgtgt aaccaaagtg gatgcaccgg tgcagggaat
    12541 gttgaccatt gtgattatcc agagcgggtt ggcgctgatg acgattagcc cgtcgctaaa
    12601 cagtcagttc aacgtgctgg ttaacctggc cgtggtgacc aatatcattc cgtatattct
    12661 gtcaatggcg gcattagtca ttattcagaa ggtcgctaat gtgcccccct caaaagcgaa
    12721 agttgcaaac tttgttgctt ttgttggcgc gatgtatagc ttttatgcgc tgtactcatc
    12781 cggggaagaa gccatgctgt acggttccat cgtgaccttc cttggttgga cactgtatgg
    12841 tctggtatca ccacgctttg aactgaaaaa taaacacggt taaaaaagca aagtaaaaaa
    12901 gggcgatctt gcgaccgccc tttttttatt aaatgtgttt acgcgttttt cagaacttcg
    12961 ctaacaatct caaccgcttc tttctcaatc tgcttgcgat gttcttcacc gaggaagctt
    13021 tcgcagtaga tcttatatgc gtcttccgtg cctgacggac gcgcggcgaa ccagccgttg
    13081 tcagtcatca ctttcagacc gccgatagaa gcaccattac ccggtgccgc cgtcagacgt
    13141 gcggtgatcg ggtcacctgc cagggtgctg gcgctcacca tttccggaga cagcttagac
    13201 aacgccgctt tttgtgcgga agtcgcagcg gcctgcaaac ggttgtagct cggcgcacca
    13261 aagcgttttg ccagttcgtt gtagtgttcc tgcgggttct taccggtgac agcggtgatt
    13321 tccgccgcca gcagacacat aatgatgccg tctttatcgg tggaccacgg cgtgccgtcg
    13381 aaacgcagga aggaagcccc ggcgctctct tcgccgccaa agccgaaact gccgtcgaac
    13441 agaccatcaa caaaccattt gaatcctacc gggacttcta ccagtttacg gcccaaggcg
    13501 ttgaccacac ggtcgatcat cgcagaagaa accagcgttt taccgacagc aacatctttg
    13561 ccccactgcg gacgatgctg gaacaggtag ttgatcgcca ccgccaggta gtggttcgga
    13621 ttcatcaaac ctgccggagt gacgataccg tgacggtcat aatccgggtc gttagcaaac
    13681 gccagatcga acttatcacg cagtgccagc aggcccgcca tcgcacactc ggaggagcag
    13741 tccatacgga tcgcgccgtc tttatcaagg tgcataaagc ggaaggtttg atcgacctga
    13801 tcgttaacga tggtcaggtt gaggttgtaa tactcgccaa tacgcttcca gtattcgata
    13861 ccggaaccgc ccagcggatc aacgccaagc gtcaggcccg ctttctgaat cgccgccata
    13921 tcaacgatat cggccagacc ttccacaaac ggctgcacca gatcctgctc tttcacatga
    13981 ccggatgcca tcgcttcgtc gagagagata cgcttcacgc ctttcaggcc atcggccatc
    14041 agtgcgttgg ccctgtcttc caccactttg gtgacgttgg tatcagccgg gccaccattt
    14101 ggcgggttgt acttgatacc accatcttcc ggcgggttat gggacggtgt aatcacgata
    14161 ccgtctgcca gcgggccacc ttttttattg tgaaccagga tggcattgga aacggcaggc
    14221 gtcggagtga atccattgtt ttcctgcaca atgacatcaa cgccgttcgc tgccagcact
    14281 tccagtacgg aaatgaacgc aggctcggac agggcgtgag tatctttacc cacatagcaa
    14341 gggccagtga tgccattttt cgcacgttct tcagcaattg cctgagcgat cgccagaatg
    14401 tgcggctcgt taaagctgtg gcgcgctgca ctgccacggt gaccggaagt accgaatttc
    14461 accgcgtgct ccgcattccc tgcttctggt ttcagtacat aatattgcgc cgtcagttgg
    14521 gcgacgttaa tcaaatcact ctgttgtgca ggttggcctg cacgattgtg gattgccatt
    14581 gctttgtcct ttgtctgcaa cgttttagat agttccgcga accttctcaa tcaattccgc
    14641 cgggaattgc atcgactgca tgatgtgttc gatcatgctg catttacggc cggtgttggt
    14701 gttggtgatc acccaatacg gcgtgcctgg cacatgtttc ggcttggtct gattaccatt
    14761 tttcagcagc gtttgttcat ctgccgcaaa gtaaacgcgt gtacgaccgt gcaacgattc
    14821 cgttgcttcg gcaaacgcct gggcgtcaag agaatatagt gtagacaaca gcagcataaa
    14881 gcgattgacc gctcgctttt gctctgcgta ttcgtccgaa agcagaagtt cacgcattgc
    14941 gcgaaccttg tctttaatcg ttttgaccgg cttcgcttcg acgatagcag gtgacgcaac
    15001 gcgaacctct ttcgtcaccg gagcagcagg ctgtgatgag gcggaaaatt tcaacatacg
    15061 ccgtaaaatg tcggatgcgc tctcgccgat atgcttagtg tggctggcaa tatagctgta
    15121 gagttcatca tcaacttcaa tcgttttcat cttaatccag tgcagtgtct tagctgaata
    15181 caagtcgcca ggagtatatg aataaatccc ggcagcggat agcgtcaagc ctggcttgca
    15241 gaaaaactcg gaataaacct tatttgttgc agccctgtgg cacaatggtc aacataatac
    15301 cctaacccga caacgcgaaa aaaagaactt tgccatgaaa ttgaatatcc gcgcgcaaac
    15361 tgcacaaaac cagcacaata attctcccat cgttcttgtc catggtctgt ttggtagcct
    15421 cgacaacctt ggcgtactgg ctcgcgatct ggtaaacgat cacaatatca tccaggttga
    15481 tatgcgtaac cacggtcttt caccgagaga tccggtaatg aattacccgg cgatggcgca
    15541 ggatcttgtt gatactctgg atgcacagca gatcgacaaa gcaacattta tcggtcactc
    15601 catgggcggt aaagcggtaa tggcacttac tgcactggcc cccgatcgca tcgataaact
    15661 ggtggcgatc gatatcgcac cggtcgacta tcacgtacgc cgtcatgatg agattttcgc
    15721 ggctatcaac gcggtcagtg aatcggacgc acaaactcgc cagcaagcag cagcaataat
    15781 gcgccagcat cttaatgaag aaggggtgat tcagtttctg ttgaaatctt ttgttgacgg
    15841 ggagtggcgc tttaacgtgc cggtattgtg ggatcagtat ccgcatattg tgggttggga
    15901 gaaaatcccg gcatgggatc accctgccct gtttatccct ggcggcaatt ctccgtatgt
    15961 tagcgagcag taccgtgatg atttactggc acaatttcca caggcacggg cgcatgtgat
    16021 tgcaggcgcg ggtcactggg tccatgctga aaaaccggat gcggtattac gcgctatccg
    16081 tcgctatctc aatgattaac gcaactgatt aaaaacccag cgtccgcgtc gctttccgcg
    16141 cgtgggcgtt ggcgtgactc atcgcgctga tgtattatgg cgcgctatcc atccgggcag
    16201 aggcctggct gattgtttcc cccgaagtca ccaagatcat ggccaaagaa caaacggacc
    16261 gtacgacatt agatctgttc gcgcacgagc gtcgaccggg acgaccgaaa actaatccgc
    16321 tttcgcgcga tgaacagctg cgtattaata aacgcaacca gctaaaacgc gacaaagtac
    16381 gtggccttaa gcgtgtcgaa ctgaagctga acgcggaagc tgtcgaggcg ctgaacgagc
    16441 tggcggagtc gcgcaatatg agccgtagcg aactgatcga agagatgtta atgcagcaac
    16501 tggcggcgct gcgtagtcag ggcatcgttt aaatttccac tttcatgtag cacagtgtgc
    16561 agtcctgctc gtttgctgat tccgcaagac tgcctgttct gctatgattg cctttatccg
    16621 tgggcaattt tccaccccca tttcaataag tttcaagagg ttatttcact catggctatc
    16681 actggcatct ttttcggcag cgacaccggt aataccgaaa atatcgcaaa aatgattcaa
    16741 aaacagcttg gtaaagacgt tgccgatgtc catgacattg caaaaagcag caaagaagat
    16801 ctggaagctt atgacattct gctgctgggc atcccaacct ggtattacgg cgaagcgcag
    16861 tgtgactggg atgacttctt cccgactctc gaagagattg atttcaacgg caaactggtt
    16921 gcgctgtttg gttgtggtga ccaggaagat tacgccgaat atttctgcga cgcattgggc
    16981 accatccgcg acatcattga accgcgcggt gcaaccatcg ttggtcactg gccaactgcg
    17041 ggctatcatt tcgaagcatc aaaaggtctg gcagatgacg accactttgt cggtctggct
    17101 atcgacgaag accgtcagcc ggaactgacc gctgaacgtg tagaaaaatg ggttaaacag
    17161 atttctgaag agttgcatct cgacgaaatt cttaatgcct gatgtgatgc ggcgtagact
    17221 catgtctacg ccgtattaat agataatgcc aatcaaaata attgctacaa atttgtaact
    17281 tttgctgttg tacctgtaca atgtcccggt gttcaagtgg ccttgccgtt gtaaatgtaa
    17341 gctgtgccac gtttttatta acaatatttg ccagggactt gtggttttca tttaggcgtg
    17401 gcaattctat aatgatacgc attatctcaa gagcaaattc tgtcacttct tctaatgaag
    17461 tgaaccgctt agtaacagga cagattccgc atgactgata acaataccgc cctaaagaaa
    17521 gctggcctga aagtaacgct tccacgttta aaaatcctgg aagttcttca ggagccggac
    17581 aaccatcacg tcagtgcgga agatttatac aaacgtctga tcgatatggg tgaagaaatt
    17641 ggtctggcta cggtatatcg cgtactgaac cagtttgacg acgctggtat cgtcacccgc
    17701 cacaattttg aaggcggtaa atccgtattt gaactgacac agcaacatca ccacgatcac
    17761 ctgatttgcc tcgactgcgg caaggttatc gaatttagtg atgattccat cgaagcgcgt
    17821 cagcgtgaaa ttgccgcaaa acatggcatt cgcctgacta accacagtct ctatctttac
    17881 ggtcactgtg ccgaaggcga ttgccgcgaa gatgagcacg cgcacgaagg caaataagcc
    17941 agcctgaacg agaaaagcca acctgcgggt tggctttttt atacaaggga aataagaaaa
    18001 gcgagagtta cagctctcac ttatttgtta ttactgcgta tttcctgcca gaccttatca
    18061 caatcggctt tcaccgcctg atcatttccg gtttgcgttg cacgcagaca ctgctgataa
    18121 tccagtacgc gtacactttc ctggtcggca aactgctgat gttgtttctc tttcttcagc
    18181 acgtttaaca cgctctggca ggcttcaatt ttttctggcg aaccttgtgc ggtgttgata
    18241 caggcgctgt atgcctcttt cagacgactg tcttcctgtg gcgcggttga ttgcgcacaa
    18301 gctaccagcc ccgatgccat tatggcgatg agaatcagtt ttttcatagc aaattcctca
    18361 aacgtgcggc aggcacaaaa cctgccgcgt cgggcatcag aagatggtga atggtgcgat
    18421 taccataaat ttcacgtcac gctcatcctg gaagatgtta ccgtaaccgc cgccccagct
    18481 tgggatgtca gagtggttgt cgtattcggt gaagtgcagt ttgaacatcg tgcctttggc
    18541 gcgaccgtcc tgaatggtgt agaccgcatc caggctgtag gcagactctt caatagtccg
    18601 gtttttgtcg tagtacgcat ccggattgct ctgccaggtc gcaggtttag catcccatgc
    18661 gtaaacgtag gaagcgccga tggcgaagcc tggaagattc cagtttttca ggtcatacat
    18721 cgcaccgaag aagaccgctt tttcgccgtt ggcgttgaag tcggaacggt tatcccacca
    18781 gatatccagg cggccgttgg aggaagcgta ggttggagtc atacgttgca ggaagtatcc
    18841 ctgctgaccg tcagccttaa cccaggtgcc ttcgaggcgc aaatccacta cgtcagccgc
    18901 ccggtaacca aaggtcaacg cttgcagcca ggcggtgccg tcataaaggt cgttgacgct
    18961 gcgatcgtca actttatcgc gcgtaccata gaactggtag ctggtggtta acgggctacc
    19021 ggcgatatca aatttgtagc tggctttggc aaaatattga tcgatatacc cttccgcctg
    19081 accaaatgcc gcttccagta cgaagttatt tttgaagtcg tatttcgcac cgatggagtg
    19141 caggtaatca actttggtgg ttttatcgtt ctgataaaac tcatccattt ccagatgcca
    19201 cggcgctttg tattcgttgg tccacatgta ggagaaactc aaggcaccag catcgccgta
    19261 atcaaaattc gccccggctt ccgccccctg ataagtacct ggcataaagc tccagtgcgg
    19321 cgctaacagc gtttgaccag ttggctgaat gtaacctgcc ctcgcccaaa ccggaccgta
    19381 tttaaatttg gccgcagctt tatacaggct tataccgctt ttgtcgccgg accagtcttc
    19441 gtcataggct ttattacttt ttgaaaacgc gatttcgttc gggtgggagc tgtcgccgtt
    19501 ttccgccatt tcaatcgccg taaacgcagc aatatcaagg ccgaacatat cagcagcata
    19561 accggactga aaatcgaggt tggcattcca ggtggagtga gaaaggttgg ttttgtattt
    19621 gtcgccgtcg gtaacatctt tacggtcgcg ttcacgctgc cagtaatata taccgccggt
    19681 taaggttgaa tcgtcgatga atccttcggc gcgagcctcc ggcattgcca taaagcccga
    19741 cattgctgta acaccggcga tagccagcgc cagcgtacta cgtttgccac taaacgtacg
    19801 catgggttaa tcctctttga cgtataaatt gctgcaccaa aggtgaacag cgaaaaaata
    19861 aaaattaaaa aagtagcgtt gagaaaagtc tcgctgacta caggaacaga ctatttttcg
    19921 cgacgcgaat tatcaatctc tttctgtaac cagaatgtaa gaacatgagc aaccgcacat
    19981 attttgatga tttttgttac aaggcttaag tttgcggttg aaaggcttgc agaagaataa
    20041 aagcgtgaat ttccagcaag atgaaagcgg ttacatttta tttaattatg gtttgtgatt
    20101 ttaaatttat tttatggata aattgcgaag cggaattaat tcgcgaagaa aagcagaaaa
    20161 aacgccgcag agtgcggcgt ttgggattgt ttgctatttc ttgccggatg cgacgtaaat
    20221 gcctcacccg gcctggtaga acttaaaatt actcgcctac tttcgcccag gtatcacgca
    20281 gcccaacggt gcggttaaat accggttttt ccgctgtgga atggcggctg tcgaggcaga
    20341 agtaaccttc acgctcaaac tggaatgctt tacccgcaac cgcatctttc agcgacggtt
    20401 cagcaaagcc ctgtttgatc accagcgatt ccgggttaat caccgacagg aaatcatccg
    20461 cagcaccagg gttcggcacg ctgaacagac ggtcgtacag acggatttca accggcagcg
    20521 catgtgccgc gctcacccag tgaataacac ctttgacttt acgaccatct gccggatctt
    20581 tgcttaaggt gtcggcgtca taagtacaga agatggtggt gatattgcct tcggcatctt
    20641 tctccacgcg ttcagcctta atgacgtaag cattacgcag acgcacttct ttacccagca
    20701 ccagacgttt gtactgcttg ttagcttctt cgcggaaatc ggcgcgatcg atccaaatct
    20761 caccgctaaa cggcacctga cgactcccca tttccggttt gttcggatgg ttcggcatgg
    20821 tgaccatttc gccttcgccc tgatagtttt cgataaccag tttcaccgga tcgataaccg
    20881 ccattgcgcg cggcgcattt tcgttgagat cttcacggat gcaggattcc agcgatgcca
    20941 tctcaatggt gttgtcctgc ttggtcacgc cgatgcgttt gcagaactca cgaatagaag
    21001 cagcagtgta accacgacga cgcagaccgg aaatggtcgg catacgcggg tcatcccagc
    21061 cttcaacgtg cttgtcggtc accagcaggt tcagcttacg cttggacatc acagtgtatt
    21121 ccagattcag gcgcgagaat tcgtactggc gcgggtgaac aggaatggtg atgttgtcca
    21181 gcacccagtc gtacaggcga cggttgtcct gaaactcaag cgtacacaga gagtgcgtaa
    21241 taccttccag ggcatcgctg atgcagtggg tgaagtcgta catcgggtag atgcaccact
    21301 tgttgccagt ctggtggtgt tcagcaaatt taatacggta cagcaccgga tcgcgcatca
    21361 cgataaacgg tgaagccatg tcgattttcg cacgcaggca ggctttacct tcttcaaaac
    21421 caccggcacg cattttttcg aacagcgcca ggttctcttc aacgctgcgg tcgcggtacg
    21481 ggctgttttt acccggttgc gtcagggtgc cgcggtattc gcggatctgt tccggcgtca
    21541 gttcatcaac gtacgccagg cctttattga tcagttcgat cgcataggcg tggagctgat
    21601 caaaataatc ggaggagtaa cggacgttac cagaccagtg aaaacctaac cactctacgt
    21661 cgtttttgat cgactcaaca tactcgatat cttcttttac cgggttagtg tcgtcgaaac
    21721 gcaggttgca ctggccttta tagtcctggg cgatcccgaa gttcaggcag atagatttcg
    21781 catggccaat atgcagatag ccattcggct ccggcgggaa acgggtgtgt actgtggtgt
    21841 gcttaccact ggccagatct tcatcgatga tctgacggat aaagttagtc gggcgggctt
    21901 ctgcctcact catcgtggat tcctcaaagc gtaaacaacg tataacggcg tatgatctta
    21961 taagcgggac aggctgacaa ctgttagttt tttaaaattg ataatctaac aaggattatg
    22021 gggatgattg atgaaaaaaa aaagcggcag agaagatctc caccgcttgt cattgttgga
    22081 tgcgacgctc aagcgtcgca tcaggcataa agcagattac tttttgattt catacagcgg
    22141 tgtttgaccc gccacaacat ggccctgagc tttaatgatc aagccactga aatagtcgat
    22201 attgctgcaa accaccgggc taatcatcga gcgggcgtta gcgttcaggt aatccagatc
    22261 catttccaga atcggttgcc ctgcgcttac ctgcgcaccc tcttccacca gacgtttaaa
    22321 gcctttacct tccagcgcta cggtgtcgat acccatatgg acgacgatct ccgcgccttt
    22381 ttcggtttcc aggcagaacg cgtggttggt gttgaagatt ttcacgattg tccctgcggc
    22441 tggtgatacg acgattttat ctgtcggttt caccgccaca ccgtcaccca ccgctttgct
    22501 ggcgaatgct tcgtcaggaa cctgatccag tgccacgaca tcaccggtaa tcggcgatac
    22561 cagctccgcg atagataccg cgtttggtac agcctgcggt tttgctacag gcgcggcagt
    22621 tgccggagtt gcttcagctg acgcagcggc taccggacca cgggcaacga ctttcttcat
    22681 cgcatcgccg atggattctg ctttcgcgcc aacaatcacc tgaatagtct gtttgttcag
    22741 tttcactaca ccagaagcac ccagacgttt acacatcgta tcgttgacgc gggcagagtc
    22801 agccacggtc aggcgcagac gggtgataca ggcgtcaatt gctttcaggt tgtcagtgcc
    22861 gccaaccgca gcaatatagt tggtcgccag ttgattgagg ccttcttcag tgttgctgtt
    22921 ggcttcttca gtaacgatct cgtcttcttt atcttcacga cccggcgttt tcaggttgaa
    22981 catgcggata accaaactga acaccacgaa gtagatagcg aagaagacaa cacccataac
    23041 cagcagcatc cagacgttct ggctggcggc cggcaggtta tacatcaacg cgtagtcgat
    23101 agcccccgca gagaaagaga agccagcatg gatacccagc agtgttgcca caaacaggct
    23161 gataccggtc agcagtgcgt gcaggaggta cagcagcggt gcaaggaaca tgaacaggaa
    23221 ttccagcggc tcagtcacac cggtcaggaa cgcagtaaca gcaacagaaa gcagcatccc
    23281 gccaaccatc ggacgacgct ctttcggtgc tgcgaagtac atcgccagcg ccgcacccgg
    23341 cagaccgaac atcataatcg ggaagaagcc ggacatgaac atccccgcgg tgccgtcacc
    23401 ggcatagaag cggttgatat caccgtggaa aaccgtaccc gccgcgttgg tgaattcacc
    23461 aatctggaac caggcgatgg tgttcagcac ctgatgcaga ccggttggga tcagcagacg
    23521 gttgatgaaa ccaaagatac cggaacccag cgcgcccgca gaaacgatcc actcgcctcc
    23581 tgcatggata gcgtgctgta ccggcggcca gacgtaacca aaaatggccg ccagcaccag
    23641 gcagaagaag ccggtggcaa tcggcacaaa gcgtttgccg ccgaagaaac tcaggaagtc
    23701 cggcagttta atatcggacc aacggttata ggctgcgcca ccaaccagac cggtaatgat
    23761 acccgccagt acacccatgt taatttctgg gttgatggtc accatcgctt tggttaacac
    23821 aaagtaacct accgcacccg ccagcgccgc cgcacctgcg ctgtctttcg accagctgga
    23881 tgccacaccg atggcgaaga ttaatgcgag gttatcaaaa atcgcaccgc ccgcctgggc
    23941 aataaacgca acgttaagta aatctggctg accgaatcgc agcaacagtg ccgccaccgg
    24001 cagcaccgcg atagggagct gtaacgccct accgagtcgc tggaaaaaac ctaaaatatt
    24061 catcttattc cccctacgag aaccctattt ggctcgttta aagccgtatt tttattttgc
    24121 tgcaaattgt actgccgatg ttctgtaatc agattgttag atcatctgct acagagtgtg
    24181 tgaaaattta attcgtatcg caaattaaac gcgtgtcttt tgtgagtttt gtcaccaaat
    24241 atcgttatca tcactccctt ttactggcta aagcagaaaa cttattttat cattcaaaaa
    24301 atcaggtcgg attgacgcct gtctgcgcaa atccaggtta cgcttaaaga tgcctaatcc
    24361 gccaacggct tacattttac ttattgaggt gaataatgag actgatcccc ctgactaccg
    24421 ctgaacaggt cggcaaatgg gctgctcgcc atatcgtcaa tcgtatcaat gcgttcaaac
    24481 cgactgccga tcgtccgttt gttctgggcc tgccgactgg cggcacgccg atgaccacct
    24541 ataaagcgtt agtcgaaatg cataaagcag gccaggtcag ctttaagcac gttgtcacct
    24601 tcaacatgga cgaatatgtc ggtctgccga aagagcatcc ggaaagctac tacagcttta
    24661 tgcaccgtaa tttcttcgat cacgttgata ttccagcaga aaacatcaac cttctcaacg
    24721 gcaacgcccc ggatatcgac gccgaatgcc gccagtatga agaaaaaatc tgttcttacg
    24781 gaaaaattca tctgtttatg ggcggtgtag gtaacgacgg tcatattgca tttaacgaac
    24841 cggcgtcttc tctggcttct cgtactcgta tcaaaacctt gactcatgac actcgcgtcg
    24901 cgaactctcg tttctttgat aacgatgtca atcaggtgcc aaaatatgcc ctgactgtcg
    24961 gtgttggtac attgctggat gccgaagaag tgatgattct ggtgctgggt agccagaaag
    25021 cactggcact gcaggctgca gttgaaggtt gcgtgaacca catgtggacc atcagctgtc
    25081 tgcaactgca tccaaaagcg atcatggtgt gcgatgaacc ttccaccatg gagctgaaag
    25141 ttaagacttt aagatatttc aatgaattag aagcagaaaa tatcaaaggt ctgtaattgt
    25201 tatccctgcc ctggctcctt gctcagggca atatttttta aaatcggggg tcagaatgta
    25261 tgcattaacc cagggccgga tctttaccgg ccacgaattt cttgatgacc acgcggttgt
    25321 tatcgctgat ggcctgatta aaagcgtctg tccggtagcg gaactgccgc cagagatcga
    25381 acaacgttca ctgaacgggg ccattctctc ccccggtttt atcgatgtgc agttaaacgg
    25441 ctgcggcggc gtacagttta acgacaccgc tgaagcggtc agcgtggaaa cgctggaaat
    25501 catgcagaaa gccaatgaga aatcaggctg tactaactat ctgccgacgc ttatcaccac
    25561 cagcgatgag ctgatgaaac agggcgtgcg cgttatgcgc gagtacctgg caaaacatcc
    25621 gaatcaggcg ttaggtctgc atctggaagg tccgtggctg aatctggtaa aaaaaggcac
    25681 ccataatccg aattttgtgc gtaagcctga tgccgcgctg gtcgatttcc tgtgtgaaaa
    25741 cgccgacgtc attaccaaag tgaccctggc accggaaatg gttcctgcgg aagtcatcag
    25801 caaactggca aatgccggga ttgtggtttc tgccggtcac tccaacgcga cgttgaaaga
    25861 agcaaaagcc ggtttccgcg cggggattac ctttgccacc catctgtaca acgcgatgcc
    25921 gtatattacc ggtcgtgaac cgggcctggc gggcgcgatc ctcgacgaag ctgacattta
    25981 ttgcggtatt attgctgatg gcctgcatgt tgattacgcc aacattcgta acgctaaacg
    26041 tctgaaaggc gacaaactgt gtctggttac cgacgccacc gcgccagcag gtgccaacat
    26101 tgaacagttc atttttgcgg gtaaaacaat atactaccgt aacggacttt gtgtggatga
    26161 gaacggtacg ttaagcggtt catccttaac catgattgaa ggcgtgcgta atctggtcga
    26221 acattgcggt atcgcactgg atgaagtgct gcgtatggcg acgctctatc cggcgcgtgc
    26281 gattggcgtt gagaaacgtc tcggcacact cgccgcaggt aaagtagcca acctgaccgc
    26341 attcacacct gattttaaaa tcaccaagac catcgttaac ggtaacgagg tcgtaactca
    26401 ataagagaaa gtatgacacc aggcggacaa gctcagatag gtaatgttga tctcgtaaaa
    26461 cagcttaaca gcgcggcggt ttatcgcctg attgaccagt acgggccaat ctcgcggatt
    26521 cagattgccg agcaaagcca gcttgccccc gccagcgtaa ccaaaattac gcgtcagctt
    26581 atcgaacgcg ggctgatcaa agaagttgat cagcaggcct ccaccggggg ccgccgcgct
    26641 atctccatcg tcaccgaaac ccgcaatttc cacgcaatcg gcgtacggct tggtcgtcac
    26701 gacgccacca tcaccctgtt tgatctcagc agcaaagtgc tggcagaaga acattacccg
    26761 ctgccggaac gtacccagca aacgctggaa catgccctgt tgaatgccat tgctcagttt
    26821 attgatagct accagcgcaa actgcgcgag ctgatcgcga tttcggtgat cctgccaggg
    26881 cttgttgacc cggacagcgg caaaattcat tacatgccgc atattcaggt agaaaactgg
    26941 gggctggtag aagcactgga agaacgtttt aaagtgacct gtttcgttgg tcacgatatc
    27001 cgtagtctgg cgctggcgga gcactacttc ggtgcaagtc aggattgcga agactccatt
    27061 ctggtgcgtg tccatcgcgg aaccggggcc gggattatct ctaacgggcg catttttatt
    27121 ggccgcaacg gcaacgtcgg tgaaattggc catattcagg tcgaaccgct gggtgaacgc
    27181 tgccactgcg gcaactttgg ctgcctggaa actatcgctg ccaacgccgc tattgaacaa
    27241 cgggtgttga atctgttaaa gcagggctac cagagccgcg tgccgctgga cgactgcacc
    27301 atcaaaacta tctgcaaagc cgcgaacaaa ggcgatagcc tggcctcgga agtgattgag
    27361 tatgtcggtc gtcatctggg caaaaccatc gccattgcta tcaacttatt taatccgcaa
    27421 aaaattgtta ttgccggtga aatcaccgaa gccgataaag tgctgctccc tgctattgaa
    27481 agctgcatta atacccaggc gctgaaggcg tttcgcacta atctgccggt ggtacgttct
    27541 gagctggatc accgctcggc aatcggcgct tttgcgctgg taaaacgcgc catgctcaac
    27601 ggtattttgc tccagcattt gctggaaaat taatgtgctt ttatagtggc gcttattgtt
    27661 gtcaatattc tgggtagtcc atgaccatta aaaatgtaat ttgcgatatc gacggcgtgc
    27721 tgatgcacga taacgtcgcc gtaccgggtg cagcggaatt tttgcacggg attatggata
    27781 aaggcctgcc gctggtgttg ctgaccaact atccttcgca gaccgggcaa gatctggcga
    27841 accgctttgc cactgccggt gtcgatgtgc cggatagcgt gttttatacc tctgcgatgg
    27901 cgactgccga tttcctgcgt cgccaggaag gcaagaaagc gtatgtggtg ggcgaaggcg
    27961 cactgattca tgaactgtac aaagccggtt tcactattac cgatgtgaac cctgattttg
    28021 tgattgttgg cgaaacgcgt tcctacaact gggacatgat gcataaagcg gcctatttcg
    28081 tcgctaacgg tgcacgcttt atcgccacca acccggacac ccacgggcgc ggtttttatc
    28141 ccgcttgtgg cgcgttgtgt gcagggattg agaaaatctc cgggcgcaaa ccgttctatg
    28201 ttggtaagcc cagcccgtgg atcatccgcg cggcattaaa caaaatgcag gcgcattcgg
    28261 aagaaacggt gattgtcggc gataacttgc gcaccgacat tctggcgggc ttccaggcgg
    28321 gtctggagac gattctggtg ctttctggtg tttcatcgct cgacgatatc gacagtatgc
    28381 cgttccgccc aagctggatt tacccgtcgg tcgctgaaat cgacgttatc tgaatagcaa
    28441 ccacgtctca gggcgtggtt tcttattttt acccatcatt aaaatcatcc cattcaataa
    28501 aactcgccaa aaattatcga tccatcaata aatacatcac cacaccctcc cctttttcac
    28561 aaatcagcaa tcaccattac gttttttatt tttgcactgc caaatcgctt gcgcacggtg
    28621 ctgctttacg gcattttttt aaacaagcaa acacaacaag caacaaatac caggttaacg
    28681 gagaaggtta tgtgttcaat ttttggcgta ttcgatatca aaacagacgc agttgagctg
    28741 cgtaagaaag cactcgagct gtcacgcctg atgcgtcatc gtggcccgga ctggtccggt
    28801 atttatgcca gcgataacgc cattctcgcc cacgaacgtc tgtcaattgt tgacgttaac
    28861 gcgggggcgc aacctctcta caaccaacaa aaaactcatg tgctggcggt aaacggtgaa
    28921 atctacaacc accaggcact gcgcgccgaa tatggcgatc gttatcagtt ccagaccgga
    28981 tctgactgcg aagtgatcct cgcgctgtat caggaaaaag ggccggaatt tctcgacgac
    29041 ttgcagggca tgtttgcctt tgccctgtac gacagcgaaa aagatgcata tctgattggt
    29101 cgcgaccatc tggggatcat cccactgtat atgggctatg acgagcacgg tcagctgtat
    29161 gtggcctcag aaatgaaagc cctggtgcca gtttgccgca cgattaaaga gttcccggcg
    29221 gggagctatt tgtggagtca ggacggcgaa atccgttctt attatcatcg cgactggttc
    29281 gactttgatg cagtgaaaga taacgtgacc gacaaaaacg agctgcgtca ggcactggaa
    29341 gattccgtta aaagccatct gatgtctgac gttccttacg gtgtgctgct ctcgggtggt
    29401 ctggattcct caattatttc cgcgatcacc aagaaatacg ccgcccgtcg cgtggaagat
    29461 caggaacgct ctgaagcctg gtggccgcaa ttacactcct ttgctgtagg tctgccgggt
    29521 tcaccggatc tgaaagcagc ccaggaagtg gcaaaccatc tgggcacggt gcatcacgaa
    29581 attcacttca ctgtacagga aggtctggat gccatccgcg acgtgattta ccacatcgaa
    29641 acctatgatg tgacaactat tcgcgcttca acaccgatgt atttaatgtc gcgtaagatc
    29701 aaggcaatgg gcattaaaat ggtgctgtcc ggtgaaggtt ctgatgaagt gtttggcggt
    29761 tatctttact tccacaaagc accgaatgcc aaagaactgc atgaagagac ggtgcgtaaa
    29821 ctgctggccc tgcatatgta tgactgcgcg cgcgccaaca aagcgatgtc agcctggggc
    29881 gtggaagcac gcgttccgtt cctcgacaaa aaattccttg atgtggcgat gcgcattaac
    29941 ccgcaggata aaatgtgcgg taacggcaaa atggaaaaac acatcctgcg tgaatgtttt
    30001 gagtcatacc tgcccgcaag cgtggcctgg cggcagaaag agcagttctc cgatggcgtc
    30061 ggttacagtt ggatcgacac cctgaaagaa gtggcggcgc agcaggtttc tgatcagcaa
    30121 ctggaaactg cccgcttccg cttcccgtac aacacgccaa cctcaaaaga agcgtatctg
    30181 taccgggaga tctttgaaga actgttcccg cttccgagcg ccgctgagtg cgtgcctggc
    30241 ggtccttccg tcgcgtgttc ttccgctaaa gcgattgagt gggatgaggc gttcaagaaa
    30301 atggacgatc cgtctggtcg tgcggttggc gttcaccagt cggcgtataa gtaagaaatg
    30361 cgaaacagcc ccggtgaaat ccggggctgt ttcagttatt gaggtgcttg ttaattctga
    30421 tatgcagtaa ggaaatgttc cgggtttgcc acatcactgt ttgacaactc atcactgtag
    30481 gccagtattt catagattaa tttcccacca ctattgttga attccgaatt tcatcctgta
    30541 cgacaaaaga atggctgtag ggtggggaaa aaacacaaag taaacaataa ttgacgaata
    30601 tagcgccacg ctgttcgcaa cctaaccaaa cagtcacttt cgagcaattt tccttgaaaa
    30661 agaggttgac gctgcaaggc tctatacgca taatgcgccc cgcaacgccg ataaggtatc
    30721 gcgaaaaaaa agatggctac gtagctcagt tggttagagc acatcactca taatgatggg
    30781 gtcacaggtt cgaatcccgt cgtagccacc atcttttttg cgggagtggc gaaattggta
    30841 gacgcaccag atttaggttc tggcgccgca aggtgtgcga gttcaagtct cgcctcccgc
    30901 accattcacc agaaagcgtt gtacggatgg ggtatcgcca agcggtaagg caccggtttt
    30961 tgataccggc attccctggt tcgaatccag gtaccccagc catcgaagaa acaatctggc
    31021 tacgtagctc agttggttag agcacatcac tcataatgat ggggtcacag gttcgaatcc
    31081 cgtcgtagcc accaaattct gaatgtgtcg aatacgttcg gcaaattcaa aaaccaattt
    31141 gt
//
LOCUS       DAZUDJ010000058        30948 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.058, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000058 DAZUDJ010000000
VERSION     DAZUDJ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30948
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.058"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..89)
                     /locus_tag="ACHY1N_003472"
     rRNA            complement(<1..89)
                     /locus_tag="ACHY1N_003472"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(533..3106)
                     /gene="clpB"
                     /locus_tag="ACHY1N_003473"
     CDS             complement(533..3106)
                     /gene="clpB"
                     /locus_tag="ACHY1N_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFS4045708.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQEL
                     HHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKEL
                     VLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDE
                     ALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAV
                     Q"
     gene            complement(3236..3967)
                     /gene="yfiH"
                     /locus_tag="ACHY1N_003474"
     CDS             complement(3236..3967)
                     /gene="yfiH"
                     /locus_tag="ACHY1N_003474"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004000 - adenosine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphorylase YfiH"
                     /protein_id="HFS4045709.1"
                     /translation="MSKLIVPQWPLPKGVAACSSSRIGGVSLPPYDSLNLGAHCGDNP
                     DHVEENRKRLFAAGNLPSKPVWLEQVHGKDVLKLTGEAYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPR
                     AFEVGVEVREAFMAVDAKASAAFIQHGDKYLADIYQLARQRLANVGVEQIFGGDRCTY
                     TENETFFSYRRDKTTGRMASFIWLI"
     gene            complement(3964..4944)
                     /gene="rluD"
                     /locus_tag="ACHY1N_003475"
     CDS             complement(3964..4944)
                     /gene="rluD"
                     /locus_tag="ACHY1N_003475"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HFS4045710.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQR
                     VLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDEDIIVINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISMLRKFDR
                     QALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDWL"
     gene            5079..5816
                     /gene="bamD"
                     /locus_tag="ACHY1N_003476"
     CDS             5079..5816
                     /gene="bamD"
                     /locus_tag="ACHY1N_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HFS4045711.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFIRLNPTH
                     PNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAEYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLM
                     ENAYRQMQMNAQAEKVAKIIAANSSNT"
     gene            6087..6428
                     /gene="raiA"
                     /locus_tag="ACHY1N_003477"
     CDS             6087..6428
                     /gene="raiA"
                     /locus_tag="ACHY1N_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFS4045712.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFVADATINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAATSVK
                     DANFVEEVEEE"
     misc_feature    6531..6656
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            6532..6579
                     /gene="pheL"
                     /locus_tag="ACHY1N_003478"
     CDS             6532..6579
                     /gene="pheL"
                     /locus_tag="ACHY1N_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pheA operon leader peptide PheL"
                     /protein_id="HFS4045713.1"
                     /translation="MKHTPFFFAFFFTFP"
     gene            6678..7838
                     /gene="pheA"
                     /locus_tag="ACHY1N_003479"
     CDS             6678..7838
                     /gene="pheA"
                     /locus_tag="ACHY1N_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004106 - chorismate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HFS4045714.1"
                     /translation="MTSENPLLALREKISALDEKLLALLAERRELAVEVGKAKLLSHR
                     PVRDIDRERDLLERLITLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNKINPH
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIEN
                     TSSGAINDVYDLLQHTSLSIVGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSK
                     FLNRYPHWKIEYTESTSAAMEKVAQAKSPHVAALGSEAGGTLYGLQVLERIEANQQQN
                     FTRFVVLARKAINVSDQVPAKTTLLMATGQQAGALVEALLVLRNHNLIMTRLESRPIH
                     GNPWEEMFYLDIQANLKSAEMQKALKELGEITRSMKVLGCYPSENVVPVDPT"
     gene            complement(7881..9002)
                     /gene="tyrA"
                     /locus_tag="ACHY1N_003480"
     CDS             complement(7881..9002)
                     /gene="tyrA"
                     /locus_tag="ACHY1N_003480"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004106 - chorismate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0004665 - prephenate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0006571 - tyrosine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HFS4045715.1"
                     /translation="MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLTLSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIG
                     KLPPLPKDCILVDLASVKNGPLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGR
                     KPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQG
                     DKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ"
     gene            complement(9013..10083)
                     /gene="aroF"
                     /locus_tag="ACHY1N_003481"
     CDS             complement(9013..10083)
                     /gene="aroF"
                     /locus_tag="ACHY1N_003481"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HFS4045716.1"
                     /translation="MQKDALNNVHITDEQVLMTPEQLKAAFPLSLQQEAQIADSRKTI
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPDGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHQDLNGLLTARVA"
     gene            10293..10658
                     /gene="yfiL"
                     /locus_tag="ACHY1N_003482"
     CDS             10293..10658
                     /gene="yfiL"
                     /locus_tag="ACHY1N_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2799 domain-containing protein"
                     /protein_id="HFS4045717.1"
                     /translation="MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISG
                     SAIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQ
                     LHEVWQKGADENASTIRLN"
     gene            10808..11326
                     /gene="yfiR"
                     /locus_tag="ACHY1N_003483"
     CDS             10808..11326
                     /gene="yfiR"
                     /locus_tag="ACHY1N_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HFS4045718.1"
                     /translation="MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTR
                     WPALSGPPKLCIFSSSRFSTALQENAATSLPYLPVIIHTQQEAMISGCNGFYFGNESP
                     TFQMELTEQYPSKALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNP
                     DVLMLARKKNDG"
     gene            11316..12542
                     /gene="dgcN"
                     /locus_tag="ACHY1N_003484"
     CDS             11316..12542
                     /gene="dgcN"
                     /locus_tag="ACHY1N_003484"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HFS4045719.1"
                     /translation="MMDNDNSLNKRPTFKRALRNISMTSIFITMMLIWLLLSVTSVLT
                     LKQYAQKNLALTAATMTYSLEAAVVFADGPAATETLAALGQQGQFSTAEVRDKQQNIL
                     ASWHYTRKDPGDTFSNFISHWLFPAPIIQPIRHNGETIGEVRLTARDSSISHFIWFSL
                     AVLTGCILLASGIAITLTRHLHNGLVEALKNITDVVHDVRSNRNFSRRVSEERIAEFH
                     RFALDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDA
                     RKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLRHKAYRLGGDEFAMV
                     LYDVQSESEVQQICSALTQIFNLPFDLHNGHQTTMTLSIGYAMTIEHASAEKLQELAD
                     HNMYQAKHQRAEKLVR"
     gene            12558..13040
                     /gene="yfiB"
                     /locus_tag="ACHY1N_003485"
     CDS             12558..13040
                     /gene="yfiB"
                     /locus_tag="ACHY1N_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HFS4045720.1"
                     /translation="MIKHLVAPLIFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAG
                     DWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNE
                     GLSLKRANVVADAWAMGGQIPRSNLTTQGLGKKYPIASNKTAQGRAENRRVAVVITTP
                     "
     gene            complement(13117..13464)
                     /gene="rplS"
                     /locus_tag="ACHY1N_003486"
     CDS             complement(13117..13464)
                     /gene="rplS"
                     /locus_tag="ACHY1N_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFS4045721.1"
                     /translation="MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(13506..14273)
                     /gene="trmD"
                     /locus_tag="ACHY1N_003487"
     CDS             complement(13506..14273)
                     /gene="trmD"
                     /locus_tag="ACHY1N_003487"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFS4045722.1"
                     /translation="MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVL
                     GHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            complement(14304..14852)
                     /gene="rimM"
                     /locus_tag="ACHY1N_003488"
     CDS             complement(14304..14852)
                     /gene="rimM"
                     /locus_tag="ACHY1N_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFS4045723.1"
                     /translation="MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLE
                     EGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLTTRSIEVDWDPGF"
     gene            complement(14871..15119)
                     /gene="rpsP"
                     /locus_tag="ACHY1N_003489"
     CDS             complement(14871..15119)
                     /gene="rpsP"
                     /locus_tag="ACHY1N_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFS4045724.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA"
     gene            complement(15256..16617)
                     /gene="ffh"
                     /locus_tag="ACHY1N_003490"
     CDS             complement(15256..16617)
                     /gene="ffh"
                     /locus_tag="ACHY1N_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFS4045725.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDF
                     LEQLRQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTMKERAKPE
                     IIKGSRKRRIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            16784..17575
                     /gene="ypjD"
                     /locus_tag="ACHY1N_003491"
     CDS             16784..17575
                     /gene="ypjD"
                     /locus_tag="ACHY1N_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417102.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HFS4045726.1"
                     /translation="MPVFALLALVAYSVSLALIVPGLLQKNGGWRRMAIISAVIALVC
                     HAIALEARILPDGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALI
                     NLALATFMPNEYITHLEATPGMLVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKKL
                     AFNQEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSMENIDKAVLSIVAWF
                     VYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLAYFGSRIVQQLIS"
     gene            17596..18882
                     /gene="yfjD"
                     /locus_tag="ACHY1N_003492"
     CDS             17596..18882
                     /gene="yfjD"
                     /locus_tag="ACHY1N_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HFS4045727.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVPRSEIIGID
                     INDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKETMLRAA
                     DEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE"
     gene            19005..19610
                     /locus_tag="ACHY1N_003493"
     CDS             19005..19610
                     /locus_tag="ACHY1N_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HFS4045728.1"
                     /translation="MSEDYVIEWDKDFADDLNVVASVFLQHTPTLWPTIFSQLSTQPE
                     IFEDEDEDEYGLQDVLDCSGGDLGNRDLAQAFLQVLRGEGLIQLVDWKGEDEEGELAN
                     FAADRFYELTKNLIASEELRSLLVEITQEDEISDVCEAGDRYLDEIFERIQTELNKRG
                     FQIFDLNEGSDTYNVVVLPMNEYKKIDDFNTPWLEVQDFLS"
     gene            complement(19645..20235)
                     /gene="grpE"
                     /locus_tag="ACHY1N_003494"
     CDS             complement(19645..20235)
                     /gene="grpE"
                     /locus_tag="ACHY1N_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFS4045729.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKI
                     ANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSL
                     DRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAK"
     gene            20358..21236
                     /gene="nadK"
                     /locus_tag="ACHY1N_003495"
     CDS             20358..21236
                     /gene="nadK"
                     /locus_tag="ACHY1N_003495"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HFS4045730.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIA
                     HELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLT
                     DLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS
                     YFNTLSTKLGWSKKLF"
     gene            21322..22983
                     /gene="recN"
                     /locus_tag="ACHY1N_003496"
     CDS             21322..22983
                     /gene="recN"
                     /locus_tag="ACHY1N_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFS4045731.1"
                     /translation="MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGL
                     CLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMT
                     ARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLA
                     NSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQ
                     IAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQ
                     QLDDQADSQETLALAVTKHHQQALEIARALHQQRQQYAEELAQLITDSMHALSMPHGQ
                     FTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKE
                     TDGAMTETHMQSLNKKARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            23132..23473
                     /gene="bamE"
                     /locus_tag="ACHY1N_003497"
     CDS             23132..23473
                     /gene="bamE"
                     /locus_tag="ACHY1N_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417107.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HFS4045732.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVS
                     KIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQPGHEGVTQQTLTLTFNSSGVLT
                     NIDNKPALSGN"
     gene            complement(23535..23825)
                     /gene="yfjF"
                     /locus_tag="ACHY1N_003498"
     CDS             complement(23535..23825)
                     /gene="yfjF"
                     /locus_tag="ACHY1N_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HFS4045733.1"
                     /translation="MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRT
                     DIDLTKNKVGIYSRPAKLSDSVHDGDRVEIYRPLIADPKELRRQRAEKSANK"
     gene            complement(23815..24252)
                     /gene="ratA"
                     /locus_tag="ACHY1N_003499"
     CDS             complement(23815..24252)
                     /gene="ratA"
                     /locus_tag="ACHY1N_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010376629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin RatA"
                     /protein_id="HFS4045734.1"
                     /translation="MPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCTGSRILESTP
                     GQMTAAVDVSKAGISKTFTTRNQLTSNQSILMNLVDGPFKKLIGGWKFTPLSQEACRI
                     EFHLDFEFTNKLIELAFGRVFKELASNMVQAFTVRAKEVYSAR"
     gene            24423..24905
                     /gene="smpB"
                     /locus_tag="ACHY1N_003500"
     CDS             24423..24905
                     /gene="smpB"
                     /locus_tag="ACHY1N_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFS4045735.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSL
                     RAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
                     "
     gene            25120..25482
                     /gene="ssrA"
                     /locus_tag="ACHY1N_003501"
     tmRNA           25120..25482
                     /gene="ssrA"
                     /locus_tag="ACHY1N_003501"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            25717..26925
                     /locus_tag="ACHY1N_003502"
     CDS             25717..26925
                     /locus_tag="ACHY1N_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HFS4045736.1"
                     /translation="MSVFHNWLLDIASGNYFIYIKRLSANDTGATGGHQVGLYIPSNI
                     VEKLFPSINHTRELNPSVFLTAHVSSHDCPDTQARAIYYNNRYFGKTRNEKRITRWGR
                     GSPLQNPENTGALTILAFRLNEQNTDCSEVDIWVCVNPDEEDIIESAIGEIIPGTLIS
                     GPAGQILGGLSLQQTPVNHKYVIPEDWKKRFPSGNEIIQYAAGHYAKNSKDPDEQLID
                     RRRVEYDIFLLVEELHVIDIIKKGFDSVDEFIALANSVSNRRKSRAGKSLELHLEKLF
                     IEHGLRHFSTQAVTEGNKKPDFLFPSAEAYHNVEFPVENLRMLAVKTTCKDRWRQILN
                     EADKIHQVHLFTLQEGVSSAQYREMKDAGVRLVVPSTLHKKYPEAVREELITLGAFIT
                     ELIELYAELS"
     gene            complement(26960..28393)
                     /locus_tag="ACHY1N_003503"
     CDS             complement(26960..28393)
                     /locus_tag="ACHY1N_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFS4045737.1"
                     /translation="MSEFEVLAQHLLKEAEAEEKLRQENDKKLIEKVLEIYDQKYVAE
                     LLRKVGKNEWSRETINRWINGKCLPKSLTSVEESLLRKMLPEPPANHPEYAFRFIDLF
                     AGIGGIRKGFEAIGGQCVFTSEWNKDAVRTYKANWFNDEQVHKFNLDIREVTLSDKTD
                     VLETDAYAYIDEHVPDHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFECEAQGTLFFDV
                     ARIIRAKKPAIFVLENVKNLKSHDKGKTFKVIMETLDELGYEVADAAEMGKNDPKIID
                     GKHFLPQHRERIVLVGFRRDLNIHKGFTLRDISRFYPEHRPSFGELLEPVVDSKYILT
                     PKLWEYLYNYAKKHAAKGNGFGFGLVNPENKESIARTLSARYHKDGSEILIDRGWDMA
                     TGEADFMNESNQARRPRRLTPRECARLMGFEKPGGKPFRIPVSDTQSYRQFGNSVVVP
                     VFEAVARLLEPYILKAVSADAGKTGQP"
     gene            28800..29573
                     /locus_tag="ACHY1N_003504"
     CDS             28800..29573
                     /locus_tag="ACHY1N_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045738.1"
                     /translation="MDITEFPSGVIEHLGWYVYRLIDPRDGSTFYVGKGKGNRVFAHM
                     RGEVAATDDDELLSNKLKQIREIRLAGLEVIHVIHRHGMTDEKTAYEVEAALIDAYPG
                     LTNIMNGAGSNEFGAAHVKELIATYQPETIIFHHKALMISVNRSAKDSELYDAVRFSW
                     RINVSRASQAEVILATVRGIVRGVFIADKWLKSTRENFPTMKYWDEDPDFEATQSSRY
                     GFEGREAPPEIANLYLGKKIPDELRKKGAMSPVRYSPNF"
     gene            complement(29631..30185)
                     /gene="pinE"
                     /locus_tag="ACHY1N_003505"
     CDS             complement(29631..30185)
                     /gene="pinE"
                     /locus_tag="ACHY1N_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA recombinase"
                     /protein_id="HFS4045739.1"
                     /translation="MLIGYVRVSTNDQNTDLQRNALNCAGCELIFEDKISGTKSERPG
                     LKKLLRTLSEGDTLVVWKLDRLGRSMRHLVILVEELRERGVNFRSLTDAIDTSTPMGR
                     FFFHVMGALAEMERELIVERTKAGLEAARAQGRIGGRRPKLTPEQWAQAGRLIASGVP
                     RQKVAIIYDVGISTLYKKFSVGDK"
     gene            30212..30613
                     /locus_tag="ACHY1N_003506"
     CDS             30212..30613
                     /locus_tag="ACHY1N_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001766570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4045740.1"
                     /translation="MMPFARYFCIFINVGLGEAAKRDVGTGENQIPDMSAWKRNPSSN
                     RWRKLPDGTIIQMGISASGPLGSPVNITLPISFSNTNYCVVASYDNARSGVSTMVSFA
                     ALPVSPSQFSLMSSVTEQGINPFAYWIAFGD"
     gene            30617..>30948
                     /locus_tag="ACHY1N_003507"
     CDS             30617..>30948
                     /locus_tag="ACHY1N_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HFS4045741.1"
                     /translation="MDRYFYSQKENGFFTDLNKAPSDAVEITTDEWLSLLDGQDNGMK
                     IVSNQEGYPVLTEQPPLSKENLIALAELKKGKLINEANEHMNSRQWPGKAAIGRLKGE
                     ELAQYNLWL"
BASE COUNT         8081 a         7923 c         7116 g         7828 t
ORIGIN      
        1 cagcaagctg tttcctgtta ccgttcgact tgcatgtgtt aggcctgccg ccagcattca
       61 atctgagcca tgatcaaact cttcaattta aaagtttgat gctcaaagaa ttaaacttcg
      121 taatgaatta cgtgttcact cttgagactt ggtattcatt tttcgtcttg cgacgttaag
      181 aatccgtatc ttcgagtgcc cacacagatt gtctgataaa ttgttaaaga gcagtgccgc
      241 ttcgcttttt ctcagcggcg cggggtgtgc ataatacgct ttcccgctac agagtcaagc
      301 atttattttt gctttctctg ccggaattct caggagaacc ccgctgaccc ggcggcgtgt
      361 ttgccgttgt tccgtgtcag tggtggcgca ttatagggag ttattccggc ctgacaagcg
      421 aaaaatataa aaactttatc gttcgctcat ttttcaggca aaacatctta aatatagtct
      481 tttccgtcta acttatagac aaaaacgagc cccgaagggc tcgttttatc atttactgga
      541 cggcgacaat ccggtcttca ttaacttcca ggcgaatcac tttacccgga accaattcac
      601 cagacagtat ttgctgtgcc agcgggtttt cgatctgctg ctggatagca cgtttcaaag
      661 gacgtgcacc atagactgga tcgtaaccgt tctcgctcag cagtttcagc gcctcgtcag
      721 aaatgtggat ttcataacca cgttcttcca gacgtttgta cagacgtttc aactgaatct
      781 gcgcaatcga ggcaatgtgc tgttcaccca gcggatggaa gaccaccact tcatcaatac
      841 ggttaatgaa ttccggacgg aagttatggc ttaccacacc gagcaccagc tctttcatgt
      901 gcgcataatc cagttcaccg aagcgttcct gaatcaaatc ggaaccgagg ttagaggtca
      961 taatgacaac cgtattacgg aagtcgaccg ttctcccctg cccgtcagtc agacgaccat
     1021 catccagtac ctgcaacaga atgttgaaga catccggatg cgctttttcc acttcatcca
     1081 gcaggatgac ggaatacgga cgacgacgca cagcttcggt caggtagcca ccttcttcat
     1141 aaccgacata tcccggaggc gcaccaacca gacgagacac cgagtgtttc tccataaact
     1201 cggacatatc gatacggacc atcgcctcgt cgctatcaaa cataaagttc gccagcgcct
     1261 tacaaagctc agttttcccc acacccgttg ggccgaggaa caggaatgaa ccaatcgggc
     1321 gatttggatc cgccaacccc gcacggctac ggcgaatagc gttagatacc gcatcaaccg
     1381 cttcgttctg accaatgacg cgatggtgca gttcttgctc catacgcagc agtttttcgc
     1441 gctcgctttc catcatgcga gaaaccggaa tccccgtcca acgcgccagc acttcagcaa
     1501 tttcggcgtc ggtcacttta ttacgcaaca gacgcatagt tttgccttcg agctgcgttg
     1561 cggcttccag ttgcttttcc agttccggga ttttgccgta ttgcagttca gacatccgcg
     1621 ccaggtcccc cacacggcga gcctgttcaa tagcgatttt cgcctgttcc agttccgctt
     1681 taatggtctg cgtaccagaa agcgatgcct tctctgcttt ccactcttct tctaactcgg
     1741 agtactgacg ttctttgtcg ctcagttctt cgttgagcat atccaggcgt tttttactgg
     1801 cttcatcaga ctctttcatt aacgcctgtt gttccagttt gagctggatg atacgacgat
     1861 cgagtcggtc gagttcttct ggttttgagt caatctgcat acgaatgctg gatgctgctt
     1921 catcgatcag gtcgatggct ttatccggca gctgacggtc agcaatgtag cgatgagaca
     1981 acgtcgccgc tgcaacaatt gccgggtcag taatttgcac atggtggtgc aattcgtaac
     2041 gttctttcag gccacgcaga atcgcaatgg tatcttcaac agaaggctcg gcaacaaaca
     2101 ctttctggaa acgacgttcc agcgcagcat ctttttcgat gtactggcga tattcgtcaa
     2161 gcgtcgtggc acctacgcag tgcaattcac cacgcgccag cgccggtttc agcatgtttc
     2221 cggcgtccat tgcgccatcg gctttacccg cgccgaccat ggtatgtaat tcgtcgataa
     2281 acaggatgac gttgccttcc tgtttggcaa gatcgttaag cacgcctttt aaacgttctt
     2341 caaactcacc gcgatatttc gccccagcca ccagcgcgcc catatccagc gccagtacgc
     2401 ggcggccttt caatccttcc ggcacttcgc cgttgataat acgctgcgcc agaccttcaa
     2461 cgatggcagt tttaccgacg ccgggttcac caatcagtac cgggttattt ttagtacgac
     2521 gttgcagcac ctgaatggta cggcgaattt cttcatcacg accaatcacc ggatcgagtt
     2581 tgccctgttc ggctcgttcg gtaaggtcga tggtatattt tttcaaagcc tgacgttggt
     2641 cttcagcacc ttgatcgttc acgctttcac ctccacgcat ttgttcaatc gcttgagtaa
     2701 tgttggcggt ggtcgcccct gctgctttca ggatgtcggc cagcgtgccg cgagactcaa
     2761 gtgccgccag aacgaacagt tctgacgaga taaagttatc accacgtttt tgcgccagct
     2821 tgtcgcaaag attaagaacg cgcaccagat cctgtgatgg ctggacatca ccaccagtac
     2881 cttcaacctg cggtaaacga tttaatgcct gattgatatc tgtgcgcaac tggccagcat
     2941 ttatgccagc ggatgttaat aaaggactaa ccgaaccccc ttcctgattc agcagggcgc
     3001 tcattaaatg aagtggttcg ataaattggt tgtcgtgccc gagtgcaagt gattgggcat
     3061 cggcaagagc aagctggaat ttattagtaa gacgatccag acgcataact cctcccataa
     3121 cggatcaaag ttgctactgg agattaaatg aggtcatccc tcaattattc aaggttattg
     3181 accagattaa tgtgaaaaga aaatcacgcg taccggatcg tcttgattct ttaggttata
     3241 tcagccaaat gaaacttgcc atacgaccgg tggtcttgtc gcgacgataa gagaagaaag
     3301 tctcattttc cgtatatgta caacggtcgc cgccgaaaat ttgctcaaca cccacgttcg
     3361 ccagacgctg ccgggcaagc tgataaatat ccgccagata cttatcacca tgctgaatga
     3421 aagctgcact tgctttagcg tctactgcca taaacgcctc gcgaacctcc acccccactt
     3481 cgaacgcgcg tggaccaatt gccggcccta accaggcgag aatattttcc ggattatcag
     3541 caaaacagga aaccgtctct tccagcacgc ctgcgcacag tccacgccag ccagcatgag
     3601 cggcggcgac ttccgttccc gctcgattgc aaaacagcac agggaggcag tcggcagtca
     3661 tcactgcgca aaccgtgccg ggcgtattgc tataagaggc atctgctcgt tttgaggcat
     3721 aagcttcgcc agtaagctta agcacatctt tgccgtgtac ctgctcaagc cagaccggtt
     3781 tagaaggcaa attgcccgca gcaaaaagtc gcttgcgatt ctcctcaacg tgatccgggt
     3841 tatcgccaca atgggcaccg aggttgagcg agtcatacgg gggcaaactc acgccgccga
     3901 tacgagaaga gctacaggcc gcaacacctt ttggtagcgg ccactgcggg acaatcagct
     3961 tactcataac cagtccactt catccttatg ctcttcgaaa tcggcgcgca tcacctcaat
     4021 cagctccacc atatcttgtg gaataggcgc atgccattcc atttcgatgc cggagatcgg
     4081 gtgataaaga cgcagcatgg ttgcatgaag cgcctggcgg tcaaacttac gcagcatgga
     4141 gataaatgct tccgaagcac cttttggcgg acgcggacgg ccaccataaa ccggatcgcc
     4201 caccagcgga tgagtgatat gggccatatg cacgcggatc tggtgcgtac gtccagtttc
     4261 cagacgcaac cgcagacgcg tgtgcacacg gaagtgttcc atgatgcgat agtgagtcac
     4321 cgccggtttg cccatcggat gcaccgccat gtgagtacgt ttggtcgggt ggcggctgat
     4381 gggttcatct actgtaccgc cagcggtcat atgaccaatc gccaccgctt catactcacg
     4441 agtaatttca cgccgttgca aagattcgac taaacgcgtc tgagccggaa cggtttttgc
     4501 cacaaccatc aggccagtgg tgtctttatc cagacgatgg acgatgcccg cacgtggtac
     4561 atcggcaatg ggcggatagt aatgaagcaa cgcattcagt accgtgccat ccgggttacc
     4621 cgcgccagga tgtaccacca ggtcgcgcgg tttattaatg acgatgatat cttcatcttc
     4681 atagacgata tccagcggga tatcctgcgg ttcaaaacgc gcttcttctt caatctcagc
     4741 gttgatggca acctgctcgc cacccaatac tttttctttc ggcttatcac aaactttgcc
     4801 gtttaccagc acgcgctggt cgaggatcca ttcttttatt cgcgaacgtg aataatccgg
     4861 gaacatttcg gccaaagcct gatctaagcg ttgaccgagt tggttttcgg acaccgttgc
     4921 agtgagctgt actcgttgtg ccatatatac tgcttcttcg tttatcgttg gggttttacg
     4981 gctttgccgt ttaatatagt gtgctattgt agctggtctt aaccgggagc aggaacagag
     5041 aatctcccgt attacatttt gaggaaagtc aaaacgtcat gacgcgcatg aaatatctgg
     5101 tggcagccgc cacactaagc ctgtttttgg cgggttgctc ggggtcaaag gaagaagtac
     5161 ctgataatcc gccaaatgaa atttacgcga ctgcacaaca aaagctgcag gacggtaact
     5221 ggagacaggc aataacgcaa ctggaagcgt tagataatcg ctatccgttt ggtccgtatt
     5281 cgcagcaggt gcagctggat ctcatctacg cctactataa aaacgccgat ttgccgttag
     5341 cgcaggctgc catcgatcgt tttattcgcc ttaacccgac ccatccgaat atcgattatg
     5401 tcatgtacat gcgtggcctg accaatatgg cgctggatga cagtgcgctg caagggttct
     5461 ttggcgttga ccgtagcgat cgcgatcctc aacatgcacg agctgcgttt agtgactttt
     5521 ccaaactggt gcgcggctat ccaaacagtc agtacaccac cgatgccacc aaacgtctgg
     5581 tattcctgaa agatcgtctg gcgaaatatg aatactccgt ggccgagtac tatacagaac
     5641 gtggcgcatg ggttgccgtc gttaaccgcg tagaaggaat gttgcgcgac tacccggata
     5701 cccaggctac gcgtgatgcg ctgccgctga tggaaaatgc ataccgtcag atgcagatga
     5761 atgcgcaagc tgaaaaagta gcgaaaatca tcgccgcaaa cagcagcaat acataacaga
     5821 aacctgaaat acaaaacggc agcccttgag ctgccgtttt tttattctgt tagttgtgaa
     5881 actgaagcga tttagtcact atcgatctca tcaaatatgg ctcgctttga gatattcctc
     5941 aagtaaaaaa acacctcttc ctgcgatttc tcacaaaaaa gattcgttga caaaaagtga
     6001 caaaattatg agattcccat cacacatttt gacatcagga gcggtatgct gaattcacca
     6061 agacgggaag acaagaggta aaatttatga caatgaacat taccagcaaa caaatggaaa
     6121 ttactccggc catccgccaa catgtcgcag accgtctcgc caaactggaa aaatggcaaa
     6181 cacatctgat taatccacat atcattctgt ccaaagagcc acaagggttt gttgctgacg
     6241 ccacaatcaa tacacctaac ggcgttctgg ttgccagtgg taaacatgaa gatatgtaca
     6301 ctgcaattaa cgaattgatc aacaagctgg aacggcagct caataaactg cagcacaaag
     6361 gcgaagcacg tcgtgccgca acatcggtga aagacgccaa cttcgtcgaa gaagttgaag
     6421 aagagtagtc ctttatattg agtgtatcgc caacgcgcct tcgggcgcgt tttttgttga
     6481 cagcgtgaaa acagtacggg tactgtacta aagtcactta aggaaacaaa catgaaacac
     6541 acaccgtttt tcttcgcatt cttttttacc ttcccctgaa tgggaggcgt ttcgtcgtgt
     6601 gaaacagaat gcgaagacga acaataaggc ctcccaaatc ggggggcctt ttttattgat
     6661 aacaaaaagg caacactatg acatcggaaa acccgttact ggcgctgcga gagaaaatca
     6721 gcgcgctgga tgaaaaatta ttagcattac tggcagagcg gcgcgaattg gccgtcgagg
     6781 taggaaaagc caaactgctc tcgcatcgcc cggtacgaga tattgatcgt gaacgcgatt
     6841 tactggaaag attaattacg ctcggtaaag cgcaccatct ggacgcccat tacattactc
     6901 gcctgttcca gctcatcatt gaagattccg tattaactca gcaggctttg ctccagcaac
     6961 atctcaataa aattaatccg cactcagcac gcatcgcttt tctcggcccc aaaggttctt
     7021 attcccatct tgcggcgcgc cagtatgctg cccgtcactt tgagcaattc attgaaagtg
     7081 gctgcgccaa atttgccgat atttttaatc aggtggaaac cggccaggcc gactatgccg
     7141 tcgtaccgat tgaaaatacc agctccggtg ccataaacga cgtttacgat ctgctgcaac
     7201 ataccagctt gtcgattgtt ggcgagatga cgttaactat cgaccattgt ttgttggtct
     7261 ccggcacgac tgatttatcc accattaata cggtctacag ccatccgcag ccattccagc
     7321 aatgcagcaa attccttaat cgttatcctc actggaagat tgaatatacc gaaagtacgt
     7381 ctgcggcaat ggaaaaggtt gcacaggcaa aatcaccgca tgttgctgca ttgggaagcg
     7441 aagctggcgg cactttgtac ggtttgcagg tactggagcg tattgaagcg aatcagcaac
     7501 aaaacttcac ccgatttgtg gtgttggcac gtaaagccat taacgtgtct gaccaggttc
     7561 cggcgaaaac gacgttgtta atggcgaccg ggcaacaagc cggtgcgctg gttgaagcgt
     7621 tgctggtgct gcgcaaccac aatctgatta tgacccgtct ggaatcacgc ccgattcacg
     7681 gtaatccatg ggaagagatg ttttatctgg atattcaggc caatcttaaa tcagcggaaa
     7741 tgcaaaaagc attgaaagag ttaggggaaa ttacccgttc aatgaaggta ttgggctgtt
     7801 acccaagtga gaacgtagtg cctgttgatc caacctgatg aaaaggtgcc ggatgatgtg
     7861 aatcatccgg cactggatta ttactggcgg ttgtcattcg cctgacgcaa taacacgcgg
     7921 ctttcactct gaaaacgctg tgcgtaatcg ccgaaccagt gctccacctt gcggaaactg
     7981 tcaataaacg cctgcttatc gccctgctcc agcaactcaa tcgcctcgcc gaaacgctta
     8041 tagtaacgtt tgattaacgc cagattacgc tctgacgaca taataatgtc ggcataaagc
     8101 tgcggatcct gagcaaacag tcgcccgacc atcgccagct caaggcggta aatcggcgaa
     8161 gagagcgcca gaagttgctc aagctgaaca ttttcttctg ccagatgcag cccataagca
     8221 aaagtagcaa agtggcgcag agcctgaata aacgccatat tctgatcgtg ctcgacagcg
     8281 ctaatacgat gcagccgagc gccccagacc tgaatttgct ccagaaacca ttggtatgct
     8341 tccggcttac gtccatcaca ccagaccaca acttgctttg ccaggctacc gctgtccggg
     8401 ccgaacatcg ggtgtaaccc cagtaccggg ccatcgtgcg ccgccagcat ggcctgtaat
     8461 ggtccatttt tcactgatgc cagatcaacc agaatacaat ctttcggtaa aggcggtaat
     8521 ttgccgataa cttgctcagt aacgtggatt ggcacactaa caatcaccat tccggcatcg
     8581 gcaacaatat cagccgctcg atcccagtca tgttgctcca gaatccgcac ctgataaccc
     8641 gagagggtca gcatcttctc gaacaggcgt cccatctgac cgccaccgcc gacgataacc
     8701 accggacgca gtgacggaca aagtgtttta aatcctttgt cgttttcact ggagtaagat
     8761 tcacgcatca cccgacgcaa aacatcctca atcagatctg gcggtacacc cagagcttcc
     8821 gcctctgcac gacgcgaggc caacatagat gcctcgcgct ccggaacata aataggcagt
     8881 ccaaagcggc ttttcacctc gcccacttca gcaaccagtt ccagacgctt agctaataaa
     8941 ttcagcagcg ctttatcgac ttcatcaatt tgatcgcgta atgcggtcaa ttcagcaacc
     9001 ataataaacc tcttaagcca cgcgagccgt cagcagcccg ttcagatcct gatgaatttc
     9061 acgcagcaag gcatcggtca tttcccagct aatgcaggca tcggttacgg atacaccgta
     9121 tttcatttca ctgcgcggtt gctcggaaga ctgattgccc tcgtggatat tactttcgat
     9181 catcagacca ataattgagc gattgccatc tttgatttga gcaaccacgg attctgccac
     9241 cgcaggctga cggcgataat ctttattgga attaccgtgg ctgcaatcta ccatcagaga
     9301 cgggcgcagt cccgcctgtt ccatctcttt ttcacattgc gcaacatccg cagggctata
     9361 gttcggcgct ttaccaccgc gcaggatgac atgcccgtcc ggattcccct gagtttgtag
     9421 caacgcaacc tgccctgcct ggttaatgcc aacaaaacgg tgcggctggg cggcggcgcg
     9481 catagcgtta attgctgttg ccagactgcc gtcggtgccg tttttaaaac caaccggcat
     9541 ggaaagcccg gaggccattt cacggtgagt ttgcgattcc gttgtacgag caccaattgc
     9601 tgaccagcta aacagatcgc ccaggtattg cgggctattc ggatctaacg cttccgtcgc
     9661 cagtggcagt cccatattca ccagctcaag cagcaattta cgcgcgatct gcagcccggc
     9721 ttctacatca aaagagccat ccatatgggg atcgttaatt aaccctttcc agccgacagt
     9781 ggtacggggt ttttcaaaat agacgcgcat taccagatag aggctatcgc tgacctctgc
     9841 ggcaagggct ttaaatcgac gagcatattc cagagcagtt tccggatcat gaatggaaca
     9901 aggaccacat actaccagca gacgaggatc gcgcccggcg ataatatctg aaatggtttt
     9961 acgcgagtca gcaatctggg cttcttgttg caggctcaat ggaaaagcgg ccttcagttg
    10021 ttccggagtc attaaaacct gttcgtcggt aatatgtacg ttattcagcg cgtctttttg
    10081 catgatggcg atcctgttta tgctcgtttg cgatagttga tcctcagcga ggatgacgta
    10141 acgataacac ataaagtaaa gttttcaatc catatttcgt acatttttat ttacacaggc
    10201 aatttagtcg cgatttcaac ccttacttct gtatagataa atttacactt cctttgaaaa
    10261 caatccgcta tgctttgaaa aaggagaaag aaatgatgaa aaagtttatc gcccccttgt
    10321 tggctttact ggttagcgga tgtcagattg atccttatac tcacgcgcca accttgacca
    10381 gcaccgactg gtatgatgtt ggtatggaag atgcgatatc gggcagcgcc ataaaagatg
    10441 acgatgcatt tagcgattca caggcggatc gcggtctata ccttaaagga tatgccgaag
    10501 gacaaaagaa aacttgccag accgatttta cttatgcccg gggactttcc ggtaaaagct
    10561 ttcctgccag ctgcaacaat gttgaaaatg ccagccaact gcatgaagta tggcaaaaag
    10621 gggctgatga aaatgccagc acaatacgat taaattaatt aaaaccccac aaataaatta
    10681 aacataagat tttactcatt gtgttttatt tctcacattg atgacgatcg catgaaaaaa
    10741 tgatatttta atgagcattc tgaaaaaata tcgatgcatt tcgagcgaag atggtgggga
    10801 tccctgaatg cgtttttctc accgactgtt cttacttctg attctcctgc tgacgggagc
    10861 accaatactc gctcaggagc cttctgacgt tgcgaaaaac gtgcgtatga tggtttccgg
    10921 tattgtcagt tacacccgct ggcctgcgct atcagggcca ccaaagttat gtatcttttc
    10981 atcttcacgt tttagtaccg ccctacaaga gaatgccgcg acatctttgc cttatctgcc
    11041 tgtcatcatt cacactcaac aagaggcgat gatttcaggc tgcaatggtt tttattttgg
    11101 caacgagtca ccgacattcc agatggaatt aaccgaacaa tatccgtcaa aggcgttatt
    11161 attaattgcc gaacaaaata ccgagtgcat tattggtagc gccttttgtc tgatcatcca
    11221 caataatgac gtcagatttg ccgtaaacct ggatgcctta tcgcgtagcg gtgtaaaggt
    11281 caacccggat gtcttaatgc tcgcacggaa gaaaaatgat ggataacgat aattctctta
    11341 ataagcgccc cacgtttaaa agagcattac gcaacatcag tatgaccagc atatttatca
    11401 ctatgatgct gatctggttg ctgctttccg tgacctcggt gctgaccctg aaacagtacg
    11461 cgcaaaaaaa cctggcactg acagcagcaa caatgactta cagtctggaa gcagctgtcg
    11521 tttttgccga tggccctgca gcaactgaaa cactggcagc gctgggccag caagggcaat
    11581 tttcaactgc agaagtacgt gataagcagc aaaatattct ggcgtcctgg cattacaccc
    11641 gtaaggatcc aggcgatact ttcagcaatt tcataagcca ctggctcttc cccgccccca
    11701 tcattcagcc gattcgtcac aatggtgaaa ccattggcga agtacgctta accgctcgcg
    11761 acagttcaat cagccatttt atctggtttt cgctcgccgt actgaccggt tgtattctgc
    11821 tggcatcagg catcgcaatt accctcaccc gccatttgca caatggcctg gtagaagcgc
    11881 tgaaaaatat caccgatgtc gtacatgatg tgcgttccaa ccgcaatttt tcccgacgag
    11941 tttcggaaga acgtatcgct gagtttcacc gcttcgctct cgacttcaac agtctgctgg
    12001 atgaaatgga agagtggcag cttcgtttac aggccaaaaa tgcgcagctt ctgcgtaccg
    12061 cgctacatga cccattaacc gggctggcta accgcgcagc gtttcgtagc ggcatcaata
    12121 cgttgatgaa caattccgat gcccgaaaaa cgtcggcgtt actatttctt gatggcgata
    12181 atttcaaata tatcaatgat acctggggtc atgcgacggg cgatagagtc ttgattgaaa
    12241 tcgcaaaacg gttagctgaa tttggcgggc tgcgacataa agcataccgc ctgggcggcg
    12301 atgaattcgc tatggtgctc tatgatgtac agtcggaatc tgaagtgcag cagatatgct
    12361 cagcactgac acaaatcttt aatctccctt ttgatcttca taatggccat cagaccacca
    12421 tgacattaag cattggttac gcgatgacca ttgagcacgc ctctgcggaa aaattacaag
    12481 agcttgccga tcacaatatg tatcaggcca aacaccagcg tgccgaaaag ctggtgagat
    12541 aacaaggata tatcgatatg ataaagcacc tggtagcacc cctgattttc acctcactaa
    12601 tactgactgg ctgccagtcc cctcagggaa agtttactcc tgagcaagtc gccgctatgc
    12661 aatcttatgg atttactgaa tccgccggcg actggtcgct gggcttatca gatgccattc
    12721 tgttcgcaaa aaatgactac aaattgctcc cggaaagcca gcaacagatc caaaccatgg
    12781 cagccaaatt ggcctcgaca gggctaacac atgcccgtat ggatggacac accgataact
    12841 atggtgaaga cagttacaac gaaggcttat cattgaaacg ggcgaatgtc gtggccgatg
    12901 catgggctat gggtggacaa attccacgca gcaatctcac cacacagggt ttaggaaaaa
    12961 aatatcccat agccagtaac aagaccgccc agggccgcgc cgagaaccgc cgcgtcgcag
    13021 tggtgattac aaccccttaa aacacgagca aacagacaaa aaaagggcca gccaattggc
    13081 cagcccttct taacaggatg tcgcttaagc gaaatcttag ttaagacgct ctttgatacg
    13141 agcagcctta ccagtacgct cacgcaggta gtacagttta gctttacgaa cagcaccacg
    13201 acgtttgaca gaaatgctgt caactaccgg agagtgagtc tggaagacac gctcaacgcc
    13261 ttcgccgttg gaaattttac gaacagtgaa tgcagagtgc agaccgcggt tacgaatagc
    13321 gataaccacg ccctcgaatg cctgcagacg ttttttggaa ccttcaacaa cccatacttt
    13381 cacttccacg gtatcacccg gacggaagga aggtacgtcc tgcttcatct gctcttgttc
    13441 aagttgctta ataatgttgc tcataattta atctcttatc ctgggtaaac tgatatctcg
    13501 ggggcttacg ccatcccatc atgtttatgt tgctgttgtg cgtgttccgt tttgaactcc
    13561 gccagcaacc ttgcttgctc ttcagtcaga gccaggtttt ccagaagttc aggtcttcta
    13621 agccaggtac ggcccagcga ctgtttcaaa cgccagcgac gtatctcggc atggttgccc
    13681 gacagtaaca ctggcggaac ttccatccct tctaacacct caggccgcgt atagtgcggg
    13741 caatccagca atccttcagc aaaggaatct tccgttgccg aggcttcatg tcccagtact
    13801 cccggaataa accgggaaac ggagtcaatc agcgtcattg ctggtaactc accaccactg
    13861 agaacgtaat cgccgattga ccattcttcg tcaatttcgg tttggatcac gcgctcatct
    13921 ataccttcgt agcgaccgca caccagaatc aatttttgat tcgttgccag ttcgctgacg
    13981 cccgcttgat caagcttgcg tccctgtggt gacagataaa tcacctttgc gccttcaccc
    14041 gccgcggctt ttgctgcatg aatggcgtcc cgcaagggtt gcaccatcat taacatcccc
    14101 ggtccgccgc cgtaaggacg atcgtccacg gtacggtgcc ggtcatgcgt gaagtcgcga
    14161 ggactccaac tctggatgct cagcaggcca tttttaactg cccggccagt taccccgtaa
    14221 tcggtaattg cgcggaacat ttcaggaaac aggctaatta tgccaatcca catagcgccg
    14281 tcttttaccg tttatccggt ggtttaaaaa ccaggatccc aatctacttc gattgaacga
    14341 gtagtgagat cgactttctt gataacctgc ccatcgagga acggtacgag acgttccttg
    14401 ataccaaacg catctttcag gtttgcctta atgacgagaa cgtcattaga tccggtttcc
    14461 atcatatcga cgactttacc gagatcgtag ccttcagtgg ttactacctg gcagcccatc
    14521 aggtctttcc agtagtagtc accctcttca agctgaggca gctgcgatga atccacgaca
    14581 atttcacaat tcgtcagcag gttcgccgca tcacgatcgt caacgccttt cagcttgatg
    14641 atcatgtcct gattgtggtg cttccagctt tccagctgga cttgctgcca ctgacccgcc
    14701 ttctggataa accagggctg atagtcaaaa atgctttcgg cgtcttcggt ggaagaaaac
    14761 actctgagcc acccacgaat accgtaagac gaacccattt ttcccaaaac gatgggatca
    14821 acaggtgctt gcgcggtgag ttgtttgctc atcatgacca ccgtgacaga ttaagctgct
    14881 ttgtttactt ctttgatcag cgcagcaacg cgatcagaaa tagttgcgcc ctggccaacc
    14941 cagtgagcga tgcgatccag atccaggcga gtgccttctt ctttttcgct agcgattggg
    15001 ttgaagaaac caacgcgctc gatgaagcga ccgttgcgtg cattacggct gtcagcgaca
    15061 acaacctggt agaacggacg ctttttagcg ccgtgacgtg ctaaacgaat agttaccata
    15121 acatcctctt gtgtgaataa aacaaccgga ccccatcgag gaacggagtc cggtgtcata
    15181 ttaaaagccc gaaaatttta ctgatttctg gagaaaatgc aatcagcagt taataactct
    15241 gtcgcataag gtcatttagc gaccaggaaa tcccggcggc atcatcccct tcatgcttct
    15301 catcatcttc gccattccgc ctttcttcat tttcttcatc atgcgctgca tgtcgtcgaa
    15361 ctgcttcaga aggcggttca cgtcctgcac ctgcataccg caaccggcag cgatacgacg
    15421 cttacgcgaa cctttgatga tttctggctt agcgcgctct ttcatcgtca tcgagttgat
    15481 gatggcttcc atacgcacca gcactttatc gtccatctgc gacttaacat tatccgggat
    15541 ctgccccatg cccggcagct tgcccatcag gctagccatg ccgcccatat ttttcatctg
    15601 gcgcagttgc tcaagaaaat cgttgagatc gaagccgtcg ccttttttca gcttgctggc
    15661 taatttctct gcctgcgcgc ggtcaacttt gctttcgata tcttcgatca gcgacagtac
    15721 gtcgcccatg ccgagaatac gcgacgcgat gcggtccgga tggaacggct ccagcgcctc
    15781 agttttctcg ccaacaccga gaaacttgat cggtttgcca gtgatgtgac gaatagagag
    15841 cgccgcaccg ccgcgggcat cgccgtccac tttggtcaac actacgccgg taagcggtaa
    15901 cgcttcattg aatgcttttg ccgtattggc cgcatcctga ccggtcatgg cgtcaaccac
    15961 aaacagggtt tcaaccgggt taatcgacgc atggacttgt ttgatctcgt ccatcatcgc
    16021 ttcgtcaacg tgcagacgac cagcggtatc caccagcagc acgtcgtaga atttcagttt
    16081 ggcttctttc agcgccgcgt taacgatatc taccggcttc tgaccaacat cagaagggaa
    16141 gaaatcaacg cccacctgct ctgccagcgt ctcaagctgt ttgattgccg ccgggcgata
    16201 aacgtcggca gaaaccacca gcactttctt cttgtgcttc tcgcgcagga acttaccgag
    16261 tttaccaacg ctggttgttt taccggcacc ttgcaggccc gccatcagta cgaccgcagg
    16321 cggttgcgca gccaggttca gggtctggtt ctcttcgccc atcgccgcaa ccagttcgtt
    16381 acggactatt ttgacgaact cctgccccgg cgtcaggctc ttattaactt catgaccaac
    16441 cgctttctct tttacgcgat tgataaactc acgcactacc ggcagagcga cgtccgcctc
    16501 cagcagcgcc atgcgcactt cgcgcagcgt atcttttacg ttgtcttcag tgaggcgtcc
    16561 acggccactg atattgcgca gcgtgcgcga caaacgatcg gttaaattat caaacattgt
    16621 ctctcgcctg gggtggaaac ggttggccgc aatcgcgaca catcatcagt attttgccgc
    16681 agtataacat gaaggcgtct ttgttgttat gcaacggttg gagcagcgtt cacctgacgc
    16741 tatactgctt ctctttctta ttgctcaaac tgtcgacatt actatgcccg tttttgctct
    16801 gctcgcgctt gtcgcctact ccgtcagtct tgcgctgatt gttcccggtc tgctgcaaaa
    16861 aaacggcggc tggcggcgca tggctattat ttctgcggtc attgcgctgg tctgccacgc
    16921 aatcgctctg gaagcccgca tcctgcccga cggtgatagc ggacaaaacc tcagcctgct
    16981 gaacgttggt tcattggtca gtttgatgat ctgtacggta atgaccattg tggcttctcg
    17041 caatcgtggc tggttgctgc tacccattgt ctatgccttt gcgcttatca acctggcgct
    17101 ggcgaccttc atgcccaatg aatacatcac ccatctggaa gcaacgcctg ggatgctggt
    17161 gcacattggc ttatcgctct tttcctatgc cacgctaatt atcgccgccc tgtacgcgct
    17221 gcaactggcg tggattgatt accaactgaa gaacaagaag ctggcattta accaggaaat
    17281 gccgccattg atgagtatcg agcgtaaaat gttccacatc acgcagattg gcgtggtgct
    17341 gctaacgctc acgctttgca ctggcctgtt ctacatgcac aacctattta gcatggaaaa
    17401 tatcgacaag gctgtgctct ctatcgtggc gtggtttgtc tatattgtgc tgctgtgggg
    17461 acattaccat gaaggatggc gtggacgccg cgtcgtctgg tttaacgttg cgggcgcggt
    17521 aattctgaca ctggcctact tcggcagccg aattgtccag cagttaatca gctaaaccca
    17581 gaaaaggagt ttcccctgga acacatttct actactacgt tgatcattat tctgatcatc
    17641 atggtggtca tttcagccta tttttccggg tccgaaaccg gaatgatgac cctcaaccgc
    17701 tatcgtctgc gacatatggc gaaacagggt aatcgctcgg ccaaacgcgt cgaaaaattg
    17761 ctgcgtaagc cagaccgcct gataagcctg gtgttaatcg gcaataacct ggtcaatatt
    17821 cttgcctccg cgctcggcac tattgttggg atgcgtttgt acggcgatgc gggcgtggca
    17881 attgcgactg gtgtgctgac ttttgtcgta ctggtatttg ctgaggtatt gccgaaaacc
    17941 attgccgcgc tgtacccgga aaaagtcgct tatccgagta gttttctgct ggctccgctg
    18001 caaattttga tgatgccgct ggtctggttg ctgaatgcta tcacccgtat gctgatgcgc
    18061 atgatgggta tcaaaaccga tatcgtggtt agcggctctt tgagcaaaga agagttgcgc
    18121 actatcgtgc acgaatcacg ctcacaaatt tcccgtcgca atcaggatat gctgctgtcg
    18181 gtgctcgatc tggaaaaaat gaccgttgat gacatcatgg tgccgcgcag tgaaattatc
    18241 ggtattgata tcaacgatga ctggaaatcg attctgcgcc aactctccca ctcacctcac
    18301 gggcgcatcg tgctctaccg tgattcgctg gacgacgcca tcagtatgct gcgagtacgt
    18361 gaagcctggc ggttgatgtc ggagaaaaaa gagttcacca aagaaaccat gctgcgcgcc
    18421 gcggacgaga tctattttgt gccggaaggt acgccgctca gcacgcagtt ggtaaagttt
    18481 cagcgcaaca aaaagaaagt cggcctggtc gtcaacgagt atggagacat tcaggggctg
    18541 gtgacggttg aagatattct ggaagagatt gtcggcgatt tcactacgtc gatgtcgcca
    18601 acacttgccg aagaggtcac gccgcaaaac gacggttcgg tgattatcga tggcaccgcc
    18661 aacgtgcggg aaatcaacaa agcctttaac tggcatctac cggaagatga tgcccgcacg
    18721 gttaatggcg tcattcttga ggcactggaa gagatccctg tcgcaggcac ccgcgtgcgt
    18781 attggcgagt acgatataga tattctcgac gtacaggaca atatgattaa gcaggtaaaa
    18841 gtttttcctg tgaaaccgct gcgcgagagt gtggcggagt aacgcaatgg cgaactccgg
    18901 ttcgcctttt ttttatcgcc gtcttttagg attccatcaa ttcctgtcat ttacttagca
    18961 atgtaataat gtcttttcaa gcattcggaa aggatattga tgttatgtca gaagattatg
    19021 taattgaatg ggataaggat tttgcagacg atctcaacgt cgtcgccagc gtttttttac
    19081 agcacacccc aaccttatgg cccactattt tctctcaact ttcgacgcaa cctgaaatct
    19141 ttgaagacga agatgaagac gaatatggat tgcaggacgt tctcgattgc agtggtggcg
    19201 atctcgggaa tcgtgacctg gcgcaggcat ttttacaggt tctacgcggt gaaggattaa
    19261 ttcaactcgt tgactggaaa ggtgaagatg aagaaggtga gctggctaat tttgctgcag
    19321 atcgctttta tgagctcaca aaaaacctga tagcttctga ggaattaagg agtcttcttg
    19381 tcgaaataac ccaagaggat gaaatctccg atgtctgtga agccggagac cgctaccttg
    19441 acgaaatctt tgaacgcatc caaaccgaac tcaataaaag gggctttcag atttttgatc
    19501 tgaatgaagg atctgacacc tataacgtgg tcgttctgcc aatgaacgaa tataaaaaaa
    19561 tagatgattt caacacgccg tggctggaag tacaggattt tttaagctaa aaaaatggcc
    19621 gacttcgcgt cggccatcag atatttactt cgccttcgct acagtaacca tcgccgcacg
    19681 aatcgtacga ccattcagcg tataaccctt ctgcataatg cccagtacgt tacctggcgc
    19741 aacgtcatca gattccacca ttgcgatagc ctgatgcaca ttcgggtcca gcggcacgtt
    19801 agtttcggcg atcacttcaa caccaaactt acgcacaaca tccagcatcg acttcagcgt
    19861 cagctcaatg ccttcaacca tcgcagacat atccgggtta gctttatcag ccacttccag
    19921 cgcacgatcc aggctatcaa tcaccggcag caattcgttg atgaatttct ccagcgcgaa
    19981 tttgtgggct ttttcaatat ccagttcagt acgtcgacgc aggttttcca tttcggcttt
    20041 tacacgcaaa atgccgtcac gttcacgggt ctgggcttca gccagctgag cttcgagatt
    20101 cgcaattttt tcatcgcgcg gatccacctg ctcagcagaa gcttctggct caactgcctc
    20161 aatctcttcg tgctgatcca tgataatttc ttccggggct tgcccctcag gcgttttctg
    20221 ttctttacta ctcatgaatt tctccgcgtt tttttcgcat tcatctcgct aacttcgctt
    20281 attatgggga tcagtttcag ggtttcaagg gaagcactca cattgtcatc aatcttcgca
    20341 acaaggacct cggaaaaatg aataatcatt tcaagtgtat tggcattgtg ggacacccac
    20401 ggcaccccac tgcactgaca acacatgaaa tgctctaccg ctggctgtgc acaaaaggtt
    20461 acgaggtcat cgttgagcaa caaatcgctc acgaactgca actgaagaat gtgaaaactg
    20521 gcacgctcgc ggagattggg caactagctg atctcgcggt agtcgttggt ggcgacggta
    20581 atatgctggg cgcggcacgc acactcgccc gttacgatat taaagttatt ggaatcaacc
    20641 gtggcaacct gggtttcctg actgaccttg accccgataa cgcccagcaa cagttagccg
    20701 atgtgctgga aggccactac atcagcgaga aacgtttttt gctggaagcg caagtctgtc
    20761 agcaagattg tcagaaacgc atcagcaccg cgataaatga agtggtgctt catccaggca
    20821 aagtggcgca tatgattgag ttcgaagtgt atatcgacga gatctttgcg ttttctcagc
    20881 gatctgatgg actaattatt tcgacgccaa caggctccac cgcctattcc ctctctgcag
    20941 gcggtcctat tctgaccccc tctctggatg cgattaccct ggtgcccatg ttcccgcata
    21001 cgttgtcagc acgaccactg gtcataaaca gcagcagcac gatccgtctg cgtttttcgc
    21061 atcgccgtaa cgacctagaa atcagttgcg acagccagat agcactgccg attcaggaag
    21121 gtgaagatgt cctgattcgt cgctgtgatt accatctgaa tctgattcat ccgaaagatt
    21181 acagttattt caacacatta agcaccaagc tcggctggtc aaaaaaatta ttctaatttt
    21241 acgccagcct ctttactgta tataaaacca gtttatactg tacacaataa cagtaatggt
    21301 ttttcataca ggaaaacgac tatgttggca caactgacca tcagcaactt tgctatcgtt
    21361 cgtgagcttg agattgattt tcatagcggc atgaccgtaa taactggcga gaccggcgcg
    21421 ggtaaatcta ttgcaataga tgccctcggt ctttgtctcg gtggtcgcgc tgaagccgac
    21481 atggtgcgta ccggcgctgc tcgcgctgac ctgtgcgccc gtttttctct gaaagatacg
    21541 ccagcggctc tgcgctggct ggaagaaaac cagcttgaag acgggcatga atgtttgctt
    21601 cgtcgcgtga tcagcagcga tggtcgctcc cgtggtttca tcaacggtac agctgttcct
    21661 ctgtcacaac tgcgcgaact gggtcagttg ctgattcaga tccatggtca gcacgctcat
    21721 cagttactca ccaaacccga gcaccaaaag ttcctgcttg atggctatgc caatgaaacc
    21781 tctctactcc aggaaatgac agcacgttat cagttgtggc atcaaagctg ccgtgacctc
    21841 gcgcatcatc aacagttaag tcaggaacgc gctgcccgtg cggaactgct gcaataccaa
    21901 ttaaaagaac ttaacgaatt taatccgcag cccggagagt ttgaacaaat cgacgaagag
    21961 tacaaacgtc tggcgaacag cggtcaattg ctgaccacca gccagaatgc attggcatta
    22021 atggccgacg gtgaagacgc aaacctgcaa agtcagcttt acacggctaa acaactggtg
    22081 agcgaattga ttggcatgga cagcaaactg tccggcgtac ttgatatgct ggaagaagct
    22141 accatccaga ttgctgaagc cagcgatgaa ctgcgccact actgcgatcg tctggatctc
    22201 gatcccaacc gactatttga acttgaacag cgcatctcaa aacagatttc gctggcacgt
    22261 aaacatcacg tcagccctga ggcattgcca cagtattacc agtcgctact ggaagaacag
    22321 cagcaactgg acgatcaggc cgactcacaa gaaacgcttg cgctggcggt aacgaaacat
    22381 catcagcagg cactggaaat cgcgcgcgca ttacaccaac aacgccagca atatgcagaa
    22441 gaacttgcac agctgatcac cgacagtatg catgcgctct caatgccgca tgggcagttt
    22501 acgatcgatg ttaaatttga cgagcatcac ctgggcgctg acggtgccga tcgtattgag
    22561 tttcgggtaa ccaccaaccc aggtcagcca atgcagccta ttgccaaagt cgcatccggt
    22621 ggtgaattgt cccgcatcgc actggcaatc caggtcatca cggcgcgtaa aatggaaacc
    22681 ccggcactga tttttgatga agtggatgta gggattagcg gtccaacagc ggcagttgtc
    22741 ggcaaactgc tgcgtcaact cggcgaatca actcaggtga tgtgtgttac ccacctgcca
    22801 caagtcgcgg gatgtggtca tcaacactat tttgtcagca aagaaaccga tggtgcgatg
    22861 acagaaacgc atatgcaatc cctgaataaa aaagcgcggt tacaagagct ggcgcgcctg
    22921 cttggtggca gtgaagtcac acgtaataca ctggcgaatg cgaaagaact gcttgcagcg
    22981 taaacttttt tcctgcttca cggtcagagt aaacagcaaa acgccgtaag accggaaagc
    23041 aaaaggtttt aaagtgatga aaggtctatt atcatcggca tattacagat gagccacgta
    23101 ctgctcgggc ccgaaaagga atcaaatcac tatgcgctgt aaaacgctga ctgctgcagc
    23161 agcagtacta ttgatgttga ccgcaggctg ttccactctg gagcgagtgg tttaccgtcc
    23221 tgacatcaac caggggaact atctgaccgc taacgacgta tccaaaatac gtgttggcat
    23281 gacgcaacaa caagttgcgt acgcattggg tacaccgctg atgtccgatc catttggtac
    23341 gaatacctgg ttctatgtct tccgccagca accaggtcat gaaggtgtaa cgcagcaaac
    23401 gctgacgctg acctttaaca gtagcggtgt gttgaccaat attgataaca aacctgcgct
    23461 gagtggtaac taataataaa gttgctctca aagacgttaa aaaaggtgct caatgagcac
    23521 cttttttctg tctgttattt attcgctgat ttttctgctc gttgcctgcg aagctctttc
    23581 ggatcggcaa tgagagggcg ataaatctcc acccgatcgc catcatgcac actatcgctt
    23641 agttttgccg gacggctgta aatgccgact ttgtttttag ttaaatcgat atcggtacgc
    23701 aattccagca agccactggc gcgaatagct tcttcaaccg tcgcgccctc ctgcagcgtc
    23761 acgcgctgca ggtactgctt ctcaggtagc gcataagcca cctcaacggc aattttacct
    23821 ggcactgtaa acctctttcg cacgaaccgt aaaagcctgg accatattag acgccagctc
    23881 tttaaacacg cgaccaaagg cgagttcaat caacttattg gtaaactcaa agtcgagatg
    23941 aaactcgata cgacacgcct cctggctcag cggcgtaaac ttccatccac caatcaattt
    24001 cttgaacggc ccatccacca gattcataag aatactttgg ttactggtca actggttgcg
    24061 ggtagtaaac gttttgctga tcccagcctt agagacatct accgccgcag tcatctgccc
    24121 aggagtggac tccagaatcc gacttccggt acaacccggc aaaaactgag gataagactg
    24181 aacgtcattc actaactgat acatttgctc cgcgctgtag ggtaccagtg cggtccggct
    24241 aatctgaggc ataacaattt ccatcaacaa aaatccaaca aataatatca tttatcctgc
    24301 tgtaaaaaaa acgctatccc ggcgctgggt aacatcgggt tcatgctaag atagagcctt
    24361 gtcccccgca ggattgatat ggggtgtttt cgatttcaga ttaccgatga ttcacgacgc
    24421 ttatgacgaa gaaaaaagca cataaacctg gttcagcgac catcgcgctt aacaagcgcg
    24481 cccgtcacga atactttatc gaagaagagt tcgaagcggg acttgccctg caaggctggg
    24541 aggttaaatc cctgcgcgca ggaaaagcca atatcagcga cagctacgtc cttctgcgtg
    24601 acggagaggc atttctgttt ggcgctaaca tcacgccaat ggccgtggcc tccacgcatg
    24661 tggtgtgcga tcctacccgt acccgcaagt tacttctcaa ccaacgcgaa ctggactcat
    24721 tgtacggtcg cgtcaatcga gaaggctata ccgtagtggc gctctccctg tactggaaaa
    24781 atgcctggtg caaagtgaaa atcggcgtcg ccaaaggtaa aaaacagcac gataaacgtt
    24841 cagatatcaa agaacgcgaa tggcaggtgg ataaagcacg tatcatgaaa aacgcccacc
    24901 gttaaacctg cactccaatt attgaccagt tcctcaccgc gcctccctct ccggcggcgc
    24961 gaatgaacat cttattggct atcacatccg acacaaatgt tgccatccca ttgcttaatc
    25021 gaataaaaat caggctacat gggtgctaaa tctttaacga taacgccatt gaggctggtc
    25081 atggcgctca taaatctggt atacttacct ttacacattg gggctgattc tggattcgac
    25141 gggatttgcg aaacccaagg tgcatgccga ggggcggttg gcctcgtaaa aagccgcaaa
    25201 aaatagtcgc aaacgacgaa aactacgctt tagcagctta ataacctgct tagagccctc
    25261 tctccctagc ctccgctctt aggacgggga tcaagagagg tcaaacccaa aagagatcgc
    25321 gtggaagccc tgcctggggt tgaagcgtta aaacttaatc aggctagttt gttagtggcg
    25381 tgtccgtccg cagctggcaa gcgaatgtaa agactgacta agcatgtagt accgaggatg
    25441 taggaatttc ggacgcgggt tcaactcccg ccagctccac caatcatgat tggacggtgt
    25501 aaggacaaca ccaacaaaaa caggaagtta gcagtctcag caggacaccg accagacggt
    25561 gaggagataa aaaaggatac gcaaaggagc cgtggctctc gagtgacaca aaagcccgct
    25621 tatgcgggct ttttgttttt cccttaagtt cctagccgct tatctataac tatggaaaaa
    25681 tgttaaccct gactgtatgt taacaaaggg atgtatatgt cggtttttca taactggctg
    25741 cttgatatcg caagcgggaa ttactttatc tacatcaaac gcctttctgc aaacgacaca
    25801 ggcgcaacag gtggccatca ggtcggactt tatatcccct caaatatcgt tgaaaagctt
    25861 tttccatcta tcaatcatac tcgcgaactg aacccttcag tcttccttac tgcgcatgta
    25921 tcatcccatg attgccctga tacccaagca cgcgcaattt attacaacaa ccgttatttt
    25981 ggtaagaccc gaaacgaaaa aagaattacg cgctggggga gaggaagtcc attacagaac
    26041 cctgaaaata caggagccct cacaattctt gctttcaggt taaacgaaca gaacactgac
    26101 tgttccgagg tagatatatg ggtctgcgtc aatcccgatg aagaggatat catcgagtct
    26161 gctattggcg aaatcatacc tggaacccta atttccggcc ctgccggaca aattttgggc
    26221 ggattgtctc ttcagcaaac tccagtaaat cataaatatg ttattcctga agactggaag
    26281 aagcgttttc cttctggaaa cgaaattatt caatatgctg ctggccatta tgctaaaaac
    26341 tccaaggatc cagatgagca actgattgac cgtcggcgtg tcgagtatga tatttttcta
    26401 ctcgtcgagg aattacatgt tattgatatt attaagaaag gattcgattc tgtagatgag
    26461 tttattgcat tagccaactc tgtcagtaat cgacgtaaat caagggcagg caaatcactt
    26521 gaacttcacc tagagaagct ttttatcgag cacggactac ggcatttctc cactcaggca
    26581 gttactgaag gtaataaaaa accagatttc ctgtttcctt cagcagaggc atatcataac
    26641 gttgaatttc ctgtagaaaa cttacgtatg ctggcagtaa agaccacctg caaagatcgc
    26701 tggcgtcaga tactgaatga agcagataaa atccatcagg tacatttatt tacactgcaa
    26761 gaaggtgttt cttcagcaca ataccgagaa atgaaagatg cgggtgtcag actcgttgta
    26821 ccatcaactt tacataaaaa atacccagaa gcagttagag aagaattaat aacgctcgga
    26881 gcattcatta ctgagctgat agagctttac gctgaactat cataggctga ctcccggctt
    26941 aaaaggccgg gagatgttct caaggctgcc cagtcttacc agcatcagca gaaacagctt
    27001 tgaggatata gggttccaga agtctggcaa cagcttcaaa tactggcacc acaactgagt
    27061 taccgaactg ccgatatgac tgagtatctg aaaccggaat acggaatggt ttccctccag
    27121 gtttttcaaa tcccataagg cgtgcgcact ctcggggagt cagcctgcgt ggtcgacgag
    27181 cctgattact ctcattcata aagtcagcct ctcccgttgc catatcccaa ccacgatcaa
    27241 taagaatttc tgatccgtct ttgtgatatc tggcagaaag tgtgcgtgca atgctttcct
    27301 tattctcagg attgaccaac ccaaagccaa aaccattccc cttggctgca tgctttttgg
    27361 cgtagttata aaggtactcc catagttttg gcgtaagtat atatttactg tcgactacag
    27421 gctccagcaa ttcaccaaat gatgggcggt gttccggata aaaacgactg atatcacgca
    27481 aggtaaaccc cttgtgaata ttcagatctc gtctaaatcc gaccagaaca atgcgttcac
    27541 gatgctgagg caaaaaatgc ttcccatcga taatctttgg atcgtttttt cccatttctg
    27601 cagcatcggc aacttcgtag cccagctcgt caagggtctc cataatgact ttgaaagttt
    27661 tacccttatc atggctcttc agatttttga cattttccag cacaaaaatt gccggttttt
    27721 ttgctcgtat aatacgtgcc acgtcaaaaa aaagtgttcc ttgtgcttca cattcaaaac
    27781 catgcgcacg accaagtgag tttttcttac taacaccagc aaggctaaat ggctggcacg
    27841 ggaaccccgc aagaagcaca tcatgatccg gcacatgctc atcaatatat gcataagcat
    27901 ccgtttccaa tacatcggtt ttatcactca gcgtgacttc ccgaatatcg agattgaatt
    27961 tatgcacctg ttcatcgtta aaccagttgg ccttgtatgt acgcacagca tctttattcc
    28021 attcactggt aaaaacacac tggcctccaa tggcctcaaa acctttccgt atccctccaa
    28081 ttccagcaaa taagtcaatg aagcggaaag catattccgg atggtttgca ggtggttctg
    28141 gtagcatctt acgcagaaga gactcttcta ctgaagtcaa cgattttggt aaacacttgc
    28201 cattaatcca gcggttaatg gtttcacggc tccactcatt ttttccgact tttctcagta
    28261 attcagccac atacttctga tcatagattt ccagcacttt ctcgataagc tttttatcat
    28321 tttcctgtcg cagcttttct tccgcctcgg cttccttcag cagatgctgt gccaacactt
    28381 caaattcaga cataattcct ccaaggggtc taatgggtga aactttatca ctcattcaac
    28441 ccagaaggaa atgttttatc tggatattta aacagtgact acaacgtaat ctagcactgg
    28501 tgatgctttg ttaggcatag agaatcattc tatatacgac taatgacaga aaaacagcag
    28561 acaagtagtt tgttcataaa ttaacgcata ctatgtgtct acggttttcg agaccggtcc
    28621 aatcatcaaa cgaaacataa aattagctca cattatgagg aaaagtatct tttttgtact
    28681 atgtaaattc aaaggcttag cctcatttct ccgatggttt tctcaacact actggttgtg
    28741 agcccttgca atgatcatta atatacgtct cacaaataat tcttcataga tattgcaaaa
    28801 tggatattac tgagtttcct tctggagtaa ttgaacacct tggctggtat gtataccgat
    28861 tgattgatcc gagggacgga agcaccttct atgtagggaa aggcaaaggt aaccgcgtat
    28921 ttgcccatat gcgcggtgaa gtggcagcga ctgatgatga cgagttactg agcaacaagc
    28981 taaagcaaat tagagaaata aggttagcag gacttgaagt tatccatgtc atccatcgac
    29041 acggaatgac tgatgaaaag acggcgtacg aagttgaagc tgcacttatt gatgcctacc
    29101 ctgggttaac gaatatcatg aatggtgctg gcagcaatga attcggcgcc gcgcatgtca
    29161 aagagttgat agcaacatat caacccgaaa ccataatatt tcatcataaa gcattaatga
    29221 tttccgttaa cagaagtgca aaggattcag agctttatga tgcggttcga tttagctggc
    29281 gcattaatgt ctctcgcgcc agccaagcag aagtcattct tgctactgta agggggatcg
    29341 ttcgaggggt tttcattgct gataaatggc tcaaatcaac acgtgaaaat ttccctacga
    29401 tgaaatactg ggacgaggat cctgactttg aggcaacaca aagttctcgc tatggttttg
    29461 aaggtcgaga agccccacct gaaatagcaa atctttatct tggaaaaaaa ataccagatg
    29521 aattaagaaa aaaaggagct atgtccccgg tccgttactc acctaatttt tgagtcttta
    29581 agtgataagc ataaaccgca gcacgatctt gcatacgacg tgctacggtt tcatttatct
    29641 ccgaccgaaa acttcttata cagtgtcgat ataccaacat catagatgat cgccaccttc
    29701 tggcgaggaa cgcctgatgc aattaatcgc ccagcctgcg cccattgttc tggtgtaagt
    29761 ttgggacgac gtccaccaat tcgtccctgt gcgcgagcag cttccagtcc agcttttgtt
    29821 cgttcaacaa tcagttctcg ttccatttca gccagggcac ccatcacatg aaagaaaaaa
    29881 cgccccatcg gtgtgctggt atcaatagca tccgtcaggc tgcgaaaatt aacgccacgt
    29941 tcgcgcaact cctcaaccag aatgaccaga tgccgcatac tacgccccag ccgatccagc
    30001 ttccagacaa ccagagtgtc accttccgat aatgtcctga gcagtttttt cagtcccggc
    30061 ctttcagact ttgtaccgct tatcttgtct tcaaaaatca gctcgcatcc tgcacagttc
    30121 agcgcattac gctgtagatc tgtgttctgg tcatttgttg acacacgtac atagccaata
    30181 agcatggtag atctccctga caaaagcagg aatgatgcca tttgctcgtt atttctgcat
    30241 tttcataaac gttggtttgg gagaagcggc gaaaagggat gtaggcacag gagaaaatca
    30301 gataccggat atgtcagcct ggaaaagaaa tccgagttct aatcgctgga gaaaattgcc
    30361 tgatggaacc atcattcaaa tgggaatatc agcatcaggg ccattaggct cacctgtaaa
    30421 tatcaccctg ccgatatctt tcagcaatac caattattgt gttgttgcat cgtacgataa
    30481 tgcacggtca ggtgtgtcaa caatggttag ttttgcagca ttacctgttt caccatcgca
    30541 attttccctg atgtcatctg tgactgagca aggaataaat ccttttgctt actggattgc
    30601 ttttggagat tgataaatgg acagatactt ctattcacaa aaagaaaatg gtttttttac
    30661 cgatttaaat aaagcacctt cagatgctgt tgagataacc acggatgaat ggctgtcact
    30721 actggatggt caggataatg gcatgaaaat agtcagcaat caggagggat atccggtttt
    30781 gacagagcaa ccacctttat caaaagaaaa ccttattgca ttggcagagt tgaaaaaagg
    30841 aaaacttatt aatgaagcca acgagcacat gaacagcagg caatggcctg gtaaagcggc
    30901 tattggtcgt ctgaaaggtg aggaactggc gcaatataat ttgtggct
//
LOCUS       DAZUDJ010000059        30610 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.059, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000059 DAZUDJ010000000
VERSION     DAZUDJ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30610
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.059"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1034
                     /locus_tag="ACHY1N_003508"
     CDS             <1..1034
                     /locus_tag="ACHY1N_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1-like element ISEc1 family transposase"
                     /protein_id="HFS4045742.1"
                     /translation="AVISGAESWEDIEDFGETHLDFLKQYGDFENGIPVHDTIARVVS
                     CISPAKFHECFINWMRDCHSSDDKDVIAIDGKTLRHSYDKSRRRGAIHVISAFSTMHS
                     LVIGQIRTDEKSNEITAIPELLNMLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAV
                     KGNQGRLNKAFEEKFPLKELNNPEHDSYAISEKSHGREEIRLHIVCDVPDELIDFTFE
                     WKGLKKLCGAVSFRSIIAEQKKEPEMTVRYYISSADLTAEKFATAIRNHWHLENKLHW
                     RLDVVMNEDDCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLA
                     SVLAGSGLS"
     gene            complement(1258..2025)
                     /gene="yafV"
                     /locus_tag="ACHY1N_003509"
     CDS             complement(1258..2025)
                     /gene="yafV"
                     /locus_tag="ACHY1N_003509"
                     /EC_number="3.5.1.111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001758752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutaramate amidase"
                     /protein_id="HFS4045743.1"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAL
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMAVLREYRDKFPAWRDADEFRL"
     gene            2206..2652
                     /gene="ivy"
                     /locus_tag="ACHY1N_003510"
     CDS             2206..2652
                     /gene="ivy"
                     /locus_tag="ACHY1N_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308274.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ivy family C-type lysozyme inhibitor"
                     /protein_id="HFS4045744.1"
                     /translation="MFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQG
                     HKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFS
                     TIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     gene            complement(2695..5139)
                     /gene="fadE"
                     /locus_tag="ACHY1N_003511"
     CDS             complement(2695..5139)
                     /gene="fadE"
                     /locus_tag="ACHY1N_003511"
                     /EC_number="1.3.8.7"
                     /EC_number="1.3.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0033539 - fatty acid beta-oxidation using
                     acyl-CoA dehydrogenase [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase FadE"
                     /protein_id="HFS4045745.1"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     gene            5379..5957
                     /gene="lpcA"
                     /locus_tag="ACHY1N_003512"
     CDS             5379..5957
                     /gene="lpcA"
                     /locus_tag="ACHY1N_003512"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008968 - D-sedoheptulose 7-phosphate
                     isomerase activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HFS4045746.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            6163..6930
                     /gene="yafJ"
                     /locus_tag="ACHY1N_003513"
     CDS             6163..6930
                     /gene="yafJ"
                     /locus_tag="ACHY1N_003513"
                     /EC_number="2.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HFS4045747.1"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     gene            complement(6901..7641)
                     /gene="dpaA"
                     /locus_tag="ACHY1N_003514"
     CDS             complement(6901..7641)
                     /gene="dpaA"
                     /locus_tag="ACHY1N_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan meso-diaminopimelic acid protein
                     amidase"
                     /protein_id="HFS4045748.1"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     gene            complement(7797..8075)
                     /gene="yafQ"
                     /locus_tag="ACHY1N_003515"
     CDS             complement(7797..8075)
                     /gene="yafQ"
                     /locus_tag="ACHY1N_003515"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafQ"
                     /protein_id="HFS4045749.1"
                     /translation="MIQRDIEYSGQFSKDVKLAQKRHKDMNKLKYLMTLLINNALPLP
                     AVYKDHPLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGTHAALFG"
     gene            complement(8078..8338)
                     /gene="dinJ"
                     /locus_tag="ACHY1N_003516"
     CDS             complement(8078..8338)
                     /gene="dinJ"
                     /locus_tag="ACHY1N_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin DinJ"
                     /protein_id="HFS4045750.1"
                     /translation="MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVARE
                     KALPFDLREPNQLTIQSIKNSEAGVDVHKAKDADDLFDKLGI"
     gene            8524..9297
                     /gene="yafL"
                     /locus_tag="ACHY1N_003517"
     CDS             8524..9297
                     /gene="yafL"
                     /locus_tag="ACHY1N_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308281.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFS4045751.1"
                     /translation="MHDQPLLSMSLPSIPSFVLSGLLLLCLPFSSFASATTSHITFSY
                     AARQRMQNRARLLKQYQTHLKKQASYIVEGNAESRRALRQHNREQIKQHPEWFPAPLK
                     ASDRRWQALAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDQGFDCSGLVF
                     YAYNKILEAKLPRTANEMYHYRRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDG
                     QFIESPRTGETIRVSRLAEPFWQDHFLGARRILTEETIL"
     gene            complement(9354..9710)
                     /locus_tag="ACHY1N_003518"
     CDS             complement(9354..9710)
                     /locus_tag="ACHY1N_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFS4045752.1"
                     /translation="MNKASNIITIKGQPAAVTFEADINAFRGKFLNVNGYCDFVATSI
                     EALYREGESALDEWMADCEEDGIAPFREEEEQKRLTLRVPHHIDSRLTIVARQHSISK
                     NQLIVDVLEREFSAQM"
     gene            complement(9703..9981)
                     /locus_tag="ACHY1N_003519"
     CDS             complement(9703..9981)
                     /locus_tag="ACHY1N_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFS4045753.1"
                     /translation="MIKVSALGSRHRKTFDDVMTEPPKSGIKWDDVVALIKAVGGTIK
                     NNNGSRRKFQIGTTKFSTHEPHPKNVMDKGAVAGLKEWFVNCVGVDYE"
     gene            complement(10086..11798)
                     /locus_tag="ACHY1N_003520"
                     /pseudo
     CDS             complement(10086..11798)
                     /locus_tag="ACHY1N_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA];
                     GO_process: GO:0071978 - bacterial-type
                     flagellum-dependent swarming motility [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
     gene            11770..12555
                     /gene="lafU"
                     /locus_tag="ACHY1N_003521"
     CDS             11770..12555
                     /gene="lafU"
                     /locus_tag="ACHY1N_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /protein_id="HFS4045754.1"
                     /translation="MTTIKLIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSH
                     PPKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSITTIARDAHMEANLEME
                     IVPQGLRVLIKDDQNRNMFERGSAQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMA
                     YKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDSKNPKSAGNRRI
                     EIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     gene            12626..13681
                     /gene="dinB"
                     /locus_tag="ACHY1N_003522"
     CDS             12626..13681
                     /gene="dinB"
                     /locus_tag="ACHY1N_003522"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFS4045755.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFSELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     gene            13678..14130
                     /gene="yafP"
                     /locus_tag="ACHY1N_003523"
     CDS             13678..14130
                     /gene="yafP"
                     /locus_tag="ACHY1N_003523"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4045756.1"
                     /translation="MNNIQIRDYQPGDFQQLCAIFIRAVTMTASQHYSPQQIAAWAQI
                     DESRWKEKLAKSQVRVAVINAKLVGFITCVEHYIDMLFVDPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGEWFINFYMRYKQQH"
     gene            14376..15515
                     /locus_tag="ACHY1N_003524"
     CDS             14376..15515
                     /locus_tag="ACHY1N_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HFS4045757.1"
                     /translation="MGNYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVG
                     MPDLHPGRGYPIGAAFFSVGRFYPALVGNDIGCGMALWQTDILARKYNADKFEKRLSD
                     LDDVAEESWLEENLPSAFAQHPWRSSLGSIGGGNHFAELQQVDQIINAELFALAGLDA
                     QHLQLLVHSGSRGVGQSILQRHIASFSHHGLPQGSDDALRYIAEHDDALAFACINRQM
                     IALRIMQQVKATGSPVLDVAHNFVSACQIGEQQGWLHRKGATPDDNGLVIIPGSRGDY
                     SWIVQPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICRDKQL
                     IFEEAPQAYKSAESVVQCLVQAGLIIPVARLRPVLTLKNSGGKKG"
     gene            15512..16126
                     /gene="prfH"
                     /locus_tag="ACHY1N_003525"
     CDS             15512..16126
                     /gene="prfH"
                     /locus_tag="ACHY1N_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HFS4045758.1"
                     /translation="MILLQLSSAQGPEECCLAVKKALDRLIKEAARQDVAVTVLETET
                     GRYSDTLRSALISLDGDNAWALSESWCGAIQWICPSPYRPHHGRKNWFLGIGRFTADE
                     QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWKLEQQQQENSAVLKSQRRMFHHQIERGNPRRTFTGMAFIEG"
     gene            complement(16183..17640)
                     /gene="pepD"
                     /locus_tag="ACHY1N_003526"
     CDS             complement(16183..17640)
                     /gene="pepD"
                     /locus_tag="ACHY1N_003526"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HFS4045759.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVL
                     KSLMNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            17901..18359
                     /gene="gpt"
                     /locus_tag="ACHY1N_003527"
     CDS             17901..18359
                     /gene="gpt"
                     /locus_tag="ACHY1N_003527"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000310 - xanthine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFS4045760.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            18451..19695
                     /gene="frsA"
                     /locus_tag="ACHY1N_003528"
     CDS             18451..19695
                     /gene="frsA"
                     /locus_tag="ACHY1N_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HFS4045761.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDDA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITGWIEKRLC"
     gene            19753..20154
                     /gene="crl"
                     /locus_tag="ACHY1N_003529"
     CDS             19753..20154
                     /gene="crl"
                     /locus_tag="ACHY1N_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045893 - positive regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HFS4045762.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     gene            complement(20193..21248)
                     /gene="phoE"
                     /locus_tag="ACHY1N_003530"
     CDS             complement(20193..21248)
                     /gene="phoE"
                     /locus_tag="ACHY1N_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HFS4045763.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     gene            21536..22639
                     /gene="proB"
                     /locus_tag="ACHY1N_003531"
     CDS             21536..22639
                     /gene="proB"
                     /locus_tag="ACHY1N_003531"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFS4045764.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            22651..23904
                     /gene="proA"
                     /locus_tag="ACHY1N_003532"
     CDS             22651..23904
                     /gene="proA"
                     /locus_tag="ACHY1N_003532"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFS4045765.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLGEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGSVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     gene            24019..24094
                     /locus_tag="ACHY1N_003533"
     tRNA            24019..24094
                     /locus_tag="ACHY1N_003533"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24052..24054,aa:Thr,seq:cgt)
     gene            complement(24221..24559)
                     /locus_tag="ACHY1N_003534"
                     /pseudo
     CDS             complement(24221..24559)
                     /locus_tag="ACHY1N_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014831000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
     gene            complement(24610..25566)
                     /gene="paoD"
                     /locus_tag="ACHY1N_003535"
     CDS             complement(24610..25566)
                     /gene="paoD"
                     /locus_tag="ACHY1N_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor insertion chaperone PaoD"
                     /protein_id="HFS4045766.1"
                     /translation="MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAVLV
                     TLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEAAAAFEALEMMGSGRDREIRYGE
                     GSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPAGLRYDPQAQSLVCLPTQ
                     TRTGWNLNGFEVGFRPCVRLMIYGRSLETQATASLAAATGYDSHIFDLFPASASAQID
                     TDTAVILLCHDLNRELPVLQAAREAKPFYLGALGSYRTHTLRLQKLHELGWSREETTQ
                     IRAPVGIFPKARDAHTLALSVLAEVASVRLHQEEDSCLPPSS"
     gene            complement(25576..27774)
                     /gene="paoC"
                     /locus_tag="ACHY1N_003536"
     CDS             complement(25576..27774)
                     /gene="paoC"
                     /locus_tag="ACHY1N_003536"
                     /EC_number="1.2.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidoreductase molybdenum-binding
                     subunit PaoC"
                     /protein_id="HFS4045767.1"
                     /translation="MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEE
                     APNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLGG
                     PTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDK
                     NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRT
                     DLAKTLKVPVENVRIISPYIGGGFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIP
                     NNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAVQQSELLYAGANRHT
                     GLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADP
                     TRCFSRRQLIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGAR
                     VHLEQNGTVTVETDMTDIGTGSYTILAQTAAEMLGVPLEQVAVHLGDSSFPVSAGSGG
                     QWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEATAGGRL
                     TAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARS
                     QVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPIS
                     SPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPITLDKLLDKLPDVV"
     gene            complement(27771..28727)
                     /gene="paoB"
                     /locus_tag="ACHY1N_003537"
     CDS             complement(27771..28727)
                     /gene="paoB"
                     /locus_tag="ACHY1N_003537"
                     /EC_number="1.2.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidoreductase FAD-binding subunit
                     PaoB"
                     /protein_id="HFS4045768.1"
                     /translation="MKAFTYERVNTPAEAALSAQRVPGAKFIAGGTNLLDLMKLEIET
                     PTHLIDVNGLGLDKIEVTDAGGLRIGALVRNTDLAAHERVRRDYAVLSRALLAGASGQ
                     LRNQATTAGNLLQRTRCPYFYDTNQPCNKRLPGSGCAALEGFSRQHAVVGVSEACIAT
                     HPSDMAVAMRLLDAVVETITPEGKTRSITLADFYHPPGKTPHIETALLPGELIVAVTL
                     PPPLGGKHIYRKVRDRASYAFALVSVAAIIQPDGSGRVALGGVAHKPWRIEAADAQLS
                     QGAQAVYDALFASAHPTAENTFKLLLAKRTLASVLAEARAQA"
     gene            complement(28724..29413)
                     /gene="paoA"
                     /locus_tag="ACHY1N_003538"
     CDS             complement(28724..29413)
                     /gene="paoA"
                     /locus_tag="ACHY1N_003538"
                     /EC_number="1.2.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0047770 - carboxylate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase iron-sulfur subunit PaoA"
                     /protein_id="HFS4045769.1"
                     /translation="MSNQGEYPEDNRVGKHEPHDLSLTRRDLIKVSAATAATAVVYPH
                     STLAASVPAATPAPEIMPLTLKVNGKTEQLEVDTRTTLLDALRENLHLIGTKKGCDHG
                     QCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFIKHDGFQCGY
                     CTSGQICSSVAALKEIQDGIPSHVTVDLVSAPETTADEIRERMSGNICRCGAYANILA
                     AIEDAAGEIKS"
     gene            29831..30443
                     /gene="yagU"
                     /locus_tag="ACHY1N_003539"
                     /pseudo
     CDS             29831..30443
                     /gene="yagU"
                     /locus_tag="ACHY1N_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308344.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
BASE COUNT         7301 a         7889 c         8019 g         7401 t
ORIGIN      
        1 ttgccgttat ttctggtgca gaaagttggg aagatataga ggatttcggg gaaacacatc
       61 tcgatttctt gaagcaatat ggtgattttg aaaatggtat tcctgttcac gatactattg
      121 ccagagttgt atcctgtatc agtcctgcaa aatttcatga gtgctttatt aactggatgc
      181 gtgactgcca ttcttcagat gataaagacg tcatcgcaat tgatggaaaa acgctccggc
      241 actcttatga caagagtcgc cgcaggggag cgattcatgt cattagtgcg ttctcaacaa
      301 tgcacagtct ggtcatcgga cagatcagga cggatgagaa atctaatgag attacagcta
      361 tcccagaact tcttaacatg ctggatatta aaggaaaaat catcacaact gatgcgatgg
      421 gttgccagaa agatattgca gagaagatac aaaaacaggg aggtgattat ttattcgcgg
      481 taaaaggaaa ccaggggcgg ctaaataaag cctttgagga aaaatttccg ctgaaagaat
      541 taaataatcc agagcatgac agttacgcaa ttagtgaaaa gagtcacggc agagaagaaa
      601 tccgtcttca tattgtttgc gatgtccctg atgaacttat tgatttcacg tttgaatgga
      661 aagggctgaa gaaattatgc ggggcagtct cctttcggtc cataatagca gaacaaaaga
      721 aagagccaga aatgacggtc agatattata tcagttctgc tgatttaacc gctgagaaat
      781 tcgccacagc gatccgaaat cactggcact tggagaataa gctgcactgg cgtctggacg
      841 tggtaatgaa tgaagacgac tgcaaaataa gaagaggaaa tgcagcagaa ttattttcag
      901 ggatacggca cattgctatt aatattttga cgaatgataa ggtattcaag gcagggttaa
      961 gacgtaagat gcgaaaagca gccatggaca gaaactatct ggcgtcagtc cttgcgggga
     1021 gcgggctttc gtaatcttgc cctggcgtta aacacatgtt atatagaaga agtgcttgca
     1081 tcctgctcag agcttgggtt tcgaactgac aaaatgaaaa atttaacaca aatttaattc
     1141 atgctcttgc cctgcggggg gattattaaa tcttcccagt tttttattat ttaactctcg
     1201 ctcagcacac taaacatccc tttctgaatt ccccgcccta aatacagccc ccactcacta
     1261 caacctaaac tcatccgcat cccgccatgc cggaaactta tcgcgatatt cccttaacac
     1321 cgccatcgac agctcggcat caatgcgcgt tgcctgatgc gcgtcggcag tagcgataat
     1381 ctcgccttgt ggattaatca cccggctgtc accgcgataa tggcagccgt tgccatcgct
     1441 gccgacgcga ttgcatcccg ccacatacgc ctgattctca atcgcgcggg ccgtcagcaa
     1501 tgcctgccag tgcagagagc gcggagcagg ccagttggcg acgtacaggg cgaggtcata
     1561 atcgttgaga ttgcgcgacc acacaggaaa acgtaagtcg tagcacacca gcggcaaaat
     1621 acgccagccg cgccattcca caatcactcg cgcattgccc gctttataat gtagatgctc
     1681 atctgccatg cggaacagat gacgcttatc ataaaaatgt accgtgccgc ccggctcaac
     1741 cagcaaaaag cggttaaccg aaccagactc cgtttgtaat gcaacactgc ctgcaatcag
     1801 cgcattgcac tgctgcgcct tagctgtcat ccagttcact acgtcatctt gtgctagcga
     1861 cgaagctgcc gcttccatgg caaagccgct ggtaaacatc tccggtagaa cgatcacatc
     1921 gcgcccggta ataccttcca gttgacgatc aaaatgacgc aggttggcag ggccatccat
     1981 ccacaccagt ggttgctgca aaagcgtaat cttcaaacca ggcacggtgt acaactcctt
     2041 tatgcgaagg gttttataac tttaacacct tatcaggcag ttgccttagc gcagaataaa
     2101 ttgataacaa atgctgatat tggaaatatc tgatttgcaa attatcgtgt tatcgccagg
     2161 ctttagaagg ttaataacat gggcaggata agctcgggag gaatgatgtt taaggcaata
     2221 acgacagtcg ccgctctggt catcgccacc agtgcaatgg cgcaggatga tttaaccatt
     2281 agcagccttg caaagggcga aaccaccaaa gctgcattta atcagatggt acaagggcat
     2341 aagctgcctg cctgggtgat gaaaggcggt acttatactc ccgcacaaac cgtaacgttg
     2401 ggagatgaga cgtatcaggt gatgagcgcg tgcaaaccgc atgactgtgg ctcgcaacgt
     2461 atcgctgtga tgtggtccga gaaatctaat cagatgacgg ggctgttctc gactattgat
     2521 gagaaaacgt cgcaagagaa actcacctgg ctgaatgtga acgatgcgct ttcgattgat
     2581 ggtaaaacgg tgctgttcgc ggcgttgacc ggcagcctgg aaaaccatcc ggatggcttt
     2641 aattttaaat aattagcgga taaagaaacg gagcctttcg gctccgttat tcaattacgc
     2701 ggcttcaact ttccgcactt tctccggcaa ctttaccggc ttcgtcgcca gctcttccgg
     2761 atcaaagtca tcaacgttaa tactgcgcag acggctttct tcagctttca ccagaatagc
     2821 ggcttcatct ttatcaatca gccccttcgc cagcgcgttg tgcgccagtt catccagacg
     2881 ggtaaacggc aggtttttac ccagctcttt acagatccgc tgatgaattg ggtcggcggc
     2941 aatcacatcc accagcgcct cttccagcaa gccaaccgga ttatgctcgc tcggcgtcag
     3001 gtactgaccg cgaccaatgc gggaacgggt ggcgttcggc acttgtaaaa tcttcgccac
     3061 tttatgatcc agcttgtcag aaggtgccag ataatgacgt ccggtcggga agatcaccac
     3121 attcagcagc ccggcaacca cgcggttcgg gaagttttgc agtaaatcat ccatcgcctg
     3181 ttcagcctga tacagcgcat cttgtacgcc ccagtgcacc agcggcaggt cggcttcatt
     3241 acggccttcg tcgtcataac gcttcagaac ggcagaggcg aggtaaagct ggcttaaaat
     3301 atcccccaga cgtgccgaga tgcgctcacg acgtttcagg ctgccgccca gcacagccat
     3361 cgagacatca gaaagcaggg cgaggttggc gctcaggcgg ttcaggtgct gatagtagcg
     3421 tttagtggca tcgccggttg gcgtgctgct ggttaaaccg cgcgtcaggc ccagccagaa
     3481 gctgcgaact ttgttgctac cgacgtgacc gatatgtttg aacaacagtt tatcgaacgc
     3541 gttgacgtca ttgttcttcg ctgcttccat ctcttccagc acgtacggat ggcaacgaat
     3601 cgctccttgt ccgaagatca tcatgctgcg ggtcagaatg ttggcccctt caacggtgat
     3661 ggcaatcggt gcgccctggt aagcacgcgc caggaagttg ctctgcccga gcataatgcc
     3721 tttgccacca gtgatatcca tcgcatcaat aatcgactgc tgcccgcggt gggtacagtg
     3781 atacttaacg atagccgaca gcacggcagg tttttcgccg agcataatgc cgtaggtaat
     3841 cagcgatgcc gcagcatcca tcacgtaggc attaccggca atacgcgcca gcggctcttc
     3901 aatcccttcc atcttaccga tagagatttt gaactgacgg cgaatgtgag catacgcgcc
     3961 cgttgccagc gctaccgatt tcacgccgcc ggttgagttg gaaggcaggg tgatgccgcg
     4021 gcctaccgag aggcactcca ccagcatccg ccagccttgc ccggccattt tcggcccacc
     4081 gatgatgtaa tcgatcggta cgaagacatc tttaccgcgc gtcggtccgt tctggaacgg
     4141 tacgttcagc gggaagtggc gacgaccaat ttccacgccc ggcgtggtgg tcgggatcag
     4201 cgcacaggta atacctaaat cttctgcgcc acccagcagc ttttccgggt cggagagttt
     4261 aaacgccagc ccaagcacag tcgcaatcgg tgccagcgta atgtagcgtt tgttccaggt
     4321 cagacgcatc cccagcacct gctggccctg ccattcgccc atgcagacaa tcccggtgtc
     4381 cggaatcgcg cccgcatcgg aacccgcttc cgggctggtc agtgcaaagc aggggatctc
     4441 ctgaccacgc gccagacgcg gcagatagtg atctttctgc tcgtcagtgc cgtaatgttg
     4501 caacagttcg cccgggccta atgagtttgg cacgccgacg gtaatcgcca ggatcccgct
     4561 cacgccggag agtttttgca gcacgcgaga ctgggcataa gccgagaact ccagcccgcc
     4621 gtactctttt ttgatgatca tcgcgaagaa acgatgctct ttaaggtacg cccacaactc
     4681 cggcggcaga tccgccagct catgggtgat ctggaaatca ttcgccatcc ggcaggcttc
     4741 ttctaccggg ccgtcgagaa acgcttgctc ttcggcggtc aggcgcggct gcggatagtt
     4801 atgcagcttt ttccagtccg gcttgccctg gaacaagtcg ccctcccacc aggtggtgcc
     4861 cgcatcaatc gcttctttct cagtgcgcga catcggcggc atcaccttac ggaaaccgcg
     4921 aaataccggc gcggaaatca tcgacttacg cataggcgca aagttaaatg gcacgaggat
     4981 aatggccaga ggcaccagta cccacgccga ccacagacca gcaacgccga gggcggctgt
     5041 ccaggcgagc aaaatcagac tgctgataaa taagctcacg cggtgataga acaacgcgcc
     5101 gagcaggaca accgtagcga gaatactcaa aatcatcata acgaaaagcc ccttacttgt
     5161 aggaggtctg accacttgtg atgatatggt tgtagtggat gtaaaaacat ttagcaatgt
     5221 gtttacaata taattacaac aaagctcaca ttgttgctgt ttttatccgc acttcaggtc
     5281 aaaaagtcct ggtcatagca cctgcccgta cttctcgctt ttggcggtat ccggtacact
     5341 gcattttgtc tattacattt atgctgaagg atatcctcat gtaccaggat cttattcgta
     5401 acgaactgaa cgaagcggcg gaaacgctgg ctaacttttt aaaagatgac gccaatattc
     5461 acgccattca gcgcgcggcg gtcctgttag cagacagctt taaagccggt ggcaaagtgc
     5521 tttcctgcgg caacggcggt tcccattgcg acgctatgca ctttgccgaa gagttgaccg
     5581 gtcgctaccg tgaaaaccgt ccgggctacc cggcgattgc tatttctgac gttagtcata
     5641 tttcctgcgt cggtaatgat ttcggtttca atgatatttt ctcccgctac gttgaagcgg
     5701 taggtcgcga aggcgatgta ctgctgggga tctccacctc cggtaactct gcaaacgtga
     5761 tcaaagcgat cgcagcggcg cgtgagaagg ggatgaaagt gatcaccctg accggtaaag
     5821 acggcggcaa aatggctggc acggcggata tcgaaattcg cgtaccgcac tttggttatg
     5881 ccgaccgcat tcaggagatt cacattaaag tgatccatat cctgatccag ttaattgaaa
     5941 aagagatggt taagtaagtc tggcgtaggc tggataaggc gtttacgccg catccggcac
     6001 ttgtgcgctg atgcctgatg cgatgctgac gcgtcttatc atgcctacaa atctgtaccc
     6061 gaaccgtagg ccgaataatt cgtttacgcc gcatccgacc tgaaaattct taaatcaatc
     6121 ttcgccgggg gccattcgct cccgctgttg tggaggttac ccatgtgcga attgctcggg
     6181 atgagcgcca acgtccctac cgatatctgc tttagtttca ccggacttgt acagcgtggt
     6241 ggtggaaccg ggccacataa agatggctgg ggcattacct tttacgaagg taaaggctgt
     6301 cgcacattta aagatccaca acccagcttt aattccccca tcgccaaact tgtccaggac
     6361 tacccgataa aatcctgttc ggtggtggct catattcgcc aggctaatcg gggcgaggtg
     6421 gcgctggaaa atactcaccc atttacccgc gagttatggg ggcgtaactg gacttatgcc
     6481 cataacggac aactgacggg ctacaaatca ctggaaaccg gcaacttccg cccggtcggt
     6541 gaaaccgata gcgaaaaagc cttctgctgg ctcctgcata aattaacgca gcgttacccg
     6601 cgcacaccgg gcaacatggc ggcagtgttt aaatatatcg cctcactggc ggatgaactg
     6661 cggcagaagg gcgttttcaa catgctgctt tctgacgggc gctatgtgat ggcgtattgc
     6721 tcgactaatt tacactggat cacccgccgc gcgccgtttg gcgtggcaac gctgctggat
     6781 caggatgtgg aaatcgactt cagctcgcag accacaccga atgatgtggt cacggtgatt
     6841 gcaacacagc cgctgacggg caatgaaacc tggcaaaaga ttatgccagg cgaatggcgc
     6901 ttattttgcc tcggggagcg tgtagtttga tgccagttgt ggctgcacaa cttcgtggct
     6961 taacggcttg ctgaccacgt aacggccatt gaccacagaa acggtcggtg gcttacgggt
     7021 ttgctcaaag tagtcgtagc ccggcttcag ctgctcccag aagtccttaa agttggaata
     7081 tttatggcgc ttcatattgg cgtcggtcat gcggaacggg taaatactca cttgcacgct
     7141 cggctgacca aacaccagcg caccagtaac gaactggaag atctcatcaa taccctgatt
     7201 ggtcattgcg tagcagccga tggaaacaca atcgccgtgg atcatcaggt atttcccttc
     7261 ataaccatgc gcacggtcat aggcattggg gaaaccaata ttaatcgctt tgtagtaacg
     7321 gctgtctggt tttaactgat tacgctggac gctataaaac ccttccgggc ttttgaaatc
     7381 gccctgacgc tgttttggcc ctaagccgcc ggaatattta cagattttat aactgtcgag
     7441 cagctgatat tgctcgccca ttttgacgta gagatcgagc gtacgttctt ccttgaagat
     7501 ctggatgtag acaggggatc ccatcaactg ctgcttatac tctttgctca ctggcgtggt
     7561 cgagctactg ctgcccagca aaccggcaaa cgaaacgcac gggatcaaca acatcgcaag
     7621 aattaatgcg attttacgca tactgcttat tccttgataa aacggttaca cacgccagga
     7681 cggcaaaata gatcccaaat cggaatagtc tggatttgga aggctcacat tatcaccaaa
     7741 agagttttac gcaagcctgt cggcgcaggg tttacaaatt tcatcggcag cgtgctttac
     7801 ccaaagagcg ccgcgtgagt tccagttctc tcaaatcgta aaagtttatc ggtaagtttg
     7861 taaatcagga tccagtccgg ttcgacatga gcatcgcgat aacctttcca tgaaccttgc
     7921 agcgggtggt ctttataaac agctggaagc ggtaaagcat tattgataag aagcgtcata
     7981 agatatttca atttattcat atccttatga cgcttttgtg caagttttac atcctttgaa
     8041 aattgtcccg agtattcaat atccctttga atcatattta aattcctaat ttatcaaata
     8101 aatcatcggc gtctttggcc ttatgaacat caacgccagc ttcgctgttt ttgattgatt
     8161 gaatggttaa ttgattaggc tcgcgtaaat caaacggcaa tgccttttca cgcgcgacct
     8221 ttgtgagggt tatgcgaacc aggtcagaga tggtcagccc catcccggcc agtacgtccg
     8281 ccgcctgatt cttcagatct tcatcgattc gggcgcgaac aaatgcgtta gcagccattg
     8341 gggtatctcc tgtgctgtat atttattcag cttgaattgt agctcaaatg agcaacagcg
     8401 acaatccatg agtaatttaa taaacggatg tctttacata attaactgaa atatatttat
     8461 taattttata ataatggttt attaagtttg ttcaggtacg ggccgggata cactgcaaca
     8521 tcaatgcatg atcagccatt attgagtatg tccttgccgt cgattccctc ttttgtgttg
     8581 tcgggattac tgttgctttg cttgccgttt tcttcatttg ccagcgccac cacatcacat
     8641 atcactttca gctacgccgc ccgccagcgg atgcaaaatc gtgcgcgttt attaaaacag
     8701 taccaaaccc atctgaaaaa acaggccagc tatattgtgg aaggcaatgc cgaaagcaga
     8761 agggcgctac gccagcacaa ccgcgaacag ataaaacagc atccagaatg gtttcctgcg
     8821 ccgctcaagg cgagtgacag acgctggcag gcgctggcgg aaaacaacca tttcttaagc
     8881 agcgaccatc tgcataacat caccgaagtg gcgattcacc gtctggagca acagcttggc
     8941 aagccttacg tctggggcgg tacgcggccc gatcaaggct tcgactgtag cgggttagtt
     9001 ttttatgcct acaacaagat ccttgaggcg aaactcccac gcacggctaa tgagatgtat
     9061 cactatcgcc gggcaaccat tgtggcgaat aacgacctgc gccggggaga tttgctattt
     9121 ttccatatcc acagccgcga gattgccgac catatggggg tgtatctggg cgacggtcag
     9181 tttattgagt caccgcgcac cggggaaacc attcgggtaa gtcggttagc tgaacctttc
     9241 tggcaggatc actttttagg cgcgcggcgg atattgacgg aagagacgat tttgtaaatg
     9301 ggtaatattg acgaactggc aaaaggtcgg atgccacgcg gcatccgacc tgtttacatc
     9361 tgggctgaaa actcacgttc taagacatca acaatgagct ggttttttga aatggaatgt
     9421 tgtctggcga cgatggtcag ccgcgaatca atgtgatgag gaacacgaag cgtcaggcgt
     9481 ttttgctctt cttcttcacg aaaaggggca ataccgtcct cttcacaatc cgccatccac
     9541 tcatccagcg cgctttcgcc ttcacgatat aatgcctcaa tacttgtggc tacaaagtca
     9601 caataaccgt ttacattgag gaacttgccg cgaaatgcgt tgatatcggc ttcaaatgtc
     9661 actgcggctg gttgaccttt aattgtgata atgttcgatg ctttattcat aatctacccc
     9721 tacacagtta acaaaccact ccttaagacc tgctactgcg cctttatcca tcacattctt
     9781 tggatgtggc tcatgtgtgc tgaatttggt cgttccaatc tgaaattttc gtctggagcc
     9841 gttgttattt tttattgttc cacccacagc tttaatgagt gcaacaacat catcccattt
     9901 aattccagat tttggcggct ccgtcattac atcgtcgaat gtttttctat gacgagaacc
     9961 tagcgcgctg accttaatca tactatcaat ccatgacgtc attgtatggt gtcatcgtag
    10021 tctctttgca gtgtgacgtc aattaatggt gtcaggtgct gcaaagcatg gaaaagaatc
    10081 ccccatcaac tcaacgcccc cataatcttc aactccagct catccggcac ttcgttatac
    10141 gacagcacat gcagccccgg cgcaaacaac cttgcataac gcgccagcaa agggcgcagc
    10201 tgcggtggca ccagcagcac cgggtctttc cccgccgctt tcatctgctc tttcacctgt
    10261 ggcatcgtgc tctggaactg gttgagcata ttcgggtcca ctggcacgct gtcgagcatc
    10321 actttaccgc cctgttgcgc ctgattcact aggttagtca gcagattttc cagctcatta
    10381 ttcagggtat acaccgtcag ctcctgcttg cgaacgaacg gatgggtaat gctgcgccgc
    10441 agcgccaggc gcacatcggc tgccagcaga atatgatctt tggtcaccgc gctactggcg
    10501 accagcacgg tggcgatggt gacgatatcg cgcagggaaa cgccttcggt cagcagcgcc
    10561 cggtacactt tcagcaactg gctgtaattg agcaccgcgc ttaaatcctc cgccaggcgc
    10621 ggtgccatcg acgccaaacg gttatgcaac tgcgtaatat cgtcatagtt aaataaatca
    10681 ggaatatagc tgcgcacaat cttatttaca tgggtagcaa tcacgctggc gctgtcgatc
    10741 acctgatacc ccatattcag cgccttcgct ttctgcgcag gctggatcca ggtcaccggc
    10801 atcccgtacg ccgggtcgtt ccccagcacg ccgtctatct cgccgtaggt ttcgctggag
    10861 ggcagcgcca tcagtttatc cgccggaata tccgcttcat cagccttaat gccgttgatg
    10921 aaaatagcgt actggctggg cttaaggcgg aagttttccc gaatgcggat ctccggcagc
    10981 agcacgccgt tgccgtcgga tatcacctgt cgcacgccgc gaatacgctg ggtgagcggg
    11041 ttgccctggg ctttgtccac cagcgccacc agcttgtagc cgaggcttaa gctgatgggc
    11101 tcgatcagcg gaatggtttc ccaactgacc tgttgctcgc tggtttcggt gatggtgcgg
    11161 gtcagcgttt cgagactttt ctcttccgct tccgccgcct gcgggcgttt gctcatccgc
    11221 cagccggtaa agccaagcag ggcgctgaac agcaaaaacg gcagatgtgg cattcccggc
    11281 actaccgcca gtacgaacat aattccggta gcggtgtaga gcaccgatgg gcttgccagc
    11341 aactggttac gcacgtcatg ggcgatatcg ccgttgtcgc tgacgcgggt gacgataatc
    11401 gccgccgcgg tggagagtag cagggaaggg atttgcgcca ccagcccgtc gccgatggtc
    11461 atcagcacat actgctggaa ggcggcgtcg gcgctcaggt tgtatttgaa gatcccgata
    11521 cagacgccgc cgatcaggtt gatcgccaga atcatcatac cggcgatagc atccccgcgc
    11581 acaaatttcg atgccccgtc catcgcgccg tagaaatcgg cctcgctggc aacatcttta
    11641 cgtcgggttt gtgcctgcgc ctgattgatc aacccggcat taagatcggc gtcaatcgcc
    11701 atctgcttac cgggcatcgc gtccagggta aagcgggcag aaacctcgga gatacgctcg
    11761 gcccctttgg tgacgacaat aaagttgatt gtcaacagcg tcagtaaatc cgagcgtgaa
    11821 agcattatcg ccgcgctgca cgggcagtcg atttttaacg gtggtgggct gtcgccgtta
    11881 aataaaatca gcccgtctca tccgccaaaa cctgccaccg tggcggtgcc ggaagaaacg
    11941 gagaaaaaag cgcgcgacgt caatgagaaa acggcgctgc tgaagaagaa atccgccacc
    12001 gagcttggcg agctggcaac cagtatcacc accattgccc gtgatgcgca tatggaagcg
    12061 aatctggaga tggagattgt tccccaggga ttacgcgtgc tgattaaaga cgaccagaat
    12121 cgcaatatgt tcgaacgcgg cagcgcgcag attatgccgt tctttaaaac gctgctggtg
    12181 gagctcgcgc cagttttcga ctcgctcgat aacaaaatta ttattaccgg gcataccgat
    12241 gcgatggctt acaaaaacaa tatctacaac aactggaacc tttcgggtga ccgcgcgctt
    12301 tcggctcgtc gggtgctgga agaggccgga atgccggaag ataaagtgat gcaggtaagc
    12361 gcaatggcgg accagatgct gctggattcc aaaaatccga aaagcgcggg caaccggcgc
    12421 attgagatta tggtgctgac caaaagtgcg tccgatacgc tgtatcaata ctttggtcag
    12481 catggggata aagtggtgca gccgctggtg caaaagctgg ataagcagca ggtgctttcg
    12541 cagcgaacgc gttaaatgct gaatctttac gcatttctca aaccctgaaa tcactgtata
    12601 ctttaccagt gttgagaggt gagtaatgcg taaaatcatt catgtggata tggactgctt
    12661 tttcgcagcg gtggagatgc gcgacaatcc cgccctgcgc gatatcccta ttgctattgg
    12721 cggcagccgc gaacgtcggg gggtgatcag caccgccaat tatcccgcgc gtaaatttgg
    12781 cgtacgtagc gctatgccga cagggatggc gctcaaatta tgcccgcatc tcaccttgct
    12841 tccggggcgc tttgacgcct acaaagaagc ctcaaatcat atccgtgaaa tcttctcgcg
    12901 ctacacctcg cgtattgaac cgttgtcact ggatgaggct tatctcgacg tcaccgatag
    12961 cgtccattgc cacggttctg cgaccctcat cgcccaggaa atccgccaga cgattttcag
    13021 cgagctgcaa ctgacagcgt ctgcgggcgt ggcaccagta aagtttctcg ccaaaatcgc
    13081 ctccgacatg aataaaccca acggtcagtt tgtgattacg ccggcagaag ttccggcatt
    13141 tttacaaacc ttaccgctgg caaaaatccc cggcgtcggc aaagtctcgg cggcaaaact
    13201 ggaagcgatg gggctgcgga cctgcggtga tgtacaaaag tgtgatctgg tgatgctgct
    13261 taaacgcttt ggcaaatttg gccgcatttt gtgggagcgt agtcagggga ttgacgagcg
    13321 cgacgttaac agcgaacggt tgcgaaaatc cgtcggcgtg gaacgcacga tggcggaaga
    13381 tatccaccac tggtctgaat gtgaagcgat tatcgagcgg ctgtatccgg aacttgaacg
    13441 ccgtctggca aaggtaaaac ctgatttact gattgcccgc cagggggtga aattaaagtt
    13501 cgacgatttt cagcaaacca ctcaggagca cgtctggccg cggctgaata aagctgactt
    13561 aatcgccacc gcgcgtaaaa cctgggatga acgccgcggc gggcgcggtg tgcgactggt
    13621 ggggctgcat gtgacgttgc ttgacccgca aatggaaaga caactggtgc tgggattatg
    13681 aataacatac aaataagaga ctatcagcct ggcgattttc agcaactatg cgctattttc
    13741 attagagcgg ttacgatgac tgccagtcag cattattcac cacaacaaat tgccgcctgg
    13801 gcgcagattg acgaatctcg ctggaaggag aaactcgcga aatcacaagt gcgggttgca
    13861 gtcattaatg caaaactggt cggctttatt acctgcgttg aacactatat cgatatgtta
    13921 tttgttgacc ctgaatacac ccgccgtggg gttgccagcg ctttgttaaa acctttgatt
    13981 aagtctgaat ccgaacttac ggtggacgca agcataaccg caaaaccctt ttttgaacgt
    14041 tatggttttc agacagttaa gcagcaacgc gttgaatgtc ggggagagtg gtttattaat
    14101 ttttatatgc gttataaaca gcaacattaa atccagcttg caatgaaaat aacgcaagcc
    14161 tagtatgtgc gcgttttctt attccacaaa ctgcaaggag gtaaatcatg acaaatcctt
    14221 tatcaatgac tctttgcaga cctttccagg attaattctt tttttcttgc cctggattcg
    14281 tctgccattt cctgattttt taattgttac tctcaataat tcaagtcgca acacatgcaa
    14341 cttgaagtat gacgagtcca tttacggaat ggtatatggg caattatatt cgtcccttat
    14401 ccgatgcggt atttaccatc gcatctgatg acctgtggat cgagagttta gcgatccaac
    14461 aattacacac cacggcaaat ttacccaaca tgcagcgcgt agtggggatg ccagatttac
    14521 atcccggacg cggctatccg attggcgcag cgttcttctc tgttggtcgt ttttatccgg
    14581 cactggtcgg caatgatatc ggctgcggta tggcgctatg gcaaacagat attctcgctc
    14641 gcaaatacaa cgccgataag tttgaaaagc gattatcaga tctggatgac gttgctgaag
    14701 aaagctggct ggaggaaaac ctgccgtcag catttgcaca gcatccgtgg cgcagctcgc
    14761 ttggctctat cggtggcggc aatcatttcg ctgaactgca acaagttgat caaatcatca
    14821 acgctgaact gtttgcactg gcaggtctgg atgcacaaca tctgcaactg ttggttcata
    14881 gcggctcgcg gggggtgggg cagtctattt tacagcggca tattgcctcg ttctcgcatc
    14941 atggtttgcc tcaaggcagt gacgacgcgc tacggtatat tgcggaacat gacgatgcgc
    15001 tggcgtttgc gtgtattaat cgccagatga tcgctttgcg cataatgcaa caagttaagg
    15061 ccacgggaag tccggttctg gatgtggcgc ataactttgt tagcgcgtgt caaatcggcg
    15121 agcaacaggg ctggttgcat cgtaaaggtg ccacgccgga tgacaacggt ctggtgatta
    15181 ttcccggttc acgtggtgat tactcctgga ttgtacagcc tgttgcgaac gaaaaaacgc
    15241 tccactcgct ggcgcatggg gcagggcgta aatgggggcg caccgagtgt aaagggcgtc
    15301 tggcagcgaa atacacggcg acgcaactct cgcgtactga acttggcagt cgggtaattt
    15361 gtcgcgataa acaactcatc tttgaagaag cgccacaagc ctataaatcg gctgaaagcg
    15421 tggtgcaatg tctggtgcag gccggtttaa ttattcctgt cgcgcggctg cgtccggtgc
    15481 taacgctcaa aaacagtgga gggaaaaaag gatgatcttg ctacaactct cctcagcgca
    15541 ggggccggaa gaatgttgtc tcgcagtgaa aaaggcgctg gacaggctta ttaaagaagc
    15601 tgcccgacaa gacgtcgcgg taacggtgtt ggaaacagaa acgggccgct actctgacac
    15661 gctgcgttcg gcgctgattt ctctggatgg cgataacgca tgggcattaa gcgaaagctg
    15721 gtgtggcgct attcagtgga tttgtccgag tccgtatcgg cctcatcatg ggcgcaaaaa
    15781 ctggtttctg ggcattgggc gttttaccgc tgatgagcag gaacaatcgg atgcaatccg
    15841 ttatgagacg ttgcgttcgt cggggccggg cggtcaacat gtcaataaaa ccgactcggc
    15901 ggtacgcgcc acgcatttgg catccggtat tagcgtgaag gttcagtcag agcgtagtca
    15961 gcatgctaac aagcggctgg cacgattgct gattgcctgg aagctggagc agcagcaaca
    16021 ggaaaatagc gcggtgctga aatcgcagcg gcgaatgttc catcaccaga ttgaacgtgg
    16081 caacccgaga cggacattta cagggatggc ttttatcgaa ggataatgaa ggatgaaact
    16141 gccggaaggc gattaaacgc catccggcag caaatcaaat aattacttcg ccggaatttc
    16201 tttcagcagt tcagtcagca gcgtccagta atgacctacg ctttcgatgt gaacttgctc
    16261 atccggagag tgtggaccgg tgatagttgg cccgatagaa accatgtcca tttccggata
    16321 cggttttttg aacagaccac attccaggcc cgcgtggata atctggatgt tcggtgtttt
    16381 gttgaacaga cgctgatagg tttcacgtac cagatgcatc accggagaat tagcgtccgg
    16441 ctgccagcca ggatatgcgc ctttcgcttc ggttttcgcg ccagccagtt tacccagcga
    16501 atccagcatg ctcacgacgt agtctttacc gctgtcgatc agtgaacgga tcagacagtg
    16561 aatttctacg ttattatcag tcatggtcac cacaccgacg ttcagggagg tttcgaccac
    16621 accttttgcc acgtctgagt tgcggatcac accgttcggg gtggcgttca gcagacgaat
    16681 aaaggtatcg cgagatttcg caatcagggc agctttatcg ttcgctacag agtccagcaa
    16741 caaggccaga tttttctctt tctctgccag ctcgtttttc aggatctcct gataggtatt
    16801 catcagagat ttcaggacgt cgactttatc agctgcgaca gcaatggtcg caaaggcttc
    16861 acgcgggatg gcgttacgca gtgtgccgcc gttgaaatcg ataaggcgca gatccagttc
    16921 ttctgcatga cccgccagga agcgcaccag cagtttgttg gcattaccca ggccaacgtg
    16981 gatttccccg ccggagtgac cccctttcag accttttaag gttaacttga aggtttcaaa
    17041 accagctgga accgcttcac gatctaaatg caggttggag gtgaagtcga taccccccgc
    17101 acaacccatg tagatttcac cttcttcttc ggagtcggtg ttaatcagaa tatcagcctg
    17161 caaccagttg ctctgtaagc cgaacgcacc gtccataccg gcttcttcgg tcatggtcag
    17221 cagcacttcc agcgggccgt gaaccacgtt ttcgtcagcc agaactgcca gtgcagaggc
    17281 cataccaatg ccgttatccg cacccagcgt ggtgccgcgc gctttaaccc attcgccatc
    17341 aatataaggc tggataggat ctttcgtgaa gtcatgcacg gtgtcgttat ttttctgcgg
    17401 caccatatcg aggtgggcct gtaagacgac cggtttacga ttttccatac ctgcggtagc
    17461 aggtttacga atcaggatat tacctacctg atcgcgttcg acatggaaac ctttctcttt
    17521 tgcccaacca acaatgtatt cagcgagttg ctcttcatga taggacgggt gaggaataga
    17581 acagattttg gcaaaaatat cccacagcgg ctgtggagat aattgagaca gttcagacac
    17641 gttaagtctc cttgtcgatc acccgcaaaa cagtattgca ggtcacaggg ttagcagaaa
    17701 atgttgtcaa cacaagacag gcttgcgaga tatgtttgag aataccactt tatcccgcgt
    17761 cagggagagg cagtgcgtaa aaagacgcgg actcatgtga aatactggtt tttagtgcgc
    17821 cagatctcta taatctcgcg caacctattt tcccctcgaa cactttttaa gccgtagata
    17881 aacaggctgg gacacttcac atgagcgaaa aatacatcgt cacctgggac atgttgcaga
    17941 tccatgcacg taaactcgca agccgactga tgccttctga acaatggaaa ggcattattg
    18001 ccgtaagccg tggcggtctg gtaccgggtg cgttactggc gcgtgaactg ggtattcgtc
    18061 atgtcgatac cgtttgtatt tccagctacg atcacgacaa ccagcgcgag cttaaagtgc
    18121 tgaaacgtgc agaaggcgat ggcgaaggct tcatcgttat tgatgacctg gtggataccg
    18181 gtggtactgc ggttgcgatt cgtgaaatgt atccaaaagc gcactttgtc accatcttcg
    18241 caaaaccggc cggtcgcccg ctggttgatg attatgttgt tgatatcccg caagatacct
    18301 ggatcgaaca gccgtgggat atgggcgtcg tattcgtccc gccaatctcc ggtcgctaat
    18361 cttttcaacg cctggcactg ccgggcgttg ttctttttaa cttcaggcgg gttacaatag
    18421 tttccagtaa gtattctgga ggctgcatcc atgacacagg caaacctgag cgaaaccctg
    18481 ttcaaacccc gctttaaaca tcctgaaacc tcgacgctag tccgccgctt taatcacggc
    18541 gcacaaccgc ctgtgcagtc ggctcttgat ggtaaaacca tccctcactg gtatcgcatg
    18601 attaaccgtc tgatgtggat ctggcgcggt attgacccac gtgaaatcct cgacgtccag
    18661 gcacgtattg tgatgagcga tgctgaacgt accgacgatg atttatacga tactgtgatt
    18721 ggctaccgtg gtggcaactg gatttatgag tgggccaccc aggcgatggt gtggcaacaa
    18781 aaagcctgtg cggaagaaga tccgcaactc agtggtcgac actggctgca tgcggctacg
    18841 ttgtacaaca ttgccgccta tcctcatctg aaaggagatg acctggccga gcaagcgcag
    18901 gctttatcaa accgcgccta tgaagaggcc gcccagcgtc tgccgggcac gatgcggcag
    18961 atggagttta ccgtacccgg cggtgcgccc atcaccggct ttttgcatat gccgaaaggc
    19021 gatggcccgt tcccgacagt attaatgtgt ggtggtctgg atgcgatgca gacggactat
    19081 tacagcctgt atgaacgtta ttttgcgccg cgcggcattg cgatgctgac tattgatatg
    19141 ccgtcggtgg gcttttcttc aaaatggaag ctcacccagg actccagcct gttgcatcag
    19201 cacgtcttaa aggcgctgcc taacgtaccg tgggtggatc acactcgcgt cgcggccttt
    19261 ggtttccgtt tcggcgctaa cgttgccgtg cgtctggcat accttgaatc gccgcgtctg
    19321 aaagcggttg cctgtcttgg tccggtagtt cataccctgt tgagtgattt taagtgccag
    19381 caacaggtgc cggaaatgta tcttgacgtt ctggcgagtc gtttggggat gcatgatgct
    19441 tccgatgacg cgttgcgcgt ggagctgaat cgctattcat taaaagtgca aggattgctg
    19501 ggacgtcgct gcccaacgcc aatgttatca ggctactgga agaacgatcc gttcagcccg
    19561 gaagaggact cacgcttaat cacctcatca tctgctgacg gtaaattatt agagatccca
    19621 tttaacccgg tgtatcggaa ttttgacaaa ggtcttcagg aaatcaccgg ctggatcgaa
    19681 aaacgcttgt gttaaaaatt tgctaaattt tgccaatttg gtaaaacagt tgcatcacaa
    19741 caggagatag caatgacgtt accgagtgga cacccgaaga gcagattgat caaaaaattt
    19801 accgcactag gcccgtatat tcgtgaaggt aagtgcgaag ataatcgatt ctttttcgat
    19861 tgtctggctg tatgcgtcaa cgtgaaaccg gcaccggaag tgcgtgaatt ctggggctgg
    19921 tggatggagc tggaagcgca ggaatcccgt tttacctaca gctaccagtt tggtctgttc
    19981 gataaagcag gcgactggaa gagcgttccg gtaaaagaca ctgaagtggt tgaacgactg
    20041 gagcacaccc tgcgtgagtt tcacgagaag ctgcgtgaac tgctgacgac gctgaatctg
    20101 aagctggaac cggcggatga ttttcgtgac gagccggtga agttaacggc gtgagtgaaa
    20161 tgtgccggat gcatcacatc cggcaataat cattaaaact gataggtcat gccaaccgcg
    20221 acaatatcat cattattaat attcaatttg ttatcgctat ccagttggtt gattttataa
    20281 tcaacaaacg ctgacatatt tttgttgaaa taatatgtag ccccgacatc gatataattg
    20341 accagatctt catcaccgat accttcaata tctttccctt tcgataagac ataacccagc
    20401 gatggacgca gaccaaagtc aaactggtat tgagcgaccg cttcaaagtt ctgtgtctta
    20461 ttggcaaagc cgccagttat tggcgtcatt ttgcgtgttt cagaataaaa agttgccaga
    20521 taaatattat tggcatcgta tttcagacct gttgcccatg cttctgcacg cttgccagtg
    20581 ccacggcttt gcaggttctg ctcgttggtg cgatctgagt tggtataggc accactaatg
    20641 gcgaaatcgc tgccgccaaa gtcatatgtc aatgacgtgc cgaagccatc gccgttttgc
    20701 tttttaacgt cgcggttttc gtttttccct tgatattgca gggttaagtt caggccatcg
    20761 ataacgccga agaagtcggt gttccgatac gtcgccagac cgctggcgcg tttggtcata
    20821 aagttgtcgg tctgcgccga ggagtcgcca ccaaattccg ggaacatatc ggtccaggct
    20881 tccacgtcat acaacgcgcc caggttacgg ccatagtcga aagaacccaa atctttatac
    20941 ttcaatccgg caaaagcgag acgcgttttt tgctgtgcag tatcactctc cgctttattt
    21001 ccggcaaact ccgcttccca acggccatag ccagtcagtt gatcgttaat ttgtgtttcg
    21061 cctttaaaac caaaacggat ataactctgg tcgccatctt tactgtcgtt atcactcata
    21121 taatgcatgg ctttaacttt gccatagaca tccagtttat taccgtcttt gttatatatt
    21181 tctgcggcct gtacggatgc agatgccaca atgcccatca ccactaatgc cagagtgctc
    21241 tttttcattt tcattcctga ttttaattaa cgcgcgaata ttcagcggga gagccccgtt
    21301 gaaaacagga aagtttttaa cctgagattg ttaaagatat attacagatt aataatattc
    21361 ttaaaatgtg gtaatttatt aaatctgtaa taaaagcgta aacaactgcc gctaggcttg
    21421 ctgatcccgc gcaacaaaac gccatgcttt gcttgcagat ggttggcaac cgacgacagt
    21481 cctgctaaaa cgttcgtttg atatcatttt tcctaaaatt gaatggcaga gaatcatgag
    21541 tgacagccag acgctggtgg taaaactcgg caccagtgtg ctaacaggcg gatcgcgccg
    21601 tctgaaccgt gcccatatcg ttgaacttgt tcgccagtgc gcgcagttac atgccgccgg
    21661 gcatcggatt gttattgtga cgtcgggcgc gatcgccgcc ggacgtgagc acctggggta
    21721 cccggaactg ccagcgacta tcgcctcgaa acaactgctg gcggcggtag ggcagagtcg
    21781 actgattcaa ctgtgggaac agctgttttc gatttatggc attcacgtcg ggcagatgct
    21841 gctgacccgt gctgatatgg aagaccgtga acgcttcctg aacgcccgcg acaccctgcg
    21901 tgcgttgctc gataacaata tcgttccggt aatcaatgag aacgatgctg tcgctacggc
    21961 agagattaag gtcggcgata acgataacct ttctgcgctg gcggcgattc tggcgggtgc
    22021 cgataaactg ttgctgctga ccgatcaaaa aggtttgtat accgctgatc cgcgcagcaa
    22081 tccgcaggca gaactgatta aagatgttta cggcattgat gacgcactgc gcgcgattgc
    22141 cggtgacagc gtttcaggcc tcggaactgg cggcatgagt accaaattgc aggccgctga
    22201 cgtggcttgc cgtgcgggta tcgacaccat tattgccgcg ggcagcaagc cgggcgttat
    22261 tggtgatgtg atggaaggca tttccgtcgg tacgctgttc catgcccagg cgactccgct
    22321 tgaaaaccgt aaacgctgga ttttcggtgc gccgccggcg ggtgaaatca cggtagatga
    22381 aggggcaact gccgccattc ttgaacgcgg cagctccctg ttgccgaaag gcattaaaag
    22441 cgtgactggc aatttctcgc gtggtgaagt catccgcatt tgcaacctcg aaggtcgcga
    22501 tatcgcccac ggcgtcagtc gttacaacag cgatgcatta cgccgtattg ccgggcacca
    22561 ctcgcaagaa attgatgcaa tactgggata tgaatacggc ccggttgccg ttcaccgtga
    22621 tgacatgatt acccgttaag gagcaggctg atgctggaac aaatgggcat tgccgcgaag
    22681 caagcctcgt ataaattagc gcaactctcc agccgcgaaa aaaatcgcgt gctggaaaaa
    22741 atcgccgatg aactggaagc acaaagcgaa atcatcctca acgctaacgc ccaggatgtt
    22801 gctgacgcgc gtgccaatgg ccttggcgaa gcgatgcttg accgtctggc actgacgccc
    22861 gcacggctga aaggcattgc cgatgatgtg cgccaggtgt gtaacctcgc cgatccggtg
    22921 gggcaggtaa tcgatggcag cgtactggac agcggcctgc gtcttgagcg tcgtcgcgta
    22981 ccgctggggg ttattggcgt gatttatgaa gcgcgcccga acgtgacggt tgatgtcgct
    23041 tcgctgtgcc tgaaaaccgg taatgcggtg atcctgcgcg gtggcaaaga aacgtgtcgc
    23101 actaacgctg caacggtggc ggtgattcag gacgccctga aatcctgcgg cttaccggcg
    23161 ggtgccgtgc aggcgattga taatcctgac cgtgcgctgg tcagtgaaat gctgcgtatg
    23221 gataaataca tcgacatgct gatcccgcgt ggtggcgctg gtttgcataa actgtgccgt
    23281 gaacagtcga caatcccggt gatcacaggt ggtataggcg tatgccatat ttacgttgat
    23341 gaaagtgtag agatcgctga agcattaaaa gtgatcgtca acgcgaaaac tcagcgtccg
    23401 agcacatgta atacggttga aacgttgctg gtgaataaaa acatcgccga tagcttcctg
    23461 cccgcattaa gcaaacaaat ggcggaaagc ggcgtgacat tacacgcaga tgcagctgca
    23521 ctggcgcagt tgcaggcagg ccctgcgaag gtggttgctg ttaaagccga agagtatgac
    23581 gatgagtttc tgtcattaga tttgaacgtc aaaatcgtca gcgatcttga cgatgccatc
    23641 gcccatattc gtgaacacgg cacacaacac tccgatgcga tcctgacccg cgatatgcgc
    23701 aacgcccagc gttttgttaa cgaagtggat tcgtccgctg tttacgttaa cgcctctacg
    23761 cgttttaccg acggcggcca gtttggtctg ggtgcggaag tggcggtaag cacacaaaaa
    23821 ctccacgcgc gtggcccaat ggggctggaa gcactgacca cttacaagtg gatcggcatt
    23881 ggtgattaca ccattcgtgc gtaaataaaa ccgggtgatg caaaagtagc catttgattc
    23941 acaaggccat tgacgcatcg cccggttagt tttaaccttg tccaccgtga ttcacgttcg
    24001 tgaacatgtc ctttcagggc cgatatagct cagttggtag agcagcgcat tcgtaatgcg
    24061 aaggtcgtag gttcgactcc tattatcggc accattaaaa tcaaagagtt accccatatt
    24121 taaatacacc acgtttcctc ctgtgccgca tttgtgccat tgtaaccttg gcaattcatc
    24181 aaaatactgt tctgacatca ggcagtgcag gtgcagctat ttaaaccaat tgctgccgcc
    24241 attctttgac gtagtcaatc agggcgcgga gctttggtgc aatattgcga cgctgtggga
    24301 aatacagata gaagcccgga aattgtggaa gaaagtcatc aagcagcgat acaagcttac
    24361 cgctttcaat atatggcctg aaagtttcct gagtggcaat tgttattcct ccgccggcaa
    24421 gagccagcct caacatcaga cgcagatcat tagtcgtaat ctgcggttca atcgcaaggt
    24481 cgaaagttct cccgttttct tcaaatggcc agcgataagg cgcaacctcc ggggactgac
    24541 gccagccgat acacttatgg gtatttcccc cggaggcgag aaagcgctct ccacgcccgg
    24601 ccgcaaggat caggacgacg ggggcaggca tgaatcctcc tcctgatgga gacgtacaga
    24661 ggcgacttct gccagcacgg agagtgccag agtatgcgca tcccgggctt tggggaatat
    24721 cccgacgggt gcccggattt gcgttgtttc ctccctggac catcccagct cgtggagctt
    24781 ttgcagacgt aacgtgtggg ttcgatagct gcccaatgcg ccgagataaa agggttttgc
    24841 ttctcgcgcg gcctgcaaca ctggcagctc ccggttgaga tcatggcaca gcaaaatgac
    24901 cgccgtatcg gtatcgatct gagcgctggc tgaggccgga aaaagatcga agatatggct
    24961 gtcatagcct gtggctgctg caagactcgc agttgcctgc gtctcaagag aacgtccgta
    25021 aatcatcagc ctgacgcatg gcctgaaccc cacctcaaag ccattgagat tccagcccgt
    25081 tcgggtttgc gtgggcaggc acaccagcga ttgtgcttgc ggatcgtagc gcagccccgc
    25141 cggttttctc tgttccagac ggttcagcac ggcgagcaga ggctgtgccg agcgtagttt
    25201 atggagcgtc agcgtgatcc caccgccgca gggcagaacg atgtcaaacc acggcgaacc
    25261 ttcgccatag cgaatttcgc gatcgcggcc tgagcccatc atctccagcg cttcaaaagc
    25321 ggcagcggcc tccacgcagc cgccagagac aaaaccgcag taacgaccat cttcgcgaac
    25381 caccatctgc gccccgagcg ggcgcgctgc gccgccgcgt atctccacca gcgtcaccag
    25441 caccgctcct ttaccggaca ttagcgcctc tacggcgaag cgcagaatgg tccggtggtc
    25501 atcggtgaga aacgcctgct ctggcttatg ccagtgttcg tctttatcaa aaagcgggta
    25561 tgacattgtt tctccttaaa ccacatccgg cagcttatcg agcagcttat ccagagtgat
    25621 gggataatcc cgtacccgaa taccggtggc gttatacacc gcgttggcga tagccgcgct
    25681 cacgccgcac aggcccagct caccgacacc tttggccttc atcggggagg atatggggtc
    25741 ggtatcatcc aggaaaatca cctcctgttt tgggatatcc gcatggaccg gcacctcata
    25801 ccccgccata tcgtgattaa cgaagtagcc caaacggtca tccaccgcca gctcctccat
    25861 cagtgccgcg cccatgccca tagtcattgc gccaatgacc tggctgcgcg cagttttcgg
    25921 attcaggatg cgtcctgcag cacacacagc gagcatacgc cggacccgaa cttctcccgt
    25981 cgcgctatgc acgccgacct ccacaaaatg cccggcaaag gtcgactgct ggtactcttt
    26041 gctcagtgtt ccgaattcaa tgctctcttc cgctgtcagt ctgccgcctg cggtggcttc
    26101 atgtagcgtg gcgcttcggg taccgttggt aatcttgccg tcggcaaact gcgactgctc
    26161 aggatcaaac ccgactgccg aggcaatcat ttcgcgaagc ttcatacagg cggcgtaaac
    26221 gccggaggtg gaggtattcg cgccccattg tcctccagaa cccgcagaaa ccgggaaact
    26281 ggaatcgccg aggtgaaccg caacctgctc cagcggtacg ccaagcattt ccgctgccgt
    26341 ctgggccaga atggtgtagc tgccggtgcc aatgtcggtc atgtccgttt ctacggtaac
    26401 ggtgccgttt tgttcgaggt gaacccgagc acccgatttt tccagcagat tattgcgaaa
    26461 gcccgccgca acaccgtggc cgactagcca ctccccgtcg cgcacctgtc cgggtgtggc
    26521 gttgcgctgc ttccagccaa atttatccgc tccggtgcgc aagcactcga taagctgacg
    26581 gcgagagaag cagcgcgtcg ggtcggcggg gtcaacctga gtgtcattca ggatgcgaaa
    26641 ctcgacggga tcgatgcccg ctttttccgc cagttcgtcg atcgcgattt cgagcgccat
    26701 cagaccgggg gcttcgccgg gcgcacgcat ggcgttccct tccggcaaat caagcgtggc
    26761 gagccgcagg ccggtatgac gattcgcccc ggcgtagagt aattcgcttt gctgtaccgc
    26821 cgtttccggc gtgccgccgg gcaggtttcc agaccagctt tcatgtgaga tagcggtgat
    26881 tttcccgctc tggtcggcac cgatacgcaa gtgctgaagg gtggcggggc ggtgcgtggt
    26941 gttattggga atagaggggc gggggagcat cactttaacc ggacgtttca ccgctcgggc
    27001 ggcgagggcc gccagcagcg catcgcttct caggaacagc ttgccgccaa accctccgcc
    27061 gatatacggg gagataatac gcacattctc cacgggaact ttcagcgttt ttgccagatc
    27121 ggtgcggcac cagtcaatca tctgatttga ggtccagagg gtaagcttat ttccatccca
    27181 gacggccatc gaggcatgcg gctccatcgc catatggctc tggtccgggg tcgtgtaggt
    27241 agcatcaatc ttcaccgcag cggaggtgaa agccccgtca aagtcaccga cgtttttgtc
    27301 gggcgtgtct tccggcggct gattgacggc ctgtttttcg tccgccaggg agtaagctcc
    27361 tttattacgg cgatagtgtg cctgcaccag cgaggccgcc gctcgcgcct gttcgaaggt
    27421 ctcggccact accagcgcaa tggcctgatg atagtgctca atagtggggc cgcctaacag
    27481 tctggcggtg tttttgtcgc ctttgccgag tgccccggcg ttactggcgg taatgacagc
    27541 cagtacgccc ggcgcttttt gcgcggcgtc cgtatcaagg gcggtgaggc gtcctttggc
    27601 aatggcggaa ccgacgatat agccataggc ggcgttgggg gcttcttcat gccattcgta
    27661 ggcgtagcgt gccgtgccgg tagttttcag cggtccgtcg atgcggtcat ggggacgacc
    27721 gacaaccttc agctgatcga tcgggttttc ccctgcgggt ttatcaaatt tcatgcctgt
    27781 gccctcgctt cagccagtac ggaggcaagc gttcgcttcg ccaacaggag tttaaaggta
    27841 ttttcagcgg tgggatgggc gctggcgaac agcgcgtcat atacggcctg cgccccctgg
    27901 gatagctgag catccgcagc ctcaatgcgc cagggcttat gtgctactcc gcccagcgcg
    27961 acgcgcccgc tgccgtcagg ctgaataatc gccgcgaccg ataccagggc aaaggcgtag
    28021 gaggcgcgat cgcgcacctt acggtagata tgttttccgc cgagcggtgg aggtaacgtc
    28081 accgcaacga taagctcacc gggaagcagg gcggtttcaa tgtgcggcgt tttccccggt
    28141 gggtgataaa aatcagccag tgtgatactg cgagtctttc cctccggcgt gatggtttcc
    28201 accaccgcat ccagcaaccg cattgcgacc gccatatcgc tcggatgggt ggctatgcag
    28261 gcttcactta cgcctaccac cgcgtgctga cggctaaagc cttcaagcgc cgcgcagccg
    28321 ctcccgggca ggcgcttatt gcagggctga ttggtgtcgt aaaaataggg gcagcgcgtg
    28381 cgctggagca gattacctgc ggtggttgcc tgattacgta actgaccaga tgcgccagcg
    28441 agcagggcgc gggagagtac cgcgtaatca cgacgcacgc gctcgtgagc cgccaggtcg
    28501 gtgttccgta ccagtgcgcc gatgcgcagc ccacccgcgt cggtcacttc aatcttatcg
    28561 agcccgaggc cgttcacatc gataaggtgg gtgggcgttt caatttccag cttcatcagg
    28621 tccagcagat tggtcccgcc cgcgataaat tttgcgccgg gtacgcgctg agcgctaagt
    28681 gccgcctcgg ctggggtgtt cactcgttca taggtaaacg ccttcatgat tttatctccc
    28741 ccgcagcatc ttcaatggcg gcaaggatgt tagcgtatgc accacagcga cagatgttgc
    28801 cgctcatacg ttcacggatc tcatcggcag ttgtttctgg agcggaaacc aaatcgaccg
    28861 tgacgtgact gggaatgccg tcctgaatct cttttagcgc cgctactgat gagcaaattt
    28921 gcccggaggt gcagtagccg cactggaagc catcatgctt gataaaggcc gcctgcatgg
    28981 ggtgaagatt atctggcgaa cccaggcctt caatggtggt gatctcggcc ccctgatgca
    29041 tgactgcaag cgtcaggcag gcattaagcc tgcgaccatt gaccagcacg gtacaggctc
    29101 cgcactgtcc gtgatcgcaa cctttcttgg taccgatcaa atgcagattt tcacgcaaag
    29161 cgtccagtag cgtggttcgg gtatccacct caagctgctc ggttttgccg ttcaccttca
    29221 gtgtcagggg cattatctct ggcgcgggtg tagctgccgg aacgcttgcc gccagcgtag
    29281 aatgaggata aaccacggcg gtcgccgctg ttgcggcgct cactttaatc agatcgcgac
    29341 gggtcaaact taaatcgtgc ggctcgtgct tcccaacccg attatcttcg gggtattcgc
    29401 cttggttgct cataccaggc ctccggtatt ctaaagggga aaataagagt gcgttgcgag
    29461 agtgctgatg cttttttaaa tgttaagcat agtcggcgac agcaggagga ttattcttaa
    29521 aacgcgaatg cagctatgag cccggctaat aaattcatgt tcgccgggat gttgatgatg
    29581 atgggagctg gtttattgct ttagttgtac gatgcaaaaa ccaataagga aacctgtgat
    29641 tttcagctct gcatcaccct gcaaatctct gtcacttcta atataaaaat agggagaaat
    29701 gatggagctt atattcattg gcgattagga aaccatcttg ttatacaaaa caatacagtt
    29761 ctttacattt accttgtttt atgaatactc ctgaagaggt gtataacata atggtacaag
    29821 cagggtagat atgaatatat ttgaacaaac tccaccgaac cgcagacgtt atggtcttgc
    29881 tgcattcatt gggctgattg ctggcgttgt ttccgcattc gtgaagtggg gctgaagttc
    29941 cattgccgcc acgtagcccg gtggatatgt ttaatgcagc gtgtggcccg gaatcattaa
    30001 tcagggctgc aggccaaatt gattgctcgc gtaattttct caatccaccg tatatttttc
    30061 ttcgagactg gttggggctg acagatccca atgcggctgt ttataccttt gccgggcatg
    30121 tctttaactg ggttggtgtt acgcacatta tcttttcgat agtgtttgct gtcggttatt
    30181 gtgtggtcgc tgaagtattt ccaaaaatta aactctggca gggcttactg gcaggtgctt
    30241 tagcccaact ttttgttcat atgatttcat tccctctcat gggactgacg ccacctctgt
    30301 ttgatctccc gtggtatgag aatgtttctg aaatttttgg acatttagtc tggttctggt
    30361 ctattgaaat tattcgcaga gatttacgaa acagaattac tcatgagcca gaccctgaga
    30421 tccctttagg ctcaaacaga taatgcattg aatgataaaa atggcgcaaa tacagcgcca
    30481 tttttatagg ttaaaaacat tgctttttat attctgattc agatagtcag tgagtatatc
    30541 gcgctacttc aggatgatgt agatccgaag aacgctacag aagagaggca ttgttgctgg
    30601 caaatagaag
//
LOCUS       DAZUDJ010000060        30304 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.060, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000060 DAZUDJ010000000
VERSION     DAZUDJ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30304
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.060"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(11..259)
                     /gene="hybG"
                     /locus_tag="ACHY1N_003540"
     CDS             complement(11..259)
                     /gene="hybG"
                     /locus_tag="ACHY1N_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HFS4045770.1"
                     /translation="MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADL
                     LGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA"
     gene            complement(272..613)
                     /gene="hypA"
                     /locus_tag="ACHY1N_003541"
     CDS             complement(272..613)
                     /gene="hypA"
                     /locus_tag="ACHY1N_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008901 - ferredoxin hydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HFS4045771.1"
                     /translation="MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAV
                     RFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPICHGERLRVDTG
                     DSLIVKSIEVE"
     gene            complement(606..1094)
                     /gene="hybE"
                     /locus_tag="ACHY1N_003542"
     CDS             complement(606..1094)
                     /gene="hybE"
                     /locus_tag="ACHY1N_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HFS4045772.1"
                     /translation="MTEEIAGFQTSPKAQVQAAFEEIARRSMHDLSFLHPSMPVYVSD
                     FTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDGV
                     SQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVTNPDVPHAGRRALLFGRRSGE
                     NA"
     gene            complement(1087..1581)
                     /locus_tag="ACHY1N_003543"
     CDS             complement(1087..1581)
                     /locus_tag="ACHY1N_003543"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HFS4045773.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKSAPGTMMILRDEEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPRE
                     AIHD"
     gene            complement(1581..3284)
                     /gene="hybC"
                     /locus_tag="ACHY1N_003544"
     CDS             complement(1581..3284)
                     /gene="hybC"
                     /locus_tag="ACHY1N_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008901 - ferredoxin hydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HFS4045774.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNL
                     AVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRG
                     KGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHS
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRE
                     STQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNI
                     GKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            complement(3281..4459)
                     /gene="hybB"
                     /locus_tag="ACHY1N_003545"
     CDS             complement(3281..4459)
                     /gene="hybB"
                     /locus_tag="ACHY1N_003545"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HFS4045775.1"
                     /translation="MSHDPQPLGGKIISKPVMIFGPLIVICMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLKRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSLLTAF
                     IMGFSIVIFEGSLVQAGLRGNGPDEKSLFVKLTNTISVLLAIFIVLRFGELIYRDKLS
                     LAFAGDFYSVMFWIEVLLMLFPLVVLRVAKLRNDSRMLFLSALSALLGCATWRLTYSL
                     VAFNPGGGYAYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            complement(4449..5435)
                     /gene="hybA"
                     /locus_tag="ACHY1N_003546"
     CDS             complement(4449..5435)
                     /gene="hybA"
                     /locus_tag="ACHY1N_003546"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HFS4045776.1"
                     /translation="MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINFPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGVNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPK
                     LDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES"
     gene            complement(5438..6556)
                     /gene="hybO"
                     /locus_tag="ACHY1N_003547"
     CDS             complement(5438..6556)
                     /gene="hybO"
                     /locus_tag="ACHY1N_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HFS4045777.1"
                     /translation="MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVT
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSA
                     GAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            complement(6745..7032)
                     /gene="yghW"
                     /locus_tag="ACHY1N_003548"
     CDS             complement(6745..7032)
                     /gene="yghW"
                     /locus_tag="ACHY1N_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 family protein YghW"
                     /protein_id="HFS4045778.1"
                     /translation="MNNHFGKGLMAGLKATHADSAVNVTKFCADYKRGFVLGYSHRMY
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSCSTLRFFMAGYRLEN"
     gene            complement(7151..8038)
                     /gene="yghX"
                     /locus_tag="ACHY1N_003549"
     CDS             complement(7151..8038)
                     /gene="yghX"
                     /locus_tag="ACHY1N_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311911.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YghX family hydrolase"
                     /protein_id="HFS4045779.1"
                     /translation="MPRLTAKDFPQELLDYYDYYAHGKISKREFLNLAAKYAVGGMTA
                     LALFDLLKPNYALATQVEFTDPEIVAEYITYPSPNGHGEVRGYLVKPAKMSGKTPAVV
                     VVHENRGLNPYIEDVARRVAKAGYIALAPDGLSSVGGYPGNDDKGRELQQQVDPTKLM
                     NDFFAAIEFMQRYPQAAGKVGITGFCYGGGVSNAAAVAYPELACAVPFYGRQAPTADV
                     AKIEAPLLLHFAELDTRINEGWPAYEAALKANNKVYEAYIYPGVNHGFHNDSTPRYDK
                     SAADLAWQRTLKWFDKYLS"
     gene            8195..9235
                     /gene="gpr"
                     /locus_tag="ACHY1N_003550"
     CDS             8195..9235
                     /gene="gpr"
                     /locus_tag="ACHY1N_003550"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HFS4045780.1"
                     /translation="MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALES
                     QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDM
                     WPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
                     KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVG
                     CIAFTPLAQGLLTGKYLNGIPQDSRMYREGNKVRGLTPKMLTEANLNSLRLLNEMAQQ
                     RGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVQALNNLTFSTEELAQIDQHIAD
                     GELNLWQASSDK"
     gene            complement(9275..9769)
                     /locus_tag="ACHY1N_003551"
     CDS             complement(9275..9769)
                     /locus_tag="ACHY1N_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HFS4045781.1"
                     /translation="MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPN
                     IFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
     gene            9960..10844
                     /gene="yghA"
                     /locus_tag="ACHY1N_003552"
     CDS             9960..10844
                     /gene="yghA"
                     /locus_tag="ACHY1N_003552"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HFS4045782.1"
                     /translation="MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKA
                     VLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
                     VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(11116..11541)
                     /gene="exbD"
                     /locus_tag="ACHY1N_003553"
     CDS             complement(11116..11541)
                     /gene="exbD"
                     /locus_tag="ACHY1N_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HFS4045783.1"
                     /translation="MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDPVTDETMITALNALTEGKKDTTI
                     FFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK"
     gene            complement(11548..12282)
                     /gene="exbB"
                     /locus_tag="ACHY1N_003554"
     CDS             complement(11548..12282)
                     /gene="exbB"
                     /locus_tag="ACHY1N_003554"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HFS4045784.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFNQKRRLKREQQLLAEARSLNQANDIAADFGSKSLSLHLLNEAQNELELSEGSD
                     DNEGIKERTSFRLERRVAAVGRQMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNVFARQIGGFKAMLGDVAAQVLL
                     LQSRDLDLEASAAAHPVRVAQKLRAG"
     gene            12534..13721
                     /gene="metC"
                     /locus_tag="ACHY1N_003555"
     CDS             12534..13721
                     /gene="metC"
                     /locus_tag="ACHY1N_003555"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HFS4045785.1"
                     /translation="MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKH
                     ATRNHANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFVEQGD
                     HVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSIT
                     MEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDA
                     MIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEW
                     LAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLSNEELANYLDNFSLF
                     SMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFA
                     RIV"
     gene            13861..14520
                     /gene="yghB"
                     /locus_tag="ACHY1N_003556"
     CDS             13861..14520
                     /gene="yghB"
                     /locus_tag="ACHY1N_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family general envelope maintenance protein
                     YghB"
                     /protein_id="HFS4045786.1"
                     /translation="MAVIQDIIAALWQHDFAALADPHIVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLILAGALIAQGVMDFLPTIAILTAAASLGCWLSYIQGRWLGNTKTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLPNRRFQFFNWLS
                     GLLWVSVVTSFGYALSMIPFVKRHEDQVMTFLMILPIALLTAGLLGTLFVVIKKKYCN
                     A"
     gene            complement(14560..15459)
                     /gene="yqhC"
                     /locus_tag="ACHY1N_003557"
     CDS             complement(14560..15459)
                     /gene="yqhC"
                     /locus_tag="ACHY1N_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YqhC"
                     /protein_id="HFS4045787.1"
                     /translation="MKREEICRLLADKVNKLKNKENSLSELLPDVRLLYGETPFARTP
                     VMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTVPLPFECETYATSEVPLAGLRLN
                     VDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCAAERLLDVMERPLDARILG
                     KQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEAN
                     MSVSAFHHNFKSVTSTSPLQYLKNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSR
                     EFKRYFGVTPGEDAARMRAMQGN"
     gene            15653..16816
                     /gene="yqhD"
                     /locus_tag="ACHY1N_003558"
     CDS             15653..16816
                     /gene="yqhD"
                     /locus_tag="ACHY1N_003558"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:1990362 - butanol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFS4045788.1"
                     /translation="MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKT
                     GVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTK
                     FIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE
                     GILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIVLPALWNEKRETKRAKLLQYAERVWNITEGSDDERIDAAIAETRNFF
                     EQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR"
     gene            16921..17748
                     /gene="dkgA"
                     /locus_tag="ACHY1N_003559"
     CDS             16921..17748
                     /gene="dkgA"
                     /locus_tag="ACHY1N_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050580 - 2,5-didehydrogluconate reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
                     /protein_id="HFS4045789.1"
                     /translation="MANPTVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRS
                     IDTAAAYKNEEGVGKALKNASVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYID
                     LYLMHWPVPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQ
                     IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVI
                     RWHLDSGLVVIPKSVTPSRIVENFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQFGG"
     gene            17948..18874
                     /locus_tag="ACHY1N_003560"
     CDS             17948..18874
                     /locus_tag="ACHY1N_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HFS4045790.1"
                     /translation="MKIILLFLAALASFTVHAQPPSLTVEQTVRHIYQNYKSDATAPY
                     FGEIGERAITSARIQQALTLNDNLTLPGNIGWLDYDPVCDCQDFGDLVLESVAITQTD
                     ADHADAVVRFRIFKDDKEKTTQTLKMVAENGRWVIDDIVSNHGSVLQAVNSENEKTLA
                     ALASLQKEQPEAFVAELFEHIADYSWPWTWVVSDSYRQAVNAFYKTTFKTANNPDEDM
                     QIERQFIYDNPICFGEESLFSRVDEIRVLEKTADSARIHVRFTLTNGNNEEQELVLQR
                     REGKWEIADFIRPNSGSLLKQIEAKTAARLKQ"
     gene            18925..19182
                     /gene="yqhH"
                     /locus_tag="ACHY1N_003561"
     CDS             18925..19182
                     /gene="yqhH"
                     /locus_tag="ACHY1N_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YqhH"
                     /protein_id="HFS4045791.1"
                     /translation="MKTIFTVGAVVLATCLLSGCVNEQKVNQLASNVQTLNAKIARLE
                     QDMKALRPQIYAAKSEANRANTRLDAQDYFDCLRCLRMYAE"
     gene            complement(19225..21444)
                     /locus_tag="ACHY1N_003562"
     CDS             complement(19225..21444)
                     /locus_tag="ACHY1N_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HFS4045792.1"
                     /translation="MSSISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWSSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRRLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGEPISEIR
                     DVRNTAIIVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKA
                     VTVQPPRPKPWEKTYVLLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYKRVPHPAYGNARIPAYEMIRFSVNIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICPHMDTNHEPTINLYRRARDLKGIKKILIASGVRYDIAVEDPRYI
                     KELATHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDTYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKKHRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKIGYK
                     SEDVFVPKGDKQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGSRRDCLVPAPTIE
                     EMREARRQNRNTRPALTKHTPMATQRQTPATAKKASSTQSRPVNAGAKKRPKAAVGR"
     gene            complement(21555..22967)
                     /gene="ftsP"
                     /locus_tag="ACHY1N_003563"
     CDS             complement(21555..22967)
                     /gene="ftsP"
                     /locus_tag="ACHY1N_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HFS4045793.1"
                     /translation="MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRR
                     GQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMT
                     VAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRPLHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     SLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADE
                     PQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNS
                     QTLEMADRGSIGQLLVNPVP"
     gene            complement(23042..23779)
                     /gene="plsC"
                     /locus_tag="ACHY1N_003564"
                     /gene_synonym="parF"
     CDS             complement(23042..23779)
                     /gene="plsC"
                     /locus_tag="ACHY1N_003564"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HFS4045794.1"
                     /translation="MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELA
                     AHCRSIMEQKIAELDKEVAEREAAGKV"
     gene            complement(24012..26270)
                     /gene="parC"
                     /locus_tag="ACHY1N_003565"
     CDS             complement(24012..26270)
                     /gene="parC"
                     /locus_tag="ACHY1N_003565"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009340 - DNA topoisomerase IV complex
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFS4045795.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTE
                     AEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGI
                     LASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITL
                     PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARG
                     EDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEID
                     SPRRASSGDSEE"
     gene            complement(26816..27298)
                     /locus_tag="ACHY1N_003566"
     CDS             complement(26816..27298)
                     /locus_tag="ACHY1N_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFS4045796.1"
                     /translation="MTNLTLDVNIIDFPSIPVAMLPHRCSPELLNYSVAKFIMWRKET
                     GLSPVNQSQTFGVAWDDPATTAPEAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVA
                     RHVGELDDISHTIWGIIRHWLPASGEKMRKAPILFHYTNLAEGVTEQRLETDVYVPLA
                     "
     gene            complement(27351..27743)
                     /gene="ygiW"
                     /locus_tag="ACHY1N_003567"
     CDS             complement(27351..27743)
                     /gene="ygiW"
                     /locus_tag="ACHY1N_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB fold stress tolerance protein YgiW"
                     /protein_id="HFS4045797.1"
                     /translation="MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNG
                     SVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKDASGTINVDIDHKRWNGVTVTPK
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            27895..28554
                     /gene="qseB"
                     /locus_tag="ACHY1N_003568"
     CDS             27895..28554
                     /gene="qseB"
                     /locus_tag="ACHY1N_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum sensing response regulator transcription
                     factor QseB"
                     /protein_id="HFS4045798.1"
                     /translation="MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGQREPVLILTARDALEERVEGLRLGADDYLCKP
                     FALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
                     LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGE
                     K"
     gene            28551..29900
                     /gene="qseC"
                     /locus_tag="ACHY1N_003569"
     CDS             28551..29900
                     /gene="qseC"
                     /locus_tag="ACHY1N_003569"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_306641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quorum sensing histidine kinase QseC"
                     /protein_id="HFS4045799.1"
                     /translation="MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELF
                     DTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGHVDDDALTFAIFTHDGRMVLNDG
                     DNGEDIPYSYQREGFADGQLVGDKDQWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
                     AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRP
                     LVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKAL
                     LQLHYGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKID
                     VRLTLNAHGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVIDVTLNADNFIVRDNGPGV
                     TPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSW"
     gene            complement(29946..30278)
                     /locus_tag="ACHY1N_003570"
     CDS             complement(29946..30278)
                     /locus_tag="ACHY1N_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2645 family protein"
                     /protein_id="HFS4045800.1"
                     /translation="MLKHKIQTIFEALLYIMLTYWLIDAFFAFNKYDWMLESGDNICS
                     IPSVSGEDRILQAMIAAFFLLTPLIILILRKLFMREMFEFWVYVFSLGICLVCGWWLF
                     WGRFIFCY"
BASE COUNT         7484 a         8086 c         7648 g         7086 t
ORIGIN      
        1 aagctaatca tcacgcgctg gtaatgtcgt aatccatttg gcgcagtgcg tctaatgtgg
       61 ctttggcttc atcttcgtcg atgatgctca tggcaaatcc gacgtgtacc agcacccact
      121 ggcccagcag atcggcaggg ttaccttcac aaatcagggc gatattcacg tcgcgcttga
      181 taccacatac ttcaacctgc gcaagctggt gaatatcttc accgacagcc agcacctggc
      241 ctggaacgcc aatacacatt attaactccg gttattcaac ttcaatactt ttgacgatca
      301 gcgaatcgcc ggtatcgaca cgcaaccgct cgccatgaca gatcggacac tgcgcatcgt
      361 gctgatgaat ctccaccacc tggctgcaat cccagcacca ggcctgggcg ggtttataga
      421 cgatatgtaa atcgcaccct tgcgccaccg ttccgtggca gacaatttca aaactaaaac
      481 ggacggcgct ctcctcaacg caggagagcg cgccaatttc cagccacacg gcggtgacgc
      541 gcttaacatc gtgctgctcc gcctgccgtt ggataatttc aacggcgctc tggcaaagcg
      601 acaactcatg cattttcgcc actcctgcga ccaaacagca gggcgcgacg ccctgcgtgt
      661 ggtacatccg gattcgtgac tggcagcgaa aggatcattc gtgcgcagtc atccgtcagg
      721 cgttggccct cttcaatcga catactgtgc gaaagcggtg acatcagcga acaggagagg
      781 tattgcgaaa caccgtccag ttcgccaacg gtaaaggtca tggtgccata cggcagttgc
      841 agaccaattt tttcactcac tttgcgcagc ggccagagtt gatccgggcc ggggaagata
      901 actgcactca gcatccacgg ggtgatcaca caccccgtcc actgaccttc gaacagcgta
      961 aaatcagaaa catacaccgg cattgaagga tgcagaaaag agagatcgtg catcgaacgc
     1021 cgggcaattt cttcaaacgc tgcctgtact tgcgccttcg gggaggtctg gaaacctgct
     1081 atctcttcag tcatgaatcg cctcccgtgg gatggcttcc acgcctgatt cgcgcagcgc
     1141 agccagaacc tgctcaagcg caggttcaat cattgcttca accgtcggcg ttaagccgat
     1201 gtgtggctcc agcgattccg ggatcacgcc gaccagggtc agctttttcg gaaactcgcc
     1261 ggtgaagcgc agggccgaca agacgtcggc caggccaagc tgatgcggag agattttgtt
     1321 ggtaaacaac gccggaactt cttcatcccg caggatcatc atcgttcccg gcgcgctctt
     1381 cttcgacaca atggcatccg caataatcag atgatcgcga tttgccatgt cgccaagcag
     1441 ctccattccc gccgtgccgc catcgaggat ctcaacataa tccggcagaa tgtatcgttg
     1501 ctctaacgct tcaacaatcc gcacaccgat ggcttcatcg gtcagcaaaa tattgccgac
     1561 ccctaagact aaaatacgca ttacagaacc ttcactgaaa ccacttcgtt gccgtcagca
     1621 tccactacgt gtaccgcaca ggccatgcac gggtcgaagg agtgaatggt acgcaccact
     1681 tccagcggtt tattcggatc agcaaccggt gtacccacca gcgactgctc gtaaggaccg
     1741 acgtcatcat tgaagttacg cggaccagag ttccaggttg atggaacaac tgcctggtag
     1801 ttgctgatga taccgtcttt gatcaccatc cagtgagaga gcataccgcg cggcgcttcg
     1861 aggaagccaa cacctttgaa ctcacccgtt gccggaatgt tcggtttcac aaaggtggta
     1921 tgatcgcctt tgccgatatt ggtgatcagt gcactgtatt ggttttgcag gatatcctgc
     1981 aattcgcagc agtgaacggt acgaccaata atacggccca gcgtagagtg cagttgcgcc
     2041 acttccagcg tgttaccagt cagtttctga taaatcgcaa cgatttcatt cagtttgttc
     2101 tgggtagatt ctcgacctgc cgccagtttc accagcatat tagccagcgg acccacttct
     2161 accgttttgc cgtagaaagt cggtgatttc acccaggaat atttcccgtc gtcagaccaa
     2221 ccatcataag ccggaatggt ggtaccttcc cacggcgcct gtggcgcttc gtctttatac
     2281 caggagtgct tcgcgctttc ctgaatgcct ttgatcaggt attcatcgga atgagaagtg
     2341 atcggacgat acgaggacag atccgcattc tcaatgtagc cgcccgggaa caggaagctg
     2401 ccgtttttgc tgtcggtcgg gaattccggc acgctcaggt agttcaccgc acctttaccg
     2461 cgcgtcagcc attccgggta gaacgcggcg ataaccgcgg tatcaacctt ataaacctgc
     2521 tcaacaaagt cgctcagttt gtcgatgaaa gacttgatgt acatcaggcg ctcaaggttc
     2581 aacacgccca acccgtcgag gttgattggg ttcgcgacac cacccactgc caggttctga
     2641 atgtgcggcg ttttaccgcc cagcagcgcc acgacgcggt tagcgtcacg ctggcactcc
     2701 agcgcctgca ggtagtgcgc taccgcaatc aggttcactt ccggcggcag tttcatcgct
     2761 gggtgacccc agtagccatt agcgaaaata cccaactgac cgctggcaac cagatctttg
     2821 atcttgttct gaactttggt gaactcttcc gggctgttca gatgccaggt cgaaacgcct
     2881 ttcagcattt cggaggcttt ggttgggtca gcttgcagtg cagaagtgat atccacccag
     2941 tccagcgccg aaagctgata gaaatgaacg atatggtcat gcgtggtgtg cgcagccaga
     3001 atgatgttac ggatgtattg cgcgttaacc ggaacgtcga tattcagcgc actttctgcc
     3061 gcacgaacgg aagacagcgc gtgagtggta gtacatacgc cacagatacg ttgcacaatc
     3121 atccatgcat cgcgcggatc gcggtttttc acgatctctt ccatgccgcg ccacatggta
     3181 ccggaagccc atgctttcga aacgacgcca ttttcgattt cgcaatcgat gcgtaaatgc
     3241 ccctcaatac gggttaccgg atcaatagta attctctggc tcatgctttg ctcgcctcat
     3301 gacgattatg atcgttttgt tttaaaggag gaagtatcgg cagtagacga atgagtacga
     3361 tgtaagcgca aatctcaata gccacaaaac caatagaaat caacagttct tcccaggtcg
     3421 ggaagtaggc gtaaccgccg cccgggttga atgccaccag cgaataggtc agacgccagg
     3481 ttgcacaacc taacagtgcg ctcagtgctg acaggaacag catgcgggaa tcattacgca
     3541 gcttcgccac acgcagaacc accagcggga agagcatcag caggacttca atccagaaca
     3601 tcacggagta gaagtcaccg gcaaacgcta acgacagctt gtcgcgatag ataagctcgc
     3661 caaagcgcag cacgatgaaa atcgccagca acacactgat ggtgttggtc agcttgacga
     3721 acagactctt ttcatccgga ccgttgccac gcagacccgc ctgcaccagc gaaccttcaa
     3781 agatgacaat cgagaagccc atgatgaacg ccgtcagcag cgagaacagc ggcaacattt
     3841 catagctctg ccacaacgga tgcaccttgt agcccgccga gatcatcagt gaccccattg
     3901 aagactggtg catggtcggc aacagcgcgc caagtgcaat gatgaagaac atcaccttgt
     3961 tcagacgctt gagagaaacc ttccagccca gacgttcaaa cagtgccgga gcaaactcca
     4021 gtgccatcac gccgatatag atggtcatac agaccgccgt ctcgaacagt accgagttca
     4081 cgttgaagtg acccggaatg tagaagtacg gcaggttcca gtagcgaccc acgtcgatag
     4141 tgatcgacaa gccccccagt gagtaaccaa acagactcgc caacagcgcc ggacgcacca
     4201 gcggatggta ttgcccacgg ttaaagacgt ataccgccca cgccagcgcc cagccgccac
     4261 aggcaaagcc ggtaccaatc agcaggtcaa acgcgatcca cacgccccac gggaagccgc
     4321 cgttcaggtc agagacagag cccagaccga acaccagacg cttcacaatc aggagcatac
     4381 agatgacgat taacggtcca aaaatcatga ccggtttact gatgattttg ccgcccagcg
     4441 gttgtggatc atgactcatg atcgtctcct ccgtcgtgat ggtcgttttt ggtgttgcga
     4501 cgaaccagca cggttaagcc cgccagcaca gccagtggta gcatcatgcc tttatacagg
     4561 gtgtgttgaa tattttcgga acgcgcaccg gtagaaagat cgtccagttt cggcaggtcg
     4621 agattttcat aaggcacacc cgtcagtacc agaacctgag taccgccgcc ctctttctcg
     4681 ccgtacagat gcggataata tttcggcacc gtatgcaggt aagtgtcgcc agatttcagc
     4741 gtctgacgcg gatagtggta ttcgctgcca ggcttcagcg ccagacgttt tttcgcctcc
     4801 gccatcagct cttcacgcgt accaaaaatt accgcgcccg ccgggcacac ttctacgcag
     4861 ccaggcaaac cgcctttatc gagacgttcc acacctttct ggttgcacaa ctcgcactta
     4921 tgcagcgcac caaacgggtt gttgtagtcg tacttcggca cgttgtatgg gcaggcgacc
     4981 atgcagtaac ggcaaccggt gcacacatct ttgtcgtaat ggacaatgcc ggttttcgga
     5041 tcttttttca gcgcagagac cgggcacaca gagacacagt tcggatcgac gcagtgcata
     5101 cactgtttct taatgtacgc gtagccgttc tcctcctggt ctttgttgac ccctgtgccg
     5161 ctggtccaca cctgaatgat gttattggta tacggcgaca gtttgtcgtt gttcgaccag
     5221 gtctgttccc cttgcgggtt acgttcaggg aagttgatat cctgacactt ggtgacgcaa
     5281 gcctggcagc ctacgcacaa ggtcgagtcg tacaacatcc ccagcgatcc cggaattggc
     5341 gggcggtttt cagcagccgc atgactgaca gacggcagcg cgcccgtcag caatgccccg
     5401 caggaggctg ctttaataaa attacgtctg ttcacggtta ttctccccgt gagtcagcgt
     5461 tatctttctt ttgctgacga cccagttcac gcaccgccat cacgctgaca ccggcaacca
     5521 gcccaaccac accgccgagc aaaccaatag cgcctgcaga gacgttgccg ccctctttag
     5581 cgttaacatc cggtttctgt gaacgcggag tctgattttc gacgttggca agctgatgga
     5641 tgcctttatg gaagccgata ccttcttcgt tacagccata gcatgggtga ccaatcgcta
     5701 ccggccacac gccgccaaca tcgcagaatt gcagcgttga gcagttgccg taagtttctg
     5761 gccctttaca gccgaggtgg tacaggcacc agccttcacg gtggccttca tcaccgaact
     5821 ctttggcaaa acgaccagca tcgaagtgcg ggcgacgttc gcagtgttcg tgaatcagac
     5881 ggccataggc gaaggtcgga cgatttttgt catccagttt cggcggtttg ccgtaagtga
     5941 tgatgtgcgc aacggtcgcg aggaagttgt gcgggttcgg cgggcagccc ggaatattga
     6001 taacggtttt gcctggcaga acttcttgca ggctgactgc gccagttggg ttaactccag
     6061 ctgcggcaac accgccccac gcagagcagg aaccgatagc gataatcgct gctgcgcctt
     6121 ctgccgcttt gcggatgtga tccacaatcg gctcaccagc aaccatgcaa taaataccgt
     6181 tatcttttaa tgggatggaa ccatccacaa ccaacacata ctgccctttg tacttctcaa
     6241 gtgcgttatg tttgttctct tcgacctgat gaccgaaggc ggcggaaagc acttcgtgat
     6301 actccagaga gatagtctcc agcacgaggt tttctaccgt tggatgcgtt gcacgaagca
     6361 gagattccgt acaaccggtg cactcctgcg cgccaatcca gataactggc ggacgctgcg
     6421 ggttagtaac cgattcggcc atctctgcag cggctttgct acttaacccc atggtggcgg
     6481 ctaatgctgc acaaagcttc atgaaatcac gacggttaat gccgtgagaa tggatgaggg
     6541 tgttatctcc agtcatttat agttattccg ttgcgaagac ctggcatata ttttgcctca
     6601 atcgcaaaat caataatgcg atcgatgcgc catttaccac acatttatta tggttatcga
     6661 tatcatgata ctgcggcggg gcgctaaaac gaagggaaga agcattagtg taattaatta
     6721 aagcaagata atacgtatgt ttgatcaatt ttcgaggcga taaccggcca taaaaaagcg
     6781 caacgtagaa caggaattat tctcacgaaa gaaatccatt accatctctt tatccagtcc
     6841 atagcggcgc gtcagaatac ccgcttccca ggcgctaagc tggcgatctc cggtcttttc
     6901 gtacatccgg tgtgagtagc ctaatacaaa accgcgttta taatcggcac agaattttgt
     6961 cacattaacc gcactgtcgg catgcgttgc ttttaatccc gccattaagc ctttaccaaa
     7021 atggttattc atcgttcacc tcattcgcta tatatagcca tatatagcga tattttaggc
     7081 aaagaacgac ttttgcgcac gctatttttt catgcttgtt taagacgtaa tccagtaaga
     7141 gataaaccta tcaggagaga tatttatcga accatttcag tgtcctttgc caggcaagat
     7201 cggcggcaga tttgtcataa cggggcgtgg aatcattatg gaatccgtga ttaacccccg
     7261 gatagatata cgcctcataa accttattat tggctttcaa cgccgcctcg taagcaggcc
     7321 agccctcgtt gattcgggtg tccagttccg cgaagtggag tagtaaaggc gcttcaatct
     7381 tcgccacatc ggcagtgggt gcctgacgac cataaaacgg caccgcgcag gccagttccg
     7441 gatacgcgac agccgccgcg ttcgatacgc caccgccata gcaaaatccg gtaataccca
     7501 ctttgcctgc cgcttgcgga tagcgttgca taaactcaat tgcggcaaag aaatcattca
     7561 tcagtttggt tggatcaacc tgctgttgca gctcacgacc tttatcatca tttcccggat
     7621 aacctccaac ggaacttaag ccgtcaggtg ccagggcgat ataccccgcc ttcgccactc
     7681 gccgtgccac atcttcgata tacggattca gtccacgatt ctcatgcacc actaccacgg
     7741 ctggcgtttt gccgctcatt tttgcgggtt tcaccagata accccgtacc tcgccgtgac
     7801 catttggcga aggatacgtg atgtactcag caacaatctc cgggtcggta aactctacct
     7861 gagtcgccag cgcataattt ggcttgagca aatcaaacaa cgctaatgcc gtcatcccgc
     7921 ccaccgcata cttcgccgca aggttgagga actcacgttt cgagattttc ccgtgagcgt
     7981 aatagtcgta gtaatccaac aactcttgtg ggaaatcttt ggcggttaaa cgcggcatcg
     8041 ttgcactcct caactggtgt ttttttaagc aaagcataag cacgtgtttt tgcccagttt
     8101 ttcgtcactc tgtgagccag actacgggat acgcgctggc gaatcgctaa actagaaaca
     8161 ttgtttcgaa attgaacggt ggaaaggaga ggtcatggtc tggttagcga atcccgaacg
     8221 ttacgggcag atgcaatacc gctattgcgg aaaaagcggt ttacgcctgc ccgcgttatc
     8281 gctcggttta tggcacaatt tcggtcacgt taacgcgctg gaatcacagc gtgcgatcct
     8341 gcgtaaagcg tttgatttgg gcattacgca ctttgattta gccaacaatt acgggccgcc
     8401 tccaggaagc gcagaagaga actttggtcg cctgctgcgg gaggattttg ccgcttatcg
     8461 cgatgaactg attatctcta ccaaggctgg ctacgatatg tggcccggcc cttacggctc
     8521 tggcggttca cgtaaatacc tgctcgccag cctcgaccaa agcctgaagc gtatggggct
     8581 tgagtatgtc gatatctttt actctcatcg cgtcgatgaa aatacgccga tggaagaaac
     8641 cgcctctgcg ctggctcatg cggtacaaag cggtaaggcg ctgtatgtcg ggatctcctc
     8701 ttactcgcca gagcggacgc aaaaaatggt cgagttgctg cacgagtgga aaattccgct
     8761 tttaattcat caaccttcgt acaatttact gaaccgctgg gtggataaaa gcggcctgct
     8821 ggataccctg caaaataacg gcgtgggctg tattgccttt actcctctgg ctcagggatt
     8881 gctgaccgga aaatatctca acggcattcc gcaagattca cggatgtatc gtgaagggaa
     8941 taaagttcgt ggtctgacac cgaaaatgct taccgaagcc aacctcaaca gcctgcgctt
     9001 attgaatgaa atggcacagc agcgtggaca atcaatggcg caaatggcgt taagttggtt
     9061 gctgaaagat gagcgagtga cgtcggtatt gattggtgcc agccgcgcgg agcaacttga
     9121 ggagaacgtg caggcgctga ataatctgac atttagcacc gaggagctgg cgcagattga
     9181 tcagcatatc gccgatggcg agctgaatct gtggcaggcg tcgtccgata aatgacctgt
     9241 taataacggg cgcgcgaacc gcgcccgaat cagatcagtg attatgacga gtcagtcggt
     9301 caagatagcc catcacaaat gcagaaagca caaacgtcag atggataatg acgtaccaca
     9361 tcagtttgtt atccgggaca tttttcgcat ccataaagac gcgcagtagg tgaatggaag
     9421 aaattgccac aatcgacgct gctactttgt ttttcagcga cgttgcgtcc attttcccca
     9481 gccagttcag cttctctttg ttctcggaga tatccagctg tgagacgaaa ttctcataac
     9541 cggaaaacat caccatcacc agcaaaccgc caaccagcgt catatccacc agcgacagca
     9601 acacgaggat caaatctgat tccgccatcg agaagatatt cggcagtacg tgaataatct
     9661 cctggaagaa cttcagcgcc agggcaacta acgccagcga aaggccaaag tacacggggg
     9721 caagcagcca gcgagaagca tacattgcat tttcaagaaa acgttccata cattcctgtc
     9781 gtgtagttaa aacgggcaac agtatatcgc aattgagtaa acagcacgca acagcaaatc
     9841 aacatatacg ttaaaccttt gtcgcataat tctgaggttt agggatcttc ctggttccct
     9901 tatcaacgca tcgagagcgt ctacccttaa aggacgttga acctgaaggg agaaaaacga
     9961 tgtctcattt aaaagacccg accacgcagt attacactgg tgaatatccc aaacagaaac
    10021 aaccgacgcc aggcatccag gcgaagatga caccggtacc ggattgcggc gagaaaacct
    10081 atgttggtag cggtcgcctg aaagatcgta aagcactggt gacagggggc gattccggaa
    10141 taggtcgcgc tgccgccatc gcttacgcgc gtgaaggggc tgacgtggcg atcagttatc
    10201 ttcccgtgga agaagaagac gctcaggatg tgaaaaagat cattgaagaa tgcggacgca
    10261 aagccgttct gctgccaggc gatttaagcg atgagaaatt cgcccgttcg ctggttcacg
    10321 aagcgcataa ggcgttaggc gggctggata ttatggcgct ggtcgccggg aaacaggttg
    10381 ccattccgga tattgcagac ctcaccagcg aacagtttca aaagaccttt gccattaacg
    10441 ttttcgcgct gttctggcta acccaggaag cgatccccct gctaccgaaa ggtgcaagta
    10501 tcatcaccac ttcgtcaatc caggcatacc agccaagtcc gcatttactg gactatgcgg
    10561 ctacgaaggc ggcgattctg aactacagcc gtggcctggc aaaacaggtc gcggagaaag
    10621 gtattcgggt gaatattgtc gcgccaggcc cgatctggac agcactgcaa atttccggcg
    10681 gacaaacgca ggataagatc ccgcagtttg gtcagcaaac gccgatgaag cgtgcggggc
    10741 aaccggcgga actggcccct gtatatgttt atctggcaag tcaggagtcg agctacgtca
    10801 ccgcagaagt gcacggtgtg tgcggcggcg agcatttagg ttaaaaaaat gcccggttgt
    10861 gaaaagcaac cgggcatcat tgtgaattca ctcttacctg atgtggcgaa aacgccttat
    10921 ccgcctacaa acgcatgaag attcaacatg ttgcaataga ttttgtaggc ctgataagcg
    10981 tagcgcatca ggcattgagc acctaatgcc ggatgcgtcg tgaacgcctt atccggccta
    11041 caaacgcacg aagattcaac ctgttgcaat agattttgta ggcctgatga gcgtagcgca
    11101 tcaggcaatt ctactttact tcgctttggc ggtttcttcg ccgaccagac ctatcttcag
    11161 gtaacccgcc tgatgcagcg tatccattac cttcatcaac gtctcgtaat cgacggtttt
    11221 gtccgctcgg aagaagatgg tggtgtcttt cttgccttcg gttaacgcat tcaacgccgt
    11281 aatcattgtt tcatcggtga ccggatcgtt accgataaac atcgagttgt ctgccttcac
    11341 cgacagataa accggttttt ccgggcgcgg ctgcggcgtg ctggtagaag caggcaagtt
    11401 caccttcaca tctaccgtcg ctaacggtgc cgccaccata aagataatca gcagaaccaa
    11461 catcacgtcg ataaacggcg tcacgttgat atcatgcatt tcgccgttat cgtcgaggtt
    11521 ttcgttaaga tgcattgcca tcggatatta tcctgcgcgt aatttttgtg cgacacgaac
    11581 cggatgcgca gcggcgctgg cttccagatc caggtcacgg ctttgcagca acaatacctg
    11641 cgctgcaaca tcacccagca tcgctttaaa gccgccaatc tggcgtgcaa atacgttata
    11701 gataacgacc gcaggaatcg ctgccacgag gccgattgcc gttgctaaca gagcttctgc
    11761 gatacccggc gcaacgactg ccaggttagt ggtctgcgtt tgcgcgatac caataaagct
    11821 gttcatgatg ccccagaccg taccaaacag accaacgaac ggagaaatcg cgccgatggt
    11881 tgccagatag ccgttaccgc ggcccatttg acgacccact gcggcgaccc gacgctccag
    11941 acggaagctg gtacgttctt taataccttc gttatcgtcg ctgccttctg acagttccag
    12001 ctcattctgc gcttcattga gcaaatgcag gcttaagctt ttgctaccaa aatcagcggc
    12061 gatatcgttg gcctggttta aggaacgcgc ttcagccagc agttgctgct cgcgcttaag
    12121 gcgacgcttc tgattgaaga actctacgct cttactgaag aagattgccc aggtgactac
    12181 ggaggccaaa ataagcccaa tcatcacgca cttaacgaca atatcggcgt gctgatacat
    12241 accccagacg gaaaggtccg tctgcattaa attattaccc actgtgtatc tccaggacgc
    12301 aagtcacaaa atctgcgcat aataatatca aaacgacgtc gaattgatag tcgttctcat
    12361 tactatttgc atactgccgt acctttgctt tcttttcctt gcgtttacgc agtaaaaaag
    12421 tcaccagcac gccatttgcg aaaattttct gctttatgcc aattcttcag gatgcgcccg
    12481 cgaatattca tgctagttta gacatccaga cgtataaaaa caggaatccc gagatggcgg
    12541 acaaaaagct tgatactcaa ctggtgaatg caggacgcag caaaaaatac actctcggcg
    12601 cggtaaatag cgtgattcag cgcgcttctt cgctggtctt tgacagtgtg gaagccaaaa
    12661 agcacgcgac gcgcaatcac gccaatggcg agttgttcta tggacggcgc ggaacgttaa
    12721 cccatttctc cttacaacaa gcgatgtgtg aactggaagg tggcgcaggc tgcgtgctat
    12781 ttccctgcgg ggcggcagcg gttgctaatt ccattcttgc ttttgtcgaa cagggcgatc
    12841 atgtgttgat gaccaacacc gcctatgaac cgagtcagga tttctgtagc aaaatcctca
    12901 gcaaactggg cgtaacgaca tcgtggtttg atccgctgat tggtgccgat atcgttaagc
    12961 atctgcagcc aaacactaaa atcgtgtttc tggaatcgcc aggctccatc accatggaag
    13021 tccacgacgt tccggcgatt gttgccgccg tgcgcagtgt ggtcccggat gccatcatta
    13081 tgatcgacaa cacctgggca gccggtgtgc tgtttaaggc gctggatttt ggcatcgatg
    13141 tttccattca ggccgctacc aaatatctgg ttgggcattc agatgcgatg attggcactg
    13201 ccgtgtgcaa tgcccgttgc tgggagcagc tgcgggagaa tgcctatctg atgggccaga
    13261 tggtcgatgc cgataccgcc tatataacca gccgtggcct gcgcacatta ggtgtgcgtt
    13321 tgcgtcaaca tcatgaaagc agtctgaaag tggctgaatg gctggcagaa catccgcaag
    13381 ttgcgcgagt taaccaccct gctctgcctg gcagtaaagg ccacgaattc tggaaacgag
    13441 actttacagg cagcagcggg ctattttcct ttgtgcttaa gaaaaaactc agtaatgaag
    13501 agctggcgaa ctatctggat aacttcagtt tattcagcat ggcctactcg tggggcgggt
    13561 atgaatcgtt gatcctggcg aatcaaccag aacatatcgc cgccattcgc ccacaaggcg
    13621 agatcgattt tagcgggacc ttgattcgcc tgcatattgg tctggaagat gtcgacgatc
    13681 tgattgccga tctggacgcc ggttttgcgc gaattgtata acattgccac ttttggacaa
    13741 ttttgcagac atttaattgt gaaaagtctt aaattgttgc gtccgggatc aaggcgtccc
    13801 ggacgaatca ggagtacaat aggcagataa aggcttaaac gctgttccac aggaaagtcc
    13861 atggctgtta ttcaagatat catcgctgcg ctctggcaac acgactttgc cgcgctggcg
    13921 gatcctcata ttgttagcgt tgtttacttt gtcatgtttg ccacgctgtt tttagaaaac
    13981 ggcctgctgc ccgcctcatt tttgccaggc gacagcttgt tgatactggc aggcgcattg
    14041 attgcccaag gggttatgga ttttctgcct acgattgcga ttctgaccgc cgcagcaagt
    14101 ctgggctgct ggctaagtta tattcagggg cgctggttag ggaataccaa aacggtgaaa
    14161 ggctggctgg cacagcttcc tgctaaatat caccagcgcg ccacctgcat gtttgaccgc
    14221 cacggtctgc tggcgctgct ggctggacgt tttcttgcat ttgtccgtac gctgctgcca
    14281 accatggcgg gaatttccgg tctgccaaac cgccgcttcc agtttttcaa ctggttaagt
    14341 ggattgctgt gggtcagcgt ggtaaccagt tttggctatg ccttaagtat gattccgttc
    14401 gttaaacgcc atgaagatca ggtaatgacg ttcctgatga tcctgccaat tgccttgtta
    14461 accgctggct tgttaggcac gctgtttgtg gtgattaaaa aaaaatactg taacgcctga
    14521 cgattttccc cgttcccggc tgctgtaccg ggaacgtatt taattcccct gcatcgcccg
    14581 cattcttgcc gcatcttccc ccggcgtcac accgaagtaa cgtttaaact cacggctaaa
    14641 ttgcgatgcg ctttcatagc cgacgcgcat cgctgctgcg ctagccttca tgccgtcatg
    14701 gatgatcatc atccgcgcct tatgcagacg gtaattcttc aaatactgca acggcgaggt
    14761 gctggtgaca gacttaaaat tatggtggaa cgccgatacg ctcatgttgg cttctgccgc
    14821 cagttgctcg acgctcaggt tttcggtgta tttattctca atccgtttca gcacgcggct
    14881 aatcagactg aagtgagtct ggcgactgac cagcgccagt aacgcgccgc cgcaaggtcc
    14941 ggtcagcacg tagtacagaa tttcgcggat gatctgtttg ccgagaatac gcgcatccag
    15001 tggtcgctcc atcacgtcga gtaaccgctc cgccgcgcat aaaatctctt ctgataacgt
    15061 ggcggagtta atcccgctgg ctgccatcga cggctggaaa tgctcatctt cgccaatgtc
    15121 catcaacagt tcctgtaact gcaaaatatc gacattgaga cgcaaccctg ccagcggcac
    15181 ctctgacgtg gcataggttt cgcactcaaa cggcaacggc accgtcagca gcaggtattc
    15241 attggcatca taacgaaaca cgcgttcatt gatataaccg attttatgcc cggaaaagag
    15301 aattatgatg ccaggctcgt acatcaccgg tgtacgtgcg aaaggcgtct cgccatacaa
    15361 caaacgcaca tcgggcaaca gttctgacaa actattttct ttatttttca gtttattaac
    15421 tttatccgcc agcaagcggc aaatctcttc acgtttcata tcgcgtaatt tcttaggaat
    15481 aatgcggcaa tttgattgtg cgcaattttg tagcatttct ccagcactct ggagaaatag
    15541 gcaagacatt ggcagaaatg agcattgaga gccagggcgc tggcgatcac aatgaaaaac
    15601 atcaggcaga tcgttctctg ccctcatatt ggcccagcaa agggagcaag taatgaacaa
    15661 ctttaatctg cacaccccaa cccgcattct gtttggtaaa ggcgcaatcg ctggtttacg
    15721 cgaacaaatt cctcacgatg ctcgcgtatt gattacctac ggtggcggca gcgtgaaaaa
    15781 aaccggcgtt ctcgatcaag ttctggatgc cctgaaaggc atggacgtgc tggaatttgg
    15841 cggtattgag ccaaacccgg cttatgaaac gctgatgaac gccgtgaaac tggttcgcga
    15901 acagaaagtg actttcctgc tggcggttgg cggcggttct gtactggacg gcaccaaatt
    15961 tatcgccgca gcggctaact atccggaaaa tatcgatccg tggcacattc tgcaaacggg
    16021 cggtaaagag attaaaagcg ccatcccgat gggctgtgtg ctgacgctgc cagcaaccgg
    16081 ttcagaatcc aacgcaggcg cggtgatctc ccgtaaaacc acaggcgaca agcaggcgtt
    16141 ccattctgcc catgttcagc cggtatttgc cgtgctcgat ccggtttata cctacaccct
    16201 gccgccgcgt caggtggcta acggcgtagt ggacgccttt gtacacaccg tggaacagta
    16261 tgttaccaaa ccggttgatg ccaaaattca ggaccgtttc gcagaaggca ttttgctgac
    16321 gctaatcgaa gatggtccga aagccctgaa agagccagaa aactacgatg tgcgcgccaa
    16381 cgtcatgtgg gcggcgactc aggcgctgaa cggtttgatt ggcgctggcg taccgcagga
    16441 ctgggcaacg catatgctgg gccacgaact gactgcgatg cacggtctgg atcacgcgca
    16501 aacactggct atcgtcctgc ctgcactgtg gaatgaaaaa cgcgagacca agcgcgctaa
    16561 gctgctgcaa tatgctgaac gcgtctggaa catcactgaa ggttccgatg atgagcgtat
    16621 tgacgccgcg attgccgaaa cccgcaattt ctttgagcaa ttaggcgtgc cgacccacct
    16681 ctccgactac ggtctggacg gcagctccat cccggctttg ctgaaaaaac tggaagagca
    16741 cggcatgacc caactgggcg aaaatcatga cattacgctg gatgtcagcc gccgtatata
    16801 cgaagccgcc cgctaagctt tttacgcctc aaactttcgt tttcgggcat ttcgtccaga
    16861 cttaagttca caacacctca ccggagcctg ctccggtgag ttcatataaa ggaggaacgt
    16921 atggctaatc caaccgttat taagctacag gatggcaatg tcatgcccca gttgggactg
    16981 ggcgtctggc aagcaagtaa tgaggaagta atcaccgcca ttcaaaaagc gttagaagtg
    17041 ggttatcgct cgattgatac cgccgcggcc tataagaacg aagaaggtgt cggcaaagcc
    17101 ctgaaaaatg cctcagtcaa cagagaagaa ctgttcatca ccactaagct gtggaacgac
    17161 gaccacaagc gcccccgcga agccctgctc gacagcctga aaaaactaca gcttgattat
    17221 atcgacctct acttaatgca ctggcccgtt cccgctatcg accattatgt cgaagcatgg
    17281 aaaggcatga tcgaattgca aaaagaggga ttaatcaaaa gcatcggcgt gtgcaacttc
    17341 cagatccatc acctgcaacg cctgattgat gaaactggcg tgacgcctgt gataaaccag
    17401 atcgaacttc acccgctgat gcaacaacgc cagctacatg cctggaacgc gacacacaaa
    17461 atccagaccg aatcctggag cccattagcg caaggaggga aaggcgtttt cgatcagaaa
    17521 gtcattcgcg atctggcaga taaatacggc aaaactccgg cgcagattgt tatccgctgg
    17581 catctggata gcggcctggt ggtgatcccg aaatcggtca caccttcacg cattgtcgaa
    17641 aactttgatg tctgggattt ccgtctcgac aaagacgaac tcggcgaaat tgcaaaactc
    17701 gatcagggca agcgtctcgg tcccgatcct gaccagttcg gcggctaaca tgcaaattct
    17761 cccggtggcg gtaatgttcc gctaccggac ttttcagaaa tcatttattc ccctcgcgtc
    17821 ccgcccgttg ttactcttcc ttgttcagga atgccaaata taaggacatc atcatgcaga
    17881 gccggaagct cttaaaagaa caactcatct atatccggga taaacgcaac ggagaggtga
    17941 aaaacagatg aaaataatac ttctgttttt agcagccctg gcaagtttta ccgtacacgc
    18001 acagcccccc tcactgaccg tagaacaaac agtccggcat atttatcaga actataaatc
    18061 agatgccact gccccttatt ttggtgaaat cggagagcgg gcgataactt ctgcgcgtat
    18121 tcaacaggcg cttaccctga acgacaatct tacgctgccg ggcaatattg gctggctgga
    18181 ttatgatccg gtttgtgatt gtcaggattt tggcgatctg gtgctagaaa gcgttgcgat
    18241 aacccaaact gacgccgatc atgccgatgc cgttgtgcgc tttcgtatct ttaaagatga
    18301 taaagaaaag accacgcaga cactgaaaat ggtggcggaa aatggtcgtt gggtcattga
    18361 cgatattgtc agcaatcatg gcagcgtctt acaagcagtt aatagcgaga atgaaaaaac
    18421 gctggccgct ttagcttcgt tgcaaaaaga acagccggaa gcctttgttg ccgaactctt
    18481 tgaacatatt gctgattata gctggccgtg gacgtgggtg gtttccgact cttaccgcca
    18541 ggcggttaat gccttctata aaaccacctt caagacggcc aataatcccg atgaagatat
    18601 gcaaatagaa cggcaattta tttacgacaa tccgatctgt tttggcgaag agtcgctatt
    18661 ttcacgcgtt gatgaaattc gagtcctgga gaaaaccgcc gattccgccc gtattcatgt
    18721 tcgttttacg ctgaccaatg gcaacaacga agagcaagaa ctggttttac agcggcgcga
    18781 aggcaagtgg gaaatcgctg attttatccg cccgaacagc ggcagcctac ttaagcagat
    18841 tgaggcaaaa accgccgcca gattaaagca atgagctgaa ttaaataaca attagccgga
    18901 acaataaata aaagggaaca ctatatgaaa acgattttca ccgtgggagc tgttgttctg
    18961 gcaacctgct tgctcagtgg ctgcgtcaat gagcaaaagg tcaatcagct ggcgagcaat
    19021 gtgcaaacat taaatgccaa aatcgcccgg cttgagcagg atatgaaagc actacgccca
    19081 caaatctatg ctgccaaatc cgaagctaac agagccaata cgcgtcttga tgctcaggac
    19141 tattttgatt gcctgcgctg cttgcgtatg tacgcagaat gataaaaaaa tccccggcag
    19201 catgtcagtt gccggggatt ttttttaacg tccaaccgcc gctttagggc gtttcttcgc
    19261 accagcattc accggacgag attgcgtaga cgacgctttt tttgccgtag caggcgtctg
    19321 acgctgggtc gccatcggcg tatgtttcgt caacgccgga cgggtattgc ggttctggcg
    19381 acgagcttca cgcatctctt caatggttgg cgcaggcact aagcaatcgc gacggctgcc
    19441 aatcagatgc tttttgccca tcgcttccag cgcctggcgg attaacggcc agtttgccgg
    19501 atcgtggtaa cgcaacaacg ctttatgcaa acgacgctgt ttgtcgccct tcggtacgaa
    19561 gacgtcttcg ctcttataac caatcttcgc cagcgggttt ttcccggtgt aatacatggt
    19621 ggttgagttc gccagcggcg atgggtagaa gttctgtacc tggtcgagac ggaaacgatg
    19681 ctttttcagc cacagcgcca gattcaccat atcttcatca cgcgtaccgg ggtgcgcgga
    19741 gatgaaatag gggatcagat actgctcttt acctgcctgt tttgagtaag tatcgaacag
    19801 ctctttaaag cggtcatagc tgcccatgcc cggcttcatc atcttcgata acggcccttc
    19861 ttcggtatgt tccggggcaa tcttcagata accgccgacg tgatgggtcg ccaactcttt
    19921 gatatagcgc ggatcttcca cggcgatgtc ataacgtacg cctgaggcga tgaggatttt
    19981 tttaatgcct ttcagatcac gcgcacggcg atagaggttg atcgtcggtt cgtggttagt
    20041 gtccatgtgc ggacaaatat ccggataaac gcacgacaaa cggcgacaag tttgttcagc
    20101 gcgtggcgat ttgcagcgca acatatacat gttggcagtt ggcccaccga gatcggaaat
    20161 cacgcccgta aaacctggaa cggtgtcgcg gatcgcttcg atctcattaa tgatcgaatc
    20221 ttccgaacgg ctctgaataa tgcgcccttc gtgctcggta atagaacaga aagaacagcc
    20281 gccaaagcag ccgcgcataa tgttgaccga aaaacggatc atttcgtaag ccggaatacg
    20341 ggcattgcca taggccggat gtggcacgcg cttgtacggc agcgcaaaaa cgctgtccat
    20401 ctcttcggta gaaagcggga tagcaggcgg gttgatccac acatagcggt caccgtgttt
    20461 ttgcatcaat gcgcgggcgc agcctgggtt ggtttcgtgg tgcagaatgc gcgaagcatg
    20521 ggcgtacagc actttatcgc ccttcacttt ctcgaaagaa ggcagcaaca cgtaggtttt
    20581 ttcccacggt ttcgggcgcg gtggctgcac ggttacggct ttggcttcct gctttttcgg
    20641 tgccaccggt ttgttatccg cgcacggcaa atcttcacca tacggatgcg ggattgggtc
    20701 gatttttcca ggggtatcaa gacgggtgga atccacgccg ctccagccag gcagcgcctc
    20761 tttcacgata atcgcggtat tacgcacatc gcggatttca ctaatcggct cgcccatcgc
    20821 cagacggtgc gccacctcca ccagcggacg ctcaccgtta ccaaacatca gcatgtcggc
    20881 tttcgaatcc accagcacgg aacggcgcac ggtatcggac cagtaatcat aatgtgcggt
    20941 acggcgcaga ctagcctcaa taccgccgag gatcaccggt acatctttcc acgcctcttt
    21001 acaacgctgg gtataaacca gtgtggcgcg atccgggcgc ttacccgcga cgttatccgg
    21061 cgtgtaggca tcgtcatgac gtaaacggcg atcggcggta taacggttga tcatcgaatc
    21121 catgttgcca gcagtaacac cgaaaaacag attcggttta cccagacgca tgaaatcgtc
    21181 tttgctgctc cagtctggct gggcgatgat cccgacgcga aagccctgtg cttccagcat
    21241 acgaccgcaa atcgccatcc cgaagcttgg gtgatcgaca tacgcgtcgc cagtaaccaa
    21301 aatgatgtcg cagctatccc agccaagttg atccatctct tcacgagaca tcggcaaaaa
    21361 cggtgccggt ccaaaacagg cggcccagta ctgcggccag gagaacaggt cgcgatccgg
    21421 ttggatcagg gagatagagc tcattttgct tccagaaatg ataaaaaaat aatcaaaggc
    21481 cggggattat aagccggaac gaaagagaaa tcgaaaggta ttccatactc gccctcctcg
    21541 ggcgagtatg aagattacgg taccggattg accaaaagtt gccctatcga gccacggtcc
    21601 gccatttcca gcgtctgact gttgaagtag aacgggaagt gcgcccagga aggctgaccg
    21661 aaataaacaa gcagctccac ttgtccgtca acccaaacgg tatctttcca gcctctgtct
    21721 tccgggaacg gcatcgcgcc attcacgtta cggatctgga acattacgcc ttcaatatgg
    21781 aacgcttgcg gctcgtccgc gcgtaccgtc cagcgttccc acgttccttg ctgcgcggtg
    21841 acatcaatac ggttgacgtc ccacagctgt ccattaatac ccgggtcatc acccagactg
    21901 atatcgcgac tgcgaattgg cgaaccagcc atgatttcag ttggcagcaa gcgcatcgga
    21961 agactgtctg tgaccagcgg cagaaggccg gttgggcgca gcgttagcac cagggtagaa
    22021 accagaatac tggatggctc aaagaagccg cgaatacgat caacaatgct cgccgcttcg
    22081 ccacaggtga tcgacacttc atcgccgttg ctcatatcca ccagaatctc gcggcgctcg
    22141 cccggtgcca gcgaaagttg cttcaccgat acaggagcag gcaggaatcc ctgatcgcca
    22201 gaaatcacat gtaacgggcg accatcgctc atctgtagtt gatagcgacg agagttcgac
    22261 gcgttcagca gtcgcaagcg cacccagcca cgcgagactt caacgtacgg gctttgtaca
    22321 ccgttaacca gcagcgtatc accaacaaag ccgccgcttc ccggttcgtt gtattctggc
    22381 gtaccaaagt tatccagccg tttatcctgg ataatgaccg gaaaatcatc cacaccataa
    22441 tggttgggga taggcagcga cttgctgact tcatcttcca ccagccacat tccggcaagg
    22501 ccgttataga cctgctgagc cgtgcggttg ggagtattgg cgtgatacca cagagtagct
    22561 gcgttctggc gaataggcag tacgggtgcc cagtcagcgt ttggcgacat catccgtgcc
    22621 ggaccgccca tcagcgggcc tggtacctgt agcccggcca ccgtcattga gacattttct
    22681 gtcaggcggt tgctgtaaat aagcttaaca tcgtcgccct tccagacgcg gatagtcggc
    22741 cccaggtaac gaccattgat tccccagacc gacgcgcgtg tccctggcgt aaatgaccaa
    22801 tgcgcacgtt gtacagtcat aaacagcggt tgcccacggc gagattcaag tagcggcgga
    22861 acgggtagcg gttgctgttg cccggctgcg ctggccttca ggggaacagc gcctgcacaa
    22921 agtgcaatcc ccgatgcctg aatgaactga cgccgactga gtgacatatt tgctccatgt
    22981 aaaactggct aaagtaatac cgtgcaggaa agtgttcccc gcaaaaatac agattgccga
    23041 cttaaacttt tccggcggct tcgcgttctg cgacttcttt atcgagctcg gcgatttttt
    23101 gttccattat cgaacgacaa tgggcagcca gctcacgaac ctgatctttg ccatactgac
    23161 tgacgtcaat tggcggcagc atttcgacaa tcaccagacc gttgtgcagt cgattaagat
    23221 taatcttatt cgaagttgta gagacgcaca cgggaataat cgggacgccc gccgcaattg
    23281 ccgcgtgaaa tgctccagtc ttgaacggta gcaggccgcg accacggctg cgggttcctt
    23341 ccgggaacat ccagatggaa atacggcgtt ttttgaaatg attcacgact tccgcaatgg
    23401 tgccgtgagc tttagtgcga ttgtttctgt cgatcaataa gttgccggtt aaccagtaca
    23461 actgcccgaa gaaggggatc cacagcaagc tctttttacc taccgtcacc gtcggcggtt
    23521 gcacaatgtt cgatgctgtc accatgtcat agttgttctg gtggttagcg atatagatag
    23581 cattgccgta gctttcagca tctgcaggtt tgcggcactc aactttcagg ccgaacagcg
    23641 gcgcaagacg gccaaacata tgcccaaagg tggccacatg tttcgggtta cgcgggctga
    23701 aaaggcagta aatggagccg aatacacaga ctaagatgct gtaaatcacg gtaataataa
    23761 gacgaaagat atatagcata acaccctctg aaggtctgag agactggcat tgtacgtcac
    23821 ctgaaatcag gttagggcat tgttaaaagc cgctctctgg aaaagcgtat tgttaatcgc
    23881 aacgcatgaa taaacaacgg tttcaaggga atttttatcg tttccggggg ttgaatacgc
    23941 tgccggatga cgacttaacg tttcatccgg cgttccttgc aagcgggagg aaacaggccc
    24001 tccccggcat attactcttc gctatcaccg ctgctggcac ggcgaggaga gtcgatctca
    24061 acacgatcga tacgctgcaa accgcgcatc aacgtaccgc ggcgtccacg ttcgccagtg
    24121 actttctgta actcttccgg gcgcagttta attttgcgtt tcccaacatg aatggtcagc
    24181 gtgctttgcg gcggcagaac gtacaattgc gccagaccat cttctccacg cgcggcttct
    24241 gccgatggaa tgttgataat cttgttgcct ttgcccttcg acagctgcgg cagatcgctt
    24301 accgggaaca tcaacatacg gcctgcctga gtgattgcca gcagcatatc ggaagcatct
    24361 tcaatcacca ccggcggcat aacatgggca ttttccggta aggtgatcaa agccttacct
    24421 gcacggttac gcgccaccag atcgttaaag gtgcagacga aaccgtaacc cgcatcggaa
    24481 gccatcagca gtttctgatc gtcgctttcc atcagcatat ggtcaacggt cgccccaggc
    24541 ggcaacgtta atttgccggt gagtggttcg ccctgaccac gcgccgacgg cagcgtaatc
    24601 gggtcgatgg catagctacg accggtggaa tcaacaaaca ctaccggttg gttgctctta
    24661 cctttcaccg ccgctttgaa gctatcaccc gctttataat tcaggcccgg cgcgtcgata
    24721 tcatggcctt tagcgctgcg tacccagccc atctgcgaca gcacaatggt gacaggttca
    24781 gacggcagca tgtcgtgctc gctcatcgct ttcgcttctt cgcgttcctg caacggcgaa
    24841 cgacgatcgt caccgtaggc ttgcgcgtct gcctgcagtt ctttcttcag caggttattc
    24901 attttacgct cggaagccaa aatgccctgc aactggtcgc gctctttttc cagttcactc
    24961 tgctcaccgc gaatcttcat ctcttccagt ttggcaagat gacgcagttt cagttcgagg
    25021 atcgcttccg cctgggtttc cgtaaggcca aaccgcgaca tcagcgccgg tttcggttca
    25081 tcttcgttac gaatgatctc aatcacttcg tcgatgttga gaaacgccac cagcaaacct
    25141 tccaggatat gcaggcgctt gaggactttc tccagacgat agttcagtcg gcggcgcacg
    25201 gtatcgcgac ggaacaccag ccattcggag aggatttcca gcaggttttt caccgccgga
    25261 cgaccatcca gaccgatcat attgaggtta atgcgatagc tcttttccag atcggtggta
    25321 gcgaagaggt ggttcatcac ctgatccata tccacgcggt tggaacgcgg cacaatcacc
    25381 agacgggtcg ggttctcgtg gtcagattca tcgcgcagat cgtcaaccat cggcagcttt
    25441 ttgttgcgca tttgcgcagc aatttgctcc agtacgcgcg cacctgaaac ctgatgcggt
    25501 aatgcgctga taaccaccgc gccatcttct ttcttccaca ccgcgcgcat acgcactgaa
    25561 ccacgtccgt tctcgtagat tttacggatc tcggcgcgcg aagtgataat ttccgcttca
    25621 gtcggataat ccggcccctg cacgatatcc agcagctgat cgagcgtggt tttcggctgg
    25681 tcgattaatg cgattgccgc ctgagctact tcacgcaggt tatgcggtgg aatatcggtc
    25741 gccatgccga cggcaatacc ggtggtgccg ttaagcaaaa tgtttggcag acgagcaggc
    25801 agcattttcg gctcctgcaa agtgccgtcg aagtttggca cccagtcagc cgtcccctgc
    25861 cccagctcgc tcaatagcag ctcggaatat ttcgacaacc gggattcggt gtaacgcatt
    25921 gccgcgaacg atttcggatc gtccggcgcg ccccagttcc cctgaccatc aaccagcgga
    25981 taacggtaag agaacggctg cgccatcagg accatcgctt cataacaggc gctatcgccg
    26041 tgcggatggt atttacccag tacgtcaccg acggtacggg ccgatttttt aaatttggcg
    26101 ctggcattca ggcccagttc agacatcgca tacacaatgc ggcgctgaac aggtttaaga
    26161 ccatcgccaa taaacggcaa cgcacggtcc atgatcacgt acatggagta gtttaagtag
    26221 gcgttttccg taaattcatg tagcgcaagg cgctctgcca tatcgctcat taattctgat
    26281 tcctcaactt attcgccagc cttcaaaggg gcaatattgc cggagatact acattatctg
    26341 ccgcgtcgag tcacaggaga tcagcgtgaa tagcgccgcc ggacgtgctc cgacggcgat
    26401 aaaggcatca atgtgccttg atatacaact ctttgctgta gacttgatcg gcatagaggg
    26461 cagcacaagg ttgcgcccat gccacaccac tcggcatggg ggtccgctcc gggcgattcg
    26521 agaagttgag gttatgcgag tccagggaag cctaaagcat caaagtagtc gactgtaagt
    26581 atacggttca gcccagttta gctgtgtctc caccagtgcc ccgcgcctcc tgccataagt
    26641 gcggcttgct catggatacc cccgagacgg cttacggcgc accggataat aaatttcgcg
    26701 tatacatggt attccttacc ggagaaatta taagcccaac aacaatacgc ctgtggcatt
    26761 gttcgctcaa acttatcgcg agtgatttgg ctcacactcc ggtaaagatt ccccatcacg
    26821 ccaacggcac ataaacatcc gtttccagtc gctgctctgt caccccttcg gcaagattgg
    26881 tgtagtgaaa cagaatcggt gctttacgca ttttctcgcc gcttgcaggc agccagtggc
    26941 gaataatgcc ccatatcgtg tgtgaaatat cgtccagctc gccaacgtgg cgggccacgg
    27001 cataacgtcc accggtaagt tcaccattgc tcacaccata acgattatcg ggaatcggtt
    27061 cgctaacgct gccgcagata tcaaagcgaa acgcttccgg tgcggtggtg gcagggtcgt
    27121 cccaggcgac gccaaaagtc tggctttggt taacaggaga aagccccgtc tctttacgcc
    27181 acatgataaa tttcgccaca ctgtagttga gcaactcagg gctacagcgg tgcggcaaca
    27241 tcgccacagg gattgatggg aaatcgataa tgtttacatc cagtgtcagg tttgtcattt
    27301 tgcctccctg cgaaattatt cccgggaacg cgtcccggga gcggtaacaa ttacggattt
    27361 actttgcgga tctgtttgac gtcaatttca acagaattcc agtctttatc gacttcaccc
    27421 tgaatctcaa ccgtatcttt cggcgtcacc gtcacaccgt tccagcgttt gtggtcgata
    27481 tcaacattga tagtaccgct ggcatcttta aacacgtaga gatcgtcaga gatgcgttca
    27541 acgatattgc cgcgcagggt tacccaggtg tcgtcacgca gggattttgc gctttctacg
    27601 gtcgttacgc tgccgttcgg cccctggaat cctccggcct gactttgcgt tgccgatggg
    27661 ccagaaaaac cgccctgctc tgctgccatc accggtgcgc tgcacagggc cattactgcg
    27721 attactgctg cgaatttttt catgtttatt actcccttta atgtctgttt ccgagcattt
    27781 aacaagatag tccttaacaa cttcttaagg gaaaaaaata aaatttagtg ctgtacagag
    27841 cgcgttacaa cacggtttac tggcagcaaa tacggttatc gcagggatga aaaaatgcga
    27901 attttactga tagaagatga catgctgatt ggcgacggca tcaaaacggg ccttagtaaa
    27961 atgggtttta gcgtcgactg gtttacacaa ggtcgtcagg gaaaagaggc gctttatagc
    28021 gcgccttatg atgcggtgat cctggattta accttaccag gcatggatgg tcgcgatatt
    28081 ttgcgcgaat ggcgagaaaa aggtcagcgt gagccggtac tgatcctgac cgcgcgcgat
    28141 gcgctggagg aacgtgtaga agggctgcgt ctgggagctg acgattatct gtgtaaacct
    28201 tttgcgttga tagaagtcgc cgccaggctg gaagctctga tgcgccgaac caacggccag
    28261 gccagcaacg agctgcgcca cggtaacgtc atgctcgacc ccggcaaacg tatcgccacg
    28321 ctggctggcg aacccttaac actgaaacca aaagaatttg ccctgctgga attactgatg
    28381 cgtaacgctg gtcgggtact gccgcgcaaa ctgattgaag agaaactgta tacctgggac
    28441 gaagaggtca ccagtaatgc cgttgaagtg catgtgcatc atctgcgacg caaactcggt
    28501 agtgatttta ttcgtaccgt gcatggtatt ggctacacat taggtgagaa atgaaattta
    28561 cccaacgtct tagtctgcgc gtcaggctga cgctaatctt tttaattctg gcctcggtga
    28621 cctggctgct ttccagcttt gtcgcctgga aacaaacaac ggataacgtc gatgaattgt
    28681 tcgacaccca actgatgctg tttgccaagc ggttaagtac gctcgatctc aacgaaatca
    28741 acgcggcgga tcgcatggca cagacgccaa ataaattaaa acacggtcat gttgatgacg
    28801 atgcgctgac ctttgccatc tttacccacg acggcagaat ggtccttaac gatggcgata
    28861 acggagaaga tattccttat agctatcaac gggaaggttt tgctgacggg caactggtgg
    28921 gcgataaaga tcaatggcgt tttgtctgga tgacctcacc tgatggcaaa tatcgcatcg
    28981 ttgttggtca ggaatgggaa taccgtgaag acatggcgct ggcgattgtt gccgggcaat
    29041 tgatcccgtg gctggtcgca ctgccgatta tgttaatcat catgatggta ctattgggtc
    29101 gtgaactcgc gccgctgaac aaactggcgc tggcgctgcg tatgcgtgac cctgactcgg
    29161 aaaaaccact aaacgcgact ggcgtaccca gcgaagtgcg tccgttggtt gagtcgctaa
    29221 atcaactgtt cgcccgcaca catgcgatga tggttcgtga acgacgcttt acctccgacg
    29281 cagctcacga actacgtagc ccgttaacgg cgctgaaagt gcaaaccgaa gttgcgcagc
    29341 tttctgacga tgatccgcaa gcgcggaaaa aagcgctgct tcaattacat tacgggatcg
    29401 atcgcgctac tcgtctggtt gatcaactgc tcactctatc gcggctggac tcactggata
    29461 accttcagga cgtcgcggag atcccgcttg aagatctcct ccaatcgtcg gtgatggata
    29521 tttaccacac ggcgcagcag gcgaaaattg acgtgcgact gacactcaat gcccacggca
    29581 tcaaacgcac cggacaaccg ctattgctaa gtttgttggt gcgaaatttg ctggataacg
    29641 ccgtgcgcta cagtccacag ggcagcgtga tagacgtcac gctgaatgct gataatttca
    29701 tcgtgaggga taacggcccc ggtgtgacgc cagaggctct ggcgcgaatt ggcgaacgct
    29761 tctatcgccc ccccggacaa accgctaccg gcagtggact tgggctatcg attgtccagc
    29821 gaatcgccaa attgcatggc atgaatgttg agtttgggaa tgcggaacaa ggtggatttg
    29881 aggcgaaggt aagctggtaa cttctctgtc tatgagagcc gttaaaacga ctctcataga
    29941 ttttactaat agcaaaatat aaaccgtccc caaaaaagcc accaaccaca aaccagacaa
    30001 ataccgagcg agaatacata tacccaaaac tcgaacattt cccgcataaa gagttttctt
    30061 aagataagaa taataagtgg cgtaagaaga aaaaatgctg caatcattgc ttgcaatata
    30121 cgatcttcgc ctgaaacgga aggtatactg caaatattgt ctcccgactc aagcatccag
    30181 tcatacttat tgaaagcaaa aaaagcatct attaaccaat aagtaagcat tatgtataac
    30241 agagcttcaa atattgtttg aattttatgc tttaacatat atcagtacgc tcataaaaat
    30301 ccat
//
LOCUS       DAZUDJ010000061        30041 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.061, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000061 DAZUDJ010000000
VERSION     DAZUDJ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30041
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.061"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..487)
                     /locus_tag="ACHY1N_003571"
     CDS             complement(<1..487)
                     /locus_tag="ACHY1N_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4045801.1"
                     /translation="MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRI
                     LGKEKTLALGVYPEVSLSEARTKRDEARKLISEGVDPCEQKRAKKVVPDLQLSFEHIA
                     RRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEAKQIYEI
                     AS"
     gene            complement(685..760)
                     /locus_tag="ACHY1N_003572"
     tRNA            complement(685..760)
                     /locus_tag="ACHY1N_003572"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(725..727),aa:Phe,seq:gaa)
     gene            complement(867..1442)
                     /locus_tag="ACHY1N_003573"
     CDS             complement(867..1442)
                     /locus_tag="ACHY1N_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4045802.1"
                     /translation="MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPD
                     KEAILYDALRYLSQQIDVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIA
                     ACTFYPDPGHPIHQLADQQKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRML
                     VNRSQADVDTAHRLAEDILRFARCRQGGALT"
     gene            complement(1479..3176)
                     /gene="dsbD"
                     /locus_tag="ACHY1N_003574"
     CDS             complement(1479..3176)
                     /gene="dsbD"
                     /locus_tag="ACHY1N_003574"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HFS4045803.1"
                     /translation="MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFTFDFQQN
                     QHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTL
                     PVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAASQPVSVSQQEQHT
                     AQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMA
                     LTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLT
                     LMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYAL
                     GMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDVWGLRLWSA
                     LGVAFFGWAFITSLQAKRGWMRVVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNF
                     TQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQA
                     NVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP"
     gene            complement(3152..3490)
                     /gene="cutA"
                     /locus_tag="ACHY1N_003575"
     CDS             complement(3152..3490)
                     /gene="cutA"
                     /locus_tag="ACHY1N_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HFS4045804.1"
                     /translation="MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIP
                     GATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTD
                     YLSWLNASLR"
     gene            complement(3606..4907)
                     /gene="dcuA"
                     /locus_tag="ACHY1N_003576"
     CDS             complement(3606..4907)
                     /gene="dcuA"
                     /locus_tag="ACHY1N_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuA"
                     /protein_id="HFS4045805.1"
                     /translation="MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGN
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE
                     IKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVI
                     CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML"
     gene            complement(5025..6461)
                     /gene="aspA"
                     /locus_tag="ACHY1N_003577"
     CDS             complement(5025..6461)
                     /gene="aspA"
                     /locus_tag="ACHY1N_003577"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313147.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008797 - aspartate ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HFS4045806.1"
                     /translation="MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSL
                     IKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNI
                     QRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGA
                     YVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCIN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMHPAYKAKRYTDESEQ"
     gene            6798..7274
                     /locus_tag="ACHY1N_003578"
     CDS             6798..7274
                     /locus_tag="ACHY1N_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418564.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FxsA family protein"
                     /protein_id="HFS4045807.1"
                     /translation="MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGM
                     SLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD"
     gene            complement(7290..8546)
                     /gene="yjeH"
                     /locus_tag="ACHY1N_003579"
     CDS             complement(7290..8546)
                     /gene="yjeH"
                     /locus_tag="ACHY1N_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine/branched-chain amino acid
                     transporter"
                     /protein_id="HFS4045808.1"
                     /translation="MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWA
                     WPVLIILVFPIAIVFAILGRHYPSAGGVAHFVGMAFGSRLERVTGWLFLSVIPVGLPA
                     ALQIAAGFGQAMFGWHSWQLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIV
                     AIWWAGDIKPANIPFPAPGNIELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFP
                     RALMIGLLLAGLVYWGCTVVVLHFDAYGEKMAAAASLPKIVVQLFGVGALWIACVIGY
                     LACFASLNIYIQSFARLVWSQAQHNPDHYLARLSSRHIPNNALNAVLGCCVVSTLVIH
                     ALEINLDALIIYANGIFIMIYLLCMLAGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKS
                     LYALIMLAGLWLLLPKRKTPENGITT"
     gene            8822..9115
                     /locus_tag="ACHY1N_003580"
     CDS             8822..9115
                     /locus_tag="ACHY1N_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFS4045809.1"
                     /translation="MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVG
                     NGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            9159..10805
                     /gene="groL"
                     /locus_tag="ACHY1N_003581"
     CDS             9159..10805
                     /gene="groL"
                     /locus_tag="ACHY1N_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFS4045810.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITE
                     GLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM"
     gene            10943..11296
                     /locus_tag="ACHY1N_003582"
     CDS             10943..11296
                     /locus_tag="ACHY1N_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HFS4045811.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELSAAGQSVRIVDEQPGAECQ
                     LIGTATGKQSNWLSGQHGEEGGSMRGAANDLRNQAAAMGGNVIYGISSPSQGMLSSFV
                     PTDSQIIGQVYKCPN"
     gene            complement(11499..12368)
                     /locus_tag="ACHY1N_003583"
     CDS             complement(11499..12368)
                     /locus_tag="ACHY1N_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HFS4045812.1"
                     /translation="MAISIKGVNTGVIRKSNNFIALALKIKEPRNKESLFFMSVMELR
                     DLLIALESRMHQKHKLDAAARLQYEQARDKVIKKMAENIPEILVDELKNADINRRVNT
                     LELTDNQGENLTFVLTLHDGSKCELVVNELQIEMLARAIIHAINNAEMRELALRITSL
                     LDFLPLYDVDCQENGNLEYDTYSQPEWKHNLFDHYLAVLYRFKDESGKEQFSGAVVKT
                     REATPGKEIEAITRRMLDFSPRLKKLAGVPCQVYVRTVAANNAQPLTQDQCLRALHHL
                     RVQSTSKTAPQAK"
     gene            complement(12758..13786)
                     /gene="epmB"
                     /locus_tag="ACHY1N_003584"
     CDS             complement(12758..13786)
                     /gene="epmB"
                     /locus_tag="ACHY1N_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0072581 - protein-N6-(L-lysyl)-L-lysine
                     modification to protein-N6-(beta-lysyl)-L-lysine [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HFS4045813.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPDDPLLRQVLTSQDEFVVASGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTVLEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITEALVERFARSTL
                     QILLVNHINHANEVDETFRQAMAKLRRVGVTLLNQSVLLRGVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
     gene            13828..14394
                     /gene="efp"
                     /locus_tag="ACHY1N_003585"
     CDS             13828..14394
                     /gene="efp"
                     /locus_tag="ACHY1N_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFS4045814.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            14446..14571
                     /gene="ecnA"
                     /locus_tag="ACHY1N_003586"
     CDS             14446..14571
                     /gene="ecnA"
                     /locus_tag="ACHY1N_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HFS4045815.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            14682..14828
                     /gene="ecnB"
                     /locus_tag="ACHY1N_003587"
     CDS             14682..14828
                     /gene="ecnB"
                     /locus_tag="ACHY1N_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HFS4045816.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            15010..15327
                     /gene="sugE"
                     /locus_tag="ACHY1N_003588"
     CDS             15010..15327
                     /gene="sugE"
                     /locus_tag="ACHY1N_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HFS4045817.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(15324..15857)
                     /gene="blc"
                     /locus_tag="ACHY1N_003589"
     CDS             complement(15324..15857)
                     /gene="blc"
                     /locus_tag="ACHY1N_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HFS4045818.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDRGMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(15946..17079)
                     /locus_tag="ACHY1N_003590"
     CDS             complement(15946..17079)
                     /locus_tag="ACHY1N_003590"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HFS4045819.1"
                     /translation="MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAETYGVKSTIEDMACWVRSNMNPRDINDKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSGNKIALAAHPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ"
     gene            complement(17142..17501)
                     /gene="frdD"
                     /locus_tag="ACHY1N_003591"
     CDS             complement(17142..17501)
                     /gene="frdD"
                     /locus_tag="ACHY1N_003591"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HFS4045820.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGIVTI"
     gene            complement(17512..17907)
                     /gene="frdC"
                     /locus_tag="ACHY1N_003592"
     CDS             complement(17512..17907)
                     /gene="frdC"
                     /locus_tag="ACHY1N_003592"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HFS4045821.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            complement(17918..18652)
                     /gene="frdB"
                     /locus_tag="ACHY1N_003593"
     CDS             complement(17918..18652)
                     /gene="frdB"
                     /locus_tag="ACHY1N_003593"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HFS4045822.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            complement(18645..20453)
                     /gene="frdA"
                     /locus_tag="ACHY1N_003594"
     CDS             complement(18645..20453)
                     /gene="frdA"
                     /locus_tag="ACHY1N_003594"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HFS4045823.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGVVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            20778..21755
                     /gene="epmA"
                     /locus_tag="ACHY1N_003595"
     CDS             20778..21755
                     /gene="epmA"
                     /locus_tag="ACHY1N_003595"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HFS4045824.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            21974..23476
                     /gene="yjeM"
                     /locus_tag="ACHY1N_003596"
     CDS             21974..23476
                     /gene="yjeM"
                     /locus_tag="ACHY1N_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HFS4045825.1"
                     /translation="MPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARIT
                     AVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGS
                     VNLGNITYVLMKSLGVTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYS
                     PLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTASAFFNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTRMSAMIATVVVVLVVTFANV
                     FTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRMANKPELALD"
     gene            complement(23627..26950)
                     /gene="mscM"
                     /locus_tag="ACHY1N_003597"
     CDS             complement(23627..26950)
                     /gene="mscM"
                     /locus_tag="ACHY1N_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HFS4045826.1"
                     /translation="MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPE
                     VVEALQSALNALEERKGSLERIKQYQQVIDNYPKLSATLRAQLNNMRDEPRSVSPGMS
                     TDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
                     TLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQL
                     DAYLQALRNQLNSQRQLEAERALESTELLAENSADLPKDIVAQFKINRELSAALNQQA
                     QRMDLVASQQRQATSQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILEAQLRTQRELLNS
                     LLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDL
                     RRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVG
                     KVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLL
                     WVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDRE
                     FSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVA
                     ILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVIDNPAPEVFL
                     VDLQQGIQIFELRIYAAEMGHRMPIRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNG
                     KQTGRTLTSAGKGRQAGSL"
     gene            complement(26972..27940)
                     /gene="asd"
                     /locus_tag="ACHY1N_003598"
     CDS             complement(26972..27940)
                     /gene="asd"
                     /locus_tag="ACHY1N_003598"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313166.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004609 - phosphatidylserine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="archaetidylserine decarboxylase"
                     /protein_id="HFS4045827.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEN
                     KILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSV
                     TKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV"
     gene            complement(28037..29089)
                     /gene="rsgA"
                     /locus_tag="ACHY1N_003599"
     CDS             complement(28037..29089)
                     /gene="rsgA"
                     /locus_tag="ACHY1N_003599"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313167.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HFS4045828.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIV
                     ISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
                     KIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            29184..29729
                     /gene="orn"
                     /locus_tag="ACHY1N_003600"
     CDS             29184..29729
                     /gene="orn"
                     /locus_tag="ACHY1N_003600"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HFS4045829.1"
                     /translation="MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGP
                     TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
     gene            29940..30015
                     /locus_tag="ACHY1N_003601"
     tRNA            29940..30015
                     /locus_tag="ACHY1N_003601"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29973..29975,aa:Gly,seq:gcc)
BASE COUNT         7213 a         7596 c         7854 g         7378 t
ORIGIN      
        1 gactggcgat ttcataaatt tgtttagctt ctgcagcacg aacagggata agcaggtccg
       61 gggtattgag tgttgtgata tcccgattgc cgataaaggg gaatacgtgt gtctcgaggc
      121 ttttgagtac tttatcgctg tgtgattgtg cccattgttt attactggca tgccagcgtc
      181 gtgcaatatg ttcgaaagag agttgtaaat cagggactac ttttttagct cttttctgtt
      241 cgcaagggtc aaccccctcc gaaatcagtt ttcgggcctc atcccgtttt gtacgagctt
      301 cggagagaga tacttctgga tacacaccaa gtgccagagt cttctcttta cccagaatac
      361 gataacggag acgccagtaa cgggaaccat taggatgtac cagcaggaac atgccagccc
      421 cgtcagtgag tttataagcc ttgtcagtgg gctttgcagc ccggattttt gcgtcagtca
      481 gtgccatagt tcagccttct gaatgcgtta aagagggtac aaattctgtc gaactggggt
      541 atgcccgcaa ttatacccac acaatgaggt tgatgtgggg agaatttggt tgagttcggt
      601 agaattgatt tggaggaaga acacttaaat catggtgttc tgaaacgaaa aacggacctc
      661 cgtggaggtc cgttgatatg aatttggtgc ccggactcgg aatcgaacca aggacacggg
      721 gattttcaat cccctgctct accgactgag ctatccgggc aacggggcgc attaaaccgt
      781 aatctgcaca tctcgtcaac ctaatttcag taaaagcgat tcaactgctt aagattgcgg
      841 caaatcgctt cttttctgtg tttctgtcag gtcaatgcac caccctggcg gcagcgggcg
      901 aagcgcagga tatcttccgc cagccgatgt gcagtgtcga catccgcctg gctacgattc
      961 accagcattc ggcttaaaca gccttccagc accagttcca tctgctttgc taccatcgcc
     1021 ggatcgtcaa cttccagcgt ggttaacagt tcgtgggtga aatcgtaggc cgcgcttttt
     1081 tgctgatcgg ccagttgatg aatagggtgg ccaggatcgg gataaaacgt acaggcagcg
     1141 ataaatagac agcccggata gcggttgttt ttaacgcact ccgataacgc ctgataacgt
     1201 gccagcaact tttgttcggc ggtttgcgtt tcgtccagca tcagctgacg acgccagaca
     1261 tctatctgtt ggctaagata acgcagcgca tcgtagagga ttgcctcttt gtctggccag
     1321 aagcggcgta gctcgtccag tggataatcc acacgttcag caaccatctc cagcgtggtg
     1381 ttggcaatcc cttgtaattc taataatttc agggcttctc ccagtacatc ttcacgttgc
     1441 acgctatttt cctccgtctt tcccactgca agtgtcgttc acggttggcg atcgcgcaaa
     1501 tgtgcgctga aggtttcagc atccataaag cccgtgacgc gtgcttgtgg atgctcctgg
     1561 ccttgtccgt caaaaaagag aattgtcggt aggccaagga cattaagatg ctttaacagc
     1621 gccacatctt gtgcgtcgtt ggccgtgacg ttggcctgaa gtaagaccgt gtctgctaac
     1681 gctttttgca cctgcgggtc gctgaaggtg tatttctcaa actctttaca ggcgacgcac
     1741 cagtcggcat aaagatctaa catcaccggt ttgcctttgg cttcaacgag cgcctgattt
     1801 aactcatcta ccgttttgat ttgtgtaaag ttgagatgcg tctgagtttg cgcggtatgc
     1861 gtcgcaccaa atgcccaatc ctgaagtggg cgcacgctaa ccaatgccgc tgccagcagg
     1921 attatttgca ccacgcgcat ccagccgcgt ttagcctgta ggctggtgat aaaggcccag
     1981 ccaaagaatg cgacacccag cgccgaccac aagcgtaatc cccatacatc accaatcact
     2041 cgctccagca ggaagaccgg cagtgcgagg atcacaaaac caaacgcggt tttgacttgt
     2101 tccatccacg ggccgctttt cggcagcaag cggttaccaa agacggtaat tagcatcagc
     2161 ggcaggccca tgcccaacgc atagagataa agcgtgccgc cgcccagcca catgttcccg
     2221 ctttgggcga tatacagcag aatcgcgcta agcggtgcgg tggtgcatgg tgaacagatc
     2281 agtccggcaa tcgcccccat aacaaacaca ccgccaggtg agccgccctg ttggcgattg
     2341 ctcatcaacg tgagacgtgt ttgcagcgaa gaggggagtt gtagagtaaa caagccaaac
     2401 attgacatcg ccagcaaggt aaagacgatg gcgaggccaa tgagcacgta tgggtgctgt
     2461 agcgccgcct ggaactgtaa ccctgcggcg gcaactacca gacccagcgc cgtgtaagtc
     2521 agtgccatcc cctgcacata aataaaggtc agcaacaatg ctctggcagt ggagagccgc
     2581 tgtttaccac ccagcacgat gccagaaatc agtgggtaca ttggcagcac gcatggcgta
     2641 aaggcgatac caataccgat caacaacgcc cagagcgcgg aaaagggcaa ttgcgcggtg
     2701 tgctgctctt gctgcgaaac agacacaggc tgtgacgctg cgttgttggc gaccacttcg
     2761 cttaacggaa cggttttggt ttctggcgga taacagaaac cggcatcagc acagccctgg
     2821 taggtgacag ttaacgtcgc tcccgcactc gcctggttga tggttacggg aagcgtcagc
     2881 cgatcgcggt aaatctcgct tttgccgtaa aactcatctt catgccagac gccttgtggc
     2941 agctgcacgt cggcaatttt cgcgtgttcc ggcgtaatgc ggatctgttt acggtagagg
     3001 tagtaaccgt ctttgatctg ccaggtcaga ttaaggtcat gttggttttg ctgaaaatca
     3061 aaagtaaagg cttgatccgc ggggacaaat tgtgaacgtc ccggcgcgtc gaataatccg
     3121 gcaaaaacgg aagtgctgca aagtagcagg atcagcgtaa agatgcgttg agccatgaga
     3181 ggtaatctgt gtctccgtgt gtaacaggta aaaccagaag ttccggggtt tgatatggat
     3241 gatgagactt caggcattcc agcagtgcct gctggtgaga tacggtagtt tttaaaatca
     3301 tctgcacttc gtattcttgc tccagcttac cttcccagta atagagagag gtagcgccgg
     3361 ggatcaaggt cgcgcaggcc gccagttttt ccgccagcac tttggcggct aaatcctggg
     3421 ctgtcgcttc atccggtgcg gtacatagca ccacgacaga cgcggtattc gaactttttt
     3481 catcaagcat aaacacctcg caagaacaga tggaaccgca agagagaggt cactatacaa
     3541 cggacggggg aaggatgtta gtcggcggga aagaaagcgg ggcgtgaacg ccccgcgatt
     3601 ggtcattaca gcatgaagct acccagcacg aagccgaagc aaacggccag ggcaacaccc
     3661 agagtacccg ggatgaagaa cggatggttg aagacgaatt taccgatacg ggttgtaccc
     3721 gtgtcatcca tctgtaccgc agcaaccagc gtcgggtagg tcggcagaat gaacagacca
     3781 gacaccgcag cgaaagaagc aacagcggtc agcggtgaaa cgttcagtgc cagggccatc
     3841 ggcatcagtg cttttgcggt tgcagcctga gagtacagca gagcagaagc aaagaagaag
     3901 atgacggcca gcagccacgg atgaccctga atcacttcac cagcggtatc tttgatccag
     3961 tcgatgttgt tggaaacgaa agtatcgccc agccacgcaa cacccaggat acaaatacag
     4021 gcgctcatac ctgctttgaa ggtgctggag ttgaggatgt tgtcggtatc gactttacag
     4081 ataacggtgg tcagagttgc aacgctgagc atgatgatca ggattgcgtt ggtggtgttc
     4141 atcagcggtt tttcaaccag acccatgctt gggctgttga tgattgcata gataaccacg
     4201 ccaactacgc ccagcaggaa cagccagacg gacgtttttg caccggattt gatttcaatc
     4261 tgcttttcac cgcgcagttc aaccaggccc tcttccagac gcttgcgata aatcggatcg
     4321 tcagagagtt tggagttgaa tagcatagtg accagaaagg acatcaccag aaccgccagc
     4381 agggtggacg ggatgaccac ggagagcaga tggaggtagc tgatgccatg accttccatc
     4441 acggaagaca tgtaaaccac tgccgctgag attggcgatg cggtgatcgc aatctgcgcg
     4501 gataccactg cagtagacag cggacggcaa ggtttgacgc cttgttcctt cgcaacttca
     4561 gcgataactg gcagtgtcgc cagagatatg ttgccagtac cagcaaagat agtcaggaaa
     4621 taggtcacga tcggtgcgag gatcgtgatg tatttcgggt tacggcgcag cagcttttct
     4681 gtctgatgaa ccagatagtc cagaccgcca gcaacctgca tggcagaaat agcggcgata
     4741 accgccatga taatggaaat gacatcgaac gggatgttac cgggtttaac gccaatagcg
     4801 gcaagaacca gcacccccaa tccgcctgca aaaccaatac ctattccccc caatctggcg
     4861 cccaagaaga tcgccagcaa aactatgatg agttctacaa ctagcatatt agccttcctt
     4921 gttttttaac aagttgatat taggttgtta tttttaagtt actgctcaca agaaaaaagg
     4981 cacgtcatct gacgtgcctt ctttatttgt actaccctgt acgattactg ttcgctttca
     5041 tcagtatagc gttttgcttt gtaagccggg tgcatcagat tctgtacgga gaaaatatcg
     5101 tcaagttccg cttcagtcaa cagaccgcgt tccagaacga cttcacgtac actcttaccg
     5161 gtttcggcac agattttacc cacgatgtca ccgttgtggt gaccgatgaa cgggttcagg
     5221 taagtaacga taccgataga gttgtaaacg taaccttcgc acacttcttt gttagcagtg
     5281 atgccgttaa tgcatttttc cagcaggttg tagcaagcgt tggtcagaat gtgaacggat
     5341 tcgaacatgg cctggccaat gaccggctcc ataacgttca actgcagctg acctgcttct
     5401 gctgccatgg taacagtggt gtcgttaccg atgactttga agcatacctg gttaaccact
     5461 tccggaacaa ccgggtttac tttagctggc atgatggaag agcccgcctg cagttccggc
     5521 aggttgatct cgttcaggcc ggcacgtgga ccagaagaga gcaagcgcag gtcgttacag
     5581 attttggaca tcttcacagc caggcgtttc agcgcgccgt gaaccataac ataagcgccg
     5641 cagtcagagg tcgcttcgat caggtcttca gccggtacgc atgggaagcc agtgacttca
     5701 gccagttttt tcactgccag cggagagtac tctttcggcg tgttcagacc agtaccgatt
     5761 gctgttgcgc caaggttaac ttccagcagc agttcagcgg tacgttggat atttttcact
     5821 tcttctttca gcaggatgct gaaagcgcgg aattcctgac cgagggtcat cggtactgcg
     5881 tcctgcagct gggtacgacc cattttcagg atgtcctgga attcgacagc tttacgttca
     5941 aagccttcac gcagttggtt aatcgcatct accagcttaa tcagggaaga gtaaactgcg
     6001 atacggaaac cggtcgggta ggcgtcgtta gtggactgac atttgttaac atggtcgttc
     6061 gggttcaggt actgatattc acctttctgg tgacccatca gttccagacc gatattggcc
     6121 agcacttcgt tggtgttcat gtttacggaa gtacctgcgc cgccctggta gacgtctacc
     6181 gggaactgat ccatgcattt tccgttgttc aggacttcat cacatgcggc aatgatggca
     6241 ttcgctacac ttttaggaat ggtttgcagc tctttgtttg ccatagctgc ggctttttta
     6301 accattacca taccgcgaac aaattcagga atatcactga ttttgttgtt gctgatatag
     6361 aagttttcaa tcgctctcag agtgtgaaca ccatagtagg catcagctgg aacttccctg
     6421 gtacccaaca gatcttcttc gatacgaatg ttgtttgaca tgtgaacctt ctttttcaag
     6481 ctgccaatga tttgctttaa acacacagaa tatatgtggt ttcgaatgtt tttcgaccga
     6541 cgattatccc ctgcatcgac cgaatacccg agatcatatg ctgcttgagg atttctaccg
     6601 taatctggat cactttaagt gtcggttttt accccttaat tattaatttg tgaaatagat
     6661 caccgctttg ggattactac caaaaatagt tgcgcaaaca tcttgaaatt ttgctaatga
     6721 ccacaatata agctgaacgc gattcgcaac ccattcaggt agccgggttt taccggctgc
     6781 tattacagga gaaacctttg cgctggttac cttttattgc cattttcctt tatgtctata
     6841 ttgagatttc aatctttatt caggttgccc atgtattggg ggtattgctg accctcgtgc
     6901 tggttatatt cacgtcagtt atcgggatgt cactggtacg taaccagggc tttaagaatt
     6961 tcgtgctgat gcagcaaaaa atggcggcgg gtgaaaaccc agcggcggag atgattaaaa
     7021 gtgtttcgct gatcattgcc ggtttgctgc ttttattacc gggctttttc accgacttcc
     7081 tcggtcttct gcttttatta ccgccggtgc aaaagcatct gacagtgaag ttgatgccgc
     7141 atttgcgctt ttctcgtatg ccaggcggcg gttttagcgc cgggaccggt ggcggtaata
     7201 cttttgatgg tgagtaccag cgaaaggatg atgagcgcga ccgccttgat cataaagacg
     7261 atcgccagga ttaatgtcga aacgccggat tatgtggtta tgccattttc cggcgttttt
     7321 cgttttggca gcaacagcca taaccccgcc agcatgatca gcgcatagag acttttccag
     7381 ccgaccattg ccagtaacag aacgcataac agcccgccaa ccaccgccag tagtcgataa
     7441 cgtccttgca ataatttaca gcctgccagc atgcataaca gataaatcat aataaagatg
     7501 ccattggcat aaataataag agcgtccaga ttgatctcta aagcatgaat caccaacgtg
     7561 ctcaccacac agcagccgag caccgcattg agggcattat tcgggatatg gcgagaagag
     7621 aggcgtgcca ggtagtggtc aggattatgt tgcgcctgcg accagaccag gcgggcgaag
     7681 ctctgtatat aaatgttgag actggcaaag caggccagat agccaatcac gcaggcaatc
     7741 cataacgctc ctacaccgaa caactgcact acaatttttg gaagcgatgc tgccgccgcc
     7801 attttttcac cataggcgtc gaagtgtaag acgactaccg tacagcccca gtagactaat
     7861 cctgccagca gcagaccaat catcaatgcg cgaggaaaat cacgctctgg atttttaaat
     7921 tccgaggcaa gatgggcaaa tgcttccaga ccgacaaaac accagaacat cactgataac
     7981 gcagcaaata acccggtaag ttcgatatta ccaggtgccg ggaaggggat attcgcaggt
     8041 ttgatatcgc ccgcccacca gatagcgaca atcagcgcga cgataagtcc ggcaataacg
     8101 gtttgtagat tagcactgga actggcaccg cgagtaccga tataccacac cagcgccagc
     8161 gtaccgagtt ctgccaacaa cagttgccag ctatgccagc caaacattgc ctggccgaac
     8221 ccggcggcaa tttgtagcgc ggcaggcaaa cccacgggaa tgaccgataa aaacaaccag
     8281 ccggtgactc gctcaagtcg cgaaccaaac gccataccga cgaagtgcgc gacaccgcct
     8341 gcgctgggat agtggcgacc cagaatcgca aacacaatcg caatcgggaa cactaagata
     8401 atcaaaacgg gccacgccca caggctgtta ttgcccgcta ccagcgcagc taacgcagga
     8461 acggcaaaca cgccagtgcc taataatgac gtcgatagca ggccaatgcc ttgggccagc
     8521 cccagttctt gtttgagtcc actcatgggt tgatatccga ttgcgcccaa attttgggca
     8581 actgcgtaga ttttcgatgg tagcacaatc agattcgctt atgacggcga tgaagaaatt
     8641 gcgatgaaat gtgaggtgaa tcagggtttt cacccgattt tgtgctgatc agaatttttt
     8701 ttctttttcc cccttgaagg ggcgaagcct catccccatt tctctggtca ccagccggga
     8761 aaccacgtaa gctccggcgt cacccataac agatacggac tttctcaaag gagagttatc
     8821 aatgaatatt cgtccattgc atgatcgcgt gatcgtcaag cgtaaagaag ttgaaactaa
     8881 atctgctggc ggcatcgttc tgaccggctc tgcagcggct aaatccaccc gcggcgaagt
     8941 gctggctgtc ggcaatggcc gtatccttga aaatggcgaa gtgaagccgc tggatgtgaa
     9001 agttggcgac atcgttattt tcaacgatgg ctacggtgtg aaatctgaga agatcgacaa
     9061 tgaagaagtg ttgatcatgt ccgaaagcga cattctggca attgttgaag cgtaatcctc
     9121 gcacgacact gaacatacga atttaaggaa taaagataat ggcagctaaa gacgtaaaat
     9181 tcggtaacga cgctcgtgtg aaaatgctgc gcggcgtaaa cgtactggca gatgcagtga
     9241 aagttaccct cggtccgaaa ggccgtaacg tagttctgga taaatctttc ggtgcaccga
     9301 ccatcaccaa agatggtgtt tccgttgctc gtgaaatcga actggaagac aagttcgaaa
     9361 atatgggtgc gcagatggtg aaagaagttg cctctaaagc gaacgacgct gcaggcgacg
     9421 gtaccaccac tgcaactgta ctggctcagg ctatcatcac tgagggtctg aaagctgttg
     9481 ctgcgggcat gaacccgatg gacctgaaac gtggtatcga caaagccgtt accgctgcag
     9541 ttgaagaact gaaagcgctg tccgtaccgt gctctgactc taaagcgatt gctcaggttg
     9601 gtaccatctc cgctaactcc gacgaaaccg taggtaaact gatcgctgaa gcgatggaca
     9661 aagtcggtaa agaaggcgtt atcaccgttg aagacggtac cggtctgcag gacgaactgg
     9721 acgtggttga aggtatgcag ttcgaccgtg gctacctgtc tccttacttc atcaacaagc
     9781 cggaaactgg cgcagtagaa ctggaaagcc cgttcatcct gctggctgac aagaaaatct
     9841 ctaacatccg cgaaatgctg ccggttctgg aagctgttgc caaagcaggc aaaccgctgc
     9901 tgatcatcgc tgaagatgtt gaaggcgaag cgctggcaac tctggttgtt aacaccatgc
     9961 gtggcatcgt gaaagttgct gcggttaaag ctccgggctt cggcgatcgt cgtaaagcta
    10021 tgctgcagga tatcgcaacc ctgactggcg gtaccgtaat ctctgaagag atcggtatgg
    10081 agctggaaaa agcaaccctg gaagacctgg gtcaggctaa acgtgttgtg atcaacaaag
    10141 acaccaccac tatcatcgat ggcgtgggtg aagaagctgc aatccagggc cgtgttgctc
    10201 agatccgtca gcagattgaa gaagcaactt ctgactacga ccgtgaaaaa ctgcaggaac
    10261 gcgtagcgaa actggcaggc ggcgttgcag ttatcaaagt aggtgctgct accgaagttg
    10321 aaatgaaaga gaaaaaagca cgcgttgaag acgccctgca cgcgacccgt gctgcggtag
    10381 aagaaggcgt ggttgctggt ggtggtgttg cgctgatccg cgtagcgtct aaactggctg
    10441 acctgcgtgg tcagaacgaa gaccagaacg tgggtatcaa agttgcactg cgtgcaatgg
    10501 aagctccgct gcgtcagatc gtcctgaact gcggcgaaga accgtctgtt gttgctaaca
    10561 ccgttaaagg cggcgacggc aactacggtt acaacgcagc aaccgaagaa tacggcaaca
    10621 tgatcgacat gggtatcctg gacccaacca aagtaacccg ttctgctctg cagtacgcgg
    10681 cttctgtggc tggcctgatg atcaccaccg agtgcatggt taccgacctg ccgaaaaatg
    10741 atgcagctga cttaggcgct gctggcggta tgggcggcat gggtggcatg ggcggcatga
    10801 tgtaattgcc ctgcacctcg cagaaataaa caaacccccg ggcagaaatg tctgggggtt
    10861 tttcttttgg tcatctttct agtataagat tcagacacgg acgacgcgag tggcgtccag
    10921 ctcattgatt atggggaata acatgcacgt aaaatactta gcagggattg tcggtgccgc
    10981 gctactgatg gcgggttgta gctccagcaa cgaattgagt gctgccggtc agagtgtacg
    11041 cattgtggac gagcagccag gcgcagagtg ccagctgatt ggtactgcga caggtaagca
    11101 aagcaactgg ctttccgggc aacacggaga agagggcggt tctatgcgcg gcgcagcaaa
    11161 cgatctgcgc aaccaggcgg ctgcaatggg cggtaacgtg atttatggca tcagcagccc
    11221 gtcgcaggga atgttgtcca gttttgtccc gacggatagc cagattatcg gtcaggttta
    11281 taagtgcccg aactgatgtg atccagaggc tgggtgacaa acgtatcatt gcctgatgcg
    11341 cttcgcttat caggcctaca gcaggcattg caactgattg aatgcttgag aatttgtagg
    11401 ccggataagg cgtttacgcc gcatccggca tgaccaacga tcacgttatc agtcatttca
    11461 ggctggatgg ctccagcctc gcattagcaa agatgagatt atttcgcctg tggtgcagtt
    11521 ttgctggtgg attgaacacg taagtgatgc agcgcgcgta agcattgatc ctgggttagc
    11581 ggttgggcgt tattcgccgc tacggtgcga acatagacct gacatggcac acccgcgagt
    11641 tttttcagtc gtgggctgaa atcaagcatt cggcgagtga tcgcctctat ttctttaccc
    11701 ggcgttgctt cacgcgtttt caccactgcg ccgctaaatt gttctttgcc actttcatct
    11761 ttaaagcggt aaagcaccgc cagataatgg tcgaacaggt tatgtttcca ttccggttgg
    11821 gaataggtgt catattccag attgccattt tcctggcagt caacgtcata taacggcagg
    11881 aaatctaaca gtgaggtaat acgtaatgcc agttcacgca tttccgcatt attaattgca
    11941 tgaatgattg ctcgcgccag catttcaatc tgcaactcat tgacgactaa ctcacatttg
    12001 ctaccgtcat gtagcgttaa tacgaaggta agattttcgc cttgattatc ggtaagttcc
    12061 agcgtgttaa cccgacgatt aatatcggca tttttaagct catcaaccag aatttctggg
    12121 atgttttctg ccattttttt aatgacttta tcgcgagctt gctcatactg aaggcgtgca
    12181 gcagcatcca gtttatgctt ttgatgcata cgactttcca gcgcaatcag caggtcgcgc
    12241 agttccatga cagacataaa gaacaacgat tctttattgc gaggttcttt aattttcagc
    12301 gccagtgcaa tgaaattatt actcttgcga ataacaccgg tattaacacc cttgatgctt
    12361 atggccatgt aggttctccc taaccatttc tcaattaaat aattaatttt aatttataag
    12421 ccagataaat gggcttggta gtaatagttg ttaaaataac ataaatagcc gtgctcactc
    12481 tatataaaca gaaaagaaag gttaattatt ggtgttagct atataaaaag taacaacagc
    12541 aatgcatatg aataattaaa ggttatgcaa cgtgcaaaga ttaaatttcc cagtttaatg
    12601 acaggttgct gtacttgcgt ttgttgctct tgccggatgc ggcgtaaacg ccttatccgg
    12661 cctacagttc attgcaaatc cattcaattt caatgcacaa tgtaggcctg ataagcgtag
    12721 cgcatcaggc taatgtttaa cttccctgtt taatcagtta ctgctggcgt agctggagat
    12781 ccagcggcgt tttgctgggt tcgccgccga tttctcgcgc cagtttcggc accagataac
    12841 ccgacaccag tgtcagcaac tcacgcataa tctgccgtgc ttcgtcatca ctcaccataa
    12901 aatgcgccgc gccctgtact ttatcgagca catgcaggta atacggcatt acgccggcat
    12961 cgaacaacgc attactcagg tttgccagcg tttgtgcgtt atcgttcaca ccacgtaaca
    13021 gaacgctctg gttaagcagg gtgacaccga cacggcgcaa tttagccatc gcctgacgga
    13081 acgtttcatc tacctcattg gcatgattga tgtgattcac cagcaagatt tgcagcgtag
    13141 aacgggcaaa gcgttcaacc agcgcctcgg tgatacgtgc cgggatcaca atcggcagac
    13201 ggctgtgaat ccgcagacgt ttgatatgcg ggatggcttc cagttgtgtg agcaaccagt
    13261 ccagctcgtg atctttcgcc atcagcggat cgccgccgga gaaaatcatc tcgtccagtt
    13321 ccggatgcgc agcaacatac tcaagaacag tctgccagtt acgcttgttg ccctgatttt
    13381 cggcataggg gaagtggcga cggaagcaat agcggcaatt taccgcgcag ccgcctttga
    13441 ccagcaaaag cgcccggttg tggtatttat gcaacaaacc aggcactacg ctgtgctgtt
    13501 cttccagcgg gtcggtggag aatccggacg cgacgacaaa ctcatcttgc gaggtaagta
    13561 cctgacgcaa aagaggatcg tccggattgc ctttctccat gcgatcgata aatgagcggg
    13621 gcacacgcag ggcaaacagc tttttggcgc tgcgtccggc caacagtttt tcgtccgcgt
    13681 ctatattcaa aagacgcaga agttcatcag gatcggtcac aacatcggca agttgcgtta
    13741 accaatcttc tctggatggg gtatttaggg ttacaatatg cgccattttg tggcttagct
    13801 accaattaac aaatttcaga gggccttatg gcaacgtact atagcaacga ttttcgtgct
    13861 ggtcttaaaa tcatgttaga cggcgaacct tacgcggttg aagcgagtga attcgtaaaa
    13921 ccgggtaaag gccaggcatt tgctcgcgtt aaactgcgtc gtctgctgac cggtactcgc
    13981 gtagaaaaaa ccttcaaatc tactgattcc gctgaaggcg ctgatgttgt cgatatgaac
    14041 ctgacttacc tgtacaacga cggtgagttc tggcacttca tgaacaacga aactttcgag
    14101 cagctgtctg ctgatgcaaa agcaattggc gacaacgcta aatggctgct ggatcaggca
    14161 gagtgtatcg taactctgtg gaatggtcag ccgatctccg ttactccgcc gaacttcgtt
    14221 gaactggaaa tcgttgatac cgatccgggc ctgaaaggtg ataccgcagg tactggcggc
    14281 aaaccggcta ccctgtctac tggcgctgtg gttaaggttc cgctgttcgt acaaatcggc
    14341 gaagtcatca aagtggatac ccgctctggt gaatacgtct ctcgcgtgaa gtaatgcggt
    14401 tgtggtgcgg cctgcaggct gcaccatcac ttattcaggt cagagatgat gaaacgcctt
    14461 atcgttcttg ttttgcttgc cagcacgctg ctcacgggct gtaacaccgc tcgcggtttc
    14521 ggcgaagaca tcaaacatct cggcaactcc atctctcgcg ctgccagcta atttttcttc
    14581 tcttccgaaa aatcatcaga tttccgtcat ttttggcgat gttgtctatt attaatttgc
    14641 tataggcaaa cataaataac attacctaaa aggaagacgt tatggtgaag aagacaattg
    14701 cagcgatctt ttctgttctg gtgctttcaa cagtattaac tgcctgcaac accacgcgtg
    14761 gcgttggtga agacatttct gatggcggta acgcgatttc tggcgcagca acgaaagcgc
    14821 agcaatagca ataagcaata acggtacgac aggtatgtcg tgccgtttgt tttttctgcg
    14881 atagtcacta aggtaatagt tgaaattccc ctgccacctg gcaaaatatc cgttcaacca
    14941 tcagctttgc aggacgacct gcaaacgcct cttttcaccg gggacggccc caattctccg
    15001 gagcctgata tgtcctggat tatcttagtt attgctggtc tgctggaagt ggtatgggcc
    15061 gttggcctga aatataccca cggctttagt cgtttgacgc cgagtgttat taccgtgacg
    15121 gcgatgattg tcagtatggc gctacttgcc tgggcgatga aatcgttacc agtagggacg
    15181 gcttatgccg tgtggacggg tattggcgca gtcggcgcgg ctatcaccgg cattgtgctg
    15241 ctcggtgagt ccgctaaccc gatgcgcctg gcgagtctgg cgttaatcgt attggggatt
    15301 attggtctga aactcagcac tcactaacta ccgggctgct gtacccaaat aaacttactg
    15361 acatcaaacc cttcccgggt cgcgactgcc agcatctcct gtttcacttc gtcagaaatg
    15421 gttggcgtgc gggagagtat ccacaggtag tcgcggtccg ggccgcaaac cagcgcatgg
    15481 cggtattccc gatcgagtgc aataacgtta taaccgccat agaaaggacc aaagaatgac
    15541 actttcagcg cagcgcgagt tggtgcgccg gtaaagtacg ctttcccttc actctgctgc
    15601 cacattcctc tgtcagggtt atagccttta ttaatgacat tcaggccgcc gtcatcacgc
    15661 aggctgtatg ttgcggtgac tttttccagt ccacgttcaa aacggtgatc aaaacgggca
    15721 atctcatacc aggtaccgag ataacgtttg gcgtcgaaat tattcactac tgttacgcca
    15781 cgcggcggcg taggagaact gcaggcaacg accagaaatg cagctgtcgc tgcggcaacg
    15841 agagggagca ggcgcataaa tgtttcctta ctggtttttt tctaagtgta gatgacagca
    15901 aggaaaagcg cagaaaaggt ccgaaaattc ggacccgatg aaattttact gtagagcgtt
    15961 gagaatctgc caggcggcgg cgactctcgc tggattggga tagtttttgt tagccagcat
    16021 cactataccc agctcttttt ctggaataaa cgcgacatag ctaccaaatc cgccggttgc
    16081 ccctgtttta tgtacccatg atgcgcgtac tgcaggagtt gggggcgtaa tcgcttttac
    16141 ggggtgtgct gccagtgcaa ttttattgcc actgccgtta atgatgctgt caggatttac
    16201 cggccagtcc agcatttccc agcccaggcc ctgatacata tcgccggttt gccagtagcg
    16261 agattgtgcc agttgtatcc cttgctgaag tgttttgtcg ttgatatcac ggggattcat
    16321 attgcttcgt acccagcagg ccatatcttc aatggtcgac ttcacaccat aagtttcagc
    16381 atctaacgcc cctggcgaaa catgaactgc cttgccttcg cgatatcccc aggcgtaatt
    16441 cttttcttct gcgggcggta cattaatcca cgtatggttg agtttgagtg gctggaagac
    16501 acgtgtttgc atcgcctgct caaaactcaa accagacggc ttcacagcca gtgcgccgaa
    16561 caaaccgata ctggagttgg catacagacg ttgtgttcct ggcgcccatg caggctgcca
    16621 gttttgatag aagcgcagca agtcgcttga ggatttcacc tcatccggca cctgcaatgg
    16681 caggccgcca gcagtgtagg ttgcgagatg taatagtgtg atcccattcc actgtttagc
    16741 ggtaagttca ggccagtatt ttgttgtggg atcgcttaac ttgatttccc ctcgagcaat
    16801 agcgtcgcca ccaagcacgc ccgtaaatgt tttgctgacc gaacctaact caaacaacgt
    16861 ttgctgtgtg acgggctgct ttttggcgat gtccgcatag ccccaggtaa agtaataagg
    16921 tttaccctga taaattaccg ccaccgccat accggggatc ttttgttgct ctataagcgg
    16981 ggtaattgtg cgatgcacaa tatcgttgat ttgttgaggg gcagcaaatg tggagcaaga
    17041 ggcggtaatt aataaggcgc agagcgtcgt tttgaacata aggtctggtt tccatacaaa
    17101 acggcccgcc ataggcgggc cggatttaca ttggcgatac gttagattgt aacgatacca
    17161 atcagcgtga caactgtcag gatagcagcc agaccgtaga aaacccattt gcccgcaggc
    17221 acgtgaattt tcagatcgtg catcgcgtgg tgcatacggt gtaaaccaca ccacagcggc
    17281 agaacgatca tcaggaacag gaatacgcga ccaatgaagc tctgcgcgaa cgccagaacg
    17341 cgctcgtagc tcagcgcatc acccggaaac agccccagtg gcagcagaat acccaccagc
    17401 aggatcatca ccggcgcaat aattgcgctc cacataccac cggccccgaa gaggccccag
    17461 aataccggtt cgtcagaacg ctttggattt ggattaatca tctcaggctc cttaccagta
    17521 cagggcaaca aacaggatta cgatggtggc aaccacagtt accgcccaga gacttttgat
    17581 aattggctct ggtcccattt tttcgtcttt tacaatgata ttggccgctt tcggtgccag
    17641 ttcaaaccag gttttggtgt gcagcagagc tgccgccaga gtgatcaggt taatgatcac
    17701 gataaccggg ttttgtaaaa agtcgacgaa tcccgcccag gcttccgggc catttttcag
    17761 ggcaaacagc ccgaaaatca gttcaatgct gaaccacaca gccggaaccg ccgtgccttc
    17821 gcgcagcatg taaaagcgat aaaacggcaa ttttttccac caggtggacg tcattggccg
    17881 tacatacggt ttacgtttag tcgtcatgtt gcactcctta gcgtggtttc agggtcgcga
    17941 taagaaagtc tttcgaactt tctactttgc cctgctgaat ggccgcagcc ggatcgacgt
    18001 gtttcgggca gacttcggag caatagccca cgaaagtaca gctccatacg ccgttctggc
    18061 tgttcaactg cgccatacgc tccttcttac cgtggtcgcg gctatcttcg ttataacgat
    18121 gcgccagcgt aatggcagcc ggaccgatga actctgggtt caggccaaac tgcgggcacg
    18181 cggcgtagca cagaccacag ttgatgcaac cggagaactg gtgatacttt gccatctgcg
    18241 ccggggtctg gatgttagta ccctgatccg cggtgcggga gttgccgatg atgtacggtt
    18301 tgatcgcttc cagactttcg atgaagtggg tcatatcgac caccagatcg cgttcaatcg
    18361 ggaagttagc taacgcttca accttcatac cgtcggtgta atcacgcagg aaggttttac
    18421 atgccagttt tggcacgttg ttaaccatca tgccgcagga accacaaatc gccatacggc
    18481 aggaccagcg gtaactcagg tccggtgcca ggttgtcttt gatgtagccc agcgcatcca
    18541 gtaatgaggt agttgcgtca taaggcactt catagaatgc gctatgcggt gcggtatcga
    18601 cttccgggtt atagcgcacc acctcaattt tcaggttttt catctcagcc attcgccttc
    18661 tccttcttat tggctgcttc cgccttatcg gctgcatccg cttcgccacc gtaaacgcgt
    18721 ttagctggcg gcagcgtagt aatcttcacg tcgctgtact ccaggcgagt cgtgccatca
    18781 gcatcgcgga aggcgagggt gtgtttgagg aagttgacgt cgtcacgctc ggtgcaacct
    18841 tcgtccagac gctggtgtgc gccgcgggac tctttacgtg ccattgcgga gtgcgccata
    18901 cattcagcaa cgttcagacc gtggcccagt tcaatggtgt agagcaggtc ggtgttgaac
    18961 acgctggagg tgtcggtgat gcgcacgcgc ttgaagcgtt cctgcagctc tgccagcttg
    19021 tcgatggttt tctgcatcag ttccggcgta cggtagatac cgcaaccttc ttccattgcc
    19081 aggcccattt cgtcgcggat cttcgcccag ttttcgccgc catcctggtt aaccagatct
    19141 ttcagacgtt gttcaacgcc agctgcctgc gcttcaattg ccgcttcgtt gccattaccg
    19201 gcagttgctg cacgctctgt cgcttgttca ccggccagac ggccgaagac caccagttcc
    19261 gccagggagt tagaacccag acggtttgca ccgtgcagac caacagagga acattcaccc
    19321 acggcgaaca gacctttaat gcgggtttca cagttctgat cggtttcgat accgcccatg
    19381 gtgtagtgtg cggtcggacg taccggaatc ggttctttaa ccggatcgac gccaacgtac
    19441 gctttcgcca gttcgcagat gaacggcaga cgttcatgca gttttttctc gccgaggtga
    19501 cgcaagtcga gataaaccac atcgccacgc ggcgtggaga tggtgttgcc tttacgccat
    19561 tcgtgccaga aggcctgaga aactttgtcg cgtggaccca gttccatata tttgtttttc
    19621 ggctcgccca gcggagtttc cgggcccatg ccgtaatctt gcagataacg gtagccattt
    19681 ttgttgacca gaataccgcc ttcaccgcgg cagccttcgg tcatcaggat accggaacct
    19741 ggcagaccgg ttgggtgata ctgaacgaat tccatgtcac gcagcggaac gccgtggctt
    19801 agcgccatac ccataccgtc accggtaacg atgccgccgt tggtgttgta acgataaacg
    19861 cgacccgcac cgccagtagc cataacgacc gcgttagcac ggatctgcac cagcgtgcct
    19921 tccatcatgt tcattgctac cacgccgcga acatgaccat catcaaccag aatatccagc
    19981 acgaaatgtt cgtcaaaacg ctggatctgc gggaattgca gagaggtctg gaacagcgtg
    20041 tgcagcatat ggaagccggt cttatcggcg gcgaaccagg tgcgctcgat tttcatgccg
    20101 ccgaagcgac gtacgttgac gctaccatcc gggcgacggc tccatgggca cccccacagt
    20161 tccagttggg tcatttcggt tgggcagtgg tggacgaaat aatccacgac atcctgctca
    20221 cacaaccagt cgccacccgc tactgtatcg tgaaagtgat attcgaagct gtcatgatcc
    20281 tgcgcgacag cggcggagcc cccttctgca gcaacggtat ggctacgcat cgggtatact
    20341 tttgagatta gtgcgatttt tgcatttgga tttgcctgcg cggcagcaat tgcagcacgt
    20401 aatcccgcgc caccggcgcc tacaatggca agatcggctt gaaaggtttg cacgacattc
    20461 ctccagattg tttttatccc acagccccgt acttcagggt aagtgcctga aagttacggt
    20521 ctgcgaacgc tattccactg ctcctttata ggtacaacag tatagtctga tggataagtc
    20581 tgaaatttga cgagatcgat ttttttagtg cgcaagaggg ctaaattatc actgaagatg
    20641 attaatttaa ttactaaacc atcagatcgt gcttttttta gtcactgccc accgctgttt
    20701 gattcctgcg taaaatttgt ctcgccgtcg cgttgcgagt agacttcgtg cccttgtcaa
    20761 aaactggaga tttaactatg agcgaaacgg catcctggca gccgagcgca tccattccta
    20821 acttattaaa acgcgcggcg attatggcgg agatccgtcg tttctttgcc gatcgtggag
    20881 tgctggaggt ggagacgcct tgtatgagcc aggcgacggt aaccgatatt catttggtcc
    20941 cgtttgagac acgtttcgtt ggccccgggc attcgcaggg gatgaatctc tggttaatga
    21001 ccagcccgga ataccatatg aaacgcctgc tggttgccgg ttgtgggccg gtattccagc
    21061 tgtgccgcag cttccgtaat gaagagatgg ggcgttatca caaccctgag ttcactatgc
    21121 tggagtggta tcgaccgcac tatgatatgt accggttgat gaacgaggtg gacgatctct
    21181 tacaacaggt gctggactgc ccggcagcag aaagcctttc ttatcaacaa gctttcttgc
    21241 gttatctgga aattgacccg ctctctgccg acaaaacgca actgcgggaa gtcgcagcga
    21301 aactggattt gagcaatgtt gctgataccg aagaagaccg cgacacgctg ctacaattgc
    21361 tgtttacctt tggcgtagag ccaaatattg gcaaagaaaa accgaccttt gtgtaccact
    21421 ttccagccag ccaggcatca ctggcgcaaa tcagtaccga agatcatcgg gtcgctgaac
    21481 gctttgaggt ttattataaa ggtattgagc tggcgaatgg tttccatgaa ttgacggatg
    21541 cccgtgagca gcaacaacgc tttgaacaag ataaccgtaa gcgcgcggcg cgcggtttgc
    21601 cgcagcaccc cattgaccag aatctgattg aagccttgaa agtcggtatg cctgactgtt
    21661 ccggcgtggc attaggtgtt gatcgtctgg tgatgttggc gctgggcgcg gagacactgg
    21721 ctgaagtcat cgcctttagc gttgaccggg cataattctg aaaaattact gaattaacag
    21781 cgaagaatgg cgtgataagc gccattctgt agcatatgtt ttcatttttc cgttaaaggc
    21841 cacaatttaa gactggatat ttgatatcat ccaggtatca attctgtatt ggtttttacg
    21901 ctgcctgctc aatgttgcgc agtgcagttc agtgggcacg tgttatacac gcgctgaaat
    21961 gaaggatggt ttcatgcctc acacgataaa aaagatgagt ctgataggac tcatattgat
    22021 gatctttact tccgtatttg gatttgccaa tagcccatcg gcttattact taatgggtta
    22081 tagtgcgatt cccttttata tattttctgc attgttattc tttattccat tcgccttaat
    22141 gatggctgaa atgggagctg cttatcgcaa agaagaaggt ggtatctatt cctggatgaa
    22201 taatagtgtc ggaccacgtt ttgccttcat tggtacgttt atgtggtttt cctcttatat
    22261 catctggatg gtgagtacct ccgcgaaagt ttgggtaccg ttctcaacat tcctctatgg
    22321 tagcgacatg acccagcact ggcgtattgc cggactggag cctacgcagg tggttggtct
    22381 gctggcagta gcatggatga ttctggtcac cgtcgttgct tcaaagggga ttaataaaat
    22441 tgcccgcatt actgcggtgg gcggtattgc agtaatgtgt ctgaatttag tattgctgtt
    22501 agtaagcatt actattttgt tattaaatgg tgggcatttc gcgcaggata ttaatttcct
    22561 tgcatcaccg aacccaggtt atcagtccgg tctggcaatg ctatcgtttg tggtatttgc
    22621 tatttttgcc tatggcggaa ttgaagcggt tggtggtctg gtcgataaaa cggaaaatcc
    22681 agaaaagaac tttgccaaag gtattgtttt tgccgctatt gttatttcaa tcggttattc
    22741 gctggcaata tttttatggg gtgtcagcac aaactggcag caggtattaa gtaatggttc
    22801 cgttaacctc ggcaatatta cctatgtgct gatgaagagc ctcggggtga cgctgggtaa
    22861 cgcactgcat ttgtcacctg aagcgtcatt gtcgctgggt gtatggtttg cgcgtattac
    22921 cggactttcg atgttcctcg cttataccgg ggcgttcttt acgctttgct attcaccgct
    22981 gaaagccatc atccagggga cgccgaaagc gttgtggccg gaaccgatga cgcgcctgaa
    23041 tgcgatgggg atgccttcta tcgccatgtg gatgcagtgc gggttggtta ctgtcttcat
    23101 cctgctggtt tcgtttggtg gcggtaccgc atcggcgttc tttaacaagc tgacgctgat
    23161 ggcgaacgtg tctatgacgc ttccttacct gttcctcgcg ctggctttcc cattctttaa
    23221 agcacgtcag gatctcgaca gaccatttgt gattttcaaa acgcgtatgt cggcaatgat
    23281 tgcgacggtg gttgtcgtac tggtggtgac atttgcgaac gtcttcacca tcattcaacc
    23341 tgtggttgaa gccggagact gggacagcac attgtggatg attggcggcc ctgtcttctt
    23401 ctcgctgtta gcgatggcga tttaccagaa ctattgcagt cgcatggcga ataaacctga
    23461 gttagctctc gactgatcat atgaaatcct gcaactcatc gtctctccgg cgatgagttg
    23521 tcaggaagta atgcgtatgg atgatactct ccagggccgg tgataactga agatgatgtt
    23581 aagctgctaa atgagccacg ttgacatcat ttggcagctt catgcattac aaacttcccg
    23641 cctgacgacc tttgcccgca gaagttaatg ttctccccgt ttgcttaccg ttgaggcttt
    23701 ccagacgcat ctggaagggc gggaatggca tatcgatacc gtgggcgtgg aagcctgcca
    23761 gaatcagctg gtggatctca tggcgtatcg gcatacggtg acccatctca gcggcgtaaa
    23821 tacgcagctc gaaaatctga atcccctgtt gcagatccac caggaagact tccggtgccg
    23881 ggttgtcgat caccagcgag cagcgacgcg ctgcggtgag caggatttcc gtcacttctt
    23941 cgctattggc atcggcaggg gccggtatcg tcaacaccac gcgcgtgacc gagtcagaga
    24001 gcgaccagtt gataaactgc tcggtaataa acgccttgtt cggcacgatt atctctttac
    24061 ggtcccagtc gctgatggtg gtggcgcggg tgttaatttt cgtcacgcta ccggtaagat
    24121 cgcggatcgt taccgtatcg ccaatgcgaa tcggtttttc gaacaggata atcaggccag
    24181 agataaagtt ggcgaaaatc tcctgcaaac caaaaccgag accaacaccg agcgcggcaa
    24241 ccagccactg caatttcgac cactcaatac caatcatcga gaagccgacc agcccgccaa
    24301 tcagcatcag cagatatttg gtgatggtgg tgatggcgta gcccgtaccc ggcgttaaat
    24361 ccaggtgctg caaaatcgcc agttccagca gcgcgggcag gttgcgcacc agctgcgtgg
    24421 tgatgataaa caccagaatg gcaatcagca ccgcaccgag ggtaattggc tccagacttt
    24481 ctacgccctg taccgtggag gtgacatccc acagcgaaat attttcgagg aagccgaaag
    24541 cggaatggat ttctgaccac agcacaatga cagaaagcag ggcgatcaac atcaaaattg
    24601 agcgcaccag ccgcaaggat tgcgcactga tggcatcgag atcgacttcg ctttcatcga
    24661 cttcaattgc cccttccggg ctactgtgat gatgcgcttc ctcttcgcca cgcgcgcgtt
    24721 gcgctaacat ctctgcccgg cgatgcttcg cccggtcaaa cgccagcctg cgacgctgga
    24781 tcagcatcca gcggcggata acgtgataaa ccaccagtag caggaaccag atggcaaccg
    24841 aggtttcaag cctcgctaac agtgcctgcg ccgttgccag ataacccacc gctgacgcca
    24901 gaatggcaac cagtggtgcg ccaatcatca tgttccacag catatggttg gtaatgttgt
    24961 cgccgctgcc ctctttgttg aggtacagcg ggatcccggc ctttttcagg ctgagggtga
    25021 ccaccgccag cgcaccgcaa atgaggataa agcaaagccg tcccagcgaa ccggagaatt
    25081 cacggtcgtc gaggttatcg aacatcatca gcgccataat cagcggcaca ataagcccga
    25141 tgctcatcag gtagtagcgc atcccacggg aaacacgttc gcgcggccag ccaaaatgag
    25201 cgataaacaa gccgttcggg cgggcaaagg tggcgcaaat catcactacc cacagcagcg
    25261 gcacggtggc cgttacgcca tcgccaatcg cgaccgccag cggataaggc cacgcctcgc
    25321 gcaagccgta acccagcgtc atccacagca ccggcagcgg tgacgcgacg agaatcgacc
    25381 agaaaagagt gcgcaacgtc agccagaagt gatcctgagt cactttgccg actttcgccg
    25441 ccgaacgttc aagaaaacgg gtgaaatagc ggcgcgagta aatactgcaa ccgaccagaa
    25501 tcaacgcgcc aaacagcggc aaaatcgtct ctttgctggt cagcatcatc acactggctt
    25561 tgcccaactg actgaaggtg tccagcgaaa tgagacgacg cagatcctgg gcgatttcca
    25621 gcggccaggc gatggtcatc gggcgcacgt cagaggtcca gaacagatag cggtgcgttg
    25681 cttcgttcac ctctttcagc gcatcctcca gttgcccgtt ggagactttc agcttggtca
    25741 gttccagtag tagcgtgtcg ccaccctgca acaatgagtt cagcaactca cgctgagtgc
    25801 gcagttgtgc ttccagaata cggttttgct cggcggtcag cggctgaccg tcggcctgat
    25861 gaatttgccg tagcagcggc tgtttattaa gcagatcctc ataacgtaac cgttgcacac
    25921 gcaactgcgc catttcggta tcaagctgtt gtggtttcgg catttccggc agccgtgcca
    25981 cctgcgcccg caacgcttcg ccgagcaggt tggacgatcc cagccattgc gactgttcac
    26041 gcagcgtatt cagcgcctgc cgaacctgta acgtctggct ggtggcctgg cgctgttgcg
    26101 aggcaacgag atccatccgc tgcgcctgtt gattcagtgc cgccgatagt tcgcggttaa
    26161 ttttgaattg cgcgacgatg tctttcggca aatcggcgct gttttctgcc agcaattcgg
    26221 tactttccag cgcccgctcc gcctcaagct gacgttggct gttcaactga ttacgtaagg
    26281 cctgcaaata cgcatccagt tgctggctct ctttttccgc cagctctgag cgtaagcgcg
    26341 ctaattcctg acggttattg gcagacagct gcgccagttc cagttcatca acgagcgctt
    26401 tcaggcgtgc ggagtcagac tgcaacgcga aattttgtgc ctgattgagc ggggtattgc
    26461 cagtaagcgt tcccaggcgg cgctcgatct catttaactg acggcgggcg tcggtttgct
    26521 gttgcggcag ttgattcagc gaatcggcaa tctcgcgggc gcgctcctgc tcttgctggg
    26581 cctgacggct tttatccagc aactggctgc tgacctggag aatttcctga ttcagcgcgt
    26641 cggtagacat tcccggcgac acgctgcgcg gctcgtcacg catgttgttt aattgtgcgc
    26701 gcagagtagc ggagagtttc ggataattat cgataacttg ctgatattgt ttgatgcgct
    26761 caagggaacc ttttcgttcc tcaagcgcat ttaaggcaga ctggagcgcc tctacgactt
    26821 ccggctgtgc gggtttcgcc gcttttgcct gctccagttc ctgagtgatt tgtttgctat
    26881 cgggggccgt cgcggcgtac gccccccaac tgaggcacca ggccatcaga aaagtgataa
    26941 tcaggcgcac gtcagcgttt cctttgatgg attagacctg gtctttttta tcgtcaacca
    27001 atgggctggc gtcgtgttct gcttcgatct cttcagcagg aagtggggcg ggttcagcgt
    27061 ctggcgtaac aaaggtttcg gtagatactg ccagcggctg gccaattttc gtgacagaca
    27121 ggctttccag ttgctcaacc agattcactt tacccggtgc aaacaggttg ataacggtag
    27181 agccgagttt aaagcggccc atttcctggc ctttcagcag tgccacagaa ccgtcgtttt
    27241 ccccggcagg ccaggtccag cgcttgatga taccttcgcg cggcggcgta atggtgcccg
    27301 cccagaccgt ctcaatgctg cctacaatcg tcgccccgac cagaatctgc gccatcgggc
    27361 caaattcggt atcgaacagg caaatcacgc gttcgttacg ggcaaacaga ttcggcacgt
    27421 tctgagcggt gagatggtta acggagaaga gatcgcccgg cacgtagatc atctcacgca
    27481 gaataccgtt gcacggcatg tgtacgcgat ggtagtcacg cggggagagg taagtggtca
    27541 caaacgtacc gttgcggaac aggtccgcca tcagatagtt gcctgccagc agggcttcga
    27601 ggctgtagtt gtggcctttg gcttgcagga ttttattttc ttcgatttta cccaactggc
    27661 tgataacgcc atcggcaggc atgaccagga cattcggatc ggtatcgatt gggcgtactt
    27721 cgtcacgcag cggacggaca aagaattcgt taaaggtgcg gtagctggcg gtgtccggct
    27781 tttgcgcctc tttcatgtcg accttgtagt atttaacgaa cagatcgata accagttttg
    27841 tcagccatcc tgcccgcttg cttgcgcccc aacccgccag gcgagtaagc catagtttcg
    27901 gcagaatgta ctgtagcgaa agtttaaatg aatttaacaa ggtagcctcc aggccattgt
    27961 tttgtcgttc ctgatccggc caacatgccg gatcctgaaa aaaaggggac gattctaacg
    28021 acggttagct taattgtcag tcatccgtat cagaaaagtt tttacgcgtt tttacctgcg
    28081 ccatgctttc cagaatacgg tgatagtttt cgaaacgggt ttccgcgatt ttcccttcct
    28141 caaccgcttc ccggatagcg cagcccggat cggtatcgtg tttgcaatcg cgatatttac
    28201 acagacctaa atagtcatgg aattcgacaa agccctgagt gatttgttcc ggctccaggt
    28261 gccagaggcc gaactcacgc acaccagggg aatcaatcac atcaccgccg tgcgggaagt
    28321 gatacagccg agcggcggtc gtggtgtgct gaccgagccc cgagttgtca gagacatcgt
    28381 tggtcaggat ctctttttgc agccccagca acgcattcag caggctggat ttgccgacgc
    28441 cagactgccc ggcaaaaatg ctgatgcgcc cggtcaacgc ctcttccagc ggttttagcc
    28501 catcctgagt atggctggaa accatcaata cgcgataacc gatattgcgg tagatatcca
    28561 tctgctcgtt gacgaacgcc atgccttcgt cgtccagcag gtctatcttg ttgagcacaa
    28621 taatcggctc aatctgcaag gtttcgcagg ccaccaggta acggtcgata atattgagcg
    28681 acagctccgg caaaatggcg gagacaatga caatctggtc gatgttggcg gcaataggtt
    28741 ttacgccgtc gtagaaatcc ggacgcgtca acaccgaggt acgctcatgc accgcttcca
    28801 cgatcccttt gacatttacg ccttccgccg ccggtttacc cggacgccag actacgcggt
    28861 cgccggttac cagcgaacgg atggtacggc gaatattgca gcggtgaacg tcgccatcgg
    28921 cggattccac atcagcgtgc ataccaaagc ggctgatgac gataccttca tcaggctcgc
    28981 caaacagatt gtcgtcgtag tcgggcttct ccttagacgt tttaagacga cgctggtgat
    29041 tggcgttcac gcggcgctgc tggcctttgg agagtttatt tttactcaat cgtacagact
    29101 cctggtcgcc cctgatgggc aaaacatcta tgatacacgc aattgtggat caatatagtc
    29161 actgtgaatg ggtggaaaat agcatgagtg ccaatgaaaa caacctgatt tggatcgatc
    29221 ttgagatgac cggtctggat cccgagcgcg atcgcattat tgagattgcc acgctggtga
    29281 ccgatgccaa cctgaatatt ctggcagaag ggccgaccat tgcagtacac cagtctgatg
    29341 aacagctggc gctgatggat gactggaacg tgcgcaccca taccgccagc gggctggtag
    29401 agcgcgtgaa agcgagcacg atgggcgatc gggaagctga actggcaacg ctcgaatttt
    29461 taaaacagtg ggtgcctgcg ggaaaatcgc cgatttgcgg taacagcatc ggtcaggacc
    29521 gtcgtttcct gtttaaatac atgccggagc tggaagccta cttccactac cgttatctcg
    29581 atgtcagcac cctgaaagag ctggcgcgcc gctggaagcc ggaaattctg gatggtttta
    29641 ccaagcaggg gacgcatcag gcgatggatg atatccgtga atcggtggcg gagctggctt
    29701 actaccgcga gcattttatc aagctgtaaa atttttcctg gtcacgtaag cgccggaatc
    29761 cacttgcggc ggcgtgattt tgacgctaaa ttgaacgtct tgctgataat ttcagcactt
    29821 gagataaaaa cgcaaaaaaa acttttttgg ggggttgcag agggaaagat ttctcgtata
    29881 atgcgcctcc cgtaacgacg cagaaatgcg aaaattacga aagcaaaatt aagtagtacg
    29941 cgggaatagc tcagttggta gagcacgacc ttgccaaggt cggggtcgcg agttcgagtc
    30001 tcgtttcccg ctccaaaatt tgaaaagtgc tgcaaagcac a
//
LOCUS       DAZUDJ010000062        29947 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.062, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000062 DAZUDJ010000000
VERSION     DAZUDJ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29947
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.062"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            248..631
                     /gene="secE"
                     /locus_tag="ACHY1N_003602"
     CDS             248..631
                     /gene="secE"
                     /locus_tag="ACHY1N_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFS4045830.1"
                     /translation="MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            633..1178
                     /gene="nusG"
                     /locus_tag="ACHY1N_003603"
     CDS             633..1178
                     /gene="nusG"
                     /locus_tag="ACHY1N_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFS4045831.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEDLFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            1337..1765
                     /gene="rplK"
                     /locus_tag="ACHY1N_003604"
     CDS             1337..1765
                     /gene="rplK"
                     /locus_tag="ACHY1N_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFS4045832.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            1769..2473
                     /gene="rplA"
                     /locus_tag="ACHY1N_003605"
     CDS             1769..2473
                     /gene="rplA"
                     /locus_tag="ACHY1N_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFS4045833.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAD
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASVN"
     gene            2886..3383
                     /gene="rplJ"
                     /locus_tag="ACHY1N_003606"
     CDS             2886..3383
                     /gene="rplJ"
                     /locus_tag="ACHY1N_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFS4045834.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            3450..3815
                     /gene="rplL"
                     /locus_tag="ACHY1N_003607"
     CDS             3450..3815
                     /gene="rplL"
                     /locus_tag="ACHY1N_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFS4045835.1"
                     /translation="MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKALEEAGAEVEVK"
     gene            4135..8163
                     /gene="rpoB"
                     /locus_tag="ACHY1N_003608"
     CDS             4135..8163
                     /gene="rpoB"
                     /locus_tag="ACHY1N_003608"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004870488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFS4045836.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     EEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8240..12463
                     /gene="rpoC"
                     /locus_tag="ACHY1N_003609"
     CDS             8240..12463
                     /gene="rpoC"
                     /locus_tag="ACHY1N_003609"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFS4045837.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAK
                     TSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQI
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEA
                     PAAPQVTAEDASASLAELLNAGLGGSDNE"
     gene            complement(12704..13837)
                     /gene="thiH"
                     /locus_tag="ACHY1N_003610"
     CDS             complement(12704..13837)
                     /gene="thiH"
                     /locus_tag="ACHY1N_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HFS4045838.1"
                     /translation="MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMA
                     LLSPAASGYLEQLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQ
                     PLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDNWRVDCYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMD
                     ERQLVQTICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSAFSKTQPGGYADNHP
                     ELEQFSPHDDRRPEAVAAALTAQGLQPVWKDWDSYLGHASQRP"
     gene            complement(13834..14604)
                     /gene="thiG"
                     /locus_tag="ACHY1N_003611"
     CDS             complement(13834..14604)
                     /gene="thiG"
                     /locus_tag="ACHY1N_003611"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418418.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HFS4045839.1"
                     /translation="MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKR
                     VDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDA
                     RWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAK
                     AFRLAVEAGLLARQSGPGSRSHFAHATSPLTGFLEASA"
     gene            complement(14606..14806)
                     /gene="thiS"
                     /locus_tag="ACHY1N_003612"
     CDS             complement(14606..14806)
                     /gene="thiS"
                     /locus_tag="ACHY1N_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HFS4045840.1"
                     /translation="MQILFNDQPMQCAAGQTVHELLEQLDQRQAGAALAINQQIVPRE
                     QWAQHIVQDGDQILLFQVIAGG"
     gene            complement(14790..15545)
                     /gene="thiF"
                     /locus_tag="ACHY1N_003613"
     CDS             complement(14790..15545)
                     /gene="thiF"
                     /locus_tag="ACHY1N_003613"
                     /EC_number="2.7.7.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709786.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole biosynthesis adenylyltransferase ThiF"
                     /protein_id="HFS4045841.1"
                     /translation="MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAA
                     LYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDINSPKSQVSQQRLTQLNPDIQLTA
                     LQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMV
                     LTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGE
                     LRLFDGKSSQWRSLALRRASGCPVCGGSNADPV"
     gene            complement(15538..16173)
                     /gene="thiE"
                     /locus_tag="ACHY1N_003614"
     CDS             complement(15538..16173)
                     /gene="thiE"
                     /locus_tag="ACHY1N_003614"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709787.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HFS4045842.1"
                     /translation="MYQPDFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRR
                     DEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAG
                     LRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYP
                     TVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE"
     gene            complement(16173..18068)
                     /gene="thiC"
                     /locus_tag="ACHY1N_003615"
     CDS             complement(16173..18068)
                     /gene="thiC"
                     /locus_tag="ACHY1N_003615"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HFS4045843.1"
                     /translation="MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRV
                     PMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWID
                     ARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSL
                     GDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
                     LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEI
                     YLRKEEA"
     regulatory      complement(18149..18249)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(18301..18777)
                     /gene="rsd"
                     /locus_tag="ACHY1N_003616"
     CDS             complement(18301..18777)
                     /gene="rsd"
                     /locus_tag="ACHY1N_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HFS4045844.1"
                     /translation="MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQ
                     IMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA"
     gene            18872..19645
                     /gene="nudC"
                     /locus_tag="ACHY1N_003617"
     CDS             18872..19645
                     /gene="nudC"
                     /locus_tag="ACHY1N_003617"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000210 - NAD+ diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HFS4045845.1"
                     /translation="MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRAL
                     QIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCG
                     HEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE"
     gene            19685..20749
                     /gene="hemE"
                     /locus_tag="ACHY1N_003618"
     CDS             19685..20749
                     /gene="hemE"
                     /locus_tag="ACHY1N_003618"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HFS4045846.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVP
                     PEHAGVFVEAVHRLSEQYHR"
     gene            20759..21430
                     /gene="nfi"
                     /locus_tag="ACHY1N_003619"
     CDS             20759..21430
                     /gene="nfi"
                     /locus_tag="ACHY1N_003619"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312948.1"
                     /note="cleaves DNA at apurinic or apyrimidinic sites;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HFS4045847.1"
                     /translation="MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYILGFLSFREYPALLAAWEMLSQKPDLVFV
                     DGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRY
                     TANQP"
     gene            21473..22063
                     /gene="yjaG"
                     /locus_tag="ACHY1N_003620"
     CDS             21473..22063
                     /gene="yjaG"
                     /locus_tag="ACHY1N_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HFS4045848.1"
                     /translation="MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCQQTGFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPSADDFDLYGVYPAIDACVALSE
                     LVHSRLSGETLEHAVEVSKTSITTVAMLEMTQAGREMSDEELKENPAVEQEWDIQWEI
                     FRLLAECEERDIELIKGLRADLREAGESNIGIIFQQ"
     gene            22250..22522
                     /gene="hupA"
                     /locus_tag="ACHY1N_003621"
     CDS             22250..22522
                     /gene="hupA"
                     /locus_tag="ACHY1N_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein HU-alpha"
                     /protein_id="HFS4045849.1"
                     /translation="MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            22535..23230
                     /gene="yjaH"
                     /locus_tag="ACHY1N_003622"
     CDS             22535..23230
                     /gene="yjaH"
                     /locus_tag="ACHY1N_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709795.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HFS4045850.1"
                     /translation="MNSFNEGVVSPLLSFWRRSLMLAGALFLTACSHNSSLPPFTASG
                     FAEDQGAVRIWRKDSGDNVHLLAVFSPWRSGDTTTREYRWQGDNLTLININVYSKPPV
                     NIRARFDDRGDLSFMQRESDGEKQQLSNDQIDLYRYRADQIRQISDALRQGRVVLRQG
                     RWHAMEQTVTTCEGQTIKPDLDSQAIAHIERRQSRSSVDVSVAWLEAPEGSQLLLVAN
                     SDFCRWQPNEKTF"
     gene            complement(23232..23657)
                     /gene="zraP"
                     /locus_tag="ACHY1N_003623"
     CDS             complement(23232..23657)
                     /gene="zraP"
                     /locus_tag="ACHY1N_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HFS4045851.1"
                     /translation="MKRNTKIALVMMALSAMAMGSTSAFAHGGHGMWQQNAAPLTSEQ
                     QTAWQKIHNDFYAQSSALQQQLVTKRYEYNALLAANPPDSSKINAVAKEMENLRQSLD
                     ELRVKRDIAMAEAGIPRGTGMGMGYGGCGGGGHMGMGHW"
     gene            complement(23660..23788)
                     /locus_tag="ACHY1N_003624"
     CDS             complement(23660..23788)
                     /locus_tag="ACHY1N_003624"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045852.1"
                     /translation="MTRYPQQASHFYSFIMPDYPSYQRFIVGTEDAIPEVRQPLED"
     gene            23895..25271
                     /gene="zraS"
                     /locus_tag="ACHY1N_003625"
     CDS             23895..25271
                     /gene="zraS"
                     /locus_tag="ACHY1N_003625"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HFS4045853.1"
                     /translation="MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRETAA
                     ARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEEMAGQPGVRWFAVTDEQGTI
                     VMHSNSGMVGKQLYSPQEMQQLHPGDEEAWRRIDSADGEPVLEIYRQFQPMFAAGMHR
                     MRHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLASVLSFFWYRRY
                     LRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQL
                     AQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANSREIQLRF
                     TANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTVSESGAGVKISVTDSGKG
                     IAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGSTFTLWLPVN
                     ITRKDPQG"
     gene            25268..26593
                     /gene="zraR"
                     /locus_tag="ACHY1N_003626"
     CDS             25268..26593
                     /gene="zraR"
                     /locus_tag="ACHY1N_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HFS4045854.1"
                     /translation="MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQ
                     VREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALD
                     YLIKPLDFDNLQATLEKALAHTHSIDAETPAVTASQFGMVGKSSAMQHLLSEIALVAP
                     SEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQTISVDVR
                     LIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIP
                     LGQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(26590..27879)
                     /gene="purD"
                     /locus_tag="ACHY1N_003627"
     CDS             complement(26590..27879)
                     /gene="purD"
                     /locus_tag="ACHY1N_003627"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFS4045855.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQ
                     NVAIGVTDIPALLDFAQNEKIDLTIVGPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLE
                     GSKAFTKDFLARHKIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GDKDTGPNTGGMGAYSPAPVVTDDVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACEGKLDEKTSEWDERASLGV
                     VMAAGGYPGDYRTGDVIHGLPLEEVADGKVFHAGTKLADDEQVVTNGGRVLCVTALGH
                     TVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN"
     gene            complement(27891..29480)
                     /gene="purH"
                     /locus_tag="ACHY1N_003628"
     CDS             complement(27891..29480)
                     /gene="purH"
                     /locus_tag="ACHY1N_003628"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFS4045856.1"
                     /translation="MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLL
                     AEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVV
                     VNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEM
                     DDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVK
                     EFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAI
                     ISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRD
                     LGMVGAEELRVVTQRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEV
                     IAAADEHGIAMLFTDMRHFRH"
BASE COUNT         7024 a         7800 c         8242 g         6881 t
ORIGIN      
        1 gcaaaagttc tgagctaatt gccgataaca tttgacgcaa tgcgcactaa aagggcatca
       61 tttgatgccc tttttgcacg ctttcgtacc agaacctggc tcatcagtga ttttctttgt
      121 cataatcatt gctgagacag gctctgttga gggcgtataa tccgaaaagc taatacgcgt
      181 ttcgatttgg tttgcctcgc gatcgcgggg tgaaaatgtt tgtagaaaac ttctgacagg
      241 ttggtttatg agtgcgaata ccgaagctca aggaagcggg cgcggcctgg aagcgatgaa
      301 gtgggtcgtt gtggtggcat tgctcctggt ggcgattgtc ggcaactacc tttatcgcga
      361 cattatgctg ccgctgcgtg cgctggccgt agtaattctg attgctgcag cgggtggtgt
      421 cgcgctgtta acgacaaaag gtaaagctac cgttgctttt gcccgtgaag cgcgtaccga
      481 agtccgtaag gtcatttggc cgactcgcca ggaaacattg cacaccacgc tgattgtggc
      541 tgcggttacc gcagtaatgt cactgatcct gtggggactg gatggtattc tggttcgcct
      601 ggtatccttt atcactggcc tgaggttctg agatgtctga agctcctaaa aagcgctggt
      661 acgtcgttca ggcgttttcc ggttttgaag gccgcgtagc aacgtcgctg cgtgagcata
      721 tcaaattaca caacatggaa gatttgtttg gtgaagtcat ggtaccaacc gaagaagtgg
      781 ttgaaatccg tggcggtcag cgtcgcaaaa gcgaacgtaa attcttccct ggctacgtcc
      841 tcgttcagat ggtgatgaac gacgcgagct ggcacctggt gcgcagcgta ccgcgtgtga
      901 tgggcttcat cggcggtact tccgatcgtc ctgcgccaat cagcgataaa gaagtcgatg
      961 cgattatgaa ccgcctgcag caggttggtg ataagccgcg tccgaaaacg ctgtttgaac
     1021 cgggtgaaat ggtccgtgtt aatgatggtc cgttcgctga cttcaacggt gttgttgaag
     1081 aagtggatta cgagaaatct cgtctgaaag tgtctgtttc tatcttcggt cgtgcgaccc
     1141 cggtagagct ggacttcagc caggttgaaa aagcctaacc cagcgatcaa aaaagcggcg
     1201 atttaatcgt tgcacaaggc gtgagattgg aatacaattt cgcgcatttt gtttttatgg
     1261 gccttgcccg taaaacgatt ttttatatca cggggagcct ctcagaggcg ttattaccca
     1321 acttgaggaa tttataatgg ctaagaaagt acaagcctat gtcaagctgc aggttgcagc
     1381 tggtatggct aacccgagtc cgccagtagg tccggctctg ggtcagcagg gcgtaaacat
     1441 catggaattc tgcaaagcgt tcaacgcaaa aactgattcc atcgaaaaag gtctgccgat
     1501 tccggtagta atcaccgttt acgctgaccg ttctttcact ttcgttacca agaccccgcc
     1561 ggcagcagtt ctgctgaaaa aagcggctgg tatcaagtct ggttccggta agccgaacaa
     1621 agacaaagtg ggtaaaattt cccgcgctca gctgcaggaa atcgcgcaga ccaaagctgc
     1681 cgacatgact ggtgccgaca ttgaagcgat gactcgctcc atcgaaggta ctgcacgttc
     1741 catgggcctg gtagtggagg actaagaaat ggctaaactg accaagcgca tgcgtgttat
     1801 ccgcgagaaa gttgatgcaa ccaaacagta cgacatcaac gaagctatcg cactgctgaa
     1861 agagctggcg actgctaaat tcgtagaaag cgtggacgta gctgttaacc tcggcatcga
     1921 cgctcgtaaa tctgaccaga acgtacgtgg tgcaactgta ctgccgcacg gtactggccg
     1981 ttccgttcgc gtagccgtat ttacccaagg tgcaaacgct gaagctgcta aagctgcagg
     2041 cgcagaactg gtaggtatgg aagatctggc tgaccagatc aagaaaggcg aaatgaactt
     2101 tgacgttgtt attgcttctc cggatgcaat gcgcgttgtt ggccagctgg gccaggttct
     2161 gggtccgcgc ggcctgatgc caaacccgaa agtgggtact gtaacaccga acgttgctga
     2221 agcggttaaa aacgctaaag ctggccaggt tcgttaccgt aacgacaaaa acggcatcat
     2281 ccacaccacc atcggtaaag tggactttga cgctgacaaa ctgaaagaaa acctggaagc
     2341 tctgctggtt gcgctgaaaa aagcaaaacc gactcaggcg aaaggcgtgt acatcaagaa
     2401 agttagcatc tccaccacca tgggtgcagg tgttgcagtt gaccaggctg gcctgagcgc
     2461 ttctgtaaac taatgccttt acgtgggcgg tgattttgtc tacaatctta cccccacgta
     2521 taatgcttaa tgcagacgta tatccgagat attcgggttg tggcaaggcg gcaactgagt
     2581 gagtcgccag gagcatagct aactatgtga ctggtgcgaa tgaaggaagc caacgccgcc
     2641 acaagttgaa tagcgacgga tagaaaagat ttgttcgttg gagcctggcc tatccaggcc
     2701 tccgtcgaag accgcaggag tttcgcaaga aacttaatcc cctgcgtaga cggtgacaga
     2761 acgctaagat tattctttta tattctggct tgtttctgct caccgtaatt aagacgctct
     2821 ctccgtttgg aggagtgaag tgagttccag agattttctc tggcaaacat ccaggagcaa
     2881 agctaatggc tttaaatctt caagacaaac aagcgattgt tgctgaagtc agcgaagtag
     2941 ccaaaggcgc gctgtctgca gtagttgcgg attcccgtgg cgtaactgta gataaaatga
     3001 ctgaactgcg taaagcaggt cgcgaagctg gcgtatacat gcgtgttgtt cgtaacaccc
     3061 tgctgcgccg tgctgttgaa ggtactccgt tcgagtgcct gaaagacgcg tttgttggtc
     3121 cgaccctgat tgcatactct atggaacacc cgggcgctgc tgctcgtctg ttcaaagagt
     3181 tcgcgaaagc gaatgcaaaa tttgaggtca aagccgctgc ctttgaaggt gagctgatcc
     3241 cggcgtctca gatcgaccgc ctggcaactc tgccgaccta cgaagaagca attgcacgcc
     3301 tgatggcaac catgaaagaa gcttcggctg gcaaactggt tcgtactctg gctgctgtac
     3361 gcgatgcgaa agaagctgct taatcgcagt tatcttttta acgcattcgc ttacgtataa
     3421 acttattctg atattcagga acaatttaaa tgtctatcac taaagatcaa atcattgaag
     3481 cagttgcagc tatgtctgta atggacgttg tagaactgat ctctgcaatg gaagaaaaat
     3541 tcggtgtttc cgctgctgct gctgtagctg tagctgctgg cccggttgaa gctgctgaag
     3601 aaaaaactga attcgacgta attctgaaag ctgctggcgc taacaaagtt gctgttatca
     3661 aagcagtacg tggcgcaact ggcctgggtc tgaaagaagc taaagacctg gtagaatctg
     3721 caccggctgc tctgaaagaa ggcgtgagca aagacgacgc agaagcactg aaaaaagctc
     3781 tggaagaagc tggcgctgaa gttgaagtta aataagccaa cccttccggt tgcagcctga
     3841 gaaatcaggc tgatggctgg tgacttttta gtcaccagcc tttttgcgct gtaaggcgcc
     3901 agtagcgttt cacactgttt gactactgct gtgcctttca atgcttgttt ctatcgacga
     3961 cttaatatac tgcgacagga cgtccgttct gtgtaaatcg caatgaaatg gtttaagcgt
     4021 gatagcaaca ggcattgcgg aaagtgttcc attttccggt caacaaaata gtgttgcaca
     4081 aactgtccgc tcaatggaca gatgggtcga cttgtcagcg agctgaggaa ccctatggtt
     4141 tactcctata ccgagaaaaa acgtattcgt aaggattttg gtaaacgtcc acaagttctg
     4201 gatgtacctt atctcctttc tatccagctt gactcgtttc agaaatttat cgagcaagat
     4261 cctgaagggc agtatggtct ggaagctgct ttccgttccg tattcccgat tcagagctac
     4321 agcggtaatt ccgagctgca atacgtcagc taccgccttg gcgaaccggt gtttgacgtc
     4381 caggaatgtc aaatccgtgg cgtgacctat tccgcaccgc tgcgcgttaa actgcgtctg
     4441 gtgatctatg agcgcgaagc gccggaaggc accgtaaaag acattaaaga acaagaagtc
     4501 tacatgggcg aaattccgct catgacagac aacggtacct ttgttatcaa cggtactgag
     4561 cgtgttatcg tttcccagct gcaccgtagt ccgggcgtct tctttgactc cgacaaaggt
     4621 aaaacccact cttcgggtaa agtgctgtat aacgcgcgta tcatccctta ccgtggttcc
     4681 tggctggact tcgaattcga tccgaaggac aacctgttcg tacgtatcga ccgtcgccgt
     4741 aaactgcctg cgaccatcat tctgcgcgcc ctgaactaca ccacagagca gatcctcgac
     4801 ctgttctttg aaaaagttat ctttgaaatc cgtgataaca agctgcagat ggaactggtg
     4861 ccggaacgcc tgcgtggtga aaccgcatct tttgacatcg aagctaacgg taaagtgtac
     4921 gtagaaaaag gccgccgtat cactgcgcgc cacattcgcc agctggaaaa agacgacgtc
     4981 aaactgatcg aagtcccggt tgagtacatc gcaggtaaag tggttgctaa agactatatt
     5041 gatgagtcta ccggcgagct gatctgcgca gcgaacatgg agctgagcct ggatctgctg
     5101 gctaagctga gccagtctgg tcacaagcgt atcgaaacgc tgttcaccaa cgatctggat
     5161 cacggcccat atatctctga aaccttacgt gtcgacccaa ctaacgaccg tctgagcgca
     5221 ctggtagaaa tctaccgcat gatgcgccct ggcgagccgc cgactcgtga agcagctgaa
     5281 agcctgttcg agaacctgtt cttctccgaa gaccgttatg acttgtctgc ggttggtcgt
     5341 atgaagttca accgttctct gctgcgcgaa gaaatcgaag gttccggtat cctgagcaaa
     5401 gacgacatca ttgatgttat gaaaaagctc atcgatatcc gtaacggtaa aggcgaagtc
     5461 gatgatatcg accacctcgg caaccgtcgt atccgttccg ttggcgaaat ggcggaaaac
     5521 cagttccgcg ttggcctggt acgtgtagag cgtgcggtga aagagcgtct gtctctgggc
     5581 gatctggata ccctgatgcc tcaggatatg atcaacgcca agccgatttc cgcagcagtg
     5641 aaagagttct tcggttccag ccagctgtct cagtttatgg accagaacaa cccgctgtct
     5701 gagattacgc acaaacgtcg tatctccgca ctcggcccag gcggtctgac ccgtgaacgt
     5761 gcaggcttcg aagttcgaga cgtacacccg actcactacg gtcgcgtatg tccaatcgaa
     5821 acccctgaag gtccgaacat cggtctgatc aactctctgt ccgtgtacgc acagactaac
     5881 gaatacggct tccttgagac tccgtatcgt aaagtgaccg acggtgttgt aactgacgaa
     5941 attcactacc tgtctgctat cgaagaaggc aactacgtta tcgcccaggc gaactccaac
     6001 ctggatgaag aaggccactt cgtagaagac ctggtaactt gccgtagcaa aggcgaatcc
     6061 agcttgttca gccgcgacca ggttgactac atggacgtat ccacccagca ggtggtatcc
     6121 gtcggtgcgt ccctgatccc gttcctggaa cacgatgacg ccaaccgtgc attgatgggt
     6181 gcgaacatgc aacgtcaggc cgttccgact ctgcgcgctg ataagccgct ggttggtact
     6241 ggtatggaac gtgctgttgc cgttgactcc ggtgtaactg cggtagctaa acgtggtggt
     6301 gtcgttcagt acgtggatgc ttcccgtatc gttatcaaag ttaacgaaga cgagatgtat
     6361 ccgggtgaag caggtatcga catctacaac ctgaccaaat acacccgttc taaccagaac
     6421 acctgtatca accagatgcc gtgtgtgtct ctgggtgaac cggttgaacg tggcgacgtg
     6481 ctggcagacg gtccgtccac cgacctcggt gaactggcgc ttggtcagaa catgcgcgta
     6541 gcgttcatgc cgtggaatgg ttacaacttc gaagactcca tcctcgtatc cgagcgtgtt
     6601 gttcaggaag accgtttcac caccatccac attcaggaac tggcgtgtgt gtcccgtgac
     6661 accaagctgg ggccggaaga gatcaccgct gacatcccga acgtgggtga agctgcgctc
     6721 tccaaactgg atgaatccgg tatcgtttac attggtgcgg aagtgaccgg tggcgacatt
     6781 ctggttggta aggtaacgcc gaaaggtgaa actcagctga ccccagaaga aaaactgctg
     6841 cgtgcgatct tcggtgagaa agcctctgac gttaaagact cttctctgcg cgtaccaaac
     6901 ggtgtatccg gtacggttat cgacgttcag gtctttactc gcgatggcgt agaaaaagac
     6961 aaacgtgcgc tggaaatcga agaaatgcag ctcaaacagg cgaagaaaga cctgtctgaa
     7021 gaactgcaga tcctcgaagc gggtctgttc agccgtatcc gtgctgtgct ggtagccggt
     7081 ggcgttgaag ctgagaagct cgacaaactg ccgcgcgatc gctggctgga gctaggcctg
     7141 acagacgaag agaaacaaaa tcagctggaa cagctggctg agcagtatga cgaactgaaa
     7201 cacgagttcg agaagaaact cgaagcgaaa cgccgcaaaa tcacccaggg cgacgatctg
     7261 gcaccgggcg tgctgaagat tgttaaggta tatctggcgg ttaaacgccg tatccagcct
     7321 ggtgacaaga tggcaggtcg tcacggtaac aagggtgtaa tttctaagat caacccgatc
     7381 gaagatatgc cttacgatga aaacggtacg ccggtagaca tcgtactgaa cccgctgggc
     7441 gtaccgtctc gtatgaacat cggtcagatc ctcgaaaccc acctgggtat ggctgcgaaa
     7501 ggtatcggcg acaagatcaa cgccatgctg aaacagcagc aagaagtcgc gaaactgcgc
     7561 gaattcatcc agcgtgcgta cgatctgggc gctgacgttc gtcagaaagt tgacctgagt
     7621 accttcagcg atgaagaagt tatgcgtctg gctgaaaacc tgcgcaaagg tatgccaatc
     7681 gcaacgccgg tgttcgacgg tgcgaaagaa gcagaaatta aagagctgct gaaacttggc
     7741 gacctgccga cttccggtca gatccgcctg tacgatggtc gcactggtga acagttcgag
     7801 cgtccggtaa ccgttggtta catgtacatg ctgaaactga accacctggt cgacgacaag
     7861 atgcacgcgc gttccaccgg ttcttacagc ctggttactc agcagccgct gggtggtaag
     7921 gcacagttcg gtggtcagcg tttcggggag atggaagtgt gggcgctgga agcatacggc
     7981 gcagcataca ccctgcagga aatgctcacc gttaagtctg atgacgtgaa cggtcgtacc
     8041 aagatgtata aaaacatcgt ggacggcaac catcagatgg agccgggcat gccagaatcc
     8101 ttcaacgtat tgttgaaaga gattcgttcg ctgggtatca acatcgaact ggaagacgag
     8161 taattctcgc tcaaacaggt cactgctgtc ggggtaaaac ccggcagcgg attgtgctaa
     8221 ctccgacggg agcaaatccg tgaaagattt attaaagttt ctgaaagcgc agactaaaac
     8281 cgaagagttt gatgcgatca aaattgctct ggcttcgcca gacatgatcc gttcatggtc
     8341 tttcggtgaa gttaaaaagc cggaaaccat caactaccgt acgttcaaac cagaacgtga
     8401 cggccttttc tgcgcccgta tctttgggcc ggtaaaagat tacgagtgcc tgtgcggtaa
     8461 gtacaagcgc ctgaaacacc gtggcgtcat ctgtgagaag tgcggcgttg aagtgaccca
     8521 gactaaagta cgccgtgagc gtatgggcca catcgaactg gcttccccga ctgcgcacat
     8581 ctggttcctg aaatcgctgc cgtcccgtat cggtctgctg ctcgatatgc cgctgcgcga
     8641 tatcgaacgc gtactgtact ttgaatccta tgtggttatc gaaggcggta tgaccaacct
     8701 ggaacgtcag cagatcctga ctgaagagca gtatctggac gcgctggaag agttcggtga
     8761 cgaattcgac gcgaagatgg gtgcggaagc aatccaggct ctgctgaaga gcatggatct
     8821 ggagcaagag tgcgaacagc tgcgtgaaga gctgaacgaa accaactccg aaaccaagcg
     8881 taaaaagctg accaagcgta tcaaactgct ggaagcgttc gttcagtctg gtaacaaacc
     8941 agagtggatg atcctgaccg ttctgccggt actgccgcca gatctgcgtc cgctggttcc
     9001 gctggatggt ggtcgtttcg cgacttctga cctgaacgat ctgtatcgtc gcgtcattaa
     9061 ccgtaacaac cgtctgaaac gtctgctgga tctggctgcg ccggacatca tcgtacgtaa
     9121 cgaaaaacgt atgctgcagg aagcggtaga cgccctgctg gataacggtc gtcgcggtcg
     9181 tgcgatcacc ggttctaaca agcgtcctct gaaatctttg gccgacatga tcaaaggtaa
     9241 acagggtcgt ttccgtcaga acctgctcgg taagcgtgtt gactactccg gtcgttctgt
     9301 aatcaccgta ggtccatacc tgcgtctgca tcagtgcggt ctgccgaaga aaatggcgct
     9361 ggagctgttc aaaccgttca tctacggcaa gctggaactg cgtggtcttg ctaccaccat
     9421 taaagctgcg aagaaaatgg ttgagcgcga agaagctgtc gtttgggata tcctggacga
     9481 agttatccgc gaacacccgg tactgctgaa ccgtgcaccg actctgcacc gtctgggtat
     9541 ccaggcattt gaaccggtac tgatcgaagg taaagctatc cagctgcacc cgctggtttg
     9601 tgcggcatat aacgccgact tcgatggtga ccagatggct gttcacgtac cgctgacgct
     9661 ggaagcccag ctggaagcgc gtgcgctgat gatgtctacc aacaacatcc tgtccccggc
     9721 gaacggcgaa ccaatcatcg ttccgtctca ggacgttgtt ctgggtctgt actatatgac
     9781 ccgtgactgt gttaacgcca aaggcgaagg catggtgctg actggcccga aagaagcaga
     9841 acgtctgtat cgctctggtc tggcttctct gcatgcgcgc gttaaagtgc gtatcaccga
     9901 gtatgaaaaa gatgcaaacg gtgaattagt agcgaaaacc agcctgaaag acacgactgt
     9961 tggccgtgcc attctgtgga tgattgtacc gaaaggtctg ccttactcca tcgtcaacca
    10021 ggcgctgggt aaaaaagcaa tctccaaaat gctgaacacc tgctaccgca ttctcggtct
    10081 gaaaccgacc gttatttttg cggaccagat catgtacacc ggcttcgcct atgcagcgcg
    10141 ttctggtgca tctgttggta tcgatgacat ggtcatcccg gagaagaaac acgaaatcat
    10201 ctccgaggca gaagcagaag ttgctgaaat tcaggagcag ttccagtctg gtctggtaac
    10261 tgcgggcgaa cgctacaaca aagttatcga tatctgggct gcggcgaacg atcgtgtatc
    10321 caaagcgatg atggataacc tgcaaactga aaccgtgatt aaccgtgacg gtcaggaaga
    10381 gaagcaggtt tccttcaaca gcatctacat gatggccgac tccggtgcgc gtggttctgc
    10441 ggcacagatt cgtcagcttg ctggtatgcg tggtctgatg gcgaagccgg atggctccat
    10501 catcgaaacg ccaatcaccg cgaacttccg tgaaggtctg aacgtactcc agtacttcat
    10561 ctccacccac ggtgctcgta aaggtctggc ggataccgca ctgaaaactg cgaactccgg
    10621 ttacctgact cgtcgtctgg ttgacgtggc gcaggacctg gtggttaccg aagacgattg
    10681 tggtacccat gaaggtatca tgatgactcc ggttatcgag ggtggtgacg ttaaagagcc
    10741 gctgcgcgat cgcgtactgg gtcgtgtaac tgctgaagac gttctgaagc cgggtactgc
    10801 tgatatcctc gttccgcgca acacgctgct gcacgaacag tggtgtgacc tgctggaaga
    10861 gaactctgtc gacgcggtaa aagtacgttc tgttgtatct tgtgacaccg actttggtgt
    10921 atgtgcgcac tgctacggtc gtgacctggc gcgtggccac atcatcaaca aaggtgaagc
    10981 aatcggtgtt atcgcggcac agtccatcgg tgaaccgggt acacagctga ccatgcgtac
    11041 gttccacatc ggtggtgcgg catctcgtgc ggctgctgaa tccagcatcc aggtgaaaaa
    11101 caaaggtagc atcaagctca gcaacgtgaa gtcggttgtg aactccagcg gtaaactggt
    11161 tatcacttcc cgtaacaccg aactgaaact gatcgacgaa ttcggtcgta ccaaagaaag
    11221 ctacaaagtg ccttacggtg cggtactggc gaaaggcgat ggcgaacagg ttgctggcgg
    11281 cgaaaccgtt gcaaactggg acccgcacac catgccggtt atcaccgaag taagcggttt
    11341 tgtacgcttt actgacatga tcgacggcca gaccattact cgtcagaccg acgaactgac
    11401 cggtctgtct tcgctggtgg ttctggattc cgcagaacgt accgcaggtg gtaaagatct
    11461 gcgtccggca ctgaaaatcg ttgatgctca gggtaacgac gttctgatcc ctggtaccga
    11521 tatgcctgcg cagtacttcc tgccgggtaa agcgattgtt cagctggaag atggcgtaca
    11581 gatcagctct ggtgacaccc tggcgcgtat tccgcaggaa tccggcggta ccaaggacat
    11641 caccggtggt ctgccacgcg ttgcggacct gttcgaagca cgtcgtccga aagagccggc
    11701 aatccttgct gaaatcagcg gtatcgtttc cttcggtaaa gaaaccaaag gtaaacgtcg
    11761 tctggttatc accccggtag acggtagcga tccgtacgaa gagatgattc cgaaatggcg
    11821 tcagctcaac gtgttcgaag gtgaacgtgt agaacgtggt gacgtaattt ccgacggtcc
    11881 ggaagcgccg cacgacattc tgcgtctgcg tggtgttcat gctgtgactc gttacatcgt
    11941 taacgaagta caggacgtat accgtctgca gggcgttaag attaacgata aacacatcga
    12001 agttatcgtt cgtcagatgc tgcgtaaagc taccatcgtt aacgcgggca gctccgactt
    12061 cctggaaggc gaacaggttg aatactctcg cgtcaagatc gcaaaccgcg aactggaagc
    12121 gaacggcaaa gtgggtgcaa cttactcccg cgatctgctg ggtatcacca aagcgtctct
    12181 ggcaaccgag tccttcatct ccgcggcatc gttccaggag accactcgcg tgctgaccga
    12241 agcagccgtt gcgggcaaac gcgacgaact gcgcggcctg aaagagaacg ttatcgtggg
    12301 tcgtctgatc ccggcaggta ccggttacgc gtaccaccag gatcgtatgc gtcgccgtgc
    12361 tgcgggtgaa gctccggctg caccgcaggt gactgccgaa gacgcatctg ccagcctggc
    12421 agaactgctg aacgcaggtc tgggcggttc tgataacgag taatcgttaa tccgcaaata
    12481 acgtaaaaac ccgcttcggc gggttttttt atgggtgtta ttcagagggc aaattcttca
    12541 cggaattttt aagaaaggca gggcgaaacg aggaagaagc ttttcgccct ggacaacatt
    12601 cctgctgacg gaactaccat aaaaaaacag aacgctttca acaaccttgc gtttttcatc
    12661 ttccgtagcg gctcggaata aatttacgtt gttacattct gtctcatggc ctttgcgagg
    12721 cgtgtcccag atagctgtcc cagtctttcc ataccggctg caaaccctga gcggttaacg
    12781 cggccgcaac tgcttctggt ctgcgatcgt cgtgcggtga gaactgttcc agctcggggt
    12841 gattgtcggc atagccacct ggctgcgttt tcgaaaaagc gctgacgtta ttaattgcca
    12901 gcggaatcac gcgatcgcga aaccacggtg attcccgcgt ggagagtgag agttcaatct
    12961 ccggtgcaag cagtcggaag gcgcagatgg tttgcactaa ctggcgttca tccataatcg
    13021 acgcaggctc aatgccgcca gtacacgggc gcaggcgcgg aaaggagaca gagtaacggc
    13081 tttgccagta atgctgttgc agccatagca aatgttcggc aaccatatag cagtcaacgc
    13141 gccagttgtc ggaaaggcca attagcgcgc cgaggcctat cttatcaatc cccgcacgcc
    13201 ccagccgatc cggcgtttcc agccgccaga agaagtcctg ttttttgcct ttcaaatgat
    13261 ggcgggcata agtcgcctcg tgatatgtct cctgataaac catcacgcca tccagaccaa
    13321 gctgctttaa ctcggcgtat tccgtctccg ccagcggttg cacttccatt tgtagtgaag
    13381 agaactgttc acgcagggcg gggagatgac gacgaaagta atccatcccc actttcgcct
    13441 gatgttcacc agtgactaat agcagatgtt caaagcccat ctcccgtata gcggcgcttt
    13501 ccctggcaat atccgcttca tccagcgttt tgcgtttgat gcgattactc atggaaaatc
    13561 cgcagtacgt gcagtcgtta gcgcaaagat tggaaagata aagcgggacg tagaaactaa
    13621 ctgtgttgcc aaatcgctga cgggtcagac gctgcgcccg ttgggccagt tgttccagat
    13681 agccactggc ggctggcgat aacagcgcca tcatatcgtc gcgggtgagt tgcgaggcat
    13741 ttagcgcccg ttctacgtca gcagccgttt tgccgttgat acgcaggcgg atgtcgtccc
    13801 agtccagttg tcgccagcga tcgctgaagg ttttcatgcc gatgcctcca gaaatccagt
    13861 cagcgggctg gtggcatgag caaaatgact gcggctgccc ggtccggact gacgtgccag
    13921 caggcctgct tctaccgcca gacgaaatgc cttcgccatg ttgacgggat cgtccgcgac
    13981 ggcaattgcc gtattcacta acaccgcgtc ggcccccatt tccagcgcct gcgcggcatg
    14041 gctgggaacg ccgatgccag catcgacaac caccggcact gtggcctgct ggataataat
    14101 ctccagcatg gcgcgggttt ccagtccctg attcgagcca atcggcgcgc cgagcggcat
    14161 caccgctgca cagccgactt cttccagacg tttacacaat accggatcgg ccccgcagta
    14221 aggcagcacg acaaatccct gttgtaccag cgtttcggcg gctttcaggg tttcgatggg
    14281 atcgggcaac agccagcggg cgtcagggtg aatctctaat tttaaccagt ttgtgcctaa
    14341 cgcttcacga gccagatggg cggcgaaaat ggcttcttcc gctgttttcg ccccggatgt
    14401 atttggcagc agggtcacac ccgccgcgat aagcggttcg aggatagcgt cgttgtgctg
    14461 gcgcaagtcg acacgtttca tcgccagtgt caccagctgg ctgccggaag cgcggatcgc
    14521 ctccaccatc agttgtgaag aagcgaattt ccctgtgccg gtaaacagat gtgaatcaaa
    14581 cgttttgtcc gcaatacgta acatttcaac cccctgcaat aacctgaaaa agcaggatct
    14641 ggtcgccatc ctgcacgata tgttgcgccc actgctcacg cgggacgatt tgctgattaa
    14701 tcgccagagc cgcgcccgct tgtcgttggt cgagttgctc cagtagttcg tgaacagttt
    14761 gcccggcggc gcactgcatc ggttgatcgt taaacaggat ctgcattgct tcctccgcat
    14821 accgggcaac cactggcgcg gcgcaacgcc aggctgcgcc actggctcga tttaccgtcg
    14881 aacagtcgga gttctcccgc aggtgtctct ataccgctta ataacttaat ggcttccagt
    14941 gcctgcaaag tgcccataac cccgaccacc gggccaacca cgcccgccgt gcggcagttg
    15001 cgttctggct cctggttatc tggccacagg cagcggtaac acccctgctc ccagggcggc
    15061 gtcagtacca tcaactgacc gccaaatccg accgcgctgg cggtgataag cggcgtgttg
    15121 agtgccacgc aggcggcatt aatctcctgg cgagtcgcca tattgtcggt acagtcgagc
    15181 accacatcgg cccgtgcaac cgcatctttt aacgcctcac ccgttaaccg ttgttgtaat
    15241 gctgtcagtt gaatgtcggg attcaactgt gtcagtcgct gttggctgac ctgcgatttc
    15301 gggctgttga tatcttcagt ggtaaagagg atttgtcgtt gcagattgct taaatgcaca
    15361 tcgtcgtcat ctgccagtac cagcgtcccg acgccagcgc ccgccaggta cagcgcagca
    15421 ggtgtaccca gcccgcccag accgataatc agcacctggc tgtcgagcag tttttgctgc
    15481 ccgtccagag cgatatcgtc gagcaggatt tggcggctat aacgcataaa gtcacggtca
    15541 ttcatcgcca actcctgcaa tttccagcaa ctgtgccgtt gccaaacgcc agtctgcagc
    15601 ttgagtaatg gcgctgacga cggcgatact gccgacaccc gttgctatca ccgcaggcgc
    15661 gcgtgccaga ctgataccgc caatcgccac ggtgggataa tccgccagtc gctcaacatg
    15721 ccgtgccagc tgttccagcc cctgcggtgc agaaggcatc tgtttggttt gcgtcgggaa
    15781 cacatgtccc agcgcgatat aagaggggcg tgctgccagc gcgacgtcga tttccatatc
    15841 gtcatgtgtc gaaacgccca gccgcaggcc tgccgcgcgg atggcattga gatcggtggc
    15901 ttgcaaatct tcctgcccca aatggacgcc atacgcctga tgcttgatcg ccagccgcca
    15961 gtaatcgttg ataaacaatc gcgcgttata gcggcggccc agcgcaattg ccgccacgac
    16021 atcggcttcc acctcttcat cgcgccgatc tttgatgcgt agctggagag tacgtacgcc
    16081 tgcatccaac agacgttcga tccactgtac gctgtccacc accgggtaca gtcctaaacg
    16141 aaaaggtaca ggaggaaaat caggctgata catcacgctt cctccttacg caggtagatt
    16201 tctccgcctc tggcacggaa gttctccgac atatccgcca ttcccatttc aatagtttgc
    16261 gtggcggcgt aatcacgcac ttcctggctg attttcatcg aacagaattt cggcccacac
    16321 atggagcaaa aatgggcgac tttacctgac tcttgcggca gggtttcatc gtgataagcg
    16381 cgggcggtaa acgggtcgag ggccagatta aactggtctt cccagcgaaa ttcgaagcgg
    16441 gctttcgaca tggcgttatc gcgaatttgc gcgcccggat gccctttcgc caggtcagcg
    16501 gcgtgggcgg caatcttata ggtgataagc ccctgcttaa catcttcttt attaggcaga
    16561 cccagatgct cttttggcgt tacgtaacag agcatcgcgc agccaaacca gccaatcatc
    16621 gccgcaccaa tccccgacgt gaagtggtca tagcccggcg caatatcggt agttagcggc
    16681 cccagagtgt aaaacggcgc ttcgtggcag tgctctaact cctcggtcat attgcggcgg
    16741 atcatctgca tcggcacgtg acctgggcct tcaatcatca cctgcacgtc atattcccag
    16801 gcaattttgg tcagttcgcc cagcgtatgc agctcggcaa actgcgcttc atcgttggcg
    16861 tcctgaatag aaccggggcg cagaccgtcg cccagcgaca gcgaaacgtc ataagcggca
    16921 cagatttcac aaatttcgcg gaagtgttga tagaggaaat tttcctgatg atgggagagg
    16981 caccatttcg ccataatcga accgccgcga gagacgatac cggtcaggcg tttcgcggtc
    17041 atcggcacat agcgcagcag tacgcccgca tggatagtga agtaatccac accttgctcg
    17101 gcctgttcca gcagcgtgtc gcggaacgct tcccaggtaa gatcttcggc gatcccgtta
    17161 accttctcca gcgcctggta gatcggcact gtaccgatcg gcaccgggct gttacgcaaa
    17221 atccactcgc gggtttcgtg aatatagcga ccggtggaga gatccatcac cgtatccgct
    17281 ccccagcgcg tggaccatac cagcttttcc acttcttctt cgatggaaga ggtgaccgcc
    17341 gagttgccga tattggcgtt aacttttacc aggaaattgc gaccaataat catcggctcc
    17401 gattccggat gattaatgtt ggccgggata atcgcacgtc cggcagcaac ttcatcacgg
    17461 acaaattccg cagtgatatt ttccggcaga tgtgcgccaa agctcattcc cggatgctgg
    17521 tggcgtaaaa cctcgctacg gatgcgctcg cggcccatat tctcgcggat ggcgatgaat
    17581 tccatttccg gcgtgatgat gccctggcgg gcgtagtgca gttgggtgac acggcgtcct
    17641 gctttggcgc gttttggtgt tagtacaccg ctaaaacgca gttcgtcgag gccatcatct
    17701 gccagccgcg ctttagtgta atcggaactg cgcacggtaa gttcttcggt atcgccgcgc
    17761 gcatcgatcc acggctggcg tagttttgcc agcccttgct gcacgttaat ggcaatctgc
    17821 ggatcaccat acgggccgga ggtgtcgtag accggaatcg cttcgttttc ttcgtactgc
    17881 ggctgttctt tgctaccgcc aattagcgtc gggctaagct ggatctcacg catcggcacg
    17941 cgcacgccgg ggtgtgtgcc agtgatataa atgcgttttg agttgggaaa ggcggtgcct
    18001 tccagggtgt cgataaaatg ttgggcccgg gcgcgttgtt cgcggcgggt cagttttgtt
    18061 gcagacatag ctcattccaa aaagttaagg acgtggcttg tcagacgacg gatgaagcaa
    18121 gagacgatcg ccgcaggggc gatgcgatag cagattaact cttgttccct tcgcaggtat
    18181 tagcctgatc aggttccgcg gatcccgaat aaacggtctc agccagttaa ggcactccga
    18241 caagaaatta gccccgcaaa tggggcattg aatgtaaatt acgcgttaac agcgcagaac
    18301 tcaagcagga tgtttgacgc gggcggcgtc aagcaccagc agaatcagct tatcttccag
    18361 cacaaagcgc gcttccagcg cctcgccgat gtcagataaa acctgttgaa actcaaggta
    18421 attatcatga tcgatggcgg tttccagact ggaatcgtag taatccataa tctgttgagt
    18481 attggcttcg agttgcggcc aaatcttcgc ggcgcgcgcg agttgcccgt tgccttccag
    18541 cttatgaaga atgcgctcat aaatactgaa atgtccggca gacaagtaat cgaccaggct
    18601 ctgacaaaaa tcatcaaggg ctttttcgtt tagcctcatg tacgattctt tgccaggctt
    18661 aatgccaacc agattgtagt aagccacgag cagatgctta cgtacatgta gccagcgatc
    18721 aaccagtttg ttacttcctc tgacgcgctc cgtcaggtta tcgagctggt taagcatgat
    18781 tgactccgca agtttgtatt caaaaactgc tcagtgagaa atgtaaaaac catgttaaac
    18841 atgccagtga tgcaaaggta gtgcaagagc tatggatcgt ataattgaaa aattagatca
    18901 cggctggtgg gtcgtcagcc atgaacaaaa attatggttg ccgaagggag aattgccata
    18961 tggcgaagcg gcaaatttcg atcttgtggg tcagcgcgca ctacaaatcg gcgaatggca
    19021 gggggaacct gtttggttag tacaacagca gcggcgtcac gatatggggt cggtacgtca
    19081 ggtcattgat ctcgatgttg ggctgtttca actggccgga cgaggcgtac aactggcgga
    19141 gttttaccga tcgcataaat actgtggtta ctgcgggcat gaaatgtatc cgagcaaaac
    19201 cgaatgggcg atgctgtgca gccattgccg tgagcgttac tacccgcaaa tcgccccctg
    19261 cattattgtt gccatccgtc gcgatgattc gatcctcctc gcccagcata cccgccatcg
    19321 taacggtgtc catacagtac ttgccggatt cgtcgaagtg ggcgaaaccc tcgagcaggc
    19381 agtcgcgcgg gaagtgatgg aagagagcgg aattaaagtt aaaaacttgc gttacgtgac
    19441 ttctcagccg tggccgtttc ctcagtcttt aatgaccgcg tttatggcgg aatatgacag
    19501 cggcgacatc gtgatcgacc cgaaagaatt gctcgaggcg aactggtatc gctatgacga
    19561 tttgccgtta ctcccgccgc ccggcaccgt agcgcgccgt ctgatagaag atacggtggc
    19621 gatgtgtcgg gcagagtatg agtgatgata cactgaccgc ctgacgcact aaggaacagc
    19681 caaaatgacc gaacttaaaa acgatcgtta tctgcgggcg ctgctgcgcc agcccgttga
    19741 tgtcactcca gtatggatga tgcgccaggc gggtcgctat ctaccggaat ataaagccac
    19801 gcgcgcccag gcgggcgatt ttatgtcgct gtgcaaaaac gccgagctgg cgtgcgaagt
    19861 gactttgcaa ccgctgcgtc gctacccgct ggatgcggcg atcctctttt ccgatatcct
    19921 caccgtgccg gacgcgatgg ggttagggct ctattttgaa gccggagaag gtccgcgttt
    19981 tacctcgcca gtcacctgca aagccgacgt cgataaactg ccaattccgg acccggaaga
    20041 tgagctgggt tacgtgatga acgcggtgcg taccattcgt cgcgaactga aaggcgaagt
    20101 gccgctgatt ggtttttccg gcagcccgtg gacgctggca acctacatgg tggaaggcgg
    20161 cagcagcaaa gccttcaccg tgatcaaaaa aatgatgtat gccgatccgc aggcgctgca
    20221 cgctctactc gataaactgg cgaaaagcgt cactttgtat ctgaatgcgc agattaaagc
    20281 cggtgctcag gctgtgatga ttttcgacac ctggggcggc gtgcttaccg ggcgcgatta
    20341 tcaacagttc tcgctttatt acatgcataa aattgttgat ggtttactgc gtgaaaacga
    20401 cggtcgccgc gtaccggtca cgctgtttac caaaggcggc ggacagtggc tggaagccat
    20461 ggcagaaacc ggttgcgatg cgctgggcct cgactggaca acggacatcg ccgatgcgcg
    20521 ccgccgtgtg ggcaataaag tcgcgttgca gggtaatatg gatccgtcga tgctgtacgc
    20581 gccgcctgcc cgcattgaag aagaagtagc gactatactt gcaggtttcg gtcacggcga
    20641 aggtcatgtc tttaaccttg gtcacggcat tcatcaggat gtgccgccag aacatgctgg
    20701 cgtgttcgtg gaggcagtgc atcgactgtc tgaacagtat caccgctaag gagtgattat
    20761 ggatctcgcg tcattacgcg ctcaacaaat cgaactggct tcttctgtga tccgcgagga
    20821 tcgactcgat aaagatccac cggatctgat cgccggagcc gatgtcgggt ttgagcaggg
    20881 cggagaagtg acgcgagcgg cgatggtgct gctgaaatat ccctcgcttg agctggtgga
    20941 gtataaagtt gcccgcatcg ccaccaccat gccttacatt ctaggttttc tttccttccg
    21001 cgaatatcct gcgctgctgg cagcgtggga gatgctgtcg caaaagccgg atttagtgtt
    21061 tgtcgatggt catgggatct cgcatcctcg ccgtcttggc gtcgccagcc attttggctt
    21121 attggtggat gtgccgacca ttggcgtggc gaaaaaacgg ctctgcggta aattcgaacc
    21181 gctctccagc gaaccgggcg cgctggcccc actgatggat aaaggcgagc agctggcctg
    21241 ggtctggcgc agcaaagcgc gctgtaaccc gttgtttatc gctaccggcc atcgggtcag
    21301 cgtggacagc gcgctggcgt gggtacaacg ctgcatgaaa ggctatcgtc tgccggagcc
    21361 aacgcgctgg gcggacgcgg tggcctcgga acgtccggcg ttcgtgcgct atacagcaaa
    21421 tcagccctaa ttcaggtaaa ctgcgggtaa tttccgtatt tgagaactca acatgttaca
    21481 aaacccaatt catttgcgtc tggagcgcct ggaaagctgg cagcacgtca ctttcatggc
    21541 ttgcttatgc gaacgcatgt accccaatta cgccatgttt tgccagcaaa ccggttttgg
    21601 tgatgggcaa atttaccgtc gtattctcga tctcatctgg gaaacgctga ccgttaaaga
    21661 cgcaaaagta aatttcgaca gccaactgga gaaatttgaa gaagcgattc cttcagccga
    21721 cgatttcgat ctgtacggcg tttatccggc aatcgatgcc tgcgtggcgt taagtgaact
    21781 ggtccattcg cgtttgagtg gtgaaacgct cgaacacgcg gtggaagtga gtaagacctc
    21841 catcacgacc gttgcgatgc tggaaatgac tcaggctggt cgtgaaatga gcgatgaaga
    21901 gcttaaagaa aacccagctg tagagcaaga atgggacatt cagtgggaaa tattccgact
    21961 tttagctgag tgcgaagaac gcgatatcga gctgataaaa ggccttaggg cagacctgcg
    22021 tgaggcgggt gagagcaata ttggtataat ttttcagcaa taagaccaga aaacgtgatt
    22081 taacgcctga tttgtcgtac ctggagtctt ccctttcgcc ccccgtctgg tctacatttg
    22141 gggggcgaaa aaaagtggct atcggtgcgt gtatgcagga gagtgctatt ctggcatttc
    22201 cgtcgcactc gatgcttagc aagcgataaa cacattgtaa ggataactta tgaacaagac
    22261 tcaactgatt gatgtaattg cagagaaagc agaactgtcc aaaacccagg ctaaagctgc
    22321 tctggagtcc actctggctg caattactga gtctctgaaa gaaggcgatg ctgtacaact
    22381 ggttggtttc ggtaccttca aagtgaacca ccgcgctgag cgtactggcc gcaacccgca
    22441 gaccggtaaa gaaatcaaaa ttgccgcagc taacgtaccg gcatttgttt ctggcaaggc
    22501 actgaaagac gcagttaagt aagattgcgt ggcagtgaac agttttaacg aaggggtggt
    22561 ttcacccctt ttgtctttct ggcgtcgatc attgatgctg gcaggcgctc tgtttctcac
    22621 tgcctgtagt cacaactctt cacttcctcc ctttaccgcc agtggatttg ctgaagacca
    22681 gggcgcggta cgcatctggc gaaaagacag cggcgataat gtgcatctgc ttgccgtgtt
    22741 tagcccgtgg cgcagtggcg ataccacgac gcgagagtat cgctggcagg gcgataacct
    22801 cacgctcatc aatatcaatg tttacagcaa accgccggtg aacattcgcg cgcgttttga
    22861 cgatcgcggc gatctgagct ttatgcaacg tgaatccgat ggggaaaagc agcagctttc
    22921 taacgaccaa atcgatttat accgttatcg tgctgatcag atccgccaga ttagcgatgc
    22981 cttacgtcag gggagagtcg tgctgcgcca ggggcgctgg catgcgatgg aacagaccgt
    23041 gaccacctgc gaagggcaaa ccattaaacc tgatttagat tcgcaggcga tagcgcatat
    23101 cgagcgccgc cagagccgct cttctgttga tgtcagcgtg gcatggctgg aagcgcccga
    23161 aggttcgcaa ttactgttag tggcaaactc tgatttctgt cgctggcaac ccaacgagaa
    23221 aacgttctga tttaccagtg gcccataccc atatgaccgc caccaccgca gccgccgtaa
    23281 cccatgccca ttccggtacc gcgcggaata cccgcttcag ccatcgcaat atctcgtttc
    23341 acccgtaact catctaacga ctgacgcaaa ttctccatct ctttggcgac cgcgttaatt
    23401 ttgctgctat ccggtgggtt cgcggctaac agggcattgt attcataacg cttcgtcacc
    23461 agttgctgtt gcagtgcgct gctttgagcg taaaagtcat tatggatttt ctgccacgct
    23521 gtctgttgtt cgctggtcaa aggcgcggca ttttgctgcc acataccgtg tccgccgtga
    23581 gcaaatgcag atgtcgatcc catcgccatt gctgaaagcg ccatcattac cagggcaatt
    23641 ttcgtgttcc gtttcatggt taatcctcca gtggttgtct tacttcgggt attgcatctt
    23701 ccgtgccaac gatgaaacgc tgatatgacg ggtaatctgg catgataaac gagtaaaaat
    23761 gactcgcctg ctgcgggtag cgagtcattt ttactcattg aaacttaagc ctttgtgtta
    23821 cagcgcaggg taagcgctga taaaagatgg catgatttct gctgtcagaa agggatgagc
    23881 aggcaaagaa gaagatgcgt tttatgcaac gttctaaaga ctccttagct aaatggttaa
    23941 gcgcgatcct ccccgtggtc attgttgggc tggtagggtt gtttgcggtg acggtgattc
    24001 gcgattatgg gcgcgagact gccgccgcca gacaaacgct gctggaaaaa ggcagtgtac
    24061 ttattcgcgc tcttgaatcc ggctcgcgcg tcggcatggg gatgcgcatg catcatgcgc
    24121 agcagcaggc cttactggaa gaaatggccg ggcagcctgg agtacgttgg tttgcggtca
    24181 cggatgaaca aggaacaatc gtgatgcata gcaactccgg catggtggga aaacagcttt
    24241 attccccgca ggaaatgcag cagttacatc ctggagatga agaagcgtgg cggcggatcg
    24301 atagcgcaga cggcgagcct gttctggaaa tttatcgcca gtttcaaccg atgtttgctg
    24361 ctggaatgca ccggatgcgc catatgcagc agtatgccgc aacaccacaa gcaattttca
    24421 tcgctttcga cgccagtaat attgtgagtg ccgaagatcg tgagcagaga aacaccctga
    24481 ttatcctctt cgccctggcg acggtcttgc tggcaagcgt attgtcattc ttctggtatc
    24541 gccgctatct gcgctcgcgc cagcttctac aagatgaaat gaagcgcaaa gagaagctgg
    24601 tggcgctggg gcatcttgcg gcaggcgttg cccacgaaat ccgtaaccca ctttcctcga
    24661 ttaaaggact ggcgaaatac tttgccgaac gcgcgccagc agggggagaa gcgcatcaat
    24721 tggcgcaggt gatggcgaaa gaagccgacc gtttaaaccg cgtggtaagc gagttgctgg
    24781 aactggttaa gccaacgcat ctggctttgc aggcggtgga tctcaacacg ctgattaacc
    24841 actcattaca gctggtaagc caggatgcaa acagccggga gatccagtta cgctttaccg
    24901 ccaacgacac attaccggaa attcaggccg atccggacag gctgactcag gtcctgttga
    24961 atctctatct taatgctatt caggcgattg gtcagcatgg cgtgattagc gtgacggtca
    25021 gcgaaagcgg cgcgggcgtg aaaatcagcg ttaccgacag cggtaaggga attgcggcag
    25081 atcagcttga agccatcttc actccgtact tcaccaccaa agccgaaggc accggattgg
    25141 ggctggcggt cgtgcataat attgttgaac aacacggtgg tacaattcag gtcgcaagcc
    25201 aggagggaaa aggctcaacg ttcaccctct ggcttccggt caatattacg cgtaaggacc
    25261 cacaaggatg acgcacgata atatcgatat tctggtggtg gatgatgaca ttagccactg
    25321 cactattttg caggctttac tgcgcggctg gggctataac gtcgcgctgg cgaacagcgg
    25381 gcgacaggcg ctggagcagg tgcgggaaca ggtttttgat cttgtgcttt gcgatgtgcg
    25441 aatggcggag atggacggca tcgccacgct gaaagagatc aaagcgttaa acccggcaat
    25501 tccggtgctg attatgactg cgtactccag cgtcgagacg gcggtagagg cactgaaaac
    25561 tggggcgctg gattatctca tcaagccgct ggatttcgat aacctacagg cgacgctgga
    25621 aaaggcgctc gcgcatacgc acagtattga tgctgaaaca cctgcggtga ctgccagcca
    25681 gttcggtatg gtcggtaaaa gctcggcgat gcaacacctg ctcagtgaaa tcgccctcgt
    25741 cgcgccatcg gaagccacgg tactgatcca cggcgattcc ggcaccggta aagagctggt
    25801 cgccagggcg attcacgcca gtagcgcacg tagcgaaaaa ccgctggtaa cgctcaactg
    25861 tgcggcactc aacgaatcct tgctggaatc tgaattgttc ggtcacgaaa aaggggcgtt
    25921 tactggagcc gataaacgcc gggaagggcg ctttgttgag gcggacggcg gcacgctgtt
    25981 tctcgatgaa attggcgata tctcgccgat gatgcaggtg cgtctgctgc gtgcgattca
    26041 ggagcgcgaa gttcagcgtg tcggtagcaa ccagactatc tcggttgatg tccggctgat
    26101 tgcggcgacc catcgcgatc ttgccgcaga ggtgaatgcc gggcgttttc gccaggatct
    26161 ctactatcgc ctgaatgtgg tggcgattga agtaccatcg ctgcggcaac ggcgggaaga
    26221 tatccctctg ctggctggcc attttctgca gcgctttgcc gagcgtaatc gcaaggcggt
    26281 aaaaggtttt acgccccagg cgatggatct gttgattcat tacgactggc cgggaaatat
    26341 tcgtgagctg gaaaacgcgg tggaacgggc agtggtgctg ctgaccgggg aatatatttc
    26401 cgaacgcgag ctgccgctgg cgattgccag tacgccgatc ccgctggggc aaagtcagga
    26461 tattcagccg ctggtggaag tggaaaaaga ggtgattctg gcggcactgg agaaaacggg
    26521 cggcaacaaa actgaagccg cccgtcagtt agggatcacg cgtaaaacgt tattggcaaa
    26581 actgtcgcgt tagttctgct cgcgttcgat agcacgccag ccgatatctt tccggcagaa
    26641 gcagtcgtcc cagtggatat cggtcattaa ggcataggcg cgtttctgcg cttctgccac
    26701 ggtatgaccc agcgcggtga cgcacagtac gcgtccgccg ttggttacca cctgctcgtc
    26761 atccgccagt tttgtgcccg cgtggaacac tttgccgtca gccacttctt ccagcggcag
    26821 gccgtggatc acatcgccgg tgcggtaatc gcccggatat ccacccgcag ccatcaccac
    26881 gccgagagaa gcgcgttcat cccactcgga cgttttctcg tccagcttgc cttcacaggc
    26941 cgccaggcag agctcaacca gatcggactt catgcgcagc ataatcggct gggtttccgg
    27001 atcgccaaag cggcagttaa attcaataac cttcggattg ccctgtttgt cgatcatcag
    27061 gcccgcatag agaaaaccgg tgtaggtgtt gccttccgcc gccatgcctt tcacggttgg
    27121 ccagataata cgttccatgg tgcgctgatg aacgtcatcg gttactaccg gcgcggggga
    27181 gtaagcgccc atcccgccgg tgtttggtcc ggtatcttta tcgcctacgc gtttgtgatc
    27241 ctggctggta gccatcggca gcacatgctc gccgtccacc atcacgataa agctcgcttc
    27301 ttcgccatcg aggaactctt cgataacgat gcgatgaccc gcgtcgccaa aagcgttgcc
    27361 cgccagcata tcgtgaacag ccgcttccgc ttcttccagc gtcatcgcca cgataacgcc
    27421 tttcccggca gccagaccgt ccgctttaat gacgattggc gcgcctttct cacgcagata
    27481 cgccagcgca ggttctacct cggtgaagtt ctggtattcc gccgtaggga tcttatggcg
    27541 ggccaggaaa tctttggtaa acgcttttga gccttccagt tgggccgcac ctgcggttgg
    27601 gccgaagatt ttcagcccgg cggcgcggaa ggtatcgacc acgcctttca ccagcggcgc
    27661 ttccgggccg acgatggtca gatcaatctt ttcgttttgt gcgaaatcca acagcgccgg
    27721 gatatcggtc acgccaatag caacgttttg cagcgcgggt tccagcgcag tgcctgcatt
    27781 acccggagca acaaaaacag tctcaaccag cggcgactgg gccgctttcc aggccagcgc
    27841 gtgctcgcgc ccgccgttac caatcactaa tactttcatc tattgctcca ttaatggcgg
    27901 aagtggcgca tgtcggtgaa gagcatcgca ataccgtgct cgtcggcggc ggcaatcact
    27961 tcgtcatcac ggatggaacc gccaggctgg attacgcagg tcacgcccgc agcggcggcg
    28021 gcatcaatac cgtcgcggaa cgggaagaac gcgtcagaag ccatcgagga acctttcact
    28081 tccaggcctt catcagcagc tttaataccg gcgattttcg cggagtacac gcggctcatc
    28141 tggcccgcgc caataccgat ggtcatattg tttttggcat agacgatagc attggatttc
    28201 acgaacttcg ccactttcca gcagaacagc gcatcgcgca gttcctgttc ggtcggctga
    28261 cgttgggtga cgacgcgcag ttcttccgca ccgaccatcc ccaggtcacg atcctgaacc
    28321 agcagaccgc cgttcacgcg tttgaaatca agacccggaa cacgctcgcc ccactgaccg
    28381 caggtcagaa cgcgtacgtt ctgcttggcg gcggtgattt tcagggcttc ttcgctggcg
    28441 gaaggcgcaa taatcacttc gacaaactga cgagaaatga tggcctgtgc ggtttccgca
    28501 tccagctcgc ggttaaaggc aatgatgccg ccgaatgcgg aggttgggtc ggttttgtac
    28561 gcgcgatcgt aagcatcaag aatggaattg ccgatagcta caccgcaagg gttggcgtgc
    28621 ttcacaatca cacatgccgg ctcggcgaac tctttcacgc actccagcgc cgcatcggta
    28681 tcggcgatgt tgttataaga gagggcttta ccctgaacct gggttgcggt agcaacggag
    28741 gcttctttca cattctcttc tatatagaag gcagcctgct ggtggctgtt ctcgccgtaa
    28801 cgcatatcct gcttcttaat gaagttcagg ttcagcgtgc gtgggaagcg accagcggct
    28861 tctttgcttt caccgtggta cgccggaacc atgctgccga agtagttggc aatcatgctg
    28921 tcgtaggcgg cagtgtgttc gaaggctttg atggcgaggt cgaaacgggt tgcaagcgtc
    28981 agcgatcctt cgttgtcatc catctcttta ataatggcgt cgtagtcgct gctcttcacc
    29041 acgattgcga catctttatg gttcttagcg gcggagcgca ccatggtcgg gccgccgata
    29101 tcgatgttct caaccgcatc ttccagcgag caaccttcac gggccacggt ctgggcgaac
    29161 ggatacaggt taacaaccac catatcgata ggctggatct gatgttcttc cataatggca
    29221 tcgtcctggc cgcgacggcc cagaatgcca ccatgtactt tcggatgcag ggtcttcacg
    29281 cgtccatcca tcatctccgg gaaaccggtg taatcggaaa cttcggttac cggcagacct
    29341 ttttctgcta acagacgggc agtgccccct gtagacagca gctccacacc gcgtgcggaa
    29401 agtgcctggg cgaattcgac gataccggct ttgtcagaaa cactgagcag agcgcggcgg
    29461 actggacgac gttgttgcat ggtaaatccc ctggatttga ctattacaga gagcgttagc
    29521 tgaatttttc gcgaaaaact cagctaacgc ccctaacggg gcatccttat ttttcgcccg
    29581 cattgtaacg aaaacgtttg cgcaacgctc gcgaattttt ctctttcaat ggtgatcaca
    29641 attttgacag tggttaccgt gggaaaaata cagaaattac attgatgatt gtggataact
    29701 ctgtgcgtaa aaaggtataa agcggggttt tgctggggaa tgcagcagtc agtcattttt
    29761 ctgcaatttt tctattgcgg cctgcggaga actccctata atgcgcctcc atcgacacgg
    29821 cggatgtgaa tcacttcaca caaacagccg gttcggttga agagaaaaat cctgaaattc
    29881 agggttgact ctgaaagagg aaagcgtaat atacgccacc tcgcgacagt gcgctaaagc
    29941 gcgtcgc
//
LOCUS       DAZUDJ010000063        28305 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.063, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000063 DAZUDJ010000000
VERSION     DAZUDJ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28305
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.063"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            203..886
                     /locus_tag="ACHY1N_003629"
     CDS             203..886
                     /locus_tag="ACHY1N_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HFS4045857.1"
                     /translation="MNLKKIFFSAVTVSVLCALTGCDYIEEGKPESSLLKQQEEHNNK
                     IVLLEKQQAQLKSQLETIQKQQTGIINSTKTLTHVIKSVKDQQNTFIFTEFNPAKTKY
                     FILNNGSVALAGRVLSIDATENGSVIHISLVNLLSTPISNIGFNATWGGEKPVDAKEF
                     ARWQQLLFNTSMKSTLKLLPGQWQDINLTLKGVSPNNLGYLKLAINMENIQFDNLPSA
                     ENRQKRSKK"
     gene            930..5781
                     /gene="ehaG"
                     /locus_tag="ACHY1N_003630"
                     /pseudo
     CDS             930..5781
                     /gene="ehaG"
                     /locus_tag="ACHY1N_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric autotransporter adhesin EhaG"
     gene            6149..7804
                     /gene="lldP"
                     /locus_tag="ACHY1N_003631"
     CDS             6149..7804
                     /gene="lldP"
                     /locus_tag="ACHY1N_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015727 - lactate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HFS4045858.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWR
                     GIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFR
                     FGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEW
                     VINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPS
                     DAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLG
                     WLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCIVGVITTLQAYVLTWMIP"
     gene            7804..8580
                     /gene="lldR"
                     /locus_tag="ACHY1N_003632"
     CDS             7804..8580
                     /gene="lldR"
                     /locus_tag="ACHY1N_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HFS4045859.1"
                     /translation="MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVS
                     RNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSEQNIVQPLKTLMADDPDYSFDIL
                     EARYAIEASTAWHAAMRATPGDKEKIQLCFEATLSEDPDIASQADVRFHLAIAEASHN
                     IVLLQTMRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFSGDADGARKAM
                     MAHLSFVHTTMKRFDEDQARHARITRLPGEHNEHSREKNA"
     gene            8577..9767
                     /gene="lldD"
                     /locus_tag="ACHY1N_003633"
     CDS             8577..9767
                     /gene="lldD"
                     /locus_tag="ACHY1N_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent L-lactate dehydrogenase"
                     /protein_id="HFS4045860.1"
                     /translation="MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSE
                     VALRQRILKNMSDLSLETTLFNEKLSMPVALGPVGLCGMYARRGEVQAAKAADAHGIP
                     FTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLY
                     ALATAGQAGVANLLNLIEKEMKVAMTLTGAKSINEITQDSLVQGLGKELPTALAPMAK
                     GNAA"
     gene            9953..10426
                     /gene="trmL"
                     /locus_tag="ACHY1N_003634"
     CDS             9953..10426
                     /gene="trmL"
                     /locus_tag="ACHY1N_003634"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFS4045861.1"
                     /translation="MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRL
                     RRAGLDYHEFTAVTRHHDFRAFLEAENPQRLFALTTKGTPAHSAVNYQDGDYLMFGPE
                     TRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGALLRD"
     gene            complement(10479..11300)
                     /gene="cysE"
                     /locus_tag="ACHY1N_003635"
     CDS             complement(10479..11300)
                     /gene="cysE"
                     /locus_tag="ACHY1N_003635"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HFS4045862.1"
                     /translation="MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI"
     gene            complement(11380..12399)
                     /gene="gpsA"
                     /locus_tag="ACHY1N_003636"
     CDS             complement(11380..12399)
                     /gene="gpsA"
                     /locus_tag="ACHY1N_003636"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFS4045863.1"
                     /translation="MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATL
                     ERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     QTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSA
                     QEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKD
                     ERSSH"
     gene            complement(12399..12866)
                     /gene="secB"
                     /locus_tag="ACHY1N_003637"
     CDS             complement(12399..12866)
                     /gene="secB"
                     /locus_tag="ACHY1N_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015369180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HFS4045864.1"
                     /translation="MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDL
                     DTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYC
                     PNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(12929..13180)
                     /gene="grxC"
                     /locus_tag="ACHY1N_003638"
     CDS             complement(12929..13180)
                     /gene="grxC"
                     /locus_tag="ACHY1N_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HFS4045865.1"
                     /translation="MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK"
     gene            complement(13322..13753)
                     /locus_tag="ACHY1N_003639"
     CDS             complement(13322..13753)
                     /locus_tag="ACHY1N_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFS4045866.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDG
                     SGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK"
     gene            13998..15542
                     /gene="gpmM"
                     /locus_tag="ACHY1N_003640"
                     /gene_synonym="pgmI"
     CDS             13998..15542
                     /gene="gpmM"
                     /locus_tag="ACHY1N_003640"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HFS4045867.1"
                     /translation="MSVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKDRAFFANPVLTGA
                     VDKAKNAGKAVHIMGLLSVGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQPDAAMEDGDALIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKY
                     DTIICNYPNGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQ
                     MRDPATGQAHTAHTNLPVPLIYVGDKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            15576..16835
                     /gene="envC"
                     /locus_tag="ACHY1N_003641"
     CDS             15576..16835
                     /gene="envC"
                     /locus_tag="ACHY1N_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418070.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HFS4045868.1"
                     /translation="MTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADERDQLKSIQ
                     ADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNKQIDEMNAS
                     IAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQ
                     ETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALNERKKTLAGLESS
                     IQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEATRKGTTYK
                     PTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWKGMVIGASEGTEVK
                     AIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQPIALVGSS
                     GGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            16839..17798
                     /locus_tag="ACHY1N_003642"
     CDS             16839..17798
                     /locus_tag="ACHY1N_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HFS4045869.1"
                     /translation="MFPFRRNVLAFATLLALSSPVLAGKLAIVIDDFGYRPHNENQVL
                     AMPSAISVAVLPDSPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKNTLRPEMSSDE
                     IERIIRSAVNNVPYAVGINNHMGSKMTSNLFGMQKVMQALERYNLYFLDSVTIGNTQA
                     MRAAQGTGVKVIKRKVFLDDSQNEADIRVQFNRAIDLARRNGSTIAIGHPHPSTVRVL
                     QQMVYNLPPDITLVKASSLLNEPQVDTSTPPKNAVPDAPRNPFRGVKLCKPKKPIEPV
                     YANRFFEVLSESISQSTLIVYFQHQWQGWGKQPEAAKFNASAN"
     gene            complement(17785..18819)
                     /gene="waaH"
                     /locus_tag="ACHY1N_003643"
     CDS             complement(17785..18819)
                     /gene="waaH"
                     /locus_tag="ACHY1N_003643"
                     /EC_number="2.4.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate:LPS(HepIII) glycosyltransferase"
                     /protein_id="HFS4045870.1"
                     /translation="MMNSTSKLSVIIPLYNAGDDFRTCMESLITQTWTALEIIIINDG
                     STDNSVEIAKHYAENYPHVRLLHQANAGASVARNRGIEVATGKYVAFVDADDEVYPTM
                     YETLMTMALEDDLDVAQCNADWCFRETGETWQSIPSDRLRSTGVLTGPDWLRMGLSSR
                     RWTHVVWMGVYRRDVIVKNNIKFIAGLHHQDIVWTTEFMFNALRARYTEQSLYKYYLH
                     NTSVSRLHRQGNKNLNYQRHYIKITRLLEKLNRNYADKITIYPEFHQQITYEALRVCH
                     AVRKEPDILTRQRMIAEIFTSGMYKRLITNVRSVKVGYQALLWSFRLWQWRDKTRSHH
                     RITRSAFNLR"
     gene            complement(19058..20083)
                     /gene="tdh"
                     /locus_tag="ACHY1N_003644"
     CDS             complement(19058..20083)
                     /gene="tdh"
                     /locus_tag="ACHY1N_003644"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008743 - L-threonine 3-dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFS4045871.1"
                     /translation="MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKE
                     NLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSG
                     KVILSWD"
     gene            complement(20093..21289)
                     /gene="kbl"
                     /locus_tag="ACHY1N_003645"
     CDS             complement(20093..21289)
                     /gene="kbl"
                     /locus_tag="ACHY1N_003645"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFS4045872.1"
                     /translation="MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPDLIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGM
                     EDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGK
                     QLGVIA"
     gene            complement(21564..22421)
                     /gene="yibB"
                     /locus_tag="ACHY1N_003646"
     CDS             complement(21564..22421)
                     /gene="yibB"
                     /locus_tag="ACHY1N_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418075.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YibB"
                     /protein_id="HFS4045873.1"
                     /translation="MKSSTTIITAYFDIGRGDWTANKGFREKLARSVDVYFSYFERLA
                     ALENEMIIFTSPDLKPRVEAIRNGKPTTVIVIDIKKKFRYIRSRIEKIQKDESFTNRL
                     EPRQLKNPEYWSPEYVLVCNLKAYFVNKAINMGLVKTPLVAWIDFGYCRKPNVTRGLK
                     IWDFPFDESKMHLFTIKKGLTVTSQQQVFDFMIGNHVYIIGGAIVGSQHKWKEFYKLV
                     LESQKITLNNNIVDDDQGIFVMCYYKRPDLFNLNYLGRGKWFDLFRCFRSNTLGAKMQ
                     ALRIFLSRK"
     gene            22725..23657
                     /gene="rfaD"
                     /locus_tag="ACHY1N_003647"
     CDS             22725..23657
                     /gene="rfaD"
                     /locus_tag="ACHY1N_003647"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008712 - ADP-glyceromanno-heptose
                     6-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HFS4045874.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     DVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFT
                     QADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA"
     gene            23667..24713
                     /gene="rfaF"
                     /locus_tag="ACHY1N_003648"
     CDS             23667..24713
                     /gene="rfaF"
                     /locus_tag="ACHY1N_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HFS4045875.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLQARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRKLGHSLREKRYDRAYVLPNSFKSALVPFFAGI
                     PHRTGWRGEMRYGLLNDVRVLDKEAWPLMVERYIALAYDKGIMRTAQDLPQPLLWPQL
                     QVSEGEKSYTCNQFSLSSERPMIGFCPGAEFGPAKRWPHYHYAELAKQLIDEGYQVVL
                     FGSAKDHEAGNEILAALNTEQQAWCRNLAGETQLDQAVILIAACKAIVTNDSGLMHVA
                     AALNRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDAAEGYHQSLIDITPQR
                     VLEELNALLLQEEA"
     gene            24717..25709
                     /gene="rfaC"
                     /locus_tag="ACHY1N_003649"
     CDS             24717..25709
                     /gene="rfaC"
                     /locus_tag="ACHY1N_003649"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008920 - lipopolysaccharide
                     heptosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HFS4045876.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQI
                     PSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAAL
                     VTRLAHGVKHGLDWQTAREPLASLFYNCKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
                     GDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWG
                     APHEEERAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TVYGPTDPGLIGGYGKNQVECRSTSMSLADLPAQTVFQNLNLEIITNKLTSEIR"
     gene            25706..26914
                     /gene="rfaL"
                     /locus_tag="ACHY1N_003650"
     CDS             25706..26914
                     /gene="rfaL"
                     /locus_tag="ACHY1N_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase RfaL"
                     /protein_id="HFS4045877.1"
                     /translation="MTSTLFFSLEKKNWIAYWNRALVFLFITTYFLGGITRYKHLIVI
                     LMTITTIVYLCKRPKHYLSLFKTFLFGSVAILTIAALLSLLQSPDAGASMKEIFKAII
                     ENTLLCTIAIPIILRDEKREDVEKIVFFSFISALGLRCFSELITYYKDYQQGIMPFAD
                     YRHRSISDSMVFLFPALLNLWLIKSAKYRISFVVLSVIFIFLILGTLSRGAWLSVLVI
                     GLIWILMFKQWKLLLVGVMVAIIALSVIFTHKEMTAKLTYKLQQTNSSYRYANGTQGS
                     ALDLILENPVIGYGYGNVAYKDVYNKRVIDYPEWTFRQSIGPHNFALFIWFGTGLLGL
                     VSLMMLYCAILKECIKNGVKNKYRSPYNAYYIILLSFIGYFVIRGNVEQIEPNLLGVY
                     AGLLLAMKNK"
     gene            complement(26950..28092)
                     /locus_tag="ACHY1N_003651"
     CDS             complement(26950..28092)
                     /locus_tag="ACHY1N_003651"
                     /EC_number="2.4.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylglucosaminyltransferase"
                     /protein_id="HFS4045878.1"
                     /translation="MVDKIIFTVTPIFSIPPRGAAAVETWMYQVAQRTNFPNRIVCIK
                     NPGYSNYTFVNDNCSIHRVGFSRIYKRLFQKWTRLDPLPYSQRILNIAHDFPITKESV
                     IVVHNSMKLYTQIRKRAPQARVVIHMHNAFEPKLLEQNVKMIVPSLYLEKYYQSYLAN
                     ADIEIVPNGIDLETYQSNFQPITRSELNISPEEKIIFYAGRIVPDKGILLLMQSFEKL
                     AAAHKNLKLVVIGDYTEMSKSDKGAYQRNVREIAKRLKDRCIMLGSIPPEKMHCYYPL
                     ADLVVIPSQFQEPFCMVAIEAMGAGKPVLVSTRGGMTEFVKENTTGFHLKEPMTADSI
                     SSDILKTLANPELTAVAKQGQDFVFEHYSWDGVTQRFEEVIHNWFE"
     gene            complement(28101..>28305)
                     /locus_tag="ACHY1N_003652"
     CDS             complement(28101..>28305)
                     /locus_tag="ACHY1N_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008918 - lipopolysaccharide
                     3-alpha-galactosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 8 C-terminal
                     domain-containing protein"
                     /protein_id="HFS4045879.1"
                     /translation="TKPWHDWANYASADYFRNIYNISPWRNIPYKKAVKKHEYKEKYK
                     HLLYQKKFLDGVFTAIKYNVMKG"
BASE COUNT         7372 a         7042 c         6961 g         6930 t
ORIGIN      
        1 attagaatcc acgaaaaata atatattcat acaaacacag acatcttttg aaacgaatga
       61 tacattttta tgatgaatgc ttaaaacaat atttaatcga cacacatcac tgtcattaat
      121 gtaaagcaac atagctcacc aataatacaa tggacaactc taccggcatt gatcgctggt
      181 cggaggaaat aaggattttt acatgaactt gaagaagatt tttttcagtg ctgtcactgt
      241 ttcagttctc tgcgcattaa cgggatgtga ctacattgaa gaaggcaagc cagaaagtag
      301 tttactgaaa caacaagaag aacataataa taaaattgtg ctacttgaaa aacaacaagc
      361 acagctaaag agtcaactcg aaactattca aaaacaacaa actggcataa taaacagtac
      421 aaagacttta actcacgtaa ttaaatccgt taaagaccaa caaaatactt ttatttttac
      481 cgagtttaac ccagcaaaaa cgaagtattt catcctgaac aacggttcgg tggctttagc
      541 gggtcgagtg ttatccattg acgccacaga gaatggtagt gttattcata tctcactggt
      601 caacttatta agtacaccta tctcaaacat tggttttaat gcgacatggg gtggtgaaaa
      661 acctgtcgat gccaaagagt ttgcccggtg gcaacaatta cttttcaaca catcaatgaa
      721 atccacattg aaattattac caggtcaatg gcaagacatt aatttgaccc tgaagggtgt
      781 atcgcccaat aacctgggat atctgaagtt agccatcaac atggaaaata ttcagttcga
      841 caatcttccc tctgctgaaa atcggcagaa aagaagcaaa aaataaatgc agttagtacg
      901 cttataacaa ggaatagcga gcatcattaa tgaacaaaat atttaaagtt atctggaacc
      961 ctgcgacagg gaattatact gttaccagcg aaacggcaaa aagccgtggc aagaaatctg
     1021 ggcgcagtaa gctgttaatt tctgcgctgg ttgcgggtgg aatgttgtcg tcgtttgggg
     1081 cattggcgaa tgccgggaat gacaacggtc agggtgttga ttacggtagt ggatcagctg
     1141 gctgacggct gggttgctat aggcaaaggg gcgaaagcaa atacttttat gaacaccagt
     1201 ggttccagta ctgctgtggg ttatgacgct atagctgaag gccaatatag ctctgccatc
     1261 gggtcaaaaa cccatgcgat tggcggtgca tcaatggcct ttggggttag tgcaatatca
     1321 gaaggcgata gaagtatagc actgggtgcc tcttcgtatt cattgggcca atactcaatg
     1381 gccctcggcc gttattcaaa agcattgggt aaattgtcta ttgctatggg ggactcttcc
     1441 aaagcggaag gagcaaacgc cattgccctg ggaaatgcca ctaaagctac tgagattatg
     1501 agtattgctc ttggcgacac cgccaatgcg tcaaaagcgt attcaatggc gctgggagca
     1561 agtagcgtcg catctgaaga aaacgcaatt gccctggggc gtagcagtgt agctagcggt
     1621 actgacagcc tcgcatttgg cagacaatca cttgccagcg cagcgaacgc tattgcgata
     1681 ggtgctgaga ccgaagccgc tgaaaatgca actgctattg gcaataatgc gaaggcaaaa
     1741 gggactaata gcatggcaat ggggttcgga agccttgccg ataaagtcaa tactatcgca
     1801 ttaggaaatg gcagccaggc tctggcagat aatgcaatcg ccataggcca gggcaacaaa
     1861 gctgatggcg tggatgccat cgctctgggt aatggtagcc agtcgagagg cttaaacacc
     1921 attgccttag gcacagccag taatgcaact ggtgataaga gtcttgcgct tggtagtaat
     1981 agcagtgcca acggtattaa ctctgtcgcg ctgggcgcag attccattgc ggatttagac
     2041 aataccgtct ctgtcggcaa tagttcatta aaacgcaaga tcgttaatgt gaaaaatggc
     2101 gcgatcaagt ctgacagtta cgatgccatt aatggttcac agctttatgc cattagcgac
     2161 tcggtagcaa aaaggcttgg aggaggggct gcagtagatg ttgatgacgg tactgttaca
     2221 gcaccaacct acaatttaaa aaatggtagc aaaaataacg taggggctgc gctcgctgta
     2281 cttgatgaaa acaccctgca atgggaccaa accaaaggca aatacagcgc tgctcatggt
     2341 actagtagcc caactgccag cgtaatcacc gatgttgcgg atggcacgat ttcagcctcc
     2401 agtaaggatg cggttaacgg ttcccaactg aaagctacca atgacgatgt cgaagccaac
     2461 accgccaata tcgctactaa taccagcaac attgccacga atacggcaaa tattgccacc
     2521 aataccacca atatcaccaa cctgacggat tccgttggtg accttcaggc tgatgccctg
     2581 ctctggaacg aaactaaaaa ggcattcagt gcagctcacg gccaggatac caccagcaaa
     2641 atcaccaacg ttaaagatgc cgacctgacg gctgacagca ctgatgctgt taacggctct
     2701 cagctgaaaa ccaccaacga tgctgtggcg acgaatacca ccaatatcgc caataacact
     2761 tccaatattg ccactaacac caccaacatc tctaacctga ctgagacggt gactaatctt
     2821 ggtgaggatg cgctgaaatg ggataaggac aatggtgtat tcacggcagc tcatggcacc
     2881 gagaccacca gcaaaatcac caacgttaaa gatggcgacc tgacgactgg cagcaccgat
     2941 gccgttaacg gctctcagct gaaaaccacc aacgatgccg tggcgacgaa taccaccaat
     3001 atcgccacta acaccaccaa catctctaat ctgactgaga cggtgactaa tcttggtgag
     3061 gatgcgctga aatgggataa ggacaatggt gtcttcactg cagctcatgg caacaatacc
     3121 gccagcaaaa tcaccaatat cctggacggc acagtcactg caaccagttc cgatgccatt
     3181 aacggtagcc agctttatga cttaagcagc aatatcgcca cctacttcgg cggcaatgct
     3241 tctgtgaata ctgacggtgt gtttaccggt ccaacctaca aaatcggtga aacaaattat
     3301 tataacgtcg gcgatgcact ggctgcgatt aactcctcat ttagcacgtc tctcggcgat
     3361 gctctgcttt gggatgccac cgcaggtaaa ttcagtgcca aacacggtac taatggtgac
     3421 gcaagcgtga tcactgatgt cgcagatggt gaaatttcag actccagttc tgacgcagta
     3481 aacggctcac aactccacgg cgtgagcagt tatgttgttg atgcgctggg gggtggtgcc
     3541 gaagtcaatg cagacggcac catcactgcg ccgacgtaca ccattgctaa tgctgattac
     3601 gataatgtcg gtgatgccct gaatgctatc gataccactc ttgacgacgc tctgctctgg
     3661 gatgcggacg ccggtgaaaa tggtgcattt agcgccgctc acggaaaaga taaaactgcc
     3721 agtgtaatca ctaacgtcgc taacggtgca atctctgctg ccagcagcga cgcgattaac
     3781 ggctcacaac tctataccac caataagtac atcgctgatg cgctgggtgg tgacgcagaa
     3841 gtcaacgctg acggcaccat caccgcaccg acttacacca ttgcgaacgc cgagtacaac
     3901 aacgtcggtg acgccctgga tgcgcttgat gataacgccc tgctgtggga tgagactgcc
     3961 aatggcggtg ctggagccta caatgccagc catgacggta aagccagcat catcactaat
     4021 gtcgctaatg gcagtattag tgaggacagt accgatgcag tgaacggttc tcagttgaat
     4081 gcgacgaata tgatgattga gcagaacacc caaattatca atcagctcgc tggtaacacc
     4141 gacgcaacct atatccaaga aaacggtgcg ggtattaact atgtgcgtac taacgacgac
     4201 ggcttagcgt tcaacgacgc cagcgcacag ggtgttggcg ctacagctat aggttataac
     4261 tctgtcgcca aaggcgatag cagcgtagct attggtcagg gcagctacag cgacgttgat
     4321 acgggtatcg ccctgggtag cagctctgtt tccagccgag tgattgccaa aggctcccgt
     4381 gacaccagca taacggaaaa tggcgttgtt attggttacg acaccacgga tggcgaactg
     4441 ctcggtgcat tgtctatcgg tgatgacggt aaatatcgtc aaatcatcaa cgtagccgat
     4501 ggttccgaag cccatgacgc cgttacggtt cgtcaattgc agaatgcgat tggtgcggtc
     4561 gcaaccacgc cgactaaata cttccacgct aattcaacgg aagaagattc actggcagtg
     4621 ggaactgact cgctggcaat gggtgcgaaa accatcgtga atggcgataa aggtattggt
     4681 atcggttatg gtgcctacgt ggacgcgaat gcacttaacg gcattgccat tggtagcaat
     4741 gcgcaagtca ttcatgtcaa cagtattgcg ataggtaatg gttctacgac cactcgtggc
     4801 gctcaaacca attataccgc ctacaacatg gacgcaccgc agaactctgt cggtgaattc
     4861 tcagtcggta gtgcggatgg tcaacgtcag atcactaacg tcgcagcagg ttcggctgat
     4921 accgatgcgg tcaacgtggg tcagttgaaa gtaacggatg cgcaggtttc ccagaatacc
     4981 cagagcatta ctaacctgga taatcgggta acgaatcttg attcacgcgt caccaatatc
     5041 gaaaacggta ttggcgatat cgtcaccacc ggtagcacca agtacttcaa gaccaatacc
     5101 gatggtgtag atgccagcgc gcagggtaaa gatagcgtcg cgattggttc tggctccatt
     5161 gctgccgcgg ataacagcgt cgcactgggt acagggtctg tggcaaccga agaaaatacg
     5221 atctctgtag gctcatctac taatcaacgt cgtatcacca acgtagccgc aggtaaaaac
     5281 gacaccgatg ctgttaacgt ggcacagttg aagtcttccg aagctggcgg tgtgcgttac
     5341 gacaccaaag ctgatggttc tatcgactat agcaatatca ccctcggtgg cggcaacggc
     5401 ggtacgactc gtatcagcaa cgtctccgct ggcgtcaaca acaacgacgc ggtgaattac
     5461 gcgcagttga agcaaagcgt gcaggaaacg aagcaataca ccgatcagcg aatggttgag
     5521 atggataaca aactgtctaa aactgaaagc aagttgagcg gtggtatcgc ttctgcaatg
     5581 gcaatgaccg gtctgccgca ggcttataca ccgggtgcca gcatggcttc tattggtggc
     5641 ggtacttaca acggtgaatc ggcagttgct ttaggtgtat cgatggtgag cgccaatggt
     5701 cgttgggtct acaaattaca aggtagtacc aatagccagg gtgaatactc cgccgcactc
     5761 ggtgccggta ttcagtggta atgatccatt aagttagtgt gactaagggc aaacgccaaa
     5821 ttgcctgatg cgttacgcgc atcaggcaag ataaggcgct ccgggtcaac aatctaaggg
     5881 caattctctg atgaggattg cccttttctt taccagacat ctccccccac aagaattggc
     5941 cctaccaatt cttcgcttat ctgacctctg gttcacaatt ccccaattaa aactcacatc
     6001 aatattgcca atacataaca tttagttaac cattcattgt cattatccct acacaacaca
     6061 attggcagtg ccacttttac acaacgtgtg acaaggagat gagcaacaga ctcattacac
     6121 gatgtgcgtg gactccagga gacctgcaat gaatctctgg caacaaaact acgatcccgc
     6181 cgggaatatc tggctttcca gtctgatagc atcgcttccc atcctgtttt tcttctttgc
     6241 gctgattaag ctcaaactga aaggatacgt cgccgcctca tggacggtag caatcgccct
     6301 tgccgtggct ttgctgttct ataaaatgcc ggtcgctaac gcgctggcct cggtggttta
     6361 tggcttcttc tatggtttgt ggcccatcgc gtggatcatt attgcagcag tgttcgtcta
     6421 taagatctcg gtgaaaaccg ggcagtttga catcattcgc tcgtctattc tttcgataac
     6481 ccctgaccag cgtctgcaaa tgctgatcgt cggtttctgt ttcggcgctt tccttgaagg
     6541 agccgcaggc tttggcgcac cggtagcaat taccgccgca ttgctggtcg gcctgggttt
     6601 taaaccgctg tacgccgccg gactgtgcct gattgttaac accgcgccag tggcatttgg
     6661 cgcgatgggc attccaatcc tggttgccgg acaagtaaca ggcatcgaca gctttgagat
     6721 tggccagatg gtggggcggc agctaccgtt tatgaccatt atcgtgctgt tctggatcat
     6781 ggcgattatg gacggctggc gcggtatcaa ggagacgtgg cctgcggtcg tggttgcggg
     6841 cggctcgttt gccatcgctc agtaccttag ctctaacttc attgggccgg agctgccgga
     6901 cattatctct tcgctggtat cactgctctg cctgacgctg ttcctcaaac gctggcagcc
     6961 agtgcgcgta ttccgttttg gtgatttggg ggcgtcacag gttgatatga cgctggccca
     7021 caccggttac actgcgggtc aggtgttacg tgcctggaca ccgttcctgt tcctgacagc
     7081 taccgtaaca ctgtggagta tcccgccgtt taaagccctg ttcgcatcgg gtggtgcgct
     7141 gtatgagtgg gtgatcaaca ttccggtgcc gtacctcgat aaactggttg cccgtatgcc
     7201 accagtggtc agcgaggcta cagcctatgc cgccgtgttt aagtttgact ggttctctgc
     7261 caccggcacc gccattctgt ttgctgcact gctctcgatt gtctggctga agatgaaacc
     7321 gtctgacgct atcagcacct tcggcagcac gctgaaagaa ctggctctgc ccatatactc
     7381 catcggtatg gtgctggcat tcgcctttat ttcgaactat tccggactgt catcaacact
     7441 ggcgctggca ctggcgcaca ccggtcatgc attcaccttc ttctcgccgt tcctcggctg
     7501 gctgggggta ttcctgaccg ggtcggatac ctcatctaac gccctgttcg ccgcgctgca
     7561 agccaccgca gcacaacaaa ttggcgtctc tgatctgttg ctggttgccg ccaataccac
     7621 cggtggcgtc accggtaaga tgatctcccc gcaatctatc gctatcgcct gtgcggcggt
     7681 aggcctggtg ggcaaagagt ctgatttgtt ccgctttact gtcaaacaca gcctgatctt
     7741 cacctgtata gtgggcgtga tcaccacgct tcaggcttat gtcttaacgt ggatgattcc
     7801 ttaatgattg ttttacccag acgcctgtca gacgaggttg ccgatcgtgt gcgggcgctg
     7861 attgatgaaa aaaacctgga agcgggcatg aagttgcccg ctgagcgcca actggcgatg
     7921 caactcggcg tatcacgtaa ttcactgcgc gaggcgctgg caaaactggt gagtgaaggc
     7981 gtgctgctca gtcgacgcgg cggcgggacg tttattcgct ggcgtcatga cacatggtcg
     8041 gagcaaaaca tcgtccagcc gctaaaaaca ctgatggccg atgatccgga ttacagtttc
     8101 gatattctgg aagcccgcta cgccattgaa gccagcaccg catggcatgc ggcaatgcgc
     8161 gccacacctg gcgacaaaga aaagattcag ctttgctttg aagcaacgct aagtgaagac
     8221 ccggatatcg cctcacaagc ggacgttcgt tttcatctgg cgattgccga agcctcacat
     8281 aacatcgtgc tgctgcaaac catgcgcggt ttcttcgatg tcctgcaatc ctcagtgaag
     8341 catagccgtc agcggatgta tctggtgcca ccggtttttt cacaactgac cgaacaacat
     8401 caggctgtca ttgacgccat tttttccggt gatgctgacg gggcgcgtaa agcaatgatg
     8461 gcgcacctta gttttgttca caccaccatg aaacgattcg atgaagatca ggctcgccac
     8521 gcacggatta cccgcctgcc cggtgagcat aatgagcatt cgagggagaa aaacgcatga
     8581 ttatttccgc agccagcgat tatcgcgccg cagcgcaacg cattctgccg ccgttcctgt
     8641 tccactatat ggatggtggt gcatattctg aatacacgct gcgccgcaac gtggaagatt
     8701 tgtcagaagt ggcgctgcgc cagcgtattc tgaaaaacat gtccgactta agcctggaaa
     8761 cgacgctgtt taatgagaaa ttgtcgatgc cggtggcgct aggtccggta ggtttgtgtg
     8821 gcatgtatgc gcgacgcggc gaagttcagg cagccaaagc ggcggatgcg catggcattc
     8881 cgtttactct ctcgacggtt tccgtttgcc cgattgaaga agtcgcgcca gccatcaagc
     8941 gcccaatgtg gttccagctt tatgtactgc gcgatcgcgg ctttatgcgt aacgcgctgg
     9001 agcgagcaaa agcagcgggt tgttcgacgc tggttttcac cgtggatatg ccgacaccgg
     9061 gagcgcgtta tcgtgatgcg cattctggaa tgagcggccc gaacgcggca atgcgccgct
     9121 atttgcaggc ggtgacgcat ccgcaatggg cgtgggatgt gggcctgaac ggtcgtccgc
     9181 atgatttagg taatatctca gcttatctcg gcaaaccgac cggactggaa gattacatcg
     9241 gctggctggg aaataacttc gatccgtcca tctcatggaa agaccttgag tggatccgcg
     9301 atttctggga tggcccgatg gtgatcaaag ggatcctcga tccggaagat gcgcgcgatg
     9361 cagtacgttt tggtgctgat gggattgtgg tttctaacca cggtggccgc cagctggacg
     9421 gtgtactctc ttccgctcgt gcactgcctg ctattgcaga tgcggtgaaa ggtgatatcg
     9481 ccattctggc ggatagcgga attcgtaacg ggcttgatgt cgtgcgtatg attgcgctcg
     9541 gtgccgacac cgtactgctg ggtcgtgctt tcttgtatgc gctggcaaca gcgggccagg
     9601 cgggtgtagc taacctgcta aatctgatcg aaaaagagat gaaagtggcg atgacgctga
     9661 ctggcgcgaa atcgatcaat gaaattacgc aggattcgct ggtgcagggg ctgggtaaag
     9721 agttgcctac ggcactggct ccgatggcga aagggaatgc ggcatagtcg tttgagcccc
     9781 ctcaccctaa ccctctccct cagggagtgg ggaccgttcg gcgctgtatg tactccctca
     9841 ctctgaaacg acaccgcact ctttttttct ccctcgcccc tccggggtga ggggaaaagg
     9901 ccgcactgct caccaatttt ctgctatcct gcccccgcac taagggggca gtatgctaaa
     9961 catcgtactt tacgaaccag aaattccgcc aaatactggc aatatcatcc gtctttgcgc
    10021 taataccggc tttcgtctgc atatcatcga accgatggga tttgcctggg acgataagcg
    10081 cctgcgccgc gcggggctgg actatcacga gtttaccgcc gttacgcgtc atcatgactt
    10141 tcgcgcgttc ctcgaagcag aaaatcccca gcgcctgttt gccctcacca cgaaaggtac
    10201 gcctgctcac agcgccgtaa actatcagga tggcgattat ctgatgttcg gcccggaaac
    10261 acgcggcctg ccagcgagca ttcttgatgc cctgcccgct gaacaaaaaa ttcgcattcc
    10321 gatggtgccg gacagccgca gcatgaacct gtccaatgcg gtgtcagttg tggtgtatga
    10381 agcctggagg cagctgggat atccgggagc gttgttgaga gattagttac tgtatgccgg
    10441 atagatgatt acatcgcatc cggcacgatc acaggacatc agatcccatc cccatactca
    10501 aatgtatggt taataccgtt gaaatgctgg tccatatcca ttgatggctt atcgctgtct
    10561 ggtttaccga caatacgagc cggaacgcca gcggcggttg tatgcggcgg caccggttgc
    10621 agcaccacgg aacctgcgcc aatcttcgcg ccgcgaccaa cttcaatatt gccgaggatt
    10681 ttcgcgcccg cgccaatcat cacaccttca cgaattttcg ggtgacggtc accaccagat
    10741 ttacccgtac cgccaagcgt cacagattgc agaatcgata cgtcgttttc aattaccgcc
    10801 gtttcaccca caacgatgcc cgtggcgtgg tcgagcataa tgccacggcc aatttttgct
    10861 gccgggtgaa tatcgacctg gaacgtcaca gaaacctggt tttgcagaaa gattgccaat
    10921 gcgcgacgcc cctgattcca caaccagtga ccgatgcgat aggcctgcaa ggcatgaaaa
    10981 cccttcaggt ataacaacgg ggttgagtat ttatcgactg ccgggtcgcg ggtacgcacc
    11041 gcctgaatat cacaggccgc agaggcgatc atttccgggt cagcggcgta ggcttcttcc
    11101 accacttcac ggatagcaat agcaggcata attggcgatg acagcttgtt cgccagcatg
    11161 tagctcagtg cactaccaag gttttcgtgc ttgagtagcg tcgcgtggta aaaactggcc
    11221 agcattggct cacagtccgc cagcgttctg gcttcggctt taatattgtt ccagacaatt
    11281 tccagttctt cacacgacat tgcttactcc acacgatgag ataatgaccg gcccgttctg
    11341 cgcgggccgg gtcatagcgg taacaaaggt tccctggggt tagtggctgc tgcgctcgtc
    11401 cttgcgtgca cgacctaata acgtcaatgc tgcctcgcgc gcgttttttc cgcaatataa
    11461 tacttgataa atttcctcgg ttattggcat ttcaacgccg aagcgatgcg ccagttcgcg
    11521 gacttctttc gtattgcggt agccttccac cacctgacca atcttctcct gcgcgctttg
    11581 tacatccatg ccctgaccga gcatcatgcc aaaacggcgg ttacgcgact ggttgtcggt
    11641 acaggtaagc accagatcgc caagccccgc catgcccata aaggtggcag gatcggcacc
    11701 cagcgccgca ccaagacgcg acatttcagc cagcccacgg gtgatcagcg ccgtacgcgc
    11761 attcgcacca aaaccgatac cgtcggacat ccccgcgcca atggcaatga cgtttttcac
    11821 cgcaccgcca agctgcacac cgatgaaatc cgggttgctg taaacgcgga aacttttgcc
    11881 acagtgcagc aattgttgga gatcatcggc aaaggtctgg tcggtagagg ccaacgaaat
    11941 agccgtcggt aaacctgccg ccagttcttt cgcaaacgtt gggccagaga taaccgccag
    12001 cggaatttga tcgcctaagg cctcacgcgc cacgtcctgt aacagacgtc cggtttccgc
    12061 ttccagccct ttggtcgccc acaccagacg cgcatcagga cgcatcagcg gtttaatctg
    12121 gcgcagcact tcaccaaaga catggctggg tacgacgacg agaatattac ggctggctgc
    12181 cagcgcagtg gcgagatcgc tttcaagatg gagcgtatcg ggaaaaggca catcggggag
    12241 aaacgcggcg ttacagcggt cgcgttcaag cgttgcgata tgttcagggt catggcccca
    12301 gaggacaacc tcgtggccat ttcttgccag ggtaatggca agagcggtgc cgtacgagcc
    12361 ggcaccgatc acagtcattg aagcattacg ttggttcatc aggcatcctg atgttcttca
    12421 gtaccttcgc cagcctgctg ctgcaaatag ttcatgaaca gcgcatcgaa gttaaccggc
    12481 gcaaggttca gttgcgggaa tgtaccgcgg gataccatgc tggtgatgca ctcacgagca
    12541 tacgggaaca gaatgttcgg gcagtatgcg cccaggcaat gtgccatctg ggtgccttcg
    12601 atacccgcga tggagaaaat accgccctgc tgaacttcac acaggaacgc ggtttcttcg
    12661 cccagggagg ccgttacggt aacacgcagt accacttcgt atacgtcatc tgccagttgg
    12721 gaagatgccg tatccagatc aagtttaact tctggttgcc aatctttctg gaaaacgtgc
    12781 ggcgcgttcg gcgcttcgaa agagatatcc ttggtataaa tacgttggat ctggaaagtc
    12841 atttcagtgt tgttttgttc tgacatgtgt agaaaaccct taagtgttgt ccttaaatac
    12901 tgcgcaatgt aatgccaacg ttcacacgtt atttcagcag gggatccagt ccaccacgtg
    12961 catccaatgc atacaagtca tcacagccgc caatgtgctg tgcgtcaata aaaatctggg
    13021 gaaccgtggt gcgaccgctg cgtttgatca tctcttcacg cttggcggca ttgccatcga
    13081 tcggcagctc ctggaaactc acgcccttgc tgctcagcag tgcttttgca cgatggcaat
    13141 acgggcaggt ttctttggta tagatttcaa cattggccat aaattagctc ctgttttttt
    13201 accctgaaat ttcatgttgc agggcggcag caaaatggag tgtccccaga agcttataac
    13261 aataagtcgc tgggggccta attgcagcta acggcctgca tcatgaaaga cgacaggtaa
    13321 attatttgcc gcgcaccaga ggcaagtttt cgccagccca gccagcaacg ccctctttca
    13381 gcacgaatac ttgcgcaaaa ccagctttcg tcagcgcgtt tgcaggctcc tggcactgca
    13441 tgccagaacc gtctaccacg ataaccggtt tgtctttgtg cttctcaagc tcaccaacat
    13501 tgttggcttt gatttcactc ggcaacagat tgatagaacc tgcgatatgg cctttacgga
    13561 agtcatcacg ctgacgtaaa tccacaacca cagcgtcttc tttgttgatc agacgcgtag
    13621 cttcaccacg agtaatcacc ttcactttcg aggtcaggct cttaaacgta gtcacaagaa
    13681 ccgccaccag taacgcgatc caggcgatac tcagtatggg atgacggcca acaaattgca
    13741 taatttcttg catggggggt aacaactccc gacgtagtga ttaaaaaaac caggaaagga
    13801 gtatacctgc gcggtgcggc aaatacagcc agcgcgttaa ctggaatgca attttgcggg
    13861 gcacgacgaa aaaaaagcgc aaatctggca tcggcttgcc gcgagcggtc gtatattttg
    13921 atcttcagag gctattttat cgattcagct gtagtaaaat tacgcaaatt ttgactcttg
    13981 agtatgaggt tgtcgcaatg tcggtttcta aaaaacctat ggtactggtg attctggatg
    14041 gctatggcta tcgtgaagaa cagcaggata acgccatttt tagtgctaaa accccggtaa
    14101 tggatgcact gtgggccaat cgtccgcata ccctgatcga cgcttccggt ctggaagtcg
    14161 gtctgcctga ccgtcagatg ggtaactccg aagtaggcca cgttaacctg ggtgccggcc
    14221 gcatcgtgta tcaggacctg actcgtctgg acgttgaaat caaagatcgc gctttctttg
    14281 ctaatccagt gctgactggc gcggtagata aagcgaaaaa cgcaggtaaa gcagtacaca
    14341 ttatgggtct gctctccgta ggcggcgtac acagccacga agatcacatc atggcgatgg
    14401 tagaactggc agctgaacgc ggcgcagaaa aaatctacct gcacgcattc cttgacggtc
    14461 gcgacacccc gccgcgcagt gctgaatcct cgctgaaaaa atttgaagag aaatttgctg
    14521 cgctgggtaa aggccgcgta gcgtccatca ttggtcgtta ctacgcgatg gaccgcgata
    14581 accgttggga tcgcgttgaa aaagcctatg acctgctgac tctggcgcag ggtgagttcc
    14641 aggccgatac tgccgttgct ggtttgcagg cagcttatgc tcgcgacgaa aacgacgagt
    14701 tcgtgaaagc gaccgttatt cgtgcagaag gtcagccaga tgcggcaatg gaagacggcg
    14761 atgcgctgat tttcatgaac ttccgtgctg accgcgcgcg tgaaatcact cgtgcattcg
    14821 tgaacgctga tttcgatggc ttcgcgcgta agaaagtggt taacgtcgat ttcgtgatgc
    14881 tgaccgaata cgccgctgac atcaaaactg cggttgctta cccacccgct tccctggtta
    14941 acaccttcgg cgagtggatg gcgaaaaacg acaaaactca gttgcgtatt tccgaaaccg
    15001 aaaaatatgc ccacgttact ttcttcttca acggtggcgt agaagagtcg ttcaaaggcg
    15061 aagatcgcat tctgatcaac tcaccgaaag tggctaccta cgatctgcaa ccggaaatga
    15121 gctccgcaga gctgaccgaa aaactggttg cggccatcaa gagcggcaaa tacgacacca
    15181 ttatctgtaa ctatccgaac ggcgacatgg taggtcacac cggggtgatg gaagcggcag
    15241 ttaaagcggt tgaagcactg gatcactgcg tggaagaagt cgcgaaagcg gttgagtccg
    15301 tgggtggaca actgctgatc accgctgacc acggtaacgc tgaacagatg cgcgatccgg
    15361 caacgggtca ggcacacacg gcacacacca acctgccagt tccgctgatt tatgttggtg
    15421 ataagaacgt gaaagcggtt gaaggcggca aactttctga catcgcgccg accatgttgt
    15481 cgctgatggg tatggaaatc ccgcaagaga tgactggtaa gccgctgttc atcgtggaat
    15541 aatccctccc catgagggga aaggcgatta ataccatgac acgggccgtg aaaccgcgca
    15601 ggtttgcaat caggcccatc atctacgcca gcgttcttag cgctggcgta ttgttgtgcg
    15661 ccttttccgc ccacgcggat gagcgtgacc aactcaaatc tattcaggcc gatatcgccg
    15721 caaaagagcg cgcggtacgc caaaagcaac aacaacgcgc aagcctgctc gcacaattga
    15781 aaaagcagga agaagcgatc tctgaagcca cccgtaagct gcgcgaaacg caaaacacgc
    15841 tcaatcaact caataaacag attgatgaga tgaacgcgtc gattgccaaa ctggagcagc
    15901 aaaaagccgc ccaggagcgc agcctcgccg cgcaactgga tgccgcattc cgtcagggcg
    15961 agcataccgg tattcagcta attctcagcg gtgaagaaag ccagcgtgga cagcgtttac
    16021 aggcttattt cggctatctc aaccaggcgc gacaagaaac cattgcccag ttgaagcaaa
    16081 cgcgtgaaga agtcgccatg cagcgtgctg aactggaaga gaaacaaagc gagcaacaaa
    16141 cgctgttata tgaacagcgc gcccaacagg cgaaactgac tcaggcgctg aacgagcgta
    16201 aaaagacgct ggcagggctg gagtcttcca tccagcaagg tcagcaacag ttgagcgagc
    16261 tgcgcgccaa cgaatcccgt ctgcgtaaca gcattgcccg tgcggaagcc gcggcgaaag
    16321 cgcgtgcaga acgagaagca cgtgaggccc aggcggttcg cgaccgccag aaagaagcga
    16381 cgcgtaaagg caccacctac aaaccgactg aaagcgaaaa atcgctgatg tcccgtaccg
    16441 gtggtctggg cgcgccgcgt ggtcaggcat tctggccggt tcgcgggccg acgctgcatc
    16501 gctatggcga acagctacag ggtgaattac gctggaaagg gatggtgatt ggtgcctctg
    16561 aaggtactga agttaaagcg attgccgacg gtcgggtgat tctggctgac tggctgcaag
    16621 gctacggtct ggtggtggtg gttgagcatg gtaaaggcga catgagtctt tacggctata
    16681 atcagagcgc actggtgagc gttggttcgc aggttcgcgc gggccagcca attgcactgg
    16741 tgggcagcag tggcggtcag ggtcggcctt cactctattt cgaaattcgc cgccagggtc
    16801 aggcggtcaa tccacagccg tggttgggaa gataagtttt gtttccattt cgtcgtaacg
    16861 ttcttgcatt tgccactctg ttggcgctct cctcccccgt acttgctggc aaacttgcca
    16921 tcgtcattga tgattttggg tatcgcccgc acaacgaaaa ccaggtgctg gcgatgcctt
    16981 ccgctatctc cgtcgctgta ttacccgatt caccgcacgc cagagagatg gcgaccaaag
    17041 cgcataacag cggtcacgaa gtgttgattc atctgccaat ggcaccgttg agtaaacagc
    17101 cgctggagaa aaatacgctg cgcccggaga tgagcagcga cgaaattgag cgcattattc
    17161 gtagtgcggt caataacgtg ccctatgccg tggggatcaa caaccacatg ggtagcaaga
    17221 tgacctctaa cctgtttggt atgcagaaag tgatgcaggc gctggagcgt tacaatcttt
    17281 acttcctcga cagtgtaacc attggtaata cccaggcgat gcgcgccgcg caaggcactg
    17341 gcgtgaaggt tattaaacgg aaggtgttcc tcgacgattc acagaacgaa gcggacatcc
    17401 gtgtgcagtt caatcgcgca attgatctgg cgcgtcgcaa cggttcaacc attgccattg
    17461 ggcatcctca cccttcaacg gtacgcgtgc tacaacagat ggtttataac ctgccgccag
    17521 acattacgct ggtgaaagcc agcagcttgc tgaatgaacc gcaggttgat acgtctacac
    17581 cgccgaaaaa cgctgtgcct gatgcaccgc gtaatccgtt ccgtggcgtg aagctgtgca
    17641 aaccgaagaa accgatagaa cctgtttatg ctaatcgctt ctttgaagta ttaagcgaaa
    17701 gcatcagcca gagcacgctg atcgtttact tccagcatca gtggcaaggc tggggcaaac
    17761 agcccgaagc ggcgaagttt aacgctagcg caaattaaag gcgctacgcg taatgcgatg
    17821 gtgcgaccgc gttttgtcgc gccattgcca taagcggaaa gaccacagta acgcctggta
    17881 acccaccttc acgctgcgca cattggtaat caggcgctta tacataccgg aagtaaatat
    17941 ctcggcaatc atccgttggc gggtaagaat atccggctct ttgcgcaccg catggcaaac
    18001 acgcaatgct tcgtaagtta tttgctgatg aaattccgga taaatcgtaa ttttgtcggc
    18061 ataatttcga tttaatttct ccagcaggcg ggtaatctta atatagtgac gttgataatt
    18121 aaggttttta ttcccttgtc tatgcaaccg actcactgac gtattatgca gataatattt
    18181 atataatgat tgctcggtat atcgcgcacg cagcgcatta aacatgaatt ctgttgtcca
    18241 gacaatatcc tgatgatgta atccggcaat aaatttaatg ttatttttaa caataacatc
    18301 gcggcgataa acccccatcc agacaacgtg agtccaacgg cgcgaagaaa gccccatccg
    18361 cagccagtcc gggccggtta atacaccggt tgagcgaagg cgatcgctgg ggatggattg
    18421 ccaggtttct cccgtttcac gaaaacacca gtcagcgttg cactgcgcca cgtcgaggtc
    18481 gtcctctaac gccatggtca tcagcgtttc gtacatggtg ggatagacct catcgtcagc
    18541 atcgacaaaa gcgacatatt tgcccgtcgc cacctcgatc ccacgattac gcgctaccga
    18601 tgcgccagca ttcgcctgat gcaacaaacg aacgtgcgga tagttttctg cgtaatgctt
    18661 tgctatttca acagaattat ccgttgaacc atcgttaata ataatgattt ccagagcagt
    18721 ccaggtttgc gtaattaaag attccataca agtgcggaaa tcatcgcccg cattatataa
    18781 cggaataata acactaagtt tactggtgct gttcatcata aattaccgac gacctctgaa
    18841 gttatcctga cgttttacag gctttgtatt aagaaactat taagcctgtg agatattatt
    18901 tttacaggtg agagagtcac ttcagggtag agagataatg agaacagcta tataagagat
    18961 cagcgcaatt acgaactctt tattacactg acaggatttt acatatttaa cggattatcc
    19021 tcaggcaaaa gggctggaat accagccctt gttcgtgtta atcccagctc agaattactt
    19081 tcccggactg gcccgaacgc atagcgtcaa agcccttctg gaaatcatca atagagaaac
    19141 gatgggtaat gatcggcgag agatcgaggc cagactgaat cagcgccgcc atcttgtacc
    19201 aggtttcaaa catctcacga ccgtaaatac ctttaatgaa caagccttta aagatcactt
    19261 tggtccagtc gatagacata tcagacggcg gaatacccag catcgcaata cggccgccgt
    19321 ggttcatggt gtcaagcatg gtacgaaacg ctggcggcgc accggacatt tccagaccga
    19381 catcaaagcc ttcggtcatg cccagttctg ccatcacatc attaaggttt tctttcgcga
    19441 cgttaaccgc acgggtgata cccattttgc gcgccagctc aaggcggtat tcgttaacat
    19501 cggtgatcac cacattgcgt gcaccaacgt gtttcgccac cgccgcagcc ataataccta
    19561 tcggacctgc accagaaacc agcacatctt cgcccaccag atcgaacgac agcgcggtat
    19621 gcacggcgtt accgaaggga tcaaaaatgg aagccaggtc gtcggagata ttgtctggga
    19681 ttttgaaggc gttgaacgcc gggatcacca gatattcggc gaagcagccc ggacggttaa
    19741 cgccgacgcc gatcgtgttg cggcacagat gggtacgacc gccacgacag ttgcgacagt
    19801 gaccgcaggt gatatggcct tcgccagaaa cgcgatcgcc gattttgaag cctttcactt
    19861 cctgaccaat acctaccact tcaccgacat attcatggcc tacgaccatc ggcaccggga
    19921 tggttttttg cgaccactca tcccagttat agatgtggac gtcagtcccg cagatggctg
    19981 ttttacggat tttaatcagc agatcgttat gcccgagttc cggtacagga acgtcggtca
    20041 tccagatgcc ctcttccgct ttcagtttgg ataacgcttt catctcacat cctcaggcga
    20101 taacgcccag ttgtttacca atacgcgtga atgcttctac tgcacgcgta atttgctcag
    20161 gggtatgcgc cgcagacatc tgggtacgaa tacgcgcctg acctttcgga acgaccggat
    20221 agaagaaacc ggtgacgtaa atgccctctt tttgcagctc acgggcaaat ttctgcgcca
    20281 ctactgcatc gccaagcatg accggaataa tggcatgatc ggctcccgcc agggtaaagc
    20341 ccgccgccga catttgctca cggaactggc gcgcgttcgc ccacagacgg tcacgcagtt
    20401 cgctgcccgc ttcgaccatc tccagtactt tgatggacgc ggcaacaatg gccggtgcca
    20461 gcgagttgga gaacaggtac ggacgagaac gctggcgcag ccactcaacc acctctttgc
    20521 gcgccgcggt ataaccacca gaagccccgc ccagcgcttt accaagcgta ccggtgataa
    20581 tatcgacccg gcccatcaca tcgcagtatt catgggaacc acgaccattt tcaccgacaa
    20641 aaccgaccgc gtgggagtcg tctaccatca ccagggcatc gtatttatct gccagatcgc
    20701 aaacgccctt cagattggca atcacgccgt ccatcgagaa tacaccatcg gtggcaatca
    20761 gcacatgacg cgcaccggct tcacgcgctt ctttcagacg agcttcaagc tcctgcatat
    20821 cgttgttggc atagcgatag cgtttagctt tacacagacg cacaccatca ataatagacg
    20881 cgtggttcag tgcgtcggag ataatggcgt cttccgcgcc cagcagcgtt tcaaacaggc
    20941 caccgttagc atcaaagcag gaagagtaga gaatcgcatc ttccatcccc aggaaggccg
    21001 ccagtttttg ttcaagctct ttatggctgt cctgagtgcc gcaaataaaa cgcaccgaag
    21061 ccatgccgaa accgtgagaa tccattcccg cctttgccgc cgcaatcaga tcaggatgat
    21121 tcgccagccc gagatagttg ttggcacaaa agttaatgac gtggcttcca tcagccacag
    21181 tgatatctgc ttgctgcgca gacgtaataa tgcgctcttc tttaaacaac ccttccgccc
    21241 gtgcggtttc cagatcgttg gttaactgct gataaaattc tccacgcatt gcgattctcc
    21301 agacagggca aattccagca catattaccc aaacttatag gtcgcgacga gatgacgcgt
    21361 taacacttct gcaaaattca ggataaataa cgtgtaactt gatgtctctc aacacctaca
    21421 gatagtagaa aaactgtaca gttttggctg ggcataatga tgattgattt tactgcattg
    21481 atataaaaag aaaaaatgat gccaaagcat catttttcct atctcagttg gtatcaaaac
    21541 gctacccact aatggaggga aacctatttt cttgaaagga aaattctcag cgcctgcatt
    21601 tttgccccta aagtgttact cctgaagcag cgaaacaaat cgaaccattt tcctctcccc
    21661 agatagttta ggttgaagag atcggggcgt ttgtaatagc acatgacaaa aatgccctgg
    21721 tcatcatcca caatgttatt atttagtgtt attttttgac tttccagaac taatttatag
    21781 aattctttcc atttatgctg tgaaccaaca attgcgcccc caataatata tacatgattg
    21841 ccaatcatga aatcaaaaac ctgttgttga gatgtgacag taagcccttt ttttatagtg
    21901 aaaagatgca tcttactttc atcaaatggg aaatcccaaa ttttcaatcc tcgagttaca
    21961 tttggcttac ggcaatagcc aaaatctatc cacgcaacaa gaggcgtttt cactaagccc
    22021 atgttgatag ctttatttac aaaataggcc ttaaggttac ataccaaaac atactctggt
    22081 gaccagtact ctgggttttt taattgtcga ggctcaagtc tatttgtaaa cgactcatct
    22141 ttttgaattt tttcgatacg acttctgata tatctaaatt tcttttttat atcgataacg
    22201 ataaccgttg ttggttttcc gttgcgaatc gcttcaaccc ttggtttcaa atcgggagaa
    22261 gtgaaaataa tcatctcatt ttcaagtgcg gccagacgct caaagtaact aaaataaaca
    22321 tcaactgaac gagctagttt ttcacggaac cctttattag cagtccaatc ccctctacca
    22381 atgtcaaaat atgcagtgat aattgtggtg gatgatttca ttactaataa gaccattaat
    22441 ataaaaaaag aattatatca taaatattaa cagaatgtat actgtatatt atccattcaa
    22501 atgcttccgt tatttatcat acatcggaat attgatacta aagcactatt cacatgcaaa
    22561 accaacatcc gccatgaagg actagctaaa acccaaacta gtttgttgca attagcatcc
    22621 ttgcacctct atgtaaaggg ctgaagggat tcggatgtga tggtatgatt acagacattc
    22681 gtgtctgaga ttgtctctga ctccataatt cgaaggttac agttatgatc atcgttaccg
    22741 gcggcgcggg ctttatcggc agcaacatcg ttaaagccct gaatgataaa ggcatcaccg
    22801 atattctggt ggtggacaac ctgaaagacg gcaccaagtt tgtgaacctg gtggatctga
    22861 atatcgcaga ctatatggat aaggaagact tcctgatcca gattatggct ggcgaagagt
    22921 tcggcgatgt cgaagcgatt ttccacgaag gcgcgtgctc ttccaccacc gagtgggacg
    22981 gcaagtatat gatggataac aactatcaat actccaagga gctgctgcac tactgcctgg
    23041 agcgtgaaat cccgttcctg tacgcttctt ccgcagccac ctacggcgga cgcacctccg
    23101 actttattga atcccgcgag tacgaaaaac cgttgaacgt ctacggttac tcaaaattcc
    23161 tgtttgatga atatgttcgc caaatcctgc cggaagcgaa ctcgcagatt gttggcttcc
    23221 gctatttcaa cgtttatgga ccgcgtgaag gccataaagg cagcatggcg agcgtcgctt
    23281 tccatctcaa cacccagctt aataacggtg aatcaccgaa gctgttcgaa ggtagcgaga
    23341 actttaaacg cgacttcgtc tatgttggcg atgtggcaga tgtaaacctg tggttcctgg
    23401 aaaatggcgt ttccggcatc ttcaatctcg gcaccggtcg tgcggaatcc ttccaggctg
    23461 tagctgatgc tacgctggct tatcacaaga aaggccagat cgaatacatt ccgttcccgg
    23521 ataagctgaa aggccgctac caggcgttca ctcaggcaga tctgacaaat ctgcgcgcgg
    23581 cgggttacga caaaccgttc aaaaccgttg ctgaaggtgt aacggaatac atggcctggc
    23641 tgaatcgcga cgcataagag ctctgcatga aaatactggt gatcggcccg tcttgggttg
    23701 gcgacatgat gatgtcgcaa agtctctatc gcacgctcca ggcgcgctat ccccaggcga
    23761 taatcgatgt gatggcaccg gcatggtgcc gtccattatt atcgcggatg ccggaagtta
    23821 acgaagctat ccctatgcct ctcggtcacg gagcgctgga aatcggcgaa cgccgcaaac
    23881 tgggtcatag cctgcgtgaa aagcgctacg accgcgccta cgtcttacct aactccttca
    23941 aatccgcatt agtgcctttc ttcgcgggta ttcctcatcg caccggctgg cgcggcgaga
    24001 tgcgctacgg tttactcaac gatgtacgcg tgctcgataa agaagcctgg ccgctaatgg
    24061 tggaacgcta tatagcgctg gcctatgaca aaggcattat gcgcacagca caagatctgc
    24121 cgcagccatt gttatggccg cagttgcagg tgagcgaagg tgaaaaatca tatacctgta
    24181 atcaattttc gctttcatca gaacgtccga tgattggttt ttgcccgggt gcggagtttg
    24241 gtccggcaaa acgctggcca cactaccact atgcggagct ggcaaagcag ctgattgatg
    24301 aaggttatca ggtggttctg tttggctcgg cgaaagatca tgaagcaggc aatgagattc
    24361 ttgccgcttt aaataccgag cagcaggcat ggtgtcggaa cctggcgggg gaaacacagc
    24421 ttgatcaagc ggttatcctg attgcagcct gtaaagccat tgtcactaac gattctggcc
    24481 tgatgcacgt tgcggcggcg ctcaatcgtc cgctggttgc cctgtatggt ccaagtagcc
    24541 cggacttcac accgccgcta tcccataaag cgcgcgtgat ccgtctgatt accggctatc
    24601 acaaagtgcg taaaggtgac gctgcggagg gttatcacca gagcttgatc gacattactc
    24661 cccagcgcgt actggaagaa ctcaacgcgc tattgttaca agaggaagcc tgacggatgc
    24721 gggttttgat cgttaaaaca tcgtcgatgg gcgatgttct ccatacgttg cccgcactca
    24781 ctgatgccca gcaggcaatc ccagggatta agtttgactg ggtggtggaa gaagggttcg
    24841 cacagattcc ttcctggcac gctgccgttg agcgagttat tcctgtggca atacgtcgct
    24901 ggcgtaaagc ctggttctcg gcccccataa aagctgaacg caaagcgttt cgtgaagcgc
    24961 tacaagcaga gaactatgac gcagttatcg acgctcaggg gctggtaaaa agcgcggcac
    25021 tggtgacacg tctggcgcat ggcgtaaagc atggattgga ctggcaaacc gctcgcgaac
    25081 ctttagccag cctgttttac aattgtaagc atcatattgc aaaacagcag cacgccgtag
    25141 aacgcacccg cgaactgttt gccaaaagtt tgggctatag caaaccgcaa acccagggcg
    25201 attatgctat cgcacagcat tttctgacga acctgcctac agatgctggc gaatatgccg
    25261 tatttcttca tgcgacgacc cgtgatgata aacactggcc ggaagaacac tggcgagaat
    25321 tgattggttt actggctgat tcaggaatac ggattaaact tccgtggggc gcgccgcatg
    25381 aggaagaacg ggcgaaacga ctggcggaag gatttgctta tgttgaagta ttgccgaaga
    25441 tgagtctgga aggcgttgcc cgcgtgctgg ccggggctaa atttgtagtg tcggtggata
    25501 cggggttaag ccatttaacg gcggcactgg atagacccaa tatcacggtt tatggaccaa
    25561 ccgatccggg attaattggt gggtatggga agaatcaagt agagtgtcgt tctacaagta
    25621 tgtctcttgc agatttgcca gctcaaaccg tttttcaaaa tttaaatctt gaaataataa
    25681 ccaataagtt gacatcggag ataagatgac ctcaacatta tttttctctc tcgagaaaaa
    25741 aaactggata gcgtactgga acagagctct cgtattctta ttcattacca cctatttttt
    25801 gggtgggatt acaaggtata aacatcttat tgttattctt atgacaataa cgacaatcgt
    25861 ctatctctgc aaacggccaa aacactatct ctcactattt aaaacatttc tttttggtag
    25921 tgttgccata ttaactattg ctgcattgct gtcacttctt caatcccctg atgcaggtgc
    25981 tagcatgaag gaaattttca aagctattat tgagaatact ttactatgca caatagcaat
    26041 accgatcata ttgagagacg agaaaagaga agatgtcgaa aaaatcgttt tcttctcatt
    26101 tattagtgcg ttgggcttac gctgtttttc tgaattgatt acctattata aggactatca
    26161 acaagggata atgccattcg cagattatag acaccgtagc atttctgact cgatggtctt
    26221 tttattccct gcattgttaa atctctggct tatcaaatca gcaaaatacc gcatttcttt
    26281 tgtggttcta agcgttattt ttatttttct gatattagga actttatcca gaggggcctg
    26341 gctttccgtg ttagtcattg gattaatatg gattctgatg tttaaacaat ggaagttact
    26401 attagtagga gtaatggttg ccatcattgc attgtcggtt attttcacac ataaggagat
    26461 gaccgcaaag ctaacgtata aacttcaaca aactaatagt tcttatcgct atgcaaatgg
    26521 tactcaaggc agcgcactcg atctaatatt agaaaatcct gttattggtt atggttacgg
    26581 taacgttgca tataaagatg tctataataa acgtgtcatt gattatccag aatggacctt
    26641 tagacaatca atagggccac ataattttgc gctattcatc tggtttggca ctggtttatt
    26701 agggctggta agtcttatga tgctatactg tgcaatattg aaagagtgta taaaaaatgg
    26761 cgtcaagaat aaatatcgct caccatataa tgcatattat ataatcttac tatcttttat
    26821 aggttatttt gttatccgtg gaaacgtaga acaaattgaa ccaaatttat taggcgttta
    26881 cgccggctta ttattagcga tgaaaaacaa gtaaaaaata aaaaaggctg cataatgcgg
    26941 cctttttatt tattcaaacc aattatgaat aacctcttcg aatctttgag ttacgccatc
    27001 ccaactgtag tgttcaaaca caaagtcctg accttgcttt gcaactgctg ttaattcagg
    27061 attcgctaac gtttttaaaa tatcgctgct tatggagtct gcagtcatag gttcttttaa
    27121 atggaatccc gtagtatttt ctttgacaaa ttccgtcatc cccccacgcg tactcactaa
    27181 aacaggctta ccagcaccca tagcttcaat tgccaccatg caaaatggtt cctggaactg
    27241 ggaaggaatg acgactaaat ctgccagtgg gtaataacaa tgcatctttt caggcggtat
    27301 gcttcctaac ataatgcaac gatccttcaa acgttttgca atttccctga cattgcgttg
    27361 atatgcacct ttgtcacttt tactcatttc tgtataatca ccaatcacaa ctaattttaa
    27421 atttttgtga gcagcggcca atttttcgaa tgattgcatc aacagcaata tgcctttgtc
    27481 agggacgata cgcccagcat aaaaaataat tttctcttca ggggagatat taagttcgct
    27541 tctagtgatc ggctgaaaat tagattgata ggtttctaaa tcaattccat ttggtacaat
    27601 ctcaatatct gcatttgcta aataagattg gtaatacttt tccaagtata aactaggcac
    27661 tatcatttta acattttgct caagcaattt tggttcaaat gcattatgca tatgtataac
    27721 cactcttgcc tgaggagctc gcttacgaat ttgagtgtat agcttcatgc tattatgaac
    27781 tacaataaca ctttctttcg ttataggaaa atcatgtgca atattcaata ttctctgtga
    27841 atatggaaga ggatcaagtc ttgtccattt ttgaaataac cgcttatata tgcgactgaa
    27901 tccaacccta tgaatactac aattatcatt aacaaaggtg taatttgagt atcctggatt
    27961 tttgatacaa acaatacgat ttggaaaatt ggtacgctga gcaacctgat acatccacgt
    28021 ttcaacagca gccgctccgc gaggaggaat tgaaaaaata ggagtaaccg taaatattat
    28081 tttatcaacc atctcgtata ttaacctttc ataacattat atttaattgc tgtaaaaaca
    28141 ccatcgagaa attttttctg gtaaagcaag tgtttatatt tttctttgta ctcatgtttt
    28201 ttaacagctt ttttataagg tatatttctc catggtgata tattataaat attacgaaaa
    28261 taatctgcag aggcgtagtt cgcccaatca tgccatggct tagtt
//
LOCUS       DAZUDJ010000064        26384 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.064, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000064 DAZUDJ010000000
VERSION     DAZUDJ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26384
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.064"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(101..691)
                     /gene="tccP2"
                     /locus_tag="ACHY1N_003653"
                     /pseudo
     CDS             complement(101..691)
                     /gene="tccP2"
                     /locus_tag="ACHY1N_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_107686092.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tir-cytoskeleton coupling protein TccP2"
     gene            complement(1016..1205)
                     /locus_tag="ACHY1N_003654"
                     /pseudo
     CDS             complement(1016..1205)
                     /locus_tag="ACHY1N_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001346438.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein EspV"
     gene            complement(1294..1381)
                     /locus_tag="ACHY1N_003655"
     tRNA            complement(1294..1381)
                     /locus_tag="ACHY1N_003655"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1345..1347),aa:Ser,seq:tga)
     gene            1808..2926
                     /gene="hyaA"
                     /locus_tag="ACHY1N_003656"
     CDS             1808..2926
                     /gene="hyaA"
                     /locus_tag="ACHY1N_003656"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
                     /protein_id="HFS4045880.1"
                     /translation="MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAW
                     ALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAE
                     EVFEDIIAQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTC
                     ASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVD
                     RMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACS
                     STRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGV
                     VAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA"
     gene            2923..4716
                     /gene="hyaB"
                     /locus_tag="ACHY1N_003657"
     CDS             2923..4716
                     /gene="hyaB"
                     /locus_tag="ACHY1N_003657"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HFS4045881.1"
                     /translation="MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSP
                     GYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVK
                     IHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMI
                     PDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNV
                     LPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQ
                     ERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLG
                     RILCRAHEAQWAAGKLQYFFNKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAP
                     RGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELISVQVR"
     gene            4735..5442
                     /gene="hyaC"
                     /locus_tag="ACHY1N_003658"
     CDS             4735..5442
                     /gene="hyaC"
                     /locus_tag="ACHY1N_003658"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HFS4045882.1"
                     /translation="MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLP
                     SVSGEATYLFYMGYIRLIHFSAGMIFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWW
                     QGVWYEIRWYLLLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIF
                     APFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMV
                     NGYRSHKFGKISNKERS"
     gene            5439..6026
                     /gene="hyaD"
                     /locus_tag="ACHY1N_003659"
     CDS             5439..6026
                     /gene="hyaD"
                     /locus_tag="ACHY1N_003659"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HFS4045883.1"
                     /translation="MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEYVEIVDG
                     GTQGLNLLGYVESASHLLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSE
                     VLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQSALAQLAAWGIVP
                     QPANESRCLNYDCLSMENYEGVRLRQYRMTQEEQG"
     gene            6023..6421
                     /gene="hyaE"
                     /locus_tag="ACHY1N_003660"
     CDS             6023..6421
                     /gene="hyaE"
                     /locus_tag="ACHY1N_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HFS4045884.1"
                     /translation="MSNDTPFDALWQRMLARGWTPVSESRLDDWLTQAPDGVVLLSSD
                     PKRTPEVSDNPVMISELLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTGGN
                     YRGVLNGIHPWAELINLMRGLVEPQQERAS"
     gene            6418..7275
                     /gene="hyaF"
                     /locus_tag="ACHY1N_003661"
     CDS             6418..7275
                     /gene="hyaF"
                     /locus_tag="ACHY1N_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HFS4045885.1"
                     /translation="MSETFFHLLGPGTQPNDDSFSMNPLPITCQVNDEPSMAALEQCA
                     HSPQVIALLNELQHQLSERQPPLGEVLAVDLLNLNADDRHFINTLLGEGEVSVRIQQV
                     DDSESEIQEAIFCGLWRVRRRRGEKLLEDKLEAGCAPLALWQAATQNLLPTDSLLPPP
                     IDGLMNGLPLAHELLAHVRNPDAQPHSINLTQLPISEADRLFLSRLCGPGNIQIRTIG
                     YGESYINATGLRHVWHLRCTDTLKGPLLESYEICPIPEVVLAAPEDLVDSAQRLSEVC
                     QWLAEAAPT"
     gene            7409..8953
                     /gene="appC"
                     /locus_tag="ACHY1N_003662"
     CDS             7409..8953
                     /gene="appC"
                     /locus_tag="ACHY1N_003662"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HFS4045886.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAIMETIYVVTG
                     KTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALM
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNLSALWILNANGWMQYPTGAHFD
                     IDTLRMEMTSFSELVFNPVSQVKFVHTVMAGYVTGAMFIMAISAWYLLRGRERDVALR
                     SFAIGSVFGTLAIIGTLQLGDSSAYEVAQVQPVKLAAMEGEWQTEPAPAPFHVVAWPE
                     QDQERNAFAIKIPALLGILATHSLDKPVPGLKNLMAETYPRLQRGRMAWLLMQEISQG
                     NREPHVLQAFRELEGDLGYGMLLSRYAPDMNHVTAAQYQAAMRGAIPQVAPVFWSFRI
                     MVGCGSLLLLVMLIALVQTLRGKIDQHRWVLKMALWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDILPTYSAHSALTTGQLAFSLIMIVGLYTLFLIAEVYLMQKYARLGPSAMQSEQ
                     PTQQQG"
     gene            8965..10101
                     /gene="appB"
                     /locus_tag="ACHY1N_003663"
     CDS             8965..10101
                     /gene="appB"
                     /locus_tag="ACHY1N_003663"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HFS4045887.1"
                     /translation="MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARNDD
                     ERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPL
                     AFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
                     FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLA
                     GYWLWVGIDGFVLLAQDANGPSNPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPL
                     LTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQL
                     TLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY"
     gene            10114..10206
                     /gene="cbdX"
                     /locus_tag="ACHY1N_003664"
     CDS             10114..10206
                     /gene="cbdX"
                     /locus_tag="ACHY1N_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HFS4045888.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLDPRLKS"
     gene            10282..11580
                     /gene="appA"
                     /locus_tag="ACHY1N_003665"
     CDS             10282..11580
                     /gene="appA"
                     /locus_tag="ACHY1N_003665"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acid phosphatase/4-phytase"
                     /protein_id="HFS4045889.1"
                     /translation="MKAILIPFLSLLIPLTPQSAFAQSESELKLESVVIVSRHGVRAP
                     TKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQP
                     GQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNA
                     NVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSKLCLNREKQDESCSLTQALPS
                     ELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQF
                     YLLQRTPEVARSRATPLLDLIMTALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGG
                     ALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNT
                     PPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL"
     gene            complement(11700..13880)
                     /gene="etk"
                     /locus_tag="ACHY1N_003666"
     CDS             complement(11700..13880)
                     /gene="etk"
                     /locus_tag="ACHY1N_003666"
                     /EC_number="2.7.10.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HFS4045890.1"
                     /translation="MTTKNMNTPPGSTQENEIDLLRLVGELWDHRKFIISVTALFTLI
                     AVAYSLLSTPIYQADTLVQVEQKQGNAILSGLSDMIPNSSPESAPEIQLLQSRMILGK
                     TIAELNLRDMVEQKYFPIVGRGWARLTKEKPGELAISWMHIPQLNGQDQQLTLTVGEN
                     GHYTLEGEEFTVNGMVGQRLEKDGVALTIADIKAKPGTQFVLSQRTELEAINALQETF
                     TVSERSKESGMLELTMTGDDPQLITRILNSIANNYLQQNIARQAAQDSQSLEFLQRQL
                     PEVRSELDQAEEKLNVYRQQRDSVDLNLEAKAVLEQIVNVDNQLNELTFREAEISQLY
                     KKDHPTYRALLEKRQTLEQERKRLNKRVSAMPSTQQEVLRLSRDVEAGRAVYLQLLNR
                     QQELSISKSSAIGNVRIIDPAVTQPQPVKPKKALNVVLGFILGLFISVGAVLARAMLR
                     RGVEAPEQLEEHGISVYATIPMSEWLDKRTRLRKKNLFSNQQRHRTKNIPFLAVDNPA
                     DSAVEAVRALRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQSDQKVLFI
                     DADLRRGYSHNLFTVSNEHGLSEYLAGKDELNKVIQHFGKGGFDVITRGQVPPNPSEL
                     LMRDRMRQLLDWANDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFGLNTAKEVS
                     LSMQRLEQAGVNIKGAILNGVIKRASTAYSYGYNYYGYSYSEKE"
     gene            complement(13900..14346)
                     /gene="etp"
                     /locus_tag="ACHY1N_003667"
                     /gene_synonym="yccY"
     CDS             complement(13900..14346)
                     /gene="etp"
                     /locus_tag="ACHY1N_003667"
                     /gene_synonym="yccY"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine-phosphatase Etp"
                     /protein_id="HFS4045891.1"
                     /translation="MAQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGL
                     VKHPADATAADVAANHGVSLEGHAGRKLTAEMARNYDLILAMESEHIAQVTAIAPEVR
                     GKTMLFGQWLEQKEIPDPYRKSQDAFEHVYGMLERASQEWAKRLSR"
     gene            complement(14334..15473)
                     /gene="gfcE"
                     /locus_tag="ACHY1N_003668"
     CDS             complement(14334..15473)
                     /gene="gfcE"
                     /locus_tag="ACHY1N_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015774 - polysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HFS4045892.1"
                     /translation="MKKNIFKFSVLTLAVLSLTACTLVPGQNLSTSNKDVIELPDNQY
                     DLDKMVNIYPVTPGLIDQLRAKPIMSQANPELEQQIANYEYRIGIGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNADGAIFYPYIGRLKVAGKTLTQVRNEITARLDSVIESPQ
                     VDVSVAAFRSQKAYVTGEVSKSGQQPITNIPLTIMDAINAAGGLTANADWRNVVLTQN
                     GVKTKVNLYALMQRGDLRQNKLLHPGDILFIPRNDDLKIFVMGEVGKQSTLKMDRSGM
                     TLAEALGNAEGMNQDVADATGIFVIRATQNKQNGKIANIYQLNAKDASAMILGTEFQL
                     EPYDIVYVTTAPLARWNRVISLLVPTISGVHDLTETSRWIQTWPN"
     gene            complement(15519..17615)
                     /gene="gfcD"
                     /locus_tag="ACHY1N_003669"
     CDS             complement(15519..17615)
                     /gene="gfcD"
                     /locus_tag="ACHY1N_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HFS4045893.1"
                     /translation="MKKNSYLLSCLAIAVSSACHAEVLTYPDPLGSSQSDFGGTGLLQ
                     MPNARIAPEGEFSVNYRDNDQYRFYSTSVALFPWLEGTIRYTDVRTRKYSQWEDFSGD
                     QSYKDKSFDFKLRLWEEGYWLPQVAFGKRDIAGTGLFDGEYLVASKQAGPFDFTLGMA
                     WGYAGNAGNITNPFCRVSDKYCHRAESHDAGDISFSDIFRGPASIFGGIEYQTPWNPL
                     RLKLEYDGNNYQNDFAGKLPQASHFNVGAVYRAASWADLNLSYERGNTLMFGFTLRTN
                     FNDLRPALRDTPKPAYQPAPESEGLQYTTVANQLTALKYNAGFDAPEIQLRDKTLYMS
                     GQQYKYRDSREAVDRANRILVNNLPQGVEKISVTQKREHMAMVTTETDVASLRKQLAG
                     TAPGQSEPLQQQRVEAEDLSAFGRGYRIREDRFSYSFNPTLSQSLGGPEDFYMFQLGL
                     MSSARYWFTDHLLLDGGIFTNIYNNYDKFKSSLLPADSTLPRVRTHIRDYVRNDVYLN
                     NLQANYFADLGNGFYGQVYGGYLETMYAGVGSELLYRPLDASWALGVDVNYVKQRDWD
                     NMMRFTDYSTPTGFVTAYWNPPTLNGVLMKLSVGQYLAKDKGATIDVAKRFDSGVAVG
                     VWAAISNVSKDDYGEGGFSKGFYISIPFDLMTIGPNRNRAVVSWTPLTRDGGQMLSRK
                     YQLYPMTAEREVPVGQ"
     gene            complement(17615..18361)
                     /gene="gfcC"
                     /locus_tag="ACHY1N_003670"
     CDS             complement(17615..18361)
                     /gene="gfcC"
                     /locus_tag="ACHY1N_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC D2 domain-containing
                     protein"
                     /protein_id="HFS4045894.1"
                     /translation="MNKLQSYFIASVLYVMTPHAFAQGTVTIYLPGEQQTLSVGPVEN
                     VVQLVTQPQLRDRLWWPGALLTDSAAKAKALKDYQHVMAQLASWEAEADDDVAATIKS
                     VRQQLLNLHITGRLPVKLDPDFVRVDENSNPPLVGDYTLYTVQRPVTITLLGAVSGTG
                     QLPWQAGRSVTDYLQDHPRLAGADKNNVMVITPEGETVVAPVALWNKRHVEPPPGSQL
                     WLGFSAHVLPEKYADLNDQIVSVLTQRVPD"
     gene            complement(18358..19002)
                     /gene="gfcB"
                     /locus_tag="ACHY1N_003671"
     CDS             complement(18358..19002)
                     /gene="gfcB"
                     /locus_tag="ACHY1N_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein GfcB"
                     /protein_id="HFS4045895.1"
                     /translation="MRPLILSIFALFLAGCTHSQQSMVDTFRASLFDNQDITVADQQI
                     QALPYSTMYLRLNEGQRIFVVLGYIEQEQSKWLSQDNAMLVTHNGRLLKTVKLNNNLL
                     EVTNSGQDPLRNALAIKDGSRWTRDILWSEDNHFRSATLSSTFSFAGLETLNIAGRDV
                     LCNVWQEEVTSTLPEKQWQNIFWVDSATGQVRQSRQMLGAGVIPVEMTFLKPAP"
     gene            complement(19109..19414)
                     /locus_tag="ACHY1N_003672"
     CDS             complement(19109..19414)
                     /locus_tag="ACHY1N_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309170.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045896.1"
                     /translation="MKHKLSAILMAFMLTTPAAFAAPEAANGTEATTGTTGTTTTTTG
                     ATTTAATTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTTR"
     gene            complement(19856..20068)
                     /gene="cspH"
                     /locus_tag="ACHY1N_003673"
     CDS             complement(19856..20068)
                     /gene="cspH"
                     /locus_tag="ACHY1N_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspH"
                     /protein_id="HFS4045897.1"
                     /translation="MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEV
                     LIPGLRVEFCRVNGLRGPTAANVYLS"
     gene            20354..20566
                     /gene="cspG"
                     /locus_tag="ACHY1N_003674"
     CDS             20354..20566
                     /gene="cspG"
                     /locus_tag="ACHY1N_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspG"
                     /protein_id="HFS4045898.1"
                     /translation="MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRT
                     LNENQKVEFSIEQGQRGPAAANVVTL"
     gene            20577..20765
                     /gene="ymcF"
                     /locus_tag="ACHY1N_003675"
     CDS             20577..20765
                     /gene="ymcF"
                     /locus_tag="ACHY1N_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4045899.1"
                     /translation="MTQHLHFRCPCCHGSQYRTSAFDVTERNPLGAKCIFCKSTMITF
                     DNVALQIRTDHAPLDFTK"
     gene            20740..20970
                     /gene="ymcE"
                     /locus_tag="ACHY1N_003676"
     CDS             20740..20970
                     /gene="ymcE"
                     /locus_tag="ACHY1N_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmcE"
                     /protein_id="HFS4045900.1"
                     /translation="MRRWISQNNIRLPRGAFFISALFFFNAVCIVSDNLLIIESFREM
                     AYNISYLTRGPGTNTLLACCCLLRPEEVNSEY"
     gene            20960..21133
                     /gene="gnsA"
                     /locus_tag="ACHY1N_003677"
     CDS             20960..21133
                     /gene="gnsA"
                     /locus_tag="ACHY1N_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HFS4045901.1"
                     /translation="MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKM
                     TGLESYDVKIKIM"
     gene            complement(21182..22255)
                     /gene="yccM"
                     /locus_tag="ACHY1N_003678"
     CDS             complement(21182..22255)
                     /gene="yccM"
                     /locus_tag="ACHY1N_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFS4045902.1"
                     /translation="MAENKRTRWQRRPGTTGGKLPWNNWRNATTWRKATQLLLLAMNI
                     YIAITFWYWVRYYETANSTTFVARPGGIEGWLPIAGLMNLKYSLTTGQLPSVHAAAML
                     LLVAFIVISLLLKKAFCSWLCPVGTLSELIGDLGNKLFGRQCVLPRWLDIPLRGVKYL
                     LLSFFLYIALLMPAQAIHYFMLSPYSVVMDVKMLDFFRHMGTATLISVTVLLIASLFI
                     RHAWCRYLCPYGALMGVVSLLSPFKIRRNAESCIDCGKCAKNCPSRIPVDKLIQVRTV
                     ECTGCMTCVESCPVASTLTFSLQKPAANKKAFALSGWLMTLLVLGIMFAVIGYAMYAG
                     VWQSPVPEELYRRLIPQAPTIGH"
     gene            complement(22327..25071)
                     /gene="torS"
                     /locus_tag="ACHY1N_003679"
     CDS             complement(22327..25071)
                     /gene="torS"
                     /locus_tag="ACHY1N_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415513.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HFS4045903.1"
                     /translation="MNLTLTRRLWMGFALMALLTLTSTLVGWYNLRFISQVEKDNTQA
                     LIPTMNMARQLSEASAWELFAAQNLTSADNEKMWQAQGRMLTAQSLKINALLQALREQ
                     GFDTTAIEQQEQEISRSLRQQGELVGRRLQLRQQQRQLSQQIVAAADEIARLAQGQAN
                     NATTSAGATQAGIYDLIEQDQRQAAESALDRLIDIDLEYVNQMNELRLSALRVQQMVM
                     NLGLEQIQKNAPTLEKQLNNAVKILQRRQIRIEDPGVRAQVATTLTTVSQYSDLLALY
                     QQDSEISNHLQTLAQNNIAQFAQFSSEVSQLVDTIELRNQHGLAHLEKASARGQYSLL
                     LLGMVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDIDSPFPETAGVRELDTIG
                     RLMDAFRSNVHALNRHREQLAAQVKARTAELQELVIEHRQARAEAEKASQAKSAFLAA
                     MSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAG
                     GKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATAIADDVPSALMGDPRRIRQVI
                     TNLLSNALRFTDEGQIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG
                     GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVATAPEPKTANQAVRLDGL
                     RLLLIEDNPLTQRITVEMLNTSGAQVVAVGNAAQALETLQNSEPFAAALVDFDLPDID
                     GITLARQLVQQYPSLVLIGFSAHVIDETLRQRTSSLFRGIIPKPVPREVLGQLLAHYL
                     QLQANTDQPLDVSQLNEDAQLMGTEKIHEWLVLFTQHALPLLDEIDIARASQDSEKIK
                     RAAHQLKSSCSSLGMCSASQLCAQLEQQPLSAPLPHEEITRSVAALEAWLHKKDLNAI
                     "
     gene            complement(25166..26239)
                     /locus_tag="ACHY1N_003680"
     CDS             complement(25166..26239)
                     /locus_tag="ACHY1N_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4045904.1"
                     /translation="MGRRRSHERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIA
                     ITEAIQANIELLSDSGRKSLIDRIKGGDAITLHVWLDRYETILTERGIRPKTLLDYAS
                     KIRAIRRKLPDKPLTDISTKEVAAMLNTYVAEGKAASAKLIRSTLVDVFREAIAEGHV
                     ATNPVTATRTAKSEVRRSRLTANEYVEIYHAAEPLPIWLRLAMDLAVVTGQRVGDLCR
                     MKWSDINDNHLHIEQSKTGAKLAIPLTLTIDALNISLADTLQKCREASSSETIIASKH
                     YDPLSPKTVSKYFTKARNASGLSFDGNPPTFHELRSLSARLYRNQIGDKFAQRLLGHK
                     SDSMAARYRDSRGREWDKIEIDK"
     gene            complement(26217..>26384)
                     /locus_tag="ACHY1N_003681"
     CDS             complement(26217..>26384)
                     /locus_tag="ACHY1N_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001325331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFS4045905.1"
                     /translation="LETVRRWVRECRIFPPPVKDGREYLFHESAVKVDLNRPVTGSLL
                     KRIRNGKKAKS"
BASE COUNT         6226 a         6682 c         6809 g         6667 t
ORIGIN      
        1 ttagatgtaa tctgacagat acctgtataa ataaccggta actgtcaggt cagagctaat
       61 acaggtaatt atattataat cacgagcgct tagatgtatt aataccatgc tctgcaagat
      121 gctgcatcag acgctgagcc acatcaggca gaggtcttga ttgttcattt tgtaccggcg
      181 gcgttggcgc aggccagtta ggtgccggag gaatatattc agccatattc cgggctggtt
      241 gaatgccatg ctctgcaaga tgctgcatca gacgctgagc cacatcaggc agaggtcttg
      301 attgttcatt ttgtactggc ggtggtggcg caggccagtt aggtgccgga ggaatatgtt
      361 cagccatatt ccgggctggt tgaatgccat gctctgcaag atgctgcacc agacgctgag
      421 ccacatcagg tagaggccga tgtaaagcgt ttttttctat acttgactga gtataagatg
      481 tgggacgttg aagtcctgat tctgtataag aattttttac cttaaaaata gttgttgcac
      541 tggcaggact gttgctggga gaaaaaggtg agctggtttt taccgtgtta ggtgtgcttt
      601 tgtgctgcga gacagtgaag gtactgctgc gtatagcact tgatatactg cgaggaaggc
      661 tggaaaaaaa agaattaatg ctatttatca tatagataac cttataagag ctttattgga
      721 tagtcttatt tatccgttta catgaaatct accttttgtg aaattctcgt caatatttta
      781 ctcaaaatga tcggctgtag gaataaacta tttgatatta ttacgttttt agggttgttt
      841 tcaatcagct atagataggg cttggcgcca gaatggagaa tatttaacga ggaatagaag
      901 ctttgtatca gacgggcttc cctaaataga gaagttaaat aatcaggatg atgctaatga
      961 atatcaggga caaggtgagt gtcttcatgt tcagtgaaac agggtgtcac aaaaaagatt
     1021 ggggggggct agagccttct gcacgaaaat agtgatgcga cagatctgag atagctttgt
     1081 atccttctgc ctggttcagg cctagagcag tccatgtttt acaaaaatac tcggcagcgt
     1141 aacgtgttgc aagagcggca tcagacgagg aacctgaggt tccgctcatg accgataatc
     1201 tcatccgaat aaaaatatac caattggtat accaagttta taccaagagc caaaaaagca
     1261 aaggggctac catttggtaa ccccttgatt atttggcgga agcgcagaga ttcgaactct
     1321 ggaacccttt cgggtcgccg gttttcaaga ccggtgcctt caaccgctcg gccacacttc
     1381 cggaatgacg cgcactataa acatcccgat gcggcgtgta aacccctaat ttgtttgttt
     1441 gcctgaaaaa cagccaaaag tgcattgata gcgtgaaata acagcagatt gatcatttca
     1501 tcaccatgaa ttccttctct tttactcgtt tagcaactgg ctaaacatcc ccaccgcccg
     1561 gcaaaaagaa aaataggtcc atttttatcg ctaaaagata aatccacaca gtttgtattg
     1621 ttttgtgcaa aagtttcact acgctttatt aacaatactt tctggcgacg tgcgccagtg
     1681 cagaaggatg agctttcgtt ttcagcatct cacgtgaagc gatggtttgc cttgctacag
     1741 ggacgtcgct tgccgaccat aagcgcccgg tgtcctgccg gtgtcgcaag gagaagagac
     1801 gtgcgatatg aataacgagg aaacatttta ccaggccatg cggcgtcagg gcgttacccg
     1861 acgcagcttt ctcaaatatt gcagtctggc tgccacgtcg ctgggattag gcgcgggaat
     1921 ggcaccaaag attgcctggg cgctggagaa caaaccgcgc attccggtgg tatggatcca
     1981 cggtctggaa tgcacctgct gtaccgaatc ttttatccgc tccgctcacc cactggcaaa
     2041 ggacgtcatc ctttccctga tttccctcga ttacgacgat actttgatgg ctgccgccgg
     2101 aacccaggcg gaagaagtct ttgaagacat catcgcgcaa tacaatggca aatatatcct
     2161 cgcagtagaa ggtaatccgc cgctgggcga gcaggggatg ttctgtatca gcagcggtcg
     2221 accgtttatt gagaaactca aacgtgccgc tgccggagcc agcgcgatta tcgcctgggg
     2281 aacctgcgcg tcctggggct gcgtgcaggc cgcgcgacct aatccgacgc aggcaacgcc
     2341 tatcgacaaa gtcatcaccg acaaacccat tatcaaagta cctggctgcc cgccgatccc
     2401 ggatgtgatg agcgccatca ttacttacat ggtgaccttt gatcgcttgc cagatgtcga
     2461 cagaatgggc cgtccattga tgttctatgg tcagcgaatc cacgataaat gctatcgccg
     2521 cgcccacttc gacgccggag agttcgtcca gagttgggat gatgacgctg cccgcaaagg
     2581 ttactgtctg tacaaaatgg gctgcaaagg gcctaccacc tataacgcct gttcctccac
     2641 acgctggaat gatggcgttt ctttcccaat ccagtctggt cacggctgcc tgggttgtgc
     2701 ggaaaatggt ttctgggatc gcggttcgtt ctacagccgc gtggtcgata ttccgcaaat
     2761 gggtactcat tccaccgccg ataccgtcgg tttaaccgcg cttggcgtgg tggcagcggc
     2821 tgttggtgtg cacgcagtcg ccagcgccgt tgaccagcgc agacgtcata accagcaacc
     2881 tacagaaact gaacatcagc caggcaatga ggataaacag gcatgagcac tcagtacgaa
     2941 actcagggat acaccatcaa taatgccgga cgccgcctgg tggtcgaccc gattacgcgc
     3001 attgaaggcc acatgcgctg cgaagtgaat attaacgatc agaatgtgat caccaatgcc
     3061 gtctcctgcg gcaccatgtt tcgcgggctg gagatcatcc tgcaagggcg cgacccgcgc
     3121 gatgcgtggg cgttcgttga acgtatctgc ggcgtctgta ctggcgtaca cgccctggct
     3181 tcggtttacg ccatcgaaga tgccatcggt attaaagtgc cggacaacgc caatatcatc
     3241 cgcaacatta tgctggcaac gctctggtgc cacgatcatc tggtgcactt ctatcagctc
     3301 gccgggatgg actggatcga tgtgttagat gcgctgaaag ccgacccgcg gaaaacctcc
     3361 gaactggcgc aaagtctctc ctcatggccg aaatcatccc ctggctattt cttcgacgta
     3421 caaaaccgcc tgaaaaaatt tgttgaaggc gggcagttgg ggatcttccg caatggctac
     3481 tgggggcacc cgcagtacaa actgccgcca gaagccaacc tgatgggctt tgcccactat
     3541 ctagaagctc tcgatttcca gcgtgaaatt gtcaaaatcc acgcggtctt tggcggtaaa
     3601 aacccgcatc caaactggat tgtcggcggg atgccttgcg ccattaacat tgacgaaagc
     3661 ggcgcggtcg gggcggtcaa tatggaacgc ctgaacctgg tgcagtcgat tatcacccgc
     3721 acggcagact tcattaacaa cgtgatgatc cccgacgcct tagccatcgg tcagtttaac
     3781 aaaccgtgga gcgaaatcgg cacgggtctt tctgataaat gtgtcctcag ctacggcgca
     3841 ttcccggata ttgccaacga ctttggtgag aaaagtctgc tgatgcctgg cggcgcggtg
     3901 attaacggcg acttcaacaa tgtgctgcca gtggatttgg ttgatccgca gcaggtgcag
     3961 gagtttgtcg accacgcctg gtatcgttat cccaacgatc aggtcgggcg tcatccattc
     4021 gatggcatta ccgacccgtg gtacaacccc ggcgatgtca aaggcagcga taccaacatt
     4081 cagcagctga atgaacagga acgctactcg tggatcaaag cgccgcgctg gcgcggtaac
     4141 gcgatggaag tggggccgct ggcacgcacc ttaatcgctt atcacaaagg cgatgctgcg
     4201 accgttgagt cggtcgatcg catgatgtcg gcgctgaacc tgccgctttc cggtatccag
     4261 tcaacgttgg gccgcatttt gtgccgcgcg cacgaagcac agtgggccgc aggtaagttg
     4321 cagtatttct tcaacaagct gatgaccaac ctgaaaaacg gcaatctcgc cactgcttcc
     4381 acggaaaaat gggaacctgc aacttggccg acagagtgcc gtggtgtcgg ttttaccgaa
     4441 gcgccgcgcg gggcgttagg ccactgggcc gccattcgcg atggcaagat tgatctctac
     4501 cagtgcgtgg tgccgaccac ctggaacgcc agcccgcgcg atcccaaagg gcagattggc
     4561 gcttatgaag cagcgctgat gaacaccaaa atggcgatcc ccgagcaacc gctggagatc
     4621 ctgcgtactc tgcacagctt tgatccgtgc ctcgcctgtt caacacacgt gctgggcgac
     4681 gacggtagcg agctgatctc cgtgcaggtg cgttaacagc gaaggagaat catcatgcaa
     4741 cagaaaagcg acaacgttgt cagccactat gtctttgaag cgccagtgcg tatctggcac
     4801 tggctgacgg tgttatgcat ggcggtgttg atggtcaccg gttactttat cggcaagccg
     4861 ctaccttccg tcagcggcga ggcgacgtat ctgttctata tgggctacat caggttaatt
     4921 cacttcagcg ccgggatgat ttttaccgtg gtcttgctga tgcggatcta ctgggctttt
     4981 gttggcaatc gatactcccg cgagctgttt atcgtgccgg tatggcgtaa aagctggtgg
     5041 cagggcgtgt ggtatgaaat ccgctggtat ctgcttctgg caaaacgtcc gagtgccgat
     5101 ataggccata accccatcgc ccaggcggcg atgttcggct atttcctgat gtcggtcttt
     5161 atgatcatca ctggctttgc gctgtacagc gaacacagcc agtacgctat ttttgcgccg
     5221 ttccgttatg tggtggaatt tttctactgg acgggcggca actcaatgga cattcacagc
     5281 tggcatcggc tggggatgtg gctgattggc gcatttgtga tcggtcatgt ctacatggcg
     5341 ctgcgtgaag acatcatgtc cgacgacacg gtgatctcca ctatggtcaa cggctaccgt
     5401 agccacaaat ttggcaaaat aagtaacaag gagcgttcat gagcgagcaa cgcgtggtgg
     5461 taatggggct gggcaacctg ctgtgggccg atgaaggctt cggcgtgcgg gtggcggaac
     5521 ggctgtatgc ccattaccac tggcccgagt atgtggagat tgtcgatggc ggtactcagg
     5581 gactgaactt gctggggtat gtcgaaagcg ccagccatct gttgattctc gatgccattg
     5641 actacgggct ggaacctgga acgctgcgaa cctatgccgg agaacgcatt ccggcttatc
     5701 tcagcgcgaa gaaaatgagc ctgcaccaga acagtttctc cgaagtgctg gcgctggcag
     5761 atatccgcgg acatctgcca gcacatattg ccctcgtcgg tctgcaaccc gcaatgctcg
     5821 acgactacgg cggcagcctg agcgaactgg cgcgggagca actgcccgct gcggaacaat
     5881 cggcgctggc gcaactggct gcgtggggaa ttgtgccgca accggctaat gaatcgcgct
     5941 gtctcaatta tgactgtctg tcgatggaaa attacgaagg cgttcgcttg cgccagtacc
     6001 ggatgacaca ggaggagcag ggatgagcaa cgacacgcca tttgatgcgt tgtggcaacg
     6061 aatgctggcg cgcggctgga cgccggtcag tgaatcccgt cttgacgact ggcttacgca
     6121 agcgccagac ggcgtggtgt tattaagcag tgacccgaaa cgtacgccag aggtcagcga
     6181 taatccggta atgattagcg aattactgcg cgagtttccc gactatacat ggcaggtggc
     6241 gattgctgac cttgagcaga gcgaagccat cggcgatcgc tttggcgtct ttcgctttcc
     6301 cgccacttta gtgtttaccg gcggaaacta tcgcggtgtg ctgaatggta ttcacccgtg
     6361 ggcggaactg ataaacctga tgcgcgggct tgtcgaaccg cagcaggagc gtgcctcatg
     6421 agcgaaactt ttttccatct gctggggcca ggaacgcaac cgaacgatga cagtttcagc
     6481 atgaatccac tgccgatcac ctgtcaggtg aatgatgaac cgagtatggc ggccctggag
     6541 caatgtgctc acagcccgca ggtgattgcg ctgttaaacg agttacaaca tcaactaagc
     6601 gaacgccagc cgccgttggg cgaggtgctg gcagtcgatc tgttaaatct caacgccgac
     6661 gatcgtcact ttatcaatac gcttctcggg gaaggggaag tgtcagtgcg cattcagcag
     6721 gttgacgaca gtgaaagtga aatacaggag gcgatcttct gcggattatg gcgggtgcgc
     6781 agacgtcgcg gcgaaaagtt gctggaggac aaactggagg ctggctgcgc gccgctggcg
     6841 ttgtggcagg cggcaacgca aaatctcttg ccgacagatt cgctgttacc gccgcccatt
     6901 gatggcctga tgaatggcct accgttggcg catgagttac tggcacatgt acgtaacccc
     6961 gacgcgcagc cgcacagcat taatctgacg caattaccca tcagcgaggc tgatcggctt
     7021 tttctctcac gtctctgtgg gccgggaaat attcagattc gtaccattgg ctatggcgag
     7081 agctatatca acgccacggg gttacgccat gtctggcatt tacgctgtac ggacacctta
     7141 aaaggcccgt tactggaaag ttatgaaatc tgcccaatac cggaagtggt gctggcagcg
     7201 ccagaagatt tggtcgactc tgcgcagcgg cttagcgagg tatgtcagtg gctggcggaa
     7261 gctgcaccga cgtaaaaaga cggtaagtat cgctttcagg cttatgaata tcgcaatcgg
     7321 cgaatacctc tggtcgtaga gtttcaggat aaagagggag atctaccatt atcgggttat
     7381 ttttctctct tcgcctacag gagtgcgcat gtgggatgtc attgatttat cgcgctggca
     7441 gtttgctctg accgcgctgt atcacttttt atttgtaccc cttaccctgg ggctgatttt
     7501 tttgctggct atcatggaaa ccatttacgt ggtcaccggc aaaacgatct accgcgatat
     7561 gacgcgcttc tggggtaagc tcttcggtat caactttgct cttggcgtgg ctaccggcct
     7621 gacgatggag tttcagtttg gtactaactg gtcattctat tccaactatg tgggcgatat
     7681 ttttggcgca ccactggcga tggaagcatt aatggccttc ttcctcgaat ccacctttgt
     7741 cgggctgttc ttcttcggct ggcaacggct gaataaatac cagcacctgc tggtgacgtg
     7801 gctggtggcg ttcggttcaa atctctctgc gttgtggata ttgaatgcca acggttggat
     7861 gcaatacccg accggtgcgc attttgatat cgacaccctg cgtatggaga tgaccagttt
     7921 cagcgagttg gtctttaacc cggtcagcca ggtgaaattt gtgcacaccg taatggcggg
     7981 ctacgtgacc ggggccatgt ttattatggc gatcagcgcc tggtatttac tgcgcggacg
     8041 ggagcgcgat gtcgcattac gctcgtttgc catcggttcc gtcttcggta ctctggcgat
     8101 tatcggtacc ctgcaactcg gagacagttc tgcgtatgaa gtcgcgcaag tacaaccggt
     8161 aaaactggcg gcgatggaag gggagtggca aacggaacct gcacctgcac cgttccatgt
     8221 ggttgcctgg ccggaacagg atcaagagcg taacgccttt gctatcaaaa ttcccgcgct
     8281 gctagggatc ctcgccactc actcattaga taaacccgtg ccgggtctga agaatttgat
     8341 ggctgaaacc tacccacgct tgcaacgcgg acgtatggcc tggctgttaa tgcaggaaat
     8401 atcgcaaggc aatcgtgagc cgcatgtgtt gcaggcattc cgggagctgg aaggcgacct
     8461 tggttacggc atgttgctct cccgctatgc gccggatatg aatcatgtca cagccgcaca
     8521 gtaccaggcg gcgatgcgtg gcgcgatacc tcaggttgcg ccggtattct ggagtttccg
     8581 catcatggtg ggctgtggtt ccctgctgct actggtgatg ctgattgcgc ttgtccagac
     8641 gctgcgtggc aaaatcgacc agcatcgctg ggtgctgaaa atggcgctct ggagtttgcc
     8701 gttgccgtgg attgcgattg aagccgggtg gtttatgacc gagtttggtc gtcagccgtg
     8761 ggcgatacag gacatcttac cgacatactc cgcgcactcc gctttaacca caggacaact
     8821 ggctttctca ctgatcatga tcgtagggct ttacaccctg ttcttaatcg ccgaagtcta
     8881 cctgatgcag aaatatgccc gtctggggcc gagcgcgatg cagagtgaac aaccgacgca
     8941 gcaacagggg taaaggagaa aatcatgttt gattatgaaa cattgcgctt catctggtgg
     9001 ctgctgattg gcgtgatcct ggtggtcttt atgatctccg acggatttga catggggatc
     9061 ggctgtttgc tgccgctggt ggcgcgtaat gatgatgaac gccggatagt gattaatagc
     9121 gttggtgcgc actgggaagg caatcaggtc tggttgatcc tcgcaggtgg agcattattt
     9181 gccgcctggc ccagagtgta tgcagcggcg ttttccggct tttatgtggc gatgatcctg
     9241 gtgctgtgct cactgttctt ccgcccgctg gcctttgatt atcgcggaaa aatcgccgat
     9301 gcacgctggc gtaaaatgtg ggatgccggt ctggtcatcg gcagtctggt gccgccggta
     9361 gtcttcggta tcgccttcgg caacttgctg ctcggcgtgc cgtttgcctt cacaccgcaa
     9421 ttacgcgtgg agtatctcgg cagcttctgg caactgctga cgccattccc tttattgtgc
     9481 ggattactca gccttgggat ggtgattttg caaggtggcg tctggttaca actgaaaact
     9541 gttggtgtga ttcatctgcg ttcacagctg gcgactaaac gcgccgcact actggtgatg
     9601 ctgtgctttt tgctggcggg ttactggctg tgggtcggta ttgatggctt tgtactgctc
     9661 gcccaggatg ctaacggtcc ttccaatccg ttaatgaaac tggtagcagt gctacctggt
     9721 gcctggatga ataatttcgt cgaatcgccc gttttgtgga tcttcccgct gctggggttc
     9781 ttctgcccat tgctgacggt gatggcgatt tatcgtggtc gcccgggttg gggattttta
     9841 atggcgtcat tgatgcaatt tggcgtgatt ttcacggcag gcatcacgct gttccccttt
     9901 gtcatgccgt caagcgtgag tccaatctcc agcctgacgt tgtgggacag cacttccagt
     9961 cagctgacgc tgagcattat gttggtaatc gtgctgatat ttttgcccat tgtgttgctc
    10021 tacactctct ggagctacta caaaatgtgg ggacgcatga cgacagaaac tctccgccgt
    10081 aacgaaaacg agctgtacta aggagcaggg acaatgtggt atttactttg gttcgtcggc
    10141 attttgttga tgtgttcgct ctccaccctt gtgttggtat ggctggaccc gcgattgaaa
    10201 agttaacgaa cgtaagcctg atgcggcgca ttagcgtcgc atcaggcaat aatgtcggat
    10261 atgaaaagcg gaaacatatc gatgaaagcg atcttaatcc catttttatc tcttttgatt
    10321 ccgttaaccc cgcaatctgc attcgctcag agtgagtcgg agctgaagct ggaaagtgtg
    10381 gtgattgtca gtcgtcatgg tgtgcgtgcc ccaaccaagg ccacgcaact gatgcaggat
    10441 gtcaccccag acgcatggcc aacctggccg gtaaaactgg gttggctgac accgcgcggt
    10501 ggtgagctaa tcgcttatct cggacattac caacgccagc gtctggtggc tgacggattg
    10561 ctggcgaaaa agggctgccc gcagcctggt caggtcgcga ttattgctga tgtcgacgag
    10621 cgtacccgta aaacaggcga agccttcgcc gccgggctgg cacctgactg tgcaataacc
    10681 gtacataccc aggcagatac gtccagtccc gatccgttat ttaatcctct aaaaactggc
    10741 gtttgccaac tggataacgc gaacgtgact gacgcgatcc tcagcagggc aggagggtca
    10801 attgctgact ttaccgggca tcggcaaacg gcgtttcgcg aactggaacg ggtgcttaat
    10861 tttccgcaat caaaattgtg ccttaaccgt gagaaacagg acgaaagctg ttcattaacg
    10921 caggcattac catcggaact caaggtgagc gccgacaatg tctcattaac cggtgcggta
    10981 agcctcgcat caatgctgac ggagatattt ctcctgcaac aggcacaagg aatgccggag
    11041 ccggggtggg gaaggatcac cgattcacac cagtggaaca ccttgctaag cctgcataac
    11101 gcgcagtttt atttgctgca acgcacacca gaggttgccc gcagtcgcgc caccccgttg
    11161 ttggatttga tcatgacagc gttgacgccc catccaccgc aaaaacaggc gtatggtgtg
    11221 acattaccca cttcagtgct gtttattgcc ggacacgata ctaatctggc aaatctcggc
    11281 ggcgcactgg agctcaactg gacgcttcca ggtcagccgg ataacacgcc gccaggtggt
    11341 gaactggtgt ttgaacgctg gcgtcggcta agcgataaca gccagtggat tcaggtttcg
    11401 ctggtcttcc agactttaca gcagatgcgt gataaaacgc cgctgtcatt aaatacgccg
    11461 cccggagagg tgaaactgac cctggcagga tgtgaagagc gaaatgcgca gggcatgtgt
    11521 tcgttggccg gttttacgca aatcgtgaat gaagcacgca taccggcgtg cagtttgtaa
    11581 tgcataaaaa agagcattca gttacctgaa tgctctgagg ctgatgacaa acgaagaact
    11641 gtctaatgcg tagaccggaa aaggcgttca cgccgcatcc ggtcacttta ccttcagttt
    11701 tactctttct cggagtaact ataaccgtaa tagttatagc cgtaactgta agcggtgctg
    11761 gcgcgtttaa tcacaccatt gaggattgcg cctttaatat taacgccagc ctgttccaga
    11821 cgctgcattg acaagctcac ctctttggcg gtgttcaggc caaaacgcgc aaccagcagg
    11881 ctggtgccga cagagcgtcc cacgaccgca gcatcgctca ccgccagcat cggcggcgta
    11941 tcgacaatca ccagatcgta atggtcgttc gcccaatcca gtaattgacg catccgatcg
    12001 cgcatcagca gttcagacgg gttaggtggc acctgaccgc gagtaatcac atcaaagcct
    12061 cctttgccaa aatgctggat cactttgttg agctcatctt tacctgccag atattccgac
    12121 aagccatgtt cattactcac tgtaaacagg ttatgcgaat aaccgcggcg taagtcggca
    12181 tcaataaata acactttttg atcggactgg gcgatcaccg ctgccagagt tgaactgaca
    12241 aacgttttac cactgtctgg cgtcgcaccg gtgatcatca gaatgttatt ctccgtctcc
    12301 atcatagcga agtgcagact ggttcgtagc gcacgtacgg cttccacagc agaatccgcc
    12361 gggttatcca cagccaggaa ggggatattt ttagtacgat ggcgctgctg attagaaaat
    12421 aaatttttct tacgcagacg ggtacgttta tccagccact cggacattgg gatagtggca
    12481 taaacgctga tgccgtgctc ttccagttgt tccggggctt ctacaccacg acgcaacatc
    12541 gcacgcgcca gcacggcacc caccgaaata aacaggccaa gaataaaacc aagcaccaca
    12601 ttcaacgctt ttttcggttt cactggctgc ggctgagtga ctgccgggtc gataatccgc
    12661 acgttaccaa tggcactgga tttcgaaata ctcaactcct gctggcggtt aagtaattgc
    12721 agatataccg cacggcccgc ttctacgtca cgacttaaac gcaacacttc ctgttgggtg
    12781 gaaggcatag ccgatacccg cttattcagg cgtttgcgtt cttgctccag cgtctggcgt
    12841 ttttccagca gcgcacgata agttgggtga tctttcttat acagctggga gatctctgcc
    12901 tcgcggaaag tcagctcatt gagttgatta tcaacgttca caatctgctc aagaacggct
    12961 ttggcttcca ggttaaggtc aaccgaatcg cgctgctggc gataaacgtt gagtttttct
    13021 tccgcctggt ccagctcgct gcgcacttca ggcaactggc gctgtaagaa ttcaaggctt
    13081 tgtgaatcct gcgccgcctg gcgagcgata ttctgttgca aatagttgtt agcgatgctg
    13141 ttcagaatac gagtaatcaa ctggggatca tcaccggtca tggtaagttc cagcatcccg
    13201 ctttctttac tgcgttcgct aacggtaaag gtttcctgca acgcgttaat cgcttccagt
    13261 tcggtacgtt ggctcaggac aaactgtgtt cctggtttgg ccttaatgtc cgcgatagtc
    13321 agcgcaacgc catctttttc cagacgctgg ccgaccatac cattgacggt gaactcttca
    13381 ccttccagcg tatagtggcc gttttcccca accgtgagtg tcagttgctg atcctgacca
    13441 ttcagttgtg gaatatgcat ccagctgatc gccagctcac ctggtttctc tttggttaat
    13501 ctcgcccagc cgcgacccac aatcggaaaa tacttttgct caaccatgtc acgcagattc
    13561 agttcagcaa tggttttacc gagaatcatg cgcgattgca gcagttggat ctccggtgca
    13621 gactcgggcg atgagttagg gatcatatcg ctcaggccgc tgagaatggc gttgccctgt
    13681 ttttgctcaa cctggaccag agtatctgcc tgataaattg gtgtgcttaa cagcgagtaa
    13741 gcgacagcga tcagcgtgaa taacgcggtc acgctgataa taaacttacg gtgatcccat
    13801 aactcgccga ccagacgaag cagatcgatc tcattttcct gagtgctgcc tggtggcgta
    13861 ttcatatttt tagttgtcat cgtattttat aaactcaaat taccggctga ggcgcttcgc
    13921 ccattcctga ctggcgcgct ccaacatacc gtagacatgt tcaaatgcgt cctgactttt
    13981 acgataggga tccgggatct ctttctgttc cagccattgc ccaaacagca ttgtcttccc
    14041 gcggacctcg ggagcgattg cggtaacctg agcaatatgt tccgactcca ttgccagaat
    14101 cagatcgtaa tttcgtgcca tctcagcagt gagcttacgt ccggcatgtc cttcaagaga
    14161 tacgccatga ttagcggcaa catctgccgc tgtcgcatct gcagggtgtt ttaccagacc
    14221 atgaacacct gccgatttga cttttacgcc cggcagacgt ttacgcagca agcgctcgcc
    14281 aatgggcgaa cggcaaatgt tgccggtaca aaccaccagg attgagttaa attttagttg
    14341 ggccatgttt gaatccaccg tgaagtctct gtcaggtcat gcaccccgga aatcgtcggt
    14401 accagcagag aaatcacacg gttccaacga gccagcggcg cggtagtgac ataaacaatg
    14461 tcgtaaggtt caagctggaa ttccgttccg agtatcattg ccgatgcgtc cttcgcattc
    14521 agctgataaa tattggcgat ttttccattc tgcttgtttt gcgttgcacg aataacaaaa
    14581 atccccgtcg catcagcgac atcctgattc ataccctcag cgttacccag cgcttccgcc
    14641 agggtcatac cgctgcggtc cattttcagc gtgctctgtt tacccacttc acccatcacg
    14701 aagattttca gatcatcgtt gcgcggaata aataaaatat cgcccgggtg cagcagtttg
    14761 ttctgacgca agtcgccacg ctgcatcagc gcatagaggt tcactttggt ctttacgcca
    14821 ttctgggtga gcaccacatt gcgccagtct gcatttgcgg tcagaccgcc cgcggcgtta
    14881 atcgcatcca tgatggtcag aggaatattg gtaatcggct gctgacccga tttgctgact
    14941 tcgccggtga cgtacgcttt ttgcgatcgg aacgctgcga cgctgacatc gacctgcggg
    15001 ctttcaatga ctgaatcgag acgcgctgta atctcgttgc gtacctgggt aagtgttttc
    15061 ccggccactt tcaggcgacc aatatagggg tagaaaatcg caccatcggc gttaacccag
    15121 ttgccggtat cactggcgct acggtattgc cctgcggggg tggttagttc cgggtgatcc
    15181 cagaccgtaa ccatcaacac atcaccaatg ccgatacgat attcatagtt cgcgatttgc
    15241 tgctccagct ccgggttagc ctgcgacata atcggtttgg cgcgcagctg atcaatcaat
    15301 cctggcgtga cgggatagat attgaccatt ttgtccaggt catactgatt gtcaggtagt
    15361 tcaatgacat ccttgttact ggtcgataaa ttctgaccag gaacaagggt acatgctgtc
    15421 aaagacagaa cagccaatgt cagtaccgaa aacttaaaaa tgttcttttt cattggttta
    15481 tatttatcag tcaatgtaat gttatgaatt acgtcaggtt attgtccaac cggtacttct
    15541 cgctctgccg tcattggata gagctggtat ttgcgtgaca gcatttgtcc accatcacgc
    15601 gtcaatggtg tccacgaaac caccgcgcgg ttgcggttag gtccaatggt catcaagtcg
    15661 aacggaatcg agatataaaa acctttacta aagccgcctt cgccgtagtc atctttagat
    15721 acgttactga ttgccgccca tacccctacc gccacgccgc tgtcaaagcg tttggcgacg
    15781 tcgatcgttg cccctttatc ttttgccaga tattgcccaa cgctaagttt catcagtacg
    15841 ccattgagcg tcggcgggtt ccagtaagcc gtcacgaaac ctgttggcgt ggaataatcg
    15901 gtgaagcgca tcatgttgtc ccagtcacgt tgcttcacgt agttaacgtc cacacccagc
    15961 gcccagctgg catctagcgg gcgataaagc agctcggaac cgacaccggc gtacatcgtt
    16021 tccagataac cgccatacac ctggccatag aaaccattgc ctaagtcggc aaagtagttc
    16081 gcctgcaagt tgttgagata aacgtcattg cgaacgtaat cacggatatg cgtgcgcacg
    16141 cggggcaggg tagagtccgc gggtaatagc gaagacttaa acttgtcgta gttattgtaa
    16201 atattggtga aaataccgcc atcaagcagc aggtggtcag taaaccagta gcgggcgctg
    16261 gacatcagcc ccaactggaa catatagaaa tcttccgggc cgcccagcga ctgtgaaagt
    16321 gttgggttga aagagtagct aaagcgatct tcacgaatac ggtagccccg accaaaggca
    16381 gaaagatctt cagcttcaac acgttgttgt tgcagtggct ctgattgacc aggcgctgta
    16441 ccggccagct gtttgcgcag gctggctacg tcggtttcgg tagtcaccat agccatatgc
    16501 tcgcgctttt gcgtcacgct aatcttctca acgccttgcg gcaggttatt caccagaatc
    16561 cggttggcac gatcgaccgc ttcacgagag tcacggtatt tgtattgctg accagacata
    16621 tacagcgtct tatcgcgtag ctgaatttct ggcgcgtcaa agcccgcgtt atacttcagg
    16681 gcggtaagtt ggtttgctac cgtggtgtac tgcaatcctt cagattcagg cgcaggttga
    16741 tatgccggtt ttggcgtatc gcgcagggca gggcgcagat cgttgaaatt ggtccgtaaa
    16801 gtgaaaccaa acatcaacgt gttaccgcgt tcataactca ggttgaggtc tgcccagctg
    16861 gcagcgcgat aaactgcacc gacgttgaaa tggcttgcct gaggcagttt gccagcgaaa
    16921 tcattctggt aattgttgcc gtcgtattcg agtttcagac gcaggggatt ccacggcgtt
    16981 tgatactcaa tgccgccaaa gatggaagcc gggccacgaa agatatcgct aaagctgata
    17041 tcgcccgcat cgtgagactc tgcgcgatga caatatttat cgctcacccg gcaaaacggg
    17101 ttggtaatat tgcccgcatt accggcgtag ccccatgcca tcccgagggt gaaatcaaat
    17161 ggccccgctt gcttgctggc caccagatac tcaccgtcaa acagacccgt accagcaata
    17221 tcacgtttac caaacgctac ttgcggtagc cagtaacctt cttcccatag gcgaagttta
    17281 aaatcgaaag atttgtcttt gtatgactga tcgccgctga aatcttccca ctggctatat
    17341 ttgcgtgtgc gcacatccgt ataacgaatg gtgccttcca gccatgggaa cagcgccacg
    17401 gaggtggagt agaaacggta ttgatcgtta tcccggtagt tgacgctgaa ttcaccttcc
    17461 ggtgcgatgc gcgcatttgg catctgcaac aatcctgtgc cgccaaagtc tgattgcgac
    17521 gaacccagcg gatccgggta ggttaatact tcagcatgac aggcactgga gacggcaatg
    17581 gccaggcagc ttaaaagata agaattcttc ttcatcagtc aggaacacgt tgcgttaaaa
    17641 cagacacaat ctggtcattt aaatcagcat atttttcggg cagtacatgc gcagaaaagc
    17701 ccaaccaaag ctggctgcca ggcggtggtt ccacatgtct tttattccac agggcaacag
    17761 gggcgacgac agtctcaccc tcaggcgtaa tcaccataac gttattcttg tccgcgcctg
    17821 caaggcgggg gtgatcttgc agataatcgg taacgctacg gcctgcctgc cagggcaatt
    17881 gcccagtccc agaaaccgca cccagcagag taatagtcac cggacgctgt acggtataga
    17941 gcgtatagtc cccgaccagc gggggattgc tgttctcatc cactcgtaca aaatcagggt
    18001 ccagtttgac cggtaagcga ccagtgatat ggagattgag taactgctgg cgcacggatt
    18061 taatcgttgc tgccacatcg tcgtcagctt ctgcttccca ggaagcaagc tgtgccatga
    18121 catgttggta gtctttaagc gctttagctt tcgccgcaga gtcggtcagc aaggcaccag
    18181 gccaccagag gcgatcgcgc agttgcggtt gtgtcaccaa ctggacaaca ttttccacgg
    18241 ggccaacgga aagtgtctgt tgttcgccag gcagataaat agtcaccgtt ccttgcgcaa
    18301 aggcatgggg tgtcattacg taaagtacgc tggcaatgaa atacgactgt aatttattca
    18361 tggtgcgggt ttaagaaacg tcatttctac gggaataacc cctgcgccta acatttgtcg
    18421 actttgacga acctggccag tagccgaatc gacccagaat atgttttgcc actgtttttc
    18481 tggcagcgtg gaagtcacct cttcctgcca gacattacac agcacatcgc gacccgcaat
    18541 attcagcgtc tctaatccag caaaggaaaa agtggaactc agggtcgcag agcgaaaatg
    18601 gttgtcttca ctccagagaa tatcgcgcgt ccagcggctg ccgtctttta ttgccagcgc
    18661 gttacgcaga gggtcctgcc cggaatttgt cacttccagc agattattat taagtttgac
    18721 ggtctttaaa agacgtccat tatgggtaac cagcatggcg ttatcctggg ataaccattt
    18781 gctttgttct tgttctatat atcccagtac cacaaagatt cgttgccctt cattaaggcg
    18841 taaatacatc gtggaataag gcaacgcctg gatctgctga tccgctacgg tgatatcctg
    18901 attatcgaaa aggctggcgc gaaatgtatc gaccatactt tgctggctgt gcgtacatcc
    18961 cgcaagaaat agtgcgaaaa tcgataaaat aagagggcgc acctttaatc cttgaaaggt
    19021 taattaaaaa aatgcaaatc tctaaagccc ggtacgaata tcgcaaccgg gtattattta
    19081 actttaattt cgacgcgttt aagcagaatt agcgcgtagt ggacgtggtg gttgaggtgt
    19141 tatgagaacc gccatcgcca ctgtcatttg ctgcaactac tgccaacgtc gccacaccaa
    19201 cagccgttgc cacaccgaca actgtcgccg tgccgacagc gccagcagcc acgccaccag
    19261 tggtagcagc cgtcgtggtt gcaccggtag tggtcgttgt ggtgccagta gtacccgtcg
    19321 ttgcctcggt cccgtttgct gcttcagggg cagcaaacgc agctggcgtc gtcaacatga
    19381 aggccataag gattgcagaa agcttgtgtt tcataacttt tcctttattc atcgcatgga
    19441 caatacgtac gcttgagatc aggattgtct actttgagta taacatcctt gtgaaatctc
    19501 cctttcctca taccgcttgc actatataca gcgggtgaga aaggcgcgca gagggaaata
    19561 taagattgtt aacgatttcc ctctggaaat acgacttgtg agcataagat aaatcttaga
    19621 aaaatacaaa ttaaagataa gaaaattgtt aagaaagcta ttaactattg ttgataatat
    19681 agtttcaagc ggtactataa ctggctgtta agtggcattt ataactatta gttgcagaga
    19741 tattcggtta aatggattag tttcctgata aaaaagtaac ttgcgttata atgcatggtg
    19801 ttgactattg aactattcca ataaaaccag tcagctttaa acaagcagcg tcatattaag
    19861 agagataaac atttgccgct gttggtcctc gcaggccatt tacgcgacaa aattccacgc
    19921 gtaatcctgg tataagcact tctgcgtcgc ggggagtgaa tgcggaaata tggacctgga
    19981 cttctttacg accgtcggag gggataatga atcctttgcc gcttttgcga tcaaaggttt
    20041 tgacaattcc tgtcatttta cgggacaaac aaattcctta ctgaaaatac tgcgctgcac
    20101 tatacggggt taataaaata aagccagcga aatttaagac cgccggacgg ctaaaataaa
    20161 atttgcttaa tctcaattat catgcgttaa tagctgcgtc ggtttgaaag acagacagca
    20221 tacaaagtag tttactaaag cagttctcat tatcaggcat tatccccttc ttttgagtct
    20281 ctctcctgaa cactaagtag tttctgtatt aaagccctgt ttgccgaaag gcccaaaatg
    20341 aaggaagtaa aatatgtcta ataaaatgac tggtttagta aaatggttta acgcagataa
    20401 aggttttggc tttatcactc ctgatgatgg cagcaaagac gttttcgtcc atttcaccgc
    20461 catccagagc aatgaattcc gcacgctgaa cgaaaatcag aaagttgaat tttctattga
    20521 gcaggggcaa cgtggccccg cggcagcgaa cgttgttacg ctctaaggtt gccgttatta
    20581 ctcaacatct ccatttccgc tgtccatgtt gtcatggttc acagtaccgc acatcggcat
    20641 tcgatgtgac ggagcgaaac cctttgggcg ctaagtgtat tttttgtaaa tcgacaatga
    20701 tcacctttga taacgtcgcg ctgcaaatac gcactgacca tgcgccgctg gatttcacaa
    20761 aataatatca ggctccctcg tggagccttt tttatatctg ccttattttt cttcaacgct
    20821 gtatgtatag taagcgataa cctgttgatt attgaatctt tcagggagat ggcttataac
    20881 atttcttacc tgaccagggg accgggaacc aacaccttac tggcgtgttg ctgtctttta
    20941 agaccagaag aggttaacag tgaatattga agagttaaaa aaacaagccg aaacggaaat
    21001 cgccgacttt atcgcgcaaa aaatcgccga gctgaacaag aatacaggga aagaagtctc
    21061 tgaaattcgc ttcaccgcac gggaaaaaat gaccgggctt gaaagttatg atgtcaaaat
    21121 caaaataatg tgattttgtg aacatcaccc cgtgcgaggt gatgttccgc ttgttgctaa
    21181 tttagtgacc aatcgttggc gcttgtggaa ttaagcgtcg gtacaattcc tccggcaccg
    21241 ggctttgcca tactcccgca tacattgcgt aaccaatcac cgcaaacata atccccagaa
    21301 ccagtagtgt cattaaccag ccagacaacg caaaagcttt tttatttgcc gcaggttttt
    21361 gcagtgaaaa ggtcaatgtt gaggctaccg gacatgactc tacgcaagtc atacagccgg
    21421 tacattccac tgttcgtacc tgaattaatt tatcgaccgg gatccgtgat gggcaatttt
    21481 ttgcgcattt gccacagtcg atacaacttt cggcattgcg acgaatctta aacggcgata
    21541 atagcgaaac cacgcccatc agcgcgccat atgggcaaag ataacgacac caggcatggc
    21601 gaataaacag gctggcaatc agcaaaacgg tcacgctgat taatgtcgcg gtccccatat
    21661 gacgaaagaa atcgagcatt ttaacgtcca tcaccacgct gtagggcgac aacataaaat
    21721 agtgaatcgc ctgagcgggc atcaataacg cgatatagag aaaaaaactc aacagcaaat
    21781 acttcacgcc gcgcagagga atatccagcc agcggggaag gacacattgc cgaccaaaca
    21841 gtttgttacc gagatcgccg attaattcag aaagcgtacc aaccgggcat aaccatgagc
    21901 aaaaggcctt tttgagtaat agactgatga cgataaaagc gaccaataac agcatcgcgg
    21961 cggcgtggac ggacggtaac tgacctgtgg taaggctata tttcagattc atcagaccgg
    22021 caatcggtag ccagccttcg atacctcccg gtctggcgac aaatgtcgtg ctatttgccg
    22081 tttcgtaata gcgcacccaa taccagaacg tgatggcaat ataaatattc attgccaaca
    22141 gtaataattg cgtcgcttta cgccaggtcg tggcattgcg ccagttattc cacggtaatt
    22201 tgccgcccgt cgtgcctggc cgccgctgcc agcgggttct tttattctct gccatgattt
    22261 tgccagtccg ttaagttgca taccaaatgc cactattcta gttgttctta actggctgat
    22321 attgattcaa atcgcgttca ggtctttctt atgcaaccat gcttccagag cggcaacact
    22381 gcgtgtaatt tcttcgtgtg gaaggggggc agataatggc tgctgctcca gttgtgcgca
    22441 tagctggctg gcactgcaca ttcccagact cgagcaactg ctttttagct gatgtgcggc
    22501 acgctttatt ttctcgctat cctgactggc gcgggcaatg tcgatttcat cgagaagcgg
    22561 cagggcatgt tgtgtaaata ataccagcca ttcgtggatc ttctccgtcc ccattaactg
    22621 agcatcttca ttgagttgcg atacatccag cggttgatcg gtattggctt gcagttggag
    22681 atagtgcgcc agtaactgac cgagcacttc acgcggcacc ggtttaggga taatcccgcg
    22741 aaataatgaa ctggtacgct ggcgcaacgt ttcgtcgatg acatgagcgc taaagccaat
    22801 caaaaccagc gacggatatt gctgtaccag ttgtcgggca agggtaatgc cgtcgatatc
    22861 cggcagatca aaatccacca gtgcggcagc aaacggttcg ctattttgca gtgtctctaa
    22921 agcctgcgcg gcattgccaa cagcaacaac ctgcgcacca ctggtgttca gcatctcaac
    22981 ggtaattcgc tgggttagcg ggttatcttc aattaacagc aaacgtaaac cgtccagacg
    23041 caccgcctga ttggctgttt ttggctcggg tgcagtggca acacgtaacg gcaagcgtaa
    23101 acaaaaacag cttccaacct ccggcgtgct ggtggcgctc agttcgccgc ccatcgcctg
    23161 ggccagacgg ctactgatag tcagccccag cccggtgccg ccgcgtttgc cgcttacctg
    23221 cacaaatggc tggaagattt ctgccagttt cgcgggatca ataccgcagc cgctgtcttc
    23281 cacttcgacc agccattgct cgccatcagt gcggctacgt aaaacgatct gcccttcgtc
    23341 agtaaaacgt agggcgttgc tcaacaggtt ggttataacc tgacgaatac gtcgcggatc
    23401 gcccattaac gcgctcggta catcatcggc aattgccgtt gccaggcgaa tcgggcgacc
    23461 tttcacccgt ccgctcatta attgcagggt actttccagc agcgggcgcg gttcaaaggg
    23521 ttcatcgctg accgaaacat tcttgccgcc tgcttcgata gccgaataat cgagaatatc
    23581 gttcaggatg gtcagcaacg attcaccaga gtcagtaatt gcccgcaaat catcacgctg
    23641 ggcgttaagt gcggggttat ctgccagtag ctgtgcggtg ccgagaatac cgtacagcgg
    23701 tgtgcggatc tcatggctca tcgccgccag aaacgccgat tttgcctggc tggctttttc
    23761 tgcttccgcc cgtgcctggc ggtgttctat caccagttcc tgcaattcag ctgtacgcgc
    23821 tttgacctgc gccgccagct gttcgcggtg gcgattcagt gcatgaacat tgctgcgaaa
    23881 cgcatccatc agccgcccga tggtatccag ctcccgtacg ccagcggttt ccgggaaagg
    23941 ggagtcaata tcaccgtcca gcagccgttg cagcgcctgc gtttgttcgg caagtggacg
    24001 cgtgactgag cgataaacca cgcgccaaag gatcagaatc agtgcgcaaa gtgaaaccat
    24061 ccccagcaat aacaggctgt attgcccgcg tgcactggct ttttccagat gcgccagtcc
    24121 gtgctgatta cgcagctcaa tggtgtcgac cagctgactg acttcgctac taaactgcgc
    24181 gaactgggcg atgttatttt gtgcgagagt ttgtaggtga ttgctgattt cactgtcctg
    24241 ctgatacagc gccagcaaat cgctatattg gctaacggta gttaacgttg ttgcgacctg
    24301 cgcacgaaca cccggatctt caatgcgtat ttgccgacgt tgcagaattt tcaccgcatt
    24361 attgagctgc ttttccagcg ttggtgcatt tttctggatc tgctccagcc ccagattcat
    24421 caccatttgc tgcacccgca gagcgctaag gcgcagttca ttcatctggt taacatactc
    24481 aagatcgata tcaatcagcc gatcgagtgc actttcagca gcctgacgct gatcttgttc
    24541 gatcaaatcg taaatcccgg cctgggtcgc tccagcggaa gttgtcgcat tattcgcctg
    24601 accttgcgcc aggcgtgcga tctcatcggc ggcagcgact atctgctgac tgagttgccg
    24661 ttgttgctgg cgtagttgca gacgccgccc caccagttcc ccttgctgac gtaatgaacg
    24721 ggagatctcc tgctcctgtt gttcaatagc ggtggtatca aaaccttgtt cccgtaacgc
    24781 ttgcagcaac gcattaatct tcaggctttg tgcggtgagc attcgcccct gcgcctgcca
    24841 catcttttcg ttatcggcac tggtcaggtt ctgcgcggcg aaaagttccc aggcgctggc
    24901 ttcgctcaac tggcgcgcca tattcatggt aggaatcaat gcctgagtgt tgtctttttc
    24961 cacctggctg ataaagcgca ggttgtacca tcccaccagg gtactggtca gggttaacag
    25021 cgccatcagg gcaaagccca tccagagtct tcgggtcagg gttaaattca cggtcggtgc
    25081 acttaaggtg aataagttgt atgtttaaaa tctcttttac tatcaatgaa ttagtattgg
    25141 caggtcatta ttggtcaaaa taaaatcatt tgtcgatttc aattttgtcc cattcccgtc
    25201 cacggctgtc tctataccgc gccgccattg aatctgattt atgcccgaga agacgttgag
    25261 caaatttatc gccaatctgg ttccggtata gcctcgctga caggctacgc agttcatgga
    25321 atgttggcgg gtttccatca aatgagagtc cagatgcatt tctcgccttt gtaaaatact
    25381 ttgatactgt tttcggggaa agaggatcgt aatgctttga tgcgattata gtttcactgc
    25441 tgctggcctc cctgcatttc tgtagtgtat cagccaatga gatattgagc gcgtcaatcg
    25501 ttagcgttag cggaatggcg agtttagccc ctgttttact ctgttcaatg tgaagatggt
    25561 tgtcgtttat gtctgaccat ttcattctgc acaaatcgcc gactctctgc cctgtaacga
    25621 cggccaaatc catcgccagc cttagccaga tagggagagg ttcggctgca tggtaaatct
    25681 cgacatactc attagctgtc agccttgagc gccttacttc tgactttgct gtacgggttg
    25741 ctgttaccgg attcgttgcc acatgcccct cggctattgc ttcacgaaaa acgtcaacaa
    25801 gggttgacct gattaatttt gcggaagctg ctttaccttc tgctacgtag gtgtttagca
    25861 ttgctgccac ttctttcgtt gatatgtcag tgagcggttt gtccggcaat tttcttcgga
    25921 ttgccctgat tttgctggcg tagtcgagta gagttttcgg cctgatcccc ctttcggtga
    25981 ggattgtttc atatcggtca agccacacat gaagagtgat tgcgtcaccg cctttaattc
    26041 tgtctattag tgatttgcgt ccgctgtctg agagtaactc aatattggcc tgtattgctt
    26101 cagtgattgc tatcctcctg tctcggccta aaccaaactc tttacccgtc cttgggtccc
    26161 tgtagcagta atatccattg tttcttatat aaaggttagg gggtaaatcc cggcgctcat
    26221 gacttcgcct tcttcccatt tctgatcctc ttcaaaaggc tacctgttac tggtcgattt
    26281 aagtcaacct ttaccgctga ttcgtggaac agatactctc ttccatcctt aaccggagga
    26341 gggaatatcc tgcattcgcg cacccatcga cgaactgttt caag
//
LOCUS       DAZUDJ010000065        26329 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.065, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000065 DAZUDJ010000000
VERSION     DAZUDJ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26329
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.065"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..138
                     /locus_tag="ACHY1N_003682"
     CDS             <1..138
                     /locus_tag="ACHY1N_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 family protein"
                     /protein_id="HFS4045906.1"
                     /translation="YRWHGSAEAYTGREVQDIPGVLAVFAERRKDSFGPYVRLMSVTL
                     N"
     gene            212..580
                     /gene="cbeA"
                     /locus_tag="ACHY1N_003683"
     CDS             212..580
                     /gene="cbeA"
                     /locus_tag="ACHY1N_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system cytoskeleton
                     bundling-enhancing antitoxin CbeA"
                     /protein_id="HFS4045907.1"
                     /translation="MSDTLPGTTLPDDNHDRPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGLFSDADAYHLDQAFPLLMKQLELMLTSGELNPRHQHTVTLYAKGLTCKAD
                     TLSSCGYVYLAVYPTPEMKN"
     gene            669..1042
                     /gene="cbtA"
                     /locus_tag="ACHY1N_003684"
                     /pseudo
     CDS             669..1042
                     /gene="cbtA"
                     /locus_tag="ACHY1N_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system
                     cytoskeleton-binding toxin CbtA"
     gene            1039..1233
                     /gene="yeeW"
                     /locus_tag="ACHY1N_003685"
     CDS             1039..1233
                     /gene="yeeW"
                     /locus_tag="ACHY1N_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5983 family protein"
                     /protein_id="HFS4045908.1"
                     /translation="MMTLEADSVNVQALDMGHIVVDIDGVNITELINKAAEKGYSLRV
                     VDDRDSTETPATYASPHQLL"
     gene            1279..1359
                     /locus_tag="ACHY1N_003686"
                     /pseudo
     CDS             1279..1359
                     /locus_tag="ACHY1N_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1648..1794)
                     /locus_tag="ACHY1N_003687"
                     /pseudo
     CDS             complement(1648..1794)
                     /locus_tag="ACHY1N_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080164.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            1848..2030
                     /locus_tag="ACHY1N_003688"
     CDS             1848..2030
                     /locus_tag="ACHY1N_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006576 - biogenic amine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HFS4045909.1"
                     /translation="MNHPVIGVVTKADLASMEQISLVKSWLREAGAHNVLVTSAVNNN
                     GVTELFALLHTEEGCC"
     gene            complement(2131..2460)
                     /gene="tmaR"
                     /locus_tag="ACHY1N_003689"
     CDS             complement(2131..2460)
                     /gene="tmaR"
                     /locus_tag="ACHY1N_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HFS4045910.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGE
                     MKNGEAK"
     gene            complement(2632..3690)
                     /gene="yeeA"
                     /locus_tag="ACHY1N_003690"
     CDS             complement(2632..3690)
                     /gene="yeeA"
                     /locus_tag="ACHY1N_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFS4045911.1"
                     /translation="MRADKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPE
                     STWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGSILGLIALQLELISLPLMLVWCA
                     AAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEIDTALWRSGDVILGSLLAMLFTG
                     IWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERPRLESHLQKLLTDAVKMRGLIA
                     PASKETRIPKSIYEGIQTINRNLVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQ
                     QILLSLVHALYEGNPQPVFANTEKLNDAVEELRQLLNNHHDLKVVETPIYGYVWLNME
                     TAHQLELLSNLICRALRK"
     gene            complement(3888..4361)
                     /gene="sbmC"
                     /locus_tag="ACHY1N_003691"
     CDS             complement(3888..4361)
                     /gene="sbmC"
                     /locus_tag="ACHY1N_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HFS4045912.1"
                     /translation="MNYEIKQEDKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVP
                     KEWVAIYYDNPDETPAEKLRCGTVVTVPGYFTLPENSEGVILTEISGGQYAVAVARVV
                     GDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH"
     gene            complement(4480..5646)
                     /gene="dacD"
                     /locus_tag="ACHY1N_003692"
     CDS             complement(4480..5646)
                     /gene="dacD"
                     /locus_tag="ACHY1N_003692"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
                     /protein_id="HFS4045913.1"
                     /translation="MKRRLIIAASLFVFNLSSGFAAENIPFSPQPPEIHAGSWVLMDY
                     TTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDNPVF
                     VGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEKLH
                     LKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRN
                     GLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQHRLIAVIMGADSAKGREEEARKLLR
                     WGQQNFTTVQILHRGKKVGTERIWYGDKENIDLGTEQEFWMVLPKAEIPHIKAKYTLD
                     GKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSRLSDYFHHKA"
     gene            5855..7282
                     /gene="sbcB"
                     /locus_tag="ACHY1N_003693"
     CDS             5855..7282
                     /gene="sbcB"
                     /locus_tag="ACHY1N_003693"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008310 - single-stranded DNA 3'-5' DNA
                     exonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HFS4045914.1"
                     /translation="MMNDGKQQSTFLFHDYETFGTHPALDRPAQFAAIRTDSEFNVIG
                     EPEVFYCKPADDYLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGY
                     NNVRFDDEVTRNVFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDDG
                     LPSFRLEHLTKANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFTHRNKHKLM
                     ALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVIMVDLAGDISPLLELDS
                     DTLRERLYTAKTDLGDNAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDNL
                     KILRENPQVREKVVAIFAEAEPFTPSDNVDAQLYNGFFSDADRAAMKIVLETEPRNLP
                     ALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQVFTPEFLQGYADELQML
                     AQQYADNKEKVALLKALWQYAEEIV"
     gene            complement(7325..7552)
                     /gene="tsuB"
                     /locus_tag="ACHY1N_003694"
     CDS             complement(7325..7552)
                     /gene="tsuB"
                     /locus_tag="ACHY1N_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate utilization sulfurtransferase
                     TsuB/YeeD"
                     /protein_id="HFS4045915.1"
                     /translation="MAIKKLDVVTQVCPFPLIEAKAALAGMASGDELVIEFDCTQATE
                     AIPQWAAEEGHAITDYQQIGDAAWSITVQKA"
     gene            complement(7566..8624)
                     /gene="tsuA"
                     /locus_tag="ACHY1N_003695"
     CDS             complement(7566..8624)
                     /gene="tsuA"
                     /locus_tag="ACHY1N_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate utilization transporter TsuA/YeeE"
                     /protein_id="HFS4045916.1"
                     /translation="MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYLAKNNRMFYA
                     LLIAISVQSVGVFALIQAGLLTYEAGAFPWLGTVIGGYIFGLGIVLAGGCATGTWYRA
                     GEGLIGSWIALFTYMVMSAVMRSPHASGLNQTLQHYSTEHNSIAETFNLSVWPLVAVL
                     LVITLWVVMKELKKPKLKVATLPPRRTGIAHILFEKRWHPFVTAVLIGLIALLAWPLS
                     EATGRMFGLGITSPTANILQFLVAGDVKYINWGVFLVLGIFVGSFIAAKASREFRVRA
                     ADAQTTLRSGLGGVLMGFGASIAGGCSIGNGLVMTAMMTWQGWIGLVFMILGVWTASW
                     LVYVRPQRKARLATAAAN"
     gene            complement(8803..10161)
                     /gene="plaP"
                     /locus_tag="ACHY1N_003696"
     CDS             complement(8803..10161)
                     /gene="plaP"
                     /locus_tag="ACHY1N_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HFS4045917.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYED
                     VA"
     gene            complement(10151..10213)
                     /gene="yoeI"
                     /locus_tag="ACHY1N_003697"
     CDS             complement(10151..10213)
                     /gene="yoeI"
                     /locus_tag="ACHY1N_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HFS4045918.1"
                     /translation="MGQFFAYATVITVKENDHVA"
     gene            complement(10428..11357)
                     /gene="yeeY"
                     /locus_tag="ACHY1N_003698"
     CDS             complement(10428..11357)
                     /gene="yeeY"
                     /locus_tag="ACHY1N_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4045919.1"
                     /translation="MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESD
                     LNIQLLDRSGHRAKFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIEAFYQHHSVTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFG
                     FSRLGDLEQVFAVAPHHPLALEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQ
                     TAGLASGWWRDEILANSAIAGVYAKSDDGKSAI"
     gene            complement(11403..12227)
                     /gene="yeeZ"
                     /locus_tag="ACHY1N_003699"
     CDS             complement(11403..12227)
                     /gene="yeeZ"
                     /locus_tag="ACHY1N_003699"
                     /EC_number="1.1.1.290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4045920.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLSARGWQVTGSKTTQDGVEAARMSG
                     IDSYLLRMEPELVCDSDDLDALMDADALVITLPARRSGPGDEFYLQAVQELVDSALAH
                     RIPRIIFTSSTSVYGDAQGTVKETTPRNPVTNSGRVLEELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGEHGVNLVHLEDVIGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMARLLGLEPPQFRNSLDSGKGKIIDGSRICNELGFEYQYPDPLVMPLE"
     gene            complement(12310..12564)
                     /gene="yoeB"
                     /locus_tag="ACHY1N_003700"
     CDS             complement(12310..12564)
                     /gene="yoeB"
                     /locus_tag="ACHY1N_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YoeB"
                     /protein_id="HFS4045921.1"
                     /translation="MKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGK
                     PEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAACRYHY"
     gene            complement(12561..12812)
                     /gene="yefM"
                     /locus_tag="ACHY1N_003701"
     CDS             complement(12561..12812)
                     /gene="yefM"
                     /locus_tag="ACHY1N_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416521.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoeB-YefM toxin-antitoxin system antitoxin YefM"
                     /protein_id="HFS4045922.1"
                     /translation="MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEE
                     YNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKDIIE"
     gene            13095..13145
                     /gene="hisL"
                     /locus_tag="ACHY1N_003702"
     CDS             13095..13145
                     /gene="hisL"
                     /locus_tag="ACHY1N_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HFS4045923.1"
                     /translation="MIRVQFKHHHHHHHPD"
     misc_feature    13121..13244
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00514"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="His leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00514"
     gene            13291..14190
                     /gene="hisG"
                     /locus_tag="ACHY1N_003703"
     CDS             13291..14190
                     /gene="hisG"
                     /locus_tag="ACHY1N_003703"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HFS4045924.1"
                     /translation="MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFG
                     GCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     gene            14196..15500
                     /gene="hisD"
                     /locus_tag="ACHY1N_003704"
     CDS             14196..15500
                     /gene="hisD"
                     /locus_tag="ACHY1N_003704"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HFS4045925.1"
                     /translation="MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVK
                     ARGDEALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNVETFHTAQ
                     KLPPIDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLC
                     SPPPIADEILYAAQLCGVQDVFNIGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDTD
                     MAHQVAEAVERQLAELPRAETARQALSASRLIVTKDLAQCVEISNQYGPEHLIIQTRN
                     ARELVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA"
     gene            15497..16567
                     /gene="hisC"
                     /locus_tag="ACHY1N_003705"
     CDS             15497..16567
                     /gene="hisC"
                     /locus_tag="ACHY1N_003705"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFS4045926.1"
                     /translation="MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVE
                     FQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDS
                     ILYCPPTYGMYSVSAETIGVECRTVPTLDNWQLDLQGISDKLDGVKVVYVCSPNNPTG
                     QLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFAL
                     AGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAER
                     EYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCL
                     RITVGTREESQRVIDALRAEQV"
     gene            16567..17634
                     /gene="hisB"
                     /locus_tag="ACHY1N_003706"
     CDS             16567..17634
                     /gene="hisB"
                     /locus_tag="ACHY1N_003706"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HFS4045927.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLKLQ
                     KAGYKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECD
                     CRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGINGLRYDREILNWPMIGE
                     QLTKRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEI
                     NVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGICRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            17634..18224
                     /gene="hisH"
                     /locus_tag="ACHY1N_003707"
     CDS             17634..18224
                     /gene="hisH"
                     /locus_tag="ACHY1N_003707"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HFS4045928.1"
                     /translation="MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFL
                     PGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDED
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM"
     gene            18224..18961
                     /gene="hisA"
                     /locus_tag="ACHY1N_003708"
     CDS             18224..18961
                     /gene="hisA"
                     /locus_tag="ACHY1N_003708"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HFS4045929.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAE
                     VLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVG
                     STAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDINDVAALRGTG
                     VRGVIVGRALLEGKFTVKEAIACWQNV"
     gene            18943..19719
                     /gene="hisF"
                     /locus_tag="ACHY1N_003709"
     CDS             18943..19719
                     /gene="hisF"
                     /locus_tag="ACHY1N_003709"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HFS4045930.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGA
                     DELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETL
                     DWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC"
     gene            19713..20324
                     /gene="hisIE"
                     /locus_tag="ACHY1N_003710"
     CDS             19713..20324
                     /gene="hisIE"
                     /locus_tag="ACHY1N_003710"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HFS4045931.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
     gene            complement(20420..21397)
                     /gene="wzzB"
                     /locus_tag="ACHY1N_003711"
     CDS             complement(20420..21397)
                     /gene="wzzB"
                     /locus_tag="ACHY1N_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310855.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen chain length determinant protein
                     WzzB"
                     /protein_id="HFS4045932.1"
                     /translation="MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIAL
                     AIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGSAVPKVSDIQASLIGRYSTA
                     FSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETPEGAQKQLAKYIQQVDDQVN
                     EELGKDLKDNIAQRMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQ
                     QTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDIESLKVDDLDIHA
                     YLYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNYNAK"
     gene            complement(21544..22710)
                     /gene="ugd"
                     /locus_tag="ACHY1N_003712"
     CDS             complement(21544..22710)
                     /gene="ugd"
                     /locus_tag="ACHY1N_003712"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003979 - UDP-glucose 6-dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HFS4045933.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRYADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLAIFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            complement(22958..24364)
                     /gene="gndA"
                     /locus_tag="ACHY1N_003713"
     CDS             complement(22958..24364)
                     /gene="gndA"
                     /locus_tag="ACHY1N_003713"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFS4045934.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            complement(24470..25498)
                     /gene="galE"
                     /locus_tag="ACHY1N_003714"
     CDS             complement(24470..25498)
                     /gene="galE"
                     /locus_tag="ACHY1N_003714"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFS4045935.1"
                     /translation="MAILVTGGAGYIGSHTVLMLLKEQYEVIVLDNFHNSSVESLHRV
                     KEITGSDICIINGDIRDRVILKSIFTENSITDVIHFAGLKSVSDSIQFPTEYYDNNVY
                     GTLVLIEEMISNNIKNLIFSSSATVYGTPEKIPVKETFPVGGTTNPYGTSKLMVENIL
                     HDVSLAYPFFRTTILRYFNPVGAHPSGKIGEDPNGIPNNLMPYICSVASGKYKQLSIY
                     GNDYETKDGTGVRDFIHVMDLANGHIAALKHRDEGSNYKVYNLGTGHGYSVLELLAAF
                     QRITSVNIPYVLVERRAGDIAECWSDPSKAYLELGWKACLGLDEMVRDAWNWQQSNPD
                     GYKFSEKN"
     gene            complement(25577..>26329)
                     /locus_tag="ACHY1N_003715"
     CDS             complement(25577..>26329)
                     /locus_tag="ACHY1N_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFS4045936.1"
                     /translation="NKDKDSFKKIVLRKIQGFLYKMTLPFATKVLFLNNDDYHDLVVK
                     NNIKIKDYKVIGGIGVNLNEFSYHPPICGEIHFGMVARLLREKGVCEFVEAAKIIKKK
                     YPMVRFSIAGDFDDNPGGIDAAQIVNWKAEGYVEFLGPCSYIKEYLSDISVFVLPSYR
                     EGVPKSTQEAMAIGRAIITTDVPGCRETVIDGYNGYLVPPWDTQKLALVMETFIHERE
                     LIVTMGLNSRRFALSKFNESESANSLVNIITA"
BASE COUNT         6940 a         6664 c         6264 g         6461 t
ORIGIN      
        1 taccgctggc acggcagtgc tgaagcgtat accggtcgtg aagtgcagga tattcccggt
       61 gtgctggccg tgtttgctga acgccgtaag gacagttttg gtccgtatgt ccggctgatg
      121 agcgtcaccc tgaactgagt gggaattctg atgagcagaa ttatcgccac taccggacca
      181 ttcttagccg attttctgta aggattttat cgtgtcagac acactccccg ggacaacact
      241 tcccgacgac aatcacgacc gcccctggtg ggggctgccc tgcaccgtga cgccctgttt
      301 cggggcacgt ctggtgcagg agggtaaccg gttgcattac cttgccgacc gcgccggtat
      361 cagaggcctg ttcagcgatg cagatgcgta ccacctggac caggcctttc cgctgctgat
      421 gaaacaactg gaactcatgc tcaccagcgg tgaactgaat ccccgccatc agcataccgt
      481 cacgctgtat gcaaaagggc tgacctgcaa agccgatacc ctcagcagtt gtggttacgt
      541 ttatctggct gtttatccga cgcccgaaat gaaaaattaa ctctccagaa tagccttctg
      601 ctacggcctg gtgttttcac cacgccactt ttccattttt atatctgcat atcaggaaaa
      661 tcttcagtat gaaaacatta cctgtattac ccgggcaggc gaccagttct cacccgtctc
      721 ctgttgaaat ctggcagata ctgctgtccc gactgctgga ccagcactat ggcctcacac
      781 tgaatgacac accttttgcc gatgaacgtg tgattgagca gcatattgag gcaggcattt
      841 cactgtgtga tgcggtgaac tttctcgtgg aaaaatacgc gctggtgcta ccgaccagcc
      901 gggattcagc gcctgtaccc gctctcagtt aataaacagc atcgatatcc tccgggctcg
      961 cagggcgacc ggcctgatga cccgcgacaa ttacagaacg gtaaataaca ttaccctggg
     1021 taagtatccg gaggcgaaat gatgacactg gaagccgaca gcgttaacgt acaggcgctg
     1081 gatatggggc acattgtcgt tgacattgat ggtgttaata tcactgaact gattaataag
     1141 gccgctgaaa aaggttattc actccgcgtg gtggatgacc gtgactctac cgaaacaccg
     1201 gcaacttatg ccagccctca ccagttgctg taagacaatg cagtgatgca gggtatagtg
     1261 ccattaacca cagaaacagc actgttgtcc tgtattaagc aggcaagaga agatgtcctt
     1321 accctgcgcc atctgcagct tctgcaccag aaccggtgaa tctcactcaa caggcttcat
     1381 ttcccctgac gccagcctga atacagctgg cgttttcatt tataaacaga aaggaaaacc
     1441 gataataatg gaatggacgc cccgaccatg aagcaacggt aggatattac tgataaacct
     1501 tccagtggag gtgcgttatg gccgttttaa cgattagcat tgacctgaca aaaaatgaat
     1561 tccaaatcca cggtctgggt aggaacagaa aaatctaagc tcagaaaacg gattaaagta
     1621 agcgtcaacg gagcaccgta ttgacgctta tttattggtg agaactacgt tccatggcag
     1681 gagttcgtca acacggttgg agggccattc cggcagtatg ctcagaatat ggcgcagata
     1741 cgcttccgga tcgataccgt tcagacggca ggtgcctgct tttccggcaa caagcaggaa
     1801 tctcagcgct gaagcaggaa ttagaggtaa aaacgcccta ccgggccatg aatcacccgg
     1861 tcattggagt agtaaccaaa gcagatttag ccagcatgga acaaatatct ttggtgaaaa
     1921 gttggttacg ggaagctgga gcgcacaacg tgttagtaac cagtgcagtt aataacaatg
     1981 gagttacaga actttttgcc ttgctgcata cagaagaagg ctgttgttaa tttcgattgg
     2041 ttctcagatg agaatgatga cggtgataca cagataagaa tcaatgagca atgagggttg
     2101 ccgggcaacc ctcattgaat aaaacgggaa ttacttcgct tcgccgtttt tcatttcgcc
     2161 catagctttc agctttttgg agatatcgcg gcgttctttg gagagctcgg catttttgat
     2221 gatgtaatcg tcaacgcgat cttcatagtc acctttcatg ctggcgatga tgccctggat
     2281 tgcttcaacg ctcatccctg gcttgatgta atcgctcagg ttgtccagca acaggacgcg
     2341 cttctggttg tcacggatct ttttctcaac gtcctgaatt tcacgttgca gtttgttctt
     2401 acgacggaac agacgaacaa attccagtac gtcctggaat gaaggcttgg tagtttccat
     2461 ttttataccc ctgataatgt gagagtcgga ttcgtttaag caaccgctat tcgttagggc
     2521 caacattact catagctgcc gcagatgaca atgcttttat cccttttcac tatcataccc
     2581 tttatccttg ctgaatcgaa gcagcagcaa gatgattctg aagttcagga attatttgcg
     2641 caaggcccgg caaatcagat tcgatagcaa ctcaagctga tgtgccgttt ccatgttcag
     2701 ccacacataa ccatagattg gtgtttccac aaccttcagg tcatggtggt tattcagcaa
     2761 ctgacgcagc tcttccacag catcgttcaa tttttccgta ttggcaaaaa ccggctgcgg
     2821 attaccttcg tacagcgcat gaacaaggct cagcagtatt tgctgcatca tatgctgggt
     2881 atcacgaagt ttttgcgcgt tcaataacac gaaatggctg gggcgcgtgg cccagtacgc
     2941 attgatttgc aactccagca tacaaaccag attgcggtta atggtctgga taccttcata
     3001 tatcgatttt ggaatacggg tttctttgct ggcgggcgca atcagcccac gcattttcac
     3061 ggcatcggtc aagagttttt gtagatggct ttccagacgt gggcgttcga gtaagttcgg
     3121 tgagaatgca gattgataga cccgattata ctcggtcaga cttttcgcca gttgaatgcg
     3181 ccagtggatg aacgcccgtt gtggccagat accggtaaac aacattgcca gtaaagagcc
     3241 gaggatcaca tcgccgcttc gccataacgc cgtatcaatt tcacctgtcg gggaaccaac
     3301 aacaattgcc agcgtcaccc caatcaataa tccttgatac ggtttcttgc ccagcgccag
     3361 ccaaccgcaa agaaacatcg ccgccgcgca ccagactaac atcagcggta acgaaattaa
     3421 ctccagttgc agagcgataa gacccaaaat cgaacccaac accgtaccgc caatacgttc
     3481 gaaggcgcga gggacaacgt taccccagaa cgagattggc cccataatca ccaccatggt
     3541 gaccagcggc caggtgcttt ccgggatagt aaacaggcgg ataatgagaa aagtgagcag
     3601 gaatgccagc gcgacccgag taccatgcac aatgcggtaa tggcggtata cccggatttc
     3661 aaacgggctt aatgacttat cggcacgcac gcagaaactc cgtaatgaag attaaaagcg
     3721 ctcataactc atctgtcggc cagaaggcgc gcctctgaat tatccgacgg acataccggg
     3781 aacagtgtaa tttcccggca ggagcgaaaa atttgaaagg cgcatcttac tcttttcgct
     3841 ttcaaaaaaa gagtggtcat cgcgttaaca caccgccctg agatgaatta gtgatgtttt
     3901 ggctgcaccg caacatacat ttcgatatcc cagtacccat cttccgcgcc attgttcaag
     3961 taaacctcga agcagggctt tggtaacatt tcataagcac tgtcctgcaa gaggctatta
     4021 aagaactgat accagggttt agcaaaatca tcaccgacta cacgagctac cgccaccgca
     4081 tactgaccac ctgaaatttc tgtcagaatg acgccctcac tgttttcggg aagcgtaaag
     4141 taacccggca ccgtcacgac ggtgccgcag cgtaattttt cggcgggtgt ttcatctgga
     4201 ttgtcgtaat agatagcaac ccactccttc ggcacaatat ttttactatc tacccacatc
     4261 atcaactgct caaaaccttt ctttaccgtc tgttcccagg ggccaacgag atggaaacct
     4321 gcaacggtac gtttatcttc ctgcttaatc tcgtagttca tgacgcctcc attaatactg
     4381 tttttatata cagtatagtt gcaatattaa aaccacaagg aatgagtgtt gattatgcga
     4441 gcagactcgc actcctgcca gtctgctgca aaagaaaggt caggccttat ggtggaaata
     4501 atcactcagg cgagaaaaca tgctgccttc cccgacagat tccagggtaa ccagcggcca
     4561 gtgcgccacc tgtttatcac ggtcgtaaag ttcaatttcc cctacccgct gatgggcgct
     4621 aattggcgcg gtgagttctt taccatcaag ggtatatttg gctttgatat gtggaatttc
     4681 ggctttcggt agcaccatcc agaactcttg ttccgttccc aggtcgatat tttctttatc
     4741 gccataccag atgcgttccg ttccgacctt tttcccacgg tgcaaaattt gcaccgtagt
     4801 aaagttttgt tgcccccaac gcagtaattt tcttgcctct tcctcacgac cttttgcact
     4861 gtcagccccc attatcactg caatgagacg atgctgccca tctacagccg aagcaatgag
     4921 attaaacccg gcaccagaag tatgacccgt tttcaggccg tcaacattca tggttttatc
     4981 ccacaataat ccgttacggt tttgctgggt gataccgttc caggtgagac ttttctcact
     5041 gtacatatga taaaactcgg gctcgccgtg gatgatagca cgagaaagca cagctaaatc
     5101 ataagccgag ctatgctggc caggtgcatc cagaccatgc actgtttcaa aatgcgtatc
     5161 cttgagatgc agtttctcgg catagttgtt catcatttca acaaactgcc gttgcccacc
     5221 ggcaatatag tcagccagag caacacaagc gtcatttccg gaatccacaa ttaaaccacg
     5281 gcttaaatca cgtaccgata cgcgatcgcc ctctttcaaa aacatcagtg aagaaccgac
     5341 aaacaccgga ttatctttcg cccacgcatc gcgccccacg gtgacaatat cgtctggcgt
     5401 aatgcgatga ctatcgatag cgcgatccac gacataaccc gtcatcagct ttgtcaggct
     5461 ggcgggattg cgctgttgat gctcattacc cgcggtgagg atctgaccgg tggtgtaatc
     5521 catcaatacc caggacccgg catgaatctc tggaggctga ggtgaaaaag gaatgttttc
     5581 cgccgcaaaa ccagacgata agttaaaaac gaacaaagaa gcagcaataa taagacggcg
     5641 tttcaacagc aaaccctcag gagtttcaaa tagctgttct ttttacggaa atacttatga
     5701 actggctgga ataaagtgca agaaaatgtg actaccctct catttttatc tgacatgatc
     5761 tgttgccact cgctgccaaa ttgtggcgct aaagctgatt agcacggtga tatttgatac
     5821 tctggcagac agcagaaata acggatttaa cctaatgatg aatgacggta agcaacaatc
     5881 tacctttttg tttcacgatt acgaaacctt tggcacgcac cccgcgttag atcgccctgc
     5941 acagttcgca gccattcgca ccgatagcga attcaatgtc atcggcgaac ccgaagtctt
     6001 ttactgcaag cccgcggatg actatttacc ccagcctgga gcagtattaa ttaccggtat
     6061 taccccgcag gaagcacggg cgaaaggaga aaacgaagcc gcgtttgccg cccgtattca
     6121 ctcgcttttt accgtaccga agacctgtat tctgggctac aacaatgtgc gtttcgacga
     6181 cgaagtcaca cgcaacgttt tttatcgtaa tttctacgat ccttacgcct ggagctggca
     6241 gcatgataac tcgcgctggg atttgttgga tgttatgcgt gcctgttatg ccctgcgccc
     6301 ggaaggaata aactggcctg aaaatgatga cggtctaccg agctttcgcc ttgagcattt
     6361 aaccaaagcg aatggtattg aacatagcaa cgcccacgat gcgatggctg atgtgtacgc
     6421 cactattgcg atggcaaagc tggtaaaaac gcgtcagcca cgcctgtttg attatctctt
     6481 tacccatcgt aataaacaca aactgatggc gttgattgat gttccgcaga tgaaacccct
     6541 ggtgcacgtt tccggaatgt ttggagcatg gcgcggcaat accagctggg tggcaccgct
     6601 ggcgtggcat cctgaaaatc gcaatgccgt aattatggtg gatttggcag gagacatttc
     6661 gccattactg gaactggata gcgacacatt gcgcgagcgt ttatataccg caaaaaccga
     6721 tcttggcgat aacgccgccg ttccggttaa gctggtgcac atcaataaat gtccggtgct
     6781 ggcccaggcg aatacgctac gcccggaaga tgccgaccga ctgggaatta atcgtcagca
     6841 ttgcctcgat aacctgaaaa ttctgcgtga aaatccgcaa gtgcgtgaaa aagtggtggc
     6901 gatattcgcg gaagccgaac cgtttacgcc ttcagataac gtggatgcac agctttataa
     6961 cggctttttc agtgacgccg atcgcgcagc aatgaaaatt gtgctggaaa ccgagccgcg
     7021 taatttaccg gcactggata tcacttttgt tgataaacga attgaaaaac tgttgttcaa
     7081 ttatcgggca cgcaacttcc cggggacgct ggattatgcc gagcagcaac gctggctgga
     7141 gcaccgccgc caggtcttca cgcccgagtt tttacaaggt tatgcagatg aattgcagat
     7201 gctggcacaa caatatgccg ataacaaaga aaaagtggcg ctgttaaaag cgctttggca
     7261 gtacgcggaa gagatcgtct agtttgaagc ctccgccgct gatacggcgg aggacaatgt
     7321 tgggtcaggc tttttgaacg gtgatgctcc acgcagcatc gccaatctgc tgataatcgg
     7381 tgatggcatg tccttcttct gccgcccatt gtgggattgc ttctgttgcc tgggtgcaat
     7441 caaactcaat taccaactca tcgccgctgg ccattcctgc cagtgctgct tttgcttcta
     7501 tgagtggaaa cggacagacc tgcgtcacca catccagctt tttaatcgcc atctttacac
     7561 cttacttaat ttgccgcagc agttgccagt cgcgccttac gctgcggtcg aacatacaca
     7621 agccaggacg cagtccagac tccgagaatc ataaatacaa ggccaatcca gccctgccag
     7681 gtcatcattg cagtcataac cagtccatta ccgatagagc aaccacctgc aatactggca
     7741 ccgaagccca tcagtacacc acctaacccg ctacgtaatg ttgtttgtgc atcagctgcg
     7801 cgaacgcgga actcacggct cgctttggct gcaataaatg accccacgaa gatccctaac
     7861 accaggaaaa cgccccagtt aatgtatttc acgtcacccg cgaccagaaa ttgcagaata
     7921 ttggccgttg gggaagtgat tcctaaccca aacatgcgtc cggttgcttc actcaggggc
     7981 caggctaaaa gcgcaatcaa accgatgagt acagcagtga caaagggatg ccagcgtttt
     8041 tcaaacagaa tatgagcgat cccggttcgg cgcggcggta aggtcgcgac tttgagtttt
     8101 ggcttcttca actctttcat caccacccag agcgttatca ccagcaaaac ggcaaccaac
     8161 ggccacacag acaaattaaa agtctcagca atagagttat gttcagtact gtagtgctgc
     8221 aaggtttgat ttaaaccact ggcatgtgga gaacgcatca ccgcactcat caccatataa
     8281 gtgaaaagcg cgatccaact gccgatcaat ccctcacccg cgcgatacca ggtcccggtg
     8341 gcacatccac ccgccagaac aattcccagc ccaaagatat acccacctat aacagtacca
     8401 agccacggga acgccccggc ttcgtaagtc agtaggcccg cctgaattaa cgcaaaaacc
     8461 cccacacttt gtaccgaaat tgcaatcagc aaggcgtaaa acatgcgatt atttttcgcg
     8521 agatacatat cgcgaaaacc acctgtcagg caaaaacgcc cacgctgcat gacaaatccc
     8581 agcagagcac cacaaattag cccgcttaat atcattgaaa acataaatta attaaccaga
     8641 tgaatgttaa tagggaaatt attcatgact ggtggaatgc agaccaataa ccaaattctc
     8701 taaattagaa caaatggtta ttaatgagga tgtcgataaa aaagaataaa aaaaccggag
     8761 ccaaatattc attcgactcc ggtttattat tacaaaagat gattacgcta cgtcttcgta
     8821 ctgcggaacc gggttacgga aactcttggt gacgcaagcc aggtaaatca gaccgatagc
     8881 cgcccagatc agacccagaa ccattgagct ttcttccagg ttaacccaca gcgcaccaac
     8941 ggtcagcgca ccacacatcg gcaggaacag atactggaag tgatctttca gcgtcttatt
     9001 acgcttctca cggatccaga actgcgagat gaccgacagg ttaacgaagg tgaacgccac
     9061 caacgcacca aagttaatca gcgctgtagc cattaccagg tcgaagttga ttgccagcag
     9121 ggcaatcgcg ccaaccagga tgatgttcat cgccggagta cgccatttcg ggtgtacata
     9181 accgaagaag cttttcggga atacgccgtc acgacccatt acgtacatca gacgcgctac
     9241 gcctgcatgc gccgccatac cggacgccag tacggtaatg gtggagaaga tcagcgcgcc
     9301 aacctggaac gctttacccg caacgtacag catgatttca ggctgtgacg catccggatc
     9361 tttaaagcga gagatatccg ggaagtacag ctgcaggaag taagttgcaa agatgaagat
     9421 catgccgcca atcagcgcgg tcaggaaaat cgcacgcggg atcacgcgct ctgcatcttt
     9481 ggtttcttcc gacaggttgc tgatgccgtc aaagccggta aaggagaagc acaggattgt
     9541 cgccccggta atcatcggga taacatgcgc atcgccagac cagaacggac gagtgctcgc
     9601 cagcgtacca gcgccttcac cttcaaatac gccataaaca accatgccca gaatcaccgc
     9661 gatcagcacc acctgcaaca cgacgattac agtgttgaag ttcgctacgg atttcagact
     9721 acgcaggtta aaggcggtca tgaaggccac caacgccacc acaaacatcc acgatgggat
     9781 ggaaggcacc agagcttcaa aatagatttt cgccagcaga atgttgatca tcggcgcgaa
     9841 cagatagtcg agcagagaag accaacccac cataaagccg acagtcgggc taatggattt
     9901 ctgggcgtaa gtgtatgcag agccagcaga aggatagcgg cgaaccagct tcccgtagct
     9961 cagagccgta aacaggatcg caatcaatgc gaacgcatag gctgtcggca catgaccatc
    10021 cgtgaggcct gaaacgatac caaaagtatc aaacagcgtc atcggctgca tataggcaag
    10081 acccatcatt acaaccggaa ctaacgtaag cgttttacgc aattccacgc gagaggtgtt
    10141 tggagtaacg ttatgcgaca tggtcattct cctttacggt gataaccgtc gcgtaagcaa
    10201 aaaattgccc catttttttg gattcctcag cgacaacaac tgtcgatttt tagtaaatat
    10261 ctatccggta cgaagcccgg cctcttggta tgaatgattg gtttgaagca aaaaataacc
    10321 gacgctgatg aaacgtcggt ttttagtcat tttttgacag cggcgcattg tgcctaaatg
    10381 ggggggaaat gacaagagaa tgagaggctt gtcataataa tttttcttta aatggctgat
    10441 tttccgtcat cagattttgc ataaacaccg gcgatcgcac tatttgctaa aatttcatcc
    10501 cgccaccagc cactggcaag tcctgcggtc tgttcattcc agccaatcca gacgggttca
    10561 aagagagttt gggcgaccac tttcttctcg attaacgcac cactatcgag aaaacgttgc
    10621 gccagataac ggggtaaata gccgcagccg aggccgctaa tttgcagctc cagcttggtt
    10681 ttaaaatcga aaacggtaat ggcttcttgt tcgtcgagaa gttgtgaggc cgtagaagcg
    10741 cctgcctgcg cagtatcccc caccacaatc gcccgatatc gcttaatgat acgacggttt
    10801 aacggttctt cttccagggc taacggatga tgaggcgcta ccgcaaagac ttgttccaga
    10861 tcgcccaacc gcgagaaacc aaactcactg gaagatggtg gctcatgcat cgcgccaaca
    10921 ataatatccg ctcgcccctg agtcagggca tcccatgaac caccgagtac gccattgata
    10981 aacttcaggc gcgtcacgct atgatgttga taaaaagctt caatcagtgg cgcaagcaga
    11041 gaaaaaggaa acgtgtcgtc cacgccaatc accagttcgt tttcccagcc ttcatgcagt
    11101 ttgatcgcct gcttttccag ttctcgcacg gtatgcagaa cttcccgccc tttctctaat
    11161 aacatttttc cggtgcgggt gaatttagcg cggtgtccgc tacgatcaag caattgaata
    11221 ttaaggtcgc tttccagctt gtgaacggtg taactcagag cggacggcgt cttatagagt
    11281 ttggccgacg ccgccgcaaa actgccttct ttttctaagg catcgaggat catcaacaca
    11341 tccagcagtg gtttcataca cgcccccttg cagtgcatgc ggcgtcctgc tggcgtgatc
    11401 gtttactcca gcggcattac cagcggatcg ggatactggt attcaaatcc cagttcatta
    11461 caaatccgac tgccatcaat aatcttacct ttgccgctgt ccagactatt tctgaactgc
    11521 ggaggctcca gccccagtaa acgggccatc tgcggataga aaacattacg cgcagggtga
    11581 gctggcgcac atatattata gatgtgtccg cctttaggtg cctgtaacaa cagagtgata
    11641 gcgccaataa catcttctaa atggactaaa ttaacaccat gttcaccatc aggcgcggtt
    11701 tttccggcaa agaagcgtcc gggatgacgt cccggtccga ccagccccgc aagacgcaga
    11761 atatcgaccg aagtaccggg taaattgtgc agccagtctt cgagttcttc taatactcgt
    11821 ccactgttgg tcaccggatt acgcggggtg gtttctttca ccgtgccttg cgcgtcgcca
    11881 tagacagacg ttgagctggt aaaaataatt cggggaatac gatgggccag cgcgctatcc
    11941 actaactctt gtaccgcttg taaatagaac tcatcgccgg ggccgctacg acgtgccgga
    12001 agcgtaatga ccagcgcatc ggcatccatc agggcatcca gatcgtcaga atcgcaaact
    12061 aactcaggct ccatgcgaag cagatagctg tcaatgccac tcattcgggc cgcttcgaca
    12121 ccatcttgtg tggttttact cccggtgact tgccagcctc gcgctgaaag tgacatcgcc
    12181 agcggcatgc ctaaccaccc taacccgaca attgcgacct ttttcatccg ttatctcctg
    12241 atacacctta gatctataag gctacgctag cgtatcaaaa ctgacaattc attctatgaa
    12301 tgaatctgtt caataatgat aacgacatgc tgcaatgagc agtgaatcgt cggtaaccgc
    12361 gtataccaga cggtgctcct ctgtaatgcg tcgggaccag aaacctgaca aattatgttt
    12421 caggggttct ggcttcccct taccttcaaa tggcgttctg cgggtatctt tgataagttc
    12481 attgatcttt ttaacaattc gcttatctgt ttcctgccag tacagataat catcccatga
    12541 ttcctcagac cagattagtt tcactcaata atgtcctttt ctgttccttt gcctgatttc
    12601 aggctatcga ttgagtccat caatctccgg gcgttagcgg gggaacgcag tagataagcc
    12661 gtctcttcca gcgagttgta ttcttcgagt gacatcagaa cacaagcctc tccattctga
    12721 cgagtaataa ggatcggggc atgatcttca acggctttca tcattgttgc cgacaaattc
    12781 tgacgcgctt cgctgtagct aattgtacgc atgtcaatct cctcttttgt acagttcatt
    12841 gtacaatgat gggcgttaat taactattta ttaattagtt tgtagatcaa ggtattgtca
    12901 gtgagacgaa aatccaggct tcgctatttt tggtgccgtc agcttagagg acagtcctct
    12961 tagccccctc ctttccccgc tcattcatta aacaaatcca tcgccataaa atatataaaa
    13021 aagcccttgc tttctaacgt gaaagtggtt taggttaaaa gacatcagtt gaataaacat
    13081 tcacagagac ttttatgata cgcgttcaat ttaaacacca ccatcatcac catcatcctg
    13141 actagtcttt caggcgatgt gtgctggaag acattcagat cttccagtgg tgcatgaacg
    13201 catgagaaag cccccggaag atcaccttcc gggggctttt ttattgcgcg gttgataacg
    13261 gttcagacag gtttaaagag gaataacaaa atgacagaca acactcgttt acgcatagct
    13321 atgcagaaat ccggccgttt aagtgatgac tcacgcgaat tgctggcgcg ctgtggcatt
    13381 aaaattaatc ttcacaccca gcgcctgatc gcgatggcag aaaacatgcc gattgatatt
    13441 ctgcgcgtgc gtgacgacga cattcccggt ctggtaatgg atggcgtggt agaccttggg
    13501 attattggcg aaaacgtgct ggaagaagag ctgcttaacc gccgcgccca gggtgaagat
    13561 ccacgctact ttaccctgcg tcgtctggat ttcggcggct gccgtctttc gctggcaacg
    13621 ccagttgatg aagcctggga cggcccgctc tccttaaacg gtaaacgtat cgccacctct
    13681 tatcctcacc tgctcaagcg ttatctcgac cagaaaggca tctcttttaa atcctgctta
    13741 ctgaacggtt ctgttgaagt cgccccgcgt gccggactgg cggatgcgat ttgcgatctg
    13801 gtttccaccg gtgccacgct ggaagctaac ggcctgcgcg aagtcgaagt tatctatcgc
    13861 tcgaaagcct gcctgattca acgcgatggc gaaatggaag aatccaaaca gcaactgatc
    13921 gacaaactgc tgacccgtat tcagggtgtg atccaggcgc gcgaatcaaa atacatcatg
    13981 atgcacgcac cgaccgaacg tctggatgaa gtcatcgccc tgctgccagg tgccgaacgc
    14041 ccaactattc tgccgctggc gggtgaccaa cagcgcgtag cgatgcacat ggtcagcagc
    14101 gaaaccctgt tctgggaaac catggaaaaa ctgaaagcgc tgggtgccag ttcaattctg
    14161 gtgctgccga ttgagaagat gatggagtga tcgccatgag ctttaacaca atcattgact
    14221 ggaatagctg tactgcggag caacaacgcc agctgttaat gcgcccggcg atctccgctt
    14281 ctgaaagcat tacccgcact gttaacgata ttctcgataa cgtgaaagca cgcggcgatg
    14341 aggccctgcg ggaatacagc gcgaagtttg ataaaaccac ggttaccgcg ctgaaggtgt
    14401 ctgctgagga gatcgccgcc gccagcgaac gcctgagcga tgaactaaaa caggcgatgg
    14461 cggtggcagt taagaatgtt gaaaccttcc acactgcgca aaaactgccg ccgatagatg
    14521 tagaaacgca gccaggcgtg cgttgccagc aggtcacgcg cccggtcgct tcagttgggt
    14581 tgtatattcc tggcggctcc gccccgctct tctcaacggt attaatgctg gcgactccgg
    14641 cgcgtattgc gggctgtaaa aaagtggtgc tgtgctcacc gccgccgatt gccgatgaga
    14701 tcctttatgc ggcgcagctg tgcggtgtgc aggacgtgtt taacatcggc ggcgcacagg
    14761 ccattgccgc gctggcgttt ggtacggaat ctgtgccgaa agtggacaaa atcttcgggc
    14821 cgggtaacgc ctttgtcacc gaagcaaaac gccaggtaag ccagcgtctg gacggtgcgg
    14881 cgatcgatat gcccgcaggc ccgtcggaag tgctggtgat tgctgacagc ggcgctacgc
    14941 cggatttcgt ggcttctgat ttgctttctc aggctgaaca cggcccggac tcacaggtga
    15001 ttttactgac gcccgatact gatatggcgc atcaagttgc cgaggccgtc gaacgccaac
    15061 tggcagaact gccgcgtgcc gaaaccgccc gccaggcact gagcgccagc cgcctgatcg
    15121 tgactaaaga tttagcgcag tgcgtagaga tctccaacca gtacggcccg gagcacctga
    15181 tcattcagac ccgcaacgcc cgcgaactgg tcgatggcat caccagcgcc ggttcggtat
    15241 ttcttggtga ctggtcaccg gaatcggcag gcgactatgc ctccggcact aaccatgttc
    15301 taccgactta cggttacacc gccacctgtt ccagcctcgg gctggcagat ttccagaagc
    15361 gcatgaccgt acaggaactg tcgaaagagg ggttctccgc gctggcttca accatagaaa
    15421 cactggccgc cgccgagcgc ctgaccgccc acaaaaatgc cgttactttg cgtgttaacg
    15481 cccttaagga gcaagcatga gcaccgtgac tattaccgat ttagcgcgtg aaaacgtccg
    15541 caacctgacg ccgtatcagt cggcgcgtcg tctgggcggt aatggcgacg tctggctgaa
    15601 cgccaacgaa tatcccacag ccgtggagtt tcagcttact cagcaaacgc tcaaccgcta
    15661 cccggaatgt cagccgaaag cggtgattga aaattacgcg caatatgcag gcgtaaaacc
    15721 ggaacaggtg ctggtcagcc gtggcgcgga cgaaggtatt gaactgctga tccgcgcttt
    15781 ttgcgaaccg ggtaaagact ccatcctcta ctgcccacca acgtacggca tgtacagcgt
    15841 cagcgccgaa acgattggcg tcgagtgccg cacagtgccg acgctggaca actggcaact
    15901 ggacttacag ggcatttccg acaagctgga cggcgtaaaa gtggtctatg tttgcagccc
    15961 caacaacccg accgggcaac tgatcaatcc gcaggatttt cgcaccctgc tggagttaac
    16021 ccgcggtaag gcgattgtgg ttgccgatga agcctatata gagttttgtc cacaggcatc
    16081 gctggctggc tggctggcgg aatatccgca cctggctatt ttgcgcacac tgtcgaaagc
    16141 ttttgctctg gcgggccttc gttgcgggtt tacgctggca aacgaagaag tcatcaacct
    16201 gctgatgaaa gtgatcgccc cctacccgct ctcgacgccg gttgccgaca ttgcggccca
    16261 ggcgttaagc ccgcagggaa tcgtcgccat gcgcgaacgg gtagcgcaaa ttattgcaga
    16321 acgcgaatac ctgattgccg cactgaaaga gatcccctgc gtggagcagg tttttgactc
    16381 tgaaaccaac tacattctgg cgcgctttaa agcctccagt gcagtgttta aatctttgtg
    16441 ggatcagggc attatcttac gtgatcagaa taaacaaccc tctttaagcg gctgcctgcg
    16501 aattaccgtc ggaacccgtg aagaaagcca gcgcgtcatt gacgccttac gtgcggagca
    16561 agtttgatga gtcagaagta tctttttatc gatcgcgatg gaaccctgat tagcgaaccg
    16621 ccgagtgatt ttcaggtgga ccgttttgac aaactcgcct ttgaaccggg cgtgatcccg
    16681 gaactgctga agctgcaaaa agcgggctac aagctggtga tgatcactaa tcaggatggt
    16741 ctgggaacac aaagtttccc gcaggcggat ttcgatggcc cgcacaacct gatgatgcag
    16801 atcttcacct cgcaaggcgt acagtttgat gaagtgctga tttgtccgca cctgcccgcc
    16861 gatgagtgcg actgccgtaa gccgaaagta aaactggtgg aacgttatct ggctgagcaa
    16921 gcgatggatc gcgctaacag ttatgtgatt ggcgatcgcg cgaccgacat tcaactggcg
    16981 gaaaacatgg gcattaatgg tttacgctac gaccgcgaaa tcctgaactg gccaatgatt
    17041 ggcgagcagc tcactaaacg agaccgttac gctcacgtag tgcgcaacac caaagagacg
    17101 cagattgacg ttcaggtgtg gctggatcgc gaaggtggca gcaagattaa caccggtgtt
    17161 ggcttctttg atcacatgct ggatcagatc gccacccacg gcggtttccg tatggaaatc
    17221 aacgtcaaag gcgacctcta tatcgacgat caccacaccg tcgaagatac cggcctggcg
    17281 ctgggtgaag cgttaaaaat tgcccttggc gacaaacgcg gtatttgccg ctttggtttt
    17341 gtgctaccga tggacgaatg ccttgcccgc tgcgcgctgg atatctctgg tcgcccgcac
    17401 ctggaatata aagccgagtt tacctaccag cgcgtgggcg atctcagcac cgaaatgatc
    17461 gagcacttct tccgttcgct ctcatacacc atgggcgtga ccctgcacct gaaaaccaaa
    17521 ggtaaaaacg atcaccaccg tgtagagagc ctgttcaaag cttttggtcg caccctgcgc
    17581 caggccatcc gcgtggaagg cgataccctg ccctcgtcga aaggagtgct gtaatgaacg
    17641 tggtgatcct tgatactggc tgcgccaacc tgaactcggt gaagtctgcc attgcgcgcc
    17701 acggttatga acccaaagtc agccgtgacc cggacgtagt gttgctggcc gataaactat
    17761 ttttacccgg cgtaggcacc gcacaagcag cgatggatca ggtgcgtgag cgcgaactgt
    17821 ttgatctcat caaagcctgt acccaaccgg tgctgggcat ctgcttaggg atgcaactgc
    17881 ttgggcggcg cagcgaagag agcaacggcg tcgatttgct gggcatcatc gacgaagacg
    17941 tgccgaaaat gaccgacttt ggtctaccgc tgccccatat gggctggaac cgcgtttacc
    18001 cgcaggcagg caaccgcctg tttcagggaa ttgaagacgg cgcgtacttt tactttgttc
    18061 acagctacgc aatgccggtt aatccgtgga ccatcgccca gtgtaattac ggcgaaccgt
    18121 tcaccgcggc ggtacaaaaa gataacttct acggcgtgca gttccacccg gagcgttctg
    18181 gtgccgctgg cgctaagctg ctgaaaaact tcctggagat gtgatgatta ttccggcatt
    18241 agatttaatc gacggcactg tggtgcgtct ccatcagggt gattatggca aacagcgcga
    18301 ttacggtaac gacccgctgc cgcgcttaca ggattacgcc gcgcagggtg ccgaagtgct
    18361 gcacctggtg gatctgaccg gggcaaaaga tccggctaaa cgtcaaatcc cgctgattaa
    18421 aactctggtg gcgggcgtta acgttccggt gcaggttggc ggcggcgtgc gtagcgaaga
    18481 agacgtggcg gcgttactgg aagcgggcgt tgcgcgcgtg gtggtcggct ccaccgcggt
    18541 gaaatcacca gaaatggtga aaggctggtt tgaacgtttc ggtgccgatg ccttagtgct
    18601 ggcgctggat gtccgtattg acgagcaagg caacaagcag gtggcggtca gcggctggca
    18661 agagaattcg ggtgtgtcgc tggaacaact ggtggaaacc tatttgcctg tcggcctgaa
    18721 acatgtgctg tgtaccgata tctcgcgcga cggcacgctg gcaggttcta atgtctcttt
    18781 atatgaagaa gtgtgcgcca gatatccgca ggtggcattt cagtcatccg gcggcattgg
    18841 cgacattaac gatgttgctg ccctgcgtgg tactggcgtg cgcggcgtaa tagttggtcg
    18901 ggcattactg gaaggtaaat tcaccgtgaa ggaggccatc gcatgctggc aaaacgtata
    18961 attccgtgtc tcgacgttcg tgatggtcag gtggtgaaag gcgtacagtt tcgcaaccat
    19021 gaaatcattg gcgatatcgt gccgctggca aaacgctacg ccgaagaagg tgcagacgaa
    19081 ctggtgttct acgatatcac cgcttccagc gatggccgtg tggtagataa aagctgggta
    19141 tctcgcgtgg cggaagtgat cgacattccg ttctgtgtgg cgggtgggat taagtctctg
    19201 gaagatgccg cgaaaattct ttcctttggc gcggataaaa tttccatcaa ctcgcctgcg
    19261 ctggcggacc cgacgttaat tactcgcctg gccgatcgct ttggcgtgca gtgtattgtg
    19321 gtgggtattg atacctggta cgacgctgaa accggtaaat atcatgtgaa tcaatatact
    19381 ggcgatgaaa gccgcacccg cgtcactcag tgggaaacgc tcgactgggt acaggaagtg
    19441 caaaaacgcg gtgccggaga aatcgtcctc aacatgatga atcaggacgg cgtgcgtaac
    19501 ggttacgacc tcgaacaact gaaaaaagtg cgtgaagttt gccacgtccc gctaattgcc
    19561 tccggtggcg cgggcaccat ggaacacttc ctcgaagcct tccgcgatgc cgacgttgac
    19621 ggcgcgctgg cggcttccgt attccacaaa caaataatca atattggtga attaaaagcg
    19681 tacctggcaa cacagggcgt ggagatcagg atatgttaac agaacaacaa cgtcgcgaac
    19741 tggactggga aaaaaccgac ggacttatgc cggtgattgt gcagcacgcg gtatccggtg
    19801 aagtgttaat gctgggctat atgaacccgg aagccttaga taaaaccatc gaaagcggca
    19861 aagtcacctt cttctcgcgc actaaacagc gactgtggac caaaggcgaa acgtcgggca
    19921 atttcctcaa cgtagtaaat attgcgccgg actgcgacaa cgacacgcta ctggtactag
    19981 cgaatcctat cggaccaacc tgccacaaag gcaccagcag ctgcttcggc gacaccgctc
    20041 accagtggct gttcctgtat caactggaac aactgctcgc cgaacgcaaa tctgccgacc
    20101 cggaaacctc ttacactgcc aaactgtatg ccagcggcac caaacgcatt gcgcagaaag
    20161 taggtgaaga aggcgtggaa accgcactgg cagcgacggt acatgaccgc tttgagctga
    20221 ccaacgaggc gtctgatttg atgtatcacc tgctggtgct gttgcaggat caggatctgg
    20281 acttaacgac ggtgattgag aacctgcgta aacggcatca gtaagttgcg ggtgatcgga
    20341 tgcgatgttg ttgtcgcatc cggcaaaaaa aacgggcaag gtgtcaccac cctgcccttt
    20401 ttctttaaaa ccgaaaagat tacttcgcgt tgtaattacg cagagcgtta cgccccagca
    20461 caatccccgc accaaccatg ccgcccagca gtaccgccag aatcaaagtg attgcctttt
    20521 tcgggctatc gcgacgaata ggtaacgtcg gtttcatcac atagaggtaa gcatgaatat
    20581 caagatcatc aacttttaag ctttcgatat ccagcaggtt ttgacgtgtc tgatagtagt
    20641 ttggtgagaa caccaacgga cgagtcgctt catgcttaat catcgactcc agcgcttcgc
    20701 tccccaaaag gaacaacgta tcttgtgtca catcttcagt ctgctgaacc tgtggctttg
    20761 tcacctgcgc ctgattcgca tactgcaacg cttcctgaat ctgacggata cgcagatctt
    20821 tctgctcctg cgcaactact tcctgagttt tcagagaatc ctgcaagttt ttcatacgct
    20881 gcgcgatgtt gtctttcagg tcttttccca gttcttcatt tacctggtcg tcaacttgct
    20941 ggatatactt cgccagctgc ttctgagcac cttcaggtgt ttcaccaaca taagacaccg
    21001 ctaaaggtaa tgactgattt ttgacggtag gctcaatggt cagcttttct gcttcttcct
    21061 ggttatccag cgtttccgct aatgctgaga atgcagtgct gtaacgtccg ataagtgaag
    21121 cctgaatgtc ggagactttc ggtacagccg atccgtagat cacattcatc gcgttggtat
    21181 aaccagcgat ttgccccaca tcaggttgag taacgatagc tgtggaagtc cacttttctt
    21241 tggcaacggc cagataccct atagccaggg caatagcaac aatgacagag atgataattg
    21301 tcatcttgcc acgccacaac tgcaccagta aatcaatcaa atcaatctgt tccgggtcat
    21361 ggttttgccc agaaacatta ttattttcta ctctcatcat taccctaacg gacgaaataa
    21421 ttttaagtcg ccatagttta gcgataatcg ccatgaatgc tataggataa atgataaaaa
    21481 taatgaatta ttacaaaggg agcataagac aatcagggcg taaatagccc tgataacaag
    21541 atgttagtcg ctgccaaaga gatcgcgggt gtatacctta tctgccacat ctttaagctc
    21601 ttctgccatt cggttagaga taatgacgtc ggcttgttgt ttgaagatgg cgagatcacg
    21661 ttccaggcga gagttgaaga atgagtcttc tttcatcact ggctcgtaga tgatcacttc
    21721 aacgcctttc gccttgatac gtttcataat cccctgaata gaagacgcac ggaagttatc
    21781 tgaaccgctc ttcataatca gacgataaat acccaccact tgcggtttgc gtgacaaaat
    21841 ggcatcggca ataaaatcct tacgcgtgcg gtttgcatcg acaattgccg agatcaggtt
    21901 attcggcaca gactgatagt tcgccagtaa ctgcttggta tctttcggca aacaataacc
    21961 accataacca aacgacggat tgttgtaatg gttgccaata cgcggatcga gacaaacgcc
    22021 ttcgataatc tggcgagtat tcagacctaa actttctgca tagctatcca gttcattaaa
    22081 gtatgctacg cgcatcgcca gataggtatt agcaaacagt tttatcgctt ctgcttcagt
    22141 ggagtcggta aacagggtcg ggatattttg cttaatcgcg ccttcctgta acaacgcagc
    22201 aaaacgttct gcgcgttctg aacgctcacc aatgacaata cgtgaaggat ggagattatc
    22261 gtaaagggct ttaccttcgc ggaggaattc aggggagaat ataatatttt cagtgcgata
    22321 tttcttatgc atcgctgcag taaaaccaac gggaaccgtt gatttgatca ccataaccgc
    22381 ataaggattt atctcaacta cgtctttaat tactgattct acactggatg tattgaaata
    22441 attagtttta ggatcatagt cggttggagt ggcgatgatg acataatcag cataccggta
    22501 ggcttcattt ttatctaatg tagcattaaa gtgtatttta tctgattgca aaaactgctg
    22561 aatttcctta tcaacaatag gagatatccg atcattcagc atagcaacgc gtgacggtaa
    22621 aatatctaat gccacaacct catgattttg tgcgattaga agcccgtttg acaagcctac
    22681 atagccggta ccggaaatgg tgattttcat ttcatgctct cagaattaac ttaactgtga
    22741 atcatgatgt ttttagcatc ctgataagag ctaaaagttt taacgctacg ttgtcagatg
    22801 gtcaacgcaa cgaaaaacaa ttcagatttt ctttataaga atagctgata tttattaagt
    22861 taatattaag cagtgaaatt tagtctataa gataattggc aaaaaaaagc ccggcgcaat
    22921 atacgccagg cctcaattta ttgttagtta aataagatta atccagccat tcagtatgga
    22981 acacaccttc tttatcaatg cgcttataag tatgtgcacc gaaatagtca cgctgtgcct
    23041 gtatcaggtt cgcaggcaga acagcggcac ggtagctgtc ataataggca accgcagcgg
    23101 cgaaggtggg aaccgggata ccgttctgta ctgcataagc aacaacatca cgcagcgcct
    23161 gctggtagtc atcggcaatt tgcttgaagt acggggccag cagcaggtta gcgatctgcg
    23221 gattttcggc atatgcatcg gtgattttct gcaggaactg cgcacggatg atgcagccag
    23281 cacggaaaat cttcgcgatt tcgccgtagt tcagatccca gttgtactct tcagacgcag
    23341 cacgcagctg agagaagccc tgagcgtaag aaacgatttt gcccagatac agcgcacgac
    23401 gaactttttc gatgaactca gccttgtcgc cagctggctg cgcttgcgga ccagagagaa
    23461 ctttagatgc ggcaacgcgc tgatctttca gagaagagat ataacgtgca aacacagact
    23521 cggtaatcag cgacagcggt tctccgagat ccagcgcgct ctggctggtc catttaccgg
    23581 tacctttgtt agccgcttca tccaggatca catcaaccag gtagttaccg tcttcatctt
    23641 ttttagtgaa gatgtctttg gtgatgtcga tcaggtagct gctcagttca ccgttattcc
    23701 actcggtaaa ggtctgtgcc agttcttcgt tagagagatt caggccgcct ttaagcagag
    23761 aataggcttc agcaatcagc tgcatatcac cgtattcaat accgttatga accatcttca
    23821 catagtgacc tgcaccatcg gcaccaatat aggtaacgca tggctcccca tcttcagcta
    23881 ctgcggcgat tttggtcagg attggtgcaa ccagttcata ggcttctttc tgcccaccag
    23941 gcatgatgga aggtcctttc agcgcacctt cttcaccacc ggaaacaccg gtaccgataa
    24001 agttaaaacc ttcggcagaa agctcacggt tacgacgaat ggtgtcctgg aagaaggtgt
    24061 taccaccatc aatgatgatg tcacctttat cgaggtatgg cttgagggaa tcaatagcag
    24121 catccgtgcc tgcgcctgct ttcaccatta acaggatgcg acgaggcgtt tccaaagatt
    24181 caacaaactc tttcaccgta tagtaaggaa ccagtttctt gcctggattt tcggcaataa
    24241 cttcttccgt cttctcacgg gagcggttga aaatagagac ggtataacca cggctttcga
    24301 tgttgagcgc taggttgcgc cccatcactg ccataccgac tacgccgatc tgttgctttg
    24361 acattgttta ctcctgtcag gggttactgc gaactttaac gcaggtctat atgaagctta
    24421 cggtaactca ggttagaaaa gtattatatt tttactgacg ctaagcaatt cagtttttct
    24481 cagaaaattt ataaccatca ggattgcttt gttgccaatt ccaggcatcg cgaaccatct
    24541 catctaatcc caaacaggct ttccatccaa gttcaaggta tgctttagac gggtcggacc
    24601 aacattcagc aatgtcgcct gctcggcgct caaccaacac ataaggtata ttaacagagg
    24661 ttatccgttg aaaagcagcc aaaagttcaa gaaccgaata accatgccct gtgcctaaat
    24721 tgtaaacctt ataattgcta ccttcatctc ggtgcttcaa ggcagctata tgaccgtttg
    24781 cgagatccat aacatgaata aaatctctaa cgccagtacc atctttagtt tcataatcat
    24841 taccatagat ggataattgc ttatatttac cacttgcaac tgaacatata taaggcatca
    24901 aattatttgg aataccgtta gggtcttctc caatttttcc ggaaggatgt gcgccaacag
    24961 gattaaaata acgcaaaatt gttgttctaa aaaaaggata tgccaaagaa acatcatgta
    25021 atatgttctc aaccataagt tttgaagtcc catagggatt agtagtgcca cctacaggga
    25081 atgtttcttt tacgggtatc ttctctggag taccatatac agtggctgag gagctgaata
    25141 ttagattctt gatattatta ctaatcattt cctcaataag aacaagtgta ccgtatacat
    25201 tattatcgta gtactctgtt gggaattgaa ttgaatcgct tactgatttc aggccagcaa
    25261 aatgaataac atctgttatg ctgttttcag taaagatgga ttttaaaata acacgatctc
    25321 gaatatcacc attaatgata cagatatcac taccagtaat ttctttaacg cgatgcaaag
    25381 attcaactga agaattatga aaattatcaa gcactattac ttcatattgt tctttcagca
    25441 gcattaatac agtatgtgag ccaatatatc cagcaccacc cgtcactaat atagccatac
    25501 aacagcaccc tcatttaatc aaagcaacaa gactagcaga tagaatgtta ttaaagcttg
    25561 gataatttaa taactcttat gcagttataa tattaactaa agaatttgca gattcacttt
    25621 cattaaattt tgacaatgcg aatcttcgac tatttaatcc catagtgaca ataagctcac
    25681 gttcatgaat aaatgtttcc ataactaaag caagtttttg tgtatcccat ggaggtacaa
    25741 gatatccatt atatccatca attactgttt ctcgacaacc tggcacatcg gtcgtaataa
    25801 tcgcacgacc tattgccatt gcttcctgag tacttttggg gacaccttct cgataagaag
    25861 gtaatacaaa gacgctgata tcactcaaat attcttttat ataagagcac ggtcctaaaa
    25921 attcaacata accttccgct ttccaattta caatttgtgc agcatcaatt ccacccggat
    25981 tatcatcaaa atcaccagct atactaaatc ggaccattgg atattttttc tttattattt
    26041 tagccgcttc aacaaattca catacgccct tctctctcaa taatcttgcc accataccaa
    26101 aatggatctc cccacaaatt ggtggatgat aactaaattc attgagattt acacctatgc
    26161 caccaataac tttataatct ttgattttaa tattgttttt aacaaccaag tcatgatagt
    26221 catcattatt aagaaaaaga actttggttg caaaaggtaa tgtcatctta tataaaaaac
    26281 cttgaatctt tcttaagact atttttttaa acgagtcttt atctttatt
//
LOCUS       DAZUDJ010000066        26076 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.066, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000066 DAZUDJ010000000
VERSION     DAZUDJ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26076
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.066"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            201..395
                     /gene="bfd"
                     /locus_tag="ACHY1N_003716"
     CDS             201..395
                     /gene="bfd"
                     /locus_tag="ACHY1N_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HFS4045937.1"
                     /translation="MYVCLCNGVSDKKIRQAVRQFHPQSFQQLRKFIPVGNQCGKCIR
                     AAREVMQDELMQMPEFKEIA"
     gene            468..944
                     /gene="bfr"
                     /locus_tag="ACHY1N_003717"
     CDS             468..944
                     /gene="bfr"
                     /locus_tag="ACHY1N_003717"
                     /EC_number="1.16.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004322 - ferroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006879 - intracellular iron ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HFS4045938.1"
                     /translation="MKGDVKIINYLNKLLGNELVAINQYFLHARMFKNWGLMRLNDVE
                     YHESIDEMKHADKYIERILFLEGIPNLQDLGKLGIGEDVEEMLQSDLRLELEGAKDLR
                     EAIAYADSVHDYVSRDMMIEILADEEGHIDWLETELDLIGKIGLQNYLQSQIKVKD"
     gene            complement(941..1408)
                     /locus_tag="ACHY1N_003718"
     CDS             complement(941..1408)
                     /locus_tag="ACHY1N_003718"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFS4045939.1"
                     /translation="MDANLPFLILYACLSVLLFLWDAKHGLLPDRFTCPLLWSGLLFS
                     QVCNPDGLADALWGAIIGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWTFL
                     PRLVFLAASFACGAVVVGLLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR"
     gene            1787..2098
                     /gene="rpsJ"
                     /locus_tag="ACHY1N_003719"
     CDS             1787..2098
                     /gene="rpsJ"
                     /locus_tag="ACHY1N_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFS4045940.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            2131..2760
                     /gene="rplC"
                     /locus_tag="ACHY1N_003720"
     CDS             2131..2760
                     /gene="rplC"
                     /locus_tag="ACHY1N_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFS4045941.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA"
     gene            2771..3376
                     /gene="rplD"
                     /locus_tag="ACHY1N_003721"
     CDS             2771..3376
                     /gene="rplD"
                     /locus_tag="ACHY1N_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFS4045942.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            3373..3675
                     /gene="rplW"
                     /locus_tag="ACHY1N_003722"
     CDS             3373..3675
                     /gene="rplW"
                     /locus_tag="ACHY1N_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFS4045943.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            3693..4514
                     /gene="rplB"
                     /locus_tag="ACHY1N_003723"
     CDS             3693..4514
                     /gene="rplB"
                     /locus_tag="ACHY1N_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFS4045944.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            4531..4809
                     /gene="rpsS"
                     /locus_tag="ACHY1N_003724"
     CDS             4531..4809
                     /gene="rpsS"
                     /locus_tag="ACHY1N_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFS4045945.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            4824..5156
                     /gene="rplV"
                     /locus_tag="ACHY1N_003725"
     CDS             4824..5156
                     /gene="rplV"
                     /locus_tag="ACHY1N_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFS4045946.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            5174..5875
                     /gene="rpsC"
                     /locus_tag="ACHY1N_003726"
     CDS             5174..5875
                     /gene="rpsC"
                     /locus_tag="ACHY1N_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFS4045947.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            5888..6298
                     /gene="rplP"
                     /locus_tag="ACHY1N_003727"
     CDS             5888..6298
                     /gene="rplP"
                     /locus_tag="ACHY1N_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFS4045948.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            6298..6489
                     /gene="rpmC"
                     /locus_tag="ACHY1N_003728"
     CDS             6298..6489
                     /gene="rpmC"
                     /locus_tag="ACHY1N_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFS4045949.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLNEKAGA"
     gene            6489..6743
                     /gene="rpsQ"
                     /locus_tag="ACHY1N_003729"
     CDS             6489..6743
                     /gene="rpsQ"
                     /locus_tag="ACHY1N_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFS4045950.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKL
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            6908..7279
                     /gene="rplN"
                     /locus_tag="ACHY1N_003730"
     CDS             6908..7279
                     /gene="rplN"
                     /locus_tag="ACHY1N_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015817037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFS4045951.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGP
                     VTRELRSEKFMKIISLAPEVL"
     gene            7290..7604
                     /gene="rplX"
                     /locus_tag="ACHY1N_003731"
     CDS             7290..7604
                     /gene="rplX"
                     /locus_tag="ACHY1N_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFS4045952.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            7619..8158
                     /gene="rplE"
                     /locus_tag="ACHY1N_003732"
     CDS             7619..8158
                     /gene="rplE"
                     /locus_tag="ACHY1N_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFS4045953.1"
                     /translation="MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            8173..8478
                     /gene="rpsN"
                     /locus_tag="ACHY1N_003733"
     CDS             8173..8478
                     /gene="rpsN"
                     /locus_tag="ACHY1N_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFS4045954.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            8512..8904
                     /gene="rpsH"
                     /locus_tag="ACHY1N_003734"
     CDS             8512..8904
                     /gene="rpsH"
                     /locus_tag="ACHY1N_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFS4045955.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            8917..9450
                     /gene="rplF"
                     /locus_tag="ACHY1N_003735"
     CDS             8917..9450
                     /gene="rplF"
                     /locus_tag="ACHY1N_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFS4045956.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     INLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            9460..9813
                     /gene="rplR"
                     /locus_tag="ACHY1N_003736"
     CDS             9460..9813
                     /gene="rplR"
                     /locus_tag="ACHY1N_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFS4045957.1"
                     /translation="MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            9828..10331
                     /gene="rpsE"
                     /locus_tag="ACHY1N_003737"
     CDS             9828..10331
                     /gene="rpsE"
                     /locus_tag="ACHY1N_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFS4045958.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            10335..10514
                     /gene="rpmD"
                     /locus_tag="ACHY1N_003738"
     CDS             10335..10514
                     /gene="rpmD"
                     /locus_tag="ACHY1N_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFS4045959.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAI
                     RGMINAVSFMVKVEE"
     gene            10518..10952
                     /gene="rplO"
                     /locus_tag="ACHY1N_003739"
     CDS             10518..10952
                     /gene="rplO"
                     /locus_tag="ACHY1N_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFS4045960.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            10960..12291
                     /gene="secY"
                     /locus_tag="ACHY1N_003740"
     CDS             10960..12291
                     /gene="secY"
                     /locus_tag="ACHY1N_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFS4045961.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            12323..12439
                     /gene="rpmJ"
                     /locus_tag="ACHY1N_003741"
     CDS             12323..12439
                     /gene="rpmJ"
                     /locus_tag="ACHY1N_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFS4045962.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            12586..12942
                     /gene="rpsM"
                     /locus_tag="ACHY1N_003742"
     CDS             12586..12942
                     /gene="rpsM"
                     /locus_tag="ACHY1N_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFS4045963.1"
                     /translation="MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVK
                     ISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPRKPIKK"
     gene            12959..13348
                     /gene="rpsK"
                     /locus_tag="ACHY1N_003743"
     CDS             12959..13348
                     /gene="rpsK"
                     /locus_tag="ACHY1N_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFS4045964.1"
                     /translation="MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            13382..14002
                     /gene="rpsD"
                     /locus_tag="ACHY1N_003744"
     CDS             13382..14002
                     /gene="rpsD"
                     /locus_tag="ACHY1N_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFS4045965.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK"
     gene            14028..15017
                     /gene="rpoA"
                     /locus_tag="ACHY1N_003745"
     CDS             14028..15017
                     /gene="rpoA"
                     /locus_tag="ACHY1N_003745"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFS4045966.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            15058..15441
                     /gene="rplQ"
                     /locus_tag="ACHY1N_003746"
     CDS             15058..15441
                     /gene="rplQ"
                     /locus_tag="ACHY1N_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFS4045967.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKAEAAAE"
     gene            15548..15916
                     /locus_tag="ACHY1N_003747"
     CDS             15548..15916
                     /locus_tag="ACHY1N_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HFS4045968.1"
                     /translation="MWLLDQWAERHIAEAQAKGEFDNLAGSGEPLILDDDSHVPPELR
                     AGYRLLKNAGCLPPELEQRREAIQLLDILKGIRHDDPQYQEVSRRLSLLELKLRQAGL
                     STDFLRGDYADKLLNKINDN"
     gene            15927..16352
                     /gene="zntR"
                     /locus_tag="ACHY1N_003748"
     CDS             15927..16352
                     /gene="zntR"
                     /locus_tag="ACHY1N_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HFS4045969.1"
                     /translation="MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESD
                     LQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQS
                     MQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC"
     gene            16408..16626
                     /gene="arfA"
                     /locus_tag="ACHY1N_003749"
     CDS             16408..16626
                     /gene="arfA"
                     /locus_tag="ACHY1N_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor ArfA"
                     /protein_id="HFS4045970.1"
                     /translation="MSRYQHTKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYMRKGK
                     HGNRGNWEASGKKVNHFFTTGLLLSGVC"
     gene            complement(16623..17033)
                     /gene="mscL"
                     /locus_tag="ACHY1N_003750"
     CDS             complement(16623..17033)
                     /gene="mscL"
                     /locus_tag="ACHY1N_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFS4045971.1"
                     /translation="MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL
                     NRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS"
     gene            complement(17163..18539)
                     /gene="trkA"
                     /locus_tag="ACHY1N_003751"
     CDS             complement(17163..18539)
                     /gene="trkA"
                     /locus_tag="ACHY1N_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HFS4045972.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            complement(18561..19850)
                     /gene="rsmB"
                     /locus_tag="ACHY1N_003752"
     CDS             complement(18561..19850)
                     /gene="rsmB"
                     /locus_tag="ACHY1N_003752"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFS4045973.1"
                     /translation="MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALL
                     QELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAET
                     VEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQ
                     WQSIVEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVH
                     ALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAV
                     DIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRH
                     PDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQR
                     TADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK"
     gene            complement(19896..20843)
                     /gene="fmt"
                     /locus_tag="ACHY1N_003753"
     CDS             complement(19896..20843)
                     /gene="fmt"
                     /locus_tag="ACHY1N_003753"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFS4045974.1"
                     /translation="MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRG
                     KKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPIT
                     AEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVA
                     TGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV"
     gene            complement(20858..21367)
                     /gene="def"
                     /locus_tag="ACHY1N_003754"
     CDS             complement(20858..21367)
                     /gene="def"
                     /locus_tag="ACHY1N_003754"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFS4045975.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVE
                     KLDRLKARA"
     gene            21497..22621
                     /gene="dprA"
                     /locus_tag="ACHY1N_003755"
     CDS             21497..22621
                     /gene="dprA"
                     /locus_tag="ACHY1N_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HFS4045976.1"
                     /translation="MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGL
                     TLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSEFYPPQLQATTDYPGALFVEGEL
                     HALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
                     GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGL
                     SKGVLVVEAALRSGSLVTARCALEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEP
                     EEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDEVTPVDVVAERAGQP
                     VPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV"
     gene            22593..23066
                     /gene="smg"
                     /locus_tag="ACHY1N_003756"
     CDS             22593..23066
                     /gene="smg"
                     /locus_tag="ACHY1N_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 family protein Smg"
                     /protein_id="HFS4045977.1"
                     /translation="MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNAL
                     LWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLET
                     REMVIERVLALDNAEFELDDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            23095..23637
                     /locus_tag="ACHY1N_003757"
     CDS             23095..23637
                     /locus_tag="ACHY1N_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HFS4045978.1"
                     /translation="MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACDYV
                     RPLKSSADGHIVKVLEGQVCPACGENLVLRQGRFGMFIGCSNYPECEHTELIDKPDET
                     AITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKT
                     AQGVKHFCASKQCGKPVSAE"
     gene            23642..24214
                     /gene="tsaC"
                     /locus_tag="ACHY1N_003758"
     CDS             23642..24214
                     /gene="tsaC"
                     /locus_tag="ACHY1N_003758"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HFS4045979.1"
                     /translation="MNNNLQGDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVM
                     RLLELKQRPVDKGLILIAANYEQLKPYIDDTMLTDAQRETIFSRWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTDHPLVVALCQAYGKPLVSTSANLSGLPPCRTVDEVRAQFGA
                     AFPVVPGETGGRLNPSEIRDALTGELFRQG"
     gene            24219..25037
                     /gene="aroE"
                     /locus_tag="ACHY1N_003759"
     CDS             24219..25037
                     /gene="aroE"
                     /locus_tag="ACHY1N_003759"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFS4045980.1"
                     /translation="METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFI
                     NTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLQGDNTD
                     GIGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAK
                     LFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKG
                     KTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA"
     gene            25034..25291
                     /locus_tag="ACHY1N_003760"
     CDS             25034..25291
                     /locus_tag="ACHY1N_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HFS4045981.1"
                     /translation="MNQAIQFPDREEWDENKKCVCFPALVNGMQLTCAISGESLAYRF
                     TGDTPEQWLASFRQHRWDLEEEAENLIQEQSEDDQGWVWLP"
     gene            complement(25267..25821)
                     /locus_tag="ACHY1N_003761"
     CDS             complement(25267..25821)
                     /locus_tag="ACHY1N_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417738.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFS4045982.1"
                     /translation="MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVV
                     IRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGN
                     RVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAG
                     LRYSANNYVKWKDEYLDQGNQTQP"
BASE COUNT         6706 a         6182 c         6754 g         6434 t
ORIGIN      
        1 gctaaagttc tgggctaatt acacgttaat tagttttgaa ttgaaaaggg cgcttcggcg
       61 ccctttttgc tgcccgtaat ttgagctcga aatatttagt cgtaattttg ctcgctgaac
      121 tatggcgcaa ataaaactgt gctattgtaa tcataaccat tctcatttac actttgcgca
      181 gaatttgaac gggagcaatc atgtacgttt gtttgtgtaa tggtgtaagt gacaaaaaaa
      241 ttcgccaggc agtccgtcag tttcatccgc aatctttcca acaattgcgt aagtttattc
      301 ctgtgggaaa tcaatgcggt aagtgcattc gcgccgcgcg cgaagtgatg caggacgagt
      361 tgatgcagat gccagaattt aaagagattg cctgaagacc acgcttattt tttgacatcc
      421 cgctagcccc atctacgctc taatagtgga agcggaggga ctataaaatg aaaggtgatg
      481 ttaaaatcat aaattatctc aataaactat tgggaaatga gcttgtcgca atcaatcagt
      541 attttctcca tgcccggatg tttaaaaact ggggcctgat gcgtctcaat gacgtcgaat
      601 accatgaatc catcgatgag atgaaacacg ctgataaata tatcgagcgt attttgtttt
      661 tagaaggaat ccccaactta caggatttag gcaaactggg gattggtgaa gatgtcgagg
      721 agatgctgca atccgacctg cgattagaac tggaaggcgc gaaggatctc cgtgaggcta
      781 tcgcgtatgc cgacagcgtt catgactatg ttagccgtga tatgatgatc gagatccttg
      841 ccgatgaaga aggtcatatt gactggctcg aaactgagct ggatctcatc ggtaaaatcg
      901 gtttacaaaa ttacctgcaa tcacaaataa aagttaaaga ttaacggcct gccagcaaac
      961 tatcccaacc tacaacgaaa cccgcagccg ccagaaatgg cccaaacggc agcgggtttt
     1021 ttaatgactc ttttcctctc atgagcagac caacaactac ggctccgcaa gcgaatgagg
     1081 cagcaaggaa aaccagtcgt ggcaagaagg tccaggtatg ccaggcacca agggcggcga
     1141 gaaacttcac atcaccatag cctaatcctt ctttatgacg cagtatgcga tacccccagt
     1201 aaatgacagc gaatgtgccg taaccaataa tcgcccccca taacgcatcg gctaaaccgt
     1261 caggattaca aacctgagag aacaaaagac ctgaccagag taacgggcag gtaaatctgt
     1321 caggtaacaa gccatgcttt gcatcccata aaaaaagtag gacagataaa caagcgtaca
     1381 aaatcagaaa gggaaggtta gcgtccataa aacatcctct gtaattggag tatcaccatc
     1441 gaataactcc ggatgctcag caacagagaa atcgctgatt tgttaacctg gttccggtga
     1501 aaaacgctat cttcacaacc ttacaaattt cgtggaatac agctcgcaat ctgcgcgttg
     1561 cgattaattt ctacccgatg cttgcgtcag gctcagattt gcgtataatg cgcgggcttg
     1621 tcgtagttga cagcaggttc aatctgaacc tcagttagcc gaatttggct acctaacaat
     1681 gctcccaatc ggggagctac gtaagaacgg ttacactctc ccatcaatcg taatgggtct
     1741 gaggagtaat cattttcgtt tataaaataa ttggagctct ggtctcatgc agaaccaaag
     1801 aatccgtatc cgcctgaaag cgtttgatca tcgtctgatc gatcaagcaa ccgcggaaat
     1861 cgtcgagact gccaagcgca ctggtgcgca ggtccgtggt ccgatcccgc tgccgacacg
     1921 caaagagcgc ttcactgttc tgatctcccc gcacgtcaac aaagacgcgc gcgatcagta
     1981 cgaaatccgt actcacttgc gtctggttga catcgttgag ccaaccgaga aaaccgttga
     2041 tgctctgatg cgtctggatc tggctgccgg tgtagacgtg cagatcagcc tgggttaatc
     2101 aggtcattga gcgattgaga ggttgaaaca atgattggtt tagtcggtaa aaaagtgggt
     2161 atgacccgta tcttcacaga agacggcgtt tctatcccag taaccgtaat cgaagttgaa
     2221 gcaaaccgcg ttactcaggt taaagacctg gctaacgatg gctaccgtgc tattcaggtg
     2281 accaccggtg ctaaaaaagc taaccgtgtg accaagcctg aagctggcca cttcgctaaa
     2341 gctggcgtag aagctggccg tggtctgtgg gaattccgcc tggctgaagg cgaagagttc
     2401 actgtaggtc agagcattag cgttgaactg tttgctgacg ttaaaaaagt tgacgtaact
     2461 ggcacctcta aaggtaaagg tttcgcaggt accgttaagc gctggaactt ccgtacccag
     2521 gacgctactc acggtaactc cttgtctcac cgcgttccgg gttctatcgg tcagaaccag
     2581 actccgggca aagtgttcaa aggcaagaaa atggcaggtc agatgggtaa cgaacgtgta
     2641 accgttcaga gccttgacgt agtacgcgtt gacgctgagc gcaacctgct gctggttaaa
     2701 ggtgctgtcc cgggtgcaac cggtagcgac ctgatcgtta aaccagctgt gaaggcgtaa
     2761 ggagatagca atggaattag tattgaaaga cgcgcagagc gcgctgactg tttccgaaac
     2821 taccttcggt cgtgatttca acgaagcgct ggttcaccag gttgttgttg cttatgcagc
     2881 tggtgctcgt cagggtactc gtgctcagaa gactcgtgct gaagtaactg gttccggtaa
     2941 aaaaccgtgg cgccagaaag gcaccggccg tgcgcgttct ggttctatca agagcccgat
     3001 ctggcgttct ggtggcgtga cctttgctgc tcgtccgcag gaccacagtc aaaaagttaa
     3061 caagaagatg taccgcggcg cgctgaaaag catcctgtcc gaactggtac gtcaggatcg
     3121 tctgatcgtt gtcgagaagt tctctgtaga agcgccgaaa actaagctgc tggcacagaa
     3181 actgaaagac atggctctgg aagatgtgct gatcatcacc ggtgagctgg acgaaaacct
     3241 gttcctggct gcgcgcaacc tgcacaaggt tgacgtacgc gatgcaactg gtatcgaccc
     3301 ggttagcctg atcgccttcg acaaagtcgt aatgactgct gatgctgtta agcaagttga
     3361 ggagatgctg gcatgattcg tgaagaacgt ctgctgaagg tgctgcgtgc accgcacgtt
     3421 tctgaaaaag cgtctactgc gatggaaaaa tccaacacca tcgtactcaa agttgctaaa
     3481 gacgcgacca aagcagaaat caaagctgct gtgcagaaac tgtttgaagt cgaagtcgaa
     3541 gtcgttaaca ccctggtagt taaagggaaa gttaaacgtc acggacagcg tatcggtcgt
     3601 cgtagcgact ggaaaaaagc ttacgtcacc ctgaaagaag gccagaatct ggacttcgtt
     3661 ggcggcgctg agtaagtcgg aggagtaata caatggcagt tgttaaatgt aaaccgacat
     3721 ctccgggtcg tcgccacgta gttaaagtgg ttaaccctga gctgcacaag ggcaaacctt
     3781 ttgctccgtt gctggaaaaa aacagcaaat ccggtggtcg taacaacaat ggccgtatca
     3841 ccactcgtca tatcggtggt ggccacaagc aggcttaccg tattgttgac ttcaaacgca
     3901 acaaagacgg tatcccggca gttgttgaac gtcttgagta cgatccgaac cgttccgcga
     3961 acatcgcgct ggttctgtac aaagacggtg aacgccgtta catcctggcc cctaaaggcc
     4021 tgaaagctgg cgaccagatt cagtctggcg ttgatgctgc aatcaaacca ggtaacaccc
     4081 tgccgatgcg caacatcccg gttggttcta ctgttcataa cgtagaaatg aaaccaggta
     4141 aaggcggtca gctggcacgt tccgctggta cttacgttca gatcgttgct cgtgatggtg
     4201 cttatgtcac cctgcgtctg cgttctggtg aaatgcgtaa agtagaagca gactgccgtg
     4261 caactctggg cgaagttggc aatgctgagc atatgctgcg cgttctgggt aaagcaggtg
     4321 ctgcacgctg gcgtggtgtt cgtccgaccg ttcgcggtac cgcgatgaac ccggtagacc
     4381 acccacatgg tggtggtgaa ggtcgtaact ttggtaagca cccggtaact ccgtggggcg
     4441 ttcagaccaa aggtaagaag acccgcagca acaagcgtac tgataaattc atcgtacgtc
     4501 gccgtagcaa ataattttag aggataagcc atgccacgtt ctctcaagaa aggtcctttt
     4561 attgacctgc acttgctgaa gaaggtagag aaagcggtgg aaagcggaga caagaagccc
     4621 ctgcgcactt ggtcccgtcg ttcaacgatc tttcctaaca tgatcggttt gaccatcgct
     4681 gtccataatg gtcgtcagca cgttccggta tttgtaaccg acgaaatggt cggtcacaaa
     4741 ctgggtgaat tcgcaccgac tcgtacttat cgcggccacg ctgctgataa aaaagcgaag
     4801 aagaaataag gtaggaggaa gagatggaaa ctatcgctaa acatcgccat gctcgttctt
     4861 ctgctcagaa ggttcgcctt gttgctgacc tgattcgcgg taagaaagtg tcgcaggctc
     4921 tggatatttt gacctacacc aacaagaaag cggctgtact ggtcaagaaa gttctggaat
     4981 ctgccattgc taacgctgaa cacaacgatg gcgctgacat tgacgatctg aaagttacga
     5041 aaattttcgt agacgaaggc ccgagcatga agcgcattat gccgcgtgca aaaggtcgtg
     5101 cagatcgcat cctgaagcgc accagccaca tcactgtggt tgtgtccgat cgctgagact
     5161 ctggagacta gcaatgggtc agaaagtaca tcctaatggt attcgcctgg gtattgtaaa
     5221 accatggaac tctacctggt ttgcgaacac caaagaattc gctgacaacc tggacagcga
     5281 ttttaaagta cgtcagtacc tgactaagga actggctaaa gcgtccgtat ctcgtatcgt
     5341 tatcgagcgt ccggctaaga gcatccgtgt aaccattcac actgctcgcc cgggtatcgt
     5401 tatcggtaaa aaaggtgaag acgtagaaaa actgcgtaag gtcgtagcgg acatcgctgg
     5461 cgttcctgca cagatcaaca tcgccgaagt tcgtaagcct gaactggacg caaaactggt
     5521 tgctgacagc atcacttctc agctggaacg tcgcgttatg ttccgtcgtg ctatgaagcg
     5581 tgctgtacag aacgcaatgc gtctgggcgc taaaggtatt aaagttgaag ttagcggccg
     5641 tctgggcggc gcggaaatcg cacgtaccga atggtaccgc gaaggtcgcg taccgctgca
     5701 cactctgcgt gctgacatcg actacaacac ctctgaagcg cacaccactt acggtgtaat
     5761 cggcgttaaa gtgtggatct tcaaaggcga gatcctgggt ggtatggctg ctgttgaaca
     5821 accggaaaaa ccggctgctc agcctaaaaa gcagcagcgt aaaggccgta aataaggagc
     5881 gtcgctgatg ttacaaccaa agcgtacaaa attccgtaaa atgcacaaag gccgtaaccg
     5941 cggtctggcg cagggtacgg atgttagctt cggcagcttc ggtctgaaag ctgttggccg
     6001 tggtcgtctg actgcccgtc agatcgaagc agcacgtcgt gctatgaccc gtgcagttaa
     6061 gcgtcaaggt aagatctgga tccgtgtgtt cccggacaaa ccgatcactg aaaagccgct
     6121 ggcagtgcgt atgggtaaag gtaaaggtaa cgtggagtat tgggttgcct tgattcagcc
     6181 gggtaaagtc ctgtatgaaa tggacggtgt tccggaagag ctggcccgtg aagcattcaa
     6241 gctggcagca gcgaaactgc cgattaaaac cacctttgta actaagacgg tgatgtaatg
     6301 aaagcaaaag agctgcgtga gaagagcgtt gaagagctga acaccgagct gctgaacctg
     6361 ctgcgtgagc agttcaacct gcgtatgcag gctgcaagtg gccagctgca acagtctcac
     6421 ctgttgaagc aagtgcgtcg cgatgtcgca cgcgttaaga ctttactgaa cgagaaggcg
     6481 ggtgcgtaat gaccgataaa atccgtactc tgcaaggtcg cgttgttagc gacaaaatgg
     6541 agaaatccat tgttgttgct atcgaacgtt ttgtgaaaca cccgatctac ggtaaattca
     6601 tcaagcgtac gaccaaactg cacgtacatg acgagaacaa cgaatgcggt atcggtgacg
     6661 tggttgaaat ccgcgaatgc cgtccgctgt ccaagactaa atcctggacg ctggttcgcg
     6721 ttgtagagaa agcggttctg taatacagta cactctctcg atacgaataa acggctcaga
     6781 aatgagccgt ttattttttc tacccatatc cttgaagcgg tgttataatg ccgcgccctc
     6841 gatatgggga tttttaacga cctgattttc gggtctcagt agtagttgac attagcggag
     6901 cactaaaatg atccaagaac agactatgct gaacgtcgcc gacaactccg gtgcacgtcg
     6961 cgtaatgtgt atcaaggttc tgggtggctc gcaccgtcgc tacgcaggcg taggcgacat
     7021 catcaagatc accatcaaag aagcaattcc gcgtggtaag gtcaaaaaag gtgatgtgct
     7081 gaaggcggta gtggtgcgca ccaagaaggg tgttcgtcgc ccggacggtt ctgtcattcg
     7141 cttcgatggt aatgcttgtg ttcttctgaa caacaacagc gagcagccta tcggtacgcg
     7201 tatttttggg ccggtaactc gtgagcttcg tagtgagaag ttcatgaaaa ttatctctct
     7261 ggcaccagaa gtactctaag gagcgaatca tggcagcgaa aatccgtcgt gatgacgaag
     7321 ttatcgtgtt aaccggtaaa gataaaggta aacgcggtaa agttaagaat gtcctgtctt
     7381 ccggcaaggt cattgttgaa ggtatcaacc tggttaagaa acatcagaag ccggttccgg
     7441 ccctgaacca accgggtggc atcgttgaaa aagaagccgc tattcaggtt tccaacgtag
     7501 caatcttcaa tgcggcaacc ggcaaggctg accgtgtagg ctttagattc gaagacggca
     7561 aaaaagtccg tttcttcaag tctaacagcg aaactatcaa gtaatttgga gtagtacgat
     7621 ggcgaaactg catgattact acaaagacga agtagttaaa aaactcatga ctgagtttaa
     7681 ctacaattct gtcatgcaag tccctcgggt cgagaagatc accctgaaca tgggtgttgg
     7741 tgaagcgatc gctgacaaaa aactgctgga taacgcagca gcagacctgg cagcaatctc
     7801 cggtcaaaaa ccgctgatca ccaaagcacg caaatctgtt gcaggcttca aaatccgtca
     7861 gggctatccg atcggctgta aagtaactct gcgtggcgaa cgcatgtggg agttctttga
     7921 gcgcctgatc actattgctg tacctcgtat ccgtgacttc cgtggcctgt ccgctaagtc
     7981 tttcgacggt cgtggtaact acagcatggg tgtccgtgag cagatcatct tcccagaaat
     8041 cgactacgat aaagtcgacc gcgttcgtgg tttggatatt accattacca ctactgcgaa
     8101 atctgacgaa gaaggccgcg ctctgctggc tgcctttgac ttcccgttcc gcaagtaagg
     8161 tagggttact aaatggctaa gcaatcaatg aaagcacgcg aagtaaaacg cgtagcttta
     8221 gctgataaat acttcgcgaa acgcgctgaa ctgaaagcga tcatctctga tgtgaacgct
     8281 tccgacgaag atcgttggaa cgctgttctc aagctgcaga ctctgccgcg tgattccagc
     8341 ccgtctcgtc agcgtaaccg ctgccgtcaa acaggtcgtc cgcatggttt cctgcggaag
     8401 ttcgggttga gccgtattaa ggtccgtgaa gccgctatgc gcggtgaaat cccgggtctg
     8461 aaaaaggcta gctggtaatt gtcaccaatt gaatcacggg agtaaagaca gatgagcatg
     8521 caagatccga tcgcggatat gctgacccgt atccgtaacg gtcaggccgc gaacaaagct
     8581 gcggtcacca tgccttcctc caagctgaaa gtggcaatcg ccaacgtgct gaaggaagaa
     8641 ggttttattg aagattttaa agttgaaggc gacaccaagc ctgaactgga acttactctg
     8701 aagtatttcc agggcaaagc tgttgtagaa agcattcagc gtgtcagccg cccaggtctg
     8761 cgcatctata aacgtaaaga tgagctgccg aaagttatgg cgggtctggg tatcgcagtt
     8821 gtttctacct ctaaaggtgt tatgactgat cgtgcagcgc gccaggctgg tcttggtggc
     8881 gaaattatct gctacgtagc ctaatcggag gaaaaaatgt ctcgtgttgc taaagcaccg
     8941 gtcgttgttc ctgccggcgt tgacgtaaaa atcaacggtc aggttattac gatcaaaggt
     9001 aaaaacggcg agctgactcg tactctcaac gatgctgttg aagttaaaca tgcagataat
     9061 accctgacct tcggtccgcg tgatggttac gcagacggtt gggcacaggc tggtaccgcg
     9121 cgtgccctgc tgaactcaat ggttatcggt gttaccgaag gcttcactaa gaagctgcag
     9181 ctggttggtg taggttaccg tgcagcggtt aaaggcaatg tgattaacct gtctctgggt
     9241 ttctctcatc ctgttgacca tcagctgcct gcgggtatca ctgctgaatg tccgactcag
     9301 actgaaatcg tgctgaaagg cgctgataag caggtgatcg gccaggttgc agcggatctg
     9361 cgcgcctacc gtcgtcctga gccttataaa ggcaagggtg ttcgttacgc cgacgaagtc
     9421 gtgcgtacca aagaggctaa gaagaagtaa ggtaacacta tggataagaa atctgctcgt
     9481 atccgtcgtg cgacccgcgc acgccgcaag ctccaggagc tgggcgcaac tcgcctggtg
     9541 gtacatcgta ccccgcgtca catttacgca caggtaattg caccgaacgg ttctgaagtt
     9601 ctggtagctg cttctactgt agaaaaagct atcgctgaac aactgaagta caccggtaac
     9661 aaagacgcgg ctgcagctgt gggtaaagct gtcgctgaac gcgctctgga aaaaggcatc
     9721 aaagatgtat cctttgaccg ttccgggttc caatatcatg gtcgtgtcca ggcactggca
     9781 gatgctgccc gtgaagctgg ccttcagttc taaggtagag gtgtaagatg gctcacatcg
     9841 aaaaacaagc tggcgaactg caggaaaagc tgatcgcggt aaaccgcgta tctaaaaccg
     9901 ttaaaggtgg tcgtattttc tccttcacag ctctgactgt agttggcgat ggtaacggtc
     9961 gcgttggttt tggttacggt aaagcgcgtg aagttccagc agcgatccag aaagcgatgg
    10021 aaaaagcccg tcgcaatatg attaacgtcg cgctgaataa cggcactctg caacaccctg
    10081 ttaaaggtgt tcacacgggt tctcgcgtat tcatgcagcc ggcttccgaa ggtaccggta
    10141 tcatcgccgg tggtgcaatg cgcgccgttc tggaagtcgc tggggttcat aacgttctgg
    10201 ctaaagcata tggttccacc aacccgatca acgtggttcg tgcaactatt gatggcctgg
    10261 aaaatatgaa ttctccagaa atggtcgctg ccaagcgtgg taaatccgtt gaagaaattc
    10321 tggggaaata aaccatggca aagactatta aaattactca aacccgcagt gcaatcggtc
    10381 gtctgccgaa acacaaggca acgctgcttg gcctgggtct gcgtcgtatt ggtcacaccg
    10441 tagagcgcga ggatactcct gctattcgcg gtatgatcaa cgcggtttcc ttcatggtta
    10501 aagttgagga gtaagagatg cgtttaaata ctctgtctcc ggccgaaggc tccaaaaagg
    10561 cgggtaaacg cctgggtcgt ggtatcggtt ctggcctcgg taaaaccggt ggtcgtggtc
    10621 acaaaggtca gaaatctcgt tctggcggtg gcgtacgtcg cggtttcgag ggtggtcaga
    10681 tgcctctgta ccgtcgtctg ccgaaattcg gcttcacttc tcgtaaagca gcgattacag
    10741 ccgaagttcg tctgtctgac ctggctaaag tagaaggcgg tgttgtagac ctgaacacgc
    10801 tgaaagcggc taacattatc ggtatccaga tcgagttcgc gaaagtgatc ctggctggcg
    10861 aagtaacgac tccggtaact gttcgtggcc tgcgtgttac taaaggcgct cgtgctgcta
    10921 tcgaagctgc tggcggtaaa atcgaggaat aagtagcaga tggctaaaca accgggatta
    10981 gattttcaaa gtgccaaagg tggcttaggc gagctgaaac gcagactgct gtttgttatc
    11041 ggtgcgctga ttgtgttccg tattggctct tttattccga tccctggtat tgatgccgct
    11101 gtacttgcca aactgcttga gcaacagcga ggcaccatca ttgagatgtt taacatgttc
    11161 tctggtggtg ctctcagccg tgcttctatc tttgctctgg ggatcatgcc gtatatttcg
    11221 gcgtcgatca ttatccagct gctgacggtg gttcacccaa cgttggcaga aattaagaaa
    11281 gaaggggagt ctggtcgtcg taagatcagc cagtacaccc gttacggtac tctggtgctg
    11341 gcaatattcc agtcgatcgg tattgctacc ggtctgccga atatgcctgg tatgcaaggc
    11401 ctggtgatta acccaggctt tgcattctac ttcaccgctg ttgtaagtct ggtcacagga
    11461 acgatgttcc tgatgtggtt gggcgaacag attactgaac gaggtatcgg caacggtatt
    11521 tcaatcatta tcttcgccgg tattgtcgcg ggactcccgc cagccattgc ccatactatc
    11581 gagcaagcgc gtcaaggcga cctgcacttc ctcgtgttgc tgttggttgc agtattagta
    11641 tttgcagtga cgttctttgt tgtatttgtt gagcgtggtc aacgccgcat tgtggtaaac
    11701 tacgcgaaac gtcagcaagg tcgtcgtgtc tatgctgcac agagcacaca tttaccgctg
    11761 aaagtgaata tggcgggggt aatcccggca atcttcgctt ccagtattat tctgttcccg
    11821 gcgaccatcg cgtcatggtt cgggggcggt actggttgga actggctgac aacaatttcg
    11881 ctgtatttgc agcctgggca accgctttat gtgttactct atgcgtctgc aatcatcttc
    11941 ttctgtttct tctacacggc gttggttttc aacccgcgtg aaacagcaga taacctgaag
    12001 aagtccggtg catttgtacc aggaattcgt ccgggagagc aaacggcgaa gtatatcgat
    12061 aaagtaatga cccgcctgac cctggttggt gcgctgtata ttacctttat ctgcctgatc
    12121 ccggagttca tgcgtgatgc aatgaaagta ccgttctact tcggtgggac ctcactgctt
    12181 atcgttgttg tcgtgattat ggactttatg gctcaagtgc aaactctgat gatgtccagt
    12241 cagtatgagt ctgcattgaa gaaggcgaac ctgaaaggct acggccgata attggtcgcc
    12301 cgagaagtta cggagagtaa aaatgaaagt tcgtgcttcc gtcaagaaat tatgccgtaa
    12361 ctgcaaaatc gttaagcgtg atggtgtcat ccgtgtgatt tgcagtgccg agccgaagca
    12421 taaacagcgc caaggctgat tttttcgcat atttttcttg caaagttggg ttgagctggc
    12481 tagattagcc agccaatctt ttgtatgtct gtgcgtttcc atttgagtat cctgaaaacg
    12541 ggcttttcag catggaacgt acatattaaa tagtaggagt gcatagtggc ccgtatagca
    12601 ggcattaaca ttcctgatca taagcatgcc gtaatcgcat taacttcgat ttatggcgtc
    12661 ggcaagaccc gttctaaagc catcctggct gcagcgggta tcgctgaaga tgttaagatc
    12721 agtgagctgt ctgaaggaca aatcgacacg ctgcgtgacg aagttgccaa atttgtcgtt
    12781 gaaggtgatc tgcgccgtga aatcagcatg agcatcaagc gcctgatgga tcttggttgc
    12841 tatcgcggtt tgcgtcatcg tcgtggtctc ccggttcgcg gtcagcgtac caagaccaac
    12901 gcacgtaccc gtaagggtcc gcgcaaaccg atcaagaaat aatcggggtg attgaataat
    12961 ggcaaaggca ccaattcgtg cacgtaaacg tgtaagaaaa caagtctctg acggcgtggc
    13021 tcatatccat gcttctttca acaacaccat cgtgactatc actgatcgtc agggtaacgc
    13081 gttgggttgg gcaacagccg gtggttccgg tttccgtggt tctcgcaaat ccactccgtt
    13141 tgcagctcag gttgcagcag agcgttgcgc tgacgccgtg aaagaatacg gcatcaagaa
    13201 tctggaagtt atggttaaag gtccgggtcc aggccgcgaa tctactattc gtgctctgaa
    13261 cgccgcaggt ttccgcatca ctaatattac tgatgtgact ccgatccctc ataacggttg
    13321 tcgtccgccg aaaaaacgtc gcgtataacg cctcgttttc caggtttgtt ggagaaagaa
    13381 aatggcaaga tatttgggtc ctaagctcaa gctgagccgt cgtgagggca ccgacttatt
    13441 ccttaagtct ggcgttcgcg cgatcgatac caagtgtaaa attgaacaag ctcctggcca
    13501 gcacggtgcg cgtaaaccgc gtctgtctga ctatggtgtg cagttgcgtg aaaagcaaaa
    13561 agttcgccgt atctatggtg tgctggagcg tcagttccgt aactactaca aagaagcagc
    13621 acgtctgaaa ggcaacaccg gtgaaaacct gttggctctg ctggaaggtc gtctggacaa
    13681 cgttgtatac cgtatgggct tcggtgccac tcgtgcagaa gcacgtcagc tggttagcca
    13741 taaagcaatt atggtaaacg gtcgtgttgt taacatcgct tcttatcagg ttagtccgaa
    13801 tgacgttgta agcattcgtg agaaagcgaa gaagcagtct cgcgtgaaag ccgctctgga
    13861 gctggctgag cagcgtgaaa agccaacctg gctggaagtt gatgctggca agatggaagg
    13921 tacgtttaag cgtaagccgg agcgttctga tctgtctgcg gacattaacg aacacctgat
    13981 cgtcgagctt tactccaagt aaagcttagt accaaagaga ggacacaatg cagggttctg
    14041 tgacagagtt tctaaaaccg cgcctggttg atatcgagca agtgagttcg acgcacgcca
    14101 aggtgaccct tgagccttta gagcgtggct ttggccatac tctgggtaac gcactgcgcc
    14161 gtattctgct ctcatcgatg ccgggttgcg cggtgaccga ggttgagatt gatggtgtac
    14221 tacatgagta cagcaccaaa gaaggcgttc aggaagatat cctggaaatc ctgctcaacc
    14281 tgaaagggct ggcggtgaga gttcagggca aagatgaagt tattcttacc ttgaataaat
    14341 ctggcattgg ccctgtgact gcagccgata tcacccacga cggtgatgtc gaaatcgtca
    14401 agccgcagca cgtgatctgc cacctgaccg atgagaacgc gtctattagc atgcgtatca
    14461 aagttcagcg cggtcgtggt tatgtgccgg cttctacccg aattcattcg gaagaagatg
    14521 agcgcccaat cggccgtctg ctggtcgacg catgctacag ccctgtggag cgtattgcct
    14581 acaatgttga agcagcgcgt gtagaacagc gtaccgacct ggacaagctg gtcatcgaaa
    14641 tggaaaccaa cggcacaatc gatcctgaag aggcgattcg tcgtgcggca accattctgg
    14701 ctgaacaact ggaagctttc gttgacttac gtgatgtacg tcagcctgaa gtgaaagaag
    14761 agaaaccaga gttcgatccg atcctgctgc gccctgttga cgatctggaa ttgactgtcc
    14821 gctctgctaa ctgccttaaa gcagaagcta tccactatat cggtgatctg gtacagcgta
    14881 ccgaggttga gctccttaaa acgcctaacc ttggtaaaaa atctcttact gagattaaag
    14941 acgtgctggc ttcccgtgga ctgtctctgg gcatgcgcct ggaaaactgg ccaccggcaa
    15001 gcatcgctga cgagtaaccg gatcacaggt taaggtttta ctgagaagga taaggtcatg
    15061 cgccatcgta agagtggtcg tcaactgaac cgcaacagca gccatcgcca ggctatgttc
    15121 cgcaatatgg caggttcact ggttcgtcat gaaatcatca agacgactct gcctaaagcg
    15181 aaagagctgc gccgcgtagt tgagccgctg attactcttg ccaagactga tagcgttgct
    15241 aatcgtcgtc tggcattcgc ccgtactcgt gataacgaga tcgtggcaaa actgtttaac
    15301 gaactgggcc cgcgtttcgc gagccgtgcc ggtggttaca ctcgtattct gaagtgtggc
    15361 ttccgtgcag gcgacaacgc gccgatggct tacatcgagc tggttgatcg ttcagagaaa
    15421 gcagaagctg ctgcagagta atctgaagca acgtaaaaaa acccgccccg gcgggttttt
    15481 ttatacccgt agcatcccca cttatctaca atagctgtac tctttttgtt catcccctgg
    15541 agtatatatg tggttacttg accagtgggc agagcgtcat atagcagaag cgcaagcgaa
    15601 aggtgagttt gataacctgg caggtagcgg cgaaccattg atactggatg atgattctca
    15661 cgtgccaccg gaattacgtg cggggtatcg cttgttgaag aatgccggtt gcttaccgcc
    15721 agaacttgag caacggaggg aagcaattca gcttctggat attctcaaag gtatccgtca
    15781 cgatgatccg caatatcaag aggttagccg tcgattgtca ttactggaat tgaagctgcg
    15841 acaagctgga ctgagtaccg attttttacg cggcgattat gctgacaagt tgttgaataa
    15901 aatcaacgat aactagtgga gtatgtatgt atcgcattgg tgagctggca aaaatggcgg
    15961 aagtaacacc cgacacgatt cgttattacg aaaaacagca gatgatggag catgaagtgc
    16021 gtactgaagg tgggtttcgc ctgtataccg aaagcgatct ccagcgattg aaatttatcc
    16081 gccatgccag acaactaggt ttcagtctgg agtcgatccg cgagttgctg tcgatccgta
    16141 tcgatcctga acaccatacc tgtcaggagt caaaaggcat tgtgcaggaa agattgcagg
    16201 aagtcgaagc acggatagcc gagttgcaga gtatgcagcg ttccttgcaa cgccttaacg
    16261 atgcctgttg tgggaccgcc catagcagtg tttattgctc gattcttgaa gctcttgaac
    16321 aaggggcgag tggcgttaag agtggctgtt gattttttgc actgacagga ttacactcgc
    16381 gccgttaaat aaccaactgg agtttttatg agccgatatc agcatactaa agggcagata
    16441 aaggataatg cgatagaagc attactacat gatcccttat tccgacagcg agtagagaaa
    16501 aataagaaag ggaaaggcag ttacatgcga aaaggaaaac atggcaatcg ggggaactgg
    16561 gaggccagtg gcaagaaagt aaatcacttt tttaccactg gccttctgct ttcaggcgtt
    16621 tgttaagagc ggttattctg ctctttcagc aaatcacgaa tttctgtcag taatacttct
    16681 tctttagttg gtgctggtgc ggctgctggt tcttcttttt tccgattcag tttgttgatt
    16741 agcttaatcg ccataaagat ggcaaaggcc acaatcagaa aatcaaagac gttttgaatg
    16801 aagacaccgt aatgcatcac aacagcaggg atatccccct gcgcatcgcg tagcgtgaca
    16861 gcaaactgtt taaagtcgat cccgccaatt aataagccca gaggtggcat gatgatatcg
    16921 gcaaccagtg aagatacaat cttcccgaat gccgcaccga taatgacacc caccgccaaa
    16981 tccaccacgt tcccgcgcat cgcaaattcg cgaaattctt taataatgct catgttattc
    17041 tccctatgaa gccgacaacc ataagtctaa caaatgttaa gccattttcc tgctaggaat
    17101 gaatttaatt aatccttgat aatcaaaggg aaataataag gcgtcattag acgccttatt
    17161 aattacaaga agaaagggct tggctggaag agtctttcga cgtcggtaat aaacttttta
    17221 tctgtgagga acataattac gtgatcgcct tgctcaatgc gcagattgtc attggcaatc
    17281 atcacgtcgt ttccacgtac caccgctcca ataatcgttc ctggcggtag cttgatttcg
    17341 tcaatgactc tgccgacaac gcgtgaggtg ctttcatcac cgtgagcaac ggcttcaata
    17401 gcttctgcta cgccgcggcg caatgaggaa acaccaacaa tatctgcttt tcgcacatgg
    17461 ctaagcaacg cagaaatagt tgcttgttgt ggtgaaatcg caatatcgat cacgctcccc
    17521 tgaaccagat ccacataagc gcgacgctgg atcaatacca tcaccttttt cgcacccata
    17581 cgtttggcaa gcatggcgga catgatattg gcctcgtcat cgttggtgac ggcaataaac
    17641 agatcaactt gatcgatatg ttcttcggcc agcagttctt gatccgacgc atcaccaaaa
    17701 aagacgatcg tattctgcaa cttttccgcc agttcggcag cgcgctgctg attacgttcg
    17761 atgagtttaa cgctgtaatc tttttccaga cgacgcgcca gccctgcacc gatattaccg
    17821 ccaccaacca gcatgatccg cttatacggt ttttccagtc gctgtaattc actcatcacc
    17881 gcacggatat gctgtgaagc ggcaataaag aacacttcat caccagcttc cacaatggtc
    17941 gaaccttgtg gacgaatggg gcgatcgtgg cggaaaattg ctgccacacg agtatcgata
    18001 tgtggcatat gttcgcgcat ggtcgaaagt gcgttaccaa tcagcgggcc gccataatag
    18061 gctttaacca cagcgaggct gactttaccc tcagcgaagt tcaccacctg caatgcgccg
    18121 ggatactcaa tcagtcggta aatattatcg ataaccaact gctctggtgc gatcagatga
    18181 tcaatcggta cagcatctga atgaaatagc ttatcggcat cgcgcacgta gtctggtgag
    18241 cggatgcgag cgatgcgatt aggggtgttg aaaagtgagt aggctacctg gcaggcaacc
    18301 atattggttt catctgaact ggttacagca accagcatat cggcgtcgtc ggcacctgcc
    18361 tcccgcaata cgcgtggatg agagccatgc ccctgcacga ctcgcaggtc aaatttatcc
    18421 tgcaaggtcc gcagacgctc accgttggta tcgacaacag tgatatcgtt gttctcgcca
    18481 accaggtttt ccgccagtgt gccgccaacc tggccggcac ccagaatgat aattttcatc
    18541 agtcgcgacc cgttatctca tcactttttg attagcttag cgtaaaagaa gccgtcgccc
    18601 tcttcggcac caggcagatt ttgtttaccc ggttgctctg gtgttcctgt ttcgcaaagt
    18661 tcggcatcag cggtacgttg caaaaaggct ttaatctgca ggctattctc ttccggtaac
    18721 accgaacagg tggcatagac cagggttcca ccggatttta aatgcggcca aatggcgtcg
    18781 agaatttcag actgcaattg cgcgagttcc gggatatcgc gatcgcgacg taaccattta
    18841 atatccggat ggcgacgaat cacaccggtt gctgaacaag gcgcatctaa taaaatgcga
    18901 tcaaactgtt gctcgccaca ccattgggaa gggtagcggc catcaccttg tttcacggtc
    18961 gctttcatac caaggcgttt taaattgtcg taaacgcgag agaggcgctg ttcgtcaata
    19021 tcaaccgcaa caacctgcgc ttctggtgcc acctcaagga tatgcgttgt tttaccgccg
    19081 ggggcggcac aaagatccag aatgtgttca ccgttttgtg gcgcaagcca ggtcatgcaa
    19141 ccttgtgctg atgcatcctg aacggtaacc catccgtctt caaaaccagg tagcgcatga
    19201 acaggtgcag gtgtttccag ccgtacagca tcagggtaat ccgcatgcgg gaaacctttc
    19261 attcctgctt catccaacaa tgcaagccag ctgtcgcggg aatgatgcgt acgattaacg
    19321 cgcagccaca ttggcggacg ctggttattg gcttcgacga tggattgcca ctgctctgga
    19381 tacgcttttt gcagacgctt cagcaaccag gaaggatgca gataacgtgc atcactggca
    19441 ttaaactcgg ctaataactc ttcttgctga cgctggaact ggcgtaatac accgtttatc
    19501 aaccctttaa gttgcggacg cttaattgcg atagcgcctt caaccgtttc agccagcgca
    19561 gcatgaggtg gaatgcgggt ataaagcagt tgatacaaac caaccataat caggtaatgc
    19621 acggtccgct gtttgccggt catcggacgg gccattaact tattaatcag ccagtctaac
    19681 tgcgaaagcg tacgcagtac gccaaagcac aactcttgaa gaagtgcttt gtctttatcg
    19741 gaaacttttt gctggagcgg tggcagaatg ttgcttaatg attgcccttg ctcgacgact
    19801 tgttcaacgg cctgggccgc catgctacgt aaattacgtt gttttttcat aagtataaaa
    19861 acgcccggca agaccgggct tagaagagtg gactatcaga ccagacggtt gcccggaaca
    19921 aaccattccc gacgagagtt caggaggtct tgcgcgctca tcgctttctt acccgcaggt
    19981 tgtaacgaga gcaggttcag gatgccatca ccagtcgcaa cctgaatgcc ttgtttgttg
    20041 gcttcaagga tcgttcctgg tgcagcgttg gttgccgtat caatgaccga tgctttccag
    20101 actttaaccg gctgtccttc aatttccagc cagctcattg gccatggatt gaaagcgcga
    20161 atgcagcgtt caagctgtgc tgccgaaagt gaccagtcaa tacgcgcttc ttctttactc
    20221 aacttttcgg cgtaagtgac aagagtttcg tcctgaactt ctggtttcgc cgtgccgtct
    20281 gccagttgtt tcaacgtggt gataagccct tgtgggccaa gctctgccag cttgtcgtac
    20341 agcgtaccac tggtatcttc tgcagtaatc gggcaggaga gcttatagag catgtcaccg
    20401 gtgtctaaac cgacatccat ttgcataatg gtcacaccag tttctgcatc acccgcccat
    20461 agtgagcgtt ggattggtgc agcaccgcgc cagcgtggca gcagtgaacc atgaacgttg
    20521 atacagccaa gacgcggcat ctccagcact gctttaggca gaattaagcc ataggcgacg
    20581 acgaccataa catcagcctg cagatcggcg accagttgct ggttttcttg tggacgcagg
    20641 gaaacaggtt gaaaaacggg cagacctttt tcctcagcca gaactttaac cgggctgggc
    20701 atcagttttt taccgcgtcc tgccggtcgg tctggctggg tgaacacgcc aacgacgtta
    20761 tgaccagaag acaacagcgc gtcgagatga cgcgctgcaa agtcaggtgt acccgcaaaa
    20821 ataatacgta gtgattctga cacgttagtt cttatcctta agcccgggct ttcagacgat
    20881 ccagtttttc aactttctga cgaatacgtt gttgtttcaa cggtgacaga taatccataa
    20941 acagtttgcc gaccaggtga tccatctcat gctgaataca gatggctaac agaccgtctg
    21001 cttccaattc aaatggttta ccgtcgcggt ccagggcgcg aattttaact ttctctgcgc
    21061 gtggcactaa agcacgttgt tcagggatcg acaggcaacc ttcttcaatg cctgtttcgc
    21121 cgcttttttc taaaagctcc ggattgatta acaccagccg ttcgtcacgg ttttccgaaa
    21181 catcaataac aatgatacgt tgatggatat caacctgggt tgccgccagg ccaatacctt
    21241 cttctgcgta catcgtctcg aacatatcat cgacgatacg ctgaatttct gcattcactt
    21301 cttctaccgg tttagcaact ttgcgaagcc gctcgtccgg aatatgtaac acttgcaaaa
    21361 ctgacataaa tctccagaga tgtgttcagg agttagaaag attatttctt ctattctaga
    21421 caaatccccc tctgattgac agcatcactg accaatcgca aagattgcta aggctgctta
    21481 tggcagggag ataaggatgg tcgatacaga aatttggctg cgtttaatga gtatcagcag
    21541 cttgtacggc gatgatatgg tccgtatagc tcactggctg gcaaaacagt cgcaaattga
    21601 tgcggttgga ttgcagcaaa cagggcttac attgcggcag gcacaacgct ttctttcatt
    21661 tccgcgaaag agtatcgaaa gctcactttg ttggttggag caacccaacc atcatttaat
    21721 ccctgcggac agcgaatttt atcctcctca acttcaggcg acgacagatt accccggcgc
    21781 actgtttgtt gaaggagaac tgcacgcgct gcattcattt cagcttgcca tagtggggag
    21841 tcgggcgcat tcatggtatg gcgagcgatg gggacgatta ttttgcgaaa ctctggcgac
    21901 gcgtggagtg acaattacaa gtggactggc gcgtggaatc gatggtgtgg cgcataaagc
    21961 ggccttacag gtaaatggcg tcagcattgc tgtattgggg aatggactta ataccattca
    22021 tccccgccgc catgcccgac tggctgccag tttgcttgaa catggcggag ctctcgtctc
    22081 ggaatttccc ctcgatgttc caccccttgc ttacaatttc ccacgaagaa atcgcattat
    22141 cagtggtcta agtaaaggtg tactggtggt ggaagcggct ttgcgcagtg gttcgctagt
    22201 gacagcacgt tgtgcgcttg agcaggggcg tgaagttttt gccttgccag gtccaatagg
    22261 gaatccggga agcgaagggc ctcactggtt aataaaacaa ggtgcgattc ttgtgacgga
    22321 accggaagaa attctggaaa acttgcaatt tggattgcac tggttgccag acgcccctga
    22381 aaattcattt tattcaccag atcagcaaga cgtggcattg ccatttcctg agctcctggc
    22441 taacgtagga gatgaggtaa cacctgttga cgtcgtcgct gaacgtgccg gccaacctgt
    22501 gccagaggta gttactcaac tactcgaact ggagttagca ggatggatcg cagctgtacc
    22561 cggcggctat gtccgattga ggagggcatg ccatgttcga cgtactaatg tatttgtttg
    22621 aaacctatat tcacacagaa gctgagttgc gtgtggatca agacaaactt gaacaggatc
    22681 ttaccgacgc aggatttgat cgagaagata tttacaatgc cctgctttgg ctggaaaagc
    22741 ttgcggatta tcaggaagga ctggcagaac cgatgcaact ggcctctgat ccactctcca
    22801 tgcgtattta tacccctgag gagtgtgaaa gactggatgc cagctgtcgt ggttttctgc
    22861 ttttccttga gcagattcag gtgctcaacc ttgaaactcg tgaaatggtg atagagcgag
    22921 tgctcgcgct ggataacgca gagttcgaac tggatgatct gaaatgggta atcctgatgg
    22981 tgttgttcaa tattccgggc tgcgaaaatg cgtaccagca aatggaagaa ttactctttg
    23041 aagtgaatga aggtatgctg cattaatcat ttctttaatt cagcataagt tgttatggcg
    23101 aaatcagcac tgttcacggt gcgtaataat gagtcctgcc caaagtgcgg ggctgaactg
    23161 gttattcgat ccgggaaaca cggtccgttt cttggatgct cacagtatcc ggcgtgtgac
    23221 tacgtccgtc ctctgaaatc ttcagcggat ggacatattg tcaaagttct ggaggggcag
    23281 gtttgccctg catgtggcga aaatctggta ttacgccagg gacgctttgg tatgtttatt
    23341 ggttgcagta actaccctga atgcgaacat accgaactta tcgataaacc ggacgaaaca
    23401 gcaattacat gcccccaatg ccggacgggc catctggtcc agcgccgctc ccgttatggc
    23461 aaaacatttc actcctgtga tcgctacccg gagtgtcaat ttgccattaa cttcaaaccc
    23521 atagctggag aatgccctga gtgtcattat ccactactca tcgaaaagaa aaccgcgcag
    23581 ggtgtaaaac acttttgtgc cagtaaacaa tgtggaaagc cggtttcggc ggaataataa
    23641 cgtgaataat aacctgcaag gagacgctat cgcagctgcg atagatgtcc tcaatgaaga
    23701 acgtgtcatc gcctatccaa cggaagccgt tttcggtgtc gggtgcgatc ctgatagcga
    23761 aacagcagtg atgcgactgt tggagttaaa acagcgtccg gttgataagg ggctgatttt
    23821 aatcgcggca aattacgagc agcttaaacc ctatattgat gacaccatgc tgactgatgc
    23881 gcagcgtgaa accatttttt cccgctggcc aggtcctgtc acctttgtct ttcccgcgcc
    23941 tgcgacaaca ccgcgctggt tgacgggccg ctttgattcg cttgctgtac gagtcaccga
    24001 ccatccgttg gtggttgctt tgtgccaggc ttatggtaaa ccgctggttt ctaccagtgc
    24061 caacttgagt ggattgccac cttgtcgaac agtagacgaa gttcgcgcac aatttggcgc
    24121 ggcgttcccg gttgtgcctg gtgaaacggg ggggcgttta aatccttcag aaatccgcga
    24181 tgccctgacg ggtgaactgt ttcgacaggg gtaacataat ggaaacctat gctgtttttg
    24241 gtaatccgat agcccacagc aaatcgccat tcattcatca gcaatttgct caacaactga
    24301 atattgaaca tccctatggg cgcgtgttgg cacccatcaa tgatttcatc aacacactga
    24361 acgctttctt tagtgctggt ggtaaaggtg cgaatgtgac ggtacctttt aaagaagagg
    24421 cttttgccag agcggatgag cttactgaac gggcagcgtt ggctggtgct gttaataccc
    24481 tcaagcggtt agaagatgga cgcttgcagg gtgacaatac cgatggtata ggtttgttaa
    24541 gcgatctgga acgtctgtct tttatccgtc cgggtttacg tattctgctt atcggcgctg
    24601 gtggagcatc tcgcggcgta ctactaccac tcctttccct ggactgtgcg gtgacaatca
    24661 ctaatcggac ggtatcccgc gcggaagagt tggctaaatt gtttgcgcac actggcagta
    24721 ttcaggcgtt gggtatggac gaactggaag gtcatgagtt tgatctcatt attaatgcaa
    24781 catccagtgg catcagtggt gatattccgg cgatcccgtc atctctcatt catccaggca
    24841 tttattgcta tgacatgttc tatcagaaag gaaaaactcc ttttctggca tggtgtgagc
    24901 agcgaggctc aaagcgtaat gctgatggtt taggaatgct ggtggcacag gcggctcatg
    24961 cctttcttct ctggcacggt gttctgcctg acgtagaacc agttataaag caattgcagg
    25021 aggaattgtc cgcgtgaatc aggccatcca gtttccggac agagaagagt gggacgagaa
    25081 taaaaaatgt gtatgttttc ccgctctcgt gaatggcatg caactgacat gtgcgatctc
    25141 tggcgagagt ctggcgtatc gttttactgg agatacgcca gaacagtggt tagcgagttt
    25201 tcgtcagcat cgctgggatc tggaagaaga agcggaaaac ttaattcagg aacaaagtga
    25261 agatgatcaa ggctgggtct ggttaccctg atccagatat tcgtccttcc atttcacgta
    25321 attattcgcg gaatagcgta acccagcctt ctcttcatca cttaacgggc ggatctgttt
    25381 gacggggcta ccgagataca gatatccgct ctccagccgt ttattttgtg ggaccagact
    25441 acccgcacca atcatcacat catcttctac tattgcgcca tcaagtaaaa ttgagcccat
    25501 cccaaccaaa actcgattgc caatggtgca gccgtggagc atcaccttgt gaccaacagt
    25561 gacatcttcg ccaatggtta atgggttgcc atctgggttg tacgaggatt tatgagtgac
    25621 atgcaacata ctgccatcct ggatattggt gcgtgctccg atctgtacat aatgtacatc
    25681 tccacgaatc acaacgagcg gccagatccc cacatcatca gccagacgaa cgtcaccaat
    25741 cacgacactg ctatcgtcga tcattacgcg ctgaccgatt tgtggaaaaa gatcgcggta
    25801 tgggcgtaaa acatcagaca tacttacctc agcaataaat gatttactaa tgactttggg
    25861 ggcattattg gccttgtgca agtcttttag tatgcaaaaa agcaccgttt tgtgtgcgat
    25921 tgcagcaaaa agggtgaaaa aacaacaaac agaaaaaaag atcaaaaaaa tacttgtgca
    25981 aaaaattggg atccctataa tgcgcctccg ttgagacgac aacgtgaaac acttcacagg
    26041 atggtcggaa caacgaagag aaaaaatcct gaaatt
//
LOCUS       DAZUDJ010000067        25747 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.067, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000067 DAZUDJ010000000
VERSION     DAZUDJ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25747
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.067"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..525)
                     /locus_tag="ACHY1N_003762"
     CDS             complement(<1..525)
                     /locus_tag="ACHY1N_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YPO3983 family protein"
                     /protein_id="HFS4045983.1"
                     /translation="MNNILLPPINIPCTLFETISLFDDFSADDMQYGDMVEQDFLSLG
                     LSDISAKVDPYRLIKYHFPGPGSINVAFSASSSGTKISQRECTDILFAEMKELAKMFS
                     FFGQNKTLIEDLIEHFRYGNGSNFHSQQLNLSFHEKINKYGYNSPIRIIKECIENGIN
                     STPSTGYQPLILQSI"
     gene            706..858
                     /locus_tag="ACHY1N_003763"
                     /pseudo
     CDS             706..858
                     /locus_tag="ACHY1N_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
     gene            1480..1779
                     /locus_tag="ACHY1N_003764"
     CDS             1480..1779
                     /locus_tag="ACHY1N_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4045984.1"
                     /translation="MGNGNFWQLFLGKEPYSKKSDFVKAWLLWWAITILALFILSLTT
                     TLNLRSIGIGLSFGFCQILGRYTMSLGWSKYWGVLGVFPVTNIVLFLILIFFKKR"
     gene            complement(1826..2713)
                     /gene="rarD"
                     /locus_tag="ACHY1N_003765"
     CDS             complement(1826..2713)
                     /gene="rarD"
                     /locus_tag="ACHY1N_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HFS4045985.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVVLMSICRQWSYLKTLIQTPQKIFMLAVSAVLIGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNIVLGMIFLGERFRRMQWLAVILAICGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLIETMWLLPVAAIYLFAIADSSTSHMGQNPMSLNLLLIA
                     AGIVTTVPLLCFTAAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEKPGADKMVTFAFI
                     WVALAIFVMDAIYTQRRKS"
     gene            complement(2765..3232)
                     /gene="yigI"
                     /locus_tag="ACHY1N_003766"
     CDS             complement(2765..3232)
                     /gene="yigI"
                     /locus_tag="ACHY1N_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase YigI"
                     /protein_id="HFS4045986.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGMELERYEKEFAQLAF
                     KNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGERFTATSSLLRAGNKVAVARVELHNEEQLYIASATATYMVG"
     gene            3397..4266
                     /gene="pldA"
                     /locus_tag="ACHY1N_003767"
     CDS             3397..4266
                     /gene="pldA"
                     /locus_tag="ACHY1N_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004620 - phospholipase activity [Evidence
                     IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HFS4045987.1"
                     /translation="MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLK
                     IGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDLF"
     gene            4399..6228
                     /gene="recQ"
                     /locus_tag="ACHY1N_003768"
     CDS             4399..6228
                     /gene="recQ"
                     /locus_tag="ACHY1N_003768"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFS4045988.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCL
                     VVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTRE
                     QQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRA
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFSEG
                     RQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDY
                     GHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSL
                     QLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEM
                     AEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE"
     gene            6292..6912
                     /gene="rhtC"
                     /locus_tag="ACHY1N_003769"
     CDS             6292..6912
                     /gene="rhtC"
                     /locus_tag="ACHY1N_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HFS4045989.1"
                     /translation="MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEAVSAP
                     APQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVET
                     LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(6974..7594)
                     /gene="rhtB"
                     /locus_tag="ACHY1N_003770"
     CDS             complement(6974..7594)
                     /gene="rhtB"
                     /locus_tag="ACHY1N_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HFS4045990.1"
                     /translation="MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIA
                     GLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSL
                     ASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDII
                     VMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA"
     gene            7705..8727
                     /gene="pldB"
                     /locus_tag="ACHY1N_003771"
     CDS             7705..8727
                     /gene="pldB"
                     /locus_tag="ACHY1N_003771"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HFS4045991.1"
                     /translation="MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVR
                     FVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHLGFDVLIIDHRGQGRSGRLLADP
                     HLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIA
                     LTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRY
                     RRNLRFYADDPTIRVGGPTYHWVRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNR
                     MHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSG
                     NRSTEV"
     gene            8735..9535
                     /gene="yigL"
                     /locus_tag="ACHY1N_003772"
     CDS             8735..9535
                     /gene="yigL"
                     /locus_tag="ACHY1N_003772"
                     /EC_number="3.1.3.23"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HFS4045992.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII
                     TNVYRDDEWFMNRHRPEEMRFFKEAVFKYALYEPGLLEPEGVSKVFFTCDSHEQLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND
                     AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS"
     gene            9611..10510
                     /gene="bioP"
                     /locus_tag="ACHY1N_003773"
     CDS             9611..10510
                     /gene="bioP"
                     /locus_tag="ACHY1N_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter"
                     /protein_id="HFS4045993.1"
                     /translation="MALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFL
                     PFLRTRGNSLKTVGLYMLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIY
                     DIMSKRRLRWGYAFSALLAVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVH
                     RKWVAPRSSQTADDRRRDCALSE"
     gene            complement(10398..11351)
                     /gene="metR"
                     /locus_tag="ACHY1N_003774"
     CDS             complement(10398..11351)
                     /gene="metR"
                     /locus_tag="ACHY1N_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HFS4045994.1"
                     /translation="MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     YEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQP
                     VTEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL"
     gene            11474..13735
                     /gene="metE"
                     /locus_tag="ACHY1N_003775"
     CDS             11474..13735
                     /gene="metE"
                     /locus_tag="ACHY1N_003775"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFS4045995.1"
                     /translation="MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLTVGRELR
                     ARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHNVKPV
                     LLGPVTYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELP
                     QAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAEL
                     HKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSV
                     ETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAV
                     EKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKG
                     NLDANNYRTGIAEHIRQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEA
                     FRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAAL
                     ANMVQAAQNLRLG"
     gene            complement(13774..14589)
                     /gene="ysgA"
                     /locus_tag="ACHY1N_003776"
     CDS             complement(13774..14589)
                     /gene="ysgA"
                     /locus_tag="ACHY1N_003776"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HFS4045996.1"
                     /translation="MATTQQSGFAPAASPLASTIVQTPDDAIVAGFTSIPSQGDNMPA
                     YHARPKQSDGPLPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDVHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLTGDKSLNSPKQPVDIATDLNAPVLGLYGGQDNSIPQESVETMRQA
                     LRAANAKAEIIVYPDAGHAFNADYRPSYHAESAKDGWQRMLEWFKQYGGKKSL"
     gene            14851..15612
                     /gene="udp"
                     /locus_tag="ACHY1N_003777"
     CDS             14851..15612
                     /gene="udp"
                     /locus_tag="ACHY1N_003777"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HFS4045997.1"
                     /translation="MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKL
                     ASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESQAVKIVVEAARRLL"
     gene            15753..17180
                     /gene="rmuC"
                     /locus_tag="ACHY1N_003778"
     CDS             15753..17180
                     /gene="rmuC"
                     /locus_tag="ACHY1N_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HFS4045998.1"
                     /translation="MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAE
                     LSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR
                     QMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSF
                     GKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASG
                     LREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTR
                     ESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPAFLLALDRQPELITE
                     ALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFIDDMSAI
                     GQSLDKAQDNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEY
                     RLRSVPEQPNDEAYQRDDEYNQQSR"
     gene            17275..18030
                     /gene="ubiE"
                     /locus_tag="ACHY1N_003779"
     CDS             17275..18030
                     /gene="ubiE"
                     /locus_tag="ACHY1N_003779"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HFS4045999.1"
                     /translation="MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQ
                     DTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            18044..18649
                     /gene="ubiJ"
                     /locus_tag="ACHY1N_003780"
     CDS             18044..18649
                     /gene="ubiJ"
                     /locus_tag="ACHY1N_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HFS4046000.1"
                     /translation="MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGF
                     STSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLTALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKAMRGGAKFLHHGIKRQQRYVAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK"
     gene            18646..20286
                     /gene="ubiB"
                     /locus_tag="ACHY1N_003781"
     CDS             18646..20286
                     /gene="ubiB"
                     /locus_tag="ACHY1N_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HFS4046001.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWM
                     PNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDG
                     KLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFF
                     TQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAF
                     KEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGAT
                     LVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR"
     gene            20365..20634
                     /gene="tatA"
                     /locus_tag="ACHY1N_003782"
     CDS             20365..20634
                     /gene="tatA"
                     /locus_tag="ACHY1N_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HFS4046002.1"
                     /translation="MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV"
     gene            20638..21153
                     /gene="tatB"
                     /locus_tag="ACHY1N_003783"
     CDS             20638..21153
                     /gene="tatB"
                     /locus_tag="ACHY1N_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008320 - protein transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase protein
                     TatB"
                     /protein_id="HFS4046003.1"
                     /translation="MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPE
                     KASDEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKT
                     AAPSPSSSDKP"
     gene            21156..21932
                     /gene="tatC"
                     /locus_tag="ACHY1N_003784"
     CDS             21156..21932
                     /gene="tatC"
                     /locus_tag="ACHY1N_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HFS4046004.1"
                     /translation="MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHL
                     VSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFFSRFYVGKGRNREEENDAEAESEKTEE"
     gene            21974..22756
                     /gene="tatD"
                     /locus_tag="ACHY1N_003785"
     CDS             21974..22756
                     /gene="tatD"
                     /locus_tag="ACHY1N_003785"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HFS4046005.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVARAFDAGVNGLLITGTNLRESQQ
                     AQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFST
                     PEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREE
                     MQACVARGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSS
                     RRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF"
     gene            complement(22753..23241)
                     /gene="rfaH"
                     /locus_tag="ACHY1N_003786"
     CDS             complement(22753..23241)
                     /gene="rfaH"
                     /locus_tag="ACHY1N_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HFS4046006.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRT
                     AVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPK
                     DIVDPATPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFR
                     KL"
     gene            23408..24901
                     /gene="ubiD"
                     /locus_tag="ACHY1N_003787"
     CDS             23408..24901
                     /gene="ubiD"
                     /locus_tag="ACHY1N_003787"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HFS4046007.1"
                     /translation="MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGY
                     IEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA"
     gene            24947..25648
                     /gene="fre"
                     /locus_tag="ACHY1N_003788"
     CDS             24947..25648
                     /gene="fre"
                     /locus_tag="ACHY1N_003788"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HFS4046008.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDE
                     ERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHP
                     GLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSER
                     NAREDRLFGDAFAFI"
BASE COUNT         6184 a         6264 c         6920 g         6379 t
ORIGIN      
        1 aatgctttgc aggataagag gttggtatcc tgtcgaggga gttgaattaa tgccattttc
       61 gatacattct ttgattattc gtattggact attataacca tatttattta ttttttcatg
      121 aaaagataaa tttaattgtt ggctatgaaa attgctgcca tttccatatc taaaatgttc
      181 aatcagatct tcgataagtg ttttattttg tccaaaaaag gaaaacattt ttgctagttc
      241 tttcatttct gcaaataaaa tatcagtgca ttcacgttgt gatatttttg ttccggaact
      301 tgaggcacta aaagcaacat taatagaacc tgggccaggg aaatggtatt taataagtct
      361 gtaaggatca acttttgctg agatatcgct taggccgagt gagagaaagt cttgttctac
      421 catatcacca tattgcatat catcagcaga aaaatcatcg aataaactaa tagtttcgaa
      481 aagtgtacag ggaatattaa ttggcggaag taatatgtta ttcatttgca tttgccttgg
      541 ttatatttaa gctcaatatc aattcgagaa caaatgctag ggtaaaaaaa tatttaaaaa
      601 agaagtaaac ttcacatttt ttcattacat ctctgaagag aacctcgtta atgattggtc
      661 ttgctcattg ttaataacaa aatgttgaat ttaccgatta ggaaactttt tcctacgcgg
      721 attgcctcca gctatggcat gaactttgag tttatgccag aactgaagtg gggcttcggc
      781 taccctggcg cgattatctt tatgatcctc gcgggcctga catcgtatct gtactttaag
      841 cgtaagaact ggctgtaact atacgatgtc gctgtgagta agttagtgtg ctgacagcga
      901 cattttagcc gagggaatcg cagataacat aattgttgtg aataatatcc atgccacgtt
      961 gagttggacg cttaatgact cacatctcac cccttcaatt gctgcagaga taatagaaaa
     1021 aagtgtcaag cccaatgaaa tcaatacaaa gtagattgcc ttacatccag tatctcttat
     1081 tctttttgct ccaatattga tatttacata ggtattatta ataaccagaa taaaactcaa
     1141 agccaggttg atatcattca aagttattaa tattgaccat gatgttaatg tatagattat
     1201 gaactgaaag cgtgataaac gctcaagcct ggatgggtag aatatatttc tgatggatga
     1261 tttgaacatt tttacattgt tttatatata attgttttga atatatatta cctgaattat
     1321 gtggtttgca tatatatgca atatagcagt ctttgcattg ataactatac agtagtaatt
     1381 tagagtgtgt aagtttttat tgatggggta tattttaatt aaatataatt gaaatgtatt
     1441 tttattctat aaacaatatc ttgggtgaat ggattctata tgggaaatgg taacttttgg
     1501 cagttgttct tgggtaaaga accttacagc aaaaaatctg attttgttaa ggcatggtta
     1561 ttgtggtggg ctattaccat ccttgctcta tttattttaa gcctgactac gacattaaat
     1621 ttaagaagta taggtatagg gttaagtttt gggttttgtc aaatccttgg tagatatacg
     1681 atgtctctag gatggagtaa gtactgggga gttttggggg tatttcctgt aacaaatatt
     1741 gttctttttc ttatcttaat ttttttcaaa aaaagataaa taagtcagtg ggtaggctct
     1801 ttaaacggcc tacccatgtt aattcttaac tttttctacg ctgcgtataa atcgcatcca
     1861 tcacaaaaat tgccagcgcc acccaaataa aggcgaaagt caccatctta tcggcacccg
     1921 gtttttcacc ataaaacgtc acagccagca ggaacatcag cgtcgggcca atgtactgga
     1981 aaaagcctaa cgttgagaga cgcaagcgcg tggcagcggc ggtaaaacac aacagcggta
     2041 cggtagtgac aataccggcg gcgatcagca gtaaattcag cgacatcggg ttttgcccca
     2101 tatggctggt tgagctgtcg gcaatagcaa acaggtaaat tgccgccacg ggcagcagcc
     2161 acatggtttc gattaacatg ccggtttgcg cttcaacggc aatcttcttg cgtaccagac
     2221 cgtagaaggc aaaactaaat gccagtccca gcgcgataat aggtagcgaa ccaaaagtcc
     2281 acagctggac taacacgcca catatcgcca gaatcaccgc cagccattgc atccggcgga
     2341 atcgctcgcc gaggaaaatc atccccagca caatgttcac cagcgggtta ataaagtaac
     2401 caaggctcgc ttccagcata tggtgattgt tcaccgccca gataaacagt agccagttgc
     2461 caccaatcag cacggcagag actgccagca taaaaatttt ctgtggcgtc tgaatcagcg
     2521 tttttaaata ggaccactgg cggcaaatgc tcatcagcac caccataaag aaaaacgacc
     2581 agatcacgcg atgcgtcagg atttcatcgg caggcacgta gtaaatcaac ttgaagtacg
     2641 ctggcgctat accccaaata aaataagcgg caagagcgag taatacgccc tgccgcgttt
     2701 gttttgcatc catcgggaat actcattttt aattggtaac agcagtttac ctgcttttat
     2761 gtcttcaacc taccatatag gtggcggtgg cactggcaat ataaagctgt tcttcattgt
     2821 gtaattcaac gcgggcgacg gcgactttat tgcctgcacg caacaggcta ctggtagcag
     2881 taaaacgctc gcccctgcct gggcgcagat aatcaacgcg aagatcaatg gtccccatcc
     2941 gcgatagccg ctggcgtagt tcatcttcac tgatggtttc gtggcgggtt aaggtacttc
     3001 ccacgcacac cagaccggcg gcgacatcca gcgccgacgc aatgaccccg ccgtgcaaaa
     3061 tgctttgcgc ccagttgccc accatcattg gctgattttt aaaggccagc tgtgcgaact
     3121 ctttttcgta acgctccagt tccatcccca atgcgcggtt aaatggcatg tgataaacaa
     3181 acatctcacc cactaatttc agggcttgtt cagcggtcag tacggcagac atatcatcct
     3241 tacacttcat tggttaatga aatgttgatt ttatgcttct ttgttgttgg tttctacttt
     3301 aggaagggat aactaacggc tatggagtta agtatgtaaa atagcccgca gaaaaatatt
     3361 caccttatca ataattcgtt acggagaaca cgaccgatgc ggactctgca gggctggttg
     3421 ttgccggtgt ttatgttgcc tatggcagta tatgcacaag aggcaacggt gaaagaggtg
     3481 catgacgcgc cagcggtgcg tggcagtatt atcgccaata tgctgcagga gcatgacaat
     3541 ccgttcacgc tctatcctta tgacaccaac tacctcattt acacccaaac cagcgatctg
     3601 aataaagaag cgattgccag ttacgactgg gcggaaaatg cgcgtaagga tgaagtaaag
     3661 tttcagttga gcctggcatt tccgctgtgg cgtgggattt taggcccgaa ctcggtgttg
     3721 ggtgcgtctt atacgcaaaa atcctggtgg caactgtcca atagcgaaga gtcttcaccg
     3781 tttcgtgaaa ccaactacga accgcaattg ttcctcggtt ttgccaccga ttaccgtttt
     3841 gcaggttgga cgctgcgcga tgtggagatg gggtataacc acgactctaa cgggcgttcc
     3901 gacccgacct cccgcagctg gaaccgcctt tatactcgcc tgatggcaga aaacggtaac
     3961 tggctggtag aagtgaagcc gtggtatgtg gtgggtaata ctgacgataa cccggatatc
     4021 accaaatata tgggttacta ccagcttaaa atcggctatc acctcggtga tgcggtgctc
     4081 agtgcgaaag gacagtacaa ctggaacacc ggctacggcg gcgcggagtt aggcttaagt
     4141 tacccgatca ccaaacatgt gcgcctttat actcaggttt acagcggcta tggcgaatcg
     4201 ctcatcgact ataacttcaa ccagacccgt gtcggtgtgg gggttatgct aaacgatttg
     4261 ttttgatgaa cggttgagtg gttggcaaat ctggaatcca gcatccagga ttaccctctc
     4321 agagactaaa agcattgcag tttctcgcgc aggcgctgaa aatagcgcct gtttttattt
     4381 caggcaatcg gggtgaatgt ggcgcaggcg gaagtgttga atctggagtc cggagctaaa
     4441 caggttttac aagaaacctt tggctaccaa cagtttcgcc ccggccagga agaaattatc
     4501 gacactgtgc tttccggtcg cgattgcctg gtcgtcatgc ccaccggtgg cggaaaatcc
     4561 ctttgctatc aaattcctgc cttattgcta aacggcctta ccgtggttgt ttcaccgctg
     4621 atttcgttga tgaaagatca ggtggatcaa ctgcaagcca acggcgtggc ggcggcgtgc
     4681 cttaactcga cgcaaacccg cgaacagcaa cttgaagtga tgacaggctg ccgcaccggg
     4741 caaattcgtc tgctttatat cgccccggaa cgcctgatgc tggataactt tcttgagcat
     4801 ctggcgcact ggaatccggt gttattagcc gttgatgaag cgcactgtat ctcccaatgg
     4861 ggccacgatt tccgcccgga atatgccgcg ctcggtcagt tgcgccagcg gttcccgacg
     4921 ctgccgttta tggcgctgac cgccacagcc gacgacacca cgcgccagga tatcgtgcgc
     4981 ctgctggggc tgaacgatcc gctgattcaa atcagcagtt ttgaccgtcc gaatattcgc
     5041 tacatgctga tggagaagtt caaaccgctc gatcagttga tgcgctacgt gcaggaacag
     5101 cgcggtaagt ccggcattat ctactgcaac agccgggcga aagtagaaga caccgctgcg
     5161 cgcctgcaaa gcaagggtat tagcgcggcg gcctatcatg ccgggctgga aaataatgtc
     5221 cgcgccgacg tgcaggagaa attccagcgc gatgacctgc aaattgtggt ggcgacggtg
     5281 gcgttcggca tgggcatcaa taaaccaaac gttcgcttcg tggtccactt tgatattccg
     5341 cgcaatatcg aatcctatta tcaggaaacc ggtcgcgccg ggcgtgatgg cctgcccgcg
     5401 gaagcgatgc tgttttacga tccggccgat atggcgtggc tgcgccgttg tctggaagag
     5461 aagccgcagg ggcagttgca ggatatcgaa cgtcataaac tcaatgcgat gggcgctttt
     5521 gccgaagcgc aaacttgccg tcgtctggta ctgctgaact attttagcga agggcgtcag
     5581 gagccgtgcg ggaactgcga tatctgcctc gatccgccga aacagtacga cggttcaacc
     5641 gatgctcaga ttgccctttc caccattggt cgtgtgaatc agcgttttgg tatgggctat
     5701 gtggtggaag tgattcgcgg cgctaataac cagcgtatcc gcgactatgg tcatgacaaa
     5761 ctaaaagtct acggtatggg ccgtgataaa agtcatgaac attgggtgag cgtgatccgc
     5821 cagttgattc acctcggcct ggtgacgcaa aatattgccc agcattctgc cctccaactg
     5881 acagaggccg cgcgtccggt gctgcgcggc gaatcctctt tgcaacttgc cgtgccgcgt
     5941 atcgtggcgc tcaaaccgaa agcgatgcag aaatcgttcg gcggcaacta tgatcgcaaa
     6001 ctgttcgcca aattacgcaa actgcgtaaa tcgattgccg atgaaagcaa tgtcccgccg
     6061 tacgtggtgt ttaacgacgc aacgttgatt gagatggctg aacagatgcc gatcaccgcc
     6121 agcgaaatgc tcagcgttaa cggcgttggg atgcgcaagc tggaacgctt tggtaaaccg
     6181 tttatggcgc ttatccgcgc gcatgttgac ggcgacgacg aagagtagtc agcggcataa
     6241 aaaagtgcca ggatgaagac tccgtaaacg tttcccccac gagtcaaatg tatgttgatg
     6301 ttatttctca ccgtcgccat ggtgcatatt gtggcgctta tgagccccgg tcccgatttc
     6361 ttttttgtct ctcagaccgc tgtcagtcgt tcccgtaaag aagcgatgat gggcgtgctg
     6421 ggcattacct gcggtgtaat ggtttgggct gggattgcgt tgcttggcct gcatttgatt
     6481 atcgaaaaaa tggcctggct gcatacgctg attatggttg gcggtggcct gtatctctgc
     6541 tggatgggtt accagatgct acgcggtgca ctgaaaaaag aggcggtttc tgcacctgcg
     6601 ccacaggtcg agctggcgaa aagtgggcgc agtttcctga aaggtttact gaccaatctc
     6661 gctaatccga aagcgattat ctactttggc tcggtgttct cattgtttgt cggtgataac
     6721 gttggcacta ccgcgcgctg gggcattttt gcgctgatca ttgtcgaaac gctggcgtgg
     6781 tttaccgtcg ttgccagcct gtttgccctg ccgcaaatgc gccgtggtta tcaacgtctg
     6841 gcgaagtgga ttgatggttt tgccggggcg ttatttgccg gatttggcat tcatttgatt
     6901 atttcgcggt gatgccagac gcgtcttcag agtaagtcgg ataaggcgtt tacgccgcat
     6961 ccgacattat ttttcacgca tgcctcgccg atgctaacag cgctcccacc agcataaaca
     7021 acgagccgaa aatcttattc agcgccttca tctgctttgg tcctttaatc catagagcaa
     7081 tccgttgagc aagggtggcg taaccgatca tcacaataat atcgaccaca atagtggtga
     7141 cgccgagcac gatatactgc atcagttgcg gctgttgcgg catgatgaat tgcggaaata
     7201 gcgccgccag aaacacaata cttttgggat tggtgagatt cacaaaaact gcgcgctgga
     7261 acaaatgtcg acgcgattga gtagaggcca gcgatttaag gtcaattgca ccagcggcgc
     7321 gccactgctg gattcccagc caaatcaagt aagccgcgcc tgcccacttc aacacttcaa
     7381 acgcaatcac tgagcgggaa aatagcgtcc ccaaccctac gccaaccagc acaatatgaa
     7441 tcgccagtcc ggtctgaagc ccagcaatag acgccaccgc gccgcgataa ccgtggttga
     7501 gcgaggtggt catagtgttg attgcaccag agcctggcga caggcttaaa atgatcgatg
     7561 tcagcaggta ggcaaaccac cattctaagg tcatgatgaa ctcccggtgt gtctattttt
     7621 gtgccacaat acgctactgt cgcagcgttg tgtcaggcac gctaaaaaaa acgattttac
     7681 gtggtttaag aggcagatta cccgatgttt cagcagcaaa aagactggga aacaagagaa
     7741 aacgcgtttg ctgcttttac catgggaccg ctgactgatt tctggcgtca gcgtgatgaa
     7801 gcagagttta ctggtgtgga tgacattccg gtgcgctttg tccgttttcg cgcacagcac
     7861 catgaccggg tggtagtcat ctgcccgggg cgtattgaga gctacgtaaa atatgcggaa
     7921 ctggcctacg atttgttcca tttggggttt gatgtcttaa tcatcgacca tcgcgggcag
     7981 ggacgttccg gtcgcctgtt agccgatccg catctcgggc atgttaatcg ctttaatgat
     8041 tatgttgatg atctggcggc attctggcaa caggaggtcc agcccggtcc gtggcgtaaa
     8101 cgctatatac tggcacattc gatgggcggt gcgatctcca cattatttct gcaacgccat
     8161 ccaggtgtat gtgacgccat tgcgctaact gcgccaatgt ttgggatcgt gattcgtatg
     8221 ccgtcattta tggcacggca gatcctcaac tgggccgaag cgcatccacg tttccgtgat
     8281 ggctatgcaa taggcaccgg gcgctggcgc gcgttgccgt ttgctatcaa cgtactgacc
     8341 cacagcagac agcgatatcg acgtaactta cgcttctatg ctgatgaccc aacgattcgc
     8401 gtcggtgggc cgacctacca ttgggtacgc gaaagtattc tggctggcga acaggtgtta
     8461 gccggtgcgg gtgatgacgc cacgccaacg cttctcttgc aggctgaaga ggaacgcgtg
     8521 gtggataacc gcatgcatga ccgtttttgt gaactccgca ccgccgcggg ccatcctgtc
     8581 gaaggaggac ggccgttggt aattaaaggt gcttaccatg agatcctttt tgaaaaggac
     8641 gcaatgcgct cagtcgcgct ccacgccatc gttgattttt tcaacaggca taactcaccc
     8701 agcggaaacc gctctacaga ggtttaaatt tcttatgtac caggttgttg cgtctgattt
     8761 agatggcacg ttactttctc ccgaccatac gttatcccct tacgccaaag aaactctgaa
     8821 gctgctcacc gcgcgcggca tcaactttgt gtttgcgacc ggtcgtcacc acgttgatgt
     8881 ggggcaaatt cgcgataatc tggagattaa gtcttacatg attacctcca atggtgcgcg
     8941 cgttcacgat ctggatggta atctgatttt tgctcataac ctggatcgcg acattgccag
     9001 cgatctgttt ggcgtagtca acgacaatcc ggacatcatt actaacgttt atcgcgacga
     9061 cgaatggttt atgaatcgcc atcgcccgga agagatgcgc ttttttaaag aagcggtgtt
     9121 caaatatgcg ctgtatgagc ctggattact ggagccggaa ggcgtcagca aagtgttctt
     9181 cacctgcgat tcccatgaac aactgctgcc gctggagcag gcgattaacg ctcgttgggg
     9241 agatcgcgtc aacgtcagtt tctctacctt aacctgtctg gaagtgatgg cgggcggcgt
     9301 ttcaaaaggc catgcgctgg aagcggtggc gaagaaactg ggctacagcc tgaaggattg
     9361 tattgcgttt ggtgacggga tgaacgacgc cgaaatgctg tcgatggcgg ggaaaggctg
     9421 cattatgggc agtgcgcacc agcgtctgaa agaccttcat cccgagctgg aagtgattgg
     9481 tactaatgcc gacgacgcgg tgccgcatta tctgcgtaaa ctctatttat cgtaatcgtt
     9541 ctttatttgg tcagttgtca acctgatact tcgctacaat ggatactcgt taatcaaaga
     9601 gttttccatt gtggcgctac ttatcatcac cacgattctg tgggccttct cctttagctt
     9661 ttatggcgag taccttgcgg ggcacgtcga tagctatttt gcggtgctgg tgcgcgttgg
     9721 cctggcggca ctcgtttttc tgccgtttct gcgtacccgt ggcaatagcc tgaaaacagt
     9781 cggcctgtat atgctggtgg gcgcgatgca gcttggcgtg atgtatatgc tgagtttccg
     9841 cgcttatctc tatctgacgg tttccgaact gctgctgttc accgtactga cgccgctcta
     9901 catcacgctg atttatgaca tcatgagtaa gcgccgtctg cgctggggat atgcttttag
     9961 tgccttgttg gcggtgattg gtgccgggat tattcgctat gatcaggtca ccgaccattt
    10021 ctggactggc ttgttgctgg tgcaactctc caatatcact tttgccatcg gcatggtggg
    10081 ttacaaacgc ctgatggaaa ctcgcccgat gccgcagcat aacgcctttg cgtggttcta
    10141 tcttggcgcg ttcctggtgg cggtaattgc atggttcttg ctgggaaatg cgcagaaaat
    10201 gccgcaaacc acgttgcaat ggggcattct ggtgtttctt ggcgtggtgg cttccgggat
    10261 tggctacttt atgtggaact acggcgcgac gcaggtggac gccggaacgc tgggaattat
    10321 gaataatatg cacgttccgg cagggctgct ggtaaacctg gctatctggc accaacagcc
    10381 gcactggcca acgtttatta caggcgcgct ggtgatcctg gcctcactgt gggtgcatcg
    10441 taagtgggtc gctccgcgct cttcacaaac ggcagatgat cgcaggcgtg attgcgcgct
    10501 gagcgaataa acgcttccgt aactggctga cgctgctcgc catcgcgcac ggcggcgtac
    10561 agtcggctcc acaagccttc gcccagggtt ttggtcacca ccagaccctg gcgctcaaaa
    10621 ctctctacta cccaatgcgg tagcgcggca atacccatcc gcgcggcaac catctgaatc
    10681 aacaataagg tgttatcgac gcttttcagt gacgggctga cgcctgccgg ctgaagaaaa
    10741 tgccgccaga catccagtcg actacgctgc accggataaa tcaacagcgt ctcgctggcg
    10801 agatcttccg gtgtaattcg cgttttcgcc gccagtggat ggtcaggtgc taacaccaga
    10861 cgcacttcat agtcgaacat cggcgaataa tgcaggccac tgcgcggcag gatatcggag
    10921 gtcatcacca gatccagctc gccctgttgc aacgcgggct gcgggtcaaa cgtcacgccc
    10981 gatttaaaat ccatctctac ctgcggccag ttcttatgga aattttctaa cgcgggcgtc
    11041 agccactgaa tacagctatg gcactcaatg gcaatgcgca gacgcgtctg ctgcggttca
    11101 ttgcaggctt gcagtgcctg gctaatttgc ggcagcacct ggtttgccag ttgcaacagg
    11161 atttctccct gcggtgtaaa gcgtagcggc tggctcttac gcacaaatag ccggaagcca
    11221 aggcgttgtt ccagatcgct aaactggtga gacagggcgg attgcgtctg atgcaacgtc
    11281 gccgcagcgg ctgcgagaga gccgcagttc cgcaacgctt gtagcgtttt caggtgtttt
    11341 acttcgatca tgaaagtcct tcacttcggc atgaataatt tgcgcttgag gaatatacag
    11401 taaccgccaa ttatggatgt gtaaacatct ggacggctaa atactaaaaa ttccataagg
    11461 ggcatatcat ataatgacaa ttcttaatca caccctcggt ttccctcgcg ttggcctgcg
    11521 tcgcgagctg aaaaaagcgc aagaaagtta ttgggcgggg aactccacgc gtgaagaact
    11581 gctgacagta gggcgtgaac tgcgtgctcg tcactgggat caacaaaagc aagcgggtat
    11641 cgacctgctg ccggtgggcg attttgcctg gtacgatcat gttctgacca ccagtctgct
    11701 gctgggtaat gttccgccac gtcatcagaa caaagacggt tcggtagata tcgacaccct
    11761 gttccgtatt ggtcgtggac gtgcgccgac tggcgaacct gcggcggcag cggaaatgac
    11821 caaatggttt aacaccaact atcactacat ggtgccggaa ttcgttaaag gccaacagtt
    11881 caaactgacc tggacgcagc tgctggagga agtggacgag gcgctggcgc tgggccacaa
    11941 cgttaagcct gtgctgctgg ggccggttac ttacctgtgg ctggggaaag tgaaaggtga
    12001 acagtttgac cgccttagcc tgctgaacga cattctgccg gtttatcagc aagtgctggc
    12061 agaactggcg aaacgcggca tcgagtgggt acagattgat gaacccgcgc tggtactgga
    12121 actaccacag gcgtggctgg acgcatacaa acccgcttac gacgcgctcc agggacaggt
    12181 gaaactgctg ctgaccacct attttgaagg cgtaacgcca aatctcgaca cgattactgc
    12241 gctgcctgtt cagggtctgc atgttgacct cgtacatggt aaagatgacg ttgctgaact
    12301 gcacaagcgc ctgccttctg actggttgct gtctgcgggt ctgatcaatg gtcgtaacgt
    12361 ctggcgcgcc gatcttaccg agaaatatgc gcaaattaag gacattgtcg gcaaacgtga
    12421 tttgtgggtg gcatcttcct gctcgttgct gcacagcccc atcgacctga gcgtggaaac
    12481 gcgtcttgat gcagaagtga aaagctggtt tgccttcgcc ctacaaaaat gccatgaact
    12541 ggcactgctg cgcgatgcgc tgaacagtgg tgacacggca gctctggcag agtggagcgc
    12601 cccgattcag gcacgtcgtc actctacccg cgtacataat ccggcggtag aaaagcgtct
    12661 ggcggcgatc accgcccagg acagccagcg tgcgaatgtc tatgaagtgc gtgccgaagc
    12721 ccagcgtgcg cgttttaaac tgccagcgtg gccgaccacc acgattggtt ctttcccgca
    12781 aaccacggaa attcgtaccc tgcgtctgga tttcaaaaag ggcaatctcg acgccaataa
    12841 ctaccgcacg ggcattgcgg aacatatcag gcaggccatt gttgaacagg aacgtttggg
    12901 actggatgtg ctggtacatg gcgaggccga gcgtaatgac atggtggaat actttggcga
    12961 gcacctcgac gggtttgtct ttacgcaaaa cggttgggta cagagctacg gttcccgctg
    13021 cgtgaagcca ccgattgtta ttggtgacgt tagtcgcccg gcaccgatta ccgtggagtg
    13081 ggcgaagtat gcgcaatcgc tgaccgacaa accggtgaaa gggatgctga cggggccggt
    13141 gaccatactc tgctggtcgt tcccgcgtga agatgtcagc cgtgaaacca tcgccaaaca
    13201 gattgcgctg gcgctgcgtg atgaggtggc cgatctggaa gcggcaggga ttggtatcat
    13261 ccagattgac gaaccggcgc tgcgcgaagg tttaccactg cgtcgtagcg actgggacgc
    13321 ctatctccag tggggcgtag aggccttccg tatcaacgcc gccgtggcga aagatgacac
    13381 acaaatccac actcacatgt gttattgcga gttcaacgac atcatggatt ccattgcggc
    13441 gctggatgca gacgtcatca ccatcgaaac ctcgcgttcc gacatggagt tgctggagtc
    13501 gtttgaagag tttgattatc cgaatgaaat cggtccaggc gtctatgaca ttcactcgcc
    13561 aaacgtaccg agcgtggaat ggattgaagc cctgctgaag aaagcggcaa aacgcattcc
    13621 ggcagagcgc ctgtgggtca acccagactg tggcctgaaa acgcgcggct ggccagaaac
    13681 ccgcgcggca ctggcgaaca tggtgcaggc ggcgcagaat ttgcgtctgg ggtaaatcca
    13741 aaccgggtgg taataccacc cggtcttttc tcattacagc gacttcttcc caccatactg
    13801 cttaaaccat tccagcatac gctgccagcc atctttcgca gattcggcat gatagctcgg
    13861 gcgataatca gcgttgaatg catgcccggc atccgggtag acgataatct ctgctttcgc
    13921 attagcagcc cgcagcgcct ggcgcatcgt ttcaacgctc tcctgcggaa tgctgttatc
    13981 ctgaccgcca tataagccga gaaccggcgc gttaagatcg gttgcgatat caacaggttg
    14041 tttcggtgaa ttcagcgact tatcgcccgt cagtttgccg taccacgcca ctgcggcttt
    14101 tagctgtgga ttatgcgcgg catacagcca ggtgatacgt ccaccccagc agaatccggt
    14161 gatcattaaa cgatgaacat cgccgccgtt gcgggaagcc caactggcga catgatcgag
    14221 atcggccagc acctgcgagt caggcacttt tgctaccaga ccgctaagca acgtggggat
    14281 atcggcaaaa tcattcggat cgccttcgcg gaagtaaagt tcaggtgcga tagccagata
    14341 cccctccagc gccagacggc gacaaatgtc gcggatatgt tcatgcacgc caaaaatttc
    14401 ctgcactaca atgaccactg gcagtgggcc atcgctttgc tttggtctgg catggtaagc
    14461 aggcatgtta tccccttgtg aagggataga ggtgaagccc gccacaatcg cgtcgtccgg
    14521 ggtctgaacg atggtcgaag cgagaggcga tgcagcaggt gcaaatccag attgttgtgt
    14581 tgttgccatg gtattctccg tacccttata aaaatgttgc gcaatgttaa ctatagtcag
    14641 catgcaacaa atcacattgc ctgaatcggc tcatctttta tgcagtcctg cagaatgaag
    14701 agtgatttat gtgatttgaa tcacttttgg tgggtaaatt tatgcaacgc atttgcgtca
    14761 tggtgatgag tatcacgaaa aaatgttaaa cccttcggta aagtgtcttt ttgcttcttc
    14821 tgactaaacc gattcacaga ggagttgtat atgtccaagt ctgatgtttt tcatctcggc
    14881 ctcactaaaa acgatttaca aggggctacg cttgccatcg tccctggcga cccggatcgt
    14941 gtggaaaaga tcgccgcgct gatggataag ccggttaagc tggcatctca ccgcgaattc
    15001 actacctggc gtgcagagct ggatggtaaa cctgttatcg tctgctctac cggtatcggc
    15061 ggcccgtcta cctctattgc tgttgaagag ctggcacagc tgggcattcg caccttcctg
    15121 cgtatcggta caacgggcgc tattcagccg catattaatg tgggtgatgt cctggttacc
    15181 acggcgtctg tccgtctgga tggcgcgagc ctgcacttcg caccgctgga attcccggct
    15241 gtcgctgatt tcgaatgtac gactgcgctg gttgaagctg cgaaatccat tggcgcgaca
    15301 actcacgttg gcgtgacagc ttcttctgat accttctacc caggccagga acgttacgat
    15361 acttactctg gtcgcgtagt tcgtcacttt aaaggttcta tggaagagtg gcaggcgatg
    15421 ggcgtaatga actatgaaat ggaatctgca accctgctga ccatgtgtgc aagtcagggc
    15481 ctgcgtgccg gtatggtagc gggtgttatc gttaaccgca cccagcaaga gatcccgaat
    15541 gctgagacga tgaaacaaac tgaaagccaa gcggtgaaaa tcgtggtgga agcggcgcgt
    15601 cgtctgctgt aattctcttc tcctgtctga aggccgacgc gttcggcctt ttgtattttt
    15661 gcgtagcgcc tcgcaggaaa tgcctttcca actggacgtt tgtacagcac aattctattt
    15721 tgtgcgggta agttgttgcg tcaggaggcg ttgtggattt ctcaatcatg gtttacgcag
    15781 ttattgcgtt ggtgggtgtg gcaattggct ggctgtttgc cagttatcaa catgcgcagc
    15841 aaaaagccga gcaattagct gaacgtgaag agatggtcgc ggagttaagc gcggcaaaac
    15901 aacaaattac ccaaagcgag cactggcgtg cagagtgcga gttactcaat aacgaagtgc
    15961 gcagcctgca aagtattaac acctctctgg aggccgatct gcgtgaagta accacgcgga
    16021 tggaagccgc acagcaacat gctgacgata aaattcgcca gatgattaac agcgagcagc
    16081 gcctcagtga gcagtttgaa aacctcgcca accgtatttt tgagcacagc aatcgccggg
    16141 ttgatgagca aaaccgtcag agtctgaaca gcctgttgtc gccgctacgt gaacaactgg
    16201 acggtttccg ccgtcaggtt caggacagct tcggtaaaga agcacaagaa cgccataccc
    16261 tgacccacga aattcgcaat ctccagcaac tcaacgcgca aatggcccag gaagcgatca
    16321 acctgacgcg cgcgctgaaa ggcgacaata aaacccaggg caactggggc gaggtagtat
    16381 tgacgcgggt gctggaggct tccggtctgc gtgaagggta tgaatatgaa acccaggtca
    16441 gcatcgaaaa tgacgcccgc tcgcggatgc agccggatgt catcgtgcgg ctgccgcagg
    16501 gaaaagatgt ggtgatcgac gccaaaatga cgctggtcgc ctatgaacgc tattttaacg
    16561 ccgaagacga ctacacccgc gaaagcgcgc tacaggaaca tatcgcgtcg gtgcgtaacc
    16621 atatccgttt gctgggacgc aaagattatc aacagctgcc ggggctgcga actctggatt
    16681 acgtgctgat gtttattccc gttgaacccg cttttttact ggcgcttgac cgccagccgg
    16741 agctgatcac cgaagcgttg aaaaacaata tcatgctggt tagcccgact acgctgctgg
    16801 tggcgttgcg tactattgcc aacctgtggc gttatgagca tcaaagccgc aacgcccagc
    16861 aaatcgccga tcgtgccagc aagctgtacg acaagatgcg tttgttcatc gatgacatgt
    16921 ccgcgattgg tcaaagtctc gacaaagcgc aggataacta ccgccaggca atgaaaaaac
    16981 tctcttcagg tcgcggaaat gtgctggcgc aggcagaagc gtttcgcggt ttaggagtag
    17041 aaattaaacg cgagattaat ccggatttgg ctgaacaggc ggtgagccag gatgaagagt
    17101 atcgacttcg gtcggttccg gagcagccga atgatgaagc ttatcaacgc gatgatgaat
    17161 ataatcagca gtcgcgctag cccattaggg gtagttaagc cgggtagaaa tctagggcat
    17221 cgacgcccaa tctgttacac ttctggaaca attttttgat gagcaggcat tgagatggtg
    17281 gataagtcac aagaaacgac gcactttggt tttcagaccg tcgcgaagga acaaaaagcg
    17341 gatatggtcg cccacgtttt ccattccgtg gcatcaaaat acgatgtcat gaatgatttg
    17401 atgtcatttg gtattcatcg tttgtggaag cgattcacga ttgattgcag cggcgtacgc
    17461 cgtgggcaga ccgtgctgga tctggctggt ggcaccggcg acctgacagc gaaattctcc
    17521 cgcctggtcg gagaaactgg caaagtggtc cttgctgata tcaatgaatc catgctcaaa
    17581 atgggacgcg agaagctgcg taatatcggt gtgattggca acgttgagta tgttcaggcg
    17641 aacgctgagg cgctgccgtt cccggataac acctttgatt gcatcaccat ttcgtttggt
    17701 ctgcgtaacg tcaccgacaa agataaagca ctgcgttcaa tgtatcgcgt gctgaaaccc
    17761 ggcggccgcc tgctggtgct tgagttctcg aagccaatta tcgagccgct gagcaaagcc
    17821 tatgatgcat actccttcca tgtgctgccg cgtattggct cactggtcgc gaacgacgcc
    17881 gacagctacc gttatctggc agaatccatc cgtatgcatc ccgatcagga taccctgaaa
    17941 gccatgatgc aggatgccgg attcgaaagt gtcgactact acaatctgac ggcgggggtt
    18001 gtggcgctgc atcgtggtta taagttctga caggagaccg gaaatgcctt ttaaaccttt
    18061 agtgacggca ggaattgaaa gtctgctcaa caccttcctg tatcgctcac ccgcgctgaa
    18121 aacagcccgc tcgcgtctgc tgggtaaagt attgcgcgtg gaggtaaaag gcttttcgac
    18181 gtcattgatt ctggtgttca gcgaacgcca ggttgatgta ctgggcgaat gggcaggcga
    18241 tgctgactgc accgttatcg cctacgccag tgtgttgccg aaacttcgcg atcgccagca
    18301 gcttaccgca ctgattcgca gtggtgagct ggaagtgcag ggcgatattc aggtggtgca
    18361 aaacttcgtt gcgctggcag atctggcaga gttcgaccct gcggaactgc tggcccctta
    18421 taccggtgat atcgccgctg aaggaatcag caaagccatg cgcggaggcg caaagttcct
    18481 gcatcacggc attaagcgcc agcaacgtta tgtggcggaa gccattactg aagagtggcg
    18541 tatggcaccc ggtccgcttg aagtggcctg gtttgcggaa gagacggctg ccgtcgagcg
    18601 tgctgttgat gccctgacca aacggctgga aaaactggag gctaaatgac gccaggtgaa
    18661 gtacggcgcc tatatttcat cattcgcact tttttaagct acggacttga tgaactgatc
    18721 cccaaaatgc gtatcaccct gccgctacgg ctatggcgat actcattatt ctggatgcca
    18781 aatcggcata aagacaaact tttaggtgag cgactacgac tggccctgca agaactgggg
    18841 ccggtttgga tcaagttcgg gcaaatgtta tcaacccgcc gcgatctttt tccaccgcat
    18901 attgccgatc agctggcgtt attgcaggac aaagttgctc cgtttgatgg caagctggcg
    18961 aagcagcaga ttgaagctgc aatgggcggc ttgccggtag aagcgtggtt tgacgatttt
    19021 gaaatcaagc cgctggcttc tgcttctatc gcccaggttc ataccgcgcg attgaaatcg
    19081 aatggtaaag aggtggtgat taaagtcatc cgcccggata ttttgccggt tattaaagcg
    19141 gatctgaaac ttatctaccg tctggctcgc tgggtgccgc gtttgctgcc ggatggtcgc
    19201 cgtctgcgcc caaccgaagt ggtgcgcgag tacgaaaaga cattgattga tgaactgaat
    19261 ttgctgcggg aatctgccaa cgccattcag cttcggcgca attttgaaga cagcccgatg
    19321 ctctacatcc cggaagttta ccctgactat tgtagtgaag ggatgatggt gatggagcgc
    19381 atttacggca ttccggtgtc tgatgttgcg gcgctggaga aaaacggcac caacatgaaa
    19441 ttgctggcgg aacgcggcgt gcaggtgttc ttcactcagg tctttcgcga cagctttttc
    19501 catgccgata tgcaccctgg caacatcttc gtaagctatg aacacccgga aaacccgaaa
    19561 tatatcggca ttgattgcgg gattgttggc tcgctaaaca aagaagataa acgctatctg
    19621 gcagaaaact ttatcgcctt ctttaatcgc gactatcgca aagtggcaga gctacacgtc
    19681 gattctggct gggtgccacc agataccaac gttgaagagt tcgaatttgc cattcgtacg
    19741 gtctgtgaac ctatctttga gaaaccgctg gccgaaattt cgtttggaca tgtactgtta
    19801 aatctgttta atacggcgcg tcgcttcaat atggaagtgc agccgcaact ggtgttactc
    19861 cagaaaaccc tgctctacgt cgaaggggta ggacgccagc tttatccgca actcgattta
    19921 tggaaaacgg cgaagccttt cctggagtcg tggattaaag atcaggtcgg tattcctgcg
    19981 ctggtgagag catttaaaga aaaagcgccg ttctgggtcg aaaaaatgcc agaactgcct
    20041 gaactggttt acgacagttt gcgccagggc aagtatttac agcacagtgt tgataagatt
    20101 gcccgcgagc ttcagtcaaa tcatgtacgt cagggacaat cgcgttattt tctcggaatt
    20161 ggcgctacgt tagtattaag tggcacattc ttgttggtca gccgacctga gtgggggctg
    20221 atgcccggct ggttaatggc aggtggtctg atcgcctggt ttgtcggttg gcgcaaaaca
    20281 cgctgatttt ttcatcgctc aaggcgggcc gtgtaacgta taatgcggct ttgtttaatc
    20341 atcatctacc acagaggaac atgtatgggt ggtatcagta tttggcagtt attgattatt
    20401 gccgtcatcg ttgtactgct ttttggcacc aaaaagctcg gctccatcgg ttccgatctt
    20461 ggtgcgtcga tcaaaggctt taaaaaagca atgagcgatg atgaaccaaa gcaggataaa
    20521 accagtcagg atgctgattt tactgcgaaa actatcgccg ataagcaggc ggatacgaat
    20581 caggaacagg ctaaaacaga agacgcgaag cgccacgata aagagcaggt gtaatccgtg
    20641 tttgatatcg gttttagcga actgctattg gtgttcatca tcggcctcgt cgttctgggg
    20701 ccgcaacgac tgcctgtggc ggtaaaaacg gtagcgggct ggattcgcgc gttgcgttca
    20761 ctggcgacaa cggtgcagaa cgaactgacc caggagttaa aactccagga gtttcaggac
    20821 agtctgaaaa aggttgaaaa ggcgagcctc actaacctga cgcccgaact gaaagcgtcg
    20881 atggatgaac tacgccaggc cgcggagtcg atgaagcgtt cctacgttgc aaacgatcct
    20941 gaaaaggcga gcgatgaagc gcacaccatc cataacccgg tggtgaaaga taatgaagct
    21001 gcgcatgagg gcgtaacgcc tgccgctgca caaacgcagg ccagttcgcc ggaacagaag
    21061 ccagaaacca cgccagagcc ggtggtaaaa cctgctgcgg acgctgaacc gaaaaccgct
    21121 gcaccttccc cttcgtcgag tgataaaccg taaacatgtc tgtagaagat actcaaccgc
    21181 ttatcacgca tctaattgag ctgcgtaagc gtctgctgaa ctgcattatc gcggtgatcg
    21241 tgatattcct gtgtctggtc tatttcgcca atgacatcta tcacctggta tccgcgccat
    21301 tgatcaagca gttgccgcaa ggttcaacga tgatcgccac cgacgtggcc tcgccgttct
    21361 ttacgccgat caagctgacc tttatggtgt cgctgattct gtcagcgccg gtgattctct
    21421 atcaggtgtg ggcatttatc gccccagcgc tgtataagca tgaacgtcgc ctggtggtgc
    21481 cgctgctggt ttccagctct ctgctgtttt atatcggcat ggcgttcgcc tactttgtgg
    21541 tctttccgct ggcatttggc ttccttgcca ataccgcgcc ggaaggggta caggtatcca
    21601 ccgacatcgc cagctattta agcttcgtta tggcgttgtt tatggcgttt ggtgtctcct
    21661 ttgaagtgcc tgtggcaatt gtgctgctgt gctggatggg gattacctcg ccagaagact
    21721 tacgcaaaaa acgcccgtat gtgctggttg gtgcattcgt tgtcgggatg ctgctgacac
    21781 cgccggatgt cttctcgcaa acgctgttgg cgatcccgat gtactgtctg tttgaaatcg
    21841 gtgtcttctt ctcacgcttt tacgttggta aagggcgaaa tcgggaagag gaaaacgacg
    21901 ctgaagcaga aagcgaaaaa actgaagaat aaattcaacc gcccgtcagg gcggttgtca
    21961 tatggagtac aggatgtttg atatcggcgt taatttgacc agttcgcaat ttgcgaaaga
    22021 ccgtgatgat gttgtagcgc gcgcttttga cgcgggagtt aatgggctac tcatcaccgg
    22081 cactaacctg cgtgaaagcc agcaggcgca aaagctggcg cgtcagtatt cgtcctgttg
    22141 gtcaacggcg ggcgtacatc ctcacgacag cagccagtgg caagctgcga ctgaagaagc
    22201 gattattgag ctggccgcgc agccagaagt ggtggcgatt ggtgaatgtg gtctcgactt
    22261 taaccgcaac ttttcgacgc cggaagagca ggaacgcgct tttgttgccc agctacgcat
    22321 tgccgcagat ttaaacatgc cggtatttat gcactgtcgc gatgcccacg agcggtttat
    22381 gacattgctg gagccgtggc tggataaact gcctggtgcg gttcttcatt gctttaccgg
    22441 cacacgcgaa gagatgcagg cgtgcgtggc gcgtggaatt tatatcggca ttaccggttg
    22501 ggtttgcgat gaacgacgcg ggctggagct gcgggaattg ttgccgttga ttccggcgga
    22561 gaaattgctg atcgaaactg atgcgccgta tctgctcccg cgcgatctca cgccaaagcc
    22621 atcatcccgg cgcaacgagc cagcccatct gccccatatt ttgcaacgta ttgcgcactg
    22681 gcgtggagaa gatgccgcat ggctggctgc caccacggat gccaatgtca aaacactgtt
    22741 tgggattgcg ttttagagtt tgcggaactc ggtgttcttc acactgtgct taatctcttt
    22801 attaataaga ttaagcaata gcatggagcg agcctcacca tcgggttcgg tgaaaatggc
    22861 ctgaaagcct tcgaacgcgc cttcggtaat aatcacctta tcacccggat aaggggttgc
    22921 cggatcgaca atgtctttcg gtttatatac cgatagctga tgaatcaccg ccgatgggac
    22981 tatcgctggc gacgcgccaa agcgcacgaa gtggctgaca ccgcgggtcg cgttgatagt
    23041 cgtggtatga atcacttctg gatcaaattc gacaaacagg tagttgggaa acaatggctc
    23101 actgactgca gtacgttttc cacgcacgat tttttccagg gtgatcatcg gtgccaggca
    23161 attcacagcc tgtctttcga ggtgttcctg ggcacgttga agttgcccgc gcttgcagta
    23221 cagtaaatac caggattgca taatgactct tatccgttta atcggggcgc aaggatagca
    23281 aaagctttac gctaagttaa ttatattccc cggtttgcgt tataccgtca gagttcacgc
    23341 taatttaaca aatttacagc atcgcaaaga tgaacgccgt ataatgggcg tagattaaga
    23401 ggctacaatg gacgccatga aatataacga tttacgcgac ttcctgacac tgcttgaaca
    23461 gcagggtgag ctaaaacgta tcacgctccc ggtggatccg catctggaaa tcactgaaat
    23521 tgctgaccgc actttgcgtg ccggtgggcc tgcgctgttg ttcgaaaacc ctaaaggcta
    23581 ctcaatgccg gtgctgtgca acctgttcgg tacgccaaag cgcgtggcaa tgggcatggg
    23641 gcaggaagat gtttcggcgc tacgtgaagt tggtaaatta ttggcgtttc tgaaagagcc
    23701 ggagccgcca aaaggtttcc gcgacctgtt tgataaactg ccgcagttta agcaagtatt
    23761 gaacatgccg acaaagcggc tgcgtggtgc gccctgccaa caaaaaatcg tctctggcga
    23821 tgacgtcgat ctcaatcgca ttcccattat gacctgctgg ccggaagatg ccgcgccgct
    23881 gattacctgg gggctgacag tgacgcgcgg cccgcataaa gagcggcaga atctgggcat
    23941 ttatcgccag cagctgattg gtaaaaacaa actgattatg cgctggctgt cgcatcgcgg
    24001 cggcgcgctg gattatcagg agtggtgtgc ggcgcatccg ggcgaacgtt tcccggtttc
    24061 tgtggcgctg ggtgccgatc ccgccacgat tctcggtgca gtcacccccg ttccggatac
    24121 actttcagag tatgcgtttg ccggattgct gcgcggtacc aagaccgaag tggtgaagtg
    24181 tatctccaat gaccttgaag tgcccgccag tgcggagatt gtgctggaag ggtatatcga
    24241 acaaggtgaa acggcgccgg aagggccgta tggcgaccac accggttact ataacgaagt
    24301 cgatagtttc cctgtcttta ctgtgacgca tattacccag cgtgaagatg cgatttacca
    24361 ttccacctat accgggcgtc cgcctgatga acctgcggta ctgggcgtgg cgttgaacga
    24421 agtgtttgtg ccgattctgc aaaaacagtt cccggaaatt gtcgattttt acctgccacc
    24481 ggaaggctgt tcttatcgtc tggcggtagt gacgatcaaa aaacagtacg ccggacacgc
    24541 gaagcgcgtc atgatgggcg tctggtcgtt cttacgccag tttatgtaca ctaaatttgt
    24601 gatcgtttgc gatgatgacg tcaacgcacg cgactggaac gatgtgattt gggcgattac
    24661 cacccgtatg gacccggcgc gggatactgt tctggtagaa aatacgccta ttgattatct
    24721 ggattttgcc tcgcctgtct ccgggctggg ttcaaaaatg gggctggatg ccacgaataa
    24781 atggccgggg gaaacccagc gtgaatgggg acgtcccatc aaaaaagatc cagatgttgt
    24841 cgcgcatatt gacgccatct gggatgaact ggctattttt aacaacggta aaagcgcctg
    24901 atgcgcgttt gttttgccct atttatcgat ccgacagaga aagcgcatga caaccttaag
    24961 ctgtaaagtg acctcggtag aagctatcac ggataccgta tatcgtgtcc gcatcgtgcc
    25021 agatgcggcc ttttcttttc gcgctggtca gtatttgatg gtagtgatgg atgagcgcga
    25081 caaacgtccg ttctcaatgg cttcgacgcc ggatgaaaaa gggtttatcg agctgcatat
    25141 tggcgcttct gaaatcaacc tttacgcgaa agcagtcatg gaccgcatcc tcaaagatca
    25201 tcaaatcgtg gtcgatattc cccacggaga agcgtggctg cgcgatgatg aagagcgtcc
    25261 gatgattttg attgcgggcg gcaccgggtt ctcttatgcc cgctcgattt tgctgacagc
    25321 gttggcgcgt aacccaaacc gtgatatcac catttactgg ggcgggcgtg aagagcagca
    25381 tctgtatgat ctctgcgagc ttgaggcgct ttcgttgaag catcctggtc tgcaagtggt
    25441 gccggtggtt gaacaaccgg aagcgggctg gcgtgggcgt actggcaccg tgttaacggc
    25501 ggtattgcag gatcacggta cgctggcaga gcatgatatc tatattgccg gacgttttga
    25561 gatggcgaaa attgcccgcg atctgttttg cagtgagcgt aatgcgcggg aagatcgcct
    25621 gtttggcgat gcgtttgcat ttatctgaga tataaaaaaa cccgcccctg acaggcggga
    25681 agaacggcaa ctaaaacttt attcagtggc atttagatct atgtcgcatc cggcattcgg
    25741 cacacga
//
LOCUS       DAZUDJ010000068        25519 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.068, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000068 DAZUDJ010000000
VERSION     DAZUDJ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25519
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.068"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            7..396
                     /locus_tag="ACHY1N_003789"
     CDS             7..396
                     /locus_tag="ACHY1N_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046009.1"
                     /translation="MKRYIKWFAITIFISMLSACARTAPVQQISTTVSVGHTQEQVKN
                     AILKAGAQRKWIMTQVSPGVIKARYQTRNHVAEVRITYTATYYNIKYDSSLNLQASDG
                     KIHKNYNRWVRNLDKDIQVNLSTGATL"
     gene            461..1519
                     /locus_tag="ACHY1N_003790"
     CDS             461..1519
                     /locus_tag="ACHY1N_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HFS4046010.1"
                     /translation="MYEQDTLSALDAITEAQRIAFAPMLFQAALCLRNAGILDYLDQQ
                     GKQGAPLNAITEHTVLNEYAVGVLLDMGLSGRIITCKEGIYYLAKIGHYLLHDTMTRV
                     NMDFTQDVCYQGLFFLADSLNEGKPSGLKVFGDWPTIYPALSQLPDVARDSWFAFDHY
                     YSDGAFNAALPYVFANNPTTLYDVGGNTGKWALRCCKFNENIAVTLLDLPQQIVLAKK
                     NIANAGFSDRIDFHAVDMLSDAPLPGEADIWWMSQFLDCFSPEQIISILSKIASVMKP
                     GAKLCIMELFWDAQRFEATSFSLNASSLYFTCMANGNSRFYSAEKFYDYLNKAGFQVA
                     ERHDNLGVGHTLLICQKK"
     gene            1560..2282
                     /locus_tag="ACHY1N_003791"
     CDS             1560..2282
                     /locus_tag="ACHY1N_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312353.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl synthase chain length factor"
                     /protein_id="HFS4046011.1"
                     /translation="MKFALNITNWQALAPGLSDVQQWQAWSRQPWAIDPAAPLAKLSE
                     LPMMTARRLSSGSKLAVECGLTMLRRHQPDAVLYTSRHGELERNYRIVHALATEQALS
                     PTDFALSVHNSSVGNLTIVAKQPIVSSSLSAGRDSFQQGLCEVLSLLQAGYQRVLMVD
                     FDGFLPEFYHPQLPAEMPTWPYAVALVIEAGDDWQCETQPAIAVNETTLPQSILFLQH
                     YLQNADAFSLPGERVQWRWSRR"
     gene            2279..3100
                     /locus_tag="ACHY1N_003792"
     CDS             2279..3100
                     /locus_tag="ACHY1N_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312354.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFS4046012.1"
                     /translation="MNKLMSRLGWAWRLVMTGLCFVLFGLGGLLLSVVWFNILLVLVW
                     DTSRRRRLARRSIAASFRLFLTVAKGLGVLDYRIDGAEILRQERGCLVVANHPTLIDY
                     VLLASVMPETDCLVKSALLKNPFLGGVVRAADYLINSEAETLLPRCQQRLAQGDTILI
                     FPEGTRTKPGEKMTLQRGAANIAVRCTSDLRIVTIGCSEHLLDKQSKWYDVPPARPFF
                     TVEVRGRVEINKFYDATSQEPTLAARQLNRHLLLQLQQGCLPLSGINNASALSGN"
     gene            3075..3332
                     /locus_tag="ACHY1N_003793"
     CDS             3075..3332
                     /locus_tag="ACHY1N_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantetheine-binding protein"
                     /protein_id="HFS4046013.1"
                     /translation="MQALYLEIKNLIISTLNLDDLTPDDIDINAPLFGDGLGLDSIDA
                     LELGLAVKNEYGIVLSAESEEMRQHFFSVATLASFIAAQRA"
     gene            3344..3595
                     /locus_tag="ACHY1N_003794"
     CDS             3344..3595
                     /locus_tag="ACHY1N_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFS4046014.1"
                     /translation="MTDQQTIYQEVSALLVKLFEIDPQDIKPEARLYEDLELDSIDAV
                     DMIVHLQKKTGKKIKPEEFKAVRTVQDVVEAVERLLQEG"
     gene            3600..4181
                     /locus_tag="ACHY1N_003795"
     CDS             3600..4181
                     /locus_tag="ACHY1N_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046015.1"
                     /translation="MSGIRSLPMIKLLTGLLLLVWPFLIWLGLVHNSLHWLLPLMALL
                     LLLRLRQPRRQTGPLQVVTKIVAVVGIVLCVSSFLLKTYQLLLFYPVVVNAVMLAVFG
                     GSLRSTMPIVERLARLQEPDLPEKAVRYTRRVTQVWCLFFIFNGSIALFTTLYGNMPL
                     WTAWNGIIAYLLIGFLTAGEWLIRRKMIKRKTP"
     gene            4178..5536
                     /locus_tag="ACHY1N_003796"
     CDS             4178..5536
                     /locus_tag="ACHY1N_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HFS4046016.1"
                     /translation="MNQTLSLSQWLTASRPVTTPVAWLGEYTWTLGHLRHDVALLIDH
                     LRDQPGNRWALCFENSYLFIVALLATLHSGKIPVIPGHNRAALLNVQRSLFDCVLSDK
                     RLGWNGPQFVVSTSHQMTTSTIAFDDIASDAFIELFTSGSTGQPKQIAKPVISLDQEA
                     NMLATHFADRLLGCRFVASVMPQHLYGLTFRIFLPMALGLPLHAAMLWYSEQLAALSH
                     TYRYAFVSSPAFLKRLDLHLTPPPVEMILSAGGMLPWQDVEKTSTWLNIWPDEIYGST
                     ETGILAWRYRQQDNIPWFTFSDVHLSQESEGVRVFSPLIPAEGLVLDDMLQFNENGQF
                     HLIGRRGRVVKIEEKRISLVEIEQRLLALDGIMDVAAIPLIRNGRQAIGVVVVPNKEA
                     RQIWQCSGGKTLELSWRKALLPWLEPVAVPRYWRIIDEIPVNSMNKRVYAQLQELFHD
                     TP"
     gene            5523..5876
                     /locus_tag="ACHY1N_003797"
     CDS             5523..5876
                     /locus_tag="ACHY1N_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009008217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymyristoyl-ACP dehydratase"
                     /protein_id="HFS4046017.1"
                     /translation="MIRHEIERHLVQPQEMEIVLYLDPMLYWFNGHFAVQPLLPGVAQ
                     LDWVMHYATTLLAPGWRFRSIQNVKFLAPLIPETTVTLQLTWQETSQVLTFCYQRHDG
                     DARHTASSGKIRLCR"
     gene            5867..7543
                     /locus_tag="ACHY1N_003798"
     CDS             5867..7543
                     /locus_tag="ACHY1N_003798"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4046018.1"
                     /translation="MSVNFSPCVLIPCYNHGAMMPGVLARLKPFNLPCIVVDDGSDAA
                     TQQQLDNLVSEQPGVTLIRLAENAGKGAAVMRGLQAAADAGFSHAVQVDADGQHAIED
                     IPKLLALAEQHPVALISGQPIYDDSIPRSRLYGRWVTHVWVWIETLSLQLKDSMCGFR
                     VYPVAPTLQLAKRATIGKRMDFDTEVMVRLYWQGNTSYFVPTRVTYPLDGLSHFDALK
                     DNVRISLMHTRLFFGMLPRIPSLLMCHSSSHWARQSEVKGLWGMRLMLLVWRLLGRTA
                     FTALLYPVVGVYWLTAARARKASQDWLARVRQQQPQAAKINSYQHFLRFGNAMLDKIA
                     SWRGELQLGRDVLFAPGAEAALDVRDPRGKLLLASHLGDVEVCRALAKIEGYKTINAL
                     VFSENAQRFKQIMQEMAPQAGINLMPVTDIGPETAILLKEKLDNGEWVAIVGDRIAVT
                     PQRGGDWRVCWSPFMGQPAPFPQGPFILASILRCPVNLIFALRQHGKLHIHCETFADP
                     LLLPRGERQQALQNAIDHYAARLEHYALQSPLDWFNFFDFWQLPEIQDKE"
     gene            7547..7969
                     /locus_tag="ACHY1N_003799"
     CDS             7547..7969
                     /locus_tag="ACHY1N_003799"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFS4046019.1"
                     /translation="MLNDPRFTAEVELTIPFHDVDMMGVAWHGNYFRYFEVAREALLN
                     QFNYGYRQMKESGYLWPVVDARVKYRHALTFEQRIRVRAHIEEFENRLRIGYQIFDAE
                     TGKRATTGYTIQVAVDEQSRELCFVSPDILFERMGVKP"
     gene            7966..8571
                     /locus_tag="ACHY1N_003800"
     CDS             7966..8571
                     /locus_tag="ACHY1N_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein carrier protein LolA"
                     /protein_id="HFS4046020.1"
                     /translation="MKFLPLLALLISPFVSALTRDDLQQRFTEQPVIRAHFDQTRTIK
                     DLPQPLRSQGQMLIARDQGLLWDQTSPFPMQLLLDDKRMVQVINGQPPQIITAENNPQ
                     MFQFNHLLRALFQADRKVLEQNFRVEFADKGEGRWTLRLTPTTTPLDKIFNTIDLAGQ
                     TYLESIQLNDKQGDRTDIALTQHQLTPAQLTDDERQRFATQ"
     gene            8540..10858
                     /locus_tag="ACHY1N_003801"
     CDS             8540..10858
                     /locus_tag="ACHY1N_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MMPL family transporter"
                     /protein_id="HFS4046021.1"
                     /translation="MTNANALPPSKRPALLWGLVCLVMAAALLILLPQSRLNSSVLAM
                     LPKQAMGDIPPALNDGFMQRLDRQLVWLVSPGKEANPRVAQEWLTLLQKSAALGDIKG
                     PMDAASQQAWGAFFWQHRNGLIDPDTRARLQNGGEAQAKWILSQLYSAFSGVSGKELQ
                     NDPLMLMRGSQLAMAKNGQRLRLMDGWLVTQDPQGHYWYLLHGELAGSSFDMQQTHQL
                     ITTLNTLEKALKTRYPQAQLLSRGTVFYSDYASQQAKQDISTLGVATLLGVILLIVAV
                     FRSLRPLLLCVISIGIGALAGTAATLLIFGELHLMTLVMSMSVIGISADYTLYYLTER
                     MVHGNDVSPWQSLAKVRNALLLALLTTVAAYLIMMLAPFPGIRQMAIFAAVGLSASCL
                     TVLFWHPWLCRGLPVRPVPAMALMLRWLAAWRRNKKLSRGLPVALALFSLAGMSMLRV
                     DDDISQLQALPQHILAQEKAITALTGQSVDQKWFVVYGDSPQQTLRRLEKYTASLEYA
                     KKEGLISNYRTIPLNSLARQEEDLDLLKTAAPTVTKALQNAGLTAVKPDLNAMPVKVD
                     EWLASPASEGWRLLWLTLENGESGVLVPVEGVKSSALLQEIASYYPCGIAWVDRKSSF
                     DELFALYRYVLTGLLLVALAVIACGAVARLGWRKGLISLVPSVLSLGCGLAVLAMSGQ
                     AVNLFSLLALVLVLGIGINYTLFFSNPRGTPLTSLLAIALAMLTTLLTLGMLVFSATQ
                     AISSFGIVLVSGIFTAFLLSPLAMPDKKRTKK"
     gene            10855..11439
                     /locus_tag="ACHY1N_003802"
     CDS             10855..11439
                     /locus_tag="ACHY1N_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3261 domain-containing protein"
                     /protein_id="HFS4046022.1"
                     /translation="MIKSTFWRAFALTATLILTGCSHSQPEQEGRPQAWLQPGTRITL
                     PAPGISPAVNSQQLLTGSFNGKTQSLLVMLNADDQKITLAGLSSVGIRLFLVTYDAQG
                     LRAEQSIVVPQLPPASQVLADVMLSHWPISAWEAQLPAGWTLRDNGDKRELRNTSGKL
                     VTEITYLNRQGKRVPIRIEQHVFKYHITIQYLGD"
     gene            11441..12610
                     /locus_tag="ACHY1N_003803"
     CDS             11441..12610
                     /locus_tag="ACHY1N_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="HFS4046023.1"
                     /translation="MIYISAVGMINALGNNLDEIAANLARGVAPGMRPRAGWLQGHPQ
                     AVLAGVDGELPLIPEKFAAHRSRNNQILLAALAQLQPQVDDAIAKYGCERIAIVLGTS
                     TSGLHEGDTHVNLHTHGQPNTTWHYAQQELGDPSRFLSHWLALDGPAYTLSTACSSSA
                     RAMISGRRLIEAGLVDAAIVGGADTLSRMPINGFHSLESLSPTLCQPFSRDRAGITIG
                     EGAGLMLLTREPQPIALLGVGESSDAYHISAPHPQGEGAIRAINQALTDAQLTPDDVG
                     YINLHGTATQLNDQIESMVVNALFGERVPCSSTKHLTGHTLGAAGITEAAISMLILQR
                     DLPLPAQDFSLSPRDPTLPPCGIIEKPQPLARPVILSNSFAFGGNNASILLGRVS"
     gene            12607..13071
                     /locus_tag="ACHY1N_003804"
     CDS             12607..13071
                     /locus_tag="ACHY1N_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-fatty acyl-ACP dehydratase"
                     /protein_id="HFS4046024.1"
                     /translation="MSHYLSPGAYLPHDAPMLLLEDVVSVSDDSAVCRVTVSPSGVLA
                     PFLDPDGNLPGWFALELMAQTVGVWSGWHRHQQGKNSIELGMILGARELLCTTGILPA
                     GQTLTITVKLLMQDDRFGSFECSINDGEATGRINTFQPTAEELTTLFQQGAS"
     gene            13071..13802
                     /locus_tag="ACHY1N_003805"
     CDS             13071..13802
                     /locus_tag="ACHY1N_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase FabG2"
                     /protein_id="HFS4046025.1"
                     /translation="MSRSVLVTGASKGIGRAIACKLAADGFNIGVHYHRDATGAQETL
                     NAIVANGGNGRLLSFDVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSDD
                     DWDAVIHTNLDSFYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGI
                     IGATKALAIELAKRKITVNCIAPGLIDTGMIEMEESALKEAMSMIPMKRMGQAEEVAG
                     LASYFMSDIAGYVTRQVISINGGML"
     gene            13799..15028
                     /locus_tag="ACHY1N_003806"
     CDS             13799..15028
                     /locus_tag="ACHY1N_003806"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase"
                     /protein_id="HFS4046026.1"
                     /translation="MTRRVVITGMGGVTAFGENWQDVSARLLAYENAVRKMPEWQVYD
                     GLHTLLGAPVDDFTLPEHYTRKRIRAMGRVSQMSTRASELALEQAGLIGDPILTSGET
                     GIAYGSSTGSTGPVSEFATMLTEKHTNNITGTTYVQMMPHTTAVNTGLFFGLRGRVIP
                     TSSACTSGSQAIGYAWEAIRHGYQTVMVAGGAEELCPSEAAVFDTLFATSQHNDAPKT
                     TPSPFDENRDGLVIGEGAGTLILEELEHAKARGATIYGEIVGFATNCDAAHITQPQRE
                     TMQYCMEQSLKIAGLSAQDIGYISAHGTATDRGDMAESLATATIYGDNVPLSSLKSYF
                     GHTLGACGALEAWMSLQMMREGWFAPTLNLNKPDPNCGALDYIMHEARKVDCEFLQSN
                     NFAFGGINTSIIIKRWP"
     gene            complement(15202..15471)
                     /locus_tag="ACHY1N_003807"
                     /pseudo
     CDS             complement(15202..15471)
                     /locus_tag="ACHY1N_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167450.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15868..16899)
                     /locus_tag="ACHY1N_003808"
     CDS             complement(15868..16899)
                     /locus_tag="ACHY1N_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4046027.1"
                     /translation="MEKTRKRRGTGRVTLQEVANFAGVGTMTVSRALRTPEQVSDKLR
                     EKIEQAVEELGYIPNRTAGALASGHSHTVAVLVPSLTDKASSRFMQSLQQVLNKNEFQ
                     LLLGCHEYNQLKEAEILMTLLQGNPAALVIFGSQLADKTHQILEKTNIPTINVIGSPF
                     SPAQITIETAFFEASHKLTEHLLEQGYKNIGFIGAHMDNRLQRQQLNGWHKAMLSHYQ
                     NTDLVITMPDAASLQLGRYALNEILLRQPELDAVICSHEEIALGIMFECQRRLLKIPG
                     NIAVACLDGSDNCDQTHPTLTSIRIDYKKMGIETGKLLIGLLNNNHDESEESRIVQFN
                     YQIELRQST"
     gene            17170..17613
                     /locus_tag="ACHY1N_003809"
     CDS             17170..17613
                     /locus_tag="ACHY1N_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011192680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4046028.1"
                     /translation="MLKNLLNTEVVQVVEQVKDWREAVAISCRPLIENGSIEPRYVDA
                     IYHSHDTIGPYYVVGPGIAMPHARPEEGANKLSLALTLIPSGVNFDADENDPVKLLIV
                     LAATDSTSHIEAISQLAKLFDNEKDIQAILTAKTTQDILSVIARY"
     gene            17629..17916
                     /locus_tag="ACHY1N_003810"
     CDS             17629..17916
                     /locus_tag="ACHY1N_003810"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004717867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4046029.1"
                     /translation="MKITVVCGNGLGTSLMMEMSIKSILKDLSVSADVDHVDLGSAKG
                     TPSDIYVGTKDIAEQLAAQSVAGKIVALENMIDKKAMRERLSVVLTELGAL"
     gene            17929..19185
                     /locus_tag="ACHY1N_003811"
     CDS             17929..19185
                     /locus_tag="ACHY1N_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011815933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFS4046030.1"
                     /translation="MDFFRFLMSDVLSEPAVLVGLIALIGLIAQKKPVTECIKGTVKT
                     IMGFVILGAGAGLVVSSLGDFANIFQHAFGIQGVVPNNEAIVSVAQKSFGKEMAMIMF
                     FAMVINIMIARFTPWKFIFLTGHHTLFMSMMVAVILATAGMTGITLIAVGSLVVGVAM
                     VFFPAIAHPYMKKVTGSDDVAIGHFSTLSYVLAGFIGSKFGNKEHSTEDMNVPKSLLF
                     LRDTPVAISFTMSIIFLVTCLFAGADAVKELSGGKNWFMFSIMQSITFAAGVYIILQG
                     VRMVIAEIVPAFKGISDKLVPNARPALDCPVVFPYAPNAVLVGFLSSFAAGLIGMFTL
                     YLLNMIVIIPGVVPHFFVGAAAGVFGNATGGRRGAILGAFAQGLLITFLPVFLLPVLG
                     DIGFANTTFSDADFGALGILLGIIVR"
     gene            complement(19485..19685)
                     /locus_tag="ACHY1N_003812"
                     /pseudo
     CDS             complement(19485..19685)
                     /locus_tag="ACHY1N_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373091.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20107..21120)
                     /locus_tag="ACHY1N_003813"
     CDS             complement(20107..21120)
                     /locus_tag="ACHY1N_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFS4046031.1"
                     /translation="MSTRINLWRALFGEKPRILLENSDFTVTSFRYDSGVEGLKIANS
                     RGHLIILPWMGQMIWDAQFDGHGLTMCNMFRQPKPATEVIETYGCFAFHSGLLANGCP
                     SVEDTHLLHGEMACAAMDEAWLELDGDMLRLNGRYEYVMGFGHHYLAQPTVVLHKSST
                     LFDIKMAVTNLASVDMPLQYMCHMNYAYIPNATFSQNIPDEILRLRESVPSHVNPTAQ
                     WLAFNQRIMQGEASLSTLSQPEFYDPEIVFFADKLDAYTDQPEFRMISPDGTTFVTRF
                     YSAELNYVTRWILYNGEQQVAAFALPATCRPEGYLAAQRNGTLIQVAPQQTRTFTVTT
                     GIE"
     gene            complement(21132..22448)
                     /gene="fucP"
                     /locus_tag="ACHY1N_003814"
     CDS             complement(21132..22448)
                     /gene="fucP"
                     /locus_tag="ACHY1N_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015150 - fucose transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0015535 - fucose:proton symporter activity
                     [Evidence IEA];
                     GO_process: GO:0015756 - fucose transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HFS4046032.1"
                     /translation="MNDKNIIQMPDGYLNKTPLFQFILLSCLFPLWGCAAALNDILIT
                     QFKSVFSLSNFASALVQSAFYGGYFLIAIPASLVIKKTSYKVAILIGLTLYIGGCTLF
                     FPASHMATYTMFLAAIFAIAIGLSFLETAANTYSSMIGPKAYATLRLNISQTFYPIGA
                     ASGILLGKYLVFSEGESLEKQMSGMNAEQIHNFKVLMLENTLEPYKYMIMILVVVMVL
                     FLLTRFPTCKVAQTSHHKRPSAMDTLRYLARNPRFRRGIVAQFLYVGMQVAVWSFTIR
                     LALELGDINERDASNFMVYSFACFFIGKFIANILMTRFNPEKVLILYSVIGALFLAYV
                     ALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNEHTEMAGAVIVMAIVGAAVVPA
                     IQGYIADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRTALAEVTAS"
     gene            complement(22476..23396)
                     /gene="rbsK"
                     /locus_tag="ACHY1N_003815"
     CDS             complement(22476..23396)
                     /gene="rbsK"
                     /locus_tag="ACHY1N_003815"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFS4046033.1"
                     /translation="MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQA
                     VAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANS
                     SNSILIIKGANKFLSPEDIDRAAEDLKKCKLIVLQLEVQLETVYHAIEFGKKNGIEVL
                     LNPAPALRELDMSYACKCDFFIPNETELEILTGMSVDTYDHIRLAARSLVDKGLNNII
                     VTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAA
                     LFAAFSVTGKGTQSSYPSIEQFNEFLTLNE"
     gene            23699..24481
                     /locus_tag="ACHY1N_003816"
     CDS             23699..24481
                     /locus_tag="ACHY1N_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HFS4046034.1"
                     /translation="METKQKERIRRLIEILKKTDRIHLKDAARMLEVSVMTIRRDLHQ
                     EDEPLPLTLLGGYIVMVHKPAPSMPVIQDVPRNHRDDLPIAILAAGMVNENDLIFFDN
                     GQEIPLVISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNS
                     SPLDSLNPRKIFISASGVHDHFGVSWFNPEDLATKRKAMARGLRKILLARHALFDEVA
                     SASLAPLSAFDVLISERPLPADYVTHCRNASVKIITPDSEDE"
     gene            complement(24483..24709)
                     /locus_tag="ACHY1N_003817"
                     /pseudo
     CDS             complement(24483..24709)
                     /locus_tag="ACHY1N_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013364090.1"
                     /note="with IlvB catalyzes the formation of 2-acetolactate
                     from pyruvate, the small subunit is required for full
                     activity and valine sensitivity; E.coli produces 3
                     isoenzymes of acetolactate synthase which differ in
                     specificity to substrates, valine sensitivity and affinity
                     for cofactors; also known as acetolactate synthase small
                     subunit; frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
BASE COUNT         6256 a         6495 c         6407 g         6361 t
ORIGIN      
        1 gcactaatga aacgttatat aaaatggttt gccatcacaa tttttatcag tatgttgagt
       61 gcctgtgccc gtacggcccc agtgcaacag ataagcacca ctgtcagtgt gggtcatact
      121 caggagcagg ttaaaaatgc cattttgaaa gcaggtgcgc agcgcaagtg gattatgacg
      181 caagtgtccc ctggagttat taaagctcgc tatcaaacac gaaatcacgt tgcagaggtt
      241 cgtattacat atacagctac ctactataac atcaaatatg acagtagcct gaatctgcag
      301 gcttctgatg gaaaaattca taaaaactat aaccgctggg tgcgtaacct agataaagat
      361 atacaggtta acttatctac aggagcaacg ttatagtgat gctgatatcg ggctggaatg
      421 gcccgatagt atttaacttt ctctataaga atggttatat atgtacgaac aggacacgct
      481 cagcgcactg gatgccatca ccgaagcaca gcggattgcc tttgctccta tgcttttcca
      541 ggcagctttg tgcctgcgca atgcaggaat attagattat ttggatcaac agggtaaaca
      601 gggagctccc cttaatgcga ttactgagca cacagtcctg aatgaatatg ccgtgggtgt
      661 gttactggat atgggcttaa gcgggcgaat tattacctgt aaagagggaa tttattacct
      721 ggcgaaaatc ggtcattacc tcctgcatga cactatgact cgcgtgaata tggatttcac
      781 ccaggatgtc tgttaccagg ggctcttctt ccttgccgat tcactcaatg aaggaaaacc
      841 ttccgggtta aaagtatttg gcgactggcc gacgatatat ccggcacttt cgcaattacc
      901 agacgtcgca cgtgatagct ggtttgcgtt tgatcattac tattcagatg gcgcatttaa
      961 cgccgcactg ccttatgtat tcgccaacaa ccccacaacc ttgtacgatg tgggtggcaa
     1021 tacgggtaag tgggctttgc gctgctgcaa attcaatgaa aacatcgccg ttacgttatt
     1081 agatctgcca caacaaatcg tactggcgaa aaaaaatatc gcgaatgcag gtttttctga
     1141 tcgcatagat ttccatgcgg tggatatgct aagcgatgcc ccattaccag gcgaggctga
     1201 tatctggtgg atgagccaat ttttagactg tttttcaccc gaacaaataa ttagcatact
     1261 cagcaaaatt gccagcgtaa tgaagcctgg cgcaaaactt tgcatcatgg agttgttctg
     1321 ggatgcacag cggtttgaag cgacatcgtt tagcctgaat gcatcctcac tttattttac
     1381 ctgcatggca aacggtaaca gccgtttcta tagtgcagag aaattttacg actatctgaa
     1441 taaagcagga ttccaggtag cagagcgtca cgataattta ggcgttgggc atacactttt
     1501 gatatgccaa aagaaataat cgtcacttaa taattttggt ttaccgcggg cgcgcgttga
     1561 tgaaatttgc attaaatatt accaactggc aggcactggc gcctggactt agcgatgtgc
     1621 agcaatggca agcatggtcg cgccagccgt gggcgattga ccctgccgcg ccgttggcaa
     1681 aattaagtga actgccaatg atgaccgctc gtcgtctcag ttcaggcagc aaactggctg
     1741 ttgaatgcgg tctgacaatg ctacgccgcc atcagccaga cgctgttttg tataccagtc
     1801 gtcatggcga actggagcgc aattaccgca ttgttcatgc actggcaacc gaacaggcgc
     1861 tttctccgac ggacttcgcg ctttccgtac acaactcttc cgtgggtaac ctgaccattg
     1921 tggccaaaca gccgatcgtt tcgtcatcgc tttcggctgg tcgcgacagt ttccagcaag
     1981 gtttgtgtga agtgcttagc ctgctacaag cgggatacca gcgcgtgttg atggtcgatt
     2041 ttgatggctt tctacctgag ttttatcacc cgcaactgcc cgcagaaatg cctacctggc
     2101 cgtacgccgt cgcgctggtg attgaagctg gcgatgactg gcaatgtgaa acgcagccag
     2161 ccattgcggt aaatgaaaca acactgccgc aaagcatctt gtttttacag cactatttac
     2221 aaaatgcaga tgctttttca ctgcctggcg agcgcgtgca atggcgctgg agccgcagat
     2281 gaataagctg atgtcgcgcc tgggatgggc atggcgactg gtcatgaccg ggttatgttt
     2341 tgtcctgttt ggtctcggcg gcctgctgct ttcagtcgtg tggtttaaca tattgttagt
     2401 tttggtgtgg gatacttccc gccgccgtcg tttggcacgt cgcagcattg ccgccagttt
     2461 tcgcctgttt ttaactgtcg cgaaagggct tggcgtgctg gattatcgta ttgatggcgc
     2521 tgaaatttta cgtcaggaac gcggttgcct cgtcgtagcc aatcatccca cgctgatcga
     2581 ttacgtgctg ctggcatcag tcatgccaga aactgactgc ctggtgaaaa gcgcgctgtt
     2641 aaaaaatcct tttcttggcg gcgtcgtgcg agcggcagat tatttaatca acagcgaagc
     2701 agaaaccctg ttaccccgct gccaacagcg actggcacag ggtgacacta tcctgatttt
     2761 ccccgaaggc acacgaacga agcccggtga aaaaatgacg ttacagcgcg gtgcagcgaa
     2821 tattgccgtg cgctgcacca gcgatttacg catcgtgacg atcggctgta gcgagcatct
     2881 gctggataaa caaagtaagt ggtatgacgt cccgcctgcc aggccgtttt ttacggttga
     2941 agtccgtggg cgggtagaaa tcaataaatt ttacgatgca acttcacaag agccgacgct
     3001 ggctgcaaga cagttaaacc ggcatctttt gcttcaatta cagcaaggtt gtttacctct
     3061 atcaggaata aataatgcaa gcgctttatc tggaaattaa aaacctcatc atcagcaccc
     3121 tcaatctgga cgacttgact cctgatgata ttgatatcaa tgcgccactg tttggcgacg
     3181 gtttagggct ggactctatc gatgcactgg aactgggact ggcagtaaaa aatgagtacg
     3241 gcatcgtgct ctctgcggaa agcgaagaaa tgcgtcagca ctttttctcc gtcgccactc
     3301 tggcctcttt cattgctgcg caacgtgcct gaggaaaacc atcatgacag accaacaaac
     3361 catttatcag gaagtctcag ccctgctggt taagctgttt gaaatcgatc cgcaggacat
     3421 caaacctgaa gcgcgactgt acgaagatct ggaactggac agcatcgacg ccgttgacat
     3481 gattgtgcac ctgcaaaaga aaaccggtaa gaaaatcaag ccggaagagt ttaaagcagt
     3541 gcgtacagtc caggatgttg tcgaggctgt agaacgcctg ctacaagaag gctaatttga
     3601 tgtcgggcat tcgctcgcta ccgatgatta agttgctgac cggattattg ctgctcgtct
     3661 ggcctttttt aatctggcta ggtttggtgc ataacagcct gcactggctg ttgccgctga
     3721 tggcgctgtt gcttttattg cgcctgcgcc agccccgtcg ccagacgggg ccgctccagg
     3781 tcgtcacaaa aatcgttgct gttgtgggca ttgtattgtg tgtctccagt tttctgttga
     3841 aaacgtacca gttactgctg ttttacccgg tagtggttaa cgcagtcatg ctggcggttt
     3901 ttggcggttc gctgcggtcg acaatgccga tagttgagcg gctggcacgt ttgcaggagc
     3961 cagacctccc ggaaaaggcc gtgcgatata cccgccgcgt aacgcaggtc tggtgcctgt
     4021 tttttatttt caatggcagt attgcgttat ttaccacctt gtatggcaac atgcccttgt
     4081 ggacagcctg gaacggtatc attgcttacc ttctgatagg tttcctgact gcaggggaat
     4141 ggctgatacg tcgtaagatg atcaaacgga aaacaccatg aatcagactc tctcactttc
     4201 acagtggttg acagcctctc gccctgtaac aactcctgtt gcctggcttg gggaatatac
     4261 ctggacactg gggcatctgc ggcatgatgt agcgcttttg atcgaccatt tacgcgacca
     4321 gccaggcaat cgctgggcac tttgttttga aaacagctat ctttttattg tagcgttgtt
     4381 ggccacgcta cactcaggta aaatcccggt aatcccgggc cataatcgcg ccgctttgtt
     4441 aaatgtacaa cgctccttgt ttgattgcgt cctgagtgat aaaaggctgg gctggaacgg
     4501 tccacagttt gttgtaagca catctcacca gatgacgacc agcacgatag cctttgatga
     4561 tattgcttct gacgcgttta ttgaactttt cacatcgggt tcaaccggac aaccaaaaca
     4621 aattgcaaaa cctgttatca gccttgatca agaagcaaac atgctggcaa ctcactttgc
     4681 agaccgacta ctgggctgtc gttttgtagc atccgtgatg cctcagcacc tgtatgggct
     4741 aactttccgt atttttttac ccatggcact tggcctgcca ttgcatgccg caatgctctg
     4801 gtattctgag caacttgccg cattaagcca tacctaccgc tatgcctttg tcagcagccc
     4861 ggcgttcctt aagcgactcg accttcatct gacgcctccc ccagtggaaa tgattctctc
     4921 tgccggcggt atgctaccat ggcaggatgt agagaaaact tccacctggc tgaatatatg
     4981 gcccgatgaa atctatggta gtaccgaaac aggtattctc gcatggcgtt accgtcaaca
     5041 ggataatatc ccctggttta ctttttctga tgttcatctt tcacaggaaa gtgagggggt
     5101 tcgtgtcttt tcgccactaa tccctgctga aggattggtg cttgacgata tgttgcaatt
     5161 caatgaaaac ggtcagttcc acctgatcgg acgacgtggt cgagtggtaa aaatagagga
     5221 gaagcggata tcactggttg aaatcgaaca acgacttctg gcacttgacg gtattatgga
     5281 tgtcgctgca ataccattaa tacgcaatgg ccgccaggct atcggtgtcg tggttgtacc
     5341 aaataaagag gcccgtcaaa tatggcaatg ctccggaggg aaaactctgg agttgtcctg
     5401 gcgcaaagca ctattaccat ggcttgaacc tgttgcagta cctcgttact ggcgcattat
     5461 tgatgaaata ccagtaaaca gtatgaacaa gcgtgtctat gcgcaattac aggagttatt
     5521 tcatgatacg ccatgaaatt gagcgccatc tggttcaacc gcaggagatg gaaatcgttc
     5581 tataccttga cccgatgctc tactggttta atggtcattt tgccgtacag cctctgttac
     5641 caggcgtggc ccagttggac tgggtaatgc attatgctac cacgctgctt gctccgggct
     5701 ggcgttttcg tagtatccag aatgttaaat ttctggcgcc acttatacct gagacgactg
     5761 ttaccctgca attaacatgg caggaaacaa gtcaggtact cactttctgc tatcagcgtc
     5821 acgacggtga cgcccgccac accgccagta gcgggaagat ccgtctatgt cggtaaactt
     5881 ttctccctgc gtgttgatcc cctgctacaa ccacggcgcg atgatgccgg gcgtgctggc
     5941 gcgtcttaag ccatttaatc tgccctgtat tgtggtggat gacggcagcg atgccgccac
     6001 gcaacagcaa ctggataatc tggttagcga acagcctggc gtgaccttaa ttcgcctggc
     6061 agaaaacgca ggtaaaggcg cagcggtgat gcgtggcttg caggcagcgg cagacgcagg
     6121 gttcagccat gcggtgcagg tggatgctga cggtcaacat gcgattgaag atatccccaa
     6181 actgctggca ctcgctgaac aacaccctgt ggcgctgatc tccggtcagc caatttacga
     6241 tgactccatt ccccgctcac ggctgtacgg gcgctgggtc acccacgtct gggtatggat
     6301 cgaaacgctc tccctgcaac tgaaagacag catgtgcggt tttcgcgttt atccggttgc
     6361 gccgacgctg caactggcaa aacgcgccac catcggcaag cggatggatt tcgacaccga
     6421 agtgatggtg cgcctctact ggcagggaaa taccagctat ttcgtgccga cccgcgtcac
     6481 ctatccactg gacgggcttt cgcattttga tgccctgaaa gataacgtcc gcatctcgct
     6541 catgcacacg cgtctgtttt tcggcatgtt gccgcgtatt ccttcactgc tgatgtgcca
     6601 ctcttccagc cactgggcgc ggcagagtga agttaaaggg ttatggggaa tgcgcctgat
     6661 gctgctggtc tggcgtctgc tgggaagaac ggcgtttacc gcgctgcttt acccggtggt
     6721 tggcgtctac tggctcaccg ctgctcgtgc gcgtaaagcg tcgcaagact ggctcgcccg
     6781 tgtgcgccaa caacaaccac aggcagcaaa aatcaacagc tatcagcact ttctacgttt
     6841 cggcaacgcc atgctcgaca aaatcgccag ctggcgcggc gagctgcaac tcgggcgtga
     6901 tgtgctgttt gcgccaggcg cagaagcggc gcttgacgtc cgcgatccgc gcggcaaatt
     6961 gctgctggcc tcacatcttg gcgatgtgga agtgtgccgg gcgctggcaa aaattgaggg
     7021 ctacaaaacc attaacgcgc tggtgtttag cgaaaacgcc caacgcttta aacagataat
     7081 gcaggagatg gctccccagg caggcattaa cctgatgccg gtaacagata tcggcccgga
     7141 aaccgccatc ctgctgaaag agaagctgga taacggcgaa tgggtggcga ttgtcggtga
     7201 ccgcatcgcc gtcaccccgc aacgcggcgg cgactggcgc gtctgctgga gtccgtttat
     7261 gggccagcct gcgcccttcc cacaggggcc gtttattctc gcctctattt tgcgctgccc
     7321 ggtgaatctg attttcgccc tacgccagca cggcaagctg catattcact gcgaaacctt
     7381 tgccgacccg ctgctgttgc cgcgtggcga acgccaacag gcgctgcaaa acgctatcga
     7441 ccactacgcc gcgcgtctgg aacattacgc gctccagtcg cccctcgact ggtttaattt
     7501 tttcgatttc tggcaactgc cggaaattca ggacaaggag taaagggtgc ttaacgatcc
     7561 ccgatttacc gctgaagtcg agctgaccat tccctttcac gacgtcgata tgatgggcgt
     7621 ggcctggcac ggtaactatt ttcgctactt tgaagtggcc cgcgaggcgc tgctcaacca
     7681 gttcaattac ggctatcggc agatgaaaga gtccggttat ttgtggccag tggtcgatgc
     7741 gcgggtgaaa tatcgccacg ccctcacctt tgagcaacgc atccgcgtgc gtgcgcatat
     7801 cgaagagttc gaaaaccgtc tgcggattgg ctatcagatt ttcgatgccg aaacgggcaa
     7861 acgcgccacc accggataca ccattcaggt cgcagtcgac gagcaaagcc gcgaactgtg
     7921 ctttgtcagc cccgatattc tgtttgaacg catgggagtc aaaccatgaa atttttaccg
     7981 ctgctggcgc tgctgattag cccgtttgtg agcgccctga cccgggacga tcttcagcaa
     8041 cgctttaccg aacaaccggt gatccgcgcc catttcgatc aaacccggac gattaaagat
     8101 ctgccgcagc cgctgcgatc tcagggtcag atgttgatcg cccgcgacca ggggttattg
     8161 tgggatcaaa cctcaccgtt ccccatgcaa ctattactgg acgataaacg catggtgcag
     8221 gtgatcaacg gtcagccgcc gcaaatcatc acggcagaaa acaacccaca gatgttccag
     8281 tttaaccacc tgctgcgcgc gctgttccag gccgatcgca aagtgctgga acaaaacttc
     8341 cgcgtcgaat ttgccgacaa aggcgaaggc cgctggacgc tgcgcctgac gccgaccacc
     8401 acgccgctgg acaaaatttt caacaccatc gatctcgccg ggcaaaccta tctggagagc
     8461 attcagctta atgataaaca gggcgatcgc accgatatcg ctcttaccca acatcaactg
     8521 acaccagcgc aactgaccga tgacgaacgc caacgctttg ccacccagta aacgccccgc
     8581 gctgttatgg gggctagtct gcctggtcat ggcggcggcg ttgctgatcc tgctgccaca
     8641 atcacgactg aacagtagcg tgctggctat gttacccaaa caggcgatgg gcgatattcc
     8701 tccggcgctg aatgacggct ttatgcagcg tctggaccgc caactggtgt ggctggtcag
     8761 ccccggtaaa gaggctaatc ccagggtggc tcaggagtgg ctgacgctgc tgcaaaaatc
     8821 cgctgcgctc ggcgacatta aagggccaat ggatgccgcc agccagcagg cgtggggagc
     8881 gtttttctgg cagcaccgca acggcctgat tgaccccgac acccgcgccc gcctgcaaaa
     8941 tggcggcgaa gcgcaggcga agtggatcct ctcccagctt tattctgcgt tctccggggt
     9001 aagcggcaag gagctgcaaa acgatccgct gatgttaatg cgcggctcgc agctggcgat
     9061 ggcgaaaaat ggccagcgtt tacgactaat ggacggctgg ctggtgacgc aggatcccca
     9121 gggccattac tggtatctgc tgcacggcga actggcggga tcgtcgtttg atatgcagca
     9181 aacccaccag ctcatcacga ccctgaatac gctggaaaag gctctgaaaa cgcgttaccc
     9241 gcaggcgcag ttgctctcac gcggcacggt gttttacagc gattacgcca gccaacaggc
     9301 gaagcaggat atctccaccc tgggcgtggc aacgctgctg ggggtgatat tgctgattgt
     9361 ggcggtgttc cgctctttgc gcccgttgct gctttgcgtg atttccatcg gcatcggcgc
     9421 gctggcggga acggccgcca cattgttgat tttcggtgaa ttacacctga tgacgctggt
     9481 gatgagcatg agcgttatcg gcatttccgc tgactacacg ctctattatc tcaccgagcg
     9541 gatggtgcac ggcaacgacg tttcgccgtg gcaaagcctg gcgaaagtac gcaatgccct
     9601 gctgctggcg ctgctcacaa ccgtggcggc atatctgatt atgatgctcg cccccttccc
     9661 cggcattcgc cagatggcga tttttgccgc cgtcgggttg agcgcctctt gtctgaccgt
     9721 cctgttctgg catccgtggc tgtgccgtgg tctgccggtg cgcccggttc cggcgatggc
     9781 gctgatgcta cgctggctgg cagcgtggcg gcgcaataaa aaactgtcgc ggggtctgcc
     9841 cgttgcgctg gcgctgtttt cgctggcggg gatgtcaatg ctgcgcgtcg atgacgatat
     9901 ctcgcagtta caggcgctgc cgcagcacat tctggcgcag gagaaagcca ttaccgccct
     9961 gaccggacaa agcgtcgatc aaaaatggtt tgtagtttac ggcgactccc cacagcaaac
    10021 attgcggcga ctggagaaat ataccgcctc acttgagtat gcgaaaaaag aggggcttat
    10081 cagcaactac cgcactattc cgctgaactc cctggcgcgg caggaggaag acttagacct
    10141 gctgaaaacg gctgccccga cggtaacaaa agcactgcaa aatgcagggc tgacggcggt
    10201 gaaaccagat ctcaacgcca tgccggtgaa ggtcgatgaa tggctggcaa gccccgccag
    10261 tgaaggctgg cgtctgctgt ggctgacgct ggaaaacggc gaaagcggtg tactggtgcc
    10321 ggttgaaggg gttaaaagta gcgcattgtt gcaggaaatc gccagctatt acccttgcgg
    10381 cattgcctgg gttgatcgca aaagctcctt tgatgaattg ttcgcacttt accgctacgt
    10441 cttaaccggc ttgttgctgg tggcgctggc agtgattgcc tgcggcgcag tggcccgtct
    10501 cggctggcgc aaagggctta tcagcctggt gccttcggtg ctttcgctgg gctgtggtct
    10561 ggcggtgctg gcgatgagcg ggcaggcggt gaatctcttt tcgctgctgg cgctggtgct
    10621 ggtgcttggc atcggtatca actacacgct gtttttcagt aatccgcgcg gtacaccgtt
    10681 aacttcgcta ctggcgatcg cgctggcaat gctcaccacc ttgctgacgc tgggaatgct
    10741 ggtattcagc gccacccagg ccatcagcag ttttggcatt gtgctggtga gcggtatttt
    10801 caccgccttc ctgctttcgc cgctggctat gcccgataaa aagagaacaa aaaaatgatc
    10861 aaatccacat tctggcgagc gttcgccctg accgctacgc ttatcctcac cggctgtagc
    10921 cactcgcaac cagaacagga aggccgcccg caggcgtggc tgcaacctgg cacgcgcatc
    10981 acgctgccgg caccagggat ttcacccgca gtcaattcgc agcaactgtt gaccggcagc
    11041 ttcaacggca aaacccagtc gctgttagtg atgcttaacg ccgacgatca gaaaatcacc
    11101 cttgccgggc tgtcgtcggt cggcattcgc ctgtttctgg tgacctacga tgcgcaaggg
    11161 ctacgcgccg agcaatccat cgtcgtccca cagttaccgc ccgcaagtca ggtactggct
    11221 gacgtgatgc tcagccactg gccgattagc gcctgggagg cgcaacttcc cgcaggatgg
    11281 acacttcgcg acaacggtga caaacgcgag ctgcgtaaca ccagcggcaa actggtcacg
    11341 gaaatcacct atctgaatcg ccagggaaaa cgcgtgccaa tcagaattga gcagcatgtc
    11401 tttaaatacc acatcaccat tcaatactta ggtgactgat atgatttata tttccgccgt
    11461 cggcatgatc aacgccctgg gaaataacct tgacgaaatc gcagccaact tggctcgcgg
    11521 tgtcgccccc ggcatgcgcc cacgcgcagg ctggttgcag gggcatccgc aggcggtcct
    11581 ggctggcgtg gatggcgagc ttccgcttat cccggaaaaa ttcgctgcgc atcgctcgcg
    11641 caacaatcag atcctgctgg cggcgctggc gcagctccag ccgcaggttg atgacgctat
    11701 cgcgaaatat ggctgcgagc gcatcgcgat tgtgcttggc accagcacct ccggcctgca
    11761 tgaaggcgac acgcacgtta acctgcacac ccacgggcag ccgaacacca cgtggcacta
    11821 tgcacaacaa gaactcggcg atccgtcgcg ttttctcagc cactggctgg cgctcgacgg
    11881 cccggcttat accctttcaa ccgcctgctc ctccagtgcc agagcaatga tcagcgggcg
    11941 caggcttatc gaagcggggc tggtcgatgc cgccattgtg ggtggcgcag acaccctgag
    12001 ccgaatgccg attaacggtt ttcacagcct cgaatcgctc tcgccaacct tatgtcagcc
    12061 gtttagtcgt gaccgcgcag gtatcaccat tggtgaaggg gcggggctaa tgctgctgac
    12121 ccgggaaccg cagcccatcg cgttgctggg cgttggtgaa tcgagcgacg cttaccatat
    12181 ttcagccccg catccgcagg gcgaaggagc gatccgcgct attaatcagg cgctgaccga
    12241 tgcgcagctt acgccggatg acgtcggcta tatcaacctg cacggcaccg ctacacagct
    12301 caacgaccag attgaatcaa tggtggttaa cgccctgttt ggcgaacgcg taccgtgcag
    12361 ctccaccaaa catttgaccg gacacacgct cggcgcggct ggcattaccg aggcggcaat
    12421 tagtatgttg attttacagc gtgatttacc gctgcccgct caggacttca gcctgtcgcc
    12481 gcgcgatccc acgctgccac cgtgtggcat tatcgaaaaa ccgcagccgc tggcacgtcc
    12541 ggtgatcctg tccaattcct tcgcctttgg cggcaataac gccagcattc tgctcgggag
    12601 ggtttcgtga gccactattt atcccccggc gcttatctgc cccacgacgc gcccatgtta
    12661 ctgctggaag acgtggtgag cgtcagcgat gacagcgcgg tgtgccgcgt gacggtttcg
    12721 cccagtggcg tactggcacc gtttctcgac ccggacggca atctccctgg ctggtttgcc
    12781 cttgaactga tggcgcaaac cgtcggcgtc tggtctggct ggcatcgcca ccagcagggc
    12841 aaaaacagta ttgagttagg gatgatactg ggcgcgcgtg aattgctttg caccactggc
    12901 attctgcccg caggccagac gctgaccatt accgtcaaac tgctgatgca ggacgatcgc
    12961 ttcggcagct ttgagtgcag catcaacgac ggcgaggcga cgggccgcat taacaccttc
    13021 cagccgaccg cggaagaact taccaccctg tttcaacaag gagcgtcctg atgagtcgtt
    13081 cagttctggt tactggtgcc agcaaaggca ttggtcgcgc catcgcctgc aagcttgcgg
    13141 cagacggctt taacattggc gttcactatc accgtgacgc cacaggcgct caggaaacgc
    13201 tgaatgccat tgtcgccaac gggggtaacg ggcgtttgct cagtttcgac gtcgcaaacc
    13261 gcgaacagtg tcgggaagtg ctggagcatg agatcgcgca acacggtgcc tggtacggcg
    13321 tggtcagtaa cgccgggatc gcccgcgatg ccgcttttcc ggctttaagc gatgacgact
    13381 gggatgcggt gatccacacc aacctcgaca gtttctacaa cgtcattcag ccgtgcatta
    13441 tgccaatgat cggcgcgcgc cagggtgggc gcatcatcac gctgtcctcg gtttccggcg
    13501 taatgggcaa tcgcggccag gtgaattaca gcgcagccaa agccggaatt atcggcgcaa
    13561 caaaagcact ggctatcgaa ctcgcaaagc gcaaaatcac cgtcaattgc atcgcgccag
    13621 ggcttattga taccgggatg atcgaaatgg aagaaagcgc tctgaaagag gcaatgtcga
    13681 tgatccccat gaaacgtatg ggccaggcgg aagaagttgc cgggcttgcc agttatttta
    13741 tgtctgatat tgcgggttac gtcacccgcc aggttatttc catcaacgga gggatgttat
    13801 gacacgtcgc gtagtgatta caggaatggg cggcgtgact gcctttggtg aaaactggca
    13861 ggacgtttct gcacgcttac tggcgtatga aaatgcggtg cgcaaaatgc cggagtggca
    13921 ggtctacgat gggctgcaca ccctgcttgg cgcgcctgtt gatgatttca cgctaccgga
    13981 gcactacacc cgcaagcgta tccgtgcgat gggccgcgtg tcgcaaatgt cgacccgtgc
    14041 cagcgagctg gcgttagagc aggcagggtt gattggcgat ccgatattaa ccagcggcga
    14101 aacgggcatt gcgtacggtt catcgaccgg cagtaccggt ccggtgagcg aatttgccac
    14161 catgctgact gaaaagcaca cgaacaacat cactggcacc acctatgtgc agatgatgcc
    14221 gcacaccacc gctgttaata ctggcctctt tttcggcctg cgcgggcggg tgatcccaac
    14281 ctccagcgcc tgtacctccg gcagccaggc gatcggttat gcgtgggaag ccattcgcca
    14341 cggttatcaa acggtgatgg ttgccggtgg tgccgaagag ttatgccctt cagaagcagc
    14401 agtgtttgat accctttttg ccaccagcca gcacaatgat gcgccgaaaa ccacaccttc
    14461 accgttcgat gaaaaccgcg acggactggt gattggtgaa ggcgcaggta cgctcattct
    14521 cgaagaactg gagcatgcca aagcgcgcgg cgcgaccatt tacggtgaaa tcgtcggctt
    14581 tgcgacgaac tgcgacgcgg cacatattac ccagccgcag cgcgaaacca tgcagtattg
    14641 tatggagcaa tcgctgaaaa tcgcagggtt aagcgcacaa gatatcggct atatttcagc
    14701 gcatggtacg gcgaccgatc gcggtgatat ggcagaaagt ctggcgacag caaccattta
    14761 cggtgataat gtgccgctct cctcgctgaa aagttatttt ggtcatacgc ttggtgcctg
    14821 tggcgcgctc gaagcctgga tgagtctgca aatgatgcgc gaaggttggt ttgcgcctac
    14881 gctaaacctg aataaaccag acccgaattg tggcgcgctg gattacatca tgcatgaagc
    14941 ccgcaaggtt gattgtgagt ttttgcagag taacaacttt gcctttggcg gcattaatac
    15001 atccatcatt attaagcgct ggccctgagt tatacaacca catggacatc ccatgtggtg
    15061 attcttcaaa aaatctgaat caatgaatat gaacctcaaa ttctcttacg catactgaag
    15121 agcattccgt ataacgattc agcagacaaa actttatcag tccacacgaa tcaacggatg
    15181 cacagatgac acgcccggtt atcaccgggc aatggttgcc ataacgggta acataaggga
    15241 ctgaacagtt gtctttagcg caacgaactg atctaacgta cctgaacgga caacctgaaa
    15301 acagccttcc atcctgcatt gtccgccagt gcttattacc aaccacgtct gttgcagtaa
    15361 agtaatcagt tgcgaacatt atttatcaat cgtgacgctg gctcgcgcat ggcagaaaag
    15421 gtcctgactg agcaacaaca ggcatcgtac tgttgctgct ccatgttgtt tatatgaacg
    15481 catcccgttt gcaaggcttc cgtgtttttg acgttgacgg tagattgctg ctctatatcc
    15541 ttattgcagc cggtgctgcg ggcctcaatg agattcgctg actctcgcct tattcacgca
    15601 acgagcttta agctcagaaa aacatccaag tttggtgagt cacagtctta cctgtcgttg
    15661 tcatcaatat aggaatggat aatctggaga gcgatactgc aggctgatat tgcggttttg
    15721 cgacaagttt ttagcatccg cttctacgcc aaatacctga agtaggaatg gatgcgttag
    15781 cagcatacat ccggaactgc gcggggaata gccggaaacg gctatcccta ccacaatagc
    15841 taactttgta atatcgctct tttaggctca tgtactctga cgtaattcta tctggtagtt
    15901 gaattgcacg atacgcgact cttctgattc atcatgatta ttattcaata gtccaatcag
    15961 taacttacct gtctctatcc ccattttttt gtagtcaata cggatggatg tcaaagttgg
    16021 gtgtgtttga tcgcaattgt ctgaaccgtc aagacaagct acagcgatat ttccagggat
    16081 ttttaacaaa cgccgctggc actcaaacat tatacccagc gcaatctctt cgtggctgca
    16141 aatcacagca tccagctctg gttgtcgcag taatatctcg tttaatgcgt aacgccccaa
    16201 ttgcagactt gcggcatccg gcatggtgat aacaagatca gtgttctggt aatggctcag
    16261 cattgcttta tgccagccgt tcagttgctg acgttgcagg cggttgtcca tatgcgcacc
    16321 gataaatccg atattcttat aaccctgctc cagcagatgt tcggtcagtt tatgtgatgc
    16381 ttcaaaaaat gctgtttcga tggtaatttg agccggactg aaaggggaac cgataacgtt
    16441 aatggtaggt atatttgttt tctcgagtat ctggtgagtt ttatcagcca actgagaacc
    16501 aaaaataact aacgccgccg ggttgccttg aagaagcgtc atcagaattt cagcttcttt
    16561 gagctgatta tactcatgac acccaagcag tagttggaat tcatttttat taagcacctg
    16621 ctgtaatgac tgcataaagc gggagctggc tttatctgtc agggaaggaa ccagtacggc
    16681 gactgtatga ctgtgaccag atgcaagggc gccagcagtt ctgttgggaa tataacccaa
    16741 ctcttctacg gcctgttcta tcttttccct cagcttgtca gaaacctgtt ccggtgttct
    16801 cagcgcgcgg gaaacggtca tagttccgac acctgcaaag ttagcgacct cctgcagcgt
    16861 cacccgtccg gtaccacggc gcttacgtgt tttttccatt tcgactccat ggataattac
    16921 aaccagctgt tttcattact tttatttcac cattactctt tccagttttt gcccacggta
    16981 gcaaatatcc tgttgcattg tatatgcagg aaccgaatat agccaaagca tggcggcaga
    17041 gaaatgatag cgctatcaca aagattggta gcgttatcag atagcgctat caaatgcgac
    17101 aatcatcaca ttaattaatg cgtaaaatat ctactctcct gttaattatc atcgggagtt
    17161 atcagtagca tgttaaaaaa tctattaaat acagaggtcg ttcaggtcgt ggaacaggtc
    17221 aaagactggc gggaagccgt ggcgatttca tgccgaccgt tgattgaaaa cggctctatc
    17281 gaaccgcgtt atgttgatgc gatctatcac tcgcacgaca ctatcggtcc gtactatgtg
    17341 gttggccctg gtattgcgat gcctcatgcg cgcccggaag agggggctaa caagctgtca
    17401 ttagcactga ccctgatccc ttcaggtgtg aattttgatg ccgatgaaaa cgatccagtg
    17461 aaattactga ttgtgctggc tgcaaccgac agtaccagcc acattgaagc gatttctcaa
    17521 ctcgccaagt tattcgataa cgaaaaagac atacaggcca ttttgacggc caaaacgacg
    17581 caggacattt tgtctgttat tgcgcgctat taatccagag gaacatttat gaaaattaca
    17641 gtggtttgcg gtaacggctt aggcaccagc ctgatgatgg aaatgagcat taaaagcatt
    17701 ttgaaggatt tgtccgtcag cgctgatgtt gatcacgtcg acctgggctc cgcgaaaggg
    17761 acgccgagtg atatctatgt cggcaccaaa gacattgccg agcagttagc cgcgcagtct
    17821 gtcgcaggca aaatcgtcgc actggaaaat atgattgata agaaagccat gagagaacgt
    17881 ttgtccgtgg tattaaccga attaggcgca ctgtaagctg ggggcgatat ggatttcttt
    17941 cgttttttga tgagcgatgt actttccgaa cccgcagtgc tggtcggttt aatcgccctg
    18001 attggcctga ttgcacagaa aaaaccggta accgaatgca ttaaaggtac cgtcaagacc
    18061 attatggggt ttgtgatttt aggcgcaggg gcgggtttag ttgtgtcgtc actgggtgac
    18121 ttcgcaaaca ttttccagca tgcctttggt attcagggtg tagtgccgaa caatgaagcc
    18181 attgtttccg tagcgcagaa aagcttcggg aaagaaatgg cgatgattat gttctttgcg
    18241 atggttatca acattatgat tgcccgtttc acaccgtgga aatttatctt cctgaccggt
    18301 catcacacgt tgtttatgtc gatgatggta gcggtaattc tggcaacagc aggcatgacc
    18361 ggcattacgc ttatagccgt tggctctttg gttgttggcg tggcaatggt ctttttcccg
    18421 gctattgcgc atccgtacat gaagaaagtg accggttctg atgacgttgc catcggccac
    18481 ttctcaacat tatcttatgt attggccggt ttcatcggca gcaagtttgg taataaagag
    18541 cactcgactg aagacatgaa tgtgccgaaa agtctgctgt tcttgcgcga cacgccggtt
    18601 gctatctctt ttaccatgag cataattttc ctggtgacgt gcctgtttgc gggtgcagat
    18661 gcggtgaaag agcttagcgg tggtaaaaac tggttcatgt tctctatcat gcaatccatt
    18721 accttcgcag ctggcgtgta catcattctg cagggtgtgc gcatggtgat tgcggagatt
    18781 gtcccggcat tcaaaggtat ttcagacaag ctggttccga atgccagacc tgctctcgat
    18841 tgcccggtcg tcttccctta cgcacctaac gctgtactgg ttggtttcct gagtagcttt
    18901 gctgcaggtt taatcggtat gttcacgttg tatctgctga acatgatcgt gattattcct
    18961 ggtgtggtgc cgcacttctt cgtaggtgca gctgcagggg tattcggtaa tgcaacgggt
    19021 ggacgtcgtg gtgcgatttt gggtgccttc gctcagggct tgcttattac cttcctgcca
    19081 gtattcttat tgccggtgct gggtgatatt ggttttgcta acaccacctt cagtgatgct
    19141 gactttggcg cactgggtat tttgttaggg attatcgttc gctaatattt tgatgacatt
    19201 aatatcctcc aggatttcag gaacgtggag gatattaatt cctcttattt tctccatttt
    19261 tctttcttcc agtcaggact gcatccgatt aatcgtaagc gctccgagaa gtacgtagcg
    19321 taaggattat tttacagctg agaagtttca gtgcagcagt tcatgcacac ggttcgacgg
    19381 ctagtcattg atcttcataa ttacctcgcg taaaaaacgg ggtaaggccg ctcatccagc
    19441 gtcatctcca caggtaataa ttcaacgcca atgccagaag agttcgttac cggaagacgc
    19501 cgtgatatac gccctttgat cagcgagagc ctgagccatt tgaacagaag attatcattg
    19561 atatcatgct cccgggcaat acgggcaaca gaaccccttg gttgtaaagc cagtttaacc
    19621 atttgaagtt taaactcatt tgaaaatgac ctgcggggtt caactgataa tgttttttgt
    19681 tccataacag gtgtccacta gttgaaaagg tgggtaccta tgttaccaat actggcttaa
    19741 tggctacata cagcagtcgg tttacgcata cacttttata gtgcactccg gcctcatgaa
    19801 tataacggtg gattaccgcc gaacgaatcg gaaaatagat actggaaaaa aactgaaatt
    19861 gtgaccagtt tttgttgacc actacaaata aataaaagag ttgcagtgct tgctcggtaa
    19921 gaaaacaatg gaggttaagc tcctcaaaga agctgtggag tacaccactc tacagtagtt
    19981 gcgcaaattt ggagtggacg ataatgtgat cgtctataag ggcaacgcta tcatagtctt
    20041 gtcctggcgg gtaaaaaaac gcgcttacct taacgataag cgcgccgctg ttcaggcctt
    20101 gagtggttat tcaattcctg tggtgactgt aaaagtgcgc gtttgctgcg gtgcaacctg
    20161 aatcagcgtg ccattacgtt gcgcggcaag atacccctca ggccgacagg ttgcaggtaa
    20221 tgcaaaggcg gctacctgtt gctctccgtt ataaaggatc cagcgtgtca cataatttag
    20281 ttcagcactg tagaaacgag taacaaacgt agtgccatcg ggagagatca tgcgaaactc
    20341 tggctgatct gtataagcgt ccagtttgtc tgcaaagaag acaatttctg gatcataaaa
    20401 ttccggttga ctcagcgtcg acagagaggc ttctccctgc ataatccgtt gattaaacgc
    20461 cagccactga gcggtgggat taacatgcga aggcactgat tcacgcaatc ttaatatttc
    20521 gtccgggata ttctggctga atgtagcatt tggtatatat gcataattca tgtggcacat
    20581 atattgtagt ggcatatcta cagaagccag attggttacg gccatcttaa tatcgaacag
    20641 tgtagaggat ttgtgaagga ccactgttgg ctgagccaga taatgatgac cgaaacccat
    20701 tacatactcg taacgcccgt taaggcgtaa catatctccg tctaattcca gccatgcttc
    20761 atccatcgcg gcacaggcca tttcaccgtg tagcagatga gtatcttcca cagatgggca
    20821 gccattagcc agcaaacctg aatgaaaagc aaaacagcca taggtctcta tcacctctgt
    20881 cgccggttta ggctggcgaa acatattgca catggtgagg ccgtgtccat caaattgcgc
    20941 atcccaaatc atctgcccca tccagggaag aataatcaaa tgtccacgac tgtttgcaat
    21001 tttaagcccc tcgacaccgc tgtcatatcg aaaagacgtg acagtaaaat cactattttc
    21061 cagcaagata cgaggtttct cgccaaaaag cgcccgccac aaattaatac gcgtactcat
    21121 aacgattctc ctcaggacgc tgtgacttca gccagtgcgg tacgtacttt gctttcacgc
    21181 cagaagtaga ctccgacata gacaaagcag agcatagaaa ccaggaatga aagctgtagt
    21241 gagtggaaca tatctgcaat atatccctga attgccggaa ccaccgcggc accgacaata
    21301 gccataacaa tgactgctcc tgccatttct gtatgttcgt tatcaactgt atccagtgtt
    21361 cctgcataga tcgtcgccca gcaagggcca aacaaaacac ttaccaggac ggcgacatag
    21421 accgcgctga aacttggagc cagtgcaaca tatgccagga acagcgcccc tataacggaa
    21481 tagagaatca atactttttc cggattaaaa cgcgtcataa ggatattggc tataaacttg
    21541 ccaataaaga agcaggcaaa gctatagacc atgaagtttg aagcatcacg ttcgttgata
    21601 tcgcccaact ccagcgccag acggatggta aatgaccata ctgcgacctg catacccaca
    21661 taaaggaact gcgccacaat accgcgacga aagcgcggat ttctagccag atagcgcagc
    21721 gtatccattg ctgacgggcg tttatggtga cttgtctgtg ccactttaca ggttgggaag
    21781 cgggttaaaa ggaacaacac catgaccaca accagaatca taatcatata cttatacggt
    21841 tcaagggtgt tctctaacat cagcacctta aagttgtgaa tttgctcggc gttcattcct
    21901 gacatctgct tttcaaggct ttccccctcg gagaaaacca gatatttgcc caataaaata
    21961 ccagacgcag caccaatcgg ataaaaggtc tggctgatat tgagccgcaa tgtggcatag
    22021 gcttttggac cgatcattga actgtatgtg ttcgctgcag tttcaaggaa actcaggcca
    22081 atcgcaatcg caaaaatagc tgcaaggaac atagtgtagg ttgccatatg cgaggcaggg
    22141 aaaaaaagtg tacaaccacc aatatacagc gtcaggccaa ttaaaattgc caccttataa
    22201 ctggtctttt taatcacaag ggatgctggt attgcaatta aaaaataacc tccataaaat
    22261 gcgctctgca ccaatgctga agcaaagtta cttagcgaaa atacactttt gaattgagtg
    22321 attaatatgt catttaatgc agctgcgcat ccccatagcg ggaataaaca cgataacaaa
    22381 ataaactgga acaagggagt cttattcaga tacccatcag gcatctgaat gatgttttta
    22441 tcgttcatag tgctaccttt aactgtgcag gatgattatt cgtttaaggt taaaaattca
    22501 ttaaattgtt caatactcgg ataagatgat tgcgtacctt tccctgtgac gctgaaagcg
    22561 gcaaagagag cggctttttt caaagcggct tcaacatcac cgctttgaac ataataatgg
    22621 gaaaagcaac caataaatgc gtcaccagcg ccactagtat caacagcatt tactttgaat
    22681 gcaggaacat ggacttcctg atcgcgggtc atccataatg cgcctttttc gctcatggta
    22741 acaataatat tgttcagccc tttatcaact aacgaacgtg cggccaaacg aatatgatca
    22801 taagtatcaa ccgacatacc ggttaatatt tccagttctg tttcattcgg gataaagaaa
    22861 tcacatttgc aggcataaga catatctaac tcacgcaatg ccggagccgg atttaataac
    22921 acttcaatac catttttctt accaaactca atcgcgtggt aaactgtttc cagttgaact
    22981 tccagttgta aaacgatcaa tttgcatttt ttcagatctt ctgcagctcg atcgatatct
    23041 tccggggaaa gaaatttatt cgctccctta attattaata tactattgct cgagttggca
    23101 ttaacaaaga tcggtgcaac accactgctg gtacagggga ctttctcaac ataagtggta
    23161 ttaattcccc atgattcgag attacgaata gtattatccg caaaaatatc atcacctact
    23221 ttagtcagca tcaggacttt tgaattcaat ttagccgccg ccaccgcttg attagcacct
    23281 ttcccaccac atccgatttt gaaggcaggt gcttccagag tttctccttc tttaggcatc
    23341 tgattagtgt aagtaatgag atccaccata ttggaaccaa taactgcaat gtccatttca
    23401 ctacctctta taaactttcg cataacaatg gtatttaaat aacattaaca tgttactttt
    23461 gcatcatttg tgactgagat cgcgattagc acatcaaccc gatgtttatt taatagactt
    23521 ccagtcttat cactcaggcc aacactatct aatcataagc aacctaacag gattaatacc
    23581 gaaaattcag cagtctatac ccttttcatt tcaaagggtc ggtcgtatag tatggtaact
    23641 aaaacaatgt ttactaatgc cataatgtta tttttataac attttacgga gagagttgat
    23701 ggaaacgaag caaaaagagc gtatccgacg tttgattgaa atacttaaga aaaccgacag
    23761 aatccatttg aaagacgcgg cacgaatgct ggaagtttct gtaatgacta ttcgtcgcga
    23821 tctccatcag gaagatgaac ctctgccact gaccctactg ggtggctata ttgtaatggt
    23881 gcataaaccc gcaccatcca tgccagtaat ccaggacgtt ccgagaaatc atcgtgatga
    23941 cttacctatt gcaattctgg ccgccggaat ggttaatgaa aatgatctga tcttctttga
    24001 taatggccag gagataccgc tcgttataag catgatcccg gatgcaatca ccttcactgg
    24061 catctgttac tcacatcgtg tctttgttgc gttgaatgaa aaacctaatg tgacagcaat
    24121 actttgtggt ggtacgtatc gtgccagaag tgatgctttt tacgatgcca gtaactcttc
    24181 gccattagac tctctcaatc cgcgaaaaat atttatttcc gccagcggtg tacatgatca
    24241 ctttggcgtc agctggttta atcccgaaga tcttgccact aagcgtaaag cgatggcccg
    24301 tggactaagg aaaattttgc tcgcccgcca cgccttgttc gatgaagtag cctctgccag
    24361 cctcgcaccg ctctctgcat ttgatgttct gattagcgag cgtccgttac cggcagatta
    24421 tgttacgcac tgccggaatg cttctgtaaa gatcattaca cctgattcag aagacgaatg
    24481 acttactgaa aaaacaccgt actcttgtta aacatcgtcg gattggactg attacgttgc
    24541 actttcatca catattccag tttatcaatt tggcttatca tctactccag acgctggtca
    24601 tcattgacca atagtctgat atggcttttg tcgctgtcct gaatcggcag gcagaaaatg
    24661 ccttcaacgt taaaagcacg acgggaaaaa gcccacaaag gttagtcatt acgcccggat
    24721 aataaacagg ctcctccctg ttatggaagc cgttgtattg tccataatgt ctgggttttt
    24781 aatgcacact ggataacaac cggacgaatc ttcaaatatt actggcgctg acagccggtt
    24841 tgaattcatc tcacaaccct gcatagagcg aatctcctgc ctgcacgtca ctccactcca
    24901 tggtatcaac ttcacactct ttatctgcgg ctagtttcag tcaccagata agcatcgact
    24961 atgaaaggtg agccatgaca acataacgtt ggtaacgctc tgacgcctta acggaagatg
    25021 cctgccacca cagggaatgt aaacgactga agtgtggcct ttaatgccgt gaacggctca
    25081 tggtctcctg gcacggttgc cgccccaacc tgtaacaaca ttccacagta caatgtctgt
    25141 cagagccgga gcctcccatg cctgttgaat aaaaccccgg atgcttcccc cgattctgca
    25201 agtaatactt cggttattta cactatttta tccctgttga atttggttaa gccggtgcag
    25261 acgcgccggg aaacgcacgc ctgaaccggc acaataaaat cctgttactg gagacacgaa
    25321 tggaatgacg aggcagcctg tcagtcacag gggggctgtt ggcataaaat caacggaaag
    25381 gccaccaaca ccggaattaa gctccacagt ccccgcactg gcaatccatt cccgggaacg
    25441 gcatcaccgc aaactgcgcc agaggcaacc attacaacct ctgtaacgga ttatcagccc
    25501 tggcatcttc cgacagcac
//
LOCUS       DAZUDJ010000069        25282 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.069, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000069 DAZUDJ010000000
VERSION     DAZUDJ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25282
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.069"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1137
                     /locus_tag="ACHY1N_003818"
     CDS             <1..1137
                     /locus_tag="ACHY1N_003818"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004351 - glutamate decarboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006540 - glutamate decarboxylation to
                     succinate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HFS4046035.1"
                     /translation="EYPQSAAIDLRCVNMVADLWHAPAPKNGQAVGTNTIGSSEACML
                     GGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQICWHKFARYWDVELREIPMRPGQLFMD
                     PKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADTGIDIDMHIDAASGG
                     FLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDEEALPQELVFNVDYL
                     GGQIGTFAINFSRPAGQVIAQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKLGPYE
                     FICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRLRGWQVPAFTLGGEATDIVVMR
                     IMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT"
     gene            1293..2828
                     /gene="gadC"
                     /locus_tag="ACHY1N_003819"
     CDS             1293..2828
                     /gene="gadC"
                     /locus_tag="ACHY1N_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance gamma-aminobutyrate antiporter
                     GadC"
                     /protein_id="HFS4046036.1"
                     /translation="MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVF
                     FLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIG
                     FIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGF
                     FAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVFVAFILSYMGVE
                     ASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFT
                     VLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNK
                     NGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVL
                     VLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLV
                     VSFLVVLALPFILYAVHDRKGKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMND
                     KKH"
     gene            2959..4278
                     /locus_tag="ACHY1N_003820"
     CDS             2959..4278
                     /locus_tag="ACHY1N_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 10 glycosylhydrolase"
                     /protein_id="HFS4046037.1"
                     /translation="MDICSRNKKLTIRRPAILVALALLLCSCKSTPPESMVTPPAGSK
                     PPATTQQSSQPMRGIWLATVSRLDWPPVSSVNISTPTSRARVQQQAMIDKLDHLQRLG
                     INTVFFQVKPDGTALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWF
                     NPYRVSVNTKPGTIRELNSTLSQQPASVYVQHRDWIRTSGDRFVLDPGIPEVQDWITS
                     IVAEVVSRYPVDGVQFDDYFYTESPGSLLNDNETYRKYGGAFASKADWRRNNTQQLIA
                     KVSHTIKSIKPGVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRWVEQGLLD
                     YIAPQIYWPFSRSAARYDVLAKWWADVVKPTRTRLYIGIAFYKVGEPSKIEPDWMING
                     GVPELKKQLDLNDAVPEISGTILFREDYLNKPQTQQAVSYLQSRWGS"
     gene            4655..6037
                     /gene="dosC"
                     /locus_tag="ACHY1N_003821"
     CDS             4655..6037
                     /gene="dosC"
                     /locus_tag="ACHY1N_003821"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DosC"
                     /protein_id="HFS4046038.1"
                     /translation="MEMYFKRMKDEWTGLVEQADPLIRAKAAEIALAHAHYLSIEFYR
                     IVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIG
                     IPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDS
                     SASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKILLDSDLGSSLPLSQADFG
                     LWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTV
                     SQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDV
                     DKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLR
                     TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGR
                     NRVELWKASL"
     gene            6062..8461
                     /gene="dosP"
                     /locus_tag="ACHY1N_003822"
                     /gene_synonym="pdeO"
     CDS             6062..8461
                     /gene="dosP"
                     /locus_tag="ACHY1N_003822"
                     /gene_synonym="pdeO"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416006.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-sensing cyclic-di-GMP phosphodiesterase
                     DosP"
                     /protein_id="HFS4046039.1"
                     /translation="MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKL
                     WGYKREEVIGNNIDMLIPRDLRPAHPEYIRHNREGGKARVEGMSRELQLEKKDGSKIW
                     TRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
                     CNRAFTEMFGYCISEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRT
                     GEKIWIKASISPVYDVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGE
                     IICRNIESVLNESHVSLFALRNGMPIHWASSSHGAEVQNAQSWSATIRQRDGAPAGIL
                     QIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
                     YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRI
                     EGTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDVGKNRDYL
                     LSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIF
                     AETGELYGIEALARWHDPQHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRS
                     QNIHIPALSVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFK
                     RIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAI
                     TSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLK
                     I"
     gene            8719..9300
                     /gene="ddpX"
                     /locus_tag="ACHY1N_003823"
     CDS             8719..9300
                     /gene="ddpX"
                     /locus_tag="ACHY1N_003823"
                     /EC_number="3.4.13.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine dipeptidase"
                     /protein_id="HFS4046040.1"
                     /translation="MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHK
                     DAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLWQACPDPQYVVDVTVGSNHSRGT
                     AIDLTLRDEHGNILDMGAGFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGIS
                     SEWWHFELPQAASYPLLADQFTCFISPGTQHVS"
     gene            9314..10864
                     /locus_tag="ACHY1N_003824"
     CDS             9314..10864
                     /locus_tag="ACHY1N_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4046041.1"
                     /translation="MKRSIPFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLD
                     PAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVESDLASSWKASDDQKEWTFTLKDN
                     AKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
                     YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYP
                     GNKPNFKRVSVKIIGESASRRLQLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLR
                     VTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMRGPIPEGMWGYDATA
                     MQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKL
                     ANATMRDRVGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKL
                     LRNALATTDQTQRTRDYQQAQKIVIDDAAYVYLFQKNYQLAMNKEVKGFVFNPMLEQV
                     FNINTMSK"
     gene            10866..11888
                     /locus_tag="ACHY1N_003825"
     CDS             10866..11888
                     /locus_tag="ACHY1N_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4046042.1"
                     /translation="MTFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDR
                     ASDAIVENIRQQLGLDQPLYVQFYRYVSDLFHGYLGTSIRTGRPVLEELRIFFPATLE
                     LAFGALLLALLIGIPLGILSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGH
                     LQILPGGGRLDDWLDPPTHVTGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGI
                     VARQIRSAMLEQLSEDYIRTARASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYG
                     AVLTETVFAWPGMGAWVVTSIQALDFPAVMGFAVVVSFAYVLVNLVVDLLYLWIDPRI
                     GRGGGE"
     gene            11885..12781
                     /gene="ddpC"
                     /locus_tag="ACHY1N_003826"
     CDS             11885..12781
                     /gene="ddpC"
                     /locus_tag="ACHY1N_003826"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D,D-dipeptide ABC transporter permease"
                     /protein_id="HFS4046043.1"
                     /translation="MMLSEETSAVRPQKQTRFNGAKLVWMLKGSPLTVTGAVIIVLML
                     LMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLV
                     VVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAM
                     LAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQA
                     SLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAV
                     GFNLFGDGIRDLLDPKAGGKQS"
     gene            12778..13764
                     /locus_tag="ACHY1N_003827"
     CDS             12778..13764
                     /locus_tag="ACHY1N_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4046044.1"
                     /translation="MTQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGES
                     GSGKSVTAMLIMRLLQTGSYCVHRGQISLLGDDVLNAREKQLRQWRGARVAMIFQEPM
                     TALNPTRRIGLQMMDVIRHHQPISRREARAKAIALLEEMQIPDAVEVMSRYPFELSGG
                     MRQRVMIALAFSCEPQLIIADEPTTALDVTLQLQLLRLLKHKARASGTAVLFISHDMV
                     VVSQLCDSVYVMYAGSVIESGVTADIIHHPRHPYTIGLLQCAPEHGVPRQPLPAIPGT
                     VPNLTHLPEGCAFRDRCYAAGAQCENVPALTACGDNNQRCACWYPQQEVISV"
     gene            13757..14683
                     /locus_tag="ACHY1N_003828"
     CDS             13757..14683
                     /locus_tag="ACHY1N_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015440 - ABC-type peptide transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide/dipeptide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4046045.1"
                     /translation="MSDTLLTLRDVHINFPARKNWLGKTTEHVHAINGIDLQIRRGET
                     LGIVGESGCGKSTLAQLLMGMLQPSHGQYIRSGSQRIMQMVFQDPLSSLNPRLPVWRI
                     ITEPLWIAKRSSEQQRRALAEELAVQVGIRPEYLDRLPHAFSGGQRQRIAIARALSSQ
                     PDVIVLDEPTSALDISVQAQILNLLVTLQENHGLTYVLISHNVSVIRHMSDRVAVMYL
                     GQIVELGDAQQVLTAPAHPYTRLLLDSLPAIDKPLEEEWALRKTDLPGNRTLPQGCFF
                     YERCPLATSGCEVRQSLAIREDGRELRCWRAL"
     gene            complement(14739..15170)
                     /gene="osmC"
                     /locus_tag="ACHY1N_003829"
     CDS             complement(14739..15170)
                     /gene="osmC"
                     /locus_tag="ACHY1N_003829"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin OsmC"
                     /protein_id="HFS4046046.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEK
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKS
                     EVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS"
     gene            15516..15731
                     /gene="bdm"
                     /locus_tag="ACHY1N_003830"
     CDS             15516..15731
                     /gene="bdm"
                     /locus_tag="ACHY1N_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310112.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HFS4046047.1"
                     /translation="MFTYYQAENSTAEPALVNAIEQGLRAEHGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
     gene            15833..15970
                     /gene="sra"
                     /locus_tag="ACHY1N_003831"
     CDS             15833..15970
                     /gene="sra"
                     /locus_tag="ACHY1N_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HFS4046048.1"
                     /translation="MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAE
                     K"
     gene            16127..17824
                     /gene="maeA"
                     /locus_tag="ACHY1N_003832"
     CDS             16127..17824
                     /gene="maeA"
                     /locus_tag="ACHY1N_003832"
                     /EC_number="1.1.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HFS4046049.1"
                     /translation="MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLG
                     LLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPV
                     IYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRI
                     TDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAA
                     VTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFM
                     VDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRMEATPQDIIAWTEGNALVATGSPFNPVV
                     WKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLV
                     LPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI"
     gene            17958..18968
                     /gene="adhP"
                     /locus_tag="ACHY1N_003833"
     CDS             17958..18968
                     /gene="adhP"
                     /locus_tag="ACHY1N_003833"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HFS4046050.1"
                     /translation="MKAAVVTKDHHVDVTDKTLRSLKHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETL
                     CRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIR
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSRTEDA
                     AKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDG
                     IEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDF
                     RR"
     gene            19115..19399
                     /locus_tag="ACHY1N_003834"
     CDS             19115..19399
                     /locus_tag="ACHY1N_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415994.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antitoxin"
                     /protein_id="HFS4046051.1"
                     /translation="MKMANHPRPGDIIQESLDELNVSLREFARAMEIAPSTASRLLTG
                     KAALTPEMAIKLSVVIGSSPQMWLNLQNAWSLAEAEKTVDVSRLRRLVTQ"
     gene            complement(19450..20103)
                     /gene="fdnI"
                     /locus_tag="ACHY1N_003835"
     CDS             complement(19450..20103)
                     /gene="fdnI"
                     /locus_tag="ACHY1N_003835"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit gamma"
                     /protein_id="HFS4046052.1"
                     /translation="MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLT
                     QTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIIEVLKGNEHK
                     VADVGKYNAGQKMMFWSIMSMIFVLLVTGVIILRPYFAQYFPMQVVRYSLLIHAAAGI
                     ILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKNHPRWYREIEKAEAKKESEEGI"
     gene            complement(20096..20980)
                     /gene="fdnH"
                     /locus_tag="ACHY1N_003836"
     CDS             complement(20096..20980)
                     /gene="fdnH"
                     /locus_tag="ACHY1N_003836"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase N subunit beta"
                     /protein_id="HFS4046053.1"
                     /translation="MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKA
                     CQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMH
                     CEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKC
                     TLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEG
                     VGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHY
                     IGIGPNKEVDDDEEDHHE"
     gene            complement(20993..24040)
                     /gene="fdnG"
                     /locus_tag="ACHY1N_003837"
     CDS             complement(20993..24040)
                     /gene="fdnG"
                     /locus_tag="ACHY1N_003837"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_function: GO:0047111 - formate dehydrogenase
                     (cytochrome-c-553) activity [Evidence IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(23453..23455),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HFS4046054.1"
                     /translation="MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAK
                     EIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYV
                     NSENRLRYPEYRAPGSDKWQRISWEEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLS
                     TGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIR
                     SGTDITFLSGVLRYLIENNKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYD
                     KSSWNYQFDENGYAKRDETLTHPRCVWNLLKEHVSRYTPDVVENICGTPKADFLKVCE
                     VLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLAGQVNYWSNYPKFFVSL
                     MKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDK
                     NKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDG
                     SIANSGRWLLWHWKGQDAPGEARNDGEILAGIYHHLRELYQAEGGKGVEPLMKMSWNY
                     KQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYT
                     GSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLI
                     QWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETP
                     LGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIA
                     QPEQFVEISETLAAAKGINNGDRVTVSSKRGFIRAVAVVTRRLKLLNVNGQQVETVGI
                     PIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA"
     gene            24272..25153
                     /gene="yddG"
                     /locus_tag="ACHY1N_003838"
     CDS             24272..25153
                     /gene="yddG"
                     /locus_tag="ACHY1N_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415990.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid efflux DMT transporter YddG"
                     /protein_id="HFS4046055.1"
                     /translation="MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLS
                     GLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLW
                     PSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYF
                     LAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMVFSTPVMIK
                     LISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGA
                     LMVCGGSLLCWLATRRG"
BASE COUNT         6162 a         6449 c         6413 g         6258 t
ORIGIN      
        1 gaatatccgc aatccgcagc catcgacctg cgttgcgtaa atatggttgc cgatctgtgg
       61 catgcgcctg cgccgaaaaa tggtcaggcc gttggcacca acaccattgg ttcttccgag
      121 gcctgtatgc tcggcgggat ggcgatgaaa tggcgttggc gcaagcgtat ggaagctgca
      181 ggcaaaccaa cggataaacc aaacctggtg tgcggtccgg tacaaatctg ctggcataaa
      241 ttcgcccgct actgggatgt ggagctgcgt gagatcccta tgcgccccgg tcagttgttt
      301 atggacccga aacgcatgat tgaagcctgt gacgaaaaca ccatcggcgt ggtgccgact
      361 ttcggcgtga cctacactgg taactatgag ttcccacaac cgctgcacga tgcgctggat
      421 aaattccagg ccgataccgg tatcgacatc gacatgcaca tcgacgctgc cagcggtggc
      481 ttcctggcac cgttcgtcgc cccggatatc gtctgggact tccgcctgcc gcgtgtgaaa
      541 tcgatcagtg cttcaggcca taaattcggt ctggctccgc tgggctgcgg ctgggttatc
      601 tggcgtgacg aagaagcgct gccgcaggaa ctggtgttca acgttgacta cctgggtggt
      661 caaattggta ctttcgccat caacttctcc cgcccggcgg gtcaggtaat tgcacagtac
      721 tatgaattcc tgcgcctcgg tcgtgaaggc tacaccaaag tacagaacgc ctcttaccag
      781 gttgccgctt atctggcgga tgaaatcgcc aaactggggc cgtatgagtt catctgtacg
      841 ggtcgcccgg acgaaggcat cccggcggtt tgcttcaaac tgaaagatgg tgaagatccg
      901 ggatacaccc tgtacgacct ctctgaacgt ctgcgtctgc gcggttggca ggttccggcc
      961 ttcactctcg gcggtgaagc caccgacatc gtggtgatgc gcattatgtg tcgtcgcggc
     1021 ttcgaaatgg actttgctga actgttgctg gaagactaca aagcctccct gaaatatctc
     1081 agcgatcacc cgaaactgca gggtattgcc cagcagaaca gctttaaaca tacctgataa
     1141 cgtttaacgg taacggtgtc ccgaaacgaa cccgtttcgg gacaatttcc aaagtctgtt
     1201 cactggcatt agcaacggaa aatattgttc tgaatacgct tcagaacaaa acaggtgcgg
     1261 ttccgacagg aataccgttt tagggggata atatggctac atcagtacag acaggtaaag
     1321 ctaagcagct cacattactc ggattctttg ccataacggc atcgatggta atggctgttt
     1381 atgaataccc taccttcgca acatcgggct tttcattagt cttcttcctg ctattaggcg
     1441 ggattttatg gtttattccc gtgggacttt gtgctgcgga aatggccacc gtcgacggct
     1501 gggaagaagg tggtgtcttc gcctgggtat caaatactct ggggccgaga tggggatttg
     1561 cagcgatctc atttggctat ctgcaaatcg ccattggttt tattccgatg ctctatttcg
     1621 tgttaggggc actctcctac atcctgaaat ggccagcgct gaatgaagac cccattacca
     1681 aaactattgc agcactcatc attctttggg cgctggcatt aacgcagttt ggtggcacga
     1741 aatacacggc gcgaattgct aaagttggct tcttcgccgg tatcctgtta cctgcattta
     1801 ttttgatcgc attagcggct atttatctgc actccggtgc ccccgttgct atcgaaatgg
     1861 attcgaagac cttcttccct gacttctcta aagtgggcac actggttgta tttgttgcct
     1921 tcattttgag ttatatgggc gtagaagctt ccgcaactca cgtcaatgaa atgagcaacc
     1981 ccgggcgcga ctatccactg gctatgttac tgctgatggt ggcggcaatc tgcttaagct
     2041 ctgttggcgg tttatctatt gcgatggtca ttccgggtaa tgaaatcaac ctctccgcag
     2101 gtgtaatgca aacctttacc gttctgatgt cccatgtggc accggaaatt gagtggacgg
     2161 ttcgcgtgat ctccgcactg ctgttgctgg gtgttctggc ggaaatcgcc tcctggattg
     2221 ttggtccttc tcgcgggatg tatgtcacag cgcagaaaaa cctgctgcca gcggcattcg
     2281 ctaaaatgaa caaaaatggc gtaccggtaa cgctggtcat ttcgcagctg gtgattactt
     2341 ctatcgcgtt gatcatcctc accaataccg gtggcggtaa caacatgtcc ttcctgatcg
     2401 cactggcgct gacggtggtg atttatctgt gtgcttattt catgctgttt attggctaca
     2461 tagtgttggt tcttaaacat cctgacttaa aacgcacatt taatatccct ggtggtaaag
     2521 gggtgaaatt ggtcgtggca attgtcggtc tgctgacttc aattatggcg tttattgttt
     2581 ccttcctgcc gccggataac atccagggtg attctaccga tatgtatgtt gaattactgg
     2641 ttgttagttt cctggtggta cttgccctgc cctttattct ctatgctgtt catgatcgta
     2701 aaggcaaagc gaataccggc gtcactctgg agccaatcaa cagtcagaac gcaccaaaag
     2761 gtcacttctt cctgcacccg cgtgcacgtt caccacacta tattgtgatg aatgacaaga
     2821 aacactaacc atgtctgaat ggttataaga caagggagcg ataagtcatc gctccctttt
     2881 tcgtgcttgc tgtcgtattg acttaaccgg gataagtacg agaatgagcg cacatctgtt
     2941 taccggaaac cagcacatat ggatatctgc tcccgaaaca agaaattaac gattagaaga
     3001 ccagcgatac tagttgcact ggcactttta ctgtgtagtt gtaaaagcac gcctccagag
     3061 tccatggtga caccaccagc aggttcaaag ccaccagcca cgacgcaaca atcgtcacaa
     3121 ccgatgcgtg gcatctggct ggccacggtt tctcggctcg actggccacc ggtttcctcg
     3181 gttaacatta gtacccccac cagccgggcc cgtgtacaac aacaggcgat gatcgacaaa
     3241 ctggatcatc tgcaacgtct cggcataaac acggtctttt tccaggtcaa gccggacggt
     3301 accgccctgt ggccatcgaa aattttgccg tggtccgatc ttatgaccgg taagattggt
     3361 gaaaatccgg gttacgatcc gctgcaattt atgctcgacg aagcccacaa gcgtgggatg
     3421 aaagtacacg cctggtttaa cccctatcgc gtatcggtta atacgaagcc cggtactatc
     3481 agggaactga atagcactct gtctcaacaa ccggcgagcg tctatgtgca acaccgcgac
     3541 tggatcagaa cgtctggcga tcgctttgtc ctcgacccgg gcatccctga ggttcaggac
     3601 tggatcacat caatagtcgc cgaagtggtt tcccgctatc cggtagatgg cgtgcagttt
     3661 gacgactatt tctatacgga gtcaccgggt tcactgctaa atgataacga aacgtaccgt
     3721 aaatacggag gcgcatttgc gtcaaaagca gactggcggc gcaacaatac tcagcagtta
     3781 attgcaaagg tatcgcacac cattaaaagc attaagccgg gagtcgaatt tggtgttagc
     3841 ccggcaggcg tgtggcgtaa ccgatcacac gatccgctcg gttccgatac ccgaggcgcg
     3901 gcagcctatg acgaatccta cgctgacacc cgtcgatggg tggaacaagg attgctggat
     3961 tacattgctc cccaaattta ctggccgttc tcacggagtg ccgcgcgtta tgacgtgttg
     4021 gcaaaatggt gggcggatgt cgttaaaccg accaggaccc gcctgtatat cggtatcgcc
     4081 ttctataaag tgggtgaacc ttcaaagata gagccagact ggatgattaa cggcggcgta
     4141 ccggaactga aaaagcagct cgatcttaac gatgcggtac cagaaattag cggcaccatc
     4201 ttgttccgtg aggactatct gaataaaccg cagactcaac aagcggtcag ctatctgcaa
     4261 agtcgttggg gcagttaaac tcccatgctt actttgtaac aagccggtgc tttacccacc
     4321 ggcgtgttac accttgtgaa atatcccact agtaatcatg cttacataag tcaaattaac
     4381 cacgcaatta accacactta gttaaacagc tataaatccc taataaaaat gtatgaatat
     4441 gaaaaaccat acgatattcg ctgtcaccga aaaataatta cgatgggcta tactcttctg
     4501 aagaacagta gcgtagattg aaactgtcct aagtcgctta tttcttttca gtatatcttc
     4561 atatttcagg agaatatggt gcagttagtc gatctcgcac gttgcgtttc gttttgattc
     4621 cgtctgattt cccagcctta taagggtgtg aattatggag atgtatttta aaagaatgaa
     4681 agatgagtgg accggacttg tcgaacaggc agatcctctc attcgtgcta aagccgcaga
     4741 aattgccctt gcgcatgctc attatctgag tatcgagttt tatcgaattg tccgcatcga
     4801 cccgcatgcc gaagaattct tgagtaatga acaagttgag cggcagttga aaagtgcgat
     4861 ggaacgctgg attattaacg tgctttctgc ccaggttgac gatgtcgaaa ggctaataca
     4921 aatccagcat accgtcgcgg aagtgcatgc ccgcatagga attccggtag aaattgtcga
     4981 gatggggttt cgggtgctga aaaaaatcct ctatccggta atcttctctt cggattattc
     5041 tgccgcagaa aaacttcagg tctaccattt ctcgattaac agtattgata tcgctatgga
     5101 agtgatgacc cgcgcgttta cctttagtga cagtagtgcc tcaaaggaag atgaaaacta
     5161 tcgtatcttc tcgttactgg aaaacgccga agaagaaaaa gaacggcaaa tagcctcaat
     5221 actttcatgg gaaatagata ttatctataa aatcctgctg gattctgatt taggcagtag
     5281 tttgccttta agccaggctg attttggcct gtggtttaac cataaaggtc gacattattt
     5341 tagcggcatt gccgaagtag gccatatctc ccgtctgatt caggatttcg acggtatttt
     5401 caatcaaacc atgcgtaaca ccaggaattt gaataacaga agtttgcggg tgaagtttct
     5461 attacagata agaaataccg tatcgcaaat tattaccttg ctgcgtgaat tgtttgaaga
     5521 agtatcgcgc cacgaagtcg gtatggatgt actgacgaaa ttacttaacc gccgtttcct
     5581 gccgactatc ttcaaacgcg aaattgccca tgccaaccgg accggtacac cgctgtcagt
     5641 gctgattatt gacgttgata aattcaaaga gatcaacgat acgtggggcc ataacactgg
     5701 cgatgaaatt ctgcgtaaag tctctcaggc cttttatgac aacgtccgca gtagtgatta
     5761 tgttttccgc tacgggggcg atgaatttat cattgttttg actgaagctt ctgaaaacga
     5821 aacgttacgt accgcagaac gtattcgcag tcgggtggag aaaaccaaac tgaaagccgc
     5881 aaacggcgag gatattgccc tctcactttc catcggtgcc gccatgttta atggtcatcc
     5941 tgactatgag cgcctcattc aaatagccga tgaagctctg tatatcgcca aaagacgagg
     6001 tagaaaccgt gttgaactct ggaaagccag tctttagatg cgccaggatg cagaggtaat
     6061 catgaagcta accgatgcgg ataatgccgc cgatggcatt tttttccccg cccttgagca
     6121 aaatatgatg ggtgcggtgt taattaacga aaatgatgaa gtgatgtttt tcaaccccgc
     6181 cgcagagaag ctctgggggt acaaacgtga agaagtcatt ggcaataaca ttgatatgct
     6241 gattccgcgg gatttgcgtc ctgcgcatcc tgaatacatt cgtcataacc gtgaaggcgg
     6301 taaagcgcgt gtcgagggga tgagtcggga gctgcagctg gagaaaaaag acggcagtaa
     6361 aatctggacc cgttttgcgc tatcgaaagt gagcgccgag gggaaagttt attacctggc
     6421 gctggtacgg gatgccagcg tagaaatggc gcaaaaagaa cagactcgac aattgattat
     6481 tgccgttgac catctcgacc gaccggtgat tgtcctcgat ccggaacgcc atattgtgca
     6541 gtgcaatcgc gcatttaccg aaatgtttgg ttactgcatt agcgaagcca gcggtatgca
     6601 gcccgataca ctcctgaaca ttcctgaatt ccctgccgat aaccgcattc gtttacaaca
     6661 gttgctatgg aaaaccgccc gcgatcagga tgaatttctg ctgttgacgc gcaccggtga
     6721 aaaaatctgg attaaagcct ctatcagccc ggtttatgac gtgctcgcgc atctgcagaa
     6781 cctggtaatg accttctcgg atatcaccga agaacggcaa atccgccagc ttgaaggcaa
     6841 tattctcgcc gccatgtgca gcagcccgcc atttcatgaa atgggggaaa tcatttgtcg
     6901 taacatcgaa tctgttctca acgaatcgca tgtttcgctg ttcgcactgc gcaacgggat
     6961 gccgatacac tgggcgtcat cttcgcacgg tgcagaagtt caaaatgcgc aaagctggtc
     7021 agcgaccatt cgtcagcgtg atggcgcgcc tgcggggatc ctgcaaatta aaacctcgtc
     7081 aggagcagaa accagcgcct ttatcgaacg cgtggcagat atcagtcagc atatggccgc
     7141 gctggcgctg gaacaggaaa aaagccgcca gcatattgaa caactcatcc aatttgatcc
     7201 gatgaccggt ctgccaaatc gcaataacct gcacaattac ctcgatgacc tggtcgacaa
     7261 agccgtctct ccggtggtgt atctcatcgg tgttgaccat attcaggatg tgattgatag
     7321 ccttggctat gcgtgggccg atcaggcatt gctggaagtg gtcaatcgct ttcgtgaaaa
     7381 actcaaaccg gatcagtatc tctgtcgtat cgaaggtacg cagtttgtcc tcgtgagcct
     7441 ggaaaacgac gtcagtaaca ttacccaaat cgccgatgag ctacggaatg tggtcagcaa
     7501 gccgataatg attgacgata aacccttccc gcttaccttg agtattggca tcagctacga
     7561 cgtgggtaaa aaccgcgatt acctgctctc cactgctcac aatgcaatgg attatattcg
     7621 caagaatggc ggtaacggct ggcagttctt cagcccggcg atgaacgaaa tggtaaaaga
     7681 gcgtttggtt ttaggcgcag cgctgaaaga agcgattagc aataaccaac tgaaacttgt
     7741 ttaccagccg caaatcttcg cagaaacggg tgaactgtac ggcatcgaag cccttgcgcg
     7801 ctggcacgat ccccagcatg gtcatgtgcc cccttcacgg tttattcctc tcgcagaaga
     7861 gattggtgaa atcgaaaata ttgggcgctg ggtcatcgcg gaagcttgcc gtcagttagc
     7921 agaatggcgt agccagaata ttcatatccc ggcgctttcc gttaacttgt cggcactgca
     7981 ctttcgcagt aatcaactgc ctaatcaggt gtctgatgca atgcacgcct ggggtattga
     8041 cggccaccag ctgacggtag aaatcacgga aagcatgatg atggaacacg ataccgaaat
     8101 ctttaagcgc attcagatcc tgcgtgatat gggcgtgggc ttatcggtag atgattttgg
     8161 tacgggcttt tccggattat cccgcttagt cagtcttccg gtaacggaaa tcaaaattga
     8221 caaaagtttt gtcgatcgtt gtctgaccga aaaacgcatc cttgccttac ttgaagccat
     8281 taccagcatt gggcaaagcc tcaatttaac cgtcgtggcg gaaggggtcg aaaccaaaga
     8341 gcaatttgag atgctacgca agatccactg tcgcgttatt cagggatatt tcttttcccg
     8401 ccccctaccc gccgaagaaa ttccaggctg gatgagcagc gtgttaccgc tgaaaatctg
     8461 acaaattcct ctcgcccgca ctcgcgggtt ttcatttaac gtgacactgt cacttaaata
     8521 ctgtgatttc agctacgatt ccgggagatt ccttccttaa cttcccctct tgcaccaaaa
     8581 ctgcactacg ctgcacaaat gttgatcaaa agttaaaaaa tataacttta agccagcatt
     8641 ctggcgctta tcccggcatg gcatgagatc tgcataagcg gaaagcgcag caatttttgt
     8701 cttatacagg aaccgtttat gtcggatacc accgaactgg ttgatttagc cgtaatcttc
     8761 cctgatctgg agatcgaatt gaaatacgcc tgcgctgata acatcacagg taaagctatt
     8821 tatcagcaag cgcgttgtct gctacacaag gatgcgatta ccgcgctggc gaaaagtatc
     8881 agtatcgccc agctgtcagg cttacaactg gtgatttacg atgcgtatcg cccacaacaa
     8941 gcacaggcga tgttgtggca agcctgccca gacccgcaat atgttgttga tgtgacggtc
     9001 ggttctaatc acagccgtgg cacggcgatc gacctgacgc ttcgtgatga gcacgggaac
     9061 atcctcgata tgggcgcagg gttcgatgaa atgcacgagc gctcccatgc ctatcaccct
     9121 tccgtcccgc ccgccgctca gcgcaatcgg ctgttgctga atgcgataat gactggtggc
     9181 ggttttgtcg gtatctccag cgaatggtgg cacttcgaat taccccaggc agcgagttac
     9241 cctctgctcg ctgatcaatt cacctgtttt atatcccctg gcacacaaca cgtcagttaa
     9301 tcaggaaact gtcatgaaga gatcgatacc gtttcgtccc acattgctcg cgctcgtcct
     9361 tgccacaaat ttcccggttg cgcacgccgc cgtaccgaaa gatatgctgg tgattggtaa
     9421 ggccgccgat ccacaaaccc tcgacccggc ggtaacaata gataataacg actggacggt
     9481 gacctacccg tcttatcagc ggctggttca gtacaaaacg gacggtgata aaggctcaac
     9541 cgacgttgaa agcgatctgg caagtagctg gaaagcgtct gacgatcaaa aagagtggac
     9601 gttcaccctg aaggacaatg ctaaatttgc cgatggcaca ccggtcactg ccgaagcagt
     9661 aaaactctct tttgagcggc tactaaaaat cggccaaggg ccagcagaag catttcccaa
     9721 agatttaaag attgatgctc ccgacgaaca tacggtgaag tttaccctta gccagccatt
     9781 cgcaccgttc ctctacacgc tggcgaatga cggtgcatcc attatcaatc cggcggtctt
     9841 aaaggaacat gcagcggatg atgctcgcgg cttcctcgcg caaaataccg ccggttccgg
     9901 accatttatg ctgaaaagct ggcaaaaagg tcagcaatta gttctggtgc caaatccgca
     9961 ttaccccggc aataaaccga actttaagcg agtatcggta aaaattatcg gtgaaagtgc
    10021 ctcccgtcgc ctgcagctct cccgtggcga cattgacatt gccgatgcgc tgccggtgga
    10081 tcaactcaac gccctgaagc aggaaaataa agtcaatgtg gcagagtatc cgtcactgcg
    10141 cgttacctat ctgtatctga ataacagcaa agcgcctctt aatcaggcgg atctgcgtcg
    10201 ggccatttcc tggtctaccg attatcaggg catggttaac ggcattctga gtggtaacgg
    10261 aaaacagatg cgcggcccga ttccggaagg catgtggggc tacgatgcga cggcaatgca
    10321 atacaaccat gacgaaacga aagccaaagc cgaatgggat aaagtgacga gcaaacccac
    10381 cagcctgacg tttctctact ccgataacga tccgaactgg gagcctattg ctttggcgac
    10441 acaatccagt ctcaacaagc tgggcatcaa tgtgaagctg gaaaagctgg cgaacgccac
    10501 catgcgcgac agagtgggta aaggtgatta cgacattgcg attggcaact ggagtccgga
    10561 ttttgccgac ccgtatatgt ttatgaatta ctggtttgag tcagacaaaa aaggtctgcc
    10621 gggtaaccgc tcgttctatg aaaacagtga ggtcgataag ttactgcgca atgcgcttgc
    10681 gaccaccgac cagacgcagc gtacccggga ctaccagcag gcacagaaaa tcgtcattga
    10741 tgacgctgct tatgtgtacc tgttccagaa aaactaccaa ctggcgatga acaaagaggt
    10801 gaaaggcttt gtgttcaatc ccatgctgga acaggtcttc aatatcaata ccatgagtaa
    10861 ataacgtgac cttctggagt attttacgcc aacgctgctg ggggctggtg ctcgtggtgg
    10921 cgggcgtctg cgtgattacg tttattatct cgcatctgat ccctggcgat ccggcgcggt
    10981 tactggcggg tgaccgcgcc agcgatgcta tcgtggaaaa tattcgccag caactgggac
    11041 tggaccagcc actgtatgta cagttttacc gctacgtcag cgacctgttt catggttacc
    11101 tgggaacatc cattcgtacc gggcgtccgg tgctggaaga gttgcgtata tttttcccgg
    11161 cgacgctgga gctggctttt ggtgccctgc tgctggcact cctgattggc atcccgctgg
    11221 gcatactctc tgcagtctgg cgaaatcgct ggctggatca tctggtgcga ataatggcca
    11281 ttaccggaat ctccacacct gcgttctggc ttgggctggg cgtcattgtg ctgttttatg
    11341 gtcatctgca aattcttccc ggcggcggaa ggcttgatga ctggctggat ccaccaacgc
    11401 acgttaccgg cttttatctg ctcgatgcgc tgcttgaagg caacggtgaa gtcttcttca
    11461 atgcgttgca acatctcatc ttaccggcat taacgctggc gttcgttcac ctgggaattg
    11521 tcgctcgcca gatccgctca gcgatgctgg aacaattgag tgaagactac attcgtaccg
    11581 cccgggccag cggcttgccc ggctggtata tcgttttatg ttatgcgcta cccaatgcgt
    11641 tgatcccatc gattaccgta ttgggtttgg cgctgggcga tttgttgtat ggcgcagtgc
    11701 tcaccgaaac cgtttttgcc tggcccggaa tgggtgcatg ggtagtaaca tcaatacagg
    11761 cgctcgactt cccggcagtg atgggctttg ccgtcgtggt ttcatttgct tatgtgctgg
    11821 tcaacctggt ggtggatttg ctctatttgt ggattgatcc gcgtatcgga cgtggaggtg
    11881 gtgaatgatg ctaagcgagg aaacgtccgc cgtacgccca caaaaacaaa cgcgatttaa
    11941 cggtgcaaaa ctggtatgga tgctgaaagg cagtccgctc accgtgaccg gcgcagtcat
    12001 cattgtatta atgctattga tgatgatttt ttcaccgtgg ctggcgacgc atgatcccaa
    12061 cgccattgat ttaaccgccc gccttttgcc gccttctgcg gcgcactggt ttggcaccga
    12121 tgaagtggga cgcgatctgt tcagccgcgt actggtcggc agtcagcaat caattctcgc
    12181 cggattagtc gtggttgcca ttgcgggtat gattggttcg ctactcggat gtctatccgg
    12241 tgtgcttggc ggacgcgcag acgccatcat catgcgcatc atggacatta tgctgtcgat
    12301 tccttcgttg gtactgacaa tggcactggc tgccgctctc gggccgagtt tatttaacgc
    12361 catgctggcg attgctattg tgcgaattcc cttttatgtg cgcctggcgc gggggcaagc
    12421 attagttgta cgccagtata cctatgttca ggcggcgaaa acctttggtg cgtcgcgttg
    12481 gcatctgatc agctggcata ttttacgtaa ctccctgccg ccgctgatcg tgcaggcatc
    12541 gctggatatc ggtagcgcga ttttaatggc cgccacgttg ggatttattg gcctgggtgc
    12601 tcaacaaccg agtgctgaat ggggcgcgat ggtagcgaat ggtcgcaact atgtactcga
    12661 tcagtggtgg tattgcgcat ttccgggggc agcgattttg cttaccgccg ttgggtttaa
    12721 tctctttggt gatggtattc gcgatctgct tgacccgaaa gcaggaggaa agcagtcatg
    12781 acccaacccg ttctggacat tcaacagctg catttgagtt tccccggttt taacggtgat
    12841 gttcacgcgc tcaacaatgt gtccttgcag attaaccgcg gcgaaattgt cggtctggtg
    12901 ggagaatccg gctcaggtaa atcagtcacc gcaatgctga ttatgcgtct gctacagacg
    12961 ggcagttatt gcgtacatcg ggggcagatt tcactgctgg gagacgatgt tcttaacgct
    13021 cgggaaaaac agcttcgtca gtggcgcggc gcacgagtgg cgatgatctt tcaggaaccg
    13081 atgaccgccc tcaatccgac acgtcgaata ggtcttcaga tgatggacgt gatccgccat
    13141 catcaaccaa taagtcgtcg ggaagccaga gctaaagcga ttgccctgct ggaagagatg
    13201 caaatcccgg atgccgtgga agttatgtcg cgctatccgt ttgagctttc aggtggtatg
    13261 cgccagcggg taatgattgc gctggcattc tcctgcgagc cgcaattgat tattgccgac
    13321 gaaccgacta cggcgctgga cgtcacgcta cagttgcagc tactgcgttt gcttaaacat
    13381 aaagcccgcg ccagtggaac tgcggtactg ttcatcagcc atgatatggt cgtggtgtcg
    13441 caactgtgcg atagcgttta cgtgatgtat gccggaagcg taattgaaag cggcgtgacg
    13501 gcagacatta tccatcatcc ccggcatccg tataccattg gtttgctgca atgcgcacca
    13561 gaacatggag taccacgcca gccattaccc gccattccag ggacggtacc aaacctcacc
    13621 catttgcctg aaggctgcgc ttttcgcgat cgttgctatg cggcaggtgc acagtgtgaa
    13681 aacgtcccgg cgctgacagc gtgtggtgac aacaaccagc gctgcgcctg ttggtatccg
    13741 cagcaggagg tcataagtgt ctgacacgtt attaacgtta cgcgacgtcc atatcaattt
    13801 cccggcccgt aaaaactggc ttggtaaaac tacggaacat gttcatgcca ttaatggtat
    13861 tgatttacag atccgccgtg gtgaaacctt agggatcgtc ggcgagtcag gctgcggcaa
    13921 aagcaccctc gcacagcttt taatgggcat gctgcaaccg agccacgggc agtacatccg
    13981 ttcaggctca caacgcatta tgcagatggt gtttcaggac ccgctctctt cgcttaatcc
    14041 gcgcttaccg gtgtggcgca tcatcacaga accgctctgg atagctaagc gtagtagtga
    14101 acaacagcgg cgagcgttgg cagaggagct ggctgtgcag gtgggtattc gtccggagta
    14161 tctcgaccgc ctgcctcatg cgttctccgg cgggcagcgg caacgtatcg ccattgccag
    14221 agcactctct tcgcagcctg acgtgattgt gcttgatgag ccaacctctg cgctggatat
    14281 ctccgtgcag gcgcagatcc tcaatttact ggtaacgcta caggaaaatc acgggctgac
    14341 ctatgtgctg atttcacaca atgtctcggt gatacgtcat atgagcgatc gggtggcggt
    14401 gatgtatctc gggcagattg tagaactggg cgacgcgcaa caggtgctaa cggctccggc
    14461 acatccatac acccgattat tgctggattc cctccccgcc attgataaac cgctggagga
    14521 agaatgggca ttacgtaaaa cggatctgcc gggaaaccgc acgttgccgc aaggctgttt
    14581 tttctacgaa cgttgccccc ttgcaaccag cggatgtgaa gtccggcaat cattagcaat
    14641 aagggaggac ggacgtgagc tccggtgctg gcgggcgctg tagagatgct aacaacgcat
    14701 caggcattca cgcgcctgac gcgtcatccg gcaatgcttt acgatttcaa ctggtaatcc
    14761 agcgtaattt ccgctttcag tacctgagaa accgggcatc ctgcttttgc tttctggatg
    14821 atgccgtcaa aggtagaggc atcaataccc ggcaccgcaa cttcactctt cagtgcgatt
    14881 ttcgtaatcg caaaaccggc atccacttta tccagcgaca catcggcggt ggtatcaatc
    14941 gatgttggcg taaatcccgc ttcccccagc attaatgaaa gcgccattga gaaacatgcg
    15001 gcatgcgctg cgccaatcag ttcttcaggg ttagttcctt tttcgccttc aaaacgcgtg
    15061 ttaaatccat acggctgttg gttcagcaca ccactctcgg tggatactgt tcccttcccg
    15121 cgtttgatat cgccttccca gtgtgcctga cctttcttat ggattgtcat tgttgctctc
    15181 ctgtgggctt aaaaaggaaa ttatagacta cgtgagaaac agcacgagga taagcaggat
    15241 attccgaata aaaatccggc agaaatatta cttctgcact taaattaaat ttccacaata
    15301 gataaccggg aatatataac ccaagagata ttgcattaat attaatcaac tcaccacaat
    15361 aataatacct atcaatatca tgaggttaaa atataaaaat catcaaccag gactaatctt
    15421 aacaacgaag cggcaaatat ttgccatgct gaatgtgctt tataaatctg cgatccgtag
    15481 cagacaccat aaatacacag acacggagaa tcactatgtt tacttattat caggcagaaa
    15541 attcaacagc agaacccgct ctggttaatg ccattgagca aggccttcgg gcagagcacg
    15601 gtgttgtcac tgaagatgac attctcatgg agctgaccaa atgggtggaa gcttctgata
    15661 acgacatcct cagtgatatc taccagcaaa cgatcaatta tgtggtcagt ggccagcacc
    15721 ctacgcttta aggtgctatg cttgatcggc aacctaattt aggggtttag cacgtgtttc
    15781 ttcgctacgg cgatgttgtc cttaaaacta gcaacaggat tgaggagtta aaatgaaatc
    15841 gaaccgtcag gcacgtcata ttcttggact ggaccataaa atttctaacc agcgcaaaat
    15901 agttaccgaa ggtgacaaat ccagcgtggt aaataatcca accggcagaa aacgccccgc
    15961 tgaaaagtaa ttcataacca tcagtcctca atgacgatta aacaccattg cctgcgcaat
    16021 ggtgtttttg tttttatctg ctttatactt ggggccgacg ccctggcggt aaagcaaaga
    16081 cgataaaagc gtgccaggga tggatattca aaaaagagtg agtgacatgg aaccaaaaac
    16141 aaaaaaacag cgttcgcttt atatccctta cgctggccct gtactgctgg aatttccgtt
    16201 gttgaataaa ggcagtgcct tcagcatgga agaacgccgt aacttcaatc tgctggggtt
    16261 actgccggaa gtggtcgaaa ccatcgaaga acaagcggaa cgagcatgga tccagtatca
    16321 gggattcaaa accgaaatcg acaaacacat ctacctgcgt aacatccagg acaccaacga
    16381 aaccctcttc taccgtctgg taaacaatca tcttgatgag atgatgcctg ttatttatac
    16441 cccaaccgtc ggcgcagcct gtgagcgttt ttctgagatc taccgccgtt cacgcggcgt
    16501 gtttatctct taccagaacc gccacaatat ggacgatatt ctgcaaaacg taccaaacca
    16561 taatatcaaa gtgattgtgg tgactgacgg tgaacgtatt ctggggcttg gtgaccaggg
    16621 catcggcggg atgggcattc cgatcggtaa actgtcgctc tataccgcct gtggcggcat
    16681 cagcccggcg tatacccttc cggtggtgct ggatgtcgga acgaacaacc aacagttgct
    16741 taacgatccg ctgtatatgg gctggcgtaa tccgcgtatc actgacgacg aatactatga
    16801 attcgttgat gaatttatcc aggctgtgaa acaacgctgg ccggacgtgc tgttgcagtt
    16861 tgaagacttc gcacaaaaaa atgcgatgcc gttacttaac cgctatcgca atgaaatttg
    16921 ttcctttaac gatgacattc agggcactgc ggcggtaaca gtcggcaccc tgatcgcagc
    16981 aagccgcgcg gcaggtggtc agttaagcga gaaaaaaatc gtcttccttg gcgcaggttc
    17041 agcgggatgc ggcattgccg aaatgatcat cgcccagacc cagcgcgaag gattaagcga
    17101 ggaagcggcg cggcagaaag tctttatggt cgatcgcttt ggcttgctga ccgacaagat
    17161 gccgaacctg ctgcctttcc agaccaaact ggtgcagaag cgcgaaaacc tcagtgactg
    17221 ggataccgac agcgatgtgc tgtcactgct ggatgtggtg cgcaatgtaa aaccagatat
    17281 tctgattggc gtctcaggac agaccgggct gtttacggaa gagatcatcc gtgagatgca
    17341 taaacactgt ccgcgtccga tcgtgatgcc gctgtccaac ccgacgtcac gcatggaagc
    17401 cacaccgcag gacattatcg cctggactga aggtaacgcg ctggtcgcca ctggcagtcc
    17461 gtttaatcca gtggtatgga aagataaaat ctaccctatc gcccagtgta acaacgcctt
    17521 tattttccca ggcatcgggc tgggtgttat tgcttccggc gcgtcacgta tcaccgatga
    17581 gatgctgatg tcggcaagtg aaacgcttgc tcagtattcg ccgctggtcc tgaacggcga
    17641 aggtctggta ctaccggaac tgaaagatat tcagaaagtc tcccgcgcaa ttgcgtttgc
    17701 ggttggcaaa atggcgcagc agcaaggcgt ggcggtgaaa acctctgccg aagccctgca
    17761 acaggccatt gacgataatt tctggcaagc cgaataccgc gactaccgcc gtacctccat
    17821 ctaagcctgc gcccggtagt gaaggctacc gggctatttc cctctccctt tttcagatct
    17881 catccatact gggtagtggc gaataaatct catttgcctc acctgctatg cagaacatca
    17941 tccgaaaagg aggaactatg aaggctgcag ttgttacgaa ggatcatcat gttgacgtta
    18001 cggataaaac actgcgctca ctgaaacatg gcgaagccct gctgaaaatg gagtgttgtg
    18061 gtgtatgtca taccgatctt catgttaaga atggcgattt tggtgacaaa accggcgtaa
    18121 ttctgggcca tgaaggcatc ggtgtggtgg cagaagttgg cccaggtgtc acctcattaa
    18181 aaccaggcga tcgtgccagc gtggcgtggt tctacgaagg atgcggtcat tgcgaatact
    18241 gtaacagtgg taacgaaacg ctctgccgtt cagttaaaaa tgccggatac agcgttgatg
    18301 gcgggatggc ggaagagtgc atcgtggtcg ccgattacgc ggtaaaagtg ccagatggcc
    18361 tggactcggc ggcggccagc agcattacct gtgcgggggt caccacctac aaagccgtta
    18421 aactgtcaaa aattcgtccc ggtcagtgga ttgctatcta cggtcttggc ggtctgggta
    18481 acctcgccct gcaatacgcg aagaatgtct ttaacgcgaa agtgatcgcc attgatgtca
    18541 atgatgagca gttaaaactg gcaaccgaaa tgggtgcaga tttagcgatt aactcacgca
    18601 ccgaagacgc cgccaaaatt gtgcaggaga aaaccggtgg cgctcacgct gcggtggtaa
    18661 cagcagttgc taaagctgcg tttaactcgg cagttgatgc tgtccgtgca ggcggtcgtg
    18721 ttgtggctgt cggtctgccg ccagagtcta tgagcctgga tatcccacgc cttgtgctgg
    18781 atggcattga agtggtcggt tcgctggtcg gcacgcgcca ggatctaacc gaagccttcc
    18841 agtttgccgc cgaaggcaaa gtggtgccga aagtcgccct gcgtccgtta gcggacatca
    18901 acaccatctt taccgagatg gaagaaggca aaatccgtgg ccgtatggtg attgatttcc
    18961 gccgttaaga ggcctttgct gcgagtgcca gtcctggtgt cgcagcatcg cactctctcc
    19021 gacattaaat ggctaaatgg attattgttc cttcctacgc aacaataatg atagtgttcc
    19081 tgatgaagga acactactga gagtaaagac actgatgaaa atggccaatc atccccgccc
    19141 gggggacatt attcaggaat cactggacga acttaatgtc agcctgcgcg agtttgccag
    19201 agcaatggaa attgctccct caacggcaag ccgattgctg accggaaaag cagctttgac
    19261 accagaaatg gcgattaaac tttccgtggt gatcggcagt tcgccgcaaa tgtggctgaa
    19321 tctgcaaaac gcctggagtc tggcagaggc agaaaaaacg gtggatgtgt cgcgactacg
    19381 ccgtctggtt acgcaataaa aaaatggcgc ttcttaaagc gccattttca gcttaaagtt
    19441 caaaagagat tatatccctt cttcactctc ttttttcgct tctgccttct cgatttcacg
    19501 ataccagcgc ggatggtttt tcttcgccca gcgacggctc accttccctt cgatcatccc
    19561 tttaatcgac cctttcaccc agaatgccat atacatatgg atcaggatgg cgtggatcag
    19621 gatgataccc gcagccgcgt ggatcagcag gctgtagcga acaacctgca tcgggaagta
    19681 ctgcgcaaag tacggacgca agataatcac cccggtcacc agcagcacga aaatcatgct
    19741 catgatcgac cagaacatca tcttttgccc ggcgttgtac ttaccgacat ccgccacttt
    19801 atgctcattg cctttcaata cttcgataat gttcaacagc cacggaatat ctttcttatc
    19861 cgggatgttg tgatgcacaa aacgcacaaa cataaacatc agtgcgacga aaatcgcaat
    19921 gccgaaaaac gggtgcaaaa tgcgtcccat ctgcggcgta ccgaaggttt gcgtcagcca
    19981 ttgcagcgtc gggaagaaga acgaaatccc ggacagcgcc accaggaaga agcaaatcac
    20041 cacggtccag tgacaggcgc gatcaataaa tttggtgcgc acaatcattt tcgacttact
    20101 catgatgatc ctcctcgtca tcgtccactt ccttattcgg gccaataccg atgtagtgga
    20161 aaatcaaccc ggcaaaagtg gcaataaagc cagccgctgc cagcggtttc aacgcgcctt
    20221 tccacaggct taccgaggtg tcgatcttcg gatctttcgg cagaccgtga tacagctccg
    20281 gctgatcggc gtgatgcagc acgtacataa cgtgcgtacc accgacccct tccgggttgt
    20341 agacgccagc atgttcgtaa ccacgcgctt tcagtttcgc cacgcgctgt tccgccagct
    20401 ccagcatctc cttcttggtg ccgaagtgga tagccccggt cggacaggtt ttcacacaag
    20461 ccggttcctg gccgacgctg acgcgatcga cgcagagcgt gcatttatat acccggttat
    20521 cctctttgtt gaggcgcgga atattaaacg gacacccggc aatgcagtaa ccacagccga
    20581 tgcagttttc cgactggaaa tcgacaatcc cgttagcgta ctgaatgatt gcaccagcag
    20641 acgggcacgc cttcaggcag ccgggatctt cacagtgcat acagccgtct ttacggatca
    20701 gccactccag cttgccgttc tgttcggttt cgctaaagcg catcaccgtc caggacttgg
    20761 cgctcagatc ggcggggtta tcgtaaaccc cgacgcagtg ccccacttca tcacggatgt
    20821 cgttccactc cgaacacgcc acctgacagg ctttacagcc gatacaggtg gaaacgtcga
    20881 taagttttgc gacttctgct ttgtaatcac gcacctgaga aggcggcgtg atggagttag
    20941 ttgcggacct tttgataatg tcctgcgttt ccatagccat ctgttcgccc ccttacgcct
    21001 tctcgatgtt gactaagaac gctttatatt ccggcgtttg cgagtttgca tcaccgacat
    21061 tcggcgtcag agtgttagcg atataacctt tacgcgcgac accctcaaag ccccagtgga
    21121 ttggaatacc caccgtttca acctgctgac catttacatt cagtagtttc agacgacgcg
    21181 ttaccacagc caccgcgcgg ataaagccac gcttgcttga gacagtgaca cgatcgccat
    21241 tattaatgcc tttcgccgcc gccagcgttt cgctgatttc cacaaactgt tccggctgag
    21301 caattgcgtt gagcaatgcg tgcttggtcc aggtgtggaa gtgctcggtc agacgatagg
    21361 tcgtacccac atacgggaac tgctcttttt tacccatccg cagtgcgtct tgttcataca
    21421 gacgaacaac cgggttagac accacgttcg gatgcagcgg gttagtgccc agcggcgttt
    21481 caatcggctc gtagtgttcc gggaacggac cttccgccat tttgttgatg gcaaacaggc
    21541 gtcccatccc ttccggctgc atgataaacg gcccggttgg cgtacccggt gcggcattgc
    21601 cgaagtcagg aatatcgtta cccgtccact tgctgccgtt ccactggatc agcatccgtt
    21661 tcggatccca cggtttaccg ttgatatccg ccgaagcacg gttgtacagc acgcgacggt
    21721 tgagcggcca cgcccaggcc catcccagcg tattccccag accggacggg tcggagttat
    21781 cgcggttagc catctggttg ccctgctctg tccagctacc ggtgtagatc cagcaagaag
    21841 atgcggttgt accgtcatca cgcagatgcg caaagctact cagcaactga cctttcttcg
    21901 caatcagcac gccattagca tcatagagat cttccagcgc atagccgttg ttctctttag
    21961 ctacttcgtc agattgcggt tcgtgcggct gcttgtagtt ccagctcatc ttcatcagcg
    22021 gttctacgcc tttaccacct tcggcctggt acagctcgcg caggtgatgg tagatacccg
    22081 ccagaatttc accgtcgtta cgcgcttcgc ccggcgcgtc ctgacctttc cagtgccaca
    22141 gcagccagcg accggagtta gcaatagaac catcttcttc agcaaagcag gtcgaaggca
    22201 gacggaatac ttcagtctga atagacgccg gatcgacatc gttcgactcg ccgtggttct
    22261 gccagaaggt tgaggtttca gtcaccagcg gatcgataac caccatgtac ttcagcttgc
    22321 ttaggcagct caccactttg tttttgtccg ggaaggacgc aaccgggtta aagccctggc
    22381 agaaataacc ggtgactttg ccttcatcca tcatgttgaa atacttgatg acgtcgtagg
    22441 tctggtccca cttcggcagc cagtcatagc cccagttgtt ctctttctgc gcggcatcgc
    22501 catagaaaga tttcatcagg ctaacgaaga acttcggata gttgctccag tagttcacct
    22561 gaccagccag cgtcgctttc ggcgtgttcg cttccagata cgactgcaaa tcaacctgtt
    22621 tttctgacgg cagcgtcaga taacctggca ggctggtaga gagcagacct aagtcagtca
    22681 gaccctgaat gttggagtga ccacgcaatg cattcacgcc gccaccggcc atacccatgt
    22741 taccgagcag caactggatc atcgccatag tacggatgtt ctgcgcaccc acggtgtgct
    22801 gcgtccagcc cagcgcgtac aggaaggtgg ttgtgcgatc cggtgcgctg gtggaggcca
    22861 gcacttcaca cactttcagg aagtcggctt ttggcgtacc gcagatgttt tcaacgacgt
    22921 ctggcgtgta gcgggaaacg tgctctttca gcaggttcca cacacagcgc ggatgagtca
    22981 gtgtttcatc gcgtttcgca tagccgtttt catcgaactg atagttccag gacgatttgt
    23041 cgtactggcg tttttcagcg tcataaccgc tgaacaggcc atcttcgaaa gcaaaatcat
    23101 cacgcaccag caggctggcg ttggtgtaat gtttaacgta ttcggcgttg attttgttgt
    23161 tttcgatcag gtagcgcaaa acgccagaca ggaacgtaat gtccgtaccg gaacgaatag
    23221 gtgcgtaaat atccgccaca gaagcggtac gcgtaaaacg aggatcgaca acgatcaagg
    23281 ttgcatcgtt gttgtttttc gcttccatcg cccagcggaa accgacggga tgcgcttcag
    23341 cagcgttacc gcccattacc attacgacgt tagcgttttt gatatccacc cagtggttgg
    23401 tcatcgcacc gcgaccaaat gttggagcaa gacttgctac cgttggtccg tgtcagacgc
    23461 gcgcctggtt gtctaccgcc agcatcccga gggagcgggc aaatttctgt gtcagcatcc
    23521 cggtttcgtt gctggcaccg gaggcacaca gcataccggt agaaagccaa cggtttaccg
    23581 ttacgccctg ctcgttcttt tcaataaagt tagcgtcacg gtcagctttc atcagctttg
    23641 caatacggga gaatgcttct tcccagctaa tgcgctgcca tttgtcagaa cctggcgcac
    23701 gatattccgg gtagcgcaga cggttttcgc tgttgacgta atccagcaaa ccggcccctt
    23761 ttgggcacag cgcaccacgg cttaccggat gatccgggtc accttcaatg tgataaatcg
    23821 cttctctggc gtttttcgcg ccatcaccca ggctatacat caatagcccg caacctacgg
    23881 aacagtatgt gcaggtgtta cggatctctt tagcgcgtaa taatttgtag tttcgcgcct
    23941 gagccagtgc ttgcttcggg gcaaagccca atgccgctac cgttgttcca gccataccgc
    24001 ccgcgcagat tttaaaaaat tgtctgcgac tgacgtccat tgctttcctc ttttttcagg
    24061 ggtattactg cgcgaggaaa ctaacagtaa aattctgaat ctttttgcgc gaaatcaaaa
    24121 agaacacgtg tttgccacaa aataatccgc ctgcgcaaat tgacctacct caatagcggt
    24181 agaaaaacgc accactgcct gacaggccag ttaaaaaaat gctataaaat tcagcttaat
    24241 ttttaacggc aagagagaca aaacagcgag catgacacga caaaaagcaa cgctcatagg
    24301 gctaatagcg atcgtcctgt ggagcacgat ggtaggattg attcgcggtg tcagcgaggg
    24361 gctcggcccg gtcggcggcg cagctgctat ctattcatta agcgggctgc tgttaatctt
    24421 cacggttgga tttccgcgta ttcggcagat tccgaaaggc tatttactcg ccgggagtct
    24481 gttattcgtc agctatgaaa tctgtctggc gctttcctta gggtatgcgg cgacccgtca
    24541 tcaggcgatt gaagtgggta tggtgaacta tctatggccc agcctgacaa ttctctttgc
    24601 cattctgttt aatggtcaga aaaccaactg gctgattgta ccaggattat tattagccct
    24661 ggtcggcgtc tgctgggtgt taggcggtga taatgggtta cattatgatg aaatcatcaa
    24721 taatattacc accagcccat tgagttattt cctggcgttt attggtgcgt ttatctgggc
    24781 agcctattgc acagtaacga ataaatacgc acgcggattt aacggaatta ccgtttttgt
    24841 cctgctaacg ggagcaagtc tgtgggttta ctattttctc acgccacaac cagaaatggt
    24901 atttagcacg cccgtcatga ttaaactcat ctctgcggca tttaccttag gatttgctta
    24961 tgctgcatgg aatgtcggta tactgcatgg caatgtcacc ataatggcgg taggctcgta
    25021 ttttacgccc gtactttcct cagcgcttgc agccgtgctg ctcagcgccc cgctgtcgtt
    25081 ctcattctgg caaggcgcgc taatggtctg cggcggttcc ctgctctgct ggctggcgac
    25141 acgtcgtggt taaaataatt gccgggtcta cggcccggca gttaatcaga taaattccga
    25201 caatattaaa aaataaattt caaataccag taattcacct tatatctcat ttcgacttcg
    25261 atcacatatc gataaataat at
//
LOCUS       DAZUDJ010000070        24623 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.070, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000070 DAZUDJ010000000
VERSION     DAZUDJ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24623
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.070"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..561
                     /locus_tag="ACHY1N_003839"
                     /pseudo
     CDS             1..561
                     /locus_tag="ACHY1N_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414844.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(804..1499)
                     /gene="ykgG"
                     /locus_tag="ACHY1N_003840"
     CDS             complement(804..1499)
                     /gene="ykgG"
                     /locus_tag="ACHY1N_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HFS4046056.1"
                     /translation="MDNRSEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTALNQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGAENISQAEQAKVGVVYAEYGLTESGGVVLFSAAERGRSLSLLP
                     ESSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     gene            complement(1492..2919)
                     /gene="ykgF"
                     /locus_tag="ACHY1N_003841"
     CDS             complement(1492..2919)
                     /gene="ykgF"
                     /locus_tag="ACHY1N_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LutB/LldF family L-lactate oxidation iron-sulfur
                     protein"
                     /protein_id="HFS4046057.1"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVWFAKTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDSVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEANGESFRSWFKKHLAQEKKNG"
     gene            complement(2930..3649)
                     /gene="ykgE"
                     /locus_tag="ACHY1N_003842"
     CDS             complement(2930..3649)
                     /gene="ykgE"
                     /locus_tag="ACHY1N_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HFS4046058.1"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAE
                     KVAARMQDLTSFIVNKLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVVHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     gene            complement(4176..5030)
                     /gene="rclR"
                     /locus_tag="ACHY1N_003843"
     CDS             complement(4176..5030)
                     /gene="rclR"
                     /locus_tag="ACHY1N_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine-specific transcriptional
                     regulator RclR"
                     /protein_id="HFS4046059.1"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFLAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMLEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSREMLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
     gene            5256..6581
                     /gene="rclA"
                     /locus_tag="ACHY1N_003844"
     CDS             5256..6581
                     /gene="rclA"
                     /locus_tag="ACHY1N_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine resistance oxidoreductase
                     RclA"
                     /protein_id="HFS4046060.1"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
                     NNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHNENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKQLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGRRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRILGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILHDQIFTHPSMSESLNDLFSLVK"
     gene            6690..6926
                     /gene="rclB"
                     /locus_tag="ACHY1N_003845"
     CDS             6690..6926
                     /gene="rclB"
                     /locus_tag="ACHY1N_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine resistance periplasmic protein
                     RclB"
                     /protein_id="HFS4046061.1"
                     /translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     DTIADIARKYNASSWKVTSMRIDNNSTATAVLYK"
     gene            6938..7531
                     /gene="rclC"
                     /locus_tag="ACHY1N_003846"
     CDS             6938..7531
                     /gene="rclC"
                     /locus_tag="ACHY1N_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species resistance protein
                     RclC"
                     /protein_id="HFS4046062.1"
                     /translation="MEKYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSAREILKQRSNESSSTLKTEY"
     gene            complement(7691..8560)
                     /locus_tag="ACHY1N_003847"
     CDS             complement(7691..8560)
                     /locus_tag="ACHY1N_003847"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308365.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFS4046063.1"
                     /translation="MEFSVLSNNLKMPMMGFGVFQVTDKNVCKQSVLNAIRTGYRLID
                     TAAVYGNEDAVGEAVREAISEGLCTRDELFITSKLWVQDMLNQDTAAAGIEASLKKSG
                     LEYFDLYLLHQAMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLAKFCETVRVKPMV
                     NQVELHPYFAQPEALATMKYYNVQPEAWAPLGGGRHKPFENNLLQSIADAHQKSISQV
                     ILRWNIQRGVVVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLGYVGESVKHFNP
                     EFVRGCLAVKIHD"
     gene            8809..9666
                     /locus_tag="ACHY1N_003848"
     CDS             8809..9666
                     /locus_tag="ACHY1N_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4046064.1"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLTAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRV
                     YRHRDYWDLANIFPSFLIRQQQKTECRLVNFPETPIFGNSFKYDIEVSNKSPDEEVKL
                     RRHHLARCMNNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCKQTDSEMPKEWTINRG
                     LYASFRYEGEWEHYPEWARNLYLMELPARGLARVNGSDIERFYYNENFVEIDSNNIVC
                     EIFIPVRPV"
     gene            complement(9787..14040)
                     /gene="fdeC"
                     /locus_tag="ACHY1N_003849"
     CDS             complement(9787..14040)
                     /gene="fdeC"
                     /locus_tag="ACHY1N_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter adhesin FdeC"
                     /protein_id="HFS4046065.1"
                     /translation="MSRYKTGHKQPLFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     AHAQHAVQPRLSMENTTVTADNNVEKNVASFAANAGTFLSSQPDSDATRNFITGMATA
                     KANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRE
                     RRMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLK
                     NVQWEAPSLLAEGGKITGQGSQWQVTLPAYRPGKDNYYAISAVAYDNKGNASKRVQTE
                     VVITGAGMSADRTALTLDGQSRIQMLANGNEQRPLVLSLRDAEGQPVTGMKDQIKTEL
                     TFKPAGNIVTRTLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDGMS
                     KTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDTDGNPVTGEASRLR
                     FVPQDTNGVTIGTISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTVKDAYDNPVTSLTPEAPSLAGAAAVGSTASGW
                     TNNGDGTWTAQITLGSTAGELEVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLIAKDAHGNAISGLSLSASLTGTASEGATVSSWTEKGDGSYVATLTT
                     GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKAPTVKTTTELTFTV
                     KDAYGNPVTGMKPDAPVFSGAASTGTERPSTGDWTETSNGVYVATLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVDNQLANGQSTNQVTLTVVDTYGNPL
                     QGQNVTLTLPKGVTSKTGNTVTTDAAGKADIELMSTVAGEHSITASVNNAQKTVTVKF
                     KADFSTGQASLEVDSAAPKVANGKDAFTLTATVEDKNGNPVPGSLVTFNLPRGVKPLT
                     GDNVWVKANGEGKAELQVVSVTAGTYEITASAGNSQPSDTQTITFVADKATATVSGIE
                     VMGNYALADGKAKQTYKVTVTDANNNLVKDSEVTLTASPASLNLEPNGTATTNEQGQA
                     IFTATTTVAATYTLKAQVSQTNGQVSTKTAESKFVADDKNAVLTASSDMQSLVADGKS
                     TAKLEVTLMSANNPVGGNMWVDIQTPEGVTEKDYQFLPSKNDHFVSGKITRKFSTSKP
                     GVYTFTFNALTYGGYEMKPVTVTITAVDADTAKDEEAMK"
     gene            14593..14682
                     /locus_tag="ACHY1N_003850"
                     /pseudo
     CDS             14593..14682
                     /locus_tag="ACHY1N_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308358.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15156..15257
                     /gene="ykgR"
                     /locus_tag="ACHY1N_003851"
     CDS             15156..15257
                     /gene="ykgR"
                     /locus_tag="ACHY1N_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small membrane protein YkgR"
                     /protein_id="HFS4046066.1"
                     /translation="MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY"
     gene            15621..15884
                     /gene="ykgM"
                     /locus_tag="ACHY1N_003852"
     CDS             15621..15884
                     /gene="ykgM"
                     /locus_tag="ACHY1N_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFS4046067.1"
                     /translation="MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPY
                     VTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     gene            15884..16024
                     /gene="ykgO"
                     /locus_tag="ACHY1N_003853"
     CDS             15884..16024
                     /gene="ykgO"
                     /locus_tag="ACHY1N_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HFS4046068.1"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     gene            complement(16059..16284)
                     /gene="ykgL"
                     /locus_tag="ACHY1N_003854"
                     /pseudo
     CDS             complement(16059..16284)
                     /gene="ykgL"
                     /locus_tag="ACHY1N_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414829.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein YkgL"
     gene            17108..17650
                     /gene="ecpR"
                     /locus_tag="ACHY1N_003855"
                     /gene_synonym="matA"
     CDS             17108..17650
                     /gene="ecpR"
                     /locus_tag="ACHY1N_003855"
                     /gene_synonym="matA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECP biosynthesis operon DNA-binding
                     transcriptional regulator EcpR"
                     /protein_id="HFS4046069.1"
                     /translation="MECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKD
                     FVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAG
                     LSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTV
                     YTHRRNAEAKLYSKIYKLVQ"
     gene            17725..18312
                     /gene="ecpA"
                     /locus_tag="ACHY1N_003856"
                     /gene_synonym="matB"
     CDS             17725..18312
                     /gene="ecpA"
                     /locus_tag="ACHY1N_003856"
                     /gene_synonym="matB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="common pilus major fimbrillin subunit EcpA"
                     /protein_id="HFS4046070.1"
                     /translation="MKKKVLAIALVTVFTGMGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            18374..19042
                     /gene="ecpB"
                     /locus_tag="ACHY1N_003857"
                     /gene_synonym="yagY"
     CDS             18374..19042
                     /gene="ecpB"
                     /locus_tag="ACHY1N_003857"
                     /gene_synonym="yagY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpB"
                     /protein_id="HFS4046071.1"
                     /translation="MKKHLLLLALLLSGISPAQALDVGDISSFMNSDSSTLSKTIKNS
                     TDSGRLINIRLERLSSPLDDGQVIAMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     gene            19068..21593
                     /gene="ecpC"
                     /locus_tag="ACHY1N_003858"
                     /gene_synonym="yagX"
     CDS             19068..21593
                     /gene="ecpC"
                     /locus_tag="ACHY1N_003858"
                     /gene_synonym="yagX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher EcpC"
                     /protein_id="HFS4046072.1"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDHGQLRIRKIQLEESEDNASV
                     SEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNFGIYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRPQRVNKLFSRGRGVGAPLAWQVWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTLSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSNIASI
                     SATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
                     RYNSHYYTADYYQNVYSGPFGSLGLRAGIQRYNNGDSNANTGKYIALDLSLPLGNWFS
                     AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
                     ASGTLNVNSAADGYVNTNLTANGSVGWQGKNIAASGRTDGNAGVIFNTGLEDDGQISA
                     KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVI
                     EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
                     GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
     gene            21583..23226
                     /gene="ecpD"
                     /locus_tag="ACHY1N_003859"
     CDS             21583..23226
                     /gene="ecpD"
                     /locus_tag="ACHY1N_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial adhesin EcpD"
                     /protein_id="HFS4046073.1"
                     /translation="MRVNLLIAMIIFALIWPATALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYNGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYLQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSQESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            23195..23905
                     /gene="ecpE"
                     /locus_tag="ACHY1N_003860"
     CDS             23195..23905
                     /gene="ecpE"
                     /locus_tag="ACHY1N_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414823.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpE"
                     /protein_id="HFS4046074.1"
                     /translation="MFRRRGVTLTKALLTAVCMLATPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKNARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPRDNRERYYRVSFREVPTRNQTRRSPTGGEVSTEPVVVMDTILVVRPRQVQFKWS
                     FDKVTGTVSNTGNTWFKLLIKPECDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            24218..24547
                     /gene="ykgJ"
                     /locus_tag="ACHY1N_003861"
     CDS             24218..24547
                     /gene="ykgJ"
                     /locus_tag="ACHY1N_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HFS4046075.1"
                     /translation="MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPF
                     HRCMSGTNQKNPRCIALAGTPGKNACCTIYKNRSSTCREFAMSGENGVVNEACNRARA
                     KYGLTPL"
BASE COUNT         6528 a         6126 c         5593 g         6376 t
ORIGIN      
        1 cttttatttc tgtatatcaa taaagataat ataaaagtga gttacagcct aaaaataaac
       61 cagacaacac cagacatact tgttaactgt gatagcaata ataactttgc ctgtcagacc
      121 gcaatgacta aagatgttat acagcgaatt actacatttt ttcacaccag cccagatgtc
      181 aagaacagag aaataaagct ggaatggtca tgagataaga gagatttacc aactgctgaa
      241 tcggaaatat ctcgcgtgca ggcgtctatt atcaaatggt atgcgtcaga ataccataat
      301 ggcaggcaag ttctcgatga gatacaaata ccttcagcaa ttaacagtga gctttataca
      361 aaaatgatat acctgaccag gaactggtca ttgtatccga acggtgatgg ctgtgtaact
      421 ataagctcac cagaaataaa aaataaatac cctgctgcca tttgcctggc tctgggattt
      481 tttctaagca ttgtaatttc tgtaatgttt tgccttgtca aaaaaatggt agatgaatac
      541 caacaaaact ctgggcagta ataaacaaca ttctgataga gagtgcctgt ataaagctga
      601 agtgacaatg accgggaagg gaacccgttt tcaggaatgg atgcctgtct ttttcactgt
      661 aaatatcctg gcattactaa tgccaggata tttacagaag agcagcataa ccatgacgga
      721 acggggttaa gtcaggttgt ccttaacgct attttcaacc tcgtatgcct tcttcaggtt
      781 tatgttcaga tctcatatct ctctcagcaa tcctcaataa tcagatacac cgctttcacc
      841 gggccatgaa ccccgacgac tttgataagc tcaatatccg ccgttgaact agggccgcta
      901 atgatgttaa tgcaggacgg cattcgttca ccggcctgcg ctttctgatg caatttttct
      961 gcgagttgcg ctacacgcgg caggattgtg cttttacgca ggataaaaag agaagattcc
     1021 gggagcaggc tcaatgaacg cccgcgctcg gcggcggaaa aaagaaccac gcctcccgat
     1081 tcggttaaac catattcagc atacacgaca cccactttag cctgctctgc ctgcgagata
     1141 ttctcggcac ctttcgccgg atcccaaaca acggcattgc attcctgctg caaacgttcg
     1201 ctaatcccca attcctctag cctcgtgtca ccgctaatca cgaccgactg atctcccagc
     1261 tctttacaca gacgtattgc agcttctgcc gccttcgcct cgctggtcag ctcacagcgc
     1321 gtcaacataa catcgctggc aaactgaata aacgcgtcac agcgctgctg ttggttaagt
     1381 gcggtaagcc gctcgttagc atagttgtta agcggcgcat cttctgcttg cggttcaagt
     1441 cgcaacgggc gacccagtgc ctgagcaacg ttattcaaaa attcgctccg attatccatt
     1501 ctttttctcc tgcgccagat gtttcttaaa ccaactacgg aaactctctc cgttagcttc
     1561 aggaagatcg cgtgcttcca tccagtcact aatcgcgcca aatttgagtg gtgttttgcc
     1621 gccattgata aaccagcttg ccgcatgagc accggccatc atcccgactt tccacaatcc
     1681 tggatgacta ttggcataag cgaacatttt tatcgcccgt tgctctgctt ttgcggtgat
     1741 ccctttttca gccatcaccc gacgatgacg caaaatcagt tttgacagcg gaatacgcac
     1801 cggacacacg ctgtcacaag cagtgcataa agagcaggcg tagggtaaat ctttaaaatc
     1861 tttatagccg ccaagtagcg gagaaatcac cgcaccaatt ggccctggat aaatagagcc
     1921 atatccatga ccgccaatat ggcgatatgc cggacaagta ttcatacaag ccccgcagcg
     1981 aatacagcgc agcacatccc gaaattcaga ggccagcacc tcagaacgcc cgttatcgac
     2041 aataaccaga tgaaactctt caggaccatc aacgtgcccc gcttcgcgcg gtcctgtcag
     2101 ccaggtgttg tatcccgtca aacgtgcacc aacggcactg cgcgccagca tggtgatcaa
     2161 tacatctacc tcggcaaacg tgggggcaat acgctccatt cccatcactg caatatgcgt
     2221 tttaggcagc gtggtacaca ttcgcgcatt accttcattg gtcaccaggc ataccgaacc
     2281 tgtctctgcc accgcgaaat tacagccggt aatacctatt tcagcactga ggaaatcttc
     2341 gcggattttt tgccggatga ataaggtcat cgcttcaggc gtttccggcc cctcatagcc
     2401 cagacgttcg tgtagcactc gacggatctg atggcgatct ttatgaattg ccgggaccac
     2461 aacatgagat ggcggatctt gatccagctg gagaatatat tcacccagat cggtttcaat
     2521 cacctgaatg ccagcatcct gcaacacatg attgacacca atctcttcgg tcaccatcga
     2581 tttagatttc accaccttcc gggcattttt gcgttgggca acctgtaaaa tgtagcgggt
     2641 agcgtcttct ttggtttttg caaaccagac gtgaccgccg ttttgcgtca ctttttctga
     2701 gagctggtac agataagcgt cgagattact cagaacatga tcacgtatct gggcggcccg
     2761 atcgcgccac tcctcccagt gccccaattc atcgaccatt ttttgccgat ttgccccaat
     2821 acgctgctgc gcgtttgcca ccgctttgcg catgatcgga tcttcaattt gctgacggat
     2881 gcgtgtctta aaatctgtat tactggtttt gatcgacatc tttatatcct cagcggctca
     2941 tcaacacttc agcaatatgc atcactttga ctttctgccc ttcccgttgt aatcgcccac
     3001 tgatgttcag caggcaactc acgtcagcac caattaaata ctcagggcgg acttccatca
     3061 ggtgcacaac cttttctttc accatctcgc cggatatttc ggccattttg accgagaacg
     3121 tgccgccaaa tccgcagcag gtatcctgtt cagcaaaggt caacagctcc agtccacgca
     3181 catttttcag cagcgtaagt ggctcgtcct tcactcccag cttacgggcc aggctacaag
     3241 atgggtgata tactgctctc ccttgcaaac tggcacctac atcgactacc cctaatttat
     3301 taacaataaa agaggtgaga tcctgcatac gcgcggcaac cttttcggca cgtgatgccc
     3361 attcaggttc atccgccaga tacgtcgggt aactttttac ggcataggtg caagagccag
     3421 ccggtgaaat aatgggatcg tcgttatcct ccagtgcggc gatcagattt ttcatccctg
     3481 gaatcgcttc tttgatataa ccgctattga tcgcaggctg accgcagcat ccctgtttct
     3541 ccgggaaatt tacgcgacag ccgagttttt ccagtagcag cacggagtct cgtgccattc
     3601 ttgatttcag ggcgtcacca atacaggtga caaagaaatt gacattcaca actaatactc
     3661 cattacttca tgcccattta tgcccgatgt ttccccccca ccgggggatc aatcatcaat
     3721 aaatatggcg ttctttttta attggctagc aacataccac ccctcatttg tatgacaaat
     3781 gataatcttt catccaaact tcaaatgcaa taactaattt tatttctttc ggcatcgctc
     3841 acattttatg gggaaatcga cgttcatttt tggcataaga aatccattta aaaaggctac
     3901 atcccttata cctattcaga gctacttatt caggggttat tgagatatac actgatggtg
     3961 tacaaaaaaa tcaccgacaa taatcacgta tcaagtaata gtcggggttt tatttaattg
     4021 aagcaattta gtttgcattt ttatttaaaa actgagctag agtccatcag aaaaaaatat
     4081 ataaagccca aaccaccgtt ggaaatagaa atagttgaaa ggctcacaac tcccggaatg
     4141 cggattatct ttgccctgat ttctggcggt tttattcagg gtgcaagctg tctgaccctt
     4201 tcccgatatt ctcccggagt acaaccaaac tcgcggacaa acgccttgtg aaaagatgat
     4261 tcactggcat agcctactga ctcagcgatc accacaacag ggagcatttc ccgggaaaac
     4321 atctgggccg ctatttgtag acgcaacttt gttaatacag ccagcggcgt ggttccggaa
     4381 acatcacgga aaagctgggc aaaacttgcc cgggacatgt gagcgatgct ggccagcgat
     4441 tcgacggtcc aggcgtgtcc tggcatttcc agcatttgct gtattaccgc accaagacgt
     4501 ggatgcagaa gcaaactgag aatgtttttc tcagtattaa cctgtgcaat ccactcacgc
     4561 accgcgaggg taaagaatgt agcgcagatc tggctacaca gtgcatccac tcccggcatc
     4621 gccgatctgg attcctgttg taaaaacggg atcgcctccc tcagccagtt atattccacg
     4681 ctgtggttaa ccggtgctaa aaacagcgtt tccggcaaag acgttaaaaa ataacgcgcc
     4741 gaatgttgca accgaagagt gccgcagaca atacaggtcg attcattatc gacatgactc
     4801 aggcgatgag ctgaattttg tggtagcagg accacatttc ccgggcgtaa tgtaaaaatc
     4861 tctcccgtcg gcatttccag cttcgccgct ccttgcgtta acgcatgcca acgaataacc
     4921 gataattccc cggcaccatg tggaagctgc cagtcacttc ctaacacgca attcttatcg
     4981 atcgttcctt gtggagcgtt aagcatcaac aaacggctaa gggcatccat atcagactcc
     5041 tgagtggttt ttgattacaa acaccaacaa tcttagtaaa taactaatct aataccatca
     5101 aatggttaat catgattttt gttttgtgat tctgattaag aaaaagaaaa taccagacga
     5161 taagacaaaa tatcaagcgt tgtgaagaaa tggtatttgc tcttttgcgt ctatagtcat
     5221 gatgtcaaat gaacgcgttt cgacaggaaa tcatcatgaa taaatatcag gcagttatta
     5281 ttggttttgg caaggctgga aaaacattag ccgtcacgct ggcaaaagca ggttggcgag
     5341 tggctctcat cgaacaatca aatgcaatgt atggcgggac ctgtattaat atcggctgca
     5401 tcccaaccaa aacattggtt catgacgcac agcagcacac agattttgtc cgtgccatac
     5461 agcgtaaaaa tgaagtggtt aattttttac gtaataagaa ttttcataat cttgcggata
     5521 tgcccaatat cgacgtgatc gacggccagg cggagtttat caataatcat agcctgcgtg
     5581 ttcatcggcc tgagggaaat ctggaaattc atggcgagaa aatttttatt aataccggtg
     5641 cacaaaccgt ggttccgcca attcctggaa ttaccaccac gcctggtgta tatgacagca
     5701 ccggattact taatctaaaa gaattgcctg ggcatttagg tattttgggc ggcggatata
     5761 ttggcgttga gttcgcctct atgttcgcta attttggcag caaggtaacc attttagaag
     5821 cagcttcgct gtttttgcct cgggaagatc gggatattgc tgataatatc gcgacgattt
     5881 tacgcgatca gggcgtcgat attatcctca atgcccatgt ggagcgaatc agtcacaatg
     5941 aaaatcaagt gcaagtgcat agcgagcacg cccaactggc ggtggatgca ctgttaatag
     6001 cttccggtcg tcaaccggct accgcttcgt tacatccaga aaatgccggt atcgcagtaa
     6061 acgagcgcgg ggcaattgtc gttgacaagc aattacatac caccgcagac aatatttggg
     6121 cgatgggaga tgttaccggc gggctgcaat ttacttatat ttcactggat gattaccgca
     6181 ttgtgcgtga tgagttgctg ggagaaggca gacgtagtac tgatgatcgg aaaaatgtgc
     6241 cttattccgt attcatgaca ccgccactgt ccagggttgg tatgacagaa gaacaggcca
     6301 gagagagtgg tgctgatatt caggtggtga cattgcctgt agctgcaatt ccgcgtgcca
     6361 gagtgatgaa tgatactcgt ggggtattaa aagcgattgt tgataataaa acccaacgta
     6421 tattaggggc atcactgctg tgtgttgact cccacgagat gattaatata gtgaaaatgg
     6481 tgatggatgc cgggctgcct tatagcatat tacacgatca gatatttact catccgtcga
     6541 tgagcgaatc actcaatgat ctattttcat tagtcaaata aactcaaaat cagacgccag
     6601 aacaaatatt ctggcgtctc agagaaaaga atcttattaa ttccctgtta ctctataact
     6661 tcttaatcac ttcattgatg gtattttata tgttcaaaaa atctgtttta tttgcaacac
     6721 tattatctgg cgttatggca ttttccacca atgcagatga taaaataatt ctgaaacata
     6781 tcagcgtctc gtcagtatca gcatcaccga cagttctgga ggataccatt gctgatatag
     6841 ccagaaaata taatgcttca tcctggaaag tcacatcgat gcgaattgat aataattcaa
     6901 ccgcaacagc agtattgtat aaataaggat gttcacaatg gaaaaatacc tgcacctgtt
     6961 aagtcgggga gataaaattg gcctgacatt gattcgtctg agtattgcaa ttgtttttat
     7021 gtggattggg ttattaaagt ttgtccctta cgaggcagac agcattacac cattcgtcgc
     7081 aaacagtcca ctaatgtcgt tcttttatga acacccggaa gactataaac agtatctgac
     7141 tcacgaaggc gaatacaaac cagaagcaag ggcatggcaa acggccaata atacctatgg
     7201 tttttccaac ggtcttggcg tcgtggaggt gattattgct ctgctggttt tggctaatcc
     7261 tgtcaatcgc tggttaggtt tattgggagg actgatggca tttaccacgc cgctggtaac
     7321 actctcattt ttaatcacca ccccggaggc atgggtaccc gcattgggtg acgctcatca
     7381 tggtttccct tatttatccg gtgctggtcg cctggtattg aaagatactc tgatgctggc
     7441 aggtgctgtc atgataatgg cagattcggc gcgggaaatt cttaaacaac gcagtaatga
     7501 atccagttca acgttaaaaa ctgaatattg ataatccgaa cactgtctgt tgttcacttt
     7561 ttcaggcgtc aggccccctt tctgatgatg aagcctgacg ccatattacc ggagatatga
     7621 cagagtgaag atcaatatca ctcccctgtt aaaagattct tgtcgtctca ggtaaaatat
     7681 atgattaata tcaatcatgt atttttacag caagacaacc acgaacaaat tcaggattaa
     7741 aatgttttac cgactcccca acataaccca aatcaagcga actaatttgt gccatttctt
     7801 tctctgtcag tgagaaatcc cagatagcaa aattttcttc gatacgctgt tgatgtgtcg
     7861 atttcggaat aacgaccact ccccgttgaa tattccaacg cagaatgact tgagaaatcg
     7921 atttttgatg ggcatctgca atactctgaa gcagattatt ttcaaagggt ttatgtcgtc
     7981 caccacctaa cggagcccat gcttcaggct gcacgttata atacttcatg gttgccagcg
     8041 cctctggttg ggcaaaatag ggatgcaact cgacctggtt gaccatcggt ttaactctta
     8101 ccgtttcaca aaatttcgcc agaacatgag gatagaaatt ggaaacccca attgctttta
     8161 atttgccctc ttcataggca tcttcgagtg cacgccacgc actgaaataa tcgcgcatag
     8221 cctggtgcaa taaatagagg tcgaagtact ctagtcccga tttttttaat gatgcttcaa
     8281 tacctgctgc tgccgtatcc tgattcaaca tatcctgcac ccacaattta gacgttataa
     8341 ataactcatc tcgggtacat aaaccttcag atatagcttc acgaacggct tcaccgacgg
     8401 catcttcatt accgtatacc gctgcagtgt cgatgagtcg ataacctgtg cggatagcgt
     8461 tcaacactga ctgtttgcac acgtttttat cggtaacctg aaaaacacca aatcccatca
     8521 tcggcatttt cagattgtta cttaatacgg aaaattccac tgtcagtccc tccattaggc
     8581 atgaacaatg agtctacgtt aaaacgtaac ctcaaattag tacgtggatt ttgatatcac
     8641 ttatgcaaaa aattcattaa taatgcagga ctgaaacctc tctattttcg gggacaacga
     8701 agcagacgct accagtgctt ttgccttcgc ccttgctgtt tttgatacac ttagggccca
     8761 gggcataacg aaaatgtgcg atatgacgaa gaatcaatgg agaatgtgat gatcaggcag
     8821 aagattctac agcagctcct ggagtggatt gagtgcaatc ttgagcaccc tatttcaatc
     8881 gaagatatcg cacagaaatc tggctacagc agacgcaaca tccagcttct gttccgaaat
     8941 ttcatgcatg tgcctttggg agaatacatt cgcaaacgaa ggctttgtcg tgccgccatt
     9001 cttgtccggc tcaccgcgaa atctatgctt gatattgcac tctctttgca ttttgattca
     9061 cagcagtcat tcagccgcga atttaaaaag ttattcggct gctctccccg tgtataccgc
     9121 caccgtgatt attgggatct cgcaaatatc ttcccttctt ttttaatacg tcaacagcaa
     9181 aagaccgagt gtagattagt caactttcct gagacaccta tttttggcaa ttcatttaaa
     9241 tatgatattg aagtgtcgaa taaatcaccg gatgaagaag tcaaactgcg acgtcatcat
     9301 ttagccagat gtatgaataa ttttaagacg gatatctatt tcgtctccac gtttgaaccg
     9361 tcaacaaaat cggtcgattt gctcacggtt gaaacttttg ccggtacggt atgcaaacaa
     9421 accgattcag agatgccgaa agagtggaca attaaccgag gactgtatgc ctctttccgc
     9481 tatgaaggtg agtgggagca ctaccctgaa tgggcgcgaa acctctatct gatggaatta
     9541 cccgccaggg ggttagccag agtgaacggc agtgatattg agcggtttta ttacaatgaa
     9601 aatttcgtcg aaattgatag caataacatt gtttgcgaaa tttttatccc cgttcgtccg
     9661 gtttagtttt cgctatatct aaatgaattt ataacgagac tactgtcagg aaattcaata
     9721 aataatggcg ttgaagatgt caacgccatt attgtttatt agaatgttac tttcatattc
     9781 ttaaaattat ttcatcgcct cctcgtcctt tgccgtatcg gcatccaccg cggtaatggt
     9841 caccgtcact ggcttcattt cgtacccgcc ataggtcagg gcgttaaatg tgaacgtata
     9901 gacaccaggc ttgctggtac taaatttacg cgtgattttt ccgctcacga aatggtcatt
     9961 tttcgacggc aggaactgat aatccttttc cgtcacccct tccggcgtct gaatgtcgac
    10021 ccacatattc ccgccaacgg ggttgtttgc cgacatcagt gtcacctcca gcttcgcagt
    10081 cgatttccca tccgccacca gagattgcat atcagatgat gcggtgagta ccgcgttttt
    10141 atcatccgca acgaatttag attcggcagt tttcgttgat acctgaccgt tggtctgact
    10201 cacttgcgcc ttgagtgtgt atgtcgccgc aacagtagtg gtagcggtga aaatagcctg
    10261 cccttgctca ttcgttgtcg cagtgccatt cggttccagg tttaacgaag ccgggctggc
    10321 agtcagcgtc acttcgctat ctttcaccaa attgttattg gcatcagtca ccgtaacttt
    10381 atacgtttgt ttggctttgc cgtccgccag cgcatagttg cccatcacct caataccgga
    10441 gacggttgcg gtagccttat cggctacaaa cgttatagtc tgcgtatccg aaggctggct
    10501 attccccgcc gatgccgtga tctcatacgt tccggcagtc actgaaacca cctgcaactc
    10561 tgctttcccc tcaccgttgg ctttcaccca gacattatcg cctgtaagcg gcttgacacc
    10621 ccggggcaga ttaaaggtca ccaggctccc tggaacaggg ttaccatttt tatcctcaac
    10681 ggtcgccgtc agcgtaaagg catctttgcc gtttgccact tttggcgcgg cgctatcaac
    10741 ctccagactc gcctgaccgg tactgaaatc cgccttgaat ttcaccgtaa ccgtcttctg
    10801 agcattattc actgaggccg tgatgctgtg ttccccggca accgttgaca tcagctcaat
    10861 gtcggcttta cctgccgcat cggttgttac cgtattcccc gtcttgctgg tcacaccttt
    10921 cggcagagtc agcgtcacat tttgtccctg caacgggtta ccataggtgt ccacaacggt
    10981 cagggttacc tggttagtcg attgtccatt agccagctgg ttatcaacct tcaccgtcat
    11041 atcacgaatc tcagccttag atgcgtcacc agcaacattc agcaccagtg gctgagcaac
    11101 ggcattttgg ccgttcactc gcggcatcac agacaactgg cccgcggcag atcccagagt
    11161 caaggtcgcc acgtagaccc cattacttgt ttctgtccag tctcctgttg aaggtcgctc
    11221 tgtccccgtg ctggcggcac cgctaaacac tggtgcatct ggcttcatcc cggtgaccgg
    11281 gttcccgtac gcatccttca cggtgaaggt gagttccgtc gtcgttttga cggtcggagc
    11341 cttattgtcc gcaacaagcg tagagttcgc tgatgacatc tctccggcga tgaccgtcaa
    11401 ctgcgcggct tcggtggctg ctggctggcc gttgaatagc ggcatgacac gaagctcgcc
    11461 cgtctttccg cctgtagtta acgtagcaac ataggaaccg tcaccttttt cggtccaact
    11521 ggaaacggtc gccccttcag aggcggtccc cgtcaaactt gccgacaacg aaagaccact
    11581 gatagcgttg ccatgtgcat cttttgcaat aagcgtcacg gttgtacttt cgccggcttt
    11641 tacgtgatct tctgcgacag agactttcga ctggtttgaa gataacgcat cagccaccac
    11701 ggttactttt gccgcatttg ctgccgcatc ctgtccattt agcttcggca taacttctaa
    11761 ttcacccgcc gtagagccga gagtaatctg cgcagtccac gtcccatcac cattatttgt
    11821 ccagcccgat gccgtagaac ctacagcagc ggcacccgct aatgacggcg cttccggcgt
    11881 gaggctggtc acagggttgt cataggcatc ttttaccgtc cagattgccg taactgtacc
    11941 cccaaccacc ggtttatcag gattcagggt gatggacgaa tgtgctgcat caagcggccc
    12001 ggcaacaaac ttcagcgttt gttgtaatgt gcccagctga tactgctcgc tgaaagcacg
    12061 cacaacaacg tttccggcac gggtcgaaga aaccgtagcg ctgtaaacgc ctggttttat
    12121 ctccgaaatt gtaccaatgg tgacaccatt agtgtcttgc ggaacaaatc gcaagcggct
    12181 ggcctctccc gtcaccgggt taccatcagt atccaccgca gtcagcgtca gcgtgtaggc
    12241 ttgctgacca tcagcaacca cgtcacctga cggctcgtta gcgctcaggg tggagtttgc
    12301 cacatccatc atcgtggccc gcagttctgc agtgacggtt ttgctcatgc catcaacact
    12361 aacagtaatc gttgcctcac ctgactgcgt tccggtagta aagacagact gatacacccc
    12421 tgcttcagtt tcggtgaact cacccagtgt tggctttgcc tgtgatttag tggccttcag
    12481 ggtacgagtc acaatatttc cagccggttt gaaagttagt tcagtcttga tctgatcttt
    12541 catgcccgtg actggctggc cctcggcgtc gcgcagagac agcaccagcg gtctttgctc
    12601 attaccgtta gcaagcattt gaatacggct ctgaccgtca agcgttaacg ccgtgcgatc
    12661 ggcactcata cctgctccgg taatgaccac ctctgtctgc acgcgttttg aggcattgcc
    12721 tttgttatcg taggcaaccg cagaaatcgc ataataattg tctttgcctg gacgataagc
    12781 cgggagcgtt acttgccact gactaccctg accggtaatt ttgccacctt cagccagtaa
    12841 tgacggcgct tcccactgca catttttcag tccgtgagtt gctttgctga ccacaagccc
    12901 cagggaaagt gtctgaccgc ccttaccttc aatacgctca ggcagagcaa tacggatcac
    12961 ttcagatttg cggtactcaa gaacgatgtt gttattacgc tcaaccaggt catagcggct
    13021 gcctgccagc attcgacgct cgcgaatgct gtctgtatcg agttgtttct ccagaggttc
    13081 gccaatccga taattaactt ccaggccaaa gcgagtgtca ttctcaccgc tcttgccctg
    13141 cttatgcccg gcgctcagtg tcagaagagg cactggcgta taggtcacct cggcagaaat
    13201 agcatgcggg tctttctggc gcttatcttt accaaacagc ccgacttcat cgccataata
    13261 ctgttcatac atcaggcttg cgccaagctg cggccaggca ggtaaatagc cctctgcgcg
    13321 gatatcccaa ccattcgccg ggcgttcctg ataatcctca atatccggcg attttttcca
    13381 gccagaagcc cgaatataac cattggcgct cagtttcaga taatcgcgcc agtattccgc
    13441 accaacacca atgcgggtat gactacggga taaatcatga tcgataaaag tattcacccc
    13501 cgccatccag tcatttcctg aaaaatgacg ccagccaaaa ccaatatttg actgagtacg
    13561 atcgtctgta cgatgtattg ccccctgagt gaacaacata tttgtcggcg tatcataaat
    13621 cggataaagc atttccagcg aagaatcctt cagcgagaaa tctttatcga cattcagttt
    13681 gacgcgcgct gtaccatatt tcccgagcca ctcctgtatt tcctggttag ctttagcggt
    13741 ggccattccg gtaataaaat tacgtgtcgc atcgctatct ggctgactgc ttaaaaatgt
    13801 cccggcattt gcggcaaacg acgcgacatt tttctccaca ttattatcag cagttaccgt
    13861 ggtattttcc atgctcaacc gtggctgaac cgcatgctgc gcatgtgccg ccattactgg
    13921 ggtaaaggtg acagcgagtg gaaaaagaac ctgaacagag atatttgccc acgccacgca
    13981 gcgggccaga actgaataac gaaatagtgg ttgtttatga cctgttttat aacgtgacat
    14041 tgagataatt tcctgatgaa cgaattaacg aacataggca gacacaaata atggcgtctg
    14101 cttgtcagaa aaaccggaga tttcccggtt tccttttccg cagaaaagga aataccttta
    14161 tgtaagaaag tacaccgcca cctaatatat ccagtgcctg tagccactca tcaggtggtt
    14221 gggcgcggga ttatattttt atttatgggt aaaaatttag ctttttgtgc aagtcattaa
    14281 atagatacct aagttatatt tcttactctg cggacagtga ataattcatt attcagagtg
    14341 aataataatg acctgtcttt aatttaccac gattggcaat acatcgaagt aggtatatac
    14401 gccaggataa accaatatat tttttatgga tattcatttt cattcatcag actgtaaatt
    14461 gcggagatat cgaacttgca ctacccatcg caacactcaa acagatttat gaatttcgtt
    14521 cataacccct gacaaatcct gccgtctaat cgagcttttc cctttacgtt atgcttctca
    14581 tgaacgataa cacaacttgt tcatgaatta accattccgg ataaactatg ggatcaaatt
    14641 caggcatcga aaggaactga ctggtttccg ttaatgaatt aaatatctat tactctcccg
    14701 agagtaaaac tatcaaacca atgagtaacc gatacagcct cgcaaattct ttcagataat
    14761 taacccgtca ctgcggcacg ttctctcgta aggcgtgcct gcagtgtaat ccagtatgta
    14821 tccggcatag ttgacggttt aatagaactc aattcctctc ccaggtcacc aacaacgata
    14881 tcttgtataa caccccagga gatacgacat tatgatgaga tgcgatatgc tcctcagcgc
    14941 caatcaacgc ccggactggg ccagtcttga gatcagactc attcccggaa ctgacttcag
    15001 gcgacatata tcaatgacgt tggtgcaata aaagatagcc gatgtaatac atccattcaa
    15061 atttgtgata catgtcaaaa aattggttga ccaaactcgt tatttatata agggcactta
    15121 cgaagtgcgc tcttttttaa agcgaggaag taccaatgaa agagaataaa gtacaacaaa
    15181 tcagtcataa actgattaat atcgttgttt ttgtcgcaat tgtagaatac gcctatttat
    15241 ttctccattt ctattaataa cggcaataaa ctgttcactt cagtgatatt taaaatatgc
    15301 atcctctccc tttttgtaag taattattat atccgtggga gaggaataca cgctgtcagg
    15361 taatcaatca tactgcgata aatcatcggc cagtaaagtg gagataacct ccattgtcga
    15421 aaaatccata ctctcagcga aaccatcatc aatcactcat ccaggcgttt atgggagcgt
    15481 cgccaacggc tgctaacaat gccagacttc cccgttgggg aaattccaca taccaaaaat
    15541 gggcacaggg attgggtgtt gaaatgatcc ggatgagcat gtatctttat ggttatgtta
    15601 taacataaca ggtaaaaatg atgaagccca atatccatcc tgagtatcgt actgtggtgt
    15661 tccacgacac cagtgttgat gagtacttta aaatcggctc gactatcaaa acagaccgtg
    15721 agattgagct ggatggcgta acgtatccat acgtgacaat tgatgtctct tcgaaatcgc
    15781 acccgttcta tacagggaag ctgagaacag tggcatcaga aggaaatgtt gcacggttca
    15841 cccaacgttt tggtcgtttt gttagcacga aaaagggggc atgatgaaag tccttaactc
    15901 tctgcgtacc gcaaaagaac gccatccaga ctgtcagatt gtgaagcgaa aaggacggct
    15961 gtatgtgatt tgtaaatcta atccacgttt taaggccgtt cagggtcgta agaaaaaacg
    16021 ttgatttaaa attcgacgaa ttaacgatat ttgtctgatt aataatcaga ccggattaat
    16081 gttggtgtat ttattacacc agcattaatt tttctgggga tgtatcttcc tgttcattta
    16141 aggtcaactg cctgacgttt ctctccgaat attccattat attaatgttg acttgttgac
    16201 cagcttcgcc ctgtatgctg gcatcaaccc tcttttagac tgaacacgcc actcagtttc
    16261 ctccctttgc gacgcagcct gcatttacac tcaaactgtt aagatgataa atgtggtaaa
    16321 tctgttggta ctgacataaa aacgtttacg ccacaggaac ggcctgatcc accggtaacc
    16381 ccatcgccga cgttcgagtg ccagttagag taacgcgcac agatgactga atgcagtgcc
    16441 ctggcaaaga ggccatcgtt cctgtgacaa ctggcagtct tcgtttaact tcacttaatt
    16501 tggctcttag ggggcttacc ggacagatga cgtacttata cctgtttaat ttttcatcac
    16561 ttattgggat gaacacccat aaccattttg tgcggcatgt taatccatta aaacacctta
    16621 ctgattggca aatcatcttt aattatgact catgatagtt ttatattcta tttcttatca
    16681 tttaaacttg tttttttact agtccattac acaacacatt aagactattc ctaacacctc
    16741 agggcaaagt tcctggctaa tataaaatgc aagtaagaat tgaacgttat attgccaata
    16801 accttatgaa actgaatgtc tttttcttct tatcaaaaaa gcaatatttt cagtttttct
    16861 aaatattgac ttaaccattg aattcctttt ctgttcacat attgacactc atcaggaaaa
    16921 aaacataaat ttaaacctaa tcgaaataat taaaacttaa tctcgtttaa cctatattga
    16981 tatgtgctac gtatcttatt tacttccgat ttactaaaga aactgaatgt acctgtaaaa
    17041 attacaggtt tggaaagtag tgacatggca aaatgattac agcagggact atgaggttaa
    17101 aaaccatatg gaatgtcaaa accgttctga taaatacatc tggtctcccc atgacgccta
    17161 cttctataaa ggactatctg aactgattgt ggatatcgac agattaattt atctatcgct
    17221 ggagaaaatc agaaaagatt tcgtgtttat caatctcaat acggattctt taactgaatt
    17281 tataaaccgt gataatgagt ggttatccgc ggtaaagggg aaacaggtcg tattgattgc
    17341 ggccagaaag tcagaagcct tagcaaatta ttggtattac aacagcaata ttaggggcgt
    17401 ggtatacgct ggactgagtc gtgatattag aaaagaactg gcctatgtga ttaatggcag
    17461 gttcctgaga aaagatatta agaaagataa aatcactgac cgagaaatgg aaattatccg
    17521 catgacggct cagggaatgc tgcctaaatc gattgccaga attgaaaatt gtagtgtaaa
    17581 gacagtgtat acccatcggc gtaatgcaga ggccaagctg tactcaaaaa tatataagtt
    17641 ggttcagtaa actccaggca agttagtttt aaaaaatgac tcactgggac atcacgtcct
    17701 caattcaact cgggaagaaa tgcaatgaaa aaaaaggttc tggcaatagc tctggtaacg
    17761 gtgtttaccg gcatgggtgt ggcgcaggct gctgacgtaa cagctcaggc tgtagcgacc
    17821 tggtcggcaa cagccaaaaa agacaccacc agtaagctgg ttgtgacgcc actcggtagc
    17881 ctggcgttcc agtatgccga aggcattaaa ggttttaact cacagaaagg tctatttgac
    17941 gtggctatcg agggtgactc aacggctacc gcctttaaac tgacctcacg tcttatcacc
    18001 aacaccttaa cccagttgga tacctcaggt tctacactga atgtgggcgt ggattataac
    18061 ggcgcggcag tcgaaaaaac tggcgatacc gtgatgatcg ataccgccaa cggcgtactg
    18121 ggcggcaacc ttagcccgct ggctaacggt tacaatgcca gcaatcgtac caccgcacag
    18181 gatggtttca ctttctccat catcagcggc accaccaatg gtaccaccgc agtaaccgat
    18241 tacagcactc taccggaagg catctggagc ggcgacgtta gcgtacagtt cgacgcgacc
    18301 tggaccagtt aatctctctg atgtaccagc aggggtagcc cccccccctg ctttattcct
    18361 ggacggaatt gttatgaaaa agcaccttct gcttctcgct ctgctgttat ccggaatatc
    18421 tccggcccag gcgctggatg tcggcgatat atcatcgttt atgaacagtg acagcagcac
    18481 gctgagcaaa acgatcaaaa acagtaccga cagtggtcgc ctcatcaata tccgtctcga
    18541 acggctctct tcaccgcttg acgacgggca ggttatcgca atggacaagc cggatgagtt
    18601 gctactcact cccgccagct tgctgctacc cgcccaagcc agcgaagtga tccgcttctt
    18661 ctataaggga ccagcagatg aaaaagagcg ctactaccgc attgtctggt ttgatcaggc
    18721 cctcagtgat gcgcagcgcg ataatgccaa ccgcagcgct gtggccactg cttccgcccg
    18781 catcggcacc attctggtcg tcgcaccccg ccaggcaaac taccactttc agtacgccaa
    18841 cggctccctg acaaatacag gaaatgcgac gctgcggatc ctcgcttacg gcccctgcct
    18901 gaaagccgcc aatggtaagg agtgtaaaga gaattactac ctgatgccgg gcaagtcgcg
    18961 tcgttttacc cgcgtggaca cggcggataa caaaggacgg gttgcacttt ggcagggtga
    19021 taagttcatt cccgtgaaat agatagctgt gcagatggat aacgacaatg cctttacgac
    19081 ggttctcccc aggactgaaa gcccagtttg ccttcggcat ggtctttttg ttcgttcagc
    19141 ccgatgccag cgctgctgac ataagtgcgc agcaaatagg tggggtgatt attccgcagg
    19201 ccttcagtca ggcgctccag gacggcatga gcgtcccgct ttatattcat ctcgccggta
    19261 gccagggtcg ccaggacgat cagcgaatcg gcagcgcttt tatctggttg gatcatggac
    19321 agctacgcat ccggaaaata cagctggaag agagtgaaga taacgccagt gtcagcgaac
    19381 aaactcgaca gcagctgatg gctctggcga acgccccgtt caatgaggcc cttaccatcc
    19441 ccctgactga caacgcgcag ctggatctca gcttgcgcca actgctgctg cagctggtgg
    19501 tcaagcgcga agcgctgggc actgtactac gctcacgtag cgaagacatc gggcagtcca
    19561 gtgttaacac cctcagcagt aatctgagct ataacttcgg catctataac aaccagttgc
    19621 gtaacggcgg gagcaacaca tccagctatc tgtcgctgaa taacgttact gcactgcgcg
    19681 aacatcatgt ggtgctcgac ggctcgctgt acgggatcgg tagcggtcaa caggacagtg
    19741 aattatataa agcgatgtat gaacgcgatt ttgccggtca ccgatttgcc ggtggaatgc
    19801 tcgacacctg gaacttgcag tccttagggc cgatgaccgc catttcagca gggaagattt
    19861 acggcctttc ctggggaaac caggccagct ccaccatctt cgacagcagc cagtcagcca
    19921 cgccagtgat cgccttttta ccggcggcgg gcgaagtaca tctcacccgt gatgggcggc
    19981 tactaagcgt tcagaacttc actatgggca atcatgaagt ggatacccgg ggtctaccgt
    20041 acgggattta cgatgtggaa gttgaggtga tcgttaacgg tcgcgtgatc agcaaacgcc
    20101 cccagcgggt caataagctg tttagccggg ggcgcggcgt cggtgcacca ctggcgtggc
    20161 aggtatgggg cggtagcttt catatggatc gctggtcgga aaacgggaaa aagacgcgac
    20221 cagctaaaga gagttggcta gcaggtgcct cgacctccgg ctcattgagt acgcttagct
    20281 gggcggcaac gggatatgga tacgataatc aggcggtggg tgaaacccgt ctgacgctgc
    20341 cgcttggggg agcgatcaac gttaacctgc aaaatatgct ggccagtgac agctcatgga
    20401 gcaacatcgc cagcatcagc gccactctac cgggaggctt tagttcgctg tgggttaacc
    20461 aggaaaaaac ccgcattggc aatcaattgc gacgtagcga tgccgacaac cgtgcaatcg
    20521 gcggcacact caacctgaac tcactgtggt cgaagctggg cacattcagc atcagctaca
    20581 atgatgaccg ccgttacaac agccattatt acacggcaga ttactatcaa aatgtctaca
    20641 gcggtccctt tggttcgctt ggcctgcggg ccggtattca gcgctataac aacggcgaca
    20701 gcaacgccaa tacagggaaa tatatcgctc tcgatctctc gctaccactg ggcaactggt
    20761 ttagcgcagg gatgactcat caaaacggct acaccatggc aaacctgtca gcacgcaagc
    20821 agtttgatga agggaccatt cgcactgttg gtgccaatct gtcacgagcc atctccggcg
    20881 ataccggtga tgacaaaacc ctcagcggtg gggcgtatgc acagttcgac gctcgttacg
    20941 ccagcggaac gctgaacgtc aatagcgcgg cggacggcta cgtcaatacc aatttaaccg
    21001 ccaatggcag cgtcggctgg cagggtaaaa acattgctgc cagcgggcgg actgatggca
    21061 acgctggggt gatattcaac accgggctgg aggacgacgg tcagatcagc gccaaaatca
    21121 acgggcggat tttcccgctt aacggcaagc gtaactatct cccgctctct ccctatggaa
    21181 gatatgaggt ggagttacag aacagcaaaa actcactcga cagttacgat atcgtcagcg
    21241 gccgcaaaag tcatctgact ctctatccag gcaatgtcgc tgtcattgag ccagaggtga
    21301 agcagatggt taccgtctcc ggccgtatcc gtgcggaaga cggcacactg ctggctaacg
    21361 cacggattaa caaccatatc ggccgaaccc gaaccgatga aaacggcgag tttgtcatgg
    21421 atgtggacaa gaaatacccc actatcgatt ttcgctacag tggcaataaa acctgcgaag
    21481 tggcactgga actcaaccag gcgcgcggtg ccgtctgggt cggagatgtg gtctgcagcg
    21541 gcctctcatc gtgggcggcg gtgacgcaga caggagaaga gaatgagagt taacctactg
    21601 atagcgatga taatctttgc gctaatctgg cctgcaaccg cgctcagagc tgcagtgagc
    21661 aaaacaacct gggcggatgc accggcacgc gagtttgtgt ttgtcgaaaa caactcagac
    21721 gacaactttt tcgtcactcc tggcggggcg ctggatccgc gcctgaccgg tgccaaccgc
    21781 tggaccggtt taaaatacaa tggttcagga accatctatc agcaaagcct cggctacatt
    21841 gataacggtt acaacaccgg cctttatacc aactggaagt ttgatatgtg gctggaaaat
    21901 tcaccagttt catctccttt aactggcttg cgctgcatca actggtacgc tgggtgtaat
    21961 atgaccacca gtcttatcct gccgcaaacc accgacgcca gtggatttta tggcgcgacg
    22021 gtgaccagcg gcggcgcgaa gtggatgcac ggcatgttgt cagacgcgtt ttaccagtat
    22081 ctgcaacaaa tgcccgtcgg cagcagcttt acaatgacca tcaatgcctg ccagacctct
    22141 gtgaactatg acgccagcag cggcgcacgc tgtaaggatc aggcctccgg caactggtat
    22201 gttcgcaacg tcacccatac gaaagcagca aatctacggt tgataaatac ccactcgctg
    22261 gcggaagtat ttatcaacag cgacggagta ccgactctgg gcgaagggaa cgccgactgc
    22321 cggacgcaaa ccatcggcag ccgttcagga ttaagttgta agatggttaa ctataccctg
    22381 caaacaaacg gactcagcaa cacctcaatc catatattcc cggcgatcgc caactcgtcg
    22441 ttagcctcgg ccgtcggggc gtacgatatg cagttcagtc tgaatggcag ttcatggaaa
    22501 ccggtgagca atactgccta ttactacacc ttcaacgaga tgaagagcgc agactcgatc
    22561 tatgttttct tctcgagcaa cttctttaag cagatggtga acctcgggat cagcgatatc
    22621 aacaccaaag atctattcaa ctttcgcttt cagaacacca catcacagga gtctggctgg
    22681 tatgaatttt ctacctccaa cacgctgatt atcaaacccc gtgatttcag catcagtatt
    22741 atctccgatg aatatactca gacaccgtcg cgggagggat atgttggcag cggcgagtcg
    22801 gcactcgatt tcggctatat cgtaaccacc agcggtaaaa cagctgccga cgaagtgctg
    22861 atcaaggtga ccggacccgc gcaggtgatt ggcgggcgct cctattgtgt cttcagctcc
    22921 gatgacggta aggcgaaagt accgttcccg gcgacgcttt cctttattac ccgcaacgga
    22981 gctacaaaaa cctacgatgc cgggtgcgat gatagctggc gtgatatgac cgatgcgctg
    23041 tggctgacca caccgtggac tgatatctct ggcgaagtgg ggcagatgga taagaccaca
    23101 gtcaaatttt cgattccaat ggataacgcc atttcgctgc gtacggtaga tgataacggc
    23161 tggtttggcg aagtcagcgc ttcaggagaa attcatgttc aggcgacgtg gcgtaacatt
    23221 aactaaggcc ctgctgacag cggtctgtat gctggcgaca cctttgacac aggcgatttc
    23281 ggtcggcaat ctgacatttt cgctgccgtc cgagactgac tttgtcagca aacgtgtagt
    23341 gaataacaac aaaaacgcac ggatataccg tattgccatc agtgctattg atagcccggg
    23401 cagcagtgaa ttgcgcaccc gaccggtgga tggtgaactg cttttcgccc cccgccagct
    23461 agcgttgcag gctggtgaga gcgagtattt taaattttac tatcatgggc cacgggataa
    23521 ccgcgagcgc tactaccggg tctcatttcg cgaggtcccc actcgtaacc agacaagacg
    23581 tagcccaacc ggcggcgagg tcagcacgga gccggtggtg gtgatggata ccattctggt
    23641 agtacgacca cgtcaggttc agtttaaatg gtccttcgac aaggtgacag gaacggtaag
    23701 taacactggc aacacatggt ttaagctact gattaagcca gaatgtgatt cgaccgaaga
    23761 ggaaggcgat gcctggtatc tacgtccggg agacgtggtt catcagcctg agttacgtca
    23821 gccggggaat cattatctgg tctataacga caaattcatt aagattagcg attcctgtcc
    23881 ggctaagccc ccttcggcgg actaagactt atccatcggt cgagggaaga attccacctc
    23941 agagccccaa aaatcgttta aatgatgtgg aagcgatcgt caatatcacc tgtaacgatg
    24001 ggctttctca tatgcacacc atagtgttca ggagacacgg aaaggtatca ggcagcctgc
    24061 taacgagtgg tttaatcacg aattagtacg taaaatcggt aacggctgga aatcattcaa
    24121 tactcacact atcgaaagtt ccccagccaa ccgcggtacg ttcttacata cgatgtaccg
    24181 ctgttctctt tacgattttt agctgtactg gtgaattatg agcaatctga atccatgcat
    24241 gacgtgtggt gcctgttgtg catttttccg cgtctctttt tactgggccg aagccgacga
    24301 tgctggcggc actattcccg ccaggctcac tgaacaaata tccccttttc accgatgcat
    24361 gagcggtacc aatcagaaaa acccccgatg tattgccctt gcaggaaccc cgggcaaaaa
    24421 tgcctgctgc acgatatata aaaatcgatc gtccacatgc agagaatttg ccatgtctgg
    24481 tgagaacgga gtcgtcaatg aggcttgcaa tcgtgcaagg gctaaatacg ggctgacacc
    24541 gttataaaca tacaataatt aattgcactg ccccgccagc gataatagcg gggcttcgtt
    24601 tttcaggggt aacaaaaccc gat
//
LOCUS       DAZUDJ010000071        23869 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.071, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000071 DAZUDJ010000000
VERSION     DAZUDJ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23869
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.071"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            291..2963
                     /gene="rcsD"
                     /locus_tag="ACHY1N_003862"
     CDS             291..2963
                     /gene="rcsD"
                     /locus_tag="ACHY1N_003862"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0009927 - histidine phosphotransfer kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HFS4046076.1"
                     /translation="MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIQKRVDTWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLVLIST
                     LPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNMRRLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDATATGDNDNEKEGTDSVSIHFNS
                     TKIEISSALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFS
                     SRSTESLPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHL
                     NLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRMTFMKNIGDALKEPAQSLAESAAKLNAPESKQLANQADVLVRLVDE
                     IQLANMLADDSWKSETVLFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGD
                     RDALRRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLH
                     FPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPE
                     VEEEEERLLDDVCVMVDVTSAEIRNIVTRQLENWGATCITPDERLISQDYDIFLTDNP
                     SNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLG
                     GDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPG
                     KQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL"
     gene            2980..3630
                     /gene="rcsB"
                     /locus_tag="ACHY1N_003863"
     CDS             2980..3630
                     /gene="rcsB"
                     /locus_tag="ACHY1N_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor RcsB"
                     /protein_id="HFS4046077.1"
                     /translation="MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD"
     gene            complement(3830..6679)
                     /gene="rcsC"
                     /locus_tag="ACHY1N_003864"
     CDS             complement(3830..6679)
                     /gene="rcsC"
                     /locus_tag="ACHY1N_003864"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0018106 - peptidyl-histidine
                     phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HFS4046078.1"
                     /translation="MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQADVPAF
                     EPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     RDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANR
                     LQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKGDPRWMQERSW
                     FGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLA
                     RMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQE
                     PTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARI
                     YLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDVIKQTLTVYAERVRKSRES"
     gene            complement(6954..7730)
                     /gene="yfaP"
                     /locus_tag="ACHY1N_003865"
     CDS             complement(6954..7730)
                     /gene="yfaP"
                     /locus_tag="ACHY1N_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaP family protein"
                     /protein_id="HFS4046079.1"
                     /translation="MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASF
                     SQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRVESDGSF
                     ARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHV
                     VTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETE
                     LTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW"
     gene            complement(7735..9384)
                     /gene="yfaQ"
                     /locus_tag="ACHY1N_003866"
     CDS             complement(7735..9384)
                     /gene="yfaQ"
                     /locus_tag="ACHY1N_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaQ family protein"
                     /protein_id="HFS4046080.1"
                     /translation="MNWRRIVWLLALVTLPTLAEETPLQLVLRGAQHDQLYQLSSSGV
                     TKVSALPDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRD
                     TALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLA
                     TLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTD
                     GTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKST
                     TAVKPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDRE
                     AKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTGARTMTAWT
                     QDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRS
                     TCQLLPKAKAWLAKKMPQWRRILQGETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRN
                     FFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD"
     gene            complement(9385..13899)
                     /locus_tag="ACHY1N_003867"
     CDS             complement(9385..13899)
                     /locus_tag="ACHY1N_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004866 - endopeptidase inhibitor activity
                     [Evidence IEA];
                     GO_process: GO:0010951 - negative regulation of
                     endopeptidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin"
                     /protein_id="HFS4046081.1"
                     /translation="MGTGLANADDSLPSSNYAPPAGGTFFLLADSSFSSSEEAKVRLE
                     APGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWL
                     WDNWYGKSRRVMQRTFSSQSRQNVTQALPELHLGNAIIKPSRYVQNNQFSPLKKYPLV
                     EQFRYPLWQAKPVEPQQGVKLEGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYR
                     ATTVVFVSDTVALSKVSGNELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGT
                     LQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKV
                     MGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVDVTLDARNGGQGSFRLPENAVAGG
                     YELRLAYRNQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVK
                     NARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNLPAADKPSRYLL
                     TVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVT
                     YEWLRLEDRTSHSGELPSGGKSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGST
                     AHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTL
                     QRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTH
                     YQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRT
                     SSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKA
                     YFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAG
                     LFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLAQNIQQSGLLSAELQQNGQV
                     QDSISTKLSFVDNSWPVEQQKNVMLGGGENALMLPEQASNIRLQSSETPQEIFRNNLD
                     ALVDGPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGAR
                     FTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNMPLLHRA
                     LVLAWAQEMNLPCKTLLKGLDEAIARRGTKDEDFSEEDIRDINDSLILDTPESPLADA
                     VANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQTAAIL
                     SGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEDWRWVGQGVP
                     DILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSN
                     EIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQL
                     LEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAA
                     GSEWTGMQVK"
     gene            complement(13923..14546)
                     /gene="yfaT"
                     /locus_tag="ACHY1N_003868"
     CDS             complement(13923..14546)
                     /gene="yfaT"
                     /locus_tag="ACHY1N_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1175 domain-containing protein"
                     /protein_id="HFS4046082.1"
                     /translation="MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQ
                     GPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGFSSQYLPPEMTLTPGQRQLAQNW
                     NQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYH
                     TGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR"
     gene            complement(14543..16231)
                     /gene="yfaA"
                     /locus_tag="ACHY1N_003869"
     CDS             complement(14543..16231)
                     /gene="yfaA"
                     /locus_tag="ACHY1N_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416733.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2138 domain-containing protein"
                     /protein_id="HFS4046083.1"
                     /translation="MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSP
                     LVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIE
                     GSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPL
                     LFAATSDSQLSKTEISSIKINSETVPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFK
                     DDQQDTEATAIAGDLLSGKKRWQASFGLEERAAEKTPVRQRIVVSARLLGFGYQRLMP
                     SFAGVRFEMGNDGWHSFVALNDESASVDTSFDFTPVWNSMPAGASFCVVVPYSHGIAE
                     EMLSHISQENDKLNGALDGAAGLCWYADSKLQTPLFVGQFDGTAEQAQLPGKLFTQNI
                     GAHESKAPEGVLPISQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLA
                     MQNKTLLFSLDDTLVNNALQTLNKNRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLT
                     SLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL"
     gene            complement(16380..19007)
                     /gene="gyrA"
                     /locus_tag="ACHY1N_003870"
     CDS             complement(16380..19007)
                     /gene="gyrA"
                     /locus_tag="ACHY1N_003870"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009330 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) complex [Evidence
                     IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HFS4046084.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDP
                     IIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELEL
                     VREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLP
                     LEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDEL
                     IGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRG
                     DGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAA
                     EGDDEIAPEVDVDDEPEEE"
     gene            19154..19876
                     /gene="ubiG"
                     /locus_tag="ACHY1N_003871"
     CDS             19154..19876
                     /gene="ubiG"
                     /locus_tag="ACHY1N_003871"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="HFS4046085.1"
                     /translation="MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLR
                     LGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNP
                     ITNTFKLGPGVDVNYMLHTQNK"
     gene            complement(20004..23738)
                     /gene="yfaL"
                     /locus_tag="ACHY1N_003872"
     CDS             complement(20004..23738)
                     /gene="yfaL"
                     /locus_tag="ACHY1N_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA-I family autotransporter adhesin YfaL/EhaC"
                     /protein_id="HFS4046086.1"
                     /translation="MRIIFLRKEYLSLLPSMIASLFSANGFAAAIDLCQGYDIKASCH
                     ASRQSLSGITQDWSVADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFAN
                     NTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGDGGAIYSSGTNDTGAVDLRVTNA
                     MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSK
                     HPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSA
                     AGYGDGPSTAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSG
                     DLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQN
                     QAELNVGSTQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSY
                     VLSGAQSMALTGDIVVDDGAVLSLEGDAADLAALQDDPQSIVLNGGVLDLSDFSTWQS
                     GTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANN
                     NSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITANVDTRSTTTEHG
                     RDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTFTKTGAGTLELTASGTTQSA
                     VRVEEGTLKGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSGTIDISDGTVLR
                     LTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLADVTVNGDLTNT
                     SGAVSLKNGVAGDTLTVNGDYTGGGTLLFDSELNGDDSVSDQLVMNGNTAGNTTVVVN
                     SITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLR
                     SQEVTPPSPPDPDPDPTPDPDPTPDPIPAYQPVLNAKVGGYLNNLRAANQAFMMERRD
                     HAGGNGQTLNLRVIGGRYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGAVG
                     GYSDNQGESRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWFNNDV
                     SEQDDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANHARVS
                     QSQGDDIQTRLGLHSEWRTAVGVTPTLDLNYYHDPHATEIEEDGSTISDDAVKRRGEI
                     KVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW"
BASE COUNT         5722 a         6514 c         5834 g         5799 t
ORIGIN      
        1 attattctgt gctaccacag aaaaactata acgcttgtta actatttcac aaataattaa
       61 catcagcata atttccagca atctttgttt atttgcaatt atttttgttg ggctttttgt
      121 aggttatttg tacagcaaaa tggcgcttgt acatctattt cccccaatgc aggatgataa
      181 atatcacggg agaatagaga atcatcaatc aggtaagagt ctggaatttc acactgtacc
      241 ctttatactg ccctatcact tcgcgaagtt ttaacaggtc ataaacacga atgcgtcaga
      301 aagagacaac ggccacgacc cgcttttcac tcctaccggg gagcattacc cgcttctttt
      361 tactgttgat cattgtgtta ctggtgacga tgggggtaat ggtacaaagc gccgttaacg
      421 cctggctgaa agataaaagt taccagattg tcgacattac ccacgctatc caaaagcgcg
      481 tcgatacctg gcgttacgtg acctggcaga tctacgacaa cattgccgcg acgacctccc
      541 cctcctccgg cgaaggttta caagagacgc gcctgaaaca ggatgtctac tatctggaaa
      601 aaccgcgccg caaaacggaa gcgttaatct ttggctctca cgacaactca acgcttgaga
      661 tgactcaacg gatgtccacc tatctggaca cattgtgggg cgcagaaaat gtaccgtggt
      721 cgatgtatta cctgaatggt caggataaca gtctggtgct gatctcaacc ctgcccctca
      781 aagatctcac ctccggattt aaagaatcga ccgtcagtga cattgttgat tcacgtcgtg
      841 cagaaatgtt gcaacaggcc aacgccctcg atgaacgcga aagtttttct aacatgcgcc
      901 gcctggcctg gcagaacggt cattacttta ccttgcgtac cacgttcaac cagccgggac
      961 atctggcaac ggtcgtggct tttgatctgc cgattaatga tttgatccca ccgggtatgc
     1021 cgctggacag tttccgcctt gagccagacg cgacggcaac gggagacaat gataatgaga
     1081 aagaagggac ggatagcgtc agtatccact ttaacagtac gaagattgaa atctcctcgg
     1141 cactcaactc taccgatatg cgcctggtct ggcaggttcc ttatggcacc ttattgctgg
     1201 atacgttgca aaacattctg ctgccactgc tgctgaacat cggtttgctg gcgctggcgt
     1261 tatttggcta taccacattc cgccatttct ccagccgcag tacagaaagt ctacccagca
     1321 cggcggtcaa taacgaattg cgcattttac gggcaattaa tgaagagata gtctcactgc
     1381 tgccgctcgg cctgctggtt cacgatcagg aatcgaaccg cactgtcata agtaacaaaa
     1441 ttgccgatca tttgctgccg catttgaatc tgcaaaacat caccaccatg gcggaacagc
     1501 atcaggggat tattcaggcg acgatcaata acgagctgta tgagatccgc atgttccgca
     1561 gccaggtcgc gccgcgcaca caaattttca ttattcgcga tcaggatcgc gaagtgctgg
     1621 taaacaagaa actcaagcag gcgcagcgtc tgtatgagaa aaaccagcag gggcggatga
     1681 cctttatgaa aaacattggc gatgcgctga aagaacccgc acagtccctg gcggagagcg
     1741 cggctaaact caacgccccg gaaagcaaac aactggcgaa tcaggcagat gtgctggtgc
     1801 ggctggttga tgaaatacag ttagcgaaca tgcttgcgga tgatagctgg aaaagtgaga
     1861 cggtgctgtt ctccgtgcag gatttaattg atgaagttgt gccttcagtg ttgcctgcca
     1921 tcaagcgtaa aggtctgcaa ctgctgatta acaatcatct gaaagcacac gatatgcgcc
     1981 gcggcgatcg cgatgcctta cgacgtattt tgctgctact gatgcaatat gccgtgacct
     2041 caacgcaatt gggaaaaatc acccttgagg ttgatcagga tgagtcctcc gaagaccgcc
     2101 tgacgttccg cattctggac acgggagaag gcgtaagtat tcatgaaatg gataatttgc
     2161 acttcccgtt tatcaaccag acccaaaacg atcgctatgg caaggcggac ccgctggcat
     2221 tctggctgag cgatcaactg gcacgtaaac tgggcggtca tttaaacatc aaaacgcggg
     2281 atgggcttgg tacacgctac tctgtgcata tcaaaatgct cgcagctgac ccggaagttg
     2341 aagaggaaga agagcgttta ctggatgatg tctgcgtaat ggtggatgtt acttcggcag
     2401 aaattcggaa tattgtcact cgccagttag aaaattgggg tgcaacctgt atcacacccg
     2461 atgaaagatt aattagtcaa gattatgata tctttttaac ggataatccg tctaatctta
     2521 ctgcctctgg cttgctttta agcgatgatg agtctggcgt acgggaaatt gggcctggtc
     2581 aattgtgcgt caacttcaat atgagcaacg ctatgcagga agcggtctta caattaattg
     2641 aagtgcaact ggcgcaggaa gaggtgacag aatcgcctct gggcggagat gaaaatgcgc
     2701 aactccatgc cagcggctat tatgcgctct ttgtagacac agtaccggat gatgttaaga
     2761 ggctgtatac tgaagcagca accagtgact ttgctgcgtt agcccaaacg gctcatcgtc
     2821 ttaaaggcgt atttgccatg ctaaatctgg tacccggcaa gcagttatgt gaaacgctgg
     2881 aacatctgat tcgtgagaag gatgttccag gaatagaaaa atacatcagc gacattgaca
     2941 gttatgtcaa gagcttgctg tagcaaggta gcctattaca tgaacaatat gaacgtaatt
     3001 attgccgatg accatccgat agtcttgttc ggtattcgca aatcacttga gcaaattgag
     3061 tgggtgaatg ttgtcggcga atttgaagac tctacagcac tgatcaacaa cctgccgaaa
     3121 ctggatgcgc atgtgttgat taccgatctc tccatgcctg gcgataagta cggcgatggc
     3181 attaccttaa tcaagtacat caagcgccat ttcccaagcc tgtcgatcat tgttctgacc
     3241 atgaacaaca acccggcgat tcttagtgcg gtattggatc tggatatcga agggatcgtg
     3301 ctgaaacaag gtgcaccgac cgatctgccg aaagctctcg ccgcgctgca gaaagggaag
     3361 aaatttaccc cggaaagcgt ttctcgcctg ttggaaaaaa tcagtgctgg tggttacggt
     3421 gacaagcgtc tctcgccaaa agagagtgaa gttctgcgcc tgtttgcgga aggcttcctg
     3481 gtgaccgaga tcgctaaaaa gctgaaccgc agtattaaaa ccatcagtag ccagaagaaa
     3541 tctgcgatga tgaagctggg tgtcgagaac gatatcgccc tgctgaatta tctctcttct
     3601 gtgaccttaa gtccggcaga taaagactaa tcatctgtag gccagataag acgcgttagt
     3661 gtcttatctg gcatttgcac cgattgccgg atgcagcgta aacgccttat ccggcctacg
     3721 attcccatta tttcaacaga ttacattaaa gtaggccaga taagacgcgt cagcgtcgca
     3781 tctggcattt gcactgaatg ccagatgcgg cataaacacc ttatccgtcc tacgattccc
     3841 gcgatttcct gaccctctcg gcatataccg tcagcgtctg ttttatcaca tccagcgtta
     3901 ccggcttcga caggcagctg tccataccgg actccagaca ccgctgcttc tcttcagcca
     3961 acgcattagc agttactccg attaccggca acgtcagtcc caactgacga atgcgttgcg
     4021 tcaagcggta accatccata tttggcatgt tgacgtcgct aagcacgata tcaatatgat
     4081 tcttgctaag tacattaagc gcatcgacac catcattcgc ggttttacat tgatagccca
     4141 acgatcccaa ctgatctgcc agcagacgtc ggttaatcgg atgatcatcc acgaccagaa
     4201 tcatcatatc gtcattatcg ctgaccgctt tgtccgtcga cggcagagcg ttagcaggat
     4261 cgtcgctctc catctcgatc aaataaatac gcgccaacaa tgccggtagc tcatgcgggg
     4321 cagccacact gtgtacccac tcccctggcg ctttctccag cggaatacca atatggcgac
     4381 gacagaaggt cactaccgct ctaccctgcc attttttact cactacctcg tcagtaatta
     4441 acacatcttc gggagtcggt tcctgccctt cgtatgttgt aacgacgatg ccgctgcgct
     4501 gcaaactggt ttccaggaac tgacagagcg acgcattgcg gaccgccagc cagcagcgtt
     4561 taccactcaa cccttccacg ccttttttct gcgggtactg agcgccgtac aacggaatac
     4621 gcacggtaaa ctggctgccc attcccggtt ctgaatctac cgagatatcg ccgtccatca
     4681 tgctgatcag tttttcacaa atcgccagac ccagaccggt cccctggaag tttcgctgta
     4741 cgcccgttcc gacctggaag aagggatcaa acaagcgcac cacttctttc gccggaatcc
     4801 ccacgccggt atcgcgaaca cggatagaga gataatcgcc atcagcgcgg acatgcaaaa
     4861 ctatacagcc ggtatcggtg aattttatgg cgttactcaa caggttggag atgacctgct
     4921 gtaaacgcat cgggtcgcca tttaaggcca ctggcacatc cggttcaata aagcagtaca
     4981 agcctaactg cttgcgtacc accagcggta aatagttggc ggtgatgtgg ttcatcactt
     5041 cacgcggtga aaactcacgc ggttcgatct tcaactgttc cgattcaatc ttcgagaaat
     5101 cgagaatatc gctgataatt ttcaacaaca ggctggaaga gttgttcatt gccgtcacca
     5161 gccgatcgac gcctttcggt aactctttgg tttgcaacag atccaggtta ccgataatgc
     5221 catacagcgg cgttcgcagc tcatgactga cggtggcaag gaacatcgat tttgactggc
     5281 tcgcctgttc cgctgcttgt gccatctcct gcaacgactc ttccatcttc acgcgcgaag
     5341 aaacatccac cagcacacaa atggccacgt tttcattacg atagcgcgaa tggacgaagc
     5401 tgatttgcag attggtattg ttgctggtca ggacatcaac aaaattgacc tgctgcccac
     5461 agataatttg cgtcagtcgt tggcggtcct catgcgtaag catattgaga taggtatgcg
     5521 ccagttcgtt acttaaaata ttgacgccat cagcggtacg caaaatacag atacccactg
     5581 gcgcggaggc gacaatcttg cgattgaact gctcatgttc ttccagtcgc agggcgtcgc
     5641 tttccgccgg aatgaaaata cgtcgctcgt acatccgcgc gagagtaaac aatgcagctc
     5701 cggcaagcac attcagcaaa attgcgttaa ggatcaacat gcgaatgcgt tccagcacct
     5761 tatcaaccgg caccgaatac acgatgctta gcgatgaggg tggcagattt ttcttcagca
     5821 ccagctcccg gaacccttcc gtatagccaa accaggagcg ttcctgcatc cagcgaggat
     5881 cgcccttaat tttactttct ggtccggtaa gcgaaatcag ggtatgacca ttttcatcaa
     5941 gaatggtaac ccccatcggc aacgtacccg gtaagaaaaa gttctccatc cggatggtct
     6001 gctcgacacc caaaagcgcc tgcaaccggt tcgccagata aactggcgtc aacgcgtaaa
     6061 aatacccgac gccagggcgc ggaccttcgc tgatccagta gaggttactg ccgctatcat
     6121 cttgtggtgc atttcgatat ttattgatgc gttcatgcaa agctttcaac gcggtatcgc
     6181 gttccactgg catatcacgc agaccgaaat tggccatgca gaggttatca ctgccgatta
     6241 aaaatacccg gttgagatcg taagccgcag aaaaattatc gcgccagtag cgcataaacc
     6301 acgccaatga ctccagagaa cctcgccagg tgttactcat tgcggaacaa tcggagtcgg
     6361 caaacagcgg ttcaaacgca ggcacatccg cctgcgtttc tcgtccacgc ggggaaagca
     6421 caccgttttc tgccgataag cgattttcgg cgatgtactt cagctctttc atcacatcag
     6481 aggtgcgttg aataaagcgc tgagcctgat cggaactcag attaaattcc tgacgaattt
     6541 ccgattctcg ctgatgtaac gcattaacga tgtaaaaaac ggatgaaaaa gcaatcaaca
     6601 gccagagcac taacgccaat gctctgaaca tgtagcgcga ggctttcagg gttgtacgaa
     6661 aagaagcaag gtatttcaaa ggggcgaagc tccgcctcag gtgaccgatg gagtgtggtt
     6721 aaggtagcgg taaaagcgtg ttaccgcaat gttctgtcac cattgcaata atgcgtatcg
     6781 cttagaaacc attgccttaa ccaggaaagc cggagtagat ggacagttct cagtacgaaa
     6841 aataagaaat gaccaatctg ccgacgcttg ttaatggtta tatcctggcg tcggcagatc
     6901 gcccagcagt cttatctgaa aaaagagaga gccaggttgt gtgaagggat ggatcaccag
     6961 tcaaaacttt tcaccagcgt cagctcgcca gcattacgca tcggtacaat aaatgtttcc
     7021 tgtttctcat tgaccgatcc ttcatcggtg atcagcgtca gttgggcggt cgtcaattcc
     7081 gtttcgctgc gcccaccata gtagttgata tacacctgat agcgcccgtg aactggtgct
     7141 ggcatggcga aaatctcggg tccgtacccc gtcgtgacat ccatatccag tgcaccactg
     7201 tttttcagca cggtgttacc gtaccaggcg tgttcgccat cgggcgtgac aacatggaga
     7261 tcgagatcgg tattgtccgt atcccacgag agaaccagcc gtaaacgtgc acgaatcgtt
     7321 cctgtacccg gcgttgagta aaactgcatt ttttgtcggc tttgcccatc cgggctgatg
     7381 acctgcacgc tgttgctgcc ttcagtgaaa atataagggc gtgcaaatga accatcggat
     7441 tcaactctct gcggcatact ggcaccgttg accaccagcc ggccctgctg aactttaccc
     7501 gccgcagcat aattctttat tttgccgcgg atctgcgctg agatattttg atcatctgcc
     7561 atgttgacgg acgacgccgg gtaattgatc gattgtgaaa aactggcatc ttcgccctct
     7621 gccggatgcc agccagagag cggtgcgtca atctcgactt cctgcacacc ttcactgtga
     7681 gcgacaggcg aaagtgccac cagtaacaac ggaagaaaaa tctttcgcat agcattagtc
     7741 cattaataat tgtcgggtca gcgtttcgat atagttctca tcaagcccgg tgggataacc
     7801 atcaaaggcc aggtgcagat actcatgggt taaatccagc cgatcctgaa gcgtaaagaa
     7861 gttacgaata aacagccgtt tctgctgccg atcggtatag gggaaacctg agactaaacg
     7921 acagaccgca aacacgtctg gttcgttgta ccccgtctcg ccttgtaata tacgccgcca
     7981 ctgcggcatt tttttcgcca gccaggcttt cgctttgggt aataactggc aggttgagcg
     8041 tggagctccc cagcggctaa ggctgttgtc gggataagca aacgcgagta tctggtcgta
     8101 acgctccccc tgccccgcct gggccgtggc ttgccgccag gaaagtgtcc cttcggtagc
     8161 gcgactgcca tgataatgaa ccggatcgcc tgcatagatg agatcctgcg tccaggcggt
     8221 catcgttcgc gcccccgtgg tcgctggcga agcagaaaca cgctgcgtgg cgctgctgtc
     8281 ggggatggtc aggcaatcgc cttcccgatt ggcgttttgc tgtaaaaaag tgcgaatcgc
     8341 cacggtcatg gctttcgctg cctcaggggg cgtacttttc gcctcgcgat ccagaactct
     8401 ggcaacgtac tcttcacgat cgagatgcga ctgcaatttc agtttgccct tttcgctcag
     8461 taaggtcgtc tcaccgtggc tgacaaacgt aatgtggtta ccattagtaa acgtcacacg
     8521 atagcgccca ttaagtacgc cgggttttac tgccgtcgta ctcttttccg ctgtgatttt
     8581 cttcagcgga tagcgggcaa acagctccac ctctacacat tgcccactgg caacctgcgt
     8641 cggcactggc aaaacccgat taagcaccgt cgcataacgg gttagtaccg ttttgctggt
     8701 gccactgcca gtaacccaca gcggtgtacc atcggttaac cagccagcaa aaccaccctg
     8761 gcggatttcc tgtttatcat cggcaaacca gctccaggtt ttcacccgta cccgactacc
     8821 gagcatggat gcgacaccga ttttcgcctc gtccagcacc acatccagta agacttcctg
     8881 agctttgttt tgcgcaggta acgtcgctaa tgaatcgagc agcgatttaa ccgttaccga
     8941 ggtttctggc ttcagcgttg taagagacgc taaccacgca ggtgcctgac gctgttgcca
     9001 gtattgcccc cacacatctg cgccaatatg caaccgctgc ggcgcaaaat agagcccaca
     9061 ggaacgtacc agcgcggtat cgcgcgttat gctctcccca gcctgacaac aataaacctc
     9121 ttccggggag tttccgcgac actggtaggg ctgctccggt tgatgggtat cctccagcca
     9181 ggcgtaaaca tacagtttcc acaaactccc taacggcgtg gtgagcgagt caggtaatgc
     9241 tgagactttg gtcacgcctg atgacgacag ctgatacagt tgatcgtgct gcgcaccgcg
     9301 cagcaccagt tgtaacggcg tctcctccgc aagcgttggc agagtaacca acgccaatag
     9361 ccagacgatt ctgcgccagt tcacttattt cacctgcatc ccggtccatt cactccctgc
     9421 cgcaacactt tgctgcgcag gtgcatagga acgcacataa cgagcaggag gcagaacgaa
     9481 ttgccctttt tgcgagaagc gcagcaaatg gcggaaagtg accgttcccg tcagttcttt
     9541 caccggcacc atataggcca gttcgcccat ttcattacgc gctttttcca gcaattgccc
     9601 ctgctgtttc gcggcgttgg gtttattgac tgaaatgccc catgttgtgc gctcaacgtc
     9661 ggctcccggc gggagcggta cttccacctg accatagcgc agaactgcat cctgctcgct
     9721 ggtaagcgta atttcatcga gatacagcgc atcgctgtca atctcattgc tggtcaccgg
     9781 ctgcagagta aagctcatct cttcttcacc ggggataagc cgatacaact ggcgttcaac
     9841 ggtcaccgga atgttacttt gttgagccgt ttttgccggt tcacgccagc ggacctgcac
     9901 attttgcggc gataattcgt caccaaaaga gagaatgtcc ggcacaccct gaccaaccca
     9961 acgccagtct tcgccccctc cagttaactt atgtttagcc catgcgcccg caggcgcagg
    10021 caaaacaact ggaggcattg tcgccatata tttcgccagc cagttcatgg ccagcgcgcg
    10081 ctcaatagtg gattgctcag cggtcaaacc acttaaaata gcggccgtct gggtagcgtc
    10141 accaccgcta ttgagcagca caaccgtgtg cgccagcggc tgattgctgt ttgccgcttt
    10201 atcccacgca tattgctgaa cctgtggcat caccgtggac ttcaactgcg cttttttcag
    10261 caacgtcatg gttaagacgt ttgccaccgc atctgccagt ggagattccg gtgtatcgag
    10321 gatcaggctg tcattgatat cgcggatgtc ttcctcagag aaatcttcat ctttagttcc
    10381 gcgccgggcg atagcttcat ccaacccttt caacaacgtt ttgcacggca gattcatctc
    10441 ctgtgcccac gccagcacca gcgcccgatg caataacggc atgttatccg cctgctcggc
    10501 ataactgtcg agcatatgct gccagtattc cggttgttgc gttacgccga gcgcctggct
    10561 ggcctgccag tcggcgtacc atgcccatgc cgtaaggaag gcgtcaccat tgccatcttc
    10621 accccaccag gtaaagcgcg ctccgggccc cgccagttgc atcagccgca gacggttatc
    10681 ctgaatcatc tgacgaatgt cgttagcggc ggcactttga tgatcggcaa gcgaacgcca
    10741 ggcgagactg agcgggatca gacggctacc ggtgttgatc acgccacccc atggtccatc
    10801 gactaacgca tcaagattgt tgcggaaaat ctcctgcggc gtttcgctac tttgtagccg
    10861 gatattgcta gcctgctcgg gcaacatcag cgcgttctcg ccaccgccga gcatgacatt
    10921 tttctgctgt tcaacgggcc agctgttatc cacaaaagac agttttgtgc taatgctgtc
    10981 ctgcacttgc ccattttgtt gcagttctgc gcttaacaag ccagattgct gaatgttctg
    11041 cgccagcgaa atataattcg cccctttgtg cagcgtcagc gtctggcgca tctcagcgcc
    11101 tgcaaattta gtcaccagcg ccaccggttc gttatcctgc tgactgaaga taaacagtcc
    11161 tgccgccggt ttgtcgccca cgcgatacac cgttggcata ctccacttca tgtagagatt
    11221 tttttccgaa cgcagataag cacgcccctg cccgaccagc ccgtcgccgt tcatcccacg
    11281 cgcggtgata cgccagcggg ttaacgaatc aggcatcagg aacgtgaaat acgctttgcc
    11341 ttgtttatcg gttgtgagtg acggcatcca tgccgcggta tccacctctt cacgccgtgg
    11401 acgttcaagc atttttactc gccgctcgct gcggttagtt gcgccaggcg caaccggctc
    11461 gctggagagc gcctggtcgt agctgataaa cgacagactg gagctggtac gcacattgtt
    11521 acgccccagc ggatagaaaa atttgccgat attcggcgcg atttctggtt gcagcgcgta
    11581 gatcatttca tcgaccacgc ctaccgttag ctgcgcagaa acaggtttac ctttcagcga
    11641 cgaggttaat tcgacattga ccagttcacc aggctggtaa tgggttttgt ccgttttcac
    11701 ccggatatca agctgaggaa cggcaacttt gatcccggcg ttctgaaaac tgtactgacc
    11761 attacgggta tacagcaccg aaaaagtgat gttaggcgca aaggaattgc tcactggaac
    11821 ccgggcttca tactgggtat cgtttaaacg ttgtaacgtc agccagtttg ccggatgcga
    11881 aagcagcgac tgctgttcca cgcgatcgcg ttccagcgtc aataatgctt catcaattgg
    11941 ctccggaaag gtaatcagca tcttcgcagt ttcgcctggc tggtacagcg ttttatccgc
    12001 cacgatatct accgtaccag tatgcgccgt gctgccctta ccgctgacgg catgacttaa
    12061 cccagcgaga attaagccgt ctttatcgcg taatgtcaga ttgtagttgc caggtttagc
    12121 gaaattgacg gtaaaggatt tgccgcctga cggtagctct ccgctatggc tcgtgcggtc
    12181 ttcgagacgc aaccattcat acgtaacagg aacctgtttt gaagattcca gcgcggcata
    12241 acggaacaca accgactcgc cgctattact gtattgtgcg gcagtactta atgagtaatg
    12301 cgccagaccg cgttcaatga ggatctcttt ggtggtggtg acacgatacg ccgcgccgtc
    12361 actggcggag acggttaaca aataacggct cggtttatcg gcggcgggga gatttaacgc
    12421 cacatgaccg ctggcgtcgg acaccgtttc gctgccttcc agcgacacgg ggaaacgtcc
    12481 ggcataacgc aaatcgttac cgaccattga taattgctga gcgcgcaaac ttaactgcac
    12541 gcgggcattt tttaccggct cgccatccgg gtagagcagt tgcagtttgc cgctgaccgc
    12601 ttcgccagtt ttgaactctt ttttgtcgag agctaaacca atctcgaaat gtggcttgat
    12661 gtagtttgcc acgcgaaaac tgctgctata gacctgattg cggtaagcaa gacgtaactc
    12721 ataacctccg gcaacggcat tttctggcag gcggaaactt ccctgcccgc cattgcgcgc
    12781 atccagcgtg acatcgacgg tttgcaacag actgccgtta gcgtccagca ccgaaagctt
    12841 cgccggggcg ctgacgatgg gggatgaatg caacggatcg tggaactcgc ggcccatcac
    12901 tttaacatcg acacgatcgc ctgcgcgata tagcgggcga tcggtaaaaa tatacaagcg
    12961 ggtgttgtag atttcgcttt cgtagaagaa gttctcggag acaaaaacac cgccttcagc
    13021 atccttaccc agaatgtatg aacgttctgg cgatatatgt tgtaactgca aggtaccgct
    13081 gtcatcggtc acaccgcggg tcatcacgcc aagaccgtca gtccacaaga tctctgagcc
    13141 gggcttcgct tcaccctgtt ttttacccgc ggtccacacc agaagctcgt tgcctgacac
    13201 tttgctaagc gccacggtat cggaaacaaa caccaccgtc gtcgcccgat acccaccaac
    13261 catcgcctcg acgaggtaca gtcccggctc ttgttggccg agaggaatat aaatgttacc
    13321 cggctgcggc gagatgaaat tgctggatgc gccttccagt tttacccctt gctgcggctc
    13381 gaccggttta gcctgccata gtggataacg gaactgttcc accaagggat attttttcag
    13441 cggggaaaac tggttgttct gtacataacg ggaaggttta ataatggcat tgccgagatg
    13501 taattcgggt aatgcctgag tcacattctg ccgtgactga gaagagaaag tacgctgcat
    13561 tacgcggcga gatttgccgt accagttatc ccacagccag gtcagcgtat tgttcagccc
    13621 gtcgcccaga tattgcggtt gcaccacaat gcgatgcagg tttttctgct ggcgcaaaaa
    13681 tgccatcggg tcaggaatac gatacaggcg aacgtccacg ccgccgtact cttccatctg
    13741 atagcgccga taatcacgcc ccggcgcttc cagtcgcact ttcgcctctt cactgctgct
    13801 aaaactgctg tcagcaagca aaaagaatgt tcccccggcg ggcggcgcat agttactgga
    13861 aggaagcgaa tcatcagcat tagcaagccc tgttcccaca agagacaggg acaagcacgc
    13921 tgctatcgcg ccagaaaatt taaacgataa atgccaatga aattgggatt ggaatcgttg
    13981 ggtatccatc gggtgtcctt ccatgtcata agttgttgca gactgactgc gcgcattccg
    14041 ttgtcagttt tcgtggcgct tccggtgtgg tagatgacgt aacgccccat ccagaccatt
    14101 aagtgctggg catcgccctg atcgaaaaaa atcatatcgc caggcagcgc ctggtttatg
    14161 tcctggccaa taaactggct gttgtactga atcaaattaa tcgcggtcac gtaggggccg
    14221 gttttcccgt tcccctgatt ccagttttgc gccagttgac gctgtccagg tgttagcgtc
    14281 atctctggcg gcaaatactg gctagagaaa ccgttacttt ttagccattt actatcgtga
    14341 actttcagcg tctcgttcgc cgcaaatcgc accaggcccg cacaatcctg ctgataccag
    14401 cgtggacttg gcccctggcg gagctgttct tgtgcaatgc gtacaaacca ggcgcgaaac
    14461 agcccggatt gttcgacatt cagcatttcg ctatgggcaa caacacaaca cagccagcaa
    14521 atcagcgcca gcagcccgtg cctcatagcg gctgccaggt tatgggtagc cactgccagg
    14581 cggcaccggg ttccatctgg gccagcttca tgacataacg cggttgttga gataaagcgt
    14641 ccagcttcgg cattaataaa gtttgtgcgg cgttataaaa aaccggttcg agattcttcg
    14701 gcagactggt caacgtttcg ttacgcagca gtttcgccac gccttgtgga ttgatataga
    14761 gcggaacgat gccatcagtg ggtattacat ccaccattgc cgggcggttt ttattcagtg
    14821 tttgcagggc gttattaacc agcgtgtcat cgagggagaa aagcagcgtt ttgttttgca
    14881 tcgccagcga cacgcggaaa aaataatccg acattaattg atcgggttgc gccgcctgcg
    14941 ctttcggata ctgaccgtat cgggaactca cttcgcgacg ccagatttgc gcttcgccct
    15001 gctgagtctg gcttatcggc aaaacacctt ctggcgcttt gctttcgtgc gcaccaatat
    15061 tttgcgtaaa cagtttccct ggcaattgcg cctgttcggc agtgccatca aactgaccga
    15121 caaacagcgg ggtttgcaat tttgagtctg cataccagca cagccccgcg gcaccgtcta
    15181 acgccccatt caacttgtcg ttttcctgac tgatgtgcga aagcatctct tcggcaatac
    15241 cgtgtgaata cggcaccacc acacagaagc tggccccggc aggcatactg ttccagaccg
    15301 gcgtaaaatc gaaactggta tctacgctgg cggattcatc atttaacgcc acaaaactgt
    15361 gccagccgtc gttacccatt tcgaagcgta cgccagcaaa agaaggcatt aaccgctggt
    15421 agccaaaacc cagcaacctg gcgctgacca cgatgcgctg gcgtactggc gttttttcag
    15481 cagcacgctc ttccaggcca aagcttgctt gccagcgttt tttgccgctc aacaaatcac
    15541 ctgcgatcgc cgtggcttcg gtatcctgct gatcatcttt aaacaacata tccgtgctgg
    15601 aaaacaccag catcttgtcc tgataagtcg cgaacatcag ggcgttattg ccgttatagc
    15661 gcaactgata aacaggaaca gtttcactat ttatcttgat gctactgatt tccgttttgc
    15721 ttaactggct gtcgctggta gcggcaaaca acaatggctc cagcagtttg cttaaaccac
    15781 tgcgctggat cagcaccata taatgtgaaa gatggccttg tttatcgtgc cacagcgctg
    15841 cctgcgcggg ctgatctaag agtgacgaaa agagcttatc tttcagcgtg agatcgtgtt
    15901 catagacaat acgacgaatg ctgccttcaa tgcccagacg atcggcatga ttctgataat
    15961 agaaaacgaa atcttcgctc agaacatcgt ggagaaacgg aatggtgagg agatctttgg
    16021 gaagctggct cagagagtcg ctgtcgagaa agaggtccgg ctcattgaga tcgatttgca
    16081 gattgttgtg caccaccagc ggcgacaacg ttttttctgg cccactgcca gcatattgca
    16141 acgcccagac gccagcggaa agcagtgcta ttgcgccaaa acctacaaga ccatagaacc
    16201 gccagccttt cgcctttttt tcaccactca ttgccacatt ccttgtgtat agccagccat
    16261 tttttacggg cacagccaaa ctttaccgtg ccctaatacg acaaaagccc agactttgca
    16321 gcctggactt ttcaattcaa acaagggaga tagctccctt ttggcatgaa gaagtaaaat
    16381 tattcttctt ctggctcgtc gtcaacgtcc acttccggag cgatttcatc gtccccttcc
    16441 gcggcactgc catcgatggt atccagatct tcctcgtcaa ccggttcagc aacacgttgc
    16501 agacccacta cgttttcatc ttccgcagta cggatgagga tcacgccctg ggtgttacgg
    16561 cctacgatgc tgatttccga aacgcgagta cgtaccagcg taccggcatc ggtgatcatc
    16621 atgatctggt cgcagtcatc tacctgtacc gcgccaacca ctaaaccatt acgttcagta
    16681 accttaatgg agataacccc tttcgtcgca cgcgacttgg ttgggtattc cgccactgcg
    16741 gtacgtttac cgtaaccgtt ttgcgttgcg gtgaggattg cgccatcgcc acgaggcacg
    16801 atcagagaga cgactttatc gccttcacct aagcgaatac cgcgaacacc ggtggtgttg
    16861 cagcccatcg cacggacaga agactcttta aagcgcacca ctttaccttc agcggagaac
    16921 agcattactt cgtcttcgcc gctggtcagg tcaacgccga tcagctcatc gccgtcaacc
    16981 agtttgatcg ccactttacc ggcggtacgc agacggttga actcggtgag gacagttttc
    17041 ttcacggtac cgttagcggt cgccatgaag actttcacgc cttcttcaaa ctcggtcact
    17101 ggcaggatcg cagtgatacg ttcgtcctgc tccagcggca gcaggttgac gatcggacga
    17161 ccgcgcgcgc cacgagtggc ttccggcaac tgataaactt tcatcgaata gacgcgacca
    17221 cggctggaga agcacagaat atggtcgtga gtgttcgcca ccagcagtcg gtcgataaag
    17281 tcttcttctt taatacgtgc ggcagattta cctttcccgc cacgacgctg cgcttcgtat
    17341 tcagaaagcg gctgatactt aacgtagccc tggtgagaga gcgtcactac cacatcttcc
    17401 tgagtgatca gatcttccag gttgatgtct gcgctgttgg cggtgatttc agtacgacgt
    17461 ttgtcaccga actgttcacg aaccagctcc agctcttcac ggatcacttc catcaaacga
    17521 tcggcgctac caagaatacg caacagttcc gcgatctgat ccagcagctc tttgtattcg
    17581 tcgagcagtt tttcgtgctc aaggccggtc agtttctgca aacgcagatc cagaatcgcc
    17641 tgagcttgct gttcggtcag gtagtacaga ccatcacgca cgccgaactc tggctccagc
    17701 cattccggac gcgcagcatc gtcgccagca cgttcgagca tcgcggcaac gttgcccagc
    17761 tgccacggat tagcaaccag cgcagttttc gcttctgcag gcgtcggcgc atgacggatc
    17821 agttcgatga tcgggtcgat gttcgccagc gccacggcta atgcttcaag gatatgagca
    17881 cgatcgcgag ctttacgcag ttcgaaaata gtacgacggg tcaccacttc acggcggtga
    17941 cgaacaaacg ccgcgatgat gtctttcagg ttcatgatct tcggctgacc atggtgcaat
    18001 gccaccatgt tgataccgaa agaaacctgc aactgggtct gggagtagag gttgttgagc
    18061 acaacttcac cgaccgcatc gcgtttcact tcaatcacga tgcgcatacc gtctttgtca
    18121 gactcgtcac gcagcgcgct gatgccttcc acgcgttttt cttttaccag ttccgcaatc
    18181 ttctcgatca ggcgcgcttt gtttacctga tacggaattt cgtggacgat aatggtttca
    18241 cgaccggttt tggcgtcaac ttccacttct gcgcgagcgc ggatatacac cttgccgcga
    18301 ccggtacggt aagcttcttc aataccgcga cgaccgttaa tgattgccgc cgtcgggaag
    18361 tccggccccg ggatgtgttc catcagccct tcaatgctga tgtcttcatc atcgatatac
    18421 gccagacaac cgttgatgac ttccgtcagg ttgtgcggcg ggatgttggt tgccatacct
    18481 acggcgatac cggaagaacc gttcaccagc aggttaggaa ttttggttgg catgacgtcg
    18541 ggaatttttt ccgtgccgtc atagttatca acgaaatcga ccgtctcttt ttcgagatcg
    18601 gccatcagtt catgggcaat tttcgccaga cggatttccg tataacgcat tgccgccgca
    18661 gagtcgccgt cgatggaacc gaagttaccc tgaccgtcta ccagcatgta acgcagcgag
    18721 aatggctgcg ccatacggac gatcgtgtca taaaccgccg agtcaccatg gggatggtat
    18781 ttaccgatta cgtcaccaac gacacgggca gattttttat aggctttgtt ccagtcattg
    18841 cctagtacgt tcatggcgta aagtacgcga cggtgtaccg gcttcaggcc atctcggaca
    18901 tctggcagcg cacggccaac aatgaccgac atcgcataat ccagatagga gctcttcagc
    18961 tcttcctcaa tgttgaccgg tgtaatttct ctcgcaaggt cgctcatcta accgctatcc
    19021 ctctactgta tcccggattc aaaggtcgca aattataaca cagccgcgca gtttgaggta
    19081 aacctatacg ctttattcac atccaatgcc tgatatactc gtttgtcttg ccaattacgg
    19141 agtagaagtg ccaatgaatg ccgaaaaatc gccggtaaac cataacgtag accacgaaga
    19201 gatcgctaaa tttgaagccg tcgcctcccg ctggtgggat ctggaaggtg agttcaaacc
    19261 gctgcaccgc attaacccgc tgcgtctggg ctatattgcc gagcgtgctg gcggtttatt
    19321 tggcaaaaag gtgctcgatg tcggttgtgg cggcggcatt ctggccgaga gtatggcgcg
    19381 cgaaggcgcg acggtgaccg gtctggatat gggctttgag ccattgcagg tggcaaaact
    19441 gcacgcactg gaaagcggca ttcaggtgga ttacgtgcag gaaaccgtgg aagagcacgc
    19501 ggcaaaacat gccgggcagt atgatgtggt gacctgcatg gagatgctgg agcacgtccc
    19561 cgatccgcag tcagtggtca gagcctgtgc gcaactggtg aaaccgggcg gcgatgtctt
    19621 tttctcgaca cttaaccgca acggcaagtc atggctgatg gcggtggttg gtgcggaata
    19681 tattttgcgc atggtgccca aaggcacgca tgatgtgaag aagtttatta aaccggcaga
    19741 attgctgggc tgggtagatc agacaagcct taaagagcga catataaccg ggctacatta
    19801 caacccgatc actaatactt ttaaactcgg ccccggcgtg gatgtgaact atatgctgca
    19861 cacgcagaat aagtgaggtt gttgtttggc cgagccaatg cctgatgcga cgcttgccgc
    19921 gtcttatcag gcctacaaat gctccccgta ggccggataa ggcgtttacg ccgcatccgg
    19981 caaccgtgcc gactagacag tgattaccat ttcaccgtca tcgacaaaaa ccctgccgtc
    20041 tgggcaaaat catcactccc tttctgccac gccacgctgc cgcgcaggga cactcgctga
    20101 ctgatattgc ccgtgactcc cacttttatt tcaccccgtc gcttcaccgc atcgtcactg
    20161 atagtgctgc catcttcttc aatttccgtc gcatggggat cgtgataata attcagatct
    20221 aatgttggtg tgacaccaac cgcggtacgc cattcgctgt gtaaacccag ccgcgtctga
    20281 atatcatccc cctgcgattg tgacacgcgc gcatggttag cggcggtaaa atcatcctgc
    20341 tgcacgccct gataaatcac ctgcgcctgc ggttcaatca ccacaccacg ccccggtaac
    20401 cactgatacc cggcttccag cgaggcgata atccccgacg agtggtaatg atctgtgcca
    20461 tcgtcttgtt cggaaacatc attgttaaac cacgcgtatt gcagccagct atccagccag
    20521 gccccctgct tctgattacc gtgctgatac cagcttgagg tcagcccaac ggcataaccg
    20581 tggttctggt tatcggcgcg agttccggtc atattcgagc ggctctcgcc ctgattatca
    20641 ctgtagccac caaccgcccc aagcatccac tcgccatcat cgccccagcg cccgctaaac
    20701 aggtcaccgc taagctgcac cgtagaagtg tcttcatgct gagccagttg ccctgccgcc
    20761 gtgtaatgat aacgtccgcc gataacacgt aaattcagcg tctgaccatt gccacctgca
    20821 tgatcgcgtc gctccatcat aaacgcctga tttgccgccc gcagattatt gagataaccg
    20881 ccaactttgg cattcagcac cggctggtaa gcggggattg gatcgggtgt tgggtcagga
    20941 tcgggtgttg ggtccgggtc tggatcaggt ggcgatggcg gcgttacttc ttgcgatcgc
    21001 agataccagt cgttgttatc ttccactagc gtgtagtcat acgctcccat gttgacgtag
    21061 ccactgccag ccagactgaa ctgtgcattg ttttgaaact gcgtgggatc agctgcgaaa
    21121 tcaaccactt taatgcctgt cgatgtcggc tcaccaatcc ctgtaatgga gttaaccacc
    21181 acagttgtgt tgccagcagt attaccgttc atcaccaatt gatcgcttac cgagtcatcg
    21241 ccgtttaatt cgctgtcgaa cagtagcgta ccgccgccgg tataatcacc gtttaccgtc
    21301 agcgtatcgc cagcgacgcc atttttcagg ctaaccgcac cggacgtatt ggtcagatca
    21361 ccattaaccg tcacgtcggc aagataggtc aggctgtcag tttcaaggtt ggtattaagc
    21421 tcacctgtca acgtcacgcc atcggtagca ttcaccagcg tcccatcgcc gttaaacaat
    21481 gaggcattaa gggcgacgga agtatcctgc ccggtcagac gcaaaaccgt accatcgctg
    21541 atatcgatag tgccgctgga agtagcatcg atagactgaa tatcctgatc cgcgccagta
    21601 acgaacgtcg ccccatcacc gacccacagt gacgaagcat aaggaaagat atccgcaaca
    21661 tcgcctttca gggtgccttc ttcgacacgt actgccgact gcgttgtacc gctggcggtc
    21721 agctccagcg tacccgcccc cgttttagta aatgtgctac cctcatcctg atgctgcccg
    21781 ctgctgtcag ccatcagtgc gccccactgc gtgtctaccc ccgcatcaac tgccacttca
    21841 ccgtcggcgc gcatttcaat atcacgccca tgctcagtcg tcgtagagcg agtatcgaca
    21901 ttggcagtaa tctccatcac gctttcttgt tgcttatcgg taaagataac ctggcggtta
    21961 tagtgggtat ctccaagctg cgagttgtcg ctcaccatca gcgtaccgga ggcgatttgt
    22021 gttgtgccca aataactatt attgtttgcc agacttacct gcccgtcgct cgcatcgacc
    22081 accacgtaga cgccatcttt cccgtcgccg ccgatatgca aattgtcgcc acctgcaaga
    22141 tctaccacat cctgactgcc gataaccgtt ccgctgctgc cactgacttc aaggccatca
    22201 ttgtatgatg tgccgctctg ccaggtggag aaatcagaga gatcgagcac accgccgttt
    22261 aacacgatcg actgcggatc gtcctggaga gcggcgagat ctgccgcgtc gccttccagc
    22321 gaaagcaccg caccatcatc aacgactata tcgccggtta gcgccatcga ctgcgccccc
    22381 gacagcacgt agctgccgtt ttgcgcaatg gtgagctgac cagcaccttc gatggtgcca
    22441 gcaaaactgc cttgattaac agtaacattg ccaccagcat cgatatttaa agtgccattc
    22501 tgaaagcccg tcaatgagtg cacaaaggtt tgttgggtgg agccaacgtt tagctctgcc
    22561 tgattctggt acttatcaat actccctatc gtcagaccgt agcagtcttg cggatcgtcc
    22621 tggcaatgcg tatcgccgac attcatcagg gagttgctgc ggcccagggt aacttcaccg
    22681 ttttcaatct gcatctcacc agtaaagtca ttgttatctg cattaagtac cagatcgccg
    22741 gaacctgttt tggtgatcaa cccggtacca gcaatagagt caacagctcc gtcattctct
    22801 gtattgccaa taaccagcgt ttttccgtcg gcaatatcaa aggtaacttc acttaagccg
    22861 agatacataa agccacccgc cgcagtggaa ggaccatctc catagcctgc tgcgctgttg
    22921 ttctcatcca ctaacacgcc gccgttctgg ctgtagctgt catcaacaga aatatcaata
    22981 agatagggag ccgtcgcgct attggtatat atcgccccgc cataaccttc ggcagtgtta
    23041 tttgtaaagg cagtgttatt tattatcgta taacctgaag gatgcttgct gtcgctatta
    23101 ttatcggtaa catcgattgc cccgccatcg ccatcactgt aacttgttga tgtatatgcc
    23161 tggttgttat caaaaataac atcacttaaa tagacgtcat tattaatggt ataaattgcg
    23221 ccacctttgc catcattagc gatattattg cgaaacatgg cgttagtgac acgtaaatcg
    23281 acggcaccag tatcattagt accagaagaa tagattgcgc caccatcgcc gcctgcgacg
    23341 ttaccagaaa aaataacatc agtaagattc agcgttgagt tttctttagc aaatatggcc
    23401 ccgccgttat tatattctcc tgtaacggtg ttattggcaa acagagtcat tccagtttca
    23461 ttttctggta atagtgaaaa ttccgctcct tgttgcaaaa atacggctcc tccgctggcg
    23521 ttattggtca tatccgaaaa aaccagccat tgcccatcgg cgacactcca gtcctgcgta
    23581 atgcctgaaa ggctttgcct gctggcgtga caactcgctt tgatatcata tccctggcat
    23641 aaatcaatgg ccgccgcgaa accgttagca gagaaaagag atgcaatcat tgacgggagt
    23701 agagataaat actccttgcg tagaaagata atccgcatat tcatctaacc atcattttat
    23761 ataagacggc atatttaaac gcattataca atatgggtta tctttctttt gtaaattgtc
    23821 caacccgatg caatggctat tttgttatta tttgatgaat agtatcagt
//
LOCUS       DAZUDJ010000072        23425 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.072, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000072 DAZUDJ010000000
VERSION     DAZUDJ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23425
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.072"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(108..863)
                     /gene="mlaA"
                     /locus_tag="ACHY1N_003873"
     CDS             complement(108..863)
                     /gene="mlaA"
                     /locus_tag="ACHY1N_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HFS4046087.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNF
                     NVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTR
                     FFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRD
                     DGGDMADGLYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGELKPQENPNAQAIQDDLKDIDSE"
     gene            1157..2089
                     /locus_tag="ACHY1N_003874"
     CDS             1157..2089
                     /locus_tag="ACHY1N_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFS4046088.1"
                     /translation="MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHI
                     RQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIFHVELEGVPGSFLLENLGYTFGF
                     IIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLMRLWGVVLLGNILGTGIAAWAFEY
                     MPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIIL
                     MTWLIALGDTTHIVVGSVEILYLVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMS
                     HAQIRNDMSNKRKAEARQKAERAENIKKNDKNPA"
     gene            2165..2239
                     /locus_tag="ACHY1N_003875"
     tRNA            2165..2239
                     /locus_tag="ACHY1N_003875"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2198..2200,aa:Arg,seq:cct)
     gene            complement(2681..3928)
                     /locus_tag="ACHY1N_003876"
     CDS             complement(2681..3928)
                     /locus_tag="ACHY1N_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide MFS transporter"
                     /protein_id="HFS4046089.1"
                     /translation="MALNIPFRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLT
                     GTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFILVLTGPFMIYVYEPLL
                     QSNFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFF
                     AGIFFSISPHINFWLVSLFGAVFMMINMRFKDKDHQCVAADAGGVKKEDFIAVFKDRN
                     FWVFVIFIVGTWSFYNIFDQQLFPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAI
                     IPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPLCVISVFKY
                     SVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLL
                     FGIFFLSKKREQIVMETPVPSAI"
     gene            complement(4000..4914)
                     /locus_tag="ACHY1N_003877"
     CDS             complement(4000..4914)
                     /locus_tag="ACHY1N_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoimidazole riboside kinase"
                     /protein_id="HFS4046090.1"
                     /translation="MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGT
                     SGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVR
                     PSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTAIRHAGGFVSFDPNIR
                     EDLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLV
                     TKGAEGVVVCYRGQVHHFAGMSVNCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRI
                     IDLAQRCGALAVTAKGAMTALPCRQELE"
     gene            5130..6563
                     /gene="cscA"
                     /locus_tag="ACHY1N_003878"
     CDS             5130..6563
                     /gene="cscA"
                     /locus_tag="ACHY1N_003878"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFS4046091.1"
                     /translation="MTQSRLHAAQNALAKLHEHRGNTFYPHFHLAPPAGWMNDPNGLI
                     WFNDRYHAFYQHHPMSEHWGPMHWGHATSDDMIHWQHEPIALAPGDDNDKDGCFSGSA
                     VDDNGVLSLIYTGHVWLDGAGNDDAIREVQCLATSRDGIHFEKQGVILTPPEGIMHFR
                     DPKVWREADTWWMVVGAKDPGNTGQILLYRGSSLREWTFDRVLAHADAGESYMWECPD
                     FFSLGDQHYLMFSPQGMNAEGYSYRNRFQSGVIPGMWSPGRLFAQSGHFTELDNGHDF
                     YAPQSFLAKDGRRIVIGWMDMWESPMPSKREGWAGCMTLARELSESNGKLLQRPVHEA
                     ESLRQQHQSVSPRTISNKYVLQENAQAVEIQLQWALKNSDAEHYGLQLGTGMRLYIDN
                     QSERLVLWRYYPHENLDGYRSIPLPQRDTLALRIFIDTSSVEVFINDGEAVMSSRIYP
                     QPEERELSLYASHGVAVLQHGALWLLG"
     gene            complement(6571..7566)
                     /locus_tag="ACHY1N_003879"
     CDS             complement(6571..7566)
                     /locus_tag="ACHY1N_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005088955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4046092.1"
                     /translation="MASLKDVARLAGVSMMTVSRVMHNAESVRPATRDRVLQAIQTLN
                     YVPDLSARKMRAQGRKPSTLAVLAQDTATTPFSVDILLAIEQTASEFGWNSFLINIFS
                     EDDAARAARQLLAHRPDGIIYTTMGLRHITLPESLYGENIVLANCVADDPALPSYIPD
                     DYTAQYESTQHLLAAGYRQPLCFWLPESALATGYRRQGFEQAWRDAGRDLAEVKQFHM
                     ATGDDHYTDLASLLNAHFKPGKPDFDVLICGNDRAAFVAYQVLLAKGVRIPQDVAVMG
                     FDNLVGVGHLFLPPLTTIQLPHDIIGREAALHIIEGREGGRVTRIPCPLLIRCST"
     gene            7809..8027
                     /locus_tag="ACHY1N_003880"
                     /pseudo
     CDS             7809..8027
                     /locus_tag="ACHY1N_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
     gene            8045..9373
                     /gene="dsdA"
                     /locus_tag="ACHY1N_003881"
     CDS             8045..9373
                     /gene="dsdA"
                     /locus_tag="ACHY1N_003881"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008721 - D-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0046416 - D-amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HFS4046093.1"
                     /translation="MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGL
                     TEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQ
                     LLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQ
                     YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV
                     AVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYL
                     PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNL
                     TAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA
                     GPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR"
     gene            complement(9481..11019)
                     /gene="emrY"
                     /locus_tag="ACHY1N_003882"
     CDS             complement(9481..11019)
                     /gene="emrY"
                     /locus_tag="ACHY1N_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HFS4046094.1"
                     /translation="MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTI
                     SGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSL
                     STNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPI
                     LGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVG
                     GLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWESTSENPILDLSLFKSRNFTI
                     GIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNK
                     IDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFS
                     GLPDNKFANASSMSNFFRTLSGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSS
                     SQIMDKYYGSLSGVLNEINNEITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTA
                     KGVG"
     gene            complement(11019..12182)
                     /gene="emrK"
                     /locus_tag="ACHY1N_003883"
     CDS             complement(11019..12182)
                     /gene="emrK"
                     /locus_tag="ACHY1N_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrK"
                     /protein_id="HFS4046095.1"
                     /translation="MEQINSNKKHSNRRKYFSLLAVVLFIAFSGAYAYWSMELEDMIS
                     TDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGDILVSLDKTDATIALNKAKNNLA
                     NIVRQTNKLYLQDKQYSAEVASARIQYQQSLEDYNRRVPLAKQGVISKETLEHTKDTL
                     ISSKAALNAAIQAYKANKALVMNTPLNRQPQVVEAADATKETWLALKRTDIRSPVTGY
                     IAQRSVQVGETVSPGQSLMAVVPARQMWVNANFKETQLTDVRIGQSVNIISDLYGENV
                     VFHGRVTGINMGTGNAFSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEHPLRIGLSM
                     TATIDTKNEDIAEMPDLASTVTSMPAYTSKALVIDTSPIEKEISNIISHNGQL"
     gene            12598..13212
                     /gene="evgA"
                     /locus_tag="ACHY1N_003884"
     CDS             12598..13212
                     /gene="evgA"
                     /locus_tag="ACHY1N_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system DNA-binding response
                     regulator EvgA"
                     /protein_id="HFS4046096.1"
                     /translation="MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETL
                     KPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSK
                     KEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKD
                     NNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG"
     gene            13217..16810
                     /gene="evgS"
                     /locus_tag="ACHY1N_003885"
     CDS             13217..16810
                     /gene="evgS"
                     /locus_tag="ACHY1N_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0010447 - response to acidic pH [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system histidine kinase EvgS"
                     /protein_id="HFS4046097.1"
                     /translation="MKFLPYFFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPVRL
                     SNKELRWLASKKNLVIAVHKSQTATLLHTDSQQQVRGINADYLNLLKRALNIKLTLRE
                     YADHQKAMDALAEGEVDIVLSHLVTSPPLNSDIAATKPLIITFPALVTTLHDSMRPLT
                     SPKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGQNDYFIGSNIITSS
                     MISRYFTHSLNVVKYYNSPRQYNFFLTRKESVILNEVLNRFVDALTNEVRYEVSQNWL
                     DTGNLAFLNKPLELTEHEKQWIKQHPDLKVLENPYSPPYSMTDENGSVRGVMGDILNI
                     ITLQTGLNFSPITVSHNIHAGTQLNPGGWDIIPGAIYSEDRENNVSFAEAFITTPYVF
                     VMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIQVDNASAAFHKVKEGELD
                     ALVATQLNSRYMIDHYYPNELYHFLIPGVPNASLSFAFPRGEPELKDIINKALNAIPP
                     SEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKV
                     IQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENS
                     DSPFKDVFSNAHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASDNAVYI
                     CGWQDITETRDLINALEVEKNKAIKATVAKSQFLATMSHEIRTPISSIMGFLELLSGS
                     GLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHS
                     FGAIAASKSIALSCSSTFPDHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLV
                     HIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNM
                     QGDLSLESHPGIGTTFTITIPVEISQQVATVEAKAEHPITLPEKLSILIADDHPTNRL
                     LLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFELTRKLREQNSS
                     LPIWGLTANAQANEREKGLSCGMNLCLFKPLTLDVLKTHLSQLHQVAHIAPQYRHLDI
                     EALKNNTANDLQLMQEILMTFQHETHKDLPAAFQALEAGDNRTFHQCIHRIHGAANIL
                     NLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIAVFCQKND"
     gene            complement(16866..18011)
                     /gene="yfdE"
                     /locus_tag="ACHY1N_003886"
     CDS             complement(16866..18011)
                     /gene="yfdE"
                     /locus_tag="ACHY1N_003886"
                     /EC_number="2.8.3.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416872.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA:oxalate CoA-transferase"
                     /protein_id="HFS4046098.1"
                     /translation="MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPP
                     GHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFR
                     PGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
                     DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMA
                     YIATGKSPQRLGNRHPYMAPFDVFNTQDKPITICCGNDKLFSALCQALELTELVNDPR
                     FSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPLLSVAEAIKLPQTQA
                     RNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS"
     gene            complement(18085..19029)
                     /gene="yfdV"
                     /locus_tag="ACHY1N_003887"
     CDS             complement(18085..19029)
                     /gene="yfdV"
                     /locus_tag="ACHY1N_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter YfdV"
                     /protein_id="HFS4046099.1"
                     /translation="MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYA
                     LPAALFVSITRANREMIFADTRLTLVSLVVIVGCFFFSWFGCYKFFKRTHAEAAVCAL
                     IAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKK
                     NSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLT
                     LAAHKFEFSAEIAYNTFLKLILMPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGII
                     IASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS"
     gene            complement(19099..20793)
                     /gene="oxc"
                     /locus_tag="ACHY1N_003888"
     CDS             complement(19099..20793)
                     /gene="oxc"
                     /locus_tag="ACHY1N_003888"
                     /EC_number="4.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008949 - oxalyl-CoA decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0033611 - oxalate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxalyl-CoA decarboxylase"
                     /protein_id="HFS4046100.1"
                     /translation="MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAE
                     GIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMI
                     SGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPG
                     GVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIIL
                     GKGAAYSQADEQLREFIESTQIPFLPMSMAKGILEDTHPLSAAAARSFALANADVVML
                     VGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELK
                     QNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLV
                     NEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
                     GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDA
                     FRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN"
     gene            complement(20847..22097)
                     /gene="frc"
                     /locus_tag="ACHY1N_003889"
     CDS             complement(20847..22097)
                     /gene="frc"
                     /locus_tag="ACHY1N_003889"
                     /EC_number="2.8.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033608 - formyl-CoA transferase activity
                     [Evidence IEA];
                     GO_process: GO:0033611 - oxalate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formyl-CoA transferase"
                     /protein_id="HFS4046101.1"
                     /translation="MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDV
                     TRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAI
                     DHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPP
                     LVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRL
                     DKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQN
                     WENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIP
                     CAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEH
                     TAAVLQELGYSDDEIAAMKQNHAI"
     gene            complement(22610..23242)
                     /locus_tag="ACHY1N_003890"
     CDS             complement(22610..23242)
                     /locus_tag="ACHY1N_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HFS4046102.1"
                     /translation="MKRLIMATMVTAILASSTVWAADNAPVAAQQQTQQVQQTQKTAA
                     AERISEQGLYAMRDVQVARLALFHGDPEKAKELTNEASALLSDDSTEWAKFAKPGKKT
                     NLNDDQYIVINASVGISESYVATPEKEAAIKIANEKMAKGDKKGAMEELRLAGVGVME
                     NQYLMPLKQTRNALADAQKLLDKKQYYEANLALKGAEDGIIVDSEALFVN"
BASE COUNT         6710 a         5476 c         5095 g         6144 t
ORIGIN      
        1 acatcattac gtccgggtca ttgtcggttt atctcctttt acttgtggta attgagggat
       61 aacaacaaaa aaggtgagta ttgcgactca ccttttttat ttgtttctta ttcagaatcg
      121 atatctttta aatcatcctg aatcgcttgc gcgttcggat tttcctgcgg tttgagttcg
      181 ccgccattag cgatgaaatc atgacgctgg aagtacgctt cgcgcaccat aatataagga
      241 tcggacgact gacgcagcag accatcggaa tccaacaact gcgcacgagt ttctatccct
      301 tcaagcgtcc atttacccac agacatcggc caggtcagcc aggaaagaac cgggtaaaga
      361 ccatccgcca tatcaccacc gtcatcacgc agcgtgaagc taccgtagaa cggtaactgg
      421 acgtaaggcc cataacccac gccataatga ccaagcgtac taccgaagcg gtgaggttca
      481 gtccgttgca gtttcgggtt cgccatccct gcaacatcaa taaaaccgcc catccccaaa
      541 atggtgttca ggaaaaagcg ggtaaagtgg accatcccct gataagggtc gccctgcaag
      601 aagtagttaa ccatcaccgc aggttcttca aggttgccag taaagttgct caaaccgtta
      661 cgcgccggtt gcggaacata atcacgccag gcgacagcga ccggtcgaac aatatacggg
      721 tctaatacat tgaagttgaa gttgtacatg gtgcggttga acccttctaa cgggtcagaa
      781 cgcccttgct gatctgtacc ggaactcgca caccccacca gaagcgtagt tcccagagca
      841 agcgccgaca ggcgaagctt cataaatgtc tccctgtttt tttatggctt atgcagtttg
      901 ccatccatga cggaacgata ccgtatccgc ctgtttaggt gtgggcgatt gtaacagcac
      961 gtcaactgat gtccagacgc cctgatttgc tgatttgatc atagcctggt aatcgccgcc
     1021 ctgtaggcta cttgattcta tagaaacaga aaaaggcaaa cgcagccttt tctacatttt
     1081 cagagtaact cccgccagtt gcgagcaaaa aagccgctac gctttagcta tacgtgctaa
     1141 ttcaagagaa gagaccatgg acaacgacaa aattgatcaa cacagcgacg aaattgaagt
     1201 tgagagcgaa gaaaaagagc gcggcaaaaa aatagaaata gatgaagacc gactcccctc
     1261 ccgggcgatg gcaattcatg agcatatccg ccaggatggt gaaaaagagc tggaacgcga
     1321 cgcaatggcg ctactgtggt cagccattgc ggcgggtctg tcgatgggcg cttcgctact
     1381 ggcaaaaggg atatttcatg tcgaactgga aggagtgcca ggcagcttct tactggagaa
     1441 tctcggttat acctttggtt ttattatcgt cattatggcc cgccagcaat tatttaccga
     1501 aaacaccgtg actgcggtac tacccgtcat gcaaaaaccg acaatgagca acgtcggctt
     1561 acttatgcga ttatggggcg tcgtgctgct gggtaatatt ctcgggacag gtattgctgc
     1621 atgggcattt gaatatatgc ctatcttcaa tgaagaaact cgcgatgcat ttgtcaaaat
     1681 cggcatggat gtgatgaaga acacccccag cgagatgttt gccaacgcga tcatttccgg
     1741 ctggctgatc gccactatgg tttggatgtt tcctgctgcg ggtgcggcaa agattgtggt
     1801 gattatattg atgacctggc ttattgcact gggtgacacc acccacatcg ttgtcggttc
     1861 tgttgaaatc ctctatctgg tgtttaacgg cacgctgcac tggagcgatt tcatctggcc
     1921 cttcgcacta cctactttag cggggaacat ctgcggcggc acctttatct tcgcgttaat
     1981 gagtcatgca cagattcgta acgacatgag caacaagcgt aaagcagaag cacgccaaaa
     2041 agcagaacgt gcggaaaaca ttaagaaaaa tgataaaaac ccagcataaa tggcgagggt
     2101 ttaagcaatc gagcggcagc gtacttaccc cgcagtccat tagcgggtat actcatgccg
     2161 cattgtcctc ttagttaaat ggatataacg agcccctcct aagggctaat tgcaggttcg
     2221 attcctgcag gggacaccag atacccttca aacgaaatct accttcaccc cgtaaaagat
     2281 gggtttggca gcacacttgc cttatatcta ctcattttta ctgcaacagg ttgaaatctc
     2341 agcactgtca gaaagcgctg atgactaaac agccctgggc cgggcgatgt aaccatcaca
     2401 cagaatcctg atagcgaaat atggcgtgac tcgatacttc actccgcaat gcattccttg
     2461 atgaattcgc aggaccgtga tacacgggac aggtcactga atgacgacaa tgtcctggaa
     2521 atcagcgaac cgcgcatctg aagtacattt gagcgactgt accagaacat gaatgaggcg
     2581 tttggattag gcgattatta gcagggctaa gcattttact attattattt tccggttgag
     2641 ggatatagag ctatcgacaa caaccggaaa aagtttacgt ctatattgct gaaggtacag
     2701 gcgtttccat aactatttgc tcgcgttttt tactcaagaa gaaaatgcca aatagcaaca
     2761 tcaggcagac aatacccgaa attgcgaaga aaactgtctg gtagcctgcg tggtcaaaga
     2821 gtatcccagt cggcgttgaa agcagcacaa tcccaagcga actggcaatt tgaaaaccaa
     2881 tcagaaagat cgtcgacgac aggcgcttat caaagtttgc cacgctgtat ttgaagacgg
     2941 atatgacaca aagtggaacc tcaatggcat gtaacaactt cactaatgaa ataatccagg
     3001 ggttaacgaa cagcgcgcag gaaaggatac gcaacgccat aatcacaact ccgataagta
     3061 atgcattttt tggccctacc cgattcacaa agaaaggaat aatcgccatg cacagcgctt
     3121 cgagtaccac ctggaatgag ttgagataac catacaggcg cgttcctaca tcgtgtgatt
     3181 cgaataaacc tgcataaaag acaggaaaaa gttgttgatc aaaaatgtta tagaaagacc
     3241 acgtccccac aataaatatg acgaaaaccc agaagtttcg atccttgaaa actgcgataa
     3301 aatcctcttt ttttacccct cccgcatctg ccgctacgca ctggtgatcc ttatctttaa
     3361 aacgcatgtt gatcatcata aatacagcgc caaatagcga gaccaaccag aagttgatat
     3421 ggggactgat actaaaaaat atgccggcaa agaacgcgcc aatagcatag ccaaaagatc
     3481 cccaggcgcg cgctgttcca tattcgaaat gaaaatttcg cgccattttt tcggtgaagc
     3541 tatcaagcaa accgcatccc gccagatacc ccaagccaaa aaatagcgcc cccagaatta
     3601 gacctacaga aaaattgctt tgcagtaacg gttcataaac gtaaatcata aacggtccgg
     3661 tcaagaccag gatgaaactc atacaccaga tgagcggttt cttcagaccg agtttatcct
     3721 gaacgatgcc gtagaacatc ataaatagaa tgctggtaaa ctggttgacc gaataaagtg
     3781 tacctaattc cgtccctgtc aaccctagat gtcctttcag ccaaatagcg tataacgacc
     3841 accacagcga ccaggaaata aaaaagagaa atgagtaact ggatgcaaaa cgatagtacg
     3901 catttctgaa tggaatattc agtgccataa ttacctgcct gtcgttaaaa aattcacgtc
     3961 ctatttagag ataagagcga cttcgccgtt tacttctcac tattccagtt cttgtcgaca
     4021 tggcagcgct gtcattgccc ctttcgccgt tactgcaagc gctccgcaac gttgagcgag
     4081 atcgataatt cgtcgcattt ctctctcatc tgtagataat cccgtagagg acagacctgt
     4141 gagtaacccg gcaacgaacg catctcccgc ccccgtgcta tcgacacaat tcacagacat
     4201 tccagcaaaa tggtgaactt gtcctcgata acagaccacc acaccttctg cacctttagt
     4261 caccaacagc atggcgatct catactcttt tgccagggcg catatatccc gatcgttctg
     4321 tgtttttcca ctgataagtc gccattcttc ttccgagagt ttgacgacat ccgccagttg
     4381 tagcgcctgc cgcaaacaca agcggagcaa atgctcgtct tgccatagat cttcacgaat
     4441 attaggatcg aagctgacaa aacctccggc atgccggatc gccgtcatcg cagtaaatgc
     4501 gctggtacgc gaaggctcgg cagacaacgc aattgaacag agatgtaacc attcgccatg
     4561 tcgccagcag ggcaagtctg tcgtctctaa aaaaagatcg gcactggggc ggaccataaa
     4621 cgtaaatgaa cgttcccctt gatcgttcag atcgacaagc accgtggatg tccggtgcca
     4681 ttcatcttgc ttcagatacg tgatatcgac tccctcagtt agcagcgttc tttgcattaa
     4741 cgcaccaaaa ggatcatccc ccacccgacc tataaaccca cttgttccgc ctaatctggc
     4801 gattcccacc gcaacgttag ctggcgcgcc gccaggacaa ggcagtaggc gcccgtctga
     4861 ttctggcaag agatctacga ccgcatcccc taaaacccat actttggctg acattttttt
     4921 cccttaaatt catctgagtt acgcatagtg ataaacctct ttttcgcaaa atcgtcatgg
     4981 atttactaaa acatgcatat tcgatcacaa aacgtcatag ttaacgttaa catttgtgat
     5041 attcatcgca tttatgaaag taagggactt tatttttata aaagttaacg ttaacaattc
     5101 accaaatttg cttaaccagg atgattaaaa tgacgcaatc tcgattgcat gcggcgcaaa
     5161 acgccctagc aaaacttcat gagcaccggg gtaacacttt ctatccccat tttcacctcg
     5221 cgcctcctgc cgggtggatg aacgatccaa acggcctgat ctggtttaac gatcgttatc
     5281 acgcgtttta tcaacatcat ccgatgagcg aacactgggg gccaatgcac tggggacatg
     5341 ccaccagcga cgatatgatc cactggcagc atgagcctat tgcgctagcg ccaggagacg
     5401 ataatgacaa agacgggtgt ttttcaggta gtgctgtcga tgacaatggt gtcctctcac
     5461 ttatctacac cggacacgtc tggctcgatg gtgcaggtaa tgacgatgca attcgcgaag
     5521 tacaatgtct ggctaccagt cgggatggta ttcatttcga gaaacagggt gtgatcctca
     5581 ctccaccaga aggaatcatg cacttccgcg atcctaaagt gtggcgtgaa gccgacacat
     5641 ggtggatggt agtcggggcg aaagatccag gcaacacggg gcagatcctg ctttatcgcg
     5701 gcagttcatt gcgtgaatgg accttcgatc gcgtactggc ccacgctgat gcgggtgaaa
     5761 gctatatgtg ggaatgtccg gactttttca gccttggcga tcagcattat ctgatgtttt
     5821 ccccgcaggg aatgaatgcc gagggataca gttaccgaaa tcgctttcaa agtggcgtaa
     5881 tacccggaat gtggtcgcca ggacgacttt ttgcacaatc cgggcatttt actgaacttg
     5941 ataacgggca tgacttttat gcaccacaaa gctttttagc gaaggatggt cggcgtattg
     6001 ttatcggctg gatggatatg tgggaatcgc caatgccctc aaaacgtgaa ggatgggcag
     6061 gctgcatgac gctggcgcgc gagctatcag agagcaatgg caaacttcta caacgcccgg
     6121 ttcacgaagc tgagtcgtta cgccagcagc atcaatctgt ctctccccgc acaatcagca
     6181 ataaatatgt tttgcaggaa aacgcgcaag cagttgagat tcagttgcag tgggcgctga
     6241 agaacagtga tgccgaacat tacggattac agctcggcac tggaatgcgg ctgtatattg
     6301 ataaccaatc tgagcgactt gttttgtggc ggtattaccc acacgagaat ttagacggct
     6361 accgtagtat tcccctcccg cagcgtgaca cgctcgccct aaggatattt atcgatacat
     6421 catccgtgga agtatttatt aacgacgggg aagcggtgat gagtagtcga atctatccgc
     6481 agccagaaga acgggaactg tcgctttatg cctcccacgg agtggctgtg ctgcaacatg
     6541 gagcactctg gctactgggt taacataata tcaggtggaa caacggatca acagcgggca
     6601 agggatccgc gtcactcttc ccccttcacg accttcaata atatgcaatg cagcttcccg
     6661 cccgataatg tcatgtggaa gctgaattgt ggtcagcggc ggtaaaaaca gatgcccgac
     6721 gccaaccaga ttatcaaagc ccattacggc gacatcctgc gggatacgta cccccttcgc
     6781 caggagaacc tgataagcga caaaggctgc gcgatcgtta ccacatatca gaacatcaaa
     6841 atctggtttg cccggtttga agtgggcatt gagtaaactt gcgagatcgg tgtagtgatc
     6901 atcacctgtt gccatgtgaa attgtttcac ctcagccaga tctcgtccag catcacgcca
     6961 ggcctgctca aatccctgcc gacgataccc tgttgccaac gcactttccg gtagccagaa
     7021 gcataacggt tgacgatagc ccgccgcgag caaatgctgt gttgattcat attgtgcagt
     7081 gtaatcatca gggatataac tgggtaacgc tgggtcatcc gccacacagt tcgccaatac
     7141 aatattttca ccatacagag actcaggcag cgtgatatgt cgcagcccca ttgtagtata
     7201 gataatgcca tccggacggt gggcaagcag ctgacgtgcc gcgcgggcag cgtcatcttc
     7261 agaaaaaata ttgattaaaa aactattcca gccgaactcg ctggcggttt gctcaatggc
     7321 aagcagaata tcaacagaga aaggagtggt agccgtgtcc tgcgccagca cggcgagagt
     7381 cgacggctta cgtccttgag cgcgcatctt acgggcggaa agatcaggaa cataattcag
     7441 ggtctggatt gcctgcaata cgcggtcacg cgttgcagga cgcacagatt ctgcattatg
     7501 catcacccgg gagactgtca tcatcgacac tcccgccagg cgtgcgacat cctttaatga
     7561 agccataccc aagccgtttg ccgtaaaacg ggcactgtag cagaaacaga cgtcactggc
     7621 gagatccaac gatattctca acgccctatc acccaacacg gcaatacaat aaaaaataac
     7681 aataattgcc ggataattgt actcaattcc gcctctgttc tcgccaacga gtaaccatat
     7741 aggcaagtaa gtaaaacatg ccaactggca tcgccaacct ggagaagaaa atataaatat
     7801 ggatcattgt gctgccgctg tatcccgaca tcagcccgga aattattgcg attgctatcg
     7861 gttcaggtgc aattggctgc acgatcgtta cggactcgct tttctggcta gtgaagcaat
     7921 attgcggcgc tacgctcaat gaaacattta aatactatac gacagcgaca tttatcgctt
     7981 cagtcgtcgc tctggcgggc acattcctgc tgtcatttat catctaagcg caaagagacg
     8041 tactatggaa aacgctaaaa tgaactcgct catcgcccag tatccgttgg taaaggatct
     8101 ggttgctctt aaagaaacca cctggtttaa tcctggcacg acctcattgg ctgaaggttt
     8161 accttatgtt ggcctgaccg aacaggatgt tcaggacgcc catgcgcgct tatcccgttt
     8221 tgcaccctat ctggcaaaag catttcctga aactgctgcc actgggggga ttattgaatc
     8281 agaactggtt gccattccag ctatgcaaaa acggctggaa aaagaatatc agcaaccgat
     8341 cagcgggcaa ctgttactga aaaaagatag ccatttgccc atttccggct ccataaaagc
     8401 acgcggcggg atttatgaag tcctggcaca cgcagaaaaa ctggctctgg aagcggggtt
     8461 gctgacgctt gatgatgact acagcaaact gctttctccg gagtttaaac agttctttag
     8521 ccaatacagc attgctgtgg gctcaaccgg aaatctgggg ttatcaatcg gcattatgag
     8581 cgcccgcatt ggctttaagg tgacagttca tatgtctgct gatgcccggg catggaaaaa
     8641 agcgaaactg cgcagccatg gcgttacggt cgtggaatat gagcaagatt atggtgttgc
     8701 cgtcgaggaa ggacgtaaag cagcgcagtc tgacccgaac tgtttcttta ttgatgacga
     8761 aaattcccgc acgttgttcc ttgggtattc cgtcgctggc cagcgtctta aagcgcaatt
     8821 tgcccagcaa ggccgtatcg tcgatgctga taaccctctg tttgtctatc tgccgtgtgg
     8881 tgttggcggt ggtcctggtg gcgtcgcatt cgggcttaaa ctggcgtttg gcgatcatgt
     8941 tcactgcttt tttgccgaac caacgcactc cccttgtatg ttgttaggcg tccatacagg
     9001 attacacgat cagatttctg ttcaggatat tggtatcgac aaccttaccg cagcggatgg
     9061 ccttgcagtt ggtcgcgcat caggctttgt cgggcgggca atggagcgtc tgctggatgg
     9121 cttctatacc cttagcgatc aaaccatgta tgacatgctt ggctggctgg cgcaggaaga
     9181 aggtattcgt cttgaacctt cagcactggc gggtatggcc ggacctcagc gcgtgtgtgc
     9241 atcagtaagt taccaacaga tgcacggttt cagcgcagaa caattgcgta atgccactca
     9301 tctggtgtgg gcgacgggag gtggaatggt gccggaagaa gagatgaatc aatatctggc
     9361 aaaaggccgt taataacgtt tcaacgcagc atcgcaatcc tttccctggg tgagcgatgc
     9421 tgccgatggc gcagacttaa gatccccggt cttacccgct ataaccccct ccttttatca
     9481 tcacccaacg cctttcgctg taaacggcgg tttcgcaaac caaaccaaaa ccgtaagtaa
     9541 gataaaagca atagccgcca tacggaaaat ctcatttgca gaaatagaaa gtgactgctg
     9601 ggttatttca ttattaattt cattaagaac tcctgaaagc gaaccatagt atttatccat
     9661 aatttgtgac gatgaattaa acacggggtt aaattgatcg atggttgctg tcaactgact
     9721 atggtgtaac gattcgcgtc gtccccacag cgtcattgtc aacgacgtac caactgatcc
     9781 tgacaaggta cgaaaaaaat tactcatact cgaggcattg gcaaatttat tatctggcaa
     9841 gcctgaaaac gaaatcgttg ttaagggtaa aaagaaacag gcaacggcga atccctgaaa
     9901 aaactgcggc aaaatgatgc ctgtaaaatc aatcgttggc ataaatgtca cagaacgcca
     9961 gtaatagcaa accgcataca tcaaaaaact aaatgtcact aacaaccgca tgtctatttt
    10021 gttgccataa cgtcctatca aaggtgaaat taatagtggc atgatgccga tgggcgcata
    10081 agcaagtccg gcccatatcg cattataccc catcgtttcc tggagtaact gcggcataag
    10141 gacgatcgct ccagagtaaa ataaatacgc gcatgtgata ctcacaatac caatggtgaa
    10201 gttacgggac ttaaacaaac tgagatcaag aatcgggttc tctgaggtcg actcccaaat
    10261 gactaaagag atcagagaaa taactgatac tactgttaat attattattg tactcgagtt
    10321 gaaccaatcc agatcgcgcc ctttatcaag cataatttgc aagccaccaa caccgagcac
    10381 taacagggtc agtcctggta gattcatttt gaccggtgaa gtttcagttt ctcttccttt
    10441 aagtaaggtt aagcataatg tcaggacgat aatccccata gggacattga ttaaaaatat
    10501 ccaaccccag ctaaagttat cgcaaatata accgcccaat atcggcccac atatcggagc
    10561 gataatcacg gtcattgacc ataatgccag agcaaatgtt cttttttctg gtggataatt
    10621 ccttaataat aaactctgtg acagtggaat taacggcccc gccattaatc cctgaacgac
    10681 tctaaaaaat atcagcacat caagattggt cgataaacta cacattaagg aagacagcga
    10741 aaaaaaagtg actgaaagta aaaataacct taattcgcct attctttgtg ccagcctgcc
    10801 ggtaacaggg atcgcaatgg catttgctac gccaaacgag gtgataaccc aggtgccttc
    10861 gtctgttgat gctcccagaa agccagatat tgtcggtatt gcgacgttag aaatagtgga
    10921 atccaacatt tgcataaacg tcgctaatga caatgcaata gtaacgcacc ataacgtccc
    10981 accggttaat ggtgccggag tcgatttagt gattgccatt aaagttgtcc attatgcgaa
    11041 ataatgttgc taatttcttt ttctatcgga ctggtatcga taactaaagc cttactggta
    11101 taagccggca tggacgtcac ggttgaagcc agatcaggca tctcagcaat gtcttcgttc
    11161 ttcgtatcaa tagttgcagt catcgataaa ccaatgcgta aggggtgttc catgagttct
    11221 tttggatcaa gagaaacttc aaccggtaca cgctgaacga ttttgatcca gttccctgtc
    11281 gcattttgtg caggtaataa ggagaacgca ttgccggttc ccatattgat ccctgtcacc
    11341 cgaccatgaa acacaacatt ttcaccataa agatcgctga taatattgac tgattgacca
    11401 atccgtacat ccgtgagttg tgtttcttta aagttggcat taacccacat ttgacgtgcc
    11461 ggtacgacag ccattaacga ttgtccggga ctcactgttt cgccgacctg aacactccgc
    11521 tgggcaatat agccagtaac cggactcctt atatccgtac gtttaagcgc caaccaggtt
    11581 tctttagttg catccgccgc ttccacgact tgtggctgac ggtttaatgg tgtgttcatt
    11641 actaaagctt tattcgcttt ataagcctgg atagcggcat tcagtgccgc tttgctactt
    11701 attaacgtat ctttggtatg ctccagcgtt tcttttgaaa taaccccctg cttcgctaac
    11761 ggtactcgac ggttataatc ttctaaagat tgttgatact gaatacgtgc tgaagcgact
    11821 tcggcactgt attgtttatc ctgtaagtac agtttattcg tttgccgaac aatatttgcc
    11881 agattatttt tagctttatt gagtgcgata gtggcatcag ttttatccag tgaaactaaa
    11941 atgtcacctt gtcgaacgta gttcgtatct ttatgattaa cgacagtgac actacctgag
    12001 acttgtgcag aaattggatc tgcattcccc gtgacatagg cgtcatctgt actaatcatg
    12061 tcttctaatt ccattgacca ataggcatag gcacctgaaa acgcaataaa taaaactacc
    12121 gccaataaag aaaagtattt tcttctgtta gaatgttttt tatttgaatt aatctgttcc
    12181 actattatct ctcatttctc atagatgaaa tttatgaatt gaatgaaaag agcattcatt
    12241 cttcatatca aacacagtgc atgtgttgca cattatccca ggaacgttgg aggcctaatt
    12301 taaatgaggt gcaaaaaaaa caacagagga ctaaaccgtg gcttttgcaa tacaattctt
    12361 acgcctgtag gattagtgag aagacttata gtgctaactt gaaactataa atcatcggta
    12421 taatccctga ttttattgtt gacatttcat ttatgccgac tatttatatg gtatacttgt
    12481 cgaattatct taaaggaagc tcagattttc ttatttttat tgagaaaatg agatgacgcc
    12541 ttatgtctgt attactacag ggagaaggga gatgcttcat tgcaaaggga ataatctatg
    12601 aacgcaataa ttattgatga ccatcctctt gctatcgcag caattcgtaa tttattgatc
    12661 aaaaacgata ttgaaatctt agcggagttg actgaagggg gaagcgccgt tcagcgggtg
    12721 gaaacactta agcctgatat cgtcatcatt gatgtcgata tccccggagt taacggtatc
    12781 caggtgttag aaacgctgag gaagcgccaa tatagcggaa ttattattat tgtctccgct
    12841 aaaaatgacc atttttacgg gaaacattgt gctgatgctg gcgctaatgg attcgtgagt
    12901 aaaaaagaag gcatgaacaa tatcattgcg gctattgaag ctgcaaaaaa tggctactgc
    12961 tatttcccct tctctctcaa ccggtttgtt ggaagtttaa cgtccgacca gcaaaaactc
    13021 gactccttat cgaaacaaga aattagtgtc atgcggtata ttcttgatgg caaggataat
    13081 aatgacattg ctgaaaaaat gttcatcagc aacaaaactg tcagcactta taaaagtcgc
    13141 ctgatggaaa aattagaatg taaatcactg atggatcttt acacattcgc gcaacgtaac
    13201 aaaatcggct aatcacatga agtttttacc ctattttttt cttctctgtt gtggtctttg
    13261 gtcgaccata agtttcgcag acgaagatta catcgaatat cgtggcatca gtagtaacaa
    13321 ccgtgtcaca cttgatccag tacgtctgag caacaaggaa ttacgttggt tagcgagcaa
    13381 aaaaaatctt gtgattgcag tacacaagtc ccaaacggct accttgttgc ataccgattc
    13441 gcagcaacag gttcgtggta ttaatgctga ttatttaaat cttttaaaaa gagcgttaaa
    13501 tatcaaatta acactccggg aatacgccga tcatcaaaaa gcaatggacg cgcttgcaga
    13561 aggtgaagtc gatatagtgt tatcacattt agttacttcg ccgcctctta atagtgacat
    13621 tgctgcaacc aaaccattga taattacctt tccggcgctg gtaaccaccc ttcacgactc
    13681 aatgcgaccg cttacctcac caaaaccagt aaatattgct cgggtagcaa attacccccc
    13741 agacgaggta attcatcaat cgtttccaaa agcaacaatt atctctttta caaatttata
    13801 tcaggcatta gcatccgtat cagccggaca gaatgattac tttattggta gtaacatcat
    13861 taccagcagt atgatttccc gctatttcac tcactcctta aatgtagtga aatattataa
    13921 ctcgccgcgt caatataatt ttttcttgac cagaaaagaa tccgtcattc ttaatgaagt
    13981 actcaataga tttgttgatg ctttaacaaa tgaagttcgc tatgaagttt cacaaaattg
    14041 gcttgataca ggaaacctgg cctttctgaa caaaccatta gaactcactg aacatgaaaa
    14101 acagtggatt aagcaacatc ccgatttaaa ggtgctggaa aatccttact ctcctcccta
    14161 ttctatgacg gatgaaaatg gctcggttcg gggcgttatg ggggatattc ttaatattat
    14221 taccttgcaa acaggtttaa atttttctcc gatcaccgtt tcacacaata tccatgccgg
    14281 aacacagctt aaccccggtg gatgggatat aatacctggc gctatttata gtgaagatcg
    14341 agaaaataat gtttcatttg cagaagcttt cataacaacg ccatacgttt ttgtcatgca
    14401 aaaagcacct gacagtgaac aaacattaaa aaaaggaatg aaagttgcca ttccatatta
    14461 ttatgagctg cattcgcaat taaaagagat gtatccggag gttgaatgga tacaggtcga
    14521 taatgccagc gctgcatttc acaaggttaa ggaaggtgaa cttgatgctc tggtcgcgac
    14581 acagttaaat tcgcgttaca tgatcgatca ttactatcct aatgaacttt atcattttct
    14641 tattcctggc gttccgaatg catcgctttc gttcgctttt cctcgcggag aaccggaact
    14701 taaggatatt attaataaag cactgaatgc aattccccca agcgaagttc tgcgcctgac
    14761 ggaaaaatgg attaaaatgc ccaatgtgac cattgacaca tgggacctat atagcgagca
    14821 attttatatt gttacgacat tatccgtttt attagttggc agtagccttt tatggggatt
    14881 ctacctgtta cgctcagttc gtcgtcgtaa agtcattcag ggtgatttag aaaaccaaat
    14941 atcattccga aaagcactct cggattcctt accgaatcca acttatgttg taaactggca
    15001 aggtaatgtc attagtcata atagtgcttt tgaacattat ttcactgcgg attactacaa
    15061 aaatgcaatg ttaccattag aaaacagtga ctcacccttt aaagatgttt tttctaatgc
    15121 gcatgaagtc acagcagaga cgaaagaaaa tcgaacaata tacacacagg tatttgaaat
    15181 tgataatggc atcgagaaaa gatgcattaa tcactggcat acattatgca atcttcctgc
    15241 aagtgacaat gcagtatata tttgtggttg gcaagatatt actgaaacgc gtgatctaat
    15301 taatgcactc gaggtagaaa aaaataaagc gataaaggct accgtagcaa aaagtcagtt
    15361 tctggcaacg atgagtcacg aaataagaac accaataagc tctattatgg gcttcctgga
    15421 acttctgtcg ggttctggtc ttagcaagga gcaacgggtg gaggcgattt cacttgccta
    15481 cgccaccgga caatcactcc tcggcttaat tggtgaaatc cttgatgtcg acaaaattga
    15541 atcgggtaac tatcaacttc aaccacaatg ggtcgatatc cctactttag tccagaacac
    15601 ttgtcactct ttcggtgcga ttgctgcaag caaatcgatc gcattaagtt gcagcagtac
    15661 atttcctgat cattacctgg ttaagatcga ccctcaggcg tttaagcagg tcttatcaaa
    15721 tttactgagc aatgctctca aatttaccac cgagggggca gtaaaaatta cgacctccct
    15781 ggttcacatt gatgacaacc acgctgttat caaaatgacg attatggatt ctggaagtgg
    15841 attatcgcag gaagaacaac aacaactctt taaacgctac agccaaacaa gtgcaggtcg
    15901 ccagcaaaca ggatctggct taggcttaat gatctgcaaa gaattaatta aaaatatgca
    15961 gggcgatttg tcattagaaa gtcatccagg cataggaaca acatttacga tcacaatccc
    16021 ggtagaaatt agccagcaag tggcgactgt cgaggcaaaa gcagaacacc ccatcacact
    16081 acctgaaaag ttgagcatat taatcgcgga tgatcatccg accaacaggc tattactcaa
    16141 acgccagcta aatctattag gatatgatgt tgatgaagcc actgatggtg tgcaagcgct
    16201 acacaaagtc agtatgcaac attatgatct gcttattact gacgttaata tgccgaatat
    16261 ggatggtttt gagttgactc gcaaactccg tgagcaaaat tcttccttac ccatctgggg
    16321 gcttacagcc aacgcacagg ctaacgaacg tgaaaaaggg ttaagttgcg gcatgaactt
    16381 atgtttgttc aaaccgttga ccctggatgt actgaaaaca catttaagtc agttacacca
    16441 ggttgcgcat attgcacctc agtatcgcca ccttgatatc gaagccctga aaaataatac
    16501 ggcgaacgat ctacaactga tgcaggagat tctcatgact ttccagcatg aaacgcataa
    16561 agatctaccc gctgcgtttc aagcactaga agctggcgat aacagaactt tccatcagtg
    16621 tattcatcgc atccacggtg cggctaacat cctgaatttg caaaagttga ttaatattag
    16681 ccatcagtta gaaataacac ctgtttcaga tgacagtaag cctgaaattc ttcagttgct
    16741 gaactctgta aaagaacaca ttgcagagct ggaccaggag attgctgttt tctgtcagaa
    16801 aaatgactaa atagcggctc ccacaatgtt caaatgtggg agctatttac cagcacatct
    16861 tacatttatg atgagaactc ctggcgaatt tgttccccat gctggtcgag cgttgccgct
    16921 cccggcataa catgcgggtc cgcgcagccg ctgattttta tcggattacc cggcatcatt
    16981 attcccccgg cttcaatcaa catatttctc gcctgagttt gtggcaattt aatggcctca
    17041 gccacactta ataacggcgc gacgggtaca ccaacttcat gtattctggc taaccaaact
    17101 tcagctgcct gcgtttttaa cgtccgctca atatattgtt taagaatagc ctggttttgt
    17161 acgcgtaaaa tattgctgct aaatcgggga tcattaacca gttccgtaag ctccagtgcc
    17221 tggcataacg cagaaaaaag cttgtcatta ccacaacaaa tcgtaatcgg cttatcctga
    17281 gtattgaaaa catcaaaagg tgccatgtag ggatggcgat ttcccagacg ttgtggtgac
    17341 ttcccagttg cgatatatgc catcagacca tgctccagaa aactcagcgt ggcatcaaac
    17401 atcgctatat cgacatgcgc ccctctctgg ctcttttcgc ggccataaag tgcactcact
    17461 attccgctga ataaatagac accgccgcat agatccgcaa gagaggtacc aacgcgcact
    17521 ggcggagcat caggatatcc tgtttccatc attatcccgc tcattgcctg aatgatggta
    17581 tcgtaggcag gagcatcttt tagcggaccg gtatgtccga aacctgacga tgaagcatat
    17641 atgaggcgcg ggttgatttc ttgaagcgtt tcccatgaaa accccagttt ttccattgta
    17701 cctgggcgaa aattctcagc taatacatca gcttgtttga gcatatttat aaatatactt
    17761 ttatcgtgat cattctttaa atcaagaacc acactctctt tgccatgatt aataaaactg
    17821 taatagagtg actgtccatc cacataggga ccaaatgtgc gggtatcatc accatgaccc
    17881 ggcggctcaa ctttaattac ccttgcgccc atattacaaa gaagttgagt tccgaaaggt
    17941 ccattaagga catgtgtcat atcgataact aataagcctt caaacggccc tttgctttca
    18001 ttatttgtca tttgcttatg ccttgaaaaa agccgaaggt gaaaagacac ttcggcattt
    18061 atgtaaaatc aataacatga ttaattatga aaccagtcga ctgacataaa tccacaaggg
    18121 agccgtgacg acaaagccca gtacgctcac agccaatgac gctgtaccag tacgggtgta
    18181 gacattaaac cggctggcaa taatgattcc ggagaatgcc ggcggtaatg cgcctgccag
    18241 taccatcatc tgcagatgtt cgctgttcaa atgacatgcc ataccaacga gaagcagtgc
    18301 cagtggcatc agaatcagct tcaggaaggt gttataagca atttcggcac tgaactcgaa
    18361 tttatgtgca gccagagtca accccgcagc gaataccgct acccctgagt tagccttcgc
    18421 aatcagatta aaggttgggt cccatgctgc cggaattttt accccaacca acaccaggat
    18481 cgttgccaga acaggtgccc atactactgg ctcctttgcc gcagaaatta atgcgctcag
    18541 attactattc ttcttaccat ccgctcctga ggaaggattc agcaaataca gaccaatagg
    18601 aatagtaatt gcgttaacaa taatagaaat aattgctacc actaaacctg ttgatacgga
    18661 atcaccataa ataggatcga gaactgcaaa ccccaggaat ccaatggtag gtgaacccgc
    18721 aattaatgca catacagctg cttctgcatg ggtacgttta aaaaatttgt agcaaccaaa
    18781 ccaggagaaa aagaaacatc cgacaataac cacaagtgat acaagggtca gacgagtgtc
    18841 cgcaaaaatc atttccctgt ttgcccgggt aatagaaaca aatagagccg caggaagagc
    18901 gtagtttaat accagtttat taaatgcgcg ggcttgatct tctgaaaaag tttctcgtct
    18961 gccgctaaaa taacccaaca gcatgattac gataataggc aataaatcgc caataaaaaa
    19021 tgttagcata atagtatttc cgataagggt cccctcacca tcgcataatg agttggcaag
    19081 aggagacgat gtcagtattt aattaccagc gacttgtttt gggttaagtt tggtaatatg
    19141 gccactttca gttcctgctg cagggtcgat gaccacatta ataatggtcg gtttgcgcga
    19201 ctgaataccg gtggttaaag catgacgaag ttcatctgtc gtggtgacgt tatagccaac
    19261 gccacgaaac gcatccatta atttgtcata ccttgcatgg tgcaacagat ccgttggtga
    19321 tggtgcacca gcgccactga gatcaacacc gtctcctctg tagatgccgc cattattaaa
    19381 aataacgatc gtcaccggca ggttatatcg acaaatcgtt tcaatttcca tcccactgaa
    19441 accaaaagca ctatcacctt caatggcgac aaccggagaa ccagaagtca cgctagcacc
    19501 gatggcatag cccataccga tgcccatgac accccaggta ccacaatcca gacgacgacg
    19561 tggtttatac atatcaataa tatttcgtgc attatccagg gtatttgcac cttcattaac
    19621 taaataaata tcctggttct cgcgcaatac gtcgcgcaca gcacttaatg cattaaagta
    19681 atttaatggt tgagtatctg tacttaattt ttcatgcatt ttttgtgcat tttgctgctt
    19741 gtggatattt aaaatatcgc gccataccag tggagtcgta aatgtgtttt gtttcagttc
    19801 tgccagcata ccttgcatac tggatgcaat atcaccaacg actggcacag caatggggcg
    19861 gttgctgtca atttcctgcg gttcaatatc cagttgaata aactgtgtat ctgccgccca
    19921 tcctttttta ccgtgtgcca ataaccaatt cagtcgtgca ccaacaagca tgacaacgtc
    19981 agcatttgcc agggcaaacg aacgcgcagc tgccgcagaa agtggatgcg tatcttcaag
    20041 gatccctttc gccatagaca ttggcaggaa tggaatctga gtactttcaa taaattcacg
    20101 aagctgttca tcagcttgtg aatacgccgc gcctttgcca aggataatta atggccgttc
    20161 agcttttgct aaaagcgaaa ttgcgctagt gactgacttc gggcatggca ataatgctgg
    20221 cgacggattt tcaactttaa caatcgtggt taacgcttcg tctttttcca tcgtcgcggc
    20281 caggacattt gctggcaaat caagataaac tccgccaggg cgacccgata cagagacccg
    20341 gatagcgcgt gccaatgcaa tgccaagatc ctgcggctga ttaacgcgaa atgctgcttt
    20401 ggcatacggt tttgccgcat tcatttggtc cagctcttca taatcacctt gctgtaggtc
    20461 gacgatcgcg cggtcgctgg agccgctaat catgatcatc ggaaaaccat ttaccgttgc
    20521 gttggccaat gcggtcaaac cattgaggaa tcctggcgca gaaactgtca ggcagatccc
    20581 cggtttttgg gtaagaaaac cgcttgccgc agcggcatag cctgccgact gctcatgacg
    20641 aaaaccaata taacgaatgc cttccgcctg ggcatggcgt gccatatccg tcacaggaat
    20701 acctacaaca ccataaatag tgtcaatatt attctgtttt aatgcttcaa cgatgatatg
    20761 cataccatct gtcatttgaa gttgatctga catgattaat aacctcgaaa tttttataaa
    20821 ttgggagcca gaagcccccg ttaatatcag atggcgtggt tttgcttcat tgcagcaatt
    20881 tcatcgtcgc tataacccag ctcctgcaat acagcagcgg tatgttcacc taatagcggc
    20941 gcagctttaa tatccggcgt aaaggcagag aatttcattg gacaaccaac ggtcagatat
    21001 tttccacgca acggttgttc cacttcaaca acactgccac tttggcgcaa agagggatca
    21061 agtgaaattt ctttcatact taaaaccggt gcacaaggaa tatcaaactg agtcaaatag
    21121 gccaccgctt catgtttatc aatagtgaca gtgtattttt cgatttcagc aaaaatatcg
    21181 aaaatatgtg gctgtcgtgc atgggctgta ctgtatgccg gatcggtaat ccattctggt
    21241 ttgccgatgg ctttacaggt gttttcccag ttttgctcct gaatagtgaa ataaatatag
    21301 gcgttaggat cggtttccca gcctttacat ttcaggatcc agccaggctg accgccacca
    21361 cctgcattac caccgcgggg aactgcatca ccaaatgtac cattcggata ctgcgggtat
    21421 tcttccagat aacccaattt atcgagacgc tgctggtcac gtaatttcac gcggcaaagg
    21481 ttcaatacgg catcctgcat tgacatggtg actcgttgcc cacgccccgt tttttcgcga
    21541 tgcagcaaag cagcaagtaa accgatcagc aaatgcattc cggtgttgct gtcacccaac
    21601 gctgcagcgc ttaccagcgg cggaccatcc caaaaacccg tagtggatgc cgcgccaccc
    21661 gctgcctgag caacgttttc ataggctttt acattcacat aaggcgaaca ctcatcaaac
    21721 cctttgatcg aaccaaaaat cagacgtgga ttgatttctt gaatatgctc ccaggtgaag
    21781 cccatgtgat caatggcccc tggatgaaag ttctcgacta agatatcagc ttcgcggatc
    21841 agcttttcca ttacctcttt gccttccgct gttttggtat ttaactcaat agaacgtttg
    21901 ttactgttaa gcatggtgaa gtaaagcgca tcgatatcag gaatatctcg cagctggtga
    21961 cgcgttacgt caccaacgcc gggacgttca attttaataa cgtcagcgcc aaaccaggcc
    22021 agcatttgag tacaagatgg gccagattgc acaccggtga aatcgagaac tttaattcct
    22081 tgaagtggag ttgacatagc aatacctatt agttaattaa atatgtgtta atttagcgtt
    22141 tatttaaggc gtaatatctt ctataaataa cccgcaaaat atcgtcgtag ctgcactcga
    22201 tatttttaaa atcctgtatc aagtgctgaa aatcatttca tcgccacttc caattccttt
    22261 ctgcatggta agtagtgagg acgaaaagaa gaatatgata aatattgatt cgtggtaatc
    22321 agagagagtc gcgacatttg tgatgttatt cttacaactg taagaagcgc cggtgattta
    22381 caagtaaggg tatgattacg ctttttaaag cgtaccataa aacataacat aataaatgat
    22441 ttgtgatgac acgggattat tgggatttac tttgaggaag ataaaatgcg tgtttataga
    22501 atcgcgagcg ccaaataatt ttatgaccac aacctgtcgt attgtggtca taaaaaattg
    22561 tcggctggag ggagttaaat cctttacctc aatatactgc ctgtcagcat tagttcacaa
    22621 acagtgcttc gctgtcgacg atgattccat cttccgcacc tttaagcgcc aggtttgcct
    22681 cgtagtattg ctttttatca agcagtttct gcgcatcagc aagtgcatta cgagtctgtt
    22741 taagcggcat cagatattgg ttttccatta cgccaacacc ggccaggcga agttcttcca
    22801 ttgcgccctt tttatcccct ttcgccattt tttcattggc aatttttatc gcggcttctt
    22861 tttcgggagt tgctacataa ctctcagaaa ttccgacaga tgcattaatg acaatatatt
    22921 ggtcatcatt gagattggtc tttttacctg gcttagcgaa ctttgcccat tcggtactgt
    22981 catctgacag caaagcggaa gcttcattgg tcagttcttt tgccttttct ggatcgccat
    23041 gaaacagagc caggcgcgct acctgcacgt cacgcatcgc atataaacct tgttcagaga
    23101 tacgctctgc tgctgccgtt ttctgggttt gctgaacttg ctgagtttgc tgttgtgccg
    23161 ctaccggtgc attatcagca gcccatacag ttgaagatgc cagaattgct gtgaccatcg
    23221 tagccataat taaacgtttc atacttacct cattctttaa cagttttaga aaacgccgcc
    23281 atcatattgg gtgagcatga aatgagaaat cagagagcaa cggtcatttt gaaagggtta
    23341 tcttacagtt gtagttatta tcgcaagaag tattttagtc ttacaattgt aggaatctgc
    23401 ttcctgtcgc agagaactat tctta
//
LOCUS       DAZUDJ010000073        22463 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.073, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000073 DAZUDJ010000000
VERSION     DAZUDJ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22463
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.073"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..66
                     /locus_tag="ACHY1N_003891"
     CDS             <1..66
                     /locus_tag="ACHY1N_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046103.1"
                     /translation="LVDTSSAPDIEWPTPPAVQAR"
     gene            complement(38..631)
                     /locus_tag="ACHY1N_003892"
     CDS             complement(38..631)
                     /locus_tag="ACHY1N_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0098004 - virus tail fiber assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HFS4046104.1"
                     /translation="MKPVFDENGLATVPGDMRCFYYDAETSEYTGWSDEYINTGVSMP
                     ACSTGIDPGENIPGKVAVFTGKGWSHEEDHRNETVYSTENGAAVTVDYIGAIKDGYVT
                     LSPLTPYDKWDGEKWVTDTEAQHSAAVDAAEAQRQSLIDTVMASISLIQLKLQAGRKL
                     TQAETTRLNAVLDYIDAVTVTDTSTAPDIIWPELPEA"
     gene            complement(631..1377)
                     /locus_tag="ACHY1N_003893"
     CDS             complement(631..1377)
                     /locus_tag="ACHY1N_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFS4046105.1"
                     /translation="MHRIDTKTAQKDKFGAGKNGFTRGNPQTGTPATDLDDDYFDMLQ
                     EELCSVVEASGASLEKGRHDQLLTALRALLLSRKNPFGDIKSDGTVKTALENLGLGEG
                     SPAIGVPFFWPSAAMPNTVIDSWSSMVFLKFNGAKFSATDYPVLAKVFPSLVLPEARG
                     DFIRIWDDGRGADGGRELLSWQAATNFSQFAGNIGEGAGHAINFHDGIAGNQPGFSRF
                     NFTSNSVGDGVNFVAVRPRNIALNFLVRAK"
     gene            complement(1381..1965)
                     /gene="ymfQ"
                     /locus_tag="ACHY1N_003894"
     CDS             complement(1381..1965)
                     /gene="ymfQ"
                     /locus_tag="ACHY1N_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HFS4046106.1"
                     /translation="MDVTNDDYIRLLSALLPPGPAWSASDPAIAGAAPSLTRVHQRAD
                     ALMRELDPRTTTELINRWERLCGLPDECIPAGTQTLRQRQQRLDAKVNLSGGINEDFY
                     LAQLAALGRPDATITRYDKSTFTCSSACTDAVNAPEWRYYWQVNMPAATNTTWMTCGD
                     PCDSALRIWGDTVVECVLNKLCPSHTYVIFKYPE"
     gene            complement(1956..3014)
                     /locus_tag="ACHY1N_003895"
     CDS             complement(1956..3014)
                     /locus_tag="ACHY1N_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFS4046107.1"
                     /translation="MADSEFQRPTLAENISMLRNDLFARLDVSDTLRRMDEDVRAKVY
                     AAALHTVYGYIDYLAMNMLPDLCDESWLARHAAMKRCPRKGATAASGYMRWEGVSDGL
                     KVTAGSVIQRDDLVQYTATADATSSGGVLRVPITCSTTGAVGNADDGTALILVTPVNG
                     LPSSGVADTLTGGFDTEDLETWRARVIERYYWTPQGGADGDYVVWAKEVPGITRAWTY
                     RHWMGTGTVGVMIASSDLINPIPEESTETAARQHIGPLAPVAGSDLYVFRPVAHKVDF
                     HIRVTPDTPEIRAAITAELRSFLLRDGYPQGELKVSRISEAISGANGEYSHQLLAPAD
                     NISIAKNELAVLGTISWT"
     gene            complement(3001..3426)
                     /locus_tag="ACHY1N_003896"
     CDS             complement(3001..3426)
                     /locus_tag="ACHY1N_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage GP46 family protein"
                     /protein_id="HFS4046108.1"
                     /translation="MELWLTVNGKRTCASAPLDPLTRAVVISLFTWRRAEPDDNADVP
                     MGWWGDTWPAVQNDRYGSRLWLLQRSKLTNQLVQTVRGYIRECLQWMTDDGVVSRIDL
                     DIRRTGINELGNSITLWRRDGPVMISFDDLWSAITHGGQ"
     gene            complement(3426..3974)
                     /locus_tag="ACHY1N_003897"
     CDS             complement(3426..3974)
                     /locus_tag="ACHY1N_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015364403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HFS4046109.1"
                     /translation="MRTIETMQRQLLGLIGRAVVKSISAATKCQTVDVSLIAGEPKAG
                     VEHLEPYGFTARANSGAEAVVLFPDGDRSHAVVVTVSDRRYRLKGLQTGEVAVYDDQG
                     QSVTLTREGIVVDGAGKTITFRNAPRARFEMDLEVTGQVKDLCDSGGTTMSAMRLAYN
                     GHRHRENGQGSNTDKPDKAMEA"
     gene            complement(3974..5053)
                     /locus_tag="ACHY1N_003898"
     CDS             complement(3974..5053)
                     /locus_tag="ACHY1N_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein"
                     /protein_id="HFS4046110.1"
                     /translation="MNDNVTLRVNGREWNGWTSVRIGAGIERLARDFSVEITRQWPGD
                     EGITTLQPRIKNGSKVEVLIGDELVITGWVEATPVRYDARSVSTGIAGRSLTADLIDC
                     AAEPTQFNGRSLVQIAQALAAPFGIEVVNSGAPSGVIPDVQPDHGETVIEVINKILGQ
                     QQALAYDDPHGRLVIGGIGSTRAHTALVLGENILSCDTEKSIRERFSVYQVAGQRAGN
                     DDDFGEATTTALRARTEDAFIARYRPMYIRQTGQATGAGCIARADFEARQRAARTDET
                     TYVVQGWRQGNGTLWQPNQRVIVFDPVCGFDNTELLVSEVTFTQDQNGTLTEIRVGPP
                     DAYLPEPEAPGARKKKKARVQEDPF"
     gene            complement(5050..6378)
                     /locus_tag="ACHY1N_003899"
     CDS             complement(5050..6378)
                     /locus_tag="ACHY1N_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA circularization N-terminal domain-containing
                     protein"
                     /protein_id="HFS4046111.1"
                     /translation="MTWKDRLQDASFRGVPFKVEEESAGTGRRVETHEYPNRDKPYTE
                     DLGKITFRPSITAYVVGDDCFDQRDRLIDALNKPGPGTLVHPTYGELKVCVDGEVRVS
                     TSKSEGRIVRFDLKFVEAGELSYPTSGAATAQTLMSSCSALDDCISDSFSGFSIDGVA
                     DFVQNDVVGNAGTMLGYVSDAMKVVDSAVSDAARLLQGDISVLLPPPSSGKNFVEQVQ
                     KMWRTGKRLYGNSSDLVTMIKTLSGVSLGSDLQPRGVWKTDSKTTATATQQRNVVASI
                     LRTTAISEAAYAVTRLPAPTTSAVMQNAAVGQATTPAQSTGWPSVTHPALNNAPAVKN
                     TVDLPTWEELTDIRDTLNTAIDKELSRTTSDALFLALRRVKADLNADINTRLEQSARI
                     IQRTPDEVLPALVLAATWFDNAARDADIIRRNAITHPGFVPVIPLKVPVQ"
     gene            complement(6439..8274)
                     /locus_tag="ACHY1N_003900"
     CDS             complement(6439..8274)
                     /locus_tag="ACHY1N_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4046112.1"
                     /translation="MAEFELKALITGVDRLSPALSKMQKKIRGFKRQAEEASQGGLAL
                     GGGLAAGLTLSLKSYADQENAATGLKVAMMDANGEVGKRFQDINKLAIGLGNQLPGTT
                     ADFQNMMQMLVRQGIPAENILGGVGKATAYLAVQLKKTPEAAAEFAAKMQDATGTASE
                     DMMGLFDTIQKAFYLGVDDTNMLSFFTKTSSVLKMVNKDGLQAAQSLAPISVMMDQMG
                     MNGESAGNALRKVIQSGLSVKKIRDVNKIMARQKLGVQLDFTDGKGSFGGLDNMFRQL
                     AKLRKLTDVKRTGVLKAIFGDDAETLQVVNALIDKGKDGYDQIQQKMNKQASLNKRVQ
                     AQLGTLSNLWEAMTGTATNGLAAIGGAFSGDAKNITQWLGELGEKFTKFADENPRVIR
                     GVVGLAAGLAILKLGLMGVGSAISIVSRLMSMTPIGMIATAIALAAGLIITNWDVVGP
                     YFKKLWETIGPYFETGWELLKKVFAWSPLGMVINNWGPVVKWFQDMWDKLKPIIEWFT
                     DSSGDTVDAINSAQWGAGAYDAYGTGIPARGYTPYPAVDPAQSNNASDATGPNPFMIN
                     KASAPKVDGEIKVSFVNSPPGMRVMETRSSGFDVSHDVGYTRFGR"
     gene            complement(8416..8685)
                     /locus_tag="ACHY1N_003901"
     CDS             complement(8416..8685)
                     /locus_tag="ACHY1N_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0098003 - viral tail assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HFS4046113.1"
                     /translation="MKELELKKPITAHGETLSVLEFDEPTGKDVRELGYPYQMNQDES
                     VRLLAHVVSKYIVRLAKVPQSSVDQMSPADLNAAAWLVAGFFLQA"
     gene            complement(8685..9041)
                     /locus_tag="ACHY1N_003902"
     CDS             complement(8685..9041)
                     /locus_tag="ACHY1N_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFS4046114.1"
                     /translation="MARIGGTCYFKIDGQQLSLTGGIEVPMNRMVNDDIIGLDGSVDR
                     KETHRAPYVKGTFKVPKNFPVGKITSSDEMTITAELANGQVYVLSSAWLHGEANHNAE
                     EGTVDLEFHGEEGDYQ"
     gene            complement(9041..10537)
                     /locus_tag="ACHY1N_003903"
     CDS             complement(9041..10537)
                     /locus_tag="ACHY1N_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HFS4046115.1"
                     /translation="MTISFNTIPSNTLVPIFYAEMDNQAANTAQDSGASLLIGHANNG
                     AEIVANSLVLMPSADYARQICGAGSQLARMVEAYRQTDPFGELYVIAVPESTGAAATV
                     TLTVTGAATETGTVNVYVGRTRVQAPVTNGDNVTTIASSIKDAINAVPALPFTASSSA
                     GVVTLTARHKGLCGNEIPVSLNYYGFGGGEVLPAGVQIAVATGTAGTGAPVLTGAVAA
                     MADEPFDYIGLPFNDTASVNTLVTEMNDTSGRWSYARQLYGHVYTAKIGTLSELVTAG
                     DQFNQQHITLAGYEKDTQTPADELAASRTARAAVFIRNDPARPTQTGELVGMLSAPKG
                     KRFTMTEQQTLLSHGVATAYVESGVLRIQRDVTTYRKNAYGVADNSYLDSETLHTSAY
                     VLRKLKSVITSKYGRHKLASDGTRFGPGQAIVTPAVIKGELLATYRQLERAGIVENYE
                     LFKQYLVVERDASDPNRLNTLFPPDYVNQLRVFAVVNQFRLQYSEESA"
     gene            complement(10521..10691)
                     /locus_tag="ACHY1N_003904"
     CDS             complement(10521..10691)
                     /locus_tag="ACHY1N_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000497758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2635 domain-containing protein"
                     /protein_id="HFS4046116.1"
                     /translation="MFVKPVKGRSVPDPARGDLLPAEGRNVDENNYWLRREAAGDIRR
                     VNEKVNTDDDKL"
     gene            complement(10700..11260)
                     /locus_tag="ACHY1N_003905"
     CDS             complement(10700..11260)
                     /locus_tag="ACHY1N_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046117.1"
                     /translation="MKLTPVIAALRARCPYFENRVAGAAQFKNLPEVGKLKLPAAYVV
                     PGDDSPGENKSQTDYWQELKEGFSVVVILSNGRDERGQFASYDVVDDVRQMLFKALLG
                     WNPEACGNPITYDGGTLLDLNRHELIYQFDFSVISELTEDDTRQQDDLNSLDELRTLA
                     IDVDYLDPGNGPDGDIEHHTEITLPS"
     gene            complement(11257..11763)
                     /locus_tag="ACHY1N_003906"
     CDS             complement(11257..11763)
                     /locus_tag="ACHY1N_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001501060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046118.1"
                     /translation="MTTSFLHVDFQQPAEMRFNRARVRRAFVTIGQRHMRDARRLVMR
                     RARSAPGENPGYQTGRLARSIGYMVPRASKHRPGFMARIAPNQRNGEGNRRITGDFYP
                     AFLFYGVRRGAKRRRGHHRGASGGSGWRLAPRNNFMVETLEKNRSWTRYFLARELRKS
                     LKPERRHR"
     gene            complement(11738..12148)
                     /locus_tag="ACHY1N_003907"
     CDS             complement(11738..12148)
                     /locus_tag="ACHY1N_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFS4046119.1"
                     /translation="MKIRQAQTSATYILPDPGELNKRVLIRQRVDMPADNFGVEPQYP
                     VTFRTWAKVIQTSATTWQETAQTGDAITHYITIRYRRGITADYEVVCGDSVYRVKRQR
                     DLNGARRFLLLECTELGECRQSHGGNNDDFLFAR"
     gene            complement(12145..12468)
                     /locus_tag="ACHY1N_003908"
     CDS             complement(12145..12468)
                     /locus_tag="ACHY1N_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001492759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFS4046120.1"
                     /translation="MLLTMEEIKAQLRLDEDFDADDRHLQLLACAAQKRTETYLNRKL
                     YAPDETIPDSDPDGLHLPDDIRLGMLMLISHFYENRSSVTDVEKMELPMSFNWLVGPY
                     RYFPQ"
     gene            complement(12471..12671)
                     /locus_tag="ACHY1N_003909"
     CDS             complement(12471..12671)
                     /locus_tag="ACHY1N_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001735262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046121.1"
                     /translation="MILKQDLKWSPDGMRVEVIRAGEYDDGALPARVQEIALQAGLAE
                     RGTSAKSSKATKEKKATTSKEG"
     gene            complement(12721..13926)
                     /locus_tag="ACHY1N_003910"
     CDS             complement(12721..13926)
                     /locus_tag="ACHY1N_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFS4046122.1"
                     /translation="MAVDIKDVEQVAQELQQKFDDFKAKNDKRVDAIEQEKGKLAGQV
                     ETLNGKLSELENLKSDLEKELLELKRPAGGAQNKLATEHKEAFVGFLRKGREDGLRDL
                     ERKALQVGTDEDGGYAVPEELDRNILNLLKDEVVMRQEATVITVGGSDYKKLVNLGGT
                     ASGWVGETDTRSQTATSRLELIEPLMGEIYGNPQATQKMLDDAFFNVEAWINSELATE
                     FAEQEEIAFTSGDGTKKPKGFLAYESTDETDKVRAFGKLQHIVSGEATAVTADAIIKL
                     IYTLRKAHRTGAKFMMNNNSLFAIRLLKDTEGNYLWRPGLELGQPSSLAGYGIAENEQ
                     MPDIAADAKAIAFGNFKRGYTIVDRIGTRILRDPYTNKPFVGFYTTKRTGGMLVDSQA
                     IKLLKIAAA"
     gene            complement(13941..14591)
                     /locus_tag="ACHY1N_003911"
     CDS             complement(13941..14591)
                     /locus_tag="ACHY1N_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFS4046123.1"
                     /translation="MQTKQRLDVPLSLKSVSDSGEFEGYGSVFGVKDSHDDVVMSGAF
                     AASLRAWSDRKALPALLWQHRMDEPIGVYTEMKEDDVGLYVRGRLLIDDDPLAKRAHA
                     HMKAGSLTGLSIGYVLKDWEYDRSKEAFLLKEIDLWEVSLVTFPSNDEARISDVKNAL
                     ARGEIPEQKKIERVLRDVGLSRTQAKAFMAGGYGALSLRDAEDVGSALNALKNLNF"
     gene            complement(14569..15810)
                     /locus_tag="ACHY1N_003912"
     CDS             complement(14569..15810)
                     /locus_tag="ACHY1N_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4046124.1"
                     /translation="MFFSGLFQRKSDAPVTTPAELADAIGLSYDTYTGKQISSQRAMR
                     LTAVFSCVRVLAESVGMLPCNLYHLNGSLKQRATGERLHKLISTHPNGYMTPQEFWEL
                     VVTCLCLRGNFYAYKVKAFGEVAELLPVDPGCVEPKLNSSWEPIYQVTFPDGSTDVLS
                     QEDIWHVRTLTLDGLVGLNPIAYAREAISLAAATEEHGARLFSNGAVTSGVLRTEQTL
                     SDQAYERLKKDFEERHTGLGNAHRPMILEMGLDWKSMALNAEDSQFLETRKFQLEEIC
                     RLFRVPLHMVQNTDRATFNNIEELGLGFINYSLVPYLTRIEQRINTGLVRKSKQGVYY
                     AKFNAGALLRGDMKSRFEAYATGINWGIYSPNDCRDLEDMNPRPGGDVYLTPMNMTTK
                     PSDGSKAGKQKDNANADETTS"
     gene            complement(15810..15992)
                     /gene="ymfR"
                     /locus_tag="ACHY1N_003913"
     CDS             complement(15810..15992)
                     /gene="ymfR"
                     /locus_tag="ACHY1N_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmfR"
                     /protein_id="HFS4046125.1"
                     /translation="MIMLILAPLVGVLGALLLAYGAWLIYPPAGFVVAGALCLFWSWL
                     VARYLDRTQLSVGGGK"
     gene            complement(16004..17737)
                     /locus_tag="ACHY1N_003914"
     CDS             complement(16004..17737)
                     /locus_tag="ACHY1N_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HFS4046126.1"
                     /translation="MSRKSYPNVNAANQYARDVVRGKIVACQFVIQACQRHLDDLMAE
                     KSKSFRYRFDKDLAERAAKFIQLLPHTKGEWAFKRMPITLEPWQLFVVCCAFGWVNKG
                     SRLRRFREVYTEIPRKNGKSAISAGVALYCFACDNEFGAEVYSGATTEKQAWEVFRPA
                     RLMCKRTPMLTEAFGIEVNASNINRPEDGARFEPLIGNPGDGSSPHCAVVDEYHEHAT
                     DALYTTMLTGMGARRQPLMWAITTAGYNIEGPCYDKRREVIEMLNGSVPNDELFGIIY
                     TVDEGDDWTDPQVLEKANPNIGVSVYREFLLSQQQRAKNNARLANVFKTKHLNIWVSA
                     RSAYFNLVSWQSCEDKSLTLEQFEGQPCILAFDLARKLDMNSMARLYTREIDGKTHYY
                     SVAPRFWVPYDTVYSVEKNEDRRTAERFQKWVEMGVLTVTDGAEVDYRYILEEAKAAN
                     KISPVSESPIDPFGATGLSHDLADEDLNPVTIIQNYTNMSDPMKELEAAIESGRFHHD
                     GNPIMTWCIGNVVGKTIPGNDDVVKPVKEQAENKIDGAVALIMAVGRAMLYEKEDTLS
                     DHIESYGIRSL"
     gene            complement(17734..18228)
                     /locus_tag="ACHY1N_003915"
     CDS             complement(17734..18228)
                     /locus_tag="ACHY1N_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFS4046127.1"
                     /translation="MAGTAGRSGRRPKPTARKALAGNPGKRALNKDEPVFTPIKGVEP
                     PEWFAEENLPLATIMWQLTTKELCGQGLLCVTDLAVLERWCVAYEFWRRAVKNIAIQG
                     NTITGAMGGRVKNPELTAKKEQESEMSSTGAMLGLDPSSRQRLIGLAGQKKATNPFLK
                     IIES"
     gene            complement(18354..18704)
                     /locus_tag="ACHY1N_003916"
     CDS             complement(18354..18704)
                     /locus_tag="ACHY1N_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFS4046128.1"
                     /translation="MPPRIPKACRARGCRNTTTDPSGYCESHKSEGWKQYKPGQSRHQ
                     RGYGSKWDSIRARVLKRDKGLCQLCLRSGVVREAKTVDHIIPKAHGGTDADSNLQSLC
                     WPCHKAKTARERLK"
     gene            complement(18917..19168)
                     /locus_tag="ACHY1N_003917"
     CDS             complement(18917..19168)
                     /locus_tag="ACHY1N_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046129.1"
                     /translation="MSSTKLVKTILFHGDNKYEVYATSEYADVDRIIHYKLRSCKNTD
                     GSDGKSESIWVVYNPAVQLPDDLNYKKVSNIAPYLEKLQ"
     gene            complement(19598..20035)
                     /locus_tag="ACHY1N_003918"
     CDS             complement(19598..20035)
                     /locus_tag="ACHY1N_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009453323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HFS4046130.1"
                     /translation="MSRVTAIISALVICIIVCLSWAVNHYRDNAMTYKEQRDKAASII
                     ADMQKRQRDVAELDARYTKELADANATIESLRADVSAGRKRLQVAATCAKSTTGASSM
                     GDGESPRLTADAELNYYRLRSGINRITAQVNYLQEYIRTQCLK"
     gene            complement(20032..20508)
                     /locus_tag="ACHY1N_003919"
     CDS             complement(20032..20508)
                     /locus_tag="ACHY1N_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003796 - lysozyme activity [Evidence
                     IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA];
                     GO_process: GO:0016998 - cell wall macromolecule catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="HFS4046131.1"
                     /translation="MQVLNSQRKAFLDMVAWSEGTDNGRQPTRNHGYDVIVGGELFTD
                     YSDHPRKLVTLNPKLKSTAAGRYQLLSRWWDAYRKQLGLKDFSPRSQDSVALQQIKER
                     GALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIEV"
     gene            complement(20512..20838)
                     /locus_tag="ACHY1N_003920"
     CDS             complement(20512..20838)
                     /locus_tag="ACHY1N_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin, lambda family"
                     /protein_id="HFS4046132.1"
                     /translation="MPHNPNTWLELVQSWWRGDTPLGAVIMSIVMAGLRIAYFGGGGG
                     WKRKTLEILLCGALTLTFASALEYVGWPKSLSVAIGGGVGLIGVDAIRGAAMRVIGNK
                     FGGSKE"
     gene            21130..22305
                     /locus_tag="ACHY1N_003921"
     CDS             21130..22305
                     /locus_tag="ACHY1N_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009295 - nucleoid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFS4046133.1"
                     /translation="MDITCLECGNVLDDPTVACDKCGATPHVVVLGKQSYFPIGAVTA
                     NLEKNDSRAFDYRLGEVWDLKNEVTSEFITRIEKKFSRKNKFHNFLDSDHNPSSIPTI
                     LKKYINKNNEFIDLSRAIIEKLKHNANNESRVAQLQGGSVVFIHYKSTEPEDLGKLLI
                     VMVDKQSAYDFDSDKLTPTRLNPINTDALRQAAMFDLTLFEASYPENKGDSYVHFLQG
                     KSKSDFFKDSLGCRHDSDNKRSIQQLFSAIDIFASKNSLGRVLRDTIDNEVKSLLEKK
                     SKDKHGNKSVKIEDISKIIDSCLTDSHKCKGTFVDFVNLNGFQIDPQFEPTPKAAESA
                     LTIEVADNDNNFKLKIMRGAIGDEKSNKPVILTDNKCEIVIKLSQANYDELKRYRDS"
BASE COUNT         5171 a         6448 c         5477 g         5367 t
ORIGIN      
        1 ctggtcgata cttccagtgc gccagatatt gaatggccta cgcctccggc agttcaggcc
       61 agatgatatc cggcgcggtg ctggtatctg ttaccgtcac cgcgtcaatg taatccagca
      121 cggcgttaag tcgggttgtt tctgcctgcg tcagtttccg tccggcctgc aatttcagtt
      181 gaatcagact aatggaagcc attacagtat caatcagtga ctgacgttgt gcttctgccg
      241 cgtctactgc ggcgctatgc tgtgcctcgg tatccgtcac ccatttctca ccatcccatt
      301 tatcgtatgg cgttaacggt gaaagcgtga cataaccgtc tttgatggca ccgatataat
      361 ccactgtaac agctgcgcca ttttctgttg agtaaacagt ctcattgcga tggtcttctt
      421 catggctcca tcccttaccc gtaaatactg ccacttttcc cggaatgttt tcgccagggt
      481 caataccagt ggaacaggcg ggcatactta cgccagtatt aatatattca tcagaccagc
      541 ccgtatactc agatgtttca gcatcataat aaaaacaacg catatcgccc ggcactgtag
      601 ccagcccatt ttcatcaaaa acaggtttca ttatttagcc ctcaccagaa agtttaatgc
      661 aatatttcgc ggtctgacag caacaaaatt cacaccatca cccacagagt tactggtgaa
      721 attaaatcgt gaaaatcctg gctgatttcc ggcgatgcca tcatgaaagt taattgcgtg
      781 tcccgcacct tcgcctatat tcccggcaaa ctgagaaaag tttgtagctg cctgccagct
      841 taataattca cgaccaccat ctgcacctcg cccgtcatcc cagatacgaa tgaaatcacc
      901 gcgggcttca ggtaatacca gcgaaggaaa cactttcgcc agcacaggat aatcagtggc
      961 agagaatttc gcgccgttga acttcaaaaa caccatactg gaccaactgt cgattacagt
     1021 atttggcatt gcagcggacg gccagaagaa cggaacgcca atagctggag aaccttctcc
     1081 caaaccaagg ttttcgagag ccgttttcac cgtgccatcc gatttgatat caccaaacgg
     1141 attcttgcgg cttaacagca gcgcacgaag cgcggtaagc agctggtcgt gccgcccctt
     1201 ctccaggctg gcaccggacg cctccacaac gctgcaaagc tcctcctgca acatgtcaaa
     1261 gtagtcatca tccagatcgg tggcaggcgt gccggtctgg gggttaccac gggtaaaacc
     1321 gttcttaccc gcgccgaact tatccttctg cgcggttttc gtgtctatac gatgcatgga
     1381 ttactccgga tatttaaaaa ttacgtaggt atgcgacggg cagagtttgt taagcacaca
     1441 ctcgacaacg gtgtcgcccc agatacgcag tgcggaatca cagggatcgc cacatgtcat
     1501 ccaggtggtg ttggtggcgg ctggcatgtt gacctgccag taataccgcc attcaggcgc
     1561 gttcacagcg tcagtacagg ccgatgagca ggtgaacgtg cttttgtcgt atcgcgtgat
     1621 ggtggcatct ggtctgccca aggcagcaag ctgtgcaaga taaaaatcct cgttgatgcc
     1681 acccgacagg ttaaccttcg catccagccg ttgctgacgc tggcgaaggg tctgtgtccc
     1741 tgcgggaata cattcatccg gcagaccgca cagacgctcc cagcggttta tcagttcagt
     1801 ggtagtgcgc ggatccagct cccgcatcag ggcatccgca cgctgatgaa cgcgggttaa
     1861 tgacggtgcc gcaccggcaa tcgccggatc gctggctgac cacgccggac cggggggcaa
     1921 cagtgccgac aacagacgga tgtaatcatc gtttgtcacg tccatgaaat cgtccccagt
     1981 accgccagtt cattttttgc aatggagata ttgtctgccg gtgcaagcaa ctgatggctg
     2041 tattccccgt tcgcaccgga aatcgcttca ctgatacgtg acaccttcag ttctccctgc
     2101 ggataaccat cacgcagcag gaacgaacgc aactcggcgg tgatggcagc ccgtatttcc
     2161 ggtgtgtccg gcgtcacgcg gatatgaaaa tccactttat gcgccaccgg cctgaataca
     2221 tacaaatcag agcctgccac cggggccagt ggcccgatat gttgtcttgc cgccgtttcc
     2281 gttgattctt ccggaatggg attaatcagg tcactgctgg caatcatcac accgacagtt
     2341 cccgttccca tccagtgacg gtatgtccat gcgcgggtaa tgccgggcac ttctttagcc
     2401 cagacgacat agtccccgtc agccccgccc tgcggcgtcc agtaataccg ctcaatgacg
     2461 cgggcgcgcc acgtttccag atcttcagta tcgaatcctc cagtcagggt atctgcaaca
     2521 ccggaagacg gcagaccatt caccggcgtg accaggatta atgccgtacc gtcgtcagcg
     2581 ttaccgaccg cgcctgtagt tgagcaagtg atcggcacac gcaggacacc accggagctg
     2641 gttgcatcgg cagttgccgt gtactgaacc aggtcatcgc gctgaataac actcccggca
     2701 gtcaccttca ggccatcgct gacaccttcc cagcgcatat acccgctggc agccgtggcc
     2761 cccttgcgcg gacaccgttt catcgcagca tgtcgcgcca gccaggactc atcgcacagg
     2821 tcaggcagca tattcattgc cagataatcg atgtacccgt aaaccgtatg cagcgccgcc
     2881 gcatacacct ttgcccgcac gtcttcatcc atgcgccgga gcgtgtcgct gacgtccagc
     2941 ctggcaaata aatcgttacg gagcatactg atattttctg ccagcgtcgg gcgctgaaat
     3001 tcactgtccg ccatgcgtta tcgcactcca cagatcatca aaagaaatca ttaccggtcc
     3061 gtcacgacgc cagagagtga tactgttacc cagttcatta atcccggtgc ggcggatatc
     3121 cagatcaata cgggacacca cgccgtcatc agtcatccat tgcaggcatt cgcggatata
     3181 cccccttacc gtctgcacca gctgattggt cagtttgctg cgctgaagca gccacagtcg
     3241 ggagccgtaa cggtcattct gtaccgcagg ccaggtatcc ccccaccatc ccatcgggac
     3301 gtcggcgttg tcatcaggct ccgcccgccg ccaggtaaac agggaaatca ccacggcgcg
     3361 ggtcagcgga tccagcggtg cgctggcgca ggtgcgttta ccgttcaccg tcagccacag
     3421 ttccatcatg cctccatcgc tttatcaggt ttgtcggtgt tactgccctg accgttctct
     3481 ctgtgacgat gcccgttata ggcaagccgc atcgctgaca tggtggtgcc gccggagtcg
     3541 cacaggtctt tcacctgtcc ggtcacttcc aggtccattt caaaacgtgc tctgggcgca
     3601 ttgcgaaacg tgatcgtttt acctgcaccg tccaccacga tcccctcccg ggtcagcgtc
     3661 acggactgcc cctgatcgtc atagacagcc acctcacccg tctgcagccc tttcaggcgg
     3721 tagcgccggt ccgacaccgt aacaaccacc gcatgagaac ggtcgccatc cggaaacaac
     3781 accaccgctt ccgcaccgct gtttgccctt gcggtaaaac cgtagggttc aagatgttca
     3841 accccggctt tgggttcacc ggcaatcagg gacacatcca cggtctgaca tttcgtggcg
     3901 gcactgatgc ttttcaccac ggcccgccca atcaggccga ggagttgtcg ctgcatggtt
     3961 tcaatcgtcc tcatcagaac gggtcctcct gtactctggc ttttttcttt ttccgcgcgc
     4021 cgggggcttc gggttcaggc agataagcat caggtgggcc gacacggatt tccgtcaggg
     4081 tgccgttctg gtcctgagta aacgtgactt ccgagacaag cagttcggta ttgtcgaaac
     4141 cacagaccgg atcgaagaca atcacccgct ggttgggctg ccacagcgta ccgttaccct
     4201 gtcgccagcc ctgcaccaca taggtggttt catccgtccg cgccgcccgt tgtcgggctt
     4261 caaagtcagc acgcgcaata caacctgccc ccgtggcctg ccctgtctgc ctgatataca
     4321 tcggacggta acgggcaata aatgcgtcct ctgtgcgtgc ccgcagcgcg gtggtggtgg
     4381 cctcaccgaa atcatcgtcg tttccggcac gctgccccgc cacctggtaa acagaaaacc
     4441 gctcccggat actcttctcc gtatcacagg aaaggatgtt ttccccaagt accagcgcgg
     4501 tatgtgcccg cgttgagcca ataccgccaa tcaccagcct gccgtgcggg tcgtcgtaag
     4561 ccagcgcctg ctgctgaccg agtattttgt tgatcacctc aatcaccgtt tcaccgtgat
     4621 caggctgaac atcaggaata acacccgacg gcgcaccgct gttcaccacc tcaatgccga
     4681 aaggcgcagc aagcgcctgc gcaatctgca ccagcgagcg tccgttaaac tgtgtcggtt
     4741 cggctgcaca gtcaatcagg tcagccgtca gactacgtcc ggcaataccg gtgctgaccg
     4801 aacgggcatc gtaacgaacg ggagtcgcct ccacccagcc ggtgatcacc agctcatcac
     4861 caatcagcac ttccactttt gaaccgtttt taatgcgcgg ctgaagcgtg gtgataccct
     4921 catctcccgg ccactggcga gtgatctcca cactgaaatc ccgcgccagc cgttcaatac
     4981 cggcaccgat gcgcaccgat gtccagccat tccactcccg gccatttacc cgtagcgtga
     5041 cattgtcgtt cattgcactg gcaccttcag agggatcacc ggcacaaagc cgggatgtgt
     5101 aatggcatta cgccggataa tgtccgcgtc acgcgccgcg ttatcaaacc aggtcgccgc
     5161 cagcaccagc gcgggtaaaa cctcatccgg cgtgcgctga atgatccgtg cagactgttc
     5221 aaggcgcgtg ttgatatccg cattcagatc tgctttcacc cggcgcagcg ccagaaacag
     5281 cgcatcactg gttgtacggg acaactcctt atcaattgcc gtattcagtg tgtcgcgaat
     5341 gtcagtcagt tcttcccacg tcggcaggtc aaccgtgttt ttcaccgccg gtgcattgtt
     5401 cagtgccgga tgcgtgacgg aaggccagcc agtgctctgc gcgggtgttg ttgcctgccc
     5461 cactgcggca ttctgcatca ccgcggaagt tgttggcgca ggcaatcggg tgacggcata
     5521 cgccgcttcg ctgattgcgg tcgtacgaag gatgctggca accacgttac gctgctgcgt
     5581 cgccgtggcg gtggttttac tgtccgtttt ccagacaccg cgcggttgca gatcgctgcc
     5641 gaggctgaca ccggaaagcg ttttgatcat ggtgaccagg tcgctggagt taccataaag
     5701 gcgtttcccg gtacgccaca ttttctgcac ctgctcaacg aaatttttgc ctgacgatgg
     5761 cggcggcaga agtaccgaga tatccccctg caacagcctg gcggcatccg atacggcaga
     5821 atccaccact ttcatcgcat cagaaacata ccccagcatt gtgccggcat taccgacgac
     5881 gtcgttctgc acaaaatctg ccacgccatc gatactgaaa ccactgaagc tgtcactgat
     5941 gcagtcatcc agtgcagaac aggatgacat cagcgtctgc gccgtcgccg cacctgaagt
     6001 ggggtaagag agttctcccg cttcgacaaa cttcaggtca aagcggacaa tacgcccttc
     6061 actcttcgat gtgctgaccc gaacttcccc gtcaacacag actttcagct caccgtaagt
     6121 cggatggaca agcgtgccgg gaccgggttt attcagcgcg tcaatcaggc gatcgcgctg
     6181 gtcaaagcag tcatctccca ccacataagc tgtgatggac gggcggaaag tgattttccc
     6241 caggtcttcg gtatagggtt tgtcgcggtt cgggtattcg tgcgtttcca cacgacgacc
     6301 ggttcccgca ctttcttctt caaccttaaa cggcacaccg cgaaatgacg cgtcctgaag
     6361 tctgtctttc cacgtcatat aaactccgta cataaaaaat cccaccggag tgggactcat
     6421 taacagatta atttttcatt acctgccaaa gcgcgtatag ccaacatcat ggctgacatc
     6481 aaaaccgctg gatcgcgttt ccataacccg catacccgga ggcgaattca caaaagagac
     6541 cttgatctca ccatcaactt ttggcgcaga agctttgtta atcatgaagg gattcgggcc
     6601 tgtggcatcg gaggcgttgt ttgactgagc cggatctacc gccggataag gtgtgtatcc
     6661 ccgtgccggt attcccgtcc cataagcatc ataagcaccc gccccccact gcgccgagtt
     6721 aatggcatcg accgtgtcac cggaactgtc ggtaaaccac tcaataattg gcttcagctt
     6781 gtcccacata tcctgaaacc acttaacaac cggcccccag ttattgatca ccatccccag
     6841 cggcgaccag gcaaaaactt tcttaaggag ttcccagcca gtctcaaaat aaggaccaat
     6901 ggtttcccag agtttcttaa aataaggtcc gacaacatcc cagttagtga taattaatcc
     6961 cgcagccagg gctatcgccg tcgcaatcat gccaatcggc gtcatcgaca tgagcctgct
     7021 gacaatactg atggcactgc caacgcccat caatcccagt ttcagaatcg caagaccggc
     7081 agcaagcccg acgacgccgc gaataacccg gggattttca tccgcaaact tcgtgaattt
     7141 ttcccccaac tcccccagcc attgcgtgat atttttggcg tcaccagaaa atgcgccgcc
     7201 aatagccgca aggccgttag ttgcggtccc cgtcattgcc tcccacaggt tggacagcgt
     7261 accaagctgg gcctgaacac gtttattcag gctggcctgt ttattcatct tctgctggat
     7321 ctgatcgtag ccatcctttc ctttatcgat tagtgcattg accacctgaa gggtttcggc
     7381 atcatcacca aatattgcct taagtacacc tgtccgctta acgtcggtca gttttcgcag
     7441 ctttgccagt tgcctgaaca tgttatcaag accgccaaaa cttcctttgc cgtcagtaaa
     7501 atcgagctgt accccgagtt tctggcgggc catgatttta ttgacgtccc tgattttctt
     7561 aacgcttaat ccggactgga taacttttcg cagggcatta cctgccgact ccccgttcat
     7621 ccccatctga tccatcatga cgctgatggg ggcaaggctc tgtgcagcct gaagaccgtc
     7681 cttgttcacc atcttcagaa cagaactggt tttagtgaag aaggacaaca tgttggtatc
     7741 gtcaacgccc agataaaacg ccttctggat agtgtcgaac agccccatca tgtcttctga
     7801 cgccgttccg gtagcatcct gcatctttgc agcaaactca gcagccgctt ccggtgtttt
     7861 tttcagttgt accgcaagat aagctgtcgc tttacccaca ccgccaagaa tgttttctgc
     7921 cgggatcccc tgacgcacca gcatctgcat catgttctgg aaatcagccg ttgtaccggg
     7981 aagctggtta cccaggccaa tagccagttt attgatgtcc tgaaagcgct ttccaacctc
     8041 gccattcgca tccatcatgg cgactttcag cccggtggcg gcgttttcct gatcggcata
     8101 agatttcagg gaaagcgtca gacccgctgc cagtccgcca ccaagcgcca gcccaccctg
     8161 tgacgcttct tccgcctggc gtttaaatcc ccgtattttc ttttgcattt tcgacagcgc
     8221 gggagaaagc ctgtcgacac cggtgatcaa cgccttaagc tcaaattcag ccatgtgtgc
     8281 gtttctcctg ctctatcctg tttgcctgac tgaccagcaa gggaatttca ctgatcggca
     8341 tattcagcaa ttcgaaagga ttaatgcgcc agtagctggc gcagtcaaag aagcgatcag
     8401 taaggtattc agccgtcagg cctggaggaa aaaaccagcc acaagccacg ccgctgcatt
     8461 caggtctgcc ggagacatct ggtcgacaga gctttgcggc actttcgcca gccgcacaat
     8521 atatttcgat accacatgcg ccagaagtct gacggactca tcctgattca tctggtaggg
     8581 ataccccagc tcgcggacat ctttcccggt gggctcatca aactccagta cggagagtgt
     8641 ctcgccatga gcggtaatcg gtttctttaa ctcaagctct ttcattactg gtaatcccct
     8701 tcttcaccgt ggaactcaag atcgaccgtg ccttcttcgg cattatggtt cgcttcgccg
     8761 tgcagccaag cagacgacag tacatagacc tgaccgttcg ccagctcggc agtgattgtc
     8821 atctcatcag acgaggtgat tttgcccacc ggaaaattct tcggcacctt gaaggtccct
     8881 ttgacataag gcgcacggtg agtttccttg cggtccactg aaccgtccag gccgatgatg
     8941 tcatcattaa ccatcctgtt catgggcacc tcaatgccgc cggtcagcga tagctgctga
     9001 ccgtcaattt tgaaataaca ggttcccccg atacgggcca ttatgcagac tcctctgaat
     9061 actgaagacg gaactggtta accacggcaa agacacgcaa ctggttaaca tagtcaggcg
     9121 ggaacagcgt gttcaggcgg ttcggatcgc tggcatcacg ctccacaacc aggtactgct
     9181 taaaaagttc gtagttttcc acgatccccg cacgctcaag ctgacggtag gttgccagca
     9241 gttccccttt gatcaccgcc ggggtgacaa tcgcctgacc gggaccaaag cgggtaccgt
     9301 cgctggcaag cttgtgacgc ccgtacttac tggtaatgac ggatttcagt ttgcgcagta
     9361 catacgcact ggtatgcagc gtctcgctgt cgaggtagct gttatccgca accccgtaag
     9421 cgtttttcct gtacgtggtg acatcacgct gaatgcgcag taccccgctt tcgacatacg
     9481 ccgttgccac gccatgagac agcagggtct gttgttcggt catcgtgaac cgtttcccct
     9541 tcggcgcaga cagcataccc accagctcac cggtctgcgt gggacgtgcc ggatcgttgc
     9601 ggataaacac cgctgcgcgg gcggtacggc ttgccgccag ctcgtcggca ggcgtctggg
     9661 tgtctttttc gtaccccgcc agggtaatgt gctgctggtt aaactggtca cctgcggtca
     9721 ccagttctga cagcgtgccg atctttgccg tatacacatg accatacagc tgacgcgcat
     9781 agctccagcg accgctggta tcgttcatct cggtcaccag cgtgttaacg gaggccgtgt
     9841 cgttgaacgg caggccgata taatcaaacg gctcatccgc cattgcagcc accgcgccgg
     9901 tgagaaccgg agcacccgta ccggcggtac ccgtcgccac ggcaatctgt acgcccgctg
     9961 gcagcacttc gcccccacca aagccgtagt aattgaggct gacaggaatt tcattcccgc
    10021 aaagcccctt atgacgcgcg gtcagtgtga ccacgcctgc cgaagatgaa gccgtaaacg
    10081 gcagggccgg aacggcattg atggcatctt tgatactgct ggcaatcgtc gtgacgttat
    10141 cgccgttggt caccggagcc tgcacgcggg tacgtcccac ataaacattc accgtgccgg
    10201 tttcggttgc cgcgccggtc accgtcagcg taactgttgc cgccgcgccc gtggattcag
    10261 gaacggcaat cacatacagt tcaccaaacg ggtcggtctg gcgataagcc tcgaccatac
    10321 gcgccagctg acttcccgca ccacaaatct ggcgtgcata gtctgccgat ggcatcagca
    10381 ccagactgtt ggcaacaatc tctgcaccgt tattggcatg accaatcagc agcgatgctc
    10441 cgctgtcctg tgcagtattc gccgcctggt tatccatttc cgcataaaaa atcggaacca
    10501 gcgtattcga cggaatggtg ttaaagctta tcgtcatcgg tattcacctt ttcattcacg
    10561 cgccggatat cacccgctgc ttcacggcgc agccagtagt tgttctcatc aacatttcgc
    10621 ccctcggcgg gcaaaaggtc accgcgggca gggtcaggaa ctgaccgccc tttaacaggt
    10681 ttcacaaaca tgaagattct caggaaggaa gggttatttc ggtgtgatgt tcgatatcgc
    10741 cgtcaggccc gttaccggga tcgagataat caacatcaat cgccagcgtt cgcagttcat
    10801 ccagactgtt caggtcatcc tgctggcggg tatcgtcttc agtcagctcg ctgatgaccg
    10861 aaaaatcgaa ctgataaatc agctcatgac gattcagatc cagcagcgtg ccgccgtcat
    10921 aggtaatcgg gttaccgcac gcctccgggt tccagcccag cagagcctta aagagcatct
    10981 gccggacatc gtccaccaca tcatacgagg caaactgacc gcgctcatca cgcccgttac
    11041 tcagtatgac aaccacggag aaaccctctt tcagctcctg ccagtagtcg gtctggcttt
    11101 tgttttctcc cggagaatca tcacccggta caacatatgc cgccgggagt ttcagctttc
    11161 cgacctccgg cagatttttg aactgggccg cgcctgcaac ccggttttca aaatacggac
    11221 aacgggcacg cagtgcagca ataacaggcg tcagtttcat ctgtgtcgtc gctccggctt
    11281 cagtgattta cgcaattccc gcgccagaaa atagcgtgtc cagctgcggt tcttttcaag
    11341 agtttccacc atgaagttat tacgtggagc cagtcgccag ccgctgccac cggatgcacc
    11401 acgatgatgg ccgcgacgac gctttgcccc tcgcctcacg ccatagaaca aaaaagccgg
    11461 ataaaaatca ccggtgatac ggcggtttcc ctctccatta cgctggttag gggctatacg
    11521 tgccataaaa ccagggcgat gtttactggc tctgggtacc atgtaaccaa ttgaacgagc
    11581 caggcgtccg gtctgataac cggggttttc acccggtgcc gaccgtgcac ggcgcatcac
    11641 cagccgacgg gcatcacgca tatgacgctg accaatcgtg acaaacgccc gccggacacg
    11701 ggcgcggtta aagcgcatct ccgcgggctg ctgaaaatca acgtgcaaaa aggaagtcgt
    11761 cattgttgcc tccgtgactc tgcctacatt cgcccagctc cgtacactcc agcagcagaa
    11821 agcgccgcgc cccgttcaga tcgcgctgac gtttcacccg gtacacactg tcaccgcaga
    11881 ccacctcata atcagcggtg atcccccggc ggtaacgaat ggtgatgtaa tgggtgatgg
    11941 cgtccccggt ctgcgcggtt tcctgccagg tggtggcact ggtctggata accttcgccc
    12001 atgtccggaa cgtaaccggg tattgaggct ccacgccaaa gttatccgcg ggcatatcca
    12061 cccgctggcg gatcaggacg cgtttattca gttcaccggg gtccggcaga atgtaggttg
    12121 cgctggtctg cgcctgacga attttcattg cgggaaatac ctgtacgggc cgacaagcca
    12181 gttaaagctc attggcaact ccattttctc aacgtctgta accgacgagc gattttcgta
    12241 aaaatggctg ataagcatca gcatccccag acgaatatca tccggcaggt gcagcccgtc
    12301 cggatcgctg tccggaatgg tttcatccgg agcatagagc ttccggttca gatacgtttc
    12361 cgtccgcttt tgcgccgcac aggccagcag ttgcagatgg cggtcatcag catcgaaatc
    12421 ctcatccagc cggagttggg ctttaatctc ttccattgtc agaagcatac tcagccctct
    12481 ttactggtcg tggctttttt ctcttttgtc gctttactgc tttttgcact ggttccgcgc
    12541 tctgctaacc cggcctgaag tgcaatctcc tgcacccggg caggaagcgc cccgtcgtca
    12601 tactcaccgg cccgaatgac ctcaacacgc ataccgtccg gtgaccattt cagatcttgt
    12661 ttcaggatca tgattcttca cccgtcagaa cagggggcgc ggttccgcgc ccctgagtga
    12721 ttacgccgct gcaatcttca gcagtttgat ggcctgcgaa tcgaccagca tgccgccggt
    12781 gcgcttggtg gtataaaaac cgacaaacgg tttattggtg tacggatcgc gaagaatgcg
    12841 ggtaccgata cggtcaacga tggtgtaacc ccgtttgaag ttaccaaatg caatggcttt
    12901 cgcatccgcg gcaatatccg gcatctgctc gttttcagcg ataccgtaac ccgccagaga
    12961 ggatggctgc cccagttcca gcccaggacg ccacagatag ttaccctcgg tgtctttcag
    13021 cagacggatg gcaaacaggc tgttgttgtt catcatgaac ttcgcgccag tgcggtgtgc
    13081 cttacgcagc gtgtaaatca gtttgataat ggcgtctgcg gtcaccgcgg tcgcttcgcc
    13141 ggatacaata tgctgaagtt tgccgaacgc ccggaccttg tcggtttcat cagtggattc
    13201 atacgccagg aaccctttcg gcttcttggt gccatcgcct gaggtaaagg caatttcttc
    13261 ctgttcggca aattcggttg ccagctcgct gttgatccag gcctccacgt tgaagaaggc
    13321 atcgtccagc attttctggg tagcctgcgg gttgccgtaa atttccccca tgagaggttc
    13381 aatcagctcc agtctggagg tggcagtctg ggatcgcgta tccgtttccc ccacccatcc
    13441 ggaagccgta ccgcccagat tcaccagttt tttgtagtcg gaaccgccaa cggtgatcac
    13501 cgtggcttcc tgacgcatca ccacttcatc tttcagcagg ttaagaatgt tgcgatccag
    13561 ttcttccggc acggcgtagc caccgtcttc atcggtaccc acctgcaatg ccttacgctc
    13621 cagatcgcgc agaccgtctt cacggccttt acgcaggaag cccacaaacg cctctttatg
    13681 ctcggtggcc agtttatttt gcgcaccacc tgccggacgt ttcagctcaa gcagctcttt
    13741 ttcaaggtcg cttttgagat tttccagctc gctgagtttc ccgttcaggg tttccacctg
    13801 cccggcaagc ttgccttttt cctgctcaat cgcatccacg cgcttgtcgt tctttgcttt
    13861 gaagtcgtca aacttctgct gcagctcctg cgcgacctgt tcgacatctt taatatcaac
    13921 cgccatcgta tttctcctga ttagaagttc agatttttca gtgcattcag tgcagagccc
    13981 acatcctcag cgtcgcgcag ggacagtgcg ccatagcccc cggccatgaa tgctttggcc
    14041 tgggtacggg agagtccgac atcacgcagg actctttcga tttttttctg ttcggggatt
    14101 tccccgcggg ccagtgcgtt cttgacgtcg ctgatccgcg cctcgtcgtt agacgggaac
    14161 gtcaccaggc tgacttccca gaggtcgatt tctttcagca gaaaggcttc tttgctccgg
    14221 tcgtattccc agtctttcag gacgtaccca atagaaaggc cggttaacga accggccttc
    14281 atgtgtgcat gtgcgcgttt tgcgagggga tcatcatcaa taagcaaccg tcccctgacg
    14341 taaagcccga catcgtcttc cttcatttcg gtgtaaacac cgatgggttc atccatgcgg
    14401 tgctgccaga gcagcgcagg taacgctttt ctgtcactcc acgcccgcag ggaagcagca
    14461 aatgccccgg acatcaccac atcatcgtgg ctgtccttta caccaaagac ggagccatac
    14521 ccttcaaact caccggagtc actgacagat ttcagactca gcggtacatc aagacgttgt
    14581 ttcgtctgca ttggcgttat ccttctgctt accggcttta ctgccatcgg agggtttcgt
    14641 ggtcatgttc atcggtgtga gatagacatc accaccggga cgcggattca tatcttccag
    14701 gtcgcggcag tcattgggag agtaaattcc ccagttgatc ccggtggcgt aggcttcaaa
    14761 acgggacttc atatccccgc gcagtaacgc cccggcgtta aatttggcgt aataaacgcc
    14821 ctgcttactt tttcgtacca gtccggtgtt gatccgctgt tcgatgcggg tcagatacgg
    14881 caccagtgaa tagttgataa atcccagccc cagctcttcg atattgttga aggtggcgcg
    14941 atcggtgttc tgcaccatgt gcaacggcac ccggaacaga cgacagattt cttcaagctg
    15001 aaacttgcgg gtttccagga actggctgtc ctcggcgttc agcgccatcg acttccagtc
    15061 cagccccatc tcaaggatca tcgggcggtg agcattgcca agcccggtgt gacgctcctc
    15121 aaaatctttc ttcaggcgct cataagcctg atctgacagc gtctgctctg tacgcaacac
    15181 acccgacgtc accgcgccat tgctgaacag tctggccccg tgctcttcgg tcgctgccgc
    15241 cagcgatatt gcctcgcggg cataggcgat gggattcagc cccaccagtc cgtccagcgt
    15301 cagcgtgcgc acatgccaga tatcctcctg gctcagtaca tccgtggagc catccgggaa
    15361 tgtgacctga tagatcggct cccagctact gttaagcttc ggttccacac agccgggatc
    15421 gacgggcagc agttcagcca cttcgccaaa tgctttcact ttgtaggcgt aaaagtttcc
    15481 ccgcaggcac agacaggtga ccaccagctc ccagaactcc tgcggcgtca tatagccatt
    15541 gggatgcgtg gagatcagtt tatgcagacg ttcgccggtg gctctctgct tcaggctgcc
    15601 gttcaggtga tacagattgc agggcaacat cccgaccgac tctgccagca ctctgacgca
    15661 ggaaaaaacc gccgtcagtc gcatggcccg ctgactgctg atctgctttc cggtataggt
    15721 gtcgtaggac aacccgatgg catccgccag ctctgctggc gtggtcaccg gtgcgtcact
    15781 ttttcgttga aataatcccg aaaagaacac tatttacctc caccaacaga cagctgtgta
    15841 cgatcgagat atcgcgctac cagccacgac cagaacaggc acaacgcccc ggcaacaaca
    15901 aaccccgccg ggggataaat cagccaggca ccatacgcca gcaaaagcgc ccccagcacg
    15961 cccaccagag gcgcgagaat cagcatgatc ataattacct cagttaaagc gagcggatcc
    16021 cataggactc aatgtggtca gacagcgtgt cttctttctc gtacagcatg gctctgccaa
    16081 ccgccataat cagcgcaact gcaccgtcaa ttttgttttc cgcctgctct ttgacgggtt
    16141 tcaccacatc atcgttaccc ggaatggttt tgccgaccac attgccgata caccaggtca
    16201 tgatgggatt gccatcatga tgaaagcgcc ccgattcaat tgccgcttcc agctctttca
    16261 tcgggtcgga catgttggtg tagttctgaa tgatagtgac gggattcagg tcttcatcag
    16321 caaggtcatg tgacaacccg gtcgccccga aggggtcgat gggtgactca ctgaccgggc
    16381 tgattttgtt cgccgctttg gcctcctcga ggatgtagcg ataatccacc tccgcaccat
    16441 cggtaacggt cagaacgccc atttccaccc atttctgaaa gcgttcggct gtccggcgat
    16501 cttcattttt ctcgacgctg tacaccgtgt catacggtac ccagaagcgc ggagccacac
    16561 tgtagtaatg cgttttaccg tcaatctcgc gggtataaag tcgcgccatg ctgttcatat
    16621 ccagcttacg cgccaggtca aaggccagaa tgcacggctg cccctcgaac tgctcaaggg
    16681 tcagtgattt atcctcgcag ctctgccagc tcaccaggtt gaaatacgcc gaacgcgccg
    16741 acacccagat attgaggtgt tttgttttaa agacgtttgc cagacgggcg ttatttttcg
    16801 cacgctgctg ctgacttaac aaaaattcgc gataaaccga cacgccaata ttcgggttag
    16861 ctttttccag cacctgcggg tcggtccagt catcgccttc gtcaacggta tagatgatcc
    16921 cgaacagttc atcgttgggt accgacccgt tgagcatctc gataacttcc cgtcgcttgt
    16981 cgtagcacgg cccctcaatg ttgtacccgg cagtagtaat ggcccacatc agtggctgac
    17041 gtcgcgcccc catcccggta agcatcgtgg tgtaaagcgc atcggtggcg tgctcgtgat
    17101 attcatccac caccgcacag tggggtgatg aaccatcacc ggggttaccg atcagcggtt
    17161 caaaccgcgc gccatcctcc ggacgattaa tgtttgaggc gttaacctca atcccgaacg
    17221 cttccgtcag catgggtgtg cgtttacaca tcagtcgcgc cgggcgaaag acttcccacg
    17281 cctgtttctc tgtcgtggca ccggaataca cttccgcgcc aaactcgtta tcacaggcaa
    17341 aacaatacag ggcaacaccg gcagagattg ccgatttgcc gttcttacgg gggatttcgg
    17401 tatacacctc ccggaagcgg cgcagccggg accctttatt gacccagcca aacgcacagc
    17461 agaccacaaa tagctgccac ggctccagcg tgatgggcat cctcttgaat gcccactcac
    17521 ccttggtgtg cggcaacagc tgaataaatt tggcggcccg ttcagccagg tccttgtcga
    17581 agcggtaacg aaacgactta cttttttccg ccatcaggtc atcaagatgg cgctggcagg
    17641 cctgaatcac aaactggcag gccacaatct ttccgcgcac aacatcacgg gcatactgat
    17701 tggcagcatt tacgttgggg taagatttcc ggctcatgac tcgatgattt tcagaaacgg
    17761 gttagtggct ttcttctgcc ccgccaggcc aatcagacgc tggcggctgc tggggtcgag
    17821 tccgagcatt gcccccgtgc tgctcatctc ggactcctgt tcttttttgg cggtcagctc
    17881 cggatttttg accctgccgc ccattgcacc ggtgatggtg ttgccctgta tggcaatatt
    17941 tttcacggca cgtcgccaga actcataggc cacgcaccac cgctcaagca ccgcgaggtc
    18001 agtcacgcac aacaggccct gaccgcagag ttctttggtt gtcagttgcc acatgatcgt
    18061 ggcgagaggg agattttctt ctgcgaacca ctccggtggc tcaacacctt tgatgggcgt
    18121 aaaaacaggt tcatctttat tcagggctcg cttgccgggg tttccggcca gcgccttgcg
    18181 cgccgttggc ttggggcgac gcccggaacg ccccgccgtt ccagccatat gcggcactcc
    18241 tggttaaatt tcatttttcg cgggtataaa aaaacgatgg ggcgggcagt ccggaagacg
    18301 tcaggtcaca gggatttgac ccgcccctcc cctcagacag ttgagaatta ttatcacttt
    18361 aaccgttcac gggccgtctt cgccttatga cacggccagc acagactctg cagattactg
    18421 tcagcatcag tgccgccatg cgctttaggg atgatgtggt caacagtttt cgcctcacgc
    18481 accacaccag aacgcagaca taactgacac aggcctttgt cacgcttcag gacacgcgcg
    18541 cggatactgt cccacttcga accgtagccg cgctgatgac gggattgtcc aggtttgtat
    18601 tgcttccagc cttcgctttt gtggctttcg caatagcctg acgggtcagt ggtggtatta
    18661 cggcaacctc gagcacggca ggctttcggg attcgtggcg gcatatgtac taatctccga
    18721 tttatccaaa tttaactgcc ataatgccga cattctctgc cattgttggc tccgtttatc
    18781 cgttaaaagg gatatcagtt aagttatccc gtgtagggta taaaccatta tcaaagccac
    18841 tctgtaggga gtggcttttg taatgacaat aaaaagcccc gcgaatacga ggcttttagc
    18901 atgtggaaaa ggaagtttat tgtaactttt caagataagg agctatgttg ctaacttttt
    18961 tgtagttcag atcatccggt agttgaacag caggattata tacaacccat atagattcag
    19021 acttgccatc tgaaccatct gtgtttttac atgagcgtaa cttgtaatga atgattctat
    19081 ctacgtcagc gtactcggag gttgcataaa cttcatattt attatctcca tggaaaagga
    19141 tagttttaac taattttgta gatgacatgt ctgctccttt gtaattgatg ggtatgacat
    19201 atgaccacca attacaatgc catatttctg gtgattattg cagcagcgaa attacaaacc
    19261 aaacccaaag atgggctttg taatgactac agtaacgaac tgcacaatgc gcctgtattt
    19321 cgaggatgac gtccaaatac gttaatcttc tcgcgaacgc tctcactaca cattcgctct
    19381 acaattcgcc aaacaacctt ttcaggtaaa aatttcggcg ctagtgctga aatagcacgc
    19441 cacagacccc gactaagcga gcatgctgtg ctaccgaaac taaagatgac gaacgaaata
    19501 gacgtgataa acgcccagca cccagagaga aaagctgaga tgcggtgata aagcttagtc
    19561 atgtattgct cctgtttttt tggttttcat cgcccgatca tttcaggcat tgcgtcctga
    19621 tgtattcctg caggtagtta acctgcgcgg ttatcctgtt gattccactt ctgagacggt
    19681 aataattgag ttcagcatct gctgtaagtc ttgggctttc tccatcgccc atgctgctgg
    19741 ctccggtcgt tgactttgca caggtggcgg cgacttgcag gcgcttacga ccagcagaaa
    19801 catcagcacg gagactttcg atagtcgcgt tagcatcagc aagctccttt gtgtatctgg
    19861 cgtcgagttc tgctacatca cgttgacgct tctgcatatc agcgatgatg gatgcggctt
    19921 tatcgcgctg ctctttgtag gtcatggcgt tatcacggta atgattaaca gcccatgaca
    19981 ggcagacgat gatgcagata accagagcgg agataatcgc ggtgactctg ctcatacctc
    20041 aatctctctg accgttccgc ccgcttcttt gaattttgca atcaggctgt cagccttatg
    20101 ctcgaactga ccataaccag cgcccggcag tgaagcccag atattgctgc aacggtcgat
    20161 tgcctgacga atatcgccgc ggtcaatcat cggtaaagcg ccacgctctt taatctgctg
    20221 taatgccact gagtcctggc ttctgggaga gaagtctttc agcccaagct gcttgcggta
    20281 agcatcccac caacgtgaaa gaagttgata acggcctgca gctgttgatt tgagtttcgg
    20341 gtttagcgtg acaagtttgc gagggtgatc ggagtaatca gtgaagagtt cgccaccgac
    20401 aataacgtca taaccgtggt tacgtgtcgg ttgtcgcccg ttatccgttc cttctgacca
    20461 tgccaccata tccaggaaag ctttacgctg ggaatttagt acctgcataa attactcctt
    20521 agagccacca aacttgttac cgattactct cattgcagcc ccacgaatag catcgacacc
    20581 gatcaaccca acgccaccac caatggcaac agaaagcgat ttaggccatc cgacatactc
    20641 aagcgcggat gcaaaggtca gcgtcagagc gccacagagc aaaatctcga gcgtttttct
    20701 cttccagcca ccaccaccgc caaaataggc aatgcgcaag ccagccataa cgatcgacat
    20761 aatcactgcg cccagcggtg tgtctccacg ccaccagctc tggaccaact ccagccaagt
    20821 atttgggtta tgaggcattt gtagttatct ctcacctcgc tgatacagca ggtgcaaatt
    20881 gaggaaacat catgtaccgc aaatcagaag cggaaacgtc aaagaagccg agccaatgga
    20941 taactgcggg atagactagg cccaacgaat ccccaggccc agaaacgaca aaacccgctc
    21001 gacggcgggt ttaagctgtg tggcgaagta accactctta acacaataca atactttttg
    21061 cgtacgcgtt agtgttttga tagaattttc agccacataa aaattcattc ttataattcg
    21121 ggatatataa tggatataac ttgtttagaa tgtggcaatg ttcttgacga cccaactgta
    21181 gcttgcgata aatgcggtgc cacgcctcat gttgtagtgc tgggcaaaca atcgtacttt
    21241 cctattggtg ctgtaacagc aaatcttgaa aaaaatgatt caagagcatt tgattatcga
    21301 ttaggtgaag tttgggatct aaaaaatgaa gtcacatctg aattcataac cagaattgag
    21361 aaaaaattta gccgaaaaaa caaatttcat aacttcctag actcagatca caacccttca
    21421 tccattccta cgatcctaaa aaaatacatt aataaaaata atgaattcat tgatttatct
    21481 agagctataa tagagaagct taaacataat gctaataacg aatcgagagt tgcccaactt
    21541 caggggggga gcgttgtttt catccactat aagtctaccg aaccagagga tttggggaaa
    21601 cttctaatcg taatggttga taaacaaagc gcctatgact ttgattcgga taagttgacc
    21661 ccaacaagat taaatccaat taataccgat gccttacggc aggctgcgat gttcgattta
    21721 actttattcg aagccagtta tccagaaaac aagggtgact catatgtaca tttcttgcaa
    21781 ggtaaatcta aaagcgattt tttcaaagac tcattaggtt gccgacatga ttcggacaat
    21841 aaaagaagca ttcagcaatt attcagtgct atagatattt ttgctagtaa aaactcactc
    21901 ggtcgtgtac tgcgtgatac tattgacaat gaagttaaat ccttactgga aaaaaaatca
    21961 aaagataaac acggaaataa gtccgttaag atagaggata tttcaaaaat aattgactca
    22021 tgcctgactg attcacacaa atgtaaggga acgtttgtcg attttgttaa tcttaatggt
    22081 ttccagattg accctcaatt tgaaccaact cctaaagcag ctgaaagcgc gcttacaatt
    22141 gaagtggcag ataacgacaa taattttaag ttgaaaataa tgcgtggagc tattggagac
    22201 gaaaagtcaa ataagcctgt aattctcact gacaacaaat gcgaaattgt gataaaattg
    22261 agtcaggcaa attatgatga actcaaaaga tatagagaca gctaataatg acaattgctg
    22321 atgacttatc aagattagcg cagattatta acggagcctc aagcagagtt gagggctact
    22381 acactgtcat aagtcttgaa gaaagcattg ttattgtaaa tagttctgaa ataattagac
    22441 tgttacaatc tataggttat aaa
//
LOCUS       DAZUDJ010000074        22062 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.074, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000074 DAZUDJ010000000
VERSION     DAZUDJ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22062
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.074"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..2694
                     /gene="cas3"
                     /locus_tag="ACHY1N_003922"
     CDS             <1..2694
                     /gene="cas3"
                     /locus_tag="ACHY1N_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
                     /protein_id="HFS4046134.1"
                     /translation="KYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVA
                     AMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPEL
                     KIQESARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGH
                     HGRPPDRMDELDNFLPEDKAAARDFLLAIKALFPRIEIPAFWDDDEGIELIKHLSWYI
                     SATVVLADWTGSSTRFFPRVAQAMDIKHYWQKALVQAQNALTVFPPKAETAPFTGINT
                     LFPFIENPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGL
                     FFGLPTMATANAMYDRLVKTWLSFYSPESRPSLVLAHSARTLMDRFNESLWSGDLIGS
                     EEPDEQAFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKIL
                     LADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGAEGQQE
                     APLLGKDDYPWLTHVTKTDVHSHRVATRKEVERSVSVGWLHSEQECIARIESAVSQGK
                     CIAWIRNSVDDAIQVYRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCS
                     LQRASQVIVCTQVIEQSVDIDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGK
                     DERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGAIQMPH
                     AARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRARAKKYVLNFRPGYAANINDYLP
                     EKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEG
                     DAFRQWCVEQRQDPEMANVILVTDDESCGYSAREGLIGKVG"
     gene            2792..4354
                     /gene="casA"
                     /locus_tag="ACHY1N_003923"
                     /gene_synonym="cse1"
     CDS             2792..4354
                     /gene="casA"
                     /locus_tag="ACHY1N_003923"
                     /gene_synonym="cse1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse1/CasA"
                     /protein_id="HFS4046135.1"
                     /translation="MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADL
                     QGAAWQFLLGLLQTSFAPKDQRRWDDIWEDGLEAEKLREALLSLEHAFQFGPDSPSFM
                     QDFDELKVKATSIASLLPDAPGKQTKERNTDHFIKRDTTQHLCLHCVPLALFSIQLNA
                     PIGGRGYYPGLRGGGPLTTLIELLEYQGNQQTPLWRKLWLNVMPQDEADLPLPKTFDD
                     LVFPWLAPTRTSELDGAVVTDEQVNKLQAYWGMPRRIRIDFKTTSIGNCDICGRQSDA
                     LLGLMSLKNYGVQYVMWRHPLTPYRLPLKEGGDFYSVKPQPGGLIWRDWLGLIEVGNS
                     KNNTELPAQVVKLLNASNLKQTRVGLWGFGFDFEDMKVRCWYEHHFPLLLNKKEDLIP
                     KLRLAAQAASHILSLLHRALKEAWFSEKKTTKLDFGFVDIDFWNKTQHRFLRLVRKIE
                     EGQDPYELLSKWQKEMWLFARQDFDDRVFTNPYEPVDLERVMTARKKYFTTSAEKQNA
                     NAAREKKQEAAE"
     gene            4351..4884
                     /gene="casB"
                     /locus_tag="ACHY1N_003924"
                     /gene_synonym="cse2"
     CDS             4351..4884
                     /gene="casB"
                     /locus_tag="ACHY1N_003924"
                     /gene_synonym="cse2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse2/CasB"
                     /protein_id="HFS4046136.1"
                     /translation="MSIVKDEHKVALRKWHEELQDKRGERASLRRSTTVNDVCLTDGF
                     RLFLKNRQIKWQDEPEWRITALALIAAVSANVKAIDERQPFAAQLAAVMKKGRFTRLL
                     AVKTPDDLLRQLRRAVKLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRI
                     RWALEYYQAGDADNEQN"
     gene            4899..5972
                     /gene="cas7e"
                     /locus_tag="ACHY1N_003925"
     CDS             4899..5972
                     /gene="cas7e"
                     /locus_tag="ACHY1N_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas7/Cse4/CasC"
                     /protein_id="HFS4046137.1"
                     /translation="MTTFIQLHLLTAYPAANLNRDDSGSPKTVILGGATRLRVSSQSL
                     KRAWRTSELFEQALAGHIGVRSGRIAREAATILIEKGIEDKKAIEWAVEIADYLGKAK
                     KDKKQKNDKKPKDPLTSAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEKDLALLRK
                     DRMAVDIAMFGRMLAKKPGFNVEAACQVAHAFGVSETIVENDFFTAVDDLRQASEDAG
                     AGHVDETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNS
                     FASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKT
                     ECASFDVMNKQGSMKDVLDFICA"
     gene            5983..6729
                     /gene="cas5e"
                     /locus_tag="ACHY1N_003926"
     CDS             5983..6729
                     /gene="cas5e"
                     /locus_tag="ACHY1N_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA];
                     GO_process: GO:0051607 - defense response to virus
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cas5/CasD"
                     /protein_id="HFS4046138.1"
                     /translation="MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGV
                     GIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPE
                     LLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPL
                     APLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDV
                     PLNRQQWLFGERTVNQGPWLSKEEPCTSQE"
     gene            6711..7361
                     /gene="cas6e"
                     /locus_tag="ACHY1N_003927"
     CDS             6711..7361
                     /gene="cas6e"
                     /locus_tag="ACHY1N_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas6/Cse3/CasE"
                     /protein_id="HFS4046139.1"
                     /translation="MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQ
                     FLYRREELQGAFRFFVLSQERPAESDTFTIECRSFAPELCTGQQLCFNLRANPTICKA
                     GKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQ
                     LRRENSRQLIQFSSVDYTGMLTVTDPGLFVQRLSQGYGKSRAFGCGLMLIKPGAEA"
     gene            7358..8278
                     /gene="cas1e"
                     /locus_tag="ACHY1N_003928"
     CDS             7358..8278
                     /gene="cas1e"
                     /locus_tag="ACHY1N_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004520 - DNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA];
                     GO_process: GO:0051607 - defense response to virus
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endonuclease Cas1e"
                     /protein_id="HFS4046140.1"
                     /translation="MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHI
                     PVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQ
                     AKLALTEDLRLKVVRKMYELRFREPQPARRSVEQLRGIEGSRVRQTYALLAKQYGVKW
                     NGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYD
                     IADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGE
                     IEPPQPAPDMLPPAIPEPETLGDSGHRGRG"
     gene            8278..8571
                     /gene="cas2e"
                     /locus_tag="ACHY1N_003929"
     CDS             8278..8571
                     /gene="cas2e"
                     /locus_tag="ACHY1N_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endoribonuclease
                     Cas2e"
                     /protein_id="HFS4046141.1"
                     /translation="MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIW
                     QQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ"
     repeat_region   8668..9307
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=8668..8696
                     /rpt_unit_seq="gtgttccccgcgccagcggggataaaccg"
     gene            complement(9389..10426)
                     /gene="iap"
                     /locus_tag="ACHY1N_003930"
     CDS             complement(9389..10426)
                     /gene="iap"
                     /locus_tag="ACHY1N_003930"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase isozyme conversion
                     aminopeptidase"
                     /protein_id="HFS4046142.1"
                     /translation="MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFF
                     PGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIA
                     AHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKN
                     TPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGV
                     KTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSV
                     EATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIM
                     LPLVKELAKAS"
     gene            10678..11586
                     /gene="cysD"
                     /locus_tag="ACHY1N_003931"
     CDS             10678..11586
                     /gene="cysD"
                     /locus_tag="ACHY1N_003931"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HFS4046143.1"
                     /translation="MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
                     KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST
                     TSERQGRVIDRDQAGSMELKKRQGYF"
     gene            11588..13015
                     /gene="cysN"
                     /locus_tag="ACHY1N_003932"
     CDS             11588..13015
                     /gene="cysN"
                     /locus_tag="ACHY1N_003932"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HFS4046144.1"
                     /translation="MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYSEETFTRIRKDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSE
                     SMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQ
                     RVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAV
                     QSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNG
                     IGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSA
                     FELELNALVRRHFPHWGARDLLGDK"
     gene            13015..13620
                     /gene="cysC"
                     /locus_tag="ACHY1N_003933"
     CDS             13015..13620
                     /gene="cysC"
                     /locus_tag="ACHY1N_003933"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HFS4046145.1"
                     /translation="MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTV
                     AGVLEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLV
                     VLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
                     GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS"
     gene            13670..13993
                     /locus_tag="ACHY1N_003934"
     CDS             13670..13993
                     /locus_tag="ACHY1N_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HFS4046146.1"
                     /translation="MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPML
                     IYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALF
                     MWLLG"
     gene            14187..14498
                     /gene="ftsB"
                     /locus_tag="ACHY1N_003935"
     CDS             14187..14498
                     /gene="ftsB"
                     /locus_tag="ACHY1N_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HFS4046147.1"
                     /translation="MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNA
                     KLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNN
                     R"
     gene            14517..15227
                     /gene="ispD"
                     /locus_tag="ACHY1N_003936"
     CDS             14517..15227
                     /gene="ispD"
                     /locus_tag="ACHY1N_003936"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HFS4046148.1"
                     /translation="MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHA
                     LLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWV
                     LVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQENT"
     gene            15227..15706
                     /gene="ispF"
                     /locus_tag="ACHY1N_003937"
     CDS             15227..15706
                     /gene="ispF"
                     /locus_tag="ACHY1N_003937"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HFS4046149.1"
                     /translation="MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK"
     gene            15703..16752
                     /gene="truD"
                     /locus_tag="ACHY1N_003938"
     CDS             15703..16752
                     /gene="truD"
                     /locus_tag="ACHY1N_003938"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HFS4046150.1"
                     /translation="MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHI
                     LVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLS
                     AFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYF
                     GAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQ
                     VVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEK
                     AAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVV
                     RELINTTGDYAHIAE"
     gene            16733..17494
                     /gene="surE"
                     /locus_tag="ACHY1N_003939"
     CDS             16733..17494
                     /gene="surE"
                     /locus_tag="ACHY1N_003939"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008252 - nucleotidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HFS4046151.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
                     PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVD
                     EGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW"
     gene            17488..18114
                     /gene="pcm"
                     /locus_tag="ACHY1N_003940"
     CDS             17488..18114
                     /gene="pcm"
                     /locus_tag="ACHY1N_003940"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004719 - protein-L-isoaspartate
                     (D-aspartate) O-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HFS4046152.1"
                     /translation="MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKA
                     WDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCS
                     VERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMT
                     QLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            18299..19393
                     /gene="nlpD"
                     /locus_tag="ACHY1N_003941"
     CDS             18299..19393
                     /gene="nlpD"
                     /locus_tag="ACHY1N_003941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HFS4046153.1"
                     /translation="MSLVSLWLAGCSDTSNPPAPVSSVNGNAPANTNSGMLITPPPKM
                     GTTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENGRIVYNRQYGNIPKGS
                     YSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVGQTLQVGNASGTPITG
                     GNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSANKMLPNNKPAATTVT
                     APVTVPTASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASEGGNKGIDIAGSKGQA
                     IIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEVKAGQKIATM
                     GSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            19456..20448
                     /gene="rpoS"
                     /locus_tag="ACHY1N_003942"
     CDS             19456..20448
                     /gene="rpoS"
                     /locus_tag="ACHY1N_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HFS4046154.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(20569..20976)
                     /locus_tag="ACHY1N_003943"
     CDS             complement(20569..20976)
                     /locus_tag="ACHY1N_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4046155.1"
                     /translation="MALRNKAFHQLRQLFQQHTARWQHELPDLTKPQYAVMRAIADKP
                     GIEQVALIEAAVSTKATLAEMLARMENRGLVRREHDPADKRRRFVWLTAEGEKILAAA
                     IPIGDSVDEEFLGRLSGEEQELFMQLVRKMMNA"
     gene            21123..21716
                     /locus_tag="ACHY1N_003944"
     CDS             21123..21716
                     /locus_tag="ACHY1N_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-oxidative hydroxyarylic acid decarboxylases
                     subunit B"
                     /protein_id="HFS4046156.1"
                     /translation="MKLIVGMTGATGAPLGVALLQALREMPNVETHLVMSKWAKTTIE
                     LETPYSARDVAALADFSHNPADQAAIISSGSFRTDGMIVIPCSMKTLAGIRAGYADGL
                     VGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAMVPPMPAFYNHPETVDD
                     IVHHVVARVLDQFGLEHPHARRWQGLPQARNFSQENE"
     gene            21716..>22062
                     /locus_tag="ACHY1N_003945"
     CDS             21716..>22062
                     /locus_tag="ACHY1N_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase domain-containing
                     protein"
                     /protein_id="HFS4046157.1"
                     /translation="MAFDDLRSFLQALDDHGQLLKISEEVNAEPDLAAAANATGRIGD
                     GAPALWFDNIRGFTDARVTMNTIGSWQNHAISLGLPPNTPVKKQIDEFIRRWDNFPIA
                     PERRANPAWAQNTV"
BASE COUNT         5377 a         5385 c         6032 g         5268 t
ORIGIN      
        1 aaatatcctt taagtttact gaaggataaa aatattgtga ctttttttga tttctgggga
       61 aaaacccgac gcggcgagaa agacgggggc gacgactatc accttctttg ctggcattcg
      121 ctggatgtag ccgcgatggg ctatttaatg gttaaaagaa attgcttcgg gctggctgat
      181 tattttcgtc aattagggat ttctgacaag gaacaggcgg ctcaattttt cgcctggttg
      241 ctgtgctggc acgatattgg aaaatttgcc cgctcttttc aacaacttta cctgccccct
      301 gaactcaaga ttcaggaaag tgccagaaaa aattacgaaa aaatctctca ttcaacgctg
      361 ggctactggt tgtggaatca ttatttaagt gaatgtcagg agttacttcc ttcatcttcg
      421 ctctctccgc gcaaacttag gcgagtgata gaaatgtgga tgcccgtgac gacagggcat
      481 catggtcggc cccctgatcg tatggatgaa ttggataatt ttctgcctga agacaaagct
      541 gcagcacgag attttctcct tgcaatcaag gcactgtttc cgcgaataga gatccccgca
      601 ttctgggatg atgacgaggg cattgaactt ataaaacacc tttcctggta tatctctgca
      661 accgtcgtac tcgcagactg gacaggttcg tcaacgcgat tttttccacg cgtcgcacag
      721 gcaatggata ttaaacatta ctggcagaag gctttagtgc aggctcaaaa cgcattaacc
      781 gtctttcctc caaaagcaga aaccgcacct ttcaccggaa ttaatacact gtttcctttt
      841 attgagaatc cgacaccgtt acagcaaaag gtgctggatc tggatatcag ccagccagga
      901 ccgcagttat ttattctgga agatgtgact ggcgcaggta aaacagaagc ggcgcttatc
      961 ctggcgcaca ggttgatagc tgcggggaaa gctcaggggc tgttttttgg tctgccaaca
     1021 atggcaacgg ccaatgccat gtacgatcgg ctggtcaaaa cctggctttc tttctattcg
     1081 ccagaatctc gccccagcct ggtgctggca cacagtgccc gcacattaat ggaccgcttt
     1141 aatgaatcac tctggtccgg tgatttaatc gggtcagaag aaccggatga acaagctttc
     1201 agccagggtt gtgcggcctg gtttgccgac agtaacaaga aggcgttgct ggctgaaatt
     1261 ggcgtcggca ccctggatca ggcgatgatg gcagtgatgc cgtttaaaca taataatctg
     1321 cggcttctgg ggctgagtaa caaaatcctg ctggctgatg agatccacgc ctgtgacgct
     1381 tacatgtcgt gcattcttga agggctgatc gagcggcagg cgcgtggcgg aaacagcgtt
     1441 attttgcttt ctgctacgtt atctcaacag cagcgcgaca aactcgtcgc cgcctttgcg
     1501 cgtggtgcag agggccagca agaagcccca ctcctgggaa aagatgatta cccctggctg
     1561 acgcatgtca cgaaaaccga tgtacattcg caccgggtag cgacgcgcaa agaagttgaa
     1621 cgtagcgtga gcgtgggttg gctccatagt gaacaagagt gtattgcgcg tatcgaatcg
     1681 gcggtaagtc aggggaaatg catcgcctgg attcggaatt ctgttgatga cgctattcag
     1741 gtgtatcgtc agctgcttgc ccgcggcgtc attcctgctt ccagcctttc actttttcat
     1801 agccgctttg cttttagcga tcgccagcga attgaaacgg aaacgctggc acgctttggt
     1861 aaatattgta gtttacagag agcgtcacaa gtcattgttt gtacacaagt aattgaacaa
     1921 agcgtggata ttgacctgga cgaaatgatc tccgacttgg cccccattga tttgctaatc
     1981 cagcgagcgg ggcgattaca gcggcatatc cgcgatatta atggtcagtt aaagcgtgac
     2041 ggaaaagacg agcgttcccc ccctgaattg ctgattctgg cccccgtctg ggatgacgct
     2101 cctggtgacg aatggttcgg cagtgccatg cgtaacagtg catatgtcta tcccgatcat
     2161 gggcgaatct ggctgacgca gcgtgtgctg cgtgagcaag gcgctattca gatgccacac
     2221 gcagcccggc ttcttattga atcagtttac ggtgaggacg tggtaatgcc ggaaggattt
     2281 gcccgcagcg agcaggagca agtgggcaaa tattactgtg atcgcgcaag ggctaaaaag
     2341 tatgtgctga acttcaggcc cggctatgcc gccaatatca acgattacct tccggaaaaa
     2401 ctgtcgacac gtctggctga agagtctgtt tccctgtggc tggctacctg tattgacggt
     2461 gtggtgaagc cttatgccac cggtgctcac gcatgggaaa tgagcgttgt cagagtgcgc
     2521 cgaagctggt ggaaaaaaca tcgggatgag ttttctttac tggaagggga tgcgttcagg
     2581 cagtggtgcg ttgaacagcg gcaagatccg gaaatggcaa acgtgatttt agtcaccgat
     2641 gacgaaagtt gcgggtattc ggccagggag ggattgattg gcaaggttgg ttgagatgtc
     2701 tgcgacagga ctctctgaat agttgatata cagaaaagga tggaaggatg gacaaccgac
     2761 ctgggatggt cttttttacg agaggatgcg tatgaactcg ttttcacttc tgacaacccc
     2821 gtggttgccc gttcgtttta aagacggaac gacaggcaaa ctggcaccag tcgatctggc
     2881 tgatgaaaat gttgtcgata tcgctgcgcc gcgggcagat ctccaggggg cggcctggca
     2941 gtttttgttg gggctactac aaaccagctt cgcgccaaaa gatcaacgtc gttgggatga
     3001 tatctgggaa gacggactgg aagctgaaaa gctaagggaa gcattgctgt ctttagaaca
     3061 tgcttttcag tttgggccag attccccttc atttatgcag gattttgatg aattaaaagt
     3121 taaggcaact tctattgctt cgcttcttcc tgacgcacca ggaaaacaaa caaaagaacg
     3181 aaatacagac cattttatta agcgagacac aactcagcat ctgtgcctgc attgtgtgcc
     3241 tttagcgctt ttttcaatcc agttgaatgc acctataggt ggacgcggtt actatcctgg
     3301 gctacgtggc ggagggcctc tgacgacact tatagaattg ctggagtatc agggcaatca
     3361 acaaacccct ttgtggcgaa agctgtggct aaacgtaatg ccgcaagatg aagccgattt
     3421 acctttacca aaaacctttg atgacctggt ctttccatgg cttgcaccga cgcgtaccag
     3481 cgaactggac ggtgctgtgg taacggatga acaagtcaat aaacttcagg cctactgggg
     3541 aatgccacga cgtatacgta ttgattttaa gacaacctca ataggtaact gcgacatttg
     3601 cggtaggcag agcgatgctc ttttgggctt gatgtcactc aaaaactatg gtgttcaata
     3661 cgtcatgtgg cgccatcctc taacacctta ccgtctgccg cttaaagagg gtggagattt
     3721 ttactcagtt aaaccacaac ctggtggttt aatctggcgc gactggttag gcctcataga
     3781 ggtaggtaac tcaaaaaaca atactgaact ccccgcacag gtcgtgaaac ttttgaatgc
     3841 cagcaatcta aagcagacaa gggtgggctt atggggattt ggttttgatt ttgaagatat
     3901 gaaggttcgt tgttggtatg aacaccattt cccgctgttg ttaaacaaaa aagaagacct
     3961 aatacctaag ttgcgtctgg cagcgcaagc ggcatcacac attctaagct tgttacaccg
     4021 agcgttgaaa gaagcatggt tctctgagaa gaaaaccaca aagcttgatt tcggttttgt
     4081 ggatattgac ttctggaaca aaactcagca tcgattcctg agattagtgc gcaaaattga
     4141 agaaggtcag gatccgtacg aattactcag taaatggcaa aaggaaatgt ggttattcgc
     4201 gcgtcaggat tttgacgatc gtgtctttac caatccatat gagcccgttg atttggaacg
     4261 cgtcatgacc gcacgcaaga aatattttac aacatcagcg gagaagcaaa atgctaacgc
     4321 cgccagggag aaaaagcagg aggctgctga atgagtattg taaaagatga gcataaagtt
     4381 gcgctgcgta aatggcatga agagttgcag gataaacgcg gcgagcgtgc cagtctgcgg
     4441 cgtagtacga cggttaatga tgtttgtctg acggatggat ttcgcctgtt tcttaagaac
     4501 agacaaataa agtggcagga tgaacccgag tggcgtatca ccgcactagc gctgatagca
     4561 gcagttagcg ccaatgttaa agctattgac gaacggcagc cttttgccgc gcaactggcg
     4621 gcggtaatga aaaaggggcg gtttactcgt ttgttggcag taaaaacgcc ggatgattta
     4681 ttgcggcagt tacgccgtgc ggtcaaatta ttaaacggtt ccgtcaatct tgactctctg
     4741 gcagaggggg tcttccgctg gtgccaggag agcgatgacc tgctcaatca tcaccgccgc
     4801 cagcagcgac caacagaatt tatccgtatc cgctgggcgc tggaatatta ccaggctggc
     4861 gacgccgata acgaacaaaa ttaataaagg actatctcat gacaacattt attcagcttc
     4921 atttgttaac cgcttaccct gctgccaatc ttaaccgtga tgattccggc tctccgaaaa
     4981 ctgtgattct gggtggagca acgcgtctgc gcgtttcctc gcaaagtctg aagcgtgctt
     5041 ggcgcacttc tgaacttttt gaacaggcgc tggcgggcca tattggtgtt cgtagcgggc
     5101 gtattgcgcg tgaggcggca actatcctga ttgagaaagg aatcgaagat aaaaaagcca
     5161 tcgaatgggc agtagagata gccgattatc ttgggaaagc caaaaaagac aaaaaacaaa
     5221 aaaacgacaa aaaaccaaaa gatccgctca ctagcgccga aactgaacag ctcgtccata
     5281 tcagcccggc agaatttgac gccgtaaaag cgctggccca tcaactggca gaagaaaagc
     5341 gcgcgccaaa agagaaagat ctcgctttgt tacgtaaaga ccgtatggcg gtagatatcg
     5401 ctatgtttgg tcgtatgctg gcgaaaaaac ccgggtttaa tgtagaagcc gcctgccagg
     5461 tcgcgcatgc gtttggtgtc agtgaaacga ttgtcgaaaa tgattttttc accgccgtag
     5521 atgatttacg ccaggcttct gaagatgccg gtgccggtca tgtagatgaa accggattcg
     5581 gttctgcgct gttctacacc tatatctgca ttgataaaga tctgctggta gaaaacctcg
     5641 gcggtgacga agcgttagct aatcagacca tacgtgcctt tacggaagcc gcacttaaag
     5701 tctccccaac cggcaaacag aacagctttg ccagccgtgc ctacgcctcc tgggcgctgg
     5761 cagaaaaagg caccgatcaa ccacgctctc tggcggcggc tttctatgaa cccattaatg
     5821 gcacacgtca gttagatgtg gcggtgcagc gtattacaac gcttcgcgaa aacatgaata
     5881 cggtctacga acagaagacc gaatgcgcaa gttttgacgt gatgaacaaa cagggaagca
     5941 tgaaggacgt gctggacttt atctgcgcgt aaggggcggc ttatgagcca atatctgatt
     6001 tttcagcttc atgggccgat ggcgtcctgg ggggtcgatg ctccaggtga agttcgtcat
     6061 acccatgaac ttccttcgcg ctcagcattg ctggggctac tggctgccgg ggtagggatt
     6121 cggcgtgatg ataccgaacg cttaaacgcg tttaatcgcc actattcact ggtggtttgc
     6181 gccagccgta acccgcgctg ggcacgggat tatcacacgg tccagatgcc aaaagaggtg
     6241 cgtaaagcac gttatttcag ccgtcgcgaa gagttgagcg accctgagct tttgagcgcg
     6301 attatctccc ggcgcgacta ctacaccgat gcctggtgga tggtggcggt ggcaacaaca
     6361 gccgatgcgc cttacagcct cgaacagttg caggacggtt tacgccatcc agtttttccg
     6421 ctttatctgg ggcgaaaaag tcatccgctg gcattacctc ttgcgccgtt actgctcgaa
     6481 ggcaacgcgt gtgatgcctt atgtaatgca taccaacagt atcaggatca tttccataaa
     6541 ctgaaagtct cactcccgaa acttcaggat gaatgctggt gggaagggaa acacgacggc
     6601 ctggtcgcga gcaaaatatt acgccgccgg gatgttcctt taaatcgtca gcagtggctg
     6661 tttggggaac gcaccgtcaa tcaggggccg tggctcagca aggaggaacc atgtacctct
     6721 caagaataac cttacatacc ggccagcttt cgcctgcgca gttgctgcat ctggtggatc
     6781 gcggtgaata tgtgatgcat cagtggctgt gggatctctt ccctggcggc aaagaaaggc
     6841 aatttcttta tcgtcgggaa gaactccagg gcgcgtttcg cttttttgta ctgtcgcagg
     6901 aacgcccggc ggaaagtgat acgttcacca tagaatgccg gtcatttgcg cccgagctgt
     6961 gtaccggaca acaactttgt ttcaacctgc gggcgaatcc aacaatctgt aaagcgggca
     7021 agcgccacga tctgctgatg gaggcgaaac ggcaggtgag ggggcaggcg gaaggaagtg
     7081 atgtctggtt gcatcaacaa caggcggcgc tggactggct ggcagcgcag ggggagagaa
     7141 gcggttttac actgctggat acctcggttg atgcctaccg acaacagcaa ctgcggcggg
     7201 aaaactcccg gcaactgatc cagttcagta gcgtggatta tacggggatg cttacggtca
     7261 ccgatcctgg gttatttgtg caacgcctga gccaggggta tggtaaaagc cgggcgttcg
     7321 gctgtggtct gatgctgatc aaacccggag cagaggcgtg acgtttgtac cactgagccc
     7381 gatcccatta aaagatcgca cctccatgat cttcctccag tacggtcaga tcgacgtact
     7441 ggacggcgct ttcgtgctga tcgacaaaac agggatccga acgcatattc cggtgggatc
     7501 ggtcgcctgc attatgctcg aaccaggaac gagagtttcc cacgcggcgg tgcatctggc
     7561 cgccacggtg ggaacactgc tggtctgggt cggtgaagcg ggcgttcgcg tttactcctc
     7621 cggacaaccc ggtggggcgc gggcagataa attactctac caggcaaagc tggctttaac
     7681 ggaagatcta cggttgaagg tggtgcgcaa aatgtatgaa ttacgttttc gtgaaccaca
     7741 gccagctcgc cgttcagtgg agcagttacg tggaattgag ggatctcgcg ttcgccagac
     7801 gtatgcatta ctggcgaaac aatatggtgt gaaatggaat ggtcgcaaat acgatcctaa
     7861 agactgggaa aaaggcgatg ttgtgaatcg ctgcatcagt gctgctacat catgtctgta
     7921 cggtatatct gaagcggcag tattagccgc gggatatgcg cccgctattg ggtttatcca
     7981 tagtggcaaa ccgctttcat ttgtttatga catagccgat atcattaaat ttgattcggt
     8041 tgtgccaaag gcatttgaaa tagcagcgag gcaacccgca gaacctgata aagaagtcag
     8101 attagcctgt cgcgatattt tccgtagcac taagttaacg ggcaaattaa taccgttaat
     8161 tgaggaagtc cttgccgcag gtgaaattga accgccacaa cctgcgccgg atatgttacc
     8221 gccagccatc cccgaacctg aaacgttggg cgatagcggt catcgaggac gcggctgatg
     8281 agcatggtcg tggttgttac agaaaatgtc ccgccgcgct tacgtggacg gctcgcaatc
     8341 tggctactgg aagtgcgtgc cggtgtgtat gttggtgata catcaaaacg tattcgggag
     8401 atgatctggc agcaaattac ccaactggct ggttgcggaa atgtggtgat ggcctgggcg
     8461 accaataccg agtcgggttt tgaatttcag acctggggag aaaacagacg tattccggtg
     8521 gatttggatg ggttacgttt ggtttctttt cttcctgttg ataatcaata agttatccgt
     8581 tctttaaaaa taaggaaatg ttttaattta gttggtagat tgttgatgcg gaataaattt
     8641 gtttaaaaac agttatgtat gcttagtgtg ttccccgcgc cagcggggat aaaccgacga
     8701 ccaaatgatc tacgcgtatt gccacctcgt gttccccgcg ccagcgggga taaaccgtta
     8761 ggcacagaaa aaaggctact cagcgaactg tgttccccgc gccagcgggg ataaaccgta
     8821 tcgaccccct ttctcacgca tcgccatcgt gtgttccccg cgccagcggg gataaaccgc
     8881 caaaaatgcg ccccatgcgc acaaattcgc gcgtgttccc cgcgccagcg gggataaacc
     8941 gccccgcaca cgtaaaggcg tcggcatgga tgcgtgttcc ccgcgccagc ggggataaac
     9001 ccccagcgcc agacgggaac acaattttaa agccgtgttc cccgcgccag cggggataaa
     9061 ccgttgtcgg ggatctgttc aaactgactc attaggtgtt ccccgcgcca gcggggataa
     9121 accgcagctc gcagcgctcg gaacgtggcg ctataggtgt tccccgcgcc agcggggata
     9181 aaccgtcgct attgccggta gtgtcgctga tagactcgtg ttccccgcgc cagcggggat
     9241 aaaccgcggc tatggaattt atggagaagt ttggttttgt gttccccgcg tcagcgggga
     9301 taaaccgggc gcactggatg cgatgatgga tatcacttag aattccccgc ccctgcggta
     9361 gaactcccag ctcccatttt caaacccatc aagacgcctt cgccagctcc ttcaccagcg
     9421 gtagcattat ccgcataaca tcacggcagc gacgttctat tcttccagga agtgccttat
     9481 caatatgctg ttgattatcc agtcttacgt catgccagct atttcccgca gggaatgcgg
     9541 ctgtttttgc gcgttgctga taaccatcct tattcccaag attccagtta gtcgcttcca
     9601 ccgaaagtac agcaatgccc gctttgtcga atatttctgc gtcattacaa cacccagtgc
     9661 ctttcggata atttttattc aaacccggat tggtcgttgc ggctattccg tgactgcgcg
     9721 caattgccag cgccctgtcg cgcgttaatt tccttactgc ttcaggggtt tttacaccgc
     9781 tgttgaaata caatttatcg ccaacaatta agttatcgag attaatcacc agcagcgtat
     9841 ttttcttttc ggtgtcactc atccgcttga gtaaattctc agcgcctaat ttcccttcct
     9901 cttcgccgct ggtcgccaca aatcgaatac catactcggt aggcgtattt ttcaggcgtt
     9961 ctgccaattc cagcatgaca cctaaacctg cggcgttatc atccattcct tgtaacgtca
    10021 gcccgccgag attggcatcg gcgtcagcat cgctcagcgg ggcgtaagta tccagatgcg
    10081 ccataatgat gatctgctgc ggcgctttgc cttcatgagc ggcaatcacc gtacttcctg
    10141 tcacgttatg ccagttcttg cgattatcgc gggcggtata aatataccga ctattaaatg
    10201 tccgaatatc actgcgataa cccatttgct gaaactgttg gcgaatataa tcggcagata
    10261 acatttctgc tggagttccg gtcatgcgtc ccggaaagaa agtagcaata tgtcgtgcct
    10321 gggtattagc aaaatcgcca ggtttaggtg acgaggcgtg tacggggaga ataaagcata
    10381 cgccgagcgc cagggcagcg gtacggtggc gcaatgcgga aaacatagtg agtccttaaa
    10441 taccatgcaa atttttttac cgccatagta tgaaactgcc gctgcgctaa aacaatttca
    10501 aatcttccta aacgcccgaa atccggtgcc ttaagcactt tttgatatta gctttgccaa
    10561 atcgttattc cgttaaggaa ctactcattc taattggtaa tttcattcgt tctcttacgc
    10621 tccctatagt cgaaacatct gatggcaaga aaatagcggt attgcaaagg aacggttatg
    10681 gatcaaaaac gacttactca cctgcggcaa ctggaggcgg aaagcatcca cattattcgc
    10741 gaggtggcgg cagaattctc aaatccggtg atgctctact ctatcggtaa agattccagc
    10801 gtcatgctgc atttggcgcg caaggcgttt tatccaggta cgctgccttt cccgttgctg
    10861 catgtcgata ccggctggaa attccgcgag atgtatgagt tccgcgatcg tactgctaaa
    10921 gcctacggct gcgaactgct ggtgcataaa aacccggaag gcgtggcgat ggggattaat
    10981 ccattcgtgc acggcagcgc gaaacatacc gatattatga aaactgaagg cctgaaacag
    11041 gcgctgaaca aatacggttt tgatgccgcc ttcggtggtg cgcgccgtga cgaagagaaa
    11101 tcccgcgcta aagagcgaat ttactctttc cgtgaccgct tccatcgctg ggatccgaaa
    11161 aatcagcgcc cggagctgtg gcacaactac aacgggcaaa ttaacaaagg cgaaagcatc
    11221 cgcgtcttcc cgctctctaa ctggaccgag caggatatct ggcaatacat ctggctggaa
    11281 aatatcgaca ttgttccgct atatctcgct gcggaacgtc cggttctgga acgcgacggt
    11341 atgttgatga tgattgatga caaccgtatc gacctgcaac cgggcgaagt gattaaaaaa
    11401 cggatggtgc gtttccgtac gctgggctgc tggccgctga ccggtgcggt ggagtcaaat
    11461 gcacaaacac tgccggaaat catcgaagag atgctggttt ccaccaccag tgaacgtcag
    11521 ggccgcgtga ttgaccgcga ccaggcgggg tctatggagc tgaaaaaacg tcaggggtat
    11581 ttttaagatg aacaccgcac ttgcacaaca aatcgccaat gaaggcggcg tcgaagcctg
    11641 gatgattgcg caacaacata aaagcctgct gcgttttctg acctgtggta gcgtcgatga
    11701 cggcaaaagt accctgattg gtcgcctgct gcacgatacc cgccaaatct acgaagatca
    11761 gctctcatcg ctgcataacg acagtaagcg tcacggcacc cagggcgaaa aactggatct
    11821 ggctctgctg gtggacggcc tgcaagctga gcgcgaacag ggcatcacta ttgatgtggc
    11881 ctaccgctat ttctctaccg agaagcgtaa atttattatc gccgacaccc ccgggcacga
    11941 gcagtatacc cgcaatatgg cgaccggcgc ctcaacgtgt gagctggcga tcttactgat
    12001 cgatgcccgt aaaggcgtgc tcgatcaaac ccgtcgtcac agttttatct ccacgctgct
    12061 ggggatcaaa catctggtcg tagcgatcaa caaaatggat ctggtggatt acagtgaaga
    12121 gacattcacc cgcattcgta aagactacct gactttcgcc gaacagttac ctggcaatct
    12181 ggatattcgc tttgtgccgc tctctgcgct ggaaggcgac aacgtggctt cgcaaagtga
    12241 aagtatgccg tggtacagcg gtccgacact gctcgaagtg ctggaaaccg tggagatcca
    12301 gcgagtggtg gatgctcagc caatgcgctt cccggtgcag tacgttaatc gcccgaatct
    12361 cgattttcgt ggttacgccg gaacgctggc atccggtcgc gtggaagtcg ggcaacgtgt
    12421 aaaagtgctg ccttctggtg tggaatcaaa cgtcgcgcgg atcgtgactt ttgatggtga
    12481 tcgcgaagaa gcctttgccg gagaagcgat caccctggtg ctgacggatg agatcgacat
    12541 cagccgtggc gatctgctgc tggcggcaga cgaagcgtta ccggcggtgc agagcgcgtc
    12601 ggtggatgtg gtatggatgg cggaacagcc gctttctcca gggcagagtt acgacatcaa
    12661 aattgccggt aagaagacgc gcgcgcgtgt tgatggcatt cgctatcagg ttgatattaa
    12721 taaccttacc cagcgtgaag ttgaaaacct gccactgaat gggatcggcc tcgtggatct
    12781 cacttttgac gagccgctgg tgttagatcg ttatcaacaa aatccggtga cgggtgggct
    12841 gatttttatc gatcgcctga gcaatgtgac cgtgggtgcc ggtatggtgc acgagccagt
    12901 tagccaggca actgctgcgc catctgaatt cagtgcattc gaactggaat tgaatgctct
    12961 ggttcgtcgc cactttccgc actggggcgc gcgcgatttg ctgggggata aataatggcg
    13021 ctgcatgacg aaaacgtcgt ctggcatagc catccggtca ctgtgcaaca acgcgagcta
    13081 caccacggtc atcgtggtgt agtgctgtgg tttaccggcc tctccgggtc cggtaaatca
    13141 acggtcgccg gggtgctgga ggaggcgtta cataaactcg gcgtcagtac gtatctgctg
    13201 gatggcgata atgttcgcca cggattatgc agcgatctcg gttttagcga tgccgatcgt
    13261 aaagagaata tccgtcgcgt cggtgaagtg gcgaatttga tggttgaagc cggactggta
    13321 gtgctgaccg catttatctc gccacaccgc gccgaacgcc agatggttcg cgaacgcgta
    13381 ggagaagggc gctttatcga agtgtttgtc gatacgccgc tggcgatttg cgaagcccgc
    13441 gatccaaaag gcttatataa gaaagcgcgt gccggtgaac tgcgcaactt tacgggaata
    13501 gattctgttt acgaagcgcc tgaatcggca gaaattcatc tcaatggtga acaattagta
    13561 acaaatttgg tacagcaatt attagatctg ttgagacaga acgatattat cagatcctga
    13621 gacaccaccg ggtttccatg cccggttcgt caaagtaaca ggatcaaata tgcgtaatag
    13681 ccataacatt acactaacaa ataacgacag ccttactgag gatgaagaaa ccacatggtc
    13741 actgcctggt gccgtggtcg gttttatctc ctggttattt gcgctggcga tgccgatgtt
    13801 gatttatggc tctaacacgc tgttcttctt tatctacacc tggcctttct ttctggcgct
    13861 gatgcccgtc gcggtagtgg tggggattgc gctgcattca ttgatggacg gaaagctacg
    13921 ctacagtatt gttttcaccc tggtgacagt aggcattatg tttggcgcac tgtttatgtg
    13981 gctactgggc taatttgtac tttcccgtct cctctgttca taattcaaac cgtaactaat
    14041 aatgagatta tgttctgcac gccctgggta tacgtaacaa tggacaaatg tggtacattt
    14101 gcccgcgttg tcgcggtatc cccaacagag gatgtagagt cgtcttcgga tgcatgggat
    14161 gatgatgccg tttttcaggg ggcaggatgg gtaaactaac gctgctgttg ctggctattc
    14221 tggtctggct acagtattcg ctgtggttcg gtaagaacgg tatacatgac tatacccgcg
    14281 tcaatgatga tgtggcggca cagcaagcta caaacgcgaa acttaaagcg cgaaacgatc
    14341 aactttttgc cgaaattgac gatctcaatg gcggccagga ggcgctcgaa gagcgtgcgc
    14401 gtaatgaact cagcatgacc aggccgggcg aaacttttta tcgtctggtg cctgacgcgt
    14461 cgaagcgcgc acagtctgcg gggcaaaaca atcgataaat cagcccggga attaacatgg
    14521 caaccactca tttggatgtt tgcgccgtgg ttccggcggc cggatttggc cgtcgaatgc
    14581 aaacggaatg tcctaagcaa tatctctcaa tcggtaatca aaccattctt gaacactcgg
    14641 tgcatgcgct gctggcgcat ccccgggtga aacgtgtcgt cattgccata agtcctggcg
    14701 atagccgttt tgcacaactt cctctggcga atcatccgca aatcaccgtt gtagatggcg
    14761 gtgatgagcg tgccgattcc gtgctggcag gtttgaaagc cgctggcgac gcgcagtggg
    14821 tattggtgca tgacgccgct cgtccttgtc tgcatcagga tgacctcgcg cgattgttgg
    14881 cgttgagcga aaccagccgc acgggaggga tcctagccgc accagtgcgc gatacgatga
    14941 aacgtgccga accgggcaaa aatgccattg ctcataccgt tgatcgcaac ggcttatggc
    15001 acgcgctgac gccgcaattt ttccctcgtg agctgttaca tgactgtctg acgcgcgctc
    15061 taaatgaagg cgcgactatt accgacgaag cctcggcgct ggaatattgc ggattccatc
    15121 ctcagttggt cgaaggccgt gcggataaca ttaaagtcac gcgcccggaa gatttggcac
    15181 tggccgagtt ttacctcacc cgaaccatcc atcaggagaa tacataatgc gaattggaca
    15241 cggttttgac gtacatgcct ttggcggtga aggcccaatt atcattggtg gcgtacgcat
    15301 tccttacgaa aaaggattgc tggcgcattc tgatggcgac gtggcgctcc atgcgttgac
    15361 cgatgcattg cttggcgcgg cggcgctggg ggatatcggc aagctgttcc cggataccga
    15421 tccggcattt aaaggtgccg acagccgcga gctgctacgc gaagcctggc gtcgtattca
    15481 ggcgaagggt tataccctgg gcaacgtcga tgtcactatc atcgctcagg caccgaagat
    15541 gttgccgcac attccacaaa tgcgcgtgtt tattgccgaa gatctcggct gccatatgga
    15601 tgatgttaac gtgaaagcca ctactacgga aaaacttgga tttaccggac gtggggaagg
    15661 gattgcctgt gaagcggtgg cgctactcat taaggcaaca aaatgattga gtttgataat
    15721 ctcacttacc tccacggtaa accgcaaggc accgggctgc tgaaagccaa tccggaagac
    15781 tttgtggtgg tggaagattt gggctttgag cctgatggtg aaggtgagca tattctggtt
    15841 agaatcctca aaaacggctg caatacccgt tttgtggcgg atgcactggc gaaattcctg
    15901 aaaattcatg cccgtgaagt cagcttcgct gggcaaaaag acaaacatgc tgttacggaa
    15961 cagtggttat gcgctcgcgt gccaggcaag gaaatgcccg atctgagcgc ctttcaactg
    16021 gaaggctgcc aggtgctgga gtatgcgcgg cacaagcgca agctgcgttt aggcgcgctg
    16081 aaaggtaacg cctttaccct ggttctgcgc gaagtgagca atcgcgatga cgttgaacaa
    16141 cgtctgatcg atatttgcgt aaaaggtgta ccgaactact tcggtgccca acgttttggg
    16201 attggcggta gcaacttgca gggcgcgctg cgctgggcgc aaaccaatac tccggtgcgc
    16261 gatcgcaata aacggagttt ttggttgtcg gcagcccgca gtgcgttgtt taatcagatt
    16321 gttgctgagc gcctcaaaaa agcagacgtt aatcaagttg ttgacggcga tgcgctacaa
    16381 ttagccggac gtggtagctg gtttgtagca accaccgaag aactggcgga attacagcgt
    16441 cgcgtcaacg ataaagagct gatgataacc gccgcattgc cgggcagtgg cgaatgggga
    16501 actcagcgtg aagcgctggc attcgaaaag gcagctgtcg ccgcagaaac tgaattacaa
    16561 gctttactgg tgcgcgaaaa agttgaagcc gcgcgcagag cgatgttgct gtatccgcaa
    16621 caattaagct ggaattggtg ggatgacgtc accgtagaga tccgtttctg gcttccggcg
    16681 ggtagttttg caaccagcgt tgtcagggaa cttatcaaca caacaggtga ttatgcgcat
    16741 attgctgagt aatgatgacg gggtacatgc acccggtata caaacgctgg cgaaagcctt
    16801 gcgtgagttt gctgacgttc aggtggtcgc ccccgatcgt aaccgcagcg gcgcttcaaa
    16861 ttctctgaca ctggaatcct ccctgcgcac gtttaccttt gaaaatggtg atattgctgt
    16921 gcaaatggga accccgaccg attgcgtcta tcttggcgtg aatgctctga tgcgtccgcg
    16981 cccggacatt gttgtgtccg gaattaacgc cgggccgaat ctgggggatg acgttattta
    17041 ttccggtacg gtagccgccg cgatggaagg ccgtcattta ggttttccgg cgcttgccgt
    17101 ctcgcttgac gggcataaac attacgacac tgccgcggcg gtaacctgtt caattttgcg
    17161 cgcactgtgt aaagagccgt tgcgcaccgg gcgtattctt aatattaacg ttccggattt
    17221 acccttggat caaatcaaag gtattcgcgt gacgcgctgc ggtacacgac atccggcaga
    17281 tcaggtgatc ccgcagcaag atccgcgcgg caatacgctg tactggattg gcccgccggg
    17341 cggtaaatgt gatgccggtc cggggaccga ttttgctgcg gtagatgagg gctatgtctc
    17401 catcacgccg ctgcatgtgg atttaactgc gcatagcgcg caagatgtgg tttcagactg
    17461 gttaaacagc gtgggagttg gcacgcaatg gtaagcagac gcgtacaagc acttctggat
    17521 caattacgtg cgcaaggtat tcaggatgag caggtgctga atgcacttgc cgccgtgccg
    17581 cgtgaaaaat tcgttgatga agcgtttgaa caaaaagcct gggacaatat cgccttgccg
    17641 ataggtcagg ggcagacaat ttcgcagccg tatatggtgg cgcgaatgac cgaattactc
    17701 gagctgacgc cgcagtcgcg ggtgctggaa attggcactg gttcgggata tcaaacggca
    17761 atcctggcgc atcttgtcca gcatgtttgc tcggtcgaac ggattaaagg tttgcagtgg
    17821 caggcgcgtc gccgcctgaa aaatcttgat ttacataatg tttcaacccg tcatggcgat
    17881 ggatggcaag gttggcaggc acgcgcgccg tttgacgcta tcattgttac ggcggcaccg
    17941 ccggaaattc caactgcgct aatgacgcag ctggacgaag gcgggattct cgtcttaccc
    18001 gtaggggagg agcaccagta tttgaaacgg gtgcgtcgtc ggggaggcga atttattatc
    18061 gataccgtgg aggccgtgcg ctttgtccct ttagtgaagg gtgagctggc ttaaaacgtg
    18121 aggaaatacc tggatttttc ctggttattt tgccgcaggt cagcgtatcg tgaacatctt
    18181 ttccagtgtt cagtagggtg ccttgcacgg taattatgtc actggttatt aaccaatttt
    18241 tcctggggga taaatgagcg cgggaagccc aaaattcacc gttcgccgca ttgcggcttt
    18301 gtcactggtt tcgctatggc tggcaggctg ttctgacact tcaaatccac cggcaccggt
    18361 cagctccgtt aatggcaatg cgcctgcaaa taccaattct ggtatgttga ttacgccgcc
    18421 gccgaaaatg gggacgacgt ctacagccca gcaaccgcaa attcagccgg tacagcagcc
    18481 acaaattcag gctactcaac aaccgcaaat ccagccagtg cagccagtag ctcagcagcc
    18541 ggtacagatg gaaaacggac gcatcgtcta taaccgtcag tatgggaaca ttccgaaagg
    18601 cagttatagc ggcagtacct ataccgtgaa aaaaggcgac acacttttct atatcgcctg
    18661 gattactggc aacgatttcc gtgaccttgc tcagcgcaac aatattcagg caccatacgc
    18721 gctgaacgtt ggtcagacct tgcaggtggg taatgcttcc ggtacgccaa tcactggcgg
    18781 aaatgccatt acccaggccg acgcagcaga gcaaggagtt gtgatcaagc ctgcacaaaa
    18841 ttccaccgtt gctgttgcgt cgcaaccgac aattacgtat tctgaatctt cgggtgaaca
    18901 gagtgctaac aaaatgttgc cgaacaacaa gccagctgcg accacggtca cagcgcctgt
    18961 aacggtacca acagcaagca caaccgagcc aactgtcagc agtacatcaa ccagtacgcc
    19021 tatctccacc tggcgctggc cgactgaggg caaagtgatc gaaacctttg gcgcttctga
    19081 ggggggcaac aaggggattg atatcgcagg cagcaaagga caggcaatta tcgcgaccgc
    19141 agatggccgc gttgtttatg ctggtaacgc gctgcgcggc tacggtaatc tgattatcat
    19201 caaacataat gatgattacc tgagtgccta cgcccataac gacacaatgc tggtccggga
    19261 acaacaagaa gtgaaggcgg ggcaaaaaat agcaaccatg ggtagcaccg gaaccagttc
    19321 aacacgcttg cattttgaaa ttcgttacaa ggggaaatcc gtaaacccgc tgcgttattt
    19381 gccgcagcga taaatcggcg gaaccatgct tttgcttgaa tgttccgtca agggatcacg
    19441 ggtaggagcc accttatgag tcagaatacg ctgaaagttc atgatttaaa tgaagatgcg
    19501 gaatttgatg agaacggagt tgaggttttt gacgaaaagg ccttagtaga agaggaaccc
    19561 agtgataacg atttggccga agaggaactg ttatcgcagg gagccacaca gcgtgtgttg
    19621 gacgcgactc agctttacct tggtgagatt ggttattcac cactgttaac ggccgaagaa
    19681 gaagtttatt ttgcgcgtcg cgcactgcgt ggagatgtcg cctctcgccg ccggatgatc
    19741 gagagtaact tgcgtctggt ggtaaaaatt gcccgccgtt atggcaatcg tggtctggcg
    19801 ttgctggacc ttatcgaaga gggcaacctg gggctgatcc gcgcggtaga gaagtttgac
    19861 ccggaacgtg gtttccgctt ctcaacatac gcaacctggt ggattcgcca gacgattgaa
    19921 cgggcgatta tgaaccaaac ccgtactatt cgtttgccga ttcacatcgt aaaggagctg
    19981 aacgtttacc tgcgaaccgc acgtgagttg tcccataagc tggaccatga accaagtgcg
    20041 gaagagatcg cagagcaact ggataagcca gttgatgacg tcagccgtat gcttcgtctt
    20101 aacgagcgca ttacctcggt agacaccccg ctgggtggtg attccgaaaa agcgttgctg
    20161 gacatcctgg ccgatgaaaa agagaacggt ccggaagata ccacgcaaga tgacgatatg
    20221 aagcagagca tcgtcaaatg gctgttcgag ctgaacgcca aacagcgtga agtgctggca
    20281 cgtcgattcg gtttgctggg gtacgaagcg gcaacactgg aagatgtagg tcgtgaaatt
    20341 ggcctcaccc gtgaacgtgt tcgccagatt caggttgaag gcctgcgccg tttgcgcgaa
    20401 atcctgcaaa cgcaggggct gaatatcgaa gcgctgttcc gcgagtaagt aagcatctgt
    20461 cagaaaggcc agtctcaagc gaggctggcc ttttttcttt cggttggtga gtcggtgtat
    20521 ttgtagtctg gataagacgc gatagcgtcg catccggaaa tttgccccct atgcgttcat
    20581 catcttgcgc accagctgca taaacagctc ctgctcttct ccactcaaac gccccaaaaa
    20641 ttcctcatcc acgctgtcac caatgggtat cgccgcagca agtatctttt cgccttcggc
    20701 agtcaaccag acaaagcgtc gccgcttatc agcggggtca tgttcacgtc tgactaagcc
    20761 acgattttcc attcttgcca acatttctgc taacgttgct ttggtgctga cagctgcttc
    20821 tatcagtgcc acctgttcga taccaggttt atcagcaatg gcgcgcatca ccgcgtactg
    20881 tggtttggtc aggtcaggta actcgtgctg ccagcgagcc gtgtgctgct gaaaaagctg
    20941 tcgtaactga tggaacgctt tatttcgtaa cgccatgtaa actccgggct aattctctgt
    21001 tgctatcata gcggtttttt agtgacgaag aagatgttgt tacttttcaa tccttgccgc
    21061 tgtggaaatg aaggagtatg ttaataataa cgttcgtata cgaacaatta agaggataag
    21121 caatgaaact gatcgtcggg atgacagggg ctaccggtgc gcctcttggt gtggcattac
    21181 tgcaagcgct gcgggagatg ccgaatgtcg agactcatct ggtgatgtcg aagtgggcga
    21241 aaaccaccat tgaactggaa acgccttaca gcgctcgcga tgttgctgcc ctcgcagact
    21301 tcagccataa cccggcggat caggcggcga tcatctcatc cggttctttt cgtaccgacg
    21361 gcatgatcgt tattccgtgc agtatgaaaa cgctcgccgg tatccgcgct ggttacgccg
    21421 atggcctggt agggcgcgcg gcggacgtcg tgctcaaaga aggccgcaaa ctggtgctgg
    21481 tgccgcgaga aatgccgctt agcaccatcc atctcgaaaa tatgctcgca ctttcacgca
    21541 tgggcgtggc gatggtgccg ccgatgcctg ccttttataa ccatcccgaa acggtagatg
    21601 acattgtcca ccatgtggta gcccgcgtgc tggatcaatt tggcctcgaa catccccacg
    21661 ccaggcgctg gcaaggattg ccgcaggccc ggaatttttc tcaggagaat gaataatggc
    21721 atttgatgat ttacgcagct ttttacaggc gcttgatgac cacggccagt tactgaaaat
    21781 cagcgaagag gtgaacgctg agccggatct ggcagcagca gctaacgcca ccgggcgtat
    21841 cggcgacggc gcgcccgcgc tgtggtttga taatattcgc ggctttaccg atgcccgcgt
    21901 gacgatgaat accatcggtt cctggcagaa ccacgcgatt tcccttggcc tgccaccaaa
    21961 caccccggtc aaaaagcaga ttgatgagtt tatccgccgc tgggataact tcccgattgc
    22021 cccggagcgc cgcgccaatc cagcctgggc gcagaacacc gt
//
LOCUS       DAZUDJ010000075        21933 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.075, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000075 DAZUDJ010000000
VERSION     DAZUDJ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21933
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.075"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            167..943
                     /gene="exuR"
                     /locus_tag="ACHY1N_003946"
     CDS             167..943
                     /gene="exuR"
                     /locus_tag="ACHY1N_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ExuR"
                     /protein_id="HFS4046158.1"
                     /translation="MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNV
                     SRTVVREAIIMLEVEGYVEVRKGSGIHVVSNQPRHQQAADNNMEFANYGPFELLQARQ
                     LIESNIAEFAATQVTKQDIMKLMAIQEQARGEQCFRDSEWDLQFHIQVALATQNSALA
                     AIVEKMWTQRSHNPYWKKLHEHIDSRTVDNWCDDHDQILKALIRKDPHAAKLAMWQHL
                     ENTKIMLFNETSDDFEFNADRYLFAENPVVHLDTATSGSK"
     gene            1183..1266
                     /gene="yqiM"
                     /locus_tag="ACHY1N_003947"
     CDS             1183..1266
                     /gene="yqiM"
                     /locus_tag="ACHY1N_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YqiM"
                     /protein_id="HFS4046159.1"
                     /translation="MLMYQTRRTYQNSNNIAVVHLLKPAWR"
     gene            1288..1950
                     /gene="yqjA"
                     /locus_tag="ACHY1N_003948"
     CDS             1288..1950
                     /gene="yqjA"
                     /locus_tag="ACHY1N_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family general envelope maintenance protein
                     YqjA"
                     /protein_id="HFS4046160.1"
                     /translation="MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLP
                     AAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMS
                     GLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGN
                     RG"
     gene            1954..2337
                     /gene="mzrA"
                     /locus_tag="ACHY1N_003949"
     CDS             1954..2337
                     /gene="mzrA"
                     /locus_tag="ACHY1N_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HFS4046161.1"
                     /translation="MQIPRMSLRQLAWSGTVLLLVGTLLLAWSAVRQQESTLAIRAVH
                     QGTTMPDGFSIWHHLDAHGIPFKSITPKNDTLLITFDSSDQSAAAKAVLDRTLPHGYI
                     IAQQDNNSQAMQWLTRLRDNSHRFG"
     gene            2484..2852
                     /gene="yqjC"
                     /locus_tag="ACHY1N_003950"
     CDS             2484..2852
                     /gene="yqjC"
                     /locus_tag="ACHY1N_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 family protein YqjC"
                     /protein_id="HFS4046162.1"
                     /translation="MKYRIALAVSLFALSAGSYATTLCQEKEQNILKEISYAEKHQNQ
                     NRIDGLNKALSEVRANCSDSQLRADHHKKIAKQKDEVAERQQDLAEAKQKGDADKIAK
                     RERKLAEAQEELKKLEARDY"
     gene            2890..3195
                     /gene="yqjD"
                     /locus_tag="ACHY1N_003951"
     CDS             2890..3195
                     /gene="yqjD"
                     /locus_tag="ACHY1N_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqjD family protein"
                     /protein_id="HFS4046163.1"
                     /translation="MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAE
                     QALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR"
     gene            3198..3602
                     /gene="yqjE"
                     /locus_tag="ACHY1N_003952"
     CDS             3198..3602
                     /gene="yqjE"
                     /locus_tag="ACHY1N_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFS4046164.1"
                     /translation="MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEK
                     ANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIW
                     TLRKSRKSTLLRHTRHELANDRQLLEEESREQ"
     gene            3592..3891
                     /gene="yqjK"
                     /locus_tag="ACHY1N_003953"
     CDS             3592..3891
                     /gene="yqjK"
                     /locus_tag="ACHY1N_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK-like family protein"
                     /protein_id="HFS4046165.1"
                     /translation="MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWN
                     MLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG"
     gene            4077..4469
                     /gene="yqjF"
                     /locus_tag="ACHY1N_003954"
     CDS             4077..4469
                     /gene="yqjF"
                     /locus_tag="ACHY1N_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008503138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HFS4046166.1"
                     /translation="MKKLEDVGVLVARILMPILFITAGWGKITAYSGTQQYMEAMGVP
                     GFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKN
                     LTISGGFLLLAITGPGAYSIDRLLNKKW"
     gene            4539..5525
                     /gene="yqjG"
                     /locus_tag="ACHY1N_003955"
     CDS             4539..5525
                     /gene="yqjG"
                     /locus_tag="ACHY1N_003955"
                     /EC_number="1.8.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionyl-hydroquinone reductase YqjG"
                     /protein_id="HFS4046167.1"
                     /translation="MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTG
                     TGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSF
                     PGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAF
                     DALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRD
                     IYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG"
     gene            5818..6183
                     /gene="yhaH"
                     /locus_tag="ACHY1N_003956"
     CDS             5818..6183
                     /gene="yhaH"
                     /locus_tag="ACHY1N_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HFS4046168.1"
                     /translation="MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKML
                     GWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFN
                     CQAGTPGENRFGPDPKLEP"
     gene            6425..6781
                     /locus_tag="ACHY1N_003957"
     CDS             6425..6781
                     /locus_tag="ACHY1N_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HFS4046169.1"
                     /translation="MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLIL
                     GLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEG
                     NSGSNRYGNDPKFGSN"
     gene            complement(6832..7728)
                     /gene="yhaJ"
                     /locus_tag="ACHY1N_003958"
     CDS             complement(6832..7728)
                     /gene="yhaJ"
                     /locus_tag="ACHY1N_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YhaJ"
                     /protein_id="HFS4046170.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIV
                     TEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKSWCLREIPKLFSGK"
     gene            7833..8534
                     /gene="yhaK"
                     /locus_tag="ACHY1N_003959"
     CDS             7833..8534
                     /gene="yhaK"
                     /locus_tag="ACHY1N_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HFS4046171.1"
                     /translation="MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLN
                     QEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYS
                     EHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVW
                     LHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITL
                     VADSPLRALLIDLPV"
     gene            8557..8721
                     /gene="yhaL"
                     /locus_tag="ACHY1N_003960"
     CDS             8557..8721
                     /gene="yhaL"
                     /locus_tag="ACHY1N_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312016.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YhaL"
                     /protein_id="HFS4046172.1"
                     /translation="MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAE
                     TRLAEDEATA"
     gene            complement(8933..10243)
                     /gene="cyuA"
                     /locus_tag="ACHY1N_003961"
     CDS             complement(8933..10243)
                     /gene="cyuA"
                     /locus_tag="ACHY1N_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfidase"
                     /protein_id="HFS4046173.1"
                     /translation="MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAEL
                     EGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQ
                     AIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNG
                     VVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEG
                     LSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAA
                     GMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR"
     gene            complement(10271..11602)
                     /gene="cyuP"
                     /locus_tag="ACHY1N_003962"
     CDS             complement(10271..11602)
                     /gene="cyuP"
                     /locus_tag="ACHY1N_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026203.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4046174.1"
                     /translation="MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMS
                     IGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSV
                     ISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGL
                     VLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLV
                     KNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFF
                     YAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFG
                     VYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTS
                     ICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS"
     gene            complement(11877..13241)
                     /gene="tdcG"
                     /locus_tag="ACHY1N_003963"
     CDS             complement(11877..13241)
                     /gene="tdcG"
                     /locus_tag="ACHY1N_003963"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HFS4046175.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSH
                     IVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGA
                     HIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS
                     HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHD
                     GIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISG
                     AEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            complement(13313..13702)
                     /gene="tdcF"
                     /locus_tag="ACHY1N_003964"
     CDS             complement(13313..13702)
                     /gene="tdcF"
                     /locus_tag="ACHY1N_003964"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enamine/imine deaminase"
                     /protein_id="HFS4046176.1"
                     /translation="MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPA
                     DVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATY
                     PTRSCVQVARLPKDVKLEIEAIAVRSA"
     gene            complement(13716..16010)
                     /gene="tdcE"
                     /locus_tag="ACHY1N_003965"
     CDS             complement(13716..16010)
                     /gene="tdcE"
                     /locus_tag="ACHY1N_003965"
                     /EC_number="2.3.1.-"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-ketobutyrate formate-lyase/pyruvate
                     formate-lyase"
                     /protein_id="HFS4046177.1"
                     /translation="MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGD
                     ESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIV
                     GLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPD
                     MLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDL
                     EATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDG
                     EYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAL"
     gene            complement(16044..17252)
                     /gene="tdcD"
                     /locus_tag="ACHY1N_003966"
     CDS             complement(16044..17252)
                     /gene="tdcD"
                     /locus_tag="ACHY1N_003966"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0006082 - organic acid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HFS4046178.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAF
                     LSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITD
                     EVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
                     WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLI
                     RRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHL
                     GKVNAPAEFA"
     gene            complement(17278..18609)
                     /gene="tdcC"
                     /locus_tag="ACHY1N_003967"
     CDS             complement(17278..18609)
                     /gene="tdcC"
                     /locus_tag="ACHY1N_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
                     /protein_id="HFS4046179.1"
                     /translation="MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRA
                     GFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITF
                     LYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLM
                     VKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIM
                     VFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLF
                     TLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGH
                     YLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAM
                     GAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF"
     gene            complement(18631..19620)
                     /gene="tdcB"
                     /locus_tag="ACHY1N_003968"
     CDS             complement(18631..19620)
                     /gene="tdcB"
                     /locus_tag="ACHY1N_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HFS4046180.1"
                     /translation="MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLIDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAA
                     SFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA"
     gene            complement(19719..20657)
                     /gene="tdcA"
                     /locus_tag="ACHY1N_003969"
     CDS             complement(19719..20657)
                     /gene="tdcA"
                     /locus_tag="ACHY1N_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HFS4046181.1"
                     /translation="MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIIND
                     IEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFG
                     FPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKL
                     QDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAV
                     WSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG"
     gene            20972..21190
                     /gene="tdcR"
                     /locus_tag="ACHY1N_003970"
     CDS             20972..21190
                     /gene="tdcR"
                     /locus_tag="ACHY1N_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417589.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator TdcR"
                     /protein_id="HFS4046182.1"
                     /translation="MSKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNT
                     GIDHLEQLINVNFFSSDRTSFCECNRFP"
     gene            21446..>21933
                     /gene="yhaB"
                     /locus_tag="ACHY1N_003971"
     CDS             21446..>21933
                     /gene="yhaB"
                     /locus_tag="ACHY1N_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312027.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YhaB"
                     /protein_id="HFS4046183.1"
                     /translation="MKGFPIAHIFHPSIPPMHAVVNNHNRNIDYWTVKRKFAEIVSTN
                     DVNKIYSISNELRRVLSAITALNFYQGDVPSVMIRIQPENMSPFIIDISTGEHDDYII
                     QTLDVGTFAPFGEQCTCSAVNKKELECIKETISKYCAKFTRKEAILTPPAHFNKTSIT
                     SD"
BASE COUNT         5756 a         5626 c         5133 g         5418 t
ORIGIN      
        1 tttagtagct ttcacaatga cgatacttat tttttaggaa tttataaata ttcacaatat
       61 taattcaata cattaattca atcaccaaat ttatatatga ccaatggcat acccatgaat
      121 aaagtggtat gataacttcg tccgcattcc actccgggag acgcatatgg aaatcactga
      181 accacgccgt ttgtatcaac aacttgccgc tgacctgaaa gagcgcatcg aacagggcgt
      241 ctatctggta ggtgataaac tgcctgcaga acgctttatt gccgatgaaa agaacgtcag
      301 ccgtacggta gttcgtgaag ccatcatcat gctggaagtt gaaggctatg tcgaagtgcg
      361 taaaggttca ggtattcatg tggtttccaa ccagccgcgc catcagcagg cggctgacaa
      421 taatatggaa ttcgccaatt acggtccgtt tgagttgctt caggctcgcc agctcatcga
      481 aagtaatatt gccgagttcg cggcaactca ggtaacgaaa caagacatca tgaaactgat
      541 ggccattcag gaacaggcgc gcggcgaaca atgcttccgt gattccgagt gggatttaca
      601 gttccacatt caggtagccc tggcgacgca gaactccgcc ctggcggcca tcgttgaaaa
      661 aatgtggacc caacgtagcc ataacccgta ctggaaaaaa ctgcacgaac acattgattc
      721 ccgtaccgtc gataactggt gtgatgacca cgatcaaatc ctcaaggcgc tgattcgcaa
      781 agatcctcat gctgctaagc tggcaatgtg gcagcacctg gaaaacacca agatcatgtt
      841 attcaacgaa accagcgacg acttcgagtt caatgccgac cgctatctgt tcgccgaaaa
      901 cccggtagtg catctcgata cggccaccag tggcagtaaa tgaaactcct gtccgacagg
      961 cgctgcgacg cgcctgtttg tctcgtcggt aagcgaaaag tataaagtgt cagcctgtgt
     1021 aaatcctctc gccaccctcc cctgcattca gcaaaatcag actccacgga catgtaattt
     1081 tgataacgaa caacgttgac ctttgttaca attagattca atttgaattt atgtttttga
     1141 atgctttctt atctcacgat ttaacaggga atagttcagg ctgtgttgat gtatcaaacc
     1201 cgcagaacat accaaaacag caataacatt gcggtagtgc atcttttaaa accagcgtgg
     1261 cgttaaccga ttcaccagga ataatgaatg gaacttttga cccaattgct gcaagccctg
     1321 tgggcgcagg attttgaaac cctggccaat ccatcgatga ttggcatgtt gtattttgtc
     1381 ttgtttgtaa ttttgttcct tgaaaacggc ttgcttccag cggccttttt accgggcgac
     1441 agtttactgg tattggtcgg cgtgttgatt gcgaaaggcg cgatgggtta cccgcaaacg
     1501 attctgctgc tgaccgttgc cgccagcctc ggctgctggg tcagctatat tcaggggcga
     1561 tggctgggca atacccgcac cgtacaaaac tggctatctc atttacccgc gcattatcat
     1621 caacgcgcac accatctttt tcataaacac ggtttatcgg cgctgttaat tggtcgcttt
     1681 attgcgtttg tcagaacact gctgccgacg attgccgggt tatcagggct gaataacgcg
     1741 cgctttcagt ttttcaactg gatgagcggt ctgctgtggg tattgatcct gacaactctg
     1801 ggttacatgc tcggcaaaac gccggtattt ttaaagtacg aggaccagct gatgtcatgc
     1861 ctgatgctgc tcccggtggt gctgctggtg tttggcctgg caggttctct ggtcgtgtta
     1921 tggaaaaaga aatatggaaa tcgggggtaa gggatgcaaa tacctcgcat gtcgcttcgc
     1981 cagctagcct ggtccggcac tgttttactt ctggtcggca cgctgttgct ggcctggtcc
     2041 gcggttcgcc agcaagagtc tacgctggcg attcgtgccg ttcatcaagg cacaacgatg
     2101 ccagacggtt tttcgatctg gcatcacctt gacgctcatg gcattccttt caaaagtatc
     2161 acccccaaaa acgacactct gttaattaca tttgactcca gcgaccagag cgccgccgca
     2221 aaagcggtcc tcgacagaac attgccccat ggctacatca ttgcgcagca ggacaataac
     2281 agtcaggcta tgcagtggct gacccggtta cgggataact ctcatcgctt cggataactt
     2341 cctgttatcc gaaacatatc actcactttg gtgatttcac cgtaactgtc tatgattaat
     2401 gaggcggtgg ttaacactac cgcttcgttg tctggacaat cgttcctttg taataggtcc
     2461 gaatcacaat ggaaggttca agaatgaaat accgcatcgc tttagctgtt tctctctttg
     2521 ctcttagtgc cggtagttat gccactaccc tgtgtcagga aaaggagcaa aatatcctta
     2581 aggagatcag ctatgccgaa aaacaccaaa accagaatcg tattgacggt ctgaataaag
     2641 ccctgagtga agtccgggcc aactgttcag atagccagct gcgtgccgat catcacaaga
     2701 aaatcgcaaa gcagaaagat gaggtggcgg aacgccagca agatttagcc gaggcgaagc
     2761 aaaaaggcga tgccgataag attgccaaac gcgaacggaa actggcagaa gcgcaggaag
     2821 agctgaaaaa gctggaagcg cgcgactact aactcacaat agtcactact tactcacctg
     2881 gagaaaacta tgtcgaaaga acacactacg gaacatctgc gtgctgagtt gaaatccctt
     2941 tccgatacgc tggaagaggt gcttagctca tctggcgaga agtcgaaaga agagttgagt
     3001 aagattcgta gcaaagcgga gcaggcactg aaacagagcc gttatcgcct gggtgaaacc
     3061 ggtgatgcca tcgccaaaca aacccgtgtc gcggcggcgc gtgctgatga gtatgtgcgt
     3121 gaaaatccgt ggaccggcgt gggaattggc gctgcaatcg gtgtagtgct cggcgttctg
     3181 ctgtcgcgtc gttaattatg gcggacactc atcacgcgca agggcccggt aaaagcgttc
     3241 tgggcatcgg gcagcgaatt gtttccatca tggttgaaat ggtggaaaca cgtctgcggc
     3301 tggcggtggt ggagctggaa gaggaaaaag ctaatctctt tcaactttta ctgatgctgg
     3361 gcctgacgat gcttttcgct gcatttggtc ttatgagcct gatggtgcta attatttggg
     3421 cggttgatcc gcaatatcgc ctgaatgcga tgattgccac caccgtggtg ttgctgctac
     3481 tggcactgat tggcggtatc tggacgttac gtaaatcgcg taaatccacc ttgctgcgcc
     3541 atacacgcca tgagctggca aacgatcggc aactgctcga ggaggagtcc cgtgagcagt
     3601 aaagtcgaac gtgaacgacg taaggcgcaa ctgcttagcc agatccagca acaacggctg
     3661 gatctttccg ccagtcgtcg tgaatggctg gaggcaacag gcgcttacga tcgtcgctgg
     3721 aatatgctgc taagtctgcg ctcctgggcg ctggttggca gtagcgtgat ggcgatctgg
     3781 acgattcgcc atcctaatat gctggtccgc tgggccagac gcggttttgg cgtatggagc
     3841 gcctggcgtc tggtaaaaac gaccctcaag cagcaacagc ttcgcggtta acttccctct
     3901 ggccggagca attccggcct tatccctcaa attttttgaa gatttttgac agttttcctt
     3961 gctaacaatc atcattcacc acgtttatga ttctctccat cgacagcaac gacgctaata
     4021 ccgcgccctt gcacaaaaaa acaatcagca gcctgagtgg cgcagtggag agtatgatga
     4081 aaaaattaga agatgttggt gtactggtag cgcgcatttt aatgccgatt ctgtttatta
     4141 ccgcaggctg gggaaaaatc accgcttact ctggtaccca acaatatatg gaagcaatgg
     4201 gtgtcccggg ttttatgctg ccgctggtga ttctgcttga gttcggtggt ggtctggcaa
     4261 tcctgttcgg tttcctgact cgcaccacag ccctgtttac tgcgggcttt acgctgctga
     4321 cggcattttt atttcacagc aactttgctg aaggcgtcaa ctcgctgatg ttcatgaaaa
     4381 acctgacaat ttctggcgga ttcctgctgc tggcaattac cggtccgggc gcgtatagca
     4441 tcgaccgcct gctgaataaa aagtggtaag cacgcgctat acttaacgat aaaaaacgag
     4501 gaggaagctc ctcgtttttg ctattggagg agagaaaaat gggtcaactg attgacggcg
     4561 tctggcatga cacctggtac gataccaaat ctaccggcgg taaatttcaa cgttcagctt
     4621 ccgcatttcg taactggctc actgccgatg gcgcacctgg ccccactggc acaggcggtt
     4681 ttatcgcaga gaaagatcgt tatcatctct atgtttcact cgcctgcccg tgggcgcacc
     4741 gcacgctgat catgcgcaaa ctcaaaggac tggaaccgtt tatttccgtt tccgtagtga
     4801 acccgctgat gctggaaaac ggctggacct ttgatgacag ttttccggga gcaaccggag
     4861 atacgctcta tcaacatgaa tttctgtatc agctttatct ccacgccgat ccacactaca
     4921 gcggacgagt tactgttccc gtgctgtggg acaaaaagaa ccacaccatc gtcagcaacg
     4981 aatcagcaga aatcatccgc atgtttaata ccgcgtttga tgcgctgggc gcgaaagcgg
     5041 gtgattacta cccaccagcc ctgcaaacga aaattgacga acttaacggc tggatttatg
     5101 acaccgttaa caacggcgtg tataaagctg gttttgccac cagccagcaa gcctacgacg
     5161 aggcggtggc gaaagtgttt gaatcgctgg cgcgactgga gcagatttta ggccagcatc
     5221 gttacctgac cggcaaccag ctaaccgaag ccgatattcg cctgtggacc acgctggtcc
     5281 gttttgatcc agtgtatgtg acccacttca agtgtgataa gcaccgcatc agcgattacc
     5341 ttaatctgta tggcttcctg cgtgatatct accagatgcc gggaattgcc gaaacagtca
     5401 atttcgatca catccgtaat cattacttcc gcagccataa gaccatcaac cctacgggga
     5461 ttatttcaat tggtccatgg caggatctcg atgaaccgca tggacgagat gttcgcttcg
     5521 gttaaaaaaa ggcaccttac gaggtgcctc tgataattag ctaagtgcat gttgttcatg
     5581 tcggatgcgg cgtgaacgcc ttatcaaacc tacaaaacat ttatattcaa tatgttgcaa
     5641 tgaccgcgca ggccagataa gcgtagcgca tctggcgatt ttgcgcttgt catcagtctt
     5701 agcgcgcctt cacagcactt tattaattct ttgaacgaat atttactgcc atttcattca
     5761 cgtctattct taatttgctg ctttaaaaac aagtgattga gcaaaattga ggcaaaaatg
     5821 gactggtatc tgaaagtact aaaaaattat gtcggtttcc ggggtcgtgc gcggcgcaaa
     5881 gagtactgga tgtttattct ggtcaacatc atctttacgt tcgtgctggg gctgctggat
     5941 aaaatgttag gctggcaacg cgctggtggc gaaggcatcc tgacgacaat ctacggtatt
     6001 ctggtgtttt taccgtggtg ggcagttcag ttccgccgcc tgcacgacac cgaccgctcg
     6061 gcgtggtggg cactgttgtt cttaatcccg tttatcggct ggcttattat catcgtcttt
     6121 aactgccagg cgggtacgcc aggcgaaaac cgctttggac cagatccgaa actggaacct
     6181 taaaacaaat ctgctcgccg gatgtctgac tcatccggct tttatcatca tgttgatgaa
     6241 tgaataattt actaatgttt atttaaaata tttcaatgtc gttatataaa ttacctataa
     6301 aaaacaacca tgtatttatc ttaaatatca aaacctttat aacatccgaa aaagaaagat
     6361 acgaatagca tttacacaat acccggaata gactttcgtc acttttaatt aaagggatgt
     6421 ttttatgcag tggtatttag ccgtattaaa aaattatgtt ggtttctctg gtcgcgcacg
     6481 tcgtaaagag tactggatgt ttactctgat taacgccatc gtcggcgcta ttatcaatgt
     6541 cattcaattg attttaggtt tagagtttcc attcctttct ctcatttacc tggcagcaac
     6601 aatcattccg gtcattgctc tgtgtgttcg tcgtctgcac gatactgacc gttcaggtgc
     6661 gtgggcgctt ctctatctgg taccgatcat tggctggtta gttctgtttg tatttgcctg
     6721 tttagaaggc aattctggca gcaatcgtta cggaaacgat cctaagtttg gttcaaatta
     6781 atcttagaat tggggcgaca tttcgcccct ttttattaat aataacaaat attattttcc
     6841 gctaaaaagt ttgggaattt cccgcagaca ccaggatttc gcttccccca tactgtcacg
     6901 acgccaggcc ataataatat cgatctcgct ggtcgattcc gggctgacga cacgcaaccg
     6961 cccttccgca atatcttttt cgaccatcgg atacggcatc gtcgccacgc caagccccgc
     7021 cagtaatgcc tgacgtttat cttcaatcgt gctcaccgtt aagcgcggct gtttgtccag
     7081 cagctgtacg gtcaacaccg ggcgctcacg agcggtatcc gctaccgcaa ttccacgata
     7141 tttcacgcgc gtcacttcag ataacggttc cggctcctga tgaatcgggt gatcaggcgc
     7201 ggcaacgtag acgttcatta aggtatagag cttgcgcgag ttgatctccg acgaggaacg
     7261 aaaatgcata tccggcgcga taacaatatc cgcccgcccc tgctccagtc gttcccacgc
     7321 ccccgccagc acttcggtga tgattgccag ttgggtattg gcttttgccg ccagtttgtc
     7381 gattaacggg aaaaaggcag gtgtcggtac cagcgcctcg gtcacaatgg tgagatgcgt
     7441 ttcccaaccg cgcgcgaggg cttccgcatc ggtagtcagt ttatctgcgg cttccagcaa
     7501 aacgcgccct cgctccagca acatcctccc gacattggtg aatttggtgc gatggcccga
     7561 gcggtcaaac agcaccacat ccagctcttc ttccagtttt tgcatggtgt agctaagtgc
     7621 ggaaggcacg cgtcccagct catccgccgc cgccgcaaaa ctgccccggc gatcgatcgc
     7681 atccataacc cgtagtgctt ccagcgttaa tgccctttct ttggccattt cgttctcatt
     7741 caggaaattt gaacataccg ggcagaatat ctggctaaca atgtagcgtc cagcccctta
     7801 ccataaaagg aagtaaagag aggtcaagaa ttatgattac tacccgaact gccagacagt
     7861 gtggacaagc agactacgga tggttgcagg cccggtatac tttttccttt ggacactact
     7921 tcgacccgaa attgttaggc tatgcctccc tgcgtgtgct taaccaggaa gtgctggccc
     7981 caggtgccgc ctttcagccg cgaacctatc ccaaagtcga tattttaaat gtgattctgg
     8041 atggagaagc agagtatcgc gacagcgaag gcaatcatgt tcaggccagc gccggtgagg
     8101 cgttgctgct ctctacccag ccgggtgtca gctacagcga acacaatctc agcaaagaca
     8161 aaccgttaac acgaatgcag ctttggctgg acgcctgccc gcagcgagag aatccgctga
     8221 ttcaaaaact ggcgcttaat atgggcaagc agcaattaat cgcctcgcca gagggtacga
     8281 tgggaagcct gcaattacgc cagcaagtgt ggctgcacca tatcgtgctc gacaaaggcg
     8341 aaagtgcgaa tttccagttg catgggccac gcgcgtattt gcaatcgatt cacgggaaat
     8401 ttcatgcgct tacgcatcat gaagagaaag cggcgctgac ctgcggtgat ggggcgttta
     8461 ttcgtgacga ggctaacatt acgctggttg ccgattcccc actgcgcgct ttgctgatag
     8521 atttgcctgt ctagttgttt ttacagggag atgatgatga gtaaaaaatc ggccaaaaag
     8581 cgccagccag tgaagcccgt ggtggcgaaa gaacctgctc gcaccgccaa aaattttggc
     8641 tatgaagaga tgttgagcga gctggaagcc atcgtcgcgg atgctgaaac gcgtttagcc
     8701 gaggatgaag ctaccgcgta aagacaggtt gccggatgcg gcgaaaacgc cttatccggc
     8761 ctacaaaatc caacaacatt aacgaattaa acaacccgta ggccggataa gatgcgccag
     8821 catcgcatcc ggcatcaggt acaaaacaca acaacatcaa caagttgagc accccgtagg
     8881 ccggataagg tgcgccagca tcgcatccgg cacaatactc aaaacctggc gtttatctgg
     8941 ccttgctcgc cataatctcg ataatctgcc gatccgtttg ctgcatcgaa tggcttgcta
     9001 acgcacacag gttggcaatc gactgctcaa catcatgcgc cacgatccct tcattgccgg
     9061 tcacggcggt atcatccagc gccattaaca ccgctttcca cgcagccgaa gcactggtcg
     9121 aaaccttcat cgcgcagctg ttcgacgcac catcgcaaat catgccgctg acatcgccga
     9181 tcatactgct gatcgccatc gagatggttt cataacgccc atccaccagc catgccatcc
     9241 cggcggcggc ccccattgct gcggtcgttg cggcacaaag tgcagacaaa cgcggtaact
     9301 ggttatggat gtaaattgcg ctcaaatgag aaagcatcag cgcacgcgcc agccgttcat
     9361 catccgctcc gaagtgttct gctaccacca ccacaggcat tgttgcggtg atcccctggt
     9421 tacccgagcc ggagttactc atagccggaa gcgtagcgcc gcccatacgc gcatcggatg
     9481 ccgcgctggt acgaatcaca atggatgaag agagatcttt cgccagcaaa ccgcgctcgc
     9541 actgtttttc cagcgtcgcg ccaatatgca gcccccactt accgctcaaa ccttcctgcg
     9601 ataacgcaca atttagcttc gcggaatcga gaataaagcg gatcgccgca aacgggactt
     9661 cattgacgaa cttcaggatc tcagccagcg tcgttctgga aagcaccgtc agcggagact
     9721 cttgctcgcc ctctgccaca cacgcctgct gggtaaacac cacaccattg tgcgtctcaa
     9781 tatgcacaat gttggtatgc ccgccgacga tggtgacaca cgcccacttc tcaccgttcc
     9841 agactttggc gcgtgagaag aggatttcat tgcaaggttc ctggatctta acggagactt
     9901 tccccgccgc cagcagtgct ttggcatcgg caattgcctg cgcagttgcg tctttcagca
     9961 cttccagccc ggcgttggca tttccaccta acgcccccag cgccgccgca atcggcagcc
    10021 ccaccattcc cgtgccggga acggtgacgc ccagaccgtt cttcatcaga tttggcgaaa
    10081 cccaggcttc tacacgttca accggacctt ccagttctgc cgcagcaacc gccgccgcca
    10141 gcgccagtga aatcggttca gtacatccca gcgccggttt tacttcctcc tgaacggcga
    10201 ggatgtaacg ctgccataac ggatttaaag tcgaatcaaa catattaaaa accttaaaat
    10261 ttcaggtaaa tcaagaaaat gccaggaacg gagaaacaca aagcaacaaa ccagtgacga
    10321 taatcaggta cagagacatc cctttgtatt tgtgcaatgc cggtactttg taaaccagcc
    10381 acgccgggat caggcaccct accatgccga aaatcgggct acagatagag gtgaagctca
    10441 acaccggtgc gttcagtacg atggcgctcc aggccagcaa aatggcgaaa atcatgatgc
    10501 cgcgctgaac aagattttcg ttaatcttct cggcaggcat cttgcgacgc aggatgttca
    10561 ttacgatccc ttgcgttgct tcgcgaaagc ctaaatagac gccaaagaat gcagtcatga
    10621 cagcaaagat attgagaatg acgctgacca ctttcaccca cgctgcgccg tcaccgctaa
    10681 taaactgtgc ggcaatcgcc agcgcggaaa tattctgctc ataggctttt accgcttcgt
    10741 catgtcccat cgccagcgtg aacgacacgg cgtagaaaaa gacggtgaca aacaaaatgc
    10801 caaacgcgat attcattgcc cgcaatgctt tatgccgcgc cacttcaatt gatttttccc
    10861 gcgagcgata agagatcacc atcgggctta acgtctggat aaacagaatc gacgtcaggg
    10921 taaacggcag cgtaataatg gcgtttttca ccagcagccc cagcggcggt agcgaaccga
    10981 cgttatacag atgccacatt cccaccatcg acacgcccag cgccgcgacc accagcagct
    11041 tggtcagcac catgccggtc gaaattttga ataacaattt ctcgccgcgt gaagagatcg
    11101 ccaccagaat gcaaatcagt accagaccat aaaagggact gtctgacagc aacccttccg
    11161 tcacgccgaa ggtatgcaga taggaagcac tatcgttggt gatggcggtg gaatagacga
    11221 acatccaaat caccagcatt acgaaataga gcgcacctaa caggatgccc cagtttttac
    11281 ctaaataacc gctaatgaca ctcgggtaat ctttacattc tggtgattct gccagcgtat
    11341 taataaacaa ccgctgaaac agatacattg ccgggtaacc aatcaccgat gagagcaaaa
    11401 atacccacaa tcccatcaaa ccgacctgca ccgggagaaa aacaatcccc gcgccaatcg
    11461 ccatcccgat actcataatc acccagccgg tgtcagtact gtcgaatttg atcgcttctc
    11521 gccactcgct ctcactcatt ccagcacgac ccgccggggt cgaagcgtct gcaatgacgc
    11581 ctttattcga tgcaatttcc ataatttctc gctcaatatt ttgtagggct tattattttt
    11641 ttccgagccg catcaaggcg atatgcggtc tacgtttttg caggcgagtt attagaataa
    11701 agaaatgata cgcgcgaggt cagagaaaat cttcacaatc aagactttga aataacggag
    11761 atggataaga attttctact aaattaatcg caagagaata ttcattctct atttgcggca
    11821 gatcacaaaa aaaaggtgca catttgtgca cccaaggatg aaagctgaca gcaatgtcag
    11881 ccgcagacca ctttaatggc cagtcctccg cgtgatgttt cgcggtattt atcgttcata
    11941 tctttgccgg tttcatacat cgtctcgatc actttatcga gtgaaacacg cggtgccgag
    12001 gtgcggcgca tcgccatccg cgcggcgttt actgctttca cggcattaat ggcattacgt
    12061 tcaatgcacg ggatttgtac ctgtccggca accggatcgc aggtcagccc aaggttatgc
    12121 tccatcgcga tttccgccgc attgcatacc tgcgccggac tgccgcccag tagttcagtt
    12181 aaccctgccg ccgccattga acaggccacg ccaatctccc cctgacagcc gacctccgcg
    12241 ccagagatgg aggcgttcat tttatacagc gcgccaatag cccccgctgc cagaaaatag
    12301 cgggcaattg accgctcgtt taccggacga cggaacttat cgtaataagc cagcactgcc
    12361 ggaataatgc cgcacgcacc gttagtcggt gccgttacca cgcgcccgcc agctgcgttt
    12421 tcttcactaa ccgccagcgc gtacatgttg atccagtcga tgacattcat cggatcgtta
    12481 gagatgttat cgctggaaac cagctgacga cgcagcgcta cggcacgacg cggcacattg
    12541 agcggaccag gcagcacgcc ttcagtgttc atcccgcgtt caataccgtc atgcatcact
    12601 tgccagatac gggcaaaccc tgcgtcaatt tccgctttgc tgcgcagcgc cagctcgttg
    12661 tgcatcatca ggccagatat agacaggccg ttgtaatcac acattttcag cagttcacct
    12721 gctgagtgga aatcgtaagg tacggacgtt tcgacatcgt gcgacaggcc gaagtgttct
    12781 tcttcgacaa taaacccgcc gccgacagag taataggttt tacttaatag cgcttcctgt
    12841 cccttccagg cagtgatccg cattccgttc tcatggcgag gcaacatttc gggatggaag
    12901 ataatgttct ttgctacagg aaaatcaaca atatgcgcac cagatgccac tggcagccgc
    12961 ccgctgcgcg ttactaactc tataaatgca gggatctcat caatgacaac atcctgcgga
    13021 ctgtttcctg ccagtcccat gataatggcg acatccgtgg catggccttt gcccgtcagt
    13081 gacaacgacc catacagatc gaccacaata tggctcgtcg cggttaataa gccgctactt
    13141 tccagccgat caataaaact ttttccggca ttcattggcc ccacggtatg cgaactggag
    13201 ggaccaatcc caattttgaa aatatcgaat gcactaatca tatccacacc ctcggattgc
    13261 cgttcagtga agtggagcgg aacgaccttg cgaccgtccc gctcacgagg ctttacgcac
    13321 tacgtactgc gatagcttca atttccagct tcacatcttt cggcaaacgc gcaacctgca
    13381 cacagctccg ggtcgggtag gtcgcctgat gctcatcgaa gaactgctta tagacttcat
    13441 tgatggtggc aaaatcattc agatcggtga tgaacacggt catcttgatg atatcgccca
    13501 cgctcagccc ggcagcaacc acgatcgctt tgacgttttc gaggcttaaa cgcgcctgat
    13561 cttgcacatc agccgggatc tcaccggtct gcgggcaaac cggaatttgc ccggaggtga
    13621 agaccatgct gcctaaatca acgccctgaa cataagggcc gattgcgcct ggggcacgtt
    13681 gcgtttcgat aatctttttc atacatcctc cggcgtcaga gcgcctgggt aaaagtacgt
    13741 gaaataacat cctgttgctg ttcacgggtc agtgcgttga agcgcacggc gtagccagag
    13801 acacggattg tcaggttagg atatttttcc gggtgctcga tggcatccag cagcatttcc
    13861 cgattcatta cgttgacgtt gaggtgttga ccgccttcga catccgcttc gtggtggaaa
    13921 tacccatcca gcaggccgac aaggttggtt ttacgtactg gatcttcttt gcccagcgcc
    13981 gcaggaacga ttgagaaggt gtacgagatc ccatctttgg cgtaggtgaa cggcagtttc
    14041 gccaccgacg tcaatgaggc cacggcacct ttgcggtcac gaccatgcat cgggttagcg
    14101 cccggcgcga acggtgttcc ggcgcgacga ccgtccggcg tattaccggt tttctggccg
    14161 tacaccacgt tagaagtgat agtcagaatc gactgggtag ggacggcgtt gcgataggtt
    14221 ggcagcgctt taattttctt cataaagcgt tcaaccaggt cgcaggcaat gctgtctacg
    14281 cgctcgtcgt tgttgccgta ctgcggatat tcaccgtcga tttcaaagtc caccgccagg
    14341 ccgttttcgt cacggattgg tttcacgcgg gcatatttga tggcagacag ggagtccgtc
    14401 gccaccgaca ggcccgcgat gccgcatgcc atagtgcgat agacatcacg atcgtgcagc
    14461 gccatcagcg aagcttcgta gctgtacttg tcgtgcatgt agtgaatgat attcagcgcg
    14521 ctgatgtact gcaccgccag ccagtccatg aagtgatcga ggctgtccat cactttgtcg
    14581 taatccagca cgtcgtccat cagcggtgct gttttcggcc cgacctgaat cttcagcttc
    14641 tcgtccaccc cgccgttaat tgcgtagagc agcgttttcg ccaggttagc gcgtgcacca
    14701 aagaactgca tttgcttacc aatcaccatt gggctgacgc agcaggcaat cgcgtaatcg
    14761 tcgctgttga agtcagtacg catcagatcg tcattttcat actgcaagga agaggtgacg
    14821 atcgacacct gcgcggcata ttttttgaag gcaatcggta attcttccga ccaaagaatg
    14881 gtcaggttag gttccggtgc cggccccata gtgtgcaggg tgtgcaaata gcggaaggag
    14941 tttttggtca ccagcgtacg accgtccagc cccatcccgc cgatcacttc cgtcgcccag
    15001 attgggtcgc cggagaacag cgaatcaaat tccggtgtac gcaggaagcg taccatacgg
    15061 atcttcatga tgaagtgatc gatcagttcc tgtgcctgct gctcattgag tacgccagct
    15121 ttaaagtcgc gctcaatgta gatatcgagg aacgatgccg tgcggcccag cgacatcgcg
    15181 ccgccatttt gcgatttcac tgccgccaga taagcgaagt agagccactg caccgcttcc
    15241 tgcgcattct gcgccgggcg agagatatca aagccatatt tcgccgccat ttcctgaatc
    15301 tgcaacagcg catgacgatg ctctgccagc tcctcacgca gacggatggt ggcttccaga
    15361 tcctcgcctt tttccagacg agactggaga tcggcaaatt gcagttcgcg ttcacgtacc
    15421 agataactga tgccatacag cgctacgcgg cgatagtcac cgataatgcg cccacggcca
    15481 tagccatctg gtaaaccggt cagcacgcca gatttacggc agcgcagcat atccggtgag
    15541 taaacatcaa atacgccctg gttatgggtt ttacgcagat cggtaaacag atattcaaat
    15601 tcactgtcca tttcacggcc ataggcatgg aatgaacttt taatcatatt aatgccaccg
    15661 aacgggtgta gcgcacgttt caacggcgca tccgtttgca ggccaacaat tttttccagc
    15721 ggctggttaa tatatcccgc atcatgagcg gtaattgtgg tggcaatatt ggtatcgaaa
    15781 tcaaccggcg cgtgggttgc attttcgata cggatgcctt ccattacttt ttcccacaat
    15841 tccgtggtgg caggcgtcgc ttcggcgagg aaagattcat cgccttcata cggtgtatag
    15901 ttatgttgaa taaaatcgcg gacattaatt tcgtttttcc agtccgtacc tttaaagcca
    15961 agccatgcgt cggcgtacag cttatcgctg gtatcaatat ctaccttcat gaaaaataat
    16021 ctctctacaa tacttcaact aaattatgca aattctgcgg gcgcgttaac tttgcctaaa
    16081 tgaatggcat ccaaagcaat cattttttct tcgttagtcg gaataacggc acaaatgaca
    16141 cgcgcatttt cactggaaac aattcgctca ccacaggagt tagagcgatt attcatttct
    16201 gtatcaatct ctacgcctaa tacagccaaa tgttccatga ccagacgacg aattaagctt
    16261 gaattctctc ctattccgcc ggtgaatata attccatcca ggcgacgtaa tgaagctgcg
    16321 tgtccggcaa tatgacgggc aattcggtga acaaaggttt taattgccag ttgcgcgcgt
    16381 tcgtgacctt catgccaggc tttttccaga acacgtaaat ccgaagaaag accggaaata
    16441 cctaataatc ccgactcttt attcactacg cgttccaggt cacccaggct ctggttggtt
    16501 tggctggcga cccaggacat cgcaccaaag tcgacatcgc cactgcgggt acccatcatc
    16561 aagccttcca gcggcgtcat tcccattgaa gtatcaacac tctgaccgtt gcgaaccgcg
    16621 cagattgacg cgccattgcc aagatgcgcc acaaccaggc cggagtcatc ttccgccaga
    16681 ttcagcagcg aatgtgcgcg ctgggaaaca tagcggtgcg acgtgccgtg gaaaccataa
    16741 cggcgtacac ctaactcttc ataatatttc cacggcaggc cgtataaata agcttccgga
    16801 gccatcgtct ggtggaaact ggtatcaaat accgccacct gagttacgcc cggaaataat
    16861 tgctgcgccg attcaatacc acttaaattg gcgtaattat gcaggggtgc cagtggagaa
    16921 acgcgacgga tattatcaat gacttcatcg gtaataatgg cggactcggt aaaaatactg
    16981 ccgccgtgag cgatgcggtg gccaattaag gccacactgt catttaaatt ccgtttttcc
    17041 agttcaaatg caattgcctt caatgcacct tcgtagctgt ggtgagccag cggtgctggc
    17101 tctcccccat ttacggataa gaatgcattt tccgagttaa taccgtcggc aatacctgac
    17161 attaatactt cacagtcgct ggcatcgagt acggaaaact taatcgaaga cgaaccacag
    17221 ttaataacca aaacaaccgg aaattcattc atctcttttc tcatcctgag ttacggatta
    17281 aaacagtttg tatacgatgt tcaggatggt cagcagacca atcacggtaa caaacacgtt
    17341 atccagacga ccacggtatt tcgccagaga cggcgcttta cggatggcat acatcggcaa
    17401 caggcacagc agggatgcga taatcggtgc gcccatggct tcaataaggt cgaggatgtt
    17461 cgggttggcg taggcaacaa cccaggtgga gcccatgatg aagatcatgc tgatagtgtt
    17521 cagtttaccc agcgacactt tagttttgtc gcctttataa ccgaacttca gaatcagacc
    17581 attcaagcct tccagcgtcc ccagatagtg accgaagaaa gatttgaaga tagccacgag
    17641 tgcgatgatg gaagccgcat attccagtgt aatcgcgaac gttgttttgg taccggtcat
    17701 ggacgcaaag tggttagcca gataagaaag cactggaata ttctgcgctt tggcttccgc
    17761 catgttggcc ggagacagcg taaacaggca gctaaaggca aagaacatca ccactgcaac
    17821 catcagcatg ctggcacgag aaatgatttg ggaacattta cgttcggtga agtcgcgacc
    17881 gaagtctttc tcatactctt cacgtttaga aaccacgaag gaagagacga ttggcgagaa
    17941 gttaaaggag aaaaccatga tggaaatccc cagccagaca gtgatcagga taccgtcatg
    18001 accggttaac gacagcgaac cgaggtcaac ctggtcgata actgcagagt tccagtaagg
    18061 gatcagcgac agagaaatca gcaccaggct ggcgataaac ggccatacca ggtagctcat
    18121 cactttaacc atcagatcct taccaaacca gatgacgaaa gccatcagca gcaacaggaa
    18181 cagcgccaca aagccgcgat tcagcggtgc aaatccgagc tggttttccc agaacgtcat
    18241 aaaggtattg gtaatagtaa cgccataaat ccacagcagt gggcaaatcg cgaagaagta
    18301 caggaacgtg ataaccacgc cgccagtttt accaaaatgc tcttccaccg tttccgtaat
    18361 gttgccggaa gggttagagc cagaaagaca cagacgcgcc agcgcccggt ggcaataaaa
    18421 tgcgatgggg tatgccaata ccaacatcag aagaatcggg atcagtccgc caaaacctgc
    18481 gcggataggg aagaacagca ccccggcgcc gattgccgta ccaaacaagc ctaacgtcca
    18541 tgtggtatct gatttacgcc aggacgattg ttttgtctgg ctggatacaa tgctatctga
    18601 agtactcata tcctatcctc aacgaattaa ttaagcgtca acgaaaccgg tgatttgaga
    18661 gacgcgagaa agatcgatat tgccgccgga aataatactg acggtttttc tgttttgaat
    18721 atattggtct aatttaccgc ttaataatgc agcacatgcc agagcgcctg cgccttcggt
    18781 gacgacttta ttgcgctgaa ttaaggcaat catactgttt ctgatttcgt cttcgctgac
    18841 cagcacgatg tcatcgacta attcacgaac gatttcgtaa gttaaattac ccgggcggga
    18901 gacatcacaa ccatccgcca gggtgccggt agttcggtgc gtggttattt ctccggagtg
    18961 gaaagaagcc gccatgccgt gaacgttttc tgactgtacg ccaataacac gaatggtcgg
    19021 gttaatagat ttaattgcca ccgcaatacc agcaattaaa ccaccaccac caattggcac
    19081 aatcacgtta tcgacatcat agagatcttc cataatttcc agaccaatcg ttccctggcc
    19141 agcaatcact ttcggatcat cgtaaggtgg gataaaaata cgaccttcca tttcgacaat
    19201 ttcgctcact ttagcgatag tgtcgttgaa attatcacca tgcagaacga cttctgcgga
    19261 gtagtcgcac gttgccgcta ctttggattt tggcgcacct tttggcatca ccactttacc
    19321 gtcgataccc agcatcgcgc aggagagcga aaccccttgc gcatggttgc ccgcagaaca
    19381 ggccactaca cctttacgtt tttccgcatc aatcagtgaa cttaatttat taaatgcgcc
    19441 acgaatttta aatgaacccg tacgctgcat attttcaaac ttcaggaata tttcaccttt
    19501 gcaacgttca ctaaaatagt ttgagcgagg catgcctgtt ttataaattc gcccagccag
    19561 tcgttgtttc gcttcaataa tgtcatcaat agcaaccggc agatcgtatg taatatgcat
    19621 tataaaacct cttcgcctga attaaatatg taggtaaccg taaccgacac ctgcaaaaca
    19681 gacaggtgga ttatttatgt ttaaataaaa acaaataact aaccaacttc tattaattgc
    19741 cttcgtctac acccattata agatgaatac tctttggcta attccaccaa aaccgatgct
    19801 gcttttttaa tacgataatt tttcgaccat accgcggcat attgtgccac aggtaatgtt
    19861 tcttcaaccg gaatagtaat aaattgattt gaaccaaaag gtgacgtcat atcacaagga
    19921 attacagtta agaaatcagc attgagaaca agattataaa ttgtcacgac tgagtcggtt
    19981 ttaacgatgt tttcaatact gatgccattt ctttgtaacg tagtaagaag ctcgctgtag
    20041 taccccatat tggtttgtgg caacacccac tgttcgttct tcaacgactc cagcgtggtg
    20101 gtgccggtgc atgttcggga cttactggct accaacacaa actcggactc gaacagcggc
    20161 tcaacatgta aatcctgaag cttcatttct gcacttaacg taccaatcgc aaaatccagt
    20221 cgaccgtcgc ggattgccgg taagaacgaa gacagttgcg cttcatacat agaaacttgc
    20281 gctttcggga acacctcttt gaacttgttg atcatccctg acataaaagt aaaaccaatc
    20341 aatgaaggaa aaccaaatga gacttccacc accgcctcag aagacatacc acttatctca
    20401 ttaaccatat ttttcatttc acgggtaatg gattcggaac gggagagtaa caattgaccg
    20461 gcaggtgtta atgttacacc ggtatttttc cgcaccacta attccacacc aaaataatct
    20521 tcaatatcgt taatgatttt actgacggct ggttgagtta accctaattc ttttgcagcc
    20581 gagccgatag agccacttct aatgacttcc tgaaagacta ccaggtgctg cgttttcgga
    20641 agaagaatag tgctcataac gacctacgtt aattacctca ttgacggcat gaagtgtatc
    20701 aaaatgaaat gaacaggata tgtgcgacca ctcacaaatt aactttcaat actttccagg
    20761 gtatcgttat tacaattaaa cacctttaaa tatcaacaag ttaaagcata aaaatcagca
    20821 taaaccctga tttttgtcaa aaaaaatgac ggggataacc atattttatg gcgataacat
    20881 cattcgttat gtggttaata caaaaaaggg gctgagacca tatttcaagc aattaccgga
    20941 taattaccag gcaaaatttg agttaaattt aatgagcaag ttctcaaatt ttattataaa
    21001 taaaccattt tcagcgataa atactgcggc acgtcacatt ttttcacgct atttgttgga
    21061 gaacaaacat ttattttatc aatattttaa aatttcgaat acaggtattg atcatctcga
    21121 acaattgatt aacgtcaact ttttctcttc tgacaggacg tcattttgtg aatgcaatcg
    21181 ttttccataa attcttctcc cctcataggc gacgaatagc attttgtgtt gaggatcaca
    21241 aaacgaataa ttgctgatcg ccgcgataag gtcagacaaa gacaacaagg gaaattttca
    21301 cagagctttt gatcgtcgta ggccacagaa tgttgcttcg tttactgtaa cgccgggtaa
    21361 atgagcgttt tttgatagtg cgaaagaacc ctgcgaggaa aataagcatc tattattgtt
    21421 tgtcatgacg acaaggcagg catcaatgaa aggcttccca attgcacata tttttcaccc
    21481 ttcaatcccg ccaatgcacg cagtggttaa caatcacaat agaaatattg attattggac
    21541 ggtaaaaaga aagtttgcag aaattgtctc caccaatgac gttaataaaa tttacagtat
    21601 aagtaatgaa ctgcggagag tattatctgc aattactgca ttgaatttct atcaaggcga
    21661 tgttccttct gtcatgatcc gaatccaacc ggaaaatatg agtccattca tcatagatat
    21721 ttctacagga gaacatgacg attatatcat acaaacatta gatgtaggca cttttgcacc
    21781 ttttggtgaa caatgtactt gctcagccgt caataaaaaa gagctggaat gtattaagga
    21841 gacgatttct aagtattgtg caaaattcac ccgaaaagaa gccatcttaa cacctcctgc
    21901 gcactttaat aaaaccagca ttacttcaga ttg
//
LOCUS       DAZUDJ010000076        21327 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.076, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000076 DAZUDJ010000000
VERSION     DAZUDJ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21327
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.076"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            289..789
                     /gene="tssB"
                     /locus_tag="ACHY1N_003972"
     CDS             289..789
                     /gene="tssB"
                     /locus_tag="ACHY1N_003972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HFS4046184.1"
                     /translation="MSKKFEGSVAPRERINISYVPKTDGQTAEVELPLNMLVVGDTGN
                     TQETSPLDERQAVSVNKHNFGAVMAEAAIGLNFTVPATLKGSTTDDELNVALNIKSLD
                     DFSPDSVARQVPEVNKLLELREALTALKGPMGNLPAFRTQLQALLENEESREQLLKEI
                     GLVSNK"
     gene            824..1048
                     /locus_tag="ACHY1N_003973"
     CDS             824..1048
                     /locus_tag="ACHY1N_003973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046185.1"
                     /translation="MTAHKNISETYHLSVADILQVVYQVCFSPSVEINQDGVAALITT
                     LDRRISDLLDEIIHFCEFQQSASHWQRVLH"
     gene            1099..2574
                     /gene="tssC"
                     /locus_tag="ACHY1N_003974"
     CDS             1099..2574
                     /gene="tssC"
                     /locus_tag="ACHY1N_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001501045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HFS4046186.1"
                     /translation="MSLQEEELVSSHAGQPEQASSLLDQIMAQTRIQPGSEGYDVARQ
                     GVTAFIASILQSTASAEPVNKLAVDSMIADIDERISRQMDVIIHAPAFQQVESFWRSL
                     KTMVDRVDFRENIKVNVLHVTKQELLEDFEFAPEIIQSGFYKHVYSSGFGQFGGEPIA
                     AVLGAYEFKNTAPDMKLLQYVSAVGAMAHAPFLSSVSPEFMGLNSWTELPNIKDLYAI
                     FEGPAYTKWRALRDSEDSRYLGLTAPRFLLRQPWSPADNPVKSFNYHEDVSQNHEDYL
                     WGNTAWMLACNIADSFAKYRWCPNIIGPQSGGAVKDLPVHLFETMGQIQAKIPTEVLV
                     TDRREFELAEEGFITLTMRKDSDNAAFFSANSVQKPKHFPGKDAETNYKLGTQLPYLF
                     IINRLAHYIKVLQREQLGSWKERSDLERELNTWIRQYVADQENPPADVRSRKPLRAAR
                     VEVMDVEGEPGWYQVALSVRPHFKFMGANFELSLVGRLDRE"
     gene            2581..2994
                     /gene="tssE"
                     /locus_tag="ACHY1N_003975"
     CDS             2581..2994
                     /gene="tssE"
                     /locus_tag="ACHY1N_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HFS4046187.1"
                     /translation="MIPDRERTTGSLFERMEASSARNRQGGSIHSLRQSIRQNLRNIL
                     NTRSGSCRGAPELGIDEPEGAENFRESMSRAIEQCIERYEPRISHAEVQAVVSSASSP
                     LDMTFHITAWVTFNETHEVLEFDMAPNGSQHYRVD"
     gene            2998..4848
                     /gene="tssF"
                     /locus_tag="ACHY1N_003976"
     CDS             2998..4848
                     /gene="tssF"
                     /locus_tag="ACHY1N_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HFS4046188.1"
                     /translation="MEFEERYFREELDYLRQLSKLLATEKPHLARFLAEKDADPDIER
                     LLEGVAFLTGNLRQKIEDEFPELTHGLIKMLWPNYLRPVPAMTLIEYTPDMDKSSVPV
                     LIPRNEQFTTNAGEIRVDEVLPSDAKKEEPPPCTFTLCRDIWLLPVRLEQIENRSTTR
                     NGVINITFSVAPGTDFRTLDLNKLRFWLGNDDNYTRDQLYLWFCEYLQGADLTVGEQH
                     IRLPEFMLKAVGFEPQDAMLPWPKNVHSGYRILQEYFCYPDAFLFFDLCGCPALPDGL
                     QAEFFTLQLRFSRPLPVDIRLRRDSLRLYCAPAINLFIHHAEAITLDNRRADYPLVPS
                     RHYPQHYDVFSVNSVVSQVQDMFRKKDLGRPVSTQAARQWPAFESFSHQMEYSRKREV
                     VYWHHRTKTSLFHRGFDHTLAFIHADGSYPSDESLLSNEVVSVSLTCTNRELPSQIRS
                     GDITGTTGKNAAVASFRNITRPTQPLWPVIDGSLHWSLLSAMNLNYLSLLDTDALKQV
                     IANFDRHAIHHPQTARLSQQKLDAIERLETRPVDRLFTGIPVRGLASTLYLHPEPFVC
                     EGEMYLLGTVLSHFLSLYASVNSFHMLTVVNTESQETWKWTERIGQHPLI"
     gene            4812..5894
                     /gene="tssG"
                     /locus_tag="ACHY1N_003977"
     CDS             4812..5894
                     /gene="tssG"
                     /locus_tag="ACHY1N_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HFS4046189.1"
                     /translation="MDGKNRAASSYLSPGNPPADKEQNDPLAQVFHNACSYNFFAMAE
                     LLHRLAKGEKGTPELSLRDDPAQETLRFSADASLAFPCSDISALKRDTSGAFRMTTTF
                     MGLQGSQSPLPGYYLDHLAWKAVHEQSPVGDFLDMFSHRLTQFVWHIWRKYRYHISFR
                     NGGVDAFSQRMYSLVGLGHRQLRDKLAINHSKMLAYSGILANPGRSPEIICGLVSHCF
                     DLSEVTLQNWQRRKVDIEPDQQNSLGSYSLKNGEKLAGRSVLGNFVLGTRVPELSGKF
                     QLSITSLTRKQFLSFLPSGENFLPLTMFVSFILRDQLAWDLHLGLAPEQVGAMRLGDN
                     KSALLGWTSFLGTPEERPSVTIRVRS"
     gene            5919..7199
                     /gene="tagH"
                     /locus_tag="ACHY1N_003978"
     CDS             5919..7199
                     /gene="tagH"
                     /locus_tag="ACHY1N_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated FHA domain
                     protein TagH"
                     /protein_id="HFS4046190.1"
                     /translation="MPEEKLQTLSLQVINGSELESGRAARCLFTQQGNVGHGPECHWS
                     VQDRQQSIPAQAFTVILHDGTFCLRPQTAQLWLNQAKVTATSDLIQLRQGDEIQIGRL
                     MVRVHLNRGDIPHYDEEMATPETIVTNRDMLTDTLLSTEGTPHYPGMTHRHQLADTVV
                     NGFSADPLQALQSESLITTGDPLSGIAAVRPSAPLSDPASNGGINTPFMDLPPIYASP
                     GDRNDDVSAAEMAQRHLAVTPLLRGLGGSLTMSNSDDADDFLEEAGRTLQAAIKGLLD
                     LQQQRNSLSDKHLRPLEDNPLRLNMDYATALDVMFAEGKSPVHLAAPAAVSESLRNVR
                     HHEEANRAAIVESLRVLLDAFSPQNLLRRFVQYRRSHELRQPLDDAGAWQMYSHYYEE
                     LASDRQQGFEMLFNEVYAQVYDRVLREKQREPEA"
     gene            7196..7720
                     /gene="tssJ"
                     /locus_tag="ACHY1N_003979"
     CDS             7196..7720
                     /gene="tssJ"
                     /locus_tag="ACHY1N_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HFS4046191.1"
                     /translation="MNRKAFLACVLMCVILTGCETAKKISEVIKNPDIQVGSLKEQPS
                     EITVTLLTEPDTNTNAEGESAAVDVQLVYLTDDSKLLAADYDQIASTPLPDVLGKNYI
                     DHQDFNLLPDTIKTLPPVKLDEKTQFIGVVAYFSDDQATEWKQIETVEGTGHHYRLLV
                     HVRQSSIEMKKEDE"
     gene            7723..9054
                     /gene="tssK"
                     /locus_tag="ACHY1N_003980"
     CDS             7723..9054
                     /gene="tssK"
                     /locus_tag="ACHY1N_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HFS4046192.1"
                     /translation="MATTRNKVMWQEGMLMRPHHFQQQQRYNDYLDNQRFRAMNDLSW
                     GFTELTLNNELLAQGKIMIDSASGTLPDGTVFSIPDQDALPDPLHPQNFPDERSRNIY
                     LALPVASDVRNEISDGRRIGRYRLNYADVRDLHSEEGDARTLTLGQLTPRIMSGAEDM
                     SAYITLPLCRISDRHADGSLTLDDDFIPSCQNIQVSKKLRVYLKEVQGAIGGRASDLA
                     NRIGSPAQSGIADVAEFMMLQLLNRNQTRFTHRARRSQLHPEDFYLDLAGLLGELMTF
                     TEPSRLPCPLDVYDHHDLTKTFKTLLPEVKRALHTVLSPRAVNLPLHLRDGIWQADIH
                     DTELLQSATFVLAVAANVPVDQIQRQFIQQSKISSPEKIRNMVSVQIPGIPLRALMVA
                     PRQLPYHSGFSYFELDKSGQAWTEMAAAGAVALHVSGSFPDLNMQLWAIRG"
     gene            9059..9820
                     /gene="icmH"
                     /locus_tag="ACHY1N_003981"
     CDS             9059..9820
                     /gene="icmH"
                     /locus_tag="ACHY1N_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IVB secretion system protein IcmH/DotU"
                     /protein_id="HFS4046193.1"
                     /translation="MDEGSLSLPPFTGYDEKSQRNYHLALRGNSLNPMIDAATPLLGM
                     VMRLSTMNSQTMPEHLFAQVVTDVQAVEQLLQEQGYEPGVIISFRYIPCTFIDEAALG
                     NGWSNKNEWIKQSLLVHFHNEAWGGEKVFILLERLIREPKRYQDLLEFLWICFSLGFR
                     GRYKVAAQDQGEFEQIYRRLYHVLHKLRGDAPFPLLHQDKKTQGGRYQLISRLTVKHI
                     FCGGVVVLALFYLFYLLRLDSQTQDILHQLNKLLR"
     gene            9829..12584
                     /gene="tssH"
                     /locus_tag="ACHY1N_003982"
                     /gene_synonym="clpV"
                     /pseudo
     CDS             9829..12584
                     /gene="tssH"
                     /locus_tag="ACHY1N_003982"
                     /gene_synonym="clpV"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308250.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
     gene            12581..13324
                     /gene="vasI"
                     /locus_tag="ACHY1N_003983"
     CDS             12581..13324
                     /gene="vasI"
                     /locus_tag="ACHY1N_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated protein
                     VasI"
                     /protein_id="HFS4046194.1"
                     /translation="MSRLRVFRQTGWFIAGLMTGLPATAAPAEASSMAGVAVAVATTT
                     PPDATATLQAMQSCRRESAALERLDCYDRLLAPLSPSGFDGALVKAGFVGEAWTRATE
                     QEKHRQGNTTELLVTQVPGERPTVVITTPAIGHVPPRPVLMFSCVDNITRMQVALMHP
                     LDVHDIAVTLNADNRALRSHWFVRENGTLLESSRGLSGIDEIKQLFGAKTLTVDTGAD
                     NAAGKLTFNIDGLARAIAPLRDACHWAGE"
     gene            13329..14741
                     /gene="tssA"
                     /locus_tag="ACHY1N_003984"
     CDS             13329..14741
                     /gene="tssA"
                     /locus_tag="ACHY1N_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssA"
                     /protein_id="HFS4046195.1"
                     /translation="MAMDLRDPNVWISHLLENLPEEKLASALKDDNPNWEYIDGEIVK
                     LGSLAHSQLDIPELQRRGLVILASESKDFRLLAHLLRTLQHAGDPHLALRLLALYVEH
                     YWAVAAPQNMAHKKRFASQVIKRFETGIEVFSQNAATAQRDALSGELAKLAQCWQSHN
                     APELAQATDDLFALYQRAFNRAAPAPVPTPAASGSSPQTTATSESGVTQPSAPAPQIV
                     IDSHDDKAWRDTLLKVAAILCERQPDSPQGYRLRRHALWQNITSTPQAESDGRTPLAA
                     VSADMVADYHAQLGSADMALWQQVEKSVLLAPYWLDGHCLSAQTALRLGYKQVADAIR
                     DEVIRFLERLPQLTGLLFNDHTPFISEQTKQWLAASPDAKVAPVAQIGEESKAARACF
                     AEQGLEAALRYLDMLPEGDPRDQFHRQYLAAQLTEEAGLVQLAQQQYRMLFRMGLQMM
                     VADWEPSLLEQLEQKFTAEQ"
     gene            14850..18284
                     /gene="tssM"
                     /locus_tag="ACHY1N_003985"
     CDS             14850..18284
                     /gene="tssM"
                     /locus_tag="ACHY1N_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system membrane subunit TssM"
                     /protein_id="HFS4046196.1"
                     /translation="MLILAWIFLLVWIWWKGPTWTLYEEQWLKPLANRWLATAAWGII
                     ALMWLTVRVMKRLQQLEKQQKQQREEAIDPLSVELNAQQRYLDRWLLRLQRHLDNRRF
                     LWQLPWYMVIGPAGSGKTTLLREGFPSDIIYAPEGSRGAEQRLYLTPHVGKQAVIFDI
                     DGTLCAPADADILHRRLWEHTLGWLKEKRARQPLNGIILTLDLPDLLTADKRRREYLL
                     QTLRSRLQDIRQHLHCQLPVYVVLTRLDLLQGFAALFQSLNRQDRDAILGVTFTRRAH
                     ENDDWRTELNAFWQTWVDRMNLALPDLMVAQTHTRASLFSFSRQMQGSREPLVSLLEG
                     LLDGENMNVMLRGVYLTSSLQRGQMDDIFTQSAARQYRLGNNPLASWPLVDTAPYFTR
                     SLFPQALLAEPNLATESRDWLMRSRRRLTVFSATGGVAALLLITGWHHYYNGNYQSGI
                     TVLKQAKAFMDVPPPQGKDDYGNLQLPLLNPVRDATLAYGDWGDRSRLADMGLYQGRR
                     IGPYVEQTYLQLLEQRYLPSLFNGLVKAMNAAPPESEEKLAVLRVMRMLEDKSGRNNE
                     VVKQYMAKRWSEKFHGQRDIQAQLMSHLDYALAHTDWHAERQAGDGDAISRWMPYDKP
                     VVSAQKELSKLPVYQRVYQSLKTRALGVLPADLNLRDQVGPTFDQVFTSADDNKLVVP
                     QFLTRYGLQSYFVKQRDELVELTAMDSWVLNLTRSVKYSDADRAEIQRQLTEQYISDY
                     TATWRAGMDNLNIRNFESIGQLTGALEQVISGDQPLQRALTVLRDNTQPGVFSEKLSA
                     KERDEALAEPDYQLLTRLGHEFAPENSTLAVQKDKESTMQAVYQQLTELHRYLLAIQN
                     APVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGRLADQAWHVVMVEAV
                     HYMEVDWRDSVVKPFNEQLANNYPFNPRSAQDASLDAFERFFKPDGILDTFYQQNLKL
                     FIDNDLSLEDGDNSVIIREDIIAQLKTAQKIRDIFFSKQNGLGTSFAVETVSLSGNKR
                     RSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGTSGNAPRSISFSGPWAQ
                     FRLFGAGQLTGVQDGNFTVRFSVDAGAMTYRVHTDTEDNPFSGGLFSQFGLSDTLY"
     gene            18295..19744
                     /locus_tag="ACHY1N_003986"
                     /pseudo
     CDS             18295..19744
                     /locus_tag="ACHY1N_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VasL domain-containing protein"
     gene            19671..20153
                     /locus_tag="ACHY1N_003987"
     CDS             19671..20153
                     /locus_tag="ACHY1N_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HFS4046197.1"
                     /translation="MANISYLSLSGETQGLISAGCSTLDSVGNKAQPEHKDQIMVYAL
                     MHSISRSQNVNHHELIITKPVDKSSPLLAKALSDNEKMAICEFILYRTSKAGIYQPYY
                     KINLSKARISSIDFVTPHAVLEKELEPQERIAFIYEDISWEHTLAGTNAMSKWQDRVQ
                     "
     gene            20197..21111
                     /locus_tag="ACHY1N_003988"
     CDS             20197..21111
                     /locus_tag="ACHY1N_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046198.1"
                     /translation="MAGLRNNNNTQNAQWADYVGDILRGAQPINQLVPQHPYLNDVPL
                     IDELRHQNTHHVILLTLDVAKKILSPITSFDYIHFITTHPSGIKDTLAWLVNAGKLMT
                     EFDDNGKIIFNLNALKYTKASYFEILGEKYIKITTSSPWLLEKLGKYIFSSRAPQVLE
                     LAIGWRGALSESIKGVKFCIWFSVAWRTIEFIMSSERDLVNFLGDFSMDVAKAVIAGG
                     VATAIGSLASFACVSFGFPVILVGGAILLTGIVCTVVLNEIDAQCHLSEKLKYAIRDG
                     LKRQQELDKWKRENMTPFMYVLNTPPVI"
     gene            21121..>21327
                     /gene="ykfM"
                     /locus_tag="ACHY1N_003989"
     CDS             21121..>21327
                     /gene="ykfM"
                     /locus_tag="ACHY1N_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YkfM"
                     /protein_id="HFS4046199.1"
                     /translation="MRLHVKLKEFLSMFFMAILFFPAFNASLFFTGVKPLYSIIKCST
                     EIFYDWRMLILCFGFMSFSFLNIHV"
BASE COUNT         5116 a         5724 c         5803 g         4684 t
ORIGIN      
        1 attatatact tcaataagtt acataaaaaa tctatattta aattattgcc ataatacacc
       61 tgatgcgaat tgcacaggtt cacacaatct atttaacgct tgcagaatac ccctctttac
      121 gatcgataaa aagtcctttt cttatttatt ttgaagcgta aaattcgggg tgatgaagga
      181 gtggtgattt tattttcacc gccattaggg cggcattgcc gatatttttt tgcggtacaa
      241 atatgccgtg ttcatggcct gtacgagata acatgacgga tcacttttat gagcaaaaaa
      301 tttgaaggca gcgtcgcgcc tcgcgagcgt attaatatat cgtatgtccc aaaaacagat
      361 ggccagacgg ctgaagtgga acttccgctt aacatgctcg ttgtcggcga taccggaaat
      421 acgcaggaaa catccccact ggatgaacgt caggcagttt ccgttaacaa gcacaatttc
      481 ggtgcagtga tggctgaagc agccattggc ctcaatttta ctgtccccgc cacgctgaag
      541 ggaagcacaa cagacgatga actgaatgtg gcgctgaata tcaaatcact ggatgatttt
      601 tcaccagata gcgtggcccg gcaggttccg gaagtgaata aattgctgga actgcgtgaa
      661 gcactgactg cactgaaggg gccgatgggt aaccttccgg cattccgtac ccagctccag
      721 gcattgctgg aaaatgaaga gtcccgcgag cagttgctca aagaaatcgg tctggtgagc
      781 aataaataac caccactatt tcattaaaca gggttatcca ggcatgacgg cacacaaaaa
      841 tatctccgag acataccacc tctctgttgc agacattctg caggtggttt accaggtatg
      901 tttcagcccg tccgttgaaa tcaaccagga tggtgtggct gcgctgatta caacactgga
      961 tcgccgtatc agtgatctat tggatgagat tatccatttt tgtgagtttc agcagagcgc
     1021 gtcgcactgg cagcgcgtac ttcactgatg gcgaaaagcc ggtttcagaa acacagctaa
     1081 aacagaagga ttttcagtat gtctttacag gaagaggaac tcgtttccag tcatgccggg
     1141 cagcctgagc aggcatcgtc gctgcttgat caaatcatgg cacagacccg tattcagccc
     1201 ggttcggaag gttatgacgt tgcccgccag ggtgtgacag cctttattgc cagcatcctg
     1261 caatccactg catctgccga accggtcaat aaactggccg tggacagcat gattgcagat
     1321 attgatgaac gcatcagccg ccagatggat gtcatcatcc atgcgcctgc ctttcagcag
     1381 gtcgaatcgt tctggcgctc actgaaaacc atggtggatc gcgttgattt ccgtgaaaac
     1441 atcaaggtca acgtgcttca tgtcaccaag caggaacttc tggaagactt tgagtttgcg
     1501 ccagaaatta ttcagtccgg attttataag cacgtttatt cgtccggatt cggacagttt
     1561 ggtggtgaac ccatcgctgc cgtgctgggc gcttatgagt tcaaaaatac cgcacctgac
     1621 atgaaactgc tgcaatacgt cagtgccgtg ggcgcaatgg cgcacgcacc gttcctgtcc
     1681 tccgtttccc cggagtttat ggggctgaac tcgtggaccg aactgcctaa tatcaaagat
     1741 ctttatgcca tctttgaagg tccggcctac accaaatggc gcgccctgcg tgactcggaa
     1801 gattcgcgct atttagggct tactgcaccc cgcttcctgc ttcgccagcc ctggtcacca
     1861 gcagataacc ctgttaaaag ctttaactat cacgaagatg tcagccagaa ccacgaagat
     1921 tatctgtggg gtaatacggc ctggatgctg gcatgcaata tcgcagacag ttttgccaaa
     1981 taccgctggt gtccaaacat tatcggcccg caaagcggcg gcgcggtgaa agatctgccg
     2041 gtgcatctgt tcgaaacgat ggggcagatt caggccaaaa tcccaaccga ggtgctggtc
     2101 accgatcgcc gcgaatttga actggctgaa gagggtttta tcaccctgac catgcgtaaa
     2161 gactctgata atgcagcctt tttctctgca aactcggtac aaaaaccgaa gcactttccg
     2221 ggaaaagatg cagaaaccaa ctataagctg ggtacgcagc ttccttatct cttcatcatc
     2281 aaccggttag cgcactacat caaggtgttg cagcgtgaac aactggggtc atggaaagaa
     2341 aggagcgact tagagaggga gcttaatacc tggatccgtc agtatgttgc cgaccaggaa
     2401 aacccgcctg cggacgtgcg cagccgtaaa cctctgcgcg cagccagagt tgaggttatg
     2461 gatgtggaag gcgaacccgg ctggtaccag gttgcgctaa gcgtgaggcc tcattttaaa
     2521 tttatggggg caaattttga gctttccctg gttggccggt tagacaggga gtaacacacc
     2581 atgataccgg atcgggaaag aaccacaggt tctctttttg agcgtatgga agcctcttcg
     2641 gccagaaacc ggcagggagg cagtattcat tcgctcaggc aatccattcg ccagaaccta
     2701 cgaaacattc ttaatacccg gtccggtagt tgccggggtg cgcctgagct gggcattgat
     2761 gaaccggaag gggctgaaaa cttccgcgaa tccatgagtc gggccatcga gcaatgtata
     2821 gaacgctatg aaccccggat ctcacacgct gaagtgcagg cagtggtttc atccgcctcc
     2881 agcccgctgg atatgacgtt tcatattaca gcctgggtga catttaacga aacgcatgag
     2941 gtgcttgaat ttgatatggc accgaatggc agccagcatt accgggtgga ctgacaaatg
     3001 gaatttgaag aacgctattt ccgggaagaa ctcgattacc tgcgccagct tagcaagctg
     3061 ctggcaacgg aaaaacccca tctggcccgc ttcctggccg aaaaagatgc ggatccggat
     3121 attgaacgcc tgctggaagg ggtggctttt cttaccggca atctccgcca gaaaattgag
     3181 gatgaattcc cagaactgac gcacgggctt attaagatgc tatggcctaa ttacctgcgt
     3241 ccggttccgg caatgaccct tattgaatat acgccggata tggataagtc ttctgtaccg
     3301 gtgttaatcc cccgtaatga gcagtttaca accaacgccg gggaaatcag agttgatgaa
     3361 gtgctgccct ctgatgctaa aaaggaggag ccgcctccct gtaccttcac tctctgccgg
     3421 gatatctggc tgctgcccgt tcgcctggag cagattgaaa accgcagtac gacccgtaat
     3481 ggtgttatca acatcacctt ttcggtcgca ccgggaacgg acttccgcac gctggatctg
     3541 aacaaacttc gcttctggct cggcaatgac gacaactata cccgtgacca gctttattta
     3601 tggttctgcg aatacttgca gggtgccgac ctgactgtgg gtgaacagca tattcgcctg
     3661 cctgagttta tgctaaaagc tgtcggtttt gagccgcagg atgccatgct gccctggccg
     3721 aaaaacgtcc acagcggcta ccggatcctt caggagtatt tctgttaccc cgatgcgttt
     3781 ctcttttttg atctttgtgg ttgtccggct ttgcctgacg gattgcaggc ggaattcttt
     3841 accctgcaac tgcgtttttc gcgccctttg cccgtggaca tccggctgcg ccgcgattcc
     3901 ctgcgcctgt attgcgcacc tgccattaat ttatttatcc accatgcaga agccatcacg
     3961 ctggacaacc ggcgggcaga ctatccgctg gttcccagcc gccattaccc acaacattac
     4021 gatgtatttt ccgttaacag tgtggtgagc caggtccagg atatgttcag gaaaaaagat
     4081 ctggggcgtc ctgtttcgac gcaggccgcg cgccagtggc cagcctttga aagtttcagc
     4141 catcagatgg aatacagccg gaagcgggaa gtggtgtact ggcatcaccg gaccaaaaca
     4201 tccctgttcc atcgcggctt tgatcatacc cttgccttta tacatgctga tggcagttat
     4261 ccgtcagacg aatctctgct cagtaatgaa gtggtttcgg tatcgctgac ctgtaccaac
     4321 cgtgagcttc cgtcacaaat acgttccggc gatatcaccg gcacaaccgg taaaaatgcg
     4381 gctgttgctt catttcgcaa cattacccgc ccgacgcaac cactctggcc ggtcattgat
     4441 ggcagcctgc actggtccct actctccgcc atgaacctga attatctgtc attactggat
     4501 acggacgcgc tgaagcaggt catcgccaac tttgatcgcc acgcaatcca tcatccgcag
     4561 acggcacggc tgtcacaaca aaagctggat gccattgagc gtctggagac ccgccccgtt
     4621 gatcgcctgt ttacgggtat tcccgtccgg ggactggcct ccacgctgta tctgcacccg
     4681 gagccgtttg tctgtgaagg ggaaatgtat ctgctcggta cggtgctttc gcattttctg
     4741 tcgctgtacg ccagcgttaa ctcattccac atgctgaccg ttgtgaacac agaaagccag
     4801 gagacatgga aatggacgga aagaatcggg cagcatcctc ttatctgagt ccgggaaatc
     4861 ccccggcaga taaagagcag aatgatccgc tggcacaggt tttccataat gcctgctctt
     4921 acaatttttt tgcgatggcg gagctgttgc accgcctggc aaagggtgaa aaggggacgc
     4981 cagaattatc cctgcgtgac gatccggcac aggaaaccct gcgtttcagc gccgatgcca
     5041 gccttgcctt cccgtgcagt gatatcagtg cactgaaacg ggatacgtca ggggcattca
     5101 ggatgaccac cacctttatg gggttacagg ggagccagtc gcctctcccc ggttattacc
     5161 tcgatcacct ggcctggaaa gcggtacatg aacaaagtcc ggtaggtgat tttctggata
     5221 tgttcagcca ccgcctgacc cagtttgtct ggcatatctg gcgtaagtac cgctatcaca
     5281 tcagttttcg taacggcggt gtggatgcgt tctcgcagcg catgtactcc cttgtcgggc
     5341 tgggccaccg ccagcttcgc gataagctgg cgattaatca cagcaaaatg ctggcgtatt
     5401 ccgggatcct ggcaaatccg ggacgatccc cggaaataat ctgtggcctg gtgtcccact
     5461 gctttgattt gtcagaagtg acgctgcaaa actggcaacg tcgcaaggtg gatattgaac
     5521 cggatcagca aaatagtctg gggagctatt ctcttaaaaa tggcgaaaaa ctggcgggaa
     5581 gatcggtact gggcaacttt gttctgggta cacgagtgcc cgagctcagc ggaaaattcc
     5641 agctcagtat taccagcctg acccgaaaac agttcctctc ttttctgccg tccggcgaaa
     5701 acttcctgcc actgacgatg ttcgtgtcct tcatcctgcg cgatcagctt gcctgggact
     5761 tacatctggg gctggcgccg gagcaggtgg gcgcaatgcg cctgggcgat aacaaaagtg
     5821 cgctgctggg ctggaccagc ttcctcggca caccggaaga acgaccctca gtcaccatca
     5881 gggtacggtc gtaaattatg ataatcacgg agcagaatat gccggaagag aaactacaga
     5941 cgctttcatt gcaggtcatt aacggcagtg agctggaaag cggacgggcg gcgcgctgtc
     6001 tgttcacaca gcagggaaat gtcggccatg gccccgaatg ccactggtcg gtacaggatc
     6061 gtcagcagag cattccggcc caggctttta ccgttatcct gcacgatggc acattttgtc
     6121 tgcgcccgca gacggcacaa ctgtggctga atcaggcaaa agtcacagca acatcagacc
     6181 taatacagtt gcgccagggc gatgagatcc agatcggacg gctgatggtg agggttcatc
     6241 tgaaccgggg agatattccc cattacgatg aggaaatggc cactcccgaa accatcgtta
     6301 ccaatcgcga tatgctcacg gataccctgc tatcaacgga gggtacgcca cactatccgg
     6361 gaatgactca ccggcaccaa cttgcagaca ccgtggtaaa cggtttttct gccgatccac
     6421 tccaggcact tcagtccgaa agcctgatta ccacgggcga tccgctttca ggcattgcgg
     6481 ctgtccggcc atcggcaccg ctgtccgatc cggcaagtaa tggggggatc aatactccgt
     6541 ttatggatct gccgcccatt tatgccagcc ccggcgatcg taatgacgac gtctctgcgg
     6601 cagaaatggc gcaacgccac cttgcggtca cccccttact gcgcggtctt ggcggctcgc
     6661 ttaccatgag caattccgac gatgcggatg attttctgga ggaggccgga cgaacgttac
     6721 aggccgcaat aaaaggtctg ctcgatttgc agcagcagcg taacagcctc tcagacaaac
     6781 atttgcgccc gctggaagat aacccgctgc gcctgaacat ggattacgcc accgcgctcg
     6841 acgtaatgtt tgccgaaggt aaaagcccgg tacatctggc ggctcccgcc gccgtcagtg
     6901 aaagcctgcg caatgtccgc caccacgaag aagctaaccg ggcagcgatt gtggagtcgc
     6961 ttcgtgtcct gctggatgct ttctcaccac aaaatctgct gcgccgcttt gtgcagtacc
     7021 gccgcagcca tgaactgcgc cagccgctgg atgatgccgg agcatggcaa atgtacagcc
     7081 attattacga agaactggcc tccgatcgcc agcaggggtt tgagatgctg tttaacgagg
     7141 tctacgccca ggtctatgac cgggtgcttc gtgaaaaaca gcgggagccg gaagcatgaa
     7201 caggaaggcg tttctggcct gcgtgctgat gtgcgtcata ttaaccggct gcgaaacggc
     7261 gaaaaaaatc agtgaggtga tcaaaaaccc ggatatccag gtcgggagcc tgaaggagca
     7321 accttcggaa ataaccgtca ccctgctgac cgaaccggac accaatacca atgcggaagg
     7381 tgaatcagcc gccgtggatg tgcaactggt gtacctgact gacgactcaa aattgctggc
     7441 agccgactat gaccagatag ccagtacgcc gctaccggat gtgctgggta aaaactatat
     7501 cgaccaccag gatttcaacc tgttgccgga caccatcaaa accctgccgc cggtaaagct
     7561 ggatgagaaa acgcagttta ttggtgtcgt ggcctatttc tccgatgacc aggccactga
     7621 atggaaacaa atcgagacgg tggaaggaac cggccaccat taccgcctgc tggtgcatgt
     7681 acgtcaaagc agcatcgaaa tgaaaaaaga ggatgaataa ttatggcaac cacccgcaac
     7741 aaggtgatgt ggcaggaagg gatgctgatg cgcccacacc atttccagca acagcagcgt
     7801 tacaacgact acctggataa ccagcgtttc cgggccatga atgatttatc ctggggattt
     7861 accgaactca ccctcaacaa tgaactgctg gcgcagggta agatcatgat tgacagcgcg
     7921 tcaggcacac tgcccgacgg caccgtcttt tctatccccg accaggacgc actgcccgat
     7981 ccgctgcacc cgcaaaattt tccggacgaa agaagccgca atatctacct cgctctgccg
     8041 gtcgccagtg atgtgagaaa tgaaatcagc gacggacggc gaatcgggcg ttaccggctg
     8101 aattatgccg atgtccggga tttgcattca gaagaaggtg acgcgcgaac attgacgctg
     8161 ggtcaactga cgccgcgcat tatgagcggt gcagaagata tgagcgccta tattacgctc
     8221 ccgctttgcc gtatcagcga tcgccatgcc gatggctccc tgacgttgga tgacgatttt
     8281 atcccctcct gccagaatat tcaggtcagt aagaaactgc gtgtttatct caaagaggta
     8341 cagggggcca ttggcggacg ggcaagcgat ctggcaaacc gtattggctc tccggcgcag
     8401 agcggcatcg cggatgtggc ggaatttatg atgttgcagt tacttaaccg taaccagacc
     8461 cggtttaccc atcgcgcccg ccgatcccag ctccacccgg aagatttcta ccttgatctt
     8521 gctgggttgc tgggtgaact gatgaccttt accgagccgt cgcgcctgcc ctgcccgctt
     8581 gatgtgtatg atcatcatga tctgaccaaa acatttaaaa cactgttacc ggaagtcaaa
     8641 cgggcgctac ataccgtact gtcgccaaga gcggtcaatc tgccgctgca tctgcgtgac
     8701 ggtatctggc aggccgatat ccatgacaca gaactgctgc aatctgccac ctttgtgctg
     8761 gccgtggcgg caaacgtgcc ggtcgatcag atccagcgtc agtttatcca gcagtcgaaa
     8821 atttcctcgc cggaaaaaat ccgcaatatg gtcagtgtgc agatccccgg tattccattg
     8881 cgtgccctta tggtggctcc ccgccagctt ccttatcatt ccgggttcag ctatttcgaa
     8941 ctcgacaaga gcggacaggc ctggacagaa atggctgccg ccggggccgt tgcactgcat
     9001 gtatccggca gtttcccgga tctgaacatg caactgtggg cgataagagg gtaagacgat
     9061 ggatgagggg tcactgtctc tgccaccatt taccggatac gacgaaaaaa gccagcgcaa
     9121 ctaccatctc gcgcttcgtg gcaacagcct gaatccgatg atcgacgcgg ccacgccgct
     9181 actcggtatg gtaatgcgcc tttcaaccat gaacagccag acgatgccgg agcatctttt
     9241 tgctcaggtg gtgacggatg ttcaggccgt ggagcaactg cttcaggagc agggctacga
     9301 accgggcgtg attatctcgt ttcgctacat cccctgcacg tttattgatg aagcggcgct
     9361 cggtaacggc tggtcaaaca agaacgagtg gatcaagcag tcattgctgg tccatttcca
     9421 caacgaagcc tggggtggag agaaagtttt catcctgctg gagcgcctga tccgtgaacc
     9481 caaacgttac caggatctgc tggaatttct ctggatctgt ttttctctgg gatttcgcgg
     9541 gcgctacaaa gtggcagcac aggatcaggg ggaatttgag cagatctacc gccgtctgta
     9601 ccacgttctg cataaactgc gcggcgatgc ccctttcccg ctgttacacc aggacaaaaa
     9661 aacccagggc gggcgttatc agctcatcag tcgcctgact gttaaacata ttttttgtgg
     9721 tggcgttgtc gtgctggcgt tgttttacct gttctatctg ttgcgactgg acagccagac
     9781 gcaggacatc ctgcaccagc taaacaaatt acttcgataa ggacgtttat gatccagatt
     9841 gatcttccca cgctggtaaa acggctgaac ctgttctccc gccaggcgct ggagatggcc
     9901 gcctctgaat gtatgagtca gcaggcagcg gaaattaccg tcagccatgt gctcattcag
     9961 atgctcacca tgccacgcag tgacctgcgg gttattaccc gccagggcga tattggcatg
    10021 gaagagttgc gccaggcgct gacggtagag aactacacaa ccgcccgttc tgcggacagc
    10081 tacccggcgt tttccccgat gctggttgag tggctgaaag agggctggct gctggcgtcg
    10141 gctgagatgc agcacagcga actgcgcggc ggcgtgttgc tgctggccct gctgcattcg
    10201 ccgctgcgtt atataccgcc tgctgccgcc cggctgttga ccgtgaccgt ctgcaacagg
    10261 actttgtgca gtggacacag gagtcggcgg aatcagtcgt gccggatgca gacggtaaag
    10321 gcgcaggcac aatgacggac gcctctgaca ccctgcttgc ccgctatgcc aaaaacatga
    10381 ccgcagacgc ccgtaacggc aggcttgacc cggtactgtg ccgcgaccac gaaatcgacc
    10441 tgatgatcga cattctctgc cgccgccgta aaaacaaccc ggtggtggtg ggcgaagcgg
    10501 gcgtgggcaa aagcgcactg attgaagggc tggcgctgcg catcgtggca ggccaggtgc
    10561 cggacaagct gaaaaacacc gatatcatga cccttgacct gggcgcattg caggccgggg
    10621 cgtcggtgaa gggtgaattc gaaaaacgtt tcaaagggct gatggcggag gtcatttcct
    10681 ccccggtgcc ggtcattctg tttatcgacg aagcacatac cctgattggc gcgggcaacc
    10741 agcagggcgg gctggatatc tccaacctgc tcaaaccggc gctggcgcgc ggcgagctga
    10801 aaaccatcgc cgccaccacc tggagcgagt acaaaaaata cttcgaaaaa gatgccgccc
    10861 tgtcgcgccg cttccagttg gtgaaggtca gcgaacccaa cgctgccgaa gccaccatta
    10921 ttctgcgcgg tctgtcggcg gtctatgaac agtctcacgg cgtgctgatt gatgatgacg
    10981 ccttgcaggc cgctgcgaca ttaagcgagc gttatctctc cgggcgtcag ttaccggaca
    11041 aagcgattga tgtgctggat accgcctgcg cccgtgtggc catcaacctg tcgtcgccgc
    11101 cgaagcaaat ctcggcgctg accactctga gccaccagca ggaggcggaa attcgccagc
    11161 ttgagcgcga gcttcgcatc ggactgcgta ccgacacatc acggatgacc gaggtgctgg
    11221 tgcagtatga tgaaacgctg acggcgctgg atgaactgga agcggcctgg caccagcagc
    11281 agacgctggt ccgggagatt attgcgctgc gccagcagtt actgggcgtg gcagaggacg
    11341 atgcggcgcc gttgccggac gcagataccg tggaggatac gcagccagag tcagagtcag
    11401 aacaggataa taccggtgcc gtaccggctg atgaggccga cagagaacag ccggaagaga
    11461 ccgctgaaac agtttccccg gtacaacgtc tggcacatct cactgccgaa ctggacgccc
    11521 tgcataacga ccggttgctg gtttccccgc acgtcgataa aaaacagatt gcggcggtga
    11581 ttgccgaatg gaccggcgtg ccgcttaacc gcctgtcgca gaatgaaatg tcggtcatca
    11641 ccgacctgcc aaaatggctc ggcgacacca tcaaaggcca ggacctggcg attgccagcc
    11701 tgcacaaaca cctgctgacc gcacgcgccg acctgcgccg tccgggacgc ccgctgggcg
    11761 cgttcctgct ggctggcccc agcggcgtgg gtaaaactga aaccgtcctg caactggcag
    11821 agctgctcta cggcggtcgc cagtacctga ccaccatcaa tatgtccgag ttccaggaga
    11881 aacataccgt ctcgcgactg attggttcgc ctccgggcta cgttggctac ggtgaaggcg
    11941 gcgtactgac cgaagcgatt cgccagaaac cctactcggt agtactgctc gatgaagtgg
    12001 aaaaagcgca cccggatgtg ctcaacctgt tctaccaggc gttcgataag ggcgaaatgg
    12061 cagacggtga aggccgcctg attgactgca aaaatatcgt cttcttcctg acgtccaacc
    12121 tcggctacca ggtaatagtc gagcatgccg atgacccgga aaccatgcag gaagtactgt
    12181 atccggtgct ggccgacttc ttcaaacctg ccctgctggc gcgtatggaa gtggtgccgt
    12241 acctgccgct gtcgaaagag acgctcgcca ccatcattgc cgggaaactg gcccgcctgg
    12301 ataacgtgct gcgcagccgc tttggcgcgg aggtgattat agaaccggaa gtgacggacg
    12361 aaatcatgag ccgcgtcacc cgcgcggaaa acggcgcgag gatgctggaa tcggtcatcg
    12421 acggcaatat gctgccgccg ctctccctgc tgctgttgca gaaaatggcg gcgaatacgg
    12481 cggttgcccg gattcggttg tcggcagtgg acggcgcatt tacggcagac gtggaagatg
    12541 ctcagaacga cgagtccgtc acaaaggatg aaacggtttt atgagcaggt tgcgcgtttt
    12601 ccggcagaca ggatggttta tcgcgggcct gatgacgggc ttacccgcca ctgccgcgcc
    12661 cgcagaagca tcgtcaatgg ccggtgtggc ggtcgccgtc gccaccacga ccccgccgga
    12721 tgcgacagcc acgttacagg ccatgcagtc ctgtcggcgg gagtccgcgg cgctggagcg
    12781 gcttgactgc tatgaccgcc tgctggcacc gctgtccccg tcagggtttg acggggcgct
    12841 ggtcaaagcc ggttttgtgg gcgaagcctg gacccgcgcc acggaacagg aaaaacaccg
    12901 ccagggcaac accacagagc tgctggtgac gcaggtgccg ggggagcgcc cgacggtggt
    12961 gataaccacc ccggctatcg gtcatgttcc gccacgcccg gtgctgatgt tcagttgcgt
    13021 ggacaatatc acccggatgc aggtggcgct gatgcaccct ctggatgtcc atgatatcgc
    13081 cgtcactctg aatgccgaca accgggcatt gcgcagccac tggtttgtgc gcgagaacgg
    13141 caccctgctg gagtccagcc gggggttatc cgggattgat gaaattaagc aactgttcgg
    13201 cgcaaaaacg ctgacggtgg ataccggcgc agacaatgcc gccggaaagc tgacctttaa
    13261 cattgacggg ctggcaaggg cgattgctcc cctgcgcgat gcctgccact gggcgggaga
    13321 ataaaaatat ggcaatggac ttacgcgatc cgaatgtctg gatatcgcac ctgctggaaa
    13381 acctgccgga agagaaactg gcatcggcgc tgaaagatga caacccgaac tgggagtata
    13441 tcgacggcga aatcgtcaag ctgggatcgc tggcccacag tcaactggat atcccggaac
    13501 tccagcgccg ggggctggtc attctggctt cggagagtaa ggattttcgt ctgctggcgc
    13561 atctgctgag aaccctgcaa cacgccggtg atcctcatct cgcattgcgc ctgctggcgc
    13621 tgtatgtgga gcattactgg gcggtggctg cgccgcagaa tatggcgcat aaaaaacgct
    13681 ttgccagcca ggtcattaaa cgctttgaaa caggtattga agttttttca cagaacgccg
    13741 ccacagcgca gcgcgatgcg ctgtcagggg aactggcaaa actggcgcaa tgctggcagt
    13801 cacataacgc cccggaactg gcacaggcta ctgatgatct ttttgccctg taccagcgtg
    13861 cgtttaatcg tgcggcaccg gctcctgtcc ccactccggc ggcctccggt agttcaccac
    13921 agaccaccgc cacgtctgaa agcggcgtga cgcaacccag tgctccggct ccccaaatcg
    13981 tcatcgacag tcacgacgac aaagcctggc gcgacacgct gttaaaagtg gcggccattt
    14041 tatgtgaacg ccagccggat tcaccgcagg gctaccgtct gcgccgccat gcgctttggc
    14101 agaacatcac cagtacgccc caggcggaaa gcgatggccg tactccactg gctgcggtct
    14161 ccgccgatat ggtggcagat taccatgctc agctcggtag tgccgatatg gcgctgtggc
    14221 agcaggtgga gaaaagcgta ctgctggctc cttactggct ggatggtcac tgcctttctg
    14281 cacagacggc gctgcgtctg ggttacaaac aggtggcaga cgccatccgc gatgaggtca
    14341 tccgcttcct tgagcgtctg ccccagctta ccgggctgct gtttaatgac cacacaccgt
    14401 ttatcagtga gcagacgaaa caatggctgg cagcttcgcc cgacgccaaa gttgcaccgg
    14461 ttgcgcaaat cggtgaggaa tcgaaggcag ccagagcctg ttttgctgag cagggtctgg
    14521 aggcggcgct gcgatatctg gacatgctac ccgaaggcga tccccgcgat cagtttcacc
    14581 gccagtacct tgccgcacag ttgacggaag aggcggggct ggtacagctt gcgcagcagc
    14641 agtaccggat gttgttcagg atgggattgc agatgatggt ggcagactgg gagccgtccc
    14701 tgcttgagca gctagaacaa aaattcacgg cagaacaata aaagagaaca ggagtttttg
    14761 tgttcagatt accaacaccc cgactactca gcggactcaa atcagccctg cgaccggcga
    14821 tgccccggtt taaagtctct gctttctggc tgctgatact ggcgtggatt tttctgctgg
    14881 tgtggatctg gtggaaaggc ccgacgtgga cgctgtatga agaacagtgg ctcaaaccac
    14941 tggcgaaccg ctggctggca acggcggcgt gggggattat tgccctgatg tggcttaccg
    15001 tccgggtgat gaagcgcctg caacagcttg aaaaacagca aaaacaacag cgcgaggaag
    15061 ccattgatcc gctcagtgtg gaactgaacg cccagcagcg ttacctcgac cgctggctgc
    15121 tgcgcctgca acgccatctc gacaaccgcc gtttcctgtg gcaattgccg tggtatatgg
    15181 tcatcggccc ggcgggcagt ggcaaaacga cactgctgcg cgaggggttt ccgtcagaca
    15241 ttatttatgc cccggagggc tcgcgcggcg cagaacaacg cctgtacctt acgccccatg
    15301 tcggtaaaca ggcggtgatc tttgatatcg acggcacact ctgcgctccc gctgatgcgg
    15361 atatcctgca tcgccgtctg tgggaacata ccctcggctg gctgaaggaa aagcgcgcgc
    15421 gccagccgct gaacgggatt attctgacac tcgatttacc cgatctgctg accgcagaca
    15481 agcgccgccg tgagtatctg ctacagacgc tgcgcagccg cttgcaggat atacgccagc
    15541 atcttcactg ccagctaccg gtttacgtgg tactgacccg gcttgattta ttgcagggtt
    15601 ttgccgccct gttccagtcc ctgaacagac aggatcgtga tgcgattctg ggtgtcacgt
    15661 tcacccgccg tgcccatgaa aatgatgact ggcgaacaga gttgaatgct ttctggcaga
    15721 catgggtgga tcgaatgaat ctggcgttgc cggatctgat ggtcgctcag actcacaccc
    15781 gcgcgtcttt attcagtttt tcccgccaga tgcagggaag ccgtgaaccc ctggtgtcac
    15841 tgcttgaagg tctgcttgac ggcgaaaata tgaacgtgat gctgcgtggt gtctatctca
    15901 cctcgtcact gcaacgcggc cagatggatg acatctttac ccagtccgcc gcccgccagt
    15961 accggctggg caataaccca ctggcgtcct ggcccctggt ggacaccgcg ccttatttca
    16021 cccgcagcct gttcccgcag gcattactcg cagagcctaa tctggcaacg gagagccgtg
    16081 actggctgat gcgttcccgt cgccgcctga cggttttctc tgccacaggc ggcgtggcgg
    16141 cactgctgct catcaccggc tggcatcact attacaacgg taactatcag tccggcatca
    16201 ccgtgcttaa gcaggccaaa gcctttatgg acgtgccgcc tccgcagggg aaagacgact
    16261 acggcaacct gcaactgccg ctgctgaacc cggtacgcga tgccacactg gcctatggcg
    16321 actggggcga ccgcagccgt ctggccgata tgggactgta ccagggacga cgtatcgggc
    16381 cttatgtgga acagacctat ctgcaactac tagagcagcg ttacctgccc tcgctgttta
    16441 acgggctggt caaagcgatg aacgccgcgc cgccggagag tgaggaaaaa ctcgccgtgc
    16501 tgcgcgtgat gcgaatgctg gaggacaaaa gcggacgcaa taatgaggtg gtgaagcagt
    16561 atatggcaaa acgctggagc gaaaagttcc acggccagcg tgatatccag gcacaactga
    16621 tgtcccatct tgactacgcg ctggctcata ctgactggca tgcagagcgt caggcgggcg
    16681 acggtgacgc catcagccgc tggatgccat atgacaagcc cgtggtatca gcacagaaag
    16741 aactgagcaa actgcctgtc taccagcggg tttaccagag cctgaaaacg cgggcgctgg
    16801 gcgttctacc tgctgacctc aatctgcgtg accaggtagg gccaaccttt gaccaggtct
    16861 ttacatctgc cgatgacaac aaactggttg ttccacagtt tcttacccgt tacggcctgc
    16921 aaagctattt tgtaaaacag cgcgatgaac tggttgaact gacggcaatg gattcctggg
    16981 tactcaacct cacccgcagt gtgaaataca gtgacgccga ccgcgcggaa atccagcgcc
    17041 agttgaccga gcagtatatc agcgactaca ccgctacctg gcgagccggg atggacaatc
    17101 tgaatatccg caattttgag tccattggac aactgaccgg ggcgctggag caggttatca
    17161 gcggcgacca gcctttgcag cgggcgctga ctgtgttgcg tgacaacaca cagccaggcg
    17221 tcttttctga aaaactttct gccaaagaac gggatgaggc tctggcagaa ccggactacc
    17281 agttgctcac ccgcctcggg catgaatttg ccccggaaaa cagtactctg gcagtacaga
    17341 aagacaaaga aagcacgatg caggccgtgt atcagcaact caccgagttg caccgctatc
    17401 tgctggcaat tcagaacgcg cctgtaccag ggaaatcggc gctgaaagcc gtgcagttgc
    17461 ggcttgatca gaacagcagc gatccgatat tcgccacccg ccagatggca aagacactgc
    17521 ctgctccgct caaccgctgg gttggcagac tggctgacca ggcctggcat gtggtgatgg
    17581 tggaggccgt tcactatatg gaagtggact ggcgcgacag cgtggtgaaa ccgtttaacg
    17641 agcaactggc aaataactat ccgtttaatc cgcgttctgc acaggatgcc tcactggatg
    17701 ccttcgaacg cttctttaaa ccggatggca tactggatac cttctaccag cagaacctga
    17761 agctgtttat cgacaatgac ctgagtctgg aggatggcga taacagcgtc attattcgcg
    17821 aagatattat tgcgcaactg aaaaccgcgc agaaaatccg tgacatcttc ttcagtaaac
    17881 agaacggtct gggaacatcc tttgccgtgg aaacggtatc gctctccggc aacaaacgcc
    17941 gcagtgtact gaaccttgac ggccagttag tcgattacag ccaggggcgc aactataccg
    18001 cccatctggt ctggcctaac aatatgcgcg aaggcaacga aagcaaactg acgctcatcg
    18061 gcaccagcgg caacgcaccg cgcagtatca gcttcagcgg gccgtgggcg cagttccgcc
    18121 ttttcggggc cggacaactg accggagttc aggatggcaa ctttaccgtg cgctttagcg
    18181 tggacgctgg cgcgatgacc taccgtgtgc ataccgacac tgaggataac ccattcagcg
    18241 gtgggttatt cagccagttt ggtctgtcag acacactgta ctgaggaggc agggatggat
    18301 agtaacggac tgacacaaac tatcgttacc ggcagtgacc cgcgcgggct gccggaattc
    18361 agtgccatcc gcgaggaaat aaacaaagcc agccacccgt cacagcctga gctgaactgg
    18421 aaactggtgg agtcgctggc actggcgatt tttaaagcca acggtgtgga tttacacacc
    18481 gccacctact atacgcttgc ccggacacgg acacagggac tggcgggatt ctgcgaaggt
    18541 gcggaactgc tggcggcaat ggtaagccac gactgggata agttctggcc gcagggcggc
    18601 ccggcgcgta ctgaaatgct ggactggttt aactcccgaa ccggcaatat tctgcgtcag
    18661 caaatctcct ttgcggaatc cgacctacca ctgatctacc gcacagagcg ggcattgcag
    18721 cttatctgcg ataagctcca gcaggtggaa ctgaagcgcg ttccgcgcgt ggagaatctg
    18781 ctctatttta tgcagaacac gcgtaaacgg cttgaacccc agctgaagag taacactgag
    18841 aacgccgcac agaccacggt cagaacgctg atttatgccc cggaaacaca ggcatcttcc
    18901 acaccagaag cggtagtgcc tcccctgccc ggcctgcctg agatgaaagt ggaagtgcgc
    18961 agtctgacag agaatccccc acaggccagt gtgataaagc aaggcagtac ggtaagaggg
    19021 tttatcgcag ggatcgcctg ttcagtggct gtcgcctcag cattgtggtg gtggcaggtc
    19081 tatccggtgc agcagcaact gttacaggtt aacgacaccg ctcagggcgc agcaacggtg
    19141 tggatggcct cacctgaact cgaaaactat gagcgcaggc tgcaacaact tcttgatacc
    19201 tccccggtac agccgctgga aaccgggatg cagatgatgc gtgttgccga cagtcgctgg
    19261 ccggaaagcc tgcaacagca acaggcctcg acacaatgga atgaggcact caaaacccgc
    19321 gcacagagta gcccgcagtt gcgtggctgg ttgcagaccc gccaggactt acatgctttt
    19381 gcagatctag tgatgcagcg cgagaaagag ggactaaccc tttcctatat caaaaatgtc
    19441 atctggcagg cggagcgggg actggggcag gaaacacccg ttgagtctct gttgacgcag
    19501 taccaggatg cccgtgcgca gaagcagaat acagatgcgc tggaaaaaca aattaatgag
    19561 cgactcgaag gcgtgttaag ccgctggctg ctgctgaaga ataacgtcat gccagaggcg
    19621 gcaaccggta ccacggccga aaaataatta tttaattaaa ggagattatc atggcaaata
    19681 taagttattt atctttgagt ggagagacac aagggctgat ttcagcaggt tgctcaacgc
    19741 ttgattctgt cggaaacaaa gcgcagccag aacataaaga tcagatcatg gtttatgcgt
    19801 taatgcattc catctcaaga agtcaaaatg tcaatcatca tgaattaatt atcaccaaac
    19861 cggttgataa atcctcacca ttgctggcaa aagcacttag tgacaatgaa aaaatggcaa
    19921 tatgtgaatt tatactctac cgaaccagta aagcgggtat ttaccagcct tattataaaa
    19981 taaatctgtc aaaagcccga atatcaagta ttgattttgt cacaccgcat gctgtcctgg
    20041 aaaaagaact ggaaccacag gagagaattg cctttattta tgaagatatt tcctgggagc
    20101 atacgttagc cggtacgaat gcaatgagta aatggcagga tcgtgtacag taacttactg
    20161 taataacata ataaattact attgcggaga gataaaatgg ctggtttaag gaataacaac
    20221 aacacacaga atgcacagtg ggctgattat gtgggtgaca ttcttcgggg ggctcagccg
    20281 ataaaccagc tagtacctca gcacccttat cttaacgacg tcccactcat tgatgagtta
    20341 aggcatcaga acactcatca tgttattctc ttgacacttg atgttgcaaa aaaaatactc
    20401 agcccaataa catcatttga ttacattcat tttatcacta cacatccttc aggtataaaa
    20461 gatacactcg cctggttagt taacgcgggt aaattaatga ctgagtttga tgacaatggg
    20521 aaaattatat ttaaccttaa tgccttaaag tatacaaaag caagttactt tgaaatactt
    20581 ggagagaaat atataaaaat cacaacatcc agcccctggc ttttagaaaa gctcggtaaa
    20641 tatattttct cttcacgagc gcctcaagtt ctggaactcg ctattggctg gcgaggagct
    20701 ttatctgaat caataaaagg agttaagttc tgtatctggt tttcagtagc ctggagaacc
    20761 atagaattta ttatgagttc agagcgagat ctggttaatt ttcttggcga tttttcaatg
    20821 gatgtggcca aagcagttat agccggtggt gttgcaaccg ctattggaag cctggcttct
    20881 tttgcctgtg ttagctttgg ctttccagta attcttgtcg gaggagcaat tttactgaca
    20941 gggatagtgt gtacagttgt tttaaatgaa atcgatgctc aatgccattt atcagaaaaa
    21001 ttaaaatatg caattagaga tggactaaaa cggcaacagg aacttgataa atggaaaagg
    21061 gaaaacatga ctccatttat gtatgttctt aacactccac ccgtgatatg aggattaacc
    21121 atgcgtttac atgttaaatt aaaagagttt ctttcgatgt tttttatggc catattattt
    21181 ttccctgcat tcaatgcttc tttgtttttt accggagtta aacctctata ttcaataata
    21241 aaatgctcca cggaaatatt ttatgattgg agaatgttga ttctgtgctt tggtttcatg
    21301 tcgttttcct ttttaaatat tcatgta
//
LOCUS       DAZUDJ010000077        20594 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.077, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000077 DAZUDJ010000000
VERSION     DAZUDJ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20594
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.077"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(201..2192)
                     /gene="tkt"
                     /locus_tag="ACHY1N_003990"
     CDS             complement(201..2192)
                     /gene="tkt"
                     /locus_tag="ACHY1N_003990"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFS4046200.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDG
                     HDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMP
                     SDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVG
                     LNGAIIGMTTFGESAPAELLFEEFGFTVDNVVAKAKELL"
     gene            2470..3228
                     /gene="loiP"
                     /locus_tag="ACHY1N_003991"
                     /gene_synonym="yggG"
     CDS             2470..3228
                     /gene="loiP"
                     /locus_tag="ACHY1N_003991"
                     /gene_synonym="yggG"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease LoiP"
                     /protein_id="HFS4046201.1"
                     /translation="MKIRALLVAMSVATVLTGCQNMDSNGLLSSGAEAFQAYSLSDAQ
                     VKTLSDQACQEMDSKATIAPANSEYAKRLTTIANALGNNINGQPVNYKVYMAKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVIGHEMGHVALGHVKKGMQVALGTNAVRVAAASA
                     GGIVGSLSQSQLGDLGEKLVNSQFSQRQEAEADDYSYDLLRQRGISPAGLATSFEKLA
                     KLEEGRQSSMFDDHPASAERAQHIRDRMSADGIK"
     gene            complement(3314..4876)
                     /locus_tag="ACHY1N_003992"
     CDS             complement(3314..4876)
                     /locus_tag="ACHY1N_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HFS4046202.1"
                     /translation="MERTLPWKPLLCLLFLLSTGCDRAEKQKIAAQLQQDKEAISSVV
                     KKSYRALCGPEFVTSTDSHDRLAEMQQVFTPALMEPVLKYWQESPKTCKRRFPSYSDP
                     LATFVEGDKAQIGAFFGHQSYIDIPMELIREGDGKWKIAAIDFASLHEFEKNGRVTDE
                     VQKKIDLLKKRSFKQHRDFPLLTRTAPERVSNSPLTSVEQTVTEPDSSWLDVLLTIGK
                     YALYLVAIILILALVAVLWIGYGLVFAGHRLFKASCKDPSIQKIPAAERWAMAVGAPY
                     AIAGNNHWARRVVNDDSVEAENDCKSEVESLADMWGVFDRDSLLEQLLALFVAGHRSV
                     YAEQIKNDSEMPDAEYRAFAQQLAQNAKSSSEAKERLWQLQMVRKNRRKICDIDFCAW
                     DMVRFVMLCNSGAQVGYITQREMVDFSMLAARRVQQHYRSWRELAGHFLLARWYWKAT
                     DKRHLITHILFKKAITSLLKEQGSPWRTLPWDTPLPEGTETAFAWACGVSTADVVEVQ
                     PDTPDKAIYEAN"
     gene            complement(5027..5947)
                     /gene="speB"
                     /locus_tag="ACHY1N_003993"
     CDS             complement(5027..5947)
                     /gene="speB"
                     /locus_tag="ACHY1N_003993"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HFS4046203.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(6084..8060)
                     /gene="speA"
                     /locus_tag="ACHY1N_003994"
     CDS             complement(6084..8060)
                     /gene="speA"
                     /locus_tag="ACHY1N_003994"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008792 - arginine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HFS4046204.1"
                     /translation="MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAE
                     DAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGTFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQF
                     RDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE"
     gene            complement(8069..8200)
                     /gene="yqgB"
                     /locus_tag="ACHY1N_003995"
     CDS             complement(8069..8200)
                     /gene="yqgB"
                     /locus_tag="ACHY1N_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HFS4046205.1"
                     /translation="MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII"
     gene            complement(8294..8437)
                     /gene="yqgG"
                     /locus_tag="ACHY1N_003996"
     CDS             complement(8294..8437)
                     /gene="yqgG"
                     /locus_tag="ACHY1N_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YqgG"
                     /protein_id="HFS4046206.1"
                     /translation="MNRCLLLNLSHRSGEDSFPALCISALHTCRCYTHLGASQDSRAG
                     YSY"
     gene            complement(8548..8799)
                     /gene="yqgD"
                     /locus_tag="ACHY1N_003997"
     CDS             complement(8548..8799)
                     /gene="yqgD"
                     /locus_tag="ACHY1N_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YqgD"
                     /protein_id="HFS4046207.1"
                     /translation="MVADPTTTLQVKNTGSLSVNRYGWINIWMAILGQFFTRFPLFFE
                     SCLILLKTWLEIFPDNAGILRIYLLQFSAIVGYKTRRAA"
     gene            8855..10009
                     /gene="metK"
                     /locus_tag="ACHY1N_003998"
     CDS             8855..10009
                     /gene="metK"
                     /locus_tag="ACHY1N_003998"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFS4046208.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLT
                     SATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK"
     gene            10445..11839
                     /gene="galP"
                     /locus_tag="ACHY1N_003999"
     CDS             10445..11839
                     /gene="galP"
                     /locus_tag="ACHY1N_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/proton symporter"
                     /protein_id="HFS4046209.1"
                     /translation="MPDAKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIA
                     DEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVL
                     GTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
     gene            11916..12413
                     /locus_tag="ACHY1N_004000"
     CDS             11916..12413
                     /locus_tag="ACHY1N_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HFS4046210.1"
                     /translation="MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRG
                     TSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWM
                     MESVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGE
                     QLVAK"
     gene            12508..13215
                     /gene="endA"
                     /locus_tag="ACHY1N_004001"
     CDS             12508..13215
                     /gene="endA"
                     /locus_tag="ACHY1N_004001"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HFS4046211.1"
                     /translation="MYRYLSIAAVVLSAAFSGPALAESINSFSQAKAAAVKVHADAPG
                     TFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRVEWEHVVPAWQFGHQRQCWQDGG
                     RKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEK
                     AAEPPARARGAIARTYFYMRDQYNLTLSRQQTQLFNAWNKMYPVTDWECERDERIAKV
                     QGNHNPYVQRACQARKS"
     gene            13295..14026
                     /gene="rsmE"
                     /locus_tag="ACHY1N_004002"
     CDS             13295..14026
                     /gene="rsmE"
                     /locus_tag="ACHY1N_004002"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311849.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFS4046212.1"
                     /translation="MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFD
                     GSNQVFDAEITSASKKSVEVKVLEGKIDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWC
                     AEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            14039..14989
                     /gene="gshB"
                     /locus_tag="ACHY1N_004003"
     CDS             14039..14989
                     /gene="gshB"
                     /locus_tag="ACHY1N_004003"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004363 - glutathione synthase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HFS4046213.1"
                     /translation="MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLY
                     LINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYIL
                     ERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILK
                     PLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIG
                     DRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ"
     gene            15098..15661
                     /locus_tag="ACHY1N_004004"
     CDS             15098..15661
                     /locus_tag="ACHY1N_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417423.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HFS4046214.1"
                     /translation="MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLE
                     NLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDN
                     TVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKT
                     PIADRWREAAKLIGVDILTMPGVAGHA"
     gene            15661..16077
                     /gene="ruvX"
                     /locus_tag="ACHY1N_004005"
     CDS             15661..16077
                     /gene="ruvX"
                     /locus_tag="ACHY1N_004005"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFS4046215.1"
                     /translation="MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNL
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVE
                     ARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY"
     gene            complement(16266..17246)
                     /locus_tag="ACHY1N_004006"
     CDS             complement(16266..17246)
                     /locus_tag="ACHY1N_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HFS4046216.1"
                     /translation="MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGRMEAAPFDAPDV
                     EELLREWLDDDQRAILLENGQLDFAVSLAENQRLRGSAFAQRQGISLALRLLPSHCPQ
                     LEQLGAPTVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVE
                     YIYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVAL
                     FELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMITFQQSYQQRVGEGRL"
     gene            17264..17968
                     /gene="yggS"
                     /locus_tag="ACHY1N_004007"
     CDS             17264..17968
                     /gene="yggS"
                     /locus_tag="ACHY1N_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate homeostasis protein"
                     /protein_id="HFS4046217.1"
                     /translation="MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIA
                     EAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRL
                     RGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYSKK"
     gene            17986..18552
                     /gene="yggT"
                     /locus_tag="ACHY1N_004008"
     CDS             17986..18552
                     /gene="yggT"
                     /locus_tag="ACHY1N_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic shock tolerance protein YggT"
                     /protein_id="HFS4046218.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVT
                     QPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVL
                     LLYVINMGVAEVLQATGNMLLPGLWMAL"
     gene            18549..18839
                     /gene="yggU"
                     /locus_tag="ACHY1N_004009"
     CDS             18549..18839
                     /gene="yggU"
                     /locus_tag="ACHY1N_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417428.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF167 family protein YggU"
                     /protein_id="HFS4046219.1"
                     /translation="MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN"
     gene            18847..19440
                     /locus_tag="ACHY1N_004010"
     CDS             18847..19440
                     /locus_tag="ACHY1N_004010"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HFS4046220.1"
                     /translation="MQKVVLATGNAGKVRELASLLSDFGLDIVAQTDLGVDSAEETGL
                     TFIENAILKARHAAKVTGLPAIADDSGLAVDALGGAPGIYSARYSGEDATDQKNLQKL
                     LETLKDVPDDQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            19433..20569
                     /gene="hemW"
                     /locus_tag="ACHY1N_004011"
     CDS             19433..20569
                     /gene="hemW"
                     /locus_tag="ACHY1N_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFS4046221.1"
                     /translation="MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     CDLDNDVAYAQGREVKTIFIGGGTPSLLSGPAMQTLLDGVRARLPLAADAEITMEANP
                     GTVEADRFVDYQRAGVNRISIGVQSFSEDKLKRLGRIHGPQEAKRAAKLASGLGLRSF
                     NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPSYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDG
                     RILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLEAAPRVEFIAYTGLC
                     EDVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE"
BASE COUNT         4997 a         5424 c         5256 g         4917 t
ORIGIN      
        1 ttaatttctt atataacatt gagttataga tataacaaca aatgtcaata cgcatatcgt
       61 gatgcatatt acataattga tatttattgc atataaatat ttgtgatcta caacacgctt
      121 tatctattgc ttgtccgcaa acggacatat caaggtaata aaaaaggtcg ccgaagcgac
      181 ctttttaccc gaaatgctaa ttacagcagt tcttttgctt tcgcaacgac gttgtcgacg
      241 gtgaagccga actcttcgaa cagcaactct gccggagctg actcaccgaa ggtggtcata
      301 ccgatgatag cgccattcag gccaacatac ttgtaccagt agtcagcaat acccgcttct
      361 accgcaacgc gtgcagtaac cgctttcggc agtacggatt cacggtaagc agcatcctgc
      421 ttgtcaaatg cgtcggtaga cggcatggac accacgcgcg ctttcacgcc ttcggcagtc
      481 agtttttcgt aggcagcaac agccagttca acttctgaac cggtagcgat gaaaatcagt
      541 tccggctgac cggcgcagtc tttcagcaca taaccaccgc gcgcgatgtt tgccagttgc
      601 tcttcagttc gttcctgctg cgccaggttc tgacgggaga ggatcagtgc ggtcgggccg
      661 tcctgacgct caacaccgta tttccacgcg accgcggatt caacctggtc acacggacgc
      721 catgtagaca tgttcggggt tacgcgcaga gaagcgacct gctcaaccgg ctggtgagtc
      781 gggccgtctt cgcccagacc gatggagtcg tgggtgtaaa ccatcacctg acgctgtttc
      841 atcagcgcag ccatacgtac ggcgttacgt gcgtattcca cgaacatcag gaaggtggag
      901 gtgtacggca ggaaaccacc gtgcagggag ataccgttag caatcgcggt cataccgaac
      961 tcgcgaacac cgtagtggat gtagttaccc gcagcatctt cgttgattgc tttagaacca
     1021 gaccacaggg tcaggttaga cggtgccagg tcagcggagc cgccgaggaa ttccggcaac
     1081 agcgggccga acgcttcaat agcattctga gacgctttac ggctggcgat tttcgccgga
     1141 ttagcctgca gtttagcgat aaactctttc gctttggcgt cgaagtcaga cggcatttcg
     1201 cctttcatac ggcgggtaaa ttcagccgct tcctgcggat aagctttcgc gtaagccgca
     1261 aacttctcat tccatgcaga ttctttcgcc tggcctgctt ctttcgcatc ccactgcgca
     1321 tagatttcag acgggatttc gaacggtgcg tatttccagc ccagctgttc gcgggtcaga
     1381 gcgatttctg catcacccag cggcgcaccg tgggagtcgt gagtaccggc tttgttcggg
     1441 gaaccgaaac cgatgatggt tttgcacatc agcagggacg gtttgtcagt cactgcgcgc
     1501 gcttcttcta ctgcgcgttt gatggatgct gcgtcatgac cgtcgatgtc gcgaataacg
     1561 tgccagccgt aagcttcgaa acgcattgcg gtgtcgtcgg tgaaccagcc ttcaacgtga
     1621 ccatcaatag agataccgtt gtcatcgtag aacgcaatca gtttacccag cttcagcgta
     1681 cccgccagag agcaaacttc gtgggagatg ccttccatca tgcagccgtc gcccatgaag
     1741 gcgtaggtgt agtggtcgac aatgtcgtgg cccggacggt taaactgcgc cgccagcgtt
     1801 ttttctgcaa tcgccatacc gactgcgttg gcaataccct gacccagcgg accggtggtg
     1861 gtttccacac cagcggtata acctacttcc gggtggcccg gagttttaga gtgcagctga
     1921 cggaagtttt tcagttcttc catcggcaga tcgtaaccgg tgaggtgcag caggctgtag
     1981 atcagcatgg agccgtggcc gttggacagc acgaagcggt cacggtcagc ccaggacgga
     2041 ttctgcgggt tgtgtttcag gaaatcacgc cacaggactt cggcaatgtc agccataccc
     2101 ataggggcac ccgggtgacc ggatttggct ttctgtactg cgtccatgct cagcgcacga
     2161 atagcattgg caagctcttt acgtgaggac attttgactc cagatcggat gatgaagggc
     2221 acgcccttaa cgacttgacg acagcgcgtt ttgggctacg ccggaaaatt tgccaacaat
     2281 ttaccgcaag ccgcgcgtca tgtacatgga acatcctttt gccgcttcag aaatctctgg
     2341 atcatgctcg catgttgcgc aatctactcg cccgtccgct gcgcttttcc ttatactgag
     2401 actgagcgtc ggttcacctg caaacggcgc atttttagaa taatcctgac cttgtgcgga
     2461 agaaaaaaca tgaaaattcg cgccttattg gtagcaatga gcgtggcaac ggtactgacc
     2521 ggttgccaga atatggactc caacggactg ctctcatcag gagcggaagc ttttcaggct
     2581 tacagtttga gtgatgcgca ggtgaaaacc ctgagcgatc aggcatgtca ggagatggac
     2641 agcaaggcga cgattgcgcc agccaatagc gaatacgcta aacgtctgac aactattgcc
     2701 aatgcgctag gcaacaatat caacggtcag ccagtgaatt acaaagtgta tatggcgaag
     2761 gatgtgaacg cctttgcaat ggctaacggc tgtatccgcg tctatagcgg gctgatggat
     2821 atgatgacgg ataacgaagt cgaagcggtg atcggtcacg agatggggca cgtggcgtta
     2881 ggccatgtga agaaagggat gcaggtggcg cttggtacaa atgccgtgcg agtagctgcg
     2941 gcctctgcgg gcgggattgt cggcagttta tctcaatcac aacttggtga tctgggcgag
     3001 aaattagtca attcgcaatt ctcccagcgc caggaagcag aagccgatga ttattcttac
     3061 gatcttctac gccaacgcgg catcagcccg gcaggtcttg ccaccagctt tgaaaaactg
     3121 gcgaaactgg aagaaggccg ccaaagctca atgtttgacg accatccggc atccgccgaa
     3181 cgcgcccagc atattcgcga tcgcatgagc gcggatggga taaagtgatt tcatatttct
     3241 ctgacaggaa tgtcggagaa attttcattc agagccggcc agagtcatta aacaagctca
     3301 atcatttggg gcatcaattc gcttcgtaga ttgctttatc tggtgtatcc ggttgcacct
     3361 ctactacatc ggcagtgctt acgccacaag cccaggcaaa agccgtctct gttccttcag
     3421 gtaatggagt atcccagggt aaagtacgcc acggactccc ctgctctttt aataaagatg
     3481 taatggcttt cttaaaaaga atatgggtaa tcaggtgccg tttatccgtt gctttccagt
     3541 accaacgggc cagcaaaaaa tgcccggcca attcgcgcca gcttctgtaa tgttgctgta
     3601 cgcgtctggc tgccagcatc gaaaaatcga ccatttcacg ctgggtaatg tatcccactt
     3661 gcgccccgct attacatagc atgacaaaac gcaccatatc ccaggcacaa aaatctatat
     3721 cgcatatttt acgtcgattt tttctgacca tctgtagctg ccacaaacgc tctttcgctt
     3781 cgctacttga tttcgcgttc tgagctaatt gctgagcgaa cgcgcgatac tcagcatccg
     3841 gcatttcgct atcgtttttg atctgttctg cataaactga acggtgccct gctacaaaca
     3901 aagctaagag ttgctcaagt aacgaatccc gatcaaagac gccccacatg tcagcaagtg
     3961 actcaacttc acttttgcaa tcattctctg cttccacgga atcatcatta acgactcgtc
     4021 gcgcccagtg attgttaccc gcaatggcat aaggcgcgcc gactgccatt gcccaacgtt
     4081 cggcagcagg aattttttga attgagggat ctttacagga tgctttgaaa aggcgatgtc
     4141 cggcgaacac caggccataa ccaatccaca aaacagccac caaggcgaga ataagtatta
     4201 tcgctaccag ataaagggca tatttgccta ttgtcagtaa gacatccagc caggaagagt
     4261 ctggctccgt aactgtttgc tccaccgatg tcaaagggga attactgacc cgctctggcg
     4321 cggtcctcgt caacagaggg aaatccctat gttgcttgaa tgagcgtttt ttaagcaaat
     4381 ctattttttt ctgcacctca tcagtaaccc gaccgttttt ttcaaactca tgtaacgatg
     4441 caaaatcaat cgccgcaatc ttccatttac catccccttc acggattaat tccattggaa
     4501 tatcaatata agattggtga ccaaaaaaag caccaatctg cgccttgtcg ccttcgacga
     4561 aggtcgctaa aggatcgcta taactgggga aacgtcgttt acacgttttg ggtgactctt
     4621 gccagtattt cagtacaggc tccattaaag caggcgtaaa tacttgctgc atttccgcaa
     4681 ggcgatcgtg cgaatctgtg ctggtgacaa actcagggcc acataatgcg cgataactct
     4741 ttttgacgac agaggaaata gcttctttgt cttgttgcag ctgtgcggca attttctgtt
     4801 tttctgctct atcgcagcca gttgataaaa gaaataacaa acaaagaaga ggcttccagg
     4861 gaagagtgcg ttccatctat ttattccatt aaaaacacgg taataacaat ccattaaaaa
     4921 aacagcagtc agggtaaaga tgacttaatt aacaggatag gttttaaatg ataagtccct
     4981 tgtgccagac aagggactgt gcaaaaaatt cgaccaggca ggttacttac tcgccctttt
     5041 tcgccgcctg aatatacagc atttccagcg ccagcgttgc cgctgccaga gcagtgattt
     5101 ccgactgatc gtatgccgga gccacttcca ctacgtccat cccaacgatg ttgagatctt
     5161 tcaggccgcg taccagttta atggcgcgat cggaggtcag gccgccaatc actggcgtac
     5221 cggttcccgg cgcgaaagca ggatccaggc agtcgatatc aaaggtcagg taaaccggca
     5281 tatcacccac aatctgtttc acttgggcga taacgtcatc cacgctgcga tcgttcacct
     5341 ggcaggcgtc cagcacggta aaaccgttgt ctttatcaaa ctcggtacga ataccaatct
     5401 gcacggaatg attcgggtcg atcagacctt ctttcggcgc ggtatagaac atggtgccgt
     5461 ggtcaaattc acaaccgttc gcgtaggtat cggtgtgggc gtcaaagtgt accagcgcca
     5521 ttttgccgaa atgcttcgca tgagcacgca gcagcggcag cgtaacaaag tggtcaccac
     5581 cgaaagagag catacgctta ccggcagcca gcagcttctc ggcgtgtgcc tgcagttttt
     5641 cgctcatctc acgggcatcg ccaaaggcat ataccagatc gccgcagtcc acgacgttca
     5701 ggcgctcacg catgtcgaaa ttccacggga agcgattgtg ttcccaggca agattcgtcg
     5761 aaacctgacg gatcgctgcc ggaccgtggc gtccccccgc acgaccagaa gtggccatat
     5821 cgaacggcac accagtaatc acccagtcag catcgctgtc atacggctgg aagttcatcg
     5881 gcaggcgtaa aaaaccaaag gcgttggaaa ccagtgagtt atcgtattga tgacctaagg
     5941 tgctcatgga tggactccta ttacaaagtc gatataaaaa aacccttccg cgtcgttagg
     6001 cccgacgagg aagggttgga tttgtcacaa taaattgtgg cggattatca ccgctaaatt
     6061 aagcggattc aagtaatacg gacttactca tcttccagat aagtataacc gtacaaacct
     6121 gcctcgaact cttcaaggaa ctgttgttgc agttcagcat caagatcggt tttcttcact
     6181 tgatcgcgga actgagttaa cagcgttttc ggatcgagct gcacatattg cagcatatcc
     6241 gcaacggtat cgccttcgtc agacagttcc acttctacac taccgtcagg gaagacgaac
     6301 acgtcaaccg cttcggtatc accgaacagg ttgtgcatgt tgccgaggat ctcctgatat
     6361 gcgccgacca taaagaaacc gagcatcggc ggattctctg gatcgtactc cggcattggc
     6421 attgtcgtgg caataccatc accatcaata tagtggtcga tagcaccgtc agagtcacag
     6481 gtaatatcca gcagcacagc gcgacgttcc ggcacttgat ccagcccttc cagcggcaga
     6541 accgggaaca actggtcgat cccccatgcg tccggcattg actggaacag cgagaaattg
     6601 acgtacattt tgtccgccat acgttcctgc agttcgtcga ttatcggacg atgcgcacgg
     6661 ttttgcggat ccagttgctt ctgcacttca tggcacatgc tcagatagag ttgttctgcc
     6721 catgcacgtt cttgcaggct aaaggtgccg gaagagtagc cgatatgaat gtcgtgcaga
     6781 tccatctgac tgtcgtgtaa ccattcacgc agagaacggc gagttcccgg ttcgtgcatc
     6841 tcctgccagg tttcccacat gctttgcagc gcgcgcggcg catcttctgc aggcgcggtc
     6901 ggcaccgtgt attcgttacg ttccacgccg atgatattag acaccagcac ggtgtgatgc
     6961 gcagtcaccg cacgacccga ttcggtgatt accgtcggat gcggcagacc gttttcttca
     7021 cacgcatcac caatcgccca gatgatgttg ttggcatatt cattgaggcc gtagtttacg
     7081 gagcagtcag actgcgaacg ggtgccttca tagtccacgc ccagaccgcc gccgacgtcg
     7141 aagcactgaa tattgacgcc cagcttgtgc agttccacat agaaacgcgc cgattcacga
     7201 acgcctgtgg cgatatcgcg aatattcgcc atctgcgaac cgaggtggaa gtgcagtagt
     7261 tgcaggctgt cgagacgccc ggcttcacgc agggtttcaa ccagttgcag tacctgagtc
     7321 gcagccaggc cgaacttcga tttttccccg ccggaggact gccatttacc cgagccctgc
     7381 gaagccagac gtgcacgcac gcccagacga ggaacgacat tcagacgttc tgcttcatcc
     7441 agcacaatgg cgatttctga catcttctca atgaccagat agaccttgtg ccccatcttc
     7501 tcgccaatta atgccaggcg gatatattcg cggtctttat aaccgttgca gacgatgacg
     7561 ctacgggtca tgccagcatg tgccagcact gccatcaatt cggctttgga accggcttcc
     7621 agacccagcg gttcgcccga atgaattagg gactcaatca cgcgacggtg ctggttaact
     7681 ttgatcggat aaacaaggaa gtaatcgccg ttatagccgt aggattccct cgcacgtttg
     7741 aacgcggcgt taatggaacg caaacggtgc tgcaggatct gtgggaaaca gaacagtgca
     7801 ggcagacgct gaccctgtgc ttcacgagtt ttcactaact gcgcgagatc gacgcgagct
     7861 tccgggacgt ccgggtccgg gcacacgctg atgtggccca gctcgttaac gtcatagtag
     7921 ttattgcccc accaggcaat attgtaagta cgcagcatct tgctggcttc ctgggagctc
     7981 attgcaacct cctgcatgga gcgtagtaca ccgtgttcgc ccgctgacga aggcaaaccc
     8041 atagacatgt cgtcagacat agcgaacctc aaattatttt attaagtgta aaacagttaa
     8101 cgactatcgc agcctggaac tgcgataaca acccataagc acatggattt tccagcagtg
     8161 aatgctgacg ctccaactgc gcaaccggtt tctttttcat aacattatta agcacataac
     8221 cgaacgtaag tgtgacagtt cggcgaaacc acgagaaaac tcttgttttt acaagagcgc
     8281 ccttgttcag tcctcagtaa ctgtaaccag ctcttgaatc ctgagaagcg ccgagatggg
     8341 tataacatcg gcaggtatgc aaagcagaga tgcagagtgc ggggaacgaa tcttcaccag
     8401 aacggtgaga caggttaagc agcagacaac ggttcattat ttcgtatcac ctccacggcc
     8461 gcctgttaag acgaacccac aagccaaaac tctgatttca acccggctgg aagtggcaac
     8521 acgaaagaaa cgtcgtgtgc tttttattta agccgcgcgc cgcgttttat accccacaat
     8581 ggcagaaaat tgcaaaagat aaatacgcag aatgccggca ttgtcaggaa aaatttccag
     8641 ccacgttttt aacagaatga gacacgattc aaaaaaaagt ggaaatcggg tgaagaattg
     8701 acctaaaata gccatccaga tgttaatcca tccataccga ttaacactca gactgccagt
     8761 gtttttaact tgcagagtcg tggtaggatc cgctaccaca gaaaatccac acaacagttt
     8821 gagctaacca aattctcttt aggtgatatt aaatatggca aaacaccttt ttacgtccga
     8881 gtccgtctct gaagggcatc ctgacaaaat tgctgaccaa atctctgatg ccgttttaga
     8941 cgcgatcctc gaacaggatc cgaaagcacg cgttgcttgc gaaacctacg taaaaaccgg
     9001 catggtttta gttggcggcg aaatcaccac cagcgcctgg gtagacatcg aagagatcac
     9061 ccgtaacacc gttcgcgaaa ttggctatgt gcattccgac atgggctttg acgctaactc
     9121 ctgtgcggtt ctgagcgcta tcggcaaaca gtctcctgac atcaaccagg gcgttgaccg
     9181 tgccgatccg ctggaacagg gcgcgggtga ccagggtctg atgtttggct acgcaactaa
     9241 tgaaaccgac gtgctgatgc cagcacctat cacctatgca caccgtctgg tacagcgtca
     9301 ggctgaagtg cgtaaaaacg gcactctgcc gtggctgcgc ccggacgcga aaagccaggt
     9361 gactttccag tatgacgacg gcaaaatcgt tggtattgat gctgtcgtgc tttccactca
     9421 gcactctgaa gagatcgacc agaaatcgct gcaagaagcg gtaatggaag agatcatcaa
     9481 gccaattctg cccgctgaat ggctgacttc tgccaccaaa ttcttcatca acccgaccgg
     9541 tcgttttgtt atcggtggcc cgatgggtga ctgcggtctg actggtcgta aaattatcgt
     9601 tgatacctac ggcggcatgg cacgtcacgg tggcggagca ttctctggta aagatccatc
     9661 aaaagtggac cgttccgcag cctacgcagc acgttatgtc gcgaaaaaca tcgttgctgc
     9721 tggcctggcc gatcgttgtg aaattcaggt ttcctacgca atcggcgtgg ctgaaccgac
     9781 ctccatcatg gtagaaactt tcggtactga gaaagtgcct tctgaacaac tgactctgct
     9841 ggtacgtgag ttcttcgacc tgcgcccata cggtctgatt cagatgctgg atctgctgca
     9901 cccgatctac aaagaaaccg cagcatacgg tcactttggt cgtgaacatt tcccgtggga
     9961 aaaaaccgac aaagcgcagc tgctgcgcga tgctgccggt ctgaagtaat ctttcttcac
    10021 ctgctttcaa aggccagcct cgcgctggcc tttttctttt acctcaccgc ggtggatagg
    10081 cattcacgcc gcatccggca aaaagctgcc cgcacaataa catcattctt cctcaacacg
    10141 ttttatcgca aattatcatc actactgaaa ccgattacac caataacacc agccaaatat
    10201 ttgtaatatt ttcatattat tattcagttt tcacagttgt tacatttctt ttcagtaaag
    10261 tcttaattgc agataacagc gtttaatcta tgatgatata actcaattat tttcatgcac
    10321 ttaaaccata actaagataa atgttagtgt aagcgattac actgatgtga tttgcttcac
    10381 atctttttac gtcgtactca cctatcttaa ttcacaataa aaaataacca tattggaggg
    10441 catcatgcct gacgctaaaa aacaggggcg gtcaaacaag gcaatgacgt ttttcgtctg
    10501 cttccttgcc gctctggcgg gattactctt tggcctggat atcggtgtaa ttgctggcgc
    10561 actgccgttt attgcagatg aattccagat tacttcgcac acgcaagaat gggtcgtaag
    10621 ctccatgatg ttcggtgcgg cagtcggtgc ggtgggcagc ggctggctct cctttaaact
    10681 cgggcgcaaa aagagcctga tgatcggcgc aattttgttt gttgccggtt cgctgttctc
    10741 tgcggctgcg ccaaacgttg aagtactgat tctttcccgc gttctactgg ggctggcggt
    10801 gggtgtggcc tcttataccg caccgctgta cctctctgaa attgcgccgg aaaaaattcg
    10861 tggcagtatg atctcgatgt atcagttgat gatcactatc gggatcctcg gtgcttatct
    10921 ttctgatacc gccttcagct acaccggtgc atggcgctgg atgctgggtg tgattatcat
    10981 cccggcaatt ttgctgctga ttggtgtctt cttcctgcca gacagcccac gttggtttgc
    11041 cgccaaacgc cgttttgttg atgccgaacg cgtgctgcta cgcctgcgtg acaccagcgc
    11101 ggaagcgaaa cgcgaactgg atgaaatccg tgaaagtttg caggttaaac agagtggctg
    11161 ggcgctgttt aaagagaaca gcaacttccg ccgcgcggtg ttccttggcg tactgttgca
    11221 ggtaatgcag caattcaccg ggatgaacgt catcatgtat tacgcgccga aaatcttcga
    11281 actggcgggt tataccaaca ctaccgagca aatgtggggg accgtgattg tcggcctgac
    11341 caacgtactt gccaccttta tcgcaatcgg ccttgttgac cgctggggac gtaaaccaac
    11401 gctaacgctg ggcttcctgg tgatggctgc tggcatgggc gtactcggta caatgatgca
    11461 tatcggtatt cactctccgt cggcgcagta tttcgccatc gccatgctgc tgatgtttat
    11521 tgtcggtttt gccatgagtg ccggtccgct gatttgggta ctgtgctccg aaattcagcc
    11581 gctgaaaggc cgcgattttg gcatcacctg ctccactgcc accaactgga ttgccaacat
    11641 gatcgttggc gcaacgttcc tgaccatgct caacacgctg ggtaacgcca acaccttctg
    11701 ggtgtatgcg gctctgaacg tactgtttat cctgctgaca ttgtggctgg taccggaaac
    11761 caaacacgtt tcgctggaac atattgaacg taatctgatg aaaggtcgta aactgcgcga
    11821 aatcggcgct cacgattaat ctcctcaggc ttcctcccgt cgcggaggaa gccacctctt
    11881 gcagtcatct tttctttgct ctatcctctg ccgctatgaa aacatcccgt ctccctatcg
    11941 ccatccaaca ggccgttatg cgtcgcctgc gggaaaaact cgcccaagcc aacctgaagc
    12001 tagggcgtaa ctacccggag ccaaaactct cttacaccca gcgcggaacc tccgccggaa
    12061 cggcctggct ggaaagctat gaaattcgcc tcaatcccgt tttgctgttg gaaaacagtg
    12121 aagcttttat tgaagaagtg gtaccgcacg aactggcaca tttgctggta tggaaacatt
    12181 tcggccgcgt agcgccacat ggcaaagagt ggaagtggat gatggaaagc gtgctgggtg
    12241 ttcccgcccg tcgtacgcat cagttcgaac tgcaatccgt gcgtcgcaac accttcccct
    12301 accgctgcaa gtgccaggag catcagctta ccgtacgccg ccataatcgc gtagttcgtg
    12361 gcgaggccgt ctatcgctgt gttcactgcg gtgaacagct ggttgcgaaa taaccatctg
    12421 aactatcagg aactttcctg atctggctga ttgcatacca aaacaacttt cgctacgttg
    12481 ctggctcgtt ttaacacgga gtaagtgatg taccgttatt tgtctattgc tgcggtggta
    12541 ctgagcgcag cattttccgg cccggctttg gccgaaagta tcaatagttt ttctcaggcg
    12601 aaagccgcgg cggtaaaagt ccacgctgac gcgcccggta cgttttattg cggatgtaaa
    12661 attaactggc agggcaaaaa aggcgttgtt gatctgcaat cgtgcggcta tcaggtgcgc
    12721 aaaaatgaaa accgcgccag ccgcgtagag tgggaacacg tcgttcccgc ctggcagttc
    12781 ggtcaccagc gccagtgctg gcaggacggt ggacgtaaaa actgcgctaa agatccggtc
    12841 tatcgcaaga tggaaagcga tatgcataac ctgcaaccgt cagtcggcga ggtgaatggc
    12901 gatcgcggca actttatgta cagccagtgg aatggcggcg aaggccagta cggtcaatgc
    12961 gccatgaagg tcgatttcaa agaaaaagct gccgaaccac cagcgcgtgc acgcggtgcc
    13021 attgcgcgca cctacttcta tatgcgcgac caatacaacc tgacactctc tcgccagcaa
    13081 acgcagctgt tcaacgcatg gaacaagatg tatccggtta ccgactggga gtgcgagcgc
    13141 gatgaacgca tcgcgaaggt gcagggcaat cataacccgt atgtgcaacg cgcttgccag
    13201 gcgcgaaaga gctaacctac actagcggga ttctttttgt taacccctac cccacgcgta
    13261 caaccgcgtg gggagacgac gcggattttt aactatgcgt atcccccgca tttatcatcc
    13321 tgaaccactg accagccatt ctcacatcgc gctttgcgaa gatgccgcca accatatcgg
    13381 gcgcgtactg cgcatggggc cggggcaggc gttgcaattg tttgacggta gcaaccaggt
    13441 ctttgacgcc gaaattacca gcgccagcaa aaaaagcgtg gaagtgaagg tgctggaagg
    13501 caagatcgac gatcgcgaat ctccgctgca tattcacctc ggtcaggtga tgtcgcgtgg
    13561 tgaaaaaatg gaatttacga tccagaaatc gatcgaactc ggtgtaagcc tcattacgcc
    13621 acttttttct gagcgctgcg gcgttaaact ggatagtgaa cgtctgaaca agaagcttca
    13681 gcagtggcag aagattgcaa ttgctgcctg tgagcagtgt ggtcgtaacc gggtgccgga
    13741 aatccgtcca gcgatggatc tggaagcctg gtgtgcagag caggatgaag gactgaaact
    13801 gaatcttcac ccgcgcgcca gtaacagcat caatacgttg cctttaccgg ttgaacgcgt
    13861 ccgcctgctg attggcccgg aaggcggttt atcggcagat gaaattgcca tgactgcccg
    13921 ctatcaattt actgatatcc tgttgggacc tcgcgttttg cgtacagaga caactgcgct
    13981 caccgccatt accgcgctac aagtacgatt tggcgatttg ggctaacgga gaagaataat
    14041 gatcaagctc ggcatcgtga tggaccccat cgcaaacatc aacatcaaga aagattccag
    14101 tttcgctatg ttgctggaag cacagcgtcg tggttacgaa cttcactata tggagatggg
    14161 cgatctgtat ctgatcaatg gcgaagcccg cgcccatacc cgcacgctga acgtgaagca
    14221 gaactacgaa gagtggtttt cattcgtcgg tgaacaggat ctgccgctgg ccgatctcga
    14281 tgtgatcctg atgcgtaaag acccgccgtt tgataccgag tttatctacg cgacctatat
    14341 tctggaacgt gccgaagaga aagggacgct gatcgttaac aagccgcaga gcctgcgcga
    14401 ctgtaacgag aaactgttta ccgcctggtt ctctgactta acgccagaaa cgctggttac
    14461 gcgcaataaa gcgcagctaa aagcgttctg ggagaaacac agcgacatca ttcttaagcc
    14521 gctggacggt atgggcggcg cgtcgatttt ccgcgtgaaa gaaggcgatc caaacctcgg
    14581 cgtgattgcc gaaaccctga ctgagcatgg cactcgctac tgcatggcgc aaaattacct
    14641 gccagccatt aaagatggcg acaaacgcgt gctggtggtg gatggcgagc cggtaccgta
    14701 ctgcctggcg cgtattcctc aggggggcga aacccgtggc aatctggctg ccggtggtcg
    14761 cggtgaacct cgtccgctga cggaaagtga ctggaaaatc gcccgtcaga tcgggccgac
    14821 gctgaaagaa aaagggctga tttttgttgg tctggatatc atcggcgacc gtctgactga
    14881 aattaacgtc accagcccaa cctgtattcg tgagattgaa gcagagtttc cggtgtcgat
    14941 caccggaatg ttaatggatg ccatcgaagc acgtttacag cagcagtaac ccaccttagc
    15001 gagaaggatc tcgttgagac tctgagtgac agcgcccttc tttccacgca tactgggcgc
    15061 tgttgctttt ttgaaccagg aaacagaacc tctgacaatg aatttacagc atcactttct
    15121 tattgccatg cctgctctcc aggatccgat tttccgtcgt tccgtggtct acatttgcga
    15181 acataatacc aatggtgcaa tggggatcat cgtcaacaag ccgctggaaa atctcaaaat
    15241 tgaagggatt ctggaaaagc tgaagatcac gccggagccg cgtgatgaat caatccgtct
    15301 ggataaaccg gttatgctcg gcggtccgct ggctgaagat cgcgggttta ttttgcatac
    15361 tccgccctcc aattttgctt ccagcattcg catttcagac aacacagtga tgaccacttc
    15421 ccgcgatgtg ctggaaacgc tcggcaccga taaacaaccg tctgacgtat tggtggctct
    15481 gggttatgcc tcctgggaaa aaggtcaact ggaacaagaa attctcgata acgcgtggct
    15541 aacggccccg gcggatctga atattctgtt caaaacaccg attgccgacc gctggcgcga
    15601 ggcggcaaaa ctgattggtg tggatattct caccatgcct ggtgtggcag ggcacgcctg
    15661 atgagtggaa ccttactcgc cttcgacttc ggcaccaaaa gcattggcgt agcggtcggc
    15721 caacgcatta ccggcactgc tcgccctttg cctgcaatta aagcacagga cggtacgccg
    15781 gactggaacc tcatcgaacg tttactgaaa gagtggcagc cggacgaaat catcgtcggt
    15841 ttgccgctga atatggacgg caccgagcaa ccattgactg ccagagcgcg taaatttgcc
    15901 aaccgtattc atggtcgttt cggtgttgaa gtaaagctcc atgacgaacg tcttagcacc
    15961 gtggaagccc gttccggtct gtttgaacag ggcggctatc gggcgctcaa caaaggcaaa
    16021 gttgactctg cctctgcggt tattattctc gaaagctatt tcgagcaggg atattaaggc
    16081 gatttaaacg cctgctggag tgtataatat catcgcgcct tacgccttat tgccggatgc
    16141 ggcgtgaacg ccttatccgg cctacatgtg gcagcgattg taggtctgat aagacgcgtt
    16201 agcgtcgcat cagacattta ttgcctttat aggccctata aacttgcgca tcgggcatgg
    16261 caacgtcaca aacgcccttc ccccacccgc tgctgataac tctgctgaaa cgttatcatc
    16321 cccacctgct gcccggtttg aataacatgc ggtaactggt gggttttccc ttcgcgaatc
    16381 aaattcccca ccgcgggagt gttaatcaat aattcaaaca gcgccacgcg tccttcctgt
    16441 ttatccactt ccagcttttg tgacaacacg gcccgtaaac tacctgccag ttgattacgt
    16501 acgggatctt tttcctgcgc cggaaatgaa tccaccagtc gctcaactgc ctgcgcggca
    16561 ccacgcgtat gtaatgttgc cagcaccaaa tgcccggttt ctgccgccgt cagtgccaga
    16621 cggattgtct cgctgtcacg cagctctccg agcaaaatca catcaggatc ttcccgcaat
    16681 gcggcccgca atcccgatgc gaacgtcata cagtgcaaac caatttcccg ctgctggatc
    16741 aaacatcgct ggctggcata gatatattca acaggatctt ccagcgtcag aatatgcgca
    16801 tcggcatgtt gattgagata gccaaccatc gccgccagcg tggtagattt gccgctcccc
    16861 gtcgcccccg tcaccagaat caggccattc tcgctcttga gtaattccgg caataccgtt
    16921 ggtgcgccaa gctgttcgag ctgtggacag tgcgaaggta acaaccgtaa tgccagagaa
    16981 ataccttgcc gttgcgcgaa cgcactgcca cgcaaccgct ggttttccgc cagcgacacg
    17041 gcaaaatcca gctggccatt ttccagcaat attgcccgct gatcgtcatc cagccactcc
    17101 cgcagtagct cttcgacgtc cggcgcatca aacggcgcag cttccattct gccacgaatg
    17161 cgccatcgtg cgggccaggc gctgcacagg tgtagatccg agacgttatg ctttacacta
    17221 agggccacaa tttcttccat attcatacta agatcctcgg aaaatgaacg atattgcgca
    17281 taacctggca caggtccggg acaaaatctc agcggctgca acgcgttgcg gccgttctcc
    17341 agaagaaatt acgctgcttg cagtcagtaa aacaaaacct gcgagcgcca tcgcagaagc
    17401 cattgatgcc gggcagcgtc aatttggtga aaactacgtt caggaagggg tagataaaat
    17461 tcgccacttt caggaactgg gcgtaacagg attagaatgg cattttattg gcccgttgca
    17521 gtctaataaa agccgcctgg tggcagagca tttcgactgg tgtcatacca tcgaccgttt
    17581 gcgcattgct acccgcctca acgatcagcg cccggcagaa cttccccctc ttaacgtact
    17641 gattcaaatt aatattagtg atgaaaacag taagtccggg attcaactgg cagaactgga
    17701 cgagctggca gcggcggtcg ctgaactacc gcgtttacgt ctgcgcgggc tgatggcaat
    17761 ccctgcgcct gagtcagaat atgtaaggca gtttgaagtt gcacgccaaa tggctgtagc
    17821 atttgccgga ctgaaaacgc gctacccgca tatcgacacg ctctctctgg gaatgtcgga
    17881 cgatatggaa gccgccattg cggcaggtag cacgatggtt cgtatcggca ctgcaatttt
    17941 tggtgcgcgt gattactcta aaaaataagg aattaaagga acgccatgaa tacgttgact
    18001 ttcctgcttt caacggtcat tgagctgtat accatggtgc tgttattacg catctggatg
    18061 cagtgggctc attgtgattt ttacaacccc ttctcacagt ttgtagtgaa ggtaacacag
    18121 ccaattatcg ggccactgcg ccgcgttatt ccggcaatgg gtcccattga tagcgcctcg
    18181 ctgctggttg cgtacattct cagttttatc aaagccatcg tgctgtttaa agtggtgacc
    18241 ttcctgccaa tcatctggat tgccggttta ctgattctgc tgaaaaccat cggcctgctg
    18301 attttctggg tcctgctggt gatggcgatt atgagctggg taagccaggg tcgtagtccg
    18361 attgaatacg tgctgattca gctggccgat ccgctgctgc gcccgattcg ccgcctgcta
    18421 ccggcaatgg gtgggattga tttctcgccg atgatcctcg ttctgctgct gtatgtcatc
    18481 aatatgggtg tcgcagaagt attacaggca accggaaaca tgctgctgcc ggggctgtgg
    18541 atggcgttat gagtgccgta acagttaatg atgacggtct ggttttacgg ctctatattc
    18601 agccgaaagc cagccgtgat tctattgtcg gtttacatgg cgacgaagtt aaagtcgcca
    18661 ttaccgcgcc gccggttgac ggccaggcca acagccatct ggtgaagttt ctcggtaagc
    18721 aattccgggt agccaaaagc caggtggtaa ttgaaaaagg cgaacttggc cgccacaaac
    18781 aaattaaaat cattaatccg caacaaatcc cgccagaaat cgcggcgtta attaattagg
    18841 tatcctatgc aaaaagttgt cctcgcaacc ggcaatgccg gtaaagtgcg tgagctggcg
    18901 tcgctgctta gcgacttcgg tcttgatatc gtggcccaaa cagacctcgg cgtagattcc
    18961 gctgaagaaa ccggcctgac ctttatcgaa aacgcgattc tgaaagcgcg ccatgcggca
    19021 aaagtgaccg gtttaccggc aattgccgac gactctggtc tggcggtaga tgcgctgggt
    19081 ggcgcgccgg gtatttactc cgcgcgttat tccggtgaag acgcgaccga tcaaaagaat
    19141 ctgcaaaaac tgttggaaac actgaaagac gtaccggacg accaacgtca ggcgcgtttc
    19201 cactgcgtgc tggtatatct gcgtcacgcg gaagatccga ctccgctggt gtgccacggt
    19261 agctggccgg gcgtgattac tcgtgaacca gcgggcactg gtggctttgg ttatgatcca
    19321 atcttcttcg taccttccga agggaaaacc gctgccgaac tgacccgcga agaaaagagc
    19381 gccatttccc accgtggtca ggcattgaaa ctgctgttgg acgctttacg taatggttaa
    19441 attaccgccg ctgagtctct acattcacat cccgtggtgc gtgcagaaat gcccgtactg
    19501 cgatttcaac tctcacgcgt tgaaaggaga agtgccgcac gacgattacg ttcagcatct
    19561 gctttgcgat ctggacaacg atgtggctta cgctcagggc cgtgaagtaa agacaatctt
    19621 tattggcggt ggtacgccga gcctgctttc cggcccggcg atgcaaacgc tgctggacgg
    19681 cgtgcgtgcg cgtttgccgc tggcagcgga tgcagaaatt actatggaag cgaaccctgg
    19741 tacggtagaa gccgatcgct ttgtcgatta tcagcgtgct ggtgtgaacc gcatctctat
    19801 tggtgtgcag agttttagcg aagacaagct gaaacgactt gggcgtattc atggcccgca
    19861 agaagcgaaa cgcgcggcaa agctggcgag cgggctgggg ctgcgtagct ttaacctcga
    19921 tttgatgcat ggactaccgg atcaatcact ggaagaggcg cttggcgatc tacgccaggc
    19981 cattgaactg aatccgccgc atctttcctg gtatcaactg accatcgaac ctaatacgct
    20041 gtttggttca cgcccgccgg tactgccgga cgacgacgcg ctgtgggata tattcgaaca
    20101 ggggcatcag ttattaaccg cagcgggtta tcagcaatat gaaacttccg cttacgccaa
    20161 acccagttat cagtgccagc acaatctcaa ctactggcgc tttggcgact acatcggtat
    20221 tggctgcggc gcgcacggca aagtgacctt cccggatggg cgcattctgc gtaccactaa
    20281 aacgcgtcat ccgcgtggtt ttatgcaagg aaggtatctg gaaagccagc gtgatgtcga
    20341 agccgcagat aagccgtttg agttctttat gaatcgcttc cgtctgctgg aggccgcgcc
    20401 gcgcgtggag tttattgcgt ataccgggct ttgcgaagat gtgattcgcc cacagttaga
    20461 cgaggcgatt gcccagggtt atctcaccga atgtgcggat tactggcaga taacggaaca
    20521 tggtaaatta ttcttaaact cacttcttga attattcctc gctgagtaat cattaatgcg
    20581 tctgcgggcg catt
//
LOCUS       DAZUDJ010000078        19920 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.078, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000078 DAZUDJ010000000
VERSION     DAZUDJ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19920
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.078"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..166
                     /locus_tag="ACHY1N_004012"
     CDS             <1..166
                     /locus_tag="ACHY1N_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046222.1"
                     /translation="SEELLPDNTLEKDENSPDNGFEVGEYNTYEAYNSENQYFTREDY
                     TYNYDLLNAI"
     gene            complement(674..1050)
                     /gene="rnpB"
                     /locus_tag="ACHY1N_004013"
     ncRNA           complement(674..1050)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACHY1N_004013"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(1083..2228)
                     /gene="garK"
                     /locus_tag="ACHY1N_004014"
     CDS             complement(1083..2228)
                     /gene="garK"
                     /locus_tag="ACHY1N_004014"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312029.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HFS4046223.1"
                     /translation="MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSIPVADG
                     GEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAE
                     KRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
                     IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAM
                     IVELDNNLSHYAEVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTAL
                     NLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVIGIAGSLTDDVGVVH
                     QHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG"
     gene            complement(2325..3215)
                     /gene="garR"
                     /locus_tag="ACHY1N_004015"
     CDS             complement(2325..3215)
                     /gene="garR"
                     /locus_tag="ACHY1N_004015"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008679 - 2-hydroxy-3-oxopropionate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0046487 - glyoxylate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HFS4046224.1"
                     /translation="MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAA
                     GAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGT
                     ADHSALACYYEKLAKVEVTR"
     gene            complement(3245..4015)
                     /gene="garL"
                     /locus_tag="ACHY1N_004016"
     CDS             complement(3245..4015)
                     /gene="garL"
                     /locus_tag="ACHY1N_004016"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008672 - 2-dehydro-3-deoxyglucarate
                     aldolase activity [Evidence IEA];
                     GO_process: GO:0019394 - glucarate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HFS4046225.1"
                     /translation="MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWL
                     VLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVET
                     KEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAP
                     VEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK"
     gene            complement(4031..5365)
                     /gene="garP"
                     /locus_tag="ACHY1N_004017"
     CDS             complement(4031..5365)
                     /gene="garP"
                     /locus_tag="ACHY1N_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GarP"
                     /protein_id="HFS4046226.1"
                     /translation="MILDTVDEKKKDVHTRYLILLIIFIVTAVNYADRATLSIAGTEV
                     AKELQLSAVSMGYIFSAFGWAHLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGF
                     VDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
                     LALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISE
                     NGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIY
                     LVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLL
                     ASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGN
                     VASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK"
     gene            5740..7311
                     /gene="garD"
                     /locus_tag="ACHY1N_004018"
     CDS             5740..7311
                     /gene="garD"
                     /locus_tag="ACHY1N_004018"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008867 - galactarate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0046392 - galactarate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HFS4046227.1"
                     /translation="MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLE
                     LIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTL
                     PLATKVPAPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL
                     LPKYPNVDGVVGLNHLYGCGMAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKL
                     QPERLLVGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQVAERHLQKLNQRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW
                     GLHNQLAVFNPAPVT"
     gene            7460..7795
                     /gene="prlF"
                     /locus_tag="ACHY1N_004019"
     CDS             7460..7795
                     /gene="prlF"
                     /locus_tag="ACHY1N_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PrlF"
                     /protein_id="HFS4046228.1"
                     /translation="MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHY
                     EILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVN
                     IDDEIGDDE"
     gene            7795..8259
                     /gene="yhaV"
                     /locus_tag="ACHY1N_004020"
     CDS             7795..8259
                     /gene="yhaV"
                     /locus_tag="ACHY1N_004020"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ribonuclease
                     toxin YhaV"
                     /protein_id="HFS4046229.1"
                     /translation="MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKA
                     ATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRLFFRYSEK
                     EKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWESLTQETEENH"
     gene            complement(8314..9123)
                     /gene="agaR"
                     /locus_tag="ACHY1N_004021"
     CDS             complement(8314..9123)
                     /gene="agaR"
                     /locus_tag="ACHY1N_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aga operon transcriptional regulator AgaR"
                     /protein_id="HFS4046230.1"
                     /translation="MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVS
                     TVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVE
                     LIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
                     RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERII
                     VVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE"
     gene            9372..10652
                     /gene="kbaZ"
                     /locus_tag="ACHY1N_004022"
     CDS             9372..10652
                     /gene="kbaZ"
                     /locus_tag="ACHY1N_004022"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaZ"
                     /protein_id="HFS4046231.1"
                     /translation="MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYTSANQTPL
                     LIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPA
                     AQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCL
                     EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARAMLEAHRHAFEKQGLNAIWP
                     RIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLV
                     IDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLEDVMLDRPEYWQSH
                     YHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQY
                     VKVRSGELQPTPRELIINHIQDILAQYHTACEGQ"
     gene            10675..11148
                     /gene="agaV"
                     /locus_tag="ACHY1N_004023"
     CDS             10675..11148
                     /gene="agaV"
                     /locus_tag="ACHY1N_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312038.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HFS4046232.1"
                     /translation="MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQ
                     QNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRI
                     NVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKAAGVECFVQGVPTEPAVDLFKLL"
     gene            11159..11938
                     /gene="agaW"
                     /locus_tag="ACHY1N_004024"
     CDS             11159..11938
                     /gene="agaW"
                     /locus_tag="ACHY1N_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIC"
                     /protein_id="HFS4046233.1"
                     /translation="MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLG
                     DLHTGILTGGTLELVWMGLAPLAGAQPPNVIIGTIVGTAFAITTGVKPDVAVGVAVPF
                     AVAVQMGITFLFSVMSGVMSRCDRMAENADTRGIERVNYLALLALGTFYFLCAFLPIY
                     FGAEHAKTIIDVLPQRLIDGLGVAGGIMPAIGFAVLLKIMMKNVYIPYFILGFVAAAW
                     LKLPVLAIAAAALAMALIDLLRKSPEPTQPAAQKEEFEDGI"
     gene            11928..12806
                     /gene="agaE"
                     /locus_tag="ACHY1N_004025"
     CDS             11928..12806
                     /gene="agaE"
                     /locus_tag="ACHY1N_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019079236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IID"
                     /protein_id="HFS4046234.1"
                     /translation="MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRV
                     AWRSMLLQASFNYERMQASGWLYGLLPALKKIHTNKRDLARAMKGHMGFFNTHPFLVT
                     FVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGS
                     ILGAVVFIVLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGA
                     LVATYVRLSTTLEITAGDAVVKLQTDVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLI
                     AVTVVLGIVGKFCHFL"
     gene            12824..13258
                     /gene="agaF"
                     /locus_tag="ACHY1N_004026"
     CDS             12824..13258
                     /gene="agaF"
                     /locus_tag="ACHY1N_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactosamine/N-acetylgalactosamine
                     transporter subunit IIA"
                     /protein_id="HFS4046235.1"
                     /translation="MLSIILTGHGGFASGMEKAMKQILGEQSQFIAIDFPETSSTALL
                     TSQLEEAIAQLDCEDGIVFLTDLLGGTPFRVASTLAMQKPGCEVITGTNLQLLLEMVL
                     EREGLSGEEFRVQALECGHRGLTSLVDELGRCHEECPVEEGI"
     gene            13255..14388
                     /gene="nagA"
                     /locus_tag="ACHY1N_004027"
     CDS             13255..14388
                     /gene="nagA"
                     /locus_tag="ACHY1N_004027"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFS4046236.1"
                     /translation="MTPVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDA
                     ELLCPAYIDTHVHGGAGVDVMDDAPDVLDKLAMHKAREGVGSWLPTTVTAPLNTIHAA
                     LKRIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAQPPELFRELEIAELDQLIAVSQHT
                     LRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMT
                     GLHHREPGMVGAGLTDKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGM
                     PDGRYTLCGEEVQMHGGVVRTASGGLAGNTLSVDAAVRNMVELTGVTPAEAIHMASLH
                     PARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF"
     gene            14739..15893
                     /gene="agaS"
                     /locus_tag="ACHY1N_004028"
     CDS             14739..15893
                     /gene="agaS"
                     /locus_tag="ACHY1N_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AgaS family sugar isomerase"
                     /protein_id="HFS4046237.1"
                     /translation="MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNF
                     LEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPA
                     HPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALL
                     MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGV
                     FGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDNET
                     LVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAIAAESTDIVAAGPHIILPPSRHFI
                     DVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA"
     gene            15906..16766
                     /gene="kbaY"
                     /locus_tag="ACHY1N_004029"
     CDS             15906..16766
                     /gene="kbaY"
                     /locus_tag="ACHY1N_004029"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaY"
                     /protein_id="HFS4046238.1"
                     /translation="MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSP
                     VILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAM
                     IDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA
                     KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFV
                     RRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKIN
                     VCGSANRISA"
     gene            16933..17409
                     /gene="agaB"
                     /locus_tag="ACHY1N_004030"
     CDS             16933..17409
                     /gene="agaB"
                     /locus_tag="ACHY1N_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactosamine transporter subunit IIB"
                     /protein_id="HFS4046239.1"
                     /translation="MSSPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDD
                     IQQKLMGITAETYGFGIRFFTIEKTINVIGKAAPHQKIFLICRTPQTVRKLVEGGIDL
                     KDINVGNMHFSEGKKQISSKVYVDDQDLADLRFIKQRGVNVFIQDVPGDQKEQIPD"
     gene            17448..18251
                     /gene="agaC"
                     /locus_tag="ACHY1N_004031"
     CDS             17448..18251
                     /gene="agaC"
                     /locus_tag="ACHY1N_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactosamine transporter subunit IIC"
                     /protein_id="HFS4046240.1"
                     /translation="MHEITLLQGLSLAALVFVLGIDFWLEALFLFRPIIVCTLTGAIL
                     GDIQTGLITGGLTELAFAGLTPAGGVQPPNPIMAGLMTTVIAWSTGVDAKTAIGLGLP
                     FSLLMQYVILFFYSAFSLFMTKADKCAKEADTAAFSRLNWTTMLIVASAYAAIAFLCT
                     YLAQGAMQALVKAMPAWLTHGFEVAGGILPAVGFGLLLRVMFKAQYIPYLIAGFLFVC
                     YIQVSNLLPVAVLGAGFAVYEFFNAKSRQQAQPQPVASKNEEEDYSNGI"
     gene            18241..19032
                     /gene="agaD"
                     /locus_tag="ACHY1N_004032"
     CDS             18241..19032
                     /gene="agaD"
                     /locus_tag="ACHY1N_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708938.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactosamine transporter subunit IID"
                     /protein_id="HFS4046241.1"
                     /translation="MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKK
                     IYKDDKPGLSAAMKDNLEFINTHPNLVGFLMGLLISMEEKGENRDTIKGLKVALFGPI
                     AGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGV
                     KAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDSTHSVALQQDFFDK
                     VFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL"
     gene            19033..19788
                     /gene="agaI"
                     /locus_tag="ACHY1N_004033"
     CDS             19033..19788
                     /gene="agaI"
                     /locus_tag="ACHY1N_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosamine-6-phosphate isomerase"
                     /protein_id="HFS4046242.1"
                     /translation="MERGTASGGASLLKEFHPVQTLQQVENYTALSERASEYLLAVIR
                     SKPDAVICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETF
                     LQQHIVQQLGLREDQLISFRSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLN
                     EPGESLQPACHISQLDARTQQHEMLKTTGRPVTRGITLGLKDILNAREVLLLVTGEGK
                     QDATERFLTAKVSTAIPASFLWLHSNFICLINT"
BASE COUNT         4862 a         5167 c         5043 g         4848 t
ORIGIN      
        1 ctcagaagag ttacttccag ataacaccct cgagaaagac gaaaattctc cggacaatgg
       61 ttttgaggtc ggggaatata acacatatga agcatataac tcagagaatc aatattttac
      121 cagagaggac tatacgtata attacgacct tttaaatgca atatagactt aataacttct
      181 tacaaagtct attattaata ccgtagatat ttattcatct taccctgtgc accaaaagca
      241 aaaactcact gacgcgggtt tgaaactgat ggcaaccgca aaaatgcctg atgcgctacg
      301 cttatcaggc ctacgccatc tctgcaatat attgaatttg cgtgcttttg taggcaggat
      361 aaggcgttca cgccgcatcc ggcatgaata aagcgcactc aacaatctga aacccgccgg
      421 aacggtttat tacgtacatc aggtgaaact gaccgataag ccgctttctt ttgggtatag
      481 cgtcgtggac agtcattcat ctttctgccc ctccaaaagc aaaaacccgc cggtttacgc
      541 tggcgggttt tcgttaaatc aggtgaaact gaccgataag ccgctttctt ttgggtatag
      601 tgtcgtggac agtcattcat ctttctgccc ctccaaaagc aaaaacccgc cgaagcgggt
      661 ttttacgtaa atcaggtgaa actgaccgat aagccgggtt ctgtcgtgga cagtcattca
      721 tctaggccag caatcgctca ctggctcaag cagcctaccc gggttcagta cgggccgtac
      781 cttatgaacc cctatttggc cttgctccgg gtggagttta ccgtgccacg gactgttacc
      841 agccgcgcgg tgcgctctta ccgcaccctt tcacccttac ctgatcccgc ttgcgcgggc
      901 catcggcggt ttgctctctg ttgcactggt cgtgggtttc ccccccaggc gttacctggc
      961 accctgccct atggagcccg gactttcctc ccctccgccc gtctcccccg aagaggacga
     1021 cgacgaagcg gcgactgtct ggtcagcttc ggcgcgcagt atagagggtt tgcgcgccct
     1081 tgtcaccccg cgttgcgcat tccaatcgcc agtgtcgcgg cgatattacg tgaagcacgg
     1141 cagatattgt cataagcccc gcggaatgct tcgtccaacg tacctatgct ggtcaatacg
     1201 ctgaagaccg catcgatgcc atgctgatgt acaacgccaa catcatcggt caggctaccc
     1261 gcaatgccaa tcaccggttt atggtacttc ttcgccacgt ttgcaacgcc aatcggtacc
     1321 ttgccgtgaa tactctggct gtcaatacgc ccttcaccgg tgatcaccag cgtacaatcg
     1381 tgaatatgtt cctccagatt cagcgccgta gtgacgattt caataccact tttcagttcc
     1441 gcaccaagaa acgccatcag cgccgcaccc ataccgcccg cagctcctgc gccggggaca
     1501 tctttcacat caacatgcag cgctttttta atgacctcgg catagtgaga gaggttattg
     1561 tccagctcaa caatcatcgc ttcactggct cccttttgtg ggccaaagat gcgcgatgcg
     1621 ccgttatcgc ccaccagcgg attggtgaca tcacaagcga cgcgaatgac gcaatctttt
     1681 aagcgcggat cgaggccgga aatatcaata tcattcagag tattaagact accgccgcca
     1741 aaaccaattt cattgccgtt ggcgtcgcat aatttcgccc ccagcgcctg taccatgcct
     1801 gcgccgccat catttgtagc gctaccgcca atgccgataa taatgtttgt cgcgccgctc
     1861 tccagcgcct gcaggattaa ctcgcctgtg ccgcgtgaag tggtcacgag tggatcgcgt
     1921 ttttccgcag gtaccagctc cagcccactg gccgccgcca tttcaataaa cgcggttttg
     1981 ccatcgccgg agatccccca actggcattc actttctcgc ccagcggccc tgtaacccag
     2041 gcgtgacgtt cagaaccctg ggtggctgca atcatcgctt ccaccgttcc ttcgccaccg
     2101 tcggcaaccg gaatagaaac gtactgtgca tcaggaaaaa tttcccgaaa tcctttttct
     2161 atcgcctgcg caacctcgct ggcagataaa ctttctttat aagagtctgg ggcgattacg
     2221 attttcatac ctatgcctgt taccacatga cgccggaggg cgtttctctt attcggcctg
     2281 gattccaggc ccggattgca atacgccatc cgggcacgac gtcattaacg agtaacttcg
     2341 actttcgcca gtttttcgta gtagcacgcc agggcgctat gatccgccgt tcctaaacca
     2401 tctgctcgca gtgcctgcat catctccata accgcagctg tgagcggcag ttgcgcgccg
     2461 acgccgtggg aagtatccag cgcatttgcc agatccttaa tatgcagatc aatacggaag
     2521 cccggcttga agttgcggtc catcaccatc ggcgctttgg catccagcac ggtactgccc
     2581 gccagtccac cgcgaattgc ctgatacacc aggtccgggt taacgcccgc tttggttgcc
     2641 agcgttagcg cttctgacat cgcggcaata ttcagcgcca caatgacctg atttgccagt
     2701 ttggtgacgt tacctgcacc gatttccccg gtatgcacca cggaacccgc catcgctttc
     2761 atcaaatcat agtatttgtc gaaaatagcc ttgtcgccgc ccaccatcac tgacagcgta
     2821 ccgtcgatgg ctttcggttc accgccgctc accggagcat ccagcatatc aatgcctttc
     2881 gctttcagcg cttcgctgat ttcacggctt gccagcggtg cgatagaact catatcgatc
     2941 aataccgtac ctggcttcgc gccttcaatg atgccattct cacccagcgc cacctctttc
     3001 acatgagggg agtttggcag catggttatg atgacgtcgc actgttcagc gatcgcttta
     3061 gccgtagacg ctgtttctgc acctgcagca atcacgtcag caatagcttc tgggttacgg
     3121 tcagcaacca ccagcgagta acctgctttc agaaggtttt tactcattgg tttacccata
     3181 atccccaggc caataaaacc aactttcata gtcatatcaa tcatctctct tgttgcggtg
     3241 gtggttattt tttaaaggta tcagccagtt tctgagtggc agagcggaag acgccaagat
     3301 cgctgccgac agccacaaac gtcgcgcccc attccagata acgacgcgca tcggcttcga
     3361 ccggcgcgag aataccgctg ggtttgccgt gcgcactggc acggttaaaa atgtgctgaa
     3421 ttgctttttg tacatccggg tgcgaggcat tgccgagatg gcctaatgcc gcagccagat
     3481 cgctggggcc gacgaagata ccgtctacac cttcggtagc ggcaatggca tcgacgttat
     3541 ctacgccctg ctgactttct atctggacca gaatggtgat gttcttgttc gactgagcga
     3601 aataatccgc cacggtgcca aacatattgg cgcggtgaga aacggagacg ccgcgaatgc
     3661 cttccggtgg gtaacgggtt gatgccaccg cctgctctgc ttcctctttt gtttctacaa
     3721 aaggaatcag gaagttatag aaaccgatat ccagaagacg cttaataatt accggctcgt
     3781 tggtcggcac tcgcactact ggcgcgctgg cgctgccttt cagggccatt aactgcggaa
     3841 taaacgtgga gatatcgttt ggcgcatgtt cgccatccag caccagccag tcaaacccag
     3901 ccaaaccaag aacttcagtg ctaatcgggt tagagagtgc tgaccagcaa ccaatttgta
     3961 cctgtttcgc agccagtgcg gctttgaatt tattcgggaa aacatcgtta ttcatcgctt
     4021 atacctttgc ttatttctgc aattccatac gtttaatgtc gccaactacg aagaggtagc
     4081 agaccatcgc catcagcgct gaacatccca cgaaaaccag tgctgcattg aaggagtgca
     4141 gttcacttac caggtagcca atcaccagtg gagtgacaat ggaggcaaca ttgccaaaga
     4201 cgttaaagac gccgccacag aggccaacaa tctctttcgg cgcggtgtca gaaatcaccg
     4261 gccagcccag agcaccaaat cctttgccaa aaaaagccag cgccattagc atgaccacca
     4321 gcgtggtgtt gttggtgtag ttacataaga tgatggtgga agccagcaac attcccagca
     4381 caatcggtag cttacgtgcc agggtcaggg ataaaccgcg tttgatcaga taatccgaga
     4441 agacacctcc cagcacgccg cccgcaaaac cacacagtgc cggaatcgag gcgaccagac
     4501 ccactttcag aatcgacatg cctttttcct gcaccagata aatcgggaac caggtgagga
     4561 agaaccaggt gatggtgttg ataaaatatt gtccgaaaaa tacgcccaac atcatgcggt
     4621 tagagagcaa ttgcttgatg taatgcagtt tgggaccgct tgctgccgca ctgcccggct
     4681 ttttgtggtc catatcgacc accgcgccat tttcagagat aaacttcagc tcttccgcag
     4741 acatacgtgg gtgatctgtc gggttatgaa tcaatttgat ccacagcgcc gtcagcacaa
     4801 aaccaatcac ccccataacg gtaaagacgt gctcccagcc ccaggcgaaa gtcagccagc
     4861 caagcagagg cgaaaagagc gccagcgaga aatattgcgc cgagttaaag atggcggagg
     4921 cagtaccacg ttctttcgtc gggaaccagg cggcgacaat acgggcgttc gccgggaatg
     4981 atggcgcttc cgagaagccg agcataaagc gcataaagaa catggagatc cctgcccagg
     5041 ccagcgggaa catatcaaca aagccttgca ggaaagtgaa tagcgaccag aaaaagaggc
     5101 tataggtata aacttttttc gagccaaact tatcaagcag ccagccgccg gggatttgca
     5161 tcagcaagtg ggcccagcca aaagcagaaa agatgtaacc catcgaaacc gcacttaact
     5221 gcaactcttt tgccacttcg gtaccagcaa tagacagcgt tgcacgatcg gcgtagttaa
     5281 cggcggtaac aataaaaata atcagtaata ttaaatagcg ggtatgcacg tctttctttt
     5341 tttcgtcaac ggtgtccaga atcattttat ttacctcggg tacttatgct gatttttatt
     5401 attatgggga aggtgttatt tatgagtttc atttatgccg taacggcaat gaactcggga
     5461 attagtataa gcagcgcgag aataataatc attgtgcaaa tgctaattta attaatgcta
     5521 tttaaatatt attttgagca tatgcacata aggttgcgcg ctaaagcaca gatttgcgct
     5581 ttaccttgcc gggcggcact gcaatccctg aaatgattga cattgatcac atttctgcgt
     5641 ttaaactcct gacattctta tttcacccaa tgaagtcatt tatttttaaa tgagaccagg
     5701 tcctcatttt aataacccct ggctggagaa tatagtacaa tggccaacat cgaaatcaga
     5761 caagaaacgc caactgcgtt ttatataaaa gttcacgaca cagataatgt ggcaattatt
     5821 gttaatgata atggcctgaa agcaggaacg cgttttccgg atggactgga attaattgaa
     5881 catattcccc aggggcataa agtcgcattg ctggacattc cggctaatgg tgaaattatt
     5941 cgttatggtg aagtgattgg ttacgccgtg cgtgcaatcc ctcgcggaag ctggatcgac
     6001 gaatcaatgg ttgtactacc ggaagcgccg ccgttacaca cgctgccact ggcaaccaaa
     6061 gtcccggccc ccttaccgcc gctggaagga tacacctttg agggctatcg caatgccgat
     6121 ggcagcgtgg gcaccaaaaa cctgctcggc atcaccacca gcgtccactg tgtggcaggc
     6181 gtggtggact atgtagtaaa aatcattgaa cgcgatctgc taccgaaata cccgaacgtc
     6241 gatggcgtgg tggggctgaa tcatttgtac ggctgtggca tggcgattaa cgcaccggcg
     6301 gcagttgtgc ctattcgtac catccacaat atttcgctga accctaactt tggcggcgaa
     6361 gtaatggtga ttggtctggg ttgtgaaaag ttgcagcctg agcgcctgct ggtcggcacg
     6421 gatgatgtgc aagctattcc agtagaaagc gccagcattg tcagtttgca ggatgaaaag
     6481 catgtcggtt ttcagtccat ggtcgaggat attttgcagg tcgccgaacg ccatctacaa
     6541 aaactgaatc aacgtcagcg agaaacctgt ccggcttcag aactggttgt cggcatgcag
     6601 tgcggtggca gcgatgcctt ttctggcgta acggcaaacc cggcggttgg ctatgcgtct
     6661 gatctactgg tgcgctgcgg cgcaacggtg atgttctcag aagtcacgga agtgcgtgac
     6721 gcgatccatc tgctgacacc acgcgcagtg aacgaagagg tcggcaaacg gctgctggag
     6781 gagatggagt ggtacgataa ctatctcaat atgggaaaaa ccgaccgcag cgccaaccct
     6841 tcgccgggca acaagaaagg cggtctggca aacgtggtag agaaggcact cggctccatt
     6901 gctaaatcgg gtaaaagcgc aattgttgaa gtgctgtcgc ccggtcaacg cccgactaaa
     6961 cgcggattaa tttacgccgc gacgccagcc agcgattttg tctgtggcac gcaacaggtg
     7021 gcttcgggta tcaccgtgca agtgtttacg accggtcgtg gtacgccgta cggcctgatg
     7081 gcggtacccg tcattaaaat ggcgacccgc accgagctgg cgaaccgctg gtttgattta
     7141 atggatatta acgcgggcac tatcgccacc ggcgaagaaa ccattgaaga ggtgggctgg
     7201 aagttgttcc actttattct cgacgtcgcc agcgggaaga agaaaacctt ctcggatcaa
     7261 tgggggctgc ataaccagct ggcagtgttt aacccggcac cggtgacctg atttcttttg
     7321 gaacgtccct cgcaaaacat ggccttagtg ccatgttttt attgtttaaa gcccccacgt
     7381 ccattaataa tgcatttgca ttaccttagt tcaagcttat aatttgagca gaaaacaggc
     7441 tgtaaaagga cagtgaatca tgcccgctaa tgctcgctct cacgctgtac tgaccactga
     7501 atcaaaggtc acgatacgcg gacaaacaac tatccccgcg ccagtgcgtg aggccttaaa
     7561 actgaagcca ggccaggaca gcattcatta cgaaattctg cctggtgggc aagtctttat
     7621 gtgccgactg ggagatgaac aggaggatca tactatgaat gcatttttgc gttttctgga
     7681 tgcagatatc cagaacaacc cgcaaaaaac tcgtccattc aacattcaac aaggaaagaa
     7741 acttgtcgct ggcatggacg tcaacattga tgatgagatt ggcgacgacg aataatggat
     7801 tttccacaaa gggttaatgg ttgggcgcta tatgctcatc cctgttttca ggaaacctac
     7861 gacgctttag ttgccgaagt cgagacatta aagggaaaag atcctgaaaa ttatcagaga
     7921 aaagccgcca caaagttatt ggcggtagtc cataaagtga ttgaggagca tatcacggtc
     7981 aatccatcat caccggcatt ccgtcatggc aagtcgttag gctctgggaa aaataaagac
     8041 tggtcacggg taaaatttgg tgctggtcgt tatcgtctct tctttcgtta tagtgaaaaa
     8101 gagaaagtca tcattctggg atggatgaac gatgaaaaca ctctgcgcac ctacggtaaa
     8161 aaaacagatg cctataccgt attcagcaaa atgttaaaaa gaggacatcc tcctgccgac
     8221 tgggaaagcc tcacccaaga gacagaagaa aaccattgat ggtgttcaca atgcccgccg
     8281 aacgtattcg tgttgaccag cgggcaccct ttctcactcc ccgaccagaa tcacttcaac
     8341 cccagccttt cgcagtcctt ccagactatc cgcaggaatg ccttcatcaa caatgatcat
     8401 gtcgatacgt tgagtatcaa tgatcttatg taaactggaa cgattgaatt tactggaatc
     8461 ggtgaccacg atgatccgtt ccgcaacttc gcacatccga cggtttaaac gggcttcatc
     8521 ttcattatgt gtgctgacgc cgcgctccag atcgatcgca tctacaccaa gaaacagcat
     8581 atcgaagtgg taattttgca gcgattgctc agcctgatcg ccgtaaaaag attgcgactg
     8641 acggcgcaaa tgcccgccgg tcatcagcag ctcaacgcct tccgcttcca gcaacgcatt
     8701 agccacgttc ataccgttgg tcatcgcaat tacgtcagtg tgcttacgca tcagacgagc
     8761 aatctcaaaa gtggtagtcc cggaatcgag gatcacccga tgaccaggct gaatcaactc
     8821 aacggcagct ttcgcaacgc tgcgtttcat cgcggtgttc agcgcgcttt tatcttccac
     8881 tgatggctcg actgacggcg tcgtgctatc gcagatcaac gcgccaccat aggcacgcac
     8941 agcgatcccc tgcttttcca gaaacgccag atcattgcgg atcgtcacag tagatacgcc
     9001 atacaatgcc gacagatcgt taacctgcac actcccttgc tgtcgcagac gctgaatgat
     9061 ctgttctcgt cgctcgctgg tgccagtcac tcgcttctca cctgaagcgt cggtattact
     9121 catagtaagt cctttcgtaa aactttcgtt tcatttcgtt ttgcctatta acgcctttct
     9181 attaagcaaa tgcaagccca ccttgcccat tgacgcaagc tactctcgtt tcagtgactt
     9241 tcattatgtt tcttttgtga atcagatcag aaaactatta tctttcgttt tatttttatc
     9301 tcaccatgac gcagtatcaa ctgaaacaaa acgaaagatt aatatcgcag taatctgaac
     9361 tggagaggaa agtgaaacat ctgacagaaa tggtgagaca gcacaaagcg ggcaaaacaa
     9421 atggaattta tgccgtttgt tccgcacatc cgctggtgct ggaggctgca atccgctaca
     9481 ccagtgcaaa ccaaacgccg ttactgattg aagcaacctc caatcaggta gaccagttcg
     9541 gcggttatac cggaatgacg cccgccgatt ttcgcggctt tgtttgtcag ctcgccgact
     9601 cgttgaattt cccgcaggat gcgttgattc tgggtggtga ccatctgggg ccaaaccgct
     9661 ggcaaaacct gccggccgct caggcaatgg ccaatgccga tgatttgatt aaaagctacg
     9721 ttgcggcagg attcaaaaaa atccaccttg attgcagcat gtcctgtcag gacgatccga
     9781 ttcccttaac tgatgacatc gtggctgaac gcgccgcccg tctggcgaaa gtggcggaag
     9841 aaacctgtct tgaacacttt ggcgaagccg atctggagta tgtcattggt accgaagtgc
     9901 cggtacctgg cggcgcgcat gaaaccttaa gcgagctggc ggtcaccacg ccggatgccg
     9961 cccgcgccat gctggaagcc catcgtcacg cctttgaaaa gcaaggtttg aatgccatct
    10021 ggccacgcat cattgccctg gtggttcaac ccggcgtcga attcgatcac accaacgtta
    10081 ttgattatca gcccgccaaa gcgagcgcct taagccagat ggtcgaaaac tacgaaacgc
    10141 tgattttcga agcgcactct accgattatc aaacgccgca atcgctgcgc cagctggtga
    10201 ttgaccactt tgccattctg aaagttggcc cagcgctgac cttcgccctg cgtgaagctc
    10261 tgttctctct ggcggcgatt gaagaagaac tggtgccagc gaaagcctgt tctggtctgc
    10321 gtcaggtgct ggaagacgtg atgctcgacc gcccggaata ctggcaaagc cactaccacg
    10381 gtgacggcaa cgcgcgtcgt ctggcgcgtg gttatagcta ctcggatcgc gtgcgctatt
    10441 actggccgga cagccagatt gatgacgctt tcgctcatct ggtacgtaat ctggcggatt
    10501 caccaattcc gctgccgctg atcagccagt atctgccgct gcagtacgtg aaagttcgct
    10561 ccggcgagct gcagccaacg ccacgggaac tcattatcaa ccatattcag gacatcctgg
    10621 cgcagtacca cacagcctgt gaaggccaat aagcaaaaca aagaggaaca cgctatgcca
    10681 aatattgttt taagccggat tgatgaacgc ttgattcacg gtcaggtcgg cgttcaatgg
    10741 gtcggatttg cgggggcaaa tctggtgctg gtagccaacg atgaggttgc cgaagatccg
    10801 gtacaacaaa acctgatgga aatggtactg gcagaaggga tcgccgtacg tttctggacg
    10861 ctgcaaaaag ttatcgacaa cattcatcgc gccgccgatc gacagaaaat cctgctggtt
    10921 tgtaaaacac ccgccgattt cctgacgctg gtgaaaggtg gcgttccggt gaatcgcatt
    10981 aacgttggca atatgcacta cgccaatggc aaacaacaaa tcgccaaaac ggtttctgtg
    11041 gatgcgggcg atatcgcagc atttaacgac ctgaaagccg ctggggtgga atgcttcgtt
    11101 cagggcgtcc cgacagagcc tgctgtggac ctctttaaat tactttgagg gattcatcat
    11161 ggaaatcagc ctgttgcagg catttgcgtt gggcattatc gcctttatcg ctggcctgga
    11221 tatgtttaac ggcctaacac atatgcaccg cccggtggtc ctcggcccgt tggtcgggct
    11281 ggtacttggc gatctgcata ccggaatttt aaccggcggt acgctggaac tggtgtggat
    11341 ggggctggcc ccgctggcgg gcgcacagcc gcctaacgtg attatcggta ctatcgtcgg
    11401 cacggcgttt gccattacta ctggcgtgaa acccgatgtc gcggtcggtg tcgccgtacc
    11461 tttcgctgtc gcagtacaga tggggattac cttcctgttc tcggtgatgt ctggcgtgat
    11521 gtctcgctgc gaccggatgg cggagaacgc cgatactcgc ggcattgaac gcgtgaacta
    11581 tctggcactg ctggcactcg gcactttcta ttttctctgc gctttcctgc ctatctactt
    11641 cggcgcggaa catgcaaaaa ccatcattga tgtcctgccg caacgattaa tcgacggcct
    11701 cggcgtcgcg ggcggcatca tgccagcaat cggttttgcc gtgctgctga aaatcatgat
    11761 gaaaaacgtc tacatcccct acttcatcct gggctttgtt gccgcagcct ggctcaagtt
    11821 accggtgctg gctattgctg ccgctgcgct ggcgatggcg ctgatcgacc tgctgcgtaa
    11881 atctcctgaa ccgactcaac ctgcggcaca gaaagaggaa tttgaagatg gcatctaatc
    11941 aaaccaccct gccgaacgtc agtgaaaacg aagaaacatt gctgactggc gtcaatgaaa
    12001 acgtgtatga agatcagagc attggcgcgg agctgacgaa aaaagatatc aaccgcgtcg
    12061 cctggcgttc catgctgtta caagcgtctt ttaactacga acgtatgcag gcttctggct
    12121 ggttgtacgg tctgctgcct gctctgaaaa agatccacac taataaacgc gacctggcgc
    12181 gcgccatgaa ggggcatatg ggtttcttca atacccatcc gtttctggtg acatttgtta
    12241 tcggcattat ccttgcgatg gagcgttcta agcaggacgt taacagtatt cagagcacca
    12301 aaattgccgt cggtgcgccg ctcggcggga ttggcgatgc aatgttctgg ctaacgctac
    12361 tgccgatttg tggcgggata ggcgcaagcc ttgcgctaca aggctctatt cttggcgcag
    12421 tcgtatttat tgtgctgttc aacgtggtac acctggggct gcgttttggt ctggcgcatt
    12481 atgcttaccg catgggcgtg gcggcgattc cactcattaa agcgaatacc aaaaaagtcg
    12541 gccatgctgc gtctatcgtt gggatgacgg taatcggcgc gctggtggca acctatgttc
    12601 gtttaagcac cacgctggaa atcacagcgg gcgacgcagt ggttaagtta cagactgatg
    12661 ttattgacaa actgatgcct gccttcttac cgctggtcta caccttgacc atgttctggc
    12721 tggtacgccg cggctggagt ccgctgcgcc tgattgcagt taccgtggtt ctcggcatcg
    12781 tcggtaaatt ctgccatttc ctttaaatac aatgaggtat tagatgttaa gtattatttt
    12841 gacagggcat ggcgggtttg ccagtggcat ggaaaaagca atgaagcaaa tcctcggcga
    12901 gcaatcgcag tttattgcca tcgattttcc cgaaacctca agcaccgcgc tgcttacatc
    12961 gcagcttgaa gaggccatcg cccaactgga ttgtgaagac ggcattgttt ttctgactga
    13021 tttgctgggc ggcacgccgt ttcgcgtagc ttcaacgctg gcgatgcaaa aaccgggctg
    13081 tgaagtgatc accggcacca atttacaact gctactggag atggtgctgg agcgcgaagg
    13141 gttaagcggt gaagagttcc gtgtgcaggc gctggagtgt ggacatcgtg ggctgaccag
    13201 tctggtagac gagttaggcc gctgccatga agaatgtccg gtcgaggaag gaatatgaca
    13261 cccgttctgc gcgccagaag gctgctgact gaagagggat ggctcgatga ccatcagttg
    13321 cgtattgctg acggtgtcat cgcagcaatc gaaccgattc cagtgggcgt gactgaacgc
    13381 gatgcggaac tgctctgccc tgcttacatc gacacccatg tacacggggg tgcgggcgtt
    13441 gatgtaatgg atgacgcgcc ggatgtactc gacaagctgg caatgcacaa ggcacgcgaa
    13501 ggtgtcggca gttggttacc gaccaccgta accgcgccgc ttaataccat tcatgcggcg
    13561 ctgaaacgta ttgctcaacg ttgccaacgc ggcggacctg gtgcgcaagt gctggggagt
    13621 tatctcgaag gaccgtactt cacgccgcag aataaaggcg cgcaaccgcc agaattgttt
    13681 cgcgagcttg aaattgccga gctggatcaa ttgattgccg tttctcagca caccttacgc
    13741 gtggtagcgc tggcaccgga aaaagagggg gcattgcagg ccatccgcca tcttaaacag
    13801 caaaatgtac gagtgatgct ggggcatagc gcggcgacct ggcaacaaac tcgcgccgcg
    13861 tttgatgctg gtgccgacgg cctggtgcat tgctataacg ggatgacagg tttacatcac
    13921 cgcgaaccgg gaatggttgg cgcgggatta acggacaagc gcgcctggct ggaactgata
    13981 gccgatggtc atcatgtgca tccggcggca atgtcgctgt gttgttgctg tgcgaaagag
    14041 agaatcgtac tgatcaccga cgcgatgcag gcagctggga tgccggatgg tcgctatacg
    14101 ttatgtggtg aagaagtgca gatgcacggt ggcgttgtcc gtaccgcgtc tggtgggctg
    14161 gcgggcaata cgctgtctgt tgatgcggca gtgcgcaata tggtcgagtt gacgggcgta
    14221 acgcctgcgg aagccatcca tatggcgtcg ctgcatccgg cgcgaatgct gggtgttgat
    14281 ggtgttctgg gatcgcttaa accgggcaaa cgcgccagcg tcgttgcgct ggatagcggg
    14341 ctacatgtgc aacaaatctg gattcagggt caattagctt cgttttgatg gtttgctcca
    14401 ttattgggcc ttcacttccc ccgtaaggcc tttctttttc tttctttttg atctgtgcag
    14461 cggtgtcgga tgcgacgcta acgcgtctta tgcgacctac ggtacgccgc atccggcaat
    14521 cggtgaacat agcgacgtca ttacgcaatt ctttaatctt cccttgtctt ttctttcaac
    14581 gatcacagat ttcgttttat ttcctttttc ttcattgaac tttctgtttc ttttctatag
    14641 attttaatca acgaaagaca tcaccaagtg aaattaaacg aaaggcaagt gaaagcgaca
    14701 acgcccgacg tcaagttcat cagactaagg attgagttat gccagaaaat tacacccctg
    14761 ctgccgccgc aaccggtaca tggactgaag aagagatccg ccatcagcct cgcgcatgga
    14821 tccgttcact caccaacatc gacgcgctac gttccgcgct caataacttc cttgaaccgt
    14881 tactgcgcaa agagaatctg cggatcatcc tgaccggagc cggaacctcg gcatttatcg
    14941 gtgacatcat cgcgccgtgg ctcgccagcc ataccggtaa aaacttcagc gccgtaccga
    15001 ccaccgatct ggtcactaat ccgatggact acctgaaccc agcccatccg ctgctgttga
    15061 tctccttcgg tcgatccggc aacagcccgg aaagcgtcgc tgccgtggaa ctggcaaatc
    15121 aatttgtacc agaatgctat cacctgccga tcacctgcaa cgaagcgggc gctctttacc
    15181 aaaacgcgat caacagcgat aacgcgtttg ccctgctgat gcccgcagaa acgcacgatc
    15241 gcggctttgc gatgaccagc agcattacca ccatgatggc cagctgcctc gcggttttcg
    15301 cacctgagac gatcaacagc caaaccttcc gcgacgtggc ggatcgttgc caggcgatcc
    15361 tgacctcact gggcgatttc agcgaaggtg tgtttggtta cgcaccgtgg aaacggatcg
    15421 tttatctcgg cagcggtggc ttacagggcg cagcacgcga gtcggcgctg aaagtgctgg
    15481 aactgacggc gggtaaactg gcggcctttt atgattctcc aaccggattc cgtcatggac
    15541 caaaatcgct ggtcgataac gaaacactgg tggtggtatt tgtctccagc cacccttaca
    15601 cccgtcagta tgatcttgat ctgctggctg aactccgccg tgacaaccag gcaatgcgcg
    15661 taatcgccat cgccgcggaa agcaccgaca tcgtcgctgc cggtccacat attatcctgc
    15721 cgccgtcacg tcactttatc gacgttgagc aggcattttg cttcctgatg tacgcccaga
    15781 cgtttgcact gatgcagtcg ctgcacatgg gcaatacgcc ggatacccca tcagccagtg
    15841 gcaccgttaa ccgcgtggtg caaggcgtaa tcattcatcc gtggcaggca taagaggatc
    15901 gcattatgag cattatctcc actaaatatc tgttacagga cgcccaggcc aatggctacg
    15961 cggtgcctgc ttttaacatt cataacgccg agacgatcca ggcgatcctc gaagtgtgca
    16021 gtgaaatgcg atcgccggtg atcctcgccg gaacgccggg gacctttaaa catatcgcgc
    16081 tggaagagat ctacgccctg tgcagcgcct attccacaac ctacaacatg ccactggcgc
    16141 tgcatctcga ccaccacgaa tcgctggatg atattcgccg taaagtccac gcaggtgtgc
    16201 gcagtgcaat gatcgacggc agccacttcc cgtttgccga gaacgtgaag ctggtgaaat
    16261 cggttgttga cttctgccac tcacaggatt gcagcgtgga agcagaactg ggccgcctgg
    16321 gcggtgttga agatgacatg agcgttgacg ccgaaagtgc attcctgacc gatccacaag
    16381 aagctaaacg ctttgtcgaa ctgactggcg tcgacagcct ggcggtagcg attggtacgg
    16441 cgcacggctt atacagcaaa acgccgaaga ttgatttcca gcggctggcg gaaattcgtg
    16501 aagtggtgga tgttcctctg gtgctacatg gtgccagcga tgttccggat gaatttgtcc
    16561 gtcgcactat tgaacttggc gtcacaaaag tgaacgttgc cacagaatta aaaatagcct
    16621 tcgctggcgc ggttaaagcc tggtttgcgg aaaatccgca gggtaatgat cctcgttatt
    16681 atatgcgcgt cggaatggat gcgatgaaag aagttgtcag aaataaaatt aatgtctgtg
    16741 gttcagcgaa tcgaatttca gcataatcat tagtttttta tgatttatcc caatgtactt
    16801 cccgattaat atcggggagt gccttaatgg aaaaggagat gactaaacct taataaatac
    16861 atcagtacaa tatcgcaaca ataatatatt aaaaaaaatc atattattca actttatggt
    16921 gaggattaca caatgagcag tccaaatatt ctcttaaccc gtattgataa ccgtctggtt
    16981 cacggtcagg ttggcgtgac ctggacatcc accatcggtg cgaatctgct ggtagtcgtg
    17041 gatgatgttg tcgctaacga tgatattcaa cagaaattaa tgggtattac cgcagaaacc
    17101 tacggctttg gcattcgttt ctttactatc gaaaaaacca ttaacgtcat cggcaaagct
    17161 gcaccgcatc agaagatctt cctgatttgc cgtacgccac aaacggtacg taaattggta
    17221 gaaggtggca ttgacctgaa agatatcaac gtcggcaata tgcatttctc ggaagggaaa
    17281 aagcaaatca gcagtaaagt ttatgtcgat gaccaggatc tcgcggactt acgttttatt
    17341 aaacaacgtg gcgtgaatgt tttcattcag gacgtccctg gcgatcaaaa agaacaaatc
    17401 cctgactaaa tctaaaatcg ccttaatatt ggtttgaggt aataaaaatg catgaaataa
    17461 ccctacttca gggattatcc ctggcggcgt tagttttcgt tctggggatt gatttttggc
    17521 tggaagcctt atttttattc cgcccgataa tcgtttgtac cctaactggc gctattctcg
    17581 gtgatattca gactggctta attaccggtg gtctgacaga gttggctttc gccggattaa
    17641 cccctgcagg tggtgttcag ccgcccaacc cgattatggc gggtctgatg accaccgtca
    17701 ttgcatggtc tacgggcgtt gatgccaaaa cagcaattgg tcttggcctg ccgtttagtt
    17761 tgttaatgca gtacgtcatt ctgttcttct attccgcttt ctcattattt atgaccaaag
    17821 ccgataaatg cgcgaaagag gcggatacgg cagcgttttc ccggcttaac tggacaacga
    17881 tgctcatcgt cgcttcagcg tatgcggcga ttgctttcct ctgtacttac ctggcacaag
    17941 gggcgatgca ggcgctggtg aaagcgatgc ccgcctggtt gacccacggc tttgaagtgg
    18001 ctggcggtat tctgcctgcc gttggttttg gcttgctgct gcgcgtaatg ttcaaagcgc
    18061 aatatatccc ttacctgatc gctggcttcc tgtttgtttg ctacatccag gtcagcaacc
    18121 tgttgccggt tgccgtactg ggtgcaggct ttgcggtgta tgagtttttc aatgcgaaat
    18181 cccggcagca agcgcaaccg cagcccgttg ccagtaaaaa tgaagaagag gactacagca
    18241 atgggatctg aaatcagtaa aaaagatatc acccgtctgg gctttcgttc gtcgctgctg
    18301 caagcgagct ttaactacga aaggatgcag gcgggcggtt ttacctgggc gatgttgccg
    18361 atcctgaaaa agatttataa ggacgacaaa ccgggcttaa gcgcggcgat gaaagataac
    18421 ctcgaattta ttaataccca cccgaatctg gtcggattcc tgatggggtt attaatttcg
    18481 atggaagaaa aaggagaaaa ccgcgacact attaaaggcc tcaaagtggc actgtttggc
    18541 ccaattgccg ggattggcga tgcgattttc tggtttactt tgttgccgat tatggcggga
    18601 atttgctcat catttgccag ccagggaaac ctgctggggc cgattctatt tttcgccgtt
    18661 tacctgctta tctttttcct gcgcgtcggc tggacccacg tcggttattc agtcggcgtg
    18721 aaggcgatcg ataaagtgcg agagaactcg cagatgattg ctcgctcggc aaccatcctc
    18781 gggatcacgg taatcggcgg gctgatcgct tcgtatgtgc atattaacgt ggtgacatcg
    18841 tttgccatcg acagtaccca cagcgtcgcg ctgcaacagg atttcttcga taaagtcttc
    18901 ccgaacattt taccgatggc ctacaccctg ctgatgtatt acttcctgcg ggtgaaaaaa
    18961 gcgcatccgg tgctgttaat cggcgtgact tttgtgctct ctattgtttg ttccgcattc
    19021 ggcattttgt aaatggaacg aggcactgcg tctggcggtg cctctttact taaggaattt
    19081 catcctgtgc aaacccttca gcaagttgaa aactatacgg cgttaagtga acgtgccagc
    19141 gaatatttat tggccgtgat ccgtagcaaa ccggatgccg tgatttgcct ggcgaccgga
    19201 gccacgccat tactgacgta tcattatctg gtagaaaaaa tccaccagca gcaggttgat
    19261 gtcagccagc tcaccttcgt gaagctcgac gaatgggtgg atctgccatt aacgatgcct
    19321 ggtacctgcg aaactttcct gcaacagcat atcgtgcagc agctggggct acgtgaagac
    19381 cagctcatca gctttcgctc cgaagagata aatgagacag agtgcgaacg ggtaacgaac
    19441 ctgattgcgc gcaaaggcgg tctggattta tgcgttctag gattggggaa aaacggtcat
    19501 cttgggctga acgaaccggg agaaagccta caaccggcct gccatatcag tcaacttgat
    19561 gccagaacac agcaacatga gatgttaaaa accacgggtc gccccgtgac tcgtgggatc
    19621 accttaggcc tgaaggatat tctcaatgcc cgcgaggttt tgttattggt gactggcgaa
    19681 ggaaagcagg atgcgacaga acgttttctc acggctaaag tctccaccgc tatcccggct
    19741 tcgtttttat ggctgcacag taactttatt tgtttaatta atacctaacc agatgaaaat
    19801 ttgctcaaaa tttttaaatt aacttattca acagtcacgc attatattaa ataacatttg
    19861 actgggttga acataacgcc aatagcaaaa ggagttatgt tcaacaattt aattttagat
//
LOCUS       DAZUDJ010000079        19662 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.079, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000079 DAZUDJ010000000
VERSION     DAZUDJ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19662
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.079"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..138
                     /locus_tag="ACHY1N_004034"
     CDS             <1..138
                     /locus_tag="ACHY1N_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 family protein"
                     /protein_id="HFS4046243.1"
                     /translation="YRWHGSAEAHTCREVQDIPGVLAVFAERRKDSFGLYVRLMSVTL
                     N"
     gene            301..669
                     /locus_tag="ACHY1N_004035"
     CDS             301..669
                     /locus_tag="ACHY1N_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HFS4046244.1"
                     /translation="MSDTLSGTTHPDDNHDHPWWGLPCTVTPCFGVCLVQEGNRLHYL
                     ADRAGIRGLFSDADAYHLDQAFPLLMKQLELMLTSGELSPRYQHTVTLYAKGLTCEAD
                     TLGSCGYVYLAVYPTPEMKN"
     gene            759..1085
                     /locus_tag="ACHY1N_004036"
     CDS             759..1085
                     /locus_tag="ACHY1N_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TA system toxin CbtA family protein"
                     /protein_id="HFS4046245.1"
                     /translation="MKTLPDTHVREASRCPSPVIIWQTLLTRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQSGFSACTHSQLINSIDILRARRATG
                     LMTRDN"
     gene            1133..1621
                     /locus_tag="ACHY1N_004037"
     CDS             1133..1621
                     /locus_tag="ACHY1N_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5983 family protein"
                     /protein_id="HFS4046246.1"
                     /translation="MKLALTPEADSVNVQALNMGRIVVDVDGIELAELINVVCDNGHS
                     LRVVDESDRASTDCTPSFAALTGIRCSTAHITAKDNAWLYSLSHQTNDTGESEWIHFT
                     GSGYLLRTDAWSYPVLRLKRQGLSKTFRRLVVTLIRRYGVSLIHLDASAECLPGLPTF
                     DW"
     gene            1633..1830
                     /locus_tag="ACHY1N_004038"
     CDS             1633..1830
                     /locus_tag="ACHY1N_004038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HFS4046247.1"
                     /translation="MKSLTTETALDILIAWLQDNIDCESGIIFDNDEDKTDSAALLPC
                     IEQAREDIHTLRQLQLLQQNR"
     gene            1915..2757
                     /locus_tag="ACHY1N_004039"
     CDS             1915..2757
                     /locus_tag="ACHY1N_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HFS4046248.1"
                     /translation="MSDITISRPELVNRHTDVICSTSIRHILAVRKSALLQIDTLIRQ
                     LAEISAMTESIGGKTAPAWAMKQDFRCGCWLMEKPETAMKAITRNLDREIWRDLMQRS
                     GMLSLMDAQARDTWYQSLEYDNFPEISEANILSTFEQLHQNKDEVFERGMINVFRGLS
                     WNYKTNCPCKFGSKIIVNNLVRWDRWGFHLITGQQADRLADLERMLHLFSGKPIPDNR
                     ENITIHLDDHIQSVQCKEDYEDEMFSIRYFKKGSAHITFRKPELVDRLNDIIAKHYPG
                     ALAM"
     gene            complement(3100..3636)
                     /gene="yghD"
                     /locus_tag="ACHY1N_004040"
     CDS             complement(3100..3636)
                     /gene="yghD"
                     /locus_tag="ACHY1N_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GspM family type II secretion system protein
                     YghD"
                     /protein_id="HFS4046249.1"
                     /translation="MLRDKFIHYFQQWRERQLSRGEHWLAQHLAGRSPREKGMLLAAV
                     VFLFSVGYYVLIWQPLSERIEQQETMLQQLVAMNTRLKNAAPDIIAARKSATTTPAQV
                     SRVISDSASAHSVVIKRIADRGENIQVWIDPVVFNDLLKWLNALDEKYALRVTQIDAS
                     AAEKPGMVNVQRLEFGRG"
     gene            complement(3638..4816)
                     /gene="gspL"
                     /locus_tag="ACHY1N_004041"
     CDS             complement(3638..4816)
                     /gene="gspL"
                     /locus_tag="ACHY1N_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009276 - Gram-negative-bacterium-type
                     cell wall [Evidence IEA];
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HFS4046250.1"
                     /translation="MSSILEIFFPLCAADPIHWQRRTPDVEHGIWSDVANEQLQQWLQ
                     TDAIRLYIPGEWISVWQVELPDVARKQIPTILPALLEEELNQDIDELHFAPLNIDQQL
                     ATVAVIHQQHMRNIAQWLQENGITRATVAPDWMSIPCGFMACDAQRVICRIDECRGWS
                     AGLALAPVMFRAQLNEQDLPLSLTVVGIAPEKLSAWAGADAERLTVTALPAVTTYGKP
                     EGNLLTGPWQPRVSYRKQWARWRVMILQILLILVALAVERGVTLWSVSEQVAQSRTQA
                     EEQFLTLFPEQKRIVNLRSQVTMALKKYRPQADDTRLLAELSAIASTLKSASLSDIEM
                     RGFTFDQKRQILHLQLRAANFASFDKLRSALATDYVVQQDALQKEGDAVSGGVTLRRK
                     "
     gene            complement(4813..5790)
                     /gene="gspK"
                     /locus_tag="ACHY1N_004042"
     CDS             complement(4813..5790)
                     /gene="gspK"
                     /locus_tag="ACHY1N_004042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HFS4046251.1"
                     /translation="MITSPPKRGMALVVVLVLLAVMMLVTITLSGRMQQQLGRTRSQQ
                     EYQQALWYSASAESLALSALSLSLKNEKRVHLAQPWASGPRFFPLPQGQIAVTLRDAQ
                     ACFNLNALAQPTTASRPLAVQQLIALISRLDVPAYRAELIAESLWEFIDEDRSVQTRL
                     GREDSEYLARSVPFYAANQPLADISEMRVVQGMDAGLYQKLKPLVCALPMIRQQININ
                     TLDVTQSVILEALFDPWLSPVQARALLQQRPAKGWEDVDQFLAQPLLADVDERTKKQL
                     KTVLSVDSNYFWLRSDITVNETELTMNSLIVRMGPQHFSVLWHQTGESE"
     gene            complement(5793..6392)
                     /gene="gspJ"
                     /locus_tag="ACHY1N_004043"
     CDS             complement(5793..6392)
                     /gene="gspJ"
                     /locus_tag="ACHY1N_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001691118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HFS4046252.1"
                     /translation="MRRTRAGFTLLEMLVAIAIFASLALMAQQVTNGVTRVNSAVAGH
                     DQKLNLMQQTMSFLTHDLTQMMPRPVRGDQGQREPALLAGAGVLASESEGMRFVRGGV
                     VNPLMRLPRSNLLTVGYRIHDGYLERLAWPLTDAAGSVKPTMQKLIPADSLRLQFYDG
                     TRWQESWSSVQAIPVAVRMTLHSPQWGEIERIWLLRGPQ"
     gene            complement(6389..6760)
                     /gene="gspI"
                     /locus_tag="ACHY1N_004044"
     CDS             complement(6389..6760)
                     /gene="gspI"
                     /locus_tag="ACHY1N_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001709020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HFS4046253.1"
                     /translation="MKRGFTLLEVMLALAIFALAATAVLQIASGALSNQHVLEEKTVA
                     GWVAENQTALLYLMTREQRAVRHQGESDMAGSRWYWRTIPLNTGNALLQAVDIEVSRH
                     EDFSSVIQSRRAWFSAVGGQQ"
     gene            complement(6757..7320)
                     /gene="gspH"
                     /locus_tag="ACHY1N_004045"
     CDS             complement(6757..7320)
                     /gene="gspH"
                     /locus_tag="ACHY1N_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001394829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HFS4046254.1"
                     /translation="MPERGFTLLEIMLVIFLIGLASAGVVQTFATDSESPAKKAAQDF
                     LTRFAQFKDRAVIEGKTLGVLIDPPGYQFMQRRQGQWSPVSSTRLSAQVTVPKQVQML
                     LQPGSDIWQKEYALELQRRRLTLHDIELELQKEAKKKTPQIRFSPFEPATPFTLRFYS
                     AAQNACWAVKLAHDGALSLNQCDERMP"
     gene            complement(7324..7779)
                     /gene="gspG"
                     /locus_tag="ACHY1N_004046"
     CDS             complement(7324..7779)
                     /gene="gspG"
                     /locus_tag="ACHY1N_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003912123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HFS4046255.1"
                     /translation="MNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKA
                     DRQKAISDIVALENALDMYRLDNGRYPTTEQGLEALIQQPANMADSRNYRTGGYIKRL
                     PKDPWGNDYQYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ"
     gene            complement(7796..9019)
                     /gene="gspF"
                     /locus_tag="ACHY1N_004047"
     CDS             complement(7796..9019)
                     /gene="gspF"
                     /locus_tag="ACHY1N_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HFS4046256.1"
                     /translation="MALFYYQALERNGRKTKGMIEADSARHARQLLRGKELIPVHIEA
                     RMNTSSGGMLQRRRHAHRRVAAADLALFTRQLATLVQAAMPLETCLQAVSEQSEKLHV
                     KSLGMALRSRIQEGYTLSDSLREHPRVFDSLFCSMVAAGEKSGHLDVVLNRLADYTEQ
                     RQRLKSRLLQAMLYPLVLLVVATGVVTILLTAVVPKIIEQFDHLGHALPSSTRTLIAM
                     SDALQASGVYWLAGLLALLVLGQRLLKNPAMRLRWDKTVLRLPVTGRVARGLNTARFS
                     RTLSILTASSVPLLEGIQTAAAVSANRYVEQQLLLAADRVREGSSLRAALAELRLFSP
                     MMLYMIASGEQSGELETMLEQAAVNQEREFDTQVGLALGLFEPALVVMMAGVVLFIVI
                     AILEPMLQLNNMVGM"
     gene            complement(9019..10512)
                     /gene="gspE"
                     /locus_tag="ACHY1N_004048"
     CDS             complement(9019..10512)
                     /gene="gspE"
                     /locus_tag="ACHY1N_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HFS4046257.1"
                     /translation="MVPVAQETTANTVRLPYSFSRRFSLVAWCEASLEILHVHPLSLS
                     VLQELQRGLNAPFTLRQIDEAEFEQRLNAVWQRDSSEARQLMEDLGSAEDFFTLAEEL
                     PETEDLLESDDDAPIIKLINAMLAEAIKEGASDIHIETFEKSLVIRFRVDGTLHEMLR
                     PGRKLASLLVSRIKVMARLDIAEKRVPQDGRIALLLGGRAIDVRVSTMPSAWGERVVL
                     RLLDKNQARLTLERLGLSQQLTAQLRQLLHKPHGIFLVTGPTGSGKSTTLYAGLQELN
                     NHSRNILTVEDPIEYMIEGIGQTQVNTRVGMTFARGLRAILRQDPDVVMVGEIRDTET
                     AEIAVQASLTGHLVLSTLHTNTAVGAITRLQDMGVEPFLLSSSLTGVMAQRLVRTLCP
                     DCRQPAPATDEEKRLLGITDARTVTLYHPQGCPACNHKGFRGRTAIHELIVVDATLRD
                     LIHRQAGELELERYVRQHSAGIRSNGIEKVLAGETSLDEVLRVTMEA"
     gene            complement(10512..12572)
                     /gene="gspD"
                     /locus_tag="ACHY1N_004049"
     CDS             complement(10512..12572)
                     /gene="gspD"
                     /locus_tag="ACHY1N_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HFS4046258.1"
                     /translation="MFWRDITLSVWRKKTTGLKTKKRLLPLVLAAALCSSPVWAEEAT
                     FTANFKDTDLKSFIETVGANLNKTIIMGPGVQGKVSIRTMTPLNERQYYQLFLNLLEA
                     QGYAVVPMENDVLKVVKSSAAKVEPLPLVGEGSDNYAGDEMVTKVVPVRNVSVRELAP
                     ILRQMIDSAGSGNVVNYDPSNVIMLTGRASVVERLTEVIQRVDHAGNRTEEVIPLDNA
                     SASEIARVLESLTKNSGENQPATLKSQIVADERTNSVIVSGDPATRDKMRRLIRRLDS
                     EMERSGNSQVFYLKYSKAEDLVDVLKQVSGTLTAAKEEAEGTVGSGREVVSIAASKHS
                     NALIVTAPQDIMQSLQSVIEQLDIRRAQVHVEALIVEVAEGSNINFGVQWASKDAGLM
                     QFANGTQIPIGTLGAAISQAKPQKGSTVISENGATTINPDTNGDLSTLAQLLSGFSGT
                     AVGVVKGDWMALVQAVKNDSSSNVLSTPSITTLDNQEAFFMVGQDVPVLTGSTVGSNN
                     SNPFNTVERKKVGIMLKVTPQINEGNAVQMVIEQEVSKVEGQTSLDVVFGERKLKTTV
                     LANDGELIVLGGLMDDQAGESVAKVPLLGDIPLIGNLFKSTADKKEKRNLMVFIRPTI
                     LRDGMAADGVSQRKYNYMRAEQIYRDEQGLSLMPHTAQPVLPAQNQALPPEVRAFLNA
                     GRTR"
     gene            complement(12602..13561)
                     /gene="gspC"
                     /locus_tag="ACHY1N_004050"
     CDS             complement(12602..13561)
                     /gene="gspC"
                     /locus_tag="ACHY1N_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HFS4046259.1"
                     /translation="MARVVFRDARIYLIQWLTKIRHTLNQRQSFNTDKEHLRKIVRGM
                     FWLMLLIISAKVAHSLWRYFSFSAEYTAVSPSANKPPRADAKTFDKNDVQLISQQNWF
                     GKYQPVATPVKQPEPVPVAETRLNVVLRGIAFGARPGAVIEEGGKQQVYLQGETLGSH
                     NAVIEEINRDHVMLRYQGKIERLSLAEEGHSTVAVTNKKAVSDEAKQAVAEPAVSAPV
                     EIPTAVRQALAKDPQKIFNYIQLTPVRKEGIVGYAVKPGADRSLFDASGFKEGDIAIA
                     LNQQDFTDPRAMIALMRQLPSMDSIQLTVLRKGARHDISIALR"
     gene            complement(13579..13989)
                     /gene="gspS2"
                     /locus_tag="ACHY1N_004051"
     CDS             complement(13579..13989)
                     /gene="gspS2"
                     /locus_tag="ACHY1N_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system pilot lipoprotein
                     GspS-beta"
                     /protein_id="HFS4046260.1"
                     /translation="MSIKQMPGRVLISLLLSVTGLLSGCASHNENASLLAKKQAQNIS
                     QNLPIKSAGYTLVLAQSSGTTVKMTIISEAGTQTTQTPDAFLTSYQRQMCADPTVKLM
                     ITEGINYSITINDTRTGNQYQRKLDRTTCGIVKA"
     gene            complement(14055..14864)
                     /gene="pppA"
                     /locus_tag="ACHY1N_004052"
     CDS             complement(14055..14864)
                     /gene="pppA"
                     /locus_tag="ACHY1N_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417446.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase PppA"
                     /protein_id="HFS4046261.1"
                     /translation="MLFDVFQQYPAAMPILATVGGLIIGSFLNVVIWRYPIMLRQQMA
                     EFHGEMSSAQSKISLALPRSHCPHCQQTIRVRDNIPLLSWLMLKGRCRDCQAKISKRY
                     PLVELLTALAFLLASLVWPESGWALAVMILSAWLIAASIIDLDHQWLPDVFTQGVLWT
                     GLIAAWAQQSPLTLQDAVTGVLVGFITFYSLRWIAGIVLRKEALGMGDVLLFAALGGW
                     VGPLSLPNVALIASCCGLIYAIITKRGSTTLPFGPCLSLGGIATLYLQALF"
     gene            complement(15012..19574)
                     /gene="sslE"
                     /locus_tag="ACHY1N_004053"
     CDS             complement(15012..19574)
                     /gene="sslE"
                     /locus_tag="ACHY1N_004053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein metalloprotease SslE"
                     /protein_id="HFS4046262.1"
                     /translation="MNKKFKYKKSLLAAILSATLLAGCDGGGSGSSSDTPPVDSGTGS
                     LPEVKPDPTPNPEPTPEPTPDPEPTPEPTPDPEPTPEPEPEPVPTKTGYLTLGGSLRV
                     TGDITCNDESSDGFTFTPGDKVTCVAGNNTTIATFDTQSEAARSLRAVEKVSFSLEDA
                     QELAGSDNKKSNALSLVTSMNSCPANTEQVCLEFSSVIESKRFDSLYKQIDLAPEEFK
                     KLVNEEVENNAATDKAPSTHTSPVVPVTTPGTKPDLNASFVSANAEQFYQYQPSEIIL
                     SEGRLVDSQGYGVAGVNYYTNSGRGVTGENGEFSFSWGETISFGIDTFELGSVRGNKS
                     TIALTELGDEVRGANIDQLIHRYSTTGQNNTRVVPDDVRKVFAEYPNVINEIINLSLS
                     NGATLDEGEQVVNLPNEFIEQFKTGQAKEIDTAICAKTDGCNEARWFSLTTRNVNDGQ
                     IQGVINKLWGVDTNYKSVSKFHVFHDSTNFYGSTGNARGQAVVNISNAAFPILMARND
                     KNYWLAFGEKRAWDKNELAYITEAPSIVRPENVTRETATFNLPFISLGQVGDGKLMVI
                     GNPHYNSILRCPNGYSWNGGVNKDGQCTLNSDPDDMKNFMENVLRYLSNDRWLPDAKS
                     SMTVGTNLDTVYFKKHGQVLGNSAPFAFHKDFTGITVKPMTSYGNLNPDEVPLLILNG
                     FEYVTQWGSDPYSIPLRADTSKPKLTQQDVTDLIAYMNKGGSVLIMENVMSNLKEESA
                     SGFVRLLDAAGLSMALNKSVVNNDPQGYPDRVRQRRSTPIWVYERYPAVDGKPPYTID
                     DTTKEVIWKYQQENKPDDKPKLEVASWQEEVEGKQVTQFAFIDEADHKTPESLAAAKQ
                     RILDAFPGLEVCKDSDYHYEVNCLEYRPGTGVPVTGGMYVPQYTQLDLGADTAKAMLQ
                     AADLGTNIQRLYQHELYFRTNGLQGERLNSVDLERLYQNMSVWLWNETKYRYEEGKED
                     ELGFKTFTEFLNCYTNNAYVGTQCSAELKKSLIDNKMIYGEESSKAGMMNPSYPLNYM
                     EKPLTRLMLGRSWWDLNIKVDVEKYPGAVSEEGQNVTETISLYSNPTKWFAGNMQSTG
                     LWAPAQKEVTIKSNANVPVTVTVALADDLTGREKHEVALNRPPRVTKTYSLDASGTVK
                     FKVPYGGLIYIKGDSKDNESASFTFTGVVKAPFYKDGAWKNDLNSPAPLGELESDAFV
                     YTAPKKNLNASNYTGGLKQFANDLDTFASSMNDFYGRNDEDGKHRMFTYKNLTGHKHR
                     FANDVQISIGDAHSGYPVMNSSFSTNSTTLPTTPLNDWLIWHEVGHNAAETPLTVPGA
                     TEVANNVLALYMQDRYLGKMNRVADDITVAPEYLEESNGQAWARGGAGDRLLMYAQLK
                     EWAEKNFDIKKWYPEGSLPAFYSEREGMKGWNLFQLMHRKARGDEVGKTKFGERNYCA
                     ESNGNAADTLMLCASWVAQTDLSEFFKKWNPGANAYQLPGASEMSFEGGVGQSAYNTL
                     ASLKLPKPEQGPETINQVTEHKMSVE"
BASE COUNT         4455 a         5538 c         4942 g         4727 t
ORIGIN      
        1 taccgctggc acggcagcgc tgaagcacat acctgtcgtg aagtgcagga tattcccggc
       61 gtgctggctg tgtttgccga acgccgtaag gacagttttg gcctgtatgt ccggctgatg
      121 agcgtcaccc tgaactgatg ttccgtcacc cggaaaacga gtacgactgg ctgagctcag
      181 acgccgctgt ggatgaggtc ctgctcatca acgaatacac ctttaccgaa gccggtctgc
      241 gcgccggctg acccgtcatc gttaaactat cattcaccga ttttctgtga ggattttatc
      301 gtgtcagaca cactctccgg gacaacgcat cccgatgaca atcacgacca tccctggtgg
      361 ggactaccct gcacagtgac gccctgtttc ggcgtctgtc tggtgcagga gggtaaccgg
      421 ttgcattacc ttgccgaccg cgccggtatc agaggcctgt tcagcgatgc agatgcgtac
      481 cacctggacc aggcctttcc gctgctgatg aaacaactgg agctcatgct caccagtggt
      541 gaactcagcc cccgctatca gcataccgtc acgctgtatg cgaaaggact gacctgcgaa
      601 gccgataccc tgggctcctg tggttacgtt tatctggctg tttatccgac gcccgaaatg
      661 aaaaattaac tctccagaat agccttctgc tacggcctgg tgttttcacc acgccacttt
      721 cccatttctc atctctgcat atcaggaaaa ccttcagtat gaaaacatta cccgatacac
      781 acgtacggga ggcatcgcgc tgcccgtctc ccgtcatcat ctggcagaca ctgctcaccc
      841 gactgctgga ccagcactac ggcctcacgc tgaatgacac accgttcgct gatgaacgtg
      901 tgattgagca gcatattgag gcaggcattt cactgtgtga cgcggtgaac tttctcgttg
      961 aaaaatacgc gctggtacgt accgaccagt cgggattcag cgcctgtacc cactctcagt
     1021 taataaacag catcgatatc ctccgggctc gccgggcaac aggcctgatg actcgcgaca
     1081 attaaagaac ggtaaataac attaccctgg gtaaacatcc aggggcgaaa caatgaaact
     1141 ggccctgaca ccggaagccg acagcgttaa cgtacaggca ctgaacatgg ggcgcattgt
     1201 cgttgacgtc gatggtattg agcttgctga actgattaac gtggtctgcg ataacggtca
     1261 ctcccttcgt gttgttgatg aatctgaccg agcctcaaca gactgcacgc catcatttgc
     1321 tgccctgact ggcatacgct gcagtaccgc gcatatcacg gcaaaagaca acgcctggct
     1381 gtactcgctg tcgcatcaga cgaatgacac cggcgaatca gaatggattc attttacagg
     1441 cagcggatat ctgttacgta ccgatgcgtg gtcatacccg gttctgcggc ttaagcgcca
     1501 gggcctgtca aaaacgttcc gccgtctggt tgtcacactc atccgacgtt atggcgtcag
     1561 tctcattcat ctggatgcca gcgctgaatg cctgccgggt ttacccactt tcgactggta
     1621 accaggaaca acatgaaatc attaaccacg gaaaccgcac tggatattct gattgcgtgg
     1681 ctgcaggaca atatcgactg cgaatcggga attatctttg acaacgatga ggataaaaca
     1741 gattcggcag cactgctgcc ctgcattgaa caggcgaggg aggatatcca taccctgcgc
     1801 caactgcagc ttctgcaaca gaaccggtga gtcttactca ccagacttca ttccactgac
     1861 gccagcctga atacggctgg cgttttcgtt tataaaccaa aaggaaaaac gatgatgtca
     1921 gatatcacaa tctcccgccc ggaactggtc aacagacata cggacgttat ctgctcaacc
     1981 agtatccgcc acattttggc tgtacgaaag agtgcgctgc tgcaaatcga cacacttatc
     2041 cggcaactgg ctgaaatctc agcaatgaca gaaagtattg gcggtaaaac cgccccggcc
     2101 tgggccatga aacaggattt tcgctgcggc tgctggctga tggagaaacc ggaaaccgca
     2161 atgaaagcca tcacccggaa tcttgaccgc gaaatctggc gtgacctgat gcaacgttca
     2221 gggatgcttt ccttaatgga tgcacaggcc cgtgatacat ggtaccagtc actggagtac
     2281 gataattttc cggaaatcag tgaagcgaac attctgagca catttgaaca actgcaccag
     2341 aacaaagatg aagtgtttga gcgggggatg atcaacgtct tcaggggact gagctggaat
     2401 tacaaaacca attgcccctg caagtttggc agtaaaatta tcgtcaacaa cctggtaagg
     2461 tgggacagat gggggtttca tcttatcacc gggcaacagg ccgatcgact tgccgatctg
     2521 gaaagaatgc tgcacctgtt cagcggcaaa ccgatccccg acaaccggga aaacatcacc
     2581 attcatctgg atgaccacat ccagtctgtt cagtgtaaag aggactatga agatgagatg
     2641 ttcagcatca gatactttaa gaagggctcc gcacacatca cgttcaggaa accagaactg
     2701 gttgacaggc ttaatgatat tattgccaag cactatcccg gagcgttagc gatgtaaaaa
     2761 ggaataaaac tcaggaataa aacccacaaa aatacacgtg ttctgatgac aaaaatcttg
     2821 atctacttgt tctcataaaa accaccagaa gggaccgagg gtacaagaga gggtacattt
     2881 ttcatcaaac caaataaacg agattaatat caacatgata acaaccatat tcgattccga
     2941 gtccggcacc actaattctt aagaacccgc ccacaaggcg ggtttttgct tttggatctg
     3001 acaataacct tcacgaaaaa aattagctta taaagtctgg gggaattact ctcgccacgt
     3061 taacgagagt aattttattg atattaatct cctgatactt tacccccgtc caaactccag
     3121 ccgctgcaca ttcaccatcc caggcttctc agcagcactg gcatcaattt gtgtcacccg
     3181 cagcgcatac ttttcatcca gcgcgtttaa ccatttcagc aggtcattaa acaccaccgg
     3241 atctatccag acctgaatat tctccccacg atcggctatc cgcttgatga ctaccgagtg
     3301 cgcggaagca ctgtcactga tgacccgcga tacctgcgca ggcgttgttg tggcagattt
     3361 tcgcgctgca ataatatccg gcgcggcgtt cttcagtcgg gtgttcatcg ccaccagttg
     3421 ctgcaacatt gtctcctgtt gctcaatccg ttcgctcaaa ggctgccaga tgaggacgta
     3481 atatccgacg ctaaacagga acaccaccgc tgccagtaac atgccctttt cacgcggaga
     3541 acgccccgcc aggtgttgtg ccagccagtg ttcgccacgg cttaactggc gttcacgcca
     3601 ttgctgaaaa tagtgaataa atttatcgcg taacatgtta tttcctccgc aacgttacgc
     3661 cgccggaaac cgcatcaccc tctttctgta acgcgtcctg ttgcacaaca taatcggttg
     3721 ccagtgcact acgcagtttg tcgaaactgg caaagttcgc ggcccgtagc tggaggtgaa
     3781 gtatctggcg tttttgatca aaggtaaaac cacgcatttc gatgtcggaa agtgacgctg
     3841 atttcagggt gctggctatc gctgacaact cggcgagcag ccgggtatcg tcggcctgtg
     3901 ggcgatattt tttcagcgcc atcgtcacct gagagcgtaa attcacaatc cgcttctgct
     3961 ccgggaacaa cgttaagaac tgttcctccg cctgggtgcg gctttgcgcc acctgttcgc
     4021 tgacgctcca taacgtcacg ccccgctcca ctgccagcgc aaccagaatc agcaatatct
     4081 gcagaatcat cacccgccag cgcgcccact gttttcggta gctgacgcga ggctgccacg
     4141 gccctgtcag caggttccct tccggtttgc cataagtggt aacggcgggc agagctgtaa
     4201 cggtcaggcg ttcagcgtct gcgccagccc atgctgatag cttttccggt gcaatgccga
     4261 ctacggttag cgaaagcggt aaatcctgct cattgagctg ggcgcggaac atgaccggag
     4321 ccagcgccag cccggcgctc catccccggc attcatcgat gcggcagata acccgttgcg
     4381 catcgcaagc cataaaccca caaggaatgg acatccagtc cggcgcgacg gtagcgcggg
     4441 tgatgccgtt ttcctgcaac cactgcgcaa tgttgcgcat atgctgttgg tgaatcactg
     4501 ctacggttgc cagttgctgg tcgatattca acggggcgaa atgcagttca tcgatatcct
     4561 ggttcagctc ttcttccagt aaggcgggca gaatggtcgg tatctgctta cgggcgacat
     4621 caggcagttc aacctgccag acgctgatcc attcgccggg aatgtagagt cgaatcgcat
     4681 cggtttgcag ccattgctgg agctgttcgt tagcaacgtc agaccagata ccgtgctcca
     4741 catcgggtgt acggcgctgc caatggatgg gatcagcggc gcaaagcggg aaaaaaatct
     4801 caaggatgga actcactcac tttctcctgt ctgatgccag agaaccgaaa agtgttgtgg
     4861 gcccatgcgg acaattaacg agttcatcgt cagttcagtc tcattcacgg tgatatctga
     4921 acgcagccag aagtaattgc tgtccacgct caggacggtt tttagctgtt ttttagtacg
     4981 ctcatcgacg tcagcaagta gcggctgtgc aagaaactga tcgacatctt cccagccctt
     5041 cgccggacgt tgttgtaata acgcccgcgc ctgaacgggg cttaaccacg ggtcaaacag
     5101 cgcctcaaga atcacacttt gcgtgacgtc taaagtattg atgttgattt gctggcggat
     5161 catcggcagc gcacagacca gcggtttcag tttttgataa agcccggcgt ccattccctg
     5221 taccacgcgc atctcactga tatcagccag cggttgattc gcggcgtaga aaggcaccga
     5281 acgggcgaga tactcgctgt cttcacggcc cagacgtgtc tgcacgctgc ggtcctcgtc
     5341 aataaactcc cacaggcttt cggctatcag ttcggcccga taagcaggca catccaggcg
     5401 cgagatcagg gcaatcaact gttgtaccgc aagcggacgc gacgccgttg tcggctgagc
     5461 aagggcattc aggttaaagc aagcctgtgc gtcacgcagg gtgaccgcaa tttgcccctg
     5521 cggcagaggg aagaaacgag ggccggatgc ccacggctgt gccagatgca cgcgcttttc
     5581 atttttcagg ctcagactga gcgcgctcag cgccaggctt tccgcactgg cgctgtacca
     5641 cagcgcctgc tggtactcct gctggctgcg cgttcgccca agttgttgct gcatccgccc
     5701 ggaaagcgtg atggttacca gcatcataac cgccagcaat accagcacca cgaccagtgc
     5761 cattccgcgt tttggtggtg aggtgatcat gattattgcg gcccgcgtaa caaccagatg
     5821 cgttcaatct cgccccattg cggcgaatgc agggtcatgc gtaccgccac agggatcgcc
     5881 tgtactgacg accagctctc ctgccagcgc gtgccgtcgt agaactgcaa acggagcgaa
     5941 tcggccggaa tcaacttttg cattgtcggc ttcacgctgc ctgcggcatc ggtcagcggc
     6001 caggctaacc gttcgagata accgtcatga atgcggtaac cgacggtgag cagattactg
     6061 cgcggcagac gcatcaacgg gttaaccaca ccgccgcgca caaaacgcat tccttcactc
     6121 tcagacgcca gcacgccagc gccagccagt aacgctggtt cacgctggcc ctgatcgcct
     6181 cttaccggac gcggcatcat ttgggtcaga tcgtgggtca gaaaactcat cgtttgctgc
     6241 atgaggttta gtttttgatc gtgtccggcg acggcgctat tcacgcgcgt gacgccgtta
     6301 gtcacctgct gcgccatcag tgccagcgag gcaaaaatgg caattgccac cagcatttcc
     6361 agtaacgtga aaccagcgcg agtccttctc actgttggcc tcccacggcg ctaaaccagg
     6421 cgcgtcgtga ctgaatcacc gacgaaaagt cttcgtgacg gctgacttca atatccaccg
     6481 cctggagcag cgcgttgcct gtattcaatg ggattgttcg ccagtaccag cggcttcctg
     6541 ccatatcgct ctcaccctga tgcctgaccg cccgctgctc acgggtcatc aggtagagca
     6601 gcgcagtctg gttttcagct acccagcccg ctaccgtttt ttcctcaaga acgtgctgat
     6661 tactcagcgc accgctggca atctgtaaca ccgccgtggc agccagcgca aaaatcgcca
     6721 gcgcgagcat cacttccagc aaggtaaatc cgcgcttcat ggcatcctct catcacattg
     6781 attgagggat aacgcgccat cgtgtgccag ctttaccgcc caacatgcgt tttgcgccgc
     6841 cgagtagaag cgcagcgtaa acggcgtggc gggttcaaaa ggcgaaaaac ggatctgcgg
     6901 cgtcttcttt ttcgcctctt tttgcagctc aagttcaata tcgtgcagcg tcagtcgacg
     6961 acgttgcagc tccagcgcat attccttctg ccagatatca cttccgggtt gtaacagcat
     7021 ctgcacctgt ttcggcaccg taacctgtgc cgataaccgg gtcgaggaaa cgggcgacca
     7081 ctgcccctga cgacgctgca taaactggta gccaggcggg tcgattagca caccgagtgt
     7141 tttcccttcg atcactgccc tgtccttaaa ctgcgcaaag cgagtcagaa aatcctgcgc
     7201 cgcttttttc gcgggcgatt cagaatcggt cgcaaacgtc tgtactacgc ccgcactggc
     7261 aaggccgata aggaaaatca ccagcatgat ttccagaagt gtgaatccgc gttcaggcac
     7321 tgcttactga aactcctgca aattccagtt accgatatct gcgccagcgc cttccccgtt
     7381 ttcctgacca tccgccccca gggtataaac atcaaacagc cctttttcac ccggactgag
     7441 atactgataa tcattgcccc acggatcctt tggcagtcgt ttaatgtatc caccagtacg
     7501 gtagttgcgg gagtccgcca tattggctgg ctgctggatc agcgcctcaa gcccctgttc
     7561 tgtggtcgga taacgcccgt tatccagtcg gtacatatcc agtgcgtttt ccagcgccac
     7621 gatatcgctg atggcttttt gccgatcggc tttctctttg ttgcccaaca ggttaggcac
     7681 caccagactt gccaggacgc caagaataac aatcaccacc atcacttcca gcagggtaaa
     7741 acctgcccgt ggtttttgtg tgcgggataa cgaattcatg tgataactcc gtaaattaca
     7801 ttccaaccat attgttcagt tgcagcatcg gctcgaggat ggcgatgaca ataaacagca
     7861 ccacgcccgc catcatcacc accagcgcag gctcaaacag ccccaacgcc agccccacct
     7921 gggtatcaaa ttcccgttcc tggttgactg cggcctgctc aagcatggtt tccagttcgc
     7981 cgctctgttc gccggaggcg atcatgtaca gcatcattgg cgagaacagc cgcaactccg
     8041 ccagcgcggc gcgcagactg cttccttcgc ggacgcgatc tgccgccagc agtagttgtt
     8101 gttcgacata gcgatttgcc gacacggcag cagcggtctg aatgccttcc agtagcggaa
     8161 cactgctggc ggtgaggatg cttaaggtgc gggaaaaacg cgccgtattc agcccgcgcg
     8221 caacacgccc cgtcacaggc aggcgcagca cggttttgtc ccagcgcagg cgcatagcag
     8281 gatttttaag tagccgttgc cccagcacca gaagcgccag caatcccgcc agccagtaaa
     8341 cgccgctggc ctgtaacgca tcactcatgg caataagcgt gcgggtggag gagggtagcg
     8401 cgtgtccgag atgatcaaac tgttcgatga ttttcggcac cactgccgtc agcaaaatag
     8461 tgactacgcc cgttgccacc accagcagaa ccagcggata gagcatggcc tgcaatagac
     8521 gtgatttcag gcgctgtcgc tgttcggtgt aatctgccag gcgattgagc accacgtcga
     8581 gatgcccgga tttttctccg gcagcaacca tcgaacaaaa cagagaatca aagacgcggg
     8641 gatgttcgcg caggctgtcc gacagggtgt aaccttcctg aatccggctg cgcagcgcca
     8701 ttccgaggct ttttacatgc agtttttcac tttgctcact gaccgcctgt aagcaggttt
     8761 ccagcggcat tgctgcctgt accagcgttg ccagttggcg cgtgaacagc gcaagatctg
     8821 ccgccgccac gcgacgatgt gcgtgccgcc gacgctgcaa catcccccct gacgaagtat
     8881 tcatccgggc ttcaatatgc acggggataa gctctttacc gcgcaacaac tggcgggcat
     8941 gacgcgcgga atccgcctca atcatacctt tggttttgcg accattacgc tccagcgcct
     9001 gatagtaaaa cagtgccatt acgcctccat ggttacccgc agaacttcat cgagagaggt
     9061 ttctccggcg agcactttct caatgccgtt gctgcggata cccgcagagt gttgtcggac
     9121 ataacgttcc agctccagct ccccggcctg acggtggatc aaatcacgca atgtggcatc
     9181 caccacgatc agctcatgga tggcagtccg tccgcgaaaa cctttgtgat tacaggcggg
     9241 acagccctgt ggatggtaca gagtgacggt acgggcgtcg gtaattccca gcaggcgttt
     9301 ttcttcgtca gtggctggtg cgggctggcg gcagtcggga cacagcgtgc gaaccagtcg
     9361 ctgcgccatc acgcccgtca gactggaaga gagcaggaaa ggctccacgc ccatatcctg
     9421 caaacgtgtg atcgccccca ccgctgtgtt ggtatgcagc gtggaaagga ccaggtgtcc
     9481 ggtaagtgaa gcctggacgg cgatttctgc ggtttcggta tcgcggattt caccgaccat
     9541 caccacatcc gggtcctgac gcaaaatcgc gcgcagccca cgggcaaagg tcatgccgac
     9601 gcgggtgtta acctgcgtct gaccgatccc ttcaatcatg tattcgatgg gatcttcaac
     9661 cgtgagaatg ttgcgcgaat ggttgttcag ctcctgcaat ccggcgtaca gcgtggtgct
     9721 tttgccggaa cccgtcggcc ccgtcaccag aaagatgccg tgcggtttgt gtaacagctg
     9781 gcgcaactgc gcggtcagtt gctggctaag ccccagacgc tccagcgtca ggcgggcctg
     9841 gtttttgtcc agcagtcgca gcaccacgcg ctcgccccag gcagaaggca tggtggagac
     9901 acgcacgtca atcgcccggc cgcccagcaa cagcgcaata cgtccatcct gcggcacgcg
     9961 cttttcggca atgtccagcc gcgccatcac cttgatacgc gacaccagca gcgaggccag
    10021 tttgcgcccc ggacgcagca tttcatgtaa tgtgccgtca acacgaaaac ggatcaccag
    10081 actcttttca aacgtctcaa tgtggatatc cgaagcgcct tctttgattg cctctgccag
    10141 catggcgttg atcagtttga tgatcggcgc atcgtcgtcg ctttccagca gatcttccgt
    10201 ttccggcagt tcttccgcga gggtaaaaaa gtcctcggca gaaccgagat cttccatcag
    10261 ctggcgagcc tcggaagagt cccgctgcca gaccgcattc agccgctgtt caaattcggc
    10321 ctcgtcgatt tgccgcagcg taaagggcgc gttcagcccc cgctgcagct cctgcaaaac
    10381 agagagcgat agcggatgaa cgtggaggat ctccagcgac gcttcgcacc atgccaccag
    10441 gctaaaccga cggctgaaac tgtagggcag acgcacggtg ttggcggtgg tttcctgtgc
    10501 tacaggcacc attaacgcgt tctcccggca ttgaggaacg cgcgaacttc cggcggtaag
    10561 gcctggtttt gcgctggcag taccggctgt gcggtgtgcg gcatcaggct taaaccttgc
    10621 tcatcacgat agatctgttc ggcgcgcata tagttatatt tgcgctgcga cacgccgtct
    10681 gccgccatac cgtcacgcag aatggtcgga cggataaaca ccatcaggtt acgtttttct
    10741 tttttatccg ccgtcgattt aaacaggtta ccaatcaatg ggatatcgcc cagcagcggc
    10801 actttcgcca cgctttctcc cgcctgatcg tccatcagac caccaagcac aatcagctca
    10861 ccatcgttag ccagcacggt ggttttcagt ttgcgctcac caaacaccac gtcgaggctg
    10921 gtctgtcctt ccaccttcga gacttcctgc tcaatcacca tctgtaccgc gttaccttcg
    10981 ttaatctgcg gcgtgacttt cagcatgatg ccgacttttt tcctttctac tgtattgaaa
    11041 ggattgctgt tattggagcc aacggtagag ccggttaata ccggaacgtc ctggcccacc
    11101 atgaagaagg cttcctggtt gtccagcgtg gtgatgctcg gcgtggagag cacgttcgag
    11161 ctggagtcgt ttttaaccgc ctgcaccagc gccatccagt cgcctttcac cacaccaacc
    11221 gccgtaccgc taaagccgga aagaagctgg gcgagtgtgg agagatcgcc gttggtatcc
    11281 ggattaatgg tggtagcgcc gttttcactg atcaccgtcg agcctttctg cggtttcgcc
    11341 tgagaaatgg ctgcccccag cgtaccgata gggatctgcg taccattagc aaactgcatt
    11401 aatccggcat ctttcgacgc ccactgcacg ccgaagttga tattgctacc ttcggcaact
    11461 tccacgatca acgcctcgac gtgcacctga gcacggcgaa tatccagttg ttcaattacg
    11521 ctttgcagcg actgcatgat gtcctgcggc gcggttacaa tcagggcatt actgtgtttg
    11581 ctggcggcga tggatacaac ctcacgcccg ctaccgaccg tgccttccgc ctcttcttta
    11641 gccgccgtga gcgtgccgct gacctgtttc agcacatcga ccagatcttc ggctttgctg
    11701 tatttgagat agaaaacctg gctgttgccg ctgcgttcca tttctgagtc cagccgacgg
    11761 atcaggcggc gcattttgtc ccgcgtggcc gggtcaccac tgacaatcac actgttggtg
    11821 cgttcgtcgg cgacaatttg agatttcagc gtcgcaggct ggttctcgcc gctgtttttc
    11881 gtcaggcttt ccagcacgcg ggcgatttcc gaagccgagg cgttatccag cgggatcacc
    11941 tcttcggtgc gattacccgc gtgatccacg cgctggatca cttccgtcag gcgctccaca
    12001 acggaggcgc gtccggtgag cataatcacg ttggagggat cgtaattaac aacgttgcct
    12061 gagcctgcgc tgtcgatcat ctggcgcaga atcggtgcca gctcgcgtac cgacacatta
    12121 cgtaccggca ctactttggt gaccatttca tcgcccgcgt agttgtcgct gccttcaccg
    12181 accagcggca gcggctcgac tttcgcagcg ctggatttca ccaccttcag cacgtcgttt
    12241 tccatcggta cgacggcata cccctgtgct tccagcaggt taaggaatag ctggtaatac
    12301 tggcgttcat tgagcggggt catggtgcga atactcactt tcccctgtac gcccggcccc
    12361 ataatgatgg ttttattaag gttagcgccg acggtttcga tgaacgattt caggtcggta
    12421 tctttaaaat tagcggtgaa agtggcttct tccgcccaga ccggtgaact gcataatgcc
    12481 gctgccagca ccagcggcag taaacgcttt tttgttttga ggccagttgt cttcttacgc
    12541 cagaccgaca acgtaatatc acgccaaaac acgatgaatg attctcctgg attaaatgcg
    12601 gttagcgcag cgcgatggaa atgtcgtggc gcgcaccctt gcgtaaaacc gtaagttgaa
    12661 tggaatccat tgaaggtaac tgccgcatca gagcaatcat tgctcgtgga tcagtgaaat
    12721 cctgctgatt tagcgcaatg gcgatatcgc cttccttgaa accgctggca tcgaacagag
    12781 aacgatctgc ccccggcttc actgcataac cgacaattcc ctccttacgc acaggcgtaa
    12841 gctggatata gttaaaaatt ttctgcggat ctttcgccag tgcctgacgc acggcagtcg
    12901 ggatctccac tggcgcactg acagcaggtt cagcaacagc ttgctttgct tcgtcactga
    12961 cggctttttt gttggtcacg gctacggtgg aatgcccctc ttctgccagg ctcaggcgct
    13021 ctatttttcc ctgatagcgc agcatcacat ggtcgcgatt gatttcctca atcaccgcat
    13081 tgtgcgagcc aagcgtttca ccctgcaaat agacctgctg tttaccgcct tcttcaataa
    13141 ccgcgccggg tctggcacca aaggcaatcc cgcgcagcac cacattaaga cgcgtttctg
    13201 ccacaggcac aggttcgggt tgttttaccg gcgtggcgac gggctgatat ttgccaaacc
    13261 agttttgctg gctgattaat tgcacgtcat ttttatcgaa cgtttttgca tccgcacggg
    13321 gcggtttatt cgccgatggg gaaacagccg tatattccgc agaaaaggag aaatagcgcc
    13381 agagtgaatg cgccactttt gcagaaataa taagcagcat cagccagaac atcccgcgta
    13441 caatttttcg cagatgctct ttgtctgtat taaaagattg tctctggtta agagtgtgac
    13501 gaatttttgt cagccattga atgagataaa ttcgtgcgtc acgaaaaaca acccgcgcca
    13561 atttatatct acccgacgtt atgctttgac tattccacag gtggtacgat ccagtttccg
    13621 ctgatactgg ttacctgtac gtgtatcatt aatcgttatg ctgtaattaa ttccctcggt
    13681 aatcattaat ttcaccgttg ggtcagcgca catttgtcgt tgatagctgg ttaaaaaggc
    13741 gtcaggcgtc tgcgtggtct gagtccccgc ttcgctgata atggtcattt ttaccgtcgt
    13801 gccgctactt tgtgccagca ctaaggtata tcccgcagat ttaatcggca ggttttggct
    13861 gatattttgc gcctgttttt tcgccagtaa actggcattt tcattatggc tggcacagcc
    13921 acttaataat cctgtaacgc tcaacaatag cgatattaat accctccctg gcatttgttt
    13981 tatcgacata gtaaataatc tctaaggtta ttaataagag ttaaaatgtc actttgataa
    14041 tgacgtggtt atcattaaaa caatgcctgt agataaagtg ttgctatacc gcccagactt
    14101 aaacacggtc caaaaggcag tgtggttgat cctctttttg taataatggc atatatcagg
    14161 ccgcagcatg atgcgattaa agcaacattg ggcagtgata acggccccac ccagccacct
    14221 aacgcagcga acaataatac atcgcccatg cctaatgctt ctttacgcag aactattccg
    14281 gctatccagc gcagggagta aaaagtgata aaccccacca ggacgccggt aactgcgtct
    14341 tgtagcgtta acggactctg ttgcgcccat gccgcaatca gtcctgtcca caatacgccc
    14401 tgagtaaaaa catcgggcag ccattggtga tcgaggtcga tgatgctcgc ggcaatcagc
    14461 caggcggata atatcatcac cgccagcgcc catccacttt ccggccagac cagactcgcc
    14521 agcaaaaaag cgagtgccgt caataactcc accagcggat aacgcttgct gattttcgcc
    14581 tgacagtcgc ggcagcgccc tttgagcatc aaccaggaga gcagcggaat attgtcacga
    14641 acgcggatgg tctgctgaca atgtgggcag tgcgaacgcg gtagcgcaag gcttattttt
    14701 gactgcgcac tcgacatttc accgtgaaac tccgccattt gttggcgcag catgatgggg
    14761 taacgccaaa tcaccacatt caaaaaactg ccgatgatca atcctccgac ggttgccagt
    14821 atgggcatcg ccgcggggta ttgctgaaaa acatcaaaaa gcatggttaa aggttgtttg
    14881 ttgtaacttg ctggatgcgg gcctgcaagt gtatgccata cggctttcct ccaggcccga
    14941 taagctggcg caacccggta cgccttattt catgccggat gcggcgtgaa cgccttatcc
    15001 ggcatacagg attactcgac agacatctta tgctcggtaa cctgattaat ggtttccggt
    15061 ccctgttccg gtttcggcag cttgagcgac gccagcgtgt tgtatgccga ctggcccaca
    15121 ccgccctcga agctcatctc gctcgccccc ggcagctggt aagcattcgc acccggattc
    15181 catttcttaa agaactccga aagatccgtc tgggcgaccc aggaggcaca cagcatcagc
    15241 gtgtccgcag cgttaccgtt tgactcagca cagtaatttc tttcgccaaa cttggtttta
    15301 ccaacctcat cgccgcgtgc tttacgatgc atcaactgga acagattcca gcctttcatc
    15361 ccttcacgct cgctgtagaa cgctggcaga gagccttctg gataccattt cttgatatca
    15421 aagtttttct ctgcccattc cttcagttgt gcgtacatca gcagacggtc acccgcaccg
    15481 ccgcgcgccc atgcctgacc gttgctctcc tccagatatt ccggtgcgac ggtaatatcg
    15541 tcagcgacac ggttcatctt gccgagataa cgatcctgca tgtacagcgc cagcacgttg
    15601 ttcgccactt cggtcgcgcc tggaacagtc agcggcgttt ctgcggcgtt gtgccctact
    15661 tcgtgccaga tcagccagtc gttcagcggc gtcgtcggca gcgtggtgct gttcgtcgag
    15721 aagctgctgt tcattaccgg ataacccgaa tgcgcatcac cgatggagat ctgcacatcg
    15781 ttggcgaaac gatgcttgtg gcccgtcaag tttttatagg taaacatccg gtgcttaccg
    15841 tcttcatcat tacgaccgta gaaatcattc atcgagctgg caaaggtatc cagatcgtta
    15901 gcgaattgct tcagtccgcc agtgtaattg ctggcattca ggttcttctt cggtgcggta
    15961 taaacgaaag cgtctgattc cagctcaccc agcggagccg gtgagttcag atcgtttttc
    16021 catgcgccgt ctttatagaa cggtgctttt accacaccag taaaggtgaa gctggcagat
    16081 tcattgtctt tgctgtcgcc tttgatataa atcagaccac cgtaaggcac cttgaatttc
    16141 accgtaccac tagcgtccag agagtacgtt ttggttactc ttggcggacg gttcagcgcg
    16201 acttcatgct tctctcttcc ggtcaggtcg tcagccagcg ccacggtgac ggtcacagga
    16261 acgttcgcat tggacttaat ggtgacctct ttctgagccg gtgcccacag gccagttgac
    16321 tgcatgttac ctgcaaacca tttggtcgga ttcgagtaca ggctgatggt ttcagtaacg
    16381 ttctgtccct cttccgatac tgctcccgga tacttctcga catcaacttt gatgttcaga
    16441 tcccaccagg aacggcccag catcaggcgt gtcagcggtt tttccatata gttgagcggg
    16501 tagctcgggt tcatcatgcc cgctttgctg ctttcttcac cgtaaatcat cttgttatcg
    16561 atcagcgatt ttttcagctc agcggaacac tgcgtgccaa cgtatgcatt gttggtgtag
    16621 cagttcagaa actcagtgaa cgttttaaag cccagctcgt cttctttacc ctcttcataa
    16681 cgatatttcg tctcgttcca cagccagacg gacatgtttt ggtataaacg ttccagatcg
    16741 acgctgttga gacgctcacc ctggaggcca ttggtacgga aataaagctc atgctgatac
    16801 aggcgctgaa tattggtgcc taaatccgca gcctgcagca tcgctttcgc agtgtcagct
    16861 ccaagatcca gctgcgtata ctgcggaaca tacatgccac cggttaccgg cacacccgtg
    16921 cctgggcggt attccagaca gttgacctca tagtgatagt cagaatcctt acacacttcc
    16981 agccctggga acgcgtccag aattctctgt tttgccgcag ccagtgactc aggcgttttg
    17041 tggtcggctt catcaataaa ggcgaattgg gttacctgtt taccctcaac ttcttcctgc
    17101 cagctggcaa cttccagctt cggtttgtca tcaggtttgt tttcttgctg atatttccag
    17161 ataacttctt tcgtggtgtc atcaatggta tacggtggtt taccatcgac agccggataa
    17221 cgctcataga cccaaattgg cgttgaacgt cgttgacgaa cacggtcagg gtagccttgc
    17281 ggatcgttat ttactaccga cttgttaagc gccatcgaca aacctgcggc atcaagcaga
    17341 cgtacaaagc cagatgcgct ctcttcctta agattgctca tcacgttttc catgatcagc
    17401 accgatccac ctttgttcat ataggcgatc aaatcggtca catcctgctg ggtcagcttc
    17461 ggtttgctgg tatctgcgcg cagaggaatg gagtaaggat cgctacccca ttgtgtgacg
    17521 tattcaaagc cattgaggat caacagagga acttcatctg gattcagatt gccatagctg
    17581 gtcattggtt tgaccgtgat gccagtgaaa tccttgtgga acgcaaacgg tgcgctattt
    17641 cccagcacct gaccatgttt tttgaaatat accgtgtcca ggttagtacc cacggtcata
    17701 ctggattttg catccggcaa ccagcgatca tttgacagat agcgcagcac gttctccatg
    17761 aagttcttca tgtcatccgg gtcgctgttg agcgtacact gtccgtcttt attaacgccc
    17821 ccgttccagc tgtaaccgtt cgggcaacgc aggatgctgt tgtagtgtgg gttaccgata
    17881 accatcagct tgccatcgcc cacttgcccc agcgagataa acggcaggtt gaaggtggcg
    17941 gtttcgcgtg tcacgttctc tggtcgcaca atggaaggcg cttcagtaat gtacgccagc
    18001 tcatttttat cccaggcgcg tttttcgcca aacgccagcc agtagttttt atcattacgc
    18061 gccatcagaa tcgggaaggc cgcgttggag atattcacca ccgcctgacc gcgcgcatta
    18121 cccgtgctgc catagaagtt agtagagtca tggaatacat ggaacttgct gacagatttg
    18181 tagttcgtat ccacgcccca cagcttgttg ataacgccct gaatctggcc gtcattaaca
    18241 ttgcgcgtcg tcagcgagaa ccagcgagcc tcgttacaac cgtcggtttt cgcacaaatc
    18301 gcggtatcga tctctttggc ctgacccgtc ttaaactgct cgataaattc gtttggcaga
    18361 ttaacaactt gctcaccttc atccagcgtc gcaccgttgg ataacgagag attgataatc
    18421 tcgttgatca cgttgggata ttcggcaaag accttgcgta catcatccgg aacaacacgg
    18481 gtattatttt gcccggtcgt cgaatagcga tgaataagct gatcgatatt cgccccgcga
    18541 acttcatcac ccagttcagt cagcgcaatg gtcgacttat tgccgcgcac tgaacccagt
    18601 tcaaaggtat cgataccaaa ggagatggtt tcgccccagc taaaagaaaa ttcaccattt
    18661 tcccctgtca cgccacggcc tgaattggtg tagtagttga cgccagcaac accatatccc
    18721 tggctatcca ccaggcgacc ttctgagaga atgatttccg aaggttgata ctgataaaac
    18781 tgttccgcgt tagccgacac gaaggaggcg ttcagatccg gttttgttcc cggagtcgtg
    18841 acggggacta ccggtgaagt atgagtggat ggcgctttat cagtcgcggc attgttttcc
    18901 acctcttcat tgaccagctt tttgaactct tccggtgcca gatcgatttg cttatacagc
    18961 gagtcgaaac gtttactctc gatcaccgag gagaactcca ggcacacctg ttctgtattc
    19021 gccgggcaac tgttcatgga ggtgaccagc gagagcgcat tgcttttctt gttgtcggaa
    19081 cccgccagtt cttgcgcgtc ctcaagacta aacgacactt tttcaaccgc acgcaggcta
    19141 cgcgcagctt ctgactgggt gtcgaaggta gcaattgtcg tgttgttccc tgccacacag
    19201 gtgactttgt cgcctggtgt aaaggtaaag ccatcgctgg attcatcatt acaggtgata
    19261 tcaccagtta cccgcaggct tccgcccagg gtcagataac ccgttttcgt aggaacaggt
    19321 tctggctccg gttctggtgt tggctcagga tcaggtgtcg gttccggcgt aggttctggg
    19381 tccggcgttg gctcaggcgt cggctccggg tttggtgttg gatcaggttt cacttccggc
    19441 aaagaccctg ttccagaatc tacaggcggc gtatcggagg aagatccgga gccaccgcca
    19501 tcacaaccgg ctaacagggt tgcactcaaa atagccgcta aaagcgattt cttatattta
    19561 aatttcttat tcattaataa cgcaagtgac aaaacaatgt taaaaaattc gtaactggga
    19621 gaaatagttt tatgctttat cttctttaat aatttcctcc at
//
LOCUS       DAZUDJ010000080        19368 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.080, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000080 DAZUDJ010000000
VERSION     DAZUDJ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19368
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.080"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            451..900
                     /gene="alaE"
                     /locus_tag="ACHY1N_004054"
     CDS             451..900
                     /gene="alaE"
                     /locus_tag="ACHY1N_004054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HFS4046263.1"
                     /translation="MFSPQSRLRHAVADTFAMVVYCSVVNMCIEVFLSGMSFEQSFYS
                     RLVAIPVNILIAWPYGMYRDLFMRAARKVSPSGWIKNLADILAYVTFQSPVYVAILLV
                     VGADWHQIMAAVSSNIVVSMLMGAVYGYFLDYCRRLFKVSRYQQVKA"
     gene            complement(937..1281)
                     /locus_tag="ACHY1N_004055"
     CDS             complement(937..1281)
                     /locus_tag="ACHY1N_004055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2002 family protein"
                     /protein_id="HFS4046264.1"
                     /translation="MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARM
                     GRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVAL
                     ERYLNGLFGEAS"
     gene            1433..1762
                     /locus_tag="ACHY1N_004056"
     CDS             1433..1762
                     /locus_tag="ACHY1N_004056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HFS4046265.1"
                     /translation="MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAE
                     AARSKAQALLKETRARMHGRTRVQQAARDAVGCADSFVRERPWCSVGTAAAVGIFIGA
                     LLSMRKS"
     gene            2010..2255
                     /gene="nrdH"
                     /locus_tag="ACHY1N_004057"
     CDS             2010..2255
                     /gene="nrdH"
                     /locus_tag="ACHY1N_004057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFS4046266.1"
                     /translation="MRITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALR
                     AQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAASA"
     gene            2252..2662
                     /gene="nrdI"
                     /locus_tag="ACHY1N_004058"
     CDS             2252..2662
                     /gene="nrdI"
                     /locus_tag="ACHY1N_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFS4046267.1"
                     /translation="MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYIL
                     IVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCG
                     VPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA"
     gene            2635..4779
                     /gene="nrdE"
                     /locus_tag="ACHY1N_004059"
     CDS             2635..4779
                     /gene="nrdE"
                     /locus_tag="ACHY1N_004059"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFS4046268.1"
                     /translation="MATTTAECLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAF
                     IATHVRPNSVTFSSQQQRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHTSGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDATLALQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVLPDITFHLAKENAQMALFSPYDVERVYGKPFADVAISQHYDEL
                     VADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASEYDENLDYARTGHDISCNLGSLNIAHTMDSPNFARTVETAVRGLTAVSDMSH
                     IRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYTITWHALRT
                     SMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELFARSGITLPTREMW
                     AQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPA
                     PFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL"
     gene            4789..5748
                     /gene="nrdF"
                     /locus_tag="ACHY1N_004060"
     CDS             4789..5748
                     /gene="nrdF"
                     /locus_tag="ACHY1N_004060"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFS4046269.1"
                     /translation="MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLTVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMPDALTPHEEAVLSNISFMEAVHA
                     RSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNMEKISLGQREEL
                     KSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMA
                     EVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF"
     gene            6103..7305
                     /gene="proV"
                     /locus_tag="ACHY1N_004061"
     CDS             6103..7305
                     /gene="proV"
                     /locus_tag="ACHY1N_004061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0031460 - glycine betaine transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein ProV"
                     /protein_id="HFS4046270.1"
                     /translation="MAIKLEIKNLYKIFGEHPQRAFKYIEQGLSKEQILEKTGLSLGV
                     KDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRE
                     VRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHS
                     YPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTI
                     VFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSA
                     KDIARRTPNGLIRKTPGFGPRSALKLLQDEDREYGYVIERGNKFVGAVSIDSLKTALT
                     QQQGLDAALIDAPLAVDAQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRAL
                     DREGVNNG"
     gene            7298..8362
                     /gene="proW"
                     /locus_tag="ACHY1N_004062"
     CDS             7298..8362
                     /gene="proW"
                     /locus_tag="ACHY1N_004062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HFS4046271.1"
                     /translation="MADQNNPWDTTPAADSAAQSADAWGTPATAPTDGGGADWLTSTP
                     APNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFRPVFQGVRVPVDYILNGFQQLLL
                     GMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCI
                     VIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLLTRPFIK"
     gene            8420..9412
                     /gene="proX"
                     /locus_tag="ACHY1N_004063"
     CDS             8420..9412
                     /gene="proX"
                     /locus_tag="ACHY1N_004063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HFS4046272.1"
                     /translation="MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDATFTAVNWTPLHDNMYEAAGGDKK
                     FYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPG
                     WGCEGAINHQLAAYELTHTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNEL
                     KPGKDVVWLQVPFSALPGDKNADTKLPNGANYGFPVSTMHIVANKAWAEKNPAAAKLF
                     AIMQLPVADINAQNAIMHDGKASEGDIQGHVDGWIKAHQQQFDGWVNEALAAQK"
     gene            9704..10888
                     /locus_tag="ACHY1N_004064"
     CDS             9704..10888
                     /locus_tag="ACHY1N_004064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4046273.1"
                     /translation="MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMM
                     ILGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANL
                     GGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISDKILRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKS
                     HHTTTFGLLLLLLSWLAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEA
                     AN"
     gene            11012..11749
                     /gene="ygaZ"
                     /locus_tag="ACHY1N_004065"
     CDS             11012..11749
                     /gene="ygaZ"
                     /locus_tag="ACHY1N_004065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine exporter subunit YgaZ"
                     /protein_id="HFS4046274.1"
                     /translation="MESPTPQPAPGSATFMEGCKDSLPIVISYIPVAFAFGLNATRLG
                     FSPLESVFFSCIIYAGASQFVITAMLAAGSSLWIAALTVMAMDVRHVLYGPSLRSRII
                     QRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGA
                     FSGSGLLQGYPAVEAALGFMLPALFMSFLLASFQRKQSLCVTAALVGALAGVTLFSIP
                     VAILAGIVCGCLTALIQAFWQGAPDEL"
     gene            11739..12074
                     /gene="ygaH"
                     /locus_tag="ACHY1N_004066"
     CDS             11739..12074
                     /gene="ygaH"
                     /locus_tag="ACHY1N_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine transporter subunit YgaH"
                     /protein_id="HFS4046275.1"
                     /translation="MSYEVLLLGLLVGAANYCFRYLPLRLRVGNARPTKRGAVGILLG
                     TIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVLGASFYKTRSIIIPTLLSALAYG
                     LAWKVMAII"
     gene            12165..12695
                     /gene="emrR"
                     /locus_tag="ACHY1N_004067"
     CDS             12165..12695
                     /gene="emrR"
                     /locus_tag="ACHY1N_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter EmrAB
                     transcriptional repressor EmrR"
                     /protein_id="HFS4046276.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHLLWSALSTTEKDQLEQITRKLLS
                     RLDQMEQDGVVLEAMS"
     gene            12822..13994
                     /gene="emrA"
                     /locus_tag="ACHY1N_004068"
     CDS             12822..13994
                     /gene="emrA"
                     /locus_tag="ACHY1N_004068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HFS4046277.1"
                     /translation="MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFL
                     VLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFE
                     KAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREEL
                     QHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRI
                     VSPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYP
                     LRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG"
     gene            14011..15549
                     /gene="emrB"
                     /locus_tag="ACHY1N_004069"
     CDS             14011..15549
                     /gene="emrB"
                     /locus_tag="ACHY1N_004069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HFS4046278.1"
                     /translation="MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSL
                     NMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQI
                     MLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESMHHAQLTESVNPFNPNAQAMYSQL
                     EGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            complement(15613..16128)
                     /gene="luxS"
                     /locus_tag="ACHY1N_004070"
     CDS             complement(15613..16128)
                     /gene="luxS"
                     /locus_tag="ACHY1N_004070"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFS4046279.1"
                     /translation="MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPN
                     KEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
                     LPEEKLQELHI"
     gene            complement(16278..17834)
                     /gene="gshA"
                     /locus_tag="ACHY1N_004071"
     CDS             complement(16278..17834)
                     /gene="gshA"
                     /locus_tag="ACHY1N_004071"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HFS4046280.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPF
                     EKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAK
                     IGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLG
                     IGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
                     ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTE
                     PFAVWLEKHA"
     gene            complement(17907..18335)
                     /locus_tag="ACHY1N_004072"
     CDS             complement(17907..18335)
                     /locus_tag="ACHY1N_004072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqaA family protein"
                     /protein_id="HFS4046281.1"
                     /translation="MSEALSLFSLFASSFLSATLLPGNSEVVLVAMLLSGISHPWVLV
                     LTATMGNSLGGLTNVILGRFFPLRKTSRWQEKATGWLKRYGAVTLLLSWMPVVGDLLC
                     LLAGWMRISWGPVIFFLCLGKALRYVAVAAATVQGMMWWH"
     gene            complement(18332..18898)
                     /gene="yqaB"
                     /locus_tag="ACHY1N_004073"
     CDS             complement(18332..18898)
                     /gene="yqaB"
                     /locus_tag="ACHY1N_004073"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HFS4046282.1"
                     /translation="MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMI
                     ALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGR
                     RPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
                     QCVVFEDADFGIQAARAAGMDAVDVRLL"
     gene            complement(19179..19255)
                     /locus_tag="ACHY1N_004074"
     tRNA            complement(19179..19255)
                     /locus_tag="ACHY1N_004074"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19219..19221),aa:Arg,seq:acg)
BASE COUNT         4616 a         5008 c         4882 g         4862 t
ORIGIN      
        1 tcgctaattc cgcaagcctg acaaaaccga agtgaataaa aatgcaatat aacagaataa
       61 aagaaaacac ccctcactgg tgctttctgc tgttaatgta cattttctgg cataaaaaat
      121 actgtaaatg acacggtcac gacatacacc gaattctcta cgcttatagc gttacctcac
      181 ccccaaactt tcattagtga aattaaagga aaggtcatat ctaattgatt taattgaaaa
      241 taaatcatat cggcatgtaa aaatccacaa tgtacaaaaa acgagccgtt acggaatatt
      301 ttatctacaa aaactgacta aataaaaatt tttcactaat tgaatagtca tagccagcga
      361 tatacgctat gcgaaaatgc agatggcaat gagatccact gctttcatct ccattaacat
      421 cccattacgc ttttattaag gagcattagc atgttctcac cgcagtcacg cttgcgtcat
      481 gcagttgcag atacgttcgc gatggttgtt tactgttctg tcgtgaacat gtgtattgaa
      541 gttttcctct ccggaatgag cttcgaacag tctttttatt ccagattggt agcgattccg
      601 gtgaacatct taattgcatg gccatacggt atgtaccgcg atctgtttat gcgcgcggca
      661 cgcaaagtta gcccgtcggg ctggataaaa aatctggctg atatcctggc ttatgtgacg
      721 ttccagtcac cggtgtatgt ggcgatcttg ttagtggtgg gcgcagactg gcatcagatt
      781 atggcggcgg tcagttcaaa catcgttgtt tcgatgttga tgggggcggt ttatggctac
      841 ttcctcgatt attgccgccg actgtttaaa gtcagccgtt accagcaggt aaaagcctga
      901 ctcttctttt cgcgactggc atcgccagtc gcgtctttaa ctggcttcgc caaataaacc
      961 attcaaataa cgttcaagcg caacacgcga actaaagcca tgcgggatac cgtaatgctc
     1021 gtgtcgctcg cctgctaaat agagcggaaa ttgctggtaa tgatcgcaag ttttaatatc
     1081 ggaagcgggt tcagccagtg ttgaactgcg ttcttttaat gttggatgaa ttaccagagc
     1141 ggtacgtccc attcgcgctt cgcgattaac atagacataa ttttccccac ggcggtaacc
     1201 atacgctttc tgggttacca catcgacagt aaaaccgact ttttcaagta cgcgcgccac
     1261 ctcgtctggt cgtaaataca tatttgatcc tcgttattat caaccgcggg cctaccttac
     1321 ctgattgcgc attcacaacg ctttcagaaa agtccataaa gccgcgatga acctcagtta
     1381 agaaaattat ggtctacact gaaaattaca tcgaattcta atgggggatc atatgtttaa
     1441 ccgaccgaac cgcaacgacg ttgatgatgg cgtgcaggat atccagaatg atgtcaatca
     1501 attagctgac agcctcgaat ctgtattgaa gtcctggggc agcgacgcca aaggggaagc
     1561 tgaagccgca cgcagtaaag ctcaggcatt gctgaaagaa accagggcgc gaatgcatgg
     1621 tcgtactcgc gtccagcaag ccgcacgcga tgccgttggc tgcgcggatt cttttgttcg
     1681 tgaaagaccc tggtgtagcg tgggtacagc agctgcggta ggtattttta tcggcgcact
     1741 gttaagcatg cgcaaatcgt agtgcaaaaa tgataataaa tacgcgtctt tgaccccgaa
     1801 gcctggcttc ggggtttctt tttgcctggt gaatcacaaa aatcccccta ccccgtcacg
     1861 ctcatatcca gggtaatttc gaccactatt tgctatatat tgtgtggttg aatctttttt
     1921 caactacatc tagtatctct gtatcaacag agatacaacc cgacgcgtat catcgcgccg
     1981 tatcttcatt ttaaacggaa atacgaatca tgcgcattac tatttacact cgtaacgatt
     2041 gcgttcagtg ccacgccacc aaacgggcga tggaaaaccg gggctttgat tttgaaatga
     2101 ttaatgtcga tcgcgttcct gaagcagcgg aagcgttgcg tgctcagggc tttcgtcagt
     2161 tgccggtagt gattgctggc gatcttagct ggtctggttt ccgtccggac atgattaacc
     2221 gtctgcatcc agcgccacac gcggccagtg catgagccag ctcgtctact tctccagcag
     2281 ctccgaaaac acgcagcgtt ttatcgaacg tttaggtctg cccgcggtgc gcatcccgct
     2341 caatgagcgg gaacggattc aggtagacga gccttacatc ctgatcgtgc cctcttacgg
     2401 cggcggcggt acggctggcg cggtgccacg acaggtaatt cgctttttaa acgacgagca
     2461 caaccgggcg ttgcttcgcg gcgttattgc ttctggtaat cgcaactttg gtgaggcgta
     2521 tggccgcgcc ggagatgtga ttgcccggaa atgcggcgtg ccgtggctgt accgttttga
     2581 actcatgggt acgcaaagcg atatcgaaaa cgttcgtaaa ggagtaaccg aattttggca
     2641 acgacaaccg cagaatgcct gacgcaggaa acgatggatt accacgcgct gaatgcgatg
     2701 cttaacctct acgatagcgc aggtcgcatt cagttcgata aagaccgcca ggccgttgac
     2761 gcctttattg cgacgcatgt gcgtccgaac agtgtgacct tcagtagcca gcagcagcgc
     2821 ctgaactggc tggtcaacga aggttactat gatgaaagcg ttcttaatcg ctactctcgc
     2881 gactttgtca ttacgctgtt tgcccacgca cacaccagcg gttttcgttt ccagacattc
     2941 ctcggggcat ggaagtttta caccagctat acgttgaaga cattcgacgg taaacgttat
     3001 ctggaagatt ttgccgatcg agtcacgatg gtggcgctga cgctggcaca aggcgatgcg
     3061 acgctggcgt tgcaactgac cgatgaaatg ctgtcaggac gctttcagcc agccacgcca
     3121 acattcctca actgcggtaa gcagcagcgc ggcgaactgg tttcctgttt tctgctgcgt
     3181 attgaagaca atatggagtc gattggccgg gcggtaaatt ccgcactgca actgtcgaaa
     3241 cgcggcggcg gcgtggcatt tttgctgtcg aatctgcggg aagcgggcgc gccaattaaa
     3301 cgtattgaaa atcaatcttc tggcgtgatt ccggtgatga aaatgctgga agacgcattt
     3361 tcctatgcca accagctcgg cgctcgtcag ggggctggtg cagtctattt acatgcccat
     3421 catcccgata ttctgcgttt tctcgatacg aaacgggaaa atgccgacga gaaaatccgc
     3481 attaaaacac tgtcgctggg cgtggtgctc ccggatatca ctttccatct ggcaaaagag
     3541 aatgcgcaga tggcgctgtt ttcgccttat gacgtagagc gagtttatgg caagccgttt
     3601 gccgatgtgg ccatcagcca acactatgac gaactggttg ccgatgaacg cattcgcaaa
     3661 aaatacctca acgcccgtga tttcttccag cgactggcag aaatccagtt tgagtccggc
     3721 tatccctaca tcatgtatga agacacggta aaccgtgcta accctatcgc cgggcgcata
     3781 aatatgagta atctctgctc agaaattttg caggttaaca gcgcctcaga gtatgacgag
     3841 aatctcgact atgcccgtac aggccatgat atttcctgca atttaggttc gttgaatatt
     3901 gcccacacca tggattcccc caactttgcc cgcacggtag agactgccgt acgcggttta
     3961 acggcggtgt cagatatgag tcatatccgc agcgtgccgt ccatcgaagc cggaaatgcc
     4021 gcctcacacg ccatcgggct ggggcagatg aatttacacg gttatctggc gcgagaaggc
     4081 atcgcttatg gttcgccgga agcactggat ttcaccaatc tctatttcta taccatcacc
     4141 tggcacgcac tgcgtacctc gatgttgctg gcacgcgaac gcggtgaaac cttcgccggg
     4201 ttcaaacagt cacgttatgc cagtggtgaa tatttcagcc aatatctgca aggtaactgg
     4261 cagccgaaaa cggcgaaagt tggcgaactg tttgcccgca gcggtattac gttacctacc
     4321 cgtgagatgt gggcgcaact gcgcgacgac gtgatgcgct acggcattta taaccagaat
     4381 cttcaggcgg tgccgccaac cggttctatc tcttatatca accatgctac gtcgagtatt
     4441 catccgattg tggcgaaagt agagatacgc aaagagggca aaacaggacg cgtttactac
     4501 cctgccccgt ttatgactaa cgagaatctg gcgctgtatc aggatgctta cgaaatcggc
     4561 gcagaaaaga tcatcgacac ctacgcggaa gcgactcgcc atgtcgatca gggtttgtcg
     4621 ctgacgctgt ttttccccga taccgccacc actcgcgata tcaacaaagc gcagatttac
     4681 gcctggcgca aaggtatcaa aacgctctat tacattcgcc tgcgtcagat ggcgctggaa
     4741 ggcactgaaa ttgaaggctg cgtctcctgt gcactttaag gaatatctat gaaactctca
     4801 cgtatcagcg ccatcaactg gaacaagata tctgacgata aagatctgga ggtgtggaat
     4861 cgcctgacca gcaatttctg gctaccagaa aaggtgccgc tgtcgaacga tattcctgcc
     4921 tggcagacat taactgtcgt agaacaacaa ctgacgatgc gcgtttttac tggcctgacg
     4981 ctgctcgaca cgctgcaaaa tgttatcggc gcgccttcgc tgatgcccga tgcactcacg
     5041 cctcatgaag aagcggtatt atcgaatatc agctttatgg aagcggttca tgcccgctct
     5101 tacagttcga ttttctcgac gctgtgtcag accaaagatg tcgatgccgc ctacgcctgg
     5161 agtgaagaaa acgcaccgtt gcagcgaaaa gctcagatta ttcagcaaca ttatcgcggt
     5221 gatgatccgc tgaaaaagaa aatcgccagt gtgtttcttg aatctttttt gttctattcc
     5281 ggtttctggc tgccgatgta tttttccagc cgcggaaagc tgaccaatac cgcagatctg
     5341 atccgtctga ttatccgcga tgaagcagtc cacggttact acataggcta taaatatcag
     5401 aaaaacatgg aaaagatatc tctgggacaa cgtgaagagt tgaagagttt cgccttcgat
     5461 ttattgctgg aactctacga caacgagttg caatacaccg atgagctgta cgccgaaacc
     5521 ccgtgggctg acgatgtgaa agcgtttctc tgttacaacg ccaataaggc tttgatgaat
     5581 ctgggctacg aaccgttatt tcccgcagaa atggcggaag tgaatccggc aatcctcgcc
     5641 gcgctttcgc cgaatgccga tgaaaatcac gatttctttt ccggttcagg ctcctcttat
     5701 gtgatgggga aagcggttga aacagaagat gaagactgga atttctgagg gtgttatttt
     5761 caaaaatatc actacccgca gcagggaaat aattcccgcc aaatagcttt ttatcacgca
     5821 aatattctgt agtgatctac actgatactc tgttgcatta ttcgcctgaa actacaatat
     5881 tcaggcgttt tttcgctatc tatgacaaaa aatatcaact tttctcgatt tgctctcagc
     5941 ccttatatca cgggaaattc cggcgatttg ctcgcatcaa tattcatgcc acatttgccc
     6001 tcaggggttg cctcagattc tcagtatgtt agggtagaaa aaagtgacta tttccattgg
     6061 gtaatatatc gacataaaca aataaaggaa tctttctatt gcatggcaat taaattagaa
     6121 attaaaaatc tttataaaat atttggtgag catccacagc gagcgttcaa atatatcgaa
     6181 caaggacttt cgaaagaaca aattctggaa aaaactgggc tatcgcttgg cgtaaaagac
     6241 gccagtctgg ccattgaaga aggcgagata tttgtcatca tgggattatc cggctcgggt
     6301 aaatccacaa tggtacgcct tctcaatcgc ctgattgaac ccacccgcgg gcaagtgctg
     6361 attgatggtg tggatattgc caaaatatcc gatgccgaac tccgtgaggt gcgcagaaaa
     6421 aagattgcga tggtcttcca gtcctttgcc ttaatgccgc atatgaccgt gctggacaat
     6481 actgcgttcg gtatggaatt ggccggaatt aatgccgaag aacgccggga aaaagccctt
     6541 gatgcactgc gtcaggtcgg gctggaaaat tatgcccaca gctacccgga tgaactctct
     6601 ggcgggatgc gtcaacgtgt gggattagcc cgcgcgttag cgattaatcc ggatatatta
     6661 ttaatggacg aagccttctc ggcgctcgat ccattaattc gcaccgagat gcaggatgag
     6721 ctggtaaaat tacaggcgaa acatcagcgc accattgtct ttatttccca cgatctcgat
     6781 gaagctatgc gtattggcga ccgaattgcc attatgcaaa atggtgaagt ggtacaggtc
     6841 ggcacaccgg atgaaattct caataatccg gcgaatgatt atgtccgtac cttcttccgt
     6901 ggcgttgata ttagtcaggt attcagtgcg aaagatattg cccgccggac accgaatggc
     6961 ttaattcgta aaacccctgg cttcggccca cgttcggcac tgaaattatt gcaggatgaa
     7021 gatcgcgaat atggctacgt tatcgaacgc ggtaataagt ttgtcggcgc agtctccatc
     7081 gattcgctta aaaccgcgtt aacgcagcag caaggtcttg atgcggcgct gattgatgcg
     7141 ccgttagcag tcgatgcaca aacgcctctt agcgagttgc tctctcatgt cggacaggca
     7201 ccctgtgcgg tgcccgtggt cgacgaggac caacagtatg tcggcatcat ttcgaaagga
     7261 atgctgctgc gcgctttaga tcgtgagggg gtaaataatg gctgatcaaa ataatccgtg
     7321 ggataccacg ccagcggcgg acagtgccgc gcaatccgca gacgcctggg gtacaccggc
     7381 gactgcaccg actgacggcg gtggtgctga ctggctgacc agtacgcctg cgccaaacgt
     7441 cgagcatttt aatattctcg atccgttcca taaaacgctg atcccgctcg acagttgggt
     7501 cactgaaggg atcgactggg ttgttaccca tttccgtccc gtcttccagg gcgtgcgcgt
     7561 tccggttgat tatatcctca acggtttcca gcagttgctg ctgggtatgc ccgcaccggt
     7621 ggcgattatc gttttcgctc tcatcgcctg gcagatttcc ggggtcggaa tgggcgtggc
     7681 gacgctggtt tcgctgattg ccatcggcgc aatcggtgcc tggtcgcagg caatggttac
     7741 tctggcgctg gtattaaccg ccctgctgtt ctgtatcgtc atcggtttgc cgttggggat
     7801 ctggctggcg agaagtccgc gagcggcgaa aattattcgt ccactgcttg atgccatgca
     7861 gaccacgcca gcgtttgttt atctggtgcc aatcgtcatg ctatttggta tcggtaacgt
     7921 gccgggcgtg gtggtgacga tcatctttgc tctgccgccg attatccgtc tgaccattct
     7981 ggggattaac caggttccgg cggatctgat tgaagcctcg cgctcattcg gtgccagccc
     8041 gcgccagatg ctgttcaaag ttcagttacc gctggcgatg ccgaccatta tggcgggcgt
     8101 taaccagacg ctgatgctgg ccctttctat ggtggtcatt gcctcgatga ttgccgtcgg
     8161 cgggctgggt cagatggtac ttcgcggtat cggtcgtctg gatatggggc ttgccaccgt
     8221 tggcggcgtc gggattgtga tcctcgccat tatcctcgat cgcctgacgc aggccgttgg
     8281 gcgcgactca cgcagtcgcg gcaaccgtcg ctggtacacc actggccctg ttggtctgct
     8341 gacccgccca ttcattaagt aactctgcac ttgcccggtg acgccgggca ttatcaccct
     8401 gccaaaaaaa ggaataacaa tgcgacatag cgtacttttt gcgacagcgt ttgccacgct
     8461 tatctctaca caaacttttg ctgccgatct gccgggcaaa ggtattactg ttaatccagt
     8521 tcaaagcacc atcaccgaag aaaccttcca gacgctgctg gtcagtcgtg cgctggagaa
     8581 attaggttat accgtcaaca aacccagcga agtggattac aacgttggct acacctcgct
     8641 tgcttccggc gatgcaacct tcaccgccgt gaactggacg ccactgcatg acaacatgta
     8701 cgaagctgcc ggtggcgata agaaatttta tcgtgaaggg gtatttgtta acggcgcggc
     8761 acagggttac ctgatcgata agaaaaccgc cgaccagtac aaaatcacca acatcgcaca
     8821 actgaaagat ccgaagatcg ccaaactgtt cgataccaac ggcgacggaa aagcggattt
     8881 aaccggttgt aaccctggct ggggctgcga aggtgcgatc aaccaccagc ttgccgcgta
     8941 tgaactgacc cataccgtga cgcataatca ggggaactac gcggcgatga tggccgacac
     9001 catcagtcgc tacaaagagg gcaaaccggt gttttactac acctggacgc cgtactgggt
     9061 gagtaacgaa ctgaagccgg gcaaagatgt cgtctggttg caggtgccgt tctccgcact
     9121 gccgggcgat aaaaacgccg ataccaaact gccgaatggt gcgaattatg gcttcccggt
     9181 cagcaccatg catatcgttg ccaacaaagc ctgggccgag aaaaacccgg cagcagcgaa
     9241 actgtttgcc attatgcagt tgccagtggc agatattaac gcccagaacg ccattatgca
     9301 tgacggcaaa gcctcagaag gcgatattca gggccacgtt gatggctgga tcaaagccca
     9361 ccagcagcag ttcgatggct gggtgaatga ggcgctggca gcgcagaagt aatttttatt
     9421 caggcggata aggcgttttt gcctcatccg ccgctctgta cacaatgcct gatgcgacgc
     9481 tgacgcgtct tatcatgcct acaaaataca ctcattccgt atggcggata aggcgttttc
     9541 gccgcatccg ccgttctgtg cacaatgcct gatgcgacgc tggcgcgtct tatcatgcct
     9601 acaaaccaca tcgcacattt caacaagcta tctttcatcc catattcatc aacatccgct
     9661 attattgatt tccagcttaa tcatcacctg atgaacaaaa ataatgacta aacctaatca
     9721 tgagcttagc ccggcgctga tcgtgctgat gtctatcgcc accggtctgg cggtcgccag
     9781 taactattac gctcagccat tgctcgacac catcgcgcgt aacttttccc tttccgccag
     9841 ttcggcaggc tttattgtta ccgccgcgca attgggctat gcagcaggtc tgctgtttct
     9901 tgttcccctc ggtgatatgt ttgaacgccg ccgcctgatt gtctcgatga ccttactggc
     9961 ggcaggcggc atgttaatca ctgccagcag tcagtcgctg gcgatgatga tcctcggtac
    10021 ggcattaacc ggtttattct ctgtcgtggc acaaattctg gttccgctgg cagcgacgct
    10081 ggcttcaccg gacaaacgcg gcaaagtggt tggcactatt atgagcggtc tgctgttggg
    10141 gatcttgctg gcacggacag ttgccggatt gctggcgaat ctcggcggct ggcgcaccgt
    10201 cttttgggtt gcttcggtgt taatggcact gatggcgctg gcattatggc gtggtctgcc
    10261 acaaatgaaa tcagaaaccc acctcaacta cccacagttg ttgggttccg ttttcagtat
    10321 gtttatcagc gataaaattc tgcgtacccg cgcgttgctg ggctgcctga cctttgccaa
    10381 tttcagcatt ctctggacct caatggcctt tttgcttgcc gctccacctt ttaactacag
    10441 cgatggtgta attggtctgt ttggacttgc gggagctgcc ggagcgttgg gcgctcgtcc
    10501 ggcgggcggt tttgccgata agggcaaatc gcaccacacc acaactttcg gtctgctgct
    10561 gctattactt tcatggctgg cgatctggtt tggtcacact tccgtactgg cgttgattat
    10621 cggaatcctg gtgctggatc tcaccgtgca gggcgtgcat atcactaacc agacggtaat
    10681 ttatcggata catcctgatg cgcgcaatcg cctgaccgca ggttacatga ctagctactt
    10741 tattggcggt gccgccggtt cgctaatttc agcctcagcc tggcaacatg gcggttgggc
    10801 tggcgtttgt ctggctggcg cgacgattgc cctggttaac ttactggtct ggtggcgagg
    10861 ttttcatcgt caggaagccg caaattaagc aatcagcaac cgttttcgtg gctttacact
    10921 tataagggtg ttaagaagcc catcagtctg ataaggttaa gatattcatt cagtctattt
    10981 ataatattaa caatcgttaa gcgtacactc tatggaaagc cctactccac agcctgctcc
    11041 tggttcggcg accttcatgg aaggatgcaa agacagttta ccgattgtta ttagttatat
    11101 tccggtggcc tttgcgttcg gtctgaatgc gacccgtctg ggattctctc ctctcgaaag
    11161 cgtttttttc tcctgcatca tttatgcagg cgcgagccag ttcgtcatta ccgcgatgct
    11221 ggcagccggg agtagtttgt ggattgctgc actgaccgtc atggcaatgg atgttcgcca
    11281 tgtgttgtat ggcccgtcac tgcgtagccg tattattcag cgtctgcaaa aatcgaaaac
    11341 cgccctgtgg gcgtttggcc tgacggatga ggtttttgcc gccgcaaccg caaaactggt
    11401 acgcaataat cgccgctgga gcgagaactg gatgatcggc attgccttca gttcatggtc
    11461 atcgtgggta tttggtacgg taataggggc attctccggc agcggcttgc tgcaaggtta
    11521 tcccgccgtt gaagctgcat taggttttat gcttccggca ctctttatga gtttcctgct
    11581 cgcctctttc cagcgcaaac aatctctttg cgttaccgca gcgttagttg gtgcccttgc
    11641 aggcgtaacg ctattttcta ttcccgtcgc cattctggca ggcattgtct gtggctgcct
    11701 cactgcgtta atccaggcat tctggcaagg agcgcccgat gagctatgag gttctactgc
    11761 ttgggttact ggttggcgcg gcgaattatt gcttccgcta tttgccgctg cgcctgcgtg
    11821 tgggtaatgc ccgcccaacc aaacgtggcg cggtaggtat tttgctcggc accattggca
    11881 tcgcctcgat atgcgctctg ctggttgtct ctaccgcacc agaagtaatg cacgatacac
    11941 gccgtttcgt gcccacgctg gtcggcttcg cggtactggg tgccagtttc tataaaacac
    12001 gcagcattat catcccaaca ctgcttagtg cgctggccta tgggctcgcc tggaaagtga
    12061 tggcgattat ataacccaca agaatcattt ttctaaaaca atacatttac tttatttgtc
    12121 actgtcgtta ctatatcggc tgaaattaat gaggtcatac ccaaatggat agttcgttta
    12181 cgcccattga acaaatgcta aaatttcgcg ccagccgcca cgaagatttt ccttatcagg
    12241 agatccttct gactcgtctt tgcatgcaca tgcaaagcaa gctgctggag aaccgcaata
    12301 aaatgctgaa ggctcagggg attaacgaga cgttgtttat ggcgttgatt acgctggagt
    12361 ctcaggaaaa ccacagtatt cagccttctg aattaagttg tgctcttggg tcatcccgta
    12421 ccaacgcgac gcgtattgcc gatgaactgg aaaaacgcgg ttggatcgaa cgtcgtgaaa
    12481 gcgataacga tcgccgctgc ctgcatctgc aattaacgga aaaaggtcac gagtttttgc
    12541 gcgaggtttt accaccgcag cataactgcc tgcatctact ctggtccgcg ctcagcacaa
    12601 cagaaaaaga tcagctcgag caaatcaccc gcaaattgct ctcccgtctc gaccagatgg
    12661 aacaagacgg tgtggttctc gaagcgatga gctaacgcgt catctcgctc aaaaatccag
    12721 acttataaaa gaaaaaatga ctggccagca tcgcaacatg ctggcctttt tggcaagcag
    12781 gtcggctcag ccgatgagtt aagaagatcg tggagaacaa tatgagcgca aatgcggaga
    12841 ctcaaacccc gcagcaaccg gtaaagaaga gcggcaaacg taagcgtctg ctcctccttc
    12901 tcaccttgct ctttataatt attgccgtag cgatagggat ttattggttt ttggtactgc
    12961 gtcatttcga agaaaccgat gacgcatacg tggcagggaa tcaaattcaa attatgtctc
    13021 aggtgtctgg cagcgtgacg aaagtctggg ccgataacac cgattttgta aaagaaggcg
    13081 acgtgctggt cactctcgac ccgacagatg ctcgccaggc gtttgaaaaa gccaaaactg
    13141 cactggcttc cagcgttcgc caaacccacc agctgatgat taacagcaaa cagttgcagg
    13201 cgaatattga ggtgcagaaa atcgccctcg caaaagcaca aagcgactac aaccgccgtg
    13261 tgccgctggg caatgccaac ctgattggtc gcgaagagct gcaacacgcc cgcgacgccg
    13321 tcaccagtgc ccaggcgcaa ctggacgtcg ctattcaaca atacaatgcc aatcaggcga
    13381 tgattctggg gactaaactg gaagatcagc ctgccgtgca acaggctgcc accgaagtac
    13441 gtaacgcctg gctggcgctg gagcgtaccc gtattgtcag tccgatgacc ggttatgtct
    13501 cccgccgcgc ggtacagcct ggggcgcaaa ttagcccaac gacgccgctg atggcggtcg
    13561 ttccagccac caatatgtgg gtggatgcca actttaaaga gacgcagatt gccaatatgc
    13621 gtatcggtca gccggtcact atcaccacgg atatttacgg cgatgatgtg aaatacaccg
    13681 gtaaagtggt tggtctggat atgggcacag gtagcgcatt ctcactgctt ccggcgcaaa
    13741 atgcgaccgg taactggatc aaagtcgttc agcgtctacc tgtgcgtatc gaactggacc
    13801 agaaacagct ggagcaatac ccgctgcgca ttggtttgtc cacgctggtg agcgtcaata
    13861 ccactaaccg tgacggtcag gtactggcaa ataaagtacg ttcaacaccg gtcgcggtaa
    13921 gtaccgcgcg tgaaatcagc ctagcacctg tcaataaact gatcgacgat atcgtaaaag
    13981 ctaacgctgg ctaatccaga ggtgcgtgtg atgcaacagc aaaaaccgct ggaaggcgcg
    14041 caactggtca ttatgacgat tgcgctgtca ctggcgacat tcatgcaggt gctggactcc
    14101 accattgcta acgtggcgat ccccactatc gccgggaatc tgggctcatc gctcagccag
    14161 ggaacgtggg taatcacttc tttcggggtg gcgaatgcca tctcgatccc gcttaccggc
    14221 tggctggcaa agcgcgtcgg ggaagtgaaa ctgttccttt ggtccaccat cgcctttgct
    14281 attgcgtcgt gggcgtgtgg tgtctccagc agcctgaata tgctgatctt cttccgcgtg
    14341 attcagggga ttgtcgccgg gccgttgatc ccgctttcgc aaagtctatt gctgaataac
    14401 tacccgccag ccaaacgctc gatcgcactg gcgttgtggt cgatgacggt gattgtcgcg
    14461 ccaatttgcg gcccgatcct cggcggttat atcagcgata attaccactg gggctggata
    14521 ttcttcatca acgtgccgat tggcgtggcg gtggtgttga tgacactgca aactctgcgc
    14581 ggacgtgaaa cccgcaccga acggcggcgg attgatgccg tggggctggc actgctggtt
    14641 attggtatcg gcagcctgca gattatgctc gaccgcggta aagagctgga ctggttttca
    14701 tcacaggaaa ttatcattct taccgtggtg gcggtggtgg ctatctgctt cctgattgtc
    14761 tgggagctga ccgacgataa cccgatagtc gatctgtcgt tgtttaagtc gcgcaacttc
    14821 accatcggct gcttgtgtat cagcctcgcg tatatgctct acttcggcgc tattgttctg
    14881 ctgccgcagt tgttgcagga ggtctacggt tacacggcga cctgggcagg tttggcctct
    14941 gcgccggtag ggattattcc ggtgatcctg tcgccgatta tcggccgctt cgcgcataaa
    15001 ctggatatgc ggcggctggt aaccttcagc tttattatgt atgccgtctg cttctactgg
    15061 cgtgcctata cctttgaacc aggtatggat tttggcgcgt cggcctggcc gcagtttatc
    15121 caggggtttg cggtggcctg cttctttatg ccgctgacca ccattacgct gtctggtttg
    15181 ccaccggaac gactggcggc ggcatcgagc ctctccaact ttacgcgtac gctggcgggg
    15241 tctatcggca cgtccatcac caccaccatg tggaccaacc gcgagtcgat gcaccacgca
    15301 cagttaaccg agtcggtaaa cccgtttaac ccaaacgccc aggcgatgta cagtcaactg
    15361 gaagggcttg ggatgacgca acagcaggcc tccggctgga ttgcccagca gatcaccaac
    15421 caggggctga ttatttccgc caatgagatc ttctggatgt cagccgggat attcctcgtc
    15481 ctgctggggc tggtgtggtt tgctaaaccg ccatttggcg caggtggcgg cggaggcggt
    15541 gcgcactaag tacaactaag ccagttcatt tgaactggct tttttcaatt aattgtgaag
    15601 atagtttact gactaaatgt gcagttcctg caacttctct tccggcagcg ccagttcttc
    15661 gttgctgttg atgcgcacgt cacgttccag aatgctacgc gcaatatcct gcgcttcctg
    15721 caacgagtgc atctggtaag tgccacactg gtagacgttc agttccggga tctgattctg
    15781 atcctgcact ttcagcacgt cttccattgc cgctttccag gcatcagcaa cacgctgctc
    15841 atctggcgta ccaatcagac tcatataaaa accggtgcgg cagcccattg gcgagatatc
    15901 gataatctct acaccattac cgttaagatg gttacgcata aaaccagcaa acaggtgctc
    15961 cagggtatgg atccctcttt ctggcatcac ttctttgttc ggcacgcaga agcgcagatc
    16021 gaacacggtg attgcgtcgc catgcggggt gttcattgtt ttcgccaccc gaactgcagg
    16081 cgcttccatc cgggtatgat cgactgtgaa gctatctaac aacggcattt agccacctcc
    16141 ggtaattttt ttaaaaattt tctgaactct ttcttcccag gcgagtctga gtatatgaaa
    16201 gacgcgcatt tgttatcatc atccctgaat tcagagatga aattttggcc actcacgagt
    16261 ggcctttttc ttttctgtca ggcgtgtttt tccagccaca ccgcaaacgg ttcggtatca
    16321 gcggcttcca tttcctgctg acggcgttca gacgcctcgc gctcggctac aaaatcctct
    16381 tcgcgcagaa tttccagcgg ctcttcacgc agcagattac ggtaggcttc tgcaaatgct
    16441 ttgcctgttc cgccaatacc agtatcaatc atagacctta agatacgggc agagaaagtc
    16501 agatcgggat tatcgaagca ggcaaccagt tcatcacaca ctttctgata cgcttcgccg
    16561 ccgttaatac tatccagcgt ttgcgcgacg cgtttcagat cgcggaacag atctttaccc
    16621 acctgcggta acgggaactg tgcggtttcg cagccgatac ccagcgtcag acccggtttg
    16681 cgaccttcga ggatcacccg gttccagtta acgcgtgtac aggcaagttc gctactgctc
    16741 atttccggtg catcagccag cgcacaccag accataaaca ggtcgaggaa tcgcacctgc
    16801 tgttcatcta caccaatcgg cgagaacggg ttgatgtcca gcgaacgcac ttcaatatat
    16861 tcaatgccgc cacgtaacag cgcatcagaa ggcgactcgc cgctgcgggt aacgcgtttt
    16921 ggacgaatcg gcgcgtacag ttcgttttca atctgcaaca cgttgctgtt gatttgcagc
    16981 ctcttaccgt ctttctcaat accaatcttc gcgtactctt ccgatggcgt tttgattgcc
    17041 tgtttaaggc ccgctacgta ctcgtaaaga tcgttgaagg taataccaag attgctttgc
    17101 gatttattgg tatagccgag atcgctcaaa cgaagagagg tcgcatacgg caggtaatac
    17161 ataccgcact cggttttctc aaacggcagc gacgttggtt ttccttgcag gaaagaagaa
    17221 caaatcgccg gagatgcacc aaacagataa ggaatgaccc aaccgaaacg atagtaattg
    17281 cggataacgc ggaaatagcc cgcagaaatt ttctctttgg catcagcgcc cgagatatca
    17341 ccgcacttcg cttgccagaa tgccattggc aaagagaaat tgtagtgcac gccggaaatg
    17401 gtttgcatca gcgcgccgta gcgatttttc agcccttcac gatacagcgt tttaaagcgt
    17461 ccggtgttag aagtgccgta ctgtgccagt tcgatgtcct gaccttctgc gatgtagcat
    17521 ggcatactta acggccacat ccgctcatcg cccatattgc gcgccgtata acgatgcaga
    17581 tcgcgcataa aggtcagcat atgttcaata tcaccatcca ctggtgtaat gaattccagc
    17641 aatgcttccg caaaatcggt agtaatccat ttgtgcgtca gtgcggaacc taatgcttca
    17701 ggatgacctg ttgttgccag tgtgccatca gcattaacac gcaaagtttc gcgctccagc
    17761 ccacgctgta tcccctttaa cgcctgagga tgtttttcca gccaggccag cgcctgtgat
    17821 acgtccggga tcaaattgac ctcccgcctg tcaaaatcgt tttaattagc ataactgtaa
    17881 tggtgaccat atgtgcaggc ctacaattag tgccaccaca tcatgccctg aacggtcgct
    17941 gctgcaactg caacatagcg taacgcttta ccaaggcaca aaaaaaagat taccggtccc
    18001 cacgagatgc gcatccatcc cgctaacaga cacagtaaat cgccaaccac gggcatccag
    18061 cttaataata gcgtgactgc accatagcgt ttcagccagc cggtagcttt ctcttgccag
    18121 cgcgatgttt tacgcaatgg aaagaaacgc ccaaggataa cgttagttaa ccctccaagg
    18181 ctattaccca ttgttgctgt taaaactaaa acccagggat gactgatccc ggaaagcaac
    18241 attgccacca gcacgacttc ggagttgccg ggtaatagtg tagcgctgag aaaactactg
    18301 gcaaacaacg agaaaagcga taacgcttca ctcacagcaa gcgaacatcc acggcgtcca
    18361 tgcctgctgc acgggccgcc tgaataccga aatcggcatc ttcaaagacc acacactgcg
    18421 tcggttgcac gcccatacgc tgcgcgcaca acaaaaatgt gtctggcgcg ggtttatggt
    18481 gtttgacgtg atcagcagcg acgacggcgt caaaataacg gcgtaatccc aggtgcgcca
    18541 gcaatgcctc agcgatggcg ctttcactcc ccgttcctac agccattggg cgacgaccat
    18601 gccaactttt caccacttca acaagaggaa gcggctcgac actatccagc agcatacttc
    18661 ttactgcttc tgttttttca cgcgctaacg catgcgggtc gagatcggcc tgattcagct
    18721 caataattgc ctgagcaata cgccaggtgg gcgatccatt aagcgcaatc attgcctgaa
    18781 catcgtactg aagaccgtag tgccctaata cttcgcgcca cgctttacgg tgcgtaggct
    18841 ccgtatccag gattgtgcca tccatatcaa aaattaaacc tgcataacgc tcgtacatgg
    18901 tcttctcgca agtcgaaaaa tatgacgcta ctttagcgta attgcttgat tttgtcgctg
    18961 atggcgaagg agaagaaaat tcaggaaatg gataaagtag ttatttagaa atgagatatt
    19021 tttgaaggaa atttttggga gaagatggtg catccgggag gattactcac tggcgttcgc
    19081 ccttcgggcc gttgctgacg caacgttatc ctccctggtg cctgcggtta ataccgctat
    19141 ctcttcgata ccttcattgc tgaaggttac ggagaatatg gtgcatccgg gaggattcga
    19201 acctccgacc gctcggttcg tagccgagta ctctatccag ctgagctacg gatgcatcgg
    19261 gaaaatttat tttactgctg atattgatat cgctactaaa gccatatcaa gtaagagatg
    19321 gtgcatccgg gaggattact cgccttgcgg ctcgcccttc gggccgtt
//
LOCUS       DAZUDJ010000081        19253 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.081, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000081 DAZUDJ010000000
VERSION     DAZUDJ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19253
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.081"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..391)
                     /locus_tag="ACHY1N_004075"
     CDS             complement(<1..391)
                     /locus_tag="ACHY1N_004075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFS4046283.1"
                     /translation="MATLMEKDALLNGASQCITFLSNIIDNCSVSSHQDSGDALKRLV
                     SYRDYLYSTPAELVDFTQGKILLQQVRTQYQHEFNNTTHSENKASFDSIWQRLTNHEV
                     TPQQHPIGFVLGGQPGAGKSSLIELAKR"
     gene            complement(536..1885)
                     /gene="lysC"
                     /locus_tag="ACHY1N_004076"
     CDS             complement(536..1885)
                     /gene="lysC"
                     /locus_tag="ACHY1N_004076"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HFS4046284.1"
                     /translation="MSEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGLEPGERFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAA
                     ALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDVA
                     ALAELAALQLLPRLNDGLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVD
                     IWTDVPGIYTTDPRVVSAAKRIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPRAGGTLVCNKTENPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNDLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGEDAEQVVQKLHFNLFE"
     regulatory      complement(1977..2173)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            2410..4059
                     /gene="pgi"
                     /locus_tag="ACHY1N_004077"
     CDS             2410..4059
                     /gene="pgi"
                     /locus_tag="ACHY1N_004077"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFS4046285.1"
                     /translation="MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSAT
                     FGDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALR
                     NRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDL
                     GPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG"
     gene            4414..4656
                     /gene="yjbE"
                     /locus_tag="ACHY1N_004078"
     CDS             4414..4656
                     /gene="yjbE"
                     /locus_tag="ACHY1N_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide production protein YjbE"
                     /protein_id="HFS4046286.1"
                     /translation="MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSA
                     TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
     gene            4770..5408
                     /locus_tag="ACHY1N_004079"
     CDS             4770..5408
                     /locus_tag="ACHY1N_004079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418451.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HFS4046287.1"
                     /translation="MKRPALILICLLLQACSATTKELGNSLWDSLFGTPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFAEDGQQKWVTQDQATLVTQHGRLVKTLLGGDNLI
                     EVNNLAADPLIKPAQIVDGATWTRTMGWTEYQQVRYATARSVFKWDGTDTVKVGSDET
                     PVRVLDEEVSTDQARWHNRYWIDSEGQIRQSEQYLGADYFPVKTTLIKAAKQ"
     gene            5405..6142
                     /locus_tag="ACHY1N_004080"
     CDS             5405..6142
                     /locus_tag="ACHY1N_004080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC D2 domain-containing
                     protein"
                     /protein_id="HFS4046288.1"
                     /translation="MIKQTIVALILSVGASSVFAAGTVKVFSNGSSEAKTLTGAEYLI
                     DLVGQPRLANSWWPGAVISEELATAAASRQQQALLTRLAELAADSSADDAAAINALRQ
                     QIQALKVTGRQKINLDPDIVRVAERGNPPLQGNYTLWGGPPPSTVTLFGLISRPGKQP
                     FTPGRDVASYLSGQNLLSGADRSYAWVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVG
                     LADSVWSETPDALNADILQTLTQRIPQ"
     gene            6142..8238
                     /locus_tag="ACHY1N_004081"
     CDS             6142..8238
                     /locus_tag="ACHY1N_004081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HFS4046289.1"
                     /translation="MKKRHLLSLLALGISTACYGETYPAPIGPSQSDFGGVGLLQTPT
                     ARMAREGELSLNYRDNDQYRYYSASVQLFPWLETTLRYTDVRTRQYSSVEAFSGDQTY
                     KDKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGY
                     LGTSGNVKNPLCSASDKYCYRDNSYKQAGSIDGSQMFHGPASLFGGVEYQTPWQPLRL
                     KLEYEGNNYQQDFAGKLEQKSKFNVGAIYRVTDWADVNLSYERGNTFMFGVTLRTNFN
                     DLRPSYIDNARPQYQPQPQDAILQHSVVANQLTLLKYNAGLADPQIQAKGDTLYVTGE
                     QVKYRDSREGIIRANRIVMNDLPDGIKTIRVTENRLNMPQVTTETDVASLKNHLAGEP
                     LGHETTLAQKRVEPVVPQSTEQGWYIDKSRFDFHIDPVLNQSVGGPENFYMYQLGVMG
                     TADLWLTDHLLTTGSLFANLANNYDKFNYTNPPQDSHLPRVRTHVREYVQNDVYVNNL
                     QANYFQHLGNGFYGQVYGGYLETMFGGAGAEVLYRPLDSNWAFGLDANYVKQRDWRSA
                     KDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVV
                     GGYATITNVSKEEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGR
                     KFQLYDMTSDRSVNFR"
     gene            complement(8285..8563)
                     /locus_tag="ACHY1N_004082"
     CDS             complement(8285..8563)
                     /locus_tag="ACHY1N_004082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046290.1"
                     /translation="MKRNLIKVVKMKPYFAALMLSVSVLPAYAGPLGTADKADLPQSN
                     VSSPMMAQSLRQPDLQPISTDRKTECFRLYTPDRKPGVNCVPDGSTGH"
     gene            8579..8707
                     /locus_tag="ACHY1N_004083"
     CDS             8579..8707
                     /locus_tag="ACHY1N_004083"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046291.1"
                     /translation="MVDFSRIAGGWESPEWVIFELPALVRFVLPDAPPGAAYPAYG"
     gene            8833..9243
                     /gene="psiE"
                     /locus_tag="ACHY1N_004084"
     CDS             8833..9243
                     /gene="psiE"
                     /locus_tag="ACHY1N_004084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HFS4046292.1"
                     /translation="MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLAD
                     VLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLII
                     VDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE"
     gene            complement(9287..10762)
                     /gene="xylE"
                     /locus_tag="ACHY1N_004085"
     CDS             complement(9287..10762)
                     /gene="xylE"
                     /locus_tag="ACHY1N_004085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose transporter XylE"
                     /protein_id="HFS4046293.1"
                     /translation="MNTQYNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVA
                     PQNLNESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGS
                     AWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIR
                     GKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLY
                     TVPESPRWLMSRGKQEQAESILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVG
                     VIVIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIM
                     TVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCW
                     VLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGC
                     MGVLAALFMWKFVPETKGKTLEELEALWEPETKKTQQTATL"
     gene            complement(11134..12024)
                     /gene="malG"
                     /locus_tag="ACHY1N_004086"
     CDS             complement(11134..12024)
                     /gene="malG"
                     /locus_tag="ACHY1N_004086"
                     /EC_number="7.5.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HFS4046294.1"
                     /translation="MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNF
                     ATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITI
                     VFLLAQRWLVNGLTAGGVKG"
     gene            complement(12039..13583)
                     /gene="malF"
                     /locus_tag="ACHY1N_004087"
     CDS             complement(12039..13583)
                     /gene="malF"
                     /locus_tag="ACHY1N_004087"
                     /EC_number="7.5.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HFS4046295.1"
                     /translation="MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAI
                     TTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
                     ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGT
                     LTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKP
                     FLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            complement(13737..14927)
                     /gene="malE"
                     /locus_tag="ACHY1N_004088"
     CDS             complement(13737..14927)
                     /gene="malE"
                     /locus_tag="ACHY1N_004088"
                     /EC_number="7.5.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HFS4046296.1"
                     /translation="MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPA
                     LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGL
                     TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
                     KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYE
                     EELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQT
                     RITK"
     gene            15292..16407
                     /gene="malK"
                     /locus_tag="ACHY1N_004089"
     CDS             15292..16407
                     /gene="malK"
                     /locus_tag="ACHY1N_004089"
                     /EC_number="7.5.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HFS4046297.1"
                     /translation="MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQ
                     VGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDV
                     VLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV"
     gene            16479..17819
                     /gene="lamB"
                     /locus_tag="ACHY1N_004090"
     CDS             16479..17819
                     /gene="lamB"
                     /locus_tag="ACHY1N_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin LamB"
                     /protein_id="HFS4046298.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEAT
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVG
                     FGKLSLAVTRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDY
                     GRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSG
                     VAYVDEKFSYDINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVG
                     IRPMYKWTPIMSTLMEIGYDNVKSQRTGDTNNQYKITLAQQWQAGDSIWSRPAIRVFA
                     TYAKWDEKWGYDYTDKAKGTPNYGKAVPANFEGGSFGRGDSDEWTFGAQMEIWW"
     gene            18062..18982
                     /gene="malM"
                     /locus_tag="ACHY1N_004091"
     CDS             18062..18982
                     /gene="malM"
                     /locus_tag="ACHY1N_004091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HFS4046299.1"
                     /translation="MKMNKSLIALCLSAGLLASAPGISLADVNYVPQNTSDAPAIPSA
                     ALQQLTWTPVDQSKTQTTQLATGGQQLNVPGISGPVAAYSVPANIGELTLTLTSEVNK
                     QTSVFAPNVLILDQNMTPSAFFPSSYFTYQEPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTQLLDPAKAYAKGVGNSIPDIPDPVARHTSDGLLKLKVKTNSSSSVL
                     VGPLFGSSAPAPVTVGNTAAPAVAASAPAPVKKSEPMLNDTESYFNTAIKNAVAKGDV
                     DKALKLLDEAERLGSTSARSTFISSVKGKG"
BASE COUNT         4804 a         4927 c         4987 g         4535 t
ORIGIN      
        1 ctcttttggc taattcaatc agagatgatt tacctgctcc gggttgccca cctaaaacaa
       61 aaccaatggg atgctgttgc ggtgtgactt catgatttgt cagacgctgc caaatagaat
      121 caaaagatgc tttattttct gaatgcgtag tattgttgaa ttcatgctga tattgagttc
      181 ttacctgctg aaggagaatc ttaccttgtg taaaatcaac aagttcagcg ggggtagaat
      241 aaagataatc gcgatagctg actaatcgct tgagagcatc gcctgaatcc tgatgcgacg
      301 aaactgagca attatcaatg atatttgata aaaacgtgat gcactgactg gctccgttta
      361 aaagtgcatc tttttccatt aaagtagcca ttaacactcc tgttaaatga tatttttcgg
      421 tgattataat actgttctac aggagtgatt ttgcttttca gatattattt aatctatgtt
      481 ttcagtgagg atggcgtata acaatcggtg agcgttatac gccagtaggg aaatattact
      541 caaacaaatt aaaatgcagc ttctgcacca cctgctcggc atcttcgccg ggcaccagga
      601 agcacaggtt atggctggat gcgccgtaac aaatcatgcg aatgttgaac ggttccagta
      661 cgccgaatac ctctttgcca acgccgcagg cttttgacag gtcattgcca atcaacgcga
      721 ccagcgccag accttcttct acttccaccc ggcacagtgc ggaaagctcc atcagcagag
      781 attgcgtcag caacgtatcg ccagtggagg ttgaaccggt ggtatcaagg gttaatgcca
      841 cgctcacttc tgacgtggtg attaagtcta ccgaaatatt atgccgcgcg aggatgccga
      901 aaacttccgc gaggaagccg cgagaatgca gcatattcag gctgtgcaaa gtgagcagag
      961 tctgattgcg acgaagcgcc agcgcgcgga acagcggcgg attttcagtt ttattgcaca
     1021 ccagcgtacc acctgcgcgt gggtctttgc tggagccgac aaagactggg atatcgctgc
     1081 gtactgcggg tagcaacgtt gccggatgca gtacttttgc accaaaagtt gccatctctg
     1141 ccgcttcggc aaacgcgatt tcatcaatgc gttttgctgc ggaaactacg cgtggatcgg
     1201 tggtgtagat gcccgggacg tcggtccaga tatcaacacg agatgcgtgt aaagcctccg
     1261 ccagcaaggc tgccgtataa tcgctgcctc cacggccaag cgtcgttgta cgacctttat
     1321 tttcgctacc gataaatccc tgggtgatca ctaagccgtc attgaggcgt gggagcagct
     1381 gcagcgcggc cagttccgcc agcgcggcta catctggctc tgcacgacca aatcggtcgt
     1441 tggtacgcat cactttacgt acatcaaacc actgtgcctg aacatcgcgt tcgcgcagga
     1501 tttcgacaaa cagcagggtc gacatcagct cgccgtggct gaccagctca tctgtcagcg
     1561 ccggagacgt tgccagcgcc gccgcttctg ccagaacagt aatgttctcc agcagacgtt
     1621 caatctcttc acggataacg ttcgggtaac gcaaacgttc cagaatggca aactggatgt
     1681 tgcgaatagc gtcgagtttt tcgaatcgct cgccaggttc cagcccttcc gctaaagcga
     1741 ccagcagatt agtgatacca gcagaagccg agaggactac taaacgcacg ttggcatcag
     1801 aaagcacaat atcagcgctg cggttcatgg cgtcaaaatc agctacgctg gtaccgccaa
     1861 atttggagac aacaatttca gacataacta cctcgtgtca ggggatccat tttcagcctt
     1921 ggcacaaggg aagagcggaa gacgggtggg cgcagagcga tacttcgcta ctattttcac
     1981 ccagaagtgc tccaccactt gcgaaacgcc cgactgcgaa cgcttctggt gacaacccag
     2041 gggattcagc ccctgtagcc gatgatgaac gtggccagcc gttcaatcac ctcggcgatg
     2101 caccccctca ggtgttatca caggactggc tcctccaaca ccgttacttg ggcaacgcgc
     2161 ctcttctggc ctgcgctagc gcaggtagta catttataaa taaagggtga gcggggcggt
     2221 tgtcaacgac ggggtcatgc ggatttttca tccactcctg gcggtcagta gttcagctaa
     2281 taaatgcttc actgcgctaa gggtttacac tcaacattac gctaacggca ctaaaaccat
     2341 cacatttttc tgtgactggc gctacaatct tccaaagtca caattctcaa aatcagaaga
     2401 gtattgctaa tgaaaaacat caatccaacg cagaccgctg cctggcaggc actacagaaa
     2461 cacttcgatg aaatgaaaga cgttacgatc gccgatcttt ttgctaaaga cggcgatcgt
     2521 ttttctaagt tctccgcaac cttcggcgat cagatgctgg tggattactc caaaaaccgc
     2581 atcactgaag agacgctggc gaaattacaa gatctggcga aagagtgcga tctggcgggc
     2641 gcgattaagt cgatgttctc tggcgagaag atcaaccgca ctgaaaaccg cgctgtgctg
     2701 cacgtagcgc tgcgtaaccg tagcaatacc ccgattttgg ttgatggcaa agacgtaatg
     2761 ccggaagtca acgcggtgct ggagaagatg aaaaccttct cggaagcgat tatctccggt
     2821 gagtggaagg gttataccgg caaagcaatc actgacgtag tgaacatcgg gatcggcggt
     2881 tctgacctcg gcccgtacat ggtgaccgaa gcactgcgtc cgtacaaaaa tcacctgaac
     2941 atgcactttg tttctaacgt cgatgggact cacatcgcgg aagtgctgaa aaaagtaaac
     3001 ccggaaacca cgctgttcct ggtagcatct aaaaccttca ccactcagga aaccatgacc
     3061 aacgcccata gcgcgcgtga ctggttcctg aaagcggcag gtgatgaaaa acacgttgcg
     3121 aaacactttg cggcgctctc aaccaatgcc aaagccgttg gcgagtttgg tattgatact
     3181 gccaacatgt tcgagttctg ggactgggtc ggcggccgtt actctttgtg gtcagcgatt
     3241 ggcctgtcga ttgttctctc catcggcttt gataacttcg ttgaactgct ttctggcgca
     3301 cacgcgatgg acaagcattt ctccaccacg cctgccgaga aaaacctgcc tgtactgctg
     3361 gcgctgattg gcatctggta caacaatttc tttggtgcgg aaactgaggc gattctgccg
     3421 tatgaccagt atatgcaccg tttcgcggcg tacttccagc agggcaatat ggagtccaac
     3481 ggtaagtatg ttgaccgtaa cggtaacgtt gtggattacc agactggccc gattatctgg
     3541 ggtgaaccag gcactaacgg tcagcacgcg ttctaccagc tgatccacca gggaaccaaa
     3601 atggtaccgt gcgatttcat cgctccggct atcacccata acccgctctc tgatcatcac
     3661 cagaaactgc tgtctaactt cttcgcccag accgaagcgc tggcgtttgg taaatcccgc
     3721 gaagtggttg agcaggaata tcgtgatcag ggtaaagatc cggcaacgct tgactacgtg
     3781 gtgccgttca aagtgttcga aggtaaccgc ccgaccaact ccatcctgct gcgtgaaatc
     3841 actccgttca gcctgggtgc gttgattgcg ctgtatgagc acaaaatctt tactcagggc
     3901 gtgatcctga acatcttcac cttcgaccag tggggcgtgg agctgggtaa acaactggca
     3961 aaccgtattc tgccagagct gaaagatgat aaagaaatca gcagccacga tagctcgacc
     4021 aatggtctga ttaaccgcta taaagcgtgg cgcggttaat ttaaaaacct taataacaat
     4081 gccgacgtta tgtcggcatt gttttatcag ataaatcccc ttgtctgtga tttaacggaa
     4141 atcataccgt gaggttaatc ctaaaataga tttttaatcg tgattgattt cggaaaatac
     4201 tcagattaat tacttttact tttattttaa cattatgatt tttaatgtta tttatatata
     4261 agttgtagct tatatttgat attcattcca attatcctaa aaccccatct ctaattcccc
     4321 gcgccgtaat tcgcatgctt tagttgtgta tactcgatcc cgcccgaaat gtttttgggt
     4381 aaatctccat tcattcaatg aagggaaatt gttatgaaaa aagttctgta tggcattttt
     4441 gccatatctg cgcttgcggc gacttctgcg tgggctgcac ctgtacaggt gggcgaagcg
     4501 gcagggtcgg cagcaacgtc ggtttcggcg gggagttcct ccgcgaccag cgtcagcacc
     4561 gtaagctcgg cggtgggtgt cgcgctcgcg gcaaccggtg gcggtgatgg ttctaatacc
     4621 gggaccacca caaccacgac caccagtacc cagtaataaa gtatgtatcc ccaaaataat
     4681 ttgagtcatt gcatctgtgg cttgaagtat gaagggattt accataacca cactccggtg
     4741 tggttattct gcccctctgg agaagagtcg tgaagcgacc tgcactcatt cttatctgcc
     4801 tgctattaca ggcctgttca gccacgacta aagagctggg caattcactg tgggacagtc
     4861 tgttcggcac gccaggcgta cagctgacgg acgatgatat tcaaaatatg ccctacgcca
     4921 gccagtacat gcagcttaat ggcgggccgc aattgtttgt ggtgctggcc ttcgctgaag
     4981 acggacaaca aaaatgggtc actcaggatc aagccactct tgtcacacaa catggtcgtc
     5041 tggtgaagac tttgcttggc ggcgacaacc tgattgaagt gaataacctt gccgccgacc
     5101 cgctgattaa acccgcacaa attgttgatg gtgcaacatg gacgcgcacg atgggctgga
     5161 ccgagtacca gcaggtacgc tacgccaccg cacgctcagt cttcaaatgg gatggcaccg
     5221 ataccgtcaa ggtcggcagc gatgaaaccc cggttcgcgt gctggacgaa gaagtctcca
     5281 ccgaccaggc gcgctggcat aaccgctact ggatcgacag cgaagggcaa attcgccagt
     5341 cggaacagta tctcggcgcg gattatttcc cggtgaaaac cactctcatc aaggcggcaa
     5401 aacaatgatt aaacaaacta ttgtcgcatt gattttgagt gtgggggcgt catcggtctt
     5461 cgcggcggga accgtcaagg tattcagcaa tggcagcagt gaggccaaaa cgctgacggg
     5521 cgcagagtat ttaatcgatc tggtaggcca gccgcggctg gcaaacagtt ggtggcctgg
     5581 tgcggtgatt agcgaagagc tggcaacggc ggcagcatcg cggcagcagc aggcgttgct
     5641 gacacggctg gcagaactgg ctgcagattc cagcgccgac gatgccgccg cgattaacgc
     5701 cttacgccag caaattcagg cgttgaaagt gacgggcagg caaaaaatca atcttgatcc
     5761 tgatatcgtc cgcgttgccg aacgcggtaa cccaccgttg cagggcaact acacgctgtg
     5821 gggcgggcca ccaccgtcca cggtcacgct gttcgggctt atcagccgtc ctggcaagca
     5881 gccattcact ccaggtcgcg acgtggcgag ctatctctcc gggcagaacc tgcttagcgg
     5941 tgcggatcgc agctacgcgt gggtggttta cccggacgga cgcacgcaaa aagcgccggt
     6001 ggcttactgg aacaagcgtc acgtagagcc gatgcccggc agcattattt atgttggcct
     6061 cgcggactcc gtctggagtg agacgcctga tgcccttaac gccgacattc ttcagactct
     6121 gacgcagcgg ataccccaat aatgaaaaaa agacatctgc ttagcttact ggcgctgggc
     6181 attagcacag cttgctacgg cgaaacatat cctgcgccca ttggtccgtc gcagtcggat
     6241 ttcggtggcg taggattatt acaaacgccc accgcgcgca tggcgcggga aggggagttg
     6301 agcctgaact atcgagataa cgatcagtac cgttattact cagcttcagt gcaactcttc
     6361 ccgtggctgg aaacaacgct gcgctacacc gacgtgcgca cccggcagta cagcagcgtc
     6421 gaagcgttct ctggcgatca aacgtataaa gataaagcct tcgatctcaa actgcgtttg
     6481 tgggaagaga gttactggct gccgcaagtg gcggttggtg cgcgggatat cggcggtacg
     6541 gggctgtttg atgcggaata tcttgttgcc agcaaagcct gggggccgtt cgattttacg
     6601 ctcggcctgg gctggggata tctgggcacc agcggtaatg tgaaaaatcc gctctgttca
     6661 gccagtgata aatattgcta tcgcgataac agctacaaac aggcgggatc tatcgacggt
     6721 agccagatgt tccacggtcc tgcctcactg tttggcggcg tggaatacca gacgccctgg
     6781 caaccgctgc gcctgaaact ggagtatgaa ggcaataatt atcagcagga ttttgccggg
     6841 aagctggagc aaaaaagtaa gtttaacgtc ggtgcgattt atcgcgttac cgattgggcc
     6901 gacgttaacc ttagctatga acgtggcaac acctttatgt ttggcgtcac gctgcgcacc
     6961 aactttaacg atctgcgccc gtcctacatc gataacgccc gcccgcaata tcaaccgcag
     7021 ccgcaggatg ccattttgca gcattcggtg gtggcgaatc agttaacgct gttgaaatac
     7081 aatgccggac ttgccgatcc gcagatccag gcgaaaggcg atacgctgta tgttaccggc
     7141 gagcaggtga aatatcgtga ttcgcgcgaa gggatcatcc gtgctaatcg gatcgtgatg
     7201 aatgatctgc cggatgggat caaaacgatc cgcgttacgg aaaatcgcct taacatgccg
     7261 caggtgacga cggaaaccga tgtcgccagc ctgaaaaatc atctcgccgg agagccgttg
     7321 ggccacgaaa cgacgctggc gcaaaaacgc gtcgagccag tggttccgca gtccaccgag
     7381 cagggctggt atatcgacaa atcacgcttt gatttccata tcgatccggt gctgaaccag
     7441 tcggtcggtg gcccggaaaa cttttacatg tatcagctgg gcgtgatggg aacggcagat
     7501 ttgtggctga cggaccatct actgaccacc ggcagcctgt ttgcaaatct tgccaacaac
     7561 tacgacaagt ttaactacac caatccaccg caggactcgc acttaccgcg cgttcgtacc
     7621 catgtgcgcg agtatgtgca gaacgatgtc tatgtgaata acctgcaagc caactacttc
     7681 cagcatctgg gcaacggctt ctacggtcag gtctacggtg gttatctcga aaccatgttt
     7741 ggcggtgcgg gggcagaagt gttgtatcgc ccgctggaca gcaactgggc gtttggtctg
     7801 gatgccaact acgttaaaca gcgcgactgg cgtagtgcaa aagatatgat gaaattcacc
     7861 gactacagcg tgaaaaccgg acatctgacc gcctactgga cgccatcttt cgctcaggat
     7921 gtgttagtta aagccagcgt cgggcagtat ctggcagggg ataaaggcgg cacgctggag
     7981 atcgccaaac gctttgatag cggcgtggtg gtgggtggct atgccacgat cactaatgtt
     8041 tcaaaagagg agtacggcga aggggacttc accaaaggcg tgtatgtctc ggtaccgttg
     8101 gatctcttct cgtctggccc gacacgcagc cgtgcggcga ttggctggac gccgctgacg
     8161 cgtgacggtg gtcagcaact tgggcgtaag ttccagttgt atgacatgac cagcgaccgt
     8221 agcgtcaatt tccgctaagt catgggaaag gtgccagttt tcgcaatcac tggcaccctc
     8281 attcttaatg gcctgttgag ccatcaggaa cgcagttcac ccccggtttg cgatctggtg
     8341 tgtaaaggcg aaaacattct gtcttcctgt ccgtcgatat cggttgcaga tctggttgcc
     8401 tgagcgactg ggccatcatt gggctggaga cattgctttg cggtaggtcg gctttatcag
     8461 cagtaccgag cggaccagca taagcaggaa gaacagagac tgataacatc aaagcagcaa
     8521 aataaggctt catttttacc acctttatca ggttacgttt catttgttcc agaggaacat
     8581 ggtcgatttt tcgcgcattg ctggtggctg ggaatcacct gaatgggtga tttttgaatt
     8641 accggctttg gtgcggtttg tcttgccgga tgcgccgcca ggcgcggctt atccggccta
     8701 cgggtaggta tatccggctt tggtggaggc gcgctccaaa tccaggttga acaaaacata
     8761 cacaaaaaat atagatctcc gtcacatttt tgcgttatac aggaagctcg ccactgtgaa
     8821 ggaggtactg ctatgacgtc actctctcgt ccgcgcgtgg agtttatctc caccattttg
     8881 cagaccgtac tcaatcttgg cctgttgtgc ctcggcctga ttttggttgt cttcctcggc
     8941 aaagaaacgg tgcatctggc agatgtgctg ttcgcgccag aacaaaccag caaatatgag
     9001 ctggtagaag gactggtggt ttactttctc tatttcgaat ttatcgcgct gattgtgaaa
     9061 tactttcagt ccggttttca cttcccgcta cgttactttg tctatattgg gatcaccgcc
     9121 attgtgcgct tgatcatcgt cgatcataaa tcgccactgg atgtgttgat ctactcggct
     9181 gcgatcctgt tactggtgat cactctgtgg ttgtgtaatt cgaaacggct gaagcgggag
     9241 taaaaagaca gcacgccgaa ctggcgcggc gtgctggaca ggaagattac agcgtagcag
     9301 tttgttgtgt tttcttcgtt tccggttccc agagggcttc cagctcctca agggttttac
     9361 ctttggtttc cgggacaaat ttccacataa atagtgctgc cagaacgccc atacacccgt
     9421 aaatccagta ggagaaaccg ttgtggaaat gggccaccag ccaggagttt ttgtccatca
     9481 tcgggaaggt ccaggagacg aagtagttcg ccagccactg ggccgccacc gcgattgcca
     9541 gcgctttacc acgaatggca ttcgggaaga tttccgacag cagaacccag cataccggac
     9601 cccaggacat ggcaaaggcg gcaacataga acagcatcga cagtagcgcc acaatacccg
     9661 gtgcctgagt gtaaaacgcg gtaccgaggc taaacatacc gattgccatt ccgagcgcgc
     9721 cgataatttg cagtggctta cgaccaaatt tatccaccgt cataattgcc agaacggtga
     9781 aggtgaggtt gataactccg acaataatgg tctgcaacag cgcgatatcc gtgctggccc
     9841 ccagcgtttt gaacacttcc ggcgcgtagt acaacaccac attgatgccg acaaattgct
     9901 ggaagatgga gagcataacg ccgattacaa tcacgcccac gccaaacatc agcagacgac
     9961 caccggtttt gcggccatga tccagggagt gtttaatttc ctgtactgcc tgagttgcaa
    10021 gcgtgttgcc cataattttg cgcaggatac tttccgcctg ttcttgcttg ccgcgtgaca
    10081 tcagccagcg aggactttct ggcacggtat acagcagcat taagaacagc agtgcaggga
    10141 tacattccga ggcaaacata taacgccagc cgtcagtatt cagccagctg gcatcaccgg
    10201 aacgggcaat aaaatagttt acgcagtaaa ctaaaagttg cccgaaaata atcgcaaact
    10261 ggttaaatga aaccagtttc ccgcgaatat gagctggagc cagttccgca atatacattg
    10321 gtgaaagcat tgaggctaaa ccaacgccaa taccgccaat aatgcgataa ataacaaatt
    10381 ccgggacata acctgccaga taaacaggca ctgtgttgtc cgggtttata gaggtaaaac
    10441 caagttctgg ccaggcagaa cctacaccag aaataaaaaa caggacagca gcaatcttaa
    10501 gtgaatcacg acgaccgaag cggttactgc aataaccacc gagggcaccg ccgatgatgc
    10561 aaccaatcag agcgctggct acgcaaaacc ctaacaggga gttggcagcg gattcattta
    10621 agttttgtgg agcaacaaag acggtattga gtgactcaac agtaccggaa ataacggcgg
    10681 tgtcgtagcc aaataataaa ccacctaatg tagcgactaa ggtaatcgaa aatatataac
    10741 tggaattata ctgggtattc attcagacct gccttagatc attctgatct tttatcagtg
    10801 cattgatgtt ggaattgtca ggcagttaag gcaattatca ttttttacaa tgcgtttacg
    10861 taatgtcttt tctgtgatct taattgtgat aattatccaa aattgataaa aacaatacta
    10921 ttgccgtgat tcagagcacg aaagagaatt atcgtaagtg ggaaaacaaa taacgtaaaa
    10981 ataataagtt ctatgatggg aatattaacc ggcgaacgat tcagattgca gacgaaagaa
    11041 aaaaaggcgc tccgtggagc gccgaataat agtcacaagt tgggataacg taagttgagg
    11101 gtgcagcggc ataacattgg cagaacaaca tctttaacct ttcacaccac ctgccgtcag
    11161 gccgttgacc agccagcgtt gagccagcaa gaagacgatg gtgatcggta atgcagacat
    11221 cacggcagcg gcggcaaagt caccccacag gtagttttgc gggttgaggt attgctgcat
    11281 ccccacggcc agggtgtagc tatttacgtc acgcagtaac agcgacgcga ccggaacttc
    11341 agtaatggca gcgataaacg acaggatgaa caccaccgcc agaatcggta ctgacagcgg
    11401 caacaggaca aggcggaagg cctgccacgg tgtcgcacca tccagcgccg ccgcttcttc
    11461 cagcgaactg tcgatggttt cgaaatagcc tttgatggtc cagacatgca gcgcaatccc
    11521 acccagatac gcgaaaatta cgccgccatg agtattcaga ccaatgaatg gaatgtactc
    11581 acccagacga tcaaacaacg catacaacgc gaccagtgaa agtactgccg ggaacatctg
    11641 gaaaatcagc attcctttca gcagcgtcgc tttgcctgga aagcgcatac gggcgaaagc
    11701 gtaggcgcag gtggtggaga gcgccacaat gccaatcgcg gaaatcccgg cgacctttac
    11761 cgagttccac agccacagca gtaccgggaa tggcggtggc gtaatgcgac catcagcctg
    11821 ttcaacgcta aaacctaacg ccagtttcca gtgatcccag gagatttgct ccgggatcag
    11881 gctaccggtc gcgaagtttc cctgacgcag cgagatagcg acgaccatca gcagcgggaa
    11941 cataatcgcc gcgataaaaa gtagcagtag caggtgagta ataaacaaac gtgctttttg
    12001 cgatttcggt tggaccattg ccatttttgt tatctccctt aatcaaactt cattcgcgtg
    12061 gctttcaggt tcactatcgc cagcgcaccc accagcagga agatcagcgt ggcaattgct
    12121 gccgccagac cgaagtcctg acccccgccg ccttcaaaag cgatacggta ggtgtagtta
    12181 acaagcaggt cggtataacc ggctggcgtg gtcgtgccaa gacgatccgg gccgccgttg
    12241 gttaacagct gaatcagcac gaagttgtta aagttaaagg cgaagctggc gatcatcagc
    12301 ggcgtcagcg gtttaatcag cagcggcagc gtaatcttaa agaagttctg gaacggacct
    12361 gcgccatcca ttgctgaggc ttcatacaaa tcgtccggaa tcgctttcag caagcccatg
    12421 cagaggatca tcatgtacgg ataacccagc caggtattga cgataatcag catcgtgcgg
    12481 gcggtggtcg gatcgctgaa ccaggcgggc ttcacgccaa acagcgcgct caacatcatg
    12541 ttgatttcac cgaagctctg gttaaacaat cctttgaaaa tcaagattga aatgaacgat
    12601 ggcaccgcgt agggcagaat cagcaggacg cgatagaccg ctttgccgcg caacgcttcc
    12661 cactgcacca gacatgccag aaccatgccg accgccaccg ttaaaaagac agtgatcagc
    12721 gagaacacca cggtccagac gaaaatggcg aggaacggtt tctgaatgcc ttcgtcggta
    12781 aagacgcggg taaagttttt ccagccggtg gtcacggtgt aaccggggct tagcttttca
    12841 tcaccccagt tgccgtcggc ggtaatggac tggtaaaagc caatttggtt attcggacga
    12901 tatttcacgc cgctctgatt attcgtcaac gtgccgtcac cgtcgagtgt gtagagcggc
    12961 tgcgtgccag aaaactggcg cagggagctc atcatcactt tgttgccatc cggcagaatg
    13021 gcggtaatgt cactcagcgc ctgacgattc tgggtaatca cgcgcagatt cgcgcgttcg
    13081 ccttcgggct gggcggtcgt ttctttcagt tgcagttttt gctcgccgcc aaatttaaac
    13141 gcgtcggaga ggtaattttt gccggtttcg ccgtcgctga gcgccagttg ccactcatcg
    13201 cccgccgggt aaagaccaaa gttataggtt ttgcctgctt gccaggagcg atctaacaac
    13261 acttcctgcg cacgttcaaa agtcagctgg ttagtgctgc tgtagttggt gaaggcaatg
    13321 gcgatggtgc agaccagagg gaagaggacg aataatccca ttccagccat tcccgggtaa
    13381 acatagcgcc aggcgtaggc tttacgattg gcgaaaatat acagccccgc tgaactcaat
    13441 atcagcgtgg taatggcgaa caggtattcc ccttgtgcgt acattaaaac aacaaggtaa
    13501 cccaccagca ggccgagcag acctagcact gaccatttca gcgcgtcgct ttgccaccaa
    13561 tgtttctttt taatgacatc catggggttc ttcctcattc caggacggat aaggctttca
    13621 cgccttatcc gacaacaact gcctgatgcg acactgatgc gtcttatcag gcatacatgc
    13681 gtttcagttt tgtaggccgg acaaggcgtt cacgccgcat ccggcatttc acagcattac
    13741 ttggtgatac gagtctgcgc gtctttcagg gcttcatcga cagtctgacg accgctggcg
    13801 gcgttgatca ccgcagtacg cacggcatac cagaaagcgg acatctgcgg gatgttcggc
    13861 atgatttcac ctttctgggc gttttccatg gtggcggcaa tacgtggatc tttcgccaac
    13921 tcttcctcgt aagacttcag cgccactgca cccagcggtt tgtctttatt gaccgcttcc
    13981 agaccttcgt cagtcagcag atagttttcg aggaactctt tcgccagctc tttgttcgga
    14041 ctggcggcgt taataccggc gctcagcacg ccaacgaacg gtttagatgg ttgacccttg
    14101 aaggtcggca gtaccgttac accataattc actttgctgg tgtcgatgtt ggaccatgcc
    14161 cacgggccgt tgatggtcat cgctgtttcg cctttattaa aggcagcttc tgcgatggag
    14221 taatcggtgt ctgcattcat gtgtttgttt ttaataaggt caaccaggaa ggtcagaccc
    14281 gctttcgcgc cagcgttatc cacgcccacg tctttaatat cgtacttgcc gttttcatac
    14341 ttgaacgcat aacccccgtc agcagcaatc agcggccagg tgaagtacgg ttcttgcagg
    14401 ttgaacatca gcgcgctctt acctttcgct ttcagttctt tatccagcgc cgggatctct
    14461 tcccaggttt ttggtgggtt cggcagcaga tctttgttat aaatcagcga taacgcttca
    14521 acagcgatcg ggtaagcaat cagcttgccg ttgtaacgta cggcatccca ggtaaacgga
    14581 tacagcttgt cctggaacgc tttgtccggg gtgatttcag ccaacaggcc agattgagcg
    14641 tagccaccaa agcggtcgtg tgcccagaag ataatgtcag ggccatcgcc agttgccgca
    14701 acctgaggga atttctcttc cagtttatcc ggatgctcaa cggtgacttt aattccggta
    14761 tctttctcga atttcttacc gacttcagcg agaccgttat agcctttatc gccgttaatc
    14821 cagattacca gtttaccttc ttcgattttg gcgagagccg aggcggaaaa catcatcgtc
    14881 gttaatgcgg ataatgcgag gatgcgtgca cctgttttta ttttcataat ctatggtcct
    14941 tgttggtgaa gtgctcgtga aaacacctaa acggactcta gtttctttat acggcaacct
    15001 ctttccatcc tccttgcccc tacgccccac cgttgctttg tgtgatctct gttacagaat
    15061 tggcggtaat gtggagatgc gcacataaaa tcgccacgat ttttgcaagc aacatcacga
    15121 aattccttac atgacctcgg tttagttcac agaagccgtg ttctcatcct cccgcctcct
    15181 cccccataaa aaagccaggg ggtggaggat ttaagccatc tcctgatgac gcatagtcag
    15241 cccatcatga atgttgctgt cgatgacagg ttgttacaaa gggagaaggg catggcgagc
    15301 gtacagctgc aaaatgtaac gaaagcctgg ggcgaggtcg tggtatcgaa agatatcaat
    15361 ctcgatatcc atgaaggtga attcgtggtg tttgtcggac cgtctggctg cggtaaatcg
    15421 actttactgc gcatgattgc cgggcttgag acgatcacca gcggcgacct gttcatcggt
    15481 gagaaacgga tgaatgacac accgccagca gaacgcggcg ttggtatggt gtttcagtct
    15541 tacgcgctct atccccacct gtcagtagca gaaaacatgt catttggcct gaaactggct
    15601 ggcgcaaaaa aagaggtgat taaccaacgc gttaaccagg tggcggaagt gctgcaactg
    15661 gcgcatttgc tggatcgcaa accgaaagcg ctctctggcg gtcagcgtca gcgtgtggcg
    15721 attggccgta cgctggtggc cgagccaagc gtatttttgc tcgatgaacc gctctccaac
    15781 ctcgatgctg cactgcgtgt gcaaatgcgt atcgaaatct cccgtctgca taaacgcctg
    15841 ggccgcacaa tgatttacgt cacccacgat caggtcgaag cgatgacgct ggccgacaaa
    15901 atcgtggtgc tggacgccgg tcgcgtggcg caggttggga aaccgctgga gctgtaccac
    15961 tatccggcag accgttttgt cgccggattt atcggttcgc caaagatgaa cttcctgccg
    16021 gtaaaagtga ccgccaccgc aatcgatcaa gtgcaggtgg agctgccgat gccaaatcgt
    16081 cagcaagtct ggctgccagt tgaaagccgt gatgtccagg ttggagccaa tatgtcgctg
    16141 ggtattcgcc cggaacatct actgccgagt gatatcgctg acgtcatcct tgagggtgaa
    16201 gttcaggtcg tcgagcaact cggcaacgaa acccaaatcc atatccagat cccttccatt
    16261 cgtcaaaacc tggtgtaccg ccagaacgac gtggtgttgg tagaagaagg tgccacattc
    16321 gctatcggcc tgccgccaga gcgttgccat ctgttccgtg aggatggcac tgcatgtcgt
    16381 cgactgcata aggagccggg cgtttaagca ccccacaaaa cacacaaagc ctgtcacagg
    16441 tgatgtgaaa aaagaaaagc aatgactcag gagatagaat gatgattact ctgcgcaaac
    16501 ttcctctggc ggttgccgtc gcagcgggcg taatgtctgc tcaggcaatg gctgttgatt
    16561 tccacggcta tgcacgttcc ggtattggct ggacaggtag cggcggtgaa caacagtgtt
    16621 tccagactac cggtgctcaa agtaaatacc gtcttggcaa cgaatgtgaa acttatgctg
    16681 aattaaaatt gggtcaggaa gtgtggaaag agggcgataa gagcttctat ttcgacacta
    16741 atgtggccta ttccgtcgca caacaaaatg actgggaagc taccgatccg gccttccgtg
    16801 aagcaaacgt gcagggtaaa aatctgatcg aatggctgcc aggctccacc atctgggctg
    16861 gtaagcgctt ctaccaacgt catgacgttc atatgatcga cttctactac tgggatattt
    16921 ctggtcctgg tgccggtctg gaaaacatcg atgttggctt cggtaaactc tctctggcag
    16981 taacccgctc ctctgaagca ggtggttctt cctctttcgc cagcaacaat atttatgact
    17041 ataccaacga aaccgcgaac gacgttttcg atgtgcgttt agcgcagatg gaaatcaacc
    17101 cgggcggcac attagaactg ggtgtcgact acggtcgtgc caacctgcgt gataactatc
    17161 gtctggttga tggcgcatcg aaagacggct ggttattcac tgctgaacat actcagagtg
    17221 tcctgaaggg ctttaacaag tttgttgttc agtacgctac tgactcgatg acctcgcagg
    17281 gtaaaggtct gtcgcagggt tctggtgttg catatgttga cgaaaaattt tcctatgaca
    17341 ttaacaacaa cggtcacatg ctgcgtatcc tcgaccacgg tgcgatctcc atgggcgaca
    17401 actgggacat gatgtacgtg ggtatgtacc aggatatcaa ctgggataac gacaacggca
    17461 ccaagtggtg gaccgtcggt attcgcccga tgtataagtg gacgccgatc atgagtaccc
    17521 tgatggaaat cggctacgac aacgttaaat ctcaacgtac tggtgatacc aacaaccagt
    17581 acaaaatcac acttgctcaa caatggcagg ctggcgacag catctggtcg cgtccggcta
    17641 ttcgtgtttt tgccacctac gccaagtggg atgagaaatg gggttacgat tacaccgaca
    17701 aagctaaagg tactccgaac tacggcaaag ccgttccagc taacttcgaa ggcggcagct
    17761 tcggtcgtgg cgacagcgac gagtggacct tcggtgccca gatggaaatc tggtggtaat
    17821 agcaaaacct gggccggata aggtgcttgc gccgcatccg gcatccaacg cctgatgcga
    17881 cgcttgcgcg tcttatcagg cctacaacgg ctgtcaaatg taggccggat aaggcgttta
    17941 cgccgcatcc ggcataaaaa caggttgtca ttatctgaaa ggggcgcaag cccctctgat
    18001 tatcgggttt agcgcgctat tgcctggcta ccgctgagct ccagattttg aggtgaaaac
    18061 aatgaaaatg aataaaagtc tcatcgccct ctgtttatca gcagggttac tggcaagcgc
    18121 gcctggaatc agccttgccg atgttaacta cgtaccgcaa aacaccagcg acgcgccagc
    18181 cattccatct gccgcgctgc aacaactcac ctggacacca gtcgatcaat ctaaaaccca
    18241 gaccacccaa ctggcgaccg gcggccaaca actgaacgtt cccggcatca gtggtccggt
    18301 tgctgcgtac agcgtcccgg caaacattgg cgaactgacc ctgacgctga ccagcgaagt
    18361 gaacaaacaa accagcgtat ttgcgccgaa cgtgctgatt cttgatcaga acatgacccc
    18421 atcagccttc ttccccagca gttatttcac ctaccaggaa ccaggcgtga tgagtgcaga
    18481 tcggctggaa ggcgttatgc gcctgacacc ggcgttgggg cagcaaaaac tttatgttct
    18541 ggtctttacc acggaaaaag atctccagca gacgacccaa ctgctcgacc cggctaaagc
    18601 ctacgccaaa ggcgtgggta actcgatccc ggatattccc gatccggttg ctcgtcatac
    18661 cagcgatggc ttactgaaac tgaaagtcaa aacgaactcc agctccagcg tgttggtagg
    18721 accactattt ggttcttccg ctccagctcc ggttacggta ggcaacacgg cggcaccagc
    18781 tgtggctgca tccgctccgg caccggtgaa gaaaagcgag ccgatgctca acgacacgga
    18841 aagttatttt aataccgcga tcaaaaacgc tgtcgcgaaa ggtgatgttg ataaggcgtt
    18901 aaaactgctt gatgaagctg aacgcctggg atcgacatct gcccgttcca cctttatcag
    18961 cagtgtaaaa ggcaaggggt aattacgccc cacagtgctg attttgcaac aactggtgcg
    19021 tctcctggcg cacctttttt tatgcttcct tcttgggata tgagcgattt tttatagtaa
    19081 ctcacttctt cttcactaag aatgtccatt atctcaatgc cttatcagag attcttttcc
    19141 tttcgccggt agtgtctgga cattcaggct acttttccag gttattttat ttctgttatg
    19201 cagaggtttt atgataagtc atatcccaaa ttctggcggc aataactctt tga
//
LOCUS       DAZUDJ010000082        18493 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.082, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000082 DAZUDJ010000000
VERSION     DAZUDJ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18493
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.082"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..596)
                     /gene="rsmG"
                     /locus_tag="ACHY1N_004092"
     CDS             complement(<1..596)
                     /gene="rsmG"
                     /locus_tag="ACHY1N_004092"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFS4046300.1"
                     /translation="MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRV
                     RFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGR
                     FYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHL"
     gene            complement(660..2549)
                     /gene="mnmG"
                     /locus_tag="ACHY1N_004093"
     CDS             complement(660..2549)
                     /gene="mnmG"
                     /locus_tag="ACHY1N_004093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFS4046301.1"
                     /translation="MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRV
                     LYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     IGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREAS
                     GEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(2928..3371)
                     /gene="mioC"
                     /locus_tag="ACHY1N_004094"
     CDS             complement(2928..3371)
                     /gene="mioC"
                     /locus_tag="ACHY1N_004094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HFS4046302.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDL
                     SASGIWLIISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAI
                     DKLEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWINLLK"
     gene            complement(3461..3919)
                     /gene="asnC"
                     /locus_tag="ACHY1N_004095"
     CDS             complement(3461..3919)
                     /gene="asnC"
                     /locus_tag="ACHY1N_004095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HFS4046303.1"
                     /translation="MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTT
                     GHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            4071..5063
                     /gene="asnA"
                     /locus_tag="ACHY1N_004096"
     CDS             4071..5063
                     /gene="asnA"
                     /locus_tag="ACHY1N_004096"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HFS4046304.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EERLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPF
                     LPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDY
                     DDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLQL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL"
     gene            complement(5068..6519)
                     /gene="viaA"
                     /locus_tag="ACHY1N_004097"
     CDS             complement(5068..6519)
                     /gene="viaA"
                     /locus_tag="ACHY1N_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HFS4046305.1"
                     /translation="MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKA
                     AITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRL
                     NSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQ
                     ERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQ
                     LGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGG
                     TDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(6513..8009)
                     /gene="ravA"
                     /locus_tag="ACHY1N_004098"
     CDS             complement(6513..8009)
                     /gene="ravA"
                     /locus_tag="ACHY1N_004098"
                     /EC_number="3.6.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418202.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HFS4046306.1"
                     /translation="MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTS
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGAHVEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKE
                     IGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVD
                     LILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKT
                     ALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERSALEQWLS
                     KGGEIRGKLNGIGFAQKLNLEIDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQL
                     EELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVGAQIRQAQQC"
     gene            8232..10100
                     /gene="kup"
                     /locus_tag="ACHY1N_004099"
     CDS             8232..10100
                     /gene="kup"
                     /locus_tag="ACHY1N_004099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HFS4046307.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGV
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKH
                     GTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP
                     FFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHW
                     NKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            10267..10686
                     /gene="rbsD"
                     /locus_tag="ACHY1N_004100"
     CDS             10267..10686
                     /gene="rbsD"
                     /locus_tag="ACHY1N_004100"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709562.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFS4046308.1"
                     /translation="MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMAL
                     TQGVPSFMQVLGVVTNEMQVEAAIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIR
                     YTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF"
     gene            10694..12199
                     /gene="rbsA"
                     /locus_tag="ACHY1N_004101"
     CDS             10694..12199
                     /gene="rbsA"
                     /locus_tag="ACHY1N_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HFS4046309.1"
                     /translation="MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYARDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGLGVNDVSFTLR
                     KGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLASGIVYISE
                     DRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            12204..13169
                     /gene="rbsC"
                     /locus_tag="ACHY1N_004102"
     CDS             12204..13169
                     /gene="rbsC"
                     /locus_tag="ACHY1N_004102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HFS4046310.1"
                     /translation="MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTIN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
                     FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNK
                     IKIIVYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            13194..14084
                     /gene="rbsB"
                     /locus_tag="ACHY1N_004103"
     CDS             13194..14084
                     /gene="rbsB"
                     /locus_tag="ACHY1N_004103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HFS4046311.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAVFAQNDEM
                     ALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKV
                     LKGEKVQAKYPVDLKLVVKQ"
     gene            14210..15139
                     /gene="rbsK"
                     /locus_tag="ACHY1N_004104"
     CDS             14210..15139
                     /gene="rbsK"
                     /locus_tag="ACHY1N_004104"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFS4046312.1"
                     /translation="MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALTPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNK
                     TIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIR
                     TVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR"
     gene            15143..16135
                     /gene="rbsR"
                     /locus_tag="ACHY1N_004105"
     CDS             15143..16135
                     /gene="rbsR"
                     /locus_tag="ACHY1N_004105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HFS4046313.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELN
                     YAPSALARSLKLNQTHTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
                     SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTG
                     DFEFNGGFDAMRQLLSHPLRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDI
                     ELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQLTPILMERGSA"
     gene            complement(16101..17528)
                     /gene="mdtD"
                     /locus_tag="ACHY1N_004106"
     CDS             complement(16101..17528)
                     /gene="mdtD"
                     /locus_tag="ACHY1N_004106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtD"
                     /protein_id="HFS4046314.1"
                     /translation="MSDKKKRSMAGLPWIAAMAFFMQALDATILNTALPAIAHSLNRS
                     PLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFTLAVSLFTLGSLACALSNSLPQL
                     VVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVAMPGLVGPILGPVLGGVLVT
                     WATWHWIFLINIPIGIAGLLYARKHMPNFTTARRRFDITGFLLFGLSLVLFSSGIELF
                     GERIVASWIALTVIVTSIGLLLLYILHARHTPNPLISLDLFKTRTFSIGIVGNIATRL
                     GTGCVPFLMPLMLQVGFGYQAFIAGCMMAPTALGSIIAKSMVTQVLRRLGYRHTLVGI
                     TVIIGLMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITLADLTDDNASSGN
                     SVLAVTQQLSISLGVAVSAAVLRVYEGMEGTTTVEQFHYTFITMGIITVASAAMFMLL
                     KTTDGNNLIKRQRKSKPNRVPSESE"
     gene            complement(17551..18243)
                     /gene="yieP"
                     /locus_tag="ACHY1N_004107"
     CDS             complement(17551..18243)
                     /gene="yieP"
                     /locus_tag="ACHY1N_004107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFS4046315.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGEYEPGTILPGEIELG
                     EQFGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQSNWNFLDQELLTWWMTEENFHQ
                     VIDHFLVMRICLEPQACLLAATVGTAEQKAHLNTLMAEMSALKENFRRERWIEVDMAW
                     HEHIYEMSANPFLTSFASLFHSVYHTYFTSITSDTVIKLDLHQAIVDAIVQSDGDAAF
                     KACQALLRSPDK"
BASE COUNT         4458 a         4591 c         4832 g         4612 t
ORIGIN      
        1 agatggcgtt cgccatccag ggcaggaacc tgaagtttaa ccactgattc aacctgatat
       61 tcttcgggca acaaagcgat ttcatcttcc ggcatttgcc ctttcagcgc gtagaaacgg
      121 ccttgctcac caggaagatg gtgacaccag ctcaccatat cgttcagaga ggcaaaagcg
      181 cggctaatta cgccatcaaa tggcggctct gaaggaaact cttctaccct gctctgtact
      241 ggctcaatat tctccagttt aagctcatgt tgcacctgac gaaggaaacg cacgcgttta
      301 ccaaggctat ccaacagagt gaaatgggct tcaggacgca cgatagagag tggaatgcca
      361 ggcagtccag gaccggtgcc gacatcgata aaccgttcac cttgcagata cggtgccacc
      421 acaatgctat cgagaatatg gcgtaccagc atctcattag gatcgcggac cgaagtcagg
      481 ttgtacgctt tgttccattt atgcagcata ttcacgtagg caataagctg gtttttctgg
      541 tgatcggtaa gcgaaatacc tgcgtctttc agcagtaagg agagtttgtt gagcacggtg
      601 attacctgtt cttgatgcgt tgcctggtaa gcgggtgctt accaggcatt tttaatgcgt
      661 tatgcgctac gacgcagcat accctgtttt ttcagccaca ccagcagaat ggagatggcc
      721 gcaggcgtga cgccagaaat acgtgaagcc tggccgatag aggccggttt gtgatcgtta
      781 agtttggcga tcacttcgtt agaaagaccg gatacctggc ggtaatccag tgtcgctggt
      841 agcagggtgt tctcgttacg cagctgcttt tcgatctcat cttgctggcg cgcgatataa
      901 ccttcgtatt taacctgaat ctcaacctgt tccgccgcct gttcgtctgt caacgcaggg
      961 gcaaacggcg tcagcgtggt taatttttca taagtcattt ccggacgacg cagcagatct
     1021 tcaccactgg cttcacggga aagcggcgca gtcaggtgag cattcacttc ggctgcagct
     1081 tccgccgacg gggttaccca ggtcgatttc agacgctgac gctcacgctc gatattctca
     1141 agtttctcgt taaagcgcgc ccaacgttcg tcatccacca ggcccagttc acgaccgatt
     1201 tcagtcaaac gcagatccgc attatcttcg cgcagcatca gacgatattc tgcgcgcgaa
     1261 gtaaacatac gatacggttc tttggttcct aaagtgcaca ggtcatcaac cagtacgccg
     1321 agataggcct gagaacgcgc cggagcccaa ccttctttgt cagcagacag acgggcagcg
     1381 ttaagaccgg ccagcaaacc ttgcgcagcg gcttcttcgt aaccggtagt gccgttaatc
     1441 tgaccagcaa agaacagccc ctggataaac ttgctctcca gcgtcggttt caggtcgcga
     1501 ggatcgaaga agtcatactc aatggcataa cccggacgca cgatcttcgc gttttccatc
     1561 ccctgcatag agcggacgat ttgcatctgc acatcgaacg gcaggctggt ggagataccg
     1621 ttcggataaa tttcgttaga agtcagccct tccggttcaa ggaagatctg atgctgattt
     1681 ctgtcggcga agcgcatgac tttgtcttcg atcgacgggc agtagcgtgg gccgacacct
     1741 tcgatcaccc ctgcatacat tgggctacga tcgaggttac tgcggatcac atcatgggtt
     1801 ttctcgttgg tatgagtgat ataacacggc acctgctggg gatgctggga cgcattgccc
     1861 ataaacgaga ataccggcat tgggttatcg ccatgctgtt gcgccagcac actaaagtcg
     1921 atagttcgag catcaatacg cggtggtgtc ccggttttca gacgaccaac gcgcagcggc
     1981 agttcacgca aacggcgaga aagcggaatg gacggcggat caccagcacg gccaccgctg
     2041 taattatcca gaccgatatg aattttaccg tcgaggaacg tcccaacggt gagcacgacg
     2101 gctttggcac ggaacttcag tcccatttgg gtaacagcac cgaccacgcg atcgttttcg
     2161 acaataagat cttcaaccgc ctgctggaag atcatcaggt tcggttggtt ctccagcgcc
     2221 gtacgtaccg cctgacggta gagcacacga tccgcctgag ctcgggtagc gcgaaccgcc
     2281 ggtcctttgc ttgcgtttag tatcctaaac tggatacccg cttgatcgat cgctttcgcc
     2341 atcagaccgc cgagtgcatc cacttctttt accagatgtc ccttcccaat accgccgatc
     2401 gccgggttgc agctcatctg ccccagagtg tcgatattgt gtgtcaaaag cagagtctgt
     2461 tgacccatac gcgccgcggc catcgcggcc tcggtgcctg catgaccccc gccaatgatg
     2521 atgacgtcaa aaggatccgg ataaaacatg gtgattgcct cgcataacgc ggtatgaaaa
     2581 tggattgaag cccgggccgt ggattctact caactttgtc ggcttgagaa agacctggga
     2641 tcctgggtat taaaaagaag atctatttat ttagagatct gttctattgt gatctcttat
     2701 taggatcgca ctgccctgtg gataacaagg atccggcttt taagatcaac aacctggaaa
     2761 ggatcattaa ctgtgaatga tcggtgatcc tggaccgtat aagctgggat cagaatgagg
     2821 ggttatacac aactcaaaaa ctgaacaacc gttgttcctt ggataactac cggttgatcc
     2881 aagcttcctg acagagttat ccacagtaga tcgcacgatc tgtatactta tttgagtaaa
     2941 ttaatccacg atcccagcca ttcttctgcc ggatcttccg gaatgtcgtg atcaagaatg
     3001 ttgatcttca gtgtttcgcc tgtctgtttt gcaccggaat ttttgagttc tgcctcgagt
     3061 ttatcgatag ccccacaaaa ggtgtcatat tcacgactac caataccgat tgcgccaaag
     3121 cggaccgcag aaagatcggg cttctgttcc tgcaatgctt catagaaagg agaaaggttg
     3181 tccggaatat ctccggcacc gtgggtggag ctgataatca gccagatccc cgaggcagat
     3241 aaatcttcca acagcggacc gtgcagcgtt tcggtggtaa aacccgcctc ttccagcttt
     3301 tcagccaggt gttctgctac atattcggca ccgccgaggg tgctgccgct gataagagtg
     3361 atatctgcca taaaccgcca cctttattaa gagtggcgta ttgtacgctg tgaacgcgtt
     3421 gggatctacc tgtggaaaag tatgggatta aaaaagccga tcagggcttg atagtacgca
     3481 tgatcgggtt ttgcaggacg atcaatgtct cggtggactg aatttcatca attgtttgga
     3541 tcttgttgat aagtacatgc tggagagcgt cgatcgaacg gcacattact tttataaaga
     3601 tgctgtagtg gccggttgtg taataggctt cagtgacttc atcaaggctt tccagctttg
     3661 ccagcgcgga agggtagtct ttggcgctct ttaatataat gccgataaag cagcctacgt
     3721 cataaccgag ctgcttcggg ctgacatcaa tacgcgcccc ggtaatgatc cccgcctgct
     3781 tcattttctc tactcgaacg tgaatcgtcc ccggactgac gccaaattgt ttcgccagtt
     3841 cggcgtaagc ggtgcgcgca ttgcccatta atgcttccag gatgccacgg tccagattgt
     3901 cgatcagata attttccata ggattttctt atgcagattg atgattcatt ctattttagc
     3961 cttctttttt aatgaatcaa aagtgtgtta ggctttttat tgaatgatta ttgcatgtgt
     4021 gtcggttttt gttgcttaat cataagcaac aggacgcagg agtataaaaa atgaaaaccg
     4081 cttacattgc caaacaacgc caaattagct tcgtgaaatc tcacttttct cgccaactgg
     4141 aagaacgtct ggggctgatc gaagtccagg cgccgattct tagccgtgtg ggggatggca
     4201 cgcaggataa cttgtcgggc tgtgaaaaag cggtgcaggt aaaagtgaaa gctctgcctg
     4261 atgcccagtt cgaagtggtt cattcactgg cgaagtggaa acgtcagacc ttagggcaac
     4321 acgacttcag cgcgggcgaa gggctgtaca cgcacatgaa agcccttcgc cccgatgaag
     4381 agcgtctttc tccgttgcac tcggtctatg ttgaccagtg ggactgggaa cgcgtaatgg
     4441 gcgacggtga gcgtcaattc tcgactctga aaagcacggt agaggcgatc tgggcgggaa
     4501 ttaaagcaac cgaagctgca gttagcgaag agtttggttt ggcaccgttc ctgccggatc
     4561 agatccactt cgtacacagc caggagttac tgtctcgtta tccggatctc gatgccaaag
     4621 ggcgtgagcg ggcgattgcg aaagatcttg gcgcggtatt cctcgtcggg attggcggca
     4681 agctgagtga tggtcatcgt cacgacgtgc gcgcaccgga ttatgatgac tggagcaccc
     4741 cgtcagagct gggccatgcg ggtctgaacg gcgatattct ggtatggaac cctgtactgg
     4801 aagatgcgtt tgagctttct tccatgggga tccgcgtgga tgccgacacg ttgaagcatc
     4861 agttggcgct gaccggtgat gaagatcgtc tgcagctgga atggcatcag gcgctgctgc
     4921 gcggtgaaat gccgcagacc atcggcggcg gtatcggcca gtctcgtttg accatgctgc
     4981 tgctgcaact gccgcatatc ggccaggttc agtgtggagt atggccagct gctgttcgcg
     5041 agagcgtccc ttctctgctg taataattta tcgccgccag cgtctgagca ggcggcttcg
     5101 catcccggta tcaaagcgcc agatatgatc gaaaatgcgc atgatgccgg gtttgccgtg
     5161 tgccgacatc gccacggcat gaaagcgatg ctgatgtacc cgctgcagct ctttcacttt
     5221 actcgtcacg tcgtcaggca accgctgagc gataaaatca gaaatcacca ccgcatcggc
     5281 atcaaaccat tccctgcttt gcaagcgttc cataatggcg cgaaaacaac tggcaagatc
     5341 ggtgccgcca cgaaactgct ggcttaaaaa acggattgct tgttcgatgc cttgtgggcc
     5401 tgaaagctca taacggacga tctcggtgga aaatagcata atatagcagc gccggttttc
     5461 tgcgagagca atgcgcatca aggccaggca gaacgctttc gcacactgtt cattaaagcc
     5521 gcccattgag ccggaagtat ccacacagac aataaacggc ccgcgcggct gttcatcgta
     5581 atctttatgt accaccggac gttcgatcac tttttcacgc cacgactcac cgtgcaggcg
     5641 ataggtgagc aactgttttt ccaccagccg acggtaaaac tcatactcca gttccgttat
     5701 ccctagtgtc gccagttctg gcggcagaag acgtaaaata tcatcgcttt gttgcagacc
     5761 atcaacctgc tcaggaaccg tcgccggttc gcgcaccatg gtgcggaagg tttccatctg
     5821 cgcatcgttg cgcggtattg atttggcttc ccgagaacgc cccagctgct ctgccaggcg
     5881 tttcagttcc ggctgttcgt taagaaattc accgtatttc acaatcaact gatagtcgcc
     5941 acgtttaagc tgaccggcgc tcatatccca cagacgacca gctgcagtat tgttatctgc
     6001 gagaatcggt tcaagttgtc cgctcagcgt catgcgttcc tgaacttcac tcaacagttg
     6061 ttcgcgttct tcttctaata gctgttgatt taacgtcgtt gcttgcacga tcagacttaa
     6121 acgccaacgc tggagaaaaa gcgtgtgtaa cgctgaagtg atcgtgctgt tagcatcaac
     6181 caactgtcgg gcttgttctg cccatggaga attcagacga tgcagtaagt ccaggatctg
     6241 tggtagctgc acaataaact gtggcgtgga gaggagctgg ctttgctgat agcacatcac
     6301 ctcttcggtg agttccggcg ggactcgggc atctttcagc cgactgcgca gcgcttcacg
     6361 ccagcgggga acatcatcag tgattgccgc cttcaggcgt gggaattttt caaagaagac
     6421 cgccagctgc ggtgaggcca gcagtgcgat gatcatctct tcgatcaatc cctcttcgct
     6481 gacggccagc atcacattaa gcgtatccag cgttagcatt gttgtgcctg gcgaatctgt
     6541 gcaccgacat cctgtaggct ggcttcaatg cgacctaacc agtcgccagg gataaacaga
     6601 catttttgct gttcgctgaa taaagcgtgt tgcttgcgcc agtcgctttc aagctcttcc
     6661 agttgttgtt ttatttcacc aggcagacct tcagccgatg aaccgggaag tgccagcgta
     6721 ctgccttgta aacttacatc gcgaacgaca agatgttggg cgctatcaat ttccagattc
     6781 agtttctggg caaagccgat accgttcagt ttaccgcgaa tttcaccacc tttgctcagc
     6841 cactgttcca gcgcgctacg ctcaaaggag atatgaacca cttccatatc atgcagtttt
     6901 aacggttttt gcagcagtag agtcagagtg gaagcagtaa cgttaacagg aagttgatac
     6961 tgctgacgac ggctgaaaat gccgcccaga cgaattaccg ttaaggctgt tttatcgctt
     7021 tgttgctgct ggagttgcag gtgacgttgc acaatcgcgc caaggcgagt caacatccct
     7081 tgctgttgcc aggcgtgacc ggtcatcaat acatcaattt gttgttgtat caaattcagg
     7141 ctttgcgcgt cataccacag gcaatctttc agcaaaatga gatctaccgg ggcaacagca
     7201 ctgcgaccgc taaaaaaggc gctggcctgc aataatcgga tcgctttttt ccagcgacga
     7261 tccgagacat aaggcgcatc cggtaattta tccagttgct ggcgcagcat aaaaatcagc
     7321 tcaaatacat gatcgggcag cgtaatttca ccaatctctt tctgccagcg ttcatattct
     7381 tcatctgtga cctgcaaggc atcaggaacc ggattgtcgt tttcatcctg ttgactggtc
     7441 agcatggagc ggaaattcgc tttatcctgc actttatcta accacagacg aatcagcatg
     7501 cggtcatata acgcttccag actgctgtct gcttccggca gctcgttgga ggccgccacc
     7561 agcagacgca tcgggatttt ttctacgtgt gcaccgttgc ggaactggcg ctcgttaatg
     7621 gcggtgagca aggtattaag aattgccggg cccgctttcc agatctcatc cagaaagaca
     7681 atttctgctt ccggcaggta accgctggtt aaacgttcat agcgcccttc atcttttagc
     7741 gcctgaatag aaaggggacc aaaaacttct tccggcgtgg agaagcgggt catcagatat
     7801 tcaaacgcgc gggcattctg aaaggcgaat tttaagcgcc gggcgatcaa acttttggca
     7861 atacctggcg ggccaaggag gaacacactt tcaccactta atgccgctaa taaacacaag
     7921 cggatggcgt ggctacgttc ataaagcccc ttttccaacg aactgctcag gcgggaaatt
     7981 ctttccgcta ataaatgagg gtgagccata atgaagtggc gtcctttcgt caaaagttct
     8041 gcgtaaattg cgagtataga cgtttcttgc tggtggctaa aatagtctca aagggggggt
     8101 atttttcttt gagccaggtt aatgtggccg catttaggag tacgattttg ccgttaatcg
     8161 tgcatactgt gcgctttttt gtgggccaag ggactaagca cacatttcat atttcaacga
     8221 aagactagtc tatgagcact gataataagc aatcattgcc cgcgattacc ctcgcggcga
     8281 ttggagttgt ctacggcgat attggtacca gcccgttata tacacttcgt gaatgtttgt
     8341 ccggccagtt tggttttggc gttgaacgcg atgccgtgtt tggcttttta tcgctgatct
     8401 tctggctgct aatctttgtg gtttccatta aatatctcac cttcgtgatg cgggcagata
     8461 acgccggtga gggggggatc ctgacgttga tgtcgcttgc cgggcgtaat acgtcggcgc
     8521 gaaccacatc aatgctggtg attatggggc taatcggcgg cagctttttc tatggtgaag
     8581 tcgtcataac acccgctatt tcggtgatgt cagccattga aggtctggaa atcgtcgccc
     8641 cgcagctgga tacctggata gttcccctct caattatcgt tctcacttta ttatttatga
     8701 ttcaaaaaca tggcacggct atggtcggta agctgtttgc gccgatcatg ctgacctggt
     8761 ttttgattct ggcaggactg gggttacgta gcattattgc taacccggaa gtgctgcatg
     8821 cgctgaatcc aatgtgggcg gtgcatttct tccttgaata caaaacggtt tcttttattg
     8881 cattaggggc agtggtgttg tcgattacgg gggtcgaggc gctgtatgct gatatggggc
     8941 actttggtaa gttccctatt cgcctggcgt ggttcaccgt cgtattacct tccttgaccc
     9001 ttaattactt cggtcaggga gcgctgttgt taaagaaccc ggaagcgatt aagaacccgt
     9061 tcttcctgtt ggcaccggac tgggcgctga tcccgctgct gatcatcgcc gcactggcga
     9121 cggtaattgc ctcgcaggcg gttatctctg gcgtcttctc attgacgcgt caggcggtac
     9181 gtctgggata tttgtcgccg atgcgcatta ttcacacctc cgaaatggag tcagggcaaa
     9241 tctatattcc gtttgtgaac tggatgctct atgtcgcggt cgtgattgtg attgtcagct
     9301 ttgagcactc cagcaacctg gcggcggcgt acgggattgc ggtgaccgga accatggtgc
     9361 tgacgtctat tctctcgact accgtggcac gtcagaactg gcactggaat aagtattttg
     9421 ttgcgctgat cctgattgct ttcctttgtg tcgatattcc attgttcacc gctaacctcg
     9481 ataaactgct ctccggcggc tggttgccat tgagcctcgg tactgtgatg tttatcgtga
     9541 tgaccacctg gaagagcgag cgtttccgct tgctgcggcg gatgcatgaa catggtaact
     9601 ctctggaagc gatgattgct tcgctggaga aatcaccgcc tgttcgcgtg cccgggaccg
     9661 cggtgtatat gtcgcgtgca atcaacgtca ttccctttgc gctgatgcat aaccttaaac
     9721 ataacaaggt attgcatgag cgggtgattc tgttaactct gcgtaccgaa gacgcgccat
     9781 atgtccataa tgtccgtcgg gtacagattg aacaactgtc gcccactttc tggcgcgtgg
     9841 tggcaagtta tggttggcga gaaacgccaa acgtggaaga agttttccac cgctgcggtc
     9901 tggaaggatt aagttgccgg atgatggaaa cctccttctt tatgtcgcat gagtcgttga
     9961 tcctcggcaa acgcccgtgg tatttgcgtc tgcgcggcaa gctgtacttg ctgctgcaac
    10021 gtaatgcgct gcgtgcacca gatcaatttg aaattccgcc aaacagggtt atcgaactgg
    10081 gtactcaggt cgaaatctaa cgccagacgc ctcctttctc cataaggggg cgtttttgtt
    10141 ttcatggtta atcaccatgt aaaacgtttc gaggttgatc acatttccgt aacgtcacga
    10201 tggttttccc aactcagtca ggattaaact gcgggtcagc gaaacgtttc gctgatggag
    10261 aaaaaaatga aaaaaggcac cgttcttaat tctgatattt catcggtgat ctcccgtctg
    10321 ggacataccg atacgctggt ggtgtgtgat gctggtttac ccatccccaa aagtacaacg
    10381 cgtatcgata tggcattaac ccagggtgta ccttctttta tgcaggtgct gggcgtcgtc
    10441 acaaatgaaa tgcaggtcga ggctgccatt atcgcggaag agatcaaaca acataatccg
    10501 caactccacg aaacgttgct cactcacctt gagcagctgc aaaaacacca gggaaatacc
    10561 attgaaattc gttacaccac gcatgaacaa ttcaaacaac aaaccgcaga aagtcaggcg
    10621 gtaattcgca gcggagaatg ttctccgtat gcgaatatca ttctctgtgc tggcgtgacg
    10681 ttctgaggcc gtcatggaag cattacttca gcttaaaggc atcgataaag ccttcccggg
    10741 cgtaaaagcc ctctcgggcg cagcgttaaa tgtctatccg ggccgcgtga tggcgctggt
    10801 gggcgaaaac ggcgcgggta aatccaccat gatgaaagtg cttactggta tctatgctcg
    10861 cgatgccggc acgcttttat ggctggggaa agaaacgaca tttaccgggc cgaaatcttc
    10921 ccaggaagcc gggattggga ttatccatca ggaactgaac ctgatcccgc agttgaccat
    10981 tgccgaaaac attttcctcg gtcgtgagtt tgttaatcgc tttggcaaaa ttgactggaa
    11041 aaccatgtat gccgaagcgg ataaattgct ggctaaactt aacctgcgct ttaaaagcga
    11101 caagctggtg ggcgatcttt ccatcggtga ccagcaaatg gttgaaatcg ccaaagtgct
    11161 gagctttgag tcgaaagtca tcattatgga tgaaccgacc gatgcgctga ccgataccga
    11221 aaccgaatcc ctgttccgcg tcatacgcga gctgaaatcg caaggccgcg gtattgtcta
    11281 tatctcccac cgcatgaaag aaatcttcga gatttgcgat gacgttaccg tttttcgtga
    11341 cgggcaattt attgctgagc gcgaagtggc atcactgacc gaagattcgc tgattgagat
    11401 gatggtgggc cgcaagctgg aagatcaata tccacacctg gacaaagcgc cgggagatat
    11461 ccgcctgaaa gtcgataatc tctgcggact tggcgttaac gatgtctctt ttactttacg
    11521 caaaggcgaa attcttggcg tctctggttt gatgggcgca ggtcgtaccg aactgatgaa
    11581 agtgctctac ggcgcactac cgcgcaccag cggttacgtc accctggatg ggcatgaagt
    11641 cgttacccgt tcaccgcagg atggcctggc aagcggcatt gtgtatatct ccgaagaccg
    11701 taaacgtgac ggtttagtgt tgggcatgtc agtaaaagag aacatgtcgc tgacagcgct
    11761 gcgctacttc agccgcgctg gcggcagttt gaagcatgcc gatgaacagc aggctgtgag
    11821 tgatttcatt cgtctgttta atgtgaaaac accgtcgatg gaacaggcaa ttggtctgct
    11881 ttccggtggc aatcagcaaa aagtggcgat tgcccgcggt ctgatgacac gccccaaagt
    11941 gttgatcctt gatgaaccta cccgtggcgt agatgtcggc gcgaaaaaag agatctatca
    12001 actgattaac cagttcaaag ccgatggctt gagcatcatt ctggtgtcat cggagatgcc
    12061 agaagtatta ggcatgagcg atcgcatcat cgtcatgcat gaagggcatc tcagcgggga
    12121 atttactcgt gagcaggcca cccaggaagt gttaatggct gccgctgtgg gcaagcttaa
    12181 tcgcgtgaat caggagtaaa aaaatgacaa cccagactgt ctctggtcgc cgttatttca
    12241 cgaaagcgtg gctgatggag cagaaatcgc ttatcgctct gctggtgctg atcgcgattg
    12301 tctcgacgtt aagcccgaac tttttcacca tcaataactt attcaatatt ctccagcaaa
    12361 cctcggtgaa cgccattatg gcggtcggga tgacgctggt gatcctgacg tcgggcatcg
    12421 acttgtctgt aggttctctg ttggcgctaa ccggcgcagt tgctgcatct atcgtcggca
    12481 ttgaagtcaa tgcgctggtg gctgtcgctg ctgctctcgc gttaggtgcc gcaattggtg
    12541 cggtaaccgg ggtgattgta gcgaaaggtc gcgttcaggc gtttatcgct acgctggtta
    12601 tgatgctttt actgcgcggc gtgaccatgg tttataccaa cggtagccca gtgaataccg
    12661 gctttactga gaacgccgat ctgtttggct ggtttggtat tggtcgtccg ctgggcgtac
    12721 cgacgccagt ctggatcatg gggattgtct tcctcgcggc ctggtacatg ctgcatcaca
    12781 cgcgtctggg gcgttacatc tacgcgctgg gcggcaacga agcagcaacg cgtctttctg
    12841 gtatcaacgt caataaaatc aaaatcatcg tctattctct ttgtggtctg ctggcatcgc
    12901 tggccgggat cattgaagtg gcgcgtctct cctccgcaca acccacggcg gggactggct
    12961 atgagctgga tgctattgct gcggtggttc tgggcggtac gagtctggcg ggcggaaaag
    13021 gtcgcattgt tgggacgttg atcggcgcat taattcttgg cttccttaat aatggattga
    13081 atttgttagg tgtttcctcc tattaccaga tgatcgtcaa agcggtggtg attttgctgg
    13141 cggtgctggt agacaacaaa aagcagtaat aacgactaca ggacatcttg aatatgaaca
    13201 tgaaaaaact ggctaccctg gtttccgctg ttgcgctaag cgccaccgtc agtgcgaatg
    13261 cgatggcaaa agacaccatc gcgctggtgg tctccacgct taacaacccg ttctttgtat
    13321 cgctgaaaga tggcgcgcag aaagaggcgg ataagcttgg ctataacctg gtggtgctgg
    13381 actcccagaa caacccggcg aaagagctgg cgaacgtgca ggacttaacc gttcgcggca
    13441 ccaaaattct gctgattaac ccgaccgact ccgacgcagt aggtaatgct gtgaagatgg
    13501 ctaaccaggc gaacatcccg gttatcactc ttgaccgcca ggcaacgaaa ggtgaagtgg
    13561 tgagccacat tgcttctgat aacgtactgg gtggcaaaat cgccggtgat tacatcgcga
    13621 agaaagcggg tgaaggtgcc aaagttatcg agctgcaagg cattgctggt acatccgcag
    13681 cccgtgaacg tggcgaaggc ttccagcagg ccgttgctgc tcacaagttt aatgttcttg
    13741 ccagccagcc agcagatttt gatcgcacta aaggtttgaa cgtaatgcag aacctgttga
    13801 ccgctcatcc ggatgttcag gctgtattcg cgcagaatga tgaaatggcg ctgggcgcgc
    13861 tgcgcgcact gcaaactgcc ggtaaatcgg atgtgatggt cgtcggattt gacggtacac
    13921 cggatggcga aaaagcggtg aatgatggca aactagcagc gactatcgct cagctacccg
    13981 atcagattgg cgcgaaaggc gtcgaaaccg cagataaagt gctgaaaggc gagaaagttc
    14041 aggctaagta tccggttgat ctgaaactgg ttgttaagca gtagttttaa tcaggttgta
    14101 tgacctgatg gtgacataaa tacgtcatcg acagatgaac gtgtaatata aagaaaagca
    14161 gggcacgcgc caccctaaca cggtggcgca ttttatggac atcccgaata tgcaaaacgc
    14221 aggcagcctc gttgttcttg gcagcattaa tgctgaccac attcttaatc ttcaatcttt
    14281 tcctactcca ggcgaaaccg taaccggtaa ccactatcag gttgcatttg gcggcaaagg
    14341 cgcgaatcag gctgtggctg ctgggcgtag cggtgcgaat atcgcgttta ttgcctgtac
    14401 gggtgatgac agcattggtg agagcgttcg ccagcagctc gccactgata acattgatat
    14461 tactccggtc agcgtgatca aaggcgaatc aacaggtgtg gcgctgattt ttgttaatgg
    14521 cgaaggtgag aatgtcatcg gtattcatgc cggcgctaat gctgccctta ccccggcgct
    14581 ggtggaagcg caacgtgagc gtattgccaa cgcgtcagca ttattaatgc agctggaatc
    14641 accactcgaa agtgtgatgg cagcggcgaa aatcgcccat caaaataaga ctatcgttgc
    14701 gcttaacccg gctccggctc gcgaacttcc tgacgaactg ctggcgctgg tggacattat
    14761 tacgccaaac gaaacggaag cagaaaagct caccggtatt cgtgttgaaa atgatgaaga
    14821 tgcagcgaag gcggcgcagg tactgcatga aaaaggtatc cgtactgtac tgattacttt
    14881 aggaagtcgt ggtgtatggg ctagcgtgaa tggtgaaggt cagcgcgttc ctggattccg
    14941 ggtgcaggct gtcgatacca ttgctgccgg agataccttt aacggcgcgt taatcacggc
    15001 gttgctggaa gaaaaaccat tgccagaggc gattcggttt gcccatgctg ccgctgcgat
    15061 tgccgtaaca cgtaaaggcg cacaaccttc cgtaccgtgg cgtgaagaga tcgacgcatt
    15121 tttagacagg cagaggtgac gcttggctac aatgaaagat gttgcccgcc tggcgggcgt
    15181 ttctacctca acagtttctc acgttatcaa taaagatcgc ttcgtcagtg aagcgattac
    15241 cgccaaagtt gaagcggcga ttaaagaact caattacgcg ccatcagccc tggcgcgtag
    15301 cctcaaactc aatcaaacac ataccattgg catgttgatc actgccagta ccaatccttt
    15361 ctattcagaa ctggtgcgtg gcgttgaacg cagctgcttc gaacgcggtt atagtctcgt
    15421 cctttgcaat accgaaggcg atgaacagcg gatgaatcgc aatctggaaa cgctgatgca
    15481 aaaacgcgtt gatggcttgc tgttactgtg caccgaaacg catcaacctt cgcgtgaaat
    15541 catgcaacgt tatccgacag tgcctactgt gatgatggac tgggctccgt tcgatggcga
    15601 cagcgatctt attcaggata actcgttgct gggcggagac ttagcaacgc aatatctgat
    15661 cgataaaggt catacccgta tcgcctgtat taccggtccg ctggataaaa ctccggcgcg
    15721 cctgcggttg gaaggttatc gggcggcgat gaaacgtgcg ggtctcaaca ttcctgatgg
    15781 ctatgaagtc actggtgatt ttgaatttaa cggcgggttt gacgccatgc gccaactgtt
    15841 atcacatccg ctgcgtcctc aggccgtctt taccggaaat gacgctatgg ctgttggcgt
    15901 ttaccaggcg ttatatcagg cagagttaca ggttccgcag gatatcgcgg tgattggcta
    15961 tgacgatatc gaactggcaa gctttatgac gccaccatta accactatcc accaaccgaa
    16021 agatgaactg ggggagctgg cgattgatgt actcatccat cggataaccc agccgaccct
    16081 tcagcaacaa cgattacaac ttactccgat tctgatggaa cgcggttcgg cttagattta
    16141 cgctgtcttt tgatcaaatt attaccatcg gttgttttca gaagcatgaa cattgctgct
    16201 gaagcaacag taataatgcc catcgtgata aacgtatagt ggaattgttc gacagtcgtt
    16261 gtgccttcca tcccttcata aacgcgaagg acggccgcac ttacagcaac gcctaaacta
    16321 atcgacagtt gctgcgtgac cgccagaaca ctgttaccgc tgctggcgtt gtcatcggtc
    16381 agatcggcaa gtgtgatggt attcatcgcg gtaaattgcg tcgacatagc catccctaat
    16441 ataaacaacg gcaagatcag catccatatc gccattgccg gtgattgcaa agagaactga
    16501 gcgatcatta gcccaataat caccgtgatc cccactaacg tatggcgata gcccagacga
    16561 cgtaagactt gggtaaccat cgattttgca ataatggaac ctaacgctgt cggtgccatc
    16621 atacagccgg caataaacgc ctgataacca aatcctacct gtaacatcaa tggcataagg
    16681 aacggtacac aaccggtccc cagacgggtt gcaatattgc ctacgatacc gatcgagaaa
    16741 gtgcgggttt taaataaatc taatgaaatt aatgggtttg gcgtgtgtcg cgcatggaga
    16801 atatagagaa gcagtaaccc gatgctggtg acaattaccg tcaaggcaat ccagctggcg
    16861 acaatccttt ccccgaatag ctctattccg cttgagaaga gaacaaggct gaggccaaac
    16921 agcaaaaagc cagtgatatc gaatctgcgt cgtgcggtgg tgaaattggg catatgtttg
    16981 cgcgcgtaaa gaaggcccgc aatacctatg gggatattga ttaaaaatat ccagtgccag
    17041 gttgcccagg tgaccagcac gccgccaaga acggggccta aaattggccc caccagaccc
    17101 ggcatggcga caaaattcaa tactggaaga agttcattac gaggataagc gcgcagtaag
    17161 gccagccgag caacaggcat catcattgcg ccgcctatcc cctgaataac ccggaagaca
    17221 accagctgtg gtagcgaatt agaaagtgcg caggccagag aacccaatgt gaacagactc
    17281 acggcaaggg taaaaatgcg acgcgtaccg aagcgatcgg ctagccatcc gcttaccgga
    17341 ataagcatcg ccaccgtcag cgtataactg atgatggctg attgcatcgc gagaggagaa
    17401 cgattaaggc tatgagcgat tgcgggtaag gcggtattca gaatagtggc atcaagtgcc
    17461 tgcatgaaga aggccatcgc cgcgatccac ggcaaacccg ccatactgcg cttcttttta
    17521 tcgctcattc aatgtcctgt tatcgggttg tcacttatca ggtgagcgta gcagcgcctg
    17581 acaagcttta aatgccgcgt cgccatcgct ttggacaatc gcatcgacaa tcgcctggtg
    17641 cagatccagc tttatcactg tgtcgctggt aattgacgtg aagtaagtgt gataaaccga
    17701 atggaatagc gaggcgaatg aggtcaaaaa cggattggcg ctcatttcat agatatgctc
    17761 atgccaggcc atatcgactt cgatccagcg ttcacggcga aagttctctt ttaatgccga
    17821 catttcggcc attaacgtat tgagatgcgc cttctgttcc gcggtgccaa ccgttgcagc
    17881 cagtaggcaa gcttgcggct ccagacagat acgcataacc agaaagtgat cgatgacctg
    17941 atgaaagttc tcttctgtca tccaccaggt aagcaattcc tgatcaagaa aattccagtt
    18001 tgattgtggc atgacccggg taccaattcg cggtcgcggt aaaaccatcc cttttgccgt
    18061 taacgttttg accgcttcgc gtaccgctgt acgactcact ccaaattgct cgcccagctc
    18121 aatctcacca ggcaaaatgg tgccgggttc atattcacct tttaagatgc gttgcgccag
    18181 cttctcagcc agaacatacg aaaggttttt ctgtgcagct aactgttgtg cgcttaaagg
    18241 cattactaat cttccttttt ctttttattc ctccttagta tgccaccagg aagtgtgatt
    18301 acggttgcaa aaacggcaaa ttgcttgttt tatggcacat taacggggct tttgctgaaa
    18361 aaatgcgcgg tcagaaaatt attttaaatt tcctcttgtc aggccggaat aactccctat
    18421 aatgcgccac cactgacacg gaacaacggc aaacacgccg ccgggtcagc ggggttctcc
    18481 tgagaatctc aac
//
LOCUS       DAZUDJ010000083        18353 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.083, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000083 DAZUDJ010000000
VERSION     DAZUDJ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18353
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.083"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            266..1318
                     /gene="yhiM"
                     /locus_tag="ACHY1N_004108"
     CDS             266..1318
                     /gene="yhiM"
                     /locus_tag="ACHY1N_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2776 domain-containing protein"
                     /protein_id="HFS4046316.1"
                     /translation="MNIYIGWLFKLIPLIMGLICIALGGFVLESSGQSEYFVAGHVLI
                     SLAAICLALFTTAFIIISQLTRGVNTFYNTLFPIIGYAGSIITMIWGWALLAGNDVMA
                     DEFVAGHVIFGVGMIAACVSTVAASSGHFLLIPKNAAGSKSDGTPVQAYSSLIGNCLI
                     AVPVLLTLLGFIWSITLLRSADITPHYVAGHVLLGLTAICACLIGLVATIVHQTRNTF
                     STKEHWLWCYWVIFLGSITVLQGIYVLVSSDASARLAPGIILICLGMICYSIFSKVWL
                     LALVWRRTCSLANRIPMIPVFTCLFCLFLASFLAEMAQTDMGYFIPSRVLVGLGAVCF
                     TLFSIVSILEAGSAKK"
     gene            complement(1634..2836)
                     /gene="yhiN"
                     /locus_tag="ACHY1N_004109"
     CDS             complement(1634..2836)
                     /gene="yhiN"
                     /locus_tag="ACHY1N_004109"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFS4046317.1"
                     /translation="MERFDAIIIGAGAAGMFCSALAGQAGRRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQWDFIDLVNKHGIAWHEKTLGQLF
                     CDDSAQQIVDMLVDECEKGNVTFRLRSEVLSVAKDETGFTLELNGMTVGCEKLVIATG
                     GLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITA
                     ENGIVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPN
                     QSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQALISTLTDWRVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLIAAKSS"
     gene            3068..4567
                     /gene="pitA"
                     /locus_tag="ACHY1N_004110"
     CDS             3068..4567
                     /gene="pitA"
                     /locus_tag="ACHY1N_004110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HFS4046318.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLI
                     VSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQ
                     HPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSL
                     DQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVL
                     SSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL"
     gene            complement(4638..4973)
                     /gene="uspB"
                     /locus_tag="ACHY1N_004111"
     CDS             complement(4638..4973)
                     /gene="uspB"
                     /locus_tag="ACHY1N_004111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HFS4046319.1"
                     /translation="MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYV
                     DGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVV
                     SLIALMIWH"
     gene            5364..5798
                     /gene="uspA"
                     /locus_tag="ACHY1N_004112"
     CDS             5364..5798
                     /gene="uspA"
                     /locus_tag="ACHY1N_004112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HFS4046320.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            complement(5897..5950)
                     /locus_tag="ACHY1N_004113"
     CDS             complement(5897..5950)
                     /locus_tag="ACHY1N_004113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046321.1"
                     /translation="MVLNVVLAGDFDCVRRS"
     gene            6116..7585
                     /gene="dtpB"
                     /locus_tag="ACHY1N_004114"
     CDS             6116..7585
                     /gene="dtpB"
                     /locus_tag="ACHY1N_004114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HFS4046322.1"
                     /translation="MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQ
                     LGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGMSL
                     LKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIAL
                     SLAPVIADRFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFRPMSFSKLLYVL
                     LGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLML
                     EAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVLASPILAGIYT
                     HLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLG
                     ELFISALGLAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLET
                     LPVYTNVFGKIGLVTLGVAVVMLLMVPWLKRMIATPESH"
     gene            complement(7634..8386)
                     /gene="rsmJ"
                     /locus_tag="ACHY1N_004115"
     CDS             complement(7634..8386)
                     /gene="rsmJ"
                     /locus_tag="ACHY1N_004115"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008990 - rRNA
                     (guanine-N2-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HFS4046323.1"
                     /translation="MQICLIDETGTGDGALSVLAARWGLEHDEDNLMALVLTPEHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTD
                     ITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVK
                     RPDYAPPLANVATPNAVVTKGHRFDIYAGTPV"
     gene            complement(8392..10434)
                     /gene="prlC"
                     /locus_tag="ACHY1N_004116"
     CDS             complement(8392..10434)
                     /gene="prlC"
                     /locus_tag="ACHY1N_004116"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HFS4046324.1"
                     /translation="MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQG
                     APYTWENLCQPLAEVDDVLGRIFSPVSHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFE
                     NYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVDELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDVDVWHPDVR
                     FFELYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFR
                     PDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     FSRFEEEGIFNRETGQSFLDNILSRGGSEEPMDLFKRFRGREPQLDAMLEHYGIKG"
     gene            10637..11479
                     /gene="rlmJ"
                     /locus_tag="ACHY1N_004117"
     CDS             10637..11479
                     /gene="rlmJ"
                     /locus_tag="ACHY1N_004117"
                     /EC_number="2.1.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase"
                     /protein_id="HFS4046325.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPL
                     IARQLLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGIAEGYKRFATGTYALWYPVVLRQQIKRMIHDLEATGIRK
                     ILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSW
                     IVPE"
     gene            11551..12903
                     /gene="gorA"
                     /locus_tag="ACHY1N_004118"
     CDS             11551..12903
                     /gene="gorA"
                     /locus_tag="ACHY1N_004118"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFS4046326.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENV
                     LGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGF
                     FALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTNAIPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAG
                     VKTNEKGYIVVDKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCVGSEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR
                     "
     gene            complement(12957..13040)
                     /gene="dinQ"
                     /locus_tag="ACHY1N_004119"
     CDS             complement(12957..13040)
                     /gene="dinQ"
                     /locus_tag="ACHY1N_004119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible type I toxin DinQ"
                     /protein_id="HFS4046327.1"
                     /translation="MIDKAIIVLGALIALLELIRFLLQLLN"
     gene            13068..13241
                     /locus_tag="ACHY1N_004120"
     CDS             13068..13241
                     /locus_tag="ACHY1N_004120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046328.1"
                     /translation="MHPLTHPLPVTAHALLLDNGILTPARASVNGTTRTSDQDFESVY
                     AHYQSENASELTG"
     gene            13549..13902
                     /gene="arsR"
                     /locus_tag="ACHY1N_004121"
     CDS             13549..13902
                     /gene="arsR"
                     /locus_tag="ACHY1N_004121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /protein_id="HFS4046329.1"
                     /translation="MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQ
                     PKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAKIIDEAWRCEQEKVQAIVRN
                     LARQNCSGDSKNICS"
     gene            13956..15245
                     /gene="arsB"
                     /locus_tag="ACHY1N_004122"
     CDS             13956..15245
                     /gene="arsB"
                     /locus_tag="ACHY1N_004122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite/antimonite:H(+) antiporter ArsB"
                     /protein_id="HFS4046330.1"
                     /translation="MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPG
                     DIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLG
                     AAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
                     NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAI
                     KDPATFKTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLR
                     GAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSI
                     MNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQ
                     KNMTISWGYYFRTGIIMTLPVLFVTLAALALRLSFTL"
     gene            15258..15683
                     /gene="arsC"
                     /locus_tag="ACHY1N_004123"
     CDS             15258..15683
                     /gene="arsC"
                     /locus_tag="ACHY1N_004123"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-dependent arsenate reductase"
                     /protein_id="HFS4046331.1"
                     /translation="MSNITIYHNPACGTSRNTLEMIRNSGTEPTIIYYLETPPTRDEL
                     VKLIADMGISVRALLRKNVEPYEELGLAEDKFTDDRLIDFMLQHPILINRPIVVTPLG
                     TRLCRPSEVVLEILPDAQKGAFSKEDGEKVVDEAGKRLK"
     gene            complement(15806..16102)
                     /locus_tag="ACHY1N_004124"
     CDS             complement(15806..16102)
                     /locus_tag="ACHY1N_004124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFS4046332.1"
                     /translation="MQLEEVAKALKELGHPTRLFIFKHLVKAGEQGLPVGELQKQLGI
                     PGSTLSHHISALVSVGLVKQNRESRTLMCVSQYAMLEAIIEFLREECCVNSKIA"
     gene            16210..17211
                     /locus_tag="ACHY1N_004125"
     CDS             16210..17211
                     /locus_tag="ACHY1N_004125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFS4046333.1"
                     /translation="MSSWLAMLQDAAEMFVFLAVELSLLFIVISAGVSLIRQKVPDHK
                     IQQMMGARKGRGYLLAALLGAVTPFCSCSTIPMLRGLLSAKAGFGPTLTFLFVSPLLN
                     PIIVGLMWMTFGWKVTLLYAIIAAGVSVLASIILDSLGFERHIIASKSSSANCCALAK
                     TSPGTTYTPIKVSCCSPAAKAIENPVVTCCSTKAVVSINPIKLATKDALQQFKDVLPY
                     LLLGVLIGSFIYGFIPSAWIAAHAGADNPFAIPLSAVVGIPLYIRAEAVIPLASVLMT
                     KGMGLGALMALIIGSAGASLTEVILLKSMFRMPMIAAFLTVILGMAILMGYLTQLLF"
     gene            17791..>18353
                     /locus_tag="ACHY1N_004126"
     CDS             17791..>18353
                     /locus_tag="ACHY1N_004126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046334.1"
                     /translation="MSIDFTPGIINTYHGDIYNCTTNTDNVKTPDTPKWPCDNWEEQQ
                     PINSIFSGEGYNPEQFDLAQQQLQQINACHTNTTYTNADYSKVVVQLVSLINNIETIS
                     STPLTQQTQSILNQINNIRYEKNKSAECRIIVVANPKPDKAIITKISVEEGIPITFSV
                     QTMFSDTNFIAEQRTDLPTNIKDIQSL"
BASE COUNT         4382 a         4661 c         4513 g         4797 t
ORIGIN      
        1 actatccggt cttttactaa ataatggaaa acaatccatc cctggaggat aattgtaaaa
       61 aaaacaacag aataagaatt aatcttagga taaatattta tttatcatgg ccttttaacc
      121 ggtaaaaaat ggcactcggc acagtaaacc ccgctatagt tatgctatgc atttgtcttt
      181 aatgatatct cgtcgttata ttaacaggct gaaattatca ttaatgcaca tttcattatt
      241 agcagggata cctgaggagt ttaaagtgaa catatatatc gggtggcttt tcaaattaat
      301 ccctttgatt atgggattaa tttgcatcgc gttaggtggc tttgtgctgg aaagttcagg
      361 gcaaagcgag tatttcgtcg cgggtcatgt gctgatttct ctggcggcca tatgcctggc
      421 attattcact accgcattta ttatcatttc gcagctcacg cgcggcgtta atacgtttta
      481 caatacattg ttccccatta ttggctatgc ggggtcaatt atcaccatga tatggggttg
      541 ggcactgtta gcaggcaatg atgtgatggc agacgagttt gtcgccggcc atgttatttt
      601 cggcgttggt atgattgccg cctgtgtatc gacggtggca gcgtcatccg gtcactttct
      661 gctcattccc aaaaatgcag cggggagcaa gagcgatgga acgccggtac aggcttattc
      721 ttcattaatc ggtaattgcc tcattgccgt tcccgtttta ctcaccctgc tcggtttcat
      781 ttggtctatt acgctgttac gtagtgctga cataactccg cattatgtcg cgggtcacgt
      841 attgcttggg ttaaccgcaa tctgtgcctg tctaattggc cttgttgcca caattgtcca
      901 tcaaacacgt aatacgtttt caactaaaga acactggctg tggtgttatt gggttatttt
      961 tctcggctca atcacggtac tgcaggggat atacgtctta gtcagttccg atgcaagcgc
     1021 ccgactggct cccggcatta ttcttatttg cctcggaatg atctgttaca gcatattctc
     1081 aaaagtctgg ctactggcac tggtatggag acgtacctgt tcgttagcca acagaatacc
     1141 gatgattccc gtcttcacct gcctgttttg ccttttcctg gcatcgtttc ttgcggaaat
     1201 ggcgcagacc gacatgggat attttattcc ttcgcgggtt ttggtcggtt taggagcggt
     1261 atgctttacg ttgttctcaa tcgtttcaat attagaagca ggttctgcta aaaaataatt
     1321 gcaacgtacc ggataaaacc agcgttgacc atttgcgtaa cgctggtttt tcttaggcat
     1381 catgaaataa cgcagcatta atgcatagtg gttaaggata aaaaaacaac aaagttactg
     1441 tttttttcaa cctgttcata ttttataaag ttctggccac tgggtgagtt ttcaatcacc
     1501 tttccttcca ccttatatta agcctggagg gtttcagttc acgggctcat tagaaaataa
     1561 tcacaagata gccactatca aaattagctc atttttaata cggctctaat aattttcatc
     1621 tttaggtaac aggtcaggac gacttcgctg caatcaaatc ctgcgcacaa gcccacgcac
     1681 tcgaccacgc ccactggaag ttatagcccc ccagccagcc ggtaacgtcc atcacttcgc
     1741 cgatgaagta cagcccaggc actttgcgcg cttccatcgt ccgtgaagag agttcgttgg
     1801 tgtccacgcc gccgagcgtc acttcggcag tgcgatagcc ttcagtgccg ttgggttgta
     1861 cgcgccagtc ggtcaatgtg ctaatcagtg cctgttggtc acgcacgttg agctgtttta
     1921 gcgaaacatc cgggatttgc ccgagttgct gtaagcgttc aaccaaccgc ttcggtagat
     1981 gaaccgccag tgtgtttttc aggctctgat tcggatgtgc gttacgctgc tcattcagga
     2041 aggtttcgag atccacatcc ggtagcagat tgatactgac aaattcaccc ggttgccagt
     2101 agctggaaat ctgcaacacc gccggtccag acaagccgcg atgggtgaag agtaagttct
     2161 cacggaaaac gatgccgttt tcagcggtaa tcacggaagg caccgccacg cccgccagca
     2221 cctgtaactc ttcgagcaac ggtttatgca gagtgaatgg caccagaccc gcgcgggtcg
     2281 gcagcacgtt gaggccaaat tgttcggcaa tcttataacc aaacggcgac gcgcccagcc
     2341 ccggcattga cagcccaccg gtcgcgatga ccagcttttc gcaaccgaca gtcatgccgt
     2401 tcagttcaag cgtgaagcct gtttcatcct tcgccacact cagcacttcg ctacgcaatc
     2461 tgaaggttac attgcccttc tcgcactcat ccaccagcat gtcgacaatc tgctgcgcgg
     2521 agtcatcgca gaagagttgt cctaacgttt tctcgtgcca ggcgatgccg tgtttattga
     2581 ccagatcaat gaaatcccac tgggtaaaac gcgcgagtgc agacttacaa aaatgcggat
     2641 tctggctcag ataagcgcct ggttcgacat aaaggttggt aaagttgcag cgcccaccgc
     2701 cagacataag gattttgcgc cctggttttt taccattatc gatcagcaga acccggcgtc
     2761 ctgcctgacc tgccagcgca gaacagaaca tacccgccgc accagcgcct ataataatgg
     2821 catcaaacct ttccacgttg cgctcctctt agaaaaaacg ggcgtgaatt gtaaagattc
     2881 ctcagtggtc gcaccagcat caatattact aaaaggaagt atttgcctga attatataag
     2941 ataattattt tttgagtgaa atccatacag gaggcaaatc aaaaaaagtc tatatttcac
     3001 tttgcccgcg ccgcgaaagt cactgataat gcgccgcgtt catgtcctca aaatggcgta
     3061 acgtcctatg ctacatttgt ttgctggcct ggatttgcat accgggctgt tattattgct
     3121 tgcactggct tttgtgctgt tctacgaagc catcaatggt ttccatgaca cagccaacgc
     3181 cgtggcaacc gttatctata cccgcgcgat gcgttctcag ctcgccgtgg ttatggcggc
     3241 ggtgttcaac tttttgggtg ttttgctggg tggtctgagt gttgcctatg ccattgtgca
     3301 tatgctgccg acggatctgc tgcttaatat gggatcgtct catggccttg ccatggtgtt
     3361 ctctatgttg ctggcggcga ttatctggaa cctgggtacc tggtactttg gtttacctgc
     3421 atccagctct catacgctga ttggcgcgat catcgggatt ggtttaacca atgcgttgat
     3481 gaccgggacg tcagtggtgg atgcactcaa tatcccgaaa gtattaagta ttttcggttc
     3541 tctgatcgtt tcccctattg tcggcctggt gtttgctggc ggtctgattt tcttgctgcg
     3601 tcgctactgg agcggcacca agaaacgcgc ccgtatccac ctgaccccag cggagcgtga
     3661 aaagaaagac ggcaagaaaa agccgccgtt ctggacgcgt atcgcgctga tcctttccgc
     3721 tatcggcgtg gcgttttcgc acggcgcgaa cgatggtcag aaaggcattg gtctggttat
     3781 gttggtattg attggcgtcg cgccagcagg cttcgtggtg aacatgaatg ccactggcta
     3841 cgaaatcacc cgtacccgtg atgccatcaa caacgtcgaa gcttactttg agcagcatcc
     3901 tgcgctgctc aaacaggcta ccggtgctga tcagttagta ccggctccgg aagctggcgc
     3961 aacgcaacct gcggagttcc actgccatcc gtcgaatacc attaacgcgc tcaaccgcct
     4021 gaaaggtatg ttgaccaccg atgtggaaag ctacgacaag ctgtcgcttg atcaacgtag
     4081 ccagatgcgc cgcattatgc tgtgcgtttc tgacactatc gacaaagtgg tgaagatgcc
     4141 tggcgtgagt gctgacgatc agcgcctgtt gaagaaactg aagtccgaca tgcttagcac
     4201 catcgagtat gcaccggtgt ggatcatcat ggcggtcgcg ctggcgttag gtatcggtac
     4261 gatgattggc tggcgccgtg tggcaacgac tatcggtgag aaaatcggta agaaaggcat
     4321 gacctacgct caggggatgt ctgcccagat gacggcggca gtgtctatcg gcctggcgag
     4381 ttataccggg atgccggttt ccactactca cgtactctcc tcttctgtcg cggggacgat
     4441 ggtggtagat ggcggcggct tacagcgtaa aaccgtaacc agtattctga tggcctgggt
     4501 gtttaccctt ccggctgcgg tactgctttc cggcggactg tactggctct ccttgcagtt
     4561 cctgtaatcg tacacaccaa aacgagcggg tcagtttact ggcccgcttt ttttatgcgt
     4621 tattattgct gaagtgctta atgccaaatc atcaatgcaa tcaggctgac caccaccaga
     4681 ccacacaatg cgctggtcag aataaactgc cgacgcaccc gctcacagcg gcgaataaat
     4741 tcatcatcgt gatgatcgcg ataacgttgg gcatagatat accaaacgag acgcacctgt
     4801 ttgttgggtt ggccatgtga ggtaaaaaag ccccctccat caacatattg atagagcaat
     4861 ggatcgcagt tacgcagtac cactaacaac gcgcgtagtg atgagaaata gcgcgccatg
     4921 ttaacaatgc aaacgacaca taaagcccaa aataatgcga cggtgcttat catacctcct
     4981 ccccggcgac ctgcccgcgg agttccaccc cggggctacc gctcccgata cgctgccaat
     5041 cagttaacac caggtcctgg agaaaccgct tttgtggtga ccaacatccg agcggctcta
     5101 tagatagtgt aggagatcag gttgtttttt ttccagaagg ttaaccacta tcaatatatt
     5161 catgtcgaaa atttgtttat ctaacgggta agcaaggcgg attgacggat catccgggtc
     5221 gctataaggt aaggatggtc ttaacactga atctttacgg ctgggttagc cccgcgcacg
     5281 tagttcgcag gacgcgggtg acgtaacggc acaagaaacg ctagctggcc agtcatcgac
     5341 aactttatgg aaggagtaac actatggctt ataaacacat tctcatcgcg gtcgatctct
     5401 ccccggaaag caaagttctg gtagagaaag cagtctctat ggctcgcccc tacaatgcga
     5461 aagtttctct gatccacgta gatgtaaact actctgacct atacaccggg cttattgatg
     5521 tgaatctggg tgatatgcag aaacgcatct ctgaagagac acatcatgcg ctgaccgagc
     5581 tttccactaa tgcaggctac ccaatcactg aaaccctgag cggcagcggc gacctgggcc
     5641 aggttctggt cgatgcaatc aagaaatacg atatggatct ggtggtttgt ggtcaccacc
     5701 aggacttctg gagcaaacta atgtcttccg cacgtcagct gatcaacacc gttcacgttg
     5761 atatgctgat tgttccgctg cgcgacgaag aagaataatc atccccccac gacgtgttcc
     5821 tgaacgcccg catatgcggg cgttttgctt tttggcgcgc cttgttacct gatgcagcgt
     5881 aaacccctta tctggcctac gatctgcgta cgcaatcaaa atctcctgcc aatacaacat
     5941 ttaacaccat catattttcc atcattagtg tgatcagctg gttattttct gttgtaatag
     6001 tgtattaatc tattcaccac atcaatatta agaatctctg acagatgtaa actttttcgc
     6061 gcgttatccc ttacgcgttc atacttttca ggatggtatt ggaaggttaa taaatatgaa
     6121 tacaacaaca cccatgggga tgctgcagca acctcgccca tttttcatga tcttttttgt
     6181 cgagttatgg gagcgattcg gctactacgg cgtgcagggc gtactggcgg ttttcttcgt
     6241 taaacagctt ggattctcgc aagagcaggc ttttgtcact tttggtgctt ttgctgcgct
     6301 ggtctatggc ctcatttcca ttggcggcta tgtcggcgac cacctgctgg ggaccaaacg
     6361 caccattgtt ctcggagcac ttgtgctggc gattggctac ttcatgaccg gcatgtcgct
     6421 acttaagcct gacctgattt tcatcgccct ggggactatc gctgtcggta acggcctgtt
     6481 taaagctaac ccagccagct tgctttcgaa gtgctatccg ccgaaagatc cgcggcttga
     6541 tggcgcattc accctgttct atatgtcgat caatatcggc tcgttgatag cgttatcgct
     6601 ggcccctgtg atcgctgata gattcggtta ttcagtcacc tacaacctgt gcggggcggg
     6661 gttaattatc gcattactgg tttacatcgc ctgtcgtgga atggtgaaag acattggttc
     6721 tgaacccgac ttccggccaa tgagcttcag caaactgttg tacgtgttac ttggcagcgt
     6781 ggtgatgatc ttcgtctgtg catggctgat gcacaacgta gaagtcgcca atctggtgct
     6841 gattgttctc tccatcgtcg tcaccatcat cttctttcgt caggcattca agctggataa
     6901 aaccgggcgc aataaaatgt ttgtcgcctt tgtcctgatg ctcgaagcgg tggtgtttta
     6961 cattctctac gcccagatgc caacgtcgct gaacttcttt gccatcaaca acgtgcatca
     7021 tgaaattctc ggcttttcca tcaacccggt cagcttccag gcgcttaacc cgttctgggt
     7081 ggtactcgcc agcccaatac tggcaggcat ttacacgcat ctgggtaaca aaggcaaaga
     7141 cctctcgatg ccgatgaaat ttactctcgg catgtttatg tgctcactgg gctttttgac
     7201 ggcggcagct gcgggaatgt ggtttgctga tgcacaagga ctgacatcgc cgtggtttat
     7261 cgtgctggtt tacttgttcc agagcctggg tgaattgttt attagcgccc tgggtctggc
     7321 gatgattgct gccctggtgc cgcagcattt gatgggcttt attctcggga tgtggttcct
     7381 gacgcaggct gccgcgttct tgctgggcgg ctatgtggca acatttaccg cggtgccgga
     7441 caacattacc gatccgcttg agacgttgcc cgtctatacc aacgtgtttg gtaagattgg
     7501 tctggtcacg ctgggcgttg cagtagtgat gctgttgatg gtgccgtggc tgaaacgcat
     7561 gattgcgacg ccggaaagcc attaattatt cttgcagaaa gcagggtagc gttatcgcta
     7621 ccctgcttta cttttacacc ggcgttccgg cataaatatc aaacctatgc cctttagtga
     7681 ctaccgcgtt tggcgtggcg acattcgcca gcggtggcgc gtagtccggg cgctttacca
     7741 ccacgcgttt ggtcgccagc agccgcgcag gctccagcaa tccatcggca tcaagatccg
     7801 gccccaccag cgactgaaag acacgcatct cttttttcac cagcgcgctt ttctgcttat
     7861 gcgggaacat cgggtcgaga taaaccacct gcgggcgcgg ggtaatatca gtcagcgccg
     7921 tcaggctgga ggcgtgaatt aactgcaacc gctcctgcaa ccagccgccg atttccgcat
     7981 ccgcataacc acgcgccagg ccgtcgtcga gcaaggcggc aacgactgga ttacgctcca
     8041 gcatccgcac gcggcaaccg actgaagcca gcacaaaggc atcgcgcccc agccctgcgg
     8101 tggcgtccac cacatccggc aaataatcgc ctttaatgcc caccgctttc gccaccgcct
     8161 caccgcgacc accgccgaat ttgcgtcggt gcgccatcgc tccgccaaca aaatcaacaa
     8221 agatgccgcc aagttttggc tcatcacgct tgcgcaattc cagatgttcc ggcgttaaca
     8281 ccagcgccat caggttgtct tcatcgtgct ccagccccca gcgggccgcc agaacagata
     8341 aggcaccgtc tccggtgcct gtttcatcaa ttaagcaaat ctgcacaaaa actaaccttt
     8401 gatcccgtaa tgctccagca tcgcatccag ctgcggctca cgaccacgga agcgtttgaa
     8461 cagatccatc ggctcctctg aaccgccacg gctcagaatg ttgtcgagga acgactgccc
     8521 ggtttcacgg ttgaaaatgc cctcttcctc aaagcgcgag aaagcatctg ccgccagtac
     8581 gtcagcccac aggtagctgt agtaacctgc ggcataacca ccggcgaaaa tatggctgaa
     8641 agcgtgcggg aaacggcccc aggatggaga cggtactacg gcaaccagtt tcttgatttc
     8701 tgccagagtt tcgaggattt tcgctccctg atccgggcgg aactcggcat ggaggcggaa
     8761 atcgaacagg ccgaactcca gctggcgcag aataaacagc gccgcctggt agttcttcgc
     8821 cgccagcatt ttatccagca actctttcgg cagcggttcg ccggtttcgt agtgaccaga
     8881 gataaacgcc agcgcctcag gctcccagca ccagttttcc ataaactgac tcggcagttc
     8941 gaccgcatcc cacggcaccc cactgatccc ggatacaccg gcggtttcga tgcgggtcag
     9001 catatgatgc agaccatgac cgaactcgtg gaacagggtg atcacttcgt catgggtaaa
     9061 cagcgccggt ttaccattta ccgggcggtt aaagttacag gtcagatacg cgaccggttt
     9121 ttgcagagaa ccgtcagctt tgcgcatctg gcctacgcag tcatccatcc acgccccgcc
     9181 gcgcttgttt tcacgggcat acaggtcgag gtagaagcta ccgcgcagtt cgttgttctc
     9241 gtcatacagt tcgaagaaac gtacatccgg gtgccagaca tcaacatctt tacgctcttt
     9301 agcggtgatg ccgtaaatac gtttcaccac ttcaaacaaa ccgttaaccg ctttgttttc
     9361 cgggaagtac ggacgcagct gttcgtcact gatgctgtag aggtgctgtt tttgtttttc
     9421 gctgtagtac gcgatatccc acggctgcaa ctcatcgacg ccaaattcgg ctttggcaaa
     9481 ggcgcgcagt tgtgccagct ctttttcgcc ttgcggacgc gcgcgttttg ccagatcggt
     9541 taagaaatcc agcacctgct gcgggttttc tgccatttta gtggcaaggg atttaaaggc
     9601 gtagttttca aagcccagca gttgcgccag ttcgtgacgc agcgcgagga tctcttccat
     9661 caccttgctg ttgtcccact taccggcgtt cggaccttga tcggaggcgc gggtgctgta
     9721 agcgcgatac atctcttcac gcagagcctg gttgtcgcag taggtcatta ccggcaggta
     9781 gcttgggata tccagcgtca gcaggtagcc ttcaagttct ttcgcttcag cctgggcttt
     9841 tgccgcagcc agcgcgcttt ctggcatccc cgccagttcc gcttcgtcgg taacgagttt
     9901 ggtccagccc attgtcgcat cgaggacgtt gttgctgtac tggttgccca gttcagaaag
     9961 acgggtagca atttcgccgt aacgctgctg tttctctttc ggcagaccta tgccagagag
    10021 ttcaaaatca cgcagggcgt tatcaaccgc tttcttctgc gccgtgttca gcgtggcgta
    10081 atgatcgcca tcgcgcaggt cgcggtacgc tttatacagc ccttcatgtt gccctaccca
    10141 ggtgctgtat tccgacagca gcggcagggt ttgttcgtac gcttcacgca gttccgggct
    10201 atttttcacc gagttcaggt ggctgaccgg ggagaagata cgccccaaca catcgtccac
    10261 ttccgccaac ggctggcaga gattttccca ggtgtacggt gccccttgcg ctactacgcg
    10321 ctccacgttt tcgcggcagt cgttcaatgc cttagtcacg gctggaacga catgttccgg
    10381 gagaatttta gaaaacggag gcaattcaaa gggagtcagt aacggattcg tcattcgcgc
    10441 agtcctggtt aaagaggtta aggaagcgct caacaggcgc tttacataat gtgtgtagca
    10501 tggggttaag tgtagtgaat ttcaatgaga aacgttacgc tttcgcggcg gcggcctctt
    10561 ttcggtatac tgtcctgata cgcttttgtg cgccccgaat acgggccgat ttttacttac
    10621 cggaacacct ttacccatgc tcagttatcg ccacagcttt cacgctggca accacgccga
    10681 cgtccttaaa cataccgttc agagcctgat catcgagtcg ctgaaagaga aagataaacc
    10741 gtttctctat ctcgacaccc acgcaggggc cgggcgttat cagttaggca gcgaacatgc
    10801 cgagcgtacc ggcgaatatc tcgaaggcat cgcccgtatc tggcagcagg acgatttgcc
    10861 cgcagaactg gaggcgtaca tcaatgtggt aaaacacttc aaccgtagcg gtcagttgcg
    10921 ttactacccc ggttcgccgt tgattgctcg ccagctactg cgcgaacaag acagcctgca
    10981 actgaccgaa ctgcacccga gcgattaccc gttgctgcgt tctgaatttc agaaagacag
    11041 ccgtgcgcgc gtcgaaaaag ccgatggttt ccagcagctt aaggccaaac tgccgccggt
    11101 ttcccgccgt ggtttaatcc ttatcgaccc gccgtatgaa atgaaaaccg actatcaggc
    11161 ggtggtcagc gggatagcag aaggttacaa acgtttcgcc actggtactt acgcactgtg
    11221 gtatccggtg gtgctgcgtc agcaaattaa gcgcatgatc cacgatctgg aagcgaccgg
    11281 tattcgcaaa attctgcaaa ttgaactggc ggtactgcca gacagcgatc gccgtggcat
    11341 gaccgcttcc ggcatgattg tgattaaccc gccgtggaaa ctggaacaac agatgaataa
    11401 cgtgctgccg tggctgcaca gcaaactggt tccggcaggc accgggcacg ccaccgtaag
    11461 ctggatcgtg ccggagtaat tgcagccatt gctggcacct attacgtctc gcgctacaat
    11521 cgcggtaatc aacgataagg acactctgtc atgactaaac actatgatta catcgccatc
    11581 ggcggcggca gcggcggtat agcctccatc aaccgcgcgg ctatgtacgg ccagaaatgc
    11641 gcactgattg aagccaaaga gctgggcggc acctgcgtga acgtcggctg tgtgccgaaa
    11701 aaagtgatgt ggcacgcggc gcaaatccgt gaagcgatcc atatgtacgg cccggattat
    11761 ggttttgata ccactatcaa taaattcaac tgggaaacgt tgatcgccag ccgtaccgcc
    11821 tatatcgacc gtattcatac ttcctatgaa aacgtgctcg gtaaaaataa cgttgatgta
    11881 atcaaaggct ttgcccgctt cgttgatgcc aaaacgctgg aggtaaacgg cgaaaccatc
    11941 acggccgatc atattctgat cgccacaggc ggtcgtccga gccacccgga tattccgggc
    12001 gtggaatacg gtattgattc tgatggcttc ttcgcccttc ctgctttgcc agagcgcgtg
    12061 gcggttgttg gcgcgggtta catcgccgtt gagctggcgg gcgtgattaa cggcctcggc
    12121 gcgaaaacgc atctgtttgt gcgtaaacat gcgccgctgc gcagcttcga cccgatgatt
    12181 tccgaaacgc tggtcgaagt gatgaacgcc gaaggcccgc agctgcacac caacgccatc
    12241 ccgaaagcgg tagtgaaaaa tgccgatggt agcctgacgc tggagctgga agatggtcgc
    12301 agtgaaacgg tggattgcct gatttgggcg attggtcgcg agcctgccaa tgacaacatc
    12361 aacctggaag ccgctggcgt taaaactaac gaaaaaggct atatcgtcgt cgataaatat
    12421 caaaacacca atattgaagg tatttacgcg gtgggcgata acacgggtgc agtggagctg
    12481 acaccggtgg cagttgcagc gggtcgccgt ctctctgaac gcctgtttaa taacaagccg
    12541 gatgagcatc tggattacag caacattccg accgtggtct tcagccatcc gccgattggt
    12601 actgttggtt taacggaacc gcaggcgcgc gagcagtatg gcgacgatca ggtgaaagtg
    12661 tataaatcct ctttcaccgc gatgtatacc gccgtcacca ctcaccgcca gccgtgccgc
    12721 atgaagctgg tgtgcgttgg atcggaagag aagattgtcg gtattcacgg cattggcttt
    12781 ggtatggacg aaatgttgca gggcttcgcg gtggcgctga agatgggtgc aaccaaaaaa
    12841 gacttcgaca ataccgtcgc cattcaccca acggcggcag aagagttcgt gacaatgcgt
    12901 taaatgttaa agggctaaga gtagtgtgct cttagccctt aattacgttt ccgctatcag
    12961 ttcagaagct gaagcagaaa gcggatcagt tccagcagcg caattaacgc cccaagaacg
    13021 atgattgctt tatcaatcac ccgttttctc catgcgatgg agtgagaatg catccgctta
    13081 ctcatccact gcctgtcacg gcgcatgccc tattgttaga taatggcatt ctcactccgg
    13141 ccagagcatc agttaacggc accacccgta cttctgacca ggactttgaa agcgtttatg
    13201 cgcattacca gagtgaaaat gcctcagagc taactggata atcatacagt acattcaggt
    13261 tataaaacca gcatgtcctt gcaatagttt cagtatggta ttagcattga tgcgttagat
    13321 aatggcattc tcactccagc cagtgccacc aactcagggc tggaaagtaa aaaaccgacg
    13381 caaagtcggt ttttttacgt cctgattcag acctcctttc aaatgaatag ccaactcaaa
    13441 attcacacct attaccttcc tctgcactta cacattcgtt aagtcatata tgtttttgac
    13501 ttatccgctt cgaagagaga cactacctgc aacaatcagg agcgcaatat gtcatttctg
    13561 ttacccatcc aattgttcaa aattcttgct gatgaaaccc gtctgggcat cgttttactg
    13621 ctcagcgaac tgggagagtt atgcgtctgc gatctctgca ctgctctcga ccagtcgcag
    13681 cccaagatct cccgccacct ggcattgctg cgtgaaagcg ggctattgct ggaccgcaag
    13741 caaggtaagt gggttcatta ccgcttatca ccgcatattc cagcatgggc ggcgaaaatt
    13801 attgatgagg cctggcgatg tgaacaggaa aaggttcagg cgattgtccg caacctggct
    13861 cgacaaaact gttccgggga cagtaagaac atttgcagtt aaaaatttag ctaaacacat
    13921 atgaattttc agatgtgttt tatccgggag gcattatgtt actggcaggc gctatctttg
    13981 tcctgaccat cgtattggtt atctggcagc cgaaaggttt aggcatcggc tggagtgcaa
    14041 cgctcggcgc agtactggcg ttagttacgg gcgtggtcca tccgggtgat attccggtgg
    14101 tgtggaatat cgtctggaac gcgacggctg cgtttatcgc cgtcattatc atcagcctgc
    14161 tgctggatga gtccggcttt tttgaatggg cggcgctgca cgtctcacgc tggggtaatg
    14221 gtcgtggtcg cttgctgttt acctggattg tcctgctcgg tgctgccgtt gccgccctgt
    14281 ttgccaatga tggcgcggcg cttattttga caccgattgt catcgccatg ctgctggctt
    14341 tagggttcag taaaggcact acgctggcgt tcgtgatggc ggccggattc attgccgata
    14401 ccgccagcct gccgcttatt gtctccaacc tggtgaatat cgtttccgct gatttctttg
    14461 gcctcggctt tcgcgaatac gcctcggtga tggtgccggt ggatatcgcc gcgattgttg
    14521 ccacgctggt gatgttacat ctctattttc gcaaagatat tccgcagaac tacgatatgg
    14581 cgctgctgaa atctcccgca gaagcgatca aagatcctgc tacgttcaaa actggctggg
    14641 ttgttttact gcttctgctg gtgggatttt tcgtcctgga accgctcggc attccggtga
    14701 gcgccattgc agctgtgggc gcgctgatat tatttgtcgt cgctaaacgc ggtcatgcga
    14761 ttaatacggg taaagtcctg cgcggtgccc cctggcagat tgtcatcttc tcgctcggca
    14821 tgtatctggt ggtttatggc ctgcgcaatg ccggattaac ggaatatctt tctggcgtac
    14881 tcaacgtgct ggcggataac ggcctgtggg ccgcgacgct cggcaccgga ttcctcaccg
    14941 ccttcctctc ttctattatg aacaatatgc cgacggtact ggttggcgcg ttgtccattg
    15001 atggcagcac ggcatctggc gttatcaaag aagcgatggt ttatgccaat gtgattggct
    15061 gcgatttggg accgaaaatt accccaattg gtagcctggc tacgctactc tggctgcacg
    15121 tactttcgca gaagaatatg actatcagct ggggatatta cttccgtaca gggattatca
    15181 tgaccctgcc ggtgcttttt gtgacgctgg ctgcgctggc gctacgtctc tctttcactt
    15241 tgtaatgaga tattgatatg agcaacatta ccatttatca caacccggcc tgcggtacgt
    15301 cgcgtaatac gctggagatg atccgcaaca gcggtacaga accgaccatt atctattatc
    15361 tggaaacacc gccaacgcgc gatgagctgg tcaaactcat tgccgatatg gggatttccg
    15421 tacgcgcgct gttgcgtaaa aacgtcgagc cgtatgagga actgggcctt gcagaagata
    15481 aatttactga cgatcggtta atcgacttta tgcttcagca cccgattctg attaatcgcc
    15541 cgattgtggt gacgccgctg ggaactcgcc tgtgccgccc ttcagaagtg gtgctggaaa
    15601 ttctgccaga tgcgcaaaaa ggcgcattct ccaaggaaga tggcgagaaa gtggttgatg
    15661 aagcgggtaa gcggttgaaa taaagcggcg atatccactg cccatagttg gtaaagtgcg
    15721 ctttgtttat gtcggatgcg acgctaacgc gtcttatccg acctacaaaa ccgtgcatgg
    15781 catgaaatct gtagcgcgta gcgcatcagg caattttgct atttacgcag cactcctcgc
    15841 gtaagaattc aattatcgct tccagcattg cgtattgcga aacacacatc agcgtccgac
    15901 tctcacggtt ttgtttaacc agccctaccg ataccagtgc tgaaatatgg tgactgagtg
    15961 tagagccggg tatcccaagc tgcttttgca actcaccgac cggcaaacct tgctcccccg
    16021 ctttgaccag gtgtttgaat atgaacaaac gggtcgggtg acctagctct ttcagcgctt
    16081 tagcaacttc ttccaactgc atatgacacc ccctttgtct ggttgatatt tcgataatac
    16141 cagaaatatc ttgatctgaa tttcatttcg attattctgg aaatatagat ttatccaatg
    16201 aggttacgta tgagtagttg gcttgcgatg ctgcaagatg ccgcagagat gtttgtgttt
    16261 ctcgccgtcg agctttcgtt gctgtttata gtgattagtg ccggtgtcag cctgataaga
    16321 caaaaggtgc cagaccataa aatccagcag atgatggggg ccagaaaagg gagaggctat
    16381 ctcctggctg ctctgttggg agccgttacc ccgttctgta gttgctcgac aatacccatg
    16441 ttacgtggat tgttgtcagc gaaagccggg tttggtccga ctctcacttt tttatttgtt
    16501 tcaccattac ttaatcccat tatcgtcgga ctaatgtgga tgacctttgg ttggaaagtc
    16561 accttgttgt acgcgattat cgccgccggc gtctccgttc ttgccagtat tatcctggat
    16621 tctctggggt ttgaacgtca tatcattgcc agtaaaagct catcagcaaa ttgttgtgct
    16681 ctagcaaaaa cttcgccggg aacgacatat acgcccataa aagtgagttg ttgtagtcca
    16741 gcggctaaag ccattgagaa ccccgtagtt acctgttgca gtaccaaagc tgtagtaagt
    16801 attaatccca taaaactagc caccaaagat gcgttgcaac agtttaaaga tgtactgcca
    16861 tatcttttgt taggagtatt aataggatct tttatttatg gctttattcc ctcagcgtgg
    16921 attgccgctc atgcaggagc agataatccc ttcgccatcc cattaagcgc cgttgtcggt
    16981 attccgctgt atatccgggc tgaggcagtt atccctctgg catctgttct gatgacaaaa
    17041 ggaatgggtc tgggagcatt aatggcatta atcatcggca gtgccggcgc aagcctgacg
    17101 gaagtgatat tacttaaatc aatgttcaga atgccgatga tagctgcatt cctgacggtt
    17161 atattaggta tggctatctt gatgggctat ttgactcaat tgctatttta aatagatgcc
    17221 agcagtaaac tataagatgc atagttagtg ccatatcctt ctaagtagaa aatcatagac
    17281 aggataatcc ttaaaaatca caaatgattt aactaatgca ttgagaatga tgacggctcg
    17341 gtcaacaagt catcaacaga caataaccac gtaatcatgc ttctctgaca ttttatcgga
    17401 gaagcaatga ctctttgtct cagtaccctc ctccttttta aaaggcagat ttcagtcgct
    17461 aatacaacac atttttaaat acactttaac ctggttcatt attacacatc taaaacatca
    17521 caaaaatatt acttcacaca ctatcggaga acataataac tttttaaaat gagcgctttt
    17581 tgatagttgt taacgttttc ctttacgata ctatcactgc ctttttttat acacaaatat
    17641 taccgggtgg aaatgaaagg gaatttaaag gtaattatat caggaagata taacgcatta
    17701 tatttattgt gtgtagaaga aaatccattc ctgttctaat tattcaattt aaaaacctta
    17761 gcataaaaca gatgatgaat aaggaatgtt atgtcaattg actttacccc aggtataata
    17821 aatacatatc acggcgatat ttataactgc acaacaaata ccgataatgt taaaacgcca
    17881 gacacaccga agtggccttg tgataattgg gaagaacaac aacccattaa ttccatattc
    17941 tctggagaag gatacaaccc tgaacaattt gatttagcgc aacaacaact ccaacaaatt
    18001 aatgcatgcc acacgaacac cacatataca aatgcagact actcaaaagt tgtggttcaa
    18061 cttgtaagtc ttattaataa cattgaaacg ataagttcga caccacttac gcaacagaca
    18121 caatcaatac ttaatcagat taataacatt agatatgaaa aaaacaaaag tgctgaatgt
    18181 cgaatcattg ttgtcgctaa tcctaaaccc gacaaggcaa tcataactaa aattagcgta
    18241 gaagagggaa tacccataac attcagtgtc caaaccatgt tttcagatac taattttatt
    18301 gctgaacaac gaactgactt accaactaat ataaaagata ttcaaagcct gta
//
LOCUS       DAZUDJ010000084        18240 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.084, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000084 DAZUDJ010000000
VERSION     DAZUDJ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18240
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.084"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(266..1000)
                     /gene="cysH"
                     /locus_tag="ACHY1N_004127"
     CDS             complement(266..1000)
                     /gene="cysH"
                     /locus_tag="ACHY1N_004127"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004604 - phosphoadenylyl-sulfate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0019379 - sulfate assimilation,
                     phosphoadenylyl sulfate reduction by
                     phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HFS4046335.1"
                     /translation="MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNL
                     PGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLK
                     VYRATESAAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTT
                     RKWEPGMSEEETRFFGLKRECGLHEG"
     gene            complement(1074..2786)
                     /gene="cysI"
                     /locus_tag="ACHY1N_004128"
     CDS             complement(1074..2786)
                     /gene="cysI"
                     /locus_tag="ACHY1N_004128"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009337 - sulfite reductase complex
                     (NADPH) [Evidence IEA];
                     GO_function: GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HFS4046336.1"
                     /translation="MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKF
                     AGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPI
                     RPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRI
                     TANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERF
                     LPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGN
                     RIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DLWD"
     gene            complement(2786..4585)
                     /gene="cysJ"
                     /locus_tag="ACHY1N_004129"
     CDS             complement(2786..4585)
                     /gene="cysJ"
                     /locus_tag="ACHY1N_004129"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA];
                     GO_process: GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HFS4046337.1"
                     /translation="MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVL
                     NQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYK
                     FKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEF
                     FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSV
                     ATGAVNEIHSSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDAL
                     GVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYAT
                     LTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIAS
                     SQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPAN
                     PETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKD
                     GVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQAL
                     LEVIAEFGGMDTEAADEFLSELRVERRYQRDVY"
     gene            4904..5266
                     /gene="queD"
                     /locus_tag="ACHY1N_004130"
     CDS             4904..5266
                     /gene="queD"
                     /locus_tag="ACHY1N_004130"
                     /EC_number="4.1.2.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708563.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HFS4046338.1"
                     /translation="MSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEV
                     DPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLL
                     SAVMVKETCTAGCIYRGE"
     gene            5344..6615
                     /gene="ygcN"
                     /locus_tag="ACHY1N_004131"
     CDS             5344..6615
                     /gene="ygcN"
                     /locus_tag="ACHY1N_004131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417246.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4046339.1"
                     /translation="MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNL
                     SGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRA
                     RFDPWLVAEAEEEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
                     AERHGLVTRPAGEAMALGIKEVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGA
                     FLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVP
                     EGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHRE
                     PQNLFALYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKP
                     VPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL"
     gene            6606..6866
                     /gene="ygcO"
                     /locus_tag="ACHY1N_004132"
     CDS             6606..6866
                     /gene="ygcO"
                     /locus_tag="ACHY1N_004132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311649.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HFS4046340.1"
                     /translation="MSVAHNLWRVADAPHIVPADSVERQMVQRLINACPAGLFSLTPE
                     GDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG"
     gene            6883..7458
                     /gene="ygcP"
                     /locus_tag="ACHY1N_004133"
     CDS             6883..7458
                     /gene="ygcP"
                     /locus_tag="ACHY1N_004133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HFS4046341.1"
                     /translation="MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTIS
                     NIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGF
                     FCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVC
                     DEEDARNAINAGVVALSTTNTGVWTLAKKLL"
     gene            complement(7606..8466)
                     /gene="ygcQ"
                     /locus_tag="ACHY1N_004134"
     CDS             complement(7606..8466)
                     /gene="ygcQ"
                     /locus_tag="ACHY1N_004134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417249.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFS4046342.1"
                     /translation="MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQV
                     LDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHW
                     GNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNV
                     TRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISG
                     HLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEA
                     LVTNIHADCQ"
     gene            complement(8463..9242)
                     /gene="ygcR"
                     /locus_tag="ACHY1N_004135"
     CDS             complement(8463..9242)
                     /gene="ygcR"
                     /locus_tag="ACHY1N_004135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417250.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HFS4046343.1"
                     /translation="MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADE
                     QAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPE
                     FVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFI
                     TLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPA
                     MQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP"
     gene            complement(9220..10629)
                     /gene="ygcS"
                     /locus_tag="ACHY1N_004136"
     CDS             complement(9220..10629)
                     /gene="ygcS"
                     /locus_tag="ACHY1N_004136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4046344.1"
                     /translation="MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRI
                     AALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWIS
                     DHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGISLGGDYSVGHTLLAEFS
                     PRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWG
                     TPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFN
                     SVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHR
                     KFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIR
                     SLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKA
                     LPLVAAGNVGGANEHSVSV"
     gene            complement(10651..12105)
                     /gene="ygcU"
                     /locus_tag="ACHY1N_004137"
     CDS             complement(10651..12105)
                     /gene="ygcU"
                     /locus_tag="ACHY1N_004137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HFS4046345.1"
                     /translation="MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHG
                     IYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDG
                     SAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
                     IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITE
                     VTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHF
                     ADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVA
                     AERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQ
                     NGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWS
                     KLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK"
     gene            complement(12175..12960)
                     /gene="ygcW"
                     /locus_tag="ACHY1N_004138"
     CDS             complement(12175..12960)
                     /gene="ygcW"
                     /locus_tag="ACHY1N_004138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417254.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4046346.1"
                     /translation="MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGAN
                     IFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNA
                     GICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
                     QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVL
                     DHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR"
     gene            13279..14556
                     /gene="yqcE"
                     /locus_tag="ACHY1N_004139"
     CDS             13279..14556
                     /gene="yqcE"
                     /locus_tag="ACHY1N_004139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter"
                     /protein_id="HFS4046347.1"
                     /translation="MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSN
                     TEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVML
                     CIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFS
                     RFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVL
                     RISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPL
                     GGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYAS
                     RGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWL
                     MGMAALAMVIVFTFLLFQKIRTADSAPAMASSK"
     gene            14583..16061
                     /gene="ygcE"
                     /locus_tag="ACHY1N_004140"
     CDS             14583..16061
                     /gene="ygcE"
                     /locus_tag="ACHY1N_004140"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HFS4046348.1"
                     /translation="MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDAD
                     TAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLIS
                     WQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWTWSED
                     AAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAG
                     LLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSW
                     LRDMLGESLIQDARAQDLSPEDLLNKKASSVPPGCNGLMTVLDWLTNPWEPYKRGIMI
                     GFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFA
                     DVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRY
                     DAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA"
     repeat_region   16700..17094
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=16761..16789
                     /rpt_unit_seq="cggtttatccccgctggcgcggggaactc"
     gene            complement(17434..18105)
                     /gene="queE"
                     /locus_tag="ACHY1N_004141"
     CDS             complement(17434..18105)
                     /gene="queE"
                     /locus_tag="ACHY1N_004141"
                     /EC_number="4.3.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HFS4046349.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     EKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLL
                     PLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKH
                     PVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHK
                     YLNIA"
BASE COUNT         4430 a         4723 c         4528 g         4559 t
ORIGIN      
        1 tgtcttgcct ccctgcaaag aagagactaa cattcgaatt gtttgggttc gaacgtaagc
       61 ctcaggttga tagaaatatc gcctggggct tttgtccatc tggaacctcg cgaatgctta
      121 acgccagaca gcctcaagca cccgacgcca ttctatacct gataattctt ccagcggcgt
      181 tcacgtttaa aatcaggaat actgctcgca aaataaaaac gcccccatca tttctgacag
      241 aggcgtttaa tttatccggc aatatttacc cttcgtgcaa tccacattcc ctttttaagc
      301 caaagaaacg tgtttcttct tccgacatgc caggttccca tttacgggtt gtatgggtat
      361 cgcccaccga taaatatcct tcgtcccata atgggtgata tttcaggcca tgtttttgca
      421 gatactgata tatcgttcgg ttatcccagt cgataatcgg cagcacttta aatacgccac
      481 gctgaattgc cagcaccggt aaattggcgc ggctgccgga ttgttcgcgg cgcaggccag
      541 caaaccacgt ttgcgcattc agttctttca gcgcccggtt catcggttcg actttgttga
      601 tttcattgta cttttcaatg ccttcaacgc cctgttccca cagtttgccg tagcgtgctt
      661 cctgccaggc ggcgctttcg gtagcgcggt acactttcag gttgagcttg agtttgtccg
      721 ttaactcgtc aataaagcgg taggtttccg ggaacagata gccggtgtcg gtgaggatca
      781 ccggaatatc cgggtgaatc tgattcacca gatgcaggct caccgccgcc tgaatgccaa
      841 agctggaaga aagtacatat tcaccgggca gattatccag cgcccaggca acgcggcctt
      901 cagcgtccag tttttccagt tcggcgttag tttctgccag cgccagaatg cgatctacct
      961 tcggcagttc gttcagggcg tttagatcga gtttggacat agattcctca ctgtttgcct
     1021 tgcctgatgc gacgctcacg cgtcttatca ggcctacaag accgggctga tggttaatcc
     1081 cacaaatcgc gcgccggatc gagcaccggg cgaatgatgc ccgcacgcac cgtaaagtcg
     1141 ccgaagcctt cacccgcttc gcgctctttc gcccagcgcc ctatcagttc atcaagcgac
     1201 gccaggattt ccggctcggt gatgttttct ttatacatcc gtgggatacg tgtcccaatg
     1261 cggttgccgc caagatgcag attgtagcga cccggtgctt tacccaccag gcccacttcc
     1321 gccagcatcg cgcgaccaca accgttcggg cagcctgtta cacgcatcac gatatgctca
     1381 tcgctgacac catgtttcgc cattaaatta tcgatgttgt cgataaaaga cggcaggaaa
     1441 cgctctgctt ccgccatcgc cagcgggcaa gtcgggaatg acacgcaggc catcgagttt
     1501 tcacgctgcg gcgtgacggc attcattaaa ccgctctctt tggcgatctt ctcgatcttc
     1561 gctttctcgc tttccggtac accggcgatg atcagattct ggttcgccgt aatgcggaaa
     1621 tcgcctttgt ggatcttcgc gatctccagc aggccggttt tcagcggacg ccccggataa
     1681 tcaaggatgc gaccattttc gataaacagc gtcaggtgcc agttatcatc aatgccctta
     1741 acccagccaa tacgatcgcc tcgtccggtg aactcatatg gacggatcgg ttcaaatttg
     1801 atccccgcgc gacgctccac ttccgcttta aacgtctcaa cccccacgcg ctccagcgtg
     1861 tatttggttt tggcattttt acgatcggtt cggttacccc agtcacgctg agttgtcacg
     1921 acggcttccg ccaccgccag cgtatgctcc agcggcagat agccaaactc gctcgccgtg
     1981 cgggcgtagg ttttcttgtt gccgtgttcg atagaaagcc caccgcccac cagcaggttg
     2041 aagcctacca gcttgccgtt ttcggcgatt gccacgaagt tcatgtcgtt ggcatgcaga
     2101 tcgatatcgt tctgcggcgg gatcactacc gtggttttga acttacgcgg caggtaggtc
     2161 tgaccaagga tcggttcttc atcagtagtg gcgacttttt cctggtcgag ccagatctcc
     2221 gcatacgcgc gggtacgagg caacagatgc tcagaaatct tcttcgccca ctcgtacgct
     2281 tccgcgtgca gctgcgactc gtaagggttc gaggtgcaga gtacgttacg gttcatgtcg
     2341 ttagctgtcg ccagcgcatc aagaccgacc gagtgcagca tctggtgcac cggtttgacg
     2401 ttctttttca gaatgccgtg gaactgaaac gtctggcggt tggtcaggcg aatgctgcca
     2461 tagatggtgt tttcaccggc aaatttgtcg atcgcctgcc actgtttagt ggtaatcacc
     2521 ccacccggca gacgacagcg aagcagcatc gcgtggcgcg gctccagctt ctgttcagca
     2581 cgttcggcgc ggatgtcgcg gtcatcctgc tgatacatgc cgtggaagcg gatcagcagg
     2641 aagttatcgc ccttaaagcc gccggtcaga ccgtcgttta aatcttccgc aatggtgccg
     2701 cgcaggtagt tgctttcaag cttcatgcgc tcggcgtctg tcagttttcc ttcgaccact
     2761 aaaggccctg gatgtttttc gctcattagt agacatctcg ctgataacgg cgctctacgc
     2821 gcagctcact taaaaattca tccgccgctt cggtgtccat gccaccaaat tcggcaatca
     2881 cttccagaag tgcctgctca acgtctttcg ccatgcgatt agcgtcgccg cagacataaa
     2941 tgtgggcacc atcattgatc cagcgccaca gctccgcgcc ctgttcgcgc agtttgtctt
     3001 gtacgtaaac tttttctttt tggtcgcgcg accaggcaag atcgatacgt gtcagcacgc
     3061 catctttgac gtagcgctgc cactccacct ggtacaggaa gtcttccgta aagtgcggat
     3121 taccaaagaa cagccagttt ttacctggcg cttcgtcggc ggcgcgttgc tgcataaagg
     3181 cgcggaacgg cgcaataccg gtgcctgggc caatcataat caccggggtt tccgggttag
     3241 cgggcaggcg aaagttatcg ttatgttcga taaatacgcg gacttcgccc tcttcttcca
     3301 cgcgatccgc gaggaagctg gaggcaccac cggcacgggc tcggccttcc acgtcgtaac
     3361 gcaccacacc aacggtgacg tgtacttcgt tctcgacttc cgcctgcgag gaggcgatgg
     3421 aatacaggcg cggggtcagc gggcgcagca gattaatcag cgcttcggca tccagttgcg
     3481 ccggagagaa acgcaccatg tcgacaatcg gcgtcgtcgc ggcgtaatgc tgtaacttcg
     3541 ctttatcgcc caccagcggc agcagtgttt cactgcgggt aagcgtggcg taattctcaa
     3601 caatgttggc ggtgttgacg gtcagttcga agtgccactg tagcgcttcg ttcagaggca
     3661 acgttttgcc ctcgacggtg acaggttcat cgcctttcag ccacagcagt tcgacaagtt
     3721 ctttcaccag tgccggatcg ttctgatacc agacgcccag cgcgtcaccc ggctggtaac
     3781 gcaggcccga gtcacctaag tcaatttcga tatggcgaac gtctttttca gagttacgtc
     3841 cggtaatttt ctggttaacc gaaaggctcg ccaccagcgg agcgtctttg ctgtacgggc
     3901 tggagtggat ttcatttacc gcgccagtag cgacggattg cgaaggtgcc gcgacaggcg
     3961 cacgcgattt aagcgcatca accacgcggg cgcgccactc gctggcagca gcctggtatt
     4021 caacatcggc atcgacacgg tcgagcaggc gttcaccgcc cagttccgcc agcttgctgt
     4081 caaaatcttt cccggactgg cagaaaaatt cataagagct atcgccgagg ctaaacacgg
     4141 caaatgcggt gttttccagc ttcggcgctt ttttggagaa caggaactta tgcagcgcga
     4201 cggcttcttc cggcggttcc ccttctcctt gcgttgacgt caccacgata agcagttttt
     4261 cgctggcgat ttgtttgaat ttatagtcgc ccgcgttcac cagcttaacg ttcagttttg
     4321 ctgctaataa atcatcgcgt aatgcttcag caacccggcg cgcattgccg gtttgcgagg
     4381 cggagataat agttataccc ggcatttctg cggctggcgc tggcgtcgct gcaagcgcag
     4441 caggctgctg attgagtacg ccccagaaat agccagaaac ccaggcaagc tgggtgggag
     4501 ttaaatcggt cgtggccgcc tgaaggcgtg ccagttgctc cgggttcaac ggaagcaacg
     4561 cggaaggtgg gacctgtgtc gtcatgcgtc gttatgttcc agtaagcaaa gctgtttctg
     4621 cgccctgtca gcgcccataa aacagaagag aaggtaaggt taacggggtg aacggtgtgg
     4681 attaaagacg ggatagcgat aactaataac caaatcgact aacctgtttt agcaatagtc
     4741 tttaacaaca aaatagatta accaacctaa tgaaaaacaa atgaatttag ccaatcatta
     4801 agataaatca gcgattttgc gcaacaaagt cgttttagat aatgcgaaaa aacagccttt
     4861 ccggtactct acggcggttt tatcgtcctg tagagaaatt atgatgtcca ccacgttatt
     4921 taaagatttc accttcgaag ccgctcaccg cttaccacac gtcccggaag ggcataaatg
     4981 tggtcgcctg cacgggcatt cctttatggt gcgactggaa attaccgggg aagtcgatcc
     5041 gcatacgggc tggattatcg atttcgctga actaaaagcg gcgtttaagc caacttatga
     5101 gcgcctcgat caccattatc tcaatgatat tccaggtctg gaaaacccaa ccagcgaagt
     5161 tttagcaaaa tggatttggg atcaggttaa acccgttgtg ccgctgttaa gtgcggtgat
     5221 ggtaaaagaa acctgcaccg ctggttgtat ctatcgcggc gaatgataag agtgtgtcgg
     5281 cggtcaattt cccttaagta acgctatgtt agggtgttgt gttctggata tctggggcat
     5341 gacatggaag acgactgcga cattattatt attggtgccg gtattgcagg caccgcttgc
     5401 gcgttacgct gcgcgcgagc gggtttatcc gttttgttac tggaacgcgc tgaaatcccc
     5461 ggcagcaaaa atctttccgg cgggcggtta tatacccatg cactcgcgga actcctcccg
     5521 caatttcatc tgaccgcgcc tcttgaacga cgcatcactc acgaaagcct ttccctgtta
     5581 acgcccgatg gcgcaacgac gttttccagc ttacagcccg gcggtgaatc ctggagtgta
     5641 ttacgtgcac ggttcgatcc gtggctggtt gccgaagccg aagaagaagg tgtcgaatgc
     5701 atccccggag cgacggtgga tgcactgtat gaagaaaacg gcagggtgtg tggtgtcatt
     5761 tgtggtgacg atattctccg tgcccgttat gtggtgctgg cagaaggtgc caacagcgtc
     5821 ctggctgagc gtcacgggtt agtgactcgt cctgctggtg aagcgatggc gttggggatc
     5881 aaagaagtgc tgtcgctgga accatccgct attgaagaac gttttcatct ggagaataac
     5941 gaaggcgcag cgttgctgtt cagcggcagg atctgtgatg acttacccgg cggcgcattt
     6001 ctttatacta atcaacaaac gctctcgtta gggattgttt gcccgctctc ttcccttacg
     6061 caaagtcgtg ttccggcaag cgagctgctg actcgcttta aagcgcatcc ggcagtgcgc
     6121 ccgcttatca aaaacacgga atcactggag tatggtgcgc atctggtgcc agaaggtggc
     6181 ttgcacagta tgccggtgca atacgccggt aacggctggc tgctggtggg cgatgcgttg
     6241 cgcagttgcg tcaataccgg aatttccgtg cgcggcatgg atatggcgct gactggcgcg
     6301 caggcggcgg cacaaacgct gataagcgcc tgccagcacc gcgagccgca aaatctgttt
     6361 gcgctttatc atcacaacgt agagcgcagc ctgctatggg atgttctaca acgttatcag
     6421 catgttccgg cgcttttgca acgccctggc tggtatcggg cgtggcctgc gttaatgcag
     6481 gatatttccc gcgatttatg ggatcagggt gataaacctg ttccaccgct gcgccagtta
     6541 ttctggcgtc atttacgtcg tcatggcctg tggcatctgg cgggcgatgt tatcaggagt
     6601 ctgcgatgtc tgtagcccat aatctctggc gcgttgctga tgcgccgcac attgttccgg
     6661 ctgactccgt tgagcgtcag atggtacaac ggttgattaa cgcctgtccg gcaggtcttt
     6721 tttcgctcac accggaaggt gacttacgcg ttgattatca cggctgcctg gagtgtggca
     6781 cctgccgttt gctgtgcgac gaatccacac tacaacagtg gcgctatccg ccttccggat
     6841 tcggcatcac ctaccgcttt ggataaataa taaggataat ttatgcccct cttacacctg
     6901 ctccgccaga atccggtgat tgctgccgtt aaagataatg ccagcctgca actggcaatc
     6961 gactctgaat gccagtttat ttccgtgttg tacggcaata tctgcaccat cagtaatatc
     7021 gttaaaaaga ttaagaacgc cgggaaatat gcttttattc atgttgattt gctggaaggc
     7081 gcgtcaaata aagaagtcgt gattcagttt ttgaaactgg tgaccgaggc ggacggcatt
     7141 atcagtacca aagcctcaat gttgaaagcg gcaagagcgg aaggtttttt ctgtattcat
     7201 cgcctgttta ttgttgattc aatttcgttt cacaacattg ataagcaagt tgcgcaatcg
     7261 aatccggatt gtattgagat cctgccaggc tgtatgccca aagtgctggg ctgggtgaca
     7321 gagaaaatcc gccaaccgct gattgccggt gggctggtgt gcgatgaaga agatgcgcgt
     7381 aatgcgatta acgcgggtgt cgtggcgctt tccaccacga ataccggggt ctggacgtta
     7441 gcgaaaaaat tactttgacg ggataatcgt aaccaattga atttggtttg atttgtaggc
     7501 cgcacgccat atccgacatt cagcgcctga tgcgacgctt gacgcgtctt atcaggccta
     7561 caagtcccca ggccagaacc gtaggcagga tcatccggca acacgttatt ggcaatctgc
     7621 gtgaatgttt gtcaccagtg cctccagcac cactttccag tcatcaacca cgccaacatc
     7681 tgcctgtgaa aataccgcag cgctggcgtc atgattaatc gccaccacaa acttgctatt
     7741 gcgtacgccc gccattaacg ctgctgcgcc agaagcgcca acaacaatac acacctcagg
     7801 tgccagcaga tgtccggaaa taccaatcac tttttcagca tcaacgccac cgttcatcac
     7861 tcgcgcccga ctgtagccca cttcggctcc cagcttttct gccagcatag cgatttcctg
     7921 gttatctgcc tctccgccct gccccaccac cagcacccgt ctggcctcag ctaatgggtc
     7981 gcgagtaaca tttttcagat cctctgtgct aaccagccag tcgggaagcg cacccgggac
     8041 aatgttcagt tgttgcattc cagagggcaa cgtggcgttt ttcgctgctc ccgcctgacg
     8101 cgccagggaa aggcatagcg ggcgtttttc tgtttgcagc gtcgccgtta gcgcatttcc
     8161 ccagtgggat ttgcgcacgc ttacggttgg aatatctaac gaagtcacct ggcagatgct
     8221 tgcaccatgt aaacgccagg ccagccgggt cgacagttca tcgccaaacg ttcccggcgg
     8281 aaagagaaca acgtccgcag gcgttcgctg ccactgttcc accaacgcat ccagcacctg
     8341 ttccgccact accggctgag gttcaatctg ccagtgcgcc agggtacaac cgctgaaatc
     8401 ctgcgccgcc agccagcttg ctattgcggc attctcctga tttattgtca caattgcgat
     8461 attcatggct gcatcctttg gcgtaaatag tcctgccata gcttttgagc tttttctgct
     8521 accgtttgcc catcaatcag cgtcgctccg cgtcgttgct ctgctcttgc cagttgcaga
     8581 cactgcatcg ctggcatttc ggcagcaaca gttttacgga taatttctgc tttccccgca
     8641 gccattcgct ggcgcattcc cggtactggc aaggccactt caccgcactg acgcacggca
     8701 atcaccgcag gcaagcgaac ccggcaacaa cgcaacccat gttcagtacg ctgttcgagg
     8761 gtgataaaca gcgcgtcgag agtgaaacgc tccacctggg tgaagcaggg ccagcccagc
     8821 atttccgcca gcaaaaatgg cgtttgccca ttctgccctt cgctgctttg gcagccggta
     8881 attatcagat ccagcggatt ctgatgctgc cattcggcaa tatggcgagc gacaaattcc
     8941 ggcgcaaagc gcagatctgc cgccgtctcc agcaatacag cttcctcaaa cccaagagcc
     9001 atgagatagc gcagccagtg caatgcccgt tcatccccca tgctcaacgc ggttaaagac
     9061 atcggcgtac cgttttttct ctgcgccaac agcagcgcgg cagcggcctg ttcatcagca
     9121 ccgagtaaac ttcgcagtag cgaaatatcc ggtccgcttt taccctgagc cgccgcctgc
     9181 cactcttttt ccgccagcat tccggcatcc ggttcggctt taaacgctaa cagaatgttc
     9241 attcgcacct cctacatttc ccgccgccac cagcgggagg gctttagttt ctggtgccca
     9301 tagccaggtc acaacaaaac caaccaacaa cactgtcgcc aggagcaata aggtgacttg
     9361 cattccccac tgcgccagca cccacggcag caggccagta cttaccgccg cgccaagtcg
     9421 actcatggcg gtggcaaaac cgacgcccag cgagcgaatg tcagtaggaa aactttccgc
     9481 aggcaaaatg cccaccagat tactgactgc cgaaatggtg gtgctgaaga gaacaaaaag
     9541 cagcagcgtt aatgaactgc cggaaggcaa acaggccatg actaccagcg ttgccgccag
     9601 cagcaaaaaa cttcccagca aaaatttgcg atgtgccagc aggtgcgtca gaactaatcc
     9661 caacagcgcg cccacaatta acaacgcatt aagcatcagg ctggcagtca gcgcatcttc
     9721 cagaccaata gtctgggcga tagttggcag ccaggtataa atcacaaacc atgggattac
     9781 gaggcagaca aagaagacgc tgttaaacgc cgtgcgccgc cagtaacgcg aagagaacaa
     9841 ggttttgatg tgtttatggg tcgccgttac cacttcatcg cccagtaaaa catggggacc
     9901 aaaatagcga tgcacgatag cgtgagcttc tgcaaaacgc ccctggcgca gtagccagcg
     9961 tggtgattct ggcgttcccc agcgtaataa cgtaatcaac aacgcgggca gagctgccga
    10021 tgccagtagc cagcgccagg cctccgggtt ttcggaaata aagtgatgtc cggcaatact
    10081 tgccagcaca tagcctacgg tccacaccac gctgaatgcg cccagcaaaa taccgcgatg
    10141 gcggcgcggg gaaaattcag ccagcaaggt gtgacctact gaataatcgc ctcccagact
    10201 aatgccaatc aaaatgcgca gtccaataag atgctctggc gtggtggcaa aaaattgtaa
    10261 aaacgaagca agcgtaatca gcaaaaagct gaaggtgaag attttttgcc gaccaatatg
    10321 gtcggagatc cacccaagaa ccaggctgcc aaggaacaaa ccaaggagcg ccgagccgcc
    10381 gatcattccc gccataaacg gcgtcagttg catggcgggc gtaagctgaa taatggcgta
    10441 accaatgacg ccgagaacat aaccgtcggt caggtgtgcg ccgaaagtga gcgcagcaat
    10501 gcggcagtga aaacggttaa gcggtaaatc atccattcgc accggtgaag tgttcatctt
    10561 taccccttca ttgtccggta ataagaacgg cttctcgcct gagaagccga aaaggcaacg
    10621 ccccgtcatc gcggaacgct gcctgacaca ttatttttca atcggataga tagtacccgt
    10681 attcataatg ccattaggat cgaactgctt tttcagccct tccagcaacg cccacgcgct
    10741 gccgtgttcc agtttgctcc agtgaacgcg atgtttaccg ataccgtggt ggtgcaccat
    10801 cgaaccgccg aggcgaatgg tttcttcaca gatgatcttg ttgagcggat tgtggtactt
    10861 gtcgatttcc tcttccggct tacagtcaac gacgttgtaa tcgtagacga agtacatgtt
    10921 ggtgccgttc tgatagctat gagaggaatg accgcccagc atggtgatgt cgtcggcgtg
    10981 cgggaactca gtacgaatac ggttaataac gctttcgtag atttcgtgga tgcagctcca
    11041 gcagccggac acttcagtgg taaagcccat gttgccggtt ttgaggatct gcacacgttc
    11101 ggcagccact ttatccggtc cccagttcag gttgttaaac caggtttcga tcagcttgct
    11161 gtccacgcgc tggcattgcg ggtagcgggc aacgatttcc gcaatccctt cgcccgtcgc
    11221 cttcgcaatg cgagggttac cttcagccat aaagatcagc acgcattttc cgtctgcaaa
    11281 atgggtgaag tgttgggtgc catcttcagc gtcatacaaa cgagcgatcg acggacgata
    11341 cccttccacc atgacttcac gcaggatgtt gaagccggtt ttcatgtctt ccaggatata
    11401 gccgtagaag aggttgtttt ccggggtgaa tttaaagatt ttcactgtta cttcagtgat
    11461 atagcaaagt gcaccttcgt taccgatgat gatgtggcga atgtccgggc cagccgcgcg
    11521 gcgtggcacg tttttaatgc gtgtgacggt gccatcagcc aatactgctt ccagaccaac
    11581 gaccatatct tcgattgcgc cgtagagtgt ggagaactgc ccgatactgc gggttgctac
    11641 caggccgccc atctgagcca gcggctttga ctgcggagaa tgccccgtgg tgtaaccttt
    11701 ttcacgcaac gcattttcca gcacctccag cggaacgcca cattgcgccg tcgcctgcat
    11761 attctcaata tcaatattaa tgatttgatt catggcggag ccgtcgagca ccaccgagtt
    11821 ttccacaacg gtttccagcc caccttcagt ggcggaagcg ccggtacgcg gcacaccgtt
    11881 aattttgtgc gcattcataa aattcagcac acgggagact tgttctgtgg aaccgagttt
    11941 tacgaccgct gccggaatcg gcaaagtata aataccatga atatccggaa atttacgaaa
    12001 acggtcaata ctgttcttct ttaatactgt ttcatcggta attacgcgat ctgcaccaac
    12061 aatttccttt agctggtcga caatcgctgc gcgagataaa gacatagtaa ttccttcctg
    12121 ataataaaaa tggaataatc attaataaga gaaaacagaa accaccgtta tggattagcg
    12181 cactaaataa ccaccatcga ccactaataa atgcccattg acataatttg aagccggact
    12241 tgcgaggaat acagctgcgc ccattaaatc ctgagtatcg ccccaacggt ttgccggaat
    12301 atgatcaaga acgcgctgat tggtttctgg attactgcgt gtcgccagcg taatatctgt
    12361 tgcataatag ccaggggcga taccatttac ctgaatatta tattgaccta gctcatcaca
    12421 ataagctttg gtgaacccgg caagagcatg tttagtggca gaatatgcag gtgaccattg
    12481 tccacctaag taagagaaca atgaacagat attaataatt ttgccgcttt tctgcgggat
    12541 cataattttt gcagcttcat agcttaactc gaatgcggcg gtcaggttca catcaatcat
    12601 cggatcccag tcggcacgac cgaagtccag caccttattc agcttacaaa taccggcatt
    12661 gtttaccaga atatcaactg taccgaaacg ctcacagcaa gcagcgataa tcttctgcgg
    12721 cgcgccttct gcggtgatat ccacctgcat gaagtccacc tcaacaccct gtttttcaat
    12781 catttccttt gtttcgccgt tatctttgac gaaactagga ataaagatat ttgcgccagc
    12841 tttggccaac gccatggcaa atgcctggcc taaaccgcta ttcccaccgg taacaattgc
    12901 ggttttacct ttcagtgaga aaaaatccat tgagaacgca ttgagagatt cgattgacat
    12961 agttagctcc aatttccgta aggcaaaaaa aaagaaaggt aacttccccc gcgagaggga
    13021 agttaccttt ctcattatct ctggtaactg gagataattt ttagcataac ggcataactg
    13081 ctaatgtgat cgtaatcaca gtgtgatatt cgtattgtca aatagtttta aaaagcagaa
    13141 gcgtgattac tctcacacaa cacctctgct ttccatgtta tttcttattg caattactag
    13201 agacctgaga aaagtaatcc acctgaaagg gcggcttact tttctctttt ttttgtctat
    13261 tacaaatggg aatacgatat gcaacacaac tcatatcgcc gttggataac cctcgcgata
    13321 attagtttta gcggcggcgt tagtttcgac ctggcttatt tacgttatat ttatcaaatt
    13381 cccatggcga aatttatggg attcagcaat accgagatag gtttaataat gagtaccttt
    13441 ggtattgcgg ctattattct ttatgccccc agcggcgtta ttgccgataa attttcacac
    13501 cgcaaaatga ttacttccgc gatgatcatt accggattac tgggtctgtt aatggcaacg
    13561 tatccaccgc tgtgggtaat gctctgtatt caggtcgcct ttgcgataac gacgatttta
    13621 atgctgtggt cggtgtcgat taaagccgcc tcgttgctgg gcgatcatag tgagcaaggg
    13681 aaaattatgg gctggatgga agggctgcgc ggcgtcggtg taatgtcgct ggcggtgttt
    13741 accatgtggg tcttttctcg ctttgcaccg gatgacagcg ccagcctgaa aacagtcatt
    13801 atcatctaca gtgtggttta catcttgttg gggattctgt gctggttttt tgttagcgat
    13861 aacaacaacc tgcgcagtgc caataacgaa gaaaaacagt cattccagct tagcgacatc
    13921 cttgccgttt tgcgtatcag caccacctgg tattgcagca tggtgatttt tggtgtcttc
    13981 acaatctacg ccattctgag ttactccacc aactatctga ccgaaatgta cggcatgtcg
    14041 ctggtggcag cgagctacat ggggattgtg atcaacaaaa tcttccgcgc gctgtgcggc
    14101 ccacttggcg gcattatcac cacctacagt aaagtgaaat cccctacccg cgtgatccaa
    14161 atcctttccg tactcggcct gctggcgtta actgccctgc tcgtcacgaa ctctaacccg
    14221 caatcggtcg cgatggggat tggcctgatt ttactgctgg gattcacctg ttacgcctca
    14281 cgcgggctgt actgggcctg ccctggcgaa gcgagaacac cgtcttacat tatgggcacc
    14341 acggtaggta tttgttcggt gattggattc ctgccggatg tcttcgttta cccgattatc
    14401 ggccactggc aagacaccct gcccgcagca gaagcctacc gcaatatgtg gctgatggga
    14461 atggcggcgc ttgccatggt gattgtcttt acctttttgc tgttccaaaa aattcgtact
    14521 gctgatagcg cccccgcaat ggctagcagc aagtaagcca ggaaaattac aggagaaaaa
    14581 tcatgtcgaa aaaatacatc atagggattg atggcggaag tcagagcaca aaagtggtga
    14641 tgtacgatct ggaaggtaac gtggtttgcg aaggcaaagg cttattacag ccgatgcaca
    14701 cgccagatgc cgatactgca gaacatcctg acgacgattt atgggcatca ttatgttttg
    14761 ccggtcacga tttgatgagt cagtttgctg ggaataaaga agatattgtc ggtattggtc
    14821 tgggatccat ccgttgctgt cgtgcgttat tgaaagccga tggcacgcct gctgcgccgt
    14881 tgattagctg gcaggatgca cgcgttacac gcccttacga acacactaat cctgacgtgg
    14941 catatgtcac ctctttttcg ggttatctga cgcatcgctt aaccggcgag tttaaagaca
    15001 atatcgccaa ctattttggt cagtggccgg tggattataa gagctggaca tggagcgaag
    15061 atgctgcggt aatggataag tttaatatcc cccgtcatat gctgtttgat gtgcaaatgc
    15121 ctggcaccgt cctcggacat atcacaccac aagccgcact ggcgacacat ttcccggcag
    15181 gactgccggt tgtttgtacc accagtgata aaccggtaga agctctgggg gccggattac
    15241 tggatgatga aactgcggta atttctcttg gcacttacat cgcattgatg atgaacggca
    15301 aagcactgcc gaaagatccg gtggcgtact ggccgattat gtcttctatt ccgcaaacat
    15361 tgctgtatga aggttacggt attcgcaaag gtatgtggac ggtgagctgg ctgcgtgaca
    15421 tgttaggcga gtcgttaatt caggatgcca gggcgcagga tctttcaccg gaagatttac
    15481 tcaacaagaa agcctctagt gtgccacctg gctgtaatgg gctgatgacg gtgctggact
    15541 ggctgaccaa tccgtgggaa ccgtacaaac gcgggattat gatcggcttt gattccagca
    15601 tggattacgc atggatatat cgttcgatat tggaaagcgt ggcgctaacg ctgaagaaca
    15661 attacgacaa tatgtgtaat gaaatgaatc actttgcgaa gcatgtgatc attactggcg
    15721 gcggttcgaa cagcgatctg tttatgcaaa tttttgccga cgtgttcaac cttccggcac
    15781 gccgtaacgc cattaacggt tgtgcaagtc tgggagcagc gattaataca gcggtaggtc
    15841 tggggctata cccggattac gcaacggctg ttgataagat ggttcgcgtg aaagatatct
    15901 ttataccgat tgagagcaat gccaaacgct acgacgcgat gaataaaggc attttcaaag
    15961 acctaaccaa acatactgat gtgatcctga aaaaatcgta tgaagtgatg catggggaat
    16021 tggggaatgt ggattcgatc cagagctggt cgaatgcgta agtgaggaag gccgggcggg
    16081 aaactgcccg gcctgaacat acctgaatgg ttatccccgc tgacgcgggg aacataagtt
    16141 cgacaactta aaaaatgata acaagtccgg tttatccccg ctgatgcagg gaacataata
    16201 aaaactttaa ctagttcggt ttatccctgt ttttacaagg aatattaact acactcgatg
    16261 tctttagaat aaaagacaat acgaatcgca ctttatcaat tttcacttaa agtatgaact
    16321 ggatatcttt attcataaga actattcatc aacagcgtat agaggcggtt atgtaaaacc
    16381 actcattagc ctcaaaacaa agacaaactt ccagatttat tacttaacca atgaataaca
    16441 agcttaaaaa acatactgtt attctaaaga aaaaattaac aggcattaat tcaatattaa
    16501 aaaaataata gattaaaatt tcttaacgat ttaagaatca tacaaataac actttgatta
    16561 aatttaattt tttgtatcga taattgtgaa cctctctggc atggagaact attttgaaca
    16621 tgaggtgtta cgtggatatg ttgcttatta caagtactgc taatataaaa acttgagaaa
    16681 gagataacgg gttatatggt ggtttatccc cgctggcgcg gggaactcgc ctgacattgc
    16741 agacgttaca aattgagagg cggtttatcc ccgctggcgc ggggaactca agacgacgtg
    16801 atccgcaaag tcgaaggcac gcggtttatc cccgctggcg cggggaactc tgtttttctg
    16861 ccggtttaac acggtgcgat aacggtttat ccccgctggc gcggggaact ctgtttctgt
    16921 cccaactgaa cagcgccgat agtcggttta tccccgctgg cgcggggaac tcgaatgatc
    16981 ccaaatttgg gttacagaac cagtcggttt atccccgctg gcgcggggaa ctcggactta
    17041 aagatcgcat cacagtactg gagggcggtt tatccccgct ggcgcgggga actctgtaaa
    17101 cataacctat tattaattaa tgatttttta agccagtcac aatctaccaa ctttatagta
    17161 tcacacaaac aacacatcca ttatgttaaa gagcacttaa tccattgatt aaaaaggtaa
    17221 atatttaaaa taactctata caaactaaaa tctaccaaac tttaccgcaa taattttcac
    17281 tccagcgaaa aattaatgcc acagaatttg tagagaatgc taatgattag ccctggatgg
    17341 gtaaaatgga ggagttttca gaggcgacaa acaatataaa tgagtagaag tctttacagg
    17401 ttccacccat ttataacgct tataaatgtt taatcaggca atatttagat atttatgtgt
    17461 ttgcatcgac aaacgccaat tacgcgcaat gcaggtttca atgcacaaac gtgtggcatc
    17521 atccttttgg ctaatcggct gcagtgcaat gactcgcggt ttatcatcgg tcagcgttgc
    17581 cagtagttca tccagtgctt caatatcacg tacgcgcccc actggatgct tgatttcgtt
    17641 ggctcgctcc agtgcctgtg acaacacgtc atagccgccg cgcatgttca gctttggcga
    17701 tacggtaacc caggtattcg gtgtgcagcg tacttcatga gttccactgg tttcgatctg
    17761 gcagctaaaa ccgttctttt cgagcaggtc agtcagtggc agcaaatcat gaatgcaagg
    17821 ctcaccaccc gtaatcacca catgccgcgc ggtatatccc tgccgaccaa tgacagccag
    17881 caaatcttca ctgctcgccg ccccccactt atcactctct ttggtcttcg ccagaatgct
    17941 gaaaagggag acttcccgat cctcaagctt ttcccaggtg tgtttggtgt cgcaccaggc
    18001 acagccaacc gggcatccct gtaaacgaat aaaaatggcg gggacgccgg taaagtaacc
    18061 ctcaccttgc agggtctgga acatctcgtt aatcgggtac tgcatagcat tctctgtgaa
    18121 gtggataatt gttaattatt gcagatcctg ccgcaacaat catgtcttat taacattctg
    18181 ttacaggcag atttaaagaa aaatgcgaaa catatcgtta ataattaaag ggagtaacgt
//
LOCUS       DAZUDJ010000085        17315 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.085, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000085 DAZUDJ010000000
VERSION     DAZUDJ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17315
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.085"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1089
                     /locus_tag="ACHY1N_004142"
     CDS             <1..1089
                     /locus_tag="ACHY1N_004142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046930 - pore complex [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HFS4046350.1"
                     /translation="PVQIEISPGDREGWSVVTLTALPEWPVTGSVGIDNSGQKNTGTG
                     QLNGVLSFNNPLGLADNWFVSGGRSSDFSVSHDARNFAAGVSLPYGYTLVDYTYSWSD
                     YLSTIDNRGWRWRSTGDLQTHRLGLSHVLFRNGDMKTALTGGLQHRIIHNYLDDVLLQ
                     GSSRKLTSFSVGLNHTHKFLGGVGTLNPVFTRGMPWFGAESDHGKRGDLPVNQFRKWS
                     VSASFQRPVTDRVWWLTSAYAQWSPDRLHGVEQLSLGGESSVRGFKEQYISGNNGGYL
                     RNELSWSLFSLPYVGTVRAVAALDGGWLHSDRDDPYSSGTLWGGAAGLSTTSDYVSGS
                     FTAGLPLVYPDWLAPDHLTVYWRVAVAF"
     gene            1102..10731
                     /gene="cdiA"
                     /locus_tag="ACHY1N_004143"
     CDS             1102..10731
                     /gene="cdiA"
                     /locus_tag="ACHY1N_004143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="contact-dependent inhibition effector tRNA
                     nuclease"
                     /protein_id="HFS4046351.1"
                     /translation="MNQPPVHFTYRLLSYLVSAIIAGQPLLPAVGAVITPQNGAGMDK
                     AANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLK
                     AGGEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPHATLTT
                     GRPVMNADGSLQALEVTEGSITINGAGLDGTRSDAVSIIARATEVNAALHAKDLTVTA
                     GANRITADGRVSALKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYARE
                     GDIILNSAGKLVLKNSLAGGNTTVTGTDVSLSGDNKAGGNLSVTGTTGLTLNQSRLVT
                     DKNLVLSSSGQIVQNGGELTAGQNAMLSAQHLNQTSGTVNAAENVTLTTTDDTTLKGR
                     SIAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTSTGSIK
                     SGSTLDISARNATLSGDAGAKDSARVTVSGTLENRGRLVSDDVLTLSATQINNSGTLS
                     GAKELVASADTLTTTEKSVTHSDGNLMLNSASSTLAGETSAGSTVSVKGNSLKTTATA
                     QTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSGKSSAPSLSLSAPELTSSGVL
                     VGSALNTQSQTLTNSGLLQGKASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLI
                     TGDNGLTLNTASLSNPGKIIADTLNVRATTLDGDGLLQGAGALALAGDTLSQGRNGRW
                     LTAGDLSLRGKTLHTAGTTQGQNLTVQADNWANSGSVLATGNLTASATGQLTSTGDIM
                     SQGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNRGTVQGDHVTIRQNSVTNSGTFTGI
                     AALTLAARMVSPQPALMNNGGSLLTSGDLTITAGSITSSGHWQGKRVLITADSLANSG
                     AIQAADSLTARLTGELVSAAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSLTSA
                     GDITGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVTNDGQLQGNATTITAGQLTN
                     GGHLQGETLTLTASGGVNNRSGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNATDRL
                     QNDGKILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSADVKGTTL
                     NNTGTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNLLLDAQDF
                     SGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVLGAGEA
                     FTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMN
                     VAGTLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDSSGTANSEIINRSGNI
                     ETTRGDITMNTAHLLNSWDAISASHEVIPGSSHGVISPVPENNRWWGVVRHDGVEYLA
                     VYWGEGATVPDEYRIRTGDTETVTVSASGHAARISGGADMHIRAGRLDNEASFILAGG
                     SMTLSGDTLNNQGWQEGTTGKETVWRLASGSLPKAWFTEPWYKVYRQVSTDATEASGT
                     SPAGQYRAVISAASDVSASFATDTGNTTVMPRAGGAGNTITVPSLNSLTPPTVSQGVS
                     GEALLNESGTGITGPVWNDALPDTLKDIPGALSLSGASVSSYPLPSGNNGYFVPSTDP
                     DSPYLITVNPKLDGLGKVDSSLFAGLYDLLRMQPGQAPRETDPAYTDEKQFLGSSYIL
                     DRLGLKPEKDYRFLGDAAFDTRYVSNVILNQTGSRYINGTGSDLAQMKYLMDSAAAQQ
                     KALGLTFGVSLTAGQVAQLTRSILWWESVTINGQTVMVPKLYLSPEDITLHNGSVISG
                     NNVQLAGGNITNSGGSINAQNDLLLDSTGSIDNLNAGLINAGGALNLKAIGDIGNISS
                     VISGKTVSLESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAVRATDSLFMGAAGD
                     ISITGAAVSAGDSVLLSAGNDLNMNAIQAGERRRYGGSGWYETHAVAPTVTAGNSLML
                     SAGRDVNSQAAGIMAENSMDIRAGRDVNMAAESTGTGDHDSTFSMKTVHDSVRQQGTD
                     MTSGGDITVTAGRDITSVATAVTAKGDIRVNAGHDIVLGTATESDYHYSESGETRNRL
                     LSHQTTRTITEDSVTREKGSLLSGNRVTVDAGDNLTVEGSDVVADRDVSLAAGNHVDV
                     LAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGTTQSQSASTIGSTAG
                     NVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSG
                     TVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQAAAMATATGDPNATGVS
                     LSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIAGSQLKAGGN
                     TSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFASVNAAKGSEK
                     GNGTEWTETTIDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDLLISGQQDTSKYDS
                     KQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGMFAGDGGFDITVGRHTQ
                     LDGAVIASTATPDKNHLDTGTLGFSDLHNEADYKVSHSGISLSGGGSFGDKFQGNMPG
                     GMISAGGHSGHAEGTTQAAVADGTITIRDRDNQKQNLANLSRDPAHANDSISPIFDKE
                     KEQRRLQTVGLISDIGSQVADIARTQGELNALKAAKEATGETLPANATEKQRQEYLAK
                     LRDTQAYRNEMAKYGTGSEIQRGIQAATAALQGLVGGNLAGALAGASAPELAHLLKST
                     EKYPAVNAIAHAILGGAAAAMQGNNVAAGAAGAATGELAARAIAGMLYPGVKQSDLSE
                     EQKQTISTLATVSAGLAGGLTGNSTASAAVGAQSGKNAVENNYLSKAQKAQKADELAK
                     CQTAACKAQTEAKWTAIDLGQDGSFAAGMIAGVPAGLYDAVDSIVKAGSNPTETLEAM
                     KALFNSGDILGSLSDAVKQSYIDRIDRMEAEYQKAGTSGSFNAGVEGGKLITDIAGLL
                     AGGVGVVKGGAVLTEKVVAKVVGKSESAAAKVGTDIVKTGTVFDSIKATQPAIPGTSI
                     PKSFELHVNGQTVWVNPNATKHMGEYLTRNGLSHSTAEGSQAMLTSLQSAVKDAFSQG
                     LKFNEKMQVGRWELVFSQRSSDPYPVLKHALYK"
     gene            10731..11270
                     /locus_tag="ACHY1N_004144"
     CDS             10731..11270
                     /locus_tag="ACHY1N_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046352.1"
                     /translation="MKLTVDSVINEPRSVAITIDGYIPVDIKIIDSKKLPPLYWRGGD
                     GKKNLLELAVLPENGFLSSITLVMIASDSIHKTDSLSVSLPSSECGVPVVNTKLWSHS
                     ESDDFSRRFVDDFSLDIEVIISSESMLLTIGENKKVTSWIKCSDNFYLGIDAGRNVVH
                     LYLDKLTPSEVESFFEAVG"
     gene            11557..11703
                     /locus_tag="ACHY1N_004145"
     CDS             11557..11703
                     /locus_tag="ACHY1N_004145"
                     /inference="COORDINATES: protein motif:HMM:NF016702.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemagglutinin"
                     /protein_id="HFS4046353.1"
                     /translation="MLVTIASGIAGGLAGNSTASAGTGPWQVRTRLRITTSAMTRRML
                     LTEK"
     gene            11700..12557
                     /locus_tag="ACHY1N_004146"
     CDS             11700..12557
                     /locus_tag="ACHY1N_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001310368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046354.1"
                     /translation="MTACRKAGGDCGDIQNKYAVLSAENRQKLHIDVAADPLTALSGE
                     DKWNIEGGLSAAGRPGWLYGSLTNQEVKDYVAEGNSYDLNYLNSNTSKGDRALAFFGE
                     PENYWGTVAGAGSLLTSSATLTEKFISAGLSYGANGAVQIGTGNIGDKFDYLSFMMSG
                     LTGVGTAGKGYYANQLLGAGSAYMSSQIEGQDSTSSVMGSMAGTGLGYNIGASITNKL
                     EAQYIKNQLGMDASKYSLQYSEKSIGYGMYQGGQMSSIPGTFGGFVGSFVSEGASSAT
                     QKEVDGDKK"
     gene            12970..13413
                     /locus_tag="ACHY1N_004147"
     CDS             12970..13413
                     /locus_tag="ACHY1N_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001449592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HFS4046355.1"
                     /translation="MWALGAGANAGIGSMVDSSVDPENAIIAGWVNVITMGQGWKETV
                     GWNAAGGAFGNWLDGKDPLSGAAMSGGTSAIGYGVGKVVQGPLEKVINPNWKNWEWLN
                     VGMGISKPLPLNPTPGIAGNIGSSIGTEGSGAIIQEQLKNQQEKK"
     gene            13794..14576
                     /locus_tag="ACHY1N_004148"
     CDS             13794..14576
                     /locus_tag="ACHY1N_004148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001310369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFS4046356.1"
                     /translation="MEDLSLKQQQEMIAVCATNPAACKEKYGDIPAKGMLVREAIDRV
                     LGADVPSAMKNDMSSLLAQQIEAEGVVTSTEFASQIQNCYGIDKQQAEILAVAAPGAV
                     TGGMRKSGTSTASKNIVVVDSGKKGAWNQAMNKPEPNTVYKVDGNKTFQTDALGRTSS
                     AEGILVASKSDRNTYQQCKAGKCGSSGDEGGHLIASIFNGPGEKLNLVPMDGNLNKGV
                     WKQMENTWANALKDGKQVNVKIEPVYTGENKRPDSFSVTILY"
     gene            14628..15005
                     /locus_tag="ACHY1N_004149"
     CDS             14628..15005
                     /locus_tag="ACHY1N_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046357.1"
                     /translation="MNELDDLHNKIGQLLVDAGPANAMKIIARAKLSLDGESCEYEYD
                     YLDQEGDEDWFVPDKLASHDLRLLLVKMRDFYIQNNMTNGKPAWIGCEIIVDIPEEKI
                     SINFQYDDLTVIPAPAPGSPQCP"
     gene            15188..15637
                     /locus_tag="ACHY1N_004150"
     CDS             15188..15637
                     /locus_tag="ACHY1N_004150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HFS4046358.1"
                     /translation="MLKIGVEDVDGELLKGGGGIANGRPSHRQSEKDVGKDLGAGWRE
                     QVSYKDGKEVPYGTKGSTRPDWCNGNTCGIEVKNYNIATNINGLINNVSKQAIHRAEN
                     LPAGMQQRIIIDVRGQIVTPNQERTIIKGIVERSNGVIAPTSIRFKR"
     gene            15647..16060
                     /locus_tag="ACHY1N_004151"
     CDS             15647..16060
                     /locus_tag="ACHY1N_004151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046359.1"
                     /translation="MKRVGFCGGSSFFELGSASDMLNFFSYLNKLSRTERDRYLLERI
                     YFKYIKFDEIDESCALLNELKNLCSEDFIHKFSKYFESIKWCSESAKEFYEDWNVYQE
                     IKIIITEMPYCISEMERPKEEYDALTLSDVPFWLR"
     gene            16130..16984
                     /locus_tag="ACHY1N_004152"
     CDS             16130..16984
                     /locus_tag="ACHY1N_004152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VENN motif pre-toxin domain-containing protein"
                     /protein_id="HFS4046360.1"
                     /translation="MRTEKQVVSTLATVAAGLAGGLVGDSGASAVAGAQSGKTTVENN
                     MLNVIATETAANTAAAIACATGNASKDTGNDNSWDIGGGCEGSREQCAVRDPSRDGTR
                     GPGHVLNGDNTDENKQPNLGKDVASATDKEKAELGGAGAGTPGGWEPQDEENARNNES
                     IEQRNEKTSSENVPNSSEKLPWDSWQNYRKVTVDGRQYAQIGHRLYSQHAVDRMQPSG
                     LGSPAGTVGPGRNITPNMVESVIKEGTPQNSVVNGVTRTTYWSGDVGVVTENNSNIIV
                     TILRRSGQ"
     gene            16981..17244
                     /locus_tag="ACHY1N_004153"
     CDS             16981..17244
                     /locus_tag="ACHY1N_004153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046361.1"
                     /translation="MSWIYPEVIERLQHSCKNFLEGKITVQSIQSEIYAAESQIVAVE
                     EKWLHTMLFNAENEIELLLYTVEEEQLVSSVIPIVNNILSKIK"
BASE COUNT         4621 a         3899 c         4932 g         3863 t
ORIGIN      
        1 ccggtacaga ttgaaatatc gcccggtgac cgtgagggat ggtcggtggt gacactgacg
       61 gcattgccgg aatggcccgt cacagggagc gtgggtatcg acaacagcgg gcagaagaat
      121 accggtacgg ggcagttaaa tggtgtcctt tcctttaata atccgctggg gctggctgac
      181 aactggtttg tcagcggggg acggagcagt gacttttcgg tgtcacatga tgcgaggaat
      241 tttgccgccg gtgtcagtct gccgtatggc tataccctgg tggattatac gtattcatgg
      301 agtgactacc tcagcaccat tgataaccgg ggctggcggt ggcgttccac gggagacctg
      361 cagactcacc ggctgggact gtcgcatgtc ctgttccgta acggggacat gaagacagca
      421 ctgaccggag gtctgcagca ccgcattatt cacaattatc tggatgatgt tctgcttcag
      481 ggcagcagcc gtaaactcac ttcattttct gtcgggctga atcacacaca caagtttctg
      541 gggggtgtcg gaacactgaa tccggtattc acacggggga tgccctggtt cggcgcagaa
      601 agcgaccacg ggaaaagggg agacctgccc gtaaatcagt tccggaaatg gtcggtgagt
      661 gccagttttc agcgccccgt cacggacagg gtgtggtggc tgaccagcgc ttatgcccag
      721 tggtcaccgg accgtcttca tggtgtggaa caactgagcc tcgggggtga gagttcagtg
      781 cgtggcttta aggagcagta tatctccggt aataacggcg gttatctgcg aaatgagctg
      841 tcctggtctc tgttctccct gccatatgtg ggaactgtcc gtgcagtggc tgcactggac
      901 ggcggctggc tgcactctga cagagatgac ccgtactcgt ccggcacgct gtggggtggt
      961 gctgccgggc tcagcaccac cagtgactat gtttccggtt cgttcactgc cgggctgcct
     1021 ctggtttacc cggactggct tgcccctgac catctcacgg tttactggcg cgttgccgtc
     1081 gcgttttaag ggattattac catgaatcag cctcccgttc acttcactta ccgcctgctg
     1141 agttacctgg tcagtgcgat tatcgccggg cagccgttgt taccggctgt gggggccgtc
     1201 atcaccccac aaaacggggc cggaatggat aaagcggcaa atggtgtgcc ggtcgtgaac
     1261 attgccacgc cgaacggggc cgggatttcg cataaccggt ttacggatta caacgtcggg
     1321 aaggaagggc tgattctcaa taatgccacc ggtaagctta atccgacgca gcttggtgga
     1381 ctgatacaga ataacccgaa cctgaaagcg ggcggggaag cgaagggtat catcaacgaa
     1441 gtgaccggcg gtaaccgttc actgctgcag ggctatacgg aagtggccgg caaagcggcg
     1501 aatgtgatgg ttgccaaccc gtatggtatc acctgtgacg gctgtggttt tatcaacacg
     1561 ccgcacgcga cgctcaccac gggcagacct gtgatgaatg ccgacggcag cctgcaggcg
     1621 ctggaggtga ctgaaggcag tatcaccatc aatggcgcgg gcctggacgg cacccggagc
     1681 gatgccgtat ccattattgc ccgtgcaacg gaagtgaatg ccgcgcttca tgcgaaggat
     1741 ttaactgtca ctgcaggcgc taaccggata actgcagatg gtcgtgtcag tgcactgaag
     1801 ggcgaaggtg atgtgccgaa agttgccgtt gataccggcg cgctcggtgg aatgtacgcc
     1861 aggcgtattc atctgacctc cactgaaagt ggtgtcgggg ttaatcttgg taacctttat
     1921 gcccgcgagg gcgatatcat actgaacagt gccgggaaac tggtcctgaa gaacagcctt
     1981 gccggcggca ataccaccgt aaccggaacg gatgtctcac tttcagggga taataaagcc
     2041 ggaggaaatc tcagcgttac cgggacaacg ggactgacac tgaatcagtc ccgtctggtg
     2101 acggataaaa atctggtgct gtcttcatcc gggcagattg tacagaacgg tggtgaactg
     2161 actgccggac agaacgccat gctcagtgca cagcacctga accagacttc cgggaccgtg
     2221 aatgcagctg aaaatgtcac ccttaccacc accgatgata ccacactgaa aggccgcagc
     2281 attgccggga aaacactcac tgtcagttcc ggcagcctga acaacggcgg gacactggtt
     2341 gccgggcgcg atgccacggt gaaaaccggg acattcagta ataccggtac cgtccagggg
     2401 aatggcctga aagtcaccgc cactgacctg accagcaccg gcagtattaa aagtggcagc
     2461 acactcgata tcagcgcccg caatgccaca ctgtccggtg atgccggtgc aaaagacagt
     2521 gcccgcgtta ccgtcagcgg tacacttgaa aaccgcggca gactcgtcag cgatgacgtg
     2581 ctgacgctca gtgccacgca gataaacaac agcggtaccc tctccggggc aaaggaactt
     2641 gtggcttctg cagacacact gaccaccaca gaaaaatcag tcacgcacag tgacggtaac
     2701 ctcatgctga acagcgcgtc ttccacgctg gcgggtgaaa ccagtgcggg cagcacggtg
     2761 tctgtaaaag gcaacagtct gaagaccacg gccactgcgc agacgcaggg caacagtgtc
     2821 agcgtggatg tgcagaacgc acagcttgac ggaacacagg ctgccagaga catcctcacc
     2881 ctgaacgcca gtgaaaagct cacccacagc gggaaaagca gtgccccgtc gctcagcctc
     2941 agtgcgccgg aactgaccag cagcggcgta cttgttggtt ccgccctgaa tacacagtca
     3001 cagaccctga ccaacagcgg tctgttgcag gggaaggcct cactcaccgt taacacacag
     3061 aggcttgata atcagcagaa cggcacgctg tacagtgctg cagacctgac gctggatata
     3121 ccggacatcc gcaacagcgg gcttatcacc ggtgataatg gtttaacgtt aaacactgcc
     3181 tccctcagca atccgggaaa aatcatcgct gacacgctga acgtcagggc gaccacgctg
     3241 gatggtgatg gtctgttgca gggcgccggt gcactggcgc ttgcaggcga caccctctca
     3301 cagggccgta acggacgctg gctgacggcg ggcgacctct ccctccgggg taaaacactg
     3361 cataccgcag ggaccacgca gggacagaat ctcaccgtgc aggcggacaa ctgggcgaac
     3421 agtggctccg tgctggcaac cggtaacctt actgcttcgg caaccggtca gttgaccagt
     3481 accggcgata tcatgagcca gggtgacacc acgctgaacg cagccaccac ggacaaccgg
     3541 ggcagtctgc tttcggccgg cacgctctct cttgatggaa attcactgga taaccgcggc
     3601 actgtccagg gtgaccatgt cacgattcgc cagaacagtg tcaccaacag tggcacgttc
     3661 accgggatcg ccgcgctgac gcttgccgcc cgtatggtat cccctcaacc tgcgctgatg
     3721 aataacggag gttcactgct gaccagcggc gatctgacaa tcaccgcagg cagtattacc
     3781 agttccggac actggcaggg caaacgggtg ctgatcaccg cagacagtct ggcaaacagc
     3841 ggggcgatcc aggcggctga cagcctgact gcacgtctga cgggtgagct tgtcagcgcc
     3901 gcgggcagca aagtcacctc gaacggtgaa atggcgctca gtgcactgaa tttaagcaac
     3961 agcggacaat ggattgcaaa aaatctgact ctgaaagcga actcactgac cagtgcgggt
     4021 gacatcaccg gtgtggatgc tctcacgctc acggtgaatc agacgctgaa caatcacgcg
     4081 agcggaaaac tgctcagtgc aggtgtgctg acgctgaagg cagacagtgt cacaaacgac
     4141 gggcaattac agggaaatgc caccaccatc acggcaggac aactcacaaa cggcgggcat
     4201 ctgcagggcg aaacgctgac gctgacagcc tccggtggcg tgaacaaccg ttccggtggt
     4261 gttctgatga gccggaatgc actgaatgtc agtactgcga ccctgagtaa ccagggcacg
     4321 atacagggcg gtggcggggt ttccctgaac gccactgacc gtctgcagaa cgacggcaaa
     4381 atcctctccg gcagtaacct cacgctgacg gcgcaggtgc tggcgaacac cggcagcgga
     4441 ctggtacagg ctgccaccct gctgctggat gtggtgaata ctgtcaacgg cggacgcgta
     4501 cttgccaccg gcagtgccga cgttaaagga accacgctga ataataccgg tacgcttcag
     4561 ggtgcggacc tgctggtgaa ttaccacaca ttcagcaaca gcggtaccct gctgggaacc
     4621 tccgggcttg gcgtcaaggg cagttcactg ctgcaaaatg gtacagggcg gctgtacagt
     4681 gcaggcaacc tgctgcttga cgctcaggac ttcagtggtc aggggcaggt ggtggccact
     4741 ggtgatgtca cactgaaact gattgctgcc ctcacgaatc atggtaccct ggccgcaggg
     4801 aaaacccttt ccgtcacgtc gcaaaatgcc atcaccaacg gcggtgtgat gcagggtgat
     4861 gccatggtgc tcggtgccgg agaggcattc accaacaatg gaatgctgac tgccggtaaa
     4921 ggcaacagtg ttttcagcgc acagcgtctt ttccttaacg caccgggttc acttcaggcc
     4981 ggtggcgatg tgagtctgaa cagccggagt gatatcacca tcagtggttt taccggcacg
     5041 gcaggcagtc tgacaatgaa tgtggccggt accctgctga acagtgcgct gatttatgcg
     5101 gggaataacc tgaagctgtt tacagaccgt ctgcataacc agcatggtga tatcctggcc
     5161 ggcaacagtc tgtgggtaca gaaggacagc agcggtacgg caaacagcga aatcattaac
     5221 cgttccggta atattgaaac cacacgtggc gatatcacca tgaatacggc gcatctgctg
     5281 aattcctggg atgccatttc ggccagccat gaggtcattc ctggaagcag tcacggggtg
     5341 atttcaccgg ttccggaaaa taaccggtgg tggggtgttg tccggcatga tggtgtggaa
     5401 tatctggcag tgtactgggg ggagggtgcc acggtacctg atgaataccg tatccgtacg
     5461 ggagatacgg aaacggtgac agtcagtgcc tccggccatg ctgccaggat atccggcggc
     5521 gctgatatgc atatccgtgc aggacgactg gataatgagg catcgtttat tctcgccggt
     5581 ggcagtatga ccctgagtgg cgacacactg aacaatcagg gctggcagga gggaaccacc
     5641 ggaaaggaaa cggtctggcg gcttgcctcc ggctcactcc ccaaagcgtg gtttactgag
     5701 ccatggtata aggtctatcg ccaggtctcg acggatgcga cagaagccag tggcacctct
     5761 ccggcaggtc agtaccgtgc ggttatcagc gctgccagtg atgtgtctgc cagctttgcc
     5821 actgacaccg gtaataccac tgtcatgccc cgggcaggtg gtgcaggtaa cacgataacg
     5881 gtgccttcgc tgaactccct gacaccaccg acggtcagtc agggggtgag cggtgaagcc
     5941 ctgctgaatg aaagcggtac cgggataacc ggccctgtat ggaatgacgc gctgccggat
     6001 acgctgaagg atatcccggg tgcgctgtcg ctgtccgggg caagtgtaag cagctatccc
     6061 ctgccatccg gtaacaatgg ttattttgtc ccgtccacgg acccggacag tccgtatctg
     6121 attacggtga acccgaaact ggatggtctc ggaaaggtgg acagcagtct gtttgccgga
     6181 ctgtatgacc tgctcaggat gcaacccgga caggcaccac gagaaacaga cccggcatat
     6241 accgatgaaa aacagtttct gggctcgtcg tacattcttg accgtcttgg cctgaaaccg
     6301 gaaaaagatt accgctttct gggggatgcg gcttttgata cccggtatgt cagtaacgtc
     6361 atactgaacc agacgggctc acgttatatc aacggcacag gctctgacct ggcgcagatg
     6421 aaatacctga tggacagcgc ggccgcacaa cagaaagcgc tcggactgac ctttggtgtg
     6481 tcgctgaccg ccgggcaggt tgcacaactg accagaagca tactgtggtg ggagtccgtc
     6541 accatcaacg gacagaccgt catggttccg aaactgtatc tgtctccgga agatatcacc
     6601 ctgcataacg gcagcgttat cagcgggaac aacgtgcagc ttgcgggtgg caatatcacc
     6661 aacagcggcg gcagcatcaa cgcacagaat gacctcctgc tcgacagcac aggtagtatc
     6721 gacaacctga atgccggact gataaacgcc ggtggtgcac tgaacctgaa ggccatcggg
     6781 gatatcggca atatcagctc agtcatcagc ggtaaaaccg tatccctgga aagcgccacc
     6841 ggaaacatca gtaacctcac ccgtacagaa cagtgggcga tgaacaacgg atataaccat
     6901 ttcagcggaa cggataccgg tccgctggct gctgtcaggg caacggactc actgtttatg
     6961 ggcgcagccg gggatatcag tatcaccggt gccgccgttt ctgccggtga cagcgtgtta
     7021 ctgtccgccg gtaatgacct gaacatgaac gcgatacagg ccggagaacg tcgtcgctat
     7081 ggcgggtccg ggtggtatga aactcatgcc gtggccccca cggtcactgc cgggaacagt
     7141 ctgatgcttt ccgccggtcg tgatgtgaac agccaggctg ccggtattat ggctgaaaac
     7201 agtatggata tccgcgccgg acgggatgtg aacatggctg cggagtccac aggcacaggt
     7261 gaccacgaca gcactttcag catgaagacg gttcatgatt cggtccggca gcagggaaca
     7321 gacatgacca gtggcggtga catcacggtt actgccggac gggatatcac ctcagttgcg
     7381 accgctgtaa cggcaaaggg cgatatccgt gtgaatgccg gtcatgacat cgtactgggt
     7441 actgccacgg aaagtgatta tcactacagt gaatcagggg aaacccgtaa ccgtctcctc
     7501 agccatcaga ccacccggac catcacggaa gacagcgtca cccgtgagaa gggctccctg
     7561 ctgtcgggaa accgcgtgac cgttgacgcc ggtgataacc tgacggtaga gggttcggat
     7621 gtggtggctg accgggatgt gtcactggcg gcgggtaacc atgttgatgt tcttgctgcc
     7681 accagtacag atacgtcctg gcgctttaag gaaacgaaga aatccggtct gatgggtacc
     7741 ggcggtattg gtttcaccat tggcagcagt aagacaacgc acgaccgccg cgaggccggg
     7801 acaacgcaga gtcagagtgc cagcaccatc ggctccactg ccggtaatgt cagtattacc
     7861 gcgggcaaac aggctcatat cagcggttcg gatgtgattg cgaaccggga tatcagcatt
     7921 accggtgaca gtgtagtggt tgacccgggg catgaccgtc gtactgtgga cgaaaaattt
     7981 gagcagaaga aaagcgggct gacggttgcc ctttccggca cggtgggcag tgccatcaat
     8041 aatgcggtca ccagtgcaca ggagacgaag gagagcagtg acagccgtct gaaagccctg
     8101 caggccacaa agacagcgct gtctggtgtg caggccggac aggctgcggc aatggccacc
     8161 gcaaccggtg acccgaatgc gacgggagtc agcctgtcgc ttaccaccca gaaatcgaaa
     8221 tcacaacaac attctgaaag tgacacagta tccggcagta cgctgaatgc cgggaataat
     8281 ctgtctgttg tcgcaaccgg caaaaacagg ggcgataacc gcggagatat tgtgattgca
     8341 ggaagccagc ttaaggccgg tggtaacaca agcctggatg ccgcgaatga tgttctgttg
     8401 agtggcgctg caaacacaca aaaaacaacg ggcaggaaca gcagcagtgg cggtggcgtg
     8461 ggtgtcagta tcggtgccgg tggtaacggt gccggtatca gcgtctttgc cagcgttaat
     8521 gcggcaaaag gcagcgagaa aggtaacggt actgagtgga ctgaaaccac aatagatagc
     8581 ggtaaaaccg tcaccatcaa cagtggtcgg gatacggtac tgaacggtgc tcaggtcaac
     8641 ggcaacagga ttatcgccga tgtgggccac gacctgctga taagcggcca gcaggacacc
     8701 agtaagtacg acagtaaaca gaccagcgtg gctgccggcg gcagttttac ctttggctcc
     8761 atgaccggct caggttacat cgctgcctcc cgggataaga tgaagagccg ctttgactcc
     8821 gttgctgaac aaaccggaat gtttgccggt gatggtggtt tcgacattac agtgggcaga
     8881 catacccaac tggatggtgc ggtgattgcc tccactgcca caccggataa aaaccacctg
     8941 gataccggaa cgctggggtt cagtgacctt cacaacgaag cggattataa agtcagtcac
     9001 agtggaatca gtctgagcgg tggtggcagc ttcggggata aatttcaggg taacatgccg
     9061 ggtggcatga tatccgccgg aggtcacagc ggacatgcgg aaggaacgac tcaggccgca
     9121 gtggcagatg gcacaatcac catccgggac agggacaatc agaagcagaa tctggcgaac
     9181 ctgagccgtg accctgcgca cgctaatgac agtatcagcc cgatatttga caaggagaaa
     9241 gagcagaggc gtctgcagac agtggggctt atcagtgaca taggcagtca ggtggcggat
     9301 attgcgcgta cacagggaga actgaatgcg ttgaaggccg cgaaggaagc aaccggcgaa
     9361 acacttcctg ctaatgcaac agagaaacaa cgtcaggaat atcttgcgaa actgcgtgac
     9421 acgcaggctt acaggaatga aatggcgaag tatggcactg gtagtgaaat tcagcggggt
     9481 atccaggccg cgacggccgc gcttcaggga ctggtgggtg gtaatttagc gggtgctctg
     9541 gccggagctt ctgcaccgga actggcgcat ctgctgaaat caacagaaaa atacccggca
     9601 gtaaacgcca ttgctcacgc cattctgggc ggtgcagcag cggcaatgca gggtaataat
     9661 gttgctgccg gtgcagcagg cgccgcaaca ggagaattgg cagccagagc aattgccgga
     9721 atgctgtatc ctggcgtgaa gcaatctgac ctcagtgaag agcagaagca gacgataagt
     9781 acgctggcaa ccgtttcagc agggctggcc ggcggtctta ccggaaacag cactgcatca
     9841 gcagcagtgg gagcacagag cgggaagaat gctgttgaga ataactatct gagtaaagcc
     9901 cagaaagctc aaaaagccga tgagctggct aaatgtcaga ctgctgcctg taaggctcag
     9961 acagaagcaa aatggacggc aattgacctg gggcaggatg gtagctttgc tgcaggaatg
    10021 attgctgggg ttcctgccgg gctgtatgat gctgtggata gtattgtaaa agcaggttct
    10081 aacccgacgg aaaccctgga ggcaatgaaa gcgctgttta acagcggcga tatcttgggt
    10141 tcgttatcgg atgcggttaa gcaatcttat atagaccgta ttgaccgaat ggaagccgaa
    10201 tatcagaaag ctggtaccag cggttcgttt aatgcaggcg ttgaaggcgg taagctgatt
    10261 actgatattg ccgggctgct ggctggcggc gttggcgttg tgaaaggtgg tgcggtactg
    10321 acggagaagg ttgttgctaa ggttgtgggt aagtctgaat cagcagcggc aaaagttggt
    10381 acagatattg ttaaaacagg aaccgttttc gactcaatta aagcgactca acctgcgata
    10441 ccaggaacat ccattccaaa atcttttgaa ttacatgtta acggacaaac cgtttgggta
    10501 aacccaaatg caactaaaca tatgggcgaa tatttaacac ggaatggatt gtctcacagt
    10561 acagcagaag gaagccaagc catgctgacc agtcttcaaa gtgcggttaa agatgcattt
    10621 tcgcagggat taaaatttaa cgaaaaaatg caagttggac gctgggaact ggtatttagc
    10681 caacggtctt cagatcctta tccagtatta aagcatgcgt tgtataaata atgaaattaa
    10741 ctgtagatag cgttattaat gaacctagaa gcgtagccat tactattgat ggttatattc
    10801 ccgttgatat aaagattatt gattctaaaa agcttccgcc tttgtattgg cggggcgggg
    10861 atggcaaaaa aaacctactt gaactggctg tactaccaga aaatggtttt ttatcatcca
    10921 tcacattggt aatgatagca tcagactcaa ttcataaaac agactccttg tcagtatctt
    10981 taccaagcag tgagtgtgga gttcctgtag tgaatacaaa actgtggagc cactcagaaa
    11041 gtgatgattt tagtcgtcgt tttgttgacg attttagcct tgatattgag gtgattatat
    11101 catcagagtc tatgttatta acgattggag agaataaaaa ggtaactagc tggataaaat
    11161 gtagcgataa tttttatctc gggatagatg caggaagaaa tgtcgttcat ttgtatttgg
    11221 ataagttaac accaagtgaa gtggaaagtt tttttgaggc agtaggttag ctggaatcct
    11281 tggctatcag gtattgattt tagtttattg gtcagttagt tacagtcctg tctctgcggt
    11341 ttactgatca cctcaatcag ttctgtgacc taacgctgct ttcaagcggt tgcggtaggg
    11401 atagccgtta ctggctaccc tccacacgga tccggatgtg cgctgctaac gcatccggct
    11461 cctacgtcgg gtatttggcg tagaagcgtt gtatcggata gggtgcacgg tggtcatacc
    11521 gataacctga gtgaacaggt atgtcagcaa atcggcatgc tggtcaccat tgcttctggt
    11581 attgcggggg gacttgccgg caacagtacg gcgtctgccg gtacggggcc ctggcaggta
    11641 agaacgcggt tgagaataac tacctcagct atgacgaggc gcatgctttt gacagagaaa
    11701 tgacggcctg tcgtaaagcg ggtggagact gcggcgatat tcagaataaa tatgctgtat
    11761 taagcgcaga gaaccgacag aaattacaca ttgatgtggc cgcagatcct ctgacggcct
    11821 tgtctggtga agataaatgg aatattgagg gcggactcag tgcggcaggt cgacctggct
    11881 ggttatatgg ttcactgact aatcaggaag tgaaggatta cgtggctgaa ggcaacagct
    11941 acgacctgaa ctatctgaac agtaatacgt cgaagggtga cagggctctg gctttctttg
    12001 gggaaccgga aaattactgg ggtacggttg ccggagcggg ttcattgtta acatcatcag
    12061 ccacgctgac tgaaaaattt attagtgccg ggctgagcta tggggctaat ggtgcggtac
    12121 aaattggtac gggaaatatc ggtgataagt tcgattatct cagtttcatg atgtcaggtt
    12181 tgactggtgt aggtacagcc gggaaaggat attacgctaa ccagttgttg ggtgccggta
    12241 gcgcttacat gagcagccag attgaaggcc aggatagcac gtcgtcagtg atggggagca
    12301 tggctggtac aggccttggc tataacattg gtgcttcaat tactaataag ttagaagctc
    12361 aatacatcaa aaatcaactg ggaatggacg ccagtaaata ttcactgcaa tattcggaaa
    12421 agtctatcgg atacggtatg tatcagggcg gccaaatgag ctctatacct ggaacatttg
    12481 gtggatttgt tggttcattc gtatcagaag gtgcaagcag cgcaacgcaa aaagaagttg
    12541 atggagacaa aaaatgaaaa aacatctact acttcttatt aagttgttac ttatatctat
    12601 agctacttgc tctattggaa tagtggttag tatctggctt atagctcggg aaccaatacc
    12661 ttctgaggtg tatgtaaaat acggaataat tggcgcagta gttggcttat ggggaggtgc
    12721 tgggatttgg ttacaactct atctacaaat gcgaagatac tatcgtaaat agttgttgtt
    12781 gagaataacc tgctgggtgg cagtgaatgg ctccagacgg aaaaagccag agagcatggc
    12841 gctgatgttc tctcctgtag tgataatcct tccggtgaag cctgtaagcg ggggcaggct
    12901 gaaaataaag cttatgctgc cgcattagcg acaagtagtg tttcgctgtt acctggaagc
    12961 gcacaagcca tgtgggctct tggtgcaggt gcaaatgcag gaattggttc catggtagat
    13021 agttcagttg atcctgaaaa tgcaatcatt gcaggatggg tcaatgtaat caccatgggg
    13081 cagggctgga aagaaactgt tggatggaat gcagccggtg gtgcatttgg taactggctg
    13141 gatgggaagg atccattatc tggtgctgcg atgagtggtg gtacatcggc aataggttat
    13201 ggtgtaggta aggttgttca agggccactg gagaaagtaa ttaatcctaa ctggaaaaac
    13261 tgggaatggc tcaatgttgg tatggggatc agcaagcctc taccattaaa tccaacgcct
    13321 ggaattgctg ggaatatagg ttcttcaatt ggtacagaag gatcaggagc tataatccaa
    13381 gaacagttaa aaaatcaaca ggagaagaaa taatgaagtg tcaatctctc cttatgcgtt
    13441 ttttagtgac tgtacttata tggtttattg ccatatttat catgtcggta atgatgtttt
    13501 tcttcatcag agtgtttgca ttttattgga ttggtggcga ttttttattc tcatatattg
    13561 atgttatgaa atctttaaaa atagcagtgt attgctctct gctatgtagc atagggagtt
    13621 ggggcttata tcgaagtaat aaaaaaaaca atagataata gaattaatcc cgcccttaat
    13681 ccggcgggat tttagttgag aataactcgc tgagtgctga tcagatcgat aactttgcgg
    13741 cgagggcgaa aggttgtgaa gcacgtggcg actgcaaaca gattgtaaag gagatggagg
    13801 acctcagcct taagcaacag caggaaatga tagctgtctg tgcaacaaac cctgcagcct
    13861 gcaaagagaa atacggcgat ataccagcta aaggaatgct tgtacgagaa gcgatagatc
    13921 gtgtgttagg tgcagatgta ccgtctgcaa tgaagaatga tatgtcttcg ttgttagctc
    13981 agcagatcga agcggaaggt gttgttacca gtactgaatt tgccagtcag atacaaaatt
    14041 gttacggtat agacaagcaa caggctgaaa tccttgctgt cgcagcaccg ggagccgtga
    14101 caggtgggat gaggaaatca ggtacttcaa cggcaagtaa aaacatcgtt gtggttgatt
    14161 ctggtaagaa aggggcctgg aaccaagcaa tgaataagcc ggaaccgaat accgtttata
    14221 aggtcgatgg gaataaaaca ttccagactg atgcattggg aagaactagt tcagcagaag
    14281 ggatactagt tgcttcgaaa agcgacagaa acacttatca gcaatgcaag gccgggaaat
    14341 gtggtagctc tggtgatgaa ggtggtcatt taattgccag tatttttaat ggtcctggcg
    14401 aaaaactcaa tcttgttcct atggatggca acctgaataa aggtgtatgg aaacagatgg
    14461 aaaacacatg ggctaatgct ttgaaagatg gcaaacaagt taatgttaaa atagaacctg
    14521 tttacactgg ggagaataag cgtcctgata gctttagtgt aacaatactc tattgacgga
    14581 ggccgtcctg ttatcaaaga catcagcaac acacctggag gggtaaaatg aacgaattag
    14641 atgatctgca taataaaata ggtcagttat tagtggatgc cggtcctgcg aatgcgatga
    14701 agatcattgc tcgtgctaaa ttatcactag atggtgagtc atgtgagtat gagtatgatt
    14761 atcttgatca agagggagat gaagactggt tcgttcctga taagttagcc agtcacgatc
    14821 ttagactact gttagttaaa atgagggatt tttacatcca aaataatatg actaacggga
    14881 aaccagcatg gataggttgt gaaataatcg ttgatatacc agaagaaaaa attagcataa
    14941 actttcaata tgatgattta actgtgatcc cggccccagc accgggctca ccacaatgcc
    15001 cgtagcgtgt gcggtggaaa aaagcgcgtc ggggcaaaaa ttggcgggca gcgaaacgca
    15061 acaggataaa tgattgtaac ctactgaaaa aaaggaaaaa cagttttctt caccacgatg
    15121 cgcgtcagag agagttgttg ttgagaataa tgcgctcagt aaggacaaga tctttgacat
    15181 taatccaatg ctgaaaattg gggttgagga tgttgatggg gagttgctga aaggtggcgg
    15241 tggaattgct aatggacggc cctcacatag acaatcagaa aaggatgttg gtaaagactt
    15301 aggcgcagga tggagagagc aggttagcta taaagatggg aaagaagtac cttacggtac
    15361 gaaaggaagt acccgacctg attggtgtaa tggtaataca tgtggtattg aggttaaaaa
    15421 ctataacatt gctacaaata ttaatggttt aataaataat gtttctaaac aggctattca
    15481 tcgtgctgag aatctgccag cgggaatgca acagagaatt attattgatg tgcgtggtca
    15541 aatagttacc ccaaatcaag aacgtactat aattaaaggt atagtcgaga gatcaaatgg
    15601 ggttattgct ccaacatcta tcagatttaa gaggtaagta tagcgtatga aaagagttgg
    15661 attttgtggc gggagttcat tttttgagct tggttcagct tctgatatgc ttaatttctt
    15721 tagctatcta aataaattat ctcgaactga aagagataga tatctgttgg agaggattta
    15781 tttcaaatat attaagtttg atgagataga tgaaagctgc gcccttttaa atgagttaaa
    15841 aaatctttgc tctgaggact ttatccataa attttcaaag tattttgaaa gtattaaatg
    15901 gtgttctgaa tcagctaaag agttttatga ggactggaat gtatatcaag aaataaaaat
    15961 aataattaca gaaatgccat attgtatatc tgaaatggaa aggcctaaag aagaatatga
    16021 tgcacttact ttaagtgatg ttcccttttg gttacggtaa aaaacactaa caatatgagt
    16081 aagctggaac gttaataaat ccgtatgcaa ggtatcgttc cggtgaacta tgcggacaga
    16141 gaagcaggtg gtctcaacac tggcaacggt tgctgccggc ctggccggtg gcctggtggg
    16201 agactcgggg gcttcagcgg tagccggcgc acagtcaggt aagacgactg ttgaaaacaa
    16261 tatgctgaac gtgatagcca ctgaaacagc agctaatacg gcagcagcaa tagcttgtgc
    16321 tacaggtaat gccagtaagg ataccgggaa tgataatagc tgggatattg gtggtggttg
    16381 tgaaggctca cgggaacagt gtgctgtacg tgatccgagt cgcgatggca cccggggacc
    16441 ggggcatgtg ctgaatggcg acaatacaga cgaaaacaaa cagccgaatc tgggtaaaga
    16501 cgtagcgagc gctacagaca aggagaaagc tgagcttggt ggtgcagggg ctggaacacc
    16561 ggggggatgg gagccgcagg atgaggagaa cgccaggaat aatgaatcaa tagaacaacg
    16621 taatgagaaa acctcatcag aaaacgtacc taatagttct gaaaagttac cttgggactc
    16681 ttggcaaaat tatcgaaagg ttacagtaga tgggcggcaa tatgcacaaa taggtcatcg
    16741 tttgtattca caacatgctg ttgatagaat gcagccatct ggtttaggtt ctccagccgg
    16801 cacagttggc ccagggagaa atataacgcc gaatatggtt gaaagtgtta tcaaagaagg
    16861 aactcctcaa aatagtgtcg ttaatggcgt aactagaacg acttattgga gtggtgacgt
    16921 aggtgtagtc actgaaaata acagtaatat tattgttact attcttcgca ggagtgggca
    16981 atgagttgga tttatcctga ggtgatcgag aggttacaac actcttgtaa aaactttctt
    17041 gaagggaaaa taacggtaca aagtattcaa tcagaaattt atgctgcgga aagccaaatt
    17101 gttgctgttg aggaaaagtg gctccataca atgttattta atgcggagaa tgagatcgaa
    17161 ttgcttttgt atacagttga ggaggagcaa ttggttagtt ctgtaatacc gatagtcaat
    17221 aatattttaa gcaaaatcaa atagacttta actaccagct agttcagttg gctggttttt
    17281 ttgcttttcc atctttgaca aggaaaaaga gcagc
//
LOCUS       DAZUDJ010000086        16984 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.086, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000086 DAZUDJ010000000
VERSION     DAZUDJ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16984
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.086"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..197
                     /locus_tag="ACHY1N_004154"
                     /pseudo
     CDS             1..197
                     /locus_tag="ACHY1N_004154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502670.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(560..1753)
                     /gene="tyrB"
                     /locus_tag="ACHY1N_004155"
     CDS             complement(560..1753)
                     /gene="tyrB"
                     /locus_tag="ACHY1N_004155"
                     /EC_number="2.6.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HFS4046362.1"
                     /translation="MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIP
                     QLQAVAEAEARLNAQPHGASLYLPMEGLNSYRHAIAPLLFGADHPVLQQQRVATIQTL
                     GGSGALKVGADFLKRYFPESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRF
                     NDLLATLKTLPARSIVLLHPCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGF
                     GAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVLCEDAEAAGRVLGQL
                     KATVRRNYSSPPNFGAQVVAAVLNDEALKASWLAEVEEMRTRILAMRQELVKVLSTEM
                     PERNFDYLLNQRGMFSYTGLSAAQVDRLREEFGVYLIASGRMCVAGLNTANVQRVAKA
                     FAAVM"
     gene            complement(2006..3085)
                     /gene="alr"
                     /locus_tag="ACHY1N_004156"
     CDS             complement(2006..3085)
                     /gene="alr"
                     /locus_tag="ACHY1N_004156"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFS4046363.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGIIKPVLLLEGFFDARDLPTISAQHFHTAVHNE
                     EQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHF
                     ARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVS
                     PLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYVD"
     gene            complement(3138..4553)
                     /gene="dnaB"
                     /locus_tag="ACHY1N_004157"
     CDS             complement(3138..4553)
                     /gene="dnaB"
                     /locus_tag="ACHY1N_004157"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFS4046364.1"
                     /translation="MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
                     AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKT
                     AGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASL
                     SRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREH
                     GGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            4636..5619
                     /gene="qorA"
                     /locus_tag="ACHY1N_004158"
     CDS             4636..5619
                     /gene="qorA"
                     /locus_tag="ACHY1N_004158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HFS4046365.1"
                     /translation="MATRIEFHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFID
                     TYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIKAGDRVVYAQSALGAYSSVHNIN
                     ADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGTAQKAQSALKAGAWQVINYREEDLVERLKEITGGKKVRVVYDSVG
                     RDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILESRATQGSSLLIP"
     gene            complement(5785..6027)
                     /gene="pspG"
                     /locus_tag="ACHY1N_004159"
     CDS             complement(5785..6027)
                     /gene="pspG"
                     /locus_tag="ACHY1N_004159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HFS4046366.1"
                     /translation="MLELLFVIGFFVMLMVTGVSLLGIIAALVVATAIMFLGGMLALM
                     IKLLPWLLLAIAVVWVIKAIKAPKVPKYQRYDRWRY"
     gene            complement(6161..7198)
                     /gene="dusA"
                     /locus_tag="ACHY1N_004160"
     CDS             complement(6161..7198)
                     /gene="dusA"
                     /locus_tag="ACHY1N_004160"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0002943 - tRNA dihydrouridine synthesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HFS4046367.1"
                     /translation="MHGNSEMQKINQTSAMPEKTDVHWSGRFSVAPMLDWTDRHCRYF
                     LRLLSRNTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEA
                     RGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDD
                     QDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDF
                     PHLTMSINGGIKSLEEAKAHLQHMDGVMVGREAYQNPGILAAVDREIFGSSDTDADPV
                     AVVRAMYPYIERELSQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADINVL
                     EHALKLVADKR"
     gene            complement(7561..8268)
                     /gene="yjbM"
                     /locus_tag="ACHY1N_004161"
     CDS             complement(7561..8268)
                     /gene="yjbM"
                     /locus_tag="ACHY1N_004161"
                     /inference="COORDINATES: protein motif:HMM:NF022352.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2713 family protein"
                     /protein_id="HFS4046368.1"
                     /translation="MWVNKYIDDCTDEDLNDRDFIASVVDRAIFHFAINSICNPGDNK
                     DATPIEQCTFDVETKNGLPSTVQLFYEESKDNEPLANIHFQAIGSGFLTFVNACQEHD
                     DNSLKLFASLLISLSYSSAYADLSETVYINENNESYLKAQFEKLSQRDMKKYLGEMKR
                     LADGGEMNFDGYLDKMSHLVNEGTLDPDILSKMRDAAPQLISFAKSFDPTSKEEIKIL
                     TDTSKLIYDLFGVKSEK"
     gene            complement(8292..8546)
                     /gene="yjbL"
                     /locus_tag="ACHY1N_004162"
     CDS             complement(8292..8546)
                     /gene="yjbL"
                     /locus_tag="ACHY1N_004162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YjbL"
                     /protein_id="HFS4046369.1"
                     /translation="MLKIIPGATGYFNKTLNSNQFDNEDTIKDKLDNRGSIKGKLNNI
                     YGKSIDYAALRHRDIIIAKIDLFIQRITHNLWHARKKMCF"
     gene            8864..9379
                     /gene="zur"
                     /locus_tag="ACHY1N_004163"
     CDS             8864..9379
                     /gene="zur"
                     /locus_tag="ACHY1N_004163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418470.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HFS4046370.1"
                     /translation="MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISA
                     YDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFI
                     CDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
                     DHSVQVKKKPR"
     gene            complement(9421..9630)
                     /gene="yjbJ"
                     /locus_tag="ACHY1N_004164"
     CDS             complement(9421..9630)
                     /gene="yjbJ"
                     /locus_tag="ACHY1N_004164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFS4046371.1"
                     /translation="MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVVDWETRNEYRW"
     gene            complement(9746..11071)
                     /gene="dinF"
                     /locus_tag="ACHY1N_004165"
     CDS             complement(9746..11071)
                     /gene="dinF"
                     /locus_tag="ACHY1N_004165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HFS4046372.1"
                     /translation="MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVY
                     LGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGAL
                     IALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
                     PVILLVVGNILNIVLDVWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGI
                     SGEMLKTAWRGNFRRLLALNRDIMLRSLLLQLCFGAITVLGARLGSDIVAVNAVLMTL
                     LTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGE
                     HIIALLTSLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAA
                     GFALTLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT"
     gene            complement(11144..11752)
                     /gene="lexA"
                     /locus_tag="ACHY1N_004166"
     CDS             complement(11144..11752)
                     /gene="lexA"
                     /locus_tag="ACHY1N_004166"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFS4046373.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL"
     gene            complement(11862..12230)
                     /gene="dgkA"
                     /locus_tag="ACHY1N_004167"
     CDS             complement(11862..12230)
                     /gene="dgkA"
                     /locus_tag="ACHY1N_004167"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFS4046374.1"
                     /translation="MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVV
                     IACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LIAIIVAVITWCILLWSHFG"
     gene            12401..14824
                     /gene="plsB"
                     /locus_tag="ACHY1N_004168"
     CDS             12401..14824
                     /gene="plsB"
                     /locus_tag="ACHY1N_004168"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418465.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004366 - glycerol-3-phosphate
                     O-acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HFS4046375.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESI
                     KLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
                     RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDST
                     VPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMA
                     AIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQ
                     DDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLT
                     IESATQGEG"
     gene            complement(14979..15851)
                     /gene="ubiA"
                     /locus_tag="ACHY1N_004169"
     CDS             complement(14979..15851)
                     /gene="ubiA"
                     /locus_tag="ACHY1N_004169"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008412 - 4-hydroxybenzoate
                     octaprenyltransferase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HFS4046376.1"
                     /translation="MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVV
                     LVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIL
                     QIGVLALMAIIGELNGLGWGYYWSIVVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(15864..16361)
                     /gene="ubiC"
                     /locus_tag="ACHY1N_004170"
     CDS             complement(15864..16361)
                     /gene="ubiC"
                     /locus_tag="ACHY1N_004170"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008813 - chorismate lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HFS4046377.1"
                     /translation="MSHPALTQLRALRYFKEIPALDPQLLDWLLLEDSMTKRFEQQGK
                     TVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSG
                     PELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            complement(16584..>16984)
                     /locus_tag="ACHY1N_004171"
     CDS             complement(16584..>16984)
                     /locus_tag="ACHY1N_004171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046378.1"
                     /translation="RSTDDMIKANAWYLYKEWIRSDDVSPLFIEIEDNLRTFNTNELT
                     RKDNIFILFSSADDGPVMVVSSQRLHDMLNPTKDTNWNSTCIYKSRHKMLPINLTQET
                     LFSSKSHGKYALFPIFTASWRATRIKNIGI"
BASE COUNT         4449 a         4436 c         4006 g         4093 t
ORIGIN      
        1 gagaagaagt atcaagttct attgcaagta aagtttttca cgcatttatt gatttagtta
       61 acaaaatcag gggtaagaaa gactttatgt atatttgcac gctttgctgt tttgccgagg
      121 aggttaaagg tgattattct cattacagga cctttttatt tgatattggt aatcaatata
      181 aggttaaact tacacaaagc ggaaaaaaag agctctcttt aactttagaa tttaacgata
      241 ctataattga atctcagaaa gtcacaggca ataaggcaaa gcatattctt gaggatatag
      301 aaaaattcta tcgtaacaaa cccgatactt attattaaat ttaataatag ttagatgtgc
      361 agaaattatt actccaccca aaaaaacagg ataaggaatt ccagataatt aggataagct
      421 taacaataaa agaactaata acgtttatta tctctcacgt agaacgatgg catcaaaaaa
      481 atcatctata aagaaagagt gaaagcgacg acagtttaat ttcactgcag gctgggtagc
      541 tccagcctgc tttcctgcat tacatcaccg cagcaaacgc ctttgccaca cgttgtacat
      601 ttgccgtatt taacccggcg acacacatgc gaccgctggc gatgagatag acaccaaatt
      661 cttcacgtag tcggtcaacc tgagcggcac ttaaaccggt ataactgaac atgccgcgct
      721 gattaagcag ataatcgaaa ttgcgttctg gcatctctgt gcttaatacc ttcaccaatt
      781 cctgacgcat tgccagaatg cgagtacgca tctcttctac ttccgccagc cagctggctt
      841 tcaatgcctc gtcattcagc actgcagcca ccacctgcgc accaaaattc ggcgggctgg
      901 agtagttgcg gcgaactgtt gctttcaatt gccccagtac gcggccagcg gcttcggcat
      961 cttcacacag aacagaaagt ccgccgacgc gctcgccgta aagggagaaa attttcgaga
     1021 acgaattgct caccagagcg ggtaatccag cgctggcaat ggcgcgaata gcgtaggcat
     1081 cctcttccat accggcacca aatccttgat aggcaatatc gaggaatgga ataagctcgc
     1141 gggctttgag aatttcaatc accgcatccc actgatcatt agtgagatcg gcacccgttg
     1201 ggttgtggca acatggatgc agcaacacaa tactgcgggc aggtaatgtt ttcagcgtcg
     1261 ccaacaggtc attaaagcgc acgccgttag tcgcttcgtc ataccagggg taagtactca
     1321 cttcgaatcc agccccggcg aatattgcta cgtggttttc ccaggtagga tcgctgaccc
     1381 agacgcctga ttccgggaag tagcgtttca ggaaatccgc gcccactttc aatgcccctg
     1441 agccgccaag ggtttgaatg gttgctacgc gctgttgttg cagtactgga tggtccgcac
     1501 caaacagcag cggcgcaatg gcatggcgat agctgttaag cccttccatc ggtaaataaa
     1561 gcgaagcgcc atgaggctgc gcattcaggc gcgcttccgc ctccgccacg gcttgcagtt
     1621 gtggaataat tccgtcttcg ttgtagtaca gaccgatact taaattcact ttgtcgctgc
     1681 gagggtcttc tttaaaacgc tccataagcg taagaatcgg gtcgccagcg taggcgtcaa
     1741 ctttttgaaa cacgcgatgg ttctccaggt ttacgggcag gtggttaaaa cacaataaac
     1801 cggaagaagg cgaagatcga gtggatgttc aggagcgaac ggcaattagc aacagagtga
     1861 gactcatgac aaacgtacat ccgccagagg cacgaccttt ataagagcat gaaagaacat
     1921 caacttattg aatttttagg attttattgg ccggataagg cattcacgcc gcatccggca
     1981 cagacaatca aatattacag aacgattaat ccacgtattt catcgcgacc cttgaagtca
     2041 ggcgcgtaat aagttcgtaa gcgcttactt tcgtcatttc agcgatacgt tctacgggca
     2101 aaccttcgcc ccataaaatg accggatccc cggctttgtc ctgcgcttgt ggacctaagt
     2161 ctacgcagat catatccatc gccacgcgcc cgacaatcgg tacttcgcga ccgttcacca
     2221 gcactggcgt accggacggc gcggcgcgcg gataaccatc gccatagccc atcgcgacta
     2281 cgccaagacg ggtatcacgt tcgcttaccc aggttccacc ataaccaaca ggttctccgg
     2341 ctttatgctc acgcacggca atcaggctgg aggttagtga catcactggc tgacagccaa
     2401 aatcggcacc ggtggagcga tcttccagcg gcgagacgcc ataaagaatg atgcccgggc
     2461 gcacccagtc aaaatgcgac tgtggccaca gcagaatgcc acccgatgcg gcaatggaac
     2521 gttgaccagg tttgccttcg caaaaggtat taaagatagc gagttgtttc tcggttgcgc
     2581 cacattttgg ttcatccgcg cgcgcaaaat ggctgacgat attcaccggc tgacgaacgt
     2641 ttttgcactg ggtcaggcga tgataaaacg cctcagcctg ttccggcctt acgcccagac
     2701 ggtgcatacc ggtatcgagt ttcatccaga cggtaaccgg ctcgtccagg ctagcctctt
     2761 ccagcgcagc cagctgttct tcgttatgca cggcggtatg aaaatgttgc gcagaaatcg
     2821 tcggcagatc tctggcatca aaaaagcctt cgagtaacag tacaggtttg atgattcccc
     2881 ccgcacgcag tcgcagagct tcttcgagac gggctacgcc aaaggcgtca gcatcgggga
     2941 gcgttcgcgc ggtctcaaga agaccgtgac cataagcgtt cgctttcacc accgcaacca
     3001 ttttactggc aggggccagt tcacgaagac gttgcaggtt gtgtcgcaga gcgcggcggt
     3061 taatcacaac agttgccgct tgcatttgtg ttccttgata agtgtttgct ttaattacct
     3121 aattcataaa ataattatta ttcgtcgtcg tactgcggcc ccgcatagtt gtcgaagcgc
     3181 gaccattgac cgttaaaggt caggcgtacc gtcccgattg ggccgttacg ttgtttaccg
     3241 ataataattt ccgcgatgcc ttttaaatca ctgttttcgt gatacacctc atcacgatag
     3301 ataaacatga tcaagtccgc atcctgctcg atagagccag attcacgcag gtcggagttg
     3361 accgggcgtt tgtcggcacg ttgttccaga gaacggttca actgggacag cgccaccacc
     3421 ggcacgttca gttctttcgc cagtgctttc agcgagcgag agatttctgc aatttccagc
     3481 gtacggttat cggaaagcgc cggtacgcgc atcagttgca ggtagtcgat catgataagc
     3541 ccgatgccgc cgtgttcacg ggcaatacgg cgtgcgcggg aacgcacttc cgttggcgtc
     3601 aggccggagg agtcatcgat ataaatattg cgtttttcga gcaaaatacc catggtgccg
     3661 gaaatgcgcg cccagtcttc atcatcgagc tgcccggtac ggattttagt ctggtcaacg
     3721 cgcgacagcg acgccagaga acgcatcatg atctgttctg atggcatctc cagcgagaag
     3781 ataagtactg gtttatcctg caacatcgcc gcgttttcga cgaggttcat cgcaaatgtt
     3841 gttttaccca tcgacggacg cgcggcgacg atgatcaaat ccgacggctg caagccagcg
     3901 gtttttttgt tgagatcgtc ataaccggtg tttactccgg taacgccatc gtgtggctgc
     3961 tgaaacaact gctcaatacg cgccacggtt gcgtcgagca catcggcgat gttcttcggc
     4021 ccttcgtctt tgtttgcacg actttcggca attttaaaga cgcgggattc agcaaggtcc
     4081 agcagatctt cgctggtacg cccctgcgga tcaaaaccgg cttcagcaat ctcattcgca
     4141 accgagatca tctcacggac aacggcacgt tcacgcacga tgtcagcata agcactgatg
     4201 ttcgccgcac ttggcgtatt ttttgacagc tctgccagat aagcaaaacc accgacgcta
     4261 tcgagttgcc cctggcgttc cagcgattcc gcaagggtaa tcagatcgat aggactaccg
     4321 ctttcctgca aacgcgccat ttcagtaaag atatggcggt gtgggcgggt gtaaaaatcg
     4381 tctgccacca cacgctcggc tacatcgtcc cagcgttcgt tatccagcat taaaccgccc
     4441 aacaccgact gctccgcttc gatcgagtgc ggaggcactt tcagcccggc aacttgtgga
     4501 tcgcgttcgc ggggttcagc ctgctgtttg ttgaagggtt tatttcctgc catagtgaat
     4561 ggagttaccg agataaagaa tgggtcgaaa ctttaccata tgaagcagac cctgacgata
     4621 cgttctggag gacacatggc aacacgaatt gaatttcaca agcacggtgg cccggaagta
     4681 cttcaagccg tagagttcac tcctgccgat ccggcagaga atgaaatcca ggtcgaaaat
     4741 aaagccatcg gcatcaattt tatcgacacg tatatccgca gcggccttta cccgccgcca
     4801 tcactaccca gcggattagg taccgaagcg gcaggcatcg tgagtaaagt cggcagtggt
     4861 gtaaagcata ttaaggcagg cgatcgtgta gtctatgcgc agtcggcgtt aggcgcttac
     4921 agctctgtgc ataacattaa tgcggataaa gcggcgattc tgcctgcggc aatttctttt
     4981 gagcaagctg cagcatcttt cctgaaaggc ttaacggttt attatctgct gcgcaaaacc
     5041 tatgaaatta aacccgatga gcagttcctg ttccacgcag cagctggcgg cgttggcttg
     5101 attgcctgcc agtgggcaaa agccctgggc gcgaaactta tcggcaccgt aggaaccgcg
     5161 caaaaagcgc agagcgcgct aaaagcgggc gcgtggcagg ttattaacta tcgtgaagag
     5221 gatctggtcg agcggttaaa agagatcacc ggcggtaaga aagtgcgcgt ggtgtacgat
     5281 tccgtgggca gagacacctg ggaacggtcg ctggattgcc tgcaacgccg cggcttaatg
     5341 gtcagttttg gcaactcatc aggtgcggtt accggtgtga acttaggcat tctcaatcaa
     5401 aaaggctcgt tgtatgtgac acgcccttcc ctgcaaggct atatcaccac gcgggaggaa
     5461 ttaaccgagg ccagtaatga actgttctct ttaattgcca gcggtgtgat taaggtcgat
     5521 gtcgccgagc agcagaaata tccgctgaag gatgcgcagc gtgcgcatga gattctggaa
     5581 agccgggcga cgcaaggttc cagcctgttg attccataaa agaaataggg cttccacctg
     5641 ggaagccctt tctttttata gttcggctgt atgtagggta cagcacgatg aatctgttag
     5701 aggcgcaata gtgacagatt tgattatcaa ttcctatttt gttctaagga taaaacctta
     5761 ggttgtgatc atccgcacaa tcccttagta acgccagcgg tcataacgct gatatttcgg
     5821 cacttttggt gctttaatcg ccttaataac ccacaccacc gcaatcgcca gtagtaacca
     5881 cggcagcaac ttaatcatca atgccagcat accgccgagg aacataatgg ccgtcgccac
     5941 aaccagcgcg gcgataatgc ccagcaacga aacgccggtg accatcagca tgacaaaaaa
     6001 gccaatcaca aaaagtagtt ccagcatgat gctctcccaa atatgaaatc tcttgctggc
     6061 attacaagaa tcatgccaaa aataatctat tgatttaaca gcaaaacgcc ccgcgacggt
     6121 gcgcagggcg tggtgaattt gactactttt tggtgaaaag ttaacgctta tccgccacca
     6181 gtttgagcgc gtgttccagc acattaatgt ctgcacccgc tttatgggca ttttcactta
     6241 aataacgccg ccactgccgc gcgccaggaa taccctggaa caagcccaac atatgccggg
     6301 taatatggcc gagatacgtc ccctggctga gttcacgctc aatgtacgga tacatggcgc
     6361 gcactaccgc caccggatcg gcatcggtat ccgaggaacc aaagatctcc cggtctactg
     6421 ccgccagaat acccggattc tgatacgcct cgcgcccgac catcacgcca tccatatgtt
     6481 gcaggtgtgc tttggcctct tccagcgact tgataccacc gttaatcgac attgtcagat
     6541 gcggaaagtc acgcttcagt tgatacacac gcggataatc gagcggcggg atttcacggt
     6601 tttctttcgg gcttaacccc gaaagccagg ctttacgtgc gtggatgata aacatctcac
     6661 actcgccttt gccggaaaca gtgttgatga aatcgcagag aaattcatag ctgtcctggt
     6721 catcgatgcc aatacgcgtt ttcaccgtca ctggaatcga caccacatcg cgcatcgctt
     6781 tcacacagtc ggcaaccagc tgcgcattac ccatcagaca cgcaccaaac atgccgttct
     6841 gcacccggtc agacgggcag ccgacattca ggttgatctc atcatatccg cgcgcttctg
     6901 ccagctttgc acactgcgcc agcgccgccg gatcgctacc gcccagttgc aacgctaccg
     6961 gatgttcttc ttcactgtac gccagataat cacctttacc gtgaataatc gcccctgtgg
     7021 tcaccatttc ggtatacagc aacgtattgc gggaaagcag acgcaagaaa tagcggcaat
     7081 gtctgtccgt ccagtcgagc attggtgcaa cgctaaaccg accactccag tgaacgtcag
     7141 ttttttcagg cattgcgctg gtttggttga ttttttgcat ttcagaatta ccgtgcattt
     7201 tcaaatgtag agattatttt atcgatatat catggggtta tgttattcag catcactatt
     7261 caggaggctc aatagcgggg tactatacca taacaacagg aagcgcctgt ctcattgcaa
     7321 aagaaaattg agatcctctc aaggcatgaa gctctcacga agtgatggaa ataatcttat
     7381 tagccgttaa ctttgttaag gccaatgata aacaatccag gttcgacgat aaataaaaaa
     7441 tcacacatta aactctggtg atatatctcc ctgctaatag cattgataga gaaaaaagaa
     7501 cccaataaat attgggtcct tttatataat gccttccata ctatcgaaga acttcacata
     7561 ttatttctcc gatttaaccc cgaacaaatc ataaattaat ttagaagtgt ctgtaagtat
     7621 tttaatctct tcctttgagg ttgggtcaaa cgacttcgcg aagctaatta attgtggtgc
     7681 agcatctctc attttgctta aaatatcagg atcgagcgtt ccttcattca ccagatgtga
     7741 catcttatcc agatagccat caaaattcat ttctccccca tcagccagac gcttcatctc
     7801 tcccaggtac ttcttcatat cacgttgaga taatttttca aactgagctt tcaggtagct
     7861 ctcattattt tcattaatat acactgtttc tgataaatct gcgtaggcac tagaatatga
     7921 aagtgaaatt aacagcgaag caaataattt taagctgttg tcatcatgtt cctggcaggc
     7981 attaacaaac gttaaaaaac cagaacctat tgcttgaaaa tgtatattcg ctaaaggttc
     8041 attatcctta gattcctcat aaaatagctg aaccgtggag ggaaggccat tcttagtttc
     8101 tacatcaaaa gtacattgtt caatgggagt cgcatcttta ttatccccag gattacatat
     8161 actattaatc gcgaaatgaa aaatagcccg gtcaacaact gatgcaataa agtcacgatc
     8221 gtttaaatcc tcatcagtgc aatcgtcaat atacttattg acccacattt tgagatcatt
     8281 tatttgctca attaaaaaca cattttttta cgtgcatgcc ataaattatg cgtgattcgt
     8341 tgaataaaca aatctatttt tgcaataatt atatcccgat gacgcagcgc tgcataatca
     8401 atagatttac catatatatt atttaattta cctttgattg aacctctatt atctaattta
     8461 tctttgattg tatcttcatt atcgaattga tttgaattga gtgttttatt aaagtatcca
     8521 gttgcaccgg gtattatctt caacatgatt catctacctt ttttgtcgta ccgtgtcctc
     8581 cttataattc ttttgccatc tggtcactat caaaaatcgc tcataatttc tgaactacag
     8641 gtatgcgttt aaacccagtt aaataaatag cgagttaact tgaagcaatt tatttaaaaa
     8701 tgaattatta attattatcg tgttgataat ggtacgacaa ggcaacacaa caccttacct
     8761 acaaaacaga aaatcaacat tacggcaaca ataagggttc tcggtgtttt tcctggaaca
     8821 tggtaaagta aggacattct taacccccac tttgaggtgc ccgatggaaa agaccacaac
     8881 gcaggagtta ttagcgcagg ctgaaaaaat ctgcgcgcag cgtaatgtgc gcctgacccc
     8941 acagcgcctg gaagtgttgc gcctgatgag tctgcaggat ggcgctatca gcgcttatga
     9001 tctgcttgat ttactgcgcg aagctgaacc gcaagccaag ccgccaacgg tttatcgcgc
     9061 gctggatttt ctgcttgagc aaggttttgt gcataaggtg gaatccacca acagttatgt
     9121 gctctgtcat ctgttcgacc agcccacgca tacgtcagcc atgtttatat gcgatcgctg
     9181 cggcgcggtg aaagaagagt gtgcagaagg cgtggaagac attatgcata cgctggcggc
     9241 aaaaatgggg tttgccctgc ggcataatgt gattgaagca catgggctct gtgcggcatg
     9301 cgtggaagtg gaagcgtgtc gtcatcctga acagtgccag catgatcact ctgtgcaggt
     9361 gaaaaagaaa ccgcgttaag agggcgtaca tccttgtaca cgtcgggcag gagggattaa
     9421 ttaccagcga tattcattgc gggtttccca atccacgacc tctttttctg cctgatcttt
     9481 ctgataacca taacgttcct ggattttacc gaccagttga tcacgtttac cttcaatgat
     9541 cgtcatatca tcatcggtca gtttgcccca ttgctctttc actttacctt taaactgttt
     9601 ccagttaccg ccggcttcat ctttattcat aatcaagacc tcatcgttag gttgtgaatg
     9661 agagtacgtt cacttttctt ctgaacgtga gattaagtgt agtcagcaat ttggcttagg
     9721 ataatttatt cagaattttt aaccgtcacg ttgcggcaaa ccaggtaccg ttgcgccagt
     9781 gacgccgcca gatagccgcc agagaaagcc cgcgcaacgc cagaaagacg gttaatgcca
     9841 gccacaaacc atgattaccc agccacggca gcgtaaggag cgtcagcgca aaacctgcgg
     9901 cggccaccgc catactgtta cgcatttcgg cggcacgcgt tgcgcctata aacatgccgt
     9961 ccagcagata acaccagacg ccaaccaacg gcaaaatcac ctgccagata agatagcggt
    10021 cagccagctg ctgaatctgg gttaacgacg tcagcaacgc aatgatgtgt tcccctgcca
    10081 gcaaataaac caccgaaaac agtaacgcta caatccccga ctggcggcac gctgcccgcc
    10141 atacatccag caactggcta ccgtcgcgcg caccgtatgc ctgaccggag tgcgcttcaa
    10201 ccgcgtaggc aaaaccatca agcgcatagg cggtaaaggt gagtagcgtc atcagaaccg
    10261 cgttaacagc gacaatgtca ctccccagtc gcgcaccaag tacggtgatc gcgccgaaac
    10321 agagttgcaa caacagcgaa cgcagcatga tatcgcggtt aagcgccagc aagcgacgga
    10381 agtttcctcg ccaggcagtt ttcagcattt cgccggaaat tccgcgtagt ttgaggattt
    10441 tacgcaccat tagcagacca atcagcaatg ttgcatattc cgcaataacc gtcgccagcg
    10501 ccgcgccctg cacgttcata tgcagcccca tcaccagcca gacatccagc acaatgttga
    10561 ggatattgcc gaccactaac aaaattactg gcgcacgggc atattgcacg ccgagtaacc
    10621 aaccgagtaa taccagattc gccagcgacg ccggagcgct taaccagcgg atttcaagaa
    10681 agcgccgcgc ctgttccagg accgcttcac taccgccaac aatatgcagc gccagatcga
    10741 taatcggtgt acgcagcagc gcaattaacg ccccagcccc caacgccaac agcaacggtt
    10801 gcaccagcgc acgggctaat gcctgaggat ttttggcacc ataagcctgc gcagtcagcc
    10861 cggtggtgct catgcgtaaa aacagcaaca gcataaagag aaagctggtc gccgttgcac
    10921 caaccgccac gccgcccaaa taaaccgggc tatcaagatg accaattacc gccgtatcga
    10981 ccagtcccag caacggaacg gtgatattgg agaaaatcat gggtaaggcg agatgccaga
    11041 gtgctttatc agatgaagtg aggaatgcca tgcagacaag cctgatgaag agagatgaaa
    11101 aacaaaccgc gacgcctggc ggcatcgcgg tctcagagat atgttacagc cagtcgccgt
    11161 tgcgaataac cccaaccgcc agcccttcaa tggtgaagct ctgctgacga aggtcaacga
    11221 caattggttt aaactcgcta ttttctggca acagttcgac tttattgccc tgttttttca
    11281 ggcgcttaac ggtaacttcg tcatcaatac gtgcgacaac gacctgaccg ttacgtacat
    11341 cctgagtttt atgcactgcc agcaagtcac catccataat gccgatatct ttcatcgaca
    11401 tcccgctgac gcgcagcagg aaatcagcat tcggcttgaa caaggaagga tcgacctgat
    11461 aatgaccttc aatatgctgt tgcgccagaa gcggttcacc ggcagccaca cgacctacca
    11521 gcggcaaccc ttcttcctct tcctgcaaca gacgaatccc gcgtgatgcg ccggaaacaa
    11581 tttcaataac gcctttgcgt gccagcgcct tcagatgttc ttcagccgcg tttggggaac
    11641 ggaaccccaa acgctgcgcg atttccgcac gcgtcggcgg catacctgtc tggctgatgt
    11701 gatcacggat gagatcaaac acctcttgtt gcctggccgt taacgctttc attccgcccc
    11761 ctgggtgtat atacagttat gctgtgagta tatacagcaa aaggcgattt tggaaccata
    11821 aactgcacaa taaaccagag atttatcgaa atctggaagg gttatccaaa atgcgaccat
    11881 aacagaatgc accaggtaat cacggcgacg ataatggcaa tcagcaccgc ggcggatccc
    11941 atatctttag cgcgtccgga aagctcatgg tattcagagc caattcggtc aaccactgct
    12001 tcgatggcgc tattgagaat ttccacaatc atcaccagca tcacggagct gataagcagc
    12061 acgcgggtaa ttgcgtccac atccagccag caggcgatga ccaccgccaa caataccgct
    12121 acgccttcct gacggaatgc cgcttcgttg atccatgcag cgcgtaaacc tttccaggaa
    12181 tagccagcag ctttgataat tcgggtgaat ccagtggtat tattggccat tgaaagaacc
    12241 tttttacatt atgagcgtca atatcagtgt accgttaaat ccgatgattc gggtttgcgt
    12301 aacgccgcgc gaaacatgag cggataccac agaatttccc atgactttct gctatccttg
    12361 ccgcgcattt gcattattaa ccagaggctt tacatcgttt atgtccggct ggccacgaat
    12421 ttactacaaa ttactgaatt taccattaag catcctggta aaaagcaagt ctattccggc
    12481 agatcctgcc ccggaactgg ggctggatac ttctcgtcca attatgtacg ttttaccgta
    12541 caactcgaaa gcagatttgc tgacgttacg cgcccagtgt ctggctcatg acttgcctga
    12601 cccgttagag ccgctggaaa tcgacggcac gctactgccg cgctatgtgt tcattcacgg
    12661 cgggccgcgt gtattcacct attacacgcc gaaagaagag tctattaagc tgttccacga
    12721 ctatctcgat ttgcaccgta gcaacccaaa tctggatgtg cagatggtgc cagtatcggt
    12781 gatgtttggt cgcgcgccgg ggcgtgaaaa aggcgaagta aacccgccgc tgcgtatgct
    12841 taacggcgta cagaaatttt tcgccgtact gtggctcggt cgcgacagtt ttgtgcgttt
    12901 ctcgccgtca gtttcgctgc gccgtatggc ggatgaacac ggcacggata aaactatcgc
    12961 acagaaactg gcgcgcgtgg cgcgtatgca ctttgcccgt caacgtctgg ctgctgtggg
    13021 cccacgtctg cctgctcgtc aggatctgtt taataagctg ctcgcctccc gcgccattgc
    13081 caaagcggta gaagatgaag cgcgcagcaa aaaaatctcc catgaaaaag cgcagcagaa
    13141 cgcgattgcg ctgatggaag agattgcggc gaatttctct tacgagatga tccgcctgac
    13201 tgaccgcatt ctgggcttca cctggaaccg actttatcag ggcatcaacg tccataacgc
    13261 cgagcgcgtt cgccagctgg cccacgacgg tcatgagctg gtgtatgtgc cttgccaccg
    13321 cagtcacatg gactacctgc tactttctta cgtgctgtac caccaggggc tggtgccgcc
    13381 gcatatcgcc gccgggatca acctgaactt ctggccggcc gggccgattt tccgccgtct
    13441 gggggcgttc tttattcgcc gtacttttaa aggcaataaa ctttattcca ccgttttccg
    13501 tgagtatctc ggcgaactgt tcagccgtgg ttattccgtc gagtacttcg tggaaggcgg
    13561 tcgttcccgc acggggcgtt tgctggatcc gaaaaccggt acgctgtcga tgaccattca
    13621 ggcgatgctg cgtggcggca cgcgtccgat tacgctgatt ccgatctata tcggttatga
    13681 gcacgtcatg gaagtgggta cttacgccaa agaactgcgc ggcgcgacga aagagaaaga
    13741 gagcctgccg cagatgctgc gcggtttaag caagctgcgt aatctcggtc agggttacgt
    13801 caacttcggt gaaccaatgc cgttgatgac ctaccttaac cagcacgtac cagactggcg
    13861 tgaatctatc gatcccatcg aagcggtgcg tccggcctgg ttaacgccga cggtcaataa
    13921 tattgctgcc gatctgatgg tacgcattaa caacgcaggc gcggcaaacg ccatgaacct
    13981 gtgctgtact gcgctactgg catcacgtca gcgctcactc acccgcgagc agttaaccga
    14041 gcaactcaac tgctacctgg atctgatgcg caacgtacct tactccacgg actctaccgt
    14101 tccttcagcc agcgccagcg agcttatcga tcacgcgctg caaatgaaca agtttgaagt
    14161 cgagaaagac actatcggcg acatcatcat tctgccacgc gagcaagcgg tgctgatgac
    14221 ctactatcgc aacaacattg cgcatatgtt ggtgctgcct tcgctgatgg cggcaattgt
    14281 cacccagcat cgccacatct cccgcgacgt attgatggag cacgtcaatg tgctttaccc
    14341 aatgctgaaa gcggagctgt tcctgcgctg ggatcgcgac gagttgccgg acgttattga
    14401 tgcgctggca aatgagatgc aacgtcaggg gctgattacc ctgcaagatg atgagttgca
    14461 tatcaacccg gcgcattctc gcaccctaca gctgctggcc gcaggcgcgc gcgaaacgct
    14521 gcaacgttat gccatcacct tctggttgtt gagtgccaac ccgtcgatca accgcggtac
    14581 gctggagaaa gagagccgca ccgtcgcgca acgtctctcc gtgctgcacg gcatcaacgc
    14641 gccggagttc ttcgacaagg cggtgttcag ttctctggtg ctgacgctgc gtgatgaagg
    14701 gtatatcagc gatagcggcg acgccgaacc ggcagaaacg atgaaggttt atcagttgct
    14761 ggcggagttg attacatcag acgtgcgttt gacgattgag agtgcgacgc agggcgaagg
    14821 gtaatcagag agaattgccg gatgcggcga aaacgcctta tccggccttc cataatctgc
    14881 aaattcaata aattgcgatg tgttgtgtag gcctgagaag cgccgcgcat caggcaaccc
    14941 agaagaaagc cggatgatca tccggctttt ttacatcatc agaaatgcca gtaactcatt
    15001 gccagcccta aaaatagtac cagaccaaca tagttattat tcataaatgc tttaaagcag
    15061 gcttcacgct cgcggttggc aatcagtttt tgttgataaa caaacagcgc gccagccacc
    15121 acaattgacc agtaatatcc ccagcctaag ccatttaact caccgatgat cgccatcagt
    15181 gccagtacgc caatctgcaa aataccaata atcaatttat cgtattggcc gaacaggatt
    15241 gccgtggatt taatgccaat cttcacatca tcatcgcggt caaccatcgc atactgcgtg
    15301 tcgtaagcca ccgcccagag aatattggcg aggaacatta accagcaact caatggcacc
    15361 gactcactca cagcggcaaa agccattgga atcgaccagc caaacgccgc gcccagcacc
    15421 acttgcggga gatgggtata ccgcttcata aacgggtaca cccacgccaa cgccagagcg
    15481 gcaatcgaca acagaatggt catcgtattc agcgtcagta ccagtaaaaa cgaaatcagt
    15541 accagcacta caaacagtgc gcgcgcctct ttctctgtta ccgcgccgct gggaagtggt
    15601 cggttcgccg tgcgcttaac atgaccatca aactttcggt cagcataatc attcaccaca
    15661 catccagcag cgcgcatcag ccagacaccc gcgacaaata ccgccaggat ccagagctga
    15721 ggaacgcccg gtgtcgccac ccacaacgcc cataatgttg gccagagcag cagtaacgcg
    15781 ccaattggct tatccgtacg cattaagcga tgaaacgcca gcagcttatt ctgcgtcaga
    15841 ctccactcca tatttttttc ctcttagtac aacggtgacg ccggtaaaaa cagttctgtt
    15901 agcaacagcg gtttaccgct taatcgcagg cgggaacgtc gcccccacag tccggcatca
    15961 cggcctatct caataaagtc ccgggttaat gtcgatgatg tgaacagata gcgtcctaac
    16021 ggcgttttac ccaatttttg taacgccagc tccggcccgc ttaacgttga cacaggaacg
    16081 acggtacgac cggcaagcca cggttcacca tcggcacata acaaaatttc acgtaaccag
    16141 taacgagact ctttcggcag cagcggcagt tcttcgggga tttcattctg ctcgacaaac
    16201 ccttcgcgga tcatcgtcac gcttaccgtt tttccctgct gttcaaaacg ttttgtcatg
    16261 gaatcctcca gcaacagcca gtcgagcagt tgcggatcca gggcagggat ctctttaaaa
    16321 tagcgcagcg cacgcagttg cgttaacgcg gggtgtgaca tgccgaactc tccgttacat
    16381 aacgtaaagg cattgtatcg cagaaaagtg tttacgggag atgtaaagca aattaagtga
    16441 tctaatgcgc aacaaaaacg caacaatcgc atgaagtggt aaaccgctgt tgaaccttac
    16501 gctttgccga tgcccgtgct ggcgagggca accgtagggg catcaccgcc catgatgcca
    16561 ggaacggtga tgttttcctt tacttaaata cctatattct ttatacgagt agctcgccaa
    16621 ctcgcagtaa aaattgggaa aagcgcatat ttaccatgag atttggagct aaaaagtgtt
    16681 tcctgagtaa gattaatagg caacatctta tgtctggatt tatagataca cgtggaattc
    16741 caattggtat cttttgtagg attcaacata tcatgtaagc gctgggagct taccaccata
    16801 actggcccat catcggcaga ggagaacagg ataaagatat tatcctttcg tgttaattca
    16861 ttcgtgttaa aggttcttaa attatcttca atttctataa atagaggtga aacatcatca
    16921 ctacgaatcc actctttata aagataccag gcatttgctt tgatcatatc atccgttgat
    16981 cgta
//
LOCUS       DAZUDJ010000087        16648 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.087, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000087 DAZUDJ010000000
VERSION     DAZUDJ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16648
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.087"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..254
                     /gene="ypdI"
                     /locus_tag="ACHY1N_004172"
     CDS             <1..254
                     /gene="ypdI"
                     /locus_tag="ACHY1N_004172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="colanic acid biosynthesis lipoprotein YpdI"
                     /protein_id="HFS4046379.1"
                     /translation="SLFLLVSIMACNVFAFSISGGVSERSYKETEKTSAMTTTHSTKL
                     QPSQAILFKMREDAPPLNLTEEITPTYPTKANYLIHPVR"
     gene            complement(331..573)
                     /gene="yfdY"
                     /locus_tag="ACHY1N_004173"
     CDS             complement(331..573)
                     /gene="yfdY"
                     /locus_tag="ACHY1N_004173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HFS4046380.1"
                     /translation="MIYLWMFLALCIVCVSGYIGQVLNVVSAVSSFFGMVILAALIYY
                     FTMWLTGGNELVTGIFMFLAPACGLMIRFMVGYGRR"
     gene            926..1846
                     /gene="lpxP"
                     /locus_tag="ACHY1N_004174"
     CDS             926..1846
                     /gene="lpxP"
                     /locus_tag="ACHY1N_004174"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311285.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008951 - palmitoleoyl
                     [acyl-carrier-protein]-dependent acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009409 - response to cold [Evidence IEA];
                     GO_process: GO:0036104 - Kdo2-lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HFS4046381.1"
                     /translation="MFPQCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRI
                     GAMARPFLKRRESIARKNLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDS
                     RVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGRKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKADYSGYRLFITPEMEGYPTDENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPVGESSLYI"
     gene            2202..2273
                     /gene="ypdK"
                     /locus_tag="ACHY1N_004175"
     CDS             2202..2273
                     /gene="ypdK"
                     /locus_tag="ACHY1N_004175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HFS4046382.1"
                     /translation="MKYFFMGISFMVIVWAGTFALMI"
     gene            complement(2338..3576)
                     /gene="alaC"
                     /locus_tag="ACHY1N_004176"
     CDS             complement(2338..3576)
                     /gene="alaC"
                     /locus_tag="ACHY1N_004176"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HFS4046383.1"
                     /translation="MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVEIDPESEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     TFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKA
                     MFRADGLLPASSKHIHENAE"
     gene            3953..5650
                     /gene="ypdA"
                     /locus_tag="ACHY1N_004177"
     CDS             3953..5650
                     /gene="ypdA"
                     /locus_tag="ACHY1N_004177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     YpdA"
                     /protein_id="HFS4046384.1"
                     /translation="MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKE
                     LLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRY
                     LIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
                     PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLP
                     LFRHVNSESLRKVCEIIRDDIHADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQ
                     AMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAV
                     GLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTAR
                     QLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNC
                     CIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERV
                     EANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL"
     gene            5665..6399
                     /gene="ypdB"
                     /locus_tag="ACHY1N_004178"
     CDS             5665..6399
                     /gene="ypdB"
                     /locus_tag="ACHY1N_004178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator YpdB"
                     /protein_id="HFS4046385.1"
                     /translation="MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQH
                     NRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKP
                     YQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEA
                     HEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYI
                     LRLKDLDFEVPVSRSKVKEFRQLMHL"
     gene            6412..7269
                     /gene="ypdC"
                     /locus_tag="ACHY1N_004179"
     CDS             6412..7269
                     /gene="ypdC"
                     /locus_tag="ACHY1N_004179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4046386.1"
                     /translation="MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSL
                     CIDFPRLDIVLRGEYGNLLEAKQQRMVEGEMLFIPARAANLPINNKPVMLLSLVFAPT
                     WLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
                     LHLCRNVVNMPPGNSQPRGDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLF
                     AQHGTMRFIEYVRWVRMAKARMILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTP
                     GEYSARFQG"
     gene            complement(7272..9767)
                     /gene="ptsP"
                     /locus_tag="ACHY1N_004180"
     CDS             complement(7272..9767)
                     /gene="ptsP"
                     /locus_tag="ACHY1N_004180"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFS4046387.1"
                     /translation="MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEVTFINHRQNAKA
                     DAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSVQPTQAELTA
                     HPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRAIPASVQDSTRLEHSLA
                     TLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRRLMTEQHQGLGAAIISNMEQ
                     VCAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNNLVLEKPTILVAEDLTPSQ
                     FLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCG
                     VLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPG
                     AFANGAEGVGLFRTEMLYMDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKS
                     IPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHSLDQI
                     LWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMT
                     QYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTTAHQRGKWVGICGELGGESRYLPLL
                     LGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFTPEED
                     VRPLLALENIFVDRDFSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVG
                     FGVAIPHTKSQWIRHSSISIARLAKPIDWQSEMGEVELVIMLTLGANEGMNHVKVFSQ
                     LARKLVNKNFRQSLFAAQDAQSILTLLETELTF"
     gene            complement(9792..10829)
                     /gene="ypdE"
                     /locus_tag="ACHY1N_004181"
     CDS             complement(9792..10829)
                     /gene="ypdE"
                     /locus_tag="ACHY1N_004181"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFS4046388.1"
                     /translation="MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGS
                     VLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTR
                     EECKIPGLLDGDRQGNDVSAMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRV
                     MGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAI
                     VLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWIETVAAEIGVPLQAD
                     MFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMEQLLSALIQRLT
                     RETVVQLTDFR"
     gene            complement(10829..11914)
                     /gene="ypdF"
                     /locus_tag="ACHY1N_004182"
     CDS             complement(10829..11914)
                     /gene="ypdF"
                     /locus_tag="ACHY1N_004182"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFS4046389.1"
                     /translation="MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISR
                     ESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSW
                     ETAHRWKSELNAKLVSATPDVLRQIKTPEEVEIIRLACGIADRGAEHIRRFIQAGMSE
                     REIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQ
                     GYCSDMTRTLLVNGEGVSAESHPLFDVYQIVLQAQLAAISAIRPGVRCQQVDDAARQV
                     ITEAGFSHYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRI
                     EDVVLVTPQGAEVLYAMPKTVLLTGEA"
     gene            complement(11929..13176)
                     /gene="fryC"
                     /locus_tag="ACHY1N_004183"
     CDS             complement(11929..13176)
                     /gene="fryC"
                     /locus_tag="ACHY1N_004183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFS4046390.1"
                     /translation="MAIKKRSATVVPGASGAAAAVKNPQASKSSFWGELPQHVMSGIS
                     RMVPTLIMGGVILAFSQLIAYSWLKIPAEIGIMDALNSGKFSGFDLSLLKFAWLSQSF
                     GGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPV
                     PSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITP
                     FGGWINGGIRTVLTAAGEKGALMYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLP
                     VTARSIAIVIPPIGLGLATIIDRRLTGKRLFNAQLYPQGKTAMFLAFMGISEGAIPFA
                     LESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAVI
                     TALMVVFLRLMMFRKGKLLIDSL"
     gene            complement(13198..13524)
                     /gene="fryB"
                     /locus_tag="ACHY1N_004184"
     CDS             complement(13198..13524)
                     /gene="fryB"
                     /locus_tag="ACHY1N_004184"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFS4046391.1"
                     /translation="MSKKLIALCACPMGLAHTFMAAQALEEAAVEAGYEVKIETQGAD
                     GIQNRLTAQDIAEATIIIHSVAVTPEDNERFESRDVYEITLQDAIKNAVGIIKEIEEM
                     IASEQQ"
     gene            complement(13743..14708)
                     /gene="glk"
                     /locus_tag="ACHY1N_004185"
     CDS             complement(13743..14708)
                     /gene="glk"
                     /locus_tag="ACHY1N_004185"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005536 - D-glucose binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HFS4046392.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     IRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
                     VDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDI
                     TERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASG
                     FRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            14912..16168
                     /gene="yfeO"
                     /locus_tag="ACHY1N_004186"
     CDS             14912..16168
                     /gene="yfeO"
                     /locus_tag="ACHY1N_004186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HFS4046393.1"
                     /translation="MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQR
                     LPGTLGIAQDSPFWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPG
                     LIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALF
                     GTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQM
                     EMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMNQMKNPVLVLGIGGFILGILGVIGG
                     PVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVA
                     LGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVML
                     PAWLLLAGKPMMMVNRPKQQPPHDNV"
     gene            16283..16609
                     /gene="ypeC"
                     /locus_tag="ACHY1N_004187"
     CDS             16283..16609
                     /gene="ypeC"
                     /locus_tag="ACHY1N_004187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein YpeC"
                     /protein_id="HFS4046394.1"
                     /translation="MFRSLFLAAALMAFTPLAANAGEITLLPSIKLQIGDRDHYGNYW
                     DGGHWRDRDYWHRNYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGKGR
                     GHGHRH"
BASE COUNT         4012 a         4452 c         4185 g         3999 t
ORIGIN      
        1 tcagcttatt tttattggtc tctattatgg catgcaatgt ttttgcattt tccatttctg
       61 gtggtgtaag tgagaggagc tataaagaga ctgaaaaaac atcagcgatg acgaccacac
      121 actctacaaa acttcagcca tcacaggcga ttttgtttaa gatgagagaa gatgcgccac
      181 cattaaacct cacagaagaa atcacgccta cttatccgac aaaggcgaat tatcttattc
      241 atcctgtgcg atagcgtctg tcacatggca ggtgaacaat catgtctgat gctgatgtga
      301 acacctgccc aaatgagcca tcctgaccca ctatcgcctg ccatacccca ccataaagcg
      361 aatcatcaag ccacaagccg gggcaagaaa cataaatatc cccgtcacta gttcattacc
      421 gccagttaac cacatggtga agtaataaat gagtgcagcg aggatcacca tgccgaagaa
      481 agaagagacc gccgatacca cgttcagtac ctgaccgatg tagccgctta cgcagacaat
      541 acacagggcg agaaacatcc ataaataaat catagctcaa cctcctgccg cgctaaaaaa
      601 cctgtaactt cagtcacttt aatagtaaga caatccttaa cctctggcaa tttttgctaa
      661 gcatcaatga aaacagcatg ttaaatgcaa gactgttgtg tacggaaaaa tatttacttt
      721 gcacgattaa taatcagtag ctgaaagcag tcagcgagtg ataaagtaca gataccgcat
      781 tcatgctcct cgtggttatg tcctgactag tctttacact ctttacagga accattgtcg
      841 tacatgatgg cccaaccaat tgagtgtacc gctgtcgaca tggaatcttc tgcgatacaa
      901 caattcgtat ctacagaagg taactatgtt tccacaatgc aaattttccc gcgagtttct
      961 acatcctcgc tactggctca catggtttgg gcttggtgta ctctggcttt gggtacagct
     1021 tccttatcct gttctctgct ttctcggcac gcgtattggc gcaatggcgc gaccattcct
     1081 gaaacgtcgt gaatctatcg cccgtaaaaa cctggaactt tgtttcccgc agcattctgc
     1141 ggaagaacgc gagaagatga ttgccgaaaa ctttcgttca ctcggcatgg cgctggtaga
     1201 aaccggcatg gcatggttct ggcccgacag tcgcgtacgt aaatggtttg atgttgaagg
     1261 gttggataac cttaaacgcg cacaaatgca aaatcgcggc gtaatggttg tcggcgtcca
     1321 ttttatgtcg ctggaactgg gcggccgcgt gatgggactg tgccaaccaa tgatggctac
     1381 ctatcgtcca cataataatc agctgatgga atgggtgcag acccgtgggc gcatgcgctc
     1441 taacaaagcg atgatcggca gaaataatct gcgcggcatt gtcggtgcac tgaagaaagg
     1501 tgaagcggta tggtttgctc ccgatcagga ttatggtcgt aaaggcagct ccttcgcgcc
     1561 gttctttgcg gtggaaaatg tcgccacaac caatggcacc tatgttctct cccgtctctc
     1621 tggcgcagcc atgttgaccg taacgatggt aagaaaagcg gattacagcg gatatcgttt
     1681 gttcatcacc ccagagatgg aaggctaccc gacagatgaa aatcaagccg ctgcctatat
     1741 gaacaagatt atcgagaaag agatcatgcg cgcaccggag cagtacctct ggatccaccg
     1801 tcgctttaaa acgcgcccgg tgggagaatc gtcgttgtac atttaacaaa ctgctcttac
     1861 tctttccctc ctcaaatcgg ccataataac cttatggttt ttatggcttt tttcttaagg
     1921 ttttttcctt cgctgaatat ctaattatta ccgtcagaaa ttaaactgtc gccgatatga
     1981 gacacttgta agttactaaa agtaaataag aaaatgtctc ttgtctcgtt tcagttttag
     2041 gcgtacatta gcgccgtctc gagcagttta gctcagaatt ctggggtgat gcccacggta
     2101 aaatacaggg cttttaaggt cgctttgccc ggtgtcaact cactgtatca ggtgtaatga
     2161 agtcattcag gcgtaacagt aattacgcgg agagatgtaa agtgaaatat ttctttatgg
     2221 gcatttcttt tatggtcatc gtttgggccg gtacttttgc cctgatgatc taaaagcaaa
     2281 ctgtgcaatg aaaaacagga gccatcaggc tcctgtttgc atttctgacg acggtgttta
     2341 ttccgcgttt tcgtgaatat gtttgctgct ggcgggtagt aaaccgtcgg cacggaacat
     2401 cgctttaatc ccacgaatcg cctgacgaat acggtcgcgg ttttcgatca gtgcaaagcg
     2461 aacatgcgta tcaccatagt cgccaaagcc aatccccggc gagacacaaa ccttcgcttc
     2521 gttaaggagc ttcttggcaa attccagcga tcccatggcc gcatatggtt ccgggatttt
     2581 cgcccagaca tacatcgaag ccttcggcat ttcaaccatc cagcccgctt catgcagccc
     2641 tttaaccaat acatcacggc ggcgtttgta ctgttcggca atgtcgcgca cgcactgttg
     2701 atcgccctcc agcgccgcaa tcgccgccac ctgcaacggc gtaaaggtgc cgtaatcgtg
     2761 atagctttta atacgagcca gggcgctgac cagcgttttg ttgccaacca taaagccgat
     2821 acgccagccc gccatgttgt agcttttcga cagcgtaaag aactcgactg ccacatcgcg
     2881 tgcacccggt acctgcatga ttgacggcgc tttccagcca tcgtagacga tatcggcata
     2941 ggccaggtcg tggaccacca gcacatcgta gcgtttcgcc agcgccacaa ccttttcgaa
     3001 gaactccagc tccacgcatt gcgcggttgg attcgacggg aagccgagga tcatcatctt
     3061 cggtttcgga taactttcac gaatggcgcg ctccagttcg ttgaagaaat cgacaccttc
     3121 caccagcggc actgagcgta cctgcgcccc ggcaatcacc gcgccataaa tatggatcgg
     3181 gtaacttgga ttcggcacca gcaccgtgtc accatgatcc agcgtcgcca gcatcagatg
     3241 cgccaggccc tctttcgaac caatagtgac gatggcttct gattccgggt cgatttcaac
     3301 gtcgtagcga tcctgatacc agcgggaaat ggcgcgacgt aaccgcggaa tgccgcgtga
     3361 agtggagtaa ccatgcgtgt ccgggcgctg ggccacagta cataattttt cgacgatatg
     3421 cggcggagtc gcaccgtccg ggttacccat gctgaaatcg ataatatctt cgccgcgccg
     3481 acgcgcagcc attttcagtt cagcggtgat gttaaaaacg tagggcggga gacgatcaat
     3541 gcgcgtaaag cgacgttcag ggcgagtgtc agccataatt tcctcagatt aacgttagcg
     3601 cccggaccgt ccgagcgacg ctgccacaat ggtggctgtt ttgaaaatag cctgattaat
     3661 ttctgtctgt ccagcgtttt agaacatttt tatcaatggc tttaaatgag gaactccact
     3721 tcaaaaacag gaaatttttc tacgctaaca agaaaattac caccaatttt attaacatta
     3781 taatttcaat aaatttacca gccagaagtg cattatcaag agatacattg ctaatacacc
     3841 atttatcttt caatcccctt ttaaatttat ggtttttcct caaaaacggc ctgctggtca
     3901 tcagccttca ggttacctat catagaggtt taatccttat tcagagtcac ccgtgcacga
     3961 aatattcaac atgctgctgg cggtcttcga tcgggcagcg ttaatgctta tctgcctgtt
     4021 ctttctcatc cgtatccgcc tgtttcgcga actgttgcac aagtcggcgc actccccaaa
     4081 agaattgctc gccgttaccg ccattttctc gctgttcgcc ctgttcagca cctggtccgg
     4141 cgttcccgta gaaggctcgc tggtgaacgt acgtattatc gcggtgatgt ccggcgggat
     4201 tctgtttggc ccgtgggtag gcatcattac cggcgtgatt gcgggtattc accggtattt
     4261 aattgatatc ggcggcgtga cggcgatccc ctgctttatc accagcattc tggcgggttg
     4321 tatatcaggc tggataaacc tgaaaatccc caaagcacag cgctggcgcg tcggtattct
     4381 cggcggcatg ttgtgtgaga cgttgaccat gattctggta attgtctggg caccaactac
     4441 cgcgttgggg atcgatatcg tctctaaaat cggcattcca atgatcctcg gtagcgtctg
     4501 tatcggcttt attgtgcttc tggtgcaaag cgttgagggc gaaaaagagg ccagcgccgc
     4561 gcggcaggcc aagctggcgc tggatatcgc caacaaaacg ctacctctgt ttcgccatgt
     4621 caatagcgag tcattacgca aagtttgtga aattattcgc gatgacattc acgccgatgc
     4681 ggtggcgatt accaataccg atcatgtgct ggcctatgtt ggcgtgggtg aacataacta
     4741 tcagaatggc gatgacttca ttagcccgac tacccgtcag gcgatgaatt acggaaaaat
     4801 catcattaaa aacaatgatg aagcccaccg cacaccagag attcattcca tgctggtgat
     4861 cccattgtgg gagaaaggcg ttgtgaccgg aacgctgaaa atttactact gccacgcgca
     4921 tcagatcacc tcgtcattac aggaaatggc ggtcggtctg tcgcaaatca tctccaccca
     4981 actggaggtt tcacgcgccg agcagctacg tgaaatggca aataaggcag agcttcgcgc
     5041 cctgcaaagc aaaattaatc cccatttcct gtttaacgct ttgaacgcta tttcatcatc
     5101 aatccgtctg aatccggata ctgctcgcca gctgatcttt aatctgtcgc gttatctgcg
     5161 ctataacatt gaattaaaag acgatgagca aatcgatatc aaaaaagagc tgtatcaaat
     5221 taaagactat attgccattg agcaggcccg ctttggcgac aagctgacgg ttatctatga
     5281 tattgatgaa gaggtgaatt gctgcattcc cagcctgctg atccagccgt tggtggagaa
     5341 tgccattgtc cacggtattc agccttgcaa aggtaaaggc gttgtcacca tcagcgttgc
     5401 agagtgcggc aatcgggtac gcattgcggt gcgggatacc gggcacggca tcgatccaaa
     5461 ggtgattgag cgggtcgaag cgaatgaaat gccgggcaat aaaattggcc tgctgaatgt
     5521 tcatcatcgc gtgaagttat tgtatggcga ggggctgcat atccgccgcc tggaaccagg
     5581 aacggaaatt gcgttttaca ttcctaacca acgcacccca gtcgcctcac aggctacgtt
     5641 attgctttga gccggagtga tattgtgaaa gtcatcattg ttgaagacga attcctggca
     5701 caacaggaac tgagctggct aattaaagag cacagccaga tggagattgt cggcaccttt
     5761 gacgacggtc tggacgtgtt gaagtttttg cagcataacc gcgtcgacgc catttttctg
     5821 gatatcaata ttccgtcgct ggatggcgtg ttgctggcgc aaaacatcag ccagttcgcc
     5881 cataaaccgt ttattgtgtt catcaccgcg tggaaagaac atgcggtaga agcgtttgaa
     5941 ctggaggcgt ttgactacat tctcaaaccg tatcaggagt cacgtattac cgggatgctg
     6001 caaaaactgg aagcggcctg gcaacaacag cagaccagca gtacgcctgc cgcgacggta
     6061 acgcgtgaga atgacaccat taatctggtg aaagatgagc gaataatcgt cacgccaatt
     6121 aacgatatct attacgccga agcgcacgag aaaatgacct ttgtctatac gcggcgtgaa
     6181 tcctacgtaa tgccgatgaa cattaccgaa ttttgcagca aactgccgcc gtcgcatttt
     6241 ttccgctgcc atcgctcatt ttgtgtcaat ctgaacaaaa tacgcgaaat cgaaccgtgg
     6301 tttaataaca cctacattct gcgactgaaa gatctggatt ttgaagtgcc ggtcagccgc
     6361 agcaaagtga aagaatttcg ccagttaatg catctttaat cgggaacttt catgaaagca
     6421 ccaggcttgc ccgccgatca acaatttttc gccgatctgt tcagcggcct ggtgcttaac
     6481 ccgcaactac tggggcgcgt ctggtttgcc agccagcctg cctcgttacc ggtgggcagt
     6541 ttatgtattg attttccccg tctggatatc gtgctgcgcg gcgaatacgg caacctgctg
     6601 gaagcaaagc agcagcgaat ggtggaagga gaaatgctgt ttattccggc acgcgcggct
     6661 aatttaccga tcaacaacaa accggtgatg ctgttaagcc tggtgttcgc accgacctgg
     6721 cttgggttat cgttttacga tagccgcacc acgtcgttgt tgcatcctgc tcgccagatc
     6781 cagcttccca gcctgcaacg cggtgaaggt gaagcgatgc ttaccgccct cacccatctt
     6841 agccgttcgc cgctggagca gaatatcatt cagccactgg tgttaagttt gctgcatctt
     6901 tgccgtaacg tggtgaatat gccgccgggc aattcgcagc cgcgcggcga ttttctctat
     6961 cacagcattt gtaactgggt tcaggataat tatgcccagc cgctcacccg cgagagcgtg
     7021 gcgcagtttt ttaatatcac gcccaatcat ctgtcaaaac tgtttgctca gcatggaacg
     7081 atgcgtttta tcgagtatgt gcgttgggtg cgaatggcga aggcgaggat gattttgcag
     7141 aaatatcatc tgtcaattca tgaagtggca cagcgttgcg gttttccgga tagcgactat
     7201 ttttgtcgcg ttttccggcg tcagtttggt ctgacgccgg gagagtacag cgcccgtttt
     7261 cagggctaac gtcagaaggt taattctgtt tccagcagcg tcaggatact ttgtgcatct
     7321 tgcgcggcaa acaacgactg gcggaagttt ttattcacca gtttacgcgc cagctgcgag
     7381 aagactttca catgattcat cccttcgtta gcacccagcg tcagcatgat caccagttcg
     7441 acttcgccca tttctgactg ccagtcaatc ggtttcgcca gccgggcaat gctgatactg
     7501 gaatgacgga tccactgaga tttggtgtgc gggatcgcta cgccaaaacc aacgccggtg
     7561 gtaacaatct cttcccgctg ccagacatct tcttccagct caaacggatg ttcagtgcgc
     7621 ccgttaacgc cgaggttgcc gcacaggaac tggatcgcct gctctttatt gctaaaatcc
     7681 cgatcaacaa agatattctc cagcgccagc agtgggcgaa cgtcttcttc cggcgtaaag
     7741 gcggtgagta acgcttcaat ttcctgcgca ctgcggcatt cacatgcctg acgcgccagt
     7801 tcccgacacg cctcgctatc cagttgacga agctggcttt tcaccgccgg aatacgcggg
     7861 ctactcatac tcagctcatc caggcccagc ccaagcagta gcggcagata acggctttca
     7921 ccgcccagtt caccgcaaat gcctacccat ttgccccgct gatgcgcagt ggtaacaatc
     7981 tgctgcaaca tgcgcaggaa cgatggcgta atcgggttat acagcggcga tacgcgcggg
     8041 ttattacgat cgaccgcata cagatactgg gtcatatcgt tagaaccgat actgaagaaa
     8101 tcgacctcat cgcagaagtg gtcgatgatg taacacaccg acggcacttc caccatgata
     8161 cccagagtaa tcgtctctgc atgacgcagg ccatcgcgct taagctcaac gatcgctttt
     8221 tggatctcgc ccttcaccca taagatctga tcgaggctgt gaaccatcgg gatcatcaac
     8281 tgggcgttgc caaaactggc agcgcgcaaa atcgcccgta gttgagtgcg gaacaggcca
     8341 gcaaattccg ggtaaatacg taccgcgcga tagccgagga acgggttctc ttcctgggga
     8401 atattcagat aaggaatgct tttatcgcct ccgatgtcca ttgtgcggaa gataatcggc
     8461 ttgtcgcccg ctgccagtag cacctgctgg taggcttcaa attgctcctg ctcgtccggc
     8521 gcgctgtcac gatccatata cagcatttcg gtacggaaca gcccgacgcc ttccgcgccg
     8581 ttggcaaacg cgcctggtgc ttccagagcg gtgccaatat tcgccgcgat atcaatacgc
     8641 ttgttatcac gggaataggc cagctgcgcg gcagcctgcg cctgttgttt ttggcgttta
     8701 tccgccagcg tctgcgcaac ctgataataa ccgctcaccg cgtcattcgg gttaatcgcc
     8761 agcacgccgc actgggcgtc aagcaccgcc ggttgcccgg cataacgggc aatcgcatcc
     8821 agcggcaggc cgctcagtac cgggatcgcc gaggcgcggg ccagaatcag ggtatgcgag
     8881 gtgcgcccgg ttttctccag aatcatgccc gcaagatttt tcaaatcaag gctcaaaaac
     8941 tggcttgggg ttaaatcttc agccaccaga atggtcggtt tttccagcac cagattgttg
     9001 cgcggcttca gttccggcca ggtgatatgc agcaactgtt cgctaatatc gcgaatgtcg
     9061 ctaacacgtt cgcgcagata atcgctggca gaagcagaaa gcttggcgca aacctgctcc
     9121 atattgctga tgatcgccgc ccccagtccc tgatgctgtt ctgtcatcag gcgacggata
     9181 ttgcctgcaa attcatcatc ctgaatcagc gacaaatggg cgctgaggat agttttgctt
     9241 tcgccgtcac gctcacgcaa ttgctggttc agttgctcgg caagcgttgc caggctgtgc
     9301 tccagccggg tggaatcttg cacactggcg gggattgccc gataactgtc gaggctgtcg
     9361 ctttgtaaca gggtcagcgt acccacgccg acgccgcttg ccagcacatt gccgtacagt
     9421 aaatccgggt taaggcggct taatgaacgc ggcagcggat gcgccgtcag ttctgcctgc
     9481 gtaggctgga cgctgtcgct gtcgataaag cgcacctgga tgtactcttc cagcacgcgc
     9541 cgcgcctgct cttcatcgct gccgctaatg ttcaggctgc aactgtcatt aaatagggtg
     9601 ccggtgccaa tcagcgccag cgaacttttc gcatcggcct ttgcgttctg gcgatggtta
     9661 ataaaggtga cttcactttg ccactggctg cactgttctt taagttccca cgccggacga
     9721 gcatgcagac cgttaggcaa aggacagaga aattgaatcg ttaacataac cgctccgggt
     9781 taatcaggag atcatctgaa atccgtcagt tgaacaaccg tctcacgggt aagacgttga
     9841 ataagggcag ataaaagttg ctccatctgc aaaatgtcgc ggcaatcggc aatcgatgcc
     9901 gcgcaatgtc cgtggcgggt ggcaggcccc attaccactg tgggtacgcc agtaccggtt
     9961 aagtgcaccg ctccgccgtc cgtgccgccg ttgctgaaca tatctgcctg caacggtacg
    10021 ccaatttcag ccgccacggt ttcgatccag gcggtaagtt ttggcggcgc aatcagtgac
    10081 ttgtcgctta acaccagcat cgggccgtta ccaatctggc gatggttagc cgcgccataa
    10141 tcaaagtttt tcgcccagca ggcggtatcc agcacaatgg cgacgtccgg cgacaccgcg
    10201 cgggtagcgg tttgcccacc gcgtaatccc acctcttcgc tggaacttgc caccagccac
    10261 acctccgcag gcagttcggc atcgtgcagc tcacgtagta acgtcaccag cagatagcaa
    10321 ccgaggcgat catcaaaggc tttccccatc acccgctggt gagggagaac ctgaaaagtt
    10381 gtatcaaagg tgacgcgatc gcctggacga attcccgcct gcatcacttc gtcatacgag
    10441 cgcgcaccaa tgtccacgcg catggcgctg acgtcattcc cctgccggtc gccgtcaagc
    10501 aggcctggaa ttttgcactc ttcacgggtg gtgatgcgca ccggctgcag ctggcgggca
    10561 gccatgcgca cgttgccaac cggcagcaca tcaattgccc cttcgcggga gatgctacgc
    10621 accataaatc ccacttcgtc catatgggcg cagatcatca ccttcggacc tgtcgattca
    10681 ttgaggcgga tcagcaccga tcccagacca tcaaatcgca cttctttttg caggcgatcc
    10741 gcttcttcca gcaggatctg ccgcacttcc tgttccgagg aggcgatcgc atctgcctcg
    10801 ctcaacgctt ttaatagcga taaatccatt atgcctctcc cgtgagcaac actgttttcg
    10861 gcatggcgta gagcacttct gcgccttgcg gggtaaccag cacaacatct tcgatgcgca
    10921 cgcccccttg ccctggcaaa taaatccccg gctccacggt cagtaacatg cctggctgta
    10981 gcgtcgtggt gtcccgcggt gaaaaacgcg gatcttcatg aacttcaatg ccgatagcat
    11041 gaccggtgtt atgaccgaaa tagtggctaa aacctgcctc ggtaatcact tggcgcgcgg
    11101 catcgtcaac ctgctggcag cgcacgccgg ggcgaattgc agagattgcc gcgagctgtg
    11161 cctgcaggac aatctgatag acgtcaaaca gcgggtgaga ttcggcgctc accccttcgc
    11221 cattcaccag caaggtgcgc gtcatatcag agcagtagcc ctgatacagc gcaccaaaat
    11281 cgagagtgac aaactcgccc gctgcaacaa tcttgtcgct ggctttgccg tgcggcagcg
    11341 ccccgcgcca gccgctggcg acaatggtgt caaaagaggc tttttctgcg ccctgctggc
    11401 gcataaacca ctccagttca gcggctatct cgcgctcgct catccccgcc tgaataaagc
    11461 ggcgaatatg ctccgctccg cgatcggcaa tcccacaggc gaggcggatt atctccacct
    11521 cctctggcgt tttgatttgc cgcagcacat ccggcgtggc gctaaccagt ttcgcattga
    11581 gttcagactt ccagcggtgc gcggtttccc aactcacctg ctggccttca aaaccgagcg
    11641 tttgcaactg ctcatcggca atgatttgat tgacgatagt ggtaagcgtg ttcgtcgcgt
    11701 caagcaaatg cagctggtag ccttgcgcac gggcttccac ctcaacgtaa tagcgcgaat
    11761 ccaccagaat gtgcgcactt tcacggctaa taaccacata gcctgatccg gtggagatcc
    11821 ccagatgcgg ctgtttgttc tgccgtgagg agagaagcac tgcatccagt tgttgcgcct
    11881 taagccagtc gcgcagcgaa gcgagtaatg tcatctggat tttccttctt acaggctatc
    11941 gattaacaat ttgcctttac ggaacatcat cagacgcagg aacaccacca tcagcgcagt
    12001 tatgactgcc cccagcgcga tccccgccat atagacgccc aggttagtga ccagcggcca
    12061 tgcccagata gcggactctg ggaaccattg cactgcgccc agccagacag cggcggttga
    12121 gccgacaata gcgccgacca tatacgacgg aatggcggtg atggggcttt ccagcgcaaa
    12181 cggaatcgca ccctcactga tccccataaa cgccaggaac atggcggtct taccctgcgg
    12241 ataaagttga gcgttgaaca ggcgtttgcc ggttaaacga cggtcgataa tggtcgccag
    12301 ccccagacca atcggcggaa taacgatagc gatagaacgc gcggtaaccg gtaatacgtg
    12361 gtcggtggta aagctgaagg caacgaaacc tgccgctttg ttgattgggc caccaaggtc
    12421 gattgcggtc gccgcggcaa tccccattgc atacatcagc gcgcccttct cacctgcggc
    12481 agtcagcacg gtacggatac cgccgttgat ccagccacca aatggggtga tgacatagta
    12541 catcgccagc atgacaaaaa tggcggaaag aatcggtagc aaaaatgtgg ttttgaacgc
    12601 taacaggaaa tctggtaact ggattttctg gttcatccat ttcacaaggt aaccagcaac
    12661 gatagatata atcagcgcac caatgaaggt ggacggcacc ggcgaagagg tcgcccattg
    12721 catagtgctg ggatcgaagt tcagcagttg cgtcggctgg gtagacatca agccgccgat
    12781 aaaaccagcc gggaacgcca gtttgccgcc gatagagttc gccacaaaag cggcaaacat
    12841 cggaatagca aagccaaaca acacgccgcc gaaggactgc gacagccagg caaatttcag
    12901 taaggagagg tcgaaaccgg agaatttccc gctattaaga gcatccatga tgccgatctc
    12961 agcaggaatt ttaagccagc tataagcaat cagctggctg aaagcgagga tcacaccgcc
    13021 cataattaag gtcggcacca tgcgtgaaat ccctgacatc acatgctgcg ggagttcacc
    13081 ccagaagctg cttttagagg cctgcggatt cttaactgcc gctgccgcac cggatgcgcc
    13141 aggcacaacg gttgcactgc gttttttaat ggccataaca attatccctg tcgaatatta
    13201 ctgttgttca gaggcaatca tctcttcgat ttctttgatg atgcctacag cgtttttaat
    13261 tgcgtcctgc aaagtgattt cataaacgtc gcgtgattcg aaacgttcgt tatcttccgg
    13321 ggtaactgcc acggaatgga tgatgatggt cgcttcggcg atatcctgcg ccgtcaggcg
    13381 attctggatg ccgtccgcgc cctgggtttc aattttcact tcataaccgg cttctaccgc
    13441 cgcttcttcc agcgcctgag cggccataaa agtgtgagcc aggcccatcg ggcaggcaca
    13501 taaggcaatc agtttcttac tcatcgttaa ttcctcgttc agtgatagtt gacgagtgaa
    13561 attatgaacg tgcaaaacaa atcgccgtta ccagacaaat aatgcattta ctggagaatt
    13621 aatcccgctg tatggaagtg tgacgcaggt cggccttgtg aggggacaca aagaaaaatt
    13681 gaattaactg tatgatttaa aagattatcg ggagagttac ctcccgatat aacaggaagg
    13741 atttacagaa tgtgacctaa ggtctggcgt aaatgtgcac cggaaccgag aagacccgga
    13801 ttgtcatgga cgatgagata caccggaata tcatggacat attctttaaa gcgcccttta
    13861 tcttcaaatg cggcacggaa accagaggct ttgaagaact caaggaagcg cggcacgata
    13921 ccgcccgcaa taaacacgcc gccaaatgtc ccgagattga gcgccagatt gccgccaaaa
    13981 cggcccataa tgacgcaaaa cagcgacaac gcgcggcggc aatcggtgca gctgtcagcc
    14041 agcgcgcgtt cggtaatatc ttttggcttg agattttctg gcaggcggtt gtcagctttc
    14101 acaattgcgc gatacaaatt caccagccca gggccagaaa gcacgcgctc cgccgaaaca
    14161 tgaccaattt ccgcacgcaa tatttcgagg ataatggcct cttcttcact attcggcgca
    14221 aaatcaacgt gaccgccttc gcccggcaag cttacccaac gcttatcgac atggaccaga
    14281 tgcgcaaccc caagccctgt tccggcaccg taaaccgcaa taggtttacc ttctaccggt
    14341 tctgcgccac caaactgaat cagatgctct tttttcagca tcgggatcgc catcgataca
    14401 gcggtaaaat cgttaataat ttccagatgg ctaaaaccga gattcttttt catttcggca
    14461 attgagaacg cccaggtatg gttggtcatt gccacccagt caccggtaat cgggcaagcg
    14521 atggcaatac agccgtcttt cacctcgacc ttatgttctt caagataaac gcgaatgacc
    14581 gcttcgaggc tggggtaatc aagccctgaa taggtcttag cctgcgagat ttcaccactg
    14641 gcaatatcac acagagcaag acgtgcgttg gtgccgccca catcaccgac taatgcatac
    14701 tttgtcattc ttcaactgct ccgctaaagt caaaataatt ctttctcaca ctgtaaatac
    14761 ctgggggcat aacaacaacg ccggaaaggc aggctccctg taaatatcga tctgggtcac
    14821 acaattactt tatcgtttca gcaccaattg cagcgatgcc tttttgcaag ctgggcaaac
    14881 taagtatctg accccgcata aggaatagaa catgctccat ccgcgagcca gaaccatgtt
    14941 gttattatcg ctccccgccg tggcaattgg gattgcgtcc agtcttattc tgattgtggt
    15001 gatgaaaatc gcctcggtat tacagaattt gctctggcaa cgactgccgg gaactctggg
    15061 gatagcccag gattcacctt tctggatcat cggtgtatta acgctaacag gtattgcggt
    15121 ggggttggtt atccgcttca gccagggtca tgccggacca gaccccgcct gtgaaccgct
    15181 gatcggcgca ccggttccac cttccgcgct accaggactt atcgtagcat taattctcgg
    15241 tcttgctggc ggcgtcagcc tggggccaga acatccgatc atgaccgtca atatcgccct
    15301 tgccgtcgcc attggcgctc gtctgttacc gcgcgtcaac cgaatggagt ggactatttt
    15361 agcctctgcc ggaaccatcg gcgcgctgtt tggtacacct gttgcggcgg cgttgatatt
    15421 ttcgcaaacc ttaaatggca gtagtgaagt tccgctatgg gatcgtcttt ttgcgccatt
    15481 aatggcggca gcagctggtg cacttactac cggattattt ttccatcccc atttttcact
    15541 gcccattgcg cattacggac agatggaaat gaccgatatt ctcagcggtg caattgtcgc
    15601 ggcgattgcc atcgcagcag gaatggtcgc cgtatggtgc ttaccacggt tgcacgcgat
    15661 gatgaatcaa atgaaaaatc cggtgctcgt gctgggtatt ggcggattta ttctcggtat
    15721 tctgggggtt attggtggac cagtttcgct gtttaaaggg ctggatgaga tgcagcagat
    15781 ggtggcaaat caggctttca gcaccagcga ttactttttg ctggcggtaa ttaaacttgc
    15841 cgccctggtc gttgctgccg ccagtggctt tcgcggtggg cgaatcttcc cggcagtgtt
    15901 tgtcggcgtg gcattagggt tgatgctgca tgagcacgta cccgccgtac cagcggcaat
    15961 aaccgtttct tgcgctattc tcggcatcgt gctggtggta acacgcgatg gctggttaag
    16021 tctttttatg gcggcggtcg ttgtacccaa taccacattg ctaccgctgc tctgtatcgt
    16081 catgctcccg gcatggctgt tattagcagg taagccgatg atgatggtca atcgtccgaa
    16141 gcaacagcca ccccacgata acgtttagca aaaaatgctc tcctttatga tttaagagtt
    16201 atggcgatga tacggggctt tacctccccg taatattgcg ttaacaggcc gctgacggct
    16261 tcgatcgtga aggagaataa caatgttcag gtcactgttt ctggcggccg ccctgatggc
    16321 atttaccccg cttgcagcaa acgcaggtga aatcacccta ctgccatcaa tcaaattaca
    16381 aattggcgat cgcgatcatt acggtaatta ctgggacggt ggtcactggc gcgaccgtga
    16441 ctactggcat cgcaattatg agtggcgtaa aaaccgctgg tggcgtcatg ataatggcta
    16501 tcatcgtggc tgggataagc gtaaagcgta tgagcgtggc tatcgtgaag gctggcgcga
    16561 tcgtgacgat catcgcggaa aaggccgcgg acatggacac cgccattaaa cacattcgcc
    16621 aatggaacac aatgcctgat gcgacgct
//
LOCUS       DAZUDJ010000088        16371 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.088, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000088 DAZUDJ010000000
VERSION     DAZUDJ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16371
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.088"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..510)
                     /locus_tag="ACHY1N_004188"
     CDS             complement(<1..510)
                     /locus_tag="ACHY1N_004188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HFS4046395.1"
                     /translation="MTFKHYDVVRAASPSDLAEKLTHKLKEGWQPFGSPVAITPYTLM
                     QAIAAEGDVTTPVAVTGNEGKAVAVSATSDPEYYFVVVLAGQSNGMSYGEGLPLPETY
                     DRPDPRIKQLARRSTVTPGGAACKYNDIIPADHCLHDVQDMSRLNHPKADLSKGQYGT
                     VGQGLHIAKK"
     gene            complement(1010..1279)
                     /gene="stxB1a"
                     /locus_tag="ACHY1N_004189"
     CDS             complement(1010..1279)
                     /gene="stxB1a"
                     /locus_tag="ACHY1N_004189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Shiga toxin Stx1a subunit B"
                     /protein_id="HFS4046396.1"
                     /translation="MKKTLLIAASLSFFSASALATPDCVTGKVEYTKYNDDDTFTVKV
                     GDKELFTNRWNLQSLLLSAQITGMTVTIKTNACHNGGGFSEVIFR"
     gene            complement(1289..2236)
                     /gene="stxA1a"
                     /locus_tag="ACHY1N_004190"
     CDS             complement(1289..2236)
                     /gene="stxA1a"
                     /locus_tag="ACHY1N_004190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Shiga toxin Stx1a subunit A"
                     /protein_id="HFS4046397.1"
                     /translation="MKIIIFRVLTFFFVIFSVNVVAKEFTLDFSTAKTYVDSLNVIRS
                     AIGTPLQTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEGRFNNLRLIVERNNLYVTG
                     FVNRTNNVFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTS
                     YLDLMSHSGTSLTQSVARAMLRFVTVTAEALRFRQIQRGFRTTLDDLSGRSYVMTAED
                     VDLTLNWGRLSSVLPDYHGQDSVRVGRISFGSINAILGSVALILNCHHHASRVARMAS
                     DEFPSMCPADGRVRGITHNKILWDSSTLGAILMRRTISS"
     gene            complement(2743..3177)
                     /locus_tag="ACHY1N_004191"
     CDS             complement(2743..3177)
                     /locus_tag="ACHY1N_004191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0060567 - negative regulation of
                     termination of DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator Q family protein"
                     /protein_id="HFS4046398.1"
                     /translation="MRDIRQVLERWGAWAANNHEDVTWSPIAAGFKGLIPEKVKSRPQ
                     CCDDDAMIICGCMARLNRNNSDLHDLLVDYYVLGETFMALARKHGCSDTCIGKRLHKA
                     EGIVEGMLMMLGVRLEMDRYVERELPGGRTSVFYQRKNSLRS"
     gene            complement(3170..3364)
                     /locus_tag="ACHY1N_004192"
     CDS             complement(3170..3364)
                     /locus_tag="ACHY1N_004192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage NinH family protein"
                     /protein_id="HFS4046399.1"
                     /translation="MTFTVKTIPDMLLEAYGNQTEVARILNCNRATVRKYIGDKEGKK
                     HAVVNGVLMVHRGWGKDTDA"
     gene            complement(3361..3966)
                     /locus_tag="ACHY1N_004193"
     CDS             complement(3361..3966)
                     /locus_tag="ACHY1N_004193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinG"
                     /protein_id="HFS4046400.1"
                     /translation="MAKPARRKCKICKEWFHPAFSNQWWCCPEHGTQLALERRSKERE
                     KAEKAAEKKRRREEQKQKDKLKIRKLALKPRSYWIKQAQQAVNAFIRERDRDLPCISC
                     GTLTSAQWDAGHYRTTAATPQLRFDERNIHKQCVVCNQHKSGNLVPYRVELINRIGQE
                     AVDEIESNHNRHRWTVEECRAIKAKYQQKLKDLRNSRSEAA"
     gene            complement(3966..4688)
                     /locus_tag="ACHY1N_004194"
     CDS             complement(3966..4688)
                     /locus_tag="ACHY1N_004194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFS4046401.1"
                     /translation="MNELINSNAIKMTSIEIAELVGSRHDKVKQSIERLAVRGVIRNP
                     PMVVFEKINNLGLLRGVEAYVFEGEQGKRDSIIVVAQLSPEFTARLVDRWRELEGATA
                     KIPQTFSEALRLAADLEDQKAELEKQLALAAPKVEFADRVGEASGILIGNFAKVVGIG
                     PNKLFAWMRDHKILIASGSRRNVPMQEYMDRGYFTVKETAVNTNHGIQISFTTKITGR
                     GQQWLTRKLLDNGMLKVTREAA"
     gene            complement(4763..5497)
                     /locus_tag="ACHY1N_004195"
     CDS             complement(4763..5497)
                     /locus_tag="ACHY1N_004195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor Ant"
                     /protein_id="HFS4046402.1"
                     /translation="MTTQISVETLSPITHNQIPVITTELLAQLYGTEPVRIRQNHHEN
                     KVRFVEGKHFFKVVGNDLKELRVALNYSQNLRVTLSNSQNLQPSLRGLQISPKARSLI
                     LWTERGAARHAKMLETDQAWDVLEKLEDCYFSQCEKNTGKQEKKLNGLSAKETDSLVW
                     LWDYANRSQALFRELYPALKLIQSGYSGICHDYGYEFSYIIGRARGVLINHTRDIDIY
                     EPDGPTNLLAWERLKNKELPPSLHRY"
     gene            complement(5772..5954)
                     /locus_tag="ACHY1N_004196"
     CDS             complement(5772..5954)
                     /locus_tag="ACHY1N_004196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016063117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NinE family protein"
                     /protein_id="HFS4046403.1"
                     /translation="MRRQRRSITDIICENCKYLPTKRSRNKRKPIPKESDVKTFNYTA
                     HLWDIRWLRHRARKTR"
     gene            complement(5951..6478)
                     /locus_tag="ACHY1N_004197"
     CDS             complement(5951..6478)
                     /locus_tag="ACHY1N_004197"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage N-6-adenine-methyltransferase"
                     /protein_id="HFS4046404.1"
                     /translation="MTIKSNTPAHDKDCWQTPLWLFDALDIEFGFWLDSAASDKNALC
                     AHWLTEADDALNSEWVSHGAIWNNPPYSNIRPWVEKAAEQCIQQRQTVVMLVPEDMSV
                     GWFSKALESVDEVRIITDGRINFIEPSTGLEKKGNSKGSMLLIWRPFISPRRMFTTVS
                     KAALMAIGQGVRRAA"
     gene            complement(6475..6921)
                     /locus_tag="ACHY1N_004198"
     CDS             complement(6475..6921)
                     /locus_tag="ACHY1N_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinB"
                     /protein_id="HFS4046405.1"
                     /translation="MKQTFLLRNEAIRNNAIDAILSLPIDDKSPHEVHVKEPKRSKAQ
                     NDRMWPMLNDVSRQVLWHGQRLAPEDWKDLFTALWLKTKKLEQRSVPGIDGGVVMLGV
                     RTSKMRKASMTELIEIMFWFGSERNVRWSDDSRREYEWSQRKGRAA"
     gene            complement(6878..7114)
                     /locus_tag="ACHY1N_004199"
     CDS             complement(6878..7114)
                     /locus_tag="ACHY1N_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lar family restriction alleviation protein"
                     /protein_id="HFS4046406.1"
                     /translation="MSDLSLTQPKLKECPFCGGNARLWVEAGINIDVWGYAECDLCEA
                     RGAWAPSVAAAAEKWNRRAGDEANLSASQRSNQK"
     gene            complement(7125..7340)
                     /locus_tag="ACHY1N_004200"
     CDS             complement(7125..7340)
                     /locus_tag="ACHY1N_004200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046407.1"
                     /translation="MSTIAELVRANFREELVRWYRYRSSSSLPLDELYEHSPAARRYP
                     RDRVLRRLFKLNNEFQRNRIIRSLDLK"
     gene            complement(7473..7751)
                     /locus_tag="ACHY1N_004201"
     CDS             complement(7473..7751)
                     /locus_tag="ACHY1N_004201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046408.1"
                     /translation="MNDSYRQFENWWSKDKSQFTGDDELKEFAWVIWQASRSAIELDI
                     DWPESNDDFWKDGEEGAYAMGYEDGRDKTVIAVMKAIRAAGIKEKNFD"
     gene            complement(7822..8112)
                     /locus_tag="ACHY1N_004202"
     CDS             complement(7822..8112)
                     /locus_tag="ACHY1N_004202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein ren"
                     /protein_id="HFS4046409.1"
                     /translation="MTGKEAIIHYLGTHKNFCAQDVSAVTGATVTSINQAAAKMARAG
                     ILVIDGKVWRTVYYRFATREEREGKMSTNLIFKECRQSAAMKRVLAVYGVKR"
     gene            complement(8109..8810)
                     /locus_tag="ACHY1N_004203"
     CDS             complement(8109..8810)
                     /locus_tag="ACHY1N_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein P"
                     /protein_id="HFS4046410.1"
                     /translation="MKNIAAQMVNFDREQMRRITNNMPEQYDEKPQVQQVAQIINGVF
                     SQLLATFPASLANRDQNELNEIRRQWVLAFRENGITSMEQVNAGMRVARRQNRPFLPS
                     PGQFVAWCREEASVIAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNL
                     YQNMRANALTDAELRRKAADELTCMTARINRGETIPEPVKQLPVMGGRPLNRVQALAK
                     IAEIKAKFGLKGVSV"
     gene            complement(8807..9745)
                     /locus_tag="ACHY1N_004204"
     CDS             complement(8807..9745)
                     /locus_tag="ACHY1N_004204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFS4046411.1"
                     /translation="MTNTAKILNFGRGNFAEQERNVADLDDGYARLSNMLIEAYSGAD
                     LTKRQFKVLLAILRKTYGWNKPMDRITDSQLSEITKLPVKRCNEAKLELVRMNIIKQQ
                     GGMFGPNKNISEWCIPQNEGGSPKMRDIPQNEGKSPKTRDKTSLKLGDCYPSKQGDTK
                     DTITKEKRKDYSSENSGESSDQPENDLSVVKPDAAIQSGSKWGTAEDLTAAEWMFDMV
                     KTIAPSARKPNFAGWANDIRLMRERDGRNHRDMCVLFRWACQDNFWSGNVLSPAKLRD
                     KWTQLEINRNKQQAGVTAGKPKLDLTNTDWIYGVDL"
     gene            complement(9778..10074)
                     /locus_tag="ACHY1N_004205"
     CDS             complement(9778..10074)
                     /locus_tag="ACHY1N_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CII family transcriptional regulator"
                     /protein_id="HFS4046412.1"
                     /translation="MEQTSYSKLSQREIDRAETDLLINLSTLTQRGLAKMIGCHESKI
                     SRTDWRFIASVLCAFGMASDISPISRAFKYALDEITKKKSPVAAGDSKQIDMQF"
     gene            complement(10213..10440)
                     /locus_tag="ACHY1N_004206"
     CDS             complement(10213..10440)
                     /locus_tag="ACHY1N_004206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4046413.1"
                     /translation="MQNLDEPIKGVGIPEVAKACGVSERAVYKWLKNGFLPKTEFFGK
                     TKYASKIEEISGGKYQASEMLEISKKNLLAA"
     gene            10519..11226
                     /locus_tag="ACHY1N_004207"
     CDS             10519..11226
                     /locus_tag="ACHY1N_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HFS4046414.1"
                     /translation="MVQNEKVRKEFAQRLAQACKEAGLDEHGRGMAIARALSLSSKGV
                     SKWFNAESLPRQEKMNALAKFLNVDVVWLQHGTSLNGANDEDTLSFVGKLKKGLVRVV
                     GEAILGVDGAIEMTEERDGWLKIYSDDPDAFGLRVKGDSMWPRIKSGEYVLIEPNTKV
                     FPGDEVFVRTVEGHNMIKVLGYDRDGEYQFTSINQDHRPITLPYHQVAKVEYVAGILK
                     QSRHLDDIEAREWLKSS"
     gene            11287..11628
                     /locus_tag="ACHY1N_004208"
     CDS             11287..11628
                     /locus_tag="ACHY1N_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3024 domain-containing protein"
                     /protein_id="HFS4046415.1"
                     /translation="MAFNDLEYQAVKKEVHQFIESIRPPEHIRNELDIVYSINDQTID
                     IGEQRPVWQGNPGETNILPSARIKYIRSLDRWKIYWMRKDMKWHQYSTELSLTDALEL
                     VRANPDCCFFG"
     gene            11696..12157
                     /locus_tag="ACHY1N_004209"
     CDS             11696..12157
                     /locus_tag="ACHY1N_004209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001221210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046416.1"
                     /translation="MRILGVRAAPKVTSFVVYCTNESALKCVDVIKIPSTLDTPEKLK
                     YVRNNILDILNLYNVELAAIRVTESNSDNLSIDRLYIEAVIQEAFSSSDVRKYYTIRK
                     SGMKSSLNLTEIEYKEILKSHRNINGIDNSGFTTETNEAVLAALSAEVRGC"
     gene            12151..13197
                     /locus_tag="ACHY1N_004210"
     CDS             12151..13197
                     /locus_tag="ACHY1N_004210"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase"
                     /protein_id="HFS4046417.1"
                     /translation="MLTPYKRADVEFEWISDLEEQGCFSKVYLAHDRHLAHDLVIKEI
                     EKKENTNHDDYFNEARLLYKHAHPNIVQVQYAAQCESNIYIAMPFYHNGSLNQLMKKN
                     NLTSREIIRYSIQFLSGLYHIHSKGLMHFDIKPNNIMISNRNEAMLSDFGLSQLVNEE
                     SRAAPEFGYHFHVPPEYFSLSTNDYNFTYDIYQAGLTIYRMCVGHDNFERERSAFSTI
                     EQLRESIINGCYPLKEYPPHIHKKLITIVNKCIHVDPNERYQSVLDVLNDLSAISDGV
                     LDWRLQMTKPTNGTCEWQKKSGDAILSIVFDAENSSTTGFRLYDDGRKRRATNLTISS
                     GCTPTKLYRLLKDN"
     gene            13200..13364
                     /locus_tag="ACHY1N_004211"
     CDS             13200..13364
                     /locus_tag="ACHY1N_004211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000745484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046418.1"
                     /translation="MKKREEVSKLPRRRDAALAVPYKKDEFISPSDDKKFSKAKSFTS
                     TSLKDKYFKI"
     gene            14168..14236
                     /locus_tag="ACHY1N_004212"
                     /pseudo
     CDS             14168..14236
                     /locus_tag="ACHY1N_004212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311021.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
     gene            14295..14765
                     /locus_tag="ACHY1N_004213"
     CDS             14295..14765
                     /locus_tag="ACHY1N_004213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046419.1"
                     /translation="MTKSWSVPFPESETEHDGMPVFWRFQATVEEDGIKIFALQYIAF
                     HQTEHYAWLVPAHWIVNFKPAPNQWLQEWKQRRNRYAIKKVAKNAERSFAFPTKKLAI
                     ESLLRRKKYHLMRIKQDLAVVSTLVDGMKNIDTSTPDIEYNFGHNQETENWVFY"
     gene            14915..15283
                     /locus_tag="ACHY1N_004214"
     CDS             14915..15283
                     /locus_tag="ACHY1N_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2528 family protein"
                     /protein_id="HFS4046420.1"
                     /translation="MSNIKKYIIDYDWKASIEIEIDHDVMTEEKLHQINNFWSDSEYR
                     LNKHGSVLNAVLIMLAQHALLIAISSDLNAYGVVCEFDWNDGNGQEGWPSMDGSEGIR
                     ITDIDTSGIFDSDDMTIKAA"
     gene            15356..15520
                     /locus_tag="ACHY1N_004215"
     CDS             15356..15520
                     /locus_tag="ACHY1N_004215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease FtsH-inhibitory lysogeny factor CIII"
                     /protein_id="HFS4046421.1"
                     /translation="MQYAIAGWPVAGCPSESLLERITRKLRDGWKRLIDIPNQPGVPK
                     NGSNTYGYPD"
     gene            15489..15632
                     /gene="kil"
                     /locus_tag="ACHY1N_004216"
     CDS             15489..15632
                     /gene="kil"
                     /locus_tag="ACHY1N_004216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309204.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitory peptide Kil"
                     /protein_id="HFS4046422.1"
                     /translation="MDQTLMAIQTKFTIATFIGDEKMFREAVDAYKKWILMLKLRSSK
                     SIH"
     gene            15708..16004
                     /locus_tag="ACHY1N_004217"
     CDS             15708..16004
                     /locus_tag="ACHY1N_004217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0060703 - deoxyribonuclease inhibitor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor Gam family protein"
                     /protein_id="HFS4046423.1"
                     /translation="MNAYYIQDRLEAQSWARHYQQIAREEKEAELADDMEKGLPQHLF
                     ESLCIDHLQRHGASKKAITRAFDDDVEFQERMAEHIRYMVETIAHHQVDIDSEV"
     gene            16010..>16371
                     /gene="bet"
                     /locus_tag="ACHY1N_004218"
     CDS             16010..>16371
                     /gene="bet"
                     /locus_tag="ACHY1N_004218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HFS4046424.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQF
                     IALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNE
                     SCTCRIYRKDRNHPICVT"
BASE COUNT         4364 a         3903 c         3583 g         4521 t
ORIGIN      
        1 ttttttggcg atatgcagcc cctgccccac ggtaccgtac tgcccttttg acaggtccgc
       61 tttcggatgg ttaagacggc tcatgtcctg cacatcatgc agacaatggt ccgccggaat
      121 gatgtcgtta tatttgcatg ctgcaccgcc cggtgtcacc gtactgcggc gcgccagctg
      181 cttaatacgc gggtccggac ggtcatatgt ctccggcagc ggaagacctt caccatacga
      241 catgccattt gactgccctg ccagaaccac aacaaagtaa tactccgggt cgctggtggc
      301 actgacagcc accgccttac cctcattacc ggtcaccgcc actggtgtgg tgacatcacc
      361 ttccgccgca atggcctgca tcagggtata aggggttatg gccaccggac taccaaacgg
      421 ctgccagccc tctttcagtt tgtgtgtcag cttttccgca aggtctgacg gcgacgccgc
      481 cctgacaaca tcataatgtt taaatgtcat tattcctccc ggccgggata gtgtattaaa
      541 tcagatatgg agtgggctgt agtccggaag cctgaatgac acacggggac tacagcccga
      601 aatacgaaaa aggccgcgca gttgcgcagc cttatgaatc ctggttaaaa tccgcacgat
      661 aaaaatgaca atgcaagtat ctcatgctgt tgcccgaacc cactcgggct tttttttgca
      721 tgtaaaaagg ctcctgcgat gaggagcctg gatatatgcc taatctctgt atacagcatg
      781 atgccgggtg cctcccggtg agttcggcct ggtgccacca aacccgcgta ttctcgctta
      841 cgatcatcaa agagatcata ccgttcacca gtcgcccctc cgcacagggg gattcaccat
      901 gcagaaattt tctaacacat ctattatcag accggcaaca actgactgaa ttgagatgta
      961 tttaacattt atgaatctcc gcctgctatt ttcactgagc tattctgagt caacgaaaaa
     1021 taacttcgct gaatccccct ccattatgac aggcattagt tttaatggtt acagtcatcc
     1081 ccgtaatttg cgcactgaga agaagagact gaagattcca tctgttggta aataattctt
     1141 tatcacccac tttaactgta aaggtatcgt catcattata ttttgtatac tccacctttc
     1201 cagttacaca atcaggcgtc gccagcgcac ttgctgaaaa aaatgaaagc gatgcagcta
     1261 ttaataatgt ttttttcatt ttaccccctc aactgctaat agttctgcgc atcagaattg
     1321 cccccagagt ggatgaatcc cacaatattt tattgtgcgt aatcccacgg actcttccat
     1381 ctgccggaca catagaagga aactcatcag atgccattct ggcaactcgc gatgcatgat
     1441 gatgacaatt cagtattaat gccacgcttc ccagaattgc attaatgctt ccaaaagaaa
     1501 ttcttcctac acgaacagag tcttgtccat gatagtcagg caggacgcta ctcaaccttc
     1561 cccagttcaa tgtaagatca acatcttcag cagtcattac ataagaacgc ccactgagat
     1621 catccagtgt tgtacgaaat cccctctgta tttgccgaaa acgtaaagct tcagctgtca
     1681 cagtaacaaa ccgtaacatc gctcttgcca cagactgcgt cagtgaggtt ccactatgcg
     1741 acattaaatc cagataagaa gtagtcaacg aatggcgatt tatctgcatc cccgtacgac
     1801 tgatccctgc aacacgctgt aacgtggtat agctactgtc accagacaat gtaaccgctg
     1861 ttgtacctgg aaaggtaaca tgtgaaaaat cagcaaagcg ataaaaaaca ttatttgtcc
     1921 tgttaacaaa tcctgtcaca tataaattat ttcgttcaac aataagccgt agattattaa
     1981 accgcccttc ctctggatct atccctctga catcaactgc aaacaaatta tcccctgtgc
     2041 cactatcaat catcagtaaa gacgtacctc ctgatgaaat agtctgtaat ggagtaccta
     2101 ttgcagagcg aatgacattc agcgaatcta catacgtctt tgcagtcgag aagtctaagg
     2161 taaattcctt cgccaccaca ttaactgaaa agataacaaa gaaaaaagtt agcactctaa
     2221 aaataattat tttcatatta cacaatactc cttgagcacc atacgataac tatattcttg
     2281 acatcctcca cgccctgaag gacggcgttt tacggcgcac cggataaacg taacaataac
     2341 gtaatgaaaa tgataatcat attcaaagag agctgcaacc ttaacatatc tggtcagatc
     2401 tcatgcgact acttgacgta cgtagataac aacatttatt gatacacagg atgttacgga
     2461 cataaaaaag ccagccactg ggggaggctg gcaaactcgt agagcaaaat gctgttacgc
     2521 aaacttcgtt acagggtcat cctgcaatac aaaaaataca caatatttag aaaactaata
     2581 gtgccatgtg caatttttaa gattttgtta ttaattgtgg tcgcaccttc ctttctgtgt
     2641 actttccgta tagctcacag gattctgggt acaaaaaaac ccgcgcatcg gcgggttaag
     2701 cagcgtggca atgtaaccac tcttatcatg atatgcagat ttttacgatc gtaaactatt
     2761 ttttcgctga taaaatacag aggttctccc tcccggcaat tcacgctcaa cataccgatc
     2821 catctcaagc ctcactccca gcatcatcag catgccttca acaatcccct ccgctttgtg
     2881 aaggcgttta cctatacagg tgtcagagca cccatgtttc cgtgccagcg ccatgaacgt
     2941 ctcccccaac acgtaataat caaccagcaa gtcatgcaga tcgctgttgt tcctgttaag
     3001 gcgagccata cacccgcata taatcatcgc gtcatcgtca caacactgtg gacgtgattt
     3061 tactttttcg gggatcagtc ccttaaatcc ggcagcaatg ggcgaccatg taacatcctc
     3121 atggttattt gccgcccatg ccccccagcg ctcaagaacc tgccggatat cacgcatcag
     3181 tatctttacc ccatccgcga tgaaccataa ggacgccatt gacgacggcg tgctttttcc
     3241 cttctttatc gccaatgtat tttctgactg tggcacgatt gcagttcagt attcgggcta
     3301 cctcggtctg atttccatat gcctcaagga gcatgtcagg aatggttttt actgtgaacg
     3361 tcatgcggcc tcacttctgc tgtttcgcag gtctttaagt ttctgctgat acttcgcctt
     3421 gatcgccctg cattcttcga cagtccagcg atggcggtta tggttcgatt cgatttcgtc
     3481 tactgcttcc tgcccgatgc ggttaatcag ttcgacgcga tacggaacga gatttccgct
     3541 tttgtgctgg ttgcacacca cgcattgctt gtgaatattg cgttcatcaa atcggagttg
     3601 aggtgtcgca gcagttgtcc ggtaatgtcc ggcatcccac tgagcagacg tgagcgttcc
     3661 gcacgagata catggtaagt cgcggtctct ttctctgatg aaggcgttta cggcttgttg
     3721 ggcttgttta atccagtaac tgcggggctt taaggcgagt tttcgaatct tcagtttatc
     3781 tttctgtttc tgctcctctc gtcgtcgttt cttctctgct gctttttccg ctttttcgcg
     3841 ttctttactt cgtcgttcga gtgctaattg agttccgtgt tccgggcagc accaccactg
     3901 atttgagaat gccgggtgaa accattcctt gcatattttg catttccttc gcgctggttt
     3961 agccattaag cagcctccct tgttactttc agcattccgt tatcgagcag ctttctggtc
     4021 agccactgtt gaccacgccc ggtgattttt gtggtgaacg atatctgtat tccgtgattt
     4081 gtattgaccg ctgtttcttt cactgtgaaa tagccacgat ccatatattc ctgcattggc
     4141 acattgcgcc gggagcctga agcaataagg attttgtgat cgcgcatcca cgcaaacagt
     4201 ttgtttggac caataccaac aacctttgca aagtttccaa tcaaaattcc gctggcctcg
     4261 ccaacgcgat cggcaaactc aactttaggt gctgcgagag caagctgttt ctccagttca
     4321 gccttctggt cttcaaggtc ggccgcaagg cgcaatgcct cagaaaaggt ttgtggtatt
     4381 ttcgcggttg ccccttcgag ttctcgccag cggtcaacaa ggcgagcggt gaattccggc
     4441 gacaactggg caacgacaat aatgctgtcg cgcttacctt gttcgccctc aaaaacgtaa
     4501 gcctctacgc cacgaagtaa tcctaagtta ttgatttttt cgaaaaccac cattggggga
     4561 tttcggatca cacctcgaac cgccagtcgt tcaatggatt gtttcacctt gtcatgacgg
     4621 cttcccacca actcagcgat ttcaatgctt gtcattttga tggcattgct atttatcagc
     4681 tcattcattg tcatgtcctc tcacattgaa aattcagcaa taaaaaaccc agccgaagct
     4741 gggtttgtta agttgtcaat tgtcagtagc gatgcagtga aggcggcaac tctttgttct
     4801 taagcctttc ccatgccaga aggttcgtcg gcccgtcagg ctcataaata tctatatccc
     4861 gcgtgtgatt aattaaaacg cccctcgccc tcccgatgat atacgagaac tcatagccgt
     4921 agtcgtggca tatgccggaa tagccagact gaatcagttt taatgcggga tacaactcac
     4981 ggaacaatgc ctgtgagcgg ttggcataat cccacagcca tacaaggctg tctgtttctt
     5041 ttgcggaaag cccgttgagc ttcttctctt gtttgccagt atttttctcg cactggctga
     5101 aatagcagtc ttccagtttt tctaacacat cccacgcctg atcagtttcg agcatttttg
     5161 cgtgacgggc tgcgcctcgt tctgtccaga gtatgaggga gcgggctttc ggggaaattt
     5221 gtaaccctct taaagatggt tgcaaatttt gtgagttact taaagtaacc cgcaaatttt
     5281 gtgagtagtt taaagctacc cgcaattctt taaggtcatt accaacaact ttgaaaaagt
     5341 gtttcccttc aacgaagcgt actttgttct catgatgatt ctggcgaata cgcaccggct
     5401 cagtgccgta aagctgcgcc aaaagttcgg tggtaataac aggaatctgg ttatgggtga
     5461 tcggggagag agtttcaaca gaaatttgag ttgtcataat gacgccctct ggtggtttct
     5521 taataactca ccaccgacga cgccaatcgt ctggtggtga actgtgcagg gttggcgtaa
     5581 ccgggaaacc gaccggcgcg gatctctccg cccccacaca gcccaccata attcagatgt
     5641 gcgcgtgcat acgacaataa aaaacacgct cgcggcgtgt atctgtcgcg gtctctatcc
     5701 aggacgccaa tcccgacgcc agattttgct ggcgcgtgag gaatatagcc ccgaataaat
     5761 catcgcgtca atcaccttgt tttcctcgca cgatgtctta gccaccggat atcccacagg
     5821 tgagccgtgt aattgaaggt ttttacgtca gattcttttg ggattggctt gcgtttattt
     5881 ctggagcgtt tcgttggaag gtatttgcag ttttcgcaga tgatgtcggt gatacttcgt
     5941 cgctgtcgcc tcatgccgcc ctcctgacgc cctgcccgat cgccatcaat gccgctttgg
     6001 atacagtagt aaacattcgt cgaggactga tgaacggtcg ccaaatcagc agcatggagc
     6061 ctttgctgtt tcccttcttc tccagccctg tcgatggttc gataaaatta atccgtccat
     6121 cagtgatgat gcgaacttcg tcaacactct ccagagcctt gctgaaccat ccgactgaca
     6181 tatcctctgg cacaagcata actaccgtct gtcgctgttg tatgcactgc tcagcggctt
     6241 tttccaccca cggcctgata ttgctgtacg gtgggttatt ccagattgca ccgtggctta
     6301 cccactcaga attgagcgcg tcgtcggcct cagttagcca gtgagcgcac agagcatttt
     6361 tgtcgctcgc tgccgaatcc agccagaatc caaactcaat atccagtgca tcaaaaagcc
     6421 aaagcggcgt ttgccagcag tccttgtcgt gtgctggcgt atttgatttg atagtcatgc
     6481 agccctacct tttcgttgtg accattcata ctctcgccgg gagtcatcac tccaccgcac
     6541 gttgcgctct gagccgaacc agaacatgat ttcgataagc tcagtcatgc tggccttccg
     6601 cattttgctg gtacgcacgc caagcatgac aacgccaccg tcgataccag gcacacttcg
     6661 ttgctccagt tttttggtct taagccacag ggcagtgaac aggtctttcc agtcttccgg
     6721 cgccagccgt tgaccatgcc atagcacctg acgcgaaaca tcgttcagca tcggccacat
     6781 gcggtcattc tgcgctttgc tgcgcttggg ttctttaacg tggacttcgt ggggtgactt
     6841 gtcgtcgatg ggtagtgaga gaatggcgtc tatggcgtta tttctgattg cttcgttgcg
     6901 aagcagaaag gtttgcttca tctcctgctc tccggttcca tttttcagcc gccgcagcaa
     6961 ctgatggtgc ccatgccccc ctggcttcac agaggtcaca ttctgcatag ccccacacat
     7021 caatatttat tccggcctca acccacagac gagcattacc gccgcaaaac ggacattctt
     7081 ttagctttgg ctgggttaat gataggtcgc tcatgctcac tccttcactt taaatccaga
     7141 ctccggataa ttctgttgcg ctgaaactca ttgttgagtt tgaacaaccg tcgaagaaca
     7201 cggtcacgcg gatagcgtcg tgcggcaggt gaatgctcat acaactcatc aagcggcaaa
     7261 ctggacgatg aacgataccg ataccaacgc accaactcct cacgaaaatt agccctgaca
     7321 agctcagcta tcgtactcat ttcttaaaac ctcctcaaac gcattctgac gcatttttca
     7381 ttctcgctgc ttattggcat gccttgcacg cgtttacctc gctacagagc gattgtgatg
     7441 ccttaaaagc gatttattga agtgatattt gcttaatcga aattcttttc tttgattcct
     7501 gcggccctga tggctttcat tactgcaatt accgttttgt cacgcccatc ctcataaccc
     7561 atcgcataag caccttcttc accatctttc caaaagtcgt cattcgattc gggccagtcg
     7621 atatccagtt caatagcaga gcgcgatgcc tgccatatca cccaggcaaa ctcttttaat
     7681 tcatcgtctc ccgtgaactg gcttttgtct tttgaccacc agttttcaaa ctgtcggtag
     7741 ctatcgttca cttccctctc ccccaaataa aaaggcctgc gattaccagc aggcctgtta
     7801 ttagctcagt gatgtagatg gtcatctttt aactccatat accgccaata cccgtttcat
     7861 cgctgcactc tggcgacact ccttaaaaat caggttcgtg ctcatctttc cttcccgttc
     7921 ttccctggta gcaaaccggt aatacaccgt tcgccagacc ttaccatcaa tgaccaggat
     7981 tcctgcccgc gccattttag ccgcagcctg atttatgctg gttacggttg cgcctgttac
     8041 cgcggaaacg tcctgtgcac agaagttctt atgcgtcccg aggtaatgaa taattgcctc
     8101 tttgcccgtc atacacttac tcctttcagt ccgaacttag ctttaatttc tgcgatcttc
     8161 gccagcgcct gaacacgatt tagaggtctg ccgcccatga caggaagttg ttttactggt
     8221 tcaggtatcg tctcaccacg gttaattcgt gctgtcatac aggtcagttc atcggcagcc
     8281 ttgcgccgta attccgcgtc agtcagcgca ttggcccgca tgttctggta caggttggta
     8341 accagccagt agtgcgcgtt tgatttccac ggataagact ctgcatccgg atacaggcca
     8401 cgcttccggc aatactcgta aaccatatca accagctcgc tgacgtttgg cagtccggcg
     8461 ataacggatg cttcttcccg gcaccatgca acaaactgcc cgggtgatgg aagaaatggt
     8521 cgattctgcc gacgggctac gcgcattcct gcgttaacct gttccatcga ggtgatcccg
     8581 ttttcccgga aagccagaac ccactggcgg cggatttcat tcagttcgtt ctggtcccgg
     8641 ttagccagac tcgccgggaa agttgccagt aactggctga acacaccgtt gatgatctgc
     8701 gctacctgtt gtacctgcgg cttttcgtcg tactgttccg gcatgttgtt ggtgatccga
     8761 cgcatctgct cacggtcaaa gttaaccatc tgtgcggcga tgtttttcat aaatccaccc
     8821 cgtaaatcca gtcagtgttt gtcaggtcga gttttggttt tccagctgtc acgccagcct
     8881 gttgcttgtt acggttgatt tcgagttggg tccacttgtc gcggagtttg gccggactta
     8941 gcacgttacc ggaccagaag ttgtcctggc atgcccagcg gaacagcacg cacatgtcgc
     9001 ggtggttacg tccgtcacgt tcacgcatca ggcggatatc gttagcccac cctgcaaaat
     9061 tcggttttct ggctgatggt gcgatggtct tcaccatgtc aaacatccac tctgcggcgg
     9121 tcaggtcttc tgctgttccc cacttgctgc cgctctgaat tgcagcatcc ggtttaacca
     9181 cagaaagatc gttttctggc tggtcagagg attcgccaga attctcggac gaataatctt
     9241 ttcttttttc ttttgtaata gtgtcttttg tgtccccctg ttttgaggga tagcaatccc
     9301 ctaatttgag ggatgtttta tccctcgttt taggggattt tccctcgttt tgagggatgt
     9361 ccctcatttt aggggaacct ccctcgtttt gagggatgca ccattctgag atgtttttat
     9421 ttggtccaaa catgccgcct tgctgcttga taatattcat tctgacgagt tctaacttgg
     9481 cttcattgca ccgtttgaca ggtaactttg taatctcgct aagttgagaa tcggtgattc
     9541 tgtccattgg tttattccac ccataggttt tacgcagaat ggcaagcagc actttaaact
     9601 gtcgcttggt cagatctgcg cctgaataag cctcaatcag catatttgat agtctggcgt
     9661 aaccatcatc gagatctgcc acattacgct cctgttcggc aaagttacct ctgccgaagt
     9721 tgagtatttt tgctgtattt gtcataatga ctcctgtgga ttgatccagt aattccctca
     9781 gaattgcata tcaatttgct tagagtcccc ggcggccacc ggggattttt tctttgtgat
     9841 ttcatcaagc gcatacttaa aagctctgct aatcggactg atgtctgatg ccatgccaaa
     9901 agcacacaag accgaagcta taaacctcca gtctgttctg cttatcttcg attcatgaca
     9961 gccaatcatc tttgccagac cgcgctgggt aagcgttgac aggttgatga gtaaatcagt
    10021 ttcagcgcga tcaatttctc gctgtgatag tttgctgtaa cttgtttgtt ccatttctta
    10081 agatttccaa tagtgaatag ctagttgaaa ggtatgcgtg gaaacgcata tggccttagt
    10141 tggtcagata tattgggact cgctttgtca gcgacgtagg acgaatgtcc attgtgaaaa
    10201 tagcggtgtt acttatgcag ccagaaggtt ctttttgctt atttcaagca tttcgcttgc
    10261 ttgatatttg ccaccagaaa tctcttcgat ttttgatgcg tatttagttt tcccaaaaaa
    10321 ctcagtctta gggaggaagc cgtttttgag ccacttatag acagcccttt cgctaactcc
    10381 acaagccttc gcaacttcag ggatgccgac acctttaatc ggctcatcaa gattttgcat
    10441 aggaatatcc tttttcgtac tttcagtacg tattatggtt gaactgaaag tttttgcaag
    10501 tgctttagta tcgtactcat ggttcagaat gaaaaagtgc gcaaagaatt cgcccagcgg
    10561 ctagcgcaag cctgtaaaga agctggtctt gatgaacatg gtaggggaat ggctatagcc
    10621 cgtgcccttt ctctttcgtc caaaggcgtt agcaaatggt ttaatgctga gtctttaccg
    10681 cgtcaggaaa aaatgaatgc gcttgcgaaa tttctaaacg ttgatgttgt ttggcttcag
    10741 cacggcactt cgttaaatgg agcgaatgat gaagatactc tttcatttgt tggcaaatta
    10801 aaaaaagggt tagtgcgcgt ggttggtgag gcaattcttg gtgttgatgg tgccatcgag
    10861 atgaccgaag agcgcgatgg gtggctcaaa atttatagcg atgatccaga tgcctttggt
    10921 cttcgtgtga aaggagacag catgtggccc agaataaaat caggagaata tgtactcatt
    10981 gagcctaaca ccaaagtatt cccgggtgat gaggtgtttg tcagaaccgt tgaaggacac
    11041 aacatgatta aggttcttgg ctatgacaga gatggagaat accaatttac aagcattaac
    11101 caggatcaca ggcctataac gttgccttat catcaagtag caaaggtgga gtatgtagct
    11161 ggtattctga agcaatctcg ccatctggat gacatcgagg caagggagtg gctgaaaagt
    11221 tcgtgacttc atcgtcacat agctggtaac cagtggcctg aagagacgtt tgggtaagga
    11281 ggatagatgg cgttcaatga ccttgaatat caagcagtaa aaaaagaagt tcaccaattc
    11341 attgaaagca taaggccgcc tgaacatatc cgcaatgaac tggatattgt ttatagcatc
    11401 aatgaccaaa cgatagatat cggcgaacag cgccccgtgt ggcagggcaa tccaggtgaa
    11461 acaaacatcc tgccatcagc aagaatcaag tacatacgtt ctctggatag atggaaaatc
    11521 tattggatgc ggaaggatat gaaatggcat cagtacagta ctgaactttc gctgactgat
    11581 gcgcttgagc ttgtgcgtgc taacccggat tgctgcttct tcggatgagt gaagagacgt
    11641 ttggatgatg gatggtcgca gagatgcggc ctgattctaa aataggatat aaaaaatgag
    11701 aatactaggt gttagagcgg cgcccaaagt tacatctttt gttgtatatt gcactaatga
    11761 gtctgcactc aaatgtgttg atgttattaa aataccttcg accttagaca caccagaaaa
    11821 attaaagtat gtgagaaata acatcctcga cattcttaat ttatataatg ttgaattagc
    11881 tgccatacgc gttactgaat caaactctga taatcttagc attgaccgcc tttatataga
    11941 agctgttatt caagaagcat tttcaagcag tgatgtaaga aaatattaca ctattagaaa
    12001 atctggcatg aaatcatcat tgaacctaac agagatcgag tataaagaaa tattgaagtc
    12061 acaccgcaat ataaatggaa tcgataattc tggttttaca actgaaacaa atgaagctgt
    12121 tttggctgca ctatctgcgg aggtaagggg atgctaactc catacaaaag agctgatgta
    12181 gaattcgaat ggattagtga tctagaagaa cagggttgtt tttcaaaagt atatctggct
    12241 catgacagac acctagctca tgacttggtg attaaagaaa tagaaaaaaa agaaaacact
    12301 aaccacgacg actactttaa tgaagcaagg cttctctata aacatgcaca tccaaatatt
    12361 gtgcaagttc agtatgctgc tcaatgtgag agcaatatct atatagccat gccattttat
    12421 cataatggtt cgctaaacca attaatgaaa aaaaataatc ttacaagcag ggagataata
    12481 cggtattcca ttcaattttt aagtggactt tatcatatac actcaaaagg tcttatgcat
    12541 tttgatataa aacctaataa cattatgata tcaaacagaa atgaggccat gctatctgac
    12601 tttggattat ctcagttagt caatgaggaa tcgagagctg cgcctgagtt tggatatcat
    12661 tttcatgtgc caccggaata tttttcttta tcaacaaatg attataattt cacatatgac
    12721 atatatcagg caggattaac catatataga atgtgtgttg gacatgataa ttttgaaaga
    12781 gaaagatctg catttagcac gattgaacaa ctcagagagt cgataattaa tggctgctat
    12841 ccattaaaag agtatcctcc ccatatacat aaaaaattaa taacaatagt gaacaaatgc
    12901 attcatgtag atccaaatga aagatatcaa tccgtactag atgtactaaa cgatctctca
    12961 gctataagtg atggcgttct tgactggcgt ctacagatga cgaaaccaac taacggcaca
    13021 tgcgaatggc aaaaaaagtc tggggacgct atactgtcta tagtttttga cgcagaaaat
    13081 tcgtctacta ctggttttcg tttatacgat gatgggcgga aaaggcgtgc tacgaactta
    13141 acaatatcct caggatgtac ccctacaaaa ctgtataggt tattaaagga taactgatca
    13201 tgaaaaagcg cgaggaagta agcaagctgc ctcgcagacg tgatgcagca ttagcggttc
    13261 cctacaaaaa agatgagttc ataagccctt ctgatgacaa aaaattttca aaggcgaaaa
    13321 gttttacatc tacatctcta aaagataaat actttaaaat ctagcccggc ctcagcgccg
    13381 ggttttcttt gcctcacgtt cgcccaccta aaaaacataa ccaattgtat ttattgatgt
    13441 aactcgctaa accatgcagt tatgatccct gccgcataac cttcatcagc cacattttca
    13501 aaaataaatt tccttatata tcagaatcat acttcgtaga gttaataaat caccaaaatt
    13561 cgtaccaata gttcttgata atgtcgaact attggttcat tatcatcgtc gtcagcagga
    13621 cgcattactc accagggcgg tgaatataca acgattcgaa tatgaatcta cggcgctgac
    13681 aaagcgcaat aaccaaagtg aactttgggg tgtggtgaag ggttcatgga cgggaatatg
    13741 tcgcacgtaa agcggcgagg cctgcgggac tattgccgaa ttgaagtagg ccgaaacagg
    13801 tcgaaatggg tctcccacct accacaccac caaagttcat caggaggtct atatgacacg
    13861 cagaactcag ttcaaaggca attcacgttc tcgtcgtcgt gagcgtttaa aggcaaaggc
    13921 attagctaac ggcgtactgg cccgcgaaga agcaataagt tcagaagtat tacaccgccc
    13981 tactctaagc agagcgcaga ttcaggctaa aggtactcac gaaacgcctg agcgcataga
    14041 agacgctaag ccaattaagt tcatggcaca ggacgtgatc tggcaacaga aagaatacag
    14101 acgcaatctg gagcgagcgg ccattgtgta cgcgaatgag tttggacata agcaaccaga
    14161 aactggtgta tgtcttccaa acgtagccat ttacgcggca ggctaccgga aatcaaaaca
    14221 actgacggcg aggtgacttg tgttggtcgc cagaaaatga aattaggcag caaaccactt
    14281 atttgaggtg agatatgaca aaatcatgga gcgtaccttt tcctgaatca gaaactgaac
    14341 atgatggaat gcctgttttc tggagattcc aggcgacagt tgaagaagat gggataaaaa
    14401 tattcgcact tcaatatata gcttttcatc agacagagca ttatgcatgg ttggttcctg
    14461 cgcattggat tgttaatttt aaaccagcac caaatcagtg gttacaggaa tggaaacaaa
    14521 ggagaaatag atatgcaatt aagaaagtag caaaaaatgc agaaagatct tttgcattcc
    14581 caacgaagaa acttgccatt gaaagtttat tgcgccggaa gaaataccat ttaatgagaa
    14641 tcaaacaaga tttggctgtt gtatcaactc ttgttgatgg tatgaagaat attgatacat
    14701 caacaccaga tattgaatat aactttggac acaaccaaga aacagaaaat tgggtatttt
    14761 attagtacga ataagcactg tgtattcatt ccaacgagtg aatacacgga gcaatgtcgc
    14821 tcgtaactaa acaggagccg acttgttctg attattggaa atcttctttg ccctccaatg
    14881 tgagggcgat ttttatctgt gaggatatga acagatgtca aacatcaaaa aatacatcat
    14941 tgattacgac tggaaagcat caatagaaat tgaaatcgac catgatgtaa tgacagagga
    15001 aaaacttcac cagattaata atttctggtc agactctgaa taccgactca ataaacacgg
    15061 ctctgtatta aatgctgtat taatcatgct ggcgcaacat gctctgctta tagcaatttc
    15121 aagcgactta aatgcatatg gtgttgtgtg tgagttcgac tggaatgatg gaaatggtca
    15181 ggaaggatgg ccttcaatgg atggtagcga aggaataaga attaccgata tcgatacatc
    15241 aggaatattt gattcagatg atatgactat caaggccgcc tgagtgcggc tttaccgcat
    15301 accaataacg cttcactcga ggcgtttttc gttatgtata aataaggagc acaccatgca
    15361 atatgccatt gcagggtggc ctgttgctgg ctgcccttcc gaatctttac ttgaacgaat
    15421 cacccgtaaa ttacgtgacg gatggaaacg ccttatcgac atacctaatc agccaggagt
    15481 cccaaagaat ggatcaaaca cttatggcta tccagactaa attcactatc gccactttta
    15541 ttggcgatga aaagatgttt cgtgaagctg tcgacgctta taaaaaatgg atattaatgc
    15601 tgaaactgag atcaagcaaa agcattcact aaccccattt cctgttttcc taatcagcct
    15661 ggcatttcgc gggcgatatt ttcacagcca ttttcaggag ttcagccatg aacgcttatt
    15721 acattcagga tcgtcttgag gctcagagct gggcgcgtca ctaccagcag atcgcccgtg
    15781 aagagaaaga ggcagaactg gcagacgaca tggaaaaagg cctgccccag cacctgtttg
    15841 aatcgctatg catcgatcat ttgcaacgcc acggggccag caaaaaagcc attacccgtg
    15901 cgtttgatga cgatgttgag tttcaggaac gcatggcaga acacatccgg tacatggttg
    15961 aaaccattgc tcaccaccag gttgatattg attcagaggt ataaaacgga tgagtacagc
    16021 actcgcaacg ctggctggga agctggctga acgtgtcggc atggattctg tcgacccaca
    16081 ggaactgatc accactcttc gccagacggc atttaaaggt gatgccagcg atgcgcagtt
    16141 catcgcattg ctgatcgtcg ccaaccagta cggtcttaat ccgtggacga aagaaattta
    16201 cgcctttcct gataagcaga acggcatcgt tccggtggtg ggcgttgatg gctggtcccg
    16261 tatcatcaat gaaaaccagc agtttgatgg catggacttt gagcaggaca atgaatcctg
    16321 cacatgccgg atttaccgca aagaccgcaa tcatccgatc tgcgttaccg a
//
LOCUS       DAZUDJ010000089        15958 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.089, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000089 DAZUDJ010000000
VERSION     DAZUDJ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15958
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.089"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..159
                     /locus_tag="ACHY1N_004219"
     CDS             <1..159
                     /locus_tag="ACHY1N_004219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HFS4046425.1"
                     /translation="ARIARVHQFGERDQVAPGIFTDYPVRELLGISQADERLIYNTVL
                     GRIAEAVR"
     gene            171..737
                     /locus_tag="ACHY1N_004220"
     CDS             171..737
                     /locus_tag="ACHY1N_004220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HFS4046426.1"
                     /translation="MRLLSNIIRTGIISEVDEKSWCVRVRSGELETGWLRWNTTRAGA
                     FNVWLPPSPGEQVVIACIGGNPETAMIIGSLWSDASPAPGKRLKEIVISAPDGAVFRY
                     DADAGALSASGMKTATLQASVSVKLDTPVVECTNLLRTATLDVTKGGKMSGNITHSGG
                     NFTSNGITVHTHKHGGVKGGSDSTGGPQ"
     gene            734..1084
                     /locus_tag="ACHY1N_004221"
     CDS             734..1084
                     /locus_tag="ACHY1N_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HFS4046427.1"
                     /translation="MTTRYTGMNPDGTGNLNDMEHLKQSVRDILTTPLASRVMRREYG
                     SLVPDLIDEPMNNTTRLQCMSAAVIALTRWEPRIALDAIDVVWKAGGRAGVTLSGTVM
                     QTMQNVELTITLRE"
     gene            1088..1984
                     /locus_tag="ACHY1N_004222"
     CDS             1088..1984
                     /locus_tag="ACHY1N_004222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HFS4046428.1"
                     /translation="MPAVDLSQLPEPAIIAEPDFEAILADTKAMMIAAYPAEQREAVS
                     AALELESEPLNVIAQTTAFREMLLRQRVNEGARACMLSHSAGTDLDNLAGNMNTKRLT
                     ITPATDTTDAVMESDTSLRLRAQRAYDGLSVAGPSGAYEYFARSASGLVRDARAISPS
                     PANVTVSILSTEGDGTATEALLNTVRAVLNAEDTRPVADRLTVQSASIVTWRLNAKLY
                     FYPGPESEPILAAAESSFRKWLAEQGLIGQDVALSAIAAALHVHGVQRVEIIEPTQNM
                     AISDIQAARCESFTISEGGRNE"
     gene            1977..2507
                     /locus_tag="ACHY1N_004223"
     CDS             1977..2507
                     /locus_tag="ACHY1N_004223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HFS4046429.1"
                     /translation="MSNSLLPPSASSFMRCAEAVGTRITDIPVDLNTLWSPDTCPVHL
                     LPYLAWAFSVDRWDRNWPEETKRQVIRDAWLIHRHKGTISALRRAIEPLGYLIRVSEW
                     WEFGGEPGTFTVEVGTLDSGVTEEMYLEMERLIADARPVSRHMTGLNIIQEIPGDIFA
                     AAATYDGEVITIYPDD"
     gene            2510..4807
                     /locus_tag="ACHY1N_004224"
     CDS             2510..4807
                     /locus_tag="ACHY1N_004224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001495276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019062 - virion attachment to host cell
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HFS4046430.1"
                     /translation="MSTTTRKFKTIITDTGAKKLAQAAAPDGNPVRLTHMAVGDGGGT
                     LPTPDSKQTRLVHEVWRHTVNRVILDATHQNRIIAELVIPPETGGFWIREIGVFDEHG
                     DLIAVGNTAESYKPTVAEGSGRAQTFRTILTVSSTATVALTVDNTMVMATVDYVDDKL
                     KEHEQSRRHPDASLTAKGFVQLSSATNSDSETLAATPKAVKAAHDLANGKYTAQDATT
                     ARKGIVQLSSATNSTSETLAATPKAVKAAYDLANGKYTAQDATTARKGIVQLSSATNS
                     TSETLAATPKAVKAVMDETNKKAPLNSPALTGTPTTPTAQQGTNNTQIANTAFVMAAI
                     AALVDSSPDALNTLNELAAALGNDPNFATTMTNALAGKQPKDATLTALAGLATAADRF
                     PYFTGNDVASLATLTEVGRDILAKSTVAAVIEYLGLQETVNKAGNAVQKTGDILSGGL
                     TFENDSILAWIRNTDWAKIGFKNDADSDTDSYMWFETGDNGNEYFKWRSRQSTTTKDL
                     MNLKWDALYVLVKALFSSEVKISTVNALRIFNSSFGAIFRRSEECLHIIPTRENEGEN
                     GDIGPLRPFTLNLRTGRISMGHGLDVTGDIFANRFAINSSTGMWIHMRDQNVILGRNA
                     VSTDGAQALLRQDHADRKFMIGGLGNKQFGIYMINNSRTANGTDGQAYMDNNGNWLCG
                     SQVIPGNYGNFDSRYVKDVRLGSQQYYGVNNWQTWNFQCPSGHVLSGINVQDTGSNSA
                     DNIAGVYYRPVQKYINGTWYNIASV"
     gene            4809..5336
                     /locus_tag="ACHY1N_004225"
     CDS             4809..5336
                     /locus_tag="ACHY1N_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001762409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0098004 - virus tail fiber assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HFS4046431.1"
                     /translation="MMHLKNIKAGNAKTLEQYELTKKHGVIWLYSEDEKNWYEEVKNF
                     QPDTIKIVYDKNQIIVAITRDASTLNPEGFSVVEVPDITSNRRADDSGKWMFKDGAVV
                     KRIYTTDEQQQQAESQKAALLSEAESVIQPLERAVRLNMATDEERARLESWERYSVLV
                     SRVDTANPEWPQKPE"
     gene            complement(5365..5898)
                     /locus_tag="ACHY1N_004226"
     CDS             complement(5365..5898)
                     /locus_tag="ACHY1N_004226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000972171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0098004 - virus tail fiber assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HFS4046432.1"
                     /translation="MMHLKNITAGNPKTKEQYQLTKQFNIKWLYSDDGKNWYEEQKNF
                     QPDTLKMVYGHNGVIICIEKDVSAINPEGASVVELPDITANRRADISGKWMFKDGVVV
                     KRTYTEEEQRQQAENEKQSLLQLVRDKTQLWDSQLRLGIISDEHKQKLTEWMLFAQKV
                     ESTDTSSLPVTFPEQPE"
     gene            complement(5901..6560)
                     /locus_tag="ACHY1N_004227"
     CDS             complement(5901..6560)
                     /locus_tag="ACHY1N_004227"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HFS4046433.1"
                     /translation="MEVIGTRGAMTIRVTTPSTSSGGGITNAQFTYINHGDAYAPGWR
                     RDYNTKNQQPAFALGQTGSTVGNDKAVGWNWNSGVYNANIGGASTLILHFNMNTGSCP
                     AVQFRVNYRNGGIFYRSARDGYGFEADWSEFYTTTRKPSAGDVGAYTQAECNSRFITG
                     IRLGGLSSVQTWNGPGWSDRSGYVVTGSVNGNRDELIDTTQARPIQYCINGTWYNAGS
                     I"
     gene            6926..7525
                     /locus_tag="ACHY1N_004228"
     CDS             6926..7525
                     /locus_tag="ACHY1N_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4046434.1"
                     /translation="MLIGYVRVSTNDQNTDLQRNALVCAGCEQIFEDKLSGTKTDRPG
                     LRRALKRLQKGDTLVVWKLDRLGRSMKHLISLVGELRERGINFRSLTDSIDTSSPMGR
                     FFFHVMGALAEMERELIVERTLAGLAAARARGRTGGRRPKLTKEQHEQIARLIKNGHD
                     RKQLAIIYGIGTSTIYRYHPVGDIQTEETTGQTQENENR"
     gene            complement(7554..8042)
                     /locus_tag="ACHY1N_004229"
     CDS             complement(7554..8042)
                     /locus_tag="ACHY1N_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001761054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4046435.1"
                     /translation="MMMIYGMFVFELRTLPHQQLQQNKSWRHVKNERVNRSASWQYIG
                     AGDDRIVLSGVLYPEITGGEVSLSLLATQAYTGRPWPLIDGVGQIYGIYVLTETNTTR
                     SEFDRYGKAKKIEFSLTLERCDEDLRERLQSSSFSDMLSGFKDKVTSSLNSAASSVKG
                     LF"
     gene            complement(8055..10862)
                     /locus_tag="ACHY1N_004230"
     CDS             complement(8055..10862)
                     /locus_tag="ACHY1N_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000853438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4046436.1"
                     /translation="MKTLDIRVAFSAVDRLTRPAENARRLMGRFGDSIQRTQGAIKNL
                     ERQARSFERARDAVSKADAGIVKARRQLNALNQLQRTGTVLSEKQQKLMQQLSTRLER
                     LNESRTREIQKMRELGGELKRHGISLTGSDNTIQQAIRRTEQYNNQLERERQALVRVT
                     RARERYSRAQETAGKLKTGGALATGAAAAGGYAAGRFLQPAIGFGKEMSRVQALTRID
                     QNSPQFKALREQALKLGSETQFTAGDAASGQAFLAMAGFTPQAIQAALPGVLSMATAG
                     GMDLGETADIGSNILTQFGLSADQMDRVGDTLTAAFTRTNTDLRALGETMKYAGPVAG
                     KLGISLEQAAAMAGVLANMGIRGSDAGTAMRASLARLASPPKAAAEALKELGVAVSDA
                     NGKMRPMEDVLADLYKATRKYGEVDRVSFFKDIAGEEAFTSFMALVDAAGDGSLPKLR
                     KELEGARGEAERTAKVMANNLDGDLKSLGSAWEGLRIRIADLIDGPLRSVTQWLTRVV
                     SRVTALAQAHPALTRQLLIAGGALLAMTATVGSLSLAIGVLAGPLAKLRLGFSLLTGS
                     MNAVRVLPALWGMVTGSVSLLGGAIGALFSPVGLIVAALAGAAILIWKYWDPIRAFFA
                     GVFSGIMERLTPLRETFERFGPVFDAIGSGISQVFNWFKSLLSPMESSKETLDKCTSA
                     GEIFGNVLGGALQLVLTPAKMLLDTLAWILEKLGVLPDEAERARKKIEDAQRAAILQD
                     KVALLQGDLAKINPPKPVENGNGTGGDKPKDNKPLTDSNTGTLRRLSKIADNTGKLVD
                     ETKKRIGPGDIVFKNLPRALAVRGEWQERKIAQVSKPAPAIKITPVVPAPLPPALVPV
                     VAASSRPVAEAIRSPVASTPAPSRNREPVASGFGGEIHVHLHNVVTQNPRELAKLVGE
                     MVRAEMERRARAGRGSFYDKD"
     gene            complement(10849..11004)
                     /locus_tag="ACHY1N_004231"
     CDS             complement(10849..11004)
                     /locus_tag="ACHY1N_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HFS4046437.1"
                     /translation="MCFEHIEDFVADIAAIFNWSPAEIFMMTPGEVVSWRERAALRSG
                     NADNEDS"
     gene            complement(11013..11378)
                     /locus_tag="ACHY1N_004232"
     CDS             complement(11013..11378)
                     /locus_tag="ACHY1N_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4046438.1"
                     /translation="MKETKNIDTENTVVADTVKETSEHGVKLTQPIERGGEKITYVEI
                     TGAIEQAGSLRNLSLSDVLNLKAESMFTLLSRVTSPRLDEVTIKKMASRDFIQLCVVA
                     VNFLSGADSGGKNEQATEA"
     gene            complement(11433..11945)
                     /locus_tag="ACHY1N_004233"
     CDS             complement(11433..11945)
                     /locus_tag="ACHY1N_004233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HFS4046439.1"
                     /translation="MAVPKHLRFFTLFVDGENEVGKVTSVTLPKLTRKTDSYRGGGMM
                     GAVSIDLGLDDSALDASFVMGGAVRELFLKYGGTIDGTLLRFAGEYYTDAESDLYEVE
                     MRGRVTEIDMGEAKQGEATSHTYAIKNTYYKLSVNDRPLWEIDLLNFIYRKDGKDIVP
                     DRIRSALGLG"
     gene            complement(11945..13129)
                     /locus_tag="ACHY1N_004234"
     CDS             complement(11945..13129)
                     /locus_tag="ACHY1N_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HFS4046440.1"
                     /translation="MSETRFHGARVTESTDLVTAINDVDSSVIGIVATADDADAELFP
                     LNKPTLLTRVNDVLGKCGTTGTLYRALKAIADQVSTKVIVVRVAEHKEEDGKTQDQLV
                     IGGSESDGSYTGMYALLVAEQDESIGYRPRILAAPELDTEAVTKSLCVIAGKLRAFVY
                     ASCHGCNTMAEAITYRQKFNEREVMLLWPDFIAYNPKSGKNETFPAPAYACGLRAYID
                     HEQGWHKSLSNVPVKNVLGMSRHVFWSLQAEDSDANSLNNKEITTIIRRNGFRFWGNR
                     TPETNAYIFEVYTRTAQVLADSIAEAQFETIDSPLTPANVKDVISAIRAKLDSLVTAG
                     KLIGASCWYDVVDNGTTNLRQGRVRIRYKYTPVPPLEDMELYQSFTDEFFGPAFAVLG
                     GA"
     gene            13287..14396
                     /locus_tag="ACHY1N_004235"
     CDS             13287..14396
                     /locus_tag="ACHY1N_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001494339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HFS4046441.1"
                     /translation="MTDTTMQLLSQGTDPVKMPDFDILAEGKTLSGVAERLMSLSLTD
                     NRGFEADQLTITLDDADGQLQLPPRGARLTVLIGWKGEPLTEKGTYIVDEIAHEGPPD
                     RLTVSARSADFRDEFNVKREVSWHDVTVERVVSAIAHRYGLKPQISEMLMDIEIDHAD
                     QTEESDMSFLTRMAEMLGAITTVKSGNLLFIMPGGGVNAQGQPLPSFAITRSSGDRHQ
                     FRIADREAYTGVRAYWLDLNYGKKKKVSVKRRKPSKPKKEKSSSREGDYMEGAEGNVF
                     VLRKTYQNEQAARRAAAAKWQQLQRGAASFSITLARGRAELYPEMHGTVTGFKSEIDN
                     QDWIIAKAEHTIDNSGFTTQLELEAKIPEWIAETE"
     gene            14622..>15958
                     /locus_tag="ACHY1N_004236"
     CDS             14622..>15958
                     /locus_tag="ACHY1N_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /protein_id="HFS4046442.1"
                     /translation="MNKKLYLFPDSNIFLQCKDLTQVNFSEITACDEVCIIITRPIQQ
                     EIDRQKGQGNSRLSKKARKAASLFNQVVDSTDMTLVIRERSPRVFLTMDLSLKPCEQL
                     SEQLDYQEADDRFVGIAAGYCADDPDSEVAIITNDSGPRFSAIKHNIICYKVPSSWLL
                     PAEPDEKDKQIKLLEAKLKQFTQSMPDFSIKVADDEQLNIVLPYYTALSEYEVDNLLC
                     QLTDAFPLVTNFDNEQTTPQSLEKIIKSFSQQEYFPVSADDISLYKEKHYPLWKKQCE
                     EILKNCHTHINPKAIKYPLSFLLQNTGYTIAERAVVTFTAKGDFRLCGFNWEIMEELT
                     ESKRIDLPSAPTAPKGKWRSVCGVTERMPYAWGALETPLSSIISKEIGPLLSLTPTER
                     DKNDFYYKEKRNEPVQVVSLECEEWRHQVKEEIFPLFVYTANKPKKVNGAIEV"
BASE COUNT         4044 a         4201 c         4029 g         3684 t
ORIGIN      
        1 gcacgtattg cccgcgttca tcagttcggt gagcgcgatc aggttgcgcc gggcattttc
       61 accgattacc cggtacgtga gctgctgggt atcagccagg cagatgagcg cctgatttat
      121 aacacggtgc tgggccggat tgcggaggct gtacggtgag cgcagaactc atgcgactgc
      181 tgagcaatat catccgcacc gggatcatct ctgaagttga tgagaagtcc tggtgcgtgc
      241 gcgttcgcag cggcgaactg gaaacaggct ggctgcgctg gaacaccacg cgcgcgggag
      301 ccttcaatgt gtggctgccg ccatcaccag gcgaacaggt agtaattgcc tgcattggcg
      361 gcaacccgga aaccgccatg ataattggca gtctgtggag tgatgccagt ccggcccccg
      421 gcaaacgcct gaaagaaatc gtgatcagcg cgccggacgg cgcggtgttc cgctacgacg
      481 cggacgcagg cgcactgagc gccagcggca tgaaaacggc cactttacag gcatccgtca
      541 gcgtgaaact ggacacgccc gtcgtggaat gcacaaacct tctgagaacg gcgacgcttg
      601 acgtcacaaa aggaggaaag atgagcggca atatcacgca cagcggcggc aacttcacct
      661 caaacggcat taccgtgcat acgcataaac acggtggcgt gaaaggcggc agcgattcga
      721 caggaggccc gcagtgacaa cccgctacac aggaatgaat ccggacggga cgggaaacct
      781 gaacgatatg gagcacctga aacagtcagt cagggatatc ctgaccaccc cgctggcaag
      841 ccgggttatg cgacgggaat atggcagcct tgtgcctgat ttgattgacg aacccatgaa
      901 taacaccacg cgtctgcaat gcatgagtgc tgccgtgatt gcgctgacac gatgggaacc
      961 ccgcattgcc ctggatgcca tcgacgttgt ctggaaagcg ggaggccgcg ccggggtgac
     1021 gctgtcgggc actgtcatgc agaccatgca gaatgttgag ttaaccatca cgctgaggga
     1081 gtaaatcatg cccgccgttg acctttccca gttaccggaa cccgccatca tcgcggagcc
     1141 tgactttgag gcaattctgg ctgacacaaa ggccatgatg attgcggctt atcccgccga
     1201 acagcgtgaa gccgtctccg ccgcgctgga gctggaatcg gaacccctga acgttatcgc
     1261 ccagacaaca gcgtttcgtg aaatgctgtt acgccagcgg gtcaatgagg gggcacgcgc
     1321 ctgcatgtta agccacagcg ccgggacaga cctggacaac ctcgcgggca atatgaacac
     1381 aaagcgcctg accatcactc cggcaacgga taccaccgac gcagtgatgg aaagtgacac
     1441 ctcgctgaga ctgcgggcgc agcgggcgta cgatggtctg agtgttgctg gcccgtcagg
     1501 tgcatacgag tattttgccc gcagcgccag cggtctggtg cgtgatgcgc gggctatcag
     1561 tccgtctccg gcaaatgtga cggtttccat cctgtccact gaaggcgacg gcacagcaac
     1621 ggaggcgttg cttaataccg ttcgcgccgt tctgaatgca gaggataccc gcccggtggc
     1681 cgaccgcctt actgtacaga gcgccagcat cgtgacatgg cggctgaatg caaaactgta
     1741 cttttacccc ggcccggaat ccgaacctat tctggcggcg gctgaatcgt cgttcaggaa
     1801 gtggctggct gagcaggggc ttatcggtca ggacgtggcg ttgtccgcca ttgctgccgc
     1861 actgcatgtg cacggtgtgc aacgcgtgga gataatcgaa cccacacaga atatggccat
     1921 cagcgacata caggcggcgc gctgtgagtc gttcaccatc agcgaaggtg ggcgcaatga
     1981 gtaattcact gttaccacca tcagccagca gtttcatgcg ttgtgccgaa gctgtcggaa
     2041 cgcgcattac agacatcccg gtagacctca acacgctgtg gtcgccggac acctgcccgg
     2101 tgcacctgct gccttatctc gcctgggcat tttccgttga ccgctgggat cgcaactggc
     2161 cggaagagac aaaacgacag gtgattcgtg atgcatggct gatacaccga cacaaaggga
     2221 ccatcagcgc actgcgcagg gccattgagc cgctgggata cctcattcgc gtgtctgagt
     2281 ggtgggagtt cggcggagaa ccgggaacat ttaccgttga agtcggcaca ctggacagtg
     2341 gcgtgacgga ggaaatgtat ctggaaatgg agcggttgat tgctgatgcc cgtccggtca
     2401 gccgccacat gacagggctg aatatcattc aggaaattcc gggggatatt ttcgcagcgg
     2461 cggcaactta tgacggtgaa gttattacca tttatccgga cgattaagca tgagtaccac
     2521 aacacgaaaa tttaaaacca ttatcactga tactggtgcc aaaaaattag ctcaggcagc
     2581 cgcgccagat ggtaatcctg tccgcctgac tcacatggcc gtgggcgatg gtggcggcac
     2641 gttgcccaca ccagacagta agcagacccg tctggtgcat gaggtgtggc gacatactgt
     2701 taatcgcgtc atcctggacg caacacatca gaaccgcatt attgcggagc tggttattcc
     2761 tcctgaaacg ggcggattct ggatccggga aattggtgta tttgatgagc acggcgattt
     2821 gatcgcggtg ggcaatactg cggaaagtta caagccaacc gttgccgaag gatccggacg
     2881 tgcacaaaca tttcgcacca ttctgaccgt atccagcact gccaccgtgg cgcttaccgt
     2941 ggataacacc atggttatgg ccacagtgga ttacgtggat gacaaactga aagagcatga
     3001 acagtcacga cgtcacccgg atgcctcgct gaccgcaaaa ggctttgttc aactcagtag
     3061 cgccactaac agcgattctg aaacgctggc tgcaacgccg aaagcggtta aggccgcgca
     3121 tgacctggct aacggaaaat ataccgctca ggacgccacg acggcacgaa aagggatagt
     3181 ccagctcagc agtgcaacca acagcacgtc tgaaacgctg gctgcaacgc cgaaagcggt
     3241 taaggccgcg tatgacctgg ctaacggaaa atataccgct caggacgcca cgacggcacg
     3301 aaaagggata gtccagctca gtagtgccac caacagcacg tctgaaacgc tggcagcgac
     3361 accaaaagcg gttaaggcgg taatggatga aacgaacaag aaagccccat taaacagccc
     3421 ggcactgacc ggaacgccaa caacaccaac tgcacaacag ggaacgaata atacccaaat
     3481 cgcaaacacg gctttcgtta tggccgcgat tgccgcactt gtagactctt cacctgacgc
     3541 actgaacacg ctgaacgagc tggcggcggc gctgggcaac gacccgaatt ttgcgaccac
     3601 catgactaac gcgcttgcgg gtaagcaacc gaaagatgcc accctgacgg cgctggccgg
     3661 gcttgctact gcggcagaca ggtttccgta ttttacgggg aatgatgttg ccagtctggc
     3721 aaccctgaca gaagtcgggc gggatattct tgcgaaatcg accgttgccg ctgttatcga
     3781 atacctcggt ttacaggaaa cggtaaacaa ggctggtaac gccgtccaaa agacaggcga
     3841 tatcttgtcc ggtgggctta cttttgaaaa cgactcaatc cttgcctgga ttcggaatac
     3901 tgactgggca aagattggtt ttaaaaatga tgccgacagc gatactgatt catacatgtg
     3961 gtttgaaaca ggcgacaacg gcaatgaata tttcaaatgg agaagccgcc agagcaccac
     4021 aacaaaagac ctgatgaatc ttaaatggga tgctttgtat gttcttgtta aagctctttt
     4081 cagcagtgaa gtaaaaatat cgacagttaa tgcactgagg atatttaatt catcttttgg
     4141 tgccattttt cgccgttctg aagaatgcct gcatatcatc ccgacacgag agaatgaggg
     4201 agaaaatggt gatatagggc cactacgccc ctttacgctt aatcttagaa ctggtcggat
     4261 aagcatgggg catggtcttg atgttacagg ggatatattt gcaaaccgtt ttgcaattaa
     4321 cagtagtacc ggcatgtgga ttcatatgcg tgaccagaat gttattttgg gacgcaatgc
     4381 ggtatccacc gatggtgcac aggcattact tcgtcaggac catgctgatc gcaaatttat
     4441 gattggtggg ctgggaaata agcaatttgg catctacatg attaataact caaggacagc
     4501 taatggcacc gatggtcagg cgtacatgga taataacggg aactggcttt gcggttcgca
     4561 agttattccc ggcaactatg gcaattttga ttccagatat gtgaaagatg ttcgacttgg
     4621 ttcacagcaa tattatggag tgaacaactg gcaaacatgg aatttccagt gcccgtcagg
     4681 tcatgtattg tctggtatta atgttcagga tacagggtcc aactctgccg ataatatagc
     4741 gggcgtttat tacagacccg ttcaaaagta tataaatggc acctggtata atatagcgag
     4801 cgtttaatat gatgcactta aagaacataa aagcgggtaa tgctaaaaca ctggaacagt
     4861 atgagttaac aaagaagcac ggagtcatct ggctttactc tgaggacgaa aaaaactggt
     4921 atgaggaagt gaaaaacttt cagccagaca ccataaagat tgtttacgat aaaaatcaga
     4981 ttatagtcgc tatcaccaga gatgcttcaa cgcttaatcc tgaaggtttt agcgttgttg
     5041 aggttcctga tattacctcc aaccgacgtg ctgacgactc aggtaaatgg atgtttaagg
     5101 atggtgctgt ggttaaacgg atttatacga cagatgagca gcaacaacag gcagaatcac
     5161 aaaaggccgc gttactttcc gaagcagaaa gcgttattca gccactggaa cgcgccgtca
     5221 ggctgaatat ggcgacggat gaggaacgcg cacgactgga gtcatgggaa cgctacagtg
     5281 ttctggtcag ccgtgtggat acggcaaatc ctgaatggcc acaaaagcct gaataaaaat
     5341 taaggcccgc tatcgggcct tgtctcattc aggttgttcg ggaaacgtta ctggcaggct
     5401 ggaagtgtct gtagattcga ctttctgcgc aaagagcatc cactctgtta atttttgttt
     5461 atgctcgtcg gaaatgatgc ccagccgtag ctgtgagtcc catagctggg ttttatccct
     5521 gacgagctgt agcaggcttt gcttttcatt ttccgcctgc tgcctctgct cttcctcggt
     5581 ataagttcgc tttaccacta cgccatcttt gaacatccat ttacccgaaa tgtcagcacg
     5641 gcgatttgct gtaatatcag gtaattcaac gacgcttgcg ccttccggat taattgctga
     5701 aacatccttt tcaatacaaa taataacgcc gttatggcca tagaccattt tcaaagtgtc
     5761 tggctggaaa ttcttttgtt cctcatacca gttttttcca tcatctgaat aaagccattt
     5821 gatgttaaat tgctttgtta gctggtattg ctcttttgtt ttagggttgc cagcagtaat
     5881 gttttttaag tgcatcatcg ttaaatactc cccgcgttat accacgtccc attaatgcaa
     5941 tactgaattg gccttgcctg agttgtatca attaattcat cacggtttcc gttaactgaa
     6001 cccgtaacga cataacctga cctgtcagac cagccggggc cattccatgt ctgaacagat
     6061 gacagaccgc caaggcgaat acctgtaata aaccttgagt tacattctgc ctgcgtgtat
     6121 gcaccaacat ctcccgcaga gggtttgcgg gtcgtggtgt aaaactctga ccagtcagcc
     6181 tcaaatccat aaccatcacg cgctgaacga taaaaaatac cgccgttcct gtaattcacg
     6241 cggaactgta cagcagggca gctccccgta ttcatattga agtggaggat taatgtcgat
     6301 gcgccaccaa tgtttgcgtt atagaccccg ctattccagt tccagccaac agctttatca
     6361 tttccgacag tgcttcctgt ttgccctaaa gcaaatgcag gttgttgatt tttcgtgttg
     6421 tagtctcgtc gccagccagg agcataagca tcaccatgat taatataagt gaattgagcg
     6481 ttagtaattc cgccaccgct ggacgtgctc ggcgtagtaa cgcgtatggt cattgcgccg
     6541 cgagtgccaa taacttccac cacagcacct gcaagacaaa tatttccgca acctgtatct
     6601 gtaatgacct tattatttgc ataagcccat gagcctttgc acatccagta aggatggtta
     6661 aatgctccct gactctccag ccacgaaata aattgcgcgg ttgtccagac ctgactatcg
     6721 ccaccaatat tcagccatga gctatatgcg cggcaggccc caatattttt ggtgaaggta
     6781 tctttccccg gaatatctgc gccgttctgg tttttctgta atgcgccaga agcctgattt
     6841 accgtttcct gtaaaccgag gttttagata atggccgttt ccggcctgca tggcatgatt
     6901 tgcgcttttg gacgggagat tcagcgtgct gattggctat gtaagggtat caacaaatga
     6961 ccagaataca gacctgcaac gaaacgctct tgtttgtgca ggatgtgaac aaatatttga
     7021 agataaatta agcgggacaa agacagaccg accgggatta agacgcgctt taaagcgcct
     7081 tcaaaaaggt gacacgctgg ttgtctggaa actggatcgc ctcgggcgaa gcatgaaaca
     7141 tctgatttct ctcgtcgggg aactacggga gcgaggaatt aattttcgca gtctgaccga
     7201 cagcatagat acatcttctc caatggggcg ttttttcttc cacgtgatgg gtgccctggc
     7261 tgaaatggaa cgtgaattaa ttgttgaacg tacactggcc gggctggcgg cagcgcgcgc
     7321 aagggggcgc acaggcggac gtcgaccgaa gctgacaaaa gaacagcatg agcaaatagc
     7381 aaggctaatc aaaaacgggc acgacagaaa acaactggca ataatttacg gcattggcac
     7441 atcgacgatt tatcgttatc accctgtagg cgatatacag actgaagaaa caaccgggca
     7501 gactcaggaa aatgaaaacc gctaatctga ccattagcgg tttttgtgtt aaatcagaac
     7561 agtcctttaa ctgaactggc cgcgctgtta agagatgatg tcaccttatc tttgaagccg
     7621 gacagcatat cactgaacga tgaggattgc aggcgctccc gcaaatcctc atcacagcgt
     7681 tcaagagtca gtgaaaattc tatctttttc gccttaccgt agcgatcaaa ctcggagcgg
     7741 gtcgtattcg tttcagtcag gacatatatg ccgtaaatct gcccgacgcc atcaatcaaa
     7801 ggccagggtc gtcctgtata cgcctgcgtg gccagcagcg acagcgacac ttcgccacct
     7861 gtaatttcag gataaagcac accagaaaga acgatgcgat catcacctgc accgatatac
     7921 tgccagcttg ctgaacggtt aacgcgttca tttttcacat gccgccagct tttgttttgc
     7981 tgtaactgct gatgcggcag cgtgcgcagc tcaaaaacaa acatgccgta gatcatcatc
     8041 atggccatga ctcctcaatc tttatcgtaa aaactgccac gcccggcacg agcgcgccgt
     8101 tccatttctg ccctgaccat ttcaccgacc agtttggcca gttcgcgggg attctgtgta
     8161 acgacgttat gcagatgaac atgaatttca ccgccaaatc cggaggcaac aggctcccgg
     8221 ttacgcgaag gtgctggggt tgatgccact ggcgatcgta tggcctccgc caccgggcgg
     8281 gagctggccg caacaacagg aaccagagcc ggaggcagcg gagccgggac cacgggtgtg
     8341 atcttaattg cgggggcagg cttactgacc tgcgcaatct tccgctcctg ccactcccca
     8401 cgaacagcaa gtgcgcgggg caggttctta aagacaatat cgccggggcc aatgcgtttt
     8461 ttcgtctcat caaccagctt acctgtgtta tcagcaattt tgctgagtct gcgtagcgta
     8521 ccggtattgc tgtctgtgag cggtttattg tctttgggtt tatcacctcc ggtgccattg
     8581 ccattttcta caggcttcgg cggattgatt ttcgccaggt ccccctgaag caaggcaacc
     8641 ttgtcctgga gaatagccgc acgctgtgcg tcttcgattt tctttctcgc cctttccgct
     8701 tcatccggaa gcacaccgag tttttcaagt atccacgcca gcgtatccag caacattttt
     8761 gcaggcgtca gaacaagctg taacgcacca ccaagaacgt taccgaatat ctcgccagca
     8821 ctggtacatt tatccagcgt ttccttgctg gactccatcg gtgacaacag cgatttaaac
     8881 cagttaaaca cctggctgat cccgcttccg attgcgtcaa aaacagggcc aaaccgttca
     8941 aaggtttcgc gcaacggggt cagcctttcc ataatcccgc tgaacacccc ggcaaaaaat
     9001 gccctgatgg gatcccaata tttccagata agaatggcag ctccggcaag cgcagccacg
     9061 ataagaccaa ccggactgaa cagcgccccg atagcacctc ccagcaaaga aacggacccc
     9121 gtcaccattc cccatagtgc tggcagaacc ctgacagcat tcattgatcc ggtcaggagg
     9181 gaaaaaccaa gacgcagttt tgccagcggg ccagcaagca caccaatagc cagcgacaac
     9241 gagccaaccg ttgcagtcat tgccagcaac gcaccgcctg ctatcagtag ctggcgcgtc
     9301 agtgcgggat gggcctgcgc cagcgccgtc acccttgata ccacccgcgt gagccactgc
     9361 gtgacagaac gcagcggacc gtcaatcaga tctgcaatgc ggatgcgcag cccttcccat
     9421 gcactgccga gtgatttcag atcgccgtca aggttgttgg ccataacctt tgctgtgcgt
     9481 tcagcctcac cgcgcgcgcc ttcaagttct tttctcagtt tgggtaagga accgtcaccc
     9541 gctgcatcaa cgagcgccat aaacgatgtg aaagcctctt ctccggcaat gtccttaaag
     9601 aacgataccc ggtcaacttc cccgtatttg cgggtggctt tataaaggtc ggccagcaca
     9661 tcctccatcg ggcgcatttt gccgttcgcg tcagagactg ccacaccaag ctctttcagc
     9721 gcctctgctg ctgcctttgg cggtgatgcc agacgagcca ggctggcacg cattgccgtc
     9781 ccggcatcac tccctctgat acccatattc gccagcacgc ccgccatcgc tgcggcctgc
     9841 tccagcgata ttcccagctt acctgccacc ggacctgcat atttcatggt ttcgcccagt
     9901 gcgcgaaggt cagtgttggt acgggtaaac gctgcagtga gtgtgtcacc gacccggtcc
     9961 atctggtcag cagaaaggcc gaactgcgtc aggatatttg agccaatatc cgccgtctct
    10021 ccgagatcca taccgccagc cgttgccatg ctcaacacgc cgggaagcgc agcctgaatg
    10081 gcctgcggtg tgaagccagc cattgcaaga aatgcctgcc cactggcggc atcgcctgcg
    10141 gtgaactgcg tttcagagcc aagttttaac gcctgctcac gcagcgcctt aaactgcggg
    10201 ctgttctggt caattcgcgt cagcgcctgc acacgggaca tctctttccc gaatccgata
    10261 gcgggctgca aaaaacgccc ggcagcatag ccgccagccg ctgccgcacc agttgccagt
    10321 gcaccacctg ttttcagttt tcccgctgtt tcctgcgcgc gcgaataccg ctcacgcgcc
    10381 cgcgttacac gcacaagcgc ctgccgttcg cgttcaagct ggttgttgta ctgttcggtg
    10441 cgtctgatgg cctgctggat ggtgttatcg ctgcctgtca gggaaatgcc gtggcgtttc
    10501 agctctccgc caagctcccg cattttctga atttcccgcg tgcgcgattc attcaggcgt
    10561 tcaagccggg tgcttaactg ctgcatcagc ttttgttgtt tttcgctgag cactgtaccc
    10621 gtgcgttgta actgattaag ggcgttaagc tggcgtcgtg cttttacgat gcccgcatcc
    10681 gctttactga cagcgtcgcg ggcgcgctca aatgaacgcg cctgacgctc gagatttttg
    10741 atcgccccct gcgttcgctg gatggagtca ccaaaccgcc ccatcaggcg gcgggcgttt
    10801 tcggcaggcc gggtcagcct gtcaacggcg ctgaaagcga cccggatatc aagagtcttc
    10861 attgtctgca ttcccgctgc gaagtgccgc ccgctcacgc cagctaacca cttcgccggg
    10921 cgtcatcatg aagatttcgg cgggcgacca gttaaaaatg gcggcaatat ccgccacaaa
    10981 gtcttctatg tgctcaaagc acacaaccgt gatcaggctt ccgtcgcctg ttcgttcttc
    11041 ccgccagagt ccgcaccgct caaaaaattt acggcaacca cacataactg aataaagtca
    11101 cgggatgcca tttttttgat cgtcacttca tccagtcgcg gtgatgtcac gcgtgacagc
    11161 agcgtaaaca tggattccgc tttcagattc agcacatcag acagcgacaa atttcgcaga
    11221 gatccagcct gctcaatagc tccggtgatc tccacatacg tgattttttc gccgcctcgc
    11281 tcaattggtt gggtaagttt tacgccatgc tcactggttt ctttcactgt gtcagcaact
    11341 accgtgtttt cggtatcgat gtttttcgtc tctttcatca ggaaactcct ttcagtcaga
    11401 ggcgacgcac tgcgccgcct gcatattact tatcagccaa gcccaagtgc ggaacggatg
    11461 cgatcaggca caatgtcctt gccgtccttc cggtaaatga agttcagcag gtcaatctcc
    11521 cacaacgggc gatcgttaac actcagcttg tagtaggtgt ttttaatggc gtaagtgtgt
    11581 gatgtggctt cgccctgttt ggcttccccc atatcaattt ccgtcacacg tccgcgcatt
    11641 tcgacttcat acaggtcgct ttctgcatcg gtgtagtatt cacccgcaaa acgcagcagc
    11701 gtgccgtcaa tcgtgccgcc atacttaagg aacagctcac gaactgcgcc ccccatgaca
    11761 aagctcgcat caagcgcgga gtcgtccaga ccgagatcaa tacttaccgc acccatcatg
    11821 ccaccacccc ggtagctgtc ggttttgcgc gtcagcttag gcagagtgac ggacgtcacc
    11881 ttacccactt cgttttcacc atccacaaac agcgtaaaaa agcgaagatg ttttggtaca
    11941 gccatcaggc acctcccagc accgcaaatg cgggaccaaa gaattcatca gtaaacgact
    12001 ggtaaagctc catgtcttcc agcgggggaa caggcgtata tttgtagcga atacgcacgc
    12061 gcccctgacg taaattcgtg gtgccgttat ccaccacgtc ataccagcac gacgccccaa
    12121 tcagtttccc ggcagtaacc agtgaatcca gttttgccct gatggcactg ataacatctt
    12181 tcacgttcgc aggcgtcagt ggactgtcga tggtttcaaa ctgcgcttcc gcaattgaat
    12241 cagccagcac ctgtgcggtt cgggtataca cctcaaagat gtaggcgttc gtttccggtg
    12301 tgcggttgcc ccagaagcgg aacccgttgc gacgaataat ggtcgtgatt tctttgttgt
    12361 tgaggctgtt ggcatcgctg tcttcggcct gcaacgacca gaacacatgc ctcgacatcc
    12421 ccagcacatt tttaaccgga acgttggaca gtgatttgtg ccagccctgc tcatggtcaa
    12481 tgtacgcacg aaggccgcac gcataggcag gcgcggggaa cgtttcgttt ttgccacttt
    12541 tcgggttgta ggcgatgaag tccggccata agagcatcac ctcacgttcg ttgaatttct
    12601 ggcggtaggt aatcgcctca gccatcgtgt tacagccgtg acatgaggca tacacaaacg
    12661 cgcgcagttt acccgcaatc acgcacaggg attttgttac cgcctccgtg tccagctccg
    12721 gcgcggccag aatacgcgga cggtatccga tgctttcatc ctgctctgca acaagcagcg
    12781 catacatccc cgtatagctg ccgtcagatt cagaaccacc gataaccagt tgatcctgcg
    12841 tttttccgtc ttcttctttg tgttcagcca cgcgaacgac gatcaccttt gtgctcacct
    12901 ggtctgcgat ggccttaagc gcacgataaa gcgtccccgt tgttccgcat tttcccagca
    12961 cgtcattgac gcgggtcagc agtgtgggct tgttcagcgg gaacagctcc gcgtccgcat
    13021 catccgccgt tgccacgata ccgataacac tggaatcaac atcattaatc gctgttacca
    13081 ggtcggtact ttccgtaaca cgggcaccat gaaaacgagt ttcactcata gcttcagccc
    13141 cttgtatccg ttaaatgatt cggcaacaat catcacccac cacgcgcgta atctcacccc
    13201 tgcgccgttc tcccgacccg gcgacaacaa aaagcagtaa ccccctccgc acgcacatgc
    13261 gaccatgccg cacagggagg gagcagatga ccgacaccac catgcaattg ctcagtcagg
    13321 gcacagaccc cgtgaaaatg ccggattttg atattctcgc ggagggtaaa acgctgtcag
    13381 gcgtggcaga gcgcctgatg agcctgtcac tgaccgacaa ccggggattt gaggcggacc
    13441 agctcaccat cacgctggat gatgcggatg gtcagttgca gctaccgcca cggggcgcgc
    13501 gcctgacggt tctcattggc tggaaaggag aaccgctgac agaaaaaggc acttacattg
    13561 ttgatgaaat cgctcacgaa ggaccgccgg acaggctgac tgtttcagcc agaagcgcag
    13621 attttcggga tgaatttaac gttaaacgtg aggtgtcctg gcatgatgtg accgttgagc
    13681 gtgtggtatc cgccatcgct catcggtatg gtctgaaacc gcaaatcagc gaaatgctga
    13741 tggatatcga aatcgaccac gccgaccaaa ccgaagaaag cgacatgtcc ttccttacgc
    13801 gcatggcgga aatgctgggc gcaatcacca cggtaaaaag cggtaatctg ttattcatca
    13861 tgcccggtgg tggcgtgaac gcacagggcc agccgttgcc ctcgttcgcc atcacacgca
    13921 gcagcggcga tcgccatcag ttccgcattg ctgaccgcga agcgtatacg ggggtacgcg
    13981 cttactggct tgatcttaat tacgggaaaa agaaaaaagt cagcgtgaaa cgccgcaaac
    14041 cgtcaaaacc aaaaaaggag aaaagcagca gccgggaagg cgactatatg gaaggtgcgg
    14101 aaggcaacgt gtttgtgtta cgcaaaactt atcagaacga gcaggcagca agacgcgcag
    14161 cggcggcaaa gtggcagcag ctacaacgcg gagccgcatc attctccatc acgctggcgc
    14221 gtggacgtgc agaactctac cccgaaatgc atggcacggt aacaggattt aaaagcgaga
    14281 ttgataatca ggactggatt attgcaaaag ccgagcacac cattgataac agcggcttta
    14341 ccacgcagct tgagcttgag gcaaaaatcc cggaatggat agcagaaaca gagtgagcaa
    14401 cttaaatgta ttaactcaga acggatcaac acactcacaa catagagtca atatagctgc
    14461 tcgctttgtt ccagcaagga tgcctatttc taaggaaaaa cagagcagaa acatatggtg
    14521 ttttcctacc tgacatcagg ggtggtaaga atcatgcttt gataaccaat tgataactat
    14581 tattatatta atctaacacc attgacatag ttgaggtttg aatgaacaaa aagctgtatt
    14641 tattcccaga ctcaaacatt tttctacaat gcaaggactt gacgcaggta aatttttccg
    14701 agattactgc ttgtgatgaa gtatgtatca ttattacaag gcccattcag caagagattg
    14761 accgccagaa agggcaaggt aattcccgcc tatccaaaaa agcaaggaag gctgctagcc
    14821 tatttaatca agtagttgat tcaactgaca tgactcttgt tattcgtgaa cgctcgccgc
    14881 gagtttttct taccatggat ctaagcctga aaccatgtga acagttatct gaacaattgg
    14941 attatcagga ggccgacgat cgttttgttg gtattgcggc agggtattgc gctgacgatc
    15001 cagattcgga ggtggcaatc attaccaatg atagcggtcc acgtttttca gcaataaaac
    15061 ataatataat ctgctataaa gtgccttctt catggttgct tcctgctgag ccagatgaaa
    15121 aggataaaca aattaaattg ctggaagcta agctgaagca attcactcag tccatgcccg
    15181 atttcagcat taaagtagcc gatgacgagc aattaaatat tgtacttcct tattatacag
    15241 ctttatctga atatgaagtt gataatttgc tttgtcaact aacggatgca ttcccattgg
    15301 ttacaaactt tgacaatgaa caaactaccc cacaatcact agaaaaaatc atcaagtcat
    15361 ttagtcaaca ggagtatttc cctgtatcag cagatgatat ttctctttat aaagaaaaac
    15421 attatccact ttggaaaaag cagtgtgaag aaatactgaa aaactgtcat actcatatta
    15481 atccgaaggc aataaaatac ccgctgtcgt ttttattaca aaacacaggt tatactatcg
    15541 ctgaacgtgc tgtggtaaca tttacagcaa aaggagattt tcgtctgtgt ggatttaatt
    15601 gggagataat ggaagagctg actgaaagca aaaggattga cctaccttca gcccctaccg
    15661 cccccaaagg aaaatggcgt agtgtatgtg gcgtaacaga aagaatgcct tacgcttggg
    15721 gagctttgga aacaccgcta tccagtataa tttcaaaaga aattggtcct ttgttatctc
    15781 ttactccaac agaaagggat aaaaacgatt tttattataa agaaaagaga aatgagccag
    15841 ttcaagttgt atcgctggaa tgcgaagagt ggcgtcatca agtcaaagaa gaaatattcc
    15901 cgttgttcgt atatacagcc aacaaaccaa agaaagtgaa tggtgcaatt gaggtgag
//
LOCUS       DAZUDJ010000090        15889 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.090, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000090 DAZUDJ010000000
VERSION     DAZUDJ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15889
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.090"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..499
                     /gene="ydeR"
                     /locus_tag="ACHY1N_004237"
     CDS             <1..499
                     /gene="ydeR"
                     /locus_tag="ACHY1N_004237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4046443.1"
                     /translation="RLHKRFLLATFCALFTATLQAADVTITVNGRVVAKPCTIQTKEA
                     NVNLGDLYTRNLQQPGSASGWHNITLSLTDCPVETSAVTAIVTGSTDNTGYYKNEGTA
                     ENIQIELRDDQDAALKNGDSKTVIVDEITRNAQFPLKARAITVNGNASQGTIEALINV
                     IYTWQ"
     gene            558..1472
                     /gene="ydeQ"
                     /locus_tag="ACHY1N_004238"
     CDS             558..1472
                     /gene="ydeQ"
                     /locus_tag="ACHY1N_004238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4046444.1"
                     /translation="MGKTISIKVLFGIYLLLMAGKVFAFSCNVDGGSSIGAGTTSVYV
                     NLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNN
                     VTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPVGAAGGVVIKAGEVIARIHMYKIATL
                     GSGNPRNFTWNIISNNNVVMPTGGCTVDSRNVTVDLPDFPGSAEIPLGVYCSSEQKLS
                     FYLSGATTDSSRQVFANTAPDATKASGVGVSLMRNGKILATGENVSLGTVNKSKVPLG
                     LSATYGQTGNKVAAGTVQSVIGVTFIYE"
     gene            1806..4085
                     /gene="ydeP"
                     /locus_tag="ACHY1N_004239"
     CDS             1806..4085
                     /gene="ydeP"
                     /locus_tag="ACHY1N_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance putative oxidoreductase YdeP"
                     /protein_id="HFS4046445.1"
                     /translation="MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKP
                     EGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHE
                     LEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
                     FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHN
                     PGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYY
                     NVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEW
                     KDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNI
                     GKPGAGICPLRGHSNVQGDRTVGITEKPSAEFLARLGERYGFTPPQAPGHAAIASMQA
                     ICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILP
                     VLGRSEIDMQKSGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQAALPQS
                     VVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANF
                     ITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAK
                     ICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHD
                     PLSGIPGYKSIPVELEPSN"
     gene            4333..4530
                     /gene="safA"
                     /locus_tag="ACHY1N_004240"
     CDS             4333..4530
                     /gene="safA"
                     /locus_tag="ACHY1N_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system connector SafA"
                     /protein_id="HFS4046446.1"
                     /translation="MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLG
                     ISEMGRIARDLTHFIINSLQD"
     gene            4605..5366
                     /gene="ydeO"
                     /locus_tag="ACHY1N_004241"
     CDS             4605..5366
                     /gene="ydeO"
                     /locus_tag="ACHY1N_004241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response transcriptional regulator
                     YdeO"
                     /protein_id="HFS4046447.1"
                     /translation="MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPY
                     ERHFKEIGFNENTIKKYLQCTNIQTVTMPVPAKFLRASNVPTGLLNEMIAYLNSEERN
                     HHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCL
                     YISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYA
                     FRKHFGNSPKRVSKEYRCQSHMGMNTGNTMNALAI"
     gene            5770..7452
                     /gene="ydeN"
                     /locus_tag="ACHY1N_004242"
     CDS             5770..7452
                     /gene="ydeN"
                     /locus_tag="ACHY1N_004242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416015.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HFS4046448.1"
                     /translation="MKSALKKSVVSTSISLILASGMAAFAAHAADDVKLKATKTNVAF
                     SDFTPTEYSTKGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAI
                     EAAQKSTPTLLSLMDEGVRFTNGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGI
                     PLTETFLPELFQNHGYYTAAVGKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQ
                     NRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDEAIGVVDRAKTLDQPF
                     MLYLAYNAPHLPNDNPAPDQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQ
                     YDNTIILFTSDNGAVIDGPLPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKL
                     ISAMDFYPTALDAADISIPKDLKLDGVSLLPWLQDKKQGEPHKNLTWITSYSHWFDEE
                     NIPFWDNYHKFVRHQSDDYPHNPNTEDLSQFSYTVRNNDYSLVYTVENNQLGLYKLTD
                     LQQKDNLAAANPQVVKEMQGVVREFIDSSQPPLSEVNQEKFNNIKKALSEAK"
     gene            7504..8661
                     /gene="ydeM"
                     /locus_tag="ACHY1N_004243"
     CDS             7504..8661
                     /gene="ydeM"
                     /locus_tag="ACHY1N_004243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0018209 - peptidyl-serine modification
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HFS4046449.1"
                     /translation="MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIK
                     QYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEW
                     CAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQVEFNTLTVI
                     NNVNVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAY
                     GKFMSTIFMQWVKNDVGEIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIY
                     ECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRISAKCQQCAYKPICNGGCPKHRIT
                     KVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN"
     gene            complement(8627..8749)
                     /locus_tag="ACHY1N_004244"
     CDS             complement(8627..8749)
                     /locus_tag="ACHY1N_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046450.1"
                     /translation="MTKHPTGIYVGCLVKVIRRRLRMELKESVINYSPFVLQHP"
     gene            8952..10637
                     /gene="yddA"
                     /locus_tag="ACHY1N_004245"
     CDS             8952..10637
                     /gene="yddA"
                     /locus_tag="ACHY1N_004245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFS4046451.1"
                     /translation="MITIPITFCMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILG
                     VVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPALLGIFVLISVNKTWLIKLLTIR
                     WREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQ
                     SLSMLITFTVILWQSAGTLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRP
                     LNVEKQRSEATFRTNLVQHNKQAELIALSNAESLQRQELSDNFHTIKENWHRLMNRQR
                     WLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSRQAFMLVSNNLSWFIYKYDE
                     LAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVANASIRTPDNKIILENLNFHVSP
                     GKWLLLKGYSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQTPLIKSGLLKEIICK
                     ALPLPVDDKSLSEVLHQVGLGKLAARIHDHDRWGDILSSGEKQRIALARLILRRPKWI
                     FLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLADDICDISAVL"
     gene            10675..13047
                     /gene="yddB"
                     /locus_tag="ACHY1N_004246"
     CDS             10675..13047
                     /gene="yddB"
                     /locus_tag="ACHY1N_004246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HFS4046452.1"
                     /translation="MKRVLIPGVILCGADVAQAVDDKNMYMHVFEEMTVYAPVPVPVN
                     GNTHYTSESIERLPTGNGNISDLLRTNPAVRMDSTQSTSLNQGDIRPEKISIHGASPY
                     QNAYLIDGISATNNLNPANESDASSATNISGMSQGYYLDVSLLDNVTLYDSFVPVEFG
                     RFNGGVIDAKIKRFNADDSSVKLGYRTTRSDWLTSHIDENNKSAFNQGSSGSTYYSPD
                     FKKNFYTLSFNQELADNFGVTAGLSRRQSDITRADYVSNDGIVAGRAQYKNVIDTALS
                     KFTWFASDRFTHDLTLKYTGSSRDYNTSTFPQSDREMGNKSYGLAWDMDTQLAWAKLR
                     TTVGWDHISDYTRHDHDIWYTELSCTYGDITGRCTRGGLGHISQAVDNYTFKTRLDWQ
                     KFAVGNVSHQPYFGAEYIYSDAWTERHNQSESYVINAAGKKTNHTIYHKGKGSLGIDN
                     YTLYMADRISWRNVSLMPGVRYDYDNYLSNHNISPRFMTEWDIFANQTSMITAGYNRY
                     YGGNILDMGLRDIRNSWTESVSGNKTLTRYQDLKTPYNDELAMGLQQKIGKNVIARAN
                     YVYREAHDQISKSSRTDSATKTTITEYNNDGKTKTHSFSLSFELAEPLHIRQVDINPQ
                     IVFSYIKSKGNLSLNNGYEESNTGDNQVVYNGNLVSYDSVPVADFNNPLKISLNMDFT
                     HQPSGLVWANTLAWQEARKARIILGKTNAQYISEYSDYKQYVDEKLDSSLTWDTRLSW
                     TPQFLKQQNLTISADILNVLDSKTAVDTTNTGVATYASGRTFWLDVSMKF"
     gene            13104..15887
                     /gene="pqqL"
                     /locus_tag="ACHY1N_004247"
     CDS             13104..15887
                     /gene="pqqL"
                     /locus_tag="ACHY1N_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310126.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFS4046453.1"
                     /translation="MRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLGNGLRYMI
                     YPHAHPKDQVNLWLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMG
                     LRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVI
                     TEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQP
                     NNMTFIVVGDIDSKEALALIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRV
                     NGIALYYRLPMVQVNDEQSFIEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVK
                     IAPDYQSLFFRVNARDDNMQDAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAV
                     DQQAERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQ
                     DAFWEQMVNNELAAKKALSPAAILALEKEYANKKLAAYIFPGRNLSLTVDADPQAEIS
                     SKETLAENLTSLTLSNGARVILAKSAGEEQKLQITAVSNKGDLSFPAQQKSLIALANK
                     AVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARTNNPEPGFQLINQRIT
                     HSTINDNIWASLQNAQIQALKTLDQRPAEKFAQQMFETRYADDRTKLLQENQIVQFTA
                     ADALAADRQLFSSPADITFVIVGNVSEDKLVALITRYLGSIKHSDSPLAAGKPLTRTT
                     DNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMALDAFNVALAKDLRVNIREQASG
                     AYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQ
                     QNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLS
                     YPVNTYTGVLLPK"
BASE COUNT         4623 a         3473 c         3512 g         4281 t
ORIGIN      
        1 aagacttcac aagaggttcc tgttagctac gttttgcgcg ttattcacag caactctcca
       61 ggccgccgat gtcactatca ctgttaatgg tcgggtagtc gctaaaccct gcactattca
      121 aaccaaagaa gctaacgtta atctcgggga tctttatacg cgcaatctgc aacaacctgg
      181 ttctgcatct ggctggcaca atattacttt gtcattaacc gattgtccgg ttgaaacaag
      241 tgcagtgacg gcaatcgtga caggttcaac tgacaatacg ggttattaca aaaatgaagg
      301 tactgccgaa aatattcaga tagagctgag ggatgaccag gatgctgcgt taaaaaatgg
      361 cgatagcaaa acggttattg ttgatgagat cactcgtaat gcacagtttc cacttaaggc
      421 aagagctatc acggtgaatg gaaacgcaag ccagggaacg atcgaggcgc taatcaatgt
      481 gatctacacc tggcaataac gtcgattcga ttttcttagc cttcttttta aatcaatttt
      541 taaccttagg atatatcatg ggtaaaacaa tcagtataaa ggtcctgttc ggtatttatc
      601 ttctattaat ggcaggcaaa gtttttgcct tcagttgtaa tgtcgatggc gggtcaagta
      661 ttggagcagg tacaacctct gtttatgtta atctcgaccc tgtaatacag ccgggccaga
      721 atctggttgt agacttgtct cagcatataa gttgctggaa tgattacggc ggctggtacg
      781 acactgatca tataaacctg gtacaaggct cagctttcgc aggctcccta cagtcatata
      841 aaggatcgct gtactggaat aatgtgacct accccttccc gttgacgaca aataccaacg
      901 tattggatat tggtgataag acaccgatgc cattaccgtt aaaactctat attaccccag
      961 ttggggcggc cggtggagtt gtcataaaag cgggggaagt cattgctcgt attcatatgt
     1021 ataaaattgc aacattagga agcggaaatc cgcgtaattt tacgtggaat attatttcaa
     1081 ataacaatgt tgttatgcca acaggcggct gcaccgttga tagtcgtaat gtcactgtgg
     1141 atctcccgga ctttcctgga agcgcagaaa taccccttgg cgtatattgc tcaagcgaac
     1201 aaaagctctc attttatctt tcgggtgcca ccactgacag tagccgacaa gtgtttgcta
     1261 acacagcacc tgatgcaaca aaagcatcgg gagtgggtgt ctctctgatg cgtaatggaa
     1321 aaatactggc tacgggagaa aatgtctccc tggggacagt aaataaaagc aaagtacctc
     1381 tgggtttaag cgcaacctat ggacaaacag gaaacaaggt tgcagccgga accgtccagt
     1441 cagtcattgg tgtcactttt atctatgaat aattgtgatt ttgatcttag tctatgcgct
     1501 ccattcacga aaattgcgcg gataattatt ttgtgaaggc tattatccta cacctgtaag
     1561 aaaatccgcg cacaattgaa gccagagtct tattttttat attgaaaaat atgttaattt
     1621 aaacactatg agagatgatg cttaacttat cgtatttaat ctattgttta acgataatag
     1681 attaaaaata gaaagagagt agtcccctac tcttatatat ccatgttggc gataatccct
     1741 ttgtatgtac tgtgcatcat cgctattaca aatcctaata attcatttcc acacaggata
     1801 agtagatgaa gaaaaaaatt gaatcctacc agggtgctgc aggtggttgg ggtgctgtta
     1861 aatccgtagc gaatgcagta cgtaagcaga tggatatacg ccaggatgtt attgccatgt
     1921 ttgacatgaa taagccagag ggctttgact gtccgggttg tgcatggcca gatcctaagc
     1981 acagtgcgtc attcgacatt tgtgaaaacg gcgcaaaagc aatcgcctgg gaagtcacgg
     2041 ataagcaggt aaatgcctct ttctttgctg agaatacggt tcaatcatta cttacctggg
     2101 gagatcacga gcttgaggct gcgggacgtc tcactcagcc tttgaaatat gatgccgtca
     2161 gcgactgtta caagccatta agctggcaac aagctttcga cgaaattggc gcacgccttc
     2221 aaagctatag tgatcccaat caggttgaat tctatacttc gggccgcact tccaatgaag
     2281 ctgcctttct ttatcagctt tttgcccgtg aatacgggag caataacttt cccgactgct
     2341 ccaacatgtg ccatgaaccg accagtgtgg gtttggcagc gagtatcggc gtgggtaaag
     2401 ggactgtgtt gctggaagac tttgagaagt gcgatttagt catttgcatt gggcataacc
     2461 ctggtacaaa ccaccctcgc atgctgactt cgttgcgcgc tttagtgaaa cggggagcga
     2521 aaatgatcgc catcaatcct ctacaggaac gtggcctgga gcgatttacc gcaccgcaaa
     2581 acccgtttga aatgctgacg aactctgaga ctcagttggc cagtgcctac tacaacgtgc
     2641 gcattggtgg cgatatggcg ttgctcaagg ggatgatgcg cctgttaatt gagcgcgatg
     2701 atgctgcaag tgccgcaggt cggccctcat tgcttgatga cgaatttatt caaacgcata
     2761 ccgtcggctt tgacgagcta cgccgtgacg ttctcaattc cgagtggaaa gatatcgaac
     2821 gtatttctgg actaagtcag acacaaatcg ccgaactggc tgacgcatat gccgctgccg
     2881 aacgcaccat tatctgttac ggaatgggga tcactcagca cgaacatggt acccagaatg
     2941 tacagcaact ggtcaatctg ctgttgatga aaggtaacat tggcaagcct ggtgcgggta
     3001 tctgcccact acgtggccac tctaatgtac agggcgaccg aaccgtcggt atcaccgaga
     3061 aaccgtctgc agagtttctg gctcgcctgg gtgagcgcta tggcttcaca ccacctcaag
     3121 cacctggaca tgctgcaatt gccagcatgc aagcaatatg tacagggcag gctcgagcat
     3181 tgatctgcat ggggggcaac tttgcactgg caatgccaga tcgggaagcg agcgctgtac
     3241 cgttaacgca attagatctg gcggtacacg tagccactaa gcttaaccgc tctcatctgc
     3301 tgaccgcacg gcatagctat attctgccgg ttctgggacg tagcgagatt gacatgcaaa
     3361 aaagcggtgc gcaggcggta accgttgagg attcaatgtc gatgattcat gcctcgcgtg
     3421 gcgtgttaaa acccgccggt gtaatgctga aatcagagtg tgcagtggtc gcgggaatcg
     3481 cgcaggcagc actaccccag agcgtggtag cctgggagta tctggtggaa gattatgatc
     3541 gcattcgcaa tgacattgaa gctgtgctgc cagagttcgc cgactataac caacgcatcc
     3601 gtcatcccgg tggttttcac ctgataaatg cagctgctga aaggcgctgg atgacgccgt
     3661 caggtaaggc taatttcatt accagcaaag ggctgttaga agatccctct tcagcgttta
     3721 acagtaagct ggtcatggcg acagtacgca gccacgatca gtacaacacg acgatttatg
     3781 gtatggatga tcgctatcga ggggtattcg gtcaacgaga tgtggtcttt atgagtgcta
     3841 aacaagctaa aatttgccgt gtaaaaaacg gcgaaagagt taatcttatt gcgctcacgc
     3901 cagacggtaa acgtagctca cgccgcatgg atagattaaa agtggtcatt taccctatgg
     3961 ctgaccgctc actggtgacc tattttccag aatcgaatca catgctaaca ctcgataacc
     4021 acgatccatt aagtggcatt cctggctata aaagtattcc ggttgaatta gaaccatcaa
     4081 attaatgcct cttctcattt cttctgctgt catccgcaca gcagaagaat ccctcattga
     4141 ctattatcgc gcaatttgct cacatggatt aaattaaact acatactata agatataaac
     4201 ctctgcctac agctgtaaga aactccgctc agtactgaag tgccagtcct atttcctctt
     4261 ttctccagcc tgttatatta agcatactga ttaacgattt ttaacgttat ccgctaaata
     4321 aacatatttg aaatgcatgc gaccacagtg aaaaacaaaa tcacgcaaag agacaactat
     4381 aaagaaatca tgtctgtaat tgtggttgtc ttattactga cccttacgtt gatagccatt
     4441 ttttcggcaa ttgatcagct gggtatttca gaaatgggtc gcattgcaag agatcttaca
     4501 catttcatta tcaatagttt gcaagactga taataaacag aaaattataa atctgaaatg
     4561 ttaacaaagt atcgataaaa actttattgt tttaaggaga taaaatgtcg ctcgtttgtt
     4621 ctgtcatatt tattcatcat gctttcaacg ctaacatttt agataaagat tacgccttct
     4681 ctgacggcga gatcctgatg gtagataacg ctgttcgtac acattttgaa ccttatgagc
     4741 ggcattttaa agaaatcgga tttaatgaaa ataccattaa aaaatatcta caatgcacta
     4801 acatccagac agtgacgatg cctgttcctg cgaagttttt acgtgcttca aatgtaccga
     4861 ctggattgct taatgaaatg attgcttatc tcaactcgga agaacgcaat catcataatt
     4921 tttcagaact tttgcttttt tcttgcctgt ctatttttgc cgcatgcaaa ggtttcatta
     4981 cactattaac taacggtgtg ctatccgttt ccgggaaagt gagaaatatt gtcaacatga
     5041 agctggcgca cccatggaag ctgaaagata tttgtgactg cctgtacatc agtgaaagcc
     5101 tgttgaagaa aaaactaaag caagagcaaa cgacattctc acagattcta ttagatgcca
     5161 gaatgcagca cgcaaaaaat ttgatacgcg tagaaggttc agtcaataaa attgccgaac
     5221 aatgtggtta tgccagtaca tcttatttta tttatgcgtt ccgcaaacat ttcggcaaca
     5281 gtccgaagag agtttctaag gagtaccgtt gtcaaagtca catgggtatg aatacgggca
     5341 acacgatgaa tgctttagct atttgattat ttgctaacga gtagtcaacc acgcacccta
     5401 cgtaaaaatt aaaaatgggg cagtcattcc ctgccccgcg ttgtttttag gtgatatatt
     5461 tattgaaata aataagtgac attcatcaca tatttatgca tttgcataac ctgttgcatg
     5521 attatttatg atctcaattc ggcattttgt cagtaaaatg caataattta ttaaatatca
     5581 atagattagt tgtttatcgg caagaaatta cttagtagaa cagaaagtaa tgtcaacgct
     5641 ttatggactg ttatttccct ttttttagct aaatctgcta tctctttatg tgactaactt
     5701 cacttacacc cacttatttc tcttcgtaaa attacttcgg aattaagtac aataagaaga
     5761 ggaacattta tgaagtctgc attaaagaaa agtgtcgtaa gtacctcgat atctttgata
     5821 ctggcatctg gtatggctgc atttgctgct catgcggcag atgatgtaaa gctgaaagca
     5881 accaaaacaa acgttgcttt ctcagacttt acgccgactg aatacagtac caaaggaaag
     5941 ccaaatatta tcgtactaac catggatgat cttggttatg gacaacttcc ttttgataag
     6001 ggatcttttg acccaaaaac aatggaaaat cgtgaagttg tcgataccta caaaataggg
     6061 atagataaag ccattgaagc tgcacaaaaa tcaacgccga cgctcctttc attaatggat
     6121 gaaggcgtac ggtttactaa cggctatgtg gcacacggtg tttccggccc ctcccgtgcc
     6181 gcaataatga ccggtcgagc tcccgcccgc tttggtgtct attccaatac cgatgctcag
     6241 gatggtattc cgctaacaga aactttcttg cctgaattat tccagaatca tggttattac
     6301 actgcagcag taggtaaatg gcacttgtca aaaatcagta atgtgccggt accggaagat
     6361 aaacaaacgc gtgactatca tgacaacttc accacatttt ctgcggaaga atggcaacct
     6421 caaaaccgtg gctttgatta ctttatggga ttccacgctg caggaacggc atattacaac
     6481 tccccttcac tgttcaaaaa tcgtgaacgt gtccccgcaa aaggttatat cagcgatcag
     6541 ttaaccgatg aggcaattgg cgttgttgat cgtgccaaaa cacttgacca gccttttatg
     6601 ctttacctgg cttataatgc tccgcacctg ccaaatgata atcctgcacc ggatcaatat
     6661 cagaagcaat ttaataccgg tagtcaaaca gcagataact actacgcttc cgtttattct
     6721 gttgatcagg gtgtaaaacg cattctcgaa caactgaaga aaaacggaca gtatgacaat
     6781 acaattattc tctttacctc cgataatggt gcggttatcg atggtcctct gccgctgaac
     6841 ggggcgcaaa aaggctataa gagtcagacc tatcctggcg gtactcacac cccaatgttt
     6901 atgtggtgga aaggaaaact tcaacccggt aattatgaca agctgatttc cgcaatggat
     6961 ttctacccga cagctcttga tgcagccgat atcagcattc caaaagacct taagctggat
     7021 ggcgtttcct tgctgccctg gttgcaagat aagaaacaag gcgagccaca taaaaatctg
     7081 acctggataa cctcttattc tcactggttt gacgaggaaa atattccatt ctgggataat
     7141 taccacaaat ttgttcgcca tcagtcagac gattacccgc ataaccccaa cactgaggac
     7201 ttaagccaat tctcttatac ggtgagaaat aacgattatt cgcttgtcta tacagtagaa
     7261 aacaatcagt taggtctcta caaactgacg gatctacagc aaaaagataa ccttgccgcc
     7321 gccaatccgc aggtcgttaa agagatgcaa ggcgtggtaa gagagtttat cgacagcagc
     7381 cagccaccgc ttagcgaggt aaatcaggag aagtttaaca atatcaagaa agcactaagc
     7441 gaagcgaaat aactaaacct tcatgcggcg gaattttccg ccgccttatt gagcgagata
     7501 gcgatgcacg ttacagccaa gccctccagt tttcaatgta atctcaaatg tgattactgt
     7561 ttttaccttg aaaaagagtc gcagtttact catgaaaaat ggatggatga cagtactctg
     7621 aaagagttca tcaaacaata tatcgcagcg tctggcaatc aggtctattt tacctggcaa
     7681 ggcggtgaac ccactctggc tggcctggat tttttccgta aagttattca ctatcaacaa
     7741 cgctatgcag gccaaaaacg tatttttaat gcattacaaa cgaatggcat tttattgaat
     7801 aatgaatggt gtgcctttct caaagaacat gaatttctgg ttggtatctc gatcgatggc
     7861 ccccaggagt tacatgaccg ttacagacgc agtaattcag gtaacggtac ttttgcaaaa
     7921 gtgatagcag ccatcgagcg tctgaaatca tatcaagttg agtttaatac gttaaccgtc
     7981 attaataacg ttaatgtcca ttaccctctt gaggtttatc attttttaaa atctatcggc
     8041 agtaaacata tgcaatttat cgaattgctc gaaaccggga cgccgaatat tgatttcagt
     8101 ggtcatagtg agaacacatt ccgtatcatt gatttttctg tgcctcccac ggcttatggc
     8161 aagtttatgt caaccatttt tatgcaatgg gttaaaaacg atgtgggtga aattttcatt
     8221 cgtcagtttg aaagctttgt cagccgtttt ttggggaatg ggcatacaag ttgtattttc
     8281 caggagtcct gcaaggataa tctggttgtt gaaagtaatg gagacattta cgaatgcgac
     8341 cattttgtct atccacagta caaaattgga aacattaata aatctgaact caaaacgatg
     8401 aacagtgtac aactgacagc gcaaaaaaaa cggatttcag cgaaatgtca gcaatgtgca
     8461 tataaaccta tctgcaatgg cggttgtcct aagcatcgta ttactaaagt aaacaatgag
     8521 actgtttctt atttttgcga aggttataaa atcctttttt caaccatggt accttatatg
     8581 aacgccatgg tggagttagc taagaacaga gtaccgcttt accacattat ggatgttgca
     8641 aaacaaatgg agaataatta ataacgctct cttttaactc cattcttagc ctccttctta
     8701 tgaccttaac aaggcacccg acataaattc ctgtcgggtg tttcgtcatc atcatcttcc
     8761 cttgcgaaaa tcctggctta cgtggtatgc gtcagggcat tagcaatacc cttgattatc
     8821 aatagcataa ccataaccac tgaaaatgaa atattccttt atatttcata ttgttaaatg
     8881 atacttaaat aaatttcatc agtaaatcat tgccatagat aatcattgga tggcacaatc
     8941 aattttcgct aatgataacc attcccatta cgttttgtat gttgatagca aagtatctct
     9001 gtctgctgaa gcccttttgg ctgcgtaaga ataataaaac ttcagtgttg ttaatcatta
     9061 ttatcctcgc catgatcctt ggcgtggtta aaattcaggt ctggttaaac gactggaata
     9121 atgatttttt caatgcgcta agccagaaag aaaccgataa gctttggcag cttgtccttt
     9181 ggttccctgc cctgctgggg atctttgtat taatatccgt aaacaaaaca tggttaatta
     9241 aactactgac tattcgctgg cgcgaatggt taacagatta ctaccttaat cggtggtttg
     9301 cagataaaaa ctactacttc acgcagatct acggcgagca taaaaataca gataaccctg
     9361 accaacgtat cgctgaagac attctcttac tgatcagcaa aacgctcagc ctttcatttg
     9421 gcttcatcca gtcacttagc atgctgatca cctttaccgt tattctttgg caaagcgcgg
     9481 gtacgctctc attcactgtt ggtggaacag aatggaatat ccaggggtat atggtctata
     9541 ccgttgtgct cattgtgatc ggtggaactt tatttaccca taaggttggt aaacgtattc
     9601 gtccgcttaa tgtggaaaaa caacgtagcg aagcgacatt tcgaacaaat cttgtgcagc
     9661 ataataagca ggcagaactg attgcgctaa gcaatgctga gtctctacaa cgccaggagt
     9721 tgagcgacaa ttttcatacc attaaagaga actggcatcg tttaatgaat cgtcagcggt
     9781 ggcttgatta ctggcagaat atttattcgc gctcgcttag cgttcttccc tactttctgt
     9841 tattgccgca gtttattagc gggcagatca atctgggcgg actgatgaaa tcgcgccagg
     9901 catttatgct ggtatcgaac aatttaagct ggtttattta taaatatgac gaacttgctg
     9961 agctggctgc ggttatcgat cgcttgtatg agttccatca actcactgaa cagcgcccta
    10021 cgaataagcc taaaaattgc caacatgcgg tacaagtggc taatgcgagt attcgtacgc
    10081 ctgataataa gatcatatta gagaacttga actttcatgt ttcgccaggc aaatggctat
    10141 tactgaaagg ctactctggt gcgggaaaaa ccacactgct taaaacatta tcccactgct
    10201 ggccgtggtt taaaggtgat atttcttctc ctgctgacag ttggtatgtg tcacaaacac
    10261 cgttaatcaa aagcggctta ctgaaagaga ttatttgtaa agcacttccc ctgcccgtag
    10321 acgataaatc gttgagcgaa gtactgcatc aggttggtct ggggaaattg gctgcgcgta
    10381 ttcatgacca cgatcgctgg ggagatattc tttccagcgg cgaaaaacaa cgtatcgccc
    10441 tggcacgatt aattttacga cgtccgaaat ggatatttct tgacgaaact acctctcatc
    10501 ttgaggaaca agaggctatc cgcttactgc gtttagtgcg tgaaaaacta cccacaagcg
    10561 gcgtcattat ggttacacat caacccggtg tctggaacct ggcagatgat atttgtgaca
    10621 ttagcgcggt tttataaaaa caataaaagc cctgctgtac ggagatataa ataaatgaag
    10681 cgagttctta ttcctggcgt cattttatgt ggcgctgatg tggcgcaggc cgtcgatgac
    10741 aaaaacatgt acatgcatgt ttttgaagag atgacggtct atgctcctgt ccctgtaccc
    10801 gtaaacggca acacgcatta caccagtgaa agcatcgagc gtttaccgac cgggaatggc
    10861 aatatcagcg atctgctgag aaccaaccct gcggtacgca tggattcaac gcaaagtacc
    10921 tcgttgaacc agggagatat tcgcccggag aaaatctcta ttcacggtgc gtcgccctat
    10981 cagaatgcct atttgattga cggtattagt gccactaata acttgaaccc agcgaatgag
    11041 tccgatgcca gtagtgcaac caatattagc gggatgtcac aggggtatta tcttgatgtc
    11101 agcttactgg acaatgtgac gctttatgac agttttgtgc cggttgaatt cggtcgcttc
    11161 aatggcgggg taattgatgc aaagatcaaa cgcttcaacg ctgatgatag cagcgtgaaa
    11221 ctgggttatc gcactacgcg ttcggactgg ttaacatcgc atatcgatga gaataacaag
    11281 agcgcattta atcaaggctc ttcaggaagt acttattact ccccagattt taaaaagaac
    11341 ttttatacct tgtcgtttaa tcaggaactc gctgataact ttggcgttac cgccggttta
    11401 tcgcgccgcc agtctgatat cacccgcgcg gattatgttt cgaatgacgg cattgtcgcc
    11461 ggtcgggcac agtataaaaa cgttatcgat accgcattga gcaaatttac ctggtttgcc
    11521 agcgaccgct ttacccacga tttaacctta aaatataccg gctccagccg tgattataat
    11581 accagcacct tcccgcagtc tgatcgcgaa atgggtaata aatcctatgg tctggcatgg
    11641 gatatggata cgcagctcgc atgggccaaa ctacgtacca ccgttggttg ggatcatatt
    11701 agtgattata cccgtcacga tcatgacatc tggtacaccg aactttcatg tacatatggt
    11761 gatattacag ggcgttgcac ccgtggcgga ttaggacaca tttcccaggc tgtagataat
    11821 tacaccttca aaacacgcct ggactggcaa aaattcgccg tgggtaatgt ttcgcatcaa
    11881 ccctacttcg gcgcggaata catctattcc gatgcgtgga ctgaacgcca taaccagtct
    11941 gaatcctatg tgattaatgc tgccggaaag aaaactaacc ataccattta ccataaaggt
    12001 aaaggcagcc tgggaattga caactacacg ctgtatatgg cggatcgcat tagctggcgt
    12061 aatgtgtcat taatgcccgg cgtgcggtat gactatgaca actatctgtc aaaccacaat
    12121 atctccccgc gctttatgac ggaatgggat atttttgcta atcaaacctc aatgattaca
    12181 gcaggttata accgttacta tggcgggaat attcttgata tgggattacg tgatatccgc
    12241 aatagctgga cggaatcggt atcaggtaat aaaactctga cgcgttatca ggatttgaaa
    12301 acgccttata acgatgaact ggcaatggga ttgcagcaga aaatcggtaa gaacgttatt
    12361 gcgcgtgcaa actatgttta ccgtgaagcg catgatcaaa taagcaaaag cagtcgtacc
    12421 gacagcgcga ctaaaaccac cattactgaa tataacaacg atggcaaaac caaaacgcat
    12481 tcgttcagcc tcagttttga actggccgaa cccctgcata tccgccaggt agatattaac
    12541 ccacaaattg tctttagcta tatcaagagc aagggcaact tgtcgttaaa caatggttat
    12601 gaggagagca ataccggtga taaccaggtg gtttataacg gtaatctggt ctcttacgat
    12661 agcgttccag tggcagattt taataaccca ttaaagatct ccttaaacat ggatttcacg
    12721 catcaaccga gcgggttagt gtgggcgaat acgctggcct ggcaagaagc gcgtaaagct
    12781 cgcattatcc tgggtaagac aaatgcgcaa tacatcagcg aatattcaga ttacaagcag
    12841 tatgttgacg aaaaactgga tagcagcctg acctgggaca cccgcttgtc ctggacgcca
    12901 caatttctga aacaacaaaa cctgacgatc agtgccgata ttctcaatgt attggatagc
    12961 aaaaccgctg ttgatacaac gaataccggt gtggcgacct acgccagtgg ccgtactttc
    13021 tggcttgatg tcagcatgaa attttaatag ttcggatttt acttaaccgg gtaaattcgc
    13081 ccggttttcg catggagata attatgagaa acctctgttt cttactgacg ttagtggcaa
    13141 ctctgttgct ccccgggcgg ctgattgccg ccgccttacc gcaggatgaa aagttaatta
    13201 ccgggcaact gggcaatggc ttgcgatata tgatttatcc gcatgctcat ccaaaggatc
    13261 aggtaaattt atggctgcaa attcataccg gttcattgca ggaagaagac aatgagcgcg
    13321 gcgtagctca ttttgtagaa catatgatgt ttaacggcac aaaaacatgg ccgggtaata
    13381 aagtcatcga aacatttgag tcaatgggcc tgcgttttgg tcgcgatgtt aatgcctata
    13441 ccagctatga cgaaacggtg tatcaggtga gtttgccgac tacgcagaaa caaaatctgc
    13501 aacaagtgat ggcaatcttc agtgaatgga gtaatgccgc aacctttgaa aaactcgaag
    13561 tagacgctga acgtggcgta attactgagg aatggcgtgc ccatcaggat gcgaaatggc
    13621 gcacctctca ggcgcgccgc cctttcctgc tggctaatac ccgtaattta gaccgtgaac
    13681 ctatcggcct gatggatact gtcgccacgg tcacaccggc acaattgcgc caattttatc
    13741 aacgctggta tcaaccaaat aatatgacct ttatcgtggt cggcgatatc gacagtaaag
    13801 aagcgctggc gctgataaag gataatttaa gtaagcttcc ggctaacaaa gcagctgaaa
    13861 atcgcgtctg gccgacaaaa gccgaaaacc acctgcgctt taatatcatt aatgataaag
    13921 aaaaccgggt gaacggcatc gcactctatt atcgcctgcc aatggtacaa gtgaacgatg
    13981 agcaaagctt tatcgaacaa gctgaatgga gcatgttagt tcagctgttc aatcaacgtc
    14041 tgcaggaacg catacagtcg ggcgagttga agactatttc tggcggcact gcgcgcagcg
    14101 ttaaaattgc acccgattat cagtcgctgt ttttccgtgt aaatgcacga gacgataata
    14161 tgcaggatgc tgcgaatgca ttaatggcag agttggcaac cattgatcag catggttttt
    14221 ctgctgaaga actcgatgat gtcaaatcta cccgcctcac ctggctgaaa aatgcggttg
    14281 atcagcaagc tgaacgtgat ttacgtatgc tgaccagtcg cctggcatcc agctcattaa
    14341 ataatacgcc gttcttgtcg ccggaagaga catatcaact ttcgaaacgt ctgtggcagc
    14401 aaattaccgt gcaaagtctg gcggaaaaat ggcagcagtt aagaaagaac caggacgcat
    14461 tttgggagca aatggtaaac aatgagcttg ccgccaaaaa agcattgtct cctgcggcta
    14521 tcctggcgct ggaaaaagag tacgccaaca aaaagctggc ggcttacatc ttcccaggca
    14581 gaaatttatc gttaacagta gacgctgacc cacaggcgga aattagcagc aaagaaacgc
    14641 tggctgagaa tctgacatca ttaacacttt ccaatggtgc cagggttatt ctggcaaaat
    14701 ccgcgggtga agagcaaaag ctacaaatta ctgccgtatc gaataaaggc gatttaagtt
    14761 tccctgcgca gcaaaaatca cttatcgcgc tggcaaataa agcagtaagc ggaagcggcg
    14821 ttggtgagct ctcctcttcc agcctgaaac gctggagtgc ggaaaattcg gtaaccatga
    14881 gcagtaaagt cagtggcatg aatacgttgc tctccgttag cgcgcggact aataaccctg
    14941 aacctggttt tcagttgatt aaccagcgaa tcacccacag cacgattaac gacaatattt
    15001 gggcatcgct acaaaatgct caaattcagg cgttgaaaac gctcgaccag cgtccagcgg
    15061 agaaattcgc ccagcagatg tttgagacgc gctatgctga tgaccgcacg aaattactgc
    15121 aagaaaatca gattgtacag tttactgccg cagatgcgct ggctgccgat cgccagttgt
    15181 tttcatctcc agcggatatc acgtttgtca ttgtcggtaa tgtctcagaa gacaaactcg
    15241 tggcgttaat tacgcgttac ttaggatcaa tcaaacactc tgattcgcca ttagccgcag
    15301 gtaaaccatt aactcgcacg acggacaacg catcggttac tgtaaaagaa caaaatgaac
    15361 ctgtggcaca ggtttcacag tggaagcgtt atgattcccg gacacctgtt aatctggcga
    15421 cgcgtatggc gctcgatgct tttaacgtcg cactggcaaa agatctacgt gttaatattc
    15481 gtgaacaggc atctggagca tacagcgttt cttctcgcct ctcggttgat cctcaggcca
    15541 aagatatcag tcatttgctg gcttttactt gtcaaccaga acgacatgat gaactgttaa
    15601 cgttagcgaa tgaagtgatg gttaagcgtc tggctaaagg gatcagtgag caagaactga
    15661 atgaatacca gcaaaacgtt cagcgcagcc tcgatatcca acagcgtagc gttcaacaat
    15721 tagcgaacac tattgtaaat agtcttattc aatatgacga tcctgcagca tggactgagc
    15781 aggagcaatt gttgaaacaa atgacggtag agaatgttaa cactgccgtt aaacaatatc
    15841 tttcttatcc ggtaaatact tataccggag tattattgcc aaaataata
//
LOCUS       DAZUDJ010000091        15765 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.091, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000091 DAZUDJ010000000
VERSION     DAZUDJ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15765
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.091"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..99
                     /locus_tag="ACHY1N_004248"
     CDS             <1..99
                     /locus_tag="ACHY1N_004248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415678.1"
                     /note="interacts RssB preventing the degradation of the
                     stress sigma factor RpoS; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HFS4046454.1"
                     /translation="KSSQECPPGERKITNKCLHNSCIIKICPYGLK"
     gene            complement(202..1452)
                     /gene="icd"
                     /locus_tag="ACHY1N_004249"
     CDS             complement(202..1452)
                     /gene="icd"
                     /locus_tag="ACHY1N_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004450 - isocitrate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HFS4046455.1"
                     /translation="MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     ANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIV
                     IKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYD
                     FERLMEGAKLLKCSEFGDAIIKNM"
     gene            1624..2277
                     /gene="rluE"
                     /locus_tag="ACHY1N_004250"
     CDS             1624..2277
                     /gene="rluE"
                     /locus_tag="ACHY1N_004250"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415653.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HFS4046456.1"
                     /translation="MRQFIISENTMQKTSFRNHQVKRFSSQRSTRRKPENQPTRVILF
                     NKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPG
                     KRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER
                     KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWREVTD"
     gene            2287..2748
                     /gene="nudJ"
                     /locus_tag="ACHY1N_004251"
     CDS             2287..2748
                     /gene="nudJ"
                     /locus_tag="ACHY1N_004251"
                     /EC_number="3.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase NudJ"
                     /protein_id="HFS4046457.1"
                     /translation="MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETL
                     VEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDID
                     CCRWVSAEEILKASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI"
     gene            2802..3908
                     /gene="mnmA"
                     /locus_tag="ACHY1N_004252"
                     /gene_synonym="trmU"
     CDS             2802..3908
                     /gene="mnmA"
                     /locus_tag="ACHY1N_004252"
                     /gene_synonym="trmU"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415651.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004808 - tRNA
                     (5-methylaminomethyl-2-thiouridylate)(34)-
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0002143 - tRNA wobble position uridine
                     thiolation [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFS4046458.1"
                     /translation="MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFD
                     EPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV"
     gene            3944..4585
                     /gene="hflD"
                     /locus_tag="ACHY1N_004253"
     CDS             3944..4585
                     /gene="hflD"
                     /locus_tag="ACHY1N_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HFS4046459.1"
                     /translation="MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSII
                     DMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL"
     gene            4589..5959
                     /gene="purB"
                     /locus_tag="ACHY1N_004254"
     CDS             4589..5959
                     /gene="purB"
                     /locus_tag="ACHY1N_004254"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0006188 - IMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFS4046460.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADAIGYLDAIVANFSEEDAARIKTIERTTNHDVKAVEYFLKE
                     KVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQ
                     YRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAIT
                     MVDELK"
     gene            6127..6798
                     /gene="phoP"
                     /locus_tag="ACHY1N_004255"
     CDS             6127..6798
                     /gene="phoP"
                     /locus_tag="ACHY1N_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HFS4046461.1"
                     /translation="MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHL
                     PDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGY
                     LFELR"
     gene            6798..8258
                     /gene="phoQ"
                     /locus_tag="ACHY1N_004256"
     CDS             6798..8258
                     /gene="phoQ"
                     /locus_tag="ACHY1N_004256"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HFS4046462.1"
                     /translation="MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDV
                     PWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVA
                     VNVYPATSRMPKLTFVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSL
                     RPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLS
                     RELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACK
                     YCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAR
                     EITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE"
     gene            8334..9455
                     /gene="roxA"
                     /locus_tag="ACHY1N_004257"
                     /gene_synonym="ycfD"
     CDS             8334..9455
                     /gene="roxA"
                     /locus_tag="ACHY1N_004257"
                     /gene_synonym="ycfD"
                     /EC_number="1.14.11.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415646.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[50S ribosomal protein L16]-arginine
                     3-hydroxylase"
                     /protein_id="HFS4046463.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLA
                     MESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRE
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYV
                     LQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGEVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALD
                     ALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(9601..10830)
                     /gene="pepT"
                     /locus_tag="ACHY1N_004258"
     CDS             complement(9601..10830)
                     /gene="pepT"
                     /locus_tag="ACHY1N_004258"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFS4046464.1"
                     /translation="MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEE
                     MGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNI
                     PHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVDRADMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHIID
                     IAQQAMRDCNIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTAQRKS"
     gene            11080..12216
                     /gene="potA"
                     /locus_tag="ACHY1N_004259"
     CDS             11080..12216
                     /gene="potA"
                     /locus_tag="ACHY1N_004259"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HFS4046465.1"
                     /translation="MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGREC
                     NIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK"
     gene            12200..13063
                     /gene="potB"
                     /locus_tag="ACHY1N_004260"
     CDS             12200..13063
                     /gene="potB"
                     /locus_tag="ACHY1N_004260"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309597.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HFS4046466.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASR
                     LLNKKATEIDN"
     gene            13426..14787
                     /gene="espK"
                     /locus_tag="ACHY1N_004261"
     CDS             13426..14787
                     /gene="espK"
                     /locus_tag="ACHY1N_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector EspK"
                     /protein_id="HFS4046467.1"
                     /translation="MLPTSQLRPSGTFYSNSAETSAGIKSEITPTQIEEARAIGRLYI
                     KDCDIEYLPQLPNEITSVTIENCNNLTTLTGLPVNTQNLSVINCEKLQITDIPSTVKN
                     LHIELTDSPFIHIISEGIECLTVCHCHISGVPESVRHLEIRGYATDGIKNVPNGLLSL
                     SINRYTPENQARIDSLISPSLQTLSLTGCSNIILPEKLPESLRSVTIHVEQKTTWNIV
                     AEGVPDGLDLDLQNVLLSPNVIKEKNITFQGNALDAALHFRPGDIVYGLSSPREKLVN
                     SIKLVNDFSKKDIVIQNTLTNAVWDARTPRKYKQDSLIKRALNEHERGTKFKQCLKNH
                     NNYNVIMADLSIYNRDKLWAKTSKAGLEFQTLIRNRTVMFCADGLVNSLKLIANKSEG
                     YGQSITASELRWIYRNKDNSQIMKNIKFYLHGKEIPAERILDTPEWKDYRPKYSGSTY
                     KYS"
     gene            complement(15164..>15765)
                     /locus_tag="ACHY1N_004262"
     CDS             complement(15164..>15765)
                     /locus_tag="ACHY1N_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4765 family protein"
                     /protein_id="HFS4046468.1"
                     /translation="YKSEGLHGGGVIRYIDKPYSQLREGDIGYDEDLLDIYDDSPVLE
                     DTLPALSSEIVPTPEHSIKQIYSKIKEGHIELSDSDIILCRGTTGIQAENIVEYKTAG
                     GLPDSNPNVKAPDEYMAQQQVRIGRILPEYTSDLSVADRFSREHYLIVVKVKAKYITR
                     GSVTESGWVIDKTAPVEPLAIIDRTFGMKENISMVNASK"
BASE COUNT         4093 a         3898 c         3789 g         3985 t
ORIGIN      
        1 aaaagcagtc aagagtgtcc tccaggagaa agaaaaataa caaataaatg tttgcataat
       61 agttgcatta taaaaatatg cccatatggg ctcaagtaaa gggttttata taaatatgct
      121 cgatatgcta ttaataatac ctacataaat aaaacaacgg gcgtgttata cgcccgttgc
      181 aatattaaac acatgtagtg attacatgtt cttgatgatc gcatcaccaa attctgaaca
      241 tttcagcagt ttagcgcctt ccatcagacg ctcgaagtca taggttacgg tcttcgcatt
      301 gattgcgcct tccatacctt taacaatcag gtctgcggct tcagtccagc ccatatggcg
      361 taacatcatc tcagcggaga gaataataga gccagggttt actttgtcct gaccggcgta
      421 tttcggcgca gtaccgtggg tggcttcaaa cagggcgcat tcgtcaccga tgtttgcacc
      481 aggggcgata ccgataccgc caacctgcgc tgccagggcg tcagaaatgt agtcaccgtt
      541 caggttcata caggcgataa catcatattc agccggacgc agcaggatct gttgcaggaa
      601 tgcatcagca atcacgtctt taatgacgat ctctttgccg gtgttcgggt ttttaacttt
      661 cagccacggg ccgccgtcga tcagttcacc gccaaactct tcacgcgcca gctggtagcc
      721 ccagtcttta aacgcgcctt cggtgaactt catgatgttg cctttgtgca ccagggtcac
      781 agagtcacgg tcgttggcaa ttgcgtattc aatcgcggca cggaccagac gtttggtgcc
      841 ttcttcagaa cacggcttga taccgatacc gcaatgttcc gggaagcgaa ttttcttcac
      901 gcccatctct tcacgcagga atttaatcac tttctcggcg tcggcagagt ctgctttcca
      961 ttcgataccc gcataaatgt cttccgagtt ttcacggaag ataaccatat cggtcagttc
     1021 agggtgttta accgggcttg gagtgccttg atagtaacgt accggacgca ggcagatgta
     1081 gagatccagt tcctggcgca gggcaacgtt cagagagcga ataccgccac caacaggagt
     1141 ggtcagcgga cctttaatag caacgcgata ttcacgaatc agatcaaggg tttcagcagg
     1201 cagccagaca tcctgaccat aaacctgtgt ggatttttca ccggtgtaaa tttccatcca
     1261 ggagatttta cgctcgcctt tataggcttt ctcgactgca gcgtcgacca ctttcagcat
     1321 ggctggggtt acatctacac cgattccatc accttcaatg taagggataa tcggattttc
     1381 aggaacgttg agtttgccgt tttgcagggt gatcttcttg ccttgtgccg gaacaactac
     1441 tttactttcc attcacctct ccttcgagcg ctactggttt gctcgtctgc caccacgttg
     1501 catatgcgtt tgcgtcctgc gatacggatg ctttagagca attttttgtt aatgatttgt
     1561 aattggcttg tcaatactac cctattgttt gccgtcatga aagatgcgcg ttattaggct
     1621 ataatgcggc aattcataat ctctgaaaat accatgcaaa aaacttcttt tagaaatcac
     1681 caggttaagc gattcagctc gcaacgttct accaggcgta aacctgaaaa ccagcccacg
     1741 cgtgtgatcc tgttcaataa accctacgat gttcttccgc agttcaccga tgaagccgga
     1801 cgcaaaacat taaaagaatt catcccggtt cagggcgttt atgcagcagg tcgtcttgac
     1861 cgcgatagcg aagggttact ggtgctgacc aataacggcg cgttgcaggc gcgtttaacc
     1921 cagccgggta aacgcaccgg gaaaatctat tatgtgcagg tggaaggtat tcccacacaa
     1981 gacgcacttg aagccttgcg caatggcgta accttaaatg atggccctac cctgcccgcc
     2041 ggcgcggagc tggttgacga accagcgtgg ttatggccgc ggaatccacc aattcgtgaa
     2101 cgcaaaagta ttcccaccag ctggctgaag atcaccttat atgaaggacg taatcgccag
     2161 gtgcgccgca tgaccgccca tgttggtttc cccacgctgc gactgattcg ctatgcgatg
     2221 ggagattact ctttggataa tcttgccaat ggcgaatggc gagaagtgac agattaagga
     2281 tgcaaaatgt ttaaaccgca cgttaccgtt gcttgcgtgg tgcacgcaga aggcaaattt
     2341 ttagtcgttg aagagacgat taatggtaaa gcgttatgga accaacctgc cgggcatctg
     2401 gaagccgatg aaaccttagt ggaagccgcc gcccgtgaac tgtgggaaga aaccggcatc
     2461 agcgcgcagc cgcaacactt tattcgtatg catcagtgga ttgcgccaga taaaacgccg
     2521 tttttgcgtt tcctctttgc cattgagctt gagcaaatat gcccgaccca gcctcatgac
     2581 agcgatatcg actgctgtcg ttgggtcagc gccgaagaga ttttaaaggc gtcaaatctt
     2641 cgttcgccgc tggtggcgga aagtatccgt tgttatcaaa gcgggcaacg ctatccgctg
     2701 gagatgattg gcgattttaa ctggcctttt acaaagggtg tcatctaaaa ggctgcgtga
     2761 tagaatacgc cgccttgaag ttcaatgtcg tgagtgatcc aatgtctgaa accgcaaaaa
     2821 aagtaatcgt cggcatgtcc ggcggtgtcg attcctccgt ttctgcctgg ctgttgcaac
     2881 aacagggata tcaggttgaa ggcctgttta tgaagaactg ggaagaagac gacggtgagg
     2941 aatattgcac agcggcagcg gatctggctg atgcccaggc tgtctgcgac aagctcggca
     3001 ttgaactgca caccgttaac tttgctgccg agtactggga caacgtcttc gaactgttcc
     3061 ttgccgaata taaagccggt cgcacgccga atccggatat tctgtgcaac aaagagatca
     3121 aatttaaagc cttcctcgaa tttgccgccg aagatttagg tgccgattat atcgctaccg
     3181 gtcattacgt acgtcgggcc gatgtcgatg gcaagagccg cctgctgcgt ggtctggaca
     3241 gcaataaaga ccagagctac ttcctttata cgctcagcca tgagcagatt gcgcaaagcc
     3301 tgttcccggt cggcgaactg gaaaaaccgc aggtgcgtaa gattgctgaa gatcttggtc
     3361 tggtcaccgc gaagaaaaaa gactctaccg gcatttgctt cattggcgaa cgtaaattcc
     3421 gcgagttcct gggccgttat ctcccggcgc aaccgggcaa aatcattacc gtcgatggcg
     3481 atgaaattgg tgagcaccag gggctgatgt atcacactct cggtcagcgt aaaggtctgg
     3541 gtatcggtgg caccaaagaa ggtaccgaag aaccgtggta tgtggtggac aaagacgtcg
     3601 aaaacaacat tctggttgtc gctcagggcc atgaacaccc gcggctgatg tctgtcgggt
     3661 tgattgccca gcagttgcac tgggtcgatc gcgaaccatt caccggcact atgcgttgca
     3721 cggtaaaaac ccgctatcgc cagaccgata tcccttgcac cgtcaaggcg ctggacgatg
     3781 atcgcattga agtgattttc gatgaaccgg ttgccgccgt gacgccgggc cagtctgccg
     3841 tcttctataa cggtgaagtg tgcctcggtg gcggtattat tgagcagcgt ctgccgctgc
     3901 cggtctgatt attatcttta cttaaaacaa ggaagcagtg aacgtggcaa agaattacta
     3961 tgacatcacc ctcgccctgg ccggtatttg tcagtcggca cgcctagtgc aacaactcgc
     4021 tcaccagggg cattgtgatg ccgatgcgct acacgtctca ctcaacagta ttattgatat
     4081 gaaccccagc tcgacgctgg cggtttttgg cggtagcgaa gccaacctgc gcgtcgggct
     4141 ggaaaccctg ctcggcgtgc tcaatgccag cagtcgccag ggcttaaacg ccgaattaac
     4201 ccgctacaca ctcagcttga tggtgcttga gcgcaaactc tcctcagcga aaggcgcgct
     4261 cgacactctg ggcaaccgga tcaacggcct gcaacgccag ctcgaacact tcgatttaca
     4321 gtccgaaacg ctgatgagcg cgatggctgc tatctatgtt gatgtgatca gcccgcttgg
     4381 cccgcgcatt caggtcaccg gttcccctgc tgtactgcaa agcccacaag tgcaggcgaa
     4441 agttcgcgca accctgctgg caggcattcg cgccgccgtg ctctggcacc aggtcggcgg
     4501 cggacgtctg caactgatgt tttctcgtaa tcgcctgacc actcaggcaa aacaaattct
     4561 tgctcattta accccggagt tgtgatctat ggaattatcc tcactgaccg ccgtttcccc
     4621 tgtcgatgga cgctacggcg ataaagtcag cgcgctgcgc gggattttca gcgaatatgg
     4681 tttgctgaaa ttccgtgtac aagttgaagt acgttggctg caaaaactgg ccgcgcacgc
     4741 agcgatcaag gaagttcctg cttttgctgc cgacgcaatc ggttaccttg atgcaattgt
     4801 cgccaatttc agcgaagaag atgccgcacg catcaaaacc atcgagcgta ccactaacca
     4861 cgacgttaaa gcggttgagt atttcctgaa agaaaaagtg gcggagatcc cggaactgca
     4921 cgcggtttct gaattcatcc actttgcctg tacttcggaa gatatcaata acctctccca
     4981 cgcattaatg ctgaaaaccg cgcgtgatga agtgatcctg ccgtactggc gtcaactgat
     5041 tgatggcatt aaagatctcg ccgttcagta ccgcgatatc ccgctgctgt ctcgtaccca
     5101 cggtcagcca gccacgccgt caaccatcgg taaagagatg gcaaacgtcg cctaccgtat
     5161 ggagcgccag taccgccagc ttaatcaggt ggagatcctc ggcaaaatca acggcgcggt
     5221 cggtaactat aacgcccata tcgccgctta cccggaagtt gactggcatc agttcagcga
     5281 agagttcgtc acctcgctgg gtattcagtg gaacccgtac accacccaga tcgaaccgca
     5341 cgactacatt gccgaattgt ttgattgcgt tgcgcgcttc aacaccattc tgatcgactt
     5401 tgaccgtgac gtctggggtt atatcgccct taaccacttc aaacagaaaa ccattgctgg
     5461 tgagattggt tcttccacca tgccgcataa agttaacccg attgacttcg aaaactccga
     5521 agggaatctg ggcctttcca acgcggtatt gcagcatctg gcaagcaaac tgccggtttc
     5581 ccgctggcag cgtgacctga ccgactccac cgtgctgcgt aacctcggcg tgggtatcgg
     5641 ttatgcgctg attgcgtatc aatccaccct gaaaggcgtg agcaaactgg aagtaaaccg
     5701 tgaccatctg ctggatgagc tggatcacaa ctgggaagtg ctggctgagc caatccagac
     5761 agttatgcgt cgctatggca tcgaaaaacc gtacgagaag ctgaaagagc tgactcgcgg
     5821 taagcgcgtt gacgccgaag gcatgaagca gtttatcgat ggtctggcgt tgccagaaga
     5881 agagaaagcc cgcctgaaag cgatgacgcc ggctaactat attggtcgag ctatcaccat
     5941 ggttgatgag ctgaaataaa ctcgtatcag tgccggatgg cgatgctgtc cggcctgttt
     6001 attaaaatta tccacttttt cttttttcac tttacctccc ctccccgctg gtttatttaa
     6061 tgtttacccc cataaacaca taatcgcgtt acactatttt aataattaag acagggagaa
     6121 ataaaaatgc gcgtactggt tgttgaagac aatgcgttgt tacgtcacca ccttaaagtt
     6181 cagattcagg atgctggtca tcaggtcgat gacgcagaag atgccaaaga agccgattat
     6241 tatctcaatg aacatttacc ggatattgcg attgtcgatc tcggattgcc tgacgaggac
     6301 ggtctgtcac tgattcgccg ctggcgtagc aatgatgttt cactgccgat tctggtatta
     6361 accgcccgtg aaagctggca ggacaaagtc gaagtattaa gtgccggtgc tgatgattac
     6421 gtgactaaac cgtttcatat tgaagaggtg atggcgcgaa tgcaggcatt aatgcggcgt
     6481 aatagcggcc tggcttcaca ggtcatttcg ctacccccgt ttcaggttga tctctctcgc
     6541 cgtgaattat ctattaatga cgaagtgatc aaactgaccg cgttcgaata caccattatg
     6601 gaaacgttga tacgcaataa tggcaaagtg gtgagcaaag attcgttaat gctccaactc
     6661 tatccggatg cggagctgcg ggaaagccat accattgatg tactgatggg acgtctgcgc
     6721 aaaaaaattc aggcacaata tccgcaagaa gtgattacta ccgttcgcgg ccagggctat
     6781 ttgttcgaat tgcgctgatg aaaaaattac tgcgtctttt tttcccgctc tcactgcggg
     6841 tacgttttct gttggcaacg gctgcggtag tactggtgct ttcgcttgcc tacggaatgg
     6901 tcgcgctgat cggttatagc gtcagtttcg ataaaactac gtttcggctg ttacgtggcg
     6961 agagcaatct gttctatacc cttgcgaagt gggaaaacaa taagttgcat gtcgagttac
     7021 ccgaaaatat cgacaagcaa agccccacca tgacgctaat ttatgatgag aacgggcagc
     7081 ttttatgggc gcaacgtgac gtgccctggc tgatgaagat gatccagcct gactggctga
     7141 aatcgaatgg ttttcatgaa attgaagcgg atgttaacga taccagcctc ttgctaagtg
     7201 gagatcattc gatacagcaa cagttgcagg aagtgcggga agatgatgac gacgcggaga
     7261 tgacccactc ggtggcagta aacgtctacc cggcaacatc gcggatgcca aaattaacct
     7321 ttgtggtggt ggataccatt ccggtggagc taaaaagttc ctatatggtc tggagctggt
     7381 ttatctatgt gctctcagcc aatctgctgt tagtgatccc gctgctgtgg gtcgccgcct
     7441 ggtggagttt acgccccatc gaagccctgg caaaagaagt ccgcgaacta gaagaacata
     7501 accgcgaatt gctcaatcca gccacaacgc gagaactgac cagtctggta cgaaacctga
     7561 accgattgtt aaaaagtgaa cgcgaacgtt acgacaaata ccgtacgacg ctcaccgacc
     7621 tgacccatag tctgaaaacg ccactggcgg tgctgcaaag tacgctgcgt tctctgcgta
     7681 gtgaaaagat gagcgtcagt gatgctgagc cggtaatgct ggagcaaatc agccgcattt
     7741 cacagcaaat tggctactac ctgcatcgtg ccagtatgcg cggcgggaca ttgctcagcc
     7801 gcgagctgca tccggtcgcc ccactgctgg acaatctcac ctcagcgctg aacaaagtgt
     7861 atcaacgcaa aggggtcaat atctctctcg atatttcgcc agagatcagc tttgtcggtg
     7921 agcagaacga ttttgtcgag gtgatgggca acgtgctgga taatgcctgt aaatattgcc
     7981 tcgagtttgt cgaaatttct gcaaggcaaa ccgacgagca tctctatatt gtggtcgagg
     8041 atgatggccc cggtattcca ttaagcaagc gagaggtcat tttcgaccgt ggtcaacggg
     8101 ttgatacttt acgccctggg caaggtgtag ggctggcggt agcccgcgaa atcaccgagc
     8161 aatatgaggg taaaatcgtc gccggagaga gcatgctggg cggtgcgcgg atggaggtga
     8221 tttttggtcg ccagcattct gcgccgaaag atgaataaat atgtccatac ttcacgcatt
     8281 acgttaagca tccgttataa tcggttgcag ataccagcct gtggatgctt aacatggaat
     8341 accaactcac tcttaactgg cccgattttc ttgaacgtca ctggcagaaa cgcccggtgg
     8401 tgttaaaacg cggctttaat aattttattg acccgatctc tccagacgag ttggcgggtc
     8461 tggcgatgga aagcgaagtt gacagtcgac tggtcagtca ccaggatggc aaatggcagg
     8521 tcagccacgg cccgttcgaa agctacgatc atctcggtga aaccaactgg tcattactgg
     8581 tacaggcagt gaaccactgg catgagccga ccgccgcgct gatgcgaccg ttccgtgaac
     8641 taccggactg gcgtattgat gatctgatga tctctttttc tgtaccgggc ggcggcgtcg
     8701 gcccgcatct cgatcagtac gacgtgttta tcattcaggg taccggtcgt cgtcgctggc
     8761 gagtgggcga aaagctgcaa atgaaacagc actgtccgca cccggatctg ttacaggtcg
     8821 atccgttcga agccatcatc gatgaagagc tggagcctgg cgatattctt tatattccgc
     8881 caggattccc gcatgaaggc tacgcgctgg aaaatgcgat gaactattcc gtgggttttc
     8941 gcgcgccaaa tacgcgggaa ttaattagcg gatttgccga ttatgtgctg caacgtgaac
     9001 tgggcggcaa ctactacagc gatccggatg ttccacctcg cgctcatcct gcggacgttc
     9061 tgccgcaaga gatggataaa ctgcgtgaga tgatgctcga attgatcaac cagccggaac
     9121 actttaagca atggtttggc gagtttatat cccagtcacg tcatgaactg gatatcgcgc
     9181 cgccggaacc gccttatcag ccagatgaaa tctacgatgc gctgaaacaa ggtgaagtgc
     9241 tggtgcgcct gggtggtctg cgcgtattgc gcattggcga cgacgtgtat gccaatggtg
     9301 agaagatcga ttccccgcac cgtccggcac tggatgcact cgccagcaac attgcgctga
     9361 ctgcggagaa ttttggcgat gcgctggaag atccgtcatt cctcgcgatg ctcgcggcgc
     9421 tggtcaatag cgggtattgg ttcttcgaag ggtaagtttg gatttaagcc ggatgcggcg
     9481 ctgattgcgc cttatcgtgc ctacatgcac tgaacgcctg taggcacgat aagtatgttg
     9541 accagtatca atataacggt ttcatcccgg taattggcag tccacatacg catcgggcaa
     9601 tcacgacttc cgttgcgccg ttaactcggc aatacggaca atcacctgca ccgctttttc
     9661 cataccttcc agagtcacaa actcatgctt accatgatag ttgtaaccgc cagtgaacag
     9721 gttcgggcac ggtaatccca taaacgacaa ctgcgcgccg tcggtaccgc cgcggatcgg
     9781 tttcagttcc ggttcaatat tgcagtcacg catcgcctgc tgggcgatat cgataatatg
     9841 cggatgctca accactttct cgcgcatatt gtagtaactg tcttcaatca ccagttcaat
     9901 gtagcaatca ggatgtaacc ctttgcccac ttttttggcg atctccatca ttttacgttt
     9961 acgcgcttca aactgtttac ggtcgaaatc acggatgatg tagtgcatat cggctcggtc
    10021 aacggtgcct ttcatgctcg ccaggtgata gaaaccttca tagccttctg tcatttccgg
    10081 gctttcatcc gccggaactt ccgcatgaat acgtgccgcc agcgacagcg catttaccat
    10141 cactcctttc gccgtgcccg gatgaacatt gttaccgaca attttgatat tgaccgatgc
    10201 ggcgttgaag ttttcaaact ccagttcacc tacgccacca ccgtcaacag tgtaagccca
    10261 gcgggcatcg aaggcatcaa catcaaaatg tttcgcccct ttgcccactt cttcatccgg
    10321 ggtaaaggcg acgcgaatat caccatgcgg aatgtttttc tgttgcaata ccgccagcgc
    10381 ggtcatgatt tctgcaatac cggctttgtc atcggcacct aacaaggttt taccatcggt
    10441 agtaatcagc gtctgaccca gtagctgatg cagcaccggg aacataaccg gtgataaaac
    10501 ttcatcgccg atacccagcg caatatcgcc accgcgatag ttttcaacaa tttgcggatt
    10561 cacatttttg ccgctgcaat ccggtgaggt atccacatga gaaataaagc caatcgccgg
    10621 gatatcgcca gggacgttag ccggtaacgt cgccatcaaa gtgcccttct cacttaaggt
    10681 cacattgata agccccatct cttcgagctg ctctttcagc agatgcaata acttccattg
    10741 gccttccgtg ctgggaacct gtctcacccc tgcttttgat tgggtatcca gagacacgta
    10801 gttcaaaaat cgctcaagta gtttatccat gtagtcaccc tcactttttg tgacaacatt
    10861 attaagaagc aagaaaagac aaatattgcg tcaggtcact tttacccctg caagcgggaa
    10921 tatttatcag cattacctta atgaatataa agctaagcca gtaattcaca acaaagattg
    10981 gcgattcaag cggtttgccg tagaattacc gccctcatta agagtcacca aggtggttaa
    11041 ccacaaaccc cgcatcggta agccatccgt tgcgtttaca tgggacagag taaaaaattg
    11101 aataaacaac cgagttcgct ttcaccgctg gtgcaattgg cgggaattcg caaatgcttt
    11161 gatggtaaag aggtcattcc ccagctggat ctgactatca acaatggcga gttcctcacg
    11221 ctgcttggcc cttctggctg cggtaaaaca accgttcttc gcctgattgc aggtctggaa
    11281 actgttgatt ccggacgcat catgctggat aacgaggaca tcacccacgt tccggcggaa
    11341 aaccgctatg tgaacactgt tttccaaagc tacgcacttt tcccccacat gaccgtgttc
    11401 gaaaatgtgg cctttgggtt gcgcatgcaa aaaacccccg ctgctgaaat tacgccccgc
    11461 gtgatggaag ccctgcggat ggtgcaactg gaaaccttcg ctcaacgtaa accgcatcag
    11521 ctctctggtg gtcaacagca acgcgtcgcc attgcccgcg cggtggttaa caagcctcgt
    11581 ctgttgttgc tggatgagtc gctctcagcg ctggattaca aactgcgcaa gcaaatgcag
    11641 aacgagctga aagcgttaca gcgtaagctt ggcattacat tcgtcttcgt gactcacgac
    11701 caggaagaag cactcaccat gtcagacagg attgtggtga tgcgcgatgg tcgcattgag
    11761 caagacggca cgccgcgtga aatctacgaa gagccgaaaa acctgtttgt tgccgggttc
    11821 attggcgaaa ttaatatgtt taacgccacg gtgatcgagc gactcgacga gcagcgcgta
    11881 cgcgccaacg ttgaaggccg cgaatgtaat atctacgtta acttcgccgt tgaaccgggg
    11941 caaaaactgc atgttctgct gcgcccggaa gacttacgtg ttgaagagat taacgacgac
    12001 aaccacgctg aagggctgat tggttacgtt cgtgagcgta actacaaagg catgacgctg
    12061 gagtcggttg ttgaactgga aaatggcaag atggtgatgg tcagcgaatt cttcaatgaa
    12121 gacgaccctg actttgacca ctctctcgac caaaaaatgg ccattaattg ggtagaaagc
    12181 tgggaggtcg tactggctga tgaagaacac aagtaagttc cagaatgtag tgattgtcac
    12241 tattgtcggt tggcttgtgt tgtttgtctt tctgcccaac ctgatgatca ttggcaccag
    12301 ctttttgacc cgcgacgacg ccagtttcgt caaaatggtc tttacgctgg ataactacac
    12361 gcgtctgctc gatccgctct attttgaagt gctattgcac tcgctgaata tggcgctgat
    12421 cgccaccctc gcctgcctgg tgctgggcta cccgtttgcc tggtttctgg cgaagctgcc
    12481 acacaaggtg cgtccgctgc tgctgtttct gctgattgtt cccttctgga ccaactcatt
    12541 gattcgtatc tacgggctga aaattttcct cagcaccaaa ggctatctca acgagttttt
    12601 gctctggctg ggcgttatcg acacaccaat ccgtatcatg ttcacgccca gtgcggtgat
    12661 tatcggtctg gtttacattc tgctgccgtt tatggtgatg ccgctgtact ccagtatcga
    12721 aaaactggat aagcctttgc ttgaggcggc gcgcgatctc ggtgccagca agttgcagac
    12781 ctttatccgc atcattatcc cactgacgat gccggggatt attgccggat gtctgctggt
    12841 gatgctgcca gcgatgggcc tgttctatgt gtccgacctg atgggcggtg cgaaaaacct
    12901 gctgatcggt aacgtcatca aggtacagtt cctcaatatt cgtgactggc catttggtgc
    12961 agccaccagc attacgctga ctatcgtaat gggcctgatg ttgctggttt actggcgcgc
    13021 ttctcgtctg ctgaataaga aggcaacaga aatagataat tagtgcttta tattcaaaag
    13081 gttaatagca aatttggcat gctttttact gtctagtaaa cagcatgcct ctatccataa
    13141 aatcaaacag ttgcaatcta attttggaga acgttttttc ttctcccttt tagcaaatcg
    13201 ctataaaaaa caacaaatgg tataaaaatg agcaatccta atccatgcat gacggactgg
    13261 agaaagtatt cgcaaaagtt aaaatcaaca gtctgttgat tttgagatat aactctcttt
    13321 tctaatattg acaccttggc tttgctggtt gctaaaatta gcttgttgat tagcagtatg
    13381 gatagaactt acactgttat ttacttctaa aaatggaatt tatcaatgct tcctacatcg
    13441 caattacgac cgtccgggac attctactcc aattccgcag aaacatcagc aggcatcaaa
    13501 agcgaaatca caccaactca gatagaagaa gcgcgggcca ttggtcgttt atatatcaaa
    13561 gattgtgata ttgagtatct gccacagtta ccaaacgaaa taacatcagt tacaatcgaa
    13621 aattgcaata acctgaccac ccttacagga ttaccggtta atacacaaaa cctgtccgtc
    13681 attaactgtg aaaaattaca aatcacagac ataccatcga cagtaaaaaa tctacatatt
    13741 gaattaactg attcaccatt tatacacatc atatctgaag gcatcgaatg cctgacggtt
    13801 tgccactgcc atatatctgg agtgccagag agtgtccgtc atcttgagat cagaggttac
    13861 gccacagacg gcataaaaaa tgttccaaac gggttattat ctctcagcat caatcgctac
    13921 accccagaaa atcaggccag aattgacagc ctgatatcac cgtcactaca gacgctatct
    13981 ctgactggat gtagcaatat tatactgccg gagaaactcc cggagagtct gagatctgta
    14041 accattcatg tggagcagaa aactacatgg aacatcgtag ctgaaggggt tcctgatgga
    14101 ctggatcttg atttacaaaa tgtactactc tctccgaatg taattaaaga aaaaaacatc
    14161 acttttcagg gcaacgcact ggatgctgcc ttgcattttc gtccgggaga cattgtctat
    14221 gggctatcct ctcccagaga aaaacttgtc aacagcatca aactggttaa cgacttttcc
    14281 aaaaaagata tcgtaattca gaatacatta acaaacgcag tatgggacgc cagaaccccc
    14341 cgtaaatata agcaagactc gcttatcaaa agagcattaa atgaacatga aagaggaaca
    14401 aaatttaaac agtgcttaaa aaatcacaat aattataatg tcatcatggc cgacctttcc
    14461 atatacaatc gagacaagtt atgggcaaaa acaagcaagg caggcctaga gtttcaaaca
    14521 ttaattcgca acagaacggt tatgttttgt gcggatgggc ttgtcaattc actcaaactc
    14581 atagctaaca agtcagaggg ctatggtcag agtattaccg ccagcgaatt acgatggatt
    14641 tatcgtaata aagacaacag ccaaataatg aaaaacataa aattttatct gcatggcaaa
    14701 gagataccag cagaaagaat attagataca ccagagtgga aagactaccg tccaaaatac
    14761 tccggttcca catataaata ttcttaatga tagcaaaaaa tatattttcg atataatcaa
    14821 tgttatgatt aaagagtatt tcatcagggc aggtaaaaac agagtaaatc agcaaaagaa
    14881 gctgatcttc agcgatactg acactaactg acggtttaag cggtcgtatg aagcagcagc
    14941 tttccgacgg actgccatgc ggatcgttta ccttttgggc tattccgccc gtcatcaagc
    15001 ggctcacgag tactgagttt atcaggatga tattgctgac aatggtaatt cgttgaccga
    15061 tgtgtacttc actatatatc ggtcaacacc gtactgccgt gcaacatctc aaagatgtag
    15121 catcgttttt accagaggag gcaggacata gattgtaaaa aaactatttc gatgcattta
    15181 ccattgagat attttccttc ataccaaaag ttctatcaat tatcgcaagt ggttcaacag
    15241 gtgcggtctt atctataacc caaccactct ctgtaacact tcctcgtgtg atatattttg
    15301 cctttacttt aacaactatt agataatgct cacgactaaa ccgatcagca acgctaagat
    15361 ccgatgtgta ttcaggcaat attcttccaa tacgtacctg ctgttgtgcc atatattcat
    15421 ctggtgcttt tacatttgga tttgaatcag gaagccctcc agcagtttta tattcaacga
    15481 tattttcagc ttgaataccg gttgtgccgc gacacaatat gatgtctgaa tcggacagtt
    15541 ctatgtgccc ctccttaatt ttcgaataaa tttgtttaat actatgttct ggagttggta
    15601 ctatttcaga agataaagca ggcaacgtgt cttcaagcac cggagaatca tcgtatatat
    15661 ccaacaaatc ctcatcatac ccaatatctc cttctcttaa ctgagaatac ggtttatcta
    15721 tgtatctaat aactccccca ccatgaagac cttctgattt ataaa
//
LOCUS       DAZUDJ010000092        15328 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.092, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000092 DAZUDJ010000000
VERSION     DAZUDJ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15328
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.092"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(180..1091)
                     /gene="gsiD"
                     /locus_tag="ACHY1N_004263"
     CDS             complement(180..1091)
                     /gene="gsiD"
                     /locus_tag="ACHY1N_004263"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HFS4046469.1"
                     /translation="MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAA
                     LFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPA
                     LAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            complement(1094..2014)
                     /gene="gsiC"
                     /locus_tag="ACHY1N_004264"
     CDS             complement(1094..2014)
                     /gene="gsiC"
                     /locus_tag="ACHY1N_004264"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HFS4046470.1"
                     /translation="MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEAD
                     AQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLT
                     ITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELG
                     WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQA
                     EILLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            complement(2032..3570)
                     /gene="gsiB"
                     /locus_tag="ACHY1N_004265"
     CDS             complement(2032..3570)
                     /gene="gsiB"
                     /locus_tag="ACHY1N_004265"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0034634 - glutathione transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034775 - glutathione transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HFS4046471.1"
                     /translation="MARAVHRSGLVALGIATALMASCAFAAKDVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGLTYTVKLREGIKFQDGT
                     DFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAH
                     PATAMISPAALEKYGKEIGFHPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSI
                     TWRPVADNNTRAAMLQTGEAQFAFPIPYEQATLLEKNKNIELMASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPVKA
                     RELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEV
                     EGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQ
                     ALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFED
                     ADLQ"
     gene            complement(3590..5461)
                     /gene="gsiA"
                     /locus_tag="ACHY1N_004266"
     CDS             complement(3590..5461)
                     /gene="gsiA"
                     /locus_tag="ACHY1N_004266"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter ATP-binding protein
                     GsiA"
                     /protein_id="HFS4046472.1"
                     /translation="MPHSDELDAGNVLAVENLNIAFMQDQQKIAAVRNLSFSLQRGET
                     LAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLQRRSREVIELSEQSAAQMRHVR
                     GADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQT
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEM
                     SMGVIFITHDMGVVAEIADRVLVMYQGEAVETGTVEQIFHAPQHPYTRALLAAVPQLG
                     AMKGLDYPRRFPLISLEHPAKQAPPIEQKTVVDGEPVLRVRNLVTRFPLRSGLLNRVT
                     REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLS
                     PGKLQALRRDIQFIFQDPYASLDPRQTIGDSIIEPLRVHGLLPGKDAAARVAWLLERV
                     GLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLD
                     LQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAA
                     VPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR"
     gene            complement(5448..6413)
                     /gene="iaaA"
                     /locus_tag="ACHY1N_004267"
     CDS             complement(5448..6413)
                     /gene="iaaA"
                     /locus_tag="ACHY1N_004267"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFS4046473.1"
                     /translation="MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLE
                     AGESALDVVTEAVRLLEECPLFNAGIGAVFTRDETHELDACVMDGNTLKAGAVAGVSH
                     LRNPVLAARLVMEQSPHVMMIGEGAENFAFARGMERVSPEIFSTPLRYEQLLAARKEG
                     ATVLDHSGAPLDEKQKMGTVGAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGC
                     YANNASVAVSCTGTGEVFIRALAAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGG
                     LIAIDHEGNVALPFNTEGMYRAWGYAGDTPTTGIYREKGDTVATQ"
     gene            6617..7852
                     /gene="moeA"
                     /locus_tag="ACHY1N_004268"
     CDS             6617..7852
                     /gene="moeA"
                     /locus_tag="ACHY1N_004268"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0032324 - molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HFS4046474.1"
                     /translation="MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASNV
                     VSPLDVPGFDNSAMDGYAVRLADIASRQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGA
                     PVPEGCEAVVMQEQTEQTDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAE
                     LPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGC
                     EVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVR
                     TASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGN
                     VDVGEWVEVEPFNALFGGL"
     gene            7852..8601
                     /gene="moeB"
                     /locus_tag="ACHY1N_004269"
     CDS             7852..8601
                     /gene="moeB"
                     /locus_tag="ACHY1N_004269"
                     /EC_number="2.7.7.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HFS4046475.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLVVGLGGLGC
                     AASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDAMTRINPHIA
                     ITPVNALLDDAELAAMIAKHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQ
                     ITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKLLAGYGKP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(8677..9339)
                     /gene="fsa"
                     /locus_tag="ACHY1N_004270"
     CDS             complement(8677..9339)
                     /gene="fsa"
                     /locus_tag="ACHY1N_004270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFS4046476.1"
                     /translation="MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAAGKKPLDVVLP
                     QLHEAMGGQGRLFAQVMATTAEGMVNDARKLRSIIADIVVKVPVTAEGLAAIKMLKAE
                     GIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQA
                     KVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVEAAVAKFEQDWLGAFGRT
                     SI"
     gene            9470..10369
                     /gene="ybiY"
                     /locus_tag="ACHY1N_004271"
     CDS             9470..10369
                     /gene="ybiY"
                     /locus_tag="ACHY1N_004271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415345.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HFS4046477.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDL
                     LYDARLCLEGCELCAKAAPEVIERALNGLLIHREKLTPEHLTALTDCCPTQALTVCGE
                     VKSVEEIMTTVLRDKPFYDRSGGGLTLSGGEPFMQPEMAMALLQASHEAGIHTAVETC
                     LHVPWKYIAPSLPYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLAAAGKKIIIR
                     MPLIQGFNADETSVKAITDFAADELHVGEIHFLPYHTLGINKYHLLNLPYDAPEKPLD
                     APELLDFAQQYACQKGLTATLRG"
     gene            10375..12807
                     /gene="ybiW"
                     /locus_tag="ACHY1N_004272"
     CDS             10375..12807
                     /gene="ybiW"
                     /locus_tag="ACHY1N_004272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HFS4046478.1"
                     /translation="MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDGLREKVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSE
                     HIERFAALAREMAATETRESRRDELLTMAENCDLIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDT
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQK
                     LMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            12953..13768
                     /gene="ybiV"
                     /locus_tag="ACHY1N_004273"
     CDS             12953..13768
                     /gene="ybiV"
                     /locus_tag="ACHY1N_004273"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase YbiV"
                     /protein_id="HFS4046479.1"
                     /translation="MSVKVIVTDMDGTFLNDAKTYNQPHFMAQYQELKKRGIKFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLQSAYVSENAPEAFVALMAKHYHRLKAVKDYQEIDDVLFKFSLNLPDEQIPL
                     VIDKLHIALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGN
                     DAEMLKMARYSFAMGNAAENIKQIARYATDDNNHEGALNVIQAVLDNTSPFNS"
     gene            13920..15185
                     /gene="ybiU"
                     /locus_tag="ACHY1N_004274"
     CDS             13920..15185
                     /gene="ybiU"
                     /locus_tag="ACHY1N_004274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1479 domain-containing protein"
                     /protein_id="HFS4046480.1"
                     /translation="MASTFTSDTLPADHKAAIRQMKHALRAQLGDVQQIFNQLSDDIA
                     TRVAEINALKAQGDAVWPVLSYADIKAGHVTAEQREQIKRRGCAVIKGHFPREQALGW
                     DQSMLDYLDRNRFDEVYKGPGDNFFGTLSASRPEIYPIYWSQAQMQARQSEEMANAQS
                     FLNRLWTFESDGKQWFNPDVSVIYPDRIRRRPPGTTSKGLGAHTDSGALERWLLPAYQ
                     RVFANVFNGNLAQYDPWHAAHRTEVEEYTVDNTTKCSVFRTFQGWTALSDMLPGQGLL
                     HVVPIPEAMAYVLLRPLLDDVPEDELCGVAPGRVLPVSEQWHPLLIEALTSIPKLEAG
                     DSVWWHCDVIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYAHKVKAALEKGASPGDFP
                     REDYETNWEGRFTLADLNIHGKRALGMDV"
BASE COUNT         3710 a         4237 c         3905 g         3476 t
ORIGIN      
        1 atgttaatac atttaacaaa ataactatct gaacgctgtg ccgctgcaaa aatagtccct
       61 tgctgcggct ttttaaccaa attacccgat tctacaaaat cagcagaaag ttacaacact
      121 tgcttagggc aataatttcc tgtgaggtga ttaccctttc acgcaatatt caaacgtaac
      181 tatcctttaa ttttcggatc cagcgcatcg cgtaaaccat cgcccaacaa attgaacgcc
      241 agtacggtca gaaaaatagc cagggccgga aaaacagcga catgcggcgc gataaccata
      301 tccgctcgtg cctcattgag cattgctccc cactctggtg tcggcggctg cgcaccgagg
      361 ccgagaaatg acaggctggc ggcagagata atcgaggtgc caatgcgcat ggtgaaaaac
      421 accacgatag acgagacggt cccaggcaag atatgacgca ataaaatggt catatcgctg
      481 gcaccaatac tgcgtgctga ctcaataaag gtttgctgtt tcaacaccag cgtgttgccg
      541 cgcaccagtc gggcaaacgc ggggatggaa aaaatggcga ctgcgataat cacgttagca
      601 atgccgcttc ccaacaccgc aacaacagcg atcgccagta aaatacccgg gaaggcaaac
      661 agcacatcgc aaatgcgcat gatcaaccga tcccaccagc cttcataata tccagccaac
      721 aagcccagca acgtcccgat cgccgcaccg ataaacacgg caaacacgcc cgccgccagc
      781 gagatttgcg caccaaccag gacacggctg aaaatgtcgc gccccagtga atcgacgcca
      841 aaccagtgct gcaaagaagg tccgttattc aggttgtcat aatcaaaata attttcggcg
      901 tcatagggag cgatccagcg tgcaaaaatg gccaccacaa tcaataaaat aacgaataat
      961 gcggcggtca tcgccatatg ctgacggcga aatcgtcgcc agaattcatg ccacggtgta
     1021 cgcacctggt caggtttgac cagtggcatg gcgtttaaca ccgcctgacg tcgccagtta
     1081 aatagtcgca tccttacttg tacctgatag ccgggttaat ggcggcgtaa agcacatcca
     1141 ccactaagtt gataagaata aattccagcg agaaaagcag aatttccgcc tgaatcaccg
     1201 ggtaatcgcg catttctacg gagtcaacga gtaagcgtcc aagtccgggc cagttgaaaa
     1261 ctttctccac cacgatagat ccaccgagca aaaagccaaa ctgtaagccc atcatggtca
     1321 ctaccgggat catcgcgttg cgtagcccgt gtttgaggac aacccaggtt tcgctcaccc
     1381 ctttcgccct cgcggtacgc atataatctt cgcttaaaac gtcgacaaat gacgcacggg
     1441 taaagcgcgc catcacggcg gccactgccg cgccgagcgt cagggagggt aaaatgtagt
     1501 gctgccaact gtctgctccc acagtaggca gccagcccag ttcaacggag aatacctgaa
     1561 ttaaaagcat ccccagagca aatgccggaa acgagatccc cgacaccgca atggtcatac
     1621 tcaatcgatc cggccaacgg ttacgccaga cggcggcgat aattcccgcc gccataccaa
     1681 atatcaccgc ccagaccata ctggttatgg tcagccacag cgttggcata aagcggctgg
     1741 caatctcatc ggcaactgga cgacgcgaca ccatggacag gccaaaatcc ccctgcacag
     1801 cattgctgat atagtgccag aactggtgat acagcggctg atccaacccc agctgctgac
     1861 gcaccagttc tataacctgc gcatcagctt cgggcccggc aatcaatcgc gccggatcgc
     1921 cgggcagcat atggacaaat aaaaacacca gcaccgagac gataaacagc gtcggaatca
     1981 accccagtaa tcgtttgata acgtaattaa gcattccact ccctgcgttg cttattgcaa
     2041 atccgcatct tcaaagctga agccggtgtc tggcatgatc caaaaaccgg tcaggttttt
     2101 actgtgtgcc gacaccagtt tttctaccac cagcgggatc cacggcgact cttgccagat
     2161 gatatcctgc gccgccttat ataaacgggt cttttccgcc ggatcattag ttttcagtgc
     2221 ctgagccagg aagtcatcca cctgtttatt gctgtaaaac gcggtattaa acagcgtcgg
     2281 tggccagttt tgcgaggcaa acaacggcga tagtgcccag tcggcttcgc cggttgaagc
     2341 cgaccagcca gtgtagaaca tccgcacgcc gctctctttt tgccctttac cttcaacttc
     2401 tgccgcccgc tgtccggcat ccatcgcagt cacctgggct ttaatcccga cctgcgctaa
     2461 ctgctgctgg gtaaattgca gcactttctg cgcggtgctg tggttatgtg acgaccacag
     2521 cgtggtactg aaaccgttgg gatatcccgc ctctttcagt aattcgcgcg ctttcactgg
     2581 atcgtaaggc cacggtttat aactttgcgc gtaggcgata cttggcggta ccacaccagt
     2641 agctggcgtt gcatagcccg caaaggcaac tttcaccagc gccggacggt taatggcgta
     2701 attcagcgcc tcacggacct tcgggttatc gaacggcttt tgcgtcacgt tcatactgat
     2761 ataacgctgc ataattgacg gactggccat caactcgata tttttgtttt tctccagcag
     2821 tgtggcctgc tcgtagggaa tggggaaagc aaactgcgct tcaccggttt gcagcattgc
     2881 cgcgcgggtg ttgttatccg ccaccggacg ccaggttatg ctgtccagtt tgggcaatcc
     2941 tggctgccag taacccgcga attttttcac cttcacaaaa tcggtctgat tccaggtatc
     3001 cagttcatac ggtccggttc ccaccggatg aaaaccaatc tccttgccat atttttccag
     3061 cgctgccggt gaaatcatcg cggtcgccgg atgggcaaga atattaataa acgctgagaa
     3121 cggctgtttg agagtaatct ttactgttgt tggatcgatc gcctccgttt tggcaatatt
     3181 cttatacagg ttatagcgtt taagatgatt cgccggatcg ctggcccggt ccagattcgc
     3241 ttttaccgcc gctgcgttga aatcggtgcc atcctggaat ttaattcctt cccgcaattt
     3301 cacggtgtat gtaaggccgt catcggaaac ggtataactc tccgccagca cgtttttcag
     3361 tttcatctct ttatccagac caaacagccc ctggtaaaac gatttcgcta cggcctgaga
     3421 taacgtgtca tttgcgtcat acggatcgag cgtggtgaag ttcgatccta ccgccaccac
     3481 cacatctttg gcagcgaatg cacaagatgc catcaacgct gtcgcaatgc ccaacgccac
     3541 taacccacta cggtgtacag ctcttgccat tttattctcc gcctgaatgt tatctacgca
     3601 tgaatgcgta ttctgattgt ggttgtgcga cgtaatgccc cggcccgacg cattgcaacg
     3661 agacggctgc cacctcttcg ccacgcagat gaatattgct gggaagatcg tccgacagca
     3721 gtacacgctg cggtcgttgt cgggacggtt cagcgaccgg aactgccgcc agtaatttac
     3781 gcgtataagg atgctgcggg ttttcgaaga ccgcgcgccg tggaccaatt tcaacaattt
     3841 gtccgagata catcaccgcc acacgatgac taatccgctc taccacggcc atatcgtggg
     3901 agataaacag atacgcaatg ccgaaatcac gctggagatc gagcaacaag ttgataatct
     3961 gcccgcgaat agaaacatcc agcgccgaaa cggcttcgtc ggcaatgatc acttttggat
     4021 tcaatgccaa cgcgcgagca atgcagatgc gctggcgctg accgccggaa aactcatgcg
     4081 ggtaacgcca ggcatgttca ggtaacaggc ccacgcgctc cagcaaccac gcaacgcgtg
     4141 cagccgcgtc tttacctggc aataaaccgt gtacacgcag cggttcgata atcgaatcac
     4201 cgatggtctg acgtgggtcc agcgaagcgt aagggtcctg aaaaataaac tgaatatccc
     4261 ggcgcaatgc ctgaagtttg ccgggtgaca aggtatcgat tctctgaccg ttaaagataa
     4321 tttcgccgcc ctgcgattcg accaggcgca gcaacgcccg cccggtagtg gatttaccgc
     4381 tgccagactc gcccaccagc gatagcgttt cgccaggcca gagatcaaaa ctgactttct
     4441 caacggcatg cacttcccgc gttacgcgat tcaacaaacc gctgcgcaaa gggaaacggg
     4501 tgacaagatt acgcactcgt aaaacaggtt cgccatccac caccgttttc tgctcgatgg
     4561 ggggggcctg tttcgctgga tgttcaagcg atatcaacgg gaaacgtcgg ggataatcta
     4621 accctttcat cgcaccaagt tgcggaacag cagctaacag cgcacgggtg taaggatgtt
     4681 gcggtgcatg aaaaatctgt tcgacggtac ccgtttccac cgcctcgccc tgatacatca
     4741 ccagtacccg atcggcaatc tctgccacca cgcccatatc gtgagtgata aagataacgc
     4801 ccatcgacat ctctttttgc aatactttga ttaattgcag gatctgcgcc tgaatagtga
     4861 catccagcgc ggtggttggc tcatcggcaa tcagcaccgc cgggcggcat gacagcgcca
     4921 tcgcaatcat cactcgctgg cgcatcccgc cagagagttg atgcggataa cgtgaaagaa
     4981 tggtttgtgc ctcaggaatg cgtacctgat ccagcatccg cttcgcctcg accatcgctt
     5041 cttcacgact ggcgttctga tgcagacgaa ttgattcggc aatctgttca cccacagtaa
     5101 ataccgggtt cagcgatgtc atcggctcct gaaatatcat cgccatatcc gcaccgcgaa
     5161 catggcgcat ttgtgcagcg ctctgctcgc taagttcaat cacttcgcga ctgcgccgct
     5221 gcaacagcat tttatcgcac tgtactaaac cgcccgcctg ttccaacagg cgcatcaatg
     5281 ccaacgcagt cactgactta ccggagccgg attcgccaac aattgccagc gtctcaccgc
     5341 gttgcagact aaaagagaga ttgcggaccg cagctatttt ctgctggtcc tgcataaagg
     5401 caatattcag attttcaacc gccagcacat taccggcatc aagttcatca ctgtgtggca
     5461 acggtgtccc ctttttcacg gtagataccg gtggttggcg tatcgcctgc gtagccccag
     5521 gcgcgataca ttccttcggt gttaaacggt agcgcgacat tcccttcatg gtcgatagcg
     5581 attaagccac cgctaccgcc aagcgcaggg agtttttcca ttactacccg ctcgcaggct
     5641 tccgcgagac ttaatccgcc gtaatccatt aacgcggcga tgtcatatgc cgccagcgcg
     5701 cggatgaaga cttcgcccgt gccggtacaa gaaaccgcca cactggcgtt attggcgtag
     5761 catccggcac ccactaaggg actatcgcca actcgtccgg gtaatttatt ggtcattccg
     5821 cctgtggacg tggctgccgc caaattgccg tctaaatcca acgccacggc ccccacggtg
     5881 cccattttct gtttttcatc cagtggcgca ccgctatggt cgaggacggt tgccccttcc
     5941 ttgcgcgctg ccagtagttg ttcataacgc aaaggcgtgg agaaaatctc cggcgagacg
     6001 cgctccatgc cacgagcaaa cgcaaaattt tctgcccctt cgccaatcat catcacatgc
     6061 gggctttgct ccatcaccag ccgggcggca agaaccggat tacgcagatg actaacgccc
     6121 gccaccgcac cggctttcag ggtgttacca tccatcacac aggcgtccag ttcatgggtt
     6181 tcatcacgcg taaagacagc gccaattccg gcgttaaaca gtggacactc ttccagcaaa
     6241 cgcaccgctt ccgtcaccac atccagcgca ctttcgcccg cttccagcat tttctgcccg
     6301 gtttcaacaa tggcagacaa cgcctcaatg tagcgtaatt cctgttgcag actcatctgc
     6361 gcgcggctaa ttgcacctgc gccaccatga attgcaatga ctgctttgcc catagtattc
     6421 gtccattaat ggtggctcgc cacttttgct ataaatatca gaatttttat gaattactca
     6481 ttcaattttt gaatatagaa agatggatat ggcatgtaaa ggcaggagcc aacgctacgc
     6541 ccgaggtggc atacagtctg tggcgttttt ctgacataat aggcaaattc gattttgcct
     6601 ccgcaggagt gttttcatgg aatttaccac cggattgatg tcgctcgaca ccgcgcttaa
     6661 tgagatgctt tctcgcgtca ccccactgac cgcccaggaa acgctgccac tggtacagtg
     6721 ttttggtcgt attctggcga gcaatgtcgt ttcgccgctt gatgttccgg ggtttgataa
     6781 ctccgcaatg gacggctacg cggtgcgttt agccgatatt gcctccaggc aaccgctgcc
     6841 cgttgccggt aaatcctttg ccggtcagcc gtaccatggt gaatggcctg cgggcacctg
     6901 cattcgtatt atgaccggtg cgccggtgcc ggaaggctgc gaagcggtgg tgatgcagga
     6961 gcagactgaa caaacggaca atggcgtgcg ttttactgct gaagtgcgta gcgggcaaaa
     7021 tattcgccgt cgcggtgaag atatctctgc aggtgcggtt gttttcccgg cgggaactcg
     7081 cctgactacc gcagagctgc cagtaattgc ttcactgggg attgccgaag ttccggtgat
     7141 tcgtaaagtg cgtgtagcgc ttttttctac cggtgatgaa ctccagttgc ccggtcagcc
     7201 gctgggcgac ggccaaatct acgacaccaa ccgtctcgcc gtacacctga tgttagaaca
     7261 gctgggttgc gaggtaatca acttagggat tatccgcgac gatccccatg ccctgcgcgc
     7321 cgcatttatt gaagccgaca gccaggcgga tgtagtgatc agttccggcg gtgtttcagt
     7381 gggtgaagcg gattacacca aaacgattct tgaagagctg ggggagatcg ccttctggaa
     7441 gctggcgatt aaaccaggta aaccgttcgc gttcggtaaa ctcagcaata gctggttctg
     7501 cggcctgccg ggcaacccgg tttcagcgac gctgaccttc tatcaactgg tacagccttt
     7561 gctggcaaaa ctaagcggca acaccgccag cggcctgccc gcgcgccagc gcgtacgcac
     7621 agcgtcccgc ctgaaaaaaa cgccaggacg tcttgatttc cagcgcggcg tgctgcaacg
     7681 caacgccgac ggtgaacttg aagtgacgac caccggacat cagggttcac atatatttag
     7741 ctcctttagt ctcggcaact gctttatcgt gctggaacgc gatcgcggca atgtggacgt
     7801 gggcgaatgg gtggaagtag aaccgtttaa cgcgttgttc ggaggcctgt aatggcggaa
     7861 ctcagcgatc aggagatgct gcgctacaac cggcaaatca ttctgcgcgg ttttgatttt
     7921 gacggtcagg aggcgctaaa agattctcgt gtgctggtag tcggcctcgg tggactcggc
     7981 tgcgcagctt cgcagtatct ggcaagcgcc ggtgtcggca acctgacgct gctcgacttc
     8041 gacacggttt cgctctcgaa tctgcaacgc cagacgctgc acagtgatgc tacggtcggg
     8101 caaccgaagg tagaatccgc ccgtgacgcc atgacgcgga tcaacccaca tatcgcgatt
     8161 acgccagtca atgcactgct tgatgacgct gaacttgctg cgatgattgc aaaacacgat
     8221 ctggtactcg actgtacgga taacgttgcg gtgcgtaatc aactgaacgc tggctgtttt
     8281 gccgcgaagg tgccgctggt ttccggcgcg gcaattcgta tggaagggca aatcacggtc
     8341 ttcacttatc aggacggcga accgtgctat cgctgcctta gccgtttgtt tggcgagaac
     8401 gcattaacct gcgtagaagc aggcgtgatg gcaccgttga tcggcgtaat tggttcgttg
     8461 caggcaatgg aagcgatcaa actgctggca ggttatggca aaccggccag cgggaaaatc
     8521 gtcatgtacg atgcgatgac ctgtcagttt cgcgaaatga aactgatgcg caatccgggg
     8581 tgtgaggtgt gcgggcagta attgccacct ccaggccaga taagacgcgg cactccgcca
     8641 cgtcatcagc aatttatgag gatgcagaac gtccggttaa atcgacgttc tgccaaacgc
     8701 tcccagccag tcctgttcaa acttcgccac agcggcttcc accgccggat agctaatcat
     8761 ctgttgtgcc acatccagtg gcagcgtaat tgattcacat cctgccagta agcagtccag
     8821 cgcctgacgc ggggttttga aactcgctgc cagcactttc gcctgcggcg catgcatttt
     8881 caataactgg tgtaagtcgg tcacagtctg aatgccgcta ccgccctgag catcaatacg
     8941 attaacgtaa ggcgcaacat attccgcacc tgccagcgcc gacagcagcc cttgtgctgc
     9001 gccatatacc gcggttccca gcgttggaat cccttccgct tttaacatct taatagctgc
     9061 cagcccctcg gcggtcaccg gaactttcac cacgatatcc gcaataatag aacgcaattt
     9121 acgtgcgtca ttcaccatcc cttcagcagt ggtagccatt acctgggcaa acagacgccc
     9181 ctgaccgccc atcgcttcat gaagttgcgg aagcacaaca tccagcggtt ttttacccgc
     9241 ggcgataatg cttgggttag tggtcacacc cgccagcgga aaaatacgtg acagcgcctt
     9301 caccgcaaca acgtctgaag tatccagata cagttccata accatcctca aaatgtactt
     9361 tttgtctgaa tgtagactat cacgggaaaa ctctctgaac agttgacgca catcaatcta
     9421 actttcattc gaaagtattt taatgtttga acgaaacaga gaggcaacta tgattttcaa
     9481 tattcagcgc tactcgaccc atgatggccc cggtatccgc acggtcgtat ttcttaaagg
     9541 ctgttcgctg ggctgccgct ggtgtcagaa cccggaaagc cgcgcccgca cgcaggatct
     9601 gctgtatgac gcacgactgt gtctggaagg ctgcgagctg tgcgctaagg ccgcgccgga
     9661 agtgattgag cgcgcgctga atggtttgct tattcatcgg gaaaagttaa ccccggagca
     9721 tctgacggcg ttaaccgact gctgtccgac acaggcatta accgtgtgtg gtgaagtgaa
     9781 aagcgttgag gagatcatga cgaccgttct gcgcgataaa ccgttttacg atcgcagcgg
     9841 cggcggttta acgctttcgg gtggtgagcc ctttatgcag ccggaaatgg cgatggcgct
     9901 actgcaagcc agccacgagg caggcattca tactgcggta gaaacctgtc tgcatgtgcc
     9961 gtggaaatat atcgcccctt ctctgcccta tatcgatctg tttcttgccg atttaaaaca
    10021 cgttgccgac gcgccgttta aacagtggac cgacggtaac gccgccagag tgctggataa
    10081 cctgaaaaaa ctcgccgcag cgggcaaaaa aatcattatc cgcatgccgc tgattcaggg
    10141 ctttaatgcc gacgaaacct ctgtaaaagc cattaccgat tttgccgccg acgagctgca
    10201 cgttggcgaa attcattttc tgccctacca cacgctgggc atcaacaaat atcacttact
    10261 taatctgccc tatgacgccc cggaaaaacc gcttgatgcg ccagaactgc tcgactttgc
    10321 ccagcagtat gcctgccaga aagggttaac cgcgacctta cgaggataac aaccatgacc
    10381 acactgaaac tggacacgct cagcgaccgc attaaagcgc acaaaaatgc gctggtgcat
    10441 attgtgaaac cgccagtctg taccgagcgc gcgcagcact ataccgagat gtatcaacaa
    10501 catctcgata agccgatccc ggtacgtcgc gcgctggcac tggcgcatca cctggcgaat
    10561 cgcaccatct ggatcaaaca cgatgagttg atcattggca accaggcaag cgaagttcgc
    10621 gccgcgccga tcttcccgga atatactgtc tcgtggatcg aaaaagagat tgatgatctg
    10681 gcagatcgtc ccggtgctgg ctttgcggtg agcgaagaga acaaacgcgt tctgcatgaa
    10741 gtgtgcccgt ggtggcgcgg tcagaccgta caggatcgct gctacggcat gtttaccgat
    10801 gagcaaaaag gtctgctggc gaccggaatc attaaagcgg aaggcaatat gacctccggc
    10861 gatgcgcacc tggcggtgaa tttcccgctg ctgctggaaa aaggtcttga tggtctgcgt
    10921 gagaaagtag cggaacgtcg ctcgcgcatc aatctgacgg tgctggaaga tttacatggc
    10981 gaacaattcc tgaaagcgat tgatatcgtg ctggtggcag tcagtgaaca cattgaacgt
    11041 ttcgctgccc tggcgcgtga aatggctgct accgaaactc gcgaaagccg tcgcgatgaa
    11101 ctgctgacga tggcagaaaa ctgcgatctt atcgcccacc agccgccgca gactttctgg
    11161 caggcgctgc aactgtgtta cttcatccaa ttgattttgc agatcgaatc taacggtcac
    11221 tcggtatcgt ttggtcgtat ggaccagtat ctctacccgt actatcgccg cgacgttgaa
    11281 ctcaaccaga cgctggatcg cgaacacgcc atcgagatgc tgcatagctg ctggctgaaa
    11341 ctgctggaag tgaacaagat ccgctccggc tcacactcaa aagcctctgc gggaagtccg
    11401 ctgtatcaga acgttaccat tggcggacaa aatctggttg atggtcaacc aatggatgca
    11461 gtgaatcccc tctcttacgc gatcctcgaa tcctgcggtc gcctgcgttc cactcagcct
    11521 aacctcagcg tgcgttacca tgcaggaatg agtaatgatt tcctcgacgc ctgcgtacag
    11581 gtgatccgtt gcggcttcgg gatgccggcg ttcaacaacg acgaaatcgt gatcccggaa
    11641 tttattaaac tcggtattga accgcaggac gcttacgact acgcagcgat tggttgtatc
    11701 gaaaccgccg tcggtggcaa atggggctat cgctgtaccg gcatgagctt tatcaacttc
    11761 gcccgcgtga tgctggcggc gctggaaggc gggcgtgatg ccaccagcgg caaagtgttc
    11821 ctgccacaag aaaaagcgtt gtcggcaggc aactttaaca atttcgatga agtaatggac
    11881 gcgtgggata cgcaaatccg ttattacacg cgtaaatcaa tcgaaatcga atatgtcgtc
    11941 gacaccatgc tggaagagaa cgtacacgat attctctgct cggcgctggt ggatgactgt
    12001 attgagcgag cgaaaagtat caagcaaggc ggcgcgaaat atgactgggt ttctggcctg
    12061 caggttggca ttgccaacct cggcaacagc ctggcggcag tgaagaaact ggtatttgaa
    12121 cagggcgcga ttggtcagca acagctggct gccgcactgg cggatgactt cgatggcctg
    12181 actcatgagc aactgcgtca gcggctgatt aacggtgcgc cgaagtacgg caacgacgat
    12241 gataccgtcg atacgctgct ggctcgcgct tatcagacct atatcgacga actgaaacag
    12301 taccataacc cgcgctacgg tcgtggtccg gttggcggca actattacgc gggtacctcg
    12361 tctatctccg ctaacgtacc gtttggcgcg caaactatgg caacaccgga cgggcgtaaa
    12421 gcccacaccc cgctggcaga aggcgctagt ccggcctctg gtactgacca tctcggccct
    12481 actgcggtca ttggctcggt gggtaaactg cctacggcag cgattctcgg cggcgtgttg
    12541 ctcaaccaga aactgaatcc ggcaacgctg gagaacgaat ctgacaagca gaaactgatg
    12601 atcctgctgc gcaccttctt tgaagtgcat aaaggctggc atattcagta caacatcgtt
    12661 tcccgcgaaa cgctgctgga ggcgaaaaaa catccggatc agtaccgcga tctggtagtg
    12721 cgtgtcgcgg gctattccgc cttcttcacc gcgctctctc cagacgcaca ggacgatatc
    12781 atcgcccgta ctgaacatat gctgtaatct cctcggcccg gcggcgtcgt cgccgggcta
    12841 aatcattcac atcatcaatt tcatccttac tttcattcga aatataattt gtgctcttcg
    12901 tcacattgtt attacactgt tacggtttca ttttcgagcc aggagcacac ctatgagcgt
    12961 aaaagttatc gtcacagaca tggacggtac ttttcttaac gacgccaaaa cgtacaacca
    13021 accacatttt atggcgcaat atcaggaact gaaaaagcgc ggcattaagt tcgttgtcgc
    13081 cagcggtaat cagtattacc agcttatttc gttctttcct gagctaaagg atgagatctc
    13141 ttttgtcgcg gaaaacggcg cactggttta cgaacatggc aagcaactgt tccacggcga
    13201 actgacccga catgaatcgc ggattgttat tggcgagttg ctaaaagata agcaactcaa
    13261 ttttgtcgcc tgcggtctgc aaagtgcata tgtcagcgaa aatgcccccg aagcatttgt
    13321 cgcactgatg gcaaaacact accatcgcct gaaagctgta aaagattatc aggagattga
    13381 cgacgtactg ttcaagtttt cgctcaacct gccagatgaa caaatcccgt tagtgatcga
    13441 caaactgcac atagcgctcg atggcattat gaaacccgtc accagtggtt ttggctttat
    13501 cgacctgatt attcccggtc tacataaagc aaacggtatt tcgcggttac tgaaacgctg
    13561 ggatctgtca ccgcaaaatg tggtagcgat tggcgacagc ggtaacgatg cggagatgct
    13621 gaaaatggcg cgttattcct ttgcgatggg caatgctgcg gaaaacatta aacaaatcgc
    13681 ccgttacgct accgatgata ataatcatga aggcgcgctg aatgtgattc aggcggtgct
    13741 ggataacaca tcccctttta acagctgacc tctctaccgg agccgtgcgc tccggttttc
    13801 ccttcttttt acatcctgta catcacatca aatcattaaa cttgcattaa cttatttata
    13861 acttatattg tcacatgcaa atcagaatgg tttcgaatga aagttaatga gaggtggtta
    13921 tggcttctac ttttaccagc gacacattgc ctgccgatca caaagcagct atccgtcaga
    13981 tgaagcacgc gctgcgggcg cagcttggcg acgtccagca gatctttaat cagctaagcg
    14041 atgacattgc cacgcgagtg gctgaaatca acgcactcaa agcacagggc gatgccgtct
    14101 ggccggtgct gtcttatgcc gatatcaaag caggtcatgt tactgcagag cagcgcgaac
    14161 agattaaacg tcgcggttgt gcggtgataa aaggccattt cccccgcgaa caagcgctag
    14221 gctgggatca gtcgatgctg gactatctgg accgcaaccg ctttgacgag gtctacaaag
    14281 gccccggcga taatttcttc gggacgctca gcgcttcacg tcccgagatt taccccatct
    14341 actggtcgca ggcgcaaatg caggcccgcc agagtgaaga aatggcgaat gcgcagtcgt
    14401 ttctcaatcg tctgtggaca tttgaaagtg atggaaagca atggtttaac ccggatgtga
    14461 gcgtcatcta ccctgaccgt atccgccgcc gtccgcccgg aacgacctcc aaaggtcttg
    14521 gagcgcatac cgactccggg gcgctggaac gctggctgct tccagcgtat cagcgcgttt
    14581 tcgccaacgt ctttaatggc aatctggcgc aatatgatcc ctggcatgcg gcacatcgta
    14641 cggaagttga agagtacacg gtggacaaca ccaccaaatg ttccgtgttt cggacattcc
    14701 agggctggac agcgctctct gatatgctgc ctggtcaggg gttgctgcac gttgtgccca
    14761 ttcctgaagc catggcgtac gtactgttac gtccgctgct tgatgatgtg ccggaggatg
    14821 aactgtgcgg cgtagcgccc ggaagagtgt tgccggtatc agagcaatgg catccactgt
    14881 taattgaggc gttaaccagc attccaaaac tcgaggccgg agactccgtc tggtggcact
    14941 gcgacgtcat ccattccgtt gcccccgttg aaaatcaaca gggttggggc aacgtgatgt
    15001 acattcctgc ggcaccgatg tgcgagaaaa atcttgccta cgcgcacaag gtgaaggccg
    15061 cactggaaaa aggcgcatcg ccgggcgact tcccgcgcga ggactatgaa acaaactggg
    15121 aaggacgctt tacgcttgcc gacctcaaca ttcacggtaa gcgagcgttg ggcatggatg
    15181 tttgagagtt aatggaagtg aattgatgtg ggattaagaa aatcgattcg acgttactca
    15241 gattgctgac aagtgcgctt tcttaatgcc tgatgcgcta cgcttatctg gcctacaaag
    15301 tcctgcagat tcaatatatt acaggtac
//
LOCUS       DAZUDJ010000093        15093 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.093, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000093 DAZUDJ010000000
VERSION     DAZUDJ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15093
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.093"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            85..1416
                     /locus_tag="ACHY1N_004275"
                     /pseudo
     CDS             85..1416
                     /locus_tag="ACHY1N_004275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308049.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015473 - fimbrial usher porin activity
                     [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
     gene            1429..2387
                     /locus_tag="ACHY1N_004276"
                     /pseudo
     CDS             1429..2387
                     /locus_tag="ACHY1N_004276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial family protein"
     gene            complement(2426..3325)
                     /gene="nhaR"
                     /locus_tag="ACHY1N_004277"
     CDS             complement(2426..3325)
                     /gene="nhaR"
                     /locus_tag="ACHY1N_004277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705976.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HFS4046481.1"
                     /translation="MSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEE
                     RLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADA
                     LSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGL
                     FSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEI
                     LGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERM
                     IQHPAVQRICNTDYSALFSPAAR"
     gene            complement(3391..4557)
                     /gene="nhaA"
                     /locus_tag="ACHY1N_004278"
     CDS             complement(3391..4557)
                     /gene="nhaA"
                     /locus_tag="ACHY1N_004278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006885 - regulation of pH [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HFS4046482.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLET
                     PVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     gene            5143..5295
                     /gene="mokC"
                     /locus_tag="ACHY1N_004279"
     CDS             5143..5295
                     /gene="mokC"
                     /locus_tag="ACHY1N_004279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin MokC"
                     /protein_id="HFS4046483.1"
                     /translation="MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVF
                     TAYESE"
     gene            complement(5399..6529)
                     /gene="dnaJ"
                     /locus_tag="ACHY1N_004280"
     CDS             complement(5399..6529)
                     /gene="dnaJ"
                     /locus_tag="ACHY1N_004280"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFS4046484.1"
                     /translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     gene            complement(6618..8534)
                     /gene="dnaK"
                     /locus_tag="ACHY1N_004281"
     CDS             complement(6618..8534)
                     /gene="dnaK"
                     /locus_tag="ACHY1N_004281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFS4046485.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            8911..9315
                     /gene="yaaI"
                     /locus_tag="ACHY1N_004282"
     CDS             8911..9315
                     /gene="yaaI"
                     /locus_tag="ACHY1N_004282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HFS4046486.1"
                     /translation="MKSVFTISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     gene            9341..10054
                     /gene="msyB"
                     /locus_tag="ACHY1N_004283"
     CDS             9341..10054
                     /gene="msyB"
                     /locus_tag="ACHY1N_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HFS4046487.1"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKNMDEEHKQEFLHAIDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRSAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     gene            10203..10769
                     /gene="satP"
                     /locus_tag="ACHY1N_004284"
     CDS             10203..10769
                     /gene="satP"
                     /locus_tag="ACHY1N_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HFS4046488.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     gene            complement(10804..11391)
                     /gene="mog"
                     /locus_tag="ACHY1N_004285"
     CDS             complement(10804..11391)
                     /gene="mog"
                     /locus_tag="ACHY1N_004285"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HFS4046489.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAAGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE"
     gene            complement(11506..12459)
                     /gene="tal"
                     /locus_tag="ACHY1N_004286"
     CDS             complement(11506..12459)
                     /gene="tal"
                     /locus_tag="ACHY1N_004286"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004801 - transaldolase activity [Evidence
                     IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HFS4046490.1"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL"
     gene            12738..14168
                     /gene="yaaJ"
                     /locus_tag="ACHY1N_004287"
     CDS             12738..14168
                     /gene="yaaJ"
                     /locus_tag="ACHY1N_004287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFS4046491.1"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDVNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     VQANAVARALSFSFDFPPLVTGIILAVFALLAITRGLHGVARLMQGFVPLMAIIWVLT
                     SLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPDIGRQLSPDAWDDVSQE"
     gene            14238..15014
                     /gene="yaaA"
                     /locus_tag="ACHY1N_004288"
     CDS             14238..15014
                     /gene="yaaA"
                     /locus_tag="ACHY1N_004288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HFS4046492.1"
                     /translation="MLILISPAKTLDYQSPLTTMRYTLPELLDNSQQLIHEARKLTPP
                     QISTLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
BASE COUNT         3834 a         3739 c         3561 g         3959 t
ORIGIN      
        1 atattaaacc ttcatcaact tcacatcaag aaattaaaaa ttttaaacat taatctaaat
       61 aataacaacc tgatcacata atcgggtacg attttatccg ataactataa tgctataact
      121 ctgggaaatg gttggaatac accgctgggt gccatctctt tttacgctgc ccgatcgagt
      181 agtaagttaa ataatgatac cagacacgaa ggtacgagct atcaggtcgc ctataataaa
      241 tatctagtac aaacagccac tcgatttagc gtggccgcct ggcgttatgc ttcgcaggat
      301 tacaggacat tcagcgacca tctttacgaa aatgataaac actatcatca gagtgattat
      361 gatgattttt atgatattgg cagaaaaaat agcctttctg ctaatattat gcaaccttta
      421 tccaataatc tgggaaatgt atcattaagt gcgctttggc ggaattactg ggggcgaagt
      481 ggaaatgcta aagattacca attcagttac tccaataact ggcaacacat tagttatact
      541 ttctctgcca gccaatctta tgatgaaaat aataaagaag aggagcgttt taatctgttt
      601 atctccattc ctttctactg gggggatgat attgccaaaa cacgtcacca aattaactta
      661 tcgaattcga cctcattttc caaagatggc tattccccca acaatactgg aattactggc
      721 atagccggtg aacatgatca gttaaattat ggtatatatg ttaatcagca acaacaaaat
      781 aatgatacct cgcttggtac gaatttaagc tggagaactc ccatcgccat aatagatggc
      841 agctatagtc attctaaaaa cgcctggcaa agtggtggaa gtattagtag tggattagtt
      901 gtctggcccg gtggtattaa tatcactaac cagttatccg atacatttgc aattctggat
      961 gcgtctgggt tagaaggtgc acatattaat ggacaaaaat acaatcgaac aaacagcaaa
     1021 ggccaggttg tttacgacct gataatacct catcgtgaaa accatctggt acttgatata
     1081 gcaaacagtg aaagtgaaac agaattgcag ggcaatcgtc aaattattgc accttaccgt
     1141 ggagcagttt cttatgtgca gtttacaact gaccaacgta agccctggta tatacaggca
     1201 ctgcgtcccg atggttcgcc attaaccttt ggctatgacg tactggatct ccaggaaaat
     1261 aatattggag tcgttggcca gggtagtcgc ctttttattc gcgtagatga aattcccact
     1321 ggaataaaag ttgctctcaa tgatgaacag aacttattct gtactattac ttttcaacac
     1381 gttatcgatg aaaacaaaac atatatatgc cagtaaaagg agtttactat gaagtggctt
     1441 ttattaatca ccttgagtct atattctttt attgtgcaaa gtgctccctg tgcattgacc
     1501 aatgtcggtg aacaacgtgg aacatatata ctcaagccac tgagtatgaa aggtaatcta
     1561 accgccgaaa aattgaaaac accggaaata tcattgagtg tacagacttg caagagacaa
     1621 ccaacgccat taaagttcat tttttaacac agaacgcttt aaggtttaaa gtcggaagtc
     1681 gtcattatat tattaatttc ccctttgaat ctgacggtaa aaaaatagag cttccaggga
     1741 agtcatctta taatttagaa gaaatgctat ctgcgataaa tttcaccatt ccatattcta
     1801 tcgcatctgt atcagatagt tctaacaccg cagacatttt tcctggaact ccttttcctt
     1861 tgttgttcga aattgaagtg agttcatgta cagggaataa tactaattgt aatagcgtcc
     1921 gctttaatta taatttaaat actattttac aggtaaattt aatgacctgt ggttttgaag
     1981 atcaatccat cgacactgga cgatttgtac tgtctcgtat caataatgaa aattatcagt
     2041 ttcatcatat aagatttgac tgcatccagg gcgagcaagg tgaattagtt tttgaaccca
     2101 gtgatgttga atattacttt gaaccagtga cgatacagga gtcaggaacc agcatattaa
     2161 aaaatgagtt agaaaacagt gaggacggtg cgggtcaaat aggctttcaa ctctccaatg
     2221 atggtacgaa tgaaatccag tatggtaaaa gcaattacta ctcttttcag catccccatg
     2281 aaggaagtaa tcagattcct ctatttattc gcccgcgtac atatggaaat aatgtctcaa
     2341 gcgggcaaat aatgagccga gtcaaaatcg tggttatgta caactaatct atctccccca
     2401 ccttaacttt ggggggaggt gccgattaac gcgccgctgg actaaaaagc gcagaataat
     2461 ccgtattgca gattcgctgt accgccgggt gctgaatcat ccgctcagca aaaatagcat
     2521 ggtactcttc catcacattc tcgacgcgac caatttctac gacagtttta tcggcataaa
     2581 agtcatatgc ataaagagtt ggggcaacga agattgcatt gtgcatcgca ccaaaagctt
     2641 tcatcaacgc ggcatcatca aactcgccga ggatttctac gtttaatccc tgggagttaa
     2701 accagttaag caatttgcgc cctaacattg aacgtcgccc aggaatcaaa agtcgccgtt
     2761 cttccagaca agccgggaac ggtttttctg gtggtggatt tgtacaccag aaactcacgc
     2821 cacattcgcc aattctcacg gagaacaggc cttcctgctg cgtagagtct atcggacagt
     2881 cagaaatgat catatccagt ttatgctgac ttaattgctc cagcagcatt tcgtgggtgg
     2941 attcgaagca gcgaagatga atgggctcgc cttctaccac tgcggcgtta agtacgctac
     3001 tgaccaggcg tttggaaagt gcatcagcca caccaacgtc aaacaataaa ttggattctt
     3061 tgcgatagtt cacaatatcc agcatttcct ggcttaaggt gaacatttta tcggcatagc
     3121 gatagaccag ttctcccagc tcgctgggtt cgagaccacg tcccttgcgt ttaaataatt
     3181 tgccttgcag gcgctcttcc agcgctcgaa tctgtccggt aatggtttgt ggagttaaat
     3241 aaagcgcctc cgctgcgcca accacggaac cttctttata gacatgccag aagtaataca
     3301 agtggttgta attgatatga gacatgctca tttctctccc tgataacaat gaaaagggag
     3361 ccgtttatgg ctccccggta aaccgtcctg tcaaactgat ggacgcaaac gaacgcgtaa
     3421 ccagctgtat ccaattaccg ccgaagagat agaaccgacc aggataccga gtttcgccca
     3481 gttaatcagt tctggatcta cgctaccaaa ggccaggctg gcaataaaga tagacatagt
     3541 aaaaccgata ccgcacagga tccccaccgc cataatttgc tgataagtcg ttccctcagg
     3601 cagatgcgcc agtttcaaac gcagcgccaa ccagcagaac agactaatcc ccagcggttt
     3661 gccaatcagc aagccagcga tgatccccaa tggcagaatg gaggtcaagc catccagcgt
     3721 gacaccttgc agtgaaacgc cagcattagc aaatgcaaac agcggcaaaa tcagatacgc
     3781 cacccacggg tgtaacacat gctccagtcg cttcgctgga gaacgcccat gcttctcttt
     3841 caaaggaata aagaagccga caattacccc cgccagggtt gcgtgaaccc ccgatttcaa
     3901 caccgcagtc cacaacacta cgccaaccag aatatagacg cccgtgcggc gtacaccaca
     3961 cagattcaat accgcgagta ccgcaattgc tacagccgcg acaccaagag aggccatcga
     4021 taagtcatta gtgtagaaca atgcgatgat aatgatggcc ccaagatcgt cgataatagc
     4081 cagagccatc aaaaagatct tcagcgctaa cggaacacga cttcccaaca gcgccagcac
     4141 accaagtgca aaggcaatgt cagtagccgc cgggatcgcc cacccttcgc gggtaatcgg
     4201 atcggcatag ttaaaggcca gatagagtaa tgccggaaca atcatcccac caatagcggc
     4261 gataactgga aatgcggcct ggcgtaagct ggctagcgat ccttgcatca gttcacgttt
     4321 aacttccaga ccgactaaca ggaaaaatac cgccatcagc gcgtcattta tccataacag
     4381 catgtttttg ttgatttcga gtgaaccaac ccggagctga accggcgtct ccagaaagtc
     4441 gtgataccat ccactggttg cgccgctatt ggccataatc atcgccagga tagcggcaat
     4501 gataagaata atgcctcccg aggcatcact gctaaagaat cgatgcagat gtttcacttt
     4561 ttatttctct ttcaggtgaa tagatcgttt ttactatttt accccgcaca aatcatcgtt
     4621 aaaatcagat tatagtgtag gaataactcg ttttttacga tccattgaag aatttgcgcc
     4681 atcagcggtg agatgagttt ttgacggctg taagcgctca cgagtgaccc taagcccaga
     4741 taatcatagc ttaaggtgag gatttctgag agattaatta ggaaaagtaa taattaattt
     4801 gttgtcagtc ggcgatgttt gttaggccaa tatttcaaaa ataatccagc ttgtcgtcaa
     4861 taattgcgat gaagagataa attaaagtta aataattaaa tcattaaaaa attacgccat
     4921 aaaaatgcga ggcgtcttca ggattagaat cgataaaaca gaatgggtta aagagagcga
     4981 tataatagcg gcgggtgctt gaggctgtct gtctcaggca ttagctgaac ggcagataga
     5041 gaaaagcccc gagtgatatt ttaccatcaa cccgaggccc cctatatgct gaacacatgt
     5101 agagtgcctc ttactgaccg taaggtcaag gagaagagag caatgaagca gcataaggcg
     5161 atgattgtcg ccctgatcgt catctgtatc accgccgtag tggcggcgct ggtaacgaga
     5221 aaagacctct gtgaggttca catccgaact ggccagacgg aggttgctgt tttcacggct
     5281 tacgaatccg agtaagagca acggcgggga gtgatccccg ccactttaca ggtgctcgca
     5341 tatcttcaac gcaccctatt tttacccagg cctgcccacg ggcaggcttt tggggaggtt
     5401 agcgggtcag gtcgtcaaaa aacttcttca caccatcaaa gaagctcttt gagcgcgggc
     5461 tgttgtgctc accggttggg ccaccgaagc tttcttgcag ctcttgcagc agctgtttct
     5521 gcttctcgtt caggcctacc ggtgtttcga cgacaacgcg gcacagcaaa tcaccctgtg
     5581 cgccaccgcg gacagacttg acgcctttac cgcgcatacg gaaaagctta ccggtctggg
     5641 tttcgccagg cactttcagt ttgacgcgac catcaagggt cggtacttcg atttcgccac
     5701 ccagcgccgc catagcgaag ttgatcggga cttcgcaata gaggttgttg ccttcacgct
     5761 cgaaaatcgg gtgctgttta acctgaacct gaacgtacag atcgcctgcc ggtgcgccat
     5821 gctcgcccgc ttcaccttcg cccgcaagac ggatgcggtc tccagtgtcc acccctgccg
     5881 ggattttaac ggacagcgtt ttgctgcgct caacacgacc atgaccatga catttgttgc
     5941 acggatcttt gatcagcgta ccgcggccct gacagtgtgg acaggtctgc tgtacagcga
     6001 agaatccctg acgcatctgc acctgaccag aaccatgaca ggtcggacag gtctgcggct
     6061 gtgtacctgg ttttgcaccg ctaccgtggc aaacgtcaca ctcttccaga gtcggaatgc
     6121 ggatctcttt ggtcacgcca cgtacagctt cttcgagggt gagctccatg ttatagcgta
     6181 aatcagcacc gcgcgccgca cgttgacgac cacgtccgcc gccaaaaata tcgccgaaaa
     6241 cgtcaccaaa aatatcgctg aagtctgcgc cgccgccaaa accgccgccg cccataccac
     6301 cttgctcaaa cgcagcatga ccatactgat cgtatgccgc acgtttttgc gagtcggtca
     6361 gaacttcata agcttccttg atctctttaa atttcgcctc ggcctctttg tcaccctggt
     6421 tacggtccgg gtggtatttc atggccaggc gtttgtaggc ctttttgatt tcacgctctt
     6481 ccgctgtttt ggaaacgcct aaaatctcgt aataatcttg cttagccatc ttttttaaat
     6541 tgcccctaga tgaatgcacg ggcggagagg aaattcccct tcgcccgtgt cagtataatt
     6601 acccgtttat agggcgatta ttttttgtct ttgacttctt caaattcagc gtcgacaaca
     6661 tcgtcatctt tcgcgttgtt tgcagaagca tcagcaccgg cagtctgctg ctgggcatgt
     6721 tgctgctggg cgatttccat cagtttctgg gaaacctgtg ccagctcctg cattttcgct
     6781 tcgatagcgg ctttgtcttc acctttcaga gcagtttcca gtgcagtcag tgcagactcg
     6841 atagcagttt tgtcgtcagc cggcagtttg tcgcctgctt cttcaacctg cttacgggtg
     6901 ctgtgcagca gatggtcgcc ctggttgcga gtctgtacca gctcttcaaa cttacggtca
     6961 gcttcggcgt tagcttctgc gtcgcgtacc attttctgga tttcatcttc gttcagacca
     7021 gaagaagcct tgatggtgat cttctgctct ttaccgctgt ttttatcttt cgcggaaacg
     7081 tgcaggatac cgtcagcatc gatatcgaag gtaacttcga tctgcggcat gccgcgcggt
     7141 gccgggttga taccatccag gttgaactga cccagagatt tgttatcagc cgcacgttta
     7201 cgttcaccct gcagcacatg gatggttacc gcagactggt tgtcttcagc ggtagagaac
     7261 acctggctgt gcttggtcgg gatagtggtg tttttcgcga tcagcgtcgt catcacaccg
     7321 cccatggttt cgatacccag agacagcggg gtaacgtcca gcagcagtac gtctttcacg
     7381 tcaccagtca gaacaccacc ctgaacagca gcaccgattg ctacagcttc gtccgggtta
     7441 acgtctttac gcggctcttt accaaagaac tcagcaactt tcttctgaac cattggcata
     7501 cgagtctgac caccaacgag gataacgtcg tcgatatcag atacggacag gccagcgtcc
     7561 tgcagtgcaa ctttcagcgg ctcaatggaa cggtttacca gatcttcaac caggctttcc
     7621 agtttcgcac gagtcacttt gatgttcatg tgtttcggac cggtcgcatc tgcagtgatg
     7681 tacggcaggt taacgtcggt ctgctgagcg gaagacagtt cgattttcgc tttttctgcc
     7741 gcttctttca ggcgctgcat tgccagcgga tcgttgcgca ggtcaatgcc ctgatctttc
     7801 ttgaattctt caaccaggta gttgatcaga cggctgtcga agtcttcacc acccaggtgg
     7861 gtatcaccgt tggtagccag aacttcgaag gttttttcgc cgtcaacttc gtcgatttcg
     7921 ataatagaaa tatcgaaagt accaccaccc aggtcataaa ccgcgatagt acggttgcca
     7981 gtacctttgt ccagaccgta agccagcgca gctgcggtcg gttcgttgat gatacgtttt
     8041 acttccagac cagcgatacg gcctgcgtct ttggttgcct gacgctgagc atcgttaaag
     8101 tatgccggta cggtgataac agcttcagtt accggttcac ccaagtaatc ttcagcggtt
     8161 ttcttcattt ttttcagcac ttcagcagag atctgcggcg gtgccatttt ctggccttta
     8221 acttcgaccc atgcgtcgcc gttatcagca gcaataattt tgaacggcat gatggaaaca
     8281 tcacgctgta cttcttcgtc ctggaagcgg cggccaatca ggcgtttaat cgcaaacagg
     8341 gtgttttgcg ggttcgtcac tgcctgacgt ttagccggct gaccaaccag agtttcacca
     8401 tcctgggtat aggcaatgat agaaggcgtg gtgcgatcgc cttcggcgtt ctccagcacg
     8461 cgaggagtgg tgccatccat aatcgctaca caagagttgg tagtacccag gtcgatacca
     8521 attattttac ccatctaaac gtctccacta tatattcggt catcatgtgg ttgtgagtct
     8581 gtaatagggg cgaaacgtct ggtttcaact gcccaatttc atttttttgc agactcactc
     8641 actgcggttg actactaaat ggggtcgtaa cccacgtcat caagggggag atgcaaaaat
     8701 tttttgtgct tttgcgcaga aatttcgcga tatagcagga caagacgtga aactgacagc
     8761 aattttattc atataaagaa tgaatcgcag ccaagacatt catcaaaaaa ttgtaataaa
     8821 aagaaaacat tacgcacctg aatcttctct ttatcagcag taaactagtg ggtatccatc
     8881 cccctacctc tccccactaa gagaatcctt atgaaatccg tttttacgat ttccgccagc
     8941 ctggcgatta gtctgatgct gtgctgcacg gcgcaggcaa acgaccataa aatcctcggc
     9001 gtcattgcaa tgccgcgtaa cgaaaccaac gatctggcgt tgaaacttcc tgtttgccga
     9061 attgttaaac gcatacaact ctctgccgac catggcgatt tacagttaag cggtgcatcg
     9121 gtttatttca aagccgcccg tagcgccagt cagagcctga atattccttc agaaataaaa
     9181 gaagggcaaa ccactgactg gatcaacatt aacagcgata acgacaataa acgctgcgtc
     9241 tcaaaaatca ccttttccgg tcatacggtg aactcatcgg atatggccac gctgaaaatt
     9301 atcggcgacg actaacgcca gaatatagaa gccacaaaaa atgaatgtta attacctgaa
     9361 tgattcagat ctggattttc tccagcattg cagtgaggaa cagttggcaa atttcgcccg
     9421 attgctcacc cataatgaaa aaggcaaaac tcgcctctcc agcgtactga tgcgcaacga
     9481 actgtttaaa tcgatggaag ggcatcccga gcaacatcgc cgcaactggc agctgattgc
     9541 tggagaatta cagcattttg gtggcgatag tatcgccaac aaactgcgcg gacacggtaa
     9601 attgtatcgg gccattttgc tcgatgtttc aaaacgattg aagctgaaag ccgacaaaga
     9661 gatgtctacg tttgagattg agcaacagtt actggaacaa tttctgcgta acacctggaa
     9721 gaatatggac gaggaacata agcaggagtt tctgcacgcg atcgatgcca gggtgaatga
     9781 gctggaagag ctgctgccgc tgctgatgaa agacaaatta ttggcaaaag gcgtgtcgca
     9841 tttgctttcc agccaactga cccgcatttt acgcacccac gcagcaatga gcgtacttgg
     9901 gcatggtttg ctgcgcagcg cggggctggg aggccctgta ggtgcggcac taaatggggt
     9961 taaagcggtc agcggcagcg cctatcgcgt gacgattcca gccgtactgc aaatcgcctg
    10021 cctgcgccgg atggttagcg ccactcaggt ctgataccgg aaaccgggga aaattttcat
    10081 tttcccctca aaagatcgta gacactgccc cactggctga ttattatgcc gcgccctgaa
    10141 aacactacag ttattcaggg aaattatttc accattcatt cgatgatgat ttttgaggaa
    10201 ttatgggcaa cactaagttg gctaatccgg caccgctggg cctgatgggc ttcggcatga
    10261 ccaccattct gcttaacctg cacaacgtgg gttatttcgc tctggacggt attattcttg
    10321 ccatgggcat tttctacggc ggcatcgcgc aaatttttgc tggtctgctg gagtacaaaa
    10381 aaggcaacac tttcggttta accgcattca cctcttacgg ttctttctgg ctgacgctgg
    10441 ttgcgattct gctgatgccg aaactgggtc tgaccgatgc gccaaatgca cagttccttg
    10501 gtgtctacct gggtctgtgg ggcgtattta cgctgtttat gttcttcggc acgctgaaag
    10561 gcgcacgcgt tctgcaattc gttttcttta gcctgaccgt gctgtttgcc ctgctggcga
    10621 tcggtaacat tgccggtaac gccgcaatca tccactttgc cggctggatt gggctgatct
    10681 gcggtgccag cgcaatctat ctggcgatgg gtgaagtact gaacgagcag tttggtcgca
    10741 ccgttctgcc gattggtgaa tcccactaat tgttttgaga tccccccgct cggggggatt
    10801 tttttattcg ctaacgtcgc gtcttgcact cttcggtctg aatgctgcaa ccacttccgg
    10861 tgccgtttca acgtatggcc cttccagcaa ctgaatgcag tacggtacgc tggcaaaaat
    10921 accgtgtacc acaacgttac ccgcagcgtc cttcacacct tccagcgtct ctttaataga
    10981 cttcggctga ccgggtaagt taaggatcag cgcctgtttg cgaatcacgc ccacctgacg
    11041 cgaaaggatc gcagttggta caaaatgcag gctgatctgg cgcatctgtt caccaaagcc
    11101 aggcatctcg cggtccgcta ctgccagcgt cgcatcgggc gttacgtcac gacgcgccgg
    11161 gccagttccg cccgtggtga gcaccagatg gcaactcatt tcatccacta gctcacacaa
    11221 cgtttgctcg atgatcgcct gctcatcggg gattaagcgg gtttccagtt caaacggcgt
    11281 ggttagcgcc gatgtcagcc attcttccag cgcagggatg cctttatcct gataaacgcc
    11341 gctggatgcg cgatcagaga tggaaactaa gccaatacgt aaagtattca tcaagatttt
    11401 tccgtttaaa cagtctcgtt aaacagaatg atacactgcg aagggagtga cagacaggct
    11461 tcagaagagg tagcgtgacc gacttcccgg tcacgctaag aatgattaca gcagatcgcc
    11521 gatcattttt tccagttttt cctggtcaat agcaaactta cggatacctt ccgccagttt
    11581 atctactgcc attggatcct ggttgtgctg ccacaggaac tcggactcag tgatacgcgc
    11641 cggacgcgct ttcacttcgc cggtgtaaga cagtttacgt tcgatagccc cttcgctctc
    11701 cgccagctct ttcagcagtg ccggtgcgat ggtcagacgg tcgcagcctg ccagttccag
    11761 aatttcgccg atgttacgga agcttgcgcc cataaccact gtttcataac cgtgctcttt
    11821 gtagtactgg tagatttcag atacagaaac cacgcccgga tcttctgccg gagcgtactc
    11881 tttcttatca gtattcgctt tgtaccagtc aagaatacgg ccaacaaatg gcgagatcag
    11941 gaacacgcct gcttccgcac aagcacgagc ctgagcgaag gagaacagca gggtcaggtt
    12001 acagttgatg ccttcttttt ccagctgttc tgcagcacgg ataccctgcc aggtagaagc
    12061 cagtttgatc agaatacgat cgttgctaat accagcatcg ttgtagagtt tgatcaggcg
    12121 ttttgctttc gcaattgacg cttcggtgtc ataggaaaga cgcgcatcaa cttcagttga
    12181 gatacggccc ggaaccagtt tcaggatttc cagaccaata tttactgcca gtttgtcggt
    12241 cgcgtccacg atctgctgcg cgcgatcgtt gctctgctgt ttcgcccaag cgacagcatc
    12301 atcaatcaac ttacggtatt ccggaatctg cgctgcgtta agaatgagag aagggttggt
    12361 tgtggcatcc tgcggttgat acagcttcat tgccgcgatg tccccagtgt cggccactac
    12421 ggtggtgtac tgacgaaggg aggtcaattt gtccgtcatg atagtatttc tctttaaaca
    12481 gcttgttagg gggatgtaac cggtctgccc tgatgatatc acgacgcaac gtcagcgcaa
    12541 ccgccgacaa gacggttatc gccaggcgag actgtttcgg atttctgaca ctgcgttgat
    12601 atcgcccgcc atttttatac aaaacctcat gtatgctacg cagaagttat caagtacctc
    12661 gtagcgtata tacttcttaa acaattggta acgtttacac aggaaagtca tcgcgaccgg
    12721 caataagagg gatatgcatg ccagattttt tctcctttat taacagcgtc ctttggggat
    12781 cggtaatgat ttacctgctc ttcggcgcag gttgttggtt cacttttcgc accggatttg
    12841 tgcagtttcg ctacatccgc cagtttggca aaagtcttaa aaatagcatt catccacagc
    12901 caggcggttt aacctcattt cagtcattgt gtaccagtct tgcggcgcgc gtgggtagcg
    12961 gcaacctggc cggcgttgcg ctggctatta ccgccggtgg acctggagcc gtcttttgga
    13021 tgtgggttgc cgcgtttatc ggcatggcga cctcgtttgc cgaatgttcc cttgcacaac
    13081 tttataaaga acgtgacgtc aatggacagt ttcgtggagg accggcatgg tatatggcgc
    13141 gcgggctggg gatgcgttgg atgggcgttc tgttcgccgt ctttttgctc atcgcctacg
    13201 gcataatttt cagcggagtt caggcgaacg ccgttgcccg agccctgagt ttttcttttg
    13261 attttccccc gctggtgaca ggcattattc tcgctgtctt tgctctgctg gcaatcactc
    13321 gcggtcttca tggcgtcgcc cggctcatgc agggttttgt cccgttgatg gcgataatct
    13381 gggtactgac cagcctggtg atttgcgtaa tgaatatcgg gcaacttccc cacgtcattt
    13441 ggtctatttt tgagagtgct tttggctggc aggaagcggc aggcggcgcg gcgggatata
    13501 ccttaagcca ggcgattact aacggttttc agcgcagtat gttttccaat gaggcgggaa
    13561 tgggttctac accaaacgca gcagcggcag ctgcgtcctg gcctccgcat ccggcagcgc
    13621 aagggattgt ccagatgatt ggcattttta tcgacaccct ggtcatctgt acggcaagcg
    13681 ccatgctgat attactggcg ggtaacggca caacctacat gccgctggaa ggtattcagc
    13741 ttatccagaa ggcgatgcgg gtgctaatgg gttcctgggg tgctgagttt gttaccctcg
    13801 tggttattct gtttgccttc agctccatcg ttgccaacta catttatgcc gaaaacaatc
    13861 tcttcttttt acgcctgaac aaccctaaag cgatctggtg tttgcggatc tgcaccttcg
    13921 caacggtcat cggcggcacc ttgctaagtc ttccgctgat gtggcaactg gcagatatca
    13981 taatggcctg catggctatt accaatttga ccgccatttt actgctctcg cctgtggttc
    14041 ataccattgc cagtgattat ctacgccagc gtaaactcgg cgtgcgcccg gtgtttgatc
    14101 cgttgcgtta tccggatatc ggtcgccagc tttctccgga cgcgtgggat gatgtttcgc
    14161 aggagtaatc acaactatcg atcaactcat tctctttttt tgctaaagtc ggcataaatt
    14221 tcctgcaagg actggatatg ctgattctta tttcacctgc gaaaacgctt gattaccaaa
    14281 gcccgttgac caccatgcgc tatacgctgc cggagctgtt agacaattcc cagcagttga
    14341 tccatgaagc gcggaaactg acgcctccgc agattagcac gctgatgcgc atcagcgaca
    14401 aactggcggg tatcaacgcc gctcgctttc atgactggca gccagatttc acgccggaga
    14461 atgcccgcca ggcgattctg gcgtttaaag gtgatgtcta caccggcttg caggccgaaa
    14521 ccttcagcga agacgatttc gattttgccc aacagcattt gcgaatgctt tccggcttgt
    14581 atggcgtact gcgcccgctc gatttaatgc agccttatcg tctggaaatg gggatccgtc
    14641 ttgagaatgc ccgagggaaa gatctgtatc aattctgggg agatatcatc accaacaagc
    14701 tgaacgaggc gctcgcagca caaggcgata atgtggtgat taatctggcg tcagatgagt
    14761 attttaaatc ggtgaagccg aagaaattga atgccgagat tatcaagccg gtgttcctcg
    14821 atgagaagaa cggcaaattt aagatcatca gcttctacgc taagaaagca cgcggtctga
    14881 tgagtcgttt cattattgaa aatcggctga ccaaaccaga gcaactgact ggttttaata
    14941 gcgaaggtta cttctttgat gaagcttcct ccagcaatgg tgaactggtg tttaaacgct
    15001 acgagcagcg ttaagtttgt agccaatgcc ggatgcggcg tgaacgcctt atccggccta
    15061 caaaagcatg cagattcaat atattgcaga att
//
LOCUS       DAZUDJ010000094        14842 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.094, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000094 DAZUDJ010000000
VERSION     DAZUDJ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14842
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.094"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(87..794)
                     /gene="yqgA"
                     /locus_tag="ACHY1N_004289"
     CDS             complement(87..794)
                     /gene="yqgA"
                     /locus_tag="ACHY1N_004289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFS4046493.1"
                     /translation="MVIGPFINASAVLLGGVLGALLSQRLPERIRISMTSIFGLASLG
                     IGILLVVKCANLPAMVLATLLGALIGEICLLEKGVNTAVAKAQNLFRHSRKKPTHESF
                     IQNYVAIIVLFCASGTGIFGAMNEGMTGDPSILIAKSFLDFFTAMIFACSLGIAVSVI
                     SIPLLIIQLTLAWAAALILPLTTPSMMADFSAVGGLLLLATGLRICGIKMFPVVNMLP
                     ALLLAMPLSAAWTAWFA"
     gene            947..1030
                     /gene="yqgH"
                     /locus_tag="ACHY1N_004290"
     CDS             947..1030
                     /gene="yqgH"
                     /locus_tag="ACHY1N_004290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YqgH"
                     /protein_id="HFS4046494.1"
                     /translation="MHATSLHSLAYRRFARNVSLSMLLLMR"
     gene            1192..3327
                     /gene="speC"
                     /locus_tag="ACHY1N_004291"
     CDS             1192..3327
                     /gene="speC"
                     /locus_tag="ACHY1N_004291"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
                     /protein_id="HFS4046495.1"
                     /translation="MKSMNIAASSELVSRLSSHRRVVALGDTDFTDVAAVVITAADSR
                     SGILALLKRTGFHLPVFLYSEHAVELPAGVTAVINGNEQQWLELESAACQYEENLLPP
                     FYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGD
                     LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKS
                     NHHGALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKAELPRPFR
                     LAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLELNE
                     NDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP
                     LFAALDVNAKIHEGESGRRLWAECVELGIESRKAILARCQLFRPFIPPVVDGKLWQDY
                     PTSVLASDRRFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGINAETGEYSDFGVP
                     ATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLAE
                     VLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAH
                     SAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNL
                     LPGFSPELQGVYSETDADGMKRLYGYVLK"
     gene            complement(3376..4632)
                     /gene="nupG"
                     /locus_tag="ACHY1N_004292"
     CDS             complement(3376..4632)
                     /gene="nupG"
                     /locus_tag="ACHY1N_004292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupG"
                     /protein_id="HFS4046496.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAQVTTPEAMFLVILIN
                     SFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
                     QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSM
                     LLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLS
                     RYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVE
                     KEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSV
                     VLAFAFMAMFKYKHVRVPTGTQTVSH"
     gene            complement(4834..5913)
                     /gene="mltC"
                     /locus_tag="ACHY1N_004293"
     CDS             complement(4834..5913)
                     /gene="mltC"
                     /locus_tag="ACHY1N_004293"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417438.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008933 - lytic transglycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HFS4046497.1"
                     /translation="MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQF
                     AHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRA
                     IIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLK
                     NRLQSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTES
                     SFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAM
                     LNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLT
                     TRHPSAESRRYLYKVNTAQKSYRRR"
     gene            complement(5978..6253)
                     /gene="yggX"
                     /locus_tag="ACHY1N_004294"
     CDS             complement(5978..6253)
                     /gene="yggX"
                     /locus_tag="ACHY1N_004294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HFS4046498.1"
                     /translation="MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK"
     gene            complement(6281..7333)
                     /gene="mutY"
                     /locus_tag="ACHY1N_004295"
     CDS             complement(6281..7333)
                     /gene="mutY"
                     /locus_tag="ACHY1N_004295"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFS4046499.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEMMLQQTQ
                     VATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGG
                     KFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEV
                     ENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWAL
                     YPGKKPKQTLPERTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRHWLAQ
                     RQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSSFTGCMDEGNALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            7494..8213
                     /gene="trmB"
                     /locus_tag="ACHY1N_004296"
     CDS             7494..8213
                     /gene="trmB"
                     /locus_tag="ACHY1N_004296"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFS4046500.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGA
                     CLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            8213..8539
                     /gene="yggL"
                     /locus_tag="ACHY1N_004297"
     CDS             8213..8539
                     /gene="yggL"
                     /locus_tag="ACHY1N_004297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417434.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggL family protein"
                     /protein_id="HFS4046501.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEERKLDEVRTSEL
                     FDVWWD"
     gene            8723..9442
                     /gene="yggN"
                     /locus_tag="ACHY1N_004298"
     CDS             8723..9442
                     /gene="yggN"
                     /locus_tag="ACHY1N_004298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HFS4046502.1"
                     /translation="MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAELRSTLPWIDEGAKSRVEKARIAL
                     DKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQQLV
                     NQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGNLK"
     gene            9618..10664
                     /gene="ansB"
                     /locus_tag="ACHY1N_004299"
     CDS             9618..10664
                     /gene="ansB"
                     /locus_tag="ACHY1N_004299"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004067 - asparaginase activity [Evidence
                     IEA];
                     GO_process: GO:0006528 - asparagine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HFS4046503.1"
                     /translation="MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATK
                     SNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKT
                     DGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KASANRGVLVVMNDTVLDGRDVTKTNTTDLATFKSVNYGPLGYIHNGKIDYQRTPARK
                     HTSDTPFDVSKLNELPKVGIVYNYANASDLPAQALVDAGYDGIVSAGVGNGNLYKSVF
                     DTLATAAKNGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQ
                     TKDPQQIQQIFNQY"
     gene            10781..11788
                     /gene="yggM"
                     /locus_tag="ACHY1N_004300"
     CDS             10781..11788
                     /gene="yggM"
                     /locus_tag="ACHY1N_004300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 family protein"
                     /protein_id="HFS4046504.1"
                     /translation="MKKQWIVGTALLMLMTGNAWADGEPPTENILKDQFKKQYHGILK
                     LDAITLKNLDAKGNQATWSAEGDVSSSDDLYTWVGQLADYELLEQTWTKDKPVKFSAM
                     LTSKGTPASGWSVNFYSFQAAASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLESALN
                     TQKNSIPALEKEVKALDKQMVAAQKAADAYWGKDANGKQMTREEAFKKIHQQRDEFNK
                     QNDSEAFAVKYDKEVYQPAIAACHKQSEECYEVPIQQKRDFDINEQRRQTFLQSQKLS
                     RKLQDDWVTLEKGQYPLTMKVSEINSKKVAILMKIDDINQANERWKKDTEQLRRNGVI
                     K"
     gene            complement(11844..13145)
                     /locus_tag="ACHY1N_004301"
     CDS             complement(11844..13145)
                     /locus_tag="ACHY1N_004301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708726.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFS4046505.1"
                     /translation="MDSYIAITLFGCFFVLVFIGVPISFSIGIATVASMLLMFPWDIA
                     AITVSQRLANGLDNFALLAIPFFIFAGTLMNSGGIAIRLINLAQVMVGRVPGSLGHVN
                     VLANMMFGSISGSAVAAAAAVGGTLNPIQTKQGYDPAFSTAVNVSSCITGLLIPPSNV
                     LIVFSLTAGGVSVASLFMAGYLPGILMGLAVMIVCGIIAKRRGYPLSERATFAQACKA
                     FLDALPSLLLVFIVMGGILGGIFTATEASAIAVVYTFILSVLIYREVKWRHLPKLILE
                     SVVTTSIVLLLIGFSVGMSWAMTNADIPYMISDALMGISDNPLIILLLINIVLLIVGI
                     FMDMTPAVLIFTPIFLPIAQELGMDPVHFGIMMVANLCIGLLTPPVGSALFVGCSISG
                     VKIQHLIKPLLPFYAALLVALMMITYIPQISLFIPQLLGLM"
     gene            complement(13145..13648)
                     /locus_tag="ACHY1N_004302"
     CDS             complement(13145..13648)
                     /locus_tag="ACHY1N_004302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708723.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFS4046506.1"
                     /translation="MIFNRLKLAVDRVIAAFSVAVMLALVVCVVWQVFSRYVLNQPST
                     LTDELARFLMIWVGLLGAAYTVGAQRHLSIDLFALALNKRKQLLLSIVINVLILGFAG
                     SVIVTGGLKLIDKTLATSQVSAAMQIPMGYVYIILPLSGLVMMFYALCFINQSIQQLK
                     QHAQEAS"
     gene            complement(13693..14679)
                     /locus_tag="ACHY1N_004303"
     CDS             complement(13693..14679)
                     /locus_tag="ACHY1N_004303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFS4046507.1"
                     /translation="MKMRSFTRSLVCASLLTLVSTGVNAAEKVTLKLAHNLERSHVVH
                     QSFEELAKEVKQLSKGNMVIRIYPSSQMGNARETMELLQNGALDMTKGSASDLESFDN
                     IYAIYNLPFLFKDQAHFNKVVFGEVGKEIMDSTKDKGFFALSAYVAGTRSFYAKKPIT
                     KPEDLKGLKIRVQPSPTTIKMIELMGGSPTPISFGEVYTAMQQGVVDGAENNVPSWVQ
                     TRHIEIAKVFSEDEHASIPDFLVISTKTWNKLTPEQQQILETATKKSEAYQQKLWEKI
                     DADTRAQAKAMGGEIVKVDKAPFRAAVQPLFDDFKKDPKQAALLEKFDNAAQ"
BASE COUNT         3945 a         3537 c         3744 g         3616 t
ORIGIN      
        1 gattcgcctc gtctcgtcaa tcaaatttct tcaatttact gcagactgca caatctatca
       61 tcactttgcc gctattgcac gcattgtcag gcaaaccagg cggtccaggc ggcggaaagc
      121 ggcattgcca gaaggagtgc tggaagcatg ttgaccaccg ggaacatttt aatgccacag
      181 atgcgtaatc cggttgccag cagcaataaa ccgcctacgg cgctgaagtc tgccatcatc
      241 gacggtgtgg tcagcggtaa tatcagcgcg gcagcccacg ccagcgttaa ctggatgatc
      301 agtaatggga tactaattac cgacaccgca atacccagcg agcaggcgaa gatcatcgcc
      361 gtaaagaaat caagaaatga cttggcgatt aaaatactcg gatcgccggt catcccttcg
      421 ttcatcgccc cgaagatccc ggtgccgctg gcgcaaaaca ggacaataat cgcgacataa
      481 ttctgaataa aagattcatg cgttggcttc ttacgtgagt gacgaaacag attttgtgct
      541 ttggcgactg ctgtattgac acctttctcc agcaaacaaa tttcgccaat tagagcgcca
      601 agtagcgtag ctaaaaccat cgctggaagg ttggcgcatt tcacaaccag taaaatacca
      661 atccccagcg atgccagacc aaaaatagat gtcatggaga tgcggatacg ttccggtaag
      721 cgttggctga gcagtgcgcc gagaacgcca cccagtaaga ctgcactagc gttgataaaa
      781 gggccgatga ccacaagagt tcctgttaac tgtattgttt gattttctta ttatgaactt
      841 tttgccttgt tgatggcttg tctggtcgca aagtcctggc ttgcacgctt tagcgaaagg
      901 tgccatgatt gcgcgaattt tctcctctct gtacggagtt tgcccgatgc acgccacctc
      961 cttacattct ctcgcttatc gccgtttcgc gcgaaacgtt tccctttcta tgttactgct
     1021 catgcggtga agttaacgca cgctcactgc aggacaacag taaaatcaga gcgtttctgc
     1081 ttttactgat gtctggcggt cggagctggt gaccagtttg acccatatct catggggcag
     1141 ggttttccac cttgtccggt attcttactt ccccgaaacg ggtttgcgct tatgaaatca
     1201 atgaatattg ccgccagtag tgaactggta tcccgacttt cttctcatcg tcgcgtggtg
     1261 gcgttgggag atactgattt tacggacgtc gcggcagtcg tcattaccgc tgcggatagt
     1321 cgcagtggca ttcttgcgtt gcttaagcgc accggttttc atctaccggt gtttttgtat
     1381 tccgaacatg ctgttgaatt acctgcgggc gttacggcgg taatcaacgg caacgagcag
     1441 cagtggctgg agctggaatc cgcagcctgt cagtatgaag agaatttgct gccaccgttt
     1501 tatgacacgc tgacgcagta cgttgagatg ggcaacagca cctttgcttg ccctggacat
     1561 caacatggtg cgttttttaa aaagcatcct gccggacgcc atttttacga tttctttggt
     1621 gagaacgtct ttcgcgccga tatgtgtaac gctgacgtaa aattgggcga tctgcttatt
     1681 catgaaggat cggcgaaaga tgcgcagaaa ttcgcagcca aagtctttca tgccgataaa
     1741 acctattttg tgctgaacgg cacatcggca gcgaataaag tggtgacgaa tgcgctgtta
     1801 acgcgtggcg atctggtgct cttcgaccgt aacaaccata agtcgaatca tcacggcgcg
     1861 ctgattcagg cgggggcgac gccggtctat ctggaagctt cacgcaaccc gtttggtttc
     1921 attggcggta ttgatgcgca ctgttttaat gaagagtatc tgcgccagca aattcgcgac
     1981 gttgcgccag aaaaagccga gctgccgcgc ccgtttcgcc tggcgattat tcagctggga
     2041 acctatgacg gaactgtcta taacgcccgt caggtgatcg ataccgttgg gcatctgtgt
     2101 gattacattc tgtttgattc cgcgtgggtc ggttacgaac agtttatccc gatgatggcg
     2161 gatagctcgc cgctgctatt agaacttaac gaaaacgatc cggggatttt tgtgacccag
     2221 tcggtgcaca aacagcaggc tggattctca cagacgtcgc agatccataa aaaagataac
     2281 catatccgcg gacaggcgcg tttttgcccg cataagcggt tgaataatgc ctttatgctc
     2341 catgcttcta ccagcccgtt ctacccgctg tttgccgcgc tggacgttaa tgccaaaatt
     2401 catgaagggg agagtgggcg tcggctgtgg gctgagtgcg ttgagttggg tattgagtcg
     2461 cgcaaggcta ttcttgcgcg ctgtcagctg ttccgcccgt ttatcccgcc cgttgttgat
     2521 ggcaaattgt ggcaggatta tccgacatct gtgttagcca gcgaccgccg ttttttcagt
     2581 tttgagccgg gggcgaagtg gcacggcttt gaaggatatg ctgcggatca gtattttgtt
     2641 gatccgtgca agctgttact cactacacca ggtatcaatg ccgaaaccgg cgaatatagc
     2701 gactttggcg ttccggcgac gattctggcg cactatctgc gtgagaacgg cattgtgccg
     2761 gagaagtgcg atctcaactc cattctgttc ttattaactc cggcggaaag ccacgagaag
     2821 ctggcacaac tggtagcgat gttggcgcag tttgaacagc atattgagga tgactcgccg
     2881 ctggctgagg tgttgccgag cgtttataac aaatatccgg tgcgctatcg cgactacacc
     2941 ctgcgccagt tgtgtcagga gatgcacgat ctgtatgtca gtttcgacgt caaagaccta
     3001 caaaaagcga tgttccgcca gcagagtttc ccgtcagtgg tgatgaaccc ccaggatgcg
     3061 catagcgctt atattcgcgg tgaagtggag ttggtgcgga ttcgtgatgc cgaagggcga
     3121 attgcggcag aaggggcgtt gccttatcca cctggcgtgc tttgcgtggt acccggggaa
     3181 gtctggggtg gggcggttca acgttatttc cttgcgctgg aagaaggcgt gaatttgttg
     3241 ccgggatttt cgccggagtt gcaaggtgtc tatagcgaaa ccgatgcgga tggcatgaaa
     3301 cgattgtacg gttatgtgtt gaagtaagaa taaaaaaacg ggtcaccttc tggcgacccg
     3361 tttttctttg cgtaattagt ggctaaccgt ctgtgtgcct gtcgggacac gaacgtgttt
     3421 atatttgaac atcgccatga acgcgaaggc cagaaccacg gaataaccag cgaaaatcaa
     3481 ccatacggtc tgccagtcgg taatgccgtt ttgggtgtac atctcaacaa ctttaccgct
     3541 cacgatgccg ccgaggatac agccgaagcc gttagtcatc atcaggaaca tcccttgtgc
     3601 actggcgcga attgccgggc taacttcttt ttcgacaaac accgaaccag agatgttgaa
     3661 gaagtcgaat gcgcaaccgt aaacgatcat cgacagtacc agcagtacag taccgaacgg
     3721 agtcgggtcg ccgtaagcaa acagcgcaaa acgcaggatc cacgccacaa tactgatcat
     3781 cattacgttc ttaataccgt agcggcttaa gaagaacggg atggtcagaa tgaacagggt
     3841 ttcagagatc tgcgaaatcg acatgatgat tgacgcatgc tgcacgatga agctgctggc
     3901 aaacatcgga tctttgtcga agctgtgcag gaaggtatta ccgaacatgt tggtaatctg
     3961 cagttccgcg cccagcagca ttgagaagat gaagaagatg gccatacgct tgtttttaaa
     4021 cagcgcgaat gcatcgaggc ccagcagggt tgtccagctc tgattcgctt gctgtttagc
     4081 aaccggaata tgcggcagag tcagggtaaa cagaaccaga atggcggaaa gagctgcgcc
     4141 aatatacagc tgcatgtggc ttaattcgaa gccagacagg ctcaccaccc acattgccat
     4201 gataaagccg atggtgcccc agatacggat tggcgggaag tcagtaacga tatccatccc
     4261 ggcattttgc aggcgatagt aagagatggt gttgattaac ccaagcgttg gcatataagc
     4321 aaacgagtta atcaatatca caaggaacat cgcctccggt gtcgtgacct gtgccgccat
     4381 gaacagcgtg atagcgccaa tggtgtggca aatggcatat acccatttcg cacttaacca
     4441 tttgtcggcc acaatcccca gcagcgcagg cataaagacc gctgcgatac ccagtgagct
     4501 ataaactgcg ccaatagaag caccgtcaaa cttcagggta acaaacatat aggaaccgag
     4561 ggtcgtcagc caacttcccc acagacagaa ctgcagaaaa gagaggattt tcagctgcag
     4621 cttaagattc atgttaattt cctcacatcg tgatgcggat gagtgtttga aaaagcacat
     4681 ttgaccgtgc gagatgatgg gattctatca acttcgcgga ctggtttttt gttacctgtg
     4741 gcaaataatt gcaaacattc ccaatttgca aaatgaaatt gtgatgtgga taacattttt
     4801 gcccctgagc atcgtcaggg gcggttaatg gaattatcgg cggcggtagg atttttgcgc
     4861 ggtattcact ttataaagat aacggcgaga ttccgcagag ggatggcggg tcgtcagcgt
     4921 ctgataaaca tcgcccggcg tcatggtgtt aataatattg gcagcctgaa tcttatcatt
     4981 cgaaaagact cgcagcacgc tgcctgcgcc gccgttatag gcggtgatga cggcataacg
     5041 ccgcgatgtt gggttatcaa ttccgccgag ataaacattg ttcagcatcg ccagatacgc
     5101 ggtgccggta tcaatattgc tggcaggatc aaacaagaaa ctgcggctcg gcgtgccgga
     5161 tttcccctgc gagcggaaca catctttccc ggcagtatgt tgtaccacct gcattaatcc
     5221 cagcgcatcg gaacggctga ccgcatacgg gttaaaggaa gattcggtct gcataattgc
     5281 cagaatcagc gactcatcaa cgccatattt ccgtgacgcc tggcggacca tgccgagata
     5341 tttgtgcgca cgtttatcaa ggtggttcgg taccatgtta atggtgacgc tgtagatgat
     5401 acgcagcccg ttactgcggc tttgcagacg gtttttcagc agataatccg cgaagttgct
     5461 tgcgcgacct tcccagcgaa tcggctgccc ggtgttgtcc accacctgac cgtaaaggaa
     5521 aggttctttc gaaatcgtaa tatcatcaac gtcggaatag agatcgaccg aactcggatc
     5581 gtcacccatc agcaacgttt tgataattgc ccggcgcaaa tgcgcggcag gttctgtccc
     5641 ggcgatagtt tcgatagtaa tcgtaccgtc atcgaagttg atgtggctgc gggtctgata
     5701 ttgatcggtg tatttcacgt agtccttagg accggcgatc accacctctt tgaatcccca
     5761 gatgttctca atattgtggg caaattgccc catcagaata tcaaaaccgt tggtatcttt
     5821 gacccaggct tcgttatagg tatcgccttt tttggtcgtc gaacaggaga tgagcaacgg
     5881 cgcaatcaaa gccagcgcga gatatttttt catcattccg ggtgcgtgtt gtgtttgttt
     5941 ttatgcaagt tgccggaggc gtgctccggc actgttttta ttttttatct tccggcgtat
     6001 agccctcgat atgcacctct ttaccctcga acaggaagtt gaccatctcc tgctcaagca
     6061 gcttgcggtg ctcggcattc atcatgttga gtttcttttc attaatcagc atggtttgct
     6121 tgtgctgcca ctgcgcccag gcttctttgg agatctcgtt atagatgcgt tttcccagct
     6181 cgccggggta cagctgaaaa tcctgacctt ctgcttcacg ttgcaggaaa gtacaaaaaa
     6241 tcgttctgct cataaatcat cctctttatc gactcacgcg ctaaaccggc gcgccagtgc
     6301 gtaattgctg taacaaacgc tccacgggag ccgccaggcc aactgacggc ggttgcgcta
     6361 agttatacca gagcgcattg ccttcatcca tgcagccggt gaatgacgac acgggaagcc
     6421 acataggcac aatatctaag tggaaatggc tgaaggtatg gcgaaacgcg gtcagctgcg
     6481 tcaggttatc ggcagcaatc tgccgttgcg ccagccaatg ccgcaaactt tcttcgtcgg
     6541 caaactgcgg gaaacagtat aaaccgcccc acaatccgct cggcggacgc tgcgccagca
     6601 atacttcatc ttcgtgctgt aatagcaaaa agtagccggt gcgctccggc agcgtctgtt
     6661 tcggtttttt gcccggataa agcgcccagc tattgttggc ggcggcaata catccgtttt
     6721 gtagcggaca gagcgaacat ttcggtttcg agcgcgtaca aatcatcgca cccaaatcca
     6781 tcatcgcctg attaaaccgt tccacgccaa ccgcgggcgt cacctgctcg ctcaaactcc
     6841 ataatttatt ctcgacctct tttttcccag gccagccgct tacagcatag cagcgcgcca
     6901 gcacgcgttt gacgttaccg tcgagaatcg gaaagtgctt acccagagaa agcgagagaa
     6961 tcgctcctgc ggtggaacgc ccgacgcccg gtaacgccgc gacttcttca aaggtttccg
     7021 ggaatttacc gccgtgtaag gtcgccactt gttgtgccgc tttatgcaga ttgcgcgcgc
     7081 gggcgtaata gccaagcccg gtccacaagt ggagaacttc gtcgagcggc gcattggcga
     7141 gatcggtcac cgtcgggaag cgcgccataa agcgttcaaa ataggggata acggtcgcaa
     7201 cctgagtttg ttgcaacatc atttctgaga gccatacttt gtagggcgtc ttgtcaattt
     7261 gccagggcag cgtttttcgc ccgtatttat cgtaccagtc cagaacctgg gctgaaaatt
     7321 gcgacgcttg catggtcacc gaattcactg ttgttggggg caagattgca gcacagcgac
     7381 ggcagggtgt aaaccggaac tttccgcagc cacggcctta tcatgcttgc atccggcaac
     7441 taactttgga taatgcccgt tttcagaaca ctttcacaag cgactaaatc tttatgaaaa
     7501 acgacgtcat ttcaccggaa tttgatgaaa acggccgccc actgcgccgt atccgtagtt
     7561 ttgtgcgccg ccaggggcga ctgaccaaag gccaggaaca tgcgctggaa aactactggc
     7621 cggtgatggg cgttgagttc agcgaagata tgctggattt ccccgcgctt tttggccgtg
     7681 aagcgccggt gacgcttgag attggttttg gcatgggggc gtcgctggtg gcaatggcta
     7741 aagatcgccc tgagcaggac ttcctcggca ttgaagtgca ttcaccgggc gttggtgcgt
     7801 gcctggcttc tgcgcatgaa gaaggtttaa gcaacctgcg agtgatgtgt cacgatgcgg
     7861 ttgaagtgct gcataaaatg attcctgaca attcattgcg catggtgcag ctctttttcc
     7921 ctgacccgtg gcacaaagcg cgccataata aacgccgtat cgtacaggtg ccgtttgccg
     7981 aactggtaaa aagcaaactg cagctggggg gcgtattcca tatggcgacc gactgggaac
     8041 cttatgcgga acatatgctt gaagtgatgt cttctattga cggttataaa aacctgtcag
     8101 agagcaatga ttacgtaccg cgtccggcat cacgtccggt gacgaaattt gaacaacgtg
     8161 gtcatcgtct tggtcacgga gtatgggact taatgttcga gagggtgaaa taatggcaaa
     8221 gaaccgtagc cgtcgtctgc gtaaaaaaat gcacatcgac gaattccagg aattaggatt
     8281 ttcggtggca tggcgattcc cggaaggtac atcggaagaa cagattgata aaaccgttga
     8341 tgattttatt aacgaggtta tcgaaccgaa caaactggcc tttgacggca gcggttatct
     8401 ggcctgggaa ggtctgatct gcatgcagga aatcggcaaa tgcaccgaag aacatcaggc
     8461 gattgtgcgt aagtggctgg aagagcgcaa actggatgag gtacgcacca gcgaactttt
     8521 cgacgtttgg tgggactaag aaagcatacg ggcgatgaca aatgcaaaac tgcctgatgc
     8581 gctacgctta tcaggcctgg aaagatgcac gatcgagtag gcgggataag gtgtttacgc
     8641 cgcatccggc atggaaaacg cgtactttgt tatcaatctg gggccagcaa atgctggcct
     8701 gattttttct tgagggaaga ctatgatgcg caaaatgctg ctggcggcag cactttcagt
     8761 gacggcaatg accgctcacg ccgactacca gtgcagcgtc acgccgcgtg acgatgtgat
     8821 tgtcagcccg caaaccgtgc aggtgaaggg cgaaaacggc aatctggtga tcacgccaga
     8881 cggcaacgtg atgtataacg gtaagcaata ttccctgaat gccgcccagc gcgagcaggc
     8941 gaaggattat caggctgaac tacgcagcac gctgccgtgg attgatgaag gcgcgaaaag
     9001 ccgcgtcgaa aaagcccgta ttgcgctgga taaaattatc gttcaggaga tgggcgaaag
     9061 cagcaaaatg cgcagccgtc tgaccaaact tgatgcgcag ctgaaagagc agatgaaccg
     9121 cattatcgaa acgcgcagcg atggcctgac gtttcactat aaagccattg atcaggttcg
     9181 cgccgaaggc cagcaattag tgaatcaggc aatgggtgga attttacagg acagcattaa
     9241 tgaaatgggc gcgaaagcgg tgctgaaaag cggcggtaac ccattacaga atgtgctggg
     9301 aagcctgggg gggctgcaat cctcaatcca aaccgagtgg aaaaagcagg aaaaagattt
     9361 ccagcagttt ggcaaagatg tttgtagccg cgttgtgact ctggaagata gccgcaaagc
     9421 cctggtcggg aatttaaaat aatcctctat tttaagacgg cataatactt ttttatgccg
     9481 tttaattctt cgttttgtta cctgcctcta actttgtaga tctccaaaat atattcacgt
     9541 tgtaaattgt ttaacgtcaa atttcccata cagagctaag ggataatgcg tagcgttcac
     9601 gtaactggag gaatgaaatg gagtttttca aaaagacggc acttgccgca ctggttatgg
     9661 gttttagtgg tgcagcattg gcattaccca atatcaccat tttagcaacc ggcgggacca
     9721 ttgccggtgg tggtgactcc gcaaccaaat ctaactacac agcgggtaaa gttggcgtag
     9781 aaaatctggt taatgcggtg ccgcaactaa aagacattgc gaacgttaaa ggcgagcagg
     9841 tagtgaatat cggctcccag gacatgaacg ataatgtctg gctgacactg gcgaaaaaaa
     9901 ttaacaccga ctgcgataaa accgacggct tcgtcattac ccacggtacc gacacgatgg
     9961 aagaaaccgc ttacttcctc gacctgacgg tgaaatgcga caaaccggtg gtgatggtcg
    10021 gcgcaatgcg cccgtccacg tccatgagcg cagacggtcc attcaacctg tataacgcgg
    10081 tagtgaccgc agctgataaa gcctccgcta atcgtggcgt gctggtggtg atgaacgaca
    10141 ccgtactgga cggtcgcgat gtcaccaaaa ccaacaccac cgacctagcg accttcaagt
    10201 ctgttaacta cggtcctctg ggatacattc acaacggtaa gattgactac caacgtaccc
    10261 cggcacgtaa gcacaccagc gatacgccat tcgatgtctc taagctgaat gagctgccga
    10321 aagttggcat cgtttataac tacgctaacg catccgatct tccggctcaa gcactggtag
    10381 atgcgggcta tgatggcatc gttagcgctg gtgtgggtaa tggtaacctg tataaatccg
    10441 tgttcgacac cctggcaacc gccgcgaaaa acggcactgc agtagtgcgt tcttcccgcg
    10501 taccgacggg tgctaccact caggatgctg aagtggatga tgcgaaatac ggcttcgtcg
    10561 cctctggcac gctgaacccg caaaaagcgc gcgtcctgct gcagctggct ctgacgcaaa
    10621 ccaaagatcc gcagcagatc cagcagatct tcaatcagta ctaatcacct cgccccggta
    10681 tcgtgccggg gctttttcac ttcagactta cgtccattgc caattttcat taccctaatg
    10741 ataatcaccg gaataaatta ttccgcgtga ggtttttcgg gtgaaaaagc aatggattgt
    10801 tggcacggca ctgcttatgt tgatgactgg taatgcctgg gcagatggcg aaccgccaac
    10861 tgaaaatatc ttaaaagatc aattcaaaaa gcagtatcac ggcattctca agcttgatgc
    10921 tatcacctta aaaaatcttg atgctaaggg taatcaggcc acctggtcag cggaaggcga
    10981 tgtctcttcc agtgacgatc tctatacctg ggtcggtcag ttggcagatt acgaactgct
    11041 cgaacagacc tggacgaaag ataaaccggt aaaattctcg gcgatgttaa ccagtaaagg
    11101 aacgcccgcg tctggctggt cggtgaactt ttactctttt caggcggcag ccagcgatcg
    11161 tgggcgggtg gtcgacgata tcaaaacgaa taataaatat ctgatcgtga atagcgaaga
    11221 tttcaattat cgctttagtc agcttgaatc tgcgttgaat acccagaaga actcgattcc
    11281 tgcgctggaa aaggaagtga aagcgcttga taagcaaatg gtggcggcgc agaaagcagc
    11341 ggatgcatat tggggaaaag atgcaaacgg taagcaaatg acccgcgaag aagcctttaa
    11401 aaaaattcac caacagcgtg atgagtttaa taaacagaac gatagcgagg cgttcgcggt
    11461 taaatatgac aaagaggttt atcaaccggc gattgcggca tgtcataaac agagtgaaga
    11521 gtgttatgaa gtgccgattc agcagaaacg agatttcgat atcaacgaac aacggcgaca
    11581 gacttttctg caatcacaaa aactcagccg taaattgcag gatgactggg taacgctcga
    11641 aaaagggcaa tatccgttaa cgatgaaagt ttcagaaata aacagtaaaa aagtcgcgat
    11701 tttgatgaaa attgacgata tcaaccaagc taatgaacgc tggaaaaaag ataccgaaca
    11761 actgcggcgc aatggggtga ttaagtaagt ttgatatagt gcctttgccg gataatataa
    11821 aaagttatcc ggcaaattat tttttacatt agccctagta gctgtggaat gaacaaggat
    11881 atttgcggaa tgtaagtgat catcatcaac gctactagca atgcagcata aaatggcagc
    11941 aatggtttga ttaaatgttg aatcttcaca cccgagatag aacaaccaac aaatagcgca
    12001 ctacccaccg gcggtgttaa cagcccaata caaaggttgg ccaccatcat aataccgaaa
    12061 tgtactgggt ccattcccag ctcttgtgca atcggcaaga agatcggtgt aaagattagt
    12121 acagccggtg tcatgtccat aaagatgccg acaattaata agacgatatt aatcagcagc
    12181 aatatgatca gtgggttatc agaaatcccc atcaatgcgt cgctgatcat ataaggaata
    12241 tcagcattag tcattgccca ggacatgccc acggaaaaac cgatcaacag taatacaatc
    12301 gaagtggtaa caaccgactc cagaatcagt ttgggtaaat ggcgccattt tacttcccgg
    12361 taaatcagca ccgagagaat aaatgtgtag acaacggcaa ttgctgacgc ttcagttgcg
    12421 gtaaaaatac cgcccagaat gccgcccatc acaatgaaca ccagaagcaa acttggtaag
    12481 gcatccagaa acgctttaca ggcctgagca aaggttgctc tttctgaaag cgggtagcca
    12541 cggcgtttag caataatgcc gcagactatc attaccgcaa gacccattaa gatccctggc
    12601 aaatatcccg ccataaatag cgatgctaca gaaacgccgc cagctgtcag ggaaaacaca
    12661 attaacacgt ttgagggcgg tatcagtaat ccagtaatac aagatgagac gtttacagcg
    12721 gtagaaaatg ccggatcata accttgtttg gtctgaatgg gattcagtgt gccaccaacg
    12781 gcagcagctg ccgcaacggc tgaaccagaa atggaaccaa acatcatatt cgccaggacg
    12841 ttcacatgac caagtgaacc aggaacccga ccaaccatta cctgggcgag gttaatcaaa
    12901 cgtatcgcaa taccgccgct gttcatcagc gttccggcaa agatgaaaaa ggggattgcc
    12961 aatagggcaa agttatccag tccattagcc agtcgctgcg aaacagtgat tgccgcgata
    13021 tcccagggaa acatcaaaag cattgaagct acagtggcaa taccgattga gaacgaaatg
    13081 ggcacaccaa taaagaccaa cacaaaaaaa cagccaaaca gtgtaatcgc gatataacta
    13141 tccattaact ggcctcctgc gcatgttgtt tcagttgttg aatgctttga ttaataaaac
    13201 acaaggcata aaacatcatc accaatccac ttaatggcag aatgatatat acgtatccca
    13261 tcggtatttg catcgcggca gatacctgtg atgttgccag cgttttatca attaatttca
    13321 ggccaccagt cacaatgacc gaaccggcaa aacctaaaat aagaacgtta atgactatac
    13381 taagaagtaa ttgcttgcgc ttattcaggg cgagagcaaa taaatcgata gagagatgtc
    13441 tctgcgcgcc gacggtatat gcagcaccta ataaccctac ccagatcatc aaaaatcgtg
    13501 ccagctcatc ggttaatgta cttggctggt taagtacgta gcggctaaat acttgccaga
    13561 ctacgcatac aaccagagca agcatgacgg cgacagaaaa cgcggcaatg acgcggtcta
    13621 ccgcaagttt caggcggtta aatatcattg taagcatcct ggaaaatcag ggccagagac
    13681 tggcccggaa tattattgag cagcgttgtc gaacttctct aacaaagcag cttgttttgg
    13741 atcttttttg aagtcgtcaa acagaggctg aactgcggca cggaatggtg ctttatccac
    13801 ttttacaatt tcacccccca tagctttcgc ctgagcacgt gtgtcagcgt caattttttc
    13861 ccacaatttt tgttgataag cttcggattt cttcgttgct gtttcgagga tttgttgctg
    13921 ttctggggtt aatttattcc atgttttggt ggagataacc aaaaagtcag gaattgaggc
    13981 gtgttcatct tcagaaaaaa ctttggcaat ttcaatatgt cgagtctgca cccaggaagg
    14041 cacgttattt tctgcgccat ctactacacc ttgctgcatc gcagtataaa cttcgccaaa
    14101 tgaaattgga gtgggtgaac cacccatcag ttcaatcatt ttgatggtgg tcggacttgg
    14161 ctgaacacga attttcagcc ctttaagatc ttctggctta gtaatcggtt ttttcgcata
    14221 gaaactgcgt gtacccgcta cataagctga taaagcaaaa aagcctttgt cttttgttga
    14281 gtccataatt tctttaccaa cttcaccaaa aacaactttg ttgaagtgag cctgatcttt
    14341 aaataagaac ggcaaattat agatagcata aatattatca aaagactcca gatcactggc
    14401 ggaacctttg gtcatatcca gagcgccatt ttgcaacaac tccatagttt ctcgcgcatt
    14461 acccatctgg ctgctgggat aaatacggat caccatatta ccttttgaca gctgttttac
    14521 ctctttcgcc agctcttcaa aactctgatg tacaacatga cttctttcca ggttgtgtgc
    14581 taactttaac gtcacttttt ctgcggcgtt tacgccagtg ctaaccagag tcagcaagga
    14641 tgcgcagact aatgagcggg taaatgacct cattttcata aaaaaactcc ctgttgaagg
    14701 atggaaattg gttgatatct aattgtgctt atcagtgctt tgtgcgacaa attggttaac
    14761 ctgtctgaca acttgtctat gtttatcaca acttgaaata aagtcagaaa ttaaatatta
    14821 aatttgtgcg ccaggttgta ca
//
LOCUS       DAZUDJ010000095        14751 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.095, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000095 DAZUDJ010000000
VERSION     DAZUDJ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14751
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.095"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..603
                     /locus_tag="ACHY1N_004304"
     CDS             <1..603
                     /locus_tag="ACHY1N_004304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046508.1"
                     /translation="DFLNGDPDQPIIMGRTYHQENRTPGSLPGTKTQMTIRSKTYMGS
                     GFNELKFDDATGREQVYIHAQKNMDTEVLNDRTTTVKHDHRETVKNDQTVTIQEGNRL
                     LTVEKGHKITGVLKGSLSEDVFQDRSTIAGSVHVDAVNNGGEGDGIQAYTAIKEILLA
                     VEESKIALTPDGIQLQVGESTVIRLSKDGITIVGGSVFIN"
     gene            631..1092
                     /locus_tag="ACHY1N_004305"
     CDS             631..1092
                     /locus_tag="ACHY1N_004305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcrB-related protein"
                     /protein_id="HFS4046509.1"
                     /translation="MQFTFNEGHIQLPSQWQDQSMQVLVSTDNSGINLVITREAVPQG
                     TLTPELYQETLALYQGKLDGYTEHACREITLAEAPAWLLDYSWNGPEDEGNQGRISQI
                     AVFQRRGDTLLTFTFSTSLSLKNSQKTMLLEVIKSFTPLPPENDIQKDQPR"
     gene            1112..3019
                     /locus_tag="ACHY1N_004306"
                     /pseudo
     CDS             1112..3019
                     /locus_tag="ACHY1N_004306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308632.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
     gene            3161..4297
                     /locus_tag="ACHY1N_004307"
     CDS             3161..4297
                     /locus_tag="ACHY1N_004307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1-like element ISEc1 family transposase"
                     /protein_id="HFS4046510.1"
                     /translation="MEFKKLMEHISIIPDYRQAWKVEHKLSDILLLTICAVISGAESW
                     EDIEDFGETHLDFLKQYGDFENGIPVHDTIARVVSCISPAKFHECFINWMRDCHSSND
                     KDVIAIDGKTLRHSYDKSRRRGAIHVISAFSTMHSLVIGQIKTDEKSNEITAIPELLN
                     MLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNP
                     EHDSYAISEKSHGREEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKE
                     PEMTVRYYISSADLTAEKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFS
                     GIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVLAGSGLS"
     gene            4566..6803
                     /gene="nrfB"
                     /locus_tag="ACHY1N_004308"
     CDS             4566..6803
                     /gene="nrfB"
                     /locus_tag="ACHY1N_004308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-3',5'-guanylate-activated
                     glycosyltransferase NrfB"
                     /protein_id="HFS4046511.1"
                     /translation="MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRR
                     IKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNETGVIGNMAELAATTLDYENYHI
                     FVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
                     AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSEL
                     HGKDVPVREALAGQVPSAGVGTCFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKE
                     KGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTFSTAVRQKSRWIIGI
                     VFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMLQLLLLLAYESLWPDAWH
                     FLSIFSGSAWLMTLLWLNFGLMVNRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFM
                     ANWRALKQVLQHGDPRRVAWDKTTHDFPSVTGDTRSLRPLGQILLENQVITEEQLDTA
                     LRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAEMPASVA
                     LHYAVLPLRLENDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYA
                     RRRGHDPRAMLYNAVQHQWLTEQQAGEIWRQYVPHQFLFAEILTTLGHINRSAINVLL
                     LRHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVSMQSLLLKAGLNTEQVAQLES
                     ENEGE"
     gene            6790..9762
                     /gene="nfrA"
                     /locus_tag="ACHY1N_004309"
     CDS             6790..9762
                     /gene="nfrA"
                     /locus_tag="ACHY1N_004309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage adsorption protein NfrA"
                     /protein_id="HFS4046512.1"
                     /translation="MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRH
                     FVIYPRLDKALKAQKNNDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARL
                     LLEDQLKRHPGDARLERSLAAIPVEVKSVTTVEELLAQQKACDAAPTLRCRSEVGQNA
                     LRLAQLPVARAQLNDATFAASPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLS
                     AAERRQWFDVLLAGQLDDRILALQSQGIFTDPQSYITYATALAYRGEKARLQHYLNEN
                     KPLFTTDAQEKSWLYLLSKYSANPVQALANYTVQFADNRQYVVGATLPVLLKEGQYDA
                     AQKLLATLPANEMLEERYAVSVATRNKAESLRLARLLYQQEPANLTRLDQLTWQLMQN
                     EQSREAADLLLQRYPFQGDARVSQTLMARLASLLESHPYLATPAKVAILSKPLPLAEQ
                     RQWQSQLPGIADNCPAIVRLLGDMSPSYDAAAWNRLAKCYRDTLPGVALYAWLQAEQR
                     QPNAWQHRAVAYQAYQVEDYATALAAWQKISLHDMSNEDLLAAANTAQAAGNGAARDR
                     WLQQAEQRGLGNNALYWWLHAQRYIPGQPELALSDLTRSINIAPSANAYVARATIYRQ
                     RHNVPAAVSDLRAALELEPNNSNIQAALGYALWDSGDIAQSREMLEQAHKGLPDDPAL
                     IRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLTPEQNQQRFNFRRLHEEVGRR
                     WTFSFDSSIGLRSGAMSTANNNVGGAAPGKSYRSYGQLEAEYRIGRNMLLEGDLLSVY
                     SRVFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFLAVEQQLPLNGQNGASDTMLRA
                     SASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTADYRVSWHQKVANGQT
                     IEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVSLGVEYQHTFKAI
                     NQRNGERNNAFLTIGVHW"
     gene            9763..10653
                     /gene="ybcH"
                     /locus_tag="ACHY1N_004310"
     CDS             9763..10653
                     /gene="ybcH"
                     /locus_tag="ACHY1N_004310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4434 family protein"
                     /protein_id="HFS4046513.1"
                     /translation="MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLM
                     SQLRLQGFDTLVLQWTRYGDAFTQPEQRALLFKRAAAAQQAGLKLIVGLNADPEFFMH
                     QKQSSAALESYLNRLLAADLQQARLWSAAPGVTPDGWYISAEIDDLNWRSEAARQPLL
                     TWLNNAQRLISDVSAKPVYISSFFAGNMSPDGYRQLLEQVKATGVNVWVQDGSGVDKL
                     TAEQRERYLQASADCQSPAPASGIVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCG
                     KDTLYFSLRYLPVAHGILEY"
     gene            10836..11597
                     /gene="envY"
                     /locus_tag="ACHY1N_004311"
     CDS             10836..11597
                     /gene="envY"
                     /locus_tag="ACHY1N_004311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator EnvY"
                     /protein_id="HFS4046514.1"
                     /translation="MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNV
                     IELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAA
                     NHSKQQPSKPCEAELTRVLLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
                     HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQ
                     LCGYSSTSYFISVFKAFYGLTPLNYLAKQRQKVMW"
     gene            12110..13063
                     /gene="ompT"
                     /locus_tag="ACHY1N_004312"
     CDS             12110..13063
                     /gene="ompT"
                     /locus_tag="ACHY1N_004312"
                     /EC_number="3.4.23.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease OmpT"
                     /protein_id="HFS4046515.1"
                     /translation="MRAKLLGIVLTTPIAISSFASTETISFTPDNINADISLGTLSGK
                     TKERVYLAEEGGRKVSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMV
                     DQDWMDSSNPGTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYS
                     FTARGGSYIYSSEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTF
                     KYSGWVEASDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRV
                     TNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF"
     gene            13250..14734
                     /locus_tag="ACHY1N_004313"
     CDS             13250..14734
                     /locus_tag="ACHY1N_004313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4046516.1"
                     /translation="MRKIITHFKVVLTLLLPVTVSAQQIQWQSCMASQFNHWFGEEKP
                     SPDLLCGYLSVPLKYTDTGGDASYEKKSQVKLALTKLPAKSKHKGSILIISGGPGLPG
                     INPYINFDWPVTNLRESWDIIGFDPRGVGQSTPTINCRQSDTETQENITEKQQVLNKI
                     NACIHNTGAEVIRHIGSNEAVYDIDRIRQALGDKQLTAVAYSYGTQIAALYAERFPYN
                     VRSIVLDGVVDIDDLEDNFTWQLKQAQSYQETFDRFASWCARTKSCPLSSDRDKAITQ
                     FHELLSKLHHKPLLDSKGENISSDELISLTTDLLLWRSSWPTLATAIRQFSQGIVSNE
                     IETALSAPIASEESSDASGVILCVDQGDEQLTPEERKSRKDALANAFPAINFDNGRSD
                     SPDFCELWPIHSDLNKTRLKNTVLPSGLLFVAHKYDPTTPWINARKMAEKFSSPLLTI
                     NGDGHTLALTGVNLCVDKAVVHYLITPQKIENIYCPGNSEAEIQ"
BASE COUNT         3982 a         3648 c         3706 g         3415 t
ORIGIN      
        1 gacttcctca acggcgatcc ggaccagccg atcattatgg ggcgcaccta ccaccaggaa
       61 aaccgcaccc ccggcagcct gccgggaaca aagacgcaga tgaccatccg ctccaaaacg
      121 tacatgggca gcggatttaa tgagctgaag tttgatgatg cgacagggag agaacaggtc
      181 tacatccacg cgcagaagaa catggatacc gaagtgctca acgaccgtac caccaccgta
      241 aaacacgatc accgcgaaac cgtaaaaaat gaccagacgg tcacgatcca ggaaggtaac
      301 cgccttctta cggtggaaaa aggccacaag atcaccggag tactgaaagg gtctttatct
      361 gaggatgtct ttcaggacag aagcacgatt gccggttcgg tgcatgttga cgctgtaaac
      421 aatggtggcg aaggcgacgg tatacaggct tatacggcga ttaaggaaat tttgctggcc
      481 gtggaggaaa gcaaaattgc gctgacgccg gatggcattc agctacaggt cggggaatcg
      541 acggtaatca ggctgtcgaa ggatggcatc accatcgtgg gcggttctgt tttcatcaac
      601 tgattcactc agattatcag ggagtatttt atgcagttca cttttaatga aggccacatt
      661 caactgccgt ctcaatggca ggatcagtca atgcaggtcc tggtgtccac agataacagt
      721 ggcatcaacc tggtcattac ccgcgaagcc gttccacagg gaaccctgac accagagctg
      781 taccaggaaa cgctggcgct gtaccagggc aaacttgatg ggtacaccga acatgcctgc
      841 cgggaaatca ctctggcaga ggccccggcc tggctgctgg attattcctg gaacggtccg
      901 gaagatgagg ggaatcaggg gcggattagc cagatagccg tattccagcg gcgtggagat
      961 acgctgctga ccttcacttt cagcacctcc ttatccctga agaacagtca aaagacgatg
     1021 ctgctggagg tgataaagag cttcaccccg ttgccaccgg agaatgacat ccaaaaggac
     1081 cagccgcgct gacataaacg agggataaca catgagtgaa ggaccaggcg ggccacaggg
     1141 agcgaccgca ggcggtacgc tggcaatgcg aatgctgtca cagcaggcga tggtcgccag
     1201 ccagatgaaa cgggcagcca acgacaaagc cattgcacag atgctggcag caaagaagtc
     1261 cggcccacct gccgccaggc tgggcgatga aattcagcat aaaagttttc tgggggcact
     1321 ggcaggggcc gtgctggggg cgatagtgac catcgcagaa ggttgcctga ttatggccgc
     1381 ctgcgccacc ggcccttatg cgctggttct ggtgcctgcg ctgatgtatg ccagctataa
     1441 ggcgagtgat tatgtggagg agaaacagaa ccagcttgaa tcatggataa acagcttttg
     1501 tgacacggac ggcgccatca ataccggttc tgaaaatgta aacattaacg gaaagcccgc
     1561 tgcaagggcc gccgtcaccc ttccccctcc tcccccacct ggagcaatac ctgaaatccc
     1621 acagggggaa ccctcatggg gtgatattgc cactgacctg cttgaatcgg cagcggaaaa
     1681 agcagtacca ctggcgaagg cctgggggaa cgctgttatc accctgacgg aaagcaatgc
     1741 cggttttatg gatcgcgtca gcgccggcgc atcgcttctg tttcccgccg gtccggtatt
     1801 aatggagttt gccaccatgg tgggcgggcg tggcgaaatc aaaaaagagg tggatttccc
     1861 ggaagccggt gaggacacgg cgctctgcga caaggagaac aaaccaccga ggatagccca
     1921 gggcagtagc aacgtcttta tcaacaatca gcctgccgcg cgcaagggcg acaaactgga
     1981 gtgcagtgcg gcgatcgtgg aaggttcgcc ggacgtcttt attgggggtg agcaggtcac
     2041 ctatctggat atccagccgg agttcccgcc atggcagaga atgatcctgg gaggaataac
     2101 gatagccagc tatcttctgc cgccagcagg actgctggga aaactgggga atctggcgaa
     2161 actgggcaaa ctgggaaacc tgctggggaa aagcgggaag ctgctgggcg caaagctcgg
     2221 cgcgttgctg gggaaaacag gtaagtcgtt aaaaagtatt gccaataaag tcatcagatg
     2281 ggtaacagat cctgtcgatc cggtaaccgg cgcgtactgc gacgaacgta ccgacttcac
     2341 cctgggccag accctccccc tctccttcac ccgtttccac agttctgtac tgccgctgca
     2401 tggcctgacg ggcgtgggct ggagcgactc ctggagcgaa tacgcctggg tgcgtgaaca
     2461 gggaaaccgg gtggatatca tcagccaggg agccacgctg agatttgcct tcgacggtga
     2521 cagtgatacg acggttaacc cgtatcacgc ccagtacatt ctgcgccgcc gcgatgatta
     2581 tctggagctg ttcgacaggg atgcactgag cagccgcttc ttttatgacg cctttccggg
     2641 aatgcgtctg cgccacccgg tgactgacga taccagcgat gaccgcctgg cacacagccc
     2701 caatgaccgg atgtacatgc tgggcgggat gagcgacacc gccagcaacc gcatcacgtt
     2761 tgagcgcgac agccagtacc ggatcacggg tgtcagtcac accgacggga tccggcttaa
     2821 actgacgtac cacgccagcg gctacctgaa agccattcac cgcacggata acggcataca
     2881 gacgctggcg acctacgaac aggatgcgcg ggggcggctg accgaagcgg atgcgcggct
     2941 ggactaccac ctgttttatg agtacgacgc tgcggaccgg atcatccgct ggtccgataa
     3001 cgaccagacg tggagccagg gaaagatcat gtaacgccgg ttttttgtac taaataattc
     3061 gcattttatg tttaaaaatt gagatattcc ttattacctg aagctgtttt ttattgctta
     3121 tacatgatca aatactcctt acataattaa ggagaacaaa atggaattta aaaaattgat
     3181 ggaacatatt tctattatcc ccgattacag acaagcctgg aaagtggaac ataaattatc
     3241 ggatattcta ttgttgacta tttgtgccgt tatttctggt gcagaaagtt gggaagatat
     3301 agaggatttc ggggaaacac atctcgattt cttgaagcaa tatggtgatt ttgaaaatgg
     3361 tattcctgtt cacgatacta ttgccagagt tgtatcctgt atcagtcctg caaaatttca
     3421 tgagtgcttt attaactgga tgcgtgactg ccattcatca aatgataaag acgtcattgc
     3481 aattgatgga aaaacgctcc ggcactctta tgacaagagt cgccgcaggg gagcgattca
     3541 tgtcattagt gcgttctcaa caatgcacag tctggtcatc ggacagatca agacggatga
     3601 gaaatctaat gagattacag ctatcccaga acttcttaac atgctggata ttaaaggaaa
     3661 aatcatcaca actgatgcga tgggttgcca gaaagatatt gcagagaaga tacaaaaaca
     3721 gggaggtgat tatttattcg cggtaaaagg aaaccagggg cggctaaata aagcctttga
     3781 ggaaaaattt ccactgaaag aattaaataa tccagagcat gacagttacg caatcagtga
     3841 aaagagtcac ggcagagaag aaatccgtct tcatattgtt tgcgatgtcc ctgatgaact
     3901 tattgatttc acgtttgaat ggaaaggtct gaagaaatta tgcgtggcag tctcctttcg
     3961 gtcaataata gcagaacaaa agaaagagcc cgaaatgacg gtcagatatt atatcagttc
     4021 tgctgattta accgcagaga agttcgccac agcaatccga aaccactggc acgtggagaa
     4081 taagctgcac tggcgtctgg acgtggtaat gaatgaagac gactgcaaaa taagaagagg
     4141 aaatgcagca gaattatttt cagggatacg gcacatcgct attaatattt tgacgaatga
     4201 taaggtattc aaggcagggt taagacgtaa gatgcgaaaa gcagccatgg acagaaacta
     4261 tctggcgtca gtccttgcgg ggagcgggct ttcgtaatct tgccctgcct gctcacctcc
     4321 tccaggcact tccactacat gatgacctga tcggtgccac cactcctctt cactatgacg
     4381 ttaacctccc ctccttgaca ccacgctttt gtctacattc tacgcaaacg gcaactttta
     4441 taaccagtgt aaaaataacg tgccgcaata gtcataccta ttaatggtaa aaagctgtca
     4501 caattcataa aaaaccttaa tatacgccac cctaaacata accagcgtta atgtaaggtt
     4561 tttgtgtgga ctggcttctt gatgtttttg caacctggct ctacggctta aaagtaatcg
     4621 cgataacgtt agcggtcatc atgttcatca gcggactgga cgattttttt attgatgtcg
     4681 tctactgggt acgccgcatt aaacgcaagt tgagtgttta tcgccgctac ccgcgaatga
     4741 gttaccgcga actgtataaa ccagatgaaa aaccgttagc gattatggtt ccggcgtgga
     4801 atgaaacggg cgtcatcggc aatatggccg agctggcggc gaccacgctc gactacgaaa
     4861 actatcatat ctttgttggc acctacccca acgaccccga tactcaacgt gatgttgacg
     4921 aagtgtgcgc tcgctttccg aacgtgcata aggtagtctg cgcgcgtcct ggtcccacca
     4981 gcaaagccga ctgtctgaac aacgtgctgg acgccatcac ccagtttgaa cgtagcgcca
     5041 atttcgcttt tgctggtttt attctgcatg acgccgaaga tgtgatttca ccgatggaat
     5101 tgcgtctgtt caactatctg gtcgagcgta aagatctgat tcagatcccg gtgtatccgt
     5161 tcgaacgcga atggacgcac ttcaccagca tgacttacat tgatgagttt tcagagctgc
     5221 atggcaaaga tgttccggtg cgtgaagccc tcgccggaca agtgcccagc gcaggcgtcg
     5281 gcacctgttt cagccgccgc gccgtgaccg ctctgttagc tgacggtgac ggtattgctt
     5341 tcgacgtgca gagtctgact gaagattacg acattggttt ccgcctgaaa gagaaaggta
     5401 tgacggaaat ttttgtccgt tttccggtgg tggacgaagc caaagaacgc gagcagcgta
     5461 aatttttaca gcacgcacgg acgtcaaaca tgatctgcgt gcgcgaatat ttccccgata
     5521 ccttttcgac tgcagttcga caaaaatctc gctggatcat cggcattgtt ttccagggct
     5581 ttaaaaccca caaatggacc tccagcctga cgctgaacta ctttctctgg cgcgaccgca
     5641 aaggggcaat cagtaacttt gtcagcttcc tcgcgatgct ggtgatgctc cagcttttgc
     5701 tgttgctggc gtatgaaagt ttgtggcccg atgcctggca tttcctttct atttttagcg
     5761 gcagcgcatg gttaatgacc ctgctgtggc taaactttgg cttgatggtt aaccgcatcg
     5821 tgcagcgggt gattttcgtc actggctact acggtctgac gcaggggctg ttatctgtcc
     5881 tgcgtctttt ctggggcaac ctgattaact tcatggccaa ctggcgcgcg ctaaaacagg
     5941 tacttcaaca cggcgatcca cgtcgcgtcg cgtgggataa aacaacgcat gacttcccca
     6001 gcgtgactgg cgatacccgc tcgttgcgcc cgttaggcca aattctgctg gaaaatcagg
     6061 tcatcactga agaacaactc gatacagcac tgcgtaatcg cgtcgaaggt ctacgcttgg
     6121 gcggttcaat gctgatgcag gggctgatta gcgccgagca gctggcacag gcgctggcag
     6181 agcaaaacgg cgtggcgtgg gaatccatcg atgcctggca gatcccgtcc tcgctgattg
     6241 ccgaaatgcc ggcctccgta gcgctgcatt atgcagtact gccgctgcgt ctggaaaatg
     6301 atgagttaat tgtcggcagt gaagatggta ttgacccggt ttcgctggcg gccctgacgc
     6361 gtaaagtcgg acgcaaagtg cgttacgtca ttgttctgcg gggacaaatt gtcacggggt
     6421 tacgtcactg gtatgcacgc cgacgcggtc acgatccgcg ggcaatgttg tacaatgcgg
     6481 ttcagcatca gtggctcacg gaacagcagg ccggtgaaat ctggcggcaa tatgtgccgc
     6541 atcagttcct gttcgccgaa atactgacca cgctcggtca tattaatcgt tcagcaatta
     6601 acgtgttgtt attgcgccat gaacgcagtt ctctgccgct cggcaagttt ttggtcaccg
     6661 aaggcgttat cagccaggaa acgttggatc gcgtcctgac aattcaacgc gaattacaag
     6721 tttcgatgca atcactatta ctcaaagcag gtttaaacac agaacaggtt gcgcaactgg
     6781 agtccgaaaa tgaaggagaa taaccttaat cgcgtcatcg gatggtctgg tttactgctg
     6841 acgtctttat tgagtaccag cgcactcgca gacaatatcg gcaccagcgc agaagagctg
     6901 gggctgagcg attatcgcca ttttgttatt tatccccgtc tcgataaggc gctgaaggca
     6961 cagaaaaata acgacgaagc aaccgccatc cgcgaatttg aatatataca ccagcaggtg
     7021 ccggataata ttccgctgac tttatacctt gcggaagcct atcgccattt tggtcatgat
     7081 gaccgggcgc ggctgttgct tgaggatcaa ctgaaacgtc acccaggaga tgcccgactt
     7141 gagcgcagtc tggcggctat tccggttgaa gtgaaaagcg ttacgactgt tgaagaactg
     7201 cttgcccagc aaaaagcgtg cgacgctgcg ccgaccctgc gttgtcgcag tgaagtcggg
     7261 cagaatgccc tgcggctggc acaattacct gtcgccagag cgcaactgaa cgatgcgacg
     7321 tttgctgcat cgccagaagg aaaaacgctg cgaaccgatc tgctgcaacg ggcaatctac
     7381 ctgaaacaat ggtcccaggc agatacgcta tacaatgaag cacgccagca gaacacatta
     7441 agcgcggcag aacgccgtca gtggtttgac gtgcttcttg ccgggcagct ggacgatcgg
     7501 atcctggcac tgcaatcaca ggggatcttc accgatcctc agtcatatat tacttacgcg
     7561 accgcgctgg cttatcgtgg cgaaaaagca cgcctccagc attatctcaa tgaaaataag
     7621 ccgctgttta ccacggacgc acaagagaaa agttggctct atctgttatc taaatacagc
     7681 gccaaccccg ttcaggcatt ggcgaattat acggtgcagt ttgccgataa ccgccagtat
     7741 gttgttggcg cgacgctacc ggtgctgtta aaagaaggtc agtacgacgc agcgcaaaaa
     7801 ctgctcgcca ccctccccgc caatgaaatg cttgaggagc gttatgctgt cagcgtggcg
     7861 acccgtaaca aggctgaatc tctgcgtctg gcacgattgc tgtatcagca agaaccggca
     7921 aatcttaccc gcctggatca actgacctgg caactgatgc agaacgagca gtcacgcgaa
     7981 gctgccgatt tattgctgca acgctatcct ttccagggcg atgcgcgtgt cagccagact
     8041 ttaatggcgc gactggcgtc tctgctggaa agtcatcctt acctggcaac gccggcgaag
     8101 gtggcgattt tatcgaaacc cttaccgctg gcggagcaac gtcagtggca aagtcagttg
     8161 ccgggtattg cagataattg cccggcaata gttcgcttgc tgggcgatat gtcgccttcc
     8221 tacgatgccg ccgcctggaa ccgtctggca aagtgttatc gggacacgct acccggtgtg
     8281 gcgctgtatg catggcttca ggccgaacaa cgacaaccga acgcctggca acatcgtgcg
     8341 gtagcctatc aggcgtatca ggttgaggac tacgccaccg cactggcggc ctggcagaaa
     8401 atcagtcttc acgacatgag caatgaggat ctgcttgctg ctgccaatac cgcccaggcg
     8461 gcaggaaatg gtgcagctcg cgatcgctgg ctacaacagg cagaacaacg tggactggga
     8521 aacaatgccc tctactggtg gctgcatgcg caacgttaca ttcctggtca gccggaactc
     8581 gcactgagcg atctcacgcg ctcaatcaat attgcccctt ctgccaacgc ttacgttgcg
     8641 cgggcgacaa tttatcgcca acgtcataat gtcccggcgg cggtgagtga tttgcgcgcc
     8701 gcgctggaac tggaaccgaa taatagcaac atccaggcag cgcttggtta cgccttgtgg
     8761 gatagcggtg atatcgcaca gtcgcgggaa atgctcgaac aggcgcataa agggcttccg
     8821 gacgatccgg cactgatccg acaactggcc tacgtgaacc agcgtctgga tgacatgcct
     8881 gcgacgcagc actacgcccg gctggtgatt gatgacattg ataatcaggc gctgataacc
     8941 ccactgaccc cagagcaaaa tcagcaacgc ttcaatttcc gccgtttgca tgaggaggtc
     9001 ggtcgccgct ggacgttcag tttcgattct tctatcggct tgcgttccgg ggcaatgagc
     9061 accgctaaca ataatgtcgg cggcgcagcg ccagggaaaa gctatcgtag ctacgggcaa
     9121 ctggaagccg agtaccgcat cggacgcaat atgctgctgg aaggcgacct gctctcagtt
     9181 tatagccgcg tctttgccga taccggagaa aacggggtga tgatgccggt gaaaaatccg
     9241 atgtccggca ccggtctgcg ctggaagccg ctgcgcgatc agatcttttt cctcgccgtc
     9301 gaacagcagt tgccgctgaa cggccaaaat ggcgcatccg ataccatgct gcgcgccagc
     9361 gcctcattct ttaatggcgg caaatacagc gacgaatggc acccgaacgg ttcaggctgg
     9421 tttgcccaaa acctgtacct cgatgcggcg caatatatcc gccaggatat tcaggcgtgg
     9481 acggcagatt atcgcgtcag ctggcatcag aaggtagcta acggacagac tattgagcct
     9541 tacgctcacg ttcaggacaa cggctatcgt gataaaggca ctcagggcgc gcagcttggc
     9601 ggagtcgggg tccgctggaa tatctggacc ggcgagacgc actacgacgc ctggccgcac
     9661 aaagtcagtc tcggcgtcga gtatcaacat acctttaagg cgattaatca acgtaacgga
     9721 gagcgcaaca acgcgtttct caccattgga gtgcactggt aaatgcgtaa gttcattttc
     9781 gtattgctga cactgctttt ggtcagccct ttttcctttg cgatgaaagg tattatctgg
     9841 caaccacaaa accgagatag tcaggttacc gatacccagt ggcaggggct gatgagtcag
     9901 ttacgtttgc aaggcttcga taccctggtt ttgcaatgga cccgttacgg cgatgcattc
     9961 acccagccag aacagcgcgc gttattgttt aagcgtgccg cagctgcgca acaggctggc
    10021 ctgaagctga ttgtcgggct gaacgccgat ccggaatttt ttatgcacca gaaacagtcg
    10081 tccgcagcgc tggaaagcta tcttaatcgc ctgctggctg ccgatctcca gcaagccaga
    10141 ttatggagcg ccgcgcctgg cgtaacgccg gatggctggt acatcagcgc ggaaattgac
    10201 gacctgaact ggcgcagcga agctgcccgt cagcctttgc taacatggtt aaacaacgcg
    10261 cagcggctga ttagcgatgt ttcagcaaaa ccggtttata tcagtagttt tttcgccgga
    10321 aacatgtcgc ccgatggcta tcgccaactg ctggaacaag ttaaagcaac cggcgttaat
    10381 gtctgggtac aggatggcag cggcgtggat aaacttaccg ctgaacagcg tgaacgttat
    10441 ctacaggcca gcgccgattg ccaaagtccc gcccctgcca gcggcattgt ttatgaactg
    10501 tttgtcgccg gcaaaggcaa aacctttaca gcgaaaccga aaccggatgc agagatcgcc
    10561 tcgctgttag cgaaacgttc ctcttgcggt aaagacactc tctatttctc tctgcgctat
    10621 ttgcccgtcg cgcacggcat tctcgagtat taaatctcct ccaggtaagt cgggtacgac
    10681 ctggcttacc tctttcgctc tcgtcagaat tccatcaaga ttaattgcta aaaagcgtgc
    10741 taaagaaaga agatcgttat cggcgaacgg gccgatcact catgcaggaa gcatagatcc
    10801 tttgagcgga gtttctgata tctgaggagt gcgaaatgca attgagcagc agtgaacctt
    10861 gcgtggtgat cctgaccgaa aaagaggtag aggtaagcgt caataaccat gctacgttta
    10921 cccttccgaa aaactacctg gccgccttcg cgtgcaacaa taacgtcatt gaactctcaa
    10981 cgttaaatca cgtattaatc acccacatca accgtaacat catcaacgat tatctgttgt
    11041 ttttaaataa gaacttaacc tgtgtaaagc cctggtcgcg gctggcaacc ccggttattg
    11101 cttgtcatag ccgtacaccg gaagtgttcc ggctagccgc caaccacagc aagcagcaac
    11161 ccagcaaacc ctgcgaagcg gagttgacgc gcgtattgct ttttaccgta ttgtctaact
    11221 ttcttgagca atcgcggttt attgccctac tgatgtatat cttacgcagc agcgtccgcg
    11281 acagcgtctg ccgcattatt caaagcgata ttcagcatta ctggaatctg cgaattgtcg
    11341 ccagttcgct atgtttaagc cccagcctgc tcaaaaagaa attaaaaaac gaaaatacca
    11401 gctatagcca gattgtcaca gagtgtcgta tgcgttacgc cgtacagatg ttattgatgg
    11461 ataacaaaaa tatcactcag gtggcgcaat tatgtggcta tagcagcacg tcatacttta
    11521 tctctgtttt taaggcgttt tacggcctga caccgttgaa ttatctcgcc aaacagcgac
    11581 aaaaagtgat gtggtgaagg gcaaagcgga aacggataag acgggcataa atgaagaaga
    11641 aatggcgcgc cctgcaggat tcgaacctgc ggcccacgac ttagaagttc ctagaacgac
    11701 attttaagtc aacaaattac cgcgccatct ctgcgctcac acgtcccact acctcaaaac
    11761 atgtaaagcc ttgcaagcca ttgtgaggcc ttatgtgtct cagttttgtc cctctttttt
    11821 gtactaaaaa acatagcaat tgaggataaa cctcatgcta ttttcgctta tatgccttta
    11881 aaggcatggc gcttaaatag ataaaaacac cacaaaagca taaaaaacca cacagtaaaa
    11941 ccgcaacata aaacaataac agataattaa accaaaaaca gatagcgcat tgtgataatc
    12001 attcaatact aaacaaaata taaacagtgg agcaatatgt gattgactca ttaagttaga
    12061 tataaaaaat acatattcaa tcattaaaac gattgaatgg agaactttta tgcgggcgaa
    12121 acttctggga atagttctga caacccctat tgcgatcagc tcttttgctt ctaccgagac
    12181 tatatcgttt actcctgaca acataaatgc ggacattagt cttggaactc tgagcggaaa
    12241 aacaaaagag cgcgtttatc tagctgaaga aggaggccga aaagtcagtc aactcgactg
    12301 gaaattcaat aacgctgcaa ttattaaagg tgcaattaat tgggatttga tgccccagat
    12361 atctattggg gctgcgggct ggactactct cggcagccga ggtggcaata tggtcgatca
    12421 ggactggatg gattccagta accccggaac ctggacagat gaaagtaggc accctgatac
    12481 acaactcaat tatgccaacg aatttgatct gaatatcaaa ggctggctcc tcaacgaacc
    12541 caattaccgc ctgggactca tggccggata tcaggaaagc cgttatagct ttacagccag
    12601 aggtggttcc tatatctaca gttctgagga gggattcaga gatgatatcg gctccttccc
    12661 gaatggagaa agagcaatcg gctacaaaca acgttttaaa atgccctaca ttggcttgac
    12721 tggaagttat cgttatgaag attttgagct aggtggcaca tttaaataca gcggctgggt
    12781 ggaagcatct gataacgatg agcactatga cccaggaaaa agaatcactt atcgcagtaa
    12841 agtcaaagac caaaattact attctgttgc agtcaatgca ggttattacg taacacctaa
    12901 cgcaaaagtt tatgttgaag gcgcatggaa tcgggttacg aataaaaaag gaaatacttc
    12961 actttatgat cacaatgata acacttcaga ctacagcaaa aatggtgcag gcatagaaaa
    13021 ctataacttc atcactactg ctggtcttaa gtacaccttt taacgaagtt aaccagattt
    13081 tctccccggt ggtattgtat aaccccgggg aatttgttta cagttacaag taggcaatat
    13141 ccactaattt tgtaagcatt taacctatgt cataacgtgt aatctcttac cgcaacacaa
    13201 gacctcaata tattcaaatc ttatctttat tccgatattc agagacacaa tgcgaaaaat
    13261 aattactcat ttcaaagttg ttttaacgtt acttctacca gtaaccgtat ctgcccagca
    13321 gatacagtgg caatcctgta tggccagtca attcaaccac tggtttggtg aggaaaaacc
    13381 gtctcctgac ttactatgtg gttatttgtc tgttccatta aaatatacag acacaggcgg
    13441 agatgcttct tatgaaaaaa aatcacaagt caaactagcg ttgacaaaat tgccggcaaa
    13501 aagcaagcat aaaggaagta tcctgataat aagtggtggt cccgggttac caggcataaa
    13561 tccttatatt aactttgact ggccagtcac aaatcttcgt gagtcatggg atattattgg
    13621 atttgatcct cgaggcgtcg gacagtccac tccgacaata aactgccggc aatcagatac
    13681 agagactcag gaaaacataa ccgaaaagca acaagtatta aataaaatta atgcctgtat
    13741 ccataatacc ggagccgaag tcattcgcca tatcggctct aacgaggctg tatacgatat
    13801 tgatcgtatt aggcaagcct tgggggataa acaactgaca gccgtggcgt attcgtatgg
    13861 aactcaaatt gcagccttat atgcagaacg ttttccctac aacgtaagat ctatcgttct
    13921 tgatggagtc gtcgatatcg atgacctgga ggacaacttc acatggcaac tcaaacaggc
    13981 acagagttat caggaaacgt ttgatcgctt tgcatcctgg tgtgcgcgta caaaaagttg
    14041 cccgctttct tcagacagag ataaggcaat aactcagttc catgagctat tatcaaaatt
    14101 acatcacaaa cctttattag acagtaaggg agaaaatata tcttcagatg aactcatatc
    14161 attaacaaca gaccttctgc tatggcgttc atcatggcca acccttgcaa ctgccatacg
    14221 ccagttctct caggggattg tcagtaatga aattgaaact gcgctcagtg ctccgatagc
    14281 ctcagaagag tcaagcgatg cttcgggggt aatcctctgt gtagatcagg gggatgagca
    14341 attaacacca gaagagcgaa aatcccgaaa agacgctctt gcgaatgcct tcccggctat
    14401 taactttgac aatggacgtt ccgattcacc tgatttttgt gaattatggc caatacatag
    14461 cgacctgaac aaaactcgcc tgaaaaatac tgttctgccc tctggtttac tgtttgtagc
    14521 acacaaatac gacccaacaa cgccctggat taatgcccgt aagatggcag agaaattctc
    14581 cagcccgtta ctaacaataa atggtgatgg gcatacatta gctctcaccg gagttaattt
    14641 atgtgtagat aaagcagttg tacattacct gatcactcca caaaaaatag aaaatatata
    14701 ctgcccagga aattctgaag cagaaataca ataatttcaa aatattccgc t
//
LOCUS       DAZUDJ010000096        14599 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.096, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000096 DAZUDJ010000000
VERSION     DAZUDJ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14599
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.096"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..245)
                     /gene="cdiI4"
                     /locus_tag="ACHY1N_004314"
     CDS             complement(<1..245)
                     /gene="cdiI4"
                     /locus_tag="ACHY1N_004314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDI system immunity protein CdiI-o11"
                     /protein_id="HFS4046517.1"
                     /translation="MAFNKDQDYWANIFVTPDFLSVETYSGLGMTGRDPLFSPRLLQP
                     DVDDKSLGEEILQALSDSRTLDVLEERVAFFDLEKSK"
     gene            complement(245..1135)
                     /locus_tag="ACHY1N_004315"
                     /pseudo
     CDS             complement(245..1135)
                     /locus_tag="ACHY1N_004315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000245723.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1134..1352)
                     /locus_tag="ACHY1N_004316"
     CDS             complement(1134..1352)
                     /locus_tag="ACHY1N_004316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000611256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046518.1"
                     /translation="MINVLFALFSILAGGILAEIAYIFLIIIEYAMVGSFNFDLTSAW
                     LYFKAAGVEGGIMGIGISLFRYFGVKGF"
     gene            complement(1349..3379)
                     /locus_tag="ACHY1N_004317"
     CDS             complement(1349..3379)
                     /locus_tag="ACHY1N_004317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFS4046519.1"
                     /translation="MNIRIRSGMLPCMDISALNTTNDIEKLRAMALAMVQKVMSENAE
                     KERELLEKSRRIQLLEEMLKLVRQQRFGKKCETLAGMQRSLFEEDVDVDIAELTAHLD
                     KLLPQSPEEDEKASRSRPIRKPLPAHLPRVEKIIQPDTDHCPECDEPLHYIRDAVSEK
                     LEYIPAHFVVNCYVRPQYSCPCCQKVFSGEMPAHILPKSAVEPSVIAQVIINKYGEHL
                     PLYRQQQVFARSDVGLPVSSMADMVGAAGAALSPLAALLHRELISRPVVHADETTLKI
                     LNTKKGGKSCSGYLWAYVSGERTGPSVVCFDCRTGRSHEYPENWLQGWGGTLVVDGHK
                     AYRTLANKVPELANIIGHHAGIDDNTAAKAIAHAILGGVTAALQGNSAAAGAIGAGTG
                     EVISSAIAKSLYPDVDPSKLTEDQKQTVSTLATLSAGMAGGIASGDVAGTAAGAGVGK
                     NIAENNLVGGTESEQSKAAQTHGADVLSCNDAPGGEACKRGEAVNKAYAGALATGSVA
                     LLPGGAQAMWALGTGANAGIGYMVDSSVDPENAIIAGWVNVITMGQGWKGTVGWNAAG
                     GALGNWIDDKDPLSGALINGTGSGIGYGVGKGLSWGVNAGENWWKGGWDPKFNSELRS
                     VTKVKGDYGLSKEMKPSKVPSSFGDVGGSAFSEITGKGIEKISSSNANGDKK"
     gene            complement(3386..3778)
                     /gene="tnpB"
                     /locus_tag="ACHY1N_004318"
     CDS             complement(3386..3778)
                     /gene="tnpB"
                     /locus_tag="ACHY1N_004318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258751.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFS4046520.1"
                     /translation="MLSPDNVFIAIKPVDMRRGIDTLTQYIQDELRSTWHEGAAFVFV
                     NKDRSRIKVLRWDKHGVWLCTRRLHKGSFRWPRANDAAWHLTPDEFNWLIAGVDWQQV
                     KGHGLTKWVWQNEPELRPENTQNTLLTH"
     gene            complement(3765..4094)
                     /locus_tag="ACHY1N_004319"
     CDS             complement(3765..4094)
                     /locus_tag="ACHY1N_004319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFS4046521.1"
                     /translation="MSKPRWTIEQKRQHVAAWRASGLTRQQYCELNDIPFTSLREWPQ
                     DVAKAERRANEPTVLPVHIAPPLHADVPQPVTNEPVTLFLPGGVRMCCQPSQLTDVFR
                     ALKYAQS"
     gene            complement(4184..4640)
                     /locus_tag="ACHY1N_004320"
                     /pseudo
     CDS             complement(4184..4640)
                     /locus_tag="ACHY1N_004320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309404.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(4643..4920)
                     /locus_tag="ACHY1N_004321"
                     /pseudo
     CDS             complement(4643..4920)
                     /locus_tag="ACHY1N_004321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_046881606.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(5281..6189)
                     /locus_tag="ACHY1N_004322"
     CDS             complement(5281..6189)
                     /locus_tag="ACHY1N_004322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4046522.1"
                     /translation="MANWAQKLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLS
                     QLEDEIGITLFERHSKGLRPTEGGKLLLQHAQRLINDMERSQHELARFKQGGLVGSLK
                     IGCSPVATDCVSQAILHLLTKMPTLHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRAL
                     QLPLNYQVLYTEPVCFVASPEHPLAKYATLSWNDLANWRWIVWPTGTPIRISIDNALV
                     DHGVMLPENTIESASMNVSTNLLQSSDMISILSLRLAQRYASQGQLVILNLPKIEQKG
                     SVGVFWRNNETPSYALSQFLHFLQQN"
     gene            6316..7674
                     /locus_tag="ACHY1N_004323"
     CDS             6316..7674
                     /locus_tag="ACHY1N_004323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4046523.1"
                     /translation="MTQRRDLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFI
                     APDIRTHWQLTAGDLAPLFGAGLLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSL
                     ASAFSPDLQTLVFLRFLTGLGLGGAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSA
                     VGGIVSAQLVPVIGWHGILVLGGVLPLMLFVALLVVLPESPRWQVRRQLPQAVIAKTV
                     SAITRERYVDTQFYLIESASVTKGSIRQLFMGRQLPITLMLWVVFFMSLLIIYLLSSW
                     MPTLLNHRGIDLQHASWVTAAFQIGGTLGALALGVLMDKFNPFRVLALSYATGAICIV
                     MIGLSQDGLWLMALAIFGTGIGISGSQVGLNALTATLYPTQSRATGVSWSNAVGRCGA
                     IVGSLSGGVMMAMNFSFDTLFFIIAVPAAISAVMLTLLITVVRQSTSIPDSLPHAGVV
                     NE"
     gene            7686..8714
                     /gene="gtdA"
                     /locus_tag="ACHY1N_004324"
     CDS             7686..8714
                     /gene="gtdA"
                     /locus_tag="ACHY1N_004324"
                     /EC_number="1.13.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047922 - gentisate 1,2-dioxygenase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gentisate 1,2-dioxygenase"
                     /protein_id="HFS4046524.1"
                     /translation="MTDNNQNSREQFYQHISGQNLTPLWESLHHLVPKTPNANCAPAY
                     WNYQEIRPLLLESGSLIGAKEAVRRVLVLENPALRGQSSITATLYAGLQLIMPGEVAP
                     SHRHNQSALRFIVEGKGAFTAVDGERTPMNEGDFILTPQWRWHDHGNPGDEPVIWLDG
                     LDLPLVNTLGCGFAEDYPEDQQPVTRKEGDYLPRYAANMLPLRHQTGNSSPIFNYRYD
                     RSREVLHDLTRMGDADEWDGYKMRYVNPVTGGYPMPSMGAFLQLLPKGFSSRVARTTD
                     STIYHVVEGSGQVTIGNEIFTFSAKDIFVVPTWHGVSFQTTQDTVLFSFSDRPVQEAL
                     GLFREARY"
     gene            8730..9431
                     /locus_tag="ACHY1N_004325"
     CDS             8730..9431
                     /locus_tag="ACHY1N_004325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HFS4046525.1"
                     /translation="MTQYVFEPQAPVTVPVVGSDKQFPVRRVYCVGRNYAAHAREMGF
                     DPDREPPFFFCKPADAVIPVAAGETLALPYPAQTDNYHYEIELVVAIGKKGSDIPLEH
                     AHEYVWGYATGLDMTRRDRQMEMRQMGRPWEIGKAFDLSAPIAPLHKARDIGGIDNAP
                     IWLQVNGEDHQRSDIRHLIWSVNETISYLSGFFELQPGDLIFTGTPEGVGPVVKGDVI
                     TGNVEGLTPIAVKIV"
     gene            9440..10084
                     /gene="maiA"
                     /locus_tag="ACHY1N_004326"
     CDS             9440..10084
                     /gene="maiA"
                     /locus_tag="ACHY1N_004326"
                     /EC_number="5.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311055.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016034 - maleylacetoacetate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maleylacetoacetate isomerase"
                     /protein_id="HFS4046526.1"
                     /translation="MKLYSFFNSSASYRVRIALALKGINYQTEGVNIRIGQQNELAYR
                     RMNPVGLVPTLLTDEGQSLGQSLAIIDWLERHYPQVPLVPQEEPARNKVLEIVYAIAC
                     DIHPLNNLRVLRYLTEELNVSEEEKKRWYAHWIQQGLSAVEQLLRQNQSGQFCVGETP
                     TLADCCLVPQWANALRMNCDLSGYPRCKAVYDACTQLPAFIAAAPENQQDKISA"
     gene            10099..11292
                     /locus_tag="ACHY1N_004327"
     CDS             10099..11292
                     /locus_tag="ACHY1N_004327"
                     /EC_number="1.14.13.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybenzoate 6-monooxygenase"
                     /protein_id="HFS4046527.1"
                     /translation="MTKVTRAVIVGGGIGGAATALSLARLGIKVVLLEKAHEIGEIGA
                     GIQLGPNAFSALDSLGVGEVARQRAVFTDHITMMDAVNAEEVVRIETRQAFRDHFGGP
                     YAVIHRVDIHASVWEAVLTHPDVEYHTSTNVVDIRETEDDVTVFDDRGNSWTGDILIG
                     CDGVKSVVRQSLLGDAPRVTGHVVYRAVIDCADMPEDLRINAPVLWAGPHCHLVHYPL
                     RGGTQYNLVVTFHSRQQEEWGVKDGSKEEVLSYFEGIHPRPRQMLDKPTSWRRWSTAD
                     REPVAKWGTNRITLVGDAAHPVAQYMAQGACMALEDAVTLGKALAQCEGDAAQAFALY
                     ESVRIPRTARIVWSTREMGRVYHAAGVERQVRNLLWKGKSQAEFYRGMEWLYGWKEDN
                     CLQPR"
     gene            11642..11782
                     /locus_tag="ACHY1N_004328"
     CDS             11642..11782
                     /locus_tag="ACHY1N_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001645505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046528.1"
                     /translation="MPPHKIRQEWLALDETAEVILQHSITLQSADLIRHSFIWRNRSI
                     CL"
     gene            12007..13164
                     /locus_tag="ACHY1N_004329"
     CDS             12007..13164
                     /locus_tag="ACHY1N_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046529.1"
                     /translation="MAVIWFYLSNIDRLDIFFDTVSLSSAIGIIFVFIIVSFSGFSLV
                     IFISSFILILIYTLHEDNFKNYPSIPHRISTVCYLNSLFICCSIIVGYYIYYLYGWNG
                     YSISITGFVLMLAFSYFASYFNLFKTKRFSWHKSDNYEKLPRKPGLLCFLPLQFMTPG
                     IVQILPMLFLLTQLDFSEETSDLVEMLMLLALTAAIVTIGILPGAIHLNERRNGDKFT
                     GFIVVLICIPVVITVFSMWYRPIPNMIINMVMSLSGISDWRTHQYYIENKTHSHSMFN
                     GLIWNTRHYTEIPERFFITGVSTFTLGDIKLVCPTEITEARKESLKFTINDINEYEQK
                     GKQLKAVAMKCIPFNKNDIHTWDSPLSEPIYYEKVKQTIDNSMLKILHTLK"
BASE COUNT         3482 a         3775 c         3524 g         3818 t
ORIGIN      
        1 tctttacttt tttcaagatc gaaaaaagct actcgctctt ccaaaacatc tagtgtacgg
       61 ctgtcagaca atgcctgtag gatctcctca cctaggcttt tatcatctac atcaggctgt
      121 aataaacgtg gtgaaaacaa tggatctctg cctgtcattc ctaatcctga ataagtttca
      181 acactcaaaa aatctggtgt aacaaatata ttcgcccagt aatcctgatc tttattaaaa
      241 gccattattt cacctgcgtt accgtcactt tgacgccctg agatttaccg tactcaatag
      301 ccctgtttat ttctgcccac tgtgttttag ttgtgtcagc aggaatagcg agctgtatct
      361 ccctgttaga gatcattgat gaagttaatt ctcgcccaga gagtgcatat tctttaaact
      421 tagccgcagc atcgatgttt ccttttatcg aactgtaaac ctgattcgga ttagccaatt
      481 tcgccatagt ttgcgtatcc attgatttta cactggtagc agttttggta gcaccatcat
      541 agtaatcaaa ggtcttaaag ttctttggta aacgggcatc agcggaaaga gatttcccaa
      601 cataatcctc ccacagcata ccctgtttca tatttccctg ttcccactgc attccaactt
      661 ctgttgcttt gaccgtcgca gtcgctgtat tgcgactcat gaatgatata gccgctttgg
      721 ttttatcttt taccagtaaa cctccgctga ccagcatggc tgattttcag gatcggaagc
      781 aaacactgca aacttcgtcc attcagggct gtttacatct atttttgcca gatcccggcc
      841 attccactgc tgaacatagg ctttggcttc atcactggtc attacttccg caccaatgtt
      901 acccagccaa ccagggcgct gcgtcatatc atatccgccc ttcgcaactt ccttatcaat
      961 aatctgggct cccagcggat tgtctttcag cttctgatcg atttctgcgc tctgttcatc
     1021 actgattttc ttccatttat cgataacatt ctgacagttc cccccggaat tccgatagca
     1081 ccttgtcaaa agtcagagac tgctcttcac taaggtaatt attctcaaca tcattaaaat
     1141 cctttaactc caaaatatcg aaatagagaa attcctattc ccattatacc tccttctact
     1201 cccgcggcct taaagtacaa ccatgctgat gtcaagtcaa agttaaaact accaaccatt
     1261 gcgtactcaa taataattaa aaaaatgtaa gcaatctcag ctaaaatccc ccctgccaaa
     1321 attgaaaata acgcgaaaag aacattgatc atttcttatc tccattagca tttgaagacg
     1381 aaattttttc gattcctttt cctgttattt cggagaaagc agaaccacct acgtcaccaa
     1441 atgagctagg aactttgctt ggtttcattt cttttgaaag accataatcc cctttaactt
     1501 tagtaacact tctcaactca gaattaaact tcggatccca accacctttc caccagtttt
     1561 cccctgcatt aacaccccat gaaagtcctt tgccaactcc ataaccaata cccgaaccgg
     1621 taccattgat aagggcacct gacaatggat ctttgtcgtc aatccagtta cccagcgcac
     1681 cacctgccgc attccaccca acggttcctt tccagccctg ccccatggtg attacattga
     1741 cccatcctgc aatgattgca ttttcaggat caactgaact atctaccatg taaccaattc
     1801 ctgcatttgc acctgtgcca agagcccaca tggcctgagc accgccaggt aagagagcta
     1861 cactaccagt ggccaacgct ccggcatacg ctttattgac tgcttctcct cgcttacagg
     1921 cttcaccgcc tggagcatcg ttacaggaaa gtacatctgc gccatgcgtc tgagcagctt
     1981 tgctctgctc ggactctgtg ccaccaacca agttattctc agcaatgttc ttcccaacac
     2041 cagcccctgc agctgtgcca gccacatcgc cactggcaat gccgccagcc atacccgctg
     2101 acagcgttgc cagcgtgctt acggtttgct tctgatcttc tgtcagtttc gacggatcta
     2161 cgtccgggta gaggcttttc gcaatggctg acgagatcac ttcaccagta cccgcaccaa
     2221 ttgcgcctgc tgccgcactg ttgccctgaa gggctgctgt cacaccaccg agaatggcat
     2281 gggcaatggc ttttgccgct gtattgtcat caatacccgc gtgatgaccg atgatattcg
     2341 ccagctccgg cactttgttt gccagagtcc ggtaagcttt atgtccgtcg acaaccagcg
     2401 tcccgcccca gccctgaagc cagttttcag gatactcatg gctacgtccg gtccggcagt
     2461 cgaagcacac aactgacggt cccgtccttt ctccactgac gtatgcccac agataaccgg
     2521 agcaggattt accgcctttc ttcgtgttca ggatcttcag ggtagtctca tctgcatgca
     2581 ccaccggacg gcttatcaat tcgcgatgga gtaacgccgc gaggggggat aatgcggccc
     2641 ctgccgcgcc aaccatgtca gccatcgaac tgacgggcag tccgacatct gaacgggcaa
     2701 agacctgttg ctggcgatac agaggcaggt gctcaccgta tttattgatg atcacctgtg
     2761 cgatgactga tggctcaacg gcacttttcg ggaggatatg tgccggcatt tcaccgctga
     2821 acaccttctg gcaacaggga caactgtatt gcggacggac ataacagttc accacaaagt
     2881 gagcgggaat atactccagc ttttcactca ccgcatcacg gatatagtgc agcggctcgt
     2941 cacattcagg gcaatggtca gtgtccggct ggataatttt ttccacccgt ggaagatgag
     3001 ccggtaaggg tttgcgtatc gggcgtgaac gggacgcttt ttcgtcttct tcaggggatt
     3061 gcgggagcag tttatccaga tgtgcggtga gctcggcgat atcgacatca acatcctctt
     3121 cgaacaggga gcgttgcata ccagccagcg tttcacattt tttaccgaag cgctgttgac
     3181 gaaccagttt cagcatttct tccagaagct ggatgcgccg gcttttctcc agtaattccc
     3241 gctctttttc ggcattctcc gacatgactt tttgtaccat ggcaagtgcc atagcacgca
     3301 gtttttcgat gtcattcgtg gtgttgagag cggagatatc catacagggg agcataccac
     3361 tccggatacg aatattcatt atttttcagt gagttagcag tgtgttttgc gtgttttcag
     3421 ggcgcagttc aggttcattt tgccagaccc atttcgtcag gccatgtccc ttaacctgct
     3481 gccagtcaac accggcaatc agccagttaa actcgtcggg agtgaggtgc caggcagcat
     3541 catttgcacg tggccagcgg aagctgcctt tgtgaagacg gcgggtacac aaccacaccc
     3601 cgtgtttatc ccaccggaga actttgatac gcgaacggtc tttgttaaca aagacgaagg
     3661 cggctccctc atgccatgtc gaccggagtt catcctgtat atactgcgtc agtgtgtcga
     3721 tgccccggcg catgtcaaca ggtttaatcg cgatgaagac attatcagga ctgagcatat
     3781 ttgagcgccc tgaagacatc ggtaagttgt gacggctgac agcacatccg tactccgccg
     3841 ggaaggaaga gcgtgactgg ctcattcgtg acgggctgtg gtacatcagc atgcagtggt
     3901 ggcgcaatat gaacgggaag aacggtcggt tcatttgccc ggcgttcagc ttttgcgaca
     3961 tcctgcggcc attcgcgaag tgatgtgaag ggaatatcgt tgagttcaca gtattgctga
     4021 cgtgtaagac cactggcgcg ccaggcagca acgtgctgcc ttttctgttc aatggtccat
     4081 cggggttttg acatcgatta tctccggtaa gttggtgaat gaatgtcggt aatactaact
     4141 gactgaagat ccctgtgaag atgacttccc cgtaacgaca cagaatatct tccgcaatac
     4201 gctgactacc agaccagaac agaccgtcca gtgcggtcac cagtaatccc tcctctagcg
     4261 catacttaag tcattcacgg agcgctttca ctttccgggc aatctgctgc caaggcgatg
     4321 atgtatttca ttcccaacca tccggcgaat acggtgagac agatgatacc ggaatgtatc
     4381 cgcacgccgg aaagactggc cttcaggcta tacacgcaac caaagcgttt atcgttaaac
     4441 accacatttt tctggctgat atcccattct tcccaaagca cagcaatcag ctgtgacgtg
     4501 cgggttaaaa gcagacgaaa aggcagttca aaactggtgg tataatccac attcagcagg
     4561 gcattacgca gccgctctcc tgatccgacc tctgcctgcc gacactcctc ctgaacatcc
     4621 tgccactgct ggcgaaggcg tacaacaaca cgaacattct cagcgtattt ttttgagtaa
     4681 ccaactgaaa aatggtggga agatcatttt tcagttgaga attccccaac ggtcaatcca
     4741 cccgctttat cttgttttta actaatgctg tctggttaaa tgacgcccga tgctgctaag
     4801 cgtgagggaa gcgccattta ttacagcatt tgttgcgtca atcagtgatt tttgatggta
     4861 gaaatgcaaa gtggccagta tgtttttaag gaatttttgg cataatgaac gtgcaggcat
     4921 agtggtgata tccttgaaat tgctagcaca atcaattaga tcacatctca ctatgcctgt
     4981 cttgttttct gggaattcct aatgggttgt ccttccaatt ggttctttcg aggcctgctc
     5041 agattcactc acattatgac ctgtatactc actgaaacac ctacagcttc ttcatcaaat
     5101 acatcagccg ctttgttacc cacacgactg ctttgactgc taccggctgg aacgacagtc
     5161 acctggtggg attttcaccc catgaaagat cacgccttat cacagtgcac gattccccga
     5221 aaaattacgc atcgttgaat tacagggaag taacatcgtg cgaatgccca gttcagcaca
     5281 ctaattctgc tgtaaaaagt gcagaaactg acttaaagca taagaaggcg tttcgttatt
     5341 gcgccagaac acaccgacgc tgcctttctg ttctatcttt ggcaggttga gtatcaccag
     5401 ttgtccctgg ctggcataac gttgcgccag gcgtaatgac aaaatagaga tcatatcgct
     5461 gctttgtaac aggttggtac tgacgttcat cgacgccgac tcaatcgtgt tttctggcag
     5521 cattacgccg tggtctacca gcgcattatc aatactaatg cgaatggggg tacccgtcgg
     5581 ccagacgatc cagcgccagt tggcaagatc attccaactg agggtggcgt atttcgccag
     5641 tgggtgctca gggctggcga caaagcatac tggctcggtg tacagcacct gataattcag
     5701 tggcagttgc aaggcgcgac cgccaattcg cccaacgacc acgtcgacag aacctgccaa
     5761 cagatcttgc agcaatgggg tcatcacctt ctcttcgata ttcaggtgta gagttggcat
     5821 cttcgtaagc aaatgcaaaa tcgcctggga tacgcagtca gtggcgacgg gagaacagcc
     5881 aattttcaga ctgccgacca gtccaccttg tttaaaacgg gccagttcat gttgcgatcg
     5941 ctccatgtca ttgattaacc gttgggcatg ttgcaataac aatttgccgc cttcagtcgg
     6001 acgtaatcct ttgctgtgcc gctcaaaaag tgtgattcca atctcatctt cgagttgtga
     6061 caaccatttc gaaagcgcag gttgggtgat attcatcatt cgtgcgacat gggtcagatt
     6121 gccctgttca cccaacgcca ccagcatttc aaggtgatgt agttttaatt tttgcgccca
     6181 gttcgccatt taccataacc tccaggttat ctctctgccc gaaatgccat tgtacatttc
     6241 atctctttaa tcacaatatc gcaacatata caaaacaaaa gaaacatcta ccttacctgc
     6301 actgaggcat ttactatgac tcaacgacgt gatctacaag cacttatcga tgctgctccg
     6361 gtcggcaaga tgcagtggcg cgttatcatc tgctgttttc tggtggtaat gctcgatggt
     6421 tttgacaccg cggctatcgg atttatcgcc cctgatattc gcactcactg gcaactcacc
     6481 gcaggcgatc tcgccccgct ttttggcgcg ggtctgctgg ggttaaccgc aggcgcactg
     6541 ctttgtggcc cgttgtccga tcgctttggt cgcaagcggg tgattgagct gtgcgtcttt
     6601 ttgtttggcg cgttaagcct cgcctcagct ttctctccgg atctgcaaac tctggtcttc
     6661 ctgcgctttc tcaccggctt gggtctgggc ggcgcgatgc cgaacaccat caccatgacc
     6721 tcggaatatc tgcctgcccg ccgccgcggc gcgctggtga cgctgatgtt ttgcggcttt
     6781 accctgggtt cggcggttgg cgggattgtc agcgcgcagc tggtgccggt gattggctgg
     6841 cacgggatcc tggtgttggg tggcgtatta ccgctgatgc tgtttgttgc actgctggtg
     6901 gttctgccgg aatcgccacg ctggcaagtg cgccgccagc taccccaggc ggtgattgcg
     6961 aaaaccgtca gcgccatcac ccgcgagcgt tatgtcgata cccagtttta tctcattgaa
     7021 tcagcctccg ttacaaaagg cagcattcgt caactgttta tggggcgtca gttacccatc
     7081 acgttgatgc tgtgggtggt gttctttatg agcttgctga ttatttacct gctctcaagc
     7141 tggatgccaa cgctgctcaa ccatcgcggc atcgacctgc aacatgcctc ctgggttacc
     7201 gccgcgttcc agattggcgg tacgttgggc gcgctggcgc tgggcgtgct gatggataag
     7261 ttcaatcctt tccgcgtact ggcgctgagc tatgccacag gcgctatatg catcgtgatg
     7321 attggcttaa gccaggatgg attatggctg atggcgctgg cgattttcgg caccggcatt
     7381 ggcatcagcg gatcgcaggt ggggctgaat gcgctgaccg caacacttta tccaacacaa
     7441 agtcgcgcca cgggcgtgag ctggtcaaac gccgtgggcc gctgcggcgc gattgttggc
     7501 tcgctgtctg gcggcgtgat gatggcgatg aatttctctt tcgacaccct gtttttcatt
     7561 atcgctgtgc ctgcggcgat cagtgcggtg atgttaaccc tgctgatcac cgtggttcgc
     7621 cagtcgacct ctatccctga ctcactgcct cacgcaggtg ttgtgaacga ataaggagca
     7681 tcccaatgac tgataacaat caaaatagcc gtgaacaatt ttatcagcat atttccgggc
     7741 aaaacctgac cccgctgtgg gagtcactgc accatctggt gccgaaaacg cccaacgcta
     7801 actgtgcgcc agcgtactgg aattatcagg agatccgccc gctgctgctg gagagcggca
     7861 gcctgattgg cgcgaaagag gcggtgcgcc gcgtgctggt actggaaaac ccggcgctgc
     7921 gagggcagtc ttccatcacc gcgactttat atgccggttt gcaactgatc atgccgggcg
     7981 aagtggcacc gagtcatcgt cataaccagt cggcgctgcg ttttattgtt gaaggcaaag
     8041 gggcatttac cgccgttgac ggcgaacgca cgccaatgaa tgagggcgat tttatcctga
     8101 ccccgcagtg gcgctggcac gatcacggca accctggcga cgaaccggtt atctggctcg
     8161 atgggttgga tctgccatta gtgaacactc tgggctgcgg ttttgccgaa gattacccgg
     8221 aagatcaaca accggtaacg cgtaaagagg gcgattacct gccgcgttac gctgccaata
     8281 tgttgccgct gcgccatcag acggggaact cctcgccgat ctttaactat cgttatgacc
     8341 gcagccgcga agtgctgcac gatttaaccc gcatgggcga tgccgacgaa tgggatggct
     8401 acaaaatgcg ctacgtcaac ccggtcaccg gcggctatcc gatgccgtcg atgggcgctt
     8461 tcctgcaact gctaccgaaa gggttctcct cccgcgtggc gcgcaccact gacagcacta
     8521 tctaccatgt agtggaaggt agcggacaag tcaccatcgg caatgaaatc ttcaccttta
     8581 gtgcaaaaga tatctttgtg gtgccgacct ggcacggcgt gtcattccag actacgcaag
     8641 ataccgtttt attcagtttt tcggacagac cggtacaaga agccctgggg cttttccgcg
     8701 aagcgcgtta ttaatttggg agagagaaaa tgactcaata tgtattcgaa ccacaagcgc
     8761 ccgttaccgt accggttgtt ggcagtgata aacaattccc cgtgcgtcgc gtttactgcg
     8821 tcgggcgtaa ctatgccgcc cacgcccgcg aaatgggctt tgatccggat cgtgaaccac
     8881 ccttcttctt ctgcaaacca gcagatgccg ttattccggt cgccgctggc gaaacgctgg
     8941 cgctgccata tccggcgcag accgataact atcattacga aattgaactg gtagtggcga
     9001 ttggtaaaaa aggcagcgat atcccgctgg aacacgccca tgaatatgtc tggggttatg
     9061 ccacgggtct tgatatgact cggcgtgacc gtcaaatgga aatgcgccag atgggccgcc
     9121 cgtgggaaat cggtaaagcg tttgatctct cagcgcccat cgcgccgctg cacaaagccc
     9181 gcgatatcgg cggtattgat aatgcgccaa tctggttaca ggttaacggc gaagatcatc
     9241 agcgcagcga tattcgccat ctcatctggt cggtgaatga aaccatcagc tatctgtcag
     9301 gcttctttga gctgcaaccg ggcgatctga tcttcaccgg tacgccggaa ggggttggcc
     9361 cggtagtgaa aggtgatgtg atcacaggca acgtcgaggg cttaacgcct atcgcggtga
     9421 agattgtctg aggtgcatga tgaagctgta cagttttttt aatagttcag cgtcgtaccg
     9481 ggtacgcatt gcgctggcgc tgaaaggcat taattaccag accgaagggg tgaatatccg
     9541 tattggtcag caaaatgaac tggcctatcg gcggatgaat ccggtcgggc tggtgccgac
     9601 gctgctgact gacgagggcc aatcactcgg acaatcgctg gcgattattg actggctgga
     9661 gaggcactac ccgcaagttc cgctggtgcc gcaggaagaa ccggcccgca acaaggtgct
     9721 ggaaattgtc tatgccatcg cttgtgatat tcatccatta aataacttgc gcgtgctgcg
     9781 ctacctgacc gaagaactga acgtcagtga agaagaaaaa aaacgttggt atgcgcactg
     9841 gatccagcaa gggttaagcg cggtggaaca actgttgcgc cagaaccagt cggggcaatt
     9901 ttgtgtgggc gagacgccga cgctggcaga ttgctgcctt gtcccgcagt gggcaaacgc
     9961 gctacgcatg aactgcgatt tgagcgggta tccacgctgc aaagcggtgt acgacgcctg
    10021 cacacagctg ccagcgttca ttgccgcagc gccagaaaat caacaagata aaatttcagc
    10081 ctgaccagga gaactataat gacgaaagtg acacgcgcag taattgtggg aggcgggatc
    10141 ggcggtgcgg caactgcatt gtcactggcc cgcctgggga tcaaagtggt gctgctggaa
    10201 aaggcgcatg agatcggtga gattggcgcg ggcatccagt tggggccaaa tgcgttttcg
    10261 gcgctggaca gcctcggcgt cggcgaagtt gcccgccagc gcgcggtgtt taccgatcac
    10321 attaccatga tggatgcggt gaacgccgaa gaagtggtgc gcattgaaac caggcaggcc
    10381 tttcgtgacc atttcggcgg tccttacgcg gtgatccacc gggttgatat tcacgcctcg
    10441 gtgtgggaag cggtactgac gcatccggac gtggaatatc acacctccac caacgtcgtg
    10501 gatattcgcg agacggaaga cgatgtcacc gtgtttgacg atcgcggcaa tagctggacc
    10561 ggcgatattc tgattggctg tgacggcgtg aagtcagtgg tgcgccagag cttattgggc
    10621 gatgcgccgc gtgtcaccgg acatgttgtc taccgtgcgg ttatcgattg tgccgatatg
    10681 ccggaagatt tgcgcattaa cgcaccggta ctgtgggcgg ggccgcactg tcacctggtg
    10741 cattaccctt tgcgcggcgg cacgcagtat aacctggtgg tgacattcca cagccgccag
    10801 caggaagagt ggggcgtgaa ggatggcagt aaagaggaag tgctctctta ctttgagggg
    10861 attcacccgc gtccgcgcca gatgctggat aaaccgactt catggcgacg ctggtcaact
    10921 gccgaccgtg aaccagtcgc gaaatggggc actaaccgca ttacgctggt gggcgatgca
    10981 gcccatccag tggcgcaata tatggcgcaa ggtgcctgta tggcgctgga agacgcggta
    11041 acgctgggta aggcgctggc gcagtgtgag ggtgatgcgg cgcaagcctt tgcgctgtat
    11101 gagtcggtac gtattccgcg caccgcgcgt attgtctggt cgacccgtga gatgggacgg
    11161 gtttatcacg ccgcgggagt agaacgccag gttcgtaacc tgctgtggaa agggaaatcg
    11221 caggcagagt tttatcgcgg catggagtgg ctgtacggct ggaaagaaga taactgtctg
    11281 caaccacgct gagtacttct tcacctaacc aggcgcacgg gtgatctcct tgcccttcgg
    11341 agaggagcta ttaagtcctg ttgatttcaa cagggctctc tcctctccct ttagcctcct
    11401 ttaaaataag gtatcatcag aaattcttct ttcaacaaat agcacgccac ttcaagcaaa
    11461 tcgtctccag agctattcag tgttacgtcc tgtttttcca gtgtaaatca tcaccagatt
    11521 atgtctgaaa agctcgttac ctacactgat cagtgttagt tgttttggca aaaatatctc
    11581 acaccggttt tcatcatcaa caagcactat acgcaaccaa caacacaaaa aggaacacac
    11641 catgccccca cacaaaatcc gccaggagtg gctggcgctg gacgagaccg cagaagtcat
    11701 cctacagcac agcatcacgt tgcaatccgc cgaccttatc cgccattctt ttatttggcg
    11761 caaccgcagt atctgtctgt gatgttggtg ttactgccaa gcgctttatg gttcgggata
    11821 acggcatgta tggtagcaag tagctttaag cgatggttat aagttgctca aaaaatcggt
    11881 cctcactaca atacgaattt tatcaggtat ggaattcgga ttatgaataa atctgtcata
    11941 aagctgttga ataaaaaatt cattatttca gtaataacct catctacatt tattactgga
    12001 tgcacaatgg ctgttatatg gttctatctg tcaaacatag atagattaga tattttcttt
    12061 gatactgtaa gcctcagttc agccataggt atcatttttg tttttataat agtatcgttt
    12121 tctgggttta gcttagtaat tttcatttcc tcttttattc taatcctcat ttacacatta
    12181 catgaagata atttcaaaaa ttatccaagc ataccacatc gaatttccac tgtttgttat
    12241 ctaaatagct tgtttatatg ctgtagtata attgttggct actatattta ctatctttat
    12301 ggatggaatg gttattccat aagtatcacc ggttttgtat tgatgcttgc ttttagttat
    12361 tttgcatcct attttaatct atttaaaaca aagagattta gttggcataa atctgataac
    12421 tatgagaaat taccaagaaa accaggattg ttatgttttt tacccttgca atttatgact
    12481 cccgggatcg ttcaaatatt acctatgtta tttctgctta cccaacttga ttttagtgag
    12541 gagacaagtg atttggttga aatgctaatg ctccttgcct taacagcagc tattgttact
    12601 attggcattc tgcctggtgc catacatctt aatgagcgca gaaatggtga taaattcact
    12661 ggattcatag ttgttttaat atgcatacca gttgtaatta ctgtattcag tatgtggtat
    12721 cgccctatcc caaatatgat cattaatatg gtaatgagtc tctcaggcat tagtgactgg
    12781 agaacgcatc agtattatat cgaaaataaa actcattctc atagtatgtt taatggctta
    12841 atctggaata ctcggcacta tacagaaatc cccgagagat ttttcatcac cggggtcagt
    12901 acatttacct taggagatat aaagctggta tgcccaactg aaataacaga agcaagaaaa
    12961 gagagtttga aatttaccat taatgatatc aatgagtatg agcaaaaagg gaaacagtta
    13021 aaggcagtag ccatgaaatg cattcctttt aataagaacg atattcatac ctgggattcg
    13081 ccattatctg aaccgatcta ttacgaaaaa gtcaaacaga ccatagataa ctcgatgtta
    13141 aaaattctcc ataccctgaa atgaggtaat gttccgggga agtcatattg acgcgttttt
    13201 agacgcgtca tcagcggtgt atgcggatga tcacggccct gcgatggttg atttatttta
    13261 ttgcgtgtgg gcgtttgcct gacaggcacc gctgccagcg ttattatcgt cgtgttttct
    13321 gtttcgtact ctatttactg atcgtacata tcaggtgcag catcgatatc gtaggatctc
    13381 cttcatcccg atattgcagg ccgccgctgg ctgccgatca ttttgctgtc gctaacgatc
    13441 tcactgattc tgtgggcatg cggcaaattg cccgtttttc tcttctacgt ctttatcgcc
    13501 gccaaattcc cctcaatctc ctgctgttcg tcggtggcgc tggcgtaaaa acgcgcagat
    13561 tattctgacc tcggcggcag cacaccgcta cagttttacc taccgatcgt accggtctgc
    13621 gttatcgctt ttgactttca tggtagcgtt ccctctctga caagaaggtg gcgatttctc
    13681 atacagcccc tcaccacact actccgcatg actggtaata cttcatacgc catgtataac
    13741 aacaatctgc tatacgcacc cttctgctga caacatcccc ctgaatgcct gcacacacat
    13801 cgctgtctgc tgccagtgaa taataatcag cactccctgc ggaatccata aacgacctct
    13861 atcgtatttt cggtgcaaaa cgcaacacac ttgtacgata aaagcacgac ggcttattac
    13921 tgttcccccg gttgactaca tcctcccttt cggtgactta acttattttc attcgattgc
    13981 tccgggcaaa gcctcaacca gaggcgtgtc ccggagggaa taacgtcggt aacggcttag
    14041 caaatgatgc cggccatcac aggaacggcg aacgaaaggc acgtgttttt gaatgccgtg
    14101 aacgactcac tgctttcagg tgtggctgca cacgccccct gtaactgcat accacagtac
    14161 agtgctcgtc agggggtagt gatgccctgg cctgtagcat taactcagcc aggtgcgaat
    14221 cggtttcatc agttctagcc ctagatcccg gtaggtgcat gagatcctga ttgatcagca
    14281 acaggagagc gtattctggt gctttctgta ttttctcgca gccagcgtag taccaccgcg
    14341 gttgccgggc cggctgcgtg agtacgctca gacatgcatc tgttcacctg aagatacgta
    14401 tggaatgacg aggcagcctg tcagtcacag gagggctgtt ggctcaaaat caacggaaag
    14461 gccaccaaca ccggaattaa gctccacagt ccccgcactg gcaatccatt cccgggaacg
    14521 gcatcaccgc aaactgcgcc agaggcaacc attacaacct ctgtaacgga ttatcagccc
    14581 tggcatcttc cgacggcac
//
LOCUS       DAZUDJ010000097        14318 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.097, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000097 DAZUDJ010000000
VERSION     DAZUDJ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14318
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.097"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..73)
                     /locus_tag="ACHY1N_004330"
     CDS             complement(<1..73)
                     /locus_tag="ACHY1N_004330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415090.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046530.1"
                     /translation="MAQVAIFKEIFDQVRKDLNCELFY"
     gene            359..565
                     /gene="ybcW"
                     /locus_tag="ACHY1N_004331"
     CDS             359..565
                     /gene="ybcW"
                     /locus_tag="ACHY1N_004331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YbcW"
                     /protein_id="HFS4046531.1"
                     /translation="MNKEQSADDPSVDLIRVKNMLNSTISMSYPDVVIACIEHKVSLE
                     AFRAIEAALVKHDNNMKDYSLVVD"
     gene            complement(730..924)
                     /gene="ylcI"
                     /locus_tag="ACHY1N_004332"
     CDS             complement(730..924)
                     /gene="ylcI"
                     /locus_tag="ACHY1N_004332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HFS4046532.1"
                     /translation="MSTKNRTRRTTTRNIRFPNQMIEQINIALDQKGSGNFSAWVIEA
                     CRRRLTSEKIAYTSIKSDEE"
     gene            1313..1858
                     /gene="nohD"
                     /locus_tag="ACHY1N_004333"
     CDS             1313..1858
                     /gene="nohD"
                     /locus_tag="ACHY1N_004333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HFS4046533.1"
                     /translation="MEVNKKQLADIFGASIRTIQNWQEQGMPVLRGGGKGNEVLYDSA
                     AVIKWYAERDAEIENEKLRREVEELRQASEADLQPGTIEYERHRLTRAQADAQELKNA
                     RDSAEVVETAFCTFVLSRIAGEIASILDGLPLSVQRRFPELENRHVDFLKRDIIKAMN
                     KAAALDELIPGLLSEYIEQSG"
     gene            1833..3758
                     /locus_tag="ACHY1N_004334"
     CDS             1833..3758
                     /locus_tag="ACHY1N_004334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HFS4046534.1"
                     /translation="MNISNSQVNRLRHFVRAGLRSLFRPEPQTAVEWADANYYLPKES
                     AYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTL
                     IWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFTNGRGFWCLG
                     GKAAKNYREKSVDVAGYDELAAFDDDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVR
                     GTCQIERAASESPHFMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEH
                     NACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPDSVTFHIWTAYSPFT
                     TWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSAPVPDR
                     VAYLTAGIDSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLRVDEAINKTYT
                     RRNGAEMSISRICWDTGGIDPTIVYERSKKHGLFRVIPIKGASVYGKPVASMPRKRNK
                     NGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQLTAEEQV
                     EKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAAT
                     NKKTLADYARALSGEDE"
     gene            3755..3961
                     /locus_tag="ACHY1N_004335"
     CDS             3755..3961
                     /locus_tag="ACHY1N_004335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019058 - viral life cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail joining protein"
                     /protein_id="HFS4046535.1"
                     /translation="MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTATSVSDLK
                     KYIAELEVQTGMTQRRRGPAGFYV"
     gene            3958..5559
                     /locus_tag="ACHY1N_004336"
     CDS             3958..5559
                     /locus_tag="ACHY1N_004336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4046536.1"
                     /translation="MKTPTIPTLLGPDGMTSLREYAGYHGGGSGFGGQLRSWNPPSES
                     VDAALLPNFTRGNARADDLVRNNGYAANAIQLHQDHIVGSFFRLSHRPSWRYLGIGEE
                     EARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTS
                     SSRLFRTQFRMVSPKRISNPNNTGDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQK
                     WTWIPRELPGGRASFIHVFEPVEDGQTRGANVFYSVMEQMKMLDTLQNTQLQSAIVKA
                     MYAATIESELDTQSAMDFILGANSQEQRERLTGWIGEIAAYYAAAPVRLGGAKVPHLM
                     PGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQLSRNYAQMSYSTARASANES
                     WAYFMGRRKFVASRQASQMFLCWLEEAIVRRVVTLPSKARFSFQEARSAWGNCDWIGS
                     GRMAIDGLKEVQEAVMLIEAGLSTYEKECAKRGDDYQEIFVQQVRETMERRAAGLKPP
                     AWAAAAFESGLRQSTEEEKSDSRAA"
     gene            5540..6859
                     /locus_tag="ACHY1N_004337"
     CDS             5540..6859
                     /locus_tag="ACHY1N_004337"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HFS4046537.1"
                     /translation="MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISRLT
                     DAVSGDSLTAQEALATLALSGDDDGPRQARSYQVMNGIAVLPVSGTLVSRTRALQPYS
                     GMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
                     NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHK
                     VDGNPYSHLPDDVRETLQSRMDATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAID
                     AGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSATASQADVTDVVPAT
                     EGENASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVKTAR
                     RILAAAPQSAQARSDTALDRLMQGAPAPLAAGNPASDAVNDLLNTPV"
     gene            6869..7201
                     /locus_tag="ACHY1N_004338"
     CDS             6869..7201
                     /locus_tag="ACHY1N_004338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HFS4046538.1"
                     /translation="MTSKETFTHYQPQGNSDPAHTATAPGGLSAKAPAMTPLMLDTSS
                     RKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGTFRYEDVLWPEAASDETKKRTAF
                     AGTAISIV"
     gene            7257..8282
                     /locus_tag="ACHY1N_004339"
     CDS             7257..8282
                     /locus_tag="ACHY1N_004339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HFS4046539.1"
                     /translation="MSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQI
                     PGLVNMALYVSPIVSGEVIRSRGGSTSEFTPGYVKPKHEVNPQMTLRRLPDEDPQNLA
                     DPAYRRRRIIMQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVEVDMGRSEEN
                     NITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVKEKL
                     DTRRGSNSELETAVKDLGKAVSYKGMYGDVAIVVYSGQYVENGVKKNFLPDNTMVLGN
                     TQARGLRTYGCIQDADAQREGINASARYPKNWVTTGDPAREFTMIQSAPLMLLADPDE
                     FVSVQLA"
     gene            8324..8722
                     /locus_tag="ACHY1N_004340"
     CDS             8324..8722
                     /locus_tag="ACHY1N_004340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HFS4046540.1"
                     /translation="MTKDELIARLRSLGEQLNRDVSLTGTKEELALRVAELEEELDDT
                     DETAGQDTPLSRENVLTGHENEVGSAQPDTVILDTSELVTVVALVKLHTDALHATRDE
                     PVAFVLPGTAFRVSAGVAAEMTERGLARMQ"
     gene            8734..9087
                     /locus_tag="ACHY1N_004341"
     CDS             8734..9087
                     /locus_tag="ACHY1N_004341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HFS4046541.1"
                     /translation="MADFDNLFDAAIARADETIRGYMGTSATITSGEQSGAVIRGVFD
                     DPENISYAGQGVRVEGSSPSLFVRTDEVRQLRRGDTLTIGEENFWVDRVSPDDGGSCH
                     LWLGRGVPPAVNRRR"
     gene            9099..9677
                     /locus_tag="ACHY1N_004342"
     CDS             9099..9677
                     /locus_tag="ACHY1N_004342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4046542.1"
                     /translation="MAIKGLEQAVENLSRISKTAVPGAAAMAINRVASSAISQSASQV
                     ARETKVRRKLVKERARLKRATVKNPQARIKVNRGDLPVIKLGNARVVLSRRRRRKKGQ
                     RSSLKGGGSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAVPLTT
                     AFKQNIERIRRERLPKELGYALQHQLRMVIKR"
     gene            9674..10069
                     /locus_tag="ACHY1N_004343"
     CDS             9674..10069
                     /locus_tag="ACHY1N_004343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail U family protein"
                     /protein_id="HFS4046543.1"
                     /translation="MKHTELRAAVLDALEKHDTGATFFDGRPAVFDEADFPAVAVYLT
                     GAEYTGEELDSDTWQAELHIEVFLPAQVPDSELDAWMESRIYPVMSDIPALSDLITSM
                     VASGYDYRRDDDAGLWSSADLTYVITYEM"
     gene            10077..10817
                     /locus_tag="ACHY1N_004344"
     CDS             10077..10817
                     /locus_tag="ACHY1N_004344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4046544.1"
                     /translation="MPVPNPTMPVKGAGTTLWVYKGSGDPYANPLSDVDWSRLAKVKD
                     LTPGELTAESYDDSYLDDEDADWTATGQGQKSAGDTSFTLAWMPGEQGQQALLAWFNE
                     GDTRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTA
                     ATGMTVTPSSTSVVKGQSTTLTVAFQPEGVTDKSFRAVSADKTKATVSVSGMTITVNG
                     VAAGKVNIPVVSGNGEFAAVAEITVTAS"
     gene            10833..11255
                     /locus_tag="ACHY1N_004345"
     CDS             10833..11255
                     /locus_tag="ACHY1N_004345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HFS4046545.1"
                     /translation="MFLKTESFEHNGVTVTLSELSALQRIEHLALMKRQAEQAESDSN
                     RKFTVEDAIRTGAFLVAMSLWHNHPQKTQMPSMNEAVKQIEQEVLTTWPTEAISHAEN
                     VVYRLSGMYEFVVNNAPEQTEDAGPAEPVSAGKCSTVS"
     gene            11237..11671
                     /locus_tag="ACHY1N_004346"
     CDS             11237..11671
                     /locus_tag="ACHY1N_004346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HFS4046546.1"
                     /translation="MFDGELSFALKLAREMGRPDWRAMLAGMSSTEYADWHRFYSTHY
                     FHDVLLDMHFSGLTYTVLSLFFSDPDMHPLDFSLLNRREADEEPEDDVLMQKAAGLAG
                     GVRFGPDGNEVIPASPDVADMTEDDVMLMTVSEGIAGGVRYG"
     gene            11664..14144
                     /locus_tag="ACHY1N_004347"
                     /pseudo
     CDS             11664..14144
                     /locus_tag="ACHY1N_004347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
     gene            14141..>14318
                     /locus_tag="ACHY1N_004348"
     CDS             14141..>14318
                     /locus_tag="ACHY1N_004348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4046547.1"
                     /translation="MKTFRWKVKPGMDVASVPSVRKVRFGDGYSQRAPAGLNANLKTY
                     SVTLSVPREEATVLE"
BASE COUNT         3334 a         3567 c         4390 g         3027 t
ORIGIN      
        1 aataaaacaa ttcacagttt aaatcttttc gcacttgatc gaatatttct ttaaaaatgg
       61 caacctgagc cattggtaaa accttccatg tgatacgagg gcgcgtagtt tgcattatcg
      121 tttttatcgt ttcaatctgg tctgacctct ttgtgttttg ttgatgattt atgtcaaata
      181 ttaggaatgt tttcaattaa tagtattggt tgtgtaacaa agtgcggtcc tgctggcatt
      241 ctggagggaa atacaaccga cagatgtatg taaggccaac gtgctcaaat cttcatacag
      301 aaagatttga agtaatattt taaccgctag atgaagagca agcgcatgga gcgacaaaat
      361 gaataaagaa caatctgctg atgatccctc cgtggatctg attcgtgtaa aaaatatgct
      421 taatagcacc atttctatga gttaccctga tgttgtaatt gcatgtatag aacataaggt
      481 gtctctggaa gcattcaggg caattgaggc agcgttggtg aagcacgata ataatatgaa
      541 ggattattcc ctggtggttg actgatcacc ataactgcta atcattcaaa ctacttaacc
      601 tgtgacagag ccaacacgca gtctgtcact gtcaggaaag tggtaaaact gcaactcaat
      661 tactgcaatg ccctcgtaat taagtgaatt tacaatatcg tcctgttcgg agggaagaac
      721 gcgggatgtt cattcttcat cacttttaat tgatgtatat gctatctttt ctgacgttag
      781 cctccgacgg caggcttcaa tgacccaggc tgagaaattc ccggaccctt tttgatcaag
      841 agcgatgtta atttgttcaa tcatttggtt aggaaagcgg atgttgcggg ttgttgttct
      901 gcgggttctg ttcttcgttg acatgaggtt gccccgtatt cagtgtcgct gatttgtatt
      961 gtctgaagtt gtttttacgt taagttgatg cggatcaatt aatacgatac ctgcgtcata
     1021 attgattatt tgacgtggtt tgatggcgta gatgcacgtt gtgacatgta gatgataatt
     1081 attatcattt tgcgggtcct ttccggcgat ccgacaggtt acggggcggc gacctcgcgg
     1141 gttttcgcta tttatgaaaa ttttccggtt taaggcgttt ccgttcttct tcgtcgtaac
     1201 ttaatgtttt tatttaaaat accccctgaa aagaaaggaa acgacaggtg ctgaaaacga
     1261 acttttgggc ctttgtcgtt tcctttctct gtttttggcc gtggaatgaa caatggaagt
     1321 caacaaaaag cagctggctg acattttcgg tgcgagtatc cgtaccattc agaactggca
     1381 ggaacaggga atgcccgttc tgcgaggcgg tggcaagggt aatgaggtgc tttatgactc
     1441 tgccgccgtc ataaaatggt atgccgaaag ggatgctgaa attgagaacg aaaagctgcg
     1501 ccgggaggtt gaagaactgc ggcaggccag cgaggcagat ctccagccag gaactattga
     1561 gtacgaacgc catcgactta cgcgtgcgca ggccgacgca caggaactga agaatgccag
     1621 agactccgct gaagtggtgg aaaccgcatt ctgtactttc gtgttgtcgc ggatcgcagg
     1681 tgaaattgcc agtattctcg acgggctccc cctgtcggtg cagcggcgtt ttccggaact
     1741 ggaaaaccga catgttgatt tcctgaaacg ggatatcatc aaagccatga acaaagcagc
     1801 cgcgctggat gaactgatac cggggttgct gagtgaatat atcgaacagt caggttaaca
     1861 ggctgcggca ttttgtccgc gccgggcttc gctcactgtt caggccggag ccacagaccg
     1921 ccgttgaatg ggcggatgct aattactatc tcccgaaaga atccgcatac caggaagggc
     1981 gctgggaaac actgcccttt cagcgggcca tcatgaatgc gatgggcagc gactacatcc
     2041 gtgaggtgaa tgtggtgaag tctgcccgtg tcggttattc caaaatgctg ctgggtgttt
     2101 atgcctactt tatagagcat aagcagcgca acacccttat ctggttgccg acggatggtg
     2161 atgccgagaa ctttatgaaa acccacgttg agccgactat tcgtgatatt ccgtcgctgc
     2221 tggcgctggc cccgtggtat ggcaaaaagc accgggataa cacgctcacc atgaagcgtt
     2281 tcactaatgg gcgtggcttc tggtgcctgg gcggtaaagc ggcaaaaaac taccgtgaaa
     2341 agtcggtgga tgtggcgggt tatgatgaac ttgctgcttt tgatgatgat attgaacagg
     2401 aaggctctcc gacgttcctg ggtgacaagc gtattgaagg ctcggtctgg ccaaagtcca
     2461 tccgtggctc cacgccaaaa gtgagaggca cctgtcagat tgagcgtgca gccagtgaat
     2521 ccccgcattt tatgcgtttt catgttgcct gcccgcattg cggggaggag cagtatctta
     2581 aatttggcga caaagagacg ccgtttggcc tcaaatggac gccggatgac ccctccagcg
     2641 tgttttatct ctgcgagcat aatgcctgcg tcatccgcca gcaggagctg gactttactg
     2701 atgcccgtta tatctgcgaa aagaccggga tctggacccg tgatggcatt ctctggtttt
     2761 cgtcatccgg tgaagagatt gagccacctg acagtgtgac ctttcacatc tggacagcgt
     2821 acagcccgtt caccacctgg gtgcagattg tcaaagactg gatgaaaacg aaaggggata
     2881 cgggaaaacg taaaaccttc gtaaacacca cgctcggtga gacgtgggag gcgaaaattg
     2941 gcgaacgtcc ggatgctgaa gtgatggcag agcggaaaga gcattattca gcgcccgttc
     3001 ctgaccgtgt ggcttacctg accgccggta tcgactccca gctggaccgc tacgaaatgc
     3061 gcgtatgggg atgggggccg ggtgaggaaa gctggctgat tgaccggcag attattatgg
     3121 gccgccacga cgatgaacag acgctgctgc gtgtggatga ggccatcaat aaaacctata
     3181 cccgccggaa tggtgcagaa atgtcgatat cccgtatctg ctgggatact ggcgggattg
     3241 acccgaccat tgtgtatgaa cgctcgaaaa aacatgggct gttccgggtg atccccatta
     3301 aaggggcatc cgtctacgga aagccggtgg ccagcatgcc acgtaagcga aacaaaaacg
     3361 gggtttacct taccgaaatc ggtacggata ccgcgaaaga gcagatttat aaccgcttca
     3421 cactgacgcc ggaaggggat gaaccgcttc ccggtgccgt tcacttcccg aataacccgg
     3481 atatttttga tctgaccgaa gcgcagcagc tgacggctga agagcaggtc gaaaaatggg
     3541 tggatggcag gaaaaaaata ctgtgggaca gcaaaaagcg acgcaatgag gcactcgact
     3601 gcttcgttta tgcgctggcg gcgctgcgca tcagtatttc ccgctggcag ctggatctca
     3661 gtgcgctgct ggcgagtctg caggaagagg atggtgcagc aaccaacaag aaaacactgg
     3721 cagattacgc ccgtgcctta tccggagagg atgaatgacg cgacaggaag aacttgccgc
     3781 tgcccgtgcg gcactgcatg acctgatgac aggtaaacgg gtggcaacag tacagaaaga
     3841 cggacgaagg gtggagttta cggccacttc cgtgtctgac ctgaaaaaat atattgcaga
     3901 gctggaagtg cagaccggca tgacacagcg acgcagggga cctgcaggat tttatgtatg
     3961 aaaacgccca ccattcccac ccttctgggg ccggacggca tgacatcgct gcgcgaatat
     4021 gccggttatc acggcggtgg cagcggattt ggagggcagt tgcggtcgtg gaacccaccg
     4081 agtgaaagtg tggatgcagc cctgttgccc aactttaccc gtggcaatgc ccgcgcagac
     4141 gatctggtac gcaataacgg ctatgccgcc aacgccatcc agctgcatca ggatcatatc
     4201 gtcgggtctt ttttccggct cagtcatcgc ccaagctggc gctatctggg catcggggag
     4261 gaagaagccc gtgccttttc ccgcgaggtt gaagcggcat ggaaagagtt tgccgaggat
     4321 gactgctgct gcattgacgt tgagcgaaaa cgcacgttta ccatgatgat tcgggaaggt
     4381 gtggccatgc acgcctttaa cggtgaactg ttcgttcagg ccacctggga taccagttcg
     4441 tcgcggcttt tccggacaca gttccggatg gtcagcccga agcgcatcag caacccgaac
     4501 aataccggcg acagccggaa ctgccgtgcc ggtgtgcaga ttaatgacag cggtgcggcg
     4561 ctgggatatt acgtcagcga ggacgggtat cctggctgga tgccgcagaa atggacatgg
     4621 ataccccgtg agttacccgg cgggcgcgcc tcgttcattc acgtttttga acccgtggag
     4681 gacgggcaga ctcgcggtgc aaatgtgttt tacagcgtga tggagcagat gaagatgctc
     4741 gacacgctgc agaacacgca gctgcagagc gccattgtga aggcgatgta tgccgccacc
     4801 attgagagtg agctggatac gcagtcagcg atggatttta ttctgggcgc gaacagtcag
     4861 gagcagcggg aaaggctgac cggctggatt ggtgaaattg ccgcgtatta cgccgcagcg
     4921 ccggtccggc tgggaggcgc aaaagtaccg cacctgatgc cgggtgactc actgaacctg
     4981 cagacggctc aggatacgga taacggctac tccgtgtttg agcagtcact gctgcggtat
     5041 atcgctgccg ggctgggtgt ctcgtatgag cagctttccc ggaattacgc ccagatgagc
     5101 tactccacgg cacgggccag tgcgaacgag tcgtgggcgt actttatggg gcggcgaaaa
     5161 ttcgtcgcat cccgtcaggc gagccagatg tttctgtgct ggctggaaga ggccatcgtt
     5221 cgccgcgtgg tgacgttacc ttcaaaagcg cgcttcagtt ttcaggaagc ccgcagtgcc
     5281 tgggggaact gcgactggat aggctccggt cgtatggcca tcgatggtct gaaagaagtt
     5341 caggaagcgg tgatgctgat agaagccgga ctgagtacct acgagaaaga gtgcgcaaaa
     5401 cgcggtgacg actatcagga aatttttgtc cagcaggtcc gtgaaacgat ggagcgccgt
     5461 gcagccggtc ttaaaccgcc cgcctgggcg gctgcagcat ttgaatccgg gctgcgacaa
     5521 tcaacagagg aggagaagag tgacagcaga gctgcgtaat ctcccgcata ttgccagcat
     5581 ggcctttaat gagccgctga tgcttgaacc cgcctatgcg cgggttttct tttgtgcgct
     5641 tgcaggccag cttgggatca gccgcctgac ggatgcggtg tccggcgaca gcctgactgc
     5701 ccaggaggca ctcgcgacgc tggcattatc cggtgatgat gacggaccac gacaggcccg
     5761 cagttatcag gtcatgaacg gcatcgccgt gctgccggtg tccggcacgc tggtcagccg
     5821 gacgcgggcg ctgcagccgt actcggggat gaccggttac aacggcatta tcgcccgtct
     5881 gcaacaggct gccagcgatc cgatggtgga cggcattctg ctcgatatgg acacgcccgg
     5941 cgggatggtg gcgggggcat ttgactgcgc tgacatcatc gcccgtgtgc gtgacataaa
     6001 accggtatgg gcgcttgcca acgacatgaa ctgcagtgca ggtcagttgc ttgccagtgc
     6061 cgcctcccgg cgtctggtca cgcagaccgc ccggacaggc tccatcggcg tcatgatggc
     6121 tcacagtaat tacggtgctg cgctggagaa acagggtgtg gaaatcacgc tgatttacag
     6181 cggcagccat aaggtggatg gcaaccccta cagccatctt ccggatgacg tccgggagac
     6241 actgcagtcc cggatggacg caacccgccg gatgtttgcg cagaaggtgt cggcatatac
     6301 cggcctgtcc gtgcaggctg tgctggatac cgaggctgca gtgtacagcg gtcaggaggc
     6361 cattgatgcc ggactggctg atgaacttgt taacagcacc gatgcgatca ccgtcatgcg
     6421 tgatgcactg gatgcacgta aatcccgtct ctcaggaggg cgaatgacca aagagactca
     6481 atcaacaact gtttcagcca ctgcttcgca ggctgacgtt actgacgtgg tgccagcgac
     6541 ggagggcgag aacgccagcg cggcgcagcc ggacgtgaac gcgcagatca ccgcagcggt
     6601 tgcggcagaa aacagccgca ttatggggat cctcaactgt gaggaggctc acggacgcga
     6661 agaacaggca cgcgtgctgg cagaaacccc cggtatgacc gtgaaaacgg cccgccgcat
     6721 tctggccgca gcaccacaga gtgcacaggc gcgcagtgac actgcgctgg atcgtctgat
     6781 gcagggggca ccggcaccgc tggctgcagg taacccggca tctgatgccg ttaacgattt
     6841 gctgaacaca ccagtgtaag ggatgtttat gacgagcaaa gaaaccttta cccattacca
     6901 gccgcagggc aacagtgacc cggctcatac cgcaaccgcg cccggcggat tgagtgcgaa
     6961 agcgcctgca atgaccccgc tgatgctgga cacctccagc cgtaagctgg ttgcgtggga
     7021 tggcaccacc gacggtgctg ccgttggcat tcttgcggtt gctgctgacc agaccagcac
     7081 cacgctgacg ttctacaagt ccggcacgtt ccgttatgag gatgtgctct ggccggaggc
     7141 tgccagcgac gagacgaaaa aacggaccgc gtttgccgga acggcaatca gcatcgttta
     7201 actttaccct tcatcactaa aggccgcctg tgcggctttt tttacgggat ttttttatgt
     7261 cgatgtacac aaccgcccaa ctgctggcgg caaatgagca gaaatttaag tttgatccgc
     7321 tgtttctgcg tctctttttc cgtgagagct atcccttcac cacggagaaa gtctatctct
     7381 cacaaattcc gggactggta aacatggcgc tgtacgtttc gccgattgtt tccggtgagg
     7441 ttatccgttc ccgtggcggc tccacctctg aatttacgcc gggatatgtc aagccgaagc
     7501 atgaagtgaa tccgcagatg accctgcgtc gcctgccgga tgaagatccg cagaatctgg
     7561 cggacccggc ttaccgccgc cgtcgcatca tcatgcagaa catgcgtgac gaagagctgg
     7621 ccattgctca ggtcgaagag atgcaggcag tttctgccgt gcttaagggc aaatacacca
     7681 tgaccggtga agccttcgat ccggttgagg tggatatggg ccgcagtgag gagaataaca
     7741 tcacgcagtc cggcggcacg gagtggagca agcgtgacaa gtccacgtat gacccgaccg
     7801 acgatatcga agcctacgcg ctgaacgcca gcggtgtggt gaatatcatc gtgttcgatc
     7861 cgaaaggctg ggcgctgttc cgttccttca aagccgtcaa ggagaagctg gatacccgtc
     7921 gtggctctaa ttccgagctg gagacagcgg tgaaagacct aggtaaagcg gtgtcctata
     7981 aggggatgta tggcgatgtg gccatcgtcg tgtattccgg acagtacgtg gaaaacggcg
     8041 tcaaaaagaa cttcctgccg gacaacacga tggtgctggg gaacactcag gcacgcggtc
     8101 tgcgcaccta tggctgcatt caggatgcgg acgcacagcg cgaaggcatt aacgcctctg
     8161 cccgttaccc gaaaaactgg gtgaccaccg gcgatccggc gcgtgagttc accatgattc
     8221 agtcagcacc gctgatgctg ctggctgacc ctgatgagtt cgtgtccgta caactggcgt
     8281 aatcatggcc cttcggggcc attgtttctc tgtggaggag tccatgacga aagatgaact
     8341 gattgcccgt ctccgctcgc tgggtgaaca actgaaccgt gatgtcagcc tgacggggac
     8401 gaaagaagaa ctggcgctcc gtgtggcaga gctggaagag gagcttgatg acacggatga
     8461 aactgccggt caggacaccc ctctcagccg ggaaaatgtg ctgaccggac atgaaaatga
     8521 ggtgggatca gcgcagccgg ataccgtgat tctggatacg tctgaactgg tcacggtcgt
     8581 ggcactggtg aagctgcata ctgatgcact tcacgccacg cgggatgaac ctgtggcatt
     8641 tgtgctgccg ggaacggcgt ttcgtgtctc tgccggtgtg gcagccgaaa tgacagagcg
     8701 cggcctggcc agaatgcaat aacgggaggc gctgtggctg atttcgataa cctgttcgat
     8761 gctgccattg cccgcgccga tgaaacgata cgcgggtaca tgggaacgtc agccaccatt
     8821 acatccggtg agcagtcagg tgcggtgata cgtggtgttt ttgatgaccc tgaaaatatc
     8881 agctatgccg gacagggcgt gcgcgttgaa ggctccagcc cgtccctgtt tgtccggact
     8941 gatgaggtgc ggcagctgcg gcgtggagac acgctgacca tcggtgagga aaatttctgg
     9001 gtagatcggg tttcgccgga tgatggcgga agttgtcatc tctggcttgg acggggcgta
     9061 ccgcctgccg ttaaccgtcg ccgctgaaag ggggatgtat ggccataaaa ggtcttgagc
     9121 aggccgttga aaacctcagc cgtatcagca aaacggcggt gcctggtgcc gccgcaatgg
     9181 ccattaaccg cgttgcttca tccgcgatat cgcagtcggc gtcacaggtt gcccgtgaga
     9241 caaaggtacg ccggaaactg gtaaaggaaa gggccaggct gaaaagggcc acggtcaaaa
     9301 atccgcaggc cagaatcaaa gttaaccggg gggatttgcc cgtaatcaag ctgggtaatg
     9361 cgcgggttgt cctttcgcgc cgcaggcgtc gtaaaaaggg gcagcgttca tccctgaaag
     9421 gtggcggcag cgtgcttgtg gtgggtaacc gtcgtattcc cggcgcgttt attcagcaac
     9481 tgaaaaatgg ccggtggcat gtcatgcagc gtgtggccgg gaaaaaccgt taccccattg
     9541 atgtggtgaa aatcccgatg gcggtgccgc tgaccacggc gtttaaacaa aatattgagc
     9601 ggatacggcg tgaacgtctt ccgaaagagc tgggctatgc gctgcagcat caactgagga
     9661 tggtaataaa gcgatgaaac atactgaact ccgtgcagcc gtactggatg cactggagaa
     9721 gcatgacacc ggggcgacgt tttttgatgg tcgccccgct gtttttgatg aggcggattt
     9781 tccggcagtt gccgtttatc tcaccggcgc tgaatacacg ggcgaagagc tggacagcga
     9841 tacctggcag gcggagctgc atatcgaagt tttcctgcct gctcaggtgc cggattcaga
     9901 gctggatgcg tggatggagt cccggattta tccggtgatg agcgatatcc cggcactgtc
     9961 agatttgatc accagtatgg tggccagtgg ctatgactac cggcgcgacg atgatgcggg
    10021 cctgtggagt tcagccgatc tgacttatgt cattacctat gaaatgtgag gacgctatgc
    10081 ctgtaccaaa tcctacaatg ccggtgaaag gtgccgggac caccctgtgg gtttataagg
    10141 ggagcggtga cccttatgcg aatccgcttt cagacgttga ctggtcgcgt ctggcaaaag
    10201 ttaaagacct gacgcccggc gaactgaccg ctgagtccta tgacgacagc tatctcgatg
    10261 atgaagatgc agactggact gcgaccgggc aggggcagaa atctgccgga gataccagct
    10321 tcacgctggc gtggatgccc ggagagcagg ggcagcaggc gctgctggcg tggtttaatg
    10381 aaggcgatac ccgtgcctat aaaatccgct tcccgaacgg cacggtcgat gtgttccgtg
    10441 gctgggtcag cagtatcggt aaggcggtga cggcgaagga agtgatcacc cgcacggtga
    10501 aagtcaccaa tgtgggacgt ccgtcgatgg cagaagatcg cagcacggta acagcggcaa
    10561 ccggcatgac cgtgacgcct tccagcacct cggtggtgaa agggcagagc accacgctga
    10621 ccgtggcctt ccagccggag ggcgtaaccg acaagagctt tcgtgcggtg tctgcggata
    10681 aaacaaaagc caccgtgtcg gtcagtggta tgaccatcac cgtgaacggc gttgctgcag
    10741 gcaaggtcaa cattccggtt gtatccggta atggtgagtt tgctgcggtt gcagaaatta
    10801 ccgtcaccgc cagttaatcc ggagagtcag cgatgttcct gaaaaccgaa tcatttgaac
    10861 ataacggtgt gaccgtcacg ctttctgaac tgtcagccct gcagcgcatt gagcatctcg
    10921 ccctgatgaa acggcaggca gaacaggcgg agtcagacag caaccggaag tttactgtgg
    10981 aagacgccat cagaaccggc gcgtttctgg tggcgatgtc cctgtggcat aaccatccgc
    11041 agaagacgca gatgccgtcc atgaatgaag ccgttaaaca gattgagcag gaagtgctta
    11101 ccacctggcc cacggaggca atttctcatg ctgaaaacgt ggtgtaccgg ctgtctggta
    11161 tgtatgagtt tgtggtgaat aatgcccctg aacagacaga ggacgccggg cccgcagagc
    11221 ctgtttctgc gggaaagtgt tcgacggtga gctgagtttt gccctgaaac tggcgcgtga
    11281 gatggggcga cccgactggc gtgccatgct tgccgggatg tcatccacgg agtatgccga
    11341 ctggcaccgc ttttacagta cccattattt tcatgatgtt ctgctggata tgcacttttc
    11401 cgggctgacg tacaccgtgc tcagcctgtt tttcagcgat ccggatatgc atccgctgga
    11461 tttcagtctg ctgaaccggc gcgaggctga cgaagagcct gaagatgatg tgctgatgca
    11521 gaaagcggca gggcttgccg gaggtgtccg ctttggcccg gacgggaatg aagttatccc
    11581 cgcttccccg gatgtggcgg acatgacgga ggatgacgta atgctgatga cagtatcaga
    11641 agggatcgca ggaggagtcc ggtatggctg aaccggtagg cgatctggtc gttgatttga
    11701 gtctggatgc ggccagattt gacgagcaga tggccagagt caggcgtcat ttttccggta
    11761 cggaaagtga tgcgaaaaaa acagcggcag tcgttgaaca gtcgctgagc cgacaggcgc
    11821 tggctgcaca gaaagcgggg atttccgtcg ggcagtataa agccgccatg cgtatgctgc
    11881 ctgcacagtt caccgacgtg gccacgcagc ttgcaggcgg gcaaagtccg tggctgatcc
    11941 tgctgcaaca ggggggccac ctcgctggcg gtggcgaccg gtgcgctggc gtatgcctgg
    12001 tatcagggca actcaaccct gtccgatttc aacaaaacgc tggtcctttc cggcaatcag
    12061 gcgggactga cggcagatcg tatgctggtc ctgtccagag ccgggcaggc ggcagggctg
    12121 acgtttaacc agaccagcga gtcactcagc gcactggtta aggcgggggt aagcggtgag
    12181 gctcagattg cgtccatcag ccagagtgtg gcgcgtttct cctctgcatc cggcgtggag
    12241 gtggacaagg tcgctgaagc cttcgggaag ctgaccacag acccgacgtc ggggctgacg
    12301 gcgatggcac gccagttcca taacgtgacg acggagcaga ttgcgtatgt tgctcagttg
    12361 cagcgttccg gcgatgaagc cggggcattg caggcggcga acgaggccgc aacgaaaggg
    12421 tttgatgacc agacccgccg cctgaaagag aacatgggca cgctggagac ctgggcagac
    12481 aggactgcgc gggcattcaa atccatgtgg gatgcggtgc tggatatcgg tcgtcctgat
    12541 accgcgcagg agatgctgat taaggcagag gctgcgttta agaaagcaga cgacatctgg
    12601 aatctgcgca aggatgatta ttttgttaac gatgaagcgc gggcgcgtta ctgggatgat
    12661 cgtgaaaagg cccgtcttgc gcttgaagcc gcccgaaaga aggctgagca gcagactcaa
    12721 caggacaaaa atgcgcagca gcagagcgat accgaagcgt cacggctgaa atataccgaa
    12781 gaggcgcaga aggcttacga acggctgcag acgccgctgg agaaatatac cgcccgtcag
    12841 gaagaactga acaaggcact gaaagacggg aaaatcctgc aggcggatta caacacgctg
    12901 atggcggcgg cgaaaaagga ttatgaagcg acgctgaaaa agccgaaaca gtccggcgtg
    12961 aaggtgtctg cgggcgatcg tcaggaagac agtgctcatg ctgccctgct gacgcttcag
    13021 gcagaactcc ggacgctgga gaagcatgcc ggagcaaatg agaaaatcag ccagcagcgc
    13081 cgggatttgt ggaaggcgga gagtcagttc gcggtactgg aggaggcggc gcaacgtcgc
    13141 cagctgtctg cacaggagaa atccctgctg gcgcataaag atgagacgct ggagtacaaa
    13201 cgccagctgg ctgcacttgg cgacaaggtt acgtatcagg agcgcctgaa cgcgctggcg
    13261 cagcaggcgg ataaattcgc acagcagcaa cgggcaaaac gggccgccat tgatgcgaaa
    13321 agccgggggc tgactgaccg gcaggcagaa cgggaagcca cggaacagcg cctgaaggaa
    13381 cagtatggcg ataatccgct ggcgctgaat aacgtcatgt cagagcagaa aaagacctgg
    13441 gcggctgaag accagcttcg cgggaactgg atggcaggcc tgaagtccgg ctggagtgag
    13501 tgggaagaga gcgccacgga cagtatgtcg caggtaaaaa gtgcagccac gcagaccttt
    13561 gatggtattg cacagaatat ggcggcgatg ctgaccggca gtgagcagaa ctggcgcagc
    13621 ttcacccgtt ccgtgctgtc catgatgaca gaaattctgc ttaagcaggc aatggtggga
    13681 ttgtcgggag tatcggcagc gccattggcg gggctgttgg tggcggcgca tccgcgtcag
    13741 gcggtacagc cattcaggcc gctgcggcga aattccattt tgcaaccgga ggatttacgg
    13801 gaaccggcgg caaatatgag ccagcgggga ttgttcaccg tggtgagttt gtcttcacga
    13861 aggaggcaac cagccggatt ggcgtgggga atctttaccg gctgatgcgc ggctatgcca
    13921 ccggcggtta tgtcggtaca ccgggcagca tggcagacag ccggtcgcag gcgtccggga
    13981 cgtttgagca gaataaccat gtggtgatta acaacgacgg cacgaacggg cagataggtc
    14041 cggctgctct gaaggcggtg tatgacatgg cccgcaaggg tgcccgtgat gaaattcaga
    14101 cacagatgcg tgatggtggc ctgttctccg gaggtggacg atgaagacct tccgctggaa
    14161 agtgaaaccc ggtatggatg tggcttcggt cccttctgta agaaaggtgc gctttggtga
    14221 tggctattct cagcgagcgc ctgccgggct gaatgccaac ctgaaaacgt acagcgtgac
    14281 gctttctgtc ccccgtgagg aggccacggt actggagt
//
LOCUS       DAZUDJ010000098        13774 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.098, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000098 DAZUDJ010000000
VERSION     DAZUDJ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13774
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.098"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            60..970
                     /gene="hlyE"
                     /locus_tag="ACHY1N_004349"
                     /pseudo
     CDS             60..970
                     /gene="hlyE"
                     /locus_tag="ACHY1N_004349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415700.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin HlyE"
     gene            complement(1177..1623)
                     /gene="ycgN"
                     /locus_tag="ACHY1N_004350"
     CDS             complement(1177..1623)
                     /gene="ycgN"
                     /locus_tag="ACHY1N_004350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309703.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HFS4046548.1"
                     /translation="MSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIY
                     FTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLAEGKDL
                     PAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ"
     gene            complement(1715..2374)
                     /gene="ycgM"
                     /locus_tag="ACHY1N_004351"
     CDS             complement(1715..2374)
                     /gene="ycgM"
                     /locus_tag="ACHY1N_004351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HFS4046549.1"
                     /translation="MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSAVPEEPVLF
                     IKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDL
                     TLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPAAEFTGDPQNTTLGLSVNGEQRQQG
                     TTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRV
                     L"
     gene            complement(2446..2739)
                     /locus_tag="ACHY1N_004352"
     CDS             complement(2446..2739)
                     /locus_tag="ACHY1N_004352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgL domain-containing protein"
                     /protein_id="HFS4046550.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMIL
                     PLDGRKKLVNADIEKVKLALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK"
     gene            2981..3382
                     /gene="pliG"
                     /locus_tag="ACHY1N_004353"
     CDS             2981..3382
                     /gene="pliG"
                     /locus_tag="ACHY1N_004353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="g-type lysoyme inhibitor PliG"
                     /protein_id="HFS4046551.1"
                     /translation="MKIKSISKAVLLLALLTSTSFAAGKNVNVEFSKGHSSAQYSGEI
                     KGYDYDTYTFYAKKGQKVHVSISNEGADTYLFGPGIDDSVDLSRYSPELDSHGQYSLP
                     ASGKYELRVLQTRNDARKNKTKKYNVDIQIK"
     gene            complement(3502..3870)
                     /gene="ycgJ"
                     /locus_tag="ACHY1N_004354"
     CDS             complement(3502..3870)
                     /gene="ycgJ"
                     /locus_tag="ACHY1N_004354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgJ family protein"
                     /protein_id="HFS4046552.1"
                     /translation="MNMMRIFYIGLSGVGMMFSSMASGHDAGGLQSPACGVVCDPYIC
                     VNSDGISPELTRKYLGEKAAENLQSLQGYDPSEFTFANGVFCDVKEKLCRDDRYFGVD
                     GKRSGKINQITTKMLFMCRE"
     gene            4390..5085
                     /gene="minC"
                     /locus_tag="ACHY1N_004355"
     CDS             4390..5085
                     /gene="minC"
                     /locus_tag="ACHY1N_004355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004857 - enzyme inhibitor activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA];
                     GO_process: GO:1901891 - regulation of cell septum
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HFS4046553.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLK
                     HAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGK
                     EKAPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIAD
                     GNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARL
                     QLVENALTVQPLN"
     gene            5109..5921
                     /gene="minD"
                     /locus_tag="ACHY1N_004356"
     CDS             5109..5921
                     /gene="minD"
                     /locus_tag="ACHY1N_004356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HFS4046554.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGV
                     AKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            5925..6191
                     /gene="minE"
                     /locus_tag="ACHY1N_004357"
     CDS             5925..6191
                     /gene="minE"
                     /locus_tag="ACHY1N_004357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032955 - regulation of division septum
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HFS4046555.1"
                     /translation="MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK"
     gene            complement(6563..6907)
                     /locus_tag="ACHY1N_004358"
                     /pseudo
     CDS             complement(6563..6907)
                     /locus_tag="ACHY1N_004358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(6942..7061)
                     /locus_tag="ACHY1N_004359"
     CDS             complement(6942..7061)
                     /locus_tag="ACHY1N_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFS4046556.1"
                     /translation="MPLSYAGYHHFIMMSLVSGEHNTPALSLQDESPGLVPAG"
     gene            complement(7022..7207)
                     /gene="ymgJ"
                     /locus_tag="ACHY1N_004360"
     CDS             complement(7022..7207)
                     /gene="ymgJ"
                     /locus_tag="ACHY1N_004360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmgJ"
                     /protein_id="HFS4046557.1"
                     /translation="MSRRYSSATITLVILFCRRPHCRKISVRQYYLKRVIFYPTTLQR
                     TACKKCLFLMRDIIISS"
     gene            7308..7481
                     /gene="ymgI"
                     /locus_tag="ACHY1N_004361"
     CDS             7308..7481
                     /gene="ymgI"
                     /locus_tag="ACHY1N_004361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmgI"
                     /protein_id="HFS4046558.1"
                     /translation="MSYSSFKIILIHVKNIIPIITATLILNYLNNSERSLVKQILIED
                     EIIVCATYLIPDI"
     gene            7483..7827
                     /gene="ymgG"
                     /locus_tag="ACHY1N_004362"
     CDS             7483..7827
                     /gene="ymgG"
                     /locus_tag="ACHY1N_004362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415690.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YMGG-like glycine zipper-containing protein"
                     /protein_id="HFS4046559.1"
                     /translation="MKKKILTFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNG
                     VNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVI
                     GGTGGAILGKMK"
     gene            7831..8166
                     /gene="ymgD"
                     /locus_tag="ACHY1N_004363"
     CDS             7831..8166
                     /gene="ymgD"
                     /locus_tag="ACHY1N_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmgD family protein"
                     /protein_id="HFS4046560.1"
                     /translation="MMMKKFALLAGLFVFAPMTWAQDYNIKNGLPSETYITCAEANEM
                     AKTDSAQVAEIVAVMGNASVASRDLKIEQSPDLSAKVVEKLNQVCAKDPQMLLITAID
                     DTMRAIGKK"
     gene            complement(8223..10544)
                     /locus_tag="ACHY1N_004364"
     CDS             complement(8223..10544)
                     /locus_tag="ACHY1N_004364"
                     /inference="COORDINATES: protein motif:HMM:TIGR01414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HFS4046561.1"
                     /translation="MQGKNTIVITGDYSIGLLSQTSGNLNTDTIIRVNSDGSVTPSFS
                     DGDDTFIVTAGNHAVGVLACASPGSARACVSSLDEESTTDTGSNENNAIAKLDMAKGE
                     ITTHGTESYAAYANGTVVKAGDTLDYTNASVTLTDVDITTHGDNAHAIAARQGTVSFN
                     QGEIYTTGPDAATAKIYNGGTVTLKNTSAVAHQGSGIVLESSINGQEATVDILSGSSL
                     RSANEILYHKNETSNVTITDSEVSSAADVFINNIKGHLTVDATNSKITGSANISTDDN
                     THTYLSLSDNSTWDIKADSTVSNLTVDNSTVYISRADGRDVEPTRLTITENYVGNNGV
                     LHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEF
                     IKDSRIFAGAYEYSLTRGNTEATNKNWYLTNFQATSGGETNSGGSSAPTVAPTPVLRL
                     EAGSYVANLAAANTLFVMRLNDRAGEMRYIDPVTEQERSSRLWLRQIGGHNAWRDSNG
                     QLRTTSHRYVSQLGADLLTGGFTDSDSWRLGVMAGYARDYNSTHSSVSDYRSKGSVRG
                     YCAGLYATWFADDISKKGAYIDAWAQYSWFKNSVKGDELAYESYSAKGATVSLEAGYG
                     FALNKSFGLEAAKYTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNIQTRLGFRT
                     FIRTQEKNSGPHGDDFEPFVEMNWIHNSKDFAVSMNGVKVEQDGASNLGEIKLGVNGN
                     LNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF"
     gene            complement(10661..10870)
                     /locus_tag="ACHY1N_004365"
     CDS             complement(10661..10870)
                     /locus_tag="ACHY1N_004365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046562.1"
                     /translation="MKLKKLSGFSLGLIALAVGNAYAEQFIQHDEYKHAVAIKDGKVK
                     DIDNALVITTGNGSYGYPLQERVAS"
     gene            complement(11270..11488)
                     /gene="ymgF"
                     /locus_tag="ACHY1N_004366"
     CDS             complement(11270..11488)
                     /gene="ymgF"
                     /locus_tag="ACHY1N_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division-associated protein YmgF"
                     /protein_id="HFS4046563.1"
                     /translation="MNNSNNLDYFTLYIIFSIAFMLITLLVILIAKPSTGLGEVLVTI
                     NLLNALVWLAINLVNRLRERLVNHRDQQ"
     gene            complement(11620..13143)
                     /gene="pdeG"
                     /locus_tag="ACHY1N_004367"
     CDS             complement(11620..13143)
                     /gene="pdeG"
                     /locus_tag="ACHY1N_004367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415686.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HFS4046564.1"
                     /translation="MRNTLIPILVAICLFITGVAILNIQLWYSAKAEYLAGARYAANN
                     INHILEEASQATQTAVNIAGKECNLEEQYQLGTEAALKPHLRTIIILKQGIVWCTSLP
                     GNRVLLSRIPVFPDSNLLLAPAIDTVNRLPILLYQNQFADTRILVTISDQHIRGALNV
                     PLKGVRYVLRVADDIIGPTGDVMTLNGHYPYTEKVHSTKYHFTIIFNPPPLFSFYRLI
                     DKGFGILIFILLIACAAAFLLDRYFNKSATPEEILRRAINNGEIVPFYQPVVNGREGT
                     LRGVEVLARWKQPHGGYISPAAFIPLAEKSGLIVPLTQSLMNQVARQMNAIASKLPEG
                     FHIGINFSASHIISPTFVDECLNFRDSFTRRDLNLVLEVTEREPLNVDESLVQRLNIL
                     HENGFVIALDDFGTGYSGLSYLHDLHIDYIKIDHSFVGRVNADPESTRILDCVLDLAR
                     KLSISIVAEGVETKEQLDYLNQNNITFQQGYYFYKPVTYIDLVKIILSKPKVKVVVE"
     gene            complement(13475..13723)
                     /gene="ymgC"
                     /locus_tag="ACHY1N_004368"
     CDS             complement(13475..13723)
                     /gene="ymgC"
                     /locus_tag="ACHY1N_004368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmgC"
                     /protein_id="HFS4046565.1"
                     /translation="MNNSIPERFIFQCALFKNLEREVFMTHGYVDSHIIDQALRLRLK
                     DETSVILSDLYLQILQYIEMHKTTLTDIIINDRESVLS"
BASE COUNT         3938 a         3189 c         2969 g         3678 t
ORIGIN      
        1 ttaatagttg taaaacagga gtttcattac aatttatata tttaaagagg cgaatgatta
       61 tgactgaaat cgttgcagat aaaacggtag aagtagttaa aaacgcaatc gaaactgcag
      121 atggagcatt agatctttat aataaatatc tcgatcaggt catcccctgg cagacctttg
      181 atgaaaccat aaaagagtta agtcgcttta aacaggagta ttcacaggca gcctccgttt
      241 tagtcggcga tattaaaacc ttacttatgg atagccagga taagtatttt gaagcaaccc
      301 aaacagtgta tgaatggtgt ggtgttgcga cgcaattgct cgcagcgtat atttttctat
      361 ttgatgagta caatgagaag aaagcatccg cccagaaaga cattctcatt aaggtactgg
      421 atgacggcat cacgaagctg aatgaagcgc aaaaatccct gctggtaagc tcacaaagtt
      481 tcaacaacgc ttccgggaaa ctgctggcgt tagatagcca gttaaccaat gatttttcag
      541 aaaaaagcag cttttccagt cacaggtaga taaaatcagg aaggaagcgt atgccggtgc
      601 cgcagccggt gtcgtcgccg gtccatttgg attaatcatt tcctattcta ttgctgcggg
      661 cgtagttgaa gggaaactga ttccagaatt gaagaacaag ttaaaatctg tgcagaattt
      721 ctttaccacc ctgtctaaca cggttaaaca agcgaataaa gatatcgatg ccgccaaatt
      781 gaaattaacc accgaaatag ccgccatcgg ggagataaaa acggaaactg aaacaaccag
      841 attctatgtt gattatgatg atttaatgct ttctttgcta aaagaagcgg caaaaaaaat
      901 gattaacacc tgtaatgagt atcagaaaag acacggtaaa aagacactct ttgaggtacc
      961 tgaagtctga taagcgatta ttctctccat gtactcaagg tataaggttt atcacattta
     1021 aaaacacaga cgttttttaa agattgagag ttacctgttg ataataaggt atcgggtaac
     1081 tctcattatg acagagcgct ttcaaaaaca gggctacgaa atggcgagca tccagacgta
     1141 tattaagaaa gcccccatca acatctatta aatttatcac tgcgcccagt caggtttatt
     1201 taagatatga tcctgccagt caatcacttc tgattctttc actgcgatat gacgcacaga
     1261 gatacgttca ccatgcattg ccgctttcga accagtaagt agcggatgcc acgcaggtaa
     1321 atctttacct tccgccagca aacgataagc gcaggtcatt ggcagccatt cgaatgttgg
     1381 cagattttca cgggttaatt taatgcagtc gggttcaaac tcgaaacgac gttcgtagtt
     1441 ccgacattga caagttttaa tattgagctg gcgacaggcg acgttagtga agtagatttc
     1501 gtcggtgtct tcatccatca gtttatgcag gcaacactga ccgcaaccat cacacaacga
     1561 ctcccattcc gcatcgctca tttcgtccag ggttttactt tgccagaaag gtacatcgct
     1621 catcaggtgt tccgccatta cgttaaaacg caccttataa ccagtctggc acagcgatgc
     1681 aagttttgcc gccgctttca ggcggcaaaa agtattacaa aacgcgagtt gtcaaagaat
     1741 gcccatcgaa agtgactgtc agctcatcac cgctttgcaa cgggccgacg ccatcaggcg
     1801 tgcctgtcaa cacaacgtca ccggccttga gggtaaaaaa cttgctcata taagcgatca
     1861 acggaacgat tttatggatc atgtccgcag tcgtaccttg ctggcgttgt tcgccgttta
     1921 cgctcaggcc cagcgttgta ttttgtggat cgccggtaaa ttccgccgcg gggataaacc
     1981 cggaaagcgg acaagagtta tcaaacgctt tagccttttc ccacggctgc ccggctttct
     2041 tcatttttcc ctgaacatca cgcaatgtca gatcaagcgc cacgccgtaa ccggcaatgg
     2101 ctttgcggac atgctcttcc gttgcctgac gcagcgtcgc gccaatcaac accgccagtt
     2161 cgacttcatg atgaactgaa ccgaaatcgg atgggatcgc caatggctgc cgcagatcgc
     2221 acagtgccgt ttctggttta ataaacagca ctggctcttc gggcactgcg ctgcccatct
     2281 ctttaatatg tttggcatag ttactgccaa cacagactac tttactcacc ggataatcca
     2341 gcagcgcacc ttgccagttg tgatgttgat acataacgtt cccctcacct tatcgtggat
     2401 atgaaaaccc gcgccgacaa agataatgcc accgccggat atcggttatt tgttagtgtc
     2461 gtctgttttc tgccccatga cggaaagatg ttgcttcagc aaatcttcgg gtggtggcgg
     2521 taactgcaaa tagtaacctt gctcggttaa tgccagttta accttttcaa tatcagcatt
     2581 gaccagtttc ttgcgcccat ccagcggcag aatcatcgct aactgaggct gaccaaaacc
     2641 tttcatcagt tcctcaggaa cacgcgaaaa atcgtctttt ttttcgacat ataaataggt
     2701 ctggtcacgc ttgctgcttc gataaatcac acaaaacata cttttactct ttaagatgcc
     2761 aggttttggc ataagctaac atcaatgaaa cccgcgccac aagccagcca gctgtagatt
     2821 tctgcggttt gttgagtcca tgccccttta taagtaatcc ccccggcaaa aaatgccgcg
     2881 ccgggatttt accgaacgca gaaaagccac tggaattctc ccgtaaggga ttgttatatt
     2941 ataacagttc atcgtactca ttctgaacag gagactacca atgaaaatca agagcatcag
     3001 taaggctgta ttgctgcttg cactgctaac ctccacgagc tttgctgcgg gtaagaatgt
     3061 caatgttgag ttcagcaaag gccatagcag cgctcagtac tccggcgaaa taaagggata
     3121 cgattacgat acatatacct tctatgccaa aaaaggtcag aaagtgcatg tgagtatctc
     3181 taatgaaggc gctgatactt acctcttcgg gccaggaatc gatgattcag ttgatttatc
     3241 cagatattca ccagaactcg atagtcacgg acaatactca ctccctgctt ctggcaaata
     3301 tgagctgcga gtgctgcaaa cccgaaacga cgcccgtaaa aacaaaacta aaaaatataa
     3361 cgtcgatatt caaattaagt aaatgtcaac cgacggggac tctccccgtc ataaacgtta
     3421 acgccccact cctctctgtc gctcaagagg ttaatgacga atagcagaca atgccgaata
     3481 gaacataatg taaacaaggc atcactcacg acacataaat aacatctttg tggtgatttg
     3541 attgattttt ccactccgct taccatccac accaaaataa cgatcatcac gacataattt
     3601 ttctttaaca tcgcaaaata caccgttagc gaatgtaaat tcgctgggat cgtagccttg
     3661 taatgattgt aagttttcag cggctttttc gccgagatat ttccttgtta actctgggga
     3721 aatgccatct gagttcacac aaatatacgg gtcgcaaaca acgccgcacg ccggagattg
     3781 aagtccgcca gcgtcatgtc cagacgccat tgatgagaac atcatcccca cacctgacaa
     3841 tccgatataa aaaatacgca tcatattcat agcacatcct gataatccaa ccgtacaaca
     3901 cttatgctca tttcatcatc aatccgtaat caaaaccgct gacctggacg agttacgatg
     3961 acctgacaga agtatcagac gtcttctgcg gtttctatga tagagcaatt ctgtggcgga
     4021 tattaagata acgggtatct gttctttaat gatgccgcaa aaaatggaaa gttaagaaag
     4081 cctggcgtgg tgaaaaaata cacttgcctc aatactggat atttaaacag gtctggagat
     4141 gctgtcacga ttagggtgcg gaaaaaggaa gcgtaaataa gaacaatcaa aagtacgacg
     4201 gcaatgggtt gattgacaag ggtatttttt aagctatgaa tcagcgccat ttatcacaga
     4261 atagactttt actctgaata aatgggaggg tgacttgcct caatataatc cagactataa
     4321 catgccttat agtcttcgga acatcatcgc gcgctggcga tgattaatag ctaattgagt
     4381 aaggccagga tgtcaaacac gccaatcgag cttaaaggca gtagcttcac tttatctgtg
     4441 gttcatctgc atgaggcaga acctaaggtt atccatcagg cgctggaaga caaaatcgct
     4501 caggcccccg catttttaaa acatgccccc gttgtactca acgtcagtgc actggaagac
     4561 ccggtaaact ggtcagcgat gcataaggcg gtttcggcaa ccggtttgcg ggttattggc
     4621 gtaagtggct gcaaagatgc gcaacttaaa gccgaaattg aaaagatggg gctgcctatc
     4681 ctgacggaag gaaaggaaaa agcgccgcgt ccagctcccg caccacaggc tccagcgcaa
     4741 aatacaacgc cggtcacaaa aacgcgttta atagataccc cggtgcgttc cggtcagcgt
     4801 atttatgctc cacaatgtga tctgattgtt acaagccacg ttagcgctgg ggccgaattg
     4861 attgccgatg ggaacattca tgtctatggc atgatgcgcg gtcgtgcgct tgcaggggca
     4921 agtggtgacc gggaaacgca aatattttgt acgaacctga tggcggaact ggtgtccatc
     4981 gcaggtgaat actggctgag tgatcaaatc ccagcagaat tttatggcaa agcggcgcga
     5041 ctgcagttag tcgaaaacgc tttgaccgtt caaccgttaa attgatccct ttttaacaag
     5101 gaatttctat ggcacgcatt attgttgtta cttcgggcaa agggggtgtt ggtaagacaa
     5161 cctccagcgc ggccatcgcc actggtttgg cccagaaggg aaagaaaact gtcgtgatag
     5221 attttgatat cggcctgcgt aatctcgacc tgattatggg ttgtgaacgc cgggtcgttt
     5281 acgatttcgt caacgtcatt cagggcgatg caacgctaaa tcaggcgtta attaaagata
     5341 agcgtactga aaatctctat attcttccgg catcgcaaac acgcgataaa gatgccctca
     5401 cccgtgaagg ggtcgccaaa gttcttgatg atctgaaagc gatggatttt gaatttatcg
     5461 tttgtgactc cccggcaggg attgaaaccg gtgcgttaat ggcactctat tttgcagacg
     5521 aagccattat taccaccaac ccggaagtct cctcagtacg cgactctgac cgtattttag
     5581 gcattctggc gtcgaaatca cgccgcgcag aaaatggcga agagcctatt aaagagcacc
     5641 tgctgttaac gcgctataac ccaggccgcg taagcagagg tgacatgctg agcatggaag
     5701 atgtgctgga gatcctgcgc atcaaactcg tcggcgtgat cccagaggat caatcagtat
     5761 tgcgcgcctc taaccagggt gaaccggtca ttctcgacat taacgccgat gcgggtaaag
     5821 cctacgcaga taccgtagaa cgtctgttgg gagaagaacg tcctttccgc ttcattgaag
     5881 aagagaagaa aggcttcctc aaacgcttgt tcggaggata agttatggca ttactcgatt
     5941 tctttctctc gcggaagaaa aacacagcca acattgcaaa agaacggctg cagattattg
     6001 ttgctgaacg ccgtcgcagc gatgcagaac cgcattatct gccgcagttg cgtaaagata
     6061 ttcttgaggt catttgtaaa tacgtacaaa ttgatcctga gatggtaacc gtacagcttg
     6121 agcaaaaaga tggcgatatt tctattcttg agctgaacgt gaccttaccg gaagcagaag
     6181 agctgaaata agcccgctgt aaaaacgcat ttatcttcaa ggcagagtca tttctgcctt
     6241 gagtttttca tccctctcat ccacgttgtg gtaaagcggc gagtattctt gctgatactc
     6301 ctcattgcta tttccacctc cccctttaca ccttaaggct gttcccacgc acagaacaaa
     6361 atgtttatgc ctggttgagt aaataaccct gttgttagtg tggatatact gggagatgat
     6421 aaccccgcaa tttcattatt cattgttctc ccataggatg aggtttcccg ccgtaactgg
     6481 cgggcttttt ttgccccaga attttctctt tcaacatcct gtaaacgaaa actgcgccga
     6541 agcgcagttt aatcgttgat ggtcagaacg accagttcac accagccacc gcgttccacg
     6601 gggactccac accggcacca tggctatacc ccaccccgaa atgcccgctt aacgtactgc
     6661 tgaatgaggc tttaatacct gcctggtata ttccacgtct gcccgacaaa tcattgacaa
     6721 aattaccgtc actattcact ttcacccgat tatcatcgac aaattctttg cgcacagccg
     6781 ccttcaggca gggttcaatt tccataccgt tccccagacg catgttgtaa ctcagcgttg
     6841 cacccagttc acgatatata ctgcgggtat cgactgattt cgattccatg ccattggata
     6901 aatgatagta gcgtctaagt gacctaagct ctgctgcaac atcagcccgc aggcaccaga
     6961 ccaggggatt catcctgaag agacagcgca ggtgtattgt gttcaccgct caccaaagac
     7021 atcatgatga aatgatgata tcccgcataa gaaagaggca ttttttacac gcagtgcgct
     7081 gaagtgtagt tggataaaaa atcactcttt tcagataata ctgtcgtacg cttatctttc
     7141 gacaatgagg ccgtcggcaa aataaaatga ctaatgtaat cgttgctgat gaatatcttc
     7201 tgctcacata aaaatcacac aataatattg ataaatcaga ttatcttacc tttacaacat
     7261 tgcgttaaca gtcaatgaca cttcttgaat aaaaatattg tcaatcaatg agttattcct
     7321 catttaagat tattctcatt cacgtaaaaa acataattcc tatcatcaca gccacgctca
     7381 ttttgaatta tctgaataat agcgagcgtt ctttagttaa gcagatctta attgaagacg
     7441 aaattattgt gtgtgcaact tacttaatac cggacatcta agttgaagaa aaaaatactt
     7501 accttcgggc ttatctcagc attgttctgc tccacgccag cgatggcgga tatgaatcgc
     7561 accacgaaag gtgcattgct aggcgcaggc gttggtttac ttactggcaa tggtgttaat
     7621 ggcgtactga aaggtgcagc tgttggcgct ggtgttggtg cagtaacaga aaaaggccgc
     7681 gacggtaaaa atgcgcgtaa aggtgcaaaa gtaggtgccg ccgttggtgc tgtcactggc
     7741 gttctgaccg gcaatggcct cgaaggggcg attaaaggtg ccgtgattgg cggtacgggt
     7801 ggtgcaattc tgggtaaaat gaaataagga atgatgatga aaaaatttgc tttactggcg
     7861 ggcctgtttg ttttcgcacc aatgacctgg gcgcaggact acaatattaa aaacggtttg
     7921 ccgtcagaaa cctatattac ttgcgcagaa gccaacgaaa tggcaaaaac tgacagcgca
     7981 caggttgcag aaattgttgc ggtaatgggt aatgccagcg ttgccagccg tgatttaaaa
     8041 attgagcaat ctccggatct gagcgccaaa gtggtagaaa aactgaatca ggtttgcgct
     8101 aaagacccgc aaatgctgtt gatcacggca attgatgaca ccatgcgtgc tatcggcaaa
     8161 aaataatatt tcatatgtac cgcgtcgatg aatacgacgc ggttttttag ctaacggcgg
     8221 gatcagaact tatatttcag gcccaccatc actgcggtgt cattgtagcc attatcaccc
     8281 agctgcacgc ccacattccc ccagacgctg gccgctggat tcaggttgcc atttacgcca
     8341 agtttaattt cccccaaatt actcgcccca tcttgttcga ctttcacacc gttcattgag
     8401 acagcaaaat ctttactgtt atggatccag ttcatttcaa caaaaggttc aaagtcgtca
     8461 ccgtgcggac cgctgttttt ctcctgagta cgaataaagg tgcggaaacc aagtcgggtc
     8521 tggatgttgt tatttgcgtc attctcaata cgtgagccat tggcttcggt gtgcgcatta
     8581 tgatcgacgc ccatccagat agcctgtgcc tgtggctgga atatccacgt gtatttcgcc
     8641 gcttccagac caaaggattt attcagggca aagccgtaac ccgcttccag cgagacggtt
     8701 gcgcctttcg cactatagga ttcataggct aattcatccc ctttcaccga gtttttaaac
     8761 cagctatatt gcgcccaggc gtcaatgtat gcgccttttt tactgatgtc atcggcaaac
     8821 caggtggcat acagccctgc gcaatagcct ctgacactcc ctttcgaacg ataatccgac
     8881 acgctggaat gagttgagtt gtagtcgcgg gcataaccag ccatcactcc caaacgccaa
     8941 ctgtcactgt cggtaaaacc accggttaac agatcggccc ctaactgcga gacgtagcga
     9001 tgcgaggtcg ttctcaactg tccgttgctg tcacgccagg cattatgccc gccaatttga
     9061 cgtagccaaa gtcggcttga acgctcctgt tcagttacag gatcgatgta gcgcatttca
     9121 cccgcacggt cgttcagacg cataacaaaa agagtgttag cggctgccag gttggcgacg
     9181 taacttccag cttcgaggcg caggacgggg gtaggcgcaa cagtaggcgc tgaacttcct
     9241 ccggagtttg tttcaccgcc gctcgttgcc tggaagttag tcagatacca gtttttattg
     9301 gtcgcttcgg tattacctcg ggttaatgaa tattcgtagg caccggcgaa aatcctcgaa
     9361 tccttaataa attccccatt tgattccccc tcaacgctga taatctctat cccatttaac
     9421 gtgtaagctc cgctgcctcc tgcattggta actttaactc gggttgttcc agaggtattt
     9481 ccattaataa cgactttatc cgtagctgaa ttatcatcac ccaattcagt tctgagatgc
     9541 aatacgccat tattaccaac gtaattttca gttattgtta atcttgttgg ttcgacatcc
     9601 cgtccatctg cccgggaaat atagaccgta ctattatcaa ccgtgaggtt gctcaccgtt
     9661 gagtcagctt taatatccca ggtactatta tctgaaagcg acagataggt atgagtgtta
     9721 tcatctgttg aaatattagc tgaacccgtt atttttgaat tagttgcatc gacggtcaaa
     9781 tgacctttaa tattattgat aaaaacatct gcagccgatg atacctcact atccgtaatg
     9841 gtcacgttac tcgtctcatt tttatggtag aggatttcat ttgctgaccg tagtgagcta
     9901 ccagataaaa tatctaccgt tgcttcctga ccatttatgg aagactccag cacaattcca
     9961 gacccctgat gcgcgactgc agatgtattt ttcagcgtca ccgtgccgcc attataaatt
    10021 ttagcagtcg cggcgtcagg acccgttgta taaatttctc cctggttaaa tgaaactgtc
    10081 ccctggcggg cagcgatggc atgagcattg tccccatgcg tggtgatatc aacatcggtt
    10141 aatgtaacgc tggcattggt ataatcaagc gtgtcaccag ccttgacgac agtgccatta
    10201 gcgtacgcgg cataactttc tgttccgtgg gttgtgatct ccccttttgc catatccagt
    10261 tttgctatgg cattattttc attacttcct gtatcggtag tactttcttc atcaagagaa
    10321 gatacacacg cacgcgcgct tccgggagat gcacacgcaa gaacgccgac tgcgtgatta
    10381 cccgcagtaa caataaatgt atcatctccg tcagaaaaag agggggtaac cgaaccgtca
    10441 gagttgactc ttattatggt gtcagtattc aggtttccac tcgtttgact tagcaaacca
    10501 attgagtaat cccccgttat gacaatcgtg tttttaccct gcaaaataac agcaccgcca
    10561 aattcactta cgattgcgct agctgttaat gctgtgctta gaggactatt gtcagaagga
    10621 tataaaccgc ccgttgttac aatgacgcca ttgttaatgg ttaacttgct accctctcct
    10681 gcaacggata cccgtaactt ccattacccg ttgttataac tagcgcatta tcaatatctt
    10741 ttacttttcc atcttttatt gccacagcat gtttatattc atcgtgctga ataaactgtt
    10801 cagcatatgc attacccacc gccagagcaa taagtcccaa actaaacccg gagagttttt
    10861 tcagtttcat agattaacca tccattcatt ggattaacaa acattcctgg tcaaataacc
    10921 tatgcgttca gattaccaaa acggagggta aagacaaaaa caaaagcaca aaaaatttaa
    10981 atagataaac agcgacaata tataaatgat aaataagtcg gcattatcat ttttcacctt
    11041 attttcatga cattgatcac tttagggtga cgattttgtt taacaaataa ctcttcgaca
    11101 tcaaaattgt taatagttgc gatgaggatt atttcggtga tatataaaaa caaccgtgat
    11161 aacaccaggg ttgacaacta tttgcgcaat aatgcctttc cttcaatgat ccaggcgttc
    11221 actgccagca acccattcag ccgcatactg acagtgagaa actgaaagat tattgctgat
    11281 ccctgtggtt gacgagtctt tctcttaatc gattaaccag attgatcgcc agccaaacaa
    11341 gggcattaag caaatttatc gtcacaagca cttctcccag cccggtactg ggttttgcaa
    11401 taaggatgac caggagggtg atcagcataa atgcaatgga aaagatgata tagagagtga
    11461 aataatccag attattacta ttgttcatgc tactaatggc aatcctgtca aaactttcaa
    11521 acaattatag caaacaaaat aatgaacaat agtaacaaga ggcaacgagc taattagctg
    11581 tctataatta caccgcacta tggccttact gatcaatttt cactcaacca caaccttcac
    11641 cttcggttta gaaaggataa ttttgaccag gtcgatgtat gtaacaggtt tatagaaata
    11701 ataaccctgc tgaaatgtga tattattttg gttcagatag tcaagttgtt ctttcgtttc
    11761 gacaccttca gcgacgatac tgatcgaaag tttacgcgcc agatccaata cacaatccag
    11821 aattcgggtt gattctgggt ctgcgtttac gcggccaacg aaactgtgat caattttgat
    11881 ataatcaata tgcaggtcat gaagataaga aagccctgag tagccagtac cgaaatcatc
    11941 cagcgcgatg acaaaaccat tttcatgcag aatgttcaac cgctgaacca gactttcatc
    12001 aacattcaat ggctcacgct cggtgacttc cagaacaagg tttaaatcgc ggcgggtaaa
    12061 actgtcacgg aaatttaaac actcgtcgac aaacgtcggc gaaataatat gcgaagcgct
    12121 aaaattaatt ccaatatgaa aaccttccgg caatttactc gcgatagcgt tcatctgtct
    12181 ggcaacctga ttcatcaggc tttgcgtaag cggaacgatt aatccggatt tttcagcaag
    12241 tggaataaat gccgcgggtg atatatatcc accgtgaggt tgtttccagc gggctaacac
    12301 ctcaactccc cgcaatgtcc cttcccgacc atttaccaca ggttggtaaa aagggacgat
    12361 ctccccatta tttattgccc gtcgcaggat ctcttcaggc gttgcgcttt tattgaaata
    12421 tctatcaagc aggaaggcag cggcgcaggc gattaacaga ataaatatta aaattccaaa
    12481 gcctttatcg ataagtctgt agaagctaaa gagtggcggc gggttaaaga taatagtgaa
    12541 atgatatttt gtggagtgaa ccttctcggt atagggataa tgtccattaa gcgtcatcac
    12601 atcacccgtt ggtccaataa tgtcatccgc cacgcgtaat acatacctta cccctttcaa
    12661 gggtacatta agcgccccgc gaatatgttg atcacttatc gtaaccaaaa tgcgcgtatc
    12721 tgcaaattgg ttctgataga gcaggatagg taatctatta acggtgtcga ttgctggagc
    12781 caacagtaaa ttactgtccg ggaaaacagg aatacgagac aacaggaccc gattcccagg
    12841 cagggatgta caccagacta ttccctgttt gagaatgatg attgtgcgca ggtgaggttt
    12901 cagagctgct tcagtgccaa gctgatattg ctcctcgagg ttgcattcct tcccggcaat
    12961 gttaaccgct gtttgagtcg cttgtgacgc ttcttcaagt atatgattga tattgttggc
    13021 ggcatatctc gctcccgcca ggtactctgc ttttgcggaa taccagagct ggatgttcaa
    13081 aatagcgaca ccggtaataa acaagcatat cgcaacgagg atgggtatga gtgtattgcg
    13141 catttgcttg tcccggccaa agggtttaat acatgaaaat gccattcatt cgctcgcgct
    13201 ggcatctaca gagagcatgg tagagagcat aagaaatatc cacgccgaag ataaaatttt
    13261 ctccatcttg atctaaccca ttaattattg agcataatgt aggcagtaca aaataagtta
    13321 ggcgggatat caggcgtcaa gaatggagag cgagaactct ccattcttga cacctgatat
    13381 tgcggacata ataagaaagc ataacgcctg aaatgctcac tttgcatcag catggtgata
    13441 cagctgatgt ttattctaaa accttactca agttctaaga gagcacggat tccctgtcat
    13501 taataatgat atccgttagt gtagtcttat gcatttcaat gtactgcaat atttgcagat
    13561 agagatcaga aagaatcaca ctggtttcat cttttaaacg caagcgtaaa gcctgatcaa
    13621 taatatgact atcaacatac ccatgcgtca tgaacacctc cctctcgaga tttttaaaca
    13681 aagcacattg aaaaataaat ctctctggga ttgaattatt catgtcagcc tcgtagaaat
    13741 attaacccaa taaaattatg ctgtgtatag tcta
//
LOCUS       DAZUDJ010000099        13414 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.099, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000099 DAZUDJ010000000
VERSION     DAZUDJ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13414
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.099"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..846
                     /locus_tag="ACHY1N_004369"
                     /pseudo
     CDS             1..846
                     /locus_tag="ACHY1N_004369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709843.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
     gene            complement(999..2648)
                     /locus_tag="ACHY1N_004370"
     CDS             complement(999..2648)
                     /locus_tag="ACHY1N_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006885 - regulation of pH [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HFS4046566.1"
                     /translation="MEIFFTILIMTLVVSLSGVVTRVMPFQIPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVVVTVVGIGF
                     LIYWVVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMIFTVGGATVEFMKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILETSLMAAEIDPNVEIWMLFTDIILIYAALMLVRFGW
                     LWTMKKFSNRFLKKKPMEFGSWTTREILIASFAGVRGAITLAGVLSIPLLLPDGNVFP
                     ARYELVFLAAGVILFSLFVGVVMLPILLQHIEVADHSQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSVQEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLLEALLIEENQ"
     gene            complement(2799..4148)
                     /gene="ghxP"
                     /locus_tag="ACHY1N_004371"
                     /gene_synonym="yjcD"
     CDS             complement(2799..4148)
                     /gene="ghxP"
                     /locus_tag="ACHY1N_004371"
                     /gene_synonym="yjcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxP"
                     /protein_id="HFS4046567.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGL
                     IFDPNVHFSGVFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI"
     gene            complement(4694..5158)
                     /gene="soxR"
                     /locus_tag="ACHY1N_004372"
     CDS             complement(4694..5158)
                     /gene="soxR"
                     /locus_tag="ACHY1N_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HFS4046568.1"
                     /translation="MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIGEAFGVLPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN"
     gene            5244..5567
                     /gene="soxS"
                     /locus_tag="ACHY1N_004373"
     CDS             5244..5567
                     /gene="soxS"
                     /locus_tag="ACHY1N_004373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HFS4046569.1"
                     /translation="MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSD
                     YRHRL"
     gene            complement(5570..7156)
                     /gene="pdeC"
                     /locus_tag="ACHY1N_004374"
     CDS             complement(5570..7156)
                     /gene="pdeC"
                     /locus_tag="ACHY1N_004374"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdeC"
                     /protein_id="HFS4046570.1"
                     /translation="MSHRARHQLLALPGIIFLVLFPIILSLWIAFLWAKSEVNNQLRT
                     FAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDN
                     HFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
                     FWSEVMSDDPTLQWGVYDTVTKTFFSLSKEASAATFSPLIHLKDLTVQRNGYLYATVY
                     STKRPIAAIVATSYQRLITHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQ
                     RALEKHQLCLYYQPIIDIKTEKCIGAEALLRWLGEQGQIMNPAEFIPLAEKEGMIEQI
                     TDYVIDNVFRDLGAYLATHADRYVSINLSASDFHTSRLIARINQKTEQYAVRPQQIKF
                     EVTEHAFLDVEKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVE
                     TLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEEQVNWLRKRGVRYCQGWFFAKAMP
                     PQVFMQWMEQLPARELTRGQ"
     gene            7586..7867
                     /locus_tag="ACHY1N_004375"
     CDS             7586..7867
                     /locus_tag="ACHY1N_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcB family protein"
                     /protein_id="HFS4046571.1"
                     /translation="MATLTTGVVLLRWQLLSAVMMFLASTLNIRFRRSDYVGLAVISS
                     GLGVVSACWFAMGLLGITMADITAIWHNIESVMIEEMNQTPPQWPMILT"
     gene            complement(7966..8502)
                     /gene="ssb1"
                     /locus_tag="ACHY1N_004376"
     CDS             complement(7966..8502)
                     /gene="ssb1"
                     /locus_tag="ACHY1N_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HFS4046572.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK
                     ATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEV
                     VVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
                     PAAPSNEPPMDFDDDIPF"
     gene            8756..11578
                     /gene="uvrA"
                     /locus_tag="ACHY1N_004377"
     CDS             8756..11578
                     /gene="uvrA"
                     /locus_tag="ACHY1N_004377"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFS4046573.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLA
                     ESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEA
                     PWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAG
                     QRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVSGTPETVAECEASHTARFLKPML"
     gene            complement(11613..11969)
                     /locus_tag="ACHY1N_004378"
     CDS             complement(11613..11969)
                     /locus_tag="ACHY1N_004378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFS4046574.1"
                     /translation="MTISELLQYCMAKPGAEQSVHNDWKATQIKVEDVLFAMVKEVEN
                     RPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWSTVYLDGSLPDSQIYYLVDASYQQ
                     AVNLLPEEKRKLLVQL"
     gene            complement(11973..12389)
                     /locus_tag="ACHY1N_004379"
     CDS             complement(11973..12389)
                     /locus_tag="ACHY1N_004379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="HFS4046575.1"
                     /translation="MWYQKTLTLSAKSRGFHLVTDEILNQLADMPRVNIGLLHLLLQH
                     TSASLTLNENCDPTVRHDMERFFLRTVPDNGNYEHDYEGADDMPSHIKSSMLGTSLVL
                     PVHKGRIQTGTWQGIWLGEHRIHGGSRRIIATLQGE"
     gene            complement(12500..13213)
                     /gene="aphA"
                     /locus_tag="ACHY1N_004380"
     CDS             complement(12500..13213)
                     /gene="aphA"
                     /locus_tag="ACHY1N_004380"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0003993 - acid phosphatase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HFS4046576.1"
                     /translation="MRKITQAISAVCLLFALNSSAVALASSPSPLNPGTNVARLAEQA
                     PIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPGFWRGKKTFSPESEDYLKNPVFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPAT
                     NMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTY
                     KPLPQAGAFGEEVIVNSEY"
BASE COUNT         3502 a         3489 c         3250 g         3173 t
ORIGIN      
        1 ttcacacctt agcctgaaag gtatcgtgat taaagatgaa gatttatcca attcgaattt
       61 tgcaggttgc agactacaaa actctatttt ccaggactgt aatatgtata gaacgaattt
      121 tattgcgcca taatggaaaa aatacttttt gataattgta ttctcgatga ctcatatttc
      181 gctcatgtaa aaatgactga cgggactcta aatgcatgct ccgctatgca ttttcaattc
      241 tacaatgcag caatgaatag agccaatatt aaaaatacct tccttgacca ttcaaatttt
      301 tatatggcgt acatggctga ggtaaatctt tataaagtaa tagcgccata tgttaattta
      361 tttaaagccg accttagttt ctctaaactc gatttaatta actttgaaca tgctgatctg
      421 tctcgcgtca atctgaacaa agcaatcctc cagaatataa acttaattga tagcaaactc
      481 ttttgtacgt ggctgacaaa tacattcctc gaaatggtta tatgtaccgg ctctaatatg
      541 gctaaggttg attttaatga tgccaattta agcaactgcc atttcaactg ttctatttta
      601 acaaaagcct gtatgtttaa tacccgtctc tatcgggtta atttcgatga ggctagcgtc
      661 caaggaatgg gcatttccat tctccgtggg gaggaaaata tccccattga tagtgatacc
      721 ctggtaacac tacagaaatt ctttgaagaa gattgtacct ctcatactgg catgtcacaa
      781 actgaggata atattaatgc agccgctatg aagattactg cagatattat gcaacacgca
      841 gattgaggtt aagtcgaaga acagccaatg aattgacttt acaagaggat aacttatttg
      901 ttttagaatc atgaatgtta gcccgagcta acctgttaaa ggtgcaaaag attgcacctt
      961 tttcagatta cctcgggcct ggttacgtcg ctttcggctt actgattttc ctcaattagc
     1021 aacgcttcaa gcaaatcgag atcgtgcagt aatttttgca gcgtttcgtt gctgatctcc
     1081 cgcgtggcgc gcaggtggta cagttcagca cgttcagaac gcaatgccgc cagacggaag
     1141 cgacgctcaa ggttctcttc ctgcacggaa ctttcaacgt cgttacgtcc atcggcgcga
     1201 cgacgcaggt taccaatgac gcgagaactg acctccgtaa gcagctggtt atcgatattc
     1261 tcttcggtat ccgccgccag acgctcctcc attttctgga tcgccacaat cgccacttct
     1321 gccgttgccg ctcgcgcaat acgttcttct ttcaattgtt gcgaatggtc cgcgacttca
     1381 atgtgttgta gcagaatagg caacatcacc acgccgacaa acagcgagaa gagaatgacg
     1441 ccagccgcca ggaacaccag ctcatagcgc gccgggaaga cgttaccatc cggcaagagc
     1501 agcgggattg agagcacacc ggccagagtg atcgccccac gcaccccggc gaaagacgcg
     1561 atcaggattt ctcgtgtggt ccacgaacca aactccatcg gcttcttctt caggaagcgg
     1621 ttgctgaact ttttcatcgt ccacagccag ccgaaacgga ccagcatcag cgccgcatat
     1681 atcagaataa tatcggtaaa cagcatccag atttcgacgt tagggtcgat ttctgctgcc
     1741 atcagcgacg tctccagaat acccggcagc tgcagaccta acagcaggaa caccatgccg
     1801 ttaaagacaa attccagcat cgcccaggtg ctgtttgcac gcaggcgcat tgccagcggc
     1861 gcacggcgca tcacaccgga gcgggtgatg gtcatcccgg cggcaaccgc agcgaggatg
     1921 ccggaaacgc caatatgttc ggcaatcaga taagaagcga atggcagcaa gaacagcaga
     1981 acaatctgcg tcgcgggttc atcaccgccc cagcggctga ggaatcgcag cgagcgacca
     2041 tacagccagc tcaccacaaa accggcaaga ataccgccaa tggctacttt cataaattcg
     2101 accgtcgcac cgccgacggt gaagatcatc gtccccatcg ccactgccac ggcaaacttc
     2161 aacgacacca ggccggaagc gtcattcatc aacgcttcgc cctgcaaaat gcccatgatt
     2221 tttttcggga tgcgcccttc gccaacaatc ccggagagcg ccacagcatc ggtcggagaa
     2281 agtaccgccg ccagcgcaaa ggcggggatc agcggaatgc ccggcaccac ccagtaaata
     2341 aggaagccaa tgccgaccac ggtgaccacc accagcgcca gcgcgaggcc gaaaatctct
     2401 cgaccatgtt cgagaaattc acgggtcggc gttttccagc catcagcgaa cagcaacggc
     2461 gggataaaca agactaaaaa gagttcagga tcaaactcca catgcaaacc aaacgtcggc
     2521 cacgccagta gcgcaccgat ggcgatttgc ataagcggaa gcgggatctg aaagggcatg
     2581 acacgagtga ccaccccgga cagcgagacc acgagggtca ttatcagtat ggtgaagaag
     2641 atttccatgc gttccctgtt tgcgatgttt tttatgatct gagaaagacg ttatgcctga
     2701 attctcattt tttcagaata tcgcaaaagc tcacacaatg tgcggagaaa ataaaaacgg
     2761 gcagccattg ccacccgttt tcagaatccg atgaaagatt agatagccca gccacccgca
     2821 tagaaggtca ccagcgccac ggcgataacg accgtaccga tgttcaactt gcgccattcg
     2881 ccggaaacca gacgaccaat caccagagtc gcgaagccga tcatgatgcc tgttacgatg
     2941 ttacaggtca gcacgatgaa taccgccgta accagacccg ccatcgcatc aacaaaatca
     3001 gcaaagtcga ttttcgccac gttgctcagc atcagcaggc caacgtacat cagcgccgga
     3061 gccgttgcat accccggaac gaggtaagag agcggagaga ggaacagaat cagcaggaac
     3121 agcacgccaa cggtgatagc cgtcaaaccg gttttaccgc ccgccgccgt acccgccgca
     3181 gactcgatgt ataccgctgc cggagctgca cccaccaggc cagagaaaac gctgctcatg
     3241 gagtcagtgg tcagtgcttt cccaccgtcg ataatttgcc catctttatc cagcaggttc
     3301 gcctggccgg cgacggcacg gatagttccg gtggcatcaa atactgccgt cattaccagc
     3361 gccagaacgc ttggcaggac tacaggattc agcgcgccca taatgtccag gctgccaatc
     3421 agtgagttgc cgttttcatc gctcaatgaa ggcatggcga aaacgccgga gaaatggacg
     3481 ttaggatcga agatcaaacc gacaattgag ataccgataa tggtcagcag aatgccacca
     3541 gggactttca gtttttccag gccgatgatc accgccagac ctaccagtga cataatcacc
     3601 gggaaggtcg cgaaatcacc cagcgcaacg ggcagaccat caagcgggtt tttaatcacc
     3661 agaccgacac cgttagcggc aatgagcagc aggaacagac cgataccaat ccccgtgccg
     3721 tgcgccacac cgtgcggcaa gttgcgcaaa atccagctac ggatacccgt ggcagaaatt
     3781 accgtaaaca gcacacccat caggaacacg gcacccagcg cgacaggtac gctaatatgt
     3841 tgccccagca ccaggctgaa tgcggtaaac gccgtcaggg agatggcgca accaatcgcc
     3901 aacggcagat tagcccacag acccatcacg atagaaccga gtccggcaac cagacaggtt
     3961 gcaacgaaaa ctgccgcagg cgggaagcct gctttaccca acatacctgg aacgacgatg
     4021 accgagtaga ccatcgccag aaacgttgtt aacccggcaa ccacttcctg acggacagtg
     4081 cttccacgtt gtgaaatttt aaaccaggcg tcgagtgaac cgccggtacg cgctgatggc
     4141 gtagacataa gaaaacatcc cctgagagtt taattttcgt caagatgcgt ggcggacaat
     4201 cccctgccag cgaaacgtta tcttcctgct ccaggtttgc gacaatttac tgcgtcgcaa
     4261 aaaagcaaac gtttagctcc gcgcatacaa aacgggtggt aaaaaaagca aacgattatc
     4321 cggcgatcat agcggctttt tcaaccgaag tttgctgctt ttttctcttt tattgtcttg
     4381 acgatgaaaa accaggcaat tgatgcgcaa acgttatcgt cggtgcgcaa gattgcagcg
     4441 ttatcgagcc gtataccgtt caggattgcg ataaaaaatc gtctgagatg acaaaaatat
     4501 tgcggataaa aagtatactt ttacactggc gaagaaatgc cggtgacata caattaaagc
     4561 atcaacacca accggaacct ccaccacgtg ctcgaatggg gtgtgttgac gtcgggggaa
     4621 accctcctgt gtaccagcgg gatagagaga aagacaaaga ccggaaaaca aactaaagcg
     4681 cccttgtggc gctttagttt tgttcatctt ccagcaagcg tgcgccggta ccttcttctc
     4741 ctaagcggtc gcccgggtta cgcaacgggc aatcactgcg cgaaaggcag ccacaaccaa
     4801 tacatccgtc cagttcgtca cgcagcgcta ctaaggtatg aatgcgccga tccaactctt
     4861 ctcgccattg ggacgaaagc tgtttccact ctttcgcact taacgtatgc ccttcgggca
     4921 acacgccaaa cgcttcacca atggtcgcca gcggaatgcc aatacgctga gcaattttga
     4981 taattgcaac atatcgcaac acatcacgtt tatatcgccg ctgattgccg ctgttacgga
     5041 tactggtaat caacccttta ctttcataga aatgcagcgc cgataccgcc acaccgctgc
     5101 gtttcgccac ttcgccgggg gttagcagcg ctttaatgcg gggtaatttc ttttccataa
     5161 atcgctttac ctcaagttaa cttgaggaat tatactcccc aacagatgaa ttaacgaact
     5221 gaacactgaa aagaggcaga tttatgtccc atcagaaaat tattcaggat cttatcgcat
     5281 ggattgacga gcatattgac cagccgctta acattgatgt agtcgcaaaa aaatcaggct
     5341 attcaaagtg gtacttgcaa cgaatgttcc gcacggtgac gcatcagacg cttggcgatt
     5401 acattcgcca acgtcgcctg ttactggccg ccgttgagtt gcgcaccacc gagcgtccga
     5461 tttttgatat cgcaatggac ctgggttatg tctcgcagca gaccttctcc cgcgttttcc
     5521 gtcggcagtt tgatcgcact cccagcgatt atcgccaccg cctgtagttt tattgcccgc
     5581 gcgttaactc ccgcgcgggt aattgctcca tccattgcat aaacacctgc ggcggcatcg
     5641 ccttcgcaaa aaaccatccc tggcaatagc gcacgccgcg tttgcgcagc cagttaacct
     5701 gctcctcagt ttcgacgcct tcagcgatcg tttttaaccc caggctgtgc gccagctcga
     5761 tgatgtgttc cgcaatcaaa tgactggttt tgtgggtggt cagcgtttca acaaacgatt
     5821 tatcgatttt caaaatatcg acattcaatg atttaaggtt atgcaagtta gagtagccaa
     5881 taccaaaatc atcaattgcc acttcgtaac cagcctggcg gaaagccaga ataatcggcg
     5941 tcattttttc gacatcaaga aatgcatgct cagtcacttc aaatttaatt tgctgcggac
     6001 gcaccgcgta ttgctctgtt ttctgattga ttcgcgctat caaccgtgac gtatgaaaat
     6061 cggaggccga caggttaata gaaacatagc gatcggcatg tgttgccaag tacgcgccca
     6121 gatcgcggaa gacattatca ataacataat cagttatctg ttctatcatc ccctcctttt
     6181 ctgccagcgg aataaactct gccggattca ttatttgccc ctgctcacca agccaacgta
     6241 acaacgcttc agcgccgata catttttctg ttttgatatc gattattggc tggtaataaa
     6301 gacaaagttg atgtttttcg agggcgcgtt gcaatttacg tttgggagat aaatagtttt
     6361 gtcgaatacg tagccagagt aatagcagaa caagactccc caaaataccg gcgggcaacg
     6421 caaaaataag atgattataa aaatgggtta taagacgttg atatgaagtc gcaacaatgg
     6481 ctgcaattgg gcgttttgtc gaataaactg tcgcatataa atagccattt ctttgtacgg
     6541 ttaaatcctt caaatgaatc agcggagaaa acgttgctgc cgaggcctct ttgcttaacg
     6601 agaaaaaggt tttcgtcacc gtatcataca caccccattg caatgtcggg tcatcagaca
     6661 tcacttcact ccagaagaga gggttgataa ccgccacata atttccccgc tgcatatagg
     6721 tcattttata gccagagaaa aaaggcgtat cgcggtaata atagatagaa acgttaggtt
     6781 cacgcttata atcggccggt gcaatcgtat agccgtttac aggcgctatc agcgatgagc
     6841 ataaaaaatg gttatcacgg gcatagatca attcattaat ataaagatag ccacgaataa
     6901 tattcaacat tcgcttttga tgggctggag tgcaaacttg cccctgatag cgttcagctg
     6961 catcgctcac taaatctgcc tggcgaatga ccagctcgga tttatccagt gccagttgag
     7021 caaaggttcg gagctgatta ttcacttctg attttgccca aaggaaggca atccatagcg
     7081 aaagaatgat gggaaagaga actaaaaaga taatgcccgg caacgccagt aattggtgtc
     7141 gtgcacgatg actcattgct atcaatttcc tgcctgttta tacccggcca ttgcaaggtg
     7201 aaaaccctgg gtaccgacgt ctttagataa atcttacggt ataaatagca cttttgcctg
     7261 atttgaaatt gatacctttc taatcgtcac ctggatgaaa ataattcatt gatattcaaa
     7321 attaatttcc tacaggaatg cagaggcggc gggaagatat gcccttaatg ccactgaaaa
     7381 accacataat ctgtacagca ataaaagtca cggcctaata tggctaacaa acaatcaatt
     7441 gtgatatagt tcacaaaatt aatgaaacaa acagagtgtt tcatttttgt gttctgcaag
     7501 ccccgcgata gccagagtgt accacgcctc ccgtgaacaa cgccgcgctg tccagggcat
     7561 cggctctttt cagaggaatt gtttgatggc taccctcacc actggcgtgg ttcttcttcg
     7621 ctggcaactt cttagtgccg taatgatgtt tctggccagc acactcaaca tccgttttcg
     7681 tcggtctgat tatgtcgggc ttgcggtgat cagcagcggt ctgggcgttg tttccgcctg
     7741 ttggttcgca atggggttgc ttggcatcac aatggcggac atcaccgcta tctggcacaa
     7801 catcgagtcg gtgatgatag aagagatgaa tcagacaccg ccacaatggc caatgatttt
     7861 gacctgatac gtagaagcct ccataacgga ggcttctttt ttatggctgg cagatgcttt
     7921 aatcatccac cttaaaacaa tataacctat tgttttaatg acaaatcaga acggaatgtc
     7981 atcatcaaag tccatcggcg gctcgttaga cggcgctgcc ggagcggact gctgcgggcg
     8041 agactgcgcg ccgccgctga actgattgcc accctgcggc tgctgaggct gaccccaacc
     8101 gccctgcggc tgaccaccac cgatattacc acctgccgga gcgccaccac cctgacgacc
     8161 acccagcatc tgcatggtgc cgccaacgtt caccacgact tctgtggtgt agcgatcctg
     8221 gccggattga tcggtccatt tgcgggtacg cagctgacct tcgatataaa cctgagaacc
     8281 tttacgcaga tattcgctgg ccacttctgc cagtttgccg aacagcacaa cgcggtgcca
     8341 ttcagtctgt tctttcatct cgccggtcgc tttatcacgc caggattcgg aagtagccag
     8401 cgtaatgttg gcaactgcgc caccatttgg catgtagcgt acttccgggt cctgacccag
     8461 attaccaacg agaataacct tgtttacgcc tctgctggcc atgttcgtgt ctcctgaaaa
     8521 aaatcgttct gaataagtgt aaacgcgcga ttgtaccatt accaatagcg cttttactat
     8581 gttgtgacct cggttccggg aaacaaacct ggccagacat tgttacacaa cactccggat
     8641 aatgcattcc aatactgtat attcattcag gtcaatttgt gtcataatta accgtttgtg
     8701 atcgccggta gcaccatgcc accgggcaaa aaagcgttta atccgggaaa ggtgaatgga
     8761 taagatcgaa gttcggggcg cccgcaccca taatctcaaa aacatcaacc tcgttatccc
     8821 ccgcgacaag ctcattgtcg tgaccgggct ttcgggttct ggcaaatcct cgctcgcttt
     8881 cgacacctta tatgccgaag ggcagcgccg ttacgttgaa tccctttccg cctacgcgcg
     8941 gcagtttctg tcactgatgg aaaagccgga cgtcgatcat attgaggggc tttctcctgc
     9001 catctcaatt gagcagaaat cgacgtctca taacccgcgt tctacggtgg ggacaatcac
     9061 cgaaatccac gactatttgc gtttgttgtt cgcccgcgtc ggcgaaccgc gctgtccgga
     9121 ccacgacgtc ccgctggcgg cgcaaaccgt cagccagatg gtggataacg tgctgtcgca
     9181 gccggaaggc aagcgtctga tgctactcgc gccaatcatt aaagagcgca aaggcgaaca
     9241 caccaaaacg ctggagaacc tggcaagcca gggttacatc cgtgctcgta ttgatggcga
     9301 agtctgcgat ctttccgatc cgccgaaact ggaactgcaa aagaaacaca ctattgaagt
     9361 ggtggttgat cgcttcaagg tgcgtgacga tcttacccaa cgtcttgcgg agtcgtttga
     9421 aaccgcgctg gagctttccg gtggtacagc ggtagtggcg gatatggacg acccgaaagc
     9481 ggaagagctg ctgttctccg ccaacttcgc ctgcccaatt tgcggctaca gtatgcgtga
     9541 actggagccg cgactgtttt cgtttaacaa cccggcaggt gcctgcccaa cctgtgacgg
     9601 ccttggcgta cagcaatatt tcgatcctga ccgcgtgatc caaaaccccg agctgtcact
     9661 ggctggcggt gcgatccgtg gctgggatcg ccgcaacttc tattacttcc agatgctgaa
     9721 atcgctggca gatcactata agttcgacgt cgaagcgccg tggggcagcc tgagcgcgaa
     9781 cgtgcataaa gtggtgttgt acggttctgg caaagaaaac attgaattca aatacatgaa
     9841 cgatcgtggc gatacctcca tccgtcgtca tccgttcgaa ggcgtgctgc acaatatgga
     9901 gcgccgttat aaagagacag aatccagtgc ggtacgtgaa gaattagcca agtttatcag
     9961 caatcgccca tgcgccagct gcgaagggac gcgtctgcgt cgggaagcgc gccacgttta
    10021 tgtcgagaat acgccgctgc ctgctatctc cgacatgagc atcggtcatg cgatggaatt
    10081 cttcaacaat ctcaaactag ctggtcagcg ggcgaagatt gcagaaaaaa tccttaaaga
    10141 gatcggcgat cgtctgaaat tcctcgttaa cgtcggcctg aattacctga cactttcccg
    10201 ctcggcagaa acactttccg gcggtgaagc ccagcgtatc cgtctggcga gccagattgg
    10261 tgcgggcctg gttggcgtta tgtatgtact ggacgagccg tctatcggcc tgcaccagcg
    10321 cgataacgag cgcctgttgg gtacgcttat ccatctgcgc gatctcggta ataccgtgat
    10381 tgtggtggag catgacgaag acgcaattcg cgccgctgac catgtgatcg atatcggtcc
    10441 tggtgcgggt gttcacggcg gtgaagtggt cgcggaaggt ccactggaag cgattatggc
    10501 ggtgccggag tcgttaaccg gacagtacat gagcggtaaa cgcaagattg aagtgccgaa
    10561 gaaacgcgtt ccggcaaatc cggaaaaagt gctgaagctg acaggcgcac gcggcaacaa
    10621 cctgaaggac gtgacgctca cgctgccagt cggtctgttt acctgcatca caggggtttc
    10681 aggttccggt aaatcgacgc tgattaacga cacactgttc ccgattgccc aacgccagtt
    10741 gaatggtgcg accatcgccg aaccggcacc gtatcgcgat attcaggggc tggagcattt
    10801 cgataaagtg atcgatatcg accaaagccc aattggtcgt actccacgtt ctaacccggc
    10861 gacctatacc ggcgtgttta cgcctgtgcg cgaactgttt gcgggcgtac cggaatcccg
    10921 tgcgcgtggt tatacgccag gacgtttcag ctttaacgtc cgtggcgggc gctgcgaagc
    10981 ctgtcagggc gacggtgtga tcaaagtaga gatgcacttc ctgccggata tctacgtgcc
    11041 gtgcgatcag tgtaaaggta aacgctataa ccgtgaaacg ctggaaatta agtacaaagg
    11101 caaaaccatc cacgaagtgc tggatatgac catcgaagag gcgcgtgagt tctttgatgc
    11161 cgtacctgca ctggcgcgta agctgcaaac gttgatggac gttggcctga cgtacattcg
    11221 cctggggcag tccgcaacca cactttctgg tggtgaagcc cagcgcgtga agctggcgcg
    11281 tgagctgtca aaacgcggca ccgggcagac gctgtatatt ctcgacgagc cgaccaccgg
    11341 tctgcacttc gccgatattc agcaactgct cgacgtactg cataaactgc gcgatcaggg
    11401 caacaccatt gtggtgattg agcacaatct cgacgtgatc aaaaccgctg actggattgt
    11461 cgacctggga ccagaaggcg gcagtggcgg cggcgaaatc ctcgtctccg gtacgccaga
    11521 aaccgtcgcg gagtgcgaag catcacacac ggcacgcttc ctcaagccga tgctgtaatc
    11581 gttaaggccg ctttctgagc ggccttttcc tttcagagtt gtaccagcaa tttacgcttt
    11641 tcttccggta gtaaattcac tgcctgctga taagacgcat ccaccagata atagatttgc
    11701 gaatccggca gcgaaccgtc gagatacacg gtgctccagt gcgctttatt cagatggcgg
    11761 ctaggacgca catcgctgtg ctgctgacgt agcagctccg ccagctccgg gctggttttc
    11821 agcgaaacag ctgggcgatt ttctacttct ttcaccatcg caaacagtac atcttccact
    11881 ttgatctgcg tcgctttcca gtcgttatgc acgctctgtt ctgcgcctgg ttttgccatg
    11941 caatattgta gcaactccga aatggtcatt ttttactccc cttgtagtgt cgcgatgatg
    12001 cgacgcgatc cgccgtggat gcgatgttcc cccagccaga tgccttgcca ggtgccggtc
    12061 tgaatacgcc ctttatgtac cggcaataca agcgatgttc ccagcattga ggatttgata
    12121 tgagaaggca tatcgtctgc tccctcatag tcatgctcat aatttccgtt gtcgggaacg
    12181 gtgcggagga aaaaacgctc catgtcgtgg cgtacggtgg gatcgcagtt ctcattaagt
    12241 gtcagagagg cggaggtatg ttgcagcaac agatgcagta agccgatgtt aacgcgcggc
    12301 atatcagcca gctgattcag aatttcatcc gttaccagat gaaacccacg agatttggcg
    12361 ctaagcgtga gcgtcttttg ataccacatg tgctgctcct tgataaaact ctcttaatca
    12421 gtttgcagca agacagcgaa aggataaagg tgtgattaaa aaaacagcat tcgggagagc
    12481 gtcacgctct cccgctctgt cagtattctg aattgacgat cacctcttca ccaaacgcac
    12541 ccgcttgtgg caagggtttg taggtagagt tggaggcgcg cagaatgcgg ataccacgag
    12601 cgccgacatc gcgtgcggcg gtaatatcat tatcagaatc gccataaaaa attcggatat
    12661 ttttatcctg cagccattgc gattttgtat tttgccctgg tttatcgccc gcaaagatca
    12721 ccggattcat gttggtggca ggaatatgaa aattatccgc cagcgttttt gaaaccgttt
    12781 ctgttttcgt cggactacga ccagtcacaa agaagatcgc gtcaccgcgg cgtacatgca
    12841 tatcaatcag ctggcgagcg acctcttttg gaatgctgaa ttcatcccag ccattgttca
    12901 ttttttccca gaacacagga tttttcagat aatcttcgct ttctggcgag aaggtttttt
    12961 tgccgcgcca gaagcccgga ctggaaaaaa gtaccgtgtc atcgatatca aaccccaccg
    13021 ccattggcgg acgccctgcg aggctatttt caatttgtgc gaccgaaacc caatgaatgg
    13081 gtgcctgttc agcaagcctg gcaacgttag tcccagggtt aagcggtgaa ggagatgagg
    13141 ccagggcaac agcggaactg tttagagcaa acaataagca aacggcactg attgcctgtg
    13201 tgatcttgcg catatttttc cctaaatagt cagtatgttg aaacttttta ttgtgagatt
    13261 tgttgcaaaa accatctgac cataacgcca gctgccgggg aaaggaagga ttatctgcgg
    13321 tttttgtgat gaaaagcagg atgattatat ttaacccagt aaatacgttc ctgtcttttt
    13381 ttgtataaaa aatgtttatt actcgatgta agga
//
LOCUS       DAZUDJ010000100        13114 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.100, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000100 DAZUDJ010000000
VERSION     DAZUDJ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13114
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.100"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..584
                     /locus_tag="ACHY1N_004381"
     CDS             <1..584
                     /locus_tag="ACHY1N_004381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HFS4046577.1"
                     /translation="IKIFYSNFCNVQTLNAANNQLKYINLDFLTYLPSIKSLRLDNNK
                     ITHIDTNNTSDIGTLFPIIKQSKNLNFLNVSGKNNCPTMQLMLFNLFSPALKLNTGLA
                     ILSPGAFEVHSDGIDVDNELFHYPIKKAYTPYNIHTYKTEEVVNQRNIKVKNMTLDEI
                     NNTYCNNDYYNQAIREEPIDLLDRSFSSSSWPF"
     gene            908..2296
                     /gene="narU"
                     /locus_tag="ACHY1N_004382"
     CDS             908..2296
                     /gene="narU"
                     /locus_tag="ACHY1N_004382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter NarU"
                     /protein_id="HFS4046578.1"
                     /translation="MALQNEKNNRYLLRDWKPENPTFWENKGKHIARRNLWISVSCLL
                     LAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRW
                     TVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK
                     QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWV
                     PLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFA
                     MLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLF
                     LTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQA
                     QKEAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLT
                     WLVYGRRKFSQK"
     gene            2378..6118
                     /gene="narZ"
                     /locus_tag="ACHY1N_004383"
     CDS             2378..6118
                     /gene="narZ"
                     /locus_tag="ACHY1N_004383"
                     /EC_number="1.7.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase Z subunit alpha"
                     /protein_id="HFS4046579.1"
                     /translation="MSKLLDRFRYFKQKGETFADGHGQVMHSNRDWEDSYRQRWQFDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWEIQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPLIRKRLIELWREALKQHSDPVLAWASIMNDPQKCLSYKQVRGRGGFIR
                     SNWQELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFY
                     DWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTIAITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFINYCRRY
                     SDMPMLVMLEPRDDGSYVPGRMIRASDLVDGLGESNNPQWKTVAVNTAGELVVPNGSI
                     GFRWGEKGKWNLESIAAGTETELSLTLLGQHDAVAGVAFPYFGGIENPHFRSVKHNPV
                     LVRQLPVKNLTLVDGNTCPVVSVYDLVLANYGLDRGLEDENSAKDYAEIKPYTPAWGE
                     QITGVPRQYIETIAREFADTAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLIFCGC
                     VGQSGGGWAHYVGQEKLRPQTGWLPLAFALDWNRPPRQMNSTSFFYNHSSQWRYEKVS
                     AQELLSPLADASKYSGHLIDFNVRAERMGWLPSAPQLGRNPLGIKAEADKAGLSPTEF
                     TAQALKSGDLRMACEQPDSGSNHPRNLFVWRSNLLGSSGKGHEYMQKYLLGTESGIQG
                     EELGASDGIKPEEVEWQTAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMN
                     TSDMHPFIHPLSAAVDPAWESRSDWEIYKGIAKAFSQVCVGHLGKETDVVLQPLLHDS
                     PAELSQPCEVLDWRKGECDLIPGKTAPNIVAVERDYPATYERFTSLGPLMDKLGNGGK
                     GISWNTQDEIDFLGKLNYTKRDGPAQGRPLIDTAIDASEVILALAPETNGHVAVKAWQ
                     ALGEITGREHTHLALHKEDEKIRFRDIQAQPRKIISSPTWSGLESDHVSYNAGYTNVH
                     ELIPWRTLSGRQQLYQDHPWMRAFGESLVAYRPPIDTRSVSEMRQIPPNGFPEKALNF
                     LTPHQKWGIHSTYSENLLMLTLSRGGPIVWISETDARELTIVDNDWVEVFNANGALTA
                     RAVVSQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRVCPKPTHMIGGYAQL
                     AWGFNYYGTVGSNRDEFIMIRKMKNVNWLDDEGRDQVQEAKK"
     gene            6115..7659
                     /gene="narH"
                     /locus_tag="ACHY1N_004384"
     CDS             6115..7659
                     /gene="narH"
                     /locus_tag="ACHY1N_004384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009325 - nitrate reductase complex
                     [Evidence IEA];
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HFS4046580.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNV
                     ETKPGIGYPKNWEDQEEWQGGWVRDVNGKIRPRLGSKMGVITKIFANPVVPQIDDYYE
                     PFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     EAIQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNVIEAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLAN
                     MLSAGDTGPVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVAQVEEMYRYLAIA
                     NYEDRFVIPTSHREMAGDAFAERNGCGFTFGDGCHGSDSKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            7659..8354
                     /gene="narW"
                     /locus_tag="ACHY1N_004385"
     CDS             7659..8354
                     /gene="narW"
                     /locus_tag="ACHY1N_004385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0051131 - chaperone-mediated protein
                     complex assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HFS4046581.1"
                     /translation="MQILKVIGLLMEYPDELLWECKEDALALIRSDAPMLTDFTHNLL
                     NAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLDCRE
                     LPDYLPLYLEYLSVLPDDQAKEGLLNVAPILALLGGRLKQREAPWYALFDALLQLAGS
                     SLSSDSVTKQVNSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDV
                     APQYVDISAGGGK"
     gene            8351..9031
                     /gene="narI"
                     /locus_tag="ACHY1N_004386"
     CDS             8351..9031
                     /gene="narI"
                     /locus_tag="ACHY1N_004386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009325 - nitrate reductase complex
                     [Evidence IEA];
                     GO_function: GO:0008940 - nitrate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0019645 - anaerobic electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HFS4046582.1"
                     /translation="MIQYLNVFFYDIYPYICATVFFLGSWLRYDYGQYTWRASSSQML
                     DKRGMVIWSNLFHIGILGIFFGHLFGMLTPHWMYAWFLPVAAKQLMAMVLGGICGVLT
                     LIGGAGLLWRRLTNQRVRATSTTPDIIIMSILLIQCLLGLSTIPFSAQYPDGSEMMKL
                     VGWAQSIVTFRGGSSEMLNGVAFVFRLHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRR
                     YQIVRSRR"
     gene            9110..10003
                     /locus_tag="ACHY1N_004387"
     CDS             9110..10003
                     /locus_tag="ACHY1N_004387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HFS4046583.1"
                     /translation="MKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARELGH
                     SETAFLLHSDDSDVRIRYFTPTVEVPICGHATVAAHYVRAKVLGLGNCTIWQTSLAGK
                     HRVTIEKHNDDYRISLEQGTPGFEPPLEGETREAIINALHLTEDDILPGLPIQVATTG
                     HSKVMIPLKPEVDIDALSPDLAALSAISKQIGCNGFFPFQIRPGKNETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHNVLPHDGNVLCVKGHQGRALGRDGMIEVTVTIRDNQP
                     EKVTISGTAVILFHAEWAIEL"
     gene            complement(10099..10944)
                     /gene="nhoA"
                     /locus_tag="ACHY1N_004388"
     CDS             complement(10099..10944)
                     /gene="nhoA"
                     /locus_tag="ACHY1N_004388"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HFS4046584.1"
                     /translation="MTPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVL
                     LPREIQLDDQSLEEKLVIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPAL
                     PPRTHRLLLVELEEEKWIADVGFGGQTLTAPIRLVSDLVQTTPHGEYRLLQEGDGWVL
                     QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLT
                     NFHFTHYENGHAVEQRNLPDVVSLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTH
                     PEAGK"
     gene            11117..11686
                     /locus_tag="ACHY1N_004389"
     CDS             11117..11686
                     /locus_tag="ACHY1N_004389"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415979.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFS4046585.1"
                     /translation="MSRFIPIELHHASRLLNHGPTVMITSFDEQSQRRNIMAAAWSMP
                     VEFEPPRVAIVVDKSTWTRELIERNGKFGIVIPGVAATNWTWAVGSVSGREEDKFNCY
                     GIPVVKGPVLGLPLVEEKCLAWMECRLLPATSAQQKYDTLFGEVVSAAADARVFVEGR
                     WQFDDNKLNTLHHLGAGTFVTSGKRVTAG"
     gene            complement(11690..11917)
                     /gene="pptA"
                     /locus_tag="ACHY1N_004390"
     CDS             complement(11690..11917)
                     /gene="pptA"
                     /locus_tag="ACHY1N_004390"
                     /EC_number="5.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tautomerase PptA"
                     /protein_id="HFS4046586.1"
                     /translation="MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIAL
                     QQIQPESWQAIWDAEIAPQMEALIKKPGYSM"
     gene            complement(12016..13114)
                     /locus_tag="ACHY1N_004391"
                     /pseudo
     CDS             complement(12016..13114)
                     /locus_tag="ACHY1N_004391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT         3194 a         3348 c         3291 g         3281 t
ORIGIN      
        1 aaattaaaat attctatagc aacttctgca atgttcagac attaaacgct gctaacaacc
       61 agttgaaata tataaatctt gatttcctga cttatcttcc atctatcaaa agtttaagac
      121 tggacaataa taaaataacc cacattgata ctaataatac atccgatatt ggaactttat
      181 tccccataat aaaacagagc aaaaacttaa attttttaaa tgtttctggg aagaacaatt
      241 gccctactat gcagctcatg ttatttaatt tgttttcccc agcacttaag cttaatactg
      301 gcctggcaat tctttcgcct ggtgcatttg aagttcactc tgacggaata gatgtggata
      361 acgaattgtt tcactatcct attaaaaaag catatacccc atataatata cacacttaca
      421 agacagagga agttgtaaac cagaggaata taaaagttaa aaacatgacc ttagatgaaa
      481 taaacaatac ttactgtaat aacgattatt acaatcaggc aataagagag gaaccgatag
      541 accttctgga cagatcgttt tcctccagtt catggccttt ttagtgaata aatcatcact
      601 aattctataa gtgtctggtc ttgttgataa tatagttaat atgtaaccct ttagattcac
      661 gatctgaagg gttgaaacat gacatacgtt caaagattaa cccccgtttg aaggttagct
      721 tgttagttac atttagtaac acatatctgg ctacttaatc cccattctgc ccccgcggtt
      781 acgctttctt atctattctt tcaatcagca cttcacccaa ttcatcctta attctaataa
      841 ctggctattg cgccttacct cctgttttgt cttttttcat taccaatgtg tgcatgtgag
      901 gaacaatatg gcactgcaaa atgagaaaaa taatcgttat cttttacgcg actggaaacc
      961 agaaaatccg accttctggg aaaataaagg aaaacatatt gctcgaagaa acctctggat
     1021 atcagtcagt tgtctacttc ttgccttctg tgtctggatg ctatttagcg cagttaccgt
     1081 taatctcaat aaaatcggtt ttaattttac taccgatcaa ctctttttat taaccgcatt
     1141 accctccgtt tctggcgcat tattgcgtgt tccctactcc tttatggtgc ctatattcgg
     1201 tggacgccga tggacggttt ttagtactgc aatcctgatt attccttgcg tctggctcgg
     1261 aattgccgtg caaaatccga atactccttt tgggatattt atcgttatcg ctttgctatg
     1321 cggttttgca ggtgcaaact ttgcttcgag catgggcaat atcagtttct tctttccaaa
     1381 agccaaacaa gggagcgctc ttgggattaa tggcggatta ggaaacttag gtgtaagtgt
     1441 aatgcagctg gttgcaccgc tggtcatttt tgtacctgta tttgcctttc tcggcgtcaa
     1501 tggcgtaccg caggccgacg gttcggtgat gtcgctggcg aatgccgcat ggatttgggt
     1561 accgctactg gcgattgcca cgatcgccgc ctggtcaggg atgaatgata tcgccagttc
     1621 acgcgcctca attgccgacc agctccctgt cttacaacgc ctgcatctct ggctgctgag
     1681 cctgctttac cttgccacct tcggttcgtt tatcggtttt tctgcgggtt ttgccatgct
     1741 ggcaaaaacc cagttcccgg atgtgaatat tctgcgcctg gcgttctttg gcccatttat
     1801 cggtgccatc gcgcggtcgg ttggtggtgc tatttccgat aagttcggcg gcgtgcgggt
     1861 gacgttgatc aactttattt ttatggcgat tttcagtgcc ctgctgttcc ttaccttacc
     1921 gggcacaggc tccggtaatt tcatcgcctt ttacgccgta tttatggggc tgtttctgac
     1981 tgcgggtctg ggaagtggtt ctactttcca gatgatcgcc gtcatctttc gccagataac
     2041 catttatcgg gtaaagatga aaggcggtag tgatgagcaa gctcagaaag aagccgtcac
     2101 cgaaacggcg gcggctctgg gctttatctc agccattggc gcagtgggcg gcttttttat
     2161 tccgcaggcg tttggcatgt cgctcaatat gaccggctct ccggtcggcg cgatgaaagt
     2221 gtttttaatc ttctacatcg tttgtgtgct gctgacctgg ctggtttatg gtcggcggaa
     2281 gttcagccaa aaataagaga tcgatgcctg atgtacaacc gtgtcgcatc cgacaaggca
     2341 tcagatccca attcattcct ggagcaggag tcatgtcatg agtaaacttt tggatcgctt
     2401 tcgctacttc aaacaaaagg gcgaaacctt tgccgatggt cacggacagg tgatgcatag
     2461 caaccgcgac tgggaggaca gctatcgcca gcgttggcag ttcgacaaaa tcgtgcgttc
     2521 cacccacggt gttaactgta caggctcctg tagctggaaa atctacgtta aaaatggtct
     2581 ggtgacctgg gaaatccaac agaccgacta cccgcgcact cgccctgacc tgcccaatca
     2641 tgaacctcgc ggctgcccgc gtggcgcaag ttactcctgg tatctttaca gcgctaaccg
     2701 cctgaaatac ccgctcattc gtaaacgact gattgaactg tggcgcgaag ccctcaaaca
     2761 acacagcgat ccggtactgg cgtgggcatc gattatgaac gatccgcaaa agtgcctgag
     2821 ctacaaacaa gtgcgtgggc gcggcgggtt tatccgctcc aactggcagg aactaaacca
     2881 gctgattgcc gccgctaacg tctggaccat caaaacctac ggcccggatc gcgttgccgg
     2941 tttctcgccg atcccggcga tgtcgatggt ttcttacgcc gccggaacgc gttatctgtc
     3001 gctgcttggc ggcacctgtt taagtttcta cgactggtat tgcgacctgc cgcccgcctc
     3061 gccgatgacc tggggcgagc aaaccgacgt accggaatct gccgactggt ataactccag
     3121 ctacatcatc gcctgggggt ctaacgtacc gcagacacgt acgccggacg cccacttctt
     3181 taccgaagta cgctacaaag gcactaaaac catcgccatt acccctgact actctgaagt
     3241 ggccaaattg tgcgaccagt ggctggcacc gaaacaaggc actgatagcg ccctggcgat
     3301 ggcaatgggc catgtgattt taaaagagtt tcatctcgat aatcccagcg actactttat
     3361 caactactgc cgccgctaca gcgacatgcc gatgctggta atgctggagc ctcgcgacga
     3421 tggtagctac gttcccgggc gcatgatccg cgcatctgac ctggtggatg gactgggcga
     3481 aagcaacaat ccgcagtgga aaaccgtagc agttaatacc gcaggtgaat tggtagtgcc
     3541 gaacggttcg attggtttcc gctggggaga aaaaggcaaa tggaatctgg aatccattgc
     3601 cgccggtacg gaaaccgaat tgtcgttaac cctgctcggt caacatgacg ctgttgcagg
     3661 cgtggccttc ccctactttg gcggcattga aaatccgcat tttcgcagcg taaaacacaa
     3721 tccggtgctg gtgcgccaat tgcccgttaa aaacctgacg ttagtcgatg gcaacacctg
     3781 tccggtggtc agcgtttatg atttggtact ggcgaattac ggcctcgatc gcgggctgga
     3841 agatgaaaac agtgcgaaag attacgctga aatcaaaccg tacaccccag cctggggtga
     3901 gcaaattacc ggcgtgccgc gccagtatat tgaaaccatc gcccgtgaat ttgccgatac
     3961 cgcccataaa acgcatgggc gctcgatgat tatcctcggc gcaggtgtta accactggta
     4021 tcacatggat atgaactacc gtgggatgat caatatgctg atcttctgcg gttgtgtcgg
     4081 gcaaagcggt ggcggctggg cacactatgt cggccaggaa aaactgcgcc cacaaaccgg
     4141 ctggttgcca ctggcctttg cgctcgactg gaaccgacca ccgcgccaaa tgaacagcac
     4201 ctcgtttttc tacaatcatt ccagccaatg gcgctatgaa aaagtctctg ctcaggagtt
     4261 actttcaccg ctcgccgatg ccagtaagta cagcggtcat ctgattgatt tcaacgttcg
     4321 cgccgaacgt atgggctggc taccttctgc gccgcagctg gggcgtaacc cgctcgggat
     4381 taaagctgaa gccgacaagg ccggattatc ccccacagaa tttaccgccc aggcgctgaa
     4441 atcgggcgat ttacgtatgg cctgcgaaca accagatagc ggcagcaatc atccgcgtaa
     4501 tttgtttgtc tggcgctcta acctgcttgg ctcctccggc aaaggccacg agtatatgca
     4561 gaagtatctg ctggggaccg aaagcgggat tcagggcgag gaactcggtg ccagcgacgg
     4621 gatcaaaccg gaagaagtcg agtggcaaac tgcggcgatt gaaggcaagc tcgacctgct
     4681 ggtgacgctc gacttccgca tgtccagtac ctgcctgttc tccgatatcg ttctgcccac
     4741 cgccacctgg tacgaaaaag acgatatgaa cacctcggat atgcatccgt ttattcatcc
     4801 gctttctgcg gcggtcgatc cggcgtggga atcacgcagc gactgggaaa tctacaaagg
     4861 tatcgccaaa gcattttcgc aagtgtgcgt gggtcatctt ggcaaagaaa ccgacgtggt
     4921 attacaaccc ctactgcatg actctccggc agagctctca cagccgtgtg aagtgctcga
     4981 ctggcgcaaa ggcgaatgcg atctgattcc aggcaaaacc gcgccgaata ttgtggcggt
     5041 ggagcgcgac taccctgcta cgtatgaacg ctttacctcg ctcgggccat tgatggacaa
     5101 acttggcaat ggcggtaaag ggatttcgtg gaatacgcag gatgaaatcg atttcctcgg
     5161 caaactcaat tacaccaagc gtgatggccc ggcacagggg cgtccgctga ttgacaccgc
     5221 cattgacgct tcagaagtga ttctggcact ggcaccggaa accaacggtc atgttgcagt
     5281 caaagcgtgg caggcgctgg gcgagatcac cgggcgcgaa catacccatc tggcgctgca
     5341 caaagaggac gagaagattc gctttcgcga tattcaggcg cagccgcgta aaattatctc
     5401 cagccccacc tggtccggtc tggaaagcga tcacgtatcc tataacgcgg gatacaccaa
     5461 cgttcatgag ttaattccgt ggcgcacgct gtcgggacgc cagcagctct atcaggatca
     5521 tccgtggatg cgtgcttttg gtgaaagcct ggtggcttat cgcccgccta tcgacacccg
     5581 tagcgtcagt gagatgcgcc agataccgcc aaacggcttc ccggaaaaag cacttaactt
     5641 cctgacgccg caccagaaat ggggcattca ctcaacctac agtgaaaacc tgctaatgct
     5701 gacgctctct cgcggtggac cgattgtctg gatcagcgaa acagatgccc gagaactgac
     5761 cattgtcgat aacgactggg tggaagtatt caacgccaac ggcgcgctga ctgcccgcgc
     5821 ggtggtcagc caacgtgtac cgccgggcat gaccatgatg tatcacgccc aggaacgcat
     5881 tatgaatatt cctggttcgg aagtaactgg catgcgcggc ggcattcata actcggttac
     5941 ccgcgtttgc ccgaaaccga cgcatatgat tggcggttac gcgcagctgg cctggggctt
     6001 taactactac ggcaccgtcg gatcgaaccg cgatgagttc atcatgatcc gcaagatgaa
     6061 gaacgttaac tggctggatg atgaaggtcg cgatcaggta caggaggcga aaaaatgaaa
     6121 atccgttcac aagtcggcat ggtgcttaac ctcgacaaat gtatcggctg ccatacctgt
     6181 tcggtgacct gtaaaaacgt ctggaccggg cgcgaaggca tggagtacgc atggtttaac
     6241 aacgtcgaaa ccaaaccggg cattggttat ccgaaaaact gggaagatca ggaagagtgg
     6301 caaggcggct gggtccgcga tgtgaatggc aagatccgtc cgcgtctggg cagcaagatg
     6361 ggcgtaataa ccaaaatctt cgccaacccg gtggtgccgc agattgatga ttactacgaa
     6421 cctttcactt tcgactacga acatttgcat agcgcaccgg aaggcaaaca tatccctact
     6481 gctcgcccgc gctcgctgat tgacggtaag cggatggaca aagtgatctg ggggccaaac
     6541 tgggaagaac tgctgggcgg cgagtttgaa aaacgtgccc gcgaccgcaa cttcgaggcc
     6601 atacaaaagg agatgtacgg gcagtttgaa aacaccttca tgatgtacct gccgcgcctg
     6661 tgcgaacact gcctcaatcc cagttgcgtg gcgacctgcc caagcggcgc tatctacaaa
     6721 cgcgaagaag acggcattgt gctgattgat caggataaat gccgtggctg gcgtttgtgc
     6781 attagcggtt gtccgtacaa aaaaatctac ttcaactgga aaagcggcaa gtcagaaaaa
     6841 tgtatcttct gttatccgcg aattgagtca ggccaaccca ccgtgtgctc agaaacctgc
     6901 gtgggtcgca tccggtatct gggcgtgctg ctttacgacg ccgaccgcat cgaggaagcg
     6961 gcgagcaccg agcgcgaagt tgacctctat gaacgtcagt gcgaagtgtt cctcgatcca
     7021 cacgatccct cagtgatcga ggaagccctg aaacaaggta ttccacaaaa cgtgattgaa
     7081 gctgcccagc gttcgcctgt ctacaaaatg gcgatggact ggaaactggc gctaccgctg
     7141 caccctgaat atcgcaccct gccgatggtc tggtacgttc ctccgctgtc gccgattcag
     7201 tcctacgcag atgcgggcgg tttgccgaaa agcgaaggcg tgctgcccgc catcgaaagc
     7261 ctgcgtattc cggtgcaata tctcgccaat atgttgagtg ccggcgatac cggtccggta
     7321 ctgcgggcgc tgaaacggat gatggcgatg cgccactata tgcgttcaca aaccgtggaa
     7381 ggcgttactg atactcgtgc catcgacgaa gtaggcctga gcgtcgccca ggtcgaagag
     7441 atgtatcgtt acctcgccat tgccaactat gaagatcgtt ttgtcatccc gacgagccat
     7501 cgggaaatgg cgggcgatgc cttcgcagaa cgcaacggct gcggttttac ctttggcgac
     7561 ggttgccacg gttcggacag taaattcaac ctgttcaaca gtagccgtat cgatgccatc
     7621 aacatcaccg aagtgcgcga caaagcggag ggcgaataat gcagatcctc aaagtgatcg
     7681 gcctgttgat ggagtatccg gacgagctgt tgtgggaatg caaggaggac gcgctggcgt
     7741 tgatccgcag cgacgcgccg atgcttacgg atttcaccca caacctgctt aacgcgccgc
     7801 tgctggataa acaggccgaa tggtgcgaag tgtttgaccg tggacgtacc acatcgctgc
     7861 tgctgttcga acatgttcat gccgagtccc gcgatcgcgg ccaggcaatg gtggacctgc
     7921 tggcggagta tgaaaaggtc ggcctgcagc tggattgtcg ggaactgccc gattatctac
     7981 cgctgtatct ggagtattta agcgtactgc ctgacgatca ggcgaaagaa ggattgctca
     8041 atgttgcgcc gatcctcgcc ctgcttggcg gtcgcttaaa acaacgcgag gcaccgtggt
     8101 acgcgttgtt tgatgctctg ctgcaactgg cgggaagctc cctttcaagt gacagtgtca
     8161 caaaacaagt aaacagcgaa gagcgcgatg acacccgcca ggcgcttgat gcagtgtggg
     8221 aagaggaaca ggtgaagttt attgaagata acgccacggc gtgtgacagc tcgccgctta
     8281 atcaatatca gcgacgcttt agccaggatg tcgcgccgca atatgtcgac atcagtgcgg
     8341 gaggtgggaa atgattcagt atctgaacgt ctttttttac gatatctacc cgtacatttg
     8401 tgcgacggtg tttttcctcg gcagctggct gcgctacgac tacgggcagt acacctggcg
     8461 cgcctcctca agtcaaatgc tcgataaacg cgggatggtt atatggtcga atctgttcca
     8521 tatcggcatt ttggggatct tcttcgggca cctgttcggc atgttaacgc cgcactggat
     8581 gtacgcgtgg tttttgccag tggcagcgaa acaactaatg gcgatggtgc tcggcggtat
     8641 ttgcggtgtg ttgacattga ttggcggcgc aggactgctg tggcgcaggc tgacaaatca
     8701 gcgcgtgcgt gcaacttcca ctacgccgga tattatcatc atgagcattt tgctgatcca
     8761 gtgtctgctg gggctaagta ccataccgtt ttcagcacag tatcctgatg gtagcgaaat
     8821 gatgaagctg gtgggttggg cgcaaagcat tgtcactttc cgtggtggat cgtcagaaat
     8881 gcttaacggc gtagcgttcg ttttccgcct gcatctggta ttgggaatga ccatcttcct
     8941 gctcttcccg ttcaccagat tggtgcatgt gtggagcgcg ccgtttgagt actttactcg
     9001 tcggtatcag attgtgcgtt cgcggcgata atttcaccct ggccggatag cccttcgctc
     9061 tccggccact tgcaggctat gatagttttc cagtcacagg agaacgttaa tgaaaccgca
     9121 ggtgtaccac gtcgatgctt ttacctctca accatttcgc ggcaattctg ccggtgttgt
     9181 tttccccgcc gataatctta gcgaagcgca aatgcagctt atcgcccgcg agttaggcca
     9241 ttcggaaact gcttttctgc tgcacagcga cgacagcgat gtgcgcatcc gctactttac
     9301 gccaacggtt gaagtgccga tttgcggtca cgcgacagta gctgcgcact atgtacgtgc
     9361 gaaggtgtta ggtttaggaa attgcacgat ctggcaaaca tcgctggcag gaaaacatcg
     9421 cgtgactatc gaaaagcaca acgatgatta tcgtatttcg ctggaacaag gtacgccggg
     9481 ctttgagcca ccgctggaag gtgaaacacg tgaggcgatt atcaacgcgc ttcatctcac
     9541 tgaagacgat attttgccgg gcttgccaat tcaggtcgca acaacaggac actcaaaagt
     9601 gatgatcccg ttgaaaccgg aagtggatat cgacgccctt tcgcctgatc ttgctgcgct
     9661 gagcgctatc agcaaacaga ttggctgcaa tggtttcttc ccgttccaga tccgcccagg
     9721 caaaaacgaa accgatggtc gtatgttctc gcctgcgatt ggtattgtgg aagatccggt
     9781 gactggcaat gccaatggcc cgatgggtgc atggttggta catcacaacg tattgcccca
     9841 cgatggcaac gtgttatgtg ttaaaggcca tcaggggcgc gcattggggc gtgacggcat
     9901 gattgaagtg acggtgacaa ttcgtgataa ccaaccggaa aaagtcacca tttcaggcac
     9961 agcggtgatt ttgtttcatg ccgaatgggc aattgaactc tgaaaccgtt gcctgatgcg
    10021 cttcgcctgt caggtctaca accgagctaa tgtatgccgg ataaggcgtt tacgccgcat
    10081 ccggcaacct gacataaatt attttcccgc ctccggatgc gtatcaaacg ccgccatcac
    10141 cagcgctaac tcatccacag taaagccatg tttcgcatca tccacgccca gaccaaactg
    10201 ttcctgcatc acggcatata acgacaccac atccggtaga tttcgctgct ccaccgcgtg
    10261 cccattttca taatgggtaa aatgaaaatt ggtcagcgtt agcttgccac cgtccggcaa
    10321 atggcggcac atcagcaaat gatggcgaaa atgcgactgc ggccagtgcg ccgaccagaa
    10381 attgcccatc acataatcgc tttgttgctg ctcgcagaga tcaaaacggt acatcgactg
    10441 ccaatgctga tgatgattaa actgcaacac ccaaccatca ccctcctgca acaaccgata
    10501 ctctccgtgt ggcgtggtct gcacgagatc ggaaactaaa cgaatcggcg cggttagcgt
    10561 ctgcccaccg aaaccgacat cagcaatcca tttttcctct tccagttcca ccaacagcaa
    10621 acgatgggtg cgcggcggta atgctggcgg atttgataac actacgcgcc ctaacaagct
    10681 gcgaacgtta aaccccagct cgcgtaacac ccgctcaaac acgccattct gctcaaaaca
    10741 gtaaccgcca cgacgggcta tcaccagttt ctcttccagc gattgatcat caagctgtat
    10801 ttccctcggc agcaaaacgt caaggttttc aaacggaata gtgcaattgt gtttcaggtg
    10861 caatgcacga agcgtatcaa tattgaccgc agcagctccc gaccagttaa tacgggcaaa
    10921 atagtgattc agaatgggcg tcatcaggcg tttcccttag tggttttctc aacttataac
    10981 ctggaataga cgccgcaccg gctattttgt gcgatcgcgg acatgcatca cgtttgcaaa
    11041 tcgccaatcc cgttaatttc gttacttatt gcgttacgga ctacgcttaa aaaaaccttc
    11101 ttcgcgaggc gataccatga gccgattcat ccccatagaa ttacaccatg ccagccgtct
    11161 gttaaatcat ggcccaactg tcatgatcac cagtttcgat gagcaatccc agcggcgtaa
    11221 cattatggca gcagcctggt caatgccggt ggagtttgaa ccgccacgcg tggcgattgt
    11281 ggtagataaa tcgacatgga ccagggagtt gattgaacgt aacggtaaat ttggcatcgt
    11341 tatcccgggc gttgcagcaa ctaactggac gtgggcagtg ggaagcgtgt cgggtcgtga
    11401 agaagataaa tttaattgct atggcattcc ggtggtgaaa ggtccggtgc ttggtttgcc
    11461 acttgttgaa gagaaatgcc tggcgtggat ggagtgccgc ctgctacctg cgacttctgc
    11521 gcaacaaaaa tacgacacgc tgtttggcga ggtggtatca gcagcggcag acgcacgggt
    11581 atttgtcgaa ggccgctggc agtttgatga taataagctc aatacgttgc atcatttagg
    11641 tgctggcacg tttgttacta gcggcaagcg tgttacggca ggttaagcat tacatgctgt
    11701 aaccgggttt ctttatcaaa gcctccattt gaggcgcgat ttcggcatcc cagatagctt
    11761 gccaagattc tggttgaatc tgctgtagag caatgcttat cgaactgtct ttactgttca
    11821 gatggcgaat aataacgtcg gtaatatctg cagcaagtgc tgctttttgt tgttcgtcca
    11881 gttcacgcgg aaagcattta atgtcgatgt gcggcatgat tacgctcctt ttgaaagatg
    11941 tcagtaaaat taacacacat tgtgaatgtc atgtgtccgg taaagcgttt atacgacaat
    12001 aatgccaggg caagattacg aaagccttct ccccgcaagg actgacgcca ggtagtttct
    12061 gtccatggct gcttttcgca tcttacgtct taaccctgcc ttgaatacct tatcattcgt
    12121 caaaatatta atagcaatgt gccgtatccc tgaaaataat tctgctgcat ttccttttct
    12181 tattttgcag tcgtcttcat tcattaccac gtccagacgc cagtgcagct tattctccac
    12241 gtgccagtgg tttcggattg ctgtggcgaa cttctctgcg gttaaatcag cagaactgat
    12301 ataatatctg accgtcattt ctggctcttt cttttgttct gctattatgg accgaaagga
    12361 gactgccacg cataatttct tcagcccttt ccattcaaac gtgaaatcaa taagttcatc
    12421 agggacatcg caaacaatat gaagacggat ttcttctctg ccgtgactct tttcactcat
    12481 tgcgtaactg tcatgctctg gattatttaa ttctttcagc ggaaattttt cctcaaaggc
    12541 tttatttagc cgcccctggt ttccttttac cgcgaataaa taatcacctc cctgtttttg
    12601 tatcttttct gcaatatctt tctggcagcc catcgcatca gttgtgatga tttttccttt
    12661 aatatccatc atgttaagaa gttcaggaat ggctgtaatc tcattggatt tctcatccgt
    12721 cttgatctgt ccgaggacca gactatgcat tgttgagaac gcactaatga catgaatcgc
    12781 tcccctgcga cgactcttgt cataagagtg ccggagcgtt tttccatcaa ttgcaatgac
    12841 gtctttatca tctgaagaat ggcagtcacg catccagtta ataaagcact cgtgaaattt
    12901 tgcaggactg atacaggata caactctggc aatgatatcg tgaaaaggaa taccattttc
    12961 aaaatcacca tatcacttca aaacatcggg atgtgtttcc ccaaaatcct ctatatcttc
    13021 ccagccttct gcaccagaaa taacggcaca aatagtcaac agtagaatat ccgataattt
    13081 atgttccact ttccaggctt gtctgtaatc gggg
//
LOCUS       DAZUDJ010000101        13001 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.101, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000101 DAZUDJ010000000
VERSION     DAZUDJ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13001
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.101"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..293
                     /locus_tag="ACHY1N_004392"
     CDS             <1..293
                     /locus_tag="ACHY1N_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000077650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein TrbC"
                     /protein_id="HFS4046587.1"
                     /translation="QYDTDIESRANELWKKAVHTINNTTREERRVCYITLNRPEEEHS
                     DPEDIPSVKAILNTLLPLEILLPVAENNKSQTINNDHPQKSCGAQPTTDEKY"
     gene            complement(514..3234)
                     /locus_tag="ACHY1N_004393"
     CDS             complement(514..3234)
                     /locus_tag="ACHY1N_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFS4046588.1"
                     /translation="MNAIIPKKRRDGKSSFEDLIAYTSVRDDVPEDELRPDTEMKAEI
                     PHRNRFRRLVDYATRLRNEKFVSLIDVMKDGSQWVNFYGVTCFHNCLSLESAAEEMQK
                     AADLAHFSKDDTDPVFHYILSWPAHESPRSEQLFDCVRHTLKSLELSKHQYVAAVHTD
                     TDNLHVHVAVNRVHPETGYINCLPWSQEKLSRACRELEIKHGFAPDNGCFVHAPGNRI
                     VRKTALVRERRNAWRRGKKQTFREYIVQMSIAGLREEPAQDWLSLHKRLASDGLYITM
                     QEGELVVKDGWDRAREGVALSSFGPLWTAEKLGRKLGEYQPVPTDIFSQVGTPGRYDP
                     EAINVDIRPEKVAETESLKQYACRHFAERLPEMARNGELESCLDVHRTLATAGLWMGI
                     QHGHLVLHDGFDKQQTPVRADSVWPLMTLDYMQDLDGGWQPVPKDIFTQVIPGERFRG
                     RNLGTQAVSDYEWYRMRMGTGPQGAIKRELFSDKESLWGYGLIQCRSLIEEMIADGDF
                     SWQACHEMFARKGLMLQKQHHGLVIVDAFNHELTPVKASSIHPDLTLSRAEPQAGPFE
                     IAAADIFERVKPECRYNPELAASDEVEPGFRRDPEIRRERREARAAAREDLRARYLAW
                     KEHWRKPDLRYGERLREIHAACRRRKAYIRVQFRDPQLRKLHYHIAEVQRMQALIRLK
                     ESVKEERLSLIAEGKWYPLSYRQWVEQQAAQGDRAAVSQLRGWDYRDRRSRNKDKRRT
                     TNVDRCVVLCEPGGTPLFNNVAKLEARLQKNGSVHFRDTRTGKNVCTDYGDRVVFYHH
                     TDRNELAEKLDLIAPVLFSRNGKLGFEPEGSYQQFNDVFAEMVAWHNAAGITGNGHFT
                     ITRPDVDLHRQRSEQYYREYIRQQTRLSVSHDDNYTLRQEKTWEPPSPGM"
     gene            complement(3246..3578)
                     /gene="mobA"
                     /locus_tag="ACHY1N_004394"
     CDS             complement(3246..3578)
                     /gene="mobA"
                     /locus_tag="ACHY1N_004394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization protein MobA"
                     /protein_id="HFS4046589.1"
                     /translation="MSEKKTRSGSEKRQKNVLIAVRFSPEEAEIVKEKAEKNGLTVST
                     LIRKTVLGKQINARIDEDFLKELMRLGRLQKHLFVEGKRTGDKEYAEVLVAITELANT
                     LRRDLMGR"
     gene            3810..4145
                     /locus_tag="ACHY1N_004395"
     CDS             3810..4145
                     /locus_tag="ACHY1N_004395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobC"
                     /protein_id="HFS4046590.1"
                     /translation="MASKKFYSDDDIQLAKAALSELPDLTAQRKTLRDFLDAIRDDII
                     VLVRTKGYTLADVRDTLKNAGYEVGEKALRDIIREAESKKPSRRSSSKTAPKKTDSGR
                     KDGIDMNNN"
     gene            complement(4231..5079)
                     /locus_tag="ACHY1N_004396"
     CDS             complement(4231..5079)
                     /locus_tag="ACHY1N_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HFS4046591.1"
                     /translation="MNQTLPTADLNTAGTTDIIPSMAIDRIIAQRNEGIALFMQAMEC
                     LATARRILLDASGDIFLYGFEDCVTDSVRCMDKPEEAKKNITRLADRKIWDRLMTYTG
                     MYTFMSSCQRDEWNSQLMSDTCPEITLDNVLATFRHLNASKMQTFEQELIDIWRKLSW
                     DYRTNNPCRLGKRIIIENLLYRWSNGRVTLDCSGREALDDLVRPFYLLEGRNVPDFRN
                     SIGAQYGEFLGNGDNIGELFEGEYFTVRGYQKGTVHIVFKRPDLVEKLNDIIARHYPG
                     VLPPRV"
     gene            5429..5624
                     /locus_tag="ACHY1N_004397"
                     /pseudo
     CDS             5429..5624
                     /locus_tag="ACHY1N_004397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001753860.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5658..5909
                     /locus_tag="ACHY1N_004398"
     CDS             5658..5909
                     /locus_tag="ACHY1N_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFS4046592.1"
                     /translation="MTGWELRIWRKSMLWSREKAAREFGVTQRTWHAWENAEQVDVTV
                     WRTTQALSVRDLLPHMQGMRKADIIRRLENELGETAGNV"
     gene            complement(5940..6185)
                     /locus_tag="ACHY1N_004399"
     CDS             complement(5940..6185)
                     /locus_tag="ACHY1N_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014358130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046593.1"
                     /translation="MRTTKPGKMPGFFVSRSRANSMTIAERLIQKGFDEGFKKGALEV
                     AREAACRLRDMGWTPERIQEATGLSGEELKKLFPDEQ"
     gene            complement(6185..7075)
                     /locus_tag="ACHY1N_004400"
     CDS             complement(6185..7075)
                     /locus_tag="ACHY1N_004400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HFS4046594.1"
                     /translation="MSKKKNTTTPTPHDAAFWSFLANPDVARDFLELHLPAEYRQLCD
                     LSTLKLEPATFVEPDLHQYASDILWSVKTTGGEDGYVYTLIEHQSTENLYMPFRMLRY
                     SVAAMQRHLEQHKTLPLVIPVLFYHGERSPYPYSMNWLDCFEEPALAAKIYTKPFPLV
                     DITVVDDNEIMNHRRMAALTLLMKHIRHRDMMELLDKLPQVMVEISDEQVRVLIHYIV
                     NAGDSVSPEFMRALAERLPQHEDKLMTIAERLEQKGRQEGALEKALAIACQLQKMGMT
                     PEQIKQATGLSEAELKNITH"
     gene            complement(7140..7406)
                     /locus_tag="ACHY1N_004401"
     CDS             complement(7140..7406)
                     /locus_tag="ACHY1N_004401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046595.1"
                     /translation="MRPSIIFATAEYVKRLREECLRENKPLHRHTRVRRQELAQDEIN
                     PDVLAMSGHIARRCSEQKRVRIPAMKVSEWGHLLRALEIERACH"
     gene            complement(7499..7933)
                     /locus_tag="ACHY1N_004402"
     CDS             complement(7499..7933)
                     /locus_tag="ACHY1N_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="post-segregation killing protein PndC"
                     /protein_id="HFS4046596.1"
                     /translation="MTVSSTISVFCRDGVFRTVYCHLHGEPTWNGRILHTHYATGQLA
                     EALVEHGDIRCLGPRCDKSAGHTLQNPVDGVTAYYGRDSGFRMDSEAREYRSFMEAIA
                     TESTEEVRFHYVFIDGYWKVMYRTPEGWKMKALALALRRCPK"
     gene            8039..8659
                     /locus_tag="ACHY1N_004403"
     CDS             8039..8659
                     /locus_tag="ACHY1N_004403"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046597.1"
                     /translation="MDLSDGAATATARGSCPGADAKVFDACGKKFCGWYIFPWTAAPC
                     CGRFSPRKVHSGKQAAGVAAEGLTAPSGAVALHTVRCAGSAVSGATGAARPERSLQAW
                     FFRHRTVAAARNRASGFGGDWRVRQQLPVGVGPTTGCRQAAGSRRVSPPPGIRTTETT
                     KQKNASHHDGQEGQRRRRGPPVFQAGVSLPGFSGGPAGHTPAGAGE"
     gene            complement(8661..9161)
                     /locus_tag="ACHY1N_004404"
     CDS             complement(8661..9161)
                     /locus_tag="ACHY1N_004404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFS4046598.1"
                     /translation="MSVVAPAVYVGTWHKYNCGSIAGRWFDLTTFDDERDFFAACRAL
                     HQDEADPELMFQDYEGFPVNMASECHINWAWVEGFRQARDEGCEEAYRLWVDDTGETD
                     FDTFRDAWWGEADSEEAFAVEFVSDTGLLADVPETVALYFDYEAYARDLFLDSFTFID
                     GHVFRR"
     gene            complement(9623..10220)
                     /locus_tag="ACHY1N_004405"
                     /pseudo
     CDS             complement(9623..10220)
                     /locus_tag="ACHY1N_004405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000978013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10217..10936)
                     /locus_tag="ACHY1N_004406"
     CDS             complement(10217..10936)
                     /locus_tag="ACHY1N_004406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001723065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HFS4046599.1"
                     /translation="MSARSRALIPLSAEQQAAMQAVAVTEQRRRQGRTLSAWPYASAF
                     FRCLNGSRRISLTDLRFFAPALTKEEFHGNRLLWLAAVDKLIESFGEVCVLPLPSDAG
                     HRLFPSVPFREGERRRQKTTLTEQKYSRQREREAERRELEYQTCFAQAQIDLAFHTPA
                     TVGSWLSRWSGVVEEHDLETIFWGWCGRFPSLSSFDRFFWQEEPLWRLIFEAGEAGRG
                     APVQVRALEQWMIPNKLENAI"
     gene            complement(10933..11181)
                     /gene="psiB"
                     /locus_tag="ACHY1N_004407"
                     /pseudo
     CDS             complement(10933..11181)
                     /gene="psiB"
                     /locus_tag="ACHY1N_004407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845953.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
     gene            complement(11176..11415)
                     /locus_tag="ACHY1N_004408"
                     /pseudo
     CDS             complement(11176..11415)
                     /locus_tag="ACHY1N_004408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858335.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11460..11946)
                     /locus_tag="ACHY1N_004409"
                     /pseudo
     CDS             complement(11460..11946)
                     /locus_tag="ACHY1N_004409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052646.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
     gene            complement(11906..12124)
                     /locus_tag="ACHY1N_004410"
     CDS             complement(11906..12124)
                     /locus_tag="ACHY1N_004410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046600.1"
                     /translation="MNYSGFEDMREQVAELANTMCDLRTTMNEMEQRYSDADTLPERL
                     VRQTLFRASHLFMKAYNEILELDYCFKD"
     gene            complement(12124..12807)
                     /locus_tag="ACHY1N_004411"
     CDS             complement(12124..12807)
                     /locus_tag="ACHY1N_004411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HFS4046601.1"
                     /translation="MSRFVLGNCIDVMARIPDNAIDFILTDPPYLVGFRDRSGRTIAG
                     DVNDDWLQPASNEMYRVLKKDALMVSFYGWHRIDRFMAVWIRAGFSVAGHLVFTKNYT
                     SKSAYVAYRHACAYILAKGSPARPRNPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNSIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DNRFEPEAA"
     gene            complement(12883..>13001)
                     /locus_tag="ACHY1N_004412"
     CDS             complement(12883..>13001)
                     /locus_tag="ACHY1N_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046602.1"
                     /translation="PSPFSDERPSSRFRGIALPSKRRRLRYSTVGLTRYRTR"
BASE COUNT         3021 a         3691 c         3317 g         2972 t
ORIGIN      
        1 cgcaatatga tacagatatc gaatcccggg caaacgaact gtggaaaaag gctgtgcaca
       61 ctatcaataa cacaaccagg gaagaacgcc gggtatgtta tatcacactg aatcgtccgg
      121 aagaggaaca ctctgatcct gaagatatac cttcagtgaa ggcgattctg aataccctgc
      181 tccccctgga gatactgtta ccggtcgctg aaaataataa atcgcagaca ataaataatg
      241 atcatcccca gaaatcatgt ggagcacaac caacaactga cgaaaaatac tgaaggaata
      301 caaatatttt ctggtgacca tatctgtcaa tcagactgta aaaccctgtt cactaagtcc
      361 ggggttttac ggcgcactgg ataagggccg cagacacggc ccttaattca gagttaaccg
      421 ggtataaact caattcagtg actactcccg cccttattga cgaaggttcc tgccgttttt
      481 gggctgaatc tttgcaccat cacttatccg ggcttacatt ccaggtgatg gtggctccca
      541 tgttttctcc tgccgtaacg tataattatc atcatggctc accgataaac gggtctgctg
      601 tctgatatat tcccggtaat actgctcact gcgttgacgg tgcaaatcca cgtccggacg
      661 agtaatggtg aagtgtccgt ttccggttat tcccgctgca ttgtgccagg ccaccatttc
      721 tgcaaacaca tcattaaact gctggtatga accttccggc tcaaaaccaa gctttccgtt
      781 gcggctgaac agaactggcg caattaaatc aagcttctct gccagttcat ttcggtccgt
      841 gtgatggtag aacacaaccc gatctccgta atccgtacag acattttttc ctgtccgcgt
      901 atccctgaaa tgaacacttc catttttctg aagacgagct tcaagttttg caacattatt
      961 aaaaagtggc gttcctccgg gttcgcagag tacgacacaa cgatcaacat tagttgtgcg
     1021 tcttttatcc ttattacgcg agcgacgatc acgataatcc cagccacgta actgcgatac
     1081 tgcagccctg tctccctgag ccgcctgttg ttccacccac tgccggtagg acaaaggata
     1141 ccacttaccc tccgcaatca gtgacaaccg ctcttccttc acactctcct tcagcctgat
     1201 cagcgcctgc atacgctgca cttccgcaat atggtaatgc agcttacgca attgtggatc
     1261 ccggaactgc acacggatat acgccttgcg ccgacggcag gcagcatgaa tttcccgtaa
     1321 ccgttctccg taacgtaagt cgggtttacg ccagtgctcc ttccatgcaa gataacgcgc
     1381 acgcaaatct tcccgcgcag ctgcacgggc ttcacggcgc tcacgacgaa tctcaggatc
     1441 gcgccggaag cctggttcca cttcatcact ggcagcaagt tccggattgt aacgacattc
     1501 aggcttcacc cgttcgaaaa tatctgcagc cgcaatttca aatggcccgg cctgaggctc
     1561 ggcacgggat aacgtcaaat caggatggat actgctggcc ttcaccggtg tcagctcatg
     1621 attaaacgca tccacaatca caagaccatg atgctgtttc tgcagcataa gccctttacg
     1681 cgcaaacatc tcatgacatg cctgccagct gaaatccccg tcagctatca tctcttcaat
     1741 caggctcctg cactgaataa ggccgtatcc ccacagactt tccttatcag aaaacagttc
     1801 gcgctttatt gctccctgtg gacctgtccc catccgcata cgataccatt cgtaatcact
     1861 gacagcctga gtaccaagat tacgtccccg gaaccgttct ccgggtataa cctgagtaaa
     1921 aatatccttc ggtacaggct gccatccacc atccagatcc tgcatataat ccagcgtcat
     1981 taacggccac acactgtctg cacgtactgg tgtctgttgt ttatcaaatc catcatgcag
     2041 taccagatgc ccgtgctgga tccccatcca taatccagcc gttgccagag ttctgtgcac
     2101 atccaggcaa ctttccagct caccatttct cgccatttcc ggtaagcgtt cggcaaaatg
     2161 acggcaggcg tactgtttca gactctccgt ttctgccact ttttccggcc ggatatcaac
     2221 gtttatggct tccggatcat aacgaccggg tgtccccacc tgactgaaaa tatctgtcgg
     2281 tacaggctga tattccccca gtttccgccc cagtttttca gctgtccata acggtccgaa
     2341 cgaactgagt gcaacacctt cccgcgctct gtcccagcca tccttcacca ccagttcccc
     2401 ttcctgcatc gtgatataca gaccatcact ggccagccgt ttatgcaaag ataaccagtc
     2461 ctgtgcgggc tcttcacgca gcccggcaat cgacatctga acaatatatt ccctgaacgt
     2521 ctgctttttc ccgcgtcgcc aggcattacg gcgctcacgt accagcgctg ttttgcgcac
     2581 aatacgattg cccggtgcat gcacaaagca gccattatcc ggcgcgaatc cgtgcttaat
     2641 ttcaagttca cggcatgcac gactgagttt ttcctggctc cacggaaggc aattgatata
     2701 gccggtttca gggtggacac gattcactgc aacatgtaca tgcaggttat ccgtgtctgt
     2761 atgaacagct gccacatact gatgttttga cagctcaagg gatttcaggg tgtgacgcac
     2821 acagtcaaaa agctgctcag aacgcggact ttcgtgcgca ggccaggaga gtatatagtg
     2881 aaaaacagga tctgtatcat ctttggaaaa atgagcaagg tctgctgctt tctgcatttc
     2941 ttcagccgca gattcaagag acaaacagtt atgaaagcag gtcacaccat agaaattcac
     3001 ccactgactg ccgtctttca tcacatcaat cagggaaaca aatttttcat tacgcagacg
     3061 tgttgcataa tcaacaagac gtctgaagcg gttccggtgc ggaatctcag ctttcatttc
     3121 cgtgtctggc ctgagttcat cttccggcac atcatcccgc actgaggtgt acgcaatcag
     3181 gtcttcaaaa gaagactttc cgtcgcgtct ttttttcgga atgatggcat tcatcagcga
     3241 ttatctcagc gtcccattaa atctcttcgc agagtattag caagctctgt aatagcaacg
     3301 agaacctctg catactcttt atctcccgtg cgttttcctt ccacaaacag atgtttctgc
     3361 aggcgaccaa gacgcatcag ctctttcaaa aaatcttcgt caatgcgggc atttatctgt
     3421 tttcccagca cagtttttct tatcagagtt gaaactgtca gtccgttttt ttctgccttt
     3481 tctttaacaa tctcagcctc ttctggtgaa aaacgaacag caatgaggac attcttttgc
     3541 cgtttctcac tgccacttcg ggttttcttc tcactcatgg tctgctcctt accggggtgt
     3601 cggggctaag ccctgaccag gtggtaatcg tatagccgtg cgtgcgcggt tatacgatta
     3661 cacatcctgt cccgtttttc aggcattata gcctgttatt tttgtgcatc atagtcttat
     3721 gcagacggca gaggcggggc gcagctctgc caggaggcag tttttgatga taaaatcaga
     3781 cttcaacatg aaacggagaa aaagtgccaa tggcttctaa aaaattttac tcagatgatg
     3841 acatccagct ggcaaaagct gctttatcag aattgccgga cctcaccgct caacgaaaaa
     3901 cattgcgtga ttttcttgat gccattcgtg atgacatcat tgtcctggta aggacaaagg
     3961 gttatacact ggcagatgtt cgtgacacgc tcaaaaatgc agggtatgaa gtaggagaga
     4021 aggcacttcg tgacattatt cgggaagcag aatcgaaaaa accatcccgc cgttcttcct
     4081 ctaaaacagc acctaaaaag acagattcag gcaggaaaga tggcatcgat atgaacaaca
     4141 attgatgtga caatgtcaca tcgtattctg agattatgat gattacagaa aaaaaagccc
     4201 cggcataaat accagggctt ttctgtttaa tcagactcgt ggcggcaata caccaggata
     4261 atgccgtgca ataatatcat tcagtttttc aacaaggtca ggacgcttaa agacaatgtg
     4321 tacggtccct ttctggtagc cacgcaccgt aaaatattcc ccttcaaaca actcaccgat
     4381 attgtcgccg ttcccgagaa attcaccata ctgcgccccg atgctgttcc tgaagtcagg
     4441 aacgttgcgt ccctccagca gataaaacgg acgtaccagg tcatccagtg cctcccgtcc
     4501 gctgcagtcc agcgtcacac gcccgttact ccagcggtac agcaggtttt caataatgat
     4561 tctcttgccc agacggcagg gattattggt tctgtaatcc catgacaatt tccgccagat
     4621 atcaatcagt tcctgttcaa atgtctgcat cttactggca ttcagatggc ggaatgttgc
     4681 cagtacattg tccagggtga tttcaggaca ggtgtcgctc atcagctggc tgttccactc
     4741 atcacgctgg catgaactca tgaaggtgta catgcccgta taagtcatca ggcgatccca
     4801 gattttccgg tcggcaagac gggtgatatt cttttttgct tcttccggtt tatccatgca
     4861 tcgaacggag tcagtcacgc agtcttcaaa cccgtagaga aaaatgtcac cggaagcatc
     4921 gagcagaatc ctgcgcgctg tcgccaggca ttccatcgcc tgcatgaaca gtgcaatacc
     4981 ttcgttacgc tgcgcgatga tgcggtcgat agccatagac ggaataatat ctgtcgtgcc
     5041 ggcagtattc aggtcagcag tgggtaaagt ctgattcatc atattgtctc ctcatcgtca
     5101 cggctgccgg gtcagcctgg tcatttcccg gaggagcgaa gctccttctg ccgtccactt
     5161 cacagggggt tcttcccgca gtggaccttt ccgatggggg acgctcacca cgtcacgggg
     5221 cagttgtccg ggggcagacg caaaagtttt tgacgcctgc ggcaaaaagt tttgtggctg
     5281 gtacatctct cccctggacg actgaaacgg gatgtggtcg tgtatgtacc cccggaaagt
     5341 ccgtctgcgg agaacgggcc gcagtgcggc ggcagacagg cagagacagc tgcgccatca
     5401 ggcgcagtgg ccttacacac cgtcaggtgt gcagggagcg ccgcatccgg cgcgactgaa
     5461 gaaaaacgac agcacaacaa tggcatgtgg tggtcactgg cgcaccactc ccgcacaggt
     5521 gaaaacagag aaaacagcac gacacctaca actaaaaagt gaaatttctt cactttttca
     5581 ctcttattta tcgcgctgac ctggtgatta tgatgataaa ataaagtgaa gttttttcac
     5641 tttttcaaag gtgttttatg accggctggg aactgcgaat ctggcgaaaa agcatgctct
     5701 ggtcacgcga aaaagcggcc agagaatttg gcgtgacaca gagaacatgg cacgcctggg
     5761 aaaatgcgga acaggtggat gtcaccgtct ggaggaccac ccaggcactt tcagtccgtg
     5821 atctgctgcc tcacatgcag gggatgcgca aggcagatat catcaggcgt ctggaaaatg
     5881 aactggggga aacggcaggg aatgtgtgag cgtgattcac agcctggcag aatgccaggc
     5941 tactgctcat caggaaacag ctttttcagt tcttcaccgg aaagtccggt tgcctcctga
     6001 atccgttccg gcgtccagcc catatcccgc agccggcagg ctgcttcccg cgccacttca
     6061 agcgcacctt tcttaaaacc ttcgtcgaaa cctttctgta taagacgttc tgcaatcgtc
     6121 atgctgtttg ctctgctcct gctgacaaaa aaacccggca ttttgccggg ctttgtggtt
     6181 ctcatcagtg agtgatgttc ttcagttcag cttcggaaag tccggtagcc tgcttaatct
     6241 gctccggcgt catccccatt ttctgaagct ggcacgcaat agccagggct ttttcaagcg
     6301 ctccttcctg gcgacctttt tgctcaagac gttcagcgat agtcatcagt ttatcctcat
     6361 gctgcggcag acgctcagcc agcgcccgca taaattccgg tgatacagag tcccctgcgt
     6421 taacgatgta atgaatcaga acacgcacct gctcgtctga aatttccacc atgacctgcg
     6481 ggagtttgtc cagcagctcc atcatgtcac gatggcggat atgcttcatc agcagcgtca
     6541 gtgcggccat ccggcgatgg ttcatgattt cattgtcatc aacgacagtg atatcaacca
     6601 gcggaaacgg ctttgtgtat attttagccg caagcgccgg ttcctcaaaa cagtccagcc
     6661 agttcatgct gtacgggtac gggctgcgct caccatgata gaacagcacc ggaatcacca
     6721 gtggcaatgt tttgtgctgc tccagatgtc tctgcatcgc cgccacactg taacgtaaca
     6781 tgcggaaagg catgtacaga ttttcggtgc tctggtgctc gatgagcgta taaacatagc
     6841 cgtcttcacc cccggtggtt ttcacactcc agaggatatc gctggcgtac tgatgcaggt
     6901 ccggctcaac aaaggtggcg ggttccagct tcagcgtgga caggtcgcac aactgccggt
     6961 actccgccgg aagatgcagt tccagaaaat ctctggcgac gtcgggattc gccaggaacg
     7021 accagaacgc ggcatcatgc ggcgtgggcg ttgtggtgtt tttcttctta ctcacggttc
     7081 ctcctggtga gatgtctgaa cgtatcctgc cgcctgcaca ggcagacggc aagggttaat
     7141 cagtggcagg cccgctcaat ttcaagcgcg cggagcaggt ggccccattc gctgactttc
     7201 atggcgggga tacgtacccg cttctgctca ctgcagcgtc tggcgatatg accgctcatc
     7261 gccaggacgt ccgggttaat ctcatcctgt gccagctcct gacgtctgac gcgggtatgg
     7321 cggtgcaggg gtttattctc ccgcaggcac tcttcacgca gacgctttac atactcggcg
     7381 gttgcgaaga taatggatgg tctcatggca taatctccat agatagtgat tgagatgccg
     7441 gacttccgta cggggaagcg ccggcggaga aaggcagggt ttatcgccct gccttttttc
     7501 atttcggaca gcggcgcagt gccagcgcga gcgctttcat cttccagcct tccggcgtgc
     7561 ggtacatcac cttccagtag ccgtcgatga acacataatg gaagcgcacc tcttcagtgc
     7621 tttcagtggc aatagcctcc atgaaagaac ggtactcacg cgcctcactg tccatccgga
     7681 aaccactgtc acgtccgtaa taagccgtca caccgtccac cgggttctga agcgtatgcc
     7741 cggcggattt gtcgcaacgg ggaccgaggc aacggatatc tccgtgttca accagggctt
     7801 cggccagctg accggtggca tagtgggtat gcaggatgcg accgttccag gtcggctccc
     7861 cgtgcaggtg gcagtaaacg gtacggaaca ccccgtcgcg gcaaaaaacg gaaatcgtgc
     7921 tgctgactgt catgaaaacg tctccttctg ctgaatcagg tcgccgggcc gaccggttgc
     7981 tcccccggag gggcgaaagc cccttctgcc gtccacttct tcggggtttc tccccgcagt
     8041 ggacctttcc gatggggcag cgactgccac ggcacggggc agttgtccgg gggcagacgc
     8101 aaaagttttt gacgcctgcg gcaaaaagtt ttgtggctgg tacatcttcc cctggacggc
     8161 tgccccgtgt tgtggccgct tcagcccccg gaaagtccac agcgggaaac aggccgcagg
     8221 ggtggcggca gaagggttga ctgcgccatc aggcgcagtg gccttacaca ccgtcaggtg
     8281 tgcagggagc gccgtttccg gcgcgacagg ggcggcgcga ccggaacggt cgctgcaggc
     8341 ctggtttttc agacatcgga ccgtagcggc agcccgaaac cgcgccagcg ggttcggcgg
     8401 agactggcgg gtgcgccagc agctgcctgt cggagtcggg ccgacgaccg gatgccgcca
     8461 ggcagccggg agccgaaggg tgtccccgcc tccgggcatc agaacaacag aaacgacaaa
     8521 acagaaaaat gcctcacacc atgacgggca ggaagggcag cgccgcaggc gcggccctcc
     8581 tgtatttcag gcaggcgtaa gcctgcctgg gttttccggc ggcccggcag gccatacccc
     8641 cgccggagcg ggggagtaaa tcaccgacgg aacacatgac cgtcaataaa ggtgaaggag
     8701 tccaggaata aatcccgcgc atacgcctca tagtcaaaat agagcgccac cgtctccggc
     8761 acgtcagcca gcaggccggt atcactgacg aactcaaccg caaaagcctc ctcactgtca
     8821 gcctcgcccc accaggcatc gcggaaggtg tcaaaatccg tctcaccggt atcatccacc
     8881 cagagacgat aagcctcttc gcagccttca tcccgtgcct ggcggaagcc ttcaacccag
     8941 gcccagttga tatggcattc ggaggccata ttcaccggga acccctcata atcctgaaac
     9001 atcagttcag gatcggcttc atcctggtga agagcacggc aggcggcgaa aaagtcgcgt
     9061 tcatcatcaa acgtggtcag gtcaaaccag cggccagcga tgcttccaca gttgtattta
     9121 tgccaggttc caacgtatac agcaggtgca acaacagaca ttcccgaatc ctccatagtc
     9181 acatgttctg cgacaccggg cggtgccgtg cctccatctt tgccgggcct gcagggatgc
     9241 aagggcgcaa gggaagccgc agcccgacgc gcacggctga cgggagttgg agggtgagac
     9301 cgcgaaatct gagcgggtga acgaccggaa aatcacggca gacgggaagg agggaccggg
     9361 tgaccgcagc ggttcatctt accttgcatc ccgcccgcag aagcccggct acgatggagg
     9421 cacggcacag cccgcacacg acgctgaggc cacataactg aaaacccaca aggccatgcc
     9481 ccgcatggcc gggtaaaagc ggatccgccg gcgacttcct tattccggcg agtgcagagg
     9541 acacgccgca tgacctccag accacccctg atatgaaacg atcatgatcg gcgtgtccct
     9601 gcgaaaaata tacatgcctg gttcaccgga gaatatctgt gatatccaca agttttctgt
     9661 cgcacagcca gtcctgcgcc gcacgcacca cgctactgtc cggtttcacc gctttcagag
     9721 aagatgccag tcgtttgatc agcatcacca gttcccgtgt ctgtatgtcc ggcattgtct
     9781 ctggaagtgc agagggactc tcatttccga cgctcgtacc atgcgcttcc agtgtggcac
     9841 ggacaaacca ggcggcatcc accagttgct ggcgaatcca ggccagctcg gcatatctgt
     9901 cacgggctgc cattcgctca cccgacagcg ccttgctgat atggctgcgc accagattat
     9961 ccaggagttc ctgcgcttct tccggtgaaa agccacctgg tatctctgtg cgcaacagtc
    10021 ctttcctgta cagtagctgc agcagatcca atctgcgacc gcactgcaac tatcagtaca
    10081 taacggacaa tattcgcact ggcggtggtt tctgtatcat tcagaagttc ctccggatca
    10141 ttaccaccgg tattgcagag caacggcaac agaggtcgca tccacacggg aacctgatat
    10201 tgttcgtctg atttcatcat attgcgttct ccagcttgtt cgggatcatc cactgctcaa
    10261 gtgcacgtac ctgtaccggt gcaccacgac cggcctcacc ggcttcaaaa atcagccgcc
    10321 agagtggttc ctcctgccag aaaaaccggt caaatgatga cagtgatgga aaacgcccgc
    10381 accaccccca gaaaatcgtt tccagatcat gctcctcaac aacaccagac cagcgggaca
    10441 accagcttcc gaccgtggcg ggagtatgaa acgcaaggtc aatctgcgcc tgagcaaaac
    10501 atgtctggta ttccagttcc cgtcgttctg cctcacgttc ccgctggcgg ctgtatttct
    10561 gctctgtcag cgtggttttc tgacgacgac gctcaccttc acgaaaagga acggacggga
    10621 acagacgatg ccccgcatcg gatggcaggg gaagaacaca gacttcacca aaactttcaa
    10681 tcagtttatc cacggcagcc agccacagga gacggttgcc atgaaattcc tccttcgtca
    10741 gcgcaggggc aaaaaagcgg agatcggtca gcgaaatccg gcgactgcca ttcaggcagc
    10801 gaaagaaagc gctggcataa ggccatgctg aaagtgtgcg tccctgacga cgacgttgtt
    10861 ctgtgacagc cacagcctgc atggcggcct gttgttctgc gctgagggga atcagtgccc
    10921 gtgaacgtgc gctcatgcct gacctccttc tgccatcagg atatggatga tgtcgttaac
    10981 actgtatccc tgcgcatcaa gtgtcgcggc aagcgccagc gtgtgactga tagcgacagg
    11041 cgtgaagata tgttgcacct gaacgacggc gaaaggctgt ccaccacaat tcaccagaac
    11101 cagcatccag agctgagaga cgtctcccgg cgaacataat gccaggtgga aacgttcgtg
    11161 ggctggcgtg aaaccaagtt ccgccccggt tccggtcagt ttctgaatgg cggaggccag
    11221 gtgcggcggc agtacgccat cgtggcggtt aacgagtaac gtcgccagcc ggggcgcatc
    11281 cagccgcacg taaatgctga tccagcccgg atacttcagg ttacgctggt caacatccgt
    11341 ctcttccggc cagccctgcg ccagcagcag gtcgcgggca tgacgacaaa tcagtgcatt
    11401 cagcgtttta ttcatgattc atggtctccc tgaatcgccg cccggaggcg gcgataacat
    11461 cagtcgtttt cgtgcgtgtt gtttttcagc aggatgcggg cctgattaac caccgcctga
    11521 cggcgggtaa cgcattccgg gacggcgagg ccgtaatcac gggcggccca ttcacgcttc
    11581 cacaatgcct gttcagcggt ctgaatcagg gacgccagca gttcagcagg gacggtcacc
    11641 tggcggtttt cgctcacgtt gctgataatc tccatcgccg cggaggaaga aataccggac
    11701 tcagtccgct ggtcttccgg gatgtcctcc aggcgcgcca ggatggtcct gatttcatga
    11761 tcggccaggg aaatatccat tccgtcagcg agggcctgaa tctcttccgg ggaccagata
    11821 accagcatca acggcgtgtc tcccggatac tttgctgcca gcgcccggca gagcgtttcg
    11881 catgttccgt acatactctt tcccctcaat ctttgaagca gtaatccagt tccagtattt
    11941 cgttatatgc cttcataaac aggtggctgg cacgaaagag cgtctgacgc accagacgtt
    12001 ccggcagggt gtctgcatcg ctgtaccgct gctccatctc attcatggtt gtgcgcaggt
    12061 cgcacatggt gttggccagt tcagccacct gttcacgcat atcttcaaat ccgctgtaat
    12121 tcatcatgct gcctccggtt caaacctgtt atcatttgcg gccccctgct gcatggcccg
    12181 ttgcacggcg gcaaggcgtt gctgtccggc acggtgatac tgttcaagca gctcgatacc
    12241 aatataccgg cgtccggact gaagggcggc cacgcaggtt gaaccgctgc ctgcaaacgg
    12301 gtccagcaca attgagttcg ggtgtgtgaa gctctcaatc agcggttgca ggctggtaac
    12361 gggcttttcc gtcgggtgat ggcggttgcc cgaatatttc cagcccagca catccggcag
    12421 cgggttacgg ggccgggccg gactgccctt tgccaggatg taagcgcatg cgtggcggta
    12481 cgcgacatac gcagatttgg atgtgtagtt tttggtgaac acgaggtgcc ctgccacgct
    12541 gaatccggcg cgtatccaga ccgccataaa gcggtcaata cggtgccagc cgtagaagct
    12601 gaccatcagc gcgtcttttt tgagtacgcg gtacatctca ttgctggcag gttgcagcca
    12661 gtcatcatta acgtcaccgg caatggtgcg cccggaacgg tcacggaaac cgacgaggta
    12721 cggcgggtca gtcagtatga aatcaatggc gttatcagga atacgggcca taacatcgat
    12781 gcagttaccg aggacaaaac gggacataca aaactccttc tcttacagag ggcaccggga
    12841 gggcacccct gtggtgcccg ttacccgctg cctgtgggct gttcaccgcg tccggtaacg
    12901 ggtcaggccg accgtggaat accgcagcct tcgtcttttt gacggcaagg ctatgccgcg
    12961 aaagcggctt gaagggcgtt catcagaaaa gggcgacggg c
//
LOCUS       DAZUDJ010000102        12965 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.102, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000102 DAZUDJ010000000
VERSION     DAZUDJ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12965
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.102"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            226..807
                     /gene="mdaB"
                     /locus_tag="ACHY1N_004413"
     CDS             226..807
                     /gene="mdaB"
                     /locus_tag="ACHY1N_004413"
                     /EC_number="1.6.5.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone oxidoreductase MdaB"
                     /protein_id="HFS4046603.1"
                     /translation="MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRA
                     DSDYDVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRK
                     DPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
                     EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG"
     gene            838..1152
                     /locus_tag="ACHY1N_004414"
     CDS             838..1152
                     /locus_tag="ACHY1N_004414"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative quinol monooxygenase"
                     /protein_id="HFS4046604.1"
                     /translation="MLTVIAEIRTRPGQHHRQAVLDQFAKIVPTVLKEEGCHGYAPMV
                     DCAAGVSFQSMAPDSIVMIEQWESIAHLEAHLQTPHMKAYSEAVKGDVLEMNIRILQP
                     GI"
     gene            complement(1200..3092)
                     /gene="parE"
                     /locus_tag="ACHY1N_004415"
     CDS             complement(1200..3092)
                     /gene="parE"
                     /locus_tag="ACHY1N_004415"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFS4046605.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDG
                     LNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLASQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVK
                     HFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGD
                     MAEIEV"
     gene            complement(3121..3702)
                     /gene="yqiA"
                     /locus_tag="ACHY1N_004416"
     CDS             complement(3121..3702)
                     /gene="yqiA"
                     /locus_tag="ACHY1N_004416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HFS4046606.1"
                     /translation="MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYP
                     SDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL"
     gene            complement(3702..4529)
                     /gene="cpdA"
                     /locus_tag="ACHY1N_004417"
     CDS             complement(3702..4529)
                     /gene="cpdA"
                     /locus_tag="ACHY1N_004417"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004115 - 3',5'-cyclic-AMP
                     phosphodiesterase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HFS4046607.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQA
                     VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
                     SALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLL
                     ATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY"
     gene            complement(4554..4976)
                     /locus_tag="ACHY1N_004418"
     CDS             complement(4554..4976)
                     /locus_tag="ACHY1N_004418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HFS4046608.1"
                     /translation="MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQ
                     YRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY"
     gene            complement(4977..5606)
                     /gene="nudF"
                     /locus_tag="ACHY1N_004419"
     CDS             complement(4977..5606)
                     /gene="nudF"
                     /locus_tag="ACHY1N_004419"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HFS4046609.1"
                     /translation="MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQ
                     MSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEG
                     ESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA"
     gene            5811..7292
                     /gene="tolC"
                     /locus_tag="ACHY1N_004420"
     CDS             5811..7292
                     /gene="tolC"
                     /locus_tag="ACHY1N_004420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HFS4046610.1"
                     /translation="MKKLLPILIGLSLYGFSSLSQAENLMQVYQQARLSNPELRKSAA
                     DRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK
                     WRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLD
                     QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAAL
                     NVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTAST
                     GISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGA
                     SEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIV
                     DVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
                     NVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN"
     gene            7440..8111
                     /locus_tag="ACHY1N_004421"
     CDS             7440..8111
                     /locus_tag="ACHY1N_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417509.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HFS4046611.1"
                     /translation="MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSS
                     RSMGG"
     gene            8117..9277
                     /locus_tag="ACHY1N_004422"
     CDS             8117..9277
                     /locus_tag="ACHY1N_004422"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HFS4046612.1"
                     /translation="MERVSITERPDWREKAHEYGFNFHTMYGEPYWCEDAYYKLTLAQ
                     VEKLEEVTAELHQMCLKVVEKVIASDELMTKFRIPKHTWSFVRQSWLTHQPSLYSRLD
                     LAWDGTGEPKLLENNADTPTSLYEAAFFQWIWLEDQLNAGNLPEGSDQFNSLQEKLID
                     RFVELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCATEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVISNLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPNHPNLLPAYFAEDDHPQIEKYVVKPIFSREGANVSIIENGKTIEAAEGPYGEEGMI
                     VQQFHPLPKFGDSYMLIGSWLVNDQPAGIGIREDRALITQDMSRFYPHIFVE"
     gene            complement(9315..10103)
                     /gene="ygiD"
                     /locus_tag="ACHY1N_004423"
     CDS             complement(9315..10103)
                     /gene="ygiD"
                     /locus_tag="ACHY1N_004423"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HFS4046613.1"
                     /translation="MSSTRMPALFLGHGSPMNVLEDNLYTRSWQKLGMTLPRPQAIVV
                     VSAHWFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPVLAQHLVELLAPVPVT
                     LDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIML
                     VASGNVVHNLRTVKWHGDSSPYPWAMSFNEYVKANLTWQGAVEQHPLVNYLDHEGGAL
                     SNPTPEHYLPLLYVLGAWDGQEPITIPVDGIEMGSLSMLSVQIG"
     gene            10246..11019
                     /gene="zupT"
                     /locus_tag="ACHY1N_004424"
     CDS             10246..11019
                     /gene="zupT"
                     /locus_tag="ACHY1N_004424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HFS4046614.1"
                     /translation="MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIM
                     LLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLP
                     KSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG"
     gene            complement(11077..11247)
                     /gene="yqiD"
                     /locus_tag="ACHY1N_004425"
     CDS             complement(11077..11247)
                     /gene="yqiD"
                     /locus_tag="ACHY1N_004425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YqiD"
                     /protein_id="HFS4046615.1"
                     /translation="MFIAWYWIVLIALVVVGYFLHLKRYCRAFRQDRDALLEARNKYL
                     NSTREETAEKVE"
     gene            complement(11508..12161)
                     /gene="ribB"
                     /locus_tag="ACHY1N_004426"
     CDS             complement(11508..12161)
                     /gene="ribB"
                     /locus_tag="ACHY1N_004426"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HFS4046616.1"
                     /translation="MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS"
     regulatory      complement(12265..12413)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            12535..12825
                     /gene="ubiK"
                     /locus_tag="ACHY1N_004427"
     CDS             12535..12825
                     /gene="ubiK"
                     /locus_tag="ACHY1N_004427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis accessory factor UbiK"
                     /protein_id="HFS4046617.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRMSELENRSTEIKKQPDPETLPPTL"
BASE COUNT         3282 a         3459 c         3169 g         3055 t
ORIGIN      
        1 caaaaaaaac cgaaccaaac gtgtaaatta ttccggtgcg agtaagaatt atgaggaatg
       61 gctatcagta ttgtcatttt cagaaaatat ttatcctgca tcggtgagtc agagcaagat
      121 cagacttttg ctaaattcgc aaaagacttt gcacattttg ctaatttcac cgtaccgctc
      181 tgtgacgtac tatagtcggc aaacgtctca ccttgaggtt aaaaaatgag caacatcctg
      241 attatcaacg gcgcgaaaaa attcgcccac tccaatggtc aactgaacga caccctgacc
      301 gaagtcgcgg atggcacact gcgcgacctc gggcatgatg tccgcatcgt tcgcgccgac
      361 agcgactacg atgtcaaagc ggaagtacaa aactttctct gggctgatgt ggtgatctgg
      421 cagatgccag gctggtggat gggcgcgccg tggacagtga aaaaatatat tgatgatgta
      481 ttcaccgaag gtcatggaac gctgtatgcc agcgatggcc gtacccgcaa agatccgtca
      541 aaaaaatacg gttccggcgg cctggtacag ggcaaaaaat atatgctttc tctgacctgg
      601 aacgcaccaa tggaagcctt caccgaaaaa gatcaattct tccacggcgt tggcgtcgac
      661 ggtgtgtatc tgccgttcca taaagcaaac caattccttg gcatggaacc gctgccgaca
      721 tttatcgcta atgacgtgat aaaaatgcct gatgttcccc gctatactga agaatatcgc
      781 aagcatcttg tggaaatttt tggttaacta gagctcaggc tttagaagga gttaaccatg
      841 cttaccgtaa tcgcagaaat ccgtactcgt cctggtcaac atcaccgtca ggcggtattg
      901 gatcagtttg ctaaaatcgt tccaaccgta ctgaaagaag aaggttgcca cggctatgcg
      961 ccaatggtgg attgcgctgc tggcgtgagt ttccagtcta tggcaccgga ttctatcgtg
     1021 atgattgagc agtgggaaag catcgcgcat cttgaagcgc atctgcaaac cccgcacatg
     1081 aaggcgtaca gcgaagccgt aaaaggcgac gtgctggaga tgaatatccg catcctgcaa
     1141 cctgggattt aaacctgcct tgtttgcccg gccatcctga ccgggcaatg ttctttcctt
     1201 taaacctcaa tctccgccat gtcgcctttc tcttgcaacc agttgcggcg atcttccgag
     1261 cgtttcttcg ccagcagcat atccatcatc gcgtcagtac gctgatcgtc ttcatcatcg
     1321 atagtcaact gcaccagacg gcgagtgttc ggatcaagcg tggtttcacg caattgcatc
     1381 gggttcattt cccccagacc tttaaaacgc tggacgttcg gcttgccttt cttgcgtttt
     1441 aattgctcaa gtacgccctc tttctcttct tccgtcagcg cgtaataaac ctctttcccg
     1501 agatcaatac ggtagagcgg tggcagtgcg acgtaaacgt gaccgtgttt caccaacgcg
     1561 cggaagtgtt ttacgaacaa agcgcagagc agcgtggcaa tgtgcagacc atcagagtcc
     1621 gcatccgcga ggatacagat tttgccataa cgaagctggc tcagatcgtc gctgtcagga
     1681 tcgataccga tcgctaccga aatatcatgc acttcctgcg aggccagcac ttcgtcggaa
     1741 gaaacttccc aggtgttaag gatcttacct ttcagtggca tgatcgcctg atattcgcga
     1801 tcgcgcgcct gcttggcaga tccgcctgcg gagtcacctt ccacaaggaa cagttcggta
     1861 cggttaagat cctgcgcggt acagtcagcc agtttgccag gcagtgctgg gccgctggtc
     1921 agctttttgc gcaccacttt tttagccgca cgcatacggc gctgggcgct ggaaatcgcc
     1981 atctccgcca gcagctccgc cgcctgaacg ttctggttca gccacaggat aaaggcatct
     2041 ttcaccacgc ctgaaacgaa tgccgcgcat tgacgcgaag agagacgctc tttggtctgc
     2101 ccggcaaact gcggatcctg cattttcacc gacagaacat aggcgcagcg atcccagata
     2161 tcttccgccg acagcttcac gccgcgcggc agaatgttgc ggtattcaca gaactcacgc
     2221 atcgcgtcca acaggccctg acgcagacca ttaacatggg taccgccctg catcgttggg
     2281 ataaggttga cgtagctttc ggtcagcagt tcaccgcctt ccggcagcca cagtagcgcc
     2341 cagtccacag cttcagtatc gccagcgaaa ttaccgataa acggtttttc tggcagcgtc
     2401 ggtaaaccgt ttaccgcttc cgccaggtaa tcattcagac cgtcctgata gcaccagcgc
     2461 tgttcggtgt tgttgatctc atctttaaag gtaatctcaa cgccggggca cagtactgct
     2521 ttggccttca gcacatgcgt caggcgtgaa acagaaaaac gcgggctgtc aaagaaggtt
     2581 tcatccggcc agaagtgcac gctggtaccg gtattgcgtt taccgcaagt gccgacaacc
     2641 tgtaaatcct gcaccttttc gccattttca aaggcgatgt tataaacctg accatcgcgg
     2701 cgcacgttaa cttctacgcg cttcgacagg gcgttaacca ccgaaatccc cacgccatgc
     2761 aggccgccag agaactggta atttttgtta gagaatttac cgcctgcatg cagacggcaa
     2821 agaatcagtt caaccgccgg tacaccctct tccgggtgaa tatccaccgg catcccgcgc
     2881 ccatcgtcaa taacttctaa cgactggtca gcatgtaaga ttacatccac gcgttttgcg
     2941 tgacccgcca gtgcttcatc gacactgtta tcaataactt cttgccccaa atggttaggg
     3001 cgagtggtat cggtatacat ccccggacgg cggcgaaccg gctcaagccc ggtgagtacc
     3061 tcaatggcat cagcgttata agtttgcgtc atggtttaag ttagcaattc gagttgatcg
     3121 tcagagatgg tgcagaccaa gaaaatcgac gatcgggttg aaataatctt cgaagcccgt
     3181 gaatgcgtgg ttgccgcctt ctatgacagt ctggcggcag gaagcgtagt acgccaccgc
     3241 ctggcggtaa tccagcactt catctcccgt ctgttgcagc agccagatca aatccggcgc
     3301 ttccagcggg tcaatctgca tgactttgag atcgtaaata tggcgtgact ctagcacata
     3361 ttgctgcccg gtgtaggggt tctcgttctg accgagatag tccgtcagca gttcaaacgg
     3421 gcgcaccgcc gggtttacca ccactgcggg cagcataaaa cattgtgaca accaggtggc
     3481 gtaatatccc cccagtgacg aaccgacaat acccagcgaa tcgccgccat gttccaggac
     3541 aatggattcc agcagctctg ccgcgtcgga aggatacggc ggcaactgcg gaatgatcat
     3601 ctcaacgtca gggtgatgtt ccgccagcca gttttttaac aagctcgctt ttgcagagcg
     3661 cggcgagctg ttgaaaccgt gtaaataaag aagcgtagac atcagtagcc ttctgaagcg
     3721 gtatcaggtt ggaaacgtgt gtccgccagg cgatgcacct cggtggtcag cgtgccatca
     3781 gcatgtaact cgagagtacg ccagccgggc gcgatagtat ccagcgtaaa gttggaacag
     3841 tgcggcttaa actgcacaca ggtcgacggc gttgccagca ggcggcgacc gttccagtcg
     3901 agatccagct cctgatgaat atgaccgcac agcaagtatt tgacgtgcgg aaacttcgcc
     3961 agcacggtat ccagttcgcc cgcgttacgc agactgtgtt gatcgagcca actacaaccc
     4021 gcaggtagcg gatgatgatg cagcagcagc aacgtatggc gttctggcgc atcggccagt
     4081 ttacgttcca gccactcaag ctgaaactcg ctcagctcac cgtgcggcac gccaaacacc
     4141 tggctatcca gcaacaggat ttgccattgc tcaccaataa acacgcgctt cgccggggag
     4201 atacccgcat cctgtaacgc gctgtacatc gcgggctgga aatcgtggtt gcccggcagc
     4261 cagacgcagg gcgcacgaaa acttgcgatg ccttcagcga aatgctgata ggccgcagag
     4321 gattgatcct gcgctaaatc acctgtcgcg acaatcaggt cgaattcgtg ctgatgtgga
     4381 cgaatcgcct ccagcaccgc ctggtagctt tcccaggtgt ttacccctaa cagggcttcg
     4441 tgcttttgtg caaacaggtg agtatcggta atttgtaaaa tcctgactct ggcctcacca
     4501 gccagaggaa gggttaacag gctttccaaa tggtgtcctt aggtttcacg acgctagtaa
     4561 accggaatcg ccatcgctcc atgtgctaaa cagtatcgca accagtccgc taaaaactgg
     4621 ttaatttgat gcttttcgtc gcgttgatgc aactttttat taggataatc ataccgcgct
     4681 ttgaagcgaa aaatctgctg gcttgaacac acttcagcca ccatcgcgtc atgatacaga
     4741 cgcaccgtca ttgacggaag gctccagtaa ctgatcgcgg gcgcagtctg ttctattgtc
     4801 accagggtag tgtatcgggt cgattccaca atcgtcagcc gatattgtgc gtttgccacc
     4861 tgatagctta cagtttcgcc gggtgcgtca ttgcgcggta acaaacggcg caattgtgaa
     4921 aagttcatct cgcacaggcg catcatttca ggaaagtcag gtgtgtaacg cttcatttat
     4981 gcccactcat tttttaacgc ttgatgatgc agctgcagcc attgcaaagc gatgaccgac
     5041 gctgcgttgt cgattttccc ctcttctacc cactggtatg cctgttcccg gcttaccaca
     5101 tgaacgcgaa tatcttcgtt ttcatcagcc agaccatgaa taccgcttgc ggtcgtggcg
     5161 tccacttcgc ccaccataat tgacgaacgc tcactggtgc cccccgggct tgccaggaaa
     5221 cttaacaccg gtttggtccg tttgactatc agtcccgcct cttcaatcgc ttcgcgacgg
     5281 gcaacatctt ccacactttc accctcttct atcatcccgg caaccatctc cagtagccag
     5341 ggggtttcac tggtgtcgta tgcggcaatc cgaatctgct caatcagcac aacttcatca
     5401 cgcactgggt caaagggtag caagactgcg gcgtgaccgc gctcaaaaat ttccctccgt
     5461 acctcatgac tcatttgccc gttgaataaa cgatgacgaa atctataaag atctaatgaa
     5521 aaaaagccgc gataaagtgt ttctcgtgca ataatttcta catcgttttt gccaaatgta
     5581 acgggcaggt tgtctggctt aagcattgtt aatgtcctgg cactaatagt gaattaaatg
     5641 tgaatttcag cgacgtttga ctgccgtttg agcagtcatg tgttaaattg aggcacatta
     5701 acgccctatg gcacgtaacg ccaacctttt gcggtagcgg cttctgctag aatccgcaat
     5761 aattttacag tttgatcgcg ctaaatactg cttcaccaca aggaatgcaa atgaagaaat
     5821 tgctccccat tcttatcggc ctgagccttt atgggttcag ttcgttgagc caggccgaga
     5881 acctgatgca agtttatcag caagcacgcc ttagtaaccc ggaattgcgt aagtctgccg
     5941 ccgatcgtga tgctgccttt gaaaaaatta atgaagcgcg cagtccatta ctgccacagc
     6001 taggtttagg tgcagattac acctatagca acggctaccg cgacgcgaac ggcatcaact
     6061 ctaacgcgac cagtgcgtcc ctgcagttaa ctcaatccat ttttgatatg tcgaaatggc
     6121 gtgcgttaac gctgcaggaa aaagctgcag ggattcagga cgtcacatat cagaccgatc
     6181 agcaaacctt gatcctcaac accgcgaccg cttatttcaa cgtgttgaat gctattgacg
     6241 ttctttccta tacacaggca caaaaagaag cgatctaccg tcaattagat caaaccaccc
     6301 aacgttttaa cgtgggcctg gtagcgatca ccgacgtgca gaacgcccgc gcgcagtacg
     6361 ataccgtgct ggcgaacgaa gtgaccgcac gtaataacct tgataacgcg gtagagcagc
     6421 tgcgccagat caccggtaac tactatccag aactggcagc gctgaatgtc gaaaacttta
     6481 aaaccgacaa accacagccg gttaacgcgc tgctgaaaga agccgaaaaa cgcaacctgt
     6541 cgctgttaca ggcacgcttg agccaggacc tggcgcgcga gcaaattcgc caggcgcagg
     6601 atggtcactt accgacgctg gatttaacgg cttctaccgg gatttctgac acctcttata
     6661 gcggttcgaa aactcgtggt gccgctggta cccagtatga cgacagcaat atgggccaga
     6721 acaaagtggg cctgagcttc tcgctgccga tttatcaggg cggaatggtt aactcgcagg
     6781 tgaaacaggc ccagtacaac tttgttggtg ccagcgagca actggaaagc gcgcatcgta
     6841 gcgtcgtgca aaccgtacgt tcctccttca acaacattaa tgcatctatc agtagcatta
     6901 acgcctacaa acaagccgta gtttccgctc aaagctcatt agacgcgatg gaagcgggct
     6961 actcggtcgg tacgcgtacc attgttgatg tgttggatgc aaccaccacg ctgtacaacg
     7021 ctaagcaaga gctggcaaat gcgcgttata actacctgat taatcagctg aatattaagt
     7081 cagccctggg tacgttgaac gagcaggatc tgctggcact gaacaatgcg ctgagcaaac
     7141 cggtttccac taatccggaa aacgttgccc cgcaaacgcc ggaacagaat gctattgctg
     7201 atggttatgc gcctgatagc ccggcacccg tcgttcagca aacatccgca cgcactacca
     7261 ccagtaacgg tcataaccct ttccgtaact gatgacgacg acggggcttc ggccccgtct
     7321 gaacgtaagg caacgtaaag atacgggtta tctgccgcat tcttccccct tctcgcttca
     7381 atttcgacca gccatcctct attctgatgg gtatttacca ctggtcccgg aagacaaaaa
     7441 tgaaacggac aaaatccata cgccacgcat cgttccgcaa aaactggagc gcgcgccatc
     7501 tgacaccagt cgctctcgcg gttgccactg tttttatgct ggctggctgt gaaaagagtg
     7561 atgaaacagt gtctctctat caaaatgctg acgactgttc agctgcaaac ccaggcaaaa
     7621 gcgccgaatg taccaccgcg tacaacaatg cgctgaaaga agccgaacgt actgcgccga
     7681 aatacgccac ccgtgaagac tgtgttgctg aatttggtga aggtcagtgc cagcaggcac
     7741 cagcccaggc tggcatggca ccagaaaacc aggcgcaggc ccagcaatcc agcgggagtt
     7801 tctggatgcc gctgatggcc ggttacatga tggggcgtct gatgggcggc ggcgcgggat
     7861 ttgcacagca gccgctgttc tcctcgaaaa acccagccag cccggcttac ggtaaatata
     7921 ccgacgcgac gggtaaaaac tatggcgcag cccagccagg ccgcaccatg accgtaccga
     7981 agacagccat ggcaccaaaa ccggcgacca ccactaccgt tacccgtggc ggttttggtg
     8041 aatctgttgc caaacaaagc actatgcagc gtagcgcaac tggcacctct tctcgttcaa
     8101 tgggtggctg ataccgatgg aaagagtcag tattaccgag cgcccggact ggcgtgagaa
     8161 agcccacgaa tacggtttca attttcacac catgtacggc gagccgtact ggtgtgaaga
     8221 tgcttactac aagttgaccc tcgcccaggt tgaaaagctg gaagaagtca ccgccgaact
     8281 gcaccagatg tgcctgaaag tggtggaaaa agtgatcgcc agcgatgagc tgatgaccaa
     8341 attccgcatt ccaaaacaca cctggagttt tgtgcgccag tcatggctga cgcaccagcc
     8401 atcgctttat tcgcgtcttg atctggcgtg ggatggcact ggcgaaccta aacttctgga
     8461 aaataacgcc gatacgccaa cgtcactata cgaggcggcg ttctttcagt ggatctggct
     8521 ggaagatcag cttaacgccg gtaacttgcc ggagggcagc gaccagttta acagtctgca
     8581 agaaaaactg atcgatcgct tcgttgagct gcgtgaacag tatggcttcc agttgctgca
     8641 tctcacctgc tgtcgcgaca cggtggaaga tcgcggaacc attcagtatt tgcaggactg
     8701 cgcaacggaa gctgaaattg ctactgagtt cctctacatc gatgatatcg ggttaggtga
     8761 aaaaggtcag ttcacggatt tacaggatca ggtaatttcc aacctgttca agctgtatcc
     8821 gtgggaattt atgttgcgtg agatgttttc caccaagctg gaggatgcag gcgtacgctg
     8881 gctggaaccg gcgtggaaga gcattatctc caacaaggca cttctaccgc tactgtggga
     8941 gatgttcccg aatcacccga acctgctgcc cgcttatttt gcggaagatg atcatccgca
     9001 aatagaaaaa tatgtggtta aaccgatctt ctcccgtgaa ggcgcaaacg tgtcgatcat
     9061 tgaaaacggc aaaaccattg aagcagcgga aggtccgtat ggcgaagaag ggatgattgt
     9121 tcagcaattc cacccgttac cgaaattcgg cgacagctat atgctgattg gtagctggct
     9181 ggtgaacgat caacccgccg gaattggcat tcgtgaagac cgtgcattga tcacccagga
     9241 tatgtctcgg ttttatccac atatttttgt tgagtaatca atgatgccgg atggcattcg
     9301 ccatccggta attgttaacc tatctgcacc gacagcatac tcaggctgcc catttctata
     9361 ccatcgaccg gaatggtaat tggctcctgc ccatcccacg cacctaagac atacaacaac
     9421 ggcagatagt gctccggcgt tgggttcgat aacgcgccac cttcatggtc gaggtaattc
     9481 accagaggat gctgctctac tgccccttgc cacgtcagat tcgctttcac atactcatta
     9541 aacgacatcg cccaaggata tggtgaacta tcaccgtgcc acttcactgt acgcaggtta
     9601 tgcaccacgt tgccactggc gaccaacatt attccttcat ctcgcagcgc tgccagtttg
     9661 cgccccattt cgaaatgcca ggcggcaggt ttgctactgt cgatactcaa ctgcaccatc
     9721 gggatatcgg cgtcaggata catcttaatc agcacgcccc aggaaccgtg gtcaaagccc
     9781 caggcttctt tatccagcgt caccgggacc ggcgctaaca gctcaaccag atgctgtgcc
     9841 agcacaggcg aacccggagc aggataatgc gtatcgtaca gcgcctgcgg gaagccacca
     9901 aagtcatgaa tcgtgggcgg cgtctccatc gcggtcactc ctgttccacg ggtaaaccag
     9961 tgagccgaaa ccaccacaat cgcttgcggg cgtggcaatg tcatccccaa cttctgccag
    10021 ctgcgggtat acaaattatc ttccagcacg ttcatcggac taccgtgacc taaaaacaat
    10081 gctggcatac gtgttgaaga catgatgata tccttaacta aaggtgtcat tttgatatcc
    10141 tcacaatacg cttgttcggc ggagtaagaa cccggataac aatgatgatg atcatcagtt
    10201 attttgacga tctgcctgaa ggtgaagatt tataaggagt tgtcgatgtc agtacctctc
    10261 attctgacca tactggcggg ggcagccacg tttattggcg cgtttctcgg cgttctcggg
    10321 caaaaaccct cgaaccgctt actggcgttt tcgctaggat ttgcggcggg gatcatgttg
    10381 ctcatctcat taatggaaat gcttcctgcc gcactagcag ctgaaggaat gtcgcctgtg
    10441 ttgggttatg gaatgtttat cttcggtctg cttggctatt ttggcctgga ccgcatgttg
    10501 ccacatgcgc atccgcagga tttaatgcaa aaatcggtgc agccgttgcc aaaatcgatc
    10561 aagcgcacag ccattctgct cactctcggc atcagtctgc ataacttccc ggaagggatt
    10621 gccacctttg tcacggcgag cagcaacctg gagctgggat ttggcatcgc actggccgtc
    10681 gctttgcaca atatccctga aggtctggca gtggcaggcc cggtttatgc ggcaacgggg
    10741 tctaaacgca ccgcgattct gtgggcgggg atttctggac tagcagaaat tcttggtggt
    10801 gtgctggcgt ggttaatcct cggtagcatg atttccccgg tggtcatggc ggcaatcatg
    10861 gcggcggttg caggaattat ggtggcgctc tcggttgatg aattaatgcc gctcgccaaa
    10921 gagattgacc ctaataataa ccccagctat ggcgtactat gtggaatgtc agtgatggga
    10981 ttcagtttag tgctgctaca aacggcggga attggttaaa aacaacatca gaagttgtcc
    11041 agcacatgga caacttctgc cagcttcacg aaagccttat tctacctttt cggctgtctc
    11101 ttctctcgta ctgtttaagt atttgttccg cgcttcaagc agtgcgtctc tgtcctggcg
    11161 aaacgcccga caataacgtt tcaaatgcag gaaataaccc accacaacca gagcaatcaa
    11221 tacaatccag taccaggcga taaacatcct tttaccctta atatttaaca atactaaaca
    11281 tttagcgcat aaatttcaca tatccttttt cggatatatt catatggtcg cataataacg
    11341 gaacaattat atgattttga tcataatgaa aaagaatgcc tgatattaat gaaattttct
    11401 catagaaaga gaagcggaat taacatcttg catagcgggg caaaataaaa accgaagcca
    11461 gctacaactt cggtttcttg attaaggcag taattaagca gcggttttca gctggcttta
    11521 cgctcatgtg cctgacggta tgccaccagg tcttcaatag tcacgagcgc catattgtgt
    11581 ttattggcaa actcaatgca ctctggtgca cgcgccatcg tgccatcgtc attagtcagc
    11641 tcacacagca caccagccgg tttaaagcct gccagcgtca tcaaatcaat agtcgcttca
    11701 gtatgaccgc cacgcgtcag tacaccacct gcctgcgcgc gaagtgggaa aacgtggccc
    11761 gggcgattca gatcagaagg ttttgcgcca tcggcaatcg ctgcgcgaac ggtcgtaata
    11821 cgatcagcgg cagaaacacc ggtagtcaca ccttcagccg cttcaatggt cacggtaaaa
    11881 ccggtgccat aggcgctggt gttattttct accatcattg gcagatcaag ttgtttacgg
    11941 cgatcttcag tgatgcacag gcaaacaata ccgctaccgt ggcgaatggt cagcgccatc
    12001 tgctcaacgg tcatggtttc tgccgggaag atcatatcgc cttcgttttc acggtcttca
    12061 tcatcaagca ccattacacc gcgtccttca cgcagcgcag ccagtgcatt ttcaacacgt
    12121 tcgaaaggcg taccaaaaga ggaaagtagc gtctgattca tggtaaaaaa acctcactaa
    12181 aattatggtt accagaatca gggcagtctt aggagtggcg gcatatagcc aaaataacgt
    12241 gagcgggtcc atgcccgaca gaatcgttac tctctcccat ccggactcta accgtcggcc
    12301 ccggaattac accggatctg ctgtcctttg agttcgcacc caaagcgctc gcgggctttc
    12361 aactgagttg atttaccgcc ggtggggaat ttcgccccgc cctgagaata agcggattca
    12421 ctataacgct aatgattagc ggcagcaacg catagcttca cataattctg gtttatgact
    12481 tacccttatc gcactacaat ggtactcaac acctatcagt acagggaaac tacaatgatt
    12541 gacccgaaaa aaattgagca aatcgctcgc caggttcacg aatcaatgcc taaaggaatc
    12601 agggagttcg gggaagatgt ggagaaaaaa atccgccaaa ccctacaagc tcagctgacg
    12661 cgcctcgacc ttgtaagccg tgaagagttc gacgtccaaa cgcaagtcct gttacggact
    12721 cgtgagaaac tggcgctgct tgaacaaaga atgagcgaac tggaaaatcg cagtactgag
    12781 attaaaaagc agccagatcc agagactctc cccccaacgc tgtaaacatt tgtctttaat
    12841 gcactgtaaa ttatgaatta atcctctaat ttacagtgct ttctattacc ttatcgctta
    12901 attccattca gaatatcatc acaaaaatga atgagtgcaa ttgaaaatat aattgttatg
    12961 tattt
//
LOCUS       DAZUDJ010000103        12910 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.103, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000103 DAZUDJ010000000
VERSION     DAZUDJ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12910
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.103"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..555
                     /locus_tag="ACHY1N_004428"
     CDS             <1..555
                     /locus_tag="ACHY1N_004428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415949.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease InsQ/TnpB family
                     protein"
                     /protein_id="HFS4046618.1"
                     /translation="SRKVKFSNNWQKQKRKIQRLHSCIANIRRDYLHKVTTTVSKNHA
                     MIVIEDLKVSNMSKSAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLEYKQLWSGG
                     QVLAVPPAYTSQRCACCGHTAKENRLSQSKFRCQVCGYTANADVNGARNILAAGHAVL
                     ACGGMVQSGRPLKQEPTEMIQATA"
     gene            complement(595..1809)
                     /gene="ydcO"
                     /locus_tag="ACHY1N_004429"
     CDS             complement(595..1809)
                     /gene="ydcO"
                     /locus_tag="ACHY1N_004429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BenE family transporter YdcO"
                     /protein_id="HFS4046619.1"
                     /translation="MLRCLYAITHEVTMRLFSVPPPTLLAGFLAVLIGYASSAAIIWQ
                     AAIVAGATTAQISGWMTALGLAMGVSTLTLTLWYRVPVLTAWSTPGAALLVTGLQGLT
                     LNEAIGVFIFTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQ
                     FTLCGSMLLVWLATKAVAPRYAVIAAMIIGIVIVIAQGDVVTTDVVFKPVLPTYITPD
                     FSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSTPVSPLIVFTGLLALVFSPFGVY
                     SVGIAAITAAICQSPEAHPDKDQRWLAAAGAGIFYLLAGLFGSAITGMMAALPVSWIQ
                     MLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLVGIGSAFWGLIAGGVCY
                     VVLNLIADRNRY"
     gene            1862..2398
                     /gene="sutR"
                     /locus_tag="ACHY1N_004430"
     CDS             1862..2398
                     /gene="sutR"
                     /locus_tag="ACHY1N_004430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SutR"
                     /protein_id="HFS4046620.1"
                     /translation="MENLARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNE
                     SSPTVATLWKIATGLNVPFSTFISPPQPATPSVYDPQQHAMVITSLFPYDPQLCFEHF
                     SIQMAPGAISESTPHEKGVIEHVVVIDGQLDLCVDGEWQTLNCGEGVRFAADVTHIYR
                     NGGEQTVHFHSLIHYPRS"
     gene            2471..4432
                     /gene="rlhA"
                     /locus_tag="ACHY1N_004431"
     CDS             2471..4432
                     /gene="rlhA"
                     /locus_tag="ACHY1N_004431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA 5-hydroxycytidine C2501 synthase"
                     /protein_id="HFS4046621.1"
                     /translation="MTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLKDIAELVPFAHRYGAKIFVTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNLDQIRAIHQATDATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLTRAS
                     SGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVLKVAKDHLDV
                     AVTEPLANGDGLNVMIKREVIGFRANTVEKTRENQYRVWPNEMPADLHKIRPHHPLNR
                     NLDHNWQQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSITHTLDGQFDEANNA
                     EKAMNNLKDGLAKLGQTLYYARDVQINLPGALFVPNSLLNQFRREAADMLDAARLASY
                     QRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRYGVQLIDAAYEAHEEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPLPGSVVASVSPDELLKTLPKRKG"
     gene            complement(4524..4754)
                     /gene="yncJ"
                     /locus_tag="ACHY1N_004432"
     CDS             complement(4524..4754)
                     /gene="yncJ"
                     /locus_tag="ACHY1N_004432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncJ family protein"
                     /protein_id="HFS4046622.1"
                     /translation="MFTKALSVVLLTCALFSGQLMAGHKGHEFVWVKNVDHQLRHEAD
                     SDELRAVAEESAEGLREHFYWQKSRKPEAGQR"
     gene            4976..5130
                     /locus_tag="ACHY1N_004433"
                     /pseudo
     CDS             4976..5130
                     /locus_tag="ACHY1N_004433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415954.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="mRNA interferase"
     gene            5176..5592
                     /gene="hicB"
                     /locus_tag="ACHY1N_004434"
     CDS             5176..5592
                     /gene="hicB"
                     /locus_tag="ACHY1N_004434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HicB"
                     /protein_id="HFS4046623.1"
                     /translation="MRYPVTLTPAPEGGYMVSFVDIPEALTQGETVAEAMEAAKDALL
                     TAFDFYFEDNELIPLPSPLNSHDHFIEVPLSVASKVLLLNAFLQSEITQQELARRIGK
                     PKQEITRLFNLHHATKIDAVQLAAKALGKELSLVMV"
     gene            5671..7077
                     /gene="ydcR"
                     /locus_tag="ACHY1N_004435"
     CDS             5671..7077
                     /gene="ydcR"
                     /locus_tag="ACHY1N_004435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFS4046624.1"
                     /translation="MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVS
                     HAYQLLESLGYIIARPQSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRD
                     PSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
                     QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSV
                     ATDVKEGIDLQALELALQDYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTL
                     IEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKI
                     HHNDSGYFLWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWG
                     EREEQAVKQLGKLIQERL"
     gene            7322..8467
                     /gene="ydcS"
                     /locus_tag="ACHY1N_004436"
     CDS             7322..8467
                     /gene="ydcS"
                     /locus_tag="ACHY1N_004436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter substrate-binding
                     protein YdcS"
                     /protein_id="HFS4046625.1"
                     /translation="MSKTFARSSLCALSMTIMTAHAAEPPTNLDKPEGRLDIIAWPGY
                     IERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMVSLMTKGGYDLVTASGDASLRLI
                     MGKRVQPINTALIPNWKTLDPRVVKGDWFNVGGKVYGTPYQWGPNLLMYNTKTFPTPP
                     DSWQVVFVEQNLPDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQY
                     QAVLKVLRAQHSLIHRYWHDTTVQMSDFKNEGVVASSAWPYQANALKAEGQPVATVFP
                     KEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFGSLPVVPEGCKASPL
                     LGEKGCETNGFNYFDKIAFWKTPIAEGGKFVPYSRWTQDYIAIMGGR"
     gene            8485..9498
                     /gene="ydcT"
                     /locus_tag="ACHY1N_004437"
     CDS             8485..9498
                     /gene="ydcT"
                     /locus_tag="ACHY1N_004437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4046626.1"
                     /translation="MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKT
                     TCLRLIAGFEQLSGGAISIFGKPASNLPPWERDVNTVFQDYALFPHMSILDNVAYGLM
                     VKGVNKKQRHAMAQEALEKVALGFVHQRKPSQLSGGQRQRVAIARALVNEPRVLLLDE
                     PLGALDLKLREQMQLELKKLQQSLGITFIFVTHDQGEALSMSDRVAVFNNGRIEQVDS
                     PRDLYMRPRTPFVAGFVGTSNVFDGLMAEKLCGMTGSFALRPEHIRLNTPGELQANGT
                     IQAVQYQGAATRFELKLNGGEKLLVSQANMTGEELPATLTPGQQVMVSWSRDVMVPLV
                     EER"
     gene            9499..10440
                     /gene="ydcU"
                     /locus_tag="ACHY1N_004438"
     CDS             9499..10440
                     /gene="ydcU"
                     /locus_tag="ACHY1N_004438"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4046627.1"
                     /translation="MAMNVLQSPSRPGLGKVSGFFWRNPGLGLFLLLLGPLMWFGIVY
                     FGSLLTLLWQGFYTFDDFTMSVTPELTLANIRALFNPANYDIILRTLTMAVAVTIASA
                     ILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHL
                     GLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQAS
                     ADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQ
                     QGAIGNMPMAAAFTLVPIVLIALYLAFVKRLGAFDAL"
     gene            10430..11224
                     /gene="ydcV"
                     /locus_tag="ACHY1N_004439"
     CDS             10430..11224
                     /gene="ydcV"
                     /locus_tag="ACHY1N_004439"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4046628.1"
                     /translation="MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPP
                     QGLTLRWFSVAAQRSDILDAVTLSLKVAALATLMALVLGTLATAALWRRDFFGKNAIS
                     LLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
                     WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTL
                     PLWLLNQLGRPRDVPVTNVVALLVMLVTTLPILGAWWLTREGDNGQ"
     gene            11246..12670
                     /gene="patD"
                     /locus_tag="ACHY1N_004440"
     CDS             11246..12670
                     /gene="patD"
                     /locus_tag="ACHY1N_004440"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019145 - aminobutyraldehyde dehydrogenase
                     (NAD+) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0009447 - putrescine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HFS4046629.1"
                     /translation="MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAA
                     VRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIP
                     AIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLA
                     PALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVR
                     MVSLTGSIATGEHIISHTASSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNA
                     GQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVSKA
                     VEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNE
                     EQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLS
                     GYGKDMSLYGLEDYTVVRHVMVKH"
BASE COUNT         3152 a         3159 c         3459 g         3140 t
ORIGIN      
        1 agccgcaagg tcaaattcag caacaactgg cagaagcaga aacgcaaaat acagcgactg
       61 cattcctgta tcgcaaatat ccgcagggac taccttcaca aagtcacaac gaccgtcagc
      121 aaaaaccacg caatgatagt cattgaggat ttgaaggtca gcaacatgtc aaagtcagca
      181 gcgggtacgg tcagccagcc ggggcgcaat gtccgggcaa aatcaggttt aaaccgttcg
      241 atactggatc agggctggta tgaaatgcgc cgccagcttg aatacaagca gctctggagt
      301 ggcggtcagg tgcttgctgt tccgccagcg tatacaagcc agcgttgcgc gtgctgtggt
      361 catacagcga aagaaaatcg tctgtcacaa agtaaattca gatgccaggt atgtggatat
      421 acagcgaacg ccgatgtaaa cggcgctcgt aacattttag cggcggggca cgccgttctt
      481 gcctgtggag ggatggtgca gtcaggccgc ccgttgaagc aggaacccac cgaaatgatt
      541 caggcgacag cctgaacgta gcagggatcc acgtccttca gggcgtggag gatgtcaata
      601 tcggtttctg tcagcgatta aattcaacac cacgtaacaa acgcctccgg caattaatcc
      661 ccagaacgca gaaccaatcc cgaccagcgt caatccactt gccgttacca gaaatgccac
      721 caccgccgcg tcgcgctcac gctcattatg cagcgcctga tacaaactgc cgccaatggt
      781 actcaacagc gccagacctg ccagcatctg gatccaactt acgggcaggg cagccatcat
      841 cccggtaatg gcactaccaa acagacctgc gagcaaatag aaaatgcctg caccggcagc
      901 tgccagccaa cgttgatctt tatccggatg cgcttccggg ctttggcaaa tagccgcggt
      961 gattgccgca ataccgacgg aataaacgcc gaaaggggaa aaaaccagtg ccagcaatcc
     1021 agtaaataca attaatggcg aaacaggagt tgaatatccg gctgctttca ttgctgcgat
     1081 acccggtgcg ttttgcgatg ccatcgtcac cagaaaaagg gggagtgcaa cgctcaggct
     1141 gtgagcaaac gaaaaatcag gggtaatata agtggggaga acgggtttaa agacaacatc
     1201 agttgtgaca acgtcacctt gcgcgataac gatcacgatc ccaataatca tcgcggcaat
     1261 taccgcatag cgcggcgcaa cggccttggt tgccagccat accagcaaca tacttccaca
     1321 caacgtaaat tgaccgtcca gactggcaaa cgcctgtaaa ccaaagcgta ataaaatccc
     1381 ggcaagcatt gccgccgcaa gcgagtgcgg aataatgcgc atcagacgag caaagagtcc
     1441 cgttatgccg cagaggacta ttaacgcgtt ggtgaaaata aaaacgccga tggcttcgtt
     1501 aagtgttagt ccctgcaatc cggtgaccaa caaagccgcg ccaggcgttg accatgcggt
     1561 gagaacaggt acgcgatacc ataatgtcag agtcagcgta ctgacgccca ttgccagccc
     1621 cagcgccgtc atccagccag agatttgtgc agtggtggct ccggcgacaa tcgctgcttg
     1681 ccagattatt gccgctgaac tggcgtagcc aattaatacc gccagaaacc ccgccagtag
     1741 cgtgggtgga ggaacagaaa acagacgcat agtcacctcg tgcgttatag cgtacaggca
     1801 ccgtagcatt tgtccgttat aacgcacaag tgataaactt ccgttttgcc ggaggagtcg
     1861 catggaaaat ctcgctcgct ttttatccac cacacttaaa caactacgcc agcagcgcgg
     1921 ctggagtctt tcgcgactgg cagaagcgac gggcgtttct aaagcaatgt tagggcagat
     1981 tgagcgtaat gagtccagtc cgacggtcgc gacattatgg aaaattgcca ccgggttgaa
     2041 cgtaccattt tcaacattta tttctccgcc gcagcccgct acgccttcag tttatgatcc
     2101 acaacagcac gcgatggtga tcacttcgct gtttccttat gatccacaac tctgctttga
     2161 acacttctcg attcagatgg cacccggtgc aataagcgaa tcgacgcccc atgagaaggg
     2221 ggtaatcgaa catgtcgtcg tcattgatgg acaacttgat ctgtgcgttg atggggaatg
     2281 gcagaccctt aattgtgggg aaggcgttcg atttgctgca gacgtcacgc atatctatcg
     2341 taatggtggg gagcaaaccg tacattttca ttccctcatc cattacccgc gcagttaagc
     2401 gggaaaacta tttcgcaacg tcgcgcttgt ggctaaaata gccgccattt ttcagctact
     2461 ggataagaat gtgaccgtat cttctcatcg acttgaactg ttaagcccgg cacgcgatgc
     2521 cgccattgcc cgcgaagcta ttttgcacgg tgccgatgct gtttatatcg gcggccctgg
     2581 ttttggtgcc cgtcataatg ccagtaatag cctgaaagat attgccgagc tggtgccgtt
     2641 tgcccatcgt tatggtgcaa aaattttcgt cacgcttaac accattttgc atgatgatga
     2701 gctggaaccc gcgcaacggc tgattactga cctctaccag accggtgtcg atgcgctgat
     2761 tgttcaggat atggggattc tggaacttga tattccgccg attgaactgc acgccagtac
     2821 gcagtgcgac attcgtacag ttgaaaaagc gaagttcctc tctgatgttg gcttcacgca
     2881 gattgtgctg gcgcgagagc tgaatcttga tcagatccgc gcgattcacc aggctacgga
     2941 cgcgaccatt gaattcttta ttcatggggc actgtgcgtg gcctattcgg gtcagtgcta
     3001 catttctcat gcgcaaacag ggcgtagcgc caaccgtggc gattgctcgc aggcgtgccg
     3061 tttgccatac acattgaaag acgatcaggg gcgggtggtt tcctatgaaa aacatctgct
     3121 gtcgatgaaa gataacgatc agacagccaa cctcggcgcg ctgattgatg ctggcgtacg
     3181 ctccttcaag attgaagggc gttacaaaga tatgagctac gtgaagaata tcaccgccca
     3241 ttatcgccag atgctggatg ccattattga agaacgtggc gatctgacgc gtgcttcatc
     3301 aggtcgtact gaacatttct ttgttccatc gacggaaaag actttccacc gtggtagcac
     3361 agattatttt gtgaatgccc gtaaaggcga tattggcgcg ttcgattcgc cgaaatttat
     3421 cggcctgccg gtgggtgaag tattgaaagt ggcgaaagat catctcgatg ttgccgtcac
     3481 cgagccactg gcaaatggtg atggcctgaa cgtgatgatt aaacgtgaag tcatcggttt
     3541 tcgtgccaat acggtcgaga aaaccagaga aaatcagtac cgcgtctggc ccaatgaaat
     3601 gccagcagat ttgcacaaaa ttcgtccaca tcacccacta aaccgtaatc ttgatcataa
     3661 ctggcagcag gcactgacaa aaacctccag cgaacgtcgg gtggcggtag acattgaact
     3721 gggcggctgg caggaacaac tgattctgac cctcaccagt gaagagggtg tcagcatcac
     3781 gcatacgctg gacgggcagt tcgacgaagc caataacgcc gaaaaagcaa tgaacaatct
     3841 gaaggatggt ctggcaaaac tggggcaaac cctctattac gcccgcgatg tgcaaattaa
     3901 tttgccgggg gcgctgtttg taccaaacag tctgttaaac cagttccgcc gtgaagctgc
     3961 tgacatgctg gatgctgcgc gtcttgccag ttaccagcgc ggcagccgta aaccggttgc
     4021 tgatcctgcg ccggtttatc cgcaaacgca tctgagtttc ctcgcgaacg tatacaacca
     4081 gaaagcgcgt gaattttatc atcgctatgg tgtgcagctg attgacgcgg cgtatgaagc
     4141 acatgaagag aagggcgaag tcccggtgat gatcaccaag cattgtctgc gctttgcctt
     4201 taatctgtgc ccgaaacagg cgaaaggcaa tatcaaaagc tggaaggcga cgccaatgca
     4261 actggttaac ggcgatgaag tattaacgct aaagtttgat tgccgcccat gcgagatgca
     4321 cgtcattggc aaaatcaaaa atcacatact gaaaatgccg ttaccgggaa gcgtagtggc
     4381 atccgtaagt ccggatgagc tgctgaaaac attgcctaag cgaaaagggt aaaacgccag
     4441 ttttctggtt actcacaact cattgaatct gcatgatatt gcctgccggg taaggcgtct
     4501 cgccgcatcc ggcaacaaat gactcaacgt tgtcccgctt ctggtttgcg cgatttttgc
     4561 cagtaaaaat gctcgcgcaa accttccgcc gactcttccg ccacagcacg caattcatcg
     4621 ctgtccgctt catgacgcag ctgatgatcc acattcttta cccacacaaa ttcatgtcct
     4681 ttgtgccctg ccatgagttg tcctgagaac agcgcacacg ttaataagac aaccgataac
     4741 gccttcgtaa acatcctgcc acctttttct taccttttgc cgctatgatg ccgatcgttt
     4801 cttgaggtta ttattcagtt ttgcaaatta gcgcaaagaa attctggaat cttccttcct
     4861 gattttgcat tgcattctgc cgttgcggcg atttagtgct attttcgagc aaattacaca
     4921 cagaggtaaa cactaatgtt tactttgttg atatactcag cggcagggag gcgatgtgaa
     4981 acaaagcgag ttcagacgtt ggctcgaatc tcagggcgtc gatgtagcga atggccgcaa
     5041 ccatttgaaa ctcaggtttc atgggaggcg cagtgtcatg ccgcgtcact cctgcgtaaa
     5101 gcaatcctga aacaactcgg tttgagttaa tcgccaatta aaaaggttaa tgacatgcga
     5161 gagacagtcg aaattatgcg ttatcccgtc actcttacac ccgcgccgga aggcggttat
     5221 atggtttctt ttgtggatat ccctgaagcg ttgacgcagg gcgaaactgt cgctgaagcg
     5281 atggaagcgg caaaagatgc tttactgacc gcatttgatt tttattttga agataacgag
     5341 cttatcccgt taccttcgcc attaaatagt catgatcact ttattgaagt acctttgagc
     5401 gtcgcctcta aagtattgct gttaaatgct tttttacagt cagaaatcac tcagcaagag
     5461 ttagccaggc gaattggcaa acctaaacag gagattactc gcctatttaa cttgcaccat
     5521 gcgacaaaaa tcgacgccgt ccagcttgcg gcaaaggcgc ttggcaaaga gttatcgctg
     5581 gtgatggttt aattacagtt aacgaaaagt tgtcattttt aacaactgat atagactgcc
     5641 gaatcatctg cacataatta cgattcgata atgaaaaaat accagcagct tgcagaacaa
     5701 ttacgcgagc agattgcgtc gggtatctgg caacccggcg atcgtttgcc ttcgttgcgt
     5761 gaccaggtgg cgctttctgg catgagcttt atgactgtca gccatgccta tcagttgctc
     5821 gaaagtctgg gatatattat cgcgcgaccg cagtcgggtt attacgttgc gccacaggca
     5881 ataaaaatgc cgaaagcgcc agtcattcca gtcactcgag atgaagcagt cgatatcaac
     5941 acttatattt ttgatatgtt gcaggccagt cgcgatccgt cggtcgttcc gtttgcctcg
     6001 gcctttcccg acccgcgact tttccccctc caacaactaa accgctcgct ggcgcaggta
     6061 agcaaaaccg ccacagcgat gagcgtgatt gaaaacttac cgccaggaaa cgcagaactg
     6121 cgtcaggcta ttgctcgtcg ctatgcctta cagggcatca ccatttctcc tgatgaaatt
     6181 gtcattactg ccggggcgtt agaggcatta aacctcagtt tgcaagcggt aactgaaccg
     6241 ggcgattggg tgatagtaga gaatccttgt ttctacggtg cgttgcaggc gctggagcgg
     6301 ctacggctga aggcgttatc ggtggcgacg gatgttaaag aagggatcga tcttcaggcg
     6361 ctggaactgg cgttgcagga ttatccggtg aaagcgtgct ggctgatgac taatagccag
     6421 aacccactcg gatttacctt aacgccgcaa aaaaaagcac aactggtggc gttactcaat
     6481 cagtacaacg taacgctgat tgaagatgac gtttacagcg aactttattt tggacgggaa
     6541 aaaccgctgc ctgcgaaagc gtgggatcgc cacgatggcg ttttgcattg ctcttcgttt
     6601 tcgaaatgtc tggtgcctgg ttttcgtatt ggttgggtcg ccgccggaaa acatgcacgt
     6661 aaaattcaac gcttgcagtt gatgagtacg ctttccacca gctcaccgat gcaacttgcg
     6721 ctggtggatt acctttccac gcgccgatac gacgcccatc ttcgtcgcct gcgtcgccag
     6781 cttgcggaac gtaaacaacg tgcctggcag gcactgctgc gttatctgcc tgcggaagtg
     6841 aaaattcatc ataatgacag tggttacttt ctctggctgg agctccccga gccgttagat
     6901 gccggcgaat taagcctggc ggcactgacg catcatatca gtattgcgcc gggtaaaatg
     6961 ttttctaccg gtgaaaactg gtcacgtttt ttccgtttta ataccgcgtg gcagtgggga
     7021 gagcgtgaag aacaggcggt aaaacaatta ggcaaactta ttcaagaacg gctgtaatag
     7081 cgtttaattt aattcctctt agattgggta atatgaattt cgaatagcag tcatatttcc
     7141 taactccttg actatactcc agaagataac cttacagacg gcataatgcg cggtagctca
     7201 caacctgatt aaattttctc aggggcgaag gtgtgcctgc aagccgccgt ctatggttaa
     7261 acaaggagat atttttacgg cacggcggct gaacaattaa ttacgacagg agtaagacct
     7321 tatgagcaag acatttgccc gcagcagcct gtgtgcgctc agcatgacaa taatgaccgc
     7381 tcacgccgcc gaaccgccta ccaatttaga taaaccggaa gggcgactgg atattatcgc
     7441 ctggccggga tacatcgaac gcggacaaac tgataaacaa tacgactggg taacgcagtt
     7501 cgaaaaagag acaggctgcg cggtgaatgt gaaaaccgcc gcgacttccg atgaaatggt
     7561 cagtctgatg accaaagggg gttacgatct ggttacggca tccggcgatg cctcgctgcg
     7621 tttgattatg ggtaaacgcg tgcagccgat taataccgca ttgattccca actggaaaac
     7681 gctcgatccg cgcgtggtta aaggcgactg gtttaatgtt ggcggcaaag tttacggcac
     7741 accttaccaa tgggggccga acctgctgat gtacaacact aaaaccttcc cgacgccgcc
     7801 ggatagctgg caagtggttt ttgttgagca aaatctgccg gacggcaaga gcaataaagg
     7861 ccgcgttcag gcttatgatg gccctatcta cattgcggac gctgcgttgt tcgttaaagc
     7921 cactcagccg cagttgggca tcagcgatcc gtatcaactc accgaagaac agtaccaggc
     7981 ggtgctgaaa gtgctgcgcg ctcaacacag tttgatccat cgctactggc atgacactac
     8041 cgtgcaaatg agcgatttca aaaacgaggg tgtggttgct tccagtgcct ggccctatca
     8101 ggccaacgcc ctgaaagccg aaggccagcc tgttgctacc gttttcccga aggagggtgt
     8161 taccggttgg gctgatacca ccatgctgca tagcgaagcg aaacatccgg tttgcgccta
     8221 caaatggatg aactggtcat taacgccaaa agtgcagggc gatgtggcgg cctggtttgg
     8281 ctcgttaccg gtagtgccgg aagggtgtaa agccagtccg ttattaggcg aaaaaggttg
     8341 tgaaaccaac ggttttaact atttcgacaa aatcgccttc tggaaaacgc ctatagcaga
     8401 agggggcaag tttgttccct acagtcgctg gacgcaggat tacattgcca ttatgggcgg
     8461 tcgctaactt cgctggggtg ctttatgacg tacgcagtgg agtttgacaa cgtctcgcgg
     8521 ttgtacggtg acgtgcgcgc agtagatggc gtcagtattg cgataaaaga tggtgagttc
     8581 ttctctatgc tggggccgtc cggctccggc aaaaccacct gcctgcgcct gattgctggc
     8641 ttcgaacagc tttccggcgg ggctatctct atctttggta aacccgccag caatctgcca
     8701 ccgtgggagc gggacgtgaa tactgtcttt caggactacg cgctatttcc gcatatgtcg
     8761 attcttgaca atgtcgccta tgggctgatg gtcaaaggcg tgaataaaaa gcagcggcac
     8821 gcaatggcgc aagaggcgct ggagaaagtg gcgttggggt ttgtacatca acgtaaaccg
     8881 tcacaacttt ctggtggtca gcgccagcgg gttgctatcg ccagagcatt ggtgaatgaa
     8941 ccgcgcgtat tgctgttgga tgaaccgctc ggcgcactgg atctcaaatt gcgtgagcag
     9001 atgcagctgg aactgaaaaa actgcaacag tctctcggta tcacttttat cttcgttacc
     9061 cacgatcagg gcgaagcgtt atcgatgtcc gatcgtgtgg cggttttcaa taatggacgc
     9121 attgagcagg tcgattcccc gcgcgatctc tatatgcgcc cgcgcacgcc gtttgttgcc
     9181 ggattcgtcg ggacatccaa cgtttttgat ggactgatgg cagagaaact ttgtggcatg
     9241 acgggaagct tcgccctgcg accggaacat atccgcctca acacccctgg tgaactgcag
     9301 gccaatggca cgatccaggc ggtgcaatat cagggcgcgg caactcgttt tgaactgaaa
     9361 ttgaacggcg gtgaaaaact gcttgtgagt caggccaata tgacaggcga agaactgcct
     9421 gccacgctca cgcccggaca acaggtgatg gtttcctggt cgcgtgatgt gatggtgccg
     9481 ctggttgagg agaggtgaat ggcgatgaat gtattgcaat caccttcacg tccaggtctg
     9541 ggtaaggtgt ccggtttctt ctggcgtaat ccggggctgg ggctgttttt actgctgctt
     9601 ggcccgctaa tgtggtttgg cattgtctat ttcggctcgc tgctgacact gttatggcag
     9661 ggattttata cttttgacga tttcaccatg tcggtaacgc cggaactgac gctggcgaat
     9721 atccgtgcgc tgtttaatcc ggcgaattac gacatcattc tccgcacgct gactatggct
     9781 gtggcagtca ctatcgccag cgccattctg gcttttccaa tggcgtggta tatggcgcgc
     9841 tataccagcg ggaaaatgaa agcttttttt tatattgcgg taatgttgcc gatgtgggcg
     9901 agctacattg ttaaagccta tgcctggacg ttattgctgg caaaagatgg cgtggctcag
     9961 tggtttttac aacatcttgg gctggaacca ctgctgacgg cgttccttac attacctgcg
    10021 gtgggcggaa atacgctgtc aacttccggg ctggggcgct ttctggtgtt tctctatatc
    10081 tggttgccgt tcatgatcct gcccgttcag gcggcgcttg agcgtttgcc gccgtcattg
    10141 ttgcaggcgt cggctgatct cggcgcacgt ccacgacaaa cctttcgcta tgtggtgctg
    10201 ccgctggcaa tcccgggtat tgccgctggc tctatcttta ccttctcact cacactgggc
    10261 gattttatcg tcccgcagct ggttggtcct ccaggatatt ttatcggcaa tatggtttat
    10321 tcccagcagg gggcgattgg caatatgccg atggcggcgg cattcaccct ggtgccgatt
    10381 gttctcatcg cactgtacct ggcgttcgtg aaacgtctgg gagcgttcga tgcactctga
    10441 acgcgcaccg tttttcctca aactggcggc ctggggcggc gtggttttcc tacattttcc
    10501 catcctgatt atcgccgctt atgcgtttaa cactgaagat gcggcgttta gttttccacc
    10561 gcagggcctg acgctgcgct ggtttagcgt ggcagcacag cgtagtgata ttcttgatgc
    10621 cgtgacactg tcacttaaag tggcggcgct ggcgacatta atggcgctgg tgttagggac
    10681 gctggcaact gccgcgctgt ggcgacgaga ctttttcggc aaaaacgcca tttcgctgtt
    10741 actgctgctg cccattgcgc tgccgggcat tgtcactggt ctggcgctat taaccgcttt
    10801 taaaaccatc aatctggagc cgggattttt caccatcgtg gtcggtcatg cgactttttg
    10861 cgtagtggtg gtgtttaaca atgtcatcgc ccgttttcgc cgcacctcgt ggagtctggt
    10921 tgaggcgtca atggatcttg gggccaatgg ctggcaaacc ttccgctacg tagtgttgcc
    10981 gaatctcagt tcggcgctac tggcaggagg aatgctggcg tttgccttgt cgttcgatga
    11041 aatcatcgtt acgactttta cggcaggtca tgaacgaacg ttaccgttgt ggttgctcaa
    11101 tcagcttggg cgaccgcgtg atgtaccggt aactaacgtg gtggcactgc tggttatgtt
    11161 ggtaacaacc ttgccgatcc tgggggcctg gtggctaacc cgcgaaggcg acaatggtca
    11221 ataaccactg atacaggaat atgctatgca acataagtta ctgattaacg gagaactggt
    11281 tagcggcgaa ggggaaaaac agcctgtcta taatccggca acgggggacg ttttactgga
    11341 gattgccgag gcatccgcag agcaggtcga tgctgctgtg cgcgcggcag atgcagcatt
    11401 tgccgaatgg gggcaaacca cgccgaaagt gcgtgcggaa tgtctgctga aactggctga
    11461 tgttatcgaa gaaaatggtc aggtttttgc cgaactggag tcccgtaatt gtggcaaacc
    11521 gctgcatagt gcgttcaatg atgaaatccc ggcgattgtc gatgtttttc gctttttcgc
    11581 gggtgcggcg cgctgtctga atggtctggc ggcaggtgaa tatcttgaag gtcatacttc
    11641 gatgatccgt cgcgatccgt tgggggtcgt ggcttctatc gcaccgtgga attatccgct
    11701 gatgatggca gcgtggaaac tggctccggc gctggcggca gggaactgcg tagtgcttaa
    11761 accatcagaa attaccccgc tgaccgcgtt gaagttggca gagctggcga aagatatctt
    11821 cccggcaggc gtgattaacg tactgtttgg cagaggcaaa acggtgggtg atccgctgac
    11881 cggtcatccc aaagtgcgga tggtgtcgct gacgggctct atcgccaccg gcgagcacat
    11941 catcagccat accgcgtcgt ccattaagcg tactcatatg gaacttggtg gcaaagcgcc
    12001 agtgattgtt tttgatgatg cggatattga agcagtggtc gaaggtgtac gtacatttgg
    12061 ctattacaat gctggacagg attgtactgc ggcttgtcgg atctacgcgc aaaaaggcat
    12121 ttacgatacg ctggtggaaa aactgggtgc tgcggtggca acgttaaaat ctggtgcgcc
    12181 ggatgacgag tctacggagc ttggaccttt aagctcgctg gcgcatctcg aacgcgtcag
    12241 caaggcagta gaagaggcga aagcgacagg gcacatcaaa gtgatcactg gcggtgaaaa
    12301 gcgcaagggt aatggctatt actatgcgcc gacgctgctg gctggcgcat tacaggacga
    12361 tgccatcgtg caaaaagagg tatttggtcc agtagtgagt gttacgccct tcgacaacga
    12421 agaacaggtg gtgaactggg cgaatgacag ccagtacgga cttgcatctt cggtatggac
    12481 gaaagatgtg ggcagggcgc atcgcgtcag cgcacggctg caatatggtt gtacctgggt
    12541 caatacccat ttcatgctgg taagtgaaat gccgcacggt gggcagaaac tttctggtta
    12601 cggcaaggat atgtcacttt atgggctgga ggattacacc gtcgtccgcc acgtcatggt
    12661 taaacattaa gttagatgtt agtggctgtt ataggacggc cactatcgtt ttaggttctg
    12721 agtttaatgg cggttaagta ttagaatgat tacattaata actagcgtaa aaattaggct
    12781 aaatgtttga tggcgatttt tcatcctgtc acagttgatt agcataaggc tttagagtat
    12841 cgttattaaa ctaataattt ataagtagaa gtattaacaa tgaaagttca attgtacaaa
    12901 ttcacggaag
//
LOCUS       DAZUDJ010000104        12712 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.104, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000104 DAZUDJ010000000
VERSION     DAZUDJ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12712
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.104"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            61..570
                     /gene="tssB"
                     /locus_tag="ACHY1N_004441"
     CDS             61..570
                     /gene="tssB"
                     /locus_tag="ACHY1N_004441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001369054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HFS4046630.1"
                     /translation="MADSFQNEVPAARVNIKLDLHTGNAKKKVELPLKLLAVGDYSNG
                     KEQRPLSERDKIDINKNNFNSVMAEFSPAVNLTVEDTLSGSGNEQNIALEFKSLKDFE
                     PEQVAKNIPQLRVLLAMRNLLRDLKSNLLDNATFRRELENILKDPTLSSELRDELAKL
                     RRRRTFNPK"
     gene            619..2157
                     /gene="tssC"
                     /locus_tag="ACHY1N_004442"
     CDS             619..2157
                     /gene="tssC"
                     /locus_tag="ACHY1N_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HFS4046631.1"
                     /translation="MSVQQEHATSETATLTTTESGGVYQSLFDKINLTPVSSIQEIDL
                     WQNSETLADASPDERVTAAIHVLLSCLAKSGENVVKLDKSLLDFHIDDLDQKISKQLD
                     AVMHHPEFQKVESLWRGTWFVVQRTDFRKNVRIELLDISKEHLRQDFDDSPEIIQSGL
                     YRHTYIQEYDTPGGEPVASLISSYEFDNSPQDIALLRNISRVSAASHMPFIGSVGPKF
                     FLKNSMEEVAAIKDIGNYFDRAEYIKWKSFRDTDDSRYVGLVMPRVLGRLPYGPDTVP
                     VRSFNYVEEVKGPDHEKYLWTNASFAFAANMVKSFVNNGWCVQIRGPQAGGAVADLPI
                     HLYDLGTGNQVKIPSEVMIPETREFEFSNLGFIPLSYYKNRDYACFFSANSAQKPALY
                     DTADATANSRINARLPYIFLLSRIAHYLKIIQRENIGTTKDRRVLELELNTWVRTLVT
                     EMTDPGDELQASHPLRDGKVIVEDIEDNPGFFRVRLFAVPHFQIEGMDINLSLVSQMP
                     KAKA"
     gene            2175..3512
                     /gene="tssK"
                     /locus_tag="ACHY1N_004443"
     CDS             2175..3512
                     /gene="tssK"
                     /locus_tag="ACHY1N_004443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HFS4046632.1"
                     /translation="MKIHRPLWAEGTFLSSQQFQQQARWEAFSNDSIAQLCIRHPWGI
                     ANVLFDRDALMSGKLKTQAVRLRFADGTLIDSDVSDVLPLACDLHALTNDSAVVLLAL
                     PLAHGNGGNLGQGEQTERPLRYRQEWQKVQDIYGSDSEDMAVERHALSLRFAHDNNQD
                     YITCPLARLVRDVQGNWTQDEGYIPPLLAFNAHDGLVQRLDTLLLQLRAKCQRLMAMR
                     RESNQRMADFAVADVSLFWLLNALNSAEPVLSDFLRYPAVHPELVWRELARLAGALLT
                     FSLEHNVSAVPPYVHESPSTVFPPLFSLLSELLEASLPSRVIALDLGSLPGNRWKADL
                     HDPRLREEADFYLSVRSSLPAHQVLHQLPLVCKIGAPDDVTLLINVALNGVPLVPLTS
                     VPAALPLRLENQYFALDMHSDAAKSMLESGCCMIYAPGTMGDLKPELFAVLRT"
     gene            3509..4174
                     /gene="tssL"
                     /locus_tag="ACHY1N_004444"
     CDS             3509..4174
                     /gene="tssL"
                     /locus_tag="ACHY1N_004444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssL, short
                     form"
                     /protein_id="HFS4046633.1"
                     /translation="MKKETDINIDALLRDTFLTVVELRQGTTVRHGMELYRHCQRQVE
                     GVRERLKDAGFSRENVEHITYAQCALLDETVLSRSGMDDGQAIWMKDPLQAHFFNTLQ
                     AGELLYERMKQVLQEPAPAQAVLTCFHRVLLLGFRGRYQDPVAPERDQLISTLNGLVA
                     PFGVLPETAVLNVPLSPRQHPLLHSPFFWLVTLTLLLAGVWWGLHHWLNVLVDELLPQ
                     SLR"
     gene            4187..5839
                     /locus_tag="ACHY1N_004445"
     CDS             4187..5839
                     /locus_tag="ACHY1N_004445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HFS4046634.1"
                     /translation="MRNTLKQAVVLWGMVLLLVLWSVFISPSGVLIWAGAAAIVLTVA
                     ALLIYRRRQAWTEMTGDAGLLSLPPETYRQPVVLVCGDMSAHLFTDSPVRQVSEGLYL
                     HVSDEEQLVAQAERLLTLRPAWASQLAVAYTVMPGMYRDAAVLTGQLRRFAHSMATVR
                     RRAGVNVPWLLWSGLSGSPLPERANSPWFICTGGEIHVATSAETASPAQWLTQTSTQE
                     RSQQLCYLLKAESLMQWLNLNMLAALNGPETKCPPLAMAVGLVPSLPAVDNNLWQLWI
                     TARTGLTTDIADTGTDATLPFPDALLRRLPRQSGFTPLRRACVTMLGITTVAGIAALC
                     LSATENRQLLRHIGDDLHQFYAVPAEEFITKARRLSVLKDDAIMLDGYYREGEPLRLG
                     LGLYPGEQIRQPVLRAIRDWRPPEQKMEVTASLQAQTVRLDSMSLFDVGQARLKDGST
                     KVLVDALVNIRAKPGWLILVAGYTDATGDEKSNQQLSLRRAEAVRNWMLQTSDIPATC
                     FAVQGLGESQPAATNDTPQGRAVNRRVEISLVPRSDACQDVK"
     gene            5897..6388
                     /locus_tag="ACHY1N_004446"
     CDS             5897..6388
                     /locus_tag="ACHY1N_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HFS4046635.1"
                     /translation="MAIPAYLWLKDDGGADIKGSVDVQGREGSIEVVALDHDVYIPTD
                     NNTGKLTGTRTHKPFIFTKEIDASSPYLYKAVTTGQTLKTAEFKFYRINDAGQEVEYF
                     NITLDNVKLVRVAPLMHDIKEPSKEKHNHLERIEFRYEKITWTYKDGNIIHSDSWNER
                     PSA"
     gene            6579..9224
                     /gene="tssH"
                     /locus_tag="ACHY1N_004447"
                     /gene_synonym="clpV"
     CDS             6579..9224
                     /gene="tssH"
                     /locus_tag="ACHY1N_004447"
                     /gene_synonym="clpV"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HFS4046636.1"
                     /translation="MTGNHPAALLRRLNPYCARALDAAASLCQTRAHAEITIEHWLLK
                     LLEQGEGDITVIARRYEWDIDTLWQSLLAHLDTLPRSVRERPQLSEPLTALIRQAWLI
                     ASLEGDDPQIRSQHLLMALTEKPMLPACNDLWVLLSLSRVQLERLRPLLDAQSDECPA
                     RQPQATEPLTSAQPESATTDAPAKTLTGKQDDALLAVLNRFTEDVTEKARSGRIDPVF
                     GRDTEIRQMVDILSRRRKNNPILVGEPGVGKTALVEGLALRITEGNVPDSLKTVHIRT
                     LDLGLLQAGAGVKGEFEQRLKNVIDAVQKSPEPVLLFIDEAHTIIGAGNQAGGADAAN
                     LLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTASLMLRGLKA
                     RYAQHHGVHMLDSAIQTAVRLSRRYLTGRQLPDKAVDLLDTAGARVRMSLDTLPEPLT
                     QLQARLTALDIEREAIEQDSVFYPETSPERLAELTDLRDELQAEAGHLEAQYQQEKRL
                     AQQIMALRQEGADSTDLQQQLRTHQGFAPLLALDVDARAVATVVADWTGIPLSSLLRD
                     EQSDLLSMEQSLENRVVGQSPALCAIAQRLRAAKTGLTPENGPQGVFLLTGPSGTGKT
                     ETALTLADTLFGGEKSLITINLSEYQEPHTVSQLKGSPPGYVGYGQGGVLTEAVRKRP
                     YSVVLLDEVEKAHRDVMNLFYQVFDRGFMRDGEGREIDFRNTVILMTANLGSDHIMQL
                     LEEKPDATDADLHELLYPLLREHFQPALMARFQTVIYRPLGQEAMRAIVEMKLAQVVR
                     RLRQHYGLETEINDSLYDALTAACLLPDTGARNIDSLLNQQILPVLSQQLLAQQAAHR
                     KPAQLRLGWDEEDGIVLEFATEEMQ"
     gene            9236..11743
                     /locus_tag="ACHY1N_004448"
                     /pseudo
     CDS             9236..11743
                     /locus_tag="ACHY1N_004448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512755.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2345 domain-containing protein"
     gene            11765..12358
                     /locus_tag="ACHY1N_004449"
     CDS             11765..12358
                     /locus_tag="ACHY1N_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HFS4046637.1"
                     /translation="MADKSEKKKETTNKSAKKTLTKKSEKLTPAKDTAPKQVNVDPAI
                     RLKQIRQLVRNNNKSIMGEDYIICQIYKESRFKQFAGKNKHNAKGLMQMQRNAVRQVF
                     KYRQQKIKGRMTTDKETNEAFANADTFYKSDKIFDEKENIKIGTEYLQYWIDKEATIE
                     EAYRGTDEAYYSVIKPCAEKLAKDPDNIQILMEGIGR"
     gene            12462..>12712
                     /locus_tag="ACHY1N_004450"
     CDS             12462..>12712
                     /locus_tag="ACHY1N_004450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001378343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046638.1"
                     /translation="MQLLSLRTIDGDTLYLKFRNVITEAFLDTPTKSYDFFGDVVLSQ
                     CINGSLIFALEYGSPYIKGCLVTGWENGFKGKNSPEGFC"
BASE COUNT         3090 a         3372 c         3615 g         2635 t
ORIGIN      
        1 atcccgtgaa tataattatg tcaataacca tcagaaaaag tggatgatga ggaaaaggat
       61 atggccgaca gtttccagaa tgaagttccc gccgctcgtg taaatatcaa gcttgacctg
      121 catacaggca atgctaaaaa gaaagttgaa ctccccctca agcttcttgc tgttggcgat
      181 tacagtaacg gaaaagagca acgtccgctg tccgaacggg acaagattga tatcaataaa
      241 aacaacttca acagtgtcat ggctgagttt tcgcctgcgg ttaatttaac agtagaagac
      301 acactaagcg gaagcggtaa tgagcaaaat atcgcgcttg aatttaaaag cctgaaagat
      361 tttgaacccg aacaggtagc aaaaaatatc ccacagcttc gtgtattact cgctatgcgc
      421 aatttattac gtgacctgaa atccaatctg ctggataacg caacgtttcg ccgtgaactg
      481 gaaaatattc tgaaagaccc aacgctcagt tcagaactgc gtgatgaact ggcgaaattg
      541 cgccgcagga gaacgtttaa cccgaagtga tattcaggtt aaaccggaga agaaaggatc
      601 actgaaaagg aaatgctgat gtctgtacaa caagaacatg ccacctctga aactgcaaca
      661 ctgaccacca ctgagtccgg cggcgtttat cagtccctgt ttgataaaat taatttaacc
      721 ccggtgtctt ccattcagga aatagattta tggcaaaaca gcgaaacact ggcggatgcc
      781 tcacccgatg agcgcgtgac agcggcgatt cacgttctgc tttcctgtct ggcgaaatca
      841 ggcgagaacg tggtcaagct cgacaagagc ctgctggatt ttcatatcga cgatttggat
      901 cagaaaatca gtaagcagct tgatgcggtc atgcaccatc ctgaattcca gaaagtcgag
      961 tcgctgtggc gcggcacatg gttcgtcgta cagcgcactg attttcgcaa aaatgtcaga
     1021 attgaattgc tggatatcag caaagagcat ctgcgtcagg atttcgacga ctccccggaa
     1081 atcattcaga gtggtttata tcgtcataca tatattcagg agtacgatac gccgggtggc
     1141 gaacctgttg cctcattaat ttccagctat gaatttgata acagcccgca ggatattgcc
     1201 ctgctgcgca atatttccag agtgtctgcc gcttcccata tgccttttat cggttctgtc
     1261 gggccgaaat tcttccttaa aaattcgatg gaagaagtcg ccgcgattaa agatatcggc
     1321 aactactttg accgcgcaga atatattaaa tggaaatcgt ttcgtgatac cgatgacagc
     1381 cgctatgtgg gattagtgat gccgcgagtg ctgggccgtc tgccctatgg gccggacacg
     1441 gtgcctgtac gcagctttaa ctatgtggaa gaagtcaaag gcccggatca cgaaaagtat
     1501 ctctggacaa acgcctcgtt cgcctttgcc gccaatatgg tgaagagctt tgtgaataat
     1561 ggctggtgcg tgcagatccg cggtccacaa gcaggtggcg cagtggccga tctgcccatc
     1621 catctttacg atctcggcac cggcaatcag gtcaaaattc cgtccgaagt gatgatcccg
     1681 gaaacccgcg aatttgaatt ttccaacctt ggctttattc cgctctctta ttataagaat
     1741 cgcgattacg cctgcttctt ctcggcaaac tctgcccaga aaccggcgtt gtatgatacc
     1801 gctgacgcca ccgccaacag ccgtattaac gcccgtctgc cctatatctt cctgctgtcc
     1861 cgcattgcgc attacctgaa aatcatccag cgcgagaata tcggtaccac caaagaccgc
     1921 cgcgtactgg aactggaact gaacacctgg gtccgcacac tggtgacgga gatgaccgat
     1981 ccgggtgatg aactgcaggc gtctcacccg ctgcgcgacg gtaaggttat cgtggaagat
     2041 attgaggaca atccgggctt cttccgcgtc agactctttg ccgtgccgca tttccagatt
     2101 gaagggatgg atatcaacct gtcactggtt tcccagatgc cgaaagcgaa agcctgaccg
     2161 ggaagtggtg tgatatgaaa attcatcgac cactgtgggc tgaggggaca ttcctgtcct
     2221 ctcagcagtt tcagcagcag gcccgctggg aagcgttcag caatgacagc attgcgcaac
     2281 tttgtattcg tcatccgtgg gggatcgcga atgtgctctt tgaccgcgat gccctgatgt
     2341 ccggaaagct gaaaacgcag gcagtacgcc tgcgttttgc tgatggcacg ctgatcgatt
     2401 ctgacgtgag cgatgttctg cctctcgcct gcgatctgca cgcgctgacg aacgacagcg
     2461 cggttgttct gctggcgctg ccgcttgccc atggtaacgg cggtaatctc ggtcagggtg
     2521 agcagactga aagaccgcta cgctatcgtc aggaatggca aaaggtacag gatatctacg
     2581 gcagtgacag tgaagatatg gccgttgagc gtcatgcgct gtccctgcgc tttgctcatg
     2641 ataacaatca ggattacatc acctgcccac tggcgcgtct ggtgcgggat gttcagggca
     2701 actggacaca ggatgagggc tatattccgc cgttactggc gtttaatgct catgacgggt
     2761 tggtacagcg tctggacacg ctgctgttgc agctacgggc caaatgtcag cgcctgatgg
     2821 cgatgcgtcg ggaaagcaac cagcgtatgg cggacttcgc cgtcgccgat gtctccctgt
     2881 tctggttgct taacgcgctg aactccgccg agccggtgct gagtgatttc ctgcgctacc
     2941 cggcggttca tcccgaactg gtctggcggg agctggcgag gcttgccgga gcgctgctga
     3001 cgttttccct tgaacataac gtcagcgccg ttccgcccta tgtccacgaa tcgccgtcca
     3061 ctgtctttcc gccactgttc tccctgctca gcgaactgct ggaagcaagc ctgccgtcac
     3121 gggtgatcgc gctggatctg ggatccctgc cgggcaaccg ctggaaagcc gacctgcacg
     3181 atccgcgcct gcgggaagag gccgattttt acctgtccgt tcgttcctca ctgcctgcgc
     3241 atcaggtact gcaccagcta ccgctggtct gcaaaatcgg tgcgcctgat gacgtcacgc
     3301 tgcttatcaa cgtggcgctg aatggtgttc cactggtgcc actgacctca gttccggcag
     3361 cgctgccact gcgcctggag aatcagtatt ttgcgctgga tatgcacagt gacgcggcta
     3421 aatcgatgct ggagtccggg tgctgcatga tttatgcgcc aggaaccatg ggcgacctga
     3481 aacctgaact gtttgcggtg ctgcgcacat gaaaaaagag acggatatca atatcgacgc
     3541 gctgctgcgc gacacgtttc tgacggtggt ggaactgcgt cagggaacca ccgtgcgtca
     3601 cggtatggag ctgtatcgcc actgccagcg gcaggtggag ggggtccgcg aacgcctgaa
     3661 agatgccggg ttcagccggg agaacgtgga gcacattact tacgcacagt gcgccctgct
     3721 ggacgaaaca gtcctgagtc gcagcggcat ggacgacggt caggccatct ggatgaagga
     3781 tccactccag gcgcatttct tcaacaccct gcaggcaggc gagctgctgt acgagcggat
     3841 gaagcaggtg ttgcaggagc ccgcgcctgc acaggcagtg ctgacctgct ttcaccgtgt
     3901 cctgctgctg ggatttcgcg ggcgttatca ggatccggtg gccccggagc gtgaccaact
     3961 tatttcgacg ctcaacgggc tggtcgcgcc atttggcgtg ctgccggaaa cggcggtact
     4021 gaacgtgccg ttatcccccc gtcagcaccc tttgctgcat tcgccgtttt tctggctggt
     4081 aacgctgacg ctgctactgg ccggtgtctg gtggggactg caccactggc tgaacgtgct
     4141 ggtggatgaa ttgctgccgc aaagcctgcg gtaaagggag tcgtgagtga ggaacacgct
     4201 gaaacaggcc gtcgtgctgt ggggaatggt gttactgctg gtgctgtggt cggtgtttat
     4261 cagtccgtct ggcgtactga tatgggccgg ggcggcggct atcgttctga cggttgccgc
     4321 gttgctgatt taccggcgca ggcaggcgtg gacggagatg accggcgatg ccgggttgtt
     4381 atcgctgccg ccggaaacgt accgacaacc ggtagtgctg gtctgtggcg atatgtcggc
     4441 gcatctgttc actgacagcc cggtccggca ggtttcagaa gggctgtatc tgcatgtttc
     4501 tgatgaagaa cagcttgtgg cgcaggcgga gcgattactg acccttcgcc cggcgtgggc
     4561 atcgcagctt gccgtggcat ataccgtcat gcccggcatg taccgggatg cggcggttct
     4621 gaccggacaa ctgcgccggt tcgcccacag tatggcgaca gtgcgtcgcc gggcgggcgt
     4681 aaacgtcccc tggcttctct ggagcgggct gtccggctcg ccgttgccgg agagagcgaa
     4741 ttcaccgtgg tttatctgta ccggcggcga aattcatgta gcgacgtctg ctgaaaccgc
     4801 ctcccccgcg cagtggctca cgcagaccag cacacaggag cgcagccagc aactctgtta
     4861 cctgctgaaa gccgaaagcc tgatgcagtg gctgaatctt aatatgctgg cggcactgaa
     4921 cggcccggaa acgaaatgtc cgccactggc gatggccgtg gggctggtcc cctcgttgcc
     4981 tgcggtggat aacaacctgt ggcagttgtg gatcaccgcc agaaccggcc tgacgacgga
     5041 tatcgcggac accggcacag acgccacgct gccgtttccg gatgccctgt tacggcggtt
     5101 gccgcgtcag tcgggcttta ccccgctgcg acgagcctgc gtgaccatgc tgggcatcac
     5161 caccgtggcg ggtatcgccg cgctgtgtct gtcagccacg gagaatcgcc agttattacg
     5221 gcatatcggt gatgatctgc accagtttta tgccgttccg gcggaggaat ttatcaccaa
     5281 agcccgtcgt ctgtcggtgc tgaaagacga tgcgatcatg ctcgatgggt attaccggga
     5341 aggagagcca ctgcgtctcg gtctggggtt ataccccggt gaacaaatcc gccagccggt
     5401 attacgcgcc attcgtgact ggcgtccgcc tgagcaaaaa atggaagtga cagcctcgct
     5461 tcaggcgcag accgtgcgtc ttgacagtat gtcgctgttt gacgtcggac aggcccgcct
     5521 gaaagacggc tcgacaaaag tgctggtgga cgcactggtg aacatccggg caaaaccggg
     5581 ctggctgatc ctcgtggccg gatataccga cgccaccggc gacgaaaaaa gcaatcagca
     5641 gttatcgctg cgacgtgccg aagcggtgcg caactggatg ctgcagacca gcgacatccc
     5701 ggccacctgt tttgccgtac agggactggg cgagagccag cctgcggcga ccaacgatac
     5761 gccacagggc cgggcagtca accggcgcgt cgaaatcagt cttgttccgc gttctgacgc
     5821 ctgtcaggac gtgaaataaa acataccgcc ggaagaaggc ggtgcttcaa tcacactaac
     5881 aaggagagta attctcatgg ctattcctgc ttatctctgg ctgaaagatg acggcggcgc
     5941 ggatatcaaa ggttccgtgg acgttcaggg gcgcgaaggc agcatcgaag tggtggcgct
     6001 ggatcacgat gtgtacatcc cgaccgacaa caacaccggc aaactgaccg gtactcgcac
     6061 ccataaaccg ttcattttta ccaaagaaat cgatgcgtcc agcccgtatc tctacaaagc
     6121 tgtgaccacc ggtcagaccc tgaaaacggc ggaatttaag ttttaccgca tcaacgacgc
     6181 cggtcaggaa gtggagtact tcaacatcac gctggataac gtcaagctgg tcagagtcgc
     6241 tccgctgatg cacgacatca aggagccttc caaagagaag cataaccacc tggaacgcat
     6301 tgagttccgc tacgaaaaaa tcacctggac ttacaaagac ggcaacatca ttcattccga
     6361 ctcgtggaat gaacgtcctt ccgcctgata actgcggcag acaggaaact gtctgccttt
     6421 ctgttgtgtg ctttgcccag tgccgcaggc accggtactg agcaaagcat acccacaatc
     6481 tggtgatacc tgatgggcct gagtgaggta acggctatgg gcggtagcgt acctgaacgc
     6541 agatcgcagg aatacagaac acgataagga aaccttctat gaccggaaat caccccgccg
     6601 cgctgctgcg tcgccttaac ccgtactgtg cacgggcgct ggacgctgcc gcctcactgt
     6661 gtcagacccg cgcccatgcg gagataacca ttgaacactg gctgctgaaa ctgctggagc
     6721 agggagaagg cgatatcacg gtgattgccc gccgctatga atgggatatc gacacgctct
     6781 ggcagtctct gctggcacat ctggacacct taccccgctc ggtccgcgaa cgtccgcagc
     6841 tttctgaacc cctgacggcg cttatcaggc aggcgtggct gattgcctcg ctggaaggcg
     6901 acgacccgca aatccgcagt cagcacctgc tgatggcgct gacagaaaaa ccgatgctgc
     6961 ccgcctgtaa tgacctgtgg gtattgctga gcctgagccg cgtgcagctt gagcggctgc
     7021 gccccctgct ggatgcgcag tcggatgaat gtccggcacg tcagccacag gccaccgaac
     7081 cgctgacatc cgcgcaacca gagtcggcaa cgacggacgc accggcaaaa acgctgacgg
     7141 ggaaacagga tgacgccctg ctggcggtac ttaaccgctt taccgaagac gtgacggaaa
     7201 aagcccgcag cgggcgaatc gacccggtat tcgggcgcga caccgaaatt cgccagatgg
     7261 tcgatatcct ctcccgtcgc cgcaaaaaca acccgattct ggtgggagaa ccgggcgtgg
     7321 gcaaaaccgc gctggtggaa gggctggcgc tgcgtatcac cgaaggcaac gtgccggaca
     7381 gcctgaaaac ggtgcatatc cgcacactgg acctcggtct gttacaggct ggcgcgggcg
     7441 ttaaaggtga atttgagcag cgactgaaaa acgtgattga tgcagtacag aaatcaccgg
     7501 agccggtact gctgtttatt gatgaagccc ataccattat cggcgcgggt aatcaggcgg
     7561 gcggcgcgga tgcggcgaac ctgctgaaac cggcgctggc aaggggcgag ctgcgcacca
     7621 tcgccgccac aacgtggagc gaatacaaac agtattttga gcgcgacgcc gcgctggaac
     7681 gccgcttcca gatggtgaaa gtcgacgagc cggatgatga caccgccagc ctgatgctgc
     7741 ggggactcaa ggcccgctat gcacagcacc acggcgtaca tatgctggac agcgccattc
     7801 agaccgccgt gcgcctgtcg cgccgctatc tgaccggacg ccagttgccg gacaaggcgg
     7861 ttgatttgct ggataccgcc ggggcaagag tccgcatgag cctcgacacc ctgccggaac
     7921 cgttgacgca gcttcaggcg cgtctgaccg cgctggatat tgagcgggaa gcgattgagc
     7981 aggacagcgt gttttatccc gaaaccagcc cggagcggct ggcggaactg accgatttgc
     8041 gtgatgagct acaggcagaa gccgggcatc tggaagcgca gtatcagcag gaaaagcggc
     8101 ttgcgcagca gattatggcg ttgcgtcagg aaggggcaga cagcactgat ttgcaacagc
     8161 aactgcgaac gcatcagggc tttgcaccgc tgctggcgct ggatgtggac gcccgcgccg
     8221 tcgccactgt ggtggcggac tggaccggca tcccgctctc ttccctgctc agggacgagc
     8281 agagcgacct gctcagtatg gaacaaagcc ttgaaaaccg cgttgtcggg caaagcccgg
     8341 cgctctgcgc catcgcacag cggctgcggg cggctaaaac cggcctcacg ccggagaacg
     8401 gcccgcaggg ggtattcctg ctgaccggcc ccagcggcac cggtaaaacc gaaactgcgc
     8461 tcacactggc cgacaccctg tttggcggtg aaaaatccct tatcaccatc aacctctccg
     8521 aatatcagga gccgcatacc gtctcccagc ttaaggggtc tcctccgggc tacgttggct
     8581 acggtcaggg cggcgtactc accgaagccg ttcgcaaacg cccgtacagc gtggtgctgc
     8641 tcgacgaagt ggaaaaggcg catcgcgacg tgatgaacct gttctatcag gtatttgatc
     8701 ggggctttat gcgcgacggc gaaggccggg aaattgactt ccgcaacacc gtgattctga
     8761 tgacggctaa tctgggcagt gaccacatca tgcagctgct ggaggaaaaa ccggacgcca
     8821 cggacgcaga cctgcatgaa ctgctgtacc ccctgctgcg cgagcacttc cagcctgcac
     8881 tgatggcgcg ttttcagacg gtgatttacc gccctctggg acaggaagcg atgcgcgcca
     8941 ttgtggaaat gaaactggcg caggtggttc gtcgtcttcg tcagcactat gggctggaaa
     9001 cggaaatcaa cgacagcctg tatgacgcgc tgaccgccgc ctgcctgctg ccggacaccg
     9061 gggcgcgtaa tatcgacagc ctgctgaacc agcaaatcct gccggtctta agccagcagt
     9121 tgctggcgca acaggccgcg caccgtaaac cagcccagct acggcttggc tgggatgagg
     9181 aagacgggat tgtactggag ttcgctacgg aagagatgca ataacggagg ctgtcatggg
     9241 tattcagaat ttcgatcatt cacaccacaa gctcaaaatt cgtggcctgc aaagtccggt
     9301 ggatgtgctg accttcgaag gccgcgaaca actgagtacc ccgttccgct acgacattca
     9361 gtttaccagc agcgataaag ccatcacgcc ggagtcggtg ctgatgcagg acggcgcatt
     9421 cagcctgacg gcaccgccgg tacaggggat gccggtacag actgccctgc gcaccctgca
     9481 cggcgtcatc accggcttta aacacctgtc atcgtcacag gatgaagccc gttacgaagt
     9541 gcgccttgaa ccccgaatgg cgctgctggc ccgcagccgc cagaacgcca tttaccagaa
     9601 ccagacggtg ccgcaaatag tcgaaaaaat cctgcgcgag cggcaccaga tgcgcggtca
     9661 ggacttcgtg tttaacctca aaagcgaata cccgtcccgt gaacaggtga tgcagtacgg
     9721 tgaggacgac ctgacgttta tttcacgcct gctgtcggaa gtgggtatct ggttccgctt
     9781 tgccaccgac gcccggctga aaattgaggt tgtcgagttt tacgacgacc agagcggcta
     9841 tgagcgcgga ctgacgctgc cgcttcgcca tccttcaggg ctgtttgatg gtgaaacgga
     9901 agccgtatgg gggctgaaca ccgcatacag cgtggtggaa aaaagcgtca ccacgcggga
     9961 ctacaactac cgcaccgcca cagcagagat gatgacagag cagcatgacg ccaccggggg
    10021 cgataacacc acctatggct aagcctacca ctacgctgac aacttcctgc aaaaaggcga
    10081 caaggaggca gcggaaagcg gcgcgtttta tgcccgtatc cgtcacgaac gctacctgaa
    10141 tgaacaggcc attctgcagg gccagagcac cagttcactg ctgatgccgg ggctggaaat
    10201 cagggttcag ggcgacgacg cgcctgcggt attccgcaag ggcgtgctga ttaccggcgt
    10261 gacggccagc gcggcccgtg accgcagcta tgaactgacg ttcacggcga taccctactc
    10321 agaacgctac ggctatcgcc cggcgcttat cccccgcccc gtaatggccg gaacactccc
    10381 ggcgcgggtc accagtacgg tgaagaacga catctacgcc catatcgata aggacgggcg
    10441 ctaccgggtc aatctcgact ttgaccgtga tacgtggaag ccgggctacg aaagcctgtg
    10501 ggtacgccag tcgcgcccgt atgcgggaga cacctacggc ctgcacctgc cgctgctggc
    10561 gggaacggaa gtcagcatcg cctttgagga aggcaacccg gaccgaccgt atatcgccgg
    10621 ggtaaaacac gactcggcac acaccgacca tgtgaccatt cagaactaca agcgcaacgt
    10681 gctgcgcacc ccggcgaaca acaaaatccg cctcgatgat gagcgcggca aagagcatat
    10741 caaggtcagt accgagtacg gcggcaagag ccagttgaat ctgggtcatc tggtggatgc
    10801 cggaaaacaa cagcgcgggg aaggctttga actgcgtacc gatatgtggg gcgcggtgcg
    10861 ggcgaagaaa gggattttta tcagcgccga tgcgcaggat aaggcgcagg ggcaggtgcg
    10921 cgaaatggct ccggcgatgg caatactgga tggcgcacag tcacagatgc agtcgctgtc
    10981 cactgatgcg cagacgacga atgccgatcc ggcagatctg tcatcgcaga tagcgctgtt
    11041 gcagcaaagt gtaaaagatc tgacgcaggc cgtgatcctg ctaagtgcac ccaagggcgt
    11101 ggcgatcgcc agcggcgagc acctgcaact ggcggcgtcg aagaatgtga tagcgaacgc
    11161 aggcaacaac gcagatatcg gcgtagtaaa aaatatgttt atcggtgtgg gtcaggcgct
    11221 gagcgtgttt gtgcgtaaag cgggcatcaa gctgtttgcc aataaagggg cggtctcggt
    11281 acaggcacag aacgatctga tggaactgtt ggcacagaaa tcgatagaga tcaccagtac
    11341 ggaagatgag atcaagatca ccgcgaagaa gaaaatcacc cttaacggcg gtggcagcta
    11401 catccggctg gatgcctgcg ggatagaagc gggaacgccg ggagaatata acgttaaggc
    11461 cggatattac gggcgtaaac caaaggcgaa gctgacgccg gagctgatgg catttccggt
    11521 gattaagtct gaggatttta atcagagctt tattttgctg gatgaaaata ctgggcaacc
    11581 acttattaat tggccctatg aactagaact ggaaagtggg ctaaaaatga gtgggattac
    11641 tgatgaaaat ggaaatacag aactaatatc ctctgataag gaggaggtcg ttaatattag
    11701 tgtgtttgaa cccgatgagt ttttagacga tgacattaat taagacatat agcgagaata
    11761 taacatggca gataaatccg aaaagaaaaa agaaaccaca aataaatcag caaaaaaaac
    11821 actaacgaag aagagcgaaa aattaactcc agcaaaagac accgcaccaa aacaagtgaa
    11881 tgtagatcca gctataagat tgaaacaaat tcgtcaactt gtccgtaata ataataaatc
    11941 catcatggga gaggattata ttatttgtca aatctataaa gaatctagat ttaagcaatt
    12001 tgcaggtaag aataaacata atgcgaaagg cttaatgcaa atgcaacgaa atgcagtgag
    12061 gcaggttttt aaatatcgac aacaaaaaat aaaaggaaga atgacgactg ataaagagac
    12121 aaatgaagct ttcgctaatg ctgatacatt ttataaatct gataaaatat ttgatgaaaa
    12181 agaaaatatt aagattggca cagagtattt gcaatactgg atagataaag aagcaacaat
    12241 tgaggaggca tatcgtggaa cagatgaagc atactattct gttataaaac cttgcgctga
    12301 aaaactggct aaagatcctg ataacataca aatactaatg gagggaatag gaagatagta
    12361 tgcgcattat gttaatatta ctttgttttt ttctttcccc tgtttttcag gcgataagat
    12421 taaaatcgtg aaaacctgtc aactgaaaaa aaaatgaaag tgtgcagttg ctttccctta
    12481 gaaccattga cggtgataca ttatatctaa aattcagaaa tgttatcacc gaggcctttt
    12541 tagatactcc aactaaaagt tatgattttt ttggagatgt ggttctttct cagtgcataa
    12601 atggttctct tatctttgcg ctggaatatg gttctccata tataaaaggt tgtctggtaa
    12661 ctggttggga aaatgggttt aaaggtaaga actctcctga aggcttttgt tt
//
LOCUS       DAZUDJ010000105        12357 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.105, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000105 DAZUDJ010000000
VERSION     DAZUDJ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12357
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.105"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..467)
                     /locus_tag="ACHY1N_004451"
     CDS             complement(<1..467)
                     /locus_tag="ACHY1N_004451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="contractile injection system protein, VgrG/Pvc8
                     family"
                     /protein_id="HFS4046639.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLTQSLSSLFSLDLSLVSQQ
                     FLSLEFAQVLDKMAYLTVWQGDDVQLRVKGVVTWFELGENDKNQMLYSMKVHPPLWRA
                     GLRQNFRIFQNEDIKSILGTMLQENGVTEWSPLFSEPHPSREFCVQYGETDYD"
     gene            complement(1288..1500)
                     /locus_tag="ACHY1N_004452"
     CDS             complement(1288..1500)
                     /locus_tag="ACHY1N_004452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncH family protein"
                     /protein_id="HFS4046640.1"
                     /translation="MLCFLIYITLPFIQLVYFISSEKKLTIHIVQMFHLLSQVFYNLK
                     KFLMMDMLGVGDAININTNKNIRQVC"
     gene            complement(1576..2193)
                     /locus_tag="ACHY1N_004453"
     CDS             complement(1576..2193)
                     /locus_tag="ACHY1N_004453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HFS4046641.1"
                     /translation="MIKVYGVPGWGSTISELMLTLADIPYQFVDVSGFDHEGTSRELL
                     KTLNPLCQIPTLALENDEIMTETAAIALMVLDRRPDLAPPVGRAERQQFQRLLVWLVA
                     NVYPTFTFADYPERWAPDAPEQLKKNVIEYRKSLYIWLNSQLTAEPYAFGEQLTLVDC
                     YLCTMRTWGPGHEWFQDNATNISAIADAVCQLPKLQEVLKRNEII"
     gene            2460..3959
                     /gene="ansP"
                     /locus_tag="ACHY1N_004454"
     CDS             2460..3959
                     /gene="ansP"
                     /locus_tag="ACHY1N_004454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HFS4046642.1"
                     /translation="MSKHDTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     MLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMA
                     MGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIIVCQMRLRKAIKQGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IAALPIIGILLVIGWFGVRKRVAEIHSTAPVVEEDEEKQEIVFKPETAS"
     gene            complement(4072..5133)
                     /locus_tag="ACHY1N_004455"
     CDS             complement(4072..5133)
                     /locus_tag="ACHY1N_004455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="HFS4046643.1"
                     /translation="MHLRHLFSSRLRGSLLLGSLLVASSFSTQAAEEMLRKAVGKGAY
                     EMAYSQQENALWLATSQSRKLDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQT
                     LWFGNTVNSAVTAIDAKTGEVKGRLVLDDRKRTEEVRPLQPRELVADDATNTVYISGI
                     GKDSVIWVVDGENIKLKTAIQNTGKMSTGLALDSKGKRLYTTNADGELITIDTADNKI
                     LSRKKLLDDGKEHFFINISLDTARQRAFITDSKAAEVLVVDTRNGNILAKVAAPESLA
                     VLFNPARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVSVKQ
                     KSTKQQEATQPDDVIRIAL"
     gene            5375..7477
                     /gene="pqqU"
                     /locus_tag="ACHY1N_004456"
     CDS             5375..7477
                     /gene="pqqU"
                     /locus_tag="ACHY1N_004456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor PqqU"
                     /protein_id="HFS4046644.1"
                     /translation="MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTP
                     AAVSVVDGEEMRLATSRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIR
                     GIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVTTQTGQ
                     QPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVSTTRFTTHGYRDHSGAQK
                     NLANAKLGVRIDEASKLSLIFNSVDIKADDPGGLTKAEWKANPQQAPRAEQYDTRKTI
                     KQTQAGLRYERSLSAQDDMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQ
                     GIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNSGMPEYGQKGELRRDERN
                     LMWNIDPYLQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPA
                     GSLKYAMTDAWNIYLAAGRGFETPTINELSYRADGQSGMNFGLKPSTNDTIEIGSKTR
                     IGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVNA
                     SWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYVPEDGWYAGTEARYMGDIMA
                     DDENTAKAPSYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYE
                     PSPGRNYGVGMNIAWRFE"
     gene            complement(7513..8178)
                     /gene="mcbR"
                     /locus_tag="ACHY1N_004457"
     CDS             complement(7513..8178)
                     /gene="mcbR"
                     /locus_tag="ACHY1N_004457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415967.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid/biofilm transcriptional regulator
                     McbR"
                     /protein_id="HFS4046645.1"
                     /translation="MPGMGKMKHVSLTLQVENDLKHQLSIGALKPGARLITKNLAEQL
                     GMSITPVREALLRLVSVNALSVAPAQAFTVPEVRKRQLDEINRIRYELELMAVALAVE
                     NLTPQDLAELQELLEKLQQAQEKGDMEQIINVNRLFRLAIYHRSNMPILCEMIEQLWV
                     RMGPGLHYLYEAINPAELREHIENYHLLLAALKAKDKEGCRHCLAEIMQQNIAILYQQ
                     YNR"
     gene            complement(8376..9413)
                     /gene="curA"
                     /locus_tag="ACHY1N_004458"
     CDS             complement(8376..9413)
                     /gene="curA"
                     /locus_tag="ACHY1N_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415966.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent curcumin/dihydrocurcumin
                     reductase"
                     /protein_id="HFS4046646.1"
                     /translation="MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLR
                     TVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVSRVVESNHPDYQPGDWVLGYSGW
                     QDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
                     PVGATVGQIGKLKGCRVVGVAGGAEKCRHAIEVLGFDVCLDHHADDFAEQLVKACPKG
                     IDIYYENVGGKVFDAVLPLLNTSARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKR
                     IRLQGFIIAQDYGHRIHEFQKEMGQWVKEDKIHYHEDITDGLENAPQTFIGLLKGKNF
                     GKVVIRVAGDD"
     gene            9597..10115
                     /gene="mddA"
                     /locus_tag="ACHY1N_004459"
     CDS             9597..10115
                     /gene="mddA"
                     /locus_tag="ACHY1N_004459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HFS4046647.1"
                     /translation="MSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFE
                     ARTIAGYPVLVSEEDSVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLS
                     RLIDEARDCGKHVMVAGIESQNQASLHLHQSLGFVVTAQMPQVGTKFGRWLDLTFMQL
                     QLDERTEPDAIG"
     gene            10112..10561
                     /locus_tag="ACHY1N_004460"
     CDS             10112..10561
                     /locus_tag="ACHY1N_004460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFS4046648.1"
                     /translation="MNQSLTLAFLIAAGIGLVVQNTLMVRITQTSSTILIAMLLNSLV
                     GIVLFVSILWFKQGMAGFGELVSSVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLMLDIFRSHGVPLRALFGPICGAILLVVGAWLVARRSF"
     gene            complement(10562..10795)
                     /gene="ydcY"
                     /locus_tag="ACHY1N_004461"
     CDS             complement(10562..10795)
                     /gene="ydcY"
                     /locus_tag="ACHY1N_004461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2526 family protein YdcY"
                     /protein_id="HFS4046649.1"
                     /translation="MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTQ
                     QQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL"
     gene            complement(10881..11054)
                     /gene="ortT"
                     /locus_tag="ACHY1N_004462"
     CDS             complement(10881..11054)
                     /gene="ortT"
                     /locus_tag="ACHY1N_004462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orphan toxin OrtT"
                     /protein_id="HFS4046650.1"
                     /translation="MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRFLSAFLVGATW
                     PMSFPVALLFSLF"
     gene            11249..11344
                     /gene="yncL"
                     /locus_tag="ACHY1N_004463"
     CDS             11249..11344
                     /gene="yncL"
                     /locus_tag="ACHY1N_004463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HFS4046651.1"
                     /translation="MNVSSRTVVLINVFAAVGLFTLISMRFGWFI"
     gene            complement(11746..>12357)
                     /locus_tag="ACHY1N_004464"
     CDS             complement(11746..>12357)
                     /locus_tag="ACHY1N_004464"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HFS4046652.1"
                     /translation="EYSTMPVKNFSSVGAFSFPTCHFSGNIRIGRFCSIASNVKIMGG
                     NHPLNRFTTHMMTYNGEFDKFAMSEFERSWTLKPFITKPENPIIGNDVWIGNDVVLKG
                     GIAIGDGAVIAANSVVTKDVPPYAIVAGVPAKIIRFRFDSNVIDELLRIKWWNYNYSD
                     LPDNNKCDDINYFVEEMNRLISDGNIQERDYKKFNLSEVFRGL"
BASE COUNT         3167 a         2945 c         2870 g         3375 t
ORIGIN      
        1 aaatcgtaat cagtctcacc gtactggaca caaaactcac gggaaggatg cggctcgctg
       61 aacagcggac tccattcggt caccccgttt tcctgcaaca tcgtgccgag gatgcttttg
      121 atgtcctcgt tctggaagat acggaagttc tggcgcagac cggcacgcca cagcggcggg
      181 tgcaccttca tgctgtacag catctggttt ttgtcgttct cccccagttc aaaccaggtc
      241 accacacctt tcacccggag ctgtacgtca tcgccctgcc ataccgtcag gtaggccatt
      301 ttgtccagca cctgcgcaaa ttcaagggaa agaaactgct gactgaccag agaaaggtcg
      361 agggaaaaaa gtgaagagag tgactgggtg agatgaaagg aaaccaccgc aaacgcgtcc
      421 ggtggcaggc cgtccacttc aagtgtgaaa cgtaatccgg ttgacatagc aacctccgtg
      481 aaaatgaata ataatccgca catattgcat gtacaacatg tcgggcggat gagataagcg
      541 agtcgacatc tggcgttacc ggggaatatc agaaaaatgt catggttatg tgatgattta
      601 gtctgggatt ttacttcaga gaaacgggtg tctgtttagt caacaaaata atcacaaacg
      661 caacggatgg gttctcgacg ttattcacga caggctcgta cattacagcg agtaataaaa
      721 aacctgatat gcaaagtcaa accaatattc ataatgtctt tttattcaca acaataaata
      781 attcaataac aatcattgaa atgaatgatg atttgtataa ggaatatacg ctaccgcccc
      841 accctgataa catgatctgc acattgccat cttaacgtcg ttaaacactg gcttaatagt
      901 ggatatttca aattaggaat ttattaaatt cacctgatga atatcataag caaatagcat
      961 agaaaataat gacaattccc ccgaggggac catttccaaa gcactgcacc accacctggt
     1021 gcccggatga tcttgcttca gtggtaagag tacctgattc attgttccca aaatgatgtt
     1081 ttccccggcc ccgccaataa tgtgcagctc tcacgtgata atctattgat taggttatat
     1141 taagaatcaa catttaaaat acatccattt tcttgaataa atcaacatgt ttattaatca
     1201 attgctgttt tagctctgac tcatcaagct ctccatattt gtcctacaga taattgcgaa
     1261 taaatacaga gaacgccatt tatcctttta gcatacctgc cggatatttt tatttgtatt
     1321 aatattaatt gcatctccaa ctccgagcat atccatcatt aaaaactttt tgagattata
     1381 gaatacctgt gataacaagt gaaacatctg cacaatgtga atagttagtt tcttttcaga
     1441 ggaaatgaaa tagacaagct gaatgaaggg gagagtgata taaatcaaaa aacataacat
     1501 gaatttaatt aattacgccc atcattgtgg ataaagttac tgaataataa ataacataat
     1561 cctctggtat cccactcaaa taatttcatt cctttttaat acttcttgta atttcggtaa
     1621 ctgacataca gcatcagcaa tcgcactgat attcgtggca ttatcctgaa accattcatg
     1681 cccaggcccc catgtgcgca tagtgcaaag ataacagtcc accagcgtta gttgctcacc
     1741 aaacgcataa ggttcagcgg tcaattgtga attcagccag atataaagcg atttacgata
     1801 ttcaataaca ttcttcttta actgttcagg tgcgtcagga gcccaacgct cagggtaatc
     1861 ggcgaaagtg aatgttggat agacattagc aaccagccag accaatagcc gttgaaactg
     1921 ctgacgttcg gcgcgcccaa ccggtggcgc aaggtccggg cgacgatcga gaaccatcaa
     1981 tgcaatcgcc gctgtctccg tcataatctc gtcattttcc agcgccagtg tcggaatctg
     2041 acacaacggg ttcagggttt tcaataactc gcgtgaagtt ccctcgtggt caaaaccact
     2101 gacatcaacg aactgataag gaatatcagc cagtgttagc atcagctcac tgattgtaga
     2161 gccccatccg ggtacgccat acaccttaat catatgcccc tcacaatctt ttaaagatta
     2221 agtgtaggac agtacacagg ttaaccagca aaaggatttg tcattttttc gtcagttgta
     2281 ttaatcccct tcaggattgt aaggggatgt tttgcatcgt ttatcgataa cgggtaggat
     2341 gctgcgccga tagttttata cccataaaga ataatggtga taactatcat cgccaggatg
     2401 aataaacatt gttcatggca acttatatga ctttttcatt aaagcaatca gggagagcaa
     2461 tgagtaaaca cgacaccgac acttcagatc aacacgccgc gaaacgccgc tggcttaatg
     2521 cccacgaaga ggggtatcac aaagcgatgg gcaatcgcca ggtacagatg atcgccattg
     2581 gcggcgcgat tggcaccggc ttgtttttag gtgcaggagc ccgactgcaa atggcgggtc
     2641 cagcactggc actggtttat ttaatttgtg gcttgttttc gttttttatt ctgcgtgcat
     2701 tgggtgagct ggtgctacac cgcccttcca gtggcagttt tgtctcttat gcccgtgagt
     2761 ttttgggtga gaaagccgct tatgttgctg gctggatgta cttcatcaac tgggcgatga
     2821 cggggattgt tgatattacc gccgtcgctc tgtatatgca ttactggggt gcgtttggcg
     2881 gcgtgccgca gtgggtcttt gcgctcgctg cgctgaccat cgttggcacc atgaatatga
     2941 tcggtgtgaa atggtttgcg gagatggagt tctggtttgc gcttattaaa gtgctcgcca
     3001 ttgtgacctt tttggtcgtg ggtacagtgt tcctcggtag cggtcagccg ctggatggca
     3061 acaccactgg ctttcattta atcaccgata atggcggctt cttcccccac ggtttgctgc
     3121 ctgcgctggt gttgattcag ggcgtagtgt ttgcttttgc ctccattgaa atggtgggta
     3181 cagctgccgg agaatgtaaa gatccgcaga ccatggtgcc taaagcgatt aacagtgtga
     3241 tttggcgtat tggcctgttt tacgtcggct ccgtggtgtt gctggttatg ttattgccgt
     3301 ggagcgcgta tcaggcgggg caaagtccgt tcgtgacgtt tttctctaaa ctgggtgtgc
     3361 catatatcgg cagcattatg aacattgtgg tgctgaccgc tgccctctcc agcctgaact
     3421 caggcctgta ctgcaccggg cgtattctgc gctcgatggc gatgggcggt tccgcaccga
     3481 gttttatggc gaaaatgagt cgtcagcatg tgccgtatgc cgggattctg gcgacactgg
     3541 ttgtgtatgt cgtcggcgta ttcctcaact atctggtgcc gtcgcgcgta tttgagattg
     3601 tgttgaactt cgcgtcgctg ggaatcatcg cttcatgggc gtttatcatc gtgtgccaga
     3661 tgcgcctgcg taaagcaatt aaacaaggca aagcagcgga tgtcagtttt aaactgcctg
     3721 gcgcgccctt cacttcctgg ctgacattac tgtttttact gagtgtcctg gtgctgatgg
     3781 cgttcgatta cccgaacggg acttatacta tcgcggcgct gccgattatc ggtattctgc
     3841 tggttatagg ctggtttggt gtgcgcaaac gcgttgctga aattcacagc actgcgccag
     3901 tcgtcgagga agatgaagaa aaacaggaaa ttgtgtttaa gcctgaaacg gcgagttaat
     3961 tgcaaaattg cccggctacg tgccgggcaa attcagatta ctgacgaagg tgccggatgc
     4021 ggcgtgataa aagtcaggca agtctctccg ttttcaccct cgccatatct attacagcgc
     4081 aatacgaatc acatcgtctg gctgggtagc ttcctgctgt ttagtggatt tttgtttcac
     4141 actgacatac agcgttttgc catcggcaga cagcgccagg ctgtttggat gagtcggcgt
     4201 atcgaacgtt ttcaccactt tatagctttt cgcgtcaatc acactaactt tacctgcctg
     4261 acgatgcgtt acgtaggctt cattacgcgc tgggttaaac agcacagcca gtgattccgg
     4321 tgccgcaacc ttcgccagaa tattgccatt acgggtatcg accactaaca cttctgcggc
     4381 tttagaatcg gtgataaatg cacgctgcct ggcggtatca aggctaatgt tgataaagaa
     4441 gtgctctttg ccgtcatcca gcagcttttt acggctgagg attttattgt cggcggtgtc
     4501 gatggtaatc aattcgccgt cagcgttagt ggtgtaaaga cgtttgcctt tgctatccag
     4561 cgccagaccg gtactcattt taccggtgtt ctggatggcg gttttcagtt tgatattctc
     4621 gccatcaacg acccaaatca cgctatcttt accaatacca ctgatgtaaa cggtgttcgt
     4681 ggcatcatca gctaccagct cacgcggttg cagcgggcgc acctcttccg tgcgcttacg
     4741 atcatccagc accagacggc ctttcacttc gcccgttttg gcatctatcg ccgtgaccgc
     4801 gctgtttacg gtgttaccaa accacaacgt ctgagtcgtg ttattgatgg tggcaccaaa
     4861 cggcttgaga tcgttatgga tcgcctgcgt cacttccaga gtgaccggat caagacgata
     4921 aaccacgcca cctttatcca gtttgcggct ttgcgaagtg gcgagccaca gcgcgttttc
     4981 ttgctggcta taagccattt cgtaggcacc tttacctacc gctttacgca gcatttcttc
     5041 tgcggcctgc gtactgaatg atgaagcaac aagcaatgaa cctaacagta atgaaccacg
     5101 caggcgcgat gaaaacagat gacgtaaatg catgacgact ccctttgatg aaccaatatt
     5161 tttgctgctt cacaatgctt cgctaagcgt aatcatcgtt acgctcttgt tataaatggg
     5221 aatggtaatc attattttct caaatgtgga gcatttcttg ccgttacgac tacaattttc
     5281 tcaattaatt aacgtatcgt gccgtttcgt tttccataaa tttacaattt tattaccatg
     5341 acagcgtttt cccattctta acctggcttt tttcatgaag attttttccg tccgacagac
     5401 cgttttgccc gcactgcttg tcctttcccc cgttgttttt gccgctgatg aacagactat
     5461 gattgtcagt gccgcaccgc aggtggtttc agaactggat accccagcag cagtaagcgt
     5521 ggtggatggc gaggagatgc gcctggcaac atcgcgcatt aacttgtccg aatcactgac
     5581 cggcgtgcct ggtttgcagg tacaaaaccg gcagaactat gcgcaagatt tacagctgtc
     5641 gattcgcgga tttggctccc gctccactta cggtattcgc ggtattcgcc tgtatgtgga
     5701 cggtattccc gccaccatgc ccgacgggca agggcaaaca tccaacatcg atttaagcag
     5761 tgtgcaaaat gtggaagtgc tgcgtggccc cttctctgcc ctgtatggca acgcgtctgg
     5821 tggggtaatg aatgtcacca cccagaccgg acaacagcca ccaaccattg aagccagtag
     5881 ttactacggc agttttggca gctggcgcta tgggctgaaa gcaacgggcg caacgggaga
     5941 cggcacacag cctggcgatg tcgattacac cgtctcaacc acgcgtttta cgacccacgg
     6001 ctatcgtgac catagtggcg cacagaaaaa tttagctaat gccaaactgg gcgtacgcat
     6061 tgatgaagcc agcaaattaa gtctgatttt caatagtgtg gatatcaaag cagatgaccc
     6121 aggtgggcta accaaagcag aatggaaggc taatccacaa caagcgcctc gtgcagaaca
     6181 gtacgatacg cgaaaaacca tcaagcaaac tcaggctggg ttgcgctatg agcgtagcct
     6241 gagcgcgcaa gatgatatga gtgtgatgat gtatgccgga gagcgagaaa cgacccagta
     6301 ccagtcaata cccatggcac cacaacttaa cccgtcacat gcgggcggcg tgattaccct
     6361 gcaacgccat taccagggga tagacagccg ctggacacac cgtggtgaac tgggcgttcc
     6421 ggtcacgttc actaccggcc tgaactacga aaacatgagt gaaaaccgca agggctacaa
     6481 taacttccgc ctgaatagcg gcatgccgga gtacgggcaa aaaggtgagt tgcgtcgcga
     6541 cgaacgcaat ctgatgtgga acatcgatcc ctatttacag acgcagtggc agctgagcga
     6601 aaaactgtcg ctggatgctg gcgtgcgcta cagctccgtg tggtttgatt ccaacgacca
     6661 ttacgttact ccgggtaacg gcgatgacag cggtgatgcc agttatcata aatggctacc
     6721 tgccggttcg ttaaaatatg caatgaccga tgcctggaat atctatctgg cagccgggcg
     6781 aggttttgaa acgccgacga ttaatgagct gtcttatcgt gctgatgggc aaagcggtat
     6841 gaactttggt ttaaaaccat ccaccaacga tacaattgag atcggcagta aaacgcgtat
     6901 tggtgatggg ctgcttagtc tcgcattgtt tcagaccgac actgatgatg aaattgttgt
     6961 cgatagcagt agcggtgggc gtacgactta caaaaatgcc ggaaagaccc gtcgtcaagg
     7021 cgctgaactg gcatgggatc aacgtttcgc aggagatttt cgcgtaaacg cgtcctggac
     7081 ctggcttgat gcgacctatc gcagcaatgt ttgcaatgaa caggattgta acggtaatcg
     7141 gatgccaggg atcgcccgta atatgggctt tgcgtcgata ggttatgtac cggaagatgg
     7201 ttggtatgca ggcacggaag cgcgttatat gggcgatatt atggcagatg atgaaaatac
     7261 ggcaaaagcg ccgtcttata ctctcgtcgg cttattcacc gggtataaat acaattacca
     7321 caatttaact gtggatttat ttggtcgtgt cgataattta ttcgataaag aatacgttgg
     7381 ttctgtcatt gtcaatgagt caaacgggcg atattacgaa ccttcgcccg gacgaaatta
     7441 tggtgtcggc atgaatattg cgtggagatt tgagtaatta ccttgatgcc cggtatttgc
     7501 cgggcattta ctttaacgat tgtattgctg gtataaaata gcaatatttt gttgcataat
     7561 ttcagcaaga caatgtctgc atccctcttt gtcttttgct tttaacgcag cgagtaacag
     7621 atgatagttt tctatatgct cccgtaattc cgctggatta atcgcttcat agagataatg
     7681 taaaccaggc cccatcctga cccacagttg ctcaatcatc tcacacagga tgggcatatt
     7741 tgagcgatga taaatcgcta agcgaaatag cctgtttaca ttaatgattt gttccatgtc
     7801 gcccttttct tgcgcctgct gtaatttctc aagcaattcc tggagttccg ccaggtcttg
     7861 cggggtgagg ttttcaacag ccagagcaac tgccattaat tccagttcgt agcggatccg
     7921 attgatttcg tctaattgac gtttcctcac ttccggaact gtaaatgctt gtgcaggtgc
     7981 gacagaaagc gcattcaccg aaaccagacg taataatgct tcacgcacag gtgtaatact
     8041 catacctaat tgctccgcca gatttttagt aatcaggcgt gcgccaggtt ttaatgcgcc
     8101 aatactaagc tgatgtttca ggtcgttctc aacctgcaga gtcaaactga catgtttcat
     8161 ttttcccatt ccaggcattt taattccttc gcgtgttttc tgtccaaccc tgcctgcacg
     8221 gcagaaggag ttcacctggt gtattaaagt gaataatcat aaaccaccca cctttgttgt
     8281 tattagcagc agaacaatga cgtggttagt taattaaagc tgaaaataag ctttttgcct
     8341 ggatttttat ggcggcttac gccgccgttg aaactttaat catcacccgc gacgcggatc
     8401 accactttgc cgaagttttt acccttcagc aggccgataa acgtctgtgg cgcattctct
     8461 aaaccatcag taatatcttc gtggtagtgg attttatcct ctttcaccca ttgccccatc
     8521 tccttctgaa actcatggat gcggtgacca taatcctgag cgataataaa cccttgcaag
     8581 cgaatacgtt ttttcagcac cgttgccatc aacaggggta aacgatccgg accgggtggt
     8641 agctctgtag cgttatagct gctcactaag ccacaaacgg gaatgcgcgc agatgtatta
     8701 agtaatggta gcactgcatc aaatacctta ccgcccacgt tttcataata gatatcaata
     8761 ccttttgggc acgctttcac cagttgttcg gcaaaatcat ccgcgtggtg atcaagacaa
     8821 acatcgaagc ccagcacctc gatagcatgg cggcattttt ccgcgccacc ggcaaccccc
     8881 accaccctgc aacctttaag tttgccgatt tgccccaccg ttgctcccac aggacctgtc
     8941 gccgcagcta ccaccaacgt ttcgccctct ttaggctgac cgatatccag cagccccata
     9001 taagcggtaa agcctggcat ccccagcaca cccagcgacc acgatggatt ttgcggatga
     9061 tcgccaagtt tcaccagatc atcaccactg gatatgtcat agtcctgcca tccactgtag
     9121 cccagcaccc agtcgccagg ctgataatca ggatgattcg actccacaac acggctcacc
     9181 gtgccgccga ccatcacgcc gccaatatca acaggcggtg aataagatgg ctcatcgctc
     9241 atacgtccac gcatatacgg gtccagggac aaataaactg tgcgcagtaa cacctgtcct
     9301 tcacccggtg tggcgacatc atcttcttca agacggaaat tctccggaac cggtgcgcca
     9361 tgtggacgcg aggccagaac ccaacggcgg ttacgctgct tttgttgccc cataatgctc
     9421 tcctgtgctt ttggcatgaa tccatcaata gtagcaggct cgcaggattg gttttgtttg
     9481 cagccgtcac atcccctctg caacacgcaa taatttcatc gaggaatccg ttgcttcggg
     9541 ctgttttcga tagtattgat aacatcatca tcatcattat tttattgagg ccagacatgt
     9601 ccatccgttt tgcccgcaaa gccgactgtg ctgccattgc ggaaatttat aaccacgccg
     9661 tgttgtatac ggcggctatc tggaatgacc aaacggtgga tgcagataat cgcattgcct
     9721 ggtttgaagc gcggaccata gcaggttatc cggtgctggt aagtgaagaa gatagcgtag
     9781 tgacgggata tgcctcgttt ggcgactggc gtagtttcga tggttttcgc cataccgtgg
     9841 aacattcggt ttatgtccat cccgatcatc agggcaaagg tctggggcgt aaattgttaa
     9901 gccgattgat tgatgaagcg cgggattgcg ggaagcatgt catggtcgcc gggatcgaat
     9961 cgcaaaatca ggcctcgctg catctgcacc agtcgctggg atttgtcgtc accgcacaaa
    10021 tgccgcaggt gggcactaaa tttgggcgct ggctggatct gacatttatg cagttgcaac
    10081 tcgacgaacg cactgaaccg gacgcgattg gatgaatcag tcgctcaccc ttgctttttt
    10141 gattgccgcc ggaattggtc tggtagtcca gaacacgctg atggtgcgca tcacccagac
    10201 ctcctctacc attctcatcg ccatgttgct gaactcactg gtggggattg tgctctttgt
    10261 ttctatttta tggtttaaac aaggcatggc ggggtttggc gaactggtgt ccagcgtgcg
    10321 ctggtggaca cttatacccg gcttgctggg atcgtttttt gtcttcgcca gtatcagcgg
    10381 atatcagaat gtgggagcgg cgacaactat tgcagtactg gtcgccagcc agctaattgg
    10441 cggtctgatg ctggatatct tccgcagtca tggcgtacca ctacgggcgt tgttcggccc
    10501 aatttgtggc gcaattttac ttgtggttgg cgcctggttg gtagccagac gctcatttta
    10561 atcagaggat ggtgccgcct ttggttaact gttcgtggcg cgcttccata tcttctttat
    10621 gcttgcgacc gtgatgagca atagcggtgc gcaaacgctg ctgctgggtg tagcgatctt
    10681 cccgacttaa ctccgcgtca tcgctcaggg cgattaataa ttcgttcata tgggcaatga
    10741 cgctctcttc aatcgcggca tccacgcgcg cgatgacttc atccagatgc gacatacttt
    10801 ctccttaacc acttgtgaaa tttatcgatt catccaaatg atataagtct gcgtggtgcc
    10861 gtcaagccag tgagtaagat ttaaaacagt gaaaacaaca gcgccaccgg gaaactcatc
    10921 ggccatgttg cccccaccag aaaggcgctt aagaaacgga tgcgtttctt atcgtgagaa
    10981 agaaaccagg tgataagaaa tgcgattgct gccataaccg cataaaaaac aagcatatgt
    11041 tgatagagag acatgtacgg gcgtccagcc agatgaataa aacgcgcgca aatatgcgtc
    11101 attttttgac gtgcatcaag ttttttcacc agtttgagaa aaaatcatca aacagcaact
    11161 tgcccttatc catcttcaga atgagtatta ttgcggattt tcttaacccg tactatacac
    11221 ataggggcaa tgataaaagg tggcaaaaat gaatgtttcc agtagaactg tagtactgat
    11281 aaatgtcttt gctgctgttg gtttgtttac tcttatctct atgagatttg gctggtttat
    11341 ttgatgtagt gattttgcac gcagcacata ctgtcagaga aatcaactct ctgacagtac
    11401 gcaagatctt ctcatactct ccaggtttac aacattatcc ttaatattta cttctttttg
    11461 ctggcatcta cattgaaatg agtagaaaac atccccctac tgtcgtctat acaaacagct
    11521 tactgattca aacggaatct tgttttcaca tttttctatc atgaatactt tatacgcgcg
    11581 ggagtctata aatgctttat actttcaagg aataacgtaa atataaaaag atggcgtaaa
    11641 gtatatgcat ggcaggatgt ttgcaacctc cttgatgacg ctgccccatt gaaattgcaa
    11701 accccgccct ggttatcttg cccatttatc atgcaaaaca gataattata ggcctctgaa
    11761 tacctcagaa agattgaatt ttttatagtc cctctcttga atatttccat ctgatatcaa
    11821 tcgattcatc tcttcaacaa aataatttat atcatcacac ttgttattat ccggaagatc
    11881 tgagtagtta taattccacc attttattct caacagttca tcaataacat ttgaatcaaa
    11941 cctaaatctg attatttttg caggaactcc tgcaactatg gcatatgggg gcacatcttt
    12001 ggtaacaacg gaattggcag caataacagc accatcacct attgcgatgc cacctttcaa
    12061 tacaacatca tttcctatcc agacatcatt tcctataatc ggattttcag gtttggtaat
    12121 gaatggtttc aatgtccagc tacgttcaaa ttcactcata gcaaacttat caaattcacc
    12181 gttataagtc atcatgtgag tagtaaaacg attcaaagga tgatttccac ccattatttt
    12241 tacatttgat gcaatactac aaaatcgacc tatacgtata ttccctgaaa aatggcaggt
    12301 cggaaatgaa aaagcgccga cactggagaa atttttcaca ggcattgttg aatattc
//
LOCUS       DAZUDJ010000106        12303 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.106, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000106 DAZUDJ010000000
VERSION     DAZUDJ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12303
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.106"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            78..554
                     /locus_tag="ACHY1N_004465"
     CDS             78..554
                     /locus_tag="ACHY1N_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1441 family protein"
                     /protein_id="HFS4046653.1"
                     /translation="MDGELKNMKLNINQLAALSGLHRQTVAARMADVPLAPGSNEKKK
                     LYLLTDLITSLLEKPPSSEDEDMDPHARKAWYQSERERLKFQHETVQLVPVSDVRRSF
                     SVVVKAIVQVLETWPDRLERDRGWTASQLNEVQIVVDEIRDTLEKAVIDCCDEADM"
     gene            551..2674
                     /locus_tag="ACHY1N_004466"
     CDS             551..2674
                     /locus_tag="ACHY1N_004466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HFS4046654.1"
                     /translation="MNQVNESHSRASDIWREVASLFRPPSRLPVAEAIRRYMRVPRGA
                     NTSGPWESSLTPYMIDPINTLSAREYDAVVFVGPARTGKTEGLIDGWIVYGIICDPAD
                     MLVVQMTETKAREHSRTRLSRTFRHSPEVSKRLSPSRNDNNVHDKMFLDGSFLKIGWP
                     SITVFSSSDYRRVALTDYDRFPENVDGEGDAFTLASKRTTTFMSSGMTLVESSPGRDI
                     TDTKWRCGGAHEAPPTTGILSLYNRGDRRRWYWPCPHCGEYFQPVMDNMTGYRNNPDF
                     VAAGQAARLMCPHCRGLIAPEQKRELNNQGIWLREGERAAADGSITGTPRNSRIASFW
                     MEGPAAAFQTWEQLIFKLLAAEEEYERTGSEETLKAVVNTDIGRPYLPRSATEQRKSE
                     LLEQRAEPFPRRSVPDGVRFIEATVDVQGGKNRRFVVQITGYGEQGERWIVDRYNIRH
                     SLRCSPNGESLPVDPAAYPEDWDLLLTDVFHKTWPLASDPDVRMRLMAMAVDTGGEAG
                     VTDNAYRFWRRCRSDGLGNRVFLFKGDGLRRDRLINRTFPDNTGRSARRARASGDVAL
                     WLVQTDAFKDRVNNALWRDTPGPNYIHFPDWLGRWFYDELTYEERGSDGKWRKPGRGA
                     NEAFDLLVYADALAVLHGYEKIRWPSAPDWAQRETWLVFPQERSGETVSPELTAGAEK
                     RRRRKKKLRTERAEDNPWITSGGWL"
     gene            2671..2883
                     /locus_tag="ACHY1N_004467"
     CDS             2671..2883
                     /locus_tag="ACHY1N_004467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310989.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046655.1"
                     /translation="MSTEEAREMIQRYREAEMAVLEGKSVIFNGQQLTLESLSQIRAG
                     RQEWERRLAAMVSRRRGKPGFKLARF"
     gene            2961..4385
                     /locus_tag="ACHY1N_004468"
     CDS             2961..4385
                     /locus_tag="ACHY1N_004468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4046656.1"
                     /translation="MAYEAVKPTRTHKARRENRSADQLSKYGAVSLREQARFLDINHD
                     LVIGVFDKLEERVIGARGIIVEPQPLRKNGEMAAELAADIRRLWAEWSVSPDVTGQYT
                     RPVLERLLLRTWLRDGEVFAQMVSGAGNGLERTAGVPFWLEAMEPDFVPMRTDESAGL
                     NQGVFLDEWGRPKKYLVYKNYPVSGRQSDTKEIAAGKMIHLKFTRRLHQTRGSSMLSG
                     VLMRISALKEYEDAELTAARIAAALGLYIRKGDGQDYEDPGIKETEREVHITPGIIYD
                     DLRKGEDIGMVKSDRPNPNLETFRNGQLRAVAAGSRLSFSSAARNYNGTYSAQRQELV
                     ESTDGYLILQDCFIGAVTRPVYRTWLNMVVAAGLLKIPADVEMKTLYNATYSGPVMPW
                     IDPVKEAEAWRIQIRGGAATESDWVRAGGRNPDEVKRRRKAEIDENSRLGLVFDTDPV
                     NDKGGNSAGTERQYQRDTESQHEE"
     gene            4330..6354
                     /locus_tag="ACHY1N_004469"
     CDS             4330..6354
                     /locus_tag="ACHY1N_004469"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ClpP-like prohead protease/major capsid protein
                     fusion protein"
                     /protein_id="HFS4046657.1"
                     /translation="MPELNDSISATPKASMKNKSWFRMQAGGPGDADIYIYDEIGFWG
                     VTAKQFVSELNALGDITHINLHINSPGGDVFEGIAIFNALKNQGATITVYVDGVAASM
                     ASVIAMAGDTVIMPENAFMMIHKPWGFSGGDAEDMRSYADLLDKVESVLLPAYAQKTG
                     KTTDEIAAMLADETWMSGAECLAHGFADQVTPAVEAMACIQSKRTEEFKKMPESIRNM
                     ITPPRNSAPRDTTVTIPAPAVTEPSPVPAVSDEATIRARVMAEQKARMSGINDLFAMF
                     GGRYQTLQAQCVADPDCSLEMARERLLNEMGKESSPTNKNTPAHIYAGNGNFVGDGIR
                     QAMLARAGFENVEKDNAYNGMTLREWARMSLTERGIGVASYNPMQMVGLALTHSTSDF
                     GNILLDVSNKGLIQGWEESEETFQKWTRKGRLSDFKTAYRVGMGGFGSLRQVREGAEY
                     KYITTSDRKETIALATYGEIFSITRQAIINDDLNMLVDVPMKMGRAAKATIGDLVYKV
                     LTDNPKLSDGKALFHADHKNIATGGISVSGLDAARQMMRLQKEGDRALNIRPAFMLVP
                     VALETVANQTIKSASVKGADANAGVINPIQNFAEVIAEARLDAADPKTWYLAAAQGTD
                     TIEVAWLDGVDTPYIDQQEGFTTDGIATKIRIDAGVAPLDWRGLVRSSVA"
     gene            6442..6768
                     /locus_tag="ACHY1N_004470"
     CDS             6442..6768
                     /locus_tag="ACHY1N_004470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid cement protein"
                     /protein_id="HFS4046658.1"
                     /translation="MAKNFVQDGTTIELVNAGDQTILSGAAVVVGSMVAVAITDIPAG
                     EAGDGFAEGVFLLPKQSADDIQSGAVVYLKDGVVQLAADGAVAAGVAWENAPANSATV
                     AVKINV"
     gene            6761..7042
                     /locus_tag="ACHY1N_004471"
     CDS             6761..7042
                     /locus_tag="ACHY1N_004471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA breaking-rejoining protein"
                     /protein_id="HFS4046659.1"
                     /translation="MSDLFTRMCCRMDVATVRVMGKQAEINGVVYDVMPEEESAEMGA
                     LSGSQLSLVVFSARYRPARHDVVVFAGRTLTVTRYDTYNGKPRIFVEQE"
     gene            7045..7668
                     /locus_tag="ACHY1N_004472"
     CDS             7045..7668
                     /locus_tag="ACHY1N_004472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4046660.1"
                     /translation="MAIKGLAQAMKNLDAIDRRAVPRASATTLNRVAGAIIAKTASSV
                     ARELAVPRRLIRARIRLSPARPDKVYAKVYINTGNLPAIKLGEARVRLSRRKRRKKGQ
                     RAALKGGGSVLIVGKRRIPDAFITRLANGRWHVMQRMPWASSSTGADSKGRPKRHRLP
                     IEVVKITTAGPLAETFERERDRMYREKLPAQMMKAMTHQLRLVLKRK"
     gene            7681..8079
                     /gene="gpU"
                     /locus_tag="ACHY1N_004473"
     CDS             7681..8079
                     /gene="gpU"
                     /locus_tag="ACHY1N_004473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail terminator protein"
                     /protein_id="HFS4046661.1"
                     /translation="MKHREIRAAVLSALKENISERVSWFDGRPVFIDEQELPAVAVYL
                     TDASAADEFVDEGTWEATLHIEVFLRAKEPDSALDMWMEEKILPALEAVPGLSALLLK
                     MNLQGYDYRRDDEFMMWGSADLLWKITYEM"
     gene            8087..8839
                     /locus_tag="ACHY1N_004474"
     CDS             8087..8839
                     /locus_tag="ACHY1N_004474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4046662.1"
                     /translation="MATPNPLEPVKGAGTTLWVYNGKGDAYANPLSDDDWQRLAKVKD
                     LTPGEMTAEPYDDNYLDDEDADWTATGQGQKSAGDTSFTLAWKPGEEGQKGLIGWFES
                     GDVRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSEITP
                     ATAIKVTPTSGTVAKGKTTTLTVSFEPESATDKTFRAVSADPSKATISVKDMTITVNG
                     VATGKVQIPVVSGNGQFAAVAEVTVTEAGAAG"
     gene            8853..9275
                     /locus_tag="ACHY1N_004475"
     CDS             8853..9275
                     /locus_tag="ACHY1N_004475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HFS4046663.1"
                     /translation="MFLKTEQFEYNGVSVTLSELSALQRFDYIKFVSDAEQQETTKHD
                     VVHINQRYLETASLLVAMSLWHSHSLKGTLASPETEMQQIRREVMLGWPADALNQATN
                     RVLYLSGMLDNRHDADPEPTGKTEATEPVTSKKHSKAS"
     gene            9302..9604
                     /locus_tag="ACHY1N_004476"
                     /pseudo
     CDS             9302..9604
                     /locus_tag="ACHY1N_004476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310194.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
     gene            9654..12299
                     /locus_tag="ACHY1N_004477"
     CDS             9654..12299
                     /locus_tag="ACHY1N_004477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4046664.1"
                     /translation="MAGNFADLTAVLTLDSARFSEEAARVKKELGETSALADLMSGKV
                     SQSFRKQADAAEQSLSRQALAAQKAGISVGQYKAAMRTLPAQFTDIVTQLAGGQNPFL
                     IMLQQGGQISDSFGGPLSLLTLLKEELLGIRDASESSEESLSDTANALAENARNAGEL
                     GRFMSVARVAAGGGVAVLAALAAAAWQAEQADRALLRSLTLTGGAAATTTAELWKMAG
                     VISDEAGGGIRQAAENLARLAESGKYTAGQLRIMGETSQRWLQTVGDDAGKVEKAFEG
                     IAADPVKALASLNQQYNFLSVSQLRHIDELERTKGKQVAVTEAMSLFADVMNARLEQL
                     DKAATPVEKIWDDVKTWTSDAWAWIGDHTLGALSLITDVVAGTVEQVKLLLVQGDLAL
                     AEFIQSAWETTKNVPGVGALFGELAEENRVFIEKTKRDELALRKSIAERDARIRQGEM
                     GYINRSRATGVSKGPGQQEAVSRLAEELTGKKHTSPKTRSAGEREEEQAREALLALEA
                     ELRTLEKHSGANEKISRQRRDLWKAESQYAVLKEAATKRQLSEQEKSLLAHKDETLEY
                     KRQLAELGDKVEYQKRLNELAQQAVRFEEQQSAKQAAISAKARGLTDRQAQRESEAQR
                     LRDVYGDNPAALAKATSALKNTRSAEEQLRGSWMAGLKSGWGEWAESATDSFSQVKSA
                     ATQTFDGIAQNMAAMLTGAEADWRGFTRSVLSMMTEILLKQAMVGIVGRIGSAIGGAF
                     GGGASASSGTAIQAAAANFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGN
                     LYRLMRGYAEGGYVGGAGSPAQMRRAEGINFNQNNHVVIQNDGTNGQAGPQLMKAVYD
                     MARKGAQDELRLQLRDGGMLSGSGR"
BASE COUNT         2900 a         2910 c         3927 g         2566 t
ORIGIN      
        1 gacatcttta tatggcggca tttctttaca aaaaaacaga gtcacttctg ttctgcggtt
       61 tatgtggagg gatgtaaatg gacggcgagc tgaaaaatat gaagttaaat attaatcaac
      121 tggcagccct ttcaggtctg caccggcaga ctgttgccgc cagaatggcg gatgttcctc
      181 ttgcaccagg cagtaatgaa aagaaaaaac tgtatctcct gacggatttg ataacttcgt
      241 tgctggaaaa accaccatct tccgaagatg aggatatgga tcctcacgct cgtaaggcat
      301 ggtatcagtc cgagcgcgag cgtcttaaat ttcagcatga aactgttcag cttgtgccag
      361 tcagtgatgt caggcggtcc ttttctgtcg tggtgaaagc gatagttcag gtactggaaa
      421 cctggcctga ccggctggag agggacaggg ggtggactgc atcacaactg aatgaagtac
      481 agattgtggt tgatgagatc cgcgacacac tggaaaaggc agtcattgac tgttgtgatg
      541 aggccgatat gtgaatcagg tgaacgagag ccatagccgc gcatccgata tctggcgcga
      601 agtggcctcg ctgtttcgcc cacccagccg gttaccagta gcggaagcca tcaggcgtta
      661 tatgcgggtt ccacggggag ccaatacttc cggtccgtgg gagtcatcgc tgacgcccta
      721 tatgattgac cccattaata cattatcagc ccgtgaatat gacgcggtgg tgtttgtggg
      781 acctgcgcga accgggaaaa ccgaagggct gattgatggc tggattgtgt acggcatcat
      841 ctgtgatccg gcggatatgc tggtggtgca gatgactgag acgaaggcgc gtgagcattc
      901 cagaacgcgt ctttccagga cgtttcgcca cagtccggag gtcagcaagc gcctcagtcc
      961 ttcccgtaat gacaacaacg tccacgataa aatgtttctt gacggctcct tcctgaagat
     1021 tggctggccg tcgatcaccg tcttttcctc ttcggattac cgtcgtgtgg cgctgacgga
     1081 ttatgaccgt ttccctgaaa atgtggacgg ggaaggggat gccttcacgc tggcctcaaa
     1141 gcgtaccacc acctttatgt cctcggggat gaccctggtc gagagttcac cggggcggga
     1201 tatcaccgat accaaatggc gttgtggtgg cgcacatgag gcaccgccaa caacggggat
     1261 cctgtcactg tataaccggg gagaccgccg ccggtggtac tggccgtgtc cgcactgcgg
     1321 ggaatatttt cagccggtga tggataacat gaccggatac cggaataacc cggattttgt
     1381 ggctgccggt caggctgccc gtctgatgtg tccgcattgt cgcgggctga ttgcccctga
     1441 gcagaaacgc gaactgaata accaggggat ctggcttcgt gaaggtgaac gggcggcggc
     1501 ggacggcagt atcaccggaa cgccacgaaa ctcccggatt gcgtcatttt ggatggaggg
     1561 gccagctgcg gcgtttcaga cctgggaaca actgattttt aaactgctgg cggcagaaga
     1621 agagtatgag cgaaccggca gtgaagagac cctgaaagcg gtggtgaaca ccgatatcgg
     1681 acgaccctat ctgccccgtt cagccacgga acagcgtaaa agtgaactgc ttgaacagcg
     1741 tgccgagccg tttccccggc gatctgtgcc ggatggtgtg cgttttattg aggcaacggt
     1801 tgacgtacag ggcggtaaaa atcgccgttt tgttgtgcag atcacaggat acggagagca
     1861 gggggaacgc tggattgttg atcgctacaa catccggcat tcactgcgct gcagtcccaa
     1921 cggtgaaagt ctgccggttg atccggcggc atatccggag gactgggatt tgttgctgac
     1981 ggatgtgttc cataaaacat ggccgctggc ttctgatccg gatgtgcgca tgcgtctgat
     2041 ggccatggcg gtggatacgg gaggggaagc cggggtgaca gataacgcct atcgtttctg
     2101 gcgtcgttgc cggagtgacg gactgggcaa cagggtgttt ctgttcaagg gggatggact
     2161 tcgccgtgac aggctgatta accgaacctt cccggataat accggcagaa gtgcccgccg
     2221 tgccagagcc agtggcgatg tcgcgctgtg gctggttcag acggatgcgt ttaaggatcg
     2281 tgtaaataat gccctgtggc gtgacacacc agggccgaac tatatccact ttcccgactg
     2341 gctggggcgg tggttttacg atgagctgac ctatgaagag cgcggcagtg acggaaaatg
     2401 gcgaaaaccg ggcaggggcg ctaacgaagc gtttgacctg ctggtttatg cggatgcgct
     2461 tgccgttctg catggttacg aaaagatccg ctggccctcc gcaccggact gggcacagcg
     2521 ggaaacgtgg ctcgtcttcc cgcaggagcg ttctggtgaa acggtatccc cggaactgac
     2581 ggccggggca gaaaaacgcc gtcgccggaa gaaaaaactg cggacggagc gtgcggaaga
     2641 taatccatgg ataacatcag gaggctggtt gtgagcacag aagaagccag agaaatgata
     2701 cagcggtacc gtgaagcgga aatggccgta ctggagggaa agtctgtcat cttcaacggg
     2761 cagcaactga cgctggaaag cctttctcag atccgcgccg gacgtcagga gtgggaacgc
     2821 aggcttgccg cgatggtgag ccgcaggcgg ggaaaaccgg gatttaaact ggcgaggttt
     2881 taatggcaat tattgatgat gtgatcggcg tgttttcccc cgggtggaaa gcagccagac
     2941 tgcgttcaag ggcgtgaatc atggcctatg aggcggtgaa accgacccgg acacataaag
     3001 cccggcggga aaatcgctct gctgatcagc tcagtaaata cggtgcggtt tccctgcggg
     3061 agcaggcccg ttttctggat atcaatcatg acctggtgat tggtgtgttt gacaagctgg
     3121 aagagcgggt gattggtgcc aggggaatta ttgtggagcc tcagccatta cgaaaaaacg
     3181 gggaaatggc ggctgagctg gctgcggata tccgccgttt gtgggctgaa tggtccgtga
     3241 gtccggatgt gacagggcag tatacccgtc ctgtgcttga acgtttactg ctgcggacct
     3301 ggctgcggga tggtgaagtg tttgcgcaga tggtcagtgg tgcgggaaac ggtctggaac
     3361 ggacggcggg agtgccattc tggcttgagg cgatggagcc ggattttgtt cccatgcgca
     3421 ctgatgaatc cgccggactg aatcaggggg tttttcttga tgagtgggga agaccgaaaa
     3481 aatatctggt ttataaaaat tatccggtca gcggccggca gagtgatacg aaagaaatcg
     3541 ctgccggaaa aatgatccac ctgaagttca ctcgtcgtct gcatcagacg cgaggctcat
     3601 ccatgttatc gggggtgctg atgcggatca gtgcccttaa ggagtatgag gatgcggaac
     3661 tgacagcggc gcgtattgct gcggcgctgg gactgtatat ccgtaaaggt gacggacagg
     3721 actatgaaga tccggggatc aaagagaccg agcgggaagt ccatatcacc ccgggtatta
     3781 tttatgacga tttgcgcaag ggcgaggata tcggcatggt caaatctgac cgtcccaatc
     3841 ccaaccttga aactttccgc aacggccagt tgcgtgcagt ggcagcaggc agtcgtctga
     3901 gtttttccag tgcggcgcgt aactataacg gcacctacag cgcccagcgg caggagctgg
     3961 tcgagtccac ggatggttac ctgatcctgc aggactgttt tattggcgcg gtaacccgcc
     4021 cggtgtaccg gacatggctg aatatggtgg ttgcggcagg tctgctgaaa attccggcgg
     4081 atgtggagat gaaaacgcta tataacgcga cgtattccgg tccggtgatg ccgtggatcg
     4141 acccggttaa ggaagctgaa gcctggagaa ttcagatccg gggtggtgca gcgacagaat
     4201 ctgactgggt gcgtgccggt gggcgcaatc cggatgaggt caaacgtcgc cgcaaggctg
     4261 aaattgatga aaacagcaga ctggggctgg tctttgatac tgaccccgtc aacgacaaag
     4321 gaggcaacag tgccggaact gaacgacagt atcagcgcga caccgaaagc cagcatgaag
     4381 aataaatcct ggttcaggat gcaagctggg gggccgggtg acgcggatat ttatatttat
     4441 gacgagattg gtttctgggg agttaccgcg aagcagtttg tcagcgaact gaatgcactg
     4501 ggtgatatca cccacattaa tctccatatc aattcaccgg gtggcgatgt ctttgaaggc
     4561 atcgccattt ttaatgccct gaaaaatcag ggggcgacca ttaccgtgta tgtggatggc
     4621 gttgccgcct cgatggcatc tgtgattgcg atggccggtg atacggtcat tatgccggaa
     4681 aatgccttca tgatgatcca taagccatgg ggattcagtg gcggggatgc tgaggatatg
     4741 cgcagttatg ccgatttgct ggataaagtc gaatcggtac tgttgccagc ctatgcgcag
     4801 aaaaccggaa aaaccaccga tgaaattgcc gccatgctgg cggatgaaac ctggatgtcc
     4861 ggtgccgaat gtctggcaca cggatttgct gaccaggtga cacccgctgt tgaggcaatg
     4921 gcatgtattc agtcaaaacg tacagaggaa tttaaaaaga tgccggaatc catccgaaac
     4981 atgattactc cgccacgcaa cagtgccccg cgtgatacca cagtgacaat ccctgcaccg
     5041 gcggtaacag aaccatcacc ggtaccggca gtgtctgatg aggcgaccat tcgcgcccgc
     5101 gttatggctg agcagaaagc ccgcatgtca ggcattaacg atctgtttgc catgttcggc
     5161 ggtcgctatc agacgcttca ggcacagtgc gtggctgatc ctgactgttc gctggaaatg
     5221 gcccgtgaac gtctgctgaa tgaaatgggc aaggagtcct cgccgaccaa caaaaataca
     5281 ccggcccata tttatgccgg aaacggcaat tttgtggggg acgggatccg ccaggcgatg
     5341 ctggcccgtg ccggatttga aaatgtcgag aaggataacg cctataacgg gatgaccctg
     5401 cgtgaatggg ctcgcatgtc actgacggag cgcggtattg gggtggccag ttataacccc
     5461 atgcagatgg tcgggctggc gctgacgcac agcacctctg attttggcaa tattctgctg
     5521 gatgtgtcga acaaggggct gatccagggc tgggaggaat cagaagaaac cttccagaag
     5581 tggacccgta agggacgcct gtcagacttc aaaacagcgt atcgcgtggg gatgggcggt
     5641 tttggttctc tgcgccaggt tcgtgagggg gcggagtata aatacatcac cacctcagat
     5701 cgcaaggaga ccattgcact ggccacttac ggggagattt tctccatcac ccgccaggcc
     5761 attatcaatg atgatctgaa tatgctggtg gacgtgccga tgaagatggg gcgtgcggcg
     5821 aaggcaacga ttggtgacct ggtctacaag gtgctgacgg ataacccgaa actgtccgac
     5881 ggtaaggcgc tgttccatgc cgatcacaaa aatattgcca ccggggggat ctccgtttcc
     5941 ggactggatg cggcccgtca gatgatgcgc ctgcagaaag aaggcgatcg tgccctgaat
     6001 atccgtccgg cctttatgct ggtaccggtg gcactggaga cggtggcgaa ccagaccatc
     6061 aaatcggcca gtgtgaaagg ggcggatgca aacgccggtg tcattaaccc tatccagaac
     6121 tttgctgagg tgattgcaga agcgcgtctt gatgcggcag acccgaaaac ctggtatctg
     6181 gcggcggcac agggcactga caccattgaa gtggcctggc tggatggtgt ggacacgcca
     6241 tacattgatc agcaggaagg tttcaccact gacggcattg ccacaaaaat ccgtattgat
     6301 gccggagtgg caccacttga ctggcgcggg ctggtgcgtt cgtcggtggc ctgataaccg
     6361 cgttatcaca atcactgccc gaaagggctt tttttatgcc tgaaaaacag ccccacaggg
     6421 gctgtccgga gaaacagcat tatggcgaaa aattttgtac aggacggtac caccattgaa
     6481 ctggtgaatg ccggagatca gaccatcctg agcggtgctg cggtggtggt cggcagtatg
     6541 gtggccgtgg ccattaccga tattcctgcc ggtgaggccg gtgacggttt tgccgaaggc
     6601 gtgttcctgc tgcccaaaca gtctgctgac gacattcagt ccggcgcggt ggtttatctg
     6661 aaggacgggg ttgtgcagct ggctgcagac ggtgcggtgg cagcgggggt agcctgggaa
     6721 aatgcccctg caaacagcgc cactgtggcg gtaaaaatca atgtctgatc tgtttacgcg
     6781 aatgtgttgc cggatggacg tggcgaccgt tcgggtgatg ggcaaacagg cggagattaa
     6841 cggcgtcgtg tacgacgtga tgccggagga agagtccgcg gagatggggg cgctttcggg
     6901 cagccagttg tcactggtgg tgttttcagc ccggtaccgt ccggcccgtc atgatgttgt
     6961 tgtgtttgcg gggcgcacac tgacggtgac ccgttatgac acgtacaacg gtaaaccccg
     7021 gatttttgtc gaacaggaat gagtatggca ataaaaggtc tggcgcaggc catgaaaaat
     7081 ctggatgcaa ttgatcgccg tgccgttccc cgggcctctg ccacgacact gaaccgagtg
     7141 gcgggggcca ttattgcgaa aacggcctct tcagttgcca gggagctggc cgttccccgt
     7201 cgtcttatcc gtgcccgcat ccggttaagt ccggcacgac cggataaggt ttacgcaaag
     7261 gtttacatca ataccggcaa cctgcccgcc atcaaactgg gggaggcccg cgttcgactt
     7321 tcccgcagaa aacggagaaa gaaaggacag cgtgcggccc tgaaaggggg cggcagtgtg
     7381 ctgattgtgg ggaaaagacg gatcccggac gcctttatca cccggctggc taacggacgc
     7441 tggcatgtga tgcagcgtat gccgtgggca tcatcatcca ccggcgcgga cagcaaaggg
     7501 aggccgaaac gccaccgtct gccgatcgaa gtggtgaaga ttacgactgc cggaccgctg
     7561 gcagaaacct ttgaacgtga acgggaccgg atgtaccggg aaaaattacc ggcgcagatg
     7621 atgaaagcca tgacgcatca gttacgcctg gtgctgaaaa gaaaatgact gggagggtgt
     7681 atgaaacacc gtgaaatacg ggcggcagtt ctgtctgccc tgaaagaaaa tatttctgag
     7741 agggtgagct ggtttgacgg tcgcccggtt tttattgatg aacaggaact gcctgctgtt
     7801 gctgtttacc tgacagatgc gtctgctgct gacgagttcg ttgatgaggg aacctgggag
     7861 gcgacactgc atattgaggt ttttctcagg gcaaaagaac cggactcggc actggatatg
     7921 tggatggaag aaaaaattct tcctgcgctg gaggcagttc ccgggctcag tgcattactg
     7981 ctgaagatga atcttcaggg gtatgactac cgccgggatg atgagtttat gatgtgggga
     8041 tcggcagatc tcctgtggaa aattacctac gagatgtgag gacgatatgg caacaccaaa
     8101 tccccttgag ccggtaaaag gtgccggtac cactctgtgg gtttacaacg gcaagggtga
     8161 tgcttatgca aacccgttgt cagacgatga ctggcagcga ctggctaagg tgaaggatct
     8221 gacgccgggc gagatgacgg cagaacccta cgatgataac tacctggatg atgaagacgc
     8281 ggactggacc gcgaccgggc aggggcagaa gtctgcagga gataccagtt ttacgctggc
     8341 ctggaaaccg ggagaagaag gtcagaaagg gcttataggc tggtttgaaa gcggggatgt
     8401 gcgggcctat aaaatccgtt tcccaaatgg cacggtggat gtgttccgtg gctgggtcag
     8461 cagtatcggt aaggccgtga cggcgaaaga agtgatcacc cgcacggtga aagtcactaa
     8521 cgtgggcaaa ccttccgtgg cggaagaacg cagcgaaatt acgccggcca ctgcaattaa
     8581 ggtgacaccg acatccggta cggtggcaaa agggaaaaca accaccctga cggtttcttt
     8641 tgagccggaa agtgcaaccg acaagacgtt cagagcggtt tccgccgatc cgtcgaaagc
     8701 caccattagt gtgaaagata tgacaattac ggtaaacggc gtggcgacag gtaaggtgca
     8761 gatccctgtg gtgagcggaa atggtcagtt cgccgcagtg gctgaagtca ccgttactga
     8821 agcgggcgct gcagggtaaa cggaggtaat acatgtttct gaaaacagaa caatttgaat
     8881 ataacggtgt gtccgtcacg ctttccgaat tgtctgcgct gcagcggttt gattatataa
     8941 agtttgtttc agacgcagaa caacaggaga caacgaagca tgatgtcgtg cacattaacc
     9001 agcgatatct ggaaacggca tccctgcttg tggcgatgtc gctatggcat tcccattccc
     9061 tcaaaggcac tctggcctct ccggagacag agatgcagca gatccgccgt gaagtgatgc
     9121 tgggatggcc tgctgatgca ctgaatcagg caacgaaccg ggtgctttat ctttcaggta
     9181 tgctggataa ccggcacgat gccgatcctg aaccaaccgg gaaaacagaa gcgactgagc
     9241 cggtaacatc aaaaaagcat tcgaaggcga gctgaacttt gtcctgaaac tggcgcgtga
     9301 gatggggaga gccgactggc gcgccatgct tgccgggatg acatccaccg aatatgccga
     9361 ctggcgacgt ttttactgca cgcattattt tcaggatacc cagctggata tgcatttttc
     9421 cgggctgatg tacgccgtac tcagcctgtt tttttgcgat ccggatatgc atccggcgga
     9481 tttcagcctg ttcgctccgg aggcagagga aggacaggcg gagacgccgg acgaaaatga
     9541 tgtactgatg cagaaggcgg cgggcctcgc cggtggagtc cgtttcgggg aggagggaag
     9601 gaggttgtga cagttattga tggtatcaga ggacatttca ggaggtgacc acgatggcag
     9661 gtaattttgc cgatctgaca gccgtgctga cactggattc tgcccgtttt tctgaagagg
     9721 cagcgcgggt aaaaaaagag ctgggtgaaa ccagtgcgct tgctgatttg atgtccggga
     9781 aagtcagtca gtctttcaga aaacaggctg atgctgctga gcagagtctg agccgacagg
     9841 cgctggctgc acaaaaagcc gggatatcag tcggacagta taaggctgcc atgcgcacac
     9901 tgcccgcaca gttcacggat attgtcactc agcttgccgg tggtcagaat cccttcctta
     9961 tcatgctgca gcaggggggg cagatcagcg attcattcgg tggaccgctc agcctgctta
    10021 ccctgctgaa ggaggaactt ctcgggatca gggatgcctc tgaatcatca gaggagtcgc
    10081 tgtcagatac ggcaaatgca ctggctgaaa atgcccggaa tgccggtgag ctgggacgat
    10141 ttatgtcggt ggcccgtgtg gcggcaggtg gcggggttgc cgtactggcc gcgcttgctg
    10201 ccgccgcctg gcaggcagag caggctgacc gggccttatt gcgttcactg accctgaccg
    10261 gaggggctgc tgccaccaca acggcagaat tgtggaaaat ggccggggtg atcagcgatg
    10321 aagccggtgg tggtatcaga caggcggcag aaaatctggc ccgtctggca gaaagcggga
    10381 aatataccgc cgggcagcta cggatcatgg gggaaacctc tcagagatgg ctgcagacgg
    10441 tgggggacga tgccgggaag gtggaaaaag cctttgaagg gattgcagca gatccggtga
    10501 aggcgctggc ctccctgaat cagcagtata acttcctgag cgtttcccag ttacgccata
    10561 ttgatgagct tgagcgcacg aaaggtaaac aggttgcggt gacggaggcg atgtccctgt
    10621 ttgcggatgt catgaatgca cgtctggagc aacttgataa agcggccacg ccggtggaaa
    10681 aaatctggga cgatgttaaa acctggactt ctgacgcatg ggcatggata ggtgatcata
    10741 cactgggggc actcagtctg atcactgacg tggtggccgg aaccgttgaa caagtgaagc
    10801 tgctgcttgt gcagggggat ctggcgctgg ctgaatttat tcagtcagcc tgggaaacga
    10861 caaagaatgt gcccggcgtt ggtgcgttgt ttggtgaact ggcagaagag aaccgcgtat
    10921 ttattgagaa aacaaaacgc gatgaactgg cgctgagaaa atccattgcg gaacgggatg
    10981 cgcgtatacg ccagggggaa atggggtaca tcaaccgctc gcgtgcaaca ggcgtcagca
    11041 aaggtccggg gcagcaggaa gccgtcagcc gtctggctga agagctgaca ggtaaaaagc
    11101 atacatcacc gaaaacgcgc tctgccgggg agagggaaga ggagcaggca agagaggctc
    11161 tgcttgccct tgaagctgag ctcaggacgc tggaaaaaca cagcggtgcg aatgagaaaa
    11221 tcagccggca gcgccgtgat ttatggaagg cggaaagtca gtatgcggtc ctgaaagagg
    11281 ctgccacgaa acgacagtta tctgagcagg aaaaatccct gctggcgcat aaagacgaga
    11341 cgctggagta caaacgccag ctggctgagc tgggcgacaa ggttgaatac cagaaacgcc
    11401 tgaatgagct ggcacagcag gcggtgcggt ttgaagagca gcagagcgcg aagcaggccg
    11461 ccatcagcgc aaaagcccgc ggtctcactg accgtcaggc gcagcgggag tctgaagcgc
    11521 agcgtcttcg ggacgtgtac ggtgataatc cggctgcgct ggcgaaggcc acatcggcac
    11581 tgaagaacac caggtctgcg gaggagcagc ttcgtggaag ctggatggcc gggctgaagt
    11641 ccggctgggg cgagtgggcg gaaagtgcga cggacagttt ttcgcaggtt aaaagtgctg
    11701 ccacgcagac ctttgacggt attgcacaga atatggcggc gatgctgacc ggtgcagagg
    11761 cagactggcg gggattcacc cgttcggtgc tgtccatgat gacagaaatc ctgcttaaac
    11821 aggccatggt gggcattgtc gggcgtatcg gcagcgccat tggcggtgct ttcggtggtg
    11881 gtgcatctgc ttcctcgggg acggccattc aggctgcggc ggcgaacttc catttcgcga
    11941 ccggaggatt tacggggacg ggcggcaaat atgagcctgc ggggatagtt caccgcgggg
    12001 agtttgtttt cacgaaagag gcaaccagcc ggataggtgt ggggaatctt taccgtctga
    12061 tgcgcggcta tgcggaaggt ggttatgtgg gtggtgccgg aagtccggcg cagatgcggc
    12121 gggcggaagg tattaatttt aatcagaaca atcacgtggt gattcagaac gacggcacca
    12181 acggacaggc ggggccgcag ctgatgaagg cggtgtatga catggcccgc aagggggcgc
    12241 aggatgagct ccggctgcag ttgcgtgatg gcggtatgtt atcggggagc gggcgatgaa
    12301 aac
//
LOCUS       DAZUDJ010000107        12195 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.107, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000107 DAZUDJ010000000
VERSION     DAZUDJ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12195
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.107"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..658)
                     /locus_tag="ACHY1N_004478"
     CDS             complement(<1..658)
                     /locus_tag="ACHY1N_004478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046665.1"
                     /translation="MYDFITIMYDVFSCFGVLAKNQNTRDIRNIKNFSSHQYSLGDMF
                     DELINIIDKEQVLSTEQRKVIFRRYEDLYVKLMHYSVFTDKTHQIIKQKYFNDIVPMI
                     LALDIRNTYRPDNEMAFYYHIHSFLTQIPDNEDDIYHAARTYLRNYVKLCLSGYTPAN
                     AHFKDIFDGVYEFIRNIRKNSTPGKTKLIATINTCKETCKHLLYLSNEDKEKIISDLD
                     K"
     gene            855..1548
                     /locus_tag="ACHY1N_004479"
                     /pseudo
     CDS             855..1548
                     /locus_tag="ACHY1N_004479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            1771..2067
                     /locus_tag="ACHY1N_004480"
     CDS             1771..2067
                     /locus_tag="ACHY1N_004480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4046666.1"
                     /translation="MPDQSGYCWTPSRILRMPELSQLLGISRSTIYEKMNPLSKYYDA
                     TFPRPVRLGSGSVGWRSSAIDEWLTLHTVPARSAVKGVNDEVRHTLSSDMTMSR"
     gene            2375..2491
                     /locus_tag="ACHY1N_004481"
     CDS             2375..2491
                     /locus_tag="ACHY1N_004481"
                     /inference="COORDINATES: protein motif:HMM:NF024547.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046667.1"
                     /translation="MSIACQNQVDVCSPGNLRGAVNIYTMVLEKGKRPGERY"
     gene            2710..4143
                     /locus_tag="ACHY1N_004482"
     CDS             2710..4143
                     /locus_tag="ACHY1N_004482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfjI family protein"
                     /protein_id="HFS4046668.1"
                     /translation="MCLLAPENPYPIYALPPLVRNAIIETQKNTQAPLAMVATSALTA
                     FSSACQNQIDVCRPGNLRGPVNLYSLILADSGERKTTVDKVFMKAFYLRDEALAEEYA
                     KLVENYSTEKEIWEQKQKALESKLHKEIRAGKDCKATESELKRHLNKCPVPPQIRRTI
                     FNETTIEGMLKYYSDSNRSFALVSSEGGIIFDGRAMSKLGILNSLWDGGSLFIDRKSS
                     PGIILKDPRLTVSVMIQPDVYQKGFCTRKKELVKTSGHHARFLMCQPTSTQGTRIITG
                     DNYSSQYQDLFEQRINELIDENLAMSGERRCLHFSPQAARIWTDYYNDVESKLGGLGP
                     LRHCREYAAKNAEYMARLAGLIHHSSGEEGDISPYTAEMARELAIWYGNEYVRLSNPL
                     TFDNPALTVPVRLIPEELELFNWIKSYCIEKGIPCMKKNDILQRGPNRFRKKDKINWL
                     LDLLYEQNRVVPVIEGKTLCVAPNFDL"
     gene            5118..5681
                     /locus_tag="ACHY1N_004483"
     CDS             5118..5681
                     /locus_tag="ACHY1N_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HFS4046669.1"
                     /translation="MYNANPNYEMDFMILKDVNEHMEGLFQRFSKLLPFRIDFAYRKD
                     TPSFGHGCKHSMCMEIYRLLSETQSMLAGYYWVMEYTQNKGLHIHFVGYLDGQRHKNS
                     YQISRQLGDIWRQITEGEGYFHLCRAKDKYPVRIDHVMHYSDKSAVDNLRYALSYLAK
                     QDQKEHGIILGRSRLPEKSNRGRPRHN"
     gene            complement(5986..8406)
                     /locus_tag="ACHY1N_004484"
     CDS             complement(5986..8406)
                     /locus_tag="ACHY1N_004484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-loop NTPase fold protein"
                     /protein_id="HFS4046670.1"
                     /translation="MYFPLIHYGIIYCDTLLSHPQKHLPKRKLTAGQSFADLAWKQYH
                     VTDTAQHRLHLRRFVNMNQPHADNLQGQHPDRAICSADEDQYGFIHIATQLAVAVKGI
                     GREGSAVIGIEGPWGSGKTSLLNLLRNALVEQIEERTFVLTISPWLDGSNTSLVASLL
                     LPVANIIAAEEEQRLAPEERTALRRRKSLTRTAKTMIDYTRATARNLAPVASAAAVIP
                     GVPDASGALKALSETRWLKEKEKTTAEMRTEIAKKIDELDLSFIVLLDDLDRLEPAQA
                     VEVIRLVKSVGDFPRFRYLLCYDKAILSQAISLGLGVPDGNLYLQKIVQISFCLPRPE
                     TFVLRRKFRDAAAALYRKVNGHAPDRIVLEQLTQVADVYGAALKTPREVQMVLNALTF
                     LYPGMRDYVYFPDLCFLQLLRTTNAGLYDWVEEYLSERAVVAAGDGHVSELEQAEMAE
                     SLKSHLARYFPAEAHAVHALARWVPGITGWKTDSPIKLFVPTPEQDSALLTAGKRLGS
                     QAYWRYYFAFSAPQNVLSPEMLNEIFDIAGYPEQQHKLAERLLGYIQSKGLSSRTWFE
                     HILTQLTTQQIATRTPEQCRGLAQFFFDSGDKMLQRYQDENDWFSIHDLDTWSVTDRL
                     INKIQKESDQESFDFLSTQFKNGQAWYWIAEYMRHLLWQHGRVGDRAVHEQQKWIPSF
                     QLDSLCETLAHRLNGKVITDQLASFPQLNGYIWAWRDISGVEAVRTWVQEQIRDDEAF
                     LKLLLQLCYHGISSAEGRFTALKLSDLADFFGEPDQIRERIENIRKAGPLAEMAKQVE
                     TSIKRNRF"
     gene            complement(8632..9378)
                     /locus_tag="ACHY1N_004485"
                     /pseudo
     CDS             complement(8632..9378)
                     /locus_tag="ACHY1N_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9569..9785
                     /locus_tag="ACHY1N_004486"
                     /pseudo
     CDS             9569..9785
                     /locus_tag="ACHY1N_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309332.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9813..10553)
                     /locus_tag="ACHY1N_004487"
     CDS             complement(9813..10553)
                     /locus_tag="ACHY1N_004487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HFS4046671.1"
                     /translation="MNRNDSVYVAWQAPDTHDWHVVGNLQARNAEYVFNYTKGALTSP
                     KFIKFSGMNDFNETYVSEELFPLFKNRLLSPKRPEYPKFIHWLGLDGTEAEPIEILAR
                     SGGMRSTDQLQMFKRIEIDSDGYFEHFFFAHGLSYMPHSANERVSHLNPGDKLFLCPD
                     VQNDYDKAAVLIRTDSPPEIVGYCPRYFASDIKRMLLDNDDSISLSVERISADAPHNY
                     RLLCKATGKVSKTFIDQMILQEEFQPVV"
     gene            complement(10543..11472)
                     /locus_tag="ACHY1N_004488"
     CDS             complement(10543..11472)
                     /locus_tag="ACHY1N_004488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046672.1"
                     /translation="MAQYRLERLAPVASDLEQLGTKEKFWFSMDTEPKLWLFKFSRAG
                     TGEHWSEKCAAELCHLLGIPHAEYELALIDGRYGVISPNMIPPGYRMVMGNEVLHTTT
                     MGYPQPLPPGQSAVRVKEHTVTRVLGCLDNDHEKIHPPVSGYDLKDLNAGDVFCGYLL
                     LDALISNQDRHHENWAIMLNNETGERMLCPTYDHAASLGREMRDVEKAERLTTKDRNR
                     QIPAFVKRARSELFKLKTDKKPLLTVEAFRHAIENRPRAKEYWFGRLNTLTHEDIVGV
                     FNNVPADCISEVSRTFAIEMVLENRRRLLEDES"
     gene            11614..11817
                     /locus_tag="ACHY1N_004489"
     CDS             11614..11817
                     /locus_tag="ACHY1N_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046673.1"
                     /translation="MTFVSVVRGRLTGQEDNRSWLAEAVTRKLWDSFYINYINISWAA
                     LNTAYKDLCFSFPLHKPQLRSHF"
     gene            11933..>12195
                     /locus_tag="ACHY1N_004490"
     CDS             11933..>12195
                     /locus_tag="ACHY1N_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HFS4046674.1"
                     /translation="MQYRQENILTKASRLPHTLSISCYFVFRCVSPLVCYLSVFSVFF
                     IPAFSSPAAMLSPGDRSAIQQQQQQLLDENQRQRDALERSAPLT"
BASE COUNT         3323 a         2596 c         2731 g         3545 t
ORIGIN      
        1 ttttatctaa gtcagaaatt attttttcct tgtcttcatt acttaaataa agcagatgtt
       61 tacaggtttc tttgcatgtg ttgatagttg cgataagttt tgtttttcct ggtgtactgt
      121 ttttgcgaat attacgaatg aattcatata cgccatcaaa gatatctttg aaatgcgcat
      181 tcgctggtgt gtatccggat aaacataact taacgtaatt tcgcagatat gtccttgcag
      241 catgatatat atcatcctca ttatccggta tctgagtgag aaaagaatga atatgatagt
      301 aaaatgccat ctcattatcc gggcgatatg tgttcctgat gtcgagtgcg agaatcattg
      361 gtacaatgtc attaaaatat ttttgtttta ttatttgatg tgttttgtct gtaaaaacag
      421 aatagtgcat tagcttaaca tagagatctt catatctcct aaatataact tttcgttgtt
      481 ctgtactcaa tacttgttct ttatcaataa tgtttattaa ttcatcaaac atgtcgccca
      541 gtgaatattg atgtgaggaa aaatttttaa tatttcggat gtcacgggta ttctggtttt
      601 tagccagaac accaaaacat gaaaagacat catacattat agtgataaaa tcatacataa
      661 cattctcctt ttattgcact atataaaatt ttaacattat atcattttgc ttttctgtta
      721 actggttttc atttttgaat caatattttc tgaacagggt aatagaacac gtattaacag
      781 attatgtcag aaggccccgg tgatgccttc tgacgataga ttaatgtggt attctattgg
      841 tatctggaga ccatatggca acagttacag tacattctcc ccgctgtaat tcctataaag
      901 tgtaccatta tgatcacagc acctcagatc atgagcgttt ccagtgctaa tcctgcaaac
      961 gtgtgtattt taactgcatt acatctacga aacccgaaaa ccaggcatta aagagcaaat
     1021 tgttgaaatg gttcataacg gagtcggggt tcgcgatagc tccagaacgc tgaaggtgga
     1081 tatcaacacc gtcattctca ctttataaaa cgctcaccac gcaaagtaac cacatctcca
     1141 gtcgccagtg ccgatgtgac gcttatctgc gaacttgatg aacaatggag ttttgtcgaa
     1201 aataaagctc gtcagcagtg gcactggtat gcgtataaca ccaaatctgg aggtgtgctg
     1261 gcttacactt ttggtcctcg cactgatgaa acatgtcgtg agttgccgga actcctgaag
     1321 ccattctcca caggcatgat aaccagagac aaccggagca gttataccag agaaatgcca
     1381 caggataagc atcttgtcgg caagatattt acccggcgca ttgagcgcaa caatctgaca
     1441 cttcgtactc acatcaaacg accagcccgg aaaacgattt gcttttcacg ctccctggaa
     1501 attcacgaaa agccattggt tcatttgtcg aaaacactgt actactgact ggagtcatta
     1561 ccagggcctc ttttgctgtt ttttaccaat gaatgataat gagaatcgac agcgataagg
     1621 tgaaagtaaa ataacaataa tgctgttgtt ttctatcgta ttgattttta attatttatt
     1681 gtctttttgc tcagcccatt tttttacgca gacaaattta cccggggaat acaaactgta
     1741 acgacagttc accacactat gggggataaa atgccagatc aatccggata ctgctggact
     1801 ccttcacgca tcttacggat gcctgaactg agccaattgt taggtatatc tcgttcgaca
     1861 atttacgaaa aaatgaatcc gttatcgaaa tactacgatg caaccttccc caggccggta
     1921 cgtcttggta gtggttctgt gggatggcgt tcatcagcta ttgacgaatg gcttacttta
     1981 catactgtac ctgccagatc agcagtcaaa ggtgttaatg acgaagtgcg acatacgctt
     2041 tcttcagata tgaccatgag cagataagtt tttgtcatca cgtgatcacc tcaggaggaa
     2101 aaagaagcat aagaacaatt tagccagaag tttaattgat aaacagaatt tccagcattc
     2161 attgttgaaa gagcagctat tgtcgctatt gtagcggtaa ttgctgctat aaccgaaacg
     2221 tattacgaaa aaggaagcat ttatgtctta catcaaaccg gatatgccgt attcagtata
     2281 tgcgtgacca tcaatgatag ggaaggcaat aattaaagct caatacaata aacaagtacc
     2341 tctgactctg gttgcaatgt cagtattaac agcgatgtca attgcctgtc agaatcaggt
     2401 tgacgtatgc agccccggaa atttacgtgg ggccgttaat atttacacta tggttctgga
     2461 gaaagggaaa agaccggggg aaaggtatta gtgaaataat ttcaggaggt attaagaatg
     2521 agaaatatga atgatgtttc gtggtaaata atacagtctg cactgaatta accttatcgg
     2581 tttattaaac atcagatcta caaatgctct gtatttctca gagcatcagg tctgaatagc
     2641 agctattttc gctattgtag cgggatttgc tgctatttta ctaacccatt actgaaaaga
     2701 gaggctttta tgtgcttact tgcaccagaa aatccttatc cgatatatgc actaccaccg
     2761 ctggtgagaa atgcaataat tgaaactcaa aaaaatacac aggcaccttt ggctatggtg
     2821 gcgacatccg cattaacagc gttctcaagt gcctgtcaga atcagattga cgtgtgcaga
     2881 cctggaaatt tacgtgggcc tgttaatctt tactctctga ttctggctga ttccggtgaa
     2941 aggaaaacga ccgtggataa agtgtttatg aaagcatttt atctcaggga tgaagccctg
     3001 gcggaagaat acgcgaaact ggttgagaat tacagtacag aaaaggaaat atgggagcaa
     3061 aagcaaaaag cactggagtc aaaattgcat aaagaaattc gcgccggtaa agattgtaag
     3121 gcaacagagt cagagcttaa aagacatctg aataaatgtc ctgttccgcc gcagatacgc
     3181 cggacaattt tcaatgagac aacgatagag ggaatgttaa aatattattc cgacagcaat
     3241 cgctcttttg ctcttgtatc cagtgaagga ggaataattt ttgatggccg ggcaatgagt
     3301 aaacttggaa tacttaactc tttgtgggat ggtggttctc ttttcatcga caggaaatca
     3361 tctcccggaa ttattttgaa ggatccaaga ctgacggtat cggtgatgat tcagcctgat
     3421 gtttaccaga aaggtttttg tacgcgaaaa aaagaacttg tgaaaacgtc aggacatcat
     3481 gcaaggtttt tgatgtgtca accaacatca acgcagggga caaggataat aaccggagat
     3541 aattattcat cacagtatca ggatttgttt gaacagagga tcaatgagct tattgatgaa
     3601 aatctggcga tgagtggtga acgacgttgc cttcactttt ctcctcaggc tgccagaatc
     3661 tggacggatt attacaacga tgtggaatcg aagctggggg gattggggcc tttaagacat
     3721 tgccgggaat atgctgctaa aaatgcagag tatatggcaa gactggcagg acttattcac
     3781 cattcgagcg gtgaagaggg ggacatttcc ccttacactg cagaaatggc gagagaatta
     3841 gcaatatggt acggtaatga gtatgtgcgg ttgtctaatc cgttaacttt tgacaaccct
     3901 gccctgaccg tacctgtgcg actcattcca gaggagcttg aacttttcaa ctggataaaa
     3961 agctattgca ttgagaaggg gatcccctgt atgaaaaaaa atgatatttt acagcgtggt
     4021 ccgaaccgtt tccggaaaaa ggataaaatc aactggttac tggatttact gtatgaacaa
     4081 aacagagttg taccggttat tgagggaaaa acgttgtgtg tcgcacctaa ctttgacctc
     4141 tgaacgactt aatcgttgag taacatatag tctcctctgc tacttgcgga ggagactaat
     4201 gcctttacca cgtcagcgtt gttgtattag aaaactctgg tacaggtcag tcagtaaata
     4261 taactggtgt aaccactatt tactattgga tagagtgttg ctcaggatat tgtcggcttt
     4321 agtctgaggt gaggtgggac cttcattgtt ttcgtgttca ataaataatt taggttaatt
     4381 agtattatta atgggagtta tgttatctgt tatgttatct tatctctctc tttctatcgt
     4441 aatatcactc ctctttatgc taagtattct gtatgtgcgt aatgcatata tctccataca
     4501 ctacagtgtg gtggtgtatg gagtttagtt atgtgtaaat tatgttacta cacttatagc
     4561 gtaatattga gaaagttaat ccactgaatg tatgtctggt ttgtatttaa cactagttac
     4621 gtaccagaac actattagag tatattgtct ttagttcgta cgttatagct ccgttacagt
     4681 ttatgggtaa atataatctt ttctgtatga aataatcttc ttattgtgag attaaatatc
     4741 tgtaggctct ctctgcagag tctctgtttt tacttaatgg tacggcaata ctaatagcga
     4801 tgttgcctgt ggctattcaa tgctgacttt tgtgaagatc agattatttc ctgtaagtaa
     4861 ttgaatggtg ctttcttaaa ctcaattata tgaggtgtgt tttttattgt aattcgttct
     4921 ggtcctcagt ttaagagagt cttactgtat tctgaatcat taccctatta ctgtaatgag
     4981 gtaataccaa acagttttat caggttgtct gtgctgctgg ttacctcgtt tattaatgcc
     5041 gtggtacgac gtttctgtat cctcagcatt tacgtaattt cctcttcctg tgagttttat
     5101 aaagtaagga ctataaaatg tataatgcta atcccaatta cgaaatggat ttcatgattc
     5161 tgaaagacgt gaatgaacac atggaaggtc tgtttcaacg tttttctaaa ctgttacctt
     5221 tcagaattga ttttgcctac aggaaagaca cgcccagttt tggtcatggc tgtaagcaca
     5281 gtatgtgtat ggaaatatac cgcttactta gcgaaaccca atcgatgttg gcgggatatt
     5341 actgggtaat ggaatataca caaaacaaag ggcttcatat tcattttgtc ggctacctgg
     5401 atgggcaacg tcacaagaac tcttatcaga tatccaggca actgggagat atctggaggc
     5461 agatcacgga aggggagggt tactttcacc tttgccgggc taaagacaaa tacccggtgc
     5521 gtatcgatca cgtgatgcac tatagtgata agtccgcggt agacaactta cgttacgccc
     5581 ttagctatct ggctaaacag gatcagaaag aacacggtat tattctgggc cgtagcaggc
     5641 ttcccgaaaa aagcaaccgg ggccgaccac gacacaactg aattacagct gtattaggta
     5701 ttagaattaa gtttctgtaa gttgttggga ggtgccggag ttaatatgct gcaaggttcg
     5761 ggggctttgt catcagtgta ggggcgcgaa tttctgtcgt ggtgcctcag tggatcggat
     5821 acaggtaacg atgtcaacgc catgatgttt gactgtctta tatcattggc gctgacagag
     5881 gtcaccggaa cattacgtaa ctcccactag acagtggtaa acaacggcac caataagctg
     5941 gttgcgacct tactcattga tgctcactac caagaggggc ataatctaaa acctatttcg
     6001 tttaatcgac gtctcaacct gcttagccat ttcagccagt gggcctgctt tcctgatgtt
     6061 ttcaatgcgt tctctgatct ggtctggttc cccgaaaaag tcagctaggt cactcagttt
     6121 cagggcggtg aaacgtcctt ctgcagagct gattccgtga taacacaatt gtaacagtag
     6181 tttcaaaaag gcttcatcat cccggatttg ttcctgaacc caggtcctaa ctgcttcaac
     6241 gccactgata tcacgccatg cccagatata accgtttaac tgagggaaac tggctagttg
     6301 gtcggtgatc actttcccat tcagacgatg tgccagagtt tcacataagg agtcgagttg
     6361 aaaagatggt atccactttt gctgctcatg tactgctctg tctccaactc ttccgtgctg
     6421 ccacagcaga tgacgcatat attctgctat ccagtaccag gcctgaccgt ttttaaactg
     6481 cgtggacagg aagtcgaaag attcttgatc gctttccttt tgtatcttat tgatgaggcg
     6541 gtccgtcacg ctccaggtgt ctaggtcatg tatagaaaac cagtcattct cgtcttggta
     6601 gcgttgcaac attttatctc cggaatcaaa gaagaactgc gccagtccac ggcattgctc
     6661 tggtgtcctt gttgcaatct gttgtgtggt gagctgggtc agaatgtgtt caaaccaggt
     6721 tcgggaggac aaacccttac tctggatata cccgagtaga cgttctgcaa gcttatgttg
     6781 ttgttcagga tatccggcga tgtcgaatat ctcattgagc atttcaggtg aaagtacatt
     6841 ctgtggggcg gaaaaagcga aataatagcg ccagtatgct tggctgccca gacgtttgcc
     6901 agcagtcagc agggcactat cctgttcggg agtcggtaca aagagtttga tgggcgagtc
     6961 agttttccag ccggtgatac ccgggaccca gcgagcaagg gcatgcaccg catgggcttc
     7021 ggcagggaaa taacgggcaa ggtgcgactt taggctctcc gccatctctg cctgctctaa
     7081 ctcacttaca tgcccgtcac cggcggctac gaccgctcgt tctgacagat attcttctac
     7141 ccagtcataa agacccgcat ttgttgtgcg cagcagttga aggaagcaca gatccgggaa
     7201 atacacgtaa tcccgcatgc ccgggtatag gaaggtcagg gcattcagta ccatctgaac
     7261 ctccctgggg gtttttaatg ctgccccgta gacgtcagcc acttgtgtca attgctctag
     7321 tacaatacgg tctggagcat gcccgtttac ttttctgtat aacgcggcag cggcatccct
     7381 aaattttctg cgcaagacaa aggtttctgg gcgcggtaaa cagaatgata tctgaacaat
     7441 tttctgcagg tataggttgc cgtcgggtac ccccagccct aggctgatgg cctgggatag
     7501 gatggctttg tcataacaga gaaggtagcg aaagcgagga aagtcaccta cagatttaac
     7561 tagccttatc acctcaactg cctgtgctgg ctcgagacga tccagatcat cgagcagtac
     7621 aataaagcta agatccagtt catctatttt cttcgcaatt tcggtccgca tctctgctgt
     7681 ggttttctcc ttttccttca gccaacgagt ttctgacagg gctttcaacg cgccactggc
     7741 atcaggtacg ccgggaataa cggcggcggc tgaggcgacg ggtgcgagat tgcgggcagt
     7801 tgcccgggtg tagtctatca tcgtcttggc cgtccgtgtc agggattttc gtcgtctgag
     7861 agctgtcctt tcctcaggcg ctagtcgctg ttcctcttca gcagcaatga tgttggcgac
     7921 aggaagcagt aacgatgcca ccagacttgt gttgctcccg tcgagccagg gggatattgt
     7981 caatacaaaa gtgcgttctt ctatttgttc gacgagagca ttgcgcagca ggttaaggag
     8041 actcgttttc cctgatcccc atgggccttc gataccgatc actgcgctac cctcgcggcc
     8101 aataccctta acggcaacag ctaactgggt agctatgtgg atgaaaccat actggtcttc
     8161 atcggcggaa cagattgcgc gatctggatg ttggccctga aggttgtctg cgtgtggttg
     8221 attcatattc acaaatctcc gtaaatgcag ccgatgctgc gcagtgtctg tgacgtggta
     8281 ctgtttccac gcaaggtcag caaaagactg acctgcggtt agtttgcgtt taggtaagtg
     8341 cttttgcgga tggctcagta acgtatcaca ataaataatg ccatagtgta tgaggggaaa
     8401 gtacatacat cttgttccct cttcgaaagt gacggcccgg gataaagagg ttacaacgat
     8461 aagggtctcc cgccgaaatg atgaatgctt atggctgggg aaagctaaga gtatgctgga
     8521 cgcttagaaa actgctaaaa ctgtgaacct tgataagttt gtccccgcgc cagattactt
     8581 cctttcgagg ttgcagtatt atcggtgaaa ttgtggtacc cgagagtagc tcattcgttc
     8641 aagcgcatcg ccaatatttt ttagcaggtg ccatcgatcg accacctgtc tggcctgagg
     8701 tgcaccttca cgtgctgctg tcgcatagac tccattgcga tcacgcgaga caacctgtat
     8761 ttccggatat tttctgaacc aggtcgccag cgtacgctga tcgcggtcgg gaaacaggac
     8821 gaggggacgg tgagtatcaa gattgactat taacgtaccg taacggtggc cccgatgcca
     8881 cgcccactca tcaataccga catgggatga gcctgacagt ttcgtctctg gggtattgat
     8941 aaccctgcga agaagagtat ctgcactaca acggagaccc actgccgtta ccacccgttt
     9001 cccggcctca cttccggcta ttaatcccag ttaacgttgt aaattttgta acgcctgtga
     9061 agactgctgg tgtgaaccgg cgaagggggc aagcgacccg gcaaaaattt ttcgtgaaca
     9121 agcagggtta cggcagtacc tgtggcggac ggaaaataca agccatagtg tctgccctga
     9181 gcagggtaaa tgctgtatcc ggcgctgacg acaactatga acagagtcgc tgcatttaag
     9241 gcattcaggg cattgtgctg ttttgcgttt tccgcggaga tggagggtta taccgtcaga
     9301 gctaataatt tgtcggctgc atcgccatcc gcaaggtaac tgtagaagtg tcttaagaga
     9361 gtgcattacg ttgcccataa cttaaaacag cttagatcct tgttcaccag aaagtttcat
     9421 ccattttctt ccacccaggt tgcggaagag ccacttttca tccgtcgttg acagaatggc
     9481 cctccaaccg tgtttgacga actcttgcca tggaacgtag tactcaccaa taaataagcg
     9541 tcaatacggt gccccgttga cgcttaccaa tattgctgaa gaaataatcg ataaacgatt
     9601 tgttggtacg gaatgtaatg tggttttcac gggaaacctc agagaggagc aggaagaggc
     9661 cgcttcggta ttaccctgct atgatactgg tgtgctttgt gcgcgttacg gcttctggta
     9721 agttaccgca gcggcagtga tcgccagacg cacttatacg ggtacaccgg actgagttgt
     9781 tgaaagcctg aataatcctc caggctttac atttacacaa ctggttggaa ttcttcctgg
     9841 agaatcatct gatcaatgaa agttttcgac actttcccgg ttgctttaca aagaagcctg
     9901 taattatgag gggcatcggc actgatacgt tcgacactta aactaataga atcatcgtta
     9961 tcaagaagca ttctcttgat atcactggca aaataacgag gacagtaccc tacaatttct
    10021 ggtgggctat ctgttcgaat gagcacagca gctttatcat agtcattctg cacatccggg
    10081 cacaggaaca gtttatctcc cggattcagg tgagatacgc gttcattagc ggaatggggc
    10141 atatagctta atccgtgcgc aaaaaagaaa tgttcaaaat atccgtcact atcaatttcg
    10201 atgcgcttaa acatttgcaa ttggtcagtg ctacgcatac cgccagagcg agcaaggatc
    10261 tcaattggtt ccgcctctgt tccatccaat cctagccaat gaatgaattt tggatactca
    10321 ggtcgttttg gcgacagaag cctgtttttg aataatggga ataattcctc agaaacataa
    10381 gtttcgttaa aatcattcat accactaaac ttgatgaatt ttggagaagt taaagcacct
    10441 ttagtatagt tgaagacata ttcagcatta cgtgcctgta aattccccac gacatgccag
    10501 tcatgggtat ctggagcctg ccatgcaaca tatacggagt cattacgatt catcttcaag
    10561 caaccttctt ctgttttcta aaaccatttc aatcgcaaaa gttcgagaca cttcactaat
    10621 gcaatccgct ggtacgttat tgaatacgcc aacaatatcc tcgtgagtta acgtgtttaa
    10681 tcgaccgaac caatactctt ttgctcttgg tctgttttct atagcatgtc tgaacgcttc
    10741 aactgttaac agaggtttct tgtctgtttt aagtttaaag agctctgaac gtgctctttt
    10801 cacaaaagca gggatttgcc gattacgatc tttagttgta agacgttcag ccttttcaac
    10861 atctcgcatt tcacggccaa ggctggcagc atgatcatat gttgggcaca acattctttc
    10921 accagtttca ttgtttagca taattgccca attttcatga tgacgatctt gattgctgat
    10981 taatgcatca agcagcaagt aaccgcaaaa aacatctcct gcgtttaaat cttttaaatc
    11041 atagccactt acaggtggat ggattttctc gtgatcatta tcaagacatc ctaatacacg
    11101 agtaacagta tgttccttaa ccctcacggc actttgacca ggcggtaatg gctggggata
    11161 acccattgtg gtagtgtgaa gaacctcgtt tcccataacc atgcggtatc cgggagggat
    11221 catattaggt gaaatcacac cgtaacgccc atcaattaga gctaattcgt attctgcatg
    11281 agggattccc agtagatggc aaagctcagc cgcacatttt tcagaccaat gttcgcctgt
    11341 cccagccctt gagaacttga aaagccacaa tttaggttcc gtatccatag aaaaccagaa
    11401 tttttctttc gtcccgagtt gctcaagatc actggctaca ggagctagac gttctaaccg
    11461 atattgagcc attaatcttc cttgtatgag atacaaaaat ttgaatcatt ctactctggg
    11521 ttacgccata acgtgttata aataatatca ccatactgtg attatatcca gttaatcact
    11581 atctgttatt atggtaagta ttaacaattt catataactt ttgtcagcgt tgtcagaggc
    11641 aggcttactg gacaagagga taaccgaagc tggctggcag aggcagttac ccgcaaattg
    11701 tgggacagct tttatataaa ctatataaac atctcttggg ctgcgctgaa cacggcatac
    11761 aaggacctct gtttttcctt ccccctccat aaaccacaac tccgatcaca tttctgacat
    11821 tttcccggat tttacactac aggattgttt cagtatgttt tttatctggt gtaaatttca
    11881 gcactgacat tccgcttacg ttaatttaca ctgaatacct cacgaggaga acatgcagta
    11941 ccggcaggaa aacattctga cgaaagcctc tcgtttaccc catactctgt ccatttcctg
    12001 ttattttgta ttccggtgcg tatctccgtt ggtatgttat ctctccgttt tttctgtttt
    12061 tttcatcccc gcattttcgt ctccggcagc catgctgtct ccgggtgacc gcagtgcaat
    12121 tcagcagcaa cagcagcagt tgctggatga aaaccagcgt cagcgtgatg cgctggagcg
    12181 cagtgcgccg ctgac
//
LOCUS       DAZUDJ010000108        12008 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.109, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000108 DAZUDJ010000000
VERSION     DAZUDJ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12008
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.109"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            152..715
                     /locus_tag="ACHY1N_004491"
     CDS             152..715
                     /locus_tag="ACHY1N_004491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4046675.1"
                     /translation="MSKFVKTAIAAAMVMGVFTSTATIAAGNNGTARFYGTIEDSVCS
                     IVPDDHKLEVDMGDIGAEKLKNNGTTTPKSFQIRLQDCVFDTQETMTTTFTGTVSSAN
                     SGNYYTIFNTDTGAAFNNVSLAIGDSLGTSYKSGMGIDQKIVKDTSTNKGKAKQTLNF
                     KAWLVGAADAPDLGNFEANTTFQITYL"
     gene            797..3439
                     /gene="yfcU"
                     /locus_tag="ACHY1N_004492"
     CDS             797..3439
                     /gene="yfcU"
                     /locus_tag="ACHY1N_004492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher protein YfcU"
                     /protein_id="HFS4046676.1"
                     /translation="MPDHSLFRLRILPWCIALAMSGSYSSVWAEDDIQFDSRFLELKG
                     DTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLAEEYDIYWYAGEDDASKSYACLTPELV
                     AQFGLKEDVANNLQWSHDAKCLKSGQLEGMEIKADLSQSALVISLPQAYLEYTYPDWD
                     PPSRWDDGISGIVADYSINAQTRHEENGGDDSNEISGNGTVGVNLGPWRMRADWQTNY
                     QHTRSNDDDEFSGDETQKKWEWSRYYAWRALPSLKAKLALGEDYLRSDIFDGFNYVGG
                     SVSTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQMGRVIYETQVPAGPFRIQDLGDSV
                     SGTLHIRIEEQNGQVQEYDISTASMPYLTRPGQVRYKIMMGRPQEWGHHVEGEFFSGA
                     EASWGIANGWSLYGGALGDENYQSAALGVGRDLSTFGAVAFDVTHSHTKLDKDTAYGK
                     GSLDGNSFRVSYSKDFDQLNSRVTFAGYRFSEENFMTMSEYLDASDSGMVRTGNDKEM
                     YTATYNQNFRDAGVSVYLNYTRHTYWDREEQTNYNIMLSHYFNMGSIRNVSISMTGYR
                     YEYDNQADKGMYISLSMPWGDNSTVSYNGNYGSGTDSSQVGYFSRVDDATHYQLNVGT
                     SDKHTSVDGYYSHDGSLAQVDLSANYHEGQYTSAGLSLQGGATLTAHGGALHRTQNMG
                     GTRLLIDADGVADVPVEGNGAAVYTNMFGKAVVSDVNNYYRNQAYIDLNKLPENAEAT
                     QSVVQATLTEGAIGYRKFAVISGQKAMAVLRLQDGSHPPFGAEVKNDNEQTVGLVDDD
                     GNVYLAGVKPGEHMSVFWSGVAHCDINLPDPLPADLFNGLLLPCQHKGNVAPVVPDDI
                     KPVIQEQTQQVTPTNPPVSVSANQ"
     gene            3459..4211
                     /locus_tag="ACHY1N_004493"
     CDS             3459..4211
                     /locus_tag="ACHY1N_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HFS4046677.1"
                     /translation="MSDLLCSAKLGATTLALLLSAASLSAQASVTPDRTRLIFNESDK
                     SISVTLRNNDPKLPYLAQSWIEDEKGNKISSPLTVLPPVQRIDSMMNGQVKVQGMPDI
                     NKLPADRESLFYFNVREIPPKSNKANTLQIALQTRIKLFWRPKALENVSMKNPWQYKV
                     TLTRNGQEFTVNNPTPYYVIFSNASTQKNGNPAAGFSPIVMSPKTSAPLNVKMGSVPV
                     LTYVNDYGARMPLFFTCNGNSCQVDEEQSRKG"
     gene            4186..4734
                     /locus_tag="ACHY1N_004494"
     CDS             4186..4734
                     /locus_tag="ACHY1N_004494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4046678.1"
                     /translation="MKSRAAKAEAGRASMKGSCSVWAVTGLLICCVGSGFAVAASKSV
                     SMNLRVLVDAPPPCTVNGAAVEFGNVFINKINGVDYKRPIDYSLVCNNLAMDDLRLQM
                     QATTVVINGETVISTGIPGFGIRVQKSSDHTILDLTSGSWLPFNFSSGVPVLEAVPVK
                     QSGTTLAAAEFNASATIVVDYQ"
     gene            4731..5201
                     /locus_tag="ACHY1N_004495"
     CDS             4731..5201
                     /locus_tag="ACHY1N_004495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4046679.1"
                     /translation="MKRISLILLWGFCSMALSNVSFHGYLVQPPNCTISNAQTIEITF
                     QDVLIDDINGSNYEQTVPYSITCDTAVRDPLMEMTLSWSGTPSDFDNAAVSSNITGLG
                     IQLKQAGQSFTINTPLVVNETDLPVLTAVPVKKSGVVLPEADFEAWATLQVDYQ"
     gene            5198..5722
                     /locus_tag="ACHY1N_004496"
     CDS             5198..5722
                     /locus_tag="ACHY1N_004496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HFS4046680.1"
                     /translation="MKKKRTLFFISSLMLLGSGTTIAGDNLHFTGNLISKSCTPVING
                     SQLAEVHFPAIAASDLMNLGQSERVPLVFQLKDCHSSTLFNVKVTLTGTEDSALPGFL
                     AFDSSSSASGAGIGIETAAGTSVPINNTTGVTLPLNQGNNSLNFNTWLQAKSGRDVTS
                     GDFSATVTATFEYF"
     gene            5709..6581
                     /locus_tag="ACHY1N_004497"
     CDS             5709..6581
                     /locus_tag="ACHY1N_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001397279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="StfH/YfcO family fimbrial adhesin"
                     /protein_id="HFS4046681.1"
                     /translation="MSISEMKKWTIIFASLMLLVLSVVGASKSYAGDKLMSASFDSVR
                     VYYAMDKVTGAVASSVFNVTVITPKEVAYGKYDSFAYKGDTLRVISWSGSGSAPTLVL
                     TDFDTINNSNCPGIDTKIFRCAYMTFKITVASDDYGCPWIASFYSYTDLPGFGSYTAP
                     TVHNTICPTIPVASYDISWSENYVSHNKALRIQSTGSTVTTTLSTYLMEGGRLCDGSN
                     FSDNDGRGAYCRAVSELLTFTSYGCDKSTVTVTPTRHPVTDKVLHDIVVNVNTSSGQP
                     IDSTCRFQYVLNEL"
     gene            complement(6703..7254)
                     /gene="smrB"
                     /locus_tag="ACHY1N_004498"
     CDS             complement(6703..7254)
                     /gene="smrB"
                     /locus_tag="ACHY1N_004498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HFS4046682.1"
                     /translation="MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPV
                     KRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVEEWLPPELP"
     gene            7420..8352
                     /gene="prmB"
                     /locus_tag="ACHY1N_004499"
     CDS             7420..8352
                     /gene="prmB"
                     /locus_tag="ACHY1N_004499"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008276 - protein methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA];
                     GO_process: GO:0042273 - ribosomal large subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFS4046683.1"
                     /translation="MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGH
                     EFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPEAEVD
                     AVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKEQLIAAREHFAIYKD"
     gene            8387..9472
                     /gene="aroC"
                     /locus_tag="ACHY1N_004500"
     CDS             8387..9472
                     /gene="aroC"
                     /locus_tag="ACHY1N_004500"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFS4046684.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
                     GDIPLEIKDWSLVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGI
                     LGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRQRAQNADVKTDIPRW"
     gene            9476..10300
                     /gene="mepA"
                     /locus_tag="ACHY1N_004501"
     CDS             9476..10300
                     /gene="mepA"
                     /locus_tag="ACHY1N_004501"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HFS4046685.1"
                     /translation="MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGC
                     IVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVPTLWKPEI
                     FSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPPGDGCGAELQSWFAPPKPGTTKPEKKTPPPLPPSCQALLDEHVI"
     gene            10300..11109
                     /locus_tag="ACHY1N_004502"
     CDS             10300..11109
                     /locus_tag="ACHY1N_004502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFS4046686.1"
                     /translation="METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQ
                     YVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKLLYDSHGQEILHWLGMN"
     gene            11109..11657
                     /gene="epmC"
                     /locus_tag="ACHY1N_004503"
     CDS             11109..11657
                     /gene="epmC"
                     /locus_tag="ACHY1N_004503"
                     /EC_number="1.14.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
                     /protein_id="HFS4046687.1"
                     /translation="MNSTHHYEQLIEIFNSCFADEFNTRLIKGDDEPIYLPADAEVPY
                     NRIVFAHGFYASAIHEISHWCIAGKARRELVDFGYWYCPDGRDAQTQSQFEDVEVKPQ
                     ALDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLANGIPERPARFIKA
                     LQNYYHTPELTAEQFPWPEALN"
     gene            11691..11969
                     /locus_tag="ACHY1N_004504"
     CDS             11691..11969
                     /locus_tag="ACHY1N_004504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HFS4046688.1"
                     /translation="MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELES
                     GDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWENLFQQASQQ"
BASE COUNT         2980 a         2913 c         3124 g         2991 t
ORIGIN      
        1 gcggccccac accaaagaat acaattttct acgacctgtt ctttttggat cgcatgccgt
       61 attcaatggc tgggtataaa cattgggtat tgactgaatc aatgtattgt aatgtttata
      121 tttttaatta tttatagttt aaggacaaat aatgagtaag tttgttaaaa cagctattgc
      181 tgcggcaatg gtgatgggcg ttttcacctc tacggcaaca atcgctgcgg gtaacaacgg
      241 tactgcacgt ttttacggca ccattgaaga ctcagtgtgt tctatcgttc cggacgatca
      301 caaactggaa gttgatatgg gtgatatcgg tgccgaaaaa ctgaaaaata acggcaccac
      361 cacgccgaaa agtttccaga ttcgtctgca agattgcgta tttgatactc aggaaacaat
      421 gaccactacc tttactggta ccgtttcttc tgcaaatagc ggcaattatt acaccatttt
      481 caataccgat accggtgcgg catttaacaa tgttagcctg gcgatcggtg actctctggg
      541 tacctcttac aaaagcggca tgggtattga ccagaaaata gtgaaagaca cttctaccaa
      601 taaaggcaaa gcgaagcaga cactgaactt taaagcctgg ctggtcggcg cagctgatgc
      661 gccagatctg ggtaatttcg aagcaaatac caccttccag attacttacc tgtaaggcat
      721 acccccatag cgacactgct atgggggatt taaatggatt ttgaccgaac aagaataaaa
      781 acggatagaa acgtgtatgc ctgaccattc tctttttcga ttacggattc ttccgtggtg
      841 cattgcgctg gcaatgtcag ggagttatag cagtgtctgg gctgaagacg acattcagtt
      901 tgattcccgt tttctggaat taaaaggcga cacaaaaatt gatctgaagc gtttttccag
      961 ccagggatat gttgagcccg gaaaatacaa tttacaggtt caactaaata aacagccatt
     1021 ggcggaagag tacgatattt actggtatgc tggtgaagat gacgcgagca aaagctatgc
     1081 ttgtctgaca ccggaactgg tagcgcagtt tggtttaaaa gaagacgtgg cgaacaatct
     1141 gcaatggagc cacgatgcta aatgcctgaa atccggtcaa ctggaaggca tggaaattaa
     1201 ggctgattta agccagtccg cattagtcat ttcactgcca caggcttacc tcgaatatac
     1261 ttatcccgac tgggatccgc cttcacgttg ggatgacggc atctccggga tcgtcgcgga
     1321 ctacagcatc aacgcacaaa cccggcacga agaaaatggc ggtgatgata gtaacgagat
     1381 cagcggcaac gggacggtcg gggttaacct ggggccgtgg cgtatgcgtg ctgactggca
     1441 gactaactat caacatactc gcagtaatga tgacgatgaa ttcagcggcg atgaaactca
     1501 aaaaaaatgg gagtggagtc gctactatgc ttggcgggcg ttaccatcat taaaagccaa
     1561 actggcgctg ggcgaggatt acctcagatc cgatattttt gatggtttta actatgttgg
     1621 tggcagtgtc agtactgacg atcaaatgtt gcctcccaat ctgcgcggct acgcgccaga
     1681 catttccggc gtggcacaca ccacagcaaa agtgaccgtc agccagatgg ggcgtgtgat
     1741 ttacgaaacg caggttccgg ctggaccgtt tcgtattcag gatcttggtg attctgtctc
     1801 cggtacgttg catattcgca ttgaagaaca gaacggccag gtgcaggaat atgacatcag
     1861 caccgcctcg atgccatacc tcactcgccc aggtcaggtt cgctataaga tcatgatggg
     1921 ccgtccgcaa gagtggggac accatgtcga gggtgaattt ttttctggtg ctgaagcttc
     1981 ctgggggatc gctaacggct ggtcgttata tggcggcgca ctgggagatg aaaactatca
     2041 gtctgcggcg cttggcgtcg gtcgcgattt gtctacattc ggcgcggtcg cgtttgatgt
     2101 tactcactcg cacaccaaac tggataaaga caccgcttat ggcaaaggtt cgctggacgg
     2161 taactccttc cgtgtgagtt attccaaaga ctttgaccag ctcaacagcc gcgttacttt
     2221 tgctggatat cgcttctcgg aagagaactt tatgaccatg agcgagtatc tggatgccag
     2281 tgacagcgga atggtacgca cgggcaacga caaagagatg tacaccgcca cttataacca
     2341 gaacttccgc gatgcgggtg tttcggttta tctcaactat acccgccata cctactggga
     2401 tcgcgaggag cagacaaact acaacatcat gctctcgcac tatttcaata tgggcagtat
     2461 tcgtaatgtc agcatctcga tgactggcta ccgttacgag tatgacaacc aggccgacaa
     2521 aggcatgtac atttcgctca gtatgccgtg gggcgacaac agtaccgtta gctataacgg
     2581 taactatggc agtgggacgg acagcagtca ggtcggttat ttcagccgtg tcgatgacgc
     2641 gactcactat cagttgaacg tcggcaccag tgacaaacac accagcgttg acggctatta
     2701 cagccatgat ggttcgctgg cgcaggttga cctcagtgcg aactaccatg aagggcaata
     2761 cacctctgcg ggcttgtcgt tacagggcgg cgcaacgctt actgcccacg gtggcgcact
     2821 tcaccgtacc cagaatatgg gcgggacacg cttgttgatt gatgccgatg gcgttgccga
     2881 tgttccggta gaaggtaacg gtgctgctgt ttataccaat atgtttggta aagccgtcgt
     2941 ttctgacgtc aataactatt accgcaatca ggcgtatatc gacctcaaca aactgccgga
     3001 aaacgccgaa gcaacccagt cggtggtaca agccacgcta actgaagggg cgattggcta
     3061 ccgcaaattt gccgtcatca gtggtcaaaa agcgatggcg gtgctgcgtt tacaagacgg
     3121 cagccatcct ccgtttggcg cagaagtaaa aaatgataac gagcagacag tgggccttgt
     3181 cgatgatgac ggcaatgttt atctggctgg ggtgaaacct ggcgaacaca tgagtgtgtt
     3241 ctggagtggt gttgcgcatt gcgatatcaa cctgccggac ccgctgcctg ccgatctgtt
     3301 taacggcttg ttactgccat gccagcataa aggcaacgtc gcgccggttg ttcctgatga
     3361 cataaagcct gtcattcagg agcagacgca acaggtgaca cccaccaatc cccctgtttc
     3421 tgtttcagct aaccaataac gtgattaagg aatgatccat gtctgattta ctttgctctg
     3481 ccaaattggg tgctacgacg ctagcgttac tgcttagcgc tgccagtttg tctgcccagg
     3541 cttctgtaac gccagatcgt acccgtttga tatttaatga aagcgacaaa tcaatcagcg
     3601 tgacgttgcg caataacgat ccgaaactgc cttatctggc ccaaagctgg atcgaagatg
     3661 aaaagggtaa caagatcagt tcaccgttaa ctgttctgcc accggtgcaa cgcatcgatt
     3721 caatgatgaa cgggcaggta aaagtgcagg gaatgccgga tatcaacaaa ttgcctgccg
     3781 atcgtgaaag cctgttctac ttcaacgtgc gtgagatccc gccaaaatca aacaaagcca
     3841 acacgctgca aatagcacta caaacgcgta ttaagttgtt ctggcgaccg aaggcgctgg
     3901 agaacgtcag catgaaaaac ccctggcaat ataaggttac tttaacccgc aacggtcagg
     3961 aatttaccgt caataacccg acaccgtatt acgtcatttt cagtaatgcc agcacacaga
     4021 aaaatggcaa tccggcagcc ggtttctcgc caatagtgat gtcgccgaaa acctctgcac
     4081 cgctgaatgt gaagatgggt agcgtgccgg tactgaccta tgtcaacgac tatggcgctc
     4141 ggatgccgct ctttttcact tgcaacggta acagttgcca ggtcgatgaa gagcagagcc
     4201 gcaaaggctg aggccgggag agccagtatg aaaggatctt gttctgtctg ggcggtaact
     4261 gggttactga tatgttgtgt tggtagcggc tttgcagttg cagcgagtaa gtcagtaagt
     4321 atgaatttac gggtgcttgt cgatgcccct cctccttgta cggtaaatgg tgcggcagtt
     4381 gagtttggta atgtattcat taataagatc aatggggttg attataaacg tcccattgac
     4441 tactcgcttg tttgtaacaa tctggcaatg gatgacctgc gtctacagat gcaggcgaca
     4501 acggtcgtga ttaacggtga aacagttatc agcacgggga ttcctgggtt tggtattcgg
     4561 gttcagaaaa gtagtgatca cacaatactc gacttaacct ctggctcatg gttgccattt
     4621 aatttttcct cgggagttcc cgttctggaa gctgtgccgg tgaaacagag tggtacaacg
     4681 ttagcggcag ctgaatttaa cgccagtgcc acaattgtgg tggattacca atgaaacgga
     4741 tctcgcttat tttgctgtgg ggcttttgct cgatggcact ctcaaacgtc tcttttcacg
     4801 gttatttagt gcagccacct aactgcacga ttagcaacgc tcaaaccatt gaaataactt
     4861 ttcaggatgt gcttattgat gacattaatg gcagcaatta tgagcaaacc gtgccgtatt
     4921 ccattacctg cgatacggcg gttcgcgacc cattaatgga aatgaccttg agctggagtg
     4981 gcacaccaag cgattttgat aatgctgcag taagcagcaa tatcactggt ttaggcattc
     5041 agctcaaaca ggcagggcag agttttacga tcaatacgcc acttgtggtg aatgaaaccg
     5101 atttaccggt gttaacggct gtgccagtaa aaaagagtgg tgtcgttctg ccagaggcgg
     5161 actttgaggc ctgggccacg ttacaggtag attaccaatg aagaaaaagc gtacgttgtt
     5221 ttttattagt agcctgatgt tgctgggcag tggaaccaca atagcaggag ataatttgca
     5281 ctttaccggc aatttaatca gtaaatcgtg tacgccagtg attaatggta gccagttggc
     5341 agaagtacat tttcctgcca ttgccgccag cgatttaatg aaccttgggc agtcagagcg
     5401 agtgccattg gtgtttcaat tgaaagattg tcatagttct acattgttta atgtcaaagt
     5461 aacgttgaca ggaacagaag atagtgctct acccggcttt ctggcctttg actcctcgtc
     5521 atcagcatcc ggcgctggga ttggtattga aactgcggca ggcacatcgg tgccaatcaa
     5581 caatacaaca ggcgtcacgc tcccgctgaa tcagggaaat aacagcctaa attttaatac
     5641 ctggttacag gcaaagagcg ggcgagatgt aacgtccgga gactttagtg ccacagtgac
     5701 ggcaaccttt gagtatttct gaaatgaaaa aatggaccat aattttcgcg agcctaatgc
     5761 tgctcgttct gagtgttgtc ggcgcatcta agagttatgc tggagataaa cttatgagtg
     5821 cgagttttga cagtgtgaga gtttattatg ccatggacaa ggtaaccggt gctgtagcga
     5881 gcagtgtttt caatgttacg gtgataacgc caaaggaggt tgcatatggg aaatatgatt
     5941 cttttgcgta taaaggcgat acgttgcggg ttatttcctg gtctgggtcg ggttcagctc
     6001 caactttggt actgactgac tttgatacaa ttaataactc aaattgccct ggcatagata
     6061 cgaaaatttt tcgttgtgca tatatgacgt ttaaaattac cgttgcatct gatgattatg
     6121 gttgcccttg gatcgcatcc ttttattcct atacagattt acccggattt ggaagctata
     6181 cggcccctac agtgcataac acaatatgcc caacgatacc ggtcgcttca tacgatatct
     6241 cctggagtga aaattatgtc agccataata aggcgttacg aattcagtcc acggggtcaa
     6301 cagtgaccac cacgctttcg acctacttga tggaaggcgg cagactctgt gatggcagta
     6361 atttttctga taatgatggc agaggagcat actgccgcgc ggtatcagaa ttgttaacct
     6421 ttacctctta cggttgtgat aaatcaacgg taacggttac gccaactcgt catccggtaa
     6481 cggataaagt actacacgat attgtggtga atgtgaatac cagtagtggg caaccgattg
     6541 attcgacgtg tcgttttcag tatgtattga atgaactgta gttcgtagta ttgctctgat
     6601 gcgtcttatc aggcctacga agtgaattgc aatttattga attatcacat atttgtaggc
     6661 cggataaggc gtttacgctg ctccggcatt tgctgccagc attcagggca actccggcgg
     6721 caaccactct tccacttcaa tcaacaccaa caaagccgca tcaccgccgt actctttcgg
     6781 tgcctggtga aatgccatca catgcggatg ttgtgccagc cacagcggtg tttgttgctt
     6841 caaaatatgc ttcccgtgcc catgcatcac gcaggcacaa aacacatgtt cgcggcgaca
     6901 ggcggcaatc aacgcgccca gttcctgctt ggcctgcagc tgcgtcagac cgtgtaaatc
     6961 caaaaacaat tccggtgaat aatcgccgcg gcgcagtttc ttcgcctcaa aatggctgac
     7021 atccgggcga acatatttca ccggaccttc ggtatttaat aacggctgaa actcatcgga
     7081 gaaataatgg ctggcatcag cctgctcctg gatcaagcgt ttcaccggca cttcgctgat
     7141 ttttttacgc tgcggtcggt ggacaatcgt gtcctgctta atcttgcgag tccccgccat
     7201 caactggcga aacagagcct ggtcctcctc gctaagtgtt gttttctttt tcatttatct
     7261 gtctctattt ctaattttcc tacagtttac ccgactcgta gcacaatcga tcgttttaaa
     7321 cgtatttttc ctcactcacc gcgcgtgaat gctgatttat cgtcatcttc atggcaaact
     7381 agccgccgaa attattgcga tcatgccctg gaggaatacg tggataaaat tttcgttgat
     7441 gaagcagtaa atgagctgca aaccattcag gacatgttgc gctggtcggt aagccgcttc
     7501 agcgcggcaa atatctggta cggtcacggc accgataacc cgtgggatga agccgtacag
     7561 ctggtgttac catcgctcta cctgccgctg gatatcccgg aagatatgcg caccgcgcgt
     7621 ctgacctcca gcgaaaaaca ccgtattgtt gaacgcgtga tccgccgcgt caacgagcgc
     7681 attccggtgg cttacctgac caacaaagcc tggttctgcg gtcatgaatt ttacgtcgat
     7741 gaacgcgtgc tggtgccgcg ctcaccgatt ggtgaactga tcaacaataa atttgccgga
     7801 ctcatcagca agcaaccgca gcatatttta gatatgtgta ccggtagcgg ctgcatcgcc
     7861 attgcctgtg cttatgcctt cccggaagcg gaagtcgacg cggtagatat ctctcccgac
     7921 gcgctggcgg ttgccgaaca gaacatcgaa gaacacggtc tgatccacaa cgtcattccg
     7981 attcgttccg atctgttccg tgatttgccg aaagtgcaat acgatctgat tgtcactaac
     8041 ccgccgtatg tcgacgcgga agatatgtcc gacctgccaa acgaataccg tcacgagccg
     8101 gaactgggcc tggcatctgg caccgacggc ctgaaactga cgcgtcgcat tctcggtaac
     8161 gcggcagatt accttgcgga tgatggcgtg ttgatttgtg aagtgggcaa cagcatggta
     8221 catcttatgg aacaatatcc cgatgttccg ttcacctggc tggagtttga taacggcggc
     8281 gatggagtgt ttatgctcac caaagagcag cttattgccg cacgagaaca tttcgcgatt
     8341 tataaagatt aagtaaacac gcaaacacaa caataacgga gccgtgatgg ctggaaacac
     8401 aattggacaa ctctttcgcg taaccacctt cggcgaatcg cacgggctgg cgctcggctg
     8461 catcgtcgat ggtgttccgc caggcattcc gctgacggaa gcggacctgc aacatgacct
     8521 tgatcgtcgt cgccctggga catcgcgcta taccacccag cgccgcgagc cggatcaggt
     8581 caaaatactc tccggtgttt ttgaaggcgt tactactggc accagcattg gcttgttgat
     8641 cgaaaatacc gaccagcgtt ctcaggatta cagcgcaatt aaagacgtct tccgtccagg
     8701 ccatgctgat tacacctacg aacaaaaata cggtctgcgc gattatcgcg gcggtggacg
     8761 ttcttccgcc cgcgaaaccg ccatgcgcgt ggcggcaggg gcgattgcca aaaaatatct
     8821 cgccgagaaa tttggtattg aaatccgcgg ctgcctgacc cagatgggcg acattccgct
     8881 ggaaatcaaa gactggtcgc tggttgaaca aaatccgttc ttctgcccgg accccgacaa
     8941 aatcgacgcg ttagatgaac tgatgcgcgc gctgaaaaaa gagggcgact ccatcggcgc
     9001 gaaagtcacc gttgttgcca gtggtgtccc cgccggactt ggcgagccgg tctttgaccg
     9061 cctggatgcc gacatcgccc atgcgctgat gagcatcaac gcggtgaaag gcgtggaaat
     9121 tggcgacggt tttgacgtag tggcgctgcg cggcagccag aaccgcgacg aaatcaccaa
     9181 agacggtttc cagagcaacc atgcgggcgg cattctcggc ggtatcagca gcgggcagca
     9241 aatcattgcc catatggcgc tgaaaccgac ctccagcatt accgtgccgg ggcgcactat
     9301 taaccgcttt ggcgaagaag ttgagatgat caccaaaggc cgtcacgatc cctgtgtcgg
     9361 gatccgtgca gtgccgatcg cagaagcgat gctggcgatc gttttaatgg atcacctgtt
     9421 acggcagcgg gcgcaaaatg ccgatgtgaa gactgatatt ccacgctggt aaaaaatgaa
     9481 caaaaccgcg attgcgctgc tggctctgct tgccagtagc gctagcctgg cagcgacgcc
     9541 gtggcaaaaa ataacccaac ctgtgccggg tagcgcacaa tcgataggca gtttttctaa
     9601 tggctgtatt gtcggcgctg acacgttgcc gatacagtcc gaacattatc aggtcatgcg
     9661 taccgatcag cgtcgctatt tcggtcaccc ggatctggtg atgtttatcc agcgtctgag
     9721 tagccaggtg agcaatctgg gcatgggtac ggtgctgatt ggcgatatgg ggatgcccgc
     9781 tggtgggcgt ttcaacggcg gtcatgccag ccaccagacc ggactggatg tcgatatctt
     9841 tctgcaactg ccgaaaactc gctggacctc cgcgcagctc ttgcgcccgc aagcactgga
     9901 cttagtttcc cgcgacggta aacacgttgt tccgacgctg tggaagccag aaattttcag
     9961 cttgatcaaa ctcgccgccc aggacaaaga cgtcacacgc atttttgtta atccggcgat
    10021 taaacaacaa ctttgccttg atgcgggcac cgatcgcgac tggttgcgca aagtgcgacc
    10081 ctggttccag catcgcgcgc atatgcatgt acgattacgt tgtcctgccg atagtctgga
    10141 gtgtgaagat caacctttac cgccaccagg cgatggttgc ggggcagaac tgcaaagctg
    10201 gtttgcacct ccaaaaccgg gaacaacaaa gcctgagaag aagacaccgc ctccgttgcc
    10261 gccttcctgc caggcgctac tggatgagca cgtgatctaa tggaaacgtt taatagcctg
    10321 tttatggttt ccccgctgtt gctgggagtt ctcttttttg tcgccatgct ggcgggattt
    10381 atcgactcga ttgccggtgg cggtgggtta ctcaccattc cggcattgat ggcagcggga
    10441 atgtctcccg ctaacgcgtt ggcaaccaat aaactgcaag cctgcggcgg ctctatttcc
    10501 gccactatct actttattcg ccgcaaagtg gttagtttaa gcgatcagaa actcaatatt
    10561 gccatgacct ttgtcggctc aatgagcggc gcactgttgg tacagtacgt tcaggctgat
    10621 gtcttacggc agattttgcc cattctggtg atttgtatcg gcctctattt cttgctgatg
    10681 ccaaagctgg gtgaagaaga tcgccagcgc cggatgtacg gtttaccctt cgcgttaatt
    10741 gccggtggct gcgtcggttt ttatgacgga ttctttggcc cggctgccgg atcgttttac
    10801 gcgctggcct tcgttacgct gtgcggattc aacctcgcca aagccacggc tcacgccaaa
    10861 ttactcaacg caacgtcaaa cattggcggt ctgctgctgt ttattctcgg cggcaaagtg
    10921 atttgggcga cgggctttgt gatgctggtg gggcagttcc tcggcgcgcg catgggttca
    10981 cggctggtgt tgagcaaagg acaaaagctg atccgcccga tgattgttat cgtctcggcg
    11041 gtgatgagtg ccaaattact ttacgatagc cacggacagg agatcctcca ctggttgggg
    11101 atgaactaat gaacagtaca caccactatg agcagttgat tgaaattttt aatagctgct
    11161 ttgccgatga atttaatacc cgtctgatta aaggcgacga cgaaccgatc tatcttcctg
    11221 ctgatgcgga agtaccgtat aaccgaattg tctttgccca cggcttttat gccagcgcaa
    11281 ttcatgagat ttcgcactgg tgtattgccg gaaaagcgcg ccgtgagctg gttgatttcg
    11341 gctactggta ttgcccggat gggcgtgatg cccaaacgca aagccagttt gaagatgttg
    11401 aagtgaagcc gcaggcactc gactggttgt tctgtgtggc ggcgggatat ccgtttaacg
    11461 tcagttgcga caatctggaa ggcgacttcg aaccggatcg tgtggtgttt caacggcggg
    11521 tacatgcgca ggtgatggat tacctagcaa acggcattcc tgaacgcccg gcacgcttca
    11581 ttaaagcact acaaaattat tatcacacgc cggaacttac ggcggaacag ttcccgtggc
    11641 cggaagcgct caactaaagc cagcgccacg ttttacaatg aggaaagaag atgatcgcgg
    11701 agtttgaatc acgcattctg gcattaatcg acggtatggt tgaccatgcc agtgatgatg
    11761 agttgtttgc cagtgggtat ttgcgtggcc acctgacatt agccatcgca gaactggaaa
    11821 gtggtgatga ccactccgct caggcggtgc atacgaccgt tagccagagt ctggaaaaag
    11881 ccattggtgc cggtgaattg tcgccgcgtg accaggcgct ggtgaccgat atgtgggaaa
    11941 acctgtttca gcaggcgtca cagcagtaag ttgcggcgtc tggagcacca tgcctgatgc
    12001 gacgctta
//
LOCUS       DAZUDJ010000109        11886 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.110, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000109 DAZUDJ010000000
VERSION     DAZUDJ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11886
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.110"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..190
                     /locus_tag="ACHY1N_004505"
                     /pseudo
     CDS             1..190
                     /locus_tag="ACHY1N_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            713..1228
                     /gene="ehxC"
                     /locus_tag="ACHY1N_004506"
                     /gene_synonym="hlyC"
     CDS             713..1228
                     /gene="ehxC"
                     /locus_tag="ACHY1N_004506"
                     /gene_synonym="hlyC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterohemolysin-activating
                     lysine-acyltransferase EhxC"
                     /protein_id="HFS4046689.1"
                     /translation="MKSNAFDVMGKVAWLWACSPLHKKWPLSVFAINVIPAIQTNQFA
                     LLIKDELPVAFCSWASLDLECEVKYINDVTSLYAKDWMSGERKWFIDWIAPFGHNMEL
                     YKYMRKKYPYELFRAIRLDESSKTGKIAEFHGGGIDKKLASKIFRQYHHELMSEVKNR
                     QDFNFNIEKEN"
     gene            1230..4226
                     /gene="ehxA"
                     /locus_tag="ACHY1N_004507"
     CDS             1230..4226
                     /gene="ehxA"
                     /locus_tag="ACHY1N_004507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterohemolysin EhxA"
                     /protein_id="HFS4046690.1"
                     /translation="MTVNKIKNIFNNATLTTKSAFNTASSSVRSAGKKLILLIPDNYE
                     AQGVGINELVKAADELGIEIHRTERDDTAIANQFFGAAEKVVGLTERGVAIFAPQLDK
                     LLQKYQKVGSKIGRTAENVGNNLGKAGTVLSALQNFTGIALSGMALDELLRKQREGED
                     ISQNDIAKSSIELINQLVDTVSSINSTVDSFSEQLNQLGSFLSSKPRLSSVGGKLQNL
                     PDLGSLGDGLDVVSGILSAVSASFILGNSDAHTGTKAAAGIELTTQVLGNVGKAVSQY
                     ILAQRMAQGLSTTAASAGLITSAVMLAISPLSFLAAADKFERAKQLESYSERFKKLNY
                     EGDALLAAFHKETGAIDAALTTINTVLSSVSAGVSAASSASLIGAPISMLVSALTGTI
                     SGILEASKQAMFEHVAEKFAARINEWEKEHGKNYFENGYDARHAAFLEDSLSLLADFS
                     RQHAVERAVAITQQHWDEKIGELAGITRNADRSQSGKAYINYLENGGLLEAQPKEFTQ
                     QVFDPQKGTIDLSTGNVSSVLTFITPTFTPGEEVRERKQSGKYEYMTSLIVNGKDTWS
                     VKGIKNHKGVYDYSKLIQFVEKNNKHYQARMISELGDKDDVVYSGAGSSEVFAGEGHD
                     TVSYNKTDVGKLTIDATGASKPGEYIVSKNMYGDVKVLQEVVKEQEVSVGKRTEKIQY
                     RDFEFRTGGIPYDVIDNLHSVEELIGGKHDDEFKGGKFNDIFHGADGNDYIEGNYGND
                     RLYGDDGDDYISGGQGDDQLFGGSGNDKLSGGDGNNYLTGGSGNDELQAHGAYNILSG
                     GTGDDKLYGGGGIDLLDGGEGNDYLNGGFGNDIYVYRQNYGHHTIADEGGKGDRLHLS
                     DISFDDIAFKRVGNDLIMNKAINGVLSFNESNDVNGITFKNWFAKDASGADNHLVEVI
                     TDKDGREIKVDKIPHNNNERSGYIKASNIASEKNMVNITSVANDINKIISSVSGFDSG
                     DERLASLYNLSLHQNNTHSTTLTTTV"
     gene            4276..6396
                     /gene="ehxB"
                     /locus_tag="ACHY1N_004508"
                     /gene_synonym="hlyB"
     CDS             4276..6396
                     /gene="ehxB"
                     /locus_tag="ACHY1N_004508"
                     /gene_synonym="hlyB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterohemolysin T1SS ABC transporter
                     permease/ATPase EhxB"
                     /protein_id="HFS4046691.1"
                     /translation="MMSKCSSHNSLYALILLAQYHNITVNAETIRHQYNTHTQDFGVT
                     EWLLAAKSIGLKAKYVEKHFSRLSIISLPALIWRDDGKHYILSRVTKDSSRYLVYDPE
                     QHQSLTFSRDEFEKLYQGKVILVTSRATVVGELAKFDFSWFIPSVVKYRRILLEVLTV
                     SAFIQFLALITPLFFQVVMDKVLVHRGFSTLNIITIAFIIVILFEVILTGARTYIFSH
                     TTSRIDVELSAKLFRHLLALPVSYFENRRVGETVARVRELEQIRNFLTGQALTSVLDL
                     FFSVIFFCVMWYYSPQLTLVILLSLPCYVIWSLFISPLLRRRLDDKFLRNAENQAFLV
                     ETVTAINTIKSMAVSPQMIATWDKQLAGYVASSFRVNLVAMTGQQGIQLIQKSVMVIS
                     LWMGAHLVISGEISIGQLIAFNMLAGQVIAPVIRLAHLWQDFQQVGISVERLGDVLNT
                     PVEKKSGRNILPEIQGDIEFKNVRFRYSSDGNVILNNINLYISKGDVIGIVGRSGSGK
                     STLTKLLQRFYIPETGQILIDGHDLSLADPEWLRRQIGVVLQENILLNRSIIDNITLA
                     SPAVSMEQAIEAARLAGAHDFITELKEGYNTIVGEQGVGLSGGQRQRIAIARALVTNP
                     RILIFDEATSALDYESENIIMKNMSRICKNRTVIIIAHRLSTVKNANRIIVMDNGFIS
                     EDGTHKELISKKDSLYAYLYQLQA"
     gene            6400..7839
                     /gene="ehxD"
                     /locus_tag="ACHY1N_004509"
     CDS             6400..7839
                     /gene="ehxD"
                     /locus_tag="ACHY1N_004509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterohemolysin T1SS ABC transporter subunit
                     EhxD"
                     /protein_id="HFS4046692.1"
                     /translation="MRFYMKGLWDLVCRYKTVFSDVWKIRHTLDAPVREKDEYAFLPA
                     HLELIETPVSRRSHFVVWSILLFVIISLLLSVLGKVEVVSVANGKFTHSGRSKEIKPI
                     ENAIVEKIMVKDGSFVKKNDPLVELTVPGVESDILKSEASLLYEKTEQYRYAILSESI
                     QRNELPEIRITDFPGGEDNAGGEHFQRVSSLIKEQFMTWQNRKNQKQLTLNKKIVERD
                     AALARVSLYEHQVSQEGRKLNDFKYLLNKKAVSQHSVMEQENSYIQAKNEHAVWLAQV
                     SQLEKEIELVREELALETNIFRSEIIEKHRKSTDNIVLLEHELEKNRQRKASSFIKAP
                     VSGTVQELNIHTEGGVVTTAETLMIIVPDNDILEVTASVLNKDIGFIQPGQEVVIKVD
                     AYPYTRHGYLTGKVKNITADSVSVPDTGLVFNVIISVDRNDIQGERKKIPVTAGMTVM
                     AEIKTGVRSVISYLLSPLKETINESLRER"
     gene            7906..8049
                     /locus_tag="ACHY1N_004510"
                     /pseudo
     CDS             7906..8049
                     /locus_tag="ACHY1N_004510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            8053..8244
                     /locus_tag="ACHY1N_004511"
                     /pseudo
     CDS             8053..8244
                     /locus_tag="ACHY1N_004511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449473.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II-degrading bacteriocin"
     gene            complement(8252..8605)
                     /gene="cmi"
                     /locus_tag="ACHY1N_004512"
     CDS             complement(8252..8605)
                     /gene="cmi"
                     /locus_tag="ACHY1N_004512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_104216667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin M immunity protein"
                     /protein_id="HFS4046693.1"
                     /translation="MKVISMKFIFILTIIALAAVFFWSEDKGPACYQVSDEQARTFVK
                     NDYLQRMKRWDNDVQLLGTEIPKITWEKIERSLTDVEDEKTLLVPFKAEGPEGKRMYY
                     GIYHCEEGYVEYAND"
     gene            complement(8778..9560)
                     /locus_tag="ACHY1N_004513"
     CDS             complement(8778..9560)
                     /locus_tag="ACHY1N_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001164193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HFS4046694.1"
                     /translation="MQHLPAPIHHARDAAQLPVAIDYPAALALRQMSMVHDELPKYLL
                     APEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLTPPYPFVQLATLKQR
                     TEKAARTAGRTPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNKRTGRTEKARI
                     WEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMG
                     HKSISSTEVYTKVFALDVAARHRVQFSMPESDAVTMLKNKHA"
     gene            complement(9562..9975)
                     /locus_tag="ACHY1N_004514"
     CDS             complement(9562..9975)
                     /locus_tag="ACHY1N_004514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046695.1"
                     /translation="MFFIENEGQAVARTDYWQSVQAQAGYVYLSWNAGAARLLVPDAA
                     KHLLREMRGAEYVIISKGTLHGRDALELIFEDGSDAPFVIHMLSEQCDRLLPENNQGG
                     GFVVTVWTRGGNQLRYPGKYRVVENLPDVSPWSEH"
     gene            10535..10765
                     /gene="vapB"
                     /locus_tag="ACHY1N_004515"
     CDS             10535..10765
                     /gene="vapB"
                     /locus_tag="ACHY1N_004515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="HFS4046696.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVR
                     PTWGSFLEYEKADPDFMAEREDVVSDEGRFNL"
     gene            10762..11178
                     /locus_tag="ACHY1N_004516"
     CDS             10762..11178
                     /locus_tag="ACHY1N_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HFS4046697.1"
                     /translation="MNKTYMLDTCICSFIMREQPEAVLKRLEQAVLRGHRIVVSAITY
                     SEMRFGATGPKASPRHVQLVDEFCARLDAILPWDRAAVDATTKIKVALRLAGTPIGPN
                     DTAIAGHAIAAGAILVTNNTREFERVPDLVLEDWVK"
     gene            complement(11340..>11886)
                     /locus_tag="ACHY1N_004517"
     CDS             complement(11340..>11886)
                     /locus_tag="ACHY1N_004517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000350636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046698.1"
                     /translation="MQICKSITASADCEEIIKLIYLRRYFEIVDERGDAYQLLSNLFH
                     RRVAPLDYREPAAAGSGYPKMAPEKIQQALRDIREYVDSFDYPRLQALVSSPDEIKNL
                     YRRCRNGYEKLQVFRLLELDQDHPVIRKFVNETYHIENEFICQLDPSRFDLIPEYVIM
                     ECDKLIALPPAANQSSVARIA"
BASE COUNT         3542 a         2232 c         2748 g         3364 t
ORIGIN      
        1 cgatgactgg ctgaagagag agatacagcg cgtatacgat gaaaatcatc aggtatacgg
       61 tgtgcgtaaa gtctggcgcc agttgttacg cgaaggtatc agggtggcca gatgtacagt
      121 ggcgcgcctc atggcggtta tgggacttgc cggtgttctc cggggtaaaa aggtccgtac
      181 taccgtcagc cgatttacgg gccgtaagta acgaagttgg atgcaaatgt cagatcgtgt
      241 gcgcctgtta tggctcggct ggtaagagag ccttataggc gcatttgaaa aaactccagc
      301 tataccggaa gatatttatt attaacagga gaggtttgct tttctgtgta ggtttagatt
      361 ttgtgtttgc agggtaaaca aaactgatta actcgtcatt tcggtaactg aaatagtttg
      421 ctgtattctg tttacaatct ctttaataag gcatttgtca cgtggctatt catatgaaaa
      481 tcatacgtta tcttacaaat caatcatctg agtgttataa tataacttag ctgtgatatg
      541 tgtaagaatg tttaggcaat atattattat cgctaatgtt gttttggttg ggagagattc
      601 tccttgcggt agctttttgt ttttagatgc ttcttgctta aaaagatata atttctgttc
      661 ttttatatag gattctttac atttactgag ttttcttatt tatttaaaca ttatgaaatc
      721 taatgctttt gacgtcatgg ggaaggttgc atggctatgg gcctgttctc ctctgcataa
      781 aaaatggcca ttatctgttt ttgctattaa tgtcatacct gctattcaga caaatcaatt
      841 tgctctctta ataaaggatg agcttcctgt agctttttgt agctgggcca gtttagatct
      901 ggaatgtgag gtaaaatata taaatgatgt aacatctttg tatgcaaaag actggatgtc
      961 gggagaaaga aagtggttta ttgactggat agctccattt ggacacaaca tggagttata
     1021 taaatacatg aggaaaaagt atccttatga gttattcaga gcaataaggt tagatgagag
     1081 cagtaaaaca ggaaaaatag ctgaatttca tggagggggg atagataaaa aactggcatc
     1141 aaaaatattc aggcaatacc atcatgaact tatgtctgaa gtaaaaaaca gacaagattt
     1201 taattttaat attgagaaag aaaactaata tgacagtaaa taaaataaag aacattttca
     1261 ataatgcgac attgactaca aaatcagcat ttaatacagc atcatcaagc gtacgttccg
     1321 ctggcaaaaa actcatatta ttaatacctg ataattatga agctcagggc gtgggtatta
     1381 atgagttggt caaagctgct gatgagcttg gaatagaaat acaccgtact gaacgagatg
     1441 atacagcgat tgcaaaccag ttttttggtg cagcagaaaa agttgtagga ttaactgaac
     1501 gtggtgttgc aatattcgca ccacaacttg acaaacttct gcagaagtat cagaaagttg
     1561 ggagtaaaat aggaagaacc gctgaaaatg taggtaataa tctgggaaaa gccggaacag
     1621 ttctctcagc actacagaat tttacgggga ttgctttatc aggcatggct cttgatgaat
     1681 tgctgagaaa acaacgggaa ggagaggata taagtcagaa tgatattgcc aaaagtagta
     1741 ttgaacttat taatcagctt gtagatacag tatcaagtat aaacagtacc gttgattcat
     1801 tttctgagca gcttaaccag cttggctcat ttttatccag taaacctcgc ttaagttctg
     1861 ttggtgggaa attacaaaat ttaccagacc tgggctccct gggggatggg ctggatgttg
     1921 tctccggaat tctttctgct gtatcagcaa gctttattct gggaaacagt gacgcacata
     1981 caggaacaaa agctgcagcg ggtatcgaac tgacaactca ggttcttgga aatgttggta
     2041 aagctgtttc gcaatatatt ctggctcaga gaatggcaca ggggttatcg acaacagctg
     2101 caagtgcggg tctgatcaca tcggctgtta tgctggctat cagtcctctt tctttcctgg
     2161 ctgctgcaga taaatttgag cgagctaagc agcttgaatc atattctgaa cgatttaaaa
     2221 aattgaatta tgaaggggat gctttactcg cagcctttca taaagaaacc ggagctatag
     2281 atgcagccct gacaacaata aatactgtcc tgagttctgt atctgcggga gttagtgcag
     2341 cctccagtgc atccctcata ggggccccga taagcatgct ggtgagtgca ttaaccggta
     2401 cgatatctgg cattctggaa gcatcaaaac aggctatgtt tgagcacgtt gcagagaaat
     2461 tcgctgctcg gatcaatgaa tgggaaaagg agcatggcaa aaattatttt gagaatggct
     2521 atgacgcaag acatgctgcg tttttagaag actctctgtc tttgcttgct gatttttctc
     2581 gtcagcatgc agtagaaaga gcagtcgcaa taacccagca acattgggat gagaagatcg
     2641 gtgaacttgc aggcataacc cgtaatgctg atcgcagtca gagtggtaag gcatatatta
     2701 attatctgga aaatggaggg cttttagagg ctcaaccgaa agagtttaca caacaagtgt
     2761 ttgatcctca aaaagggacc atagaccttt caacaggtaa tgtatcaagt gttttgacat
     2821 ttataacacc aacatttacc ccaggagaag aagttagaga aagaaaacag agtggtaaat
     2881 atgaatatat gacatctctt attgtaaatg gtaaggatac atggtctgta aaaggcataa
     2941 aaaatcataa aggtgtatat gattattcaa aattgattca gtttgttgaa aagaataaca
     3001 aacactatca ggcgagaatg atttctgaac tcggagataa agacgatgtg gtttattctg
     3061 gagcaggctc atcagaagta tttgctggtg aaggtcatga taccgtatct tataataaga
     3121 cggatgttgg taaactaaca attgatgcaa caggagcatc aaaacctggt gagtatatag
     3181 tttcaaaaaa tatgtatggt gacgtgaagg tattgcagga agtcgttaag gaacaggagg
     3241 tgtcagtagg gaagcgaaca gagaaaatac aatatcgtga ttttgaattc agaaccggtg
     3301 gaattcctta tgatgtaata gataatcttc attctgttga agagctcatt ggcggaaaac
     3361 atgatgatga attcaaaggc ggtaagttta atgatatatt ccatggcgca gatgggaacg
     3421 attatatcga aggtaattat ggtaatgatc gactatacgg cgatgatggg gatgattata
     3481 tatccggagg acagggagac gaccagttat ttggtggtag tggaaacgat aaattgagtg
     3541 gaggggatgg taataattat ctgacaggag gaagcggtaa tgatgagctt caggcacacg
     3601 gagcttataa tattctgtca ggtggtactg gtgatgataa actttatggt ggtggtggta
     3661 ttgatcttct ggatggaggg gaaggtaatg actatctgaa tggtggtttt ggtaatgata
     3721 tttatgttta taggcaaaac tatggtcatc atacaattgc agatgaagga ggtaaaggag
     3781 atcgtttgca cttatctgat attagctttg atgatatcgc atttaagaga gttggaaatg
     3841 atcttatcat gaataaagcc attaatggtg tactttcatt taatgagtca aatgatgtca
     3901 atgggataac atttaaaaac tggtttgcga aagatgcctc aggagcagat aatcatcttg
     3961 ttgaggttat aacagataaa gatggtcgag agataaaagt tgataaaata cctcataata
     4021 ataatgaacg gtcaggttat ataaaagcca gtaatatagc atctgaaaaa aacatggtta
     4081 atatcaccag tgttgccaat gatattaata agattatttc ttcagtttca gggttcgatt
     4141 caggtgatga acgattagca tctttatata atttatcctt acatcaaaac aacacacact
     4201 caacaacttt aacgacaact gtctgagact aaaagaggag gtgatggcca ttccaggagg
     4261 aatggtcatc gttatatgat gagtaaatgt agttctcata atagtctgta tgcactgata
     4321 ttgcttgcac aatatcataa tataactgtc aatgctgaaa ctataaggca tcagtataat
     4381 acccacacac aagattttgg ggtgactgaa tggttactgg cagcgaaatc cattggctta
     4441 aaagcaaaat atgtagaaaa acatttttcc agattgtcaa taatttcttt acctgcgttg
     4501 atatggcggg atgacggtaa gcattatata ttgtctcgtg ttactaaaga ttcatcacgc
     4561 tatcttgttt atgatccaga acaacatcag tcactaactt ttagtcggga tgagtttgaa
     4621 aaactgtatc agggaaaagt cattctggtt acgtcaagag caacagtagt cggagagtta
     4681 gctaaatttg atttttcttg gtttatcccc tctgttgtga aatacaggag gattttactt
     4741 gaggtgttaa ctgtttctgc ttttattcag tttcttgcgt taataacacc tctttttttt
     4801 caggttgtaa tggataaggt tttagttcac cgggggtttt caacgttaaa tattatcaca
     4861 atagcattta ttatagtgat actttttgaa gtgatattaa ccggagccag aacttatatt
     4921 ttctctcata ctacaagtcg tattgacgtc gaactgagcg ctaagttatt cagacatttg
     4981 cttgcattgc ctgtttcata ttttgaaaat cgcagggtcg gagagaccgt tgccagagta
     5041 agggaactgg agcaaattcg taatttttta accggacaag cgttgacatc agttcttgat
     5101 ctattttttt ctgtaatatt tttttgtgtc atgtggtatt acagccctca attaacactg
     5161 gttatattat tgtcactacc ttgttatgtt atatggtcat tgtttatatc acccttatta
     5221 cgtcgacgtc ttgatgataa gtttctcagg aatgcagaaa atcaagcttt tcttgtcgaa
     5281 acggtaacag caataaatac aattaaatcc atggcagtat caccacagat gattgctaca
     5341 tgggataaac aactggccgg gtatgttgct tccagtttca gggtaaatct ggttgcaatg
     5401 acagggcagc aggggataca gctgatacag aaaagtgtaa tggtaattag tctatggatg
     5461 ggagcacatc ttgtcatatc gggagagata agtatcgggc agttaatcgc gtttaatatg
     5521 cttgcaggtc aggtcattgc tcctgttatc agactggctc atctttggca ggattttcag
     5581 caggttggta tttctgttga gcgccttggt gatgtattaa atacaccggt agagaaaaag
     5641 tcaggcagaa atatactgcc ggaaattcag ggggatatcg aatttaaaaa tgtcagattt
     5701 cggtattctt ctgacggtaa tgttattttg aataatatta atttatacat atcaaagggg
     5761 gatgttatcg gtatagttgg ccgttctggt tcaggaaaaa gtacattaac aaaactgctt
     5821 cagcgctttt atataccaga gaccggacag attttaattg atgggcatga tttatcactt
     5881 gcagatccag aatggttacg acgccagatt ggtgttgtat tgcaggaaaa tatactatta
     5941 aatcgtagta ttatcgataa tattacatta gcttctccgg ctgtatctat ggaacaggct
     6001 attgaggcag ccagacttgc aggtgcccat gattttatta cagaactaaa agaagggtac
     6061 aatactattg ttggagaaca gggcgttggt ctttcaggag ggcagcgcca acggatcgca
     6121 atagcccggg ctcttgttac aaatcctcga attcttattt ttgatgaagc aaccagtgct
     6181 cttgattatg agtcggaaaa tataataatg aaaaatatgt caagaatatg taagaacaga
     6241 accgtaatta ttattgcaca caggttgtca actgtaaaaa atgcaaacag aataattgtt
     6301 atggataatg gctttatttc tgaagatggc acacataaag agcttatctc caaaaaagac
     6361 agtttatatg catatttata tcagttgcag gcataacgta tgcgctttta catgaaaggt
     6421 ttatgggatt tggtttgccg ttataagacg gttttttctg atgtctggaa aattcgtcac
     6481 acacttgatg ctcctgtgag agaaaaagat gagtatgcat ttcttcctgc tcaccttgaa
     6541 ctcattgaaa caccagtatc cagacgttct cattttgttg tatggagtat tttattattt
     6601 gtaattatat ctcttctctt atctgttctt gggaaagttg aagtggtttc agtagcaaat
     6661 ggtaagttta ctcatagtgg aagaagcaaa gaaataaaac cgatagagaa tgcgattgta
     6721 gaaaaaataa tggtaaaaga tggctctttt gtaaaaaaaa atgatccatt agttgaattg
     6781 acggtgcctg gtgttgaatc tgatatttta aaatcagaag catctttgtt gtatgaaaaa
     6841 acagaacaat atcgctacgc aattctttct gaatcaatac aacggaatga gcttcctgaa
     6901 ataaggataa cagattttcc tggcggagaa gataacgcgg gaggtgaaca ttttcagagg
     6961 gttagctcat taataaaaga gcaattcatg acatggcaga acagaaaaaa tcaaaagcag
     7021 ctcacattaa ataaaaaaat agttgaacgg gatgcagcgc ttgctcgtgt tagcctgtat
     7081 gagcatcagg tatcacagga aggaagaaaa ctcaatgatt ttaagtattt gttgaataaa
     7141 aaagctgttt ctcaacattc agttatggag caggaaaata gctatattca ggcaaaaaat
     7201 gaacatgcag tctggcttgc acaggtttct caacttgaaa aagaaataga acttgtgcgg
     7261 gaagaactgg cactggagac gaatatcttc agaagtgaaa ttatcgagaa gcacagaaaa
     7321 tcaacagata acattgtgtt gctggagcat gagcttgaaa aaaacaggca gagaaaagca
     7381 tcatctttta ttaaagctcc tgtgagtggt actgttcagg agttaaatat acatacagaa
     7441 ggtggtgttg tcacaacagc agaaacgctg atgattattg tccctgataa tgatattctc
     7501 gaagtaacag catctgtact taacaaggat atcggtttta tacaacctgg acaggaggtc
     7561 gttattaaag tagatgcata tccatataca cgtcatggtt accttacagg gaaagtaaaa
     7621 aatataactg cagattctgt ttctgttccg gatacagggc ttgtatttaa cgtgattata
     7681 tctgttgatc ggaatgatat acagggagaa agaaaaaaaa tccctgttac agctggaatg
     7741 actgttatgg cagaaataaa aaccggggtg cgtagtgtta tcagctatct tcttagtcca
     7801 ttaaaggaaa ctattaatga aagtttacgt gaacgttagt atataaataa catattggct
     7861 ttttatatga tatagattta tgaaataatc tcgtaaagat tatctatgtt atttaaacaa
     7921 gctatgatac agtttttatc tttaaaaaga gttaatggaa tggatagtat taaattactt
     7981 gataaagtta ttatctatca acaacagaat gagcaattat atccagcaca ggaacatctt
     8041 cttttacaat gttcatatga tgataaatac gattttaacg ccagcactca ccgtggcatc
     8101 atcggagagt cgctcacaag gctcggggcg atgttttctg gtaaagagta ccagatactg
     8161 cttcctggtg aaattcacat taaagaaagt ggtaagcgag aatataaggg ccgggattcc
     8221 ggccttttta tgcagccttt ataacagtgt attagtcatt cgcatattca acatatccct
     8281 cctcacaatg gtatatgcca taatacattc tcttaccctc cgggccttca gctttaaatg
     8341 ggacaagaag tgttttttca tcttcaacat ctgttaaact tctctcaatc ttttcccatg
     8401 taattttcgg gatttctgta ccaagaagtt gaacatcgtt gtcccagcgt ttcattcttt
     8461 gcaggtaatc attttttaca aacgttctgg cctgttcatc gctgacctga tagcatgccg
     8521 gacctttatc ttcagaccag aaaaaaacag cagcaagagc aataatcgtt aaaataaaaa
     8581 taaatttcat gctaattact ttcataaaat ctccacaact tctgtcgttc attcgatata
     8641 aaaaaacatt acgaatatat ccgtacaatg tgagcatact gtgaagtggc tttaacaatt
     8701 atgaaataat acaagagatc acatattgca gtggtctctt ttttatagaa gaaatcacaa
     8761 ttcataattg tgacttatta tgcatgtttg tttttcagca ttgtgaccgc atcggactca
     8821 ggcatcgaaa actgcacccg gtgccgggca gcgacatcca gcgcaaacac cttcgtgtag
     8881 acctccgttg agctgatgga cttatgcccc atcagactct gcaggacctt cagcggtata
     8941 ccggcataca gcatatgcat cgcataggaa tggcggaacg tatgtggcgt gaccgggaca
     9001 gagaacgtca caccatcagc ggcagcggcg gcaaccgcct ccccaatcca ggtcctgacc
     9061 gttctgtccg tcacttccca gatccgcgct ttctctgtcc tgcctgttcg tttattacgc
     9121 cgttccatgg ggattttcaa tgtggccacc atcgtctgca gctggctgac gtaccaggag
     9181 tcggagagcg gaaccagccg gtgagtctgc tgcccggcgg gcgttcttcc tgccgtcctg
     9241 gcggcttttt cggtccgttg tttcagggtc gcaagctgca caaacggata cggaggcgtg
     9301 agcgaaaaat ccccccgcgt cagcgccagt gcttcattaa tgcgcgcacc ggtgttccac
     9361 agtgtggcca gcagcatctt gcggcgcaga tccgggacgt aatggagcag ggcgctcact
     9421 tcaggggcca gcaggtattt gggcagttca tcatgaacca tcgacatctg gcggagtgcc
     9481 agcgctgccg gataatcgat ggcaacagga agctgagcgg catcccgggc atggtggatc
     9541 ggtgccggca ggtgctgcat atcagtgttc actccacggg gaaacgtcgg gcaggttttc
     9601 cacaacccgg tactttcccg gataacggag ctggttaccg ccacgcgtcc agacggtgac
     9661 aacaaaaccc cctccctggt tgttttcggg gagcaggcga tcgcactgct cactcagcat
     9721 gtggatcacg aacggcgcat cgctgccgtc ttcaaatatc agttccagcg catcgcggcc
     9781 atgcagcgtt cccttactga tgatgacgta ctcagccccc cgcatctccc tgagtaaatg
     9841 ttttgccgca tccgggacaa gcagcctggc tgcgccggca ttccagctga ggtagacata
     9901 tccggcctgc gcctgtacag actgccagta atccgttctg gcgacagcct gaccttcatt
     9961 ctcaataaaa aacatgggtg actccttttt tcttttccgg gcagggacgg tcatgcgata
    10021 acgtcatcca tcatcactgc tcttaccgtc acgccatgtg ataacatcat gccgttatca
    10081 tcatcaccat gataacaagc atccatataa ccacgctttt aaattaccgg aggaccattt
    10141 ccgacagatc cgatttttct gttattgacg ggttttcgga agtgtatcac gctgaggaaa
    10201 taatcatatc gctgttttcc gcccctgcgc gacgcatcac aggtcaggga gatgacacaa
    10261 catatagtgt catcagcaga tgaatccggc accacatgtt gtgatgacgg gaggtggcgt
    10321 tgtgtggggg gagaggaaga tcctgaacaa ccttttttcg gatctccgat aaaaaagaaa
    10381 gaaatagaga tatgctaaac atatgcctgg catctacata tgctaccgct atacatatgc
    10441 cacacatctg cctatactaa acatatgcac acacccggtg ctttgaatat tccggatatg
    10501 tttcacatat ccatatgctc gggagagaaa gaacatgaga accgtatcga tatttaaaaa
    10561 tggcaacaac cgcgccatcc gtctgcctcg tgatctggat tttgaggggg tgagcgagct
    10621 cgagatcgtc cgggaagggg acagcatcat cctgcgcccc gtccggccaa cctggggatc
    10681 attcctagag tacgaaaaag ccgatccaga ttttatggcg gagcgcgagg atgttgtcag
    10741 cgacgaaggg cgatttaacc tgtgaacaag acttatatgc ttgatacctg tatctgctcg
    10801 ttcatcatgc gtgaacagcc agaagccgtc ctgaagcgtc tggagcaggc ggtgctacgc
    10861 ggccaccgca tagtggtctc ggccatcacc tactctgaaa tgcgcttcgg ggctaccggc
    10921 ccaaaggcct caccacgtca cgtccaactg gtcgatgaat tctgcgcccg cctcgatgcc
    10981 atcctgccct gggatcgcgc cgcagtagac gccaccacga agattaaagt ggcactgcgg
    11041 ctggccggga cgccgatcgg cccgaacgac acggcgattg ccgggcacgc catcgccgcc
    11101 ggggcgatac tggtaacgaa taatacaaga gaatttgagc gggtgcctga cctggtgctg
    11161 gaagactggg tgaagtaaga cactcttttc aaagtcagga gataagggca ccaagaaaca
    11221 gcccgtatac gggctgtttt aacagatatc tacagtaagc ggtcctaaac tgtagggtat
    11281 cttcgaagat cagactatca gggagctaaa gcctatcttc cggcggcaaa aacagtggct
    11341 caagcgatac gggcaaccga gctctggttt gctgccggtg gcagggcgat gagcttgtca
    11401 cattccataa tcacgtactc cgggatgaga tcgaatctgg acggatctag ttgacagatg
    11461 aactcatttt caatgtggta cgtttcgtta acgaattttc gtattaccgg atggtcctga
    11521 tccagttcca gtaaacggaa tacctgcagt ttttcatagc cgttacgaca gcgacggtac
    11581 aggtttttta tttcatctgg gctgctgacg agagcctgaa gtcgcgggta atcaaaactg
    11641 tccacatact cccggatatc ccgcaaggcc tgctgaattt tctcaggagc cattttgggg
    11701 tagcccgagc ccgcagcggc aggctcgcga taatccagcg gggcgacgcg tcgatggaat
    11761 agattggata gaagctgata agcatcacca cgttcgtcaa cgatttcaaa gtagcgacga
    11821 agatagatga gcttaatgat ctcctcacag tctgctgacg cagtgatgga tttgcagatc
    11881 tgcatg
//
LOCUS       DAZUDJ010000110        11869 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.111, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000110 DAZUDJ010000000
VERSION     DAZUDJ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11869
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.111"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..484
                     /locus_tag="ACHY1N_004518"
     CDS             <1..484
                     /locus_tag="ACHY1N_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFS4046699.1"
                     /translation="PDFNYIYQNYGDDFVTHTAKFSGETVERAIERAIVSKLNIVVEG
                     TFRNAATPLQTLKKLKDAGYQTEVMIKTTSAALSWESTNERYSKDKEAGNIARKVDKN
                     HHDIVTGLLAENARKVFASNLSDKFAVYSREKMIFSSQAATNDDIATLIQNEISGNTQ
                     "
     gene            complement(520..1311)
                     /locus_tag="ACHY1N_004519"
     CDS             complement(520..1311)
                     /locus_tag="ACHY1N_004519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFS4046700.1"
                     /translation="MPLNGVSAAMRERVSQQLREIERRYDVKVLYACESGSRGWGFAS
                     PDSDYDVRFLYVHPLEWYLRVEAPRDVIELPIDDELDVSGWEWRKALGLLKGANPTLI
                     EWLDSPVVYQQDEETITALKAMVPKWFSPLRARWHYYSMARKNFRGYLQGDEVRLKKY
                     FYVLRPLLAVRWVEAGKGVPPMRFAELLAGSELDAPLRAEIDELLERKQRAGEAEYGP
                     RRPLLHAFIRAEQARGEIPPLLPDSREGDVKELDSLMYQTVMRRA"
     gene            complement(1317..2444)
                     /locus_tag="ACHY1N_004520"
     CDS             complement(1317..2444)
                     /locus_tag="ACHY1N_004520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="slipin family protein"
                     /protein_id="HFS4046701.1"
                     /translation="MIKKISVRKDQLALLSRNGDYYKVLHAGEHILPWFTTPEVLLIT
                     LDGSEVPDVLADYLRRFQPDWVERYCVVADLSETEAGALYMDGILQEILPPSTRRLYW
                     RVEDDLTLVRMNTQQVQVQTEVMNAVLQPRRKGAVKGRDAILTVQVPAWHVGVLKIDG
                     ETQALLPPGLTAYWKINHLVDAEVVDTRLQVLEVSGQEILTKDKVNLRINLAANWRYS
                     DVLLAFSQLTKPIDHLYRELQFALREAVGTRTLDELLEDKQVIDDVVSEQVKSRMLPF
                     GMEIASLGVKDIVLPGDMKNILAQLVEAEKSAQANVIRRREETAATRSLLNTAKVMEN
                     NPVALRLKELETLERVAERIDNISVFGGLDQVLHGLVNIKG"
     gene            2973..3245
                     /locus_tag="ACHY1N_004521"
     CDS             2973..3245
                     /locus_tag="ACHY1N_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HFS4046702.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDHARIAHGRVLTNSETNSIKK
                     EYIDKLMVEREAAAKKARQLKKKQAYKPDTEASFNWSANTPTHGRR"
     gene            complement(3246..4118)
                     /gene="rluF"
                     /locus_tag="ACHY1N_004522"
     CDS             complement(3246..4118)
                     /gene="rluF"
                     /locus_tag="ACHY1N_004522"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HFS4046703.1"
                     /translation="MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGD
                     QVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIENSSSEAKPKVKAKPKTAGIKRPLVKMEKTSEKGGRPASN
                     GKRFTSPGRKKKGR"
     gene            4330..5019
                     /gene="pepE"
                     /locus_tag="ACHY1N_004523"
     CDS             4330..5019
                     /gene="pepE"
                     /locus_tag="ACHY1N_004523"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HFS4046704.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQ
                     TWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGL
                     LAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTN
                     ALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGE
                     EAVPLEAGHRF"
     gene            complement(5110..6741)
                     /locus_tag="ACHY1N_004524"
     CDS             complement(5110..6741)
                     /locus_tag="ACHY1N_004524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HFS4046705.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLSLPKAELVI
                     YFHVFYNLVRCLVMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALAN
                     AARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEE
                     LAEEESRRWAEIIEMSLNLEQASDIVERMGGEIADKSLAARRAFSLDGLKELDALYEQ
                     LLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY"
     gene            complement(6961..10644)
                     /gene="metH"
                     /locus_tag="ACHY1N_004525"
     CDS             complement(6961..10644)
                     /gene="metH"
                     /locus_tag="ACHY1N_004525"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008705 - methionine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFS4046706.1"
                     /translation="MSSKVEQLRAQLNQRILVLDGGMGTMIQSYRLNEADFRGERFAD
                     WPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAE
                     INFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAQAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLP
                     EIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     NGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQG
                     KGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKIL
                     TEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRR
                     DDGTERLLELAEKYRGSKTDDTANAQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEA
                     RQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDF
                     AFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLR
                     QQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMV
                     KALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHT
                     EKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYA
                     RRKGMSVTEVERWLAPNLGYDAD"
     gene            10844..11668
                     /gene="iclR"
                     /locus_tag="ACHY1N_004526"
     CDS             10844..11668
                     /gene="iclR"
                     /locus_tag="ACHY1N_004526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HFS4046707.1"
                     /translation="MVAPIPAKRGRKPAVATAPATGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAIGAHAFMVGSSFLQSRNLL
                     AIVHPILRNLMEESGETVNMAVLDQSDHEAIIIDQVQCTHLMRMSAPIGGKLPMHASG
                     AGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHAL
                     GLRCLAACIFDEHREPFAAISISGPISRITDDSVTEFGAMVIKAAKEVTLAYGGMR"
BASE COUNT         2851 a         3259 c         2913 g         2846 t
ORIGIN      
        1 ccctgatttt aattatatct accaaaatta tggggatgat tttgttaccc atacagcgaa
       61 attttccggc gaaacggtcg aacgtgcaat tgagagagcg atagtcagta aactcaacat
      121 tgttgtcgaa ggaacatttc gtaatgccgc gacgccgtta caaacattaa aaaaactcaa
      181 agatgcaggc taccaaacag aagtcatgat aaaaacaacc tcagcggcat taagctggga
      241 aagcaccaat gaacggtata gtaaggacaa agaggcggga aatattgccc gaaaagtgga
      301 taaaaaccac catgatatcg tcaccggttt gctggcagaa aatgcccgca aggtgtttgc
      361 ttcgaacctg tcagataagt ttgcggtgta ttcgcgtgag aagatgatat ttagttcaca
      421 agcggcaacg aatgacgata ttgcaacact tatacagaat gaaatcagcg ggaatacaca
      481 ataataataa gagctgatgg cgtgaaataa cgccgggctt tatgcccggc gcattaccgt
      541 ctggtacatt aagctatcca gttccttaac gtccccttct ctgctatccg gtaacagcgg
      601 tggaatttcc ccacgtgcct gttccgcacg aataaacgca tgtaacaatg gacggcgcgg
      661 accatattcc gcttctcctg cgcgctgttt acgttccagt aattcgtcta tttctgcacg
      721 taacggcgca tcaagttcgc ttcccgccag taactcagca aagcgcattg gcggtacgcc
      781 tttacccgct tcgacccagc gcacggccag cagcggacgc agcacgtaaa agtatttttt
      841 cagccgcact tcgtcgcctt gtaaataacc gcgaaagttt ttccgcgcca tcgaataata
      901 atgccaacgc gcacgcagcg gagaaaacca cttcggcacc attgccttaa gcgccgttat
      961 cgtttcttca tcttgttgat agaccacagg agaatccagc cattctatca gcgtcggatt
     1021 cgcacctttc aataatccca gcgccttgcg ccactcccag cctgaaacat ctaactcgtc
     1081 gtcaataggc aactcaataa catcgcgcgg cgcctctact cgcagatacc attccagcgg
     1141 gtgaacatac aaaaaccgta catcgtagtc gctgtcgggc gaggcaaatc cccagccgcg
     1201 gctccctgat tcacaggcgt acagtacttt cacatcatac cgccgttcaa tttctcttaa
     1261 ctgctgcgat accctttctc gcatcgcagc actgactcca tttaatggca tgttactcac
     1321 cctttgatat taaccaaccc atgcagaacc tgatccagac cgccaaatac agagatgtta
     1381 tcgatccgtt cagccactct ctccagcgtt tccagttctt ttaagcgtaa cgctaccggg
     1441 ttgttttcca tgactttagc ggtattgagt aacgaacgcg tcgctgccgt ttcttcacgt
     1501 cggcgaatca cattggcctg cgcggatttc tccgcctcaa ccagctgcgc aaggatattt
     1561 ttcatatcgc caggcaggac gatatctttc acccctaacg aggcaatctc cataccaaat
     1621 ggcaacatgc gcgatttcac ctgttcgctg acaacgtcat caatgacctg tttatcttcc
     1681 agcaattcat ccaacgtacg cgtacctacc gcttcacgca gggcaaattg taattcccga
     1741 tacaaatgat caatcggctt cgttaactgg ctaaatgcca ataacacgtc gctgtagcgc
     1801 cagttagcgg cgaggttaat ccgcagattg accttatctt tcgttaagat ttcttgcccg
     1861 ctgacttcca gtacctgcaa gcgggtgtca accacttcag cgtcaaccag atggttaatt
     1921 ttccagtatg cggtcagccc cggcggtaac agcgcctgcg tttcaccatc gattttcagc
     1981 acgcctacat gccaggccgg aacctgcacc gttagtattg catcgcggcc tttaactgcc
     2041 cctttgcgcc gtggttgcaa taccgcattc atcacctccg tttgtacctg gacttgctgc
     2101 gtattcatcc gcaccagtgt caaatcatcc tctacacgcc agtacaaacg gcgcgttgat
     2161 ggcggcagga tctcctgcaa aataccgtcc atatacaacg ccccggcttc agtctccgac
     2221 aagtcggcca ccacgcaata tctttccacc caatcaggct gaaagcggcg caaataatcc
     2281 gccagcacgt cgggcacttc gctaccatcc agcgtaatca gcaacacttc cggggtagta
     2341 aaccagggta aaatatgctc gcctgcatgt agcactttgt agtaatcgcc gtttctggag
     2401 agtaatgcca gctgatcttt tcttacgctt attttcttaa tcattatcta ttccttgctt
     2461 aacagccgtc gcggaagcgg acacgaagcg acaggggaat tcccttttgc ctgttacccg
     2521 gcgtctttat cggcgacgtt atcggggatc gctgactgcg caatccctca ttttttattt
     2581 aataagttac aaccagtatt catttcagga atgaatgtgg gaatcgaacc cataattggc
     2641 gtcaaaggct gacggaacac gcccggaaaa cagcctgacc gttcctggtg tgccgacggg
     2701 gtttaacccc ctttgaaatt cagtatcaac gcaaaagtgt tattgcgaga agcgtgccag
     2761 aattgagaaa aattcttaac caaatgaaaa ataaagagtt agtgaattac ttttgtttgt
     2821 agggggaaaa cttttcgcta aatgtgtatc tgtatttatc gtcaattatc aagaaagata
     2881 aatatttaag aagagaacaa aggaatatta tcagttctgc ttgcaaatga attcccgtac
     2941 actgaatcca tcggctaact gagggcaaca tcatggcact cccgcgtatt acccaaaaag
     3001 agatgacaga gcgcgagcaa cgcgagctaa aaacgctgct ggaccacgcg cggattgcgc
     3061 atggtcgcgt actgaccaac tccgaaacca acagcattaa aaaagagtac atcgataagc
     3121 tgatggttga gcgtgaagca gctgcaaaaa aagcccgcca gttgaagaaa aagcaggctt
     3181 ataaaccaga tactgaagca tcgtttaact ggtcggctaa tacaccaacg cacggcaggc
     3241 gctgattaac gccccttctt tttacgcccc ggcgatgtga aacgtttacc atttgacgcc
     3301 gggcggccac ctttttctga tgttttttcc atcttcacca acgggcgttt gatgcccgcc
     3361 gttttcggtt tggccttcac tttaggtttt gcctcggaag aggaattttc gatgagctta
     3421 aacaggtcga ttaactcatc gtcagttaaa tcgcgccact cacccagcgg aatgccgctt
     3481 aagctgacgt tcataatgcg cgtacgttcc agctttttca cttcatagcc gaaatgctcg
     3541 cacatgcgcc ggatctgacg gttcagcccc tgcaccaggg taatgcggaa gacaaacggc
     3601 gcttcttttt tgactttgca ctttttcgtc accgtcccga ggatcggcac ccccgccccc
     3661 ataccacgaa taaattcatc ggtaatcggt ttatcgaccg tcaccagata ctctttctca
     3721 tgatcgttac ccgcacggag gatcttattc accagatcgc cgtgattggt gaggaaaatc
     3781 agcccctggg agtctttatc caggcggcca atcgggaaca cgcgtttgct gtggttaacg
     3841 aaatcgacaa tgttatcgcg ctcgccatct tcggtggtgc tgacaatacc gacgggcttg
     3901 ttcagggcga taagtaccaa atcttcggct tcccgaggct caatcaactg accgtttact
     3961 ttcacaacgt cgccgggttt cacctgatcg ccaatggtgg ctcgcttgcc attaaggaac
     4021 acattgcctt gctcgatata gcgatccgct tcgcggcgtg agcaaattcc gctttcgctg
     4081 atgtatttat ttaaacggac tgatgagtcg ggcagcataa attctcctgt aaaaaacgga
     4141 atataccgta cctttgggtt gataaaaaat agtcatgagc gaactatttg ttatttccat
     4201 tggcttgaat tcgttacctg ctcaaatcac tttccagaag caatgtgcga catcgtgagc
     4261 catgtcagta agtggttaaa ttcgcagtgg tagcatgcct cccgtgattt cttactaacc
     4321 ggagaagtaa tggaactgct tttattgagt aactcgacgc tgccgggtaa agcctggctg
     4381 gaacatgcac tgccgctaat tgctgaacag ttgcagggtc gccgctcagc ggtgtttatc
     4441 cctttcgctg gcgtaacgca gacctgggat gattacacag cgaaaacggc tgcggttctc
     4501 gctccgctgg gtgtttctgt caccggtatt catagcgttg tcgatcccgt tgccgcgatt
     4561 gaaaatgctg agatcgtgat tgtcggcggc gggaatactt tccagttgct gaaacagtgc
     4621 cgcgagcgcg ggctgctggc accaattact gacgtggtta aacgtggcgc tctgtatatt
     4681 ggctggagcg caggcgctaa ccttgcttgc ccaaccattc gtaccaccaa cgatatgccg
     4741 attgtcgatc cgcaaggttt cgatgcgcta aatctgttcc cgttgcaaat caacccgcac
     4801 ttcaccaacg cgctgccgga aggccataaa ggtgaaaccc gtgagcagcg tattcgcgaa
     4861 ctgctggtcg tcgcgccaga actgacgatt attggtctac cggaaggtaa ctggatcaca
     4921 gtgagtaaag gtcacgctac gctgggtggc ccgaacacca cttatgtgtt taaggctggt
     4981 gaagaagcgg tgccgctaga agctggtcac cgtttttaag tgaattgccg gatgcatgat
     5041 ccggcatctt gttcatagtg cctgatgcga cgcttgacgc gtcttatcag gcctacagga
     5101 ttcacaatat taatactcgt cccgtccttc atcttcatcc ggctgttcca gcacactgta
     5161 agccaccgaa caaaacagcg agttcaggcg ctgcatatct cccagtaagc ctaaatgtag
     5221 cgaactggtt tcaatgctct gcacgttttg ctgatgcagg cgatcgacgt gggcgtggga
     5281 atagcggcga ttaagaatgc gaaagcgatg cttactacgg cgcaaacgac gagcgctggt
     5341 gacatcgcca gagaagaaca ccgacattgc cagttttaaa ttactgagca attgctcata
     5401 gagcgcatcc agttccttca agccatcaag cgaaaatgcc cgccgtgctg ccagcgattt
     5461 atcggcaatt tcgccgccca tgcgctcgac gatatcggag gcctgttcaa ggttgagcga
     5521 catttcgatg atctccgccc agcggcgcga ctcttcctcc gccaactctt cttttggcat
     5581 ccgcgccaga tacagcttaa tggcggtgta gagaacgttg atatcatctg ccagcttacg
     5641 cagctctttc tcctgccgtg gctcgccgtg catcacttta tttagccctt ccatcatctg
     5701 ttccatggcg tcgccaatgc gcagggtttc gcgcgcggcg ttcgccagag caagcgtggg
     5761 cgtatccagc gcgctgacat ccagatgttt gggccgtagc tgggtatcca gttccggttc
     5821 atcgcgaata atcgttttgc aaaaccgtgc catcgggtca acaaatggca gcatgaccag
     5881 gcaacgtaca aggttgtaga agacgtggaa atagatcacc agttccgctt ttggcaatga
     5941 caacttcccc attgtctctg ccagcaaatg gacaaacggc aggataatca ggctacccac
     6001 cagcttaaac agcagactac ccagcgcgac acggcgggct gcggcattgg cggcactgtt
     6061 gttgagcatc gccagcagac cggaaccgag gttagcacca atcaccagac agagcgccac
     6121 ggggaaggag ataatgcctg cggcggtcag agtcgcggtc agcagtacag cagcaaggct
     6181 ggagtagctg ataatggcga acatcgcgcc aatcagcgca tccagcagaa tatcgccggt
     6241 cagcgaggca aagatcacct gaacgccgtt tgcctgggtg atcggcgtta cggcctgcac
     6301 aatcaactcc agcgccagca aaatcagccc aagaccaata ccgacgcggc ccagttgccc
     6361 ggcgcgtgac tgtttgcgtc cgaggaaaaa aatcacgccg ataaaaataa gtaacggtga
     6421 cagccaggat aagtcgaagg tgagaatacg cgccattagc gccgtcccga catctgcacc
     6481 cagcacaatg accagagccg gtgcgagggc taccagatcc tgagcgacaa acgaggtcac
     6541 cagcatggtg gtggcattac tgctctgtac cagtgcggta acgccgatcc ccgcgcaaaa
     6601 ggcgagcggc tttttttcga cgctccggct aaggacagta cgcaaacgcg cgccgaagac
     6661 gcgcattacg ccggttcgaa caatatgagt cccccagacc agcagggcga cggcagaaag
     6721 caggtgaagc agcgttaaca cgagttcagg ttctccttat cgttatatgt tcctgaagca
     6781 attgaatgac caaaggaccg gaaacacgct gactggcatc tttactgtgc cttttgacct
     6841 tcgtttttcc ggctaagatt attccagcct gattccagta taagtgtttc atattaataa
     6901 agagacaggg cactcattga gcgccctgtt tgttgtaagg aaaagtgaca gatttgtgaa
     6961 tcagtccgcg tcatacccca gattcggtgc cagccagcgc tcaacttcgg taacgctcat
     7021 acctttacgg cgggcataat cttcaacctg atcgcgctga atttgtgcta cagcgtagta
     7081 cttgctgtcc gggtggctga agtaccaacc cgaaaccgat gcaccgggcc acatggcgaa
     7141 agattctgtg agtttcatgc cagtgtgttt ttccacttcc agcagctccc agatggtggc
     7201 tttttccgta tgttccgggc aggccggata gcccggtgcc ggacggatgc cctggtagtt
     7261 ttcgcggatc agttcttcgt tgctgaggtt ctcgttcggc gcatagcccc agtagacttt
     7321 acgcacacgc tcatggagat actccgcaaa ggcttcggct aaacggtcgg caagcgcttt
     7381 caccatgatt ttgttgtaat catcgtgctg cgcttcaaag gcatcagcca gtgcgtcctc
     7441 ttccagcccg ccagtcacgg caaatgcgcc gatgtaatct gctttaccag aaagcttcgg
     7501 cgcaacgaag tcagcgagac agtagttagc gaatcccgtt ttttcggtct gttgacgcag
     7561 atggtggctg acgttgatca catgggtgcg cgtttcgtca cggtagattt caatgtcatc
     7621 gcccacacgg tttgccggga acaggcccac cacgccacgc ggattcagcg ttttctcggc
     7681 gcttaattta tccagcatgt cgttggcgtc tttaaacagc cgctgcgcct caacgcccac
     7741 cacttcatct tccagaatgc gcggatactt cccggccagc gaccaggtca taaagaacgg
     7801 tgtccagtcg atgtaattac gcagagtttc gatgctggct tcaacttcct gcacgccgag
     7861 acggtgcgcc accggcggcg tgtaagcctg ccagtcaaaa gcgaaatcgt tatcgcgcgc
     7921 cgcttccagc gtgaccggtg gtgtgcgcgg tttcttacgc ccgtgctgaa tacgtacggt
     7981 ttcgtactcc ttgcgggtac gagcgacaaa atcatcacgc tgagtatcgg aaagcagcgc
     8041 cgccaccaca ccaacggtgc gcgatgcgtt ctgtacatac accgtcgggc cgctgtagtt
     8101 ctgctcaatt ttcaccgccg tgtgcgcttt tgaggtcgtc gcgccgccaa tcaatagcgg
     8161 gatggtgaag ccctgacgct ccatctcttt cgccacgtta accatctcgt ccagcgacgg
     8221 cgtgataagc cccgaaagtc caatcagatc agcattcact tctttagcgg tacggagaat
     8281 tttttccgca ggcaccataa cgccgagatc gacaatttcg tagttgttac attgcagcac
     8341 cacgccaacg atatttttac cgatgtcgtg gacatcgcct ttcacggtgg cgatcaccat
     8401 cttgccgttg gttttaccct gctctttgct ggcttcaata aacggttcga gatacgccac
     8461 tgcctgtttc atgacgcgcg ccgatttgac cacctgtggc aggaacattt tcccttcgcc
     8521 aaacagatcg ccgaccacgt tcataccgtc catcagcggg ccttcaatca cttcaatcgg
     8581 gcgcgtagcc tgctggcggg cttcttcggt atcctgctcg ataaactcgg taatgccttt
     8641 aaccagcgag tattccagac gtttattcac ttcccacgag cgccactccg cctgctgggc
     8701 gttagcggtg tcgtcggttt tgctgccgcg atatttctcg gcaagctcca gtaaacgctc
     8761 agtgccatcg tcgcgacggt taagaatcac atcttccacc gcgtcgcgca gttcagcggg
     8821 taggtcgtcg taaatcgcca gttgcccggc gttgacgatc cccatatcca tgccattgcg
     8881 aatagcgtag tagaggaaca ccgcgtgaat ggcttcgcgc accggatcgt tgccacggaa
     8941 tgagaaagaa acgttagata caccgccgga aatcagcgcg tgcggcagtt cgcgtttgat
     9001 atcttcacac gcgccgataa agtcctgcgc gtagttgttg tgctcttcaa tgccggttgc
     9061 gaccgcgaag atgttcgggt cgaagatgat atcttctggc gggaagccaa cctcttcggt
     9121 gaggattttg tacgcccgac ggcaaatctc gattttccgt gcgcgggtat cggcctgtcc
     9181 ctgttcgtca aaggccatta ccaccactgc cgcaccgtaa cgacgcaaga gcttcgcgtg
     9241 atggataaag gcgtcgacgc cctctttcat cgagatagag ttaacaatgc ctttgccctg
     9301 gatacacttc agaccttttt caatgacatc ccattttgag gagtcgatca taatcggcac
     9361 gcgagcgata tccggttcac cggcaatcag attgagaaaa cgcaccatcg ccgcttcggc
     9421 gtcgagcatc ccttcatcca tgttgatatc gataatctgc gcaccgtttt ccacctgctg
     9481 gcgggccaca tccagtgcct cgctgtattt ctcttctttg atcaggcgct tgaacttagc
     9541 ggaaccggtg acgttggtgc gttcacccac gttcacaaac aggctatctt cgccaatgtt
     9601 cagcggctcc aggccggaca aacggcaggc tacggggatt tccggcagtt tgcgcggcgc
     9661 taatccttct actgcacgac tcatcgctgc aatatgttgt ggcgtggtgc cacagcagcc
     9721 gccgacgata ttgagaaaac ccgcttgcgc ccattcacgt atctgttttg ccatcgtgtc
     9781 ggcgtcgaga tcgtactcac caaaggcgtt gggtagcccg gcgttcgggt gcgcggtgac
     9841 gtagcattcc gcaatccgtg acagctcctg cacgtactgg cgcagttcat cgggccccag
     9901 cgcacagttc aggccaaagg tcagagcttc ggcgtggcgc aatgagttgt aaaatgcttc
     9961 ggtggtctgc ccggagagcg tgcgcccgga ggcgtcggtg atggtgccgg agatcataat
    10021 cggcagctca acgcccagcg cttcaaactc cgttttcacc gcaaaaaccg ccgctttggc
    10081 gttaagggtg tcgaaaacgg tttcaatcag gatcagatcc gcgccacctt ccaccagcgc
    10141 tttggtggac tctcgataag ccgccaccag cccgtcaaaa gtgatattac gaaatgccgg
    10201 atcatttacg tccggagaaa tagacgccgt gcggttggtc gggccgagaa caccggcaac
    10261 gtagcgcggt ttctccggcg tgcgcgcggt ccactcatca gcacaagctc gcgccagttt
    10321 cgccgccgca aagttgattt ccgccgacag ggattccatc tggtaatccg ccatcgcaat
    10381 ggtcgtggag ttgaaggtgt tggtttcgat gatatccgcg cccgcttcaa agtaggcgtt
    10441 gtggatagcg gcgatcactt ccggtttgct gagcaccagc aggtcgttgt tgcctttgag
    10501 atcgcatggc cagtcggcaa agcgttcacc acgaaaatcg gcttcgttca gtcgatagct
    10561 ctggatcatg gtgcccatac cgccgtccag caccagaata cgttgattta actgcgcacg
    10621 cagttgttcc actttgctgc tcacacttgc tcccgacacg ctcaacccag atttaataaa
    10681 aattcaacaa accatactgg cataaacgca tctgtggtaa aagcgaccac cacgcaacat
    10741 gagatttgtt caacattaac tcatcggatc agttcagcaa ctattgcatt agctaacaat
    10801 aaaaatgaaa atgatttcca cgatacagaa aaaggaggct gtcatggtcg cacccattcc
    10861 cgcgaaacgc ggcagaaaac ccgccgttgc caccgcacca gcgactggac aggttcagtc
    10921 tttaacgcgt ggcctgaaat tactggagtg gattgccgaa tccaatggca gtgtggcact
    10981 cacagagctg gcgcaacaag ccgggttacc caattccacg acccaccgcc tgctaaccac
    11041 gatgcaacag cagggtttcg tgcgtcaggt cggcgaactg ggacattggg caatcggcgc
    11101 acatgccttt atggtcggca gcagctttct ccagagccgt aatttgttag cgattgttca
    11161 ccctatcctg cgcaatttaa tggaagagtc tggcgaaacg gtcaatatgg cggtgcttga
    11221 tcaaagcgat cacgaagcga ttattatcga ccaggtacag tgtacgcatc tgatgcgaat
    11281 gtccgcgcct atcggcggta aattgccgat gcacgcttcc ggtgcgggta aagccttttt
    11341 agcccaactg agcgaagaac aggtgacgaa gctgctgcac cgcaaagggt tacatgccta
    11401 tacccacgca acgctggtgt ctcctgtaca tttaaaagaa gatctcgccc aaacgcgcaa
    11461 acggggttat tcatttgacg atgaggaaca tgcactgggg ctacgttgcc ttgcagcgtg
    11521 tattttcgat gagcaccgcg aaccgtttgc cgcaatttca atttccggac cgatttcacg
    11581 cattaccgat gacagcgtga ccgagtttgg cgcgatggtg attaaagcgg cgaaggaagt
    11641 gacgctggcg tacggtggaa tgcgctgact ttttctggcg ggcagaggca atattctgcc
    11701 catcatacct gagtggcaat agaataaggg tgtctgttaa tcgcattgac gccaaaataa
    11761 cttaatgtca tacacttcac acacttttat taactcagca ttatttttaa acatcaaacc
    11821 acttaatcat taacaaaatc gcaagatctc attccaccga aacttttac
//
LOCUS       DAZUDJ010000111        11815 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.112, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000111 DAZUDJ010000000
VERSION     DAZUDJ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11815
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.112"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(50..346)
                     /gene="yaaX"
                     /locus_tag="ACHY1N_004527"
     CDS             complement(50..346)
                     /gene="yaaX"
                     /locus_tag="ACHY1N_004527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HFS4046708.1"
                     /translation="MKKMQSIVLALSLVLVAPMAAQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHPHGPPPPPRHHKKAHHDHHGGHGPGKHHR"
     gene            complement(560..1846)
                     /gene="thrC"
                     /locus_tag="ACHY1N_004528"
     CDS             complement(560..1846)
                     /gene="thrC"
                     /locus_tag="ACHY1N_004528"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HFS4046709.1"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVESILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     gene            complement(1847..2779)
                     /gene="thrB"
                     /locus_tag="ACHY1N_004529"
     CDS             complement(1847..2779)
                     /gene="thrB"
                     /locus_tag="ACHY1N_004529"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HFS4046710.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
     gene            complement(2781..5243)
                     /gene="thrA"
                     /locus_tag="ACHY1N_004530"
     CDS             complement(2781..5243)
                     /gene="thrA"
                     /locus_tag="ACHY1N_004530"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009067 - aspartate family amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HFS4046711.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPESINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHLLRHAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGACRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     misc_feature    complement(5269..5388)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00506"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Thr leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00506"
     gene            complement(5324..5389)
                     /gene="thrL"
                     /locus_tag="ACHY1N_004531"
     CDS             complement(5324..5389)
                     /gene="thrL"
                     /locus_tag="ACHY1N_004531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HFS4046712.1"
                     /translation="MKRISTTITTTITITTGNGAG"
     gene            complement(5603..6289)
                     /gene="yjtD"
                     /locus_tag="ACHY1N_004532"
     CDS             complement(5603..6289)
                     /gene="yjtD"
                     /locus_tag="ACHY1N_004532"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HFS4046713.1"
                     /translation="MRITIILVAPARAENIGAAARAMKTMGFSELRIVDSQAHLEPAT
                     RWVAHGSGDIIDNIKVFPTLVESLHDVDFTVATTARSRAKYHYYATPVELVPLLEEKS
                     SWMSHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCYQLATLIQ
                     QPAKSDTTADQHQLQALRERVMALLTTLAVADDIKLVDWLQQRLGLLEQRDTAMLHRL
                     LHDIEKNITK"
     gene            complement(6689..6829)
                     /gene="yjjY"
                     /locus_tag="ACHY1N_004533"
     CDS             complement(6689..6829)
                     /gene="yjjY"
                     /locus_tag="ACHY1N_004533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YjjY"
                     /protein_id="HFS4046714.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTAVILTILT
                     AT"
     gene            6925..7641
                     /gene="arcA"
                     /locus_tag="ACHY1N_004534"
     CDS             6925..7641
                     /gene="arcA"
                     /locus_tag="ACHY1N_004534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003621071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HFS4046715.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLED"
     gene            complement(7701..9053)
                     /gene="creD"
                     /locus_tag="ACHY1N_004535"
     CDS             complement(7701..9053)
                     /gene="creD"
                     /locus_tag="ACHY1N_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HFS4046716.1"
                     /translation="MLKSPLFWKMTTLFGAVLLLLIPIMLIRQVIVERADYRSDVEDA
                     IRQSTSGPQKLVGPLIAIPVTELYTVQEEDKTVERKRSFIHFWLPESLMVDGNQNVEE
                     RKIGIYTGQVWHSDLTLKADFDVSRLSELNAPNIILGKPFIVISVGDARGIGVVKAPE
                     VNGTALTIEPGTGLEQGGQGVHIPLPEGDWRKQNLKLNMALNLSGTGDLSVVPAGRNS
                     EMTLTSNWPHPSFLGDFLPAKREVSESGFQAQWQSSWFANNLGERFASGNDTGWENFP
                     AFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHIGFTVAWIIASLIGALMNGIYLQAVLKGWRNSMLFTLALLLLDGVM
                     WGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKASKEVTMDDQLRIWK
                     "
     gene            complement(9111..10535)
                     /gene="creC"
                     /locus_tag="ACHY1N_004536"
     CDS             complement(9111..10535)
                     /gene="creC"
                     /locus_tag="ACHY1N_004536"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HFS4046717.1"
                     /translation="MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLID
                     TATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFRANIGGINKVRNEYHVYMTDSQG
                     KVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRL
                     IGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYAD
                     SVTDNKPVPLPDLGSSELRKLAQALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRG
                     AAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENRQEVVLTAVDVAALF
                     RRVSEARTVQLAEKNITLHVTPTEVNVAAEPALLDQALGNLLDNAIDFTPESGRITLS
                     AEVDQEHVTLKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFN
                     GEVTLRNVQEGGVLASLRLHRHFT"
     gene            complement(10535..11224)
                     /gene="creB"
                     /locus_tag="ACHY1N_004537"
     CDS             complement(10535..11224)
                     /gene="creB"
                     /locus_tag="ACHY1N_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HFS4046718.1"
                     /translation="MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKAR
                     QQVPDVMILDVGLPDISGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYV
                     AKPFSPREVCARVRTLLRRVKKFSSPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEF
                     LLLKTLLKSPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRGL"
     gene            complement(11237..11710)
                     /gene="creA"
                     /locus_tag="ACHY1N_004538"
     CDS             complement(11237..11710)
                     /gene="creA"
                     /locus_tag="ACHY1N_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HFS4046719.1"
                     /translation="MKYKHLILSLSLIMLGPLAHAEEIGSVDTVFKMIGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDRIKNGKAQGE
                     VVFKKRTSLVFKSLQVVRFYDAKRNALAYLAYSDKVVEGSPKNAISAVPVMPWRQ"
BASE COUNT         2937 a         3228 c         2808 g         2842 t
ORIGIN      
        1 agcgtcgcat caggcgctga atgccggatt gttacccggc atttgtcatt tagcggtgat
       61 gtttgcctgg accatgaccg ccgtgatgat catgatgagc tttcttatgg tggcgcggcg
      121 gtggcggcgg tccgtgtggg tgccagcgat tgcctcgcca ttcataatgt tgtttccacc
      181 agccgtggtc gcgccagtga ccgccatccc agtaataacc gcgattatca cgatcgccta
      241 tctgtaattt tactgacggg actaacgtaa tttccgcagc ctgcgctgcc atgggagcga
      301 ccagaaccag ggaaagtgcg agtacgatag attgcatctt tttcacaggt tactcctttt
      361 atcattgccc gttatgggtc gatatccgga gattacgcga tgagaacggc ggttgttatt
      421 ctccgcaatc ctaatctcta agttaccgca tttattgaga atttctcctt tttccctgtc
      481 gtttttctcc ataatttctt cataaaaaag ccgggctgca taaaagcaaa cccggcctga
      541 ttgagataat gaatagattt tactgatgat tcatcatcaa tttacgcaac gcagcaaaat
      601 cggcgggcag attatgtgaa agcaagggta aatcagcacg ttctgccagc tcttttggca
      661 gatccaacgt ttcaccgaga atcgattcca cgctctcttt aaatttcgcc ggatgcgcgg
      721 tgccgaggaa caagccatat tcgcctggat tcaactggtc acgcagcgca cgatacgcta
      781 cggcagcgtg cggctccgag gtgtagccca gttcttttaa ctcacgcatt gtctgttgcg
      841 tggtttcatc atccacggct gcataaccca gctctttcag ttgccagatt ttgcggcgga
      901 acaactcttc cacacgcggc cagttgttcg gctgactcac gtccatcgcg ttggataacg
      961 tcgcctgagt cgctttgggt gaccactgac cgtcgtgcag gaaacgtggc acggtatcgt
     1021 tcacgttggt cgcagcaata aaacgtttca ccggcagacc gagtgacttc gccagcagac
     1081 ccgccgtcaa atcgccgaag tttccgcttg gcaccgagac aaccagctgg ttgcgcgctt
     1141 cctgtggcag ctgcgcaaca gcttcaaagt agtagcaaat ctgcgccagc aaacggctga
     1201 tgttaatcga gttagctgag tttaacccca gcgccacttt cagttcttca tcatcaaacg
     1261 cctgcttcac cagcgcctga caggcatcga aatcgccgtc gatggcaaca gtttcgatat
     1321 tgccgcccaa cgtacagaac agtttttctt gcagtggact gattttgcct cgtggataga
     1381 ggataaccac tttcacattc ggtaaaccgt agaaagcatg agccactgcc gctccggtat
     1441 caccggaggt cgcggtcaga atggtcactg gcttatcgcc cgcaatatgg gtcagcattt
     1501 gtgccataaa gcgaccgccg aaatctttaa atgccagcgt tggcccgtgg aacaattcca
     1561 gacaaccgac atcgctttca acattggcga ccggagccgg gaaggcaaac gccgcgcgca
     1621 cgcgctcttc caggatttcc tgcgggattt catcaccaat aaacgccgag aggatcttcg
     1681 cactgcgggt gacaaaatcc agcttcagca tctcatcaat ttcagtcagg ctgaattccg
     1741 gcaggtcatg cggaaaaaac agcccctgat ttttgcccaa cccctgggtt acggcttgcg
     1801 caaagctgac ctgctcgttg tgatctttca gattgtagag tttcatttag ttttccagta
     1861 ctcgtgcgcc cgccgtatcc agccggcaaa tatgaacaaa accttcctga ttttgcaggt
     1921 agttcttacc caaccagtcg gcaacgcgct gggcggtatc cggcttgtca catagagcga
     1981 acaaggtcgg gccggagccg gagataccgc tcgctaccgc gccgatttcc gcgaccgcct
     2041 gccgcgcctg ccggaagcca ggcagtaacc gttcacggta gggttcagcg ataacatctt
     2101 tcatcagctt cgcggcaagc tcaggctgac gggaatagca ggcgtgaatg aagccagcca
     2161 gatgtcgccc gtgcgcaatg caatcctggc ggcgatactg cgccggtaaa atagccctgg
     2221 cttctgccgt cgagacttta atccccggat acgccagcac ccacagccac tcatcaaacc
     2281 ctggcacttg ctggctgatg atgtcgtttt cttcgatcat caactgcata ccaccaagaa
     2341 aacacggtgc cacgttgtcg taatgaatgc tgccggagat tcgtccttcc agctcgccca
     2401 tcaaagccag caaacgagtg tcattaagcg gcttgccaca gtgttcattc atcgccatca
     2461 gcgccgcgac caccgaacag gcgctggagc ctaagcccga accgattggc atattctttt
     2521 ccagagtcat cgccactgga atttgcttgc caagctcctg gcaaaaacgc tcccagcact
     2581 gataaacgat attttcccgt ggttctgacg gcagcttatc ggcaaagcgt ccgaggttgt
     2641 tgagactgaa tgtctctgcc gcctcaaccg tgactacatc tccgagcaat gcaccatcaa
     2701 caggtgtcac cgccgccccg agcacatcaa acccgacgct catattggca ctggaagccg
     2761 gggcataaac tttaaccatg tcagactcct aacttccatg agagggtacg tagcagatcg
     2821 gcaaagacac cggcagctgt aacgtcattg cccgcaccat atccgcgcag caccaacggc
     2881 agcggctgat aatagtggct ataaaaggcc agggcgtttt cgccattttt cactttgaac
     2941 agcggatcat taccatccac ttcggcaatc ttcacgcggc aggcaccatc ttcatcaata
     3001 ttgccaacat agcgcaaaac ttttccttca tcacgggcct tcgccacgcg cgcggcaaag
     3061 agatcgtcga gctgtgacag attcgccata aaagcggcaa catcaccctc agcgttaaac
     3121 tctgcgggca gcacaggttc aatttcaata tccgccagct ccagttcacg tcccgtttca
     3181 cgagcgagaa tcaatagctt acgcgctaca tccataccag aaagatcatc tcgcggatcc
     3241 ggttcggtat aacccatttc ccgcgccaga gtagtcgcct cggagaaact catgccttcg
     3301 tctaacttgc cgaagatata agaaagcgaa cctgaaagaa tgccggagaa cttcatcaat
     3361 tcatcaccag cattgagcag attttgcagg ttctcaataa ccggtaatcc agccccaacg
     3421 ttggtgtcat agaggaattt acgccgcgat ttttccgccg catgacgcaa cagatggtag
     3481 taatccatcg acgaggtgtt ggcctttttg ttcggcgtga caacgtggaa accttcgcgc
     3541 aagaagtcgg catattgatc cgccactgcc tggctggagg tgcagtcaac aatgaccggg
     3601 ttcagcagat gatattcttt cacgaggcga attaagcgcc cgagattaaa cggctctttg
     3661 gcttgcgcca gttcttcctg ccagttttcc agatttaggc catgcacatt ggtgagcagt
     3721 gccttcgagt tggcaacacc gcagacacgt aagtcgatat gtttattctt cagccagctt
     3781 tgttgacgct tcagttgctc cagcagcgca ccgccaacgc caccgacgcc aatcacaaac
     3841 acttcgataa cctgatcggt attgaacagc atctgatgag taacgcgcac gccagtggtc
     3901 gcatcatcgt tatttaccac gacagagatt gagcgttcag aagatccctg agcaatggcg
     3961 acaatgttga tattggcgcg ggccagcgcg gcaaagaatt tcgccgagat cccacgcaag
     4021 gtgcgcatac catcacctac caccgagata atggccagcc gttccgtcac cgccagcggc
     4081 tccagtaagc cttctttcag ttccaggtag aactcttcct gcattgcccg ttcagctcgc
     4141 acacagtcgc tttgtggaac gcagaaactg atactgtatt cggaagatga ttgcgtaatc
     4201 agcaccacgg aaatacgggc gcgtgacatc gcggcaaaga cgcgcgccgc catgccgacc
     4261 attcctttca tccccgggcc ggaaacgctg aacattgcca tgttattcag attggaaatg
     4321 cccttgaccg gtaattcgtc ttcatcacga ctggcaccaa tgagcgtacc tggtgcttga
     4381 ggatttccgg tatttttaat caggcaaggg atctggaact gggcgatggg ggtaatggtg
     4441 cgggggtgaa gaactttagc gccgaagtag gaaagctcca tcgcttcctg gtaggacatc
     4501 gacttcaaca acctcgcatc gggcacctga cgcgggtcgc aggtatagac cccgtcaacg
     4561 tccgtccaaa tctcgcaaca atcggcgcgt aaacaggcag ccagcaccgc cgcggagtag
     4621 tcggaaccgt tgcgtccaag taccaccagt tcgccttttt cattaccggc ggtgaaacct
     4681 gccatcaaca ccatgtgatc agccggaatg cggcttgccg caatacggcg ggtggactca
     4741 gcaatatcga cggtagattc gaggtaatgc cccactgcca gcagtttttc gaccggatcg
     4801 ataacggtaa cgttgtgacc acgcgcttct aacacgccgg ccataatggc gatcgacatt
     4861 ttctcgccac ggcaaatcag cgcagcgttg atgctctccg ggcactgccc caacaaacta
     4921 atgccatgca ggacatgttt tatttgggca aattcctgat cgacgaaagt tttcaattgc
     4981 gccagcggga accccggctg ggcggcggcg agtcccgtca aaagttcggc aaaaatacgt
     5041 tcggcatcgc tgatattggg taaagcatcc tggccgctaa tggttttttc aatcatcgcc
     5101 accaggtggt tggtgatttt ggcgggggca gagaggacgg tggccacctg cccctgcctg
     5161 gcattgcttt ccagaatatc ggcaacacgc agaaaacgtt ctgcatttgc cactgatgta
     5221 ccgccgaact tcaacactcg catggttgtt acctcgttac ctttggtcga aaaaaaagcc
     5281 cgcactgtca ggtgcgggct tttttctgtg tttcctgtac gcgtcagccc gcaccgttac
     5341 ctgtggtaat ggtgatggtg gtggtaatgg tggtgctaat gcgtttcatg gatgttgtgt
     5401 actctgtaat ttttatctgt ctgtgcgcta tgcctatatt ggttaaagta tttagtgacc
     5461 taagtcaata aaattttaat ttactcacgg caggtaacca gttcagaagc tgctatcaga
     5521 cactcttttt ttaatccaca cagagacata ttgcccgttg cagtcagaat gaaaagctga
     5581 aaaatactta ctaaggcgtt ttttatttgg tgatattttt ttcaatatca tgcagcaaac
     5641 ggtgcaacat tgccgtgtct cgttgctcta aaagccccag gcgttgttgt aaccagtcga
     5701 ccagttttat gtcatctgcc actgccagag tcgtcagcaa tgccatgact cgttcgcgta
     5761 aagcttgcag ttgatgttgg tctgccgttg tgtcactttt cgccggttgt tgtattaatg
     5821 ttgctaattg atagcaatag accatcaccg cctgccccag attgagcgaa ggataatccg
     5881 ccaccatcgg cacaccagta agaacgtcag ccaacgctaa ctcttcgtta gtcagcccgg
     5941 aatcttcgcg accaaacacc agcgcggcat ggctcatcca tgaagatttt tcctctaaca
     6001 gcggcaccag ttctactggc gtggcgtagt aatgatattt cgcccgactg cgcgcagtgg
     6061 tggcgacagt gaaatcgaca tcgtgtaacg attcaaccag tgtcgggaaa actttaatat
     6121 tatcaataat atcaccagat ccatgtgcga cccagcgggt ggctggctcc agatgtgcct
     6181 gactatcgac aatccgcagt tcgctaaaac ccatcgtttt cattgcccgc gccgctgccc
     6241 caatattttc tgctctggcg ggtgcgacca gaataatcgt tatacgcata ttgccactct
     6301 tcttgaccaa ataaccgcga acagggtgat cactgtcaac ttattacgcg gtgcgaattt
     6361 acaaattctt aacgtaagtc gcagaaaaag ccctttactt agcttaaaaa aggctaaact
     6421 atttcctgac tgtactaacg gttgaattgt taaaaaatgc tacatatcct tctgtttact
     6481 taggataatt ttataaaaaa taaatctcga caattggatt caccacgttt attagttgta
     6541 tgatgcaact agttggatta ttaaaataat gtgacgaaag ctagcattta gatacgatga
     6601 tttcatcaaa ctgttaacgt gctacaattg aacttgatat atgtcaacga agcgtagttt
     6661 tattgggtgt ccggcccctc ttagcctgtt atgttgctgt taaaatggtt aggatgacag
     6721 ccgtttttga cactgtcggg tcctgaggga aagtacccac gaccaagcta atgatgttgt
     6781 tgacgttgat ggaaagtgca tcaagaacgc aattacgtac tttagtcatg ttacgccgat
     6841 catgttaatt tgcagcatgc atcaggcagg tcagggactt ttgtacttcc tgtttcgatt
     6901 tagttggcaa tttaggtagc aaacatgcag accccgcaca ttcttatcgt tgaagacgag
     6961 ttggtaacac gcaacacgtt gaaaagtatt ttcgaagcgg aaggctatga tgttttcgaa
     7021 gcgacagatg gcgcggaaat gcatcagatc ctctctgaat atgacatcaa cctggtgatc
     7081 atggatatca atctgccggg taagaacggt cttctgttag cgcgtgaact gcgcgagcag
     7141 gcgaatgttg cgttgatgtt cctgactggc cgtgacaacg aagtcgataa aattctcggc
     7201 ctcgaaatcg gtgcagatga ctacatcacc aaaccgttca acccgcgtga actgacgatt
     7261 cgtgcacgca acctgctgtc ccgtaccatg aatctgggta ctgtcagcga agaacgtcgt
     7321 agcgttgaaa gctacaagtt caatggttgg gaactggaca tcaacagccg ttcgttgatc
     7381 ggccctgatg gcgagcagta caagctgccg cgcagcgagt tccgcgccat gcttcacttc
     7441 tgtgaaaacc caggcaaaat tcagtctcgt gctgaactgc tgaagaaaat gaccggccgt
     7501 gagctgaaac cacacgaccg tactgtagac gtgacgatcc gccgtattcg taaacatttc
     7561 gaatctacgc cggatacgcc ggaaatcatc gccaccatcc acggtgaagg ttatcgcttc
     7621 tgtggtgatc tggaagatta atcggcttta ccaccgtcaa aaaaaacggc gctttttagc
     7681 gccgttttta tttttcaacc ttatttccag atacgtaatt gatcgtccat tgtaacttct
     7741 ttactggctt tcattttcgg cagtgaaaac gcataccagt cgatattacg agtcacaaac
     7801 atcatgccgg ccagcgccac caccagcaca ctggttccca acaacagcgc gctatcggca
     7861 gagttgagca gtccccacat cacaccatcc agcaacaaca gcgcgagggt aaacaacatg
     7921 ctgttgcgcc agcctttcaa taccgcctgc aaataaatac cgttcattaa cgccccaatc
     7981 agactggcga ttatccatgc cacggtaaaa ccgatatgtt cagaaagcgc cagcaagagc
     8041 aaataaaaca ttaccaatga aagccccacc agcaaatatt gcattgggtg taaacgttgc
     8101 gcggtgagcg tttcaaaaac aaagaacgcc ataaaagtca gtgcaatcag cagaatggcg
     8161 tacttagtcg cccggtccgt taattggtat tgatcggctg gcgtcgtcac tgcgacgcta
     8221 aacgcgggga agttttccca gccggtatca ttgcctgaag caaaacgctc accgagatta
     8281 ttagcaaacc agctgctttg ccattgcgcc tgaaaacctg actcgctaac ttcccgtttg
     8341 gctggcaaaa aatcacctaa aaaactggga tgcggccagt tgctggttaa ggtcatttcg
     8401 ctattacgcc cggcaggcac cacagaaaga tcgccggtac cgcttaaatt cagggccata
     8461 ttcagcttca ggttctgctt ccgccagtcc ccttcgggta aagggatatg cacgccctgc
     8521 ccgccttgct ctaacccggt accgggttca atggtcagtg ccgttccgtt aacttcaggc
     8581 gctttcacca caccaatacc acgcgcatcc ccgacgctaa tcacaataaa gggcttgcct
     8641 aagatgatat ttggcgcatt gagctcgcta agacgcgaaa catcgaaatc ggcttttagc
     8701 gttaaatcac tgtgccagac ctgaccggta taaatcccta tcttgcgttc ttccacgttc
     8761 tgattgccat caaccatcaa tgactcaggt aaccaaaaat ggataaaact tcgtttccgc
     8821 tccacggttt tatcctcttc ctgcaccgta taaagctcgg tcacaggaat agcgataagc
     8881 ggcccaacga gtttttgcgg cccgctggta ctttggcgaa tcgcatcttc cacatcgcta
     8941 cggtaatcgg cacgttcgac aatcacctgc cgaatcagca ttatcggaat caacaacagc
     9001 aatactgcac caaacagggt ggtcattttc cagaacaggg gggatttcaa catagtcttc
     9061 tcctttgcaa tggcagcagg atacgaaggc tatgtgggaa gaatttgaag ctatgtgaag
     9121 tgacggtgaa gtcgaagcga ggccagcacg ccaccttcct gcacgttgcg cagcgtgact
     9181 tcgccgttaa acaaacgggc gacctcactg acgaacgcca accccagacc gctgcttttt
     9241 tgcccatttg cacgcggcaa agagtaaaag cgttcaaaaa tacgtgacag cgcgtagtca
     9301 ggaataccac taccggtatc cagcacctta agcgtgacgt gttcctgatc cacttcggcg
     9361 cttagcgtta tacgaccgct ctcgggggta aaatcgatgg cgttatccag taaattcccc
     9421 agcgcctgat ccagtaacgc cggttcagca gcaacattaa cctcggtggg cgtaacatgt
     9481 agagtgatgt ttttttctgc caactgcacg gtgcgcgctt cgctgacgcg gcggaataat
     9541 gccgccacat caacagcagt caaaacgact tcctgacgat tctccagtct tgcctggcgt
     9601 agtaacgttt ccaccagtgc ctgcattcgc gcattttgcg tcagaatgtt gtcagtaaaa
     9661 cgagccacta cttcaggcgg cggaccttcg cgtaaaattt ccgccgcgcc acgaatcgcc
     9721 gccagtgggc tttttagctc atgggttaac gcataaacat actgctcaat atagtttttc
     9781 ccttccagct tcacgcgcat actttccagc gcctgcgcga gtttacgcag ctcgctacta
     9841 ccgagatcgg gaagaggaac gggcttattg tcagtgacgg aatcagcata gcgagtgagc
     9901 cgggcaatgg agcggttgat ccaccaaacc atgcctgcgc caatcaccag tgcgatcccc
     9961 aacaaaatgg cgctggccca taaaattcgc cgctcgctgc gtttaatgac cggagccatc
    10021 gccgcgttcg gtttgcctac gctcaaaacg ccaataagcc gcgagccgtc cataatcggc
    10081 gcggcaacat acatcaccga actttcggga tcggcaggat tttgcaacgt gctgcgcgca
    10141 ccatactgac cacgcaacgt tagccagacg tcattccagc gcgaataatc ctgcccaacg
    10201 gctttatttg ccgaatcgaa caatacttta ccctgcgaat cggtcatata gacatgatat
    10261 tcattgcgca ctttgttaat gccaccgata ttggcgcgaa acgggcgatg ttgtagctga
    10321 ttaaacgcct gcgccagttg cccatgcgtt gggtccccag agagcaaatc gggacgcgcc
    10381 agctccgcca gcaacgttgc ggtgtcgatc aacgtcccct ccgttgctct tcgcacgccc
    10441 ggtttaactt ctttgacaaa aatagccagt acgaaccagg ccgccaccgc caccagtaaa
    10501 aaatagccca gcagcaaccg catgccgata cgcattacag gcccctcagg ctatatccca
    10561 tgccgcgatg agtattaatc ggtgaaagat cggggttgat ggcgcgcagc ttggcacgca
    10621 acgttttaat gtgggtatca acggtgcgat cgtaggtgtc ctgcgcatct tcccacacgc
    10681 tatccatcag ttgctggcgg gaccagacgc ggcctggcga cttgagtaac gtcttcagca
    10741 ataaaaactc ataccgcgtc agcgttaatg gcgtgtcaaa ccagctgatc tgcgccgcgg
    10801 gttcattcaa ttcaaaatga ccaatacgga tgacgggaga cggcgacgag aacttcttca
    10861 cccgacgcag taaggtgcgc accctggcgc acacttcgcg gggtgaaaac ggtttagcca
    10921 catagtcgtc agcgccaatt tccagcccaa gcaggcgatc gacctcttca cttcgggccg
    10981 tcaggaacag tacaggtaac gccggatgga gcgccagtaa ctggcggcac aattcaaagc
    11041 cactgatatc aggcaaacca acgtcaagaa tcatgacgtc gggaacctgc tggcgagctt
    11101 tatccagcac cggcaaacct cgctcaaaga cctcgacggc aaaaccttcc tgctgcaaca
    11161 tgtagaccag cgtgtcggct atcccttgct catcttccac taaccagacc gtttcccgtt
    11221 gcataaatcg cctctgttat tgccgccacg gcatgacagg aaccgcgcta atcgcgtttt
    11281 tcggcgaacc ttctacaact ttgtcggagt aagccagata agcgagcgcg ttgcgtttgg
    11341 cgtcataaaa gcgcacgacc tgtaacgact taaagaccag ggacgtgcgt tttttgaata
    11401 ctacctcgcc ctgagctttg ccgtttttaa tacgatccga cagttcaatc ggcccgactt
    11461 gctgacaaga aatggccgca tcggaggtat cttctgccag gcccaatccc cctttaatac
    11521 caccggtttt cgcccggctc acataacagg tgacattttt cacatcggga tcgtcaaagg
    11581 cttccacaac aattttgtga tccgggccga tcattttaaa tacggtgtcg accgaaccaa
    11641 tctcttctgc atgagccaat ggccccagca ttatcaggct taaagacagg atcaaatgct
    11701 tgtatttcat attgttacca tttttatcta ttacacgagc aattagttcg tcacggtaaa
    11761 taacatattg attaagaaca aaatctcaat acttttattt ccgtcaagcc ctaaa
//
LOCUS       DAZUDJ010000112        11749 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.113, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000112 DAZUDJ010000000
VERSION     DAZUDJ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11749
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.113"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..201
                     /locus_tag="ACHY1N_004539"
     CDS             <1..201
                     /locus_tag="ACHY1N_004539"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046720.1"
                     /translation="KRKAISHDGLFALAQKKMPDATLRVLYSHICQIQQRIRLPQLAH
                     FHTCPPYQKFILKLLNNHFPAN"
     gene            318..1616
                     /gene="kgtP"
                     /locus_tag="ACHY1N_004540"
     CDS             318..1616
                     /gene="kgtP"
                     /locus_tag="ACHY1N_004540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoglutarate permease"
                     /protein_id="HFS4046721.1"
                     /translation="MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFC
                     SLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCM
                     MCFGSLVIACLPGYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGF
                     YASFQYVTLIGGQLLALLVVVVLQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQL
                     DETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGM
                     HANVASGIMTAALFVFMLIQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVS
                     SPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYV
                     ALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL"
     gene            complement(1613..1936)
                     /gene="yfiM"
                     /locus_tag="ACHY1N_004541"
     CDS             complement(1613..1936)
                     /gene="yfiM"
                     /locus_tag="ACHY1N_004541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HFS4046722.1"
                     /translation="MRILFVCSLLLLSGCSHMANDSWSGQDKAQHFIASAMLSAAGNE
                     YSQHQGMSRDRSAMFGLMFSVSLGASKELWDSRPEGSGWSWKDLAWDVAGASTGYTVW
                     QLTRH"
     gene            complement(1982..3337)
                     /gene="pssA"
                     /locus_tag="ACHY1N_004542"
     CDS             complement(1982..3337)
                     /gene="pssA"
                     /locus_tag="ACHY1N_004542"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HFS4046723.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKI
                     ASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLF
                     RQELRDAAYHFQGDADNDQLSVTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNL
                     PAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHD
                     PQLELAPQREKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            complement(3451..6111)
                     /gene="pat"
                     /locus_tag="ACHY1N_004543"
     CDS             complement(3451..6111)
                     /gene="pat"
                     /locus_tag="ACHY1N_004543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HFS4046724.1"
                     /translation="MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVLAWPDIASLPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSA
                     PASQHEDLRACALRHNMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVS
                     NTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLRGDRLMIISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPGHV
                     AISNPLDLRDDASSEHYIKTLDILLHSQDFDALMVIHSPSAAAPATESAQVLIEAVKH
                     HPRSKYVSLLTNWCGEHSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHLLLQQAIAEGATSLDTHEVQPILQAYGMNTLPTWIASDSTE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTANEVQQAANAIFDRVKMAWPQA
                     RVHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEDQAVVALPPLNMN
                     LARYLVIQGIKSKKIRARSALRPLDVAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASG
                     SEFTALDVTLDISPFEGDNESRLAVRPYPHQLEEWVELKNGERCLFRPILPEDEPQLQ
                     QFISRVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRIDQTEEILGVTR
                     AISDPDNIDAEFAVLVRSDLKGLGLGRRLMEKLITYTRDHGLQRLNGITMPNNRGMVA
                     LARKLGFNVDIQLEEGIVGLTLNLAQREES"
     gene            complement(6143..6841)
                     /gene="tapT"
                     /locus_tag="ACHY1N_004544"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
     CDS             complement(6143..6841)
                     /gene="tapT"
                     /locus_tag="ACHY1N_004544"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
                     /EC_number="2.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417078.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="HFS4046725.1"
                     /translation="MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCS
                     TITPAQAKSRFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSQDLLELVQNP
                     DYQPMVVFPASYADEQREVIFTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDNLPVIS
                     VDLSRLSAYRLREAQAAGQYCTAEVAIALLDMASDTGAAAGLGEHFTRFKTRYLAGKT
                     QHLGSITAEQLESV"
     gene            complement(6910..7329)
                     /gene="trxC"
                     /locus_tag="ACHY1N_004545"
     CDS             complement(6910..7329)
                     /gene="trxC"
                     /locus_tag="ACHY1N_004545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA];
                     GO_process: GO:0006662 - glycerol ether metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HFS4046726.1"
                     /translation="MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRF
                     GIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL"
     gene            7536..8573
                     /gene="yfiF"
                     /locus_tag="ACHY1N_004546"
     CDS             7536..8573
                     /gene="yfiF"
                     /locus_tag="ACHY1N_004546"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HFS4046727.1"
                     /translation="MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRA
                     DGGRRPARDDKQSQPRDRKWEDSPWRTVSRAPGDETPEKADHGGISGKSFIDPEVLRR
                     QRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSC
                     AHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS
                     SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGV
                     LLGEWWRQNKA"
     gene            complement(8621..9310)
                     /gene="ung"
                     /locus_tag="ACHY1N_004547"
     CDS             complement(8621..9310)
                     /gene="ung"
                     /locus_tag="ACHY1N_004547"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFS4046728.1"
                     /translation="MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPG
                     FTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPI
                     DWMPVLPAESE"
     gene            9615..9998
                     /gene="grcA"
                     /locus_tag="ACHY1N_004548"
     CDS             9615..9998
                     /gene="grcA"
                     /locus_tag="ACHY1N_004548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007728348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HFS4046729.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVV
                     AVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            complement(10054..10641)
                     /gene="eamB"
                     /locus_tag="ACHY1N_004549"
     CDS             complement(10054..10641)
                     /gene="eamB"
                     /locus_tag="ACHY1N_004549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HFS4046730.1"
                     /translation="MTPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLA
                     GMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQA
                     KPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCW
                     ALAGHLFQRLFRQYGRQLNIVLALLLVYCAVRIFY"
     gene            10744..11625
                     /gene="yfiE"
                     /locus_tag="ACHY1N_004550"
     CDS             10744..11625
                     /gene="yfiE"
                     /locus_tag="ACHY1N_004550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417072.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4046731.1"
                     /translation="MDLRRFITLKTVVEEGSFLRASQKLCCTQSTVTFHIQQLEQEFS
                     VQLFEKIGRRMCLTREGKKLLPHIYELTRVMDTLREAAKKESDPDGELRVVSGETLLS
                     YRMPQVLQRFRQRAPKVRLSLQSLNCYVIRDALLNDEADVGVFYRVGNDDALNRRELG
                     EQSLVLVASPQIADVDFTEPGRHNACSFIINEPQCVFRQIFESTLRQRRITVENTIEL
                     LSIESIKRCVAANIGVSYLPRFAVEKELESGELIELPFGEQSQTITAMCAHHAGKAVS
                     PAMHTFIQCVEESFVAG"
BASE COUNT         2921 a         2935 c         3039 g         2854 t
ORIGIN      
        1 aagcgaaagg ccatcagtca cgatggcctt tttgcgttgg cgcagaaaaa aatgcctgat
       61 gcgacgctgc gcgtcttata ctcccacata tgccagattc agcaacgaat acggcttccc
      121 caacttgctc acttccatac gtgtcctcct taccagaaat ttatccttaa gctcctcaat
      181 aatcattttc ctgctaacta aattcatggt taaggttgca taatgatatg caacaaatgt
      241 ataacatttt ctttaccaaa agaaataaac aaaagtgacc gacaaaagca tcggattacg
      301 gcaggagaca taatggcatg gctgaaagta ctgtaacggc agacagcaaa ctgacaagta
      361 gtgatactcg tcgccgcatt tgggcgattg tgggggcctc ttcaggtaat ctggtcgagt
      421 ggttcgattt ctatgtctac tcgttctgtt cactctactt cgcccacatt ttcttccctt
      481 ccgggaacac gacgactcaa ctactacaaa cagcaggtgt ttttgctgcg ggattcctga
      541 tgcgcccaat aggcggttgg ctatttggcc gcatagccga taaacatggt cgcaaaaaat
      601 cgatgctgtt atcggtgtgt atgatgtgtt tcggatcgct ggttatcgcc tgcctcccag
      661 gttatgaaac tataggtacg tgggctccgg cattattgct tctcgctcgt ttatttcagg
      721 gattatccgt tggcggagaa tatggcacca gcgccaccta tatgagtgaa gttgccgttg
      781 aagggcgcaa aggtttttac gcatcatttc agtatgtgac gttgatcggc ggacaactgc
      841 tagccctact ggttgtcgtg gttttacaac acaccatgga agacgctgca ctcagagagt
      901 ggggatggcg tattcctttc gcgttaggag ctgtgttagc tgttgtggcg ttgtggttac
      961 gtcgtcagtt agatgaaact tcgcaacaag aaacgcgcgc tttaaaagaa gctggatctc
     1021 tgaaaggatt atggcgcaat cgccgtgcat tcatcatggt tctcggtttt accgctgcgg
     1081 gctccctttg tttctatacc ttcaccactt atatgcagaa gtatctggta aatactgcgg
     1141 gaatgcatgc caacgtggcg agtggcatta tgactgccgc attgtttgta ttcatgctta
     1201 ttcaaccact cattggcgcg ctgtcggata agattggtcg ccgtacctca atgttatgtt
     1261 tcggttcgct ggcagccatt tttaccgttc ctattctctc agcattgcaa aacgtttcct
     1321 cgccttatgc cgcttttggt ctggtgatgt gtgccctgct gatagtgagt ttttatacat
     1381 caatcagtgg aatactgaag gctgagatgt tcccggcaca ggttcgcgca ttaggcgttg
     1441 gtctgtcata tgcggtcgct aatgctatat ttggtggttc ggcggagtac gtagcgttgt
     1501 cgctgaaatc aataggaatg gaaacagcct tcttctggta tgtgaccttg atggccgtgg
     1561 tggcgtttct ggtttctttg atgctacatc gcaaagggaa ggggatgcgt ctttagtgac
     1621 gggtcagttg ccagacggta tagccggtgc ttgcaccggc gacatcccag gccaaatcct
     1681 tccagctcca gccgctccct tcggggcggc tatcccaaag ctcttttgac gcccccaaac
     1741 tgacagagaa catcaatcca aacatggcac tgcgatcccg gctcatcccc tgatgctgtg
     1801 aatattcatt tccggcggcg gaaagcatcg ccgaggcgat aaagtgttga gctttatcct
     1861 gcccgctcca gctatcgtta gccatatggc tgcatccaga aagtaacaat agcgaacaga
     1921 caaaaagaat acgcaaaacg tggcctccaa aaaacaaacc ccgtacagga cggggttgtg
     1981 attacaggat gcggctaatt aatcggtcga tgcggatacg gcgcaaacgg cggatgagtt
     2041 tacgaacctt caccggataa tcggcaatac tttgcagatc gcgatagtgc ttaacgatgg
     2101 tggtatgctc gcggatcagc tccagttctt tctctcgctg cggcgcaagc tccagttgtg
     2161 gatcgtggat caaaatggcg ttttccagat ccagacgcca ggcgcgcggg ttcaggttat
     2221 taccggtgat caacatccac ttatcatcaa cccacatccc ttttaggtga taggtgttgt
     2281 cgtcatcttt ccataaccga accactagct ggtcagtatt gacgtaatac tgcaaacggc
     2341 tcaggaaacg acgcagattg atctcataga gataaggcaa tgcgccaatt atcttgaaag
     2401 gttcatcttc cggaatgtag aagtcgttcg cggttttatc accaacaata atttcgacct
     2461 ttttcccttc gcgcagcaac tggataatat tgcgcacaag gattgctggc aggttgaagt
     2521 atggcgtaca gatggttagt ttctgctcgg cacaaggcat aagatggaaa atggtcttgt
     2581 tcaacagact cgatttcccc agccccacta gcggcgttac ggaaagctga tcgttgtcgg
     2641 catcgccctg gaaatgataa gcggcatcac gcagctcctg gcggaacaga cgaatatcgt
     2701 tcttgatttc cgggcttttt ggccgattaa catcatccag acgattaacg ccgcggccat
     2761 tcataatatt ctgtgtaacc cattcaaaca taatgtctga catcttacgg ttacggatca
     2821 gatgataacg gtcgtagcga tatttatcgt gctgatgcag gtaaacatcg ttcaggctgg
     2881 caccgctata aagtacgcta tcgtcgatga taaagccttt aaagtgcaga acaccaaggg
     2941 cttcacgggt attgattgga acgccataaa ccggaacatc tacgcccgga ttttcctgcg
     3001 ccatgcggca gtaccagtca gcgttagtgt tagatgccgc agcgccaatg cgtccacgtt
     3061 gtgcacgatg ccagtcgacc agcacccgca catccagttc cggacgctgc cttttagctt
     3121 catacaacgc gttcagaatg cctttgccac cgtcatcctg ttcgagatac agggcgacaa
     3181 tgcaaatgcg ctgcttcgcg ctggctattt tttccagcag cgtctcccgg aagtcggcgg
     3241 gagcgtaaaa gaaatcgaca tcatcaactg attgagaaat cttgggtagt tgggcaaggt
     3301 gttgttgatg tttattacgc ttaaattttg acaacatcac agtgcatttc ttctctgttc
     3361 attgaagggt cctctgtgca atgcagacga cataagcggg caataataac accagtcccg
     3421 attaagtggt caacatttcc agtaccttac tcatgattcc tcgcgttggg caagatttag
     3481 cgtaagccca acgatcccct cttcgagctg gatatcaacg ttaaacccga gcttgcgggc
     3541 tagcgccacc atgccacgat tgtttggcat cgtaatacca ttcagacgtt gtagtccgtg
     3601 atctcgcgta taggtaatca acttttccat taagcgtcga cctaagccta accctttgag
     3661 atccgagcga accagcacag caaattcggc atcgatgtta tcaggatcgg aaatcgcacg
     3721 cgtgacgccg aggatctctt ccgtttgatc aatacgtcgt accgctacaa acgccatttc
     3781 ccgatcgtag tcgatctgtg tcatgttggc taaatcttca tgggtaaatt cgttgatctc
     3841 gctaaagtag cggtaataaa gatcttcttt ggtgactcgc gaaatgaatt gctgaagttg
     3901 tggctcatct tctggcaaaa tcgggcggaa caagcagcgt tcaccgtttt tcaattctac
     3961 ccattcttcc agctgatgcg gataagggcg cactgccagc cgactctcgt tatcgccttc
     4021 aaacggcgag atatccagcg tgacatccag cgcggtaaat tcactgccag aagccagcaa
     4081 aggatgaata tccagacgct gaatttccgg gcaatcgaca atcaagttgg aaacctgcac
     4141 cagaagctgg ctcaagcctg caacatccaa tgggcgtagc gcactgcgcg cacgaatctt
     4201 tttacttttg atcccctgaa taaccagata gcgggccagg ttcatgttca gcggcggcag
     4261 tgcgacgacg gcttgatctt caggacgcca ctccacaccg ccttcaccca gcatgatcaa
     4321 cggcccgaaa accggatcgt gctcaaccac aacccgcaac tcctgagcgc cagcacggtt
     4381 agccatactt tgcaccaaca ggccgtggac ccgcgcctgt ggccaggcca tttttacgcg
     4441 atcgaaaata gcgttcgccg cttgctggac ttcattggct gtacgcaggt aaagcatgac
     4501 gccctgaact tccgatttat gtggaatatc cggcgaacgc aatttcagcg ccaccggata
     4561 accaatctgt tcggcaatat gcaccgcttc ggtgctatcg ctggcaatcc aggtagggag
     4621 cgtgttcatg ccatacgctt gcaggatggg ctgaacttca tgggtatcga gcgacgtagc
     4681 cccttcggca atcgcctgtt gcaacagaag atgcgcttct gcggtattgg aagtcagatt
     4741 gctgggcaac gccggcgttt cgcgtagttg cttctgatta cgccggtact ccaccatatg
     4801 cataaaagca gtgatggttc cttccggggt acggtaggtc ggcagcccgg cttcgctgaa
     4861 taatcgtcgt gcctcttgcg aggaatgttc gccacaccag ttcgtcagca gagaaacata
     4921 cttgctgcgg ggatgatgct ttaccgcttc aattaatact tgcgcgcttt ctgttgcggg
     4981 agcagcggcg ctgggcgaat gaataaccat cagcgcatca aaatcctggc tgtggagcag
     5041 aatgtccagc gttttaatat agtgctcact gctggcgtca tcgcgcagat cgagcgggtt
     5101 agagattgcc acatgtcctg gcagtgcatc gcgcagtttc tggcaggttt cttcgcttag
     5161 cgttgccagc ttgccattgc gtgaccataa ggcatccagc gccagcgcgg caggcgcagc
     5221 accgttgctg ataatcatca accggtcgcc acgcagcggg cgcatatggc taagggtttc
     5281 caccgccgaa aacagttcgt gggtatcctg tacccgcaac aaaccggcac gctgaatagc
     5341 cgcatcccat gccgggtcca ttcctgccgt cgtgttgagc agtcgctgtg ccgccgggct
     5401 acgtccgctt ttaatcacca gaatcggttt attacgcgag gcactacggg ctgccgaaac
     5461 aaagcgtcgc gcgtcgctta actgttcgag atagagcagg atggcgctgg ttttactgtc
     5521 gcgcgccaga tagtcgagca attcatcaac gtcgatatcc aggctgtcgc cgagcgcaat
     5581 aaagtaggaa aagcccatct cacgctgttg cgcccagtcg aggatggtgt tggagacggc
     5641 tgccgattgt gaaataaacg ccagcttgcc gcgtttaatc ggcacaggcg aaaagctggc
     5701 attcagacct tgccagggag ccagtaaacc cagactgttt ggtccaagca ggcgcatgtt
     5761 atggcgcagg gcgcaggcgc ggagatcttc gtgttgcgat gccggggcgg aaagaataat
     5821 gcaggtttta cagcctttct cgccgagctc ttccagaaga gcaagattac ggctggcatt
     5881 ggtacataaa accgcaaggt cgggtgtaaa gggcaagctg gcaatatccg gccaggccaa
     5941 cacacccaac accgctttcc aggctggcgt caccgggagt accggtccgt taaagcctcc
     6001 cgccagcagg ttacgcatca tcaggtaacc tgcgcgattg ggtttcatcg acgcgccaat
     6061 taccgctatc gattttggtc gcagtagtgc ttccagtcct cgctgactca taccggtctc
     6121 ccgcagaagt gaccgaatga ttttaaacgc tttctaactg ttctgctgtg atgctaccca
     6181 gatgttgcgt ttttcctgcc agatagcgtg ttttaaagcg ggtaaaatgc tcgcctaacc
     6241 ctgctgccgc cccggtatcg ctggccatat ctaacagtgc gatggctacc tcggcagtac
     6301 aatattggcc tgcagcctgg gcttcacgca ggcgataggc agaaagccgg gaaagatcga
     6361 cggaaatgac gggaagatta tccagatacg gacttttacg aaacatcttg cgagcttccg
     6421 gccaggtacc atcgagcatg ataaacagcg gtggcttacc ggcaggtggt gtgaagatca
     6481 cttcccgttg ctcatcagca tacgaagcgg gaaagaccac cattggctga tagtccgggt
     6541 tttgcaccaa ctccagcaaa tcctgcgagg gttcggtacg cgaccattga aacgcaacgg
     6601 tatcaggcaa aatatcagca atcagacgcc cggtattact gggcttcatt ggctcggtgt
     6661 cgaacatcag caaacagaag cgactttttg cttgtgctgg ggtaattgtc gaacagagac
     6721 ataatttctc tggcaaaaga cagcgttggc agcgacgaac gcgattaccg cgggcaagaa
     6781 aaggacgtgt tgcgcgcgca atacgctcgg cgcgtaactg gagaacagcg ttttcggtca
     6841 taagagagcg tcgaaaaaac gccattgtcg cagaggagaa aacggggcac aagatgcgcc
     6901 ccggtaagat taaagagatt cgttcagcca gctatcgaac ggcgctttcg gtactgcgcc
     6961 attaagcatg tcgacaacct gaccgttttt gaaaatcatg atcgtcggta tactacgaat
     7021 tccaaagcga ctgctcaatt cacgttcagc ttcggtattc actttcacaa agcgcacttt
     7081 accgctacgc tcttgcgcga catcttcaaa aattggtgcg aaattacggc aggggccgca
     7141 ccacggtgcc cagaagtcga tcaccacagg tagatcatcc ttcagcaatt tgtcgagtgt
     7201 ttcaccggtc gcattaatca cctctccgtc aaacaagtcg tgaccgcagc gtccgcattt
     7261 tgccgcatct tcgatccgat cgtcgggaat gcgattgatg gcctgacaat gggtacaaac
     7321 ggtattcata actaacctcg ggatgagtaa ggagacttat cggcaacgac gccggtatgt
     7381 ttctaatatg ttacatatta tcggggacat tgttccagac aacaatctgt tttattcaat
     7441 aggtatgata gtcgcaggct ttggtacgaa atcatggcga accgcgcgga cttcgggtaa
     7501 tctgcgcgct tcgcgcagcg ctggtggaga aaagcatgaa cgatgaaatg aaaggtaaaa
     7561 gcggcaaggt caaagtgatg tatgtccgca gtgatgatga ttctgataaa cgtacccaca
     7621 acccgcgtac cgggaaaggg ggcgggcgtc caggaaaatc tcgtgctgac ggtggccgtc
     7681 gccccgcccg cgatgacaaa cagagtcagc cccgtgaccg caagtgggaa gattcgccgt
     7741 ggcgcacggt ttcccgcgcg ccgggtgatg agacgccgga aaaggccgat cacggtggca
     7801 tcagtggtaa aagttttatt gatccggaag tgttgcgtcg tcagcgtgcg gaagaaaccc
     7861 gcgtctacgg cgaaaatgca tgtcaggcac ttttccagag ccgtccggaa gcgattgttc
     7921 gcgcctggtt tatccagagt gtaacgccgc gttttaaaga agccttgcgc tggatggcag
     7981 caaaccgcaa agcgtaccat gtggtggatg aagcggaatt gacaaaagcg tcaggcacgg
     8041 aacatcacgg cggcgtttgc ttcctgatca aaaagcgtaa tggcacaacc gtgcagcagt
     8101 gggtaagcca ggcaggcgcg caggattgtg tactggcgct ggaaaacgaa tctaacccgc
     8161 ataacctggg tggcatgatg cgcagctgcg cgcacttcgg cgtgaaaggc gttgtggtgc
     8221 aggatgcggc actgctggag tcgggggcgg ctatccgtac cgcagaaggc ggcgcagagc
     8281 acgttcagcc gattactggc gacaacattg ttaacgtgtt ggatgatttc cgtcaggcag
     8341 gttacaccgt agtgaccact tccagcgagc aggggaaacc gctgttcaaa accagtctgc
     8401 cagcgaaaat ggtactggtg ctgggtcagg aatatgaagg gttaccggat gccgcacgcg
     8461 atccgaacga tctgcgcgtg aagattgacg gtacgggcaa cgttgccggg ctgaatatct
     8521 ctgttgcaac cggcgttttg cttggtgaat ggtggcgtca gaataaagcc tgataaatca
     8581 gccgggtggc aactctgcca tccggcattt taccgcaaat ttactcactc tctgccggta
     8641 atactggcat ccagtcaatc ggcgtctcgc cacgttgttc cagccactga tttgccagca
     8701 caaaatggtt gcagccaaag aatccacgat gcgccgaaag cggcgacgga tgcggtgctt
     8761 tcagtacatg atggcgttgc ttatctataa tcgccccttt cttttgcgca tgtgatcccc
     8821 acaacaaaaa caccacgcct tcgcggtgct ggttaatcag gctgatgact ttatcagtaa
     8881 acgtctccca accgaggctg gcgtgggaat gcgcctgacc tgcgcgaacc gtcaacacag
     8941 tattgagcag cagaacgccc tgacgcgccc agctttcgag atagccatga ttagggcggg
     9001 tgaagcccgg aatagtattt tccagctctt tatacatatt caataatgac ggaggaatgg
     9061 caatgccggg acgaacggaa aatgccagac catgcgcctg tcccggtccg tgataaggat
     9121 cctggccgag aatcaccact ttaacgtcac ccaactcggt aaagcggaac gcgttaaaga
     9181 catctttttg tggtggatag atagtgacgc cggactgccg ctcgctggcg acggtctgaa
     9241 gggtattaag aaaataaggt tgttgcttct cttcagccag cacgtcatgc caggttaatt
     9301 cgttagccat ctcgctctcc tgcgaatctt caatccgcct agcttaactg cttctttcta
     9361 cagaacaaaa tcatgctcat tttttagact taaacgagtg caaaaaaatg taaattggta
     9421 aaatttcaca cccgcataag ttgatgtaaa acaataaaat ccatttacga ccacaatcga
     9481 tgtgtggttt ttattgattt aaatcaaaga atcaagggtg gttgaggagt atatatacac
     9541 tcaagcaaca atggttttac caattggccg cgacaggctg aacaaatcaa ataattttgc
     9601 cggggaggca tcacatgatt acaggtatcc agattactaa agccgctaac gacgatctgc
     9661 tgaactcttt ctggctgctg gacagcgaaa aaggcgaagc acgttgcatc gttgcaaaag
     9721 caggttatgc agaagatgaa gtggttgcag taagcaaact gggtgacatt gaataccgtg
     9781 aagttccagt agaagtgaaa ccagaagttc gcgttgaagg tggtcaacac ctgaacgtta
     9841 acgttctgcg tcgtgaaact ctggaagatg cagttaagca tccggaaaaa tatccgcagc
     9901 tgaccatccg tgtatccggt tatgcagttc gctttaactc tctgactccg gaacagcagc
     9961 gcgacgttat cgctcgtacc tttactgaaa gcctgtaagg cttaagtagc aagttactaa
    10021 gcggaagagg gcgacctctt ccgctttttt tcgttaatag aaaatgcgta ccgcgcaata
    10081 gaccagcaac agggcaagca cgatatttaa ctggcgacca tactggcgaa acaatcgctg
    10141 aaacagatgc cccgccagcg cccagcacac attgccaaac gtcccaatca tcgccagcaa
    10201 aacgctgacg ccaactaccc agcttagcgc ctgtgtttgc ggcagaacaa acgtcgacag
    10261 tgccgtaaca ccgtacaaaa tgattttgac gttcacaaac tgcaaagcaa agctggccca
    10321 aaagctgatt ggttttgcct gaagtccgtc ttcctttgtt gggctggtgg cgattttcca
    10381 cgccagccag acaatatatg ccgcccccgc ccaactcaaa aggtgtaccg ctgccgggtc
    10441 aatcactgcc agtgaaaatg aaatgcccgc acacagtaac atcacaatca aaaatcccag
    10501 actcatccct gccagcacgc gggtactttg acgaaatcca tgcgacgtag cagagctaag
    10561 ggcgagaata ttgttcggtc ctggcgtcat agcggtaatc agggtgtaag tccaaaaagc
    10621 acttaaaagg gtcggtgtca cttgttatct cctctgtttt ggtagacagt acccgacacg
    10681 gaacatttaa aaaaatgaat gtttttatat tctagattcg atattttcga taggtttggg
    10741 gttatggatc tgcgccgttt tattacgctt aaaaccgtgg tggaagaggg ttcctttttg
    10801 cgagcttcgc aaaaattgtg ctgtacacaa tcgacggtga cttttcatat tcagcagctt
    10861 gagcaggagt tttcagtcca gttatttgag aaaattggcc gacggatgtg ccttacccgc
    10921 gaaggaaaaa agttgctgcc gcacatttat gaacttaccc gagtgatgga tacgcttcgt
    10981 gaggctgcca aaaaggagtc agatccggac ggggaactac gcgttgtttc gggcgaaacg
    11041 ttgctctctt accgaatgcc gcaggtgttg cagcgttttc ggcaacgcgc accaaaagtg
    11101 cgtttatcgt tgcagtcgct gaactgttac gtgatccgtg atgcgctact gaatgatgag
    11161 gccgatgtcg gcgtctttta tcgcgtaggg aatgatgatg ccctgaaccg acgagagttg
    11221 ggtgaacaat cgctggtgct ggtggcttca ccgcaaattg cagatgtcga ttttactgag
    11281 ccgggaagac ataacgcctg tagctttatt atcaacgaac cgcaatgtgt cttccggcag
    11341 atatttgaga gcacgctgcg tcagcggcgg atcacggtgg aaaacaccat tgagctgtta
    11401 agcattgaaa gtatcaaacg ttgtgtcgcg gcgaatatcg gtgtcagtta cttgccccgc
    11461 tttgcggtgg aaaaagagct tgagagcgga gaattaattg aattgccttt tggcgaacag
    11521 tcgcagacca ttacggccat gtgcgcacac catgctggaa aagcggttag cccggcgatg
    11581 cacactttta ttcagtgtgt tgaagagagt tttgtggctg gataaaaata atgtcgggat
    11641 taaacccggc atttaacttg tcgacaaagt gcgctttatt catgccggat gcggcgtgaa
    11701 cgccttatcc ggcctacaag atcgtgcaaa ttcaatatat tgcatgagc
//
LOCUS       DAZUDJ010000113        11584 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.114, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000113 DAZUDJ010000000
VERSION     DAZUDJ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11584
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.114"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..6935
                     /gene="yeeJ"
                     /locus_tag="ACHY1N_004551"
                     /pseudo
     CDS             1..6935
                     /gene="yeeJ"
                     /locus_tag="ACHY1N_004551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416485.4"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="inverse autotransporter adhesin YeeJ"
     gene            complement(7197..8249)
                     /locus_tag="ACHY1N_004552"
     CDS             complement(7197..8249)
                     /locus_tag="ACHY1N_004552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HFS4046732.1"
                     /translation="MFLASLLRRIAFSYYDYKAYNFNIEKTDFVVIHIPDQIGDAMAI
                     FPVIRALELHKIKHLLIVTSTINLEVFNALKLEKTKLTLVTMTMQDHATLKEIKDLAK
                     NITQKYGTPDLCIEAMRKKNLKTMIFISQLKAKTNFQVVGLTMKCYSPLCKNASRMDQ
                     NLRAPVPMTWAFMMREAGFPAVRPIYELPLSEDVLDEVREEMRSLGSYIALNLEGSSQ
                     ERTFSLSIAENLIAKIQSETDIPIVIVHGPKGEDKARVLVDCYNNVYRLSLSPSIKRS
                     AAIIKDAYIAITPDTSILHMASAYNTPVVAIYADYKTRWPAMADVSESVVVGQKIDNI
                     SLDEFAKALKSVLARI"
     gene            8564..9880
                     /gene="shiA"
                     /locus_tag="ACHY1N_004553"
     CDS             8564..9880
                     /gene="shiA"
                     /locus_tag="ACHY1N_004553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate transporter"
                     /protein_id="HFS4046733.1"
                     /translation="MDSTLISTRPDEGTLSLSRARRAALGSFAGAVVDWYDFLLYGIT
                     AALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVW
                     MMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKA
                     FYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNG
                     MEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNY
                     STQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGALIGTLSAFPFF
                     MALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVG
                     GGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDNQRA"
     gene            9982..11436
                     /gene="amn"
                     /locus_tag="ACHY1N_004554"
     CDS             9982..11436
                     /gene="amn"
                     /locus_tag="ACHY1N_004554"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008714 - AMP nucleosidase activity
                     [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0044209 - AMP salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HFS4046734.1"
                     /translation="MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGNYITSGELPDE
                     NARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLT
                     LLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETAD
                     GIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
BASE COUNT         3108 a         2831 c         2765 g         2880 t
ORIGIN      
        1 ggtaaacgcc gcaacccaac aaccagttcc tgcacaactc gccattgcaa atgccaatac
       61 ggtgccctac acccttggag cgctggaaat cggcccaaag cgttgccgaa cgtttcggta
      121 tttcggtggc tgagttacgc aaactcaacc agtttcgtac gtttgctcga ggttttgata
      181 atgtccgcca gggtgatgaa ctggatgtcc cggcacaagt tagtgaaaat aatttaaccc
      241 cgccaccggg taatagcagc ggcaaccttg agcaacagat agccagtact tcacagcaaa
      301 tcgggtctct gctcgccgag gatatgaaca gcgagcaagc ggcaaatatg gcgcgtggat
      361 gggcctcttc tcaggcttca ggcgcaatga cagactggtt aagccgcttc ggtaccgcaa
      421 gaatcacgct gggcgtggat gaagatttta gcctgaagaa ctcccagttc gattttctcc
      481 atccgtggta tgaaacgcct gataatctct ttttcagtca gcatactctc catcgtactg
      541 acgagcgtac acagattaac aacggcttag gttggcgtca tttcactccc acatggatgt
      601 cgggcatcaa cttctttttc gaccacgatc ttagccgtta ccactcccgc gccggcattg
      661 gcgcggagta ctggcgcgac tatctaaaat taagcagtaa cggctatttg cgactgacca
      721 actggcgcag cgcacctgaa ctggacaacg attatgaagc acgcccggcc aatggctggg
      781 atgtacgcgc agaaggctgg ctacccgcct ggccgtacct tggcggtaaa ctggtctatg
      841 aacagtatta tggcgatgaa gtggccctgt tcgataaaga cgatcggcaa agtaatcctc
      901 atgccataac cgctggactt aactataccc ccttcccgct aatgaccttc agcgcggagc
      961 aacgccaggg taaacagggc gaaaatgaca cccgttttgc cgtcgatttt acctggcaac
     1021 ctggcagcgc aatgcagaaa cagcttgacc cgaatgaagt cgctgcacgg cgtagccttg
     1081 caggcagccg ttatgatctg gtggatcgca acaacaacat cgttctggaa tatcgcaaaa
     1141 aagaactggt ccgcctgacc ctgacagacc ccgtgacagg gaagtcagga gaagtgaaat
     1201 cactggtttc gtcgctacaa accaaatatg ccctgaaagg ctataacgtc gaagccaccg
     1261 cactggaagc tgccggtggc aaagtggtca caacgggtaa agatattctg gttaccctgc
     1321 cgggttaccg gttcaccagt acgccagaaa ccgataacac ctggccgatt gaagtcaccg
     1381 ctgaagatgt caaaggcaat ttgtcgaatc gtgaacaaag catggtggtc gttcaggcac
     1441 ctacgctaag ccagaaagat tcctcggtat cgttaagtac ccaaacattg aacgcggatt
     1501 cccattcaac cgccacactg acttttattg cgcatgatgc agcaggtaat cctgttgtcg
     1561 ggctggtgct ctcgacgcgt cacgaaggtg ttcaggacat caccctttct gaatggaaag
     1621 ataatggtga cggaagctat acccagatcc tgaccacagg agcgatgtct ggcacgctga
     1681 cgctgatgcc acagctgaat ggtgtggatg cggctaaagc ccccgccgtg gtgaatatca
     1741 tttctatttc gtcatcccga actcactcgt caattaaaat tgataaagac cgttatctct
     1801 ccggcaatcc tatcgaggtg acggtagaac tgagagatga aaatgacaaa cctgttaagg
     1861 agcaaaaaca gcaactgaat aacgcagtca gcatcgacaa cgtgaaacct ggtgtcacta
     1921 cagactggaa agaaaccgca gatggcgtct ataaggcaac ctataccgcc tataccagag
     1981 gcagtgggct tactgcgaag ctgttaatgc aaaactggaa tgaagatttg cataccgctg
     2041 gatttatcat cgacgccaac ccgcagtcag caaaaattgc gacattatct gccagcaata
     2101 atggtgtgct cgccaatgag aatgcagcaa acaccgtctc ggtcaatgtc gctgatgaag
     2161 gaagcaaccc aatcaatgat cataccgtca cgtttgcggt attaagcggg tcggcaactt
     2221 gctttaacaa tcaaaacacc gcaaaaacgg atgttaatgg tctggcgact tttgatctga
     2281 aaagtagtaa gcaggaagac aacacggttg aagtcaccct tgaaaatggc gtgaaacaaa
     2341 cgttaattgt cagttttgtc ggcgactcga gtaccgcgca ggttgatctg cagaagtcga
     2401 aaaatgaagt ggtcgctgac ggcaatgata gcgccacaat gaccgcgaca gtccgggatg
     2461 caaaaggcaa cctgctcaat gacgtcaagg tcactttcaa tgttaattca gcagcagcga
     2521 aactgagcca aaccgaagtg aatagccacg acgggatcgc cacagctacg ctgaccagtt
     2581 tgaaaaatgg tgattatagg gttacggcct ctgtgagctc tggttctcag gctaatcaac
     2641 aggtgatttt tatcggtgat caaagtactg ctgccctgac cctcagtgtg ccttcaggtg
     2701 atatcaccgt caccaacaca gctccgctac atatgactgc aaccttgcag gataaaaatg
     2761 gcaacccatt aaaagataaa gaaatcacct tctctgtgcc aaacgacgtc gcaagtcggt
     2821 tctcgattag caacagcgga aaaggcatga cggatagcaa cgggactgca atcgcctccc
     2881 tgaccggcac gttagcgggc acgcatatga tcacggctcg tctggctaac agcaatgtca
     2941 gcgatacaca gccaatgacg tttgtggcgg ataaagacag agcggttgtc gttctgcaaa
     3001 catcgaaagc ggaaatcatt gggaatggcg tggatgagac aactctgaca gcaacagtga
     3061 aagatccgtc gaatcatccg gtggcgggga taacggtcaa cttcaccatg ccacaggacg
     3121 ttgcggcaaa ctttaccctt gaaaataacg gtattgccat cactcaggcc aatggggaag
     3181 cgcatgtcac gctgaaaggt aaaaaagcgg gcacgcatac ggttaccgca acgctgggta
     3241 ataacaatac cagtgattcg cagccggtaa catttgtggc ggacaaagcc tcggctcagg
     3301 ttgtcctgca gatatcaaaa gatgagatca caggtaatgg cgtcgatagc gcaacgctaa
     3361 ctgcaacggt taaagatcag ttcgacaatg aggtgaataa tcttccggta acattcagct
     3421 cagcctcttc aggactcacc ctgaccccgg gagtgagtaa taccaatgag tctggcatcg
     3481 cgcaggccac tatcgcaggc gttgcctttg gtgagcagac ggtcacggca tcactggcta
     3541 ataatggtgc cagcgacaac aaaactgtgc attttattgg cgacacagcg gcggcaaaaa
     3601 ttatcgagtt gacgcctgtc ccagacagca taatcgccgg taccccgcag aacagcaccg
     3661 gcagcgtcat caccgccaca gtcgttgata ataatggctt tccggtgaaa ggtgtgactg
     3721 tgaacttcac cagccgaaca aactctgccg aaatgacgaa tggcggccaa gccgtaacga
     3781 acgaacaggg taaggcaacc gtcacttata ccaatacccg ctcctcgata gaatcaggag
     3841 cgagaccgga taccgttgag gccagtctgg aaaatggtaa ctccacgctt agcacatcaa
     3901 ttaatgtcaa cgcggatgcg tctacagcac atctcacctt gctacatgca ctttttgata
     3961 cagtctccgc aggcgagaca accagtctgt atattgaggt gaaggataat tacggcaatg
     4021 gtgtacccca gcatcaggta accctcagcg tttcaccaag tgaaggcgtg accctcagta
     4081 ataacggtat atatactacc aactactacg gctattttta cgcaagcttt accgctacaa
     4141 aagccggggt ttatcaagtg acggcaaccc tcgacaatgg cgattcgatg caacaaacag
     4201 tgacctatgt gccgaacgtc gcgaatgctg aaatcacgct ggcagcctcg aaggatccgg
     4261 tgattgccga caataacgat ctcacaacac taacagcaac agtcgctgat acagagggca
     4321 atgcgatagc caacactgag gtaacattta ctctgccgga agatgtgagg gcgaacttca
     4381 cgctgagcga tggcggtaaa gcgattactg atactgaagg caaagcgaaa gtcacgctga
     4441 aaggtataaa agcaggcgct catactgtta cagcatcgat ggctggcagt aagagtggac
     4501 aactggtggt gaactttact gcggatacgc tcactgcgca ggttaatctt aacgttaccg
     4561 aggacaattt catcgccaat aacattggga tgaccaagct gcaggcaaca gtgactgatg
     4621 gaaacggcaa cccattcgcc aatgaggcgg tgacattcac gctaccggca gatgtgagcg
     4681 caagcttcac tctcggacaa ggcggttccg ccattactga tatcaacggc aaggctgaag
     4741 ttacactgag cggtaccaaa tccggcacct atcccgtgac agttagcgtg atcaattatg
     4801 gtgtcagtga tacgaaacag gtgactttga ttgccgatgc tggtaccgca acactagcct
     4861 ccttaacctc tgtatactca ttcgtcgtta gcacgaccga gggcgcgacc atgactgcaa
     4921 gcgtcactga cgctaacggc aacccggtag aaggcataaa agttaatttc cgcggaacct
     4981 ccgtcacgct aagcagcacc agcgttgaaa cggatgatca gggtttcgct gaaattcttg
     5041 tgacaagcac cgaagtcgga ctgaaaacag tttcagcctc tctggcagat aaacctactg
     5101 aagtcatatc gcgattactg aatgcaaaag cagatattaa ttctgcaacg attaccagtc
     5161 tggagatacc tgaaggtcag ctaatggtcg cacaagacgt agcagttaaa gctcacgtca
     5221 acgaccagtt tggcaacccg attcttaatg aatctgtaac attcagtgca gagccaccag
     5281 agcacatgac catcagccaa aatattgtct ctactgatac gcatggtata gccgaggtct
     5341 ccatgacgcc cgaaagaaac ggttcgtata tggtgaaagc atccctggcg aatggagcct
     5401 cacttgagaa acaactggag gctattgatg aaaaactgac actcacggcg tccagtccgc
     5461 ttatcggtgt ctatgcccct acaggcacta ctctgacggc aacgctaacc tctgcaaatg
     5521 gcactccagt ggagggtcag gtcatcaact ttagcgtaac gccagaaggg gcgacgttaa
     5581 gtggcggaaa agtgagaact aactcttcag gtcaggctcc ggtcgttctg accagcaata
     5641 aagtcggtac atatacggtg actgcatcgt tccataacgg cgtaacaata cagacacaga
     5701 caaccgtgaa agtcactggc aactcaagca ccgcacatgt tgctagcttt atcgctgatc
     5761 catcgactat cgccgccacc aacagtgatt taagtacctt aaaggcaacg gttgaggatg
     5821 gcagtggtaa cctgatcgaa ggtctcactg tgtacttcgc cttaaaaagc ggctctgcca
     5881 cattaacgtc attaacagcg gtgaccgatc aaaacggaat cgcgacaaca agcgtgaaag
     5941 gagcgatgac aggtagcgtc acggtaagcg cagtcacgac cgctggtgga atgcaaacag
     6001 tagatataac gctggtggca ggcccggcag acgcctcgca gtccgtcctt aagaacaatc
     6061 ggtcctcact gaaaggggac tttaccgata gtgctgagct acatcttgtt ttgcacgata
     6121 tatcaggcaa tccgatcaaa gtttctgaag ggatggaatt tgtgcaatca ggtactaacg
     6181 tgccctatat gaaaattagc gcaattgatt acagtcaaaa tatcaacggt gattacaaag
     6241 ccaccattac aggcggcgga gagggtatcg caacgctgat ccctgtattg aatggtgttc
     6301 atcaagctgg tctgagtacc acaatacaat tcactcgcgc agaagacaaa ataatgagcg
     6361 gtacagtatc agtcaatggt actgacctac cgacaactac attcccttcg caggggttca
     6421 ccggggcgta ttatcagttg aataatgaca actttgcccc aggaaaaacg gcggctgatt
     6481 atgagttttc aagctctgcc tcctgggtcg atgttgatgc taccggtaaa gtgacattta
     6541 aaaatgtcgg cagcaattgg gaaaggatta cggcgacgcc aaaatcagga ggccctagct
     6601 atgtatacga aatccgtgtg aagagttggt gggtgaactc cggcgatgct ttcatgatat
     6661 acagccttgc tgaaaatttt tgcagtagca atggctacac acttccccgt gcagatcatt
     6721 taaaccatag tcgttcccga ggcatcgggt cactgtacag tgaatgggga gatatggggc
     6781 attacacgac tgaagctggt tttcaatcaa atatgtattg gtcatctagt cccgcaaact
     6841 caagcgaaca atacgtagtt tccctggcaa caggtgatca aagcgtattt gaaaagcttg
     6901 ggtttgctta tgcgacatgt tataaaaacc tgtgattttc cgttataatt tcttaaagag
     6961 tgctccattc ggagcactct tttttacatt ccctctatag agcttgccct tctctcacag
     7021 aaaatgaata aataaaactg ctgcaccgca agaatcgcgt tcgatgtgac tatgatcgta
     7081 tccggtgagt acagctttga tccaaaggct ggttttctgt gatgattgac cagcctcaga
     7141 gtattgatga caccaccgtt cataacagat cggcattact atgcataagt actgtctcat
     7201 attctcgcca aaacactttt taatgccttt gcgaattcat ccagacttat attgtcaatt
     7261 ttttgcccaa cgacgactga ctccgaaaca tcggccattg cgggccatcg cgttttgtaa
     7321 tcagcataaa ttgcaacaac gggagtatta taggcacttg ccatatgtaa tattgaggtg
     7381 tcaggagtta ttgcgatata agcatctttt atgattgctg ctgaacgttt aatcgagggt
     7441 gataaggata aacggtagac attattataa caatccacta ataccctggc tttatcttcc
     7501 ccttttggtc catgaacgat cactattggt atatctgttt cactttgaat ttttgctatt
     7561 agattttctg caatcgataa tgaaaatgta cgttcctgcg agctaccttc taaattaagc
     7621 gcaatgtaag atcctaacga tcgcatttcc tcgcgcacct catcgagtac atcctcactt
     7681 agtggcaatt catatattgg cctgactgct ggaaaacccg cctcacgcat cataaatgcc
     7741 catgtcatgg gtacaggagc ccggagattc tgatccatcc gggacgcgtt cttgcacaaa
     7801 ggggagtagc acttcatggt taaaccaaca acctgaaaat tcgtttttgc tttcaactga
     7861 ctgataaata tcatcgtttt caggttcttt ttacgcatcg cctctataca aagatccggc
     7921 gtaccgtatt tctgtgttat gttctttgct aaatctttta tttcttttaa tgttgcgtga
     7981 tcctgcatag tcattgtgac taatgttaat ttagtctttt caagtttaag tgcattaaac
     8041 acttctaaat taattgtcga cgtaacaatt aaaagatgct taattttatg caattcaagc
     8101 gcccgaataa caggaaagat ggccatagca tcgccaatct ggtcgggaat atggatgaca
     8161 acaaagtctg ttttttcaat attgaaatta taagctttat aatcgtagta actaaatgca
     8221 atacgtctca acaatgatgc taaaaacata cctaacctcg cctccctact ggttataatg
     8281 caatgcagtc tatcagactc atcagggtgc cattttgtgc atatgcggac ttttatgttt
     8341 catatctcta acctgtggct cctctgctta atccttaaac aacaccagca actcctgcgc
     8401 tttcatcttc catcgaattt ttcatgttgc cgctaatcag ccataaaatc atttgcagat
     8461 gcgctctgtc gaggtagtct cataaggttc gtttatagat cgacggcaat gtgagttacc
     8521 ttttccatac taattataaa aagacagtac aaacaggatc attatggact ccacgctcat
     8581 ctccactcgt cccgatgaag ggacgctttc gttaagtcgc gcccgacgag ctgcgttagg
     8641 cagcttcgct ggtgccgtcg tcgactggta tgatttttta ctctatggca tcaccgccgc
     8701 actggtgttt aatcgcgagt ttttcccgca agtaagcccg gcgatgggaa cgctcgccgc
     8761 atttgctacc tttggcgtcg gattcctttt ccgtccgctc ggcggtgtca ttttcggtca
     8821 ctttggcgac cgactgggac gtaagcgcat gttaatgctg accgtctgga tgatgggcat
     8881 cgcgacagcc ttgattggta ttcttccttc attctcgacc attgggtggt gggcacctat
     8941 tttactggtg acgctgcgtg ccattcaggg atttgccgtc ggcggcgaat ggggaggcgc
     9001 ggcgttgctt tccgttgaaa gtgcaccaaa aaataaaaaa gccttttaca gtagcggtgt
     9061 acaagttggc tacggtgtag gtttactgct ttcaaccgga ctggtttcat tgatcagtat
     9121 gatgacgact gacgaacagt ttttaagctg gggctggcgc attcctttcc tgtttagcat
     9181 cgtactggta ctgggagcat tgtgggtgcg caatggcatg gaggagtccg cggaatttga
     9241 acaacagcaa cattatcaag ctgccgcgaa aaaacgcatc ccggttatcg aagcgctgtt
     9301 acgacatccc ggtgctttcc tgaagattat tgcgctacga ctgtgcgaat tgctgacgat
     9361 gtacatcgtt actgcctttg cacttaatta ttcaacccag aatatggggt taccgcgcga
     9421 acttttcctc aatattggtt tgctggtagg tggattaagc tgcttgacaa ttccctgttt
     9481 tgcctggctt gccgatcgtt ttggtcgccg cagggtttat atcacaggtg cgttaatcgg
     9541 aacgttgagc gcatttcctt tctttatggc gcttgaagca caatctattt tctggatagt
     9601 tttcttctcc ataatgctgg caaacattgc gcatgacatg gtggtgtgtg tgcaacaacc
     9661 gatgtttacc gaaatgtttg gtgccagtta tcgctatagt ggtgctggag tcggttatca
     9721 ggtcgccagt gtggttggcg gtggatttac accttttatt gccgctgcac tcatcactta
     9781 ctttgccggg aactggcata gcgtcgccat ttatttgctg gctggatgtc tgatttccgc
     9841 aatgaccgct ttgttgatga aagacaatca acgcgcttga tagtctggcg aagatcatcc
     9901 gatcttcgcc ttacactttt gtttcacatt cctgtgacat actatcggat gtgcggtaat
     9961 tgtatggaac aggagacaca catgaataat aagggctccg gtctgacccc agctcaggca
    10021 ctggataaac tcgacgcgct gtatgagcaa tctgtagtcg cattacgcaa cgccattggc
    10081 aactatatta caagtggcga attacctgat gaaaacgccc gcaaacaagg tctttttgtc
    10141 tatccatcac tgaccgtaac ctgggacggt agcacaacca atccccccaa aacgcgcgca
    10201 tttggtcgtt ttactcacgc aggcagctac accaccacga ttactcgccc tactctcttt
    10261 cgttcgtatc tcaatgaaca acttacgttg ctgtatcagg attatggtgc gcatatctcg
    10321 gtgcaaccct cgcagcatga aatcccctat ccttatgtca tcgatggctc tgaattgaca
    10381 cttgatcgct caatgagcgc tgggttaact cgctacttcc cgacaacaga actggcgcaa
    10441 attggcgatg aaactgcaga cggcatttat catccaactg aattctcccc gctatcgcat
    10501 tttgatgcgc gccgcgtcga tttttccctc gcgcggttgc gccattatac cggtacgcca
    10561 gttgaacatt ttcagccgtt cgtcttgttt accaactaca cacgttatgt ggatgaattc
    10621 gttcgttggg gatgcagcca gatcctcgat cctgatagtc cctacattgc cctttcttgt
    10681 gctggcggga actggatcac cgccgaaacc gaagcgccag aagaagccat ttccgacctt
    10741 gcatggaaaa aacatcagat gccagcatgg catttaatta ccgccgatgg tcagggtatt
    10801 actctggtga atattggcgt gggaccgtca aatgctaaaa ccatctgcga tcatctggca
    10861 gtgctacgcc cggatgtctg gttgatgatt ggtcactgtg gcggattacg tgaaagtcag
    10921 gccattggcg attatgtact tgcacacgct tatttacgcg atgaccacgt tcttgatgcg
    10981 gttctgccgc ccgatattcc tattccgagc attgctgaag tgcaacgtgc gctttatgac
    11041 gccaccaagc tggtgagcgg caggcccggt gaggaagtca aacagcggct acgtactggt
    11101 actgtggtaa ccacagatga caggaactgg gaattacgtt actcagcttc tgcacttcgt
    11161 tttaacttaa gccgggccgt agcaattgat atggaaagtg caaccattgc cgcgcaagga
    11221 tatcgtttcc gcgtgccata cgggacacta ctgtgtgttt cagataaacc gttgcatggc
    11281 gagattaaac ttcccggcca ggctaaccgt ttttatgaag gcgctatttc cgaacatctg
    11341 caaattggca ttcgggcgat cgatttgctg cgcgcagaag gcgaccgact gcattcgcgt
    11401 aaattacgaa cctttaatga gccgccgttc cgataataag ttctgaacct tcttatcaga
    11461 aatagatgtg aaggagtaag taagacacct ggcaaatagc ctgcaataat cgtgggctgt
    11521 ttgcttcctt gggcggatac gtgttttatt atcgtcttaa tgatttccac atattaaaag
    11581 caag
//
LOCUS       DAZUDJ010000114        11299 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.115, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000114 DAZUDJ010000000
VERSION     DAZUDJ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11299
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.115"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..387
                     /locus_tag="ACHY1N_004555"
     CDS             <1..387
                     /locus_tag="ACHY1N_004555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046735.1"
                     /translation="RLSPHRLIKVLELFNASQSKALPFAEHSKYIYVMHKNQRKYLSI
                     FEGDKTLPVVDYMVVLNHGTTVDGEEKNIISAVFLSNMDGNVQNVPVRLKLKSQLRTG
                     YAERYQAIASQYSSRIGVDYVSMMLP"
     gene            complement(459..875)
                     /locus_tag="ACHY1N_004556"
     CDS             complement(459..875)
                     /locus_tag="ACHY1N_004556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046736.1"
                     /translation="METLFKVFEKFSSRPLFFIFFGLSLCEFFQKQSVLMNPSADNIA
                     KLFAAMILVVFFTWGFEWLIFKFNVNLEPHDQGDIGPTIGTATLAVYLVYAFHFLSEN
                     PEALNLKLLTNSGFIYSTTLLLFSLECMKLRRLKQK"
     gene            complement(914..2143)
                     /locus_tag="ACHY1N_004557"
     CDS             complement(914..2143)
                     /locus_tag="ACHY1N_004557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase domain-containing protein"
                     /protein_id="HFS4046737.1"
                     /translation="MAKIAKKLTDTEIKSTKPADKEINLFDSDGLILRIAPLAKGGKK
                     NWYFRYAVPVSKKRTKMSLGTYPHLTLARARALRDEYLSFLANGVDPQIHNNDKAKAL
                     KSATEHTLQAVARKWLDEKVKTSGISQDHAADIWRSLERNVFPGLGNVPINEIRPKLL
                     KQHLDPIEQRGVLETLRRIISRLNEIFRWAATEELIEFNPADNLGQRFSKPKKQNMPA
                     LPPSELPRFMESLTNASIRLETRMLIEWQLLTWVRPGEAVRARWSDIDTTNSIWNIPA
                     DFMKMKKLHKVPLSKEALRILELMKSISGHREWVFPSIKAPLNHMHEQTANAAIIRMG
                     FGGELVAHGMRSIARTAAEESGKFRAEVLEAALAHSKKDEIIAAYNRAEYLIERQSLM
                     QWWSDYVQAQRSNALVA"
     gene            complement(2431..3096)
                     /locus_tag="ACHY1N_004558"
     CDS             complement(2431..3096)
                     /locus_tag="ACHY1N_004558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046738.1"
                     /translation="MLQRDPHGFRKDVKEFITMIKSFQVDIRTENNLTSAYKHVLFLE
                     FIHNSHPEISHKTFIKSIIYDVLSSITAILHKRERYLHLNFRSMIEHLARISLQKVDN
                     GGDFDITIRTLDFENLKSTNTDENWAYMHSQYKQACGWLHSSSKVKLNITASFPDLLK
                     SDSKSNAAKLSTHLQKMTTEMLKIFFNYYVDEIQTSFYRTRGEMRYVLGNHNFEYFLS
                     KNP"
     gene            complement(3096..3509)
                     /locus_tag="ACHY1N_004559"
     CDS             complement(3096..3509)
                     /locus_tag="ACHY1N_004559"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046739.1"
                     /translation="MNKNSNNLELLQTLVYKKPSSKEAFIGLITIAIYSREIFVKNED
                     AAEFVKNVFGLSFLDYVIKSRTLLCARLTRNLVNMSERDIKECIYKASEYFKTDKFII
                     GYNENSLTFKKSNVKRNANRDVGTWINALLKKDRK"
     gene            complement(3502..4353)
                     /locus_tag="ACHY1N_004560"
     CDS             complement(3502..4353)
                     /locus_tag="ACHY1N_004560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000211299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4046740.1"
                     /translation="MTTPVISFINMKGGVGKTTLCVGIAEYLANFMDKKVLIIDIDPQ
                     FNATQSILSKYDRVKEYIADHLENTKTIRRIFETKSSLTGKVQQVTPDEIIIKMSEHL
                     DMIFGDINTIFDIEQPAARLHKLKRFIEEHKLRDIYDFILIDSPPTISLFTDAALVAS
                     DYYIVPVKIDHYSILGATSLLSVIENIQDNYDHKNIQNLGFIYTNTLENLSKKTKKLK
                     TDFESTEPFNELYFFDNQLKFVQDLMVGGRGNISSSYKSSRKYIKAICEEFLSRIQEV
                     QTGGEDE"
     gene            complement(4604..5779)
                     /locus_tag="ACHY1N_004561"
     CDS             complement(4604..5779)
                     /locus_tag="ACHY1N_004561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3596 domain-containing protein"
                     /protein_id="HFS4046741.1"
                     /translation="MGQTKLLKLPRGVTIRKHRQGETINITFTYKGVRCREPLSNLEV
                     TPKNIKYAERTLGEIHNKIERGTFIYAEYFPRSARLKIFGNAAAGKTVKMYLDEYLEI
                     CETRKLSPSTIGGYKKCRSALASLHICPASELTPATLKAWIQSQKTTLKTIRNQLSFL
                     RSALDEAVTDGVLQINPVSLVTASRYQSDKSEAESSYVVDPLSPAEVDALLAAAGNKQ
                     WENLFRFAIHTGLRSSELCALRWRDIDFVGKTAHVQSASVVGVIKGTKTKAGTRKVEL
                     TEEAMLALINQKPFTFMKDATVFEDPKTNKPWASADAIRKKAWVPTLRKAGIRYRNPY
                     QTRHTYATKYISQGANLFWLAGQMGHKGPEMLFRHYGRYLSDYDNHSSTTLTSNCKK"
     gene            complement(5740..5946)
                     /locus_tag="ACHY1N_004562"
     CDS             complement(5740..5946)
                     /locus_tag="ACHY1N_004562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001440432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFS4046742.1"
                     /translation="MLNLDCVPISTYCKETGETPEAINKRVQRGVWREGVQVLKVEGV
                     KERWIDLSEVAKWARQNCSNYRAA"
     gene            complement(6006..6221)
                     /locus_tag="ACHY1N_004563"
     CDS             complement(6006..6221)
                     /locus_tag="ACHY1N_004563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001331173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046743.1"
                     /translation="MSVIKTHTGIVITRDGEKRMKLHSTETSWVAGRCESYDKKTGYR
                     WGAPNMRRRLLLDSIRPIKQVATREQN"
     gene            complement(6218..6580)
                     /locus_tag="ACHY1N_004564"
     CDS             complement(6218..6580)
                     /locus_tag="ACHY1N_004564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046744.1"
                     /translation="MRMNVFEMEGFLRGRCVPRDLKVNETNAEYLVRKFDALEAKCAA
                     LESKIIPVSAELPPANESVLLFDANGEGWLIGWRSLWYTWGQKETGEWQWTFQVGDLE
                     NVNITHWAVMPKAPETKK"
     gene            complement(6571..7107)
                     /gene="yfdR"
                     /locus_tag="ACHY1N_004565"
     CDS             complement(6571..7107)
                     /gene="yfdR"
                     /locus_tag="ACHY1N_004565"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HFS4046745.1"
                     /translation="MSFIKTFSGKHFYYDRINKDNIDINDIAVSLSNICRFAGHLSHF
                     YSVAQHAVLCSQLVPQEFAFEALMHDATEAYCQDIPAPLKRLLPDYKRMEEKIDAVIR
                     EKYGLPPVMSTPVKYADLIMLATERRDLGLDDGSFWPVLEGIPATEMFNVIPLAPGHA
                     YGMFMERFNELSELRKCA"
     gene            complement(7236..8060)
                     /locus_tag="ACHY1N_004566"
     CDS             complement(7236..8060)
                     /locus_tag="ACHY1N_004566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdQ family protein"
                     /protein_id="HFS4046746.1"
                     /translation="MSQNLDATAINQIHALISAQGVNEIISKIGADAVALPENFRIHD
                     LEKFNLNRFRFRGALSTASIDDFTRYSKDLADEGTRCFIDADNMRAVSVLNLGTIDEP
                     GHADNTATLKLKKAAPFSALLSVNGERNSQKSLAEWIEDWADYLVGFDANGDTIQATK
                     AAAAVRKITIEANQTADFEDNDFSGKRSLMESVEAKTKDIMPVAFEFKCVPFEGLKER
                     PFKLRLSIITGDRPVLVLRIIQLEAVQEDMANEFRDLLVEKFKDSKVETFIGTFTA"
     gene            complement(8125..8487)
                     /gene="yfdP"
                     /locus_tag="ACHY1N_004567"
     CDS             complement(8125..8487)
                     /gene="yfdP"
                     /locus_tag="ACHY1N_004567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416860.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YfdP"
                     /protein_id="HFS4046747.1"
                     /translation="MASERSTDVQAFIGELDGGVFETKIGAVLSEVASGVMNTKTKGK
                     VSLNLEIEPFDENRVKIKHKLSYVRPTNRGKISEEDTTETPMYVNRGGRLTILQEDQG
                     QLLTLAGEPDGKLRAAGH"
     gene            complement(8502..8812)
                     /locus_tag="ACHY1N_004568"
                     /pseudo
     CDS             complement(8502..8812)
                     /locus_tag="ACHY1N_004568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9088..9363)
                     /locus_tag="ACHY1N_004569"
     CDS             complement(9088..9363)
                     /locus_tag="ACHY1N_004569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046748.1"
                     /translation="MKVQILNNNCEVVWSYDIAAPVDQSGDSWTNGKHQIMAGVVFSL
                     RRALEQAEVFPSDPEWKWPFSICPNSESTFQKIGQKVALEEHQPTVS"
     gene            complement(9570..10196)
                     /locus_tag="ACHY1N_004570"
     CDS             complement(9570..10196)
                     /locus_tag="ACHY1N_004570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family protein"
                     /protein_id="HFS4046749.1"
                     /translation="METVGQRIKALRRVTGTSQKELGKFCGVSDVAVGYWEKDINTPG
                     GEALSKLAKFFNTSIDYILYGAEFEGKLVTNMRRVPVISWVQAGQFTECRAAEVFSEV
                     DKWVDTSLKIGDNSFALEVKGDSMTNPNGLPTIPEGATVIVDPDAEPRHGKIVIARLD
                     GTNEATVKKLVIDGPQKFLVPLNPRYPNIPINGNCLIIGVVKGVQYEL"
     gene            10294..10494
                     /locus_tag="ACHY1N_004571"
     CDS             10294..10494
                     /locus_tag="ACHY1N_004571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/CI family transcriptional regulator"
                     /protein_id="HFS4046750.1"
                     /translation="MTTDDIESYFGSIEKVAAFFGITTEAVYQWRNRPGQLIPKGRAA
                     EAAYRTCGRLPFKPELYEKSNG"
     gene            10532..11083
                     /gene="ymfL"
                     /locus_tag="ACHY1N_004572"
     CDS             10532..11083
                     /gene="ymfL"
                     /locus_tag="ACHY1N_004572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmfL"
                     /protein_id="HFS4046751.1"
                     /translation="MGKHHWKVEKQPEWYVKAVRKTIAALPGGYAEAADWLDVTENAL
                     FNRLRADGDQIFPLGWAMILQRAGGTHFIADAVAQSANGVFVSLPDVEDVDNADINQR
                     LLEVIEQIGSYSRQIRSAIEDGVVEPHEKTAINDELYLSISKLQEHAALVYKIFCISE
                     SNDARECAAPGAVACRDCGETNA"
     gene            11080..>11299
                     /gene="ymfM"
                     /locus_tag="ACHY1N_004573"
     CDS             11080..>11299
                     /gene="ymfM"
                     /locus_tag="ACHY1N_004573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor YmfM"
                     /protein_id="HFS4046752.1"
                     /translation="MNSLTTHYRRSQLIALPVPGGKAKVEYCYAVNVPGDREIVTHSF
                     AEWAVGDFNRQKETVLCDKLTAGSKITTE"
BASE COUNT         3031 a         2407 c         2347 g         3514 t
ORIGIN      
        1 agattaagtc cgcacaggct cattaaagtt ctggagcttt ttaacgccag tcagagtaaa
       61 gcattgccat ttgctgaaca ttcgaaatat atatatgtaa tgcataaaaa tcaaagaaaa
      121 tatctctcta ttttcgaagg ggataaaacg cttcctgttg ttgattatat ggtggtgttg
      181 aatcatggaa caacagttga tggcgaagaa aaaaatatta tttctgccgt gtttttaagt
      241 aatatggatg gcaacgtgca aaatgttcct gtccgactca aacttaaatc tcaactgaga
      301 actggttatg cagaaagata tcaggctata gcgtctcagt atagctcaag gattggtgtg
      361 gattatgtat caatgatgct accataatta ttatatttta ggcgtggtga ttttttttcg
      421 ccatgcctat tttatattta tcatcacaat gatgttgttt atttttgttt aagtcttcta
      481 agcttcatgc attctaatga gaataataat agagttgtgc tgtatataaa gccagagtta
      541 gttaataact ttaaatttaa tgcttcagga ttttcactga gaaagtgaaa ggcataaact
      601 aagtatacag ctaaagtagc cgttccaatt gttggtccaa tatcgccttg atcatgaggt
      661 tcaaggttta cattgaactt gaagattagc cattcaaatc cccaagtaaa aaaaacaact
      721 aatatcatgg ctgcgaataa tttcgcgatg ttatctgctg atggattcat cagaacagat
      781 tgtttctgaa aaaattcaca aagtgagagt ccgaaaaaaa taaaaaaaag tggtctggaa
      841 ctaaattttt caaaaacttt gaatagggtt tccattttct ttaccttcag gattatatta
      901 gctattctga tacttaggct accagagcat ttgatctttg agcttgaacg taatcactcc
      961 accattgcat caaactctgt cgctctatca gatattctgc acgattgtat gctgcgataa
     1021 tttcatcttt tttcgagtgg gcaagcgctg cctcaagaac ttcagctctg aatttaccag
     1081 actcctctgc cgctgttcgt gcaatagaac gcataccgtg agctacaagc tcgcctccga
     1141 accccattcg gatgatagct gcgttggctg tttgttcatg catatgatta agaggcgctt
     1201 ttatgctggg gaaaacccat tctctatgcc cacttattga tttcattaat tcaaggatgc
     1261 gcaaagcttc tttactcaaa ggaactttgt gaagcttttt cattttcatg aaatcagcag
     1321 gaatgttcca aatgctgttg gttgtatcaa tatcagacca ccttgcgcga acggcttcac
     1381 ccggacgaac ccatgtcaac aattgccatt caattagcat acgtgtttcc aaccggattg
     1441 acgcattcgt caaagattcc ataaaccttg gcaattcgct tgggggaagg gcaggcatat
     1501 tttgcttttt tggtttactg aatctttgac caaggttgtc agccgggttg aactcaataa
     1561 gttcttcagt agctgcccac cggaagattt cattcagacg tgaaatgata cggcgtagag
     1621 tttccaatac gcctcgttgc tcaataggat caaggtgttg ttttaagagc ttaggtcgga
     1681 tctcattgat agggacatta cccagaccgg gaaagacatt tctctctaag ctgcgccaga
     1741 tgtctgctgc atggtcttgt gagatacctg atgtctttac cttctcatct aaccatttcc
     1801 gcgctacggc ttggagagtg tgctcagtag cactctttaa tgccttcgcc ttatcgttgt
     1861 tatggatttg gggatcaaca ccatttgcca gaaaggagag atattcatca cgtaaggctc
     1921 tggctcttgc aagggtaagg tgaggatatg tcccaaggct cattttggtt cttttcttgc
     1981 tcactggtac tgcatacctg aaataccaat ttttcttgcc tcctttcgcc aaaggagcga
     2041 ttcgtagaat cagaccatca ctgtcaaaca agttgatttc tttatcggct ggcttggtgc
     2101 ttttgatttc agtgtcagtg agcttcttag cgatttttgc cattttggga ccctcggttt
     2161 ttggaccctt cttagtgggt cccattcagg gtgccataac tcgtagttct cagcaattct
     2221 cactggacga caatagacgt aaaaaagccc gcagagcttg tgctgtgtgg gcttagtaga
     2281 cttcattgaa cttcaaacaa ctaaaaagtg gtggagctgg cgggagttga accagcgtcc
     2341 atttgttttt aatttattga tttttattgt tttattttat ttctcgcatg cttcgtgtac
     2401 ttcacgtatc ctttttaagg aaatatatat ttatggattc ttgcttaaaa aatattcgaa
     2461 gttatggttg ccaagcacat acctcatttc tccccgtgtg cggtaaaaag aagtttgaat
     2521 ctcatcaaca tagtagttaa aaaaaatctt taacatttcg gtagtcatct tttgcaaatg
     2581 ggttgacagt ttagctgcat tactttttga atcagacttt aataaatctg gaaatgatgc
     2641 tgtgatattt aatttaactt tagatgatga gtgtaaccag ccacatgctt gtttatactg
     2701 tgaatgcatg tacgcccagt tttcatcagt gttggtagat ttaagattct cgaaatcaag
     2761 agttctaatt gtaatatcga aatccccccc gttatcaact ttttgtaagg atatacgtgc
     2821 aagatgttca atcattgagc gaaaattaag atgaagatat cgctctcgtt tatgaagtat
     2881 cgctgtaatt gaacttaaaa catcataaat aatacttttt ataaaggttt tgtgacttat
     2941 ttctggatgt gagttatgga taaactccag aaaaagtaca tgtttataag ccgatgtaag
     3001 attgttttcg gtgcgaatat cgacctgaaa tgattttatc attgtgataa attctttcac
     3061 gtcttttcta aatccatgtg ggtctctttg aagcattatt ttctatcctt cttcaaaaga
     3121 gcattaatcc acgtacctac atctcgattt gcattacgtt tgacgttact ttttttaaaa
     3181 gtaagtgagt tttcattata tccaataata aatttgtcag ttttaaaata ctctgatgct
     3241 ttatatatgc attctttaat gtctctctcg ctcatattta caagattacg ggtaagtcta
     3301 gcgcataata aagttcttga cttgatgacg tagtctaaga aacttaatcc aaatacattt
     3361 tttacgaatt ctgctgcatc ttcattttta acaaaaattt ccctagaata gattgctatt
     3421 gttatcaaac caataaacgc ttcttttgac gagggcttct tataaaccaa tgtctgtaat
     3481 aattcgaggt tgttactatt tttattcatc ttcccccccc gtttgcactt cttggatccg
     3541 acttaaaaac tcttcacaaa tcgctttgat atattttctg gatgatttat aacttgatga
     3601 tatattacct ctaccaccca ccatcaaatc ctgtacaaac ttcaactggt tatcaaaaaa
     3661 gtatagttca ttaaaaggtt cagtactttc aaagtctgtc tttagctttt ttgtcttttt
     3721 tgatagattt tctagggtat tagtataaat aaaaccaagg ttttgaatgt ttttatggtc
     3781 ataattatct tgaatgtttt ctattacgct taaaagactt gtcgcaccta aaattgagta
     3841 gtggtcaatt ttaactggca caatataata atctgaagca acgagagctg catcagtaaa
     3901 taatgaaatg gttggtgggc tatcgatcaa aatgaagtca tatatatctc gaagcttatg
     3961 ttcttctata aagcgtttta gcttatgtaa tcttgccgca ggttgttcaa tatcaaatat
     4021 tgtattaata tcaccaaaaa tcatatctaa gtgctctgac atcttgatga taatttcatc
     4081 aggagtgacc tgctgaactt tacccgttaa gcttgatttt gtctcgaata ttcgtctgat
     4141 ggtttttgta ttttctaagt gatcagctat atactctttc actcgatcat atttactaag
     4201 tattgactgt gtagcgttaa attgtgggtc aatatcgata attaatacct ttttatccat
     4261 gaagtttgca agatattcag caatgccgac gcataaagtt gttttaccaa ccccaccttt
     4321 catatttatg aaacttatta ctggtgtagt cattttatcc ctctaattta tacttcttaa
     4381 acaaaaattt aaatgttaca tgtaagtgaa tttacttata acattttttt tgaaacaata
     4441 atactgttgt tttatcaggg ggatggcatt tttcaatgga ataaatctat aaggggtatg
     4501 ctcataattg taaagaatac ctattcaagc gtggatttgt ggaggacctc tcgttttgaa
     4561 cgaaataggc ttctttgaat aacatgcttt accttgctca aggctacttt ttgcaattac
     4621 ttgtgagcgt tgttgagctg tggttgtcat aatcactcaa gtaacgccca taatgacgaa
     4681 acaacatttc gggcccctta tgccccatct gccctgctag ccagaagaga ttagctcctt
     4741 ggctaatgta cttagtagca taagtgtgcc tggtctgata tgggtttctg tagcgaatac
     4801 ctgcttttcg caatgttggc acccatgctt ttttcctgat tgcatcagca cttgcccaag
     4861 gcttattggt ctttggatct tcaaagaccg tagcatcttt catgaacgta aatggcttct
     4921 gatttatcag cgccaacatt gcctcttctg tcagttcaac tttacgagta ccggcttttg
     4981 ttttggtccc tttgataaca ccaacaacac ttgcgctctg gacatgtgct gtttttccaa
     5041 caaagtcgat atcacgccat cgaagggcac atagttcaga actacgcagg cctgtatgta
     5101 tagcgaaccg gaacagattt tcccattgtt tgtttccggc tgctgctagt aatgcatcaa
     5161 cttctgctgg tgatagcgga tcaaccacat agctgctttc tgcttctgac ttatcacttt
     5221 ggtagcgcga agctgttact aacgatacgg ggttaatttg aagtacccca tcggtcacgg
     5281 cttcatcaag tgctgaccgc aggaaagata actggttgcg aatggttttt aaggttgttt
     5341 tctggctttg aatccacgct ttcagggttg ctggtgttaa ttcacttgca gggcaaatgt
     5401 gaagtgaggc taacgcacta cggcattttt tatagccacc aatcgtagag ggtgaaagtt
     5461 ttcttgtttc gcagatttca agatattcgt ccaggtacat ctttaccgtt ttgcctgcag
     5521 cagcattacc aaaaattttc aaacgagcag aacggggaaa atattctgca taaatgaatg
     5581 ttcccctttc gatcttatta tggatttcgc cgagtgtacg ctcggcgtat ttaatgttct
     5641 ttggtgttac ttccagattg gaaagcggct cacgacatct aactcctttg taggtgaaag
     5701 ttatattgat cgtttcgccc tggcggtgtt tcctgattgt tacgccgcgc ggtagtttga
     5761 gcagttttgt ctggcccatt ttgcaacctc actaagatca atccacctct ccttaacgcc
     5821 ttcaaccttt aaaacctgaa caccttcacg ccaaacaccg cgctgtacac gtttgtttat
     5881 tgcttcagga gtttcgccag tttctttgca ataagttgag ataggaacac aatcgaggtt
     5941 cagcatatgt ttctccactt agcccgctgc acatgggcag taatatcaaa ttccagtcct
     6001 gataattaat tttgttctct ggttgctact tgttttattg gcctgatgct gtccagtagc
     6061 agacggcgac gcatgttagg tgcaccccaa cggtaaccag tctttttgtc gtaggattca
     6121 caacgtccgg caacccagga cgtttcagtg gaatgtaatt tcatccgctt ttcaccgtct
     6181 cgggtgataa caattcctgt atgagttttt atcacgctca tttcttagtc tctggtgctt
     6241 tcggcattac tgcccagtga gtgatattga cgttttcaag gtccccgacc tgaaatgtcc
     6301 actgccattc tccggtttct ttttgtcccc aggtgtacca gagagaacgc cagccaatca
     6361 gccagccttc tccgttagca tcaaataaca gaacactttc atttgctgga ggcagttcag
     6421 ctgacactgg tattattttg ctttccagtg ccgcacattt agcttcaagc gcgtcgaatt
     6481 tacgtaccag gtactcagca tttgtttcgt tcactttcag atctcgcggt acacatctcc
     6541 cacgaagaaa cccttccatt tcgaaaacat tcatgcgcat ttgcgtaact ccgataactc
     6601 gttaaaacgt tccataaaca tcccgtaggc atggcccggt gccagtggaa tcacgttgaa
     6661 catctctgtt gccgggatgc cttccagtac aggccagaaa gagccatcat caagcccgag
     6721 atcgcggcgt tcggttgcca gcatgatgag atcggcatat ttcacaggcg tgctcataac
     6781 cgggggtaac ccgtatttct cacggattac ggcgtctatt ttttcttcca tccgtttata
     6841 gtcaggaaga aggcgtttca gtggtgcggg gatgtcctgg caatacgctt ctgttgcatc
     6901 atgcattaac gcttcaaaag caaattcctg cggtaccagc tggctgcaaa gcaccgcatg
     6961 ttgggcgacg ctgtagaagt gtgaaagatg gccggcaaag cgacagatat ttgaaaggga
     7021 aaccgcgata tcgttaatat cgatgttgtc tttatttatc ctgtcataat aaaaatgctt
     7081 cccggaaaaa gttttaataa atgacatttt gttctccacg ttatatgcgc tgcaccgcgc
     7141 tgaattttgg ttaaagaaaa ccctcgcctt caggcgatta ttgagtcaat tacgtttcca
     7201 taaatgcccc cgcaggggca tttgcggtaa tgaaatcagg cggtgaaagt cccaataaag
     7261 gtttctactt tgctgtcctt gaatttctca acaagcagat cacgaaattc gttagccata
     7321 tcttcctgca ccgcttccag ctgaataatg cgtagaacca gtaccggacg atcgccagtg
     7381 ataatgctga ggcgtaattt aaacggacgt tctttcagac cttcaaacgg aacgcattta
     7441 aactcaaatg ccactggcat aatgtctttg gtcttcgctt cgacagactc catcagggag
     7501 cgtttgccgc tgaagtcatt atcttcaaaa tcagcagtct ggtttgcttc aatcgtgatt
     7561 ttacggaccg ccgcagccgc ttttgttgcc tgaatggtgt caccattagc atcaaagccc
     7621 acaaggtagt cggcccagtc ttcaatccat tctgccagtg acttctggga gttacgctcg
     7681 ccattaacag acaacagagc agagaacggc gctgcctttt tcagtttgag agtggcggtg
     7741 ttatctgcgt gacctggttc atcaatagta cccaggttaa gcacactgac ggcacgcata
     7801 ttatcagcat cgataaagca gcgggtgcct tcatctgcaa gatctttaga ataacgggta
     7861 aagtcatcga tgctggcagt ggaaagcgca ccacggaaac ggaagcgatt taaattaaat
     7921 ttttccagat catgaatgcg gaaattttca ggtaatgcca ctgcgtcggc accaatctta
     7981 ctgataattt cattaacacc ctgagcagaa ataagggcat ggatttgatt aattgcggtt
     8041 gcgtctaagt tctgagacat aataagtcct cactatataa aatattcagt gatgagataa
     8101 ataatcagtt aattaaaaac gatattaatg acctgctgcg cggagttttc cgtcaggttc
     8161 accggcaaga gtcagtaatt gtccctggtc ttcctgcaga atagtcaggc gaccaccgcg
     8221 attgacatac atcggcgttt cggtggtgtc ttcttcagaa attttcccgc ggttagtcgg
     8281 gcgaacatat gagagtttgt gtttgatttt cacacggttc tcatcaaatg gttcgatttc
     8341 caggttgagt gagaccttac ctttggtttt cgtgttcatc acaccggaag cgacttcact
     8401 gagaactgcg ccgattttgg tttcaaatac gccgccgtcc agctccccga taaatgcctg
     8461 cacatcagta ctgcgttcgc tagccatttt gctgctcctc atcatatcga ccctgcaagg
     8521 ccgattagtt tctccacaaa acagagaaga acacctgcgg tggcagccgc ccggatggat
     8581 tgggttatga gcccgtcgtc cggtgatgct cttctctgtt ttgtaaaaag gacgctacca
     8641 gccggaagca agggtacaaa ctggtaccgc caggactaca cacagcataa agttgtggtg
     8701 ccgggtgcct cccggtgcct ggcgaaggtt gcacaccaga cgggtgggta tccacagaag
     8761 gtcgactgtc agcctcaacc ttaacccgcg tgcgctgagc cgcattcacc acaacgctaa
     8821 ggattctctt tggttgaaaa tacttagctg ttatgtgcct gtcttttcac cacttcaggc
     8881 tcggtggtat ccttttaagc ccgtatacat aaaaggaaaa tcaaatgact tttgatgaaa
     8941 aagaacttga taatgcaatt aataaaatca tcgtaacgtc gctcttttcc tgtctcagcg
     9001 acactcagca gaaacggttc tacgaatcgg ctttcaacat gatcgagcgt tgttgtttct
     9061 gcgatgccga cgagttacct gaaaaaatca ggaaacagtt ggctgatgct cttcgagtgc
     9121 gactttctga ccaattttct gaaatgtgct ctccgaattt ggacaaatag aaaaaggcca
     9181 tttccattca gggtctgatg gaaatacttc agcctgttcc aaagcacggc gtaaagagaa
     9241 cacaactcca gccataatct gatgtttccc attggtccag ctatcgccgc tctgatctac
     9301 aggggcggct atgtcgtatg accaaacgac ttcacagtta ttgtttaaaa tctggacttt
     9361 catttcatac acctgcttta acatgagtgc ctgatggcac aacatgactc aacgaatcat
     9421 cctggacttc atatgcccca ggcggctact tcgtgggcgt cctgcctgtt cgttatcttt
     9481 gatataaaat ctaacttaac ttagttatta tggcaagaga aaacaccaaa cttttcttag
     9541 ttcggtgcct tagttagaga agagaggtct tagagttcgt attgaactcc tttgactaca
     9601 ccaatgataa ggcaattacc attgataggg atgttgggat accgaggatt taatggcact
     9661 aaaaactttt gagggccatc gatgactaat ttttttactg tagcttcgtt tgttccatca
     9721 agtcgagcga tgactatttt tccatgacga ggttctgcat ctggatctac aatcactgtt
     9781 gcgccttctg gtattgttgg gaggccatta gggttagtca tggagtcacc tttaacctct
     9841 aatgcaaatg agttatcacc aatctttaat gatgtatcta cccacttgtc cacttcacta
     9901 aacacttctg ctgccctgca ctcagtaaac tgcccagcct gaacccacga tattacagga
     9961 actctgcgca tgtttgtgac gagtttgcct tcaaactcag caccataaag aatgtaatct
    10021 attgacgtat tgaagaactt cgctaatttc gaaagtgcct ccccaccagg ggtattgatg
    10081 tctttctccc agtaccccac agcaacgtcg cttactccac aaaatttacc caattctttc
    10141 tgggacgttc cggtaactct tctcagagct tttatacgct gaccaaccgt ttccatagga
    10201 gcaccatttc ttgaattgct aagtaatctt agtttttatt gaccaaagat agatttgtaa
    10261 ttagcatcta ataaaactta gtttggaggg cgtatgacaa ctgacgatat cgaaagctac
    10321 ttcggcagta ttgagaaagt tgctgctttt ttcggcataa caactgaagc cgtttatcag
    10381 tggcgaaacc gtccgggcca gttaattcca aaaggacgtg cagcagaagc tgcatataga
    10441 acttgcggac ggttgccatt taaacctgag ctttatgaaa aatctaatgg ataaatcgat
    10501 taacagaaac cacagaacga tgaggctaac cgtgggtaag catcactgga aagtagaaaa
    10561 acagcctgag tggtacgtga aagctgtcag aaaaactatc gcagcgttgc cgggtggtta
    10621 cgctgaagca gctgactggc tggatgtaac agaaaacgca ttatttaacc gccttcgtgc
    10681 cgatggcgat cagattttcc cgctgggatg ggcaatgatt ttgcaacgtg ctggtggaac
    10741 tcacttcatt gctgacgctg tggcgcagtc tgcaaatggc gtctttgtgt ctcttcctga
    10801 cgtcgaggat gtggacaacg ccgatattaa ccagcgcctg ctggaagtca ttgaacagat
    10861 tggcagttat tccagacaga ttcgttcggc aatcgaagac ggtgtggtgg aaccgcatga
    10921 gaagacagca attaacgacg agctgtatct ctcaatttcg aagctgcagg agcatgcagc
    10981 actggtctac aaaatctttt gcatttcaga aagtaatgac gcccgcgagt gtgcagctcc
    11041 gggcgccgtg gcgtgtcgtg actgtggaga aactaacgca tgaacagttt aacaacacac
    11101 taccgtcgct cgcaactgat tgcgcttcct gtaccgggtg gaaaagcgaa ggtggagtat
    11161 tgctatgcag ttaatgtacc aggtgacagg gaaattgtaa cccacagctt tgctgagtgg
    11221 gctgtgggtg atttcaaccg gcagaaggag acagtccttt gcgacaagtt aaccgctggt
    11281 tcaaagatca ctacggagt
//
LOCUS       DAZUDJ010000115        11096 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.116, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000115 DAZUDJ010000000
VERSION     DAZUDJ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11096
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.116"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            193..1335
                     /gene="yghO"
                     /locus_tag="ACHY1N_004574"
     CDS             193..1335
                     /gene="yghO"
                     /locus_tag="ACHY1N_004574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001327865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YghO"
                     /protein_id="HFS4046753.1"
                     /translation="MECDLLMIKIEKVINKNDLKAFIAFPSSLYPDDPNWIPPLFIER
                     NEHLSAKNPGTDHIIWQAWVAKKAGQIVGRITAQIDTLHRERYGEDTGHFGMIDAIDD
                     PQVFAALFGAAEAWLKSQGASKISGPFSLNINQESGLLIEGFDTPPCAMMPHGKPWYA
                     AHIEQLGYHKGIDLLAWWMQRTDLTFSPALKKLMDQVRKKVTIRCINRQRFAEEMQIL
                     REIFNSGWQHNWGFVPFTEHEFATMGDQLKYLVPDDMIYIAEIDSAPCAFIVGLPNIN
                     EAIADLNGSLFPFGWAKLLWRLKVSGVRTARVPLMGVRDEYQFSRIGPVIALLLIEAL
                     RDPFARRKIDALEMSWILETNTGMNNMLERIGVEPYKRYRLYEKQI"
     gene            complement(1342..2106)
                     /gene="glcC"
                     /locus_tag="ACHY1N_004575"
     CDS             complement(1342..2106)
                     /gene="glcC"
                     /locus_tag="ACHY1N_004575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GlcC"
                     /protein_id="HFS4046754.1"
                     /translation="MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFS
                     RSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRA
                     LLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQA
                     SHNQVLVFTLQSLTNLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQ
                     RAARDHVRTVKKNLHDIELEGHHLIRSAVPLEMNLS"
     gene            2357..3856
                     /gene="glcD"
                     /locus_tag="ACHY1N_004576"
     CDS             2357..3856
                     /gene="glcD"
                     /locus_tag="ACHY1N_004576"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009339 - glycolate oxidase complex
                     [Evidence IEA];
                     GO_function: GO:0003973 - (S)-2-hydroxy-acid oxidase
                     activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcD"
                     /protein_id="HFS4046755.1"
                     /translation="MSILYEERLDGALPDVDRTSVLMALREHVPGLEILHTDEEIIPY
                     ECDGLSAYRTRPLLVVLPKQMEQVTAILAVCHRLRVPVVTRGAGTGLSGGALPLEKGV
                     LLVMARFKEILDINPVGRRARVQPGVRNLAISQAVAPHNLYYAPDPSSQIACSIGGNV
                     AENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALDSPGFDLLALFTGSEGMLG
                     VTTEVTVKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGIIPGGLEMMDNLSIRAAE
                     DFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATDVRLAQDEAERVRFW
                     AGRKNAFPAVGRISPDYYCMDGTIPRRALPGVLEGIARLSQQYDLRVANVFHAGDGNM
                     HPLILFDANEPGEFARAEELGGKILELCVEVGGSISGEHGIGREKINQMCAQFNSDEI
                     TTFHAVKAAFDPDGLLNPGKNIPTLHRCAEFGAMHVHHGHLPFPELERF"
     gene            3856..4908
                     /gene="glcE"
                     /locus_tag="ACHY1N_004577"
     CDS             3856..4908
                     /gene="glcE"
                     /locus_tag="ACHY1N_004577"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcE"
                     /protein_id="HFS4046756.1"
                     /translation="MLRECDYSQALLEQVNQAISDKTPLVIQGSNSKAFLGRPVTGQT
                     LDVRCHRGIVNYDPTELVITARAGTPLVAIEAALESAGQMLPCEPPHYGEEATWGGMV
                     ACGLAGPRRPWSGSVRDFVLGTRIITGAGKHLRFGGEVMKNVAGYDLSRLMAGSYGCL
                     GVLTEISMKVLPRPRASLSLRREISLQEAMNEIAQWQLQPLPISGLCYFDNALWIRLE
                     GGEGSVKAARELLGGEEVAGQFWQQLREQQLPFFSLPGTLWRISLPSDAPMMDLPGEL
                     LIDWGGALRWLKSTAEDNQIHRIARNAGGHATRFSAGDGGFAPLSAPLFRYHQQLKQQ
                     LDPCGVFNPGRMYAEL"
     gene            4919..6142
                     /gene="glcF"
                     /locus_tag="ACHY1N_004578"
     CDS             4919..6142
                     /gene="glcF"
                     /locus_tag="ACHY1N_004578"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcF"
                     /protein_id="HFS4046757.1"
                     /translation="MQTQLTEEMRQNARALEADSILRACVHCGFCTATCPTYQLLGDE
                     LDGPRGRIYLIKQVLEGNEVTLKTQEHLDRCLTCRNCETTCPSGVRYHNLLDIGRDIV
                     EQKVKRPLPERILREGLRQVVPRPAVFRALTQVGLVLRPFLPEQVRAKLPAETVKAKP
                     RPPLRHKRRVLMLEGCAQPTLSPNTNAATARVLDRLGISVMSANEAGCCGAVDYHLNA
                     QEKGLARARNNIDAWWPAIEAGAEAILQTASGCGAFVKEYGQMLKNDALYADKARQVS
                     ELAVDLVELLREEPLEKLAIRGDKKLAFHCPCTLQHAQKLNGEVEKVLLRLGFTLTDV
                     PDSHLCCGSAGTYALTHPDLARQLRDNKMNALESGKPEMIVTANIGCQTHLASAGRTS
                     VRHWIEIVEQALEKE"
     gene            6147..6551
                     /locus_tag="ACHY1N_004579"
     CDS             6147..6551
                     /locus_tag="ACHY1N_004579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlcG family protein"
                     /protein_id="HFS4046758.1"
                     /translation="MKTKVILSQQMASAIIAAGQEEAQKNNWSVSIAVADDGGHLLAL
                     SRMDDCAPIAAYISQEKARTAALGRRETKGYEEMVNNGRTAFVTAPLLTSLEGGVPVV
                     VDGQIIGAVGVSGLTGAQDAQVAKAAAAVLAK"
     gene            6573..8744
                     /gene="glcB"
                     /locus_tag="ACHY1N_004580"
     CDS             6573..8744
                     /gene="glcB"
                     /locus_tag="ACHY1N_004580"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004474 - malate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006097 - glyoxylate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase G"
                     /protein_id="HFS4046759.1"
                     /translation="MSQTITQGRLRIDANFKRFVDEEVLPGTGLDAAAFWRNFDEIVH
                     DLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQPERVTVET
                     TGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDP
                     QRGEQVIAWVRRFLDESLPLENGSYQDVVAFKVVDKQLRIQLKNGKETTLRTPAQFVG
                     YRGDAAAPTCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVA
                     AVDAEDKILLYRNLLGLMQGTLQEKMDKNGRQIVRKLNDDRQYTAADGSEISLHGRSL
                     LFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPK
                     MHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFIN
                     TGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGM
                     WAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHAMHYHQTNVQSVQANIAQTEFN
                     AEFEPLLDDLLTIPVAENANWSVEEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIH
                     NVALMEDRATLRISSQHIANWLRHGILTKEQVQASLENMAKVVDQQNADDPAYRPMAG
                     NFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH"
     gene            9099..10781
                     /gene="glcA"
                     /locus_tag="ACHY1N_004581"
     CDS             9099..10781
                     /gene="glcA"
                     /locus_tag="ACHY1N_004581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate permease GlcA"
                     /protein_id="HFS4046760.1"
                     /translation="MVTWTQMYMPMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGA
                     ITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIVAAVFLYKLTVASGQFDI
                     IRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLC
                     LIANTAPVAFGALGVPILVAGQVTGIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWK
                     GVKETWPAALVAGGSFAVTQFFTSNYIGPELPDITSALVSIVSLALFLKVWRPKNTET
                     AISMGQSAGAMVVNKPSSGGPVPSEYSLGQIIRAWSPFLILTVLVTIWTMKPFKALFA
                     PGGAFYSLVINFQIPHLHQQVLKAAPIVAQPTPMDAVFKFDPLSAGGTAIFIAAIISI
                     FILGVGIKKGIGVFAETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMF
                     PFFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMIS
                     PQSIAVACAATGMVGRESELFRYTVKHSLIFASVIGVITLLQAYVFTGMLVS"
BASE COUNT         2592 a         2766 c         3086 g         2652 t
ORIGIN      
        1 gaagaagcct tgtccggtcg ccttaaatcg acaaaaggca ttgaggcgct tctgtgtagt
       61 ctctaacctt atcataatca ttaataaata ctatttattc tttgtttgta ttcattgggt
      121 tgattattaa ggtgtcgttc gttgctgttg caacctgttt ttcaccgtta attatttgtt
      181 atccacagag atatggaatg cgatctgctg atgattaaaa ttgaaaaagt aattaataaa
      241 aatgacctta aggcatttat cgcttttccg tcatcacttt atcccgacga tccaaactgg
      301 ataccccctt tattcataga acgcaacgag catttgtctg cgaaaaatcc ggggacggac
      361 catatcatct ggcaggcgtg ggtggcaaaa aaagcggggc agatagttgg gcgtattacc
      421 gcgcaaatag ataccttgca ccgtgagcgt tacggtgaag ataccggtca tttcggcatg
      481 attgacgcca ttgatgatcc gcaggttttt gccgcgttgt ttggcgcagc ggaagcgtgg
      541 ttgaagtcac aaggtgcaag taagatcagc ggtcctttca gcctgaatat caatcaggaa
      601 agcggattac tgattgaagg ttttgacaca ccaccctgtg cgatgatgcc acacggcaaa
      661 ccgtggtatg ccgcgcatat tgaacaactg ggttatcaca aaggcattga tttactggcg
      721 tggtggatgc agcgaaccga tctcactttc tctccggcgc taaaaaaact gatggatcag
      781 gtgcgcaaaa aggtgaccat tcgctgcatc aatcgtcagc ggtttgccga agaaatgcag
      841 atcctgcgtg agattttcaa ctctggctgg cagcacaact ggggatttgt gccgtttacc
      901 gaacatgaat tcgcgaccat gggcgatcaa cttaaatatc tggtgccgga cgatatgatc
      961 tatatcgctg agattgattc tgcaccctgc gcgtttattg tcggcttgcc gaacatcaac
     1021 gaggcgattg ccgatctgaa cggatcgctc tttcccttcg gctgggcaaa attgctgtgg
     1081 cgtttgaaag tcagcggtgt gcgaactgcg cgagtaccgc tgatgggcgt gcgcgacgag
     1141 tatcagttca gccgcatcgg cccggtgatt gcgctgttat tgattgaagc cttacgcgat
     1201 ccgtttgccc gccggaagat cgatgcgctg gagatgtcat ggatcctcga aaccaataca
     1261 ggcatgaata acatgctgga acgcattggg gtggagccgt acaagcgtta ccgattgtat
     1321 gaaaagcaga tttaatacca gctaactcag gttcatctcc agcggcaccg ccgagcgaat
     1381 caaatggtgg ccttccagct cgatatcgtg gagattcttt ttcacggtcc gcacatgatc
     1441 gcgtgctgcg cgctgggcga cgtgcggcag ccgctgcaac accgcgttgt agatcctcgc
     1501 atgctggcga tcgatctgct ttttttgctg tggtcgatgg tagagattat ttacgctggc
     1561 aaacactgaa ttaaacatca gattggtcaa tgattgcagc gtaaacacca gcacctgatt
     1621 gtgagaagcc tgacaaatgg cgagatggaa agcgtgatcc aactgcgcat gttcgatcag
     1681 cgaaatctct ttgttgttct cactggcggc gagcattttt tcataacagc gggttatcac
     1741 aacaaaatca gcctgcgttc ccagcgttgc cgccagcctt gccgattcgc cctccagtaa
     1801 tgcgcgaacg tcgagcagat cgtacagcgt tcgcggctgc gtactgaaca gatggatcag
     1861 cgggctggtg tcctgcaccc gattaagccg tgcgacacga gaatcgcgac cctgcgccgt
     1921 ttcaataatc ccgcgcccgc gcagcacggt cagcccttca cgcagtgcgg agcgtgagaa
     1981 gccgagcttt tcacacagtc gacgttccga gggaagtggc tgaccgacct tcagtacgcc
     2041 gtcgataatt aaccgttcga tactctctgc aaccacttcg caaatagggc gacgttcatc
     2101 tttcattccc ggacctcgtg cacaggtagg accaattttt ctgttcttaa ctcgcaaaac
     2161 acgcacatca cgtaagtgat tatgttacat caatttaaca ttgagttaac caaggcaagg
     2221 tcacagagct ggaaaaaaaa tggtctgacc ggtagctaaa gagatagacg aaaacgaaaa
     2281 gcccgcttaa taactgttca cagaagcagc gcgcaaaaat cagctgccac acaacacaac
     2341 aaagcgaagc ctactcatga gcatcttgta cgaagagcgt cttgatggcg ctttacccga
     2401 tgtcgaccgc acatcggtac tgatggcact gcgtgagcat gtccctggac ttgagatcct
     2461 gcataccgat gaggagatca ttccttacga gtgtgacggg ttgagcgcgt atcgcacgcg
     2521 tccattactg gttgttctgc ctaagcaaat ggaacaggtg acagcgattc ttgctgtctg
     2581 ccatcgcctg cgtgtaccgg tggtgacccg tggtgcaggc accgggcttt ctggtggcgc
     2641 gctgccgctg gaaaaaggtg tgttgttggt gatggcgcgc tttaaagaga tcctcgacat
     2701 taaccccgtt ggtcgccgcg cgcgcgtgca gccaggcgtg cgtaacctgg cgatctccca
     2761 ggccgttgca ccgcataatc tctactacgc accggaccct tcctcacaaa tcgcctgttc
     2821 cattggcggc aacgtggcag aaaatgccgg cggcgtccac tgcctgaaat atggtctgac
     2881 cgtacataac ctgctgaaaa ttgaagtgca aacgctggac ggcgaggcgc tgacgctggg
     2941 atcggacgcg ctggattcac ctggttttga cctgctggcg ctgttcaccg gatcggaagg
     3001 tatgctcggc gtgaccaccg aagtgacggt aaaactgctg ccgaagccgc ccgtggcgcg
     3061 ggttctgtta gccagctttg actcggtaga aaaagccgga cttgcagttg gtgacatcat
     3121 cgccaatggc attatccccg gcgggctgga gatgatggat aacctgtcga tccgcgcggc
     3181 ggaagatttt attcatgccg gttatcccgt cgacgccgaa gcaattttgt tatgcgagct
     3241 ggacggcgtg gagtctgacg tacaggaaga ctgcgagcgg gttaacgaca tcttgttgaa
     3301 agcgggcgcg actgacgtcc gtctggcaca ggacgaagca gagcgcgtac gtttctgggc
     3361 cggtcgcaaa aatgcgttcc cggcggtagg acgtatctcc ccggattact actgcatgga
     3421 tggcaccatc ccgcgtcgcg ccctgcctgg cgtactggaa ggcattgccc gtttatcgca
     3481 gcaatatgat ttacgtgttg ccaacgtctt tcatgccgga gatggcaaca tgcacccgtt
     3541 aatccttttc gatgccaacg aacccggtga atttgcccgc gcggaagagc tgggtgggaa
     3601 gatcctcgaa ctctgcgttg aagttggcgg cagcatcagt ggggaacatg gcatcgggcg
     3661 agaaaaaatc aatcaaatgt gcgcccagtt caacagcgat gaaatcacga ccttccatgc
     3721 ggtcaaggcg gcgtttgacc ccgatggttt gctgaaccct gggaaaaaca ttcccacgct
     3781 acaccgctgt gctgaatttg gtgccatgca tgtgcatcac ggtcatttac ctttccctga
     3841 actggagcgt ttctgatgct acgcgagtgt gattacagcc aggcgctgct ggagcaggtg
     3901 aatcaggcaa ttagcgataa aacgccgctg gtgattcagg gcagcaatag caaagccttt
     3961 ttaggtcgcc ctgtcaccgg gcaaacgctg gatgtgcgtt gtcatcgcgg cattgttaat
     4021 tacgacccga ccgagctggt gataaccgcg cgtgccggaa cgccgctggt ggcgattgaa
     4081 gcggcgctgg agagcgccgg gcaaatgctc ccctgcgagc cgccgcatta tggtgaagaa
     4141 gccacctggg gcgggatggt cgcctgcggg ctggcggggc cgcgtcgccc gtggagcggt
     4201 tcggtccgcg attttgtcct cggcacgcgc atcattaccg gcgctggaaa acatctgcgt
     4261 tttggtggcg aagtgatgaa aaacgttgcc ggatacgatc tctcacggtt aatggccgga
     4321 agctacggtt gtcttggcgt gctcactgaa atctcgatga aagtgttacc gcgaccgcgc
     4381 gcctccctga gcctgcgtcg ggaaatcagc ctgcaagaag ccatgaacga aatcgcccag
     4441 tggcaactcc agccgctacc cattagtggc ttatgttact tcgacaatgc gttgtggatc
     4501 cgccttgagg gcggcgaagg atcggtaaaa gcggcgcgtg aactgctggg gggcgaagag
     4561 gttgcgggtc agttctggca gcaattgcgt gaacaacaac tgccgttctt ctcgttacca
     4621 ggtaccttat ggcgcatttc attacccagc gatgcgccga tgatggattt acccggcgag
     4681 ctactgatcg actggggcgg agcgttacgc tggctgaaat cgacagccga ggacaatcaa
     4741 atccatcgca tcgcccgcaa cgctggcggt catgcgaccc gctttagtgc cggagatggt
     4801 ggctttgccc cgctatcggc tcctttattc cgctatcacc agcagcttaa acagcagctc
     4861 gacccttgcg gcgtgtttaa ccccggtcgc atgtacgcgg aactttgagg agcaggctat
     4921 gcaaacccaa ttaactgaag agatgcggca gaacgcgcgc gcgctggaag ccgacagcat
     4981 cctgcgcgcc tgtgttcact gcggattttg taccgcaacc tgcccaacct atcagcttct
     5041 gggcgatgaa ctggacgggc cgcgcgggcg catctatctg attaaacagg tgctggaagg
     5101 caacgaagtc acgcttaaaa cacaggagca tctcgatcgc tgcctcactt gccgcaattg
     5161 tgaaaccacc tgtccttctg gtgtgcgcta tcacaatttg ctggatatcg ggcgtgatat
     5221 tgtcgagcag aaagtaaaac gcccactgcc ggagcgaata ctgcgcgaag gattgcgcca
     5281 ggtagtgccg cgtccggcgg tcttccgtgc gctgacgcag gtagggctgg tgctgcgacc
     5341 gtttttaccg gaacaggtca gagcaaaact gcctgctgaa acggtgaaag ctaaaccgcg
     5401 tccgccgctg cgccataagc gtcgggtttt aatgctggaa ggctgcgccc agcctacgct
     5461 ttcgcccaac accaacgcgg caactgcgcg agtgctggat cgtctgggga tcagcgtcat
     5521 gtcagctaac gaagcaggct gttgtggcgc ggtggactat catcttaatg cgcaggagaa
     5581 agggctggca cgggcgcgca ataatattga tgcctggtgg cccgcgattg aagcaggtgc
     5641 cgaggcaatt ttgcaaaccg ccagcggttg cggcgcgttt gtcaaagagt acgggcagat
     5701 gctgaaaaac gatgcgttat atgccgataa agcgcgtcaa gtcagtgaac tggcggtcga
     5761 tttagtcgag cttctgcgcg aggaaccgct ggaaaaactg gcaattcgcg gcgataaaaa
     5821 actggccttc cactgcccgt gtaccctgca acatgcgcaa aagctgaacg gcgaagtgga
     5881 aaaagtgttg cttcgtcttg gatttacctt aacggacgtt cccgacagcc atctgtgctg
     5941 cggttcagcg ggaacatatg cgttaacgca tcccgatctg gcacgccagc tgcgggataa
     6001 caaaatgaat gcgctggaaa gcggcaaacc ggaaatgatc gtcaccgcca acattggttg
     6061 ccagacgcat ctggcgagcg ccggtcgtac ctctgtgcgt cactggattg aaattgtaga
     6121 acaagccctt gaaaaggaat aaaaaaatga aaactaaagt cattcttagc cagcaaatgg
     6181 cgagtgcaat tattgccgca ggtcaggaag aggcgcagaa aaataactgg tctgtttcca
     6241 ttgctgttgc cgatgacggc ggtcatctgc tggcgttaag tcgcatggac gattgcgcgc
     6301 cgattgcggc ttacatctcc caggagaaag cgcgtaccgc cgcgctgggg cgtcgtgaaa
     6361 ctaagggcta tgaagagatg gtgaacaacg gacgtaccgc gttcgtgact gcgccgttac
     6421 tgacgtcgct ggaaggtggc gtaccggttg ttgttgatgg gcaaattatt ggtgccgtgg
     6481 gcgtttctgg tttaaccgga gcacaggatg cgcaggtcgc gaaagcggca gcagcggtgt
     6541 tggcgaaata agcgaaaacg aggagataaa caatgagtca aaccataacc cagggccgtt
     6601 tacgcattga cgccaatttt aaacgttttg tggatgaaga agttttaccg ggaacagggc
     6661 tggacgctgc ggcgttctgg cgcaattttg atgaaatcgt tcacgatctg gcaccagaaa
     6721 atcgtcagtt gctggcagag cgcgatcgca ttcaggcggc gcttgatgag tggcatcgca
     6781 gcaatccggg gccggtaaaa gataaagcgg cctataaatc tttcctgcgt gaactgggct
     6841 acctggtgcc gcaaccggag cgcgtgacgg tggaaaccac gggcattgac agcgaaatca
     6901 ccagtcaggc ggggccacag ctggtggttc cggcaatgaa cgcccgctac gcgctgaacg
     6961 cggcgaacgc tcgctggggc tcactgtacg atgcgttata cggcagcgac atcatcccgc
     7021 aggaaggggc gatggtcagc ggctacgatc cgcaacgcgg tgagcaggtt atcgcctggg
     7081 ttcggcgttt cctcgatgaa tctctaccgc tggaaaacgg cagctatcag gatgtggtgg
     7141 cgtttaaggt ggtcgataaa caattacgca tccagttgaa aaatggtaaa gaaaccacgt
     7201 tacgtacccc ggcgcagttt gtcggttacc gtggcgatgc cgctgcgccg acctgcattt
     7261 tgctgaaaaa taacggcctg catattgaac tgcaaattga tgccaacggg cggattggca
     7321 aagacgatcc ggcgcacatc aacgatgtta tcgtcgaagc ggccatcagt accattctcg
     7381 actgcgaaga ttcggtcgcg gcggttgatg cggaagataa aatcctgctg taccgcaatc
     7441 tgctgggcct gatgcagggg actctgcaag agaaaatgga taaaaacggt cggcaaatcg
     7501 tgcgtaaact gaatgatgat cgtcagtaca ccgccgccga tggctctgaa atttctctgc
     7561 acggacgctc gttgctgttt atccgcaacg tgggtcattt gatgaccatt cctgtgattt
     7621 gggacagcga aggcaatgaa atcccggaag gcattcttga tggcgtcatg actggcgcga
     7681 ttgccctcta tgatttaaaa gtgcagaaaa actcgcgcac tggcagcgtc tatattgtga
     7741 aaccgaaaat gcacggtccg caggaagtgg cgttcgccaa caaactgttt acccgcattg
     7801 agacaatgct cggtatggca ccgaataccc tgaaaatggg cattatggat gaagaacgtc
     7861 ggacctcgct gaacttgcgt agctgtatcg ctcaggcgcg taaccgcgtg gcgttcatca
     7921 ataccggttt cctcgaccgt accggcgatg aaatgcattc ggtgatggaa gctggcccga
     7981 tgctgcgtaa aaaccagatg aaatcgacgc cttggatcaa agcctacgaa cgtaataacg
     8041 tgctttccgg cctgttctgt gggctgcgcg gtaaagcgca aatcggtaaa ggcatgtggg
     8101 caatgccgga cctgatggca gacatgtaca gccagaaggg cgaccaactg cgtgccgggg
     8161 caaacacagc ctgggttccg tcgccaactg ccgctacgct ccatgcgatg cactaccacc
     8221 aaaccaacgt acagagcgtg caagccaaca ttgcccagac cgagttcaat gctgaatttg
     8281 aaccgctgct ggacgatctg ctgactattc cggtggctga aaacgctaac tggtcggtgg
     8341 aagagatcca acaagagctg gataacaacg tgcaggggat tctggggtac gtggtgcgct
     8401 gggtggagca ggggattggt tgttcaaaag tgccggatat tcacaatgtg gcgctgatgg
     8461 aagaccgcgc aacgctgcgt atctccagcc agcatatcgc caactggtta cgtcacggta
     8521 ttctgaccaa agaacaggtg caggcgtcgc tggagaatat ggcgaaagtg gttgatcagc
     8581 aaaacgctga cgatccggct tatcgtccga tggcggggaa tttcgctaac tcgtgtgctt
     8641 ttaaagctgc cagcgattta atcttcctcg gcgtgaaaca gccaaacggc tataccgaac
     8701 cgttattaca cgcctggcgt ttacgcgaaa aagaaagtca ttaatagcgt caaaaaagcc
     8761 ccggcaagtt ttattgtcgg ggctatgata gtaactgcgg tagtacattt atcccggaaa
     8821 taaccggagc gattatcagg gtttaacaat attaaatacc cgtagcgcat tactagcggg
     8881 cctaaaacaa caatatggac atcttaacga tactctgcgc ctgcgtgtgc ggaacagaaa
     8941 cccttacccg atatacttgt tatgccagag gtagcaattg cgttagcggc gtactgttgc
     9001 tgtaaagtat aacgtctata ttttacagtt cagtcctctt ttgcttatta caaccttaag
     9061 tatatcaagc atataaagat aataagagac tgaacaatat ggttacctgg acccaaatgt
     9121 atatgccaat gggaggactg gggctatccg ctctggtcgc cctgatcccg ataatattct
     9181 tcttcgttgc actcgcggta ttacgtctga aaggacatgt cgctggagca ataaccctta
     9241 tattatctat cctgattgca atattcgcct ttaaaatgcc gattgatatg gcttttgctg
     9301 ctgcgggcta tggctttatt tatggattat ggcctattgc gtggattatt gtcgcggcgg
     9361 tgttcctcta taaattaacc gttgccagcg gtcagttcga tattatccgc agctcggtta
     9421 tctccatcac cgacgatcag cgtttgcagg tgttactgat tggtttctcc tttggtgcgt
     9481 tgctggaagg agcggctggc tttggtgcgc cggtggcgat taccggtgcg ctgctggtgg
     9541 gcctgggctt caaaccgtta tacgcggcgg ggctgtgtct gattgccaac actgcgccag
     9601 tggcgtttgg tgcgttgggc gtgccgattc tggtcgccgg tcaggtaacg ggaatcgatc
     9661 cgttccacat tggcgcaatg gcgggacgtc agttaccgtt cctgtcggtt cttgtgccgt
     9721 tctggctggt agcaatgatg gacggctgga aaggggtgaa agagacgtgg ccagcggcgc
     9781 tggttgctgg gggaagcttc gctgtcactc agttctttac ctctaactat attggtccgg
     9841 aactgccgga tattacttcg gcgctggtga gtatcgtctc actcgcttta ttccttaaag
     9901 tctggcggcc gaaaaatacc gaaacggcaa tcagcatggg gcaatccgca ggtgcgatgg
     9961 tggtaaataa gccatcttct ggcggtcccg tgccttcaga atatagtctg gggcaaatca
    10021 ttcgtgcgtg gtcaccgttt ttaatcttaa cggtgctggt caccatctgg accatgaagc
    10081 cgtttaaagc gttatttgct ccgggcggcg cgttttattc actggtgatt aatttccaga
    10141 tccctcattt gcatcaacaa gtgttgaaag cggcacccat tgtcgcccaa ccaacgccaa
    10201 tggatgcggt gtttaaattc gaccctctct cggctggcgg caccgctatt tttattgcgg
    10261 cgattatctc tatcttcatc ctcggcgtgg gcatcaagaa agggattggc gtctttgccg
    10321 aaacgctaat tagtctgaag tggccgatat tgtcgattgg catggtgctg gcgttcgcct
    10381 tcgtcaccaa ctattccggc atgtccacca cgctggcgct ggtactggca ggtacaggcg
    10441 tgatgttccc gtttttctca ccgttcctcg gctggctggg ggtattcctt accggctcgg
    10501 acacttcttc aaacgccctg tttggttcac tgcaatcgac tacggcgcag caaatcaacg
    10561 tctctgacac tctgctggtg gcagcaaata ccagcggcgg cgtaactggc aagatgatct
    10621 ccccgcaatc tatcgccgtg gcctgcgccg cgacgggcat ggtgggccga gaatctgaac
    10681 tattccgcta caccgtgaag cacagtctga tttttgccag cgttatcggc gttatcacgt
    10741 tgttgcaggc gtatgtgttt actggaatgt tggtctcgta aatcaataat gccggatgat
    10801 cgttaatatc atccggcttc atttacatta ttctgtctta ttaattgaaa attatttctc
    10861 gctttattat ccatgcggca ataatgtttt gtgttcagat aacctgataa ataattaaga
    10921 gcgtgagaac atctattttt ttatcacgca aaacaagtct gtattaatta tgttcgcttg
    10981 atgagcaaac accgttctat ctgttgcttt tgcaatctta atcgttaaaa ctaccaacga
    11041 atttatatag ttgcgttgtg aaatgttgtt aattttttgt ttattgaaat ttcgta
//
LOCUS       DAZUDJ010000116        11052 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.117, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000116 DAZUDJ010000000
VERSION     DAZUDJ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11052
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.117"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1087
                     /locus_tag="ACHY1N_004582"
     CDS             <1..1087
                     /locus_tag="ACHY1N_004582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HFS4046761.1"
                     /translation="WENLHALKEKRLNGMPKTTPKSDQVIMLQNQYVREMRKYGVRGL
                     RYDAAKHSKHEQIERSITPPLKNYNERLHNTNLFNPKYHEKVVMNYMEYLVTCQLDEE
                     QMSSLLYERDDLSAIDFSLLMKTIKAFSFGGDLQTLASKPGSTISSIPSKRRILINIK
                     HDFPNNGNIFNDFLFNHQQDEQLAMAYMAALPFSRPLVYWDGQVLKSTTEIKNYDGST
                     RVGDEAWLNKGCSTYQQLYNEFHALYIDKAGIWSAFEGVFATKNVLAFSRGDSVNINH
                     SPHDGLIIINKGNEEVEGAWPNKLQPGKYKNMGSNSVNIIIINTRKIIPPGKAFMLRG
                     GTLNINIPGRSALLLGKTGEPLNYLYL"
     gene            1423..2400
                     /gene="glaH"
                     /locus_tag="ACHY1N_004583"
     CDS             1423..2400
                     /gene="glaH"
                     /locus_tag="ACHY1N_004583"
                     /EC_number="1.14.11.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417145.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050498 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, with 2-oxoglutarate as one donor, and
                     the other dehydrogenated [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutarate dioxygenase GlaH"
                     /protein_id="HFS4046762.1"
                     /translation="MNALTAVQNNAVDSGQDYSGFTFIPSAQSPRLLELTFTEQTTKQ
                     FLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGI
                     DDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNIDNSDSYLRQPHRVMELH
                     NDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHYFRHPLARRPMRFAAPP
                     SKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYASNHYQTHQ"
     gene            2420..3688
                     /gene="lhgO"
                     /locus_tag="ACHY1N_004584"
     CDS             2420..3688
                     /gene="lhgO"
                     /locus_tag="ACHY1N_004584"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417146.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HFS4046763.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESGPACHQTG
                     HNSGVIHAGVYYTPGSLKAQFCLAGNRATKAFCDQNGIRFDNCGKMLVATSPLEMERM
                     RALWERTAANGIEREWLNADELREREPNITGLGGIFVPSSGIVSYREVTAAMAKIFQD
                     RGGEIIYNAEVSALNEHKNGVVIRTSQGGEYEASTLISCSGLMADRLVKMLGLEPGFI
                     ICPFRGEYFRLAPEHNQIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKR
                     EGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKSGYLRLVQKYCPRLS
                     LSDLQPRPAGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIVSK
                     VQTLLASQSNPGRTLRAARSVDALHAAFNQ"
     gene            3711..5159
                     /gene="gabD"
                     /locus_tag="ACHY1N_004585"
     CDS             3711..5159
                     /gene="gabD"
                     /locus_tag="ACHY1N_004585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009013 - succinate-semialdehyde
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_process: GO:0009450 - gamma-aminobutyric acid catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HFS4046764.1"
                     /translation="MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPK
                     MGADETRAAIDAANRALPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPA
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGIPAGVFNVVTGSAGAVGN
                     ELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAVSKLHIGDGLDKGVTIGPLIDE
                     KAVAKVEEHIADALEKGARVVCGGKADERGGNFFQPTILVDVPANAKVSKEETFGPLA
                     PLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            5173..6453
                     /gene="gabT"
                     /locus_tag="ACHY1N_004586"
     CDS             5173..6453
                     /gene="gabT"
                     /locus_tag="ACHY1N_004586"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003867 - 4-aminobutyrate transaminase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009448 - gamma-aminobutyric acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HFS4046765.1"
                     /translation="MSSNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYL
                     DFAGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKVPGNFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMG
                     LMPGHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYASS
                     PAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPL
                     AGVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKANDLGQKLKDG
                     LLAIAEKHPEIGDVRGLGAMIAIELFEDGDHNKPDAKLTAEIVARARDKGLILLSCGP
                     YYNVLRILVPLTIEDAQIRQGLEIISQCFDEAKQ"
     gene            6691..8091
                     /gene="gabP"
                     /locus_tag="ACHY1N_004587"
     CDS             6691..8091
                     /gene="gabP"
                     /locus_tag="ACHY1N_004587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015185 - gamma-aminobutyric acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HFS4046766.1"
                     /translation="MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFW
                     VLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKV
                     IAILAFIFLGAVAISGFYPYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSV
                     LELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTP
                     YVAVLLSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAE
                     GSEIRLRMWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMAR
                     WKKLVLWQKTPVHNTR"
     gene            8112..8774
                     /gene="csiR"
                     /locus_tag="ACHY1N_004588"
     CDS             8112..8774
                     /gene="csiR"
                     /locus_tag="ACHY1N_004588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HFS4046767.1"
                     /translation="MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLR
                     EALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDARANMEAMLVSLAIARGGDEWEA
                     DVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSHYLLQMRERLFDLAAR
                     YRFIWLRRTVLSVEMLEDKHDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMA
                     GN"
     gene            complement(8775..9224)
                     /gene="kbp"
                     /locus_tag="ACHY1N_004589"
     CDS             complement(8775..9224)
                     /gene="kbp"
                     /locus_tag="ACHY1N_004589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium binding protein Kbp"
                     /protein_id="HFS4046768.1"
                     /translation="MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLSKTGIPDAD
                     KVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGIASVDDQVKTATPATASQFYTVK
                     SGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE"
     gene            complement(9308..9466)
                     /gene="yqaE"
                     /locus_tag="ACHY1N_004590"
     CDS             complement(9308..9466)
                     /gene="yqaE"
                     /locus_tag="ACHY1N_004590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HFS4046769.1"
                     /translation="MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIH
                     AFWVQTRD"
     gene            9649..9948
                     /gene="ygaV"
                     /locus_tag="ACHY1N_004591"
     CDS             9649..9948
                     /gene="ygaV"
                     /locus_tag="ACHY1N_004591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFS4046770.1"
                     /translation="MTELAQLQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGEL
                     TRITGLSASATSQHLARMRDEGLIDSQRDAQRILYSIKNEAVNAIIATLKNVYCP"
     gene            9958..10482
                     /gene="ygaP"
                     /locus_tag="ACHY1N_004592"
     CDS             9958..10482
                     /gene="ygaP"
                     /locus_tag="ACHY1N_004592"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001461399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YgaP"
                     /protein_id="HFS4046771.1"
                     /translation="MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLS
                     VLEQSGLPPKLRREQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKRAGLP
                     VAVNKSQPLPLMRQVQIAAGGLILIGVVLGYTVNSGFFLLSGFVGAGLLFAGISGFCG
                     MARLLDKMPWNQRT"
     gene            complement(10529..10933)
                     /gene="stpA"
                     /locus_tag="ACHY1N_004593"
     CDS             complement(10529..10933)
                     /gene="stpA"
                     /locus_tag="ACHY1N_004593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HFS4046772.1"
                     /translation="MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEE
                     EQQQRELAERQEKISTWLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFTDV
                     NGETKTWTGQGRTPKPIAQALAEGKSLDDFLI"
BASE COUNT         2674 a         2764 c         2912 g         2702 t
ORIGIN      
        1 atgggaaaac ctccatgcat taaaagaaaa gcgtttaaat ggaatgccta aaacaacccc
       61 caaaagtgac caggttatta tgctgcaaaa tcaatacgtt cgtgaaatgc gaaaatatgg
      121 cgtacgaggt ttacgttacg atgcagcaaa acactcaaaa catgaacaaa tagaaagatc
      181 aataacccca ccgcttaaaa attataatga gcggttacac aatactaatt tatttaaccc
      241 aaaatatcat gaaaaagtcg ttatgaatta catggaatat ctggtaactt gtcagttgga
      301 tgaagaacaa atgtcatcgc tgctttatga aagagatgat ttaagcgcca ttgatttttc
      361 attgctcatg aagacgataa aagctttttc atttggtggc gatctccaaa cccttgcatc
      421 aaaaccgggt tccacaatct caagcatccc atcaaaaaga cggatattga ttaacattaa
      481 acacgatttt cctaacaatg gcaatatttt caatgacttt ctatttaacc atcaacaaga
      541 tgaacaatta gcaatggcat atatggccgc tctcccgttc agcaggcctt tagtttactg
      601 ggatggccaa gtattaaaat caacgactga aattaaaaat tatgatgggt cgacgcgtgt
      661 tggcgatgag gcgtggctta ataaaggttg ctctacctat cagcagctct acaatgaatt
      721 ccacgcatta tatatagata aagcaggaat atggagcgca tttgagggtg tatttgcaac
      781 taaaaacgtt ctggccttta gtcgtgggga ttctgtgaac attaatcact ctcctcatga
      841 tggactaatt ataataaata aaggaaacga agaagttgaa ggtgcctggc ctaacaaatt
      901 gcaacctgga aaatataaaa acatggggag taatagcgtt aacattatta ttattaatac
      961 ccgaaaaatt atcccccctg gtaaagcatt tatgcttaga ggcggaactc taaatatcaa
     1021 tattcctggg cgtagcgctc ttcttttagg gaaaacagga gaaccgctga actatctcta
     1081 tttgtaattt aatgttatat ctgccccgct aaaacggggc agataatatg tttagtttac
     1141 taacggtcat tttgcattga agccatttac tgttttttat cgaccagata atctgttctc
     1201 tgatggtaac tccccctaac ctattgcttt agttattcat ttcctgtctc actttgcctt
     1261 aataccctac gttaaatgtt actaatttgt tgcttttgat cacaataaga aaacaatatg
     1321 tcgcttttgt gcgcattttt cagaaatgta gatattttta gattatggct acgaaatgag
     1381 catcgccatg tcaccctaca tctcataaga ggatcgcttc tgatgaatgc actgaccgcc
     1441 gtacaaaata acgctgtcga ttcaggccag gactatagcg gattcacttt catcccgtcg
     1501 gcgcaatccc cgcgtctgct ggaacttacc ttcaccgaac agacgaccaa acagtttctc
     1561 gaacaggttg ccgaatggcc cgtacaggcg ctggagtaca aatcctttct gcgttttcgg
     1621 gtaggcaaaa ttcttgacga tctgtgtgcg aatcagctgc aaccattgct gttgaagacc
     1681 ctgctaaacc gtgctgaagg tgcgctgttg atcaatgcgg tgggtatcga tgatgtggcg
     1741 caggcagatg agatggtgaa gctggcaacg gcggtagcgc atctgattgg tcgctcaaat
     1801 ttcgatgcga tgagcggtca gtattacgcg cgtttcgtgg tgaaaaatat cgataactca
     1861 gacagctatc tgcgtcagcc gcaccgcgtg atggaactgc acaacgacgg cacgtatgtc
     1921 gaagagatca ccgattacgt gctgatgatg aaaatcgatg agcaaaacat gcagggtgga
     1981 aattcgttgc tgctgcatct cgatgactgg gaacatctgg accactattt ccgccatcca
     2041 ctggcgcgtc gcccgatgcg ctttgccgcg ccgccgagca aaaacgtcag caaagatgtt
     2101 ttccatccag tgttcgacgt tgatcaacag ggtcgcccgg tgatgcgcta tatcgaccag
     2161 ttcgtccagc caaaagattt tgaagaaggc gtgtggttga gcgagctttc cgatgccatt
     2221 gaaaccagca aaggcattct ttctgtaccc gttcccgttg gcaaattcct gttgataaac
     2281 aacctattct ggctgcacgg tcgcgaccgc tttactccgc acccggatct gcgccgtgaa
     2341 ctgatgcgtc agcgtggcta tttcgcttac gcctctaacc actaccagac gcatcagtaa
     2401 gcgcaaagga attgagcgga tgtatgattt tgtgattatt ggcggcggca tcatcggcat
     2461 gtcgaccgcc atgcaactga ttgatgtcta tccggatgcc cgcattgcgt tgctggaaaa
     2521 agagtccggc ccggcctgtc accagacggg ccacaacagc ggcgtgatcc atgccggggt
     2581 ctattacacg cccggtagcc tgaaggcaca gttttgcctg gcgggaaacc gcgccactaa
     2641 agccttttgc gatcaaaacg gcattcgctt tgacaactgc ggcaagatgc tggtcgccac
     2701 gtctccgctc gaaatggaac ggatgcgcgc cttatgggaa cgcacagcgg cgaacggtat
     2761 cgagcgcgaa tggctaaacg ccgacgaact gcgcgagcgc gaaccgaata tcaccgggct
     2821 cggcggtatt tttgtgccgt ccagcggcat tgtcagctac cgcgaagtga cagcggcgat
     2881 ggcaaaaatc tttcaggaca gaggcggcga gattatttat aacgccgaag tcagcgccct
     2941 taatgagcat aaaaacggcg tggtgatacg taccagtcag ggcggtgaat atgaagcatc
     3001 gacgctgatt agctgttccg ggctgatggc tgaccggctg gtgaaaatgc tcggactcga
     3061 accgggcttt atcatctgcc cgttccgtgg cgagtatttc cgccttgcgc cggagcataa
     3121 ccagattgtt aaccacctga tttaccccat ccccgacccg gcaatgccgt ttttgggcgt
     3181 gcatctcacc cgcatgatcg acggcagcgt gaccgtcggg ccaaacgcgg tgctggcttt
     3241 caaacgtgaa ggctatcgca agcgcgactt ctcatttagc gacacgctgg aaattttggg
     3301 ctcgtcgggg attcgccggg tgctgcaaaa ccatctacgc tcaggactgg gcgagatgaa
     3361 aaactcgctg tgcaaaagcg gctatctgcg gctggtgcaa aagtattgtc cccggctttc
     3421 gttaagcgat ctccagccca ggcccgccgg tgtgcgggcg caggcggtat cgccggacgg
     3481 caagctgatt gacgattttc tgtttgtcac caccccgcgc acgatccaca cctgcaatgc
     3541 gccctccccg gcagcgacat cagcaattcc tattggtgcg catattgtca gcaaggtaca
     3601 aacgctgttg gcaagccaga gtaaccccgg acgcacgctg cgagcggcac gtagtgtgga
     3661 tgccttacac gccgcattta atcaataacc tttgaaaaca ggacgtaaca atgaaactta
     3721 acgacagtaa cttattccgc cagcaggcgt tgattaacgg ggaatggctg gacgccaaca
     3781 atggcgaggt catcgacgtc accaatccgg cgaacggcga caagctgggt agcgtgccga
     3841 aaatgggcgc ggatgaaacc cgcgccgcta tcgacgccgc caaccgcgcc ctgccagcct
     3901 ggcgcgcgct caccgccaaa gaacgcgcca ccattctgcg caactggttc aatttgatga
     3961 tggagcatca ggacgattta gcgcgcctga tgaccctcga acagggtaaa ccgctggctg
     4021 aagcgaaagg cgaaatcagc tacgccgctt cctttattga gtggtttgcc gaagaaggca
     4081 aacgcattta tggcgacacc attcccggtc atcaggccga taagcgcctg attgttatca
     4141 agcagccgat tggcgttacc gccgccatca cgccgtggaa cttcccggcg gcgatgatta
     4201 cccgtaaagc cggtccggcg ctggcggcag gctgcacgat ggtgctgaaa cccgccagtc
     4261 agacgccgtt ctctgcgctg gcgctggcgg agctggcgat tcgcgcgggc attccggctg
     4321 gcgtatttaa cgtggtcacc ggttcggcgg gcgcggtggg taacgaactg accagcaacc
     4381 cgctggtgcg caaactgtcg tttaccggtt cgaccgaaat tggccgccag ttaatggaac
     4441 agtgcgcgaa agacatcaag aaagtgtcgc tggagctggg cggcaacgcg ccgtttatcg
     4501 tctttgatga tgccgatctc gacaaagccg tggaaggcgc actggcctcg aaattccgca
     4561 acgccgggca aacctgcgtc tgcgccaacc gtttatacgt gcaggacggc gtgtatgacc
     4621 gctttgccga aaaattacag caggcggtga gcaaactgca catcggcgac gggctggata
     4681 aaggcgtcac catcgggccg ctgatcgatg aaaaagcggt agcaaaagtg gaagagcata
     4741 ttgccgatgc gctggagaaa ggtgcgcgtg tggtttgcgg cggtaaagcg gatgaacgcg
     4801 gcggcaactt cttccagccg accattctgg tggacgttcc agccaacgcc aaagtgtcga
     4861 aagaagagac gttcggcccc ctcgccccac tgttccgttt taaagatgaa gccgatgtga
     4921 ttgcgcaagc caatgacacc gagtttggcc ttgccgccta tttctacgcc cgtgatttaa
     4981 gccgcgtctt ccgcgtgggc gaagcgctgg agtacggcat cgtcggcatc aataccggca
     5041 tcatttccaa tgaagtggcc ccgttcggcg gcattaaagc ctcgggtctg ggtcgtgaag
     5101 gttcgaagta tggcatcgaa gattacttag aaatcaaata tatgtgcatc ggtctttaac
     5161 tggagaacgc gaatgagcag caataaagag ttaatgcagc gccgcagtca ggcgattccc
     5221 cgtggtgttg ggcaaattca cccgattttc gctgaccgcg cggaaaactg ccgggtgtgg
     5281 gacgttgaag gccgtgagta tcttgatttc gcgggcggga ttgcggtgct caataccggg
     5341 cacttgcatc cgaaagtggt ggctgcggtg gaagcgcagt tgaaaaaact gtcgcacacc
     5401 tgcttccagg tgctggccta cgagccgtat ctggagctgt gcgagattat gaatcagaag
     5461 gtgccaggca attttgccaa gaaaacgctg ctggtcacca caggttctga agcggtggaa
     5521 aacgcggtga aaatcgcccg cgccgccacc aaacgtagcg gcaccatcgc ttttagcggc
     5581 gcgtatcacg ggcgcacgca ttacacgctg gcgctgaccg gcaaggtgaa tccgtactct
     5641 gcgggcatgg ggctgatgcc gggtcatgtt tatcgcgcgc tttatccttg cccgctgcac
     5701 ggcataagcg aggatgacgc tatcgccagc atccaccgga tcttcaaaaa tgatgccgcg
     5761 ccggaagata tcgccgccat cgtgattgag ccggttcagg gcgaaggcgg tttctacgcc
     5821 tcgtcgccag cctttatgca gcgtttacgc gctctgtgtg acgagcacgg gatcatgctg
     5881 attgccgatg aagtgcagag cggcgcgggg cgtaccggca cgctgtttgc gatggagcag
     5941 atgggcgttg cgccggatct taccaccttt gcgaaatcga tcgcgggcgg cttcccgctg
     6001 gcgggcgtca ccgggcgcgc ggaagtaatg gatgccgtcg ctccaggcgg tctgggcggc
     6061 acctatgcgg gtaacccgat tgcctgcgtg gctgcgctgg aagtgttgaa ggtgtttgag
     6121 caggaaaatc tgctgcaaaa agccaacgat ctggggcaga agttgaaaga cggattgctg
     6181 gcaatagccg aaaaacaccc ggagatcggc gacgtacgcg ggctgggggc gatgatcgcc
     6241 attgagctgt ttgaagacgg cgatcacaac aagccggacg ccaaactcac cgccgagatc
     6301 gtggctcgcg cccgcgataa aggcctgatt cttctctcct gcggcccgta ttacaacgtg
     6361 ctgcgcatcc ttgtaccgct caccattgaa gacgctcaga tccgtcaggg tctggagatc
     6421 atcagccagt gttttgatga ggcgaagcag tagcgccgct cctatgccgg aggcgacgct
     6481 gcgcgtcttg tccggcctac ggggatccag gtcggataag gcgtttacgc cgcatccgac
     6541 aatctgtacg tgaacaggaa gaaatctatg ttggccgggt aaggcggagc cgctctccgg
     6601 caaaaagaat caataacaat tatacgcgtg acccggcgcg ggaaatgtcg gggcgctctc
     6661 ccaagtgaca cactttcgag aggattcagg atggggcaat catcgcaacc acatgagtta
     6721 ggcggcgggc tgaagtcacg ccacgtcacc atgttgtcta ttgccggtgt tatcggcgca
     6781 agtctgtttg tcggttccag cgtcgccatc gccgaagcgg gcccggcggt attactggcc
     6841 tatctgttcg ccgggctact ggtggttatg attatgcgga tgttggcgga aatggcggtt
     6901 gccacgcccg ataccggttc gttttccacc tatgccgata aagccattgg tcgctgggcg
     6961 ggctatacca tcggctggtt gtactggtgg ttttgggtac tggttatccc gctggaagcc
     7021 aacatcgccg ccatgatcct gcactcatgg gttccaggca ttcccatctg gttattttcc
     7081 ctcgtcatta ccctcgcctt aactggcagt aacttattaa gcgttaaaaa ctacggcgaa
     7141 tttgagttct ggctggcgct gtgcaaagtc atcgctatcc tggcctttat tttccttggt
     7201 gcagtcgcaa ttagcggttt ttacccgtat gccgaagtga gcgggatctc aagattgtgg
     7261 gatagcggcg gctttatgcc caacggtttc ggtgcggtat taagcgcgat gttgatcacc
     7321 atgttctcgt ttatgggcgc agaaattgtc accattgccg ccgcggaatc cgacacgccg
     7381 gaaaaacata ttgtccgcgc caccaactcg gttatctggc gtatttctat cttctattta
     7441 tgttctattt ttgtcgtcgt ggcattaatt ccgtggaata tgcccggact aaaagccgtc
     7501 ggttcttatc gctcggtact ggaattgctc aatattcccc atgcgaaatt aatcatggac
     7561 tgcgtgatat tactttccgt aaccagttgc ctgaactcgg cgctgtatac cgcgtcaagg
     7621 atgctctact ccttaagccg tcgcggtgat gctcccgcgg taatgggtaa aatcaaccgc
     7681 agtaaaaccc cgtacgtggc ggtgttactc tccaccggcg cggcattctt aacggtggtg
     7741 gtgaactatt acgcgcctgc gaaggtattt aaatttctga tcgacagctc cggcgctatc
     7801 gccctgctgg tttatttagt catcgccgtt tcacagttgc ggatgcgcaa aattctgcga
     7861 gcagaaggaa gcgaaattcg cttgcgaatg tggctttatc cgtggctcac ctggctagtc
     7921 atcggcttta ttacctttgt gttggtagtg atgctattcc gtccggcgca acagttagaa
     7981 gtgatctcca ccggcttatt agcgataggg attatctgta ccgtgccaat tatggctcgc
     8041 tggaaaaagc tggtattgtg gcaaaaaaca cccgttcata atacgcgctg atcatgatca
     8101 ggagtcacac catgaccatt acgtctctgg atggctatcg ctggctgaag aacgatatta
     8161 ttcgcggtaa ttttcaaccg gatgaaaaat tacgaatgag tttgctgaca tcgcgttatg
     8221 cacttggcgt tgggccgtta cgggaagctc tttcgcaact ggtggcggaa cggctggtca
     8281 cggtggtgaa tcaaaaaggg tatcgggtgg cgtctatgtc agagcaggag ttgctcgata
     8341 ttttcgacgc ccgcgccaat atggaagcga tgttagtgag tctggcgatt gcccgcggtg
     8401 gcgatgagtg ggaggcagac gttctcgcaa aagcgcatct gctgagtaag cttgaggcct
     8461 gtgacgccag cgagaaaatg cttgatgagt gggatctgcg tcatcaggcg tttcatacgg
     8521 caattgtggc gggctgtggt tctcactatt tgctgcaaat gcgtgaacgg ttgtttgatc
     8581 tggcggcgcg ctatcgattt atctggctgc ggcgaacggt gctttcggta gaaatgctgg
     8641 aggataaaca cgatcagcac cagaccctga ctgcggcggt actggcgcga gataccgcgc
     8701 gcgccagtga gttaatgcgc cagcatttac tgacgccaat tcccattatc cagcaggcga
     8761 tggctggcaa ttaactactc ttccggaata cgcaacactt gccccggata aattttatcc
     8821 gggcttttta gcatcggttt attcgcttcg aagattttat tgtacagatt agcgttaccg
     8881 tagacctgtt tggaaatggc actcagagtg tcgccagact taacggtata aaactggctg
     8941 gcagtggctg gtgtcgccgt tttcacctga tcatcaacac tggcaatacc ggaaatattc
     9001 ccaaccgcaa caaggatttt ctccttcgcc tcctgactca ggccgtcacc agtgaccgtc
     9061 gctttgccgt cggcaatttg aatgttcact ttatcggcat caggtatacc ggttttgctc
     9121 agatgctcct gcaccttctt cgcctgatcg tctttatcgt gctgacctgt aaccgcgtcc
     9181 cagagttttt ctccggcatc tttcacaaaa ttgaacagac ccatagctac ctcattcgtt
     9241 aacggaaaca ctcagaaagt gtagcagagg aacgcggcgc gttaacgccg cgggggtgag
     9301 cacaggttta atcgcgggtt tgcacccaga acgcgtgaat caaaccgggg atatacccaa
     9361 gcagtgtcag cagaatatta ataatgaacg cccaaccgaa ccctttaccg agcagcacgc
     9421 cgagcggcgg cagaatgatg gtgatgacga ttctccagaa acccatatgt actccctata
     9481 agaaaattac tcattgttta aaaagagatt ttatctctta agcgtagtaa ttttagcgga
     9541 gcctgccagt ttcagcttac gcttttactc tcatttacgc tgctgaggct ggtatatgtt
     9601 gcatttttag tttagagttt acttaattta gaaaatactt aaataaatat gactgaactc
     9661 gcgcaattac aggccagtgc cgaacaggca gcggccttat tgaaagcaat gagccatcct
     9721 aaacgattgc tgattctgtg catgcttagc ggttcccccg gcaccagcgc gggagagctg
     9781 acgcgcatta ccggactgag tgcctctgcg acatcacagc atctcgctcg tatgcgggac
     9841 gaagggctta tcgacagcca acgggatgcc caacgcattc tatattccat taaaaatgag
     9901 gcggtaaatg ccattatcgc caccctgaaa aatgtctatt gtccgtaagg agtcactatg
     9961 gctttgacaa ccatttcgcc gcatgatgca caagaattaa tcgcacgcgg cgcaaagtta
    10021 atcgatattc gtgacgctga tgaatatctt cgtgaacata ttcctgaagc agatctggct
    10081 ccattatccg tgctggaaca gtcaggtctt ccacctaaat tacgtcgcga gcaaattata
    10141 ttccactgcc aggcaggtaa acgcaccagt aataacgccg ataaattagc agcgattgcc
    10201 gcccccgcag aaatattttt actcgaagat gggattgatg gctggaaaag agctggattg
    10261 ccagtagcgg taaataaatc tcaacccttg ccgttaatgc gccaggtgca gatcgctgcg
    10321 ggtggtttaa tattaatcgg cgttgtactg ggttataccg taaatagcgg tttcttctta
    10381 ttaagtggct ttgttggtgc cgggttactg tttgcaggaa tcagcggttt ttgtggaatg
    10441 gcaaggttgt tagataagat gccgtggaac caacgaactt gagaagcgac gccggacgcg
    10501 ccctagcagc gacatccggc ctcagtaatt agatcaggaa atcgtcgaga gatttacctt
    10561 ctgccagcgc ctgagcaatt ggcttcggtg tacggccctg accggtccag gttttagttt
    10621 caccgttaac atcggtgaat ttatatttcg ccggacgcgg ctggcgtttt ttaccagcgc
    10681 gtggtgcagc agcagagcta ttacctaata actcttccgg gttaattccg tcagccttca
    10741 tcagctccag ccaggtgcta attttttcct gacgctcagc cagttcacgc tgctgctgtt
    10801 cttcttcttc acgtctttct ttagtgacaa ccctgaattt ttcgagcatt tcttcaagaa
    10861 cgtcaatgga gaattcgcga gccatcgcac ggagagtgcg aatgttattt aaactttgta
    10921 acattacgga cataataaag aaaacctttt aacgccaaaa caaaaaagta tttcgtcgcg
    10981 tagtgtaagc gatcacttat tatatttcca caaaatttaa tctatttaca gtcctgtgcg
    11041 agattatttc ag
//
LOCUS       DAZUDJ010000117        10888 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.118, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000117 DAZUDJ010000000
VERSION     DAZUDJ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10888
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.118"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            52..1266
                     /gene="manD"
                     /locus_tag="ACHY1N_004594"
     CDS             52..1266
                     /gene="manD"
                     /locus_tag="ACHY1N_004594"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0016052 - carbohydrate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-mannonate dehydratase ManD"
                     /protein_id="HFS4046773.1"
                     /translation="MKIIAADVFVTCPGRNFVTLKITTESGLCGLGDATLNGRELSVA
                     SYLKDHLCPQLIGRDASRIEDIWQFFYKGAYWRRGPVTMSAISAIDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGRTIDEVLEDYAKHQQMGFKAIRVQCGVPGMQTTYG
                     LAKGKGLAYEPATKGLWPEEQLWSSEKYLDFTPKLFEAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRLFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTITHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCHAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHSWRFEEGYMHPGDEPGLGISFDEKLAAKYPYDPAYLP
                     VARLEDGTLWNW"
     gene            1333..2616
                     /locus_tag="ACHY1N_004595"
     CDS             1333..2616
                     /locus_tag="ACHY1N_004595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000382182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4046774.1"
                     /translation="MDVDVSTSVAGNKPQRIRRIQTVTLVLLFMAGIVNFLDRSSLSV
                     AGEAIRGELGLSATEFGVLLSAFSLSYGFSQLPSGILLDRFGPRIVLGAGLIFWSLMQ
                     ALTGMVNSFSHFILMRIGLGIGEAPFMPAGVKSITDWYAQKERGTALGIFNSSTVIGQ
                     AIAPPALVLMQLAWGWRTMFVIIGVAGILVGICWYAWYRNRAQFVLTDEERTYLSAPV
                     KPRPQLQFSEWLALFKHRTTWGMILGFSGVNYTGWLYIAWLPGYLQAEQGFSLAKTGW
                     VAASPFLAAAVGMWVNGIVVDRLAKKGYDLAKTRKTAIVCGLMMSALGTLLVVQSSSP
                     AQAVAFISMALFCVHFAGTSAWGLVQVMVSETKVASIAGIQNFGSFVFASFAPIVTGW
                     VVDTTHSFNLALVIAACVTFTGALCYFFIVKDRIE"
     gene            2868..3785
                     /gene="oxyR"
                     /locus_tag="ACHY1N_004596"
     CDS             2868..3785
                     /gene="oxyR"
                     /locus_tag="ACHY1N_004596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HFS4046775.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVG
                     PYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPL
                     FDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGS
                     PLRSRYEQLAEAIRARMDGHFDKVLKQAV"
     gene            complement(3768..5168)
                     /gene="sthA"
                     /locus_tag="ACHY1N_004597"
     CDS             complement(3768..5168)
                     /gene="sthA"
                     /locus_tag="ACHY1N_004597"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003957 - NAD(P)+ transhydrogenase
                     (Si-specific) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HFS4046776.1"
                     /translation="MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGG
                     CTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQ
                     GFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTH
                     PRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQE
                     MSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTD
                     SLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALV
                     KGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN
                     VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTM
                     AEAYRVAALNGLNRLF"
     gene            5499..6149
                     /gene="fabR"
                     /locus_tag="ACHY1N_004598"
     CDS             5499..6149
                     /gene="fabR"
                     /locus_tag="ACHY1N_004598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HFS4046777.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE"
     gene            6149..6508
                     /gene="yijD"
                     /locus_tag="ACHY1N_004599"
     CDS             6149..6508
                     /gene="yijD"
                     /locus_tag="ACHY1N_004599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
                     /protein_id="HFS4046778.1"
                     /translation="MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLV
                     LTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIM
                     VFWIGAKMRNRKQEVAE"
     gene            complement(6548..7648)
                     /gene="trmA"
                     /locus_tag="ACHY1N_004600"
     CDS             complement(6548..7648)
                     /gene="trmA"
                     /locus_tag="ACHY1N_004600"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030697 - tRNA
                     (uracil(54)-C5)-methyltransferase activity, S-adenosyl
                     methionine-dependent [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HFS4046779.1"
                     /translation="MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHY
                     RMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTK
                     IELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELY
                     CGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHKVERLALFDQFPYTHHMECGVLLTAK"
     regulatory      7762..7952
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            8017..9861
                     /gene="btuB"
                     /locus_tag="ACHY1N_004601"
     CDS             8017..9861
                     /gene="btuB"
                     /locus_tag="ACHY1N_004601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015420 - ABC-type vitamin B12 transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015889 - cobalamin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HFS4046780.1"
                     /translation="MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLA
                     PTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDG
                     VRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEI
                     SAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFL
                     SKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRY
                     NGELIKSQLITSYSHSKDYNYDPHFGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAG
                     VDWQKQTTTPGTGYVENGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVN
                     WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARN
                     AITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSL
                     WDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     gene            9806..10663
                     /gene="murI"
                     /locus_tag="ACHY1N_004602"
     CDS             9806..10663
                     /gene="murI"
                     /locus_tag="ACHY1N_004602"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFS4046781.1"
                     /translation="MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLL
                     PDLHYIYAFDNVAFPYGEKSEEFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPA
                     LREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEML
                     GSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPEAEQLLPVLQRYGFE
                     TLEKLAVLG"
BASE COUNT         2516 a         2595 c         2919 g         2858 t
ORIGIN      
        1 ggcgtaaaat taagtttgaa acgtctattt acaacacagg agattgcaat aatgaaaatt
       61 attgctgcag atgtttttgt tacttgccca gggcgtaatt tcgttacgct taaaataacc
      121 actgaaagcg gactttgtgg attaggagat gccacgttaa atggtcgcga attgtcggtc
      181 gcttcttatc tgaaagatca tctttgtcca caactaattg gccgcgatgc cagccgtatc
      241 gaagatatct ggcaattctt ttataaaggt gcttactggc gacgtggccc cgtcacgatg
      301 tcagccattt ctgccattga tatggcgttg tgggatatca aagctaaagc ggcaaatatg
      361 ccattgtatc aactgcttgg tggtgcttct cgcgaaggcg tgatggttta ttgccacacc
      421 accgggcgga cgattgatga agtccttgaa gactatgcaa agcaccagca gatgggcttt
      481 aaggcgattc gtgtgcagtg cggtgtaccg ggtatgcaaa ctacttatgg cctggcgaag
      541 ggcaaaggcc tggcgtatga accggcaacc aaaggcctgt ggccagaaga gcagttgtgg
      601 tcttcagaaa agtatctcga ttttacgccg aagttatttg aagcggtgcg taataagttc
      661 ggttttaacg aacatctgtt gcatgacatg caccatcgcc tgacccccat cgaagcggcg
      721 cgctttggga agagcattga ggattaccgt ctgttctgga tggaagatcc gacgcctgca
      781 gagaaccagg aatgttttcg tctgattcgc cagcataccg tgacgccgat tgcggtcggt
      841 gaagtgttta acagtatctg ggactgcaag cagttaatcg aagagcagct gattgactat
      901 attcgcacga cgatcaccca tgcaggcggc attaccggga tgcggcggat tgccgatttt
      961 gcatcgcttt atcaggtacg taccggttcg catggccctt cagatttatc gcctgtttgt
     1021 catgcggcgg cgctgcattt tgacctatgg gtaccaaatt ttggcgttca ggagtacatg
     1081 ggctattccg aacaaatgct tgaagttttc ccgcacagct ggcgcttcga ggaaggttat
     1141 atgcacccag gcgatgaacc ggggctgggt atttctttcg atgagaaact ggcggcgaaa
     1201 tatccgtatg acccggcgta tctccccgtc gcacgactgg aagatggcac attgtggaac
     1261 tggtaataac ggttcgctta attattttct gaatagtcat caaatcgatt aattccgctc
     1321 aaggagctaa aaatggacgt tgatgtgtca accagtgttg cgggtaataa accgcaacgg
     1381 attcgtcgta ttcagacagt gaccctggtt ttattattta tggcggggat cgttaatttt
     1441 ctcgaccgtt cgtcattgag cgtggcaggt gaagcgattc gtggcgagtt aggattatcg
     1501 gcgacagagt ttggtgtttt gctttctgca ttttctctgt cttatggttt ttcacaacta
     1561 ccttccggta ttttgctaga ccgctttggc ccacgaattg ttttaggcgc aggcttaata
     1621 ttctggtcat taatgcaggc attaacagga atggttaatt cttttagcca ctttatttta
     1681 atgcgtatcg gtctgggtat tggcgaagcg ccatttatgc ctgcgggagt aaagtcgatc
     1741 accgactggt atgcacaaaa agaacgcggc acggcgctgg ggatttttaa ctcatctacc
     1801 gttatcggtc aggctatcgc gcctcctgct cttgtattga tgcagctggc atggggctgg
     1861 cggacgatgt tcgttatcat cggcgtggca gggattctgg ttgggatctg ttggtacgcg
     1921 tggtatcgca accgggcgca gtttgtcctg actgacgaag aacggacgta tctctccgcg
     1981 ccggttaaac cgcgtccaca gctgcaattt agcgagtggc tggcgctgtt taagcatcgg
     2041 acaacctggg ggatgatttt aggtttctct ggcgtcaatt ataccggttg gctctacatc
     2101 gcgtggttac ccggttattt gcaagccgag caaggtttca gtctggcgaa aaccggttgg
     2161 gtggcggcga gtcctttcct cgcggcggca gtcgggatgt gggttaacgg tattgttgtc
     2221 gatcgactgg cgaaaaaagg ctacgacctg gcgaagacgc gtaaaacggc tattgtctgc
     2281 ggtttgatga tgtcggcatt aggcacgttg ctggtcgtgc aatcttcctc gccagcccag
     2341 gcggtagcgt ttatctcaat ggcgctattc tgcgtgcatt tcgctggaac gtctgcatgg
     2401 gggctggtgc aggtgatggt gtcagaaaca aaagtggctt ccatcgccgg gattcaaaac
     2461 tttggcagtt ttgtttttgc ttcctttgct ccgatcgtaa ccggttgggt agtggatacc
     2521 acacactcgt ttaatctggc gttggttatc gcggcctgtg tgacgttcac cggggcgctg
     2581 tgttacttct ttattgtcaa agatcgcatt gagtaatcgt tactatcagg ctctcttgct
     2641 gtgggcctgt agaataaaaa aaagcggatc ctggagatcc gcaaaagttc acgttggctt
     2701 tagttattcg agttgagaaa ctctcgaaac gggcagtgac ttcaagggtt aaaagaggtg
     2761 ccgctccgtt tctgtgagca attatcagtc agaatgcttg atagggataa tcgttcattg
     2821 ctattctacc tatcgccatg aactatcgtg gcgatggagg atggataatg aatattcgtg
     2881 atcttgagta cctggtggca ttggccgagc accgccattt tcggcgtgcg gcagattcct
     2941 gccacgttag ccagccgacg cttagcgggc aaattcgtaa gctggaagat gagttgggcg
     3001 tgatgttgct ggagcggacc agccgtaaag tgttgttcac ccaggcggga atgctgctgg
     3061 tagatcaggc gcgtaccgta ctgcgtgagg tgaaagtcct taaagagatg gcaagccagc
     3121 agggcgagac gatgtccggg ccgctgcaca ttggtttgat tcccacagtt ggaccgtacc
     3181 tgctaccgca tattatccct atgctgcacc agacctttcc aaagctggaa atgtatctgc
     3241 atgaagcaca gacccaccag ttactggcgc aactggacag cggcaaactc gattgcgtga
     3301 tcctcgcgct ggtgaaagag agcgaagcat tcattgaagt gccgttgttt gatgagccaa
     3361 tgttgctggc tatctatgaa gatcacccgt gggcgaaccg cgaatgcgta ccgatggccg
     3421 atctggcagg ggaaaaactg ctgatgctgg aagatggtca ctgtttgcgc gatcaggcaa
     3481 tgggtttctg ttttgaagcc ggggcggatg aagatacaca cttccgcgcg accagcctgg
     3541 agacgctgcg caacatggtg gcggcaggta gcgggatcac tttactgcca gcgctggctg
     3601 tgccgccgga gcgcaaacgc gatggggttg tttatctgcc gtgcattaag ccggaaccac
     3661 gccgcactat tggcctggtt tatcgtcctg gctcaccgct gcgcagccgc tatgagcagc
     3721 tggcagaggc catccgagca agaatggatg gccatttcga taaagtgtta aaacaggcgg
     3781 tttaaaccgt ttaacgcagc tacccgatag gcttccgcca tggtcgggta gttaaaggtg
     3841 gtgttgacga agtactcaat agtgttgccg ccacctttct gttccataat cgcctgaccg
     3901 atatgaataa tttcggcagc gcgctcgcca aagcagtgaa tacccagaat ctcttttgtt
     3961 tcccgatgga acaaaatttt cagcgtgccc acgttcatgc cgacgatttg tgcgcgtgcc
     4021 agatgtttaa actgggcgcg gcccacttca tatggcactt tcatcgcggt cagctgctgt
     4081 tcggttttgc ccacagagct gatttccggg atggtgtaaa tgccggtagg gatatcttca
     4141 atcagatgcg cggtggcttc gccttttacc agcgcctgcg cggcaatgcg cccctggtca
     4201 taggccgctg atgccaggct cggataacca atcacgtcgc ccaccgcgta aacgtgcggc
     4261 tgtgcggtct gatacatgct gttgaccttc agctgtccgc gactgtcagt ttccagccca
     4321 atgttctgta acgccagcga atcggtatta ccggtacgac cgttggcata gagcaggcag
     4381 tcagctttca gttttttacc cgacttcaga tgcatgatca caccgtcgtc acagccttcg
     4441 atcttctcgt actcttcgtt gtgacgaatc actacgccac tgttccagaa gtgataggag
     4501 agagaatctg acatctcttg atcgagaaat gccagcaggc gatcgcgggt gttgatcaga
     4561 tccactttta catccatacc gcggaagatc gacgcatatt cacagccgat cactccagca
     4621 ccatagataa gtacatggcg cggttcgtgg tgcatgctaa gaattgagtc gctgtcgtaa
     4681 atgcgtggat gggtgaaatc aacatctgtt ggatgatatg gacgagagcc gcaggcaata
     4741 acaaattttt cagcggttag tgtttcaacg ctgccgtccg ggcaatccag cgccaacgta
     4801 tgctcgtcaa caaagcgagc gtttccctgc aatatttcac agtgattacg ttcgtaaaat
     4861 ccctgacgca tgcgcgtttg ttgattaatc acgttatcgg catggttaag gatatcggca
     4921 aaagaagagc ggagcagtcg ggaatggtcg ctgtaaagtg ggttttgatt gaattctata
     4981 atgcggctga cggcgtgacg gagagctttc gacgggatgg tgccccagtg ggtgcaaccg
     5041 ccgccaacat tttgataacg ctcgataact gcgacgcgcg caccttgctt aaccaggccc
     5101 attgcagcgc cttcgccgcc ggggccggaa cctattacta tggcatcgta atcgtaggaa
     5161 tgtggcatgg tagggcttac ctgttcttat acataaaagc aacagaatgg taacatttta
     5221 tcgcgggtaa gccaattgat ccccgtcatt tatctggcta tatcctgagc ggcctttgct
     5281 ttgtctgttt cttacttttg ccctgacgtt ttattggatt tttatcgacg atactctccg
     5341 tttaagcggc aggtttccgc tgtacgtaaa agaaccggcc aaagaattgc agtaaatatg
     5401 ttttattgcg ttaccgttca ttcacaatac tggagcaatc cagtatgttc attctctggt
     5461 atagtgccag cagtactttt ggcaaggatt cagacatcgt gatgggcgta agagcgcaac
     5521 aaaaagaaaa aacccgccgt tcgctggtgg aagccgcatt tagccaatta agtgctgaac
     5581 gcagcttcgc cagcctgagt ttgcgtgaag tggcgcgtga agcgggcatt gctcccacct
     5641 ctttttatcg gcatttccgc gacgtagacg aactgggtct gaccatggtt gatgagagcg
     5701 gtttaatgct acgccaactc atgcgccagg cgcgtcagcg tatcgccaaa ggcgggagtg
     5761 tgatccgcac ctcggtctcc acatttatgg agttcatcgg taataatcct aacgccttcc
     5821 ggttattatt gcgggaacgc tccggcacct ccgctgcgtt tcgtgccgcc gttgcgcgtg
     5881 aaattcagca cttcattgcg gaacttgcgg actatctgga actcgaaaac catatgccgc
     5941 gtgcgtttac tgaagcgcaa gccgaagcaa tggtgacaat tgtcttcagt gcgggtgccg
     6001 aggcgttgga cgtcggcgtc gaacaacgtc ggcaattaga agagcgactg gtactgcaac
     6061 tgcgaatgat ttcgaaaggg gcttattact ggtatcgccg tgaacaagag aaaaccgcaa
     6121 ttattccggg aaatgtgaag gacgagtaat gaaacaagca aatcaagata gaggtacgct
     6181 gctgctggcg ttggttgctg gcttatcgat taatggtact ttcgcagcgc tgtttagctc
     6241 cattgtgcca ttttctgtat tcccgattat ttccctggtg ctgacggttt actgcctgca
     6301 tcaacgttat cttaatcgca ccatgccggt aggcttgccg ggtctggcag ctgcctgttt
     6361 tattctcggc gtactgctgt acagcacggt agttcgtgcg gaatatccgg atatcggctc
     6421 taacttcttc ccggcagtac tctccgtcat tatggtgttc tggattggcg cgaagatgcg
     6481 taaccgtaag caggaagttg ctgagtaatc ggtattatgc cggatgctgg cgcatccggc
     6541 atgggtttta cttcgcggtc agtaatacgc cgcactccat atggtgcgtg taggggaact
     6601 gatcaaacag agccagacgt tcgaccttgt gcgtctggct taatgtttcc agattcttgc
     6661 ataacgtttc cggattgcag gagatataca gaatacgtgg atacgcctgc accattttct
     6721 cggtttcact gtccagaccg ctgcgcggtg ggtcgacaaa aatggtttcg cactgataac
     6781 tcttcaagtc tatcccttgc aggcgattaa actcgcgtac accattcatc gcctgagtaa
     6841 attcttctgc cgccatacga ataatttgta cgttatcaat atggttagct gcgatgttgt
     6901 attgcgcagc agcaaccgac ggcttagcga tttcggtggc taatacccga tcaaaattgc
     6961 gcgccagtgc taatgaaaag ttaccgttgc cgcagtacag ctccagtaaa tcgccttttg
     7021 agcctttggt tacgtccagc gcccattcca gcatctgaat attcatcgcc gcgttcggct
     7081 gggtaaaact gttttctacc tgacggtaga tcatctcttt ccctgcgacc ggcagacgtt
     7141 catcgatgta atcttgatcc agctcgattt tggttttcgt tgcccgacca atcagatgca
     7201 cattcagatt ctgcgcgcgc agtgcatcgc gcagggcttc cgcttcctga cgccactcat
     7261 catccagctt tttatggtac aacagggaaa ccaccgcctg attactcagc gtggtgaggt
     7321 aatcaatctg gaacaacttg tggcgcagaa cgggattatt acgcacaccc gcaatcatcg
     7381 ccgtcatcaa ctggttgatg agttcactgg cagcggggaa gctatccacg cggatgcggc
     7441 ttttggtttg ttgatcgaaa atgatgtgat acaggtcatc gccatcgtgc cagatgcgga
     7501 actccgcacg catccggtaa tgactgaccg gcgagcgaaa cacttccgga accaggtcag
     7561 aaaacggtgc catcatactt tgcaaacgta ccactttttc ggctaactgc gcttcatact
     7621 gttctgttgg aaggtgttcg ggggtcatga tgtatcctga aaaattaaag tacgcggcga
     7681 ttgtagggat tgctcatcag atgtccagat cttgatgaat tcctatttgt gagctacgtc
     7741 tggacagtaa cttgttacaa cctgtagcat ccacttgccg gtcctgtgag ttaataggga
     7801 atccagtgcg aatctggagc tgacgcgcag cggtaaggaa aggtgcgatg attgcgttat
     7861 gcggacactg ccatccggtg ggaagtcatc atctcttagt atcttagata cccctccaag
     7921 cccgaagacc tgccggccaa cgtcgcatct ggttctcatc atcgcgtaat attgatgaaa
     7981 cctgcggcat ccttcttcta ttgtggatgc tttacaatga ttaaaaaagc ttcgctgctg
     8041 acggcgtgtt ctgtcacagc cttttccgct tgggcacagg ataccagccc ggatactctc
     8101 gtcgttactg ctaaccgttt tgaacagccg cgcagcactg tgcttgcacc aaccaccgtt
     8161 gtgacccgtc aggatatcga ccgctggcag tcgacctcgg tcaatgatgt gctgcgccgt
     8221 cttccgggcg tcgatatcac ccaaaacggc ggttcaggtc agctctcatc tatttttatt
     8281 cgcggtacaa atgccagtca tgtgttggtg ttaattgatg gcgtacgcct gaatctggcg
     8341 ggggtgagtg gttctgccga ccttagccag ttccctattg cgcttgtcca gcgtgttgaa
     8401 tatatccgtg ggccgcgctc cgctgtttat ggttccgatg caataggcgg ggtggtgaat
     8461 atcatcacga cgcgcgatga acccggaacg gaaatttcag cagggtgggg aagcaatagt
     8521 tatcagaact atgatgtctc tacgcagcaa caactggggg ataagacacg ggtaacgctg
     8581 ttgggcgatt atgcccatac tcatggttat gatgttgttg cctatggtaa taccggaacg
     8641 caagcgcaga cagataacga tggtttttta agtaaaacgc tttatggcgc gctggagcat
     8701 aactttactg atgcctggag cggctttgtg cgcggctatg gctatgataa ccgtaccaat
     8761 tatgacgcgt attattctcc cggttcaccg ttgctcgata cccgtaaact ctatagccaa
     8821 agttgggacg ccgggctgcg ctataacggc gaactgatta aatcacaact cattaccagc
     8881 tatagccata gcaaagatta caactacgat ccccattttg gtcgttatga ttcgtcggcg
     8941 acgctcgatg agatgaagca atacaccgtc cagtgggcaa acaatgtcat cgttggtcac
     9001 ggtagtattg gtgcgggtgt cgactggcag aaacagacta cgacgccggg tacaggttat
     9061 gttgagaatg gatatgatca acgtaatacc ggcatctatc tgaccgggct gcaacaagtc
     9121 ggcgatttta cctttgaagg cgcagcacgc agtgacgata actcacagtt tggtcgtcat
     9181 ggaacctggc aaaccagcgc cggttgggaa ttcatcgaag gttatcgctt cattgcttcc
     9241 tacgggacat cttataaggc accaaatctg gggcaactgt atggcttcta cggaaatccg
     9301 aatctggacc cggagaaaag caaacagtgg gaaggcgcgt ttgaaggctt aaccgctggg
     9361 gtgaactggc gtatttccgg atatcgtaac gatgtcagtg acttgatcga ttatgatgat
     9421 cacaccctga aatattacaa cgaagggaaa gcgcggatta agggcgtcga ggcgaccgcc
     9481 aattttgata ccggaccact gacgcatact gtgagttatg attatgtcga tgcgcgcaat
     9541 gcgattaccg acacgccgtt gttacgccgt gctaaacagc aggtgaaata ccagctcgac
     9601 tggcagttgt atgacttcga ctggggtatt acttatcagt atttaggcac tcgctatgat
     9661 aaggattact catcttatcc ttatcaaacc gttaaaatgg gcggtgtgag cttgtgggat
     9721 cttgcggttg cgtatccggt cacctctcac ctgacagttc gtggtaaaat agccaacctg
     9781 ttcgacaaag attatgagac agtctatggc taccaaactg caggacggga atacaccttg
     9841 tctggcagct acaccttctg aaccacgtcc caccgtgctg gtgtttgact ccggcgtcgg
     9901 tgggttgtcg gtctatgacg agatccggca tctcttaccg gatctccatt acatttatgc
     9961 tttcgataac gtcgcttttc cgtatggcga aaaaagcgaa gagtttattg ttgagcgagt
    10021 ggtggcaatt gtcaccgcag tgcaagaacg ttatcccctt gcgctggctg tggtcgcttg
    10081 caacaccgcc agtaccgttt cacttcctgc attacgcgaa aagttcgact tcccggttgt
    10141 tggtgtcgtg ccggcgatta aacctgctgc acgtctgacg gcaaatggca ttgtcggatt
    10201 actggcaacc cgcggaactg ttaaacgttc ttatactcat gagctgatcg cgcgtttcgc
    10261 taatgaatgc cagatagaaa tgctgggctc ggcagagatg gttgagttgg ctgaagcgaa
    10321 gctacatggc gaagatgttt ctctggatgc actaaaacgt atcctacgcc cgtggttaag
    10381 aatgaaagag ccgccagata ccgttgtatt gggttgcacc catttccctc tactacaaga
    10441 agaactctta caggtgctgc cagagggaac ccggctggtg gattctggcg cagcgattgc
    10501 tcgcagaacg gcctggctgt tagaacatga agctccggat gcaaaatctg ccgatgcgaa
    10561 tattgccttt tgtatggcaa tgacgccaga agctgaacaa ttattgcccg ttttacagcg
    10621 ttacggcttc gaaacgctcg aaaaactggc agttttaggc tgatttggtt gaatgttgcg
    10681 cggtcagaaa attattttaa atttcctctt gtcaggccgg aataactccc tataatgcgc
    10741 caccactgac acggaacaac ggcaaacacg ccgccgggtc agcggggttc tcctgagaac
    10801 tccgacagag aaagcaaaaa taaatgcttg actctgtagc gggaaagcgt attatgcaca
    10861 ccccgcgccg ctgagaaaaa gcgaagcg
//
LOCUS       DAZUDJ010000118        10759 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.119, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000118 DAZUDJ010000000
VERSION     DAZUDJ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10759
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.119"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            80..793
                     /gene="yghS"
                     /locus_tag="ACHY1N_004603"
     CDS             80..793
                     /gene="yghS"
                     /locus_tag="ACHY1N_004603"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006235 - dTTP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFS4046782.1"
                     /translation="MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPT
                     EHIYLGQSSGRIGEWISQLPVIGAPCGRYLRSKAAHVHEKPSTPPGNITALVIYLLSC
                     WRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELK
                     LYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGR
                     HPADEILQASLRAIHAALS"
     gene            825..1582
                     /locus_tag="ACHY1N_004604"
                     /pseudo
     CDS             825..1582
                     /locus_tag="ACHY1N_004604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417458.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1628..2977
                     /locus_tag="ACHY1N_004605"
     CDS             1628..2977
                     /locus_tag="ACHY1N_004605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFS4046783.1"
                     /translation="MAGFNIKHWFADGAFRTIIRNSAWLGSSNVVSALLGLLALSCAG
                     KGMTPAMFGVLVIVQSYAKSISDFIKFQTWQLVVQYGTPALTNNNPQQFRNVVSFSFS
                     LDIVSGAVAIVGGIALLPFLSHSLGLDDQSFWLAALYCTLIPSMASSTPTGILRAVDR
                     FDLIAVQQATKPFLRAAGSVVAWYFDFGFAGFVIAWYVSNLVGGTMYWWFAARELRRR
                     NIHNAFKLNLFESARHIKGAWSFVWSTNIAHSIWSARNSCSTVLVGIVLGPAAAGLFK
                     IAMTFFDAAGTPAGLLGKSFYPEVMRLDPRTTRPWLLGVKSGLLAGGIGILVALAVLI
                     VGKPLISLVFGVKYLEAYDLIQVMLGAIVISMLGFPQESLLLMAGKQRAFLVAQTIAS
                     IGYIVLLFMFCHLFGVLGAAFAYFGGQCLDVVLSLIPTLKAFFQRHSLLYNAAGEKS"
     gene            2977..3801
                     /locus_tag="ACHY1N_004606"
     CDS             2977..3801
                     /locus_tag="ACHY1N_004606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046784.1"
                     /translation="MMRKYFPLEASERLFVAIEEDDVVDAQVSLPPTIALSCTTEIIH
                     DNYALCLQFWLNGVNRQELLRLIRKQTKGDELTTDERKQFKYMRARYKHLRFAQRLYL
                     KKHQAGFLFGKTTVFLGRFQDGFRNGKKNIVSYYGNLLRIYLSSPVWSLVNYSLRHSQ
                     LESVSGFIAYRQKQMHTLKEIIAKPRLTGREFHDVRKIISQQVSYYDTLRSLDPENKE
                     ALQISRFLAAINGLMGDKHDDMVADDMENRQSYDAPVALDSDIRQRLELLISRFPL"
     gene            3813..4373
                     /locus_tag="ACHY1N_004607"
     CDS             3813..4373
                     /locus_tag="ACHY1N_004607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HFS4046785.1"
                     /translation="MSSRLIIALIIMLLAPGVQAHNFVTGKTVTPVYIQEGGELLLNS
                     DDEIHYQKWNSTQLAGKVRIIQYIAGRKSAKKKNSLLIKVVEAANFPQDRFQPTTIVN
                     TDDAIFGTGYFVVGKIEKNKRRYPWAQFVIDGNGQGRVAWRLPEQSSTILVLNKAGQI
                     QWAKDGSLTPEEVDHVIALAQKLINE"
     gene            4404..5474
                     /gene="lptF"
                     /locus_tag="ACHY1N_004608"
     CDS             4404..5474
                     /gene="lptF"
                     /locus_tag="ACHY1N_004608"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HFS4046786.1"
                     /translation="MKLVEHYIMRGTRRLVLIIVGFLIFIFASYSAQRYLTEAANGTL
                     ALYVVLDIVFYKVLIALEMLLPVGLYVSVGVTLGQMYTDSEITAISAAGGSPGRLYKA
                     VLYLAIPLSIFVTLLSMYGRPWAYAQIYQLEQQSQSELDVRQLRAKKFNTNDNGRMIL
                     SQTVDQDNNRLTDALIYTSTANRTRIFRARSVDVVDPSPEKPTVMLHNGTAYLLDHQG
                     RDDNEQIYRNLQLHLNPLDQSPNVKRKAKSVTELARSVFPADHAELQWRQSRGLTALL
                     MALLAISLSRVKPRQGRFSTLLPLTLLFIAIFYGGDVCRTLVANGAIPLIPGLWLVPG
                     LMLMGLLMLVARDFSLLQKFSR"
     gene            5471..6550
                     /gene="lptG"
                     /locus_tag="ACHY1N_004609"
     CDS             5471..6550
                     /gene="lptG"
                     /locus_tag="ACHY1N_004609"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HFS4046787.1"
                     /translation="MNVFSRYLIRHLFLGFAAAAGLLLPLFTTFNLINELDDVSPGGY
                     RWTQAVLVVLMTLPRTLVELSPFIALLGGIVGLGQLSKNSELTAIRSTGFSIFRIALV
                     ALVAGILWTVSLGAIDEWVASPLQQQALQIKSTATALGEDDDITGNMLWARRGNEFVT
                     VKSLNEQGQPVGVEIFHYRDDLSLESYIYARSATIEDDKTWILHGVNHKKWLNGKETL
                     ETSDNLAWQSAFTSMDLDELSMPGNTFSVRQLNHYIHYLQETGQPSSEYRLALWEKLG
                     QPILTLAMILLAVPFTFSAPRSPGMGSRLAVGVIVGLLTWISYQIMVNLGLLFALSAP
                     VTALGLPVAFVLVALSLVYWYDRQH"
     gene            complement(6586..7758)
                     /locus_tag="ACHY1N_004610"
     CDS             complement(6586..7758)
                     /locus_tag="ACHY1N_004610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFS4046788.1"
                     /translation="MGLYDKYARLAGERLQFNDNGLTPFGTCIDEVYSATEGRIGNKK
                     VILAGTNNYLGLTFNHDAISEGQAALAAQGTGTTGSRMANGSYAPHLALEKEIAEFFN
                     RPTAIVFSTGYTANLGVISALADHNAVVLLDADSHASIYDACSLGGAEIIRFRHNDAK
                     DLERRMVRLGERAKEAIIIVEGIYSMLGDVAPLAEIVDIKRRLGGYLIVDEAHSFGVL
                     GATGRGLAEAVGVEDDVDIIVGTFSKSLASIGGFAVGSEAMEVLRYGSRPYIFTASPS
                     PSCIATVRSSLRTIATQPELRQKLMDNANHLYDGLQKLGYELSSHISPVVPVIIGSKE
                     EGLRIWRELISLGVYVNLILPPAAPAGITLLRCSVNAAHSREQIDAIIQAFATLKQ"
     gene            complement(7758..8006)
                     /locus_tag="ACHY1N_004611"
     CDS             complement(7758..8006)
                     /locus_tag="ACHY1N_004611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFS4046789.1"
                     /translation="MVNREIVMDYILSCLQDLVENGVEIKPDSDLVNDLGLESIKVMD
                     LLMMLEDRFDISIPINILLDVKTPAQLMETLLPWLENK"
     gene            complement(8038..8952)
                     /locus_tag="ACHY1N_004612"
     CDS             complement(8038..8952)
                     /locus_tag="ACHY1N_004612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001481799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFS4046790.1"
                     /translation="MNQTVAVTGATGFIGKYIIDNLLARGFHVRALTRTARAHVNDNL
                     TWVRGSLEDTHSLSKLVAGASAVVHCAGQVRGHKEEIFTRCNVDGSLRLMQAAKESGF
                     CQRFLFISSLAARHPELSWYANSKHVAEQRLTAMADEITLGVFRPTAVYGPGDKELKP
                     LFDWMLRGLLPRLGAPDTQLSFLHVTDFAQAVGQWLSAETIQTQTYELCDGVAGGYDW
                     QRIQQLAANVRCGSVRMVGIPLPVLTCLADISTALSRLAGKEPMLTRSKIRELTHADW
                     SASNNRISEDINWFPGISLEHALRNGLF"
     gene            complement(8949..10670)
                     /locus_tag="ACHY1N_004613"
     CDS             complement(8949..10670)
                     /locus_tag="ACHY1N_004613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acyl-AMP ligase"
                     /protein_id="HFS4046791.1"
                     /translation="MSNKIFTHSLPMRYADFPTLVDALDYAALSSAGMNFYDRRCQLE
                     DQLEYQTLKTRAEAGAKRLLSLNLKKGERVALIAETSSGFVEAFFACQYAGLVAVPLA
                     IPMGVGQRDSWSAKLQGLLASCQPAAIITGDEWLPLVNAATHNNPELHVLSHAWFKAL
                     PEADVALQRPVPNDIAYLQYTSGSTRFPRGVIITHREVMANLRAISHDGIKLRPGDRC
                     VSWLPFYHDMGLVGFLLTPVATQLSVDYLRTQDFAMRPLQWLKLISKNRGTVSVAPPF
                     GYELCQRRVNEKDLAELDLSCWRVAGIGAEPISAEQLHQFAECFRQVNFDDKTFMPCY
                     GLAENALAVSFSDEGSGVVVNEVDRDILEYQGKAVAPGAETRAVSTFVNCGKALPEHG
                     IEIRNEAGMPVAERVVGHICISGPSLMSGYFGDQVSQDEIAATGWLDTGDLGYLLDGY
                     LYVTGRIKDLIIIRGRNIWPQDIEYIAEQEPEIHSGDAIAFVTAQEKIILQIQCRISD
                     EERRGQLIHALAARIQSEFGVTAAIDLLPPHSIPRTSSGKPARAEAKKRYQKAYAASL
                     HVQESLA"
BASE COUNT         2591 a         2675 c         2821 g         2672 t
ORIGIN      
        1 attgtcacaa taaggttgaa aggatattct gagcacggac cacgtaatat tcaatacatt
       61 atttactgcc gggtttttcg tgaatcaacg taatatgtca ataattaatt ccacgccagt
      121 gcgtgttatt gccattgtag gatgtgatgg ttcaggtaaa tcgaccctca cggcaagcct
      181 ggtaaatgaa ctggcagcaa gaatgccaac agaacacatt tatctcgggc aatcgtccgg
      241 gcgaattggc gaatggattt cacagctccc tgttattggc gcaccttgtg ggcgttatct
      301 gcgaagtaaa gcggcacatg tgcacgaaaa accctcaaca ccgcctggca atattactgc
      361 gctggttatc tatctgcttt cctgctggcg ggcgtacaag tttcgcaaaa tgttgtgtaa
      421 aagccagcaa ggctttctgc tcatcaccga ccgctacccg caggttgaag tgccgggttt
      481 tcgctttgat ggcccgcaat tggcaaaaac cacgggcggt aacggttgga taaaaatgtt
      541 aaggcagcgc gagctgaagc tgtaccaatg gatggcatct tatttgcccg tattgttgat
      601 tcgtcttggc attgatgaac aaaccgcgtt tgcgcgtaaa cctgaccacc aactggcagc
      661 gttacaggaa aaaatcgccg ttacgccgca actgacattc aatggcgcaa agatccttga
      721 actggatggg cgacaccccg ccgatgaaat tctgcaagcg tcactacgcg caattcacgc
      781 cgcgctttcc tgatcaccaa aatggatagg ggatgattta acgaatggat gcactacaaa
      841 ctcaaactgt taatagtaca accgcgccgc agcccaacta cattccgggg ctgattgcgg
      901 tggtcgggtg tgatggcacc ggtaaatcca cactgaccac cgacctggtg aaatcgctgc
      961 aacaacactg gcaaaccgag cggcgctatc tggggctgct ctccggcgaa gacggcgaca
     1021 aaatcaaacg attgccgttg gttggcgtct ggctggaacg gcgactggcg gccaaatcct
     1081 cgaaaaccca aagcatgaaa accaaatctc cggcgctatg ggcggcggtg attatgtact
     1141 gcttctcgct gcgaagaatg gcgaatctac gcaaggttca gcgactggcg caaagtggcg
     1201 ttctggtggt cagcgatcgc ttcccgcagg ctgaaatttc gggcttttat tatgatggac
     1261 cggggattgg cgtcgaacgt gcgaccggga aaatcagcat gtttctggcg cagcgcgaac
     1321 ggcgtttata ccaacaaatg gcgcaatatc gcccggaatt aattattcgc ctgggcattg
     1381 atattgagac tgccatctcc cgcaagcctg accatgacta tgccgagctg caggacaaat
     1441 cggcgtcatg tcgacgattg gctataacgg cacaaaaatt cttgagattg attccagagc
     1501 gccctacagc gaagtgctgg aacaggcaca gaaggcggtt tctctggttg ccatcgtttc
     1561 tgaccgccga agtttaactt aaggctggcg ggatactttt tactatcaac gataaggtca
     1621 ggctgaattg gcgggtttta acatcaaaca ttggtttgca gatggcgcgt ttcgcaccat
     1681 tattcgcaat agcgcctggt taggctccag taatgtcgtg agcgccttgc tgggtctgtt
     1741 ggcgctctcg tgtgccggta aagggatgac gcccgccatg tttggcgtac tggtgattgt
     1801 gcaatcgtac gccaagtcga tcagcgattt tattaagttt cagacatggc aactggtggt
     1861 tcagtacgga acgccagcct tgaccaacaa taatccgcag caatttcgca atgtcgtctc
     1921 attttccttc tcgctggata tcgtcagcgg cgcggtggcg attgtcggtg gcattgcctt
     1981 actgccattc ctttcccatt cattaggtct ggatgaccaa agcttttggc tggcggcgct
     2041 ctattgcacg ctcattcctt caatggcttc ctccacgccg accggcattc tgcgtgcggt
     2101 agatcgcttc gatttaattg ctgtacagca ggcgacgaaa ccttttctgc gcgcagcggg
     2161 gagcgtcgta gcctggtatt ttgactttgg ttttgcgggt tttgttattg cctggtacgt
     2221 gtcgaatctg gttggcggca ccatgtactg gtggtttgca gcgcgcgaat tacgccgcag
     2281 aaatatccat aatgccttca aattgaatct gtttgagtct gcccgacaca tcaaaggcgc
     2341 gtggagtttt gtctggtcaa ccaacattgc ccactccatc tggtcggcgc gtaactcgtg
     2401 cagcacagtg ctggtgggga tcgtgttagg acccgctgcc gccgggttat ttaaaatcgc
     2461 catgacattc ttcgacgccg ccggaacgcc agcgggtttg ctgggtaaaa gtttttaccc
     2521 agaggtgatg cgtttagatc cgcgcaccac cagaccgtgg ttgttaggtg tgaagtccgg
     2581 tttactggcg ggcggaatcg gtattctggt ggcgctcgcg gtgttgatcg tcggcaagcc
     2641 gctcatttcg cttgtgtttg gcgttaagta tctcgaagcg tatgacctga ttcaggtgat
     2701 gctgggcgca attgtgattt cgatgctggg tttcccgcag gagtcattgc tattgatggc
     2761 gggaaaacag cgcgcttttc tcgtggcgca aaccatcgcc tcaatcggct acatcgtatt
     2821 gctgttcatg ttctgtcatc tgtttggtgt gctgggagca gcgtttgctt acttcggtgg
     2881 gcaatgtctg gatgtggtgc tctcgttaat tccaacttta aaggcatttt ttcagcgtca
     2941 ttccttgctt tataacgcag ccggagagaa atcctgatga tgagaaaata tttcccgctt
     3001 gaggcgagcg agcgtctatt tgttgcgatt gaggaagatg atgtcgttga tgcccaggtc
     3061 agtttgccgc cgactattgc actaagttgt accaccgaaa tcatccatga taattacgcg
     3121 ttatgcctgc agttctggct caatggcgtt aatcgtcagg agttactgcg tttaattcgc
     3181 aaacagacca aaggcgatga gctgacgaca gacgagcgca aacagtttaa atacatgcga
     3241 gcgcgctaca agcacctgcg ttttgcgcaa cggctgtatt taaagaagca tcaggccgga
     3301 tttttattcg gcaaaacgac cgtttttctg gggcgttttc aggacggctt tcgtaacggt
     3361 aagaaaaata ttgtgtcgta ttacggcaac ctgttacgga tttatttaag ctctccggtc
     3421 tggtcgttgg tgaactattc attacgccat agccagttag aaagcgtaag cggttttatt
     3481 gcctatcggc aaaagcaaat gcataccctg aaagagatta ttgccaaacc gcgactaacc
     3541 ggtagggaat ttcatgatgt gcgaaaaatc atcagccagc aggtttctta ttacgacacc
     3601 ttaagatcgc ttgatcctga aaataaagag gcgttacaga tatcccgctt cctcgccgcc
     3661 attaatggcc tgatgggaga taaacacgac gacatggtgg cggatgatat ggaaaaccgc
     3721 cagtcgtatg atgcaccggt ggcgctggat agcgatattc gccagcgctt agagctgctg
     3781 atttcgcgtt ttccgctata accggagcaa tgatgtcatc tcgtttgatt attgcgctga
     3841 ttatcatgct gttagccccg ggtgtgcagg cacacaattt cgtcactggc aaaacggtta
     3901 cccctgttta tatccaggaa ggcggcgagc tgcttctgaa tagcgacgac gaaattcact
     3961 accaaaagtg gaacagcaca caattggcgg gaaaagtccg cattatccag tatatcgccg
     4021 ggcgtaagtc ggcgaagaaa aagaactcac tgttaattaa agtggttgaa gcggcaaact
     4081 ttccgcagga tcgttttcag cccaccacca ttgtgaacac cgatgatgcc atctttggta
     4141 ctggctattt tgttgttggc aaaatcgaaa aaaataaacg ccgctatccg tgggcgcaat
     4201 tcgttattga cggcaatgga cagggacgcg ttgcctggcg cttgccggag cagagttcaa
     4261 ccattctggt gctgaataaa gccgggcaaa ttcagtgggc aaaggacggc agcctgacgc
     4321 cggaagaggt agatcatgtc attgcgttgg cgcagaaact gatcaatgaa taaaaaactc
     4381 aaaggattga gggcgttagt gagatgaagc tggttgaaca ctacatcatg cgtggtacgc
     4441 gccgtctggt gctgattatc gtcggttttc tgatctttat tttcgccagc tactccgcac
     4501 agcgttatct gaccgaagcg gcaaatggga cattagctct ttatgttgtg ctggatatcg
     4561 ttttctacaa agtactgatt gcactggaga tgttgttacc tgttggtctg tatgtgtcag
     4621 ttggcgtgac gctagggcag atgtataccg actcggaaat taccgctatc tctgcggcgg
     4681 ggggcagtcc gggacgcttg tacaaagccg ttctttatct ggcgataccg ctaagtattt
     4741 ttgtcaccct tctgtcgatg tatggtcgtc cgtgggctta tgcgcagatt tatcaactgg
     4801 agcaacagtc gcagtcggag ctggatgttc gccagttgcg ggcaaagaaa tttaacacta
     4861 acgataacgg acgaatgatc ctttcgcaga cggttgatca ggataataat cgcctgactg
     4921 acgcgctgat ttatacttct actgccaatc gaacccgtat tttccgcgcc cgttcggttg
     4981 atgtggttga cccatcaccc gagaaaccga ccgttatgtt gcacaacggc actgcctatc
     5041 ttctcgatca tcaagggcgt gacgacaacg aacagatcta ccgtaatctg caattacatc
     5101 tgaatccgct ggatcaaagc ccgaacgtca aacgcaaagc gaaatcggtc acggagctgg
     5161 cgcgctccgt ctttcctgcc gatcatgccg aactgcaatg gcgacaaagc cgtggtctga
     5221 cagcattgtt gatggcgctg ctggccattt cattaagtcg ggtaaaaccg cggcaagggc
     5281 gattttcaac gttattgcca ctgacgttgc tgtttattgc cattttttat ggcggcgacg
     5341 tctgccgtac gctggtggct aacggcgcga ttcccctcat tcctggtttg tggttagtgc
     5401 ccggactcat gctaatgggc ctgctgatgc tggtcgcacg cgacttctct ttgctgcaga
     5461 aattttcccg atgaatgttt tcagtcgcta tttaatccgt catctctttc tcggttttgc
     5521 cgccgccgca gggctattgc tgccgctttt taccaccttc aacttgatta acgaactgga
     5581 tgatgtcagc ccgggcggtt atcgctggac tcaggcggtg ctggtggtgc taatgacctt
     5641 accgcgcaca ctggtcgaac tttcgccgtt tatcgcgtta ttgggtggta ttgttggact
     5701 ggggcagtta tcgaaaaaca gtgagcttac cgccattcgc agcacggggt tttctatctt
     5761 ccgtattgca ctggtggcgc tggttgccgg gatattgtgg actgtttcgt taggcgcgat
     5821 agatgagtgg gtggcgtcgc cattgcagca acaggcgttg caaatcaaat cgaccgccac
     5881 cgcgttgggg gaggacgatg acattaccgg caatatgctg tgggccaggc gcggtaatga
     5941 atttgtgacg gtgaaatcgc tgaacgagca gggccagccg gtgggcgtgg agatatttca
     6001 ttatcgcgac gatctctcgc tcgaatctta catttatgca cgcagtgcca ccattgaaga
     6061 cgacaaaacg tggatcctgc atggtgtgaa tcataaaaaa tggcttaacg gtaaagaaac
     6121 gctggaaaca tcagataatc ttgcctggca atcggccttc accagtatgg atcttgatga
     6181 gttatcgatg ccggggaata ctttttctgt ccgtcagctt aatcattaca tccattattt
     6241 gcaggaaacc gggcaaccca gcagcgaata ccgccttgca ctgtgggaaa aactggggca
     6301 accgatcctg accctggcga tgattttgct ggctgtaccg tttaccttta gcgccccgcg
     6361 ctcgccaggg atgggtagcc gtctcgctgt aggcgtcatc gtgggcttac tcacctggat
     6421 cagctatcaa atcatggtta atctgggatt gctatttgcg ttaagcgcac ctgttaccgc
     6481 gctcggttta ccggtagcgt ttgtgttggt ggcgttgagc ctggtgtatt ggtatgacag
     6541 acaacattaa acccgccgtg gcgcaaacac cacggcgggc tcacattact gcttcagagt
     6601 agcaaatgcc tgaatgatgg catcgatttg ctcacgactg tgggcagcat ttacgctaca
     6661 gcgcagcagc gtgatgcctg caggcgcggc aggcggcagg ataagattca catacacgcc
     6721 cagcgagata agctcgcgcc agatgcgtaa accttcctct ttcgaaccga ttattactgg
     6781 cactaccggg ctaatatgtg aacttaactc ataacccagt ttttgcagac cgtcatacag
     6841 atggttggcg ttatccatca gcttttgccg cagctctggt tgtgtggcaa tagttcttaa
     6901 cgacgagcgc acggtcgcaa tgcaggacgg agaaggagag gcggtaaaaa tatacgggcg
     6961 gctgccgtag cgcagcactt ccatcgcttc cgaaccgaca gcaaaaccgc caatcgaggc
     7021 cagactttta ctgaaagtac caacgataat atccacatca tcttcaacgc cgacagcttc
     7081 agccagtccg cgccccgttg cgcctaacac gccaaacgaa tgcgcttcat cgacaatcaa
     7141 ataaccaccg agacgacgtt tgatatcaac aatttccgcc agcggcgcaa cgtcaccgag
     7201 catgctgtag atgccctcaa cgatgataat cgcctctttc gcccgttcac cgaggcgaac
     7261 catgcgccgt tccagatctt tagcatcgtt atggcggaaa cgaataattt ccgcgccacc
     7321 gagagaacag gcgtcataaa tactggcgtg gctgtcggca tccagtaaca ccacggcgtt
     7381 atggtcggca agtgcgctga tgacgcctaa attagcggta taaccggttg aaaaaacgat
     7441 agcggtaggg cgattgaaaa actcggcaat ctctttctct aacgccaggt gcggcgcata
     7501 actgccgttt gccatacgag aaccggtggt gccggtgcct tgggccgcta acgctgcctg
     7561 accttcgctg atggcatcat gattaaaggt taaaccgaga taattattgg tcccggccag
     7621 aatcactttt ttattgccga tccggccttc ggtggcggaa tacacttcat caatacaggt
     7681 gccaaacggt gttaacccgt tgtcattaaa ttgcagtcgc tcgccagcaa ggcgcgcata
     7741 tttatcgtat agccccatta tttattctcc agccatggaa gtagagtttc cattaattgc
     7801 gcaggggttt tgacatccag cagaatatta ataggaatgg aaatatcgaa tctgtcttcc
     7861 agcatcatta agagatccat cactttgatc gactccaggc caagatcgtt gacgagatcg
     7921 ctgtcgggct taatttccac accgttttcg accaaatcct gtaaacagga aaggatgtaa
     7981 tccattacta tttcacgatt taccatagaa acgttaacac acctttaaac aagacaatca
     8041 aaatagcccg ttgcgtaatg cgtgttccag gctaatcccg ggaaaccaat taatatcttc
     8101 agaaatacgg ttattacttg ccgaccagtc ggcgtgggtt aattcacgaa ttttcgagcg
     8161 ggtcagcata ggttctttac ctgccaggcg actcaacgcg gtactgatat ccgcaaggca
     8221 ggtgagtacc ggcagaggaa taccaaccat tcgcacggaa ccgcaacgga cgttggcggc
     8281 aagttgctgt atgcgttgcc agtcatagcc gccagcgacg ccatcgcata attcataggt
     8341 ttgcgtctgt atagtttcgg cgcttaacca ctgacccact gcttgcgcga aatcggtgac
     8401 gtgcagaaaa gagagctgtg tatctggcgc accaagtcgt ggcagcaggc cgcgcagcat
     8461 ccagtcaaac agcggtttta actctttatc gccgggacca tatacggctg tcgggcgaaa
     8521 aacgcccagc gtaatttcgt cagccattgc agtcagccgt tgttcggcga cgtgtttgga
     8581 atttgcgtac caggagagtt cgggatggcg cgccgccagc gaagagataa acagaaaacg
     8641 ttggcaaaaa ccgctctctt ttgctgcttg catcaggcgc aggctgccgt caacgttaca
     8701 gcgggtgaaa atctcttctt tgtgcccgcg cacttgcccg gcgcaatgga ccaccgcgct
     8761 ggctccggca accagcttgc taagtgaatg agtatcttcc agcgaaccgc gcacccaggt
     8821 gagattatca ttgacgtgag cgcgggcagt acgcgtcaat gcgcgaacgt gaaagccgcg
     8881 ggcgagcagg ttatcgataa tatatttacc gataaacccg gtagcgcccg tcaccgcgac
     8941 agtttgattc atgccaggga ttcctgcaca tgaaggcttg cagcataagc cttctgataa
     9001 cgttttttcg cttccgcacg ggcaggcttg ccggaggatg ttcggggaat actgtggggc
     9061 ggcaacagat cgatagccgc tgttacgcca aattcgcttt ggatccgtgc tgccagcgcg
     9121 tggataagct gcccgcgacg ttcttcgtcg ctgatccgac actggatctg caaaatgatt
     9181 ttttcctggg cggtaacaaa agcaatcgca tcgccagaat gaatttccgg ttcttgttcc
     9241 gcaatatatt caatatcctg cggccagata ttacggccac gaataataat cagatcttta
     9301 atacgtccgg tgacatacag ataaccgtcc agcagataac cgaggtcgcc ggtgtctaac
     9361 cagcccgtcg cggcaatctc gtcttgcgaa acctggtcgc caaagtaacc gctcatcagg
     9421 ctggggccgg agatgcaaat atggcctacc acacgttccg cgaccggcat acctgcttca
     9481 ttgcggattt caatgccatg ttccggcaac gctttgccgc agttgacgaa agtcgatacg
     9541 gcgcgtgttt cagcacccgg cgcgacggct ttgccctgat attctaggat gtcgcgatcc
     9601 acttcgttaa ccacaacccc agagccttca tcagagaagc tgacagccag cgcattttct
     9661 gccagtccgt agcacggcat gaacgtttta tcgtcaaagt taacctgacg gaaacattca
     9721 gcgaattgat ggagttgttc tgcggagatc ggctcagcac caataccagc gacgcgccag
     9781 caggaaagat ccagttcagc gagatctttt tcattcacgc ggcgctggca caattcatag
     9841 ccaaacggcg gcgcaacgga aacggtgccg cgatttttac tgatcaattt aagccattgc
     9901 agaggacgca tggcaaaatc ctgagtgcgc aaataatcta ctgaaagttg cgtggcgacg
     9961 ggggtcagga gaaagccgac cagtcccata tcatggtaga aaggcagcca ggagacgcag
    10021 cggtcgccag ggcgtaattt aatgccatcg tggcttatag cacgtagatt agccatcact
    10081 tcgcgatggg tgataatgac gccacgggga aaacgggtgc tgccggaggt gtactggagg
    10141 taggcgatat cgttcggaac tggacgctgg agcgcaacat cggcttccgg taatgcctta
    10201 aaccaggcgt ggcttaaaac atgtaattcg gggttgttat gcgtcgcggc attgaccagt
    10261 ggcaaccact catcaccagt gataatggct gcgggctggc aacttgccag taaaccctgg
    10321 agtttggcgc tccaggaatc ccgctgaccg acgcccattg gaatcgccaa cgggacggcg
    10381 actaagccag catactgaca ggcaaaaaaa gcctctacaa acccgctact cgtttcggca
    10441 atcagcgcca cgcgttcgcc ttttttcagg ttcagcgata acaaccgctt cgcaccagct
    10501 tcggcacgcg tttttaacgt ctgatattcc agttgatctt caagttggca acgtctgtca
    10561 taaaaattca ttccggcgct actcagagcg gcgtagtcca aagcatcaac cagcgttgga
    10621 aaatcggcat agcgcatagg tagggaatgc gtaaagattt tattagacat atacaccacg
    10681 aaaaaattgg atatcaaaaa taaaatgaca ataatgcggt ggattatata ggcataaaag
    10741 ataaatgaga tagtatttt
//
LOCUS       DAZUDJ010000119        10720 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.120, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000119 DAZUDJ010000000
VERSION     DAZUDJ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10720
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.120"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..566
                     /gene="nleF"
                     /locus_tag="ACHY1N_004614"
     CDS             <1..566
                     /gene="nleF"
                     /locus_tag="ACHY1N_004614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="T3SS effector caspase inhibitor NleF"
                     /protein_id="HFS4046792.1"
                     /translation="PTSGSSANLYSWMYVSGRGNPSTPESVSELNHNHFLTPELQDKL
                     DAMISIYSNARNSNELEEIYQELSAFVSGLMDKRNSVFEVRNENTDEVVGALREGMTI
                     DDRDGYIRELFFLYSLKVKIEESRQGKEDSKCKVYGLLCPHHSSELYGDLRAMKCLVE
                     GCSDDFDPFDIIRVPDLTYNKGALQCG"
     gene            complement(982..1070)
                     /locus_tag="ACHY1N_004615"
                     /pseudo
     CDS             complement(982..1070)
                     /locus_tag="ACHY1N_004615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            complement(1911..2441)
                     /gene="yodB"
                     /locus_tag="ACHY1N_004616"
     CDS             complement(1911..2441)
                     /gene="yodB"
                     /locus_tag="ACHY1N_004616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416483.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HFS4046793.1"
                     /translation="MNRFSKTQIYLHWITLLFVAITYAAMELRGWFPKGSSTYLLMRE
                     THYNAGIFVWVLMFSRLIIKHRYSDPSIVPPPPAWQMKAASLMHIMLYITFLALPLLG
                     IALMAYSGKSWSFLGFNVSPFVTPNSEIKALIKNIHETWANIGYFLIAAHAGAALFHH
                     YIQKDNTLLRMMPRRK"
     gene            complement(2784..3434)
                     /gene="zinT"
                     /locus_tag="ACHY1N_004617"
     CDS             complement(2784..3434)
                     /gene="zinT"
                     /locus_tag="ACHY1N_004617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HFS4046794.1"
                     /translation="MAIRLHKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGV
                     FDDANVQNRTLSDWDGVWQSVYPLLQSGKLDPVFQKKADADKTKTFAEIKDYYHKGYA
                     TDIEMIGIEDGIVEFHRNNETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPK
                     YIQFSDHIIAPRKSSHFHIFMGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH"
     gene            complement(3691..4326)
                     /gene="msrQ"
                     /locus_tag="ACHY1N_004618"
     CDS             complement(3691..4326)
                     /gene="msrQ"
                     /locus_tag="ACHY1N_004618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HFS4046795.1"
                     /translation="MRLTAKQVTWLKVSLHLAGLLPFLWLVWAINHGGLGADPVKDIQ
                     HFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGV
                     NNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAIL
                     APIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLRSLFNRLRKQVHNKLSV"
     gene            complement(4327..5331)
                     /gene="msrP"
                     /locus_tag="ACHY1N_004619"
     CDS             complement(4327..5331)
                     /gene="msrP"
                     /locus_tag="ACHY1N_004619"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016667 - oxidoreductase activity, acting
                     on a sulfur group of donors [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HFS4046796.1"
                     /translation="MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHA
                     DLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPVDKVSGYNNFYEFGLDKADPAA
                     NAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
                     "
     gene            complement(5440..5853)
                     /gene="hiuH"
                     /locus_tag="ACHY1N_004620"
     CDS             complement(5440..5853)
                     /gene="hiuH"
                     /locus_tag="ACHY1N_004620"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HFS4046797.1"
                     /translation="MLKRYLVLSVVTAAFSLPSLVYAAQQNILSVHILNQQTGKPAAD
                     VTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLES
                     FFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS"
     gene            5986..6657
                     /gene="hprR"
                     /locus_tag="ACHY1N_004621"
     CDS             5986..6657
                     /gene="hprR"
                     /locus_tag="ACHY1N_004621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HFS4046798.1"
                     /translation="MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDD
                     YALIILDIMLPGMDGWQILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPF
                     SFSELLARVRAQLRQHHALNSTLEISGLRMDSVSQSVSRDNISITLTRKEFQLLWLLA
                     SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSF
                     VAVKK"
     gene            6657..8015
                     /gene="hprS"
                     /locus_tag="ACHY1N_004622"
     CDS             6657..8015
                     /gene="hprS"
                     /locus_tag="ACHY1N_004622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HprS"
                     /protein_id="HFS4046799.1"
                     /translation="MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTT
                     LINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDILIIHGDSINKIVNRTNVSDDMLN
                     NIPASETISAAGIYRSIINDTEVDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
                     SIIICIVAIVLCSVLSPLLIRTGLREIKKLSGVTEALNYNDSREPVEVSALPRELKPL
                     GQALNKMHQALVKDFERLSQFADDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIA
                     GNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICF
                     KVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSHIHITSFLDTNGYLNIDVASPGTK
                     IHEPEKLFRRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLNKHNVFRITLPQ
                     RN"
     gene            complement(8122..8973)
                     /gene="hchA"
                     /locus_tag="ACHY1N_004623"
     CDS             complement(8122..8973)
                     /gene="hchA"
                     /locus_tag="ACHY1N_004623"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036524 - protein deglycase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase III HchA"
                     /protein_id="HFS4046800.1"
                     /translation="MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKP
                     YRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMT
                     KFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIG
                     LPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTP
                     EIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQE
                     MLAAYAG"
     gene            complement(9566..10639)
                     /locus_tag="ACHY1N_004624"
     CDS             complement(9566..10639)
                     /locus_tag="ACHY1N_004624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HFS4046801.1"
                     /translation="MKRKVLAMLVPALLVAGAANAAEIYNKDGNKVDFYGKMVGERIW
                     SNTDDNNSENEDTSYARFGVKGETQITSELTGFGQFEYNLDASKPEGSNQEKTRLTFA
                     GLKYNELGSFDYGRNYGVAYDAAAYTDMLVEWGGDSWASADNFMNGRTNGVATYRNSD
                     FFGLVDGLNFAVQYQGKNSNRGVTKQNGDGYALSVDYNIEGFGFVGAYSKSDRTNEQA
                     GDGYGDNAEVWSLAAKYDANNIYAAMMYGETRNMTVLANDHFANKTQNFEAVVQYQFD
                     FGLRPSLGYVYSKGKDLYARNGHKGVDADRVNYIEVGTWYYFNKNMNVYTAYKFNLLD
                     KDDAAITDAATDDQFAVGIVYQF"
BASE COUNT         3015 a         2169 c         2444 g         3092 t
ORIGIN      
        1 taccaacaag tggctcttca gcaaatcttt attcatggat gtatgtatca ggaagaggta
       61 acccttcgac tccggaatca gtaagtgaac ttaatcataa tcattttctt actcctgaat
      121 tacaagataa acttgatgct atgatctcta tatactcaaa tgccagaaat agtaatgagc
      181 ttgaggaaat ttatcaagag ctaagtgctt ttgtaagtgg gctgatggat aagagaaata
      241 gtgtatttga ggtgagaaat gaaaatactg atgaggttgt cggagcactg agggagggga
      301 tgacgataga tgacagggat ggttatatca gggagctttt ttttctgtat tcattgaaag
      361 taaaaattga ggaaagtaga caaggtaaag aagattctaa atgtaaagtt tatggtctgt
      421 tatgtccgca tcactcttca gagctatatg gtgatctacg agcaatgaaa tgtcttgtgg
      481 aaggatgcag tgatgatttt gatccttttg atattattag ggtgccggat cttacttaca
      541 acaaaggagc tttacaatgt ggatgattag agggaggtcc tgtgagcctg cttatcattt
      601 tgtgtaaacg ctttttttaa aagtgaccat caaggtggct accaagctcg attataaagt
      661 agcattgtcc atttctgtga tgtggattgc cagccaatca ctttgtttgc tgacttgtag
      721 tcggggatat cgggggcacc ttgcatttcc tgacggcgtg ctatacgaca cctcactgta
      781 cacacgtagt tacaaattta ccccagcgca atggtctcag gagaggggcg attaatttca
      841 tcagatattc ttcgtcagaa ggtggtgatt atccatgata tttgtgtatc gactttttat
      901 aagaggtttc tggtcgggat tatataaaac tgcggacacg tcgtatgcaa gaaggcgcta
      961 cggttttctg ataaaccttt cgccagcatc atctgcttca gcccagtaaa aagagacgcg
     1021 aaaaatgcac aacaggcacc acacgtcatg catggattag gattgctcat aaattcacta
     1081 cttgagtatc agtaatgtta agggatatca ggaaatattt tatgagaaag aaaaacagca
     1141 aactggtcaa aaataactca aagaaggctt ggaatattct tattgaattc aacgtagttt
     1201 attgattttt cgtgtatgtt tttaagacat ttattccaag aaaaatttat aaccttttga
     1261 ttttgcgatt cggtatcatc ggtctcgaaa accggagtag gggcaactct accgggggtt
     1321 caaatccccc tctctccgcc actttatcaa tgacttatct cccgacttcc cgccttgctt
     1381 ttcctaaaca gaacaatcgt agaatattct tgaagggtta gatcgtcact gttttctgtt
     1441 cgatactgtg acattcagca cttgattcgc tatggatctg acaggaagct ttcgagcgaa
     1501 aatgtgcagt tattcagtcg ttttcttatc gctcaccatt attcttttag acattcatcc
     1561 tatgaaactg ccgcaaagtt ggtggtggga actgaagttg cgtagagaag gggtcaataa
     1621 ttgagtcaaa aaagtaacgc ggccgtcaga ttaaagccgc gggacaaagt ccataatttc
     1681 caagagttgt tgaatttccc agcttttttg aaagcctttg tatcatacta acaagtaaaa
     1741 aaggtttaaa taccaaaatt aacctgtatt tttgataagt cttaccattg tacgatttac
     1801 acagtttctg ctcctccttg ttgatagtgg aaagggtgca ttgtgcactt gcgtaaacat
     1861 ttatgacgcg ttgatgtcca tggttcacat ttccttgtca ggggatcgac ttatttgcgg
     1921 cgaggcatca ttcgtaacag agtattatct ttctgaatgt agtgatgaaa gagtgctgcg
     1981 ccagcgtgag ctgcgattaa aaagtaacct atatttgccc aggtttcgtg aatatttttt
     2041 atcagtgctt taatttcgct gtttggggta acaaagggag acacattgaa accaaggaaa
     2101 ctccacgatt ttccactgta agccatcaaa gcaatcccca gcagaggaag tgcaaggaag
     2161 gttatataaa gcatgatgtg cattagcgaa gccgctttca tttgccaggc aggtggcggt
     2221 ggcacaatag aaggatcact ataacggtgt tttataatca ggcgtgaaaa cattaacacc
     2281 caaacgaata tacccgcatt gtaatgtgtt tctcgcatca gcagataagt actactacct
     2341 ttaggaaacc agccacggag ttccatcgcg gcataggtta ttgcaacgaa aagcagcgtt
     2401 atccaatgta aataaatttg agtttttgag aatcggttca tttttgtagc tcctgtaatt
     2461 tttacagtca agctatccca cgaaccttaa aaaatcctta tacagatgtg gttttaagaa
     2521 tttgttattt aaaaaattga tagtgcacat tgtaaccagc caatataagc aatggcgtga
     2581 gcacaggtat ctttctctgt tggccgtatt gtgtatggaa tccgttattg gttaactcaa
     2641 tgcgggttag cttattaata tacagacacg tcatagtgat gagcgtgtct gtagctagct
     2701 tgcgttcagt ggcgtttgtg gatggaccag tggcagttat gatgacttac taaagcggca
     2761 tcgaggcgtt atcatgagaa tactcaatga gacatcattt cctcgaccac ttcttcgcta
     2821 ctcaactgat atggataata cgttggccag ttttccattt catttaataa agattgctgt
     2881 gaatcattac ccataaaaat gtgaaaatga gatgattttc gtggtgcaat tatatgatcg
     2941 ctaaattgta tatatttagg ggctttgctt tcaggatctt tacattcgaa taagtaacga
     3001 acgcctttct tgcctgattt ataggtgagt attttgtatc catcgtaatc atatttacag
     3061 gatgttgttt cattatttct atggaattca acaatgccgt cctcaatgcc aatcatctcg
     3121 atatctgttg cataaccttt gtgataataa tctttaattt cagcaaatgt tttagtttta
     3181 tctgcatccg ctttcttctg aaagacgggg tcaagtttgc cactttgcag taaaggataa
     3241 acggattgcc agactccatc ccagtcactg agcgttcggt tttgtacatt ggcatcatca
     3301 aaaacaccat tagcagcttt ttgttcgacc tctgttaagg gtttgccgtg tgagtgatga
     3361 ccatgcgaaa aggcaggagc gctaacaata aagacaccta aagcaacagc cagtttgtga
     3421 agacgaatcg ccaaaacagt ttcctccaga gtcattgtat atgatgtgta atgttatatt
     3481 gtaacatatg gcaaaatgca acaactctta ggagatgaga gcatagtttt ctcaggtgta
     3541 attatctatc ttattgaaat aaaatgaatt atattgataa tttgaggttg atgacaaacg
     3601 aaacataacc tgatgtgatc tgcgtaggcc ggatagggcg ctcgcgccgc atccggcagg
     3661 gataacgcgt actttgtcgg caatatgaag ttatacagat aatttgttgt gaacctgctt
     3721 gcgtaaccgg ttaaaaaggg aacgcaactt cttataccgt aaggctaaaa gcagtacagc
     3781 cagcccagcg tagatgagcg gttgcggtga aataatcttc actgaccaca gataatgtat
     3841 tggggccagg atcgcgacaa gatagacgaa attatgcaac tgttgccagt gcttgccgag
     3901 ttttcgctgc atcgcctggg ttgaagtaaa cgctaaagca agcaaaataa cccagctgat
     3961 aattcctaac gttaaataag gccgggtaat taactccttg cctaataacg ccagattatt
     4021 cacgcccagc tccagcaatg cgtaactggt taaatgcagt gtcgcccagg caaagcacca
     4081 taagcctaac aggcggcgag tgcgtatcaa taacggctgt tttgcgtagc gtgccagagg
     4141 tgtgattaac aaggtcgcca gcaaaaattt cagtgcagtg cgaccggtaa aatgctgaat
     4201 atctttcacc ggatcggcac ccagtccacc gtgattgatc gcccagacca gccagagaaa
     4261 cggcaacaat ccggcaagat gcaggctaac tttcagccat gtcacctgtt ttgctgtcag
     4321 acgcattcag aaattctccc gcaaatccag gccacgatac agcgatgcca cctggtcggc
     4381 gtaaccatta aacagtagcg ttggctggcg ctgaacatcg aggatgccgc ctgaaccaat
     4441 aaatcgttcg gtagcctgtg accagcgcgg gtgatcaaca tgcggattaa cgttggcgta
     4501 aaaaccgtat tcgtcaggcg ctgccagatt ccaggtggtt ggcggacgct cgcgggtcag
     4561 cttaatactg actatcgatt taatcccttt aaagccatat ttccacggta caatcagtcg
     4621 taccggcgcg ccattttgtg gcggtaacgc cttgccataa acacccacgg tcatcagtgt
     4681 gagcggatgc attgcttcgt cgagacgcaa tccttcgaca taaggatatt tcagcccgcc
     4741 gccgataaag cggtcctgct ggcctggcat ttgttccggt gcataaattg tttcgaaagc
     4801 gacatacttc gcattgctgg tgggttcggc aagcgccagc aatttgtgca gcggaaaacc
     4861 aatccacggc accaccatcg accatgcctc cacgcagcgc atacgataaa tacgctcttc
     4921 cagcgggaag cgacgggtta aatcatcgtg atcgagggtc aatggttttg ccacttcgcc
     4981 gctgattttc agtgtccatg gatcggtttt caggctacca gcattagcgg cgggatcggc
     5041 tttatccagc ccgaattcat agaagttgtt ataaccggag actttatcta ctggcgtcag
     5101 tggcaggtta ttttgccagg cggcaggctt gctgaactcc agcggttttc cggcgggggc
     5161 gggcgggcga tcgttccctt taaaccagct aagcagatcg gcatgcgcag cgtgaggcaa
     5221 agaaagtgca gctgcgctga tgcccagtgc ttttaacacc tgtcgacgct tcataaagaa
     5281 taccgactcg gccgtaacat ctgattcttt taaaaattga ttctttttca taagccatca
     5341 cacttttttg tcgttagcca gcaagagccg tttactgtta atctgtcagg gagtgccctc
     5401 cctaacagta gcagagatct gcttttacat atttatgcat taactgccac gataggttga
     5461 atacccatat tggctaagta ataaaggcac atgataatgc tcgttcactt tattaatatg
     5521 aaattcaacg gggatctcag ggaagaaact ttcaagattt tgtttcttga aatagtcccc
     5581 ggttttaaat acgacacggt aatcgccagt agtcgcagtt tgctcgggcc acagtgcctt
     5641 aattcgtcca tccttatctg ttttggcggt attaagttgt aaccagccgt tgtccgcttt
     5701 cttttcaaga gtgactgtca cgtcggcagc gggttttccg gtttgctggt tcaaaatgtg
     5761 cacgctaaga atgttttgtt gtgcggcata aaccaaagaa ggtaatgaaa atgctgccgt
     5821 tactacggag agtactaaat aacgctttaa catgtttata tccttgtcat gtgaatgagt
     5881 tttgaggata gcgaaaaagc ggccagggta accttacagc agcattacaa ttttgtaatg
     5941 aaccaggctg tttctataac atatgattta tggcatatta ttttcatgaa gattttactt
     6001 attgaagata atcaaaggac ccaggagtgg gtaacgcagg ggctttccga agcgggttat
     6061 gtcattgatg ccgtttctga tggcagagat gggctttatc ttgcgctgaa ggatgattat
     6121 gcattgatca ttctggatat tatgcttccg ggtatggatg gctggcagat cttacaaacg
     6181 ttaagaacag caaagcaaac ccctgttatt tgccttactg caagggattc tgtcgatgac
     6241 agagtcagag ggctggacag tggagcaaat gattatctgg taaaaccttt ttcattttct
     6301 gagttgctgg caagggttcg ggcacaatta aggcaacatc acgctttgaa ttcaacatta
     6361 gaaatcagtg gcttaagaat ggactctgta agtcaaagtg tgagcaggga caatatcagt
     6421 attacactga cgcgcaagga gtttcagtta ctttggctac tggcctccag agctggcgaa
     6481 attataccca gaacggttat tgcgagtgaa atttggggaa tcaactttga tagtgatacc
     6541 aatacggtgg atgtcgccat tcgcaggctc cgcgcaaaag ttgatgatcc ttttcctgaa
     6601 aagctaatcg ccacaatccg ggggatgggc tattcattcg tagcggtaaa aaaataatga
     6661 aaagattatc tataaccgtc cgtttaacct tgctttttat attgctgctg tctgttgctg
     6721 gcgctggaat tgtctggact ctctataatg gcctggcaag tgagttgaaa tggcgcgatg
     6781 atacaacact cattaaccgg acagcacaga tcaagcagtt gttaattgat ggggtaaatc
     6841 cagatacgtt acctgtatac tttaaccgga tgatggatgt tagtcaggat atcttgatca
     6901 ttcatggtga tagcatcaat aaaattgtta accggacaaa tgtcagtgat gacatgttaa
     6961 ataacatacc tgctagtgag acaatcagcg cagctggcat ttacagaagc attattaatg
     7021 atactgaggt tgatgcttta cgaattaata ttgatgaagt ttcgccatca ttaacggtta
     7081 ctgtggctaa attggcttca gccagacata acatgcttga acagtataaa attaatagca
     7141 ttataatttg cattgtcgcc attgtacttt gctcagtatt aagtccgctg ttaatcagaa
     7201 cgggattacg agagatcaaa aagttgagtg gtgtaacgga agcgctgaat tataacgata
     7261 gccgggagcc tgttgaggtt agcgcattac cgagagaact aaaacctctt gggcaggcgt
     7321 tgaataaaat gcatcaagcc ttagtcaaag attttgaacg cctaagtcaa tttgctgacg
     7381 atctcgctca tgaacttaga acgcccatta atgcattact gggtcagaat caggttacgc
     7441 tcagtcaaac cagaagtatc gctgaatatc aaaaaacaat tgccggtaac attgaagagc
     7501 tggaaaatat ttcgcggtta acagagaaca tactgtttct tgcccgggca gataaaaaca
     7561 atgttttggt gaaactggac tcgctttctc tcaataagga agtcgaaaat ttgttggatt
     7621 atcttgaata cctttcagac gagaaagaga tttgctttaa ggtcgagtgc aatcagcaaa
     7681 tctttgcgga taaaatttta ctgcaacgaa tgttatcgaa tcttattgtt aatgccatta
     7741 gatattcacc agaaaaatcg catattcata taaccagttt tcttgatacc aacggctatc
     7801 ttaatattga tgtcgccagt cctggaacga aaattcatga gcctgaaaaa ctcttccgta
     7861 gattttggcg gggagataat tcgcgtcatt ccgtaggtca gggactaggc ctttctttag
     7921 tcaaagcgat tgccgaatta catgggggaa gtgctacgta tcactatctc aataagcata
     7981 atgtgttccg gattacgtta ccgcaaagaa attaacataa ggcttcagta cgccataaat
     8041 taaccgtgaa aaaacgcagc cacgtcgtga gtactaacgc ggctgcgatt gattagcgct
     8101 tacattcaaa cgtaacaggg attaacccgc gtaagctgcc agcatttcct gcgccgccag
     8161 tttacccaac gcattcgctg caaaaggact gtcgccagtg agaactttac ggtccttatg
     8221 tactcgcccg gtgatgtcgt cattaataat gttcatgccc attttcttca gctcttcgcc
     8281 gaagtaccag gtgagatgac ccggcatata gcctatctct ggcgtttgtt tgtctgcggc
     8341 gtctgggaat gcgcaaatgg aataaccatt cagtgggtta tcgccgtggc gaagcgccag
     8401 aaaagccgcc gggccgtggc aaagggagat aacaaaacgg tcatttttga ttgcccactg
     8461 caaagcagca gctacgtcct ggctttctgg taaaccaata agtgcgccat gaccaccagg
     8521 aacaaagatt gctgcatatt cgctatcagc gttgaggctg gcgacaacat ccgcgagttt
     8581 cttcggattg cggaacaacg atttatgttg ctcaaagaat ggcattactt tttcatcttt
     8641 gtgcggcata gcccagtatt caaacttggt catcagaccg gaaatggtcg ccacttcgaa
     8701 ttcgaaacct gcagcatgga gatgatacaa cggcagcaac gtttcaatcg gatggttacc
     8761 ggtcgagaac agttttccgt tatcggttgg caaataacgt tcgtccgcgg cgatcaccag
     8821 aattttatgc ttaccgcgat acggttttgg atagtccacg ccatcaagat cagagacggg
     8881 actggtatat tggctaagcg aatattctga agggaagaat gcattatctt cagcaatatc
     8941 gacctgcgga tttttacttg tttgaacagt catagtgtat tccttattgt tgcttagtta
     9001 gggtagtcac tatatttgcg actgagctgg tcgctatttt taaccagtct ggaaaattga
     9061 gtcaatatat cgaaagcggt agtcggcggg tgtaagtatg taatgatgat gctgcactgg
     9121 tgttgaatat tattcacgcc aaattttcct tattgagcaa cgtcgtcgca agtggcctca
     9181 atgattttag accattatca aaggtacggg gcggcgggga gagatttagt gctgtgaaat
     9241 attgtggtac tgatgaatat ttatatcgcg gattggtaga gaaaagatta tttcatgcac
     9301 tatttttgca aatatttcta tatgggaagc gtgtttgtta cggggtaatt catcagaatg
     9361 tgcatttggg gtgttggctg gaagagtcgc tggtagatgt tattgtggca ggaggggcag
     9421 ggtaaggtgc tgtatcgata tgctttggca attgcgtgtg ccgcagatgg agatgaaatg
     9481 ccaataaaaa aagcctgagt tcgatgaggg acgaactcag gctagtgtta tgttttacag
     9541 taacacgccg cggcgcgttg gctgattaga actggtagac gataccaact gcaaactggt
     9601 catcagttgc ggcatcggta atcgctgcat cgtctttatc cagcaggtta aatttgtatg
     9661 ctgtgtagac gttcatgttc ttattgaagt agtaccaggt accaacttcg atataattta
     9721 cgcggtcagc atcaacacct ttatgtccat tacgagcata aagatctttg cctttggaat
     9781 atacgtagcc taaagacgga cgtaaaccga agtcgaactg atactgtaca acagcttcaa
     9841 agttttgggt tttatttgca aaatgatcat tagccaaaac ggtcatgttg cgggtttcac
     9901 cgtacatcat tgctgcatag atattatttg catcatactt ggctgctaat gaccacactt
     9961 cagcgttatc accgtagccg tcaccagctt gttcattagt acgatcagat ttgctatatg
    10021 cacctacaaa accaaaacct tcgatgttgt agtctacaga caacgcatag ccatcaccgt
    10081 tttgtttagt aacgccacga ttgctgttct taccttgata ttgcacagca aaattcagac
    10141 catcaaccag accaaagaaa tcagagttac ggtaggttgc aacaccgttg gtacgaccgt
    10201 tcatgaagtt gtcagcggaa gcccaggaat caccacccca ttcaactaac atatcggtat
    10261 aagctgcggc atcataagca acaccgtagt tacgaccata gtcgaaagat cctaactcgt
    10321 tatatttcaa acctgcgaag gttaaacggg ttttttcctg attagagcct tcgggcttgc
    10381 tggcgtcgag gttgtattca aactgaccaa aaccagtcag ttcgctggtg atttgggttt
    10441 cacctttaac accgaaacga gcataggagg tatcttcgtt ttcgctgtta ttatcatcag
    10501 tatttgacca gatgcgttcg ccaaccatct tgccgtagaa atcaacttta ttgccatctt
    10561 tattgtaaat ttcagccgca tttgctgcgc cagcaactaa taacgccggg accagcattg
    10621 ccagaacttt tcttttcatt atgtattccc ttgtgattat aatcttcatg aatatatcaa
    10681 taagtgccgt tatccaaaaa aaagcacatt tggatactat
//
LOCUS       DAZUDJ010000120        10527 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.122, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000120 DAZUDJ010000000
VERSION     DAZUDJ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10527
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.122"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1060..1242
                     /locus_tag="ACHY1N_004625"
     CDS             1060..1242
                     /locus_tag="ACHY1N_004625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046802.1"
                     /translation="MARPVKFTREIVLEMAKRYFELTPDVVMGEWFKGEGIDQSTFHK
                     LLKKYDIKVKITAEVW"
     gene            1356..2297
                     /locus_tag="ACHY1N_004626"
     CDS             1356..2297
                     /locus_tag="ACHY1N_004626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000898986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046803.1"
                     /translation="MLFSANFFTNEVTNAKAVIKFGTEANKKIQPKVVAHVSFAQQKS
                     AFAGFKAHREALIAAGFGVDGKLPNGIRKAIDRVKPAKDVAVDHIVTFTVKNSSELFH
                     LVIAGDTAIVSAPNMDFQDTADCQITFGRRKEVTGKAKLNFTKSGNPYFAVFFNSHAT
                     EKEVVELVAYEGEEKERIESCEAFLELEAQVNAVSPVVEDRFAALEAQIAELKAALEE
                     KDQIIEAQKAEIEELKAKEVAPVAVVENAADEAANDEVEVKIDVMRDPMAALQLLRSF
                     KGKSHFSSDVEDEEEEQKRNAAMLHDEMYGTNFSYCQ"
     gene            complement(2582..2866)
                     /locus_tag="ACHY1N_004627"
     CDS             complement(2582..2866)
                     /locus_tag="ACHY1N_004627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000190127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046804.1"
                     /translation="MATFITYAVIITILAVISAYKLGTENRERAELFLGAFVAFASLA
                     LIVEGISYIVGLVSMTLFNFHPAISMHLLLTVCWVYCLIEFLTFVFKQTK"
     gene            complement(2961..3512)
                     /locus_tag="ACHY1N_004628"
     CDS             complement(2961..3512)
                     /locus_tag="ACHY1N_004628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046805.1"
                     /translation="MKEELTLTEISRLYGYTINAAKKWQERGMPFNTNTRRVPLKEGT
                     EWIAKNIISPLRETTVKEQIDVEKLRRERALADAAERENQEAMNLLIPVGYVEQQLAE
                     YCGKVKQTILQIATIDALEILESATDQKTLKNKLREIIERRLNEVGDLFENADFGEDE
                     EEELPLMDEPEQEPEEDDEFDVS"
     gene            3812..4117
                     /locus_tag="ACHY1N_004629"
     CDS             3812..4117
                     /locus_tag="ACHY1N_004629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046806.1"
                     /translation="MKTKDIKIDFETVDDVREHRIDSTGCIFQLTNSPIGLIIYVAED
                     DVYAIWDGQDEFKGGNSHLINTHEGFDPTPVCMLAYHVTLDELPEASARIRRMKDIK"
     gene            complement(4201..4605)
                     /gene="ycdX"
                     /locus_tag="ACHY1N_004630"
                     /pseudo
     CDS             complement(4201..4605)
                     /gene="ycdX"
                     /locus_tag="ACHY1N_004630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309438.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding phosphatase"
     gene            complement(4660..5598)
                     /gene="ghrA"
                     /locus_tag="ACHY1N_004631"
     CDS             complement(4660..5598)
                     /gene="ghrA"
                     /locus_tag="ACHY1N_004631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415551.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016618 - hydroxypyruvate reductase
                     [NAD(P)H] activity [Evidence IEA];
                     GO_function: GO:0030267 - glyoxylate reductase (NADPH)
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HFS4046807.1"
                     /translation="MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALV
                     WHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLNPSVPLFRLEDTGMGEQMQEY
                     AVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRF
                     PLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPD
                     GAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHV
                     AAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY"
     gene            5832..5919
                     /locus_tag="ACHY1N_004632"
     tRNA            5832..5919
                     /locus_tag="ACHY1N_004632"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5866..5868,aa:Ser,seq:gga)
     gene            complement(6069..6350)
                     /locus_tag="ACHY1N_004633"
                     /pseudo
     CDS             complement(6069..6350)
                     /locus_tag="ACHY1N_004633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309436.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
     gene            complement(6632..7636)
                     /locus_tag="ACHY1N_004634"
     CDS             complement(6632..7636)
                     /locus_tag="ACHY1N_004634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001179707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element ISSfl8 family transposase"
                     /protein_id="HFS4046808.1"
                     /translation="MQNITLIGIDLGKHSFHIHCQDKSGKALLRKKFTRTKLMQFLAT
                     CPPSVVVMEACAGAHFMARCISDFGHETKLISPQFVRPFVKSNKNDFVDAEAICEAAS
                     RPSMRFVQPRTETQQAMRALHRVRESLIRDKVKTTNQIHGFLLEFGISLPIGDAVIKR
                     LSLVLAEHEIPEYLSRLLVRLHTHYFYLVEQIAELESELSQSINADDTAQRIMTIPGV
                     GPITASLLSSQLGDGKQFSCSRDFAASTGLVPRQYSTGGKSTLLGISKRGDKNLRRLL
                     VQCARSFIMRLERKHGKLAEWVREQLNKKHSNVVTCALANKLARIAWAITTQKKEYQA
                     "
     gene            complement(7708..8268)
                     /locus_tag="ACHY1N_004635"
                     /pseudo
     CDS             complement(7708..8268)
                     /locus_tag="ACHY1N_004635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309436.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
     gene            complement(8353..8550)
                     /locus_tag="ACHY1N_004636"
     CDS             complement(8353..8550)
                     /locus_tag="ACHY1N_004636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HFS4046809.1"
                     /translation="MKSLTTETALDILIAWLQDNIDCESGIIFDNDEDKTDSAALLPC
                     IEQAREDIRTLRQLQLLHQNR"
     gene            complement(8562..9050)
                     /locus_tag="ACHY1N_004637"
     CDS             complement(8562..9050)
                     /locus_tag="ACHY1N_004637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5983 family protein"
                     /protein_id="HFS4046810.1"
                     /translation="MKLALTLEADSVNVQALNMGRIVVDVDGVTLAELINVVCENGYS
                     LRVVDESDRTSAERTPPSAALTGIRCSTAHITAKDNAWLYSLSHQTNGTGESEWIHFT
                     GSGYLLRTGAWSYPVLRFKRLGLSKTFRRLVVTLTRRYGVSLIHLDASAECLPGLPTF
                     DW"
     gene            complement(9047..9424)
                     /locus_tag="ACHY1N_004638"
     CDS             complement(9047..9424)
                     /locus_tag="ACHY1N_004638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001757701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TA system toxin CbtA family protein"
                     /protein_id="HFS4046811.1"
                     /translation="MKTLPDTHVREASRCPSPVIIWQILLTRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGFSACTRSQLINSIDILRARRATG
                     LMTRDNYRTVDNITLGKHPEAKR"
     gene            complement(9514..9882)
                     /gene="cbeA"
                     /locus_tag="ACHY1N_004639"
     CDS             complement(9514..9882)
                     /gene="cbeA"
                     /locus_tag="ACHY1N_004639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system cytoskeleton
                     bundling-enhancing antitoxin CbeA"
                     /protein_id="HFS4046812.1"
                     /translation="MSDTLPGTTHPDDNNDRPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSGELNPRHQHTVTLYAKGLTCDAD
                     TLGSCGYVYLAVYPTPETKK"
     gene            complement(9962..10183)
                     /locus_tag="ACHY1N_004640"
     CDS             complement(9962..10183)
                     /locus_tag="ACHY1N_004640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HFS4046813.1"
                     /translation="MKIITRGEAMRIHQQHPTSRLFPFCTGKYRWHGSTDTYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            complement(10246..>10527)
                     /locus_tag="ACHY1N_004641"
     CDS             complement(10246..>10527)
                     /locus_tag="ACHY1N_004641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HFS4046814.1"
                     /translation="NQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAAVVLAHNH
                     PSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGNQVFSFAEHGLL"
BASE COUNT         2776 a         2349 c         2472 g         2930 t
ORIGIN      
        1 agttatcatc tagtattaaa atccctttct aagaaaatcc tttcaaaagt gattctcgat
       61 gccacgcagt ggcgtcgcag acgtttgaga gtgagcgaag cgagcgagca aactagttaa
      121 ttccttctaa gaccatctag tatcatctag tttaaattag ttgttactag aagtaattgg
      181 ttagcgcttc gcgcagtcgg gctacgccct cctaatatct ttttggttat ttgttgtttt
      241 tggttttaca catgagcgta gcgaatgtgt tatataatat ctatgcacgc ccgattcccc
      301 gttttacccc tcactaagtt aatgttttat aaagagtttt tcttaccaat ccttttcggg
      361 ggcaaatttc aggggcaaaa attagatttt caggggcaat tattggcatt tcaggggcaa
      421 aaatgagggg caaaatcact gtttcccaga atttcagggg caaaaatagt gggtttcagg
      481 ggcaaaaatg ggatagtgaa atctagggga ttttggttca ggggcaaaat tcaggggcaa
      541 ttttcatagt gtagtgctag tgtaggtttg aaagtccttt cttgacacta tgtaggtttg
      601 gtgctatact tgacaattcg agaaaaaatg tggtataata tttgtattga aagtgaaaat
      661 ttaccgattt tccttcctat tgttatcacc gtgttaaatt gttatatgtt tgtgaagatt
      721 tggatctgag agaaaatctt gtaacaaatc tttacaattc atagctcaat taatgctcac
      781 cgctttagca aaaagtgcta tgcatttttc taaattgatt gaataaacat caatttggtt
      841 aattcgtgtt cttctcttta gcaattcgtg ctgcggttta acacatttaa cacgtctgat
      901 aacatctgaa taacatttta acatatctct gttataaata catatataag agataaatgt
      961 gaggggttga aaaataaaat acaatcccca tataaataat agtgagcggt taacgctctt
     1021 ttttaagaaa tcattaatcc agatttagga ggatttaaga tggcacgacc tgttaagttc
     1081 actcgtgaaa tcgttttaga aatggcaaag cgttattttg aactgacacc tgatgtagtg
     1141 atgggtgaat ggtttaaagg tgaaggtatt gatcaatcaa ccttccacaa actcttaaag
     1201 aagtatgaca ttaaagtaaa gattaccgca gaggtgtggt aataaccttt cactgagaat
     1261 tatatgatgg ctttaaaaaa gaaaaagcct cccttgttgc agcaaaggag gcttgaaatg
     1321 aacaattaaa actaactttc cacggagtat ttataatgtt attttccgct aactttttca
     1381 ctaacgaagt aaccaacgct aaagcagtta tcaaatttgg caccgaagca aacaagaaga
     1441 ttcagccgaa agttgttgct catgtttcct ttgcgcagca gaaatccgct ttcgctggct
     1501 ttaaagcaca tcgtgaagca ctgatcgcgg ctggctttgg tgttgacggt aaactgccta
     1561 acggcattcg taaagcaatc gaccgcgtta aacctgctaa agacgttgca gtagaccaca
     1621 tcgttacttt taccgttaag aactcttctg aactgttcca cctggttatt gctggtgata
     1681 ctgctatcgt ttccgctcct aacatggatt ttcaggatac cgctgattgc cagatcacct
     1741 tcggtcgtcg taaagaagtt accggaaaag ctaaactgaa cttcactaaa tccggcaatc
     1801 cttactttgc tgttttcttt aacagccacg ctaccgaaaa agaagttgta gaactggttg
     1861 cttatgaagg tgaagagaaa gaacgtattg aatcttgcga agcatttctg gaactggaag
     1921 cacaggtgaa tgctgtttct ccggttgttg aagatcgctt tgctgcactg gaagcacaga
     1981 tcgcagaact gaaagctgca ctggaagaaa aagaccagat tatcgaagca cagaaagctg
     2041 agattgaaga actgaaagct aaagaagttg ctccggtagc agtagttgaa aacgcggctg
     2101 atgaggccgc aaatgatgaa gtagaagtga aaatcgatgt gatgcgtgat ccgatggctg
     2161 cactgcaatt acttcgttct tttaagggca aatctcattt ttctagtgat gtagaagatg
     2221 aggaagaaga acagaaacgc aatgctgcaa tgcttcatga tgaaatgtac ggtactaact
     2281 tttcttactg ccaataaaaa agggactccg aagagtccct agtaagttta ggttaggttt
     2341 tgcacaacaa agatgaggtt ataatgaaca taatgctaca ttattcttta aagccagaaa
     2401 aataaccgcc cccgaagggg cgggaggatt aatactcaat ctatacttgt tatgttttta
     2461 tgttgtatag tcactgacta tgaaaacact gtactgaatg tgttttatgg cttttaatcg
     2521 ggaactctct ttcgaaaatt ccctgttaaa accacataag gagaaatggc agattacaat
     2581 attatttagt ctgtttgaaa acaaacgtta aaaattcgat taagcaatat acccagcata
     2641 cagtaagcag tagatgcata gaaatagccg gatggaagtt aaaaagtgtc atactaacta
     2701 ggccaacaat ataagaaatt ccttcgacaa ttaacgcaag actagcaaat gcaacaaacg
     2761 cacctaagaa taattcagca cgttctctat tttcggttcc gagtttataa gcagaaataa
     2821 cagccagaat agtaatgatg acagcatagg taataaaagt agccatagtt ttatatcctc
     2881 ttaaaagtta agcgggggat gttctccccc gtagacgttg accagctcaa catctttcat
     2941 acatttattt ataacgcgtt ttaagacaca tcaaattcat cgtcttcttc tggttcttgt
     3001 tccggttcat ccattaatgg taattcttct tcctcgtctt caccaaaatc tgcattttcg
     3061 aacaagtccc ctacttcatt taaacgacgc tcgatgatct cccttagctt attcttcaat
     3121 gttttctgat cagtggcaga ttcgagaatt tctaaagcgt cgattgtggc gatctgcaaa
     3181 atagtctgct tcacttttcc gcaatattcc gctagttgct gttctacata cccgacagga
     3241 atcaggagat tcattgcttc ctggttctct cgttcggctg cgtccgctaa tgctctctcg
     3301 cggcgtaact tctctacgtc gatttgttct ttgacagtag tttccctgag tggactgatg
     3361 atattttttg ctatccattc ggtcccttcc ttgagcggta cgcgtcgtgt attggtgtta
     3421 aatggcattc ctcgttcttg ccatttctta gcggcgttaa ttgtatagcc gtataagcgg
     3481 gaaatttctg taagggttaa ttcttctttc atccggttat cctccattaa atttgcgtaa
     3541 aattatttat ctgatctgcg cattcaggag agcgcctaaa acgctttata acgaagggaa
     3601 agatcgaggc gaggaaaggg attggctggt gttaatagtc gcgtagcgac cgcgctggtg
     3661 ggctgcactg cacctgtttt gaaatctcac acgcacatca aaaaccgggg tgccgaaaac
     3721 tcgctttatt tcacccgtgg aacagtacct tttgatttgg tcaagtcttt tttataaata
     3781 atcgaaaata tttttcacac gagggcaaat catgaagact aaagatatta agattgactt
     3841 tgaaactgtt gatgacgttc gggaacatcg tattgattct actggctgca tcttccagct
     3901 tactaactcc cctattggat tgattatcta tgtagcagaa gatgacgtgt acgctatatg
     3961 ggatggacag gatgaattta aaggcgggaa tagccatctg atcaatactc atgagggatt
     4021 tgatccgact cctgtctgta tgcttgctta tcacgtaaca ctggatgaac taccggaagc
     4081 aagcgcgcgt atccgtagaa tgaaagatat taagtgatgt aagtaattga ttctatagcc
     4141 ctgtccttgt gatggggctt ttttattgga aatcgggtgt tattgggggt tgactacgtt
     4201 cgggtttccg ggatggctta ttatatgcac attgccgctg gcgatagtgg cgatcatcgc
     4261 ttgtgtattg gtcgctttgt catgtggtgc aaaaaccggc tcatgaaaac cggcaataat
     4321 cagatccagc gagtcaaaca ttttaccgct gcaatcaatt tcaccatcaa catttttaat
     4381 gttagcttcg atgccgcgca ggatccctac cccatcaacc actcgcggcc agatacgcat
     4441 gttaatgaag tgccagtgat gcggagcatc ttccatatcc gggccatgat cggtgatcgc
     4501 aaaaagttta atgccctttt gtttggcctg ggcaatgtaa tcactcaatg tgctatatgc
     4561 atgtgtgctg gcaacggtat gcatatgaag gtcgacggga tacataactc tctcctgtat
     4621 tcaattcccg ccaaggatag caggaatcct gatgctttat tagtagccgc gtgcgcggtc
     4681 gacttgcccg cagaccctct cccctttttc gagctgggca atggtgcgag aaatgtactc
     4741 cacagcttca gcgggacggg taatcgcggc gacatgtggt gttatcgtca cgcgtggatg
     4801 ttgccagagc ggactttcag gcggtaaggg ttcacgatta aaaacatcca acattgcgcc
     4861 tttaactttg ccgctatcca gcgccgcgag caggtcatct tccacaacat gaacaccacg
     4921 cgccaggttg aggagatacg cgccatccgg taatttttcg agtaattgtt gattaataat
     4981 gccgacggtt tcaggggtat tcggtaacaa attaatcaat acccgacatt ggctcagaaa
     5041 tgcagacagt tcttcccgtc cggcaaagct ttgcacgcca ggccacgatt tacgggttcg
     5101 actccagcaa cgcagcggaa agcgccaggt ttgcagactc tgagcaactt tactgcccag
     5161 tacgcctgcg cccaaaatgc cgatggtaaa atcttcccga tgatattcag gcagcggttg
     5221 ccaatgcgaa ctattttgct ggatgcgata atcgtcaaaa cgtcgaaacc aatgcagcac
     5281 ctgactgaca gcatattcct gcatttgctc gcccataccg gtatcttcca ggcgaaaaag
     5341 tggaacagaa gggttcagca tttcagggtg tgcctgtagc ttgctcaaaa tagaatcaac
     5401 accggccccg agtgcgaaca ccgctttaag atcgcgccct gccagcattt caacaggagg
     5461 atgccagact aaagcataat cagcagagtc attatctccg cttttccatg ctctgactct
     5521 tgcctgagga atagctttgc gcagtgcctc aatccaccat tgggtatcga acgttgggtg
     5581 ataaaagatg atatccatac tgactcccga aaagcgttgt gcgaaattta ttcgcactta
     5641 tcgttatgat ctacaaaggc caccagcata acaaatccgt ggtcggtggc aaaaaaagca
     5701 gatttcgctt actaaaacca cacattgatt gaagtttgaa taaacgcgcg attttttcaa
     5761 aaagtttgtt gacctcaggt catgatttcc ctaaattagc gcccgttcca gcaagacagg
     5821 aacgacaatt tggtgaggtg tccgagtggc tgaaggagca cgcctggaaa gtgtgtatac
     5881 ggcaacgtat cgggggttcg aatccccccc tcaccgccag attacaagcg catgttattg
     5941 tttaacatgc gcttttttat ttatccttcc agacagtatg ccaccgggta tgccatctga
     6001 aaccggtttg tatgagccgc gatcacatct tatcggacaa tttccgatct ttgagcatac
     6061 tggcaaagct atactgacag catgtcagga tagtgttctg caataatatc attcagtcgg
     6121 tcaaccagtt ccggttttct gaacgtgata tgcgcggagc ccttcctaaa gtatctgatg
     6181 ctgaacatct catcttcata gctctcttta ccctgaacag actgaatgtg atcatccaga
     6241 cgaatagtga tgttttcccg gttgtcgggg attggtttac cgctgaacag gtgcaacatt
     6301 ctttccagat cggcgagtcg gtcagcctgt tgtccggtga taagatgaaa tctatggtca
     6361 cccccgtttt tgcaacactg atttttgatt aatggttggc ttgcttaaat ctatccggcg
     6421 tctctgtggg caaggatgcc cgcgccccga tgagttccgc acctgataat cctaaaaatc
     6481 ccctcggctt cagtgagcca tttcatctgt taggttttta atcaggtcga tttgccgttc
     6541 atgtcatcaa taatcagtct tcgcaaaacc agaaaggtaa cttgtatctt attgtttaaa
     6601 ataaactaat tgagttatat cagcatctat atcaggcctg atattctttt ttctgagtag
     6661 tgattgccca ggcaattcga gccagtttat ttgccagagc gcaggtaacc acattcgaat
     6721 gcttcttgtt gagttgctcc cgaacccact cagcaagttt tccatgcttg cgttcaagtc
     6781 gcattatgaa tgagcgggca cactgaacca gtaaccggcg taaattttta tcacctcgct
     6841 tactgatacc caacagagtc gattttcctc cagtgctata ctgccgggga acaagtcctg
     6901 tggaagctgc aaaatccctg ctgcatgaga actgtttccc gtcaccaagt tgcgacgata
     6961 gtaagctggc agtaatcgga ccaacaccag gaattgtcat aatgcgctga gcggtatcat
     7021 cagcgttgat tgactgactt aattctgatt ccagctctgc tatttgctca acaaggtaaa
     7081 agtagtgggt atgcaacctc accaaaaggc ggctcagata ttcggggatt tcgtgttcag
     7141 ccaacacgag agacaaccgt tttattacag catcacctat cggcaggctg attccaaatt
     7201 ccagcaagaa accgtggatc tggttggttg ttttcacctt atctctgatg agcgattctc
     7261 tgacccggtg taacgccctc atggcctgct gggtctcagt tcttggctgg acaaaacgca
     7321 ttgatggtcg tgaagccgct tcgcatatgg cttctgcatc aacaaaatca ttcttattac
     7381 ttttgacaaa cgggcgaacg aactgtggag aaatcagctt agtttcatgc ccaaaatcag
     7441 agatacagcg agccataaag tgtgcacccg cacaggcttc cattacaaca actgagggcg
     7501 gacatgtcgc cagaaactgc atcagtttag tacgggtaaa ttttttacgc agaagagcct
     7561 taccagactt gtcttgacaa tgaatgtgga aggagtgctt tccgagatcg ataccaataa
     7621 gtgtgatgtt ctgcatgatg gtctctccgt taaagggatt taccttaaca gcgtactgct
     7681 gttaaggtgg gggtgaccat atcattatcc ccaccggtcc catctcacca gattgttgac
     7741 gataatttta ctgccaaatt tacaggggca attggttttg taattccagt tcagccctct
     7801 gaagacgttg atcacccctc gctcaaacac ctcatcctta ttctggtgca gttgttcaaa
     7861 tgtgctcagg atgttcgctt cgctgatttc cggaaaatta tcgtactcca gtgaccggta
     7921 ccatgtctca cgggcctgtg catccattaa ggaaagcatc ccggaacgtt gcatcaggtc
     7981 acgccagatt tcgcggtcaa gattgcgggt gatagctttc attgccgttt cagttttctc
     8041 catcagccag cagccgcagc gaaaatcctg tttcatcgcc cagtccagtg cggttttacc
     8101 gccaatactt tctgtcattg ctgagatttc agccagttgc cggataagtg tgtcgatttg
     8161 cagcagtgta ctttttcgta cagccagaat gtggcggata ctggttgagc agataacgtc
     8221 cgtatgcccg gtgagcagtt ccggacggga gattgtgatg tctgacatta tcggtttccc
     8281 tttgggttta taaacgaaaa cgccagccct gttcaggctg acgtcagtgg aatgaagtct
     8341 ggtgagtgag actcaccggt tctggtgcag aagctgcaac tggcgcagtg tacggatatc
     8401 ttccctggcc tgttcaatgc agggcagcag tgctgccgaa tccgttttat cctcatcgtt
     8461 gtcaaagata attcccgatt cgcagtcgat attgtcctgc agccacgcaa tcagaatatc
     8521 cagcgctgtt tccgtggtta atgatttcat gttgtttctg gttaccagtc gaaagtgggt
     8581 aaacccggca ggcattcagc gctggcatcc agatgaatga gactgacgcc ataacgtcgg
     8641 gtaagtgtga caaccagacg acggaacgtt tttgacagcc ccaggcgttt aaaccgcaga
     8701 accgggtacg accacgcacc ggtacgtaac agatatccgc tacctgtaaa atgaatccat
     8761 tctgattcgc cggtgccatt cgtctgatgt gacagcgagt acagccaggc gttgtccttt
     8821 gccgtgatat gcgcggtact gcagcgtatg ccggtaaggg ccgcagatgg tggcgtgcgc
     8881 tctgctgatg tccggtcaga ttcatcaaca acacgaaggg agtaaccgtt ctcgcagacc
     8941 acgttaatca gttcagcgag agtaacacca tcgacgtcaa cgacaatgcg ccccatgttc
     9001 agtgcctgca cgttaacgct gtcggcttcc agcgtcaggg ccagtttcat cgtttcgcct
     9061 ccggatgctt ccccagggta atgttatcta ccgttctgta attgtcgcgg gtcatcaggc
     9121 cggtcgccct gcgagcccgg aggatatcga tgctgtttat taactgagag cgggtacagg
     9181 cgctgaatcc cggctggtcg gtacgcacca gcgcgtattt ttccacgaga aagttcaccg
     9241 catcacacag tgaaatgcct gcctcaatat gctgctcaat cacacgttca tcggcaaacg
     9301 gtgtgtcatt cagtgtgagg ccgtagtgct ggtccagcag tcgggtgagc agaatctgcc
     9361 agatgatgac gggagacggg cagcgcgatg cctcccgtac gtgtgtatcg ggtaatgttt
     9421 tcatactgaa gattttcctg atatgcaaag atgaaaaatg ggaaagtggt gtggtgaaag
     9481 caccagaccg gagcagacga ttattcctgt ggtttacttt ttcgtttcgg gggtcggata
     9541 aacagccaga taaacgtaac cacaggagcc gagggtgtcg gcatcgcagg tcagcccttt
     9601 agcatatagc gtgacggtat gctgatggcg gggattcagt tcaccgctgg tgagcatgag
     9661 ttccagttgt ttcatcagca gcggaaaggc ctggtccaga tggtacgcat ccgcgtcgct
     9721 gaaccggcct ctgataccgg cgcggtctgc aaggtaatgc aaccggttac cctcctgcac
     9781 cagacgtgcc ccaaaacagg gcgtcacggt gcagggtagc ccccaccagg ggcggtcgtt
     9841 gttatcgtcg ggatgcgttg tcccggggag agtgtctgac acgataaaat cctcacagaa
     9901 aattggttaa gaatggtccg gtggtggcga taattctgct cttctgaatg cccttccaga
     9961 ctcagttcag ggtgacgctc atcagccgga catacggacc aaaactgtcc ttacggcgtt
    10021 ctgcaaacac agccagcaca ccgggaatat cctgtacttc acggccggta tatgtatccg
    10081 tgctgccgtg ccagcggtat ttgccggtac agaacgggaa aagacgggat gtcggatgtt
    10141 gttggtgaat acgcatggct tcaccacggg tgataatttt cataatggga tacctctgaa
    10201 gacagaagat aaaagtgaaa acaggtgtga tgtggttgtg acgggttaaa gcagaccatg
    10261 ttcggcaaag gagaaaacct ggttgccacc gactatcaga tggtccggca cccggatatc
    10321 caccaggccc agtgcctgta ccagacgttc ggtgataagc cggtctgcct tactgggtgt
    10381 gacttcaccg gacgggtgat tgtgcgccag caccacggca gcggcattgt ggtacagggc
    10441 gcgtttaatc acttcccggg gatggacttc cgtgcggttg atggtgccgg tgaagagggt
    10501 ttcaccggca atcagctgat tctggtt
//
LOCUS       DAZUDJ010000121         9671 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.123, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000121 DAZUDJ010000000
VERSION     DAZUDJ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9671
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.123"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(204..971)
                     /gene="fecE"
                     /locus_tag="ACHY1N_004642"
     CDS             complement(204..971)
                     /gene="fecE"
                     /locus_tag="ACHY1N_004642"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter ATP-binding
                     protein FecE"
                     /protein_id="HFS4046815.1"
                     /translation="MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTL
                     LNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRN
                     PWLSLWGHLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVV
                     LLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMA
                     QGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR"
     gene            complement(972..1928)
                     /gene="fecD"
                     /locus_tag="ACHY1N_004643"
     CDS             complement(972..1928)
                     /gene="fecD"
                     /locus_tag="ACHY1N_004643"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter permease
                     subunit FecD"
                     /protein_id="HFS4046816.1"
                     /translation="MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGREHY
                     YVLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLL
                     MPSLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSR
                     PQDVNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLG
                     VSVPHTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTG
                     ALLLVVADLLARIIYPPLELPVGVLTAIIGAPWFVWLLVRMR"
     gene            complement(1925..2923)
                     /gene="fecC"
                     /locus_tag="ACHY1N_004644"
     CDS             complement(1925..2923)
                     /gene="fecC"
                     /locus_tag="ACHY1N_004644"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate ABC transporter permease FecC"
                     /protein_id="HFS4046817.1"
                     /translation="MTAIKHPVLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALL
                     PGQTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAA
                     LAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
                     AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQL
                     NLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAG
                     FDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG"
     gene            complement(2920..3822)
                     /gene="fecB"
                     /locus_tag="ACHY1N_004645"
     CDS             complement(2920..3822)
                     /gene="fecB"
                     /locus_tag="ACHY1N_004645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter
                     substrate-binding protein FecB"
                     /protein_id="HFS4046818.1"
                     /translation="MLAFIRFLFAGLLLVISHAFAATVQDEHGTFTLEKTPQRIVVLE
                     LSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDL
                     IIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQH
                     KERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGASMPS
                     IGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRG
                     IFAAERIAADTVKIFHHQPLTVVK"
     gene            complement(3867..6191)
                     /gene="fecA"
                     /locus_tag="ACHY1N_004646"
     CDS             complement(3867..6191)
                     /gene="fecA"
                     /locus_tag="ACHY1N_004646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent Fe(3+) dicitrate receptor FecA"
                     /protein_id="HFS4046819.1"
                     /translation="MTPLRVFRKTTPLVNAIRLSLLPLAGLSFSAFAAQVNIAPGSLD
                     KALNQYAAHSGITLSVDAGLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSW
                     TLEPALAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRI
                     PGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPVS
                     LGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPK
                     ETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLL
                     QYYDGEADMPGGLSRADYDADRWQSTRSYDRFWGRRKLASLGYQFQPDSQHKFNIQGF
                     YTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYVNESTHE
                     MRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQ
                     NNAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVE
                     PEKARTWELGTRYDDGALTAEMGLFLINFNNQYGSNQTNDTVTARGKTRHTGLETQAR
                     YDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTF
                     NLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKN
                     IFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF"
     gene            complement(6278..7231)
                     /gene="fecR"
                     /locus_tag="ACHY1N_004647"
     CDS             complement(6278..7231)
                     /gene="fecR"
                     /locus_tag="ACHY1N_004647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric citrate uptake sigma factor regulator
                     FecR"
                     /protein_id="HFS4046820.1"
                     /translation="MNPLLTDSRRQALRSASHWYAVLSGERVSPQQEARWQQWYEQDQ
                     DNQWAWQQVENLRNQLGGVPGDVASRALHDTRLTRRHVMKGLLLLLGASGGWQLWQSE
                     TGEGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAITTA
                     KDALQRPFRVLTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKRIVNA
                     GESLQFSASEFGAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRCDPAVA
                     GLRLSGTFPLKNTDAILNVIAQTLPVKIQSITRYWINISPL"
     gene            complement(7228..7749)
                     /gene="fecI"
                     /locus_tag="ACHY1N_004648"
     CDS             complement(7228..7749)
                     /gene="fecI"
                     /locus_tag="ACHY1N_004648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FecI"
                     /protein_id="HFS4046821.1"
                     /translation="MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQD
                     TFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPE
                     ERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKA
                     VEHCLLFRLEYGL"
     gene            7886..7954
                     /gene="ykiE"
                     /locus_tag="ACHY1N_004649"
     CDS             7886..7954
                     /gene="ykiE"
                     /locus_tag="ACHY1N_004649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_010051215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YkiE"
                     /protein_id="HFS4046822.1"
                     /translation="MGWSLCFWHVSVKMTHDVVCYY"
     gene            8041..8732
                     /locus_tag="ACHY1N_004650"
                     /pseudo
     CDS             8041..8732
                     /locus_tag="ACHY1N_004650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558153.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(8918..>9671)
                     /locus_tag="ACHY1N_004651"
     CDS             complement(8918..>9671)
                     /locus_tag="ACHY1N_004651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4046823.1"
                     /translation="VMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALDLSRLPELLS
                     RIDGYKGQPVTRLAVMLNLLVFIRSSELRYARWSEIDIDNAMWTIPAEREPLPGVKFS
                     YRGSKMRTPHLVPLSQQAVAILAELQTWAGENGLIFTGAHDPRKPISENTVNKALRVM
                     GYDTTQDVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEER
                     RLMLQWWADFLDANREQCISPFEYAKINNPLK"
BASE COUNT         2144 a         2663 c         2726 g         2138 t
ORIGIN      
        1 cacgactggt ttgaaagccg cgcccaagcc tgtacagctc tggtttgcgt tgattatgaa
       61 cctgtcagcc taaagcaagc ggatggacga tgagtattgg taatctttca gagtccggaa
      121 aagttcagcc ccagtctgaa ctggcttgct ggcgccagtc cagtttcatt cagtcgtggt
      181 ttggttctta cggcctgtgc aatctacctc attaggcaca tcggcctgcc agataccggc
      241 tcggggtgta tttccgcttc cacgctgaat actgttctca gcaatcctgg ggtcatcacc
      301 tcttctggtg tgccttgcgc cataacatgc ccgtttgcca ttaccaccag ttgatcgcag
      361 taccggctag cctgattaag gtcgtgcagc acagcgacca ccgttttccc ctgagtccgg
      421 agttcgccca tcaaccgcat caggtccacc tggtgattga tatcaagata ggtggttggt
      481 tcatcaagta atacaacggg cgtattctgg gccaggacca tcgccagaaa tgcgcgctgg
      541 cgctgaccgc cggaaagctc ggttaaccga cgaacggcaa gatgattaat ccgggtctgg
      601 ttcatggcga cattaactcg tgcattgtct tcagcggaga gatgccccca gagtgacagc
      661 cagggattac gaccatacga aaccagctcc tggactgtga tcccctctgg cgttaaatgg
      721 tgctgaggca gcagcgaaag cctgcgggcc aactggcgcg atgagagcat atttatggga
      781 ttatcgccga gaaatacggt gccagactgc ggcattaaaa gccgcgaaaa acagtttaac
      841 agcgtcgatt tcccgcaacc gttaggaccg atcagggcgg tgatcttccc cgttggcagt
      901 gagagtgaaa cgtcgttaag taccttgtct gtcccgtaac tgaccgtcag attttcagtt
      961 cgtaaagtca tttatcgcat tctcacaagc aaccagacaa accacggcgc accgataatg
     1021 gcggtcagca cgccaaccgg gagctccagt gggggataaa taattctcgc cagcagatcg
     1081 gcaaccacca acagcaacgc acctgtcagg gccgaaacag gcagcagtct gcggtgacgt
     1141 ccaccggtga tgctacgcat catatgcggc accacgagac caataaagct aatcgggccg
     1201 caggcggcca cgccggtaga tgtcatggcg acagctagta acaaagccca gaatcgggta
     1261 tggggcaccg acacaccgag cgtggtggcg cgcgcatcgc cgagtgcaag gaggtcgaga
     1321 tcgcggcaaa aactcaggct cagcggcaga aataaaatca tcagcgggat ggcaatcttc
     1381 acaaagctcc agtcacggcc ccataagctg ccggtcagcc acagcagggc gttgttcaca
     1441 tcctgcgggc gcgagagcat cagataatcc gtcaggctgg cccagcatgc agaaagcgcc
     1501 acgccggtga gcgccagctt catcggctgg tgggtctttg ccagcatctt cagcaatatc
     1561 aaccccgcca tgccgcccgc aaaggccagc agcggcagca ccatcacggg cagtgacggc
     1621 ataagaagta gagcccccac agaggccagg ctggcggcat ggttaacgcc gagaatatcc
     1681 ggtgatgcca gagggttgcg cacaatcccc tgtatcagca cacccgccac ggcgagggct
     1741 gcaccgacaa acagtgccaa cagcaagcgc ggcagtcggt actccatcaa tacataataa
     1801 tgctcgcgtc cggcctgcca gtcggtcagc agcgcgcgcc acggcacggg gatcactccc
     1861 atatggagtg ataacagcgc acagcccgcc agggcaaggg tgatgaaaat aaccagcgca
     1921 attttcatcc tcgcctcctc acaagccaga caaagcaagg gctgccaatc agcgccagca
     1981 ctgcgcctgc gggcagatct ccggggaagg ccagcgcgcg tgcgagtaca tctgccagca
     2041 gcatcagcgt ggcccccagc agcatgctca ctggcagtac gttgcgctga tcgaagcctg
     2101 cccagaagcg cgccagatgt ggcaccagca gaccgataaa cgccaccgga cctgccacgc
     2161 tgacgcacgc accaaccaga agcagcacta acatattgat gaccaaacgt agcctcgtca
     2221 ggttcactcc cagcgtatgg gcggtgctgt cgctgaggtt gagcaggttc agttgattcg
     2281 ccagcagcaa cacgacaggg actgcagtga ccaccaccgg caagagctgc cagacatcct
     2341 gccagcgggc gtgggacact ccgcctgcca gccagtaaaa gatgccgtaa gcatgatctt
     2401 cggccagcag cagggtgatg cgggtaaggc ccatacaaaa ggccgacagc gcgatacccg
     2461 cgaggatcag tttgtttctg tcatgggtat gacgaaatcc gcctcctgcg gtcatgacca
     2521 gcagccagct cacgccgccc ccgcatgccg cgatgaacga cagagaatag cctgcaatcg
     2581 gcgtcggact cagcgcgctg gtaagcgcca tagccagcgc cgcgccgctg ttaatgccga
     2641 gcagtgaagg agaggccatt gggttgtggg tcagggtttg cagcagcgtg cccgcgagcg
     2701 ccaggcttgc gccgatcaga acggcgacga ggcttcgtgg caaacgaagg ttttgcacca
     2761 gcgcttctgg tagcgttggc gtttgtccag gcagcagggc gcgggttgca tctgctccgg
     2821 aaacaggaat ggccgagtag caaaacagac tcagccagaa aataataata agtgctgcaa
     2881 cgggaagccc ccacagcagc accgggtgtt ttatcgcggt catttcacaa cggtaagcgg
     2941 ctgatggtgg aagattttta ccgtgtcagc ggcaatacgc tctgcagcaa aaataccgcg
     3001 catccgcgcc caggtgttac tgtcgaccga agcaacctgc tgcttctgcg cggcggttaa
     3061 catctgccag agcggatctt gttgccagcg tttaacaatg ctctcttcgc gatagtgggc
     3121 aaccagcagc caggcaggat tgaccgccag cagttgctcc aggccgatgg acggcatgga
     3181 cgcacccgcc atcgcagcgg gaacgttcag ccccagagag gccagcacgc tgccggtcca
     3241 ggtctcctga gtatgcaggt tgaattgctg ttcgcgtgat gtgccaaagg ccacgcgtgt
     3301 ccctttggga agctggctgg cccactgcgc catcctctct ttatgttgtt ccagacgtgc
     3361 ctgcatctct cgctttttac ccaccatttc gccgatgata gccgcagatt gcaaattttc
     3421 agcgtaggtt tcgttgcggg acttaagcag cagtaccggc gcgatttgct gcaaggcgat
     3481 gtaaaccccc gcatggcgac tgctgtcggc aatgatcagg tctggtttca gagcggcaat
     3541 ggcttccagg ctcggctgcg cgcgcgttcc gacggactgc cacggtttca ggtgcgcacg
     3601 cacttcgggc aggatgcgtt ttgcatcgtt atcgtcggca ataccgatcg ggctgacgtc
     3661 cacggcggcc agcgcatcgg cgaacgagag ttccagcacc acaatccgtt gtggcgtttt
     3721 ttcgagtgta aacgtgccgt gttcgtcctg aaccgtggcg gcaaaggcgt ggctgatcac
     3781 cagcagcagg cctgcaaaaa gaaaacggat aaatgccaac ataatcacat tccagctaaa
     3841 agcccggcaa gccgggcgtt aacacatcag aacttcaacg acccctgcat atacagcgtg
     3901 cgcggctggc ctgcatagat gcctttgttg ttgtcgtcat aagagcggat gaagtagtcc
     3961 tggtcgaaga tgtttttcac accgaatgcc aggttcagat ctgccatctg cgggccaaag
     4021 tcatacgcca cgcgtgcgcc ccagagcatg aagccgggaa tgcggccggt actgccgtcg
     4081 gcgctctctt tcaccgtatt ggcgttatcc gcaaactggc tggactggaa atcgctgttc
     4141 agattgaacg tccagtttcc tggcttgtag tccacgccca gcgtgccttt atgtttcggg
     4201 gagaatggta ccagattgcc gtaggtgtcg cctttctcgc ggatttccgc gttcacatac
     4261 gcatagctgg cgtagatgga aacgttatca agcgttggcg ttagcgtacc cagatcgtaa
     4321 cgtgcctgcg tttccagccc ggtatggcgc gttttgccac gtgcagtgac ggtgtcgttg
     4381 gtctggttgg agccgtactg attgttaaag ttaatcagga acagccccat ttccgccgtc
     4441 agcgcgccgt cgtcgtagcg ggtaccgagt tcccaggttc gcgctttttc cggttccaca
     4501 ttgccgcttt gcacagcctt gccaatctgg ctgtactgta cggtgccgaa cgagccttca
     4561 gtgtttgcat aaagattcca gctgtcagtc aggtgataga gcacgttcaa cgccggaagc
     4621 ggtgcgttat agctcacttc ttcgtgcgtg cctgtgatgg cgttgttctg gtatgactcg
     4681 atatgttcga aacgcatacc cggcgtgatg gtccagttgc cgatgtcgat tttgtcatcc
     4741 agataccagg cgtgcgcctc ggtgccggaa cgcgtatcgc ggtcgtaagg gcttgagccg
     4801 gacggcaact gcccgctgct ggtggcggtg tagtaacgca tttcatgcgt tgattcattc
     4861 acatagcgat agcccacgcc cacttcgtgc gcggaagggc cgatcataaa gatctggctg
     4921 tagcgtggct caataccgcg cacccagtag ttacgcggcg agagggtgat gcgtttgcct
     4981 tgctccaggt agccgctgcg cagggtttgg gtgtagaacc cctgaatgtt gaatttatgc
     5041 tggctgtctg gctggaactg gtagcccagg ctcgccagct tgcgacgacc ccagaagcgg
     5101 tcatacgagc gggtggattg ccagcgatcg gcgtcgtaat ccgcgcgaga caggccaccg
     5161 ggcatgtcgg cttcaccgtc gtaatattgc agcaggctgt tgaaggtgtg cacctcatcc
     5221 ggcgcatatt tgcttttcag catcaggtcg tcgatgcggg tggcgctgtg ctcgcgccag
     5281 tcactgccgc gcgtgccgga gtagagcagc gcggtgccaa aaccgttgtc cgctgtgccg
     5341 cccaccatca ggttgtgcgt ctctttcggg ttgttttgtg aagaggttgg gctgagctga
     5401 ccttccacgc ccgcctcgat accaaagtcc tgcggaatgg cacgggtaac aaagttcacc
     5461 acgccgccca cgctctgcgg tccgtaacgc accgcaccac caccgcgtac cacgtcaatg
     5521 gcatccatgt tgccgagcga aacgggagcc agtgaaagct gcggctgacc gtaaggggcg
     5581 aaggggacgg ggatgccgtc catcaggacg gtcgagcggc tggcgaggcg cgggttcagg
     5641 ccccggatgc caaagttcat cgccaggtcg tggctgccgg tgccgttgtt ttccggcgcg
     5701 ctgacgccag ggatgcggtt aagtacctca cgcatggtgg ttgcgccggt tttggcgaaa
     5761 tcctcacggc ggatcacgtc acgcgcgcca gcatgttcaa atacgtcgtt ttcacgcgca
     5821 tcacccagcc agtcgccgac cacggtcagg gcatcttctt ttggtgcgag cgcgggctcc
     5881 agcgtccagc tgttatttcc cagcggtttt acctgcagtc cgctgccgtc cagcagttgt
     5941 tgcaggccgc tctcgacgtc gtaatcgccg tgcaggccgt tgctctgctt gccgcgcgtc
     6001 aggccggcgt caaccgagag ggtaattccg ctgtgtgcgg catactgatt gagcgcttta
     6061 tcgagcgatc ccggtgcgat attaacctgt gcagcaaaag cggaaaacga gagaccggcc
     6121 agcggcagca ggctcaggcg aatggcgtta accaaaggtg ttgttttacg aaaaacgcgt
     6181 aacggcgtca taccttcccc atcatcattt ttgttgtgtt cagctatgag tcgaacgaga
     6241 agggtaaaaa ggacaatcga aataagaatt attttcctta cagtggtgaa atgtttatcc
     6301 agtaccgcgt aatagactga attttaacgg gaagcgtttg cgcgataacg ttcaggatcg
     6361 catcggtatt tttcagcggg aacgtcccgc tcaggcgcag cccggcaacg gcgggatcgc
     6421 agcgcagcac gccgttgcgg taacgggtta gcgtggctat cacctcaccc agcggtttat
     6481 cgctgaagct caggatgtcc ttcgtccagc ttgtactctc gtcatccagc ggtttcactg
     6541 cgccaaactc agaggcgctg aactgcaggc tttcaccagc gttcacgatg cgtttttgcg
     6601 cgggggcact ggcgagaagc acttccacgg cgtgctgctg cacgtcaagc tgcgtgaaat
     6661 tatcctgctg gcggacggta aattctgtcc ctaaagcagt gagctggccc tgacgggtca
     6721 ggacacggaa ggggcgttgc agggcatctt tcgcggtagt aatggcgatt tcaccgtacc
     6781 agagccggac ggtgcgctga tgcgcatcaa aacgcacatc cgccgcgctt tgggtattca
     6841 gcgtgagcag ggagccatct tccagttgct gacggctgac tgtgcctttg gcggtgcggt
     6901 aatctgcccg cagaccttcg ccggtttccg actgccagag ctgccagcct ccgctagcgc
     6961 cgagcaacag cagtaatcct ttcatcacgt gacggcgggt gaggcgggta tcgtgcaacg
     7021 cccggctggc aacgtcgcca ggcacaccgc caagctggtt gcgcaggttt tcaacctgct
     7081 gccaggccca ctggttatcc tgatcctgtt cataccactg ttgccagcgc gcttcctgtt
     7141 gtgggctgac gcgctcgccg cttagcacgg cataccagtg ggaagctgaa cgcagcgcct
     7201 gacggcggga atcggttaac aaaggattca taacccatac tccagacgga acagcaggca
     7261 gtgctcgacg gctttcgcca cgtatttttt cacggagctg atggaaacac cgagtttgtg
     7321 cgcaatctcg ctgtatgtca gaccatccag ttgcgaaagc agaaacgctt cacgtgtttt
     7381 gccgtttagc ccgtccagca tgctgtcgag gagttgtagg gtctcgagtt ggctttcgcg
     7441 ttcctcaggt gaaggcgctc ccccctccgg cataagcgcc agcatctcca gatacgcttt
     7501 ttccagcgcg tttcggcgaa acaggtccac catcacgcgt ttggcgatag tgcacaggaa
     7561 ggagcgagga tcgcggatcg tcgagagcgt ttcgctgacc attacccgca aaaaagtgtc
     7621 ctgggcaatg tcatctgcat caaaagcaga ctggagtttg cgcgtcagcc agcttttcaa
     7681 ccagccgtga tgtgtgccat aaagcgactc gaacgttaag gaagctgtgg tagtggcgcg
     7741 gtcagacatg cggagtgcat caaaagttaa ttatcacgta gccatattaa tatgagaatg
     7801 gttatcatta caattggaaa taaaattgtt tccaatagac atttttaaca tgttgttttt
     7861 ctaagtgtta tagggtaggt ataaaatggg atggagcctc tgcttctggc atgtgtcggt
     7921 caaaatgact catgatgtgg tctgctatta ttgacattct cactgcccta aaggatgggg
     7981 atttcggtaa tgctgccaac ttactgattt agtgtatgat ggtgatttta aggtgcttgc
     8041 gtggcttcca tttccatcag atgtccttcc tgctccgcta ctgaaggcgt ggtgcgtaac
     8101 ggcaaaagca ctgccggaca tcagcgctat ctctgctctc attgccgtaa aacatggcaa
     8161 ctacagttca cttacaccgc ctctcagccc ggtaagcacc agaaaatcat tgatatggcc
     8221 atgaatggcg tcggatgtcg cgccagtgca cgcattatgg gcgttggcct caacacggtt
     8281 ttacgtcact taaaaaactc aggccgcagt cggtaacctc gcgcatacaa ccgggcagtg
     8341 atgtgattgt ctgcgctgaa atggacgaac agtggggcta cgtcggtgct aaatcacgtc
     8401 agcgctggct gttttacgcg tatgacagga tacggaggac ggttgtggcg cacgtcttcg
     8461 gtgaacgcac tctggccaca ctggagcgta ttctgagcct gctgtcggcc tttgaggtcg
     8521 tggtatagat gacggatggc tggccgctgt atgaatcacg cctgaaggga aagctgcacg
     8581 ttatcagcaa gcgttacact cagcgcattg agcgacataa tctgagacaa catctggcaa
     8641 ggctgggacg gaagtcactg tcgttctcaa aatcggtgga gctgcatgac aaggtcatcg
     8701 ggcattatct gaacataaaa cactatcaat aagttggagt cattacctgg tttttgatgc
     8761 cagccataac gtgtttgact acaaagtatt acgaaagaac tttaatgagc ccctggaata
     8821 attcattaaa gtaatttact tcgctatcct ttttccagtt actcacaaag aaaaatattc
     8881 agaaaataat tcccgggcta gctgcccggg atgattacta ttttaatgga ttgttaatct
     8941 ttgcatattc aaacgggctg atacattgtt ctctgttcgc atccagaaaa tctgcccacc
     9001 actgtagcat aagtcgacgt tcttccagat gttcggcttt atggatatac gcagcacgta
     9061 caccattacg ctcctgatgg ctcatctggc gttccacagc atcgcgggac cacaaacctg
     9121 attctattaa tgcactacat gccatcgccc ggaatccatg accacagaca tcctgggttg
     9181 tgtcataccc cataaccctc agggctttat ttacggtgtt ttcactgatt ggtttacgtg
     9241 ggtcatgtgc tcccgtaaag atcagaccat tttcacctgc ccatgtctga agttctgcca
     9301 gtatggctac agcctgttgg ctgagtggca caagatgtgg tgttcgcatc ttggagcccc
     9361 ggtatgaaaa ttttacgcct ggcagaggtt cgcgttcggc tggaatagtc cacatggcat
     9421 tgtcaatatc aatttcagac cagcgggcat atctgagttc actggaacga ataaaaacca
     9481 gtaaattcag cataactgcc agtcgggtga caggctggcc tttataaccg tcaatacgcg
     9541 acagaagttc aggcaggcgt gaaagatcca gagcagggcg atgctggcgt tttaccgtgg
     9601 tcaatgcacc agccatatcc agagccgggt tatatctgat gatgccagac tgtacggcat
     9661 aacgcattac a
//
LOCUS       DAZUDJ010000122         9379 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.124, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000122 DAZUDJ010000000
VERSION     DAZUDJ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9379
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.124"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(41..826)
                     /locus_tag="ACHY1N_004652"
     CDS             complement(41..826)
                     /locus_tag="ACHY1N_004652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046824.1"
                     /translation="MNSKKLCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTP
                     QQLTDKDLFGNETTLAVSEEDIQAALDGDEFRVPLNSPVILVQSGNRAPETIMQEEMR
                     KYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVASAENMNWMQALRFVAAKGHQKAIIV
                     FQDTLQTGKYDSALKSTVWSDYKNEKLTDAISLRYLVRFTLVDVATGEWATWSPVNYE
                     YKVLPPLPDKNEASTTDMTEQQIMQLKQKTYKAMVKDLVNRYQ"
     gene            complement(1158..1234)
                     /locus_tag="ACHY1N_004653"
     tRNA            complement(1158..1234)
                     /locus_tag="ACHY1N_004653"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1198..1200),aa:Asp,seq:gtc)
     gene            complement(1367..2098)
                     /gene="dnaQ"
                     /locus_tag="ACHY1N_004654"
     CDS             complement(1367..2098)
                     /gene="dnaQ"
                     /locus_tag="ACHY1N_004654"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HFS4046825.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRIVRQASKLRVVFAT
                     DEELAAHEARLDLVEKKGGSCLWRA"
     gene            2163..2630
                     /gene="rnhA"
                     /locus_tag="ACHY1N_004655"
     CDS             2163..2630
                     /gene="rnhA"
                     /locus_tag="ACHY1N_004655"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HFS4046826.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHSWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     gene            complement(2627..3349)
                     /locus_tag="ACHY1N_004656"
     CDS             complement(2627..3349)
                     /locus_tag="ACHY1N_004656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414749.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4046827.1"
                     /translation="MKPARVPQTVVAPDCWGDLPWGELYRKALERQFNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISLMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQYRKPQA"
     gene            3383..4138
                     /gene="gloB"
                     /locus_tag="ACHY1N_004657"
     CDS             3383..4138
                     /gene="gloB"
                     /locus_tag="ACHY1N_004657"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004416 - hydroxyacylglutathione hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019243 - methylglyoxal catabolic process
                     to D-lactate via S-lactoyl-glutathione [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HFS4046828.1"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAITANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLNKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
     gene            4210..5568
                     /gene="mltD"
                     /locus_tag="ACHY1N_004658"
     CDS             4210..5568
                     /gene="mltD"
                     /locus_tag="ACHY1N_004658"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008933 - lytic transglycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HFS4046829.1"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSSVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     gene            complement(5616..6386)
                     /locus_tag="ACHY1N_004659"
     CDS             complement(5616..6386)
                     /locus_tag="ACHY1N_004659"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4046830.1"
                     /translation="MTTQSHHDHVEKQFSSQASEYLTSTVHASGRDLQRLAVCLADYP
                     DASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAE
                     SLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRMIVMDVMSPGHPVRDIWL
                     QTVEALRDTSHVRNYASGEWLRLINEANLIVDNLITDKLPLEFSSWVARMRTLEALVD
                     AIRIYQQSASTEVRTYFALQNDGSFTSDIIMVEAHKAA"
     gene            complement(6464..7264)
                     /locus_tag="ACHY1N_004660"
     CDS             complement(6464..7264)
                     /locus_tag="ACHY1N_004660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFS4046831.1"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     gene            7505..8419
                     /gene="yafC"
                     /locus_tag="ACHY1N_004661"
     CDS             7505..8419
                     /gene="yafC"
                     /locus_tag="ACHY1N_004661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YafC"
                     /protein_id="HFS4046832.1"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMASAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHICLGFTEPASLNTWPIARSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELMADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     gene            complement(8416..9219)
                     /gene="dkgB"
                     /locus_tag="ACHY1N_004662"
     CDS             complement(8416..9219)
                     /gene="dkgB"
                     /locus_tag="ACHY1N_004662"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047834 - D-threo-aldose 1-dehydrogenase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HFS4046833.1"
                     /translation="MAIPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAA
                     VGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKTIAAVGAENIATNQIELSPYLQ
                     NRKVVVWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRENLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
BASE COUNT         2529 a         2212 c         2214 g         2424 t
ORIGIN      
        1 attattgccg ccagaaattc ctggcggcag atataattta ttattgatag cggttaacca
       61 aatcttttac catcgcttta taggtctttt gcttaagttg catgatttgc tgctctgtca
      121 tatcagtcgt actggcttca ttcttgtcgg gcaatggtgg aagcacttta tattcataat
      181 tcaccggcga ccaggtagcc cactcacctg ttgccacatc caccagcgtg aaacgtacca
      241 ggtagcgcag ggagatagcg tcggtgagtt tttcattttt atagtcggac catactgttg
      301 atttcagcgc agagtcatat tttcctgtct gcaacgtatc ctggaaaaca ataatcgctt
      361 tctgatgccc ttttgcagcc acaaaacgca gtgcctgcat ccagttcata ttctcagcac
      421 tggcaacatc ctcgttctca tttttatctt tgtttttgtt acaagtcaga ggcttttgcc
      481 tgtccgggat accagagaat gtggaaacag tataatattt tcgcatctcc tcctgcataa
      541 tggtttccgg tgcgcggttg ccggattgaa caagtattac aggagaatta aggggaacgc
      601 ggaactcatc tccatcaagc gcagcttgaa tatcctcttc ggatacggcc agagtggttt
      661 cattaccgaa taaatctttg tctgtcagtt gctggggagt gtttttatta atattacttt
      721 gtgtgacttg agcttttttc ttcttttcat caatagaaga ttcagaggca catcctgcaa
      781 gcagcgagaa taacacacat atgcaacaaa gcttttttga attcataatt ggacactccc
      841 tcgcctgtca taatcatggt aatgtttagc taacgatttt taattatata ctccacttga
      901 atcagaacaa acaaaaataa cagtatatat aaattcatta aatcaataga aaaatgaaaa
      961 tcataacatt caaatatatt taaattgaat gattcgatag tatgattaaa tattaatgat
     1021 atggtctacc atatgtgatt aacacattta cagcataaca aaaccataga ccgaagaaat
     1081 agcgggattt aaatgcaaaa aaaaaccgca aaattaaaaa tcttgcggtt ctctgaactc
     1141 attttcatga gtgaatttgg cggaacggac gggactcgaa cccgcgaccc cctgcgtgac
     1201 aggcaggtat tctaaccgac tgaactaccg ctccgcgttg tgttccgttg ggaacgaggc
     1261 gaatattacg gattgcctca cccttcgtca acggtttttc tcatcttttg aatcgtttgc
     1321 tgcaaaaatc gcccaagccg ctattttcag cgccttttac aggtatttat gcccgccaga
     1381 ggcagcttcc gcccttcttc tccaccagat caagacgggc ttcatgagct gcaagctctt
     1441 catctgtcgc aaaaacaacg cgtaacttac ttgcctgacg tacaatgcgc tgaattgttg
     1501 cttcaccttg ttgctgctgt gtctctcctt ccatcgcaaa agccatcgac gtttgaccac
     1561 cggtcatcgc cagataaact tccgcaagga tctgtgcatc gagtaatgcc ccgtgtagcg
     1621 ttcgtttact gttatctatt tcgtagcggg cacataacgc atcgaggctg ttgcgcttac
     1681 caggaaacat tttcctcgcc accgcaaggc tatcggtgac cttacagaag gtattggtct
     1741 tcggaatatc gcgcttaagc aacgaaaact cgtagtccat aaagccgata tcgaacgctg
     1801 cgttatggat caccaactcc gcgccgcgga tatagtccat gaactcatcg gctacttcgg
     1861 caaacgtggg cttatcgagc aaaaattcat cggcaatacc atgtacgcca aaggcttccg
     1921 gatccaccag ccgatcgggt ttgagataaa catggaagtt attgcccgtc aggcgacggt
     1981 tcaccacttc aacggcacca atctcaatga tcttgtggcc ttcatagtgc gcaccaatct
     2041 ggttcatacc ggtggtttcg gtatcgagaa cgatctggcg tgtaattgca gtgctcatag
     2101 cggtcattta tgtcagactt atcgttttac agttcgattc aattacagga agtctaccag
     2161 agatgcttaa acaggtagaa attttcaccg atggttcgtg tctgggcaat ccaggacctg
     2221 ggggttacgg cgctatttta cgctatcgcg gacgcgagaa aacctttagc gcaggctaca
     2281 cccgcaccac caacaaccgt atggagttga tggccgctat tgtcgcgctg gaggcgttaa
     2341 aagaacattg cgaagtcatt ttgagtaccg acagccagta tgtccgccag gggatcactc
     2401 agtggatcca tagctggaaa aaacgtggct ggaaaaccgc agacaaaaaa ccagtaaaaa
     2461 atgtcgatct ctggcaacgt cttgatgctg cattggggca gcatcaaatc aaatgggaat
     2521 gggttaaagg ccatgccgga cacccggaaa acgaacgctg tgatgaactg gcccgtgctg
     2581 cggcaatgaa tcccacactg gaagatacag gctatcaagt cgaagtttaa gcctgtggtt
     2641 tacgatattg ccgggtggct ccaaccgcct ggcgaattcg tggcttgttt ttactctgtt
     2701 tcatcggatt tagcgttaaa ggaatagtcc gtttccgggc aacaataagt tgtaagcaac
     2761 caagcgcagg aatatgtgca ttcaatagtt ttccaccgtg tttgttccac gggagaacgt
     2821 ggaaacggct ggcgtgcagc acttcaaaat tcaacaaaga gagccagtcc agttgccgca
     2881 tcagagtaaa catccggctg ttatagggcg aggttttgcg caataccggc acaagtttgc
     2941 gtaatcccat taaactgatg ggattgaagc cactaatcac cagccagcca tcatcaatca
     3001 atacccgatc ggcttcacgc aataaacgat gcggatcggt gcaccacggc aatgtatgtg
     3061 ccagtagaca aacatcaacg gatttatcgg caaaaggaag atgaagtggg tccgcctgta
     3121 cctggacggg cattccttgc gcagaaacat tcacttgatg agaaaccgcg cacgcttcgc
     3181 aattgatttc tgcgcttaaa ttgccaatct taagcagatg aaaaccatac attttagtga
     3241 accacgggtt gaactggcgc tccagcgcct tgcgataaag ctctccccag ggcaaatcgc
     3301 cccagcaatc aggagccacg acagtttgag ggactcttgc cggtttcatc acaaccttcc
     3361 gtttcacact aagaggtaat ctatgaatct taacagtatt cccgcctttg atgacaatta
     3421 catctgggtt ttgaatgatg aagcaggtcg ctgcctgatt gtcgatcccg gagacgcaga
     3481 gccagtatta aacgccatta ccgccaataa ctggcaaccg gaggccatat ttctcaccca
     3541 ccatcatcac gatcacgttg gcggcgtaaa agaactggtg gaaaagtttc cgcaaattgt
     3601 ggtgtatggt ccacaagaga cacaagataa gggaacaaca caggtagtca aagatggcga
     3661 aactgccttc gttttggggc atgaatttag tgtaattgcc acaccgggtc acactttagg
     3721 acatatctgt tacttcagta aaccttatct attttgcggc gacacgctgt tttctggtgg
     3781 gtgtggtagg ttgtttgaag ggacagcatc acaaatgtat caatcactta ataagttaag
     3841 tgcgttacct gacgatacat tggtatgttg tgctcatgaa tatacgttat caaatatgaa
     3901 gtttgctttg agtattcttc cgcacgattt gtccataaat gattattatc gtaaagttaa
     3961 ggagttacgg gcaaaaaatc aaataacact acccgtaatt ctgaaaaatg agcggcaaat
     4021 taatgttttt ttaagaacag aagatattga tttaattaat gtaattaatg aagaaacatt
     4081 attgcaacaa cctgaagaac gttttgcatg gttaaggtca aagaaagata ggttctgata
     4141 aaactttctt gtcatcggct ccgttcgccg ttatgatcgg tcgtctttta agcaactatt
     4201 gacacacaca tgaaggcaaa agcgatatta ctcgcctctg tcctgctcgt gggttgccag
     4261 agtaccggca acgttcaaca gcacgcacag agcctttctg cagctggtca aggggaagca
     4321 gcaaagttta caagtcaggc acgatggatg gacgatggga cgtctatcgc gccagatggt
     4381 gacttgtggg ctttcattgg cgacgagcta aagatgggaa ttccggaaaa tgaccggatt
     4441 cgcgaacaga aacagaaata tttacgcaat aagagctatc tccacgatgt aactttacgg
     4501 gcagagccgt atatgtactg gatagccggg caagttaaaa aacgtaacat gcctatggaa
     4561 ctggtactac tacccatagt ggagagcgct tttgatcctc acgcaacgtc tggcgccaat
     4621 gccgcaggca tctggcagat cattccgagc acggggcgca attatggttt gaaacagacc
     4681 cgcaattatg acgcgcgtcg cgatgttgtt gcttcaacaa ctgccgcgct gaacatgatg
     4741 cagcgtctga acaagatgtt tgacggcgac tggcttctga ccgtagcggc ttataacagc
     4801 ggcgaaggtc gggtcatgaa ggcaattaaa acgaacaaag cgcgtgggaa atccacggac
     4861 ttctggtcgt taccgttgcc gcaggaaacg aagcagtacg tgcctaaaat gctggcattg
     4921 agtgatattc tcaaaaacag caagcgttat ggcgtacgtc tgccaacgac cgatgaaagc
     4981 cgtgctctgg cgcgtgtgca cctgagcagc ccggttgaaa tggcgaaggt tgcagatatg
     5041 gcggggattt ccgtcagcaa gctgaagaca ttcaacgctg gcgtgaaagg ctccacgctg
     5101 ggcgcaagtg gtccgcaata cgtgatggtg ccaaagaagc atgcagatca actgcgtgaa
     5161 tctctcgctt caggcgaaat tgctgctgta cagtcgacgc tggttgccga caatacgccg
     5221 cttaacagca gtgtttacac cgtacgctct ggcgacacgc tttcaagtat cgcttcacgt
     5281 ctcggcgtaa gcaccaaaga tttgcagcag tggaacaaac tgcgcggatc taagctgaag
     5341 ccaggccaaa gtttgacgat tggtgcaggc agtagcgcac agcgactggc aaacaacagc
     5401 gatagcatta cgtatcgtgt gcgcaaaggc gattcgcttt caagcattgc taaacgccac
     5461 ggcgtgaaca tcaaagatgt gatgcgctgg aacagcgaca ctgcgaatct gcaaccaggc
     5521 gacaagctga cgttgtttgt gaaaaacaac aacatgccag attcctgaca aaccagataa
     5581 taaaaaggca ccgattcccc cggtgccttt tttatttatg ctgctttatg tgcttctacc
     5641 atgatgatat cactggtgaa agagccatca ttctgcaagg caaaatacgt tctcacctct
     5701 gtcgatgcgc tctgttggta aatgcgaata gcgtctacta acgcttctag cgtacgcatt
     5761 ctcgcgaccc atgaagaaaa ttccagcggt aacttatctg taattaaatt atcaactatc
     5821 agattggctt cattgattaa cctcaaccac tcaccgctgg cgtagtttcg tacgtgagag
     5881 gtatcgcgta atgcttctac cgtctgtaac cagatgtcgc gcactggatg acccggagac
     5941 attacgtcca tcacaatcat cctaccgcca ggtttcaata tcctattcac ttctcgcagt
     6001 gctgcaccaa catcatgcca gtgatgggca gaataacggc tgataacaat atcaaatgcg
     6061 ttatcggcaa atggcagact ttcggcataa ccctggcggg tggtgatatt tttcagttgc
     6121 cgggcttcgg cagcttgtgc cacgacatcc agcatttggg cagataagtc atacgccacc
     6181 accgcgctca cgttctgcgc agcgacaaag ctggcatgcc ctgctccgca gcccatatca
     6241 agtacacttg catcaggata atcagccaga cacaccgcca ggcgctgtaa atctcgcccg
     6301 gatgcatgta cggtactggt taaatactca ctggcctgcg agctaaactg cttttctacg
     6361 tggtcatggt gggattgtgt tgtcattgcg ctgtcctttt gttgtttgag tataaaagga
     6421 cagcgccaaa cgttggtctg ccctgtggca gacctgacat accttattta tcaggcttgc
     6481 cgggactgaa ttcaacgagt agcggattgt gatcggaagc gcgcgtaacc aatacagaag
     6541 cttcgctgac gttcagacca cggtagaaaa caaaatcgag cgggcggcca aacgcccgac
     6601 ggcgctgatc atcggtaaaa cgcacctggc gcagcgacat ttcccgcgca aagcgatata
     6661 acgcgttcat ccttctacgg ctccaggcat tgaaatctcc tgccataatg accgggccgc
     6721 tgtggtgagc tatctgatca ccaataggaa gtaactgctt actatagaca tccacgccca
     6781 gactgaagtt gacggcgtgt atattaacca ccatcaacag gcgggtgtca ggtaatggat
     6841 agaccgtcac cagtgccgac ttcgccagac gcaaaatggg ttctcgttca cgtaacgggc
     6901 agcaatacac tggatgcgcc gccgaaaggg tcattacgcc agaaggatgt tgtggcagta
     6961 cgaaagcggg tacctgatcg gcggcaagat agttagcggt cgcaaactgt actaactctg
     7021 gcgttgtctg cgcttcctgc aataacacca gatgtgcatc tttgccgtag ttctttaata
     7081 ccgacaacca ttcagcgcgt tgctgtttgt atatgttcca caccaggatc cgaatacgct
     7141 cttcggtact taacggttct ccgggtggta atgcctggcc gatgctcgca aaagaccccg
     7201 gcggtaagat cctttccgca ggttgtccgg caacatagcg catggcatag gtgttttttc
     7261 gcacttttga ctttgaaacc tctattacgt caacccttcc gcactcggga gggttctact
     7321 gttataggga ttttagctca ctctttcaac gagcaattgt atattgttat gtaagcaagt
     7381 gcttacaccg gtcagaattt tgctcattat ggagaacatt aaatcgcatg acatatcacg
     7441 catcctgatg gtttaatgac aaataaattc aaaatatctc ttctattttg caacaggagc
     7501 aaaaatgaaa gccacgtcgg aagaactcgc catttttgtt tcggtcgtcg aaagcggcag
     7561 ctttagccgg gcagcggaac aattagggca agcaaactca gcggtaagcc gggcggtgaa
     7621 aaagctggag atgaaacttg gcgttagcct gcttaatcgg accacgcgac aacttagcct
     7681 gacggaagaa ggcgagcgtt attttcgtcg cgtacagtca attttgcagg agatggcatc
     7741 ggcagaatca gaaattatgg agacgcgtaa tacaccgcgt ggactgttac ggatcgatgc
     7801 cgcaactcca gtggtgctgc actttctgat gccgttaatt aagcctttcc gtgaacgcta
     7861 tccggaagtc actttgtcgc tagtctcctc cgaaacgatt attaatttga tcgaaagaaa
     7921 agtggatgtc gcgatacgcg ctggtacgtt aacggattcc agcttacgtg ccaggccgtt
     7981 atttaacagt tatcgaaaaa ttatcgcctc ccccgattat atttcccgct acgggaagcc
     8041 agaaacgatc gacgatttaa agcaacatat ttgcctggga ttcactgaac ccgcttccct
     8101 caatacctgg ccgatagccc gtagcgatgg acaattacat gaggtgaagt acggtttgtc
     8161 atccaatagt ggggaaacac tgaaacagct ttgcctgagt ggcaacggga ttgcgtgttt
     8221 gtccgactac atgatcgaca aagaaatcgc tcgcggagaa ttggtggagt taatggcaga
     8281 taaagtgttg ccagtggaaa tgccattcag tgcagtctat tacagcgacc gtgcggtaag
     8341 tacgcgcatc cgggctttta tcgatttcct tagcgagcat gtaaaaacag ctcccggagg
     8401 agctgtcaga gaggcttaat cccattcagg agccagacct tccgggctaa ccaggcggtc
     8461 gttgcaatcc agtgcggcga tcgctttttt atcttcggca tcaagctgta aattttgtgc
     8521 cttaagatta ctttccaggt tttcacgttt agtagaagaa ggaattactg agtaaccttc
     8581 ccccatagcc cacgccagaa tcacttgtgc cggagtcgca ttgtgtttag ctgcgatacg
     8641 agcaataacc tcatctttca gggccttacc atacgccagc gtcatatagg aagtaatatg
     8701 gatgccgtgc tgtttagccc agacaaccac tttacggttt tgcagataag gagagagttc
     8761 aatctggtta gtagcgatgt tttcagcgcc aacagcagca atcgtttttt ccatcaacgg
     8821 gatcgtgaag ttggaaatac cgatctcacg tgtcagacct tgttttttgg cttccagcag
     8881 cgcctgcata aactcttcaa cagagacttc atcgtttggt gacggccagt ggattagcgt
     8941 cagatcaaca taatcggtac gcaatttttg caggctctct ttcagacttg ggatcaattt
     9001 gtctttgctg agattttcaa tccagatttt agtggtgatg tagagttcat gacgtggcac
     9061 gccactttct gcaatcgcct gacctactgc ggcttcgtta tcatagattt gtgcggtatc
     9121 aattgcgcga taaccaagtt caagcgccgt tttcacagat gaaataacaa cgtcgtcttt
     9181 cagacggaaa gtacctaaac caaatgcagg gatagccata atatgcctct tttaatgcta
     9241 ttttcgttaa ctgaggtgat tatgggcttc agactgttgc ggaaaaagag cgtaaaacgc
     9301 agaggatttt tgcgattctg gcaataatag aaatgtagac gaaaaaaaac ctcgagcgat
     9361 aactcgaggc ttcttaata
//
LOCUS       DAZUDJ010000123         9044 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.125, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000123 DAZUDJ010000000
VERSION     DAZUDJ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9044
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.125"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..164)
                     /locus_tag="ACHY1N_004663"
     CDS             complement(<1..164)
                     /locus_tag="ACHY1N_004663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HFS4046834.1"
                     /translation="MRLASRFGYTNQIRRERPLTHEELMHYVPSIFGEDRHTSRSERY
                     AYIPTITVLE"
     gene            complement(254..328)
                     /locus_tag="ACHY1N_004664"
                     /pseudo
     CDS             complement(254..328)
                     /locus_tag="ACHY1N_004664"
                     /inference="COORDINATES: protein motif:HMM:NF017787.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            296..435
                     /locus_tag="ACHY1N_004665"
                     /pseudo
     CDS             296..435
                     /locus_tag="ACHY1N_004665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001367567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(575..988)
                     /locus_tag="ACHY1N_004666"
     CDS             complement(575..988)
                     /locus_tag="ACHY1N_004666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046835.1"
                     /translation="MKNIITILMIAVISFFTANVSANNAVPLPTNLTDVTDGTEFWCQ
                     GTDTIDGGCEYLGTSKDMQYGLVHAMGGTACWDGLYGVINFYTGKAQTIKFNNNQSCE
                     GNITAGFVTLKNGKPGVKLYDNTIHKIVGLDEIKI"
     gene            complement(1258..1797)
                     /locus_tag="ACHY1N_004667"
     CDS             complement(1258..1797)
                     /locus_tag="ACHY1N_004667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4339 domain-containing protein"
                     /protein_id="HFS4046836.1"
                     /translation="MNWHYEKNGVRYDNVTEEDIIERIRRGELNASTLVWQQGMLEWQ
                     PVSATSLAEILKQSEVPPALPGHRIPGGVVWTLAFAPLIGYILEMWTAGLNGMSFERA
                     YDAVSEGQYWFISLILNIALGYLDERKLRKSGVDTATFGWLAWLIPVYLWRRAKILGQ
                     KPAYFWVWLVMLILVLFTI"
     gene            complement(1923..2096)
                     /locus_tag="ACHY1N_004668"
     CDS             complement(1923..2096)
                     /locus_tag="ACHY1N_004668"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046837.1"
                     /translation="MNKNAWVYFIDAIGEATKLDVLVNGKKVDSYTANIKNEKKTLGN
                     KFYGSCRNTWFQE"
     gene            complement(2512..3582)
                     /locus_tag="ACHY1N_004669"
     CDS             complement(2512..3582)
                     /locus_tag="ACHY1N_004669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFS4046838.1"
                     /translation="MSTEMKTGLVLSGGGAVGAYQAGVVKALAECGSQISMVSGASIG
                     AFNGAIIAASPDLSEAAVRLEALWDHLGNNQVLSVNRSVYFSLLKKLFQAMNLCQIPG
                     HAGALLTTLFRHISIINGFDNPMTQPLLSDEPLTALMDHYLDTDALADGLPLYVSLYP
                     TEGGMQDIIDCIRAELGVGTTKNAVFQHIQSLPRGQQKEALLASAALPLLFRPREVQG
                     TMFGDGGMGGWRNMQGNTPVTPLVDAGCNMVIVTHLSDGSLWDRQAFPDTTILEIRPR
                     KRLKHAGDGGNSGGLLSFTSAHIDAWRQQGYEDTMLTMEHIRKPLAARQALTRSEAVL
                     QKSQEITEGADSALRNAMAQIK"
     gene            complement(3579..4484)
                     /locus_tag="ACHY1N_004670"
     CDS             complement(3579..4484)
                     /locus_tag="ACHY1N_004670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase regulator RdcB family
                     protein"
                     /protein_id="HFS4046839.1"
                     /translation="MTSPFIQQIADNRVCQVLTCLPEKFVVDFANGIDVAQEHIRTAG
                     ERTFFRRLKEGLTGEGAARQNAINASLAQGVEASLRWLTEMTTSLATTNYAITRVNDR
                     VSSLVSDTARLAHYSADTREQLLTLADQVHQKLNHLEEKLHRVDQVQRAQLHLEQIFS
                     WWSAGRYASFSPAGRCYVVLEELRWGAFGDVIRQGETGQVNQLLDILRHKALTQMAQE
                     SGGSATVRLNTLDWLGGQGREQADNEWHDAINWLGDWCSEERHPVIWSTTQAAEHLPV
                     RMPRLCSAERLSESMVDEIFQKGAA"
     gene            complement(4481..6865)
                     /locus_tag="ACHY1N_004671"
     CDS             complement(4481..6865)
                     /locus_tag="ACHY1N_004671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HFS4046840.1"
                     /translation="MHEKNIALLCDEADRLLQLNINLLRQMVDEPDVLSDSKNENGLL
                     FDKQKALKRIEELEGEQIKTARREMVLAVVGTMKAGKSTTINAIVGQEILPNRNRPMT
                     SVPTLIRHVPGKTEPVLHLEHTQPVRNLLITLQEKLATPAGQQVAQTLQQTGDTRELL
                     DILTDDGWLKNEYHGEEEIFTGLASLNDLVRLAAAMGSDFPFDEYAEVQKLPVIDVEF
                     SHLVGMDACQGTLTLLDTPGPNEAGQPQMEVMMRDQLQKASAVLAVMDYTQMNSKADE
                     DVRKELNAIADVSAGRLFVLVNKFDEKDRNGDGADAVRQKVPAMLNSDVLPASRVYPG
                     SSRQAYLANRALHELRKNGTLPVDEAWVDDFVREAFGRMKKDYVCKDSELATEGATDL
                     WEGSLIDQLITEVIQSSHSRAAALAVDSAAAKLMQNAENVSEYLSLRHQGLQQSIQSL
                     QAHITSLLADIQEIEECQNQVTGDVRMAMEDINTKTGELLTKVCASLEEELNDYFRSG
                     KRKEQQMLEEENSAQPRERNAFAFFHDIFGTGNQHDRMRDFDPDSPEIKFSDRRAALE
                     LMTQIESTVTSLHREAEAQFRPELEKIVRGIETGFRGTALYATEKIAGRINARLEDEG
                     FTVKISFPAVSQLQTRLAVQTNLSALMEERTETVTRRRRQDGVWGTLCRWANTSDWGW
                     KEYSVDVSRSVINMNKVRKEVMSLTRAYFGELQASIEQNINQPVRQEIDDFFCTFREK
                     VEQLRNTLIQSSEDHKRDQQAQEHLTERLQALNERVPELITDSKALREELETML"
     gene            complement(7052..7896)
                     /locus_tag="ACHY1N_004672"
                     /pseudo
     CDS             complement(7052..7896)
                     /locus_tag="ACHY1N_004672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
     gene            8220..8807
                     /locus_tag="ACHY1N_004673"
     CDS             8220..8807
                     /locus_tag="ACHY1N_004673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046841.1"
                     /translation="MGLDDFGLSILAGLLANRLDFSKPKGTSAQMNEVIPDVIEEPDK
                     FSLSANLPKRFKTFDVWSDLDELLKVVKEPKISVLIEEQPSTYYRLPSLVLESQITGE
                     WYVFPRGRMSFEGNGGGIQNAEVIFNQLKEENVPVGVWVIDQALLDRLDNGQECWPTI
                     RLQIVPFLAAPSSEYPWFEIQRNVAKLTEFHLTND"
BASE COUNT         2252 a         2337 c         2088 g         2367 t
ORIGIN      
        1 ttttccagga cggtgatggt gggaatgtac gcatagcgtt cactgcggga ggtatgccgg
       61 tcttctccaa aaatactggg aacatagtgc atcagctctt catgtgtcag tggacgttca
      121 cggcgtatct ggtttgtata accaaaacga ctggctaatc gcataattgc tccttatgaa
      181 tgattaagcg gtataaatga aaaaaccgcg tctcccggag aagacgcggc ctgatgggtg
      241 aaatgaatga ggtttattgt ccgggaagcc cttcactggt gagccacgca ttaagttgtt
      301 tgcctgcata gggttcagaa ttccggcagc gccagcgtcg ctgaccttcc gcgttgcgga
      361 taatccgccg gaaatgcatt cctggataaa cacattgcgg taagctgtta tgacagcaac
      421 tgtctgtttg cgtgagaaag gatcttcgga aaataaaagt aatgtacagc ccgtcatgta
      481 ttttcaggta aaaataaagc ccctgccatt atggcagagg atttatttac atttgatatt
      541 aataacgcgc agataagata ctataattca tacattaaat tttgatttcg tcaagcccga
      601 caatcttatg aatcgtattg tcgtaaagtt taacgccagg tttaccgttt tttagagtaa
      661 cgaaaccggc ggtgatgttg ccttcacaac tttgattgtt gttgaatttg atagtctggg
      721 ctttaccggt atagaaatta attacgccgt ataaaccatc ccagcacgct gtacccccca
      781 tggcgtgtac cagaccgtat tgcatgtctt tggatgtgcc caggtattca caacctccgt
      841 cgatagtatc agtaccctga caccagaatt ctgtaccgtc agtaacgtca gtcaggttgg
      901 tcggtaaagg aacggcattg tttgctgata cattagcagt aaagaaactg ataactgcaa
      961 tcattaaaat agtgatgata tttttcatga taaatactcc attgtttctg atattaaata
     1021 aaagtataaa aactgtttct gcaatactta taatccactc gagaggtcag gattaacccc
     1081 cgacttgttt attaaacaca tacctgaaga tatgaccttc aacatggtga tatatttata
     1141 ctatgtttct gactgtctcc tgaatcaaat aaaatatatc cgctccatga tgaacatcat
     1201 ttacctgtta agaacactaa taacctgatt atttagcaaa ctctgcgaaa aagaatatca
     1261 gatcgtaaat aacaccagta tcagcataac cagccagacc cagaaataag caggtttttg
     1321 cccgaggatc tttgcccgac gccacagata aaccgggatc aaccatgcca gccagccaaa
     1381 tgttgcagta tcaacaccag atttacggag ttttcgttca tccagatatc ccagagcaat
     1441 attcagaatc agagagataa accagtactg gccttcgctg actgcatcat aagcccgttc
     1501 aaatgacata ccgttcagcc cggcagtcca catctcaagt atgtacccaa tcaaaggggc
     1561 aaatgccagc gtccagacaa cgcctccggg aatgcggtga cccggaaggg ccgggggaac
     1621 ttcactttgt ttcagtattt ccgccagtga tgtggctgaa actggctgcc attccagcat
     1681 gccctgttgc cacaccaatg ttgatgcatt cagttcacca cgccggatac gttcgataat
     1741 atcttcctct gttacgttat cataacgtac accatttttt tcataatgcc agttcatctg
     1801 attctcctgt taatcattta gttaataaaa tatatgacat ctgaaacaaa aaatattttt
     1861 atgatattca ttttcactca ctgtattaaa ttaaactgag gtgttttaca ccacgttatc
     1921 aattattcct ggaaccaggt gttcctgcag ctaccgtaga atttgttacc caaagtcttt
     1981 ttctcatttt tgatatttgc ggtatagctg tcgactttct taccgtttac taaaacgtcg
     2041 agcttcgtgg cttcaccgat agcatcgata aagtataccc acgcattctt attcattcgt
     2101 gttccgtcga caggtggggc cgaatacttt ttaccgttga tgataaaaat aatatcagaa
     2161 tcgtactgat ttagcggggt gggggtatga ccgtaaatcc actcatatgt ggtagcaaat
     2221 tgttgtcttc tggattaatc gtgcagttaa tagaaacact accgatactg aacatatcag
     2281 tgccagcaac actgttacgc ttctacaatg ccgattctgc ttgtgctacg gttgtactta
     2341 cagttaaaac aacagctaaa agaatgttta acagtttcat gagatttctc cccaaaatta
     2401 aataaattaa tcttaaccat catccaggta atatatatct gaaaatattt tcaataacac
     2461 cagataagaa aaacaccacc acagtggcgg tggcgtttct ccggtgtgtc tttatttaat
     2521 ctgggccatc gcgtttctca gtgccgaatc tgcaccttca gttatctcct ggcttttctg
     2581 taataccgcc tctgacctgg tcagtgcctg acgcgccgcc agtggtttcc ggatatgctc
     2641 catcgtcagc atcgtgtcct cgtagccctg ctgacgccag gcgtcgatat gtgccgacgt
     2701 gaaactgagc agaccgccac tgttgccacc atcacctgca tgtttcagcc ttttccgggg
     2761 acggatctca aggattgtgg tgtccggaaa agcctggcga tcccataaag aaccgtcact
     2821 cagatgcgtc acaatcacca tattgcatcc ggcatcgacc agaggcgtta caggggtatt
     2881 tccctgcata tttcgccatc ctcccatacc accatcaccg aacattgtcc cctgaacctc
     2941 acggggacgg aacaacaggg gcagcgcggc tgacgcaagc agagcctctt tctgctgtcc
     3001 gcggggcaga ctctggatat gctgaaaaac ggcgtttttc gtggttccga cacccagttc
     3061 agcacgaata cagtcaataa tatcctgcat gcccccttct gtggggtaca gcgacacata
     3121 cagcggtagc ccgtctgcca gagcatcagt atcaagataa tgatccatca gcgctgtcag
     3181 gggctcatct gacaacaacg gttgagtcat cggattgtcg aacccgttga ttatcgatat
     3241 atggcgaaaa agcgtcgtaa gcagtgcgcc cgcatgtccg gggatctggc agaggttcat
     3301 tgcctggaac aattttttca gcaatgaaaa gtaaaccgat ctgtttaccg acagcacctg
     3361 attattcccc agatgatccc agagcgcctc caggcgtacg gcagcttctg acagatcggg
     3421 agaggccgcg ataatggcac cattgaatgc gccaatgctg gcccctgaaa ccatgctgat
     3481 ctgtgaacca cactctgcca gtgccttaac cactcccgcc tgataagcgc ccaccgcccc
     3541 gccgccggac agcaccagcc ccgttttcat ttctgtactc atgcagcccc cttctgaaat
     3601 atctcatcga ccatactttc agagaggcgt tctgcagagc agagacgggg catgcgaact
     3661 ggtaagtgtt ctgcagcctg cgtggtcgac cagatcaccg gatgccgctc ttcactgcac
     3721 cagtccccca gccagttaat cgcgtcatgc cactcgttat ctgcctgctc ccggccctga
     3781 ccaccaagcc agtccagagt gttcagacgc acggttgcac taccgccact ctcctgtgcc
     3841 atctgcgtta atgctttatg tctgagaata tccagtaact ggttaacctg gcctgtttca
     3901 ccctgacgta tcacatcacc aaacgcgccc cagcgaagct cttcaagcac cacataacag
     3961 cgtccggcag gggaaaatga cgcgtatcgc ccggcgctcc accatgagaa tatctgctca
     4021 agatgtaact gtgcccgctg aacctggtca acacggtgga gtttttcttc aagatgattc
     4081 agtttctggt gaacctgatc ggccagggtg agtaactgct cccgcgtgtc tgccgaataa
     4141 tgcgccagcc tggcagtatc actgaccagt gaactgaccc tgtcgtttac ccgggtaatt
     4201 gcgtagtttg tggtggcaag tgacgttgtc atctccgtca gccagcgcag ggacgcctca
     4261 acgccctgtg caagcgaagc attgatggca ttctgccgtg cagcgccttc gccggtcagc
     4321 ccctctttta aacgccggaa gaacgtgcgc tctccggccg tgcggatatg ctcctgtgca
     4381 acatcgatac cgtttgcaaa atcaaccaca aatttttcag gaaggcaggt gagtacctga
     4441 catacccggt tatcagcaat ttgttgaata aatggtgaag tcacagcatt gtctccagct
     4501 cttcccttaa cgccttactg tcagtaatca gctcgggaac cctttcattt aatgcctgaa
     4561 ggcgctccgt aagatgctcc tgtgcctgct gatcgcgttt atgatcttct gagctctgaa
     4621 tgagtgtgtt acgtagctgt tcgacttttt ccctgaatgt acagaaaaaa tcatcgatct
     4681 cctggcggac gggctggtta atattctgct caatggatgc ctgcaactcc ccgaaatatg
     4741 cccgggtcag tgacatcact tccttcctga ccttgttcat attgatcacg ctgcggctca
     4801 catccacact gtactctttc cagccccagt cactggtgtt tgcccatcga caaagcgtac
     4861 cccagacacc atcctgtcga cggcgacggg ttactgtctc cgttctttcc tccataagcg
     4921 cgctcagatt tgtttgtacc gcgagccggg tctgtaactg gctgactgcc ggaaaactga
     4981 tttttaccgt gaagccctca tcctccagtc gggcattgat gcgtccggcg atcttttctg
     5041 tggcatacag ggccgtacca cgaaaacctg tttcaatccc cctgacgatt ttttccagtt
     5101 cgggccgaaa ctgtgcctca gcctcacggt gcaggctggt cacggtcgat tcgatttgcg
     5161 tcatcagttc aagggctgcc ctgcgatcac tgaattttat ttcggggctg tccggatcaa
     5221 agtcccgcat cctgtcatgc tgatttccgg ttccgaaaat atcgtgaaag aaagcgaatg
     5281 cgtttctctc ccggggctgc gctgaatttt cttcttccag catttgctgt tctttacgtt
     5341 taccgcttct gaaatagtcg ttcagctcct cctccagtga ggcacagacc ttcgtcagta
     5401 attccccggt tttggtattg atgtcctcca tggccattct gacatcaccg gtcacctgat
     5461 tctgacattc ctcaatctcc tggatatccg ccagtaggct ggtaatatgc gcctgcagtg
     5521 actgaatgct ttgctgcagc ccctgatggc gtaatgacag atattcgctg acattttccg
     5581 cattctgcat cagttttgcg gcggcagaat caaccgccag tgccgccgct ctggaatggg
     5641 agctctgtat gacttccgtt atcagttgat cgataagtga gccttcccac aggtctgtcg
     5701 ccccttcagt tgccagttcg ctgtctttac agacgtaatc ttttttcatg cgaccgaagg
     5761 cttccctgac aaaatcatcg acccaggctt catcaacagg aagggttccg tttttccgta
     5821 actcatgaag cgcacggtta gccaggtacg cctgacgtga ggatccggga taaacgcggg
     5881 aggcgggcag cacatcgctg ttcagcattg ccggtacctt ctggcgtacg gcatctgctc
     5941 catcgccatt gcggtctttc tcatcaaatt tattgaccag cacaaacagg cggccggctg
     6001 atacgtcagc aatggcatta agctctttac ggacgtcttc atccgctttt gagttcatct
     6061 gggtgtaatc catcactgcc agcaccgcgg aagctttctg cagttgatcc cgcatcatca
     6121 cttccatctg tggctggccg gcttcattag ggccgggggt atccagcagt gtgagtgttc
     6181 cctggcaggc atccatcccc accagatggc tgaattccac gtcgatcacc ggcagtttct
     6241 gcacttctgc gtattcatca aaaggaaagt cactccccat tgccgcagca agacgaacca
     6301 gatcgtttaa cgatgccagt ccggtaaaga tttcctcctc cccgtggtat tcatttttga
     6361 gccagccatc atccgtcaga atatccagta gttcgcgggt atccccggtt tgctgcaggg
     6421 tctgtgcgac ctgctgtcct gccggggtgg cgagtttttc ctgcagtgtg attaataaat
     6481 tgcggacagg ctgagtatgt tccagatgga ggaccggctc agtttttcca ggaacgtgtc
     6541 ggatgagtgt cggaacagag gtcatggggc ggttacggtt gggcagaatt tcctgcccca
     6601 caatggcgtt gatggtggtt gatttacctg ctttcatcgt gccgacaaca gccagcacca
     6661 tctccctgcg ggcagttttg atttgttcgc cctccagctc ctcaatcctt ttcagtgctt
     6721 tctgtttatc aaaaagcagt ccgttttcgt tcttactgtc agataacaca tccggctcat
     6781 caaccatttg ccggagcaga ttgatgttca gttgcaaaag tcggtcggct tcatcacaaa
     6841 gcagggcgat gttcttttcg tgcattattt aaccttcctg agacgcattt tcatgacaac
     6901 cacggaggag gccatttatt acaaacgatc gtttaattct attaacttaa aaaacactac
     6961 gcaaggggac aacccgggta tggctgcgtt tgcatagtgt tttcatggag ttaaaaatct
     7021 gtaacaacag cctggtgcat caccaccagg ttcagaagaa aatccggttc cataccgcgc
     7081 gggcaacaga gaccacggtg tcacgaacag cgcgcagggc cgtacggaca acagaggcaa
     7141 cacagacgct ctccgctgtg tcaaatatcc ggtccaccgc accgataaac tgttcacggg
     7201 cctgagagcg gacagactcc gtgcgcagct cgtcctgcag tcgggtcatc aggggactgg
     7261 cggcatggtc gggaagcgct gtcatgagcg cactgaccag cgtatccggc tcccggccgg
     7321 tgcgggccga aacagccgga ataccgcctc cgttttttcg cgaatgttct gtgcctgtgc
     7381 gggagaaggc tgaatgccgg ccatatccca ttcatggcag ggttccgttt tgtcagcctg
     7441 cgtcaccaca aacagcacct gctgatgtcc ccggtgcagg atgtgtcgcc agaaatactc
     7501 atccacagac agggcccggt catcggcttt aatcagccac agcaccaggt ccagttcagg
     7561 cagaatgtca cggtacaggg cttcagactc tgcatccctg tcccggctct cgcccacccc
     7621 gggcaggtca gtgataacca tgctgtgacc gtgaccactc agacggaagc gccgtacttc
     7681 ccgggtgccg gcgtgaacat cactgaccgg ggtgaccacc ccctgaaaca gtgcattaca
     7741 gagtgaggat ttaccggccc cgcttttacc cataatgcca atcacgggtt cgtgactggt
     7801 gagtttgcgc agatgttcca ggatgtgacg ggaaagcgag taaggcaggg aggagagcgg
     7861 tttttcaatt gcctcaatgg catcagacgg attcatacat gtattcccgg tgaaaaaaaa
     7921 caaaaccccg cgcaccggaa aggtggcggg ggattcacgg agataatatc tgtctgaaat
     7981 tatttaggat gcaggtatat gcagttgatt tgtatctagt acagtactaa acctaatctg
     8041 gctgtccgct ctgtgccagg agcagacgtc taatatatct acttggttct taaattcagt
     8101 gcatcactgc aagcagctca acatcaataa attagggaat aactcacaac tttgactgtt
     8161 accacatggc atcatagtgt ttagagcatg cataagcacc aacgaggagt tttaacataa
     8221 tgggactgga tgatttcgga cttagtatct tagccggact tcttgcaaac agacttgatt
     8281 tctcaaaacc gaagggcacc tcagctcaaa tgaatgaagt tataccggat gtgattgaag
     8341 aaccagacaa attctcgcta agtgcaaatt tgccaaaaag attcaagaca ttcgacgtat
     8401 ggagtgattt ggacgaattg ctaaaggttg tgaaagagcc caaaatatct gttttgatag
     8461 aggagcaacc atcaacgtac tatcggctcc ctagcttggt tctggaatct caaatcacag
     8521 gggaatggta tgttttcccg cgaggccgca tgagttttga gggcaatgga ggtggcatac
     8581 agaacgcaga agtaatcttc aatcagttga aagaagaaaa tgttccggtg ggagtatggg
     8641 taatagatca agctcttctc gaccgcctcg ataacggaca agaatgttgg ccaaccatac
     8701 gattacaaat agtaccattc ttggccgcac catcgagcga atacccatgg ttcgaaatac
     8761 aacgaaacgt tgcaaaactc acagaattcc atttgactaa tgattaatag tgagccctaa
     8821 caggataatg gcacactgga tatgaccacc taagcagagg cagcacaggg gtaataaact
     8881 atgaacttct gcttttcgct cacagcggac cttcagcttc gttaacacgt ccgctccgtg
     8941 ccagtagcag actagtgatc gctaggcttg aattcattcg tattagcgcc aagtggataa
     9001 taaatggtga aatccattag tcattacttt atcataagct cgtt
//
LOCUS       DAZUDJ010000124         8997 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.126, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000124 DAZUDJ010000000
VERSION     DAZUDJ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8997
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.126"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(330..437)
                     /locus_tag="ACHY1N_004674"
     CDS             complement(330..437)
                     /locus_tag="ACHY1N_004674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HFS4046842.1"
                     /translation="MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK"
     gene            complement(813..920)
                     /locus_tag="ACHY1N_004675"
     CDS             complement(813..920)
                     /locus_tag="ACHY1N_004675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HFS4046843.1"
                     /translation="MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK"
     gene            1396..2667
                     /locus_tag="ACHY1N_004676"
     CDS             1396..2667
                     /locus_tag="ACHY1N_004676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transport family protein"
                     /protein_id="HFS4046844.1"
                     /translation="MQHNTLSKHNQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGL
                     KGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYF
                     LMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
                     KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQ
                     VLNPMNIAYRKREADKVLATRLALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAF
                     EQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRII
                     DTKKINSRMLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKV
                     AQLEKLRGFKAWLILLYGILLCLSPLLKLIE"
     gene            complement(2697..3701)
                     /gene="dppF"
                     /locus_tag="ACHY1N_004677"
     CDS             complement(2697..3701)
                     /gene="dppF"
                     /locus_tag="ACHY1N_004677"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding subunit
                     DppF"
                     /protein_id="HFS4046845.1"
                     /translation="MSTQEATSQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGISFN
                     LERGKTLAVVGESGCGKSTLGRLLTMIEMPTGGELYYQGQDLLKHDPQAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLTGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKDYGGQLVACFAVDQDENPQR
                     "
     gene            complement(3698..4681)
                     /gene="dppD"
                     /locus_tag="ACHY1N_004678"
     CDS             complement(3698..4681)
                     /gene="dppD"
                     /locus_tag="ACHY1N_004678"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HFS4046846.1"
                     /translation="MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGDAHAIFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPG
                     KYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLDDAGRPTL"
     gene            complement(4692..5594)
                     /gene="dppC"
                     /locus_tag="ACHY1N_004679"
     CDS             complement(4692..5594)
                     /gene="dppC"
                     /locus_tag="ACHY1N_004679"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HFS4046847.1"
                     /translation="MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLF
                     IAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSL
                     LVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            complement(5604..6623)
                     /gene="dppB"
                     /locus_tag="ACHY1N_004680"
     CDS             complement(5604..6623)
                     /gene="dppB"
                     /locus_tag="ACHY1N_004680"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HFS4046848.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLEL
                     GVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            complement(6774..8381)
                     /gene="dppA"
                     /locus_tag="ACHY1N_004681"
     CDS             complement(6774..8381)
                     /gene="dppA"
                     /locus_tag="ACHY1N_004681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter substrate-binding
                     protein DppA"
                     /protein_id="HFS4046849.1"
                     /translation="MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWH
                     DNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD
                     NTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY
                     QKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSA
                     KNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     AASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV
                     FEPVRKEVKGYVVDPLGKHHFENVSIE"
     gene            complement(8733..>8997)
                     /locus_tag="ACHY1N_004682"
     CDS             complement(8733..>8997)
                     /locus_tag="ACHY1N_004682"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046850.1"
                     /translation="GTALIVGCGATALFDLHTTHFPAKFAPHISLSINGFVTETIVFF
                     YICLNLFLRYLWLTLAFSAVRFSVHGINRSDIHLFLRFFSLNA"
BASE COUNT         2053 a         2460 c         2266 g         2218 t
ORIGIN      
        1 ttgttcaggt tcaagaatgg cccccgtgat gttgtcaggt gcatacctgc aacgtgcggg
       61 ggttttctct ctccagcaac caatgccacc agggataaag cccccgcaac attgcgcctc
      121 accggaaccc ttccggcttg ccgctgattc tacgactgtt tttctgttcc ggaatccgtc
      181 acgtcttcac tctgtgctgc gcattccgca gaatattatc cgcttgcaac cgttgcattt
      241 ttcttacgaa aaaggccgca gagtttcacc cctgcggcct gatccgggcg caaattgcca
      301 ttacggcagc ctgacgcccg catggcacgt tacttccgct tgttcagcca gttcacgatc
      361 atactggcaa gaataccagc aatgaccgga gccgctaaat catgccagaa ggccatgccc
      421 agttctgcga gcgtcatata gccgcctgta ttgtaatgac aacgtttcgc ggctattctt
      481 gtattgtttg gatgcaagaa tggcccccgt ggtgttgtca ggtgcatacc tgcaacgtgc
      541 gggggttttc tctctccagc aaccaatgcc accagggatt aagcccccgc aacattgcgc
      601 ctcaccggaa tccttccggc ttgacgctga ttctacgact gtttttctgt tccggaatcc
      661 gtctcatctt cactctgtgc tgcgcattcc gcagaatatt atccgcttgc aaccgttgca
      721 tttttcttac gaaaaaggcc gcagagtttc actcctgcgg cctggtccgg gcgcaaattg
      781 ccattacggc agcctgacgc ccacatgaca cgctacttcc gcttgttcag ccagttcacg
      841 atcatactgg caagaatgcc agcaatgacc ggagccgcta aatcatgcca gaaggccatg
      901 cccagctctg cgagcgtcat atagccgcct gtgttgtaat gacaacgttt cgcggctatt
      961 cttgagtggt ctaggttcaa gattagcccc cgttatgttg tcaggtacat acctgcaacg
     1021 tgcgggggtt ttctctctcc agcaaccaat gccaccaggg ataaagcccc cgcaacattg
     1081 cgcctcaccg gaaccctttc ggcttgccgc tgattttacg attgcttttt actgtcagca
     1141 cccggcaatc ttcctcattg cgcgatgcct tccagcttaa tttctttatt tgcaatagtt
     1201 gcagttcata tccgggctga ctccagactg gtagtgaaat gcgcaatttt gtagaattgc
     1261 gcctcctcgc gacctcccca gtgaatctgt tgcctcattt tttacatact gcgtattcga
     1321 cttctccacc tgttgcgcaa gagaaactgg gtttattcat ttttgcgagg ccgacttctt
     1381 tctggacagg actttatgca gcacaacaca ctatcgaaac acaatcagaa attgccgttt
     1441 acacgctacg acttcggctg ggttttatta tgcataggca tggcgattgg tgccggaacc
     1501 gtgctgatgc cagtacaaat tggcttgaag ggaatttggg tatttattac cgcagcgatc
     1561 attgcttatc ctgccacctg ggtagtgcag gacatttatt taaaaaccct ttctgaaagc
     1621 gattcctgta atgactacac cgatattatc agtcattacc tggggaagaa ctggggaatt
     1681 ttcctcgggg ttatctactt tttgatgatt atccacggga tttttatcta ctctctctcc
     1741 gtggttttcg acagcgcctc gtacctgaaa accttcggtt taaccgatgc cgatctttca
     1801 caatctctac tttataaagt cgctattttc gccgtactgg tggcgattgc gtctggtggt
     1861 gaacgattac tgtttaagat ttccgggcca atggtggtgg tcaaagtagg gattattgtc
     1921 gtgttcggtt ttgcgatgat cccgcactgg aatttcgcca atataaccgc cttcccgcaa
     1981 gcctccgtct ttttccgcga tgtcttgctt accattccat tttgcttctt ttctgcagta
     2041 tttattcagg tacttaaccc aatgaatatt gcctatcgta aacgggaagc ggataaagta
     2101 ctggcaaccc ggctcgcgct gcgtacccac cgaattagtt atatcacgct catcgcggtg
     2161 atcctgtttt ttgccttttc gtttaccttc tcaattagcc acgaagaagc cgtttctgcc
     2221 tttgaacaaa atatctcggc actggcgctg gccgcgcagg tgatccctgg acatatcatt
     2281 catatcacct ctacggtgct gaatatcttt gccgtactga ccgcattctt tggcatttat
     2341 ctcggtttcc acgaggctat taaaggcatt attctcaatc tgttaagccg aattattgat
     2401 accaagaaaa ttaactcacg catgctgact ctggcgatct gcgcttttat cgtcattaca
     2461 ttgacgattt gggtttcgtt tcgtgtatcg gtgctggtgt tctttcagtt gggaagcccg
     2521 ttatatggca ttgtgtcgtg cctcattccg tttttcctga tctataaagt cgcacaactg
     2581 gaaaaacttc gcggatttaa agcctggcta attctgcttt acggcatttt gctatgcttg
     2641 tcgccactgt tgaagctgat tgagtaaacc ggagcgcatg gccccggttt tgtgagttaa
     2701 cgctgcggat tttcatcctg atcaacagca aaacaagcta ccagttgacc gccgtagtct
     2761 tttagctgcg gctgcaactg ggtgcagggg ccgaagcgcc gacgacagcg ggcgttgaag
     2821 gcgcaacccg gcggtggatt cagcgggctt ggcagttcac cggtgagttt gatgcgttcg
     2881 cggcgatcgt ccgggttcag gcgcggcgtc gcggagagta gcgcctgagt gtacggatgg
     2941 cgcgggttat tgaagatttg gtctttcgtt cccttctcca cgcagcggcc caggtacatc
     3001 accatcactt catcggcaat gtgctccacc accgacaggt cgtgggagat aaagacataa
     3061 gaaagcccca gttcctgctg taaatccatc atcagattca gcacttgcgc acgcactgag
     3121 acgtccagcg cagaaaccgg ctcatcggca atcaccacat ccgggtcgag catcagacca
     3181 cgggcaatag cgatacgctg acgttgtccg ccggagaaca tatgcggata gcggtcatag
     3241 tgctcggttt tcaggccgac tttcgccatc atcgacaggg ctttttcccg acgctgttct
     3301 ttgcttaagc tggtgttaat aagcagcggc tcttcgagaa tttgcccaac ttttttacgc
     3361 ggattcagcg aaccgtaagg gttctggaag acgatctgga ttttctgccg acgcagcttc
     3421 tgcgcctgcg gatcgtgctt aagcagatcc tgcccctggt aatacagctc gccaccggtg
     3481 ggcatttcaa tcatcgtcag caaccgaccg agggtcgatt taccgcagcc agattcgccc
     3541 actactgcca gcgttttgcc acgttcaagg ttaaacgaaa tgccatccag cgctttaacc
     3601 agacgttccg gcgcgaacat gcctttcttc accggataat gttttttcag gtcgatagcc
     3661 tgcaacagcg gttgttgcga ggtggcctct tgcgtactca tagtgtcggc ctcccggcat
     3721 catcaagtgg gtaatggcat ttggactgac gcccatcagc gagcatattc agcgccggtt
     3781 cttcagcgcg acatctgtca gtggcatagg ggcagcgcgg gttaagcagg cagccgttcg
     3841 ggcggtcgta cttaccggga acgacacctg gcaacgacgc cagacgttct ttgtcctgag
     3901 caaattctgg cagcgcacgc agcaatgcct gagtatacgg gtgacgcggc gcatggaaga
     3961 tggcgtgcgc atcaccggtt tccaccacct ggcctgcata catcacgatg attttatgtg
     4021 ccgcttccgc caccagcgcc aggtcatggg taattaacac cagcgccatg ttctctttct
     4081 gctgtagctc cagcagtagt tcgatgattt gcgcctgaat ggtcacgtcc agcgcggtgg
     4141 tcggttcatc ggcaatcagc agttttggcc gacaggcaat cgccatggcg atcatcacgc
     4201 gctggctcat gccgccggaa agctgatgcg ggtaaacatc cagacgcgat gccggatcgg
     4261 gaataccgac ctgattcagc aggtcaatcg ctcgctgacg gcgggtactt ttgttgccgc
     4321 cctgatgcac cttaatcgct tccataatct ggaaacccac ggtgtagcac gggttaaggc
     4381 tggtcatcgg gtcctggaag atcatcgcca cttcggcacc caccaggttg cggcgctctt
     4441 tttctgagat acgctgcaaa tcctggccgt taaactccag tttttctgcc attacgcggc
     4501 ccggataatc aatcagcccc ataatcgcca gtgaactgac cgacttaccg gagccggact
     4561 cacccacaat cccgaccact tcgccctgtt ttacgctgta gctgatgcgg tctacggcgc
     4621 ggaacggcgc gctttcgtcg ccgaaatgca ccgataattt atctacattt aataacgcca
     4681 tctcgaacct cttactgctt cagtttggga tcgagcgcgt cacgcagacc gtcacccatc
     4741 aggttaaatg ccagcaccgt cagcaggatc gccagacccg ggaaggtcac gacccaccag
     4801 gcgctttgcg cgaactgcaa cacgtcggag agcatggtgc cccactcagg cgttggcggc
     4861 tgtgccccca tgccgaggaa accaagagca gccatatcga gaatggcgtt agagaaaccg
     4921 agcgacgcct gaacaatcag cggcgcaagg cagttcggga agatgttaat aaacatctga
     4981 cgcatcgccc cggcacccgc cacgcgagac gcggtgacgt aatcgcggtt aacttccacc
     5041 agcacggcgg cgcgggttaa gcgcacatag tgcggcaagg caacgaaggt cagtgccagc
     5101 gcggcgttac caatcgacgg gccgaaaatt gccaccagca ccagcgccag cagcagactt
     5161 ggcagcgcca gcatgatatc gaccacgcgc ataatgatgt tatcgaccag gccgccaaag
     5221 taaccggcga tcaggccgag aataacgccc ataatcagcg ataacacaac taccagacag
     5281 ccaaccagca gcgacaggcg cgcaccgtac atcaggcgcg acagcacatc acggcctacg
     5341 tcatcggtgc ccagcaagtg cgccatgctg ccgccttcct gccaggctgg cggggcgagc
     5401 agtgcatcgc ggaactgttc cgccgggtta tagggtgcaa tccagttggc aaagatcgcg
     5461 atgaacagca cgatgacgac gtaaaccagc ccgacgaccg cgcctttgtt gcgtttaaaa
     5521 tagtgccaga actcctgtaa cggggtcatc ggcaccggtg cgctaatcac tttattttca
     5581 gtaacctgtg acatgatgtc cccttacttc ttatgacgaa tacgcgggtt caccacgccg
     5641 tacagcagat cgaccagcaa gttgacgagg ataatcatcg tcgccaccag caatacgccg
     5701 ccctgcacta ccggatagtc gcggcgttgc agtgcgtcaa tcaaccagcg tcccagaccg
     5761 ggccacgaga agatggtttc ggtcagaatc gcccccgcca gcaatgttcc cacctgcagg
     5821 ccgataacgg tcaccaccgg cagcatcgcg ttacgcagcg catggacgat aatcacccgc
     5881 atgcgggtta gccctttggc gcgcgcggtg cggatgtaat cctcgcccag cacttccagc
     5941 atcgaggagc gtgtcatacg cacaatgacc gccagcggaa tagtacccag cacaatggca
     6001 ggcaagatca tatgggcgac ggcatcgata aagttgccgt cttcacccca gatggcggtg
     6061 tcgattagca taaaaccggt taacggattg gagtcatcga ggaacaccat atcgctcacg
     6121 cgaccggaga cgggcgtcag gttccagtgc accgaaacca gcatgatcag catcatgccc
     6181 caccagaaga tcggcatcga gtagccggtc agcgccaggc caaccgctgt gtgatcgaaa
     6241 atggaaccgc gtttaaccgc agccagcaca ccaaccggaa taccgactgc cgtagcaaaa
     6301 atcatcgcgc agacgccaag ttccagcgtg gcctgaaagc gcggcacgaa ctcttcccat
     6361 actggaattc ggcttttcat tgaaatgcct agatcgccgt gcattacgcc ccaaatgtaa
     6421 tggagatact gctgccacat cggtttatct aagccgagtt cagccagcag ctgcgcgtga
     6481 cgctcagggg agatcccacg ttcgcctgcc atgatcatca ccggatcgcc cgggatcatg
     6541 tggacaaagg caaatgtgag aagggtaata ccgataaacg tggggatgac gagtcccaaa
     6601 cgtcggagaa taaactgcaa cataacccgg attctctata gtgacccgca gcctggaact
     6661 gcgtgtctgt attgctcaca aatcaattcc cgcccttgtc ggacagagaa tgaagtattg
     6721 ctgccggatg gcgctgcacg cagaggcaca gcgccaccgg gtatggcttt taattattcg
     6781 atagagacgt tttcgaagtg atgtttgcct aatggatcaa ccacatagcc tttaacttct
     6841 ttgcgtaccg gttcaaacac ggtggagtga gcgatgatca gtgccggagc ctgatcgtgc
     6901 atcaccacct gcgcttgctt gtacagttca acgcgtttgt tatggtcgtc ggtagcacgc
     6961 gccggttgaa tcagatcttc aaacggtttg tagcaccatt ttgagtagtt agaaccttgt
     7021 tcagaggcgg cgcagctgaa cagggtggcg aagaagttat ccgggtcccc gttatcgcca
     7081 gtccagccca tcattaccgt ctgatgttcg ccatctttcg cacgcttgag gtactcaccc
     7141 cattcgtagg tgacgatttt ggcctgcacg cccactttcg cccagtctgc ctgaatcatc
     7201 tccgccatgc ggcgagcgtt cgggttatac ggacgttgta ccggcatcgc ccacaggtcg
     7261 atggagaaac ctttttccag acccgcttct ttcagcaagg ctttcgcttt ttcaggatcg
     7321 taggtgtaat cctgaacgtc gtcgttatag ccccacatgg ttggcgggat caggtttttc
     7381 gctgatacac ccgcgccctg ataaaccgct ttgatgatcg cgtctttgtt caccgcgtag
     7441 gtcagtgcct ggcgaacttt cacgtcatcc agcggttttt tctgcacgtt atacgagagg
     7501 tagccgacgt tcagccccgg catttccatc aggttgatgg atttatcctg cttcatgcga
     7561 gcgatatctg ccgggttcgg gtacggcatc acctggcatt cattcttctg caatttcgcg
     7621 taacgcacgg aagcatcagg ggtaatagag aagaccagcg tatcgatctg cggtttggtg
     7681 ccccagtagc catcaaacgc tttgtagcgg atacgggaat ctttttggta ctgctgtaac
     7741 tggaatggac cggttccgat tgggttgagg tccagttttt ccggtgtacc ggctttcatc
     7801 atcgcatcag catattcttt tgacagaata gaggcgaagt ccattgccag atcagcgagg
     7861 aacggcgctt ccgggcgagt cagcacgaac tgaactgtgt tgtcgtccac ctttttcact
     7921 tcgctgatca gctccggcaa gcccatgcct tcgaagtatt cgtagctacc gccagaaact
     7981 ttatggtacg ggttttgcgc gtttttctga cgatcgaacg agaacaccac gtcatcggcg
     8041 ttcagttcgc gcgtcggttt gaattcttta ttgtcatgcc acttcacacc tttacgcaga
     8101 tggaaggtat aggttttacc gtcttcgctg acttcccact tttcagcgag gcccgggatc
     8161 acttcagtgg tgccgatttt aaattcaacc aggcggttat aaagcggtac ggaagaggcg
     8221 tcataggtgg tgccggaggt aaacagctgc gggttaaacc cttccggaga tccttctgag
     8281 caataaacca gagttttagc ctgaacactt gctgcgacgg tcatagccac caggctgaga
     8341 ccaagcttca gcatccctga ctttttcaag gaaatacgca ttattctgct ccaattgtga
     8401 tgtttgttgt tttaaccctt tgcagtgggt tgtcgctgcc tgaccttttt tgttttttgc
     8461 ccggtcgggt caacgttatg aggtggggat gccgtactaa ttaacatcag tgtaacagtg
     8521 cggatcctcc ataaaatgcc cctcgtgacc tacaatctgt caacagaatg tgaaaacgtc
     8581 aatacagcca accgggattt acaccaacgg tgagaatcca caaacaaaga ttaaaaaaac
     8641 ttcaaacagc tatttgcagc agagaaattt gtgctactcc aacatgacca gaacaatcag
     8701 cttaatattt agcaacattt ggtgattaag ttttatgcat ttaatgaaaa aaatctgagg
     8761 aaaaggtgga tatctgagcg attaatacca tgaacgctaa aacgcacagc ggaaaatgcc
     8821 agggtcagcc ataagtaacg caaaaaaaga tttaagcaaa tataaaaaaa gacaatggtt
     8881 tctgtcacaa atccgttaat ggatagtgag atatggggcg caaatttggc agggaaatgt
     8941 gtggtgtgta ggtcgaataa ggcggtcgcg ccgcatccga caataagtgc ggtgccg
//
LOCUS       DAZUDJ010000125         8629 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.127, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000125 DAZUDJ010000000
VERSION     DAZUDJ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8629
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.127"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(211..804)
                     /locus_tag="ACHY1N_004683"
     CDS             complement(211..804)
                     /locus_tag="ACHY1N_004683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014226759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046851.1"
                     /translation="MKDYKPRYEELYRYYQVWLTDFTKLTVRSGMCHQNIYHHHTLTV
                     GSLKFPGEEEVIAIVPQCLHRIIYGRAAAPLTVNEDLSVSLFTQEHLLTHHPMLEGIL
                     LSECVRLKQRPLANKLISLFRQFSGSELRLKLVWLCWYDLMLGNCLDDWTDNLRFKKD
                     KEMDIWINNRQAENPALTIMMDEYVCFAWRTTAEPLS"
     gene            complement(901..1107)
                     /locus_tag="ACHY1N_004684"
     CDS             complement(901..1107)
                     /locus_tag="ACHY1N_004684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014226758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4046852.1"
                     /translation="MTTRPSLTEDQFVDMAFITSLLQMTDKWIYKLIKDGVFPKPIKL
                     GRSSRWLKSEVENWLQERIDQSRK"
     gene            1591..2475
                     /locus_tag="ACHY1N_004685"
     CDS             1591..2475
                     /locus_tag="ACHY1N_004685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046853.1"
                     /translation="MVKLVGNDSSKIKYLENKLIENGYHFYSGGVDKDYREYQLRVFN
                     YLVSQNVSEQNINSFFAEVDNSYTRGFPSESELDWYRNDPRASLWLSCELYEKLKEET
                     PKYNIDFLSPEALQPDHNVRIEAIRHCMDEWPMYFTTPAEFIKDKSIEWAELLDQHDL
                     FRSVRSSKVDVCSWLRDYLRGNTSIGLKRICGNSSEEIMSWCYASYFIWRKNNLHSPD
                     SVELFIRKFKSAWSTQKNRNKNKEEKKLVTMSVNISQQAHDMLRDMSMKDSMSNNAII
                     ESAILRLYNIKNSKVRSK"
     gene            2560..3435
                     /locus_tag="ACHY1N_004686"
     CDS             2560..3435
                     /locus_tag="ACHY1N_004686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HFS4046854.1"
                     /translation="MNKPDGLQAFEQPLASLPCTLRQLILERIQNLTHYEPVIGIMGK
                     SGTGKSSLCNELFQGEVSPVSDVNACTRDVLRFRLRSGRHSLVIVDLPGVGENGRRDH
                     EYRALYRRMLPELDLVLWVIKADDRALTLDEQFWLGVMQPYRQKVLFVINQADKIEPC
                     YEWDTLTSKPSTHQQGNLKAKQAAIMAMFKPHHPVCAVSASTGWGIEDMVAAMMRCLP
                     DRATSPVVTQLHGRLCTEPVKSQARDSFGDAVGRVFDTAESSSLLPAPLKKVIRTVRD
                     AVVSVARAVWDWIFF"
     gene            3679..4395
                     /locus_tag="ACHY1N_004687"
     CDS             3679..4395
                     /locus_tag="ACHY1N_004687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012543038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4046855.1"
                     /translation="MTLQERRHDRLAVRLSLIISRLVSGETLFIRKLATEFGVSERTL
                     RRDFRERLMYLDLDYYQGQCSLRTDIHSTRQEIDILTFAHRTGLAGVFPGFDRRLVSS
                     LLDCDDRPCLVWHQDRPHPPAGKLSFYRLVRAISGCQRITILTEGERHEAVAPYRLIA
                     LDGYWYLVAEHNRQLRVFRLGEIHLVRPSRETFIRSELLYQLSEDKHFISALPHFRFI
                     QQSLNSFSPSESRGQSGQTD"
     gene            4431..4883
                     /locus_tag="ACHY1N_004688"
     CDS             4431..4883
                     /locus_tag="ACHY1N_004688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046856.1"
                     /translation="MKKLKLLSLLPVMFFPLLIAGNAHAARPYSGFLPAAVNNKSGNI
                     FWCDAHRQVRKLCTATEVDSMGWFIVVRSKPSRDCPGGIWGWITPSKDDVATGYTITP
                     GKEFNLTMKDMCSPDMKVTFRPNKKDPRYDDLVGIYAGKEAFRYKQIK"
     gene            4955..5401
                     /locus_tag="ACHY1N_004689"
     CDS             4955..5401
                     /locus_tag="ACHY1N_004689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012543036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046857.1"
                     /translation="MRLPYVIVTLAMLASVSTAQAIPNMWTSGFGMGVTEYIITSPDK
                     VVFNLNCTGNPDAQNILQHGVDLTLPDGISVSSHDDGTEITVVMDNSQYPLPSFLGWR
                     NGDNAWVSFIDALSQAANFDVYVNDKKVGTFSPGLKNTQKELSDLS"
     gene            5548..6369
                     /locus_tag="ACHY1N_004690"
     CDS             5548..6369
                     /locus_tag="ACHY1N_004690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF932 domain-containing protein"
                     /protein_id="HFS4046858.1"
                     /translation="MRLASRFGRINQIRRDRPLTHEELMSHVPSVFGSDKHESRSDRY
                     TYIPTITILESLQREGFEPFFACQTKVRDQSKREHTKHMLRLHRAGQLTGHQVPEIIL
                     LNSHDGSSSYQMLPGLFRGVCTNGLVCGQSFGEVRVPHKGNVVEKVIEGAYEVLGVFD
                     RVEEKRDAMQSLALPAPARHALANAALEYRFGEDHQPVTVSQLLTPRRREDYSDDLWT
                     VYQRVQENLMKGGLSGRTAQGKSSRTRAVTGIDGDVKLNRALWVMAENMLEFFGR"
     gene            6400..6843
                     /locus_tag="ACHY1N_004691"
     CDS             6400..6843
                     /locus_tag="ACHY1N_004691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004128347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HFS4046859.1"
                     /translation="MNTQNLEFAEQAAITASAVPDELRIGFWPQHFGSVPQWITLESC
                     IFDWMDRLCTDYHGGIWSFLTLSNGGAFMAPESEHDEKWALFNSMNGNGAELTGEAAG
                     IVACLMTYSHHACRTECDAMTEHYYRLRDFALNHPECSAIMHLID"
     gene            6856..7398
                     /gene="radC"
                     /locus_tag="ACHY1N_004692"
     CDS             6856..7398
                     /gene="radC"
                     /locus_tag="ACHY1N_004692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017694582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFS4046860.1"
                     /translation="MNTTISPLLSQPELFPVSVMAQHGCLLPTTSGLTPYAQRTIRRA
                     MNLLDKYLRQPGIAFTSSTAARDWLRLHLARQEREVFMVLYLDNQHRLLESETLFAGS
                     VNHVQVHSREVVKSALRFNAAAVVLAHNHPSGDPEPSQCDRNITGRLKEALELVDVKT
                     LDHLVVGRDGIVSFAERGWL"
     gene            7395..7616
                     /locus_tag="ACHY1N_004693"
     CDS             7395..7616
                     /locus_tag="ACHY1N_004693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HFS4046861.1"
                     /translation="MKIISKRQAMALYRQHPGSRLFRFCTGKYKWSGSICHYAGREVQ
                     DIRGVLAVFAERRQDRNGPYVILRSITLN"
     gene            7642..8007
                     /locus_tag="ACHY1N_004694"
     CDS             7642..8007
                     /locus_tag="ACHY1N_004694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HFS4046862.1"
                     /translation="MNNHSESGTKPENPACQQWGLKCAITPCFGARLVQEGNRLHFLS
                     DRAGFSGAFAVDVAMRLDQAFPLMMKQLELMLTSGELNPRHPHCVTLYHNGLTCEADT
                     LGSCGYVYIAIYPEQTEPQ"
     gene            8046..8417
                     /locus_tag="ACHY1N_004695"
     CDS             8046..8417
                     /locus_tag="ACHY1N_004695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TA system toxin CbtA family protein"
                     /protein_id="HFS4046863.1"
                     /translation="MQTISSHPTRATQPCLSPVEIWQRLLTCLLSQHYGLTLNDTPFS
                     NETTILEHIDAGVSLCDAVNFLVEKYELVRIDCNDCSVMEKSPFITSIDILRARKASG
                     LMKRNSHKTVTRVTAGRLQEL"
BASE COUNT         2220 a         1974 c         2141 g         2294 t
ORIGIN      
        1 attgttttgc ataggatgag tttctttagt gctggcaagg gccagccagt ggaatgaacc
       61 aggccttaag gaaggaccat ggcagaggga gttgtatgga ttagggggga tagaagtaaa
      121 aagggagtgc ctattaatta tattaattaa cctaaattaa ttttcactcc ccaataaccc
      181 tcaaatccct tgcaggacta tggatgaagc ctaactcagt ggttcagctg tcgtccgcca
      241 tgcaaagcag acatactcgt ccatcataat ggtcagcgca gggttttcag cctgccggtt
      301 attgatccag atatccatct ctttgtcttt tttgaacctg aggttgtcgg tccagtcatc
      361 aaggcaattc cccagcatca aatcgtacca gcacagccag accagcttca gacgcagctc
      421 actaccgctg aactggcgga acaaactgat gagcttattt gccagagggc gttgttttaa
      481 acgcacgcac tcagacagca aaatcccctc cagcatggga tggtgagtca gcagatgctc
      541 ctgggtaaat aaactgacgc tcaggtcttc attaacagtc agtggggctg ctgctctacc
      601 ataaataatc cggtgcaggc actgggggac aatagcaata acctcttcct ctcccggaaa
      661 cttaaggctg ccaaccgtca gggtatgatg gtggtagata ttctggtgac acatccccga
      721 tctgaccgtc agcttcgtaa aatcagtcaa ccagacctga taatatctat aaagttcttc
      781 gtaacgaggc ttgtaatctt tcatagttca tattccttaa ggcttaaatg acagacagca
      841 gaaaacctcc ggagtaaccg gatagttatt attctgctga gggtttagtc tggtgggagg
      901 ttatttacga gactggtcga ttctttcctg tagccagttt tcgacttcgc tttttaacca
      961 tcgggagctt cggcccagct tgatgggttt gggaaagact ccatccttaa tgagcttata
     1021 aatccactta tctgtcattt gcagcagact ggtgataaat gccatgtcaa cgaactggtc
     1081 ttcggtcagt gaggggcggg tagtcatgat ttgtatctcc ggttaagaaa ggtaagccgg
     1141 attagtgaag tttgataacg acgactgctc cgggacatat ccaggtggag atacgtaaaa
     1201 aaagagagtt atgattacct ctgttcctac tttgatatcc gtgcaggtct ttttcaaata
     1261 aagaagataa tgaagtgtga tttctggtag ggccattttt tagatgggaa attgtatggc
     1321 aactagttgc tgtctatatt ggaagcggtt gccactatta atcaaaaaat gtaagaagag
     1381 tgtgtattaa ctagaatggt aataatttct atatagcgct gaagagagaa aagtgatcat
     1441 cattctcatt tacctatgta aactacatca cataattgtc atttttccct tggttcttat
     1501 acatgaatgt tattgatata cagtatggag ttatgctaaa agtcattaat tcactgtaaa
     1561 tcacttagtg atatcaagga aggtgccggt atggttaagc tagtggggaa tgacagtagt
     1621 aagattaaat atcttgaaaa taaattaatt gagaatggtt atcacttcta ttctggtggg
     1681 gttgataaag attaccggga atatcagtta agggttttca attaccttgt ttcacagaat
     1741 gtttctgagc agaacattaa ttctttcttt gctgaggtgg ataatagcta tacaagaggt
     1801 tttccatccg agagtgaact tgattggtat cgtaatgatc caagagcaag cttatggttg
     1861 tcttgtgagt tatatgagaa attaaaggaa gaaactccta agtacaatat tgattttcta
     1921 tctccagaag cattgcaacc tgatcataat gtgagaattg aagcgatacg tcattgtatg
     1981 gatgaatggc ctatgtattt tacaacaccg gctgaattca ttaaggataa aagtattgag
     2041 tgggctgagt tacttgatca acatgattta ttcagaagtg ttagatccag taaggtcgat
     2101 gtctgttctt ggctaagaga ttacttaagg gggaatacat caataggtct gaaacgtatt
     2161 tgtggtaatt cttccgagga aataatgtcg tggtgctatg caagttactt tatttggaga
     2221 aaaaacaacc tgcattctcc agattctgtc gagttgttca ttagaaagtt taagagcgcc
     2281 tggtctactc aaaaaaatag gaataaaaat aaagaagaga aaaaacttgt gacaatgagt
     2341 gtaaatatct ctcagcaagc tcatgatatg ctgagagata tgtctatgaa agactcgatg
     2401 tcaaataacg caattataga gagtgctatc cttaggttat ataatattaa gaatagtaaa
     2461 gtacgttcca aataatttca gacagatatt atctacgtga acccccgctt tcctgactgg
     2521 atcgcggggt tttttaattt ttcacgctga gactactgta tgaataaacc tgacggcctt
     2581 caggcctttg aacaaccgct tgcgtcgctt ccgtgcacac ttcgccagct tattcttgaa
     2641 cgtatccaga acctgaccca ttacgagccg gtgattggaa tcatgggcaa aagtggtaca
     2701 ggtaaatcct ctctctgcaa cgaacttttc cagggcgagg tgtccccagt gagtgacgtg
     2761 aacgcctgta ctcgcgacgt actgcgcttc cggttgcgca gcggtcgtca cagtctggtg
     2821 attgtcgatt taccgggtgt aggtgaaaac gggcgacggg atcatgagta ccgggccctg
     2881 taccgtcgaa tgctgccgga gctggacctg gtgctgtggg tcattaaggc cgatgatcgg
     2941 gcactgacct tggacgagca gttctggctc ggtgtgatgc aaccttacag gcaaaaggta
     3001 ctgtttgtga ttaaccaggc cgacaaaatc gaaccctgct atgaatggga taccctcacc
     3061 agcaaacctt caacacacca acagggaaat cttaaagcga agcaggctgc gattatggcg
     3121 atgtttaaac cacatcatcc ggtctgtgcg gtgtccgcca gcactggatg gggcattgag
     3181 gatatggtgg cagccatgat gcgctgtctg cctgaccgcg ccaccagccc ggtggtgaca
     3241 caactgcacg ggagactctg cacagagccg gtaaagtcgc aggcccgtga cagtttcggt
     3301 gacgctgtgg gccgtgtttt cgatacggca gagtcatcgt cattactgcc tgcgccactg
     3361 aaaaaggtga ttcgtaccgt gcgtgatgcg gtggtgtcgg tcgcacgagc cgtctgggac
     3421 tggatattct tctgatatcg caattttctc tgcgaatgat gaactggttg ttaatgatgt
     3481 gttgattgtg gacacgtctt ttccactgcg ttttatcatc aattaaatca ggcgaagcat
     3541 cattatctgt cagacgagcg cccacaaggc tggactgctc ataaaaaata gttccgatgt
     3601 tgtccatacc ctgtccactc cttcctttaa agtaatcatt attaattcat agagttaact
     3661 tctcaggaga aatctttcat gacgcttcag gagcggcgac atgaccggct tgccgtcagg
     3721 ttgtcgttga ttatcagccg cctggtgtcc ggtgaaactc tgtttattcg caaactggca
     3781 actgaattcg gggtgtcaga gcgcacgctg cgtcgtgact ttcgggaacg tctgatgtat
     3841 ctcgacctgg attactacca ggggcagtgc agtctgcgca cggatattca cagtacgcgg
     3901 caggaaatag atattctgac ctttgctcac cgcacggggc tggccggggt tttcccgggc
     3961 tttgaccggc gactggtcag cagcctgctg gactgtgatg atcgaccctg tctggtatgg
     4021 catcaggaca gacctcatcc cccggcagga aagctctcct tctacaggct ggtcagagct
     4081 atttcgggat gtcagcgcat caccattctg actgaagggg agcgtcatga ggccgttgca
     4141 ccttaccggc taatcgctct ggacggttac tggtatcttg tcgctgaaca taacaggcaa
     4201 ttacgtgtct tccggctggg tgagattcat ctggtaaggc catcgcggga aacatttatt
     4261 cgcagtgagc ttctctatca gctgtcggag gacaaacatt ttatctctgc cttacctcat
     4321 ttccgtttta ttcagcagtc gctgaattca ttttctccat cagaaagtcg ggggcaatcc
     4381 ggacaaactg attagagatg gtctccacaa ttgaatgtaa ggttaatcta atgaaaaaat
     4441 tgaaattatt gtctttactg ccagtcatgt tttttccctt acttatcgca ggtaatgctc
     4501 acgcagcacg tccttatagc gggttcctgc ctgcggcagt gaataataaa agtgggaata
     4561 tattctggtg tgatgcccac cgacaggtca gaaaactgtg tacagcgacg gaagtggatt
     4621 caatgggatg gtttattgtt gttcgctcga aaccttccag agattgtccg ggtggaatat
     4681 gggggtggat cactcccagt aaagacgatg tggcaacagg ttataccatt acgccaggta
     4741 aagaattcaa cctcaccatg aaggatatgt gcagtcccga tatgaaagta acgttccgcc
     4801 cgaataaaaa ggaccctcgt tatgacgatc tcgtcgggat ttatgcaggg aaagaagcgt
     4861 ttcgctacaa acaaataaaa taatccaact gttttttcgt tactttattg ttttaaacaa
     4921 caaaagcttt attacatgat ttgaggacaa cattatgcga ctgccttatg taatagttac
     4981 attagctatg ctggcttctg tatcaacagc acaggctatt cccaatatgt ggacgagtgg
     5041 ttttgggatg ggtgtgaccg aatatatcat taccagcccg gataaggtgg tgtttaatct
     5101 gaactgtact ggcaatccgg atgcgcagaa tattctgcaa cacggtgttg atctcaccct
     5161 gcctgatgga atatcagtaa gctctcatga cgacgggacg gaaataacgg tcgtcatgga
     5221 taacagtcag tatccgttac cgtcattcct cggctggcga aacggtgaca atgcctgggt
     5281 gtcatttatt gacgccctga gccaggctgc gaattttgat gtttacgtca acgataaaaa
     5341 agtcggcacc ttcagtccgg ggctgaagaa tacgcaaaaa gagctgtctg acctcagtta
     5401 gtgccggacc acacactaca gcgattagtt acttacattt cagacctctc caccccacaa
     5461 cataccaaca ccagatagca acaggccatg ctccttcggg aacatggcct ttttgttttt
     5521 atttcattat cagataagga gttagctatg cgattagcca gccgctttgg tcgtataaac
     5581 cagatacgcc gtgaccggcc tctgacccat gaagagctga tgagtcatgt acccagcgtg
     5641 ttcgggagtg acaagcatga atctcgttca gaccgttata cctacatccc gaccatcacc
     5701 atcctcgaaa gcctgcagcg tgaaggcttt gagccgttct ttgcctgcca gacaaaggtc
     5761 cgtgaccaga gcaagcggga acacaccaaa cacatgcttc gcctgcatcg tgccggtcaa
     5821 cttaccgggc atcaggtacc ggaaatcatt ctgcttaaca gccacgacgg ctcatcaagc
     5881 taccagatgc tgccggggct gtttcgtggc gtttgtacca acggcctggt ctgcggtcag
     5941 tcgttcggag aggtacgggt gccacataaa ggcaatgtcg ttgagaaggt gattgaaggg
     6001 gcttacgaag tgctcggggt gtttgaccgg gtggaggaga agcgcgatgc aatgcagtca
     6061 ctggcgctgc cagccccggc ccgtcacgcg ctggcaaatg ctgcgttgga atatcgcttc
     6121 ggtgaggacc accagccggt cacggtatcg cagttgctga ccccacgtcg ccgggaggac
     6181 tacagcgatg acctgtggac cgtctaccag cgcgtgcagg agaacctgat gaaaggtggt
     6241 ctgtcagggc gaaccgctca ggggaaaagc agccgcaccc gtgctgttac cggtattgat
     6301 ggcgatgtga agctcaatcg cgccctgtgg gtgatggcag aaaacatgct cgagtttttc
     6361 gggcgttaaa caacagttcc tgcataagga gatagtttaa tgaatacaca aaatcttgag
     6421 ttcgctgagc aggcagcaat aactgcctca gcggtccctg acgagttacg catcggcttc
     6481 tggccgcagc actttggctc cgttccgcaa tggataaccc tggagtcctg tatctttgac
     6541 tggatggacc gcctgtgtac cgattatcac ggcggtatct ggagcttttt gacgctcagc
     6601 aatggcggcg cttttatggc tcctgagtca gagcacgatg agaagtgggc attgttcaac
     6661 agtatgaacg gcaacggcgc ggaacttact ggcgaagccg cagggatagt cgcctgtctg
     6721 atgacataca gccaccacgc ttgtcgcacc gagtgtgacg cgatgactga gcactattat
     6781 cgcttacgag acttcgcgtt gaaccatcca gagtgcagcg caattatgca tctcatcgac
     6841 tgagtcatac cgaatatgaa taccacaata tccccactgt tatcgcagcc tgagcttttt
     6901 ccggtgtcgg tcatggctca gcatggctgt ttactcccta cgacttccgg actgacaccc
     6961 tacgcccaac ggaccattcg ccgcgctatg aacctgctgg ataaatatct gcgtcagccc
     7021 ggtatagcct ttacctcaag cactgcagcc cgtgactggc tccggttaca cctggccaga
     7081 caggagcggg aggtgtttat ggtgctctac ctcgataatc agcatcgttt actggagagt
     7141 gaaacgctgt tcgccggttc ggtaaaccat gtgcaggttc attcccgtga ggtagtgaag
     7201 tcggcgcttc gtttcaatgc cgcagctgtc gtgctggcgc ataaccatcc ctccggtgat
     7261 ccggagccca gccaatgcga tcgcaacatt acgggcaggc ttaaagaagc gttagaactg
     7321 gttgatgtga aaacgctcga tcatcttgtt gtcggtcggg atggcattgt gtcgttcgct
     7381 gagcgaggtt ggttatgaaa atcatcagta aacgtcaggc aatggctttg taccgacagc
     7441 atccaggctc tcggctgttt cgcttctgta ccggcaaata taaatggtcc ggcagtatct
     7501 gccattatgc tggccgggaa gttcaggaca tacgcggcgt tctggctgta tttgctgaac
     7561 gtcgtcaaga ccgcaatggt ccctatgtca ttcttcgaag cattactctt aattaatcct
     7621 tccctttaat caggaacaat aatgaacaat cactcagaat ccggtacaaa gccggagaat
     7681 cccgcctgcc agcagtgggg gcttaaatgt gctattaccc cctgttttgg tgcccgcctg
     7741 gtacaggagg gcaaccgatt gcattttctc tctgaccgcg caggatttag cggggcattt
     7801 gccgtcgatg ttgcaatgcg ccttgaccag gcatttccgt taatgatgaa gcaacttgag
     7861 ctgatgctga ccagtggaga gcttaaccct cgccacccac actgcgtcac gctttaccac
     7921 aatggactca cctgtgaagc cgatacacta ggctcctgtg gttatgtcta cattgctatc
     7981 tatcctgagc aaactgagcc gcagtaaatc cccgcttgtc ctcttaaact cacagagcaa
     8041 acatcatgca aactatatca tcacacccga cacgggcgac tcagccctgc ctgtcacccg
     8101 ttgaaatctg gcagcggtta ctgacttgtc tgttgtcgca gcactatggt ctgacgttga
     8161 atgacacacc gttcagtaat gaaaccacca tactggaaca cattgatgct ggagtatcgc
     8221 tgtgcgatgc ggtgaacttt cttgttgaaa aatatgaact ggtaagaatt gactgtaatg
     8281 attgctctgt catggagaag tcaccgttca tcaccagtat cgatattcta cgtgcccgga
     8341 aagcctccgg tctgatgaaa cgcaacagtc acaaaactgt taccagggta acggcaggtc
     8401 gacttcagga gctataagct atgggaagtc aattaatgtt gatatcgaca acattgatac
     8461 aatgctgtcc aatgtaggga aagctaacag taaccagatg atgaggagtt cgcgaaggct
     8521 aaagccagct tctcatcttt atctgtatca tctactcata ggggaatttt gttcacttgg
     8581 ctttgccctg attcgagtcc cgaatccaat gaattaatgt gttggtatc
//
LOCUS       DAZUDJ010000126         8539 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.128, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000126 DAZUDJ010000000
VERSION     DAZUDJ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8539
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.128"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            144..1325
                     /locus_tag="ACHY1N_004696"
     CDS             144..1325
                     /locus_tag="ACHY1N_004696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046864.1"
                     /translation="MPVRLNTIPDAESYPAPPARIKWLSALLLMLSVGVAITSLFASD
                     ELAKNGPHFWGLACGVPAFIWSLVASVRWLFFITQYIRADAWNKRREEVILQETRRGR
                     RALQILSFSVQTALNGDSVAETTTAFLARQQVLNTYADLRGEDTVRRSVIPVLTNKPV
                     TGRLSEIISRLFIDIRPQLFLLPPDFHINVLLEIDAPLSGASVRTIWQDEWQKAGLPE
                     ARLFSAPEPGLAAVDDWLDNFIQEKAVLLVISVYLEPKTPERTAESSTALTPLALLHR
                     PERITDTEMMASGIAQALDWMPVQPDAISGIWTAELDREQRTALLSLNQPFTQEALMY
                     ELDAFLGRSGPAAPWLSVAAATLAAIQSQHPQLTLSGVQGGHYSWATVVSPFVSPQEA
                     S"
     gene            1382..4708
                     /locus_tag="ACHY1N_004697"
     CDS             1382..4708
                     /locus_tag="ACHY1N_004697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImcF-related family protein"
                     /protein_id="HFS4046865.1"
                     /translation="MTVAVVVALCTFIHRKPALLGVEPGSSQQMYWMAGVIAAGVVFL
                     IIMGVYHLLNRHAAVQNFELRRQLAAGDDYRAVTTKKADSRHPAMVELAAFLRDRYGP
                     FWRRNVRLLLVTGEPEQAEAIAPGLTGQHWLEGDHTVLIYGGRPSAEPDVTLLTALKK
                     LRRSRPLDGIIWALTEEQSRQTAQLDKGWRELINGGKRLGFQAPLYLWQVCDNGDYQA
                     GRPLQSVGCLLPERCTPEQLTAMLEAHTLPLTEQGMSQLLADNRHDFLLRLAHTLAER
                     GIAHWQSVLKPLLAGGAFSSLRLRGLMFSPPLTAVPEAAPHAWLPSQVWAGVTGDNAR
                     GRAVGFPWLRAALMSAVCVLAIWGAGMTTSFFANCALVQETGIQTARALDTRLPLAEQ
                     LVALHTLQGELERLQYRIREGAPWYQRFGLERNQQLLAAAFPGYAQAANRLVRDVAVD
                     HLQQQLNAFVALPPNSPQRTATGEQRYKQLKALLMTSRPEKADAAFFSTTLMADSLRY
                     ENIPEGVQQSVFPSLLTFWMANLPEHPQWKTSPPPELTGAVRKILLRQIGVRNAENTL
                     YQNVLQQVSRNYADMTLADMTGDTLTESLFSTEQTVPGMFTRQAWEGQVREAIEQVVT
                     ARHEEIDWVLSDRQQDTSADISPDTLRNRLTSRYFTDFTGSWLAFLNSIRWKKEDSLS
                     GILDQLTLMADARQSPLIALTDTLAWQAAAGRENRGLSDSLAKSAQELFNGKEKTPQQ
                     SREGDVPVGPLDKTFAPLLRLLGDKAGGGDSQLSLQTYLTRVTRVRLKLQQVTNAPDP
                     QEMTQQLAQTVLQGKTVDLTDTRDYGRLIAASLGEEWSGFGQALFVRPVEQSWRQVLT
                     PAADSLNRQWQRAIVSHWNQDFAGRYPFKASQNDASLPLLAQYLRDDGRINQFIAANL
                     SGVLKREGRYWVADAMNTQGLTVNPDFIRALNRLRDVADTAFASGDAGIHFELQAKPA
                     RDVMKTHLVIDGQELEYFNQKERWQRFNWPDEQWQPGASLSWTSTQAMERILADYRGS
                     WSLIRLLEQAQVTPVDSSTFKVVWKAQDGLPLNYLLRVEQGKGPLALLELKNFRLPGQ
                     VFLTGRSMKDAEEYGEDADE"
     gene            4701..6311
                     /gene="tssA"
                     /locus_tag="ACHY1N_004698"
     CDS             4701..6311
                     /gene="tssA"
                     /locus_tag="ACHY1N_004698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssA"
                     /protein_id="HFS4046866.1"
                     /translation="MSELLQKLTRSCFVDRDALDVARTQAALWQTWLLPVTANTPVGE
                     DPGYHDDFLRIRDEMNKLSGADTDLICQLAESLLLTQAKDVRIATYYIWARLHRDGER
                     GLAEGLALLTGLVERFGTQLLPSRPASRKMALEWLAGEKMLDSLARYPEVAKEDFANI
                     VAALSQLTVSFTAWPEDQHSPSLMLLINALESRLAQSGGMNAVVPQNSSSVPAPSSPV
                     DAPQVQTITSGRDLLDQAKVLARYLNEQPQGWLSAHRLMKTLRWDTVHELPPDVDGKT
                     RLAPPRTESRNQLKRLYAQQNWTELLEQADLMFSTGVSHFWLDIQWYLHQALTKAGAP
                     WDRWTAVIRQDLALLLERLPGLENLAWNDDTPFADEVTRNWIAQQVMMREDGAWLAGK
                     AAVPTDDATNDVLALEPEALEMADSQGVEAALGWIQTRPGITTARQRLLLRLLMARVA
                     EQYGKNEMALLLLEELDTAAQGLTLTQWEPDLLFEVKARQLKLLRLRAHRYADKALLN
                     RKMEILLGTLVTIDPVRAAVLCDTQHKD"
     gene            6317..7735
                     /locus_tag="ACHY1N_004699"
     CDS             6317..7735
                     /locus_tag="ACHY1N_004699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001402492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
                     /protein_id="HFS4046867.1"
                     /translation="MGTGYFLVRGDKTTCGGKIIGGADDHTIMGIPQARDMDRVTCGR
                     YPGMFIIVGGVPETDIHGRLMAGTLDSQSSCPCKARFIASMMDDTYETDDGGSEAEQH
                     AQSAKKDLTSGSDSSSDDVKLDYRIKLSGNKILTPLNIPDYKEMISGGSTKNTEKIDF
                     TITNKGDEAEGLSLEVLDGNEVIYSEQQTGKYFDKGEHAWQWDGYSNQGILDTTKLKS
                     KSLLVRLIALCGDMMIKVDYPLHNSPEEQKWVDVKVDRKQKTVDIIWRLAVSDGGIKG
                     SNPKLSPVPYNDLVNLTKNGVEFYWSRNGSRGGGIGENIVTAIGVFKVNVKAEINITP
                     SMRTFSLISSLDPDFQASVSLSGFEKIYYNYGDSYKDIQDELQALLDANNRYKWDSAH
                     EMGHKVLDEYGEGSSPDYSWTHKGTSTLMQKTIPGNVMPAQGEIDVMKYGKYRPDMYT
                     RLVAADEDVQGLIWLSRIKFDD"
     gene            7728..8150
                     /locus_tag="ACHY1N_004700"
     CDS             7728..8150
                     /locus_tag="ACHY1N_004700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046868.1"
                     /translation="MTRVVIALLFLAGCTSQMKYSNVVRIRNVCSSDINVFIPEYVFG
                     GNVIKQHHIYLPVNGIDVLSYFYTENINDGFQYEEAFTVNKDSSGNFDYPFVILSSGR
                     EKKFGKNDLIELSRDISTKDDKKHGVVKYMIDSQDICP"
BASE COUNT         2073 a         2170 c         2409 g         1887 t
ORIGIN      
        1 agagcatact catcagataa tctaccatca aaagatggtt acatgatttt tgcattaaat
       61 aaataaaatg actctataga taactttaaa tttcacttgg ttattaactt ctgtccgata
      121 atgcaaaata aagggatgta ctgatgcctg tccgacttaa taccattccc gacgcagaat
      181 cctatcccgc accgccagcc cgcattaaat ggctgtcagc cttattactg atgctgtctg
      241 ttggtgtggc aataacctca ttattcgcca gcgatgaact ggcaaaaaac ggcccgcatt
      301 tctgggggct ggcctgcggt gtgcctgcct ttatctggtc gctggttgct tcagttcgct
      361 ggttgttttt tatcacgcag tacattcggg ctgatgcctg gaataagcgc cgggaagagg
      421 tgattttgca ggaaacgcga cggggacgac gggcgttgca gatacttagt ttttccgtac
      481 aaaccgcgct gaatggtgat tccgttgcag aaactacaac agcatttctg gcgcgtcagc
      541 aggtgttgaa tacttacgct gatttgcgcg gagaagatac tgtgcgtcgc agtgtcattc
      601 ccgtattaac caataaaccg gttaccgggc gtttatccga aattatttcc cgccttttta
      661 ttgatatcag accgcaattg tttctgctgc cccctgattt tcatatcaac gtactactgg
      721 aaattgatgc gccgctttca ggggcctccg tgagaactat ctggcaggac gaatggcaaa
      781 aagccggact cccggaagcc cgtctgtttt ctgccccgga gccggggctg gccgccgtgg
      841 acgactggct ggacaacttt attcaggaaa aggccgtact gctggtgatt tccgtgtatc
      901 tggaaccgaa gactccggaa cggacggcag aatcctccac cgcgctgacg ccgctggccc
      961 tgctgcatcg tcctgaacgt atcacagata cagagatgat ggcgtcaggc attgcacagg
     1021 cgctggactg gatgccggtg cagccagatg ccatatccgg catatggact gccgaactgg
     1081 acagggaaca gcgtaccgcg ttgttatccc ttaaccagcc gtttactcag gaagccctga
     1141 tgtacgagct ggatgccttt ctggggcgct ccggaccggc agcgccgtgg ctgtccgtcg
     1201 ctgcggcaac gctggcggca atacaatcac aacaccccca actaacgctc agcggcgttc
     1261 agggcgggca ttattcatgg gcgaccgtgg tgtcgccatt cgtttcccca caggaggcat
     1321 catagtggtt ccgggattaa accgtctccg gccccgttct gtttcagggc ctgccatcgt
     1381 catgaccgtg gctgttgtgg ttgcgctttg cacgtttatt caccgtaaac cggcattgct
     1441 gggcgttgaa ccgggtagct cacagcaaat gtactggatg gctggcgtga ttgccgcagg
     1501 cgtggtcttt ttgattatca tgggggttta tcatctgctg aaccgccacg ctgccgtaca
     1561 aaactttgaa ctccgcagac aacttgccgc cggagatgac tatcgtgcgg tgacgacaaa
     1621 gaaagccgac agccgtcatc cggcaatggt ggaactcgcc gccttcctgc gcgaccgcta
     1681 cggtccgttc tggcggcgta acgtccgcct gctgctggtg accggcgagc ctgaacaggc
     1741 agaagccatc gcgccggggc tgaccgggca acactggctg gagggcgacc acacggtgct
     1801 gatatatggc ggcaggccat cagcggagcc tgatgtcaca ctgctgaccg ccttaaaaaa
     1861 actgcgccgc agccgtccgc tggacggcat catctgggcg ctgacagaag aacagagccg
     1921 ccagacagcg caactcgaca aaggctggcg cgaactgata aacggcggta agcgactcgg
     1981 ttttcaggcc ccactctatt tgtggcaggt ctgtgacaac ggtgattatc aggccggacg
     2041 ccccctgcaa agcgtcggct gcctgctgcc ggaacgctgc accccggaac aactgaccgc
     2101 catgctggaa gctcacaccc tgccgctgac ggaacagggc atgtcgcaac tgctggctga
     2161 taaccgccat gattttctgc tgcgtctggc ccataccctt gcagagcggg gtatcgctca
     2221 ctggcaaagc gtcctgaaac cgctgctggc aggcggcgca ttctcttccc tgcgcctgcg
     2281 tggtctgatg ttcagcccgc cgcttaccgc cgtaccggag gccgcacctc atgcgtggct
     2341 gccgtcacag gtctgggcgg gcgtgaccgg cgataacgca cgggggcgtg cagtgggctt
     2401 tccgtggcta cgcgccgcgc tgatgtccgc tgtctgcgtg ctggcaatat ggggggccgg
     2461 aatgacgacc tctttcttcg ccaactgcgc tcttgttcag gaaaccggta tccagacggc
     2521 gcgggcgctc gatacccgcc tgccgctggc agaacaactg gtggcgctgc ataccctgca
     2581 gggcgaactg gaacgcctgc aatatcgtat ccgcgaaggt gcgccgtggt atcagcgttt
     2641 tggccttgaa cgtaaccaac aactgctcgc cgccgccttt cccggctatg cgcaggcggc
     2701 aaaccggctg gtgcgcgacg tggccgttga ccatctgcaa cagcaactga acgcctttgt
     2761 cgccctgccg cccaacagtc ctcagcgtac cgccaccggt gaacaacgct ataagcagct
     2821 taaggcattg ctgatgactt cccgcccgga aaaggccgac gctgcctttt tcagtaccac
     2881 gctgatggca gacagcctgc gctacgagaa tatcccggaa ggtgtgcagc agagcgtgtt
     2941 tccgtcactg ctgaccttct ggatggcgaa cctgccggaa cacccgcagt ggaaaacctc
     3001 gccgccaccg gaactgaccg gcgcggtgcg taaaatcctg ctgcgccaga ttggtgtgcg
     3061 taatgccgaa aacactctct accagaacgt actgcaacag gtgtcccgca actacgccga
     3121 tatgacgctg gcggacatga ccggggatac cctcaccgaa tctcttttca gtacggaaca
     3181 gacggtgccg gggatgttca cccgtcaggc gtgggaagga caggtcaggg aagccatcga
     3241 gcaggtggtg acggcgcggc acgaggaaat cgactgggtg ctcagcgacc gccagcagga
     3301 tacctctgcg gatatatcgc cggatacgct gcgtaaccgt ctcacctcac gctactttac
     3361 cgacttcacc ggaagctggc tggcgtttct caacagcatt cgctggaaaa aggaagactc
     3421 gctctccggc attctcgacc agctgacact gatggccgat gcccgtcagt cgccgctgat
     3481 tgcgctgacc gataccctcg cctggcaggc ggcggcaggc agggaaaacc gtggcctgtc
     3541 agactcgctg gcgaaatcgg cacaggaact gtttaacggc aaggagaaaa cgccgcagca
     3601 atcccgtgaa ggcgacgtgc ctgtcgggcc gctggataaa accttcgctc cgctgctgcg
     3661 gttgctgggc gataaagccg gaggcggcga cagccagctg agtctgcaga cctacctcac
     3721 ccgcgttacc cgtgtgcgtc tcaaactgca acaggtgacc aacgcccccg acccgcagga
     3781 aatgacgcaa cagctggcac agacggtact gcagggcaaa accgttgacc tcaccgacac
     3841 ccgcgactac ggacggttaa tcgccgccag tctgggcgag gaatggagtg gcttcggtca
     3901 ggcgctgttc gtccgcccgg tggagcagtc gtggcggcag gtgctgacgc ctgcggcgga
     3961 cagcctgaac cgccagtggc agcgggcgat tgtcagccac tggaatcagg acttcgctgg
     4021 tcgctacccg ttcaaagcct cacagaacga tgcctccctc cccctgctgg cgcagtatct
     4081 gcgcgatgac gggcgcatca accagtttat tgccgccaac ctttccggcg ttctgaaacg
     4141 tgaaggccgc tactgggtgg cggacgccat gaacacgcag gggctgacgg tcaacccgga
     4201 ctttatccgc gccctgaacc gcctgcgcga cgtggctgac accgcctttg ccagcggcga
     4261 tgccggaata cattttgaac tgcaggcaaa accggcccga gacgtgatga agacacatct
     4321 ggtgattgac gggcaggaac tggagtattt caaccagaaa gaacgctggc agcgtttcaa
     4381 ctggccggat gaacagtggc aacccggcgc atcgctgagc tggaccagta cgcaggcgat
     4441 ggaacgcata ctggcggatt accgggggag ctggagcctt attcgcctgc tggaacaggc
     4501 gcaggtgaca ccggtggaca gcagcacctt taaagtggtg tggaaagcgc aggacggcct
     4561 gccgctgaat tacctgctgc gggttgaaca gggtaaaggg ccgctggcgc tgctggaact
     4621 gaaaaacttc cgcctgccgg gacaggtatt tctgaccggc aggagtatga aagatgcgga
     4681 agaatacggg gaagacgccg atgagtgaac tgttgcaaaa gctgacccgt agctgttttg
     4741 tcgaccggga tgcactggat gtggcgcgaa cacaggcagc gctgtggcag acatggctgc
     4801 tgccggtgac ggcaaatacg ccggtcgggg aagaccccgg ctaccacgac gatttcctgc
     4861 gtatccgcga cgagatgaac aaactttccg gcgcggatac ggacctcatc tgccagcttg
     4921 ccgaatccct gctgctgacg caggcaaaag acgtgcgcat cgccacttac tacatctggg
     4981 cgcgactgca ccgcgacggt gagcgcggac tggctgaggg gctggcgcta ctgaccggac
     5041 tggtggaacg cttcggtacg caactgctgc cctcgcgacc ggccagccgg aaaatggcgc
     5101 tggagtggct ggcaggggaa aagatgctcg acagtcttgc ccgctacccg gaagtggcaa
     5161 aagaggattt tgcgaacatt gttgctgccc tcagtcagtt gacggtttcc ttcactgcat
     5221 ggcccgaaga ccagcattcc ccctccctga tgctgctgat taacgcgctg gaatcacgtc
     5281 tggcgcagtc gggcgggatg aacgcggtgg tgccgcaaaa cagcagcagc gttcctgcac
     5341 cgtcatcccc ggtggatgcg ccacaggtac agaccatcac ctccgggcgt gacctgctcg
     5401 accaggcgaa agtgctggcc cgttatctga acgaacagcc gcagggctgg ctttcggcgc
     5461 accggctgat gaaaaccctg cgctgggaca cagtgcatga actgccgccg gatgtggacg
     5521 gcaaaacccg gctggccccg ccgcgcaccg agtcacgcaa ccagcttaag cggctgtatg
     5581 cgcagcagaa ctggacggaa ctgctggagc aggccgacct gatgttcagc accggcgtca
     5641 gccatttctg gctggatatc cagtggtatc tgcatcaggc gctgactaag gcgggcgcac
     5701 cgtgggacag gtggacagcc gttatccgtc aggacctggc gctgctgctg gaacgtctgc
     5761 cagggctgga aaatctggca tggaacgacg acacaccgtt cgccgacgag gtgacgcgca
     5821 actggatagc gcagcaggtc atgatgcggg aagacggcgc atggcttgca gggaaagccg
     5881 ctgtaccgac agacgacgcc acaaatgacg tactggcgct ggagccggaa gcactggaga
     5941 tggcagacag tcagggcgtg gaagcggctc tgggctggat acagacccgt ccgggcatca
     6001 ccacggcacg ccagcgcctg ttattgcgac tgctgatggc gcgggtggcg gaacagtacg
     6061 gtaaaaacga aatggcgctc ctgctgctgg aagaactgga taccgccgca caggggctga
     6121 cactgacgca gtgggagccg gacctgctgt ttgaggtaaa agcccgacaa ctgaaactgc
     6181 tgcgcctgcg ggcgcaccgc tatgcggata aagccctgct gaaccgaaaa atggaaatcc
     6241 tgctgggaac gctggtgaca atcgatccgg tacgggcagc ggtattgtgt gatacgcaac
     6301 ataaggactg atggcaatgg gaacaggcta ctttctggtc aggggggaca aaaccacctg
     6361 cggcgggaag attattggag gcgcggacga ccatacgatc atgggtatcc cacaggcacg
     6421 ggatatggac cgggtcacct gcggcagata tccgggaatg tttattattg tgggcggcgt
     6481 tcctgaaaca gatattcacg gcaggctgat ggcggggacg ctggacagcc agagcagttg
     6541 cccctgtaag gcacggttta ttgcgtcgat gatggatgat acgtatgaga cggatgacgg
     6601 gggaagtgaa gcggaacaac atgcgcagtc ggcgaaaaag gatctgactt ctggttctga
     6661 ttcatcctct gatgatgtaa aactggatta cagaattaaa ttatcaggta ataagatact
     6721 gacgccactg aatatacctg attataaaga aatgataagc ggtggtagta cgaagaatac
     6781 agaaaaaata gattttacta tcacaaataa aggcgatgag gctgaaggac tttctctgga
     6841 agtgcttgat ggtaatgaag tgatttacag tgaacagcag accggtaaat attttgataa
     6901 gggagagcat gcctggcaat gggatggcta cagtaatcaa ggcatactgg atacaactaa
     6961 gctaaaaagc aaatcactac tcgtaagact gattgcttta tgtggtgata tgatgataaa
     7021 agttgattat ccacttcata attcaccaga ggaacaaaaa tgggtcgatg taaaggtaga
     7081 cagaaaacaa aaaacagtag atataatatg gcgactggca gttagtgatg gagggataaa
     7141 aggaagtaat cctaagttat ccccagttcc ttataacgac ttggttaacc tgaccaaaaa
     7201 tggagttgaa ttttattggt ctcgaaatgg aagtcgcggc ggggggattg gtgaaaatat
     7261 tgttacagcg attggtgttt ttaaagtaaa tgtaaaggct gagataaata ttactccatc
     7321 catgcgaact ttttctttga tatcatcatt agatcctgac tttcaggcat ccgttagtct
     7381 atcaggattt gaaaaaatat attataacta cggtgatagt tataaggata ttcaagatga
     7441 attacaggcg cttcttgacg ctaataacag atataaatgg gatagtgctc atgaaatggg
     7501 gcataaagta ctcgatgaat atggagaggg ttctagccct gattattcgt ggactcataa
     7561 aggaacatct actcttatgc aaaaaacaat accagggaat gttatgcccg ctcagggaga
     7621 gattgatgta atgaaatatg gaaaatatcg tcctgacatg tatactcgat tggttgcagc
     7681 agatgaagat gttcagggat tgatctggtt aagcaggata aaatttgatg actagagtag
     7741 ttattgcttt attatttctt gccggatgta cttcgcaaat gaagtattcc aatgtcgtca
     7801 ggattaggaa tgtatgttcc tcagatatta atgtgtttat tcctgagtat gtttttggag
     7861 gtaatgttat taagcaacat catatttact tacctgttaa tgggattgat gttttgtctt
     7921 atttttatac tgaaaacatc aatgatggtt tccaatatga agaagcattc accgtaaata
     7981 aagatagctc gggtaatttt gattatccgt ttgttatctt atcatcagga cgtgaaaaaa
     8041 aatttgggaa aaacgatcta attgaattat ccagggacat ttcaacaaaa gacgataaga
     8101 agcatggggt tgtaaagtac atgatagata gtcaggatat ttgcccatag tatgattcat
     8161 atcataatca actgaaaaaa tgacattatt aatcatttgt gattttttga tactaccaag
     8221 tgaaatttga tgattagatt aatattctct tttttattat gcacactgtg tgctggatgt
     8281 ttatctcaac cattctattc ttgttccatt gtcatggtaa atacatgcaa agtatctatt
     8341 aacatttcga cagtcaataa ttcaacacat tatgatggta aggtaagaga taattttcat
     8401 cttgatatcg gagagcggaa gccaattgta tactttattt acacaggtag agagtcagat
     8461 gtttttaata aaaaccctgt aaatattgtt tctgaactta gtattttgat atctgatggt
     8521 aacaattcta aaactttat
//
LOCUS       DAZUDJ010000127         8203 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.129, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000127 DAZUDJ010000000
VERSION     DAZUDJ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8203
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.129"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(436..921)
                     /gene="sixA"
                     /locus_tag="ACHY1N_004701"
     CDS             complement(436..921)
                     /gene="sixA"
                     /locus_tag="ACHY1N_004701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0101006 - protein histidine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HFS4046869.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTTNGCDESRLMANWLKGQKVE
                     IERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVSAYLQALTNEGVAS
                     VLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGNGTFNWQMSPCNLKMAKA
                     I"
     gene            complement(1124..3268)
                     /gene="fadJ"
                     /locus_tag="ACHY1N_004702"
     CDS             complement(1124..3268)
                     /gene="fadJ"
                     /locus_tag="ACHY1N_004702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0004300 - enoyl-CoA hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008692 - 3-hydroxybutyryl-CoA epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0009062 - fatty acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HFS4046870.1"
                     /translation="MEMASVFTLNVRLDNIAIITIDVPGEKMNTLKAEFASQVRAIIK
                     QLRENKELRGVVFVSAKPDNFIAGADINMIGNCKTAQEAEALARQGQQLMAEIHALPI
                     PVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIG
                     VSTALEMILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELAKKDRPSSRPLPVRERI
                     LAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGEL
                     AMTPQSQALRSIFFASTDVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLP
                     VRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDKQLALISGTTDYRGFAHRDLI
                     IEAVFENLELKQQMVAEVEQNSAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSP
                     VEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIR
                     MLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVV
                     SSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGAQGQGRLSAPQVAERCVM
                     LMLNEAVRCVDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLA
                     TQYGSRFTPCERLVEMGARGESFWKTTATDLQ"
     gene            complement(3268..4578)
                     /gene="fadI"
                     /locus_tag="ACHY1N_004703"
     CDS             complement(3268..4578)
                     /gene="fadI"
                     /locus_tag="ACHY1N_004703"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003988 - acetyl-CoA C-acyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HFS4046871.1"
                     /translation="MGQVLPLVIRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMV
                     VGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLF
                     SRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWS
                     DGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLT
                     DGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     SDLTLIDMHEAFAAQTLANIQLLGSERFAREVLGRAHATGEVDDSKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE"
     gene            complement(4758..5042)
                     /locus_tag="ACHY1N_004704"
     CDS             complement(4758..5042)
                     /locus_tag="ACHY1N_004704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcZ/YiiS family protein"
                     /protein_id="HFS4046872.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFASRAEAEQTL
                     AALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR"
     gene            5414..6754
                     /gene="fadL"
                     /locus_tag="ACHY1N_004705"
     CDS             5414..6754
                     /gene="fadL"
                     /locus_tag="ACHY1N_004705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HFS4046873.1"
                     /translation="MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVNISGTSPSGRSLKADNIAPTA
                     WVPNMHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYR
                     LNNAWSFGLGFNAVYARAKIERFAGDLGQLVAGQIMQSPAGQTPQGQALAATANGIDS
                     NTKIAHLNGNQWGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLNRAFNNYG
                     LPIPTATGGATQSGYLTLNLPEMWEVSGYNRVDPQWAIHYSLAYTSWSQFQQLKATST
                     SGDTLFQKHEGFKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRF
                     WLSAGTTYAFNKDASVDVGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF"
     gene            7121..8179
                     /gene="yfdF"
                     /locus_tag="ACHY1N_004706"
     CDS             7121..8179
                     /gene="yfdF"
                     /locus_tag="ACHY1N_004706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YfdF"
                     /protein_id="HFS4046874.1"
                     /translation="MLPSISINNTSATYPESINENNNDEVNGLVQELKNLFNGKEGIS
                     TCIKHLLELIKNAIRVNDDPYRFNINNSSVTYIDIGSNDTDHITIGIDNQEPIELPAN
                     YKDKELVRTIINDNIVEKTHDINNKEMIFSALKEIYDGDPGFIFDKISHKLRHTVTEF
                     DESGNSEPTDLFTWYGKDKKGDSLAIVIKNKNGNDYLSLGYYDQDDYHIQRGIRINGD
                     SLTQYCSEKARNASAWFESSKAIMAESFATGSDHQVVNELNGERLREPNEVFKRLGRA
                     IRYNFQVDDAKFRRDNVKEIISTLFANKVDVDHPENKYKDFKDLEDKVEKRLQNRQTE
                     YQNEINQLSAPGVNFDDI"
BASE COUNT         2238 a         2065 c         1842 g         2058 t
ORIGIN      
        1 catccttaaa aaatacggaa taagtattta gaaaaaatag aaagtatatc aataatgaat
       61 atcaacagct taaaaaacaa acaatgaaca tataatgcga ttggcattta tccacttttg
      121 acaatataat atataaacac tatagccaga atttaatcaa gtttcaatta catcctgcct
      181 gattattcaa ctctattttc tctattatct gtattaataa atgacaatga gtgtcaaaca
      241 gacattattc atttcaacat gtaactttgg gcaaaatcaa gatacgcgca gaagaataat
      301 ttccgaatga atgtagaaag tgttttattt atagataagg agagtcttcg atagtagtga
      361 ggttgacaga tatccgctgc ctgatgagca attatgccca atgaatctac ctcattgggc
      421 ataatttgga acacatcaga tagcttttgc catcttcaga ttacacgggc tcatctgcca
      481 gttgaatgta ccgtttccgc tttcatcaag cgttacgctg gcaatggccg aggtggtaaa
      541 cataggcggc gtttcgcccg gacataactc ggcaaccaga tacccgacta acggtaagtg
      601 agagatcacc agtaccgaag caacaccttc attggtcaac gcctgcaaat aggcactgac
      661 cagaccaaca tcgccgcagg gcgttaactc cggcagaact tctgcactgg aaggcaggtt
      721 cagacaatcc cctacttctt ccagtgtttg ctcggctcgc aggaacgggc tcaccagaac
      781 gcgttcgatt tccacttttt gacctttcag ccagttcgcc atcaggcgag attcgtcaca
      841 accattagtg gtcagaggac gaacggaatc actggcggca tcgagggctg cgtcgccgtg
      901 acgcatgata aaaacttgca tattgcaccg cttttgttaa ccagattcgc ccgttttctt
      961 tcatctgaaa ccagagaaag aaaacggtgg ccggcattgt gccttatcca ttcaccgaat
     1021 gaaacgctgt tttttacctc aatggcgtaa gtatagtcaa tatgcgttta cattttgacc
     1081 aacactccgc cattcagcgc ggattcatat agctttgacc ttcttattgc aggtcagttg
     1141 cagttgtttt ccaaaaactt tccccacgcg cgcccatctc gaccaaacgc tcgcaagggg
     1201 taaaacggga accatactgc gtggcaagtc gttgcattat tgcaaccact tcgcccgcgc
     1261 cgagagaatc gatatagcgg aacggtccac cgagaaatgg cggaaaacca atgccaaata
     1321 ccgcaccaat atccccgtca cgcacgctac ggataacctg ctcatcaaca caacgtactg
     1381 cttcattcag catcaacatc acacaccgtt cagcaacctg cggtgcggag agtcgcccct
     1441 gcccttgtgc gccaatgagc gggtaaatgg cgggatcgac ctgttttttg cttttacgcc
     1501 ctttctgacc ataaagatag aaaccccgac cattttttct gcctttgcga tcgtcgttca
     1561 aaattgaaga aacaacattt gcaggcgcgc taaaacgttc tccataagcg gcttccagta
     1621 caggaataat tttagtcccg gtgtcgattc ctacctcatc caaaagttgg attggaccta
     1681 ccggaaaacc aaatttcact agcgcggcat caatgtgctc tacccgttca ccttcggtca
     1741 gcatgcggat agcttcatta atgtaaggcg ctaagatgcg attgacgtaa aacccggctt
     1801 tgtcacgcac gacaatgggc gttttgccct gttttttcgc cagttttacc gtagtggcga
     1861 tggtttgcgc tgatgtaccc gcatgaggaa taatctccac cagcggcatt ttttccaccg
     1921 gactgaagaa atgcaggccg ataacttgct caggtcgcgt ggcgtgagcg gcgatatcac
     1981 caatcggtaa agatgacgta ttcgaagcaa agatggtatg agcggcgcta ttttgctcaa
     2041 cttccgccac catctgttgt ttcaattcga gattttcaaa caccgcttca ataatcagat
     2101 cgcgatgggc aaagccgcga tagtccgtcg ttccggagat taatgccagc tgtttgtcac
     2161 gttcgctggc tttgagatga cgacggcgaa ctttgccctc cagctgatcc caactgtact
     2221 tcagcgcatg atttatgccc tgcgggttga tatctttaat tctgaccgga agccccgctt
     2281 tacaagcagt gacataagca ataccgccgc ccatcaagcc accacctaaa attcccacgc
     2341 tgtttaatgg cgcaggcggt gcatcactac cgggatcttt cttcacgtcc gtactggcaa
     2401 aaaagatact acgcagcgcc tgcgattgtg gcgtcatcgc cagttcgcca aacgcccgag
     2461 cttcggcgtc ataaccgctg ctggtgccct gcgctaatcc cgtttcaaca acctccagga
     2521 tgcgttctgt cgccggataa ttgccttgag ttttgtgttc tgttttcttg ccgaccattt
     2581 tgaacagcag cgcacgacct aacggccccg ccagaatacg ctcgcgtaca ggtagagggc
     2641 gggaagatgg gcgatccttc ttcgccagct caacagcgac ttccagcaaa atggagtgcg
     2701 gaacaacgtc atccaccagc cccagcttta atgcctgttt cgcccgaagt tgttttccgg
     2761 tgaggatcat ctctaatgct gtgctgacgc ctatcagacg cggtaaacgc tgggtgccgc
     2821 ctgaaccggg taacaatcca agttgtactt caggcaaacc gagcaccgtt ttaggatcgt
     2881 cagtacaaac gcgaccgtgg cacgccagcg ccaactccag cccaccaccc aggcaagcgc
     2941 catgaatagc cgcgataacc ggaatgggca aagcatgaat ctccgccatc aactgttggc
     3001 cctgccgcgc cagtgcttcc gcttcttgcg ccgttttgca gttgccgatc atgttgatgt
     3061 ctgcgccagc aatgaagttg tccggtttag cggagacaaa caccacgcct cgcaactctt
     3121 tgttttcacg gagttgctta ataatggcgc gcacctgcga ggcaaactcc gccttcaggg
     3181 tattcatttt ctcacccggt acgtcgatgg tgatgatagc aatgttgtcc agacgaacat
     3241 taagagtaaa cactgatgcc atttccatta ttccgcctcc agaaccattg ccgcgccaag
     3301 cccaccggca gcacaggcgg taactaaacc aaatccaccg ccgcgacggc gaagttcatg
     3361 caatgtctgg gtaatcatcc gcgcgccggt cgccgcgaag ggatgcccgt aagcaatcga
     3421 accgccaagc acgttaaatt tgctatcgtc cacttcgcca gtggcatgtg cacgccccag
     3481 tacttcacga gcaaaacgtt cactacccag caactgaata ttcgccagtg tctgagctgc
     3541 aaaggcttcg tgcatatcga tcaatgtcag atcgctcatt gtcaaaccgg cacgttccag
     3601 cgccagcggt gttgaccagg ccggaccgag caacatgtcc tgccagacat caatcgcagt
     3661 aaatgcgtag ctgcgcagat accccagcgg caccagccct aattctttcg cccgggattc
     3721 agtcatcagg atcaccgccg ctgcgccatc ggtcagcggc gtactgttcg ccgccgttac
     3781 cgttccgtgt ttgcgatcaa acgccgggcg cagctttgcg taatcggcaa gcgaggaatt
     3841 accgcgaata ttgttgtctt cgacaagcgg ttgtttataa ggagggataa aggcagtcat
     3901 cacctcttct ttgagtttac cgtctgacca cgcctgagcg gcacgctgat gcgaacggtg
     3961 cgctaatgca tcttgctgtt ctcgggtgat gccgtaggtt ttcgccattt gttcggcggt
     4021 gtcgcccatc cgcaagccag tagaatattc tgctaccgca ggcggtacgg gcattaagtc
     4081 gcgcaaacgc aggcgagaga agagtttcag tcgctggctc atggttcgag ctttgttgac
     4141 atcaaccagc acgcgcgcca gttttttact gacgccaatt ggcaatacgg aagaggaatc
     4201 tgccccaccg gcaatccccg ctcggatagt tcccgccatc aggctttctg cgacgtttgc
     4261 aaccgcctgg aaactggtag cgcaagcgcg gctgacgctg taagcatcgg tatgcacatt
     4321 cattccggta ccgagaacaa tttcacgcgc aatgttgggg gcttcaggca tttgtacgac
     4381 ctgaccaaag accagctgtt caatcacttc agcggggatc tcgctgcgtg ccagcagttc
     4441 gcctaccacc atcttcccta aatcaaccgc gggaatgcca tgaaaagccg tcgcctggcg
     4501 ggcaaaaggc gtacgtaaac cgctaacaat ggcgatacga tcgccctggc ggataaccag
     4561 cggtaaaacc tgacccataa cactcccctg taaaaaaata aataaagtgg tctgacctga
     4621 tcatagtctt aaccattttt ttacatttag ccaagcggag aaaaaagaaa gtgggagcta
     4681 tgacacagtg aagacaggag aaagaaaaga aaacgcccct gccagcaact gacaggggcg
     4741 aacgtacccg agaggaatta acgcagaccc agctggaaga tcagcatttc agcttcgcag
     4801 gcaaaagtga aatcgatatc caggcgcaca ccgtcagact cttcagtgaa agtcggggtg
     4861 attttgcacg gttcggattc cacgctacgg gctttttcag tcagcgccgc cagcgtttgt
     4921 tctgcttctg cgcggcttgc aaacacgcgg ctgtaagacg cggtgcagtc ggagttgtcc
     4981 ataatggtgc caacatccat acagcagcaa accggggttt catcagcact acatttactc
     5041 atcgttgatt tcctctgtat gtgcacccaa ggtgccagat aaacgttgtg gatattttac
     5101 gcttccggaa agtgctgctc cagttgttaa ttctgcaaaa tcggataagt gaccgaaatc
     5161 acacttaaaa atgatctaaa acaaaattca cccgaatccg cgagtgcgca acctccaaat
     5221 tttgccagct ggatcgcgtt tcttagatca tatttgaaaa aagatggaaa catacttgca
     5281 acattccagc tggtccgacc tatactctcg ccactggtct gatttctaag atgtacctca
     5341 gaccctacac ttcgcgctcc tgttacagca cgtaacatag tttgtataaa aataaatcat
     5401 tgaggttatg gtcatgagcc agaaaaccct gtttacaaag tctgctctcg cagtcgcagt
     5461 ggcacttatc tccacccagg cctggtcggc aggctttcag ttaaacgaat tttcttcctc
     5521 tggcctgggc cgggcttatt caggggaagg cgcaattgcc gatgatgcag gtaacgttag
     5581 ccgtaacccc gcattgatta ccatgtttga ccgcccgaca ttttctgcgg gtgcggttta
     5641 tattgacccg gatgtgaata tcagcggaac gtctccgtct ggtcgtagcc tgaaagccga
     5701 taacatcgcg cctacggcat gggttccgaa catgcacttt gttgcaccga ttaacgacca
     5761 atttggttgg ggcgcttcta ttacctctaa ctatggtctg gcaacagagt ttaatgatac
     5821 ttatgcaggc ggctctgtcg ggggtacaac tgaccttgaa accatgaacc tgaacttaag
     5881 cggtgcgtat cgcttaaata atgcatggag ctttggtctt ggtttcaacg ccgtctacgc
     5941 tcgcgcgaaa attgaacgtt tcgcaggcga tctggggcag ttggttgctg gtcagattat
     6001 gcaatctcct gccgggcaaa ctcctcaagg gcaagcattg gcagctaccg ccaacggtat
     6061 cgacagtaat accaaaatcg ctcatctgaa cggtaaccag tggggctttg gctggaacgc
     6121 cggaatcctg tatgaactgg ataaaaataa ccgctatgca ctgacctacc gttctgaagt
     6181 gaaaattgac ttcaaaggta actacagcag cgatcttaat cgtgcgttta ataactacgg
     6241 tttgccaatt cctaccgcga caggtggcgc aacgcaatcg ggttatctga cgctgaacct
     6301 gcctgaaatg tgggaagtgt caggttataa ccgtgttgat ccacagtggg cgattcacta
     6361 tagcctggct tacaccagct ggagtcagtt ccagcagctg aaagcgacct caaccagtgg
     6421 cgacacgctg ttccagaaac atgaaggctt taaagatgct taccgcatcg cgttgggtac
     6481 cacttattac tacgatgata actggacctt ccgtaccggt atcgcctttg atgacagccc
     6541 agttccggct cagaatcgtt ctatctccat tccggaccag gaccgtttct ggctgagtgc
     6601 aggtacgact tacgcattta ataaagatgc ttcagtcgac gttggtgttt cttatatgca
     6661 cggtcagagc gtgaaaatta acgaaggccc ataccagttc gagtctgaag gtaaagcctg
     6721 gctgttcggt actaacttta actacgcgtt ctgataacgc gttcgcctgg ataaagtcac
     6781 ctgcatagca ggtgacttta actcccccac ttcaccgaaa gtagtgtcct cattgcttac
     6841 ctcctgagtt ttgcaaacag cctgttggca gcttgccctt tcaaatcagt aagtggtatt
     6901 cacagacaaa cctgaaggga aatgcatatt ttcaagcgtt ctgctcgtcc ttctcaaaga
     6961 gtttactttt ctgaatttcc aggatactcc cccccccctg gctattgtgc gctcatacac
     7021 tcaaattaaa gataggttct aaataaatga gcgttttttg atagtctatt tcattaggta
     7081 atatatattt gtaacaaatc aatcaaaatg gaataaaatc atgctaccat ctatttcaat
     7141 caacaatacc agcgcaactt acccagaatc cattaatgaa aataacaatg atgaagttaa
     7201 tggattagta caagagctca aaaacctttt taatggtaag gaaggaataa gcacctgtat
     7261 taaacatcta cttgagctta taaaaaacgc catacgagta aacgacgatc cttatagatt
     7321 taatattaat aattcctcag ttacttatat tgatattggc tccaatgata cagaccatat
     7381 tactattggt atcgacaacc aagaaccaat agaattacct gcgaactata aagacaaaga
     7441 actcgtccgt actatcatta atgacaacat agttgagaag actcatgata tcaataacaa
     7501 ggaaatgatc ttcagcgcat taaaagaaat atatgatgga gatcctggtt ttatcttcga
     7561 taagatatca cacaaactca gacatacggt aacggaattt gatgagagcg ggaatagcga
     7621 accaacggac ttatttacct ggtacggtaa agataaaaaa ggcgactctc tcgctattgt
     7681 aattaaaaat aaaaacggaa atgattactt atctctcggt tactacgatc aggacgacta
     7741 ccacattcaa agaggaattc gtattaatgg tgatagtctc acccaatatt gtagtgaaaa
     7801 agccaggaat gcttcagcgt ggtttgaaag cagtaaagct atcatggcag aatcatttgc
     7861 aacaggttcc gatcatcagg ttgtaaacga gctcaacggg gaaagactga gagaacctaa
     7921 cgaagttttt aaacgtttag gtcgagcaat aagatataat tttcaagtgg acgatgcaaa
     7981 atttagacgc gataatgtaa aagaaataat ttctacttta ttcgctaaca aagttgacgt
     8041 tgaccatcct gaaaataaat acaaagactt taaggatctc gaagataaag ttgaaaaaag
     8101 gcttcaaaat cgccagacgg aatatcaaaa tgaaattaat caactatctg cgccaggtgt
     8161 taattttgat gatatttaaa attatttttc cagttttttg att
//
LOCUS       DAZUDJ010000128         7905 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.130, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000128 DAZUDJ010000000
VERSION     DAZUDJ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7905
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.130"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            134..1414
                     /gene="wcaK"
                     /locus_tag="ACHY1N_004707"
     CDS             134..1414
                     /gene="wcaK"
                     /locus_tag="ACHY1N_004707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis pyruvyl transferase
                     WcaK"
                     /protein_id="HFS4046875.1"
                     /translation="MKLLILGNHTCGNRGDSAILRGLLDAINILNPHAEVDVMSRYPV
                     SSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVLRRRYQHQVLLSRVTDTGKLRNI
                     AIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCTFMAKKPLFMIGHSVGP
                     FQDEQFNQLANYVFGHCNALILRESVSLELMKRSNITTAKVEHGVDTAWLVDHHTEDF
                     TASYAVQHWLDVAAQQKTVAITLRELAPFDKRLGTTQQAYEKAFAGVVNRILDEGYQV
                     IALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLEMGKILGACELTVGT
                     RLHSAIISMNFSTPAIAINYEHKSAGIMQQLGLPEMAIDIRHLLDGSLQAMVADTLGQ
                     LPALNARHNEAVSRERHTGMQMVQSVLERIGEVK"
     gene            1411..2631
                     /gene="wcaL"
                     /locus_tag="ACHY1N_004708"
     CDS             1411..2631
                     /gene="wcaL"
                     /locus_tag="ACHY1N_004708"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaL"
                     /protein_id="HFS4046876.1"
                     /translation="MKVGFFLLKFPLSSETFVLNQITAFIDMGFEVEIVALQKGDTQN
                     THAAWTKYNLAARTRWLQDEPTGKVAKLRHRASQTLRGIHRKNTWQALNLKRYGAESR
                     NLILSAICGLVATPFHADVFIAHFGPAGVTAAKLRELGVIRGKIATIFHGIDISSREV
                     LNHYTPEYQQLFRRGDLMLPISDLWAGRLQKMGCPREKIAVSRMGVDMTRFSPRPVKA
                     PATPLEIISVARLTEKKGLHVAIEACRQLKEQGMAFRYRILGIGPWERRLRTLIEQYQ
                     LEDVVEMPGFKPSHEVKAMLDDADVFLLPSVTGADGDMEGIPVALMEAMAVGIPVVST
                     LHSGIPELVEADKSGWLVPENDARALAQRLAAFSQLDTDELAPVVKRAREKVEHDFNQ
                     QVINRELASLLQAL"
     gene            2642..4036
                     /gene="wcaM"
                     /locus_tag="ACHY1N_004709"
     CDS             2642..4036
                     /gene="wcaM"
                     /locus_tag="ACHY1N_004709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein WcaM"
                     /protein_id="HFS4046877.1"
                     /translation="MPFKKLSRRTFLTASSALAFLHTPFARALPARPSVNINDYNPHD
                     WIASFKQAFSEGQTVVVPAGLVCDNINIGIFIPAGKTLHILGSLRGNGKGRFVLQDGS
                     QVTGEEGGSMHNITLDVRGSDCTIKGLTMTGFGPVTQIYIGGKNKRVMRNLTIDNLTV
                     SHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISDHIIERINCT
                     NGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIK
                     ARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYLSIPQNF
                     RVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLFMRNIKV
                     MQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDRVNHHIV
                     NVEKINFRLPERRE"
     gene            4211..5104
                     /gene="galF"
                     /locus_tag="ACHY1N_004710"
     CDS             4211..5104
                     /gene="galF"
                     /locus_tag="ACHY1N_004710"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalF"
                     /protein_id="HFS4046878.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLELRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     gene            5476..6552
                     /gene="rfbB"
                     /locus_tag="ACHY1N_004711"
     CDS             5476..6552
                     /gene="rfbB"
                     /locus_tag="ACHY1N_004711"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFS4046879.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSKRYVFEHADICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDSDKKNSFRFHHISTDEVYGDLPHPDEVNNTEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKIGRELGWKPQETFESGIRKTINWY
                     LNNNDWCRRVQDGSYQRERLGVIR"
     gene            6549..7421
                     /gene="rfbA"
                     /locus_tag="ACHY1N_004712"
     CDS             6549..7421
                     /gene="rfbA"
                     /locus_tag="ACHY1N_004712"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014728539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFS4046880.1"
                     /translation="MKGIILAGGSGTRLYPITMGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIQDILIITTPEDQQGFMRLLGDGSQFGINLTYAIQPSPDGLAQAFIIGENFIGNDTV
                     CLMLGDNIFFGQGFTPKLRDAAERTSGATVFGYQVMDPERFGVVEFDRNFKALSIEEK
                     PANPKSNWAVTGLYFYDNNVIDIAKCIKPSKRGELEITAVNEVYLRNNNLTVELLGRG
                     FAWLDTGTHDSLIEAGSFVETVQKRQGMMVACPEEIAWRNGWLNHDELQAKGEFLKKN
                     HYGQYLLRLIKSHE"
     gene            7414..7821
                     /locus_tag="ACHY1N_004713"
     CDS             7414..7821
                     /locus_tag="ACHY1N_004713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FdtA/QdtA family cupin domain-containing
                     protein"
                     /protein_id="HFS4046881.1"
                     /translation="MNNNVKLIHFDKKGDNRGFLVVVEQNKDIPIEIKRVYYMFDTGS
                     DVRRGYHAHKKLTQIAIPVKGSCKFLLDDGKSVEHVTLDSPSVGLIIEPMIWHEMYDY
                     SSDCVLMVLADDFYDESDYIRNYADFIREITNA"
BASE COUNT         2183 a         1765 c         1944 g         2013 t
ORIGIN      
        1 cgccttatcc ggcctacggt tctgtgctcg ggtcttgtag gcctgataag acgcgccagc
       61 gtcgcatcag gcaaaaaacg gcaacgaaca caacaaacac agcctcacct ggcatcaaat
      121 ttatgaggaa aaaatgaaat tacttattct gggcaaccac acttgcggca atcgtggcga
      181 cagcgccatc ctgcgcggct tacttgatgc catcaacatc ctcaatccac acgccgaagt
      241 ggatgtgatg agccgctatc cggtcagttc ttcctggctg ctcaaccgcc cggtaatggg
      301 cgatccgctg ttcctgcaaa tgaaacaaca caacagcgcg gcgggcgttg tcgggcgcgt
      361 taaaaaagtc ctccgtcgcc gctatcagca ccaggtattg ctctcacgcg tcaccgacac
      421 tggcaagctg cgcaatatcg ccatcgccca gggattcacc gacttcgtgc gcctgctctc
      481 aggttacgac gccattattc aggtcggcgg atcgtttttt gtcgatctct acggcgtgcc
      541 gcagtttgaa catgcgcttt gcacatttat ggcgaaaaag ccgctgttta tgattggtca
      601 cagcgtcggt cccttccagg atgagcaatt taaccaactg gcgaactacg tttttggtca
      661 ctgtaacgcg ctgatcctgc gcgaatcggt cagtctcgaa ctgatgaaac gcagcaatat
      721 caccactgca aaagtggaac atggcgtcga taccgcgtgg ctggtcgatc accacaccga
      781 agatttcacc gccagctatg ccgtccaaca ctggctggac gttgccgcac aacagaaaac
      841 ggtggcaatt accctgcgcg aactggcacc gttcgacaaa cgcctcggca ccactcagca
      901 agcgtatgaa aaagcctttg ccggggtggt caatcgcatt ctcgacgaag ggtatcaggt
      961 gattgcgctc tccacctgta cgggcatcga cagctataac aaagacgacc gcatggtggc
     1021 gctcaacctg cgccagcaca tcagcgatcc tgcccgttat cacgtagtga tggatgaact
     1081 caacgatctg gaaatgggca aaattctcgg tgcctgtgaa ctcaccgtcg gtacgcgcct
     1141 gcactctgcc attatctcga tgaatttctc cactccggca attgccatca actacgaaca
     1201 taaatccgcc gggattatgc agcaactggg actaccggag atggcaattg atatccgtca
     1261 tttattagac ggcagcctgc aagcgatggt tgcggatacc ttaggccagc ttccggcgct
     1321 gaacgcgcga cataacgaag ctgtcagtcg tgagcgtcat acaggaatgc agatggtgca
     1381 gtctgtgctt gagcgcatcg gggaggtgaa atgaaggtcg gcttcttctt attgaaattt
     1441 ccgctgtcgt cggaaacctt cgtcctcaat caaattaccg cgtttattga tatgggcttt
     1501 gaggtggaga ttgtcgcgct gcaaaaaggc gacacacaaa acacccacgc ggcatggacg
     1561 aaatacaacc ttgccgccag aacccgctgg ttacaggacg aacctacggg caaagttgcg
     1621 aaactgcgcc accgcgccag ccagacctta cgcggcattc atcgtaaaaa tacctggcag
     1681 gcgctcaacc tcaaacgcta tggtgctgag tcgcgaaacc tgattttgtc tgccatttgc
     1741 ggcctggtcg caacaccgtt tcatgccgat gtctttatcg ctcattttgg cccggcgggg
     1801 gtaaccgcag caaaactccg cgaactgggt gtcattcgcg gcaaaattgc cactattttc
     1861 cacggcattg atatttccag tcgggaagtg ctcaaccatt acactcccga atatcaacaa
     1921 ctgtttcgac gtggcgacct gatgctaccg ataagcgatc tgtgggccgg aaggctgcaa
     1981 aaaatgggct gcccgaggga aaaaatcgcc gtatcgcgca tgggtgtaga tatgacgcgc
     2041 tttagcccgc gtcccgtgaa agcgcccgca acaccgctgg aaatcatctc cgtcgcacgc
     2101 ttaaccgaaa aaaaaggcct gcatgtggcg atcgaagcct gccgtcagtt gaaagagcag
     2161 ggcatggcat ttcgctatcg catcctcggc attggcccgt gggaacgacg cctgcgtacc
     2221 ctcatcgaac aatatcaact ggaagatgtg gtagagatgc cgggctttaa accgagccac
     2281 gaagtgaaag cgatgctcga cgacgcggat gtcttcctgt tgccatcggt aacgggcgcg
     2341 gatggcgata tggaaggcat tccggtagcg ctgatggaag cgatggcggt cggcattccg
     2401 gtggtttcta ctctgcatag cggaataccg gaattggtgg aggccgataa atccggctgg
     2461 ctggtgcctg agaacgatgc tcgcgcactg gcgcaacgac tggcggcgtt tagccaactg
     2521 gacaccgacg aactggctcc ggtcgtcaaa cgtgcgcgcg aaaaagtcga acacgatttt
     2581 aaccagcagg tgattaaccg agaactcgcc agcttgctgc aggctttata gaggagaacg
     2641 tatgccattt aaaaaactct cccgacgcac cttcctgacg gcaagctcgg cgcttgcctt
     2701 cctccatacc cctttcgctc gcgcacttcc tgctcgacca agcgttaata tcaacgatta
     2761 caatccgcac gactggatcg cctcatttaa acaagctttt agtgaagggc aaacggtcgt
     2821 cgtgcctgcc ggattggttt gtgacaatat caacatcggc atcttcattc ctgcaggtaa
     2881 aacgttacac atccttggaa gcctacgcgg caacggcaaa gggcgatttg ttttacagga
     2941 cggcagccag gtgacagggg aggagggcgg tagtatgcat aacatcaccc tggatgtgcg
     3001 tggttctgac tgcaccatca aagggctgac gatgaccggc tttggcccgg tgacgcagat
     3061 ctatatcggc ggcaaaaaca aacgggtcat gcgtaacttg accatcgata acctcactgt
     3121 cagccacgct aattacgcca tcttacgcca gggatttcat aaccagatta tcggtgccaa
     3181 catcaccaac tgtaagttca gcgacttaca aggcgacgcc attgaatgga acgtggcaat
     3241 taacgacagt gatattttga tctccgacca catcatcgag cgcatcaact gtactaacgg
     3301 caaaatcaac tggggcattg gcataggtct tgcgggaagc acttatgata ataattaccc
     3361 ggaagaccag gcagtgaaaa actttgtcgt ggcgaatatc acgggatcgg attgtcggca
     3421 gttgatccat gttgaaaatg gtaaacattt tgttatccgt aatatcaaag cccgcaatat
     3481 cacgccggat ttcagtaaga aagcaggtat tgataacgcg acagtcgcta tttacggttg
     3541 tgataatttc gtgattgata atattgaaat gattaatagt gccggaatgt taatcggcta
     3601 tggggtaatt aaaggcaaat atctctcgat accacaaaat ttccgagtga ataatattca
     3661 actggataat acccaccttg cttacaaatt gcgcggtatc caaatctctg ccgggaatgc
     3721 cgtctccttt gtggcactga ctaacattga gatgaagcgt gcgtctctgg agttacacaa
     3781 caaaccgcaa catcttttta tgcgtaatat caaagtgatg caggaatcct ctgttggacc
     3841 cgcattgagc atgaactttg acatgcgcaa agacgttcgc ggcgtcttta tggcgaaaaa
     3901 agaaaccctg ctatctcttg caaatgttca tgcggtgaat gagaaaggac aaagctccgt
     3961 cgatatcgat agggttaatc accatattgt taatgtggaa aagattaact ttagattgcc
     4021 ggaacggaga gagtagattt gcgaccattc ctggaaaaat ggagccatac ttaggaacaa
     4081 tgctactgca atccacaacg aagcggcgta acatcacaag taattcagta atcaattcag
     4141 ggtaattgat gctggcgaaa aaaatcgaac aagctataat tcagcaacca ttttacaggt
     4201 ggatgaaata atgacgaatt taaaagcagt tattcctgta gcgggtcttg ggatgcatat
     4261 gttgcctgcc actaaggcga ttcccaaaga gatgctaccg atcgtcgaca agccaatgat
     4321 tcagtacatt gttgacgaga ttgtggctgc agggatcaaa gaaatcctcc tggtaactca
     4381 cgcgtccaag aacgcggtcg aaaaccactt cgacacctct tatgaattag aatctcttct
     4441 tgaactgcgc gtgaagcgtc agctgctggc ggaagtgcag tccatctgtc cgccgggcgt
     4501 gaccattatg aacgtgcgtc agggcgaacc tttaggttta ggtcactcca ttttgtgtgc
     4561 gcggcctgcc attggtgaca atccatttgt cgtggtgctg ccagacgttg tgatcgacga
     4621 cgccagcgcc gacccgctgc gctacaacct tgctgccatg attgcacgat tcaacgaaac
     4681 gggtcgtagc caggtgctgg caaaacgtat gccgggtgac ctctctgaat actcggtcat
     4741 ccagaccaaa gaaccactgg accgtgaagg taaagtcagc cgcattgttg aatttatcga
     4801 aaagccggat cagccgcaga cgttggactc agacatcatg gccgttggtc gctatgtgct
     4861 ttctgccgat atttggccgg aacttgaacg cactcagcct ggtgcatggg ggcgtattca
     4921 gctgactgat gccatcgctg aactggcgaa aaaacagtcc gttgatgcca tgctgatgac
     4981 aggtgacagc tacgactgcg gtaaaaaaat gggctatatg caggcgttcg tgaagtatgg
     5041 gctgcgcaac ctgaaagaag gggcgaagtt ccgtaaaggg attgagaagc tgttaagcga
     5101 ataatgaaaa tctgaccgaa tgtaacggtt gataagaaaa ttattacggc agtgaagatt
     5161 cgtggcgaaa gtaatttgtt gcgaattttc ctgccgttgt tttatataaa caatcagaat
     5221 aacaacgagt tagcaatagg attttagtca aagttttcca ggattttcct tgtttccaga
     5281 gcggattggt aagacaatta gcgtttgaat ttttcgggtt tagcgcgagt gggtaacgct
     5341 cgtcacatcg tggacatgta tgcagtgctc tggtagctgt aaagccaggg gcggtagcgt
     5401 gcattaatac ctctattaat caaactgaga gccgcttatt tcacagcatg ctctgaagta
     5461 atatggaata ataaagtgaa gatacttgtt actggtggcg caggatttat tggttctgct
     5521 gtagttcgtc acattataaa taatacgcag gatagtgttg ttaatgtcga taaattaacg
     5581 tacgccggaa acctggaatc acttgcagat gtttctgact ctaaacgcta tgtttttgaa
     5641 catgcggata tttgcgatgc tgctgcaatg gcgcggattt ttgctcagca tcagccggat
     5701 gcagtgatgc acctggctgc tgaaagccat gtggatcgtt caattacagg ccctgcggca
     5761 tttattgaaa ccaatattgt tggtacttat gtccttttgg aagccgctcg caattactgg
     5821 tctgctcttg atagcgacaa gaaaaatagc ttccgttttc atcatatttc tactgacgaa
     5881 gtatatggtg atttgcctca tcctgacgag gtaaataata cagaagaatt acccttattt
     5941 actgagacaa cagcttacgc gccaagcagc ccttattccg catcaaaagc atctagcgat
     6001 catttagtcc gtgcgtggaa acgtacctat ggtttaccga ccattgtgac taactgttcg
     6061 aataactacg gtccttatca ctttccggaa aaattgattc cactagtaat tcttaatgct
     6121 ctggaaggta aggcattacc tatttatggt aaaggggatc aaattcgcga ctggctgtat
     6181 gttgaagatc atgcacgtgc gttatatacc gtcgtaaccg aaggtaaagc gggtgaaact
     6241 tataacattg gtggacacaa cgaaaagaaa aacatcgatg tagtgctcac tatttgtgat
     6301 ttgttggatg agattgtacc gaaagagaaa tcttaccgcg agcaaattac ttatgttgcc
     6361 gatcgtccgg gacacgatcg ccgttatgcc attgatgctg agaagattgg tcgcgaattg
     6421 ggatggaaac cacaggaaac gtttgagagc gggattcgta aaacaattaa ctggtatttg
     6481 aataataatg attggtgccg gcgagttcaa gatggctctt atcaacgtga gcgtttgggg
     6541 gtaattagat gaaaggaatt attttagctg gtggttctgg aacaaggctt tatccaatta
     6601 caatgggagt ttcaaagcag ctattaccca tttatgataa accgatgatt tattatcctt
     6661 tgtcggtgct gatgttggca ggtatacaag atattcttat tattacaacg ccagaagatc
     6721 agcaagggtt catgagatta cttggggatg gaagccaatt tggtattaat ctgacatatg
     6781 caattcaacc tagtccagat ggtttagccc aagcatttat tattggtgaa aactttattg
     6841 gaaatgacac agtatgcctt atgcttggag ataacatttt ttttggacaa ggttttacac
     6901 ccaaactccg ggatgcagca gaaagaacat caggtgccac agtctttgga tatcaagtaa
     6961 tggatcctga gagatttgga gtagtggagt ttgataggaa ttttaaagct ttaagtattg
     7021 aagaaaaacc tgccaatcca aaatcaaatt gggctgtcac aggattatat ttttatgaca
     7081 ataacgttat cgatattgca aagtgtatta aaccttctaa acgtggtgaa ttagaaatta
     7141 cggcagttaa tgaagtttat ctcagaaata ataatttaac tgttgaatta ctaggacgtg
     7201 gttttgcatg gctggataca ggaacccatg acagcttgat tgaagctggg agttttgtag
     7261 agacagttca aaaaaggcaa gggatgatgg ttgcttgtcc ggaggagatt gcatggcgaa
     7321 atggctggtt aaaccatgat gaattacagg caaaaggtga atttttgaaa aaaaatcact
     7381 atggacagta tttactaagg ttaattaaat cgcatgaata ataacgtaaa acttatacac
     7441 tttgataaga aaggtgacaa ccgaggcttt cttgttgttg ttgagcaaaa taaagatatc
     7501 ccaattgaaa ttaaacgagt ttactacatg tttgatactg gttctgatgt aagacgggga
     7561 tatcacgcac ataaaaaact tacacaaata gcaatccctg ttaagggatc ttgcaagttt
     7621 ttgcttgatg acggtaaatc ggtggaacat gttacattag attcaccgtc agtgggatta
     7681 attatagaac caatgatttg gcatgaaatg tacgattatt catcagattg tgttttaatg
     7741 gtgctggcag atgactttta tgatgaaagt gattacattc gtaattatgc tgatttcatc
     7801 agggagataa ctaatgcgta atttgtcgct ctttacaaaa aatacaaaat taattccagt
     7861 tgaaataaat gatgcggaat ttatttattc actgcggata gattc
//
LOCUS       DAZUDJ010000129         7905 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.131, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000129 DAZUDJ010000000
VERSION     DAZUDJ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7905
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.131"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..462
                     /locus_tag="ACHY1N_004714"
     CDS             <1..462
                     /locus_tag="ACHY1N_004714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HFS4046882.1"
                     /translation="AINFSRPAGQVIAQYYEFLRLGREGYTKVQNASYQVAAYLADEI
                     AKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRLRGWQVPAFTLGGEA
                     TDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT"
     gene            832..1656
                     /gene="gadX"
                     /locus_tag="ACHY1N_004715"
     CDS             832..1656
                     /gene="gadX"
                     /locus_tag="ACHY1N_004715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadX"
                     /protein_id="HFS4046883.1"
                     /translation="MQSLHGNCLIAYARHKYILTMVNGEYRYFNGGDLVFADASQIRV
                     DKCVENFVLVSRDTLSLFLPMLKEEALNLHAHKKISSLLVHHCSRDIPVFQEVAQLSQ
                     NKNLRYAEMLRKRALIFALLSVFLEDEHFIPLLLNVLQPNMRTRVCTVINNNIAHEWT
                     LARIASELLMSPSLLKKKLREEETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGY
                     HSVSYFIYVFRNYYGMTPTEYQERSAQGLPNRDSAASIVAQGNFYGTDRSAEGIRL"
     gene            2024..2752
                     /gene="gadW"
                     /locus_tag="ACHY1N_004716"
     CDS             2024..2752
                     /gene="gadW"
                     /locus_tag="ACHY1N_004716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadW"
                     /protein_id="HFS4046884.1"
                     /translation="MTHVCSVILIRRSFDIYHEQHKISLHNESIVLLEKNLADDFAFC
                     SPDTRRLDIDELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNESG
                     VNSPILSNMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAE
                     RMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYF
                     INTFRQYYGVTPHQFAQHSPGTFS"
     gene            complement(3115..6228)
                     /gene="mdtF"
                     /locus_tag="ACHY1N_004717"
     CDS             complement(3115..6228)
                     /gene="mdtF"
                     /locus_tag="ACHY1N_004717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump RND permease MdtF"
                     /protein_id="HFS4046885.1"
                     /translation="MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTIT
                     VSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDI
                     AQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS
                     NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQ
                     LGGMPQAADQQLNASIIVQTRLQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYS
                     TVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIE
                     ISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLS
                     AVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHKPN
                     ALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLCTPTSFLPEED
                     QGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKDNVQSVFTVGGFGFSGQGQNNGL
                     AFISLKPWSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMEL
                     LDNGNLGHEKLTQARNELLSLAAQSPDQVTGVRPNGLEDTPMFKVNVNAAKAEAMGVA
                     LSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP
                     LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYS
                     WTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLAT
                     DLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPIEAIIEAARMRLRP
                     ILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHL
                     FARFKKA"
     gene            complement(6253..7362)
                     /gene="mdtE"
                     /locus_tag="ACHY1N_004718"
     CDS             complement(6253..7362)
                     /gene="mdtE"
                     /locus_tag="ACHY1N_004718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtE"
                     /protein_id="HFS4046886.1"
                     /translation="MLTACDDKSAENAAAMTPEVGVVTLSPGSVNVLSELPGRTVPYE
                     VAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELNSAKGSLAKALSTASNA
                     RITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAVEQATINLQYANVTSPI
                     TGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQDFLRMKEEVASGQIKQV
                     QGSTPVQLNLENGKRYSQTGTLKFSDPTVDETTGSVTLRAIFPNPNGDLLPGMYVTAL
                     VDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIEASKAIGDQWVVTSGLQ
                     AGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ"
     gene            7470..7748
                     /locus_tag="ACHY1N_004719"
     CDS             7470..7748
                     /locus_tag="ACHY1N_004719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046887.1"
                     /translation="MRDLQTSGIVGLSASKVGYRHSDRHGEVNDKKNVAVLPTVPASI
                     RATKGSTGGYTYQGNKVVLASPLVITGGNEISICIPRHASHQFQLLMS"
     gene            complement(7749..>7905)
                     /gene="gadE"
                     /locus_tag="ACHY1N_004720"
     CDS             complement(7749..>7905)
                     /gene="gadE"
                     /locus_tag="ACHY1N_004720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadE"
                     /protein_id="HFS4046888.1"
                     /translation="QLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKLRRMSDIVT
                     LGITSYF"
BASE COUNT         2008 a         1894 c         1925 g         2078 t
ORIGIN      
        1 gccatcaact tctcccgccc ggcgggtcag gtaattgcac agtactatga attcctgcgc
       61 ctcggtcgtg aaggctatac caaagtacag aacgcctctt accaggttgc cgcttatctg
      121 gcggatgaaa tcgccaaact ggggccgtat gagttcatct gtacgggtcg cccggacgaa
      181 ggcatcccgg cggtttgctt caaactgaaa gatggtgaag atccgggata caccctgtac
      241 gacctctctg aacgtctgcg tctgcgcggc tggcaggttc cggccttcac tctcggcggt
      301 gaagccaccg acatcgtggt gatgcgcatt atgtgtcgtc gcggcttcga aatggacttt
      361 gctgaactgt tgctggaaga ctacaaagcc tccctgaaat atctcagcga tcacccgaaa
      421 ctgcagggta ttgcccagca gaacagcttt aaacacacct gataacataa cgttgtaaaa
      481 accgaatgcc cagcctttaa aaaaacagct gggcattcgg ttgcttatta atcgcaataa
      541 tatattggct gtctattcat cgtgttgata agatatatgt tatatgaatg tttattaaat
      601 gtagcgattg cctttaatgt cacgaaaagg gattatttgc ttgctattaa tttcactgcg
      661 ttcttaaaca cgtttttgta ttataaatcc agtcatcctg cccgtagaac atcacacatt
      721 atcatcctgt tctcccgctt cgtttaaatt tatttatcaa tcaatttgac ttaagagggc
      781 ggcgtgctac attaattaac agtaatatgt ttatgtaata ttaagtcaac tatgcaatca
      841 ttacatggga attgtctaat tgcgtacgca agacataaat atattctcac catggttaat
      901 ggtgaatatc gctattttaa tggcggtgac ctggtttttg cggatgcaag ccaaattcga
      961 gtagataagt gtgttgaaaa ttttgtatta gtatcaaggg atacgctttc attatttctg
     1021 ccgatgctca aggaggaggc attaaatctt catgcacata aaaaaatttc ttcattactc
     1081 gttcatcact gtagcagaga tattcctgtt tttcaggaag ttgcgcaact atcgcagaat
     1141 aagaatcttc gctatgcaga aatgctacgt aaaagagcat taatctttgc gttgttatct
     1201 gtttttcttg aggatgagca ctttataccg ctgcttttga acgttttgca accgaacatg
     1261 cgaacacgag tttgtacggt tatcaataat aatatcgccc atgagtggac actagcccga
     1321 atcgccagcg agctgttgat gagtccaagc ctgttaaaga aaaaattgcg cgaagaagag
     1381 acatcatatt cacagttgct tactgagtgt agaatgcaac gtgctttgca acttattgtt
     1441 atacatggct tttcaattaa gcgagtcgca gtgtcctgtg gatatcacag cgtgtcgtat
     1501 ttcatttacg tctttcgaaa ttattatggg atgacgccca cagagtatca ggagcgatcg
     1561 gcgcagggat tgccgaaccg tgactcggcg gcaagtattg ttgcgcaagg aaatttttac
     1621 ggcactgacc gttctgcgga aggaataaga ttatagaatt ttactcagac ataaaaaaaa
     1681 cccggcatag gggaccggga agaggatagt ctgccgtctc cagactaata aaccgttata
     1741 acactccctg ttggcacggg aaactttgtg ctctcagtaa gttaaatata acttttactg
     1801 gaaataagat cagccatttt tttataaaca taagctatac gcagtgcgaa aatatattcg
     1861 tgctgcattt acttattatc aattaactgt tatgcaaaac tactttgtgg ataaattttg
     1921 gtcctaccaa atctggcagt tttttcgcta agaaacagtc tggcaacatt tcattagtat
     1981 actgaaattg aaataatcgc agtatgaaat ataagggata atcatgactc atgtctgctc
     2041 ggtgatcctc attcgtcgtt cattcgatat ttatcatgaa cagcataaaa tatcgctgca
     2101 taacgagagt atcgtgctgc tggagaaaaa tttggcagac gattttgcgt tttgttcacc
     2161 ggatacgcga cgactggata tcgatgagct gacagtttgc cattacttac aaaatattcg
     2221 tcagctacca cgcaatttag ggttacatag caaagaccgt ctattaatta accagtcacc
     2281 ccccatgccg ctggtgacgg cgatttttga tagcttcaat gaatccgggg taaattcacc
     2341 gatactgagc aatatgctct acctttcctg tttatcgatg ttttctcata agaaagaact
     2401 gatcccctta cttttcaata gcatcagcac tgtttcagga aaagttgaac gccttattag
     2461 ctttgatatc gccaaacgtt ggtatctgcg cgatatcgcg gaaagaatgt ataccagcga
     2521 gagtctcatc aaaaaaaagt tgcaggatga aaatacctgt ttcagtaaaa tattactcgc
     2581 ttccaggatg tcgatggcca gacgattact cgagttacgt caaattcctc tgcatactat
     2641 tgcagaaaaa tgtggctata gcagtacgtc gtactttata aacacatttc gacaatatta
     2701 tggtgtaacg ccacatcagt ttgcgcaaca ttcgccaggt accttttcct gacatatttt
     2761 gcatttgaat attggtcagg atctcacacc tgcttcatgt gaaactcttc cctgatgatt
     2821 tctgccgggc taccggctag ttctctttcg cagtttgcca ggcggtatag gtattttcag
     2881 gaggaaaaga ctcggcatgt ttgggattat taagctgaca attcatacga ttacgggaat
     2941 gtgggtcagt attgtgctgt tcaaattgat gacgaatggc tggagtggtt tctactttca
     3001 gtgctgtgta ctaagcctgg tattcctgac ggttagctgg ttgttgagtg gtgaatggtt
     3061 agcaggaaag agtaaggctg aaccttcacg ttcaacctta ctctcattta cacgttacgc
     3121 ttttttaaag cgggcaaaga gatgttccac tacaacgaaa aagaccggaa cgaagtaaat
     3181 tgccagcact gttgcggcaa acatcccgcc catcacgccg gtacctaccg cgttttgcgc
     3241 gccagaaccg gcaccatgac tgataaccag cggcagcacg ccgagaataa aggccagaga
     3301 ggtcatcagg attgggcgta aacgcatccg cgccgcttcg atgattgcct ctatcggcgt
     3361 tttcccttct ttctgcatca tctcaacggc aaattcgaca atcaggatgg cgttcttggc
     3421 ggaaagcccg atggtggtca gcaaaccaac ctggaagtag acgtcattac ttaagccgcg
     3481 cagatcggtg gccagtaatg cgccaacgac gcctaacgga acaaccaaca tcaccgagaa
     3541 cggaattgac cagctctcat agagtgcggc gagggcgagg aacaccacga ccagtgaaat
     3601 ggcatacagt gcaggagcct ggtttgagga taacgcttcc tgatacgaca gtccggtcca
     3661 tgagtagccg acgcctgccg gaagtttagc gaccaggtct gccataaatt tcatagcgtc
     3721 accggtactt ttcccggccg ccgcttcacc taaaatctcc attgacggga tgccgttgta
     3781 gcgttccaat cgcggtgaac cataggtcca ttcggtagac gagtaggcag aaagcggtgc
     3841 catcgtgcca gaggcgttgc gtacatacca ttggttgatg ttatccggca acatacggaa
     3901 cggcgtgcct gcctggacat acactttttt cacccgcccc tggttgagga agtcgttcac
     3961 gtagctgctg ccgaaggcgg tggaaattgt ctggttgata tcagacagcg ccacacccat
     4021 tgcctcagct ttcgcggcgt tgacgttcac tttgaacatc ggcgtatctt ccaggccgtt
     4081 cgggcgtacc ccggtgacct ggtcaggcga ttgcgctgcc agtgataaca gctcgtttcg
     4141 tgcctgggtt agtttttcgt gccccaggtt accgttgtcc agcagttcca tatcaaaacc
     4201 tgacgcggta cccagttcag ccaccgcggg taagttgaac gggaagacga cggctttatt
     4261 gatactgctt aacgcaatca ttgcccgctg aatgatcgcg gtaaccgagt tttcctcacc
     4321 gacacgttca gaccacggct tgagactgat aaacgccagg ccgttgtttt gcccctggcc
     4381 gctgaagcca aagccgccaa cggtaaacac cgactgaaca ttatctttct cttttgtaag
     4441 ataataatcc gtcacctgtt gcagcacttt cgtggtgtta accatggtgg caccggaagg
     4501 taactgcgcg gtggtcataa ataccccctg atcctcttct ggtaagaaag aggtcggtgt
     4561 acacaggaac agcaccgcca tcccggcgca aatcagcagg tagaccacca tgtagcgacc
     4621 ggtacaacgc aacagcgagc gggtgctatc ggtatagtgc tgagttgatt tttcaaacag
     4681 cgtgttgaag cgtgcgaaca gggcgttagg tttgtgaccg ccttccggcg cggctttcag
     4741 aatggtggcg cacagggcag gggtcaggct cattgccaca aatactgaaa gcagcatgga
     4801 ggagatcagc gtgatggaga actggcggta gatctccccg gttgcgccgc tcataaaggc
     4861 catcggcata aacactgcgg aaagaacaac agcaataccg accagcgcac gttggatctg
     4921 ccccatcgat ttatgcgtcg cttccttcgg tggtagctta tcttccgcaa tgacacgctc
     4981 gacgttctcc accaccacga tggcgtcatc caccagtagc cctatcgcca gcaccatccc
     5041 gaacatagtt aacgtgttga tggtgaaacc gaccgccgac aagatcgcaa acgtcccgag
     5101 aataaccacc ggtacggcaa tcgtcgggat gattgtggca cggaaattct gcaaaaacag
     5161 atacatgacc aggaagacga ggatgatagc ctcaaccagt gttttaaaaa cttcctgaat
     5221 agaaatttcg ataaacggcg tggtgtcgta aggataaacc gtcttcagac ttgcggggaa
     5281 ataggctgat aagcggttca gctcctcttt gactgcccgc gaggtatcca gggcgtttgc
     5341 tccggtagcc agtttgatgg cgatcccggc agcaggtttg ccgttatagc gcgccacggt
     5401 ggaataatct tccgctccaa gttcgacgcg ggcgacatca cgcagcagca cttgcgaacc
     5461 atcttgctga actttcaaca ggattttgcc aaattcttcc ggcgtttgca gacgcgtctg
     5521 cacaatgatc gaggcgttta gttgctggtc tgccgcctgt ggcatgccac ccagttgacc
     5581 accggaaatc tggttgtttt gcaccttaat ctgggaaata acatcggaag gtaccagatt
     5641 gtatttattg agtttttgcg ggtccagcca gatacgcatg gcgtactcgg aaccaaagag
     5701 ctgtacgcta ccaacgcccg cggtacggct tagcgggtct ttgatattag acgctacata
     5761 gtccgcgata tcgtactggt tgaggctgcc gttatcagaa ataaacgccg ctaccatcag
     5821 aatattactg ctcgacttat caacgctaat cccctgctgc tgcaccgctt caggtaatga
     5881 aggcatagcg agttgcagtt tattttgcac ctgaacctgt gcgatatcag gagatgtccc
     5941 agtctcgaag gtcagagtga tagaggcatt acccgccgca tcactggttg aagacatgta
     6001 catcaggcca tcaagcccat tcatattttg ctcaatcacc tgagtgaccg agtcttctac
     6061 cgtttgcgca tcggcacctg gataggtagc gctgacggta atggtcggtg gcgcaatctg
     6121 cggatactgc gcaaccggta agttcatgat cgccagacca cctgcaagca tcataataat
     6181 ggcaagtacc caggcaaaaa ccgggcgatc aataaaatag ttagccatga aagtcccctt
     6241 aagcctgcaa cgttattgtt tcgattcggt gctggcgttt tcctggctgg aggaaattgc
     6301 tcgtgctttg atacccggac gaatgcgttg caaaccggaa acgatcaccc gatcgccagc
     6361 ctgcaagcca gaggtgacaa cccactggtc gccgatggct ttgctggctt caatttcgcg
     6421 tagctgcaca acatcgtctt tatccagaat gagcgccgtt gctttaccct gggcgttgtg
     6481 ggtgacgcct tcctgcggca ccagtaatac attctggcgg ctaccttcat ccactaatgc
     6541 cgtgacgtac atgccaggca gcaagtcacc atttgggttg gggaaaatcg cccgtaacgt
     6601 cacggagccc gtggtttcat ccaccgtcgg gtcggagaat ttcagcgtgc cggtctggct
     6661 gtagcgttta ccattttcca gattgagctg tactggcgta ctgccctgaa cctgtttgat
     6721 ttgcccactg gcgacctctt ctttcatgcg taagaaatcc tgcaccgact gcgtgagatc
     6781 gacataaatc gggtccagac gttgtacggt aaccagcgaa tctgcctgat tagcggtaac
     6841 gagtgcgccg acggtcaccg acgatttccc gctgacgccc gtaatcggcg aggtgacatt
     6901 cgcgtattgc agattgatcg tcgcctgttc aacagccgct ttggcgacgg tgacattggc
     6961 ttctgcttca ttcaactggg tgcgcgcggt gtcgtaatcc tgacggctaa cgtagttggt
     7021 cttcagcaac gatgcctggc ggttaaaggt gatgcgggca ttgctggcgg tagagagcgc
     7081 tttcgccagc gagcctttgg cggagtttag ctcggcctgt aaaggtgcag gatcaatctg
     7141 atacagcgaa tcgccctggt tcactttatc gccttcgata aagttgcgtt taatgataat
     7201 accgcccacc tggggacgta tctcggcaac ttcataagga acggttctac cgggcaattc
     7261 gctcaacaca ttgaccgaac cgggggagag tgtgacgaca ccgacctcag gcgtcatggc
     7321 ggcggcgttt tccgccgatt tgtcatcgca ggcggtgagc atcgcgccgc agaaaaacaa
     7381 cggtattaac agctttcttc ttctgttcat tttagtccct gaaaattctt gagaaataac
     7441 ggttctttaa attgcgcgcg aggagagata tgagggattt acagaccagc ggcatagtgg
     7501 ggttgtcagc cagtaaggtg ggatacaggc acagtgatcg acatggtgag gtcaacgaca
     7561 aaaaaaatgt tgccgttctg ccaacagttc ctgccagcat tcgggcaacg aagggttcta
     7621 ctggtggata cacataccag gggaataaag tcgttttagc ctctccttta gtaatcaccg
     7681 ggggtaatga aatcagcatc tgcatccctc gtcatgccag ccatcaattt cagttgctta
     7741 tgtcctgact aaaaataaga tgtgataccc agggtgacga tgtcgctcat acgtcttagt
     7801 ttcagcttgt acataatgtt gaatttctga atctttaatg tttgttgcga aatattgagc
     7861 gtcgacgtga tattgctttc atttttattt ttcagaatca gttgc
//
LOCUS       DAZUDJ010000130         7822 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.132, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000130 DAZUDJ010000000
VERSION     DAZUDJ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7822
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.132"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..155)
                     /locus_tag="ACHY1N_004721"
     CDS             complement(<1..155)
                     /locus_tag="ACHY1N_004721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046889.1"
                     /translation="MLQSSADKACNVLVKKVRYLKDVRKITKMMNGKLIYSWLKWPCG
                     EFFSLNY"
     gene            233..1327
                     /gene="ddlA"
                     /locus_tag="ACHY1N_004722"
     CDS             233..1327
                     /gene="ddlA"
                     /locus_tag="ACHY1N_004722"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFS4046890.1"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNDNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     gene            complement(1351..1563)
                     /gene="yaiZ"
                     /locus_tag="ACHY1N_004723"
     CDS             complement(1351..1563)
                     /gene="yaiZ"
                     /locus_tag="ACHY1N_004723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414914.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 domain-containing protein"
                     /protein_id="HFS4046891.1"
                     /translation="MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVG
                     LVTWVISFWLAGLIIRRRDEETENAQ"
     gene            1823..2131
                     /gene="yaiY"
                     /locus_tag="ACHY1N_004724"
     CDS             1823..2131
                     /gene="yaiY"
                     /locus_tag="ACHY1N_004724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiY family protein"
                     /protein_id="HFS4046892.1"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     gene            complement(2190..3284)
                     /gene="yaiW"
                     /locus_tag="ACHY1N_004725"
     CDS             complement(2190..3284)
                     /gene="yaiW"
                     /locus_tag="ACHY1N_004725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HFS4046893.1"
                     /translation="MSRVNPLSSLSLLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLISMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTE
                     LATRKLAGKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEAKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     gene            complement(3297..4517)
                     /gene="sbmA"
                     /locus_tag="ACHY1N_004726"
     CDS             complement(3297..4517)
                     /gene="sbmA"
                     /locus_tag="ACHY1N_004726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706191.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904680 - peptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HFS4046894.1"
                     /translation="MFKSFFPKPGAFFLSAFVWALIAVIFWQAGGGEWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFAFFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSTHVPELPIIGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     gene            4869..6026
                     /gene="ampH"
                     /locus_tag="ACHY1N_004727"
     CDS             4869..6026
                     /gene="ampH"
                     /locus_tag="ACHY1N_004727"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase AmpH"
                     /protein_id="HFS4046895.1"
                     /translation="MKRSLLFSAVLCAASLTSVHAAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVVRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     gene            complement(6027..6650)
                     /gene="iprA"
                     /locus_tag="ACHY1N_004728"
     CDS             complement(6027..6650)
                     /gene="iprA"
                     /locus_tag="ACHY1N_004728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HFS4046896.1"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNNEDT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
     gene            complement(6738..>7822)
                     /gene="ehaB"
                     /locus_tag="ACHY1N_004729"
     CDS             complement(6738..>7822)
                     /gene="ehaB"
                     /locus_tag="ACHY1N_004729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="autotransporter adhesin EhaB"
                     /protein_id="HFS4046897.1"
                     /translation="RIDNATGAGAIADYKDKEIIYVNDVNTNATFSAANKADLGAYTY
                     QAEQRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGA
                     WVSYFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSG
                     QVDQDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFG
                     LKAGYDFKLGDAGYVTPYGSISGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYT
                     FTYSEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSA
                     YTDANYLGGGDVDQDWSANVGVKYTW"
BASE COUNT         1970 a         1991 c         1905 g         1956 t
ORIGIN      
        1 ttataattaa gagaaaaaaa ctcaccgcat ggccatttaa gccaggaata aattagcttc
       61 ccgttcatca tttttgtgat cttgcgcaca tctttgagat aacgcacttt cttcaccagt
      121 acgttgcacg ctttgtcagc agaagattgc aacaatcttt cagaaggccg cgaatccccc
      181 gttttgtcgt ggtaatgtat gcactttgtg ttagacggga taggttttta agatggaaaa
      241 actgcgggta ggaatcgttt ttggtggtaa atcagcggaa catgaagtgt ctctgcaatc
      301 ggcaaaaaac attgtcgatg ccattgataa aagtcgcttc gacgttgtgc tgctgggcat
      361 tgataaacaa gggcaatggc acgtcagcga tgccagcaat tatctgctaa atgcagacga
      421 tcctgcccat attgcgttgc gcccttcggc gaccagcctt gcgcaggtgc caggtaaaca
      481 tgagcatcag cttatcgacg cgcaaaacgg tcagccgttg ccgacggtgg atgtcatttt
      541 cccgattgtc cacggtacgc tgggcgaaga tggttccttg cagggaatgc tgcgggtcgc
      601 caatttaccg tttgtaggtt ctgatgttct ggcttcagca gcctgtatgg ataaagatgt
      661 caccaaacgt ctgctacgcg atgccgggct gaacattgcg ccatttatta ccctgacgcg
      721 cgctaatcgt cacaacatca gttttgccga agtggagtct aaactggggt taccactgtt
      781 tgtaaaaccg gctaatcagg gctcttctgt tggtgtcagc aaagtaacca gtgaagaaca
      841 gtacgcaatt gccgtcgatc tggcgttcga gttcgatcat aaagtgatcg ttgagcaagg
      901 gatcaaaggt cgtgagatcg aatgcgcagt tctgggcaac gacaatccgc aagccagcac
      961 ctgtggcgag atcgtactca ccagcgattt ctatgcctac gacaccaagt acattgacga
     1021 agatggcgcg aaagtggtag ttccggcagc cattgcacca gagatcaacg ataagatccg
     1081 ggcgattgcc gttcaggctt atcagacgtt gggatgcgca ggcatggcgc gtgtagacgt
     1141 gtttttaacc ccagagaacg aagtggtgat caacgagatc aacacactgc ctggcttcac
     1201 caacatcagt atgtatccga agctgtggca agccagcggt ctgggttaca ccgatctgat
     1261 cacacgtttg attgagctgg cgctggagcg tcacgctgcg gataacgcat tgaaaaccac
     1321 aatgtaatat tttaacgccc gataatattc ttattgggcg ttttcagttt cttcatcgcg
     1381 acgacgaata atcaaccccg ccagccagaa actaatcacc cacgtcacca gaccgacggc
     1441 ataggtctgc caaccttttg cttcaaatcc cagtaacccc accacgccat taagaatgaa
     1501 tataaggcca atggcgaacg catagtagtg ccagtcacgg cggattttta caggcagatt
     1561 catggcagct ccgttaacga aaaacaacat ccttgcatat tctgtaacaa ccgtctgtgg
     1621 tgtagacaac attttcgtaa ttgttaataa atttaactta aggttgccat tttgtgactc
     1681 acaacgaaga ttcacgcttc gggaatattc ccaacatcaa tttaccatga ttctgatatt
     1741 gacaatctaa atgacctgtc agacttgcca taagccgctg gtatcacacc agaagagaag
     1801 cagatgactt ccggaggttt ttatggctga tttcaccctg tcaaaatcgc tgtttagcgg
     1861 aaaatatcgc aatgcctctt caacgcctgg caacattgcc tatgcgttgt ttgtgctgtt
     1921 ttgcttttgg gctggggcgc aattgctgaa cctgttagtg catgcgcccg gcgtctatga
     1981 gcgtttaatg caggtccagg aaacaggtcg cccacgggtg gaaattggtt taggtgtcgg
     2041 caccattttc gggctgatcc cgtttttagt aggctgcctc atttttgcag tggtggcgct
     2101 atggctgcac tggcgacatc gccgccagta agatttacgt tgccagatac ggcctaaaac
     2161 gccttatctg gcatgacatt cctgtttgat cactgtttca tacaacgcgc ccgccgttcg
     2221 tctacgcgct tcgcaaacca ggccgtagtc aggttgcggg tgattttcgg gctttccagt
     2281 tgaatgccag gcaacatttc gcggggtagt gatttacccg ttttcgcttc ggcaagttga
     2341 taaactttct tgtacagcgc cgtctcctca aaagagaagc tgtcaccttt ctctaactga
     2401 cggcgaattt cgctgtcgct catccccagt tttcccgcca gtttgcgcgt tgccagttcg
     2461 gttttcccgg gttctttact gtcgtaacga attaaatcac cgtccagtgc cagcttcacg
     2521 ccgctggcct tactgactgc gttctgaaac gcggcattac ggctggcgta ccagccagcg
     2581 ttaaaatcag caaagcggta tatcggtgcg ctatagctgg cgggataatt cagtaaatgg
     2641 taagtaccaa accacaaccc gccgcggcga ctgaagactt cctgacgaac tgtaccgtcc
     2701 attttccacg gatacccttt ggtatgctgt tcggcaaaag caatgctgac ctgcatcggc
     2761 ccaccggtgc gcacaggatt aagcgaacca aacagcgtct gccccattgg taccatgctg
     2821 atcagatcgt caaaaatcgc gctcaattgc ttttctgtac gcaccgaatc taaccgttcg
     2881 ctataacttt tgccgtttgg cgatttgatt tttagcgcgg tatgaaccag aaaagcagga
     2941 atgtgcatcc gttcagcacg acggtcaatc tcttgccagg cgatcttgct taagcccgga
     3001 acggccggat ctgcctgata atttgactcc tgctgcgcca ccgccagcac cgagcagacg
     3061 ttttccagcg tcggtgccag cccctgactt tcaaaggtgg tggcgagatc tttcgcccag
     3121 gcatcgcggt ctttcacgct cgcaggcatc ttctgccgca cgacgctcgc cacatctatc
     3181 gctttttcgc cctttttcaa cggttgcgga gcctgactac tacaccccgc taaaaccaga
     3241 accgccaaca atgacagcga agatagagga ttgacgcgcg acattacttc tcctttttag
     3301 ctcaaggtat gggttacttc ctgaattttg tcaccatcca gttcatgttc aaagctgcgc
     3361 agacgtttgt agatagacat caactcaacc agtgtggtcc atgagttaat caggtactgg
     3421 aaagcaccgc gaacctgacc aaaaacgttg gtaatctgcg tcatcaggcc gagcgtaatc
     3481 gtaccggcaa caattgacgg aaacagcaag aacaaaccga aaacgttatc gacctgcaaa
     3541 tagagaatgc gggcgatgtt gaaatacata tagtgaaaat agaggcggaa atagtttttc
     3601 cgcacggcgc taaacagctc gcgtaccgta ggcggcgtcg cacgcgtggc atcgtcttca
     3661 ccataaacca gctctttacg gtaggcggcc tctactcgct ggtttttaaa ctccagcccc
     3721 ggcagtttga tccctaccac tgccagcaat ccggtcccca tcagcgacca gacgatagcg
     3781 gcaatcacca gaccatacgg aatgtgcccg ataatcggca gctccggcac atgcgtggag
     3841 agcgttacca gcaccggcag gaaggcgatc aacgtcatga tggcgttgat aaaactgacg
     3901 cccatattct ccagcgttga agcaaaacgc atggtgtctt cctgcacacg ctgtgcggcc
     3961 ccttcgatat gacgcagttg ttgccagttc gccatgtaat attcgttcat cgccgtacgc
     4021 cagcggaaca cgtagtgact gacaaagaag ttgttcagca cactgatcac cacagcgatc
     4081 agcgcaatcc ccagaaagac gcccacttcg cggtaaaatt gttcgatagt gactttatgc
     4141 ggcgaactta gcgcggtttg aatcagatca tagaacggtg cataccaggc gttgacggcg
     4201 accccgactt ccaccaaaaa ccaggtgacg aagatgatca gtgcagtacc gagtattgac
     4261 cagtattgcc aacggtgcgg gctgtagata aaccagaaaa atgcaaaaag tcctacgcaa
     4321 acaatgtagt aagcgtaaaa aatcaggaaa tccaacgacc agaaacgcgc ggcgctaatc
     4381 gggatctgcc cggaagcgcc agtgatacgc gccacccact ctcccccacc ggcttgccag
     4441 aagataacgg caatcaatgc ccaaacaaag gccgagagaa aaaacgctcc cggctttggg
     4501 aaaaaagact taaacatatg cactcctgct aacttcttat cgttttaaca actgctgtgt
     4561 attaaccgca tgaccgctac aaagcgtcag ccaaatgaaa ccgcccattg tgacccatag
     4621 caaggcgctt agttcgccag cctgaccata agaattgttt cgacggattt cacaaaccaa
     4681 agattgttta cataagcgga ttaacacgcg caggatcaca aatgcaggca ttggtgagca
     4741 ggaaaaagat cgtgtttacg cgccgttacg tttttaacac tattattgca ctaattcgcc
     4801 ctttgcaatc catcaatgag tagtataaat acgctcagtt accttcattc aatctatgga
     4861 caccaccgtt gaaacgtagt ctgctttttt ctgccgtgct gtgtgcggcg tcattgacct
     4921 ccgtccatgc ggcgcagccg atcactgaac cggagtttgc ctctgatatt gtcgatcgtt
     4981 atgccgatca tattttttac ggcagcggtg ccacggggat ggcgctggtt gttatcgacg
     5041 gtaaccagcg cgtctttcgc agttatggcg aaacgcgacc tggtaataac gttcgcccgc
     5101 agctggattc ggtcgtgcgt attgcttccc tcaccaagct aatgaccagt gaaatgctgg
     5161 tgaaattgct cgaccagggg accgtgaagt taaacgatcc gctaagtaaa tatgctccgc
     5221 caggcgcacg cgtgccaacc tacaatggga cgcccattac cctagtgaat ctggcaaccc
     5281 ataccagcgc cctgccccgt gaacagcccg gtggcgcggc acatcgtccg gtgtttgtct
     5341 ggccaacgcg cgagcaacgc tggaaatacc tttctacggc gaagctgaaa gccgcgccag
     5401 gcagtcaggc ggcgtactct aaccttgcgt tcgacctgct ggcagatgca ctggcgaatg
     5461 cgtccggcaa gccttatacc cagttgtttg aagagcagat tacccgtcca ttggggatga
     5521 aagacaccac ctacaccccc tcaccggatc agtgccgccg tttaatggtt gctgagcgcg
     5581 gtgccagtcc gtgcaataac acgctggcgg caattggcag cggcggcgtc tattccacgc
     5641 ctggcgatat gatgcgctgg atgcagcagt atttgtcatc tgatttttat cagcgcagta
     5701 accaggcaga tcgcatgcag acgttgattt atcagcgcgc gcagtttacg aaagtgattg
     5761 gcatggatgt ccccggcaaa gcggatgcgc ttggtttagg ctgggtatat atggccccga
     5821 aagagggtcg tccggggatt attcagaaga caggcggtgg tggcggtttc attacctata
     5881 tggcgatgat cccgcagaag aatattggcg cgtttgtggt ggtcactcgt tcgccgttga
     5941 cgcgctttaa aaatatgagc gatggcatca atgatctggt gaccgagcta agcgggaata
     6001 aaccgttggt tatccccgca tcctgattaa tactctgaag gcaaacggtt gatagcgacc
     6061 agtttgcctt tattcatttc gatatagccg cctttacgca aagcagcgag aacttctgcg
     6121 acgacagaac gcgatatgcg tgtacgttga tggatataat tcatcacacc aatacgtgat
     6181 cgcaattctt cattccagtc aatcattgat aataatgttg cgcggatttg ttcgtaggaa
     6241 ttatgcccaa tgagctgcac gtcgcgtaat tccagaattc tattttgcca ggctaaccag
     6301 taaaaagcgt ctcgccagag ttgattttgt tcaataagcg taatggtttg tttggctggt
     6361 agatgatatc ccgtacaatt tccttctgat attaatttgt atggtatatc gtttttcatt
     6421 aaaccatcag ccagccccat aatataagga gcctgggtaa taccgataag tacgttttct
     6481 tctctacgca gagagataac gccctctaaa ataacgaaag tatcttcgtt attgacatca
     6541 ctggaaaata taacttgctt ttcattatta aactcgaagc gcgtaccgta tctggacaaa
     6601 catttatcga gcttaccaaa ttcctgaaga ggtttaacta cagataacat ttgcgcgtcc
     6661 tttgcagtaa tgcccgtcaa atccttgacg ggcattattt agattaaatt accagaattt
     6721 cttcggagtg aagaatatta ccaggtatat ttaacaccca cgttcgcgga ccagtcttga
     6781 tctacgtcac caccaccgag gtagttagca tcggtatagg cgctgaagtt cttggtgaag
     6841 ctgaactgag tacccagacc aacacgtacc gcagaccctt cagtaccgtt atcgatggaa
     6901 tcaccgttca catcgttatc gttgttagag tcgtcgtaga cgtaagccag tttgaagtac
     6961 ggagtcagag cctggtcttc gctgtaggtg aaggtataac ctgcatctac acccagttca
     7021 taacgcatgc tgtcgtaaga ctgaccgtca actttcatgt cgttgctcag ctggtagtca
     7081 tcaccagact ggaacagacc agaaatgctg ccgtaaggag tcacgtaacc agcatcaccc
     7141 agtttgaagt cgtaaccggc tttcaaaccg aagccccaag cgtcggagtt ggtgctaccg
     7201 tcaacgtaag taccgttgct catggttgca gacaggtcgt tgttgaagtg agagtaactc
     7261 aagctaccat caacaaagac gttgttcgcg aagtgagcag aagagtagat gtaggcagtc
     7321 tggctgtctt gatccacctg accagaacgg tcattcatgt cacctttagc gaagcctgca
     7381 gccgcaccga cgatccactt agcgttgtta ccgtcaattt tggtatcaac accgaccatg
     7441 atgccgttaa catcctgatc atagttgatg gtgccgttgt cgccgttgaa gttaccaccg
     7501 aagtagctta cccatgcgcc gccgttatca gccaggccat gacgagagtt ggtcagacga
     7561 gtaccaacgg tgtcttgttc caggttccag atattggtgt tcgcagacgg gatgctcagc
     7621 gccatgttag cgtagtcggt cagctccatc tgttgcagaa caacggtgtt accgcgctgt
     7681 tcagcctgat aggtgtatgc acccaggtca gctttgttag cagcagagaa ggtcgcgttg
     7741 gtgttgacgt cgtttacgta gataatttct ttatctttgt aatcagcgat agcgccagcg
     7801 cctgttgcgt tgtcgatacg aa
//
LOCUS       DAZUDJ010000131         7805 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.133, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000131 DAZUDJ010000000
VERSION     DAZUDJ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7805
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.133"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..1043
                     /locus_tag="ACHY1N_004730"
                     /pseudo
     CDS             1..1043
                     /locus_tag="ACHY1N_004730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418441.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ShET2/EspL2 family type III secretion system
                     effector toxin"
     gene            complement(1012..2748)
                     /gene="aceK"
                     /locus_tag="ACHY1N_004731"
     CDS             complement(1012..2748)
                     /gene="aceK"
                     /locus_tag="ACHY1N_004731"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008772 - [isocitrate dehydrogenase
                     (NADP+)] kinase activity [Evidence IEA];
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HFS4046898.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDL
                     PLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSG
                     TLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRV
                     FKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMEL
                     LLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRR
                     QRFSVRYGEMLF"
     gene            complement(3029..4333)
                     /gene="aceA"
                     /locus_tag="ACHY1N_004732"
     CDS             complement(3029..4333)
                     /gene="aceA"
                     /locus_tag="ACHY1N_004732"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004451 - isocitrate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HFS4046899.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLA
                     ASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF"
     gene            complement(4363..5964)
                     /gene="aceB"
                     /locus_tag="ACHY1N_004733"
     CDS             complement(4363..5964)
                     /gene="aceB"
                     /locus_tag="ACHY1N_004733"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004474 - malate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006097 - glyoxylate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HFS4046900.1"
                     /translation="MTEQATTTDELAFIRPYGEQEKQILTAEAVEFLTELVTHFTPQR
                     NKLLAARIQQQQDIDNGTLPDFISETASIRDTDWKIRGIPADLQDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQS
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDEERNNQVLNKVKADKALEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEV
                     MREQDVPITADQLLASCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHQKTLSNGKPVTKALFRQMLGEEMKVIASELGEERFSQGRFDDAA
                     RLMEQITTSDELIDFLTLPGYRLLA"
     gene            complement(6233..7162)
                     /gene="metA"
                     /locus_tag="ACHY1N_004734"
     CDS             complement(6233..7162)
                     /gene="metA"
                     /locus_tag="ACHY1N_004734"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HFS4046901.1"
                     /translation="MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLGPEVPYNYFPHNDPQNTPRAS
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
     gene            7319..7762
                     /locus_tag="ACHY1N_004735"
     CDS             7319..7762
                     /locus_tag="ACHY1N_004735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFS4046902.1"
                     /translation="MVISIRRSQHEEGEELVAIWCRSVDATHDFLSAEYRAELEELVR
                     SFLPEAPLWVAVNERDQPVGFMLLSGQHMDALFIDPDVRGCGVGRMLVEHALSMAPEL
                     TTNVNEQNEQAVGFYKKVGFKVTGRSEVDDLGKPYPLLNLAYVGE"
BASE COUNT         1950 a         1953 c         1971 g         1931 t
ORIGIN      
        1 gattactctt cagctgaaaa atttctcacg cacttcaaca aaaaatgcaa aaaccagact
       61 ttggcgttgg tttccagccg tcctgagggg cgttgcgttg ctgcctgcgg tgatttcggg
      121 ctagttatga aagcatattt tgacaagatg gaatcaaatg gcatcagtgt tatggcagcc
      181 atattactgg tggataacca tgctttgacg gtccggctaa gaataaagaa cacaactgaa
      241 ggatgtaccc attacgtggt ttcggtttat gatcctaatg taactaacga taaaataaga
      301 attatgagcg aaagcaaaga ggatattaaa cactattctc tgatggattt tatgaatgta
      361 gattatagcc tcctgaaatg gtcaaatgat catgttatta accaatctgt tgcaataatt
      421 ccagcacttc cgaaagaaca gctattgatg ttaaaaggat ctgtggatga aataacccct
      481 ccattatcac cagcaacgat gaatttgcta atggcaattg gtcagaatca ccaacttacg
      541 caactgatga ttcaactcca gaaaatgcca gaactacata gaacagaaat gttgactgcc
      601 tataatagtg gacatatgaa cgttattaat actattttta acgcattacc cactcttttt
      661 aatacgttta aattcgataa aaaaatatga agcccctcct cctggcaaat aattctaatg
      721 aatatcccgg tttgttttca gcgatacagc ataaacaaca aaacgttgta gagacggttt
      781 atcttgcttt atctgaccat gcacgcctgt ttggatttac cgctgaagat attatggatt
      841 tttggcaaca caaagcgcca caaaaatact ctgcctttga gttggctttt gaatttggtc
      901 accgggttat tgctgaatta atccttaata cattaaataa gatggctgaa agctttggct
      961 ttacggataa ccctcgatac attgcggaga aaaattatat ggaagcttta ctcaaaaaag
     1021 catctcccca taccgtacgc taaatctttg cctgcgccga tacgcataaa catcttccac
     1081 atgcccttca cgtatgcggt tttgtagtgc gcgccagtaa tcagcgcgga acaggtcggc
     1141 gtgcatctct tcaaacagcg gaccaatacg cgggtcggcg catagccagt ggcgaaactc
     1201 ttccgggaaa acatcgcccg gcgagacgct gtaccacggt tcgctggcaa gttcgtcttc
     1261 cggatagcgc ggcggcggga tgtcgcggaa attcacttcc gtcatgtagc aaatttcatc
     1321 gtaatcataa aaaaccacac gcccgtgacg ggtgacaccg aagtttttaa acagcatgtc
     1381 gccaggaaaa atgttagcag cggcaagctg gcgaatagcg ttaccgtatt cttcaatggc
     1441 gtcgcgcaac tgctgacctt ccacttgttc cagccagata ttgagcggca ccatccgccg
     1501 ctcgatatag agatggcgaa ttacaatctg ctcaccaaga tcggtgattt tttccgctgc
     1561 ttcctggagc agtaattcca ttaatgccgg ggaaatatgc cgcttctcca gcacaaagtt
     1621 ttcaaactcc tgggtgtccg ccattcggcc cacgcgatcg tgctctttca ccagttgata
     1681 gcaggcacga acgtgagcgg cagacatctc tttctgcggc gcgaacttgt ctttgatgac
     1741 tttgaatacc cgatcaaagc ccggcagcgt aaacaccaac atcaccattc cacgaatacc
     1801 cggcgcttca atgaactgct cattacagcc ctgtagataa acgagatatt cgcggtagct
     1861 ttcggttttg gcgtgcttct ggcagccgat agccatatac aattcagcag tggttttacc
     1921 tggcagaatt tcccgtagcc actcgaccag cgctgcgggc agcggtgcat aaaccataaa
     1981 ataagaacgc gcaaagccaa aaacaatgct cgcttcggcg gtcgtcgtca ggcaggtatc
     2041 aataaataac tcgccgtcgt ccgtctggtg gatcggcagt aagaagggca acgtgccgga
     2101 aggcgtgatc agtttgccca ccagccaggc ggctttattg cggtaaaaca gttcgttcgc
     2161 cacctgtaaa tgactttccg cgaggttgtc tgtccccagc gtttccgtca gatggcgaat
     2221 gatgtaatga atgtcacggc ttttattctg ccagcgcagg cgcagcggca ggtcgctgat
     2281 aacgcgcatc agtagagatt cccagccgtg atcggggtga aagtctttcg ccagcgggcg
     2341 gggaatggta cgaaagcggc gctctggctg agagctaaag ataaaaagcc gctcgggagt
     2401 aagcgagcgg tggtcaaata accgacagta cacggagtta aaaaagctct ccgcaatctc
     2461 gaagcgcggg taatccggca acagccgcgt gtaatgctct ttaacgcgca gtaaaaatgc
     2521 cgcgtccgta ctttggccgt tagtaatgca gcgcagttgc tccacgacca gaccaacgtg
     2581 atgatcgtaa agatggatac ggtttttcat cgcctgctgg acagcatgcc agtcggcctg
     2641 ttcgaaacgc tgctgcgccc cggaagtcac ttcgaggaat cgaccatact gagcgtcgaa
     2701 gccttgcaaa atggtttgag caatcagtaa ttccaggcca cgcggcattt agcgccctca
     2761 tcaggagcag agaattgccg gatgcggcgt aaacgcctta tccagcctac gttcggcaac
     2821 ggttgtaggc atgataagac gcgcaagcgt cgcatcaggc atcgtgcacc gattgccgga
     2881 tgcggcgtaa atgccttatc cggcctacgt tcggcaacgg ctgtaggcat gataagacgc
     2941 gcaagcgtcg catcaggcat cgtgcaccga ttgccggatg cggcgtgaac gccttatccg
     3001 gcctacagtc agcaacggtt gttgttgctt agaactgcga ttcttcagtg gagccggtca
     3061 gcgcggtgac tgaagacgtg ccgccctgaa taatagtcgt cactttatcg aagtaacctg
     3121 tacccacttc ctgctggtga gatacgaagg tatagccatc tttcgcggcg gcaaattccg
     3181 gctgctgcac tttctcaacg tagtgcttca taccctcgcc ctgggcatag gcgtttgcca
     3241 ggtcaaacat gttgaaccac atgctgtgga tacctgccaa ggtgatgaac tggaacttgt
     3301 agcccatatc cgacagctgc tgctggaagc tggcaatagt tttgtcgtcg aggtttttct
     3361 gccagttgaa cgacggcgag cagttataag ccagcagttt gcccggatat ttcgcgtgga
     3421 tagcttgtgc aaagcgacgc gccagttcca gatccggcgt ggaggtttca caccagacca
     3481 ggtcagcata tggcgcatac gccaggccac ggctgatcgc ttgctcaatg cccgcatgag
     3541 tacggaagaa gccttcactg gtacgctcgc cagtaataaa ttcactgtca tacgggtcgc
     3601 aatcggaggt aatcagatcc gccgcatcgg catcggtacg agcaaccagc agggttggaa
     3661 cgcccgtcac gtcagctgca agacgcgccg cgaccagttt ctgaatagct tcctgagttg
     3721 gcaccaaaac tttgccgccc atgtgaccgc atttcttcac tgacgccagc tgatcttcga
     3781 agtgaactgc cgctgcaccg gcttcaatca tcgctttcat cagttcaaag gcattcagga
     3841 caccgccaaa accggcttcc gcatcggcaa cgatcggcag gaagtaatcg acatagcgcg
     3901 gatcgcccgg ctcaatgcct gcggaccatt ggatctgatc ggcacgacgg aaggtgttgt
     3961 tgatccgctc caccacagct ggcaccgagt ttgccggata gagcgactga tccggataca
     4021 tgctggccgc caggttagcg tccgccgcta cctgccatcc cgacagatag actgcttcaa
     4081 tacccgcttt cgcctgttgc agcgcctgac cgccagtcag tgcaccgagg ctgttgatgt
     4141 agcctttttt cgactcgcca tgcagcagac gccacatttt cgccgcgccc agttgcgcca
     4201 gggtgcattc aggattgact gaaccgcgta atttcaccac atcttccgcg ctgtatgggc
     4261 gagtaatgcc ttcccaacgc ggttgagtcc actctttctg taattcttca atttgttgtg
     4321 tacgggtttt catgtgcaga tgctccatag ttatgtggtg gtttacgcta acaggcggta
     4381 gcctggcagg gtcaggaaat caattaactc atcggaagtg gtgatctgtt ccatcaagcg
     4441 tgcggcatcg tcaaaacgcc cttgggagaa acgttcttcg cccagttcgc tggcaatgac
     4501 tttcatctct tcacccagca tctggcggaa caaggctttg gtcaccggtt tgccattgct
     4561 caacgttttt tgatgatgga tccactgcca gattgaggta cgggaaattt cagccgtcgc
     4621 cgcatcttcc atcaggccat aaatcggcac gcagccgttg ccggagatcc atgcttcgat
     4681 gtactgcact gccacgcgaa tgttggcgcg cataccttct tcggtgcgtt caccatcaca
     4741 agatgccagc agctgatcgg cagtaatcgg cacgtcttgt tcgcgcatca cttcaagctg
     4801 atttttacgg gagccgagaa tgtcgttgaa taccgccatt gccgtatccg caaggcctgg
     4861 gtgagcaatc catgtgccat cgtgaccgtt attggcttcc agcgctttat ccgcttttac
     4921 tttgttgagc acctggttat tgcgctcttc atctttgctc ggaataaacg ctgccatgcc
     4981 gcccatcgca aaagcaccgc gtttatggca ggttttaatc aacaggcgtg agtaagcatt
     5041 caggaatggt ttatccatcg tcactgcctg tctgtctggc aggacgcgat cgggatagtt
     5101 tttcaacgtt ttgatatagc tgaagatgta atcccaacga ccgcagttca gaccaacaat
     5161 atggtcacgc agcgcgtgaa ggatttcatc catctggaac acggcgggca gcgtttcaat
     5221 cagcaacgtc gccttgatgg tgccgcgcgg cagattaaag cgatcttctg catagctgaa
     5281 gacttcgctc caccaggccg cttcctgcca ggactgggtt ttcggcagat agaaataggg
     5341 accgctgccc tttgccaaca gtgcctgata gttgtggaag aaatagagcg caaaatcaaa
     5401 caggctaccg gggattgcct caccacgcca ggtgacatgt ttttccggca agtgcagacc
     5461 gcgtacccga caaatcaaaa ccgctggatt gggcttgagc tgataaattt tgcctgcttc
     5521 attggtatag ctgatggtgc cgttaaccgc atcgcgcagg ttaatttgcc cgtcgatcac
     5581 tttgttccag tctggtgcca gtgaatcttc gaaatcggcc ataaagactt tcacattggc
     5641 gttcagtgcg ttgatcacca tcttgcgctc aaccgggcca gttatctcga ctcgacgatc
     5701 ttgtaagtcc gcgggaatac cacgaatttt ccagtccgta tcgcgaatgg aagctgtttc
     5761 cgaaataaaa tcaggcaaag ttccgttatc aatatcttgc tgctgctgaa tgcgcgctgc
     5821 cagaagttta ttgcgttgtg gcgtaaaatg cgtcaccagc tcagtcagaa attctaccgc
     5881 ttcggcagta agaatttgct tctcctgctc gccatacggc cttatgaaag ccagttcatc
     5941 ggttgttgtt gcctgttcag tcatcgtgca gctcctcgtc atggatccga aaacttcccc
     6001 actgtgaacg aaggatcgtt gtgcgctttt cgttcagcac aactaagact actcatttaa
     6061 aatgcaaaat caaaaacaat ttccatttta attaaaaata cttgataact tattgataac
     6121 aatatgaata aaatttattc acctcctgag gtgcgtttcg gaaataaaaa aggcacccga
     6181 aggtgcctga ggtaaggtgc tgaatcgctt aacgatcgac tatcacagaa gattaatcca
     6241 gcgttggatt catgtgccgt agatcgtatg gcgtgatctg atagacgtaa tagttgagcc
     6301 agttggtaaa cagcaaatta ccgtgactac gccagctcgc tcgcggtgta ttttgcggat
     6361 cattgtgcgg gaaatagtta tacggtactt ccgggcctag tccggcttcc acatcgcgga
     6421 aatattcctg cgccagcgtt tgcgcatcat attcgggatg gcccgtcaca aaggcaatgc
     6481 gcttatcttt gctggcaaac agatatgcat ccccttcttc cgtctctgcc agaatttcca
     6541 gatcggtgta atcacgaatc aacgctgccg gaaagtcagc atagcgcgaa tgtggtgcca
     6601 ggaatgaatc atcaaagcca cgcgtcagaa gcgcatgagg atggagaata tgatgctcgt
     6661 aaacgccaga gagtttgtcg gtgcgagttt gcttaggaat gccgtagagg atattgagcg
     6721 cggcctgtac cgcccagcag acaaacagcg tcgaggtgac gtgatctttc gaccactcca
     6781 gcacctgttt gatctgcggc cagtaagcga catcattaaa ctccaccagg cccagcggcg
     6841 caccggttac aatcagaccg tcaaagttct gttcctgaat atcttcaaag ttacagtaga
     6901 agttgttcag atgctctgcg ggcgtgttgc gcgattcacg ggaatcgatg cgcaacagct
     6961 gaatatcgac ctgcaaaggt gagtttgaaa gcaggcgcag aaactgattt tcagtttcaa
     7021 tcttcttcgg catcaggtta aggatcagaa ccttaagtgg acgaatttcc tgaccagacg
     7081 cacgagaagt tgtcatcaca aagacgtttt cttcacgcaa gaaattgacg gcgggtagct
     7141 cgtccggcac acgaataggc ataacctgat tacctcacta catacgctta tacgtttaga
     7201 catccagata gctgaagata accagaaaat ttgccaatgt cgagcctgca tgttgaaggt
     7261 gagaaagttt caaggaaaag gctacgttag aatataagaa tgacgaaaag gagagaaaat
     7321 ggttattagt attcgccgct cacagcatga ggaaggggag gaactcgttg cgatttggtg
     7381 tcgatctgtc gatgccaccc acgatttttt atcagcagag tatcgggccg agctggaaga
     7441 gctggttcgt tcctttctgc cggaagcacc gttgtgggtc gcggttaatg aacgggatca
     7501 gccggttggg tttatgttgt taagtgggca gcatatggat gcgctgttta tcgatcctga
     7561 tgtgcgcggc tgcggcgtgg gtcggatgct ggtggagcat gcgctctcga tggcaccgga
     7621 actgacaacc aacgttaatg agcaaaatga gcaggcggtt gggttctata agaaggtggg
     7681 ttttaaggtt acgggacgct ctgaggtgga cgatttgggg aaaccgtatc cgttgctgaa
     7741 tctggcgtat gtgggggaat aagccgcccc tgccgtgcct gcccaggctg gagaagacgc
     7801 gccag
//
LOCUS       DAZUDJ010000132         7802 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.134, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000132 DAZUDJ010000000
VERSION     DAZUDJ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7802
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.134"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            288..1703
                     /gene="gltX"
                     /locus_tag="ACHY1N_004736"
     CDS             288..1703
                     /gene="gltX"
                     /locus_tag="ACHY1N_004736"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFS4046903.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSK
                     ERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALK
                     APVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEI
                     FTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDT
                     RNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVR
                     DKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALDFIAERENQQ"
     gene            complement(1755..2147)
                     /locus_tag="ACHY1N_004737"
     CDS             complement(1755..2147)
                     /locus_tag="ACHY1N_004737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416898.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeC-like transcriptional regulator"
                     /protein_id="HFS4046904.1"
                     /translation="MKRLRNKMTTEELAECLGVAKQTVNRWIREKGWKTEKFPGVKGG
                     RARLILVDTQVCEFIQNTPAFHNTPMLMEAEERIAEYAPGARAPAYRQIINAIDNMTD
                     IEQEKVAQFLSREGIRNFLARLDIDESA"
     gene            complement(2149..2508)
                     /locus_tag="ACHY1N_004738"
     CDS             complement(2149..2508)
                     /locus_tag="ACHY1N_004738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeC-like transcriptional regulator"
                     /protein_id="HFS4046905.1"
                     /translation="MFKERMTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKA
                     RLVHVNEQVREYIRNAERPEGQGEAPALSGDAPLEVLLVTLAKEMTPVEQKQFTSLLL
                     REGIIGLLQRLGIRDSK"
     gene            2729..2804
                     /locus_tag="ACHY1N_004739"
     tRNA            2729..2804
                     /locus_tag="ACHY1N_004739"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2762..2764,aa:Ala,seq:ggc)
     gene            2844..2919
                     /locus_tag="ACHY1N_004740"
     tRNA            2844..2919
                     /locus_tag="ACHY1N_004740"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2877..2879,aa:Ala,seq:ggc)
     gene            3127..5316
                     /locus_tag="ACHY1N_004741"
     CDS             3127..5316
                     /locus_tag="ACHY1N_004741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416896.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MASE1 domain-containing protein"
                     /protein_id="HFS4046906.1"
                     /translation="MFVEHNLIKNIKIFTLAFTLTVILIQLSRFISPLAIIHSSYIFL
                     AWMPLCVMLSILFIFGWRGVVPVLCGMFCTNLWNFHLSFLQTAVMLGSQTFVVLCACA
                     ILRWQLGTRWRYGLTSRYVWQRLFWLGLVTPIGIKCSMYLVGSFFDFPLKISTFFGDA
                     DAIFTVVDLLSLFTAVLIYNMLFYYLTRMIVSPHFAQILWRRDIAPSLGKEKRAFTLS
                     WLAALSVLLLLLCTPYENDFIAGYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLN
                     YNQNFLQGVETEYSLAFILAVLISFSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLL
                     PNFRALEQAPEQEAGKSFCCLRIDNLEFMSRHYGLMMRVHCIRSICRTLLPLMQENEK
                     LYQLPGSELLLVLSGPETEGRLQHMINILNSRQIHWNNTGLDMGYGAAWGRFDGNQET
                     LQPLLGQLSWLAEQSCAHHHVLALDSREEMVSGQTTKQVLLLNTIRTALDQGDLLLYA
                     QPIRNKEGEGYDEILARLKYDGGIMTPDKFLPLIAQFNLSARFDLQVLESLLKWLATH
                     PCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRYHISPQAVILEITEEQAFSNAESSM
                     YNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADIIKIDGVFVKDIVTNTLDAMIVRS
                     ITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYLIGRPQPLAD"
     gene            complement(5366..6568)
                     /gene="nupC"
                     /locus_tag="ACHY1N_004742"
     CDS             complement(5366..6568)
                     /gene="nupC"
                     /locus_tag="ACHY1N_004742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HFS4046907.1"
                     /translation="MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     ISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            6904..>7802
                     /locus_tag="ACHY1N_004743"
     CDS             6904..>7802
                     /locus_tag="ACHY1N_004743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFS4046908.1"
                     /translation="MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAY
                     LTLQPLLSHAAATVFGLSLVAAGL"
BASE COUNT         1894 a         1837 c         1996 g         2075 t
ORIGIN      
        1 aggtgctctc ccagctgagc taatcacccc cgctgtgtgg agtcgcatta tagggagagt
       61 tcaaaatgag tcaacgcatt ttctaaagaa attgttcgtt cgtcgtaaat ttaagcaaga
      121 tgatcgcaaa acagaccgtg ttgcgcaatt tgtcaacgaa aacaataatg cgtaaggtag
      181 aaacccgaac tacattgagg aatcaggcgg gagtgataga atatcgccca ctcaattttt
      241 ccaggatttg ccggttgtcg gcatctttct aaacgtaagg ccatttcatg aaaatcaaaa
      301 ctcgcttcgc gccaagccca acaggctatc tgcacgttgg cggcgcgcgt actgctcttt
      361 actcctggct ttttgcacgt aaccacggcg gtgagttcgt gctgcgtatt gaagacaccg
      421 atcttgagcg ttccacgccg gaagctatcg aagccattat ggatggcatg aactggctga
      481 gcctggagtg ggatgaaggt ccgtactacc agaccaaacg ttttgatcgc tacaatgcgg
      541 tgatcgatca gatgctggaa gagggcactg cttataaatg ctattgctct aaagagcgcc
      601 tggaagcgct gcgcgaagag caaatggcga aaggtgagaa gccgcgttat gacggtcgct
      661 gccgccacag ccatgagcat catgctgatg atgaaccgtg tgtcgtgcgt tttgctaatc
      721 cgcaggaagg ttctgttgtt tttgacgatc agatccgtgg tccgatcgag ttcagcaacc
      781 aggagctgga tgatctgatt atccgccgta ccgatggttc cccaacctat aacttctgtg
      841 tggttgtcga tgactgggat atggaaatca cccacgttat ccgtggcgaa gaccatatca
      901 acaacacgcc gcgccagatc aacattctta aggccctgaa agcgccggtg ccggtttacg
      961 cgcacgtttc tatgatcaat ggcgatgacg gtaaaaaact gtccaaacgt cacggggcag
     1021 tcagcgtaat gcagtatcgt gatgacggtt atttgccaga agcactgctg aactatctgg
     1081 tgcgtctggg ctggtcccac ggcgatcagg aaatcttcac tcgtgaagag atgatcaaat
     1141 acttcacttt gaatgccgtc agcaaatctg ccagtgcgtt caacaccgac aagctgctgt
     1201 ggctgaacca tcactacatt aacgcgctgc cgccggagta tgttgctact cacttacagt
     1261 ggcacattga gcaggaaaat atcgataccc gtaacggccc gcagctggct gatctggtga
     1321 aactgctggg cgaacgctgc aagacgctga aagagatggc acagagctgc cgttatttct
     1381 acgaagattt tgctgagttc gatgccgatg cggcgaaaaa acatctgcgt ccggtagcgc
     1441 gtcagccgct ggaagtggtt cgtgacaaac tggccgcgat tactgactgg accgctgaaa
     1501 acgttcatca cgctattcag gcgacggcgg atgagctgga agtgggtatg ggtaaagttg
     1561 gtatgccgct gcgtgtcgcc gtaaccggtg cggggcagtc tccagcactg gatgttaccg
     1621 ttcacgcaat tggtaagacc cgcagtatcg agcgtatcaa caaagcgctg gattttattg
     1681 ctgaacgcga aaatcagcag taattagcgt gtaaaaagat aaacggcagg agataatatc
     1741 ctgccgtttt ttatttatgc tgattcgtca atatcgagac gggcgaggaa attgcgaatt
     1801 ccttcacgtg acaaaaattg cgcgactttt tcctgctcaa tgtctgtcat attatctatc
     1861 gcgttgatga tttgtcgata cgccggggcg cgtgctccag gagcgtattc agcaattctc
     1921 tcttcagctt ccatcaacat tggtgtgtta tggaaggctg gcgtgttctg aataaactcg
     1981 caaacttgcg tatcgaccag aataagtctg gcacgaccgc ctttcacgcc gggaaatttt
     2041 tccgttttcc agcctttttc tctgatccaa cggttaacag tttgtttagc cacaccgagg
     2101 cattcagcca gttcttcggt ggtcattttg ttgcgtaatc ttttcatatt atttgctatc
     2161 gcgaatccct aagcgttgta acaatccgat aatcccttcc cgcagaagca aggatgtaaa
     2221 ctgtttttgt tcaactggcg tcatctcttt cgccagtgtc accagcaata cttcaagcgg
     2281 cgcatcacca gaaagggcag gcgcttctcc ctgaccttct ggacgttcag cattgcgaat
     2341 atattcacga acctgttcat tgacgtgaac cagtcgggct ttgccaccct ggacgccagg
     2401 ttttggtgac gttgtccagc cttccttgcg tacccattta ttaatggtct ggcggctata
     2461 gccggtcagt ctggcaagtt catctggtgt catcctctcc ttgaacataa caattccctg
     2521 aatgtatgtg ggtctattag tagttcattt tataacacca ctttacagga aaccgtgaca
     2581 tgaataacta ctgaatgcga gcggttttcc aaaattgttc atttgcctga tttttcagcg
     2641 attgaaatta cacgttgcaa tttgccgttg acacattcgg gcggaattta tatgatgccg
     2701 cccgtcaact cgacaagctt tacgtgacgg ggctatagct cagctgggag agcgcttgca
     2761 tggcatgcaa gaggtcagcg gttcgatccc gcttagctcc accaaatttt gcacccagca
     2821 aatttggtac gtaaacgcat cgtggggcta tagctcagct gggagagcgc ttgcatggca
     2881 tgcaagaggt cagcggttcg atcccgctta gctccaccaa atttccaacc ctcgctgcaa
     2941 agcgggggtt ttttgtctct gctttttgcc gcttttgtca tacagtctac gtccgggtta
     3001 gcgccgcctg gtgaaagcat cattggatga aaaatcggca acaggctggc ccctgtttgc
     3061 ttcgcgatgc gaataaactt attatttgtg tgcctgaaaa ccccgatcag tgagagtagt
     3121 gtactcatgt ttgtggagca taacctgata aaaaatatca agatattcac actagcgttt
     3181 acgctcaccg tgatacttat tcagctatcc cgttttattt cgccacttgc cattatccat
     3241 tccagttata tctttctggc gtggatgcca ctgtgcgtaa tgctgtcaat cttgtttatc
     3301 tttggctggc gcggtgtcgt tcccgtttta tgcgggatgt tttgcaccaa tctgtggaac
     3361 tttcatctct cttttttaca gactgcggtc atgctcggta gccagacgtt tgtcgtgttg
     3421 tgtgcctgcg caatattacg ctggcagctg gggacgcgtt ggcgttatgg attgaccagc
     3481 cgatatgtct ggcaacgtct gttctggctt ggtttggtga cgccgatcgg catcaaatgc
     3541 agcatgtatc ttgtggggag cttctttgat ttcccgctaa agatatccac ctttttcggc
     3601 gatgcggatg ccattttcac ggtcgttgat ttgctaagcc ttttcaccgc tgtgctgatt
     3661 tacaacatgc ttttctacta tctcactcgc atgattgtaa gtccccactt tgcgcagata
     3721 ttgtggcgca gggatatcgc gccgtcgttg ggcaaagaga aacgcgcatt taccttaagc
     3781 tggctggcag cgttaagcgt gcttctactt ctgttgtgca caccttatga aaacgacttt
     3841 attgccggtt acctggtacc cgttttcttc atcatcttta ccctcggggt cggtaagctt
     3901 cgctatccgt ttttaaatct cacctgggct gtttcaacgc tttgccttct gaattacaac
     3961 cagaactttt tgcaaggggt ggaaaccgaa tattcgctgg catttattct tgcggtgctg
     4021 atttccttta gcgtttgcct gctctatatg gtgcgcattt atcatcgcag tgaatggctt
     4081 aatcgccgct ggcatttgca ggcgctgaca gatccgttaa cgctcctacc caactttcgt
     4141 gcgttggaac aagcgccgga acaagaggcg ggcaagagtt tttgctgcct gcgcattgat
     4201 aatcttgagt ttatgagtcg tcattacggc ttaatgatgc gcgttcactg tatccgctca
     4261 atttgccgta cgctgctgcc gttgatgcag gaaaacgaaa agttgtatca attgccgggt
     4321 agtgaactgc tgttagtgct gagcgggccg gaaacggaag ggcgactcca gcatatgatt
     4381 aacatcctga atagtcggca aattcactgg aacaataccg ggctggatat gggctatggt
     4441 gctgcctggg ggcgttttga tggaaatcag gaaaccctgc aacccttgtt ggggcagtta
     4501 agctggctgg cggagcaatc ctgcgcacat catcatgtgc tggcgctgga tagcagagag
     4561 gagatggttt ccgggcagac cactaaacag gtgctattgc tgaataccat tcgcacggcg
     4621 ttagatcagg gtgatttgct gctctacgcc cagccaattc gcaacaaaga gggtgaaggt
     4681 tatgatgaga tcctcgcgcg actgaaatat gacggcggca ttatgacccc ggataagttt
     4741 ctgcccctta ttgctcagtt taaccttagc gcgcgttttg atttgcaagt gctggaatcc
     4801 ttgttgaagt ggctggcaac acacccttgc gacaaaaaag gaccgcgctt ttcagtcaat
     4861 ttaatgccgc tcacgctgct gcaaaagaat attgccgggc ggattattcg tctgtttaag
     4921 cgttatcaca tctccccgca ggcggtcatt cttgagatca ccgaggagca ggcgttttct
     4981 aacgcagaaa gcagcatgta caacatcgag cagctgcata agtttggttt ccggattgcg
     5041 attgatgact ttggcaccgg atatgccaac tacgaacggt taaagcgttt gcaggctgat
     5101 atcatcaaaa ttgatggcgt ctttgtgaaa gatattgtca cgaacacgct ggatgcgatg
     5161 attgtgagat caattaccga tctggcgaaa gcgaagtcat tgagtgtggt cgcggagttt
     5221 gtcgagacgc aacagcagca ggcgctattg cataagctcg gggtgcaata tctgcaaggg
     5281 tatttgattg gtcgcccgca gccattagct gattaacagg cgtaaaaaaa ccggggaatt
     5341 atccccggct tttttatgta tggtcttaca gcaccagtgc tgcgattgac gcagacagca
     5401 cactcaccag ggtagagccg taaaccagct tcagaccgaa gcgagaaacc acgttacctt
     5461 gctcttcatt caggccttta actgcacctg cgataatccc gattgaagag aagttagcga
     5521 aggaaaccag gaacacagag atgatgcctt cagcacgcgg agagagcgtg gaagcaattt
     5581 tctgcagatc catcatcgca acgaactcgt tggaaaccag tttggtcgcc atgatactgc
     5641 ccacttgcag tgcttcactg gaaggaacac ccatcaccca tgcaatcgga tagaagatgt
     5701 agcccaggat gccctggaag gagatgctgt agccaaacca gccagtaacg gtggcaaaca
     5761 gtgcgttcag cgcggcgatc agggcgataa agccgatcag catcgcggca acgataatgg
     5821 caactttgaa acctgccaga atgtattcac ccagcatttc gaagaagctc tgaccttcgt
     5881 gcaggttgga catctggatg ttttcttcac tggcatcaac acggtaagga ttgatcagcg
     5941 acagcacgat aaaggtgctg aacatgttca gtaccagcgc agcaacgacg tatttcggtt
     6001 ccagcatggt catgtatgca ccaacgatgg acatcgacac ggtggacatt gccgtggcag
     6061 ccatggtgta catacgatta cgggagattt tgccgaggat atctttatag gcaataaagt
     6121 tttcagactg acccagaatc agggagctga cggcgttaaa ggattccagt ttgcccatac
     6181 cgttgacttt ggagagcagg aaaccaattg cgcggataat aaccggcaac acgcgaatgt
     6241 gctggagaat accgatcagt gcagagataa agacgattgg gcacagcact ttcaggaaga
     6301 agaatgccag gccttgatca ttcatgctac caaagacgaa gttagtccct tcgttggcaa
     6361 atccgagcag tttttcgaac atttcggaga agcctttcac gaagcctaaa ccaacgtcgg
     6421 agttcaggaa gaaccacgcc agtaacactt cgataacaag cagttgaata acataacgga
     6481 tacgaatttt tttgcggtcg ctgcttacca gcagtgcgag aatcgcaaca acggcaagtg
     6541 ccagtacaaa atgaaggacg cggtccatat ttgctccaaa tatgaggcag gttaaatttc
     6601 cgtgcacatt ctatgtaaca tggttaagga aaacgagatc tgacacacac tataatgacg
     6661 tcctgtgaca agcttcaaaa atagtgatct gtcatacatt tctgctatgt tgtgtatgga
     6721 agctgaaagt tatgtaaatg tgctaacatt aaacataacc ataacattca aatcatcaat
     6781 cttttcgtag tcataatcct ggtctatcaa agaaatcacc acaacccatt caaatgaatt
     6841 tgataatcat tctcgtttgg catagcatga aacatagcaa aggctatgtt ttagaggcac
     6901 aagatgacga actatcgcgt tgagagtagc agcggacggg cggcgcgcaa gatgaggctc
     6961 gcattaatgg gacctgcgtt cattgcggcg attggttata tcgatcccgg taactttgcg
     7021 accaatattc aggcgggtgc tagcttcggc tatcagctac tgtgggttgt cgtttgggcc
     7081 aacctgatgg cgatgctgat tcagatcctc tctgccaaac tagggattgc caccggtaaa
     7141 aatctggcgg agcagattcg tgatcactat ccgcgtcccg tagtgtggtt ctattgggtt
     7201 caggcagaaa ttattgcgat ggcaaccgac ctggcggaat ttattggtgc ggcgatcggt
     7261 tttaaactca ttcttggtgt ttcgttgttg cagggcgcgg tgctgacggg gatcgcgact
     7321 ttcctgattt taatgctgca acgtcgcggg caaaaaccgc tggagaaagt gattggcggg
     7381 ttactgttgt ttgttgccgc ggcttacatt gtcgagttga ttttctccca gcctaacctg
     7441 gcgcagttgg gtaaaggaat ggtgatcccg agtttaccta cttcggaggc ggtcttcctg
     7501 gcagcaggcg tgttaggggc gacgattatg ccgcatgtga tttatttgca ctcttcgctc
     7561 actcagcatt tacatggcgg ttcgcgtcaa caacgttatt ccgccaccaa atgggatgtg
     7621 gctatcgcca tgacgattgc cggttttgtc aatctggcga tgatggctac agctgcggcg
     7681 gcgttccact tttctggtca tactggtgtt gccgatcttg atgaggctta tctgacgctg
     7741 caaccgctgt taagccatgc tgcggcaacg gtctttggat taagtctggt tgctgccgga
     7801 ct
//
LOCUS       DAZUDJ010000133         7783 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.135, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000133 DAZUDJ010000000
VERSION     DAZUDJ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7783
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.135"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            119..611
                     /locus_tag="ACHY1N_004744"
                     /pseudo
     CDS             119..611
                     /locus_tag="ACHY1N_004744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558155.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(678..806)
                     /locus_tag="ACHY1N_004745"
     CDS             complement(678..806)
                     /locus_tag="ACHY1N_004745"
                     /inference="COORDINATES: protein motif:HMM:NF025189.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HFS4046909.1"
                     /translation="MFFGSDHGGERGALLYGLIGTCRLNGIDPEAYLRHILSVLPE"
     gene            complement(837..1603)
                     /locus_tag="ACHY1N_004746"
                     /pseudo
     CDS             complement(837..1603)
                     /locus_tag="ACHY1N_004746"
                     /inference="COORDINATES: protein motif:HMM:NF015038.4"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(1639..2178)
                     /locus_tag="ACHY1N_004747"
     CDS             complement(1639..2178)
                     /locus_tag="ACHY1N_004747"
                     /inference="COORDINATES: protein motif:HMM:NF024408.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFS4046910.1"
                     /translation="MLTTSESQFRQKDQQLSLVEETEAFLCSALARAEEKIEEDEREI
                     EHLQTQIEKLRRMLFGTRSEKLRREVEQAEALLKQREQDSDRYSGREDAPQVPRQLRQ
                     PRHRRPLPAHLPHAIHRLESEESCCPECGGELDYLEEVSAEQLELVSSALKVIRTVRV
                     KKPVQNVTASLKHRRRPAR"
     gene            complement(2190..3342)
                     /locus_tag="ACHY1N_004748"
                     /pseudo
     CDS             complement(2190..3342)
                     /locus_tag="ACHY1N_004748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611553.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS911 family transposase"
     gene            complement(3323..3799)
                     /locus_tag="ACHY1N_004749"
     CDS             complement(3323..3799)
                     /locus_tag="ACHY1N_004749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4046911.1"
                     /translation="MELQDWRKEPRKKYSNEFKLRMVELASQPGACMAQIARENGVND
                     DVIFKWLRLWQNEGRISRRLPVTTTSDAGVELLPVEITPDEPKEPMAALTPSLSTQTT
                     VSASSCKVEFRHGNMTLENPSPELLTVKWHTEFGHLNRGDMLTSEQHRCSNEKKKF"
     gene            3886..4000
                     /locus_tag="ACHY1N_004750"
                     /pseudo
     CDS             3886..4000
                     /locus_tag="ACHY1N_004750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(4051..5560)
                     /locus_tag="ACHY1N_004751"
                     /pseudo
     CDS             complement(4051..5560)
                     /locus_tag="ACHY1N_004751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(6180..7187)
                     /locus_tag="ACHY1N_004752"
                     /pseudo
     CDS             complement(6180..7187)
                     /locus_tag="ACHY1N_004752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013747467.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1796 a         2081 c         1849 g         2057 t
ORIGIN      
        1 gtttttttat gaaatttaca gagtgcggga aacagatagc cctacgggtc agatgtttga
       61 ttaatattct catgcactca atatgctgaa taaaaataga tgagtctcct tctataacat
      121 atctgatgtg actaccccat tcgtcagtgg tcaatatacc aatgaaaaaa agagggaagc
      181 agcgccagca attcacaaca gtataggtat tgctgctgca gcccgtgagc tcagcctgta
      241 tgaatcacag tctacaactg ggtagtcaac aacaaaatca gtagacgttc ttctgaacgt
      301 gagctggaga tgtctaccga tgttgcacgt ctcaaacgcc agctggcgga acgggatgaa
      361 gagctgacca tcctccaaaa ggccgcgaca tacttcgcga agcgcctgaa atgaagtatg
      421 tctttattga aaaacatcag gctgtgttca acatcaaggc aatgtgccat gtgctccagg
      481 aaggccgcag tgactggtat atgtggtgtc agcggcggac aaggataagt acatgtcagc
      541 agttccgtca gcactgcgac agcgtggtac tcgcggcttt tatccggtca aaacagcgct
      601 acggagcacc gtattgacgc ttatttattg gtgagtacta cgttccatgg caggagttcg
      661 tcaacacggt tggagggcta ttccggtagt acgctcagaa tatggcgcag atacgcttcc
      721 ggatcgatac cgttcagacg gcaggtgccg atcagcccgt acagcagtgc tccacgctcg
      781 ccgccgtgat cgctaccgaa gaacatgtaa ttctttttcc cgagacagac ggcacgaagc
      841 gctctttccg ctgtgttatt gtccgcctcc gccagaccgt catcactgta ataacagagg
      901 gcgtcccact gattcagtac atagctgaac gcttcgcctg gtctggattt tttcgacagc
      961 gtgccattct tctccaccat ccattcatgc agcgacgtca gtaacgcttt gcttcgctgc
     1021 tgcctgactt caagacgctc tgactctggt aatccccgta tttcatcctc gatggcgtac
     1081 agttcactga tgcgcttcag ggcttcttct gccgtcgcac ttttgctgct gatgtataca
     1141 tcgtggattt ttctccggac atgggctcag cacgcaactt ctgtcagcgc accatcttca
     1201 cgttctgcac tgaacagccg atcgtaaccg ttgaacgcat ccgcctgcag ggggcggagg
     1261 tgttgctccg ggtgtttccc ctgccggttc ggtgagtacg cgaaccagac cgccggagga
     1321 gatgacgaac ccgcattgcg atcattccgg acatacgtcc agatgcgccc tgttttcgtc
     1381 ttttcaggcc cagtgccagt acctttaccg gtgtgtcgtc agtgtgaagc ttgcgggtat
     1441 tcatcacata acggtacagg gcatcattca gcggagtcat taactggcag cacgcgtcaa
     1501 cccagttgga gagtaatgca cggctcagtt cgacaccctg tcgggcaaag atttcactct
     1561 gacgatacag tggcagctgt tcgcagtatt ttcccgttaa cacgcgggca agtaatccgg
     1621 ggcccgcgat accacgctct atcgggcggg acggcgccgg tgcttcaacg atgcagtcac
     1681 attttgtaca ggctttttta cccgaacagt gcggatcact ttcagggcgc tgctcaccag
     1741 ttccagttgt tctgcactga cttcctccag ataatccagc tcaccgccac actccgggca
     1801 acagctttct tcagactcca gacggtgtat tgcatgggga aggtgtgccg gtaacggacg
     1861 acgatggcgc ggctgtctca actggcgggg aacctgtgga gcgtcttccc gcccactgta
     1921 acgatcgctg tcctgttcgc gttgtttcag cagggcctca gcctgttcaa cttcacgacg
     1981 cagtttttca gaacgggtac cgaacagcat ccggcgcagt ttttctatct gagtctgcag
     2041 atgttctatt tcccgttcat cttcttcgat cttttcttcg gcacgtgcca gtgcagagca
     2101 caggaaggcc tccgtctctt caaccagact tagttgctgg tctttctgac ggaactggct
     2161 ttctgaagtg gtcaacaaaa actggccacc tagttagagt ttttccagta tcgattttcc
     2221 gattcgtttg ggggtaaccc accgttatat tcgtgcggtc ttagtgcgct gtaatatcca
     2281 acgatatagt ccgttatggc gtgagctgcc tcgctgaagc ttacgtaacc caccaccggc
     2341 atccattcgt tctcttcaga ctcctgaaga agcgttccat tgggctgtta tcccagcagt
     2401 ttccgcgccg gctcatactc tgtctgatct ggtatcgcca caataactgc cggaactgcc
     2461 tgctcgtata atgactgccc tgatcgctgt ggaacatcac cccgccgggc ttaccacggg
     2521 tttcccatgc catttcccgc gctttcatgg tgagcctgct gtccggcgag aacgacatgg
     2581 cccagcccac tggttttctt gcgaacaggt cgagaacaac ggcgaggtac gcccagcgct
     2641 tacccgtcca gatataggtc acatcaccgc accacacctg atttggctcg gtcacggcga
     2701 actgcctttc aaggtagtta gggatagcaa catgttcatg accaccacgt ttataccggt
     2761 gagtcggctg ctgacagctg accagcccca gctctttcat gagcctgcca gcaagccagc
     2821 gtcccatctg gtagcctctc cgggttgcca ttgtggcgat gcttcttgct ccggccgaac
     2881 cgtggctgat gccatgtagc tcaagtacct gactgcgtaa tacagcccgt ctgccgtctg
     2941 gtttttcagg acggtttttc cagtatctgt agctgctgcg atgaaccccg aacacatggc
     3001 agagtgtgac cacaggataa tgcgctctga gtttcccgat tatcgagaac tgttcaggga
     3061 gtctgacatc aagagcgcgg tagccttttt taatatttca ttctccattt caatgcgttg
     3121 tagctttttc ctcagcttac gtatttcgat ttgttctggt gttatcggag aggcttttgg
     3181 tgttttgccc tgacgctcat cacgcagttg tttgacccat cttgtcattg tagaaaggcc
     3241 aacatccata gctttggcgg catctgccac cgtgtatttc tggtcaacaa ccagttgagc
     3301 ggattcgcgt ttaaactctg cgctaaaatt tctttttttc attagagcac ctgtgttgtt
     3361 ctgaggtgag catatcacct ctgttcaggt ggccaaattc agtgtgccac ttcacagtga
     3421 gcagctctgg tgaaggattt tccagcgtca tgttaccgtg acggaactcc actttgcagg
     3481 agctggcact gacagtagtc tgagtggata aggatggagt aagagcagcc atcggttctt
     3541 tcggctcatc aggcgttatc tctacaggta ataattcaac gcctgcgtca gaagtggttg
     3601 tcaccggaag acgccgtgat atacgccctt cgttttgcca gagtctgagc catttgaaaa
     3661 taacatcatc attgacgcca ttttctcgtg caatctgggc catacaagca ccgggttgtg
     3721 atgccagttc aaccatacga agtttgaatt cattcgaata ctttttacga ggttcttttc
     3781 gccagtcctg taattccata cttggatgtc cgtctgtgtc agatgggcgt ctaagttacc
     3841 aattcttgtc taatggctac atactgcggt cggtttacgc ttacttttaa cgtaaaaacc
     3901 gtgatggcaa gcctgtgccg tcacggactg agggcaaagg cttcccggaa gttcagccct
     3961 taccgcacac agcctgcctg tgtcagaaaa tctgctggag ctgtcaacga cggatgaaaa
     4021 gtgcctcttc cgcaacctgg gtggagattt tcatgccagt ggactcatta ccctctgcct
     4081 gagtagttca aatcctgctc gaccatacat ctggcgtttc agcatcttca ggcgatttac
     4141 atgaccttcg acaacaccat tactccagcg actactgatt gcctcacata tagctgcagc
     4201 atcagcttcc atccccgccg ccactcgccg aaattctgct gaaccgcttt cgtggactcg
     4261 agtgaaccaa ctacttagct gtgatttatt ttgggttttc agaatacggt agaactcgag
     4321 tgccagttgc tgcgctattt tcagctcagg ttcttttcac acatcagact aataaatcgg
     4381 gaagcataat tttcttcatc cctggttatt ctccagggca tcaaccagcg gcttacccgg
     4441 gccaccattt cccgccatat ccggctggcg ttataattac cactttctcg ttgctctttt
     4501 aaccactccc tccatgggtc cagaagccct cgctttggag gtcgggttga catttcaggg
     4561 aatgttcctg aacgcaccca gcgactgact gtcacacgcg acaggcctgt aatacgggat
     4621 atttccctga aactacatcc cttgttatgc tgggccataa cctctgtcca acgctgatgc
     4681 cgttttttgc gggtttgttg ttttaggcgt tccggacgac ggagcgatgc tgcaggctca
     4741 gacagttctg gctcaggtgg tttctttggt gacaactcgc tggcaacaag acgtatcaga
     4801 ggtatatgtc tgtacatcat tcgttcaagc gcatcgccaa tattttttag caggtggcat
     4861 cgaccacctg tctggcctgt ggtacacctt cacgtgctgc tgtcgcacag accccactgc
     4921 gatcacgcga gacaatctgt atttccggat attttctgaa ccaggtcgcc agcgtacgct
     4981 gatcacggcc gggaagcagg acgaggggac ggtgagtatc aagattgacg attaacgtac
     5041 cgtaacggtg gccccgatgc cacgcccact catcaatacc gacatgaggc gcgcctgact
     5101 gtttcgtctc cggggtattg ataaccctgc gaaggagagt atcagcactg caacggagac
     5161 ccactgccgt tgctgcccgt tttccggcct cacctccggc gattaatccc agttgacgct
     5221 gtaaattttg taacgcctgt gaagactgca gatgtgaacc accgaaggga acaaacgact
     5281 cggcaaaaat ttttcgtgaa caagccgggt tacggctgta cctgtggcgg acggaaaata
     5341 caagccatag cgtctgccct gagcagggta gatgctgtat ccggcgccga cgacaactat
     5401 gaacagagtc gctacgctta aagcattcag gacattgtgc tgttttgcgt tttccgcgga
     5461 gatggagggg tataccgtca gagttaataa tttgtcgact acatcgccat ccgcaaggta
     5521 actgtagaag tgttttaaga gagtgcattg cgttacccat aactaaaaac agcttagatc
     5581 cttgttcacc ataaagtttc atccattttc tccacccagg ttgcggaaga accacttttg
     5641 caccgttcgt gacaggagca ggatttttac gccagtagcc agagccagaa gtgggcgcga
     5701 gacatcacgt acttacgtac ggatgaaggc tggctgtatc tgggagtggt taatgtcgcc
     5761 acgtatgtct gcataagaga cctcggaacg ttatgctacc gcatgtcatt tgcaaaaatg
     5821 acagatagat atacttcaat ttaaacctta acaattagca tgggaatgct gtcaatcctc
     5881 tgtatgcaaa aatggcatct gaatcgctca ttatttagcc ctctgtgtca aagcgtaaag
     5941 tgttcccaga gagcctgtac atagattcgt gtaatttcct gattttgata tgttcatcga
     6001 caggaattta tcccccggaa agattaagaa aacaaaaaac gaacatttat tcaacacatc
     6061 cggaacctca tcgggtatat atcagcgctt atattgctga cattgattga tacagggtat
     6121 cggtgacgtt tttttgctcc atttccctca aaatggacgc aacttcccct ctgcggctct
     6181 cagccgcaat actgcattcg ggccagcggc tcatgcatca taaccagctc tgccagacgg
     6241 taaccccgct tcagccccgt aaaccgcatc tgactttcgc acaggatgca tttcagcggg
     6301 tcaaccttca gtaaccgctg atacatccct ctccacctga tttgcatcgc cgtttttatc
     6361 accgtctctg ttattacgta cactaattct tccagcaacc ggcgtttcgc cggactaagg
     6421 aacccgtaga acctcaccat acggaacccc ttatccgcca catgccagga gaacctttcc
     6481 ataaacgcat caccactcat caataggtat tcttcacgtc gtgtgcggtg actgttgtaa
     6541 cgcagtccga tttcatcctg accggcatag tgctccagac ggctcattgg caccggcggc
     6601 tttttcaggt aagagccaaa gtacaccgcc acatgtgtgg cgttatccat cacctttgat
     6661 acgttgacat tcctgccccg tcggtaatga ctgtccagga aacgattcca ttcccgttta
     6721 ctgcttcctt cagcagccag ctcatccggt atcaatagtt ccgggtattt ccgtgacagt
     6781 aaccgtgtta tccggtatcg ctacatactc atcaccttac gggcgtaaaa atgaaggttt
     6841 ttccaggtgt gatgtgatgt cacaccgccg gcagttgtcg ataaatggat aaatggatat
     6901 gtggatatgt ggatgacact gctggtcccg gccccatgtg tggattaccg tgaatatccc
     6961 cggcttcaca tctgctgcta tgcggctcat ctctgccagt aaccaccggt tgtggaacac
     7021 cagggaccag tactggcagg gaagcgtgaa tacaattgct gccacgggcc gtcggggacc
     7081 agactcagca gatactgtat ccactgtgca cccgctttca ccccgcagtg tgggcaggag
     7141 cgttttttac accgaaaaca gaccttcttt gtattgcaac agtccgggca gtacatgccg
     7201 ccggcgctga taccggcaag aatggtcgta aactcccgct ctgtacagcg ggcgatttcc
     7261 ggatgccctt cgtcatcaac acgtacaaac cagaagacca gctttttgtt tccggcatcc
     7321 acaaagaacg gaatattcag gtctgcgcaa cactcaacag tatcgtcaaa attatcgaag
     7381 cgcagaatct ctacttcttc ttcgtcaaaa aaatcatctt cgtgaagttt tacaacatag
     7441 cggggaagtt tgcttctttg aggtgcgagt tttcgtttac ggggtttagc tgaacgtgcc
     7501 atataactac ctgaaagaca atgacattgt ttgtttttat aacggtaatt tcaggccatg
     7561 acaagccgca gccgctaggc tgcctactcg atcgatagga atttaaatcc caaaaagatt
     7621 aaaaaaacac ccaaaaacgg atgtttattc aacactgcct gcgtgccatg agtgcaccgc
     7681 cgtcaattaa atggatctta tcgattgata ctgcatatca ctgatggttt tttaccccat
     7741 tcccctgaaa atggacgcaa cttctccgat gcggctctca gcc
//
LOCUS       DAZUDJ010000134         7735 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.136, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000134 DAZUDJ010000000
VERSION     DAZUDJ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7735
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.136"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(54..1217)
                     /gene="fadA"
                     /locus_tag="ACHY1N_004753"
     CDS             complement(54..1217)
                     /gene="fadA"
                     /locus_tag="ACHY1N_004753"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003988 - acetyl-CoA C-acyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HFS4046912.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPA
                     LEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGI
                     SREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LATLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSVSDIGVFEMNEAFAAQILPCIKDLGLMEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFERV"
     gene            complement(1227..3416)
                     /gene="fadB"
                     /locus_tag="ACHY1N_004754"
     CDS             complement(1227..3416)
                     /gene="fadB"
                     /locus_tag="ACHY1N_004754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0036125 - fatty acid beta-oxidation
                     multienzyme complex [Evidence IEA];
                     GO_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0004165 - delta(3)-delta(2)-enoyl-CoA
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0004300 - enoyl-CoA hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008692 - 3-hydroxybutyryl-CoA epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009062 - fatty acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HFS4046913.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIG
                     VLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTIAAANGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGA
                     DSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAVLRQAINGDLDWKAKRQPK
                     LEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDVVVEAVVENPKVKKAVLAETEQKVRPDTVLASNTSTIPISELANALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQK
                     DYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSE
                     EEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAK
                     YLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA"
     gene            3606..4937
                     /gene="pepQ"
                     /locus_tag="ACHY1N_004755"
     CDS             3606..4937
                     /gene="pepQ"
                     /locus_tag="ACHY1N_004755"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HFS4046914.1"
                     /translation="MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTE
                     DVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRS
                     FKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIES
                     LLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA"
     gene            4937..5551
                     /locus_tag="ACHY1N_004756"
     CDS             4937..5551
                     /locus_tag="ACHY1N_004756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HFS4046915.1"
                     /translation="MESWLIPAAPVTVVEEIKKSRFITMLAHTDGVEAAKAFVESVRA
                     EHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYSQLTGIEALLGQCDG
                     KIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE"
     gene            5590..7041
                     /gene="trkH"
                     /locus_tag="ACHY1N_004757"
     CDS             5590..7041
                     /gene="trkH"
                     /locus_tag="ACHY1N_004757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HFS4046916.1"
                     /translation="MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFF
                     VALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATI
                     AIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQFTLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            7053..7598
                     /gene="hemG"
                     /locus_tag="ACHY1N_004758"
     CDS             7053..7598
                     /gene="hemG"
                     /locus_tag="ACHY1N_004758"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HFS4046917.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKELGIQTDVANVHRIEEPQ
                     WENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTN
                     SYARKFLMNSQWRPDHCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTD
                     WEQVANFAREIAHLTDKPTLK"
BASE COUNT         1713 a         2094 c         2106 g         1822 t
ORIGIN      
        1 tggtgccgga tcggtagacc ggataaggcg ttcacgccgc atccggcaag tggttaaacc
       61 cgctcaaaca ccgtcgcaat accctgaccc agaccgatac acatcgtcgc cagaccaaac
      121 tggacgtctt tgcgctccat cagatttagc agcgtggtgc tgatacgcgc accggaacag
      181 cccagcggat gacccagcgc gatcgcgcca ccgttgaggt tgatcttctc gtcaatctgc
      241 tccattagcc ccagatcttt aatacatggc aggatctgcg cggcaaaggc ttcattcatt
      301 tcaaacacgc cgatatcact gacagaaagc cccgcttttt tcagcgccag cttcgaggcc
      361 ggaaccgggc cgtaacccat aatcgatggg tcacaaccaa cgaccgccat cgaacgcacg
      421 cgggcgcgcg gcttaagacc taattcatgg gcgcggcttt cactcatcac cagcatggca
      481 gctgcgccat cggaaagcgc agaagatgta cccgccgtta ccgtaccgct tactggatca
      541 aacgccggac gcagcgtggc gagggcttcc acggtggttt ccgggcgaat cacttcgtcg
      601 taattaaact gcttcaggac gccgtcggca tcgtgaccac cggtcgggat aatttcattt
      661 ttaaatgcac ccgactgcgt ggcggcccag gcgcgggcgt gtgaccgcgc ggcaaaggca
      721 tcctgcattt cacggctgat accgtgcata cgcgccagca tttctgccgt taagcccatc
      781 atgcccgccg ctttggcgac attgcggctc aggccggggt gaaaatcgac gccgtggctc
      841 attggcacat ggcccatatg ctccacgccg ccgacaagac atgcctgcgc atcgccagtc
      901 atgatcattc gtgctgcgtc atgcaatgcc tgcatggatg aaccacacaa gcgattgacg
      961 gtcaccgccg ggacagagtg tggtacttct gccagcagcg ccgcgttacg ggcgatatta
     1021 aaaccctgct ccagcgtctg ctgcacacaa ccccagtaaa tatcgtcgag ggccgccgct
     1081 tccagcgccg ggttacgcgc cagcaggcta cgcattaaat gagcggagag atcttctgca
     1141 cgcacgttac gaaaagcacc gcccttcgaa cggcccatcg gggtgcgaat tgcatcgaca
     1201 atgacaacct gttccattgt gactccttaa gccgttttca ggtcgccaac cggacgggct
     1261 ggctcaaccg gaggatagta cggttcgtta tgacgcgctt tattacgcag accttccggc
     1321 acttcataca gcgggccgag gtgctgatat tgctgtgcca tatcgaggta ttttgcgcta
     1381 ccgagggtgt ccagccagcg gaacgcgccg ccgtggaacg gagggaagcc caggccgtag
     1441 accagcgcca tatccgcttc cgccggagtg gcgataatgc cttcctccag acagcgcacc
     1501 acttcgttga ccatcgggat catcatgcgg gcgataatct cttcttcgct gaaatcgcgc
     1561 ttcggctggc tcacttctgc cagcaggtct tcaacggcgg cgtcttcttc tttcttcggc
     1621 ttacctttgc tgtcttcttt ataacgccag aaaccgaggc cgttcttctg accaaagcgg
     1681 ttggcatcaa acagcgcgtc gatggcatcg cggtaatctt tctgcatccg ctgcgggaag
     1741 cctgctgcca tgacagcctg agcgtgatgc gcggtatcaa tgcccacgac atccagcaga
     1801 tatgccggac ccataggcca gccaaactgt ttttccatca ctttgtcgat cttgcggaaa
     1861 tccgcgccgt cgcgcagcag ctggctgaaa ccggcgaaat acgggaacag cacgcggtta
     1921 acaaagaagc cggggcagtc gttaaccaca atcggcgtct tgcccatctt gctcgcccag
     1981 gcgacaactt tcgcgatggt ttcgtcggag cttttctcgc cgcgaataat ttctaccaac
     2041 ggcatccggt gtaccgggtt aaaaaagtgc attccgcaga agttttccgg gcgttccagc
     2101 gcgttggcca gttcgctgat aggaatggtt gaagtgttag acgccagcac ggtatccggg
     2161 cgtacttttt gttcggtttc tgccagtacg gcttttttca ctttcgggtt ttcgacaacc
     2221 gcttctacca caacatccac gcggtcaaac ccggcgtagt cgagcgttgg gtggattgtg
     2281 gagatcacgc cagccagttt cagaccatcg atcttgccgc gctcaagctg cttgttcagc
     2341 agtttcgcgg cttcggtcat gccgagggtt aacgacttgt cgttgatatc tttcatgaca
     2401 accggcacgc ctttccacgc agactggtaa gcgatgccgc cgcccataat gcctgcaccc
     2461 agcaccgcgg cctgtttcgg ggtttcaacg tctttggtga gtttcttcgc tttgcctttt
     2521 acatattgat cgttaaggaa aatgccgacc agtgcgcggg cttcgttggt atgcgccagc
     2581 gggacaaaac ttttgttttc caggtttaag gcttcttcac gaccaaaacg ggccgcagct
     2641 tcaatggttt ttactgcggt gatgggggcc ggataatgtt tccccgctgt ttgtgcgacc
     2701 atccctttag cgatggtgaa gctcatggtg gcttcaatct tgctcagttt tagtggttcc
     2761 agcttcggct gacgttttgc tttccagtcg aggtcgccgt taatggcctg gcgtaaaacc
     2821 gcctttgcgc cttcaaccag tttttctgct ttgactacgc catccaccag accgattttc
     2881 agcgcctgat ccgcgccgac atctttaccg gcggcaatga tttccagcgc actgtcagcg
     2941 cccagcatac gtggcatacg tacagaaccg ccaaagcccg gcatgatgcc cagtttggtt
     3001 tccggcagac cgatgcgcag atccggcgtc gccagacgat aatcggtcgc cagcacgcat
     3061 tcgcagccac cgcccagcgc atagccgttg gcggcagcaa tggtcggcac cggcagatct
     3121 tccaggcgat taaacacgct attggcaaag tgcagccact gacttaactg ttcttcagga
     3181 acgaggaaca gggacaaaaa ttcggtgata tcagcaccga cgataaaggc tgctttgttc
     3241 gaacgcagca gcagcccttt tagatctgat tgctgttcca gcacgccgat ggcctcgccg
     3301 aggctggcga cggtcgcagt gtcgagttta ttaactgaac ctggggcatc aaataccagt
     3361 tcggcaatgc catcttccag ccagtcaagg tacagggtgt cgcctttgta aagcatgtca
     3421 gtctcctgaa tccgcaaggt gatctggtcg taccagatga gtcgaagtgt gtattttgtg
     3481 ttaaaaatat gcaaataaaa gattaaagaa atgccgatct gatcacgctc ggcagaaatc
     3541 acgctctgga tgaacgatgt gctaagatgc ggagacttaa ggtcaaaaaa acagaagggt
     3601 aaaaaatgga atcactggcc tcactctata aaaatcatat agctacctta caggaacgga
     3661 ctcgcgatgc gctggcgcgc ttcaagctgg atgcgttact tattcactcc ggcgaactgt
     3721 tcaacgtttt tctcgacgat catccctatc cgtttaaagt gaacccgcaa ttcaaagcgt
     3781 gggtgccggt aactcaggtg ccaaactgct ggctgctggt ggatggcgtg aacaagccga
     3841 aactgtggtt ctatctgccg gttgattact ggcacaacgt cgaaccgctg ccgacctctt
     3901 tctggactga agacgtggaa gtgatcgcgc tgccgaaagc cgatggcatt ggtagcctgc
     3961 tgcctgctgc gcgcgggaat atcggttata tcggtccggt gccggaacgt gcgctgcaac
     4021 tgggtattga ggccagcaat atcaacccga aaggggtgat cgactacctg cattactacc
     4081 gctccttcaa aaccgagtac gaactggcct gtatgcgtga agcgcagaaa atggcggtca
     4141 acggtcatcg cgcggcagaa gaagcgttcc gttctggcat gagcgagttc gatatcaaca
     4201 ttgcctatct gaccgcgacc ggtcatcgtg ataccgacgt accttacagc aacattgtgg
     4261 cgctcaacga acacgctgcg gtgttgcatt acaccaaact ggaccaccag gcaccggaag
     4321 agatgcgcag cttcctgctg gatgccgggg ccgaatataa cggctatgcg gctgacctga
     4381 cccgtacctg gtcggcaaaa agtgacaacg actacgcaca gctggtgaaa gacgtaaatg
     4441 atgaacaact ggcgctgatc gctaccatga aagcaggcgt cagctatgtg gattaccaca
     4501 tccagttcca tcagcgcatc gccaaactgc tgcgtaaaca tcaaatcatc accgatatga
     4561 gtgaagaagc gatggtcgaa aacgatctca ccggaccgtt tatgccgcac ggtattggcc
     4621 atccgctggg cctgcaggtg catgacgtag ccggttttat gcaggatgat agcggtacgc
     4681 acctcgcggc accggcaaaa tatccgtacc tgcgctgcac ccgtattctc cagccgggca
     4741 tggtgttaac catcgaaccg ggtatctact tcattgaatc gctgctggca ccgtggcgtg
     4801 aagggcagtt cagcaagcac ttcaactggc agaaaattga agcactgaaa ccgttcggcg
     4861 gcattcgtat cgaagacaac gtggtgatcc acgaaaacaa cgtggaaaac atgacccggg
     4921 atctgaaact ggcgtgatgg aaagctggtt aattcctgcg gcaccggtca cggtcgttga
     4981 agagatcaaa aaaagccgct tcataacgat gttggcgcat accgatggcg ttgaggcggc
     5041 gaaagcgttt gttgaatcgg tgcgggcaga acaccccgat gcccgccacc attgcgtggc
     5101 gtgggtggcg ggtgcgccgg atgattctca acagctgggt ttctctgacg acggggagcc
     5161 ggcgggaacg gcaggtaaac cgatgctcgc ccagctaatg ggcagcggcg tcggggaaat
     5221 taccgctgtg gtagtgcgct actacggcgg catattgctt ggcaccggtg ggttagtgaa
     5281 agcgtatggc ggcggcgtga atcaggcgct gcgccagcta acgacccaac gcaagacgcc
     5341 attaaccgaa tatactttgc aatgtgaata tagtcagtta accggcattg aagcgttgct
     5401 ggggcagtgt gacggcaaaa ttatcaacag tgattatcag gcattcgttc tgctgcgggt
     5461 ggcgcttccg gcggcgaaag tggctgaatt ttccgcaaag ctggcggatt ttagccgtgg
     5521 ttcattgcaa ttgttagcga ttgaagaata atccccactt cgttttgcag aactaaggaa
     5581 gcggcagaga tgcattttcg cgccattacc cgaatcgttg gactactggt catcttattt
     5641 tcagggacca tgattatccc tgggctggta gcactcatct accgggatgg agcgggccgc
     5701 gcttttaccc agaccttttt tgtcgccctc gccattggct ctatgctgtg gtggccgaac
     5761 cgcaaagaga agggcgaact gaaatcccgt gaggggtttc tgatagtggt gctgttttgg
     5821 accgtgctgg gtagcgtcgg tgcgctccct tttatcttct cggaaagccc gaacctcacg
     5881 attaccgatg cgttttttga atctttctct ggcctgacca ccaccggggc cactacgctg
     5941 gtggggctgg attcgctccc tcatgccatc ctcttttatc gccagatgct gcaatggttt
     6001 ggcgggatgg ggatcatcgt gttagcggtt gcgatactgc ctatcctcgg cgtgggtggg
     6061 atgcagctct atcgcgcaga aatgcccggc ccgctgaaag ataacaaaat gcgcccgcga
     6121 attgcggaaa cggcgaaaac cctgtggttg atttatgtct tgctgaccgt cgcctgtgcg
     6181 ctggcgttgt ggtttgccgg aatggatgcc tttgatgcca tcggccatag ctttgcgact
     6241 atcgctattg gcggcttctc gacacatgat gccagtatcg gttatttcga cagcccgact
     6301 attaacacta tcattgctat cttcctgctg atctccggct gtaactacgg tctgcacttt
     6361 tcactgttaa gtgggcgtag tctgaaggtt tattggcgcg atccggaatt tcgcatgttt
     6421 atcggcgtac agtttacgct ggtggttatt tgtacactcg tactgtggtt tcataatgtc
     6481 tacagttcgg cgctgatgac aattaaccag gcgtttttcc aggtggtatc gatggcgaca
     6541 accgccgggt ttacgactga cagcattgcc cgctggccgc tctttttgcc ggtactgctt
     6601 ttatgttcag cttttatcgg cggttgcgcc gggtcaacgg gcggtggcct gaaagtgatc
     6661 cgcatcctgc tgctgtttaa gcaggggaac cgtgagctga aacgactggt gcatccgaac
     6721 gccgtctata gcattaagct ggggaatcgc gcactgccgg aacgtatcct cgaagccgtt
     6781 tggggatttt tctccgccta tgcattggtg tttattgtca gtatgctggc gattatcgcc
     6841 acgggcgtgg atgacttttc tgcctttgcc tcagttgttg cgacattgaa taacctgggg
     6901 ccagggcttg gcgtggttgc tgataacttt accagtatga acccggtggc taaatggatc
     6961 ctgattgcca acatgctgtt tggtcgtctc gaggtcttta cattgctggt gctctttacc
     7021 ccgactttct ggcgtgaatg atggagtaat acgtgaaaac attaattctt ttctcaacaa
     7081 gggacggaca aacgcgcgag attgcctcct acctggcttc ggaactgaaa gaactgggga
     7141 tccagacgga tgtcgccaat gtgcaccgca ttgaagaacc acaatgggaa aattatgacc
     7201 gtgtggtcat tggtgcttct attcgctatg gtcactacca ctctgcgttc caggaatttg
     7261 tcaaaaaaca tgcgacgcga ctgaattcga tgccgagcgc cttttattcc gtaaacctgg
     7321 tggcgcgcaa accggagaag cgtactccac agaccaacag ctacgcgcgg aagtttctga
     7381 tgaactcgca atggcgtccc gatcactgcg cggtcattgc cggggcgctg cgttacccac
     7441 gttatcgctg gtacgatcgt tttatgatca agctaattat gaagatgtca ggcggtgaaa
     7501 cggatacgcg caaagaagtt gtctataccg attgggagca ggtggcgaat ttcgcccgag
     7561 aaatcgccca tttaaccgac aaaccgacgc tgaaataagc ataaagaata aaaaatgcgc
     7621 ggtcagaaaa ttattttaaa tttcctcttg tcaggccgga ataactccct ataatgcgcc
     7681 accactgaca cggaacaacg gcaaacacgc cgccgggtca gcggggttct cctga
//
LOCUS       DAZUDJ010000135         7661 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.137, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000135 DAZUDJ010000000
VERSION     DAZUDJ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7661
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.137"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            17..541
                     /locus_tag="ACHY1N_004759"
     CDS             17..541
                     /locus_tag="ACHY1N_004759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long polar fimbria major subunit LpfA"
                     /protein_id="HFS4046918.1"
                     /translation="MKKVLFALSALALTSTSVFAADAGDGTVKFTGEIVDAACVVSPD
                     TQKQEVVLGQVNKSVFTAMGDKSTATPFKIKLENCDISTFKNVEISFNGVGDADNSKL
                     VSVSTEPGAATGVGIGIYDNTNTLVDLNTGKSATVLKEGQTVLYFTANYVSTKDAVTT
                     GYGNAEVDFNLTYN"
     gene            625..1311
                     /gene="lpfB"
                     /locus_tag="ACHY1N_004760"
     CDS             625..1311
                     /gene="lpfB"
                     /locus_tag="ACHY1N_004760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long polar fimbrial biogenesis chaperone LpfB"
                     /protein_id="HFS4046919.1"
                     /translation="MKRISFAVLALLMTAQQCFAGGVALSTTRVIYDGGKKEASLTVE
                     NHNKNEEFLIQSWIDDVNSNKKTPFIITPPLFKLDPDKNNVLRIVNIEDTLPKDRESV
                     YWINVKAIPAKSAENENKNVLQIAVRTRLKLFYRPKGLPGSNLEAMKQLRFQRQNNQI
                     VVNNDSAYNLTFNQFSINGQKIERAGMVLAKGKLNINLPAGTGNAHEVKYSIINDFGV
                     TGEMLTKPIN"
     gene            1335..3866
                     /gene="lpfC"
                     /locus_tag="ACHY1N_004761"
     CDS             1335..3866
                     /gene="lpfC"
                     /locus_tag="ACHY1N_004761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001759518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane usher protein LpfC"
                     /protein_id="HFS4046920.1"
                     /translation="MHWMHLPLYHYRAHFSFSLLALTIASSLPAYGGKFNPKFLENVQ
                     GIDQHIDLSVYDSPVGQQIPGKYRVSVFVNEEKMASRTLDFSTASEAKRKASGESLMP
                     CLSRVQLEEMGVRVDSFPALKMSPPEACVAFDEIIPQATSRFDFNTQTLHLSFPQAAM
                     MMTARGTVDPSRWDEGIPALLLDYSFSGSNGRNEGTGSSSDSTSDSYYLNLRSGLNVG
                     PWRLRNNSIWNRTDGKNQWDNVGTSLNRAIIPLKSQITLGDTATPGEIFDSVQMRGAL
                     LASDDEMLPDSQRGFAPVVRGIAKSNAEVSIEQNGYVIYRTFVQPGAFEINDLYATSG
                     SGDLTVIIKEADGSEQRFIQPFSAVAIFQREGYLKYSLAAGEYRAGNYDSDKPHFGQF
                     TAMYGLPWGMTAYGGALLSADYNALALGLGKNFGTIGAVSVDVTQAKSQLRNNEKEEG
                     QSYRFLYSKSFEGGTDLRLLGYKYSTSGYYTFQEATDVRSDADSDYRRYHKRSQIQGN
                     ITQQLGDYGSVYFNMTQQDYWNVDGKENSLSAGYHGHIGRVNYSVAYTWTRSPEWEED
                     DRLWSFSVSIPLGGAWSSYRMTTDQNGKTSQQASVSGTLLEDRNLSYNVQQGYTSNGV
                     GYSGSVNMGYMGGSGNIDVGYNYSKDNQQVNYGVRGGVIVHSEGITLSQPLGESLAIV
                     SAPGARGGHVVNSSGVEVDWMGNAVVPYLTPYRETIVELRSDTLGQNVELQEAFQKVV
                     PTRGAVVRSRFDTRVGYRVLMSLKQANGNAVPFGATAALIDESKPASSIVGEEGQLYI
                     SGMPEEGELQVSWGNEQAQRCRVPFRLPENKDNAAIVMVNAVCEK"
     gene            3877..4932
                     /gene="lpfD"
                     /locus_tag="ACHY1N_004762"
     CDS             3877..4932
                     /gene="lpfD"
                     /locus_tag="ACHY1N_004762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long polar fimbrial protein LpfD"
                     /protein_id="HFS4046921.1"
                     /translation="MKIKNLLAGMVLLGTSTFAGNIWAADWGPCQTSNGVAHEYSFDF
                     VQTIQVPSENKAGKILTQPFALGTKYSAYCECPDPIPDNGVVTYFKGVTLLPEPGTVD
                     GYYKFNNYIDILTKIYVYTQLDIPVPFTDRSNGTAQKECTPYTANNWGTGGKGSISIY
                     ISHPFVGQMIIPKTRVASLFGTKKKGVYNDSQPMANVSISGSITVTQGCELAAGTVLD
                     IPFGEYQAHDFKGRAGQPPQNVQKVQKELSFDCNNISDGVKIYLSIDATPNTAYPSAI
                     DLGNADVGAVIEDGKGNILKPNDSNSLLEMNPGSLYEDVKRKATTTITAYPVSTTGKL
                     PAAGDYSGIATIHVELE"
     gene            4938..5462
                     /gene="lpfE"
                     /locus_tag="ACHY1N_004763"
     CDS             4938..5462
                     /gene="lpfE"
                     /locus_tag="ACHY1N_004763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long polar fimbrial protein LpfE"
                     /protein_id="HFS4046922.1"
                     /translation="MKRTILALCLLPLSFSSFAATTDLGPKGTLKFTLKISQGACELV
                     KDSVEVDMGTAVLKKPVRIGTEINPTPFSIGLKNCSEVVRAYVTMDGTPNADDSNLFA
                     LDAGGATGVGLKIKTAAGVQQFPENTTPTPVEFAINGDGAHQLNYIASYVPIRADATI
                     GRADATVDFTVQYE"
     gene            5715..7406
                     /gene="eptB"
                     /locus_tag="ACHY1N_004764"
     CDS             5715..7406
                     /gene="eptB"
                     /locus_tag="ACHY1N_004764"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HFS4046923.1"
                     /translation="MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWK
                     GVSAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRS
                     LAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAW
                     ARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     AQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDL
                     YAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLI
                     ILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVID
                     QVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPANAQ
                     AFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQTKVAAAN"
     gene            7498..7574
                     /locus_tag="ACHY1N_004765"
     tRNA            7498..7574
                     /locus_tag="ACHY1N_004765"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7532..7534,aa:Pro,seq:cgg)
BASE COUNT         1995 a         1758 c         1933 g         1975 t
ORIGIN      
        1 ataaatggag ttataaatga aaaaggttct gtttgcctta tctgcgcttg cgctgacctc
       61 tacttccgta ttcgcagctg atgcgggcga cggtactgtt aaattcaccg gtgagattgt
      121 tgacgccgct tgtgttgtgt ctccagacac tcaaaaacaa gaagttgttc tgggtcaggt
      181 gaacaagtct gtatttactg ctatgggtga taaatccaca gcaacgccgt tcaaaatcaa
      241 actggaaaac tgcgatatct ccactttcaa aaatgtggaa atcagcttta acggcgttgg
      301 cgatgcagac aacagcaaac tggtttctgt aagcactgaa ccaggtgccg caactggcgt
      361 aggtatcggt atttatgata acaccaatac cctggttgac ctgaatactg gtaaatctgc
      421 tactgtcctg aaagaaggtc agaccgttct gtatttcacc gctaactatg tctctaccaa
      481 agatgcagta accacgggtt acggtaacgc tgaagtcgac ttcaacctga cttacaacta
      541 atcgatcctg acggaacgat catctctcaa tggcaacaga gactgtgttg ccattattca
      601 caccaatgac tcagggaccg aatcatgaaa cgtattagct ttgctgtgct ggcactttta
      661 atgaccgcac aacagtgttt tgctggtggc gtagccttaa gcacgacgcg tgttatttat
      721 gatggcggca agaaagaagc gtcgctgacc gttgaaaacc ataataaaaa tgaagagttt
      781 ttgatccagt catggattga tgatgtgaat agcaataaaa aaacaccgtt tattattaca
      841 ccgccattat tcaaacttga tcctgataaa aataacgtct tacgtatcgt caatattgaa
      901 gataccttac ctaaagatcg tgaatccgtt tactggatta atgtaaaggc cattcctgcg
      961 aaaagtgctg aaaatgaaaa taaaaacgtc ttacagatag ccgttcgcac ccgtttgaag
     1021 ttgttctatc gtccaaaagg tttgccggga agcaacctcg aggccatgaa acagttacgt
     1081 ttccagcgtc aaaataacca aattgtggtt aataacgact ccgcttataa cctgaccttt
     1141 aatcagtttt ccattaatgg acaaaagatt gaacgggcgg gaatggttct cgcgaaagga
     1201 aagttaaaca ttaaccttcc agccggtaca ggcaacgcgc acgaagtgaa atacagcatt
     1261 attaatgatt tcggtgttac tggcgaaatg ctgacgaagc cgattaactg atccttttac
     1321 aaggcgcttt tactatgcat tggatgcatt tacctctcta tcactacaga gcgcattttt
     1381 ccttctctct gctggcatta acgattgcca gctcgttacc tgcgtatggc ggaaaattta
     1441 accctaaatt tctcgaaaac gttcagggta tcgatcaaca catcgacttg tcggtatacg
     1501 actcacctgt cggccagcaa atccccggta aataccgggt ttcggtgttt gtaaacgaag
     1561 aaaaaatggc ttcccggacg ctggatttta gtaccgccag cgaagcgaaa cgcaaagcca
     1621 gcggtgagtc gcttatgcct tgccttagcc gggtgcaact ggaagaaatg ggcgtgcgcg
     1681 ttgacagctt tccggcgctg aagatgtcac caccagaagc ctgcgtagcg tttgatgaaa
     1741 tcattcccca ggccaccagc cgctttgatt ttaatactca gacgctgcat ctttcctttc
     1801 cacaggcggc aatgatgatg accgctcgcg gcacggttga tccttctcgc tgggacgaag
     1861 gaatacctgc gctgttgctg gattacagct ttagtggcag caatggacgc aatgaaggta
     1921 caggttcatc ttcagattcg accagtgaca gttattacct gaacctgcgc agcggtttga
     1981 acgttggtcc gtggcgttta cgtaataaca gtatctggaa ccgtaccgat ggcaaaaacc
     2041 aatgggataa cgttggtaca tcgttaaacc gggcaattat tccacttaaa tcacagataa
     2101 ctctgggtga taccgccacg cctggcgaga tttttgatag cgtacaaatg cgtggggcgt
     2161 tactggcatc cgacgatgaa atgttgccgg acagccagcg tggctttgct ccggtagtgc
     2221 gcggcatcgc caaaagcaac gctgaagtga gtatcgaaca gaacggctat gtcatttatc
     2281 gcacttttgt tcagccgggt gcatttgaga ttaacgatct ctacgcaacc tccggcagcg
     2341 gcgacctgac ggtgatcatt aaagaagccg acggaagtga acaacgtttt atccagccgt
     2401 tttcggcggt ggcgattttc cagcgtgaag ggtatctgaa atacagtctg gctgccggtg
     2461 aatatcgtgc tggtaattac gacagcgata aaccacattt cgggcagttt accgccatgt
     2521 acggcttgcc gtggggtatg accgcctacg gtggtgcatt gttgtcggca gattacaacg
     2581 ctttagctct gggcctgggg aaaaacttcg gtaccattgg cgcagtatcg gtggatgtca
     2641 ctcaggcgaa aagtcagtta cgcaacaatg aaaaagagga aggccagtct tatcgcttcc
     2701 tctattcgaa aagttttgag ggtggcactg acctgcgtct gttgggctac aaatactcaa
     2761 ccagcggcta ctacaccttc caggaagcaa ctgatgttcg cagtgacgcc gacagtgatt
     2821 accgccgtta tcacaagcgc agccagatac agggcaatat tacccagcaa ctgggagact
     2881 acggctcggt ttatttcaat atgacgcagc aggattactg gaacgttgac ggtaaggaaa
     2941 actccttaag cgccggttat cacggtcaca ttggtcgggt gaattacagc gtggcctata
     3001 cctggacgag aagtccggaa tgggaagaag acgatcgctt gtggtcattc agtgtttcca
     3061 tccctctggg gggcgcgtgg agcagttatc gcatgactac cgaccagaat ggcaagacgt
     3121 cgcaacaggc ctctgttagc ggcacgttac tggaagatcg taacctgagc tataacgttc
     3181 agcagggtta caccagtaat ggcgtaggct acagtggcag cgtcaacatg gggtatatgg
     3241 gtggctctgg taacattgac gtaggctata actattctaa agataaccaa caggttaact
     3301 atggcgtgcg cggcggtgtc atcgttcaca gtgaaggtat aacgctttcg cagcctttag
     3361 gcgaaagtct ggcgattgtt tctgcaccgg gcgcgcgtgg tggacatgtg gttaacagca
     3421 gcggcgtaga agttgactgg atgggcaacg ccgtggtgcc ttatctcaca ccatatcgtg
     3481 aaaccattgt ggaattgcgt agcgacacgt tggggcaaaa cgttgaacta caggaagcgt
     3541 tccagaaagt cgtgcctact cgtggtgcag ttgtgcgttc ccgctttgat acccgcgtcg
     3601 gttaccgtgt gctgatgagc ttaaaacagg cgaatggcaa cgcagtaccg tttggtgcaa
     3661 ccgcagcgtt aattgatgag agcaaacctg ccagcagcat tgtgggtgaa gaaggacagc
     3721 tttatatcag cgggatgcca gaagagggcg aattgcaggt gagctggggg aacgagcagg
     3781 cgcaacgttg ccgtgtgcca ttccgcttgc cagagaacaa ggacaatgcg gctatcgtga
     3841 tggttaatgc ggtatgcgag aaataaggat atttagatga aaattaaaaa tttgttggca
     3901 ggtatggtgc tgttagggac gagcactttt gctggaaata tatgggctgc ggattgggga
     3961 ccatgtcaga catcaaatgg ggtggcccat gagtatagtt ttgatttcgt acagactatc
     4021 caggtacctt cagaaaataa ggctgggaaa atattaactc agccctttgc tttaggtaca
     4081 aaatattccg cttattgtga atgcccggat cccattccag ataatggagt tgtgacttat
     4141 tttaaaggtg taacgcttct gcctgagcct ggaactgtag atgggtacta taaattcaat
     4201 aattacattg atattctcac caaaatatat gtctacacac aattagatat cccggtgcct
     4261 tttaccgatc gaagcaatgg cacggcacag aaagaatgta cgccctatac tgctaacaat
     4321 tgggggacag gtggtaaagg aagtatcagt atttatattt cacatccttt tgttgggcaa
     4381 atgattattc ctaaaacacg agttgcgtcc ctctttggga caaaaaagaa aggtgtttac
     4441 aatgatagtc agcccatggc caatgtcagt atttccggga gtattacagt tactcaaggc
     4501 tgtgaacttg ccgctggcac cgtactggat attccattcg gagaatatca ggcccatgat
     4561 tttaaagggc gtgccggaca accaccacaa aatgttcaga aggtacaaaa agaattaagc
     4621 tttgactgca ataatatttc agatggcgtc aaaatttatc tcagtattga tgcaacacca
     4681 aatactgcct atcccagcgc aattgattta ggcaacgccg atgttggtgc agtcattgag
     4741 gacggtaaag gtaatattct taagccgaat gacagtaata gcttattaga aatgaaccca
     4801 ggctcgctgt atgaagatgt caaacgcaaa gcgacaacca caattaccgc ttatcccgtt
     4861 agcactaccg gaaaattacc cgctgccggg gattatagcg gtattgctac catacatgtc
     4921 gaactggagt aacagtcatg aagcgaacaa tacttgcgtt atgcctgctg cctctttcct
     4981 tttcgtcatt cgcggcaacc acggatttag ggccgaaagg aacattgaaa ttcaccctta
     5041 aaatcagcca gggtgcttgc gaactggtga aagacagcgt tgaggttgac atgggcaccg
     5101 cggttctcaa aaagccggta agaatcggaa cggaaattaa tcccactcct ttttccatcg
     5161 gcctgaaaaa ctgtagcgaa gtggtcagag cctacgtgac tatggacggt acacccaatg
     5221 cagacgactc aaatcttttt gcgctggatg cgggtggcgc tacaggcgtt gggctgaaaa
     5281 tcaaaaccgc tgctggagta caacagttcc cggaaaatac aacgccgaca ccggttgagt
     5341 ttgcaattaa cggtgatggc gcacatcaac tgaactatat cgccagctac gtgcctattc
     5401 gcgccgatgc aactattggt cgcgcagatg caacggtcga ctttactgta cagtacgaat
     5461 aatttcacat cttaagggcc agttaactgg ccctttttac tgctttttgt aacgctaaag
     5521 tctcttttca aacttgcatt tttgtaaatt tgtgcttcat gcacactctt tccccacact
     5581 ttttcgcttt gctgtggtct acttattcgc gcgtgtagat tttacttatc tgactacctc
     5641 cgcacttttc ccctgccggg cctgaaaagc cgctaagcag ggtgttatca cctgtttgtc
     5701 cagggtttgt ttgcatgaga tacatcaaat cgattacaca gcagaagctg agctttttgc
     5761 ttgcaatcta tattggcctt tttatgaatg gcgcggtttt ttatcgccgc ttcggcagct
     5821 atgcgcacga ttttaccgtc tggaaaggcg tttctgctgt tgttgaactg gccgccaccg
     5881 tactggtgac cttcttttta ctacgtcttc tatcgctgtt tggccgccgc agctggcgta
     5941 ttctggcgtc gctggtggtg ctcttttccg caggtgccag ctattacatg accttcctta
     6001 atgtggtcat tggttatggc atcatcgctt ccgtcatgac caccgatatc gacctgtcaa
     6061 aagaagttgt tggtctgaac tttattctct ggttaatcgc cgttagtgca ttgcctctta
     6121 tccttatctg gaataaccgc tgtcgctaca ccttgctccg acaactgcga accccagggc
     6181 agcgtattcg cagcctggcg gtcgtcgtac tggcgggtat tatggtttgg gcaccgattc
     6241 gtttgctgga tatccagcag aagaaagtgg agagggcgac cggcgttgat ttgccgagtt
     6301 atggcggtgt cgtagcgaac tcttatctgc catcaaactg gctttctgcg ttggggctgt
     6361 atgcctgggc gcgggtcgat gaatcttccg ataataattc attgcttaat ccggcgaaga
     6421 aattcactta tcaggcaccg caaaacgttg atgacactta tgtcgtgttt atcatcggtg
     6481 aaaccacgcg ttgggaccat atgggcattt tcggctatga gcgtaatacc acgccgaaac
     6541 tggcccagga gaaaaatctg gcggcgttcc gtggttactc ctgtgatacc gcaaccaaac
     6601 tctcactgcg ttgcatgttt gtacgtcagg ggggcgcgga agataatccg cagcgcacat
     6661 taaaagaaca gaacattttc gcggttctga agcagttagg attcagttct gacctctacg
     6721 ctatgcagag cgaaatgtgg ttctacagca acacgatggc ggacaacatt gcttatcgtg
     6781 agcagattgg tgcggagcca cgtaatcgtg gcaagccggt agatgatatg ttgctggtag
     6841 acgaaatgca gcaatcgcta gggcgcaacc cggatggtaa gcatctgatc attctgcata
     6901 ccaaaggttc gcattttaac tacacccagc gttatccgcg tagcttcgcg cagtggaagc
     6961 cggaatgtat tggtgttgat agcggctgta ccaaagcgca gatgatcaac tcctatgaca
     7021 actcggtgac ctatgtggat cactttatct ccagcgtgat tgatcaggtt cgcgataaga
     7081 aagcgattgt gttctacgca gctgaccacg gtgagtcaat taatgaacgc gagcacctgc
     7141 acggcacgcc gcgtgaactg gcaccgccgg agcagttccg cgtaccgatg atggtctgga
     7201 tgtcagataa atatctggaa aatccggcca atgctcaggc atttgcgcag ctgaaaaaag
     7261 aagccgacat gaaagtgcca cgccgtcatg tagagctgta cgacaccatc atgggttgtc
     7321 ttggctatac ttcaccggat ggtggaatta acgaaaacaa caactggtgt cacatcccgc
     7381 agacaaaagt ggcagcggct aactaagcgg cctgctgact ttctcgccga tcaaaaggca
     7441 ttttgctatt aagggattga cgagggcgta tctgcgcagt aagatgcgcc ccgcattcgg
     7501 tgattggcgc agcctggtag cgcacttcgt tcgggacgaa ggggtcggag gttcgaatcc
     7561 tctatcaccg accaaattcg aaaagcctgc tcagcgagca ggcttttttg catttgtagc
     7621 tcatgaggat gagaacctcc gggggcgggg aggttcgact c
//
LOCUS       DAZUDJ010000136         7582 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.138, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000136 DAZUDJ010000000
VERSION     DAZUDJ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7582
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.138"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(179..255)
                     /locus_tag="ACHY1N_004766"
     tRNA            complement(179..255)
                     /locus_tag="ACHY1N_004766"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(219..221),aa:Arg,seq:acg)
     gene            complement(259..351)
                     /locus_tag="ACHY1N_004767"
     tRNA            complement(259..351)
                     /locus_tag="ACHY1N_004767"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(315..317),aa:Ser,seq:gct)
     gene            complement(667..852)
                     /gene="csrA"
                     /locus_tag="ACHY1N_004768"
     CDS             complement(667..852)
                     /gene="csrA"
                     /locus_tag="ACHY1N_004768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HFS4046924.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(1087..3717)
                     /gene="alaS"
                     /locus_tag="ACHY1N_004769"
     CDS             complement(1087..3717)
                     /gene="alaS"
                     /locus_tag="ACHY1N_004769"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFS4046925.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDL
                     SNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNL
                     PIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGVRRIEAVTGEGAITTVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTR
                     QLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLG
                     STIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVKGWVSAKLQ"
     gene            complement(3845..4345)
                     /gene="recX"
                     /locus_tag="ACHY1N_004770"
     CDS             complement(3845..4345)
                     /gene="recX"
                     /locus_tag="ACHY1N_004770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFS4046926.1"
                     /translation="MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKN
                     GPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGIS
                     REATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDI
                     WRNFAD"
     gene            complement(4588..5649)
                     /gene="recA"
                     /locus_tag="ACHY1N_004771"
     CDS             complement(4588..5649)
                     /gene="recA"
                     /locus_tag="ACHY1N_004771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFS4046927.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     IYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNS
                     TPDFSVDDSEGVAETNEDF"
     gene            complement(5729..6226)
                     /gene="pncC"
                     /locus_tag="ACHY1N_004772"
     CDS             complement(5729..6226)
                     /gene="pncC"
                     /locus_tag="ACHY1N_004772"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HFS4046928.1"
                     /translation="MTDSELMQLSEQVGQALKARGATVTTAESCTGGWVAKVITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSEPVVVEMAIGALKAARADYAVSI
                     SGIAGPDGGSEEKPVGTVWFAFATARGEGITRRECFSGDRDAVRRQATAYALQTLWQQ
                     FLQNT"
     gene            complement(6371..7456)
                     /gene="mltB"
                     /locus_tag="ACHY1N_004773"
     CDS             complement(6371..7456)
                     /gene="mltB"
                     /locus_tag="ACHY1N_004773"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HFS4046929.1"
                     /translation="MFKRRYVTLLPLFVLLAACSSKPKPTETDTTTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTT
                     SVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIG
                     VETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFA
                     GAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMAN
                     GQAPGLPNGFKTKYSISQLAAAGLTPQQPLGNHQQASLLRLDVGTGYQYWYGLPNFYT
                     ITRYNHSTHYAMAVWQLGQAVALARVQ"
BASE COUNT         1757 a         2134 c         1834 g         1857 t
ORIGIN      
        1 tgcagatttt ttgataccgc tactaaagcc gtatcaagta agagatggtg catccgggag
       61 gattactcgc cttgcggctc gcccttcggg ccgttgctaa agcaacgtta tcctccctgg
      121 tgcctgcggt tataccgcca cctcttccat accttcatcg ctgaaagtac gtagaatatg
      181 gtgcatccgg gaggattcga acctccgacc gctcggttcg tagccgagta ctctatccag
      241 ctgagctacg gatgcaaatg gcggtgaggc ggggattcga accccggatg cagcttttga
      301 ccgcatactc ccttagcagg ggagcgcctt cagcctctcg gccacctcac cacacgcctc
      361 ttacgagtgc ttcgaagaac ttgtttatcg ctcatcgtcg ctgcgtggcg cacatattac
      421 tttctgagac ttataagtca aacaattttt cctacacttt tatcgtttgc acacttcacg
      481 ttcaattagt ctgtaaaaac gtcaaaaaga gtgttttatc aacagaaaaa tggaggtctg
      541 acagatagta gtaatgcaaa aaaatggaga cttaagttga atgaacggga gtaaagcgaa
      601 aagactatag agtgaaggag aaattttgag ggtgcgtctc accgataaag atgagacgcg
      661 gaaagattag taactggact gctgggattt ttcagcctgg atacgctggt agatctcttc
      721 acggtgaaca gaaacttcct tcggggcatt tacgccaata cgtacctggt tgccctttac
      781 ccctaaaact gtcacggtga cctcatcccc aatcatgagg gtctcaccaa ctcgacgagt
      841 cagaatcagc attctttgct ccttgaaaga ttaaaagagt cgggtctctc tgtatcccgg
      901 cattatccat catataacgc caaaaagtaa gcaatgacaa acacattaca tgtaagcagt
      961 catggcatta cattctgtta aacctaagtt tagccgatat acacaacttc aacctgactt
     1021 tatcgttgtc gatagcgtta atgcgaatgc cgtgaagcga gtccacggca ttgcctgacg
     1081 cttatattat tgcaatttcg cgctgaccca gcctttcaca ctggctaacg ctgcaggtaa
     1141 ggccgcagca tccgtaccac cggcttgcgc catgtcagga cgtccaccac ccttgccgcc
     1201 cacctgctga gcgaccatac caatcagttc ccctgctttc acacgatctg tgacgtcctt
     1261 agatacgcct gcaatcagag aaaccttacc ttcggctacc gttgccagca cgataattgt
     1321 cgaccccagc tgatttttta aatcgtcaac catggtacgc aacattttcg gctcaacacc
     1381 gctaagctcg ctaaccaaca gcttaacacc attaacatca attgccttac tggaaagatt
     1441 tgcgctctcc tgtgcggcag cttgttcttt aagctgttgt agttcttttt ctaactgacg
     1501 cgtacgttcc agtactgagc gcactttatc cgccagatta ttgctatcgc ctttcagcag
     1561 atgcgcgact tcgcttaagc gatcgctgtc tgcatgaacg gtggtgatag cgccttctcc
     1621 ggttaccgct tcgatacgac gaacgcctgc agcagtaccc gattcagaga tgatgcggaa
     1681 cagaccaata tcaccagtgc ggctggcgtg agtaccgcca cacagctcgg tggagaaatc
     1741 gcccatgctc agcacgcgta cacgctcatc atacttctcg ccgaacagcg ccatcgcacc
     1801 tttcgctttc gccgcttcga gatccatgat gttggtttcg atcggcaaat tgcgacgaat
     1861 ctgtgcgttc accaggtctt cgaccgcacg aatctcttcc ggtttcatcg cttcgttgtg
     1921 tgagaagtcg aagcgcagca ccttgtcgtt aaccagtgaa cctttctgcg atacatgagt
     1981 ccccagaacc tggcgcagcg cagcgtgcat caggtgcgtt gcggagtgat tcagacgaat
     2041 acgggcgcga cgagcctcat caacatcagc ctgcacagcg tcgcccactt tcagagaacc
     2101 cgcagcaagt ttaccgatgt gaccaatcgc ctggccgtat ttctgcgtat cttccaccgc
     2161 gaaggagaag ttagcgcctt tcagttcgcc tttatcacca acctgaccgc cggattccgc
     2221 atagaatggt gtttgatcca gcacgaccac agcttcctgg cctgcattga tggcatcaac
     2281 cgctttacca tcaacaaaca gcgcggtcac tttgccgttc agttccagat ggtcatagcc
     2341 tttaaattca gatgcactat caacacggat cattgcgttg taatcggcac caaagccgct
     2401 ggcttcgcgc gcgcgacgac gctgctcttc cattgctgct tcaaaaccag cttcgtcaac
     2461 tttgatgttg cgctcacgac aaacatcagc cgtcaggtca accgggaagc cataggtgtc
     2521 gtacagacgg aaagccgttt caccatccag cgtatcacca gaaagttttg ccagctcttc
     2581 atccagcaac gccagaccgc gctccagagt acgggcaaac tgctcttctt cagtcttcag
     2641 cacctgctca acctgcgcct gctggcgttt caggtcttca cccgcagagc ccataacgtc
     2701 gatcagcgga ccaaccagtt tgtagaagaa ggtttctttc gcgccgagca tattgccgtg
     2761 acgcactgcg cgacgaatga tacgacgcag tacataacca cggttttcat tggacggcat
     2821 tacgccatcc gcgatcagga acgcacaaga acgaatgtgg tcagcgatta cgcgcagcga
     2881 tttattgctc agatcggtcg cgccagtgac tttcgctacc gcctggatca acgtgcggaa
     2941 caggtcgatg tcatagttag agttaacgtg ttgcagcacc gcagcaatac gctccagacc
     3001 cataccggta tctacagacg gcttcggcag cggttccatc gtgccatctg cctggcggtt
     3061 gaactgcatg aagacgatgt tccagatctc aatgtagcgg tcgccgtctt cttccggact
     3121 tcccggaggg ccaccccaaa tgtggtcgcc gtgatcgtag aagatttcgg tgcacgggcc
     3181 gcacggacca gtgtcaccca tctgccagaa gttgtcagat gcgtatggcg cacctttgtt
     3241 atcgccgatg cgaataatac gttcgcgcgg gatcccgact tctttttccc agatttcgta
     3301 ggcttcgtcg tcgctttcat agacggtaac ccacagacgc tctttcggca gggcaaacca
     3361 tttttcgctg gtcagcagtt cccatgcaaa ctgaatggca tcgtgtttga aatagtcgcc
     3421 gaagctgaag ttgcccagca tttcgaagaa ggtatggtga cgcgcggtgt aaccgacgtt
     3481 ttccaggtcg ttgtgtttac cacccgcacg cacgcagcgt tgggaagtgg tagcgcggga
     3541 ataattacgc ttgtcgagcc caaggaacac atccttgaac tggttcatcc cggcgttggt
     3601 aaacaacaaa gttgggtcgt tatggggtac cagggagctg ctggcaacta cctgatgtcc
     3661 cttactatgg aaaaagtcga gaaacgcctg acggatctca gcggtgctct tgctcataat
     3721 tatcctgaaa tcaagctaac gaaatatcgc caccagctcc agcgtgtctt aaccgccggg
     3781 ctggtaactg aaaagtggga ataagataag ttttcttgac tgggaagtaa aataccgtat
     3841 gcgttcagtc ggcaaaattt cgccaaatat cctggatatc ttccatcaga tagccacgat
     3901 agagcagaaa acgctggatc ttaacttttt ctgaaaagac agttggcaaa ggttcaccat
     3961 attttcgcgt cgcctgatcg cgcgccagtg cgcaccagtc gatgtcacat tcacgcatcg
     4021 ctttttctgt cgcttcgcgg gaaatacctt tctgattcag ttcctgacga atacgtgcag
     4081 gtccataacc tttgcggcta cggctggcga taaagcgcgc aacaaatcgg ctgtcatcga
     4141 gatagccatg ttcatggcac caggcaataa cgcgctcgta atcttctgcc gtagcatcaa
     4201 tctcttctgg gccatttttg cccataatcg gtgccgcgag tttacgtcgc agttcttgct
     4261 cactgtgatc gcgcaccgcc agaatgcgta ccgcacgatc caacaggcga gcatatgccg
     4321 ggcgacggga cgttgattct gtcatggcat atccttacaa cttaaaaaag caaaagggcc
     4381 gcagatgcga cccaggtttt gctgataaac agatttaata gtcaatgagt gtgcagaatg
     4441 ttcccgcagg cccaattcgt tagaggatcg aggtgagagt aatttttcac gccagtgctg
     4501 gcctgttccc ctcaccctaa ccctctcccc aaaggggcga ggggaccgtc cgtgcacaca
     4561 ttatctatta tcatcaataa cgaacgatta aaaatcttcg ttagtttctg ctacgccttc
     4621 gctgtcatct acagagaaat ccggcgttga gttcgggttg ctcagcagca actcacgtac
     4681 tttcttctcg atctctttcg cggtttccgg gttatctttc agccaggcag ttgcattcgc
     4741 tttaccctga ccgatcttct cacctttgta gctgtaccac gcgcctgctt tctcgatcag
     4801 cttctctttt acgcccaggt caaccagttc gccgtagaag ttgatacctt cgccgtagag
     4861 gatctggaat tcagcctgtt taaacggcgc agcgattttg ttcttcacca ctttcacgcg
     4921 ggtttcgcta cccaccacgt tttcgccctc tttcaccgcg ccgatacgac ggatgtcgag
     4981 acgaacagag gcgtagaatt tcagcgcgtt accaccggta gtggtttccg ggttaccgaa
     5041 catcacacca attttcatac ggatctggtt gatgaagatc agcagcgtgt tggactgctt
     5101 caggttaccc gccagcttac gcatcgcctg gctcatcata cgtgccgcaa ggcccatgtg
     5161 agagtcgccg atttcgcctt cgatttccgc tttcggcgtc agtgccgcca cggagtcaac
     5221 gacgataacg tctactgcgc cagaacgcgc cagggcgtca cagatttcca gtgcctgctc
     5281 gccggtgtcc ggctgggagc acagcaggtt atcgatatcg acgcccagtt tacgtgcgta
     5341 gattgggtcc agcgcgtgtt cagcatcgat aaacgcacag gttttacctt cacgctgcgc
     5401 tgcggcgatc acctgcagcg tcagcgtggt tttaccggaa gattccggtc cgtagatttc
     5461 gacgatacgg cccatcggca gaccacctgc cccaagcgcg atatccagtg aaagcgaacc
     5521 ggtagagatg gtttccacat ccatggaacg gtcttcaccc aggcgcatga tggagccttt
     5581 accaaattgt ttctcaatct ggcccagtgc tgccgccaac gctttctgtt tgttttcgtc
     5641 gatagccatt tttactcctg tcatgccggg taataccgga tagtcaatat gttctgttga
     5701 agcaattata ctgtatgctc atacagtatc aagtgttttg tagaaattgt tgccacaagg
     5761 tctgcaatgc atacgcagta gcctgacgac gcaccgcatc acggtcgccg ctgaagcatt
     5821 cccgccgggt aatgccttca ccgcgggcag tggcaaaagc aaaccagacg gtgccgacag
     5881 gcttctcttc actgccgcca tccggcccgg cgataccact aatagacacg gcataatcag
     5941 cacgagccgc tttcagtgcg cctatcgcca tttccaccac gacgggttca ctcaccgcgc
     6001 catgctgcgc cagcgtctct tcgcgtacgc cgatcatctg cgctttggct tcgttactgt
     6061 aggtgacaaa tccgcgttca aaccaggcgg agctaccggc aatatcggta atcactttcg
     6121 ctacccaacc accggtacaa gactcggcag ttgttacggt tgcgccacgg gctttcagcg
     6181 cctgcccaac ctgttcactt aactgcatca gttcactgtc agtcatcaca acctctgtca
     6241 gtcaaaaatt tatgccggac aagatagcac tttcgtcagg aagatggtgt tggcgttgca
     6301 attttacgag gaggattcag aaaaaagctg attagccaga gggaagctca cgcccccctc
     6361 ttgtaaatag ctactgtact cgcgccagcg ccacggcttg tcctaactgc cagaccgcca
     6421 ttgcgtaatg ggtgctgtgg ttgtaacggg tgatggtgta gaagttcggc agaccgtacc
     6481 agtactggta gccggtgcca acatccagac gcagcaggct ggcttgttga tggttgccca
     6541 gcggctgctg tggcgttaaa cctgcggcgg caagctgcga aatgctgtac ttagttttga
     6601 agccatttgg caagcctgga gcctgaccgt ttgccattac cgcgacctga tcgcctttca
     6661 cccagccgtg cgctttgaaa tagttcgcca cgctaccgat cgcatcaacc ggatcccaca
     6721 ggttgatatg cccgtcgccg ctgaaatcta ccgcatattg tttgtaagac gacggcataa
     6781 actgtccgta gcccatcgcc ccggcaaagg aacctttcag attgagcgga tcgtcctgct
     6841 cgtcgcgcgc catcaacagg aaggtttcca gctcgccaga gaaatactcc gcgcggcgtg
     6901 ggtagttaaa tgacagcgtt gccagcgcat cgaggatgcg agttttcccc atcacgcgcc
     6961 cccagcgggt ttcaacgccg ataatcccga cgataatttc cggcggtacg ccatacacct
     7021 gccacgcgcg attcaacgca tcttcatact gattccagaa aaccacaccg ttctgcacgt
     7081 tgtccggcgt aataaatttt ttgcgataac gcagccatgc gccgttcgga cctgatggcg
     7141 gtttcaccga tgtggttggt gcctggttat ccatcagccg cagtaccgaa tccagacgtt
     7201 tcgcctggga gagaatttcc tgcaactgct gacgatcgaa accgtgtttg ttcaccattt
     7261 tgtcgatgaa ctgctgggca ttcgggttat tagcgaaatc gccgcccatc tgcatcacat
     7321 tgtgctgcgg ctcaagcagg aagccgccag acggcgttcc ggtggtcgta tcagtctcag
     7381 taggttttgg cttgctgcta caggcggcaa gcaacacaaa aaggggaagc aatgttacat
     7441 aacgacgctt gaacatgagg ggtccattta acagattcaa ccaggggcaa gtatggtaaa
     7501 gcatcacgcc ccgcacaagg aagcggtagt cactgcccga tacggacttt acataactca
     7561 actcattccc ctcgctatcc tt
//
LOCUS       DAZUDJ010000137         7376 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.139, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000137 DAZUDJ010000000
VERSION     DAZUDJ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7376
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.139"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(93..916)
                     /locus_tag="ACHY1N_004774"
                     /pseudo
     CDS             complement(93..916)
                     /locus_tag="ACHY1N_004774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414735.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YaeF family permuted papain-like enzyme"
     gene            complement(970..2688)
                     /gene="proS"
                     /locus_tag="ACHY1N_004775"
     CDS             complement(970..2688)
                     /gene="proS"
                     /locus_tag="ACHY1N_004775"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFS4046930.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYL
                     VKQIKG"
     gene            complement(2800..3507)
                     /gene="tsaA"
                     /locus_tag="ACHY1N_004776"
     CDS             complement(2800..3507)
                     /gene="tsaA"
                     /locus_tag="ACHY1N_004776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HFS4046931.1"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     gene            complement(3504..3908)
                     /gene="rcsF"
                     /locus_tag="ACHY1N_004777"
     CDS             complement(3504..3908)
                     /gene="rcsF"
                     /locus_tag="ACHY1N_004777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HFS4046932.1"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     gene            complement(4026..4841)
                     /gene="metQ"
                     /locus_tag="ACHY1N_004778"
     CDS             complement(4026..4841)
                     /gene="metQ"
                     /locus_tag="ACHY1N_004778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HFS4046933.1"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKDSPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(4881..5534)
                     /locus_tag="ACHY1N_004779"
     CDS             complement(4881..5534)
                     /locus_tag="ACHY1N_004779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HFS4046934.1"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTVSAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     gene            complement(5527..6558)
                     /gene="metN"
                     /locus_tag="ACHY1N_004780"
     CDS             complement(5527..6558)
                     /gene="metN"
                     /locus_tag="ACHY1N_004780"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009276 - Gram-negative-bacterium-type
                     cell wall [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HFS4046935.1"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     gene            6746..7318
                     /gene="gmhB"
                     /locus_tag="ACHY1N_004781"
     CDS             6746..7318
                     /gene="gmhB"
                     /locus_tag="ACHY1N_004781"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HFS4046936.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPA"
BASE COUNT         1815 a         1906 c         1869 g         1786 t
ORIGIN      
        1 catataatgc aacattttga attagcacga ttttgtaggc cggataaggc gtttacgccg
       61 catccggcat tttgtgcacg aggctggctt tatcactgag tcagcccaac aaagcgaccc
      121 gccttgatat aaatcccagg cttcaggtgc ccaacatact gtaactgcgt ttctggctta
      181 aacgcagaga catcaccaat acgcatatgc atcagatcgg cagggctaat ccagcccgat
      241 tgcgccagtg taagtggatg cccggctttg gcaaaggcat ccgtgacaaa ttccgaacaa
      301 aaccacgact ttttgtctcc ttcgcccaca ctgcttaact gcgctttcgc caggccgctg
      361 acgcactttg gcgaaaatcc tcggagaacg gattcagtga gcacatctgg cgagtcacca
      421 taaagggaat aaattcgaca atgccgcgat agttataacc gctatctttg attttattgg
      481 caaacgcggt gatatctgtg gcttgttgcg gggtaagatc cgggactcgt aagacgaaaa
      541 gcttatcact atgcttcatc gcttttttaa gggaaacaat ctggacgcca gcgcctgtcg
      601 cttctgcaac gttattatca cccagaaaga ttgcaacgtg actcacagag gaagtgctga
      661 agacgcggat tccaaatgag gttaccccaa ggcttgagga gaacagcaaa tcgccgggtt
      721 tgagatcagg tgccgttatt tcttttattg attgttcggt gaaagagctt tgatgctgga
      781 atttgacagc ccatgttttt gcctcggcat ctactgctgt ggctgatggg tctggctggc
      841 tgatatcaac ggtacaagcc gaaagtaaaa gaaagctggg gagaaacagg cggcagtacg
      901 cctttggttt atccatttta tacaatccat gtaaaaaaag ggccctgaaa ttcaggaccc
      961 tttctggcat cagcctttaa tctgtttcac cagatattcg acgatgtcac cagtcttaat
     1021 taactgtttc tcgccgttgc gacgatattt atattcgata tcgtcgttgt cgaggttacg
     1081 gtcgcccagc acaatagtgt gcggaatacc gatcagttcc atatcagcaa acatcacgcc
     1141 cggacgctct ttgcggtcat ccagcagcac ttcgatacct tgtgcacgca gttcgctgta
     1201 cagtttctca gcaagctctt gtacgcggaa ggatttgtgc atgttcatcg gcagaatcgc
     1261 cacctggaac ggcgcgatag cgtcaggcca tacgatgcct cgttcgtcgt agttctgctc
     1321 aatcgccgca gctaccacac gcgttacccc gataccgtag caacccatcg tcaggatttg
     1381 gttacggcca tcttcaccct gtacggaggc tttcagtgct tcggagtact tggtacccag
     1441 ctggaagatg tgaccaactt cgataccacg tttgatcagc agcgtaccct ggccatccgg
     1501 gcttggatcg ccagccacca cgttacggat atctgcaact tccggggtag cgacatcgcg
     1561 atcccagttg atgccgaagt agtgtttacc atcgatgtta gcaccagcag cgaaatcact
     1621 catcgccgca acggtacggt caatcaccac cggaatcggc atgtttaccg gacccagtga
     1681 acccggaccg gctttaacca cggcacgaat ttcttcttcg gtcgcgaaag tcagcgggct
     1741 tgcaacctgc ggcagttttt ctgctttaac ttcgttcagc tcgtgatcac cgcgcaccag
     1801 cagcgcaacc agcgggaagc tactgccttc aaccgcttta accagcagag tcttaaccgt
     1861 tttctcaatc ggcagattga actgttcaac cagttccgcg atggttttcg cgttcggcgt
     1921 atcaaccagc gtcatttcct gggtagcagc agcgcgcggt tctttcggcg cgatagcttc
     1981 tgccagttca atgttcgctg catagtcaga ggtgtcggag aagaccacat cgtcttcacc
     2041 gctctgcgcc agcacctgga attcgtgaga ggcgctgccg ccgatagaac cggtgtcggc
     2101 ttgtacggcg cggaaatcca gccccatgcg gctgaagatt ttgctgtagg ccgcatacat
     2161 tgcatcgtag gtttcctgca gggattcctg agaagtatgg aaagagtaag catctttcat
     2221 caggaattcg cgggaacgca tgacgccgaa acgcggacgc acttcgtcgc ggaacttggt
     2281 ctggatctga tagaagttca gcggcagctg tttgtaagag ctaagctcgt tacgaatcag
     2341 gtcagtgata acttcttcat gagttgggcc gagtacgaac ggacgctcgc cacggtcaac
     2401 aaaacgcagc agttccggac cgtactgttc ccaacgacca ctctcttgcc acaaatcagc
     2461 tggctgaacc accggcatcg acacctcgat cgcaccggcg ttgttcatct cttcacgcac
     2521 gatgttttcg acttttttca gaacgcgcac gccggtcggc agccaggtat ataacccgga
     2581 ggccagcttg cggatcatcc cggcgcgcag catcagctga tggctgatca cctcggcgtc
     2641 ggcaggtgtc tccttgagag tggagagcag gtattggcta gtacgcatgt tgttacggtt
     2701 ccagttggaa ggtagaacag gctcaaggcg agcctgggac aaaaaaaagt gatttagttt
     2761 accagtgcaa aagaaatgtc aaaagagaag ggcgtgaatt taacgcggtt ccagcgcaaa
     2821 gacttcaaaa cctgcgtcgg tgacgcgcca gcgaacgtta aaatcatgta gccagacggc
     2881 ataggttttg cccgtttcct cacctttacg ataggccggg cgtgggtcct gcgccagtac
     2941 ttcgcggata aacagcgtta actgcggata acgcttctcc agcgtcaaaa gctgcttttc
     3001 gacctctgcg gtaaaactca ccgccatctc tgccgctggc gcactttgcg catagctggc
     3061 actggcatcg ggaagcgatt cggcaaaggg gagatacggt ttgatatcca ctaccggcgt
     3121 accatcgacc agatccagac tgccgagctt cagaatcacg ctgtctttat ggcaaacaac
     3181 ctctttcagc tctaccagcg acataccaat tgggttaggg cggaaagtag agcgtgttgc
     3241 gaaaaccccc attctggcgt taccgccgag gcgcggtgga cgcacagtcg gacgccagcc
     3301 gccttccatc gtttgatgaa agacgaaaag gatccataaa tggctgaacg cttccaggcc
     3361 gcgaacggcg tcggcctggt tgtagggagc aatgagatgc agttcgccgt tggcgctttt
     3421 taccagacct ggctggcgcg gaacggcgaa tttttcttta tagggcgagc gaataacgcc
     3481 tatttgctcg aactggaaac tgctcatttc gccgtaatgt taagcgcaga gccgatacat
     3541 acagcctgac gatagcagcc tggcgtaccg ctggtgactt cgcagctatg cagtaatacc
     3601 gcattggcct tcattttcga ggcgttgatt tgcatccgct tacgcgcggt tggaatgctc
     3661 ggcggagagt cctgattaga ggcctggcaa gagtcgccac tgacttcacc gagatcgcgg
     3721 aacggtttgc cgactaattc ttctgcattg gtataaattc ggaccggcgt ggcgcgcggc
     3781 gctttcggtt ttgcaggctc cgctttcggc tggggtgcag tgctttgaac gggttcgaca
     3841 ggggatctgc ttaacatgga acagccgctt agcatgagtg ctactaaaca gatcggtaaa
     3901 gcacgcatag tatttcctca atgtatgatc aaaacgtcaa tattgaatca ggagcttgta
     3961 aaaatgacaa gacgggcaag cgcccgtcct gaatgatatt acaaattgtg gaaacagcct
     4021 aaaaattacc agcctttaac agcgccgccg ttaaacactt tgtttgctgc ttcgtaaact
     4081 tcatcagact gataagcctg gacgaatttc ttcacgttct cggcgtcttt gttatcttca
     4141 cgcgttacga tcaggtttac gtacggggag tctttatctt cgacaaagat accgtcttta
     4201 gctggagtca ggccaatctg gctggcatag gtggtattga taactgccag agcgatttgc
     4261 gcgtcgtcca gagatcgagg cagctgcggt gcttccagct caacaatttt cagatttttt
     4321 gggttctcaa caacatcaag aacggtcggc agcaggccaa cgccatcttt cagtttgatc
     4381 aagcccactt tttgcagcag cagcagtgaa cgaccaagat tagttggatc gtttggcacg
     4441 gcaacctgcg aaccatcctg cagttcatcc agtgatttga ttttcttgga gtaaccagca
     4501 atcggataaa caaaagtgtt gcctactgcg accagtttgt agccacgatc tttcagttgc
     4561 tgatcaaggt acggtttatg ctggaaggcg ttggcgtcga tatcgccttt gctcaatgct
     4621 tcgtttggca gaacatagtc gttgaaggtt accagctcaa cgtccaggcc atatttgtct
     4681 ttcgcaactt tctgcgcgac ttctgctacc tgctgttcgg caccaacaat cacgccgact
     4741 ttaatgtggt ttggatcttt ttcatcctga ccgcagccta ccagtgccag tgatccaatc
     4801 agggctccca ctgccgcaaa ggttttgaat ttgaacgcca taccttattc cttcttcaat
     4861 tatttatgtt gtgttgaacg ttacttgcga gtgacagccc ggacgatgcg gtcgcctgcg
     4921 aactgaatta aataaaccag aatgaccagc aataccagta ccgtattcat caccgtcgcg
     4981 ttatagccga tgtagccata ctgatagcca atctgaccta aaccaccggc accgactgca
     5041 ccacccatcg cggaataacc gaccagggta atcagggtga tagttgccgc attcaccaga
     5101 cccggcaatg cttccggtaa cagcacttta cggacgatct gcatcggcgt ggcacccatt
     5161 gcgcgggaag cttcaattaa cccggttggg atctccagca gagcgttctc gaccatacgg
     5221 gcaataaacg gtgctgcacc aacggttaac ggaacaatcg ctgcctgcaa accaatcgat
     5281 gtaccaacaa taacgcgggt aaacggaatc atccatacca gcaagataat gaacgggata
     5341 gaacggaaaa tgttcacaat cgcagaaacg gtacgataca gcttcgcgtt agcaataatt
     5401 tgccccggac gcgtgacata aagcagaacg ccaaccggca gaccaatcac aaagccaaaa
     5461 aaaccggata cgaaggtcat tgccagcgtt tcccatacgc cacgaaccag cagccacatc
     5521 atcggctcag acataaccca gtacctctac ttttacatgg tgttcctgca gccaggcaat
     5581 ggcggcttgc gtatcttgtt gtgtgccgtg catttcagtc agcatgatgc cgaacttaac
     5641 gccaccggcg tagtccatct gcgcgctaat aatgttgttg ttgacgttga aacgacgcgc
     5701 ggtttcagaa agcagtgggg catcgaccga ctgaccggta aactccagac gcagcatcgg
     5761 cacgcagtca gtgaatggct ccgcttgcag acgttcctgg taatcttccg ggatatccag
     5821 atgcagggtc gactgaataa acttctgcgc caacggcgtt ttcggatgcg aaaacacttc
     5881 acttaccgtg tcctgctcga tcagttcgcc attgctgatg accgccacgc aatcacaaat
     5941 acgctttaca acgtccattt cgtgggtgat caacagaatc gtcaaaccca gacggcggtt
     6001 aatgtctttc agcagctcga gaatagaacg tgtcgttgcc gggtccagcg cgctggtggc
     6061 ttcatcacac agcaatactt tgggattgct ggctaacgca cgggcaatcg ccacacgctg
     6121 tttctgccca ccggaaagat tcgatgggta gctatcatgc ttatcgccaa gaccaaccaa
     6181 tgacagcaat tccgtcacgc gacgtttgat ctcgtctttc ggtgtgttgt ccagctccag
     6241 cggcagagcc acgttgccaa aaacagtacg cgaagagagc aggttaaaat gctggaaaat
     6301 cataccaatc tggcggcgag ctttggtcaa ctcggattct gacagcgtgg tcagttcctg
     6361 gccatcgacc agcacgctac cctcggttgg gcgctccagc aggtttacac aacgtataag
     6421 cgtactctta cccgcgcctg aggcaccgat aacgccataa atttgtccag ctggcacatg
     6481 caggctgacg ttgttcaacg cctggatggt gcgggtgccc tggtggaaca ctttggtgat
     6541 attcgaaagt tttatcattg attatttatt atcgtcatta agttagtcgt ggcatctcga
     6601 atgcctgaaa cgggcaacgc cgtcaatgaa atggatgtta aggcatccag acgtctaaat
     6661 caatcaggtt tatgcgaaga gcactttctt gcaggtcgaa acatgcgata ctagcgtcac
     6721 atgccttatt aaggagctat aaaaggtggc aaagagcgta cccgcaattt ttcttgaccg
     6781 tgatggcacc attaatgtcg atcacggcta tgtccatgag atcgacaact ttgaatttat
     6841 cgacggtgtt attgacgcca tgcgcgagct aaaaaaaatg ggctttgcgc tggtggtagt
     6901 aaccaaccag tctggcattg ctcgcggtaa atttaccgaa gcacagtttg aaacgctgac
     6961 cgagtggatg gactggtcgc tggcggaccg agatgtcgat ctggatggta tctattattg
     7021 cccgcatcat ccgcagggta gtgttgaaga gtttcgccag gtctgcgact gccgtaaacc
     7081 acatccgggg atgcttttgt cagcacgcga ttatttgcat attgatatgg ccgcttctta
     7141 tatggtgggc gataaattag aagatatgca ggcagcggct gcggcgaacg tgggaacaaa
     7201 agtgctggtg cgtacgggta aacctattac gcctgaagca gaaaacgcgg cggattgggt
     7261 gttaaatagc ctggcagacc tgccgcaagc gataaaaaag cagcaaaaac cggcataatg
     7321 attaaaagat gagcaattga aataaaaatg catttttcca cttgtcttcc tgagac
//
LOCUS       DAZUDJ010000138         7283 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.140, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000138 DAZUDJ010000000
VERSION     DAZUDJ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7283
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.140"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(164..526)
                     /locus_tag="ACHY1N_004782"
     CDS             complement(164..526)
                     /locus_tag="ACHY1N_004782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HFS4046937.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKAT
                     LEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTA
                     LGREMGLQEMTGFSKTAF"
     gene            811..1020
                     /gene="yibT"
                     /locus_tag="ACHY1N_004783"
     CDS             811..1020
                     /gene="yibT"
                     /locus_tag="ACHY1N_004783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YibT"
                     /protein_id="HFS4046938.1"
                     /translation="MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPD
                     ESVPLYLQRLEYYRRLYRPKQVEGQ"
     gene            complement(1032..1619)
                     /gene="mtlR"
                     /locus_tag="ACHY1N_004784"
     CDS             complement(1032..1619)
                     /gene="mtlR"
                     /locus_tag="ACHY1N_004784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol operon repressor MtlR"
                     /protein_id="HFS4046939.1"
                     /translation="MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRS
                     FLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVI
                     NRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
                     YAMQIQRYQQAVRSTMVLSLTELISRISLKKAFQK"
     gene            complement(1619..2767)
                     /gene="mtlD"
                     /locus_tag="ACHY1N_004785"
     CDS             complement(1619..2767)
                     /gene="mtlD"
                     /locus_tag="ACHY1N_004785"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFS4046940.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGETEQVDTVSGVDAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKG
                     LVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYSLPHKNLIQGIAGAMHF
                     RSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ"
     gene            complement(2862..4775)
                     /gene="mtlA"
                     /locus_tag="ACHY1N_004786"
     CDS             complement(2862..4775)
                     /gene="mtlA"
                     /locus_tag="ACHY1N_004786"
                     /EC_number="2.7.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HFS4046941.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPIVEALSKM
                     LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVCAAMAVSFVVSAILL
                     KTSKVKEEDDIEAATRRMQDMKAESKGTSPLSAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHTENEVKVKDSLKDSFDDSSANLFKLGAENIFLGRKAA
                     TKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT
                     SVDEVLELLAGRK"
     gene            5312..5674
                     /locus_tag="ACHY1N_004787"
     CDS             5312..5674
                     /locus_tag="ACHY1N_004787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HFS4046942.1"
                     /translation="MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAI
                     HTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIAALSDRISRL
                     EHQLAAEKKTDYSTFPEI"
     gene            5677..6813
                     /locus_tag="ACHY1N_004788"
     CDS             5677..6813
                     /locus_tag="ACHY1N_004788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFS4046943.1"
                     /translation="MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLI
                     LLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVRYQAR
                     VDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS
                     ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLE
                     QTVIRAPSNGYVTQVLIRPGTYAVALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGD
                     DAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPND
                     DIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH"
BASE COUNT         1774 a         1824 c         1808 g         1877 t
ORIGIN      
        1 tatttcggta aaaatgcatt ttcagaatat caaccagcgg taaatcgaag taaagggagt
       61 gaattgtttg gtaattaggc gagtagacag gagagtcccc gcattgacca gctaaggcaa
      121 gccagatgcg ggttgatatg atcgaaccag tcgtctgagg cgcttaaaac gcagtcttag
      181 agaatccagt catctcctgc aggcccattt cacggcccag cgcggtcatt gggtgcacaa
      241 ccaccagtcc gcgaacactt ttcttcagct tgcccatatc agcctgctct tttttggtaa
      301 ttgcgcgctg aaacggcatc ttcatcagct tctgtgcttc tttactcagt ttttggctat
      361 gaacttcacg caggcgagca atttctgctt ccagcgtggc tttctctttt tccagctcgg
      421 catatttgtc tgcggcttca accagcgaca gatcggcctg ctggtggcgg atggcgtcca
      481 gacgatcgct gagacgtttg atttcgtttt tttcgacttc tttcatgtga tggcttctga
      541 taaagataaa tttatagccc ctagtatgcg cgaccaggtg ctttgttcac aactgatgac
      601 attgcaatag ttctgtaacg taatcattaa catgcttaaa aactacgcaa tttattgatt
      661 aattaagaaa tctatagaaa aaagataata aacagcagcg gatgattatt gaggattcag
      721 cacgttttcc ttaatgtcat ctttaccggg aacctaaact aaaattggcg gccgcgcatt
      781 cccggcgcgg ggtaatacgg agatatcatc atgggcaaat taggtgaaaa cgttccgctt
      841 cttatcgata aagccgtaga tttcatggca tcaagccagg cgttccggga gtatctgaaa
      901 aaacttcctc cccgtaacgc gattccgtcc ggaatacccg atgaaagcgt gccgttatat
      961 ctacaacgtc tggagtatta tcgtcggctt tatcggccga agcaggtaga ggggcagtaa
     1021 gcagacgttg cttacttttg aaaggctttt tttaagctga ttctggaaat cagctcagtc
     1081 agtgaaagga ccattgttga tcgcacagcc tgttgatagc gctgaatttg cattgcatac
     1141 aaactggagt ctgctggttc aaactgtggc ggcggtggta acgccgccac gcagtgcagt
     1201 tcaccaaagg gtccaaggat ctcgtcgtcg gtaaaggcgt actcgttgcc gtcgtgattt
     1261 agttcttcac gcaatgccat cagcagctcc gcatcttcgt attcctggcg gttaatgacg
     1321 cccaacccgt aaatgagttt taaacgcaca gaaagatcgc ccagcggacc gtcgccgtcg
     1381 agtaacggtt ctacagcata cttcaccgcg taatcgtctt tgcggaatac ctgaagcacc
     1441 agaagattta ccgcctcggt caaaagctcg acggcggtga tcagaaagct tcgcacggtt
     1501 ttgccagcat tcagacgctc aagcacacgg ttttcaaagg cctgggtttg ttccattgtt
     1561 gcctgcatat ctgacaatct gttattcggg cgcagggtgt cctgcgcctg gtccaccatt
     1621 attgcattgc tttataagcg gttaccgcct cggatacaac ctcgctgttg gcatcaagac
     1681 cggaaatctg tgccagcgcc gcctgcggac ctttgtcagc gatcagtgct gccagttcct
     1741 gagcctgcgg atcatcttca ctgcggaagt gcattgcacc agcaatcccc tgaatcagat
     1801 tcttgtgcgg aaggctgtat tccagcgtac cgagcagtgg cttgatcaga cggtcgccag
     1861 cactcagttt acgcagcggc tgacggccta cgcgctctac atcatctttc agatacgggt
     1921 tctcaaaacg accgaggatt ttctggatgt acgccgcatg tttgtctgcg tcaaagccgt
     1981 agcgcttgat cagtaccgca ccactttctt ccatcgcacc ttttaccacc gcgcggattt
     2041 tctcgtcgag aatagcgtca cgaatggtct gatgaccagc cagttttccg aggtacgcgg
     2101 ttatagcatg acccgtgttc agggtgaaga gtttacgttc gacaaatgcc atcaggttgt
     2161 cggttaactc catgcctggg atgttcggca gtgcgccttt gaactgcgtt ttatcgacaa
     2221 tccattcgct gaaagtttct accgtcactt ccagcggatc gttagttgcc gaagccgaag
     2281 gcggtacgat gcggtcaacg gcggaatcga caaagccaac gtgttcttct acccacgctt
     2341 tggcgtcttc cggcagggcg ttcatcacat ggcctttcag ctgcgtggta ccgcgtacca
     2401 tgttttcaca ggcgatgatg ttcagcgggg attcattacc ttgttcttta cgtttcacca
     2461 gccctttggc gatagccgga gcaatacgtt ccagcacaac cgggccaacg gcggtagtga
     2521 ctaaatcgac ctgagcaatc agatcaacga catcatcacc aatgctgctg acagcatcga
     2581 cgccggaaac ggtatctacc tgctcggttt caccaaccac atgaacctga tagctatgac
     2641 gggcattcag ggcatcaagt accacctgat tgacatcggc aaacgtcagt tggatacccg
     2701 cgtctgccag cagtttaccg ataaagccac gaccgatatt acctgcgcca aaatgtaatg
     2761 ctttcatagt attaaccttc atcaatgttt ttacccgaga gggctggggt gaggcttttc
     2821 cctcacccaa accctctccg tgaggagagg gtaggattgg attacttacg acctgccaac
     2881 agttccagca cttcatccac gctggtggtg tgtgccagac gctcgatgac ggactcatca
     2941 tccagtgcat tggtcaggct ggtgataacc tgaatgtgct cgttgttacg ggctgcaata
     3001 ccaatcacca gacgggcaat gtcatcttct tcttcaccga agcgcacgcc ttccgggtac
     3061 tggcagaaca ccacgcccgt tttcagtacg cgatctttcg cttcaaccgt accgtgtggc
     3121 accgcgatag actcacccag ataagtcggg gtcagttttt cacgatccag catcgcctga
     3181 acgtattccg gctcaacgta accgcctttc accagctgct cgccagcaaa acgaatcgct
     3241 tcttctttgg ttgctgcttt gcgaccgagg aagatgttct ccgcgcccag tttgaacagg
     3301 ttagcactgg aatcgtcaaa gctgtctttc agactgtctt tcactttcac ttcgttttca
     3361 gtatggcgct gggcagcaac cagacgttcg gttaggctgg tgtacaggcc gctgtcgagg
     3421 aagttggtca gcgaaatatg ctgcgcctgc ggaacctggc gcatagcgcg ttcggtcagg
     3481 tcacggtgag tgatgacgag gtccacatct ggcggcaggt tgttgatcgc gctgttagtg
     3541 accgaaatct gtgacagacc tgcatcctga attttcttac gcagcacgcc tgcgcccatc
     3601 gcactggaac ccataccggc gtcacaggca acgatgattt tacgtacgtg gctcaggtcg
     3661 ttagtcacat cgcccgcaga cagcggagat gtgcctttag actcagcttt catgtcctgc
     3721 atacgacgag ttgctgcttc aatatcatct tcttctttca ctttgctggt tttcagcaaa
     3781 atagcagaga caacgaagga gacagccatc gccgcacaca cacccgcgat gttagcgaaa
     3841 taagcacctt ttggtgtcat cgccagtaca gcaaggatag aacccggaga tgccggagaa
     3901 accagaccac cgcccaggat agtcagcgtg aacacgccag tcataccgcc gaggatgact
     3961 gcgaggatca gacgcggatt catcagcaca tacgggaagt agatttcgtg gatacccccc
     4021 aggaagtgga tgattgccgc accgcccgca gactgtttag cgctaccacg accaaagaac
     4081 atgtacgcca gcagcacgcc catacctgga cctgggttag cttcaatcag gaagaagatt
     4141 gatttaccca gttcatggga ctgctgaata cccagcggcg agaagatacc gtggttaatg
     4201 gcgttgttga ggaacaggat tttcgccggt tcaacaaaga tagacgccag cggcagcatg
     4261 tcatggacaa ccatgaagtt aacgcccgca gccagcattt tggacagggc ttcaacaatc
     4321 gggccaatgc cgaggaatgc cagaatagcg aggatcatcc cgatgatgcc tgcggagaag
     4381 ttattcacca gcatctcaaa accggatttg atcttaccgt ctacccagcg gtcgaagtgc
     4441 ttaatgcacc agccgcccag cggacctgca atcatagaac cgaggaacat cggcatgtct
     4501 gcgccgacga taacgcccat ggtggtgatg gcaccgacta cgccgccacg ttcgccgcct
     4561 accagcttac caccggtata accgatcagc agcggcagga gataagtgat catcggcccg
     4621 accagcttcg ccagcgtctc gttcggtaac caccctgttg gaataaataa cgcggtgatg
     4681 ataccccacg cgataaacgc gccgatattt ggcatcacca tgttgctgag gaaacgacca
     4741 aagctttgca ctttgatctt aatatcggat gacataaaaa caccccttct tatgtttgct
     4801 gtcgcgcagg ctggaagccc gaggtttttt gttaatgtgg cggcagaggt agccggacct
     4861 tgtagatact gcgaaatctg gcactgaatc ggttaactgt ccagtcgacg gccttttgtg
     4921 tgatatcaat cacataaata tagggggtag agaggtaatt gacgtgacgt tcatcacaaa
     4981 acgcttgtgt aaaaaagcaa caaggcggcg attttcgcta aaaatggcat ttaaatgtga
     5041 gtagtgtcac atttttgttt tgatggtttg ttgaatcttt gtgatctgaa tcacaagata
     5101 ttttcttacg gcgttcacct gatgtgatct acagcatgtt atgccttcgt catacaatcg
     5161 ttatgtaact aagcaactca tcacctctaa aaattattct ttggtgttat ggcgagaatc
     5221 gcgaacccgg attattgtca aaatatcagc ctgactccct tctggctgcc agcccaaaaa
     5281 caacactgat aaacgtgaat ccgaggcaga tatgtttcta aactatttcg cgttgggagt
     5341 gctgatcttc gtctttctgg tgatttttta tggaatcatc gcgatacatg acatccctta
     5401 tctgattgcc aaaaagcgca accatcccca tgccgacgct attcatacgg cgggctgggt
     5461 gagcctgttt actctgcatg ttatctggcc gtttctgtgg atctgggcga cgctctatca
     5521 accggagcgt ggctggggta tgcagtcaca tgttgcgtcg caggagaaag cgactgaccc
     5581 ggaaatcgcc gcactttctg accgaatttc ccggctggag catcaactcg ccgccgagaa
     5641 aaagactgac tattccacgt tcccggagat ctaattatgg atctattgat tgttttaact
     5701 tacgtggcgc tggcgtgggc ggtctttaaa atcttccgca ttccggtaaa tcagtggacg
     5761 ctggcgacgg cggcgctggg aggcgtgttt ctggtgagtg gtttgatttt gttgatgaac
     5821 tacaaccacc cttacacttt taccgcgcaa aaggcagtga tagcgatccc tatcacgcca
     5881 caggtgacgg gaattgttac tgaagtcact gacaagaata atcagcttat tcaaaagggc
     5941 gaggtgcttt ttaagctcga cccggttcgt taccaggcgc gagttgacag acttcaggct
     6001 gacctgatga cggcgacgca taatataaag acgctgcgtg cgcagctcac tgaagcgcag
     6061 gccaacacca cccaggtttc agcggagcgc gaccgtctgt ttaaaaatta tcaacgttac
     6121 ttgaaaggca gccaggcggc ggtgaatccg ttctcggaac gtgacatcga cgatgcgcgg
     6181 caaaatttcc tcgcgcagga tgcgctggtg aaaggctcgg tggcggagca ggcgcagatc
     6241 cagagccagc tcgacagtat ggttaacggc gagcaatcgc agattgtgag cttaagagcg
     6301 caacttactg aagcaaaata taaccttgag cagactgtca ttcgcgcgcc gagcaatggc
     6361 tacgttactc aggtactgat ccgcccaggt acatacgcag ttgccttgcc gctgcgtccg
     6421 gtgatggtct tcatccccga gcaaaaacgg caaattgtcg cccaatttcg gcaaaactcg
     6481 ctgttacgtc tgaaacccgg cgatgatgcg gaagtggtgt ttaacgcgct gcctgggcag
     6541 gtgtttcacg gcaaactgac tagtatttta cctgtcgtgc caggcggttc ttatcaggcg
     6601 cagggggtat tgcaatcatt aacggtcgtg cccggcacgg acggtgtgct gggaaccatt
     6661 gaactggacc ctaacgatga tatcgatgcc ttacccgacg gcatctacgc ccaggtggcg
     6721 gtttactccg accatttcag ccatgtttcg gtgatgcgga aagtgctgct aagaatgacc
     6781 agctggatgc attatcttta tttggatcat tgagggggag gggggagatt atggaacttt
     6841 gctccttgta aggactaatt atttttgcat attacttcat tagctgcgat gatttttctt
     6901 taatattcat tatgttaata agttctggat gagtgtgctc tcattggatt ttttatccgt
     6961 cttgttctgc cgcaggatga gactatacat cgtcgagatc gcaatgatga tatgagttgt
     7021 tcctcctgcg acggctctaa tcaaaaaaga gcaggagtgc ttttccatct attgcgatga
     7081 tggctttatt atctgaagga tgacagtcac atttaaaaaa tatttaatct atagatcaca
     7141 atgtagggtc atggaatata tgtatacaac tattttcttc ttcactttta attatcgtat
     7201 tcattataaa actaagttaa aaaaactcct ggagagtgtg ttattaatat atttttaaat
     7261 aaaattaagt tatcattcat cga
//
LOCUS       DAZUDJ010000139         7192 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.141, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000139 DAZUDJ010000000
VERSION     DAZUDJ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7192
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.141"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..485)
                     /locus_tag="ACHY1N_004789"
     CDS             complement(<1..485)
                     /locus_tag="ACHY1N_004789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308843.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046944.1"
                     /translation="MLSSCIGVVMKDGALLRSSSLFIAYMGCLGWGSAYFYGWGTSFY
                     YGFPWWIVGAGVDDVARSLFFAVIVIAIFLIGWGIGVVFFFAVKRKHSMQELNVFRLY
                     FAVELLFVPAIIEFSILRQKIQVPLLLLSAAIALAVTISIRSYGRFLSVSCFYDKPFI
                     K"
     gene            complement(670..1359)
                     /locus_tag="ACHY1N_004790"
     CDS             complement(670..1359)
                     /locus_tag="ACHY1N_004790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage antitermination protein Q"
                     /protein_id="HFS4046945.1"
                     /translation="MNTQYLQYVREQLMAATADLNGATKGQLEAWQEHAQFDTGTYKR
                     KKPRILDVVTGKMITLDNTPTSGKQSYAKGSSIALVSPVEFSTSSWRRAVLSLDEHQK
                     AWLLWCYSESVRWGHQVTITQWAWSEFKDLLSNRKIAGKTLDRLKTLIWLAAQDVKSE
                     LAGREAYEYQTLASLVGVTTKNWSETFTERWVAMKHIFLQLDSDALLLVTRTRSKQKA
                     AFLQQNIAKLD"
     gene            complement(1374..1496)
                     /locus_tag="ACHY1N_004791"
     CDS             complement(1374..1496)
                     /locus_tag="ACHY1N_004791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000971054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcG family protein"
                     /protein_id="HFS4046946.1"
                     /translation="MMSESYISELLRCRWGLLCLCRFPDSVLNDYRMLKNYAKI"
     gene            1835..2794
                     /locus_tag="ACHY1N_004792"
     CDS             1835..2794
                     /locus_tag="ACHY1N_004792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A deacylase LpxR family protein"
                     /protein_id="HFS4046947.1"
                     /translation="MKKSVIAGVFIALSFTTCSAIANSLALSLANDDAGKFQPILNDI
                     YGNKHENRDDYSQGLFLGYSHDISDSSQLSLHIAQDIYSPSGSNKRHNTAVTGDRAFS
                     AYTHTGIEWNSLANDWIRYRLGTDIGVVGPDAGGQKVQNKAHEIIGAEKYHAWDDQIE
                     NRYGYTVKGMLSMTPSMDILGANVGLYPEVSAVTGNLFQYVAYGATIAIGNDKTFNSD
                     NGFGLLAPRGLMHMSDTSGFKYKIFAGMERRDVNRNYTLEGKTIQTKQTTVSLNKTVD
                     EYQVGATIGYAPVAFTLAFNKVTSEFKTGDDYSFINGAITFFF"
     gene            complement(2938..3009)
                     /locus_tag="ACHY1N_004793"
                     /pseudo
     CDS             complement(2938..3009)
                     /locus_tag="ACHY1N_004793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311528.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
     gene            complement(3006..3671)
                     /locus_tag="ACHY1N_004794"
     CDS             complement(3006..3671)
                     /locus_tag="ACHY1N_004794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HFS4046948.1"
                     /translation="MNIYERIDGSKYRNIWVAGDLHGCYTNLMNKLDTIGFDTKKDLL
                     ISVGDLVDRGTENVECLELITFPWFRAVRGNHEQMMIDGLSERGNVNHWLLNGGGWFF
                     NLDYDKETLAKVLAHKAEELPLIIELVSKDKKYVICHADYPCDKYEFGKPVDHQQVIW
                     NRERISNSQDGIVKEIKGADTFIFGHTPAVKPLKFANQMYIDTGAVFCGNLTLIQVQG
                     EGA"
     gene            complement(3668..4279)
                     /locus_tag="ACHY1N_004795"
     CDS             complement(3668..4279)
                     /locus_tag="ACHY1N_004795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinG"
                     /protein_id="HFS4046949.1"
                     /translation="MAKPARRRCKNDECREWFHPAFANQWWCSPECGTKIALERRSKE
                     REKAEKAAEKKRRREEQKQKDKLKIRKLALKPRSYWIKQAQQAVNAFIRERDRDLPCI
                     SCGTLTSAQWDAGHYRTTAAAPQLRFDERNIHKQCVVCNQHKSGNLVPYRVELISRIG
                     QEAVDEIESNHNRHRWTVEECKAIKAEYQQKLKDLRNSRSEAA"
     gene            complement(4272..4442)
                     /locus_tag="ACHY1N_004796"
     CDS             complement(4272..4442)
                     /locus_tag="ACHY1N_004796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein NinF"
                     /protein_id="HFS4046950.1"
                     /translation="MIDPNRSYEQESVERALTCANCGQKLHVLEVHVCEHCCAELMSD
                     SNSSMHEEEDDG"
     gene            complement(4439..4621)
                     /locus_tag="ACHY1N_004797"
     CDS             complement(4439..4621)
                     /locus_tag="ACHY1N_004797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016063117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NinE family protein"
                     /protein_id="HFS4046951.1"
                     /translation="MRRQRRSFTDIICENCKYLPTKRSRNKRKPIPKESDVKTFNYTA
                     HLWDIRWLRHRARNTR"
     gene            complement(4618..5145)
                     /locus_tag="ACHY1N_004798"
     CDS             complement(4618..5145)
                     /locus_tag="ACHY1N_004798"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage N-6-adenine-methyltransferase"
                     /protein_id="HFS4046952.1"
                     /translation="MTIKSNTPAHDKDCWQTPLWLFDALDIEFGFWLDSAASDKNALC
                     AHWLTEADDALNSEWISHGAIWNNPPYSNIRPWVEKAAEQCIQQRQTVVMLVPEDMSV
                     GWFSKALESVDEVRIITDGRINFIEPSTGLEKKGNSKGSMLLIWRPFISPRRMFTIVS
                     KAALMAIGQGVRRAT"
     gene            complement(5142..5582)
                     /locus_tag="ACHY1N_004799"
     CDS             complement(5142..5582)
                     /locus_tag="ACHY1N_004799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinB"
                     /protein_id="HFS4046953.1"
                     /translation="MKKLTFEIRSPAHQQNAIHAVQQILPDPTKPIVVTIQERNRSLD
                     QNRKLWACLGDVSRQVEWHGRWLDAESWKCVFTAALKQQDVVPNLAGNGFVVIGQPTS
                     RMRVSEFAELLELIQAFGTERGVKWSDEARLALEWKARWGDRAA"
     gene            complement(5656..5946)
                     /locus_tag="ACHY1N_004800"
     CDS             complement(5656..5946)
                     /locus_tag="ACHY1N_004800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein ren"
                     /protein_id="HFS4046954.1"
                     /translation="MTGKEAIIHYLGTHNSFCAPDVAALTGATVTSINQAAAKMARAG
                     LLVIEGKVWRTVYYRFATREEREGKMSTNLIFKECRQSAAMKRVLAVYGVKR"
     gene            complement(5943..6644)
                     /locus_tag="ACHY1N_004801"
     CDS             complement(5943..6644)
                     /locus_tag="ACHY1N_004801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein P"
                     /protein_id="HFS4046955.1"
                     /translation="MKNIAAQMVNFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVF
                     SQLLATFPASLANRDQNELNEIRRQWVLAFRENGITTMEQVNAGMRVARRQNRPFLPS
                     PGQFVAWCREEASVIAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNL
                     YQNMRANALTDAELRRKAADELSCMTARINRGEAIPEPVKQLPVMGGRPLNRAQALAK
                     IAEIKAKFGLKGASV"
     gene            complement(6641..>7192)
                     /locus_tag="ACHY1N_004802"
     CDS             complement(6641..>7192)
                     /locus_tag="ACHY1N_004802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication protein O"
                     /protein_id="HFS4046956.1"
                     /translation="IPQNEGKSPKTRDKTSLKLGDCYPSKQGNTKDTNTKENRKDYSS
                     ENSGESSDQPENDLSVVKPDAAIQSGSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFA
                     GWANDIRLMRERDGRNHRDMCVLFRWACQDNFWSGNVLSPAKLRDKWTQLEINRNKQQ
                     AVVTASKPKLDLTNTDWIYGVDL"
BASE COUNT         1863 a         1786 c         1493 g         2050 t
ORIGIN      
        1 ttttttataa atggcttatc atagaagcat gataccgata aaaatcgccc ataagatctt
       61 atcgaaattg taaccgccag cgcaatcgct gctgacagta gcaaaagagg tacctgaatc
      121 ttctgtctca atatagaaaa ctcaataatt gccggcacaa acaataattc cacagcaaaa
      181 taaaggcgaa atacatttag ctcttgcata gaatgttttc ttttcactgc gaaaaagaat
      241 acaacaccaa taccccaacc gataagaaat atagcaatga cgataactgc aaaaaataaa
      301 cttctggcaa catcatcaac acctgcacct acaatccacc atgggaagcc gtagtaaaaa
      361 gaagtacccc atccatagaa ataagcactc ccccatccaa ggcatcccat gtaggcaata
      421 aaaagtgaag aactcctgag cagcgcacca tccttcataa ccaccccaat acaagatgat
      481 aacattggct tacaactcat aacaaaagca attcaatgcc gtcaagaggt tacaggctaa
      541 aaaaactcta ttacatagca gccagcatgt ttaccgtaca agtacaactc agggcataaa
      601 aaaaacccac tcggcagcgg gtttatacat tttttacaac ataccaaatt tgcatgaagt
      661 atatggcttt taatccagtt ttgcaatatt ttgctgtaaa aatgctgcct tttgttttga
      721 acgtgttctc gtcacaagca ataaagcatc actatcaagc tgtagaaaaa tgtgcttcat
      781 tgcaacccag cgttcagtaa atgtctcgga ccagtttttt gttgtcactc ccaccaatga
      841 tgccagtgtc tggtattcat aggcctcacg ccctgcaagt tcgctcttca catcctgtgc
      901 agccagccag attaacgtct tcaggcgatc cagtgtctta cctgcaattt ttctgttact
      961 taacaaatct ttaaactcgc tccatgccca ttgcgttatg gtgacctgat gcccccatcg
     1021 aacgctttcg ctgtaacacc aaagcaacca tgctttctga tgttcatcga gagacaaaac
     1081 cgcgcggcgc catgaagagg ttgagaattc aaccgggctg accaaagcaa tggatgaacc
     1141 ttttgcgtac gactgcttac cggaagtcgg cgtattatcc agcgtaatca tcttgccagt
     1201 taccacatcc agaatgcgcg gcttctttcg tttgtatgta ccagtatcaa attgtgcatg
     1261 ctcctgccag gcttcgagct ggcctttcgt tgctccgttc aagtcagcag tagctgccat
     1321 aagttgctca cgaacatact gtaaatattg ggtattcatg cagtaaatcc tttctatatt
     1381 ttggcataat tcttcaacat tcggtaatcg ttcaaaaccg aatcggggaa acgacataag
     1441 cacaggagcc cccagcgaca gcgaaggagt tctgatatat aagactcaga catcattcat
     1501 tccccggttc tccaatatct gtttcactca tcatccataa ctacctgtaa ttgccccccc
     1561 tttttttgta acagttctta tattgctata tagaatagcc attactaatg catttaaatt
     1621 taataaaata aaaattataa aaaacataaa acaccacgta aacacactta ataaaaacac
     1681 cgttacatta aaagataata aaaaccgcaa taaaaaaaga ataaatcaat tgtctcacgc
     1741 aattataaaa catcatattg attacgcacc ttgtattaca aactcatgta tgtaaaatac
     1801 gcgcaccatt caaaaaaaag gaagacaata acatatgaaa aaaagtgtca tcgctggcgt
     1861 ctttattgct ctgtcattta ccacgtgttc agctatcgcg aacagccttg cattatcatt
     1921 agcaaatgat gatgcaggga agtttcaacc aatacttaat gatatttatg gcaataaaca
     1981 tgaaaacaga gatgattact cacaaggctt atttctggga tatagccacg atatctcaga
     2041 ctcgagccaa ttatctctcc atattgcgca agatatttac tctccatcag gcagtaataa
     2101 aagacacaac acagctgtaa ctggagacag agcttttagt gcatacactc acactggtat
     2161 tgaatggaac tcccttgcga atgactggat tcgctatcga ttaggtactg acataggtgt
     2221 tgttggcccc gacgcaggcg gtcagaaagt acaaaataaa gctcatgaga ttattggggc
     2281 agaaaaatat catgcatggg atgatcaaat agagaatcgc tacggttata ctgtaaaagg
     2341 gatgctatcc atgacaccaa gtatggatat tttaggtgct aatgttggat tataccctga
     2401 agtttctgct gttactggaa acttatttca atatgtagca tatggcgcaa ccattgccat
     2461 tggtaatgat aaaaccttca attcggataa tggctttggt ctgctggctc cccgtggttt
     2521 aatgcatatg tccgatacaa gcggattcaa atacaagatt tttgcaggta tggaaagacg
     2581 agatgtcaat cgcaactata ctctcgaagg aaaaacaata cagacgaaac aaacaacagt
     2641 atcgctaaac aaaactgttg atgaatatca agttggcgca acaattgggt atgcacctgt
     2701 agccttcaca ctagcattta ataaagtaac atcagaattc aagacagggg atgactattc
     2761 atttataaat ggagcaatca ccttcttttt ttaactgaat tgaattcaat caaaataaca
     2821 taagtccaac aaaaacataa agtgcgaaat gaatgccagc tccatttatt tcgcactata
     2881 aaagattaaa agttgcaata aaataataaa atgactcagt tacgaaaacc aataaactgt
     2941 ggccagtagt gagtcgctca tcatcgggct ttttggcgaa tgaaatttag ctacgctttc
     3001 gagtctcatg cgccttctcc ctgtacctga atcaatgtga ggtttccgca gaacactgcg
     3061 ccagtatcga tatacatctg gttggcaaat ttgagtggtt tcactgctgg cgtatgacca
     3121 aagatgaacg tgtccgcgcc tttgatttct ttcacgatcc cgtcttgtga gttgctgatt
     3181 cgttcgcggt tccagattac ctgctgatga tcaactggct ttccaaactc gtatttatca
     3241 caaggataat cggcgtggca aatgacatat tttttatctt tgctcaccag ttcgatgatt
     3301 aacggaagtt cttctgcttt atgggcaaga actttagcca gagtctcttt gtcgtaatcg
     3361 agattaaaga accagccacc gccattaagc agccagtgat taacgtttcc acgctctgat
     3421 aagccatcaa tcatcatttg ctcatggttt ccacgcacag ctctgaacca ggggaatgtg
     3481 attaattcca gacattcgac gttctctgta ccgcgatcaa ccaaatcgcc aaccgagatg
     3541 agcaggtctt ttttggtgtc gaatccaatc gtatccagtt tgttcatcag gttcgtgtag
     3601 catccgtgca ggtcgccagc tacccaaata tttcggtatt tgctgccatc aattctttcg
     3661 tagatattca tgcagcctca cttctgctgt ttcgcaggtc tttgagtttc tgttggtact
     3721 ctgccttgat cgccttgcac tcttcgacag tccagcgatg gcggttatgg tttgattcga
     3781 tttcgtctac tgcttcctgc ccgatgcggc taatcagttc gacgcgatac ggaacgagat
     3841 ttccgctttt gtgctggttg cacaccacgc attgcttgtg aatattgcgt tcatcaaatc
     3901 ggagttgagg tgccgcagca gttgtccggt aatgtccggc atcccactga gcagacgtga
     3961 gcgttccgca cgagatacat ggtaagtcgc ggtctctttc tctgatgaag gcgtttacgg
     4021 cttgttgggc ttgtttaatc cagtaactgc ggggctttaa ggcgagtttt cgaatcttaa
     4081 gtttatcttt ctgtttctgc tcctctcgtc gtcgtttctt ctctgctgct ttttccgctt
     4141 tttcgcgttc tttacttcgt cgttcgagtg ctatcttggt tccacactct ggagagcacc
     4201 accactgatt agcgaatgca gggtgaaacc attcccgaca ttcatcgttt ttacatcgtc
     4261 ttcgcgctgg tttagccatc atcttcttcc tcgtgcatcg agctattcga atcgctcatc
     4321 agctctgcac agcagtgctc acacacgtga acttccagca catgcagctt ctgaccgcaa
     4381 ttagcgcacg ttaaagcccg ctcgacgctt tcttgttcgt aacttcgatt tgggtcaatc
     4441 accttgtatt cctcgcacga tgtcttagcc accggatatc ccacaggtga gccgtgtagt
     4501 tgaaggtttt tacgtcagat tcttttggga ttggcttgcg tttatttctg gagcgtttcg
     4561 ttggaaggta tttgcagttt tcgcagatga tgtcggtgaa acttcgtcgt tgtcgcctca
     4621 tgtcgccctc ctgacgccct gcccgatcgc catcaatgcc gctttggata cgatagtaaa
     4681 catccgtcga ggactaatga acggtcgcca aatcagcagc atggagcctt tgctgtttcc
     4741 cttcttctcc agccctgtcg atggttcgat aaaattaatc cgtccatcag tgataatacg
     4801 aacttcgtca acactctcca gagccttgct gaaccatccg acagacatat cctctggcac
     4861 aagcatcact accgtctgtc gctgttgtat gcactgctca gcggcttttt ccacccacgg
     4921 cctgatattg ctgtacggtg ggttattcca gattgcaccg tggcttatcc actcagaatt
     4981 tagcgcgtcg tcagcctcag ttagccagtg agcgcacaga gcgtttttgt cgctcgctgc
     5041 cgaatccagc cagaatccaa actcaatatc cagtgcatca aaaagccaaa gcggcgtttg
     5101 ccagcagtcc ttgtcgtgtg ctggcgtatt tgatttgata gtcatgcagc ccgatctccc
     5161 catcgcgctt tccattcgag agccagtcgc gcttcgtctg accacttaac gccacgctct
     5221 gtaccgaatg cctgtataag ctctaatagc tccgcaaatt cgcttacacg catcctgctg
     5281 gttggctggc ctattaccac aaagccattc ccggcaaggt taggaacaac atcctgctgc
     5341 tttaatgctg cggtaaacac acacttccag ctttctgcat ccagccagcg accatgccat
     5401 tcaacctgac gagagacgtc acctaagcag gcccatagct tcctgttttg gtctaagctg
     5461 cggttgcgtt cctgaatggt tactacgatt ggtttggttg ggtctggaag gatttgctgt
     5521 actgcgtgaa tagcgttttg ctgatgtgct ggagatcgaa tttcaaaggt tagttttttc
     5581 atgacttccc tctcccccaa ataaaaaggc ctgcgattac cagcaggcct gttattagct
     5641 cagtgatgta gatggtcatc ttttaactcc atataccgcc aatacccgtt tcatcgcggc
     5701 actctggcga cactccttaa aaatcaggtt cgtgctcatc tttccttccc gttcttccct
     5761 agtagcgaac cggtaataca ccgttcgcca gaccttacct tcgataacca gaagacctgc
     5821 ccgtgccatt ttagccgcgg cctgatttat gctggttact gttgcgcctg ttaacgcggc
     5881 aacgtccggc gcacagaagc tattatgcgt ccccaggtaa tgaataattg cctctttgcc
     5941 cgtcatacac ttgctccttt cagcccaaac ttagctttga tttctgcgat cttcgccaga
     6001 gcctgtgcac gatttagagg tctaccgccc atgacaggaa gttgttttac tggttcaggt
     6061 atagcctcac cacggttaat tcgtgcggtc atacaggaca gttcatcggc agccttgcgc
     6121 cgtaattccg catcagtaag cgcattggcc cgcatgttct gatacaggtt ggtaaccagc
     6181 cagtagtgcg cgtttgattt ccacggataa gactccgcat ccggatacag gcctcgcttc
     6241 cggcaatact cgtaaaccat atcaaccagc tcgctgacgt ttggcagtcc ggcgataacg
     6301 gatgcttctt cccggcacca tgcaacaaac tgcccgggtg atggcagaaa tggtcgattc
     6361 tgccgacggg ctacgcgcat tcctgcgtta acctgttcca ttgtggtgat cccgttttcc
     6421 cggaaagcca gaacccactg gcggcggatt tcgttcagtt cgttctggtc acggttagcc
     6481 aggctcgccg ggaaagttgc cagtaactgg ctgaacacac cgttgatgat ctgcgctacc
     6541 tgctgtacct gaggcttttc gtcgtactgt tccggcatgt tgttggcgat ccgacgcatc
     6601 tgctcacggt caaagttaac catctgtgcg gcgatgtttt tcataaatcc accccgtaaa
     6661 tccagtctgt gtttgtcagg tcgagttttg gtttactggc tgtcacgact gcctgttgct
     6721 tgttacggtt gatttcgagc tgggtccact tgtcgcggag tttggccggg ctcagcacat
     6781 taccggacca gaagttgtcc tggcaggccc agcggaacag cacacacata tcgcggtggt
     6841 tacgtccgtc acgttcacgc atcaggcgga tatcgttagc ccaccctgca aaattcggtt
     6901 ttctggctga tggcgcgata gtcttcacca tgtcaaacat ccactctgcg gcggtcaggt
     6961 cttctgctgt cccccatttg ctgccgctct gaattgcagc atcaggtttc accacagaaa
     7021 ggtcgttttc tggctggtca gaggattcgc cagaattctc tgacgaataa tcttttctat
     7081 tttcttttgt attagtgtct tttgtgttcc cctgttttga gggatagcaa tcccccaatt
     7141 tgagggatgt tttatccctc gttttagggg attttccctc gttttgaggg at
//
LOCUS       DAZUDJ010000140         6995 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.142, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000140 DAZUDJ010000000
VERSION     DAZUDJ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6995
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.142"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(203..625)
                     /locus_tag="ACHY1N_004803"
     CDS             complement(203..625)
                     /locus_tag="ACHY1N_004803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="HFS4046957.1"
                     /translation="MRSAAARLLLIPLITATIALTGCTPKTSLERHTRHYVYASDDGF
                     DPNFYTQKADTIRMMLPFFQQFRDMGMKDKAAGVSAETAQQRVKEFHSEKFFHSLRST
                     TAFAGRKYTNSDMPSPKKMKLMADTISAVYLDGYEGRQ"
     gene            747..1025
                     /locus_tag="ACHY1N_004804"
     CDS             747..1025
                     /locus_tag="ACHY1N_004804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046958.1"
                     /translation="MKKCVPVLLFSVLSASVASHADSNVFQQKAEKTKNGIVADVNAR
                     QKMFSNRLKIQLQIDELRAELAGTRDAQKREDLRKKLESLERQKKSLR"
     gene            complement(1017..1307)
                     /locus_tag="ACHY1N_004805"
     CDS             complement(1017..1307)
                     /locus_tag="ACHY1N_004805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001672407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046959.1"
                     /translation="MSKSPRHKLNKTDKRLLDTLVAAGYEHDKARDLIQKQVYTLTLA
                     DQRHVVSEISNGVNPTQAYSAVYQARRIRLARKYLNGKKVMEETGENTPPSA"
     gene            1548..3200
                     /gene="cka"
                     /locus_tag="ACHY1N_004806"
     CDS             1548..3200
                     /gene="cka"
                     /locus_tag="ACHY1N_004806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_159420795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pore-forming bacteriocin colicin K"
                     /protein_id="HFS4046960.1"
                     /translation="MAKELSGYGPTAGESMGGTGANLNQQGGNNNSNSNSGVHWGGGS
                     GHGNNGGQGNSNSSGSTSTVMKTGESYLTPWGDVVINNDGLPVMNGIVMTEENSTLVD
                     NPFGGVSRVLNSLISDMPSLFAESSGNNNNNTASVNTAPTNAQVSDMDKSSKVVSNVI
                     NEKQKQKNKIATQISEKQKKIEEMKKVFKHHSYHGITDLERDVDELQKKSNQLDADIS
                     KLNSYKNTLQSKIGDVNKQKEAEEKARENAEVAEHETLNEEKQAVAEAEKRLAEAKAE
                     LAKAESDVQSKQATVSRVAGELENAQKSVDVKVTGFPGWRDVQKKLQRQLEAKQAEYS
                     AVENELKNAVSFRDGKAAEVKEAEQKLKEAQDALEKSQIKDAVDTMVGFYQYITEQYG
                     EKYAKIAQDLAEKSKGKKIQGVDEALAAFEKYKNVLDKKFSKVDRDAIFNALESVNYD
                     ELSKNLTKISKSLKITSRVSFLYDVGSDFKNAIETGNWRPLFVTLEKSAVDVGVAKIV
                     ALMFSFIVGVPLGFWGIAIVTGIVSSYIGDDELSKLNELLGI"
     gene            complement(3197..3487)
                     /gene="cki"
                     /locus_tag="ACHY1N_004807"
     CDS             complement(3197..3487)
                     /gene="cki"
                     /locus_tag="ACHY1N_004807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011264161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin K immunity protein"
                     /protein_id="HFS4046961.1"
                     /translation="MHLKYYLHNLPESLIPWILILIFNDNDNTPLLFIFISSIHVLLY
                     PYSKLTISRYIKENTKLKKEPWYLCKLSALFYLLMAIPVGLPSFIYYTLKRN"
     gene            3517..3648
                     /locus_tag="ACHY1N_004808"
     CDS             3517..3648
                     /locus_tag="ACHY1N_004808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_072023513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="HFS4046962.1"
                     /translation="MKIIIFLITILFLSGCQANYIRDVQGGTVAPSSSSELTGIAVQ"
     gene            complement(3843..3986)
                     /locus_tag="ACHY1N_004809"
     CDS             complement(3843..3986)
                     /locus_tag="ACHY1N_004809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001422066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFS4046963.1"
                     /translation="MHEPPVQPDRCALSGNYRLESNPVRHDLTPLAAAIGNWIVDLDT
                     QNS"
     gene            complement(4654..4845)
                     /locus_tag="ACHY1N_004810"
     CDS             complement(4654..4845)
                     /locus_tag="ACHY1N_004810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="HFS4046964.1"
                     /translation="MTKQEKTALNMARFIRSQTLTLLEKLNELDADDQADICEALHDH
                     ADELYRSCLARFGDDGENL"
     gene            4913..5236
                     /locus_tag="ACHY1N_004811"
     CDS             4913..5236
                     /locus_tag="ACHY1N_004811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFS4046965.1"
                     /translation="MLTIRVTDEEHARLLARCEGKQLASWMRKVCLGAPPSKTSGLPT
                     LAPPLLRQFASVGNNLNQIARKINSGQWSGHDRVHVVAALMAIGRELSELRDEVRKQG
                     ERDDS"
     gene            5445..5879
                     /locus_tag="ACHY1N_004812"
                     /pseudo
     CDS             5445..5879
                     /locus_tag="ACHY1N_004812"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            5914..6474
                     /locus_tag="ACHY1N_004813"
     CDS             5914..6474
                     /locus_tag="ACHY1N_004813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="HFS4046966.1"
                     /translation="MSNLLQMGTDFEKKLKERAVSTENMLNSEFRKLEASVDRELNLN
                     GQKIRDAISAHTAAVKEQLETLNSAVNAQFSATENELARRQEELLWKLVKGRILYPSL
                     TALCVTGGIFLASWGLIQWQESRIAANILAIRDQEETLAKLREKTWGVTYHEGRNGKF
                     LVLPSGVKGENNWTVEKKNAVRLVRE"
     gene            6481..6714
                     /locus_tag="ACHY1N_004814"
     CDS             6481..6714
                     /locus_tag="ACHY1N_004814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="HFS4046967.1"
                     /translation="MTELEMHLLNALEQLQQDYMQRLKDWESAFTDLQHMFELTRQEN
                     GQLREQCDDLSQQVQRLAGQVDHLSRLFITNSR"
BASE COUNT         1886 a         1387 c         1937 g         1785 t
ORIGIN      
        1 aaaaaaaaca gtgtcatgag gtttacgcag gcaaaaccag cgttattcac atggctgaat
       61 agctatgcat acggttaaaa tttatcaggt gcgatcgcgg cagcttttcg ggtggtttgt
      121 tgccattttt acctgtcagc agccgtgatc gcgctgaacg catttcagcg gtgcgtacaa
      181 ttaagggatt atggtaaatc ccttactgtc tgccctcgta tccatcgaga taaaccgcag
      241 aaatggtgtc tgccattagt ttcatttttt tcggcgaagg catatcgctg tttgtgtatt
      301 ttctgccagc aaaggctgtt gtgctccgga gtgagtgaaa aaatttttct gagtggaatt
      361 cttttacacg ttgctgtgcc gtttctgctg atactccggc tgctttgtct ttcatcccca
      421 tatcccggaa ctgctgaaag aacgggagca tcatacgtat ggtgtctgct ttctgggtgt
      481 agaagttagg atcaaatcca tcatctgaag cataaacata atgccgggta tgtcgttcca
      541 ggctggtctt tggtgtgcat cctgtaagag ctattgttgc tgttatcaga ggtatcagaa
      601 gcagcctggc agcggcagat ctcataaaca tctccttgcg tttttaatct tgatactcag
      661 ggagttatat ctccgaagag tatctcttat catacgtcgg tttactccca atgtgatttg
      721 atggtcaatg agtcaggaat aatcccgtga aaaaatgtgt gccagtcctg ctttttagtg
      781 ttctttctgc ttcggttgcc agtcatgcgg acagcaatgt ttttcaacaa aaggccgaga
      841 agacaaaaaa cggcattgtt gcggatgtta atgccagaca gaaaatgttc agtaatagac
      901 tgaagataca acttcagatc gatgagttga gagcagagct ggctggcacc agagatgccc
      961 aaaaaagaga ggatttgcgt aaaaaactgg agtctctgga gcggcaaaag aaatccttac
     1021 gctgatgggg gcgtattttc cccggtttct tccataacct ttttaccgtt cagatattta
     1081 cgggcgaggc gaatgcgtct tgcctggtat accgccgagt aagcctgggt gggattcaca
     1141 ccattactga tttcactgac cacatgacgc tgatcagcca gtgtcagcgt gtaaacctgt
     1201 ttctggatga ggtcacgggc tttgtcatgc tcatatccgg cagcaacaag ggtgtcgaga
     1261 agtcgtttgt ctgttttgtt cagtttatgg cggggtgatt tgctcacatc gttctccgtt
     1321 ttttcatgat ccaacagttt tatatctcat cctgatttgc tccggtgttc tgtttcgacg
     1381 ttctcaatgc ctgcctcccc atagtgtgat ccttattgca aaaatgaaaa tccatgctct
     1441 tgacatggac aatgctgagt agtaggtttt tactgtatat aaaaccagtg gttatatgta
     1501 cagtatattg tttttaattt attgttttaa ttatcaaaga ggaatttatg gctaaagaac
     1561 taagtggata tggaccaact gctggtgagt ctatgggggg aacaggggcg aatctgaatc
     1621 agcaaggtgg aaataataat agtaatagta atagtggggt tcactggggt ggtggctctg
     1681 ggcatggtaa taatggtggt caggggaatt caaattcatc tggttctaca tcaactgtga
     1741 tgaaaaccgg tgagtcatat ctgactccgt ggggtgatgt tgtcattaat aatgatggcc
     1801 ttccggtgat gaatggtatt gttatgacag aagagaattc aactctggtt gataatccat
     1861 ttggaggggt ctccagagtt cttaattctt taattagtga tatgccatca ctttttgcag
     1921 aaagctcagg aaataacaac aataacactg cttcagttaa tactgcacca acgaatgctc
     1981 aggtcagtga tatggataag agttcgaagg tggtgagtaa tgtaattaat gaaaaacaaa
     2041 agcagaagaa taaaattgct acacagatta gtgaaaaaca gaagaaaatc gaggagatga
     2101 aaaaagtatt caagcatcat tcttatcatg gtatcactga tcttgagagg gatgttgatg
     2161 agttgcaaaa aaaatcaaat cagcttgatg cagatattag caaacttaat tcttataaaa
     2221 atacattgca aagtaaaatt ggtgatgtga ataaacagaa ggaagctgaa gaaaaggctc
     2281 gtgaaaatgc agaggtcgct gaacatgaaa ctcttaatga agagaaacag gcggtggcgg
     2341 aagcagagaa gcgtttagct gaggcgaaag ctgaactggc gaaggctgaa agtgatgtac
     2401 agagtaagca agctactgtt tccagagttg caggagagct tgaaaacgct cagaagagtg
     2461 ttgacgtgaa ggtcaccgga tttccgggat ggcgtgacgt tcagaaaaaa ctacagcgtc
     2521 agcttgaagc taagcaggct gagtactccg cagttgaaaa tgaacttaag aatgctgtta
     2581 gtttcaggga tggtaaggcc gctgaggtta aagaggcaga gcagaaatta aaagaagctc
     2641 aggatgctct tgaaaagagc cagataaaag atgctgttga tactatggtt ggattttatc
     2701 aatatataac cgaacaatat ggagaaaaat acgcaaaaat tgctcaggat ttagcggaaa
     2761 agtctaaagg aaagaaaatt caaggtgttg atgaagctct ggcagcattt gaaaagtata
     2821 agaatgtact ggataagaaa ttcagtaagg ttgatcggga tgctattttt aatgcgttag
     2881 agtctgttaa ttatgatgag ttatctaaga atttaacgaa gatatcaaag tcgcttaaaa
     2941 tcaccagtcg agtatctttt ctatatgatg ttggttctga ttttaaaaat gcaatagaaa
     3001 ctggtaactg gcgacctttg tttgtcacgc tggagaaaag tgcggtcgat gtaggtgtgg
     3061 caaaaattgt ggcattaatg tttagtttta ttgttggtgt gcctcttggt ttctggggga
     3121 ttgcaattgt cacaggtatt gtttcttctt acatagggga tgatgagttg agcaaactta
     3181 atgagttgtt agggatttaa tttctcttta gagtgtaata tatgaaactt ggcaatccta
     3241 ctgggattgc cattaataaa taaaacaatg cagataactt gcataagtac cagggttctt
     3301 tttttaactt tgtattttct ttgatatatc tagatatggt taatttagag tatggatata
     3361 gcaatacatg tattgatgat ataaatataa ataacaaagg agtgttatca ttgtcgttaa
     3421 atattaaaat aagaatccat ggtataagtg attcaggtaa attatgtagg tagtatttta
     3481 aatgcataag tatttttact tttgttggaa agaaatatga aaataataat ttttctaatt
     3541 acaatattat tcttgtcagg atgtcaagca aactatattc gtgatgtaca aggaggaacc
     3601 gttgcaccat cttcgtcttc tgaactgacg gggatcgcgg ttcagtagaa aagatcaaag
     3661 gatcttcttg agatcctttt tttctgcgcg taatctgctg cctgtaaacg aaaaaaccgc
     3721 ctggggaggc ggtttagtcg aaggttaagt cagttgggga ctgcttaacc gggtaactgg
     3781 ctttagtgga gcacagatac caaatgctgt ccttccagtg tagccgctat aaggcttcaa
     3841 cttcaagagt tctgcgtatc taaatccact atccagttac caatggctgc tgccagtggc
     3901 gttaagtcgt gtcttaccgg gttggactca agacgatagt taccggataa ggcgcagcgg
     3961 tcgggctgaa cggggggttc gtgcacacag cccagcttgg agcgaacgac ctacaccgaa
     4021 ctgagatacc aacagcgtga gctatgagaa agcgccacgc ttcccaaagg gagaaaggcg
     4081 gacaggtatc cggtaagcgg cagggtcgga acaggagagc gcacgaggga gccaccaggg
     4141 ggaaacgcct ggtatcttta agtcctgtcg ggtttcgcca cctctgactt gagcgtcggt
     4201 ttttgtgatg ctcgtcaggg gggcggagcc tatggaaaaa cgccagctgc gtggcctttt
     4261 ccgggttctt gttttttgct cacatgtttc ttttggtgtt atcccctgat tctgtggata
     4321 accgcattac cgtctttgag tgagctgata ccgctcgccg cagccgaacg accgagcgga
     4381 gcgagtcagt gagcgaggaa gcggaaaagc gcctggacga gcattttctc cttacgcatc
     4441 tgtgcggcat ttcacacccg gcatggtgca cttttcatac aatcctcact gatgccaaat
     4501 gattaagcca gtatacactc cgctatcgct acgtgactgg gtcatggctg cgccccgaca
     4561 cccgctaaaa cccgctgacg cgccctgacg ggcttgtctg ctcccggcat ccgctcacag
     4621 gccagctgtg accgtctccg ggagctgcat gtgtcagagg ttttcaccgt catccccgaa
     4681 gcgtgcgagg cagctgcggt aaagctcgtc agcgtgatcg tgaagcgctt cgcagatgtc
     4741 agcctggtcg tcggcgtcca gttcattcag tttttccagc agggtcagcg tctggcttct
     4801 gatgaagcgg gccatgttaa gggcggtttt ttcctgttta gtcacagttc tgtttctcca
     4861 tgtgtgggga gtctgtcgga ggtttttaat gataccggtg aaacgcgaaa ggatgctcac
     4921 gatacgggtc acggatgagg aacatgcgcg gctgctggca cgttgtgagg gaaaacaact
     4981 tgcgtcatgg atgcgtaagg tctgcctggg ggcaccgcca tcgaaaacgt caggtcttcc
     5041 gacactggca ccgccgctgt tgcgccagtt cgcttcggtc ggcaataacc tgaatcagat
     5101 agcccggaag ataaacagcg gacagtggtc ggggcatgac cgggttcatg tggtggctgc
     5161 actgatggcc atcggacgtg aactgagtga gctgagggat gaggtccgta aacagggaga
     5221 acgggatgat agttaagttt catgccaggg gaaaaggcgg tggcagtggt ccggttgatt
     5281 acctgctggg ccgggagcgt aaccgggaag gggcgagagt tctgcggggt gctcccgaag
     5341 aggtgcggga actcatcgat gccacgccgt ttgcgaaaaa atacacctcg ggggttctgt
     5401 cttttgcaga gcagaccctg ccaccgggag agcgtgaaag ggtgatggag agctttgagc
     5461 gggtactgat gcccggtctt gaaaaaaatc agtacagcat cctgtgggtg gagcaccagg
     5521 acaaggggcg tcttgagctg aattttgtca tcccaaatat ggagctggcg agcggaaaac
     5581 ggctccagcc ctattacgac cgagcggacc gtccgcgaat caatgcctgg cagacactgg
     5641 tgaatcacca ttacgggctg cacgacccga acgcaccgga gaacaggcgg acacttgtca
     5701 ccccgaataa tctgccgaaa gcgaaacagg aggccgcaga agcgattacg aggggactgg
     5761 aggctcttta ccatgccgga gcgctaaaaa cgcgtcagga tgtcactgag gcgcttacag
     5821 cggcaggttt tgaggttgtg aggacaacca ggagcagtat cagtatcgcc gacccggagg
     5881 gtgggcgtaa tctcaggctg aaaggggcgc tgtatgagca atcttttaca aatggggaca
     5941 gacttcgaga agaaactgaa agagcgtgcc gtctctacag agaacatgct gaacagcgag
     6001 ttcaggaagc tcgaagcgtc tgtagacagg gaactgaact taaacgggca gaaaatcaga
     6061 gacgctatca gcgcacacac agcagcggtg aaagaacaac tggagacgct gaacagtgcc
     6121 gtgaacgcgc agttcagcgc cacagagaac gaactggccc ggcggcagga agagctgctc
     6181 tggaagctgg tcaaagggcg gatactgtac ccgtcgctga cggcgctttg cgtcacgggc
     6241 gggatttttc tggcgtcatg ggggctgatt cagtggcagg aaagccggat tgcggcgaac
     6301 atcctggcta tcagggacca ggaagagacg ctggcgaaac tccgggaaaa aacatggggt
     6361 gtgacgtatc acgagggcag gaacgggaaa tttctagtgt tgccgtccgg ggtgaagggg
     6421 gaaaacaact ggacggtgga gaagaagaac gcagtaagac tggtcaggga gtaagtgagt
     6481 atgacagagc tggaaatgca cttactgaac gccttagagc aattgcagca ggactatatg
     6541 cagcggctga aagactggga gagcgccttc acggatttgc agcatatgtt cgagctgaca
     6601 cgacaggaga acgggcaact gagggaacag tgcgacgact tgagtcagca ggtgcagaga
     6661 ttagccgggc aggtggacca cttgagtcgg ttatttatca cgaacagcag ataagggatg
     6721 aacaggaaag gcaggcacgc ctggaacggg agcgtgcgcg gtcctggcat gaagagcagg
     6781 aacgggaagc acgggtatgg cgtggcccgt caataggtat gtgacggtga gttgttccgg
     6841 gaggttgcca gatggtaccg gaacgcgtta aaaacgcatc cgggcgcgat tctggcgtgt
     6901 cgtttttgtt gctgtgtttt gcctctttgc cagatcgcgc tcattcctca gcctcatccc
     6961 gcgatgtctg cgtatgtcat caactgaaaa gatgg
//
LOCUS       DAZUDJ010000141         6955 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.143, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000141 DAZUDJ010000000
VERSION     DAZUDJ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6955
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.143"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..6363
                     /gene="efa1"
                     /locus_tag="ACHY1N_004815"
     CDS             <1..6363
                     /gene="efa1"
                     /locus_tag="ACHY1N_004815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001239084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lymphostatin Efa1/LifA"
                     /protein_id="HFS4046968.1"
                     /translation="SGNTEKDSHYDRLLDAFFKKHNENIHNKIQRIKDEFKEYSRVTI
                     HNIDKVIFKGQTLDRLYHEGYVFSDINTLSRYTLHGLGITGVHTEENLLPAPSSSLIN
                     ILKEHYNEDEISAKLPLAYDYILNKKESSSIPVEILNKLSELPPHELLTPVLGQSVNP
                     LGMGYSSDNGKITEQVIVSGADGFDNPISGLIYTYLEDLYNIHVRMREGTLNSQNLRQ
                     LLENSVSSCFLTEQSINKLLSEAEKRPYQSLTEIHQHLTGLPTIADATLSLLSVGLPG
                     TGKLLRREQDYGRPPVTAIQDSTFVLPYNFKGIGFNDNIISSAPVVSSLHFIAEHAKY
                     TLLSWPEFYRHHAQRWFEMAKGYGSQNIDFHPQSLLVTQEGRCMGLALLYLQTEDTAH
                     YSILQENLMTVSALHQTSNRDKLPLSKDDNSLMTRTYSLIEMLQYQGNKYITNESLLH
                     KTAWNQERITLLFNEKGVKRALISTPNHTLVLQQLEDIYRLTDPNFGHADFLSPIDAL
                     KFIEAMIQLTPTLQEYYGLLNKDINKHIQVHYAESDMVWNKLLPENDAGLSTRIQHTT
                     TDRLANLAEPVAVAGISLPVKTLYDIGATLDGRRITSPPTSEQIPSLRLNGDVLNDYL
                     SRTVLTPEQADNIRKILHTQGIRSGTRPIDPEMIRGTQDDLVSSQTRLQRQATRVKQQ
                     LAGVLDTLQQHFQNIPRSSGRHLSVENIELADIGSGRFNLQIRDGETLHTTSVEVPEV
                     VSRFQKLSTMLSALPASGIMDFDLGMSVVGVVQYARLLQQGHEDSTLAKINLAMDIKQ
                     LSEATLGSMIQIAGNKFLNTEGIQGFRLESAVAEGMRSVATRTGGTMGKALSASARVL
                     ELPVLETVLGTWNLYNSVIQLQQATSYSETMAARVQIAFDSISLGLTAASVAFPPLII
                     ATGPIAAIGMGASSIARNVARKEERHTQWLEYKKFLTDGSKHIVVASPERGLLDFSGN
                     KVFGKMVLDLRQSPPLLHGESSFNADRKIGHRPDLGDWQIREKVGYANSISPYSSLAH
                     GYANSKWPQTIPKIPSGEYDTIILGYGHQYQANTEIEYLSNWIVWREAVPDSTSRHKR
                     PPLEVLNSQCTVIAGERKTTVLPLRVLSDLTPECTEQAISLKDYKFILRGGSGGLAVQ
                     VGGAGYYDIDANPVAKENTLSFRGLPEEFPLAFDLSKQTQSVMLKTTDGEVPVMTITQ
                     KGINTLVGTTAGENWLTGNDKDNTFHTSSGGGTVISGGGNNRYIIPRDLKTPLTLTLS
                     NSSVSHEILLPETTLTELKPVAFELSLIYWAGNNIKVQLEDETQLNRFAGNFRGHTSD
                     GITLEAVSQENGIQLGVSSCDVQRWQAVYPEENNRPDAILDRLHDMGWSLAPEVRFRG
                     GETSASYDPLNRQLVYRLQEHYSEFRLTGSRHYTTAVTGTPGSRYIITGPDTAQISPA
                     QIILAGDNDHPETIDLLEASPVLVEGKKDKNSVILTIATIQYSLQLTISGIDESLPGT
                     TRVAIQPQDTRLLGDVLRILPDNGNWVGIFRSGHTPTVNRLENLMALNQVMTFLPRVS
                     GSAEQVLCLENLGGVRKKVEGELLSGKLKGAWKAEGEPTVPVNISDLSIPPYSRLYLI
                     FEGKNNVLLRSKVHAAPLKITSAGEMQLSERQWQQQEHIIVKPDNEAPSLILSEFRRF
                     TISSDKKFSLKLMCHQGMVRIDRRSLSVRLFYLREQPGIGSLRLTFRDFFTEVMDTTD
                     REILEKELRPILIGDTHRFINAAYKNHLNIQLGDGVLNLADIVAEYARIQKEETSKIL
                     YQYQGAMKKKTDGPSVVEDAIMTTTVTTDSGEPFPTFHPWYTDDLSGRYKSVPMARKA
                     DTLYHLTPKGDLQIIYQVATKMVNQAMIVSLPNYRHEWEKYNLSILSEIPQNNNTVVH
                     SILRVNGPTMQVRTIDYRGTDENNPIVSFSDTTFINGEQMLSYDSHSSGRVYSREEYM
                     MWELQQRVSEASSARTQDYWLMDAAVRNGEWKITPELLRHTPGYIRSTVSKWSRGWLK
                     TGTILQTPEDRNTDVYLTTIQNNVFSRQGGGYQVYYRIDGMAGADIADNAPGETRCTL
                     RPGTCFEVTSVDERHYEWNIIYVTLKTCGWSRNGQSKTPNGDNLFN"
     gene            6535..6885
                     /locus_tag="ACHY1N_004816"
                     /pseudo
     CDS             6535..6885
                     /locus_tag="ACHY1N_004816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015869530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2084 a         1565 c         1581 g         1725 t
ORIGIN      
        1 tcaggaaata cagagaagga ctctcattac gatagacttc ttgatgcttt ttttaaaaaa
       61 cataatgaaa atattcataa taaaatacaa agaataaaag acgagttcaa ggaatactcc
      121 cgtgtaacca ttcataatat agataaagtt atatttaaag ggcaaacact ggatcgtctt
      181 tatcatgaag gatatgtatt ttctgatatc aataccttgt ctcgttatac actacacgga
      241 ctaggaataa ctggtgtaca tactgaagaa aacctgctac cagctccttc atcgtcctta
      301 attaatatat tgaaagaaca ttataatgaa gatgaaatta gtgcgaaatt accactagca
      361 tatgattaca ttttaaataa aaaagaatca agctctattc ctgttgaaat tttgaacaaa
      421 ctttcagagt taccaccaca tgaactactc acacctgttc ttggccagag tgttaatcct
      481 ctgggcatgg gctactcatc cgataatgga aaaatcacag agcaagtaat agtcagtgga
      541 gctgatggat ttgataatcc catatctgga cttatatata cctatcttga agatctatat
      601 aacatccatg taaggatgcg agaaggtaca ctaaattcac agaatcttcg tcagcttctg
      661 gaaaactctg tttcttcatg ctttttgact gagcaaagta ttaataaatt acttagtgag
      721 gcagaaaaaa ggccttatca gtctttaaca gaaatacatc agcatctcac aggattacca
      781 actattgccg atgcaaccct ttcattactt tctgttggat tacctggtac gggaaaacta
      841 ttgcgcaggg agcaggacta tgggcgtcca ccagttacag caattcagga ttccacattt
      901 gtactccctt ataatttcaa aggtattggt tttaacgata acattatatc ctctgcacct
      961 gtagtctcct cattacattt tatcgctgaa catgcgaaat atactttgtt gtcatggcct
     1021 gagttttatc gtcatcatgc acagcgatgg ttcgaaatgg ctaaaggata tggaagccag
     1081 aatattgatt ttcaccctca gtctctattg gtaacccaag aaggacgctg tatgggatta
     1141 gccttacttt atttacagac tgaagatact gctcattata gcattctcca ggaaaaccta
     1201 atgactgtga gtgcacttca tcagaccagt aatcgcgata agttgccact gtccaaagat
     1261 gataattcct taatgacaag aacttatagt ctgattgaaa tgctacagta tcagggaaac
     1321 aaatatatta ccaacgaatc gctactacat aagaccgcat ggaaccaaga aagaataact
     1381 ttattattca atgaaaaagg agttaagcga gccctgataa gcacgcctaa tcatactctg
     1441 gttctgcaac aactggagga tatttaccgg ctcactgatc caaattttgg gcatgcagat
     1501 ttcctttcac ctatagatgc tctgaagttt attgaggcta tgatacaatt aactccaaca
     1561 cttcaggaat attatggcct attaaacaaa gacattaata aacatataca agtacattat
     1621 gccgaatcag atatggtctg gaataagctt ctgccagaaa atgatgctgg actgagcacc
     1681 agaattcagc acaccaccac cgaccgtctg gcgaatctgg ctgaaccagt cgctgttgca
     1741 ggtatctccc tgccagtaaa aacactttat gatatcggag ccacccttga cggtcggcgc
     1801 atcacctctc ctccaacatc ggagcaaatc ccttctctgc gtctcaacgg tgatgttctg
     1861 aatgattatc tgtcccgcac agttctgact ccagaacagg ctgataacat aagaaaaata
     1921 ctgcacactc agggaatacg cagcggtacc cgtcccatag atccggagat gattcgtggg
     1981 acgcaggatg acctagtttc gtcacagact cgtctgcaaa ggcaagcaac acgggttaaa
     2041 cagcaactcg ccggtgtact tgatactctg caacagcact tccagaacat tccacgttca
     2101 tccggtcgtc atctttctgt agagaatatt gagctggctg atatcggaag tgggcgtttc
     2161 aaccttcaaa ttcgagatgg agaaacattg cataccactt ctgtggaagt accggaagtt
     2221 gtgtcccgtt ttcagaaact ttctaccatg ctttcagccc tgcctgccag tggaatcatg
     2281 gatttcgacc tcggcatgag tgtggtcgga gtcgtccagt atgcccgcct gctacagcag
     2341 gggcacgaag acagtaccct agccaagata aatctagcta tggatatcaa gcaactttcc
     2401 gaagcaactc tcggcagcat gattcagatt gccgggaata agtttctcaa tacagaagga
     2461 atccaggggt tcagactgga aagcgccgtc gctgaaggta tgcgctcagt agcaacccgt
     2521 accggaggca caatggggaa agccctttct gccagtgccc gtgttcttga actgcctgta
     2581 ctggaaacag ttctggggac atggaacctg tacaacagcg tcattcagct ccagcaagct
     2641 acatcttatt ctgagacaat ggctgcccgg gtacagattg cgtttgattc catttctctg
     2701 ggattaactg ccgcttcggt agctttcccg ccactaatta ttgccactgg ccccattgcg
     2761 gctattggta tgggagcttc cagtattgca cgtaatgtgg cacggaaaga agaacggcat
     2821 acacaatggc tggaatataa aaaattcctg actgatggca gtaaacacat tgttgtggcc
     2881 tctccggaaa gaggtctgct ggatttctcc ggaaacaaag tttttggaaa aatggtgctg
     2941 gatctgcgtc agtctcctcc tctcttgcat ggagaaagct cttttaacgc tgaccgcaaa
     3001 atcggtcatc gtccggatct gggggactgg caaattcgtg agaaggtggg gtatgccaac
     3061 agtatcagtc cctactcttc cctggcgcac ggttacgcca acagtaaatg gccacaaaca
     3121 ataccgaaaa ttccctcggg agaatatgac accataattc tgggctacgg tcaccagtat
     3181 caggccaata cggaaataga atatctgtct aactggattg tatggcggga agccgtacca
     3241 gacagtactt cccgccacaa acgtcctcct ctggaggttc ttaatagtca gtgtactgtg
     3301 atagctggag agcgtaaaac cacagtactt cccctgagag tgctcagcga tctgacaccg
     3361 gaatgcacag aacaggctat atcgttaaaa gattataaat tcatactgag agggggaagc
     3421 ggtgggctgg ctgttcaggt cggtggcgcg ggatattatg atattgatgc aaatcctgtg
     3481 gcaaaagaaa atacgctctc ttttcgcggg ctaccggaag agtttccgct cgcctttgat
     3541 ttatcaaaac aaacacagtc ggtcatgctg aaaacaacgg acggtgaggt gccggtaatg
     3601 accatcaccc agaagggaat aaacaccctg gtcggtacaa cggccggcga aaactggcta
     3661 acgggtaacg ataaggacaa taccttccat acgagttctg gtggcggtac tgtcatctct
     3721 ggtggaggga ataaccgcta tattatcccc cgcgatttaa aaactccgct gacactgacg
     3781 ctgtctaata gctcggtctc tcacgagatc cttctgccag aaacaactct gacagaatta
     3841 aaacctgtcg cctttgagct gagtctgatt tactgggccg ggaacaatat aaaggttcag
     3901 ctggaggatg agacacaact gaaccgtttt gccggaaact tcagggggca taccagtgat
     3961 ggcattactc tggaggcggt ttcccaggaa aatggtattc aactgggggt ttcatcatgt
     4021 gatgttcaac gctggcaggc tgtttatccg gaagaaaaca acagaccaga cgccatactg
     4081 gacaggctgc atgatatggg atggagcctg gcccccgagg tcaggttccg gggaggagaa
     4141 acatctgcca gctatgaccc cctgaaccgt cagctcgttt accggcttca ggagcattac
     4201 tcggaattca ggctgaccgg cagtcgccat tacaccacgg ctgtaaccgg aacccccgga
     4261 agccggtaca ttattacggg gccggataca gcacagatat caccggcaca aatcatactg
     4321 gccggtgata atgaccatcc ggaaacgatt gatttgcttg aggccagtcc tgttctggtt
     4381 gaagggaaaa aagacaaaaa cagcgtgata ttaacgattg ctacgattca gtattccctt
     4441 caactgacaa tatccgggat cgacgaatcg ctgcccggga caacccgtgt ggcaattcag
     4501 cctcaggata cccgtttact gggtgacgta ctccggatct taccagataa tggtaactgg
     4561 gtggggattt tccggagtgg tcatacacca acggtaaacc ggctggaaaa tttgatggca
     4621 ctgaatcagg taatgacgtt cctgccccgg gtatccggaa gtgcagagca ggtattatgc
     4681 ctcgaaaacc taggtggcgt aaggaaaaaa gtggaggggg agttactgtc agggaagctg
     4741 aaaggtgcgt ggaaagccga aggtgaacct actgttccgg taaatatctc agatctaagt
     4801 atcccaccct attcacgtct gtatctgatt tttgaaggga aaaataatgt gttgctacgc
     4861 agtaaagtac atgcagctcc gttgaaaata acatccgcag gagagatgca gttatctgaa
     4921 aggcagtggc aacagcagga acatattatt gtcaagcccg acaacgaagc cccctcatta
     4981 atactcagtg aatttcgtcg tttcactatt tcatcggata aaaaattttc tttaaaactg
     5041 atgtgccatc aggggatggt ccgcatcgac cgcagatcat tatcggtcag attgttctat
     5101 ctgcgtgaac agccaggtat cggcagttta cgtctgacgt tcagagattt tttcacagaa
     5161 gtgatggata caacggacag ggaaattctg gagaaagagc tgagaccaat tctgatagga
     5221 gatacacacc gctttatcaa cgctgcatac aaaaatcatc tgaatatcca gttaggagat
     5281 ggcgttctga atctggcaga cattgttgcg gaatacgccc gtattcaaaa ggaagaaaca
     5341 tcaaaaatat tgtatcaata tcaaggtgcc atgaaaaaaa aaacagatgg accatctgtg
     5401 gtagaagatg ccattatgac cactactgtc acaacagatt caggtgaacc attccctacc
     5461 ttccacccgt ggtatacaga tgatttatca gggcgttata agagcgtacc tatggcaaga
     5521 aaagcagata ctttgtatca cctgacacca aaaggtgatc tacagataat atatcaggta
     5581 gctacaaaaa tggtgaatca ggcgatgatt gtatccctgc caaactaccg acacgagtgg
     5641 gaaaaatata atttaagcat cttatccgaa atccctcaga acaataatac tgttgtacat
     5701 tcaatcctca gggttaatgg ccccacaatg caggtgcgca caattgacta cagaggaacg
     5761 gatgaaaaca atcccatagt atctttttca gatacaacct tcatcaatgg tgaacagatg
     5821 ttgagttatg actcgcattc atcagggcga gtctattcca gagaagaata tatgatgtgg
     5881 gaattgcagc aacgggtatc agaagcttcc agtgcccgga cacaggatta ctggctgatg
     5941 gatgcagcgg taagaaacgg agaatggaag atcacaccag aattattacg tcacacaccg
     6001 ggatatatcc ggagtacggt atcgaaatgg tccagaggat ggctgaaaac cggcacaata
     6061 ctccagactc cagaagacag aaatacggat gtatacctga ctaccataca gaacaatgta
     6121 tttagtcgtc aggggggcgg ctaccaagtg tattatcgga ttgatggaat ggctggtgcg
     6181 gatatagcgg ataatgcacc aggggaaacc cgctgcaccc tcaggcccgg aacatgtttt
     6241 gaagtgacaa gtgtggatga aaggcattat gagtggaata tcatttatgt cacgctgaaa
     6301 acctgtggct ggagccgaaa tggccaaagc aaaacgccga atggtgacaa cctttttaac
     6361 taattaaaat ctctgttaaa gatgtataac ccggcatcta tgtgctcacc agcatataga
     6421 tgcaatgtga ttcccctgat ggtcgtatca gagatggtat gcgagcctgt acatagattt
     6481 gtgtaattgc ctgattttga tatgttcaat ccaacatcaa aagcaggtta atttatggac
     6541 gaaaaacagt tgcaggctct ggctaacgaa caggccaaaa atctcaaaac ccctgaagat
     6601 ctcagccagt tcgatcgcct gctgaagaaa atcagcgttg aggcagctct caacgctgaa
     6661 atgtcccacc atctgggcta cgataaaaac cagcctaaac cgggtgccaa ctcccgcaat
     6721 ggctattcca caaagaccgt tatcaccggt gatggccccc tggaactacg cactccgcgc
     6781 gatcgtgatg gctcttttga accgcaactt gtgaagaaaa accagacccg gatcaccggg
     6841 atggataacc agatcctgtc gttgtacgcc aaaggcctga caaccgtaag cgtacagcct
     6901 gaaccgtctg gtcagaatct gacgaattag agtaagctga aagattacca atact
//
LOCUS       DAZUDJ010000142         6922 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.144, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000142 DAZUDJ010000000
VERSION     DAZUDJ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6922
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.144"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            357..521
                     /locus_tag="ACHY1N_004817"
     CDS             357..521
                     /locus_tag="ACHY1N_004817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046969.1"
                     /translation="MNQLPRRALSRYGLTFQGNILSVNCQCRMLTRVRRKHSTSPVEN
                     SLITNLSFVG"
     gene            complement(525..743)
                     /gene="ydfC"
                     /locus_tag="ACHY1N_004818"
     CDS             complement(525..743)
                     /gene="ydfC"
                     /locus_tag="ACHY1N_004818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdfC"
                     /protein_id="HFS4046970.1"
                     /translation="MQKREPVIIAPDYTNDELYEWMHQKINAAQDLKWANEVRAKQAE
                     NLSSLEQDITNLEKAAALTIARMITYPR"
     gene            complement(773..901)
                     /locus_tag="ACHY1N_004819"
     CDS             complement(773..901)
                     /locus_tag="ACHY1N_004819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046971.1"
                     /translation="MDFDTIMEKAYEEYFEGLAEGEEAHSFNEFKQVLSSSAKSNG"
     gene            complement(903..1058)
                     /locus_tag="ACHY1N_004820"
     CDS             complement(903..1058)
                     /locus_tag="ACHY1N_004820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HFS4046972.1"
                     /translation="MDTIDLGNSESLVCGVFPNQYGTFTAMTYTKSKTFKTESGARRW
                     LERNSGG"
     gene            complement(1377..1853)
                     /gene="racR"
                     /locus_tag="ACHY1N_004821"
                     /gene_synonym="rarC"
     CDS             complement(1377..1853)
                     /gene="racR"
                     /locus_tag="ACHY1N_004821"
                     /gene_synonym="rarC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor RacR"
                     /protein_id="HFS4046973.1"
                     /translation="MLSGKDLGRAIEQAINKKIASGAVKSKAEIARHFKVQPPSIHDW
                     IKKGSISKDKLPELWRFFSDVVGPEHWGLNEYPIPTPSTSDTKSELLDINSLYQAASD
                     EKRAIVAFILSGNATEPSWVDHDVRAYIAAMEMKVANYLKNQESKRKSQNITKTGT"
     gene            1978..2301
                     /locus_tag="ACHY1N_004822"
     CDS             1978..2301
                     /locus_tag="ACHY1N_004822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4046974.1"
                     /translation="MKKDNYSFKRACAVVGGQSAMARLLGVSPPSVNQWIKGVRQLPA
                     ERCPAIERATKGGVLCEELRPDVDWTYLRRSSCYSQNMSMKQPNDENDHTRSIKRQMI
                     HENQT"
     gene            2285..2710
                     /locus_tag="ACHY1N_004823"
     CDS             2285..2710
                     /locus_tag="ACHY1N_004823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin YdaT family protein"
                     /protein_id="HFS4046975.1"
                     /translation="MKIKHEHIRMAMNAWAYPDGEKVPAAEIARTYFELGMTFPELYD
                     DSHPEALARNTQKIFRWLDKDTPDAVEKMQALLPAIEKAMPPLLVARMRSHSSEYYRE
                     IVERRDRLVKDVDDFVASAVVLYDQMNRGGPAGNAVVMH"
     gene            2733..3695
                     /locus_tag="ACHY1N_004824"
     CDS             2733..3695
                     /locus_tag="ACHY1N_004824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310303.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4046976.1"
                     /translation="MSSKLHGLVWEGCAFTGMILSRVAVMARLADYSNDEGVSWPAIE
                     TIRRQIGARSESTVKSAIAELAKEGWLTKEERKVGGRNVSNIYRLNVEKLEAAAAAAR
                     ESYKPKRKISPAKNDPLTVDPSNIDPSTVDPSNFDGSTVDKKLPIRGAMIDPDPSVLK
                     PDPSDKRSSCPDASQPDPQTAEQDFLTRHPDAVVFSAKKRQWGSQEDLVCAQWIWGRI
                     VSLYEQAASDDGEITRPKEPNWTAWANDVRTMRMLDGRTHRQICEMFGRLQRDSFWVK
                     NIMSPAKLREKWDELVIRLGRSPAQRCVNHISEPDTEIPPGFRG"
     gene            3702..4442
                     /locus_tag="ACHY1N_004825"
     CDS             3702..4442
                     /locus_tag="ACHY1N_004825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000788752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4046977.1"
                     /translation="MKNIAAVGVLERIRRLAPQGAVPPYRTVEEWREWQLAEGRKRSE
                     EINRLNHQVRVEKILNRAGIQPLHRKCSFGNYRVQNDGQRHALSQAKSIADELMTGCT
                     NFVFSGKPGTGKNHLAAAIGNRLMAKGRSVIIVTVSDVMSVLHDGYDNGQSGEKFLQE
                     LCGVDLLVLDEIGMQRDTRNEQVTLNQIVDRRTASMRSVGMLTNLNHAAMSTLLGDRV
                     MDRMTMNGGRWVNFNWESWRSNVGRQGM"
     gene            4468..5238
                     /locus_tag="ACHY1N_004826"
     CDS             4468..5238
                     /locus_tag="ACHY1N_004826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
                     /protein_id="HFS4046978.1"
                     /translation="METVLHALKAMGKANSVELAARLDISREEVLNELWELKKNGVVD
                     KTGHTWFLAVEGEAGVTEGQALQPEAPDVVTEEVAPKVTADMMVEFIGQDGAKTCEEL
                     AGKFGVSTRKVASTLAVVTATGRLARVNQNGKFRYCMSGGNLPADPKAAPVTKNDGKA
                     FPQPAGAALPVREAATQEEIKTETVADIVQPLLSFTETQADELIFPSLRRANLALRRA
                     KSDVQKWERVCAALRELNKHRDIVRQITDSSRRVVSEK"
     gene            5254..5649
                     /locus_tag="ACHY1N_004827"
     CDS             5254..5649
                     /locus_tag="ACHY1N_004827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HFS4046979.1"
                     /translation="MAKPFTHEQREELKARIIGLVRKNERMTISQLERATGAGWHSVR
                     RCLVDVLACGDLYMPGKYGVFTSEQVYRVWRKAAEKATDQTLIRKLPDGEIRRYDRQQ
                     NIICGECRKSEVMLRVLAFYQGNFQEAVL"
     gene            5706..6290
                     /locus_tag="ACHY1N_004828"
     CDS             5706..6290
                     /locus_tag="ACHY1N_004828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF551 domain-containing protein"
                     /protein_id="HFS4046980.1"
                     /translation="MITFTKEQLISHVSENVKAMKFAVKQTVFKNSLEAIELDLALAL
                     VAQASLEAEPVLYMNRFTGKTFSLEEQPGADKEPEIYVPLYAAPPDSAAMLQAGNFRE
                     NKGSSTNNFREISETSTNYPVTPDGWISCSERMPDDGQHVIILCDGAFVLYAQYRDGE
                     FFDVVRNGDEFFETQSRNVTDWMPLPEPPQEVRQ"
     gene            6406..6510
                     /locus_tag="ACHY1N_004829"
     CDS             6406..6510
                     /locus_tag="ACHY1N_004829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046981.1"
                     /translation="MSDDISLAMEGALAVIAVVGVYCLVVFLMDRLGN"
     gene            6756..6911
                     /gene="hokD"
                     /locus_tag="ACHY1N_004830"
     CDS             6756..6911
                     /gene="hokD"
                     /locus_tag="ACHY1N_004830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HFS4046982.1"
                     /translation="MKQQKAMLIALIVICITVIVTALVTRKDLCEVRIRTGQTEVAVF
                     TAYEPEE"
BASE COUNT         1787 a         1535 c         1887 g         1713 t
ORIGIN      
        1 ctccaggtga cgttaaccag ttaacaatta acgccggata cagagaatcc aaccataaca
       61 ctgtttttgg ttttaactgt tccgcgtgcg cttagccgca ttcaccgcat cacaaaattc
      121 actttaaaaa gggcggcaga gcagtcacgg agtaaaactg ataccgccaa acgtcaccag
      181 aaaattgata acagagggcg ttgcagcggg gttgtcactt aagcgtatgg tcaacctgac
      241 aacccggtgt cctcaacggg ggaaggaata accccgccat acttaccgcc gcgccatttc
      301 gcggattgcc acaaccggaa gcgcacggtc gacgaaaatt taacgacagg ctatctatga
      361 accagctacc tcgccgtgcg ctttcgcgtt atggtctgac ttttcaggga aatatccttt
      421 cagtaaactg tcagtgccgg atgctcaccc gtgtccggcg caagcactcc acctcacccg
      481 tggagaactc cttaattacc aaccttagct tcgttggtta gctattaacg cgggtatgta
      541 atcattctgg caatggttaa tgccgctgct ttttccagat tggtgatatc ctgctccaga
      601 gaggacagat tttcagcctg cttagccctg acttcattag cccatttcag atcctgcgct
      661 gcattaattt tctggtgcat ccactcataa agttcatcat tggtatagtc tggcgcgatg
      721 atgacgggtt ctcgtttctg catactgatt cctcgcggtg ctgtttcgct tatcagccat
      781 tagattttgc cgaactggaa agcacctgtt taaattcgtt gaagctgtga gcttcttcgc
      841 cttcggcaag gccttcgaag tattcttcgt aagccttttc catgattgtg tcgaaatcca
      901 tatcacccac ctgaatttct ttccagccag cgacgcgctc cagattcggt tttaaacgtt
      961 ttgcttttgg tatacgtcat tgcggtgaac gtaccgtact ggttggggaa cacgccacat
     1021 accagagatt cgctgttgcc aagatcgata gtatccatgc tgacctcatt tccccttaac
     1081 gccggggtag cggaacaaaa acctgctgca tagttattaa agttgaaccc tgccgtcatg
     1141 ttcttacgcc tcgggctggc tacttaaccc gtgaccactg cctggtaact cgaggtattg
     1201 ccctgtattg tgtgggacgg gatgggttgg tatgggaaaa ctataggaaa tgcctaatta
     1261 cttgtcaata ggctatgcct aataatttgg gcgcaaccta ataggtgatg gtttgtggaa
     1321 gaggtagtag gagttaacta acgggaacta ggaatttccc gtcggaccat ataagtttaa
     1381 gttcctgtct tggtgatgtt ctggcttttc cgttttgatt cttgattttt cagatagtta
     1441 gctaccttca tttccattgc ggcaatgtag gcgcgaacgt catgatcaac ccaactaggc
     1501 tccgtagcat ttccagataa gatgaaagcc acaattgctc ttttttcatc agaggcggct
     1561 tgataaaggc tgtttatgtc taaaagttca ctttttgtat ctgaagtgga tggggttggt
     1621 atggggtatt cgttaagccc ccaatgctct ggaccaacca catcagaaaa gaaacgccat
     1681 agttctggaa gtttgtcttt acttatcgaa cctttcttaa tccagtcatg gattgatggt
     1741 ggttggactt tgaaatgacg tgcgatttcc gcctttgatt tgacggctcc tgatgcaatt
     1801 tttttgttaa tggcctgctc tatcgctcgg cctaagtctt taccactaag cattgcttaa
     1861 tagtctccta tgcgcatcgc gttaggcaat ccctactctc gatgtattag gcatagccta
     1921 ttgacaattt cattaggcta agcctaatat tgttgcgtgt tttttggagt tcattcgatg
     1981 aaaaaagata actattcatt caaacgagct tgtgctgttg tcggtgggca atcagcaatg
     2041 gctaggcttt taggtgtatc tcctccaagc gtaaatcaat ggatcaaagg tgtacgtcag
     2101 ttacctgctg agagatgtcc tgcgattgaa cgagcaacaa aaggtggtgt tctgtgtgaa
     2161 gaacttcgtc ctgatgttga ttggacatac ttacgacgct cgtcatgtta ttcgcagaat
     2221 atgtcgatga agcaaccaaa tgacgaaaac gatcataccc gaagcatcaa gaggcaaatg
     2281 attcatgaaa atcaaacatg agcacatccg catggcgatg aatgcctggg cataccctga
     2341 tggtgagaaa gttcctgcag ctgaaatagc ccggacttat ttcgaactgg ggatgacgtt
     2401 ccctgaactg tacgacgaca gccatccgga agccctggcc cgtaataccc agaaaatttt
     2461 ccgttggctg gataaagaca cccctgatgc tgttgaaaaa atgcaggctc tgttaccggc
     2521 gatcgaaaag gcgatgccgc ctttgctggt ggcccgtatg cgcagccaca gttctgaata
     2581 ttaccgtgag atcgtcgaac ggagggatcg gctggtgaag gatgtcgatg attttgttgc
     2641 gtcagcggtt gttttgtatg accagatgaa tcgcggcggc ccggcaggga atgctgtggt
     2701 gatgcactaa aagcacggtg ttcgggggtt ttatgagcag caagcttcat ggtcttgtct
     2761 gggaagggtg cgccttcacc ggcatgatct tatccagggt ggcggttatg gcccgtcttg
     2821 cagactacag caatgacgag ggcgtgtcat ggcctgccat tgaaactatc cggcgtcaga
     2881 tcggtgcaag aagtgaatcc acagtgaaat cggctattgc agaactggcg aaagagggct
     2941 ggctgacgaa ggaagagcgt aaggtcggtg ggcgtaatgt aagcaatatc tatcggctta
     3001 atgtggaaaa actcgaagca gctgcggcgg cggcgcgtga gtcatataaa ccgaaaagaa
     3061 aaattagccc ggcaaaaaat gacccgttaa cagttgaccc gtcaaatatt gacccctcaa
     3121 cggttgaccc gtcaaatttt gatggatcaa ctgttgataa aaaactgccg attagggggg
     3181 cgatgattga ccccgatccg tcagtattaa aacctgatcc gtcagataaa agatcttctt
     3241 gtccggacgc ttcgcaaccg gacccgcaga cggctgaaca ggatttttta acccgacacc
     3301 ctgacgcggt tgtgttcagt gcgaaaaaac gccagtgggg aagtcaggaa gatttggtgt
     3361 gcgcacagtg gatctgggga cgaatcgtga gtctttacga gcaggcggcc agcgatgatg
     3421 gcgagatcac tagaccgaaa gaacccaact ggacagcatg ggccaatgac gttcgcacaa
     3481 tgcggatgct ggatggcaga actcacagac aaatttgtga aatgtttggg cgtctccagc
     3541 gggattcgtt ctgggtaaaa aacatcatga gtccggcaaa actccgggaa aaatgggatg
     3601 aactggttat ccgcctgggg cgttcgcctg cgcagcgttg cgtgaatcac atttctgaac
     3661 cggacactga aataccgccg ggattcaggg ggtgacgtgt catgaaaaac attgcggcag
     3721 ttggggttct tgaacgtatt cgcagacttg caccacaggg ggcggttcca ccgtaccgga
     3781 cggtggagga gtggcgggaa tggcaacttg ctgaaggacg aaaacgcagc gaggagatta
     3841 accgcctgaa tcatcaggtg cgggttgaaa aaatcctgaa ccgtgcgggc atccagccgc
     3901 ttcacaggaa gtgctcattc gggaactacc gggtgcagaa cgacggtcag cgccatgctc
     3961 tgagccaggc gaaatccatt gccgatgaat tgatgaccgg atgtacaaac ttcgtgttca
     4021 gcggtaaacc tggtaccggt aaaaatcacc tggcagcagc gattggcaat cggctgatgg
     4081 cgaaggggag aagcgtgatt atcgtcaccg tgtccgatgt catgagcgtg ttgcatgacg
     4141 gctacgacaa cggccagtcc ggggaaaaat ttttacagga gctttgtgga gttgaccttc
     4201 tggtccttga tgaaattggc atgcagcggg atacgcgcaa cgagcaggtc acgctgaacc
     4261 agatagtcga ccgcagaacg gcttcgatgc gtagtgtcgg aatgctgacg aacctgaatc
     4321 acgcagcgat gagcacactc ctcggagatc gggtgatgga ccgtatgacc atgaatggtg
     4381 gtcgttgggt gaattttaac tgggagagct ggcggtcaaa cgttggacgt cagggtatgt
     4441 gagaattttt gacgaggtaa attttcgatg gaaactgtat tgcatgcact gaaagcgatg
     4501 ggaaaagcca attctgttga actggcggcg cggcttgata tcagccgtga agaagttctt
     4561 aacgaactgt gggaactcaa aaaaaatggc gttgttgata aaacgggtca cacctggttt
     4621 ctggctgtcg aaggtgaagc cggggtaacc gaagggcagg cactacaacc tgaagcgccg
     4681 gatgtggtaa ccgaagaggt cgctccaaaa gttaccgcag acatgatggt tgagtttatc
     4741 ggtcaggatg gtgctaaaac gtgtgaggaa ctggcgggta agttcggcgt cagtactcgc
     4801 aaggttgctt ccacgctggc ggtggtaacc gcaacggggc ggctggcacg cgttaatcag
     4861 aacggtaaat ttcgttactg catgtcgggg ggtaatttac cagcagatcc gaaagccgcg
     4921 ccggtaacga aaaatgatgg taaggccttt cctcagccag caggtgctgc gttaccagtc
     4981 cgggaagccg caacacagga agaaattaaa acagaaactg tggcggacat tgtgcagccg
     5041 ttgctatcgt ttaccgaaac gcaagcagat gagctgattt ttccgtccct gcgcagggca
     5101 aacctggcgc tgcgcagggc gaaaagtgat gttcagaagt gggagcgagt ctgcgccgcg
     5161 ctgcgggagc tgaacaagca ccgggatatt gttcgacaga ttactgattc ttcccgccgt
     5221 gttgtatcgg aaaagtgata gccggaggcg cttatggcga aaccttttac acacgaacag
     5281 cgtgaagaac tgaaggcccg aattatcggg ctggtacgca aaaatgaacg catgacgata
     5341 tcacaactgg agagagcgac gggagcaggc tggcattcag tcagacgttg ccttgtggat
     5401 gtactggctt gtggcgattt atacatgccc ggtaaatacg gtgtttttac atcagaacag
     5461 gtgtatcgcg tatggcgtaa ggcagcggag aaagcaaccg accagacatt gattcgaaag
     5521 ttaccagacg gagaaatacg ccgctacgac agacaacaga acataatctg tggcgagtgc
     5581 cggaagagtg aagttatgct gcgtgtactg gcgttctatc agggcaattt tcaggaggcg
     5641 gtactgtgag tgaattagct atcaggcttc aattgtcgct ggcattcgca tcaaaggaga
     5701 atgagatgat cacttttaca aaagagcagt taatcagtca tgttagtgaa aatgtaaagg
     5761 cgatgaaatt tgcagtaaaa cagacagtat tcaaaaattc tctcgaggca attgagttgg
     5821 atttagcact ggcccttgtt gctcaggctt cgctggaagc agagcccgtg ctttatatga
     5881 atcgatttac cggaaagaca ttctcactgg aagagcaacc cggtgctgat aaggaaccgg
     5941 aaatatacgt gccgctatat gctgccccgc cagacagcgc cgccatgctt caggctggaa
     6001 actttcggga aaataagggt tcgtcaacca ataattttcg ggaaatctcg gaaacgtcaa
     6061 ccaactatcc ggtaactccg gatggttgga taagctgtag tgagcgaatg ccggatgatg
     6121 gtcagcacgt aattatttta tgtgatggcg cattcgttct ttatgcgcaa tatcgagacg
     6181 gtgagttttt tgatgtagtc cgtaatggtg atgaattttt cgaaacacag agccgcaatg
     6241 taaccgactg gatgccgcta ccagaaccgc cgcaggaggt gcgccaatga tctggcctga
     6301 agcctttgca attacaggcg ttgctatagc tattgatttt ttagtatatg ttatttgtcg
     6361 gtgggggtaa aaacgttcgc cgggattcac accaaaggag ggaatatgtc ggatgatatt
     6421 tcactggcaa tggaaggtgc tctggctgtt attgctgttg tgggcgttta ctgcctggtt
     6481 gtgtttttga tggatcgact agggaactga attcattacg atatgggaat tcccatatcg
     6541 ggtaaaaacg gtttgcggta aagcgagagt taagtagaat tgctgcgggt gcttgaggct
     6601 gtctgcctcg ggcatgccac cgtaaggcag acagagaaaa gccccagtta acattacgcg
     6661 tcctgcaaga cgcctaacat taatctgagg ccaatttcat gctagacata tgtaggttag
     6721 cctcttacgc gccgaaaggc aaggagaagc aggctatgaa gcagcaaaag gcgatgttaa
     6781 tcgccctgat cgtcatctgt atcaccgtca tagtgacggc actggtaacg aggaaagacc
     6841 tctgcgaggt acgaatccga accggccaga cggaggtcgc tgtcttcaca gcttacgaac
     6901 ctgaggagta agagacccgg cg
//
LOCUS       DAZUDJ010000143         6741 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.145, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000143 DAZUDJ010000000
VERSION     DAZUDJ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6741
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.145"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(193..1122)
                     /gene="fdhE"
                     /locus_tag="ACHY1N_004831"
     CDS             complement(193..1122)
                     /gene="fdhE"
                     /locus_tag="ACHY1N_004831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HFS4046983.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLREL
                     AENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKH
                     WQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFI
                     WAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAV
                     ADDLASLVLDARMEQEGYARSSINPFLFPGEGE"
     gene            complement(1119..1754)
                     /gene="fdoI"
                     /locus_tag="ACHY1N_004832"
     CDS             complement(1119..1754)
                     /gene="fdoI"
                     /locus_tag="ACHY1N_004832"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HFS4046984.1"
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLM
                     QIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     gene            complement(1751..2653)
                     /gene="fdoH"
                     /locus_tag="ACHY1N_004833"
     CDS             complement(1751..2653)
                     /gene="fdoH"
                     /locus_tag="ACHY1N_004833"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase O subunit beta"
                     /protein_id="HFS4046985.1"
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKC
                     TLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHY
                     VGVGPNRADEEENNLHEEKDEERK"
     gene            complement(2666..5716)
                     /gene="fdnG"
                     /locus_tag="ACHY1N_004834"
     CDS             complement(2666..5716)
                     /gene="fdnG"
                     /locus_tag="ACHY1N_004834"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA];
                     GO_function: GO:0047111 - formate dehydrogenase
                     (cytochrome-c-553) activity [Evidence IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_except=(pos:complement(5129..5131),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HFS4046986.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFI
                     HSESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLS
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTAAVADYYAPIR
                     SGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDYGFEDGLFTGYDAEKRKYD
                     KSSWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKDAFLKVCE
                     YIAETSAHDKTASFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEGQVNYWGNYPKFFVSM
                     MKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGYICQGFNPVASFPNK
                     NKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAEQGGANPDQVLNMTWNY
                     AIPHEPKSEEVAMESNGKALADITDPATGAVIIKKGQQLSSFAQLRDDGTTSCGCWIF
                     AGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     LQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            5910..>6741
                     /gene="fdhD"
                     /locus_tag="ACHY1N_004835"
     CDS             5910..>6741
                     /gene="fdhD"
                     /locus_tag="ACHY1N_004835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HFS4046987.1"
                     /translation="MKKTQQKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVA
                     LVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSS
                     RRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDF
                     QPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLS
                     N"
BASE COUNT         1462 a         1836 c         1837 g         1606 t
ORIGIN      
        1 agcgcatcag gcaatcttac gcttgtcatc agtgacatac caataacctt atcgatgtgt
       61 tggagggaag aacgaggcaa acaggcactg gcggcatagc ttgaggtggt aacgcggaat
      121 acgggagatg gtgtcgtcac accctatggg ctgtaatccg ggcgacctgc gccacccgga
      181 aaacgtcaga gattactccc cttcacccgg gaacaggaac gggttgatgg aactgcgggc
      241 gtagccttct tgctccattc gcgcgtccag taccagagag gcgaggtcat ctgccacggc
      301 ttcaactttc ggttcttttt cctgataaag aatcttcagg taagtgccgc agtcatcgca
      361 gctttcggct ttaatcgcgg cctgttcgtc atccagcgac cagtaatgca gtttgccgct
      421 ctgttcacag ttgctgcatt ttacgcgcac tacgtgccat tcggtttcac acaggttgca
      481 gtgcaggtaa cgcagaccct gagtggtgcc aatttgcacc atgctggaca ccggcataga
      541 accacaaacc gggcaatatt gacgttgctc gccgtattca gcgcgggctt tgccggggat
      601 cagattggcc atctgcgccc agtagagcga cagtgcagcc cagataaacg gcgctttatc
      661 gctgctgacg gatgagaaat cagaggcaaa cagtgcgctg gccatatctt ccagctcctg
      721 agtcgatgcc ttctccagat tctcaatcac tgccagcgcc gggccgctca tttcaggttt
      781 cagctcagca atcagcgcca tcagcagctt ttgccagtgc ttatcacgcg gcagaacgtg
      841 aatatccagc gggggcttgc cctgtgcgct ggcttcttta atgcgcgcgg tcagatccat
      901 ctccagcgga tggtcgtaca gcaccacttc ctgggcgtgg gcgataagcg cagcaaagcg
      961 caggtaatca cccagcggat tattttctgc cagctcgcgc agacgctcgg cgcggcggtt
     1021 gtataaattc ttgagccgag ggaacaataa cggcggaatc atatccgccg tacgtttctc
     1081 gctcgaaccc agctcatctt gcgggattat gcgaatactc attcagcttt cttttccgtt
     1141 gtcttgcgga cctcacggta ccagcgcggg tgatgtttct tcgcccaggc gctggtaacc
     1201 catccttcca ccatggcggt aatcgtgcct ttcacccaaa gggcggcgta gatatgcacc
     1261 atgataacca caattaacgc cactgcggca aatgaatgca gcattaacgc gaatcggatc
     1321 accgggattg agaaagcagg cgcaaaataa ggacgccaga taatcacgcc gctcaccagc
     1381 agcagaacca ggaaaataat cgccgcccag aaaacgcatt tctgaccgaa gttataacgc
     1441 ccggtgtcac ctacttcctc gttgacgacg atcttacgaa tattcttcgc ccaaaagata
     1501 tcatcccgat tgattaggtt gtgatgccag taacggaaaa acatgatgat gaacgaggca
     1561 aacataacca cgccgacaaa cgggtgcaga attcgcgcca gctgcggtgt gcccatgatt
     1621 tgcatcaacc agttgaagga cgggaacaaa aagcccagcc cgctcaccgc cgccaggatg
     1681 aagcagaagg cggtgatcca gtggttgata cgttccggcg cggtgtagcg cacgatggtg
     1741 tcacgtcgtt tcatttgcgc tcctcgtctt tctcttcgtg cagattattc tcttcctcat
     1801 ccgcacggtt cggaccgaca cccacgtagt ggaagatact ggccgcaaag gtagccgcaa
     1861 agccaacagc cgcgagcggt ttccagatgc ctttccagaa tttcacggtt tcgctgattt
     1921 ccgggttctc cggcaagcca tgatacagat ttggcttgtc agcatggtgc agcacgtaca
     1981 tgacgtgtgt accaccgacg cctgccggat cgtacagacc cgcattgtcg taaccgcggg
     2041 ttttcagctc agcaacgcgc tcgctcgcca gcgttttcat cgactctttc gtaccgaagt
     2101 gaatcgcgcc cgttgggcag gtcttcacgc aggctggttc ttgcccaacc accacgcggt
     2161 caacgcacag cgtacatttg tagacgcggt tgtcttccgg gttgaggcgc ggaatgtcga
     2221 acggacagcc cgcaatgcaa taaccgcagc caatgcactg ctcggactgg aagtcgacga
     2281 taccgttggc atactgaata attgcacctt ccgccgggca cgctttcagg cagcctggat
     2341 cggaacagtg catacagccg tctttgcgga tcagccattc cagtttgtcg ttctgctcca
     2401 cttccgagaa gcgcattacc gtccacgatt tggcgcttaa atcattgggg ttgtcgtaca
     2461 ccccaatgtt attgccgacg gtatcgcgaa tgtcgttcca ctctgaacac gccacctgac
     2521 aggctttaca gccgatacag gtggtgacgt cgatgagttt cgccacttct tcctggaagt
     2581 cccgcgcctg aggcgcgggg gtcagaccgt tagtcgcgga acgacgaatg atatcttgag
     2641 attgataagc catatgtcgt ctccgttaca ccttttccac attcacaagg aaggacttaa
     2701 actccggcgt ctgcgtgttc gcatcaccaa cgaatggcgt taacgtattg gcaataaagc
     2761 cttttttagc tacgccttca taaccccagt gaatcggaat accgatggta tcgatatctt
     2821 tgccgttcgc tttcagcgta cgaatacgtt tggtcaccac cgctttggct ttgatatagc
     2881 cacggttgga ggagactttc acggtatcgc cctgggcaat gccaagttta ttcgccagcg
     2941 actccccgat ttccacaaac tgctctggtt gcaaaatcgc gttcaacagc gcgtgtttgg
     3001 tccagtagtg gaagtgctcg gtcagacgat aggtggttcc gacatacggg aacttatcgg
     3061 ctttacccaa tgcttcggcg tcgtctttaa agatacgtgc agccgggttc gagataacgt
     3121 ttggatgcag cgggttagtt cccagcggcg tttcaaacgg ctcgtagtgt tccgggaacg
     3181 gaccttccgc catcttatcg agggcaaaca gacgccccat gccttcctgc tgcatgataa
     3241 acggcccgac gccgctaccc ggaggcgctg cgctgtagtc cggaatatcc cagccggtcc
     3301 acttagtgcc gtcccatttc agcaactgac gcttcggatc ccacgggtta ccctgcggat
     3361 ctgcggaggc gcggttatac agaatgcggc ggttaagcgg ccatgcccat gcccagccca
     3421 gcgtgttacc gaggccagac ggatcggcgt tatcacgacg cgccatctgg ttgccttccg
     3481 gcgtccagct accggcgaaa atccagcagc cacaggaggt tgtaccgtca tcgcgcaatt
     3541 gggcgaacga gctaagttgt tggcctttct tgatgataac cgcaccggtt gccggatcgg
     3601 taatatcggc cagcgcctta ccgttgctct ccatcgctac ttcttccgac ttcggctcat
     3661 gcggaatggc gtagttccag gtcatgttca gcacctggtc cgggttcgcg ccaccctgtt
     3721 cggcatacat cttgcgcaag cgcaggaaga taccggagag gatctcgcca tcagtcagcg
     3781 caatccccgg ggcgtccgca cctttccagt gccactgcaa ccagcgacct gagttaacga
     3841 ttgaaccgtt ctcttctgcg aagcaggtcg atggcagacg gaacacttcg gtctggatct
     3901 tcgacgagtc aacttcgttc agctcaccgt ggttctgcca gaagttagag gtttcagtgt
     3961 tcagtgggtc gatggtgacg aggaacttca gtttcgacag acaaccgatc actttgtttt
     4021 tgttcgggaa tgaggcaaca gggttaaagc cctggcagat atagccattg accttgccct
     4081 ctttcatcat ctcgaagtat tgcaggacgt cgtagccttt atcccacttc ggcaaccagt
     4141 caaagcccca gctattttcc gccgtcgctt tatcaccaaa gaaggccttc atcatagaga
     4201 cgaagaattt cgggtagttg ccccagtagt ttacctggcc ttccagcagc ggttttggcg
     4261 tgttggcggt aaggtaggtt tgcagatcgg tctgcttctc gcttggcagc gtcatgtaac
     4321 ctggcaggct ctgcgacagc agccccaggt ccgtcagccc ctgaatattg gagtgaccgc
     4381 gcagggcgtt aacgccgccg ccggccatcc ccatattgcc gagcagcagc tggatcatcg
     4441 ccatcgtacg aatgttttgc gcaccaacgg agtgttgcgt ccagccgagg gcatacagga
     4501 acgaggcagt tttatcgtga gcactggttt ctgcgatgta ttcgcagact ttcaggaacg
     4561 cgtcttttgg cgtaccacag atgttttcaa ccacatctgg cgtgtagcgg gaaacgtgct
     4621 gtttcagcaa gttccacacg cagcgcggat gttgcagcgt ggtatcgcgt ttggcgaagc
     4681 cgttttcgtc cagttcataa gtccaggagg atttatcgta cttgcgtttt tccgcgtcgt
     4741 agccggtgaa caggccatct tcaaagccgt aatcctcacg cactatcagg ctggcgttgg
     4801 tataggcttc ggtgtattcg cggttgaatt tttcattgtt cagcaggtac agcaatacgc
     4861 ctgacaggaa agcaatgtca gtaccggaac gaataggggc atagtagtca gctaccgccg
     4921 ccgtacgcgt aaagcgagga tcgatcacaa tcagcttcgc gccgttgtga attttggctt
     4981 ccatcgccca gcggaacccg accgggtgag cttcagcggc gttaccgccc atcaccacga
     5041 cgaggttggc gttcttgatg tcgacccagt ggttggtcat cgcaccgcga ccaaatgttg
     5101 gagcaagact tgctaccgtt ggtccgtgtc agacacgcgc ctggttgtcg accgcgagca
     5161 tacccagcgc gcgggagaat ttttgcgtta aatagccggt ttcgttactc gacgcggaag
     5221 cacacagcat cccggtggag agccagcggt taacagtcac gccttcggcg ttttgcgcaa
     5281 tgtagttagc atcgcggtct tctttcatca gtttggcgat gcgatcaaac gcctcttccc
     5341 aactgatttg ctgccattta tcagaacctg gcgcacggta ttccggaaac ttcagacggc
     5401 tttcggagtg gatgaaatcc accaggccag cgcctttcgg acaaagtgca ccgcggttga
     5461 ccgggtgatc cggatcgcct tcgatatgga agatagatgc tttggcgttt tttgctccgt
     5521 caccgaggct gtacatcaac agcccacagc ctacggaaca ataggtgcag gtattacggg
     5581 tttcgcgggt gcgcagcagt ttatactgcc gggtttccgc gagcgctacg ctgggtgcaa
     5641 aacccagtgc cgctgccgtg gtgcctgcca taccgccagc gcagatctta aagaactgcc
     5701 ttctgctgac ctgcatggat tgctccttgt ttcgacattg tcacgtccca tttacattcg
     5761 cttgctgcgt gtgcagggag tgggagttat ttttctttgc ggaaggggcc gcaaaggtcc
     5821 agaattggct caatttccct ccatccagga agggtttgta acagaatacc ataatgttgg
     5881 tgtgtgtgtt cttatctggt taagagaaag tgaaaaaaac acagcaaaaa gaaatcgaaa
     5941 atgtgacaaa tatcacaggt gttcgtcaaa ttgagttatg gcggcgtgat gatttacaac
     6001 acccacggtt agatgaggtc gcggaagaag ttcccgttgc gctggtctac aacggcattt
     6061 cgcatgtggt gatgatggcg tcgcccaaag accttgagta ctttgcgctc ggtttttcgc
     6121 tttccgaggg gataatagaa agtccgcgcg atatcttcgg catggatgtc gttccttcct
     6181 gtaatggcct tgaagtacaa attgagcttt ccagccgccg ctttatgggg ttgaaggagc
     6241 gccgccgggc gctggcggga cgtacgggct gtggcgtatg cggcgtggag caacttaatg
     6301 acatcggaaa accggtgcag ccgctaccgt tcacccagac gtttgatctc aacaaactgg
     6361 atgatgcatt acgtcatctc aacgattttc agccagtggg gcaactgact ggttgtactc
     6421 acgccgctgc ctggatgttg ccatctggcg aactggtcgg cgggcatgaa gacgtgggtc
     6481 gccatgtggc gctggacaaa ctgttaggcc gccggtcaca agaaggggaa agctggcagc
     6541 aaggtgcggt actggtttcc agtcgtgcca gttatgaaat ggtgcaaaag tcggcgatgt
     6601 gcggcgtaga gattttgttt gcggtgtctg ccgcgaccac gcttgctgta gaagtggctg
     6661 agcgctgtaa tctgacactg gtaggttttt gtaaaccggg tcgggcaacg gtttataccc
     6721 atccgcagcg tttgagcaat t
//
LOCUS       DAZUDJ010000144         6736 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.146, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000144 DAZUDJ010000000
VERSION     DAZUDJ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6736
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.146"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..201
                     /locus_tag="ACHY1N_004836"
     CDS             <1..201
                     /locus_tag="ACHY1N_004836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HFS4046988.1"
                     /translation="GRKNFLFFGSDHGGERGALLYSLIGTCKLNDVDPESYLRHVPGV
                     IADWPVNRVSELLPWRIALPAE"
     gene            complement(264..452)
                     /locus_tag="ACHY1N_004837"
                     /pseudo
     CDS             complement(264..452)
                     /locus_tag="ACHY1N_004837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767718.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(505..1503)
                     /gene="lpxM"
                     /locus_tag="ACHY1N_004838"
                     /gene_synonym="msbB"
     CDS             complement(505..1503)
                     /gene="lpxM"
                     /locus_tag="ACHY1N_004838"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052689.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009276 - Gram-negative-bacterium-type
                     cell wall [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HFS4046989.1"
                     /translation="MVPPSAVLCYHNEISRQIPVNMKNIRTEFIPRFNLTLCFPRYWM
                     TWTGIGIICVFAMVPPALRDPLLGKLGMLVGRLGKSARQRALINLSLCFPEYSDKEKE
                     NIVDAMFATASMAVVLMAELALSGPDKISHRIRWNGLEIVEKMAQNNEKVIFLVPHAW
                     GVDIPAMLIAASGRKMAAMFHNQRNPVVDYVWNSVRRRFGGKLHARNDGIASFVRSVR
                     QGYWGYYLPDQDHGPEFSEFADFFATYKATLPVIGRLSRISGARIIPLFPVYDGKTHH
                     LTIHVSPPLAIRQKSDAHIARQINEVVENFVRPHPEQYTWILKLLKTRKEGEEDPY"
     gene            complement(1577..3298)
                     /gene="cptA"
                     /locus_tag="ACHY1N_004839"
     CDS             complement(1577..3298)
                     /gene="cptA"
                     /locus_tag="ACHY1N_004839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HFS4046990.1"
                     /translation="MHLNTGQNRPTFSWSALGWAIFYFGFFSTLLQVIIFSSGYSGTN
                     GIRDSLLFSCLWLIPVFLYPDRIKIIAAVVGFILWGTSLAALCYYFLYGHEFSQSVLF
                     VMFETNAREAGEYFSQYFSLKLLLISLVYTAVSVFLWTRLRPVYIPLPWRRIVSFLLL
                     YALLLHPVVLKSLIRQEPLNDTLGKLASRMEPAAPWQFVSSYYQYHQQLNALTTFLNE
                     NSALPPLGNLRDESGERPRTLVLVIGESTQRERMSLYGYLRETTPELDALRKTDPGLT
                     VFNNVVASRPYTIEALQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTIT
                     ARNTMLTVFSRQTDRQYYMNQQRTQSAREYDTNVLKPFREVLNDPAPKKLIIVHLLGT
                     HIKYKYRYPEGQGRFDGITGHIPTGLNAKELEVYNDYDNANLFNDHVVASLIKDFRAT
                     APDGFLLYFSDHGEEVYDTPPYKTQGRNEDNPTRPMYTVPFLLWTSEKWHAAHPRDFS
                     QYVDRKYSLAELIHTWSDLAGLTYDGYDPTRSLVNPQFRETTRWIGNPYKKNGLTDFD
                     TLPYGEP"
     gene            complement(3392..4498)
                     /locus_tag="ACHY1N_004840"
     CDS             complement(3392..4498)
                     /locus_tag="ACHY1N_004840"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFS4046991.1"
                     /translation="MMKILFTESSSDIGGQELQALAQMTALQKQGHSVLLACREKSKI
                     APEARKRGHDVTFIPFRNSLHLPSILRLRRIIGEFKPDLVICHSGHDSNIAGLSRLIC
                     CHRFSIVRQKTYITRKTRTFSLNYLCDFIVVPSSAMMAHLMAEGVRTPVTVIPPGFDW
                     PALHNEAMRPLPLHIHAWAASADNVPLIVQVGMLRPEKGHEFMLRVLYQLKMEGKSFR
                     WLVVGAGREEYEARLRQQTEHLGMSGDVLMAGALFPALPVYRIASVVVMPSENEAFGM
                     VLAEASVSGVPVIASETGGIPDVIQKNVTGTLLPVGDVSAWTGALRDFLSRPERFRMM
                     AASAREDIEYRFDINRTAQIIVSLASQAKGKCNR"
     gene            complement(4498..5319)
                     /locus_tag="ACHY1N_004841"
     CDS             complement(4498..5319)
                     /locus_tag="ACHY1N_004841"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001302199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFS4046992.1"
                     /translation="MLNARHLPVLMYHHVSRCPGLVTLSPETFCEQMKWLADNNWRTV
                     TSAELEYFYQGGTLPRKSVMLTFDDGYLDNWLRAWPVLKEYNLHAHIFLITGLIGKGN
                     VRSRQEQEYSHRDCERLIADNRSDEVMLRWSEVREMRDSGLVEFHVHTHSHKRWDRLS
                     VSRAEQCRLMKEDILVGKQCLTEKLGFCSSHLCWPEGYYNRDYINLAGKLGFSYLYTT
                     ERRMNCPENGSLRIGRISTKEREHSGWLKRRLFYYTTPLFSSVLALHKGPRLPDN"
     gene            complement(5920..6054)
                     /locus_tag="ACHY1N_004842"
     CDS             complement(5920..6054)
                     /locus_tag="ACHY1N_004842"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4046993.1"
                     /translation="MPHPERNHCLLLMGYLHGVQASELLGIKLSDIDLQAGNLNIRRL
                     "
BASE COUNT         1863 a         1661 c         1459 g         1753 t
ORIGIN      
        1 ggtcgtaaaa acttcctgtt cttcggctct gaccatggtg gtgagcgggg agcgctactg
       61 tacagcctga tcgggacgtg caaactgaat gacgtggatc cagaaagcta ccttcgccat
      121 gtgcctggcg tcatagcaga ctggccggtc aaccgggtca gcgaactgct tccgtggcgc
      181 atagcactgc cagctgaata acacatcccc gtcaatacgg ccctcgctgt acgcttacga
      241 ccgctcagta aatatcaata cagttctgac gagccgctta caagctgtga ttcatacaga
      301 ctgagcacac gggctgcgac agcaacaccg atgcgttcag caagcttcag ggcttcactg
      361 cgaaattcag gcgaatgcta tttacggggt tttttactgg ttggtactgt ttttttgtca
      421 tatgagccac ctctgactga gagtttactc acttagcgtg tgtccactat tgctgggtaa
      481 gctcattatc ctgaaaaacc tgcctcagta aggatcctct tccccttctt tacgcgtttt
      541 cagcaacttg aggatccacg tatactgctc aggatgtgga cgaacgaaat tttcaaccac
      601 ttcgtttatc tgtcgcgcaa tatgagcatc actcttctgt cgtatagcaa gtggcgggct
      661 gacatgaata gtcagatgat gggtctttcc gtcataaaca gggaaaagcg gtattatccg
      721 tgcaccactg atcctgctga gccgtccgat aaccggtaaa gttgctttat acgtcgcaaa
      781 aaaatctgca aactcactga attccgggcc atgatcctga tcaggaagat aatatcccca
      841 gtatccctgc cggactgagc ggacaaagga ggcaataccg tcattacgtg cgtgcagttt
      901 tcctccgaaa cgacgacgaa cactgttcca gacataatcc accaccggat ttctctggtt
      961 atgaaacatc gctgccattt ttctgcccga cgcagctatc agcattgcgg gaatatccac
     1021 tccccaggca tgtggcacaa gaaaaatgac cttttcattg ttctgtgcca tcttctccac
     1081 aatctccaga ccattccagc gtatacgatg cgaaatttta tcaggcccgg acagtgctaa
     1141 ttcagccata agcacaacgg ccatggaggc tgttgcaaac atggcatcaa cgatattctc
     1201 cttttcttta tcactgtact ccggaaaaca aagcgataaa ttaatcaagg cccgttgacg
     1261 tgcgcttttc cccagacgcc caaccagcat gcccaatttt cccaacaatg gatctctcag
     1321 tgcggggggg accattgcaa acacacagat aataccgata cctgtccacg tcatccagta
     1381 acgggggaag cataatgtaa ggttaaagcg gggaataaac tcagttctga tatttttcat
     1441 atttaccggt atctgcctgc ttatctcatt atgataacag agtacagcag aaggtggtac
     1501 catccctgga gtccaccgga cagcagagga aaacacatcc tcctgccttc agaacggaac
     1561 cgaagataag aaaatactat ggctcaccat acggaagagt gtcgaaatca gtgagcccat
     1621 tctttttata cggatttcca atccagcggg tagtttccct gaattgcgga ttcaccagag
     1681 aacgggtcgg atcgtaacca tcgtatgtca gtcccgccaa atctgaccag gtgtggatca
     1741 gttcagccag actgtatttg cggtcaacat actgcgaaaa atctcgcgga tgtgcagcat
     1801 gccacttttc cgaggtccac agcaggaacg gaacagtgta catgggacgt gtggggttat
     1861 cttcattccg tccctgcgtt ttatatggcg gagtatcata tacttcttca ccatgatctg
     1921 aaaaataaag cagaaagccg tccggcgcag ttgctctgaa gtcctttatc agactggcca
     1981 ccacatgatc gttaaacaga ttggcattat cgtaatcgtt atacacttcc agctctttcg
     2041 catttaatcc agtgggaata tgccctgtaa tgccatcaaa ccgcccctga ccttccggat
     2101 aacggtattt atacttaatg tgcgtaccca gcagatgcac gatgatcagt ttctttggtg
     2161 cagggtcatt cagcacttcc cggaacggct tcagcacgtt agtgtcatat tcacgcgcac
     2221 tttgtgttcg ctgctgattc atgtagtact gcctgtccgt ctggcgcgaa aatacagtga
     2281 gcatggtgtt acgggctgtg attgtctgct ggttggtaat ccagaatgtt ttatagcctg
     2341 cctgcttcat catgttcatc agcgacggct gcgtcagata cagatcagga ttcttttcgt
     2401 tggcgaaagt aagggcctgt tgcaatgctt caatggtgta cggacgcgat gccaccacat
     2461 tattaaacac agtaagaccc ggatcggttt tacgcagtgc atccagctcc ggcgtcgttt
     2521 cacgtagata cccgtataag ctcatgcgtt cgcgctgtgt cgactcacca atcaccagga
     2581 ccagtgtgcg tggtctctcc cctgattcat ccctgagatt acccagtggt ggcagtgcgc
     2641 tattttcatt caggaaggtt gtcagtgcat tcagttgctg atggtactga taataactgg
     2701 atacaaactg ccagggggca gcaggctcca ttcgggatgc cagtttgcct agagtatcat
     2761 tcagcggctc ctgtctgatt aacgatttca gaacaaccgg atgcagaagc agagcataaa
     2821 gcagcaggaa agagacaatt ctccgccatg gcaaaggaat atatacagga cgcagacgtg
     2881 tccacagaaa aacggacacc gcagtatata ccagcgagat aagcaacagt ttaaggctga
     2941 aatactggct gaaatattca ccagcctctc tggcattcgt ttcaaacata acgaaaagaa
     3001 cactttgaga gaattcatga ccatagagaa aataataaca aagtgctgcc agcgacgtgc
     3061 cccagagaat gaaaccgaca acagctgcaa ttatttttat ccgatcagga tagagaaaca
     3121 ccgggatcaa ccacagacaa ctgaataaca gtgagtcccg tattccattc gttccgctgt
     3181 acccactgct gaagatgatg acctgcagga gagtggaaaa aaagccaaaa taaaaaattg
     3241 cccatcccag cgcactccag ctgaaagtag gcctgttctg tccggtattt aaatgcattg
     3301 accgtccccg tatttaaaca atgtgataaa ttactccgtt acttgccgga aaaccgctga
     3361 acaaaattcg ggctgaaaag aggatccgcc gttatctgtt acatttcccc ttagcctgac
     3421 tagccagaga cacaatgatc tgtgccgttc tgttaatatc aaaccggtac tcaatatctt
     3481 ctctggcgct ggctgccatc atccggaagc gttccggtcg ggataaaaaa tcgcgcagtg
     3541 cgccggtcca tgcagacaca tcccccacgg gtaacagcgt ccctgtcaca ttcttctgaa
     3601 tgacatcagg gatcccgccc gtctcactgg cgataacggg cacgccagag actgacgctt
     3661 cagccagtac cataccaaac gcttcatttt ccgaaggcat gaccaccaca ctggcaatcc
     3721 ggtagaccgg taacgctggg aaaagggcac ctgccattaa cacatctccg ctcattccca
     3781 ggtgttctgt ctgctgacgc agacgtgctt cgtattcttc acgcccggcg cccaccacga
     3841 gccagcgaaa tgatttccct tccatcttca gctgatacaa tacacgcagc ataaattcat
     3901 gtcctttttc gggacgtagc atccccacct gaacgataag cggaacattg tctgctgatg
     3961 cagcccaggc gtggatatgc aggggtaacg gtcgcatggc ttcattatgc aatgcgggcc
     4021 agtcgaaacc cggtggaata accgttaccg gtgtcctgac accttccgcc atcagatgcg
     4081 ccatcatggc tgagctaggc acaacaatga aatcacacag ataattcagg gaaaacgttc
     4141 gggtcttacg ggtgatgtag gttttttgtc tgacaatact gaagcggtga cagcatatca
     4201 gacggctcag tcctgctata ttactgtcat ggccactatg gcagatgacc agatcaggtt
     4261 taaattcccc gataatccgt cgaagtctga ggatggaagg aaggtgaagg ctgttcctga
     4321 aaggaataaa agtgacatca tgccctcttt ttctggcttc cggagcaatt ttactttttt
     4381 ccctgcaggc aagtaaaacg gaatgtccct gcttttgaag agcagtcatc tgggccagtg
     4441 cctgcagctc ctggccccca atatctgacg aagattcagt gaataaaatt ttcatcatta
     4501 attatctggt aatcttggcc ccttatgaag agccagtact gaagaaaaaa gtggcgttgt
     4561 ataataaaaa aggcgtcgtt tcagccagcc ggaatgttcc cgctctttgg tgctgatacg
     4621 ccctatgcgt aatgaaccat tttcaggaca gttcattctt ctttcggttg tatataaata
     4681 agagaaacca agcttaccgg cgagattaat ataatcccga ttataatatc cttcaggcca
     4741 gcacagatgg gaactacaga accccagctt ttccgtcaga cattgttttc ccaccagaat
     4801 atcttctttc atgagccggc actgttcagc acgtgataca gacaacctgt cccagcgttt
     4861 atgtgaatgg gtgtgcacat gaaattcaac cagtccggaa tcacgcattt cccggacttc
     4921 agaccagcga agcatgacct catctgaacg gttatcggca atcaaccgtt cacagtcgcg
     4981 gtgagaatat tcctgctcct gcctgctacg tacgtttccc ttaccaatca gccccgtaat
     5041 gagaaaaata tgtgcatgaa ggttatattc cttcaggacc ggccatgctc tgagccagtt
     5101 atcaagataa ccatcatcga atgtgagcat gacactcttt cgtggaagcg ttcccccctg
     5161 ataaaaatat tcaagctcag cagatgttac cgtccgccag ttattatctg cgagccactt
     5221 catctgttca caaaatgttt caggtgagag tgtcacaagc cccggacaac gactgacatg
     5281 atgatacatc agtacgggaa gatgccttgc attcaacata aaaaattatc gtctgttaag
     5341 cattctgaaa atatcctcgc gtaaacaaca gtgaggatcc atagatatca cacatggtga
     5401 tattattgtg taatcccgga atggtccgga gattaccgac aacagggatt ttttaatatt
     5461 tttatcagtt aatcaaccag aacttaaatt tcccttaacg catatgctct ttttaatcag
     5521 attttctgtt tttcagaaaa aacagaatac cgcaatttca gtaaacacag cgagagatat
     5581 ccgcctcagt aaaaaatcag aagattatca tcctgattta ttgcataaaa ccagtcgagt
     5641 agcggaattt tctgcatccg gataccactc cccctgaaaa atactcgcac aatatcgcgc
     5701 cgcatgcact gatggaccgg gccatcgtga gaatctcttg catcgtagat attaaccaca
     5761 ccagtgcccc ccagaacaac agtaatacct gtagcagacc tgccatagag gttaaataac
     5821 cattcatatc cctcttctac ccattcatcc cgaagtttca gccagcgacg aatggactgt
     5881 acctcctgtt tcagccgagg ggctgagttg acaaaccgtt tagagccgcc ggatattcag
     5941 gttaccggcc tgcaaatcaa tatcagacag ttttatacct aataactctg atgcttgtac
     6001 accatgaaga taccccataa ggagcaggca gtgattacgt tccgggtgtg gcactttgaa
     6061 gacagcactg tgcaacttat gaatctcacc cgggttcaga tatttttgtt gtccattacc
     6121 tgtccttatt tattgaaagt cgatattagt ttaaaaagct gctaatcatg acaccattac
     6181 agaagtaaaa ttaatttatt ttaaatacat aaaattattg ttcatttatt tttttgcgaa
     6241 cattcataaa ctaaaaaaac aatggataaa accaataaca ttgcataata atacacctcc
     6301 cttataaata atggagaaga aaatgaaaag gcggtatatc acctatgctg aacctgttta
     6361 ggatgctgtg taaatgcctt ttctccgaag tgaccgtcca agcggtcacc gaattcgata
     6421 ataaagcggc tcattgccat acaccagtcc ttcaacggca tcgtccattt ctgaggcgca
     6481 gactggatag ctaaagtgta gcggtattag gagctgttat ttagttcgaa tatcgaaaat
     6541 ttttgtgtac gttggtcgta tcaatctctt tttatttgaa ttagtttgat aacagatttt
     6601 tgcaatctga taactcattt atttattgag ggataaatgc aatgttgtac aatatgtttc
     6661 cgccattagc aaaagaatcc acaaggcgct tgcactaatg catggtaatg cctccaatta
     6721 gttgaattag gggtat
//
LOCUS       DAZUDJ010000145         6446 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.147, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000145 DAZUDJ010000000
VERSION     DAZUDJ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6446
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.147"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..1856)
                     /locus_tag="ACHY1N_004843"
     CDS             complement(<1..1856)
                     /locus_tag="ACHY1N_004843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HFS4046994.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPIEGPVEGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETNSKGDRNPSQVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGSGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKAWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPNNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISTGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGQGNPVSVEVQSVTDGLKVKVNRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPP"
     gene            complement(1917..2489)
                     /locus_tag="ACHY1N_004844"
     CDS             complement(1917..2489)
                     /locus_tag="ACHY1N_004844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309674.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HFS4046995.1"
                     /translation="MKTGAEAIRALATQLPAFRQKLSNGWYQVRIAGRDVSTSGLTAQ
                     LHETLPDGAVIHIVPRVAGAKSGGVFQIVLGAAAIAGSFFTAGATLAAWGAAIGAGGM
                     TGILFSLGASMVLGGVAQMLAPKARTPTAASTDNGKQNTYFSSLDNMVAQGNVLPVLY
                     GEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            complement(2486..3229)
                     /locus_tag="ACHY1N_004845"
     CDS             complement(2486..3229)
                     /locus_tag="ACHY1N_004845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFS4046996.1"
                     /translation="MTETESAILAHARRCAPAESCGFVVRTPEGERYFPCVNISGEPE
                     DYFRMAPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGAIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHRGDDWWRNGQNLYLDNMEAT
                     GFYRVALTEAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWRASAFTGIYNDLAAASTFV"
     gene            complement(3235..3933)
                     /locus_tag="ACHY1N_004846"
     CDS             complement(3235..3933)
                     /locus_tag="ACHY1N_004846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030430 - host cell cytoplasm [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HFS4046997.1"
                     /translation="MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQAYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDLQSLVGGT
                     VVRRKVYARFLDAVNFVNGNIEADPEQEVISRWRIEQCSELSAASASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYSGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            complement(3933..4262)
                     /locus_tag="ACHY1N_004847"
     CDS             complement(3933..4262)
                     /locus_tag="ACHY1N_004847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4046998.1"
                     /translation="MKTFRWKVKPGMDVASAPSVRKVRFGDGYSQRAPAGLNANLKTY
                     SVTLSVPREEATVLESFLEEHGGWKAFLWTPPYEWRQIKVTCAKWSSRVSMLRVEFSA
                     EFEQVVN"
     gene            complement(4259..>6446)
                     /locus_tag="ACHY1N_004848"
     CDS             complement(4259..>6446)
                     /locus_tag="ACHY1N_004848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4046999.1"
                     /translation="TSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQSGLTADRMLL
                     LSRAGQAAGLTFNQTSESLSALVKAGVSGEAQIASISQSVARFSSASGVEVDKVAEAF
                     GKLTTDPTSGLTAMARQFHNVTAEQIAYVAQLQRSGDEAGALQAANEAATKGFDDQTR
                     RLKENMGTLETWADSTARAFKSMWDAVLDTGRPDTAQEMLIKAEAAFKKADDIWNLRK
                     DDYFVNDEARARYWDDREKARLALEAARKKAEQQSQQDKNAQQQSDTEASRLKYTEEA
                     QKAYERLQTPLEKYTARQEELNKALKDGKILQADYNTLMAAAKKDYEATLKKPKQSGV
                     KVSAGDRQEDSAHAALLTLQAELRTLEKHAGANEKISQQRRDLWKAESQFAVLEEVAQ
                     RRQLSAQEKSLLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFAQQQRAKRAA
                     IDAKSRGLTDRQAAREATEQRLKEQYGDNPLALNNVMSEQKKTWAAEDQLRGSWMAGL
                     KSGWSEWKESATDSMSQVKSAATQTFDGIAQNMAAMLTGSEQNWRSFTRSVLSMMTEI
                     LLKQAMVGIVGSIGSAIGGAVGGGASASGGTAIQAAAAKFHFATGGFTGTGGKYEPAG
                     IVHRGEFVFTKEATSRIGVGNLYRLMRGYATGGYVGTPGSLADSRSQASGKFEQNNHV
                     VINNDGTNGQIGPQALKAVYDVARKAAMDVVTGQMRDGGLFSGGGR"
BASE COUNT         1258 a         2125 c         1613 g         1450 t
ORIGIN      
        1 ggcggcgtga caccattcac cgtgccgctc tggtcgccgt caaagtgcgc cccgttatcc
       61 acgatggctt ctttttccgg tacatgctgc acggcagtga tggcatacgt gccgtcatcg
      121 ttctcacgga tactcacgca gcggaacagg cgctgacgca acgtcggcaa cttcagcccc
      181 cacacactgt attctgcaac gccgtcagga acccggttca ctttcacctt aagtccgtcg
      241 gtgacggact gaacttccac gctgaccgga ttaccctgcc cgtcaaccag gcttatcagc
      301 gtggtaccgg aggatggcag cgtgatttca cggtcgagcg tcagcgtccg ggtctggctg
      361 ttcaccgcca gcacgcgacc accggtgctg ataccggcat agtcatcatc gcagatttca
      421 atgacatcgc ccggtacatg gcgaagccct tcagcaccca cgctgaaatc cacggtctgc
      481 gtctccagca gttccgtttt aatcagccac agcccggcgc ggtgtgcctg cccccggctg
      541 gtacagccaa aggcatccat cttcgtgaca ttacgaccgt aacgggcaat ggcctgcgta
      601 tcctccacga gctctgtcgc cgtctcccag ccgttgttcg ggtcaatcca gttcacctca
      661 acggcattat ggcggtcttt cagggcgctg aagctgtagc ggaacggcgc gccatcatcc
      721 ggcatcacca cattactgcg gttataggtc cacgccttat ccgacggtcg gtcctgcacg
      781 aacgtcagcg tctgcccgtt ccataccggc atacagcgca tcgccgagca gaaatcactg
      841 agaacgtccc acgccttgcg ctgtgtggtc aggtacgcat tacaggtgat gcgcggctcc
      901 gtgccgccag agccgtccgg cactgactgg tcgcagtact ggccgatgac atacagcgcc
      961 catttgtcca catccgccgc accaagacgt ttccccatgc cgtagcgtgg atgggtcagc
     1021 atatcccaca gacaccaggc catgttattg ctgtatgctg gcttaaacgt tccgtcccag
     1081 ataccgctgt attgccgcgt ctgcgggtta tagttcgacg gcacctgcag aatgcgcccg
     1141 cgcagatgat aattacgact cacctgctgg ctgccgaact gctccgaatc cacctgcacg
     1201 ccgaccagtg ccgtgttcgg gtagcactgt ttcacatcga tgatttcggt gtatgacgac
     1261 cagagcgttt tgttctgcag ctggtctgtg gtgctgtccg gcgtcattct gcgcatccgg
     1321 atattaaacg ggcgcggcgg caggttatcc accaccaccg aggccagata ctgtgaggtg
     1381 gttttgccct taatggtgat gtctttttcc gtcacccagc caccgttacg ctgtatctga
     1441 accagcaggc gaacctgcga tggattcctg tccccctttg agttggtttc caccagtgcc
     1501 tgcacaccga aggtaaagcg cagacggtcg atgtttgccg acgtgatggt ccgggttatc
     1561 ggcgtgtcat atttcacttc cgtacccagc accgtctcgg agccggagga ttcaaaccct
     1621 tcaggcggtg tctgctcctg ctcaccggcc cggaacacca ccgtgacgcc ggagatattg
     1681 gtattcccct cactgtccag caccggcgta ctgttcagca gcacgctttt taatccctcc
     1741 accggacctt caatcggtcc ttcactgatg gcatcaatca cactcagtaa ctgcgtggat
     1801 ttcaggttgt ccttcgcttc gcgcggggta tgccccttac tgctgccttt acccattcct
     1861 cactctccag aaacgataaa accgcccgca ggcggtttca cataaaatgt tttgcatcag
     1921 cgaccaatca ccacaacctg accaccgtcc ccttcgtctg ccgtgcttat ctcctgagaa
     1981 accacacgtg accccacgcg catttcaccg tacagaacag gcagaacatt gccctgggca
     2041 accatgttat ccagtgagga gaaataggtg ttctgtttgc cgttatctgt acttgctgcc
     2101 gtgggcgtcc tggctttcgg tgccagcatc tgcgccacac caccgagcac catactggca
     2161 ccgagagaaa acaggatacc ggtcatacca ccggccccaa tggctgcccc ccatgctgca
     2221 agggtggctc cggcagtaaa gaatgatccg gcaatggcgg cagcccccag aacaatctgg
     2281 aatacgccac ctgacttggc cccggcgact ctgggaacaa tatgaatcac agcgccgtca
     2341 ggcagagtct catgtaactg cgccgttaac ccggacgtgc tgacgtcccg cccggcaatc
     2401 cgtacctgat accagccgtt gctcagtttc tgacgaaacg ccgggagctg tgtggccagt
     2461 gcgcggatag cttcagcccc cgttttcaca cgaaggtcga tgcggcggcc aaatcgttgt
     2521 aaatccccgt aaaggcggat gcgcgccatg cccggtgacg ccagagggag tgtgtgcgtc
     2581 gctgccattt gtcggtatac ctctctcgtt tgctcagttg ttcaggaata tggtgcagca
     2641 gctcgccgtc accacagtaa atggcggcat gattcggcac cgatgaacca aaacagcaca
     2701 gcagcacgtc gccaggctgc gcctctgtca gtgcgacacg gtaaaaacca gtcgcctcca
     2761 tattgtcaag atagagattc tgaccgttac gccaccagtc atccccgcga tgaaaatccg
     2821 gcatctcaat ccccgccaga tgataagcat cccggaacag cgtgtaacag tccgtcaccc
     2881 cgtgctcaaa gcgacgcccg gtgagatgcg gcacacagcg gaacttgtga atcgcccccc
     2941 ggcagaccag ccaccacggc aaatcactct gcacctgcag ccgccggtca gcctcactca
     3001 gccagggcag accaccggga tgactgtgga ccagtgccac aatctcaccc tgcatctctg
     3061 cctgcagcca gtcctccgga gccatccgga aataatcctc cggctcaccg gaaatattca
     3121 cgcagggaaa atatctttcc ccctccggcg ttcttaccac gaagccgcac gactccgctg
     3181 gcgcacatcg ccgggcgtgc gccagaatgg ctgattctgt ctctgtcatg ggattcactg
     3241 cgaaagtttg ttaatggaaa ggaagccgcc aaagttgccg acgttattgc gaaacttaca
     3301 gccgctcagg catttgctgc atttatcctt cgtgatatcg gacgtcggct ggtcatattc
     3361 atccgcgacc gccggaccgc tataaccgca ctcatcgccg cgataggtcc aggtgcaggt
     3421 gttggccagc atgatacgcc ccggaaaaac agcgccgtcc gtttccgtcg gtgtggacag
     3481 tacaaaagag gcactggccg cgctcagttc gctgcactgc tcgatgcgcc agcggctgat
     3541 cacctcctgc tccgggtctg cctcgatgtt tccgttgacg aagttcaccg catccagaaa
     3601 acgggcgtaa accttacgcc ggaccaccgt tccgccgacc agactctgca gatcttccgc
     3661 catcccggtg accataccgt acaggttaga aaccgtcagc gtgggccgcg tactggtgcc
     3721 tttgccattc agttcaaaac cgctcccctg aatgggatac gcctgatact gcctcccctg
     3781 ccaggtgacc ggctcacctt tttcgttctg ctcattacag aaaaaataac gttctccacc
     3841 gacctctgtc agatcgattt cccagagcac cacgctggcc gactgctccg cacgggtgca
     3901 ttcattcagc gtttcctgcc ggatatcctg catcagttca ccacctgttc aaactctgcg
     3961 ctgaactcaa cacgcagcat actgacccgc gacgaccatt ttgcgcaggt cacctttatc
     4021 tgccgccact cataaggcgg cgtccacaga aaggctttcc agcccccgtg ctcttccaga
     4081 aacgactcca gtaccgtggc ctcctcacgg gggacagaaa gcgtcacgct gtacgttttc
     4141 aggttggcat tcagcccggc aggcgctcgc tgggaatagc catcaccaaa gcgcaccttt
     4201 cttacagaag gggccgaagc cacatccata ccgggtttca ctttccagcg gaaggttttc
     4261 atcgtccacc tccggagaac agaccaccat cacgcatctg cccggtcaca acatccattg
     4321 ccgccttacg ggctacgtca taaaccgcct tcagcgcctg tggccctatc tgaccgttcg
     4381 tgccgtcgtt gttaatcacc acatggttat tctgctcaaa cttcccggac gcctgcgacc
     4441 ggctgtccgc cagactgccc ggtgtaccga cataaccgcc ggtggcatag ccgcgcatca
     4501 gccggtaaag attccccacg ccaatccggc tggttgcctc cttcgtgaag acaaactcac
     4561 cacggtgaac aatccccgct ggctcatatt tgccgccggt tcccgtaaat cctccggtcg
     4621 caaaatggaa tttcgccgca gctgcctgaa tggctgtacc gcctgatgcg gatgcgccgc
     4681 caccaacagc cccgccaatg gcgctaccga tactcccgac aatccccacc attgcctgct
     4741 taagcagaat ttctgtcatc atggacagca cggaacgggt gaagctgcgc cagttctgct
     4801 cactgccggt cagcatcgcc gccatattct gcgcaatacc atcaaaggtc tgcgtggcag
     4861 cacttttaac ctgcgacata ctgtccgtgg cactctcttt ccactcgctc cagccggact
     4921 tcaggcctgc catccagctc ccgcgaagct ggtcttcagc cgcccaggtc tttttctgct
     4981 ctgacatgac gttattcagc gccagcggat tatcgccata ctgttccttc aggcgctgtt
     5041 ccgtggcttc ccgcgctgcc tgccggtcag tcagcccccg gcttttcgca tcaatagctg
     5101 cccgttttgc ccgttgttgc tgtgcgaatt tatccgcctg ctgcgccagc gcattcagac
     5161 gctcctgata cgtcaccttg tcgccaagtg ccgccagctg gcgtttgtac tccagcgtct
     5221 cgtctttatg cgccagcagg gatttctcct gtgcggatag ctgacgacgt tgtgccacct
     5281 cctccagtac cgcgaactga ctttctgcct tccacaaatc ccggcgctgc tggctgattt
     5341 tctcattcgc tccggcatgc ttctccagcg tccggagttc tgcctgaagc gtcagcaggg
     5401 cagcatgagc actgtcttcc tggcgatcgc ctgcagacac cttcacgccg gactgtttcg
     5461 gctttttcag cgtcgcttca taatcctttt tcgctgccgc catcagcgtg ttgtaatccg
     5521 cctgcaggat tttcccgtct ttcagtgcct tgttcagttc ttcctgacgg gcggtatatt
     5581 tctccagcgg cgtctgcagc cgttcgtaag ccttctgcgc ctcttcggta tatttcagcc
     5641 gtgacgcttc ggtatcgctc tgctgctgcg catttttgtc ctgttgactc tgctgttcag
     5701 ccttctttct ggcggcttca agcgcaagac gggccttttc acgatcatcc cagtaacgcg
     5761 cccgcgcttc atcgttaaca aaataatcat ccttgcgcag attccagatg tcgtccgctt
     5821 tcttaaacgc agcctctgcc ttaatcagca tctcctgagc ggtatcagga cgaccagtat
     5881 ccagcaccgc atcccacatg gatttgaatg cccgtgctgt gctgtctgcc caggtctcca
     5941 gcgtgcccat gttctctttc aggcggcggg tctggtcatc aaaccctttc gttgcggcct
     6001 cgttcgccgc ctgcaatgcc ccggcttcat cgccggaacg ctgcaactga gcaacatacg
     6061 caatctgctc cgccgtcacg ttatggaact gacgcgccat cgctgtcagc cccgacgtcg
     6121 ggtctgtggt cagcttcccg aaggcttcag cgaccttgtc cacctccacg ccggatgcag
     6181 aggagaaacg cgccacactc tggctgatgg atgcaatctg agcctcaccg cttactcccg
     6241 ccttaaccag tgcgctgagt gactcgctgg tctggttaaa cgtcagccct gccgcctgcc
     6301 cggctctgga caggagcagc atacgatctg ccgtcagacc cgactgattg ccggaaagga
     6361 ccagcgtttt gttgaaatcg gacagggttg agttgccctg ataccaggca tacgccagcg
     6421 caccggtcgc caccgccagc gaggtg
//
LOCUS       DAZUDJ010000146         6358 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.148, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000146 DAZUDJ010000000
VERSION     DAZUDJ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6358
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.148"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(171..2204)
                     /gene="betT"
                     /locus_tag="ACHY1N_004849"
     CDS             complement(171..2204)
                     /gene="betT"
                     /locus_tag="ACHY1N_004849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HFS4047000.1"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA"
     gene            2333..2920
                     /gene="betI"
                     /locus_tag="ACHY1N_004850"
     CDS             2333..2920
                     /gene="betI"
                     /locus_tag="ACHY1N_004850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308386.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BetI"
                     /protein_id="HFS4047001.1"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAEQRLQAIVAGNFDETQVS
                     SAAMKAWMAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPREQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD"
     gene            2934..4406
                     /gene="betB"
                     /locus_tag="ACHY1N_004851"
     CDS             2934..4406
                     /gene="betB"
                     /locus_tag="ACHY1N_004851"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008802 - betaine-aldehyde dehydrogenase
                     (NAD+) activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0019285 - glycine betaine biosynthetic
                     process from choline [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HFS4047002.1"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETLFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTE
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGDVLKGDGFDNGAWVAPTVFTDCRDEMTIVREEIFGPV
                     MSLLTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     gene            4420..6108
                     /gene="betA"
                     /locus_tag="ACHY1N_004852"
     CDS             4420..6108
                     /gene="betA"
                     /locus_tag="ACHY1N_004852"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008812 - choline dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0019285 - glycine betaine biosynthetic
                     process from choline [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HFS4047003.1"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEA
                     MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GTECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPVRAKKMSRDVN"
BASE COUNT         1569 a         1741 c         1733 g         1315 t
ORIGIN      
        1 gctaatacaa aataaaatcg ttaattaata aaatataaaa tcatgaagtg atacaagagg
       61 aattgcagga tatgacatga caatcatata taatatatgc ataatttttt acagcgagtc
      121 aatgattccc gcgccatatg cagacatggc gcggttttat gcaaaaacaa tcacgcgtcc
      181 gggaacatca cgctatggcc cggcgcttca cgatggagat gaataaagtt aaggtgccgc
      241 tcgtactggt caagaatatc ggtgatcacc tgctctttgc tgtagtccat caggtcgttg
      301 ccctggctgc cttctaacag gaaggtttcc agccggtagt aggtcgattt accgctacgt
      361 gcgcggtagg taaagcccgg caccgaatat tgctgcggcc aaatctgata gacaaagttt
      421 tgttcttcgc ccatatgcac caacaaatcc agatgcccca actgttgtcc ctcttccggc
      481 ggcaggcttt ttagctccac gtatgcgccg cgcaaccgca gctcctgcgc cacttcttcc
      541 attgccgggt aacagaccgt ctccatcatc tgtttagtgt aacgcgtgcc cggataattc
      601 atcaggcgcg agagacgttt tttccagctc aggcgatcct gaagccccag cggtcgcggt
      661 gcggtatcgc ggttggcact ttcacggcgg taatcttcta ccttcagaga tttatacaac
      721 cccgccatca cgaagaagat cacaaagctg aacggcagcc ccataatcac cgtggtgttt
      781 tgcagcgcgg atatcccgtt ggtcatcagc atgccgagcg tcagcaggcc aatcgccacc
      841 gaccagaaga cgcgcagcca gccgggggcg tcgctgttga tatctttaag ctgcgaggtg
      901 aaattcccca gcaccagcgc accggagtcc gccgaggtca cataaaacag caggccagta
      961 atggtggcga cggaggcgct aaaggtaaac gccggatact gcgccagcag gctgtaaaag
     1021 ccgcgctccg gatggaccat cgcttcctcg gcaaatgccg cgccgccgtg gatgatttca
     1081 tacagcgcgc tattgccgaa caccgagagc cataacagcg tgaaggtaaa cggaataatc
     1141 aacgtgccca gcacgaactg gcgaatggta cgcccacgcg agatacgcgc caggaacaag
     1201 ccgacaaacg gcgaccatgc cacccaccat gcccagaaga agagcgtcca gttattcatc
     1261 cactcaactg gacggtcgaa ggcaaaactg ttgagcgtca tgcccataaa gcgattcaca
     1321 tagtcgccaa cattcagcac cagcgcatta agcaggaacg aggtgtcgcc cataaacaat
     1381 acgaacagga tcaatcccag cgccagcgca acgttaagtt ccgataacac acgaatcccc
     1441 ttatcgacac cggaggtgac agagatcgtg gcgattatca ccgacaaggc gatcagtgcc
     1501 gcttttgccg ccatcgaatc gggaatatca aacagtacgc tcaagccata gttaagctgc
     1561 accacaccga taccgagcgt agtggcaata ccgaagatgg tgccgatcac cgctgcaata
     1621 tccactgagt gccctatcgg cccgttaatc cgtttaccga agatcgggta cagcgccgag
     1681 cggatggtga gcggcaaatt ataacgatag ctaaagtatc cgagcgccat gcccatcagc
     1741 gcatacatcg accagccggt taagccgtag tgaaacagcg tccagaccat cgcctgacgc
     1801 gcggcctcaa tcgtctgtcc cgcgccttcc ggcggctgca tatactgcgt taccggttcg
     1861 gctacggaga agaacatcag gtcgataccg atcccggcag caaacagcat cgccgcccaa
     1921 ctcagcaggc tgaattccgg tttggattgt tctggcccga gcttcaccga accaaaacgc
     1981 gaacaagcga tacagaccac aaagacaata tagagcgttg ccgccagtag atagtaccaa
     2041 ccgaaggttt tagaaaccca gtccagcgtg cggccaatcc acagggccga gaagtcgcga
     2101 aacaggatcg ttgtcaggga aaacaacaaa atcagtccgg cggaggtgta aaacaccacc
     2161 ggattgattt tgtccttttc cctgctgtgt gaaaggtctg tcatccagta tccccactgt
     2221 tattgttacc atttaaaatc aaattcgtaa caattaagac acattttata ttgaacgtcc
     2281 aatcaataac cgctttaata gataaacaac gctgatgaat ggagtggcga aaatgcccaa
     2341 attggggatg cagtcgatcc ggcgcagaca actgatcgac gccacactgg aagcaataaa
     2401 tgaagtgggc atgcacgatg caacgatcgc gcagatcgcc cgccgtgcag gcgtttctac
     2461 ggggatcatc agccactatt tcagggacaa aaatggtctg ctggaagcaa ccatgcgcga
     2521 catcaccagt cagttacgtg acgcggtttt gaatcgatta catgcacttc cgcagggcag
     2581 tgcagagcag cgattacagg cgattgttgc cggaaacttc gatgaaactc aggtgagcag
     2641 tgcggcgatg aaagcctgga tggcgttctg ggccagcagt atgcatcagc cgatgctcta
     2701 tcgtttacag caggtcagca gccgccgctt gctgtcgaat ctggtgagcg agtttcgccg
     2761 cgaattgccg cgcgaacagg cacaggaagc gggctacggc cttgccgcgc tgattgacgg
     2821 attatggctg cgcgcggcac tgagcggcaa accgctggat aaacctctcg cacactcgct
     2881 gacccgtcac tttattactc agcatttacc caccgattaa ccgaggagac gtgatgtccc
     2941 gaatggcaga acagcagctt tatatacatg gtggttatac ctccgccacc agcggtcgca
     3001 ccttcgagac cattaacccg gccaacggta acgtgctggc gaccgtgcag gccgccgggc
     3061 gcgaggatgt cgatcgcgcc gtgaagagtg cccaacaggg gcaaaaaatc tgggcggcga
     3121 tgaccgctat ggaacgctcg cgtattctgc gtcgggccgt tgatattctg cgtgaacgca
     3181 atgacgaact cgcaaaactt gaaaccctcg acaccggaaa agcatattcg gaaacctcaa
     3241 ccgtcgatat cgttaccggt gcggacgtgc tggagtacta cgccgggctg atcccggctc
     3301 tggaaggcag ccagatcccg ttgcgtgaga cgttatttgt ttatacccgc cgcgaacctc
     3361 tgggtgtggt ggcggggatt ggcgcatgga actacccgat tcagattgcc ctgtggaaat
     3421 ccgccccggc gctggcggca ggcaacgcaa tgattttcaa accgagcgaa gtcaccccgc
     3481 ttaccgcgtt aaagctggct gaaatttaca gcgaagcggg cctgccggac ggcgtattta
     3541 acgtgttgcc gggggtgggc gcggagaccg ggcaatatct gaccgagcat ccgggcattg
     3601 ccaaagtgtc atttaccggc ggtgtcgcca gcggcaaaaa agtgatggct aactcggcgg
     3661 cctcttccct gaaagaagtg accatggaac tgggcggtaa atcaccgctg atcgttttcg
     3721 atgatgcgga tctcgatctc gccgccgata tcgccatgat ggcaaacttc ttcagctccg
     3781 gtcaggtgtg taccaatggc acccgcgtct tcgttccggc gaaatgcaaa gccgcatttg
     3841 agcagaaaat tctggcgcgc gttgagcgca ttcgcgcggg cgacgttttc gatccgcaaa
     3901 ctaacttcgg cccgctggtc agcttcccgc atcgcgataa cgtgctgcgc tatatcgcca
     3961 aaggcaaaga ggaaggcgcg cgcgtactgt gcggcggcga tgtactgaaa ggcgatggct
     4021 tcgataacgg cgcatgggtt gcaccgaccg tgttcaccga ttgccgcgac gaaatgacca
     4081 tcgtgcgcga agagatcttc ggtccggtga tgtcgcttct cacttatgaa tctgaggacg
     4141 aagtgattcg ccgcgccaat gataccgact acggcctggc ggcgggcatc gtgacggcgg
     4201 acctgaaccg cgcgcatcgc gtcattcatc agctggaagc gggtatttgc tggatcaaca
     4261 cctggggcga atccccggca gagatgcccg ttggcggcta caaacactcc ggcattggtc
     4321 gcgagaacgg cgtgatgacg ctccagagtt acacccaggt gaagtccatc caggttgaga
     4381 tggctaaatt ccagtccata ttctaaccag gaggtttatt tgcaatttga ctacatcatt
     4441 attggtgccg gctcagccgg aaacgttctc gctacccgtc tgactgaaga tccgaatacc
     4501 tccgtgctgc tgcttgaagc gggcggcccg gactatcgct ttgacttccg cacccagatg
     4561 cccgcagcgc tggcgttccc actacagggc aaacgctaca actgggccta tgaaacagag
     4621 cctgaaccgt ttatgaataa ccgccgcatg gagtgcggac gcggtaaagg cctgggtgga
     4681 tcgtcgctga tcaacggcat gtgctacatc cgtggcaatg cgctggatct cgataactgg
     4741 gcgcaagaac ccggtctgga gaactggagt tatctcgact gcctgcccta ctaccgcaag
     4801 gccgagactc gcgatgtggg cgagaacgac taccacggtg gcgatggccc ggtgagcgtc
     4861 accacctcca aacccggcgt caatccgctg tttgaagcga tgattgaagc gggcgtgcag
     4921 gcaggctacc cgcgcacgga cgatctcaac ggctatcagc aggaaggttt tggcccgatg
     4981 gatcgcaccg tcacgccgca gggccgtcgc gccagtaccg cgcgcggtta tctcgatcag
     5041 gccaaatcgc gccctaacct gaccattcgt actcacgcta tgaccgatca catcattttt
     5101 gacggcaaac gcgcggtggg cgtcgaatgg ctggaaggcg acagcaccat cccaacccgc
     5161 gcaacggcca acaaagaagt gctgttatgt gcaggcgcga ttgcctcacc gcagatcctg
     5221 caacgctccg gcgtcggcaa cgctgaactg ctggcggagt ttgatattcc gctggtgcat
     5281 gaattacccg gcgtcggcga aaatcttcag gatcatctgg agatgtatct gcaatatgag
     5341 tgcaaagaac cggtttccct ctaccctgcc ctgcagtggt ggaaccaacc gaaaatcggt
     5401 gcggagtggc tgtttggcgg cactggcgtt ggtgccagca accactttga agcaggtgga
     5461 tttattcgca gccgtgagga atttgcgtgg ccgaatattc agtaccattt cctgccagta
     5521 gcgattaact ataacggctc gaatgcagtg aaagagcacg gtttccagtg ccacgtcggc
     5581 tcaatgcgct cgccaagccg tgggcatgtg cggattaaat cccgcgaccc gcaccagcat
     5641 ccggcgattc tgtttaacta catgtcgcac gagcaggact ggcaggagtt ccgcgacgca
     5701 attcgcatca cccgcgagat catgcatcaa cccgcgctgg atcagtatcg tggccgcgaa
     5761 atcagccccg gcacggaatg tcagacggat gaacagctcg atgagttcgt gcgtaaccac
     5821 gccgaaaccg ccttccatcc gtgcggtacc tgcaaaatgg gttacgacga gatgtccgtg
     5881 gttgacggcg aaggccgcgt acacgggtta gaaggcctgc gtgtggtgga tgcgtcgatt
     5941 atgccgcaga ttatcaccgg gaatttgaac gccacgacaa ttatgattgg cgagaaaata
     6001 gcggatatga ttcgtggaca ggaagcgctg ccgaggagca cggcgggata ttttgtggca
     6061 aatgggatgc cggtgagagc gaaaaaaatg agtcgtgatg tgaactgact caagaaccga
     6121 tcagattgag agttaccgtt ccaggcatgg ggacagaatc gttatataaa acataggggt
     6181 aactctcatg cttcatatcc agtattcatg atgctggctt tttgctgata tttaacccga
     6241 acattcctga tacagactat taatacaacc ttatctgcga cagattttat tttctggata
     6301 tattatgcgt gaacaaatca aacaggatat cgatctgatt gagattttat tttatctg
//
LOCUS       DAZUDJ010000147         6323 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.149, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000147 DAZUDJ010000000
VERSION     DAZUDJ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6323
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.149"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..427)
                     /gene="sepD"
                     /locus_tag="ACHY1N_004853"
     CDS             complement(<1..427)
                     /gene="sepD"
                     /locus_tag="ACHY1N_004853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE switch protein
                     SepD"
                     /protein_id="HFS4047004.1"
                     /translation="MNNNNGIVKNDSDWLTALDFVKDVKGSPKHLTFHIYQKNAFLHD
                     FGSYWVLYIELNGDFRQVPTDTFIRLCNILAVSKEYKQMGIFQSNKKWYLCQLFNKDN
                     NHRANMSKAIMQHTLASLLDKQFDKLEQASTSDTTMPPTH"
     gene            complement(433..1005)
                     /gene="escJ"
                     /locus_tag="ACHY1N_004854"
     CDS             complement(433..1005)
                     /gene="escJ"
                     /locus_tag="ACHY1N_004854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE inner membrane
                     ring protein EscJ"
                     /protein_id="HFS4047005.1"
                     /translation="MRKYIKNTFLFVFICLTVACKEQLYTGLTEKEANQMQALLLSND
                     VNVSKEMDKSGNVTISVEKEDFVRAITILNNNGFPKKKFADIEVIFPPSQLVASPSQE
                     NAKINYLKEQDIERLLSKIPGVIDCSVSLNVNNNESQPSSAAVLVISSPEVNLAPSVI
                     QIKNLVKNSVDDLKLENISVVIKSSSGQDG"
     gene            complement(1007..1384)
                     /gene="sctI"
                     /locus_tag="ACHY1N_004855"
     CDS             complement(1007..1384)
                     /gene="sctI"
                     /locus_tag="ACHY1N_004855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030257 - type III protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0030254 - protein secretion by the type III
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner rod subunit
                     SctI"
                     /protein_id="HFS4047006.1"
                     /translation="MNNINQSENINIHFNKVSQTNFVDDHTPLAPTPSAAGAAQFLDQ
                     LLPKTAGVSSPEQVLIEEIKKRHLATMNTDLSFDALSAGGLSPEDVLTLQKNVLNANV
                     NVDVVSKLASLLSTSVTKLVSMQ"
     gene            complement(1468..1764)
                     /locus_tag="ACHY1N_004856"
     CDS             complement(1468..1764)
                     /locus_tag="ACHY1N_004856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepZ/EspZ family type III secretion system
                     protein"
                     /protein_id="HFS4047007.1"
                     /translation="MDAANLSPSGRVLPLAATINGNNPVDETTGVMQPENGTNRTIRI
                     LGGVLISAGALAAIGAGIASLCVEDPSQKLGLGIAAGVLGGVTTLGSGLAMKYA"
     gene            1948..2301
                     /gene="cesL"
                     /locus_tag="ACHY1N_004857"
     CDS             1948..2301
                     /gene="cesL"
                     /locus_tag="ACHY1N_004857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE chaperone CesL"
                     /protein_id="HFS4047008.1"
                     /translation="MNLLIKRNVEEFLRLLGNDFYLFDNRVEIDFNGFSFFIEIIDSN
                     VFITFALEYNENAFFSFFNALAPERTQGVIEHIFVYDNKLCLSCLLTNIDVFSLMNTF
                     QQHVQIIERVRRMTS"
     gene            2298..4325
                     /gene="escV"
                     /locus_tag="ACHY1N_004858"
     CDS             2298..4325
                     /gene="escV"
                     /locus_tag="ACHY1N_004858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE export apparatus
                     protein EscV"
                     /protein_id="HFS4047009.1"
                     /translation="MNKLLNIFKKAESYHDLILALFFFMAVMMMIIPLPTVVVDIIIA
                     INISTALLLLMLSIYIKNPLELTSFPTILLITTLMRLSLSVSTTRLILLHHDAGDIIY
                     SFGNFVVGGNIVVGLVIFTIITIVQFMVITKGAERVAEVSARFSLDGMPGKQMSIDGD
                     MRAGVIDPLEAKVLRSRVQKESQFYGSMDGAMKFVKGDAIAGIIIVLVNLFGGVLIGM
                     WQFDMPFSEALSLFSVLSVGDALVAQIPALIISVTAGVVVTRVPGESEKEENLAGDIV
                     QQVSVNSRPFLISAALMIVMAIIPGFPTLVFLFLAVCLLGIAWKLQKKKTFGTGNNKD
                     AMGADLSNSQNISPGAEPLILNLSSNIYSSDITQQIEVMRWNFFEESGIPLPKIIVNP
                     VKNNDSAIEFLLYQESIYKDTLTDDTVYFEAGHAEISFEFVQEKLSANSIVYKTNEAN
                     QQLAHVSGMDVYAKTNDKITFLLKKLVLSNAKEFIGVQETRYLMDIMERKYNELVKEL
                     QRQLGLSKIVDILQRLVEENISIRDLRTIFETLIFWSTKEKDVVILCEYVRIALRRHI
                     LGRYSVRGTLLNVWLIGSDIENELRESIRQTSSGSYLNISPERSEQIIGFLKNIVNPT
                     GNGVILTALDIRRYVKKMIEGSFPSVPVLSFQEVGNNIELKVLGTVNDFRA"
     gene            4309..5649
                     /gene="escN"
                     /locus_tag="ACHY1N_004859"
     CDS             4309..5649
                     /gene="escN"
                     /locus_tag="ACHY1N_004859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE ATPase EscN"
                     /protein_id="HFS4047010.1"
                     /translation="MISEHDFVLERYPRIQRVLNSTVPTLSLNSSTRYEGKITNIGGT
                     IIKARLPKARIGAFYRIEPSQRLAEVIAIDEDEVFLLPFEHISGMYCGQWLSYQGDEF
                     KIRVGDELLGRLVDGIGRPMGSNITAPYLPFERSLYAEPPDPLLRQVIDQPFTLGVRA
                     IDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALL
                     PQSTLSKCVLVVTTSDRPALERMKAAFTATTIAEFFRDQGKNVLLMMDSVTRYARAAR
                     DVGLASGEPDVRGGFPPSVFSSLPKLLERAGPAPKGSITAIYTVLLESDNVNDPIGDE
                     VRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRAAAECKKLIATYKN
                     IELLIRIGEYTMGQDPEADKAIKNRKAIQSFIQQSTKDISSYEKTIESLFKVVA"
     gene            5709..6029
                     /locus_tag="ACHY1N_004860"
     CDS             5709..6029
                     /locus_tag="ACHY1N_004860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312594.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion protein"
                     /protein_id="HFS4047011.1"
                     /translation="MAKINSQIKEVDGKLDDCEQAIKESIASKQAYCASLVNLDKVSL
                     YKYQIKNNAFDEQKQRLYEKKSSLSKEKRSLLDSQKRTKEDLQHVNKSIEKLSFAIKE
                     HYFD"
     gene            6022..>6323
                     /locus_tag="ACHY1N_004861"
     CDS             6022..>6323
                     /locus_tag="ACHY1N_004861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1106 domain-containing protein"
                     /protein_id="HFS4047012.1"
                     /translation="MTSISLKRNLIEPVSFQPSDDWPQGEESFNDIFNRIKKRTPDTS
                     FIRMASLWKRLFYAPGQRRRYFEQGERSFSIICGKLRGIVLTIKCSNGTIYLSITL"
BASE COUNT         1785 a         1143 c         1359 g         2036 t
ORIGIN      
        1 aatgtgttgg aggcatcgtt gtatctgatg tagatgcttg ctctaactta tcaaattgct
       61 tgtcaagcaa agaggcgagt gtgtgttgca ttattgcttt tgacatgttt gcgcgatgat
      121 tattatcttt attaaacagt tggcaaagat accatttttt attagattga aaaatgccca
      181 tttgtttata ttctttacta acggccagaa tattacagag tctgatgaag gtatctgttg
      241 gaacctggcg aaaatcgcca ttaagctcga tatacagaac ccagtaactt ccaaagtcgt
      301 gtaagaaggc atttttttga tagatatgaa aagtaagatg ctttggtgaa cctttgacat
      361 cttttacaaa atcaagagcc gttagccagt cactatcatt cttaacaatg ccattattat
      421 tgttcataca tattacccgt cctgtcctga ggatgacttg ataacgacac taatattttc
      481 tagtttgaga tcgtctacgc tattcttaac taagtttttt atctgaatga ctgatggtgc
      541 taagttaacc tctggcgagc taatgactaa aacagccgct gaggatggtt ggctctcgtt
      601 attgttaaca tttaatgaaa cgctgcaatc gataacaccg gggattttac ttagtaacct
      661 ttctatatct tgttctttga gatagttgat ttttgcattt tcttgtgatg gcgatgccac
      721 tagctgactg ggcggaaaaa taacttcaat atctgcaaat ttctttttcg ggaagccatt
      781 gttatttaaa atggttatcg cacggacaaa atcctctttt tccacactta ttgttacatt
      841 tccacttttg tccatttctt tagatacatt gacatcattg gataacaaca atgcttgcat
      901 ctgattggct tctttttccg ttaatcctgt atacaattgc tctttacatg caactgtcaa
      961 acaaataaaa acaaataaaa aggtgttttt aatgtatttt ctcattttat tgcattgaaa
     1021 ccagttttgt aaccgatgtt gaaagaagac ttgctaactt ggatacgaca tcaacattga
     1081 cgtttgcgtt gagcacattc ttttgtaatg tgagcacatc ttctggcgag agtccacctg
     1141 cagatagggc atcgaaactg agatcggtgt tcattgttgc aagatgtctc tttttaattt
     1201 cttcaattaa aacttgctct ggagaagata caccagctgt tttaggaagt aattgatcaa
     1261 gaaactgagc cgctccagct gcagagggcg ttggtgctaa cggggtatgg tcatcaacga
     1321 aatttgtttg ggatacttta ttaaaatgaa tattaatatt ttctgattga ttaatattgt
     1381 tcatatttac ggttagtctc ttttcatgag agaggtaatg gcataatgca tccatgacct
     1441 ctctatttta tttatgcgat gcgatgatta ggcatatttc atcgctaatc cgctgccaag
     1501 agttgttacg ccacctaata caccggccgc gattcctaag cctaattttt gtgaaggatc
     1561 ttcaacacac agtgatgcga taccagcacc gatagcggct agagcacctg cacttatcaa
     1621 aactccacct aggattctaa tggtacgatt tgttccattt tctggttgca ttactcctgt
     1681 cgtctcatcc actggattat ttccattgat tgtggctgcc agtggtaata ctctgccaga
     1741 agggcttaaa tttgctgcat ccattaactt ttctccattg tctaatttag acatttgtct
     1801 ggttatcaat aaccaaatta tcccatgggc aactattata ttatttaaat agttgcaatg
     1861 tacataaagt acatatactg tatatattat ccaacacgct ttttcaagca ataatatcca
     1921 cacatatact tacttcagag cctgcatatg aatcttttaa ttaaaagaaa cgtagaagag
     1981 tttttaaggt tattagggaa tgatttttat ttgtttgata atcgcgtgga aattgatttt
     2041 aatggttttt ctttttttat tgaaataatt gatagtaatg tgtttattac gtttgcctta
     2101 gagtataacg aaaatgcgtt tttttctttt ttcaatgccc ttgcccctga acggacgcag
     2161 ggagtgattg aacatatttt tgtctacgat aacaaattgt gcttaagttg tttgttaacc
     2221 aatattgatg tgttttctct aatgaatact tttcagcagc atgtgcagat tattgaacga
     2281 gttcgcagga tgacatcatg aataaactct taaatatatt taaaaaagca gagtcatatc
     2341 acgatcttat tctggctctc ttcttcttta tggctgtaat gatgatgatt attccattgc
     2401 caacagttgt ggtggatatc attatcgcga ttaatatatc gacagcattg cttttattaa
     2461 tgctctcaat ctatataaaa aatcctcttg agctaacttc ttttcctaca atcctgttga
     2521 ttacgacgtt gatgcgcctg tcgctcagtg ttagtacaac cagacttatt ctgctgcatc
     2581 acgatgcggg tgacattatt tactccttcg gtaactttgt tgttggcggt aatattgttg
     2641 ttggcctggt catttttacc attatcacca ttgtacaatt tatggttatt acaaaagggg
     2701 ctgagcgtgt tgctgaagtg agtgctcgtt tttctcttga tggtatgcca ggaaaacaaa
     2761 tgagtattga tggtgatatg cgtgcaggcg ttattgaccc gcttgaggca aaagttcttc
     2821 gctcccgagt gcaaaaggaa agccagtttt atggttcaat ggacggggcg atgaagtttg
     2881 taaaagggga cgctattgcc ggtatcatca ttgttttagt taacctgttt ggtggcgtgc
     2941 tcattggaat gtggcaattt gacatgccat ttagtgaagc acttagcctg ttttctgtat
     3001 tgtctgtcgg tgatgctttg gttgcccaga tccctgcgct tattatttcc gtcactgcgg
     3061 gggttgttgt tactcgtgtt cccggtgaaa gcgaaaaaga agaaaacctt gcaggtgata
     3121 ttgttcaaca ggtttctgtt aatagtcgcc cttttttaat cagtgccgca ctcatgatcg
     3181 taatggcgat tattcctggc tttcctacat tggtcttctt gtttctggcg gtttgcctgt
     3241 tgggtatcgc ctggaaatta caaaagaaaa agacgtttgg aaccggaaat aataaggacg
     3301 ctatgggagc tgatttgtct aatagtcaaa atatctcacc gggtgccgag ccgttgattt
     3361 taaacttaag tagtaatatt tatagctcag atattacaca gcagattgag gttatgcgtt
     3421 ggaatttctt tgaggaaagt ggaattccat tgcctaagat tattgttaat ccagttaaaa
     3481 acaatgatag cgctatagaa tttttgctct atcaagagtc aatatacaaa gatactctga
     3541 cagatgatac tgtttatttt gaggctgggc atgcagagat atcatttgaa tttgtccagg
     3601 aaaagctttc ggctaactct atcgtgtata aaacgaatga ggctaaccaa caactagctc
     3661 acgtctcagg tatggatgtt tatgcaaaaa caaatgataa gataacgttt ttgctaaaga
     3721 aacttgtatt gtctaatgcc aaagagttca tcggcgtaca agaaacgcgt tatctgatgg
     3781 acatcatgga gaggaaatat aacgaacttg tgaaagagct tcagcgtcag cttggtctga
     3841 gcaagattgt ggatattctt cagcgtctcg tagaggaaaa tatctcaatt agagatctac
     3901 gaactatttt tgaaacgctt attttttggt ccacaaaaga aaaagatgtg gttatcttgt
     3961 gcgaatacgt tcgtatcgcc ctacgtcggc atattttagg tcgctatagc gttcgcggta
     4021 cacttctgaa tgtttggctt attggctctg atattgaaaa tgagctacga gagtcgatca
     4081 gacaaacgtc atcaggttcg tatttgaata tctcaccgga gcgaagtgag cagattattg
     4141 gcttcttaaa aaatattgtg aatccaacgg ggaacggcgt cattctgacc gctttagata
     4201 tcaggcgcta cgtgaagaaa atgattgaag gttcgttccc gtcagtcccc gtgctctctt
     4261 ttcaggaagt tgggaataat atcgaactta aagtattagg aacggtaaat gatttcagag
     4321 catgattttg tattggaaag atacccacgt atccagagag tgctcaatag cactgtgccg
     4381 acattatcat taaattcgtc taccagatat gaaggcaaga ttaccaatat cggcgggacg
     4441 attatcaagg cgcgtttacc aaaagcgcgt attggcgcct tttacaggat agaacccagt
     4501 caacgtttag ctgaggtgat cgctattgat gaagatgagg ttttcctgct gccttttgag
     4561 catatttccg gcatgtattg tggccagtgg ctaagttatc agggggatga gttcaagatt
     4621 cgtgttgggg acgaactcct tgggcgactg gttgatggta taggcagacc aatggggagc
     4681 aatattactg caccttatct tccgtttgaa cgcagtttgt atgctgaacc ccccgatcct
     4741 ttattaaggc aggttattga tcagccattt acgcttggcg tcagggcaat agatggttta
     4801 cttacttgcg gtattgggca acgtatcggt attttcgcgg ggtccggcgt tggtaaaagt
     4861 acgcttttgg gaatgatttg taatggcgca tccgcggata ttattgtcct tgcccttatc
     4921 ggcgagcgtg gtcgcgaagt aaatgaattc ctcgcgcttt tacctcaatc cacgctttct
     4981 aaatgtgtac tggtcgtcac aacgtcagac cgtcccgcgc tggaaagaat gaaggccgca
     5041 tttacggcga caaccattgc agagttcttc cgggatcagg gcaaaaatgt attattaatg
     5101 atggattccg taactcgtta tgcccgagcc gcgcgtgatg ttgggcttgc atcgggagag
     5161 cctgatgtaa gggggggatt ccctccgagt gttttttcct cgttacccaa attattagag
     5221 cgtgcggggc ctgcgccaaa aggctcaata accgcgattt atacggtgtt gttagaaagc
     5281 gataatgtta atgatcccat tggtgatgaa gtccgctcta ttcttgatgg gcacattgtg
     5341 cttacccgag aacttgcaga ggaaaatcat tttcctgcaa ttgatattgg tttaagcgcc
     5401 agtcgtgtta tgcataatgt tgttacatcg gagcatttgc gtgcggcggc agaatgcaaa
     5461 aagcttatcg caacctataa aaatattgag ctgcttattc gtattggtga gtacacgatg
     5521 gggcaagatc ctgaagcgga taaggcaata aaaaacagga aagcaattca gagctttata
     5581 caacaaagca ccaaagatat cagtagttac gaaaaaacga ttgaaagcct attcaaagtg
     5641 gttgcctgaa tatgttggac agaattttat ctattcgtaa aagcagagcg aatcgattga
     5701 gagaatcaat ggctaagatt aactctcaga taaaagaggt ggatggtaaa ctcgatgact
     5761 gcgagcaagc cattaaagag tcgattgcct ctaagcaggc gtattgtgca tcgctggtga
     5821 atctggataa agtgtcgttg tataaatacc agattaaaaa caatgcattt gatgagcaaa
     5881 agcagcgatt atatgagaaa aaatcctcac tttctaaaga aaagcgttca ttgctcgatt
     5941 cacaaaaacg aacaaaagag gatctacaac atgttaataa atcaatagag aagttatctt
     6001 ttgccataaa ggaacattac tttgactagc atttctctaa aaagaaattt gatagagcct
     6061 gtttcttttc agccgtcaga tgattggccg cagggagaag aaagttttaa tgatattttt
     6121 aatcgcataa aaaaaagaac acctgacact tcgttcatac gaatggcttc tttatggaaa
     6181 cgattgttct acgctcctgg acagaggcga cgctactttg aacaaggaga gcgttcattt
     6241 agtattattt gtggaaagtt acgcggaatt gttttaacaa taaaatgtag taatggaacc
     6301 atttatctgt ctattacact gaa
//
LOCUS       DAZUDJ010000148         6201 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.150, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000148 DAZUDJ010000000
VERSION     DAZUDJ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6201
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.150"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(147..491)
                     /locus_tag="ACHY1N_004862"
     CDS             complement(147..491)
                     /locus_tag="ACHY1N_004862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047013.1"
                     /translation="MSDLAMKVLKWQSTGDVGISSATLASIACGLKKNIYGHHFGAPH
                     DAADFRRCVALVEQIPEIRDSFNKVAKRVPAFKGILNEWDSLVALLKSEMKIHGNKAP
                     ETYRRISELRKD"
     gene            complement(520..687)
                     /locus_tag="ACHY1N_004863"
     CDS             complement(520..687)
                     /locus_tag="ACHY1N_004863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047014.1"
                     /translation="MHFRVTGELNGEPFNRVIEAEDINDCYDHWMIWAQIAHADVTNI
                     RIEELKEHQAA"
     gene            complement(723..1022)
                     /locus_tag="ACHY1N_004864"
     CDS             complement(723..1022)
                     /locus_tag="ACHY1N_004864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309189.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047015.1"
                     /translation="MACSTFNPLTLQKYQPDPEDLCSLCGGNHGKAAMIECKDKIHIC
                     LNCVDVLVDIKNEREDKKRSEAIRALDSWMRDGYSAAQIYDLAISKGEIPGVRIE"
     gene            complement(1180..1458)
                     /locus_tag="ACHY1N_004865"
     CDS             complement(1180..1458)
                     /locus_tag="ACHY1N_004865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016063072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4752 family protein"
                     /protein_id="HFS4047016.1"
                     /translation="MDSFAKYTIIDWIAFLQVLLIWFYMAYRSGQWIVSVACSKGWRW
                     WNRKNKKALALDSFYEAFNLNSLQPGYVIVVTTQSGMTIQIHKPKEEK"
     gene            complement(1458..2141)
                     /locus_tag="ACHY1N_004866"
     CDS             complement(1458..2141)
                     /locus_tag="ACHY1N_004866"
                     /inference="COORDINATES: protein motif:HMM:NF016342.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dATP/dGTP pyrophosphohydrolase domain-containing
                     protein"
                     /protein_id="HFS4047017.1"
                     /translation="MASLERELIRHEHAKWSDSTFGCVGPIGPLKHLSKEALEAAAEP
                     DDLSEWADMHFLLWDAQRRAGISDAEITAAMEDKLKINMERQWPEPKDGEPRLHIKEP
                     GNSPVIPDGLSTVCAEAYQVVGVMADALGVFGDAAVQKVLDNLSQQKLVHRDVLPFSL
                     PVTPDGWISCSELMPDKLIPVMVMYEDGEMWSAMWNGNRWDDGTEYPDPHSVTHWREM
                     PAAPQQEVK"
     gene            complement(2115..2240)
                     /locus_tag="ACHY1N_004867"
                     /pseudo
     CDS             complement(2115..2240)
                     /locus_tag="ACHY1N_004867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309978.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF550 domain-containing protein"
     gene            complement(2251..3006)
                     /locus_tag="ACHY1N_004868"
     CDS             complement(2251..3006)
                     /locus_tag="ACHY1N_004868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047018.1"
                     /translation="MIHYHGGPITPDTCAMRAWKGRHAFISFAHSGQINLAAEYCQSF
                     ALDNGAFTAWKAAGKNKIDWSDYYEFVARWKNHPGFDFAIIPDVIDGGEEENDALLNE
                     WPHGKLAGVPVWHVNESDERFIHLCNEFPRVAIGSCGDYDVKRPTLAVARMKDLIRHI
                     VDGHGQPVTKLHGLRMLNPLIFTKLPLASADSTNVARNIGIDKAWSGAYAPASKETRA
                     ALMVERIEAHNSPGSLAYCEQRDRFEMQLQLAL"
     gene            complement(3008..3415)
                     /locus_tag="ACHY1N_004869"
     CDS             complement(3008..3415)
                     /locus_tag="ACHY1N_004869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ead/Ea22-like family protein"
                     /protein_id="HFS4047019.1"
                     /translation="MSEINSQALREAAEKAGEDKWQAKKINGDFFVIRHGSYTRQHGY
                     TSYQPIAEIDCKPVRDFVAKANPATVLELLDELEAAKKRIAELEAREILLPERSSMLH
                     RTDFHDDYQTVMAYKVSEVIDAIRATGIRIKGE"
     gene            complement(3412..3633)
                     /locus_tag="ACHY1N_004870"
     CDS             complement(3412..3633)
                     /locus_tag="ACHY1N_004870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HFS4047020.1"
                     /translation="MADIIDSASEIEELQRNTAIKMRRLNYQTISATHCCECGDPIDE
                     RRRLVVQGCRTCASCQEDLELISKQRGSK"
     gene            complement(3732..3947)
                     /locus_tag="ACHY1N_004871"
     CDS             complement(3732..3947)
                     /locus_tag="ACHY1N_004871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFS4047021.1"
                     /translation="MTPQQENALRSIARLANSEIKKARQQFPDKNVDDICRSVLKKHR
                     ETVTLMGFTPTHLSLAIGMLNGVFKER"
     gene            complement(4024..4215)
                     /locus_tag="ACHY1N_004872"
     CDS             complement(4024..4215)
                     /locus_tag="ACHY1N_004872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1382 family protein"
                     /protein_id="HFS4047022.1"
                     /translation="MHKASPVELRTSIEMAHSLAQIGVRFVPIPVETDEEFHTLAASL
                     SQKLEMMVAKAEADERDQV"
     gene            complement(4188..4370)
                     /locus_tag="ACHY1N_004873"
     CDS             complement(4188..4370)
                     /locus_tag="ACHY1N_004873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1317 domain-containing protein"
                     /protein_id="HFS4047023.1"
                     /translation="MKHPHDNIRVGTITFVYSVTKRGWVFPGLSVIQNPLKAQRLAEE
                     INNKRGAVCTKHLLLS"
     gene            complement(4367..5047)
                     /locus_tag="ACHY1N_004874"
     CDS             complement(4367..5047)
                     /locus_tag="ACHY1N_004874"
                     /EC_number="3.1.11.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lambda exonuclease family protein"
                     /protein_id="HFS4047024.1"
                     /translation="MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKP
                     RSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARVLFEFTSGVNVTE
                     SPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYLAQVQY
                     SMWVTRKDAWYFANYDPRMKREGLHYVVVERDEKYMAGFDEMVPEFIEKMDEALAEIG
                     FVFGEQWR"
     gene            complement(5044..5829)
                     /gene="bet"
                     /locus_tag="ACHY1N_004875"
     CDS             complement(5044..5829)
                     /gene="bet"
                     /locus_tag="ACHY1N_004875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HFS4047025.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQF
                     IALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNE
                     SCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCA
                     RLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDD
                     DLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA"
     gene            complement(5835..6131)
                     /locus_tag="ACHY1N_004876"
     CDS             complement(5835..6131)
                     /locus_tag="ACHY1N_004876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0060703 - deoxyribonuclease inhibitor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor Gam family protein"
                     /protein_id="HFS4047026.1"
                     /translation="MNAYYIQDRLEAQSWARHYQQIAREEKEAELADDMEKGLPQHLF
                     ESLCIGHLQRHGASKKAITRAFDDDVEFQERMAEHIRYMVETIAHHQVDIDSEV"
BASE COUNT         1466 a         1600 c         1397 g         1738 t
ORIGIN      
        1 gcgttccact cctgaagtgt caagtacatc gcaaagtctc cgcaattaca cgcaagaaaa
       61 agccgcattg atgcggcgat ggtaggtctg gatatcattg agcaatgaac aggcctcacc
      121 gagtgtgagg cggtgttatt tcatggttag tccttgcgta gctcgctgat tcttctgtaa
      181 gtctctggtg ctttgtttcc gtgtatcttc atttcagact tcaacagagc aacgagggaa
      241 tcccattcgt tgaggattcc tttgaatgcc ggaacgcgct ttgcaacctt gttgaatgaa
      301 tctctgattt ctggaatctg ctcaacaagt gcaacgcatc gtctgaaatc ggctgcgtca
      361 tggggagcgc cgaagtgatg accatagata ttctttttca gtccacatgc gattgaggca
      421 agagttgcgc tactgatgcc aacatcgcca gtcgattgcc atttcaaaac cttcatagcc
      481 aaatctgaca tttcttgtct ccaataaaaa aaaccgccat caggcggctt ggtgttcttt
      541 cagttcttca attcgaatat tggttacgtc tgcatgtgct atctgcgccc atatcatcca
      601 gtggtcatag cagtcgttga tgtcctctgc ttcgataact ctgttgaatg gttctccatt
      661 caattcacct gtgactcgga agtgcatttg tgatttcccc aaaagatgct tgagtgcgct
      721 tcttattcga ttcgcacacc tggtatttcg ccttttgaaa tggctaagtc ataaatttgc
      781 gcagcactat acccatctcg catccatgaa tctaaggcgc gaatagcctc gctacgcttt
      841 ttatcttctc tttcattttt gatatcaacg aggacatcaa cgcaattaag gcatatgtgg
      901 attttgtcct tacattcgat catggcagct ttaccatgat ttccgccaca cagtgagcat
      961 aaatcttcag ggtctggctg gtatttctgt aacgttaaag ggttgaatgt tgaacaggcc
     1021 ataatcatct ccataaaaca aaactcgccg tagcgagttc agataaaaga aatccccgtc
     1081 agtgcgagga ttgttattgt cttttcttcg tgcatttgtc gcactttcgg caccatccag
     1141 ataggcacat ccgtccgcaa ttaacacata taggccacat catttttcct cttttggttt
     1201 atgaatctga atggtcatgc cgctttgagt ggtgactaca atgacataac caggctgaag
     1261 actgttaaga ttgaatgctt cgtaaaacga atccaaggcc agcgcttttt tattctttcg
     1321 gttccaccaa cgccatccct tgctacaggc tacactgaca atccactgcc cactcctgta
     1381 agccatataa aaccagatga gcaaaacctg aaggaatgct atccagtcaa taatcgtata
     1441 tttcgcgaag gagtccatca cttcacctcc tgctgcggtg ctgctggcat ttcacgccag
     1501 tgcgtaactg agtgcggatc cggatattcg gtgccatcat cccagcgatt gccattccac
     1561 attgcagacc acatctcacc gtcttcatac atgaccatta ccggaattaa cttatccggc
     1621 attagctcac tacagcttat ccaaccatcc ggagttaccg gaagcgagaa cggcagcaca
     1681 tctctgtgaa caagtttttg ctgtgacagg ttatccagaa ctttctgtac tgctgcatca
     1741 ccgaatacac caagcgcatc tgccataact cctacaacct gataagcctc agcgcatacc
     1801 gtggataaac catccggaat taccggagag ttgccgggtt ctttaatgtg caagcgaggc
     1861 tcaccatctt ttggttcagg ccactggcgc tccatgttga tcttcaattt atcttccata
     1921 gcagcggtaa tttcagcatc gctgatgcca gcacggcgct gtgcatccca caacaggaaa
     1981 tgcatatcag cccactcgct gagatcgtct ggttcggctg cggcttccag agcctctttt
     2041 gagaggtgtt tcagtggacc aatggggcca acgcagccaa atgtggagtc agaccatttg
     2101 gcatgctcgt ggcgaatcag ttcgcgttcc agtgatgcca gtgcaattcg tgccagttcc
     2161 atttgttcgc cacgagtaag cccgttttca agcggatttt taatgaacaa ttcaatacgt
     2221 tctttggtaa tagtggtcat ttgttagtcc ttaaagtgct agttgcaatt gcatttcaaa
     2281 gcggtcgcgt tgttcacaat acgcaagaga accagggcta ttgtgtgcct caatccgttc
     2341 taccattaat gctgcgcgtg tctctttact tgcaggtgca taagccccag accaggcttt
     2401 atcaataccg atgtttcgag cgacgttcgt actatctgcg ctggctaagg gtaattttgt
     2461 gaatatcagc ggatttaaca tgcgcaatcc atgtagtttc gtaaccggct gaccatgccc
     2521 atcaacaatg tgacgaatca ggtctttcat tctggctacc gcaagagttg ggcgctttac
     2581 gtcatagtcg ccacaactac cgatagccac tcgcggaaac tcattgcaca aatgaataaa
     2641 tcgctcgtca ctttcattca cgtgccacac tggaacgcca gctagttttc cgtgaggcca
     2701 ctcattcaga agcgcatcat tttcctcctc tccgccatca ataacatccg ggataatggc
     2761 aaaatcgaat cctgggtgat tcttccagcg agcaacaaac tcgtagtaat cgctccagtc
     2821 gattttgttt ttgccagctg ctttccaggc ggtgaatgca ccgttgtcca gcgcgaacga
     2881 ctgacagtat tcagccgcga gattgatctg gcctgaatgc gcaaaactga taaacgcatg
     2941 tcgccctttc catgctctca ttgcgcacgt atcaggagta ataggcccac cgtggtagtg
     3001 aatcatctca ctctcctttg atgcgaatgc cagtagcgcg gattgcatcg atgacttcag
     3061 aaactttgta tgccattacc gtttggtaat catcgtgaaa atctgttcga tgaagcatgc
     3121 tgctacgttc cgggagcagt atttcccgcg cttccagttc tgcaatgcgc ttttttgctg
     3181 cttccagttc atccagtaat tccagcacgg tagccggatt agccttggca acaaaatccc
     3241 ggactggctt acaatcaatc tccgcaatgg gttgatacga tgtgtagcca tgctgtcttg
     3301 tataactacc gtgacgaata acgaaaaaat caccatttat ttttttagcc tgccacttat
     3361 cttcaccggc tttctctgcc gcttcacgca gtgcctgaga gttaatttcg ctcacttcga
     3421 acctctctgt ttactgataa gctccagatc ctcctggcaa cttgcacaag tccgacaacc
     3481 ctgaacgacc aggcgtcttc gttcatctat gggatcgcca cactcacaac aatgagtggc
     3541 ggatatagtc tggtagttca gacgacgcat ttttattgct gtattgcgct gtaattcttc
     3601 aatttctgat gctgaatcaa tgatgtccgc catctttcat taatccctga attgttggtt
     3661 aatacgcttg agggtaaatg cgaataataa aaaaggagcc tgtagctccc tgatgatttt
     3721 gcttttcatg ttcaccgttc cttaaagacg ccgtttaaca taccgattgc cagacttaag
     3781 tgagtcggtg tgaatcccat cagcgttacc gtttcgcggt gcttcttcag tacgctacgg
     3841 caaatgtcat cgacgttttt atccggaaac tgctgtctgg cttttttgat ttcagagtta
     3901 gccagacggg caatgctgcg aagggcgttt tcttgctgag gtgtcattga acaagtccca
     3961 tgtcggcaag cataagcaca cagaatataa agcccgctgc cagaagaatg cattcagtgg
     4021 ttgtcatacc tggtctctct catctgcttc tgctttcgcc accatcattt ccagcttttg
     4081 tgaaagggat gcggctaacg tatgaaattc ttcgtctgtt tctactggta ttggcacaaa
     4141 cctgactcca atttgagcaa ggctatgtgc catctcaatg ctcgttctta actcaacagg
     4201 agatgctttg tgcatacagc ccctcgttta ttatttatct cctcagccag ccgctgggct
     4261 ttcagtggat tttggataac agaaaggccg ggaaataccc agcctcgctt tgtaacggag
     4321 tagacgaaag tgatcgtgcc tacgcggata ttatcgtgag gatgcttcat cgccattgct
     4381 ccccaaatac aaaaccaatt tcagccagtg cctcgtccat tttttcgatg aactccggca
     4441 ccatctcgtc aaaacccgcc atgtactttt catcccgctc aaccacgaca taatgcagtc
     4501 cttcacgctt catacgcggg tcatagttgg caaagtacca ggcatctttt cgcgtcaccc
     4561 acatgctgta ctgcacctgg gccaggtaag ccgattttat ggcctcgaaa ccaccgagcc
     4621 ggaatttcat gaaatcccgg gaggtaaacg ggcatttcag ttcaaggccg ttgccgtcac
     4681 tgcataaacc atcgggagag caggctgtac gcatactttc gtcgcgatag ataatcgggg
     4741 attcagtaac attcacgccg gaggtgaact caaacaggac tctggcgtcg ttctcgtatt
     4801 gttttcccca ggccagtgct ttggcattaa cttccggagc cacaccggtg caaacctcag
     4861 caagcagggt gtggaagtag gacattttca tgtcaggcca cttttttccg gagcggggtt
     4921 ttgctattac gttatgaact tctgaagctg tgatgacgcc gagccgtaat ttgtgccacg
     4981 catcatcccc ctgttcgaca gctctcacgt cgatcccggt acgctgcagg ataatgtccg
     5041 gtgtcatgct gccaccttct gctcagtggc tttctgtttc aggaatccaa gagctttcac
     5101 tgcttcggcc tgtgtcagtt ctgacgatgc gcgaatgtcg cggcgaaata tctgggaaca
     5161 gagcggcaat aagtcgtcat cccatgtttt atccagggcg attagcagag tgttaatctc
     5221 ctgcatggtt tcatcgttaa ccggagtgat gtcgcgttcc ggctggcgtt ctgcagtgta
     5281 tgcagtattt tcgacaatgc gctcggcttc atccttgtca tagataccag caaatccgaa
     5341 ggccagacgg gcacactgaa tcatagcttt atgccgtaac atccgtttag gatgcgactg
     5401 ccacggcccc gtgatttctc tgccttcgcg ggttttgaat ggttcgcggc ggcattcatc
     5461 catccattcg gtaacgcaga tcggatgatt acggtccttg cggtaaatcc ggcatgtaca
     5521 ggattcattg tcctgctcaa agtccatgcc atcaaactgc tggttttcat tgatgatgcg
     5581 ggaccagcca tcaacgccca ccaccggaac gatgccgttc tgcttatcag ggaaggcgta
     5641 aatttctttc gtccacggat taaggccgta ctggttggcg acgatcaaca atgcgatgaa
     5701 ctgcgcatcg ctggcatcgc ctttaaatgc cgtctggcga agagtggtga tcagttcctg
     5761 tgggtcgaca gaatccatgc cgacacgttc agccagcttc cctgccagcg ttgcgagtgc
     5821 tgtactcatc cgttttatac ctctgaatca atatcaacct gatggtgagc aatggtttca
     5881 accatgtacc ggatgtgttc tgccatgcgc tcctgaaact caacatcgtc atcaaacgca
     5941 cgggtaatgg cttttttgct ggccccgtgg cgttgcaaat gaccgatgca tagcgattca
     6001 aacaggtgct ggggcaggcc tttttccatg tcgtctgcca gttctgcctc tttctcttca
     6061 cgggctatct gctggtagtg acgcgcccag ctctgagcct caagacgatc ctgaatgtaa
     6121 taagcgttca tggccgaact cctgaaatag ctgtgaaaat atcgcccgcg aaatgccggg
     6181 ctgattagga aaacaggaaa g
//
LOCUS       DAZUDJ010000149         6094 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.151, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000149 DAZUDJ010000000
VERSION     DAZUDJ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6094
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.151"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..280
                     /locus_tag="ACHY1N_004877"
     CDS             <1..280
                     /locus_tag="ACHY1N_004877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047027.1"
                     /translation="KDKRTPCGNYFFRLDKLDCVSLADNSGLTPLIEVTGGYVEPSVT
                     YEQFMSFLFQVFDDVSNGDNSIRIYELMVDEETVRDVPPRTRKTITPQ"
     gene            complement(285..764)
                     /locus_tag="ACHY1N_004878"
     CDS             complement(285..764)
                     /locus_tag="ACHY1N_004878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047028.1"
                     /translation="MKFNVFFKKDHGSHWVLSDGSPLFESPLFETRPKAIDDLENFVG
                     LMESPIFIKAGDDINSGDTENCPSVVISLKQHESLWGWELFISKNGQLSKVTESSGNG
                     FDSLELAKQSAQFFINAIIDAPILDQADVAIPGMHFSKSFEETHHIGDIHPSSKWFK"
     gene            903..1124
                     /locus_tag="ACHY1N_004879"
     CDS             903..1124
                     /locus_tag="ACHY1N_004879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001656632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage filamentation protein Fil family protein"
                     /protein_id="HFS4047029.1"
                     /translation="MDLTQCPSLASLLTHGQQITHRQHQRGWIETPDGRFFQPKAADV
                     QFVKNCRVPFMSRPRNKRRWFSRLMGIFA"
     gene            1146..1529
                     /locus_tag="ACHY1N_004880"
     CDS             1146..1529
                     /locus_tag="ACHY1N_004880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001358517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047030.1"
                     /translation="MDKTGQQPGRRQFLEQRARLQASLNVSRVNDTATRFNRLDDACK
                     KVIFILANDASRYIAGMPKLTAKQLGCTYENLTEKEQTCLLMGIKRLSEFAASMPWEF
                     EDYAAPRAEIQAIRDKPPAPDNAVN"
     gene            1600..2490
                     /locus_tag="ACHY1N_004881"
     CDS             1600..2490
                     /locus_tag="ACHY1N_004881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HFS4047031.1"
                     /translation="MIRSLVKWPGGKGRVMPDLLPILPKADCLVEPFVGGASVFLNTE
                     YRRYILGDINPDLINLYRQITRWPDAVIDAARPLFKVYGDKDGYKWIRDDFNARARDL
                     LSLRSVFEDGPDAGKILRAAQFLYLNRHGYNGVVRYNQQGGYNVPFGRHKTPPYFPEE
                     QIRLFSEKANDTKAIFVCCDFQSTLKIMIGSDAVIYCDPPYLPTSETANFTQYHTAPF
                     GIKEHRQLAAALLDINRLTGSPVILSNSDTPATCEIYRSFNFQEISVNRSVSANAITR
                     GAASEVIGILKVATSTGICE"
     gene            2487..5099
                     /locus_tag="ACHY1N_004882"
     CDS             2487..5099
                     /locus_tag="ACHY1N_004882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HFS4047032.1"
                     /translation="MTNAFAWPWNAPRPAVGPYIYEPKKIAPLAGAVAHHPAVKKHID
                     HIFKRAGYNPAEVRDRDALIQALDRYEPCGLPLAAHQNIIRQEMEAAKATAAAWANTP
                     EGVEARLLSEPFFIREVWRKKIEWLRVNRETRHTNDFLMGTVKKSLLRLDVVRTRQGV
                     SPDITGELAAYWFGRWQRLADFTKREALSAANEIASRMAEMLGTECEALGQNVSDMNV
                     EELDWLYCHLGREMLALRIVPPAWYAPWERDRICTAILRMASPDWWGRKIWRLRCDWR
                     ENQLRAVGAVNKKAHAYVSASSLIEWQEQRRKNRDFFKSHELVDEDGNVSSLEDMINK
                     STSNPAIRRHELMARMAGVELVAQSRGDVGIFLTITCPSKYHSNIASGHHNAKWNHST
                     VAQAQCYLCRVWNRATAKLKREDLRPYGFRVAEPHHDGTPHWHALLFMPQEQVKATVA
                     ILRTYFIAEDRDELGRNTGARFKSKKMDPRKGSATAYIAKYISKNIDGHALAGELDDE
                     SGKPLNESAKYAMAWASLHRIRQFQPIGQPPISVYRELRKLSNQITTRQKIDSTFKRG
                     APLLVDPAMDAVCAAADVGCFATYIIRQGGVLIPRENYVVRLAYQPADEMNAYCEIPE
                     KVFGVWSPRLGDASRICTRLVKWKIRAKSKTVTGAKSGPGLGVDLLPSPTGDAWSSVN
                     NSTEDEKITDFSPGVEGITEESEEEIVDFENMDQPTRRKLIRRLREAPFKRRHSGSPY
                     EPGSELDVAWRSAVEKTEARSVVDKARRAALAPAVASLLADAALCLVEISEIQAVSLL
                     MGSRLEIGGKFYQASAGGQLITRQLPNESRTVNKLWEHLRDNHGIDATHLRFDPVGEY
                     QKMLAGAEGRYPKE"
     gene            5479..>6094
                     /locus_tag="ACHY1N_004883"
     CDS             5479..>6094
                     /locus_tag="ACHY1N_004883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000264504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047033.1"
                     /translation="MERKIIFNNGFLSINREVIIIFLIYFILVGLGISGVIYSRYVDE
                     GVKYLLVTPSFLNNSPLNWTTSVWAGVLGIHGTIAALSITFMGMFVSQVSNYSEHGFE
                     NICKSMLLRKTSFLKFSLNSIFSLLSGIVLLSCGGGMITYAISIFVSLYFIFNYGSMY
                     LKLYNVTENPTIITDRLFFELDKAKNDYLLIDERRRTIENKFLNM"
BASE COUNT         1590 a         1399 c         1527 g         1578 t
ORIGIN      
        1 taaggacaaa agaacgcctt gcggtaatta ctttttccgt ttggataagt tggactgcgt
       61 ttctttagca gataattcag ggctaacacc gttaattgag gttactggtg ggtatgttga
      121 acccagcgtc acttatgagc agttcatgag ttttcttttt caggtatttg atgacgtatc
      181 aaacggtgat aacagcatca gaatttatga gttgatggtt gatgaagaaa ccgtgcgaga
      241 tgttccacct cgcacaagaa aaacgataac gccgcagtga tggattattt gaaccattta
      301 ctggatgggt gaatgtcacc aatgtggtgc gtttcctcga aagattttga gaagtgcata
      361 ccggggatag cgacatcggc ttgatccaga ataggagcgt cgataatggc attaataaaa
      421 aactgggcac tttgctttgc taattctaat gagtcaaagc cattacctga actttcggta
      481 actttagaca gttgtccatt ttttgagata aataactccc agccccatag cgattcatgc
      541 tgttttaaag aaataactac agatggacag ttttctgtat cgccagaatt aatatcgtca
      601 ccagccttaa taaaaattgg cgattccata aggcctacaa agttctcaag gtcatcaatg
      661 gctttaggtc ttgtttcaaa tagtggactt tcaaagaggg gggaaccatc ggaaagtacc
      721 cagtgtgatc cgtggtcttt tttaaaaaac acattgaatt tcattacaac tccttctgtg
      781 ttggtgattg ttatgcctga ttcactgctc aaagttacac aggcatagcg atgttatcac
      841 aggaaacacg tgccgggcgt ggggttatat cccggcatct tttcaatatg acggagatca
      901 acatggactt aacacagtgc ccttcactcg ccagcctgct cacccacggc cagcagatca
      961 cccaccgtca gcatcaacgc ggctggattg aaaccccgga cgggcggttc ttccagccta
     1021 aagcggcaga tgttcaattt gttaaaaact gccgtgtacc gtttatgtcg cgcccgcgta
     1081 ataagcgccg ctggttttcc cgcttaatgg gcatctttgc gtagttcggg gaggtggtta
     1141 tgttgatgga taagacagga caacagccag gccgtcgcca gttcttagag caacgggctc
     1201 gactgcaagc aagtttgaac gtctcacgcg tgaacgacac tgcaacccgt tttaaccgcc
     1261 tggatgatgc ctgtaaaaag gtgattttca tcctggcaaa cgatgcgtcc agatacatag
     1321 ccggaatgcc gaagctgacc gccaaacagc tgggttgtac ttacgaaaat ctaaccgaaa
     1381 aggagcaaac gtgccttttg atgggcatta agcgcctttc cgaatttgca gcatcaatgc
     1441 cgtgggaatt tgaggactac gccgcaccac gcgccgaaat tcaggcgata cgcgacaaac
     1501 cacccgcgcc agataacgca gtaaattaac aactaactac ccacaaaaaa gaaacaggcg
     1561 ctaacgcgtc gggcttcttg caccctggag aaagtaaaaa tgattcgatc tctcgttaaa
     1621 tggcccggtg gtaaaggccg cgttatgcct gatttgctgc cgattctgcc gaaagccgat
     1681 tgcctggtgg aaccgtttgt cggcggtgct tctgttttcc tcaatactga atatcgccgt
     1741 tatatcctgg gtgatatcaa cccagattta attaacctgt atcgccagat aacccgctgg
     1801 cctgatgcgg tgatcgacgc tgctcgccca ctgtttaaag tgtacggcga taaagacggc
     1861 tataagtgga tccgcgatga tttcaacgcc cgcgcccgtg acctactgtc attgcgcagt
     1921 gtgtttgaag atgggccgga cgcgggcaag attcttcgtg cagcacaatt tctttacctg
     1981 aaccgtcacg gatataacgg cgtagtacgc tacaaccaac agggtggata taacgttccc
     2041 tttgggcgtc acaaaacccc gccttacttc ccggaagaac aaatccgttt attctctgaa
     2101 aaagctaacg acacgaaagc tattttcgtg tgctgcgatt tccagagcac gttaaaaatc
     2161 atgattggta gtgacgcggt tatctattgc gatccgccat acctgccaac aagcgaaacc
     2221 gctaatttca cccaatacca caccgccccg tttgggatta aagagcatcg ccagttagct
     2281 gccgctctgc tggatattaa ccgccttact ggttcgccgg tgatcctgtc caatagcgac
     2341 accccagcca cctgcgagat ttatcgctct ttcaacttcc aggaaattag cgttaaccgt
     2401 tctgtcagcg cgaacgccat tacccgaggg gccgccagtg aggtgatcgg tattctcaag
     2461 gttgcgactt ctacgggcat atgtgaatga ctaacgcttt cgcatggcct tggaacgcac
     2521 cgcgtccagc tgttggcccg tacatctatg aaccgaaaaa aatcgccccg cttgctgggg
     2581 cggtggcgca tcatcctgcc gtaaaaaaac atatcgatca catcttcaaa cgtgccggtt
     2641 acaatcccgc cgaagttcgt gaccgtgatg cgctcatcca ggcgctggac aggtacgaac
     2701 catgcggcct gccactggcc gcccatcaaa atataatccg gcaagaaatg gaagccgcta
     2761 aagccacggc ggcagcctgg gccaatacgc cagaaggtgt cgaagcacgt ttattatcag
     2821 agccgttctt cattcgtgaa gtctggcgta aaaaaattga gtggttacgg gtcaaccgtg
     2881 aaaccagaca caccaatgat tttcttatgg ggacagtgaa aaaatcattg ctgcgtcttg
     2941 atgttgtgcg cacaaggcaa ggtgtttcgc ctgatatcac cggcgaactg gccgcgtact
     3001 ggttcgggcg ctggcaacgg ctggctgatt tcacaaagcg ggaagcacta agcgccgcta
     3061 atgagatcgc cagccgcatg gctgaaatgc tggggacgga atgcgaagcc ctgggacaga
     3121 atgtttccga catgaacgtc gaagaactgg actggcttta ttgtcatctg ggccgcgaaa
     3181 tgctggcgct tcgcattgtg ccgcctgcat ggtatgcgcc gtgggaacgt gatcggatat
     3241 gtacggccat tttgcgtatg gcttcgcctg actggtgggg gcgcaaaatc tggcgcctgc
     3301 gttgtgactg gcgcgaaaac cagctgcgag ccgttggcgc ggtaaataaa aaagcgcacg
     3361 catacgttag cgcttccagc ctgatcgagt ggcaggaaca gcgccgtaaa aaccgggatt
     3421 ttttcaaaag tcatgaactg gtagacgaag acggcaacgt ttcctcactt gaggacatga
     3481 ttaataaatc cacgtcaaac ccggctattc gtcgccatga gcttatggcc cgaatggctg
     3541 gggttgagct tgttgcccaa agtcgcggcg atgttggcat cttcctgaca atcacttgcc
     3601 cgtcgaaata tcacagtaat attgcatccg gccaccataa cgccaaatgg aatcattcca
     3661 ccgtcgccca ggcgcagtgc tatttatgcc gtgtgtggaa ccgggcaacc gccaaactga
     3721 aacgcgaaga tttgcgccct tatggcttcc gtgtcgccga gccgcatcac gatgggacac
     3781 cacactggca cgcgttgctg tttatgccac aagagcaagt caaagccacg gttgcgatcc
     3841 ttcgcaccta cttcattgcg gaagaccgcg acgagctggg ccgcaatacc ggcgctcgtt
     3901 tcaagtcaaa aaaaatggac ccacggaaag ggtcagcaac ggcatacatc gctaaataca
     3961 tttcgaagaa tatcgacggc cacgcgctgg ccggtgaact ggacgacgaa agcggcaagc
     4021 cgctgaatga aagcgccaaa tatgcaatgg cctgggcatc gcttcaccgt atccgccagt
     4081 ttcagcccat cggacagccg cccatatcgg tttaccgcga gctgcgcaaa cttagtaatc
     4141 agatcacgac ccgacagaaa attgacagta ccttcaaacg tggtgcgcca ttgcttgtgg
     4201 atcctgcaat ggatgcggtt tgcgccgctg ccgatgtcgg atgctttgct acttacatca
     4261 tccgccaggg tggtgttttg atcccgcgag aaaactatgt cgtccgtctg gcctatcagc
     4321 ccgctgatga aatgaatgct tattgtgaga tccccgaaaa ggttttcggg gtctggtcgc
     4381 cgcgtctggg ggatgcctcc cgtatttgca cccgtctggt taagtggaaa attcgagcca
     4441 aatccaaaac cgtcactggg gccaaaagcg gccccggttt gggggttgac cttttgccgt
     4501 cgccaaccgg cgacgcttgg agttctgtca ataactctac ggaagacgaa aaaatcaccg
     4561 atttttcgcc tggtgtggag ggtattacag aagaatcaga agaggaaatc gtcgattttg
     4621 aaaatatgga ccagccaacg cggcgcaaat tgatacggcg actacgtgaa gcaccattca
     4681 aaaggcggca cagcggatca ccttatgaac cagggagcga attagatgtt gcctggcgtt
     4741 ctgccgtgga aaaaaccgag gccagatcgg tggttgataa agccaggcgg gcagcgcttg
     4801 cccctgcggt tgccagtctg ctggctgatg cggcgttgtg tttggttgag atttcagaga
     4861 ttcaggccgt ttcgctgtta atggggagcc gtctggagat tggcgggaaa ttttatcaag
     4921 ccagtgctgg cggccagttg ataacgcgtc aattacctaa tgagtcacgg acggtgaata
     4981 aattatggga acatttacgg gataaccacg gcattgatgc cacgcacctg cggtttgatc
     5041 cggtcgggga atatcaaaaa atgctggcgg gtgcggaagg tcgctaccct aaagaatgaa
     5101 ttaaatcacg ctatccgtcg cagctggttg cgtcggatag cgtgattctg cgggggcggg
     5161 cggcaaagag cccgcatttg agttctgtca gcgcgatgcc cctaatccaa tatctaaata
     5221 tgcagttacg gcataatgtt aatagcggtc atattcggta tgctccagtt agaaactacg
     5281 ctgcgatgtt aaagatgagt gatacaagtg agtgggctag gctgtttgac tcagcagagt
     5341 aaagaggtaa tcttgtttaa gacaagtttc aagatagaat gattaatgtt atttgaagat
     5401 ttatgtaata caatatcatt gcagagattt ttagataatt aataaatcat gttgtcttat
     5461 taaatgtggg gtctgatttt ggaaagaaaa attattttta ataatggttt tttaagtata
     5521 aatagggaag ttataattat cttcttgatc tactttattc tggtcgggtt gggtatttcc
     5581 ggtgtaatct actctagata tgttgatgaa ggggtaaagt atttacttgt aacaccatct
     5641 tttctcaata attccccatt gaattggact actagtgttt gggcgggagt tttaggcata
     5701 catggaacta ttgctgcact atcaattaca tttatgggaa tgtttgttag tcaggtttct
     5761 aattattctg aacatggctt tgaaaatatt tgtaagtcga tgttgttgcg gaaaactagt
     5821 tttttaaagt ttagtttaaa ttctattttt agtcttttaa gtggtatcgt attgctttca
     5881 tgtggtggcg gcatgattac ttatgctata tccatttttg tatcgttata ctttattttt
     5941 aattatggtt caatgtatct gaaattatat aatgttactg agaatccaac tataataact
     6001 gatcgtttat tttttgagct tgataaggct aaaaatgatt atttattgat tgacgaacgt
     6061 agaagaacta tagaaaataa atttttaaac atga
//
LOCUS       DAZUDJ010000150         5743 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.152, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000150 DAZUDJ010000000
VERSION     DAZUDJ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5743
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.152"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(129..377)
                     /locus_tag="ACHY1N_004884"
     CDS             complement(129..377)
                     /locus_tag="ACHY1N_004884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemagglutinin"
                     /protein_id="HFS4047034.1"
                     /translation="MGAYLGSKVKGEDPTVPMVGNAIGTVLGNKAGEKFTKEMLSKGY
                     SPVTSDVIGTVSGGTMTIGTAIDFGIEESQKKGDSNEK"
     gene            741..935
                     /locus_tag="ACHY1N_004885"
     CDS             741..935
                     /locus_tag="ACHY1N_004885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-zinc-cadmium resistance protein"
                     /protein_id="HFS4047035.1"
                     /translation="MVFVATQHGQKVEFTPQPVKLGQSSGDSQWIEVVNGLNQGQKYA
                     AQGSFLLKSEMEKGEASHEH"
     gene            925..1761
                     /locus_tag="ACHY1N_004886"
     CDS             925..1761
                     /locus_tag="ACHY1N_004886"
                     /inference="COORDINATES: protein motif:HMM:NF013069.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HFS4047036.1"
                     /translation="MSTKSPHIPDHESVKPEGLFDRLIQFSIHNAIWVMLFVAAWIAI
                     GIYSYQKLPIDAVPDITNTQVQINTSANGFTALEMEQRITYPIENAMSGMPKMEQTRS
                     ISRYGLSQVTIIFEDGTDIYWARQLINQRLQEAMGEMPEDVQPNMSPISTGLGEIYQW
                     VIKAEPNAKKPDGTPYSAMDLREIQDWIVRPQLQRVKGVAEINSIGGFNKTYVVAPDL
                     NRLQQLQIPLSDLQTALTENNENRGAGYIEKNGQQLTVRVPHSIVNKTFLSFIFNGLF
                     SC"
     gene            2002..2817
                     /gene="sul2"
                     /locus_tag="ACHY1N_004887"
     CDS             2002..2817
                     /gene="sul2"
                     /locus_tag="ACHY1N_004887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /protein_id="HFS4047037.1"
                     /translation="MNKSLIIFGIVNITSDSFSDGGRYLAPDAAIAQARKLMAEGADV
                     IDLGPASSNPDAAPVSSDTEIARIAPVLDALKADGIPVSLDSYQPATQAYALSRGVAY
                     LNDIRGFPDAAFYPQLAKSSAKLVVMHSVQDGQADRREAPAGDIMDHIAAFFDARIAA
                     LTGAGIKRNRLVLDPGMGFFLGAAPETSLSVLARFDELRLRFDLPVLLSVSRKSFLRA
                     LTGRGPGDVGAATLAAELAAAAGGADFIRTHEPRPLRDGLAVLAALKETARIR"
     gene            2904..3206
                     /locus_tag="ACHY1N_004888"
     CDS             2904..3206
                     /locus_tag="ACHY1N_004888"
                     /inference="COORDINATES: protein motif:HMM:NF014877.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047038.1"
                     /translation="MVRKYFGTDGIRGKANEGAMTAETALRVGMAAGRVFRRGDHRHR
                     VVIGKDTRLSGYMLEPALTAGFTSMGMDVFLFGPLPTTYRKNKRPFHPSPTALDRS"
     gene            complement(3590..4426)
                     /locus_tag="ACHY1N_004889"
     CDS             complement(3590..4426)
                     /locus_tag="ACHY1N_004889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="HFS4047039.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLK
                     PIEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATE
                     IAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMM
                     SNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDP
                     RRIAQMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQT
                     SY"
     gene            complement(4426..5229)
                     /locus_tag="ACHY1N_004890"
                     /note="aph(3'')-Ib"
     CDS             complement(4426..5229)
                     /locus_tag="ACHY1N_004890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3'')-Ib"
                     /protein_id="HFS4047040.1"
                     /translation="MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASR
                     RGELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAW
                     PSMGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLL
                     ARVERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLA
                     LMIANAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
     gene            5515..>5743
                     /locus_tag="ACHY1N_004891"
     CDS             5515..>5743
                     /locus_tag="ACHY1N_004891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HFS4047041.1"
                     /translation="MCELDILHDSLYQFCPELHLKRLNSLTLACHALLDCKTLTLTEL
                     GRNLPTKARTKHNIKRIDRLLGNRHLHKERLA"
BASE COUNT         1422 a         1538 c         1408 g         1375 t
ORIGIN      
        1 aagatatatg actaccggct ttaaagaaac tgaccacttg tccaagaaga atcccagaaa
       61 agctaagtat agatattagc aatatacacc ttgaaaaaag atagaataac agccataagt
      121 caggagattt atttttcatt actatctcct ttcttctgag attcttcaat gccgaagtcg
      181 atagctgtac ctatagtcat agtcccccca gagacagttc caataacatc agaagttact
      241 ggcgagtatc ccttcgatag catttctttg gtgaatttct ctccggcttt gttacccaga
      301 acagtaccta ttgcattccc caccattggc actgtagggt cttcgccttt aactttactt
      361 cctaagtaag ctcccattgt gttaataaat gtgctgaaaa tgacactttt accctgtgta
      421 agcccacctt cacctgcggc aataagagta tccgtagcac tatatttctc acccggctta
      481 agggttaaat actgcttaat gccatctgtt acacctccta aaaggctacc cccaataaca
      541 gcaacggtac ccgcggctgg gactataagt tcgccaccaa gaacagaagc acctgctccc
      601 catgcaatca gtaaacctct gacaggatcc tgtccttccg gaagattacc tgttgcaagt
      661 ttatcagaag catacttaat tgtgaaagta ccgcattacg ggtacttaag tccgcagttc
      721 agaatgtcga tggaaaagat gtggtttttg tcgccactca gcatggacaa aaagttgaat
      781 tcactccgca gccggtgaaa ttaggtcaat cgtctgggga tagccagtgg attgaagtgg
      841 taaatgggct taatcaggga caaaaatatg ccgctcaagg cagtttctta ctgaaatctg
      901 agatggaaaa aggagaggct tcacatgagc actaaaagcc ctcacattcc agaccacgaa
      961 tcggtaaaac ctgaagggct gtttgatcgg ctgatccagt tttctattca taacgcaatc
     1021 tgggtcatgc tgtttgttgc agcctggatt gctattggta tttatagtta tcaaaagtta
     1081 ccgattgatg ctgtaccgga tattaccaat actcaggtgc agattaacac ttcagccaat
     1141 ggctttacgg ctttggaaat ggaacagcgg attacctatc caattgagaa tgccatgtca
     1201 ggcatgccga aaatggaaca aacccgttcg atttcacgct acggcttatc gcaagtgacc
     1261 atcatttttg aagatggcac ggatatttac tgggccagac agcttatcaa ccagcgcttg
     1321 caagaagcaa tgggagaaat gcctgaagat gtgcaaccta acatgtcgcc tatttcgaca
     1381 ggtttaggtg aaatctatca atgggtgatt aaagccgaac caaatgctaa aaagccggat
     1441 ggaacccctt attcggcgat ggatttacgt gaaattcagg attggattgt aagaccgcaa
     1501 ttacagcgcg taaaaggcgt tgcggagatc aacagtatcg gtggctttaa taaaacctat
     1561 gtggttgccc ctgatctgaa ccgattgcaa caattgcaaa ttcctttgtc tgatttacaa
     1621 actgccttaa cagagaataa tgaaaaccgt ggtgctggct atattgagaa aaatggacaa
     1681 cagctaacgg ttcgtgttcc ccactctatt gtaaacaaga catttttatc ttttatattc
     1741 aatggcttat tttcctgcta attggtaata ccatgaaaaa taccatgctc agaaaaggct
     1801 taacaatatt ttgaaaaatt gcctactgag cgctgccgca cagctccata ggccgctttc
     1861 ctggctttgc ttccagatgt atgctattct gctcctgcag ctaatggatc accgcaaaca
     1921 ggttactcgc ctggggattc cctttcgacc cgagcatccg tatgagactc atgctcgatt
     1981 attattatta tagaagcccc catgaataaa tcgctcatca ttttcggcat cgtcaacata
     2041 acctcggaca gtttctccga tggaggccgg tatctggcgc cagacgcagc cattgcgcag
     2101 gcgcgtaagc tgatggccga gggggcagat gtgatcgacc tcggtccggc atccagcaat
     2161 cccgacgccg cgcctgtttc gtccgacaca gaaatcgcgc gtatcgcgcc ggtgctggac
     2221 gcgctcaagg cagatggcat tcccgtctcg ctcgacagtt atcaacccgc gacgcaagcc
     2281 tatgccttgt cgcgtggtgt ggcctatctc aatgatattc gcggttttcc agacgctgcg
     2341 ttctatccgc aattggcgaa atcatctgcc aaactcgtcg ttatgcattc ggtgcaagac
     2401 gggcaggcag atcggcgcga ggcacccgct ggcgacatca tggatcacat tgcggcgttc
     2461 tttgacgcgc gcatcgcggc gctgacgggt gccggtatca aacgcaaccg ccttgtcctt
     2521 gatcccggca tggggttttt tctgggggct gctcccgaaa cctcgctctc ggtgctggcg
     2581 cggttcgatg aattgcggct gcgcttcgat ttgccggtgc ttctgtctgt ttcgcgcaaa
     2641 tcctttctgc gcgcgctcac aggccgtggt ccgggggatg tcggggccgc gacactcgct
     2701 gcagagcttg ccgccgccgc aggtggagct gacttcatcc gcacacacga gccgcgcccc
     2761 ttgcgcgacg ggctggcggt attggcggcg ctgaaagaaa ccgcaagaat tcgttaactg
     2821 cacattcggg atatttctct atattcgcgg ttcagcaggc atgtcccctt tgagggcgac
     2881 ccgacgacag gataatcgac cttatggtgc gcaaatattt cggcacagac ggtattcgtg
     2941 gcaaagccaa cgaaggcgcg atgacggcgg aaaccgcctt gcgcgtcggc atggcggctg
     3001 gccgtgtctt tcgtcgcggt gaccaccgcc atcgtgtcgt gatcggcaag gatacgcgcc
     3061 tgtcgggcta tatgcttgaa cccgcgctca cagccggttt cacctcgatg ggcatggacg
     3121 tattcctttt tggcccgctg ccgacaacgt ataggaagaa taaacgccct tttcacccaa
     3181 gtccaacagc tttggaccgc agttgactct ttcgacaccc ctgcgatgca acccaatccg
     3241 gctgacgggg agccagcaac gctgaaaatt taccctcctc tttcccacta gcggctcctt
     3301 ttccgacaac cagcacggcg gatccctgcc gcggcgctgt gaacgcagca ttttgattgg
     3361 tatcgttggc cttcaggctc gtcagtcaaa cagacccagg agcagctcag ccggtggcgc
     3421 ccggctttcg ggtaacgccc tggtcccgct ggtttcggct ttgtgcttca ggtgatcaag
     3481 gatggggtcg tttgcgggag agggcgaaat cctacgctaa ggctttggcc aacgatattc
     3541 tccggtaaga ttgatgtgtt cccaggggat aggagaagtc gcttgatatc tagtatgacg
     3601 tctgtcgcac ctgcttgatc gcggccgcga tagctagatc gcgttgctcc tcttctccat
     3661 ccgcgttcca agctgcggaa aggcacccat aagcgtacgc ctggtcgagc aggcgacgcg
     3721 gatcgacgtc cagcgcacga gagaatgcgt ccgccatctg tgcaatgcgt ctaggatcga
     3781 gacaaaggtc gtctctgtca gccggatcgt agaacatatt ggcggcgcca aagcccactt
     3841 caccgaccag accgacggga tctatcacca gccagccgcg actggagaac atgatgtttt
     3901 catgatgcag atcgccatgt agcccacgca gttccgaggc attgctcatc atttgatcgg
     3961 ctataatcgc cgcgtggacg tagtcagttt gacaacctgc gttttgatca tcgcgcgccc
     4021 gctgaaacaa agctgcaaag cgatcccgga tcgggagaag ggcagaaggc aggggttcct
     4081 cagatgcggc atacagcttc gccattagtt ccgctgcaat ttcggtcgcc tggtagtcgc
     4141 cgtgctcggc aacgatgtga gagagcattc gctccccggc atattcgagc aacatcagat
     4201 tgttctcacg accgagcaac cggactgctc ccctcccatt gcgccatacc agatagtcgg
     4261 ccccgcgcag ttcatcagca atgtcttcta taggtttcaa tcccttgacg attgcaggag
     4321 tcccgtctgg caatgaaact ttccaaacga ggctggaaaa ggtgtccgca atgagaacag
     4381 gttgcgaaac gtgccaatga gcaggaaaaa caggcggcat gaacatcaac cccaagtcag
     4441 agggtccaat cgcagataga aggcaaggcg ttcgcggtcg ggggcttcga tccccaatac
     4501 attgaatagg acagcgaagg cgcgctctgc ttcatctggc gctgcccagt tctcttcggc
     4561 gttagcaatc atgagtgcca aatcggcata gcgatctgct gttccgagcc gcccaaggtc
     4621 gatcagaccc gtgcattgaa gagttttagg gtccaccatg aagttcggca tgcagggatc
     4681 accatggcaa acaaccatat cggtgcgctc ttggtcgagc cgcaccggta gctctcgttc
     4741 gacacgagcc aaaagatcga gctgcggcgt actcttgtcc tcgtccggta agaagtcggg
     4801 attgacggca ttgcgggaca ccacatcaac ggcgcgtccg aacattcgcg acagcctgcg
     4861 ctcaaacgga cattgatcaa ccgataggct gtgaacagcg ccaagttgct gccccattga
     4921 cggccacgct ttgagcaaat ccgctccaga cagatcagcc gccggtactc ccggaattgc
     4981 cgttatcacc aagcatgcac cctcctgttc ctcctgccag ttgatcacct cggggcaagc
     5041 cacacctcga cctttgagcc aaatgaggcg gtcacgctct ccagcgagct caccgcggcg
     5101 ggaagcaggt gcgattttcg cgaaggcatg cccgtcacca cgtcgaaaaa caaaatcacc
     5161 agattctccg cctctgacag gcaaccagtc agaatgcgat tcaccaaaaa aaatattagt
     5221 tcgattcaat ggaggttcct tcagttttct gatgaagcgc ggaggtggct caacctgcga
     5281 aaagaaacga gttgctacgt aagtccgaga acatgctttc catggtcttg caccggttgt
     5341 gttccggtct atctctcatt ttaagcggct tttttctcaa atgccaccgg cgatttccag
     5401 ccgagtgctg atgaatcccc taatgatttt tatcaaaatc attaagttaa ggtagataca
     5461 catcttgtca tatgatcaaa tggtttcgcg aaaaatcaat aatcagacaa caagatgtgc
     5521 gaactcgata ttttacacga ctctctttac caattctgcc ccgaattaca cttaaaacga
     5581 ctcaacagct taacgttggc ttgccacgca ttacttgact gtaaaactct cactcttacc
     5641 gaacttggcc gtaacctgcc aaccaaagcg agaacaaaac ataacatcaa acgaatcgac
     5701 cgattgttag gtaatcgtca cctccacaaa gagcgactcg ctg
//
LOCUS       DAZUDJ010000151         5731 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.153, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000151 DAZUDJ010000000
VERSION     DAZUDJ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5731
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.153"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..256
                     /locus_tag="ACHY1N_004892"
     CDS             <1..256
                     /locus_tag="ACHY1N_004892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tetracyline resistance-associated
                     transcriptional repressor TetC"
                     /protein_id="HFS4047042.1"
                     /translation="MPIIGWNELEKISLEYITGKVNAIVSKLIQENQLKAYDDDVLKN
                     LLNGWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK"
     gene            complement(369..1574)
                     /gene="tet(B)"
                     /locus_tag="ACHY1N_004893"
     CDS             complement(369..1574)
                     /gene="tet(B)"
                     /locus_tag="ACHY1N_004893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HFS4047043.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVTFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
     gene            1656..2279
                     /gene="tetR(B)"
                     /locus_tag="ACHY1N_004894"
     CDS             1656..2279
                     /gene="tetR(B)"
                     /locus_tag="ACHY1N_004894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HFS4047044.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            complement(2257..2943)
                     /locus_tag="ACHY1N_004895"
     CDS             complement(2257..2943)
                     /locus_tag="ACHY1N_004895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFS4047045.1"
                     /translation="MANLIRKEVTFESSIAAIGAAMSDISRVKILSALMDGRAWTATE
                     LSSVANISASTASSHLSKLLDCQLITVVAQGKHRYFRLAGKDIAELMESMMGISLNHG
                     VHAKVSTPVHLRKARTCYDHLAGEVAVKIYDSLCQQQWITENGSMITLSGIQYFHEMG
                     IDVPSKHSRKICCACLDWSERRFHLGGYVGAALFSLYESKGWLTRHLGYREVTITEKG
                     YAAFKTHFHI"
     gene            complement(2951..3337)
                     /locus_tag="ACHY1N_004896"
     CDS             complement(2951..3337)
                     /locus_tag="ACHY1N_004896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HFS4047046.1"
                     /translation="MFDVHVVLDNQIGQLALLGKTLGNKGIGLEGGGIFTVGDECHAH
                     FLVEQGKEAKIALEQAGLLVLAIRTPLIRKLKHEKPGELGEIARVLAENNINILVQYS
                     DHANQLILITDNDSMAASVTLPWAIK"
     gene            complement(3330..3650)
                     /locus_tag="ACHY1N_004897"
     CDS             complement(3330..3650)
                     /locus_tag="ACHY1N_004897"
                     /EC_number="1.14.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HFS4047047.1"
                     /translation="MIAVIFEVQIQPDQQTRYLTLAEELRPLLSHVAGFISIERFQSL
                     ATEGKMLSLSWWENEYAVLQWKNHVLHAKAQQEGRESIFDFYKISIAHITREYSFKKD
                     KDNV"
     gene            4094..5299
                     /gene="gltS"
                     /locus_tag="ACHY1N_004898"
     CDS             4094..5299
                     /gene="gltS"
                     /locus_tag="ACHY1N_004898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HFS4047048.1"
                     /translation="MILDASYTLLVACIALLIGMFVVKFTPFLQKNHIPEAVVGGFIV
                     AIVLLIIDKTSGYSFTFDASLQSLLMLTFFSSIGLSSDFSRLIKGGKPLVLLTIAVTI
                     LIAIQNTVGMSMAVMMNESPFIGLIAGSITLTGGHGNAGAWGPILADKYGVTGAVELA
                     MACATLGLVLGGLVGGPVARHLLKKVSIPKTTEQERDTIVEAFEQPSVKRKINANNVI
                     ETISMLIICIVVGGYISALFKDTFLQLPTFVWCLFVGIIIRNTLTHVFKHEVFEPTVD
                     VLGSVALSLFLAMALMSLKFGQLASMAGPVLIIIAVQTVVMVLFACFVTFKMMGKDYD
                     AVVISAGHCGFGMGATPTAIANMQTVTKAFGPSHKAFLVVPMVGAFIVDISNSILIKI
                     FIEIGTYFT"
     gene            5530..5649
                     /locus_tag="ACHY1N_004899"
                     /pseudo
     CDS             5530..5649
                     /locus_tag="ACHY1N_004899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227464.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(5665..>5731)
                     /locus_tag="ACHY1N_004900"
     CDS             complement(5665..>5731)
                     /locus_tag="ACHY1N_004900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047049.1"
                     /translation="LVAATLLTQNLFTHGYVLGKL"
BASE COUNT         1771 a         1182 c         1058 g         1720 t
ORIGIN      
        1 gatgcctatc attggttgga atgaacttga aaaaattagc cttgaataca ttactggtaa
       61 ggtaaacgcc attgtcagca aattgatcca agagaaccaa cttaaagctt atgatgatga
      121 tgtgcttaaa aacttactca atggctggtt tatgcatatc gcaatacatg cgaaaaacct
      181 aaaagagctt gccgataaaa aaggccaatt tattgctatt taccgcggct ttttattgag
      241 cttgaaagat aaataaaata gataggtttt atttgaagct aaatcttctt tatcgtaaaa
      301 aatgccctct tgggttatca agagggtcat tatatttcgc ggaataacat catttggtga
      361 cgaaataact aagcacttgt ctcctgttta ctcccctgag cttgaggggt taacatgaag
      421 gtcatcgata gcaggataat aatacagtaa aacgctaaac caataatcca aatccagcca
      481 tcccaaattg gtagtgaatg attataaata acagcaaaca gtaatgggcc aataacaccg
      541 gttgcattgg taaggctcac caataatccc tgtaaagcac cttgctgatg actctttgtt
      601 tggatagaca tcactccctg taatgcaggt aaagcgatcc caccaccagc caataaaatt
      661 aaaacaggga aaactaacca accttcagat ataaacgcta aaaaggcaaa tgcactacta
      721 tctgcaataa atccgagcag tactgccgtt ttttcgcccc atttagtggc tattcttcct
      781 gccacaaagg cttggaatac tgagtgtaaa agaccaagac ccgctaatga aaagccaacc
      841 atcatgctat tccatccaaa acgattttcg gtaaatagca cccacaccgt tgcgggaatt
      901 tggcctatca attgcgctga aaaataaata atcaacaaaa tgggcatcgt tttaaataaa
      961 gtgatgtata ccgaattcga ttgcgtctca acccctactt cggtatctgt attatcacgt
     1021 gtatttttgg tttcacggaa ccaaaacata accacaagga aagtgacaat atttagcaac
     1081 gcagcgataa aaaagggact atgcggtgaa atctctcctg caaaaccacc aataataggc
     1141 cccgctatta aaccaagccc aaaacttgcc cctaaccaac cgaaccactt cacgcgttga
     1201 gaagctgagg tggtatcggc aatgaccgat gccgcgacag ccccagtagc tcctgtgatc
     1261 cctgaaagca aacggcctaa atacagcatc caaagcgcac ttgaaaaagc cagcaataag
     1321 taatccagcg atgcgcctat taatgacaac aacagcactg ggcgccgacc aaatcggtca
     1381 gacatttttc caagccaagg agcaaagata acctgcatta acgcataaag tgcaagcaat
     1441 acgccaaagt ggttagcgat atcttccgaa gcaataaatt cacgtaataa cgttggcaag
     1501 actggcatga taaggccaat ccccatggca tcgagtaacg taattaccaa tgcgatcttt
     1561 gtcgaactat tcatttcact tttctctatc actgataggg agtggtaaaa taactctatc
     1621 aatgatagag tgtcaacaaa aattaggaat taatgatgtc tagattagat aaaagtaaag
     1681 tgattaacag cgcattagag ctgcttaatg aggtcggaat cgaaggttta acaacccgta
     1741 aactcgccca gaagctaggt gtagagcagc ctacattgta ttggcatgta aaaaataagc
     1801 gggctttgct cgacgcctta gccattgaga tgttagatag gcaccatact cacttttgcc
     1861 ctttagaagg ggaaagctgg caagattttt tacgtaataa cgctaaaagt tttagatgtg
     1921 ctttactaag tcatcgcgat ggagcaaaag tacatttagg tacacggcct acagaaaaac
     1981 agtatgaaac tctcgaaaat caattagcct ttttatgcca acaaggtttt tcactagaga
     2041 atgcattata tgcactcagc gctgtggggc attttacttt aggttgcgta ttggaagatc
     2101 aagagcatca agtcgctaaa gaagaaaggg aaacacctac tactgatagt atgccgccat
     2161 tattacgaca agctatcgaa ttatttgatc accaaggtgc agagccagcc ttcttattcg
     2221 gccttgaatt gatcatatgc ggattagaaa aacaacttaa atgtgaaagt gggtcttaaa
     2281 agcagcataa cctttttccg tgatggtaac ttcacggtaa ccaagatgtc gagttaacca
     2341 ccctttagat tcataaagcg aaaataatgc ggctccaacg tacccaccta aatggaaacg
     2401 gcgttcactc caatctaaac acgcacaaca gattttacgt gaatgtttgg aaggaacgtc
     2461 aattcccatt tcatgaaaat attgaatacc acttaatgtg atcattgaac cattttcagt
     2521 gatccattgc tgttgacaaa gggaatcata gatcttaacg gcaacttcgc cagctaaatg
     2581 atcatagcaa gtacgtgctt ttcgtaaatg cactggcgtg gaaactttgg catgtacgcc
     2641 atggtttaag gagatcccca tcatactttc catcaattca gcaatatctt ttcctgctag
     2701 ccgaaaataa cgatgcttgc cttgagctac tactgtgatt agctggcaat ctaataattt
     2761 agataaatga ctgctcgccg ttgaagctga tatattcgcc acagaactta gctcagtggc
     2821 cgtccaagct cgcccatcca tcaaagcact gagtatttta actcgtgaaa tgtcagacat
     2881 agccgcccct atcgcggcta ttgaggactc aaaggtaacc tcttttcgta ttaaattagc
     2941 catcgcaagt tcactttatt gcccaaggga gcgtaacaga tgcagccata ctatcattgt
     3001 ccgttattaa tatcagttgg ttagcatggt cactgtattg cactaaaata ttaatgttat
     3061 tctccgccaa tactcgtgct atttcgccaa gttcccccgg tttttcatgt tttaacttac
     3121 gaattaatgg tgtccggatc gcaagtacta acagtccagc ttgctctagc gctattttag
     3181 cttcctttcc ttgttcaaca agaaaatgag catggcattc atcaccaacc gtaaatatcc
     3241 ctcccccttc caatccaata cctttattac ctaatgtttt tcctagtaat gctaattgtc
     3301 ctatttgatt atctaaaaca acgtgaacat caaacattat ccttgtcctt tttaaatgaa
     3361 tattcgcgag taatatgagc aatactaatt ttgtaaaaat caaatattga ctctcgccct
     3421 tcttgttgag ctttcgcatg taaaacatga tttttccatt gcagaactgc gtattcgttt
     3481 tcccaccaag atagcgataa catttttcct tctgtagcta gactttgaaa acgttcaatt
     3541 gaaataaaac cagctacatg acttaatagt ggtcttaact cctcagctaa agtcaaatag
     3601 cgagtttgtt ggtcgggttg tatttgcacc tcaaatatta cagcaatcat atttttctcc
     3661 gttattaatc aacaaacaga gtaatccacc cgaaaattaa cacttcgata agcaacgaaa
     3721 tatagaaagg tcatgctgct gttttatgtt gtatatcaca cttctttaaa ttgctcggcc
     3781 tgcgcttatc atgttctcct tctcttataa ttttgtttat tatttatact tttttatttt
     3841 ttgctatcac cgaaaatagt gcggatcccg catggtattt aggtttaccc atcattaaat
     3901 accattgttg ttattttaat ctttttaata tttcatgatt aagatcacac taaaattatg
     3961 accctattaa ctaaaagtta tggataccct aataaaactc attgttaaag attagttaac
     4021 caaagtaact tcatttttca ctattgttaa attgttatag tgaaaattct ggtaaactaa
     4081 tagaggtaaa aaaatgatcc tagatgccag ttatacatta ttagtcgcat gtatcgcgct
     4141 actcatagga atgtttgtcg taaaatttac cccgttccta caaaaaaacc acataccaga
     4201 agccgtcgtt ggtggcttta ttgttgcaat tgttctgtta attattgata aaacatcagg
     4261 ttattcgttt acttttgatg cttcattgca aagtttatta atgctcacat tcttttcctc
     4321 tatcgggcta agttctgact tttctcgact gattaaagga ggaaagccgt tagttctatt
     4381 aactattgca gtaacgatcc taatcgccat tcaaaatact gtcggcatga gtatggctgt
     4441 catgatgaat gaaagtccat ttattggctt aattgcaggt tcaattactc taacaggtgg
     4501 tcatggtaat gccggagcat ggggccctat tctcgctgat aaatatggtg taacaggcgc
     4561 cgttgaatta gcgatggctt gtgcaacact tggattagtg ttgggtggtt tagttggcgg
     4621 ccctgttgcc cgtcatcttt tgaaaaaggt ctctattcct aaaacaaccg agcaagagcg
     4681 cgacactatc gttgaagctt ttgagcaacc aagcgtcaaa agaaaaatca atgcaaataa
     4741 cgttattgaa accatttcaa tgctgattat ctgtattgtt gttggtggct atatcagtgc
     4801 attgtttaaa gatacttttc tgcaactgcc tacttttgtc tggtgtttat ttgtcggtat
     4861 tattatccgt aatacactga ctcatgtatt taaacacgaa gtgtttgagc cgaccgtcga
     4921 tgtattaggt agcgttgctt tatcgctttt cttggcaatg gcgttaatgt cattaaaatt
     4981 tggtcaattg gcaagcatgg cagggccagt attaattatc attgctgtac aaactgttgt
     5041 catggtgcta tttgcctgct ttgtcacctt caaaatgatg ggcaaagatt atgatgctgt
     5101 cgtgatcagc gcgggtcact gtggctttgg tatgggagca acaccaacag caattgcgaa
     5161 tatgcaaaca gtcacaaaag catttggacc atcacataaa gctttccttg tcgttcctat
     5221 ggtcggtgcc tttattgttg atatttcaaa cagtatctta attaaaatat ttattgaaat
     5281 tggtacatac tttacctaat agctacacac tactcggcgt acttctccta acaatttatt
     5341 atagggcagt atgccgagcc gctttcttac cccgtatatt cccctagtca atctatttag
     5401 cttgcacgtt tacgaattaa ttctcgtgac aactaaacca aaatttgaat tatgacgagt
     5461 atatctgatt atttatactt tattcgttag aatagtccgt agaaataaat aatcagtagg
     5521 ctacatggaa tgaaattaag acatctcgat atcttttatg ctgtaatgac ttgtggttcc
     5581 ttaacgcgtg cggctgaagt tttacatatt tctcaacccg cggcgagtaa agcactcaaa
     5641 catgctgagc actgagagat cccctcataa tttccccaaa acgtaaccat gtgtgaatag
     5701 attttgagta agcagggttg cagccacgag t
//
LOCUS       DAZUDJ010000152         5705 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.154, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000152 DAZUDJ010000000
VERSION     DAZUDJ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5705
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.154"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            21..1118
                     /locus_tag="ACHY1N_004901"
     CDS             21..1118
                     /locus_tag="ACHY1N_004901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HFS4047050.1"
                     /translation="MKKLTVAISAVAASVLMAMSAQAAEIYNKDSNKLDLYGKVNAKH
                     YFSSNDADDGDTTYVRLGFKGETQINDQLTGFGQWEYEFKGNRAESQGSSKDKTRLAF
                     AGLKFGDYGSIDYGRNYGVAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNN
                     DFFGLVDGLNFAAQYQGKNDRSDFDNYTEGNGDGFGFSATYEYEGFGIGATYAKSDRT
                     DTQVNAGKVLPEVFASGKNAEVWAAGLKYDANNIYLATTYSETQNMTVFADHFVANKA
                     QNFEAVAQYQFDFGLRPSVAYLQSKGKDLGVWGDQDLVKYVDVGATYYFNKNMSTFVD
                     YKINLLDKNDFTKALGVSTDDIVAVGLVYQF"
     gene            complement(1308..1691)
                     /gene="quuD"
                     /locus_tag="ACHY1N_004902"
     CDS             complement(1308..1691)
                     /gene="quuD"
                     /locus_tag="ACHY1N_004902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein QuuD"
                     /protein_id="HFS4047051.1"
                     /translation="MCDIQMVLERWGAWAANNHEDVTWSSIAAGFKGLIPSKVKSRPQ
                     CCDDDAMIICGCMARLKKNNSDLHDLLVDYYVVGMTFMSLAGKHCCSDGYIGKRLQKA
                     EGIIEGMLMALDIRLEMDIVVNNSN"
     gene            complement(1709..2698)
                     /locus_tag="ACHY1N_004903"
     CDS             complement(1709..2698)
                     /locus_tag="ACHY1N_004903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HFS4047052.1"
                     /translation="MRALLTPEIAPRMGIVLFRPGSELMPLFMQGRVLLEPEPERYSS
                     FASGAVPAASQPLADDPAVRAVFRNEAVIRRAGGVECLESWLLREKGCQWPHSDWHSE
                     NMTTMRHAPGAIRLCWHCDNQLRDQFTERLESMATDNCARWVLSVVRRDLGFDDSHVV
                     TMPELCWWLIRNDLADALPESAARKALRLPKPVVPSVTRESDLVPSVPATSIIQDKAK
                     KVLALKVDPESPESFMLRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGG
                     MGTKAHDLFVLPLCRKHHDELHADTVAFEEKYGSQLELIFRFIDRALAIGVLA"
     gene            complement(2706..3515)
                     /locus_tag="ACHY1N_004904"
     CDS             complement(2706..3515)
                     /locus_tag="ACHY1N_004904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HFS4047053.1"
                     /translation="MNNLMVIDGIEVRRDAYGRYSLNDLHRAAVASGANARTKEPGKF
                     LSSQQTVELVHELTNTQNLGVDPVSVIHGGNERGTYVCKELVYAYAMWISPSFHLKVI
                     RTFDMVTSAPEKLSGQAADKMQAGVILLDFMRRELNLSNSSVLGACQKLQEAVGLPNL
                     APRYAIDAPADAHDGSSRPTLSLSALLKQYGIRLTANQAYHQMVKLGIVEQRERYSRT
                     AINNIKKFWSLTAKGCMFGKNITSPANPRETQPHFFESRFPELLKLLDTVH"
     gene            complement(3535..3924)
                     /locus_tag="ACHY1N_004905"
     CDS             complement(3535..3924)
                     /locus_tag="ACHY1N_004905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFS4047054.1"
                     /translation="MKLILPFPPSVNTYWRHPNKGAFAGKSLISAAGRKFQSAACAAI
                     VEQLRRLPKPTSAPASVEIVLFPPDNRIRDLDNYNKALFDALTHAGVWEDDSQVKRML
                     VEWGPVIPKGKVEITISKYEKTAGAAA"
     gene            complement(3921..4247)
                     /locus_tag="ACHY1N_004906"
     CDS             complement(3921..4247)
                     /locus_tag="ACHY1N_004906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003878599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HFS4047055.1"
                     /translation="MTTLTQCQQQVLDMLISYQQERGFPPTNQEVATMLGYRSVNAAV
                     EHLRALEKKGVITIKRGVARGITLHTAVKDDDSEAVGIIRALLAGEENARLRAAHWLH
                     ERGLKV"
     gene            complement(4244..4897)
                     /locus_tag="ACHY1N_004907"
     CDS             complement(4244..4897)
                     /locus_tag="ACHY1N_004907"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001378271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage N-6-adenine-methyltransferase"
                     /protein_id="HFS4047056.1"
                     /translation="MSNKYCQALVELRNKPAHELKEVGDQWRTPDNIFWGINTLFGPF
                     VLDLFTDGDNAKCAAYYTAEDNALAHDWSERLAELKGAAFGNPPYSRASQHEGQYITG
                     MRYIMKHASAMRDKGGRYVFLIKAATSEVWWPEDADHIAFIRGRIGFELPAWFIPKDE
                     KQVPTGAFFAGAIAVFDKTWKGPAISYIGRDELEACGEAFLAQVRQQAEKLVREMAA"
     gene            complement(4897..5391)
                     /locus_tag="ACHY1N_004908"
     CDS             complement(4897..5391)
                     /locus_tag="ACHY1N_004908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HFS4047057.1"
                     /translation="MIMSLLNEVQKFIEAHPGCTSGDIADAFAGYSRQRVLQSASKLR
                     QSGRVAHRCEGDTRRHFPRLTERAQEPEPQPVRETRPVRNFYVGTNDPRVILCLTRQA
                     EELESRGLYRRAATVWMAAFRESHSQPERNNFLARRERCLRKSSKRAASGEEWYLSGN
                     YVGA"
     gene            complement(5388..>5705)
                     /locus_tag="ACHY1N_004909"
     CDS             complement(5388..>5705)
                     /locus_tag="ACHY1N_004909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdfO"
                     /protein_id="HFS4047058.1"
                     /translation="AAECDGEVVRPKEPNWTAWANEIRLMCVQDGRTHKQICEMYSRV
                     SRDPFWCRNVLSPSKLREKWDELSLRLSPSVSTYTEKREDPYFKSSYDNVDYSQIPAG
                     FRG"
BASE COUNT         1374 a         1588 c         1327 g         1416 t
ORIGIN      
        1 ttcaaaaaaa agggctcacg atgaaaaaat taacagtggc aatttctgct gtagctgcat
       61 cagtactgat ggcgatgtct gctcaggcag ctgaaattta taataaagac agtaacaagc
      121 tggatctgta cgggaaagtt aatgccaagc actacttttc ctctaacgat gcagatgatg
      181 gtgatactac ttatgttcgt ctgggcttca aaggcgaaac ccaaatcaac gatcagctga
      241 ctggtttcgg tcagtgggaa tatgaattca aaggcaaccg cgctgaatct caaggttcct
      301 ccaaagacaa aacccgtctt gcatttgcag gcctgaaatt cggtgactac ggctcaatcg
      361 attacggccg taactacggt gtagcatacg acatcggtgc gtggactgac gttctgccag
      421 aattcggtgg cgatacctgg acccaaacag atgtgttcat gactggtcgc accactggtg
      481 ttgcaaccta tcgtaacaac gacttctttg gtctggttga tggtctgaac tttgctgctc
      541 agtaccaagg caaaaacgat cgtagcgatt tcgataacta caccgaaggt aacggtgatg
      601 gcttcggttt ctctgctacc tatgaatacg aaggattcgg tatcggtgca acttatgcga
      661 aatctgatcg taccgacact caagttaatg cagggaaagt tcttcctgaa gtatttgctt
      721 ccggtaaaaa tgcagaagtt tgggccgcag gtctgaaata tgacgctaac aacatttacc
      781 tggccactac ctattctgaa acccagaata tgactgtatt tgctgatcac ttcgttgcta
      841 ataaagctca aaacttcgaa gctgttgcac aatatcagtt cgatttcggt ctgcgtccgt
      901 ccgttgctta cctgcaatct aaaggtaagg atcttggagt atggggcgat caggacttag
      961 tcaaatatgt tgatgtaggt gcaacctatt acttcaacaa aaatatgtct actttcgttg
     1021 attacaaaat caacctgctt gacaaaaatg acttcactaa agcactcggt gtaagcactg
     1081 atgacatcgt tgctgtaggt ctggtttacc agttctaatc tgattacgaa aaagatatgt
     1141 tgcgggaggc gttgcctccc caacatataa gtggctccct caagccactt cctttaggag
     1201 cacaaccttg cttctaacta tataaacctt ctgttatata ttacccttta tttttggggg
     1261 cgttgcaacg ccccattttt aataactttc agtaaacaat tggcatatta attagagtta
     1321 ttaacaacga tatccatctc taaccggata tctaatgcca ttaacatccc ttcaattatg
     1381 ccctcagcct tctgtaacct tttcccgata taaccatcag agcagcaatg cttacctgcc
     1441 agtgacatga atgtcatacc gactacataa taatctacta ataaatcgtg caaatcgctg
     1501 ttgttctttt tcagacgggc catgcacccg caaatgatca tcgcgtcatc gtcacaacat
     1561 tgcgggcgag attttacttt tgaaggaatt aatcccttaa aaccggcggc aatggacgac
     1621 caggtcacat cttcatgatt attagccgcc cacgctcccc aacgttcaag aaccatctga
     1681 atatcacaca ttaactttct ccacaaaatc aggccagcac accaatcgcc agtgcgcgat
     1741 cgataaaacg aaatatcagc tccagctggg agccatactt ctcttcaaat gccacggtat
     1801 ccgcatgcag ttcgtcgtgg tgttttctgc acaaaggcag cacaaaaagg tcatgcgctt
     1861 ttgtacccat tccaccctga ccatggccta tcagatgatg cggatcatca gctggctttc
     1921 cacaacatgc acacggctgt gtcttaaccc agcgcgtgta cttttcatta acccagcggc
     1981 gacgttttgg gcgtaacata aaagactccg gcgactccgg atccactttc agcgccagca
     2041 cctttttcgc cttatcctgg atgatgctgg tggcaggaac cgaaggcaca aggtcacttt
     2101 cccgggtaac agacggcaca acaggcttcg gtaatctcag tgccttacgg gctgcacttt
     2161 ccggtaaggc atccgccaga tcattacgaa tcagccacca gcacagttcc ggcattgtca
     2221 caacgtgact gtcatcaaaa ccgagatccc gacgcacaac agacaacacc cagcgggcac
     2281 agttatccgt tgccattgat tccagccgtt ccgtgaactg atcgcgcagc tggttatcgc
     2341 agtgccagca cagacggatt gcacccggag cgtgtcgcat tgtggtcatg ttctcgctgt
     2401 gccagtcgga atgaggccac tggcagcctt tttcacgaag taaccagctt tcaagacatt
     2461 ccacgccacc agcacgacgg atcactgcct cattgcggaa cacggcccga acggcaggat
     2521 catccgccag cggttgtgat gccgccggaa cggcaccact ggcgaaagat gaataacgct
     2581 ccggctcagg ctccagcagg acacgcccct gcataaacag gggcatcagc tctgaacctg
     2641 gcctgaacaa tacgatcccc atacgcgggg caatttcagg ggtcagtagt gctctcacgg
     2701 tcacctcaat gaacggtatc gagcagcttt aacagctcag ggaatcggga ttcgaagaaa
     2761 tgcggctgcg tctcgcgcgg atttgcggga ctggtgatgt tcttgccgaa catgcaacct
     2821 ttcgctgtca gcgaccagaa ttttttgatg ttgttaatcg ctgtacggct gtatcgttcg
     2881 cgctgctcga cgatccccag tttcaccatc tggtgatatg cctgattagc cgtcaggcgt
     2941 ataccatact gtttcagcag tgcactcagt gacagtgtcg ggcgacttga gccatcgtgt
     3001 gcatcagcag gagcatcaat ggcatagcgc ggtgccagat tcggtaagcc aacagcctcc
     3061 tggagtttct gacaggcacc aagcactgaa gagttagaca ggtttaactc ccggcgcata
     3121 aaatccagca ggatcacgcc agcctgcatc ttgtcagcag cctgtccgga taatttttcc
     3181 ggtgcgctgg ttaccatatc gaaagtacgg atcaccttca gatggaatga cgggctgatc
     3241 cacattgcat aggcatacac cagttccttg cagacatacg ttccccgttc atttccccca
     3301 tgaatcacac tcaccgggtc aacacccaaa ttctgggtgt tggtcaattc atgaacaagc
     3361 tcaacagttt gttggctgga aagaaacttt cccggctcct tggttctggc atttgcacca
     3421 gatgctactg ctgcgcgatg cagatcgttc aggctgtaac gcccataagc atcacgacga
     3481 acttcaatac catcaatgac catcagatta ttcatacttc gtttctcctc ttgatcaggc
     3541 ggctgcaccc gccgttttct cgtacttact gatagtgatc tcgaccttcc ctttcgggat
     3601 aaccggtccc cactccacca gcattctttt cacctgactg tcgtcttccc acacacccgc
     3661 atgggtcagg gcgtcaaaca gcgccttgtt atagttgtcc agatcgcgga tccggttatc
     3721 cggaggaaac aacacgatct ccactgaagc aggtgccgac gttggtttcg gcagacgacg
     3781 taactgctca actattgctg cgcacgccgc gctctggaat ttgcgccccg ctgcgcttat
     3841 cagactctta ccagcaaacg cccctttgtt ggggtgtcgc cagtacgtgt tcacgctggg
     3901 agggaaaggc aagatcagct tcatactttc aggcccctct catgtaacca gtgggctgca
     3961 cgcagcctgg cgttttcctc accggcaagc agtgcgcgga taatcccgac cgcctcgctg
     4021 tcgtcgtcct tcaccgcggt atgaagagtt atcccccggg ccacgccacg ctttatcgtg
     4081 atgacgcctt ttttctccag tgcgcgaaga tgctccaccg ctgcattcac cgaacggtat
     4141 cccagcatgg ttgccacctc ctgattggtt ggcggaaagc cacgttcttg ctggtaagaa
     4201 atcagcatat ccagcacctg ctgctggcat tgagttaacg tcgtcatgcc gccatctccc
     4261 tgaccagttt ttccgcctgc tggcgaacct gcgccagaaa ggcctcacca catgcctcaa
     4321 gttcatcgcg cccgatgtag ctgattgccg gtcccttcca ggtcttgtcg aaaacagcaa
     4381 tagcaccagc gaagaaagcg cctgtcggca cctgcttctc atccttcggg ataaaccagg
     4441 caggcagttc aaaaccaata cgcccgcgaa taaaagcaat atggtccgca tcttccggcc
     4501 accacacttc gctggtggca gctttgatca ggaaaacata gcgcccgccc ttatcacgca
     4561 tggcactggc atgtttcatg atgtaacgca tgccggtgat gtattgcccc tcatgctgac
     4621 tggcgcggct gtatggggga ttaccaaagg cagcaccttt aagctccgca agacgttctg
     4681 accagtcatg cgccagcgcg ttatcttccg ccgtgtaata cgcggcacat ttggcgttat
     4741 caccgtcagt aaacagatcc agaacaaacg ggccaaacag ggtgttaatt ccccagaaaa
     4801 tgttgtccgg cgtgcgccac tgatcgccca cttccttcag ttcatgggct ggtttgttcc
     4861 gcagttccac cagcgcctgg caatatttat tactcattaa gcccccacgt aattccctga
     4921 cagataccac tcttcacccg atgcagcgcg cttgctgctt ttccgtaagc accgctcacg
     4981 acgcgccaga aaattgtttc gttctggctg ggagtggctt tcacggaatg ccgccatcca
     5041 caccgttgca gcacgacggt ataagcccct ggactccagt tcttcagcct ggcgggtcag
     5101 gcacaaaatc acccgtggat cgttagtgcc gacatagaaa ttgcgcacag gtctggtttc
     5161 tcgaactggt tgtggttccg gttcctgcgc tctctcagtc aggcgcggga aatgtctgcg
     5221 tgtatctcct tcacaacggt gagccacacg cccactctga cgtaacttgc ttgctgactg
     5281 cagaacgcgc tgccgtgagt aacctgcaaa agcatccgca atgtctccgg aagtacatcc
     5341 cggatgggct tcaatgaatt tctgaacttc attcaaaaga ctcatgatca ccccctgaat
     5401 cctgccggga tctggctgta gtccacgttg tcgtaactgg atttgaagta cgggtcttcg
     5461 cgtttttcgg tgtacgtgct gacggacggt gataagcgca gggaaagctc atcccatttt
     5521 tcccgcaact tcgacgggct gagcacgtta cggcaccaga acggatcgcg gctgacgcgg
     5581 ctgtacatct cgcagatttg tttgtgagta cgaccatcct gcacacacat caggcgaatt
     5641 tcgtttgccc aggctgtcca gttcggttct ttgggacgaa ccacctcgcc gtcacattcg
     5701 gcggc
//
LOCUS       DAZUDJ010000153         5569 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.155, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000153 DAZUDJ010000000
VERSION     DAZUDJ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5569
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.155"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            17..709
                     /locus_tag="ACHY1N_004910"
     CDS             17..709
                     /locus_tag="ACHY1N_004910"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006235 - dTTP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFS4047059.1"
                     /translation="MQSITPPLIAVIGSDGSGKSTVCEHLITVVEKYGAAERVHLGKQ
                     AGNVGRAVTKLPLMGKSLHKTIERNQVKTAKKLPGPVPALVITAFVARRLLRFRHMLA
                     CRRRGLIVLTDRYPQDQIPGAYDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKPDL
                     VIKLNVDLEVACARKPDHKRESLARKIAITPQLTFGGAQLVDIDANQPLEQVLVDVEK
                     AITDFMTARGYH"
     gene            complement(758..2257)
                     /gene="pitB"
                     /locus_tag="ACHY1N_004911"
     CDS             complement(758..2257)
                     /gene="pitB"
                     /locus_tag="ACHY1N_004911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitB"
                     /protein_id="HFS4047060.1"
                     /translation="MLNLFVGLDIYTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMQPQLAVVMAAFFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSTHGLAMVFSMLL
                     AAIIWNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLI
                     VSPIVGLVIAGGLIFLLRRYWSGTKKRDRIHRIPEDRKKKKGKRKPPFWTRIALIVSA
                     AGVAFSHGANDGQKGIGLVMLVLVGIAPAGFVVNMNASGYEITRTRDAVTNFEHYLQQ
                     HPELPQKLIAMEPPLPAASTDGTQVTEFHCHPANTFDAIARVKTMLPGNMESYEPLTV
                     SQRSQLRRIMLCISDTSAKLAKLPGVSKEDQNLLKKLRSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVAMTIGEKIGKRGMTYAQGMAAQMTAAVSIGLASYIGMPVSTTHVL
                     SSAVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIFLSGGLYWIALQLI"
     gene            complement(2549..4408)
                     /gene="gss"
                     /locus_tag="ACHY1N_004912"
     CDS             complement(2549..4408)
                     /gene="gss"
                     /locus_tag="ACHY1N_004912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HFS4047061.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVF
                     RSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQ
                     AFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQ
                     WTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLEN
                     KGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLH
                     ATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNAD
                     SASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEE
                     NYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQ
                     IREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLF
                     PHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNI
                     YQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKK"
     gene            4613..5479
                     /gene="yghU"
                     /locus_tag="ACHY1N_004913"
     CDS             4613..5479
                     /gene="yghU"
                     /locus_tag="ACHY1N_004913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HFS4047062.1"
                     /translation="MTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIP
                     ALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGG
                     FGHFYHYAPMKIEYAINRFTMEAKRLLDVLDKQLAQHKFIAGDEYTIADMAIWPWFGN
                     VVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDAS
                     DFETNTEDKRQG"
BASE COUNT         1410 a         1443 c         1371 g         1345 t
ORIGIN      
        1 attaaaggat atattcatgc agtcaataac acctccatta attgccgtta ttggtagcga
       61 tggttcaggc aagtcaacgg tgtgtgaaca tcttattacc gttgtcgaaa aatatggtgc
      121 tgccgaaaga gttcatttag gaaaacaggc cggaaatgtc ggtcgtgcag tgacaaaatt
      181 accgttgatg ggaaaatcct tacataaaac aattgaacga aatcaggtga aaacagcaaa
      241 aaaattgcct ggaccagttc cggcgctggt aattacagcg tttgtcgccc gtcgcttact
      301 gcgctttcgt catatgcttg cctgtcgtcg tcgcgggtta attgttctaa ccgaccgtta
      361 tcctcaggac caaattcctg gcgcttacga tggtacggtg ttcccaccta acgttgaagg
      421 tggtcgtttt gtctcatggc tggcaagcca ggaacgtaaa gcgtttcact ggatggcgag
      481 ccataagcct gatctggtca tcaaactcaa tgttgacctt gaagttgcct gtgcacgtaa
      541 acccgaccat aaacgggaat cgctggcgag gaagattgcc ataacgccac agttaacctt
      601 tggtggtgca caactggttg atatcgatgc caatcagcca ctggaacagg tgttggttga
      661 tgtagaaaaa gcgattacgg attttatgac cgcgcgtggt tatcactagt caaaaatgga
      721 aatgcccgat cgccaggacc gggcattttc aggaaggtta aatcaactgc aatgctatcc
      781 agtacagccc accagaaaga aaaattgccg ccggtaaagt aaacacccac gccatcagga
      841 tgctggttac cgttttacgc tgtaacccac cgccgtccac caccatcgtc cctgctaccg
      901 cagacgagag gacgtgtgtt gtggagacag gcatcccaat ataactggca aggccgatag
      961 acactgccgc cgtcatttgt gccgccatgc cttgcgcata cgtcatgccg cgcttaccaa
     1021 tcttctcacc gatggtcatc gctacacgac gccagccaat catggtgcca atgccgagcg
     1081 ccagtgctac cgccatgatg atccacaccg gagcgtactc aatggtgctt aacatatcgc
     1141 tgcgcagttt tttcagcagg ttctggtctt ctttactgac gcctggcagt ttcgccagct
     1201 tcgcggaggt atcagagatg cacagcataa tgcggcgcag ctggctgcgc tgactcacgg
     1261 ttaacggctc gtaactttcc atattgcctg gcagcatcgt tttaacgcgc gcaatagcat
     1321 caaaggtatt tgccggatga cagtgaaact ctgttacttg cgtgccatca gtcgatgctg
     1381 caggcaatgg aggttccatc gcaatcaact tctgcggcag ttcaggatgc tgttgcaggt
     1441 agtgttcgaa gttggtaacg gcatcgcggg tacgggtaat ttcatagccg gacgcattca
     1501 tattgacgac gaagccagca ggggcaatcc ccaccagtac cagcattacc aggccgatcc
     1561 ctttctgtcc gtcgttcgcg ccgtgcgaaa acgccacgcc cgcagcggaa acaatcagcg
     1621 caatacgcgt ccagaatggc ggtttacgtt tgcctttttt ctttttgcga tcttccggaa
     1681 tgcggtgaat acggtcacgc tttttcgtcc cgctccagta gcgtcgcagc aggaatatca
     1741 ggcctcccgc aatgaccagg ccgacgatag gggaaacaat cagcgaggag aaaattttgg
     1801 tcacttcacg caggtttaac gcatccatca ccgatgagcc ggttaacagc gcgttggtta
     1861 aaccgatgcc gataatcgca ccaatcaagg tgtgcgaact ggaggccggt aaaccgaaga
     1921 accacgttcc caggttccag ataatcgccg ccagcagcat ggaaaagacc atcgccaggc
     1981 cgtgggttga ccccatattc agcaacaaat cggttggcaa catatggaca atggcatagg
     2041 caacgctaag tccgcccaat aacacgccaa aaaagttaaa aaatgccgcc atcaccacag
     2101 caagttgtgg ttgcatggca cgagtataaa taacggttgc caccgcattc gccgtgtcat
     2161 gaaaaccatt gattgcttcg tagaacaaca caaatgccag agcaagcaat aacaaaagcc
     2221 ctgtgtatat atcaaggcca acaaataaat ttagcatata ttagattacg ccattttgaa
     2281 tttacgaacg gacgcattat cagtgacttt aacggcatgg gcaaagtgaa atatcatttt
     2341 ttaacgataa aaagagtgtt atttcttgtg tatcagacaa taagcattca ttcaaaacct
     2401 ttagaaataa tcaaaacaca ggtattccac tggttaatat attcacatat gaaatgaata
     2461 aatattggaa tatataaata ttgaatattt tgattaatcc ccgtactgat tattcttcat
     2521 aatcagtacg gggttgctac aacatgtatt actttttcac cacaattaac ggttcaatat
     2581 cactctcttt tttgatgacc agtgattcat caccgcgcaa acacgtccca ccgtagttgc
     2641 cgccaacggt gaaggtacat acctgaatgt atttaccgtc cactttcggc aaacaccaca
     2701 gttgctgata gatgtttttc tgctcggcaa atttaccgct ggttttgtcc agcacctctt
     2761 catgatggct gacgaggtcg atattgctgc cacagcgacc ggcgatcggt ttcactgcgt
     2821 aacctgtttt caccagttca tcattaacag tgaaatcggt atccagcagg taacgatggt
     2881 gcgggaacag cgaccagagg atcggcagaa tcgctttgtt gccggggatc accgtccaca
     2941 gcggctcaaa gaccagcact tccgggcgca gcaatacgtc gataagacgc acttcgtttt
     3001 gcggatgacc ggtacggatt ggcaccgcag caaactcacg gtcgctaact tcacgaatct
     3061 gatcaaacgc ggtttcccac gcccaggttt tccacacgca gttaaccagt cgcccttccc
     3121 catcaatcag ttgcccggca gcatcccagc ccagttcatc cagcccgcgc aagatacgcg
     3181 tttcaaagcc cgcctggtgc agcgcctgct ccataaactg cgcgtgatag ttttcctcga
     3241 tatctttgtc ctgcatgata tggacaaacg gacgtgcacg actgtgtttc caggcaccag
     3301 ccagttcgtt aatcagccct tccgccggat tgaagccgtt gcctttatag ccctgctccg
     3361 cccaacgttc gaggatcaag cccgcttcgg tatgacatga ggcagagtcg gcgttgtact
     3421 cgtaaacctt cagaccacgc tcatccatgc agaaatccat acgaccggtg atcatatggt
     3481 gacggcgacg ctgccaggag agacgcaaac gtggccagag gattttcggg atgtcgaaca
     3541 gcgccagcag gttgtcatct ttcagcacct tgtcggttgc gtgaagatac atcaggtgca
     3601 gctcgttggt ggctttaatt agctcctgct cggcactctc ggtaatggtg tagtaatgat
     3661 aaggatcctg attgatcacc tgaccgttgg cctgcacata ggcgttttgc agcggatctt
     3721 tttcatccag ccatttaccg tcaaactggc ctttgttttc caggcgcgct ccgctgattt
     3781 tcagcagctc gcctgcaatt tccggctgcg gtaagctgta ttcagtatct tccgtctgga
     3841 tcatccagcc cagaatggtg gtgtcatcaa aagtgtcttt cagggtatag cagccgtttt
     3901 cgaccaccat ctccagctca cgcgtccact gttgcccttg cggcaacggg gaatgaatca
     3961 cgttctgttc cgcaatacgg actttgttgc catgcaattg ggtaatgatg gcgacatggc
     4021 cagtgtcttt aaattcaccg cctttatccc agataagaag cgcacccgcg accggcgcac
     4081 gcggcgagcc gttaggaaat gcctgcaatg gcaggatgtt gtcattaacc acttctcgca
     4141 ggaagcgcag cgagaaaatc tcccacgcca tacccacgtc agtaaagacc acaccgtaat
     4201 tcagaaagag aaaacggcga gcaaattcaa cgcattgcca cttgtggccc atatattcgt
     4261 cgtcgatata gctacggaat acggcgtcat cttcgtattc ctgcggatcg agagaactgt
     4321 aatctgaaga gtagattgct accccacctg gggcgtagcc caataatgtc ccgaacgggg
     4381 catcctggct ggtcgttcct ttgctcatca ctttaccttt aacaatacaa cctaagcagt
     4441 tggcgtaatt gttgtgctct gattacctgc tcagcgacat taaccggaca gaggtcagac
     4501 taatcataca cctcatcgca gcggctggcg caaagggtta aaaaattcac attctgtaca
     4561 gcaagtgacc tgctacactg cttcaacact accactcaga aggcaactca ctatgacaga
     4621 caatacttat cagcccgcga aagtctggac gtgggataaa tccgctggcg gcgcgttcgc
     4681 caatatcaat cgcccggttt ctggtccgac gcatgaaaaa acgctgcccg ttggcaaaca
     4741 cccattgcaa ctttattcgc tgggaacgcc gaacggtcag aaagtaacga ttatgcttga
     4801 ggagctgctg gcgctgggcg ttactggtgc agagtacgac gcctggctga ttcgtattgg
     4861 cgatggcgat caattctcca gcggctttgt cgaagtgaac ccaaactcga agatcccggc
     4921 gctgcgcgat catacgcata atccgccgat ccgcgtgttt gaatctggtt cgatcctgct
     4981 ttatctggcg gagaaatttg gctacttcct gccgcaggat ttggcaaagc gtactgaaac
     5041 gatgaactgg ctgttctggt tacagggcgc ggcaccgttc ctcggcggtg gttttggtca
     5101 cttttaccat tacgcgccga tgaaaattga gtacgccatc aaccgcttta ccatggaagc
     5161 caaacgtctg ctcgacgtgc tggataagca actggcgcag cataagttta ttgcgggcga
     5221 tgagtacacc attgcggata tggcgatttg gccgtggttt ggcaatgtgg tgttaggcgg
     5281 cgtgtatgat gccgcagagt ttcttgatgc gggcagttat aagcatgtac aacgctgggc
     5341 gaaagaagta ggcgaacgtc cggcggtgaa acgtgggcgt attgttaacc gcaccaacgg
     5401 accgctgaat gagcagttgc atgagcgcca tgacgccagt gatttcgaga cgaatacgga
     5461 agataagcgt caggggtaag ggttggtgtt cgtcgcagca agccatccag gccggataag
     5521 gcgttcacgc cgcatccggc aatcgtgcac aatgcctgat gcgacgctg
//
LOCUS       DAZUDJ010000154         5440 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.156, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000154 DAZUDJ010000000
VERSION     DAZUDJ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5440
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.156"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..220)
                     /gene="ymfM"
                     /locus_tag="ACHY1N_004914"
     CDS             complement(<1..220)
                     /gene="ymfM"
                     /locus_tag="ACHY1N_004914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor YmfM"
                     /protein_id="HFS4047063.1"
                     /translation="MNSLTTHYRRSQLIALPVPGGKAKVEYCYAVNVPGGRVIVTHSF
                     AEWAVGDFNRQKETVLCDKLTAGSKITTE"
     gene            complement(217..768)
                     /gene="ymfL"
                     /locus_tag="ACHY1N_004915"
     CDS             complement(217..768)
                     /gene="ymfL"
                     /locus_tag="ACHY1N_004915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmfL"
                     /protein_id="HFS4047064.1"
                     /translation="MGKHHWKVEKQPEWYVKAVRKTIAALPGGYAEAADWLDVTENAL
                     FNRLRADGDQIFPLGWAMILQRAGGTHFIADAVAQSANGVFVSLPDVEDVDNADINQR
                     LLEVIEQIGSYSKQIRSAIEDGVVEPHEKTAINDELYLSISKLQEHAALVYKIFCISE
                     SNDARECAAPGAVACRDCGETNA"
     gene            complement(761..1021)
                     /locus_tag="ACHY1N_004916"
     CDS             complement(761..1021)
                     /locus_tag="ACHY1N_004916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001191680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4047065.1"
                     /translation="MQSPLRNVRKAHGFTLQHVAAGVQVNPATLSRIERLEQIPSIEL
                     AERLANFFKGEVSEMQILYPARFQSSQNQNGFKPQEQEVNRG"
     gene            1119..1811
                     /locus_tag="ACHY1N_004917"
     CDS             1119..1811
                     /locus_tag="ACHY1N_004917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001358750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFS4047066.1"
                     /translation="MNIGNRVRQLRQAKNMKIADLAEAIGVDAANISRLETGKQKQFT
                     EQTLSNIAKSLGVDIADLFTSAHKSNTVYKNSNNEDVAQVKDVFRIEMLDISASAGNG
                     LIQGGDVIDVIHAIEYRTDNAVSMFGGRPANHIKVINVRGDSMCPTIEPGDLIFVDVS
                     INQFDGDGIYVFGFDDKIYVKRLQMIPDKLLVISDNQIYREWGITSENEHRFMVFGKV
                     LISQSQTLKRHN"
     gene            complement(2131..2646)
                     /locus_tag="ACHY1N_004918"
     CDS             complement(2131..2646)
                     /locus_tag="ACHY1N_004918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047067.1"
                     /translation="MIAELTAAMTAIRETAQIAKLMNEAKTQAEVNAAIGELNSKLAS
                     IQRECVSLVELVGSYQEINASLKAKIAEFENFEAQTEGYILNQLESGTFVYSKEVIVN
                     GGSITMHLCPKCFGQKIVSILQPFPVSEDELFHKSRCLHCENKFLMNKNPDYVSPPSI
                     EELSRKLNGNL"
     gene            2791..3102
                     /locus_tag="ACHY1N_004919"
                     /pseudo
     CDS             2791..3102
                     /locus_tag="ACHY1N_004919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3117..3479
                     /gene="yfdP"
                     /locus_tag="ACHY1N_004920"
     CDS             3117..3479
                     /gene="yfdP"
                     /locus_tag="ACHY1N_004920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000135678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YfdP"
                     /protein_id="HFS4047068.1"
                     /translation="MASERSTDVQAFIGELDGGVFETKIGAVLSEVASGVMNTKTKGK
                     VSLNLEIEPFDENRVKIKHKLSYVRPTNRGKISEEDTTETPMYVNRGGRLTILQEDQG
                     QLLTLAGEPDGKLRAAGR"
     gene            3545..4369
                     /locus_tag="ACHY1N_004921"
     CDS             3545..4369
                     /locus_tag="ACHY1N_004921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdQ family protein"
                     /protein_id="HFS4047069.1"
                     /translation="MSQNLDATAINQIHALISAQGVNEIISKIGADAVALPENFRIHD
                     LEKFNLNRFRFRGALSTASIDDFTRYSKDLADEGTRCFIDADNMRAVSVLNLGTIDEP
                     GHADNTATLKLKKTAPFSALLSVNGERNSQKSLAEWLEDWADYLVGFDANGDAIQATK
                     AAAAVRKITIEANQTADFEDNDFSGKRSLMESVEAKTKDIMPVAFEFKCVPFEGLKER
                     PFKLRLSIITGDRPVLVLRIIQLEAVQEEMANEFRDLLVEKFKDSKVETFIGTFTA"
     gene            4497..5033
                     /gene="yfdR"
                     /locus_tag="ACHY1N_004922"
     CDS             4497..5033
                     /gene="yfdR"
                     /locus_tag="ACHY1N_004922"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HFS4047070.1"
                     /translation="MSFIKTFSGKHFYYDKINKDDIDINDIAVSLSNICRFAGHLSHF
                     YSVAQHAVLCSQLVPQEFAFEALMHDATEAYCQDIPAPLKRLIPDYKRMEEKIDAVIR
                     EKYGLPPVMSTPVKYADLIMLATERRDLGLDDGSFWPVLEGIPATEMFNVIPLAPGHA
                     YGMFMERFNDLSELRKCA"
     gene            5024..5386
                     /locus_tag="ACHY1N_004923"
     CDS             5024..5386
                     /locus_tag="ACHY1N_004923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047071.1"
                     /translation="MRMNVFEMEGFLRGKCVPRDLKVNETNAEYLLRKFDALEAKCAA
                     LENKIIPVSAELPPANESVLLFDANGEGWLIGWRSLWYTWGQKETGEWQWTFQVGDLE
                     NVNITHWAVMPKAPEAGA"
BASE COUNT         1508 a         1268 c         1234 g         1430 t
ORIGIN      
        1 actccgtagt gatctttgaa ccagcggtta acttgtcgca aaggactgtc tccttctgcc
       61 ggttaaaatc acccacagcc cactctgcaa agctgtgggt tacaattacc ctgccacctg
      121 gtacattaac tgcatagcaa tactccacct tcgcttttcc acccggtaca ggaagcgcaa
      181 tcagttgcga gcgacggtag tgtgttgtta aactgttcat gcgttagttt ctccacagtc
      241 acgacacgcc acggcgcccg gagctgcaca ctcgcgggcg tcattacttt ctgaaatgca
      301 aaaaattttg tagaccagtg ctgcatgctc ctgcagcttc gaaattgaga ggtacagctc
      361 gtcgttaatt gctgtcttct catgcggttc cactacaccg tcttcaattg ctgaacgaat
      421 ctgttttgaa taactgccga tctgttcaat gacctccagc aggcgttggt tgatatcggc
      481 gttgtccaca tcctcgacat caggaagaga cacaaagacg ccatttgcag actgcgccac
      541 agcgtcagca atgaagtgag ttccaccagc acgttgcaaa atcattgccc atcccagcgg
      601 gaaaatctga tcgccatcgg cacgaaggcg gttaaataat gcgttctctg ttacatccag
      661 ccagtcagca gcttcagcgt acccccccgg caacgctgcg atagtttttc tgacagcttt
      721 cacgtaccac tcaggctgtt tttctacttt ccagtgatgc ttacccacgg ttcacctcct
      781 gttcctgtgg tttaaaccca ttctggtttt ggctagattg aaaacgtgcc ggataaagaa
      841 tctgcatttc gctgacttca cccttaaaaa aattggctaa acgttctgca agctcgatag
      901 atggaatctg ctccagcctc tcaatacgac tcaacgtcgc tggattgact tgaacacccg
      961 cagcaacatg ctgcaaagtg aaaccatgcg ccttacgcac atttcgtaat ggtgattgca
     1021 tacgtcctcc aaatattgcg cgttatgcat gttatttcac gcaattattt tgcgcaagtt
     1081 gatttgctta tcacgcaata aagaaatgta ataaacgcat gaacatagga aaccgagtca
     1141 gacaacttcg ccaagcgaag aacatgaaaa tcgccgatct cgctgaagcg ataggagtag
     1201 atgcggcgaa catctcgcgc ttagaaacgg gtaagcaaaa acaatttacc gaacaaacac
     1261 tgagtaatat tgccaagagc ttaggtgttg atattgctga tctctttacc tctgcccaca
     1321 aaagtaatac tgtatataaa aacagtaata atgaggatgt tgcgcaggtg aaggatgtgt
     1381 tccgtattga aatgctggat atcagtgcca gtgcgggaaa tggccttatc cagggcggtg
     1441 atgtcattga tgtgattcat gccatcgaat acagaactga taatgctgta tcaatgttcg
     1501 gcggacgacc agccaatcac atcaaagtta tcaacgttcg tggggacagt atgtgtccaa
     1561 ccattgagcc aggagatctc atcttcgttg atgtcagcat caatcagttt gatggtgatg
     1621 gtatatatgt ctttggtttt gatgacaaaa tatacgttaa aagacttcaa atgattcctg
     1681 acaaactgct ggtgatttct gataaccaga tttaccgtga atggggaatt actagcgaaa
     1741 acgaacaccg attcatggtc tttggaaagg tcttaatcag tcagtcgcaa acccttaaga
     1801 gacataatta acctcaatat cccatccatc ggccaccgaa aggtggcttt ttattaccta
     1861 taaatttgca tatcacgcaa atatcacttg catatctcgc aatttaattt tatcttttgt
     1921 tccagaccaa ctacaggatt acaacaaaat ctggttgcaa cacggtgcat gtgtcgtaag
     1981 cagtcagtaa atgtcaaaaa cgaacaggca ggacgcccac gaagtagccg cctggggcat
     2041 atgaagtcca ggatgattcg ttagcaacaa aaaagcgccc tacaggacgc ttagctcttt
     2101 aacaatctgg atatccacaa cagtagtaat ctacagattg ccgttaagtt ttctggacaa
     2161 ctcctcaatg gatggaggcg atacgtaatc cggattttta ttcatcagaa acttattttc
     2221 acagtggagg cacctgcttt tatgaaaaag ctcatcttcg ctaaccggga atggttgaag
     2281 tatcgatact atcttttgtc caaaacattt tgggcaaaga tgcatggtta tgctgccacc
     2341 gttcacgatt acctccttcg agtatacaaa agtacccgac tcaagttggt taaggatata
     2401 gccttccgtc tgagcctcaa agttttcgaa ttctgcaatt ttagctttga gagaagcatt
     2461 tatttcttga taagagccca ccagttcaac gagagacacg cattcgcgct gaatagacgc
     2521 aagctttgag ttcagctcac caatagccgc atttacttca gcttgagttt ttgcctcgtt
     2581 cattagtttt gcaatctggg ctgtttcacg aatagccgtc attgctgccg ttaattcagc
     2641 gatcacattg aatactctta ttgttgttgg ggatatccag attaaccgaa tccttgttgt
     2701 tggggaataa ccaggtccac ctcgcctgat gtggctaaaa gcaggcacat aacagctaag
     2761 tattttcaac cagagagaat ccttagcgtt gtggtgaatg cggctcagcg cacgcgggtt
     2821 aaggttgagg ctgacagtcg accttctgtg gatacccacc cgcctggtgt gcaaccttcg
     2881 ccaggcaccg ggaggcaccc ggcaccacaa ctttatgctg tgtgtagtcc tggcggtacc
     2941 agtttgtacc cttgcttccg gctggtaccg tccttttttg caaaacagag aagagcatca
     3001 ccggacgacg ggctcataac ccaatccatc cgggcggctg ccaccgcagg tgttcttctc
     3061 tgttttgtgg agaaaccaac cgaccttgca aggtcgatat gatgaggagc agcaaaatgg
     3121 ctagcgaacg cagtactgat gtgcaggcat ttatcgggga gctggacggc ggcgtatttg
     3181 aaaccaaaat cggcgcagtt ctcagtgagg tcgcttccgg tgtgatgaac acgaaaacca
     3241 aagggaaggt ctcactcaat ctggaaatcg aaccgtttga tgagaaccgt gtgaaaatca
     3301 aacacaaact ctcatatgtt cgcccaacta accgcgggaa aatttccgaa gaagacacca
     3361 ccgaaacgcc gatgtatgtc aatcgcggtg gtcgcctgac tattctgcag gaagaccagg
     3421 gacaattact gactcttgcc ggtgaacctg acggaaaact ccgcgcagca ggtcgttaat
     3481 atcgttcgta ataaactgat tatttatctc atcactgaat atctttatat agtgaggact
     3541 tattatgtct cagaacttag acgcaaccgc aattaatcaa atccatgccc ttatttctgc
     3601 tcagggtgtt aatgaaatta tcagtaagat tggtgccgat gctgtggcat tgcctgagaa
     3661 tttccgcatt catgatctgg aaaaatttaa tttaaatcgc ttccgtttcc gtggtgcact
     3721 ttccactgcc agcatcgatg attttacccg ttattctaaa gatcttgcag atgaaggcac
     3781 ccgctgcttt atcgatgccg ataatatgcg tgccgtcagt gtgcttaacc tgggtactat
     3841 tgatgagcca ggtcacgcag ataacactgc cactctcaaa ctgaaaaaga cagcaccgtt
     3901 ctctgctctg ttgtctgtta acggcgagcg taactcccag aagtcactgg cagaatggct
     3961 cgaagactgg gccgactacc ttgtgggctt tgatgctaat ggtgacgcca ttcaagcaac
     4021 aaaagcggct gcggcagtcc gtaaaatcac gattgaagca aaccagaccg ctgattttga
     4081 agataatgac ttcagcggca aacgctccct gatggagtct gtcgaagcga agaccaaaga
     4141 cattatgcca gtggcatttg aatttaaatg cgttccgttt gaaggtctga aagaacgtcc
     4201 gtttaaatta cgcctcagca ttatcactgg cgatcgtcct gtactggttc tgcgcattat
     4261 tcagctggaa gcggtgcagg aagaaatggc taacgaattt cgtgatctgc ttgttgagaa
     4321 attcaaagac agcaaagtag aaacctttat tggtactttc accgcctgat ttcattactg
     4381 caaatgcccc tgcgggggca tttatggaaa cgtaattaac tcaataatca ccggatggtg
     4441 agggcttcct tttaccagaa ttcagcgcgg tgcagtgcat atacgtggag aacaaaatgt
     4501 catttattaa aactttttcc gggaagcatt tttattatga caagataaat aaagacgaca
     4561 tcgatattaa cgatatcgcg gtttcccttt caaatatctg tcgctttgcc ggtcatcttt
     4621 cgcacttcta cagcgtcgcc caacatgcgg ttctttgcag ccagctggtg ccgcaggaat
     4681 ttgcttttga agcgttaatg catgatgcaa cagaagcgta ttgccaggac attcccgcac
     4741 cactgaaacg ccttattcct gactataaac ggatggaaga aaaaatagac gccgtaatcc
     4801 gtgagaaata cgggttaccc ccagttatga gtacacccgt gaaatatgcc gatctcatca
     4861 tgctggcaac cgaacgccgc gatctcgggc ttgatgatgg ctctttctgg cctgtactgg
     4921 aaggcatccc ggcaacagaa atgttcaacg tgattccact ggcaccgggt catgcctacg
     4981 ggatgtttat ggaacgtttt aacgatttat cggagttacg caaatgcgca tgaatgtttt
     5041 cgaaatggaa gggtttcttc gcgggaaatg tgtaccgcga gatctgaaag tgaacgaaac
     5101 aaatgctgag tacctgttac gtaaattcga cgcgcttgaa gctaaatgtg cggcactgga
     5161 aaacaaaata ataccagtgt cagctgaact gccaccagca aatgaaagtg ttctgttatt
     5221 tgatgctaat ggagaaggct ggctgattgg ctggcgttct ctctggtaca cctggggaca
     5281 aaaagaaacc ggagaatggc agtggacatt tcaggtcggg gaccttgaaa acgtcaatat
     5341 cactcactgg gcagtaatgc caaaagcacc ggaggctgga gcataatgac cacatttacc
     5401 aataaagaac tgattaaaga aatcaaagaa cgaatcagca
//
LOCUS       DAZUDJ010000155         5389 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.158, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000155 DAZUDJ010000000
VERSION     DAZUDJ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5389
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.158"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..487
                     /locus_tag="ACHY1N_004924"
     CDS             <1..487
                     /locus_tag="ACHY1N_004924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044384 - host outer membrane [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HFS4047072.1"
                     /translation="RTNVPGSDDLNGINVKYRYEFTDPLGLVTSFSYAGDKNRQLTRY
                     SDTRWHEDSVRNRWFSVMVGPSVRVNEWFSAYAMAGMAYSRVSTFSGDYLRVTDNKGK
                     THDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYK
                     F"
     gene            552..3467
                     /locus_tag="ACHY1N_004925"
     CDS             552..3467
                     /locus_tag="ACHY1N_004925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HFS4047073.1"
                     /translation="MAVKISGVLKDGTGKPVQNCTIQLKAKRNSTTVVVNTLASENPD
                     EAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYEDSQPGTLNDFLGAMTEDDARPEA
                     LRRFEQMVEEVARNASVVAQNTAAAKKSASDAGTSAREAATHATDAADSARAASTSAG
                     QAASSAQSASSSAGTASTKATEAEKSAAAAESSKSAAATSAAAAKTSETNAAASQQSA
                     ATSASTATTKASEAATSARDASASKEAAKSSETNASSSASSAASSATAAANSAKAAKT
                     SETNARSSETAAGQSASAAAGSKTAAASSASAASTSAGQASASATAAGKSAESAASSA
                     STATTKAGEATEQASAAARSASAAKTSETNAKASETSAESSKTAAASSASSAASSASS
                     ASASKDEATRQASAAKGSATTASTKATEAAGSATAAAQSKSTAESAATRAETAAKRAE
                     DIASAVALEDASTTKKGIVQLSSATNSTSESLAATPKAVKAAYELANGKYTAQDATTA
                     QKGIVQLSSATNSTSEMLAATPKSVKAAYDLANGKYTAQDATTAQKGIVQLSSATNSA
                     SETLAATPKAVKAANDNANGRVPSARKVNGKALSADITLTPKDIGTLNSTTMSFSGGA
                     GWFKLATVTMPQASSVVSITLIGGAGFNVGSPQQAGISELVLRAGNGNPKGITGALWQ
                     RTSTGFTNFAWVNTSGDTYDIYVAIGNYATGVNIQWDYTSNASVTIHTSPAYSANKPE
                     GLTDGTVYSLYTPSEQFYPPGAPIPWPSDTVPSGYALMQGQTFDKSAYPKLATAYPSG
                     VIPDMRGWTIKGKPASGRAVLSQEQDGIKSHTHSASASSTDLGTKTTSSFDYGTKSTN
                     NTGAHTHSVSGTAASAGNHTHSVTGASAVSQWSQNGSVHKVVSAASVNTSAAGAHTHS
                     VSGTAASAGAHAHTVGIGAHTHSVAIGSHGHTITVNAAGNAENTVKNIAFNYIVRLA"
     gene            3467..4042
                     /locus_tag="ACHY1N_004926"
     CDS             3467..4042
                     /locus_tag="ACHY1N_004926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0098004 - virus tail fiber assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HFS4047074.1"
                     /translation="MAFRMSEQPRTIKIYNLLAGTNEFIGEGDAYIPPHTGLPANSID
                     IAPPDIPAGFVAVFNSDEASWHLVEDHRGKTVYDVASGDALFISELGPLPENVTWLSP
                     GGEYQKWNGTAWVKDTEAEKLFRIREAEETKNSLMQVASEHIAPLQDAVDLEIATEEE
                     TLLLEAWKKYRVLLNRVDTSTAPDIEWPALP"
     gene            complement(4140..4730)
                     /locus_tag="ACHY1N_004927"
     CDS             complement(4140..4730)
                     /locus_tag="ACHY1N_004927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4047075.1"
                     /translation="MSRIYAYCRVSTLEQTTKNQRREIESAGFNIKSQQIIEEQISGS
                     AATSERPGFNQLLDRLKRGDALIVTKLDRLGCNPMDISKTVEQLTKAGIKVHCLALGG
                     VDLTSPPGKMMMQVISAVAEFERDLLLERTHSGILRARGAGKRFGRPPVLNDEQIQRV
                     LEQIKSGINISDIAQEFKTSRQTILRAKAKNQTPDI"
     gene            complement(5049..5282)
                     /gene="ydfK"
                     /locus_tag="ACHY1N_004928"
     CDS             complement(5049..5282)
                     /gene="ydfK"
                     /locus_tag="ACHY1N_004928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416062.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein YdfK"
                     /protein_id="HFS4047076.1"
                     /translation="MKSKDTLKWFPAQLPEVRIILGDAVVEVAKQGRPINTRTLLDYI
                     EGNIKKKSWLDNKELLQTAISVLKDNKNLNGKM"
BASE COUNT         1416 a         1281 c         1421 g         1271 t
ORIGIN      
        1 ccggacgaac gttcccggca gtgatgatct gaacgggatt aacgtgaaat accgttatga
       61 gtttacggac ccactggggc tggtgacgtc attcagctat gcaggagaca agaatcgcca
      121 gcttacccgt tacagcgata cccgctggca tgaagattcc gtgcgtaacc gctggttcag
      181 cgtgatggtg gggccgtctg tgcgcgtgaa tgaatggttc agcgcgtatg cgatggcggg
      241 tatggcttac agccgtgtgt cgactttctc cggggattat ctccgcgtaa ctgacaacaa
      301 ggggaaaacg cacgacgtgc tgaccggaag tgatgacggt cgccacagca acacgtctct
      361 ggcgtgggga gctggcgtgc agtttaaccc gaccgaatcc gtggccattg atattgctta
      421 tgaaggctcc ggcagtggcg actggcgcac tgacggtttc atcgtgggtg tcggttataa
      481 gttctgatta gccaggtaac acagtgttat gacagcccgc cggttcaggc gggctttttt
      541 gtggggtgaa tatggcagta aagatttcag gtgtactgaa agacggcaca ggaaaaccgg
      601 tacagaactg cacaatccag ctgaaagcaa aacgtaacag caccacggtg gtggtgaaca
      661 cgctggcctc agaaaatccg gatgaagccg ggcgttacag catggacgtt gagtacgggc
      721 agtacagcgt tattctgttg gtggaaggat tcccgccgtc acatgccggg accatcaccg
      781 tgtatgaaga ttctcaaccc ggtacgctga atgattttct cggtgccatg acggaggatg
      841 atgcccgtcc ggaggcactg cgccgttttg aacagatggt ggaagaggtg gcgcgtaacg
      901 cgtccgtggt ggcacagaac acggcagccg cgaagaagtc agccagtgat gccggcacat
      961 ctgcccgtga ggcggcaacc catgcgactg atgctgcaga ttcagcacgt gcagccagca
     1021 cgtcagccgg acaggccgct tcgtcggctc agtcagcgtc ttccagcgca ggaacggcat
     1081 caacaaaggc cactgaagcg gaaaaaagtg ctgccgctgc agagtcctca aaaagcgcgg
     1141 cagctaccag tgccgctgcc gcgaaaacgt cagaaacgaa tgctgcagcg tcacaacaat
     1201 cagccgccac ttctgcatcc accgcgacca cgaaagcgtc agaagctgcc acctcagccc
     1261 gggatgcgtc ggcttcaaaa gaggcggcaa aatcatcaga aacgaacgca tcctcgagcg
     1321 ccagtagcgc agcttcctcg gcaacggcgg cagcaaattc cgcgaaggcg gcaaaaacgt
     1381 ccgagacgaa cgccaggtct tctgagacgg cagcgggaca gagcgcctca gctgcggcag
     1441 gctcaaaaac agcggctgcg tcgtctgcca gtgccgcgtc aacaagtgcc gggcaggcct
     1501 cagccagtgc caccgctgcc ggaaaatcgg cagaaagcgc cgcatcgtcc gcttcaacag
     1561 ccacaacgaa ggctggcgaa gccactgaac aggccagcgc agcagcgagg tctgcttccg
     1621 cagcgaagac atccgagacg aacgcgaaag cgtcggaaac cagcgcagaa tcctcaaaaa
     1681 cggctgccgc atcgtccgcc agttcggcgg cgtcatcggc atcatctgcg tctgcttcaa
     1741 aagatgaggc gaccagacag gcgtcagcag caaagggcag cgccacgacg gcatccacga
     1801 aggcgacaga ggcagctggc agtgcgacgg cggcagctca gagcaaaagt acggcggaat
     1861 ccgcggcaac gcgcgccgag acagcggcaa aacgggcaga ggatattgca tccgccgtgg
     1921 cgcttgagga tgcgagcacg acgaaaaagg ggatagtaca gctcagcagt gcgactaaca
     1981 gcacttccga gtcactggcg gcaacgccaa aagccgttaa ggccgcgtat gagctggcta
     2041 acgggaaata caccgcacag gatgcaacga cagcacagaa agggatagtt cagctcagca
     2101 gcgcgaccaa cagcacatct gaaatgctgg cggcaacgcc aaagtcggta aaggcagcct
     2161 atgaccttgc taacgggaaa tatactgctc aggacgctac gacagcacaa aaaggaattg
     2221 tccagctcag tagtgcaacc aacagcgcat ctgaaacgct tgccgcgaca ccgaaagcag
     2281 tgaaagcagc taatgataat gcgaatggtc gggtaccttc tgcccgtaag gtgaatggta
     2341 aggcgctttc agcggatata acactgacgc cgaaagatat tggtacgctt aactcaacaa
     2401 caatgtcatt cagcggtggt gctggttggt tcaaattagc aacggtaacc atgccacagg
     2461 cgagttctgt tgtttcaatt acgttgattg gtggcgcggg atttaacgtg gggtcacctc
     2521 aacaggcagg tatatctgaa cttgttttgc gtgcaggtaa tggtaatccg aaggggatta
     2581 ctggtgcttt atggcagcgc acatcgacag ggtttacaaa ttttgcctgg gtcaatacat
     2641 ctggtgatac ttacgatatt tacgttgcaa tcggaaatta tgcgactggt gtaaatattc
     2701 aatgggatta taccagtaat gccagcgtga ctattcatac gtcaccagca tattctgcta
     2761 ataagccgga agggttaacg gacggtacag tttattcact ctatacacca tcagagcagt
     2821 tttatccgcc tggcgcacca atcccgtggc catcagatac cgttccgtct ggttatgccc
     2881 tgatgcaggg gcagactttt gacaaatccg cttacccgaa acttgcaacc gcttatccgt
     2941 caggcgtgat ccctgatatg cgtggctgga cgattaaggg caaacctgcc agtggtcggg
     3001 ccgtattgtc tcaggaacag gacggcatta aatcgcacac ccacagcgcc agtgcatcca
     3061 gtacggattt ggggacgaaa accacatcgt cgtttgatta cggcactaaa tccacgaata
     3121 acaccggggc gcatacgcac agtgtgagcg gtacagccgc aagtgccgga aaccatactc
     3181 atagtgtcac aggcgcatca gcagtcagcc agtggtcaca aaatgggtca gtacataagg
     3241 tagtgtctgc ggccagtgtg aatacaagtg ctgcaggagc gcacactcat agtgtcagcg
     3301 gcacagctgc atctgcaggt gctcacgcac atactgtcgg tattggtgct catacgcact
     3361 ctgttgcgat tggctcacat ggacacacca tcaccgttaa cgctgctggt aacgcggaaa
     3421 acactgtcaa aaacatcgca tttaactaca ttgtgaggct tgcataatgg cattcagaat
     3481 gagtgaacaa ccacggacca taaaaattta taatctgctg gcaggaacta atgaatttat
     3541 tggtgaaggt gacgcatata ttccgcctca tacaggtctg ccagcaaaca gtatcgatat
     3601 tgcaccgcca gatattccgg caggcttcgt ggctgttttc aacagtgatg aggcatcgtg
     3661 gcatctcgtt gaagatcatc ggggtaaaac ggtttatgac gtggcttccg gcgacgcgtt
     3721 atttatttct gaactcggtc cgttaccgga aaatgttacc tggttatcgc cgggagggga
     3781 atatcagaag tggaacggca cagcctgggt gaaggatacg gaagcagaaa aactgttccg
     3841 gatccgggag gcggaagaaa caaaaaacag cctgatgcag gtagccagtg agcatattgc
     3901 gccgcttcag gatgctgtgg atctggagat cgcaacggag gaagaaacct tgttgctgga
     3961 agcctggaaa aagtatcggg tgttgctgaa ccgtgttgat acatcaactg caccggatat
     4021 tgaatggcca gccctaccgt agggtaagat atataaattc tataattaga agtatctttc
     4081 catttaaggc taggaagggg ggcttggaaa acgtaaggaa tctcacaccg agattatttt
     4141 tatatatcag gtgtctgatt ttttgcttta gctcttaaaa tggtttgccg cgaggttttg
     4201 aattcttggg caatgtcact tatatttata cctgacttaa tttgctctag taccctctgt
     4261 atttgttcat catttaacac aggtgggcga ccaaatcgct ttcctgcgcc ccgtgctctt
     4321 aatatccctg aatgagtacg ctcaagtaaa aggtctcgct caaattcagc gactgctgaa
     4381 attacttgca tcatcatttt tccaggtgga ctggtcaggt caacgccccc caatgctaag
     4441 caatgcactt tgatacctgc tttggtcagt tgttccaccg ttttactgat atccattgga
     4501 ttacaaccga ggcgatccag ttttgtgaca atcaatgcat cacctctttt cagtcgatca
     4561 agcaactggt taaaaccagg acgctcactg gttgctgctg agccgctaat ttgttcttca
     4621 attatttgct gagatttgat gttaaaacct gcactttcga tttcccgacg ttgatttttg
     4681 gttgtctgtt ccagagttga tacccgacag taagcataaa ttcgagacat agtgagatct
     4741 tctatacgaa attggtgtac atatcataat gcatctcaga aaataatttt gattattttt
     4801 gtacatattt gtatgtacac gttcgaaaat aaacgaatgc gtatgcaacc ccgtaatttt
     4861 ggtgagaccc aaaatcgatt ttgtgaaaaa tggccttaac tcggtttgtt tttcgagttc
     4921 cgggcggact caaggaagaa gaatagtgtt gcgtgttatt ttaaccagat ttcaagttgt
     4981 ttggtcgtgg aaaagtggag caaaatgttg ttaaagtgga aaaatgataa aaaagtaagt
     5041 ttattatatt acattttacc atttaaattt ttgttgtctt taagaactga tatcgctgtt
     5101 tgtaataatt ctttgttatc cagccatgac tttttcttta tgtttccttc aatgtaatca
     5161 agcaatgttc tggtattgat aggtcttccc tgttttgcta cttccactac agcatcccct
     5221 aggataattc ttacttcagg aagctgcgca gggaaccact ttagggtgtc ttttgatttc
     5281 atgaagatat tccttaaaat attattgatt ttcattgcga tattgtatgt ctgattcagg
     5341 atatgttgac ttatacatcg gttttgtctg ggttattgga tatgccaat
//
LOCUS       DAZUDJ010000156         5372 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.159, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000156 DAZUDJ010000000
VERSION     DAZUDJ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5372
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.159"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            335..853
                     /locus_tag="ACHY1N_004929"
     CDS             335..853
                     /locus_tag="ACHY1N_004929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HFS4047077.1"
                     /translation="MPTPCYISITGQTQGNITAGAFTADSVGNIYVQGHEDEMLVQEF
                     LHNVTVPTDPQSGQPAGQRAHKPFIFTVALNKAVPLMYNALASGEMLPTTELHWWRTS
                     VEGKQEHYFTTRLTDSTIVDMKLHMPHCQDPAKREFTQLLEVSLAYRKIEWEHVKSGT
                     SGADDWRAPLEA"
     gene            1063..3204
                     /locus_tag="ACHY1N_004930"
     CDS             1063..3204
                     /locus_tag="ACHY1N_004930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HFS4047078.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFQQILDKMAYLTIWQGDDVQRRVKGMVTWFELGENDKNQMLYSMKVCPPLWRT
                     GLRQNFRIFQNEDIESILGTILQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAQKSTDQSLVLCDTVRYLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFDQEGQYQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MDGWRNNAEVARGTSRSPEIWPGRRIVLTGHPQANLNREWQVVASDLHGEQPQAVPGR
                     RGSGTTLDNHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKF
                     NWDRYNPSNQESSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTY
                     HQENRTPGSLPGTKTQMTIRSKTYKGSGFNELKFDDATGKEQVYIHAQKNMNTEVLNN
                     RTTDVINNHAEKIGNNQAITVTNNQIQNIGVNQIQTVGVNQVETVGSNQIIKVGSNQV
                     EKVGIIRALTVGVAYQTTVGGIMNTSVALLQSSQVGLHKSLMVGMGYSVNVGNNVTFS
                     VGKTMKENTGQTAVYSAGEHLELCCGKARLVLTKDGSIFLNGTHIHLEGESDVNGDAP
                     VINWNCGATQPVPDAPVPKDLPPGMPDMRQF"
     gene            3280..>5372
                     /locus_tag="ACHY1N_004931"
     CDS             3280..>5372
                     /locus_tag="ACHY1N_004931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6531 domain-containing protein"
                     /protein_id="HFS4047079.1"
                     /translation="MGGKPAARQGDMTRKGLDIVQGSAGVLIGAPTGVACSVCPNSPI
                     EEQKGNPVNPLLGAKVLPGETDLALPGPLPFILSRAYSSYRTRTPAPVGVFGPGWKAP
                     FDIRLQIRDEGLILNDSGGRSIHFEPLFPGEISYSRSESLWLARGGVAAQHSSQPLSA
                     LWQVLPEDVRLSPHVYLATNSLQGPWWILSWPERVPGADEVLPPEPPAYRVLTGVVDG
                     FGRTLAFHRAAEGDVAGAVTGVTDGAGRRFHLVLTTQAQRAEVFRKQRATSLSSPAGP
                     RSASSSLVFPDTLPAGTGYGTDNGIRLEAVWLTHDPAYPDEQPTAPLARYTYTAGGEL
                     RAVYDRSGTQVRGFTYDAEHAGRMVAHHYAGRPESCYRYDDTGRVTEQVNPEGLDYRF
                     EYGESRVIITDSLNRREVLYTEGEGGLKRVVKKEHADGSITRSEYDEAGRLKAQTDAA
                     GRRTEYSLHMASGAVTAVTGPDGRTVRYGYNSQRQVTSVTYPDGLRSSREYDERGRLT
                     AETSRSGETTRYSYDDPASELPTGIQDATGSTKQMAWSRYGQLLAFTDCSGYTTRYEY
                     DRYGQQIAVHREEGISTYSSYNPRGQLVSQKDAQGREIRYEYSAAGDLTATVSPDGKR
                     STIEYDKRGRPVSVTEGGLTRSMGYDAAGRITVLTNENGSQSTFRYDPVDRLTEQRGF
                     DGRTQRYHYDLTRKLT"
BASE COUNT         1264 a         1376 c         1684 g         1048 t
ORIGIN      
        1 tttaaggaat atctcaaaaa ttatcaaaat gataattcag aaaggataaa tacaatattt
       61 attcatgatt cagctttggc cattttatgg aggcaatacg gactttgaac agttgggtat
      121 ggttatccag atatatatta ttaagttatt gctgaataag agatttaatg attttaaaaa
      181 tagtttttac gacaaccgta aattctagct cggtttgtat gtaaaaaata ctgaaaaatg
      241 atgcggttcc gtgaagtgag ctgcatctgc ctgtctggga ttaacggcag gtcattgtaa
      301 gtagtaatta accacgttaa caaggagttt acaaatgcca acaccgtgtt atatctccat
      361 cactggtcag acccagggaa atattactgc aggtgcattt accgctgatt ctgtcggcaa
      421 catctatgtg caggggcacg aagacgagat gctggtgcag gaattcctgc ataacgttac
      481 tgtcccgacc gatcctcagt ccggtcagcc tgcgggtcag cgtgctcaca agcctttcat
      541 ttttaccgtg gcgctgaaca aagcggttcc gctgatgtac aacgcactgg cctccggcga
      601 aatgctgcca accactgaac ttcactggtg gcgtacctct gtggaaggca aacaggagca
      661 ttatttcact acccgcctga ctgattcgac gattgtcgat atgaaactgc atatgccgca
      721 ttgccaggac ccggcgaaac gcgagttcac ccagttgctc gaagtttcac tggcctaccg
      781 caaaattgaa tgggaacacg tcaaatctgg cacctccggt gccgacgact ggcgagcacc
      841 gctggaagca taagttaagc caacagcatc ctgctatcag gccggatgct gtttttgtat
      901 tacgccgtag aaagaaaggt tgtcagtaag gggttacgtt cacgggagat ggcggctgcc
      961 ggaaacttcg gcggtagcgt gcctgaacgc aagcgtaaca ctgtactgtc acagccgctt
     1021 taacagcgaa ctgtctgttt ttccttaacc ccggaggttg ctatgtcaac cggattacgt
     1081 ttcacgctgg aagtggacgg cctgccaccg gatgcttttg cggtggtctc ctttcatctg
     1141 aaccagtcac tctcttcgct tttttccctc gatctctctc tggtcagcca gcagtttctc
     1201 tcccttgaat tccagcagat cctcgacaaa atggcctacc tgacgatatg gcagggcgat
     1261 gacgtacagc gccgggtgaa aggtatggtg acctggtttg aactggggga gaacgacaaa
     1321 aaccagatgc tgtacagcat gaaggtgtgc ccaccgctgt ggcgcacagg gctgcgccag
     1381 aacttccgta tcttccagaa tgaggacatc gaaagcatcc tcggcacgat attgcaggaa
     1441 aacggggtga ccgagtggag cccgctgttc agcgagccac atccttcccg tgagttttgt
     1501 gtccagtacg gtgagactga ttacgatttc ctgtgccgga tggcggcgga ggaaggcatc
     1561 ttcttttatg aggagcacgc gcaaaaaagt accgaccaga gcctggtcct gtgcgatacc
     1621 gtgcgttatc tgccggagtc ctttgagatc ccctggaatc cgaacacccg taccgaggtg
     1681 agcaccctct gcatcagcca gtttcgctac agcgcacaaa tccgcccttc ttccgtggtg
     1741 accaaagact acacctttaa acgacccggc tgggcagggc gttttgatca ggaaggccag
     1801 taccaggatt accagcgcac acagtatgaa gtgtatgact accccggacg tttcaagggt
     1861 gcccacgggc agaactttgc ccgctggcag atggatggct ggcgcaacaa cgcagaagtg
     1921 gcgcgcggaa caagccgttc gccggagata tggccgggac ggcgaattgt gctgacgggg
     1981 catccgcagg cgaacctgaa ccgggaatgg caggtggtgg cgagcgatct tcacggcgaa
     2041 cagccgcagg cggtaccggg acgcaggggt tcaggcacca cgctggataa ccactttgcg
     2101 gtaatcccgg cagaccggac atggcggcca cagccgttgc tgaaaccgct ggtggacggc
     2161 ccgcagagcg ccgtcgtgac gggaccggca ggcgaggaaa tcttctgtga tgaacatggc
     2221 cgcgtgcggg tgaaatttaa ctgggaccgc tataacccgt caaaccagga aagttcatgc
     2281 tggatccgtg tggcacaggc gtgggcaggc accggctttg gtaacctggc gataccgcgt
     2341 gtgggtcagg aggtcattgt ggacttcctc aacggcgatc cggaccagcc gatcattatg
     2401 gggcgtacct accaccagga aaaccgcacc cccggcagcc tgccggggac gaagacgcag
     2461 atgacgatcc gctcgaaaac ctataagggc agcgggttta atgaactgaa gtttgacgat
     2521 gcgacaggga aagaacaggt ctacatccac gcgcagaaga acatgaacac cgaggtgctg
     2581 aataaccgca ccactgatgt gataaacaac catgccgaaa aaataggtaa caaccaggcg
     2641 atcaccgtta ccaataacca gatccagaac attggcgtta atcagataca gacggttggt
     2701 gtcaaccagg tggaaacggt gggcagtaac cagattatca aagtgggatc aaaccaggtt
     2761 gaaaaggtgg ggatcattcg tgcgctgacg gtgggtgtgg cttaccagac gacggtaggc
     2821 ggcattatga atacctcggt ggcgttgttg cagtcctcac aggtagggct gcataaatca
     2881 ctgatggtgg gaatgggcta cagcgtcaat gtggggaata acgtcacctt ctcggtgggc
     2941 aagacaatga aggaaaacac cggacaaaca gcagtttatt ctgccggtga gcatcttgaa
     3001 ctctgctgtg gtaaggcaag gctggtgctg acgaaggacg gaagcatatt tctcaatggt
     3061 acgcacattc atctggaagg ggagtcggat gtgaacggtg atgcgccagt gattaactgg
     3121 aactgtggtg ccacacaacc tgtaccggat gcgcctgtgc cgaaagattt accccccgga
     3181 atgccggata tgcggcaatt ttgagtcagg tgcaaaaaat taaaacggaa ctggtgcagt
     3241 gaccagataa accatattaa aagcagaagg aattgattca tgggcggaaa accggcggcg
     3301 cggcagggtg atatgacccg caagggactg gatattgtgc agggttcagc gggggtgctg
     3361 ataggtgcgc cgacgggagt ggcctgttcg gtatgtccca acagcccgat agaggagcag
     3421 aagggtaacc cggtgaaccc gctgctggga gcaaaggtgc tgccgggcga gacggacctt
     3481 gcgctgcccg gcccgctgcc gtttattctt tcccgcgcct acagcagcta ccggaccaga
     3541 acacccgcgc cggtgggggt gtttggtccc ggctggaaag cgcccttcga tatccgctta
     3601 cagatacgcg atgaaggcct gatactcaac gacagcggcg gcaggagcat tcactttgag
     3661 ccgctgtttc ccggcgagat aagctacagc cgcagcgagt cactctggct ggcgcggggc
     3721 ggagtagcgg cgcagcacag ttcgcagccg ctaagcgcgc tctggcaggt gctgccggaa
     3781 gatgttcgcc tgagtccgca tgtgtacctg gcgacaaaca gccttcaggg gccgtggtgg
     3841 atactcagct ggccggagcg ggtgccgggg gcggacgagg tgctgccgcc ggagccgccc
     3901 gcataccggg tgctgacggg cgtggtggac ggcttcgggc ggacgctggc ctttcaccgg
     3961 gcggcggagg gtgatgtggc gggcgcggtg acgggggtga cggacggcgc gggccgccgt
     4021 tttcacctgg tgctgaccac acaggcacag cgggcggaag tattccgtaa acagcgcgcc
     4081 acgtctttat cttcccctgc cggtccccgt tctgcttcct cttctctggt tttccccgac
     4141 acgctgcccg ccggtacagg atacggcacg gataacggta tccggctgga ggcggtatgg
     4201 ctgacacacg acccggcata cccggatgaa cagccgactg cgccgctggc gcgctacacg
     4261 tacacggccg gtggtgaact gcgggcggtg tatgaccgca gcggaacgca ggtgcgcggg
     4321 tttacttatg atgcggagca cgccgggcgg atggtggcgc accattatgc ggggaggccg
     4381 gagagctgct accggtatga tgataccggt cgggtgacgg agcaggtcaa cccggagggg
     4441 ctggactacc gctttgagta cggagagagc cgggtaatca tcacggacag cctgaaccgg
     4501 cgggaggtgc tgtacacgga aggcgagggt ggcctgaagc gggtggtgaa gaaggaacat
     4561 gcggacggga gcattacccg cagcgagtat gatgaggcgg ggaggctgaa ggcacagacg
     4621 gatgcggcgg ggcggcggac ggagtacagc ctgcatatgg cgtcgggtgc ggtgacggcg
     4681 gtgacggggc cggacggcag gacggtgcgg tatggctata acagccagcg gcaggtgacg
     4741 tcagtgacgt acccggacgg gcttcgcagc agccgggagt atgatgagag gggaaggctg
     4801 acggcggaga cctcgcgcag cggtgagaca acgcggtaca gctatgatga cccggcgagt
     4861 gagctgccga cagggataca ggacgcgacg ggcagtacaa aacagatggc atggagccgt
     4921 tacggtcaac tgctggcctt cacggactgc tcggggtaca cgacgcggta tgagtacgac
     4981 cggtacggtc aacaaatcgc cgttcaccgg gaggaaggca tcagcactta cagcagttat
     5041 aacccgcgtg ggcaactggt cagtcagaag gatgcgcagg ggcgtgaaat ccgttatgag
     5101 tacagcgccg caggcgacct gacagcaacg gtatcaccgg acggtaaacg cagcaccatc
     5161 gaatatgata aacgcgggcg tccggtgagt gtgacggaag gcggtctgac gcgcagcatg
     5221 gggtatgacg ctgccgggcg catcactgtg ctgaccaacg agaacggcag ccagtccacg
     5281 ttccggtatg acccggtcga caggctgact gaacagcgcg gttttgacgg ccggacgcaa
     5341 cgttaccact atgacctgac cagaaaactc ac
//
LOCUS       DAZUDJ010000157         5304 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.160, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000157 DAZUDJ010000000
VERSION     DAZUDJ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5304
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.160"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..174)
                     /locus_tag="ACHY1N_004932"
     CDS             complement(<1..174)
                     /locus_tag="ACHY1N_004932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ESPR domain-containing protein"
                     /protein_id="HFS4047080.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAA
                     VMSVPALAADIVVR"
     gene            complement(502..1374)
                     /locus_tag="ACHY1N_004933"
     CDS             complement(502..1374)
                     /locus_tag="ACHY1N_004933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HFS4047081.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTRHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVRSFRLSGHGHSMVITDLPGVGESRDRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQRVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRSQAREQFTGAVDRIFDTAESVCVASVVRTALRAVRDT
                     VVSVARAVWNWIFF"
     gene            2606..4090
                     /locus_tag="ACHY1N_004934"
     CDS             2606..4090
                     /locus_tag="ACHY1N_004934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfjI family protein"
                     /protein_id="HFS4047082.1"
                     /translation="MSFGQPCDEFPLSSLPPLIRDAVIEAQQITQAPLGLVAASALGA
                     VSLVCQNLIDVCRLNTLRGPVSLFFLTLAESGERKTAVDKLLMKPLYQQEMQLYSRYK
                     SELAVWKNKEELLKAQKKALLSKLNKELRKGADESETLRQLEVLQKNSAEEPVRYKFI
                     FNDATTAAIKNQLCGKWRSVGIMSDEAGIIFDGYTLSELPFINKMWDGSVLSVDRKNE
                     PEQMIENARMTLSLMVQPGLFDRYMERKGSVARDSGFLARCLISKPATTQGKRFINGA
                     VIPGGSLTAFHERLMELARGSIEKSSEDERYCLHFSPEAQKIFIEHYNVLEQDLSPSG
                     PLSPFRGHVSKKTENIARIAALFQYFSYGEGKISADIMTSAVVISSWYTDEYKKLFAL
                     PDESELQQKDAEELFDWLIEECRGECPPRVRKNYILQCGPGRFRNRKKLNALLNILES
                     QFRLSVVPEGKTMYVLLPQIASLKLSDVSGIFTSGYHYNKLRAK"
     gene            complement(4412..5014)
                     /locus_tag="ACHY1N_004935"
     CDS             complement(4412..5014)
                     /locus_tag="ACHY1N_004935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001590672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047083.1"
                     /translation="MKPQYQTRYELLHESYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRTTPPLDDDLIVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNCLDDWTENLKRK
                     SEKELEEWIINRQKQSAALTDLMDQYVLLAYRTTVDDKRT"
     gene            complement(5101..5304)
                     /locus_tag="ACHY1N_004936"
     CDS             complement(5101..5304)
                     /locus_tag="ACHY1N_004936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4047084.1"
                     /translation="MTPVSLMDDQMVDMAFITQLTGLTDKWFYKLIKDGDFPAPIKMG
                     RSSRWLKSEVEAWLQARIAQSRP"
BASE COUNT         1338 a         1174 c         1361 g         1431 t
ORIGIN      
        1 gcgtacaacg atgtcagcag ccagtgccgg gactgacatg acagcagcaa gagacagagc
       61 aaccgccaca ccggcgcgtt ttccccgtga gcgggccagt tcggaagcca ccaccagggt
      121 gcccgtaatg tgattccata ccagcctgta gctggtgttc agatgtcgtt tcatcagctt
      181 ttccttagat tgagggtgaa taaaaaagcc ggtacccaca aacgtggata ccggcaggta
      241 aagggttaca gtgccggagg tccggctgtg ggagtttctg aattgtggtt ctgttgttcc
      301 ctgaatgtct ttctgtacgt atctgtgcat gttactgaca aaggttatta ttagcttatc
      361 gatcgatata aacgatcgat aaaacagata tcgatcgttt tattctatta ttgagctatt
      421 gcacggacaa gagagacagt aacgaaaaca gtgcttttgt gagcagactc agagtcaggg
      481 agggcatcag tcacgacagg ttcagaagaa aatccagttc cataccgcac gggcaacaga
      541 gaccaccgtg tcacgaacag cgcgcagggc cgtacggaca acagaggcaa cacagacgct
      601 ctccgctgtg tcaaatatcc ggtccaccgc accggtaaac tgttcacggg cctgagagcg
      661 gacagattcc gtgcgcagct cgtcctgcag tcgggtcatc aggggactgg cggcatggtc
      721 gggaagcgct gtcatgagcg cactgaccag cgtatccagt tcccagccgg tgcgggccga
      781 tacggccaca accggatgta cgggccggaa cagacggaat accgcctccg ttttttcgcg
      841 aatattctgt gcctgtgcag gagaaggctg aataccggcc atatcccatt catggcaggg
      901 ctccgttttg tcggcctgcg tcaccacaaa cagtacccgc tgatgtcccc ggtgcaggat
      961 gtgtcgccag aaatactcat ccacagacag ggcacggtca tcggctttaa tcagccacag
     1021 taccaggtcc agttcaggca gaatgtcacg gtacagggcc tcatactctg catccctgtc
     1081 ccggctctcg cccaccccgg gcaggtcagt gataaccatg ctgtgaccgt ggccactcag
     1141 acggaagctc cgtacttccc gggtgccggc gtgaacatca ctgaccgggg tgacctcccc
     1201 ctgaaacagt gcattacaga gtgaggattt accggccccg cttttaccca taatgccaat
     1261 cacgggttcg tgacgggtga gtttgcgcag atgttccagg atgtgacggg aaagcgagta
     1321 aggcagggag gagagcggtt tttcaattgc ctcaatggca tcagacggat tcatacatgt
     1381 attcccggtg aaaaaagaca aaaccccgcg caccggaaag gtggcggggg attcacggag
     1441 ataatatctg tctgaaattg ttttgaatcg atgggattgt tgcgtattaa catgaaggag
     1501 atcaggactt atccgttact gggtgatctc cttccatgaa aatacgccgt tattgttaaa
     1561 cagcaggctg atttctccgt aaaggggaaa atatttatcg gctgtatgat tatcaggtgt
     1621 gtctgtgttt actgctgtga gtatttttta gtgtattgtg ggggagatgt cagtgggaga
     1681 tattaaattt acgtttataa ttatcttact tcttctgtgt gttttttata agagtgcaca
     1741 cgtaatgata tctgttgata ccatgtggtt aagtgtttcc cttcctggtc atgcgtaatg
     1801 attaaatgct tttgtgacac cattcttccg gtctgaatat ttatcccgtt cttttttatt
     1861 tgtgcagtga tactgtcgga agagaattca gtaatgtgag gtgtcctggt caggataata
     1921 tctgctgaga tattattagt tgagtgtgtt tttactgagc aaaagctggc ttttaattcc
     1981 tgtactgaaa cactgtcgct cgtccggggt taactgaaac tggatgatga tgtaaaatga
     2041 aggctgtttt tgtgtttgtc gaagaagtgt tattttaatc cattctcatc attggctggc
     2101 gattatacag aagtatttga agaaaaaatg gtgcatttta tctgtgtcag cagggaagaa
     2161 gtattttatt gatgtatcag tattaaatgg tttttgttat ttataaaaat gtcatcctgt
     2221 ccatagaata ttgtactcag cattcagtgc aggaactgta gtcttcttta ttttattctt
     2281 cttcaggagg gggggtgatt cctgaaggcg ttattcccgg tgttctgttt atgattcttc
     2341 ccggcaggaa accggtatct gcaatacccg ggatgatgct ttttgttcgt acgtggttgt
     2401 gtaaaatttg aatagtggat gtgctccgaa gggaaggagg ggacacacag attcattttg
     2461 tctttcttca gcagcaaaat acactgtggt tattatttaa ccattaaatc aacaaaaatt
     2521 tttacctcat attgatttga gtgctatttt tgctattaat agccagaatt gcagtgcttt
     2581 tatatctgtg tatagtgagg ttactatgtc attcggtcag ccttgtgatg agtttcccct
     2641 gagttcgctg cctccactca ttcgtgatgc cgttattgaa gctcagcaaa ttacgcaggc
     2701 tccccttggg cttgtggcag cgtctgccct gggcgctgtt tcacttgtct gccagaatct
     2761 gattgatgtc tgcagactga atacactgcg ggggccggtc tctctttttt tcctgacgct
     2821 tgccgagtcc ggagaacgaa aaaccgcagt ggacaaatta ttaatgaagc ccctgtacca
     2881 gcaggagatg cagttatatt ccagatacaa aagtgaactg gctgtctgga aaaacaagga
     2941 agagctttta aaggctcaga aaaaagcatt gttgtcaaaa ctgaataaag aactccgcaa
     3001 aggcgcggat gagtcagaaa ccctcagaca actggaagta cttcagaaaa acagtgcgga
     3061 agaacctgtg aggtataaat tcatttttaa tgatgccacg actgcggcaa ttaagaatca
     3121 gctttgtggt aaatggcgtt cagtgggtat tatgtcagat gaagccggta ttatatttga
     3181 tggatatacc ctgtctgagt tgccttttat taacaaaatg tgggatggct ctgtattgtc
     3241 tgtggacaga aagaatgaac ccgaacagat gattgaaaat gccagaatga cgttatccct
     3301 catggtgcaa cccggtcttt ttgaccgata tatggagcga aaaggttctg ttgccaggga
     3361 cagtggtttt cttgcccgtt gtcttatcag taaacctgca accacgcagg ggaaacgctt
     3421 tattaacgga gctgtgattc cgggaggatc attaacggca tttcatgaac gattaatgga
     3481 actggccaga ggcagtattg aaaaatccag tgaggatgaa cggtattgtc tgcatttttc
     3541 gcctgaagcg caaaaaatat ttattgagca ctataatgtt ctggagcagg atttatcccc
     3601 ttccggaccc ttaagcccgt ttcggggaca tgtttcaaaa aaaacagaaa acattgcaag
     3661 aattgcagcg ttatttcagt atttcagcta tggtgaaggg aaaatctctg ccgatatcat
     3721 gacgtctgct gtcgtaataa gttcgtggta cacagatgaa tataaaaaat tatttgcgtt
     3781 acctgatgaa tctgaactgc agcagaagga cgccgaggag ctgttcgact ggctcattga
     3841 ggagtgccgc ggagaatgcc cgccccgtgt caggaaaaat tatattctcc agtgtggccc
     3901 gggccggttc agaaacagga aaaaactgaa cgcattgctg aacattcttg aatctcagtt
     3961 caggctttct gtcgtgccgg aaggaaaaac catgtatgtt ctgcttcccc agatagccag
     4021 tttaaagttg tctgatgtct ctggtatttt tacctcgggt tatcactaca ataagctgag
     4081 agcgaagtaa ccggtgagca gtttttctcc attatgcttc agacttagat gattgattat
     4141 tatggggatt tcatcaccga tattcagatg tatgaatatc ggtgatgaac taaagctcag
     4201 gagctgcgtg gtggtgatga atcaacaggc atataactga tacccgccgg tcagaagttc
     4261 cagcctgcga ctttcctgtc tgcgtgcccg cagtccggcg ttcaggtgca gcgtgtgaca
     4321 gaacgcacgg agagcgaaac ggcaggcaga caggccgttc agtcagccct ggcaccctgc
     4381 ccggatacca gcttccctga aacaactggc atcaggtgcg cttatcgtca accgttgtgc
     4441 ggtatgccag gagcacgtac tgatccatca gatccgtcag tgctgcgctc tgcttctgac
     4501 ggttgatgat ccattcctcc agctcttttt ctgatttccg tttcagattc tccgtccagt
     4561 cgtcaaggca gtttccggtc attaaatcaa gccagcaaag ccagaccagt ttgaggcgca
     4621 actccgtgcc accaaactga cggaagaggc tgatcagttt atttgccagc gaacgctgcc
     4681 tcagacgttc acattcagac aggagaatgc cttccagcat cggatgatga accagcagat
     4741 gttcactggt gcataaattc actatcagat catcatccag gggcggcgtg gtccgtttgt
     4801 ccggaccata aatcagccgg tgcagactct ggggtacgat ggcaatctcc ggtttttcac
     4861 cattgaatga cacccacccg ggcgtcagat tatggaagta gtagatattc ggatgacaca
     4921 cgccccagga tacggcgtgc cgggtgaagc cggtcagcca tttctggtag ctttcgtgga
     4981 gcagctcgta acgggtctga tactgtggtt tcattttcat attcctcacg ggggataaca
     5041 ggcagcagaa cgccgccggc aggccggaga ctgcgtctgc tgcagatgaa cggttaagaa
     5101 ttacggacgg gactgtgcaa tacgcgcctg cagccaggct tccacttcgc ttttcagcca
     5161 tcgggagctg cggcccattt tgatgggcgc aggaaagtca ccatccttga tgagtttgta
     5221 aaaccactta tcggtcaggc cggtcagttg agtgataaat gccatgtcga ccatctggtc
     5281 atccatcagt gaaactgggg tgat
//
LOCUS       DAZUDJ010000158         5216 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.161, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000158 DAZUDJ010000000
VERSION     DAZUDJ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5216
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.161"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..313)
                     /gene="gadE"
                     /locus_tag="ACHY1N_004937"
     CDS             complement(<1..313)
                     /gene="gadE"
                     /locus_tag="ACHY1N_004937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadE"
                     /protein_id="HFS4047085.1"
                     /translation="MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVI
                     IDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEIT
                     YG"
     gene            complement(1112..1684)
                     /gene="hdeD"
                     /locus_tag="ACHY1N_004938"
     CDS             complement(1112..1684)
                     /gene="hdeD"
                     /locus_tag="ACHY1N_004938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-resistance protein HdeD"
                     /protein_id="HFS4047086.1"
                     /translation="MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFV
                     SGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPEL
                     GIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVS
                     VTLVSTLVGIELIFSAASLFSFASLFVKQQ"
     gene            1939..2271
                     /gene="hdeA"
                     /locus_tag="ACHY1N_004939"
     CDS             1939..2271
                     /gene="hdeA"
                     /locus_tag="ACHY1N_004939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeA"
                     /protein_id="HFS4047087.1"
                     /translation="MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLA
                     VDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKQANFKDKVKGE
                     WDKIKKDM"
     gene            2387..2713
                     /gene="hdeB"
                     /locus_tag="ACHY1N_004940"
     CDS             2387..2713
                     /gene="hdeB"
                     /locus_tag="ACHY1N_004940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417966.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HFS4047088.1"
                     /translation="MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFID
                     LNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQA
                     SNDLPN"
     gene            2777..3424
                     /gene="yhiD"
                     /locus_tag="ACHY1N_004941"
     CDS             2777..3424
                     /gene="yhiD"
                     /locus_tag="ACHY1N_004941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFS4047089.1"
                     /translation="MTAEFIIRLILAAIACGAIGMERQMRGKGAGLRTHVLIGMGSAL
                     FMIVSKYGFADVLSLDHVGLDPSRIAAQVVTGVGFIGAGNILVRNQNIVGLTTAADIW
                     VTAAIGMVIGSGMYELGIYGSVMTLLVLEVFHQLTFRLMNKNYHLQLTLVNGNTVSML
                     DWFKQQKIKTDLVSLQENEDHEVVAIDIQLHATTSIEDLLRLLKGMAGVKGVSIS"
     gene            complement(3466..3996)
                     /gene="dctR"
                     /locus_tag="ACHY1N_004942"
     CDS             complement(3466..3996)
                     /gene="dctR"
                     /locus_tag="ACHY1N_004942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="HFS4047090.1"
                     /translation="MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVI
                     IDTLMNNVFHSNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTITIIDFVALI
                     NGSYCSVPEAAVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNL
                     KRINELVRHQHIDYLV"
     gene            complement(4152..4718)
                     /gene="slp"
                     /locus_tag="ACHY1N_004943"
     CDS             complement(4152..4718)
                     /gene="slp"
                     /locus_tag="ACHY1N_004943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312404.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein Slp"
                     /protein_id="HFS4047091.1"
                     /translation="MNMTKGALILSLSFLLAACSSIPQNIKGNNQPDIQKSFVAVHNQ
                     PGLYVGQQARFGGKVINVINGKTDTLLEIAVLPLDSYAKPDIEANYQGRLLARQSGFL
                     DPVNYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYG
                     YGAFWPEPGWGAPYYTNAVSQVTPELVK"
     gene            complement(5072..5216)
                     /locus_tag="ACHY1N_004944"
                     /pseudo
     CDS             complement(5072..5216)
                     /locus_tag="ACHY1N_004944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312403.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1591 a         1041 c         1046 g         1538 t
ORIGIN      
        1 taccataagt aatctcaaga agatttttga tactttcttt gcggctaaca aaataaatag
       61 gcgctttagc ttttagttta ctgatgtgat aaggtgccaa aacaataatt ctctcggcat
      121 ctaatttctc cagaaattta atcgcttctt catcaaggat atgattgtga taggtatcaa
      181 tgataacctt gaagggttta ttgcctactt ttttgatctc tgacagggaa ttgattttta
      241 tcatttcgtg attatctttc aactgccaaa agccctgtaa aagaaaagaa tctttcgtca
      301 tgagaaaaat cataacttgc tccttagccg ttatcgtttc gaacatgtca tccttttcat
      361 tatttacatc cttgtccgaa tcgttgttca atatagtaaa cgcctataag aactttgccc
      421 ttcgtgaact aatacgtcta ttaacactaa tcaatacttc agatttatcc atcacgcact
      481 ccatatattg atcctaagta agattcctgg ctgttatcaa tttgtaaata tcaaacaaaa
      541 agttaacgtt tgcggattac tgcccaagaa taagttatca ataaccagtt tgtgatctct
      601 gaagaatatt actaaagtta aaatgtaatc cgatttaaat atcgagtctc cttgtttcga
      661 cttaagctgg caattggatt gccagctttc ttttaacgca ttgaaattac ctgagtaaat
      721 aacgcattca tgtcttcagg tttttatata gcgtctggag acacggatat ttatgcaatg
      781 taatcaacgc cagttgcaaa aaaatgaacc cggattactt atttaaccgc ccatagcatc
      841 aacgcttacg gaactctttg ttcactttcc cacagcactt ttaaaacatt aaacctgact
      901 acggaaaata tcagccatga taatgtttga aatggctaat ttgccatgga gtgaaaaaaa
      961 ttagatgaaa ttcagtaggt tgaaatgatc actagcaggt aattatttca atgatagtgc
     1021 gcaattgatc tacaacactg cgtagcggag agagtattaa tcggatcata gtcacatcaa
     1081 gtgactatga tccgggtgac aaccgggata attattgctg cttaacgaac aaactggcga
     1141 agctgaacag gctggcggcg ctaaatatca gttcaattcc caccagtgtg gaaaccagcg
     1201 ttacagacac catcggcgtt gcaccaagga atatccaggc aatgacgata tccagcacac
     1261 caataacgag ctgtagccag ctgcctttca ttgaacgctg acgataccaa ctcatcaggc
     1321 gaataacccc tgcaacacag aacaaaccgg caataaatgc cgcaatggca aaaatgccca
     1381 gctccggtgc gcggatgaag aaatagccga tcaataaata ggcgactgcg acgaggaaac
     1441 cggataatac cggccagaaa ttatgactgc ggttgctgaa taacccgaca ataagcgcaa
     1501 tacccgagca gattaataat gcacccacta ctgtgcttaa aatatcgcca gagacgaacg
     1561 ggaaactgat acacagcaac ccgacgataa acagcagcac ggcaataaac tggattgctc
     1621 tgcgatgctt tttcagcatc tccagatcaa acttcaaaat tgttgcctta tctatatata
     1681 acatagaacc accctataaa attaagaaga aaatcccctg ctatcaatct atgccaaaaa
     1741 cgcgtctaag aatgcagtcg atttaataaa aatttcctaa ttgcagtatc tgatgcatct
     1801 gtaactcatt gtattgaaat aaaaatatct gattttgata ttttccatca acatgacata
     1861 tacagaaaac caggttataa cctcagtgtc gaaattgatt cgtgacggct ctttcacttt
     1921 atagttgagg atattacgat gaaaaaagta ttaggcgtta ttcttggtgg tctgcttctt
     1981 ctgccagttg tgagcaatgc agcggatgcg caaaaagcag ctgataacaa aaaaccggtc
     2041 aactcctgga cctgtgaaga tttcctggct gtggacgaat ccttccagcc aactgcagtt
     2101 ggttttgctg aagcgctgaa caacaaagat aaaccagaag atgcggtttt agatgttcag
     2161 ggtattgcaa ccgtaacccc agctatcgtt caggcttgta ctcaggataa acaagccaac
     2221 tttaaagata aagttaaagg cgaatgggac aaaattaaga aagatatgta attccgggaa
     2281 tgcgttacat cgtacttcct tgcatattga acaggccgga atatcttctt taaaagcagc
     2341 tattcctcct gttcatatat aatctctata ttgaatgggt tacaaaatga atatttcatc
     2401 tctccgtaaa gcgtttattt ttatgggcgc tgtagcggct ttgtcactgg tgaacgcaca
     2461 atctgcgctg gcagccaatg aatccgctaa agatatgacc tgccaggaat ttattgatct
     2521 gaatccaaaa gcaatgaccc cggttgcatg gtggatgctg catgaagaaa cagtatataa
     2581 aggtggcgat accgttactt taaatgaaac cgatctcact caaattccta aagtgatcga
     2641 atactgtaag aaaaacccgc agaaaaattt gtataccttc aaaaatcaag catctaatga
     2701 cttgccgaat taatgaggta caagtaaaaa ggagtagcaa gttgagccat cttgctgctc
     2761 ctttttgcat ttttatatga cagcagaatt tattatacgt cttatactcg cggcaattgc
     2821 ctgtggcgct attggcatgg aaaggcaaat gcgcggcaaa ggagcagggt tacgcacaca
     2881 tgtattaatt ggcatgggaa gcgccctgtt tatgattgtt tcgaaatatg gttttgctga
     2941 cgtgctgtct ttagatcacg tcggactcga ccccagccgt attgctgctc aggtggtgac
     3001 gggcgtcggg tttatcggtg caggtaacat tctcgttcgt aaccaaaata ttgtaggtct
     3061 gacgacggca gcggatatct gggtgaccgc cgccataggt atggttattg gcagcggtat
     3121 gtacgaactg ggtatttatg gttcagtgat gaccttgttg gtgctggaag tcttccatca
     3181 attaaccttc cgcctgatga acaaaaatta ccatttacag ctgacattag tgaacggtaa
     3241 tacggtatca atgctcgact ggtttaagca gcaaaaaata aaaacggatt tagtttcgtt
     3301 gcaggaaaat gaagatcatg aagtggtcgc cattgatatc cagcttcatg ccacaacgtc
     3361 gatagaagac ctgttgcgat tattaaaagg tatggcaggg gtgaaaggcg tttcaattag
     3421 ctaatctgtg tggcagcgta gccagactca ccgtaagcct gaaattcaca ccagataatc
     3481 aatatgctga tggcgtacca gctcattgat ccgcttaaga ttgaggatca tcatgatatt
     3541 gtgtttatgg cagtagaacg tttttagcga tattttcagt ttctccagaa tatcttccgt
     3601 tgtcatttga ttcgcaatgc agctcagaac ctgatgttgc ttgcgcgaaa gtgacacagc
     3661 cgcttcaggc acagagcagt aactgccatt gatgagtgcg acaaaatcaa tgatagtgat
     3721 agtccgcgga acaaaggtca ccggcacttt ccccaggcag cgtttaatat taaaggggga
     3781 gaaaataatc acatggacag gttttaatcg ttcaatttga gtgagaaaat tagaatgaaa
     3841 tacattattc attaatgtat caataatgac gaaggcattc tgatgcaaca ttacgtcgat
     3901 ctcttcttcg ttctgtatat gaacgacatt acctttactc agaatgtttt tcatcgcggt
     3961 gaagaacatc gtatccctgg taattataag aaacataacc gactcctggt gcggacatta
     4021 actttataat cagtttgcca aaggtaatta acaggacagg gcttataata ataatagtta
     4081 gcttactgta tattaatttt atgtaataca tgatgcagat gctgagaaag catctgcatc
     4141 tttcggtggt gttatttgac cagctcaggt gttacctgac tcaccgcatt ggtgtagtaa
     4201 ggcgcacccc agcccggttc cggccagaat gcaccatagc cgtaatccca caggttatag
     4261 gtggtattaa ccacttctct caaatgccac acctggatgc cctgcatatt cacttccagg
     4321 aagttatacg ggactttatt gataaagcct ggttgttcac cctgaatggt accgaggatg
     4381 gtaacaaagt gattacgata gttcactgga tcaaggaagc cgctttgtct ggcgagcagt
     4441 cggccctgat agttggcttc aatatcaggc ttcgcatagc tatccaacgg taatacagcg
     4501 atttctaaca acgtatccgt tttgccattg ataacgttga taaccttccc accaaagcgc
     4561 gcttgttgac caacatataa ccccggctgg ttatgaacag caacaaaact tttttgaata
     4621 tcaggttggt tattgccttt gatattttgc ggaattgaac tacatgcggc aagcaaaaat
     4681 gaaaggctga ggatgagtgc accttttgtc atgttcatgt tactatcctt atcaacaaat
     4741 attaaaacca taatagatat ttctttatag ttttcatctg attctgaggt gatatgcctg
     4801 atagtaacgt aaacctgtct gatgtttata tcccttctgt ttagttcaat tccgttattt
     4861 tggggcgtgg tatgagtatc catcgcccaa taatataacc ctttgtttta aaattacata
     4921 aaatctattt ttattcaata attataaagt gctaataatc aatattatgg tattatattc
     4981 tgataatgat ttgataagcg aattcttttg ccagatggta tttctatttc caccccataa
     5041 tttatatctt tttcattagg aagtggcctc tttaaataag gcgtgtgtga catttttttg
     5101 gggttaagcg tctcgtattg aaatacttcg aactgatatt cagacatttc tgcccatgtt
     5161 tgaattttat tgtatcgaga gagtgtcgca aaggctttaa cttgcttata acattg
//
LOCUS       DAZUDJ010000159         5157 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.162, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000159 DAZUDJ010000000
VERSION     DAZUDJ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5157
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.162"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..911
                     /locus_tag="ACHY1N_004945"
     CDS             <1..911
                     /locus_tag="ACHY1N_004945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415162.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="YbeF family transcriptional regulator"
                     /protein_id="HFS4047092.1"
                     /translation="SEGKPQIFTTLRNIDLNLLTIFEAVYVHKGIVNAAKVLNLTPSA
                     ISQSIQKLRVIFPDPLFIRKGQGVTPTAFAMHLHEYISQGLESILGALDIEGSYDKQR
                     TITIATTPSVGALVLPVIYRAIKTHYPQLLLRNPPISDAENQLSQFQTDLIIDNMFCT
                     NRTVQHHVLFTDNMVLICREGNPLLSLEDDRETIDNAAHVLLLPEEQNFSGLRQRVQE
                     MFPDRQINLTSYNILTIAALVANSDMLAIIPSRFYNLFSRCWPLEKLPFPSLNEEQID
                     FSIHYNKFSLRDPILHGVIDVIRNAF"
     gene            1120..2085
                     /gene="lipA"
                     /locus_tag="ACHY1N_004946"
     CDS             1120..2085
                     /gene="lipA"
                     /locus_tag="ACHY1N_004946"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016992 - lipoate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HFS4047093.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKS
                     PQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(2186..2389)
                     /gene="tatE"
                     /locus_tag="ACHY1N_004947"
     CDS             complement(2186..2389)
                     /gene="tatE"
                     /locus_tag="ACHY1N_004947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HFS4047094.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMN
                     DDDAAAKKGADVDLQAEKLSHKE"
     gene            complement(2518..3306)
                     /locus_tag="ACHY1N_004948"
     CDS             complement(2518..3306)
                     /locus_tag="ACHY1N_004948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
                     /protein_id="HFS4047095.1"
                     /translation="MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLA
                     RDDHDADLSVKSAQLLEGELLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG
                     NIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
                     LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPF
                     GVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL"
     gene            3399..3782
                     /gene="crcB"
                     /locus_tag="ACHY1N_004949"
     CDS             3399..3782
                     /gene="crcB"
                     /locus_tag="ACHY1N_004949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HFS4047096.1"
                     /translation="MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLAANLIG
                     AFIIGMGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VFVNLLGSFAMTALAFWLFSASTAH"
     gene            complement(3837..4046)
                     /gene="cspE"
                     /locus_tag="ACHY1N_004950"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(3837..4046)
                     /gene="cspE"
                     /locus_tag="ACHY1N_004950"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HFS4047097.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVIAL"
     gene            complement(4221..4781)
                     /gene="pagP"
                     /locus_tag="ACHY1N_004951"
     CDS             complement(4221..4781)
                     /gene="pagP"
                     /locus_tag="ACHY1N_004951"
                     /EC_number="2.3.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) palmitoyltransferase PagP"
                     /protein_id="HFS4047098.1"
                     /translation="MNVSKYVAIFSFVFIQLISVGKVFANADEWMTTFRENIAQTWQQ
                     PEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGLSRWDEKGNWHGLYAMAFKDS
                     WNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGP
                     VTFQMTYIPGTYNNGNVYFAWMRFQF"
BASE COUNT         1399 a         1286 c         1130 g         1342 t
ORIGIN      
        1 cgtcagaagg taaaccacaa atatttacaa ccttacgaaa tattgatctt aaccttctga
       61 ctatttttga agctgtatat gtacataaag ggatcgttaa tgcagcgaaa gtgcttaatc
      121 tgaccccctc ggcaatcagt cagtctattc agaaactgcg cgttatattc cctgacccat
      181 tgtttattcg caaaggccag ggtgtcactc ctaccgcatt tgcgatgcat ctacatgagt
      241 atatcagtca gggccttgag tccattcttg gcgcgctgga tatcgaagga agctatgata
      301 agcaacgaac gataactatt gcgaccactc cctcggtcgg agccctggtc cttcctgtca
      361 tctatcgggc gattaaaact cactatccgc agcttttact gcgcaacccg cccatcagcg
      421 acgcggaaaa ccaactcagt cagtttcaaa ccgatctcat catcgataac atgttttgca
      481 ccaatcgtac ggtgcaacat catgttctgt tcaccgacaa tatggtgtta atttgccgcg
      541 agggaaatcc actactctct ttagaagatg acagagagac tatcgacaac gctgcgcatg
      601 tacttctgtt accggaagag caaaatttca gcggtctgcg gcagagagtt caagaaatgt
      661 ttccggaccg gcaaatcaat ctcaccagct acaacatttt gacaatcgct gcactggttg
      721 ccaacagtga catgttagcg attattccca gccgttttta taacctgttt agccgctgct
      781 ggccgctgga aaaactgcct tttccgtcct taaatgagga gcaaatagat ttctctatcc
      841 actacaacaa attcagcctg cgtgatccca tcctgcacgg agtaatagat gttatccgta
      901 atgcattttg aaaaagtatt gttacagcca gatcacagcg cagaacgata aaatggcaca
      961 atccaacaac aattttacat tttcgcgacc gctttggctg ctttcaggtc cgtttcaatg
     1021 atatactgcc agtcgttaat tcaaaaatag ttgataatta caacaatcta ttgaattgaa
     1081 acgctttcct tcgtaattcg caactggaac acgcacgcta tgagtaaacc cattgtgatg
     1141 gaacgcggtg ttaaataccg cgatgccgat aagatggccc ttatcccggt taaaaacgtg
     1201 gcaacagagc gcgaagccct gctgcgcaag ccggaatgga tgaaaatcaa gcttccagcg
     1261 gactctacac gtatccaggg catcaaagcc gcaatgcgca aaaatggcct gcattctgtc
     1321 tgcgaggaag cctcctgccc taacctggcg gaatgcttca accacggcac agcaacgttt
     1381 atgatcctcg gcgctatttg tacccgccgt tgtccgttct gtgatgttgc ccacggtcgc
     1441 ccggtagctc ctgatgccaa tgaaccagtg aaactggcgc agaccattgc cgatatggcg
     1501 ctgcgttatg tggttatcac ctccgttgac cgtgatgacc tgcgcgatgg cggtgcccag
     1561 cactttgcgg attgcattac tgccattcgg gaaaaaagcc cgcaaatcaa aattgaaact
     1621 ctggtgccgg atttccgtgg tcgtatggat cgtgctctgg atattctgac tgcaacgcca
     1681 ccagatgtgt tcaaccataa cctggaaaac gtaccgcgta tttaccgtca ggtacggcct
     1741 ggtgcagatt acaactggtc gctgaagctg ctggaacgct ttaaagaagc gcatccggaa
     1801 atcccgacca agtctggtct gatggtggga ctgggtgaaa ccaatgaaga aattattgag
     1861 gtaatgcgcg acctgcgccg tcatggtgtg acgatgttaa cgctggggca atatttgcag
     1921 ccaagccgcc atcacctgcc ggttcaacgt tacgttagcc cggatgagtt cgacgaaatg
     1981 aaagccgaag cgctggcgat gggctttacc catgctgcat gcggtccgtt tgtccgctct
     2041 tcttaccacg ccgatttgca ggcgaaaggg atggaagtta agtaatcctg taataattac
     2101 ttacatctgt ctgataaaaa acccgctttt tgaagcgggt tttttgtatc gaacaagata
     2161 ttgagggagc gtcctgctcg ccacgtcact ctttatgaga gagcttttca gcctgaagat
     2221 caacgtctgc gccttttttc gccgcagcat cgtcatcatt catcgccttc ttgaaccctt
     2281 taatggccgc tccaaggtct ccgcccagcg tacgtaactt cttagtccca aacagcagaa
     2341 cgaccagcgc cgcaactact agcagtttgg taatactaat ctcacccata gataccttct
     2401 tgacatataa ccggcaacag aacgcgcctt aaaaaccaga gaatattaac ggtcattcga
     2461 cgcgcgcaca caatagcaat ctgtaacaag gtgaatcaag cgccgagtaa aaaaacatca
     2521 taataattgc ggcggcgcaa agcgacggtt gtttaagacg ggcagttgcg cgcgcacctg
     2581 acgcacacgt tcgggcgtca cttccgccat aatgagtgca ggcatttctg acgctgccgc
     2641 aatggtgacg ccaaagggat ctataatccg gctttgaccg atatttttgt tcccgcactc
     2701 ccccgccgcc accatataac aggtggtatc cagcgcacga gcggcaagca acgttgacca
     2761 atgatgctct ttgagcggcc cgcgaaccca ggcggcagga agtaccagga tttcagctcc
     2821 ctgtaatgcc tgtgccagcg ccagctctgg aaagcgtaag tcataacagg tcatcagacc
     2881 gaccttcatc ccctccacct cgagtaacgg agcgatttca ttaccagcat caacacggcg
     2941 tgattcctga atggcaaatg catcatagag atgcaatttg gcataacggg cgacgatgtt
     3001 tcctgcctgt agcgccacca gcatattcca tgcgcgcccc ggcgttgaag gaacatgaat
     3061 cgtcagaatt gtcgtcatca tgttacgttt actttctcgc cgtaaacgtc cgaggagttc
     3121 gccttccagc agctgtgctg atttaaccga tagatctgca tcatgatcat cgcgcgccag
     3181 caatgcttcc ggcaggacga acagcgatac gtcgttttcc gccgcctgcg ccatcaacga
     3241 ggcacaaatc tcagcgttct tttcccacac agatgtaaca gcaaactgtc ctgcggcaac
     3301 cagcattgcc acctcctgtc agagtcgtaa aattcgccaa cgacgattat tcggcgttac
     3361 acttatcact catacaaatc aaatagcagg attttgcagt gttacaactt cttttagcag
     3421 tttttattgg cggtggtacg ggaagcgtgg cgagatggct gttaagtatg cgatttaacc
     3481 cgctgcatca ggcgattccg ttggggacgc tggcagcaaa cctgattggg gcattcatca
     3541 taggaatggg attcgcctgg ttcagcagga tgacgaacat tgatccagtg tggaaagtat
     3601 taatcaccac cggattttgt ggcggtctaa caaccttctc aacattttcg gcagaagtgg
     3661 tgtttttgtt acaagagggc cgctttggct gggcgttact gaacgttttc gtcaaccttc
     3721 tggggtcttt tgccatgaca gcactggctt tctggctgtt ttcggcctca accgcacact
     3781 aaagaccaaa aaaaaacccg ctgattaagc gggttttgaa ttcttgctga cgtatcttac
     3841 agagcgatta cgtttgcagc agaagggcct ttggcaccgt tagtgatttc gaactctacg
     3901 cgctgacctt cagcaagagt tttaaaacca ttagtctgga ttgcagagaa gtgtacgaac
     3961 acgtctttgc tgccgtcttc cggagtaatg aaaccgaatc ctttggactc attaaaccac
     4021 ttaacgttac ctttaatctt agacatcaaa attaccttta catgaaaaat agacacaaat
     4081 gctgtgtcgg ttaccagtac accaattgtg gtacgctttg tccagtgcaa ctttactaaa
     4141 aagtgataaa agtcgcgtta tttttgatgt tacttatttt agctattgat tttaaagaag
     4201 ttactaaaac ttcatttgtc tcaaaactga aagcgcatcc aggcaaagta cacattgcca
     4261 ttgttgtagg tacccggaat gtaggtcatc tgaaaagtca ctgggccata acccacggag
     4321 gccaatggca gtagaaccgg gagagggatg taattccagt tatcgcgtgc cgttacgcca
     4381 gcggtgaatc ccagacctaa atgaaaattt tcatccgcca gcggtcgcca ggtactttcc
     4441 catccgtatc cggcaatcgg ttcccatttg ttccacgagt ccttaaatgc catggcatac
     4501 aggccatgcc agtttccttt ttcatcccaa cgcgacaggc caaaaccgcc accccacggt
     4561 cgctcgttat agcgatcggt tttttctttg tcgtaagcga aacgtgcatg ccaggtgatg
     4621 gcaggaatat ataaatcata atgttcaggc tgttgccagg tttgtgcaat attttctcta
     4681 aacgttgtca tccactcatc tgcgttagca aaaactttac caacgctgat taactgaata
     4741 aaaacaaagg aaaagatagc gacatattta ctcacgttca tttgtgacca taaaacattt
     4801 atcaaaaatc tactactagc atagcaaagc tacaattaac ataaccttaa tagacccaac
     4861 ataaagaata atctgaatag ctgctctatt tatttccgct tgttcaagtt aaatatttcc
     4921 gcgcatcgat taaagatgat gcgtcgtttt ctgcgatggg aatagtcaaa aaagaaaaac
     4981 caagtctttt ttgatgacaa aatgcaatca aggaaaaatt attttatttt ttaactagat
     5041 acaacaatca tcttaacgaa gtatataata taaatcgtca acctatgctc atgttagatt
     5101 attttttgag cgcacagccg cagctaacac cattgcaatt aacaaatttg catcaat
//
LOCUS       DAZUDJ010000160         5156 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.163, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000160 DAZUDJ010000000
VERSION     DAZUDJ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5156
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.163"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            43..438
                     /locus_tag="ACHY1N_004952"
     CDS             43..438
                     /locus_tag="ACHY1N_004952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HFS4047099.1"
                     /translation="MAKPFTHEQREELKARIIGLVRKNERMTISQLERATGAGWHSVR
                     RCLVDVLACGDLYMPGKYGVFTSEQVYRVWRKAAEKTTDQTLIRKLPDGEIRRYDRQQ
                     NIICGECRKSEVMLRVLAFYQGNFQEAIL"
     gene            496..852
                     /locus_tag="ACHY1N_004953"
     CDS             496..852
                     /locus_tag="ACHY1N_004953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047100.1"
                     /translation="MEIKPEDELSNIVLFPVKEDDPRNQVNFLYEASERAYCHHASVR
                     VDEKERQVRCKICGAVVEPFDWMLSVAKRETRLADDVRLLRQEERERRKNIEKLIQIE
                     RNAKARIRRATKSRTE"
     gene            946..1119
                     /locus_tag="ACHY1N_004954"
     CDS             946..1119
                     /locus_tag="ACHY1N_004954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047101.1"
                     /translation="MRKFKIIIETGIAGGDFEDEFEVDDDATPDEIHDEAKDIFFNYC
                     NYSYHEIKDEEEE"
     gene            1121..1297
                     /locus_tag="ACHY1N_004955"
     CDS             1121..1297
                     /locus_tag="ACHY1N_004955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047102.1"
                     /translation="MADFGSTKYSVSFEEWHELLMDYAELRGGSAADAEAWRDDYEAG
                     KTAVEAYCDEWGDE"
     gene            1294..2241
                     /locus_tag="ACHY1N_004956"
     CDS             1294..2241
                     /locus_tag="ACHY1N_004956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ead/Ea22-like family protein"
                     /protein_id="HFS4047103.1"
                     /translation="MSEIDYQALREAAEKATKGCYIVGHTSGNQHGNITGVFVCQKWK
                     GEPGGVIAECHVNCLVETDAQAYANAEFIAAFNPNVALALLDERERNQQYIKRRDQEN
                     EDIALTVGKLRVELEAAKSKLNEQREYYEGVIADGSKRIAELEKQCAEWERKALSNFE
                     ECAAMAERIEEMQTKSAPDSFGIIGENIRTQDNRITSDPMFCVYQKREIVVDADYDHD
                     RIVWVDEDGNEANKRHSRRLELLHENFREPPEKWRRVAVKDIDEFVTCCFTEQGCKDY
                     LAVNGHNLRLPFIYVKSGFRNAEYIGIRNWLAGIRIKGE"
     gene            2243..2421
                     /locus_tag="ACHY1N_004957"
                     /pseudo
     CDS             2243..2421
                     /locus_tag="ACHY1N_004957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_305741.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2755..3099
                     /locus_tag="ACHY1N_004958"
     CDS             2755..3099
                     /locus_tag="ACHY1N_004958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047104.1"
                     /translation="MTTITREQLIAHAEETIETQRLCIPGTIDHDIIRTYKMDIAVLE
                     IALVSLAAEPAGKLHEYKPVGYQRLVDELTMLVKQLTWQLRKAKPDCKLPDKAMSYLE
                     RNGLISVEDILR"
     gene            complement(3304..3603)
                     /locus_tag="ACHY1N_004959"
     CDS             complement(3304..3603)
                     /locus_tag="ACHY1N_004959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFS4047105.1"
                     /translation="MTYEVIITPEAEQQIINLHRYITEKAGNVIADNYANALLDYLDG
                     FSTFPHRGNKRDDIRQGMRVTHFRHRTIIAFAVDSRKVFIVGIYHGGQSYETDFL"
     gene            complement(3609..3866)
                     /locus_tag="ACHY1N_004960"
     CDS             complement(3609..3866)
                     /locus_tag="ACHY1N_004960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051983 - regulation of chromosome
                     segregation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
                     /protein_id="HFS4047106.1"
                     /translation="MRTTQQFSITLTNEMADMVRARVASGAYASESEVIREGLRALNE
                     RDKAIEAWLTHSAAPSLDSIRENPNNGRSISQVRAAIRSGK"
     gene            4002..4274
                     /locus_tag="ACHY1N_004961"
     CDS             4002..4274
                     /locus_tag="ACHY1N_004961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047107.1"
                     /translation="MAHNTKHHNSDIAPASRQGRCSHTFKYDWYQHDPCTEEQAEWLI
                     HNYRRRGYEFKKALSLDYRHWIIYVRLLYSERPPRPSRTFQQRIWR"
     gene            4276..>5156
                     /locus_tag="ACHY1N_004962"
     CDS             4276..>5156
                     /locus_tag="ACHY1N_004962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HFS4047108.1"
                     /translation="MRVLLRPVLVPELGLVIVKPGRESMPVFHNTRVLVEPEPKSMRN
                     LPSGVVPAVRQPLVEDKTLLPFFSNARVIRAAGGAGALSDWLLRHIKSCQWPHGDYHH
                     SETVIHRYGTGAMVLCWHCDNQLRDQTSESLGQLAQQNLTAWMIDVIRHAISGAQERE
                     LSLAELSWWAVRNQVADALPEAVLRRSLGLRAEKIRSMYRESDIVPGEQTATSILKQR
                     TKNLAPLPHAHQQKPPQEKTVVSIAVDPESPESFMKRPKRRRWVNEKYTHWVKTQPCA
                     CCGKPADDPHHLIGHGQG"
BASE COUNT         1477 a         1094 c         1382 g         1203 t
ORIGIN      
        1 tccggtcgta ttgtgtcgga aaagtgattg ccggaggcgc ttatggcgaa accttttaca
       61 cacgaacagc gtgaagaact gaaggcccga attatcgggc tggtacgcaa aaatgaacgc
      121 atgacgatat cacaactgga gagagcgacg ggagcaggct ggcattcagt cagacgttgc
      181 cttgtggatg tactggcttg tggcgattta tacatgcccg gtaaatacgg tgtttttaca
      241 tcagaacagg tgtatcgcgt atggcgtaag gcagcggaga aaacaaccga ccagacattg
      301 attcgaaagt taccagacgg agaaatacgc cgctacgaca gacaacagaa cataatctgt
      361 ggcgagtgcc ggaagagtga agttatgctg cgtgtactgg ctttctatca gggtaatttt
      421 caggaggcga tactgtgaat gaaattagct atcaggcttc aattaccgct ggcattcaca
      481 tcaaaggaga agagcatgga aataaaacca gaagatgagt taagcaatat cgttttattt
      541 ccggtaaaag aggatgaccc acgtaatcag gttaattttc tttatgaggc atcggaaaga
      601 gcatattgtc atcacgcctc tgttcgggtt gacgaaaaag agcgtcaggt ccgctgtaaa
      661 atctgcggtg cagttgtgga gccgtttgac tggatgctct ctgtggcgaa aagagaaacc
      721 agactggcag atgatgtaag gctcttgcgc caggaggagc gggaaaggcg aaaaaatata
      781 gaaaagctaa ttcagattga gcgtaacgcg aaagcgcgga tacgcagggc gacaaaatcc
      841 agaactgaat aattaaattt agctctgtta aaaatttaat ccttaaccgg agggatttct
      901 gcaccctaag aacatcagga ggccgcccga aagggcggta gttaaatgcg aaagtttaaa
      961 ataattattg aaacgggaat agccggtgga gatttcgagg atgaattcga agtggatgat
     1021 gatgcgacgc ctgatgaaat acatgacgaa gcaaaagata ttttctttaa ctactgcaat
     1081 tactcatatc acgaaataaa agacgaagag gaggaataaa atggctgatt ttggttcaac
     1141 taaatacagc gtcagttttg aagaatggca tgaactgtta atggactatg cagagttacg
     1201 tggtggcagt gctgctgatg ctgaagcatg gcgtgatgat tatgaagcag ggaaaactgc
     1261 ggtcgaagca tattgtgatg agtggggcga tgaatgagcg agattgacta tcaggcgctg
     1321 cgtgaagcag cagagaaagc aactaaagga tgctacatcg tagggcatac atcgggcaat
     1381 cagcatggga atataacagg agtttttgtt tgtcaaaaat ggaaaggaga acccggtggc
     1441 gtgattgcag aatgtcatgt taactgcctg gttgaaacag atgctcaggc ttacgcaaac
     1501 gctgaattta ttgctgcctt taatccaaat gttgcgctgg cgcttctgga tgaacgggaa
     1561 agaaaccagc aatacatcaa acgccgcgac caggagaacg aggatattgc gctaacggta
     1621 gggaagctgc gcgttgagct tgaagcagca aaatcaaaac tcaacgagca gcgtgaatat
     1681 tacgagggag taatcgcgga tggaagtaag cgcatagcag aactggaaaa acaatgcgcc
     1741 gaatgggagc gaaaagcatt aagcaacttt gaagagtgtg ctgcgatggc tgaacgtatc
     1801 gaagagatgc agacaaaatc tgcaccagat tcgtttggca tcatcggtga aaatattcga
     1861 acacaggaca atcgaataac gtcagatccc atgttttgtg tgtatcaaaa gcgcgaaatc
     1921 gttgttgatg ctgattatga ccatgaccgg attgtctggg ttgacgaaga tggcaatgaa
     1981 gccaataaac gccatagtcg tcgtctcgag ctacttcatg aaaactttcg agagccacca
     2041 gaaaaatggc ggcgcgttgc tgtgaaagat attgatgaat tcgttacctg ctgtttcacc
     2101 gaacagggtt gtaaagacta cctggcagtc aatggtcaca atcttcgctt gccatttata
     2161 tatgtaaaaa gcggtttcag gaacgctgaa tatatcggca taagaaactg gcttgctggc
     2221 attcgcatca aaggagagtg atatggcgtt aacacaccgc gaactctgtc agattgcgta
     2281 caagttcctt aagcgcaacg ggttcaaggt ttgttttcat gaccgcttta tagctgtaac
     2341 cagtaccgga gaacagccag atgctatggg attcagaaat tcagcatcat gcctgataga
     2401 ggcgaaatgt tctcgtgctg acttgttggc agatagaaaa aagcgttttc gtaaaaatcc
     2461 gtctcttgga atgggcgact ggcgattctt tattagtgag ccgggaatta tttcaattga
     2521 ggatttacct cctggctggg gattacttca cgttgttaac ggaagagtac ggaaagtaca
     2581 tgggtggccc aagggtaatt gctgttgggg taatcctgac gataagccat ttactggaaa
     2641 taagcaggtt gaatgcgatt acatgttgtc tgcattaagg cgcatggagt tgagagggca
     2701 ccttaatgaa atatatgacg gtgtaattgt taataagaaa gaaggaaacg cggcatgacc
     2761 actattacca gagagcagtt aatagctcac gcagaggaga ctattgaaac acagagactg
     2821 tgcataccgg gcacaatcga ccatgacatc atccgcacat ataagatgga tattgctgtt
     2881 ctggaaatcg cactggtatc gctggcagca gagccagccg gtaaattgca tgaatacaaa
     2941 ccagtgggat atcagcgtct ggtcgatgag ttaaccatgc tggtaaagca gttaacctgg
     3001 caactgagga aagcgaagcc agactgcaaa ttaccggata aggcgatgag ttatctggag
     3061 cggaacggac tgataagcgt ggaggatatt ttacgatgac ctggcctgaa gcattcacaa
     3121 cggtaggaat tgcgatggcg gtggcgctgg tggtgtattc gatttgccgc tggggataaa
     3181 tcgccgaaaa aagatcccga cataaacatg agccgggatc tttgatttat atagcctacg
     3241 aatccgccag taagagaggg ggcggacggt taattctaac accggaatga tgtgggtaaa
     3301 agtttataag aaatcggttt cataactttg cccaccatga tagataccga caataaagac
     3361 ttttctgcta tcaacggcaa aagcaataat cgttctgtgg cggaaatgag ttacccgcat
     3421 cccctggcga atatcatcgc gtttattgcc ccgatgcggg aatgtagaaa acccatcaag
     3481 ataatcaaga agcgcattgg cataattgtc agcaatgacg ttccctgctt tctccgttat
     3541 atacctgtgc aggttgatta tttgttgttc ggcctcagga gtaatgatga cttcatatgt
     3601 catgcagatt acttcccgga tcgaatcgcg gcgcgaacct gtgaaatgga gcgtccgttg
     3661 tttggatttt cgcggataga atcaagagag ggggcggctg aatgcgttaa ccacgcttcg
     3721 attgctttat cgcgctcatt cagtgcgcga agcccttcac gaatgacctc gctttctgaa
     3781 gcataggcac cggaagccac acgggcgcgc accatgtcag ccatttcgtt agttaatgta
     3841 atgctgaatt gttgggttgt acgcatggta aacctcacgg agtaggatag aacaccattc
     3901 gatgatagca cgttgcctgt tgacgacaac agaaatcaga gacaatattg ccgcacgcca
     3961 gcttgaacaa ctggcacctg ctgcgccagc agagaaaacc gatggcgcac aataccaaac
     4021 atcacaattc tgatatcgcc cctgccagca ggcaagggcg gtgttctcac acattcaaat
     4081 atgactggta tcagcacgat ccctgcactg aagaacaggc cgaatggctg attcataact
     4141 accgcagacg tgggtatgag tttaagaaag cccttagcct cgactaccgt cactggataa
     4201 tctacgtcag gctcctttat tccgaacgcc cgccgcgtcc gtcccgcaca ttccagcaac
     4261 gcatctggag gtaacgtgcg ggtattactt cgacctgttc tggtaccgga actcgggctg
     4321 gtgatcgtta agccgggtcg tgaatccatg ccggtattcc acaatacccg ggtactggtg
     4381 gagccggaac cgaaaagcat gcgtaatctg ccgtccgggg ttgttcctgc cgttcgccag
     4441 ccgctagtgg aagacaaaac attgctgccg tttttcagta acgcacgggt gattcgtgct
     4501 gctggtggtg ctggtgcatt gtctgactgg ctgttgcgcc atattaaatc ctgccagtgg
     4561 ccacacggcg attatcatca cagcgaaacc gtcattcacc gttatggtac cggcgcaatg
     4621 gtgttgtgct ggcactgcga caaccagctg cgcgaccaga catccgaatc actcgggcag
     4681 cttgctcaac aaaatctgac agcctggatg attgacgtca tacgtcacgc aataagtggt
     4741 gcacaggaac gggaattatc tctggctgaa ttatcctggt gggcggtccg caatcaggtg
     4801 gcggacgcgc taccggaagc ggtattacgt cgttcgctgg ggttgcgtgc ggaaaaaatc
     4861 cgctcaatgt accgtgaaag cgacatcgta ccgggagagc agaccgccac cagcatactg
     4921 aagcagcgca caaaaaatct tgcgccgctg cctcacgctc accagcaaaa accgccacag
     4981 gaaaagacgg tggtcagcat tgccgttgat cctgagtctc cggaatcttt catgaaacga
     5041 cctaaacgtc gccgctgggt taacgagaaa tacacgcact gggtgaagac acagccgtgt
     5101 gcgtgttgtg gtaagcctgc tgacgatccg catcacctga ttggtcatgg tcaggg
//
LOCUS       DAZUDJ010000161         5078 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.164, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000161 DAZUDJ010000000
VERSION     DAZUDJ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5078
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.164"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..358)
                     /locus_tag="ACHY1N_004963"
     CDS             complement(<1..358)
                     /locus_tag="ACHY1N_004963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB-fold-containig protein"
                     /protein_id="HFS4047109.1"
                     /translation="MTLTLLTAYNVPYLAALTFVLLTGIAELIALLCGHSLSSAMDTP
                     DLPEGLTGEALDWLNIGRIPLLIVLCMLAGFFGISGILLQGLIIHLLQAPAPNILLAP
                     LCLLLTCPLVHRTGRLI"
     gene            complement(625..1290)
                     /locus_tag="ACHY1N_004964"
     CDS             complement(625..1290)
                     /locus_tag="ACHY1N_004964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="traC"
                     /protein_id="HFS4047110.1"
                     /translation="MTILSLENPVILLLENMLEALSTAPDSINNERRRRRYLLNWLES
                     ARQMSAFRGMAEEFTTLRKLLATNTDIPVANTLKSLLESGNNAALYDLYRFRSALSAC
                     RSLGWQIGTCAWNDQLLSETLSRAQTGKRHILQLNSTRDTFSTTGRMLRPVAFSLIHP
                     ASLESSEVEEIFRDEGFILAHGRECSLNGSGRNMLSRILHVGHSGLPKAEWGIDHSNH
                     LLH"
     gene            complement(1431..2072)
                     /locus_tag="ACHY1N_004965"
     CDS             complement(1431..2072)
                     /locus_tag="ACHY1N_004965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0140673 - transcription elongation-coupled
                     chromatin remodeling [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="HFS4047111.1"
                     /translation="MCLSELQAGLNEDQPLFPTHALCIRRSQQHRSPSAGIDFRGAFR
                     ILNIRELHQRNWYLAQYIPAGKNREHLFSWLSEQHVLPWTPLILKKVRRTDKVCGYRR
                     HIHAVFPGYFFLKADPERHSFTHLRRHSAFLNFVKMAGEIKTVREDIVQSLMKVYPDP
                     ALNPAAREELDAASTLWLTKARYQYLLRLDAPPLPESRIALLLHLVSDDGALT"
     gene            2781..3812
                     /gene="repA"
                     /locus_tag="ACHY1N_004966"
     CDS             2781..3812
                     /gene="repA"
                     /locus_tag="ACHY1N_004966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication initiator RepA"
                     /protein_id="HFS4047112.1"
                     /translation="MAGLKNTPYNAVHWSQLAPEEQIRFWEDYEAGRATSFLVEPERK
                     RTRRRRGEHSTKPKCENPSWYRPARYKELSGQLGHAYNRLVKKAPVTGEQSLRMRMSR
                     HPFYVQKRTFVGRKYAFRPEKQRLLDAIWPVLVSFSDAGTHTVGMSVTRLAKEISPKD
                     SKGNVIPELEVTVSRLSRLLAEQVRFGVLGVSEETMWDRETRQRLPRYVWITPAGWQM
                     LGVDMVKLHEQQQKRLRESEIRQQLIREGVLREDEDISVHAARKRWYLQRSQDALKHR
                     RAKAAASKRARRLKKLPADQQIHEMAEYLRKRLPPDEAYFCSDDHLKRLAIRELRQLE
                     LTLAAPPPH"
     gene            complement(4772..>5078)
                     /locus_tag="ACHY1N_004967"
     CDS             complement(4772..>5078)
                     /locus_tag="ACHY1N_004967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047113.1"
                     /translation="CRFWPKESVAVGDTINLSNYEHIEFSFNSFSKDVCREQNSDIYK
                     IFFKIVALNNSIVVSENMFTQKNFLEHNTFFSVTGIDESLYEKHIIFITLKAIPPQK"
BASE COUNT         1378 a         1232 c         1317 g         1151 t
ORIGIN      
        1 caatcagtct gccggtgcgg tgtacgagag gacatgtcag cagcaggcaa agtggtgcaa
       61 ggagaatgtt cggggcagga gcctgcagca gatgaataat aagaccctgc aggagaatgc
      121 cggatatacc aaaaaaacct gccagcatac agaggacgat cagcaggggg atccgtccga
      181 tgttcagcca gtccagcgcc tctcctgtca gcccctccgg taaatcaggt gtatccatag
      241 ctgaagagag ggagtgtccg cagagcaggg cgataagttc agcgatacca gtaagcagaa
      301 caaaagtcag ggctgccaga tagggtacgt tatacgcggt aagtaacgtc agtgtcattt
      361 ttcctcctgt ggcaggtcag tcaaacaaca ttatggcgtg aagcttccgc ttctttaatt
      421 gtcagaagaa gcatatcgtc agtcatcaga agacaagggg atgtctgcag gaggggatga
      481 taacaactga agcctcacgc cggaatgcgc tttatgacaa ccggagagga cggataataa
      541 aaaatgggac atccacatca gcaaaccgcg atttgcgaaa aaaagtcagc ggagagtggc
      601 tgccgttgtg gctgtcccgg tatttcagtg taacaggtga ttgctgtgat ctatgcccca
      661 ttcggctttc ggtaaacctg aatgccccac atgaagaatg cgtgacagca tgtttctgcc
      721 gctgccgttc aggctgcatt cgcgtccgtg cgcgagtata aaaccttcat cccggaatat
      781 ctcttccact tctgaagatt cgagggatgc cggatgaatt aatgaaaatg ccaccggtct
      841 gagcattctg cccgtggtgg aaaaggtgtc tctggtactg ttcagctgca ggatatgacg
      901 tttacctgtt tgcgcacggg aaagtgtctc actcagcagc tggtcgttcc atgcgcacgt
      961 gccaatctgc catcccagac ttctgcacgc ggaaagagcc gagcggaagc ggtacaggtc
     1021 gtataatgct gcgttattgc cactttccag cagtgatttc agcgtatttg ctaccggtat
     1081 gtccgtattg gtggccagca gttttcgcag agtcgtaaac tcttctgcca ttcctctgaa
     1141 tgcgctcatc tgacgcgcag attcaagcca gttcagcagg taacgccggc gacgccgttc
     1201 gttgttgata ctgtccgggg cggtggagag tgcttcgagc atattctcca gtaacagaat
     1261 gacagggttt tccagggata gaatggtcat aaaggcgtcc tgaaaaaatg cccgacagcc
     1321 gctctccgta caccgtaagg tgtcaccggt gccgggcatt gtggaaacag aaggaaaaaa
     1381 aatcccggcc ataaaggccg ggaaaagtcg tcaaattaag acagcaattt tcatgtcaac
     1441 gctccgtcat cagataccag gtgcaggagc agggcgatcc tcgactccgg cagaggcggt
     1501 gcatcaagcc ggaggaggta ctggtaacgc gcttttgtca gccagagggt ggaggcagca
     1561 tccagctcct ccctggctgc cggattgagc gcaggatccg ggtacacttt catcaaagac
     1621 tgaacgatat cctccctgac ggttttgatt tcaccggcca ttttcacgaa gttcagaaag
     1681 gcactgtgac ggcgaaggtg agtgaagctg tggcgttcgg ggtctgcttt caggaaaaag
     1741 taaccgggaa acacggcgtg tatatgtcga cggtaaccgc agactttatc cgtgcggcgg
     1801 acttttttca gtatcagggg tgtccaggga aggacgtgtt gttcggaaag ccaggaaaag
     1861 agatgttcgc ggtttttgcc ggcagggatg tactgagcca gataccagtt gcgttgatgt
     1921 aattctctga tattcaaaat ccggaacgct ccgcgaaaat cgatccccgc agaggggctt
     1981 cgatgttgtt gtgaacggcg aatacataaa gcatgtgtcg gaaacagcgg ctgatcctcg
     2041 ttcagcccgg cctgcagttc tgacaggcac atgatttacg cactcttgta agccttgtgg
     2101 acggtttcga ggccggcgaa aaccgacaaa acctgcaaac aggattaatg gctggcaaac
     2161 atattacata aggatatatc tgtggcaaga gcgaagataa gtagttaaat agatcgttat
     2221 atttgataaa gcagcatatt acgctgggtt gtgtgaggtg tttggatgat tagatcgtag
     2281 atcgtagatc gtaatcacaa gatcgattca tccaaaaaac atgaaaaaca cagcataaaa
     2341 gatcgtttgt ggaattgtct attttttgac acagttcaaa aaaacgacgt tttttaggtg
     2401 gttaatgaga ggcctggtaa atcagagaaa tcgtgttggc ttttcaaagc ggtggaaaag
     2461 gggtatattg cggatcgtta tgcagtggct tttgggatcg tcaggatccg ggaagtcaga
     2521 aaatggctgg atgcgccata aggcattcag gacgtatggc agaaacgacg gcagtttgcc
     2581 ggtgccggaa ggctgaaaaa agtttcagaa ggccataaaa ggaaaacccc cataatcttc
     2641 tcatcgaact tggcggaacg ttagaagatt atgggggcct cacagaatac gggataagta
     2701 tatatgaaac cgtgtcagag attcaaccct tcgcagtgta ttaacgcacg gcattctgtt
     2761 tccgccataa gcgacagctt gtggcaggtc tgaagaatac tccatataac gcagtacact
     2821 ggagtcagtt agcacccgaa gagcagatcc gtttctggga agactatgaa gcgggaaggg
     2881 cgacctcttt cctggttgaa ccggaaagga agcgcaccag gcgccgtcgt ggcgaacact
     2941 ccactaaacc caaatgcgaa aatccgtcct ggtatcgtcc tgcgcgctat aaggagctga
     3001 gcgggcagct cgggcacgcc tacaaccgtc tggtgaaaaa ggccccggtg accggcgagc
     3061 agagcctgcg tatgcgtatg tcgcggcatc ctttttacgt gcagaaacgg acgttcgtcg
     3121 gtcgcaaata tgctttccgg ccggaaaaac aacgcctcct cgatgccatc tggccggttc
     3181 tggtcagctt cagtgatgcc ggcacacaca ctgtggggat gagtgtcact cgcctggcta
     3241 aagaaatcag tccgaaagac agtaagggaa atgttattcc ggaactggaa gtgacggtct
     3301 cccgtctttc ccgtctgctg gccgaacagg tgcgttttgg tgtgctgggt gtttcagagg
     3361 aaacgatgtg ggaccgtgaa acccgccagc gtctgccgcg ctatgtctgg ataacaccgg
     3421 ctggctggca gatgctgggc gtcgacatgg taaaacttca cgaacagcag cagaaacgac
     3481 tgcgtgaaag tgaaatccgc cagcagctca ttcgggaagg tgttctgcgt gaggatgaag
     3541 atatctccgt acatgcggcc agaaaacgct ggtatctgca gcgcagtcag gatgcgctga
     3601 aacaccgtcg tgcgaaagca gcagccagta agcgcgccag acgcctgaag aaactgcctg
     3661 ccgaccagca gattcatgag atggcagagt atctcaggaa gcgtctgccg ccggatgaag
     3721 cctatttttg ttccgatgac catctgaagc gactggccat cagggagttg cgtcagcttg
     3781 aactgacgct ggctgccccg ccaccgcact agacagcacc attccctcag cactgaatca
     3841 tcgccagccc ctccggggct ttcggcgcag gtatcgctca gcccaaaatc cgcagtaatc
     3901 accttaaatc ccctcagagg ggcatatttg ctcataaaac cacgcatcag tcatcagaac
     3961 gtggccacgt tgtttcagtt atccacataa atccgcaaac aaagaacttt aagaagctgc
     4021 aaacctgaaa cagcaaacct gcaatatagt cttaacccca ttatttaatc ccctgcgttg
     4081 cttcgccgca gcgaaagtct ttatctctga aaccactgtg aacaaacaca aagaggcctt
     4141 cgcttgcagc ggccaaggcc gcgccgctca gaatctaaaa gcacctccca cgctgacgcg
     4201 cgggccccga acctcaccgt tctggaacca caacaaaaaa acatcaggaa taaaaacacc
     4261 acacaaacgc agcaccgtgc ccacccctca taactgaaaa gcgccgccgc cccggcccaa
     4321 agggccggaa cagagtcgct tttaattatg aatgttgtaa ctaaacatca tcatcgcttt
     4381 aagaccccat ttgtctagca gggcgatggc ccactgcgtg aaccatcacc ctgcacacag
     4441 ggtattttat gtgcaattgt caaccactga atcggaaccc cagaggggcc cccacgattc
     4501 agaagttgac aatttaagca cagggactac atgagaaaaa tcgtggttcg tctgtcatac
     4561 acgcgcgtaa gcggcactga tagccctctt acgcggaaat acgcccataa gcgctaactt
     4621 aagggttgaa ccgacgccac ggtgtctcgt taagacttca attgcgtttt gtaggcagtc
     4681 agggatactg tcccatgaat ggccacctgt aagctccaga taaccatttt tgttattctc
     4741 cacaacgaat tccgcatacc ggaaatcagc gctacttctg gggaggaatg gccttaagag
     4801 tgataaagat tatatgcttt tcatagagag actcatctat gccggtaaca ctgaaaaatg
     4861 tattgtgttc caagaagttt ttttgagtga acatattttc gctcacaaca atcgaattat
     4921 tcaaagccac aattttaaaa aatattttat atatatcact attttgttca cgacagacat
     4981 ctttactaaa agaattaaag ctaaattcaa tatgttcata attagataaa tttattgtat
     5041 ctccaacagc tacactttct tttggccaaa aacgacat
//
LOCUS       DAZUDJ010000162         4997 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.165, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000162 DAZUDJ010000000
VERSION     DAZUDJ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4997
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.165"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(10..1172)
                     /locus_tag="ACHY1N_004968"
                     /pseudo
     CDS             complement(10..1172)
                     /locus_tag="ACHY1N_004968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS3 family transposase"
     gene            1239..1766
                     /locus_tag="ACHY1N_004969"
                     /pseudo
     CDS             1239..1766
                     /locus_tag="ACHY1N_004969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309324.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
     gene            1763..2749
                     /gene="ycdU"
                     /locus_tag="ACHY1N_004970"
     CDS             1763..2749
                     /gene="ycdU"
                     /locus_tag="ACHY1N_004970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcdU"
                     /protein_id="HFS4047114.1"
                     /translation="MIPDYLTFIRFQDKRNLIYIYAIGLILIGFYWKNAGFTFPSEDI
                     GVVSGILALVLYNFIFDLKAYWAYKCVTKNIDFSWFKKKQNHKIELFLTQPLVAGFLS
                     LIMLSAMSWGLYQLLPSLYALFLISLLGPLVIFLLFRMIRTSYVKQVAISVAKKVKYK
                     SLTRYVLLSVCISTVVNLLTISPLRNSDSFVTEGQWLTFKSIIALLILCGVVLAINLF
                     FLRFSKRYAFLGRLFLQEIDLFFSSENALSTFFAKPLWLRLFILLVIEMMWITLVSVL
                     ATLVEWRIWFEAYFLLCYVPCLIYYFFHCRFLWHNDFMMACDMYFRWGHFNK"
     gene            3116..4318
                     /locus_tag="ACHY1N_004971"
     CDS             3116..4318
                     /locus_tag="ACHY1N_004971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4047115.1"
                     /translation="MAVLTDTKARHIKPDDKPLPHGGITGLTLHPSSVKGRGKWVFRY
                     VSPVTQKRRNAGLGTYPEVSIAEAARTARIMREQLAAGDDPLEIKKAESEKVAIPTFA
                     DAARRVHAELSPGWENPKHVRQWLSTLENYAFPQLGAKTLDSITAADVAETLRPVWLT
                     LSETASRVKQRIHVVMQWGWAHGFCVANPVDVVDHLLPQQTRGRDEHQPAMPWRQLPL
                     FVATSVYTDEPYNVTRALLLMVILTATRSGEARGMRWAEIDFHKRVWTIPAERMKARL
                     QHRVPLSRQAIYILENIRGLHDELVFPSPRKQQILSDMVLTSFLRKKKAVSDIPGRVA
                     TAHGFRSTFRDWCSEQGYSRDLAERALAHTLKNKVEAAYHRTDLLEQRVPMMQAWADY
                     VMSQIVNK"
     gene            complement(4506..>4997)
                     /locus_tag="ACHY1N_004972"
     CDS             complement(4506..>4997)
                     /locus_tag="ACHY1N_004972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047116.1"
                     /translation="NLISLDHEYPESCLQNDTNTYLLGRVIFLYNSMIYKFINCQEHE
                     TNNIHSAMINNLLQEVDIALGKINNIIDSRNISAPHELANILTREKILTTREKKGNLI
                     SLFDGFTLFHCVGMITFLIHYLRTPEEKVENIFMLYGADKNNKLRRRLIYDALGIIQS
                     QQE"
BASE COUNT         1239 a         1059 c         1229 g         1470 t
ORIGIN      
        1 gacacaggcc taagcgaggt tcttgttttc aaattgttcc ggactgaggc cgccacacca
       61 actgtgccgc cgccaccgat tgtaatcaca ttcgatataa ttaaacaccg ttgcccgcat
      121 tatttcccgg ctgataaagt gttctccatg gatacattcc actttcagcg aatgaaagaa
      181 gctttccacg caggcattat cgtagcagca accttttgcg ctcatacttc cacgcagatt
      241 atgccgcttc agttgcgcct gataatctgc tgaacagtac tggcctccac ggtccgtgtg
      301 aacgataacg ttccggggcc tcttacgccg ccacagcgcc atctgcaggg catcgcaggc
      361 cagttgcgcc gtcatgcgtg gcgacattga ccagccaata acggcacgtg accacaggtc
      421 aatgaccact gccagataca gtcagccttc atctgtacgt aagtacgtga tgtctcctgc
      481 ccacttctgg ttcgggccac tggcgtaaaa atcctgctcc aacagatttt ctgacacagg
      541 caggccgtgt gcgcggtagc tgaccgggct gaacttccgg gaggcctttg ccctcagtcc
      601 ctgacggcgc aggcttgccg ccacggtttt tacgttaaag gggtacccct gagcacgcag
      661 ttcatccgtc aggcgtgggg caccgtaacg ctgttttgac cgggtaaaag ccgcgaggac
      721 aacgctgtcg cagtgttggc ggaactgctg acgcgtgctt atccttgtcc gccgctgaca
      781 ccacgtatac cagccgctgc gggccacccg gagcacgcgg cacattgctt tgatgctgaa
      841 ctcagcctga tgtttttcaa taaagacata cttcatttca ggcgcttcgc gaagtatgtc
      901 gcggcctttt ggaggatagc cagctcttca tcccgttctg ccagctggcg tttgagacgt
      961 gcaatctcgg tagacatctc cagttcacgt tcagaagacg tctgctgatt ttgctgttta
     1021 ctgcgccagt tgtagagctg tgattcatac aggctgagtt cacgggctgc ggcagtaaca
     1081 ccgatgcgtt cagcaagctt cagggcttca ctgcgaaatt caggcgaatg ctgtttacgg
     1141 ggttttttac tggttgatac tgtttttgtc atgtgagtca cctctgactg agagtttact
     1201 cacttagccg cgtgtccact attgctgggt aagatcaggc ggttaaaggc atcaaccgcg
     1261 aacaactgca gacgatgatt acggaatcag gcattgcgct ggatattagc tgtgataaca
     1321 cgccgcgcca gcaggttatt gggggaacgc aggctgcgtt gaatgaattt gccacgctgc
     1381 tgatggccgc tggatacgaa ccggttaaac tcggtgtgag cggtgcctgg cacacgcgtt
     1441 tgatggaaga cggcgttcag gcaatgcgcg attatcttgc cggactggat atcgcttcgc
     1501 cagagcatca ggttctgatg aacgtaacag caaaaagcga ggtcgctccg tcaattatca
     1561 aagaaaatct ctcattacac ttaactcata cggtgaaatg gactgaatct ttcgatacat
     1621 ttctgaatat gccaaccccg gtagctttcc ttgaaataag taataagccc tatttgggga
     1681 atatgttaaa tgattttgct ggcgtggttc agcaacgagt tatgcattgt cgtaaagcat
     1741 ttagtgatgc aaaggtattc aaatgattcc tgattattta acttttattc gctttcagga
     1801 taaacgaaat ctgatataca tttatgctat tggacttatt ctgataggct tttattggaa
     1861 gaatgcaggg tttacttttc catcagagga tattggtgta gttagtggga ttctggccct
     1921 ggtgctgtat aattttattt ttgatctcaa ggcgtactgg gcttataaat gcgtcacgaa
     1981 gaatatcgat ttttcgtggt ttaagaaaaa gcagaaccac aaaatagaat tatttcttac
     2041 acaacctctg gtggcaggat ttctgtcgtt aatcatgttg agtgcaatga gttgggggct
     2101 ataccagctt ctaccctcgt tatatgcgct gttcctgatt tcgttacttg ggccgttggt
     2161 catctttctg ctgtttcgga tgatccgcac cagttatgtc aagcaggtcg ctatttcagt
     2221 agcgaaaaaa gtaaaatata aaagtctgac tcgctatgtg ctgctttcgg tgtgcatctc
     2281 aacggttgtt aacctgctta ctatcagccc gttgcgtaac agtgattctt ttgtgacaga
     2341 ggggcagtgg ttaacgttta aatcgataat tgcattgctc attctttgtg gcgtagtgtt
     2401 ggcgattaat ctgttttttc tgcgcttctc caagcggtac gcttttctgg gcaggctttt
     2461 tttgcaggaa atcgatctgt ttttctccag tgaaaatgcg ttgtcgacct tttttgccaa
     2521 gccgctttgg cttcggttat tcatattgct ggttattgaa atgatgtgga ttacgctggt
     2581 gtcggtattg gcaacgcttg tggaatggcg gatttggttt gaagcctatt ttttactctg
     2641 ctatgtaccg tgcttaattt actatttttt ccattgtcga ttcctctggc ataacgattt
     2701 tatgatggca tgtgacatgt atttccgttg ggggcatttt aataagtgag gaagttacag
     2761 gaagtgacca gataacgcat atatgttctc tactatcttg cgcattttga ttgttgactg
     2821 agtaaccaga cagttgatgt gcacaatttc ccctcgccct aacagacgtg ggcgggggca
     2881 cccggtgtgt gcaatatacg aaaaaaaagc ccgtactttc gtacgggctc ttctttaaat
     2941 atggcggtga gggggaccgc ctgaaataaa tctgacttaa tccaggggtg ttatataatt
     3001 taattataaa caatgtatta cactttttgt tgtccgatat tatctaatgt attcttagtg
     3061 aagcgagaga ctaatggcat actggatggc ataccagagt gacgggaatt agcgtatggc
     3121 agtattgacg gatacgaaag caagacatat caaacctgat gacaaaccat tgccccatgg
     3181 gggaattacc ggactgaccc ttcatccttc ttcagtaaag gggcggggga aatgggtttt
     3241 tcgttatgta agtccggtga cacaaaaaag acgtaatgct ggattgggaa cttacccaga
     3301 ggtcagtatt gctgaagctg cacgtactgc ccggataatg cgagagcaac ttgctgcagg
     3361 tgatgatcct ctggagatta aaaaggctga atctgagaaa gtcgctatcc caacatttgc
     3421 cgatgcagcc aggcgtgtac atgcagaact gtctcctgga tgggaaaatc caaagcatgt
     3481 aaggcagtgg ttatcgacgc ttgagaatta cgcgtttcct caactgggag caaaaacgct
     3541 ggattcgatt acggctgcgg acgtggcaga aacactgcgt ccagtctggt taaccttgtc
     3601 agaaacggca agccgggtta aacagcgcat tcatgttgtt atgcagtggg gatgggcgca
     3661 cggtttttgt gtggcaaatc ctgttgatgt ggttgaccat ttgcttcctc agcagacaag
     3721 aggacgtgat gaacaccaac ccgcaatgcc ctggaggcag ttaccgcttt ttgtggcgac
     3781 cagtgtgtat accgatgaac cttataatgt tacccgcgca ctgttattaa tggtgatact
     3841 tacagcaact cgctcgggcg aagccagggg aatgcgctgg gctgaaattg attttcataa
     3901 gcgggtatgg actatacctg cagaaagaat gaaagccagg ctacagcatc gtgttccttt
     3961 atcccggcag gctatttaca ttctggaaaa tatacgtggc ctgcatgatg aactggtgtt
     4021 cccttcaccc agaaagcagc agatcctttc cgatatggtg ttgacaagtt ttctgcgtaa
     4081 aaagaaagcc gtcagtgaca ttccggggcg agttgccacg gcacatggtt ttcgctcaac
     4141 attcagggac tggtgtagtg aacaggggta ttcgcgggat ctggcggaaa gggcgctcgc
     4201 tcatacgctg aaaaataagg ttgaggcggc atatcatcgt actgatctac tggagcagcg
     4261 tgtaccgatg atgcaggcat gggcggatta tgtgatgtct caaattgtga ataaataata
     4321 gtgaaaatgt atattgtacg atcatgattt gatatgtgat cgtagcagta gtaattaagg
     4381 aaccgctttt atgtcaaatg tattgagctg ataattatca gatcgtcagg aaagcgtatt
     4441 tttataaaca ggggattact caacaatctc ctgtttataa aaaacaattt gcctgtttta
     4501 acgtttcact cctgctgaga ctgaattatt cctagtgcgt cataaatcag tcttctgcgt
     4561 agtttattgt ttttatctgc accatataac ataaatatat tttcaacttt ttcttcaggt
     4621 gttctgagat aatggataag aaaggttatc attccaacac aatggaataa agtgaatcca
     4681 tcaaacaggc ttatcaggtt tccttttttt tcccgtgttg taagtatttt ttcgcgggta
     4741 agaatatttg ccagttcatg gggggctgat atgtttctgc tgtctataat gttatttatt
     4801 ttaccaaggg ctatatcaac ttcctgtaat aggttattta tcatagctga gtgaatgtta
     4861 ttggtttcat gttcctgaca gtttatgaac ttataaatca ttgagttata cagaaatatt
     4921 actcttccta ataaatatgt gtttgtgtca ttttgaagac aggactctgg gtattcgtga
     4981 tccagtgaaa taaggtt
//
LOCUS       DAZUDJ010000163         4992 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.166, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000163 DAZUDJ010000000
VERSION     DAZUDJ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4992
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.166"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..170
                     /locus_tag="ACHY1N_004973"
     CDS             <1..170
                     /locus_tag="ACHY1N_004973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFS4047117.1"
                     /translation="HGGERGALLYSLIGTCKLNDVDPESYLRHVPGVIADWPVNRVSE
                     LLPWRIALPAE"
     gene            613..4515
                     /gene="espP"
                     /locus_tag="ACHY1N_004974"
     CDS             613..4515
                     /gene="espP"
                     /locus_tag="ACHY1N_004974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease autotransporter EspP"
                     /protein_id="HFS4047118.1"
                     /translation="MNKIYSLKYSHITGGLIAVSELSGRVSSRATGKKKHKRILALCF
                     LGLLQSSYSFASQMDISNFYIRDYMDFAQNKGIFQAGATNIEIVKKDGSTLKLPEVPF
                     PDFSPVANKGSTTSIGGAYSITATHNTKNHHSVATQNWGNSTYKQTDWNTSHPDFAVS
                     RLDKFVVETRGATEGADISLSKQQALERYGVNYKGEKKLIAFRAGSGVVSVKKNGRIT
                     PFNEVSYKPEMLNGSFVHIDDWSGWLILTNNQFDEFNNIASQGDSGSALFVYDNQKKK
                     WVVAGTVWGIYNYANGKNHAAYSKWNQTTIDNLKNKYSYNVDMSGAQVATIENGKLTG
                     TGSDTTDIKNKDLIFTGGGDILLKSSFDNGAGGLVFNDKKTYRVNGDDFTFKGAGVDT
                     RNGSTVEWNIRYDNKDNLHKIGDGTLDVRKTQNTNLKTGEGLVILGAEKTFNNIYITS
                     GDGTVRLNAENALSGGEYNGIFFAKNGGTLDLNGYNQSFNKIAATDSGAVITNTSTKK
                     SILSLNNTADYIYHGNINGNLDVLQHHETKKENRRLILDGGVDTTNDISLRNTQLSMQ
                     GHATEHAIYRDGAFSCSLPAPMRFLCGSDYVAGMQNTEADAVKQNGNAYKTNNAVSDL
                     SQPDWETGTFRFGTLHLENSDFSVGRNANVIGDIQASKSNITIGDTTAYIDLHAGKNI
                     TGDGFGFRQNIVRGNSQGETLFTGGITAEDSTIVIKDKAKALFSNYVYLLNTKATIEN
                     GADVTTQSGMFSTSDISISGNLSMTGNPDKDNKFEPSIYLNDASYLLTDDSARLVAKN
                     KASVVGDIHSTKSASIMFGHDESDLSQLSDRTSKGLALGLLGGFDVSYRGSVNAPSAS
                     ATMNNTWWQLTGDSALKTLKSTNSMVYFTDSANNKKFHTLTVDELATSNSAYAMRTNL
                     SESDKLEVKKHLSGENNILLVDFLQKPTPEKQLNIELVSAPKDTNENVFKASKQTIGF
                     SDVTPVITTRETDDKITWSLTGYNTVANKEATRNAAALFSVDYKAFLNEVNNLNKRMG
                     DLRDINGEAGAWARIMSGTGSASGGFSDNYTHVQVGVDKKHELDGLDLFTGFTVTHTD
                     SSASADVFSGKTKSVGAGLYASAMFDSGAYIDLIGKYVHHDNEYTATFAGLGTRDYST
                     HSWYAGAEAGYRYHVTEDAWIEPQAELVYGSVSGKQFAWKDQGMHLSMKDKDYNPLIG
                     RTGVDVGKSFSGKDWKVTARAGLGYQFDLLANGETVLRDASGEKRIKGEKDSRMLMSV
                     GLNAEIRDNVRFGLEFEKSAFGKYNVDNAVNANFRYSF"
     gene            complement(4763..>4992)
                     /locus_tag="ACHY1N_004975"
     CDS             complement(4763..>4992)
                     /locus_tag="ACHY1N_004975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047119.1"
                     /translation="AQNQPAETVRAAAAATGRFAVAFPVRVAPGSGCFMKTNAPRLFF
                     VDKEAGVSFDVFHVLSVSFPVTACATHDGGM"
BASE COUNT         1514 a         1135 c         1113 g         1230 t
ORIGIN      
        1 accatggtgg tgagcgggga gcgctactgt acagcctgat cgggacgtgc aaactgaatg
       61 acgtggatcc agaaagctac cttcgccatg tgcctggcgt catagcagac tggccggtca
      121 accgggtcag cgaactgctt ccgtggcgca tagcactgcc agctgaataa cacatccccg
      181 tcaatacggc cctcgctgta cgcttacgca taaatattga atacatttac tgagcatgca
      241 aaagaaaaag acaaactaat cccggccttt cacagaattt cctctatcag aggctgagtt
      301 gacaacctgc tcacccagga aatagtaacc cccgaaaaca tgaagagact ctgataaaca
      361 atctcgatac atattcctca tctttcacag catctcactt ctttaacagg aattattatt
      421 atctacgcct cctcctttca tgtatccctc atgaatgatt aagataaaca tactgtgttt
      481 gttatccgta tgataacaaa cacataaagg agtaaacatt tatctggatg atgattacaa
      541 tgttcacgac tgtcagagac acacctctga tacattagaa aaaccaatgt ttcccttaaa
      601 aatggagctt atatgaataa aatatactct cttaaataca gccatattac aggagggtta
      661 atcgctgttt ctgaattatc cggcagagta tcatcaagag caactggtaa gaaaaaacac
      721 aaacgcatac ttgcattatg ttttttaggc ttattacaat cctcatattc ttttgcgtca
      781 cagatggata tttcaaattt ctacatccgt gactatatgg attttgcaca gaacaagggc
      841 atatttcagg ctggcgcaac aaatattgaa atagtgaaga aagatggctc caccctgaaa
      901 ctaccggaag taccatttcc tgacttctca ccggttgcaa acaaagggtc aaccacatct
      961 attggtggtg catacagtat cacagccaca cacaatacga aaaaccacca ctcagttgcg
     1021 acgcaaaact gggggaacag cacgtacaaa caaactgact ggaatacttc acatcctgat
     1081 tttgcagtat cccgacttga caagtttgtt gttgagaccc gaggtgcgac tgaaggcgca
     1141 gatatttcgt tatcaaaaca gcaggcactt gaacgttacg gggttaatta taaaggagaa
     1201 aagaaactta tcgcattcag agccggctct ggtgtggtat ccgttaaaaa aaatggacgc
     1261 ataactccat ttaatgaggt ttcttataag ccagaaatgt taaatggctc tttcgttcac
     1321 attgatgact ggagtggatg gctgatatta accaacaacc agtttgatga gtttaataac
     1381 attgcctctc agggtgacag cggttcagca ctgttcgtct atgataacca aaagaaaaag
     1441 tgggttgtcg ctggaactgt ctgggggatt tataattacg ccaatggcaa aaaccacgca
     1501 gcatacagta aatggaacca gacaaccatt gacaacctga agaacaagta ttcttacaac
     1561 gtggatatgt caggagctca ggttgcaacc attgaaaatg gaaaactgac aggcactggc
     1621 tcagacacca ccgatataaa aaataaggac ttaatattta ctggcggtgg agatatcctc
     1681 ctgaaatcct cttttgataa tggtgctggc ggtcttgtct ttaatgataa aaagacctat
     1741 cgagtaaacg gggatgattt cacctttaaa ggtgccggtg ttgatacaag aaacggcagc
     1801 accgttgagt ggaatatccg gtatgataat aaagacaacc ttcacaaaat tggtgatggc
     1861 acattagatg tccgaaaaac ccagaacacc aacctgaaaa caggtgaggg tcttgtcatt
     1921 cttggagctg aaaaaacatt caataatatc tacataacca gtggtgatgg aactgtccga
     1981 ctgaatgcag aaaatgcact gtctggcggt gaatacaacg gtattttctt tgcgaaaaat
     2041 ggcggaactc ttgacctgaa cggatataat cagtctttca ataaaattgc tgcaactgat
     2101 tcaggtgctg taataaccaa tacgtcaacc aaaaaatcca ttttatccct gaataatact
     2161 gctgactata tctatcacgg caacataaac gggaatctgg acgtacttca gcatcatgag
     2221 acgaaaaaag agaaccgtcg tcttattctt gatgggggcg tggacacaac aaatgatata
     2281 agcctgcgta atacacaact gtccatgcag ggacatgcca ctgaacatgc catttatcgg
     2341 gatggagctt tctcttgttc actaccagct cctatgcgct ttttgtgtgg cagtgattat
     2401 gttgcaggaa tgcaaaatac agaagctgat gctgtaaaac aaaacggaaa tgcctataaa
     2461 accaacaatg ctgtctctga tttatcgcag ccagactggg aaaccggaac attcagattt
     2521 ggaacgctac atcttgaaaa ttccgatttt tctgttggtc gtaatgcaaa tgtaatcggg
     2581 gacattcagg ccagtaaatc aaacattact attggtgaca ctacagcata tattgatttg
     2641 catgctggta aaaatattac cggtgatggt tttggcttcc gccagaatat tgtgcgtgga
     2701 aactcacaag gagaaacgct gtttacagga gggatcacag cagaagacag cactatcgtt
     2761 attaaagata aagcaaaagc attattttca aattatgtat acctgctgaa cacaaaagca
     2821 accatagaga acggtgctga tgtgacaact caaagtggta tgttctccac gagcgatatc
     2881 agcatctctg gtaatctgtc catgacaggc aatcccgaca aagacaataa attcgagccc
     2941 tcaatatatc tgaatgatgc ttcttatcta ctgactgacg actccgccag actcgttgcc
     3001 aaaaataaag catctgtggt gggagatata cactccacta aaagtgcatc catcatgttt
     3061 ggtcatgatg aaagcgacct ctcgcagttg tctgacagaa cctcaaaagg gcttgcactt
     3121 ggtcttttag gtggctttga tgtctcatat cgcggttcag tcaatgcccc gtcagcatct
     3181 gccactatga acaatacctg gtggcaacta accggagatt ctgcgctgaa aacactgaaa
     3241 agtacaaaca gcatggtcta tttcactgac agcgcaaaca ataagaaatt ccatacgctg
     3301 acggtcgatg agctggcaac cagcaacagc gcctatgcga tgcgtacaaa cctttctgaa
     3361 tcagacaaac tggaggtcaa aaaacacctg tctggtgaga acaatatttt actcgttgat
     3421 ttccttcaga aaccaacgcc tgaaaaacaa ctgaatattg aactggtaag cgcgccaaaa
     3481 gacaccaatg aaaatgtctt taaagccagt aaacaaacca ttggtttcag tgatgtaacg
     3541 ccggtcatta caaccaggga aaccgatgac aaaataacat ggtcactgac aggctataac
     3601 acggtagcaa acaaggaagc aacccggaat gccgccgccc tgttctctgt tgactataaa
     3661 gcgtttctga acgaggtcaa caacctgaac aaacgtatgg gtgacctgcg tgatatcaac
     3721 ggcgaagccg gtgcatgggc acgcatcatg agcggtaccg gctctgccag tggtggtttc
     3781 agtgacaact acacgcacgt tcaggtcggg gtcgacaaaa aacacgagct ggacggactg
     3841 gatttgttta ccggtttcac tgtcacacac actgacagca gtgcctccgc cgatgttttc
     3901 agtggtaaaa cgaagtctgt gggggctggc ctgtatgctt ccgccatgtt tgattccggt
     3961 gcctatatcg acctgattgg caagtatgtt caccatgata atgagtacac tgcaaccttt
     4021 gccggactcg gaacccgtga ttacagcacg cattcatggt atgccggtgc agaagcgggc
     4081 taccgctatc atgtcactga ggatgcctgg attgagccac aggctgagct ggtttacggt
     4141 tctgtatccg gtaaacagtt tgcatggaag gaccagggaa tgcatctgtc catgaaggac
     4201 aaggactaca atccgctgat tggccgaacg ggtgtggatg tgggtaaatc cttctctggt
     4261 aaggactgga aagtgacagc ccgtgccggt ctgggctacc agttcgacct gctggctaac
     4321 ggcgaaaccg tattgcggga tgcatctggt gaaaaacgca tcaaaggtga aaaggacagc
     4381 cgtatgctga tgtccgttgg cctgaatgca gaaatcaggg ataacgtccg ctttggactg
     4441 gagtttgaga aatccgcctt tggtaagtac aacgttgata atgcagtcaa cgctaatttc
     4501 cgttactcgt tctgatactc cgtattcaaa agggcctgcg ggccctttac gctcagtgcc
     4561 tgccgccctg atatgtctga gagacatttc cgggatgtca gtcgactggt ttacttaact
     4621 gcgatgacta aagctggcag taatgccggc ttttttacgg ccacatacgt cttcctctca
     4681 tccggaactg tgatacaaat cctgcataca ggattgaccg ccggttcctg caaatggcac
     4741 attttcagta agatagcgaa ggttacattc ccccgtcatg tgtggcacaa gctgtcaccg
     4801 ggaaagaaac ggaaagcaca tgaaaaacat caaaactcac accggcctcc ttatccacaa
     4861 agaacaaacg cggcgcgttc gtcttcatga aacacccact gcctggtgcc acacgcaccg
     4921 ggaatgctac agcaaaacga ccggtcgccg ctgcggcagc cctgacagtc tcagcaggct
     4981 gattctgagc ag
//
LOCUS       DAZUDJ010000164         4893 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.167, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000164 DAZUDJ010000000
VERSION     DAZUDJ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4893
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.167"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            155..1129
                     /gene="hemB"
                     /locus_tag="ACHY1N_004976"
     CDS             155..1129
                     /gene="hemB"
                     /locus_tag="ACHY1N_004976"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HFS4047120.1"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
     gene            complement(1235..2086)
                     /gene="tauD"
                     /locus_tag="ACHY1N_004977"
     CDS             complement(1235..2086)
                     /gene="tauD"
                     /locus_tag="ACHY1N_004977"
                     /EC_number="1.14.11.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="HFS4047121.1"
                     /translation="MSERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQV
                     VFLRDQTITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEEEHQRWREAVAKNPPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKES
                     EALLGFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     KPFYRAG"
     gene            complement(2083..2910)
                     /gene="tauC"
                     /locus_tag="ACHY1N_004978"
     CDS             complement(2083..2910)
                     /gene="tauC"
                     /locus_tag="ACHY1N_004978"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015411 - ABC-type taurine transporter
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter permease TauC"
                     /protein_id="HFS4047122.1"
                     /translation="MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVAAL
                     QLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVVIGIPVG
                     IAMGLSPTVRGILDPVIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
                     ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     gene            complement(2907..3674)
                     /gene="tauB"
                     /locus_tag="ACHY1N_004979"
     CDS             complement(2907..3674)
                     /gene="tauB"
                     /locus_tag="ACHY1N_004979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015411 - ABC-type taurine transporter
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter ATP-binding subunit"
                     /protein_id="HFS4047123.1"
                     /translation="MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLL
                     NLIAGFVPYQHGSILLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEK
                     MQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
                     AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLPLNFA
                     RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
     gene            complement(3687..4649)
                     /gene="tauA"
                     /locus_tag="ACHY1N_004980"
     CDS             complement(3687..4649)
                     /gene="tauA"
                     /locus_tag="ACHY1N_004980"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015411 - ABC-type taurine transporter
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4047124.1"
                     /translation="MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGASVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDYAEKHP
                     EVVKAFAKSAIDAQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
                     QQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
BASE COUNT         1130 a         1410 c         1246 g         1107 t
ORIGIN      
        1 tcagtgaata tgaaattatt gctatttcta ttacaaagat gtcctggtct ctctttcatt
       61 ctcttcttgt caacatcacg acaactttcg taaaacactc ctgccccgct tcaggtatac
      121 tgtgcacctt aattccacaa acatcaggca gaccatgaca gacttaatcc aacgccctcg
      181 tcgcctgcgc aaatctcctg cgctgcgcgc tatgtttgaa gagacaacac ttagccttaa
      241 cgacctggtg ttgccgatct ttgttgaaga agaaattgac gactacaaag ccgttgaagc
      301 catgccaggc gtgatgcgca ttccagagaa acatctggca cgcgaaattg aacgcatcgc
      361 caacgccggt atccgttccg taatgacttt tggcatctct caccataccg atgaaaccgg
      421 cagcgacgcc tggcgggaag atggactggt ggcgcgtatg tcgcgcatct gcaagcagac
      481 tgtgccagaa atgatcgtca tgtcagacac ttgtttctgt gaatacactt ctcacggtca
      541 ctgcggtgtg ctgtgcgagc atggcgtcga caacgacgca actctggaaa atttaggcaa
      601 gcaagccgtg gttgcagctg ctgcaggcgc agacttcatc gccccttccg ccgcgatgga
      661 cggccaggta caggcgattc gccaggcgct ggacgctgcg ggatttaaag atacggcgat
      721 tatgtcgtat tcgaccaagt tcgcctcctc cttttatggc ccgttccgtg aagctgccgg
      781 aagcgcatta aaaggcgacc gcaaaagcta tcagatgaac ccaatgaacc gtcgcgaggc
      841 gattcgtgaa tcactgctgg atgaagccca gggcgcagac tgcctgatgg ttaaacctgc
      901 tggagcatac ctcgacatcg tgcgtgagct gcgtgaacgt actgaattgc cgattggcgc
      961 gtatcaggtg agcggtgagt acgcgatgat taagttcgcc gcgctggcgg gtgctataga
     1021 tgaagagaaa gtcgtgctcg aaagcttagg ttcgattaag cgtgcgggtg cggatctgat
     1081 tttcagctac tttgcgctgg atttggctga gaagaagatt ctgcgttaat ttttttcctc
     1141 tcagaaaggg ggagttaacc tgttgaaagt acggtgaacg ccccctcacc ctaaccctct
     1201 ccccaagggg gcgagggaac cgtccgcact cgtatcaccc cgcccgataa aacggtttat
     1261 ccccaaggat cgtcgcccga tgcataatcc gccgctgtgg caggtaatcg gcattggcat
     1321 agtgctgagt cacgcggtta tcccaaatcg caatatcatt cggttgccag cgccaacgca
     1381 cctgaaactc cggtttagtg atatgggcga ataaaaagcc taacaaggct tcgctctctt
     1441 tctcgctgac atcgacaatt cgcgtagtaa agccttcatt cacaaacagc gcctgtttac
     1501 cgctcaccgg atgcgttcgc accaccggat gtagcaacgg aggatttttc gcgaccgcct
     1561 cgcgccagcg ttgatgttcc tcctcggttt tgcggtattt gtattccggg aacgatttac
     1621 ggaaatcatg ctccgcacgc agcccgctca gcagctggcg gaagggaaca gagagcgcct
     1681 cataggccgc aataccgctg gtccagagcg tatcaccgcc ggtcgaaggt aactctttag
     1741 ctgccagaat cgcccctgcg ggtggcgttt caataaatgt cacatcggta tgccagttgt
     1801 cgttatccgg cggattatcg ttatgggtat ccagcacgat gatctcgtca accccttcgg
     1861 catgagggta aacagggtga atatgcagtt cgccaaaacg ctgggccagc gcgcgttgct
     1921 gctgcggcgt aatagtttga tcgcgcagaa acaccacctg atggcgcagc accgcatggt
     1981 aaagctgttc aaactgatta tcgcttaacg ggcgcgtcag gtcggcaccc gaaatttgtg
     2041 cgccgatata cggccccagc ggggtaatgc tcagacgttc actcattgta cttctccatg
     2101 ccagggcgtc agacggcgct gtaacgcgcg caaacccagt tctaaaagaa aggcgataat
     2161 cgcaatcacc gcgattcccg ccagcaccac gtcagtcgcg agaaattcac ccgctgactg
     2221 aaccataaat cctaaaccgc gcgtcgcggc aatcagctcc gccgctacca gcgtagacca
     2281 gcccacaccc agaccaatgc gtaatccggt gaggatttcc ggcagcgcgc cgggcaaaat
     2341 gacaaaccac agcacctgcg cacggctggc acccagcgac tgggcggcac gaatgcgaac
     2401 ctgctgcgcg cttttcaccc ccgccagcgc cgacatcgcc accggtgcaa aaatcgctaa
     2461 atagatcagt aagatcttcg aggtttcacc aataccaaac cagatcacca tcagcggcaa
     2521 ataagccagc ggcggcacgg gacgataaag ttcgattacc ggatccagaa tgccgcgcac
     2581 cgtcgggctt agccccatgg cgatcccgac cggaataccg atcaccaccg ccgcgagtag
     2641 cgccagcaca atgcgcgtca ggctggctgc cagatgctgc cacagcgtgg cgtccataaa
     2701 tccctgcggt ccggcaatgg tgagcagttt tgccagtact tgttgcggcg gcggcaaaaa
     2761 cagcgggcta atcagttgca gcgccgccac cgtccaccat acagtgagta aaaccgctaa
     2821 cgtgccaatg cttaaggtca cctgacgcga gagcggccag cgccatttca gccgccgcga
     2881 atgcagtttt tcattaatga gcacactcat gagaacgcct cccgttgctc aaatacgcgg
     2941 cttaaaacat attcgcgcat ggcgatgaat tgtggatcgg acttgatgct gcggctcgac
     3001 tctcccgcaa caaagcggcg agcaaagttg agcggcagcc gctccagcac acggccaggg
     3061 ccggatgaaa gcagaaccag ttcagtcgcc ataaacaccg cttcttctat atcgtgggta
     3121 atcaacagca cctgcttgcc cgtctcctgc cagagtttca gcagcagagt ttgcatctgg
     3181 tcgcgggtga aggcgtccag cgcaccaaac ggttcgtcga gtaataacag ctggggattc
     3241 gccgccagcg cgcgggcaat ccccacccgc tgacgttgac caccggaaag ctgccagatg
     3301 tagcgttttt ctgcgccttc cagccccact tttttcagca tctggtgcgc gatttccagt
     3361 cgctgcattt tctctatacc tgccaattgc aggccgaacg ccacgttgtc ctgtacattg
     3421 cgccacggta gtagcccttc attctgaaaa actacgccac gctctgctcc cggtccctca
     3481 atacgcttac ccgccagtag aatgctgcca tgctgataag gcacaaaacc ggcaatcaga
     3541 ttcagcaacg tggttttacc gcagccggac ggccccagca ccaccagtag ctcgccgctt
     3601 tccagcgtca ggttgatatc ttccagtgcc ggtttgccgc cataatcggc gtaaagatga
     3661 gagatttgca gcatctgcgc ctccttttat tgcacgaagc gcgaggtaac gtactggctg
     3721 taatcattcg ctacagccgg gaccttgccc tgctctttca aaaactgcgc ggtgtcgatg
     3781 atcgctttgt tcaccggtcc ggtcagttct gccgtttgtt gctgcggcgt cagataggta
     3841 ttccccttca ccagccccgg aacgtcacct tcaggcacgc cgcttaaacg cgccagtttg
     3901 ctgatgtttt ccggctgttt cagccacacg tctgggttag caatgtacgg ttgctgagca
     3961 tcgatggcgc ttttagcgaa cgctttcacg acctcaggat gtttctcggc ataatctttg
     4021 cgcaccaccc agacgtccag cgttggcgcg ccccactgcc cgacctgttc agaatcggtc
     4081 aacaccttgc cgtctttttc cagggcgtta accgccggtg cccagacata agcaccatca
     4141 atatctcccc gctgccaggc agcgataatc gcgggcggct gcaggttcac aatctccact
     4201 tgcccgggtt taatgcccca gtgtttcagc gccgccagca ggctgtagtg ggtggtggag
     4261 ataaacggta cggcgatgcg tttgccaatc agatcttccg gtttgctgat agttttcttt
     4321 accaccagcg cttcggagtt acccagtttt gacgccagca agaagacttc aatcggcacc
     4381 tgttggctgg ctgcaaccgc taacgggctg gaaccgaggt tgccgatttg cacatcgcct
     4441 gaagccagcg cccgcacgat gctggctccg ctgtcaaact tacgccagtc cacgctcgcc
     4501 ccgctctctt tagcaaaggt gttgtcggcc tgagccactt tcgccggttc ggctgaggtt
     4561 tgataggcca cggtgacgtt caccgcctgt gcctgaaaag cgatgaatgc cagtgcggct
     4621 agaagtgtgt tacgcgatga aattgccatg attgtctgct cccctgtctt gttatgggag
     4681 cagtattcag gaataaaaac attcattaaa agaattagtc gttatcgcac agatgatttt
     4741 attcttagca aaaaaacggc taaggaaaga ttaaatatgc aattactccg ttctaacaat
     4801 tgggaaaatt actacacttc attttagtga tgcataaaca accacattac gagatttatt
     4861 gcttcattat ttctatcaat atcaatacat ata
//
LOCUS       DAZUDJ010000165         4866 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.168, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000165 DAZUDJ010000000
VERSION     DAZUDJ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4866
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.168"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..338)
                     /gene="xdhC"
                     /locus_tag="ACHY1N_004981"
     CDS             complement(<1..338)
                     /gene="xdhC"
                     /locus_tag="ACHY1N_004981"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase iron sulfur-binding
                     subunit XdhC"
                     /protein_id="HFS4047125.1"
                     /translation="MNHSETITIECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGC
                     CVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGAVQ
                     CGFCTPGLIMA"
     gene            complement(335..1213)
                     /gene="xdhB"
                     /locus_tag="ACHY1N_004982"
     CDS             complement(335..1213)
                     /gene="xdhB"
                     /locus_tag="ACHY1N_004982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase FAD-binding subunit XdhB"
                     /protein_id="HFS4047126.1"
                     /translation="MFDFASYHRAATLADAINLLADNPQAKLLAGGTDVLIQLHHHND
                     RYRHIVDIHNLAELRGITLAEDGSLRIGSATTFTQLIEDPITQRHLPALCAAATSIAG
                     PQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTGPGKVSL
                     EHDEILVAFHFPPQPKEHAGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFG
                     VAAPTPIRCQHAEQTAQNAPLNLQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMT
                     KKVISEAVAAAGGKLQ"
     gene            complement(1224..3521)
                     /gene="xdhA"
                     /locus_tag="ACHY1N_004983"
     CDS             complement(1224..3521)
                     /gene="xdhA"
                     /locus_tag="ACHY1N_004983"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdenum-binding
                     subunit XdhA"
                     /protein_id="HFS4047127.1"
                     /translation="MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVR
                     SPIAHGYAVSINDEQARSLPGVLAIFTWEDVPDIPFATAGHAWTLDENKRDTADRALL
                     TRHVRHHGDAVAIVVARDELTAEKAAQLVSIEWQELPVITTPEAALAEDAAPIHNGGN
                     LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSST
                     QIPHIVRRVVGQALDIPWSCVRVIKPFVGGGFGNKQDVLEEPMAAFLTSKLGGIPVKV
                     SLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAGGN
                     KVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEI
                     RLRNAAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQQGNLRRGVGVA
                     CFSYTSNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFSQMVAETVGVPVS
                     DVRVISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLHQSAMNL
                     TLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVD
                     LTVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGV
                     VRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKSLGEPPIIPVAAAIRNAVKMA
                     TGVAINTLPLTPKRLYEEFHLAGLI"
     gene            3936..4691
                     /gene="actS"
                     /locus_tag="ACHY1N_004984"
     CDS             3936..4691
                     /gene="actS"
                     /locus_tag="ACHY1N_004984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311765.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase activator ActS"
                     /protein_id="HFS4047128.1"
                     /translation="MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTV
                     KRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSSTRKSTAKSTT
                     KTASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYA
                     AGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGST
                     DAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            4770..4843
                     /locus_tag="ACHY1N_004985"
     tRNA            4770..4843
                     /locus_tag="ACHY1N_004985"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4802..4804,aa:Gly,seq:ccc)
BASE COUNT         1177 a         1225 c         1291 g         1173 t
ORIGIN      
        1 gccataatca ggccaggcgt acaaaacccg cactgcactg cgccggattt cgcataagcc
       61 tgctgaacat gagaaagttt tccgcctttc gcttcacctt ccagcgtgcg gatctctttt
      121 ccttcagccc aggcggcaag gtataagcaa ctgtctattg ctgtgccgtc gaccagcacc
      181 gtacaggcac cacattcacc cacgcagcac ccttgtttga cacttagcag tccttgttcg
      241 cggagtaatt ccgagagcgg cgtgcctggt gcggcgtgaa gctgaaaagg catcccgtta
      301 atggtgcatt cgatggtaat tgtttcgctg tgattcattg caattttccc cccgccgcgg
      361 cgacggcttc gctaatcact tttttggtca tcgtctggat gagatgcaga cgaaactctt
      421 tactggcccg ccatgaagaa cgcggggcga catcttgcag gacagattcg ctgatagctt
      481 ccagcgtttg caggtttaat ggcgcatttt gtgcagtctg ttcggcatgt tggcagcgaa
      541 tcggcgttgg cgcggcaaca ccaaatgcca ggcgtaattc gctgaaattg ccgttatcca
      601 gtcggcaatg tgcggcgcag ccaatcgttg aaatatccat tgcgtcgcgc atggcatatt
      661 taaaatgcgc gctgcccgcg tgttctttcg gctgtggcgg aaaatgaaag gcgacgagga
      721 tttcgtcatg ctcaagagac actttgcccg gcccggtgtg aaagccatta atcgggacga
      781 aacgaacacc gcgcggggag tggatctcca gtttcgcgtc ataaattagc gttggcgtgg
      841 cagaatctgc gctggtggca ccgttgcaaa tatttccacc gtaggtagcg acgttacgga
      901 tctgcggtcc agcaatggac gtggccgcag cacataacgc cgggagatga cgttgagtta
      961 taggatcttc tattagctgg gtaaatgtcg ttgcagagcc gatacgtagc gagccatctt
     1021 ccgccagcgt aattccccgc agctccgcca gattatgaat atcaacaata tggcgataac
     1081 ggtcattgtg atggtggagc tgaatcagta cgtcagtgcc accggcgagc agtttggcct
     1141 gcgggttgtc agccagcagg ttgatggcat cggcaagggt tgctgcgcga tggtaagaag
     1201 caaaatcaaa catgatgtta tcctcaaatc aatcctgcca gatggaactc ttcatataac
     1261 cgttttggcg tcagcggcag tgtattgatt gcaacaccgg tagccatctt caccgcgtta
     1321 cgaatagcag cggcaacagg aattattggt ggctcaccca gtgacttatg tccgtatgcg
     1381 gattgcggct cattgatttc gacgaacgcg ctttccagtt gtggcagatc cggcatggtc
     1441 ggcattttgt aatccagcag attggggtta cggaccacgc cgcttttagc atcgatgatc
     1501 atctcttcaa atagcgccca gccaatgccc attcccattc cgccgtgtac ctgaccttct
     1561 gccagcagtg gattaagaat atgccctgaa tcatgaacgt tgaggatgcg gttgatggtg
     1621 actttgcaca gcgcaatatc gaccgtcaga tcaacaaagg tacagccaaa cgccggtggg
     1681 ttagtggtgg ttttgatgga gctttcagca gagagctgcc cgccgcgttc agggtggtag
     1741 aaagcgtcca tcgccaaatc ttttaacgac attaacggct cttccggtcg ttcaaccagc
     1801 acgatatggc cttttatcag ggtcagattc atcgctgact gatgtagcat gactgcggcg
     1861 tgagcgatga ttttctcttt taataatagt gccgcactgc gcagcgcagg cgcggcaaca
     1921 tagctctggc gtgaggcaaa tgcgccggga tcgaacggcg taacgtcggt atcttgagtt
     1981 gaaataacgc gaacgtcgct gaccggaacc cccacggttt ctgccaccat ttgcgagaag
     2041 acggtgtcgg caccctgacc gatttccgtc gcgccgcttt gcacgttgat ggttccatcc
     2101 tgattcatca gaaggcgcgc gcctgctatt tctacgccga caggccaggt gttagaggtg
     2161 tagctaaaac aggcgacgcc aacgccgcgg cgcaaattgc cttgctggtt ctggcattct
     2221 gcacggcgtt tttcccattc aaagattttc cggccttttt caagacactc cggcaaccct
     2281 gcgctgtaaa tacgtttgcc cgtgagcgga ttagcatctc cttcgcgggc ggcgttgcgt
     2341 aaacgaattt caacaggatc aatacctaac gctgtcgcgg cgtcatcaag catagactca
     2401 acggcaaata cgacttgtgg cgcgccataa ccacgcatcg caccagccga ggggaggttg
     2461 gtatagcagg tctttgaact gtaagcgtag gcacaacgag gataaaggta agcgacttta
     2521 ttcccccccg cagaagcgat ggagtgcccg tgagatgcat aagcgccggt gttagacaga
     2581 acatccagac tataaccttt caatgttccg tcgcggttca cgcccatttg cccgtcaatg
     2641 gtaaaagcgt ggcgggtacg ggttgcgagg aaacactctt cacggctaag ggaaactttc
     2701 accggaatgc cgccaagctt gctggtcagg aatgccgcca ttggctcttc cagtacatcc
     2761 tgtttattac caaaaccgcc accgacaaac ggtttgatga ctcgtacgca tgaccaggga
     2821 atatccagcg cctgaccaac cacgcggcga acaatgtgcg ggatctgggt gctggaaacg
     2881 atggtaattc gcgagtcatc ctccatccac gccagcgatg ttacgctttc catgtgacaa
     2941 tgttgaataa cgggggtctg atagtgcccc tgtacctggt agtcggcggc atcgattgtt
     3001 tgttggacat tacccgtcga catcgtgctt tgtttcagta aattgccacc gttatggatt
     3061 ggtgcagcgt cttctgccag cgccgcttct ggcgtggtga taacgggtaa ttcttgccac
     3121 tcaatgctga ccaattgcgc cgctttttct gccgtgagtt catcgcgggc cacgacgatg
     3181 gcaacggcgt caccatgatg acgaacatgg cgagttagca gtgcgcgatc ggcggtatcg
     3241 cgcttgtttt cgtcaagtgt ccaggcatgc ccagcagtag caaatggaat atcaggcaca
     3301 tcttcccagg taaaaatcgc cagtacgccc ggcaaacttc tggcttgttc atcattaata
     3361 cttacggcat aaccatgtgc gatagggcta cgtacatatt tcgcataaca catgcccgcc
     3421 ataacataat cgtcagtata tcgtgcccgc ccggtgacct tagcaatggc atcgacgcgc
     3481 atgcatgatt cacccgtagc ggttgcttcc cgcgcttcca tagaaatccc ctcgatttga
     3541 acatttggtt cttatggcaa agatttagtc taagcaggca agatttacgc cagaaacgac
     3601 gataagcgtt aggggaggta ggaagtgtga tgacgttaaa aaaacacaga tatgatacga
     3661 aacaggactc tgaatagggg cagtgatacg tatcaatatg agtggcgata aaatcaatgt
     3721 gataaattgg gattattacg catcaggatg ggaaataggg taaaaagtca ggaagttcga
     3781 tacctctaca gcgaatattt tgctgatgat acttcccttt gccaaatgaa attaacctct
     3841 ttctctatta ccacgttttt ccagaagcaa gagattgggt atcaagaggc tggctgctat
     3901 gataaggcgt cttgtttttt aagcgaggaa agattttgag tgcgggacgc ctgaataaaa
     3961 aatctctggg tatcgtgatg ttgttatcgg ttggactgct tttggcgggc tgttcgggta
     4021 gcaaatcatc cgatacagga acgtattccg gctccgttta caccgtgaaa cggggggata
     4081 cgctatatcg tatttcgcgc accacgggaa ccagcgtaaa agaactggcg cgactgaacg
     4141 gcatttcccc cccttacacc attgaagttg gtcagaaact aaaactgggt ggggcgaaaa
     4201 gtagcagtag tacacgtaaa tcaaccgcca aatcaacgac caaaaccgca tcggttacac
     4261 cgtcatcagc ggtaccgaaa tcttcctggc cgccagtagg gcaacgttgt tggttatggc
     4321 caacgacagg gaaagttatc atgccgtatt cgacagcaga tggcggcaat aaagggattg
     4381 atatctcagc tccacggggc acacctattt acgccgcggg tgcaggaaag gtggtgtatg
     4441 tgggcaacca gctgcgtggc tacggtaatc tcatcatgat taaacacagt gaagattaca
     4501 ttacggctta cgcccataat gacacgatgc tggtaaataa tgggcaaagc gtgaaggctg
     4561 ggcaaaaaat cgccactatg gggagcacgg atgcggcatc tgttcgcctg catttccaga
     4621 ttcgttaccg tgcaacggca attgatccgc tacgttactt gccgccgcag ggcagcaagc
     4681 caaaatgctg atggcgaatt aatcagcagt cagcagcgcg gcacttgcta aggagagcgt
     4741 aaggtttata atgccttacg catctcgaag cgggcgtagt tcaatggtag aacgagagct
     4801 tcccaagctc tatacgaggg ttcgattccc ttcgcccgct ccaatttatc ttcacctgat
     4861 caatct
//
LOCUS       DAZUDJ010000166         4858 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.169, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000166 DAZUDJ010000000
VERSION     DAZUDJ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4858
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.169"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(679..2043)
                     /locus_tag="ACHY1N_004986"
     CDS             complement(679..2043)
                     /locus_tag="ACHY1N_004986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EspK/GogB family type III secretion system
                     effector"
                     /protein_id="HFS4047129.1"
                     /translation="MLSTSQLKLSGTACHHITETPASFKSEITSRQLEDARESGCLHI
                     KNCDMEFLPHLPEEITAITIENCNKLTGLTGLPVNIKSLSVINCENLKVSELPPTVRE
                     LHIELNNSSFVHTVPEGVEHLKLGHCQVSGVPDSVRSLELTGRAAETLTGVPSGLCSL
                     SIRDYNPEYQVRIDNFISPSLQTLSLTGCSNIVLPEKLPKGMVSATIYTEQKTTWNIV
                     AEGFPEEMDLDLQNVQLSPDVIKEKNITFQGYAMEAALHFRLGDIVYGLSEPRGKVVN
                     TIKLVNDFSKKDILIQNTLTSAVWDYKSPRKYKKDALIKRALSESDRGINFKQYLKNH
                     SQYNVTMADLSVCNRDKLWAKTSKAGLEFQLLVRNKMVHFCADGLVDTLKNIANKGDA
                     YGQSITASELRWIYRNQDNEQIMKNIKFYLRGKEVPAEKILGMPEWKDYHPKRSGLIS
                     EYSK"
     gene            complement(2334..2972)
                     /locus_tag="ACHY1N_004987"
     CDS             complement(2334..2972)
                     /locus_tag="ACHY1N_004987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1076 domain-containing protein"
                     /protein_id="HFS4047130.1"
                     /translation="MPVVLNISDGRALPESELEALRNIARSNQSDTLIVGSRSLRLHH
                     ISFMDAFSVEPIQGSLLDRLGGRCRRLAESLERQLNHGNTFLQAFSLYMEQVRLTPFW
                     LEGGRNAVQTRINSHAFTVNPGDFPCCEQHLSCPITLCIPKTGVFVKNALHSKVCSLY
                     DKDALSEAIRHNVFHPLSREAFSPEMIVGREECYFDLTDQRFCIISGQDVRF"
     gene            3170..3754
                     /locus_tag="ACHY1N_004988"
     CDS             3170..3754
                     /locus_tag="ACHY1N_004988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bfpT-regulated chaperone"
                     /protein_id="HFS4047131.1"
                     /translation="MPANISGTPFNSFGISFIQKQSCWRKSDDILRCSMGQRTIKLST
                     NTLNNRILTSVARQSTKDINAWKRDEQTVYPSRVINQGIDKYCAENSRNISSEVRQRV
                     FKFIEKDYSLKLNIIAAQSSINHLIIGNGRFGDKINMLCKGVSREVKNQTMDVIANQL
                     ADQFFQKHISPDVDIKQLRDDIPRYIMAASVISA"
     gene            complement(4000..4602)
                     /gene="espF"
                     /locus_tag="ACHY1N_004989"
     CDS             complement(4000..4602)
                     /gene="espF"
                     /locus_tag="ACHY1N_004989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE effector EspF"
                     /protein_id="HFS4047132.1"
                     /translation="MLNGISQAVSTLGRHITSAASRVSSAGLSGFSVSPQAVRLNPIR
                     AQSPFSPGTSNINARTTFNVSSPATSFTPSRPAPPPPTSGQASGASRPLPPIAQALKD
                     HLAAYEKSKSLEASGLKPARPAPPPPTSGQVSGSSRSLPPIAQALKDHLAAYEKSKSL
                     DTSSLKPSRPAPPPPTSGQASEASRPLPPIAQALKDKNRY"
BASE COUNT         1498 a         1100 c          890 g         1370 t
ORIGIN      
        1 cttctcgctt cttaccctta ccagaatcct ctgtcctcca cgagatcata aaatgatgta
       61 tcagaagtaa tacgacttga acagtacaaa atagtggtac atttggaatc gaagtgtaaa
      121 ggtaacttac tgttatttgg tgatttcatt gccgtgtcaa tgaatcctta attcgattcc
      181 gaatcaggca ccagactcat atcaacggac ctccatggag gtccgttttt catccataat
      241 cgccttcatt tgatgctgag ctgaacatat caacatcagg caacggcaca atctgtgtac
      301 aaactccgcc agccctcaga taacacatca ctgagtaaat ggtcaggtat tgcttatatt
      361 atgcccctct gcatctatta ttgctgccat ccactgagct tctgaggccg acaattttag
      421 ccgtggagct cgctcccccg caccaggtgg cttcatatca aaaccataag agcttctgga
      481 tataaccgtt ataccatcca cattacatgt tgttgatatc agttcacaat ttttagttga
      541 tggcttatca attattggat cagatatttc tggtcgacgt cctgtgtgac atgaaaaaca
      601 acttccgatt gacaatggca taattttatc tcctgccgat attactttac tgatatgcac
      661 tgtcataata gaagtgcatt atttagagta ttcagatatc aatccagaac gtttcggatg
      721 ataatctttc cattctggca tgcctaaaat tttctctgcc ggaacttctt tcccacgtag
      781 ataaaacttt atatttttca ttatctgctc attatcctga ttacgataaa tccatcgcaa
      841 ctcactggct gtaatacttt gcccataagc atccccctta ttggctatat tttttagagt
      901 atcgacaagc ccatcggcac aaaaatgcac cattttgttc cttactaata actgaaactc
      961 caggccagcc ttactggttt ttgcccataa cttgtcacga ttacacacag aaagatcggc
     1021 catagtgaca ttatattgac tatggttctt caaatactgc ttaaagttaa ttcctctatc
     1081 agactcactt aatgctctct tgataagagc gtctttctta tatttccgag gagatttata
     1141 atcccataca gcacttgtta acgtattctg tattaaaata tcttttttag aaaaatcatt
     1201 aaccagtttt attgtattaa caacttttcc tctgggttcc gaaagcccat acacaatatc
     1261 ccctagacga aaatgtaaag ccgcctccat ggcatagccc tgaaaagtaa tatttttttc
     1321 tttaatcaca tctggagaaa gctgtacatt ctgtaaatca agatccatct cttcgggaaa
     1381 tccttcagca acgatgttcc atgtcgtttt ctgctctgta taaatggttg ctgacaccat
     1441 cccttttggg agtttttccg gcaacacgat attactgcaa cccgtcagag acaacgtctg
     1501 cagtgaaggg gatataaaat tatcgattct gacctgatac tccgggttat aatcccggat
     1561 actcagagaa cacaaccctg atggtacgcc ggtaagcgtc tccgcagccc tacccgtcaa
     1621 ctcaagagac cggacactat caggcacacc cgatacctga cagtgaccaa gtttcaaatg
     1681 ctcaacgccc tctggaacag tatgtacaaa agacgaatta ttcaattcaa tatgtagctc
     1741 tcttactgtc ggcggcagtt cactgacttt cagattctca caattaataa cggacaggct
     1801 ttttatattg accggtagcc ctgtaagacc tgtcagctta ttacagttct ctattgttat
     1861 cgctgtgatt tcttccggta aatgaggcaa gaactccatg tcacaatttt ttatatgcag
     1921 acaaccactt tcccgtgcat cttccagttg ccgggacgta atttcacttt taaagcttgc
     1981 aggtgtttca gtaatatgat gacaggcagt ccctgacaat tttaattgtg atgtggaaag
     2041 catcaataaa ttccattttc agaaaataaa tcactataag gtaagcccca tccgaggagc
     2101 ttacctgaca aatttcatac agagagcctg tatccagggt ttcccgatgg cgaaaaggca
     2161 tcattacaga cgctatttca cgctggaaaa gcaagtacag ttactacatg ttcattccag
     2221 aataaaccca gcaatctgac ccggattcta acaaccagca aaataatgtt gtcaatcgaa
     2281 gacgaataaa aagcagcagt cagtacaact cagtctgtat taatatcccc cactcaaaaa
     2341 cgtacatcct gcccggaaat gatgcagaaa cgctgatcag ttagatcaaa ataacactcc
     2401 tctctgccaa cgatcatttc tggagaaaac gcttcacgac tgaggggatg aaaaacattg
     2461 tgtcggatag cctcagacaa ggcatcctta tcgtataaag aacagacttt tgaatgcagt
     2521 gcatttttaa caaaaacgcc tgtttttggt atacataatg ttatcgggca actcagatgt
     2581 tgctcacagc aaggaaaatc tccaggattg acggtaaatg catgagaatt aattctggtc
     2641 tgcactgcat ttctgccccc ttccaaccag aatggggtta aacgaacctg ctccatatat
     2701 aaactgaacg cctgcaggaa agtattgcca tgattaagct gtctctccag actctctgca
     2761 aggcgacgac acctccctcc aagacggtca agaagactgc cctgaatcgg ctccacacta
     2821 aaagcatcca taaatgaaat atggtgcagc ctcagactac gacttcccac aatcagagta
     2881 tcactctgat tgcttcttgc tatattacgc agagcttcca gttcactttc aggcagcgcc
     2941 cttccatctg agatatttaa tacgacgggc atattatctc cctctgtaat gtatttagct
     3001 tatccaggcc aacaacaaat aaacatccac acataaaata aaacagacaa aacattttgg
     3061 caacatacca tcaattattg acttatcatt atttacacca aagcgttgcg atactaaaat
     3121 aattataaac ttgctacatt gtaaatatag acaaataaaa ggaattacta tgccagcaaa
     3181 tatatcagga acacccttca actcatttgg tataagcttt atccagaaac agtcctgctg
     3241 gaggaaatct gatgatatcc tgcgatgttc aatgggtcag aggactatca agttatccac
     3301 taatacgctg aacaaccgaa ttttgacctc cgtcgcccga caaagcacca aagatattaa
     3361 tgcctggaaa agagatgaac agacagttta cccatctcgc gtgatcaacc agggaattga
     3421 taaatattgt gctgaaaata gcagaaacat ttccagtgaa gtacggcaaa gagtttttaa
     3481 attcattgaa aaggattaca gtctcaagtt gaatatcata gcagcgcaaa gctctatcaa
     3541 ccatctcata ataggaaatg gccgtttcgg tgataaaata aatatgcttt gcaagggagt
     3601 gagtagagaa gtaaagaacc agacaatgga tgtaatagcc aatcaactcg cagaccaatt
     3661 cttccaaaag catattagtc cagatgttga catcaaacag ctacgagatg acatccccag
     3721 atatattatg gctgccagcg tcatatcggc ataaatagag atacccttaa cgctaaccag
     3781 aaaaaaaata cctataagag cctgtacata gagttgtgtc gttgcctgat gttgatatgt
     3841 caaatccaac atcaaatagc ggtaaattta tggataaaaa attacaggct ctggttaacg
     3901 aaacaccccc ctcttgctct atccccctct ttcatcattt attacaatat ttatttcaat
     3961 aaaaaccgat attaccaatc acatttatca caatgcaact taatatcggt ttttatcttt
     4021 taatgcctga gcaataggcg gtaatggccg ggatgcctcg gatgcctgtc cacttgtcgg
     4081 tggcggcggt gccgggcggc ttggcttaag gcttgaagta tcaagacttt tcgacttttc
     4141 ataggcagct aaatgatctt ttaatgcctg agcaatgggc ggtaaggacc gggatgatcc
     4201 agatacctgc ccacttgtcg gcggcggtgg agccgggcgg gccggcttaa ggcctgaagc
     4261 ctcaaggctt ttcgattttt cataggcagc caaatgatct tttaatgcct gcgcaatggg
     4321 cggtaaaggg cgggatgccc cggaagcctg tccacttgtc ggcggcggtg gggccggacg
     4381 agagggagta aatgaagtcg ccgggctact cacattaaaa gtcgttctcg cattgatatt
     4441 cgacgtaccg ggagaaaaag gagattgagc cctaatcgga ttcagacgaa cagcctgagg
     4501 ggacactgaa aagccagata accccgcaga gcttacccgg cttgccgcac tagtaatatg
     4561 ccgtcctagt gtagaaacag cttgactaat tccattaagc ataattcatg cctttttata
     4621 tctaatcaac aggaataatt attaatttat attaaaatta aaaatagtta acgactataa
     4681 actattaaat caaacacaca tggaaacata gaaactttcg tacagctata tttttcatta
     4741 aggtattata aatatctctg ttaaaattta tagcatacca aaatgaaatt tatcaattgt
     4801 ttaaactcaa tatgagatta aaacattagt gtccagcttc tattattctc gtggacca
//
LOCUS       DAZUDJ010000167         4652 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.170, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000167 DAZUDJ010000000
VERSION     DAZUDJ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4652
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.170"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1024
                     /locus_tag="ACHY1N_004990"
     CDS             <1..1024
                     /locus_tag="ACHY1N_004990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TyeA family type III secretion system gatekeeper
                     subunit"
                     /protein_id="HFS4047133.1"
                     /translation="ASVFNSNSLDFELESQQLTKKNSSNSYSPLLNLQNELAMITSSS
                     LSETIEGLSLGYRKGSARKEEEGTTTEKLLNDMQELLALTDSDKLKELSLKNSGLLEQ
                     HDPNLAMFGNMPKGEIVALISSLLQSKFVKIELKKKYAKLLLDLLGEDDWELALLSWL
                     GVGELNQEGIQKIKKLYEKAKDEDSEKGASLLDWFMEIKDLPEREKHLKVIIRALSFD
                     LSYMSSFEDKVKTSSIISDLCRVIIFLSLDNYTDIIAISINKDKDVILNEVLSIIEHV
                     WLTEDWLLESPSRVSIVEDKHVYYFHLLKDFFASLPDACFIDREQRDNALLMIGKVID
                     YKEDVI"
     gene            1082..1660
                     /gene="espA"
                     /locus_tag="ACHY1N_004991"
     CDS             1082..1660
                     /gene="espA"
                     /locus_tag="ACHY1N_004991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE translocon
                     filament protein EspA"
                     /protein_id="HFS4047134.1"
                     /translation="MDTSTATSVASANASTSTSTVYDLGSMSKDEVVQLFNEVGVFQA
                     ALLMFAYMYQAQSDLSIAKFADMNEASKESTTAQKMANLVDAKIAEVQSSSNKDAKAK
                     LPQEVIDYIKDPRNGITVSDVKDITVELGAGDLQTVKAAISAKSNNLTTVVNNSQLEI
                     QQMSNTLNLLTSARADIQSLQYRTISAISLGK"
     gene            1673..2815
                     /locus_tag="ACHY1N_004992"
     CDS             1673..2815
                     /locus_tag="ACHY1N_004992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system translocon subunit
                     SctE"
                     /protein_id="HFS4047135.1"
                     /translation="MLNVNSDIQSMRSGASAATATSGINQPEVTSALDLQLVKSTAPS
                     ASWTESTALPTPPAGHSLVTPSAAEDVLSKLFGGISGEVRSRTEGTEPQRSTQNASSG
                     YPYLSQVNNVDPQAMMMMVTLLSLDASAQKVASMKNSNEIYTDGQNKALDNKTLEFKK
                     QLEEQQKAEEKAQKSKIVGQVFGWLGVAVTAIAAIFNPALWAVVAVSATAMALQTAVD
                     VMGDKAPQALKTAAQVFGGVSIAASILTAGIGGVSSLMSKVGDVANKVGSNIVKTVTK
                     LADVFVENVVSKVAATANGFTTSARSIGTTVLNNDSAQYSILAQLSAYAVQNLTRQSE
                     NLGESAKVELDKAAAELRNQASYLQNASQLISDSARVNSRIVSGRV"
     gene            2836..3780
                     /gene="espB"
                     /locus_tag="ACHY1N_004993"
     CDS             2836..3780
                     /gene="espB"
                     /locus_tag="ACHY1N_004993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE translocon
                     pore-forming subunit EspB"
                     /protein_id="HFS4047136.1"
                     /translation="MNTIDYTNQVMTVNSVSENTTGSNAITASAINSSLLTDGKVDVS
                     KLMLEIQKLLGKMVRILQDYQQQQLSQSYQIQLAVFESQNKAIDEKKAAATAALVGGA
                     ISSVLGILGSFAAINSATKGASDIAQQTASTSSKAIDAASDTATKTLTKATESVADAV
                     EDASSVMQQAMTTATRAASRTSDVADDIADSAQRASQLAENAADAAQKASRASRFMAA
                     VDKITGSTPFIAVTSLAEGTKTLPTTVSESVKSNHEISEQRYKSVENFQQGNLDLYKQ
                     EVRRAQDDIASRLRDMTTAARDLTDLQNRMGQSVRLAG"
     gene            3787..4194
                     /gene="cesD2"
                     /locus_tag="ACHY1N_004994"
     CDS             3787..4194
                     /gene="cesD2"
                     /locus_tag="ACHY1N_004994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LcrR family type III secretion system chaperone
                     CesD2"
                     /protein_id="HFS4047137.1"
                     /translation="MVDTFNDEVLNHYLEQKGYTIQKEFLCGSAFFIGWRIETSFFSL
                     AYRLDEQELILCSFEARNQTGLNGPVLSLTRLLEELYHHFSGIKKISAMKSKIGSDSE
                     RQKREELFNYFIRKGAVQQETEDGIWFVMNVNS"
     gene            4231..4452
                     /gene="escF"
                     /locus_tag="ACHY1N_004995"
     CDS             4231..4452
                     /gene="escF"
                     /locus_tag="ACHY1N_004995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE needle filament
                     protein EscF"
                     /protein_id="HFS4047138.1"
                     /translation="MNLSEITQQMGEVGKTLSDSVPELLNSTDLVNDPEKMLELQFAV
                     QQYSAYVNVESGMLKTIKDLVSTISNRSF"
     gene            4458..>4652
                     /locus_tag="ACHY1N_004996"
     CDS             4458..>4652
                     /locus_tag="ACHY1N_004996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscG/YscG/SsaH family type III secretion system
                     needle protein co-chaperone"
                     /protein_id="HFS4047139.1"
                     /translation="MVNDVSANKILVWAAVAAANHKLPKYAESILNVLPQIIPDKKDI
                     AHLEFIILYGLNRKNDAVKAL"
BASE COUNT         1408 a          849 c         1074 g         1321 t
ORIGIN      
        1 cgcatctgtt tttaattcta attcattaga ttttgaattg gaatctcaac aattaacgaa
       61 aaaaaattct tctaatagtt attctccatt attaaattta caaaatgaat tagcgatgat
      121 tactagttca tcgctttctg aaacgattga agggctaagc ctgggatatc gcaaaggcag
      181 tgcaaggaaa gaagaggaag gaacgacaac ggagaagctg cttaatgata tgcaagagct
      241 gcttgctctg accgatagcg ataaattaaa agaactatca ttaaagaaca gtgggctgct
      301 ggaacagcat gatcctaatt tggctatgtt tggtaatatg ccaaaagggg agattgttgc
      361 acttatatct tctttattac aatctaagtt tgttaagatt gaattaaaaa agaaatacgc
      421 caaattatta ttagatttat taggcgaaga tgattgggag ttggctctgc tttcctggtt
      481 aggggtgggt gagttaaatc aggaaggtat ccagaagatc aaaaagcttt atgaaaaggc
      541 caaggatgag gattctgaaa agggagcctc tttacttgac tggtttatgg agattaagga
      601 tcttccagag cgtgagaagc acttaaaggt tattattagg gcgctatcgt tcgatctgtc
      661 ttatatgtct tcttttgaag ataaggtgaa aacatcttca attattagcg atttatgccg
      721 ggtaatcatt tttttatcgc ttgataacta tacagatatt attgcaatct ctattaataa
      781 agataaagat gtcattttaa atgaagtatt gtctattatt gaacatgtat ggttaacaga
      841 agactggctc ctggaaagcc cttctcgggt atcgattgtc gaagataaac atgtttatta
      901 tttccaccta ttgaaagact tttttgcatc attacctgac gcttgtttta ttgataggga
      961 acagagagat aatgcattat taatgattgg taaagtaatt gattataagg aggatgttat
     1021 ttgatattga ttttttaatt gtttttggtc ttgctaagaa agattattaa gaggtatata
     1081 catggataca tcaactgcaa catcagttgc cagtgcgaac gcgagtactt cgacatcgac
     1141 agtctatgac ttaggcagca tgtcgaaaga cgaagtagtt cagctattta atgaagtcgg
     1201 tgtttttcag gctgcgcttc tcatgtttgc ctatatgtat caggcacaaa gcgatctgtc
     1261 gattgcaaag tttgctgata tgaatgaggc atctaaggag tcaaccactg cccaaaaaat
     1321 ggctaatctt gtggatgcta aaattgctga ggttcagagc agttctaaca aggatgcgaa
     1381 agccaaactt cctcaagaag tgatcgacta tataaaagat cctcgtaatg gcattacggt
     1441 cagtgatgta aaagacatta ctgttgaatt aggcgctggt gatttgcaaa cggtgaaggc
     1501 agctatttcg gccaaatcga ataacttgac cacggtagtg aataatagcc agcttgaaat
     1561 acagcaaatg tcaaatacgt taaacttatt aacgagtgca cgtgctgata ttcagtcact
     1621 gcaatacaga actatttcag caatatccct tggtaaataa ccggagataa ctatgctcaa
     1681 tgtaaatagc gatatccagt cgatgaggtc tggggccagc gctgctacgg ctacttcagg
     1741 tattaatcag cctgaagtga cttccgcgct ggatttacaa ctggttaaat ccacggcccc
     1801 atcagcaagt tggacagaaa gtaccgcttt accaacgcca ccggcaggcc actcattagt
     1861 gacgccctct gctgctgagg atgtcctgag taaactgttt ggtggtatta gtggtgaagt
     1921 taggagtcga acagagggaa ccgaaccaca gcgcagcact cagaatgcaa gctctggcta
     1981 tccttatctt tctcaggtga ataacgttga ccctcaggcc atgatgatga tggtcaccct
     2041 gttatccctg gatgcttcag cgcagaaagt tgcgagtatg aaaaactcca acgagatcta
     2101 cacggatggg caaaataagg cgctggataa taaaacgctg gagtttaaaa agcagctcga
     2161 agaacaacag aaagccgaag agaaagcaca aaaaagtaaa attgttggtc aggtctttgg
     2221 ttggttgggc gtcgcggtaa ctgctattgc agctattttt aacccggcac tctgggctgt
     2281 tgttgccgtt agcgcaacag caatggcact gcaaactgca gttgatgtaa tgggcgataa
     2341 ggccccgcag gcgttaaaga cagcagcgca agtctttggc ggagtatcta ttgctgcaag
     2401 tattctgaca gccggcattg gcggggtgtc ttcacttatg tctaaagttg gcgatgtcgc
     2461 taacaaagtt ggttcaaaca tcgtgaaaac agttactaaa ctggccgatg tatttgttga
     2521 gaacgttgtt tcaaaagttg cggcaacggc aaatggattt acgacctctg cacgttctat
     2581 tgggacaact gtgctgaata atgattctgc gcaatacagc atattggctc agttatctgc
     2641 ttacgcggtg caaaacttaa ctcgacagag tgaaaacctg ggtgagagtg cgaaggttga
     2701 gctggataaa gctgcagccg agttgcgaaa ccaggcaagc tatttacaaa atgcttctca
     2761 gttaatatcc gactcagcac gagtaaatag ccgtattgtt agtggtcgag tttaattatt
     2821 aaagagaatt taaatatgaa tactattgat tatactaatc aagtaatgac ggttaattct
     2881 gtttcggaga atactaccgg ctctaatgca attaccgcat ctgctattaa ttcatctttg
     2941 cttaccgatg gtaaggtcga tgtttctaaa ctgatgctgg aaattcaaaa actcctgggc
     3001 aagatggtgc gtatattgca ggattaccaa cagcaacagt tgtcgcagag ctatcagatc
     3061 caactggccg tttttgagag ccagaataaa gccattgatg aaaaaaaggc cgctgcaaca
     3121 gccgctctgg ttggtggggc tatttcatca gtattgggga tcttaggctc ttttgcagca
     3181 attaacagtg ctacgaaagg cgcgagtgat attgctcaac aaaccgcctc tacatcttct
     3241 aaggctattg atgcggcttc tgatactgcg actaaaacgt tgactaaggc aacggaaagc
     3301 gttgctgatg ctgttgaaga tgcatccagc gtgatgcagc aagcgatgac tacagcaacg
     3361 agagcggcca gccgtacatc tgacgttgca gatgacattg ccgattctgc tcagagagct
     3421 tctcagctgg ctgaaaacgc tgcagatgcc gctcagaagg caagtcgggc aagccgcttt
     3481 atggctgcag tagataagat tactggctct acaccattta ttgccgttac cagtcttgcc
     3541 gaaggcacga agacattgcc aacaacggta tctgaatcag tcaaatctaa ccatgagatt
     3601 agcgaacagc gttataagtc tgtggagaac ttccagcagg gtaatttgga tctgtataag
     3661 caagaagttc gcagagcgca ggatgatatc gctagccgtc tgcgtgatat gacaacagcc
     3721 gctcgcgatc tcactgatct tcagaatcgt atgggtcaat cggttcgctt agctgggtaa
     3781 ttgatcatgg tcgatacgtt taatgatgaa gtgcttaatc actatcttga acaaaaaggg
     3841 tacacaatac agaaggagtt tctttgtggc agtgcctttt ttatcggatg gcggattgag
     3901 acctcttttt tctcattagc gtacagactt gatgaacaag aactgatttt gtgctctttt
     3961 gaagcacgta accaaacagg gcttaacggc cctgttttat cactgactcg cttgctcgaa
     4021 gagttgtacc accatttttc gggtattaag aaaatcagtg cgatgaaatc taagattggt
     4081 tcagattcag aacgtcaaaa gcgcgaagag ttgtttaatt acttcatcag aaagggcgct
     4141 gtgcagcaag aaacagaaga cggaatttgg ttcgtaatga atgtaaatag ttagaaattt
     4201 ttatttctat taactattga ggaaaattta atgaatttat ctgaaattac tcaacaaatg
     4261 ggtgaagtag gtaaaacgct gagtgattct gtgccagagt tacttaatag caccgatttg
     4321 gttaatgacc ctgaaaaaat gttagagctg cagttcgcgg ttcagcaata ttctgcttat
     4381 gttaacgtag aaagtggaat gctgaaaacg ataaaagatt tggtctcaac catttccaac
     4441 cgtagctttt aatttttatg gttaatgatg tttctgccaa caagatactg gtgtgggcgg
     4501 ctgtagctgc ggcaaatcat aagcttccca aatatgcaga atctatcctg aatgtattgc
     4561 cgcaaattat acccgataaa aaagatatcg cacatttaga atttattatt ttatatggat
     4621 taaatagaaa aaatgatgcg gtaaaggctc tg
//
LOCUS       DAZUDJ010000168         4514 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.171, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000168 DAZUDJ010000000
VERSION     DAZUDJ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4514
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.171"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..117
                     /locus_tag="ACHY1N_004997"
     CDS             <1..117
                     /locus_tag="ACHY1N_004997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001761574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HFS4047140.1"
                     /translation="EPETQRVIYLREGYEHECFSPLEQFRRKFREIEVGHEH"
     gene            107..1048
                     /locus_tag="ACHY1N_004998"
     CDS             107..1048
                     /locus_tag="ACHY1N_004998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4047141.1"
                     /translation="MSTKLTGYVWDGCAASGMKLSSVAIMARLADFSNDEGVCWPSIE
                     TIARQIGAGMSTVRTAIARLEAEGWLTRKARRQGNRNASNVYQLNVAKLQAAAFSQLS
                     DSDPSKSDASKSDPSKFDASKSGKKAGFHPSESGGDPSVKSKHDPSDKKPSRPDASQP
                     DTQTDEQDFLTRHPDAVVFSPKKRQWGTQDDLTCAQWLWKKIIALYEQAAECDGEVVR
                     PKEPNWTAWANEIRLMCVQDGRNHKQICEMYSRVSRDPFWCRNVLSPSKLREKWDELS
                     LRLSPSISTYTEKREDPYFKSSYDNVDYSQIPAGFRG"
     gene            1045..1539
                     /locus_tag="ACHY1N_004999"
     CDS             1045..1539
                     /locus_tag="ACHY1N_004999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HFS4047142.1"
                     /translation="MSMSLLNEVQKFIEAHPGCTSGDIADAFAGYSRQRVLQSASKLR
                     QSGRVAHYCEGDTRRHFPRLTERAQEPEPQPVRETRPVRNFYVGTNDPRVILCLTRQA
                     EELESRGLYRRAATVWMAAFRESHSQPERNNFLARREQCLQKSSKRAASGEEWYLSGN
                     YVGA"
     gene            1539..2192
                     /locus_tag="ACHY1N_005000"
     CDS             1539..2192
                     /locus_tag="ACHY1N_005000"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001378271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage N-6-adenine-methyltransferase"
                     /protein_id="HFS4047143.1"
                     /translation="MSNKYCQALVELRNKPAHELKEVGDQWRTPDNIFWGINTLFGPF
                     VLDLFTDGDNAKCAAYYTAEDNALAHDWSERLAELKGAAFGNPPYSRASQHEGQYITG
                     MRYIMKHASAMRDKGGRYVFLIKAATSEVWWPEDADHIAFIRGRIGFELPAWFIPKDE
                     KQVPTGAFFAGAIAVFDKTWKGPAISYIGRDELEACGEAFLAQVRQQAEKLVREMVA"
     gene            2189..2515
                     /locus_tag="ACHY1N_005001"
     CDS             2189..2515
                     /locus_tag="ACHY1N_005001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003878599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HFS4047144.1"
                     /translation="MTTLTQCQQQVLDMLISYQKERGFPPTNQEVATMLGYRSVNAAV
                     EHLRALEKKGVITIKRGVARGITLHTAVKDDDSEAVGIIRSLLVGEENARLRAAHWLH
                     ERGLKV"
     gene            2512..2901
                     /locus_tag="ACHY1N_005002"
     CDS             2512..2901
                     /locus_tag="ACHY1N_005002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFS4047145.1"
                     /translation="MKLILPFPPSVNTYWRHPNKGAFAGKSLISAAGRKFQSAACAAI
                     VEQLRRLPKPTSAPASVEIVLFPPDNRIRDLDNYNKALFDALTHAGVWEDDSQVKRML
                     VEWGPVIPEGKVEITISKYEKPAGAAA"
     gene            2921..3718
                     /locus_tag="ACHY1N_005003"
     CDS             2921..3718
                     /locus_tag="ACHY1N_005003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HFS4047146.1"
                     /translation="MNNLMVIDGIEVRRDAYGRYSLNDLHRAAGSLDKHKPAFWLRNE
                     QTERLISELQICNSVNMAPVNVIRGGNNQGTYVCKELVYAYAMWISPSFHLKVIRTFD
                     MVTSTPEKLSGQAADKMQAGVILLDFMRRELNLSNSSVLGACQKLQEAVGLPNLAPRY
                     AIDAPADAPDGSSRPTLSLSALLKQYGIRLTANQAYHQMAKLGIVEQRERYSRTAINN
                     IKKFWSLTAKGCMFGKNITSPANPRETQPHFFESRFPELLKLLDTVH"
     gene            3726..>4514
                     /locus_tag="ACHY1N_005004"
     CDS             3726..>4514
                     /locus_tag="ACHY1N_005004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HFS4047147.1"
                     /translation="MRALLTPEIAPRMGIVLFRPGSELMPLFMQGRVLLEPEPERYSS
                     FASGAVPAATQPLADDPAVRTVFRNEAVIRRAGGVECHESWLLREKGCQWPHSDWHSE
                     NMTTMRHAPGAIRLCWHCDNQLRDQFTERLESMATDNCARWVLSVVRRDLGFDDSHVV
                     TMPELCWWLVRNDLADALPESAARKALRLPKPVVPSVTRESDLVPSVPATSIIQDKAK
                     KVLALKVDPESPESFMLRPKRRRWVNEKYTRWVKTQPCACCGKPA"
BASE COUNT         1092 a         1114 c         1314 g          994 t
ORIGIN      
        1 gagccggaaa cacaacgagt tatctacctc cgcgaaggct atgagcatga gtgcttcagc
       61 ccgctcgaac agtttcgtcg taaattcagg gaaatagagg tcggtcatga gcactaaatt
      121 aaccggctat gtatgggatg gttgcgctgc atcaggcatg aaattatcca gcgtggcaat
      181 tatggcccgc ctggctgatt tcagtaatga cgaaggtgtg tgctggccat caattgaaac
      241 tattgcccgt cagattggcg cggggatgag taccgtcagg acggctatcg cacggctgga
      301 agcagaaggc tggttaacgc gtaaggcgcg tcgccagggt aaccgcaatg cgtcgaatgt
      361 ttatcagctt aacgttgcga agcttcaggc agcggcattt tctcaactgt cagattctga
      421 cccgtcaaaa tctgacgcat caaaatctga cccgtcaaaa tttgatgcgt cgaaatctgg
      481 caaaaaagcg ggttttcacc cgtcagaatc tggcggggat ccgtcagtaa aatcaaaaca
      541 tgatccgtca gataaaaaac cttctcgtcc ggacgcttcg caaccggaca cgcagacgga
      601 tgaacaggat tttttaactc gccatcctga tgcggttgta ttcagcccta aaaagcgcca
      661 gtggggaacg caggatgatt tgacctgcgc acagtggctc tggaaaaaaa tcatcgccct
      721 gtacgagcag gccgccgaat gtgacggcga ggtggttcgt cccaaagaac cgaactggac
      781 agcctgggca aacgaaattc gcctgatgtg tgtgcaggat ggtcgtaatc ataaacaaat
      841 ctgcgagatg tacagccgcg tcagtcgcga tccgttctgg tgccgtaacg tgctcagccc
      901 gtcgaagctg cgggaaaaat gggatgagct ttccctgcgc ttatcgccgt ccatcagcac
      961 atacacagaa aaacgcgaag acccatattt caaatccagt tacgacaacg tggactacag
     1021 ccagatcccg gcaggattca gggggtgagc atgagtcttt tgaatgaagt tcagaaattc
     1081 attgaagccc atccgggctg tacttccgga gacattgcgg atgcttttgc aggttactca
     1141 cggcagcgcg ttctgcagtc agcaagcaag ttacgtcaga gtgggcgtgt ggctcactat
     1201 tgtgaagggg atacacgcag acatttcccg cgcctgactg agagagcgca ggagccggaa
     1261 ccgcaaccag ttcgtgaaac cagacctgtg cgcaatttct atgtcggcac taacgatcca
     1321 cgggtgattt tgtgcctgac ccgccaggct gaagaactgg agtccagggg cctataccgt
     1381 cgtgctgcaa cggtgtggat ggcggcattc cgtgaaagcc actcccagcc agaacgaaac
     1441 aattttctgg cgcgtcgtga gcagtgctta cagaaaagca gcaagcgcgc tgcatcgggt
     1501 gaagagtggt atctgtcagg gaattacgtg ggggcttaat gagtaataaa tattgccagg
     1561 cgctggtgga actgcggaac aaaccagccc atgaactgaa ggaagtgggc gatcagtggc
     1621 gcacgccgga taacattttc tggggaatta acaccctgtt tggcccgttt gttctggatc
     1681 tgttcactga cggtgataac gccaaatgtg ccgcgtatta cacggcggaa gacaacgcgc
     1741 tggcgcatga ctggtcagaa cgtcttgcgg agcttaaagg tgctgccttt ggtaatcccc
     1801 catacagccg cgccagtcag catgaggggc aatacatcac aggcatgcgt tacatcatga
     1861 agcatgccag tgccatgcgt gataaaggtg ggcgctatgt tttcctgatc aaagctgcca
     1921 ccagcgaagt gtggtggccg gaagatgcag atcatattgc ttttattcgc gggcgtatcg
     1981 gttttgaact gcctgcctgg tttatcccga aggatgagaa gcaggtgccg acaggcgctt
     2041 tcttcgctgg tgctattgct gttttcgaca agacctggaa gggaccggca atcagctaca
     2101 tcgggcgcga tgaacttgag gcatgtggtg aggcctttct ggcgcaggtt cgccagcagg
     2161 cagaaaaact ggtcagggag atggtggcat gacgacgtta actcaatgcc agcagcaggt
     2221 gctggatatg ctgatttctt atcagaaaga acgtggcttc ccgccaacca atcaggaggt
     2281 ggcaaccatg ctgggatacc gttcagtgaa tgcagcggta gaacatcttc gcgcactgga
     2341 gaaaaaaggc gtcatcacga taaagcgtgg cgtggcccgg ggcatcacgc ttcataccgc
     2401 ggtgaaggac gacgacagcg aggcggtcgg gattatccgc tcactgcttg tcggtgagga
     2461 aaacgccagg ctgcgtgcag cccactggtt acatgagagg ggcctgaaag tatgaagctg
     2521 atcctgcctt tcccgcccag cgtgaacacg tactggcgac accccaacaa aggggcgttt
     2581 gcaggtaaga gcctgataag cgcggcgggg cgcaaattcc agagcgcggc gtgtgcagca
     2641 atagttgagc agttacgtcg tctgccaaaa ccaacgtcgg cacctgcttc agtggagatc
     2701 gtgttgtttc ctccggataa ccggatccgc gatctggaca actataacaa ggcgctgttt
     2761 gacgccctga cccacgcggg tgtgtgggaa gacgacagtc aggtgaaaag aatgctggtg
     2821 gagtggggac cggttatccc ggaagggaag gtcgagatca ctatcagtaa gtacgagaaa
     2881 ccggcgggtg cagccgcctg attaagagga gaaacgaagt atgaataatc tgatggttat
     2941 tgatggtatt gaagttcgtc gtgatgctta tgggcgttac agcctgaacg atctgcacag
     3001 ggctgccggt tctctggata aacataagcc tgcattctgg ctccgcaatg agcaaaccga
     3061 acgtttaata agcgagttgc aaatttgcaa ctcggtcaat atggcgccag ttaacgttat
     3121 tcgtggcgga aataaccaag ggacgtatgt ctgcaaagaa ctggtgtatg cctatgcaat
     3181 gtggatcagc ccgtcattcc atctgaaggt gatccgtact ttcgatatgg taaccagcac
     3241 accggaaaaa ttatccgggc aggctgctga caagatgcag gctggcgtga tcctgctgga
     3301 ctttatgcgc cgggagttaa atctgtctaa ctcttcagtg cttggtgcct gtcagaaact
     3361 ccaggaggct gttggcttac cgaatctggc accgcgctat gccattgatg ctcctgctga
     3421 cgcgcctgat ggctcaagcc gccccacgct gtcactgagt gcactgctga agcagtatgg
     3481 tatccgcctg acagctaatc aggcatatca ccagatggcg aagctgggga tcgttgaaca
     3541 acgcgaacga tacagccgta ccgcgattaa caacatcaaa aaattctggt cgctgacggc
     3601 gaaaggctgc atgttcggca agaacatcac cagtcctgca aatccgcgcg agacgcagcc
     3661 gcatttcttc gaatcccgat tccctgagct gttaaagcta ctcgataccg ttcattgagg
     3721 tgaccgtgag agcactactg acccctgaaa ttgccccgcg tatggggatc gtattgttca
     3781 ggccaggttc agagctgatg cccctgttta tgcaggggcg tgtcctgctg gagccagagc
     3841 cggaacgtta ttcatctttc gccagtggtg ccgttccggc ggcaacacaa ccgctggcgg
     3901 atgatcctgc cgttcggacc gtgttccgca atgaggcagt gatccgtcgt gctggtggcg
     3961 tggaatgtca tgaaagctgg ttacttcgtg aaaagggctg tcagtggcct cattctgact
     4021 ggcacagcga gaacatgacc acaatgcggc acgctccggg agcaattcgt ctgtgctggc
     4081 actgcgataa ccagctgcgt gaccagttca cggaacggct ggaatcaatg gcaacggata
     4141 actgtgcccg ctgggtgttg tctgtcgtgc gtcgggatct cggttttgat gacagtcacg
     4201 ttgtgacaat gccggaactg tgctggtggc tggttcgtaa tgatctggcg gatgccttac
     4261 cggaaagtgc agcccgtaag gcactgagat taccgaagcc tgttgtgcca tctgtcaccc
     4321 gggaaagtga ccttgtgcct tcggttcctg ccaccagcat catccaggat aaggcgaaaa
     4381 aggtgctggc gctgaaagtg gatccggagt cgccggagtc ttttatgtta cgcccaaaac
     4441 gtcgccgctg ggttaatgaa aagtacacgc gctgggttaa gacgcagccg tgtgcatgtt
     4501 gtggaaagcc tgct
//
LOCUS       DAZUDJ010000169         4439 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.172, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000169 DAZUDJ010000000
VERSION     DAZUDJ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4439
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.172"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            18..2864
                     /gene="eae"
                     /locus_tag="ACHY1N_005005"
     CDS             18..2864
                     /gene="eae"
                     /locus_tag="ACHY1N_005005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_107686095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin type epsilon"
                     /protein_id="HFS4047148.1"
                     /translation="MITHGFYTRTRHKHKLKKTFIMLSAGLGLFFYVNQNSFANGENY
                     FKLSSDSKLLTQNAAQDRLFYTLKTGETVANISKSQGISLSVIWSLNKHLYSSESEMM
                     KAGPGQQIILPLKKLSVEYSALPVLGSAPVVAAGGVAGHTNKMTKMSPDATKSNTTDD
                     KALNYAAQQAASLGSQLQSRSLNGDYAKDTALGMASSQASSQLQAWLQHYGTAEVNLQ
                     SGNNFDGSSLDFLLPFYDSENMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNV
                     FIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRF
                     NGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYR
                     HGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKK
                     QDILSLNIPHDINGTEHSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQ
                     DYQAILPAYVQGGSNIYKVTARAYDRNGNSSNNVQLTITVLPNGQVVDQVGVTDFTAD
                     KTSAKADNVDTITYTATVKKNGVAQANAPVTFSIVSGTATLGANSAKTDGNGKATVTL
                     KSGTPGQVVVSAKTAEMTSPLNASAVIFVDQTKASITEIKADKTTAKANGSDAITYIV
                     KVMKNNQPEANHSVTFSTNFGNLGGNSNTQIVKTDKDGRATVKLTSGVAGNAVVSAKV
                     SEVNTEVKAPEVKFFSVLSIDSNVSIIGTSANGALPNIWLRYGQFKLTAKGGDGKYQW
                     RSQDPSVASVDALTGRVTLLKKGTTTIEVVSGDNQTAMYTINTPTKFISVETQNKVVY
                     SDAEATCRMNNARLPSSTSELKDVYNKWGAANSYEGYKGKKTITAWTQQTEDDKQKGW
                     TSTFDIVTKNEIPSNGSNSKVHVNKANAFAVCVR"
     gene            complement(3138..4358)
                     /gene="escD"
                     /locus_tag="ACHY1N_005006"
     CDS             complement(3138..4358)
                     /gene="escD"
                     /locus_tag="ACHY1N_005006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE inner membrane
                     ring protein EscD"
                     /protein_id="HFS4047149.1"
                     /translation="MLSSYKIKLLNGAMRNRELQLPMGNLTIGTEDNDIVYFPLEQGL
                     NQFLLDIREEGVFLLSPVEFWIDGQPTPYEADQSLPVGKVIDIAGCCFIIGDIDHTLP
                     LSDVPERFSAKNRRKKRLILASVIGAAIALSGAIGSYVLLSPKAEPPAFTRADVYQQL
                     KENKLHAITLVWHGKNVALYGRCESTTDLTPFFNYLKEKNIFYYNNIICNNQIISAIN
                     DILTEYGYKDIIITKGNKPGFFLLSGYIPPSPKWSEVENLLLNTPGVAGWEIHNNSNN
                     KINELASEFKKNKLINYVNIFKKNDVIIVAGEVSQQNESKILAIINAMNKNSNVKILF
                     QNIQPYISADIFPGKILRISGTMKNPTIALDNGTSLGIGSILKGGYVIDAIDPKDGIN
                     ISRPDEYIHIPLSY"
BASE COUNT         1322 a          848 c          974 g         1295 t
ORIGIN      
        1 gtggtggagc ccataacatg attactcatg gtttttatac ccggacccgg cacaagcata
       61 agctaaaaaa aacatttatt atgcttagtg ctggtttagg attgtttttt tatgttaacc
      121 agaattcatt tgcaaatggt gaaaattatt ttaaattgag ttcagattca aaactgttaa
      181 ctcaaaatgc cgctcaggat cgcctttttt atacgttaaa aacaggtgaa actgttgcca
      241 atatttctaa atcacagggg atcagtttat cggtaatttg gtcactgaat aaacatttat
      301 acagctccga aagcgaaatg atgaaggctg ggcctggtca gcagatcatt ttgccactca
      361 aaaaactgtc tgttgaatat agtgccttac ctgtcttagg ttcggcacct gttgttgctg
      421 caggtggtgt cgctggtcat acgaataaaa tgactaaaat gtccccggac gcgactaaaa
      481 gcaacacgac cgatgacaag gctctaaatt atgcggcaca acaggccgcg agccttggta
      541 gccagctcca gtcgcgctca ctgaacggcg attacgcgaa agataccgct cttggtatgg
      601 ccagcagcca ggcttcgtca cagttgcagg cctggttaca acattatgga acggcagagg
      661 ttaatctgca gagtggtaat aactttgacg gtagttcact ggacttctta ttaccgttct
      721 atgattccga aaacatgctg gcatttggtc aggtcggggc gcgttacatt gactcccgct
      781 ttacggcaaa tttaggtgct ggccagcgtt ttttccttcc tgaaaatatg ttgggctata
      841 acgtcttcat tgatcaggat ttttctggtg ataatacccg tttaggtatt ggtggcgaat
      901 actggcgaga ctatttcaaa agtagcgtta acggctattt ccgcatgagc ggctggcatg
      961 agtcatacaa taagaaagac tatgatgagc gcccggcaaa tggttttgat atccgcttta
     1021 atggctattt accatcatat ccggcattag gcgccaaact gatgtacgaa cagtattatg
     1081 gtgataatgt tgctttgttt aattccgata agttgcagtc gaatcctggc gcggcgaccg
     1141 ttggtgtaaa ctacactccg attcctctgg tgacgatggg gatcgattac cgtcatggta
     1201 cgggtaatga aaatgatctc ctttactcaa tgcagttccg ttatcagttt gataaaccgt
     1261 ggtctcagca aatcgagcca cagtatgtta acgagttaag aacattatcg ggcagccgtt
     1321 acgatctggt tcagcgtaat aacaatatta ttctggagta caaaaagcag gatattcttt
     1381 ctctgaatat tccgcatgat attaatggta ctgaacacag tacgcagaag attcaattga
     1441 tcgttaagag caaatatggt ctggatcgta tcgtctggga tgatagtgca ttacgcagtc
     1501 agggcggtca gattcagcat agcggaagcc aaagcgcaca agactaccag gctattttgc
     1561 ctgcttatgt gcaaggtggc agcaatattt ataaagtgac cgctcgcgcc tatgaccgaa
     1621 atggtaatag ttctaataat gtacagctca ctattaccgt tttaccgaat gggcaggttg
     1681 tggaccaggt tggggtaacg gactttacgg ctgataagac atcggctaaa gcggataacg
     1741 ttgataccat tacttatacc gcgacggtta aaaagaatgg tgtagctcag gctaatgccc
     1801 ctgtaacatt tagtattgta tccgggactg caactctcgg ggcaaatagt gccaaaacgg
     1861 atggtaacgg taaggcaacc gtaacgttga agtcgggtac gccagggcag gtcgtcgtgt
     1921 ctgctaaaac cgcggagatg acttcgccac ttaatgccag tgcggttata tttgttgatc
     1981 aaaccaaggc cagcattact gagattaagg ctgataaaac aacagcgaag gcaaatggtt
     2041 ctgatgcgat tacctatatt gttaaagtaa tgaagaataa ccaaccagaa gcaaaccatt
     2101 ctgttacatt ctcaacgaac tttggtaatc tggggggaaa ttctaatacc caaattgtga
     2161 aaacggataa agatggtagg gctacggtaa aactgacatc tggcgttgca ggtaatgctg
     2221 ttgttagtgc aaaagtcagc gaagttaata cagaggttaa ggctcctgag gtaaaattct
     2281 tctcagttct gagcattgat agtaatgtga gtattattgg aacctccgct aatggcgctt
     2341 tacctaatat ttggttgcga tatggtcagt ttaagctgac agccaaaggt ggcgatggga
     2401 aatatcaatg gcgctctcaa gatccaagtg ttgcatcagt tgatgcttta actggtcgag
     2461 ttactttgct gaagaaagga acaacaacaa ttgaagttgt atcgggtgat aaccaaacag
     2521 caatgtatac aattaataca cctacaaaat ttatatctgt ggagacacaa aataaagtag
     2581 tctatagtga tgctgaggca acatgtagaa tgaataatgc acgcttgccg tcatctacga
     2641 gtgagctaaa ggatgtgtat aataaatggg gcgccgccaa tagttatgaa ggctataaag
     2701 gtaaaaaaac aataacagca tggacacagc aaactgagga tgataaacaa aaaggttgga
     2761 ctagtacatt tgacatagtt acaaaaaatg aaatccctag taatggcagt aatagtaaag
     2821 tccacgtgaa taaagctaac gcttttgccg tctgtgtaag atgatcttat aatcattaat
     2881 taatgcccaa ctaagatagt tatcttggtt gggcttaata gatatttatt caaccttaat
     2941 agttgtacct tatttaggta aatttcttta cggcgaggcc attattgaat tgcccaactg
     3001 cgcttgttta atattctgta taaatgcttc tctcagaact gaccatattt ttccaccgct
     3061 ccctattaga aaatttgcta ttacttcacc ctacaataaa taaaaaaccc tccgaagagg
     3121 gggaagacga taataaatta atacgatagc ggaatatgta tatattcgtc tgggcgggag
     3181 atgttgatac catctttagg atcaatcgcg tctatgacat agcctccttt cagaatgcta
     3241 ccaattccca ggcttgtacc gttatcaaga gcaattgttg gattcttcat cgtgccgctg
     3301 attctgagta tttttccggg gaaaatatct gctgaaatgt acggctgaat gttctgaaat
     3361 agtatcttga cgttactatt tttgttcatc gcatttataa tggcaaggat cttactctcg
     3421 ttctgttgag aaacctcccc cgcaacaatg atgacatcat tctttttgaa aatattgaca
     3481 tagtttatta atttattctt tttgaactct gatgccagtt cattgatttt attgttactg
     3541 ttgttatgta tttcccatcc agcaacccct ggcgtattca gtaacagatt ttcaacttcg
     3601 ctccatttgg gtgaaggggg aatgtatccc gataacagga aaaatccagg cttattacct
     3661 tttgtaatga tgatatcctt ataaccgtat tccgttaaaa tatcattaat cgcggagatg
     3721 atttggttat tgcaaatgat attgttgtaa taaaaaatat ttttttcttt caggtaatta
     3781 aaaaatggag ttaaatcagt ggttgattcg caacgtccat aaagcgcgac atttttccca
     3841 tgccatacca gagtgattgc atgaagtttg ttttctttta gctgctggta tacatcagct
     3901 ctggtaaacg ctgggggttc agcttttggg gaaagcaaaa cgtaactgcc tatggcgcca
     3961 gacaacgcaa tcgcagcacc aatcacgcta gccaggataa gacgcttttt acgtcgattt
     4021 ttggcagaga acctttctgg cacatcagac aatggcaagg tgtggtcaat atcaccaatg
     4081 atgaagcaac atcccgctat atcgatgacc tttccgacag gtaatgactg atctgcttca
     4141 taaggggtgg gctgtccatc aatccaaaat tcaaccggag ataaaaggaa aacaccttcc
     4201 tcacgtatat caagtaaaaa ctgattgagg ccttgttcaa ggggaaaata aacaatatcg
     4261 ttatcttctg tgcctatcgt taggtttccc atcggaagtt gtaattcccg attacgcatc
     4321 gcaccattga gaagttttat tttatatgag gataacattt ttaaatttta ttcatcctgg
     4381 tggttgaaca atgagaaaaa atatggtgaa cttacatcaa ctaagaatag agtagaaag
//
LOCUS       DAZUDJ010000170         4390 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.173, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000170 DAZUDJ010000000
VERSION     DAZUDJ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4390
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.173"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..209)
                     /locus_tag="ACHY1N_005007"
     CDS             complement(<1..209)
                     /locus_tag="ACHY1N_005007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFS4047150.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVE"
     gene            complement(324..399)
                     /locus_tag="ACHY1N_005008"
     tRNA            complement(324..399)
                     /locus_tag="ACHY1N_005008"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(364..366),aa:Thr,seq:ggt)
     gene            complement(406..480)
                     /locus_tag="ACHY1N_005009"
     tRNA            complement(406..480)
                     /locus_tag="ACHY1N_005009"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(445..447),aa:Gly,seq:tcc)
     gene            complement(597..681)
                     /locus_tag="ACHY1N_005010"
     tRNA            complement(597..681)
                     /locus_tag="ACHY1N_005010"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(645..647),aa:Tyr,seq:gta)
     gene            complement(690..765)
                     /locus_tag="ACHY1N_005011"
     tRNA            complement(690..765)
                     /locus_tag="ACHY1N_005011"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(730..732),aa:Thr,seq:tgt)
     gene            1127..2077
                     /gene="coaA"
                     /locus_tag="ACHY1N_005012"
     CDS             1127..2077
                     /gene="coaA"
                     /locus_tag="ACHY1N_005012"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFS4047151.1"
                     /translation="MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMT
                     LWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK"
     gene            complement(2106..3071)
                     /gene="birA"
                     /locus_tag="ACHY1N_005013"
     CDS             complement(2106..3071)
                     /gene="birA"
                     /locus_tag="ACHY1N_005013"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HFS4047152.1"
                     /translation="MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLNAEQILGQLDGGSVAVLPVIDSTNQYLLDRIGELK
                     SGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEV
                     LRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESV
                     VNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPV
                     KLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK"
     gene            complement(3068..4096)
                     /gene="murB"
                     /locus_tag="ACHY1N_005014"
     CDS             complement(3068..4096)
                     /gene="murB"
                     /locus_tag="ACHY1N_005014"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFS4047153.1"
                     /translation="MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVL
                     ILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMP
                     GLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRD
                     SIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVSAETAKALLAQFPTAPNYPQAGGSVKLAAGWLIDQCQLKG
                     MQMGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGE
                     VSAVETIS"
BASE COUNT         1123 a         1103 c          984 g         1180 t
ORIGIN      
        1 tattcaacgt gagaagtgtt gatggtgata ccacgagctt tttcttccgg cgcgttatcg
       61 atctggtcga atgcgcgagc agcaccgccg taggttttag ccagtacggt agtgattgca
      121 gcggtcagcg ttgttttacc atggtcaacg tggccgatag taccgacgtt aacgtgcggt
      181 tttgtacgtt caaacttttc tttagacatc gattgtccct ctaagacacg gataaatcgg
      241 tgatatcacc acatcaacca ggcaacatgc ccgacttgtt gaatgcaata aacagaagga
      301 aaaaacaggg aggagaaaag aagtggtgct gataggcaga ttcgaactgc cgacctcacc
      361 cttaccaagg gtgcgctcta ccaactgagc tatatcagca catcttggag cgggcagcgg
      421 gaatcgaacc cgcatcatca gcttggaagg ctgaggtaat agccattata cgatgcccgc
      481 atcctggaac tcggctacct gattttcatt ctgcactgaa tatcgagaga agctctcttt
      541 attcgagccg gtaagcgaac ttatcgtctc gggctacgcc atcgcgtggc cgaaattggt
      601 ggtgggggaa ggattcgaac cttcgaagtc tgtgacggca gatttacagt ctgctccctt
      661 tggccgctcg ggaaccccac cggacttgat ggtgccgact accggaatcg aactggtgac
      721 ctactgatta caagtcagtt gctctaccta ctgagctaag tcggcatcaa gtagcgcgca
      781 ttctatggag acatgcgagt tcatgcaact aaaaaattgc ataatttgtt ttattggtca
      841 cattttatgc gacacgatga agaaacagcc gaacggaggg cagattagca cactttttca
      901 acatcattgt gctcaacaat gcgctcctgc taaaccataa ttctttttat cagatggaat
      961 atctgtcaca ttgcttttca acgatagctt cctggcagag attttttctt attattcctc
     1021 cccatctggt gttaccctcc tgcccattaa cccattcaac agaactgtga cgcgccatgg
     1081 caaatatcgc tttgccgata gagctatgac cgccagaaac atgcttatga gtataaaaga
     1141 gcaaacgtta atgacgcctt acctacagtt tgaccgcaac cagtgggcag ctctgcgtga
     1201 ttccgtacct atgacgttat cggaagatga gatcgcccgt ctcaaaggta ttaatgaaga
     1261 tctctcgtta gaagaagttg ccgagatcta tttacctttg tcacgtttgc tgaacttcta
     1321 tataagctcg aatctgcgcc gtcaggcagt tctggaacag tttcttggta ctaacgggca
     1381 acgcattcct tacattatca gtattgctgg cagtgtcgcg gtggggaaaa gtacaaccgc
     1441 ccgtgtattg caggcgctat taagccgttg gccggaacat cgtcgtgttg aactgatcac
     1501 tacagatggc ttccttcacc ctaatcaggt tctgaaagaa cgtggtctga tgaagaagaa
     1561 aggcttcccg gaatcgtatg atatgcatcg cctggtgaag tttgtttccg atctcaaatc
     1621 cggcgtgcca aacgttacag cccctgttta ctcgcatctt atttatgatg tgatcccgga
     1681 tggagataaa acggttgttc agcctgatat tttaattctt gaagggttaa atgtcttaca
     1741 gagcgggatg gattatccac acgatccaca tcatgtattt gtttctgatt ttgtcgattt
     1801 ttcgatatat gttgatgcac cggaagactt acttcagacg tggtatatca accgttttct
     1861 gaaattccgc gaaggggctt ttaccgaccc ggattcctat tttcataact acgcgaaatt
     1921 aactaaagaa gaagcgatta agactgccat gacattgtgg aaagagatca actggctgaa
     1981 cttaaagcaa aatattctac ctactcgtga gcgcgccagt ttaatcctga cgaaaagtgc
     2041 taatcatgcg gtagaagagg tcagactacg caaataattt gcaggggagc gaatactccc
     2101 ctttcttatt tttctgcact acgcagggat atttcaccgc ccatccaggg ttttattatt
     2161 ccatcctgct caagtaataa agccccctgt ttgtctattc cgcgtgaaat gccaaatatt
     2221 tctttatcac caatgataag tttcactggg cgattaataa aattatccag cttttcccag
     2281 cgcgacagat aaggtgccaa tccttcttgt tcgaagagtt ccaacgcagc acgtaattca
     2341 cgtattagca tggccgccaa cgtattacga tcgagattga tccccgcttc ctgcagcgtg
     2401 atccacccct gattaacgac actctcttca acacggcgca ttgccatgtt gatcccggct
     2461 ccaatgacta tttgcgccgc atcgccagtt ttgccagtca gctccacaag aatgcctgcc
     2521 agcttgcgat cctgcagata gaggtcatta ggccatttga cacgaacttt atctgctccc
     2581 agcttgcgta atacttccgc catcacgata ccgataacca gacttaaacc aatcgccgcc
     2641 gccgggcctt gttccagacg ccagaacatc gacaaatata agtttgcgcc aaaaggcgaa
     2701 aaccatttcc gcccccggcg accacggcca gcctgctggt attctgcaac acaggcatcg
     2761 cccgatttaa gctctccgat acgatcaaga aggtactgat tcgtggagtc aataactggc
     2821 agcacggcta cactaccgcc atccagctga cccaatatct gttcagcatt aagtaactgg
     2881 atgggctcag gcaggctgta tcctttaccc ggaacggtaa agacatcaac gccccagtca
     2941 cgcagtgtct gaatgtgttt attaatagcc gcccggctca ttcccagcgt ttcacccaac
     3001 tgctcgccag agtgaaattc accgttcgct aacagggcaa tcaatttcag tggcacggtg
     3061 ttatccttca tgaaattgtc tccactgcgc tcacttcacc tgatgcacca ataaagcgga
     3121 cttcaggctc aagccagaca ttaaattttt cacccacttt ttgtcttaca tggtgtgcca
     3181 gttgcaccac atcttcgctt tttgcattgt cttcattaat gagaactaac gcctgttgac
     3241 ggtgcaccgc agccccaccc atttgcatcc cttttagctg gcactgatca ataagccaac
     3301 ctgctgccag ttttactgaa ccacccgcct gggggtaatt tggtgctgtt ggaaattgcg
     3361 ccagtaatgc tttagccgtt tcggcagata caacagggtt tttgaagaaa ctaccggcat
     3421 tgccattcac ttttggatca gggagtttgg tggtgcgcat atgacacacc gcattaaata
     3481 cttgctgtgg cgttactgtt gtaggatcca gacgagttaa gtcaccatac gttagtacag
     3541 gttgccactc ttttggcaga cgcagaccta cggctacaat ggcgaagcga tcctggtatt
     3601 catgtttaaa aatactgtcg cgatagccaa aacggcactc tttggcagtt aagcgcactt
     3661 gcttgcctgt cgccagttca acacaatcaa cataagcgca aactcgctgt aattctacgc
     3721 cataagcacc aatattctgg ataggtgatg agccgacaca accaggaatt aatgccagat
     3781 tttccagacc aggcatacct tcctgcaaag tgtattttac caggcgatgc cagttttctc
     3841 cggctcctac atgtaaatac cacgcatcag gttcatcatg aatttcgata cctttgatcc
     3901 ggttgatgat caccgtgccg cgatagtctt ccagaaaaag tacattactt ccttcaccca
     3961 gaataagaac gggttgtcct tctgcggttg catactgcca ggcattgagt aattgttgtt
     4021 cgtcttcggc acatacaatg tgctgagcat tatgatcaat gccaaatgtg ttccagggtt
     4081 ttaaggagtg gttcatagct gctttcctga tgcaaaaacg aggctagttt accgtatctg
     4141 tggggggatg gcttgtagat atgacgacag gaagagtttg tagaaacgca aaaaggccat
     4201 ccgtcaggat ggccttctgc ttaatttgat gcctggcagt ttatggcggg cgtcctgccc
     4261 gccaccctcc gggccgttgc ttcgcaacgt tcaaatccgc tcccggcgga tttgtcctac
     4321 tcaggagagc gttcaccgac aaacaacaga taaaacgaaa ggcccagtct ttcgactgag
     4381 cctttcgttt
//
LOCUS       DAZUDJ010000171         4388 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.174, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000171 DAZUDJ010000000
VERSION     DAZUDJ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4388
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.174"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(52..750)
                     /locus_tag="ACHY1N_005015"
     CDS             complement(52..750)
                     /locus_tag="ACHY1N_005015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030430 - host cell cytoplasm [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HFS4047154.1"
                     /translation="MQDIHEESLNESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNE
                     KGEAVTWQGRQYQAYPIDGSGFEMNGKGSSARPSLTVSNLFGLVTGMAEDLQSLVGAT
                     VVRRRVYARFLDAVNFVAGNPEADPEQELSDRWVVEQMSELTAMTASFVLATPTETDG
                     ALFPGRIMLANTCMWDYRGDECGYNGPAVADEFDNPTTDIRKDRCSKCMRGCEMRGMV
                     ANFGGFLSINKLSQ"
     gene            complement(750..1079)
                     /locus_tag="ACHY1N_005016"
     CDS             complement(750..1079)
                     /locus_tag="ACHY1N_005016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047155.1"
                     /translation="MKTFRWKVKPDMEVNSQPSVREVRFGDGYSQRMAAGLNADLKTY
                     RVTLSVTREEARHLEAFLAEHGGWKAFLWTPPYAWRQIKVTCAAWSSRVRMLRVEFSA
                     EFKQVVN"
     gene            complement(1076..3655)
                     /locus_tag="ACHY1N_005017"
     CDS             complement(1076..3655)
                     /locus_tag="ACHY1N_005017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4047156.1"
                     /translation="MSQPVGDLVIDLSLDAVRFDEQMSRVRRHFSGLETDARKTVGVV
                     EQNLSRQALAAQKAGISVGQYKAAMRTLPAQFTDIATQLAGGQNPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGTITLPMVGVTSLAVATGALAYAWYQGDSTLSAFNKTLVLSGNQS
                     GLTADRMLTLSRAGQAAGLTFNQASESLAALVNVGVRGGAQFDAINQSVARFASASGV
                     EVDKVAEAFGKLTTDPTSGLMAMARQFRNVTAEQIAYVAQLQRSGDEAGALQAANDAA
                     TKGFDEQTRRLKENMGTLETWADKTGKAFKSMWDAILDIGRPESSADMLASAQKAFDE
                     ADKKWQWYQSRSQRRGKTSSFRANLQGAWDDRENARLGLAAATLQSDMEKAGELATRD
                     RAERDASQLKYTGEAQKAYERLLTPLEKYTNRQEELNKALKDGKILQADYNTLMAAAK
                     KDYESTLKKPKSSGVKVSAGERQEDLTHAALLALETELRTLEKHSGANEKISQQRRDL
                     WKAESQFAVLEEAAQRRQLSAQEKSLLAHEQETLEYKRQLADLGDKVEYQKRLNELAN
                     QAVRFEQQQSAKQAAISAKARGLTDRQAQRESESQRLRDVYGDNPDALAKATSALKNT
                     WSAEEQLRGSWMAGLKSGWGEWAESATDSFSQVKSVATQTFDGIAQNMAAMLTGSEQS
                     WRGFTRSVLSMLTEIFLKQAMVGIVGSIGSAMGGAFGGGASASTGTAIQAAAANFHFA
                     TGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYAEGGYVGGAGSPAQ
                     MRRAEGISFNQNNHVVIQNDGTNGQAGPQLMKAVYDMARKGAQDEIQAQMRDGGVFSG
                     GRR"
     gene            complement(3636..4049)
                     /locus_tag="ACHY1N_005018"
     CDS             complement(3636..4049)
                     /locus_tag="ACHY1N_005018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HFS4047157.1"
                     /translation="MGRPDWRAMLAGMTSTEYADWRHFYRTHYFHDTQLDMHFSGLTY
                     AVLSLFFCDPDMHPSDFSLLAPRREKAQTEMPDEEKMLMQKAAGLAGGVRFGGDGGRE
                     ILSSADVADVSEDDVALMMASAGIPGGVRYVPAGW"
     gene            complement(4076..>4388)
                     /locus_tag="ACHY1N_005019"
     CDS             complement(4076..>4388)
                     /locus_tag="ACHY1N_005019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HFS4047158.1"
                     /translation="SSGNLQVSVEDLVRTGAFLVAMSLWHNHPQKTASPSMNEAVMQI
                     EQEVLTTWPADAIARAEDVVLRLSGMSGAVHADTDSTEVAKYNALTDDDFSAGKSSTA
                     S"
BASE COUNT          872 a         1509 c         1055 g          952 t
ORIGIN      
        1 cacaccgccg ggcatgcgcc agaatcgctg attctgtctg tgtcattgga tttactgcga
       61 aagtttgtta atggaaagga aaccgccaaa attagccacc atgccgcgca tctcacaccc
      121 gcgcatgcac ttgctgcatc tgtccttacg gatatccgtg gtggggttgt cgaactcatc
      181 cgccaccgca ggaccgttat acccgcattc atctccccgg taatcccaca tacaggtgtt
      241 cgccagcatg atgcgaccgg gaaacagcgc tccgtccgtc tccgtcggtg ttgccagcac
      301 aaacgaggct gtcatggccg tcagctctga catctgctcc accacccagc ggtcgctcag
      361 ctcctgctcc gggtccgctt ccggattgcc cgccacaaaa ttcaccgcat ccagaaaacg
      421 ggcatacacc cggcggcgga ccaccgtggc ccccaccagg ctctgcaggt cctccgccat
      481 tccggtgacc agaccgaaca gattggacac cgtcagcgac gggcgggcac tgctgccctt
      541 cccgttcatc tcaaagccac tgccgtcaat cgggtatgcc tgatattgcc gcccctgcca
      601 ggtaaccgcc tccccttttt cattcagctc attgcagaaa aaataccgct caccaccctg
      661 taccgtcagg tcgatttccc agagtaccac ccgcggtgac tgctctgatt taaccgactc
      721 gttcagactt tcttcgtgaa tatcctgcat cagttcacca cctgcttaaa ctccgcgctg
      781 aattcaaccc gcagcatgcg aacccgtgat gaccaggcgg cacaggtcac ctttatctgc
      841 cgccaggcat aaggcggtgt ccacagaaac gccttccagc caccgtgctc tgccaggaat
      901 gcctccagat gtcgggcctc ctcccgggtc acggaaagcg tcacacggta tgttttcagg
      961 tcagcattca gccccgccgc catacgctgc gaatacccgt caccaaaacg cacttcacgc
     1021 accgatggct gcgagttcac ctccatatcc ggcttcactt tccagcgaaa tgttttcatc
     1081 gcctgcctcc ggaaaagacg ccgccatcac gcatctgcgc ctgaatctca tcctgcgccc
     1141 ccttgcgggc catgtcatac accgccttca tcagctgcgg ccccgcctgt ccgttggtgc
     1201 cgtcgttctg aatcaccacg tgattgttct gattaaaact aatgccttcc gcccgccgca
     1261 tctgcgccgg acttccggca ccgcccacat aaccaccttc cgcatacccg cgcatcagac
     1321 gatacaggtt gccgacgcca atccggctgg ttgcctcctt cgtgaagaca aactccccgc
     1381 ggtggacaat accggcaggt tcgtatttgc caccggttcc cgtaaatcct ccggtcgcga
     1441 aatggaagtt cgccgccgca gcctgaatgg ccgtccccgt ggaggcagac gccccaccac
     1501 cgaaagcacc acccatggcg ctgccaatac tcccgacaat ccccaccatg gcctgcttca
     1561 gaaaaatctc tgtcagcatg gagagcacag aacgggtgaa accacgccag ctctgttcgc
     1621 tgccggtcag catcgctgcc atattctgtg caataccgtc aaaggtctgc gtggccacgc
     1681 ttttaacctg cgaaaaactg tccgtcgcac tttctgccca ctcgccccag ccggacttca
     1741 gaccggccat ccagcttcca cgaagctgct cctccgcaga ccaggtgttc ttcagtgcag
     1801 atgtggcctt cgccagcgca tccggattat caccgtacac gtcacgaagg cgctgcgatt
     1861 ccgactcccg ctgtgcctga cggtccgtca gcccccgggc ttttgcgctg attgcagcct
     1921 gcttcgcact ctgctgctgt tcaaaccgca cagcctgatt tgccagctca ttcagccgtt
     1981 tctggtattc aaccttgtca cccaggtcag ccagctggcg tttgtactcc agcgtctctt
     2041 gctcatgggc cagcagggat ttctcctgtg cagacagctg gcgacgttgc gccgcctcct
     2101 ccagtaccgc gaactgactc tccgccttcc acaaatcccg gcgctgctgg ctgattttct
     2161 cattcgctcc gctgtgcttc tccagcgtcc ggagctcggt ttcaagcgcc agcagcgccg
     2221 catgcgtcag gtcttcctga cgctcaccgg ctgacacttt aacacctgac gacttcggct
     2281 ttttcagcgt cgattcataa tcctttttcg ccgccgccat cagcgtgttg taatccgcct
     2341 gcaggatttt cccgtctttc agggccttat tcagctcttc ctgccggtta gtatatttct
     2401 ccagcggcgt cagcagacgc tcatacgcct tctgcgcctc tccggtatac ttcagctgtg
     2461 atgcgtcccg ttcggcccgg tccctggtag ccagttcacc ggctttttcc atatccgact
     2521 gcagcgtggc cgctgccagc cccagacggg cattttcccg gtcatcccat gcgccctgca
     2581 ggttggcacg gaaagaggag gtctttcccc ggcgctggct ccggctctgg taccactgcc
     2641 attttttatc cgcctcatcg aatgccttct gcgcactggc aagcatatcc gctgaggatt
     2701 ccggacgacc aatatccaga atggcatccc acatcgattt gaacgccttc cctgttttat
     2761 ccgcccaggt ctccagcgtc cccatgtttt ctttcaggcg acgggtctgc tcatcaaagc
     2821 ctttcgtggc agcatcgttc gccgcctgta aggccccggc ctcatcaccg gaacgctgca
     2881 gctgcgcaac atacgcaatc tgctctgccg tcacgttacg gaactggcgc gccatcgcca
     2941 tcagccccga cgtcgggtcg gtggtcagtt ttccgaaagc ctctgcaacc ttgtccacct
     3001 ccacaccgga tgcagaagca aaacgcgcga cactctggtt gatggcatca aactgtgcac
     3061 caccacgcac accgacattc accagggctg ccagtgactc actcgcctgg ttaaacgtca
     3121 gccctgcggc ctgtccggct ctggagagcg tcagcatgcg atcggcagtc agtccggact
     3181 gattaccgga aagaaccagg gttttattaa acgctgaaag cgtggaatcc ccctggtacc
     3241 aggcgtacgc cagcgcacct gtcgccaccg ccagcgaggt gaccccgacc atcggcaggg
     3301 tgatcgtacc ggcaagtccc ctgaacatgg ggatcatccc gccgaaggag tccttcacct
     3361 gaccgccctg ttgcagcagg atcagccagg gattctgacc accggcaagc tgcgtggcga
     3421 tatccgtaaa ctgtgcgggc agggttcgca tggccgcttt atactgcccg acggaaatcc
     3481 cggctttttg tgcagccagc gcctgacgac tcaggttctg ctcaacgaca ccgacggttt
     3541 ttctggcgtc agtctccagt ccggaaaaat gacgccttac ccggctcatc tgctcatcga
     3601 aacggaccgc atccagactc aggtcaataa caagatcacc aaccggctgg gacatatctc
     3661 acacctcccg gaatccccgc tgaagccatc attaatgcga catcatcctc gctgacatcc
     3721 gccacatccg cagacgataa aatctcacgc cctccgtccc caccaaaccg tacgcctccg
     3781 gcaagtcctg ccgctttctg catcagcatt ttttcctcat ccggcatctc cgtctgcgct
     3841 ttctcacgcc ggggggcaag cagactgaaa tcagagggat gcatatccgg atcgcaaaaa
     3901 aacaggctga gtacggcgta cgtcagcccg gaaaaatgca tatccagttg ggtatcgtga
     3961 aaataatgcg tacggtaaaa atgtcgccag tcggcatatt cggtggatgt catcccggca
     4021 agcatggcgc gccagtcagg cctccccatc tcacgcgcca gtctgagggc aaaattcagc
     4081 tcgccgtcga agactttccc gcagaaaaat catcatcagt cagcgcgtta tatttcgcca
     4141 cttcggtgct gtcagtatcc gcatgaacag ccccgctcat cccggacaga cgcaacacca
     4201 catcttccgc ccgggcaatg gcatccgcag gccaggtggt gagcacctcc tgttcgatct
     4261 gcatcacagc ctcattcatt gacggtgatg ccgttttctg cggatggtta tgccacaggg
     4321 acatcgccac cagaaacgcg ccggttctga cgagatcttc cacgcttacc tgcaggttgc
     4381 cgctggat
//
LOCUS       DAZUDJ010000172         4365 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.175, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000172 DAZUDJ010000000
VERSION     DAZUDJ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4365
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.175"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..108)
                     /locus_tag="ACHY1N_005020"
     CDS             complement(<1..108)
                     /locus_tag="ACHY1N_005020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFS4047159.1"
                     /translation="MTNTAKILNFGRGNFAGQERNVADLDDGYARLSNML"
     gene            complement(141..434)
                     /locus_tag="ACHY1N_005021"
     CDS             complement(141..434)
                     /locus_tag="ACHY1N_005021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda phage CII family protein"
                     /protein_id="HFS4047160.1"
                     /translation="MVRANKRNEALRIESALLNKIAMLGTEKTAEAVGVDKSQISRWK
                     RDWIPKFSMLLAVLEWGVVDDDMARLARQVASILTNKKRPAATERSEQIQMEF"
     gene            complement(554..769)
                     /locus_tag="ACHY1N_005022"
     CDS             complement(554..769)
                     /locus_tag="ACHY1N_005022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4047161.1"
                     /translation="MQTLSERLKKRRIALKMTQTELATKAGVKQQSIQLIEAGVTKRP
                     RFLFEIAMALNCDPVWLQYGTKRGKAA"
     gene            873..1505
                     /locus_tag="ACHY1N_005023"
     CDS             873..1505
                     /locus_tag="ACHY1N_005023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family protein"
                     /protein_id="HFS4047162.1"
                     /translation="MSISSRVKSKRIQLGLNQAELAQKVGTTQQSIEQLENGKTKRPR
                     FLPELASALGVSVDWLLNGTSDSNVRFVGHVEPKGKYPLISMVRAGSWCEACEPYDIK
                     DIDEWYDSDVNLLGNGFWLKVEGDSMTSPVGQSIPEGHMVLVDTGREPVNGSLVVAKL
                     TDANEATFKKLVIDGGQKYLKGLNPSWPMTPINGNCKIIGVVVEARVKFV"
     gene            1595..1906
                     /locus_tag="ACHY1N_005024"
     CDS             1595..1906
                     /locus_tag="ACHY1N_005024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001434479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047163.1"
                     /translation="MNGDRYEFTKDSTEDSVFNVTINGDKSSVYESVSGVYPEMKYTA
                     LSSNTMVGEYQSGGGITVETWSITTDKKALYSKVMNIPGMQQLTSTKSFVGDVVGTCN
                     Q"
     gene            2126..2581
                     /locus_tag="ACHY1N_005025"
     CDS             2126..2581
                     /locus_tag="ACHY1N_005025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein N"
                     /protein_id="HFS4047164.1"
                     /translation="MCDTKRSIGRKCESGLAANVPLRGVFVQDYDSHTQPKLTDRRIQ
                     MDAQTRRRERRAEKQAQWKAANPLLVGVSAKPVNRPILSLNRKPKSRVESALNPIDLT
                     VLAEYHEQIESNLQRIERKNHRVWYSKPGEFGITCQGRQKVKGESIPLA"
     gene            2590..3459
                     /locus_tag="ACHY1N_005026"
     CDS             2590..3459
                     /locus_tag="ACHY1N_005026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001383906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047165.1"
                     /translation="MKKIDYKSIPKPIDSASERKKHKKEAEKLANYISFIRNNAHGDG
                     DKKLLSDARTQAFGILRKQMQYRLHPGYIIEIRPTERQLFLLNSVFDFVNVVGDLIDR
                     SVDKDPDTNSFLLTNKEYLYGKFGINGWQKYVRFLRAFVDAYKNSDMIYTYLPGGDNC
                     TLSADNRIFIPVLGLGLINAVNEKDVIIVKQWRKYEGYRYLPCFDILKIQNKFYVKIK
                     YKEDIFFLRKNIDLLQELSGTIDVILGSRFIKELKESRSFSRVEISESELWGISNNPV
                     NHAHQRNPNKKWS"
     gene            3648..4016
                     /locus_tag="ACHY1N_005027"
     CDS             3648..4016
                     /locus_tag="ACHY1N_005027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2528 family protein"
                     /protein_id="HFS4047166.1"
                     /translation="MSNIKKYIIDYDWKASIEIEIDHDVMTEEKLHQINNFWSDSEYR
                     LNKHGSVLNAVLIMLAQHALLIAISSDLNAYGVVCEFDWNDGNGQEGWPPMDGSEGIR
                     ITDIDTSGIFDSDDMTIKAA"
     gene            4089..4253
                     /locus_tag="ACHY1N_005028"
     CDS             4089..4253
                     /locus_tag="ACHY1N_005028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease FtsH-inhibitory lysogeny factor CIII"
                     /protein_id="HFS4047167.1"
                     /translation="MQYAIAGWPVAGCPSESLLERITRKLRDGWKRLIDILNQPGVPK
                     NGSNNYGYPD"
     gene            4222..4365
                     /gene="kil"
                     /locus_tag="ACHY1N_005029"
     CDS             4222..4365
                     /gene="kil"
                     /locus_tag="ACHY1N_005029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309204.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitory peptide Kil"
                     /protein_id="HFS4047168.1"
                     /translation="MDQTIMAIQTKFTIATFIGDEKMFREAVDAYKKWILILKLRSSK
                     SIH"
BASE COUNT         1341 a          892 c          943 g         1189 t
ORIGIN      
        1 cagcatattt gatagtctgg cgtaaccatc atcgagatct gccacattac gctcctgtcc
       61 ggcaaagtta cctctgccga agttgagtat ttttgctgta tttgtcataa tgactcctgt
      121 tgatagttcc agtaataacc tcagaattcc atctggattt gttcagaacg ctcggttgcc
      181 gccgggcgtt ttttattggt gagaatcgaa gcaacttgtc gtgccaatcg agccatgtcg
      241 tcgtcgacga caccccattc aagaacagca agcagcattg agaactttgg aatccaatcc
      301 ctcttccacc tgctgatctg cgacttatca actcccacag cttccgctgt cttctcagtt
      361 ccaagcattg cgattttgtt aagcaacgca ctctcgattc gtagagcctc gttgcgtttg
      421 tttgcacgaa ccatatgtaa gtatttcctt agataacaat tgattgaatg tatgcaaata
      481 aatgcataca ccataggtgt ggtttatttt gatgcccttt ttcagggctg ggatgtgtaa
      541 gagcgggaat gtcttaagcg gctttaccgc gtttagttcc gtactgtaac caaaccggat
      601 cacagttaag cgccatagca atctcaaaca agaagcgcgg tcgcttggtt actccagctt
      661 caatcagttg aattgattgc tgtttaacac cggctttggt tgccagttcg gtttgcgtca
      721 tttttaacgc aattcgcctc ttcttgaggc gttcagaaag agtttgcata tcgcctccat
      781 caacaaactt tcttgtattt tcatacaatg tatcttgttt gtcaaataca gtttttcttg
      841 tgaagattgg gggtaaataa cagaggtggc ttatgagtat ttcttccagg gtaaaaagca
      901 aaagaattca gcttggactt aaccaggctg aacttgctca aaaggtgggg actacccagc
      961 agtctataga gcagctcgaa aacggtaaaa ctaagcgacc acgcttttta ccagaacttg
     1021 cgtcagctct tggcgtaagt gttgactggc tgctcaatgg cacctctgat tcgaatgtta
     1081 gatttgttgg gcacgttgag cccaaaggga aatatccatt gattagcatg gttagagctg
     1141 gttcgtggtg tgaagcttgt gaaccctacg atatcaagga cattgatgaa tggtatgaca
     1201 gtgacgttaa cttattaggc aatggattct ggctgaaggt tgaaggtgat tccatgacct
     1261 cacctgtagg tcaaagcatc cctgaaggtc atatggtgtt agtagatact ggacgcgagc
     1321 cagtgaatgg aagccttgtt gtagccaaac tgactgacgc gaacgaagca acattcaaga
     1381 aactggtcat agatggcggt cagaagtacc tgaaaggcct gaatccttca tggcctatga
     1441 ctcctatcaa cgggaactgc aagattatcg gtgttgtcgt ggaagcgagg gtaaaattcg
     1501 tatgatcagg attgcggcgc tactctcaat actcttaact accagcgcca attctgaatg
     1561 ctggattgtc acaaacctgc acgggtacgg ggcaatgaat ggcgatcgtt acgagtttac
     1621 aaaagacagc acggaagatt ccgttttcaa cgtaacaata aatggcgata aatcatcagt
     1681 ttatgaatca gtttctggcg tctatccaga gatgaaatac actgctttgt catcgaacac
     1741 tatggtagga gaataccagt ctggaggagg cataaccgtt gaaacttggt caatcactac
     1801 agacaaaaaa gctctttact ccaaagtaat gaacatccca ggtatgcaac aacttacatc
     1861 aaccaaatcc tttgttggtg atgtagtcgg aacctgcaat cagtaatccc cacctcaatc
     1921 tcgataacaa aaaaacaaac tattttccgt ttaaaaacaa tggagtttgt ttttcacgcc
     1981 cttttttaca atatttcttg tttacaacat acaatcttcc ttgtaatttt aagccatcag
     2041 caggacgcac tgaccaccat tgaaggtgag gctcttaaaa attaagccct gaagaagggc
     2101 agcattcaaa gcagaaggct ttggtgtgtg tgatacgaaa cgaagcattg gccggaagtg
     2161 cgaatccgga ttagctgcca atgtgccatt gcggggtgtt ttcgttcagg actacgactc
     2221 ccacacacaa ccaaagctaa ctgacaggag aatccagatg gatgcacaaa cacgccgccg
     2281 cgaacgtcgc gcagagaaac aggctcaatg gaaagcagca aatcccctgt tggttggggt
     2341 aagcgctaaa ccagttaacc gccctattct ctcgctgaat cgcaaaccga aatcacgagt
     2401 agaaagcgca ctgaatccga tagaccttac ggtgctggct gaataccacg aacagattga
     2461 aagcaacctg caacgtattg agcgcaagaa tcatcgagtt tggtatagca agccaggtga
     2521 gttcggtata acttgtcaag gaagacaaaa ggttaaaggg gaatccattc cattggcatg
     2581 aggtacgtaa tgaagaagat tgattacaag tccataccaa aaccaataga ctcagcatca
     2641 gagcgaaaaa aacacaaaaa agaggctgaa aaattagcaa attatatcag ttttattaga
     2701 aacaatgctc acggcgatgg cgacaagaag ttgctttcag atgctcggac ccaagcgttc
     2761 ggtatacttc gtaagcagat gcaatatcgt cttcatcctg gctacataat tgaaattcgc
     2821 cctactgaaa gacaattgtt cttattaaac tctgtctttg actttgtaaa cgtagttgga
     2881 gatcttatcg acaggtctgt agataaggat cctgatacaa atagttttct tctaacaaat
     2941 aaagaatact tatatggtaa attcggtata aacggatggc aaaaatatgt acgcttctta
     3001 cgtgcattcg ttgatgcgta taaaaattcc gacatgattt atacatattt gcctggtggt
     3061 gataattgta cgctttcggc agacaataga atattcatac ctgtacttgg tcttgggctg
     3121 attaatgcag taaatgaaaa agatgttata attgttaagc agtggcgaaa atatgaggga
     3181 tatagatatc tgccatgctt tgatatatta aaaatacaga ataaattcta tgtaaaaatt
     3241 aaatataaag aagatatttt cttcctcaga aaaaacatag atcttttaca agaactttct
     3301 ggtacaatag atgtcatctt aggttctagg tttataaaag aactgaaaga aagcaggtct
     3361 ttctctcgtg tagagataag cgagtcagag ttatggggta tatcaaataa tcctgtaaac
     3421 cacgctcacc aacgaaaccc aaacaaaaag tggtcataac ccgctcaggc ggatttcatt
     3481 ttcacgcaaa caacagaata aacacagcgc tgtgtattca ttccaacgag tgaatacacg
     3541 gagcaatgtc gctcgtaact aaacaggagc cgacttgttc tgattattgg aaatcttctt
     3601 tgccctccaa gatgagggcg attttttatc tgtgaggata tgaacagatg tcaaacatca
     3661 aaaaatacat cattgattac gactggaaag catcaataga aattgaaatc gaccatgacg
     3721 taatgacaga ggaaaaactt caccagatta ataatttctg gtcagactct gaataccgac
     3781 tcaataaaca cggctctgta ttaaatgctg tattaatcat gctggcgcaa catgctctgc
     3841 ttatagcaat ttcaagcgac ttaaatgcat atggtgttgt gtgtgagttc gactggaatg
     3901 atggaaatgg tcaggaagga tggcctccaa tggatggtag tgaaggaata agaattaccg
     3961 atatcgatac atcaggaata tttgattcag atgatatgac tatcaaggcc gcctgagcgc
     4021 ggcgttaccg cataccaatt acgcttcact cgaggcgttt ttcgttatgt ataaataagg
     4081 agcacaccat gcaatatgcc attgcagggt ggcctgttgc tggctgccct tccgaatctt
     4141 tacttgaacg aatcacccgt aaattacgtg acggatggaa acgccttatc gacatactta
     4201 atcagccagg agtcccaaaa aatggatcaa acaattatgg ctatccagac taaattcact
     4261 atcgccactt ttattggcga tgaaaagatg tttcgtgagg ccgtcgacgc ttataaaaaa
     4321 tggatattaa tactgaaact gagatcaagc aaaagcattc actaa
//
LOCUS       DAZUDJ010000173         4354 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.176, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000173 DAZUDJ010000000
VERSION     DAZUDJ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4354
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.176"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(14..280)
                     /gene="ariR"
                     /locus_tag="ACHY1N_005030"
                     /gene_synonym="ymgB"
     CDS             complement(14..280)
                     /gene="ariR"
                     /locus_tag="ACHY1N_005030"
                     /gene_synonym="ymgB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm/acid-resistance regulator AriR"
                     /protein_id="HFS4047169.1"
                     /translation="MLEDTTIHNAITDKALASYFRSSGNLLEEESAVLGQAVTNLMLS
                     GDNVNNKNIILSLIHSLETTSDILKADVIRKTLEIVLRYTADDM"
     gene            complement(309..581)
                     /locus_tag="ACHY1N_005031"
     CDS             complement(309..581)
                     /locus_tag="ACHY1N_005031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YmgA"
                     /protein_id="HFS4047170.1"
                     /translation="MKTSDNERIKYEITGQAVIQILRMKINFSLQTLIKQLLVMKSAE
                     EDAFRRDLIDSIIRDFSNSDSGGPNRRTATADNKSMFNGKKINRIH"
     gene            complement(624..860)
                     /gene="ycgZ"
                     /locus_tag="ACHY1N_005032"
     CDS             complement(624..860)
                     /gene="ycgZ"
                     /locus_tag="ACHY1N_005032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein YcgZ"
                     /protein_id="HFS4047171.1"
                     /translation="MHQNSVTLDSAGAITRYFAKANLPTQQETLGEIVTEILKDGRNL
                     SRKSLCAKLLCRLEHATGEEEQKHYNALIGLLFE"
     gene            1174..2385
                     /gene="bluF"
                     /locus_tag="ACHY1N_005033"
     CDS             1174..2385
                     /gene="bluF"
                     /locus_tag="ACHY1N_005033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blue light-responsive regulator BluF"
                     /protein_id="HFS4047172.1"
                     /translation="MLTTLIYRSHIRDDEPVKKIEEMVSIANRRNMQSDVTGILLFNG
                     SHFFQLLEGPEEQVKMIYRAICQDPRHYNIVELLCDYAPARRFGKAGMELFDLRLHER
                     DDVLQAVFDKGTSKFQLTYDDRALQFFRTFVLATEQSTYFEIPAEDSWLFIADGSDKE
                     LDSCALSPTINDHFAFHPIVDPLSRRIIAFEAIVQKNEDSPSAIAVGQRKDGEIYTAD
                     LKSKALAFTMAHALELGDKMISINLLPMTLVNEPDAVSFLLNEIKANALVPEQIIVEF
                     TESEVISRFDEFAEAIKSLKAAGISVAIDHFGAGFAGLLLLSRFQPDRIKISQELITN
                     VHKSGPRQAIIQAIIKCCTSLEIQVSAMGVATPEEWMWLESAGIEMFQGDLFAKAKLN
                     GIPSIAWPEKK"
     gene            2590..3321
                     /gene="bluR"
                     /locus_tag="ACHY1N_005034"
     CDS             2590..3321
                     /gene="bluR"
                     /locus_tag="ACHY1N_005034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor BluR"
                     /protein_id="HFS4047173.1"
                     /translation="MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDE
                     EDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDDWSRLQEEMMSILRMANPAKLRA
                     RIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAATSLFEMRRK
                     PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIESPRPELFPTQTLIVWTGM
                     APTRRQNELLQHWGEQGYKVIFHAP"
     gene            3542..3946
                     /locus_tag="ACHY1N_005035"
     CDS             3542..3946
                     /locus_tag="ACHY1N_005035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 domain-containing protein"
                     /protein_id="HFS4047174.1"
                     /translation="MDQVVVFQKMFEQVRKEQNFSWFYSELKHHRIAHYIYYLATDNI
                     RIITHDDTVLLLRGTRNLLKVSTTKNPAKIKEAALLHICGKSTFREYCSTLAGAGVFR
                     WVTDVNHNKRSYYAIDNTLLYIEDVENNKPLI"
     gene            3999..4109
                     /locus_tag="ACHY1N_005036"
     CDS             3999..4109
                     /locus_tag="ACHY1N_005036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047175.1"
                     /translation="MGIKVQRLSLWMINTVLLLLPINNHHANTIKLIFEM"
BASE COUNT         1298 a          894 c          851 g         1311 t
ORIGIN      
        1 taataattag aagttacata tcatcagctg tgtatcgcaa cacgatttcc agtgtttttc
       61 taatcacatc agctttgaga atatcacttg ttgtttccag ggagtgtatc agacttaaga
      121 taatattttt attattaaca ttatcgcctg aaagcattaa attggtgaca gcctgcccta
      181 acactgctga ctcttcttct aacaaattac ccgaactgcg aaagtaactt gctaacgctt
      241 tatcagttat tgcattatga attgtagtat cttcaagcat ggtaacctct catcttactt
      301 atgaaatttt aatgtattct gtttattttc ttaccattga acatactttt attgtcagct
      361 gtcgctgttc ttcggtttgg tcctcctgaa tcactattgc taaaatcacg aattatgctg
      421 tcaattaaat cgcgtcggaa agcatcttcc tcagccgatt tcattacgag taattgctta
      481 ataagagtct gcaatgaaaa atttatcttc atgcgcagta tctggatcac cgcctggcca
      541 gtaatttcat attttatacg ttcattatca gatgtcttca taacgacttc atagctaacc
      601 tgttaaataa tcaggctgtt gcattattca aaaagcaacc caattagtgc attataatgt
      661 ttctgttcct cttccccagt cgcgtgttcc agtcggcaaa gaagtttggc acaaagcgac
      721 tttcgactca gattacgtcc atctttcaaa atctcagtca caatttcccc gagagtttcc
      781 tgctgagtag gcaagttagc ttttgcaaag taacgagtga ttgctcccgc agaatctaaa
      841 gtcactgaat tttgatgcat gctacgcctc tgttaaaaat gttaatcaat gttaagtgag
      901 gtaacaatag caaacttgta cgaaatatgt gtacagaatg ataaattaat tttttgcaat
      961 tagtgctaat gcatataaaa caatgtgtta tgataaaaca tattgcatca tttacctgac
     1021 aatctataca agatttttcg ccaactagtg ttcaactttt tccatttttt atcaatgtaa
     1081 agaaacggtt atgttttggt attaaaagaa agacacaaga agatatgtct gttaccgtct
     1141 tactctcgcc tcacccatta ccctggattg ttaatgctta ccacccttat ttatcgtagc
     1201 catatacgtg acgacgaacc tgtcaaaaaa atcgaagaaa tggtttcgat agcaaatcgc
     1261 aggaacatgc agtctgacgt aacagggatc ttactgttta atggttctca ttttttccag
     1321 cttctggaag gtccggaaga acaggttaaa atgatatatc gggctatatg ccaggatcca
     1381 cggcactata atattgttga gctgctgtgc gattacgcgc ctgctcgccg ttttggcaaa
     1441 gcgggaatgg aattatttga tttgcgcctg cacgagcgag atgacgtttt acaggccgta
     1501 ttcgacaaag gcacatcaaa atttcagcta acttatgatg acagagcgct acaatttttt
     1561 cgtacttttg tccttgcaac cgaacaatca acctatttcg agatccctgc cgaagactcc
     1621 tggcttttta tcgctgacgg atctgataaa gaacttgatt cctgtgccct ttcaccaact
     1681 ataaacgacc actttgcctt tcatcctatt gtcgatccct tatcgcggcg gataatcgct
     1741 tttgaagcca ttgtgcaaaa aaatgaagat agcccatcag ccatagcggt tgggcagcgt
     1801 aaagacgggg aaatctacac agcggatctc aaaagtaagg cgcttgcatt cacgatggca
     1861 cacgcacttg agctcggtga taaaatgatt tcaatcaatc tattacctat gaccctggtt
     1921 aacgaacctg acgcagtctc ttttttactt aatgaaataa aggccaatgc tctggtgcct
     1981 gaacaaatca tcgttgaatt tactgaaagt gaagtcatat ctcggtttga tgagtttgcc
     2041 gaagcgatta aatcgctaaa ggctgctggt atcagtgtag caattgatca ttttggcgca
     2101 ggttttgctg gtttgttact cctgtcacgc ttccagcctg acagaattaa aatcagtcag
     2161 gaattgatta ccaatgttca taaaagtggg ccacggcagg caattattca ggcgatcata
     2221 aaatgctgta catcacttga aattcaagtc agtgctatgg gcgtggcaac accagaagag
     2281 tggatgtggc ttgaatccgc aggaattgag atgtttcagg gagatctgtt tgctaaagct
     2341 aaattgaatg gtatcccttc catagcgtgg ccagagaaaa aataattttc agcacattct
     2401 ttcacatgat ttcagtaaat catcgtgaaa atgaatacgt tacgtttaaa tttaatccac
     2461 attaaaaata atgtttcatc caatttagct gaaatcttat ttatactttg tacaatttta
     2521 gcgtatattg tacaaagtat tattgggtcg tgtacaggcg acggagattt gtgaccgcaa
     2581 ggaggaattg tggcttatta cagcattggt gatgttgctg aacgttgcgg gattaatcct
     2641 gtcactctcc gggcctggca acgccgctac ggtttgttaa aaccacagcg cagtgaaggc
     2701 ggacaccgac tctttgatga agaagacata caacgcatcg aagagatcaa gcgttggata
     2761 agtaatggcg tccctgtagg caaagttaaa gcattactgg aaaccaccag ccaggatacg
     2821 gaagatgact ggagccgcct gcaagaagag atgatgtcaa ttcttcgcat ggctaatcct
     2881 gccaaactac gcgcgagaat tatttcactg ggtcgagagt acccagtaga tcaattgatt
     2941 aatcatgttt accttcctgt tcgccagcgt ctcgtgcttg atcacaacac ctcccgcatt
     3001 atgagcagta tgtttgacgg cgcattaatt gaatacgcag caacctcgct tttcgaaatg
     3061 cgccgtaagc ccggtaaaga agccattctg atggcgtgga atgttgaaga gagagcacga
     3121 ttgtggctgg aagcatggcg tttatcattg tcaggatggc acatttctgt tcttgctgat
     3181 cccattgaat cgccgcgccc ggaactgttc ccgacgcaaa cattgattgt ctggacaggc
     3241 atggcaccaa cgagaaggca aaacgaactt ttacaacact ggggtgagca aggttataaa
     3301 gtcatctttc atgcccccta atttcacctt tatcccgccc cttagacaga atgttataat
     3361 ctgaacccac aacagcgttt gtaccggagc tggtccgttg caaaatgctc accgggagaa
     3421 ttcagatatt ccctctatca cactctgtac atatcacagc caaaggacag accagattga
     3481 agtggtaaaa ccgatcgtgc acactacgca gtctcacaac taacaagagg ttattatcct
     3541 gatggatcag gtcgttgttt ttcaaaagat gtttgagcaa gtgagaaaag agcaaaactt
     3601 ctcctggttt tattcagaat taaaacatca ccgtattgca cattacattt attatctggc
     3661 tacggataac atcagaatta ttactcacga tgacacggtt ttgttattaa gaggaaccag
     3721 gaacctgtta aaagttagta cgaccaagaa ccctgctaaa ataaaagagg ccgcattgct
     3781 tcatatttgc ggaaaatcta catttcggga atactgttca acactagcag gcgcgggcgt
     3841 tttccggtgg gttactgatg ttaatcataa caaacgcagt tactacgcca ttgataatac
     3901 gcttttatat attgaagatg tagaaaataa taaaccatta atctagctaa agttggatgc
     3961 ttaagaaatg cttcataatt cagtaaggca ttagcataat gggaataaaa gtacagagac
     4021 tatccctatg gatgataaat actgtccttt tattgctacc cataaataat caccatgcca
     4081 atactatcaa attgatattt gaaatgtgat cacttgactt tctatacgtt attttataac
     4141 ggttaatata tttataaaaa caacgggtgt gccatacgcc cgtttcaata cttaacgcac
     4201 atgtgttttg gtttagtcat catccagtta tatgtatttt agccaggaac aggttaaacc
     4261 tttcctatat aactcaaaaa ttgaaacctt attctcatgt catgcttata ttcattatta
     4321 tcgttatata aaaaggcaac cataatgttt agca
//
LOCUS       DAZUDJ010000174         4301 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.177, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000174 DAZUDJ010000000
VERSION     DAZUDJ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4301
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.177"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..567
                     /gene="nleB"
                     /locus_tag="ACHY1N_005037"
     CDS             <1..567
                     /gene="nleB"
                     /locus_tag="ACHY1N_005037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector arginine
                     glycosyltransferase NleB"
                     /protein_id="HFS4047176.1"
                     /translation="QESYPASERDNYLLGLLREELKNIPEGKDSLIESYAEKREHTWF
                     DFFRNLAMLKAGTLFTETGKTGCHNISPCSGCIYLDADMIITDKLGVLYAPDGIAVHV
                     DCNDEIKSLENGAIVVNRSNHPALLAGLDIMKSKVDAHPYYDGLGKGIKRHFNYSSLH
                     DYNAFCDFIEFKHENIIPNTSMYTSSSW"
     gene            616..1290
                     /gene="nleE"
                     /locus_tag="ACHY1N_005038"
     CDS             616..1290
                     /gene="nleE"
                     /locus_tag="ACHY1N_005038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector cysteine
                     methyltransferase NleE"
                     /protein_id="HFS4047177.1"
                     /translation="MINPVTNTQGVSPINTKYAEHVVKNIYPEIKHDYFNESPNIYDK
                     KYISGITRGVAELKQEEFVNEKARRFSYMKTMYSVCPEAFEPISRNEASTPEGSWLTV
                     ISGKRPMGQFSVDSLYNPDLHALCELPDICCKIFPKENNDFLYIVVVYRNDSPLGEQR
                     ANRFIELYNIKRDIMQELNYELPELKAVKSEMIIAREMGEIFSYMPGEIDSYMKYINN
                     KLSKIE"
     gene            1668..2645
                     /locus_tag="ACHY1N_005039"
                     /pseudo
     CDS             1668..2645
                     /locus_tag="ACHY1N_005039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041206064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3168..>4301
                     /locus_tag="ACHY1N_005040"
     CDS             3168..>4301
                     /locus_tag="ACHY1N_005040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001239084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcdB toxin N-terminal helical domain-containing
                     protein"
                     /protein_id="HFS4047178.1"
                     /translation="MRLPEKVLFPPVTSGLSGQEKQKKPKSITGFQENYQRNIRPIKT
                     ASEARLRFFDKMVSKENSLEDVVSLGEMIQKEIYGHEQRTFSPVHHTGNWKSSLLHNA
                     LLGLANVYNGLRETEYPNTFNRDGIKSTNSFRDNLLTKTRTPRDNFEEGIKHPEHATI
                     PYDNDNESNKLLKAGKIAGNNNELLMEIKKESKSDHQIPLSDKFLKRKKRSPVAEDKV
                     QNSLTPENFVQKISLSDELKTKYANEIIEIKRIMGEYNLLPDKNSRNGLKLLQKQADL
                     LKIIMEDTSVTENIFKNIEMAIADIKKEYYSHTVDIEKNIHAIWVAGSPPESISDYIK
                     TFLKTYKEFTYYLWVDEKAFGAAKFTSVLKQIAFDLACRTIQQN"
BASE COUNT         1451 a          795 c          898 g         1157 t
ORIGIN      
        1 caagaatcat accctgccag tgagagggat aattatctgt taggcttatt aagagaagag
       61 ttaaaaaata tcccagaagg taaggactct ttgattgagt catatgcaga aaaaagagaa
      121 catacttggt ttgatttttt caggaatttg gccatgttga aggctggaac tttgtttaca
      181 gagacgggaa aaactggatg ccataacata tcgccctgta gcggatgtat atatcttgat
      241 gccgacatga ttattaccga taaattagga gtcctgtatg ctcctgatgg tatcgctgtg
      301 catgtagatt gtaatgatga gataaaaagt cttgaaaatg gtgcgatagt tgtcaatcgt
      361 agtaatcatc cagcattact tgcaggcctc gatattatga agagtaaagt tgacgctcat
      421 ccatattatg atggtctagg aaagggtatc aagcggcatt ttaactattc atcgttacac
      481 gattataatg ctttttgtga ttttattgaa tttaagcatg aaaatattat accgaatacc
      541 agtatgtata ccagcagttc atggtaagtc ttccggttgt ggttgaaaaa tatcgttctt
      601 taggtataga ttcagatgat taatcctgtt actaatactc agggcgtgtc ccctataaat
      661 actaaatatg ctgaacatgt ggtgaaaaat atttacccgg aaattaaaca tgattacttt
      721 aatgaatcac ccaatatata tgataagaag tatatatccg gtataaccag aggagtagct
      781 gaactaaaac aggaagaatt tgttaacgag aaagccagac ggttttctta tatgaagact
      841 atgtattctg tatgtccaga agcgtttgaa cctatttcca gaaatgaagc cagtacaccg
      901 gaaggaagct ggctaacagt tatatccgga aaacgcccaa tggggcagtt ttctgtagat
      961 agtttataca atcctgattt acatgcatta tgtgagcttc cggacatttg ttgtaagatc
     1021 ttccctaaag aaaataatga ttttttatac atagttgttg tgtacagaaa tgacagccct
     1081 ctaggagaac aacgggcaaa tagatttata gaattatata atataaaaag agatatcatg
     1141 caggaattaa attatgagtt accagagtta aaggcagtaa aatctgaaat gattatcgca
     1201 cgtgaaatgg gagaaatctt tagctacatg cctggggaaa tagacagtta tatgaaatac
     1261 ataaataata aactttctaa aattgagtag agaagctcag ccacttgtgt aggggggcta
     1321 aaattaattc tatttcatta tatgagaaca ccaataagaa taataatatt tgatcacaac
     1381 tgaagatgct ttttacaatg aagaattatt gttaaaaaac gctttgttga atcaaccgaa
     1441 ctgttgctga gttgcaggat cacatcacgt attttcctga aaacgcaggc tgcttagtag
     1501 caaagcagaa gttcaaaatc accaactaaa tagctgcgcc gaatagtaga tcaatgaaag
     1561 ggaactcagc ccggattgtg cgatctgatc aatcgccaaa aatccccccc taaccggact
     1621 gagcgatgcc gatcatagca ccaattcccc gcgacgaatg acgcctgatg caaaaagcaa
     1681 tctataaaac tcacgataaa aattatgccc gcaggctgac cgccatgctg atgctgcacc
     1741 ggagcgctcg cgtcagtgac gttgccagaa cgctctgctg cgcccgttcc tccgtcaggc
     1801 gctggattaa ctggttcacg ctgtcgagtg ttgaaggtct gaaatcatta cccgcaggac
     1861 gttcccgccg ctggccgttt gagcatatct gcacattgtt tcgtgaactg ataaaacact
     1921 ctcccggata ttttggctat cagcgttcac gctggagtac agaactgctg gcaataaaaa
     1981 tcaacgagat aaccgagtgc cagttacatg ccggaaccgt tcgccgctgg ttgccattag
     2041 tcgggcttgt gtggcgcagg gctgcgccaa ccctgcgtac ccgtaacccg cataaagcag
     2101 caattcacaa agcactggac gaatgtagtg cggagcatcc ggtcttttat gaagatgaag
     2161 tgtatatcta tcttaatccc aaaaccggtg cggactggca acttcgcaga cagcaaaaac
     2221 atgtggtaac accggggcag aatgaaaaat actatctggc tggtgcttta catagtggaa
     2281 cgggcaaagt cagctatgtg ggtggcaaca gcaaaagctc agccttattt atcagtctgt
     2341 tgaaacatct gaaattgaca taccgacggg ataaacctat cacgctcata gtggacaact
     2401 acatcatcca taaaagtcgg gaaacacagc gctggctgaa agaaaatccg aagttcagag
     2461 tgatttatca gccagtttac tcgccgtggg tgaatcatgt tgagcggtta tagcaggcgc
     2521 ttcacgatac gataacgcgc aatcatcagt gccgttcaat gtggtaactg cttaaaaagg
     2581 ttcattattt tatggaaacc gtgagcccat tccccggtgg taaatatggg ctgttaaaag
     2641 tgtagcggta ttcggcgcag ctatttagga tggtcaggtc gcagaagttc tgtgccacta
     2701 cagtgcgtgt actaaacaaa atgacgaggg cacgaatgtc ataatacgtg cgtattacct
     2761 gcagtagcta ccaactgagg gggcttatcc caaacctgat ttattcaaca aagctggact
     2821 ggacttatcc ttactctgaa ttattttcca gacatatgca tcatgtactg gctcgcttgg
     2881 ttcaggaaat acaggagcaa atctacagct attagattta ttcctatttg tatgcaaagt
     2941 cgcattgcat aatgcggagc tatgttacag atacgcctga cgtgcgtagt aaaattataa
     3001 agcaacatat atatacaagg agaaaccgag aaaaataaat gagtcgtatg ttgggtagca
     3061 tcgagataaa tattttttta tcacattagc accttggtta agggtgttaa taataagatt
     3121 ttctcactta ttaaaacata aataattttt taagcggaaa tgtaattatg agactgccag
     3181 agaaagttct ttttcctcct gtcactagtg gcctgtcagg gcaggaaaaa caaaaaaaac
     3241 cgaagagcat taccggattt caggaaaatt atcaacgcaa tatcaggcca atcaaaacag
     3301 catcagaagc ccgactacgc ttctttgata aaatggtttc gaaagaaaac tctctggaag
     3361 atgttgtttc tttaggtgaa atgattcaga aggaaattta tgggcatgaa caaagaacat
     3421 tttcaccagt tcatcataca ggtaactgga aatcatcatt gttacacaac gcgctccttg
     3481 gtctggcaaa tgtttataat ggcttacggg aaacagaata ccctaacact ttcaacagag
     3541 atggtataaa aagtactaac tcttttagag ataacttatt gacaaaaaca agaactccca
     3601 gagataattt tgaggaagga ataaaacatc ctgaacatgc aacaatacca tatgacaacg
     3661 acaatgaaag taataaattg ctaaaagcag gaaagatagc tggtaacaat aacgagctgt
     3721 tgatggaaat aaaaaaggaa tccaaaagcg accatcaaat ccccctgtca gataagttcc
     3781 tgaaaaggaa aaaacggtct cctgtagctg aagataaagt tcaaaactcg ttaacaccag
     3841 aaaattttgt tcagaaaatt tcacttagtg atgagcttaa aacaaaatat gcaaatgaaa
     3901 ttatagagat aaaaagaata atgggagaat acaatctttt accggataaa aacagtcgta
     3961 atggtctaaa acttctacag aagcaagctg atttactaaa aataatcatg gaggatacct
     4021 ctgttacaga aaatatcttt aaaaacatag agatggctat agcagatata aaaaaggagt
     4081 actattcgca tacagttgat attgagaaaa atattcatgc catatgggtt gcgggttccc
     4141 cacctgaaag catctcggac tatattaaga cttttctcaa aacctacaaa gagtttactt
     4201 actatctttg ggttgatgaa aaagcatttg gagccgcgaa atttaccagt gtcttaaaac
     4261 aaattgcatt tgatttagca tgcagaacta tacagcagaa t
//
LOCUS       DAZUDJ010000175         4225 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.178, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000175 DAZUDJ010000000
VERSION     DAZUDJ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4225
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.178"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..360)
                     /locus_tag="ACHY1N_005041"
     CDS             complement(<1..360)
                     /locus_tag="ACHY1N_005041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShET2/EspL2 family type III secretion system
                     effector toxin"
                     /protein_id="HFS4047179.1"
                     /translation="MPIINKSASNYVEYISKNNPPYLSKKRDASINLNGKVSDCNGEI
                     IWCRHIASYWSEFFCSNSGKIDYETFSSPQLLSKAIVIQENKGTNNIKGDVYFVENES
                     WGSVIYNLFLQLEKENKS"
     gene            complement(351..914)
                     /locus_tag="ACHY1N_005042"
                     /pseudo
     CDS             complement(351..914)
                     /locus_tag="ACHY1N_005042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178393.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS481 family transposase"
     gene            complement(1148..1825)
                     /locus_tag="ACHY1N_005043"
     CDS             complement(1148..1825)
                     /locus_tag="ACHY1N_005043"
                     /inference="COORDINATES: protein motif:HMM:NF033590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HFS4047180.1"
                     /translation="MWHYLHYKVSRGKPHAECDAKRRAGSPPGPDAHQLQRSQHKKSR
                     QQRPGALAHVCLLRGAGEDGACWYPLTSEKVASAADARRIVSHYEQRWLIEEYHKAWK
                     SGGTCVESLRMQTRDNLERMVVIAVRVLGLRQGSISEETQNDSCEKILTPTEWKLLWV
                     KLEGKQLPAQTPTLKWACLKLAKLGRWHDSKRTSSPGWVVMWDGWFRHQDMAEGYLVM
                     KSLDQEI"
     gene            2023..3642
                     /locus_tag="ACHY1N_005044"
     CDS             2023..3642
                     /locus_tag="ACHY1N_005044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEc38 family transposase"
                     /protein_id="HFS4047181.1"
                     /translation="MGNSMHSLKTLLQLPCGWRCSRQIISSDGITLHLHGKRKKAQCP
                     ECFKRSDSVHSCRRRRIQHLPCSGHTLWLVFSVRHWYCRNPACSRKIFAGSLAPFAGS
                     HQQSSQALQNLQRQLGLIAGGEAGKRAATAVGLRCSADTLLRRVINTPETKQSGAPHV
                     GIDEWAWHRGHRYGTLIVNLDTHRPLVLLPGRDQRTLATWFRKYPEIQVVSRDRSGVY
                     ATAAREGAPQARQVADRWHLLKNIGDALERMMYRHIPLIRLVASELSPKKSPDPEPSV
                     PAASLRRPERLKQQTRKKRHQRWTEVMALHNKECSFREISRITGLSRVTVSRWVRSGT
                     FPEMSTRPPKRGLLDPWREWLKEQRESSNYNASRIWREMVARGFTGSETIVRDAVAKW
                     RKGWNPPVTTAVRLPSVSRVSRWLMPWRITRDEENYASRFISLMCEKEPELKIAQQLA
                     LEFYRILKTQNKSQLSSWFNRVHESGSAEFRRVAAGMEADAAAICEAISSRWSNGVVE
                     GHVNRLKMLKRQMYGRAGFELLRQRVMSPLA"
     gene            3639..>4225
                     /locus_tag="ACHY1N_005045"
     CDS             3639..>4225
                     /locus_tag="ACHY1N_005045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HFS4047182.1"
                     /translation="MKISTQVAEEPLSVVDTDDIFLLKQRLAEQEALIHALQEKLSNR
                     EREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLHKESDTLTGRVYDPAVQR
                     PLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTTEQLELMRSAFRVIR
                     TVREKHACTQCDAIVQAPAPSRPIERGIARPGLLAR"
BASE COUNT         1043 a         1067 c         1008 g         1107 t
ORIGIN      
        1 agatttattc tctttctcaa gttgaagaaa aaggttatat ataacgcttc cccaagattc
       61 attttcaaca aaatacacat cacccttaat attatttgtc cccttgtttt cctgaattac
      121 aatagctttg cttaataatt gaggggatga aaatgtttcg tagtctatct ttcctgaatt
      181 actacaaaaa aactcactcc aatatgatgc tatatgtcga caccatatga tttccccatt
      241 gcaatcacta acctttccat ttagatttat actggcatct ctcttttttg ataaataagg
      301 gggattgttt tttgaaatat attcaacata atttgatgcc gatttgttta ttattggcat
      361 atgtttgtat cctttctata aattttccgc ctgacagtgg aaataatata ttctactgat
      421 ttttgtagtt taaacgattt atgaagaatt ttactgttgt acagtaccag atactcagcc
      481 agtttcagat tgaacatatt cagctattca aagagcaatt cttcattaaa ctcaataaat
      541 tgttccctca gtgttcggtt aaaatgctca cttatggcat ttattttcgg cgtatagaga
      601 taagtccata cgaacccgac ggtggcttcc tgtagcgttt tgtcgaattt tcccgagaac
      661 tctttgccca tcatcagtga tgatctggtt gataccaaca aggaacaact gggctacaca
      721 gcagaagaaa tgcctgatga tatcactttt aagcgatagt acggccagag agtagttgct
      781 gtgttcgtcg agcatggtaa tgaaataacg gtacagctcg ccattctgag ctcaatagta
      841 tccatgccac tgagcttaca ggtctttatc gggcgatagt gctttattct tcggggcttt
      901 gtggatgatt tttcgaaatg ttcatgatag ttaggtaaag ctaccgcata tcatttgcaa
      961 aatgacagat agatatactt caatttgaat cttaacaatt agtatgggaa tgctgtcaat
     1021 cctctgtatg cgtccaccac atattgaaat ttttgttctc taatatattc cacgggcgtc
     1081 aagagtgtga ggcctgtgct gttatacagc accagacgtt gtcccccatc tttgacctgt
     1141 ctcttgatca gatctcctga tcaagagact tcatcaccag gtaaccctca gccatatcct
     1201 gatgtctgaa ccagccatcc cacataacta cccaaccggg gctgcttgtg cgtttgctgt
     1261 catgccatcg ccccagttta gccagtttca aacaggccca tttcagggtc ggtgtttgcg
     1321 ctggaagctg ctttccttcc agcttaaccc acagtagttt ccactctgtc ggcgtcagta
     1381 ttttctcaca gctgtcattt tgtgtttctt cactgatact tccctgccgc aggcccagca
     1441 cccgcaccgc gataaccacc atgcgctcaa ggttatcccg ggtctgcatt cgcagcgatt
     1501 ccacacatgt accaccactt ttccacgctt tgtggtattc ctctatcagc cagcgttgct
     1561 cgtaatggct gacgatacgt cgcgcatcgg cggcactcgc cactttttct gatgtcagcg
     1621 gataccagca ggctccgtcc tctcctgctc cccgcaacag acatacgtga gcgagagcgc
     1681 ctggccgctg ttgtcgggat tttttatgct gacttcgctg taactgatga gcatccgggc
     1741 ctggcgggct gcccgcccgc ctttttgcat cacattcagc gtgtggcttc ccgcggctga
     1801 ctttataatg caggtaatgc cagatatccg cttcccggtc acagacagtg attacctgtt
     1861 tctgtatctc ccccagccgt tcggccatgc gctccgaagc ctgctgccag cggtaacttt
     1921 ctttttctgt cacgaacggt gcaatagtgg ttcttccgca acttgggtgg aagaaaatgg
     1981 atgaaacttt ctggtgaaca aagatctaag ctgttttaag tcatgggcaa ctcaatgcac
     2041 tctcttaaga cacttctaca gttaccttgc ggatggcgat gcagtcgaca aattattagc
     2101 tctgacggta taaccctcca tctccacgga aaacgcaaaa aagcacaatg tcctgaatgc
     2161 tttaagcgta gcgactctgt tcatagttgt cgtcggcgcc ggatacagca tctaccctgc
     2221 tcaggacata cgctatggct tgtattttcc gtccgccact ggtactgccg taacccggct
     2281 tgttcacgta aaatttttgc cgggtcgctt gctcccttcg ccggttcaca ccaacagtct
     2341 tcacaggcgt tacaaaattt acaacgtcaa ctgggattaa tcgccggagg tgaggccggg
     2401 aaacgggcag caacggcagt ggggctccgt tgcagtgctg atactctcct tcgcagggtt
     2461 atcaataccc cggagacgaa acagtcaggc gcgcctcatg tcggtattga tgagtgggcg
     2521 tggcatcggg gccaccgtta cggtacgtta atcgtcaatc ttgatactca ccgtcccctc
     2581 gtcctgcttc ccggccgtga tcagcgtacg ctggcgacct ggttcagaaa atatccggaa
     2641 atacaggttg tctcgcgtga tcgcagtgga gtctatgcga cagcagcacg tgaaggtgca
     2701 cctcaggcca gacaggtggc cgatcgatgg catctgctaa aaaatattgg cgatgcgctt
     2761 gaacgaatga tgtacagaca tatacctctg atacgtcttg ttgccagtga gttgtcacca
     2821 aagaaatcac ctgatccaga accatctgtg cctgcagcat cgctccgtcg tccggaacgc
     2881 ctaaaacaac aaacccgcaa aaaacggcat cagcgttgga cagaggttat ggccctgcat
     2941 aacaaggaat gtagtttcag ggaaatatcc cgtattacag gcctgtcgcg tgtgacagtc
     3001 agtcgctggg tgcgttcagg aacattccct gaaatgtcaa cccgacctcc aaagcgaggg
     3061 cttctggacc catggaggga gtggttaaaa gagcaacgag aaagtagtaa ttataacgcc
     3121 agccggatat ggcgggaaat ggtggcccgg ggatttacag gcagtgaaac catcgtcagg
     3181 gatgcggttg ccaaatggcg taaaggctgg aacccaccgg ttactactgc cgtcagactt
     3241 ccttcagtgt cccgggtaag ccgctggttg atgccctgga gaataaccag ggatgaagaa
     3301 aattatgctt cccgatttat tagtctgatg tgtgaaaaag aacctgagct gaaaatagcg
     3361 cagcaactgg cactcgagtt ctaccgtatt ctgaaaaccc aaaataaatc acagctaagc
     3421 agttggttca atcgagtcca cgaaagcggt tcagcagaat ttcggcgcgt ggcggcgggg
     3481 atggaagctg atgctgcagc tatatgtgag gcaatcagta gtcgctggag taatggtgtt
     3541 gtcgaaggtc atgtaaatcg cctgaagatg ctgaaacgcc agatgtatgg tcgagcagga
     3601 tttgaactac tcaggcagag ggtaatgagt ccactggcat gaaaatctcc acccaggttg
     3661 cggaagagcc actttccgtc gttgacactg acgacatctt cctgctgaaa cagcgcctgg
     3721 ccgaacagga agcgctgatc cacgccctgc aggaaaagct gagcaaccgg gagcgcgaaa
     3781 tagaccatct gcaggcgcag ctggataaac tccgccggat gaacttcggc agtcgttccg
     3841 aaaaagtctc ccgccgtatc gcacaaatgg aagccgatct gaaccggctt cataaagaga
     3901 gcgatacgct gactggtagg gtgtatgacc cggcagtaca gcgtccgttg cgtcagaccc
     3961 gcacccgtaa gccgttccct gaatcactac cccgtgacga aaagcgactg ttgcctgcgg
     4021 cgccgtgctg cccgaactgc ggcggttcac tgagctatct gggcgaggat accaccgaac
     4081 agctggagtt gatgcgtagc gcctttcggg ttatccggac ggtacgggaa aaacatgcct
     4141 gtactcagtg cgatgccatc gtgcaggcac ctgcaccttc gcggcccatc gagcggggta
     4201 tcgccagacc ggggctgctg gcccg
//
LOCUS       DAZUDJ010000176         4199 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.179, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000176 DAZUDJ010000000
VERSION     DAZUDJ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4199
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.179"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..227)
                     /locus_tag="ACHY1N_005046"
     CDS             complement(<1..227)
                     /locus_tag="ACHY1N_005046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HFS4047183.1"
                     /translation="MTFKHYDVVRAASPSDLADALAQKIREGWQPYGGPFSSYTDDGA
                     ALIQAIVAEGDVSTPVVVKPTGGEGAVISAT"
     gene            468..602
                     /locus_tag="ACHY1N_005047"
                     /pseudo
     CDS             468..602
                     /locus_tag="ACHY1N_005047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309987.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(707..783)
                     /locus_tag="ACHY1N_005048"
     tRNA            complement(707..783)
                     /locus_tag="ACHY1N_005048"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(747..749),aa:Arg,seq:tct)
     gene            complement(797..873)
                     /locus_tag="ACHY1N_005049"
     tRNA            complement(797..873)
                     /locus_tag="ACHY1N_005049"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(837..839),aa:Arg,seq:tcg)
     gene            complement(881..956)
                     /locus_tag="ACHY1N_005050"
     tRNA            complement(881..956)
                     /locus_tag="ACHY1N_005050"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(921..923),aa:Ile,seq:cat)
     gene            complement(985..1698)
                     /locus_tag="ACHY1N_005051"
     CDS             complement(985..1698)
                     /locus_tag="ACHY1N_005051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4047184.1"
                     /translation="MVVVCSVIMVCSPINIFLEKDTLSLKPGSVVLATKCIRALFLMH
                     YGKVKIFDINHSIVSQYLEIQHKLTRTHLTDVPLYLSLEPNNPALAEALITSQRFSGD
                     TTDMFLMMACLSLFESDERILLFLSGCLSSISAKVRAIIQTDISASWTLGAIALRLHM
                     SESLLKIKLKNEGHMFSRLLLEERMRVAVNMLCSRHGYGQAVAEKCGYSSWSYFISVF
                     HRYYGFPPDRYVSRQGLDY"
     gene            complement(1836..2033)
                     /locus_tag="ACHY1N_005052"
     CDS             complement(1836..2033)
                     /locus_tag="ACHY1N_005052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFS4047185.1"
                     /translation="MLKQQDMTETARVVFDELSVTEPATVGEIAQNTYLSRERCQLIL
                     TQLVMAGLADYQCGCYRRLQS"
     gene            complement(2320..3138)
                     /locus_tag="ACHY1N_005053"
     CDS             complement(2320..3138)
                     /locus_tag="ACHY1N_005053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HFS4047186.1"
                     /translation="MWIVLVLSLSTLSWHKVVAFSLLTVSVVLAVLNDIIDWSVLFFV
                     ATIVFFIILKFNWKYNAWAKSIYEVGIVLSAIALSFHLWPGFHNPVVLNSVTVGPQST
                     PYTMYFNFDKALVPFLLVLCTSSLFKKEVKSEVSLWKWGALSLSVPLILFLAVFFGGL
                     KPEIHFPEWLPEFILANLFFVSLAEESLFRGYIQSRLSEVTSPLVALIVAALLFGFYH
                     YSGGALLVLFATLSGVVYGLSWMWSGRLWVATLFHFGLNLCHLLFFTYPFLKHN"
     gene            complement(3290..3661)
                     /locus_tag="ACHY1N_005054"
     CDS             complement(3290..3661)
                     /locus_tag="ACHY1N_005054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0060567 - negative regulation of
                     termination of DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator Q family protein"
                     /protein_id="HFS4047187.1"
                     /translation="MARDIQMVLERWGAWAANNHEDVTWPSIAAGFKGLIPTKVKSRP
                     QCSDDDAMIICGCMARLNKNNQYLHDLLVDYYVGGMTFMALARKHRCSDGLIGKRLYK
                     AEGIIEGMLMALNVRLDMDMR"
     gene            complement(3651..4022)
                     /locus_tag="ACHY1N_005055"
     CDS             complement(3651..4022)
                     /locus_tag="ACHY1N_005055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFS4047188.1"
                     /translation="MRIEFVLPYPPTVNTYWRRRGSTYFVSKAGERYRRAVALIVRQQ
                     RLKLSLSGRLAIKIIAEPPDKRRRDLDNILKAPLDALTHAEVLIDDEQFDEINIVRGQ
                     PVPGGRLGVKIYEIRGGNDGA"
     gene            complement(4035..>4199)
                     /locus_tag="ACHY1N_005056"
     CDS             complement(4035..>4199)
                     /locus_tag="ACHY1N_005056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HFS4047189.1"
                     /translation="GMGTKSHDIFTLPLCREHHNELHADPLAFEEKHGSQVDLIFRFL
                     DHAFATGVLG"
BASE COUNT         1320 a         1062 c          795 g         1022 t
ORIGIN      
        1 ctggtggcgc tgattactgc accttctcca cctgtcggct tcaccacaac aggtgtgctc
       61 acatcacctt ctgcgacaat cgcctgaata agtgctgcgc catcatccgt atacgaagaa
      121 aacggcccgc cgtatggttg ccatccttca cgaatttttt gagcaagtgc atcagcaagg
      181 tctgacggcg acgccgccct gacaacatca taatgtttaa atgtcattat tcctcccggc
      241 cgggatagtg tattaaatca gatatggagt gggctgtagt ccggaagcct gaatgacaca
      301 cggggactac agcccaagaa atgaaaaaag gccacgcagt tgcgcagcct gataaaccct
      361 ggttaaaatc cacacgataa caacacaaca atatcagtat ctcatgctat tgcccgaacc
      421 cattcgggca ttttttaccc ataaaaaatg cccctccgga gaggggcatg tttgcatgca
      481 cattcttttt cttgcatggt gccgggtgcc tcccggtgaa ttcagtacca gcacctgaat
      541 ccgcgattat cccatatacc tactcgctga ttgcccctcc gcacaggggg attcaccatg
      601 ccagtttctt ttaacaaact ccccgcaaac cagacaacag tcaaccgcct gaattgtgag
      661 acatttaaaa aaaaggcccg caaaagcgag ccagggaaaa taagtgtggc gcgttgtact
      721 ggattcgaac cagtgaccga ttgcttagaa ggcaattgct ctgtccggct gagctaacaa
      781 cgcaggatac agataatgga ccgccttcgg ggacccgaac tccgcgcaac cagcttcgaa
      841 agctggcgct ctttcctgat gagctaatgg cggtatgtga tggtggccct tgctggattt
      901 gaaccagcga cctggcgatt atgagtcgct cgctctcacc actgagctaa agggccgggt
      961 caaaaaataa taatcagatg aaaatcaata atcaagccct tgcctggata catatctgtc
     1021 tggcgggaag ccataatagc ggtgaaatac agaaataaag taggaccagc ttgaataacc
     1081 gcatttttct gctacagcct gtccatatcc atgccgggaa cataacatat tcacagcaac
     1141 acgcatccgc tcttccagca acaagcgact gaacatgtgc ccttcatttt tcagttttat
     1201 ctttaacaaa ctctcactca tatgcaggcg taacgcaatc gcaccaagcg tccagcttgc
     1261 tgatatatct gtctgaatta tcgccctgac tttggcactt atactggata aacatccact
     1321 taaaaataat aatatccgtt catctgattc aaacagcgac aggcatgcca tcataagaaa
     1381 catatccgtg gtatctccgg aaaatctctg gctggtaatt aaagcctcag ccaacgcagg
     1441 gttgttgggt tccagtgaca gataaagcgg aacgtcagtc agatgagttc ttgtcagctt
     1501 atgctgaatt tccagatatt gacttactat ggaatggttt atatcgaaaa ttttaacttt
     1561 gccataatgc ataaggaaaa gcgccctgat gcatttggtg gccagaacga ctgagccggg
     1621 cttaagtgac aacgtatcct tttcaagaaa aatattaatt ggggagcaaa ccatgataac
     1681 tgaacagaca acaaccatta taattttact ttcattagca attggttagt tcaattatag
     1741 ccccaaaagg taaattatca tcaacacata agcaaaggac tgacaggtgc cgctaacacc
     1801 caccagccgc ccatttacca caaataaaaa agccttcagg actgaaggcg tctgtaacaa
     1861 ccgcactgat agtctgccag acccgccata acaagctggg tcagtattaa ctggcagcgt
     1921 tcgcgtgaaa ggtaagtatt ctgcgcaatc tccccgactg tcgccggttc ggtgacgctt
     1981 aattcatcaa acacaactct ggcggtttct gtcatatcct gctgtttcag catgtctttt
     2041 taccctttcc ggttaacgtg acacaccaat aactcttgcc gaaaaagcca gcaagctgaa
     2101 agacctgtat taataactac cagcacattt aacgcactgc gctactttgc gggcacaaaa
     2161 aacccgctca gaggcggggt caagctatgc ggcgaaataa ccactcttaa cagcatacct
     2221 gattttttac gtacgtaaat gctttgccgt gcatattttt catgcaaatg tcacgtcctg
     2281 ctatttttca gtcttataaa tttaaaacca tagaaaaaat caattatgtt ttaaaaatgg
     2341 ataggtaaag aataacaagt gacacagatt caaaccaaaa tggaaaaggg tggcaaccca
     2401 caaacgccca ctccacatcc atgacaatcc atacacaaca ccagataacg tggcaaataa
     2461 tacaagtaaa gcaccacctg aatagtgata aaaaccaaac aacaaagccg ccacaattaa
     2521 tgcaaccaat ggagacgtta cttctgatag ccgtgattga atataccctc taaataatga
     2581 ttcctctgcc agagacacaa aaaacaaatt agccaatata aactctggca accactcagg
     2641 aaaatgaatc tctggcttta atccaccaaa aaaaacagcc aaaaacagga taagaggaac
     2701 agagagcgac agagcccccc acttccacaa agacacttct gattttactt cttttttaaa
     2761 caaagaagat gtacacagga ctaacaaaaa tggcaccagc gctttatcaa aattaaaata
     2821 cattgtatag ggagtactct gagggccaac agtaacagaa tttagcacta caggattgtg
     2881 aaaccctggc catagatgga aagataatgc tatggctgat aaaactatgc caacttcata
     2941 tatagattta gcccaggcgt tatatttcca gttgaacttc aaaataataa aaaaaacgat
     3001 tgtagcaaca aaaaataaca ccgaccaatc aataatatca ttaagcacag ccaggacaac
     3061 agacaccgtc aacaatgaaa aagccactac cttatgccaa ctgagagttg acagtgacag
     3121 tactaacaca atccacataa gcactccttt tatttaatga tgaagattga ttatcaatat
     3181 tttcaattca ccaggcaaca ttttatctac cttccacaat acatgaccat caaaaaataa
     3241 acatgttaat tataaacaca gaaaacataa ccctcatcac tatatatccc taccgcatat
     3301 ccatatctaa ccggacattc agagccataa gcattccttc aataatacct tccgctttat
     3361 aaagcctttt accaataagc ccatcagaac atctatgctt acgtgcaaga gccataaatg
     3421 tcattccacc tacgtaataa tccaccaaca aatcgtgcaa atactgatta ttcttgttta
     3481 atcgtgccat acaaccacaa attatcatgg cgtcatcatc agaacactga ggacgtgatt
     3541 tcactttagt cgggattaat cctttaaaac cagcagctat cgagggccat gttacatctt
     3601 catgattatt tgctgcccat gccccccatc gctcaagaac catctggata tcacgcgcca
     3661 tcgttaccac ctctgatttc gtaaatcttc acgcccagcc gtccacctgg cacaggctga
     3721 ccgcgcacaa tattgatttc atcaaactgc tcgtcatcaa tgagcacttc cgcatgcgtc
     3781 agcgcatcca gcggtgcttt cagaatgttg tccaggtcac ggcggcgctt atccggtggt
     3841 tctgcaataa tttttattgc cagccgtccg gacaggctta atttcagccg ctgctggcga
     3901 acaataagcg ccacagcccg gcgataacgc tcaccggctt ttgatacaaa atatgtgctg
     3961 ccacgacgtc gccagtaggt gttcaccgtc ggcgggtaag gcaaaacaaa ctctatacgc
     4021 atcagtaacc tcttttaccc gagcacgccg gttgcaaaag cgtgatcaag aaaacgaaaa
     4081 attaaatcaa cctgggaacc atgcttttct tcgaacgcca gcggatccgc atgaagctcg
     4141 ttgtgatgct cccgacacag cggtagcgtg aaaatatcgt gggattttgt tcccattcc
//
LOCUS       DAZUDJ010000177         3992 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.181, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000177 DAZUDJ010000000
VERSION     DAZUDJ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3992
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.181"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..3421
                     /locus_tag="ACHY1N_005057"
     CDS             <1..3421
                     /locus_tag="ACHY1N_005057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047190.1"
                     /translation="KSTQMMSVIDAIGEGPIEGPVKGLQSILVNKTPLTDTDGNPVIH
                     GVTAVWRAGEQEQTPPEGFESSGSETALGVEVTKAKPVTRTITSANIDRLRVTFGVQS
                     LVQTTSQGDRNPASVRLLIQLQRNGNWVTEKDVTINGKTTSQFLASVILDNLPPRPFN
                     IRMVRETADSTTDQLQNRTLWSSYTEIIDVKQCYPNTAIVGLQVDAEQFGGQQMTVNY
                     HIRGRIIQVPSNYDPEKRTYSGIWDGSLKPAYSNNPAWCLWDMLTHPRYGMGKRLGAA
                     DVDKWALYAIGQYCDQTVPDGFGGTEPRMTFNAYLSQQRKAWDVLSDFCSAMRCMPVW
                     NGQTLTFVQDRPSDVVWPYTNCDVVVDDNGVGFRYSFSALKDRHTAVEVNYTDPQNGW
                     QTSTELVEDPEAILRYGRNLLKMDAFGCTSRGQAHRAGLWVIKTGLLETQTVDFTLGS
                     QGLRHTPGDIIEICDNDYAGTMTGGRILSIDAASRTLTLDREVTLPETGAATVNLING
                     SGKPVSVAITAHPAPDRIQVSTLPDGVETYGVWGLSLPSLRRRLFRCVSIRENTDGTF
                     AITAVQHVPEKEAIVDNGASFEPLSGSLNSVIPPAVQHLTVEVSAADGQYLAQAKWDT
                     PRVVKGVRFSLRLTSGKGTDARLVTTAITADTEHRFSGLPLGEYTLTVRAINSYGQQG
                     EPATTTFRIAAPAAPSRIELTPGYFQITATPHLAVYDPTVQFEFWFSEKRIADIRQVE
                     TAARYLGSALYWIAASINIKPGHDYYFYIRSVNTVGKSAFVEAVGRASDDAEGYLDFF
                     KGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITNVSNEITQTVNKKLENQSAAIQQI
                     QKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIENTPAGMQSQVLLAADRIAMIN
                     PANGNTKPMFVGQGDQIFMNEVFLKYLTAPTITSGGNPPAFSLTPDGRLTAKNADISG
                     NVNANSGTLNNVTINENCRVLGKLSANQIEGDLVKTVGKAFPRDSRAPERWPSGTITV
                     RVYDDQPFDRQIVIPAVAFSGAKHEKEHTDIYSSCRLIVRKNGAEIYNRTALDNTLIY
                     SGVIDMPAGHGHMTLEFSVSAWLVNNWYPTASISDLLVVVMKKATAGITIS"
     gene            3489..>3992
                     /locus_tag="ACHY1N_005058"
     CDS             3489..>3992
                     /locus_tag="ACHY1N_005058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044384 - host outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HFS4047191.1"
                     /translation="MRKLCAVILSAVVWQVAAATPASAAEHQSTLSAGYLHASTNVPG
                     SDDLNGINVKYRYEFMDALGLITSFSYANAEDEQKTRYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNP"
BASE COUNT          921 a         1047 c         1220 g          804 t
ORIGIN      
        1 taagtccacg cagatgatga gcgtgattga cgccattggt gaagggccga ttgaaggtcc
       61 ggtgaagggg ctgcagagta ttctggtgaa caaaacccca ctgacggaca cggacggcaa
      121 tcccgtgata cacggtgtga ccgcggtctg gcgcgccggg gagcaggagc agacaccgcc
      181 ggaaggtttt gagtcatccg gctctgaaac cgcactgggc gtggaagtga cgaaggcaaa
      241 gccggtgacg cgcaccatta cgtccgcgaa cattgaccgc ctgcgggtta ccttcggggt
      301 gcagtcactg gtgcagacca cctcacaggg tgaccgtaac ccggcatccg tccgcctgct
      361 gattcagctg cagcgtaacg gtaactgggt gacggaaaag gatgtcacca ttaacggcaa
      421 gaccacctca cagttcctcg cttcggtgat tctggataat ctgcctcccc gtccctttaa
      481 catccggatg gtccgggaga cggcggacag caccacggac cagctgcaga acagaacgct
      541 gtggtcgtca tacaccgaaa tcatcgatgt gaaacagtgc tacccgaaca cggcgattgt
      601 ggggctgcag gtggatgcgg agcagtttgg cggtcagcag atgacggtga actaccatat
      661 ccgcggtcgc atcatccagg taccgtcaaa ctatgacccg gaaaaacgca cgtacagcgg
      721 catctgggac ggcagcctga aaccggcata cagcaacaac ccggcctggt gcctgtggga
      781 catgctgact cacccgcgct acggcatggg aaaacgcctg ggggccgcgg atgttgacaa
      841 gtgggcgctg tatgccatcg ggcagtactg cgaccagacg gtcccggatg gtttcggggg
      901 cacagagccg cggatgacct ttaatgcgta cctgtcacaa cagcgtaagg cgtgggacgt
      961 tctcagtgat ttctgctcgg cgatgcgctg tatgccggta tggaacggcc agacgctgac
     1021 gttcgttcag gaccgcccgt cggatgtggt gtggccgtac accaactgcg atgtggtggt
     1081 ggatgataac ggcgtggggt ttcgctacag cttcagcgcc ctgaaggacc gccacacggc
     1141 ggtggaggtg aattacaccg acccgcagaa cggctggcag acctccacgg aactggtgga
     1201 agacccggaa gccatactgc gctacgggcg caacctgctg aagatggatg cgttcggctg
     1261 taccagtcgc ggtcaggccc accgtgccgg gctgtgggtg ataaagaccg gactgctgga
     1321 aacgcagacg gtggatttca cgctcgggtc acaggggctg cgtcacacac ccggtgacat
     1381 tattgaaatc tgtgataacg actatgccgg gaccatgacc ggcggacgta tcctgtccat
     1441 cgatgccgcc agccgcaccc tgacactgga ccgtgaggtg accctgccgg agaccggtgc
     1501 cgccacggtg aacctgatta acggcagcgg taagccggtg agcgtggcca tcactgcaca
     1561 ccccgcgccg gaccggatac aggtcagcac cctgccggat ggcgtggaga catacggtgt
     1621 gtggggactc tccctgccgt cactgcgtcg tcgcctgttc cgctgtgtct ccatccggga
     1681 aaacacggac ggcacctttg ccatcacggc ggtgcagcac gtaccggaaa aagaagccat
     1741 tgtggataac ggggccagct ttgagccact gtccggttcg ctgaacagcg tcatcccgcc
     1801 ggctgtgcag cacctgacgg tggaggtgag cgcggctgac ggtcagtatc tggcacaggc
     1861 gaaatgggac acgccgcggg tggtgaaggg cgtgcgcttc agtctgcgcc tgaccagtgg
     1921 taagggaacg gatgccagac tggtgaccac cgccatcacc gcagacacgg agcaccgttt
     1981 cagcggcctg ccgctcgggg aatacaccct gacggtgcgg gcgataaaca gctatggcca
     2041 gcagggtgaa cctgccacca ccaccttccg gattgccgca ccggcagcac cgtcgcggat
     2101 tgagctgacg ccgggctatt ttcagataac cgccacgccg catcttgccg tttatgaccc
     2161 gacggtacag tttgagttct ggttctcgga aaagcggatt gcggatatca ggcaggttga
     2221 aaccgcagcc cgctatcttg gctcggcgct gtactggata gctgccagta tcaatatcaa
     2281 accgggccat gattattatt tttatatccg cagtgtgaat actgttggca aatcggcatt
     2341 cgtggaggct gtcggtcggg cgagcgatga tgcggaaggt tacctggatt ttttcaaagg
     2401 agaaatcggg aaaacacatc tggcccagga gctgtggacg cagattgata acggtcagct
     2461 tgcgccggac ctggctgaaa tcaggacgtc cattacgaat gtcagcaatg aaatcacgca
     2521 gaccgtcaat aaaaaactgg aaaatcagag tgcggcaatc cagcagatac agaaagttca
     2581 ggttgataca aataataacc tgaacagcat gtgggccgtg aaactgcagc agatgcagga
     2641 cggacgcctt tatattgcgg gtatcggtgc cggtattgag aatacgccag caggaatgca
     2701 gagtcaggtg ctgctggcgg cagacaggat tgcgatgatt aatcctgcga atggcaacac
     2761 aaagccgatg tttgttggtc agggcgatca gatatttatg aatgaagtgt tcctgaaata
     2821 tctgacggct cccaccatta ccagcggcgg taatcctccg gcattttccc tgacaccgga
     2881 cgggcggctg acggcgaaaa atgccgatat cagcggtaac gtgaatgcga actccgggac
     2941 gctcaacaac gtcacgatta acgagaactg tcgggttctg ggaaaattgt ccgcgaacca
     3001 gattgaaggc gatctcgtta aaacagtggg caaagctttc ccccgggact cccgtgcacc
     3061 ggagcggtgg ccatcaggaa ccattaccgt cagggtttat gacgatcagc cgtttgaccg
     3121 gcagattgtt attccggcgg tggcattcag cggcgctaaa catgagaaag agcatactga
     3181 tatttactcc tcatgccgtc tgatagtgcg gaaaaacggt gctgaaattt ataaccgtac
     3241 cgcgctggat aatacgctga tttacagtgg tgttattgat atgcctgccg gtcacggtca
     3301 catgacactg gagttttcgg tgtcagcatg gctggtaaat aactggtatc ccacagcaag
     3361 tatcagcgat ttgctggttg tggtgatgaa gaaagccact gcaggcatca cgattagctg
     3421 aattttataa cccagatacg ggcgccagaa atggcgcctt ttttattgca gaaaagcgag
     3481 aggtaattat gcgtaaatta tgtgctgtta ttttgtccgc agtagtctgg caggtcgccg
     3541 ctgctacgcc agcgagtgca gcagaacatc agtccacgct gagcgcgggg tatctccatg
     3601 cctcgacgaa cgttcccggt agtgatgatc tgaacgggat taacgtgaaa taccgttatg
     3661 agtttatgga cgcgctgggg ctgattacgt ccttcagtta tgccaatgct gaggatgagc
     3721 aaaaaacgcg ctacagcgat acccgctggc atgaagattc cgtgcgtaac cgctggttca
     3781 gcgtgatggc ggggccgtct gtacgcgtga atgaatggtt cagcgcgtat gcgatggcgg
     3841 gtgtggctta cagccgtgtg tcgactttct ccggggatta tctccgcgta actgacaaca
     3901 aggggaaaac gcacgatgtg ctgaccggaa gtgatgacgg tcgccacagc aacacgtctc
     3961 tggcgtgggg agctggcgtg cagtttaacc cg
//
LOCUS       DAZUDJ010000178         3988 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.182, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000178 DAZUDJ010000000
VERSION     DAZUDJ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3988
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.182"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            81..485
                     /locus_tag="ACHY1N_005059"
     CDS             81..485
                     /locus_tag="ACHY1N_005059"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4047192.1"
                     /translation="MKSLTAVRKKSPNYPVEFKIKMVELSHRPEISVAQLAREHGIND
                     NLLFKWRQYWREGKLRPPSTTENNVPELLPITLDAEDVVPTTSPRSQPVAAATPESLN
                     ISCEVTFRHGSLRLNGAISENILNLLIRELKR"
     gene            482..829
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005060"
     CDS             482..829
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004966400.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFS4047193.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTTLKDDPMSGHVF
                     IFRGRNGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     gene            878..2416
                     /locus_tag="ACHY1N_005061"
     CDS             878..2416
                     /locus_tag="ACHY1N_005061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc22 family transposase"
                     /protein_id="HFS4047194.1"
                     /translation="MSSSLPDDINALKRLLAEQEALNRALLEKLNEREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLKALQKESDTLTGRVDDPAVQRPLRQTRTRKPF
                     PESLPRDEKRLLPAASCCPECGGSLSYLGEDAAEQLELMRSAFRVIRTVREKHACTQC
                     DAIVQAPAPSRPIERGIAGPGLLARVLISKYAEHTPLYRQSEMYGRQGVELSRSLLSG
                     WVDACCRLLSPLEEALQDYVLTDGKLHADDTPVPVLLPGNKKTKTGRLWTYVRDDRNA
                     GSTLAPAVLFAYSPDRKGIHPQTHLAGFSGVLQADAYAGFNELYRDGRITEAACWAHA
                     RRKIHDVHVRTPSALTEEALKRIGELYAIEAEIRGMTAEQRLAERQLKTKPLLKSLES
                     WLREKMKTLSRHSELAKAFAYALNQWPALTYYADDGWAEADNNIAENALRMVSLGRKN
                     YLFFGSDHGGERGALLYSLIGTCKLNGVEPESYLRYVLDVIADWPINRVGELLPWRVA
                     LPTE"
     gene            complement(2455..2577)
                     /locus_tag="ACHY1N_005062"
                     /pseudo
     CDS             complement(2455..2577)
                     /locus_tag="ACHY1N_005062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310013.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
     gene            complement(2588..3286)
                     /locus_tag="ACHY1N_005063"
     CDS             complement(2588..3286)
                     /locus_tag="ACHY1N_005063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030430 - host cell cytoplasm [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HFS4047195.1"
                     /translation="MQHIHGESLNESVKSEQSPRVVLWEIDLKAQGGERYFFCNELNE
                     KGEPVTWQGRKYQAYPIDGSGFEMNGKGSSARPSLTVSNLFGLVTGMAEDLQSLVGAT
                     VVRRRVYARFLDAVNFVAGNPEADPEQELSDRWVVEQMSELTAMTASFVLATPTETDG
                     ALFPGRIMLANTCMWDYRSDECGYNGPAVADEFDNPTTDIRKDRCSKCMRGCELRRNV
                     GNFGGFLSINKLSQ"
     gene            complement(3286..3627)
                     /locus_tag="ACHY1N_005064"
     CDS             complement(3286..3627)
                     /locus_tag="ACHY1N_005064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047196.1"
                     /translation="MAEIKTLHLVPREGMQVSEKPSVARVRFGDGYEQRRPTGLNPQL
                     KTFQAVFRVTDESTRRWLDEFLSWHGGYRAFLWRPPKHNRTVRVVCREWSVTDNVRYS
                     DFSCTIEQVVN"
     gene            complement(3620..>3988)
                     /locus_tag="ACHY1N_005065"
     CDS             complement(3620..>3988)
                     /locus_tag="ACHY1N_005065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4047197.1"
                     /translation="AVANAKGGVYTSANLSAYSNSIVDTPTYFAFAKGAGLMGEAGPE
                     AIMPLTRAADGSLGVRAVGSMNGSAGLVYSPVYHIAIQNDGTNGQIGPEAAGSLVQLI
                     DQRVQAVMLSMRRDGGMLSG"
BASE COUNT          898 a         1242 c         1056 g          792 t
ORIGIN      
        1 taagcgtcgt ctcagcaccg tctggcagat cctgaaattc ctgagagaat agtggacacc
       61 aaatatggtg gacgctatcc atgaaatcat taaccgcagt gcgtaaaaaa agccctaatt
      121 atcccgttga gttcaaaatc aaaatggttg aactctcgca tcgaccagag atctccgtag
      181 cgcaactcgc tcgtgagcat gggatcaacg ataatttgct gttcaagtgg cgccagtact
      241 ggcgcgaagg aaaactacgt cctccttcaa caacagaaaa caacgtgcct gagctgctcc
      301 cgataacact tgatgccgaa gatgttgtcc ctacaacctc cccccggtca caacctgtag
      361 ctgctgcgac acctgaatca ctcaatatca gctgtgaagt gacgttccgg cacggatcac
      421 tccgtctgaa tggtgccatc agcgaaaata tcctgaacct gctgatacgg gagctcaaac
      481 gttgatccca ttaccatcag ggacaaagat ctggctggtc gctggcatca ccgatatgag
      541 aaacggcttc aacggcctgg cggcaaaggt gcagacgacg ctgaaagacg atccgatgtc
      601 aggtcacgtt tttatcttcc gtgggcgtaa tggcagtcag gtaaagctcc tctggtctac
      661 cggcgatgga ctgtgtctgc tgaccaaacg gctggagcgc ggccgcttcg cctggccgtc
      721 agcccgggat ggcaaagtgt tcctcacacc ggcacagctg gcgatgctgc tggaaggtat
      781 cgactggcgg cagcctaaaa gactgcttac gtccctgact atgttgtaag cctctttatc
      841 ctggtcgacg ctgaatgagc ctggtaatat acccggtatg agcagctcac ttcctgacga
      901 tatcaatgca ctgaaacgtc tccttgccga acaggaggcg ctgaaccgtg ccctgctgga
      961 aaagctgaac gagcgtgaac gcgaaataga ccatctgcag gcacagctgg ataagctgcg
     1021 ccggatgaac ttcggcagcc gctccgaaaa agtctcccgt cgtatcgcac agatggaagc
     1081 tgacctgaag gcacttcaga aagaaagtga tacccttacc ggtcgggttg acgacccggc
     1141 cgtgcagcgc ccgctgcgtc aaacccgcac ccgcaaaccg ttccccgaat cactcccccg
     1201 cgatgaaaaa cggctgctgc cggcagcatc atgctgcccg gaatgtggag gctcactgag
     1261 ctatctgggt gaggatgccg ccgaacagct ggagttgatg cgcagcgcct tccgggttat
     1321 ccggactgta cgtgaaaagc atgcctgtac tcagtgcgat gccatcgtgc aggcccccgc
     1381 gccttcacgg cccatcgagc ggggtatcgc aggaccgggg ctgctggccc gcgtgctgat
     1441 ctcaaagtat gcagagcaca ccccgctgta ccgccagtct gaaatgtacg gccgccaggg
     1501 cgtggagctg agtcgttcac tgctgtcggg ctgggtggat gcatgctgcc ggctactgtc
     1561 accgctggaa gaagcgcttc aggactatgt gctgactgac ggtaagctcc atgctgatga
     1621 cacgcctgtc ccggtgctgt tgccaggcaa taagaaaacg aagaccgggc ggttatggac
     1681 ctacgttcgt gacgaccgta acgccgggtc aacgctggcg ccggcggtgt tgttcgctta
     1741 cagcccggac agaaaaggca tccatccgca gacccatctt gcggggttca gtggtgtact
     1801 gcaggcggat gcatacgccg ggttcaacga gctgtaccgg gatggccgga taacggaagc
     1861 cgcctgttgg gctcacgccc gccgtaaaat ccacgatgtg cacgttcgca ccccgtcagc
     1921 cctgacggag gaagcgctga aacggatcgg cgaactgtac gccatcgagg cagagataag
     1981 gggaatgacg gcggagcagc gccttgccga acgtcagttg aaaacgaaac cgctgctgaa
     2041 atccctggaa agctggctgc gtgaaaagat gaaaaccctg tcgcgacact cagaactggc
     2101 gaaagcgttc gcatacgccc tgaaccagtg gccggcgctg acgtactatg cagatgatgg
     2161 ctgggctgag gcggacaata acatcgctga aaatgcgttg cggatggtca gtctgggccg
     2221 caaaaactac ctgttcttcg gttcggatca tggaggagag cggggagcgc tgctgtacag
     2281 cctgatcggg acgtgcaaac tgaacggagt ggagccagaa agctacctcc gctatgtcct
     2341 tgacgtcata gccgactggc cgataaaccg ggtcggcgaa ctgctcccct ggcgcgtagc
     2401 actgccgact gaataacaca tccccgtcaa tacggttctt gctgcacgct tacctgcaga
     2461 gatattcaca caagggatat accgctcccc ctccggcgtt ctcaccacga agccgcacga
     2521 ctccgcaggc gcacaccgcc gggcatgcgc cagaatcgct gattcagtct gtgtcataaa
     2581 ccgggattta ctgcgaaagt ttattaatgg aaaggaaacc gccaaagttg ccgacattcc
     2641 tgcgcagttc acacccgcgc atgcatttac tgcatctgtc cttccggata tccgtggtgg
     2701 ggttgtcgaa ctcatccgcc actgccggac cgttataccc gcattcatca gagcggtaat
     2761 cccacataca ggtgttcgcc agcatgatgc gaccgggaaa cagcgccccg tccgtctcgg
     2821 tcggtgttgc cagcacaaac gaggctgtca tggccgtcag ctctgacatc tgctccacca
     2881 cccagcggtc gctcagctcc tgctccgggt ccgcttccgg attgcccgcc acaaaattca
     2941 ccgcatccag aaaacgggca tacacccggc ggcggaccac cgtggccccc accaggctct
     3001 gcaggtcctc cgccatcccg gtgaccagac caaacagatt cgacaccgtc agcgacgggc
     3061 gggcactgct gcccttcccg ttcatctcaa agccactgcc gtcaatcggg tatgcctggt
     3121 acttccgccc ctgccaggtc accggctccc ctttttcatt cagctcatta cagaaaaaat
     3181 accgctcacc accctgggcc ttcaggtcaa tttcccagag caccacccgc ggtgactgct
     3241 ctgatttaac cgactcgttc aggctttccc cgtgaatatg ctgcatcagt tcaccacctg
     3301 ctcaatcgta cagctgaaat cactgtaccg gacgttatcc gtgacgctcc actcccggca
     3361 caccaccctc accgtccggt tatgtttcgg cggtcgccac aaaaaggcac ggtaaccacc
     3421 atgccaggat aaaaattcat ccagccagcg ccgggttgac tcatccgtca cccggaacac
     3481 cgcctgaaac gtcttcagtt gaggattcag tcctgtgggg cgacgctgtt cataaccgtc
     3541 accaaaccgt accctcgcca ccgacggttt ctcactcacc tgcatccctt cacgcgggac
     3601 cagatgcagc gtttttatct cagccactca gcattcctcc gtcacgtcgc atggacaaca
     3661 tcaccgcctg cacccgctgg tcaatcagct gcacaagact gcctgccgcc tccggcccta
     3721 tctggccatt agtcccgtca ttctgaatgg cgatatggta gaccggggaa tacaccaggc
     3781 ccgcactacc gttcatactg cccaccgctc gcacacccag cgagccatcc gccgcccggg
     3841 tcaggggcat aatggcttca ggaccggcct cccccatcag tcccgcccct tttgcaaagg
     3901 caaagtacgt gggcgtatcc acaatactgt tgctgtacgc actcaggttt gccgaggtat
     3961 acacgccgcc ttttgcattg gccaccgc
//
LOCUS       DAZUDJ010000179         3917 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.183, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000179 DAZUDJ010000000
VERSION     DAZUDJ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3917
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.183"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            30..656
                     /locus_tag="ACHY1N_005066"
     CDS             30..656
                     /locus_tag="ACHY1N_005066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047198.1"
                     /translation="MKKIIYTFSLVVALLLALRCAAYIDFSEKDMLKSIIPAWIQAIG
                     SILAIIIAGMISANQIKHEKQLEKRKVAESDLAKMHIVRALIIRSLTLMNEVRQAIER
                     GEESDFQQVSPWTMRNTKRAIDNLNLFEIPEGMLALDLLAIGPSLEEIATLWERCMEE
                     SLHTENNKPTIDSYNELDQGSQEVLKICEAAFKLATQEVNRLAAIVKE"
     gene            1113..1538
                     /locus_tag="ACHY1N_005067"
     CDS             1113..1538
                     /locus_tag="ACHY1N_005067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4047199.1"
                     /translation="MELQDWRKEPRKNYSNEFKLRMVELASQPGACVAQIARENGVND
                     NVIFKWLRLWQNEGRVSRRLPVTTSSDTGVELLPVEITPDEQKEPVAAIATSLSTSTQ
                     TRVSASSCKVEFRHGNMTLENPSPELLTVLIRELTGRGR"
     gene            1535..1885
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005068"
     CDS             1535..1885
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311895.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFS4047200.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQVQHVLNDNPFSGHLF
                     IFRGRRGDTVKILWADADGLCLFTKRLEEGQFIWPAVRDGKVSITRSQLAMLLDKLDW
                     RQPKTSRRNSLTML"
     gene            1916..3220
                     /locus_tag="ACHY1N_005069"
     CDS             1916..3220
                     /locus_tag="ACHY1N_005069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFS4047201.1"
                     /translation="MSQKYLIRIAELERLLSEQAEALRQKDQQLSLVEETEAFLRSAL
                     TRAEEKIEEDEREIEHLRAQIEKLRRMLFGTRSEKLRREVELAEALLKQREQDSDRYS
                     GREDDPQVPRQLRQSRHRRPLPAHLPREIHRLEPEESCCPECGGELDYLGEVSAEQLE
                     LVSSALKVIRTERVKKACTKCDCIVEAPAPSRPIERGIAGPGLLARVLTGKYCEHLPL
                     YRQSEIFARQGIELSRALLSNWVDACCQLMTPLNDTLYRYVMNTRKVHTDDTPVKVLA
                     PGRKKAKTGRIWTYVRDDRNAGSSEPPAVWFAYSPDRQGKHPVQHLRPFRGILQADAF
                     SGYDRLFSAEREGGALTEVACWAHARRGFADLYKISKDPRAAIAVKKIAGLYRLEKKI
                     SSRPVEKIRQWRQRYARPILEDLWSWLEEQEPQCSPGSKRTA"
     gene            3296..3676
                     /locus_tag="ACHY1N_005070"
     CDS             3296..3676
                     /locus_tag="ACHY1N_005070"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4047202.1"
                     /translation="MQKNVTPGRRKGCPNYPPEFKQQLVAASCEPGISISKLALENGI
                     NANLLFKWRQQWREGKLLLPSSESPQLLPVTLDAAAEQPESLAEDPETLSISCEVTFR
                     HGTLRFNGNVSEKLLTLLIQELKR"
     gene            3673..>3917
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005071"
     CDS             3673..>3917
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536669.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFS4047203.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVF
                     IFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPSAR"
BASE COUNT         1046 a          925 c         1004 g          942 t
ORIGIN      
        1 tgtgaagaag tatagaggga ttaatcatca tgaaaaaaat aatatatact ttttctttgg
       61 ttgtggcttt attattggcg ttaagatgtg ccgcctatat tgatttttct gaaaaagaca
      121 tgctcaagtc aatcattcct gcttggattc aagccattgg tagcatttta gcaattatta
      181 ttgccggtat gatctcggcc aatcaaatta aacatgagaa acagcttgaa aagagaaagg
      241 tagcagagtc agatttggct aaaatgcata tagtaagagc gctgataata cgttcgttaa
      301 ctttaatgaa tgaggttcgt caggcaattg agcgtggcga agaaagcgac tttcagcaag
      361 tgtctccttg gactatgcgt aatacaaaac gtgcaattga taatttaaat ttatttgaaa
      421 taccagaggg gatgttagct ctcgatctgt tggctatagg tccatctctc gaggaaatag
      481 caaccttatg ggagcggtgt atggaggagt cactacatac tgaaaataac aagccaacta
      541 ttgattctta caatgagctt gatcaaggct ctcaagaggt tttgaaaata tgtgaagccg
      601 cttttaaatt ggctacacaa gaggttaatc ggcttgcagc tatcgttaaa gagtaacttt
      661 cacataggaa tttattttat atgtgctctt agagtacatt acttttagta atttgtactc
      721 tttggttgta tatgccgaca acgatatagg ttttaaagta ttactgtgaa tttatggggt
      781 aacatcatta taagccgatt aatcctccta gattacttac ctatccttga agaactgtcc
      841 tacagcccgc ttcgtgtcat aagcgggctg taggcataga ataactaatc aatcattaga
      901 gtgagactat tttcagcttt ggtgaggtgg gatgatgatt gctttagagt ttaataggac
      961 actccggtcg ctcccttcgt atctggatgt aaagccccct attttttctc caaaacctta
     1021 ccttatcgta agcgtaaact gaccgccgta tgtagccatc agacgagaat tggtaactta
     1081 gacgcccatc tgatatagac ggacatctaa gtatggaatt acaggactgg cgaaaagaac
     1141 ctcgtaaaaa ctattcgaat gaattcaaac ttcgtatggt ggaactggca tcacaacctg
     1201 gagcttgtgt tgcacagatt gcacgtgaaa atggcgtcaa tgataatgtt attttcaaat
     1261 ggctcaggct ctggcagaac gaagggcgtg tttcgcggcg tcttccggta acgacctctt
     1321 ctgacactgg cgttgaatta ttacctgtag aaataacgcc ggatgagcag aaagaacctg
     1381 tggcggccat tgcgacgtct ttatccactt ccactcagac cagagtcagt gccagttcct
     1441 gcaaggtgga attccgtcac ggtaacatga cgctggaaaa tccatcgcca gagctgctca
     1501 cggtgttgat ccgtgaactg accgggaggg gaagatgatc tcactcccat caggtacccg
     1561 tatctggctc gttgccggcg ttaccgatat gcgtaaatcc ttcaacggac tgggagaaca
     1621 ggtacaacat gtgctgaatg ataatccctt ctccggtcac ctgtttatct tccgtggccg
     1681 acggggtgac accgttaaaa ttctttgggc tgatgctgat ggtctgtgcc tgttcaccaa
     1741 acgcctggag gaaggccagt ttatctggcc tgcggtacgt gacggcaagg tatccattac
     1801 ccgctcgcaa ctggcaatgc tcctcgataa gctggactgg cgtcagccaa aaacatcccg
     1861 ccgtaactca ctgacaatgt tgtaaaaaac tcctgaccgc attataaaaa cggtcatgag
     1921 tcagaaatac ctcattcgca tcgcagagct ggaaaggttg ctctctgagc aggctgaagc
     1981 cctccgtcag aaagaccagc aactgagtct ggttgaagag acggaagcct tcctgcgctc
     2041 tgcactgaca cgtgccgaag aaaagatcga agaagatgaa cgggaaatag aacatctgcg
     2101 ggctcagata gaaaaactgc gccggatgct gttcggtacc cgttctgaaa aactgcgtcg
     2161 tgaagttgaa ctggctgagg ccctgctgaa acaacgtgaa caggacagcg atcgttacag
     2221 tgggcgggaa gacgatcctc aggttccccg ccagttgcga cagtcgcgcc atcgtcgtcc
     2281 gttaccggca caccttcccc gtgaaataca ccgcctggag ccagaagaaa gctgttgccc
     2341 ggagtgtggc ggtgagctgg attatctggg ggaagtcagc gctgaacagc tggaactggt
     2401 gagcagtgcc ctgaaagtga tccgcacaga acgggtaaaa aaagcctgta caaaatgtga
     2461 ctgtattgtt gaagcaccgg cgccgtcccg cccgatagag cgtggtatcg cgggccccgg
     2521 attacttgcc cgcgtgttaa cgggaaaata ctgcgaacat ctgccactgt atcgtcagag
     2581 tgaaatcttt gcccgccagg gcatcgaact gagccgggca ttactctcca actgggttga
     2641 cgcatgttgt cagttaatga ctccgctgaa tgataccctg taccgttacg tgatgaacac
     2701 ccgcaaggtt cacactgacg acacaccagt aaaagtgctg gcaccgggca gaaaaaaggc
     2761 aaaaacagga cgcatctgga cgtatgtccg ggatgaccgg aatgcgggct catcagagcc
     2821 accggcggtc tggttcgcct actcaccaga caggcaggga aaacatccgg tacaacacct
     2881 tcgtcccttc cggggtatcc tgcaggcgga tgcgttcagc ggttacgatc ggctgttcag
     2941 tgccgaacgt gaaggtggtg cactgacaga agttgcgtgc tgggcccatg cccgcagggg
     3001 cttcgccgac ctgtataaaa tcagtaaaga tccacgggct gccatagccg tgaagaaaat
     3061 cgcggggttg taccgtcttg agaagaagat cagtagccgc cccgtggaaa aaatccgcca
     3121 gtggcgacag cgttatgccc gtccgatact ggaagatctg tggtcatggc ttgaagagca
     3181 ggaaccgcaa tgttctccgg gaagtaagcg tacagcctga accgtctggt cagaatctga
     3241 cgaattagac aaagtggtgt ccaccaaata agtagtggga accaaagtgt cagatatgca
     3301 gaaaaatgtg actcccggca ggcgaaaagg ctgccctaat tatcctcccg aatttaaaca
     3361 gcagctcgtt gctgcctcct gtgaacccgg gatatccatc tcaaaacttg ctcttgaaaa
     3421 tggcattaac gccaatctgt tgttcaaatg gcgacaacaa tggcgcgagg gaaagctgct
     3481 attaccttct tcagagagcc cccagctact tcctgtgact ctcgatgcag ctgccgaaca
     3541 gccagaatcg ctcgcagagg acccggaaac cctcagtatc agctgtgagg taacgttccg
     3601 gcacgggacg ctccgcttca atggcaatgt cagcgaaaag ctcctgactc tgctgataca
     3661 ggaactgaag cgatgatccc gttaccttcc gggaccaaaa tttggctggt tgccggtatc
     3721 accgatatga gaaatggctt caacggcctg gctgcgaaag tacagacggc gctgaaagac
     3781 gatcccatgt ccggccatgt tttcattttc cggggccgca gcggcagtca ggttaaactg
     3841 ctgtggtcca ccggtgacgg gctgtgcctc ctgaccaaac ggctggagcg tgggcgcttc
     3901 gcctggccgt cagcccg
//
LOCUS       DAZUDJ010000180         3830 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.184, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000180 DAZUDJ010000000
VERSION     DAZUDJ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3830
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.184"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..528
                     /locus_tag="ACHY1N_005072"
     CDS             <1..528
                     /locus_tag="ACHY1N_005072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P2 family phage major capsid protein"
                     /protein_id="HFS4047204.1"
                     /translation="WLEHIRTDASERVMNDVTLTSRNMDNTVAHAGKYANADALVQDA
                     RSSLLDEWHKEADDLVVIMGRNLFNSLRLPVLNSISGQNPNAELLAGQLILSSRTIGG
                     LGVFLAPFFPDATMLITSFNNLSIYWQKGSMRRLMKDEPEYNRIATYQSINDAYVVED
                     YGKCAMVTGLKFADS"
     gene            574..1374
                     /gene="gpM"
                     /locus_tag="ACHY1N_005073"
     CDS             574..1374
                     /gene="gpM"
                     /locus_tag="ACHY1N_005073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFS4047205.1"
                     /translation="MITPAQQHWQNVMAQRAGRANEGVDHAARTAHEEVLYRLRLAQA
                     RLKGVQARSAKAAIKKELLPDFSGWIEGTLEADGGQQDEVIATLMVWAIDCGDLPLAL
                     RIGAYVVRHNLIMPDNFGRTAATVLTEEICNPVLTQAGTDADADLSTFIEPLDTLWEI
                     VANQDMPDEVRAKLCKACAFARRGLSDADSMASSLKLLREAMHLNPNAGVKREIATLS
                     RALKKADSAAAPEDASTPQTQDESSKSKKTTRKPATRKTTATQKAKRG"
     gene            1476..1970
                     /locus_tag="ACHY1N_005074"
     CDS             1476..1970
                     /locus_tag="ACHY1N_005074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HFS4047206.1"
                     /translation="MSMVARTNPGPAEDDITDTDDGDTRISAGAFWPDIVLRELRLAI
                     RLPGRVTTSRLLHTATGAVAHVTRELEAWQQEQQAAGHQTLADVPAPVINGESVNLWH
                     WRNAVYTATRALILERYRDADTTDKGDRRADALDIQTSDLWRDVSWAISDILRRPRIF
                     AELC"
     gene            1970..2170
                     /locus_tag="ACHY1N_005075"
     CDS             1970..2170
                     /locus_tag="ACHY1N_005075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HFS4047207.1"
                     /translation="MKVKALEGDTVDSLCFRYYGTTQGVTEKVLDANPGLCQQVFLDA
                     GQEVEMPEPEKKKREMIQLWGE"
     gene            2173..2496
                     /locus_tag="ACHY1N_005076"
     CDS             2173..2496
                     /locus_tag="ACHY1N_005076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFS4047208.1"
                     /translation="MSTIQTGITEQVIAWLFDHLPTVYAVGAAVSISALMSLYDGRTL
                     VQTVTGSLACGVLAMAVAGSLRFFGFPEDAVTFIGASIGFMGAEKARDKVIAAFNRRV
                     KEKDE"
     gene            2493..2885
                     /locus_tag="ACHY1N_005077"
     CDS             2493..2885
                     /locus_tag="ACHY1N_005077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFS4047209.1"
                     /translation="MSNTFKFSSRSEKNLQGVNPDLVKVTRRALEISEVDFGITEGVR
                     SRYRQKQLVATGKSQTMNSRHLTGHAVDVVAYVGSQVSWEWPQYEKIAAAFRQASREL
                     NIPVEWGGDWKTLKDGPHFQLPHGAYPA"
     gene            2882..3289
                     /locus_tag="ACHY1N_005078"
     CDS             2882..3289
                     /locus_tag="ACHY1N_005078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2570 domain-containing protein"
                     /protein_id="HFS4047210.1"
                     /translation="MKLWPTLGVAFLLIAAWGTSMRLSWSLGRENARNEAQASALKST
                     ADTLNIISAGVQDMQQVLAQLRAENQQRNQDGEARREQLRNDIAKDECAHALPDARFT
                     DRLRRHAERATASAVSPAYTADADHTGNASPLP"
     gene            3427..>3830
                     /locus_tag="ACHY1N_005079"
     CDS             3427..>3830
                     /locus_tag="ACHY1N_005079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047211.1"
                     /translation="MLKTDSLREAMTRSCRWCQANPEKFTIFVESGNIETTGETPSFV
                     YRYQMVMFVMDYAGELDDLTLPLLAWLSENQPQLLLNPERNQDIKFSAVINDDDSADL
                     LFTLPLRERVRITRNSQGTPQAEHLPEPKPRLP"
BASE COUNT          901 a         1070 c         1138 g          721 t
ORIGIN      
        1 tggctggagc acatcagaac cgacgccagc gaacgcgtta tgaatgacgt gacgctgacc
       61 tcccgcaaca tggacaacac cgtggcgcac gcgggtaagt atgcgaacgc tgatgcactg
      121 gtacaggacg cgcgttcatc cctgctggat gaatggcaca aggaagctga cgaccttgtg
      181 gtgattatgg ggcgcaacct gtttaactcg ctgcgtctgc ccgtgctgaa cagcatcagc
      241 ggccagaatc caaatgcgga attacttgcc gggcagctca tcctgtcatc gcgcaccatt
      301 ggcgggctgg gcgtgttcct tgcgccgttc ttcccggatg caacgatgct gatcacctcg
      361 ttcaacaacc tgtcgattta ctggcagaaa ggttcaatgc gtcgtctgat gaaagacgaa
      421 ccggaataca accgcatcgc cacctaccag tccatcaatg acgcttatgt cgttgaagac
      481 tatggcaagt gcgcgatggt cactggcctg aagttcgccg acagctaatc aactcacggc
      541 gggcatcatg cccgcctgta acggagagaa aaaatgatta ctcctgcaca gcaacactgg
      601 cagaacgtga tggcacagcg cgcaggccgg gcgaatgaag gcgtggacca cgccgcgcgt
      661 accgcgcatg aagaggtgct gtatcgtctg cgtctggcac aggcccggct taagggcgta
      721 caggccagaa gcgcgaaagc cgccatcaaa aaagagttgt tgccggactt ttccggctgg
      781 attgagggaa cgctggaggc tgacggcggg cagcaggatg aagtgattgc cacgctgatg
      841 gtgtgggcga ttgactgcgg cgatcttccg cttgcgctgc gtattggtgc gtatgtggtc
      901 cgtcacaacc tcatcatgcc ggataacttt ggccgtactg ctgccacggt actgaccgaa
      961 gaaatctgta acccggtatt gacgcaggcc gggacggatg ccgacgcgga tttgtccacc
     1021 tttatcgaac cactggacac actttgggaa attgtcgcca accaggatat gccggacgaa
     1081 gtgcgcgcca aattatgcaa ggcgtgcgcc tttgcccgcc gtggcctgag cgatgcggac
     1141 agcatggcct catcactgaa gctgctgcgc gaagcgatgc acctgaaccc gaacgcaggt
     1201 gtgaaacgcg agattgcaac cctttcccgc gccctgaaaa aagctgattc cgcagccgca
     1261 ccagaagatg ccagcacacc gcagacgcag gacgaaagca gcaaaagtaa aaagacaacg
     1321 cggaagcctg caacacgaaa aaccaccgcg acgcagaagg cgaagcgcgg ttaacgactg
     1381 accccgtcag cgggcggcgt gcgcggtgtt ccggtttgac tccgtgaccg tttacaccgc
     1441 gcacccaccg cccgattttt tcaggagtga accccatgag tatggttgcc agaaccaacc
     1501 ccggacccgc agaggacgac atcaccgata ccgatgatgg tgatacccgt atttcagcgg
     1561 gtgcattctg gccggatatt gtgctgcgtg agctgcgtct ggcgatacga ctgccgggcc
     1621 gcgtgaccac ctcccgcctg ctgcataccg ccaccggggc cgtggcacac gttacccgcg
     1681 agctggaagc gtggcagcag gaacagcagg cggctggcca tcagacgctg gccgatgttc
     1741 cggcccccgt aattaacgga gaaagcgtca atctctggca ctggcgcaat gctgtttata
     1801 ccgccacacg cgccctgatt ctggagcgtt accgcgatgc ggacacaacg gataagggcg
     1861 accgccgggc ggacgcactg gatatacaga catcggattt gtggcgcgat gtgagctggg
     1921 ccatctctga cattctgcgc cgcccgcgaa tctttgcgga gctgtgctga tgaaagtgaa
     1981 ggcactggaa ggcgacaccg tggattcgct ctgtttccgg tactacggca cgacgcaggg
     2041 cgtcaccgaa aaggtgctgg atgccaaccc cggactctgt cagcaggtat ttctggacgc
     2101 cgggcaggaa gtggagatgc cggagccgga gaagaagaaa cgagaaatga ttcagttgtg
     2161 gggggagtag cagtgagcac cattcaaaca gggatcacag agcaggttat tgcgtggctc
     2221 tttgaccacc tgccaacggt gtatgcagta ggcgcggcag tcagcatttc cgcgctgatg
     2281 agtctttatg acggacgaac actggttcag accgtaacgg gatcgctggc gtgcggcgtt
     2341 cttgccatgg ccgtggccgg gtcgttgcgc ttcttcgggt ttcctgaaga tgccgtgacg
     2401 tttatcggcg catcaatcgg ttttatgggc gcagagaaag cacgcgacaa ggttattgcg
     2461 gcctttaatc gcagggtgaa ggagaaggac gaatgagcaa cacatttaaa ttcagcagcc
     2521 ggagcgaaaa gaatttgcag ggtgtaaatc ctgatctggt gaaagtgacc cgacgggcac
     2581 tggaaatctc ggaagtggat tttggtatca ccgaaggggt gcgcagccgt taccgccaga
     2641 agcaacttgt ggccacgggt aagagccaga ccatgaacag ccgccacctt acggggcatg
     2701 ccgtggatgt tgtggcttat gtcggcagcc aggtgtcatg ggaatggccg cagtacgaaa
     2761 aaatcgcagc agcattcaga caggccagcc gggaactgaa tattccggtg gaatggggcg
     2821 gagactggaa gaccctgaaa gacggaccgc attttcagtt accacacgga gcctatccgg
     2881 catgaagctc tggcccacgc tgggtgtcgc tttccttctg attgccgcat ggggaacatc
     2941 catgcgtctg tcgtggtcgc tgggtcggga gaacgccaga aacgaagcgc aggccagcgc
     3001 cctgaaaagt accgccgaca ccctgaatat catcagcgcc ggggtacagg atatgcagca
     3061 ggtgctggca caactccgcg cggaaaatca gcaacgcaat caggacggag aggccagacg
     3121 tgaacagcta cgcaacgata ttgcaaaaga tgaatgcgcc cacgctttgc ctgacgctcg
     3181 ttttactgac aggttgcgca ggcacgcaga acgcgccacg gccagcgccg tcagtccggc
     3241 ttataccgca gacgctgacc ataccggtaa tgcctccccc cttccctgat actcccacat
     3301 ggggaaatct cggtatatgg ggcgaccgcc ttctggatgc actggaaacc tgtaacgcgg
     3361 ataaacgggc cattgaatta ctggaacagc gccggctgca acgactgaac aacgaggaca
     3421 acaaccatgc tgaaaactga ttccctgcgt gaagccatga cccgttcatg ccgatggtgt
     3481 caggccaacc cggaaaaatt caccattttc gtggagagcg gcaacattga aacgaccgga
     3541 gaaacgccct cgtttgttta ccgctatcag atggtgatgt ttgtcatgga ttacgccggg
     3601 gagctggacg acctcacgct gccgctactg gcgtggttat ccgaaaatca gccacagttg
     3661 ttgctcaacc ctgagcgtaa tcaggacatc aaattctccg ccgttatcaa tgacgatgac
     3721 agcgccgatc tcctgtttac gctccccctg cgggaacgcg ttcgcattac gcgcaacagt
     3781 caggggacac cgcaggcaga acacctgccg gagccaaaac cccgtctgcc
//
LOCUS       DAZUDJ010000181         3830 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.185, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000181 DAZUDJ010000000
VERSION     DAZUDJ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3830
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.185"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..528
                     /locus_tag="ACHY1N_005080"
     CDS             <1..528
                     /locus_tag="ACHY1N_005080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P2 family phage major capsid protein"
                     /protein_id="HFS4047212.1"
                     /translation="WLEHIRTDASERVMNDVTLTSRNMDNTVAHAGKYANADALVQDA
                     RSSLLDEWHKEADDLVVIMGRNLFNSLRLPVLNSISGQNPNAELLAGQLILSSRTIGG
                     LGVFLAPFFPDATMLITSFNNLSIYWQKGSMRRLMKDEPEYNRIATYQSINDAYVVED
                     YGKCAMVTGLKFADS"
     gene            574..1374
                     /gene="gpM"
                     /locus_tag="ACHY1N_005081"
     CDS             574..1374
                     /gene="gpM"
                     /locus_tag="ACHY1N_005081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFS4047213.1"
                     /translation="MITPAQQHWQNVMAQRAGRANEGVDHAARTAHEEVLYRLRLAQA
                     RLKGVQARSAKAAIKKELLPDFSGWIEGTLEADGGQQDEVIATLMVWAIDCGDLPLAL
                     RIGAYVVRHNLIMPDNFGRTAATVLTEEICNPVLTQAGADADADLSAFIEPLDTLRKI
                     VTDQDMPDEVRAKLCKACAFARRGLTDADSMALSLKLLREAMHLNPNAGVKREIATLS
                     RALKKADSAAAPEDASAQQAQDESSKSKKTTRKPATRKTTATQKAKRG"
     gene            1476..1970
                     /locus_tag="ACHY1N_005082"
     CDS             1476..1970
                     /locus_tag="ACHY1N_005082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HFS4047214.1"
                     /translation="MSMVARTNPGPAEDDITDTDDGDTRISAGAFWPDIVLRELRLAI
                     RLPGRVTTSRLLHTATGAVAHVTRELEAWQQEQQAAGHQTLADVPAPVINGESVNLWH
                     WRNAVYTATRALILERYRDADTTDKGDRRADALDIQTSDLWRDVSWAISDILCRPRIF
                     AELC"
     gene            1970..2170
                     /locus_tag="ACHY1N_005083"
     CDS             1970..2170
                     /locus_tag="ACHY1N_005083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HFS4047215.1"
                     /translation="MKVKALEGDTVDSLCFRYYGTTQGVTEKVLDANPGLCQQVFLDA
                     GQDVEMPEPEKKKREMIQLWGE"
     gene            2173..2496
                     /locus_tag="ACHY1N_005084"
     CDS             2173..2496
                     /locus_tag="ACHY1N_005084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFS4047216.1"
                     /translation="MSTIQTGITEQVIAWLFDHLPTVYAVGAAVSISALMSLYDGRTL
                     VQTVTGSLACGVLAMAVAGSLRFFGFPEDAVTFIGASIGFMGAEKARDKVIAAFNRRV
                     KEKDE"
     gene            2493..2885
                     /locus_tag="ACHY1N_005085"
     CDS             2493..2885
                     /locus_tag="ACHY1N_005085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFS4047217.1"
                     /translation="MSNTFKFSSRSEKNLQGVNPDLVKVTRRALEISEVDFGITEGLR
                     SRYRQKQLVATGKSQTMNSRHLTGHAVDVVAYIGSQVSWEWPLYEKIAAAFRLASREL
                     NIPVEWGGDWKTLKDGPHFQLPHGAYPA"
     gene            2882..3289
                     /locus_tag="ACHY1N_005086"
     CDS             2882..3289
                     /locus_tag="ACHY1N_005086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2570 domain-containing protein"
                     /protein_id="HFS4047218.1"
                     /translation="MKLWPTLGVAFLLIAGWGTSMRLSWSLGRENARNEAQASTLKST
                     ADTLNIISAGVQDMQQVLAQLRVENQQRNQDGEVRREQLRNDIAKDECAHALPDARFT
                     DRLRRHAERATASAVSPAYTADADHTGNASPLP"
     gene            3427..>3830
                     /locus_tag="ACHY1N_005087"
     CDS             3427..>3830
                     /locus_tag="ACHY1N_005087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047219.1"
                     /translation="MLKTDSLREAMTRSCRWCQANPEKFTIFVESGNIETTGETPSFV
                     YRYQMVMFVMDYTGELDDLTLPLLAWLSENQPQLLLNPERNQDIKFSAVINDDDSADL
                     LFTLPLRERVRITRSSQGTPQAEHLPEPKPRLP"
BASE COUNT          896 a         1075 c         1139 g          720 t
ORIGIN      
        1 tggctggagc acatcagaac cgacgccagc gagcgcgtta tgaatgacgt gacgctgacc
       61 tcccgcaaca tggacaacac cgtggcgcac gcgggtaagt atgcgaacgc tgatgcactg
      121 gtacaggacg cacgctcatc cctgctggat gaatggcaca aggaagctga cgacctcgtg
      181 gtgattatgg ggcgcaacct gtttaactcg ctgcgtctgc ccgtgctgaa cagcatcagc
      241 ggccagaatc ccaatgcgga attacttgcc gggcagctca tcctgtcatc gcgcaccatt
      301 ggcgggctgg gcgtgttcct tgcgccgttc ttcccggatg caacgatgct gatcacctcg
      361 ttcaacaacc tgtcgattta ctggcagaaa ggttcaatgc gtcgcctgat gaaagacgag
      421 ccggaataca accgcatcgc cacctaccag tccatcaatg acgcttatgt cgttgaagac
      481 tatggcaagt gcgcgatggt cactggcctg aagttcgccg acagctaatc aactcacggc
      541 gggcatcatg cccgccagta acggagagaa caaatgatta ctcctgcaca gcaacactgg
      601 cagaacgtga tggcacagcg cgcaggccgg gcgaatgaag gcgtggacca cgccgcgcgt
      661 accgcgcatg aagaggtgct gtatcgtctg cgtctggcac aggcccggct taagggcgta
      721 caggccagaa gcgcgaaagc cgccatcaaa aaagagttgt tgccggattt ttccggctgg
      781 attgagggaa cgctggaggc tgacggcggg cagcaggatg aagtgattgc cacgctgatg
      841 gtgtgggcga ttgactgcgg cgatcttccg ctggcgttgc gtattggtgc gtatgtggtc
      901 cgtcataacc tcattatgcc ggataacttt ggccgtactg ctgccacagt gctgaccgaa
      961 gaaatctgca acccggtact gacgcaggcc ggggcggatg ccgacgcgga tttgtccgcc
     1021 tttatcgaac cactggacac cctccggaag attgtcaccg accaggacat gccggacgaa
     1081 gtacgcgcca aattatgcaa ggcgtgcgcc tttgcccgtc gtggtctgac cgatgcagac
     1141 agcatggccc tgtcactgaa gctgctgcgc gaagcgatgc acctgaaccc gaacgcaggt
     1201 gtgaaacgcg agattgcaac cctttcccgc gccctgaaaa aagccgattc cgcagccgca
     1261 ccagaagacg ccagcgcaca gcaggcgcag gacgaaagca gcaaaagtaa aaagacaacg
     1321 cggaagcctg caacacgaaa aaccaccgcg acgcagaagg cgaagcgcgg ttaacgactg
     1381 accccgtcag cgggcggcgt gcgcggtgtt ccggtttgac tccgtgaccg tttacaccgc
     1441 gcacccaccg cccgattttt tcaggagtga accccatgag tatggttgcc agaaccaacc
     1501 ccggccccgc agaggacgac atcaccgata ccgatgatgg tgatacccgt atttcagcgg
     1561 gtgcattctg gccggatatt gtgctgcgtg agctgcgtct ggcgatacga ctgccgggcc
     1621 gtgtgaccac ctcccgcctg ctgcataccg ccaccggggc tgtggcacac gttacccgcg
     1681 agctggaagc atggcagcag gaacagcagg cggctggcca tcagacgctg gccgatgttc
     1741 cggcacccgt aattaacgga gaaagcgtca atctctggca ctggcgcaat gctgtttata
     1801 ccgccacacg cgccctgatt ctggagcgtt accgcgatgc ggacacaacg gacaagggcg
     1861 accgccgggc ggacgcactg gatatacaga catcggattt gtggcgcgat gtgagctggg
     1921 ccatctctga cattctgtgc cgcccgcgaa tctttgcgga gttgtgctga tgaaagtgaa
     1981 ggcactggaa ggcgacaccg tggattcgct ctgtttccgg tactacggca cgacgcaggg
     2041 cgtcaccgaa aaggtgctgg atgccaaccc cggactctgt cagcaggtat ttctggacgc
     2101 cgggcaggac gtggagatgc cggagccgga gaagaagaaa cgagaaatga ttcagttgtg
     2161 gggggagtag cagtgagcac cattcaaaca gggatcacag agcaggttat tgcatggctc
     2221 tttgaccacc tgccaacggt gtatgcagta ggcgcggcgg tcagcatttc cgcgctgatg
     2281 agtctttatg acggacgaac actggttcag accgtaacgg gatcgctggc gtgcggcgtt
     2341 cttgccatgg ccgtggccgg gtcgttgcgc ttcttcgggt ttcctgaaga tgccgtgacg
     2401 tttatcggcg catcaatcgg ttttatgggt gcagagaaag cacgcgacaa ggttattgcg
     2461 gcctttaatc gcagggtgaa ggagaaggac gaatgagcaa cacatttaaa ttcagcagcc
     2521 ggagcgaaaa gaatttgcag ggcgtaaatc ctgatctggt gaaagtgacc cgacgggcac
     2581 tggaaatctc ggaagtggat tttggtatca ccgaagggtt gcgcagccgt taccgccaga
     2641 agcaactggt ggccacgggt aagagccaga ccatgaacag ccgccacctt acggggcatg
     2701 ccgtggatgt tgtggcttat atcggcagtc aggtgtcatg ggaatggccg ctgtacgaaa
     2761 aaatcgcagc agcattcaga ctggccagcc gggaactgaa tattccggtg gaatggggcg
     2821 gcgactggaa gactctgaaa gacggaccgc attttcagtt accacacgga gcctatccgg
     2881 catgaagctc tggcccacgc ttggcgtcgc tttccttctg attgccggat ggggaacatc
     2941 catgcgtctg tcgtggtcgc tgggccggga gaacgccaga aacgaagcgc aggccagcac
     3001 cctgaaaagt accgccgaca ccctgaatat catcagcgcc ggggtacagg atatgcagca
     3061 ggtgctggcg caactccgcg tggaaaatca gcaacgcaat caggacggag aggtaagacg
     3121 tgaacagcta cgcaacgata ttgcaaaaga tgaatgcgcc cacgctttgc ctgacgctcg
     3181 ttttactgac aggctgcgca ggcacgcaga acgcgccact gccagcgccg tcagtccggc
     3241 ttataccgca gacgctgacc ataccggtaa cgcctccccc cttccctgac actcccacat
     3301 ggggaaatct cggtatatgg ggcgaccgcc ttctggatgc actggaaacc tgtaacgcgg
     3361 ataaacgggc cattgaatta ctggaacagc gcaggctgca acgactgaac aacgaggaca
     3421 acaaccatgc tgaaaactga ttccctgcgt gaagccatga cccgttcatg ccgatggtgt
     3481 caggctaacc cggaaaaatt caccattttc gtggagagcg gcaacattga aacgaccgga
     3541 gaaacgccct cgtttgttta ccgctatcag atggtgatgt ttgtcatgga ttacaccgga
     3601 gagctggacg acctcacgct gccgctgctg gcgtggttat ccgaaaatca gccacagttg
     3661 ttgctcaatc cggagcgtaa tcaggacatc aaattctccg ccgttatcaa tgacgatgac
     3721 agcgccgatc tcctgtttac gctccccctg cgggaacgcg ttcgcatcac gcgcagcagt
     3781 cagggcacac cgcaggcaga acacctgccg gagccaaaac cccgcctgcc
//
LOCUS       DAZUDJ010000182         3809 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.186, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000182 DAZUDJ010000000
VERSION     DAZUDJ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3809
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.186"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            45..761
                     /gene="nanC"
                     /locus_tag="ACHY1N_005088"
     CDS             45..761
                     /gene="nanC"
                     /locus_tag="ACHY1N_005088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313297.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid outer membrane channel
                     NanC"
                     /protein_id="HFS4047220.1"
                     /translation="MKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYETRLK
                     VSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHF
                     SSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYVTYH
                     INSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQGV
                     YNGRDNLSENSYRIGVSFKL"
     gene            781..1887
                     /gene="nanM"
                     /locus_tag="ACHY1N_005089"
     CDS             781..1887
                     /gene="nanM"
                     /locus_tag="ACHY1N_005089"
                     /EC_number="5.1.3.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418730.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HFS4047221.1"
                     /translation="MNKTITALAIMMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
                     LGSAGTAWYKLDTQAKDKKWTALAAFPGGPRDQATSAFIDGNLYVFGGIGKNSKGLTQ
                     VFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNE
                     AGKDSATIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAALVNK
                     GDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLAPVSSPDGVAGGFAGISNDSLIF
                     AGGAGFKGSRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQGRAYGVSLPW
                     NNSLLIIGGETAGGKAVTDSVLISVKDNKVTVQN"
     gene            1952..2932
                     /gene="nanS"
                     /locus_tag="ACHY1N_005090"
     CDS             1952..2932
                     /gene="nanS"
                     /locus_tag="ACHY1N_005090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HFS4047222.1"
                     /translation="MNAIISPDYYYVLTVAGQSNAMAYGEGLPLPDREDAPHPRIKQL
                     ARFAHTHPGGPSCHFNDIIPLTHCPHDVQDMQGYHHPLATNHQTQYGTVGQALHIARK
                     LLPFIPDNAGVLIVPCCRGGSAFTAGSEGTYSERHGASHDACRWGTDTPLYQDLVSRT
                     RAALAKNPQNKFLGVCWMQGEFDLMTSDYASHPQHFNHMIEAFRRDLKQYHSQLNNIT
                     DAPWFCGDTTWYWKENFPHAYEVIYGNYQNNVLANIIFVDFQQQGERGLTNAPDEDPD
                     DLSTGYYGSAYRSPENWTTALRSSHFSAAARRGIISDRFVEAILQFWGEK"
     gene            complement(3000..3062)
                     /locus_tag="ACHY1N_005091"
                     /pseudo
     CDS             complement(3000..3062)
                     /locus_tag="ACHY1N_005091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012139841.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            3144..3287
                     /locus_tag="ACHY1N_005092"
                     /pseudo
     CDS             3144..3287
                     /locus_tag="ACHY1N_005092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_080685909.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
     gene            complement(3594..>3809)
                     /locus_tag="ACHY1N_005093"
     CDS             complement(3594..>3809)
                     /locus_tag="ACHY1N_005093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001443016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047223.1"
                     /translation="ASPAFAPSHLRTIGTSIDVNGRFFMTEIRATQGFSLFFAQPKST
                     YINLLMWIQLQLRLYPDSIMFVPTQNP"
BASE COUNT         1127 a          797 c          905 g          980 t
ORIGIN      
        1 cgggctttgt attgctttct gtatcctaca aatgagtgaa atttatgaaa aaggctaaaa
       61 tactttctgg cgtattatta ctgtgctttt cgtccccatt aatttctcag gctgcgacac
      121 tggacgtacg tggtggatat cgtagtggaa gccacgccta tgagactcga ctcaaagtca
      181 gtgagggatg gcaaaatgga tggtgggcaa gcatggaaag taatacctgg aataccattc
      241 atgataataa aaaggaaaat gccgcactca atgatgttca ggttgaagtt aattacgcga
      301 ttaaacttga tgatcaatgg acggtgcgcc cgggaatgtt aacgcatttt agcagcaacg
      361 gcacacgcta cggaccctac gtaaaactgt cctgggacgc gacaaaagat cttaattttg
      421 gcattcgcta tcgttacgac tggaaagctt accgacaaca agacttatcc ggtgatatgt
      481 ctcgtgataa cgttcatcgt tgggatggat atgtcactta ccatattaat agtgatttca
      541 ccttcgcatg gcaaacgacg ctatacagca aacagaacga ttatcgctat gcaaaccata
      601 agaaatgggc gacggaaaat gcatttgttc tacaatacca tatgacgccc gatattacgc
      661 catacataga atatgactac ctggaccgtc agggtgttta caacggcaga gataatttat
      721 cggaaaacag ttatcgcatt ggtgtgtcat ttaaactgta gtagacagga gacagtcaca
      781 atgaataaaa caataacggc gcttgctatc atgatggctt catttgccgc aaacgcgtct
      841 gtattacctg aaactcctgt gccatttaaa agtggtaccg gagcaattga taacgacact
      901 gtctacattg gtttaggtag cgcaggtacg gcatggtaca agctggatac acaggccaaa
      961 gataaaaaat ggacagcgtt agctgcattc cctggtggac caagagatca agcaacctcg
     1021 gcatttattg atggcaatct gtatgtgttt ggcggcattg gcaaaaatag caagggcttg
     1081 actcaggtat ttaatgacgt acacaaatac aaccccaaaa ccaatagttg ggttaaattg
     1141 atgtcgcatg caccgatggg catggcgggt catgtgactt ttgtacacaa cggcaaggct
     1201 tatgttactg gcggtgttaa ccagaatatc ttcaatggct attttgaaga tctcaacgag
     1261 gctggaaaag attcagcaac tatagacaag atcaatgccc attattttga caaaaaagca
     1321 gaagattatt tcttcaataa gtttctgttg tcttttgatc cctcaacaca gcaatggagt
     1381 tacgctggcg aatctccctg gtacggaacg gctggtgcgg cgcttgtgaa taaaggtgat
     1441 aaaacctggc ttattaatgg cgaagccaaa ccaggattgc gaacggatgc cgtatttgaa
     1501 cttgatttca ccggtaataa tttaaaatgg aataagcttg ctcccgtctc atcaccagat
     1561 ggcgtcgctg gcggttttgc ggggataagc aatgattctc ttatatttgc cggaggggcc
     1621 ggattcaaag gttcacgaga aaattaccag aacggtaaga actatgcgca tgaaggccta
     1681 aaaaaatcat atagcactga tattcatctt tggcataacg ggaaatggga taaatcgggt
     1741 gaattatcgc aaggtcgggc ctacggagta tcattgccct ggaataatag tctattgatt
     1801 attggcggtg aaactgcagg cggcaaagcg gtgacggatt cagttttgat ctctgtgaag
     1861 gataataaag tcacagtaca aaattaacgc ttcagggccc cggtaaaggg gccctgctat
     1921 caatttgtca tttcaattac gcgaaattta tatgaacgca ataatatcgc ccgattatta
     1981 ctatgttctt accgttgctg gtcagtctaa tgccatggcg tatggcgaag gactgccatt
     2041 accggacagg gaagatgcgc ctcatcccag aattaaacaa ttagcgagat ttgcgcatac
     2101 gcatcccgga ggcccgtcat gtcactttaa cgacattatt ccactgactc actgcccaca
     2161 cgatgttcag gatatgcagg gttatcacca tcctctggca acgaatcatc aaacacagta
     2221 cggcaccgtt ggccaggcac tgcatattgc acggaaatta ctacccttta ttcctgataa
     2281 tgcaggggtt ctcatcgttc catgttgccg tggcggatcg gcttttaccg cgggcagcga
     2341 agggacatat tcagaacggc acggagccag ccatgatgct tgtcgttggg gaacggatac
     2401 tccgctgtac caggatttag tcagcagaac gcgagccgca ctggcaaaaa atccgcagaa
     2461 caaattcctc ggcgtatgct ggatgcaagg cgaatttgac ttaatgacca gtgactacgc
     2521 gtcacaccct caacacttta atcatatgat tgaagccttt cgtagggatc taaaacaata
     2581 ccattctcag cttaataata ttactgacgc gccgtggttt tgcggcgata ccacctggta
     2641 ctggaaagaa aatttccctc atgcgtatga agttatttat ggcaattatc aaaataatgt
     2701 tttagccaat attattttcg tcgacttcca gcaacaaggt gaaagaggac tgacgaacgc
     2761 gcctgatgaa gacccggacg atttaagcac gggatattac ggttcagcgt accggtcacc
     2821 ggagaactgg acgacggcac tgcgaagcag tcatttcagc gcggcagccc gtcgggggat
     2881 tatttctgac aggtttgtag aagcaatttt gcagttttgg ggcgaaaagt gagcgttcat
     2941 taatttgatt tattcgcatc catcaacgct tttaactcct ccggcgtaaa cggtggttag
     3001 cgtcggtgca gcatcgcatg gcaattaggg tacacaggca gcaaaaaaac aaatgagatc
     3061 aaagtaatat atcttcactt gcaggcttga acagccgaaa atttgcgagc atgatcgcaa
     3121 ttatttcact gccagggata tcaatggctt ccagtaaatc gctacagcag gcaattgcca
     3181 atataaaaat ctggcacaag ggtgaacagc gcgcgccgca taagccattg ttattgctat
     3241 acgtattagc gggatacctg aatggacatc cacgcctttt cgattattgt agtggaacag
     3301 tctacgagga tgcagtttga agtgagtaag taaaggttgc tggaaacgat caatgccgcc
     3361 atacaatgat atttgaggat caccaatgag taataaaaac tacgaaagtc accgcaaagc
     3421 aatagttagt aaaggtatac cacccactct attaaatagg ctcaccaatt cggatgttca
     3481 ggtgatcaat accttcttaa cacgagtgag caaactggaa ctatctcaac aagagaaaga
     3541 ctggatcata aaaatcatct ctatggttta gagaatttca gccttgtagc ctttcaaggg
     3601 ttttgtgtgg gtacaaacat tatcgaatcg ggatatagcc gcagctgtag ctgtatccac
     3661 atcagtaagt tgatgtaggt tgacttaggt tgagcgaaaa atagcgaaaa gccttgtgtg
     3721 gcgcggattt cagtcataaa aaaacgtccg ttgacgtcta ttgatgttcc gatggtgcga
     3781 aggtgcgaag gtgcgaaggc cggactcgc
//
LOCUS       DAZUDJ010000183         3696 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.187, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000183 DAZUDJ010000000
VERSION     DAZUDJ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3696
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.187"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..118)
                     /locus_tag="ACHY1N_005094"
     CDS             complement(<1..118)
                     /locus_tag="ACHY1N_005094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047224.1"
                     /translation="MAKIQYLQGTHDARAGDIRDVAQPCAEVLVRLGKAEYIT"
     gene            complement(163..2100)
                     /locus_tag="ACHY1N_005095"
     CDS             complement(163..2100)
                     /locus_tag="ACHY1N_005095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFS4047225.1"
                     /translation="MTLKRACSLLTVKSFSEDERVITGIASTPSPDRDGDILEPEGAE
                     FGSAIPFLWQHDHSRPVGQCTVRRGREGLEITATLVKPVPDMPSQLAARLDEAWAAIK
                     TGLVRGLSVGFRAHEYTFLDGGGMHFLRWELMEVSAVTVPANAECTIQTIKSFDRPFS
                     AASGNRKPVVKTASSAGASAQSKTLFHKEKSAMNIGEQIKSFENKRAALAASLEEIMN
                     KAAEEGRTLDVEEEEHYDNTAAEIRQVDAHLKRLRELEAGKAATAQPVKQAGNGDVVT
                     VASAPVIRVEQKLDKGIGFARFAKSLAAAKGVRSEALEVARRQYPDDSRLHHVLKSAV
                     GAGTTTDPQWAGSLSEYQEYAQDFIDYLRPQTIIGRFGQGGIPALRQVPFNIRVHAQV
                     SGGAAGWVGEGKARPLTKFDFESITFSHAKVSAIAVLTEELIRFSSPAADALVRNALA
                     EAVVARLDTDFVDPKKAAVADVSPASITHDVKGTASSGNPDADAEAAFGQFVTANLQP
                     TGAVWLMSSTNALALSMRKNALGQKEYPDMTLLGGTFQGLPVIVSQYVGDQLVLVNAP
                     DIYLADDGGVAVDMSREASLEMQSEPTSDSSTPSPVELVSMFQTGSVAIRAERWINWR
                     RRRTAAVAVITGVNYGTASGG"
     gene            complement(2164..>3696)
                     /locus_tag="ACHY1N_005096"
     CDS             complement(2164..>3696)
                     /locus_tag="ACHY1N_005096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HFS4047226.1"
                     /translation="IVDAPGSPTFGESCAPWVFDLVAALFGSYDAQTGVRHIKEVFIL
                     IPKKNSKSTLAAGIMMTALLLNWRQAAGYTILAPTVEVAANAFNPARDMVRRDDDLDD
                     LCQVQTHIRTITHRVTDTTLKVVAADPNTVSGIKSVGTLIDELWLFGKQYKAEDMLRE
                     AIGGLASRPEGFVVYTTTQSNEPPAGVFRQKLQYARDVRDGKIHDPHFLPVIFEHPPE
                     MVESGAHLLMENLAMVNPNLGYSVDEAFLYREYRKAREAGEEAFRGFMSKHANVEIGL
                     ALRSDRWAGADFWEQQGRRVSLDDILQRADVVTVGIDGGGLDDLLGMYVIGRDRETRE
                     WLGWGHAWAHETAVVRRKSEASRFQDFVACGDMTIVRRVGDDTAEVAEYVRRIHEAEL
                     LEHIGIDPSGVGQILDSLAEAGIPDGIVVGISQGWKLGGAIKTTERKLAEGVLVHGGQ
                     PLMAWCVGNARVEPKGNAILITKQASGRGKIDPLMALFNAVSLMSLNPEPKKKEYAVF
                     FI"
BASE COUNT          771 a         1231 c          939 g          755 t
ORIGIN      
        1 ccgtgatgta ctccgccttc cccaggcgaa ccagcacctc cgcacacggc tgtgccacat
       61 cacggatatc cccggcccgg gcatcatgcg tgccctgcag atactggatt tttgccatca
      121 gttactgcgg gaagctcgcg cctcccgccc tcctcatcag actcagccgc cggacgcagt
      181 tccgtagttc acaccggtga tcaccgccac cgccgcagta cggcgacgac gccagttgat
      241 ccagcgctcc gcacggatgg ccacgctgcc ggtctggaac atggagacca gctccaccgg
      301 tgacggtgtg ctgctgtcgc tggtcggttc agactgcatc tccagtgacg cttcacggga
      361 catatccacc gccacaccac cgtcatcagc cagataaata tccggcgcat tcaccagtac
      421 cagctggtca cccacatact gggagacaat caccggcagc ccctggaagg tcccgcccag
      481 cagggtcatg tccggatatt ccttctgccc cagcgcattt ttacgcatgg acagcgccag
      541 ggcattcgtg ctggacatca gccagaccgc accggtgggc tgcagatttg ccgtcacaaa
      601 ctggccaaac gcggcctcgg catccgcatc cggattaccg cttgacgccg tgcccttcac
      661 atcatgggtg atggacgcag gggagacatc cgccaccgcc gcttttttcg gatcaacaaa
      721 gtctgtgtcc agacgtgcca ccaccgcctc tgccagcgca ttacggacca gtgcatcagc
      781 agccgggctg gaaaaacgga tcagctcttc cgtcagtacc gcaatggccg acaccttcgc
      841 atgactgaag gtaatggatt caaaatcaaa cttcgtcagg ggtctggcct taccctcacc
      901 cacccagccg gcagcaccgc cggacacctg ggcgtgcaca cggatattga acggaacctg
      961 acgaagggcc gggatccccc cctgaccaaa tcgcccgata atggtctgcg gacgcaggta
     1021 atcaataaag tcctgcgcat attcctggta ttcagacagg ctgcctgccc actgtggatc
     1081 tgtggtggtc cccgccccca ccgccgattt cagaacatga tgcagacggc tgtcatccgg
     1141 atactgacgg cgggccactt ccagggcttc ggagcggaca cctttagccg cggccagcga
     1201 tttggcaaaa cgtgcgaaac caatcccctt atccagtttc tgctccacac ggatcaccgg
     1261 cgcagaggcc accgtcacca cgtcaccgtt accagcctgt ttcaccggct gtgccgtggc
     1321 ggccttaccg gcttccagtt cacgcaggcg cttcaggtga gcatccacct gacggatttc
     1381 cgccgcggtg ttgtcgtagt gctcctcctc ctccacatcc agcgtgcggc cttcctctgc
     1441 ggctttgttc atgatctcct caagggaggc tgccagcgcc gcacgcttgt tttcaaaact
     1501 tttaatctgt tcaccaatat tcattgctga cttttcctta tgaaaaaggg tttttgactg
     1561 tgccgaagcg ccggcagaag atgctgtttt caccaccggt ttccggttgc cggacgcggc
     1621 agaaaacggt cggtcgaaag atttaatggt ctggatggtg cattccgcat tcgcaggaac
     1681 ggtgacggca gatacctcca tcagctccca gcgcagaaaa tgcattccgc ccccgtccag
     1741 aaaggtgtat tcatgggccc ggaagcccac agaaagcccc ctgaccagcc cggtcttaat
     1801 ggctgcccat gcctcatcca gtcgggctgc cagttgcgac ggcatatccg gtacgggctt
     1861 caccagcgtt gccgtgattt ccagcccttc cctgccccga cgcaccgtac actggcctac
     1921 cgggcgggaa tggtcatgct gccagagaaa cgggatcgca ctgccgaact ccgccccctc
     1981 cggctccagg atgtcaccat cccgatccgg agaaggcgtt gacgcaatcc cggtgatcac
     2041 ccgttcatcc tcactgaagg atttcaccgt cagcagggaa caggcccgtt taagagtcac
     2101 atcagcctcc tgaaaataaa aaaaccgccg gagcggttca tgatggttac agggtgaaca
     2161 gggttatatg aaaaaaaccg catattcttt ctttttcggt tccgggttga gggacatcag
     2221 ggagaccgca ttgaacagcg ccatcagcgg gtcaattttt ccccgtccac tggcctgttt
     2281 ggtgataaga atggcgttac ctttaggctc cacccgggca ttgccaacgc accaggccat
     2341 cagtggctga ccaccatgca ccagtactcc ctcagccagt ttgcgctcgg tggtttttat
     2401 ggccccgccc agcttccagc cctggcttat ccccacaaca attccgtcgg ggatcccggc
     2461 ttccgccagt gaatccagaa tctgccccac acctgacggg tcaataccga tatgctccag
     2521 taactcagcc tcatgaatac gacgcacata ctccgccact tccgccgtgt catccccgac
     2581 ccgacggaca atcgtcatgt ctccacaggc cacaaaatcc tgaaaacggg atgcctcact
     2641 cttccgtctg accaccgcgg tttcatgcgc ccaggcatgg ccccagccca gccattcgcg
     2701 ggtttccctg tcacggccaa tcacgtacat tcccagcaga tcatccaggc ccccgccgtc
     2761 aatccccacc gtcaccacat cagcgcgctg caggatatcg tccaggctga cgcgcctgcc
     2821 ctgctgctcc cagaaatccg cacccgccca gcggtcagaa cgcagggcaa gaccaatttc
     2881 cacattggca tgttttgaca tgaagccacg aaatgcttcc tcaccagcct cccgggcttt
     2941 acggtactcc cggtacagaa aagcctcatc caccgaataa ccgagattcg gattgaccat
     3001 ggcgaggttt tccatcagca ggtgagcccc gctttccacc atttcaggag ggtgttcaaa
     3061 tatcaccggc agaaagtgcg gatcatgaat tttgccgtca cggacatccc gggcgtactg
     3121 cagtttctgt ctgaacaccc cggcaggcgg ttcattcgac tgggtggttg tgtacaccac
     3181 aaatccttcc ggacgggagg caagcccgcc gatggcttca cgtagcatgt cttccgcttt
     3241 gtactgcttg ccaaacagcc acagttcatc aatcagtgtc cccacggact tgataccgga
     3301 caccgtattc ggatcggctg ccaccacctt cagggtggtg tccgtcaccc gatgggtgat
     3361 ggtccggata tgtgtctgca cctgacagag gtcatccaga tcatcgtccc gtcgtaccat
     3421 atccctggca gggttgaagg cgttggccgc cacctccacg gtcggggcca gaatggtgta
     3481 gcccgccgcc tgccgccagt tcagtaacag cgccgtcatc atgatccccg cagccagcgt
     3541 ggacttactg tttttcttgg ggataaggat aaacacttcc ttgatatggc gaacaccggt
     3601 ctgcgcatcg taggagccaa acagggccgc caccaggtca aacacccacg gtgcgcagga
     3661 ctccccgaac gtcgggctac ccggtgcatc cacaat
//
LOCUS       DAZUDJ010000184         3666 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.188, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000184 DAZUDJ010000000
VERSION     DAZUDJ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3666
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.188"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(43..180)
                     /locus_tag="ACHY1N_005097"
     CDS             complement(43..180)
                     /locus_tag="ACHY1N_005097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome C551"
                     /protein_id="HFS4047227.1"
                     /translation="MSGLEGFGTGFRSYVQAQGTLVNNTNLTDETGKVLNPATPEEIK
                     Y"
     gene            complement(219..449)
                     /locus_tag="ACHY1N_005098"
     CDS             complement(219..449)
                     /locus_tag="ACHY1N_005098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047228.1"
                     /translation="MKLFIFSLFVIVTSMVSGIAIAELSYFILLIIKYLAYGEVDFRW
                     SEVLRGLRMGCVGGGILGFGIVLFRFLGIKGF"
     gene            complement(446..1126)
                     /locus_tag="ACHY1N_005099"
                     /pseudo
     CDS             complement(446..1126)
                     /locus_tag="ACHY1N_005099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081256.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1166..1621)
                     /locus_tag="ACHY1N_005100"
     CDS             complement(1166..1621)
                     /locus_tag="ACHY1N_005100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047229.1"
                     /translation="MMYLLLGIALSAFTVGTVMFYRFSKVTGRSVQSPFTPMFFFDAL
                     FFGLGSRRDMNIAACAFMVFLLSVWGLTYIKLRTNFWGSPESYFGLGIVGIFFLIMHC
                     RYGAKDVVIKNDGLAPIRELINVHQSGLTSPFLWLSRAGYLGCLIGMIG"
     gene            complement(1626..2135)
                     /locus_tag="ACHY1N_005101"
     CDS             complement(1626..2135)
                     /locus_tag="ACHY1N_005101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001303001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin type 25 domain-containing
                     protein"
                     /protein_id="HFS4047230.1"
                     /translation="MPPRVQQDASLAFDLSGKGVTNDEIIKAVDKSHIGPSVGDTAKI
                     HGDVKGQVAGGYVAGGYLEGVLSEDKFSINGGVTKVLGWRADVSAGLTFGPYPIKDFN
                     PTYDYSGAISTGIFSVEGSIGKDGFGGSFRVGGGIGASIRQSENSNNQPEINGSGSTE
                     LISWPIKKD"
     gene            complement(2158..2415)
                     /locus_tag="ACHY1N_005102"
     CDS             complement(2158..2415)
                     /locus_tag="ACHY1N_005102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047231.1"
                     /translation="MKYSSRVVIGKFIICSSILLLCFIGMILAAIITKLTFVALAWFQ
                     SGIFEVLWSDIVYAAQLGGLGGGILGFCWVLLYLFRAKGFS"
     gene            complement(2412..>3666)
                     /locus_tag="ACHY1N_005103"
     CDS             complement(2412..>3666)
                     /locus_tag="ACHY1N_005103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019076112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="VENN motif pre-toxin domain-containing protein"
                     /protein_id="HFS4047232.1"
                     /translation="ARTQGELNALKAAKEATGETLPANATEKQRQEYLAKLRDTQAYR
                     NEMAKYGTGSEIQRGIQVAMAALQGLAGGNMAGALAGASAPELANIIGHHAGIDDNTA
                     AKAIAHAILGGVTAALQGNSAAAGAIGAGTGEVIASAIAKSLYPGVDPSKLTEDQKQT
                     VSTLATLSAGMAGGIASGDVAGAAAGAGAGKNVVENNLLGGSEDAQAAWIRQHGIDMA
                     TCAENPSGAACQKAMNERDAVGLALATGTVALLPGSAQAMWGLGASANAGISYLADGT
                     VDPANAAIAGWVNVFSMGNGLAGTVGWNAAGGALGNWIDNKDPLSGAISNGIGSAAGY
                     GIGKGVTWGTDKITNAVGKWVTNGWDPKYDPTWIKYAEVNRNDIIREGMKPSNVPGTA
                     GDIGGSIGSELGGKVTDKVSEELKK"
BASE COUNT          986 a         1073 c          647 g          960 t
ORIGIN      
        1 accttaactt aatgattttt accaaaatca ttaggggatt catcagtact taatttcctc
       61 tggcgttgcc ggattcagca ctttgccagt ttcatcagtg agattggtat tatttaccag
      121 cgtcccctgg gcctgaacat aactccggaa gccggtccca aacccttcca ggccagacat
      181 tgaattattc tcaacaacaa atcgtacctt atcttcactt aaaatccttt tatgccaaga
      241 aagcgaaaca agactatacc aaaacctaga attccacctc ccacacaccc catccttaga
      301 cctcttaaaa cttcggacca tctaaaatca acttccccat acgctaagta tttaatgata
      361 agcaatatga aataagacaa ctcagcaatt gcaattcctg aaaccatgga ggtaactatg
      421 acaaagagac tgaaaataaa tagtttcatt cacgctctcc tttcttcaat ttatcattaa
      481 tgactttttg tagttcagtc cccgtcattt ctgatgtaat agaagccccc atattacctg
      541 cagcccccgg aatcttgctc ggcaccattt ctttggagat acctaactgc cctttaactt
      601 cagtatattt tagtagagtc ggatcgaatt taggattcca gccaccggtt atccacttgc
      661 ctgctgtatt tgcaacaggc ttcaccacat aattgccaac cccatatcca aacccggccc
      721 ccgctccatt tgtaatcgcc ccagtaagag gctcatctcc gtttatagcg ttggttaatg
      781 ctccacctgc cgcattccag gctattgtcc ctttccagcc ctgccccatg gttatcacat
      841 ttatccagcc tgctgccact gagttgaccg ggtttatttc accactatct gcatactgca
      901 tcccggcatt tgtcccggca ccaagtaacc acatagcctg ggcactcccc ggtaacaggg
      961 caacgctgcc tgttgctaat gcggcagcat aagctttatt ttcagcctgc ccccgcttac
     1021 aggcttcacc ggaaggatta tcactacagg agagaacatc agcgccatgc tctctggctt
     1081 tttccgtctg gagccattca ctgccaccca gcaggttatt ctcaacaact aattggcatt
     1141 tatcacaaat ttcattaaca ctgcatcagc ctatcatgcc aattaaacat ccgaggtacc
     1201 ctgccctact taaccacaaa aatgggctgg tgaggccaga ctgatgaaca ttaattaact
     1261 cccttattgg tgcaagacca tcatttttga taacaacatc ctttgcacca tagcgacaat
     1321 gcattatcag aaagaaaatt ccgacaatcc ctaaaccaaa ataactttct gggcttcccc
     1381 aaaaattagt ccgtaatttt atataggtga gcccccaaac actcagtaaa aagaccataa
     1441 aagcacaggc agcaatattc atatcgcgtc tgctgcctag cccaaaaaat agagcatcaa
     1501 aaaaaaacat tggggtaaaa ggtgattgca cgcttcttcc tgtcacttta ctaaatcgat
     1561 aaaacatgac cgttccgaca gtaaaagcag aaagtgcaat acctaacagc aagtacatca
     1621 tttggttagt ccttttttat aggccaagaa attagttcgg tactaccaga accgttaatt
     1681 tccggctgat tattactgtt ttcactttgt cgaatactcg caccaattcc tccaccaact
     1741 ctgaaagagc cgccaaagcc gtctttacca atactccctt caactgaaaa aatacctgtc
     1801 gatatagcac cagaataatc ataagtagga ttaaaatctt taatcgggta aggcccaaaa
     1861 gtcaacccgg cagacacatc tgcacgccag cctaatacct tcgtgacccc gccattaatt
     1921 gaaaatttat cctctgacag tacaccttcc agataccctc ctgcgacata acctccagcg
     1981 acctggcctt ttacatctcc atgtattttt gccgtatcac ctactgacgg gccgatatgt
     2041 gatttgtcta ccgctttgat aatttcatcg ttagtgactc ctttaccact gagatcaaaa
     2101 gccagggaag catcctgctg tacgcgaggc ggcacaagct cagacagcgc attattctca
     2161 actaaagccc tttgccctaa aaagatataa caaaacccaa caaaaaccta atatgccccc
     2221 ccccagacca cccaactgag cagcataaac aatatcgctc cacaaaactt caaaaatccc
     2281 gctttgaaac catgctaacg ctacaaacgt tagtttagtt attatggccg ctaagatcat
     2341 gccaataaaa cacaataaga gaattgaact gcatataata aacttaccta ttaccactcg
     2401 agaagaatat ttcatttctt gagttcctca gatactttat ctgttacttt tccacctagc
     2461 tcagatccta tagaaccgcc aatatctcca gcagttccag gaacattgct cggtttcatg
     2521 ccttctcgaa tgatatcgtt acgatttact tcagcatatt ttatccatgt tggatcgtac
     2581 ttaggatccc agccatttgt cacccatttt cctacagcat tcgtaatctt atctgtcccc
     2641 caagtaacac ctttaccgat accatacccg gcagcagaac cgataccatt tgaaattgca
     2701 ccagacagag gatctttgtt gtcgatccag ttacccagcg caccacctgc cgcattccag
     2761 cccacagtcc ccgccaggcc attacccatg ctgaacacat tcacccagcc tgcaatggct
     2821 gcgtttgccg gatctacagt accatcagcc agataactga taccagcatt cgcacttgct
     2881 cccagtcccc acatagcctg agcactaccg gggagtagtg ccactgtacc tgttgccaga
     2941 gccagcccta cagcatccct ctcattcatt gctttctggc aggcggcacc ggaagggttt
     3001 tctgcacatg tcgccatgtc gataccatgc tggcgtatcc acgcagcctg agcatcttca
     3061 ctaccgccaa gtaaattatt ctcaacaacg ttcttcccgg caccagcccc agcagccgcg
     3121 ccagccacat cgccactggc aataccgccg gccatacccg ctgacagcgt tgccagcgtg
     3181 cttacagttt gcttctgatc ttctgtcagt ttcgacggat ctacgcccgg gtagaggctt
     3241 ttcgcaatgg ctgacgcgat cacttcgcca gtacccgcgc caattgcgcc tgctgccgca
     3301 ctgttgccct gaagggctgc tgtcacacca ccgagaatgg catgggcaat ggcttttgcc
     3361 gctgtattgt catcaatacc cgcgtgatga ccgatgatgt tcgccagctc cggcgctgaa
     3421 gcacctgcca gcgcgcctgc catattgccg cccgccaggc cctgaagcgc tgccatcgcg
     3481 acctggatac cccgctgaat ttcactacca gtgccatact tcgccatttc attcctgtaa
     3541 gcctgcgtgt cacgcagttt cgcaagatat tcctgacgtt gtttctctgt tgcattagca
     3601 ggaagtgttt cgccggttgc ttccttcgcg gccttcaacg cattcagttc tccctgtgta
     3661 cgcgca
//
LOCUS       DAZUDJ010000185         3595 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.189, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000185 DAZUDJ010000000
VERSION     DAZUDJ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3595
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.189"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(652..3000)
                     /gene="nleL"
                     /locus_tag="ACHY1N_005104"
     CDS             complement(652..3000)
                     /gene="nleL"
                     /locus_tag="ACHY1N_005104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector E3 ubiquitin
                     ligase NleL"
                     /protein_id="HFS4047233.1"
                     /translation="MLPTTNISVNSGVISFESPVDSPSNEDVEVALEKWCAEGEFSEN
                     RHEVASKILDVISTNGETLSISEPITTLPDLLPGSLKELVLNGCTELKSINCLPPNLS
                     SLSMVGCSSLEVINCSIPENVINLSLCHCSSLKHIEGSFPEALRNSVYLNGCNSLNES
                     QCQFLAYDVSQGRACLSKAELTADLIWLSANRTGEESAEELNYSGCDLSGLSLVGLNL
                     SSVNFSGAVLDDTDLRMSDLSQAVLENCSFKNSILNECNFCYANLSNCIIRALFENSN
                     FSNSNLKNASFKGSSYIQYPPILNEADLTGAIIIPGMVLSGAILGDVKELFSEKSNTI
                     NLGGCYIDLSDIQENILSVLDNYTKSNKSILLTMNTSDDKYNHDKVRAAEELIKKISL
                     DELAAFRPYVKMSLADSFSIHPYLNNANIQQWLEPICDDFFDTIMSWFNNSIMMYMEN
                     GSLLQAGMYFERHPGAMVSYNSSFIQIVMNGSRRDGMQERFRELYEVYLKNEKVYPVT
                     QQSDFGLCDGSGKPDWDDDSDLAYNWVLLSSQDDGMAMMCSLSHMVDMLSPNTSTNWM
                     SFFLYKDGEVQNTFGYSLSNLFSESFPIFSIPYHKAFSQNFVSGILDILISDNELKER
                     FIEALNSNKSDYKMIADDQQRKLACVWNPFLDGWELNAQHVDMIMGSHVLKDMPLRKQ
                     AEILFCLGGVFCKYSSSDMFGTEYDSPEILRRYANGLIEQAYKTDPQVFGSVYYYNDI
                     LDRLQGRNNVFTCTAVLTDMLTEHAKESFPEIFSLYYPVAWR"
     gene            complement(3020..3109)
                     /locus_tag="ACHY1N_005105"
     CDS             complement(3020..3109)
                     /locus_tag="ACHY1N_005105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047234.1"
                     /translation="MPINLTSYLWVQGQKVVPAVVFSNFTLVD"
     gene            complement(3122..3214)
                     /locus_tag="ACHY1N_005106"
                     /pseudo
     CDS             complement(3122..3214)
                     /locus_tag="ACHY1N_005106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309586.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
     gene            complement(3216..3485)
                     /locus_tag="ACHY1N_005107"
     CDS             complement(3216..3485)
                     /locus_tag="ACHY1N_005107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047235.1"
                     /translation="MNILKKLMQRLCGCGKHDDRENGELLTAQLRLGPADILESDENG
                     IIPEQDRVITQVVILDADKKQIQCVVRPLQILRADGTWENIGGMK"
     gene            complement(3487..>3595)
                     /locus_tag="ACHY1N_005108"
     CDS             complement(3487..>3595)
                     /locus_tag="ACHY1N_005108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047236.1"
                     /translation="VQGFFQHLQVRFGDGPWQDVKGLDEVGSDTGRTGE"
BASE COUNT         1197 a          792 c          526 g         1080 t
ORIGIN      
        1 tatagttgag aatgaaccat gagtacgact tgttggcagt atatagtttg ttattttcat
       61 taaaattcca cttcctctta taacgcacta ttcaatgaat aaaagccagt tgagagtctt
      121 ttcaaaacaa tcattaatta cgccatatta ctatagtaac aaaaacatat taatctgaat
      181 atcaattcat aaaatatgat tctccacgat ttgcccagaa ataacgaaca taattttcgt
      241 tgtaattaaa atcatatttc atctatagtg accattcaca gcaaaacaaa atcaattatc
      301 acattcaaaa aaaatactga caacaaagat actcttcaga caaagttgtc atatgtaaat
      361 tttcccttaa aacgttgctc aaaaaaaata taaaaatcat atgccctaat caacatcctc
      421 aagcactacg atatatgcag tatcctattc atatattacc accatatcag acaaatcgaa
      481 tcacaacgag ttctatcgta ctctttcatc ttcgacactg taaattttaa gaacattcgg
      541 ctcatgccac taaaccaaga cataataaca acggagcaat aaatgttccc actgaacatg
      601 tgcaaaccta aaaagacagt gttacaataa tattcatcca tggtctctaa atcaacgcca
      661 cgcaacagga taatacaatg aaaatatttc aggaaaagat tcttttgcat gctccgttag
      721 catatcagtc agcacagcgg tacaagtaaa aacattattt cttccttgta gcctgtctaa
      781 aatatcattg taataataaa ctgagccaaa tacctgagga tctgttttat aagcttgttc
      841 aatcaatcca tttgcatatc tccgtagaat ctcaggagaa tcatactctg taccaaacat
      901 atcactcgat gagtatttac agaaaacccc ccctaaacaa aataatattt cagcctgttt
      961 tcttagtggc atatctttca atacatggct ccccataatc atatctacat gctgagcgtt
     1021 cagttcccaa ccatcaagaa agggattcca gacacaggca agtttccttt gctgatcatc
     1081 agcaatcatt ttataatctg atttattgga attaagtgcc tcaataaatc tctctttgag
     1141 ttcattatca gaaatgagta tatccagaat accagaaacg aaattctggg aaaaagcttt
     1201 atgataagga atactgaaaa ttggaaatga ttcagaaaaa agattgctca atgaataccc
     1261 aaatgtattt tgaacttctc catccttata taaaaaaaag gacatccagt tagttgatgt
     1321 attaggagat aacatatcaa ccatatgact caaagaacac atcattgcca taccatcatc
     1381 ctgtgatgat aacaaaaccc agttataagc caaatcggaa tcatcatccc agtcaggctt
     1441 cccagagcca tcgcacaatc caaaatcact ctgctgtgtg acaggataaa ctttttcatt
     1501 ttttaaatat acttcataga gttccctaaa tcgttcctgc attccatcac gccgtgaacc
     1561 attcattaca atttgtataa aggaactatt ataagatacc atcgcacctg gatgtcgctc
     1621 aaaatacatc cctgcctgca ataaactacc attctccata tacatcatta ttgaattatt
     1681 aaaccaagac attatagtat caaaaaagtc atcacatata ggctcgagcc attgctgtat
     1741 atttgcgttg ttcaaataag gatgaatact aaatgaatca gccaaagaca tcttaacata
     1801 gggccggaac gccgctaatt cgtcaagaga tatttttttg ataagttctt cagcggccct
     1861 tactttatca tggttatact tatcatcaga tgtattcata gtcaataaaa ttgatttatt
     1921 tgattttgta tagttatcca acacagataa tatattttcc tgtatgtcag atagatctat
     1981 gtaacaccct cctagattaa tggtattact tttttcacta aagagctcct ttacatcacc
     2041 taagatagca ccacttaaaa ccattccagg aattataata gctcctgtta aatcagcctc
     2101 gttcaaaatt ggaggatatt gtatatatga agatccttta aatgatgcat ttttaagatt
     2161 ggaattgctg aaattagagt tttcaaacaa agccctaata atacaattag ataaattagc
     2221 ataacaaaaa ttacattcat tcaaaatcga gtttttaaaa gaacagtttt ccaatacagc
     2281 ctgagacaaa tcactcatcc tgagatctgt atcatcaagc actgctccag aaaaatttac
     2341 tgatgataaa ttcagcccta caagacttag acctgacaag tcacatccag agtaattcaa
     2401 ttcttcagca gactcttcac ccgttcggtt agccgacaac caaattaagt cagcagtaag
     2461 ctcagctttg ctcaggcagg cacggccttg actgacatca tatgcaagga attgacattg
     2521 cgattcattt aatgaattac agccatttaa atatacggaa tttctgagtg cctcaggaaa
     2581 ggaaccttct atatgtttca aagaactaca atggcataaa gataaattaa tgacattttc
     2641 aggtatgctg caatttataa cctctaatga tgagcatcca accatactta atgaagataa
     2701 gttggggggt aagcagttta ttgatttaag ctctgtacat ccattcaaaa ccagttcttt
     2761 cagagaacct ggaagcaagt ctggtaatgt tgttattggc tcactgattg ataaagtctc
     2821 tccattagta cttataacat caagtatttt tgatgcaacc tcatgacgat tttcgctaaa
     2881 ttctccctca gcgcaccact tttcgagggc aacttcaaca tcctcgttag atggtgaatc
     2941 tacaggactt tcaaaagata ttactccaga atttacagag atatttgtag tgggcagcat
     3001 ttatctcact cctttttact tagtccacta aagtaaaatt agaaaacaca actgccggga
     3061 caactttctg tccctgtacc cacaaataag atgtcagatt tatcggcatt aatttaactc
     3121 cctattgaat tatctcctct tttttatcta acaaatattc cccggacatg acaacaaaaa
     3181 ccggagccgg actccggttt tgtgaagctg tcgggttact tcatcccgcc aatattttcc
     3241 cacgtcccgt cagcacgcag gatttgcagc ggtcttacca cgcactgtat ctgcttttta
     3301 tccgcatcca gtatcaccac ctgcgtgatt accctgtcct gctccgggat aatgccattc
     3361 tcatctgact ccaggatgtc tgccggcccc agtcgcagct gtgctgtaag taactccccg
     3421 ttttcacggt catcatgctt tccgcaaccg cacagacgct gcataagttt ttttagtata
     3481 ttcatgtcat tctcctgttc tgcctgtatc actgcccact tcatccagcc ccttgacatc
     3541 ctgccacggc ccgtcgccaa atctgacctg caaatgctga aaaaaaccct gaacc
//
LOCUS       DAZUDJ010000186         3456 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.190, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000186 DAZUDJ010000000
VERSION     DAZUDJ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3456
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.190"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..494)
                     /locus_tag="ACHY1N_005109"
     CDS             complement(<1..494)
                     /locus_tag="ACHY1N_005109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein E"
                     /protein_id="HFS4047237.1"
                     /translation="MGLFTTRQLLGYTEQKVKFRALFLELFFRRTVNFHTEEVMLDKI
                     TGKTPVAAYVSPIVEGKVLRHRGGETRVLRPGYVKPKHEFNYQQAVERLPGEDPAQLN
                     DPAYRRLRIITDNLKQEEHAIVQVEEMQAVNAVLYGKYTMEGDQFDTVEVDFGRSEGN
                     NIEQA"
     gene            complement(552..899)
                     /locus_tag="ACHY1N_005110"
     CDS             complement(552..899)
                     /locus_tag="ACHY1N_005110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HFS4047238.1"
                     /translation="MVTKTITEQRAEVRIFAGNDPAHTATGSSGISSATPALTPLMLD
                     EATGKLVVWDGQKAGSAVGILVLPLEGTETVLTYYKSGTFATEAIRWPDSVDEHKKAN
                     AFAGTALSHTALP"
     gene            complement(936..2441)
                     /locus_tag="ACHY1N_005111"
     CDS             complement(936..2441)
                     /locus_tag="ACHY1N_005111"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HFS4047239.1"
                     /translation="MRRNLSHIIAAAFNEPLLLEPAYARVFFCALGREMGAASLSVPQ
                     QQVQLDAPGMLAETDEYMAGGKRPARVYRVVNGIAVLPVTGTLVHRLGGMRPFSGMTG
                     YDGIVACLQQAMADSQVRGVLLDIDSPGGQAAGAFDCADMIYRLRQQKPVWALCNDTA
                     CSAAMLLASACSRRLVTQTSRIGSIGVMMSHVSYAGHLAQAGVDITLIYAGAHKVDGN
                     QFEALPAEVRQDMQQRVDAAHRMFAEKVAMYTGLSVEAVTGTEAAVFEGQSAIKAGLA
                     DELINASDAISVMAAALNTHDTGGTMPQLTATEAAAQENQRVMGILTCQEAKGREQLA
                     TMLAGQQGMSIEQARAILAAAAPQQPVASAQSEADRIMACEEAKGREQLAATLAAMPE
                     MTVEKARPILAASPQANAGPSLRDQIMALDEAKGAEAQAEKLAACPGMTVENARAVLA
                     AGSGKAEPVSASTTALFEHFMANHSPAAVRGGVSQTSADGDADVKMLMAMP"
     gene            complement(2431..>3456)
                     /locus_tag="ACHY1N_005112"
     CDS             complement(2431..>3456)
                     /locus_tag="ACHY1N_005112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4047240.1"
                     /translation="VEVDRYGRAVAYHICEDDFPRSGSGRWERIPRELPTGRPAMLHI
                     FEPVEDGQTRGANQFYSVMERLKMLDSLQATQLQSAIVKAMYAATIESDLDTEKAFEY
                     IAGAPQGQKDNPLINILDKFSTWYDTNSVTLGGVKIPHLFPGDDLKLQTAQDSDNGFS
                     ALEQALLRYIAAGLGVSYEQLSRDYSKVSYSSARASANESWRYFMGRRKFIASRLATQ
                     MFSCWLEEALLRGIIRPPRARFDFYQARSAWSRAEWIGAGRMAIDGLKEVQESVMRIE
                     AGLSTYEKELALMGEDYQDIFRQQVRESAEREKAGLSRPVWIAQAYQQQIAESRRPEE
                     ETTPRET"
BASE COUNT          715 a         1091 c          877 g          773 t
ORIGIN      
        1 gcctgctcaa tgttatttcc ttcagagcgc ccgaaatcca cctcgacagt atcaaactga
       61 tccccttcca tggtgtattt gccatacagc acggcattca ccgcctgcat ttcttccacc
      121 tggacaatgg cgtgctcttc ctgtttgagg ttatcggtga tgatacgcag acgacggtag
      181 gccgggtcgt tcagctgagc cggatcttca ccaggaaggc gctcaaccgc ctgctggtaa
      241 ttaaattcgt gtttgggctt gacgtagccc ggacgtaaca cgcgggtttc accaccgcga
      301 tggcgaagca cttttccttc aacgatcggg gagacatagg ccgccaccgg cgtttttccg
      361 gtaattttgt ccagcatcac ctcttcggtg tggaaattca ccgtacggcg gaaaaacagc
      421 tccagaaaca gcgcacggaa tttcactttt tgttcggtat aaccgagtaa ctggcgggtc
      481 gtaaacaatc ccataaatca gttcctttca ttcagaaatc agtcaggccg ccatggtggc
      541 ctgataacgt gttacggcag agccgtgtga ctcagggctg tgccggcaaa ggcgttggcc
      601 tttttgtgtt catccacact gtcaggccag cggattgcct ccgtcgcaaa ggtccccgac
      661 ttgtaatagg tcagcaccgt ctctgtgcct tcaagcggca gtaccagtat gccaaccgca
      721 ctaccggctt tctgtccatc ccagaccacc agtttcccgg tggcttcatc cagcatcagg
      781 ggcgtcagag ccggtgttgc agaagaaatc ccgctgctgc ctgtggcggt atgagccgga
      841 tcattaccgg caaaaatacg tacttccgca cgctgttcag tgatggtttt cgtcaccatt
      901 ttgttaaaac ctcatattga tggtcagcac tgacttcatg gcatggccat gagcattttc
      961 acgtccgcat caccgtctgc tgacgtctgt gacacgccac cccgcaccgc tgccggtgaa
     1021 tgattcgcca tgaaatgttc aaacagggcg gttgtggatg cagagaccgg ttcggcctta
     1081 cctgatcccg cagccagcac agcccgggcg ttctccacgg tcattcccgg gcaggccgcc
     1141 agtttttcag cctgcgcttc tgcccctttt gcctcatcca gggccatgat ctgatcacga
     1201 agtgagggcc cggcattcgc ctgcggtgag gcagccagga tcgggcgggc tttttccacc
     1261 gtcatctccg gcatcgccgc cagcgttgcc gccagttgtt cacgaccttt cgcttcttca
     1321 cacgccataa tgcgatcggc ttcactctgc gcggatgcca ccggctgctg tggtgccgcc
     1381 gcggccagaa tcgcccgggc ctgttcaatg ctcatgccct gttgtcctgc cagcatcgtg
     1441 gcaagctgtt cacgtccttt cgcttcctga cacgtcagga tccccatcac tcgctggttc
     1501 tcctgcgcgg cagcttccgt tgcagttaat tgcggcatag tgcctcctgt atcatgagtg
     1561 ttcagcgccg cagccatcac gctgatggca tccgacgcat tgattaattc atccgccagt
     1621 ccggccttaa tagcggactg accttcaaaa acggcagcct ctgtccccgt gacagcttcc
     1681 acagacagcc ccgtatacat cgccactttt tcggcaaaca tccggtgcgc cgcatcaacc
     1741 cgctgctgca tgtcctgacg cacctctgcc ggtaaggctt caaactgatt gccatccacc
     1801 ttgtgcgccc cggcataaat cagcgtgata tccaccccgg cctgcgccag atgaccggca
     1861 tagctgacat ggctcatcat cacgccaatg gagccgatac gggatgtctg ggtaaccagc
     1921 cgtcgggagc aggccgacgc cagcagcatg gctgcagaac aggccgtgtc attgcacagt
     1981 gcccagaccg gcttctgctg acggaggcgg taaatcatgt cagcgcagtc aaacgcgccg
     2041 gcggcctgcc cgcccggact gtcaatgtcc agcagtacgc cccgcacctg gctatctgcc
     2101 attgcctgct gaagacaggc gacaatgccg tcatagccag tcattccgga aaatggccgc
     2161 ataccgccca gccggtgcac cagcgtgccg gtcaccggca gtacagcaat accgttcacc
     2221 acccggtaaa cacgggccgg tcgtttacct ccggccatgt actcgtccgt ttcagccagc
     2281 attccgggag catcaagctg tacctgttgt tgtggtaccg aaagacttgc tgcccccatc
     2341 tcgcgcccga gcgcgcaaaa gaaaacccgc gcataggcgg gctccagaag cagcggttca
     2401 ttgaatgctg cggcaataat gtgtgaaaga ttacgtctca cgtggtgttg tctcctcttc
     2461 cggcctgcga ctctccgcta tctgctgctg atacgcctgc gctatccaca ccggacgtga
     2521 gagtccggct ttttcccgct ctgcagattc cctgacctgc tggcggaaaa tgtcctgata
     2581 atcctcgccc atcagcgcca gctctttctc atacgtgctc agtccggcct caatgcgcat
     2641 cactgattcc tgaacctcct tgagcccgtc aatggccatt cttccggctc caatccactc
     2701 agcccgtgac caggctgatc gcgcctgata aaaatcaaaa cgtgcccgtg gcggacgaat
     2761 aatcccccga agaagtgcct cttccagcca gcaggaaaac atctgcgtgg ccagccggga
     2821 cgcaataaat tttcgccgcc ccataaaata gcgccacgac tcattggcgg atgcgcgggc
     2881 acttgaataa ctgaccttcg agtaatcacg ggacaactgt tcgtaggaaa cgccaagacc
     2941 ggcggcgata taccgcagca gcgcctgttc aagcgccgaa aatccattgt ctgaatcctg
     3001 cgcggtctga agtttcagat catcaccggg gaaaaggtgc ggaattttga caccgcccag
     3061 cgtcacgcta ttcgtgtcat accaggtgga gaacttatcc agaatattaa taagcggatt
     3121 atccttctgc ccctgcggcg cgccggcgat atattcaaag gccttttcgg tatcaaggtc
     3181 actttcaatc gtcgctgcat acatcgcctt cactatggcc gactgaagct gtgttgcctg
     3241 cagggaatcg agcatcttca gccgttccat gacgctgtaa aactgattgg ccccacgggt
     3301 ctgcccgtcc tccaccggct cgaaaatatg cagcatggcc ggacgcccgg tgggaagttc
     3361 acgcgggatc cgttcccatc gtccactccc ggagcgagga aaatcatcct cacagatatg
     3421 gtacgcaacg gcacgaccat atcgatcaac ctccac
//
LOCUS       DAZUDJ010000187         3450 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.191, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000187 DAZUDJ010000000
VERSION     DAZUDJ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3450
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.191"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            71..724
                     /locus_tag="ACHY1N_005113"
     CDS             71..724
                     /locus_tag="ACHY1N_005113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EspJ family T3SS effector
                     ADP-ribosyltransferase"
                     /protein_id="HFS4047241.1"
                     /translation="MPIIKNCLLSISNILHNEKTSYSLIKTEQTGKLLNRKITTTPTP
                     AKLLSYRNADLIKENYITEKVLSIFNIKRDFVAVRIQSNQFTDLKNKTIQGHKDTVAK
                     VMDWYNPQKNAFGIMMGTPRRSADIAKEESRNALNFMIMEKDTFNEKILNSNDNLQKK
                     YGTTENSSWVSASVGSLLDKGAKVYPDISCSLRLGEPFIITLPETVRLDVDIHPLKK"
     gene            complement(737..1435)
                     /locus_tag="ACHY1N_005114"
     CDS             complement(737..1435)
                     /locus_tag="ACHY1N_005114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047242.1"
                     /translation="MNEIRSNPVKFLEEHLILNPQRYAHHDETSLITVNITREDGLLR
                     LKETEDDMAGSDYILFTGMRDTDSPDRFDAPAVVSLSNQCISLRRNDISQTIQQISPL
                     WLTNQQSGCSVLIVRHGLSESGEQSYSMIHMRPRDSNDFVDEFTPALYANTQEILLER
                     DIQRTLANTFPNEHPEALILVPSAEKFIVDGNSIQLIGIGNELGEFDFYRQIYPVTGG
                     EHLVEALMWTHLPA"
     gene            complement(1636..2217)
                     /locus_tag="ACHY1N_005115"
     CDS             complement(1636..2217)
                     /locus_tag="ACHY1N_005115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002430189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004842 - ubiquitin-protein transferase
                     activity [Evidence IEA];
                     GO_process: GO:0044403 - biological process involved in
                     symbiotic interaction [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector NleG family protein"
                     /protein_id="HFS4047243.1"
                     /translation="MPLTSDINSSSFHLGMEVLRAQVAATGRGEFTMGGETVRIEYSP
                     TDGRFLASDGTGGLFTELLLLGFNNGPQALGERMLSILSGSDAGETQSQVTPQDKIYQ
                     CKFSVNTESLQCPSDATRCPIILETPEEGVFVKNSDSSAVCTLFDVDALSRVVNDGSV
                     HPLTRAPITPSMIVKPEECKYDPARGSFIIKDS"
     gene            complement(2286..2423)
                     /locus_tag="ACHY1N_005116"
                     /pseudo
     CDS             complement(2286..2423)
                     /locus_tag="ACHY1N_005116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309256.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
     gene            complement(2644..2793)
                     /locus_tag="ACHY1N_005117"
                     /pseudo
     CDS             complement(2644..2793)
                     /locus_tag="ACHY1N_005117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309257.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3111..3380)
                     /locus_tag="ACHY1N_005118"
     CDS             complement(3111..3380)
                     /locus_tag="ACHY1N_005118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047244.1"
                     /translation="MNILRKLMERLCGCGKHDDCEHGQSLTVQLRLGPADILESDENG
                     IIPEQDRVITQVVILDADKKQIQCVVRPLQILRADGTWENIGGMK"
     gene            complement(3382..>3450)
                     /locus_tag="ACHY1N_005119"
     CDS             complement(3382..>3450)
                     /locus_tag="ACHY1N_005119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047245.1"
                     /translation="DGPWQDVKGLDEVGSDTGRTGE"
BASE COUNT         1049 a          845 c          583 g          973 t
ORIGIN      
        1 atagcaatta gtttatataa tataagactt cctatcaaaa gttcatccat atgaagacaa
       61 ggaatttatt atgccaatca taaagaactg cttattatca attagtaaca tattacacaa
      121 cgaaaaaaca tcatattctc taataaaaac agagcaaaca ggaaaactgt taaacagaaa
      181 aataaccacc actcccacac cagcgaaact attatcatat cgaaatgcag atttaataaa
      241 agaaaactac attacagaaa aagttttatc tattttcaat ataaaacggg atttcgttgc
      301 tgtaagaatc caaagcaatc agtttactga tttaaaaaac aagacaattc agggtcataa
      361 agacactgtc gcaaaagtca tggactggta taacccacaa aaaaacgcat ttggtatcat
      421 gatgggcaca ccaagacgtt ctgctgatat agcaaaggaa gaatccagaa acgctctaaa
      481 tttcatgata atggaaaagg atacatttaa tgaaaagata cttaacagca atgataattt
      541 acaaaaaaaa tacggcacaa cagaaaatag tagttgggta tcggcttctg ttggttctct
      601 tctggacaaa ggagccaaag tatatccaga tatatcatgc tctctgagac tgggagaacc
      661 attcattatt acacttccag aaacagtcag gctggatgtt gatatccacc cactcaaaaa
      721 atgaacctga acgttttcat gcaggcaaat gcgtccacat caaagcttca accaggtgct
      781 ctcctcctgt cacaggataa atttgtctgt aaaaatcaaa ctctcccaac tcattaccaa
      841 taccaatcag ttgaatgctg ttgccatcta caataaattt ttccgctgac ggaaccaaaa
      901 ttaaggcttc cggatgttca ttaggaaagg tgttagcaag agtacgctga atatccctct
      961 ccagcaaaat ctcctgagta ttagcgtaaa gcgctggcgt aaactcatcg acgaaatcgt
     1021 tactatccct tgggcgcata tgtatcattg aatacgactg ttctccagat tctgataatc
     1081 catggcgaac aataagaaca ctacagccgc tttgctgatt ggttagccat aacggtgaaa
     1141 tttgctggat agtttgagaa atatcatttc gccggaggct tatacactga ttactcaagc
     1201 ttacaactgc aggtgcatca aagcggtccg gactatcagt atcacgcata cctgtaaaca
     1261 gaatataatc actaccagcc atatcatctt ccgtttcttt tagtcttaac aagccatcct
     1321 ctcttgtaat attaactgta attaaagatg tctcatcatg atgggcatag cgctgtggat
     1381 taagaattaa atgctcttcc agaaatttta cagggttact acgtatttca ttcattatac
     1441 accgaagctc tgaacgatgc ggcaccagaa agtgcccggt attttgtgaa ataatactac
     1501 ttaccttgat tgttttctct ccagctcatg aaaaataact cgcgtattat attgttttac
     1561 caaccacagg ccccgaatgc ctgtggtgtt tttatataaa ttatcggaag ttaatattgt
     1621 ttcatttgaa acatcttaac tatcttttat aataaagctt ccccttgcag ggtcatattt
     1681 acactcttct ggtttaacaa tcattgatgg ggttattgga gctcgtgtca gagggtgaac
     1741 tgaaccgtca ttaaccacgc gagaaagtgc atcaacatca aataaagtgc atactgctga
     1801 actatctgaa tttttgacaa ataccccttc ttctggtgtt tccagtataa ttgggcatcg
     1861 agttgcatca gagggacact ggaggctctc tgtattaaca gaaaacttac attgatatat
     1921 tttatcctga ggagtcactt gcgattgtgt ttcacctgca tctgatcctg aaagaatact
     1981 taacattctc tcgccaagag cttgaggccc attattgaac cctaaaagca ataattcagt
     2041 aaataatccc ccagtgccat cgctggccag aaagcgccca tctgttgggc tatattcaat
     2101 tctgacagtt tcaccaccca ttgtaaattc tccacgccca gtggctgcaa cttgagcacg
     2161 aagaacctcc attccaagat ggaacgaaga tgaattaata tctgaggtta atggcataat
     2221 aaagctccct gttttaattt gaactccaga cttaaaggtc cacaacaaat gtcatccaca
     2281 aatttttccc tcgtcccatc agcacaccga atttgcagcg gcctcaccac gcactgtatc
     2341 ggctttttat ccgcacccag tatcaccacc tgcgtgatta ccctgtcctg ctccggaata
     2401 atgccctatt cgcttgttct cagaaattgc cagcaacctt acactacttc ttttgagccc
     2461 atttttcgcc agccctgaat acaggaaagt gttaactgtt tttatgttta ccctcatctc
     2521 actggcgaga tgggacggac gcaactgacg gtagatatat ccaaacatca ccaccatctc
     2581 tgacatcgtc agtgcccgtg cttttttgtt ccaggtccac aatctgttac gcacagcatt
     2641 atgtatatca tgtccccctt tcaacgcttc cagatccagc tgaataaaac ggcgtccctg
     2701 aaacatgctg cgcattaaat ggcccaactg actatcacag attattaacc aggattcttt
     2761 actatccaga ataaccctgc gattttccgg cataaaaaat tcttgagcca gaattacacg
     2821 gcatcctttc agtaacaaac gcaaaccata ttccagataa taattacgcg tcgcaagaat
     2881 gagcttcatc gccctacttc cctgaactac agtagtgttc catgcctcgg tcgcaatcag
     2941 aatttatgat tccccctcca gggaacaaga tggacactcc cctgctcctt aaaggcatcc
     3001 ttcactccat cgtattaaca tgtttattac ttcacactct aataacaaac atcccccata
     3061 catgacaaca aaaaccggag ccggcctccg gttttttgtg aacccgtcgg ctatttcatc
     3121 ccgccaatat tttcccacgt cccgtcagca cgcaggattt gcagcggtct taccacacac
     3181 tgtatctgct ttttatctgc atccagtatc accacctgtg tgattaccct gtcctgctcc
     3241 ggaataatgc cattctcatc tgactccagg atgtctgccg gccccagtcg cagttgtact
     3301 gtaagcgact gcccgtgttc acagtcatca tgctttccgc aaccacacag acgctccata
     3361 agctttctca aaatattcat gtcattctcc tgttctgcct gtatcactgc ccacttcatc
     3421 cagtccctta acatcctgcc acggcccgtc
//
LOCUS       DAZUDJ010000188         3439 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.192, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000188 DAZUDJ010000000
VERSION     DAZUDJ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3439
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.192"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            130..465
                     /gene="eutS"
                     /locus_tag="ACHY1N_005120"
     CDS             130..465
                     /gene="eutS"
                     /locus_tag="ACHY1N_005120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HFS4047246.1"
                     /translation="MDKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIM
                     TLTPGETAMIAGDLALKAADVHIGFLDRFSGALVIYGSVGAVEEALSQTVSGLGRLLN
                     YTLCEMTKS"
     gene            478..957
                     /gene="eutP"
                     /locus_tag="ACHY1N_005121"
     CDS             478..957
                     /gene="eutP"
                     /locus_tag="ACHY1N_005121"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HFS4047247.1"
                     /translation="MKRIAFVGTVGAGKTTLFNALQGNYTLARKTQAVEFNDKGDIDT
                     PGEYFSHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLMDIGVSKRQIAVISKTD
                     MPDADVAATRKLLLETGFEEPIFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE"
     gene            932..1633
                     /gene="eutQ"
                     /locus_tag="ACHY1N_005122"
     CDS             932..1633
                     /gene="eutQ"
                     /locus_tag="ACHY1N_005122"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HFS4047248.1"
                     /translation="MKKLITANDIREAHARGEQAMSVVLRASIITPEAREVADLLGFT
                     ITECDESIPVTASVPASVPADKTESQRIRETIIAQLPEGQFTESLVAQLMEKVMKEKQ
                     SLEQGAMQPSFKSVTGKGGIKVIDGSSVKFGRFDGAEPHCVGLTDLVTGDDGSSMAAG
                     FMQWENAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTTSS
                     VKFLYVAWPANWQSL"
     gene            1630..2433
                     /gene="eutT"
                     /locus_tag="ACHY1N_005123"
     CDS             1630..2433
                     /gene="eutT"
                     /locus_tag="ACHY1N_005123"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006580 - ethanolamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HFS4047249.1"
                     /translation="MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLR
                     IKFIDEQGRLFVDDEQQQPQPVHGLTSSDEHPQACCELCRQPVAKKPDTLTHLSAEKM
                     VAKSDPRLGFRAVLDSTIALAVWLQIELAEPWQPWLADIRSRLGNIMRADALGEPLGC
                     QAIVGLSDEDLHRLSHQPLRYLDHDHLVPEASHGRDAALLNLLRTKVRETETVAAQVF
                     ITRSFEVLRPDILQALNRLSSTVYVMMILSVTKQPLTVKQIQQRLGETQ"
     gene            2430..>3439
                     /gene="pta"
                     /locus_tag="ACHY1N_005124"
     CDS             2430..>3439
                     /gene="pta"
                     /locus_tag="ACHY1N_005124"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFS4047250.1"
                     /translation="MIIERCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPIL
                     VANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEFAHRWLARAGEKTPPDALEKLTD
                     PLMFAAAMVSAGKADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGP
                     PLGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANV
                     QQATEIVRERAPKLVVDGELQFDAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAAVPRQTEVNRESSLQ
                     TLV"
BASE COUNT          807 a          916 c          994 g          722 t
ORIGIN      
        1 tgcaccacag cgaatatctc tccattctta gtgatctacc tcacctttta aacgcgcttg
       61 ccgaattttg ttatttactc tgacgaaaaa ttgtcacgat acacgaaagt ttttcacagg
      121 cggcgactca tggataaaga acgcatcatt caggaatttg tgcccggcaa acaggtcaca
      181 ctggcgcatc tcatcgcgca tcccggtgag gaactggcga agaaaatcgg cgttccggat
      241 gcgggcgcaa ttggcattat gacgctaact cccggcgaaa cggcgatgat cgccggtgat
      301 ttagcgctga aagccgctga tgtgcatatc ggttttctcg accgcttcag cggtgcattg
      361 gtgatttatg gctcggtggg cgcagtagaa gaagcgttat cacaaaccgt cagcggttta
      421 ggtcgcttat taaattatac gctttgtgaa atgaccaaaa gttaatacga ggcattcatg
      481 aaacgaattg cgtttgtggg taccgtcggg gcaggaaaaa caacgttatt taatgcgttg
      541 caggggaatt ataccctcgc cagaaaaaca caggccgtgg aatttaatga taagggcgat
      601 attgatacgc cgggtgaata ttttagccat ccccgctggt atcacgcctt aattaccacg
      661 ctacaggatg tagacatgct gatctatgtc catggcgcaa atgacccgga aagtcggttg
      721 cctgccgggt tgatggatat tggcgtcagc aaacggcaaa tcgccgtcat cagtaaaacg
      781 gacatgccag atgctgacgt cgccgcaacg cgaaagttat tgcttgagac gggtttcgaa
      841 gagccgattt tcgagctaaa cagccacgac ccgcaaagcg tgcagcaact ggtggattat
      901 ctggcatctc tcaccaaaca ggaggaagca ggtgaaaaaa ctcatcacag cgaatgatat
      961 tcgtgaagca cacgcgcgcg gcgaacaggc aatgtccgtg gttctgcgcg ccagcattat
     1021 taccccggaa gcccgtgaag tggcggatct actgggtttt accatcaccg aatgtgatga
     1081 atcgatcccg gtaacggcgt ccgtgcccgc cagcgtgcca gccgacaaaa ccgaaagcca
     1141 gcgcatccgc gaaaccatca ttgcccagct gccggaaggc cagtttaccg aaagcctggt
     1201 cgcacagctg atggaaaaag tgatgaagga aaaacagtcg ctggagcagg gcgcaatgca
     1261 gccgagcttc aaatcggtga ccggcaaagg cggcatcaaa gtgattgatg gcagcagcgt
     1321 caagtttggt cgtttcgacg gcgcagagcc gcattgcgtg ggcttgactg atcttgtgac
     1381 cggagacgac ggcagcagca tggccgctgg ttttatgcag tgggagaacg cattcttccc
     1441 gtggaccctg aactacgacg aaatcgacat ggtgctggaa ggggagctgc atgttcgcca
     1501 cgaaggcgaa accatgatcg ccaaagcggg tgacgtgatg tttatcccga aaggctccag
     1561 tatcgaattt ggtacgacat ccagcgtgaa attcctgtat gtcgcctggc cggctaactg
     1621 gcaatcccta tgaaagattt catcaccgaa gcatggctaa gagcgaacca tacgctcagc
     1681 gaaggcgcag agatccatct ccctgcggac agtcgcctga cgccctctgc ccgggagtta
     1741 ctggaaagcc gccatctgcg catcaagttt attgacgagc agggccgcct gtttgttgac
     1801 gatgaacagc agcagccgca gcccgttcat gggctgacca gtagcgatga acatccgcag
     1861 gcgtgctgcg aactgtgccg ccagccggtg gcaaaaaagc cggatacgct gactcacctg
     1921 tcggcggaaa aaatggtcgc caaaagcgat ccgcgtctgg gttttcgcgc ggttctcgac
     1981 agcaccattg cgctggcagt gtggctgcaa attgaactgg cggaaccgtg gcagccgtgg
     2041 ctggcggata tccgttcgcg tcttggcaac attatgcgcg ccgatgcgct gggtgaaccg
     2101 ctgggctgcc aggcgattgt cgggctttct gacgaagatc tgcatcgact ttctcaccag
     2161 ccgctgcgct atctcgacca cgatcatctg gtgccggaag ccagccacgg gcgcgatgcg
     2221 gcgttgctca atctgctacg taccaaagtg cgggaaaccg aaaccgtagc ggcgcaggtg
     2281 tttatcaccc gcagctttga agtattacgc ccggacattt tgcaggcgct gaaccgcctt
     2341 tccagcacgg tctacgtgat gatgatcctg agcgtaacga agcagccgct aacggtgaag
     2401 cagatccaac aacgactggg ggaaacgcaa tgattattga acgttgtcgt gaactggcgt
     2461 tgcgagcgcc cgccagagtg gtttttccgg atgcgttaga ccaacgtgtg ctgaaagccg
     2521 cgcaatattt acatcaacaa ggtctggcaa cgcccattct ggtcgccaat ccgtttgaac
     2581 ttcgtcagtt tgcgctcagt cacggcgtgg cgatggacgg gctacaggtg attgatccgc
     2641 atggcaacct cgcaatgcgg gaagaatttg ctcatcgctg gctggcccgc gcgggcgaaa
     2701 aaacgccgcc ggatgcgctg gaaaaactta ccgaccctct gatgttcgcc gcagcaatgg
     2761 tcagcgccgg taaagcggat gtctgtatcg cgggcaacct ctcttccacg gcaaatgtgc
     2821 tgcgtgccgg attacgcatt atcggcttgc agccaggctg taaaacgctc tcttccattt
     2881 tcctgatgtt gccacagtac agcggcccgc cgttgggctt tgccgattgc agcgtggtgc
     2941 cacagccgac ggcggcgcag ctggcggata tcgcgcttgc cagtgccgaa acctggcgcg
     3001 ccatcaccgg agaagagccg cgcgtggcga tgctgtcgtt ttccagcaat ggtagcgccc
     3061 gtcacccctg tgttgctaac gtccagcagg cgacagaaat cgtccgtgag cgcgcaccaa
     3121 agctggtggt ggatggcgag ttacagtttg acgccgcctt cgtgccggaa gtggcggcgc
     3181 aaaaagcgcc tgccagcccg ctacagggca aggccaatgt gatggttttt ccgtcgctgg
     3241 aagccggaaa tattggttac aaaatcgcac aacgactcgg cggatatcgt gccgtcgggc
     3301 cactgataca aggacttgcc gcgccgatgc acgatctctc tcgtggttgt agcgtgcagg
     3361 aaattatcga gctggcgctg gtggcagctg tgccgcgtca gacagaagtg aaccgcgaaa
     3421 gcagtttaca aacactggt
//
LOCUS       DAZUDJ010000189         3382 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.193, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000189 DAZUDJ010000000
VERSION     DAZUDJ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3382
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.193"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..198)
                     /locus_tag="ACHY1N_005125"
     CDS             complement(<1..198)
                     /locus_tag="ACHY1N_005125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858330.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047251.1"
                     /translation="MKYDGDGRATARFFSGKGCRRAPLFTAPADAARHKRCLWSVSRV
                     RRARDGRFYRSRLASVTVYASP"
     gene            complement(195..1097)
                     /locus_tag="ACHY1N_005126"
     CDS             complement(195..1097)
                     /locus_tag="ACHY1N_005126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HFS4047252.1"
                     /translation="MHFSGEPAQIAEIKRLASGAVTPLYRRATNEGIQLFLAGSAGLL
                     QTTEDVRFEPCPGLTAAGRGVVSPENIAFTRWLTYLQNGVLLDEQNCLMLHELWLQSG
                     TGQRRWEGLPDDVRDTITALFTAKRGDWCGFWSNEDVSVWWNRLCDNVLPEKTMPFDL
                     LTVLPTRLDVEVNGFNGGVLNGVPSAYHWYTEQYGVKWPVGYEVNISSQGDNFIQVDF
                     DTPWYQPESDVIAELSRRFSCTLEHWYAEQGCNFCGWQRYERGELVDVLWGELEWSHP
                     TDDDELPEVTGPAWIVDKVAHYGG"
     gene            1370..2329
                     /locus_tag="ACHY1N_005127"
     CDS             1370..2329
                     /locus_tag="ACHY1N_005127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HFS4047253.1"
                     /translation="MLKVSCDDGSTNVKLAWLEDGEVRTSLSGNSFKEGWNPGLFNAG
                     KVYNYVVDGKKYTYDLGSTAVIGTTHVSYQYSTTNLLAIHHALLTSGLQPQDVELTVT
                     LPVTEFFDNDNQPNEERIERKKANVLREISLNKGETFKIKKVNVMPESLPAAFESLKK
                     DKVNKLERSLIIDLGGTTLDCGLILGAFEGISEIRGYSEIGTSRITHTVMNALTKAST
                     PCNYFIADELIKNRHDNEYLQTLINDVAEIKNITHVIDREVKSLAESIRQEISTFSGM
                     NRIYLTGGGAELIYPHIKQYFPNLKVNKVDEPQFALVKAMVHA"
     gene            2329..2724
                     /locus_tag="ACHY1N_005128"
     CDS             2329..2724
                     /locus_tag="ACHY1N_005128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HFS4047254.1"
                     /translation="MESSDPKKRKKVVAYLHPTLYPQDNLTQQTIDSLPIQMRGDFYR
                     QSLICGAALYSVDPRLLTLISGFFSEKITAENLVKLIEQTTGYTSTSIDISVLKNIIG
                     ASSENKSESITSKDDFEEQTRRNLSMLKK"
     gene            complement(2804..3382)
                     /locus_tag="ACHY1N_005129"
                     /pseudo
     CDS             complement(2804..3382)
                     /locus_tag="ACHY1N_005129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     misc_feature    complement(3181..3291)
                     /locus_tag="ACHY1N_005129"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /pseudo
                     /db_xref="RFAM:RF01497"
BASE COUNT         1001 a          859 c          751 g          771 t
ORIGIN      
        1 cgggctggcg tacactgtca ccgacgccag ccgggagcgg taaaagcgcc cgtcccgtgc
       61 ccgccggacg cgggacactg accacagaca gcgtttatgc cgcgccgcgt cagccggcgc
      121 agtaaaaaga ggagcacggc gacatccttt accggaaaag aaacgggcag ttgcccgccc
      181 gtctccgtca tacttcatcc gccataatgc gccaccttgt cgactatcca cgcaggtccg
      241 gtgacttccg gcaactcgtc atcatctgtc ggatgtgacc attccagctc cccccacagc
      301 acatcaacaa gctcgccacg ctcatatcgc tgccagccac agaaattgca gccctgttcg
      361 gcataccagt gctccagtgt gcagctgaaa cggcggctta attctgcaat aacgtcgctt
      421 tccggctgat accacggcgt gtcgaaatca acctgaatga agttgtctcc ctgactactg
      481 atattcacct cataccccac aggccacttc acgccatact gttccgtata ccagtgatat
      541 gcagaaggaa caccgttcag aacaccaccg ttaaagccat tcacttcaac atccaggcgg
      601 gtcggcagaa ccgtcagcag gtcaaacggc atggtttttt ccggcagtac gttgtcacac
      661 agacggttcc accacaccga tacatcctcg ttactccaga agccacacca gtcacctctt
      721 tttgcggtga aaagtgcggt gatggtatcc ctgacatcgt ccggtaatcc ttcccagcga
      781 cgctgtccag taccgctctg cagccagagt tcatgcagca tcaggcagtt ttgctcatcc
      841 agcagtacac cgttctgcag gtatgtcagc cagcgggtga acgcgatatt ctccggcgat
      901 acaacgccac gcccggcagc cgtcagtccg gggcatggtt caaaccgcac atcttcagtg
      961 gtctgcagaa gtccggcact tccggccaga aacagctgaa taccttcatt tgtggcgcgg
     1021 cgataaagcg gtgtgacggc accgctggcc agtcgtttaa tctcagcaat ctgtgccggt
     1081 tcaccagaaa aatgcatacg atttgagcac cagtttggca tgggaattct cctctcacat
     1141 gcggcctggt taagtagttt ccgtctcagt tcgaaacgca aaatgagaaa tcgatagaga
     1201 ctcaaactga gtcacaacaa gaatgcaaag agactctaaa agagcctcat cgcttgacat
     1261 gaacccaaaa tgagacacaa taaggaacaa caaaaaactc aaaaagatgc atctagataa
     1321 aggatgctca atttgagata aataaaaact caaaacgagg caagaaaaaa tgctaaaagt
     1381 atcatgcgat gatggttcaa ctaacgtaaa actggcctgg cttgaagatg gcgaggtaag
     1441 aaccagtctg tcaggaaaca gctttaaaga aggctggaac ccgggactgt ttaatgccgg
     1501 caaagtttac aattacgtcg tggatggaaa aaaatacacc tatgatttgg gcagtactgc
     1561 tgtcataggt acaacacatg tcagttatca atacagcacc accaatttgc ttgccataca
     1621 tcatgcactg ctgacatccg gccttcagcc acaggatgta gaactgacag tgacattacc
     1681 tgtaaccgaa ttctttgata atgacaatca accaaatgaa gaaagaatag aaagaaaaaa
     1741 ggcaaatgtt ctccgtgaga tatctctgaa taaaggggaa acatttaaaa ttaaaaaagt
     1801 taatgtaatg cctgaatctt tgccagctgc atttgaatca ctaaaaaaag ataaagtaaa
     1861 caaacttgaa cgcagcctga ttatcgatct tggaggaacc actctggatt gtggtttaat
     1921 tctcggtgca tttgaaggca tttctgaaat ccgtgggtat tcagaaatcg ggacatcccg
     1981 catcactcat accgtcatga atgcgctgac gaaagcctcc acaccatgta attattttat
     2041 tgctgatgag ttaataaaaa acagacatga taatgaatat ctccagacat taataaatga
     2101 tgtagctgaa ataaaaaaca ttactcatgt aatagacagg gaagtgaaat ctctggcaga
     2161 aagcatcagg caggaaattt caacattctc aggaatgaac cgaatctatc tcactggcgg
     2221 aggagccgag cttatttacc ctcacataaa gcaatatttc ccgaatctga aagtgaacaa
     2281 ggtggatgaa cctcagtttg cattggtgaa agcaatggtg catgcgtaat ggaaagcagt
     2341 gatccgaaaa aaagaaagaa agttgtggca tacctgcacc cgacacttta tccgcaggat
     2401 aacctgacac aacaaacaat agactctctc ccgatacaaa tgcggggaga cttctacaga
     2461 caatctctta tttgcggagc agctctttat tctgttgacc cccgactgtt aacgctaatc
     2521 agtggttttt tcagtgagaa aatcactgca gaaaatctgg tgaaacttat agagcaaaca
     2581 acaggataca catctacatc aattgatata agtgtgttaa aaaacatcat aggggcatct
     2641 tcagaaaaca aatcagagag catcacttca aaagatgatt tcgaagaaca aaccagacgc
     2701 aatctttcta tgttaaaaaa ataataaaag aagagcaggt taagtctatt acctgctctt
     2761 cttttattat gagggaccag cagcggtttt agtgccctaa atcgaacgcc atacagacga
     2821 agccctgcca tgtgctgacg taagtaaaat ccgccaccca cagctggtca ggacgttctg
     2881 ccacgaactg gcggtttacg ctgtcgcctg cggcaacagc tttccggctg acggtagtgc
     2941 ggaccttttt accccggaga acaccggcaa gtcccataac cgccatgagg cgcgccacta
     3001 tacatctggc caccctgata ccttcctgta acaactgacg tcagacttta cgccaccgta
     3061 tacctgatga ttctcatcgt ataagcgcag tatctctttc ttcagccagt catcgcgctg
     3121 tgcacaggca ctacgtttat aaggatgata ccgctgttgc tgacagtggt aatacgttga
     3181 cggggcaata tgcagttcac tgcataccgg tccgaccccg tactgctcac gcagcagcag
     3241 tggcattatt ttttccagag gcggtcgaac tcggccttcg caaaataagc ggaagcctgg
     3301 cgaaggatat cgttactgcg gcgcagttca cggttttcac gttccagctc tttcagacgc
     3361 tgacgttcag cgctggtgag cc
//
LOCUS       DAZUDJ010000190         3316 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.194, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000190 DAZUDJ010000000
VERSION     DAZUDJ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3316
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.194"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..438
                     /locus_tag="ACHY1N_005130"
     CDS             <1..438
                     /locus_tag="ACHY1N_005130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309145.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HFS4047255.1"
                     /translation="LGEGTIIHIVPRLAGAGKGGLQIVLGAAAIVGSFFTAGATMALW
                     GSALAAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTYFSSLDNM
                     IAQGNPMPVPYGEMLVGSRRISQDISTRDEGGDGKVVVIGRQA"
     gene            complement(629..1156)
                     /gene="sodC"
                     /locus_tag="ACHY1N_005131"
     CDS             complement(629..1156)
                     /gene="sodC"
                     /locus_tag="ACHY1N_005131"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC"
                     /protein_id="HFS4047256.1"
                     /translation="MKCKIIAAIAMLTAASCGYAAEQEVPMNLVSADGKEVSIGKITI
                     QETPYGLLFTPALHSLSEGIHGFHVHEKGNCAPALKDGKPVAALSAGGHFDPKNTGKH
                     LGPWSPDGHLGDLPALFVTHDGKANYPVLAPRLNSLKEIKGRSLMLHAGGDNHHDHPE
                     PLGGGGARMACGIIQ"
     gene            1290..>3316
                     /locus_tag="ACHY1N_005132"
     CDS             1290..>3316
                     /locus_tag="ACHY1N_005132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HFS4047257.1"
                     /translation="MGKGGGRAHTPREAKDNLKSTQMMSVIDAIGEGPIEGPVKGLQS
                     ILVNKTPLMDTDGNPVIHGVTAVWRAGEQEQTPPEGFESSGAETGLGVEVTKAKPVTR
                     TITSANIDRLRVTFGVQSLVETTSKGDRNPTSVRLLIQLQRNGNWVTEKDVTINGKTT
                     SQYLASVILENLPERPFNIRMVRETADSTPDQLQNKTLWSSYTEIIDVKQCYPNTAIV
                     GLQVDAEQFGGQQMTVNYHIRGRIIQVPSNYDPEKRTYSGIWDGSLKPAYSNNPAWCL
                     WDMLTHPRYGMGKRLVAADVDKWALYAIGQYCDQTVPDGFGGTEPRMTFNAYLSQQRK
                     AWDVLSDFCSAMRCMPVWSGQTLTFVQDRPSDVVWPYTNSDVVVDDNGVGFRYSFSAL
                     KDRHTAVEVNYTDPQNGWQTSTELVEDPEAILRYGRNLLKMDAFGCTSRGQAHRAGLW
                     VIKTGLLETQTVDFTLGSQGLRHTPGDIIEICDNDYAGTLTGGRVLSIDAASRTLTLD
                     REVTLPETGAATVNLINGSGKPVSVDITAHPAPDRIQVSTLPDGVETYGVWGLSLQSL
                     RRRLFRCVSIRENTDGTFAITAVQHVPEKEAIVDNGASFEPQSGTLNSVIPPAVQHLT
                     VEVSAADGQYLAQAKWDTPRVVKGVRFSLRLTSGSGEDSRLVTTAITADTE"
BASE COUNT          749 a          875 c         1032 g          660 t
ORIGIN      
        1 ctgggtgagg gaacgatcat ccacattgtg ccgcgactgg ccggggccgg aaagggtgga
       61 ctgcagattg tgctgggggc ggcagccatc gtgggctctt tcttcaccgc cggcgcaacg
      121 atggcgttat ggggttcagc cctggcagcc ggtggttttt ctgccaccac gatgctgttt
      181 tcacttggag ccagcatgat actgggtggt gtggctcaga tgcttgcccc gaaggcaaaa
      241 acaccggatt accgcgcaac ggataacggc agacagaaca cgtatttttc ctcactggac
      301 aacatgattg ctcaggggaa cccgatgccg gtgccttacg gtgaaatgct ggttggctca
      361 cggcgaatct cccaggacat cagtacccgt gatgaaggcg gtgacgggaa ggtggtggtt
      421 atcgggcggc aggcataaaa gcgaaaaaat cccgcagtgc tcacggacag gaactgcggg
      481 agcgttacga agattgagtg taaggaatta ttcttatgtc acgacaaaaa cattaactca
      541 gagagggagg atgtgccgtt cttttcaggg agaaaggatt tatcgtcctg aggaataaag
      601 gtaaggggcc cgccccttac ctgactgatt attgaatgat gccgcaggcc attctcgcac
      661 caccaccgcc caggggctcc ggatggtcat gatggttatc accgccagca tgaagcatga
      721 gagaacgccc tttaatctct tttaatgagt tcagtctcgg ggccaggacc gggtagttcg
      781 cttttccgtc atgcgtcacg aacagcgcag ggaggtcgcc caggtgtcca tccggagacc
      841 aggggccaag atgtttgccg gtgtttttcg ggtcaaagtg accgccagcc gataatgctg
      901 cgaccggttt tccgtctttc agtgccgggg cgcaatttcc tttttcgtgc acatgaaaac
      961 catgaatgcc ttcagacaga gagtgaaggg ctggtgtgaa cagcagaccg tagggggtct
     1021 cctgaatggt tatttttcca atgctgactt cttttccgtc agcactgaca aggttcattg
     1081 ggacttcctg ttctgctgcg tatccgcatg atgctgctgt cagcatggca atggcagcaa
     1141 tgattttaca tttcataaaa ccctcattaa ttccgttaac agactgagct tgctggttac
     1201 agggtaacaa acagcgttct gatgatatcg cgcaatagct gtgcaatatc ctatcactgc
     1261 gattaataat accaattgag aggaacatta tgggcaaagg tggcggcagg gcgcacacgc
     1321 ctcgagaggc gaaggataat ctcaaatcca cgcagatgat gagtgtgatt gatgcgattg
     1381 gtgagggacc gatagaaggc ccggtgaagg ggctgcagag tatcctggtg aacaaaaccc
     1441 cgctgatgga cacggacggt aatcccgtga tacacggtgt gactgcggtc tggcgtgccg
     1501 gggagcagga gcagacacca ccggaaggct ttgagtcctc cggagctgaa accggactgg
     1561 gcgtggaagt gacgaaggca aagccggtga cgcgcaccat tacgtccgcg aacattgacc
     1621 gcctgcgggt taccttcggg gtgcagtcac tggtggagac cacctcaaag ggtgaccgta
     1681 acccgacgtc tgtccgcctg ctgattcagt tgcagcgtaa cggtaactgg gtgacggaaa
     1741 aggatgtcac cattaacggc aagaccacct cacagtacct ggcgtcggtg attctggaga
     1801 atctgcctga gcggcccttt aacatccgga tggtccggga gacagcggac agcaccccgg
     1861 accagctgca gaataagacg ctctggtcgt catacaccga aatcatcgat gtgaaacagt
     1921 gctacccgaa cacggcgatt gtggggctgc aggtggatgc ggagcagttt ggcggtcagc
     1981 agatgacggt gaactaccat atccgcggtc gcatcatcca ggtaccgtca aactatgacc
     2041 cggaaaaacg cacgtacagc ggcatctggg acggcagcct gaaaccggca tacagcaaca
     2101 acccggcctg gtgcctgtgg gacatgctga ctcacccgcg ctatggcatg ggaaaacgtc
     2161 tggtggcggc ggatgttgac aagtgggcgc tgtatgccat cgggcagtac tgcgaccaga
     2221 cggtcccgga tggtttcggg ggcacagagc cgcggatgac ctttaatgcg tacctgtcac
     2281 aacagcgtaa ggcgtgggac gttctcagtg atttctgctc ggcgatgcgc tgtatgccgg
     2341 tatggagcgg ccagacgctg acgttcgttc aggaccgccc gtcggatgtg gtgtggccgt
     2401 acaccaacag cgatgtggtg gtggatgata acggcgtggg attccgctac agcttcagtg
     2461 ccctgaagga ccggcacacg gcggtggagg tgaattacac cgacccgcag aacggctggc
     2521 agacctccac tgaactggtg gaagacccgg aagccatact gcgctacgga cgcaacctgc
     2581 tgaagatgga cgcgttcggc tgtaccagcc gcggtcaggc ccaccgtgcc ggactgtggg
     2641 tgataaagac cggactgctg gaaacgcaga cggtggattt cacgctcggg tctcaggggc
     2701 tgcggcacac acccggtgac atcattgaaa tctgtgataa cgactatgcc gggaccctga
     2761 ccggcggacg tgtcctgtcc attgatgccg ccagccgcac cctgacactg gaccgtgagg
     2821 tgaccctgcc ggagacaggt gccgccacgg tgaacctgat taacggcagc ggtaagccgg
     2881 tgagtgtgga catcaccgca caccccgcgc cggaccggat acaggtcagc accctgcctg
     2941 atggtgtgga gacatacggt gtatggggac tctccctgca gtcactgcgt cgtcgcctgt
     3001 tccgctgtgt ctccatccgg gaaaacacgg acggcacctt tgccatcacg gcggtgcagc
     3061 acgtaccgga aaaggaagcc atcgtggata acggggccag ctttgagccg cagtcaggca
     3121 ccctgaacag cgtcatccct ccggcagtgc agcacctgac ggtggaggtg agcgcagctg
     3181 acggtcagta tctggcacag gcgaaatggg acacgccgcg ggtggtgaag ggtgtgcgct
     3241 tcagtctgcg cctgaccagc ggaagcggag aagacagccg tctggtgacc accgccatca
     3301 ctgcggatac agagca
//
LOCUS       DAZUDJ010000191         3311 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.195, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000191 DAZUDJ010000000
VERSION     DAZUDJ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3311
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.195"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..291
                     /locus_tag="ACHY1N_005133"
     CDS             <1..291
                     /locus_tag="ACHY1N_005133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012907691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HFS4047258.1"
                     /translation="ISFYLKPAAVKNEGEACAWLDSLTPEARKSGQRVAFLAGLALLK
                     MNPAEAYRLAAWADDEALSVTQTRTERPASQPVSTAQITSQMAGNIRALFPE"
     gene            355..725
                     /locus_tag="ACHY1N_005134"
                     /pseudo
     CDS             355..725
                     /locus_tag="ACHY1N_005134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289969.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ead/Ea22-like family protein"
     gene            complement(828..1358)
                     /locus_tag="ACHY1N_005135"
     CDS             complement(828..1358)
                     /locus_tag="ACHY1N_005135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001412162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047259.1"
                     /translation="MKKDSYPYLICMTVSVLGIIFLFYWWRADIYRITYLNSRISNYY
                     ILCSMGMSFFFSLFLVKRGVVKQSGWKGLSEYLKVYAGSCILTGIFLIIPLMMVTYFL
                     PGVTSSYVAPYEYTSGSSRSCSGAFVDDPELHKNILICYPYGNYEYDNIIYVEKKTNA
                     LGVVVTYAQTARDDAE"
     gene            complement(1889..2935)
                     /locus_tag="ACHY1N_005136"
     CDS             complement(1889..2935)
                     /locus_tag="ACHY1N_005136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001706445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4047260.1"
                     /translation="MSRKNKKVRMSSRIDLADALRKESSLSAFTFDGPYRLTGHDLLD
                     NMYCADNGRWYETPVDWYGLARAARQTSWHQSALYFKRNVLLGCYIPHPLLSRQDFSA
                     LALDWFVFGNAFLELRSNMLGEPLKLRHALAKYMRRGSDLESWWYVQDGKDAFQFRPG
                     KVCHLMNPDINQEIYGMPEYLGALLSASLSHSADMFRKLYYDNGSHAGCIIYIGAAQV
                     NRESMDSLKETLQGARGGGAFKNVLIHAPNGGKEGVQILPFQQITAKDEFMNVKAASR
                     DDVLAAHRVPPQLMGAMPGEKSAFGDVEKAARVYAINELMPVMEAMKHINDWLGEEVI
                     RFNPYALLDTQPTS"
     gene            complement(2935..>3311)
                     /locus_tag="ACHY1N_005137"
     CDS             complement(2935..>3311)
                     /locus_tag="ACHY1N_005137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047261.1"
                     /translation="RYNVEHIGIDVTGGNGEAVYQIVKRFFPAAIPYTFTLSSKRSLV
                     LKMLQIMRAGRWEYDRAERELVAAFNAVRKVKTPGGFITYETDRARGISHGDLAWATM
                     LAVINEPIGGEGENERFTVMEF"
BASE COUNT          891 a          854 c          786 g          780 t
ORIGIN      
        1 ataagtttct atctgaagcc cgccgccgtc aagaacgaag gcgaagcatg cgcctggctg
       61 gacagcctta caccagaagc ccgcaaaagc ggccaacgtg tggcttttct ggccgggctg
      121 gcacttctga aaatgaatcc ggcagaggct taccgactgg ctgcatgggc tgatgatgaa
      181 gcgttatcag tgacacaaac caggacagaa cgccccgcat cacagccagt atcaaccgca
      241 cagataacca gtcagatggc cggaaatatc cgggcgttat ttcctgaata acacaacatc
      301 agggcgagtt cgccctgctc tccacctcag aacataaaca aggagaacga cttaatgagc
      361 gaaatcaact atcaggcatt acgtgaacgt tattcacctg tgccagtacc gaaatgccct
      421 atttgcggcg aggaaatgtc aattcagcga atatctggag cacaggttgt ttatgcctgc
      481 tccggttatg gtgatgatgg agatttcaaa attggccgaa ctcttgccga cgaacattat
      541 gaaaaatcac acgtaacagt gttggatgtc gggatcctga agtattggcg ctacttgatt
      601 ggctggaaac caaagacaac cgaatcgctg aactggaaaa aatcgccact gactatgcac
      661 ttaaattcca gaaagcacag gacgcattaa agtacgccgc tttgctgcat agcaggacag
      721 cgcagctaaa atactaactt aaagcggaag attaatacat ggtgagtcgg ggtaatttgt
      781 ttttatccca acaaataaac aaaaaagtgg actatctctg tagtatctta ttcagcatcg
      841 tctcgtgcag tctgtgcata cgtcacaaca acgcccaatg cattagtttt cttttcaaca
      901 tagataatat tgtcatattc atagttacca tacggatagc aaataagaat atttttatgc
      961 agttcgggat catcaacaaa cgctccggaa cagcttcttg aactaccaga tgtatactca
     1021 tacggtgcaa catatgatga tgttactcct ggtaaaaaat aagtcaccat cataagaggg
     1081 ataatcagga atatccctgt aagaatgcaa gagccagcat aaaccttcag gtattccgac
     1141 agtcctttcc agccactttg cttcactacc cccctcttca ccagaaacaa ggagaagaaa
     1201 aaggacatac ccatactaca caagatgtaa taattggata tacgcgaatt aagatatgta
     1261 atcctgtaga tatctgccct ccaccagtaa aagaggaaaa taatccctag cactgaaaca
     1321 gtcatgcaaa tcaaataagg atatgaatct ttcttcatgt cttgcgccca ttaaaatttc
     1381 cctgctacga acaaatttac catccgtttt ttgcgcagaa aacagcacga tgcacactgc
     1441 acgatagtgc acaaatttgc acaatttttt tgaacgactt tttgcccttc cggcccccgt
     1501 ggcggctgga tccgtcaagg atccgtgcgt gcacaaaaaa acgcgttttt tctgcgcgca
     1561 ggtgacgggg gaacagcccg cgtttcaggg ggtaaatagc attccctgaa cgatgtcgca
     1621 gagatacaac agaatggctg tatttctcac gctgagcgtg aaaaagacgt gagggctttt
     1681 gatttgatgg ggtgaaaggt aaggccgtca aaatcgcact gagacggcga gaacatgcag
     1741 tcaacgcggt gggattgcgt aagagtctga ctgtcgatga tggcaatcag caggaaagcg
     1801 tcgtgaaatt atctgactga tacaggagct ggagagtcgg ggcataaatt ttttatgccc
     1861 cggcgaagca gcagacaagc gaagcgcgtc aggatgtggg ctgggtgtct aacagtgcgt
     1921 aagggttaaa gcggatcacc tcttccccaa gccagtcatt gatgtgcttc atggcctcca
     1981 tgacgggcat cagctcgtta attgcgtaaa cccgcgcggc cttctccaca tcaccaaacg
     2041 cacttttttc gcccggcatc gcccccatca gttgcggcgg aacgcggtgc gcagccagca
     2101 catcatcacg ggatgccgcc ttaacattca tgaactcatc ctttgcggtg atctgctgga
     2161 acggcaaaat ttgcaccccc tctttgcccc cgttgggcgc atggatgagc acgtttttaa
     2221 acgcgccacc accacgcgca ccctgtaacg tttctttcag ggagtccatg ctttcgcggt
     2281 ttacctgcgc tgcaccgatg tagatgatgc acccggcgtg ggatccattg tcgtaataca
     2341 gttttctgaa catgtccgcc gaatgagaca ggctggccga gagtaatgcg ccaagatatt
     2401 ccggcatgcc gtaaatttcc tggttaatat ccggattcat taggtggcac actttgccag
     2461 ggcgaaactg gaacgcgtcc ttgccatcct gcacatacca ccatgattca agatcgcttc
     2521 cgcgtcgcat gtatttcgcc agtgcgtgcc gtaatttaag cggttcgccg agcatattgc
     2581 ttctaagctc aaggaatgcg ttaccgaaca caaaccagtc cagcgccagc gccgagaaat
     2641 cctgccggga aagcagcggg tgcgggatgt agcaaccgag taatacattg cgcttaaagt
     2701 aaagcgcaga ctgatgccag gacgtttgcc gggctgctct tgccagaccg taccagtcca
     2761 ccggggtttc ataccaccgc ccgttatcag cacagtacat attgtccagc aggtcatgcc
     2821 cggtcaggcg ataaggacca tcaaatgtga atgcactgag cgatgattct ttcctgagcg
     2881 catcagcgag atcaatgcgt gaactcatgc gcactttttt attttttctg ctcatcagaa
     2941 ctccataacc gtgaaacgct cgttttctcc ttcgccgcca atcggttcgt taatgacagc
     3001 aagcatggtt gcccacgcaa ggtcgccgtg gctgatcccc ctcgcgcggt ccgtttcgta
     3061 agtgataaag ccgcccggtg ttttcacctt acgcacggcg ttaaaggccg cgaccagctc
     3121 gcgttcggcg cgatcgtatt cccaccgtcc ggcacgcatt atttgcagca ttttcagtac
     3181 cagcgaccgt ttggatgaca gcgtgaaggt gtacggaata gcagcaggga aaaaccgctt
     3241 cactatctga taaacagcct ccccgttccc gcccgtcaca tcaatgccga tgtgttccac
     3301 gttgtagcga c
//
LOCUS       DAZUDJ010000192         3287 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.196, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000192 DAZUDJ010000000
VERSION     DAZUDJ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3287
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.196"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..701)
                     /locus_tag="ACHY1N_005138"
     CDS             complement(<1..701)
                     /locus_tag="ACHY1N_005138"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFS4047262.1"
                     /translation="MTLKRACSLLTVKSFSEDERVITGIASTPSPDRDGDILEPEGAE
                     FGSTIPFLWQHDHSRPVGQCTVRRVREGLEITAMLVKPVPDMPSQLAARLDEVWAAIK
                     TGLVRGLSVGFRPHEYTYLDGGGLHFLRWELMEVSAVTVPANAECTIRTIKSYDHPFS
                     AASGNRKPVVKIASSAGAAAQSTTVFHKEKTIMNIGEQIKSFENKRAALAASLEEVMT
                     KAAEEGRTLDVEEEE"
     gene            complement(765..2426)
                     /locus_tag="ACHY1N_005139"
     CDS             complement(765..2426)
                     /locus_tag="ACHY1N_005139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HFS4047263.1"
                     /translation="MIPVWSTACPDWAERLKKGLSIIPAPVYPDQAAHALAIFKQLRI
                     VDAPGSPTFGESCAPWVFDLVAALFGSYDAQTGVRHIKEVFILIPKKNSKSTLAAGIM
                     MTALLLNWRQAAGYTILAPTVEVAANAFNPARDMVRRDDDLDDLCQVQTHIRTITHRV
                     TDTTLKVVAADPNTVSGIKSVGTLIDELWLFGKQYKAEDMLREAIGGLASRPEGFVVY
                     TTTQSNEPPAGVFRQKLQYARDVRDGKIHDPHFLPVIFEHPPEMVESGAHLLMENLAM
                     VNPNLGYSVDEAFLYREYRKAREAGEETFRGFMSKHANVEIGLALRSDRWAGADFWEE
                     QGRCISLDDILLRADVVTVGIDGGGLDDLLGMYVIGRDRETREWLGWGHAWAHETAVV
                     RRKSEASRFQDFVACGDMTIVRRVGDDTAEVAEYVRRIHEAELLDHIGIDPSGVGQIL
                     DSLAEAGIPEGIVVGISQGWKLGGAIKTTERKLAEGVLIHGDQPLMAWCVGNARVEPK
                     GNAILITKQASGRGKIDPLMALFNAVSLMSLNPEPKKKAYEVFFI"
     gene            complement(2423..2986)
                     /locus_tag="ACHY1N_005140"
     CDS             complement(2423..2986)
                     /locus_tag="ACHY1N_005140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HFS4047264.1"
                     /translation="MLTTQKRKFALALMSGKNKTASAIAAGYSAKTARVKGSQLAKDP
                     EVLAFIARKQCETVELDEVPVYRQKKMQTEECHKEAPPAEKNSPVSLPPDDGQNLSPL
                     PGIDYMEDGLPDPVKAMGRILVENLIIDPKLALDAAWRLAQFTHHKKGDTGKKSAKGD
                     AAKKAANRFAVPPPPRLVVNNDNEGNG"
BASE COUNT          689 a         1029 c          816 g          753 t
ORIGIN      
        1 tgctcttcct cctccacatc cagcgtgcgc ccttcctctg cggctttggt catgacctcc
       61 tcaagggagg ctgccagcgc tgcacgcttg ttttcaaaac ttttaatctg ttcgccaata
      121 ttcattatgg tcttttcctt atgaaaaacg gttgttgact gtgccgcagc gccggcagaa
      181 gatgcgattt tcaccaccgg tttccggttg ccggacgcgg cagaaaacgg gtggtcgtaa
      241 gatttaatgg tccggatggt gcattccgca ttcgcgggca cggtgacggc agacacctcc
      301 atcagttccc agcgcagaaa atgcagtccg cctccgtcca gataagtgta ttcatgggga
      361 cggaagccca cggacagccc cctgaccagc ccggtcttaa tggccgccca gacctcatcc
      421 agccgggcag ccagttgcga cggcatatcc ggtacgggct tcaccagcat tgccgtgatt
      481 tccagccctt ccctgacccg acgcaccgta cactggccta cagggcggga atggtcatgc
      541 tgccagagaa acgggatcgt actgccaaac tccgccccct ccggctccag gatgtcacca
      601 tcccgatccg gagaaggcgt tgacgcaatc ccggtgatca cccgttcatc ctcactgaag
      661 gatttcaccg tcagcaggga acaggcccgt ttaagagtca catcagcctc ctgaaaataa
      721 aaaaaccgcc gcagcggttc atgatggtta cagggtgagc agggttatat gaaaaaaacc
      781 tcatacgctt tctttttcgg ttccggattc agggacatca gggagaccgc attgaacagc
      841 gccatcagcg ggtcaatttt tccccgtccg ctggcctgtt tggtgataag aatggcgtta
      901 cctttaggct ccacccgggc attgccgaca caccaggcca tcaggggctg gtcaccgtga
      961 atcagcaccc cttcagccag tttgcgctcg gtggttttga tggccccacc cagtttccag
     1021 ccctggctta tccccaccac aattccttca gggatcccgg cttccgccag tgaatccaga
     1081 atctgcccca cccctgacgg gtcaataccg atatggtcca gtaactcagc ctcatgaatg
     1141 cgacgcacat attccgccac ttccgccgtg tcatccccga cacgccggac aatggtcatg
     1201 tctccacagg ccacaaaatc ctgaaaccgg gacgcctcgc tcttccgtcg gaccaccgcg
     1261 gtttcatgcg cccaggcatg gccccagccc agccattcgc gggtctcccg gtcacgccca
     1321 atcacataca tccccagcag atcatccagc cctccgccgt caatccccac tgtcaccaca
     1381 tcagcacgca gcaggatatc gtccaggctg atacaacggc cctgctcttc ccagaaatcc
     1441 gcccccgccc agcggtcaga gcgcagggca agaccaattt ccacattggc gtgttttgac
     1501 atgaagcccc ggaatgtctc ttcaccggct tccctggctt ttcgatactc ccggtacaga
     1561 aaggcctcat ccactgaata gccgagattc ggattgacca tggcgaggtt ttccatcagc
     1621 aggtgagccc cgctttccac catttcagga gggtgttcaa agatcaccgg cagaaagtgc
     1681 ggatcatgaa ttttgccgtc gcgcacatcc cgggcgtact gcagtttctg tctgaacacc
     1741 ccggcgggag gttcattcga ctgggtggtc gtatacacca caaacccttc cgggcgggag
     1801 gcaaggccac cgatggcttc acgtaacatg tcctccgcct tgtactgctt gccaaacagc
     1861 cacagctcat caatcagcgt acccacggac ttgataccgg acaccgtatt cggatcggct
     1921 gccaccacct tcagggtggt gtctgtcacc cggtgggtga tggtccggat atgtgtctgc
     1981 acctgacaga ggtcatccag atcatcgtcc cgtcgtacca tatccctggc agggttgaag
     2041 gcgttggctg ccacctccac tgtcggggcc agaatggtgt agcccgccgc ctgccgccag
     2101 ttcagtaaca gtgcagtcat catgatccct gcggccagcg tggacttcga gtttttcttg
     2161 gggataagga taaaaacttc cttgatatgg cgtacaccag tctgcgcatc gtaggagcca
     2221 aacagggccg ccaccaggtc aaacacccac ggtgcacagg actccccgaa cgtcgggcta
     2281 cccggtgcat ccacaatccg cagttgttta aaaatcgcca gtgcatgtgc agcctggtcc
     2341 gggtaaaccg gagccggaat aatcgacagc ccctttttca ggcgctctgc ccagtccggg
     2401 caggcagtgc tccatacagg tatcatccgt tgccctcatt atcgttattc accaccagtc
     2461 ggggtggcgg tggcaccgca aaacggttag ccgctttttt cgcggcatca ccttttgccg
     2521 attttttccc ggtatcccct tttttatggt gcgtgaactg cgccagtcgc caggccgcat
     2581 ccagtgccag tttcggatca attatcaggt tttccacaag gatcctcccc attgctttta
     2641 ccggatctgg aagaccgtct tccatgtaat caataccggg cagtggtgag aggttttgcc
     2701 cgtcatcagg cggcagtgaa accggggagt tcttttcagc cggaggggct tccttatggc
     2761 actcctccgt ctgcatcttt ttctgccggt aaacaggaac ctcatccagc tccaccgtct
     2821 cgcattgttt acgggctata aacgcgagca cttccggatc ttttgccagt tgtgaacctt
     2881 taaccctggc cgtcttcgcc gaataaccgg cagcaatggc tgacgccgtt ttgtttttcc
     2941 cggacatgag cgccagcgca aattttcgtt tttgcgtcgt cagcaccgtc tcctcccggg
     3001 ttcagaactc actcagccgg acatgcttca ggccgtttta tcccgccttt catgcccccg
     3061 aatgttaact gctgcctggt taacatttgc tgaaaaagcc agttaacatt ttttccgcac
     3121 aacaaactga ataataaaga taaaaaccgc aaaaatgccc ggacagccag ttaacatgtt
     3181 aactgccctg aaacgggaat tttttctctg cgtgagaggg ggggcggtgt ccaaagcgat
     3241 ctttttttac gccggatgat accccccccg ggtcgggtta cagtccg
//
LOCUS       DAZUDJ010000193         3246 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.197, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000193 DAZUDJ010000000
VERSION     DAZUDJ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3246
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.197"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..817
                     /gene="nleH"
                     /locus_tag="ACHY1N_005141"
     CDS             <1..817
                     /gene="nleH"
                     /locus_tag="ACHY1N_005141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type III secretion system effector kinase NleH"
                     /protein_id="HFS4047265.1"
                     /translation="PDSRILSSVRDAVASSDNGAQVKVGNRTYRVVVTDNKFCVTRES
                     HSGCFTNLLHRLGWPKGEISRKIEVMLNSSPVNRTMERGAVHSNRPDLPPVDYAPPEL
                     PSVDYNRLPVPGNVIGKGGNAVVYEDAEDATKVLKMFTASQSNEEVTNEVRCFNQYYG
                     AGSAEKIYGDNGDIIGIRMDKINGESLLNISSLPAQAEHAIYDMFDRLEQKGILFIDT
                     TETNVLYDRTRNEFNPIDISSYNISERSWSENQIMQSYHGGKQDLISVVLSKI"
     gene            1041..1865
                     /gene="cif"
                     /locus_tag="ACHY1N_005142"
     CDS             1041..1865
                     /gene="cif"
                     /locus_tag="ACHY1N_005142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000652082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector Cif"
                     /protein_id="HFS4047266.1"
                     /translation="MKDITLPPPTSASCLTGAISVNTEAVLSPMQHTSALHVRDFASL
                     CSQNLKANVLLNSDDHEVPIHQKNPAAIMQNIDSNIKQMATDWGMSIEEVEVIIGREK
                     GIVEPSCGVTANAIMKLFLDKDGFSYCFENEQTLSLEQLQERLSCMPECKSFVLRVND
                     GALGHAYIVDIPKGENSCRPAFLYQSDLGEGVTRKLRFEDWMTHKALTPILLDDICNY
                     FSCMSQNKTDLEQIATLFDIDGNVKMLRKENIQYQKHDNFSFQLFEYDTDNIEKKH"
     gene            complement(2006..2260)
                     /locus_tag="ACHY1N_005143"
                     /pseudo
     CDS             complement(2006..2260)
                     /locus_tag="ACHY1N_005143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332260.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            2417..2992
                     /locus_tag="ACHY1N_005144"
     CDS             2417..2992
                     /locus_tag="ACHY1N_005144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1076 domain-containing protein"
                     /protein_id="HFS4047267.1"
                     /translation="MPLTSDIGSHSFNLGLEVFRARIAANGRGDITVGGETVSIVYDA
                     TDGSFSSSGGNGGLLSELLILGFNNGPRALSERMLSMLSDSGEAQSQEGIQSKISQYK
                     FSVCPERLQCPPESAQCPITLEIPEEGVFIKNSGDSVVCSLFDVTAFSRLVSEKSPHP
                     LTREKLTASMVVSADKCFYDHGKGSFVIKDS"
BASE COUNT          984 a          533 c          759 g          970 t
ORIGIN      
        1 tcctgacagt cgtattttat cctctgtaag ggatgcagtt gctagctcgg ataatggggc
       61 gcaagtaaag gtgggcaaca gaacatatcg tgttgttgtc actgataata agttttgcgt
      121 tacaagagaa agtcatagtg gttgctttac taatctgttg cacaggctgg gatggcctaa
      181 gggagagatt agcaggaaaa ttgaggtgat gctgaattca tcgccagtga ataggactat
      241 ggaaagaggt gctgttcatt cgaatagacc tgatttacct cctgttgatt atgcaccgcc
      301 agagttaccg agtgtggact ataacaggtt gcctgtgcct ggtaatgtta ttggcaaagg
      361 gggtaacgct gtagtatatg aagatgctga ggatgcaaca aaagtcctga agatgtttac
      421 tgcatctcaa agcaatgaag aggtaacaaa cgaagttcgt tgcttcaacc aatattatgg
      481 tgccgggagt gcagaaaaaa tatatggcga taatggcgat attattggta ttagaatgga
      541 taaaataaat ggagaatcgc ttttaaatat ttcgtccttg ccggcacagg ctgagcatgc
      601 catttatgat atgtttgaca ggcttgagca aaaaggaatt ctttttatcg atacaacaga
      661 gacaaatgtc ttatatgatc gcacgagaaa tgaatttaat ccaatagata tatcatctta
      721 taatatttct gaacgttcat ggagtgaaaa tcaaataatg caatcttatc atggaggaaa
      781 gcaagatctt attagtgtgg tattaagtaa aatttagtaa ttttatccag tgtagtggat
      841 ttgttgcatg gatggagttg gtaaaaagtg gtgtggctgg caatccaggc cgcgtcacag
      901 aaatggacaa tgccgctgag agactggcga atggcataca ggcaccagaa aaatttcaga
      961 catgacataa tgcccatgcc agaagttcct tttgcacctc gcctgtattt atagataaac
     1021 atagagtgaa tgaatgagat atgaaagaca ttacccttcc ccccccgacg tccgcgtcct
     1081 gtctgacagg ggccatatct gtaaatactg aagctgtatt atctcccatg caacacactt
     1141 cagccttaca tgtaagagat tttgcttccc tgtgctcaca gaacctcaaa gctaatgtat
     1201 tgctaaatag tgatgaccac gaagtaccta tacatcagaa aaatcctgct gcaataatgc
     1261 aaaatatcga ctctaacatc aaacagatgg caacagactg ggggatgtcg attgaggagg
     1321 ttgaggttat tatagggcga gagaaaggca ttgtggaacc ctcctgcgga gttaccgcta
     1381 atgctattat gaaactattt ctggacaagg atggcttcag ttactgcttt gaaaatgaac
     1441 agacactatc gctcgagcag cttcaggaac gcctgtcctg tatgcctgaa tgtaagagct
     1501 ttgtattacg tgttaatgat ggtgcgcttg gtcatgctta cattgtcgat attcccaaag
     1561 gagaaaactc ttgtcgtcct gcattcttgt atcagtcaga tttaggagag ggcgtcacca
     1621 gaaagttaag atttgaggac tggatgacgc ataaagcatt gactccgatt ttgctggatg
     1681 atatttgtaa ttacttctcc tgcatgtctc aaaataagac agatttggag cagattgcaa
     1741 cgttatttga tattgatggg aatgttaaaa tgttacgaaa ggaaaatatt caatatcaaa
     1801 agcatgacaa ttttagtttc cagttgtttg agtatgacac cgataatatt gaaaaaaaac
     1861 attgagataa taaaatcact atgtagttag cttttgttaa aattgcaatt atttgtaaac
     1921 ataataataa gtattatgac gttaaaattt aaccatacgg taaaatgatt caggaaaacc
     1981 ggttcagcat agcctaggct gaacttttga ggatatcaac gaacggaatt tttgaacatt
     2041 tatgagtaga tcgttgttga agggcttcaa tgagcatgtc aagttcatca actgctggtc
     2101 tacgattacg acggtttgat ttaccaatca aagcaagttt aagtagatat ggacgagcac
     2161 ttttcgccgg gtttgatgtg taattaattc cgtatatagg tttggctgca tccagaacac
     2221 tgccaagata actaacatcg tgactgactg ttgctggacc tacaaatgcc aatcagacgg
     2281 aatgttgaaa ggatagaatg aacagcccga cacacaaaaa acggagtccg gctccggttt
     2341 ttgtgttgcc atataaggca gatgtttgtt acagctattt aagtctggag ttcaaattaa
     2401 aatagggagt tttgttatgc cattaacctc agatattgga tcacattcat ttaatcttgg
     2461 gctggaggtt tttcgtgccc gaattgcagc caatgggcgc ggagatatta cagtaggtgg
     2521 tgaaactgtc agtattgtgt atgatgctac tgatgggagc ttttcatcca gtggcggtaa
     2581 tggcggattg ctttctgagt tattgatttt gggatttaat aatggtcctc gagcccttag
     2641 tgagagaatg ctaagtatgc tttcggactc aggtgaagca caatcgcaag agggtattca
     2701 gagcaaaata tctcaatata agttttctgt ttgtccagag agacttcagt gcccgccaga
     2761 gtctgctcaa tgtcccatta cattggagat accagaggaa ggggtgttta ttaagaattc
     2821 aggggattca gttgtatgta gtttatttga tgttactgca ttttctcggt tagttagtga
     2881 aaaatcacct cacccactga cacgagagaa actaacggca tcaatggttg taagtgctga
     2941 taaatgtttt tatgaccatg gtaagggtag cttcgttata aaagatagtt aaaatatttt
     3001 tctctgagcg aatattagct gtcagtaatt tgtaaaaacg ccacaggcat caagaataca
     3061 agagtatgcc tgtggttgac aggtttcaga tgacttgagg gcgtctttac gtaaatgcat
     3121 ttttctgtgg agatgctgtc ggaaaatatt gggttaaaaa cagaatccaa gtcaaatagt
     3181 aagtttgttt ttttgagatt aggtgtgtgt atttagaatt tttatggtgt gtttattttg
     3241 tggggt
//
LOCUS       DAZUDJ010000194         3225 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.198, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000194 DAZUDJ010000000
VERSION     DAZUDJ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3225
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.198"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..600
                     /locus_tag="ACHY1N_005145"
     CDS             <1..600
                     /locus_tag="ACHY1N_005145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector protein Map"
                     /protein_id="HFS4047268.1"
                     /translation="MTMVGRSLAQAATQTLRPAVTRAATQAGVGASGMKFVPMQSNFM
                     INHGKLTNQLLQAVAKQTRSGDTQQWFKQEQITYISRTVNRAIDDYCMSNNSVIGKET
                     KSHIFKAVESAIKQPLDMNCAQTSIGHFLQSNKYFNKKVDEQCGKGGDPITRFNTQTR
                     MIEQVSQEIFEQKFGGLKVSDIKALTQSTIAQHVQDTRL"
     gene            1047..2663
                     /gene="tir"
                     /locus_tag="ACHY1N_005146"
     CDS             1047..2663
                     /gene="tir"
                     /locus_tag="ACHY1N_005146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001121326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE translocated
                     intimin receptor Tir"
                     /protein_id="HFS4047269.1"
                     /translation="MPIGNLGHNPNVRALIPPAPPLPSQTDGAGGARNQLINSNGPMG
                     SRLLFTPIRNSVADAADSRASDIPGLPTNPLRFAASEVSLHGALEVLHDKGGLDTLNS
                     AIGSSLFRVETRDDGSHVAIGQKNGLETTVVLSDQEFSSLQSLDPEGKNKFVFTGGRG
                     GAGHAMVTVASDIAEARQRIIDKLEPKDTKETKEPGDPNSGEGKIIEIHTSTSTSSLR
                     ADPKLWLSLGTIAAGLIGMAATGIAQAVALTPEPDDPTTTDPDTAASTAEAATKDRLT
                     QEAFQDPDKQKVNIDENGNAIPSGELIDDVVAQIAEQAKAAGEQARQEAIESNSQAQK
                     KYDEQHAKREQEMSLSSGVGYGISGALILGGGIGAGVTAALHRKNQPAEQTITTRTVV
                     DNQPTNNASAQGNTDTSGPEESPASRRNSNASLASNGSDTSSTGTVENPYADVGMPRN
                     DSLARIPEEPIYDEVAADPNYSVIQHFSGNSPVTGRLVGTPGQGIQSTYALLASSGGL
                     RLGMGGLTGGGESAVSTANASPTPGPARFV"
     gene            2796..>3225
                     /gene="cesT"
                     /locus_tag="ACHY1N_005147"
     CDS             2796..>3225
                     /gene="cesT"
                     /locus_tag="ACHY1N_005147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE chaperone CesT"
                     /protein_id="HFS4047270.1"
                     /translation="MSSRSELLLDRFAEKIGIGSISFNENRLCSFAIDEIYYISLSDA
                     NDEYMMIYGVCGKFPTDNPNFALEILNANLWFAENGGPYLCYESGAQSLLLALRFPLD
                     DATPEKLENEIEVVVKSMENLYLVLHNQGITLENEHMKIEE"
BASE COUNT          961 a          605 c          761 g          898 t
ORIGIN      
        1 atgacaatgg taggtagatc gttagctcag gcggctacac aaactcttag acctgcggtc
       61 accagagctg cgacacaagc gggggtggga gccagtggta tgaagttcgt gcccatgcag
      121 tcgaacttta tgattaatca tggcaaactg actaaccagc tacttcaggc cgtggccaaa
      181 caaacccgta gcggtgatac tcagcaatgg ttcaaacagg agcaaattac ttatatatcc
      241 agaacagtaa acagagctat tgatgactat tgcatgagta ataattcggt aattggtaag
      301 gagaccaaaa gccacatttt caaggctgtt gaaagcgcga taaagcagcc tctcgatatg
      361 aattgtgcac aaacgtcgat tggccatttc ttacagtcca acaaatactt taataaaaaa
      421 gttgatgagc agtgtggcaa agggggggat ccaattacac gctttaacac ccagaccagg
      481 atgatagaac aagtctcaca agaaatcttt gaacagaaat ttggtggttt gaaagttagt
      541 gatatcaaag ctctgactca gagcacgatt gcacagcatg tacaggatac tcggttgtag
      601 gaataacctg ttatatatgc gtgttgggca taagttaagc ttcctggtgt atagcgtagt
      661 ctttgctgat gtaagaaaag gctatatacg gaaacttgat atactataaa cttcattatt
      721 tattatattg aaaaagttat ttaattgatt tgttttgtaa ttttaatgct tcaattggat
      781 aagcataaaa tatagtttta tttatagtat gttttattaa agttttacgt ggcatttatt
      841 tttatatcgc atgattattt tcatttaatt acactgatgt gtatttttct gcattatttt
      901 cttgcatcaa aaatcagact gtgatttatt tggtcgatgt tatgttcagc cgtatatcga
      961 ctacgtactg tataccatta cattattatg taatagcaat ataaaggatt attatctatt
     1021 tacataaaat aaaaaggaga cattttatgc ctattggtaa tcttggccac aatcccaatg
     1081 tgagagcttt aattccacct gcaccgccat taccttcaca aaccgacggt gcaggaggtg
     1141 cccgtaatca gctcattaac tcaaatggcc cgatggggtc tcgtttgcta tttacgccta
     1201 taaggaattc tgttgctgat gctgctgatt ctcgtgccag tgatattccc ggacttccta
     1261 caaatccact gcgctttgct gcgtccgagg tatctttgca tggtgcgctt gaagttcttc
     1321 atgataaagg ggggcttgat actcttaact ctgctattgg atcttcgtta ttccgtgttg
     1381 aaactcggga tgatggcagc catgttgcta tcgggcaaaa aaatggcctc gagaccactg
     1441 ttgttttaag tgatcaagag ttttctagct tacagtccct tgatcctgaa ggtaaaaaca
     1501 aatttgtatt tactggaggc cgcggtggcg cagggcatgc tatggtcacg gttgcttcag
     1561 atatcgccga agcccgtcag aggataatag ataaattaga accaaaggat acaaaggaga
     1621 cgaaggagcc aggggatcca aatagtggcg agggaaaaat cattgaaatt catacctcaa
     1681 cctcaacttc tagcctccgt gcagatccta aactttggtt gtcattgggg actattgctg
     1741 caggtctgat agggatggct gcgacgggta ttgcacaggc tgttgcgttg actccagagc
     1801 cggatgatcc aactactacc gatcctgata ctgcagcaag cacagctgaa gctgcgacaa
     1861 aagatcggtt aacgcaggag gcattccagg atccagataa acaaaaagtt aatatcgatg
     1921 agaacggaaa tgcaattccg tcaggggaat taatagatga tgttgttgcg caaatagcag
     1981 aacaagctaa agcggcgggg gaacaggcca gacaggaagc tattgaaagt aattctcagg
     2041 cgcagaaaaa atatgatgag cagcatgcta aacgcgaaca ggaaatgtct ctttcatcgg
     2101 gggttggcta cggtattagt ggggcgctga ttcttggcgg gggaattggt gccggtgtta
     2161 ctgctgctct tcatcggaaa aaccaaccgg cagaacaaac aatcactaca cgtacagtag
     2221 tcgataatca gcctacgaat aacgcatctg cacagggcaa tactgacaca agtgggccag
     2281 aagagtcccc ggcgagcagg cgcaattcga atgccagcct tgcatcgaac gggtctgata
     2341 cctccagtac gggcacggta gagaatccgt atgctgacgt tggaatgccc agaaatgatt
     2401 cactggctcg tattccagag gaacctattt atgatgaggt cgctgcagat cctaattata
     2461 gcgtcattca acatttttca gggaacagcc cagttaccgg aaggttagtg ggaaccccag
     2521 ggcaaggcat ccaaagtact tatgcgcttc tggcaagcag cggcggattg cgtttaggta
     2581 tgggaggatt aacggggggg ggcgagagcg cagtaagtac tgccaatgcc tcaccaacgc
     2641 cgggacccgc acgtttcgtt taaatatatc cgtgagtatt tagttgaggt cgggaggggg
     2701 ggagttttac taatattaat gtttcagaga ataaagttgc agcatgggca actcttgaac
     2761 ttctgtaatt ataaattcaa ttaagagaaa ttataatgtc atcaagatct gagcttttat
     2821 tagatagatt tgcagaaaaa attggtattg gatctatttc atttaatgaa aatagattgt
     2881 gttcttttgc tattgatgag atttattata tttcgttatc tgatgctaat gacgaatata
     2941 tgatgatcta tggcgtctgt gggaaattcc cgacagataa tcctaacttc gctcttgaga
     3001 ttttgaatgc aaacttatgg tttgcagaga atggtggacc atacctgtgt tatgaatcag
     3061 gagcacaatc gctgttgtta gcgttacgtt ttccgctcga tgatgctaca cctgaaaaac
     3121 ttgagaatga aatagaagtc gtcgttaagt caatggaaaa cctgtatttg gtattacata
     3181 atcagggaat aacattagaa aacgaacata tgaaaataga ggaaa
//
LOCUS       DAZUDJ010000195         3220 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.199, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000195 DAZUDJ010000000
VERSION     DAZUDJ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3220
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.199"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(90..617)
                     /gene="mobB"
                     /locus_tag="ACHY1N_005148"
     CDS             complement(90..617)
                     /gene="mobB"
                     /locus_tag="ACHY1N_005148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418293.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobB"
                     /protein_id="HFS4047271.1"
                     /translation="MAGKTMIPLLAFAAWSGTGKTTLLKQLIPALCARGIRPGLIKHT
                     HHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMTETPDEEELDLQFLASRMDTSKL
                     DLILVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLDINDVE
                     GLADFVVEWMQKQNG"
     gene            complement(599..1183)
                     /gene="mobA"
                     /locus_tag="ACHY1N_005149"
     CDS             complement(599..1183)
                     /gene="mobA"
                     /locus_tag="ACHY1N_005149"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HFS4047272.1"
                     /translation="MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALM
                     TQLSHVVVNANRHQEIYQASGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDT
                     PYIPEDLAARLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMAF
                     MRLAGGHAVDFSDNKDAFINVNTPEELARWQEKR"
     gene            1253..1522
                     /locus_tag="ACHY1N_005150"
     CDS             1253..1522
                     /locus_tag="ACHY1N_005150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HFS4047273.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELAD
                     LTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE"
     gene            1599..2585
                     /gene="srkA"
                     /locus_tag="ACHY1N_005151"
     CDS             1599..2585
                     /gene="srkA"
                     /locus_tag="ACHY1N_005151"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response kinase SrkA"
                     /protein_id="HFS4047274.1"
                     /translation="MNNSAFTFQTLHPDTIMDALFEQGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFY
                     FAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLF
                     EDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDL
                     DDARNGPAIQDLWMLLNGDKAEQWMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVY
                     YLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY"
     gene            2602..>3220
                     /gene="dsbA"
                     /locus_tag="ACHY1N_005152"
     CDS             2602..>3220
                     /gene="dsbA"
                     /locus_tag="ACHY1N_005152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HFS4047275.1"
                     /translation="MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEF
                     FSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALG
                     VEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKA
                     AADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSE"
BASE COUNT          805 a          776 c          794 g          845 t
ORIGIN      
        1 aggcccagtc ggaagactgg gcctttttgc gctggtgcag aaaaaggtcg gatgcgacac
       61 tggctgcgtc tgatccagcc tactcttgct tatccgttct gcttttgcat ccactccacc
      121 acaaaatcag ccagcccctc aacatcatta atatccagta atgcgacatc aagattaagc
      181 ggcacatcac tggctacagc aataacatgc ctgtctatca ctaattcttc aggtcgatgt
      241 ccggctccat cgcgaaacag cacaatcttt gcgatctctt catgcttaaa cccttcgacc
      301 agaatcaaat ccagctttga ggtatccatt cgacttgcga gaaactgtag atccagctct
      361 tcttcgtctg gtgtttccgt catcaaggcc catcgttgct ggctggcaac gatggtttgt
      421 gccgcgccag ccttgcgcag ctcatagcta tctttgcctg gcttatcaac atccatatca
      481 tggtgcgtat gcttaatcag ccctggacgg atccctctgg cgcataatgc cgggatcagt
      541 tgtttcaaaa gcgtagtttt tccggtacca ctccacgcgg caaaggcgag taacggtatc
      601 atcgtttttc ctgccatcgg gcaagctcct ctggcgtatt cacgttaata aatgcatctt
      661 tattatcgct gaaatcaacc gcatgaccgc cagccagacg cataaatgcc attacccggc
      721 gttctcctgc ttgcagatat tccagtaata aaggctcaat tgcgcggttt accagagcaa
      781 tagtcgggtg atcgcgttca ccgtcgtgga cccacacgac aggcgcatct ttgcgctgat
      841 gattaagccg ggctgctaaa tcctcgggaa tataaggagt atcgcacgga caaaacaaaa
      901 accactcgcc tgcttcctgc tgcattactg aaagcattcc tgccagaggg cctgggtaat
      961 ccgccagtga atcttcaatc actttcagac cgcttgcctg atagatttcc tgatggcgat
     1021 tggcattaac cacgacgtga gagagctgcg tcataagcgc gtcagcgaca tgttgccata
     1081 atggtttgcc gtttaattca agcaatcctt tatctacgcc gcccattcgt ctggctttac
     1141 cgcctgccag cacaacgcct gttatcgtcg tcatcagatt caccgatatc gcctctttta
     1201 ttgtgggatt gaccctgcta acgtgtctgt ctcaagagta aggagcatta ctatgaaatg
     1261 taaacgtctg aatgaagtta ttgaactcct ccagccagcc tggcaaaaag agccagacct
     1321 taacctgctg caatttttgc agaaactggc gaaagagtca ggttttgacg gcgaactggc
     1381 ggatttgacg gatgacattc tgatctatca tctgaaaatg cgtgattccg cgaaagatgc
     1441 ggtgatcccg ggtttgcaga aagattatga agaagacttc aaaacggcgc tgttacgcgc
     1501 tcgcggcgta attaaagagt aaaagcttgt aagcggcgcc accaaaatca tcgtgaaatg
     1561 atatccttca tcattcgtaa tgttttccgg atgatgggat gaacaacagc gcttttactt
     1621 tccagacact acacccggat accatcatgg atgctctatt tgagcaaggg atccgggtgg
     1681 attccggtct taccccgctt aacagctatg aaaaccgtgt ctatcaattt caggacgaag
     1741 atcgtcgacg ttttgtcgtc aaattttatc gccctgaacg ttggacagcc gatcaaatcc
     1801 tcgaagaaca tcaatttgcg ttgcagctgg taaatgatga agttccggtc gcagcacctg
     1861 tggcctttaa cggtcagact ttattgaatc atcagggatt ttatttcgct gtttttccaa
     1921 gcgtcggtgg tcgccagttc gaagctgata atatcgatca gatggaagcg gttgggcgtt
     1981 atttagggcg tatgcaccag acggggcgca aacagctttt tatccatcgc ccgaccatcg
     2041 gtctgaatga atatctcatt gagcctcgca agctgtttga ggacgctaca ctgatacctt
     2101 ccgggttgaa agcggcattc ctgaaagcga cagatgagct gatcgccgcc gttacagcac
     2161 actggcggga agacttcacc gttctgcggc tacatggaga ctgccacgcc gggaatattc
     2221 tctggcgcga tggtccaatg tttgttgatc tggatgatgc acgtaatggt ccagctattc
     2281 aggatttgtg gatgttgctc aatggcgata aagccgagca gtggatgcaa ctggaaacta
     2341 ttattgaagc ttatgaagaa tttagcgagt tcgacaccgc tgaaatcgga ctgattgaac
     2401 ctttacgcgc catgcgtttg gtttattatc ttgcctggct aatgcggcgt tgggctgatc
     2461 ccgcgttccc gaaaaatttt ccgtggttaa ccggggaaga ttactggctg cgacagacgg
     2521 cgacttttat agaacaggca aaagttctac aagaaccccc tttgcaatta acacctatgt
     2581 attaatcgga gagagtagat catgaaaaag atttggctgg cgctggctgg tttagtttta
     2641 gcgtttagcg catcggcggc gcagtatgaa gatggtaaac agtacactac cctggaaaaa
     2701 ccggtagctg gcgcgccgca agtgctggag tttttctctt tcttctgccc gcactgctat
     2761 cagtttgaag aagttctgca tatttctgat aatgtgaaga aaaaactgcc ggaaggcgtg
     2821 aagatgacta aataccacgt caacttcatg ggtggtgacc tgggcaaaga tctgactcag
     2881 gcatgggctg tggcgatggc gctgggcgtg gaagacaaag tgactgttcc gctgtttgaa
     2941 ggcgtacaga aaacccagac cattcgttca gcatctgata tccgcgatgt atttatcaac
     3001 gcaggtatta aaggtgaaga gtacgacgcg gcgtggaaca gcttcgtggt gaaatctctg
     3061 gtcgctcagc aggaaaaagc tgcagctgac gtgcaattgc gtggtgttcc ggcgatgttt
     3121 gttaacggta aatatcagct gaatccgcag ggcatggata ccagcaatat ggatgttttt
     3181 gttcagcagt atgctgatac agtgaaatat ctgtccgaga
//
LOCUS       DAZUDJ010000196         3072 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.200, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000196 DAZUDJ010000000
VERSION     DAZUDJ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3072
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.200"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            129..2339
                     /gene="katP"
                     /locus_tag="ACHY1N_005153"
     CDS             129..2339
                     /gene="katP"
                     /locus_tag="ACHY1N_005153"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase KatP"
                     /protein_id="HFS4047276.1"
                     /translation="MIKKTLPVLILLALSGSFSTAVAADKKETQNFYYPETLDLTPLR
                     LHSPESNPWGADFDYATRFQQLDMEALKKDIKDLLTTSQDWWPADYGHYGPFFIRMAW
                     HGAGTYRTYDGRGGASGGQQRFEPLNSWPDNVNLDKARRLLWPVKKKYGSSISWGDLM
                     VLTGNVALESMGFKTLGFAGGREDDWESDLVYWGPDNKPLADNRDKNGKLQKPLAATQ
                     MGLIYVNPEGPGGKPDPLASAKDIREAFSRMAMDDEETVALIAGGHTFGKAHGAASPE
                     KCIGAGPDGAPVEEQGLGWKNKCGTGNGKYTITSGLEGAWSTSPTQFTMQYLKNLYKY
                     EWELHKSPAGAYQWKPKKAANIVQDAHDPSVLHPLMMFTTDIALKVDPEYKKITTRFL
                     NDPKAFEQAFARAWFKLTHRDMGPAARYLGNEVPAESFIWQDPLPAADYTMIDGKDIK
                     SLKEQVMDLGIPASELIKTAWASASTFRVTDYRGGNNGARIRLQPEINWEVNEPEKLK
                     KVLASLTSLQREFNKKQSDGKKVSLADLIVLSGNAAIEDAARKAGVELEIPFTPGRTD
                     ASQEQTDVASFSVLEPTADGFRNYYSKSRSHISPVESLIDKASQLDLTVPEMTALLGG
                     LRVMDINTNNSSLGVFTDTPGVLDNKFFVNLLDMSTRWSKADKEDTYNGFDRKTGALK
                     WKASSVDLIFSSNPELRAVAEVYASDDARNKFIHDFVKSWNKVMNSDRFDLNNK"
     gene            2383..2772
                     /locus_tag="ACHY1N_005154"
     CDS             2383..2772
                     /locus_tag="ACHY1N_005154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HFS4047277.1"
                     /translation="MQKSNKVIISCGMALYFLCGGITVAEELDESMQVLARNMSVLQS
                     SMDKKELLEALDRMDDAVDESMKRLPESISPADEEGKNDYIKELQKLEKEIMLAKQKV
                     LSGQLSDIPDSVNKMNKIRVEGHDKFR"
     gene            2886..3072
                     /locus_tag="ACHY1N_005155"
                     /pseudo
     CDS             2886..3072
                     /locus_tag="ACHY1N_005155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          901 a          596 c          785 g          790 t
ORIGIN      
        1 tgcggcttgg aaccccttag tattttttgt ctgtagtatc tatcccagca ataggtatat
       61 cctgttgcat caataaagtt gacttttgta tacaacatgc gaatttccct taatccggag
      121 ctattcgtat gataaaaaaa actcttcctg ttctgattct tctggcgcta tcggggagct
      181 tttctaccgc tgtagccgct gataaaaaag agactcaaaa tttctactat ccagaaacac
      241 tggatttaac tcctctgaga ttacacagcc ctgaatcaaa tccctggggg gctgattttg
      301 attatgccac cagatttcaa cagctggata tggaggctct gaaaaaagat atcaaagatt
      361 tgctgacaac ttcccaggat tggtggcctg cggattatgg tcattatggt cctttcttta
      421 ttcgtatggc ttggcacggt gccggaacat acaggacata tgatggccgg ggaggcgcca
      481 gtggtggtca gcaacgtttt gaaccgctga acagctggcc ggataacgtt aatctggata
      541 aagcccgtcg attgctgtgg ccagtcaaga aaaaatacgg ctccagtatt tcctggggag
      601 acctgatggt cctgactggt aatgttgccc ttgaatccat gggatttaaa acgctgggat
      661 ttgctggcgg aagagaagat gactgggagt cggacctggt atactggggg cctgacaaca
      721 agcctcttgc agataaccgg gataaaaacg ggaaacttca gaaacctctt gccgccacgc
      781 agatgggact tatttatgtc aatcctgaag gccccggtgg aaaaccagat cctctggctt
      841 ccgcgaaaga tatcagggaa gctttttcac gtatggccat ggatgatgag gagactgtgg
      901 ccctgatcgc gggagggcat acatttggta aagcacatgg tgcagcgtct cctgaaaaat
      961 gtattggcgc agggcctgat ggtgcacctg tggaggagca gggactggga tggaaaaata
     1021 aatgtggtac aggaaacggc aaatatacca tcaccagtgg cctggaagga gcctggtcga
     1081 catcgccaac ccagttcaca atgcagtatc tgaagaattt atataaatat gaatgggagc
     1141 tgcacaagag tcctgccggt gcttatcagt ggaagcctaa aaaagcggca aatatagttc
     1201 aggacgcgca tgatccgtct gtcctgcatc cgttgatgat gtttacgacg gatattgctc
     1261 ttaaagttga tcctgaatat aagaaaataa ccacccgttt cctgaatgat ccaaaagctt
     1321 ttgagcaggc attcgcaaga gcatggttta aactgaccca ccgggatatg ggaccggcag
     1381 cccgatatct tggtaatgaa gttcctgcag aatcatttat ctggcaggat cctcttcctg
     1441 cggcggatta tacaatgatt gatggtaaag acattaagtc gctgaaagag caggttatgg
     1501 atttgggtat ccctgcatct gagctgataa agacagcctg ggcttcagct tccacatttc
     1561 gtgtgactga ttatcgtggg ggaaataatg gtgcccgcat caggttacag cccgaaatta
     1621 actgggaagt taatgagcct gaaaaactga agaaagtact ggcatccctg acctcattac
     1681 agcgtgaatt taacaaaaaa cagtctgacg gaaagaaagt gtcgttggct gatttaattg
     1741 ttctttcggg taatgctgca atcgaagatg cggccagaaa agccggggtg gaacttgaga
     1801 ttccctttac tccgggaaga actgacgcct ctcaggagca gacggatgtt gcctcattca
     1861 gtgtactgga gccgacagca gatggattca gaaattatta ctcaaaaagc agaagtcata
     1921 tatcgccggt tgaaagcctc attgataaag ccagtcagct ggatctcacc gttcctgaaa
     1981 tgacggcatt actgggtggt ctgcgggtaa tggatattaa tacaaataat tcttcgttgg
     2041 gagtgtttac cgatacccct ggtgttctgg ataacaagtt ttttgttaat ctgctggata
     2101 tgtcaacacg atggagtaaa gcagataaag aagatacata caatggattc gatcgtaaaa
     2161 cgggagcatt aaaatggaaa gcatcctctg ttgatttaat cttcagttca aatcctgaat
     2221 tacgtgcggt ggcagaagta tatgcctcgg atgatgcgag aaataagttt attcatgatt
     2281 ttgttaaatc gtggaataaa gttatgaata gcgatcggtt tgatttaaac aataaatgat
     2341 aaaactgatg agggagggca cctccctcat gaaggagaaa ttatgcagaa aagcaataaa
     2401 gttataatca gctgtggtat ggcattatat tttttgtgtg gggggattac agtggcagaa
     2461 gaacttgatg aaagcatgca agttcttgca aggaatatga gtgtacttca gtcatcaatg
     2521 gataaaaagg agcttcttga agctcttgac agaatggatg atgctgtaga tgagtcaatg
     2581 aagcgtcttc ctgagagcat ttcaccggct gatgaagaag ggaagaatga ctatataaaa
     2641 gaacttcaaa agcttgaaaa agagattatg ctggcgaaac aaaaagtctt atcgggacag
     2701 ttatcagata tacccgattc ggtaaacaag atgaataaaa tcagagttga ggggcatgat
     2761 aaattcagat aaatcagttg gttgattcct gcgggacgaa tacatacgtc aggaacataa
     2821 ctttatggca gtgaaccgcc ccgggaatcc tggagactaa acttcctgag aaagaggtaa
     2881 acaggatgac taaaaatact cgtttttccc ccgaagtccg tcaacgggcg attcatatgg
     2941 ttctggaaag tcagggcgaa tatgactcac aatgggcggc aatttgttcc attgcccaaa
     3001 gattggctgt acaccggaga ctctgcgtgt ctggggacgc cagcatgagc gggataccgg
     3061 gagcggtgat gg
//
LOCUS       DAZUDJ010000197         3064 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.201, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000197 DAZUDJ010000000
VERSION     DAZUDJ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3064
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.201"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..112
                     /locus_tag="ACHY1N_005156"
     CDS             <1..112
                     /locus_tag="ACHY1N_005156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309530.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HFS4047278.1"
                     /translation="AIPFEGERHNALDDARYQAKYVSVIWQKLIPSQADF"
     gene            171..374
                     /locus_tag="ACHY1N_005157"
     CDS             171..374
                     /locus_tag="ACHY1N_005157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4224 domain-containing protein"
                     /protein_id="HFS4047279.1"
                     /translation="MSSLFLTEDELLILTGCKYASHQRKWLTENGLPFYTNRSGKPIV
                     SRDLFTCNKTLPPREVEPNFGAI"
     gene            374..1424
                     /locus_tag="ACHY1N_005158"
                     /pseudo
     CDS             374..1424
                     /locus_tag="ACHY1N_005158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005105555.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1452..1541)
                     /locus_tag="ACHY1N_005159"
     tRNA            complement(1452..1541)
                     /locus_tag="ACHY1N_005159"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1505..1507),aa:Ser,seq:cga)
     gene            1635..2432
                     /gene="mtfA"
                     /locus_tag="ACHY1N_005160"
     CDS             1635..2432
                     /gene="mtfA"
                     /locus_tag="ACHY1N_005160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HFS4047280.1"
                     /translation="MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAE
                     RFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDE
                     WEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGD
                     RASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSE
                     YFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHRTNDTDSFSATNVH"
     gene            2533..2608
                     /locus_tag="ACHY1N_005161"
     tRNA            2533..2608
                     /locus_tag="ACHY1N_005161"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2566..2568,aa:Asn,seq:gtt)
BASE COUNT          893 a          651 c          701 g          819 t
ORIGIN      
        1 ggctattcca ttcgaaggtg agcgccataa tgcacttgat gacgcccgtt accaggcaaa
       61 atacgtttca gttatctggc aaaaactgat cccgagtcag gctgattttt aatgttcaac
      121 cctaattgcc gctaaccgta tatagttagc ggcggttatg agatatagct atgagtagct
      181 tatttttaac cgaagatgaa ttgctaatat taacgggctg caaatatgca agccaccagc
      241 gaaaatggtt aacggaaaac gggcttccgt tctataccaa tcgtagtggc aaaccgattg
      301 tcagccggga tctatttacc tgcaataaaa ctttaccacc acgcgaggta gagccgaatt
      361 ttggtgcaat ctgatgggaa gacgaaggaa aaatcctgaa cacgaaaaac tacctccaaa
      421 tgtataccca aataaatata gttatgtatg gaaaccaaca tccagagaat ctgtcacact
      481 aaccgccatc aaggatggtt tagctgcttt atggaaaagg tatgaggaaa ctgtaaataa
      541 tcgcgatcgc gcaatgacat tcggtcgctt gtgggaaaaa ttcctcgcca gcgcctatta
      601 cagtgacctc agtccaagaa cacaaaaaga ttatctacaa catcaaaaaa agttgcttgc
      661 cgtattcggt aaggtgccgg cagattccat aaaaccagaa cacatccgtc gatacatgga
      721 caagagaggg gagcagagta aaacgcaagc caaccatgaa aaaagcagta tgtcccgcgt
      781 ttacagttgg gggtatgagc gagggtacgt gaaaggtaac ccatgtgcag gtgtaagtaa
      841 attcaaggcc aaaaaccgcg aacgatatgt aaccgacaaa gaataccagg cagtattaag
      901 cgttgcacct cttcctgttt ttatcgcaat ggaaattgcc tatctgtgtg cagcgagggt
      961 ttccgatgtg ttatcgctga aatgggagca gattggaaac gacggaatct ttatccagca
     1021 agggaaaaca ggaaaaaaac agataaaagc atggagtcca cgattacagg cggcgatcga
     1081 aaaagcaaaa cagttaccaa catccgccta tgtaatcagt aatcaatacg gcaaccgata
     1141 tatgtacaaa ggctttaacg aaatgtgggt agaagcaaga aatcgcgcag gcaaaatttc
     1201 aggtatttta accgacttca cctttcatga tctgaaggcg aaaggaattt cagactatga
     1261 aggaagcagt cgggataagc aacttttctc tggtcacaaa accgaggggc aagtgctaat
     1321 ctatgacagg aaggttaaag tttcaccgac acttgatgtc ccgttacctg aaaatattcc
     1381 aagaaaatat tccaagtaat tccaagtgtg atttttgtca ctgacttaat gatgtataag
     1441 tgattgaatt ttggcggaga gagggggatt tgaacccccg gtggagttgc ccccactccg
     1501 gttttcgaga ccggtccgtt cagccgctcc ggcatctctc cgttcagatg gttgccatga
     1561 tgccaggaaa tttggcattt taacagtccc tgtccgtgca attttgttca agtgacgagt
     1621 ttgcgagcaa aacgatgatt aagtggccct ggaaagtaca agaatcagca catcaaactg
     1681 cccttccctg gcaggaagca ctatcgatcc cccttttaac gtgtctgacg gaacaggaac
     1741 aaagcaaatt agtcactctt gccgaacgtt ttttacagca aaagcggctt gttcctttac
     1801 agggctttga actggattca ttaagaagct gccggatagc acttctattt tgcctacccg
     1861 ttctggagtt aggactggaa tggctggatg gttttcatga agtcttaatt tatcctgcgc
     1921 catttgtggt cgatgatgaa tgggaagacg atatcggtct ggtgcataac caacgtattg
     1981 ttcagtcagg tcagagctgg cagcaagggc ctatcgtttt gaactggttg gatatacaag
     2041 attcttttga tgcttctggt tttaacctga ttattcatga agtcgctcat aagctggaca
     2101 cccgtaacgg cgatcgcgcc agcggagttc cctttattcc gttgcgtgag gttgctggct
     2161 gggaacacga tcttcatgct gcaatgaaca acattcagga agaaatcgaa ttggttggcg
     2221 agaatgcggc gagcattgat gcttatgctg ccagtgatcc tgctgaatgt tttgccgtac
     2281 tttctgaata tttctttagc gccccagaac tttttgctcc tcgtttccct tcattgtggc
     2341 aacgtttctg ccaattttat caacaagatc ctttgcagag actgcatcgc actaatgata
     2401 cagactcgtt ttcggcgacg aatgttcatt aattaacaac tttgcagatt aattaaccaa
     2461 ttgaaatgac ttatgaaatt tagtgttgac agacaaggta ccgctaagta atatgcgccc
     2521 cgttcacacg attcctctgt agttcagtcg gtagaacggc ggactgttaa tccgtatgtc
     2581 actggttcga gtccagtcag aggagccaaa ttctaaaaat tcgctttttt agcgcaatgt
     2641 cactgacctt agttgaacat tgttttttaa cggatagcgg gtttttaaca tcttaagcgc
     2701 cctcgacctt tatggttgag ggcgttttgc tatgaacgcc atcaccattt tcccctcgat
     2761 tataaaactt gagttattca gtagtctccc ctcttgcaac tcacacccaa aactgcctaa
     2821 cgaaaagtta ttaattttca atcatattgc tatcaggatt tacatttttt cgctgtgcta
     2881 gaaagggcgc atttatgtta gctcgttcag ggaaggtaag catggctacg aagaagagaa
     2941 gtggagaaga aataaatgac cgacaaatct tatgcgggat gggaattaaa ctacgccgct
     3001 taactgcggg tatctgcctg ataactcaac ttgcgttccc tatggctgcg gcagcacaag
     3061 gtgt
//
LOCUS       DAZUDJ010000198         3059 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.202, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000198 DAZUDJ010000000
VERSION     DAZUDJ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3059
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.202"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..525
                     /locus_tag="ACHY1N_005162"
     CDS             <1..525
                     /locus_tag="ACHY1N_005162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HFS4047281.1"
                     /translation="VRATAIESTAQRCKKNPIYSPKIVEQSQITAFDKSTNVRRATAF
                     AISVINDKATIPLLINLLKDPNGDVRNWAAFAININKYDNSDIRDCFVEMLQDKNEEV
                     RIEAIIGLSYRKDKRVLSVLCDELKKNTVYDDIIEAAGELGDKTLLPVLDTMLYKFDD
                     NEIITSAIDKLKRS"
     gene            553..1511
                     /locus_tag="ACHY1N_005163"
                     /pseudo
     CDS             553..1511
                     /locus_tag="ACHY1N_005163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312497.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
     gene            1523..1984
                     /gene="yibG"
                     /locus_tag="ACHY1N_005164"
     CDS             1523..1984
                     /gene="yibG"
                     /locus_tag="ACHY1N_005164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HFS4047282.1"
                     /translation="MKACLLLFFYFSLIGQLHGADVKIKENESVMGSTAMTYDLSEEK
                     LMKLKYKSQHGDSEASFRLYQYYCFTKNNIDKQLRFLERSASQGNVTAQFNYGVFLSD
                     TNPTLSEYYNLNRAIYWMEFAVNNGNIDAKSKLQELKKLKRMDRRKNKENP"
     gene            2619..>3059
                     /locus_tag="ACHY1N_005165"
     CDS             2619..>3059
                     /locus_tag="ACHY1N_005165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016158939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Imm57 family immunity protein"
                     /protein_id="HFS4047283.1"
                     /translation="MNNCIFFSISASAVTARQFQRELDLADKAILWALISASTKEGRK
                     ACSLSYFACKAAEAELGLAYMAANDNKEFLTSLSNIMRYKIDAGLSESYTCYLLSKGK
                     IIRPYLKNLNPLQLAADCIETVNKIKDKNKKIIDINSVNICSDDK"
BASE COUNT          995 a          537 c          675 g          852 t
ORIGIN      
        1 gttcgagcta cggcaatcga gtcaacggct cagcgatgca agaaaaaccc aatttattca
       61 cctaaaatag tagaacaatc tcaaattact gcttttgata aatcgactaa tgtcagacgt
      121 gctacagcat ttgctatttc tgttatcaat gataaagcaa caattccact attgattaat
      181 ctgttaaaag atccaaatgg agatgtcaga aactgggccg catttgcaat aaatatcaat
      241 aaatatgata atagtgatat tagggattgt tttgtggaga tgcttcagga taaaaatgag
      301 gaagtccgta ttgaagcaat aatcggactt tcctacagaa aagataaaag ggttttatct
      361 gttttatgcg atgagttaaa aaaaaatact gtttatgatg atatcattga agctgcgggt
      421 gaattaggtg ataaaacgct acttcctgtt ttagatacta tgttgtacaa gtttgatgac
      481 aatgaaatta taacttccgc tattgataag ctgaagcgtt catagcgtga gttgcctatg
      541 cacagtgggg gattcccgcc ggcacggtgc agatgctcga ccggctggaa agtgaaatcc
      601 tggctgaccg ggtgagtgag gaaagccgcc gctggctggc atcgtgcggc ctgaccgtgg
      661 agcagatgaa aaaccagatg gacccggtgt acacgccggc gcgaaaaatc cacctgtacc
      721 actgcgacca tcgcggcctg ccgctggcgc tcatcagcac ggaaggggca acagcgtggt
      781 gcgcagaata tgatgaatgg ggcaacctgc tgagtgatga gaacccgcat catctgcagc
      841 agctcattcg cctgccgggt cagcagtatg atgaggagtc cggcctgtat tacaaccgcc
      901 accgctatta tgacccgctg caggggcggt atatcactca ggatccgatt gggctgaagg
      961 ggggatggaa tttttatcag tatccgttga atccggtcat aaatgtagat ccgcaaggtt
     1021 tggttgatat aaatttatac cccgaaagtg atcttatcca ttctgtagct gatgagatta
     1081 atatcccagg cgttttcaca atcggggggc atggtacccc cacatctatt gaatccgcaa
     1141 cgcgcagtat catgacagct aaagatctag catatctaat taaatttgat gggaattata
     1201 aagatgggat gacagtttgg ttattttctt gtaatacagg taaaggacaa aattcatttg
     1261 ctagccaatt agctaaagag ttacatacaa atgtaatagg acctgacacg ctatggacgt
     1321 ggtgggggcg aggaactaat ggtaagttaa aaatggatac agtgctaaca gcaccaacga
     1381 accttaattc aaataaggat ctaatggcta taacaacaaa agaccttggt aattggataa
     1441 catatgggcc atctgggcac cccatttcta atatgcaagg tacgccagaa aaacccagtg
     1501 atataagata ggttgtagat gtatgaaagc atgcttgtta ctattttttt atttttctct
     1561 tattggtcaa ttgcatggtg ctgatgtgaa aataaaagaa aacgaaagtg tgatgggatc
     1621 tacagcaatg acctatgatt taagtgaaga aaagctgatg aaactgaagt ataaatcaca
     1681 acatggtgat tcagaggcat catttcgact atatcaatat tactgcttta ctaaaaataa
     1741 tattgataaa caattgcgat tcttggaaag atcagcatct caggggaatg ttacagcgca
     1801 gtttaattat ggggtctttt tatcagatac aaatccaaca ttatcagaat attataattt
     1861 gaatagagct atttattgga tggaattcgc tgtaaataac ggtaatattg atgcaaagag
     1921 caaacttcaa gagctcaaaa agctaaagcg aatggataga aggaagaata aggagaatcc
     1981 gtaaaagcaa tagttcatca gactgccgca gcagtagtat gatgatgaat cagggctgta
     2041 ctataactat tatcggtaac attaaccgca gcaggggcgg tataacactc aggctccgat
     2101 tgggctggaa ggttggtgga atttttatca gtatccgttg aacccgattt ctggaatcga
     2161 tccccttggg attagccacc tgtttataca gtataacttt aggtatgctt tcgtgtgttt
     2221 cagatatacc atgtgatgat aatttttatg atgtgcttag tattccagtc gcttctggta
     2281 ataatatgca atgtaaaaat aatccccgtt gtacacattt ataaatagat ggccaatacc
     2341 tcaaggccta tggagttaga atgttaatga cccgggagca agcaatagaa aacctgacgg
     2401 catacgatta gtaccgtcag ttaatacagg aacttataat cgcaatggat tttcaataca
     2461 tagttgttta aacgcttttg gtccgtcttt aggacctcga ttctgttccg agggttgtat
     2521 aactggttta tctaatgaca tgcaaaaatt aaatgagtta atattttcag agccagatag
     2581 cacattaaca gttacggact aaaaaatatg gcaaggttat taacaattgt atttttttct
     2641 ctatttctgc gagtgcagtt actgcaagac aatttcagag agagttagat ttggcagaca
     2701 aagcaatatt atgggcacta atatcagcca gtactaaaga gggacgaaaa gcgtgttcac
     2761 taagctattt tgcctgtaag gccgcagagg ctgaactcgg actggcatat atggctgcga
     2821 atgataacaa ggaatttctc acatccttat ctaatataat gaggtacaaa atagatgctg
     2881 gactttccga atcctataca tgctatttat taagtaaggg aaagatcata agaccatatc
     2941 tgaaaaatct aaatccactc caacttgccg ctgattgcat tgaaacagta aataaaataa
     3001 aagataagaa taaaaaaatc attgatataa attcagttaa tatttgtagt gatgataaa
//
LOCUS       DAZUDJ010000199         3059 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.203, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000199 DAZUDJ010000000
VERSION     DAZUDJ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3059
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.203"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            330..2228
                     /locus_tag="ACHY1N_005166"
                     /pseudo
     CDS             330..2228
                     /locus_tag="ACHY1N_005166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459368.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(2239..>3059)
                     /locus_tag="ACHY1N_005167"
     CDS             complement(2239..>3059)
                     /locus_tag="ACHY1N_005167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS2 family transposase"
                     /protein_id="HFS4047284.1"
                     /translation="VILRRTDDWMDGRRSRHTDDTDVLLRIHHVIGELPTYGYRRVWA
                     LLRRQAELDGMPAINAKRVYRIMRQNALLLERKPTVPPSKRAHTGRVAVKESNQRWCS
                     DGFEFCCDNGERLRVTFALDCCDREALHWAVTTGGFNSETVQDVMLGAVERRFGNDLP
                     SSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISI
                     MPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQWACNGLSDNRCLEI"
BASE COUNT          801 a          684 c          672 g          902 t
ORIGIN      
        1 ttttggcgtt tggttgtgct gctataaatt gaataattca aactttgttg tatattgata
       61 agatatttat ctggtttgtg tttttgatat ttataacgcg tatgtatcaa aaataacatt
      121 atctgcaaca tgttgaaata tcgccctttt atcaatttga tgcgtgtttt tctccatagg
      181 ttatatatgt ccacattcgg acttagggga aagaataatt gaaccattcg tctgtaacgc
      241 agcataatca ttagcgcgaa acataatatg ttttctatgc attgataatt gatggatcaa
      301 cttattacgt ccctgaggag ggatgacaaa tgcactcctg gaaaaagaaa cttgtagtat
      361 cacaattagc attggcttgc actctggcta tcacctctca ggctaatgca actacttatg
      421 acacctggac ttattacgac aatccaacta ccgctcttga ctggagcaat atggatgcac
      481 cgggtactgt agatggtaac tatgtgaatt atagtggctt tgtctactat aacaacacaa
      541 acggtgattt cgataccacc tttaatggtg acactgttaa cgggactatc tctacatatt
      601 acctgaatca tgactttact gatggaacaa caaaccagtt gaacatcagc aactccctga
      661 ttcatggttc aatcacttca atgctgccta tgggtgaaag cagtgatggt cattatgtct
      721 atcagttctc tgaatacggt actgatcgtg taattgatga taattggcat gatggtgatg
      781 tattcacttt aaatattgct aattctacaa ttgatgacga ttatgaaggt ttatacttca
      841 ctgattcata tctggacggt gacgttacca aatatactaa cgaaaccttc cataccccag
      901 ctggtgaagg tgaagaatac gccggtttgt ttgcaaacgg tggtgttggc cttgggctgg
      961 cagtgaatct tgatgtcgaa agtaacatca atatttctaa caactcccgc gttgctggta
     1021 tcagcctgac tcagggtaat accgtaaaca atacttacac tactgaatct catacttggg
     1081 ataacaatat ctcagttacc gattccacag tgacttcagg ttctgtaact actctggaag
     1141 acagtggttt ctatggtaac tctgcggaac ctagtgatta ctctggtaac ggcgaagcta
     1201 atgatgtagc tctgtatttc agtgatagtg cggcttcaaa ttactccatg aaaaacaatg
     1261 tttatttcag caattctact ctgctgggtg atgttgtttt cgcaagtact ttcaacgcaa
     1321 acttctatcc tcaaggtcat gacagtaatg ccgatggcgt actggacacc aatggtggct
     1381 gggctgatga ctcacttaat gttgatgaac tgaatatcac tctggataat ggttctaagt
     1441 gggtaggctc agctactaca tcagcaaatg ttgatgatga atctactgct tcgactgact
     1501 ggtatgatgt tacaggtaat agcctgtatc cgggcgttgt aacagaagca aatgcttggg
     1561 gtcgtacgat tgatgatcaa gtattccaga gcggtgtgtt taacgtcact ctgaataatg
     1621 gttctgaatg gaataccgtt aacgcttcaa acattgatac tttagctgtg aataatggct
     1681 ctcaggttaa tgtgtctgaa tctagcttga tttctgatag catcgctctg accaatggtt
     1741 cttctttgaa cattggagat gaaggttatg ttggaactga tcatctgaca gttgatagct
     1801 acagtactgt agcgctgtct agtgatgaca attcaagtat ctataatggt tattacactc
     1861 cgtcgctgtt agcaaataca ataactgtga ctaacggtgg tttactggat attaatgtag
     1921 accagttcga tgataatccg ttccagactg atactttgga actgaccagc ggcaacatcg
     1981 ctgaccataa cggcaacgta gtgtctggtg tattcgatat ccacagcagc gattatgttc
     2041 tgaacgctga tttggtgaac gaccgtacct gggatacttc caagtctaac tacggctacg
     2101 gtattgttgc tatgaactct gatggtcatc tgactatcaa cggtaacggt gacatgaaca
     2161 acggcgacga actggataac agctctgttg acaacgttgt tgctgcaacc ggtaactaca
     2221 aagttcgtgg atttgcccct atatttccag acatctgtta tcacttaacc cattacaagc
     2281 ccactgccgc agatattccc gtggcgagcg ataacccagc gcactatgcg gatgccattc
     2341 gttataatgc tcgaacgcct ctgcaaggtt ctttgctgcc gttaacccgt ctggtttggg
     2401 catgatactg atgtagtcac gctttatcgt tttcacgaag ctctctgcta ttccgttact
     2461 ctccggactc cgcaccgccg tgttcttcgg ttcaagtccc aacatccggg cgaactggcg
     2521 tgtttcatta gcccggtagc atgaaccatt atccgtcagc cactccactg gagacgacgg
     2581 aagatcgttg ccgaagcggc gttccaccgc tcccagcatg acgtcctgta ctgtttcact
     2641 gttgaagccg ccggtagtca ccgcccagtg cagtgcctca cgatcacagc agtccagcgc
     2701 gaacgtgaca cgcagtctct ctccgttatc acagcagaac tcgaacccgt cagagcacca
     2761 tcgctgattg ctttctttca cggccactct gcctgtatgt gcccgtttcg atggcggtac
     2821 agtaggtttt cgctcaagca acagcgcatt ctggcgcatg atccggtaaa cacgtttggc
     2881 attgatcgca ggcataccat caagttctgc ctgtctgcga agcagcgccc atacccgacg
     2941 ataaccatac gtgggcagct ctccgataac atggtgtata cggagaagca catccgtatc
     3001 atcagtgtga cgactgcggc ggccatccat ccagtcatcg gttcgtctga gaatgacgt
//
LOCUS       DAZUDJ010000200         3049 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.204, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000200 DAZUDJ010000000
VERSION     DAZUDJ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3049
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.204"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..172
                     /locus_tag="ACHY1N_005168"
     CDS             <1..172
                     /locus_tag="ACHY1N_005168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFS4047285.1"
                     /translation="RLAGKMTPYSHHLDAGRFSVKTGEAGNGHAFTQVKFTPKGVQWI
                     AGLLAAWRATAA"
     gene            267..398
                     /locus_tag="ACHY1N_005169"
     CDS             267..398
                     /locus_tag="ACHY1N_005169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047286.1"
                     /translation="MSDKLIMLAKGLCVIVGISFSLMLVALFLSITWMALTSAGLVG"
     gene            621..806
                     /locus_tag="ACHY1N_005170"
     CDS             621..806
                     /locus_tag="ACHY1N_005170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rz1 family lipoprotein"
                     /protein_id="HFS4047287.1"
                     /translation="MRELKMKLCVLMLPLVVSACGSTPPAPVPCVKPPAPPEWIMQPA
                     PDWQTPLNGIISPSESG"
     gene            1045..1596
                     /locus_tag="ACHY1N_005171"
     CDS             1045..1596
                     /locus_tag="ACHY1N_005171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HFS4047288.1"
                     /translation="MNYPTIVNGIDFRDLVFVTGNEPVTDTRKVAVAFGKEHKDVLRK
                     TRAVVQQCSKEFAERNFALCYENNELQNGKPQPIYRMTKDGWTMLVFGFTGKAAMTFK
                     EAYIQAFNWMAELIQQGLANLEAERNAVMLEYMKEKDVASMSGRLLNRWGRVKKPQLL
                     ARLDRLEQQGQIALPGFDKGISA"
     gene            1942..2268
                     /locus_tag="ACHY1N_005172"
     CDS             1942..2268
                     /locus_tag="ACHY1N_005172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="HFS4047289.1"
                     /translation="MKRNLPLIILLSSLVMGCTQHKTDMPRQLVKALPQYPAYAAANY
                     IKGRVDVKFDIGADGTVTRIEFIRSEPHHLFDEQVVKAMAKWRFEKDRPCKGVKKTFI
                     FSPSAP"
     gene            complement(2400..2600)
                     /locus_tag="ACHY1N_005173"
     CDS             complement(2400..2600)
                     /locus_tag="ACHY1N_005173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HFS4047290.1"
                     /translation="MSSKNRTRRTTTRNIRFPNHIIEQINIALEHKGSGNFSAWVIEA
                     CRRRLATDATHLRPASMTNNEK"
     gene            2642..3007
                     /locus_tag="ACHY1N_005174"
     CDS             2642..3007
                     /locus_tag="ACHY1N_005174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001427183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFS4047291.1"
                     /translation="MAELRTLQSRIKTLNTRRVNILKGEQRRVSGSARVSLKRHIWLR
                     DAGQCCLCGRVVDLCDSELDHRIALQFGGGNEETNLWTLCTECHRQKSAREAAGGMPD
                     PTLPEVSGGHGRADDIIGL"
BASE COUNT          739 a          674 c          852 g          784 t
ORIGIN      
        1 tcgcctcgct ggaaaaatga cgccttactc gcatcacctg gatgcggggc ggtttagcgt
       61 gaaaacgggc gaggcgggca atggtcatgc ttttacgcag gttaaattca ccccaaaagg
      121 tgttcagtgg attgctggtc tgcttgctgc atggagagct accgcagcat gaagatgata
      181 aaaatggact ggaaattttt gctggtctgg ctgattccgt ttttatgggt ggttgcccgg
      241 ttaattactg ctattaagag gtaaagatgt cagacaaact cataatgctg gcgaagggcc
      301 tttgtgtaat cgtcggtatt tcattttcac taatgctggt tgctcttttt ctttccataa
      361 cctggatggc gttgacttcg gcagggctgg tggggtgagc ataaaccgaa tgctttccgc
      421 gtttaccgtt attctgctgg tggtctgtag tgcgctgtgg ctggcaacag accattaccg
      481 tgataacgcc atcacctaca aagcgcagcg cgataaaaaa gccagagagc tggagctggc
      541 aaacgcaacc attactgaca tgcagcagcg ccagcgtgat gttgctgcgc ttgatgccag
      601 atactcaagg gaattagccg atgcgagagc tgaaaatgaa actctgcgtg ctgatgttgc
      661 cgctggtcgt aagcgcctgc ggatcaacgc cacctgctcc ggtaccgtgc gtgaagccac
      721 cggcacctcc ggaatggata atgcaaccgg cccccgactg gcagacaccg ctgaacggga
      781 ttatttcacc ctcagagagc ggttgatgac aatgcagaag caactggaag gggcgcagga
      841 atatatccgc actcagtgcc tgaattaaca gagccagctt aatcgctggc tttttcatat
      901 ctgaatttca tcgcgcatct cacgcgcata tcacatcccc gagcctttca gaaagttgag
      961 cctgagaact gtcgtatatg gtggcgacca tctcggggcg gcttttctgt gagacaggct
     1021 caattttctg aaaggtaaga cgctatgaac tatccgacga ttgttaacgg tattgatttc
     1081 cgcgatcttg tttttgtgac aggcaacgag ccggtgacgg atacccgaaa ggttgccgta
     1141 gcatttggca aagaacacaa agatgtattg cggaaaacaa gagccgttgt tcaacaatgc
     1201 tcaaaagaat ttgcagagcg caattttgcg ctttgctatg aaaacaatga gttacagaac
     1261 ggtaaacccc agcccatata tcgaatgaca aaagacggtt ggacgatgtt ggtatttggt
     1321 tttacgggga aagctgctat gacctttaag gaagcgtaca ttcaggcttt caactggatg
     1381 gctgagctta ttcagcaagg tctggcgaat ctggaggcgg agcgcaacgc tgtaatgctg
     1441 gagtacatga aagagaaaga tgtcgccagt atgtcaggtc gtttgctcaa tcgctggggc
     1501 agggtgaaga agcctcagtt gctggcaagg ctggacaggc tggagcagca ggggcagatt
     1561 gcgttacccg gatttgataa aggcatttca gcctgacata gccatgcgcc gtatcgtcgc
     1621 cgtatcgtcg ccgtatcccc gcattaacag agaccgcagc ccgacaggga gactcctcta
     1681 cgagagtgtg cgggataatc aaaaacgata cacaccgggg tttaccgcgt taacggagcg
     1741 cggcgttgtc cctcatggtc gctggtccgg tgcgatggtg gaagaaaccg gacgatgtgt
     1801 tacctcgcaa gctctgtgat gtcatgtgtc tgatttgtga tttaagtcgg ataattgtcg
     1861 ttgccattaa gcagaggatt gatgaccgac agggtggcat tgttagaata agacttattc
     1921 ttatctgtgc cgggaatgaa aatgaaaaga aatcttccgt taattatttt gttgtcttct
     1981 ctggttatgg gctgtacgca acataaaaca gatatgcccc gacagttggt taaggcatta
     2041 ccacaatatc cggcctatgc agcggcaaat tatataaagg gacgggttga tgtgaagttt
     2101 gatattggtg ctgatggtac tgtcacccga attgagttta tccgttcaga gccgcaccat
     2161 ttgtttgatg agcaggttgt aaaggcgatg gcaaaatggc gatttgagaa ggacaggccg
     2221 tgtaaaggcg tgaagaaaac gtttatcttt agtccttctg caccctgatt atttcatcag
     2281 aaattaatta tcactctgtt gttattctgt acatcccggc agggtaagtc ttgttccgtc
     2341 ggatatgaag atgaaatatt gttggaggac agtgggtacc tgctcctgta accgaacgtt
     2401 catttctcgt tatttgtcat gctggccggg cgcagatgcg ttgcatctgt tgccagcctt
     2461 ctcctgcagg cttcaataac ccacgctgaa aagttaccgg accctttatg ctcaagggct
     2521 atgttgattt gttcaattat gtgattgggg aaacggatat tgcgggttgt ggttctgcgg
     2581 gtccggtttt tcgatgacat tttctttcct ctggtgacaa gttatatgac ggggatttta
     2641 catggctgag cttcgtacac tccagagcag aatcaaaaca ctgaataccc gacgggtgaa
     2701 tattctgaag ggggaacagc gtcgtgtcag tggcagtgcc cgggtttccc tcaagcgtca
     2761 tatctggctg agggatgccg ggcagtgctg tctctgtggt cgtgtggttg acctctgtga
     2821 cagtgaactc gatcaccgca ttgcacttca gttcggtggt ggtaatgagg agacgaatct
     2881 ctggacgctc tgcaccgaat gccatcgaca aaagtctgct cgtgaagcgg cgggtggtat
     2941 gccggacccg acgctgccgg aggtgtccgg aggtcatggc agggcagacg atatcatcgg
     3001 actgtgaccc gccccggggg ggatcatccg gcgaaaaaaa cgatcgctc
//
LOCUS       DAZUDJ010000201         2992 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.205, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000201 DAZUDJ010000000
VERSION     DAZUDJ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2992
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.205"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..96)
                     /gene="escE"
                     /locus_tag="ACHY1N_005175"
     CDS             complement(<1..96)
                     /gene="escE"
                     /locus_tag="ACHY1N_005175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312614.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YscE family type III secretion system
                     co-chaperone EscE"
                     /protein_id="HFS4047292.1"
                     /translation="MITITELEDEIIKNKEAANIFIEKINDKKNEI"
     gene            complement(111..482)
                     /gene="ler"
                     /locus_tag="ACHY1N_005176"
     CDS             complement(111..482)
                     /gene="ler"
                     /locus_tag="ACHY1N_005176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312615.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE master regulator
                     Ler"
                     /protein_id="HFS4047293.1"
                     /translation="MNMETNSHTTSPYIQLIEQIEVLQQEAKRLREQEIQSVIESIQK
                     QITYYNITLQELGYTNVPDDGLARRNSSKGVYYRNEEGQTWSGVGRQPRWLKEALLNG
                     MKKEDFLVKDTEDEIIPLKNI"
     gene            1683..2828
                     /locus_tag="ACHY1N_005177"
     CDS             1683..2828
                     /locus_tag="ACHY1N_005177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EspG domain-containing protein"
                     /protein_id="HFS4047294.1"
                     /translation="MINGLNNNSASLVLDAAIRINSDFKKQWNDMSCAEKLLKVLSFG
                     LWNPTYTRSERQTFQELLTVLEPVSPAPNELGRIYANFADGSSLRISVTNSELVEAEI
                     RTPDNEKILMLLESNEQNRLLQSLPINLHMPYIQVHRALSKMDLTDHKSMHNLLSFTS
                     KLSATLIPHNTQTDPFSGPTPFSSMFMDTFRGLGNAKLSLNGVDIPVDAQKLLRDALG
                     LKDTHSSLARNVINNGISRHHAEQIARESSGSDKQKAEVVEFLCHPEAATAICSAFYQ
                     SFNVPALMLTHTRISQAREYNVERSLDVPNACINISISQSPDGSIHVASHTGILIMAP
                     EDRPNELGMLTNRTSYEVPQGVKCEIDEMVRTLQPRYGASETYLKNI"
BASE COUNT          974 a          615 c          500 g          903 t
ORIGIN      
        1 gatttcgttc tttttgtcgt ttattttttc aatgaaaata tttgcggctt ctttattttt
       61 tattatttcg tcttccagtt cagttatcgt tatcatttaa tgatttcatg ttaaatattt
      121 ttcagcggta ttatttcgtc ttcggtgtcc ttcacaagaa aatcttcttt cttcattcca
      181 ttcaacagtg cttctttaag ccagcgtggc tgtcggccaa ctcccgacca ggtctgccct
      241 tcttcattgc gataataaac tcctttcgat gagttccggc gagcaaggcc atcatcaggc
      301 acattagtat atcccagctc ttgtagggtt atattgtaat aagtaatctg cttttgaatc
      361 gactcaatta cactttgaat ttcctgctct cgcagtcgct ttgcttcctg ttgtaacact
      421 tcaatttgct caataagctg aatgtatggg cttgttgtgt gcgaattagt ttccatattc
      481 ataataaata atctccgcat gctttaatat attaagctat tagcaatctt atccttatca
      541 ggaaggatca acaattaatc gaatgatata aattatgtga gataacgttt tatctatcaa
      601 attagaacac atctacttca tcaaacaaaa tccttataaa agttattaat caccgatgta
      661 taatgtgtaa aacacattat cattaaatgt caacaaaaaa atcatatttc ttaaaaatca
      721 ttcaaaatca ataaagtaga agaacttcat ctctttagca aacgccatta acaattgcct
      781 ttccatttag ttaatcgttt tgttttcttt aagattagtc ctattagaca aatagcaaaa
      841 tggaataact acagcactaa gacgttccgc tatatagcta ttacctgttc ccctgacata
      901 aggagcagat atacctcaac cccctattcc ccagtgctga ccgggagcgg cggcggtata
      961 aaaaggaaca aatggcagaa caagcaacca tgtttgtccc ccccgcataa ccgtaccatt
     1021 cgcattaaga aatattccca tatctatccc gcaaaagagg acccgtcata catcaagtcc
     1081 gttttactgg gcatcagatt atcgccgtaa ttagctcagt gaaagccggg taaacggtta
     1141 gcaagctcag tggctcaaaa gtgcatagcg ctaagatggg cctggttaca cctgcccttt
     1201 gctgcagatc gtgttgatcg gtgtgatgcc gccacacgtt taagtcaatc tggaaaactc
     1261 acaatgcgct cttctataaa gaggactctt tgataaagta acccgaaaag ggaaagctaa
     1321 ctgatatcaa tgtaccacct tagtaatcat cccttatata cagacaaaaa gaagttgcct
     1381 gaaagccagg tatctaaact aatcactaat ggtatatttt atcagcacaa taaaaatttt
     1441 ttctgaatgc tattattaat gtaaataatt acaacctttt cgtaggcaca aaaactattg
     1501 ctgatgaatc aatgaaaatc tattgttcgt cattagagga gtatttcctc taatttaaaa
     1561 aaataactct ctatacattt aaaactctcg ctataaatag cttatatatt attgacacta
     1621 tatcatgcta tatgatatct gttgtcgaat cattcataat aaatgagata ggggaatctc
     1681 tcatgataaa cggacttaat aataattccg catctttagt tttagatgct gcaattagaa
     1741 ttaattctga ttttaaaaag cagtggaatg atatgtcatg cgctgaaaaa ttactaaaag
     1801 ttcttagttt tggtttatgg aatccaacgt atactcgtag tgaaaggcaa acatttcaag
     1861 agttgttaac cgttttagaa cctgtatctc ccgcgcctaa tgaattgggc agaatatatg
     1921 ctaattttgc agatggctca tccttaagaa tttccgtcac taacagcgaa cttgttgaag
     1981 ccgagattcg cacaccagat aatgaaaaga ttcttatgct cctggagtca aacgaacaaa
     2041 ataggttatt acaatcttta cccatcaatc tccacatgcc atacattcag gttcatcgtg
     2101 ccttatctaa gatggacctg actgatcata agtcaatgca caatctactt agttttacgt
     2161 caaaactatc agcaaccttg attcctcata atactcaaac agatccgttt tccgggccta
     2221 caccattcag ctctatgttt atggatacat ttcgaggact cggcaatgca aagctttcac
     2281 tcaatggtgt tgatatacct gtagatgcac aaaaattgct tcgcgatgca ctaggactta
     2341 aagacacaca ttcatcactt gcccggaatg ttataaataa tggtatttct cgtcatcatg
     2401 cagagcaaat agcaagggaa agcagcggca gcgataaaca gaaagctgaa gttgtggagt
     2461 ttttatgcca ccccgaagcg gcaacagcca tatgctcggc tttctatcaa tctttcaatg
     2521 tgccagcctt aatgttgaca catacaagga tctctcaagc cagagaatac aatgtggaaa
     2581 gatcgttaga tgtacctaac gcgtgcatta acataagtat ctctcaatca ccagatggaa
     2641 gcattcacgt tgccagccat accgggattc tgataatggc gccagaagac cgccccaacg
     2701 agttaggaat gttgacgaac aggacctcct atgaagtgcc acaaggtgtg aaatgtgaaa
     2761 tcgatgagat ggtaagaacg ctacaaccaa ggtatggcgc atctgaaaca tacctgaaaa
     2821 acatttaaaa ataaaaaaat ggacaccaca cactttattt atcaaaacaa acaataacta
     2881 atcacactca caattattaa taatttaacc tcacagcaat catacaaaac aaagatattt
     2941 atttcgcaaa ccatttatag cgaatggaga aggaatgaaa agaagcttat tt
//
LOCUS       DAZUDJ010000202         2980 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.207, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000202 DAZUDJ010000000
VERSION     DAZUDJ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2980
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.207"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(1..1110)
                     /locus_tag="ACHY1N_005178"
                     /pseudo
     CDS             complement(1..1110)
                     /locus_tag="ACHY1N_005178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559742.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EscU/YscU/HrcU family type III secretion system
                     export apparatus switch protein"
     gene            complement(1119..1886)
                     /gene="sctT"
                     /locus_tag="ACHY1N_005179"
     CDS             complement(1119..1886)
                     /gene="sctT"
                     /locus_tag="ACHY1N_005179"
                     /inference="COORDINATES: protein motif:HMM:TIGR01401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030254 - protein secretion by the type III
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system export apparatus
                     subunit SctT"
                     /protein_id="HFS4047295.1"
                     /translation="MGEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRH
                     PIIIVVSCALVQHYHYELLNLNEIDIALFAAREIIIGLFIACLSASPFWMFLAIGSFI
                     DNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTKGGMNFILETLWQSYNLWPSG
                     NFNFPKLEPLFSYINNIMTHTIVYASPVIAVMLGGEAVLGLLACYASQLNAFAISLTV
                     KSALAFLILIIYFAPILAERVMPLSFFPEQLQLYIEK"
     gene            complement(1888..2148)
                     /locus_tag="ACHY1N_005180"
     CDS             complement(1888..2148)
                     /locus_tag="ACHY1N_005180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscS/YscS/HrcS family type III secretion system
                     export apparatus protein"
                     /protein_id="HFS4047296.1"
                     /translation="MDDIVFAGNRALYLILVMSAGPIEVATFVGLLVGLFQTVTQLQE
                     QTLPFGVKLLCVSICFFLMSGWYGEKLYSFGIEMLNLAFARG"
     gene            complement(2158..2823)
                     /locus_tag="ACHY1N_005181"
     CDS             complement(2158..2823)
                     /locus_tag="ACHY1N_005181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscR/YscR/HrcR family type III secretion system
                     export apparatus protein"
                     /protein_id="HFS4047297.1"
                     /translation="MSNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRNALGLQ
                     QVPSNMTLNGVALLLSMFVMMPVGKEIYNNSQNENLSFNNVASVVNFVETGMSGYKSY
                     LIKYSEPELVSFFEKIQKVNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYI
                     YLPFVVVDLVISSVLLTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLS
                     INP"
     gene            complement(2813..>2980)
                     /locus_tag="ACHY1N_005182"
     CDS             complement(2813..>2980)
                     /locus_tag="ACHY1N_005182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HFS4047298.1"
                     /translation="DDLCAKRIISLLPESEKNIEIRVNGALTGYGELVEVDDKLGVEI
                     HSWLSGNNNVK"
BASE COUNT         1002 a          608 c          473 g          897 t
ORIGIN      
        1 aattatcgtc tttattctcg atttttgtgt cttcaccctc aatgaattta tcttctgaag
       61 agagctgttc atcttgaaca ggttgcccag cattctccac atcttcaagc cacagcagaa
      121 gacgtaatat ttcatctata ttttcgaagc taacataatc gtagcgacga tgggtagcat
      181 aattttttcg tgctaatttt ttatctgtga taattggtat tccgatttcc tttgcatatt
      241 tccttacgcc taaggccacc tcattagtta ctcttacaga aatcaatgga ataggtgaaa
      301 gatgtggctt aaagtatatc cctattgcaa tgtgagtagg gttggaaatc atcaaacgac
      361 tattactgac atcagacttc aattgctcag aaagaatttc ctgatgcgct ctctgcgttt
      421 agacttaatt tctggatttc cttcttgctc cttgtattct cttttaactt cttgtttatc
      481 cattttcata tctttcataa ataaaaaata ttcagcgata aaatcaaaaa ttaagacaat
      541 tatcatactg ccgagacaat acagtatgag aaggaatagc atctctcccc aatctgataa
      601 taaagatatg atatctccat caagagtttt aaaaagcagt gatttatgat tactccaaaa
      661 tactttgatc gccaatgcaa aaaaaacaat ataaagaatt gctttaacaa attcttttac
      721 ggtttttaag ccaaatatac gctttaagcc atttactgga ttcaatgaat caaacttaaa
      781 tttaacagct tcagttgcta attgcatttt actttgaaac caggagacaa gtattgttgt
      841 gaacatgcaa accagcaaaa aaggaatgtt cgttttcaac caaccaaccc ccatagcttt
      901 aaaatagtcc caaatatctg gtttagcgtt atgatcaagg atgtattcaa gaatcgacat
      961 aatgtgatgc acatcaaaaa catatccgag atataaagta cccacaagca ttattacaga
     1021 gatggttaag tctctacttt ttagaatttg ccctttttta gaagcatcct ggagtttctt
     1081 ttgtgttggc ttttcagttt tattggccat gaaacactct atttctcaat gtatagttgc
     1141 aattgttctg ggaaaaagga taacggcatt actcgttcag ccagtattgg ggcaaaataa
     1201 ataattaata ttaaaaatgc cagcgcactt ttgacagtca gtgaaatggc aaaagcattt
     1261 agttgtgaag cataacatgc cagcaatccc aggacagcct caccgcccag cataacggca
     1321 atcacggggc ttgcgtaaac gatagtatga gtcattatgt tattaatata tgagaataaa
     1381 ggctctaatt taggaaaatt aaaattgcct gaaggccata aattataact ttgccaaaga
     1441 gtttccagaa taaagttcat tccaccttta gtaagataaa ccgcagcaga gaaaaggtta
     1501 aataatcttg ctaattccga ggtatcgaca cctgtagccg gatccaaagt actacttaat
     1561 gttgcaccgc gttggttatc gataaagcta cctatagcaa ggaacatcca aaacggggat
     1621 gctgataagc atgcaataaa cagccctatg ataatttctc tggcagcgaa caaagcaata
     1681 tcgatttcat ttaagttcaa taattcatag tggtaatgct gaactaatgc acatgatacc
     1741 actattatta ttgggtgacg aactactgtt ggtatattcc cactggcgaa aaatggtaac
     1801 aaatagaaag ttggtgccaa tcggcaaaaa ccgagcgctg tagcagccag cagactatgc
     1861 aactgataga gtatcgcctc ccccatgcta tcctctcgcg aatgctaaat tcagcatttc
     1921 gataccaaat gaatataatt tttcaccata ccacccgctc attaaaaaaa agcaaatact
     1981 tacgcacaat aatttcacgc caaatggcaa cgtctgttct tgcaactgcg ttaccgtttg
     2041 aaaaagccct accaataaac caacaaatgt cgcaacttca ataggtcctg cagacataac
     2101 taaaatcaga tacagcgccc tattccccgc aaaaacaata tcgtccatat tttttcctca
     2161 gggattaatg gataggtcaa aatattgtaa aatgagccct tttgataaca ttgtccaacc
     2221 gtccatcgcg acaaacaaaa ttaattttat cggtgtagat atggttaccg gactcatcat
     2281 catcatacct aacgttaaca gaacgctgga tataaccaga tccactacga caaagggtaa
     2341 atagatataa aaacctataa taaatgcact ttttatctca ctcaatgcat atgcgggcag
     2401 taacgagaaa attgaaatat tatcatcatc gattatctct tcattgtctt cagaactatt
     2461 caccttctga atcttttcaa aaaagctaac caactcaggt tcagaatatt ttatcaaata
     2521 tgatttataa ccactcatgc ctgtctcaac aaaattaaca accgatgcta cattattgaa
     2581 tgaaagattc tcattctgac tgttattata tatttccttc ccaaccggca tcattacgaa
     2641 cattgacaat agcaaagcaa ccccattaag tgtcatattt gatggcactt gctgaagtcc
     2701 cagcgcgttt cggacaataa caaaaacaat cgagaattta ataaaacatg tcccggatgc
     2761 tattataaac ggcaatagtg taaataatga taatatcgct atcagcgaaa tgctatttga
     2821 cattattatt ccctgataac caagaatgaa tttctacgcc caatttatca tccacttcaa
     2881 caagttcgcc atagccagtt agcgcaccat ttacacgtat ctctatattt ttctcagatt
     2941 caggaagcag agatattatt ctttttgcac agagatcgtc
//
LOCUS       DAZUDJ010000203         2945 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.208, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000203 DAZUDJ010000000
VERSION     DAZUDJ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2945
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.208"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..810
                     /locus_tag="ACHY1N_005183"
     CDS             <1..810
                     /locus_tag="ACHY1N_005183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein"
                     /protein_id="HFS4047299.1"
                     /translation="DFLNGDPDQPIIMGRTYHQENRTPGSLPGTKTQMTIRSKTYKGS
                     GFNELKFDDATGKEQVYIHAQKNMNTEVLNNRTTDVINNHAETIGNNQMIAVTNNQIQ
                     TVGVNQIETVGSNQIINVGSVQVETIGLVRALTVGVAYQTTVGGIMNTSVALMQSSQI
                     GLHKSLRVGLGYDVKVGNNVTFTVGKTKKDDTGQTAIYSAGEHLELCCGKARLVLTKD
                     GQIFLNGTKIHLQGKEQVNGDSLLINWNCAASKSPPKTPDEKQDTPDMREY"
     gene            877..>2945
                     /gene="rhsD"
                     /locus_tag="ACHY1N_005184"
     CDS             877..>2945
                     /gene="rhsD"
                     /locus_tag="ACHY1N_005184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhs element protein RhsD"
                     /protein_id="HFS4047300.1"
                     /translation="MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMT
                     SGNPVNPLLGAKVLPGETDLALPGPLPFILSRTYSSYRTRTPAPVGVFGPGWKAPSDI
                     RLQLRDDALVLNDNGGRSIHFEPLLPGEAVYSRSESMWLVRGGKAAQPDGHTLARLWG
                     ALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLPPYRVLTGLADRFGR
                     TLTYRREAAGDLAGEITGVTDGAGREFRLVLTTQAQRAEEARTSSLSSSDSSRPLSAS
                     PFPDTLPGTEYGPDRGIRLSAVWLMHDPAYPESLPGAPLARYTYTEAGELLAVYDRSN
                     TQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGLSYRYQYEQDRIT
                     VTDSLNRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGL
                     NVVSGDITDITTPDGRETKFYYNDGNQLTAVVSPDGLESRREYDEPGRLVSETSRSGE
                     TVRYRYDDAHSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGYQTRYEYDRFGQMTA
                     VHREEGISLYRHYDNRGRLTSVKDAQGRETQYEYNAAGDLTAVITPDGNRSETQYDAW
                     GKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHTEFSWDVLDRLIQQRGFDGRTQRYR
                     YDLTRKLT"
BASE COUNT          668 a          809 c          967 g          501 t
ORIGIN      
        1 gacttcctca acggcgatcc ggaccagccg attattatgg ggcgtaccta ccaccaggaa
       61 aaccgcacac ccggcagcct gccggggacg aagacgcaga tgaccattcg ttcgaaaacc
      121 tataagggca gcgggtttaa tgaactgaag tttgacgatg cgacagggaa agaacaggtc
      181 tacatccacg cgcagaagaa catgaacacc gaggtgctga ataaccgcac cacggatgtg
      241 ataaacaacc atgctgagac cattggcaac aatcagatga ttgcggttac caacaatcag
      301 atacagacgg tgggcgttaa ccagatagag acggtgggca gtaaccagat cattaacgtg
      361 ggttctgttc aggtggaaac gattggactt gttcgtgcgc tgaccgtggg cgtggcgtac
      421 cagacgacgg taggtggcat tatgaacact tcggtggctc tgatgcagtc ctcgcagatc
      481 ggtttgcata aatcgttgag ggtcgggctg ggttatgacg tcaaagtcgg aaataacgtt
      541 accttcaccg ttggtaaaac gaaaaaggat gataccgggc agaccgcgat ttactccgcc
      601 ggtgagcatc tggagctctg ctgtggtaag gcaaggctgg tgctgacgaa ggacggacaa
      661 atttttctca acggcacaaa aattcatttg cagggtaagg agcaggttaa tggtgactca
      721 ctgttgatta actggaactg tgcagcctcg aaatccccac cgaagacccc tgatgaaaag
      781 caggatacgc cggatatgag agagtactga tcccgtacct gttcggtatt cagtaacaaa
      841 caagcattaa aaataaacag aagaaggaat tgaatcatga gcggaaaacc agcggcgcgt
      901 cagggagata tgactcagta tggcggtcct attgtccagg gttcggcagg tgtaagaatt
      961 ggcgcgccca ccggcgtggc gtgctcggtg tgtccgggcg ggatgacttc gggcaacccg
     1021 gtaaatccgc tgctgggggc gaaggtgctg cccggcgaga cggaccttgc gctgcccggc
     1081 ccgctgccgt tcattctctc ccgcacctac agcagctacc ggaccaggac acccgcgccg
     1141 gtgggagtgt ttggccccgg ctggaaagcg ccttctgata tccgcttaca gctacgcgat
     1201 gatgcactgg tactcaacga caacggcggg cggagcattc actttgagcc gctgctgccg
     1261 ggggaggcgg tgtacagccg cagcgagtca atgtggctgg tgcgcggtgg taaggcagcg
     1321 cagccggacg gccacacgct ggcgcggctg tggggggcgc tgccgccgga tatccggtta
     1381 agcccgcatc tttacctggc gaccaacagc gcacaggggc cgtggtggat actggggtgg
     1441 tcagagcggg tgccgggtgc tgaggacgta ctgccagcgc cgctgccgcc gtaccgggtg
     1501 cttaccgggc tggcagaccg tttcgggcgg acgctgacgt accggcgtga ggccgcaggc
     1561 gacctggccg gggaaatcac cggcgtgacg gacggtgccg ggcgtgagtt ccgtctggta
     1621 ctgaccacac aggcacagcg ggcggaagag gcccgcacct cttcgctatc ttcttctgac
     1681 agttcccgcc ctctctcagc ctcaccgttc cccgacacac tgcccggtac cgaatacggc
     1741 cccgacaggg gcatccgtct ttcggcggtg tggctgatgc acgacccggc atacccggaa
     1801 agcctgcccg gtgcgccact ggcgcggtac acgtatacgg aagccggtga actgctggcg
     1861 gtatatgacc gcagcaatac gcaggtgcgc gctttcacgt atgacgcgca gcacccgggc
     1921 cggatggtgg cgcaccgtta cgcgggaagg ccggagatgc gctaccgcta cgacgatacc
     1981 gggcgggtgg tggagcagct gaacccggca ggcctgagtt accgctacca gtatgagcag
     2041 gaccgcatca ccgtcacgga cagcctgaac cggcgtgagg tgctgcatac agaaggcggg
     2101 gccgggctga agcgggtggt gaaaaaagaa ctggcggacg gcagcgtcac gcacagcggg
     2161 tatgacgcgg caggaaggct cacggcgcag acggacgcgg cgggacggcg gacagagtac
     2221 ggtctgaatg tggtgtccgg cgatatcacg gacatcacca caccggacgg gcgggagacg
     2281 aaattttact ataacgacgg gaaccagctg acggcggtgg tgtccccgga cgggctggag
     2341 agccgccggg aatatgatga accgggcagg ctggtatcgg agacatcgcg cagcggggag
     2401 acagtacgct accgctacga tgacgcgcac agtgagttac cggcgacgac aacggatgcg
     2461 acgggcagca cccggcagat gacgtggagc cgctacgggc agttgctggc gttcactgac
     2521 tgctcgggct accagacccg ctatgaatac gaccgcttcg gccagatgac ggcggttcac
     2581 cgcgaggaag gtatcagcct ttaccgccac tatgacaacc gtggccggtt aacctcggtg
     2641 aaagacgcac agggccgtga aacgcagtat gagtacaacg ccgcaggcga cctgactgcc
     2701 gttatcaccc cggacggcaa ccggagcgag acacagtacg atgcgtgggg aaaggcggtc
     2761 agcaccacgc agggcgggct gacgcgcagt atggagtacg atgctgccgg acgtgtcatc
     2821 agcctgacca acgagaacgg tagccataca gaatttagct gggatgtgct tgaccgcctg
     2881 atacagcagc gcggctttga cgggcggacg cagcgttacc gttatgacct gaccagaaaa
     2941 ctcac
//
LOCUS       DAZUDJ010000204         2849 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.209, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000204 DAZUDJ010000000
VERSION     DAZUDJ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2849
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.209"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            324..908
                     /locus_tag="ACHY1N_005185"
     CDS             324..908
                     /locus_tag="ACHY1N_005185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001310371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HFS4047301.1"
                     /translation="MAQELVTGLLSGQDYIKRNPDTEAMAKAQSIMNTWGYHKSNASI
                     GDAPLLFGGSVLGLTVKGMATNAAIGISVNSAAQLAGKDPFSYVDAIIAGVTAAATTG
                     KGIIVSTPINMSGAAIGSSIKGEDPTNSVIGTGLGSVFGGGIGKVISGSMGSTVKEGT
                     SDIIGNIGGSITGEAIGNVTKGTLDEVDKSIKNK"
     gene            970..1152
                     /locus_tag="ACHY1N_005186"
     CDS             970..1152
                     /locus_tag="ACHY1N_005186"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047302.1"
                     /translation="MAMLGTILGRLIVFSKTQVLFFDWRADIIYSLKVGGGAGMLAGI
                     GIWIKAKLQERKDDKK"
     gene            1416..1646
                     /locus_tag="ACHY1N_005187"
     CDS             1416..1646
                     /locus_tag="ACHY1N_005187"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047303.1"
                     /translation="MSHDAEKKIRLCIQCENEALKDSDFCAVCEEREFKKIRGWLYLP
                     AIGLVLTILANMISINFTIRFLMENIAQIGHA"
     gene            1653..1937
                     /locus_tag="ACHY1N_005188"
     CDS             1653..1937
                     /locus_tag="ACHY1N_005188"
                     /inference="COORDINATES: protein motif:HMM:NF022214.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HFS4047304.1"
                     /translation="MLFFELFAFIGMFSYGIFVSSLFFRKKRQLPHHYIALVGIGTIF
                     VAVDLLLGHIYLDVPYVFDTVKPLVRNVFSACIWIPYFIVSERVKRTFVK"
     gene            1972..>2849
                     /gene="cdiA4"
                     /locus_tag="ACHY1N_005189"
     CDS             1972..>2849
                     /gene="cdiA4"
                     /locus_tag="ACHY1N_005189"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000245723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDI system deoxyribonuclease CdiA-o11"
                     /protein_id="HFS4047305.1"
                     /translation="MVNATLSVVQKNSAFVGSATGELAARAIGMLYPGVKQSDLSEEQ
                     KQTISTLATVSAGLAGGLTGSSTASAAVGAQSGKNAVENNYLSTNQSLTFDKELSDCR
                     KSGGNCQDIIDKWEKISDEQSAEIDQKLKDNPLEAQVIDKEVAKGGYDMTQRPGWLGN
                     IGVEVMTSDEAKAYVQKWNGRDLTKIDVNSPEWTKFAVFASDPENQAMLVSGGLLVKD
                     ITKAAISFMSRNTATATVNASEVGMQWGQGNMKQGMPWEDYVGKSLPADARLPKNFKI
                     FDYYDGATKTATSVKS"
BASE COUNT          861 a          479 c          727 g          782 t
ORIGIN      
        1 ggggggctgc ttggtagtgg tttgtggttg ctagcaaaag tagagtttta ctttaaaaat
       61 aaaaaatagt tgttgagaat aactttctgg gagcgacatc ttctgacaaa ctggataaag
      121 ccattgagaa aatcaggaac ggcgataaga cattagccac tgctaatgag ctgattaagc
      181 tggaaaatgc agataaacgt agtgatgctc tggtatccaa atttaataaa gatccttcac
      241 aattaaacag cgcagaacgt gctgaactgg cagcttactt gcgtgtatat gcttcagaaa
      301 tggaaaagga gtacggtaca gcggtggcac aggagcttgt tactgggtta ctgtcaggac
      361 aggactatat aaaacgtaac cctgatactg aagcaatggc aaaggctcaa agcattatga
      421 atacctgggg gtatcataaa tctaatgcaa gtattggtga tgctcctttg ttgtttggag
      481 gaagcgtact ggggttaaca gtgaaaggta tggcgactaa tgcagcaatt ggtatcagcg
      541 taaactcagc tgctcagctt gctggaaaag atcctttcag ttatgtggat gcgataattg
      601 caggggtaac ggcagcagca acaacaggaa aaggaattat agtttcaacc cctatcaaca
      661 tgagcggcgc ggcaattggt agtagtatta aaggcgagga tccgacaaat tcagttattg
      721 ggacaggatt aggttcagta tttggtggcg gtatagggaa agtcatctcg gggtcaatgg
      781 gctctactgt caaagaggga acatctgata ttattggtaa tattggggga tcaattactg
      841 gtgaagctat cgggaatgta acaaaaggaa cactagatga agttgataaa tccattaaaa
      901 ataaataaga gtgtcaactt ttacattctt atcatactaa taacgcgctg catagcttgc
      961 atctttttta tggcaatgtt aggtacgatt cttggtagac tgatagtttt ttctaaaact
     1021 caagttttat tttttgattg gagggcggat attatttatt ctttaaaggt ggggggaggg
     1081 gctggtatgt tagcagggat tggtatttgg ataaaagcaa agttacaaga aagaaaagac
     1141 gataaaaaat aggcttacgg taacttcaac tttggggaat ttttattggt agttatgttc
     1201 ttggtcaatg ccatcaggaa tgaggtaatg tgcgtattac cgtggaagtg atcggtgagt
     1261 aactccaatc tcaatagagg ttattgggcg ctctccttcc atgaaaacac gcaacctaat
     1321 cggggaccgg ggcatatgct gactggtgac aatacagatg aaaataaaca gcatgatctt
     1381 caacttttcc cgtataaata ataggtgatt atcagatgag ccatgatgca gagaagaaaa
     1441 taagactttg tattcaatgt gagaatgaag cactgaagga cagtgacttt tgcgctgttt
     1501 gtgaagaacg cgaatttaaa aaaattcgtg gttggctata cttgcctgca ataggactgg
     1561 ttttaacaat tctcgctaat atgatctcta ttaatttcac tatacgattc ttaatggaaa
     1621 atattgcgca gatcggtcac gcataaaagg ggattctctt ttttgaactc tttgctttca
     1681 ttggtatgtt ttcctatgga attttcgtta gtagtttgtt ttttcgtaaa aagcgtcaat
     1741 tgcctcatca ctatattgca cttgttggga taggaacgat atttgtcgct gtcgatttac
     1801 tgctgggcca catctattta gacgtgcctt atgtttttga tacggtaaaa ccattggtac
     1861 gtaatgtgtt tagtgcctgt atttggatcc cctatttcat tgtatctgag cgcgttaagc
     1921 ggacatttgt gaaataattt gtccgtcaga tgtcccacat gaactcatgc agtggtgaat
     1981 gccacgctgt cggtggtaca gaaaaatagc gcctttgtcg gctcagcaac aggagaactg
     2041 gcagccagag cgatcggaat gctgtatccg ggcgtgaaac agtcagacct cagtgaagag
     2101 cagaagcaga cgataagtac gctggcaacc gtgtcagcag ggctggccgg cggtcttacc
     2161 ggaagcagca ccgcatcagc agcagtggga gcacagagcg ggaagaatgc tgttgagaat
     2221 aattacctta gcacaaacca gtctctgacc ttcgataaag aattgtctga ttgtcggaaa
     2281 tctggaggta actgccagga cattattgat aaatgggaaa aaatcagtga tgaacagagt
     2341 gcagaaatcg atcagaagct gaaagacaat ccgctggaag cccaggttat tgataaggaa
     2401 gttgcgaagg gcggatatga tatgacgcag cgcccaggtt ggctgggtaa cattggtgtg
     2461 gaagtaatga ccagtgatga agccaaagcc tatgttcaga agtggaatgg acgggatctg
     2521 acaaaaatag atgtaaacag ccctgaatgg actaagtttg cagtgtttgc ttctgatcct
     2581 gaaaatcagg ccatgctggt cagcggaggt ttgctggtaa aagatataac taaagcggct
     2641 atatcattca tgagtcgcaa tacagcgaca gcgacggtca acgcatcaga agttggaatg
     2701 cagtggggac agggaaatat gaaacagggt atgccgtggg aggattatgt tgggaaatct
     2761 cttcccgctg atgcccgttt accaaagaac tttaagatct ttgattacta tgatggtgct
     2821 accaaaactg ctaccagtgt aaaatcaat
//
LOCUS       DAZUDJ010000205         2845 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.210, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000205 DAZUDJ010000000
VERSION     DAZUDJ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2845
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.210"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            468..683
                     /locus_tag="ACHY1N_005190"
     CDS             468..683
                     /locus_tag="ACHY1N_005190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0020002 - host cell plasma membrane
                     [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA];
                     GO_process: GO:0019835 - cytolysis [Evidence IEA];
                     GO_process: GO:0044659 - viral release from host cell by
                     cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II holin family protein"
                     /protein_id="HFS4047306.1"
                     /translation="MHQMEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGS
                     LLFGLLTYLTNLYFKIKEDKRKAARGE"
     gene            683..1180
                     /gene="rrrD"
                     /locus_tag="ACHY1N_005191"
     CDS             683..1180
                     /gene="rrrD"
                     /locus_tag="ACHY1N_005191"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme RrrD"
                     /protein_id="HFS4047307.1"
                     /translation="MSPSLRKAVAAAIGGGAVAIASVLITGPGGNDGLEGVSYIPYKD
                     IVGVWTVCHGHTGKDIMPGKTYTEAECKALLNKDLATVARQINPYINVDIPETTRGAL
                     YSFVYNVGAGNFRTSTLLRKINQGDIKSACDQLRRWTYAGGKQWKGLMTRREIEREVC
                     LWGQQ"
     gene            1177..1614
                     /locus_tag="ACHY1N_005192"
     CDS             1177..1614
                     /locus_tag="ACHY1N_005192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009453323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HFS4047308.1"
                     /translation="MSRVTAIIYVLVICLIVCLSWAVNHYRDNAIAYKEQRDKATSII
                     ADMQKRQRDVAELDARYTKELADANATIESLRADVSAGRKRLQVSATCAKSTTGASSM
                     GDGESPGLTADAELNYYRLRGGIDRITAQVNYLQEYIRTQCLK"
     gene            1764..2381
                     /locus_tag="ACHY1N_005193"
     CDS             1764..2381
                     /locus_tag="ACHY1N_005193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HFS4047309.1"
                     /translation="MLASLGGLVSCAAKVHFKEAGNAMNELIANHDFDFRQLVTAAEG
                     QPVTDTFQIARAFGKRHQHVIRAIKCLRCSEEFSTTHFWAVEKINDLGIFDKKQIYYR
                     MDFSGFVMLVMGFNGAKADAVKEAYINAFNWMSAELRKYSESYEAERNAIMLEYMKEK
                     DVASMSGRLLNRWGRTKKPQLLAKLERLERQGQFLLPGFDKGIQA"
     gene            complement(2569..2763)
                     /locus_tag="ACHY1N_005194"
     CDS             complement(2569..2763)
                     /locus_tag="ACHY1N_005194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001307652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HFS4047310.1"
                     /translation="MSTKNRTRRTTTRNIRFPNQMIEQINIALEQKGSGNFSAWVIEA
                     CRRRLTSEKRAYTSIQSDDG"
BASE COUNT          756 a          620 c          734 g          735 t
ORIGIN      
        1 tgctggagat aaatgcaccg gcagcataat aaaaaaagcc agcgactgac ctgaaaaaga
       61 agacgctggc taaaaggcct tatatgtttg tagagactta tttttcacag acagcaatga
      121 tgcctgtcaa tatattatca atatgcggat tgtttcagtt acagatgcct tattaaggaa
      181 aaaaacagcc agcactgact ttcggtggag aggtgctggc tcaaaaggat agatgtactt
      241 cacatgttgc ttctatatgg cagtacattt tctgacagac agtgacggat gttgtcaaga
      301 tattgtgtca tttataacct gaatcagggg aggccggaat gttatctggc atttttagca
      361 gagcctgaat gccataatca cggctcccgg cgttggccgt cagtgggtga cactggcggc
      421 ttttttgttt ttctttactt tcattttctg tcggcggtga cggagacata catcagatgg
      481 aaaaaatcac aacaggtgtg tcatacacca cgtcagcggt ggggacggga tactggttac
      541 tgcagctgct ggacaaagtc tctccgtccc agtgggtggc aataggtgtg ctgggaagtc
      601 tgctgtttgg cctgctgacg tatctgacaa atctttattt caagattaaa gaagataagc
      661 gtaaggctgc gagaggtgaa taatgtcgcc gtcattacgc aaggctgttg cagctgctat
      721 tggtggtggg gctgttgcca tagcgtctgt gctcatcact ggtccaggtg gtaacgatgg
      781 tctggaaggt gtcagctaca taccatacaa agatatcgtt ggcgtatgga ctgtatgtca
      841 cggacacacc ggaaaagaca tcatgcccgg taaaacgtat accgaagcag aatgcaaagc
      901 cctcctgaat aaagaccttg ccacggtcgc cagacaaatt aacccgtaca tcaacgtcga
      961 tataccggaa acaacgcgcg gcgctcttta ctcgttcgtt tacaacgtgg gcgctggcaa
     1021 tttcagaaca tcgacgcttc ttcgcaaaat aaaccagggc gatatcaaaa gcgcatgtga
     1081 tcagctacgg cgctggacat acgctggcgg taagcaatgg aaagggctga tgactcgccg
     1141 tgagattgag cgtgaagtct gtttgtgggg gcaacaatga gcagagtaac cgcgattatc
     1201 tacgttctgg tcatctgcct catcgtctgc ctttcatggg ctgttaatca ttaccgtgat
     1261 aacgccatcg cctacaaaga gcagcgcgat aaagccacat ccatcatcgc tgatatgcag
     1321 aagcggcaac gtgatgtagc agaacttgac gccagataca caaaggagct tgctgatgct
     1381 aatgcgacta tcgaaagtct ccgtgctgat gtttctgctg ggcgtaagcg cctgcaagtc
     1441 tccgccacct gtgcaaagtc aacgaccgga gccagcagca tgggcgatgg agaaagccca
     1501 ggacttacag cagatgctga actcaattat taccgtctcc gaggtggaat cgacaggata
     1561 accgcgcagg ttaactacct gcaggaatac atcaggacgc agtgcttaaa ataattttaa
     1621 tttcactgaa atttaacaag tgactttcag gaaaatgcct cgcagatgcg gggcattttt
     1681 gtaccggtat ttcaccgcgc accgcagcgc acaataaaca ccgaacctga ccctttggaa
     1741 tgggcctttg aggataccag ttagtgctgg cgagcctcgg tgggctggtt tcctgtgcgg
     1801 caaaggttca tttcaaagaa gcaggcaacg ccatgaatga attaattgcg aatcatgact
     1861 tcgactttcg ccagttagtt accgcagcag aaggtcaacc ggtaactgac accttccaga
     1921 ttgccagggc atttggtaaa cgccatcagc atgtgattag ggctattaaa tgtttgagat
     1981 gttctgagga attctcgaca acccattttt gggccgtcga gaaaatcaat gacttaggga
     2041 tttttgacaa gaaacagatt tactaccgca tggactttag tggcttcgtt atgctggtta
     2101 tgggatttaa cggggcaaaa gccgatgctg ttaaagaagc ctatatcaat gcgtttaact
     2161 ggatgtcagc agaactccgt aagtacagcg aaagttatga agcagaacgc aacgccataa
     2221 tgctggagta tatgaaagag aaggatgtcg ccagcatgtc aggccgtctg ctcaatcgct
     2281 gggggagaac gaaaaaacct caattgcttg caaagctgga acgtctggag agacagggac
     2341 agtttttatt accgggattc gataaaggta ttcaagcctg acacattatg cgctgtatcg
     2401 tcgccgtatt cccgcattaa ccatgaccgt agcccgacgg ggaattcctt ctgcgtgagt
     2461 gtgcgggaat aatcaaaaac gatgcacacc gggttttact gtgctgacag acgcagggtt
     2521 accctcatag tcgcttttcc ggtgcgatgg tggaagaaac cgggatgttc atccatcatc
     2581 actttggatt gatgtatatg ctctcttttc tgacgttagt ctccgacggc aggcttcaat
     2641 gacccaggct gagaaattcc cggacccttt ttgctcaaga gcgatgttaa tttgttcaat
     2701 catctggttt ggaaatcgga tgttgcgggt tgttgttctg cgggttctgt tcttcgttga
     2761 catgaggttg ccccgtattc agtgtcgctg atttgtattg tctgaagttg tttttacgtt
     2821 aagttgatgc agatcaatta atacg
//
LOCUS       DAZUDJ010000206         2843 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.211, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000206 DAZUDJ010000000
VERSION     DAZUDJ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2843
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.211"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1497
                     /gene="escC"
                     /locus_tag="ACHY1N_005195"
     CDS             <1..1497
                     /gene="escC"
                     /locus_tag="ACHY1N_005195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE outer membrane
                     ring protein EscC"
                     /protein_id="HFS4047311.1"
                     /translation="CSAQAAPSSLEKRLGKNEYFIITKSSPVRAILNDFAANYSIPVF
                     ISNSVNDDFSGEIKNEKPMKVLEKLSRLYHLTWYYDENILYIYKTNEISRSIITPTYL
                     DIDSLLKYLRDTISVNKNSCNVRKITTFNSIEVRGVPECIKYITSLSESLDKEAQSKA
                     KNKDVVRVFKLNYASATDITYKYRDQNVVVPGVVSILKTMASNGSLPSTGKGAVERNG
                     NLFDNSVKISADPRLNAVVVKDREITMDIYRQLISELDIEQRQIEISVSIIDVDANDL
                     QQLGVNWSGTLNAGQGSIAFNSSTAQANLSSSVISNANNFMIRVNALQQNSKAKILSQ
                     PSIITLNNMQAILDKNVTFYTKVSGEKVASLESITSGTLLRVTPRILDDNSNSLTGKR
                     RERVRLLLDIQDGNQSTNQSNAQDASSILPEVQNSEMTTEATLSAGESLLLGGFIQDK
                     ESSSKDGIPLLSDIPVIGNLFSSTTKQKHSVVRLFLIKATPIKSASSE"
     gene            1511..1966
                     /gene="cesD"
                     /locus_tag="ACHY1N_005196"
     CDS             1511..1966
                     /gene="cesD"
                     /locus_tag="ACHY1N_005196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SycD/LcrH family type III secretion system
                     chaperone CesD"
                     /protein_id="HFS4047312.1"
                     /translation="MSRKFSSLQDIYDFYQDGGTLASLTNLTQQDLNDLHSYAYTAYQ
                     SGDVITARNLFHLLTYLEHWNYDYTLSLGLCHQRLSNHEDAQLCFARCATLVMQDPRA
                     SYYSGISYLLVGNRKMAKKAFKACLMWCNEQEKYATYKENIKKLLGNTD"
     gene            complement(2352..2765)
                     /gene="grlA"
                     /locus_tag="ACHY1N_005197"
     CDS             complement(2352..2765)
                     /gene="grlA"
                     /locus_tag="ACHY1N_005197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE transcriptional
                     regulator GrlA"
                     /protein_id="HFS4047313.1"
                     /translation="MESKNKNGDYVIPDSVKNYDGEPLYILVSLWCKLQEKWISRNDI
                     AEAFGINLRRASFIITYISRRKEKISFRVRYVSYGNLHYKRLEIFIYDVNLEAVPIES
                     PVSTGPKRKNYRVGNGIVGQSNIWNEMIMRRKKEN"
BASE COUNT          945 a          546 c          509 g          843 t
ORIGIN      
        1 tgcagtgctc aggctgcccc gtcctctctg gaaaaaagat taggcaagaa cgagtatttt
       61 attattacaa aaagctctcc ggtacgtgca atcctcaatg attttgccgc taattatagc
      121 atccctgttt tcatcagtaa ttctgtgaat gatgatttct ctggtgaaat aaaaaatgaa
      181 aaaccaatga aagtactgga aaaactgtcc aggctctatc atctcacatg gtattatgat
      241 gagaacattt tgtatattta taaaacaaat gaaatatcaa gaagcataat tacgccaaca
      301 tatctggata ttgactcact gttaaaatat ctgcgtgata caatctcagt aaataaaaac
      361 tcctgtaacg tgagaaaaat cacaacattt aactcgattg aagttcgtgg cgttcctgaa
      421 tgcataaaat acattacatc tttatctgaa agtcttgata aagaagcaca gtctaaagca
      481 aaaaataaag atgtcgttag agtatttaaa ttaaactatg catcagcgac agatataacg
      541 tataaatacc gcgaccaaaa tgttgtcgtg cctggcgtcg tctccatcct gaagacgatg
      601 gcaagtaatg gctcacttcc cagcacaggc aaaggtgctg tagaaagaaa cggcaacctg
      661 tttgataaca gtgtaaagat ttccgcagat ccacgtctta atgcagttgt tgtaaaagat
      721 cgtgaaataa ctatggacat atatcggcaa ttaatttctg agcttgatat tgagcaaagg
      781 caaattgaga tttctgtttc aattattgat gttgatgcaa atgatcttca gcaactggga
      841 gtaaactggt ccggtacatt aaatgcaggg caaggttcta ttgcctttaa cagctcaacg
      901 gcgcaagcta atctcagttc ttctgtgata agcaacgcca ataatttcat gatcagagtg
      961 aatgcgttac aacagaactc gaaagcaaaa atactctctc agccatcaat tataacctta
     1021 aataatatgc aggcgattct tgataaaaac gtaacgtttt atacaaaagt ttccggagaa
     1081 aaggtggcat ctctggaaag tattaccagc ggaacattac tgagagtgac accacgtata
     1141 cttgatgaca actcgaatag tcttaccgga aaacgtcggg aacgagttcg tttgttactt
     1201 gatattcagg atggcaatca atcgactaac caaagtaatg ctcaggatgc cagcagcatc
     1261 ttacctgaag tacaaaattc agaaatgaca acagaagcga cattaagcgc tggagaaagt
     1321 ctgctgcttg gcggatttat ccaggataaa gagagttcaa gtaaagatgg tataccgttg
     1381 ttaagtgata ttcctgttat tggtaactta ttctccagta caacaaaaca aaaacacagc
     1441 gttgttcgac tctttttgat taaagcgacc ccgataaaat cagcatctag cgaataataa
     1501 atgaggcttt atgagcagga aatttagctc tctacaggat atctatgatt tctaccagga
     1561 tggtggtacg ttagcatcac tgacaaattt gacgcaacaa gatctcaatg atcttcattc
     1621 ttatgcctat acagcatatc aatctggtga tgttataacc gcaagaaatc tatttcatct
     1681 gctaacatat ctggagcact ggaattatga ctacacccta tctctggggt tgtgtcatca
     1741 gcgtttatca aatcatgaag atgcacaact gtgtttcgct cgctgtgcaa ctttagttat
     1801 gcaagatccc agggcatctt attattctgg gattagctac ttattggtcg gaaatcggaa
     1861 aatggccaaa aaagccttta aggcttgttt aatgtggtgt aatgaacaag aaaaatacgc
     1921 tacatataaa gaaaatatta aaaaattgtt aggtaataca gattaaaaac taccatctgc
     1981 cataccaatc cccaggctgt ctggggattt tctatcggaa ataataaagc tgctttggtg
     2041 aagtgcgccc aacgttgagc accgaccgct gacagattta tctacaggag tgggttactc
     2101 cattaaccag gattttatgc gcctgaacca tcttctgctg tactcaatgt catttccgct
     2161 tatagaataa gcagtatata tcttaactta gcatcagaaa tctgactgtt tcaatcatct
     2221 atagcccaga gtgtatttgt caggaaatga ctttcaaact ttggcagaga aaaaggctta
     2281 tcctggaaaa caaagccctt gaatagagct ttatttttat tcttctataa aatatactca
     2341 aaaaaatacg tttaattctc ctttttccgc ctcatgatca tttcgttcca gatattagac
     2401 tgccccacaa taccattacc gactcggtag ttttttcttt ttggtccggt tgataccgga
     2461 ctttctatcg gaacagcctc gaggttaaca tcataaatga aaatctcaag gcgcttataa
     2521 tgcaagttac cataactaac atatctgaca cgaaatgaaa ttttttcttt tcttctcgat
     2581 atataagtta taataaatga tgctctcctc aggtttatac cgaatgcttc ggcaatatca
     2641 ttgcgagaaa tccatttctc ctgcaattta caccaaagag aaaccaagat atacagaggc
     2701 tcaccatcgt aattctttac tgagtcagga attacatagt cgccattttt atttttagat
     2761 tccattttcc atgttctttt tatttgataa ataaatcgac ataaaaacat tcataaacaa
     2821 aaaattattt taaataaaac tta
//
LOCUS       DAZUDJ010000207         2830 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.212, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000207 DAZUDJ010000000
VERSION     DAZUDJ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2830
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.212"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..109)
                     /locus_tag="ACHY1N_005198"
     CDS             complement(<1..109)
                     /locus_tag="ACHY1N_005198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HFS4047314.1"
                     /translation="MKNIAAAGVLERIRRLAPQASVPPYRTVEEWREWQL"
     gene            complement(116..1198)
                     /locus_tag="ACHY1N_005199"
     CDS             complement(116..1198)
                     /locus_tag="ACHY1N_005199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001736248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HFS4047315.1"
                     /translation="MANAWLRLWHDMPNDPKWRTIARVSGQPIATVMAVYIHLLVSAS
                     RNVTRGHIDVTTEDLASALDVTEEVIDSILQTMQGRVLDGDLITGWEKRQVLKEDNGN
                     ISQTAKSPAERKRAQRERERKREQNGDCHGASRNVTHMSRRVTTDKDTDKDTDKDTDQ
                     EDQNTMVHGVKNATNQAGDVQTVNPGQPAGTTPEADSAYALKADSGAVQQVMTARPEQ
                     SHQLQQPEADSAIQREADRVVPENTGQPVGRVDYPDVFEQVWREYPLRAGANPKKSAF
                     SAWKARLREGVPPEAILDGVRRYARYLAATGKTGTEFVQRATTFFGPDRNFENPWLLP
                     VSGTNNQRCVNHISEPDTEIPPGFRG"
     gene            complement(1270..1695)
                     /locus_tag="ACHY1N_005200"
     CDS             complement(1270..1695)
                     /locus_tag="ACHY1N_005200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin YdaT family protein"
                     /protein_id="HFS4047316.1"
                     /translation="MKIKHEHIRMAMNAWARPDGEKVPAAGITQAYFELGMTFPELYD
                     DSHPEALARNTQKIFRWVEKDTPDAVEKIQALLPAIEKAMPPLLVARMRSHSSAYFRE
                     LVETRERLVRDADDFVAVAIAGFNQMNRGGPAGNAVAVH"
     gene            complement(1679..1921)
                     /locus_tag="ACHY1N_005201"
     CDS             complement(1679..1921)
                     /locus_tag="ACHY1N_005201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/CI family transcriptional regulator"
                     /protein_id="HFS4047317.1"
                     /translation="MKKSEVLGYFGGVVKTAAALGTSKTTVSMWGEEVPWKWALLIQA
                     VTAGALKYELHIPTVVIPGSDHNPPSNQGGIHENQA"
     gene            2313..2651
                     /locus_tag="ACHY1N_005202"
     CDS             2313..2651
                     /locus_tag="ACHY1N_005202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310236.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HFS4047318.1"
                     /translation="MKNSSITSCVQLVGEIPANTFAVVLESDSMSTSGGGVSIPNGST
                     VFVDPNRTVQPGNIVLALPKGTTTPVIRKLEIEGPDILLVPTNPRYPSIMLDDLSCIL
                     GVCFKIQQDI"
BASE COUNT          668 a          779 c          618 g          765 t
ORIGIN      
        1 caagttgcca ttcccgccac tcctccaccg tccggtacgg tggaaccgac gcctgtggtg
       61 caagtctgcg aatacgttca agaaccccgg ctgccgcaat gtttttcatg ccacatcacc
      121 ccctgaatcc cggcggaatt tcggtatccg gttcagaaat atgattcaca caacgctggt
      181 tgttcgtgcc gcttaccggg agcaaccagg ggttttcaaa attccggtcc ggcccaaaaa
      241 acgtcgtcgc tcgctgaaca aattccgttc ccgttttccc ggtagccgcc aggtatcttg
      301 cgtaacgcct cacaccatcc agtatggcct ctggtggcac cccctcgcgt aatctggcct
      361 tccaggcact gaaagcggat ttcttcgggt ttgccccagc acgcaacggg tattcccgcc
      421 agacctgttc gaacacatcc ggataatcca ctcgtcccac aggctgcccg gtgttttccg
      481 ggactacccg atcggcttcc cgctgaatgg cggaatcggc ttcaggctgc tgcagttggt
      541 gtgattgctc cggccttgcg gtcatcacct gctgcacagc gcccgaatcg gctttcagcg
      601 catacgctga atcggcttcc ggtgtcgtgc ctgctggctg accaggattg acggtctgaa
      661 catcccctgc ctggttcgtg gcgtttttta cgccatggac catagtgttt tgatcttctt
      721 gatctgtatc tttatctgta tctttatctg tatctttatc tgtcgtgact cgtcgtgaca
      781 tgtgcgtgac atttcgtgac gcgccgtgac aatcgccatt ttgttcccgc tttctttccc
      841 tctctcgctg cgccctcttg cgctctgcag gagattttgc ggtttgcgaa atattgccgt
      901 tgtcctcttt aagcacctgg cgtttttccc atccagtgat taaatcacca tcaagtaccc
      961 gcccctgcat cgtctgcaaa attgaatcaa ttacctcttc tgtcacgtcg agcgcacttg
     1021 ccaaatcttc tgtcgtgaca tcaatgtgac ctcgcgtgac atttcgtgac gcgctcacca
     1081 ggaggtggat atacactgcc atcactgttg caattggctg ccctgacacc ctggcaattg
     1141 ttcgccactt agggtcattt ggcatgtcat gccataatct gagccaggcg ttagccatac
     1201 tcacctcttc tgataccgaa tctttttact cacgagttgc cggaagcgat tcgatacggc
     1261 tattgtcagt caatgtactg ccacagcatt tcctgccggg ccaccacggt tcatctgatt
     1321 gaaaccggcg attgccactg cgacaaaatc atcagcgtct ctcaccagtc gctcccgcgt
     1381 ctccaccagc tcccgaaaat aagctgaact gtggctgcgc attctggcca ccagcaaagg
     1441 tggcattgcc ttttcgatcg ctggtaacaa cgcctgaatt ttttcaactg catcaggggt
     1501 gtctttctct acccagcgga aaattttctg ggtattgcga gccagggctt ccggatggct
     1561 gtcgtcatac agttcaggaa acgtcatacc caactcaaaa taagcctggg ttattccagc
     1621 tgccggaact ttttcgccat caggacgcgc ccaggcattc atcgccatgc ggatgtgttc
     1681 atgcttgatt ttcatgaatc cccccttggt tagaaggcgg attatgatca gaaccgggaa
     1741 tgacaaccgt cggtatgtgt aactcatatt tgagcgcccc ggcagtgact gcctgaatta
     1801 gcaacgccca tttccacgga acctcttccc cccacatgct gactgtggtt tttgacgttc
     1861 ctagagctgc ggctgtttta acaactccgc caaaatagcc taatacttct gattttttca
     1921 tgagtcgctc cataaaactg aacgccaaaa gtttaataat caaaaccaaa gaaagtcaag
     1981 aaacaaaacc atctgtgttt taaaatcaaa acatgagcaa gcaaacaata tctgaacgca
     2041 taacccaacg tatgcatgcg ctaaacctga aaggcaaaga ccttgtcaat gccactggcg
     2101 catcaaaagg ctccgtaagt caatggatga acggtggagg agcgccgtcc tcgcgttaca
     2161 taagttcact ggcaaaaata ttgaaagtaa acgaaaattg gcttcttaat ggaggagagt
     2221 taaatacagg tgattcgctt gatctatctt taccgccgat aaaaacggtt ccgctactat
     2281 cacttcagca ggcagcaagc tggagtgatt atatgaaaaa ttcctcaata acctcttgtg
     2341 tgcagcttgt cggagaaatc ccggccaata cctttgcagt tgttctagag agtgacagta
     2401 tgtcaacatc tggtggggga gtttccatcc caaatggttc aacagttttt gttgatccca
     2461 atcgaaccgt acaaccagga aatattgtcc ttgccttacc caaagggacc acaacacctg
     2521 tcattcgtaa actggagata gaagggccgg atattctttt agtccccacg aatcctcgct
     2581 acccttcaat tatgctggat gatctatctt gcatattggg cgtatgcttt aaaattcaac
     2641 aagatattta accgacctca tctatttgat taactgtatg ccatcgtggt gatggcttaa
     2701 cagctgcctg cttaaaatgt tttgataaaa aaacattgac ctgaaaagtt catttttcta
     2761 aacttcattc attccctctc cccaccccac agaatgcagg gcaatacttc gagttaccag
     2821 gcagtggtca
//
LOCUS       DAZUDJ010000208         2746 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.213, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000208 DAZUDJ010000000
VERSION     DAZUDJ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2746
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.213"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..193)
                     /locus_tag="ACHY1N_005203"
     CDS             complement(<1..193)
                     /locus_tag="ACHY1N_005203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion apparatus protein OrgA/MxiK"
                     /protein_id="HFS4047319.1"
                     /translation="MNLALRKIIYDPISYIHPQRVSLNNTPINNPVLRSITNEMIVLQ
                     YNLSVEHFNLNSSLIYYINN"
     gene            complement(209..943)
                     /locus_tag="ACHY1N_005204"
                     /pseudo
     CDS             complement(209..943)
                     /locus_tag="ACHY1N_005204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311743.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EscJ/YscJ/HrcJ family type III secretion inner
                     membrane ring protein"
     gene            complement(940..1271)
                     /gene="sctI"
                     /locus_tag="ACHY1N_005205"
                     /pseudo
     CDS             complement(940..1271)
                     /gene="sctI"
                     /locus_tag="ACHY1N_005205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311744.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner rod subunit
                     SctI"
     gene            complement(1291..1531)
                     /locus_tag="ACHY1N_005206"
                     /pseudo
     CDS             complement(1291..1531)
                     /locus_tag="ACHY1N_005206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311745.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system needle complex
                     protein"
     gene            complement(1545..2727)
                     /locus_tag="ACHY1N_005207"
                     /pseudo
     CDS             complement(1545..2727)
                     /locus_tag="ACHY1N_005207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001365813.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0030257 - type III protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0030254 - protein secretion by the type III
                     secretion system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrgH/EprH family type III secretion apparatus
                     protein"
BASE COUNT          855 a          525 c          431 g          935 t
ORIGIN      
        1 aattgtttat gtagtaaata agtgaactat tcagattaaa atgttcaact gaaagattgt
       61 actgcagaac aatcatttca ttggtaatag atctaagcac cggattgtta ataggtgtat
      121 tattcaagct tactcgttga ggatgaatat aactaattgg atcatatata atctttctta
      181 gggcaagatt cataacgctc tcatatgtct acttaatttt caacctgact aaattagtta
      241 gaatggccct atacttccat aacagccagc aagtcgctac ggatattaat gcaagtaaga
      301 tagaaaccgg catagcctta tcataagcaa aaacaggttc gctaatttca tatgttggtg
      361 cttgctcaat aatgtctctt cgttttgaca atacaacaga aatattttca tattgtacgc
      421 ttgcagagct attaacaata aatctcttga tatcatttat ttttatttct gggttgatat
      481 ctttttcata tactgcaagt acagaaatat gaattggtaa agcagtttta ccactatcgc
      541 cattatcaac atcgtaacta acatgtactc tcgaagaaat aatgccatcc ataattttga
      601 gagattgctc taaccgctgc tcaatagcag aatatagcct tgctttttcc gctcgtggag
      661 atgaaacgag tgcatctgca gggaacatct gcgatatttg aatatcaggc ttacccggta
      721 gattgtagat ttttagccaa tccaccgcag aagcaaaatc cgttggttcg acaaatattg
      781 aaaatcctgt tttgccttaa tccttctttt cagcattaat attatgtctt tgtaaaacag
      841 caaggacatc attagcttgc tgttgatcaa gatggttcaa taattcctgc tgcttgcagc
      901 cgcacaacag caggataaac aataataatg atatatattt catgagcggg tcaacgtctc
      961 aactgcagcg acaatctttc ttgctaatgt tccaccaatg aaacctcgac attataatta
     1021 agcacatgat cctgcaagac taataatttt tcaggagtta acccctcttt atcagacctt
     1081 aatgcttgta acgcattttg ctgccaattt tcagtttgta cagcatagtt ggcaaaagcg
     1141 gagatcattt tatcatccgg gttgtcaaga ttgagaaccc ggtcatttaa atcaatcact
     1201 ttcgcttgct gtatttcatg agcagttgat tgctcagctc tatcaatagg tggcatattg
     1261 cttactgaca taataaaatc cttatccagt ttagcggaag ttttgtatga ttgctgaatc
     1321 aagatcttta tacgctttta caacgttaga ttgcgcattt cgatataatg tatactcagc
     1381 taatgcactt tgatattcgg caagaaattt cgtgtcggag ggattggttg gctaaatcct
     1441 ccaacgcttt ttcaacttgc tggttcagat catcaacgcc ctgatcaaat tgattgctga
     1501 tatccataat ataaccattc caatctgcca taagtcctcc tcaattattc ctgaaatgtc
     1561 cagttgctac cttgagactt ctcgaatcgg ttatctccgt agctaaatga actattattt
     1621 gtgtcctgat ttttcaaatt cacattaaat cttacatatt gtttacccca ttgtttataa
     1681 tattcgtcaa catagttatt aattttattt aattcactgt cacttaacgt accaatgata
     1741 ttgaaataca cattgttagc tgttttatat ttttcataag aaagacctat cgctgacaac
     1801 gtttcaatag cctgactttc caatacatta tcatctaata ccgcaatact tatattgctg
     1861 gcatatggca tagtttgcag taatccttta ataagattat cgattagttg ctgtgtgata
     1921 gcgttccgtt gcttactcac tgtcaatctt agattactgg catctaatag ttgaagttta
     1981 aaatattgta aatcagggaa attatcagca agccatgaaa aaattcgtat cgattcatca
     2041 tcaggattta tcacccgtac tggctttcct ggttgatttt tttccagtgc ttgtttgacc
     2101 cagactgctt catccaaaat attggtatta atatagataa catgatctct accatataaa
     2161 acttcataat tcctgttttt gtttacaaga attttatcga tatgtctcag ctgcggatca
     2221 ttactagcat taacaatata aaaagcaata aaaatgatag caaaaagaaa aaaaaagcat
     2281 tacatactta aacagcttac tgctaaagaa atgttgtttt gtagaaataa tgttattttc
     2341 aataatgcct ggcaatgaat actgccaaac ttcatttttt tcttttacag caaatttgag
     2401 acctaaaact tctatttgct gattcaatgt taacgttcta tcttcaggtt cttgtgctgt
     2461 taattctctg aatgttacta ccagatcagg gtcggtagta attattatct caaaactacc
     2521 tgtaagctcg ccataaggaa cgactattgt gttttctggt aactcagaaa aagcatcact
     2581 tcttcctaac gaaacatcat taccaatgat aacaagtaga cgcccattaa gtatttcata
     2641 ctcgcatcca ttcaatggtc cgctcaacaa acgaatggca taagattcca ataagtcttg
     2701 tgataagaat ttatcattat tttccatgaa taccacccgc taattc
//
LOCUS       DAZUDJ010000209         2730 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.214, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000209 DAZUDJ010000000
VERSION     DAZUDJ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2730
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.214"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..128)
                     /locus_tag="ACHY1N_005208"
     CDS             complement(<1..128)
                     /locus_tag="ACHY1N_005208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4047320.1"
                     /translation="MIVLILVFRLVIGEQMIDVLGPEKRRRRTTQEKIAIVQQSFEP"
     gene            172..309
                     /locus_tag="ACHY1N_005209"
                     /pseudo
     CDS             172..309
                     /locus_tag="ACHY1N_005209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683609.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4014 family protein"
     gene            311..868
                     /locus_tag="ACHY1N_005210"
     CDS             311..868
                     /locus_tag="ACHY1N_005210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF551 domain-containing protein"
                     /protein_id="HFS4047321.1"
                     /translation="MSTITRERAEIKSYITGFLSDSAHDNKSSDSLLANVFRIALASL
                     EAEPIAMVVPDEMDLLTCHLDGVTKTYADGWNACRVAMLQAGNFRENKNSSTNNFREI
                     SETSTRSPITLDGWISCTERMPEKSQNVLISMNIDSEAGPLIYSARYLGGTFRRGGIA
                     VSPGNDLRQATHWMSLPEPPQEVNQ"
     gene            1159..1314
                     /locus_tag="ACHY1N_005211"
     CDS             1159..1314
                     /locus_tag="ACHY1N_005211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HFS4047322.1"
                     /translation="MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVF
                     VDYESEK"
     gene            1434..1778
                     /locus_tag="ACHY1N_005212"
     CDS             1434..1778
                     /locus_tag="ACHY1N_005212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiW/YdeI family stress tolerance OB fold
                     protein"
                     /protein_id="HFS4047323.1"
                     /translation="MKKVLIAALISGVSFGAFAQQGGFQGPEAERSTVAQAKELKDDA
                     WVILEGSIVKKVGDERYEFRDNSGTIVTDIDDSVWAGQNVSPKDKVRIEGEIDKDLSS
                     VEVDVKALKLLK"
     gene            1900..2172
                     /locus_tag="ACHY1N_005213"
     CDS             1900..2172
                     /locus_tag="ACHY1N_005213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047324.1"
                     /translation="MTQHIKSHNSEADPEIKQGRRFRAPQYGWFHYLFCTIDEADMLQ
                     EAYLRRGVRVERSLNADRLTWTVSVYLPVRAHLPRTHACYRQRVWR"
     gene            2174..>2730
                     /locus_tag="ACHY1N_005214"
     CDS             2174..>2730
                     /locus_tag="ACHY1N_005214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310222.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HFS4047325.1"
                     /translation="MRVLLRPVLVPELGLVVLKPGRESLPVFHRGRVLVEPEPKNMRA
                     LPSGAVPAVRQPLAEDKSLLPFFSDERVIRAAGGAGALSDWLLRHVKSCQWPHGDYHH
                     SETVIHSYGAGAMVLCWHCDNQLRDQTSESLEQLTQQNLTAWMIDVIRHVMNGTQERE
                     LSLAELSWWAVCNQVVDALPEAVSRR"
BASE COUNT          698 a          627 c          739 g          666 t
ORIGIN      
        1 ggttcaaagc tctgctgaac aattgcgatc ttttcctgtg tggtacgccg tctgcgtttc
       61 tccggcccta agacatcaat catctgttct ccaatgacta gtctaaaaac tagtattaag
      121 actatcactt atttaagtga tactggttgt ctggagattc agggggccag tctaataccg
      181 atatccccgc tattactggt ctggataatt ggaaggacat ttgaaccagt tattgagcta
      241 tataccgatg tgacatggga atcattcagc gcactgcaca ataaaattaa tccgtataag
      301 gaaaactgat atgagcacta ttaccagaga acgcgcggag attaaatcat acatcacagg
      361 cttcctgagc gactcggcgc acgataacaa gtcttcagac agcctgctgg ctaatgtgtt
      421 tcgtatcgcg ctggcatcac tggaagcaga gccgatagca atggtagtgc ctgatgaaat
      481 ggatttgctt acctgccatc tcgacggtgt aactaaaaca tatgctgatg gctggaacgc
      541 ctgccgcgtc gccatgcttc aggccggaaa ctttcgggaa aataagaatt cgtcaaccaa
      601 caattttcgg gaaatctcgg aaacgtcaac cagatctccg ataactctgg atggctggat
      661 aagctgtact gagcgaatgc ctgaaaagag ccagaacgtg cttatttcga tgaatatcga
      721 tagcgaggct gggccattaa tatattccgc acgctatctc ggaggcacgt tccggcgcgg
      781 aggtatagca gttagtccgg gtaatgatct taggcaagca acccactgga tgtcgctacc
      841 agaaccgccg caggaggtga atcaatgacc tggcctgaag cattcacaac ggtaggaatt
      901 gcgatggcgg tggcgctggt ggtgtattcg atttgccgct ggggataaaa acggtttgcg
      961 ggaaaaggat agttaagtag aattgcagcg ggtgcttgag gctatctgcc tcgggcatga
     1021 acaccaacgg cagatagaga aaagccccag ttaacattac gcgtcctgca agacgcttaa
     1081 cattaatctg aggctcaatc catgctgaac acatgtaggt tagcctctta cgtgccgaaa
     1141 ggcaaggaga agcaggctat gaagcagcaa aaggcgatgt taatcgccct gatcgtcatc
     1201 tgtttaaccg tcatagtgac ggcactggta acgaggaaag acctctgcga ggtgcgaatc
     1261 cgaaccggtc agacggaggt cgctgtcttc gtagactacg aatctgagaa gtaagagacc
     1321 aggcggggga gtaatctccc gccacctctg atgtgtcagg catcctcaac gcacccgcgc
     1381 tttaccatac tgaaaatgct gtttgaatgt tcatctctga aagaggacta tgaatgaaaa
     1441 aggtattgat tgcagcactt atttccggtg tgtcttttgg cgcttttgca cagcagggtg
     1501 gtttccaggg gccagaagca gagcgttcaa cagtagcgca ggcaaaagaa ctgaaggatg
     1561 atgcatgggt tatccttgaa gggagcatcg ttaaaaaagt gggtgatgaa cgttatgagt
     1621 ttcgtgacaa tagcgggaca attgtcacgg atattgatga cagcgtatgg gccgggcaga
     1681 atgtttctcc gaaagacaaa gtaagaattg agggtgaaat tgataaagac ctgagcagtg
     1741 ttgaagttga tgtaaaggca ctgaaattat taaagtaacc gcccctgctt gttaagcccg
     1801 tcttactgac gggttttctg tttgtacatt ccggcgtatt gccttacaat tcgcgcagtc
     1861 agcctgaaca actgacacct gctgtcaccg gagaatccga tgacacaaca cataaaatcc
     1921 cacaattctg aagccgaccc ggaaattaag caggggaggc gttttcgtgc gcctcagtat
     1981 ggctggtttc actatctgtt ctgtacgatc gatgaggcag atatgcttca agaggcgtat
     2041 ctgcgtcgcg gtgtccgtgt ggagcggagt ctgaacgctg atcgtctgac ctggaccgtt
     2101 tctgtatatc ttcctgttcg tgcacatctg ccacggacac atgcctgcta ccgtcagcgc
     2161 gtctggaggt aatgtgcggg tattacttcg acctgttctg gttccggaac tcgggctggt
     2221 ggtccttaag cccggtcgtg aatcattgcc agtttttcat cgcggcaggg tgctggtgga
     2281 gccggaaccg aaaaacatgc gggcgctgcc atctggagcg gttcctgctg ttcgccagcc
     2341 gctggcggaa gataaatcac tgctgccatt tttcagcgat gagcgggtga ttcgtgcagc
     2401 tggcggcgct ggtgcactgt ctgactggtt attacgtcac gtgaaatcct gccagtggcc
     2461 acacggcgat tatcatcaca gcgaaaccgt tattcacagt tacggtgctg gcgcaatggt
     2521 gttgtgctgg cactgcgaca accagctgcg cgaccagacc tccgaatcac ttgagcaact
     2581 tactcaacaa aatctgacag cctggatgat tgacgtcata cgccatgtaa tgaatggcac
     2641 gcaggagcgg gaattatcgc tggctgaatt atcctggtgg gcagtctgca atcaggtggt
     2701 ggacgcatta cctgaggcag tatcgcgtcg
//
LOCUS       DAZUDJ010000210         2718 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.215, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000210 DAZUDJ010000000
VERSION     DAZUDJ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2718
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.215"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            301..489
                     /gene="dicB"
                     /locus_tag="ACHY1N_005215"
     CDS             301..489
                     /gene="dicB"
                     /locus_tag="ACHY1N_005215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibition protein DicB"
                     /protein_id="HFS4047326.1"
                     /translation="METLLPNVNTSEGCFDIGVLLSNREFTEDAINMRKYEPYLLNDN
                     SILSRIALLELGIFGERQ"
     gene            486..674
                     /locus_tag="ACHY1N_005216"
     CDS             486..674
                     /locus_tag="ACHY1N_005216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1482 family protein"
                     /protein_id="HFS4047327.1"
                     /translation="MTSAFALMMTVFLITGESQNVITGIYASKESCLQARDEQKISGE
                     CLPVKKVSLYLNNETPAG"
     gene            767..>2718
                     /locus_tag="ACHY1N_005217"
     CDS             767..>2718
                     /locus_tag="ACHY1N_005217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051908 - double-stranded DNA 5'-3' DNA
                     exonuclease activity [Evidence IEA];
                     GO_process: GO:0090304 - nucleic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RecE family exodeoxyribonuclease"
                     /protein_id="HFS4047328.1"
                     /translation="MSTDKEEFALYCEAKNDKVRKRLGIKGGFYWTTAKKLSVAISRC
                     ITAMDDNDYDEDDFKKPVRVHLPVVNDLPPEGVFDTEFCNRYEKGGEDGITMVFIAPS
                     PSVQEKPASTDNTNVNGEDMTEIEENMLLPVSGQELPIRWLAQHGSEKPVTHVAREEL
                     QALHIARAEELPAVTALAISHNTKLLDPLEIRDLHKLARDTDKVFPNPGNSDLGLITA
                     FFEAYLDADYTDRGLLTKEWMKGNRVSRITRTASGANAGGGNKTDRNPNLVHTFDTLD
                     VEIAAATLPMDFNIYEIPGSVYRRAKEIVLKRESPFKEWSAALRATPGILDYSRAAIF
                     ALIRSAHPEFYHYPGRLQGYINAYLTETDHENPSKETLTAARHTPEKDILEEVNRELA
                     AKQETEEEENDEEKPQPSCAMADEQATAETVEPDATEHHQDTQPLDAQSQVNSVDAKY
                     QKLRAELHEARKNIPPQNPVDADKLLAASRGEFVEGISDPNDPKWIKGIQTRDSVYQN
                     QPETEQNDQKAEQNSPNTQQNEPETKQPEPVVQQEPEKICTACGQRSGGNCPDCGAVM
                     GDATYQETFDDKNLVEVQEDDSEKMEGAEHPHKENAGSAQDHASDSETGETADPLITV
                     NGHRIITSTSRTCDHLMIDLETMGKNP"
BASE COUNT          811 a          651 c          656 g          600 t
ORIGIN      
        1 ttgaggacac cgggttgtca ggttgaccat acgcttaagt gacaaccccg ctgcaacgcc
       61 ctctgttatc aattttctgg tgacgtttgg cggtatcagt tttactcctt ggctgctctg
      121 ccgccctttt taaagtgaat tttgtgatgc ggtgaatgcg gctcagcgca cgcggaacag
      181 ttaaaaccaa aaacagtgtt atgggtggat tctctgtatc cggcgttaat tgttaactgg
      241 ttaacgtcac ctggaggcac caggcaccgc atcacaaaat tcattgttga ggacgcgata
      301 atggaaacgt tattaccaaa cgttaatacg tctgaaggtt gttttgatat tggtgttctg
      361 ctcagtaacc gggagtttac tgaagatgcc attaatatga ggaaatatga gccttatctg
      421 ctcaatgata attccatact ttcccgaatt gctcttcttg aacttggtat tttcggagaa
      481 cgtcaatgac ttcagcattt gcactgatga tgacggtttt tcttataacg ggtgaatcac
      541 agaatgtgat taccggaatt tatgccagta aagaatcctg cctccaggca agagacgagc
      601 aaaaaatttc tggtgaatgc ctcccggtaa aaaaagtatc gctgtacctg aataacgaaa
      661 caccggctgg ataaccctcc agccatatta acaccatacc aacggattaa aaatgccagc
      721 aatggcaggg atttgttcac ccttaaatct gtaatgaggt ttatcaatga gcactgataa
      781 agaagaattt gcgctatatt gcgaagcaaa aaatgacaaa gtcagaaaac gtctgggaat
      841 taaaggtggt ttttactgga ctacagcaaa aaaattatct gttgccatct cccgctgcat
      901 taccgcaatg gatgacaacg attatgatga agacgacttt aaaaaacccg ttcgcgtcca
      961 tttacccgtt gtgaatgacc ttccacctga aggcgtgttt gataccgaat tctgcaaccg
     1021 atacgaaaaa ggcggggaag atggcattac aatggtattt atcgcgccct ctccctccgt
     1081 gcaggagaaa ccagccagta ctgacaatac caacgtcaac ggcgaagaca tgacggagat
     1141 tgaggagaat atgctcctgc cggtttctgg tcaggagctg cccattcgct ggcttgcgca
     1201 acacggcagc gaaaaaccag taacgcacgt tgcacgggaa gaacttcagg cattacatat
     1261 agcacgggcg gaagaactgc cggctgttac tgccctggcc atttcccaca acacaaagct
     1321 gctcgacccg ctggagattc gcgaccttca taaactggca cgcgacactg acaaagtttt
     1381 ccctaatccc ggtaattcag acctgggact gataactgct tttttcgagg catacctgga
     1441 cgctgactac actgatcggg gtctgctgac aaaagagtgg atgaaaggaa atcgtgtttc
     1501 gcgtatcacc cgtacggctt ccggtgcaaa tgccggtggc gggaacaaaa ccgatcgcaa
     1561 tccgaattta gtacacacct tcgatacgct ggatgtggag attgcagcag ccacacttcc
     1621 gatggatttt aatatttatg aaattccggg cagcgtttat cgtcgcgcaa aagaaatcgt
     1681 cctgaaaaga gaaagtccgt tcaaagaatg gtccgcagca cttcgcgcaa ccccgggtat
     1741 tctggactat tcccgcgccg ctatttttgc acttatccgg agcgctcacc ctgagtttta
     1801 tcactacccg ggacgccttc aggggtatat caacgcctac ttaacggaga ctgatcacga
     1861 gaaccccagc aaggaaactc tcactgctgc acgacataca ccggaaaaag atatcctgga
     1921 agaagttaac cgcgaactgg ctgctaagca ggaaacagaa gaagaagaaa atgatgaaga
     1981 aaaaccgcaa ccatcttgcg caatggcaga tgaacaggca acggctgaaa cagtggaacc
     2041 ggatgcaact gaacatcatc aggacacgca gccgctggat gctcagtcac aggtaaattc
     2101 tgttgatgcg aaatatcaga aactgcgggc agaactccat gaagcccgga aaaacattcc
     2161 gccccaaaat cctgtcgatg cagacaaatt actggctgcc tctcgcggag aatttgttga
     2221 agggattagc gacccgaatg atccgaaatg gattaagggg atccagaccc gcgattctgt
     2281 gtaccagaat cagccagaaa cggaacagaa cgaccagaaa gcggaacaga acagcccaaa
     2341 tacgcaacaa aacgagccag aaacgaaaca acctgaacca gtagtgcaac aggaaccgga
     2401 aaagatctgc accgcctgcg gtcagaggag tggcggcaac tgccctgatt gtggcgcggt
     2461 gatgggcgac gcaacatacc aggaaacatt cgatgacaag aacctggttg aagttcagga
     2521 agacgattcg gagaaaatgg aaggcgctga acatccacac aaggagaatg ctggcagcgc
     2581 tcaggaccac gccagcgata gtgaaactgg cgagacggca gatcccttaa ttacggtgaa
     2641 cggtcatcgc attatcacat ccaccagcag gacgtgtgac catctaatga tcgaccttga
     2701 aaccatggga aaaaatcc
//
LOCUS       DAZUDJ010000211         2713 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.216, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000211 DAZUDJ010000000
VERSION     DAZUDJ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2713
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.216"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            70..402
                     /locus_tag="ACHY1N_005218"
     CDS             70..402
                     /locus_tag="ACHY1N_005218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001163774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ClpX C4-type zinc finger protein"
                     /protein_id="HFS4047329.1"
                     /translation="MQHIDREKAQRLIERMEALAKEENVNIQKIAECGQIVLRREKDL
                     KQLMSGETSKTWTSGEKTVYCSFCNKSQYEVTKVIAGPSVYICNECVDLCNEIIRKEV
                     TDKKEKNA"
     gene            399..806
                     /locus_tag="ACHY1N_005219"
     CDS             399..806
                     /locus_tag="ACHY1N_005219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047330.1"
                     /translation="MNRKQKQELKYFLRKEIARLEDAESQSSEIPFGMDINDARMLQA
                     YRIAQAALQTKPLNNIHEKYDYFTDTACLLTSEEQKIAQLLGDAWNLYLTLPVEHPMG
                     RDEFCRAIHHCQNMVLARPAIRALARKGQGYKR"
     gene            complement(1291..2337)
                     /locus_tag="ACHY1N_005220"
     CDS             complement(1291..2337)
                     /locus_tag="ACHY1N_005220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001706445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4047331.1"
                     /translation="MSRKNKKVRMSSRIDLADALRKESSLSAFTFDGPYRLTGHDLLD
                     NMYCADNGRWYETPVDWYGLARAARQTSWHQSALYFKRNVLLGCYIPHPLLSRQDFSA
                     LALDWFVFGNAFLELRSNMLGEPLKLRHALAKYMRRGSDLESWWYVQDGKDAFQFRPG
                     KVCHLMNPDINQEIYGMPEYLGALLSASLSHSADMFRKLYYDNGSHAGCIIYIGAAQV
                     NRESMDSLKETLQGARGGGAFKNVLIHAPNGGKEGVQILPFQQITAKDEFMNVKAASR
                     DDVLAAHRVPPQLMGAMPGEKSAFGDVEKAARVYAINELMPVMEAMKHINDWLGEEVI
                     RFNPYALLDTQPTS"
     gene            complement(2337..>2713)
                     /locus_tag="ACHY1N_005221"
     CDS             complement(2337..>2713)
                     /locus_tag="ACHY1N_005221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="terminase-like family protein"
                     /protein_id="HFS4047332.1"
                     /translation="RYNVEHIGIDATGGHGDAVYQIVKRFFPAAIPYTFTLSSKRSLV
                     LKMLQIMRAGRWEYDRAERELVAAFNAVRKVKTPGGFITYETDRARGISHGDLAWATM
                     LAVINEPIGGEGENERFTVMEF"
BASE COUNT          733 a          684 c          684 g          612 t
ORIGIN      
        1 gaataataca acatcagggc gcatccgccc tgatgacttt aatccgggaa cacaaacaaa
       61 ggggacacaa tgcaacacat tgacagagaa aaagcgcagc gactgattga gcggatggaa
      121 gcgctggcga aagaagaaaa tgtcaacatc caaaaaatag ctgaatgtgg ccagatagtt
      181 cttcgtcgtg aaaaagacct caaacaactg atgtctggcg aaaccagcaa aacatggact
      241 tcaggcgaga agacggttta ttgcagtttc tgcaataaat cccagtacga agtcacaaag
      301 gtgattgccg gaccgtctgt ttacatctgc aatgaatgcg tggatttgtg caatgaaatt
      361 atcaggaaag aagtgacaga caaaaaggaa aaaaacgcat gaacagaaaa cagaaacaag
      421 agttgaaata cttcttacgt aaagaaattg ccaggcttga agatgcagag tcacaatcat
      481 cagaaattcc gttcggaatg gatatcaacg acgcccgtat gcttcaggca taccgtatag
      541 ctcaggctgc actacagaca aaaccgttaa ataacataca tgaaaagtat gattatttta
      601 cggataccgc ttgcttgctg acatcagaag aacaaaagat agcccaactt ttaggcgacg
      661 catggaacct gtatttaaca ttgccagttg agcatccaat gggtagagat gaattttgcc
      721 gggcaattca tcattgccaa aatatggtgt tggcacgccc ggccatcagg gcgttggcca
      781 ggaaggggca aggctataaa agataagtaa aacgccctcc tccagggcgt ttatttcaat
      841 gcacaatagt gcacaaattt gcacaatttt tttgaacgac tttttaccct tccggcccgc
      901 atggcggctg gatccgtcaa ggatccgtgc gtgcacaaaa aaacgcgctt tttctgcgcg
      961 caggtgacgg gggaacagcc cgcgtttcag ggggtaaata gcattccctg aacgatgtcg
     1021 cagagataca acagaatggc tgtatttctc acgctgagcg tgaaaaagac gtgagagctt
     1081 ttgatttgat ggggtgaaag gtaaggccgt caaaatcgca ctgagacggc gagaacatgc
     1141 agtcaacgcg gtgggattgc gtaagagtct gactgtcgat gatggcaatc agcaggaaag
     1201 cgtcgtgaaa ttatctgatt gatacaggag ctggagagtc ggggcataaa ttttttatgc
     1261 cccggcgaag cagcagacaa gcgaagcgcg tcaggatgtg ggctgggtgt ctaacagtgc
     1321 gtaagggtta aagcggatca cctcttcgcc aagccagtca ttgatgtgct tcatggcctc
     1381 catgacgggc atcagctcgt taattgcgta aacccgcgcg gccttctcca catcaccaaa
     1441 cgcacttttt tcgcccggca ttgcccccat cagttgcggc ggaacgcggt gcgcagccag
     1501 cacatcatca cgggatgccg ccttaacatt catgaactca tcctttgcgg tgatctgctg
     1561 gaacggcaaa atttgcaccc cctctttgcc cccgttgggc gcatgaatga gcacgttttt
     1621 aaacgcacca ccaccacgtg ccccctgtag cgtttctttc agggagtcca tgctttcgcg
     1681 gtttacctgc gctgcaccga tgtagatgat gcacccggcg tgggatccat tgtcgtaata
     1741 cagttttctg aacatgtccg ccgaatgaga caggctggcc gagagtaatg cgccaagata
     1801 ttccggcatg ccgtaaattt cctggttaat gtccggattc atcaggtggc acactttgcc
     1861 aggacgaaac tggaacgcgt ccttgccatc ctgcacatac caccatgatt caagatcgct
     1921 tccgcgtcgc atgtatttcg ccagggcgtg ccgtaattta agcggttcgc cgagcatatt
     1981 gcttcgaagc tcaaggaatg cgttaccgaa cacaaaccag tccagcgcca gcgccgagaa
     2041 atcctgccgg gaaagcagcg ggtgcggaat atagcagccg agcaatacat tgcgcttaaa
     2101 gtaaagcgca gactgatgcc aggacgtttg ccgggcagct cttgccagac cgtaccagtc
     2161 caccggggtt tcataccacc gcccgttatc agcacagtac atattgtcca gcaggtcatg
     2221 cccggtcagg cgataaggac catcaaatgt gaatgcactg agcgatgatt ctttcctgag
     2281 cgcatcagcg agatcaatgc gtgaactcat gcgcactttt ttattttttc tgctcatcag
     2341 aactccataa ccgtgaaacg ctcgttttct ccttcgccgc caatcggttc attaatgaca
     2401 gcaagcatgg ttgcccacgc aaggtcgccg tggctgatcc ccctcgctcg gtccgtttcg
     2461 taagtgataa agccgcccgg tgttttcacc ttacgcacgg cgttaaaggc cgcgaccagc
     2521 tcgcgttcgg cgcgatcgta ttcccaccgc ccggcacgca ttatttgcag cattttcagt
     2581 accagcgacc gttttgatga cagcgtgaag gtgtacggaa tagcagcagg gaaaaaccgt
     2641 ttcactatct gataaacggc atccccgtgc ccgccagtcg catcaatgcc gatgtgttcc
     2701 acgttgtagc gac
//
LOCUS       DAZUDJ010000212         2705 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.217, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000212 DAZUDJ010000000
VERSION     DAZUDJ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2705
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.217"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..459
                     /locus_tag="ACHY1N_005222"
     CDS             <1..459
                     /locus_tag="ACHY1N_005222"
                     /EC_number="3.1.11.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lambda exonuclease family protein"
                     /protein_id="HFS4047333.1"
                     /translation="AKALAWGKQYENDARALFEFTSGVNVTESPIIYRDESMRTACSP
                     DGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKDAWYFANYD
                     PRMKREGLHYVVVERDEKYMAGFDEMVPEFIEKMDEALAEIGFVFGEQWR"
     gene            456..638
                     /locus_tag="ACHY1N_005223"
     CDS             456..638
                     /locus_tag="ACHY1N_005223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1317 domain-containing protein"
                     /protein_id="HFS4047334.1"
                     /translation="MKHPHDNIRVGAITFVYSVTKRGWVFPDLSVIQNPLKAQRLAEE
                     INNKRGAVCTKHLLLS"
     gene            611..802
                     /locus_tag="ACHY1N_005224"
     CDS             611..802
                     /locus_tag="ACHY1N_005224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1382 family protein"
                     /protein_id="HFS4047335.1"
                     /translation="MHKASPVELRTSIEMAHSLAQIGVRFVPIPVETDEEFHTLATSL
                     SQKLEMMVAKAEADERDQV"
     gene            879..1094
                     /locus_tag="ACHY1N_005225"
     CDS             879..1094
                     /locus_tag="ACHY1N_005225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFS4047336.1"
                     /translation="MTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHR
                     ETVTLMGFTPTHLSLAIGMLNGVFKER"
     gene            1193..1414
                     /locus_tag="ACHY1N_005226"
     CDS             1193..1414
                     /locus_tag="ACHY1N_005226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HFS4047337.1"
                     /translation="MADIIDSASEIEELQRNTAIKMRRLNHQAISATHCCECGDPIDE
                     RRRLAVQGCRTCASCQEDLELISKQRGSK"
     gene            complement(1625..2227)
                     /locus_tag="ACHY1N_005227"
     CDS             complement(1625..2227)
                     /locus_tag="ACHY1N_005227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047338.1"
                     /translation="MSYFLRKKWMVNLSGAGKILWTLNMKKDSYPYLICMTVSGLIFI
                     FLFFWWRADIYRVTFLNQSISHYYILFSMGIAFLLSLFWVKKGIVKQSGWKSLSAYLK
                     VYAGMCIFAGFFLIIPLTTLTYFLPGETSSYVAPYRYTSGSSKSCSGAEVDDPDLHEN
                     IRICYPYGNYEYDNIIYVEKKINTLGAVVTYAQTARDDTE"
     gene            2470..2637
                     /locus_tag="ACHY1N_005228"
     CDS             2470..2637
                     /locus_tag="ACHY1N_005228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047339.1"
                     /translation="MHFRVTGEWNGEPFNRVIEAENINDCYDHWMIWAQIAHADITNI
                     RIEELKEHQAA"
BASE COUNT          839 a          582 c          618 g          666 t
ORIGIN      
        1 gctaaagcgc tggcctgggg aaaacagtac gagaacgacg ccagagccct gtttgagttc
       61 acttccggcg tgaatgttac tgaatcaccg atcatctatc gcgacgaaag tatgcgtacc
      121 gcctgctctc cagatggttt atgcagtgac ggcaacggcc ttgaactgaa atgcccgttt
      181 acctcccggg atttcatgaa gttccggctc ggtggtttcg aggccataaa gtcagcttac
      241 atggcccagg tgcagtacag catgtgggtg acgcgaaaag atgcctggta ctttgccaac
      301 tatgacccgc gtatgaagcg tgaaggactg cattatgtcg tggttgagcg ggatgaaaag
      361 tacatggcgg gttttgacga gatggtgccg gagttcatcg aaaaaatgga cgaggcactg
      421 gctgaaattg gttttgtatt tggggagcaa tggcgatgaa gcatcctcac gataatatcc
      481 gggtaggtgc gatcactttc gtctactccg ttacaaagcg aggctgggta tttcccgacc
      541 tttctgttat ccaaaatcca ctgaaagccc agcggctggc tgaggagata aataataaac
      601 gaggggctgt atgcacaaag catctcctgt tgagttaaga acgagcattg agatggcaca
      661 tagccttgct caaattggag tcaggtttgt gccaatacca gtagaaacag acgaagaatt
      721 tcatacgtta gccacatccc tttcacaaaa gctggaaatg atggtggcga aagcagaagc
      781 agatgagaga gaccaggtat gacaaccact gaatgcattt ttctggcagc gggcttcata
      841 ttctgtgtgc ttatgcttgc cgacatgggg cttgttcagt gacacctcag caagaaaacg
      901 cccttcgcag cattgcccgt caggctaatt ctgaaatcaa aaaagccaga cagcagtttc
      961 cggataaaaa cgtcgatgac atttgccgta gcgtactgaa gaagcaccgc gaaacggtaa
     1021 cgctgatggg attcacaccg actcatttaa gcctggcgat cggcatgtta aacggcgtct
     1081 ttaaggaacg gtgagcatga aaagcaaaat catcagggag ctacaggctc cttttttatt
     1141 gttcgcattc accctcaagc gtattaacca acaattcagg gattaatgga agatggcaga
     1201 catcattgat tcagcatcag aaattgaaga attacagcgc aacacagcaa taaaaatgcg
     1261 ccgcctgaac caccaggcta tatctgccac tcattgttgt gagtgtggcg atcccataga
     1321 tgagcgaaga cgcctggccg ttcagggttg tcggacttgt gcaagttgcc aggaggatct
     1381 ggaacttatc agtaaacaga gaggttcgaa gtgagcgaaa ttaactagaa gccaaagata
     1441 aaatcatcgc tgagcaggag aaaatcgcta acggagaaaa gacagtaagt cagtatatga
     1501 aaaccgcatg atatcatcag ataaaaatcg atcgtaaagc gaaatattaa taccagaata
     1561 aacgagtcga ggtaaattat attacctcga taaattaact aaaacttgcc cgctatatac
     1621 tatctcattc agtatcatca cgcgcggtct gtgcatatgt tactaccgca cctaatgtat
     1681 taattttctt ttcaacatag ataatattat cgtactcata attgccatac ggatagcaaa
     1741 tgcgaatatt ctcatgtaga tcggggtcat ccacctcagc tccagaacaa ctttttgaac
     1801 taccggaagt ataccgatac ggtgcaacat aagacgatgt ctctccaggc aaaaaataag
     1861 ttagtgttgt aaggggtata atcagaaaaa atccagcaaa tatgcacatc cctgcataaa
     1921 ccttaaggta tgctgacaga ctcttccagc cgctttgttt tactatcccc ttcttaaccc
     1981 aaaacagaga taacagaaaa gctattccca tgctaaacag aatgtaatag tgggatatac
     2041 tctgattaag aaacgtgacc ctgtaaatat ctgcccgcca ccagaagaaa aggaaaataa
     2101 agatcaggcc tgaaactgtc atgcaaatca aataaggata cgaatctttt ttcatgttta
     2161 gcgtccataa aatttttcct gccccggaca aatttaccat ccattttttg cgcagaaaat
     2221 agctcattac ttactgcaca ataatacaca aaattgcgta aattttttgc atggatttta
     2281 gctctttcag ccgacgttta aggggtaaat agcatttcct aaaagcaact gcaccaaccc
     2341 aacagaatga gctaccgctt acgttgagag caaaaaagtg tatagcagca atgaacagca
     2401 tcctcgcact gacgaggatt tcttttatct gaactcgcta cggcgggttt tgttttatgg
     2461 agatgataaa tgcacttccg agtcacaggt gaatggaatg gagaaccatt caacagagtt
     2521 atcgaagcag agaacatcaa tgactgctat gaccactgga tgatatgggc gcagatagca
     2581 catgcagaca taaccaatat tcgaattgaa gaactgaaag aacaccaagc cgcctgatgg
     2641 cggctttttc ttgcgtgtaa ttgcggagac tttgcgatgt acttgacact tcaggagtgg
     2701 aacgc
//
LOCUS       DAZUDJ010000213         2677 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.218, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000213 DAZUDJ010000000
VERSION     DAZUDJ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2677
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.218"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(73..1263)
                     /gene="aspC"
                     /locus_tag="ACHY1N_005229"
     CDS             complement(73..1263)
                     /gene="aspC"
                     /locus_tag="ACHY1N_005229"
                     /EC_number="2.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate transaminase"
                     /protein_id="HFS4047340.1"
                     /translation="MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFD
                     ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMK
                     AAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(1448..2536)
                     /gene="ompF"
                     /locus_tag="ACHY1N_005230"
     CDS             complement(1448..2536)
                     /gene="ompF"
                     /locus_tag="ACHY1N_005230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HFS4047341.1"
                     /translation="MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHY
                     FSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNK
                     TRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVAT
                     YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADR
                     TNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKT
                     QDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVD
                     YIINQIDSDNKLGVGSDDTVAVGIVYQF"
BASE COUNT          665 a          662 c          642 g          708 t
ORIGIN      
        1 agcgcatcag gcaatgttgc gtttgtcatc agtctcagcc cgcttttcag cgggcttcat
       61 tgtttttaat gcttacagca ctgccacaat cgcttcgcac agcggagcca tgttatctgg
      121 tgtcatcccg gccacattta cgcgaccaga agcaaccgca tatacgccaa actcttcgcg
      181 cagacgcagc acttgttctt ttgtcaggcc actgaaggag aacatgccgt tctgtttgat
      241 gataaagctg aagtcgcggt ttgcgccttt ttcctgcagc gtattgacga acaactgacg
      301 catacgctga atacgctggc gcatatcagt cagctcttgt tcccaaatcg cacgtaacgc
      361 atcgttgctc aggatggtgg caacaacaga agcgccgtgt gctggtgggt tagagtagtt
      421 agcgcgaatc gccgctttca tttggctgaa tgcgcgatca acggtttcac tgtcggcagc
      481 aaccagagta caagcgccaa cacgctcgtt gtacaggcca aagtttttag agtaggaact
      541 ggcaacaatc agctctttat gcatagccgc gaaagcgcgc agtccttcag catcttcttc
      601 cagaccacgg gcaaaaccct ggtaagcgaa gtcaaacagc ggtaaccagc ctttctcaac
      661 ggagagttgt gccagtgtct gccattgttc cagcgtaggg tcgataccgg ttgggttatg
      721 gcagcagcca tggaacagca ctacgtcgcc agcctgagct tcattcaggc tgttaatcag
      781 tgcatcgaag tcaagagtgt gattttccgc atcataataa gcgtattcac gaacttccag
      841 acctgcagag ttaaagacgc tcttatggtt cggccagctt gggttgctca cccacactcg
      901 cttaacgctg gtattttttg ccaggaaatc ggcagctacg cgtagtgcgc cagtgccccc
      961 cggagtctgt gccgtgcgag cacgtttgtc attgatcagg gcgctacctt taccaaacag
     1021 cagttcctga gtgcagcgac caaattcagg gatgccgtca atgccgaggt aatttttggt
     1081 ggtttcattt tcgagcagat actgttcagc ctttttcacg ctggtcagta ccggggtttt
     1141 gcccgtctca tctttataga caccaatccc gaggttaatt ttgccgggac gttcatcggc
     1201 acgaaacaga tcggccaggc ccagaatcgg gtcggcagga gcggcggtaa tgttctcaaa
     1261 catgacgagg ttccattatg gttacagaag ggaagtccgc tatcagggta acgggagatt
     1321 tacaaaattc caactattac tgatgaaaac gcaggctgtt tttgcaagac gtgagattgc
     1381 tctggaaggt ataaaaaaaa caggaccaaa gtcctgtttt ttcggcattt aacaaagagg
     1441 tgtgctatta gaactggtaa acgataccca cagcaacggt gtcgtctgaa cctacgccca
     1501 gtttgttgtc agaatcgatc tggttgatga tgtagtcaac ataggtggac atgtttttgt
     1561 tgaagtagta ggttgcgccc acttcaaagt agttcaccag atcaacatca ccgatacctt
     1621 ctacgtcttt cgctttagat ttggtgtaag cgatggacgg acgcagaccg aaatcgaact
     1681 ggtattgcgc aactaacaga acgtcttgcg ttttgttggc gaagccgctg gtgtttgtaa
     1741 atttattagt gatcggcgta gcgttacggg tttcaccgta gttcgctgcc aggtagatgt
     1801 tgttcgcgtc gtacttcaga ccagtagccc actgttcagc ttttttaccg ttgccaagag
     1861 gttgagcttc ttgcaggttg gtacggtcag ctgcaccata agcaccaacg ataccaaagc
     1921 cttcgtattc gtagctgata gaaccgccaa caccgtcgcc gttagaacgg cgtgcagtgt
     1981 cacgctcgtt tttacccagg tactgaacag cgaagttcag gccatcaacc agaccaaaga
     2041 agttggagtt acgataggta gcaacgccgc caacacgacc aacgaagaag tcatcgctgt
     2101 atgcagtatc accaccaaat tctggcagca tatcggtgta acccagtgca tcataaacca
     2161 caccgtagtt acggccgtaa tcgaaagaac caacgtcagc gtatttaaga cccgcgaatg
     2221 ccagacgcgt tttgttacca gtttgagcgt cagcgccttc agagttgtta ccctggaagt
     2281 tatattccca ctgaccataa ccggtcagat cggaattgat ttgagtttcc cctttaaaac
     2341 caagacgggc ataggtcatg tcgccattgc caccgtaact gttttcaccg ttacccttgg
     2401 aaaaataatg cagaccaaca gctttaccgt acagatctac tttgttgcca tctttgttat
     2461 agatttctgc agcgtttgca gtacctgcta ctaacagagc agggacgatc actgccagaa
     2521 tattgcgctt catcattatt tattaccctc atggtttttt ttatgacacc tgccactgcc
     2581 gtcaataagt tctgtcaata aaaatttacg gaactattga tgagagtttg gtgtctttat
     2641 gtgtctgcag gcatctttcc attcaaacta acgtttc
//
LOCUS       DAZUDJ010000214         2635 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.219, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000214 DAZUDJ010000000
VERSION     DAZUDJ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2635
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.219"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            33..710
                     /gene="tnpA"
                     /locus_tag="ACHY1N_005231"
     CDS             33..710
                     /gene="tnpA"
                     /locus_tag="ACHY1N_005231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element accessory protein TnpA"
                     /protein_id="HFS4047342.1"
                     /translation="MSIIFNGHYRMKHRTWITEALRLHFEEHLPRVVAGRRLGVPKST
                     VCSMFVRFRRAGLSWPLPAGMSEQELDACLYGQFSTVPVVRPESTVISEAPVVKKRPR
                     RPNFPYEFKIALVEQSLQPGACVAQIARENGINDNLLFNWRHQYRKGGLLPSGKNMPA
                     LLPVTLTPEPDNKIPAPAQEPEQINTPSDSLCCELVLPAGTLRLKGKLTPALLQTLIR
                     EIKGSSH"
     gene            710..1057
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005232"
     CDS             710..1057
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858152.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFS4047343.1"
                     /translation="MISLPAGSRIWLVAGITDMRNGFNGLASKVQNVLKDDPFSGHLF
                     IFRGRRGDQIKVLWADSDGLCLFTKRLERGRFVWPVTRDGKVHLTPAQLSMLLEGINW
                     KHPKRTERAGIRI"
     gene            1077..>2635
                     /locus_tag="ACHY1N_005233"
     CDS             1077..>2635
                     /locus_tag="ACHY1N_005233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISCro1 family transposase"
                     /protein_id="HFS4047344.1"
                     /translation="MDTSLAHENARLRALLQTQQDTIRQMAEYNRLLSQRVAAYASEI
                     NRLKALVAKLQRMQFGKSSEKLRAKTERQIQEAQERISALQEEMAETLGEQYDPVLPS
                     ALRQSSARKPLPASLPRETRVIRPEEECCPACGGELSSLGCDVSEQLELISSAFKVIE
                     TQRPKQACCRCDHIVQAPVPSKPIARSYAGAGLLAHVVTGKYADHLPLYRQSEIYRRQ
                     GVELSRATLGRWTGAVAELLEPLYDVLRQYVLMPGKVHADDIPVPVQEPGSGKTRTAR
                     LWVYVRDDRNAGSQMPPAVWFAYSPDRKGIHPQNHLAGYSGVLQADAYGGYRALYESG
                     RITEAACMAHARRKIHDVHARAPTYITTEALQRIGELYAIEAEVRGCSAEQRLAARKA
                     RAAPLMQSLYDWIQQQMKTLSRHSDTAKAFAYLLKQWDALNVYCSNGWVEIDNNIAEN
                     ALRGVAVGRKNWMFAGSDSGGEHAAVLYSLIGTCRLNNVEPEKWLRYVIEHIQDWPAN
                     RVRDLLPWKVDL"
BASE COUNT          630 a          724 c          736 g          545 t
ORIGIN      
        1 tctggtctgt ttcctccggc tctacaaaaa taatgtccat catttttaat ggacactatc
       61 gtatgaaaca ccggacctgg atcactgaag ctttacgtct tcactttgaa gaacatttac
      121 cccgggttgt ggccgggcgt cgcctgggtg taccaaaatc aacagtttgt agtatgttcg
      181 tgcgctttcg gagagctggc ctttcgtggc ctttgcccgc aggcatgtcg gagcaggaac
      241 ttgatgcctg cctttacgga caattttcca cggtaccagt cgtacgtcct gaaagcaccg
      301 ttatatccga agcccccgtg gtaaaaaaac gtccccggcg gcccaacttc ccttatgagt
      361 ttaaaatcgc cttagtggag cagtcactgc agcccggagc ctgtgtggcg cagatcgccc
      421 gggaaaacgg aatcaacgat aacctgctct tcaactggcg ccatcaatac cggaaaggtg
      481 gcctgctgcc ttccggaaaa aatatgccgg cactgcttcc cgtgacgtta acgccggagc
      541 cggataataa aatcccggcc cccgcacagg aaccagagca gataaataca ccgtccgaca
      601 gtctgtgttg tgagctggtt ctgccggccg gaactctcag gcttaaaggt aaactgacgc
      661 cggcgttatt acagacactt atccgcgaaa taaaagggag cagccactga tgatatctct
      721 ccctgcaggt tcgcgtatct ggctggttgc aggtatcacc gatatgcgaa atggctttaa
      781 cggcctggca tcaaaagttc agaacgtcct gaaggatgac ccgttctccg gacacctgtt
      841 catcttccgc ggacgccggg gtgaccagat aaaagtgttg tgggctgaca gtgacggact
      901 gtgcctcttc accaaacgcc tggagcgggg ccgcttcgtc tggccagtca cccgtgacgg
      961 caaggtgcac cttactccgg ctcagttatc catgcttctt gaaggtatca actggaagca
     1021 cccgaaacga acggaacgcg ctggaatccg catataaccc gttgtaaagt gaggatatgg
     1081 acacctcact tgctcatgag aacgcccgcc tgcgggcact gttgcagacg caacaggaca
     1141 ccatccgcca gatggctgaa tacaaccgcc tgctctcaca gcgggtggcg gcttatgctt
     1201 ccgaaatcaa ccggctgaag gcgctggttg cgaaactgca acgtatgcag ttcggtaaaa
     1261 gctcagaaaa acttcgtgca aaaaccgaac ggcagataca ggaagcacag gagcgaatca
     1321 gcgcacttca ggaagaaatg gcggaaacgc tgggtgagca atatgacccg gtactgccat
     1381 ccgccctgcg ccagtcttca gcccgtaaac cgttaccggc ctcacttccc cgtgaaaccc
     1441 gggttatccg gccggaagag gaatgctgtc ctgcctgtgg tggtgaactc agttctctgg
     1501 gatgtgatgt gtcagagcaa ctggagctta tcagcagcgc ctttaaggtt atcgaaacac
     1561 aacgtccgaa acaggcctgt tgccggtgcg accatatcgt gcaggcacca gtaccttcaa
     1621 aacccattgc acgcagttat gccggagcgg ggcttctggc ccatgttgtc accgggaaat
     1681 atgcagacca tctgccgtta taccgccagt cagaaatata ccgtcgtcag ggagtggagc
     1741 tgagccgtgc cacactgggg cgctggacag gtgctgttgc tgaactgctg gagccgctgt
     1801 atgacgtcct gcgccagtat gtgctgatgc ccggtaaagt ccatgctgat gatatccccg
     1861 tcccggtcca ggagccgggc agcggtaaaa cccggacagc ccggctgtgg gtctacgtcc
     1921 gtgatgaccg taacgccggt tcacagatgc ccccggcggt ctggttcgcg tacagtccgg
     1981 accggaaagg tatccatcca caaaatcacc tggccggtta cagcggtgtg cttcaggccg
     2041 atgcttacgg tggttaccgg gcgttatacg aatccggcag aataacggaa gccgcgtgta
     2101 tggctcatgc ccggagaaaa atccacgatg tgcatgcaag agcgcccacc tacatcacca
     2161 cggaagccct gcagcgtatc ggtgaactgt atgccatcga ggcagaggtc cggggctgtt
     2221 cagcagaaca gcgtctggcg gcaagaaaag ccagagccgc gccactgatg cagtcactgt
     2281 atgactggat acagcaacag atgaaaacac tgtcgcgtca ctcagatacg gcaaaagcgt
     2341 tcgcatacct gctgaaacag tgggatgcac tgaacgtgta ctgcagtaat ggctgggtgg
     2401 aaatcgacaa caacatcgca gagaacgcct tacggggagt ggccgtaggc cggaaaaact
     2461 ggatgttcgc gggttccgac agcggtggtg aacatgcggc ggtgttgtac tcgctgatcg
     2521 gcacatgccg tctgaacaat gtggagccag aaaagtggct gcgttacgtc attgaacata
     2581 tccaggactg gccggcaaac cgggtacgcg atctgttgcc ctggaaagtt gatct
//
LOCUS       DAZUDJ010000215         2593 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.220, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000215 DAZUDJ010000000
VERSION     DAZUDJ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2593
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.220"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..666
                     /gene="tnpA"
                     /locus_tag="ACHY1N_005234"
     CDS             <1..666
                     /gene="tnpA"
                     /locus_tag="ACHY1N_005234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element accessory protein TnpA"
                     /protein_id="HFS4047345.1"
                     /translation="QTKKDIPCFRSYLPDALRLRFEDKLTIRAIAQRLGLSHSTIHTL
                     FQRFIASGIAWPLPDSVSLAQLDAILYANRKKELTEPQISEGTWRKERRASYSREFKV
                     RLAKQALQPGAVVARIAREHGINDNLLFKWKSQYEDGLLSDDDIQECMPVPVALTDTP
                     EPTRPVTNPFWRNKPDECPESDPGNVPRCELHLKSGVVKLFDPLTPEMLRALIREMKG
                     GTR"
     gene            663..1010
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005235"
     CDS             663..1010
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858152.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFS4047346.1"
                     /translation="MITLPTGTRIWIIAGITDMRCGFNGLASKVQNTLKDDPFSGHIF
                     VFRGRSGKMVKILWADRDGLCLFAKRLERGRFVWPVTREGKVHLTPAQLSMLLEGIAW
                     QHPKRTERPGIRI"
     gene            1030..2582
                     /locus_tag="ACHY1N_005236"
                     /pseudo
     CDS             1030..2582
                     /locus_tag="ACHY1N_005236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
BASE COUNT          656 a          701 c          718 g          518 t
ORIGIN      
        1 cagacaaaaa aagatattcc ctgcttccgt tcttatttgc ctgatgctct gcgtttaaga
       61 tttgaagata aactgaccat ccgggccatc gctcagcgtc taggtctcag tcattccaca
      121 atacatacgc tttttcagcg atttattgca tccggtatcg catggccatt gcccgattca
      181 gtttcattag ctcagcttga tgccatcctt tatgccaaca gaaagaagga attaacagag
      241 cctcaaatca gcgaaggcac atggcgaaaa gaacggcgag ccagctacag ccgtgaattt
      301 aaggtccgtc tggctaagca ggcattacag cccggtgctg ttgttgcccg gatcgccaga
      361 gagcacggta tcaatgataa cctgctgttt aaatggaaaa gccagtacga ggacggctta
      421 ctgagcgatg atgacataca ggaatgcatg cctgtcccgg tggctctgac tgatacgcca
      481 gagccgacca gaccagttac aaatcccttc tggcgtaaca agcctgatga gtgccctgag
      541 agtgatcccg gaaacgtccc acggtgcgag ctgcatctta aatcaggtgt ggtaaaactg
      601 tttgaccctc tcactccgga aatgttacgg gcgctaatcc gcgaaatgaa aggaggtacc
      661 cgatgataac gctgccaacc ggtaccagaa tctggatcat cgctggcatc acagatatgc
      721 gttgtggctt caacggcctg gcttcgaagg tgcagaacac gctgaaagat gacccgttct
      781 ccgggcatat cttcgtcttc cggggccgca gtggcaaaat ggtgaaaata ctgtgggccg
      841 atcgtgacgg gttatgcctg ttcgccaaac gcctggaacg gggccgcttc gtctggccgg
      901 taacccggga agggaaagtg cacctgacgc cagctcagtt atccatgcta ctggagggga
      961 tcgcgtggca acatcccaaa cggacagaac ggcctggcat ccggatataa cccgtgataa
     1021 aacaggggaa tgaacaacac actccccgac gacatcgagc aactgaaggc cctgctgatc
     1081 gcacagcagg ctgttatcgt ctgtctggtg aaataaccgg ctatgcccgc gagatcagct
     1141 cactcagagc gctggtcgct aaactgcaga gaatgttgtt cggtcgcagc agcgagaaaa
     1201 gccgcgagaa gatagaaaag aagatcgcac gggcagaaac gcgtataacc gagctccaga
     1261 acaggcttgg tgaggcgcag ttgcaactca cctcaatggc cggagagaca gcgccgaaaa
     1321 catcagactc tcccgtccgc aaagcacttc cggcaacact tccccgtgac aggcaggtta
     1381 tctccccggc agaaaccgaa tgccccgtct gcagcggcaa actgaaaccg ctgggagaaa
     1441 gcatctctga acaactggat atcatcaaca ccgcgttcag ggtaatcgaa acggttcgcc
     1501 caaaactggc ctgcagccgg tgcgactgta tagttcaggc tccgcagcca ccaaaaccca
     1561 tcgagcgcag ttacgccagt ccggctctgc tggcccgcat aatcatggct aagttcgccg
     1621 agcatctgcc gctgtaccgt cagtcggaaa tctatgcccg ccagggcgtg gagctgcacc
     1681 gcaatacgat ggggcgctgg gttgacatca tgggagagca gcttcgcccg ctgtatgatg
     1741 aactgaagca ctatgtgctg atggcgggta aagtgcatgc cgatgacacg ccggtaaatg
     1801 tactggagcc gggtcagggt aaaacccgta ccggacggct gtgggtctat gttcgtgacg
     1861 atcgcaacgc cggttcgacc atgccggcag cggtgtggtt ctcatactct cccgaccgca
     1921 aaggcatcca cccacagcaa catctggcgg actacagagg tatcctgcag gccgatgcat
     1981 atgcgggtta caatgctctt tacgaaagcg gtcaggtaac cgaagcggct tgtatggcac
     2041 atgcccgacg caagatccac gatgtacatg tccgccatcc aacgacagta acgggagaag
     2101 cgctccgtcg tatcggggaa ctgtacgcta tcgaggctga gatccgcggc agtccggcag
     2161 aagagcgact ggcggtcaga aaagccagaa cggtaccgct aatgcagtcg ttgtatgagt
     2221 ggctccaggg gcagatgagc acgctgtcgc gccactcgga tacagcgaaa gcgttcacct
     2281 atctgctgaa gcaatgggac gctctgaacg aatactgccg caatggctgg gtggagatcg
     2341 acaataacct gtgtgaaaac gccctccggg tagttgcact ggggcggcgt aactacatgt
     2401 tcttcggctc tgatggtgga ggcgagagtg cggcagtgat gtacagcctg atcggtagct
     2461 gcaaacttaa cggaatcgag ccggaaacgt ggctatgcca cgtgatcagt gtaatcaaca
     2521 cctggcctgc caaccgcgtg aaagagttgt tgccctggaa tgtcactcaa tctgtaaact
     2581 aatttttacc cca
//
LOCUS       DAZUDJ010000216         2558 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.221, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000216 DAZUDJ010000000
VERSION     DAZUDJ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2558
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.221"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            192..1733
                     /gene="istA"
                     /locus_tag="ACHY1N_005237"
     CDS             192..1733
                     /gene="istA"
                     /locus_tag="ACHY1N_005237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family transposase"
                     /protein_id="HFS4047347.1"
                     /translation="MPTVPISMRKLKEILRLKYGVGLSHRQIGRSLAISPSVVSRYAN
                     RAAQLGIKQWPLPTGWDDTKLKHAFLQTQVKMKKHSLPDWATVHRELRNKCVTLQLLW
                     EEYCERNPGGFYSYNHYCRMYREWLKTTSPSMRQVHKAGEKLFVDYCGPTVGVTDPET
                     GEIRTAQVIVAVLGASSYTWAEATWSQQLEDWVMSHVRCFQWLGGVPELVVPDNLKSA
                     TSRACKYDPDVNPTYQQMLEHYNVAVLPARPRKPKDKAKAEVGVQVVERWIMARIRHE
                     IFYSLASLNQRIRELLERLNNKIMQKLGYSRAELFIQLDKPALKPLPEASYSYTLVKK
                     VRVHADYHVEIDKHYYSVPCSLLGQQLEAWISGELVRLFNQGQEVAVHPRKRTYGYST
                     RNEHMPEAHRQHATWTPERLLEWAGHIGSETHSYVLHILNSRPHPEQSYRFCLGLLNL
                     HKKYSKARLNAACARALKTKVWRLSGIKSILEKGLDKQPVQDPKPDLLSTMEHENVRG
                     SEYYH"
     gene            1748..2494
                     /gene="istB"
                     /locus_tag="ACHY1N_005238"
     CDS             1748..2494
                     /gene="istB"
                     /locus_tag="ACHY1N_005238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family helper ATPase
                     IstB"
                     /protein_id="HFS4047348.1"
                     /translation="MNHLYEQLTALKLTGFRDALKKQLAQPGTYQELGFEERLSLLTA
                     EELTCRENRKAERLIKHARFRLNAELSKLDYRNNRGLDRALIRSLSQGNWLTLKQNIL
                     LTGATGSGKTFLACALGHNACRQGYKVYYYRLKALMEQCYQGHADGRYSKLLTRLNNS
                     DLLLLDDWGLEPLSSEQRSDLLEIVDLMYQRGSIIVVSQLPVENWYKMIGDSTHADAI
                     LDRLVHGSIKIELKGESMRKIQSPLTEGDQ"
BASE COUNT          732 a          600 c          612 g          614 t
ORIGIN      
        1 cgtattttca tgaaaggaga tcactcaata acttccatcg agatcgggta ataacatttg
       61 aacagatcgc tgaataacat cgatggagat cacttttgac tcattttgtt attcagtgat
      121 ctccatcaat gttattggaa cttcacaggt gtgttgatct gtatcttttg ccattccggt
      181 aaaggatacc tatgccaaca gttccaattt ctatgagaaa acttaaagaa attcttaggc
      241 ttaaatacgg tgttggactc agccatcgac aaattggtcg tagtcttgca atctcccctt
      301 ccgttgtatc cagatatgct aatcgggcgg ctcaacttgg cataaagcag tggcccttac
      361 ctacaggatg ggatgataca aaactaaaac atgcgttcct tcagacccag gttaagatga
      421 agaagcactc tctgcctgac tgggctacag tacaccggga actgcgtaat aaatgcgtga
      481 cgctgcagct actctgggaa gaatactgtg agcgtaatcc aggcggtttt tacagctata
      541 accattactg ccggatgtac cgtgaatggc tcaaaaccac ttcaccatca atgcgtcagg
      601 tacataaagc tggcgaaaaa cttttcgttg attactgtgg acctaccgtt ggcgttaccg
      661 accctgagac cggagaaata agaactgctc aggtcatcgt agctgttctc ggggcatcaa
      721 gttacacatg ggcagaggcc acctggtctc agcagcttga agactgggtg atgagtcatg
      781 ttcgctgctt ccagtggttg ggtggcgttc ctgaacttgt tgttccggac aatctgaaaa
      841 gcgccacatc cagggcatgt aagtatgatc ctgacgttaa ccctacctac cagcagatgc
      901 ttgagcatta taatgtcgca gttttgcctg cgcggccacg taaaccgaaa gataaagcca
      961 aagctgaagt tggcgttcag gttgttgaac gctggatcat ggcccgaatc aggcatgaga
     1021 tcttctacag ccttgcatcg cttaatcagc gcattcggga gttgctggaa agactgaata
     1081 acaaaataat gcagaagttg ggttattcac gtgcagaact cttcatccag cttgataaac
     1141 ccgcactgaa gcctcttcct gaagccagtt acagttacac cctggtgaag aaagtcagag
     1201 ttcatgccga ttaccacgtg gaaatcgaca aacattacta ctcggttcca tgttcgctgt
     1261 taggccagca actggaagca tggatctccg gagaactggt aagactcttc aatcaggggc
     1321 aggaggttgc tgtgcacccg cgcaagcgta cttatggcta cagtacccgc aacgagcaca
     1381 tgcctgaagc tcatcgacag catgccacct ggacgccaga gcgtcttctg gaatgggcgg
     1441 ggcacatagg cagtgaaact catagttatg tgcttcatat actgaactct cgtccacatc
     1501 cggaacaaag ctatcgcttc tgccttggac tcctgaacct tcataaaaaa tacagtaaag
     1561 ccagacttaa tgcagcatgt gcaagagctc tgaaaacaaa ggtatggcgt ctgtcaggta
     1621 ttaaatcgat cctggaaaaa ggtctggata aacaacctgt tcaggatcca aaaccagatc
     1681 tgttatccac gatggaacac gaaaacgtac gcggcagtga gtattaccac tgatacggga
     1741 tccaatgatg aatcatcttt acgaacaact gaccgcactt aaactcaccg gcttccgtga
     1801 tgcgcttaaa aagcaacttg ctcagccggg cacataccag gagctgggct tcgaagaacg
     1861 cctgtcatta ctgacagcag aagaactaac ctgccgtgaa aacaggaagg cagagcgtct
     1921 gatcaaacat gcacggttca gacttaatgc tgagttatca aagctggatt atcgtaacaa
     1981 tagagggctg gacagggccc tcatccgttc actcagtcag ggaaactggt taaccctgaa
     2041 acaaaatatt ttactgaccg gggccaccgg cagcggtaaa acgttcctgg catgtgcact
     2101 tggtcataat gcctgccgac agggatacaa ggtctactat tatcgcctta aagcgctgat
     2161 ggaacagtgc tatcaggggc atgctgatgg aagatacagc aaacttttga ccaggctgaa
     2221 taatagcgat ctgctgcttc tggatgactg ggggctggaa cctctctcat cagaacagcg
     2281 tagcgacctg ctggaaatag tggatctgat gtaccaacga ggctcaatca tcgtagtgag
     2341 ccagttgccg gtggaaaact ggtacaaaat gatcggagac tccacacatg cggatgccat
     2401 cctagatcga ctggttcatg gcagtatcaa gatcgaactt aaaggagaat caatgcggaa
     2461 aatacaatct ccgttgaccg aaggagatca gtgaaggtaa tttaaaaacg gttctgtgaa
     2521 agtgacacga accgatctcc atcgatgtta ctcaccga
//
LOCUS       DAZUDJ010000217         2502 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.222, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000217 DAZUDJ010000000
VERSION     DAZUDJ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2502
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.222"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..247
                     /locus_tag="ACHY1N_005239"
     CDS             <1..247
                     /locus_tag="ACHY1N_005239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415090.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1398 family protein"
                     /protein_id="HFS4047349.1"
                     /translation="IKGLKKVVNVKFSRNTHLIETSFDRLKSREITFQQYRENLAKAG
                     VFRWVTNIHEHKRYYYTFDNSLLFTESIQNTTQIFPR"
     gene            538..831
                     /gene="bor"
                     /locus_tag="ACHY1N_005240"
     CDS             538..831
                     /gene="bor"
                     /locus_tag="ACHY1N_005240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serum resistance lipoprotein Bor"
                     /protein_id="HFS4047350.1"
                     /translation="MKKMLLATALALLITGCAQQTFTVQNKQTAVAPKETITHHFFVS
                     GIGQKKTVDAAKICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSK"
     gene            complement(922..1104)
                     /gene="rzoD"
                     /locus_tag="ACHY1N_005241"
     CDS             complement(922..1104)
                     /gene="rzoD"
                     /locus_tag="ACHY1N_005241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage lysis lipoprotein RzoD"
                     /protein_id="HFS4047351.1"
                     /translation="MRKLKMMLCVMMLPLVVVGCTSKQSVSQCVKPPRPPAWIMQPPP
                     DWQTPLNGIISPSERG"
     gene            complement(1321..1818)
                     /gene="rrrD"
                     /locus_tag="ACHY1N_005242"
     CDS             complement(1321..1818)
                     /gene="rrrD"
                     /locus_tag="ACHY1N_005242"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme RrrD"
                     /protein_id="HFS4047352.1"
                     /translation="MPPSLRKAVAAAIGGGAIAIASVLITGPSGNDGLEGVSYIPYKD
                     IVGVWTVCHGHTGKDIMLGKTYTKAECKALLNKDLATVARQINPYIKVDIPETTRGAL
                     YSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVC
                     LWGQQ"
     gene            complement(1818..2033)
                     /gene="essD"
                     /locus_tag="ACHY1N_005243"
     CDS             complement(1818..2033)
                     /gene="essD"
                     /locus_tag="ACHY1N_005243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein EssD"
                     /protein_id="HFS4047353.1"
                     /translation="MKFMDKLTTGVAYGTSAGSAGYWFLQLLDKVTPSQWAAIGVLGS
                     LVFGLLTYLTNLYFKIKEDKRKAARGE"
BASE COUNT          740 a          569 c          506 g          687 t
ORIGIN      
        1 aataaaagga cttaaaaagg ttgtaaatgt taaattctca agaaatacgc atcttataga
       61 aacgtccttt gataggttga aatcaagaga aatcacattt cagcaataca gggaaaatct
      121 tgctaaagca ggagttttcc gatgggttac aaatatccac gaacataaaa gatattacta
      181 tacctttgat aattcattac tatttactga gagcattcag aacactacac aaatctttcc
      241 acgctaaatc ataacgtccg gtttcttccg tgtcagcacc ggggcgttgg cataatgcaa
      301 tacgtgtacg cgctaaaccc tgtgtgcatc gtttttaatt attcccggac actcccgcag
      361 agaagttccc cgtcagggct gtggacatag ttaatccggg aatacaatga cgattcatcg
      421 cacctgacat acattaataa atattaacaa tatgaaattt caactcattg tttagggttt
      481 gtttaatttt ctacacatac gattctgcga acttcaaaaa gcatcgggaa taacaccatg
      541 aaaaaaatgc tactcgctac tgcgctggcc ctgcttatta caggatgtgc tcaacagacg
      601 tttactgttc aaaacaaaca gacagcagta gcaccaaagg aaaccatcac ccatcatttc
      661 ttcgtttctg gaattgggca gaagaaaact gtcgatgcag ccaaaatttg tggcggcgca
      721 gaaaatgttg ttaaaacaga aacccagcaa acattcgtaa atggattgct cggttttatt
      781 actttaggca tttatactcc gctggaagcg cgtgtgtatt gctcaaaata attgcatgag
      841 ttgcccatcg atatggtcag ctctatctgc actgctcatt aatatacttc tgggttcctt
      901 ccagttgttt ttgcatagtg atcagcctct ctctgagggt gaaataatcc cgttcagcgg
      961 tgtctgccag tcggggggag gctgcattat ccacgccgga ggccgtggtg gcttcacgca
     1021 ctgactgaca gactgctttg atgtgcaacc gacgacgacc agcggcaaca tcatcacgca
     1081 gagcatcatt ttcagctttc gcatcagcta actccttcgt gtattttgca tcgagcgcag
     1141 caacatcacg ctgacgcatc tgcatgtcag taattgccgc gttcgctagc ttcacttctc
     1201 tggcattttt gtcgcgctgg gctttgtagg cgattgcgtt atcacggtaa tgattgaccg
     1261 cccatgacag gctgacgatg atgcagataa tcagagcgga tataatcgcg gttactctgc
     1321 tcactgttgc ccccacaaac agacttcacg ctcaatctca cgacgagtca tcaggccttt
     1381 ccattgctta ccgccagcgt atgtccagcg acgcagctga tcacatgcgc ctttgatatc
     1441 gccctggttt attttgcgaa gaagcgtcga tgttctaaaa ttgccagcac ccacattgta
     1501 aacgaatgag taaagagcgc cgcgcgttgt ttccggtata tcaactttga tatacgggtt
     1561 aatttgtctg gcgacagtgg caaggtcttt attcaagagt gctttgcatt ctgctttggt
     1621 atacgtttta ccgagcatga tgtcttttcc ggtgtgtccg tgacatacag tccatacacc
     1681 aacaatatct ttgtatggta tgtagctgac accttccaga ccatcgttac cacttgggcc
     1741 agtgattaac actgatgcta tagcaattgc tccgccacca atagcagcag caacggcttt
     1801 tcgtaatgat ggaggcatta ttcacctctc gcagccttgc gcttatcttc tttaatcttg
     1861 aaataaaggt ttgtcaggta cgtcagcagg ccaaatacca ggctacccag cacacctatt
     1921 gctgcccact gtgagggagt gactttatcg agcagctgta aaaaccagta accggcacta
     1981 cctgctgagg tgccataggc gactccagtt gttaacttat ccatgaattt cataacccca
     2041 cctcgcagac aaagcgggtg taaattgagg gaatacaacg tatcgcaaaa aagcagaaac
     2101 gtaactgact ccgagtcagt gaataactca ggtattgagt tatcagctaa tatcgagact
     2161 caaaaaatgg aaaaaccagc tcgacggcgg gtttaagctg tgtgacgaag taaccactct
     2221 taacagcata accaattttt tacgtacgta aaccactgaa tgatatttat gagaatgcta
     2281 ccgagtgttc aaaacatcac cacaaataca taagaaaacc tcaacaaata accaataaat
     2341 aatttccagt gttattttta gccggtttaa attaaacaga cgaattatag aaccaccata
     2401 aataacagcc attaatataa attagctaat agatttattt ttgttcaaat aagagccata
     2461 aataggtttc gatagaaaaa gttcagataa aaatagagat ct
//
LOCUS       DAZUDJ010000218         2477 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.223, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000218 DAZUDJ010000000
VERSION     DAZUDJ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2477
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.223"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            65..499
                     /locus_tag="ACHY1N_005244"
     CDS             65..499
                     /locus_tag="ACHY1N_005244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4047354.1"
                     /translation="MDKPTDWRSGTRRIFSNEFKLHMVELASKPNANVAQLAREHGVD
                     NNLIFKWLRLWQREGRISRRMPPTIVGPTVSQSFPASPTLVPVELIDTPRCATDAPAP
                     EALSVACAASCHVEFHYGKMMLENPSPELLTVLIRELTGRGR"
     gene            496..846
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005245"
     CDS             496..846
                     /gene="tnpB"
                     /locus_tag="ACHY1N_005245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309365.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFS4047355.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQIQHVLDDNPFSGHLF
                     IFRGRRGDTIKILWADADGLCLFTKRLEEGQFIWPAVRDGKISITRSQLAMLLDKLDW
                     RQPKTSRLNALTML"
     gene            877..>2477
                     /locus_tag="ACHY1N_005246"
     CDS             877..>2477
                     /locus_tag="ACHY1N_005246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc43 family transposase"
                     /protein_id="HFS4047356.1"
                     /translation="MSQKYLIRIAELERLLSEQAEALRQKDQQLSLVEETEAFLRSAL
                     ARAEEKIEEDEREIEHLRAQIEKLRRMLFGTRSEKLRREVEQAEALLKQREQESDRYS
                     GREDDPLVPRQLRQSRHRRPLPAHLPREIYRLEPEESCCPECGGELDYLGEVSAEQLE
                     LVSSALKVIRTERVKKACTKCDCIVEAPAPSRPIERGIAGPGLLARVLTGKYCEHLPL
                     YRQSEIFARQGVELSRALLSNWVDACCQLMTPLNDALYSYVMNTRKVHTDDTPVKVLA
                     PGRKKAKTGYIWTYVRDDRNAGSPEPPAVWFAYSPDHQGKHPEQHLRPFRGILQADAF
                     AGYDRLFSAEREGGALTEAGCWAHARRKIHDVYISTKSATAEEALKLIGELYAIEHEI
                     RGLPVSERLAVRQMQSKPLLTSLYKLMQEKEHTLSKKCRLRDAFRYIRKHWVALCNFC
                     DDGLAEADNNTAERALRAVCLGKKNYVFFGSDHGGERGALLYGLIGTCRLNGIDPEAY
                     LRHILSVLPEWPSNRVDELLPWNVVL"
BASE COUNT          613 a          637 c          683 g          544 t
ORIGIN      
        1 tctgtaacac ctgctccttg cagactaaat tagagctcct tctaaattag acggagttct
       61 attgatggat aaacctacag actggcgctc cggaacccgc cggatatttt ctaatgaatt
      121 taaacttcat atggttgaac tggcttcgaa accaaatgcc aatgttgcac aactggcccg
      181 ggaacatggc gttgataaca acctgatttt taaatggcta cgcctctggc aaagagaagg
      241 acgtatttct cgtagaatgc ctccaactat tgtaggccct acagtatcac aatcttttcc
      301 ggcctctccg actctggttc cagtggaact tatcgacacc ccgcgctgtg ctacagatgc
      361 tcctgctccg gaggcattat cagttgcttg tgcagcttcc tgccatgtgg aattccatta
      421 cggtaaaatg atgctggaaa atccttcacc agagctgctc acggtgttga tccgtgagct
      481 gaccgggagg ggacgatgat ttcactccca tcaggtaccc gtatctggct cgttgccggc
      541 gttactgata tgcgtaaatc cttcaacggt ctgggggagc agatacagca tgtgctggat
      601 gataacccct tctccggtca cctgtttatc ttccgtggcc gacggggaga cacgattaaa
      661 atcctgtggg ctgatgctga tggtctgtgc ctgttcacca aacgccttga ggaaggtcag
      721 tttatctggc ctgcggtgcg tgacggtaag atatccatta cccgctcgca actggcaatg
      781 ctcctcgata agctggactg gcgtcagcca aaaacatccc gccttaacgc actgacaatg
      841 ttgtaaaaaa ctcctgaccg cattataaaa acggccatga gtcagaaata cctcattcgc
      901 atcgctgagc tggaaaggct gctctctgag caggctgaag ccctccgtca gaaagaccag
      961 caactgagtc tggttgaaga gacggaggcc ttcctgcgct ctgcactggc acgtgccgaa
     1021 gaaaagatcg aagaagatga acgggaaata gagcatctgc gggctcagat agaaaaactg
     1081 cgccggatgc tgttcggaac ccgttctgaa aaactgcgtc gtgaggttga acaggctgaa
     1141 gccctgctga aacaacgcga gcaggaaagc gatcgttaca gtgggcgtga ggatgacccg
     1201 ctggttcccc gccagttgcg acagtcgcgc catcgtcgtc cgttaccggc acatctcccc
     1261 cgtgaaatat accgcctgga gcctgaagaa agctgttgcc cggagtgtgg cggtgagctg
     1321 gattatctgg gggaagtcag cgcagaacaa ctggaactgg tgagcagcgc cctgaaagtg
     1381 atccgcacag aacgggtaaa aaaagcctgt acaaaatgtg actgcatcgt tgaagcaccg
     1441 gcaccatccc gtccgataga gcgtggtatc gcgggcccgg ggttacttgc ccgcgtgtta
     1501 acgggaaaat actgcgaaca cctgccactg tatcgtcaga gtgaaatctt tgcccgccag
     1561 ggtgtcgaac tgagccgtgc cttactctcc aactgggttg atgcgtgctg ccagttaatg
     1621 acgccgctga atgatgccct gtacagttat gtgatgaaca cccgcaaggt tcacactgat
     1681 gacacaccag taaaagtact ggcaccgggc aggaagaagg cgaaaacagg atatatctgg
     1741 acgtatgtcc gggatgaccg aaatgccggt tcgccagaac ctccggcggt ctggttcgcc
     1801 tactcaccgg accatcaggg taaacatccg gagcaacacc ttcgtccctt ccggggtatc
     1861 ctgcaggcag atgcgttcgc aggttacgat cggctgttca gtgccgaacg tgaaggcggc
     1921 gcgttgacgg aagcaggatg ctgggctcat gcgcggcgca aaatccacga tgtatatatc
     1981 agtaccaaaa gcgcgacggc ggaagaagca ctgaaactaa tcggcgaact gtacgccatt
     2041 gagcacgaaa tacgcgggtt gccggtgtct gaacgcctgg cggtcaggca aatgcagagt
     2101 aaaccgctac tgacttccct gtataagctg atgcaggaga aagaacacac gttatcgaaa
     2161 aaatgccgtc tgagagatgc gttccggtat atcaggaagc actgggttgc gttgtgcaac
     2221 ttctgtgatg acggtctggc ggaggcggac aataacacag cggaaagagc gcttcgtgca
     2281 gtctgtctcg gaaagaaaaa ttacgtgttc ttcggtagcg atcacggcgg cgagcgtggt
     2341 gcactgttgt acgggctgat cggcacctgc cggttgaatg gtatcgatcc ggaagcgtat
     2401 ctgcgccata tcctgagcgt actgccggaa tggccttcca accgagttga cgaactcctg
     2461 ccatggaacg tagtact
//
LOCUS       DAZUDJ010000219         2468 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.224, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000219 DAZUDJ010000000
VERSION     DAZUDJ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2468
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.224"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1155
                     /locus_tag="ACHY1N_005247"
     CDS             join(<1..236,236..1155)
                     /locus_tag="ACHY1N_005247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612262.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4047357.1"
                     /translation="FTPEFRLECAQLIVDKGYSYRQASEAMNVGSTTLESWVRQLRRE
                     RQGITPSATPITPDQQRIRELEKQVRRLEEQNTIFKKGYRALNVRLAERFTIAARLSD
                     SHTVVSLCSALEIHRSSYRYWRKRRDTVNPARVRLCSEIRRAWNQSRGSAGARTLAEM
                     LTQNGVPMSRYRAGRLMKYLNLSSCQPGKHQYKNARQEHTSLPNLLERQFAVPEPDRV
                     WCGDITYLWAGNRWCYLAVVMDLFARRVIGWSLSAHADTALISSALRMAYETRGQPRD
                     VVFHSDQGSQYTGLKYQQLLWRCRINQSVSRRGNCWDNSPMERFFRSLKTEWVPTNGY
                     AGKDEARQQINDYILNYYNSVRPHHYNGGLTPEESENRYHFYCKTVANIT"
     gene            1165..1716
                     /locus_tag="ACHY1N_005248"
                     /pseudo
     CDS             1165..1716
                     /locus_tag="ACHY1N_005248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF932 domain-containing protein"
     gene            1716..1961
                     /locus_tag="ACHY1N_005249"
     CDS             1716..1961
                     /locus_tag="ACHY1N_005249"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047358.1"
                     /translation="MQHVSEGVIQVPELPDAPEALPGCRSISDDDLCAWCTRLLYRPG
                     ELSLCRLSTGNGIWPSVCDRNGYAYGCPEFQQNIIHP"
     gene            2055..>2468
                     /locus_tag="ACHY1N_005250"
     CDS             2055..>2468
                     /locus_tag="ACHY1N_005250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HFS4047359.1"
                     /translation="MKTLSQNTTSSACAPETGLQQLVATIVPDEQRISFWPQHFGLIP
                     QWVTLEPRIFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDENWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYR"
BASE COUNT          593 a          657 c          681 g          537 t
ORIGIN      
        1 cttcacccct gagttcaggc tggaatgtgc acagctgatt gttgataagg gctactcata
       61 tcgacaggcc agtgaagcga tgaatgtcgg ttcaaccacg cttgagagct gggtacgcca
      121 gctcaggcga gagcgccagg gtattacgcc ctctgccaca cccattactc cagaccagca
      181 acgtatccgc gagctggaaa agcaagttcg ccgtctggag gaacaaaata cgatattaaa
      241 aaaggctacc gcgctcttaa tgtccgactc gctgaacggt tcacgatagc cgccagacta
      301 agtgacagcc acacggttgt cagcctgtgt tctgctctgg aaatacaccg cagcagttac
      361 cggtactggc gaaaacgacg cgatacggtt aatccggcac gagtcaggtt gtgcagcgaa
      421 atacgccggg cgtggaacca aagtcggggc tctgcgggcg cgcgcactct ggctgaaatg
      481 ctgactcaaa acggcgtccc gatgagccgt taccgtgccg gacgtctgat gaaatatctg
      541 aacctgagca gttgtcagcc cggaaaacat cagtataaaa atgcccgtca ggagcatacc
      601 agcctgccga atctgcttga gcgtcagttc gcagtaccgg agccagaccg ggtatggtgt
      661 ggagatatta cgtatctctg ggcaggaaat cgctggtgct atctggcggt tgttatggat
      721 ctttttgccc gcagggttat cggctggagt ctgtcagcgc atgccgatac cgcactgata
      781 agcagtgccc tgcggatggc ctatgagacg cgtggccaac cccgggatgt cgtgttccat
      841 agcgaccagg gaagccagta tacaggcctt aaatatcaac aacttctctg gcgttgcaga
      901 ataaatcaaa gcgtcagtcg gcggggaaac tgctgggata acagccccat ggaacgcttc
      961 ttccgcagtc tgaaaacaga atgggtgcca acgaatggtt acgcaggcaa ggacgaggcc
     1021 cggcagcaaa ttaatgatta catattgaac tactacaaca gcgtcagacc tcaccattat
     1081 aacggtgggc tgacgccgga agagtcagag aacagatacc atttttactg taaaaccgtg
     1141 gccaatatta cttgaccact acacggagag ataaacggag aacatgtccc tgaaattatt
     1201 ctgctcaact ctcatgacgg tacctccagc taccagatgc tgccgggtta cttcaggttc
     1261 gtctgccaga acggatgcgt ctgtggtcag tctctggggg aagtgcgtgt tccgcaccgg
     1321 ggaaatgtgg tggacagagt cattgaaggg gcttacgagg tggtgggcgt gtttgaccgg
     1381 atagaggaga agcgtgatgc catgcagtcg ctgctcttac cgccaccggc acgccaggcg
     1441 ctggcacagg cggcactgac ttaccgttat ggtgatgaac atcagcccgt caccactgcc
     1501 gacattctga caccacgacg ccgggaggat tacggtcagg acctgtggag tgcttatcag
     1561 accattcagg agaatatgct gaaaggcgga atttccggtc gcagtgccag aggaaaacgt
     1621 atccacaccc gtgccattca cagcatcgac accgatatta agctcaaccg cgcattgtgg
     1681 gtaatggcag aaacgctgct ggagagcctg cgctgatgca gcatgtctct gaaggcgtga
     1741 ttcaggtacc agaattaccc gacgccccgg aggcgctgcc ggggtgtcgt tccatttctg
     1801 atgatgacct gtgcgcctgg tgtacccgtc tgctttaccg tcccggagaa ctcagtctgt
     1861 gcagactgag tacaggcaat ggcatctggc catccgtctg tgaccggaac ggttacgcgt
     1921 acggctgtcc ggaatttcag cagaatatca ttcatccctg atattaccgg gtctcacggt
     1981 cagtgatgaa cgtgatgttg ccagctcccg acctttactc cctctcattt attcacatta
     2041 caaggatttc atacatgaaa acattgtctc agaacaccac ctcttcggcc tgtgcaccgg
     2101 agactggcct gcaacaactg gttgccacca tagtccctga tgaacagcgc atcagcttct
     2161 ggccgcagca ctttggcctc attccacagt gggtgaccct ggagccccgt atcttcggct
     2221 ggatggaccg tctttgcgaa gactactgcg gtggtatctg gaatctgtac acactgaaca
     2281 acggtggcgc atttatggcg cccgaaccgg atgacgatga tgacgaaaac tgggtactgt
     2341 tcaatgccat gaacggtaac cgcgctgaaa tgagcccgga agccgccggc attgccgcct
     2401 gtctgatgac gtacagtcat catgcctgtc gtacggagtg ttatgccatg acggtccatt
     2461 attaccgg
//
LOCUS       DAZUDJ010000220         2455 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.225, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000220 DAZUDJ010000000
VERSION     DAZUDJ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2455
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.225"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..278
                     /locus_tag="ACHY1N_005251"
     CDS             <1..278
                     /locus_tag="ACHY1N_005251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HFS4047360.1"
                     /translation="GLYRRAAERWAKVMVQLSDDQKRKVAAQKRAECLRKARRTPVSP
                     VNLTEIKQAVNRLHSELGMGFEERRVFRRYKGTGEQNTSGNARSKKC"
     gene            complement(360..584)
                     /locus_tag="ACHY1N_005252"
     CDS             complement(360..584)
                     /locus_tag="ACHY1N_005252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001369651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HFS4047361.1"
                     /translation="MSSKNRTRRTTTRNIRFPNQIIEQINIALDLKGSGNFSAWVIEA
                     CRRRLINEKYSQFVPNKDKHDQSTCSDRFT"
     gene            1011..1517
                     /locus_tag="ACHY1N_005253"
     CDS             1011..1517
                     /locus_tag="ACHY1N_005253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HFS4047362.1"
                     /translation="MAFLLNKSDMASSIGISVQAFDKWGVPPVERRGREVFYDVKTVL
                     EIDRERRQHNQRIPDDEGDLEERLLRARAELTEEQAVAQKLKNQVTEGKLIDTGFCIF
                     ALSKLAMALSSTLDSIPLSMQRQFPDLTPRHLDHLKTLIAKGANQCARAGDKLPDLLD
                     EYIRATTE"
     gene            1489..>2455
                     /locus_tag="ACHY1N_005254"
     CDS             1489..>2455
                     /locus_tag="ACHY1N_005254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HFS4047363.1"
                     /translation="MNISEQQLNNMMSAVTTALQPLIRALPVTPVEWADQNYYLPKES
                     SYGEGEWKTLPFQIAIMNSMGNDQIRTVNLIKSARVGYTKMLLGVVGYFIEHKSRNSL
                     LFQPTDSAAEDFMKSHVEATIRNVPCLKDLSPWLGRKHRDNTLTLKRFSSGVGFWCLG
                     GAAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIK
                     GTCQIEKAANESAHFMRFYVPCPHCGEAQYLKFGDESTPFGLKWEKDSPESVFYLCEH
                     HGCVIHQSELDQSNGRWICENTGMWTRDGLTFFSAAGNEIPPPRSI"
BASE COUNT          651 a          496 c          638 g          670 t
ORIGIN      
        1 aaggactgta ccggagagca gctgaacgat gggcaaaagt gatggtacag ctaagtgatg
       61 accagaaaag aaaagtggcg gcacagaaac gagcagagtg tttgcgtaag gcgcgccgga
      121 ctccggtttc accggtgaac ctgaccgaaa taaaacaagc ggtcaacaga ctacattctg
      181 agttgggaat gggatttgaa gagcggcggg tattccgacg atataaaggg acaggagaac
      241 agaatacgtc cggaaacgcg cggtcaaaaa aatgctaaaa aatatctgag agagttattg
      301 cctgttacca taagaaaaag cgactttagt ggtcgctttt tgtgtcatat ataagtcgtt
      361 taagtaaacc tgtctgaaca ggtgctctgg tcgtgtttgt ctttgttggg tacaaattga
      421 gaatattttt cattaattaa tcttcttctg caggcttcaa taacccacgc tgaaaaatta
      481 cctgaacctt tcaggtcaag agcgatgtta atttgttcaa ttatctggtt tggaaatcgg
      541 atgttgcggg ttgttgttct gcgggttctg ttctttgatg acataatgtt gccccgtatt
      601 cagtgttgct gatttgtatt atctgaagtt gcttttacgc taatttgatg cagatcaatt
      661 aatacgatac ctgcgtaata attgattatt tctcgtggtt tgatggcgta gatgcacgtt
      721 gtgacatgca gatgataatt attatcattt tgcgggtcct ttccggcgat ccgacaggtt
      781 acggggcggc gacctcgcgg gttttcgcta tttatgagat tttttgaggg ggagttgttg
      841 tttaattgtt tggtatatct aattgataag taaggtgaaa ataaaataaa tacaacaacc
      901 ttacgatgtg ttttgatgtc gtcaatgcga aaaatgtcaa tgatatcaaa tggttttgta
      961 aaaacacatg gttgttgtat cgctttttat cgatggctta tggagaggag atggcctttt
     1021 tattgaataa aagtgatatg gcctcctcca tcggtatatc tgttcaggca tttgataaat
     1081 ggggcgttcc tcctgttgag cgtcggggga gggaagtttt ttatgacgtt aaaactgtac
     1141 tggagataga tcgcgagcgg cgacaacaca atcagagaat acctgatgac gagggcgatc
     1201 tggaggaaag gctgcttcgg gccagagctg aactgacaga agaacaggcc gtagctcaaa
     1261 aacttaaaaa tcaggtaacc gaaggtaagc ttattgacac cggattctgt atttttgccc
     1321 tcagtaagct ggcaatggcg ttatccagta cgcttgattc catcccttta tccatgcagc
     1381 gacagtttcc tgatttaaca ccgcgccatc ttgaccatct gaaaaccctt attgctaagg
     1441 gggcaaatca gtgtgcgcgg gcaggggata aattaccgga tttacttgat gaatatatca
     1501 gagcaacaac tgaataatat gatgagcgct gtcacaactg cattacagcc cctgataagg
     1561 gcattgccgg tgacgccagt tgaatgggct gatcaaaatt attatctgcc taaagaatct
     1621 tcatatggtg agggcgaatg gaaaacgctg ccattccaga tcgccatcat gaacagcatg
     1681 gggaatgatc agatccgcac tgttaatctg attaaatctg cccgtgttgg ctatacaaag
     1741 atgttgctgg gggtggtcgg gtattttatt gagcataaat cccgaaacag tctgcttttt
     1801 cagcccacgg attctgccgc tgaagatttt atgaagtctc acgtggaggc gacgattcgg
     1861 aacgtgccat gcctgaaaga cctttcccca tggctgggtc gtaaacatcg tgacaatact
     1921 ctcacgctga aacgcttttc atcgggcgtc ggtttctggt gcctgggcgg tgcagccgcc
     1981 aaaaactacc gtgaaaaatc cgtggacgtg gtctgctatg acgagctttc ctcgttcgaa
     2041 ccggatgttg aaaaagaggg ctcgccaacc ctgctggggg ataagcgtat tgagggctct
     2101 gtatggccaa aatccattcg cggctcgacg cctaaaatca aaggcacctg ccagatcgaa
     2161 aaagcggcca acgagtcggc gcattttatg cgtttctatg tgccctgccc gcactgtggg
     2221 gaggcgcagt atctgaaatt tggcgatgaa tccacgcctt ttgggcttaa atgggagaag
     2281 gacagccccg aaagcgtttt ctacctctgt gaacatcatg gctgcgtgat ccatcagtct
     2341 gagcttgacc agagtaacgg gcgctggatc tgtgaaaaca cgggtatgtg gacccgtgac
     2401 ggcctgacgt ttttcagcgc tgcgggtaat gaaattccgc cgccgcgctc catca
//
LOCUS       DAZUDJ010000221         2449 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.226, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000221 DAZUDJ010000000
VERSION     DAZUDJ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2449
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.226"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(1..602)
                     /locus_tag="ACHY1N_005255"
                     /pseudo
     CDS             complement(1..602)
                     /locus_tag="ACHY1N_005255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311753.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YscQ/HrcQ family type III secretion apparatus
                     protein"
     gene            complement(562..681)
                     /locus_tag="ACHY1N_005256"
                     /pseudo
     CDS             complement(562..681)
                     /locus_tag="ACHY1N_005256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344669.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion protein"
     gene            complement(694..2304)
                     /locus_tag="ACHY1N_005257"
     CDS             complement(694..2304)
                     /locus_tag="ACHY1N_005257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 15 protein"
                     /protein_id="HFS4047364.1"
                     /translation="MKGKSALTLLLAGIFSCGTCQATGAEVTSESVFNILNSTGAATD
                     KSYLSLNPDKYPNYRLLIHSAKLQNEIKSHYTKDEIQGLLTLTENTRKLTLTEKPWGT
                     FILASTFEDDKTAAETHYDAVWLRDSLWGYMALVSDQGNSVAAKKVLLTLWDYMSTPD
                     QIKRMQDVISNPKRLDGVPGQMNVVHIRFDSNSPVMADVQEEGKPQLWNHKQNDALGL
                     YLDLLIQAIDTDTINAEDWQKGDRLKSVALLIAYLDKANFYVMEDSGAWEEDARLNTS
                     SVALVTSGLERLSNLLSKKDSVFVSDLLREAKANELDEPLSTTRLNHLIDKGYERITL
                     QLDLGGESPGYLEKDKHYREADAALLNVIYPANLAKINTRRKEQVLKIVKKLAGPYGI
                     KRYEKDNYQSANFWFNDIKTDTDQNSHAKREKSFIPSTEAEWFFDSWYAKSAAIVYKE
                     SRKEEYLNDSVQFMNRSLAQITGENMIGANGRSVPEMALPESYNYIHKSGTLHEAPSP
                     IIPLNWSKASMTLMLKEMSNLINDEGIK"
BASE COUNT          663 a          529 c          436 g          821 t
ORIGIN      
        1 aaataaccgc ataagccaaa ttatttgaga ttaataaaac atcaccaact tcaatatcaa
       61 caagacttct gtaacatgtt ttactaaatc caattacaaa atgaatggac caatataatg
      121 attttttgtc taacactgga gcgtttccgt attggcagac tgtgacttta tctaaccaaa
      181 gattcaattc ccctgttcat attcttatta gtggttgagc agggttcaat actccatcaa
      241 atactttacc tacgtgcaaa cgattatatt ttagttcagg gtgctttaga tttaacgggg
      301 aactggataa actgagccat tcccctatta acctttccgt ttctggcatt aaagccatcc
      361 cagcgagctc agatgaaatt aagggaaata tttctccaag caatacccat ccagaccagc
      421 tgccactctc ttctgctatc ggtaaccatt tagcactaaa ttcgggcatt aataatgcaa
      481 catcttcgcc attttctttc caattttgaa aagtggtttc aaacgtatga gtgtttcgat
      541 ttactttcct cagaccgaac attaactttc atccttctga tcgttttcga atttgctttc
      601 attttcttgc tcctcataag gctgatgtcg ttgtccttgt cgttcatctt gctcagtcaa
      661 tacccaacgt tgtgctgtaa ctcattatga aaactattta attccctcat cattgataag
      721 gttggacatc tctttcaaca tgagagtcat tgaagctttc gaccaattta gcggaatgat
      781 agggcttggc gcttcatgca aagttcccga cttgtggata tagttatagc tttcgggaag
      841 tgccatttca ggtacactcc tgccatttgc accaatcata ttctcgcctg ttatttgggc
      901 caatgatcta ttcataaatt gcactgagtc attcaaatac tcttcctttc ttgattcttt
      961 ataaacaatt gctgctgatt ttgcatacca tgagtcaaaa aaccattctg cttctgttga
     1021 tggaatgaag ctcttttctc ttttcgcatg tgaattttga tcggtatcgg ttttaatatc
     1081 attgaaccaa aaatttgccg actgataatt atccttctcg tatcttttta taccatacgg
     1141 acctgctagt tttttaacta tttttagaac ctgctctttt cttctggtgt ttatctttgc
     1201 aagatttgca ggataaataa cattaagtaa agccgcatcg gcttctctgt aatgtttatc
     1261 tttttccaga taacctgggg attctccccc taaatcaagc tgtaacgtta ttctttcata
     1321 acctttatct atgaggtggt tcaacctcgt tgttgaaaga ggttcatcca gttcattggc
     1381 tttagcttcg cgtagtaaat cagagacaaa aacagagtct ttcttcgaga gtaagttcga
     1441 caaacgttcc agtccagagg tcaccagtgc aacggaagat gtgtttaatc gggcatcttc
     1501 ttcccatgct ccggaatctt ccataacata gaaattggct ttatccagat aagcaatcag
     1561 cagcgcaacc gattttaatc ggtcaccttt ttgccaatct tcagcgttaa ttgtatcagt
     1621 gtcgattgct tgtataagga gatcaagata aagacctaac gcatcatttt gtttatggtt
     1681 ccacagctgc ggcttgcctt cttcctgcac atctgccatc acgggggagt tgctgtcaaa
     1741 tcggatatgc acaacattca tttgcccggg aactccatcc agtcgtttgg ggttgctaat
     1801 gacgtcctgc atccgcttaa tctggtcggg cgtagacata taatcccaca gggtgagcag
     1861 aacctttttt gcggctacac tatttccctg atctgatact aatgccatat agccccataa
     1921 actatccctc agccagacag catcatagtg ggtttctgcc gctgttttgt catcttcgaa
     1981 agtagaagca agaataaacg ttccccaggg tttctccgtc aacgttaact ttcgtgtgtt
     2041 ttctgttaat gttagcaatc cttgaatttc gtctttggta tagtggctct ttatttcatt
     2101 ttgtaatttg gctgagtgaa tcaaaagacg ataattagga tacttatctg gatttaacga
     2161 taaataactt ttatctgttg ctgcccccgt ggaattaaga atgttaaata cagattcact
     2221 cgtcacttct gcccctgtcg cctggcatgt gccgcacgaa aatataccag cgagcagaag
     2281 agttaatgca gatttccctt tcataaaata ttccatcaat cgtttgttaa aagcgtagat
     2341 aaccacttat ttaacaactt gaaaataagg tgttttacca gggttgttac aaaaggattg
     2401 cattgcgtaa acgcttttta tttacaacaa aatggggaag tattacggc
//
LOCUS       DAZUDJ010000222         2434 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.227, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000222 DAZUDJ010000000
VERSION     DAZUDJ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2434
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.227"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>2434
                     /gene="toxB"
                     /locus_tag="ACHY1N_005258"
     CDS             <1..>2434
                     /gene="toxB"
                     /locus_tag="ACHY1N_005258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="toxin B"
                     /protein_id="HFS4047365.1"
                     /translation="SATGDSLNIMGHLVPVSFIYDIGGVFNGNRISESTDIKNKIKNL
                     KINGDILQHYINTHYLSESQTQKIKDIVDFLGIQDNTKRVKLESDIKHISEVQQPLHS
                     IISRQKEHVKNLLSGLLNEFSNKLRQQGLSLKTNVLSVNNFKASKINSDTVEVTVTDL
                     QGRLYSVDIDTRVIGLTFKEGINSLSEALEHMNIDAIMSVIGLVQYTRMIKTNDNISA
                     IDHAGAVSDIKNIVDKFLGGILTFTNNRVYNPGGISGASLEGFISSGLEVCASRIGGT
                     AGRYLSNVAKVIKLPLLDIGINIWSLYDSSLNHARATTQIEYISTAIDVSFSSINTAL
                     SIGAIAYPPLAIAIVPITIFSHEVKNYAVYVNQINERHKLWLEAEKYLDNGSAKVLSI
                     NKDTGIIDLSNNQVLGNVHLDMRENPPILHGEKSYNSGKNIGSHPDMTDREIMESGAY
                     NFACTKLSDAGEPDIFGWGDKDVCNSMELSESQLANGYSNRQWPSQSPVIPEGIYNTV
                     YLGYGETLRANTEVTLSSTGYFYEIARAYTDDELSEPLLTVCNQRSSVIGGKEPLTII
                     IPALEHGMLGSNLHMIERFKNYNFSISGGKGGIKLMVGGIGDYNIECTPGVRNIISFE
                     QLSRDFNLDLDLSDERKQNFYFHHPSGFYSGKVMSITQKGINSVVGTKQGYDKIRGNN
                     LDNTFSLGNGGGVIYSGGGSNTYFVPATLQHNLHIYISEKSNGNHIILGETHSRLSIE
                     CHFSDDKREFIKMDLYNGGDVILESDTLQKINTFSKNITIQTADGVMANWDDESSTLS
                     VYSIDMIAWRDKN"
BASE COUNT          861 a          349 c          476 g          748 t
ORIGIN      
        1 atccgcaact ggagattcat taaatattat gggacattta gtgcctgtca gttttattta
       61 tgacattgga ggagtcttta atggcaacag aataagtgaa agcacagata taaaaaataa
      121 aatcaagaat ctgaaaataa atggggatat tttacaacat tatataaata cgcattattt
      181 gtcagagtcg caaactcaga agataaaaga tattgtggat tttttaggca ttcaggacaa
      241 cacaaaaaga gttaagcttg aaagtgatat taaacatata agtgaagttc aacagcccct
      301 tcattctatt atctcacggc agaaagaaca tgtaaaaaac ttactatctg gattacttaa
      361 tgagttttca aataagttaa gacagcaagg cctttcactt aaaacaaatg ttctttcagt
      421 taataacttc aaagcatcaa agataaatag tgatactgtg gaggttacag taactgatct
      481 gcaaggaaga ctttatagtg ttgatataga tacaagagtt attggcttaa cttttaaaga
      541 ggggataaat agtttatctg aagcactcga acacatgaat atagatgcaa ttatgtctgt
      601 tattggcttg gttcaatata cacgaatgat aaaaacaaat gacaatatta gcgcaataga
      661 tcatgcagga gcagtatcag atattaaaaa tattgtagac aaatttttag gcggaatttt
      721 aacttttact aataatcgcg tatataaccc tggtggtata tctggtgcct cgcttgaagg
      781 atttatatct tctggtttag aagtgtgcgc gtcaagaata ggtggcaccg ctgggcgtta
      841 tcttagcaat gtggcaaaag taataaaatt acctttgcta gatataggca taaatatttg
      901 gtcattatat gactcttcat taaatcatgc cagagccacc acacaaattg aatatatatc
      961 aacagcgata gatgtatctt tttcatctat aaatactgct ttatcaatag gcgcaatcgc
     1021 atatccacct ttggcaatag ctatagttcc gataactatc ttttctcatg aagtaaaaaa
     1081 ctatgctgtt tatgtgaatc aaattaatga gcgacataag ttatggcttg aagctgaaaa
     1141 atatctggac aatggaagcg caaaggttct aagcattaac aaagatacag gcataatcga
     1201 tttatcaaat aatcaggtgt taggtaatgt tcatttagat atgagagaaa accctccgat
     1261 attacatggt gaaaaatcat ataatagcgg gaagaatatt ggaagtcatc cagatatgac
     1321 tgacagagaa attatggagt ctggagcata caattttgca tgtacaaaac tctcagatgc
     1381 aggtgaaccc gatattttcg gttggggaga taaggatgta tgtaattcaa tggaactgtc
     1441 tgaatctcaa ttagctaatg ggtattctaa ccgccaatgg ccttcacaaa gtccagttat
     1501 tcctgaaggg atttataata cagtatatct tgggtatgga gaaacattgc gagctaatac
     1561 agaagttaca ttgagtagca ctggttactt ttacgagatt gcaagggcat atactgatga
     1621 tgaactatct gagccattat taacagtatg taaccaacgt agtagtgtaa ttggtggaaa
     1681 agaaccatta acaataatca ttccagctct tgaacatggt atgcttggct ctaatctaca
     1741 tatgattgaa cgttttaaaa actacaattt ttcaatatca ggagggaagg gcgggataaa
     1801 attaatggtt ggtggtattg gtgattacaa catagaatgt acccccggtg ttagaaatat
     1861 tatttctttt gaacaattat cacgtgactt caatctggat ttggatttat cagatgagag
     1921 gaaacaaaat ttttactttc atcatccctc tggtttttat tcaggaaaag ttatgagtat
     1981 aacgcaaaag ggcataaatt cggttgttgg tactaaacag ggatatgata agattcgtgg
     2041 taataattta gataatacct tttcccttgg aaatgggggg ggggttatat attctggtgg
     2101 aggaagcaat acatattttg ttcctgctac actacagcat aatttgcata tatatatatc
     2161 agaaaaatca aatggtaacc atattatttt aggtgagaca cactctcgct tatctattga
     2221 atgccacttt agtgatgata aaagagagtt tataaagatg gacttatata atggaggtga
     2281 tgtaatttta gaaagtgaca ctttacaaaa aataaataca ttttcaaaaa atataacaat
     2341 acagacagcg gatggagtta tggcaaactg ggatgatgaa tcaagtactc tgtctgttta
     2401 ttcaatagat atgattgcct ggagggataa aaat
//
LOCUS       DAZUDJ010000223         2388 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.228, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000223 DAZUDJ010000000
VERSION     DAZUDJ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2388
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.228"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..276
                     /locus_tag="ACHY1N_005259"
     CDS             <1..276
                     /locus_tag="ACHY1N_005259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310216.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6645 domain-containing protein"
                     /protein_id="HFS4047366.1"
                     /translation="VNLMHHRKAGNTKLGEFGDYGNDWQTLELVFTAGGATVTPKLNG
                     VAGPAFQVIKDSLTLGLNALTLTDVTKNAAYGVEIESLMLEINAPAA"
     gene            569..784
                     /locus_tag="ACHY1N_005260"
     CDS             569..784
                     /locus_tag="ACHY1N_005260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0020002 - host cell plasma membrane
                     [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA];
                     GO_process: GO:0019835 - cytolysis [Evidence IEA];
                     GO_process: GO:0044659 - viral release from host cell by
                     cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II holin family protein"
                     /protein_id="HFS4047367.1"
                     /translation="MHQMEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGS
                     LLFGLLTYLTNLYFKIREDRRKAARGE"
     gene            789..1133
                     /locus_tag="ACHY1N_005261"
     CDS             789..1133
                     /locus_tag="ACHY1N_005261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdfR family protein"
                     /protein_id="HFS4047368.1"
                     /translation="MKKKYELGVKGINNYPDKITVTVALEIGGYPSLLLPDVAISLDR
                     TEGATLEFYEAEAKKQAKQFFMDVAAGLCEGDGPLPEKRPVILEAQDVLITYRGKLPG
                     IITGSLKTPPLA"
     gene            1184..1717
                     /gene="rrrQ"
                     /locus_tag="ACHY1N_005262"
     CDS             1184..1717
                     /gene="rrrQ"
                     /locus_tag="ACHY1N_005262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HFS4047369.1"
                     /translation="MNAKIRYGLSAAVLALIGAGASAPEILDQFLDEKEGNHTTAYRD
                     GAGIWTICRGTTRVDGKPVVPGMKLSKEKCDQVNAIERDKALEWVERNIKVPLTEPQK
                     AGIASFCPYNIGPGKCFPSTFYRRINAGDLKGACEAIRWWIKDGGRDCRIRSNNCYGQ
                     VSRRDQESALACWGIDR"
     gene            1873..2055
                     /locus_tag="ACHY1N_005263"
     CDS             1873..2055
                     /locus_tag="ACHY1N_005263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310767.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047370.1"
                     /translation="MGKYKRILLRLTMKNGLELKAPVTDDVSRALAFAIKWVAVGIAV
                     SPMLYGLAKLVIALKS"
     gene            2068..2199
                     /locus_tag="ACHY1N_005264"
     CDS             2068..2199
                     /locus_tag="ACHY1N_005264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047371.1"
                     /translation="MSDKLITLAKILCVIVGISFSLMLVAICFSTAWRVLTLSWLVG"
     gene            2207..>2388
                     /locus_tag="ACHY1N_005265"
     CDS             2207..>2388
                     /locus_tag="ACHY1N_005265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310766.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HFS4047372.1"
                     /translation="MNRVLCVVIIVLLVACGVLSLGLNHYRDNAITYKAQRDKKASEL
                     KLANVTITDMQVRQRDV"
BASE COUNT          611 a          490 c          700 g          587 t
ORIGIN      
        1 gtgaatctga tgcatcacag gaaagccgga aacacgaagc tgggggagtt cggcgattac
       61 ggtaacgact ggcagacgct ggagctggtg ttcaccgccg gcggtgccac ggttactccg
      121 aaactgaatg gagtggctgg cccggcattc caggttataa aagacagtct gacactggga
      181 ctgaatgcgc tgacgctgac ggatgttaca aaaaatgcag cgtatggcgt tgagatagaa
      241 agtctgatgc tggagataaa tgcaccggca gcataataaa aaaacagcca gtactgactt
      301 tcgtcggaga agtactggct aagaaggata gttgggtttc acatgatact tatatctggc
      361 agtacatttt ctgacagaca gtgatgggtg ttgtcaagat attgtgtcat ttataacctg
      421 aatcaggggg gggagccgga atgttatctg gcatttttag cagagcctga atgccataat
      481 cacggctccc ggcgttggcc gtcagtgggc gacactggcg gctttttgtt ttcctttact
      541 ttcattttct gtcggcggtg acggagacat acatcagatg gaaaaaatca caacaggtgt
      601 gtcatacacc acgtcagcgg tggggacggg atactggtta ctgcagctgc tggacaaagt
      661 ctctccgtcc cagtgggtgg caatcggtgt gctggggagt ctgctgtttg gcctgctgac
      721 gtatctgact aacctgtatt tcaaaatcag agaggaccgt cgtaaggcgg cgcgggggga
      781 gtaaagcgat gaagaaaaaa tacgaactgg gtgttaaagg gataaataat tacccggata
      841 agattactgt tactgtggca ctggaaattg gtgggtatcc gtcactgttg ttgccagatg
      901 tggcgattag tcttgaccgt actgaaggtg ccacgctgga gttttacgaa gctgaggcga
      961 aaaagcaggc gaagcagttt ttcatggatg ttgctgccgg gttatgtgaa ggggatggtc
     1021 cgttgccgga aaagcgcccc gtaattttag aggcgcagga tgtgttgata acctacagag
     1081 gaaaactacc gggaataatt actggttctc tgaagactcc accgctggcc tgaagactta
     1141 acatatccag ggatttgaaa tcgataaacc ctgataaata tccatgaacg caaaaatcag
     1201 atacggcctg tcggctgccg ttctggcgct gattggtgca ggggcgtctg cgcctgaaat
     1261 cctcgaccag tttcttgacg aaaaagaagg taaccacacc acggcatacc gtgatggtgc
     1321 ggggatctgg accatctgcc gcggtaccac ccgagtggat ggtaaacctg tcgtcccggg
     1381 catgaagttg tcgaaggaaa aatgcgacca ggttaacgcc attgaacgtg ataaggcgct
     1441 ggagtgggtg gagcgcaata ttaaagtacc gctgaccgaa ccccagaagg cgggtatcgc
     1501 gtcattttgt ccttataaca ttggccccgg taagtgtttc ccgtctacgt tttacagacg
     1561 gattaatgca ggtgatctaa aaggtgcctg cgaagcgatt cgctggtgga ttaaggacgg
     1621 tggcagagac tgccgtattc gctcaaacaa ctgctacggt caggtttcac ggcgtgacca
     1681 ggagagcgcg ctggcgtgct ggggaattga cagataagca gaatattttg ctgaaaaatg
     1741 cggtttgctc acactggcgg ataacacgaa atcctgcgaa ctggcaaaaa ctaagtgaat
     1801 aaaagtaaaa ccccgtttgt tggccgcaaa cggggttttg tgtttctgac cttgagtaag
     1861 gcaagggaga acatgggaaa gtataaacga attctgttga gattgactat gaaaaacggc
     1921 cttgaactga aagcgcctgt aactgatgac gtcagcagag cgctggcttt tgctattaag
     1981 tgggtggcgg tcggtattgc tgtgtctccg atgctgtatg ggctggcaaa actggtcatt
     2041 gcgttgaaat cgtgaagagg attaagcatg tcagacaagc tcataacgct ggcgaagatc
     2101 ctctgtgtaa tcgtcggcat ttcattttca ctaatgctgg ttgctatttg cttttccact
     2161 gcctggcgcg tcttaacttt gtcatggctg gtggggtgag ggggatatga accgtgttct
     2221 gtgtgtggtg attattgtcc tgctggtagc ctgtggtgtg cttagtctgg ggctgaatca
     2281 ttaccgcgat aacgccatta cctacaaagc gcaacgcgat aaaaaagcca gtgagctgaa
     2341 gctggcgaac gtgacaatta ctgatatgca ggtacgccag cgtgatgt
//
LOCUS       DAZUDJ010000224         2375 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.229, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000224 DAZUDJ010000000
VERSION     DAZUDJ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2375
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.229"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..1226)
                     /gene="wzx"
                     /locus_tag="ACHY1N_005266"
     CDS             complement(<1..1226)
                     /gene="wzx"
                     /locus_tag="ACHY1N_005266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_099459345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O103 family O-antigen flippase"
                     /protein_id="HFS4047373.1"
                     /translation="MEKLNFAKVTILSGVVTCFRLICGLLISKVVAIYTGPIGIANLG
                     QLQNFVAFINGFISSQVSQGVNRYSAENQGDYENACFYWRASIKLSFIACCFIISTGV
                     LFSSKISEYLFYQSDLYWLIIIALCALPLNIVNNIFLGVLNGLNEYNRFFLANVLAIS
                     SSLLSMVGLVYFFGLKGALVSASLNNAVAGVWLITIIIKRPWFKFKYWVGHTPRHNIT
                     QMKNYFYMGVIGALTGPISMIVVRTILTNNFSLEDAGYWQAVNRISEAYLAVLTTALT
                     VYYFPKTAAARRYSEYITLLKTGACIVVPLALSMALTIYGLKDFIISILFTADFIRAR
                     ELFLFQNIGDFLRICSWLFATILLAKGYFKINAILEVMFSIIFPVLVKFLIINFGLNA
                     VSIAYSITYALYFIVV"
     gene            complement(1214..2320)
                     /locus_tag="ACHY1N_005267"
     CDS             complement(1214..2320)
                     /locus_tag="ACHY1N_005267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HFS4047374.1"
                     /translation="MIDFLNLKRINAQYEVELKDACSRVIDSGWYIMGTELKTFEEKF
                     ANWCGVKHVIGVANGLDALILVLRAWKEMGKLNDGDEIIVPANTYIASVLAITENNLV
                     PVLTEPDPLTFNLSAGGIRKVITGKTKAILPVHLYGQISPMAEIMEIAAEFGLLVLED
                     CAQAHGSSIDGRKAGSWGHAAGFSFYPGKNLGALGDAGAITTSDDQLADILTAIRNYG
                     SHEKYKNKYQGLNSRLDEMQAAFLNVKLKYLDRENKLRRAIAKKYIEEIKNPLISLPV
                     IAGNEMSHVWHLFVIRTSERDSLQKHLKTEGITTLVHYPIAPHNQEAYKEYSFLSLPL
                     TERIHREVLSLPMDPTMSIDDINMVIEAINRWKS"
BASE COUNT          815 a          487 c          334 g          739 t
ORIGIN      
        1 cacaccacta taaaatacaa tgcataagtg atgctgtagg caatactaac ggcatttagt
       61 ccaaaattaa ttatcaaaaa ctttaccaat actggaaaaa ttattgaaaa catcacctcc
      121 aatatagcat ttattttaaa atatcccttt gctaacaata tagtggcaaa cagccaacta
      181 caaatccgca gaaaatcccc gatattttga aataaaaaaa gctcccgagc acgtataaag
      241 tcagccgtga acaagatact aattataaaa tctttcaagc cgtagatggt taaagccatg
      301 ctcaacgcga gcggtacaac aatacaagcc ccggtcttta aaagagttat atattcgcta
      361 tatcttcttg cggctgcagt ttttggaaaa taataaactg tcaatgccgt agtaagaaca
      421 gccagataag cctcagaaat tctatttaca gcttgccaat atccggcatc ctctaaagaa
      481 aaattattag tgagaatagt tcgaacaact atcatcgaaa taggtccagt taacgctcca
      541 atcaccccca tataaaagta atttttcatc tgagtaatgt tatgccgagg agtatgtccc
      601 acccagtatt taaatttaaa ccatggtctt ttaattataa tagtaataag ccagacacct
      661 gcaaccgcat tatttaatga tgcagacact aatgcgcctt tgaggccaaa aaaataaact
      721 aagcccacca tagataacaa cgatgaggat atagctaaaa cattcgcaag gaaaaatcta
      781 ttatattcat ttagtccatt taaaacccct aaaaatatat tgtttactat attaagagga
      841 agagcgcata gagcaattat aattaaccaa tacaaatcac tttgataaaa taagtattct
      901 gatattttac tggaaaaaag cacccccgta cttataataa aacaacaggc tatgaaggat
      961 aatttaattg atgcacgcca ataaaaacat gcattttcgt aatcaccttg attttctgct
     1021 gaatatctat taactccttg tgaaacttgt gatgaaatga atccatttat aaaggccaca
     1081 aaattttgca attgtcccaa atttgctatt ccaattggac cagtataaat tgcaacaact
     1141 tttgaaataa gaaggccaca aattagtcta aagcatgtta ctacaccact gagtatcgta
     1201 acttttgcga aatttagctt ttccatctat taatcgcttc aattaccata ttaatatcgt
     1261 cgatgctcat tgtcggatcc attggcagcg ataagacttc tctatgtatt ctctcagtta
     1321 aagggagaga taaaaaacta tattctttat atgcttcttg attatgaggc gctattgggt
     1381 aatgcactaa tgtagtaata ccttcagttt tcaaatgttt ttgcaaagaa tcacgctctg
     1441 aagttctgat aacaaaaaga tgccatacat gagacatttc attgccagca attacaggca
     1501 gtgaaattag tggattcttg atttcttcaa tatatttttt agctattgca cgtcttaatt
     1561 tattttccct atcaagatat tttaacttga cattcaaaaa tgccgcctgc atttcatcca
     1621 atcgactatt taagccttga tatttgtttt tatatttttc atgagaacca taatttctaa
     1681 tagctgtcaa aatatctgca agttgatcat cactcgttgt tatcgcacct gcgtcaccta
     1741 aagcgccaag attttttcct ggatagaaac tgaatccagc tgcatgaccc caactgccag
     1801 ctttgcgtcc atcgatagag gaaccatgag cttgagcgca atcctctaaa accaataaac
     1861 caaactctgc cgcaatctcc attatttctg ccattggaga tatttgtcca tacaaatgca
     1921 ctggcaaaat tgcttttgtt ttccctgtaa ttactttacg aatcccaccc gcacttaagt
     1981 tgaatgtcaa aggatctggt tcagtcaata cagggactag attattttca gttattgcca
     2041 aaacagatgc aatatatgta ttggcaggta caataatttc atctccgtca tttaatttcc
     2101 ccatttcttt ccaagcccga agaacaagga ttagtgcatc taagccattg gcaacaccaa
     2161 taacatgctt aactccacac caatttgcaa atttttcctc aaatgtcttt aactccgtcc
     2221 ccataatata ccaaccagaa tcaataactc tggagcaagc atcttttaat tccacttcat
     2281 attgagcatt tattcttttt aaattcaaaa aatcaatcat tttctttccc ctcaaaaata
     2341 tttactatat ttttctctta aacgaataaa atttt
//
LOCUS       DAZUDJ010000225         2285 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.230, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000225 DAZUDJ010000000
VERSION     DAZUDJ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2285
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.230"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(94..1632)
                     /gene="cadC"
                     /locus_tag="ACHY1N_005268"
     CDS             complement(94..1632)
                     /gene="cadC"
                     /locus_tag="ACHY1N_005268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylation/transport transcriptional
                     activator CadC"
                     /protein_id="HFS4047375.1"
                     /translation="MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHS
                     GEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMV
                     PVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
                     VWFFFLLSLGICVALVAFSTLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLS
                     YAIGVGDLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSI
                     KLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQRMQETLQQILPHRG
                     ALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPL
                     DEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSW
                     LNYVLLGKVYEMKGMNREAADAYLTAFNLRPGANTLYWIENGIFQTSVPYVVPYLDKF
                     LASE"
     gene            complement(1892..2006)
                     /locus_tag="ACHY1N_005269"
                     /pseudo
     CDS             complement(1892..2006)
                     /locus_tag="ACHY1N_005269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001218818.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
BASE COUNT          669 a          461 c          484 g          671 t
ORIGIN      
        1 cggcaaataa attgccgcaa catattatac caatagaaac atacaaaaac tcaacaacaa
       61 atattcccga gcataaatca acccgggagt tacttattct gaagcgagaa atttgtcgag
      121 ataaggtaca acataaggaa cagaagtctg gaatatacca ttttcaatcc agtaaagggt
      181 gtttgcccct gggcgtaaat taaaggcggt gagatatgca tcagccgctt cccggttcat
      241 ccccttcatt tcataaacct tgccaagcaa cacataattt agccaggaca tttcaagatc
      301 aatgccagta tttatcgcct ggtaagactc atctgtttta ccttttacca gagcactgac
      361 cgcttttatt tgatatataa tggacaggtt attcaattcc ggcagtgtaa caatgttgtc
      421 tatttctgtg ttcagtgctg ctaattgttt ttcatctaaa ggatgttgag aatggcgcac
      481 gatatcaact aatgcttttt ctgctctcgc gtaggtaaat tctggggatg attgaacaat
      541 ctcacctaat aattcactgg cacgattcaa tgatttatca tcgccatgca gtaaataatc
      601 atgtgcctga taaaaattag ttaataacgc accacgatga ggcaatattt gctggagcgt
      661 ctcctgcatt cgttgtggcc acggttggtt taacgctttt gataaactct ccagtaaatc
      721 attttgaatc gccagctgat taccgttagt gatgacataa cgtttatcca gcatggttga
      781 accatctgca ttgtctacca attttatcga cataaagcat tgttgagcac ggtattggcg
      841 ctgattaaca aacgcaatag ataatgtttt accggaactg ctcggttcat caatgttgta
      901 gttgattttg tcatgcacca taaaggtgga gaaggtgtta agtgatgtcg ccaccaaatc
      961 acccacgcct atcgcgtaag agagctgata cggggaactc cagctgttac aacttttatt
     1021 taccatatta atgtcaatat cgcgtggatt gagcaaaata cgcgatttgc tcataggaag
     1081 acgtgtatca agagttgaaa acgctaccag tgctacacag atacctaacg acaacaggaa
     1141 aaaaaaccat acccaaaagg tagtgaatcg tttgctttta actggggatt gttcaggtgg
     1201 cgttgcggtg ttttgaatgt taagactgtg ggagggagaa tctgtggcag gaaccgcctc
     1261 tggtataggg ggaggcgaag atagcattat ttcctctccc tcttcttcgc tgtaccagat
     1321 aaccggcacc attaatttat agccgcgctt tggtacagta gcgatataga caggactatc
     1381 ttcatcatta tcttttaatg acttacgtag ttctgagata ctctgcgtca caacatgatt
     1441 ggtgacaata cttctcttcc agacattatc gataagttca tccctgctaa gtacttcgcc
     1501 actgtgttga gcaaagaaaa ccagaagatc gattaatctc ggctcaaggg taagttgacg
     1561 cccattgcgg ctaatttggt ttatggacgg agtaacaagc cattcgccaa cgcgaactac
     1621 aggttgttgc ataatagaaa ctcattcgaa aagggaatga tgcaatgata attgccacaa
     1681 cctattttta ccatctatag atgggtttat ttacatatta ttggtgaatg caagacgtta
     1741 tttttaccag ccataaactt cttgattaca tagtattacg aaaggatttt actgagaacc
     1801 agaagtaata ttccttacca tcaaaattca tcatctttgc caaagaaaaa tgttcagaaa
     1861 ataatccatg gaaaattgtc cggagcgctt actattttaa tggattgtta gtctttgcat
     1921 gagcaagcgg actgatacat ttctctttgt tctcattcag aaaatctcat cagtcggcgt
     1981 tcagaccggt gttgtgcttt atggatgcgt tacgctcctg atgacgtcat ttgacgttca
     2041 acaacatcac ggggccgcac gacatttcac gtcagttagt gctatcgctc aggaacaaat
     2101 tttcccgaat tgggatatgc ccgcaaattg ctggtgatgt ggggagaatc tggttgagtt
     2161 cgggagaatt gatttggagg cagaacgctt aaattgtggc gtccagaaac gaaaaacgga
     2221 cctccgtgga ggtccgttga tatgaatttg gtgccggact cggaatcgaa gaatgcttct
     2281 atcat
//
LOCUS       DAZUDJ010000226         2284 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.231, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000226 DAZUDJ010000000
VERSION     DAZUDJ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2284
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.231"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..701)
                     /locus_tag="ACHY1N_005270"
     CDS             complement(<1..701)
                     /locus_tag="ACHY1N_005270"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFS4047376.1"
                     /translation="MTLKRACSLLTVKSFSEDERVITGIASTPSPDRDGDILEPEGAE
                     FGSTIPFLWQHDHSRPVGQCTVRRVREGLEITAMLVKPEPGMPSQMAARLDEAWAAIK
                     TGLVRGLSVGFRPHEYTFLDGGGLHFLRWELMEVSAVTVPANAECTIRTIKSYDRPFS
                     AASGNRKPVVKIASSAGAAAQSTTVFHKEKTIMNIGEQIKSFENKRAALAASLEEVMT
                     KAAEEGRTLDVEEEE"
     gene            complement(765..>2284)
                     /locus_tag="ACHY1N_005271"
     CDS             complement(765..>2284)
                     /locus_tag="ACHY1N_005271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HFS4047377.1"
                     /translation="GSPTFGESCAPWVFDLVAALFGSYDAQTGVRHIKEVFILIPKKN
                     SKSTLAAGIMMTALLLNWRQAAGYTILAPTVEVAANAFNPARDMVRRDDDLDDLCQVQ
                     THIRTITHRVTDTTLKVVAADPNTVSGIKSVGTLIDELWLFGKQYKAEDMLREAIGGL
                     ASRPEGFVVYTTTQSNEPPAGVFRQKLQYARDVRDGKIHDPHFLPVIFEHPPEMVESG
                     AHLLMENLAMVNPNLGYSVDEAFLYREYRKAREAGEEAFRGFMSKHANVEIGLALRSD
                     RWAGADFWEQQGRRVSLDDILQRADVVTVGIDGGGLDDLLGMYVTGRDRETREWLGWG
                     HAWVHETAVVRRKSEASRFQDFVACGDMTIVRRVGDDTAEVAEYVRRIHEAELLDHIG
                     IDPSGVGQILDSLAEAGIPDESVVGISQGWKLGGAIKTTERKLAEGVLIHGDQPLMAW
                     CVGNARVEPKGNAILITKQASGRGKIDPLMALFNAVSLMSLNPEPKKKAYEVFFI"
BASE COUNT          484 a          750 c          573 g          477 t
ORIGIN      
        1 tgctcttcct cctccacatc cagcgtgcgc ccttcctctg cggctttggt catgacctcc
       61 tcaagggagg ctgccagcgc tgcacgcttg ttttcaaaac ttttaatctg ttcgccaata
      121 ttcattatgg tcttttcctt atgaaaaacg gttgttgact gtgccgcagc gccggcagaa
      181 gatgcgattt tcaccaccgg tttccggttg ccggacgcgg cagaaaacgg gcggtcgtaa
      241 gatttaatgg tccggatggt gcattccgca ttcgcgggca cggtgacggc agacacctcc
      301 atcagttccc agcgcagaaa atgcagtccg cctccgtcca gaaaggtgta ttcatgggga
      361 cggaagccca cggacagccc cctgaccagc ccggtcttaa tggcagccca ggcctcatcc
      421 agccgggctg ccatctggga gggcatcccc ggctccggct tcaccagcat tgccgtgatt
      481 tccagccctt ccctgacccg acgcaccgta cactggccta cagggcggga atggtcatgc
      541 tgccagagaa acgggatcgt actgccaaac tcagccccct ccggctccag gatgtcacca
      601 tcccgatccg gagaaggcgt tgacgcaatc ccggtgatca cccgttcatc ctcactgaag
      661 gatttcaccg tcagcaggga acaggcccgt ttaagagtca catcagcctc ctgaaaataa
      721 aaaaaccgcc gcagcggttc atgatggtta cagggtgagc agggttatat gaaaaaaacc
      781 tcatacgctt tctttttcgg ttccggattc agggacatca gggacaccgc attgaagagc
      841 gccatcagcg ggtcaatttt tccccgtccg ctggcctgtt tggtgataag aatggcgtta
      901 cctttaggct ccacccgggc attaccgaca caccaggcca tcaggggctg atcaccgtga
      961 atcagcaccc cttcagccag tttgcgctcg gtggttttga tggccccgcc cagcttccag
     1021 ccctggctta tccccaccac actctcatcg gggatcccgg cttccgccag tgaatccaga
     1081 atctgcccca cacctgacgg gtcaataccg atatgatcca gtaactcagc ctcatgaata
     1141 cgacgcacat actccgccac ttccgccgtg tcatccccga cccgacggac aatcgtcatg
     1201 tctccacagg ccacaaaatc ctgaaaccgg gatgcctcac tcttccgtct gaccaccgcg
     1261 gtttcatgca cccaggcatg gccccagccc agccattcgc gggtttccct gtcacggcca
     1321 gtcacgtaca ttcccagcag atcatccagg cccccgccgt caatccccac cgtcaccaca
     1381 tcagcgcgct gcaggatatc gtccaggctg acgcgcctgc cctgctgctc ccagaaatcc
     1441 gcgcccgccc agcggtcaga acgcagggca agaccgattt ccacattggc gtgttttgac
     1501 atgaagccac gaaatgcttc ctcaccagcc tcccgggctt tacggtactc ccggtacaga
     1561 aaggcctcat ccaccgaata accgagattc gggttaacca tggcgaggtt ttccatcagc
     1621 aggtgagccc cgctttccac catttcagga ggatgctcaa aaatcaccgg cagaaagtgc
     1681 ggatcatgaa ttttgccgtc acggacatcc cgggcatact gcagtttctg tctgaacacc
     1741 ccggcgggcg gttcattcga ctgggtggtc gtatacacca caaacccttc cggacgggag
     1801 gcaagcccgc cgatggcttc acgtagcatg tcttccgcct tgtactgctt gccaaacagc
     1861 cacagttcat caatcagtgt ccccacggac ttgataccgg acaccgtatt cggatcggct
     1921 gccaccacct tcagggtggt gtccgtcacc cgatgggtga tggtccggat atgtgtctgc
     1981 acctgacaga ggtcatccag atcatcgtcc cgtcgtacca tatccctggc agggttgaag
     2041 gcgttagccg ccacctccac ggtcggggcc agaatggtgt agcccgccgc ctgccgccag
     2101 ttcagtaaca gcgccgtcat catgatcccc gcagccagcg tggacttact gtttttcttg
     2161 gggataagga taaacacttc cttgatatgg cgaacaccgg tctgcgcatc gtaggagcca
     2221 aacagggccg ccaccaggtc aaacacccac ggtgcacagg actccccgaa tgtcgggcta
     2281 cccg
//
LOCUS       DAZUDJ010000227         2259 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.232, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000227 DAZUDJ010000000
VERSION     DAZUDJ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2259
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.232"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..388
                     /locus_tag="ACHY1N_005272"
     CDS             <1..388
                     /locus_tag="ACHY1N_005272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4047378.1"
                     /translation="PLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAVRR
                     AEADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFALDM
                     AATLVVPFTGDGRDAAEILRTLPPLK"
     gene            complement(627..707)
                     /locus_tag="ACHY1N_005273"
                     /pseudo
     CDS             complement(627..707)
                     /locus_tag="ACHY1N_005273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            789..1154
                     /locus_tag="ACHY1N_005274"
     CDS             789..1154
                     /locus_tag="ACHY1N_005274"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047379.1"
                     /translation="MSRSAKPRKRKPAPQRSKLPRYVVKLHDDDFFDEEDAEALRFDN
                     FDDAVECCADLNIPFFVDAGNKKLVFWFVRVDDEGYPEIARCTEREFATILAGISAGG
                     MYCPECGTVHWPDGVPPPF"
     gene            1154..>2259
                     /locus_tag="ACHY1N_005275"
     CDS             1154..>2259
                     /locus_tag="ACHY1N_005275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013747467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HFS4047380.1"
                     /translation="MLPRFADIFQQGNRWLNWLEKQPEGSVRPVVIESVTKIMACGTT
                     LMGYTQWCCSSPDCSHIKKVCFRCKSRSCPHCGVKAGAQWIQYLLSLVPDCPWQHIVF
                     TLPCQYWSLVFHNRRLLAEMSRIAADVIQEICRQADVVPGIFTVIHTWGRDQEWHPHI
                     HLSTTTGGVTSDHTWKNLHFYARKVMSMWRYRITRLLSRKYPDLVIPDALAAEGSSKR
                     DWNRFLDSHYRRGWNVNVSRVMDNATHVAVYFGSYLKKPPVPMSRLEHYAGQDEIGLR
                     YNSHRTKREEYLVMSGDEFMERFSWHVADKGFRMVRYYGFLSPVKRRLLEDVVYVITE
                     TVRKTAMQIRWRGMYQRLLKVDPLKCILCGGQMR"
BASE COUNT          534 a          559 c          662 g          504 t
ORIGIN      
        1 tccgctgaca gatataagct atgtcaggca gatggaaagc tggatgatca ccacccggcc
       61 ccgtcgtcgt gaaccattat gggccgtgac tgacgaaacc atgcgcaact ggctgaagca
      121 ggctgtcaga cgggccgaag ctgacggggt acacttttcg attccggtca caccacacac
      181 cttccggcac agctatatca tgcacatgct ctatcaccgc cagccccgga aagtcatcca
      241 ggcactggct ggtcacaggg atccacgttc gatggaggtt tataccagag tttttgcgct
      301 ggatatggct gccacgctgg tagtgccttt cacaggtgac gggcgcgatg ctgcagagat
      361 cctgcgtaca ctgcctcccc tgaagtgaca gcatacgctc ttccttatat aagcagtggt
      421 cagcagaaca gacataacat aagctggagc aggtagataa gctgtagtga gtaaaccatg
      481 ttttatgaag ggagcaatgc ctcagcatca ggttacgggg tgactcacgt aagggacagg
      541 cagatggcag ctcagccaca ggcagcactg caggaaactg aatataaacg taagcgtaca
      601 gcgagggccg tattgacggg gatgtgttat tcagctggca gtgctatgcg ccacggaagc
      661 agttcgctga cccggttgac cggccagtct gctatgacgc cgagtaggca gcctggcggc
      721 tgcggcttgt catggcctga aattaccgtt ataaaaacag acaatatcat tgtctttcag
      781 gtagttatat gtcccgttca gctaaacccc gtaaacgaaa acctgcccct caaagaagca
      841 aacttccccg ctatgtcgtg aagcttcacg acgatgactt ctttgacgaa gaagacgcag
      901 aagctctgcg ctttgataat tttgacgatg ccgttgagtg ctgcgcagac ctgaatattc
      961 ccttctttgt ggatgccgga aacaaaaagc tggtcttctg gtttgtacgt gttgatgacg
     1021 aagggtatcc tgaaatagcc cgctgcacgg agcgggagtt tgcgaccatt cttgccggta
     1081 tcagcgccgg cggcatgtac tgcccggagt gtggcacggt tcactggccg gacggagtcc
     1141 ccccgccctt ctgatgcttc cccgttttgc cgacattttt cagcagggaa accgctggct
     1201 taactggctg gagaaacaac cggaaggttc agtgcgtccg gtagtcattg agtctgtgac
     1261 aaaaatcatg gcctgcggga ccacgctgat ggggtacaca cagtggtgct gttcatctcc
     1321 ggactgcagc cacataaaaa aggtctgctt ccggtgtaaa agtcgctcct gcccgcactg
     1381 cggagtgaag gctggcgcac agtggataca gtatctgctg agtctggttc ccgactgtcc
     1441 gtggcagcat attgtgttca cacttccctg ccagtactgg tccctggtgt tccacaaccg
     1501 gaggttactg gcagagatga gccgcattgc tgcggatgtg atacaggaaa tctgccgcca
     1561 ggcagatgtg gtgccgggga tattcacggt gatccacaca tggggacgtg accaggagtg
     1621 gcatccgcac attcacctgt cgacaacgac cggcggcgtg acatcagacc acacctggaa
     1681 aaaccttcat ttttacgccc gtaaggtgat gagtatgtgg cgttaccgga taacgcggtt
     1741 actgtcacgg aaatatccgg acctggtgat accggatgcg ctggcagcag aaggaagcag
     1801 taaacgggac tggaatcgct tcctggacag tcattaccgg cggggctgga atgtcaacgt
     1861 atcccgggtg atggataacg ccacacatgt ggcggtgtac ttcggctctt acctgaaaaa
     1921 accgccggtg ccgatgagcc gtctggagca ctatgctggt caggatgaaa ttggtctgcg
     1981 ttacaacagt caccggacaa aacgggaaga atacctggtg atgagtggtg atgagtttat
     2041 ggaaaggttc tcctggcatg tggcggataa ggggttccgt atggtgaggt actacggttt
     2101 cctgagtccg gtgaagcgcc ggttactgga agatgttgtg tacgtcataa cggagacggt
     2161 gagaaagacg gcgatgcaaa tcaggtggag agggatgtat cagcggttac tgaaggttga
     2221 cccgctgaag tgcatcctgt gcggaggtca gatgcgttt
//
LOCUS       DAZUDJ010000228         2256 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.233, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000228 DAZUDJ010000000
VERSION     DAZUDJ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2256
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.233"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            586..1359
                     /locus_tag="ACHY1N_005276"
     CDS             586..1359
                     /locus_tag="ACHY1N_005276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4047381.1"
                     /translation="MTKHMDIHCQTRIFNSINHDTKYKICIFTPKNIKKNNATLYILD
                     GNSANNYISDILPVIDALPNPPVLVTLGYESWNNLSIHRRAYDYTPDGENAIVDNSKP
                     AWIYFTGGGSQSFRELLLTQIMPWVSTIAPNSSRIGIWGHSLGAIFVLDCLKNNSCFN
                     YYYISAPSLLWQNERIIKIIKDDISESKHTKSICLLNGNLSLDYSASLYPEAIKAESV
                     LRNILTEKYSNFSIVQFPELNHQETFSAALWNSIIHFSI"
     gene            complement(1711..2124)
                     /locus_tag="ACHY1N_005277"
     CDS             complement(1711..2124)
                     /locus_tag="ACHY1N_005277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HFS4047382.1"
                     /translation="MAKVFTQEEREKIKGQVVELVRRSGRETLRQLEAKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRAKLKKPVVVDPDLIWSLPDG
                     EIRRYDRQLNIICSECRNSEVMQRVLIFYTGVMME"
     gene            complement(2140..>2256)
                     /locus_tag="ACHY1N_005278"
     CDS             complement(2140..>2256)
                     /locus_tag="ACHY1N_005278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
                     /protein_id="HFS4047383.1"
                     /translation="KSDVQKWERVCAALRELNKHRDIVRQITDSSRRVVSEK"
BASE COUNT          674 a          497 c          383 g          702 t
ORIGIN      
        1 ttcggcacgt aagaggctaa cctagatttg ccgttcatag attgagcctc agattaatgt
       61 taagcgtctt gcaggacgcg taatgttaac tggggctttt ctctatctgc cgttggtgtt
      121 catgcccgag gcagatagcc tcaagcaccc gcagctattc tacttaactt cccattacct
      181 cgccaatatg aaatcggtca gaaagacaga cgtcccataa ggacaacaac ggaaaaagag
      241 attttgcttg atgctattta cctctgcacc atgaagttgc gccaaaatcc cagtggtgat
      301 aacaggaatt tggttgttgg tgattgggga aagaagtacg ttagactgtg ggttagttca
      361 ttgacatgat agttacctgc cttcaatttc ctaagcaagc gatgtaaacg ataatcaata
      421 tcaaatgtat tgacaggtaa aataataacg atgtaccttt gctgataaca tatatcagtc
      481 ttaaatcata atggaggtag ataaaataac taaacacaca caacaaattt tttatcagtg
      541 acatagcata tcttaagcat cctttaatgc tcatggggag aacgcatgac taaacatatg
      601 gacattcatt gtcaaacacg catatttaac tcaattaacc atgacaccaa atataaaata
      661 tgtattttta ctccaaaaaa cattaaaaaa aataatgcaa ctctttatat acttgatggg
      721 aatagtgcca acaattacat ttctgatatt ctgcctgtta ttgatgcact acccaatcca
      781 ccagtgttag ttacacttgg ttatgaatct tggaataacc ttagcattca tcgccgtgct
      841 tacgattata ctcctgatgg tgaaaatgct attgttgata actctaaacc agcatggatc
      901 tactttactg gtggaggaag ccagtctttc cgagaattat tactaactca gatcatgcca
      961 tgggttagta ctattgctcc gaacagttcc agaatcggta tatgggggca ctcgctaggt
     1021 gctatttttg tgcttgattg cttaaaaaat aattcatgct ttaactatta ttatatatct
     1081 gcaccatcac ttctatggca gaatgaaaga atcatcaaga taattaaaga tgatatatca
     1141 gaatcaaagc acactaaaag tatatgcttg cttaacggaa atcttagcct tgattactcc
     1201 gcatctttat atcctgaagc catcaaagcg gaatctgttt tgagaaatat tttgacagaa
     1261 aaatacagta atttttctat tgtacaattt ccagagctca atcatcagga gactttctct
     1321 gctgcactct ggaatagcat tattcatttc agcatataac agaaaatatg taatcacttt
     1381 atcaatctag ctaacataac tgatatcaat cctaatgggt ctttgaacat attaaaagat
     1441 aacttctcat ttgtacattg ttgtgttctt agacccattt caaaaatact attttttaga
     1501 tactaataat tacatccatt tagctatctt ctaaatactc ctctcagttt cttcattgga
     1561 gctgattcaa ctccggcaat gcatactagg atcattttat aagcatacaa acaacatcca
     1621 gactgtgaat tattgctatt cattttctat gtatctgctc ttttcccatc cactgaaaca
     1681 ccagaatcca aaggtttcat gttattttca ctattccatc attactcctg tgtaaaatat
     1741 caaaactcgc tgcatcactt cactgttacg gcactcacta caaattatgt tcaattgcct
     1801 gtcatagcgg cgtatttctc cgtctggtaa tgaccagata aggtcaggat caaccacaac
     1861 cggtttcttc agttttgccc tcgatagttt tttgcgggcg ttttgccagt ccttacgagc
     1921 ctgttcagat gggaataacc cgtaaccaga gttgtataca tcgccactgg caaccagctc
     1981 tctggcaaga acgctcatca gatatcttgt cgcacctgtc ttggcttcca gttgccgtaa
     2041 cgtctcgcgc ccactccggc gtactagctc aacaacctgc cctttaattt tttcccgctc
     2101 ttcctgtgta aatacttttg ccataagcgc ctccggcaat cacttttccg atacaacacg
     2161 gcgggaagaa tcagtaatct gtcgaacaat atcccggtgc ttgttcagct cccgcagcgc
     2221 ggcgcagact cgctcccact tctgaacatc actttt
//
LOCUS       DAZUDJ010000229         2197 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.234, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000229 DAZUDJ010000000
VERSION     DAZUDJ010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2197
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.234"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..551)
                     /locus_tag="ACHY1N_005279"
     CDS             complement(<1..551)
                     /locus_tag="ACHY1N_005279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044384 - host outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HFS4047384.1"
                     /translation="MRKLYAAILSAAICLAVSVAPAWASEQQATLSAGYLHARTNAPG
                     SDNLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVAIDIAYEGSGSG"
     gene            complement(618..>2197)
                     /locus_tag="ACHY1N_005280"
     CDS             complement(618..>2197)
                     /locus_tag="ACHY1N_005280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1983 domain-containing protein"
                     /protein_id="HFS4047385.1"
                     /translation="YQVLARWDTPKVVKGVSFMLRLTVAADDGSERLVSTARTTETTY
                     RFTQLAPGNYRLTVRAANAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLA
                     VYDPTVQFEFWFSEKRITDIRQVETTARYLGTGMYWIAASINIKPGSDYYFYIRSVNT
                     VGKSAFVEAVGRASDDAEGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSIT
                     DVSNEITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGA
                     GIENTPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKYLTAPTITS
                     GGNPPAFSLTPDGKLTAKNADISGSVNANSGTLNNVTINENCRVLGKLSANQIEGDLV
                     KTVGKAFPRDSRAPERWPSGTITVRIYDDQPFDRQIVIPAVAFSGAKHEREHTDIYSS
                     CRLIVRKNGAEIYNRTALDNTLIYSGVIDMPAGHGHMTLEFSVSAWLVNNWYPTASIS
                     DLLVVVMKKATAGISIS"
BASE COUNT          480 a          649 c          537 g          531 t
ORIGIN      
        1 ccactgccgg agccttcata agcaatatca atggccacgg attcggtcgg gttaaactgc
       61 acgccagccc cccacgccag agaggtgttg ctgtggcgac cgtcatcact tccggtcagc
      121 acgtcgtgcg ttttcccctt gttgtcagtt acgcggagat aatccccgga gaaagtcgac
      181 acacggctgt aagccacacc cgccatcgca tacgcgctga accattcatt cacgcgcaca
      241 gatggccccg ccattacgct gaaccagcgg ttacgcacgg aatcttcatg ccagcgggta
      301 tcgctgtaac gggtaagctg gcgattcttg tctcctgcat agctgaatga cgtcaccagc
      361 cccagcgtgt ccgtgaattc ataacggtat ttcacgttaa tcccgttaag attatcgcta
      421 ccgggagcgt tcgtccgggc atgaagatac cccgcgctca gcgtggcctg ctgctcagac
      481 gcccatgcag gcgcgacgga tacggccaga cagatggctg cggacaaaat ggcggcataa
      541 agtttacgca taattacctc tcgcttttct gcaataaaaa aggcgtcatt tctgacgccc
      601 gttctgggtt ataaaattca gctgatactg atacctgctg tggctttctt catcaccaca
      661 accagcaaat cgctgatact tgctgtggga taccagttat tcaccagcca tgctgatacc
      721 gaaaactcca gcgtcatgtg accgtgaccg gcaggcatat caataacgcc actgtaaatc
      781 agcgtattat ccagcgcggt acggttataa atttcagcac cgtttttccg cactatcaga
      841 cggcatgagg agtaaatatc agtatgctct ctctcatgtt tagcgccgct gaatgccacc
      901 gccggaataa caatctgccg gtcaaacggc tgatcgtcat aaatcctgac ggtaatggtc
      961 cctgatggcc accgttccgg tgcacgggag tcccggggga aagctttgcc cactgtttta
     1021 acgagatcgc cttcaatctg gttcgcggac agttttccca gaacccggca gttctcgtta
     1081 atcgtgacgt tgttgagcgt cccggagttc gcattcacac tgccactgat atccgcattt
     1141 ttagcggtca gctttccgtc cggtgtcagg gaaaatgccg gaggattgcc gccactggta
     1201 atggtgggag ccgtcagata tttcaggaac acttcattca tgaatatctg atcaccctga
     1261 ccaacaaaca tcggctttgt gttgccattt gcaggattaa tcatcgcaat cctgtctgcc
     1321 gccagcagca cctgactctg catgccgtcg ggggtgttct caataccggc cccgataccc
     1381 gcaatataaa ggcgtccgtc ctgcatctgt tgcagcttca ctgcccacat gctgttcagg
     1441 ttattatttg tatcaacctg aaccttctgt atctgctgaa ttgccgcact ctggtcttcc
     1501 agtttcttat tgacggtctg tgtgatttca ttgctgacat ccgtaatgga cgtcctgatt
     1561 tcagccaggt caggcgcaag ctgaccgtta tcaatctgcg tccacaactc ctgagccaga
     1621 tgggttttcc ctatctcgcc tttgaaaaaa tccaggtaac cttccgcatc atcgctcgcc
     1681 cgaccgacgg cctccacgaa tgccgatttg ccaacggtgt tcacactgcg gatataaaag
     1741 tagtaatcag aacccggctt aatattgata ctggcggcta tccagtacat ccccgtgcca
     1801 aggtagcggg ctgtggtttc aacctgcctg atatcggtaa tccgcttttc cgagaaccag
     1861 aactcaaact gtaccgtcgg atcataaacg gcaagatgcg gcgttgcggt tatctgaaaa
     1921 tagcccggcg tcagctcaat ccgcgacggt gctgccggtg cggcaatccg gaacgatacc
     1981 gacgccggat cgccctgctg cccccaggca tttgccgccc ggactgtcag cctgtagttc
     2041 cccggcgcca gttgcgtgaa gcggtatgtg gtttccgtcg tccgggccgt gctgaccagc
     2101 cgctcactgc cgtcatccgc tgccacggtc aggcgaagca taaagctcac gcccttcacc
     2161 accttcggcg tgtcccagcg cgccagcacc tgatatt
//
LOCUS       DAZUDJ010000230         2181 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.235, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000230 DAZUDJ010000000
VERSION     DAZUDJ010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2181
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.235"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>2181
                     /locus_tag="ACHY1N_005281"
     CDS             <1..>2181
                     /locus_tag="ACHY1N_005281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HFS4047386.1"
                     /translation="AIEAGDERRARAKFHWQFLEHYPAAQDCAYKFIICEDKPGIPRP
                     ALDSWDAEYMQENRWDEESASFVPVETESDPMNVTFDKLAPEVQNAVMVKFDTCENIT
                     VDMVISAQELLQEDMATFDGHIVEALMKMPEVNAMYPELKLHAIGWVKHKCKPGAKWP
                     EIQAEMRIWKKRREGERKETGKYTSVVDLARARTNQQHTENSTGKISPVIAAIHREYK
                     QTWKTLDDELAYALWPGDVDAGNIDGSIHRWAKNEVIDNDREDWKRISASMRKQPDAL
                     RYDRQTIFGLVRERPIDIHKDPVALNKYITEYLTTKGVFEDEGTNQSATDTLSSPVPE
                     TDAVETAIPDNEKTECKVEVEPSVEREGPFYFLFTDKDGEKYGRANKLSGLDKALAAG
                     ATEITKEEYFARKNSTYSGSQQNTGASDTTAQPEPVKVTADEVNKIMQAANISQPDAD
                     KLLAASRGEFVAGISDPNDPKWVKGIQTRDSVNQNQHESERNYQKAEQNSPNALQNEP
                     ETKQPEPVAQQEVEKVCTACGQTGGGNCPDCGAVMGDATYQETFDEEYQVEVQEDDPE
                     KMEGAEHPHKENTGGNQHHDSDNETGETADHSIKVNGHQEITSTSRTCDHLMIDLETM
                     GKNPDAPIISIGAIFFDPQTGDMGPEFSKTIDLETAGGVIDRDTIKWWLKQSREAQSA
                     IMTDEIPLDDALLQLREFIDENSGEFFVQVWGNGANFDNTILRRS"
BASE COUNT          672 a          521 c          546 g          442 t
ORIGIN      
        1 gctattgaag ctggcgacga acgccgtgct cgagcaaaat ttcactggca attcctggaa
       61 cattatccgg ctgctcagga ctgcgcttat aaatttatta tctgcgagga taaacctggc
      121 ataccccgcc ctgccctcga ttcatgggat gctgaatata tgcaggaaaa ccgctgggat
      181 gaggagtctg cttcctttgt tccggttgag actgaatcag atccgatgaa cgtcactttt
      241 gacaagctgg cccctgaagt acagaacgct gtcatggtta agttcgacac atgtgaaaac
      301 atcaccgttg atatggttat tagcgcacag gaattgttgc aggaagacat ggcaacattc
      361 gacggacata tcgttgaagc gttgatgaaa atgccagaag ttaacgccat gtatccggag
      421 cttaagctgc atgccatcgg gtgggttaag cataaatgta agcctggtgc caaatggccc
      481 gaaattcagg cagagatgcg catctggaaa aaacgtcgcg aaggtgaacg caaggaaacc
      541 ggaaaataca cgtctgttgt tgatctcgcc cgcgccagaa ccaatcaaca gcacactgaa
      601 aattcaacag gaaaaatcag cccggtcatt gctgccattc atcgcgaata caagcagaca
      661 tggaaaacac tggatgacga actggcctac gctctctggc ctggtgatgt ggatgccgga
      721 aacattgacg gcagcatcca tcgctgggca aaaaatgaag ttatcgacaa cgaccgcgaa
      781 gactggaagc gtatctcggc atcaatgcgc aaacagcctg atgcccttcg ctacgaccgc
      841 cagactattt ttggccttgt ccgtgaacgt ccgatcgaca ttcacaaaga ccctgtggca
      901 ctgaacaaat acattactga atacctgact acaaagggcg tgtttgaaga tgaaggaaca
      961 aatcagagcg caactgatac tctctcgtcg ccagtaccag aaactgatgc agtggaaacg
     1021 gcaattccgg acaacgaaaa aaccgaatgc aaagtggaag tcgaaccatc tgtagagcgt
     1081 gaggggccgt tctacttcct cttcaccgac aaggatggcg aaaaatacgg tcgcgcaaac
     1141 aaactttctg gtctggataa ggcactggct gccggggcta ctgaaatcac gaaagaagaa
     1201 tatttcgccc gcaaaaacag tacatactca ggttcacaac aaaatactgg tgcatctgac
     1261 acgaccgcac aaccagagcc ggtaaaagtt accgctgacg aagtaaacaa aattatgcag
     1321 gcagccaata tcagccagcc tgacgccgat aagttgcttg ctgcctctcg cggagaattt
     1381 gttgcaggga ttagcgaccc gaatgatccg aaatgggtta aggggatcca gacccgcgat
     1441 tctgtaaacc agaaccagca tgaatcggaa cggaactacc aaaaagcgga acaaaacagc
     1501 ccaaatgcgt tacaaaacga gccagaaacg aaacagcctg aaccagtggc gcaacaggaa
     1561 gtggaaaaag tctgcaccgc ctgcggtcag accggcggcg gcaactgccc tgattgtggc
     1621 gcagtgatgg gcgacgcaac ataccaggaa acattcgatg aagagtatca ggttgaagtt
     1681 caggaagatg atccggagaa aatggaaggc gctgaacatc cacacaagga gaacactggc
     1741 ggcaatcagc atcacgatag cgataatgaa actggcgaga cggcagatca ctcaattaag
     1801 gtgaacggtc atcaagaaat cacatccacc agcaggacgt gtgaccatct aatgatcgac
     1861 cttgaaacca tgggaaaaaa tcctgatgcc ccgatcatct caataggtgc aatatttttc
     1921 gatccgcaaa ccggagatat gggaccggaa tttagtaaga ctatcgatct ggaaactgct
     1981 ggcggagtca ttgatcggga caccattaaa tggtggctta agcaatcacg cgaagcgcaa
     2041 tctgccatta tgaccgatga aatcccgtta gatgatgcac tgttacaatt gcgggaattt
     2101 atcgacgaaa actccggtga attttttgtt caggtctggg gaaatggagc caacttcgac
     2161 aacacgattt tgcgccgttc a
//
LOCUS       DAZUDJ010000231         2173 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.236, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000231 DAZUDJ010000000
VERSION     DAZUDJ010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2173
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.236"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..1493
                     /locus_tag="ACHY1N_005282"
                     /pseudo
     CDS             1..1493
                     /locus_tag="ACHY1N_005282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708765.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
     gene            1614..>2173
                     /locus_tag="ACHY1N_005283"
     CDS             1614..>2173
                     /locus_tag="ACHY1N_005283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047387.1"
                     /translation="MLQIVGALILLIAGFAILRLLFRALISTASALAGLILLCLFGPA
                     LLAGYITERITRLFHIRWLAGVFLTIAGMIISFMWGLDGKHIALEAHTFDSVKFILTT
                     ALAGGLLAVPLQIKNIQQNGITPEDISKEINGYYCCFYTAFFLMACSACAPLIALQYD
                     ISPSLMWWGGLLYWLAALVTQLWAAS"
BASE COUNT          474 a          597 c          625 g          477 t
ORIGIN      
        1 aagctgaccg gcagcactgt gctgaacggt gccattgacc ccacgaatgt cactctcgcc
       61 tctggtgcca cctggaatat tcccgataac gccacggtgc agtcggtggt ggatgacctc
      121 agccatgccg gacagattca tttcacctcc acccgcacag ggaagttcgt accggcaacc
      181 ctgaaagtga aaaacctgaa cggacagaat ggcaccatca gcctgcgtgt acgcccggat
      241 atggcacaga acaatgctga cagactggtc attgacggtg gcagggcaac cggaaaaacc
      301 atcctgaacc tggtgaacgc cggcaacagt gcgtcggggc tggcgaccag cggtaagggt
      361 attcaggtgg tggaagccat taacggtgcc accacggagg aaggggcctt tgtccagggg
      421 aataagctgc aggccggtgc ctttaactac tccctcaacc gggacagtga tgagagctgg
      481 tatctgcgca gtgaaaatgc ttatcgtgca gaagtccccc tgtatgcctc catgctgaca
      541 caggcaatgg actatgaccg gattctggca ggctcccgca gccatcagac cggtgtaaac
      601 ggtgaaaata acagcgtccg tctcagcatt cagggcggtc atctcggtca cgataacaac
      661 ggcggtattg cccgtggagc cacgccggaa agcagcggca gctatggctt cgtccgtctg
      721 gagggtgacc tgctcagaac agaggttgcc ggtatgtctg tgaccgcggg ggtatatggt
      781 gctgctggcc attcttccgt tgatgttaag gatgatgacg gctcccgtgc cggcacggtc
      841 cgggatgatg ccggcagcct gggcggatac ctgaatctga tacacaacgc ctccggcctg
      901 tgggctgaca ttgtggccca gggaacccgc cacagcatga aagcctcatc ggacaataac
      961 gacttccgcg cccggggctg gggctggctg ggttcgctgg aaaccggtct gcccttcagt
     1021 atcactgaca atctgatgct ggagccgcaa ctgcagtaca cctggcaggg actctccctg
     1081 gatgacggcc aggataacgc cggttatgtg aagttcgggc atggcagtgc acaacatgtg
     1141 cgtgccggct tccgtctggg cagccacaac gatatgaact ttggtaaagg cacctcatcc
     1201 cgtgacaccc tgcgcggcag tgccaaacac agtgtgcgtg aactgccggt gaactggtgg
     1261 gtacagcctt ctgttatccg caccttcagc tcccgggggg acatgagcat gggtacagcc
     1321 gcagccggca gtaacatgac gttctcaccg tcacagaatg gtacgtcact ggactggaag
     1381 cccgtgtccg ggaaaatatc accctgggcg ttcaggcagg ttatgtccac agcgtcagcg
     1441 gcagcagcgc tgaaggctat aacggtcagg ccacgctgaa tgtgaccttc tgacagaacc
     1501 atcgcctctc tgtggtcccg gtcatcatga tcgggacccg gaccggcgca acggatattc
     1561 aacgccacat tcgctggcat taacaataac atgatattca tcacggagtg actatgttac
     1621 agatagtcgg cgcgctgatc ctgctgatcg caggatttgc cattcttcgc cttttgttca
     1681 gagcattaat cagcacggct tctgcgctgg cagggctcat attgctgtgt ctgttcggcc
     1741 cggccttact ggctggctat atcaccgaac gcataacccg gttgttccat attcgctggc
     1801 tggcaggcgt atttctgacg attgccggaa tgatcatcag cttcatgtgg ggacttgatg
     1861 gtaaacatat cgcgctggag gctcacacct ttgactctgt gaaatttatt ctgaccactg
     1921 ctctcgccgg tggtctgctg gctgttcccc tgcagatcaa aaacattcag cagaacggga
     1981 tcacaccaga agatatcagc aaggaaatta acgggtatta ctgctgtttt tatactgcct
     2041 ttttccttat ggcgtgttct gcatgcgcac cattgatcgc gttacagtac gatatttcac
     2101 cgtcactgat gtggtggggc gggttgttgt actggctggc tgcattagtg acgcagctat
     2161 gggcggccag cca
//
LOCUS       DAZUDJ010000232         2171 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.237, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000232 DAZUDJ010000000
VERSION     DAZUDJ010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2171
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.237"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            30..602
                     /locus_tag="ACHY1N_005284"
     CDS             30..602
                     /locus_tag="ACHY1N_005284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1076 domain-containing protein"
                     /protein_id="HFS4047388.1"
                     /translation="MPGLISYVSSASFVNEMMELRQQVMEGQIGGFLLGGERVRVSYM
                     PDTGRFLAESEGRGRVYAELLNIAFNDGVNVLRNRILSALPGMGGRNSLQEKISECAF
                     TVDIEKLQCPGDALQCPITLEQPENGVFIKNSGNSAVCTLFDSVSFSHLVREGGVHPL
                     TRETITPSMIVKPEDCIFDSSKGNFIIKDG"
     gene            820..1518
                     /gene="nleD"
                     /locus_tag="ACHY1N_005285"
     CDS             820..1518
                     /gene="nleD"
                     /locus_tag="ACHY1N_005285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector zinc metalloprotease NleD"
                     /protein_id="HFS4047389.1"
                     /translation="MRPTSLNLALHQSSTSSSMSDADIESLVKTSSVQWIKNNPQLRF
                     QGTDHNIYQQIEAALDKIGSTETGRVLLNAIESISRLKSETVVIHLNSSRLGVIAHRD
                     IDAENHRGTGSDFHCNLNAVEYPCGEGISVVDFHATIVFHELLHVFHNLNGERLKVES
                     SRPESQKYSPLLLEEARTVGLGAFSEEVLSENKFREEIGMPRRTSYPHDSALIHDDNT
                     VSQGFLQVRLHPLL"
BASE COUNT          633 a          406 c          519 g          613 t
ORIGIN      
        1 aatatttatc cgtatgaagg aatatggtaa tgcctggatt aatatcatat gtgtcatcgg
       61 cttcattcgt gaatgagatg atggagctgc gtcagcaggt aatggagggg cagattggtg
      121 gatttctcct gggaggggag agggttagag tttcttatat gccagataca ggccgttttt
      181 tagcagaaag tgaagggcgg ggacgggttt atgcagaatt attgaatatt gcttttaatg
      241 atggagttaa tgtgctcaga aacaggatat taagtgcgct ccctggaatg ggagggcgaa
      301 actctttgca ggaaaaaata tcggagtgtg cctttactgt cgatattgaa aaacttcaat
      361 gtcctggtga tgcgcttcaa tgtccaatta cactggagca gcctgaaaat ggtgttttca
      421 ttaagaattc aggaaattct gcggtttgca ccctgtttga ttcggtttct ttttctcatt
      481 tggtccgtga aggtggggtt cacccactga cacgagagac aataactcca tcaatgattg
      541 taaagccaga agattgtata tttgacagtt caaagggaaa cttcattata aaagatggtt
      601 aaaatgtttt acatgaagca atattgattt tcggtagttt gtataaaaca ccacagacat
      661 tcaaaatgtc agaggatgtc agtggtggat gtacctggag cggaagttgt ggaagtaagt
      721 tatgttatat cgcaataaac cgaatacatc tgtgatgtta cattggtctg agcttcagtg
      781 tgtggtgaat gaaactcgta acattttcag aggtccttga tgcgccctac gtccctcaac
      841 ttggcattac atcagtcatc aacgtcgagt tcaatgtcag atgcagatat cgagtctctt
      901 gtaaaaacat cgagcgttca atggataaaa aacaatccgc aacttcgttt ccaggggact
      961 gatcataata tatatcaaca gattgaagca gcgctcgata agattggctc tacagagaca
     1021 gggcgtgtac tcctgaatgc tattgaatca atatcccgac ttaaatcaga aacagtggta
     1081 atacacctca attcttccag actaggagtt attgcacata gagatataga tgctgagaac
     1141 catcggggaa ctggttccga ttttcactgt aatctgaatg cagttgaata tccctgtggg
     1201 gaggggatta gcgtggtgga ctttcatgcg actattgttt ttcatgagct gctccatgtg
     1261 ttccacaatt taaatgggga gcgcctgaaa gttgagagtt cccgaccaga atcacaaaaa
     1321 tactctccac ttttactcga agaagccaga actgttgggt tgggggcttt ttcagaggag
     1381 gtgctttcag aaaataaatt ccgcgaagag attgggatgc cccgtagaac atcctaccct
     1441 cacgactcag ctctcattca tgatgacaat acagtgagtc agggattcct acaggtaaga
     1501 ctgcatccat tgctttaggt gtgtttcttg tggtgaatat atattggtgg gataaaactg
     1561 agatacataa ggtctcacaa tggcttgcaa ggctttgtgc ttctctgtag aggcgacatg
     1621 tttttatccg gtgcgccgta aaaccccgtc cttcagggcg tggaggatgt caaataataa
     1681 ggaatagtgg atatgtttgc agcaaagccc gagagcagtc aaagaagtat ttctggatta
     1741 ttcagtccta ggtcaaatgg tgaaaacgca agtaataaac cgtcaagtgg tatggcgaac
     1801 agaatcaaac cagttgtaag cgattcacaa atcggtagat atacaactga cagtaatact
     1861 ctgaaggatg gattgtgtag ccaagcccac ataggaactc aaccttatcg gccaggtgct
     1921 gactcgccgc taactgtgag atcattccta caaattacac tttccaacaa taattacaaa
     1981 tcatgagtct gccctgtccc ttctgccagg aagtgttacg caacgatatc tcaccaatct
     2041 ttcgcaccac tattaatcaa tgagttagag gtgattagtg acctgagaca gagcattagc
     2101 gcaaggtgat tttttgtccg taagcgtaaa ccgatcgccg tatgtagcca ttagacaaga
     2161 attggtaact t
//
LOCUS       DAZUDJ010000233         2166 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.238, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000233 DAZUDJ010000000
VERSION     DAZUDJ010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2166
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.238"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..341)
                     /locus_tag="ACHY1N_005286"
     CDS             complement(<1..341)
                     /locus_tag="ACHY1N_005286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HFS4047390.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     AITSANIDRLR"
     gene            complement(402..1049)
                     /locus_tag="ACHY1N_005287"
     CDS             complement(402..1049)
                     /locus_tag="ACHY1N_005287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HFS4047391.1"
                     /translation="MAATHTLPLASPGMARICLYGDLQRFGRRIDLRVKTGAEAIRAL
                     ATQLPVFRQKLNEGWYQVRIAGRDAGENELSARLNEPLANGAVIHIVPRLAGAKSGGV
                     FQVVLGAALIAVAWWNPVGWLGAAAVSGMYAAGASMILGGVAQMLAPKARTPTAASTD
                     NGKQNTYFSSLDNMVAQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            complement(947..1690)
                     /locus_tag="ACHY1N_005288"
     CDS             complement(947..1690)
                     /locus_tag="ACHY1N_005288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFS4047392.1"
                     /translation="MTETESAILAHARRCAPAESCGFVVRTPEGERYFPCVNISGEPE
                     AYFRMSPEDWLSAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGAIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHRGDDWWRHGQNLYLDNMEAT
                     GLYQVPLSAAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWHASAFTGICNDLVAVSTFV"
     gene            complement(1696..>2166)
                     /locus_tag="ACHY1N_005289"
     CDS             complement(1696..>2166)
                     /locus_tag="ACHY1N_005289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030430 - host cell cytoplasm [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HFS4047393.1"
                     /translation="PTLTVSNLYGMVTGMAEDMQSLVGGTVVRRKVYARFLDAVNFVN
                     GNSYADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDGAVFPGRIMLANTCTWTYR
                     GDECGYHGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNVGNFGGFLSINKLSQ"
BASE COUNT          457 a          727 c          541 g          441 t
ORIGIN      
        1 aagcgcagtc ggtcgatgtt tgccgacgtg atggcgcggg tgatcggcgt gtcatatttc
       61 acttctgtac cgagcaccgt ctcggagccg gaggattcaa atccctccgg cggtgtctgc
      121 tcctgctcac cggcccggaa caccaccgtg acgccggata tattggtatt cccctcactg
      181 tccagcaccg gcgtactgtt cagcagcacg ctttttaatc catccaccgg accttcaacc
      241 ggcccttcgc tgatggcatc gatcacactc agcagctgcg tggacttcag gttgtccttc
      301 gcttcgcgcg gggtatgccc cttactgctg cctttaccca ttcctcacgc tccataaacg
      361 ataaaaccgc ccggaggcgg tttcacataa aacattttgc atcagcgacc aatcaccaca
      421 acctgaccac catccccttc gtctgccgtg ctgatctcct gagaaaccac acgtgacccc
      481 acgcgcattt caccgtacag aacaggcaga acattgccct gggcaaccat gttatccagt
      541 gaggagaaat aggtgttctg tttgccgtta tctgtactgg ctgccgtggg cgtcctggct
      601 ttcggtgcca gcatctgcgc cactccgccc aggatcatac tggcccctgc cgcatacatg
      661 cccgatacag ccgcggcccc cagccagccc acagggttcc accatgccac cgcaatcagc
      721 gccgccccaa gcaccacctg aaacacaccg ccacttttag ctcccgccag acgcggcacg
      781 atgtggatca cggcaccatt tgccagcggc tcattaagac gggcagataa ttcattttcg
      841 cctgcatcac gcccggcaat gcgcacctga taccagccct cattcagttt ctgacgaaac
      901 accgggagct gtgtggccag tgcccggatg gcttcagccc ccgttttcac acgaaggtcg
      961 atacggcgac caaatcgttg caaatccccg taaaggcaga tgcgtgccat gcccggtgac
     1021 gccagaggga gtgtgtgcgt cgctgccatt tgtcggtgta cctctctcgt ttactcagtt
     1081 gttcaggaat atggtgcagc agctcgccgt cgccacagta aatggcggca tgattcggca
     1141 ccgatgaacc aaaacagcac agcagcacat cgcccggctg ggccgctgac aacggcacct
     1201 gatacaaccc cgttgcctcc atattatcca gatagagatt ctggccgtga cgccaccagt
     1261 catccccgcg atgaaaatcc ggcatctcaa ttcccgccag atggtaagcg tcccggaaca
     1321 gcgtgtaaca gtccgtcacc ccgtgctcaa agcgccgccc ggtgagatgc ggcacacagc
     1381 ggaatttatg aatcgccccc cggcagacca gccaccacgg caaatcactc tgcacctgca
     1441 gccgccggtc ggcctcactc agccagggca gaccaccggg gtggctgtgg accagcgcca
     1501 caatctctcc ctgcatttct gcactcagcc agtcctccgg cgacatccgg aaatacgcct
     1561 ccggctcacc agagatattc acgcagggaa aatatctttc cccctccggt gttctcacca
     1621 cgaagccgca cgactccgct ggcgcacatc gccgggcgtg cgccagaatc gctgattctg
     1681 tctctgtcat gggattcact gcgaaagttt gttaatggaa aggaagccgc caaagttgcc
     1741 gacgttattg cgaaacttac agccgctcag gcatttgctg catttatcct tcgtgatatc
     1801 ggacgtcggc tgatcatatt catccgcgac cgccggaccg tgataaccgc actcgtcacc
     1861 gcgataggtc caggtgcagg tgttggccag catgatgcgc cccggaaaaa cggcaccgtc
     1921 cgtttccgtc ggcgtggaca gtacaaaaga ggcactcacc gcgctcagtt cgctgcactg
     1981 ctcgatgcgc cagcggctga tcacctcctg ctccggatcg gcgtaactgt ttccgttgac
     2041 gaagttcacc gcatccagaa aacgggcgta aaccttacgc cggaccaccg ttccgccgac
     2101 cagactctgc atatcttccg ccatcccggt gaccataccg tacaggttag aaaccgtcag
     2161 cgtggg
//
LOCUS       DAZUDJ010000234         2160 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.239, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000234 DAZUDJ010000000
VERSION     DAZUDJ010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2160
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.239"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            418..582
                     /locus_tag="ACHY1N_005290"
                     /pseudo
     CDS             418..582
                     /locus_tag="ACHY1N_005290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366616.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
     gene            625..1821
                     /locus_tag="ACHY1N_005291"
                     /pseudo
     CDS             625..1821
                     /locus_tag="ACHY1N_005291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611482.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1904..>2160
                     /locus_tag="ACHY1N_005292"
     CDS             1904..>2160
                     /locus_tag="ACHY1N_005292"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HFS4047394.1"
                     /translation="MTLVNDTGFDPVFSGSIAESWRQQPCTPSYCCDWEAAAMLRAFP
                     LAKKGEGRARLPSLYASFGKLGETPTHEDIINNNRSINWPV"
BASE COUNT          615 a          498 c          566 g          481 t
ORIGIN      
        1 gtcatcggcg gcgcatacga acgatcgtgg tctgacgatg gttgatttat tttgttgcac
       61 aagggcaaca gcttagctgg tacccgaggc tggctatgaa gtgctgagtc gggtaattgc
      121 gtcatagtgg gctcaaacgt ttgacgatga tgctgaccag aagctattct ggaccagatc
      181 ttacacctct caggcctcgt taaaataaag gaggaatgaa tcgaaccaga cagaaatgaa
      241 aggccggagt tatagcagag gctaatcctg agtaaaacag tgcatcaata ctaggacgtt
      301 agtggagcac ttttcatctg acattgacag caatgtatat tatatcggtt atccgtggca
      361 atttagacca cataacaatt caagagtaag taatgttaca gtagaggaaa agtcacgatg
      421 actcttttgg atagtgtcga agcaggcaag ctgactctca gagaattaat tgatactctt
      481 gcaaaagata aaaattacaa agcttccaag tgggatcagc gataccgtga atttacgacc
      541 ttgctacaac aaaccttaac ttttgctgag cctgaaacgg atgtgtagtg gtttactgaa
      601 tttggccacc tgaacagagg tgagatgctc acctcagaac aacacaggtg ctccaatgaa
      661 aaaagaaatt tcagcgcaga gtttaaacgc gaatccgctc aactggttgt tgaccagaac
      721 tacacggtgg cagatgccgc caaagctatg gatgttggcc tttccacaat gacaagatgg
      781 gtcaaacaac tgcgtgatga gcgtcagggc aaaacaccaa aaacctctcc gataacacca
      841 gaacaaatcg aaatacgtga gctgaggaaa aagctacaac gcattgaaat ggagaatgaa
      901 atattaaaaa ggctaccgcg ctcttgatgt cagactccct gaacagttct cgataatcgg
      961 gaaactcaga gtgcattatc ctgtggtcac actctgccat gtgttcgggg ttcatcgcag
     1021 cagctacaga tactggaaaa accgtcctga aaaaccagac ggcagacggg ctgtattacg
     1081 cagtcaggta cttaagctac atggcatcag ccacggttcg gtcggagcaa gaagcatcgc
     1141 cacaatggca acccggagag gctaccagat gggatgctgg cttgttggca ggctcatgaa
     1201 agagctgggg ctggtcagct gtcagcagcc gactcaccgg tataaacgtg gtggtcatga
     1261 acatgttgct atccctaact accttgaacg gcagttcgcc gtgaccgagc caaatcaggt
     1321 gtagtgcggt gatgtgacct atatctggac gggtaagcgc cgggcgtacc tcgtcgttgt
     1381 tctcgacctg ttcgcaagaa aaccagtggg ctgggccatg tcgttctcgc cggacagcag
     1441 gcttaccatg aaagcactgg aaatggcatg ggaaacccgt ggtaagcccg tcggggtgat
     1501 gttccaagcg atcaaggcag tcattatacg agcaggcagt tccggcagtt actgtggcga
     1561 taccggatca ggcagagtat gagtcggcgt ggaaactgct gggataacag cccaatggag
     1621 cgcttcttca ggagtctgaa gaacgaatgg gtaccagcga cgggctatgt aagcttcagc
     1681 gatgcagctc acgcaataac ggactatatc gttggatatt acagcgcact aagaccgcac
     1741 gaatataatg gtgggttacc accaaacgaa tcagaaaacc gatactggaa aaactctaac
     1801 gcggaggcca gttttagttg accacaacag actacctgaa gggagccgcg gtcgcctagc
     1861 agttgcagta gcaggagatc atccagccgc agtacaggtc acgatgactc tggttaatga
     1921 taccggcttt gaccccgtat tttcaggctc tatcgctgaa tcatggcgtc agcagccgtg
     1981 cacaccatcc tattgttgtg actgggaggc tgccgccatg cttcgcgctt tccctctggc
     2041 gaaaaaggga gaaggacggg cccgtctgcc ttcactttat gccagcttcg gtaagctggg
     2101 tgagacaccg actcatgaag atatcattaa taacaatcga tccatcaact ggcctgtata
//
LOCUS       DAZUDJ010000235         2156 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.240, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000235 DAZUDJ010000000
VERSION     DAZUDJ010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2156
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.240"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(1..1784)
                     /locus_tag="ACHY1N_005293"
                     /pseudo
     CDS             complement(1..1784)
                     /locus_tag="ACHY1N_005293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309571.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            complement(1730..1951)
                     /locus_tag="ACHY1N_005294"
     CDS             complement(1730..1951)
                     /locus_tag="ACHY1N_005294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047395.1"
                     /translation="MAKIRYLQGTHDARAGDIRDVAQPCAEVLVRLGKAEYITVRRPA
                     GQKKKRDAEHGECGTFYGEPEKTRNQDVT"
     gene            complement(1996..>2156)
                     /locus_tag="ACHY1N_005295"
     CDS             complement(1996..>2156)
                     /locus_tag="ACHY1N_005295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047396.1"
                     /translation="GDSTTPSPVELVSMFQTGSVAIRAERWINWRRRRTAAVAVITGV
                     NYGSASGG"
BASE COUNT          429 a          701 c          535 g          491 t
ORIGIN      
        1 cagtacttcc ggatcataat cacgaccgtc acgcggagca gggatatggc ttacagcctc
       61 tttcaccatc tgctcaagca tcggacgcac atcatcgggg gtgatacttt tgccgtccgc
      121 cggtaccgga atattcgcaa ccgcatcatt caccgcctgc tgcagtacat ccggatcata
      181 atcacgacca tcacgcggta ccggaatggt ccccacagcg tcatccacca tcgcctgcag
      241 aaccggatgt acctcatcca ccgtcacatg cttctgtaat accgccgaca gggaagccag
      301 tttctcttca aacgcttgtg cctgcgcggc catcttcccc tcaaatgtgc gctgtaaatc
      361 cgccagcacc gtggagaatt cttcgcccag tgcacgaata atggacagtt cccgttccgt
      421 cattttctca gtatccccct gaacatcgct ttcactgcat catgctctgt ttcactgatt
      481 gccttattac cgtcagatgc gccgtcaggc agttgtgctg aaactgtttt cccggccgac
      541 gcgaacgggt cctcacgggc atcacgacgg gacagcgcct ccagactgta gttctgctgc
      601 tgaagataca gtgcatcacc gccggcaagg ggcggcaggt tctcacgttt acgggcctca
      661 ttgggcgtga gaagcgtatt tttcaccgat tcacccagtg ttttcatgcg ccgttcgctg
      721 tccattctca gcagcgtggt gacgtcaaac tccgtgctct cgttttcccc cgtttccagc
      781 gcctcatcca gtaacagctc aatggactca atcagcgtct gcagacactg ggaataatac
      841 tgctgctcca gcgcctccac gttgtcactg gaaggcgggt ggccaacgcc aatcttgtag
      901 gccgggacac ggaacaccga acagacaatt tcagcggtca tcttcagttg ttccaccgtc
      961 tgcgcatcca caggtgaaaa cgtcgtgggg ttgtattttg ccccgttgct cagaatggcc
     1021 gttttccccg cattttcgcc tgtatacccg ctgtcccagt tgctcttcag ttttttcgca
     1081 ttttcttccg ttatactgcc ggggatctca atcaccccgg acggcctgcc gccatttctg
     1141 aaaaaagacg tcgaattttc ctgaatatga tgcccctgcg tggccgccag cccggcggca
     1201 tacaccggcg gcaatcctat aagcggatga aaaaaacagt taaaccggtc gtggatcact
     1261 tcccgggcag gcaccgtcac cgcctccgtg atcccgcagt tccggtccgg cgtgatgcgg
     1321 tagaacacct cgccgtcatc cgccaccaga ggttcaaccc ggctccagtc cagaatacgc
     1381 agttctttga tctgcccccg ggcattacgg attttcagca ccaccgtatt gccatgacgc
     1441 agtttggcgt tcagccacag ttcaaaaaac tggatgcggt tctgctgggc gttgggacga
     1501 cgacagaggc gggcaatatc cccccggcgc gtttccctgc gtatcccatg cgcatccgtc
     1561 tgcataagac gcagccgcat tttggcgata tcctgggata tcagcgaaat acatgcaaac
     1621 accgcatgaa aggagaggac ggcttcagga tcggctttca cgccctgctg ccaggcgccg
     1681 gaaaagggct cagccaccgc ctgaaacagg ctggtccagc ccgcctctct tacgtcacgt
     1741 cctgatttct ggttttttcg ggttcgccgt aaaaggttcc acattcgcca tgctccgcat
     1801 cacgtttctt tttctgacct gccggacgtc gcaccgtgat gtactccgcc tttcccaggc
     1861 gaaccagcac ctccgcacac ggctgtgcca catcacggat atccccggcc cgggcatcat
     1921 gcgtgccctg cagatatcgg atctttgcca taacctgtta cgggaggcgc acgcctcccg
     1981 tcctccttat cagactcagc cgccggacgc actgccgtag ttcactccgg tgatcaccgc
     2041 caccgccgca gtacggcgac gacgccagtt gatccagcgc tccgcacgga tggccacgct
     2101 gcctgtctgg aacatggaaa ccagctccac cggggacggc gtggtactgt cgccgg
//
LOCUS       DAZUDJ010000236         2089 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.241, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000236 DAZUDJ010000000
VERSION     DAZUDJ010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2089
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.241"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..899)
                     /locus_tag="ACHY1N_005296"
     CDS             complement(<1..899)
                     /locus_tag="ACHY1N_005296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HFS4047397.1"
                     /translation="MAVKISGVLKDGTGKPVENCTIQLKARRTSSTVVVNTVASENPD
                     EAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYEDSQPGTLNDFLGAMSEDDVRPEA
                     LRRFELMVEEVARHAEEAKKNAGEAETSARNAGISASQAEEGAANADTSAGEASESAR
                     QAAESAAAAKQSEEASSSSASAAAQKASESSQSAAEAELSRKTAESAAGNAARDATTA
                     TEKARESAESAQSAEQSRIAAEEAVNRIPTVVGPPGPKGEPGPAGPQGPKGDKGERGD
                     TGPAGATGERGPRGDTGPAGPQGP"
     gene            complement(964..1563)
                     /locus_tag="ACHY1N_005297"
     CDS             complement(964..1563)
                     /locus_tag="ACHY1N_005297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044384 - host outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HFS4047398.1"
                     /translation="MRKLYAAILSAAICLTVSGAPAWASEQQATLSAGYLHARTNAPG
                     SDNLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF"
     gene            complement(1631..>2089)
                     /locus_tag="ACHY1N_005298"
     CDS             complement(1631..>2089)
                     /locus_tag="ACHY1N_005298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047399.1"
                     /translation="ENCRVLGKLSANQIEGDLVKTVGKAFPRDSRAPERWPSGTITVR
                     VYDDQPFDRQIVIPAVAFSGAKHEREHTDIYSSCRLIVRKNGAEIYNRTALDNTLIYS
                     GVIDMPAGHGHMTLEFSVSAWLVNNWYPTASISDLLVVVMKKSTAGISIS"
BASE COUNT          411 a          665 c          505 g          508 t
ORIGIN      
        1 ggcccctgcg ggcctgccgg accagtatct cctctcggcc ccctttcacc ggttgcccct
       61 gccgggccgg tgtcgccacg ctctccttta tctcccttcg gcccctgagg acccgcggga
      121 cccggttccc cctttggccc gggaggcccc accacggtgg ggattcggtt tacggcctct
      181 tccgccgcta tcctgctttg ttccgctgac tgtgcgcttt ctgctgactc ccgggctttt
      241 tctgttgcgg tcgttgcatc cctggctgca ttaccggctg cactttctgc cgtctttctt
      301 gacaattcag cttctgctgc actttgtgat gactcactgg ctttttgagc ggccgcagag
      361 gccgaggacg aggacgcttc ctctgactgc tttgcagcgg ctgcactttc tgccgcctgc
      421 cgggctgact ccgatgcctc ccctgctgaa gtgtcagcat ttgcagcgcc ctcttctgcc
      481 tgactggctg atatgccggc attcctcgct gacgtctccg cctctccggc attcttcttc
      541 gcctcctctg cgtgacgcgc cacctcttcc accatcagtt caaaacggcg cagtgcctcc
      601 ggccggacgt catcctccga catggcaccg agaaaatcat tcagcgtccc cggttgagaa
      661 tcttcataca cggtgatggt cccggcatgt gacggcggga agccctccac caacagaatg
      721 acgctgtact gaccgtactc aacgtccatg ctgtaacgac cggcttcatc cggattttca
      781 gaggccaccg tattcaccac caccgtgctg ctggtccgtc tggctttcag ttgaatggtg
      841 cagttctcta ccggttttcc tgtgccgtct ttcagtacac ctgaaatctt tactgccata
      901 ttcaccccac aaaaaagccc gcctgaaccg gcgggctgtc ataacactgt gttacctggc
      961 taatcagaat ttatagccga cacccacgat gaagccgtca gtgcgccagt cgccactgcc
     1021 ggagccttca taagcaatat caatggccac ggattcggtc gggttaaact gcacgccagc
     1081 tccccacgcc agagacgtgt tgctgtggcg accgtcatca cttccggtca gcacatcgtg
     1141 cgttttcccc ttgttgtcag ttacgcgaag ataatccccg gagaaagtcg acacacggct
     1201 gtaagccaca cccgccatcg catacgcgct gaaccattca ttcacgcgca cagacggccc
     1261 cgccattacg ctgaaccagc ggttacgcac ggaatcttca tgccagcggg tatcgctgta
     1321 acgggtaagc tggcgattct tgtctcctgc atagctgaat gacgtcacca gccccagcgt
     1381 gtccgtaaac tcataacggt atttcacgtt aatcccgtta agattatcgc taccgggagc
     1441 gttcgtccgg gcatgaagat accccgcgct cagcgtggcc tgctgctcag acgcccatgc
     1501 aggcgcaccg gatacggtca gacaaatggc tgcggacaaa atggcggcat aaagtttacg
     1561 cataattacc tctcgctttt ctgcaataaa aaaaggcgtc atttctgacg cccgttctgg
     1621 gttataaaat tcagctgata ctgatacctg ctgtggattt tttcatcacc acaaccagca
     1681 gatcgctgat acttgctgtg ggataccagt tatttaccag ccatgctgac accgaaaact
     1741 ccagcgtcat gtgaccgtga ccggcaggca tatcaataac gccactgtaa atcagcgtat
     1801 tatccagcgc ggtacggtta taaatttcag caccgttttt ccgcactatc agacggcatg
     1861 aggagtaaat atcagtatgc tctctctcat gtttagcgcc gctgaatgcc accgccggaa
     1921 taacaatttg ccggtcaaac ggctgatcgt cataaaccct gacggtaatg gtccctgatg
     1981 gccaccgctc cggtgcacgg gaatcccggg ggaaagcttt gcccactgtt ttaacgagat
     2041 cgccttcaat ctggttcgcg gacagttttc ccagaacccg acagttctc
//
LOCUS       DAZUDJ010000237         2073 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.242, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000237 DAZUDJ010000000
VERSION     DAZUDJ010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2073
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.242"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..426
                     /locus_tag="ACHY1N_005299"
     CDS             <1..426
                     /locus_tag="ACHY1N_005299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HFS4047400.1"
                     /translation="NHTTAYRDGAGIWTICRGATRVDGKPVIPGMKLSKEKCDRVNAI
                     ERDKALAWVEKNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRKGACEA
                     IRWWIKDGGRDCRIRSNNCYGQVSRRDQESALACWGIDR"
     gene            697..1266
                     /locus_tag="ACHY1N_005300"
     CDS             697..1266
                     /locus_tag="ACHY1N_005300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor N-terminal domain-containing
                     protein"
                     /protein_id="HFS4047401.1"
                     /translation="MNMMAVPFHGNSLYVVNHNGEPYVPMKPVVAGMGLAWQSQLAKL
                     RQRFASTITEIVMVAEDGKQRNMVSMPLRKLAGWLQTINPNKVKPEIRDKVIRYQEEC
                     DDVLYEYWTKGFVVNPRKMSVMEELNQACADMKRDKNIASVFATGLNEWKQVKAAHVS
                     KIRTLVNEANMLIDFVLADTGKGKITKAD"
     gene            1266..1412
                     /locus_tag="ACHY1N_005301"
     CDS             1266..1412
                     /locus_tag="ACHY1N_005301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047402.1"
                     /translation="MGWLMISDKLITLVKSLCVLVGISFLVMLVAIFFSTAWRVLTLS
                     GLVG"
     gene            1640..1825
                     /locus_tag="ACHY1N_005302"
     CDS             1640..1825
                     /locus_tag="ACHY1N_005302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rz1 family lipoprotein"
                     /protein_id="HFS4047403.1"
                     /translation="MRELKMKLCVLMLPLVVSACGSTPPAPVPCVKPPAPPAWIMQPA
                     PDWQTPLNGIISSSENG"
BASE COUNT          545 a          473 c          577 g          478 t
ORIGIN      
        1 aaccacacca cagcataccg tgatggtgcg ggtatctgga ccatctgccg tggagccacc
       61 cgggtggatg gtaagcctgt tattcctggc atgaagctgt cgaaggaaaa atgcgaccgg
      121 gttaacgcca ttgagcgtga taaggcgctg gcatgggtgg agaaaaacat caaagtgccg
      181 ctgaccgaac cccagaaagc ggggatcgcg tcattctgtc cgtacaacat tggtcccggt
      241 aagtgtttcc cgtcgacgtt ttacagacga attaatgcag gtgatcgaaa aggtgcctgc
      301 gaagctattc gctggtggat taaggacggt ggcagagact gccgtattcg ttcaaacaac
      361 tgttacggtc aggtatcccg tcgtgaccag gagagcgcgc tggcgtgctg gggaatcgac
      421 agataagaag aatattttgc tgaaaaatga ggtttgctta catggacgga taacacgaaa
      481 tcctgcaaat tggcaaaatg taagtgaata aagtcaaaac agttgtttaa cactcaggca
      541 ccgtaatgat gcctttgtca tttctgcgca tctcacgcgc atctcacaac acagaacctt
      601 tcaggatgac ccttgaggat accggtttgg ctgtcggtgc ctttctgtgg gctggattcc
      661 tgtgagacaa ggttcatcac taaaaggaaa taaccgatga atatgatggc cgtgccgttt
      721 cacggcaact ctctttatgt agttaaccat aatggcgaac catacgttcc catgaaacct
      781 gtcgttgcgg ggatggggct ggcctggcaa tcacagttgg ctaagttaag acagcgtttt
      841 gcgtcaacta taacggaaat cgttatggtt gctgaggatg ggaaacaacg caatatggtg
      901 tccatgccac ttcgaaaact tgccggctgg ctacaaacca ttaatcccaa caaagtaaaa
      961 cccgaaatcc gcgataaggt catccggtat caggaagagt gcgacgatgt tctttacgag
     1021 tactggacga agggttttgt cgttaatccc cgtaaaatga gcgtgatgga agaactcaac
     1081 caggcttgtg ctgacatgaa acgggataaa aacattgcca gtgtgtttgc taccgggctg
     1141 aatgagtgga aacaggttaa agccgcgcat gtatcaaaaa tccgtacgct ggtaaatgaa
     1201 gcgaatatgc tgattgattt tgtcctggct gatacaggca aagggaaaat aacaaaggcg
     1261 gattgatggg gtggctaatg atatcagata aactcataac gctggtgaag agcctctgtg
     1321 tacttgtcgg catttcattt ttagtcatgc tggttgccat tttcttttcc accgcctggc
     1381 gagtcctgac gttatcggga ctggtggggt gaaagagaga tgaaccgtgt tctgtgtgtg
     1441 gtgattattg tcctggcggt tggctatggt gcgctgtggc tggcaacaaa ccattaccgt
     1501 gacaacgcgc tcacctacaa agcgcagcgc gataaaaaag ccagagagct ggaacaggcg
     1561 aatgccacca ttactgacat gcaggtgcgc cagcgtgatg ttgctgcgct cgatgcaaaa
     1621 tactcgaggg agttagccga tgcgagagct gaaaatgaaa ctctgcgtgc tgatgttgcc
     1681 gctggtcgta agcgcctgcg gatcaacgcc acctgctccg gtaccgtgcg tgaagccacc
     1741 ggcacctccg gcgtggataa tgcaaccggc ccccgactgg cagacaccgc tgaacgggat
     1801 tatttcatcc tcagagaacg gttgatgaca atgcagaagc agctggaagg ggcacaggac
     1861 tatatccgca ctcagtgcct gaactaagtt ttgctgatgc gccgtatcgt caccgtattc
     1921 ctgcattaac agagaccgca gccagacagg gagactcctc tgcgagagtg tgcggggata
     1981 atcaaaaacg atacacaccg gggtttaccg cgttaacgga gcgcggtgtt gtcccctcat
     2041 agtcgccagt ccggtgcgat ggtggaagaa act
//
LOCUS       DAZUDJ010000238         2062 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.243, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000238 DAZUDJ010000000
VERSION     DAZUDJ010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2062
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.243"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            778..1755
                     /locus_tag="ACHY1N_005303"
     CDS             778..1755
                     /locus_tag="ACHY1N_005303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFS4047404.1"
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNT
                     LSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVE
                     LPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSA
                     YYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPA
                     PISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPR
                     LKAPNDESKENPLPPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
BASE COUNT          553 a          509 c          489 g          511 t
ORIGIN      
        1 gtctccagga ttcccggggc ggttcagtgg ataaatgctt attacaacgt ttatcgacct
       61 catacaaaca atggtggttt atcgccttgc cgcatgaaga aaaatggaaa caggttattc
      121 cggtgtcctg attttatgat ccactacaca ttcctgacga acgccactgc ataaatcaca
      181 ttgcacatcc tcagagagta cgcagtatag gaggggtata tatacattat cggtatatca
      241 ggcgacttct gtctgtatgt tgtcggtgct cgccgcagac cggtgaccgg gcgaagcccg
      301 cgaaccggcg aggaagcgca atgtatctgt agttacagtg agcagatacg ccctgaagct
      361 tcctcataaa acagttgtgt aaactgtttt cccggaatga tttatccaca tatccggcgg
      421 cccgatccag taaacagatc cataaatgat caagaaatga tccattaaag atccccatat
      481 cgctgcaaac cttgtcactc atgctccggg accacgatca cataagctgt ggcatgtttc
      541 tgataaactg tagcaggatc atgataagct gtattcagta atgtatatac tgtagtaagt
      601 taatgacata aattatggtc agtacgccag gctcagctgt taaatacaga ctgcaggttt
      661 ttcttcagtc agttgacggg gttctgacac tcaattttct gtttattctt ttactgtcca
      721 caggcaggag gctttctgga aaacgaaaat tcagacatca aaaaactgtt cggcgaggtg
      781 gataagtcgt ccggtgagct ggtgacactg acaccaaaca ataacaacac cgtacaacct
      841 gtggcgctga tgcgtctggg cgtttttgta ccgaccctta aatcactgaa gaacagtaaa
      901 aaaaatacac tgtcacgtac tgatgccacg gaagagctga cacgtctttc cctggcccgt
      961 gctgagggat ttgataaggt tgagatcacc ggcccccgcc tggatatgga taacgatttc
     1021 aagacctggg tgggaatcat tcattccttt gcccgccata acgtaattgg tgacaaagtt
     1081 gaactgcctt ttgtcgagtt tgcaaaactg tgtggtatac cttcaagcca gtcatcccgc
     1141 aggctgcgtg agcgcatcag cccttccctg aaacgcattg ccggtaccgt gatctccttt
     1201 tcccgcaccg atgagaagca cacccgggaa tatatcaccc atctggtaca gtcagcctac
     1261 tacgatactg aacgggatat tgttcagtta caggctgatc cccgcctttt tgaactgtac
     1321 cagtttgacc ggaaagtgct gctgcagctc aaggccatca atgccctgaa gcgacgggag
     1381 tccgcccagg cactttacac ctttatagag agcctgcccc gggatccggc accgatatcg
     1441 ctggcgcggc tgcgtgcccg cctcaatctg aagtctcctg tattttccca gaaccagacg
     1501 gtcagacggg caatggagca gttgcgcgag attggatatc ttgattacac ggagatccag
     1561 cgggggcgga caaaattctt ctgtattcac taccggcgtc cccggttaaa agcgccgaat
     1621 gatgagagta aggaaaatcc gttgccacct tcacctgcgg aaaaagtcag tccggagatg
     1681 gcggagaaac ttgccctgct tgaaaaactg ggcatcacgc tggatgacct ggaaaaactc
     1741 ttcaaatccc gctgaacata aactgtagtc agtgaagagt gctcctttac tgactacagc
     1801 ttatattatc aggtgcagtg agtggtctgc tcactgcagt ttatatgtaa gcgtacagcc
     1861 tgaaccgtct ggtcagaatc tgacgaatta gacaaagtgg tgtccaccaa ataagtagtg
     1921 ggaaccaaag tgtcagatat gcagaaaaat gtgactcccg gcaggcgaaa aggctgccct
     1981 aattatcctc ccgaatttaa acagcagctc gttgctgcct cctgtgaacc cgggatatcc
     2041 atctcaaaac ttgctcttga aa
//
LOCUS       DAZUDJ010000239         2050 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.244, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000239 DAZUDJ010000000
VERSION     DAZUDJ010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2050
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.244"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..831
                     /locus_tag="ACHY1N_005304"
     CDS             <1..831
                     /locus_tag="ACHY1N_005304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HFS4047405.1"
                     /translation="GGETRVLRPGYVKPKHEFNYQQAVERLPGEDPAQLNDPAYRRLR
                     IITDNLKQEEHAIVQVEEMQAVNAVLYGKYTMEGDQFDTVEVDFGRSEGNNIEQADGK
                     KWSEQDRDTFDPTHDIDLYCDQASGLVNIAIMDGTVWRLLNGFKLFREKLDTRRGSNS
                     QLETAVKDLGAVVSFKGYYGDLAIVVAKTSYVAEDGTEKRYLPEGTLVLGNTAADGIR
                     CYGAIQDAQALSEGVVASSRYPKHWLTVGDPAREFTMTQSAPLMVLPDPDEFVVVQVK
                     "
     gene            883..1266
                     /gene="gpFI"
                     /locus_tag="ACHY1N_005305"
     CDS             883..1266
                     /gene="gpFI"
                     /locus_tag="ACHY1N_005305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001355131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HFS4047406.1"
                     /translation="MATKEENQKRLRQLAGLLGREADMSGSAADIAQRVSEWEEELAA
                     SREGIMPGDESGPEQNHTDDGEQLHNTDATDDVKAVRVRQCLHVMGYCPETGRPVELT
                     YRGMRVLVPSPLATAMIQHGTAEHA"
     gene            1259..1612
                     /locus_tag="ACHY1N_005306"
     CDS             1259..1612
                     /locus_tag="ACHY1N_005306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HFS4047407.1"
                     /translation="MRDFQNAFDAALAGVDSTIVEVMGLCAQFTSGAQCGSEVQGVFD
                     DPESLGFAGSGVRIEGSCPSLFVRTDTVRAVRRGDTLTINGETFWVDRVSPDDGGSCY
                     LWLNRGQPPAVNRRR"
     gene            1627..>2050
                     /locus_tag="ACHY1N_005307"
     CDS             1627..>2050
                     /locus_tag="ACHY1N_005307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047408.1"
                     /translation="MAIKGLDQAIENLSRVRKNAIPAASAMAINRVATTAINQSSSQV
                     ARETRVSRKLVKERSRLKRATVRNPNARIIVNRGDLPVIKLGIRMPGRRPDSILKAGQ
                     HRYQRAFIQRLKNGRWHVMQRVAGKNRYPIDVVKIPMAA"
BASE COUNT          464 a          474 c          658 g          454 t
ORIGIN      
        1 ggtggtgaaa cccgcgtgtt acgtccgggc tacgtcaagc cgaaacacga atttaattac
       61 cagcaggcgg ttgagcgtct tcccggtgaa gatccggctc aactgaacga cccggcctac
      121 cgtcgtctgc gtatcatcac cgataacctc aaacaggaag agcatgccat tgtccaggtg
      181 gaagaaatgc aggcggtgaa tgccgtgctg tatggcaaat acaccatgga aggggatcag
      241 tttgatactg tcgaggtgga ttttggacgc tctgaaggaa ataacattga gcaggccgac
      301 ggtaaaaaat ggtctgagca ggaccgtgat acgtttgatc cgacgcatga tattgacctc
      361 tactgcgatc aggccagcgg tcttgtgaat attgccatta tggacggtac tgtctggcgt
      421 ctgctgaatg gttttaagct gttccgcgaa aaactggata cccgtcgcgg ctcaaattca
      481 caactcgaaa cggcagtgaa agacctgggg gcggtggtgt ctttcaaagg gtattacggc
      541 gatctggcca ttgtggtggc gaaaacgtct tatgtggcag aggacggtac cgaaaaacgt
      601 tatctgccgg agggcacgct ggtcctggga aatacggctg cagatgggat ccgttgttac
      661 ggtgccattc aggatgcgca ggcgttgtcc gaaggtgtgg tggcttcttc ccgttacccg
      721 aaacactggc tgaccgtggg cgatccggcc cgtgaattta ccatgacgca gtccgcaccg
      781 ctgatggtgc tgccggatcc ggatgagttt gtggtggtgc aggtgaaata atccgtgagc
      841 gggggcgaaa tgcccccgtg tcttttttca cagggggctg atatggcaac aaaagaagaa
      901 aatcagaaac gtcttcgtca actggctggc ctgctggggc gcgaggcgga tatgtcgggg
      961 agtgctgcgg atattgcgca acgtgtgtct gagtgggaag aggagcttgc tgcttcccgg
     1021 gagggcatta tgcctggtga tgagagcggg cctgagcaaa atcacacaga cgatggtgag
     1081 cagttgcaca acactgatgc tacggatgat gttaaagcgg tccgtgtgcg gcaatgcctg
     1141 catgtgatgg ggtattgccc ggagacaggc cgtcccgttg aactgacgta ccggggcatg
     1201 cgtgttctgg tgccatcacc actggcgaca gccatgatac agcacggaac ggctgagcat
     1261 gcgtgatttt cagaatgcct ttgatgcagc ccttgccggg gtggacagca cgattgttga
     1321 agtgatgggg ctctgtgcgc agttcacctc gggggcacag tgtggcagcg aagttcaggg
     1381 ggtttttgac gatccggagt cgctggggtt tgccggtagc ggggtccgta ttgaaggaag
     1441 ctgcccgtca ttatttgtac ggacggatac ggttcgtgct gtgcggcgtg gtgacacgct
     1501 gaccattaat ggtgagacat tctgggtgga tcgtgtttct ccggatgacg ggggcagttg
     1561 ttatctctgg ctcaaccgtg ggcaaccacc ggcagttaac cggcgacgat aaacgcaggg
     1621 tgaattatgg cgataaaagg gcttgatcag gcgattgaaa atctgagccg ggttcgtaaa
     1681 aacgccattc cggcggcttc agcaatggcc attaaccgcg tggccacaac ggcgattaat
     1741 cagtcttcgt cacaggttgc ccgggagacc agggtgagcc ggaaactggt aaaggaacgg
     1801 tccagactga aacgggccac ggtcagaaat ccgaatgcca gaattatcgt taaccgcggt
     1861 gatctcccgg tgattaagct ggggatcagg atgccggggc gtcgtccgga cagcatactc
     1921 aaagccggtc agcatcgtta tcagcgggca tttattcagc gattaaaaaa tggtcgctgg
     1981 catgtcatgc agcgtgtggc cgggaaaaac cgttacccca ttgatgtggt gaaaatcccg
     2041 atggcggccc
//
LOCUS       DAZUDJ010000240         2018 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.245, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000240 DAZUDJ010000000
VERSION     DAZUDJ010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2018
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.245"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>2018
                     /locus_tag="ACHY1N_005308"
     CDS             <1..>2018
                     /locus_tag="ACHY1N_005308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4047409.1"
                     /translation="TSLAVATGALAYAWYQGDSTLSAFNKTLVLSGNQSGLTADRMLT
                     LSRAGQAAGLTFNQASESLAALVNVGVRGGEQFDAINQSVARFASASGVEVDKVAEAF
                     GKLTTDPTSGLMAMARQFHNVTAEQIAYVAQLQRSGDEAGALQAANEAATKGFDDQTR
                     RLKENMGTLETWADRTARAFKSMWDAVLDIGRPDTAQEMLIKAEAAFKKADDIWSLRK
                     DDYFVNDEARARYWDDREKARLALEAARKKAEQQSQQDKNAQQQSDTEASRLKYTEEA
                     QKAYERLQTPLEKYTARQEELNKALKDGKILQADYNTLMAAAKKDYEATLKKPSAVKV
                     SAGERQEDRAHAALLALETELRTLEKHSGANEKISQQRRDLWKAENQYAVLKEAATKR
                     QLSEQEKSLLTHEKETLEYKRQLAELGDKVEHQKRLNELAQQAARFEQQQGAKQAAIS
                     AQARGLTDRQAQRESEEQHLRDVYGDNPDALAKATSALKNTWSAEEQLRGSWMAGLKS
                     GWGEWAESATDSFSQVKSVATQTFDGIAQNMAAMLTGSEQNWRSFTRSVLSMMTEILL
                     KQAMVGIVGSIGSAIGGAFGGGASASTGTAIQAAAANFHFATGGFTGTGGKYEPAGIV
                     HRGEFVFTKEATSRIGVGNLYRLMRGYAEGGYVGGAGSPAQMRRTEGI"
BASE COUNT          484 a          487 c          687 g          360 t
ORIGIN      
        1 cacctcgctg gcggtggcga caggtgcgct ggcgtacgcc tggtaccagg gggattccac
       61 gctttcagcg tttaataaaa ccctggttct ttccggtaat cagtccggac tgactgccga
      121 tcgcatgctg acgctctcca gagccggaca ggccgcaggg ctgacgttta accaggcgag
      181 tgagtcactg gcagccctgg tgaatgtcgg tgtgcgtggt ggtgaacagt ttgatgccat
      241 caaccagagt gtcgcgcgtt ttgcttctgc atccggtgtg gaggtggaca aggttgcaga
      301 ggctttcgga aaactgacca ccgacccgac gtcggggctg atggcgatgg cacgccagtt
      361 ccataacgtg acggcggagc agattgcgta tgttgctcag ttgcagcgtt ccggcgatga
      421 agccggggca ttgcaggcgg cgaacgaggc cgcgacgaaa ggatttgatg accagacccg
      481 ccgcctgaaa gagaacatgg gtacgctaga gacctgggca gacaggacag cacgggcatt
      541 caaatccatg tgggatgcgg tgctggatat tggtcgtcct gataccgctc aggagatgct
      601 gattaaggca gaggctgcgt ttaagaaagc ggacgacatc tggagtctgc gcaaggatga
      661 ttattttgtt aacgatgaag cgcgggcgcg ttactgggat gatcgtgaaa aggcccgtct
      721 tgcgcttgaa gccgcgagaa agaaggctga acagcagagt caacaggaca aaaatgcgca
      781 gcagcagagc gatactgaag cgtcacggct gaaatatacc gaagaggcgc agaaagctta
      841 cgaacggctg cagacgccgc tggagaaata taccgcccgt caggaagaac tgaacaaggc
      901 actgaaggac gggaaaatcc tgcaggcaga ttacaacacg ctgatggcgg cggcgaaaaa
      961 ggactatgaa gcgacgctga aaaagccatc tgctgtgaag gtgtctgccg gtgagcgcca
     1021 ggaagaccgg gcgcatgcag ccctgctggc gcttgaaacc gagctccgga cgctggaaaa
     1081 acacagcggt gcgaatgaga aaatcagcca gcagcgtcgc gatttatgga aagcggaaaa
     1141 tcagtatgcg gtcctgaaag aggcagccac gaaacggcag ttatctgagc aggaaaaatc
     1201 cctgctgacc catgagaaag agacgctgga gtacaaacgc cagctggctg agctgggaga
     1261 caaagttgaa caccagaaac ggctgaatga gctggcacag caggctgcgc ggtttgagca
     1321 gcagcagggc gcgaagcagg cggcaatcag tgcccaggcg cggggcctca ccgaccgtca
     1381 ggcgcagcgg gagtcggaag agcagcacct tcgtgacgtg tacggtgata atccggatgc
     1441 gctggcgaag gccacatctg cactgaagaa cacctggtct gcggaggagc agcttcgtgg
     1501 aagctggatg gccggtctga agtccggctg gggcgagtgg gcagaaagtg cgacggacag
     1561 tttttcgcag gttaaaagcg tggccacgca gacctttgac ggtattgcac agaatatggc
     1621 agcgatgctg accggcagtg agcagaactg gcgcagcttc acccgttccg tgctgtccat
     1681 gatgacagaa attctgctta agcaggcaat ggtggggatt gtcgggagta tcggcagcgc
     1741 cattggcggt gctttcggtg gtggtgcgtc tgcctccacg gggacggcca ttcaggctgc
     1801 ggcggcgaac ttccatttcg cgaccggggg atttacgggg acggggggta aatatgaacc
     1861 tgcgggaatt gttcatcgcg gggagtttgt cttcacgaag gaagcaacca gccggattgg
     1921 cgtcggcaac ctgtaccgcc tgatgcgggg ctatgcggaa ggtggttatg tgggcggtgc
     1981 cggaagtccg gcgcagatgc ggcggacgga aggcatta
//
LOCUS       DAZUDJ010000241         1967 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.246, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000241 DAZUDJ010000000
VERSION     DAZUDJ010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1967
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.246"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            3..536
                     /locus_tag="ACHY1N_005309"
     CDS             3..536
                     /locus_tag="ACHY1N_005309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047410.1"
                     /translation="MAIKGLDQAIDNLSRVRKNAIPAASVMAINRVATTAINQSSSQV
                     ARETKVRRKLVKERSRLKRATVRNPNARIIVNRGDLPVIKLGIRMPGRRPNSILKAGQ
                     HRYQRAFIQRLKNGRWHVMQRVAGKNRYPIDVVKIPMAAPLKQAFDENVDRIRRERLP
                     KELAYALKQQLRIAIKR"
     gene            533..928
                     /locus_tag="ACHY1N_005310"
     CDS             533..928
                     /locus_tag="ACHY1N_005310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail U family protein"
                     /protein_id="HFS4047411.1"
                     /translation="MKHTDIRAAVLDALEQHEHGATLFDGRPVVFDEEDFPAIAVYLT
                     DAEYTGEELDADTWRATLHIEVFLPAQVPDSELDQWMESRIYPAMTAIPALAGLITTM
                     VTQGYEYRRDDDMALWSSADLTYSITYEM"
     gene            936..1688
                     /locus_tag="ACHY1N_005311"
     CDS             936..1688
                     /locus_tag="ACHY1N_005311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047412.1"
                     /translation="MATPNPLEPVKGAGTTLWVYNGKGDAYANPLSDDDWQRLAKVKD
                     LTPGEMTAESYDDNYLDDEDADWTATGQGQKSAGDTSFTLAWKPGEEGQKGLIGWFES
                     GDVRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSKITP
                     VSAIKVTPTSGTVAKGKTTTLTVSFEPESATDKTFRAVSTDPSKATISVKDMTITVNG
                     VATGKVQIPVVSGNGQFAAVAEVTVTEAGAAG"
     gene            1702..>1967
                     /locus_tag="ACHY1N_005312"
     CDS             1702..>1967
                     /locus_tag="ACHY1N_005312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HFS4047413.1"
                     /translation="MFLKTEQFEYNGVSVTLSELSALQRIEHLALLKRRAEQAESSGN
                     LQVSVEDLVRTGAFLVAMSLWHNHPQKTASPSMNEAVMQIEQEVL"
BASE COUNT          510 a          454 c          591 g          412 t
ORIGIN      
        1 ttatggcgat aaaagggctt gatcaggcga ttgacaatct gagccgggtt cgtaaaaacg
       61 ccattccggc ggcttcagta atggccatta accgcgtggc cacaacggcg attaatcagt
      121 cttcatcaca ggttgcccgg gagacaaagg ttcgccggaa actggttaag gaacggtcca
      181 gactgaaacg ggcgacggtc agaaatccga atgccagaat tatcgttaac cgcggtgatc
      241 tccctgtgat taagctgggg atcaggatgc cggggcgtcg cccgaacagc atacttaaag
      301 ccggtcagca tcggtatcag cgggcattta ttcagcgatt aaaaaatggt cgctggcatg
      361 tcatgcagcg tgtggccggg aaaaaccgtt accccattga tgtggtgaaa atcccgatgg
      421 cggccccact gaaacaggca tttgatgaga atgttgaccg tatccggcgt gaacgcctgc
      481 ctaaagaact ggcatacgcg ctgaaacaac aactgaggat tgcaataaaa cgatgaaaca
      541 cactgacatt cgtgccgcag tgctggatgc actcgagcag catgaacacg gggcgacgct
      601 gtttgatggt cgccccgttg tttttgacga agaggatttt cctgcgatcg cggtttatct
      661 gacggatgca gagtataccg gtgaagagct ggatgcagat acctggcggg ccacgctgca
      721 tattgaggtg tttttaccgg cacaggtacc ggattcagag cttgatcagt ggatggaaag
      781 ccggatttac ccggcgatga ccgcgatccc ggcactggca ggactgatta ccacgatggt
      841 tacgcagggc tatgagtatc gtcgtgatga cgatatggcg ttatggagtt ctgcagatct
      901 gacttattcc attacatacg agatgtgagg acgatatggc aacaccaaat ccccttgagc
      961 cggtaaaagg tgccggtacc actctgtggg tttacaacgg caagggtgat gcttatgcaa
     1021 acccgttgtc agacgatgac tggcagcgac tggctaaggt gaaggatctg acgccgggcg
     1081 agatgacggc agaatcctac gatgataact acctggatga tgaagacgcg gactggaccg
     1141 cgaccgggca ggggcagaaa tctgcaggtg ataccagttt tacgctggcc tggaaaccgg
     1201 gagaggaagg ccagaaaggg cttataggct ggtttgaaag cggcgatgtc cgggcctata
     1261 aaatccgttt tccgaatggc acggtggatg tgtttcgtgg ctgggtcagc agtatcggta
     1321 aggccgtgac ggcgaaagaa gtgatcaccc gcacggtgaa agtcactaac gtgggtaaac
     1381 cttctgtagc ggaagaacgc agcaaaatta cgccggtcag tgcgattaag gtgacgccga
     1441 catccggtac ggtggcaaaa gggaaaacaa ccaccctgac ggtttctttt gagccggaaa
     1501 gtgcaacaga caagacgttc agagcggttt ccaccgatcc gtcgaaagcc accattagtg
     1561 tgaaagatat gacaattacg gtaaacggcg tggcgacagg taaggtgcag atccctgtgg
     1621 tgagcggaaa tggtcagttc gccgcagtgg ctgaagtcac cgttactgaa gcgggcgctg
     1681 cagggtaaac ggaggtcata catgtttctg aaaacagaac aatttgaata taacggtgtg
     1741 tctgtcacgc tttccgaatt gtctgcgctg cagcgtattg agcatcttgc cctcctgaaa
     1801 cggcgtgcag aacaggcaga atccagcggc aacctgcagg taagcgtgga agatctcgtc
     1861 agaaccggcg cgtttctggt ggcgatgtcc ctgtggcata accatccgca gaaaacggca
     1921 tcaccgtcaa tgaatgaggc cgtgatgcag atcgaacagg aggtgct
//
LOCUS       DAZUDJ010000242         1909 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.247, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000242 DAZUDJ010000000
VERSION     DAZUDJ010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1909
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.247"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..114
                     /locus_tag="ACHY1N_005313"
     CDS             <1..114
                     /locus_tag="ACHY1N_005313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HFS4047414.1"
                     /translation="TLLGERIMDRMTMNGGRWVTFNWDSWRPNVSNQRVVK"
     gene            136..852
                     /locus_tag="ACHY1N_005314"
     CDS             136..852
                     /locus_tag="ACHY1N_005314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310231.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
                     /protein_id="HFS4047415.1"
                     /translation="METVFDALKALKKASSQVVASRLGISREDAVNELWKLKRRGEAD
                     NKGSMWWLIQAGESEPVSPVPKVTAQMLTEAIEHHGPQTADELALMFGITSRRANSSL
                     AMAISKGRLIRVNQGGKFRYCIPGADLPAEPKAASIAETDGKAFPQPAGVALPVGEAE
                     TQEEIKTESVAVTVQSQPSFTRKHPDGLILPSLHVANRELRRAKGQVQKWERVCAALR
                     ELNKCRDILRDITATREQQR"
     gene            885..1166
                     /locus_tag="ACHY1N_005315"
     CDS             885..1166
                     /locus_tag="ACHY1N_005315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFS4047416.1"
                     /translation="MILRQCAGTRKVKSVGALIGRTEAAVRTKARELGISMMLRGDFH
                     PSAKYSQRDIELARQLHQRGMQRREIARKLGMPLRIVNNYVYFDRRVSA"
     gene            1163..1390
                     /locus_tag="ACHY1N_005316"
     CDS             1163..1390
                     /locus_tag="ACHY1N_005316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047417.1"
                     /translation="MKILYQDYGPVGQVVISSTVMEFRKHNRVVDAVLLTCPGISASR
                     AGVFIMKTKLYGSKAWIKKAYRVALQEVNSE"
     gene            1383..1694
                     /locus_tag="ACHY1N_005317"
     CDS             1383..1694
                     /locus_tag="ACHY1N_005317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047418.1"
                     /translation="MSKIKEMPVVRDGYGYWTHPEYEKFCDGREYISTEEFNAWMEEN
                     NLQYVLCFRDEGCADLDACDADISAWEPERPEGDGWFIGSIHDTEDGPVCVWLRNKAE
                     A"
     gene            1822..>1909
                     /locus_tag="ACHY1N_005318"
     CDS             1822..>1909
                     /locus_tag="ACHY1N_005318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4014 family protein"
                     /protein_id="HFS4047419.1"
                     /translation="MKHYLEKNYPRKSRTTEFLFFILFIVLMI"
BASE COUNT          528 a          375 c          574 g          432 t
ORIGIN      
        1 acgcttcttg gtgagaggat tatggaccgc atgaccatga acggtggtcg gtgggtgacg
       61 tttaactggg atagctggcg tccaaatgtc agcaatcaga gggttgtaaa gtaatttttg
      121 ttggaggacg ttttaatgga aactgtattt gacgcactga aagcactgaa aaaagcctct
      181 tcacaggtag tggcatcgcg ccttggaatc agccgcgaag atgctgtcaa cgaactgtgg
      241 aaactgaagc gccgtggtga agcggataac aagggttcga tgtggtggct gattcaggct
      301 ggtgaaagtg aaccagtgtc accggtaccg aaagtgacag cgcaaatgct gactgaggcg
      361 attgaacatc atggcccaca aacggcggat gagctggcac tgatgttcgg gattacctcc
      421 cgccgggcga attcatcact ggccatggca atcagcaaag ggcgtctgat tcgcgtgaat
      481 cagggcggta aatttcggta ctgcataccg ggcgctgatt taccggcaga gccgaaagcc
      541 gcatccatag cggaaacgga tggtaaagcc tttcctcagc cagcaggtgt tgcgttacca
      601 gtcggggaag cggaaacaca ggaagaaata aaaacggaaa gtgtggcggt cacagtgcag
      661 tcacagccgt cgttcaccag aaagcatccg gatggtctga ttttaccatc gctgcatgtg
      721 gctaaccgcg agctgcgccg ggcaaaaggt caggttcaga agtgggagcg agtctgcgcc
      781 gcgctgcggg agctgaacaa gtgccgggat attctccggg atattaccgc caccagagaa
      841 cagcagcggt gagtgggtgg aagacgtggt gccgggcgga aatcatgata ctccggcagt
      901 gtgcgggaac gaggaaggta aaaagcgttg gcgcacttat cggacgaact gaagcggcag
      961 tgagaacgaa ggcacgggag ctgggcatca gcatgatgtt acgtggtgat tttcacccgt
     1021 cggcaaaata ttctcagcgt gatattgagc tggcgcggca actgcatcag agaggcatgc
     1081 aaagaaggga aattgccaga aaattaggca tgccgctgcg catagtgaat aactacgttt
     1141 atttcgacag gagggtgtct gcgtgaaaat cctgtatcag gattacggcc cggtggggca
     1201 ggtggttatc agcagtactg taatggagtt tcggaagcat aaccgtgtgg tggatgctgt
     1261 gctgttaacc tgtccgggga tatcggcgag tcgtgcaggt gtgtttatta tgaagacgaa
     1321 attatatggc agtaaggcgt ggataaagaa ggcgtatcgt gtagcgttgc aggaggttaa
     1381 cagtgagtaa aattaaagaa atgccggtag ttcgtgacgg atatggctac tggacacatc
     1441 ctgaatatga aaaattctgt gatggtcggg aatatatttc aacggaagag tttaacgcct
     1501 ggatggagga aaataatctt caatacgtcc tctgcttcag agatgaagga tgtgctgacc
     1561 ttgatgcgtg tgatgctgat atttctgcat gggaaccgga acgaccagag ggcgatggct
     1621 ggtttattgg ttccattcat gatacggaag atggcccggt ttgtgtctgg ttgcgaaata
     1681 aggctgaagc ataaaggcga taaaccaact aacaactaaa tactgaagat ttaaatcaga
     1741 aacgattttt attaaatcct taaccggagg gattcctgca ccctcagaac atcaggaggc
     1801 cgcccgaaag ggcggtaaga aatgaaacat tatttagaaa aaaattaccc acgaaagagc
     1861 agaacaacag agtttctgtt tttcattctg tttatagtgt tgatgatac
//
LOCUS       DAZUDJ010000243         1903 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.248, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000243 DAZUDJ010000000
VERSION     DAZUDJ010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1903
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.248"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1903
                     /locus_tag="ACHY1N_005319"
     CDS             <1..>1903
                     /locus_tag="ACHY1N_005319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4047420.1"
                     /translation="GKLTADKVVPALISQLGTLRDEYAAMPETVSDGITKVENAFMAW
                     VGGANEASGVTKTLSGVLNGVAGQIDNVATAVGALVAVGVARYFGNMASGAMSATAGL
                     VTAARNEVALAEAQFRGTQIATARARAAVYCAQQAVAAARGTEMQIAAEARLAATQER
                     LNRNIAARSAAQNALNSTTAVGSRLMSGALGLVGGVPGLVMLGAAAWYTLYQNQEQAR
                     ESARQYALTIDEIAHNTPSMSLPEASDNEGRTRAALTEQKRLIDEQSSRVKSLQEQIA
                     GYQYVLANPGWTTGDGFMINHLTSVKTVTEGLAQATEQLAVEQSRLAQMQEKAQSIQD
                     VLAGLEDRRVALIRQQAAEQNKVYQSMLVMNGQHTEFNRLLGLGNELLQQRQGLVNVP
                     LRLPQATLDDKQQSALTKTERELALSRLKGEEKERVRLGYAADDLGFVGDPYQEARQR
                     YISNALEAWRNNEANKPKSRGGKSETEKAEDSFSRLLKQQKEQLALVGQNTELAKLKY
                     QTAQGELKTLTEMQKQELLRNAALIDQQKIREQLRSREETLKNENAAARASNDAELLG
                     YGQGERARERMRELQQIRDSFRQKDADLQSQYQTGDISEDFYRQALAQNAQYLSERLK
                     EQEAFYAESD"
BASE COUNT          480 a          450 c          636 g          337 t
ORIGIN      
        1 ggcaaactga cggcggataa agtcgtgccc gcgttaatca gccagctggg gacattgcgt
       61 gatgaatatg ccgccatgcc agaaacggtc tctgacggga tcacaaaggt ggaaaacgcc
      121 tttatggcct gggtgggtgg tgcgaatgag gccagcgggg tgacaaaaac gctctccggc
      181 gtgctgaacg gtgttgccgg acagattgat aatgtggcaa cagccgtggg ggcactggtt
      241 gccgtcgggg ttgcccggta ctttggcaat atggcctccg gagcgatgtc tgccacggca
      301 ggacttgtga ctgctgcacg taatgaagtt gcactggcgg aagcacagtt caggggaacg
      361 cagattgcca cggcgcgggc aagagcagcc gtgtactgtg ctcagcaggc cgtggcggca
      421 gcccgcggga cggagatgca gattgcagca gaggcccgtc tggcggccac acaggaacgc
      481 ctgaacagaa atattgctgc cagaagcgcc gcccagaatg cgctgaacag tacaacggcg
      541 gtgggctcac gtctgatgag cggtgcgctg gggctggttg gtggcgtacc cggactggtg
      601 atgctggggg ctgcagcatg gtacacgctg taccagaatc aggagcaggc cagggagtct
      661 gcgcgccagt atgcactgac gatagatgaa atcgcgcata acacgccgtc aatgtctttg
      721 cctgaagcct cagataatga aggacgaaca cgggcggcgc tgacagagca gaagcggctg
      781 attgatgagc agtccagtcg ggtgaaatcc ctgcaggaac aaatcgccgg gtatcagtat
      841 gttctggcga accctggctg gacgaccggt gacggattca tgataaacca tctgacatcg
      901 gtgaagaccg taacggaagg gcttgctcag gcaacagagc agcttgccgt tgagcagtcc
      961 cgtctggcac agatgcagga aaaagcgcag tccattcagg atgtgcttgc cgggctggaa
     1021 gaccgtcgtg tggcgttaat tcgtcagcag gcggcagagc agaataaggt gtaccagtcc
     1081 atgctggtta tgaacggtca gcatacggaa ttcaaccgtc tgctggggct gggtaatgaa
     1141 ctgcttcagc agcggcaggg gctggtgaat gtgccgttac ggctgccaca ggccactctg
     1201 gatgataaac agcagagtgc cctgacaaaa acagagcgtg agctggccct gtccagactg
     1261 aaaggggaag aaaaagagcg tgtccggctg gggtatgcgg cggatgacct cggttttgtg
     1321 ggtgatccgt atcaggaggc gagacaacgt tatatcagta atgccctgga agcctggcgc
     1381 aataacgagg cgaataaacc caaatcccgg ggtggaaaat cagagacgga aaaagcggaa
     1441 gacagttttt cccggctgct gaagcagcag aaagagcaac tggcactggt ggggcagaat
     1501 acagagctgg cgaagctgaa ataccagact gcgcagggcg aactgaaaac cctgacggaa
     1561 atgcagaagc aggagctgct gcgtaatgcg gccctgattg accagcaaaa aatccgggaa
     1621 cagttgcgat cccgggaaga gacactaaag aatgagaatg cggctgcgcg tgcgtcgaat
     1681 gatgctgaac tgctggggta cgggcagggg gaacgagcca gagaacgcat gcgggagttg
     1741 cagcagatcc gcgacagctt ccgccagaag gatgcggacc ttcagtctca gtatcagacc
     1801 ggggatatca gtgaggattt ttacagacag gctctggcgc agaatgcaca gtatctgagt
     1861 gaacgtctga aagagcagga agccttttat gccgaatcgg atg
//
LOCUS       DAZUDJ010000244         1903 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.249, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000244 DAZUDJ010000000
VERSION     DAZUDJ010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1903
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.249"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1903
                     /locus_tag="ACHY1N_005320"
     CDS             <1..>1903
                     /locus_tag="ACHY1N_005320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4047421.1"
                     /translation="GQLTADKVVPALISQLGVLRDEYAAMPETVSGSITKVENAFMAW
                     VGGVNEASGVTKTLSGVLNGVAGQIDNVATAVGALVAVGVARYFGNMASGAMSATAGL
                     VTAARNEVALAEAQFRGTQIATARARAAVYRAQQAVAAARGTEMQIAAEARLAATQER
                     LNRNIAARSAAQNALNSTTAVGSRLMSGALGLVGGVPGLVMLGAAAWYTLYQNQEQAR
                     ESARQYALTIDEIAHKTPSMSLPEASDNEGRTRAALTEQNRLIDEQASRVKSLQEKIA
                     GYQYVLANPGWTTGDGFMINHLTSVKTVTEGLAQATEQLAVEQSRLAQMQEKAQSIQD
                     VLAGLEDRRVALIRQQAAEQNKVYQSMLVMNGQHTEFNRLLGLGNELLQQRQGLVNVP
                     LRLPQATLDDKQQSALTKTERELALSRLKGEEKERARLGYAADDLGFVGDSYQEARQR
                     YISNALEAWRNNEANKPKSRGGKSETEKAEDSFSRLLKQQKEQLALAGQNTELAKLKY
                     QTAQGELKTLTEMQKQELLRNAALIDQQKIREQLRSREETLKNDNVAARASNEAELLG
                     YGQGERARERMRELQQIRDSFRQKDADLQSQYQTGDISEDFYRQARAQNAQYLSERLK
                     DQAAFYAESD"
BASE COUNT          478 a          454 c          635 g          336 t
ORIGIN      
        1 ggtcaactga cggcggataa agtcgttcct gcgttaatca gccagctggg ggtattgcgt
       61 gatgaatatg ccgccatgcc agaaacggtt tccggtagta tcacgaaggt ggaaaacgcc
      121 tttatggcct gggtgggcgg agtgaatgag gccagcgggg tgacaaaaac gctctccggc
      181 gtgctgaacg gtgttgccgg acagattgat aatgtggcaa cagctgtggg tgcgctggtt
      241 gccgtcgggg ttgcccggta ctttggcaat atggcctccg gagcgatgtc tgccacggca
      301 ggacttgtga cggctgcacg taatgaagtt gcactggcgg aagcacagtt caggggaacg
      361 cagattgcca cagcgcgggc aagggcagcc gtgtaccgtg ctcagcaggc cgtggcggca
      421 gcccgcggga cggagatgca gattgctgca gaggcccgtc tggcggccac acaggaacgc
      481 ctgaacagaa atattgctgc cagaagcgcc gcccagaatg cgctgaacag tacaacggcg
      541 gtgggctcac gtctgatgag cggtgcgctg gggctggttg gtggcgtacc cggactggtg
      601 atgctggggg ctgcagcatg gtacacgctg taccagaatc aggagcaggc cagggagtct
      661 gcgcgccagt atgcactgac gatagatgaa atcgcgcata aaacgccgtc aatgtctttg
      721 cctgaagcct cagataatga aggacgaaca cgggcggcgc tgacagagca gaaccggctg
      781 attgatgaac aggccagtcg ggtgaaatcc ctgcaggaaa aaatcgcagg atatcagtat
      841 gttctggcga acccgggctg gacgaccggt gacggattca tgataaacca tctgacctcg
      901 gtgaagaccg taacggaagg gcttgctcag gcaacagagc agcttgccgt tgagcagtcc
      961 cgtctggcac agatgcagga aaaagcgcag tccattcagg atgtgcttgc cgggctggaa
     1021 gaccgtcgtg tggcgttaat tcgtcagcag gcggcagagc agaataaggt gtaccagtcc
     1081 atgctggtta tgaacggtca gcatacggaa ttcaaccgtc tgctggggct ggggaatgaa
     1141 ctgcttcagc agcgtcaggg gctggtgaat gtaccgttac ggctgccaca ggccaccctg
     1201 gatgataaac agcagagtgc cctgacaaaa acagagcgtg agctggccct gtcccgactg
     1261 aagggggagg aaaaagagcg tgcccggctg gggtatgcgg cggatgacct tggttttgtg
     1321 ggggattcgt atcaggaggc gagacagcgt tatatcagta atgccctgga agcctggcgt
     1381 aataacgagg cgaacaaacc taaatcccgg ggtggaaaat cagagacgga aaaagcggaa
     1441 gacagttttt cccggctact gaagcagcag aaagagcaac tggcactggc gggtcagaat
     1501 acagagctgg cgaagctgaa gtaccagact gcgcagggcg aactgaaaac cctgacggag
     1561 atgcagaagc aggaactgct gcgtaacgcg gccctgattg accagcaaaa aatccgggaa
     1621 cagttgcgat cccgggaaga gaccctgaag aatgataatg tggctgcgcg tgcatcaaat
     1681 gaagccgaac tgctgggata cgggcaggga gaacgagcca gggaacgcat gcgggagttg
     1741 cagcagatcc gcgacagctt ccgccagaag gatgcggacc ttcagtctca gtatcagacc
     1801 ggggatatca gtgaggattt ttacagacag gcacgggcac agaacgcgca gtatctgagc
     1861 gaacgcctta aggaccaggc agccttttat gccgaatcgg atg
//
LOCUS       DAZUDJ010000245         1888 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.250, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000245 DAZUDJ010000000
VERSION     DAZUDJ010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1888
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.250"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1220..1822
                     /gene="fimB"
                     /locus_tag="ACHY1N_005321"
     CDS             1220..1822
                     /gene="fimB"
                     /locus_tag="ACHY1N_005321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimB"
                     /protein_id="HFS4047422.1"
                     /translation="MKNKADNKKRNFLTHSEIESLLKAANTGPHAARNYCLTLLCFIH
                     GFRASEICRLRISDIDLKAKCIYIHRLKKGFSTTHPLLNKEVQALKNWLSIRTSYPHA
                     ESEWVFLSRKGNPLSRQQFYHIISTSGGNAGLSLEIHPHMLRHSCGFALANMGIDTRL
                     IQDYLGHRNIRHTVWYTASNAGRFYGIWDRARGRQRHAVL"
BASE COUNT          573 a          336 c          394 g          585 t
ORIGIN      
        1 gaatgttcgt aagctatatc acttactcaa tccattttac ccagagtcat aaaatagaat
       61 gtctgttgat ctcattttca tattcctttc agactgaagt gcgttttcat cacccgatga
      121 gaaagaactg aagtgatgtt tgccatagat tgcgagatgc cctgtctcat tgactatctt
      181 ggtgcacctt tatacctgtt ataccagatc aaaaatcacg caatccatac aacaaaacca
      241 gatttgcaat tcgtgtcaca aaatatgtcg atatttttct aagaagaaga tgccatgtga
      301 agccagacga acacttgcgg aggccttcac aaaccaaaga ttgttgttta attatctgtt
      361 ttataagtaa tttatttaaa gtataaacaa ggaaagattt gcaagttaac tcagtgagcg
      421 tggtgaaaat cagtgtttac ccgccatcag gctgagcata attctcatca tgaaatatgt
      481 ttcctggttt gtggcttgta actggtcact tctgaagtcg atctggagag gcttgttgat
      541 gttggtgttt tcaggatgat gtttcactta gtttgtttgc cgtatcgccc ggcgaatggc
      601 tgtgattgag gaaggtttaa gtcgtagtga ccaaagctat atttaccaac gaatgtagat
      661 gaaaaaatca tctcctgcgt tccccatatc tccaggataa aaatgaatgt aacaatctca
      721 tggcgtaagc tgacgaatca gccaggaata atcgctaggg acctaagaat tagcatgata
      781 atagccacta agaaattact gcgctccatg aaatagccat tttgtggcaa atggagttga
      841 ctaataatgt catatgtgag acggctagtt gaacgaatat taaattttgc tgaatttttt
      901 atgttgattt tacttgttac agaacatatc acatgatata tagataagat tagttgcatt
      961 aatgatgagg gttattatta gattcgtatc cgattgataa atatataaag gtacatagca
     1021 tgcaagagca tggcgtttgt atggcaacgt tattataatt aactgttgct actccattta
     1081 agttcactca gaagaactgg tccacttacg ttagttatta agcaaacgtt cgcttttata
     1141 aacataatca ggataaaaat gttggattat tgctaaccca gcacagctag tgcgcgtctg
     1201 taattataag ggaaaaacga tgaagaataa ggctgataac aaaaaaagga acttcctgac
     1261 ccatagtgaa atcgaatcac tccttaaagc agcaaatacc gggcctcatg cagcacgtaa
     1321 ttattgtctg actttgcttt gttttattca tggtttccgg gcgagtgaaa tttgtcgatt
     1381 gaggatttcg gatattgatc ttaaggcaaa gtgtatatat atccatcgat taaaaaaagg
     1441 cttttcaaca acgcatccgc tattgaacaa agaagttcag gctttaaaaa actggttgag
     1501 tatccgtact tcgtacccgc atgctgagag cgagtgggta tttttatctc gtaagggaaa
     1561 tccgctttct cggcaacagt tttaccatat tatctcgact tccggtggta atgccgggtt
     1621 gtcactggag attcatccgc acatgttacg ccattcgtgt ggttttgctt tggcgaatat
     1681 gggaatagat acgcgactta tccaggatta tcttgggcat cgcaatattc gtcatactgt
     1741 ctggtatacc gccagcaatg cagggcgttt ttacggcatc tgggatagag ccagaggacg
     1801 acagcgtcac gctgttttat agagatagtt gagataccag ggatggtgtt aaaaactaca
     1861 ttattcttat gatatatcaa aaatgatt
//
LOCUS       DAZUDJ010000246         1883 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.251, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000246 DAZUDJ010000000
VERSION     DAZUDJ010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1883
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.251"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1883
                     /locus_tag="ACHY1N_005322"
     CDS             <1..>1883
                     /locus_tag="ACHY1N_005322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HFS4047423.1"
                     /translation="AIEAGDECRARAKFHWQFLEHYPAAQDCAYKFIVCEDKPGIPRP
                     ALDSWDAEYMQENRWDEESASFVPVETESYPMNVTFDKLAPEVQNAVMVKFDTCENIT
                     VDMVISAQELLQEDMATFDGHIVEALMKMPEVNTMYPELKLHAIGWVKHKCIPGAKWP
                     EIQAEMRIWKKRREGERKETGKYTSVVDLARARANQQYTENSTGKISPVIAAIHREYK
                     QTWKTLDDELAYALWPGDVDAGNIDGSIHRWAKNEVIDNGREDWKRISASMRKQPDAL
                     RYDRQTIFGLVRERPIDIHKDPVALNKYICEYLTTKGVFENEETDLGTVDVLQSSETQ
                     TDAVETEVSDIPKNETAPEAEPSVEREGPFYFLFTDKDGEKYGRANKLSGLDKALSAG
                     ATEITKEEYFARKNGTYSGSQQNTGASDTTAQPGSVKVTADEVNKIMQAANISQPDAD
                     ELLAVSRGEFVEGISDPNDPKWVKGIQTRDSVNQNQQETEQNDQKAEQNSPNTQQNEP
                     ETKQPEPVVQQEPEKICTACGQSGGGNCPDCGAVMGDATYQEIFDGENQPEVQENDPE
                     EMEGTAHQHKENTGGNQHHASDSETGEASDPLIKANGHHNLTSTSRAGIHLMIDLETM
                     GKNP"
BASE COUNT          578 a          451 c          478 g          376 t
ORIGIN      
        1 gccattgaag ccggtgatga atgtcgcgcc cgcgcaaaat ttcactggca attcctggaa
       61 cattatccgg ctgctcagga ctgcgcttat aaatttattg tctgcgagga taaacctggc
      121 ataccccgcc ctgccctcga ttcatgggat gctgaatata tgcaggaaaa ccgctgggat
      181 gaggagtctg cttcttttgt cccggttgag actgaatcct atccgatgaa cgtcactttt
      241 gacaagctgg cccctgaagt acagaacgct gtcatggtta agttcgacac atgtgaaaac
      301 atcaccgttg atatggtgat tagcgcacag gaattgttgc aggaagacat ggcaacattc
      361 gacggacata tcgttgaagc gttgatgaaa atgccagaag ttaacaccat gtatccggag
      421 cttaagttgc acgccattgg gtgggttaag cataaatgta ttcctggtgc taaatggccc
      481 gaaattcagg cagagatgcg catctggaaa aaacgtcgcg aaggtgaacg caaggaaacc
      541 ggaaaataca cgtctgttgt tgatctcgcc cgcgccagag ccaatcaaca gtacactgaa
      601 aattcaacag gaaaaatcag cccggtcatt gctgccattc atcgcgaata caagcagaca
      661 tggaaaacac tggatgacga actggcctac gctctctggc ctggtgatgt ggatgccgga
      721 aacattgacg gcagcatcca tcgctgggca aaaaatgaag ttatcgacaa cggccgcgaa
      781 gactggaagc gtatctcggc atcaatgcgc aaacagcctg atgcccttcg ctacgaccgc
      841 cagactattt ttggccttgt ccgtgaacgt ccgatcgaca ttcacaaaga tcccgtagca
      901 ctgaacaaat atatctgcga atacctgacg acaaagggcg tgtttgagaa tgaagaaaca
      961 gacctgggca ctgttgatgt tctccagtca tcagaaacac aaactgatgc agtggaaact
     1021 gaggtatctg atatcccaaa aaatgaaacc gcgccggaag ctgaaccatc tgtagagcgt
     1081 gaggggccgt tctacttcct cttcaccgac aaggatggcg aaaaatacgg tcgcgcaaac
     1141 aaactttctg gtctggataa ggcgctgtct gctggggcta ctgaaatcac gaaagaagaa
     1201 tatttcgccc gcaaaaacgg tacatactca ggttcacaac aaaatactgg tgcatctgac
     1261 acgaccgcac aaccagggtc agtaaaagtt accgctgacg aagtaaacaa aattatgcag
     1321 gcagccaata tcagccagcc tgacgccgat gaactgcttg cagtatcacg tggtgaattt
     1381 gttgaaggga ttagcgaccc gaatgatccg aaatgggtta aggggatcca gacccgcgat
     1441 tctgtgaacc agaaccagca agaaacggaa cagaacgacc agaaagcgga acaaaacagc
     1501 ccaaatacgc aacaaaacga gccagaaacg aaacaacctg aaccagtagt gcaacaggaa
     1561 ccggaaaaga tctgcaccgc ctgcggtcag agcggtggcg gcaactgccc tgattgtggt
     1621 gcggtgatgg gtgacgcaac ataccaggaa atattcgatg gagagaatca gcctgaagtt
     1681 caggaaaatg atccggagga aatggaaggc actgcgcatc agcacaagga gaacactggc
     1741 ggcaatcagc atcatgccag cgatagtgaa actggcgagg cgtcagatcc cttaattaag
     1801 gcgaacggtc atcataatct cacatccacc agcagagcgg ggattcatct gatgatcgac
     1861 cttgaaacca tgggaaaaaa tcc
//
LOCUS       DAZUDJ010000247         1857 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.252, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000247 DAZUDJ010000000
VERSION     DAZUDJ010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1857
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.252"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..597
                     /locus_tag="ACHY1N_005323"
     CDS             <1..597
                     /locus_tag="ACHY1N_005323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001365916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4047424.1"
                     /translation="ADGKSITPDDVRPMLEQMVKEAVSHIPAPRDGRDYDPEVLKQAV
                     LEAVNALPAPQDGRDATALEVLPAIDDQKSFPRGTYATHLGGLWRAYEKTHGMRGWEC
                     LVDGVADIDVSMTDERLFSVVIRQSSGQCTEKTFSLPVMLYRGVFRAGETYHPGDTVT
                     WGGSLWHCNSMTGDKPGEAHSSGWTLAAKRGRDAGGGK"
     gene            594..920
                     /locus_tag="ACHY1N_005324"
     CDS             594..920
                     /locus_tag="ACHY1N_005324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFS4047425.1"
                     /translation="MTALLTLEEIKAHLRVDHDADDDMLMDKVRQATAVLLAYIQGSR
                     DKVIREDGELIPGEALTRMKGAAMRLTGMLYRNPDLAEREDLVQGELPFSVSVLIYDL
                     RCPTVL"
     gene            931..1281
                     /locus_tag="ACHY1N_005325"
     CDS             931..1281
                     /locus_tag="ACHY1N_005325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFS4047426.1"
                     /translation="MAISAGRLTQMISVLNPVLTRNAAGEMTEEWVSCGKIHADIRGR
                     SSRERMQSGAEMAQAEIRIWVRGQSGREITAASRLHVLSGPWRDRILNVVGLPVPDAT
                     GGRLEILCRLGGEK"
     gene            1278..1724
                     /locus_tag="ACHY1N_005326"
     CDS             1278..1724
                     /locus_tag="ACHY1N_005326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFS4047427.1"
                     /translation="MIETLLDFSGLEDISRDLQLLSGAENNRVLREATRAGANVLKEE
                     VVSRAPVRRGKLRRNVVVLSRCSRDGGMESGVHIRGVNPDTGNSDNTMKADNPRNAFY
                     WRFVEMGTVNMPPHPFVRPAFDVRSEQAAQVAIARMNRAIDEVLRR"
     gene            1721..>1857
                     /locus_tag="ACHY1N_005327"
     CDS             1721..>1857
                     /locus_tag="ACHY1N_005327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047428.1"
                     /translation="MTEADLYPHLAHLAGGQVYPYVVPLLDGRPSVALPWVVFSLISS
                     VS"
BASE COUNT          384 a          447 c          641 g          385 t
ORIGIN      
        1 gcggacggca aaagtatcac ccccgatgat gtgcgtccga tgcttgagca gatggtgaaa
       61 gaggccgtaa gccatatccc tgctccgcgt gatggtcgtg attacgatcc ggaagtactg
      121 aagcaggcgg ttctggaggc ggtgaatgcc cttccggctc cgcaggacgg gcgtgatgcc
      181 acggcactgg aagtgctccc cgctattgac gatcaaaaat cctttccccg gggcacgtat
      241 gccacacacc tgggtggact ctggcgggcg tatgaaaaaa cgcacgggat gcggggatgg
      301 gaatgcctgg ttgacggggt ggcggatatc gacgtcagca tgacggatga gcggttgttc
      361 tctgtggtga tccggcagag cagtggccag tgtacggaaa aaacattttc cctgccggtg
      421 atgctctacc gcggtgtgtt cagagccggt gaaacctacc accccggcga tacggtgacg
      481 tgggggggct cgctgtggca ctgcaacagt atgaccggtg ataaacccgg agaagctcat
      541 tcatcaggct ggaccctggc tgcaaaacgt ggacgggatg caggaggcgg aaaatgacgg
      601 cattactgac actggaagag atcaaggcac atctgcgtgt tgaccatgac gcggatgatg
      661 acatgctgat ggacaaggtt cgtcaggcta ccgccgtgct gctggcctac attcagggca
      721 gccgggataa agtgattcgt gaggacggtg agctgatccc gggcgaggca ttaacccgga
      781 tgaagggggc tgccatgcga ctgaccggga tgctgtaccg gaatccggat cttgctgagc
      841 gggaagacct cgtgcagggg gaactgccgt tttctgtgtc cgtgctgatt tacgatttgc
      901 gttgtccgac ggtgttatga ggagggagga atggcaatat ctgcaggtcg tctgacacag
      961 atgataagtg ttctgaaccc ggtgttaacc cgtaatgctg ccggagaaat gacggaagaa
     1021 tgggtgtcat gcgggaaaat tcatgcggat atccgtggca ggagcagccg ggagcggatg
     1081 cagtccggtg cggaaatggc gcaggcggaa atccgcatct gggtgcgcgg tcagtccggc
     1141 cgggaaatca cggcagcgtc acgacttcat gtgctgagtg gtccctggcg tgaccggatc
     1201 ctgaacgttg tcgggctgcc cgtgccggat gcgaccggtg ggcgtctgga aattctctgt
     1261 cggctgggag gggaaaaatg atcgaaaccc tgctggattt ttcggggctg gaggacatca
     1321 gccgcgattt gcagcttctg agtggtgcag aaaataaccg ggtgctgcgt gaggcaaccc
     1381 gtgcgggtgc gaatgtgctg aaagaagaag tggtgtcacg ggcaccggta cgcaggggaa
     1441 aactgcgccg caatgtggtg gtcctttccc ggtgctcccg cgatggcggg atggaatccg
     1501 gtgtccatat ccgtggtgtt aatccggaca ccggtaacag cgataacacc atgaaggcgg
     1561 ataacccgcg caatgctttc tactggcggt ttgtggaaat ggggaccgtg aatatgccac
     1621 cgcacccgtt tgtgcgcccg gcatttgatg tgcgcagtga acaggcggca caggtggcga
     1681 ttgcgcggat gaaccgggcc attgatgagg tactgagacg atgacggagg cggatttgta
     1741 tcctcatctg gcacatcttg ccggcgggca ggtgtacccg tatgtggtcc ccctgctgga
     1801 tggcaggccg tcggtggcgc ttccgtgggt ggttttcagt ctgatttcat cggtgtc
//
LOCUS       DAZUDJ010000248         1853 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.253, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000248 DAZUDJ010000000
VERSION     DAZUDJ010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1853
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.253"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..109
                     /locus_tag="ACHY1N_005328"
     CDS             <1..109
                     /locus_tag="ACHY1N_005328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047429.1"
                     /translation="MQCFYHIINNCEDDSVKSKAQAYIELLNDNSEDNG"
     gene            443..1819
                     /gene="ygeH"
                     /locus_tag="ACHY1N_005329"
     CDS             443..1819
                     /gene="ygeH"
                     /locus_tag="ACHY1N_005329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HilA family transcriptional regulator YgeH"
                     /protein_id="HFS4047430.1"
                     /translation="MDLENKFSYHFLEGLTLTEDGILTQGNEQVYIPQKELGVLIVLL
                     ESAGHVVLKDMIIESVWKNIIVSDESLTRCIYSLRCIFEKIGYDRCIETIYRKGYRFS
                     GQVFKTKINEDNTSDYSIAIFPFTTSLNTLDPLILNQELVQIISNKKIDGLYTYPMAA
                     TNFCNDHISQNSFLSRFKPDYFVTGRINQNNAVNTLYIELIDAKNLFLIASNHLPVDE
                     LHNTSQFIIDNILQTVHKPERSVRLAKQDQGYKNHYLSDEMLAGKKELYDFTLESIYR
                     AMTIFDRLQNKSDIQTLKTECYCLLAECHMSLALHGKSELELAAQKALELLDYVSDIT
                     TVDGKILAIMGLITGLSGQAKVSHILFEQAKIHSTDIASLYYYRALVHFHNEKIEEAR
                     ICIDKSLQLEPRRRKAVVIKECVDMYVPNPLKNNIKLYYKETESESHRVIIDNILKLK
                     QLTRICMR"
BASE COUNT          668 a          309 c          310 g          566 t
ORIGIN      
        1 aatgcaatgt ttctatcaca ttattaacaa ttgtgaggat gatagtgtta agagtaaagc
       61 gcaggcatat attgaactct taaacgataa ttcagaagat aatggctaag cattacaatc
      121 atttggttaa atttgctggt tatagtgcag ttaaccacta taaccagcac ctcttatgtt
      181 ttcttaaatc agcatcttaa aacagttaag agcatactat aaatcattat ttttcaatgc
      241 gttagagaac aatctacttt atcaaaattg aataaggcta tttcagatta catcactgaa
      301 ttcctaagat aaattagtga acacaaccat agaatgtcga atgtaatttc ctgtagcgtt
      361 aatgacacat aaatatgaat agccataatt tctattgctt aagcaggatg caagaaacca
      421 attttttcat agaggttaac taatggactt agaaaataaa ttctcatatc attttcttga
      481 gggattaacg ctcacggaag atggaattct tactcaagga aatgagcaag tttatattcc
      541 acagaaagag ttaggtgtat taatagtatt acttgaatcc gctggtcatg ttgtactgaa
      601 agatatgatc atcgaatcag tatggaaaaa tattattgtt agtgacgagt ccctgacaag
      661 atgtatctat tctttgcgct gcatttttga aaaaattggc tatgatcgtt gcatagaaac
      721 aatctaccgg aaaggttatc gtttcagcgg gcaggttttc aaaactaaaa ttaatgaaga
      781 taatacttca gactattcca tagctatatt ccctttcact acttcgttga atacactgga
      841 tccattaata cttaatcagg aattagtgca aatcatttca aataaaaaaa tcgatggtct
      901 ctatacctat ccgatggctg cgacaaattt ttgtaatgat cacatatctc aaaattcatt
      961 cttgagcaga ttcaagccag attatttcgt tacaggaaga ataaaccaga ataatgcagt
     1021 gaacacttta tacattgagt tgatcgacgc taaaaacctt ttcctcatcg ccagtaatca
     1081 tctccctgtt gatgaactac ataatacatc acaatttatt atagataata tccttcaaac
     1141 ggtacataaa ccagaacgat ctgtaagatt agctaagcag gaccaaggat ataagaatca
     1201 ttatttatca gatgaaatgt tagccggaaa gaaagaactt tacgacttca cccttgaaag
     1261 catttacagg gccatgacta tatttgatag attacaaaat aaaagtgata tacagacgct
     1321 aaaaacagaa tgttattgcc ttctagcgga atgccatatg tctttggcac ttcatggaaa
     1381 aagtgaactt gaacttgctg ctcaaaaagc attagagctt ttagattatg tatcagacat
     1441 aaccactgtc gatggaaaaa ttttagctat tatgggactg ataactggtc tgtctggaca
     1501 agcaaaagta tctcatatct tatttgaaca ggctaagata cactcaactg atatagcctc
     1561 tctctactac tatagggcac tagtccactt tcataatgaa aaaattgaag aggcaaggat
     1621 ttgtatagac aaatcactac aactcgaacc cagaagacga aaagcagttg tgataaaaga
     1681 atgtgtagat atgtatgtgc ctaacccgct caaaaacaac attaaactct actataaaga
     1741 aactgagagt gaaagccatc gagttataat tgacaacatt ttgaaattaa agcagctgac
     1801 gagaatttgt atgcgataaa tttttattga cgcaatttta ttatttagat gta
//
LOCUS       DAZUDJ010000249         1835 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.254, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000249 DAZUDJ010000000
VERSION     DAZUDJ010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1835
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.254"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..628
                     /gene="escR"
                     /locus_tag="ACHY1N_005330"
     CDS             <1..628
                     /gene="escR"
                     /locus_tag="ACHY1N_005330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312610.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type III secretion system LEE export apparatus
                     protein EscR"
                     /protein_id="HFS4047431.1"
                     /translation="QPIFLIIVFFLLSLLPIFVVIGTSFLKISIVLGILKNALGIQQV
                     PPNMALTSVSLILTMFIMSPIILQINDNISQEPINYTDSDFFQKVDEKILSPYRGFLE
                     KNTEKENVEFFERAAQKKLGNETILKKDSLFILLPAFTMGQLEAAFKIGFLLYLPFIA
                     IDLIISNILLALGMMMVSPVTISIPFKILLFILVGGWQKLFEFLLVVN"
     gene            628..897
                     /gene="escS"
                     /locus_tag="ACHY1N_005331"
     CDS             628..897
                     /gene="escS"
                     /locus_tag="ACHY1N_005331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE export apparatus
                     protein EscS"
                     /protein_id="HFS4047432.1"
                     /translation="METGYFVQLCVQTLWIIFILSLPTVIAASVVGIIISLVQAITQL
                     QDQTLPFLLKIIAVFATLALTYHWMGTTIINFSSIIFEMIPKVNG"
     gene            897..1673
                     /gene="escT"
                     /locus_tag="ACHY1N_005332"
     CDS             897..1673
                     /gene="escT"
                     /locus_tag="ACHY1N_005332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE export apparatus
                     protein EscT"
                     /protein_id="HFS4047433.1"
                     /translation="MNEIMTVIVSSFFCILRPLGMFIILPIFSTGVLLSNFIRNSIMI
                     AFTLPIIVENYTFSEKLPSGIFQLTGIVLKEISIGFFIGLSFTILFWAIDAAGQIIDT
                     LRGSTISSIFNPSISDSSSITGVILYQFITVIFVIHGGIQSVLDKLYLSYEILPLQAD
                     IAFNRALVDFLFSLWDSFIKLMLSFSIPMIIGIFLCDMGFGFLNKTAPQLNVFTLSLP
                     VKSLIAIFILLLVIHVFPDFITANIHSDIIDRSLPSMINE"
     gene            1666..>1835
                     /locus_tag="ACHY1N_005333"
     CDS             1666..>1835
                     /locus_tag="ACHY1N_005333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EscU/YscU/HrcU family type III secretion system
                     export apparatus switch protein"
                     /protein_id="HFS4047434.1"
                     /translation="MSEKTEKPTPKKLRDLKKKGDVTKSEEVMAAVQSLILFSFFSLY
                     GASFFVEVVELV"
BASE COUNT          542 a          294 c          326 g          673 t
ORIGIN      
        1 acagccaata tttttaatta ttgtattttt tcttttatca ttactgccta tatttgttgt
       61 tattggtact tcattcctga aaatttcgat tgtattgggg attctgaaga acgcattagg
      121 tattcaacag gtaccaccaa atatggcgct aacatcagta tctttgatac tgacaatgtt
      181 tattatgtct ccgataatat tacagataaa tgataatatt tctcaggaac caatcaatta
      241 caccgactct gatttttttc aaaaagttga tgaaaaaata ttatcaccat accgcggttt
      301 tttagaaaaa aatacagaga aagaaaatgt tgagtttttt gaacgtgcag ctcaaaaaaa
      361 attgggtaat gaaactatct taaaaaaaga ctctctattt atactgttac cagctttcac
      421 gatggggcag cttgaagctg cattcaagat aggttttttg ctctatttac cttttattgc
      481 gatagatttg atcatttcca atatcttatt ggccttgggt atgatgatgg tatcgccagt
      541 aacaatttcg attcctttta agatcttgtt attcattctt gttggaggct ggcaaaaatt
      601 attcgaattt ctgttggtgg tgaattgatg gaaactggat attttgttca attatgtgtg
      661 caaacgcttt ggataatatt tatcctctca ctgcctacag tcatagcggc ctctgttgtc
      721 ggcattatta ttagcctggt tcaggctata acgcagttac aggatcaaac attgcctttt
      781 ttgctaaaaa taatagcagt gtttgctacg cttgccctga cttatcactg gatgggaaca
      841 acaatcatca acttctcgtc gataatattt gaaatgattc cgaaggtgaa tggctaatga
      901 atgaaataat gacggtcata gtatcatcat ttttttgtat actcaggccg ctggggatgt
      961 ttattattct accaatattt tcaacaggtg ttttgctcag taactttata cgcaactcaa
     1021 ttatgattgc gtttacactt ccaattatag tagagaacta tacattttcg gaaaaattac
     1081 catccggaat ttttcagttg acaggcatag tgctaaaaga aataagtata ggctttttca
     1141 ttgggttatc atttactatt cttttttggg caatagatgc ggctgggcag attattgata
     1201 ctttaagagg ttcaacaata tcttcaattt ttaacccgtc tataagtgat tcatcttcta
     1261 tcactggtgt tattttatac caatttatca ctgtgatctt tgttattcat ggtgggatac
     1321 aaagcgttct ggataagttg tatttatcct acgagatatt accattacaa gccgatattg
     1381 cattcaatcg tgctttagta gattttttat tttcgctatg ggattcattt attaaactga
     1441 tgttatcatt ttcaattccc atgattatcg gtatcttctt atgtgatatg gggtttgggt
     1501 ttctcaataa aacagcgcct cagctaaacg tattcacatt atcactgccg gtaaaaagtt
     1561 tgatagcaat ctttatattg ttattagtta ttcatgtttt ccctgatttt attacggcaa
     1621 atattcattc tgacataatt gacagatcgt taccgagcat gattaatgag tgaaaaaaca
     1681 gaaaagccca cacccaaaaa actaagggat ctaaaaaaga agggcgatgt aacaaaaagt
     1741 gaagaggtaa tggctgcagt gcagtcatta atcttatttt catttttttc tttatatggt
     1801 gcgagttttt tcgttgaggt tgttgagtta gttaa
//
LOCUS       DAZUDJ010000250         1729 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.255, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000250 DAZUDJ010000000
VERSION     DAZUDJ010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1729
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.255"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1620
                     /locus_tag="ACHY1N_005334"
     CDS             <1..1620
                     /locus_tag="ACHY1N_005334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HFS4047435.1"
                     /translation="YDRAYGWNDNGDLVRISGPRQTREYGYSATGRLESVRTLAPDLD
                     IRIPYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYHYDEYGRLTEKTDLIPA
                     GVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERDL
                     TGWMSLSRKPEMTWYGWDGDRLTTVQTDTTRIQTVYQPGSFAPLIRIETDNGEREKAQ
                     RRSLAEKLQQEGSEDGHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQ
                     LARQVEPEYTPARKVHFYHCDHRGLPLALISEDGNTAWRGEYDEWGNQLNEENPYYLH
                     QPYRLPGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNYPLNPIIRMDP
                     LGLYNLYQLLYDVWHDDSYGTSSIDITGSGDLISLGGHAGLGVAFAKKKGEMLSDICI
                     YATACGHAGIGGGINAAITYSETKSLPTSGVSNSVGVTVGGGVGGHFAYTYVVDVDNP
                     ESSTESVGIGAGVDASVMTLACRTWQECWVN"
BASE COUNT          423 a          407 c          541 g          358 t
ORIGIN      
        1 tatgaccgtg cctacgggtg gaatgacaac ggcgacctgg tgcgcatcag cggcccgcga
       61 cagacgcggg aatacggcta cagcgccacg ggcaggctgg agagcgtgcg taccctcgca
      121 ccggacctgg acatccgcat cccgtatgcc accgacccgg cgggaaaccg cctgccggac
      181 ccggagctgc acccggacag taccctcacg gcgtggccgg ataaccgcat cgcagaggat
      241 gcgcactatg tttaccacta tgatgaatac ggcagactga cggagaagac ggaccttatc
      301 ccggcgggtg ttatccggac ggacgacgag cggacccacc actaccacta cgacagccag
      361 caccgtctgg tgttctacac gcggatacag catggcgagc cactggtcga gagccgctac
      421 ctctacgacc cgctgggacg gcgaatggcg aaacgggtat ggcggcggga gcgtgacctg
      481 acggggtgga tgtcgctgtc gcgtaaaccg gagatgacgt ggtacgggtg ggacggcgac
      541 cggctgacga cggtacagac cgacaccacg cgtatccaga cggtatatca gccggggagc
      601 ttcgcgccgc tcatccgcat cgaaacagac aacggcgagc gggagaaagc gcagcgccgc
      661 agcctggcgg agaagctgca gcaggaaggg agcgaggacg ggcacggcgt ggtatttccg
      721 gctgaactgg tgcggctgct ggacaggctg gaggaagaaa tccgggcaga ccgcgtgagc
      781 agtgaaagcc gggcgtggct tgcgcagtgc gggctgacgg tggagcaact ggccagacag
      841 gtggagccgg aatacacacc ggcgcgaaaa gttcattttt accactgcga ccaccggggc
      901 ctgccgctgg cgctcatcag cgaagacggc aatacggcgt ggcgcgggga gtatgatgaa
      961 tggggcaacc agcttaatga agagaacccg tattacctgc accagccata ccgtctgccg
     1021 gggcagcagc atgatgagga atcagggctg tactataacc ggaaccggta ctatgacccg
     1081 ctacagggga ggtatattac acaagacccc attgggctgg cggggggatg gaacctgtat
     1141 aattacccac tgaatccgat aataaggatg gatcctttgg gtttgtataa tttatatcaa
     1201 ttattatatg atgtttggca tgatgattca tatggaacat catcaattga tattactggc
     1261 agtggagatc taatatcatt aggtggtcat gcaggacttg gcgttgcgtt tgctaaaaag
     1321 aaaggtgaaa tgttatctga tatttgtatt tatgctacag catgcggaca tgcaggaatt
     1381 ggtggtggga taaatgcggc tatcacatat tctgagacca agtctttacc tacatcggga
     1441 gtcagcaatt cagtaggtgt aacggttggc ggcggagttg gggggcattt tgcgtatact
     1501 tatgtagtgg atgttgataa tccagaatca tcgacagaat ctgttggtat cggtgcaggt
     1561 gttgacgctt cagttatgac tctggcttgt agaacgtggc aagaatgctg ggtcaattaa
     1621 caggaggaaa tatgaaaaaa tatatatttt tagttttatt tttattgtgt ggttgttctc
     1681 cagtggacat agagccagct agacaagaag ttaatatctt tcgtggttt
//
LOCUS       DAZUDJ010000251         1699 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.256, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000251 DAZUDJ010000000
VERSION     DAZUDJ010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1699
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.256"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..301)
                     /gene="grlR"
                     /locus_tag="ACHY1N_005335"
     CDS             complement(<1..301)
                     /gene="grlR"
                     /locus_tag="ACHY1N_005335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE GrlA-binding
                     negative regulator GrlR"
                     /protein_id="HFS4047436.1"
                     /translation="MIMKDGIYSIIFISNEDSCGEGILIKNGNLITGGDIASVYQGVL
                     SEEEDIILHVHRYNHEIPSVLNIEQDYQLVIPKKVLSNDSNVTLHCHVRGNEKLFV"
     gene            498..956
                     /gene="etgA"
                     /locus_tag="ACHY1N_005336"
     CDS             498..956
                     /gene="etgA"
                     /locus_tag="ACHY1N_005336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE muramidase EtgA"
                     /protein_id="HFS4047437.1"
                     /translation="MKKIILSIILISNSCYASDCFEITGKAYNIDPLILKAIAWNESK
                     NKNGIKSKINKNGTYDIGIMQINSSHLDLLSKFNISEDDLLNDACINISVAGYILASN
                     IKSRGNTWDAVGAYNAGYFNTPNAVELRRQYAMKIYKTYTKLKNNEQIID"
     gene            complement(953..>1699)
                     /gene="escU"
                     /locus_tag="ACHY1N_005337"
     CDS             complement(953..>1699)
                     /gene="escU"
                     /locus_tag="ACHY1N_005337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system LEE export apparatus
                     switch protein EscU"
                     /protein_id="HFS4047438.1"
                     /translation="VTTGVSQTGFIFAVEKIKPSAQKISVKNNLKNIFSVKSIFELLK
                     SVFKLVIITLIFYFMGHSYANEFANFTRLNAYQTLVVVAFFVFLLWKGVLFGYLLFSV
                     FDFWFQKHEGLKKMKMSKDEVKREAKDTDGNPEIKGERRRLHSEIQSGSLANNIKKST
                     VIVKNPTHIAICLYYKLGETPLPLVIETGKDAKALQIIKLAELYDIPVIEDIPLARSL
                     YKNIHKGQYITEDFFEPVAQLIRIAIDLDY"
BASE COUNT          581 a          308 c          254 g          556 t
ORIGIN      
        1 caacaaacaa tttttcattt cctcttacat ggcaatgtaa tgtgacatta ctatcattac
       61 tcagtacttt tttagggata actaattgat aatcttgttc aatgtttagc accgagggaa
      121 tttcatgatt atagcgatgg acatgaagta tgatgtcctc ctcttcagac aggaccccct
      181 gatacacaga agcaatatct ccgccagtga tcaaatttcc atttttaatc agtatacctt
      241 ccccacagga atcttcattg ctaataaaga taatgctata gatgccatcc ttcataatca
      301 taactcactc agtttcatac taacctcact cctttcaatt tgttctatcc ataagcgata
      361 tcaagaataa cggagacctt tctttttctc cagattgcaa tgtaatatat cattaaatat
      421 actcatattc caacctgttg ttttccgtgg ttgacatatt taatttctga tgaatcatat
      481 tgaatatcaa catgaaaatg aaaaaaatta tattgagtat cattctcatt tcaaattctt
      541 gttatgcttc tgattgtttt gaaattactg gaaaagcata taatatagac ccattaatat
      601 taaaggcaat tgcatggaac gaatcaaaaa acaaaaacgg aataaaaagt aaaataaaca
      661 aaaacggaac gtatgatata ggtataatgc aaataaattc atctcattta gatttattaa
      721 gcaaatttaa tatatctgaa gatgatttat tgaatgatgc ctgtataaac atatctgttg
      781 ctggttatat cttagcctct aacataaaat ccagggggaa tacatgggat gcagttggtg
      841 cgtataatgc aggctacttt aacacaccaa atgcagtaga actcagaaga caatatgcaa
      901 tgaaaatata taaaacatac actaaattaa aaaacaatga acaaattatc gattaataat
      961 caagatctat tgctatacga atcaattgtg ctacaggttc aaaaaagtct tctgttatgt
     1021 attgtccttt atgtatgttc ttataaagac ttcttgccaa aggaatatct tcaatcactg
     1081 gaatatcata gagttcagcc agtttaatga tctgtagagc tttggcatct tttcctgttt
     1141 caataactaa aggcaatgga gtctccccga gtttatagta taggcaaatc gcaatgtgag
     1201 tcgggttttt gacgatcacg gttgattttt tgatgttatt agccagactt ccactttgta
     1261 tctcagaatg aaggcgacgg cgctcccctt taatttcagg gttaccatca gtatccttgg
     1321 cttctcgttt cacctcatct ttactcattt tcattttctt cagtccctca tgcttctgga
     1381 accagaaatc aaatactgaa aagagtagat atccgaataa cacgcctttc cataaaagaa
     1441 aaacaaaaaa ggcaacaacg acaagagttt gatatgcgtt cagtcttgtg aaatttgcaa
     1501 actcatttgc atatgaatgc cccataaagt aaaaaatgag agtaattatc actaacttaa
     1561 atactgactt aagcagctca aaaatactct ttacagaaaa aatatttttc aggttatttt
     1621 ttacactaat cttctgagcc gatggtttta ttttttcaac cgcaaagatg aatcctgttt
     1681 gtgatacacc agttgtaac
//
LOCUS       DAZUDJ010000252         1685 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.257, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000252 DAZUDJ010000000
VERSION     DAZUDJ010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.257"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1027
                     /locus_tag="ACHY1N_005338"
     CDS             <1..1027
                     /locus_tag="ACHY1N_005338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047439.1"
                     /translation="WLDRQASSWDDAIIYENVESFWSRVNTQNALPKNYIIGTPLILP
                     TSKNESIEKIHIFFMWKDILSLIADHHNSDCSVLFFTNEDKSYTVELTHFLQYSEINR
                     LSNSSLKYEIIKELLDTIKINDLHKSERKLVIRSAINEVFKANGTFNFFDLLNSTELV
                     RKKYDELYEIYTKRFSVNKILNELDEKNLEFTSKINEFISSNQTKALTIPGALIAAGG
                     LVKANETTEAILIIAGLWMIKKVNYISIEIFNETFDNLRSRVESAFDKYLKFEENKEI
                     KDNADSIKSSITGLIDKAKKRMRTVKYLASAMFYGGLIYVGYKQFPVFFEKSAVNLFY
                     FLCHTIS"
     gene            complement(1007..1363)
                     /locus_tag="ACHY1N_005339"
     CDS             complement(1007..1363)
                     /locus_tag="ACHY1N_005339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0060567 - negative regulation of
                     termination of DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator Q family protein"
                     /protein_id="HFS4047440.1"
                     /translation="MRDMYEVMDRWGAWAASDNSGVDWQPIAAGFKGLLPHGKKSRIQ
                     CDDDEGIMIDSCVARLRRYKPEEYELIIAHFVIGISLRTIAKKRKCSDGTIRKELQTA
                     MGFVDGCLAMLAYSMA"
     gene            complement(1381..1581)
                     /locus_tag="ACHY1N_005340"
                     /pseudo
     CDS             complement(1381..1581)
                     /locus_tag="ACHY1N_005340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416078.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
BASE COUNT          543 a          366 c          299 g          477 t
ORIGIN      
        1 ttggctagat cgccaagctt catcttggga tgacgctata atttatgaga atgttgagtc
       61 tttttggtct agagtaaaca cccaaaacgc tcttccgaaa aattatatca tcggaacgcc
      121 gttaatactc cctacttcta agaatgaaag catcgaaaaa atccatattt tctttatgtg
      181 gaaagatatc ctttcattaa ttgctgatca tcataacagt gactgctctg tcttattttt
      241 caccaatgaa gacaaaagtt atacagtcga actcacgcat tttttacaat atagcgagat
      301 taatcgctta tcgaactcgt ctcttaaata tgaaattata aaggagcttc tcgacacaat
      361 aaaaatcaat gatttacaca aaagcgagcg caagctcgtt atacgctcag ccataaacga
      421 agtatttaaa gcaaatggta cgttcaattt ctttgacttg cttaactcta ctgaactcgt
      481 caggaaaaaa tatgatgaac tatatgagat ttacacaaag aggttttctg taaataaaat
      541 tcttaacgaa ctcgatgaga aaaatcttga gttcacgagt aaaattaacg aattcatatc
      601 atctaatcag acaaaagcat tgactattcc cggtgcatta atagctgctg gtggcttagt
      661 gaaggctaat gaaacaaccg aagcaatatt gattatcgca ggactttgga tgataaaaaa
      721 agtcaattac atttctattg agatattcaa tgaaacattc gacaacttac gttctcgagt
      781 ggagtccgct ttcgataagt atttaaagtt tgaagaaaat aaagaaatca aagataatgc
      841 agatagtatt aagagtagca ttacaggttt gattgataaa gctaaaaaaa ggatgagaac
      901 tgttaaatat ctcgcatcag ccatgtttta tggaggcctt atttacgttg gatataaaca
      961 gttcccagtc ttttttgaaa aatcggcagt aaatctattt tattttttat gccatactat
     1021 aagctaacat tgctaaacag ccgtcaacaa accccattgc agtttgcagt tccttcctaa
     1081 ttgtgccatc agagcatttt ctcttcttcg caatagtgcg taatgagata ccgataacaa
     1141 agtgggcgat gatgagctca tattcctctg gtttatacct tctcaaccga gccacacaac
     1201 tgtctatcat gatgccttcg tcatcatcac actgaatccg tgactttttg ccatgaggta
     1261 aaagtccctt gaaaccagcc gctatcggct gccagtccac tccgctattg tctgaagcag
     1321 cccaagctcc ccaacgatcc attacttcat acatatcacg catcaacttt ctccacaaaa
     1381 tcaggccagc acaccaattg ccagcgcacg atcgataaaa cgaaatatca actccagctg
     1441 ggagccatac ttctcttcaa atgccacggt atccgcatgc agctcgtcgt gatgctttct
     1501 gcacaaaggc aacacaaaga gatcatgcgc ttttgtaccc attcccccct gaccgtggcc
     1561 tatcagatgg tggggatcat cagtgaaccg ccccgggaat cctggagact aaactccctg
     1621 agaaagaggt aaacaggatg actaaaaata cacgtttttc ccccgaggtc cgtcaacggg
     1681 cagtt
//
LOCUS       DAZUDJ010000253         1683 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.258, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000253 DAZUDJ010000000
VERSION     DAZUDJ010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1683
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.258"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..108
                     /locus_tag="ACHY1N_005341"
     CDS             <1..108
                     /locus_tag="ACHY1N_005341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HFS4047441.1"
                     /translation="TDIRKDRCSKCMRGCEMRGMVANFGGFLSINKLSQ"
     gene            119..862
                     /locus_tag="ACHY1N_005342"
     CDS             119..862
                     /locus_tag="ACHY1N_005342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309144.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFS4047442.1"
                     /translation="MTQTESAILAHARRCVPAESCGFVVRTPEGERYIPCVNISAEPE
                     AYFRIAPEDWLRAEMQGEIVALVHSHPGGLPWLSEADRRLQIKSALSWWLVCRGDIHK
                     FRCVPHLTGRLFEHGVTDCYTLFRDAYHLAGIDMPDFEREDDWWRNGQNLYLDNMAVT
                     GFYRVPLSSAQAGDILLCCFGASVANHAAIYCGNGELLHHLPEQLSKRERYSEKWQRR
                     THSAWRHRHWHASAFTGICNDLAAASACM"
     gene            859..1440
                     /locus_tag="ACHY1N_005343"
     CDS             859..1440
                     /locus_tag="ACHY1N_005343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309145.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HFS4047443.1"
                     /translation="MNTAAEAIRALSLQVPGFRRQMNEGWYQIRIRGEDTAPEAVYAR
                     LHEQLGEGAVIHIVPRLAGAGKGGLQIVLGAAAIVGSFFTAGASMALWGSALAAGGFS
                     ATTMLFSLGASMILGGVAQMLAPKPKTPEYRATDNGRQNTYFSSLDNMIAQGNPMPVP
                     YGEMLVGSRRISQDISTRDEGGDGKMVVIGRQA"
BASE COUNT          366 a          408 c          534 g          375 t
ORIGIN      
        1 acggatatcc gtaaggacag atgcagcaag tgcatgcgcg ggtgtgagat gcgcggcatg
       61 gtggctaatt ttggcggttt cctttccatt aataaacttt cgcagtaaat cccggtttat
      121 gacacagact gaatcagcga ttctggcgca tgcccggcgg tgtgtgcctg cggagtcgtg
      181 tggcttcgtg gtgagaacgc cggaggggga gcggtatatc ccttgtgtga atatctctgc
      241 agagccggag gcgtattttc gtattgcacc ggaagactgg ctgcgggcag agatgcaggg
      301 ggagattgtg gcactggtcc acagtcatcc cggtggtctg ccctggctga gcgaggccga
      361 ccggcggctg cagataaaaa gtgcactgtc ctggtggctg gtctgccggg gggacattca
      421 taaattccgc tgtgtgccac atctgacagg acggctcttt gagcacgggg tgacggactg
      481 ttacacgctg ttccgggatg cctaccatct ggcgggaatt gatatgccgg attttgagcg
      541 tgaggatgac tggtggcgta acggtcagaa cctttacctg gacaatatgg cggtcaccgg
      601 cttttaccgg gtgcccctgt cctctgcaca ggcgggcgat atcctgctgt gctgctttgg
      661 cgcatcggtg gccaatcatg ccgccatata ctgcggcaac ggtgagctgc ttcaccatct
      721 gcctgaacaa ctgagtaaac gggagaggta ttccgaaaaa tggcaacgac gaacgcattc
      781 agcctggcgt caccgccact ggcacgcatc tgccttcacg gggatttgca acgatttggc
      841 cgccgcctca gcctgtatgt gaacacggca gcggaagcca tccgggcgct gtcgttacag
      901 gtgccgggat tccgccgtca gatgaacgaa ggctggtacc agatacgtat tcgcggtgag
      961 gacacggcac cggaggcggt gtacgcccgt cttcacgaac agctgggtga gggggcggtc
     1021 atccatattg tgccgcgact ggccggggcc ggaaagggtg gactgcagat tgtgctgggg
     1081 gcggcagcca tcgtgggctc tttcttcact gccggggcat caatggcgtt atggggttca
     1141 gccctggcag ccggtggttt ttctgccacc acgatgctgt tttcactggg ggccagcatg
     1201 atactgggtg gtgtggcaca gatgcttgcc ccgaagccaa aaacaccgga atacagggca
     1261 acggataacg gcagacagaa cacgtacttt tcctcgctgg ataacatgat tgcccagggg
     1321 aacccgatgc cggtgcctta cggtgaaatg ctggttggct cccggcgaat ctcccaggac
     1381 atcagtaccc gtgatgaagg cggtgacggg aagatggtgg ttatcgggcg gcaggcataa
     1441 aagcgaaaaa atcccgcagt gctcacggac aggaactgcg ggagcgttac gaagattgag
     1501 tgtaaggaat tattcttatg tcacgacaaa aaacattaac gcagagaaat tattagcgcc
     1561 acagtcagtt tgtgaaaatg tgaagatatt cagaattttt attcagtcat gatacaggca
     1621 tcctccggga tgcctgttgt ttttgtgcgt aacagttatc acagtaaagg gtgagacaat
     1681 ggg
//
LOCUS       DAZUDJ010000254         1665 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.259, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000254 DAZUDJ010000000
VERSION     DAZUDJ010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1665
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.259"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            83..958
                     /locus_tag="ACHY1N_005344"
     CDS             83..958
                     /locus_tag="ACHY1N_005344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein EspS"
                     /protein_id="HFS4047444.1"
                     /translation="MFSIRSQLPISASVSIPAEQSQSISTIPGGRKIETVPEKEGLLV
                     FLGTKSVGEYALNILGQNVSRVTTGKKPYDILFLHEATKQDFDKKKTEFTFPGANRSY
                     LQSSNTDVAAAAAISIAATEMKTILPKDLTPEKYNKIYLPGDGSAGLPLLKCGDEFLS
                     PTDIVNRLVEHNLHEVEDIRLTSCHSANITKNNDFSPEEIEKSTKTNSGWLASALFGQ
                     KRSLAEHVYAEFEGRGINVSVSGYHGTGVFYVPEHGKPTTHLRSTTVPATPEQTVRRS
                     DYRVSLGRTQPTDID"
     gene            complement(1198..1371)
                     /locus_tag="ACHY1N_005345"
                     /pseudo
     CDS             complement(1198..1371)
                     /locus_tag="ACHY1N_005345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313136.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT          533 a          382 c          301 g          449 t
ORIGIN      
        1 tcagctatta tcaactaaaa tattactcac tccattagaa ttatcatgaa ctcacattta
       61 aacaaactaa gaaggaggtt gtatgtttag tataagatcc cagctaccta taagcgccag
      121 cgtatcaatt ccggcagaac aatctcaatc catctccaca attcctggag ggagaaaaat
      181 agagacagtg ccagagaaag aaggattgct tgtgttttta ggaacaaaat ccgtaggtga
      241 atatgctctt aatattcttg gtcaaaatgt ttcaagagtc acaacaggga aaaaacctta
      301 tgatatatta ttcctgcacg aagctacaaa acaagatttt gataaaaaga aaacagagtt
      361 tacctttcct ggtgcaaaca gaagttatct acaatcaagt aacaccgatg ttgctgccgc
      421 agcagctata agtattgcgg caacagagat gaaaactatc ctaccaaagg atttaacacc
      481 agaaaaatac aataaaattt atctgccagg ggatggttct gctggcctac ctcttcttaa
      541 gtgtggagat gaatttttat caccaactga tatcgtcaat cgtctggtag aacataatct
      601 tcatgaagta gaagacatca gattaacatc ctgtcactca gccaacataa caaaaaacaa
      661 tgatttctct cctgaagaaa tagaaaaatc aacaaaaacc aacagcggct ggttggctag
      721 tgcattattt ggtcaaaagc gttcattagc agaacacgtc tatgccgagt ttgaaggccg
      781 tggaattaac gtttctgtat ccggttatca tggcactggt gttttttatg ttccagagca
      841 tggcaaacca acaacgcatc tacgctccac aacagtgcct gcaacacctg aacagacggt
      901 aagaagaagt gactacagag tctcccttgg cagaactcaa cccacagata ttgactaatt
      961 gagtctgcat ataggtttgt gtcattacct gatgcgctac gcttatcaga cctatattag
     1021 atcctgcaat atgtttaatt tgtaggcaga atagagcgtt cacaccacat caggtataaa
     1081 caaagtacag cttgccaaaa acctgaataa ccccgaattt acggggttat tccgcttaaa
     1141 catgcccata acatcacttc tgatttgtat tgcttacgac ggatacaatt tctctgctca
     1201 gctacgaata tcatcatact cgcgcgtttt atcgaactcg tgtttcgcaa acggacatag
     1261 cgggataatc ttccgcttct cccggcgcat tttttccacc accttcgcca ccagccgttt
     1321 accaatcccc tgccctttca ggctttcatc aacatcggta tgttcgataa tggtcagtta
     1381 tcagggataa ccctgtgagt acaacgcaat ctgttgctac tgggtagact ggtctgctga
     1441 tcacactcac agatttattt cacatatatg aactcatgta tttgatctct ctcttatata
     1501 tttaatacca atcagacagt cttatcccac cagtgatacc tgtccctgcc cacaaggcac
     1561 gggctgcccc tgtagtggca cactaaattt ggccacctga tgaaaggtga tattctcacc
     1621 acaacacaaa acaggtgact taatgaacaa gaaaaccaaa cgaac
//
LOCUS       DAZUDJ010000255         1663 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.260, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000255 DAZUDJ010000000
VERSION     DAZUDJ010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1663
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.260"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(1..1663)
                     /locus_tag="ACHY1N_005346"
                     /pseudo
     CDS             complement(1..1663)
                     /locus_tag="ACHY1N_005346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309571.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
BASE COUNT          345 a          524 c          392 g          402 t
ORIGIN      
        1 cttttaccgt ccgccggtac cggtattttc ccgaccgcat cattcaccgc ctgctgcagt
       61 acatccggat catagtcacg accatcacgc ggaacaggga tatggcttgc tgcgtccttc
      121 accatctgct caagcatcgg acgcacatca tcacccgtca cgcacttctg taataccaca
      181 gactgagaag ccagtttttc ttcaaacgtt tgtgcctgcg cggctatttt ctcctcaaat
      241 gtacgctgta aatccgccag caccatggcg aattcttcgc ccagtgcacg aataatggac
      301 agttcccgtt ccgtcatttt cgcagtatcc ccctgaacat cgctttcacc gcatcatgct
      361 ctgtttcact gattgcctta ttaccgtcag atgcgccatc aggcagttgt gctgagactg
      421 ttttcccgga cgacgcgaac ggatcctcac gggcatcacg acgggacagc gcctccagac
      481 tgtagttctg ctgctgaaga tacagtgcat cacctcccgc aaggggcggc aggttctcac
      541 gtttacgggc ctcattgggc gtcagcagcg tatttttcac cgactcaccc agcgttttca
      601 tgcgccgttc gctgtccatt ctcagcagcg tggtgacgtc aaactccgta ctctcgtttt
      661 cccccgtttc cagcgcctca tccagtaaca gctcaatgga ctcaatcagc gtctgcagac
      721 actgggaata atactgctgc tccagcgcct ccacgttatc actggaggga ggttgtccca
      781 caccaatctt gtaggccggg acacggaaca ccgaacagac aatttcagcc gtcattttca
      841 gttgttccac cgtctgcgca tccaccggtg aaaacgtcgt ggggttatat ttcgccccgt
      901 tgctcagaat cgccgttttc cccgcatttt cgccggtata cccgctgtcc cagttgctct
      961 tcagtttttt cgcattttct tccgtaatac tgccggggat ctcaatcacc ccggacggcc
     1021 tgccgccatt tctgaaaaaa gacgttgaat ttgcctgaat atgatgcccc tgcgtggcag
     1081 ccagcccggc agcatacacc ggcggcagcc ccacaagcgg atgaaaaaaa cagttaaacc
     1141 ggtcgtggat cacttcccgg gcaggcaccg tcaccgcctc cgtgatcccg cagttccggt
     1201 ccggcgtgat gcgatagaac acctcgccgt catccgccac cagaggttca acccggctcc
     1261 agtccagaat acgcagttct ttgatctgcc cacgggagtt acggattttc agcaccaccg
     1321 tattgccgtg acgcagtttg gcgttcagcc acagttcaaa aaactggata cgattctgct
     1381 gtgcattggg acgacgacag agacgggcaa tatccccctg ccgtttttca cggcggatcc
     1441 cctgtgtatc ggtctgcatc aggcgcagtc gcattttggc gatatcctgg gatatcagcg
     1501 aaatgcaaga aaacaccgca tgaaaggaga ggacactttc cggatcggct ttcacgccct
     1561 gctgccaggc gccggcaaaa ggctcagcca ccgcctgaaa caggctggtc cagcccacct
     1621 cttttacatc acgtcctgat ttctggtttt ttcgggttcg ccg
//
LOCUS       DAZUDJ010000256         1661 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.261, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000256 DAZUDJ010000000
VERSION     DAZUDJ010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1661
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.261"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..374)
                     /locus_tag="ACHY1N_005347"
     CDS             complement(<1..374)
                     /locus_tag="ACHY1N_005347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4047445.1"
                     /translation="MATLRELIIKISANSQSFQSELQRASRMGSEYYRTLQNGGRQAA
                     AAAREQRRALAELNSQLTEIRGSAVGMAGAFAGAFATGHLISLADEWSSVNARLKQAS
                     QSSDEFSSSQKVLMDISQRTGTA"
     gene            complement(425..634)
                     /locus_tag="ACHY1N_005348"
     CDS             complement(425..634)
                     /locus_tag="ACHY1N_005348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4035 domain-containing protein"
                     /protein_id="HFS4047446.1"
                     /translation="MWMEFDRVSPLGDERGDIRNAQIVKAVFGAQGMNVSLEDAMLCW
                     GEDEDKVESDPFAALEDALSFAAMS"
     gene            complement(730..1104)
                     /locus_tag="ACHY1N_005349"
     CDS             complement(730..1104)
                     /locus_tag="ACHY1N_005349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HFS4047447.1"
                     /translation="MKKDLKTLALARLSGFRHKTVKVPEWGNVSVVLREPSAEAWYLW
                     QEVLNGDGEDDDTLSVVAKTRRNLEADVTLFCDVLFDTDLQRVFTPDDREQVLAVYGP
                     VHARLLRQALELIADAESARKK"
     gene            complement(1119..>1661)
                     /locus_tag="ACHY1N_005350"
     CDS             complement(1119..>1661)
                     /locus_tag="ACHY1N_005350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major tail subunit"
                     /protein_id="HFS4047448.1"
                     /translation="EQENINGLGASSEISMSGNFYLNQAQNALRDAYDNDALYAFKVL
                     FPSGKGFKFLAEVRQHTWSSGTNGVVAATFSLRMKGKPVSFVVPLAFVKNLDKTLTVN
                     TGALLTMSVSANGGTPPYKYAWKKDGQPVDGQTTDTFSKPGAQSADAGKYTCVVTDSA
                     EKAQSVTSVECTVTVSAAAG"
BASE COUNT          365 a          542 c          387 g          367 t
ORIGIN      
        1 gcggtacctg tccgctggct gatatccatc agcactttct gtgatgacga aaattcatca
       61 gatgactgcg acgcctgttt cagacgggca ttcacggaac tccactcatc agccagtgaa
      121 atcaggtgtc cggtggcaaa ggcaccggca aatgcgccag ccattccgac agcagaaccg
      181 cgaatttccg tcaactggct gttcagttct gccagggcac gtcgctgctc ccgggctgcc
      241 gcagcggcct gacgcccgcc attctgcagg gtccggtaat attcactgcc catacgggaa
      301 gcacgctgga gctccgactg gaatgactgt gaatttgccg aaattttgat aatcagttca
      361 cgtaacgtcg ccattcacct ttctccgggc aaaaaaacct gccacagcag gttttcatca
      421 ttatttatga cattgctgca aagctcagcg cgtcttccag cgccgcaaac ggatctgact
      481 ccactttatc ctcatcctcg ccccagcaga gcatggcgtc ctccagtgaa acattcatcc
      541 cctgcgcccc gaaaaccgct ttcacgatct gcgcattacg gatatccccg cgctcatcgc
      601 ccagcgggga caccctgtcg aactccatcc acatcatcgc ctcgctcgca ctcagactgt
      661 ggcccagttc ggataaggtg cgccccagac ggagcgcaag tcgcatcaga aagagaattt
      721 ccgggcgggc tacttttttc tggccgactc tgcatcagcg atcagttcca gtgcctgacg
      781 cagcaaccgg gcatgtaccg gaccatagac ggccagcacc tgctcacggt cgtccggagt
      841 gaacacccgc tgcagatccg tatcaaacag gacatcgcag aacagcgtca catccgcttc
      901 caggttacgg cgggttttcg ccaccaccga cagggtatcg tcatcctctc catcaccatt
      961 gagcacttcc tgccacagat accaggcctc tgccgaaggc tcccgcagca ccacgctgac
     1021 attaccccat tccggcacct tcaccgtttt atgacgaaac cctgacagtc tggccagcgc
     1081 cagcgttttc agatcctttt tcatgatgac ccatcccctt atccggcggc tgcgctcact
     1141 gtcacggtgc attcaacaga cgtcacactc tgtgctttct ctgccgaatc ggtcaccacg
     1201 caggtatatt tccccgcatc agcggactgc gcacctggct tactgaaggt gtctgtcgtc
     1261 tgcccgtcaa ccggctgacc atccttcttc caggcgtatt tatacggcgg cgttcccccg
     1321 ttggcactga ctgacattgt cagcagcgca cctgtattca cggtaagtgt tttatccaga
     1381 tttttcacaa acgccagcgg taccacaaag gacaccggtt tgcctttcat acgcagtgaa
     1441 aacgttgctg ccaccacgcc gttggtaccg gatgaccagg tgtgctgacg cacttccgcc
     1501 aggaacttaa agcccttacc ggacggaaac agcaccttaa acgcatacaa cgcgtcattg
     1561 tcataggcat cacgcagggc gttctgggcc tgattcagat aaaaattacc cgacatggaa
     1621 atctcagacg acgcccccag accgttgatg ttctcctgct c
//
LOCUS       DAZUDJ010000257         1649 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.262, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000257 DAZUDJ010000000
VERSION     DAZUDJ010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1649
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.262"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..374)
                     /locus_tag="ACHY1N_005351"
     CDS             complement(<1..374)
                     /locus_tag="ACHY1N_005351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4047449.1"
                     /translation="MATLRELIIKISANSQSFQSEIQRASRMGSEYYRTLQNGGRQAA
                     AAAREQRRALAELNSQLTEIRASAVGMTGAFAGAFATGHLISLADEWSSVNARLKQAS
                     QSSDEFSSSQKVLMDISQRTGTA"
     gene            complement(422..631)
                     /locus_tag="ACHY1N_005352"
     CDS             complement(422..631)
                     /locus_tag="ACHY1N_005352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4035 domain-containing protein"
                     /protein_id="HFS4047450.1"
                     /translation="MWMEFDRVSPLGDERGDIRNAQIVKAVFGAQGMNVALKDAMLCW
                     GEDEDKPEVDPFAALEDALSFAAQS"
     gene            complement(727..1101)
                     /locus_tag="ACHY1N_005353"
     CDS             complement(727..1101)
                     /locus_tag="ACHY1N_005353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HFS4047451.1"
                     /translation="MAKDLKTLALARLSGFRHKMVKVPEWRNVSVVLREPSAEAWYLW
                     QEVLNGDGEDDDTLSVVAKTRRNLEADVTLFCDVLCDTDLQRVFTPDDREQVLAVYGP
                     VHARLLRQALELIADAESARKK"
     gene            complement(1107..>1649)
                     /locus_tag="ACHY1N_005354"
     CDS             complement(1107..>1649)
                     /locus_tag="ACHY1N_005354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major tail subunit"
                     /protein_id="HFS4047452.1"
                     /translation="EQENINGLGASSEISMSGNFYLNQAQNALRDAYDNDTVYAFKVQ
                     FPSGKGFKFLAEVRQHTWSSGTNGVVAATFSLRLKGKPVSYVVPLAFVKNPEKTLTVN
                     TGALLTMSVSVNGGTPPYKHAWKKDGQPVEGQTTDTFSKANAQSGDKGAYTCEVTDSA
                     EQPQSITSDACTVTVNGAGG"
BASE COUNT          353 a          538 c          391 g          367 t
ORIGIN      
        1 gccgtgcctg tccgctgact gatatccatc agcactttct gtgatgacga aaattcatcg
       61 gatgactgtg atgcctgttt cagacgggca ttcacggaac tccactcatc cgccagagaa
      121 atcaggtgtc cggtggcaaa ggcaccggca aacgcaccgg tcattccgac agccgaagcg
      181 cggatttccg tcaactggct gttcagttct gccagggcac gtcgctgctc ccgggctgcc
      241 gcagcggcct gacgcccgcc attctgcagg gtccggtaat attcactgcc catacgggaa
      301 gcccgctgga tctccgactg gaatgactgc gaatttgccg aaattttgat aatcagttca
      361 cgtaacgtcg ccattcacct ttctccgggc gtaaaaaaac cgcctcagcg gttctcatca
      421 ttcatgactg tgctgcgaag ctcagcgcgt cttccagcgc cgcaaacgga tccacctccg
      481 gcttatcctc atcctcgccc cagcagagca tggcgtcctt cagtgcaaca ttcatcccct
      541 gtgccccgaa aaccgctttc acgatctgtg cattacggat atccccgcgc tcatcaccca
      601 gcggggacac cctgtcaaac tccatccaca tcatcgcctc gctcgcactc aggctgtgcc
      661 gcagttcgga taaggtgcgc cccagacgga gcgcaagtcg catcagaaag cgaatttccg
      721 ggcgggctac ttttttctgg ccgactctgc atcagcgatc agttccagtg cctgacgcag
      781 caaccgggca tgtaccggac catagacggc cagcacctgc tcacggtcgt ccggagtgaa
      841 cacccgttgc aggtcagtat cacacaggac atcgcagaac agcgtcacat ccgcttccag
      901 gttacggcgg gttttcgcca ccaccgacag ggtatcgtca tcctctccat caccattgag
      961 cacttcctgc cacagatacc aggcctctgc cgaaggctcc cgcagcacca cgctgacatt
     1021 tctccattcc ggcaccttca ccattttatg acggaacccc gacagtctgg ccagcgccag
     1081 tgttttcaga tcttttgcca taagccttat ccgcccgcac cattaaccgt taccgtacac
     1141 gcatcagagg taatgctctg cggctgttct gcagaatccg ttacctcgca ggtataagcc
     1201 cccttatcac ctgactgcgc attggcttta ctgaaagtgt cagtagtctg tccctctacc
     1261 ggctgaccat ccttcttcca ggcgtgttta taaggcggcg ttcccccgtt gacactgact
     1321 gacattgtca gcagcgcacc ggtattcacg gtaagtgtct tctccggatt tttcacaaac
     1381 gccagcggta ccacatagga caccggttta cccttcaggc gaagtgagaa cgttgcagcc
     1441 accacgccgt tggtaccgga tgaccaggtg tgctgacgca cttccgccag gaacttaaag
     1501 cccttaccgg acggaaactg caccttaaac gcatacaccg tgtcattgtc ataggcatca
     1561 cgcagggcgt tctgggcctg attcagataa aaattacccg acatggaaat ctcggacgac
     1621 gcccccagac cgttgatgtt ctcctgctc
//
LOCUS       DAZUDJ010000258         1622 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.263, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000258 DAZUDJ010000000
VERSION     DAZUDJ010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.263"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..891
                     /locus_tag="ACHY1N_005355"
     CDS             <1..891
                     /locus_tag="ACHY1N_005355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein SepQ"
                     /protein_id="HFS4047453.1"
                     /translation="MKINDFYLPLLSVIGTGRLYITPEGHACHAYFREVSGNGIRFTL
                     TCSGYEGRFWISEEQFIQWCQELFPYSESRLIPEDMIKLMILWVMQTALPEGDVSVDD
                     VQFTMLNKDVYPVIENNNGENRLNVIILEITVQSLQYLINENWQFVPHSNTIFFDGYI
                     APGWTDYPVTELTVGDSLRLYHVDDSKERECWLVINNPLATVKLCDNNLFITDVQAAD
                     LLCAISNEAVMDRIYCVIGTIHVDIHMLRNAKKDDIIDSTGYHLFGGCRLIRNNTTIA
                     YGSIVKINEDFYFTVSLVCD"
     gene            922..1437
                     /locus_tag="ACHY1N_005356"
     CDS             922..1437
                     /locus_tag="ACHY1N_005356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001374266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein EspH"
                     /protein_id="HFS4047454.1"
                     /translation="MSSSLSGIILNTSLTSHHMSWGKFSRTLHVLNEDIVDEIQLKAR
                     TQQRHHRVYSEMADYSVVSFRGKEYSVRFIKDYKTDNYVYKVQKMTQESGCLSRLFSF
                     LSGGVTKALESKLNERHITPLSPTWFPRTPLEGVLTERGLSSLLRCVQSTENLDYSNA
                     MISNSFSNSVV"
BASE COUNT          483 a          258 c          353 g          528 t
ORIGIN      
        1 atgaaaatta atgattttta cttgccattg ttgtcagtca taggaaccgg tcgcctctat
       61 attacgcctg aagggcatgc ttgccatgca tattttcgcg aagtcagcgg taatggtatc
      121 cgcttcacgt taacatgctc aggctatgag gggcgttttt ggatatcaga agaacagttc
      181 attcagtggt gccaggagtt attcccgtat agcgaaagcc ggctgatacc ggaagatatg
      241 ataaaactca tgatcttatg ggtaatgcag actgctttac cagaaggtga tgtgtctgtt
      301 gatgatgttc aatttacgat gctaaataaa gatgtttatc cggtaataga aaataataat
      361 ggagaaaaca gacttaatgt aattatactc gaaataacgg tacagagttt acaatatcta
      421 attaatgaaa attggcaatt tgttccacat tctaatacca ttttctttga tgggtatatt
      481 gctcctgggt ggactgatta cccggttaca gagctgactg ttggtgatag tttaaggctc
      541 tatcatgttg atgacagcaa agaaagagag tgttggcttg ttattaataa ccctttagca
      601 accgtaaaac tttgtgataa taatttattt attacggatg tccaggctgc agatttgtta
      661 tgtgctatca gcaatgaggc tgtaatggat cgcatttatt gtgtgattgg aacaattcat
      721 gttgatatac atatgttgcg caatgccaaa aaagatgata ttatcgattc aactggatat
      781 catctttttg gtgggtgccg gttaatacgc aataatacga ctatagcata cgggagcatt
      841 gtaaaaatca acgaagattt ttattttact gttagtttag tatgtgatta atcaggaata
      901 agttatatag ggagatgtat catgtcgtca tcgttatcag gaataatact caatacttcg
      961 ctgacaagcc accatatgtc atggggcaag tttagcagaa ctcttcatgt attgaatgaa
     1021 gatatcgtag atgaaattca gcttaaagcc cgaacacaac aacgccacca tcgagtatat
     1081 tcagaaatgg cggattactc cgttgtctcc tttcggggca aagaatattc tgttcgtttt
     1141 attaaagatt acaaaacaga taattatgtg tacaaagtac aaaagatgac tcaggaaagt
     1201 gggtgtctct caagattatt tagctttctt tctggcggtg tgactaaggc tttggaaagt
     1261 aaactaaatg agaggcatat cactccactt tctccaacct ggtttcctcg aactccactg
     1321 gagggggtct taacggaaag aggattatct tctttattac gttgcgtaca gtctactgaa
     1381 aaccttgatt atagtaatgc tatgatatca aactctttct ctaactctgt agtgtgatta
     1441 tcatttgagc tttcctcctg gtttaactcc agaataattg tgattctgga gtttttctgt
     1501 ttgttttatg tcgataatac attgttttta ggaaaatatg ggatgaatat tcagagtgag
     1561 tttggctggc agaagtcaga gattctgtga tgaggagggg attgagctga atggatgaat
     1621 tc
//
LOCUS       DAZUDJ010000259         1619 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.264, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000259 DAZUDJ010000000
VERSION     DAZUDJ010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1619
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.264"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..120)
                     /locus_tag="ACHY1N_005357"
     CDS             complement(<1..120)
                     /locus_tag="ACHY1N_005357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051495 - positive regulation of
                     cytoskeleton organization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HFS4047455.1"
                     /translation="MSDKLSGITHPDDNHDRPWWGLPCTVRPCFGARLVQEGNR"
     gene            complement(283..504)
                     /locus_tag="ACHY1N_005358"
     CDS             complement(283..504)
                     /locus_tag="ACHY1N_005358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HFS4047456.1"
                     /translation="MKIITRGEAMRIHQQHPASRLFPFCTGKYRWHGSTEAYTGREVQ
                     DIPGVLAVFAERHKDSFGPYVRLMSVTLN"
     gene            complement(567..1043)
                     /locus_tag="ACHY1N_005359"
     CDS             complement(567..1043)
                     /locus_tag="ACHY1N_005359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HFS4047457.1"
                     /translation="MQQLSFLPGEMTPGERSLILRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGNQVFSFAEHGLL"
     gene            complement(1059..1544)
                     /locus_tag="ACHY1N_005360"
     CDS             complement(1059..1544)
                     /locus_tag="ACHY1N_005360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HFS4047458.1"
                     /translation="MKTISHNSTTSSVSVTAASGNDQPQLVATIVPDEQRISFWPQHF
                     GLIPQWVTLEPRIFGWMDRLCEDYCGGIWNLYTLNNGGAFIAPEPDDDDGETWVLFNA
                     MNGNRTEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRII
                     D"
BASE COUNT          374 a          411 c          472 g          362 t
ORIGIN      
        1 gcggttaccc tcctgcacca gacgtgcccc gaaacagggc ctcactgtgc agggaagccc
       61 ccaccagggg cggtcgtgat tgtcgtcggg atgagttatc ccggagagtt tgtctgacac
      121 gataaaatcc tctctgaaaa gtggttaaga atggtttaac gatgacaggt cagccggcgc
      181 gctgaccggt ttcggtgaag atgtatgcat tgacgagaat ggcctcatcc acagcggcgt
      241 ctgagtccat ctggtcgtac tcgttttccg ggtgacggaa catcagttca gggtgacgct
      301 catcagccgg acatacgggc caaaactgtc cttatggcgt tcagcaaaca cggccagcac
      361 accgggaata tcctgcactt cacgaccggt atacgcttca gtgctgccgt gccagcggta
      421 tttgccggta cagaaaggaa aaagacggga tgccggatgt tgttggtgaa tacgcatggc
      481 ttcaccacgg gtgatgattt tcatagtgtg atacctctga agacagaaga taaaagtgaa
      541 aacaagcgtg atgtggttgt gacgggttaa agcagaccat gttcggcaaa ggagaaaacc
      601 tggttgccac cgactatcag atggtccggc acccggatat ccaccaggcc cagtgcctgt
      661 accagacgtt ccgtgataag gcggtctgcc ttgctgggtg tgacttcacc ggacgggtga
      721 ttgtgcgcca gcaccacggc agcggcattg tggtacaggg cgcgtttaat cacttcccgg
      781 ggatggactt ccgtgcggtt gatggtgccg gtgaagaggg tttcaccggc aatcaactga
      841 ttctggttat tcagatacag cacccggaat tcttcacgct ccagtcccgc catgttcaga
      901 atcagccatt cccgtgccgc acgggtggag gtgaaggcca cgccgggctc atgaagatgg
      961 cggtccaggg ttttcagggc ccgcagaatg agactgcgct cgccgggcgt catctctccg
     1021 ggcagaaagg aaagttgttg cattgtgctt ctctccattc agtcgatgat gcgcataatg
     1081 gcgctgcatt ccggatgctg cagggcgtaa tcccgcaacc ggtaataatg gaccgtcatg
     1141 gcataacact ccgtacgaca ggcatgatga ctgtacgtca tcagacaggc ggcaatgccg
     1201 gcggcttccg ggctcatttc agtgcggtta ccgttcatgg cattgaacag tacccatgtt
     1261 tcgccatcat cgtcatccgg ttcgggcgct ataaatgcgc caccgttgtt cagtgtgtac
     1321 agattccaga taccaccgca gtagtcttcg caaagacggt ccatccagcc gaagatacgg
     1381 ggctctaggg tcacccactg tggaatgagg ccaaaatgct gcggccagaa gctgatgcgc
     1441 tgttcatcag ggactatggt ggcaaccagc tgaggctggt cattccctga tgcagcggtt
     1501 acggaaacag aagatgtggt ggaattatgt gaaatggttt tcatgaaatg actccttaaa
     1561 ggacaaataa atgcgtggtt ttcagggtaa tgactgaatc agcgcaggct ctccagcag
//
LOCUS       DAZUDJ010000260         1618 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.265, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000260 DAZUDJ010000000
VERSION     DAZUDJ010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1618
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.265"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..203
                     /locus_tag="ACHY1N_005361"
     CDS             <1..203
                     /locus_tag="ACHY1N_005361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFS4047459.1"
                     /translation="IAEPPDKRRRDLDNILKAPLDALTHAGLLMDDEQFDEINIVRAQ
                     PVSGGRLGVKIYPIMLEGQVKK"
     gene            200..1021
                     /locus_tag="ACHY1N_005362"
     CDS             200..1021
                     /locus_tag="ACHY1N_005362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HFS4047460.1"
                     /translation="MKLEDLPKYYSPKSPGLTDASASTSKDTLSITDVMAAQGMTQNW
                     AEMGFSAFLGKMGISMNDRERATELLTEYALSRCDRVAALRKLPAEIKPAVMRIMASY
                     AFEDYARSAASKKQCPCCHGKKFIESEVFTNKIQYPDGKPPVWAKCTKGVYPSYWEEW
                     KKVREVVKVACPECGGKGEVSTACKDCRGRGVAIHREESVKRGMPVIRDCQRCGGRGY
                     ERLPSTEAFNAICNVTDAISLDTWKKTVKRFYDTLVVQFDIEEAWAEQQLKKVTR"
     gene            1259..1618
                     /locus_tag="ACHY1N_005363"
                     /pseudo
     CDS             1259..1618
                     /locus_tag="ACHY1N_005363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001448682.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
BASE COUNT          427 a          315 c          477 g          399 t
ORIGIN      
        1 ttattgccga gccaccggat aagcgccgcc gtgacttgga caatattctg aaagcgccgc
       61 tggatgcgct gacgcatgcg gggttgctaa tggacgatga gcagtttgat gaaatcaata
      121 tcgttcgtgc tcagccagta tctggtggac gtctgggggt gaagatttac cccataatgc
      181 ttgaagggca ggtcaaaaaa tgaaactgga agatttaccg aaatactact ccccaaaatc
      241 ccccggcctg actgatgcat cggcctcaac gtcgaaagat acgctgagta tcactgatgt
      301 gatggctgcg cagggcatga cacagaattg ggctgagatg gggttttctg cgttccttgg
      361 gaaaatgggc attagtatga atgacagaga gcgggcaaca gaattgctga cagaatatgc
      421 actcagtcgg tgtgatcgcg tggcggcgtt aagaaaactc ccggcagaaa taaaaccggc
      481 agtgatgcgt attatggctt cgtatgcgtt tgaagattat gcccgtagcg cggcgagcaa
      541 aaaacagtgc ccctgttgtc acggaaaaaa atttattgaa agcgaggttt ttacaaacaa
      601 gatccagtat ccggatggta agccgccagt gtgggcaaag tgcacaaaag gcgtgtatcc
      661 gtcttactgg gaggaatgga aaaaagtcag ggaggtggta aaagttgcct gtccggagtg
      721 tggagggaag ggggaggttt ccaccgcctg taaagattgt cgtgggcgcg gtgttgccat
      781 tcatcgtgaa gagtcggtaa aacgtggtat gcctgttatc agagactgcc agcgttgtgg
      841 tggtcgtggc tatgaaagat taccttcaac ggaggcattt aatgccatat gtaatgtaac
      901 cgatgccata tctcttgata catggaaaaa aacagttaaa cgtttttacg atacgctggt
      961 ggtgcagttt gatattgaag aagcatgggc agaacaacaa ctgaaaaagg tgaccagata
     1021 gctttgttga tttttcccga atctgtggta aatttgccct aacgatgggc gttttatgcc
     1081 tgacgttaga agatttttta cacccgtcgc taggcgggtt tttttatgac tgaaatcacg
     1141 ccagtacagt aaacgcgctg gtggttgtga ataccggtct ttcagcttgc tggctttttc
     1201 gacaagagtt attggtgtgt cacgttaacc ggaaaaagga aagtttgaga aacgcgatct
     1261 ggcacaggcg gttattaatg ctgcctacct ggtggcctgt gcagatggtg aatgtgaggc
     1321 ttcctagaaa gcgaagatcg aacaggtact gcgtaatcag cctgcgctgt ccgcgtttac
     1381 gtcagaaatt aatgcgatta gcgcaaccat tatcggtcag ctggatacga actttaaaat
     1441 tggtcgtcgt gcggcgttac gtgagatcga ggatgtgaaa cacgatacgc gtgaagcgga
     1501 agatgtgctg gatgtggcgg tggccattgc ggaggcagac ggcgaaattg agccggaaga
     1561 gcgcaaggtg ctggaagaga ttgccggtgt tctgggtctt cgtctggaga atcaccag
//
LOCUS       DAZUDJ010000261         1603 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.266, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000261 DAZUDJ010000000
VERSION     DAZUDJ010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1603
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.266"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..288
                     /locus_tag="ACHY1N_005364"
     CDS             <1..288
                     /locus_tag="ACHY1N_005364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047461.1"
                     /translation="AGPVGATGPQGPKGDPGETQIRFRLGPASIIETNSNGWFPGTDG
                     ALITGLTFLDPKDATQVQGLFQHLQVRFGDGPWQDVKGLDEVGSDTGRTGE"
     gene            290..559
                     /locus_tag="ACHY1N_005365"
     CDS             290..559
                     /locus_tag="ACHY1N_005365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047462.1"
                     /translation="MNVLKKLMQRLCGCGKHDDREHGELLTAQLRLGPADILESDENG
                     IIPEQDRVITQVVILDADKKQIQCVVRPLQILRADGTWENIGGMK"
     gene            670..1251
                     /locus_tag="ACHY1N_005366"
     CDS             670..1251
                     /locus_tag="ACHY1N_005366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004842 - ubiquitin-protein transferase
                     activity [Evidence IEA];
                     GO_process: GO:0044403 - biological process involved in
                     symbiotic interaction [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector NleG family protein"
                     /protein_id="HFS4047463.1"
                     /translation="MPGLVSYISSTSFANEMAEMRQQVMEGQIGGFLLGGERVRVSYI
                     LDTGRFLAESEGLGVVYAELLNIVFNDGVDALRNRMLSVLPGMAAQRQENSLQAKISE
                     CTFTVDIEKLHCTGEVLQCPITLEQPEKGIFVKNSDGSDVCTLFDAAAFSRLTGEGLP
                     HPLTREPITASIIVKHEECIYDDTRGNFVIKGN"
     gene            1319..>1603
                     /locus_tag="ACHY1N_005367"
     CDS             1319..>1603
                     /locus_tag="ACHY1N_005367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector protein NleG8"
                     /protein_id="HFS4047464.1"
                     /translation="MPVTTLSIPSISQLSPAGVQSLQDAARLESGIRISIGSGQYSVH
                     YVQLLDGFSVEPVRGGLLDRLLGREHRMERRAVALERQLNGGVDFLSSVNN"
BASE COUNT          444 a          292 c          455 g          412 t
ORIGIN      
        1 gctggcccgg tgggggcaac cggacctcag ggaccgaagg gcgacccggg ggagacacaa
       61 atccgttttc gtctggggcc ggcgagcatt attgagacaa acagcaatgg ctggttcccg
      121 ggtacagatg gtgcgctcat caccggactg acctttcttg accccaaaga tgccacacag
      181 gttcaggggc tgtttcagca tttgcaggtc aggtttggtg acgggccgtg gcaggatgtc
      241 aaggggctgg atgaagtggg cagtgataca ggcagaacag gagaatgaca tgaacgtact
      301 aaaaaaactt atgcagcgtc tgtgcggttg cggaaagcat gatgaccgtg aacacgggga
      361 gttacttaca gcacagctgc gactggggcc ggcagacatc ctggagtcag atgagaatgg
      421 cattatcccg gagcaggaca gggtaatcac gcaggtggtg atactggatg cggataaaaa
      481 gcagatacag tgcgtggtaa gaccgctgca aatcctgcgt gctgacggga cgtgggaaaa
      541 tattggcggg atgaaatagc cgacagtttc acaaaaaccg gagtccggct ccggtttttg
      601 ttgtcatgta tggggaatgt ttgttatgaa gcccagagga aatatttatc tgtatgaagg
      661 aatatggtaa tgcctggatt agtatcatat atatcatcga cctcattcgc gaatgagatg
      721 gcggagatgc gtcagcaggt aatggaaggg cagattggtg gatttctcct gggtggggag
      781 agagttagag tttcttatat actagataca ggccgttttt tagcagaaag tgaagggctg
      841 ggagtggttt atgcagaatt attgaatatt gtttttaatg atggagttga tgcgctcaga
      901 aacaggatgt taagcgtgct tcctggaatg gcggcgcaac gacaagagaa ctctctgcag
      961 gccaaaatat cggaatgtac ctttactgtt gatattgaaa aacttcactg tactggtgag
     1021 gtgcttcaat gtccaattac actggagcag cctgaaaaag gtatttttgt gaagaattca
     1081 gatggttcag atgtatgtac tttatttgat gccgctgcat tttctcgttt gactggtgaa
     1141 ggcttacccc acccactgac ccgggaacca ataacggcat caataattgt aaaacatgaa
     1201 gaatgcattt atgacgatac cagaggaaac ttcgttataa agggtaattg aaatgaacat
     1261 taccctttat ttaatgaaac atcctgcaaa ctgatatgaa ttactgaatg aggtttttat
     1321 gcctgttacc accttaagta tcccaagtat atctcaatta tctcctgcag gagtgcagtc
     1381 tttgcaggat gcagccagac ttgaaagtgg aataagaata tccattggta gtggccaata
     1441 ttctgttcac tatgtccaac tactggatgg attttcagtt gaaccggtga gaggaggctt
     1501 actggatagg ctattggggc gtgagcatcg aatggagaga agggctgtgg ctctggaaag
     1561 gcaattaaat ggaggtgtcg attttttaag tagtgttaat aac
//
LOCUS       DAZUDJ010000262         1581 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.267, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000262 DAZUDJ010000000
VERSION     DAZUDJ010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1581
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.267"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(207..317)
                     /locus_tag="ACHY1N_005368"
                     /pseudo
     CDS             complement(207..317)
                     /locus_tag="ACHY1N_005368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885581.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            complement(364..651)
                     /gene="nleC"
                     /locus_tag="ACHY1N_005369"
                     /pseudo
     CDS             complement(364..651)
                     /gene="nleC"
                     /locus_tag="ACHY1N_005369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308874.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector zinc
                     metalloprotease NleC"
     gene            complement(685..>1581)
                     /gene="nleB2"
                     /locus_tag="ACHY1N_005370"
     CDS             complement(685..>1581)
                     /gene="nleB2"
                     /locus_tag="ACHY1N_005370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector arginine
                     glycosyltransferase NleB2"
                     /protein_id="HFS4047465.1"
                     /translation="KEYELKVIDEKTPILFQWFEPNPERYKKDEVPIVNTKQHPYLDN
                     VTNAARIESDRMIGIFVDGDFSVNQKTAFSKLERDFENVMIIYREDVDFSMYDRKLSD
                     IYHDIICEQRLRTEDKRDEYLLNLLEKELREISKEQDSLISMYAKKRNHAWFDFFRNL
                     ALLKAGEIFRCTYNTKNHGISFGEGCIYLDMDMILTGKLGTIYAPDGISMHVDRRNDS
                     VNIENSAIIVNRSNHPALLEGLSFMHSKVDAHPYYDGLGKGVKKYFNFTPLHNYNHFC
                     DFIEFNHPNIIMNTSQYTCSSW"
BASE COUNT          509 a          335 c          235 g          502 t
ORIGIN      
        1 aattccatga acaccccaaa tttacagaag atggtgatag catacatttc aaccttcaaa
       61 atgaatcaat ctttactttc ttaacaaaca tcaccatgac atgacaacaa aaaactggaa
      121 attaactatt gtttttgagt atctggcaac tcattcatcc ttccagcatc ccgtcagacg
      181 aacgtttacg aactataaat caggtattac tggccctcga aatctggaga tactgacgta
      241 tcaacacggt tcagtaacac ccgatacctc ttccagactg tcaacaacga tgtctcttca
      301 tccgttgcga tctgcagcat cctgaatatg aatgccatag cttacggcat cacgaaaagt
      361 ttatgagcgg ctcaaagcat caagtatagt attactaatc atatcgaccg tatgctgatc
      421 aatgagtctg ccacgactgt catggacggc gcgtattaca ctttcgtata cgttgcttaa
      481 atctgctgcg gaaagtggta ttcgcttacc tatatccaaa acgtaatccg cataggcatt
      541 ttcagcacga ttaggagcaa tgggagcaga gtatcctgcc ggggcggaaa agttgaagtt
      601 ggactgtaat gagggaattt tcatgtttat atctaatacc ctgcaaatca tttattacaa
      661 caaaataaac tatatcaaat tcatttacca tgaactgcat gtatactgac ttgtgttcat
      721 gattatatta gggtggttaa actcaataaa gtcacaaaaa tgattataat tatgtaatgg
      781 tgtaaaatta aaatatttct taactccttt ccccaaacca tcataatatg gatgagcatc
      841 tactttacta tgcataaaag aaagtccctc aagtagagca ggatgattac tacggttaac
      901 aattattgca ctattttcaa tatttacact atcattacga cgatccacat gcattgaaat
      961 tccatcagga gcatatattg taccaagctt acctgtaagt atcatatcca tatcaagata
     1021 gatacacccc tccccgaatg aaataccgtg attctttgta ttatatgtgc acctgaatat
     1081 ctctcctgct tttaataagg ctaaatttct gaagaaatca aaccatgcat gatttctttt
     1141 ctttgcatac atagaaatca aagaatcctg ctcctttgaa atttccctca gctctttctc
     1201 taacagattc aacaagtatt catctctttt gtcttcagtt cgtaaccttt gttcacatat
     1261 aatatcatga taaatatctg atagttttct gtcatacata ctgaaatcaa catcttcccg
     1321 atagattatc attacatttt caaaatctcg ttccaatttt gaaaaagcag tcttttggtt
     1381 gactgaaaaa tcgccatcaa caaaaatacc tatcatacga tcactctcta tccttgccgc
     1441 atttgtgaca ttatctaaat agggatgctg cttagtatta actattggaa cctcatcttt
     1501 cttatatcgt tcaggattag gttcaaacca ctgaaaaaga ataggcgttt tttcatcaat
     1561 gacctttaac tcatattcct t
//
LOCUS       DAZUDJ010000263         1569 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.268, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000263 DAZUDJ010000000
VERSION     DAZUDJ010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1569
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.268"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1506
                     /locus_tag="ACHY1N_005371"
     CDS             <1..1506
                     /locus_tag="ACHY1N_005371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HFS4047466.1"
                     /translation="KLTGSTVLNGAIDPTNVTLASGATWNIPDNATVLSVVDDLSHAG
                     QIHFTSTRTGKFVPATLKVKNLNGQNGTISLRVRPDMAQNNADRLVIDGGRATGKTIL
                     NLVNAGNSASGMATTGKGIQVVEAINGATTEEGAFVQGNRLQAGAFNYSLNRDSDESW
                     YLRSENAYRAEVPLYASMLTQAMDYDRILAGSRSHQTGVSGENNSVRLSIQGGHLGHD
                     NNGGIARGATPESSGSYGFVRLEGDLMRTEVAGMSVTAGIYGAAGHSSVDVKDDDGSR
                     AGTVRDDAGSLGGYLNLTHTSSGLWADIVALGTRHSMKASTDNNDFRTRGWGWLGSLE
                     TGLPFSITDNLMLEPQLQYTWQGLSLDDGKDNAGYVKFGHGSAQHVRAGFRLGSHNDM
                     TFGEGTSSRAPLRDSAKHSVSELPVNWWVQPSVIRTFSSRGDMRVGTSTAGSGMTFSP
                     SQNGTSLDLQAGLEARVRENITLGVQAGYAHSVSGSSAEGYNGQATLNVTF"
BASE COUNT          349 a          448 c          470 g          302 t
ORIGIN      
        1 aagctgaccg gcagcactgt gctgaacggt gccattgacc ccacgaatgt cactctcgcc
       61 tccggtgcca cctggaatat ccccgataac gccacggtgc tgtcggtggt ggatgacctc
      121 agccatgccg gacagattca tttcacctcc acccgcacag ggaagttcgt accggcaacc
      181 ctgaaagtga aaaacctgaa cggacagaat ggcaccatca gcctgcgtgt acgcccggat
      241 atggcacaga acaatgctga cagactggtc attgacggcg gcagggcaac cggaaaaacc
      301 atcctgaacc tggtgaacgc cggcaacagt gcgtcaggga tggcgaccac cggtaagggt
      361 attcaggtgg tggaagccat taacggtgcc accacggagg aaggggcctt tgtccagggg
      421 aacaggctgc aggccggtgc ctttaactac tccctcaacc gggacagtga tgagagctgg
      481 tatctgcgca gtgaaaatgc ttatcgtgca gaagtccccc tgtatgcctc catgctgaca
      541 caggcaatgg actatgaccg gattctggca ggctcccgca gccatcagac cggtgtaagc
      601 ggtgaaaata acagcgtccg tctcagcatt cagggcggtc atctcggtca cgataacaat
      661 ggcggtattg cccgtggggc cacgccggaa agcagcggca gctatggctt cgtccgcctg
      721 gagggtgacc tgatgagaac agaggttgcc ggtatgtctg tgaccgcagg gatatatggt
      781 gctgcaggcc attcttccgt tgatgttaag gatgatgacg gctcccgtgc cggcacggtc
      841 cgggatgatg ccggcagcct gggcggatac ctgaatctga cacatacatc ctccggcctg
      901 tgggctgaca ttgtggccct gggaacccgc cacagcatga aagcgtcaac ggacaataac
      961 gacttccgca cccggggttg gggctggctg ggttcactgg aaaccggtct gcccttcagt
     1021 atcactgaca acctgatgct ggagccacaa ctgcagtata cctggcaggg actttccctg
     1081 gatgacggta aggacaacgc cggttatgtg aagttcgggc atggcagtgc acaacatgtg
     1141 cgtgccggtt tccgtctggg cagccacaac gatatgacct ttggcgaagg cacctcatcc
     1201 cgtgcccccc tgcgtgacag tgcaaaacac agtgtgagtg aattaccggt gaactggtgg
     1261 gtacagcctt ctgttatccg caccttcagc tcccggggag atatgcgtgt ggggacttcc
     1321 actgcaggca gcgggatgac gttctctccc tcacagaatg gcacatcact ggacctgcag
     1381 gccggactgg aagcccgtgt ccgggaaaat atcaccctgg gcgttcaggc cggttatgcc
     1441 cacagcgtca gcggcagcag cgctgaaggg tataacggtc aggccacact gaatgtgacc
     1501 ttctgacaga accatcgcct ctctgtggtc ccggtcatca tgaccgggac ccggaccggc
     1561 gcaacggat
//
LOCUS       DAZUDJ010000264         1563 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.269, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000264 DAZUDJ010000000
VERSION     DAZUDJ010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1563
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.269"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(108..320)
                     /locus_tag="ACHY1N_005372"
                     /pseudo
     CDS             complement(108..320)
                     /locus_tag="ACHY1N_005372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309678.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            470..1138
                     /locus_tag="ACHY1N_005373"
     CDS             470..1138
                     /locus_tag="ACHY1N_005373"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4047467.1"
                     /translation="MVKLMKKNTDDGAKIYTPLTLKLYDWWVLGVSNRLAWGCPTKEH
                     LLPHFLEHLGNNHLDIGVGTGFYLTHVPESSLISLMDLNEASLNAASTRAGESKIKHK
                     INHDVFEPYPAALHGQFDSISMFYLLHCLPGNISTKSCVIRNAAQALTDDGTLYGATI
                     LGDGVVHNSFGQKLMRIYNQKGIFSNTKDSEEGLTHILSEHFENVKTKVQGTVVMFSA
                     SGKK"
BASE COUNT          471 a          348 c          272 g          472 t
ORIGIN      
        1 ttgtatgaaa tcgtctcatg tacacggtcc ttttttcgcc gaaaactgat attactttaa
       61 tcaaaagttg acgtgccaga ttcgaagtaa atttataaaa tatcaaatca atatacattt
      121 tgcaccttcg agatagtaat gactgttact gtaacatgag ttacaaacag cttcataccc
      181 agagctactg atgtatcaac tcgattcaac aatacccgat atttattcca tgcctccagc
      241 aacgatcttt cttcctccgt tgcgatttcc agatctacag catcctgcag tggcgcaata
      301 tactcactga attcctggat gtagaactgt gtggtgacgg tcttccagcc attcagctcc
      361 tgctgtatcg aagcatacca ggctatttca atatcgctat gctgcggcag catttaaccc
      421 cttgtaattc atcgccataa ttgatttaat tcacaaataa aactataaca tggtgaaatt
      481 aatgaaaaaa aacacagatg atggggctaa aatttacaca ccacttaccc taaagcttta
      541 tgactggtgg gttttgggag tatcaaatcg gcttgcatgg ggatgtccta caaaggaaca
      601 ccttcttcca cactttctgg aacatttagg taacaaccat ctggatattg gtgttggaac
      661 tgggttttac cttactcacg tacctgagag tagtctgata tctttaatgg atttgaacga
      721 agctagcctg aacgcggcat ctacaagggc tggggaatca aaaattaaac ataaaattaa
      781 ccatgatgtt tttgaacctt atcccgcggc gttacatggt caatttgatt ccatttccat
      841 gttttacctt cttcactgcc tgcctggaaa tatatctaca aaaagctgtg taatacgcaa
      901 tgcggcgcag gccttaactg acgatggaac tctatacgga gccacaattc ttggcgatgg
      961 agttgtgcac aatagcttcg gtcaaaaact gatgcgcatt tacaatcaga aaggcatctt
     1021 ttcaaacaca aaagattccg aagaaggctt aacacatata ctctcagagc atttcgagaa
     1081 tgttaaaacc aaggttcaag gtactgtagt aatgttttcc gcttcaggga aaaaatagca
     1141 tccaaccgca gcacgttctt gcataaggcg tgtctgcggt ttttcaacta ttcagataca
     1201 tcactcccat cacattcatt cctccgcatc ataggcatat aggctatatc accttgatat
     1261 ttttcttctt cagataaaaa ctgttatcta tgtatacttt taaacccaat ccgtgtagag
     1321 tctctgcata agatagtttg cagttgccac ttcagcttgc gccataaacc gcctgatttt
     1381 tgccgccacc tgttagcatt cctgtatacc tgaaacgaca atgtttatct acgaacttta
     1441 agaacaccca ggataaaaat tgtcaactat atcatatata acacattact aattcgaggc
     1501 tatatgaaca gcatactgat aatcacttcg ctccttatca tattcagcat ttttagtcat
     1561 gct
//
LOCUS       DAZUDJ010000265         1555 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.270, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000265 DAZUDJ010000000
VERSION     DAZUDJ010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1555
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.270"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(34..231)
                     /locus_tag="ACHY1N_005374"
     CDS             complement(34..231)
                     /locus_tag="ACHY1N_005374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFS4047468.1"
                     /translation="MLKQQDMTETARVVFNELSVTEPATVGEIAQNTYLSRERCQLIL
                     TQLVMAGLADYQCGCYRRIQS"
     gene            complement(456..1010)
                     /locus_tag="ACHY1N_005375"
     CDS             complement(456..1010)
                     /locus_tag="ACHY1N_005375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1133 family protein"
                     /protein_id="HFS4047469.1"
                     /translation="MIYPEITGKSGEHLRLKTLESVWIQGKLRMWGRWSYIGDGKTGN
                     MFNQLLTSKKLTKTAINEALRRMKKAGLDKPELEAFLRDMINGNQKSWLAHCTDSEAL
                     IIDRVIGEVLAGYPGLLNVLSQRYVGRGMTKRKMAELLNDAHPEWSLRTCERRIEHWL
                     KVAEFILYKPMVMAFGIEKKVIAF"
     gene            complement(1019..1378)
                     /locus_tag="ACHY1N_005376"
     CDS             complement(1019..1378)
                     /locus_tag="ACHY1N_005376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFS4047470.1"
                     /translation="MRIEFVLPYPPTVNTYWRRRGSTYFVSKAGERYRRDVALIVRQQ
                     RLKLNLSGRLAIKIIAEPPDKRRRDLDNILKAPLDALTHAGLLIDDEQFDEINIVRGQ
                     LVSGGRLGVKIYKIESE"
     gene            complement(1391..>1555)
                     /locus_tag="ACHY1N_005377"
     CDS             complement(1391..>1555)
                     /locus_tag="ACHY1N_005377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HFS4047471.1"
                     /translation="GMGTKSHDIFTLPLCREHHNELHADPLAFEEKHGSQVDLIFRFL
                     DHAFATGVLG"
BASE COUNT          390 a          435 c          309 g          421 t
ORIGIN      
        1 accagccgcc catttaccac aaataaaaag ccttcaggac tgaatgcgtc tgtaacaacc
       61 gcactgatag tctgccagac ccgccataac cagctgggtc agtattaact ggcagcgttc
      121 gcgtgaaagg taagtattct gcgcaatctc cccgactgtc gccggttcgg taacgcttaa
      181 ttcattaaac accactctgg cggtttctgt catatcctgc tgttttagca tgtctttttc
      241 ccttttccgg ttaacgtgac ataccaataa ctcttgtcga aaaagccagc aagttgaaag
      301 accggtatta gcaaccacca gcgcgtttaa cgccccgtgc cgtttttcag tcataaaaaa
      361 acccgcaaaa agcgggctct ttcaaatgtc catgtctgct attcgcctcg cggtacagct
      421 ttgcgaagct taccgtaatt gaagcagttt ttacgtcaaa aagcaataac ttttttctct
      481 ataccaaaag ccataaccat tggtttgtac aaaataaatt ctgccacctt tagccaatgc
      541 tcaatgcgtc tttcacaggt tcttaaactc cattccggat gtgcatcatt cagcaattca
      601 gccattttgc gcttagtcat cccccgcccc acataacgct gactcagaac attgagcagc
      661 ccgggataac ctgccagtac ttcaccaata accctgtcga ttattaacgc ctctgaatcg
      721 gtacaatgtg ccagccagct tttttgattg ccgttgatca tatcccgcaa aaaagcctca
      781 agttcaggtt tgtccagacc cgcttttttc atcctccgga gcgcctcgtt aattgccgtt
      841 tttgtcagct ttttagaggt cagtaattgg ttgaacatat ttcccgtctt accgtcgcca
      901 atatacgacc aacgccccca catacgcagt ttcccctgga tccagacact ttccagcgtt
      961 ttcaggcgta aatgctcacc gcttttgcct gtaatttccg ggtatatcat atttatgctc
     1021 actcactttc aattttgtaa atcttcacgc ccagccgccc accagaaacg agctggccgc
     1081 gcacaatatt gatttcatca aactgctcgt cgtctatgag aagtccggca tgcgtcagcg
     1141 catccagtgg tgctttcagg atattgtcca ggtcacgacg gcgcttatcc ggtggctctg
     1201 caataatctt tatcgccagc cttccggaca ggtttaattt cagccgctgc tggcgaacaa
     1261 taagtgccac atcccggcga taacgctcac cggcttttga tacaaaatat gtgctgccac
     1321 gacgtcgcca gtaggtgttc accgtcggcg ggtaaggcaa aacaaactct atacgcatca
     1381 gtaacctctt ttacccgagc acgccggttg caaaggcgtg atcaagaaaa cgaaaaatta
     1441 aatcaacctg ggaaccatgc ttttcttcga acgccagcgg atccgcatga agctcgttgt
     1501 gatgctcccg acacagcggt agcgtgaaaa tatcgtggga ttttgttccc attcc
//
LOCUS       DAZUDJ010000266         1553 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.271, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000266 DAZUDJ010000000
VERSION     DAZUDJ010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1553
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.271"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..274
                     /gene="ydcD"
                     /locus_tag="ACHY1N_005378"
     CDS             <1..274
                     /gene="ydcD"
                     /locus_tag="ACHY1N_005378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein YdcD"
                     /protein_id="HFS4047472.1"
                     /translation="ISIMVNNYRTHCGVVDINLNFFNDILYSVRLKNISKLENMEFCA
                     KKQRVYFSDKNKKASYKIINYGDYYDVDYYDNNLKNEVFDWIGKWS"
     gene            complement(189..374)
                     /locus_tag="ACHY1N_005379"
     CDS             complement(189..374)
                     /locus_tag="ACHY1N_005379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047473.1"
                     /translation="MIYITIFMILPCPVPCSHVFLYVFYIFLFLVLFIMTIYQSSQKL
                     HFSNCYHNNQHRNSLHN"
     gene            455..1553
                     /locus_tag="ACHY1N_005380"
                     /pseudo
     CDS             455..1553
                     /locus_tag="ACHY1N_005380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027427.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1-like element ISEc26 family transposase"
BASE COUNT          575 a          202 c          357 g          419 t
ORIGIN      
        1 tataagtata atggttaata attacaggac gcactgtgga gtggttgata taaatcttaa
       61 ttttttcaat gatattcttt atagcgtgcg attaaaaaac attagtaaac tggagaatat
      121 ggagttctgc gctaaaaaac aacgggtgta ttttagtgat aaaaacaaga aggctagtta
      181 taaaataatt aattatggag actattacga tgttgattat tatgataaca atttgaaaaa
      241 tgaagttttt gactggattg gtaaatggtc ataatgaaca acaccagaaa gagaaaaata
      301 taaaatacat acagaaagac atgagagcaa gggacggggc agggcaagat catgaaaatt
      361 gtgatgtaaa tcacgatttt catcttggct ttaacgccta caggtgatca aaatttaacc
      421 tttggaataa ctaaaaagat aaaaaaggac ccaggtgagt attcaaagtt tgcttgatta
      481 tatttcagtg atccctgata tacgacaaca aggaaaggtt aaacataaat tatctgctat
      541 tttgtttctc accgtatgtg cagtaattgc aggtgccgat gagtggcagg aaattgaaga
      601 ttttggacat gaaagacttg aatggctaaa gaaatatggt gattttgata atggcattcc
      661 ggtcgatgac accattgcac gcgttgtgag taacattgac agtttggcct ttgaaaagat
      721 gtttattgaa tggatgcagg agtgccatga aatcactgat ggtgaaatta tagcaataga
      781 tggaaagacc ataagaggct cctttgataa gggaaaaaga aaaggagcaa tccatatggt
      841 gagtgcattc tcgaacgaaa atggtgttgt actggggcag gtgaaaacgg aagccaaaag
      901 taatgagatt acagccattc cagagttgct taacctactg tatttaaaga aaaatttgat
      961 aaccattgat gctatgggct gtcagaaaga tatcgcttcg aagatcaaag ataaaaaagc
     1021 agattatctt ctggcagtaa aaggcaatca ggggaaatta catcatgcat tcgaggaaaa
     1081 atttcctgta aatgtgtttt ctaattataa aggcgattcg tttagtacgc aggagataag
     1141 tcatggaaga aaagaaacac gtttgcatat tgtcagtaac gtaacgcctg aacttttgtg
     1201 attttgaatt cgaatggaag ggattaaaaa agctttgtgt agcattgtca ttcaggcaga
     1261 agaaagaaga taaatcagca gaaggtgtaa gcatccgata ttatatttca tcaaaggata
     1321 tggatgctaa agaatttgca catgctatca gagcgcactg gctgatcgag cacagtcttc
     1381 attgggtgtt agatgtaaaa atgaatgaag atgccagccg gataagaaga ggaaacgcag
     1441 cctaaataat atctggaata aagaagatgg cactgaattt attaagagat tgcaaagaca
     1501 ttaagggtga agaggaaaag aaagaaggct gcgttaaaca cagggaaaga tca
//
LOCUS       DAZUDJ010000267         1546 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.272, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000267 DAZUDJ010000000
VERSION     DAZUDJ010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1546
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.272"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..356)
                     /locus_tag="ACHY1N_005381"
     CDS             complement(<1..356)
                     /locus_tag="ACHY1N_005381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4047474.1"
                     /translation="MNNVIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAY
                     LLAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLDGVRPFVRILSEK
                     VRARRGRPPKDEVRLVP"
     gene            484..1344
                     /locus_tag="ACHY1N_005382"
     CDS             484..1344
                     /locus_tag="ACHY1N_005382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4047475.1"
                     /translation="MKITDHKLSEGIALTFRVPEGNMKHPLIILCHGFCGIRNVLLPC
                     FANAFTEAGFATITFDYRGFGESEGERGRLVPAMQIEDIISVINWAEKQACIDNQRIG
                     LWGTSLGGCHVFSAAAQDQRVKCIVSQLAFADGDALITGEMNELERASFLSTLNKMAE
                     KKKNTGKEMFVGVTRVLNDDESKVFFEKVKAQHPEMDIKIPFLTVMETLQYKPAESAA
                     RVQCPVLVVIAGQDSVNPPEQGRALYDAVASGTKELYEEADACHYDIYEGTFFERVAA
                     VQTQWFKKYI"
BASE COUNT          420 a          303 c          406 g          417 t
ORIGIN      
        1 ggaaccagac ggacttcatc ttttggcggg cgtccgcgtc gcgcgcgcac tttttcggac
       61 aggatccgca caaacggtct tacaccatcc agatcaaatg attccggtgt cagcatccgg
      121 gcttcgccaa tacgcattcc ggtattccag agggtggcga acagcatatg gtgacgctga
      181 tccggcatat agaaaagaag ggcactcact tccggggcca gcaggtaggc cggtgtggcc
      241 cctgtggaag tggccattct tctcagggag agcgctgttg caaaatccac ccccggcgca
      301 atgggtaaca gggagacgcg ttctggtgaa ttctgcaggg gaatgacatt gttcatgagt
      361 tatttttcac gtagcacacg cactgtttat ggatactgat tgcgctgggc attctggtat
      421 tgtgactggt atgatgctgg cgctgattct gatgattaat aaacaacata acacaggata
      481 tttatgaaaa ttacggatca caaactttct gaaggtattg ctctgacatt tcgtgttcct
      541 gaaggaaata tgaaacatcc tttgattatc ttatgccatg gattttgcgg tatccggaat
      601 gttctgctcc cttgctttgc gaatgctttc acagaagcag ggttcgcaac gattactttt
      661 gattatcgtg gattcggtga gagtgaagga gaacggggcc gtctggttcc agcaatgcag
      721 atcgaagata ttatttcagt tatcaattgg gcagaaaagc aggcatgtat tgataatcag
      781 cgtatcgggt tatggggaac atcgctgggt ggttgtcatg tgttcagtgc agctgcgcaa
      841 gatcaaagag tgaaatgtat tgtcagccag ctggcttttg ctgatggtga tgctctgatt
      901 accggagaga tgaatgaatt ggagagagct tcttttctgt ccacactgaa taaaatggca
      961 gagaaaaaga aaaacacagg gaaggagatg tttgtggggg ttacacgggt actaaatgat
     1021 gatgagtcga aggtattctt cgagaaagtc aaagctcagc atcccgaaat ggatataaaa
     1081 atacctttcc ttactgtcat ggaaacgttg caatataaac cggccgagag cgcagccaga
     1141 gtccagtgtc cagtattggt tgttattgct ggccaggata gtgttaatcc accggaacag
     1201 ggaagagcat tatatgatgc tgttgcttct ggtactaaag aattatatga ggaagctgac
     1261 gcatgccatt atgatattta tgagggcaca ttttttgagc gggtagcagc tgtgcaaaca
     1321 caatggttta aaaaatatat ttaatagtga gcctgtgttt accattctgt gtaaatactt
     1381 tttcttaaaa gtgaccgtca aggcggtcac taaactttat aataaagagg catcgttcat
     1441 ttccgggagg cagactggat tgccagcccc ccacttttta ccaagctgca ggtatggggg
     1501 acacggacac tggtgttcac agaaaaaaat aaccatctct gaaatg
//
LOCUS       DAZUDJ010000268         1541 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.273, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000268 DAZUDJ010000000
VERSION     DAZUDJ010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.273"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            29..772
                     /locus_tag="ACHY1N_005383"
     CDS             29..772
                     /locus_tag="ACHY1N_005383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFS4047476.1"
                     /translation="MTQTESAILVHARRCAPAESCGFVIGTPEGERYQPCVNISAEPE
                     AYFRIAPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQIKSALPWWLVCRGEIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGITLPDFEREDDWWRNGQNLYLDNMAAT
                     GFYRVPLSSAQAGDILLCCFGASVANHAAIYCGNGELLHHLPEQLSKRERYSEKWQRR
                     THSVWRHRHWHASAFTGICNDLAAASACT"
     gene            769..1347
                     /locus_tag="ACHY1N_005384"
     CDS             769..1347
                     /locus_tag="ACHY1N_005384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310189.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HFS4047477.1"
                     /translation="MNTAAEAIRALSLQMPGFRRQMNEGWYQIRIRGEDTAPEAVYAR
                     LHEPLGEGAVIHIVPRLAGAGKGGLQIVLGAAAIVGSFFTAGASMALWGSALAAGGFS
                     ATTMLFSLGASMILGGVAQMLAPKAKTPEYRATDNGKQNTYFSSLDNMIAQGNPMPVP
                     YGEMLVGSRRISQDISTRDEGGDGKVVVIGRG"
BASE COUNT          324 a          389 c          496 g          332 t
ORIGIN      
        1 aataaacttt cgcagtaaat cctgttttat gacacagact gaatcagcga ttctggtgca
       61 tgcccggcgg tgtgcgcctg cggagtcgtg cggcttcgtg ataggcaccc cggagggcga
      121 acggtaccag ccctgcgtga atatctccgc agagccggag gcgtattttc gtattgcgcc
      181 ggaagactgg ctgcaggcag agatgcaggg ggagattgtg gcgctggttc acagccaccc
      241 tggtggtctg ccctggctga gcgaggccga ccggcggctg cagataaaga gtgccctgcc
      301 ctggtggctg gtctgccggg gggaaattca taaattccgc tgtgtgccgc acctgaccgg
      361 gcgtcgtttt gagcacgggg tgacggactg ttacaccctg ttccgggatg cataccatct
      421 ggcggggata acgctgccgg attttgagcg tgaggatgac tggtggcgca acggtcagaa
      481 cctttacctg gacaatatgg cggcgactgg tttttaccgg gtgcccctgt cctctgcaca
      541 ggcgggcgat atcctgctgt gctgctttgg cgcatcggtg gccaatcatg ccgccatata
      601 ctgcggcaac ggtgaactgc ttcaccatct gcctgaacaa ctgagtaaac gggagaggta
      661 ttctgaaaaa tggcaacgac gaacgcattc tgtctggcgt caccgccact ggcacgcatc
      721 tgccttcacg gggatttgca acgatttggc cgccgcctca gcctgtacgt gaacacggca
      781 gcggaagcca tccgtgccct gtcgctgcag atgccgggat tccgccgtca gatgaacgaa
      841 ggctggtacc agatacgtat tcgcggtgag gacacggcac cggaggcggt gtacgcccgt
      901 cttcacgaac ctctgggtga gggggcggtc atccatattg tgccgcgact ggccggggcc
      961 ggaaagggtg gactgcagat tgtgctgggg gcggcagcca tcgtgggctc tttcttcacg
     1021 gccggggcat caatggcgtt atggggttca gccctggcag ccggtggttt ttctgccacc
     1081 acgatgctgt tctcactggg tgccagcatg atactgggcg gtgtggccca gatgctggca
     1141 ccgaaggcaa aaacaccgga gtacagggcg acggataacg gtaaacagaa cacgtatttt
     1201 tcgtcactgg ataacatgat tgcccagggg aacccgatgc cggtgcctta tggtgaaatg
     1261 ctggttggtt cacgacggat atcccaggac atcagcaccc gtgatgaggg cggagacggg
     1321 aaagtggtgg ttatcgggcg gggatgaaaa taaaaaaatc ccgcagagtt agcggagctg
     1381 cgggagagaa cgatgaagat taacgttatg gagttatttt tcaggcatca aaaaagtaat
     1441 gcagcgtcat tattgcggct acaggcaatt gccggaaatg tgaagagttt cagaaatttt
     1501 attccgtcat gacacaggca ccctccgggg tgcctgttgt t
//
LOCUS       DAZUDJ010000269         1503 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.274, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000269 DAZUDJ010000000
VERSION     DAZUDJ010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.274"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..332
                     /locus_tag="ACHY1N_005385"
     CDS             <1..332
                     /locus_tag="ACHY1N_005385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310019.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047478.1"
                     /translation="GPAGPQGPKGETGVAGPVGATGPQGPKGDPGETQIRFRLGSGNI
                     IETNSNGWFPDTDGALITGLTFLDPKDATRVQGFFQHLQVRFGDGPWQDVKGMDEVGS
                     DTGRTGE"
     gene            334..603
                     /locus_tag="ACHY1N_005386"
     CDS             334..603
                     /locus_tag="ACHY1N_005386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047479.1"
                     /translation="MNILKKLMQRLCGCGKHDDREHGELLTAQLRLGPADILESDENG
                     IIPEQDRVITQVVILDADKKQIQCVVRPLQILRADGRWENIGGMK"
     gene            716..1291
                     /locus_tag="ACHY1N_005387"
     CDS             716..1291
                     /locus_tag="ACHY1N_005387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1076 domain-containing protein"
                     /protein_id="HFS4047480.1"
                     /translation="MPLTSDIRSHSFNLGVEVVRARIVANGRGDITVGGETVSIVYDS
                     TNGRFSSSGGNGGLLSELLLLGFNSGPRALGERMLSMLSDSGEAQSQESIQNKISQCK
                     FSVCPERLQCPLEAIQCPITLEQPEKGIFVKNSDGSDVCTLFDAAAFSRLVGEGLPHP
                     LTREPITASIIVKHEECIYDDTRGNFVIKGN"
     gene            1364..>1503
                     /locus_tag="ACHY1N_005388"
     CDS             1364..>1503
                     /locus_tag="ACHY1N_005388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector protein NleG8"
                     /protein_id="HFS4047481.1"
                     /translation="MPVTTLSIPSISQLSPAGVQSLQDAARLESGIRISIGSGQYSVH
                     YV"
BASE COUNT          411 a          290 c          409 g          393 t
ORIGIN      
        1 caggcccggc aggcccacag ggaccgaaag gagaaacagg tgtggctggc ccggtagggg
       61 caaccggacc tcaggggccg aagggcgacc cgggagagac gcaaatacgg ttccgtctgg
      121 ggtcgggaaa cattattgag acaaacagca atggctggtt cccggataca gatggcgcac
      181 tcatcaccgg actgaccttt cttgacccca aagatgccac acgggttcag gggttttttc
      241 agcatttgca ggtcagattt ggcgacgggc cgtggcagga tgtcaagggg atggatgaag
      301 tgggcagtga tacaggcaga acaggagaat gacatgaaca tactaaaaaa acttatgcag
      361 cgtctgtgtg gttgcggaaa gcatgatgac cgtgaacacg gggagttact tacagcacaa
      421 ctgcgactgg ggccggcaga catcctggag tcagatgaga atggcattat tccggagcag
      481 gacagggtaa tcacacaggt ggtgatactg gatgcggata aaaagcagat acagtgcgtg
      541 gtaagaccgc tgcaaatcct gcgtgctgac gggaggtggg aaaatattgg cgggatgaaa
      601 tagccgacgg gttcacaaaa accggagtcc tgctctggtt tttgttgtca cgtatggggg
      661 atgtttgtta cagctattta agtctggagt tcaaattaaa atagggagct ttgttatgcc
      721 attaacctca gatattagat cacattcatt taatcttggg gtggaggttg ttcgtgcccg
      781 aattgtagcc aatgggcgcg gagatattac agtcggtggt gaaactgtca gtattgtgta
      841 tgattctact aatgggcgct tttcatccag tggcggtaat ggcggattgc tttctgagtt
      901 attgcttttg ggatttaata gtggtcctcg agcccttggt gagagaatgc taagtatgct
      961 ttcggactca ggtgaagcac aatcgcaaga gagtattcag aacaaaatat ctcaatgtaa
     1021 gttttctgtt tgtccagaga gacttcagtg cccgcttgag gctattcaat gtccaattac
     1081 actggagcag cctgaaaaag gtatttttgt gaagaattca gatggttcag atgtatgtac
     1141 tttatttgat gccgctgcat tttctcgttt ggttggtgaa ggcttacccc acccactgac
     1201 ccgggaacca ataacggcat caataattgt aaaacatgaa gaatgcattt atgacgatac
     1261 cagaggaaac ttcgttataa agggtaattg aaatgaacat taccctttat tttatttaat
     1321 gaaacatcct gcaaactgat atgaattact gaatgaggtt tttatgcctg ttaccacctt
     1381 aagtatccca agtatatctc aattatctcc tgcaggagta cagtctttgc aggatgctgc
     1441 cagacttgaa agtggaataa gaatatccat tggtagtggc caatattctg ttcactatgt
     1501 cca
//
LOCUS       DAZUDJ010000270         1491 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.275, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000270 DAZUDJ010000000
VERSION     DAZUDJ010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.275"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1491
                     /locus_tag="ACHY1N_005389"
     CDS             <1..>1491
                     /locus_tag="ACHY1N_005389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1983 domain-containing protein"
                     /protein_id="HFS4047482.1"
                     /translation="TYGVWGLSLPSLRRRLFRCVSIRENTDGTFAITAVQHVPEKEAI
                     VDNGASFEPQSGTLNSVIPPAVQHLTVEVSAADGQYLAQAKWDTPRVVKGVRFSLRLT
                     SGSGEGSRLVTTAITADTEHRFSGLPPGEYTLTVRAINSYGQQGEPATTTFRINAPAV
                     PATIELTPGYFQITAVPRLAVYDPTVQFEFWFSETKIADTSQVETSARYLGTGSQWSV
                     SGPHIKPGKDFWFYVRSVNLVGKSAFVEASGRASNDAEGYLGLFREKIGKLHLAQGLW
                     ELIDNSQLADEMAEMKTSITETRNEITQTVSKTLEDQSATIQQIQRVQKDTNDDLAAL
                     YMLKVQKTKNGIPYVAGIGAGIEDTDGQPLSNILLLADRIAMINPEDGNTTPLFVAQG
                     NQLFMNDVFLKRLFAASITSSGNPPTFSLTPEGKLTARNADISGAITANTGTLNNVTI
                     NENCVIRGKLSANQIEGDLVKTVGKAFPRNNSYASGTVTVTVYDDQG"
BASE COUNT          364 a          393 c          455 g          279 t
ORIGIN      
        1 gacatacggt gtatggggac tctccctgcc gtcactgcgt cgtcgcctgt tccgctgtgt
       61 ctccatccgg gaaaacacgg acggcacctt tgccatcacg gcggtgcagc acgtaccgga
      121 aaaggaagcc atcgtggata acggggccag ctttgagccg cagtcaggca ccctgaacag
      181 cgtcatccct ccggcagtgc agcacctgac ggtggaggtg agcgcagctg acggccagta
      241 tctggcgcag gcgaaatggg acacgccgcg ggtggtgaag ggcgtgcgct tcagtctgcg
      301 actgaccagc ggaagcggag aaggcagccg tctggtgacc accgccatca ccgcggatac
      361 agagcaccgt ttcagcggtc tgccgccggg ggaatacacc ctgacggtca gggcgattaa
      421 cagttatggc cagcaggggg aaccggccac caccacgttc aggattaatg cacctgcggt
      481 acccgccacg attgagctga caccgggcta ttttcagata acagcggtcc cgcgtcttgc
      541 ggtgtatgac ccgacggtac agtttgagtt ctggttttcg gagacaaaaa tcgcagacac
      601 atctcaggtg gaaacctctg cccgttatct ggggaccggc agtcagtgga gtgtatccgg
      661 cccgcacatt aagcccggga aggatttctg gttttacgtg cgcagcgtca acctggtggg
      721 gaaatctgct tttgtggaag ccagtggccg ggccagcaat gatgcagaag ggtatctggg
      781 gctgtttcgg gaaaaaatag gaaaactgca tctggctcag gggctgtggg agctgataga
      841 caacagccag cttgcggatg agatggcgga gatgaagacc tccatcaccg aaacccgcaa
      901 tgaaatcaca cagacggtca gtaaaacgct ggaggaccag agcgccacca tacagcagat
      961 acagcgcgtg cagaaggaca caaatgatga ccttgctgca ctttacatgc tgaaggtaca
     1021 gaaaacaaaa aatggcatac cctatgttgc cggtattgga gcggggattg aggatactga
     1081 tggccagccc ctgagcaaca tactgctgct ggctgaccgt attgcgatga ttaacccgga
     1141 ggacggcaac accacgccgt tatttgtggc gcaggggaat cagttgttca tgaacgatgt
     1201 gttcctgaag cggctgtttg cggcgagtat cacgtcatcc ggcaaccccc cgacgttttc
     1261 cctgacgccg gaagggaagc tgacagccag gaacgcggat atcagcggag caattaccgc
     1321 gaataccggc acgctcaata atgtcaccat taacgagaac tgtgtcatca gagggaaact
     1381 gtctgcaaac cagattgaag gcgacctggt gaagacggtg gggaaagcct ttccccggaa
     1441 taacagttat gccagcggga cggtaaccgt cacagtttac gatgaccagg g
//
LOCUS       DAZUDJ010000271         1480 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.276, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000271 DAZUDJ010000000
VERSION     DAZUDJ010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.276"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1192
                     /locus_tag="ACHY1N_005390"
     CDS             <1..1192
                     /locus_tag="ACHY1N_005390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="terminase gpA endonuclease subunit"
                     /protein_id="HFS4047483.1"
                     /translation="QYLKFGDESTPFGLKWEKDSPESVFYLCEHHGCVIHQSELDQSN
                     GRWICENTGMWTRDGLTFFSARGDEIPPPRSITFHIWTAYSPFTTWVQIVYDWLDALK
                     DPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDKVVHYTAAVPARVVYLTAGIDSQRNR
                     FEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDAAINKKYCHADGTEMTISRVCW
                     DTGGIDGEIVYQRSKKHGVFRVLPVKGASVYGKPVITMPKTRNQRGVYLCEVGTDTAK
                     EILYARMKADPTPADEATSYAIRFPDDPEIFSQTEAQQLVAEELVEKWEKGKMRLLWD
                     NKKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEETTRPTLKELAAKLSGGVN
                     GYSR"
     gene            1176..1382
                     /locus_tag="ACHY1N_005391"
     CDS             1176..1382
                     /locus_tag="ACHY1N_005391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gpW family head-tail joining protein"
                     /protein_id="HFS4047484.1"
                     /translation="MVTVAELQALRQARLDLLTGKRVVSVQKDGRRIEYTVASLDELN
                     RAINDAESVLGTTRRRRRPLGVRL"
     gene            1379..>1480
                     /locus_tag="ACHY1N_005392"
     CDS             1379..>1480
                     /locus_tag="ACHY1N_005392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047485.1"
                     /translation="MKRTPVLIDVNGVPLRESLSYNGGGAGFGGQMAE"
BASE COUNT          356 a          347 c          463 g          314 t
ORIGIN      
        1 gcagtatctg aaatttggcg atgagtccac gccttttggg cttaaatggg agaaggacag
       61 ccccgaaagt gttttctacc tctgtgaaca tcatggctgc gtgatccatc agtctgaact
      121 ggaccagagc aacgggcggt ggatctgtga aaacacgggc atgtggaccc gtgacggtct
      181 gacgtttttc agcgcccggg gtgatgaaat tccgccgccg cgctccatca cgttccatat
      241 ctggacggcg tacagtccgt ttaccacctg ggtacagata gtctatgact ggctggatgc
      301 actgaaagat cccaacggcc tgaaaacctt tgtgaacacc acgctgggcg agacctggga
      361 agaagccgtg ggcgaaaaac tcgatcacca ggtactgatg gataaggtcg tgcattacac
      421 ggcggcggta cctgcccggg tggtttatct gacggcgggc attgactcgc agcgaaaccg
      481 ttttgagatg tatgtctggg gatgggcacc gggagaggaa gcttttctgg tggataaaat
      541 catcattatg ggccgtcccg atgaggaaga gacgctgtta cgtgtggatg cggcgatcaa
      601 caaaaaatac tgccatgcag acggaaccga aatgaccatt tcccgtgtct gctgggacac
      661 cggggggatc gatggtgaaa ttgtctatca gaggtcaaaa aaacacggtg ttttccgggt
      721 gctgccggta aaaggcgcat ctgtctatgg caagccggtg atcaccatgc cgaaaacccg
      781 caatcagcgg ggcgtgtatc tgtgtgaagt ggggacggac accgcaaaag aaattctcta
      841 tgcccgtatg aaagccgatc ccactcctgc ggatgaagcc acgtcgtatg ccatccgttt
      901 tcctgatgat ccggagattt tttcgcagac agaggcgcag caactggtcg cggaagagct
      961 tgtggagaag tgggaaaaag gaaagatgcg tctgctgtgg gataacaaaa agcggcgtaa
     1021 cgaagcgctg gactgcctgg tgtatgccta cgcggcatta cgtgtgtccg tgcaacgctg
     1081 gcagcttgat ctggctgtac tggcaaaatc ccgggaagaa gagacgaccc ggccaaccct
     1141 gaaagaactg gcagcgaagc tgtccggagg agtgaatggt tacagtcgct gaactacagg
     1201 cgctacgtca ggcgcgcctt gatttattaa ccggtaaacg ggtggtgtct gtccagaaag
     1261 atggtcgcag aattgaatat acggtggctt ctctggatga gcttaaccgg gcgatcaatg
     1321 atgcggagtc ggtactgggg acaacccgac gtcgccgtcg tccgctggga gtgaggttat
     1381 gaaacgaacg cctgtcctga ttgatgtgaa cggcgttccg cttcgtgaga gtctcagcta
     1441 caacgggggc ggcgcaggat ttggcgggca aatggcggag
//
LOCUS       DAZUDJ010000272         1438 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.277, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000272 DAZUDJ010000000
VERSION     DAZUDJ010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1438
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.277"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..108
                     /locus_tag="ACHY1N_005393"
     CDS             <1..108
                     /locus_tag="ACHY1N_005393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HFS4047486.1"
                     /translation="TDIRKDRCSKCMRGCEMRGMVANFGGFLSINKLSQ"
     gene            113..856
                     /locus_tag="ACHY1N_005394"
     CDS             113..856
                     /locus_tag="ACHY1N_005394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFS4047487.1"
                     /translation="MTETESAILAHARRCAPAESCGFVISTPEGDRYQPCVNISAEPE
                     AYFRIAPEDWLRAEMQGEIVALVHSHPGGLPWLSEADRRLQIKSALPWWLVSRGDIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGTEMPDFHREDDWWRNGQNLYLDNMEGT
                     GFYRVPLSSAQAGDILLCCFGASVPNHAAIYCGNGELLHHLPEQLSKRERYSEKWQRR
                     THSVWRHRHWHASVFTGIYNDLAAASACM"
     gene            853..1434
                     /locus_tag="ACHY1N_005395"
     CDS             853..1434
                     /locus_tag="ACHY1N_005395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000246308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HFS4047488.1"
                     /translation="MNTAAEAIRALSMQMPGFRRQMNEGWYQIRIAGDDTAPEAVYAR
                     LHEQLGEGTVIHIVPRLAGAGKGGLQIVLGAAAIVGSFFTAGASMALWGSALAAGGFS
                     ATTMLFSLGASMILGGVAQMLAPKAKTPDYRAMDNGRQNTYFSSLDNMIAQGNPMPVP
                     YGEMLVGSRRISQDISTRDEGGGGKVVVIGRQR"
BASE COUNT          293 a          377 c          467 g          301 t
ORIGIN      
        1 acggatatcc gtaaggacag atgcagcaag tgcatgcgcg ggtgtgagat gcgcggcatg
       61 gtggctaatt ttggcggttt cctttccatt aataaacttt cgcagtaaat ccatgacaga
      121 gacagaatca gcgattctgg cgcatgcccg gcggtgtgcg cctgcggagt cttgcggctt
      181 cgtgataagc acgccggagg gtgaccggta ccagccgtgc gtgaatatct ctgcagagcc
      241 tgaggcatat tttcgtattg ccccggaaga ctggctgcgg gcagagatgc agggggagat
      301 tgtggcactg gtccacagcc atcccggtgg cctgccctgg ctgagcgagg ccgaccggcg
      361 gctgcagata aaaagtgccc tgccctggtg gctggtcagc cggggtgaca ttcacaaatt
      421 ccgctgcgtt ccgcacctga ccggacggcg ctttgaacac ggggtgacgg actgttacac
      481 cctgttccgg gatgcgtacc atctggcggg gactgaaatg ccggattttc atcgcgagga
      541 tgactggtgg cgcaacggcc agaacctgta cctggacaat atggagggaa cgggctttta
      601 ccgggtgccc ctgtcctctg cacaggcggg cgatattctg ctgtgctgct ttggtgcttc
      661 ggtaccgaac catgccgcca tttactgtgg caacggtgag ctgcttcacc atctgcctga
      721 acaactgagt aaacgggaga ggtattccga aaaatggcaa cgacgaacgc attctgtctg
      781 gcgtcaccgc cactggcacg catctgtctt cacggggatt tacaacgatt tggccgccgc
      841 ctcagcctgt atgtgaacac ggcagcggaa gccatccgtg ccctgtcgat gcagatgccg
      901 ggattccgcc gtcagatgaa cgaaggctgg taccagatac gtattgccgg tgatgacacg
      961 gcaccggagg cggtgtacgc ccgtcttcac gaacagctgg gtgagggaac ggtcatccac
     1021 attgtgccgc gactggccgg ggccggaaag ggtggactgc agattgtgct gggggcggcg
     1081 gccatcgtgg ggtcgttctt cactgccggg gcatcaatgg cgttatgggg ttcagccctg
     1141 gcagccggtg gtttttctgc caccacgatg ctgttttcac ttggagccag catgattctg
     1201 ggtggtgtgg cccagatgct ggcaccgaag gcaaaaacac cggattaccg cgcaatggat
     1261 aacggcagac agaacacgta cttttcctca ctggacaaca tgattgctca ggggaacccg
     1321 atgccggtgc cttacggtga aatgctggtt ggttcacgac ggatatccca ggacatcagc
     1381 acccgtgatg agggcggggg cggaaaggtc gtggttatcg ggcggcagag gtaaaaag
//
LOCUS       DAZUDJ010000273         1429 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.278, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000273 DAZUDJ010000000
VERSION     DAZUDJ010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1429
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.278"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1429
                     /locus_tag="ACHY1N_005396"
     CDS             <1..>1429
                     /locus_tag="ACHY1N_005396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000264505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047489.1"
                     /translation="RKLNIFQNNQNVIINDFCPICFKEINNELERFSKVVRTDLRVNL
                     NFIYPLSTSSVHIEVQDGASIDELLISNVTKLLKKGLVFSSAPESFLNYGKYEDAVVI
                     SLRNSLFSGNELALDFSIRAIFTLVSETELVKVIHNLNHSFGYTNKKNNIEYSIFAAF
                     YMKVSSEVSGYKNYNIVCDALRSIMDLGRYIYDNEQYDEFYKLISPSLEHRAQYSLGD
                     PEYRFFDLYMSTVRDNILSKNYLAFSLNTRFLTEKFRYPESSDDGETLSIIENKMVSC
                     VRQVITLLIIRLCYLSEKSDGHQEELRIIKQNLMKWLAPSFLEDLFYKSGVYDVIFTV
                     PSEPDFDASRTLRDIPDYEVATFSINNDAFKAVSLLMTQTLFNKNNLNPIFIRNKKEF
                     IKNTKITTHELQSLISYLKGDEFSALLELINEGSSQETNRMEVAEHLESIISVKNELI
                     ANSIVSSDLDKVLVNKYIDKVSISLG"
BASE COUNT          493 a          187 c          256 g          493 t
ORIGIN      
        1 cgtaagttaa atattttcca aaataatcaa aatgtcatta ttaatgattt ttgtccaatt
       61 tgctttaaag aaattaacaa tgagctagag cgtttttcga aagtggtacg tactgattta
      121 cgcgtgaatc ttaactttat atatccacta tcaacctcat cggttcatat tgaagtgcaa
      181 gatggagcgt cgatcgatga gctattaatt agtaatgtta caaaactatt gaaaaaagga
      241 ttggtgttca gttcagctcc tgaaagcttc ttgaattacg gtaagtatga agatgcagta
      301 gttattagct taagaaatag tctttttagt ggtaatgagt tagcgttaga ttttagcata
      361 agagctatct tcacattagt tagtgaaact gaattagtta aagtaataca taacctcaat
      421 cactcttttg gttatactaa caaaaaaaat aatatagagt attcaatttt tgctgctttt
      481 tatatgaagg ttagttctga agtgagtggg tataaaaact ataatatagt gtgtgatgct
      541 cttcgatcga ttatggattt gggaaggtat atttatgata atgagcaata tgatgaattt
      601 tataaattga tatcaccgtc attggaacat cgtgctcaat atagtttagg tgatccagaa
      661 tatcgttttt ttgatttata tatgtcaacg gtgagagaca acatcttgtc aaagaattat
      721 ttggcattta gcctgaatac tcgattcttg actgagaaat ttcgttatcc agagtcatct
      781 gatgatggcg aaacccttag tatcattgag aacaagatgg tatcgtgtgt aagacaggtt
      841 ataactttac tgattattag gctgtgctat ttatctgaaa aaagtgatgg gcatcaggag
      901 gaattgagaa taataaaaca gaatttaatg aaatggttag caccttcatt cctagaagat
      961 cttttttata agagtggcgt gtatgatgtt atatttacag tcccatctga acctgatttt
     1021 gatgcaagta gaactttaag agatatacct gattatgagg ttgcaacctt ttcaataaat
     1081 aacgatgctt tcaaagcagt atccctttta atgactcaaa cattatttaa taaaaacaac
     1141 ctcaatccta tttttatacg taataaaaaa gagtttatta aaaatacaaa aataacaact
     1201 catgaactgc aatcacttat atcatatttg aaaggtgatg aattttcagc tttattagag
     1261 ttgattaatg aaggatcttc tcaagaaaca aatcggatgg aggttgcaga gcatcttgaa
     1321 agtataattt ctgtaaaaaa tgaattaatc gcaaattcta ttgtttcttc tgaccttgat
     1381 aaggttctgg ttaataaata catagataaa gtatcaatat cattaggtg
//
LOCUS       DAZUDJ010000274         1422 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.279, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000274 DAZUDJ010000000
VERSION     DAZUDJ010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1422
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.279"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..411
                     /gene="yqeJ"
                     /locus_tag="ACHY1N_005397"
     CDS             <1..411
                     /gene="yqeJ"
                     /locus_tag="ACHY1N_005397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YqeJ"
                     /protein_id="HFS4047490.1"
                     /translation="SYTAEKMIYNETCTANWVIFNDQGRANLTIDFMFNKKNKTGTVA
                     LSGTWQQGNRESKSIRRNIEYTWIENYDTAHLTSKKVNKFEIMDQVDDDRLVQLIPDF
                     YVFPEKSVSYNILKQGKHAFILSIGNRAIMHCAR"
     gene            complement(444..524)
                     /locus_tag="ACHY1N_005398"
     CDS             complement(444..524)
                     /locus_tag="ACHY1N_005398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047491.1"
                     /translation="MKDVDQNFDALDCHILREYLILLFYD"
     gene            complement(560..984)
                     /gene="yqeK"
                     /locus_tag="ACHY1N_005399"
                     /pseudo
     CDS             complement(560..984)
                     /gene="yqeK"
                     /locus_tag="ACHY1N_005399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417326.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein YqeK"
     gene            1178..>1422
                     /locus_tag="ACHY1N_005400"
     CDS             1178..>1422
                     /locus_tag="ACHY1N_005400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047492.1"
                     /translation="MKPRNINNSLSLQPLVPDQENKNKKNEEKSVNPVKITMGSGLNY
                     IEQESLGGKYLIHDLSIKIADISEEIIQQAILSAMSI"
BASE COUNT          527 a          233 c          225 g          437 t
ORIGIN      
        1 tcttacactg cagaaaaaat gatatataac gaaacatgca ctgcaaattg ggtaattttt
       61 aatgaccagg gacgagcaaa tcttaccatc gactttatgt ttaacaaaaa aaataaaaca
      121 ggaactgttg cgttgagtgg aacctggcaa caaggtaaca gagaaagtaa atcaatacgg
      181 cgaaatattg aatacacatg gattgaaaac tatgacacag cccatttaac atcaaagaaa
      241 gttaataagt ttgagattat ggatcaagtt gatgatgata gacttgtaca acttattcct
      301 gatttttatg tctttccaga aaaaagtgta agctataata tactaaagca aggtaagcat
      361 gcttttattt tgagcattgg taacagagca ataatgcatt gtgcaaggta aactaaaata
      421 gataacaaaa agatggaacc tcgttaatca taaaacaata aaattaaata ttctcgcagt
      481 atatggcagt ctaaagcatc aaagttttga tcaacatctt tcattttaga catctccttg
      541 caatgtaaaa tatcatgtat caacaacatc tggtgcaaat ccatgagtcg aactcgacat
      601 tcatcttagc tcgattatta ttccttcgta cagtcgatgt aaacaataca gaaagaggat
      661 tattaataac cagtttactc agtgaatcaa tagaggaaag gattaacgtt tctttaaaag
      721 aattaatttc atcatctgtt aaactaaact catcattgac agatcgtgag atataactgt
      781 ttttaacttt actctttacg ttgactttat tgacagaatt aacattcaca tatcttgaat
      841 ttaatgtcca tgatgttgtt tgcgtgagaa ccttctcagc attaatgaat tttttaacgg
      901 aatccttggt ttctttttcg agtccgaatt tacaatatca tgcatataga ccatttcatg
      961 aatctgcgaa aactcaatgt ccattgtata cctcacattt ttaccgtgac tcgatgttac
     1021 tgttcaataa tcaccttcca tcaatactaa aattaatacc cctaatgtgc cgataacaaa
     1081 tatagtcatt ctacgtaacg tctccataag gtgatatttg acattatcag aagctgcgaa
     1141 ttcggatttt gctctaatca aatgagagaa atgtaaaatg aagccacgaa atattaataa
     1201 tagcctatca ctgcaaccat tagttcctga tcaggagaac aaaaataaga aaaatgaaga
     1261 gaaatccgtt aatccagtta aaatcacaat ggggtctggt ttaaattata ttgaacaaga
     1321 atctcttgga ggaaaatatc taatacatga tttgtcaata aagatagcgg atatttctga
     1381 agagataatt cagcaagcaa tattatctgc tatgagcata ta
//
LOCUS       DAZUDJ010000275         1411 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.280, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000275 DAZUDJ010000000
VERSION     DAZUDJ010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1411
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.280"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..372
                     /locus_tag="ACHY1N_005401"
     CDS             <1..372
                     /locus_tag="ACHY1N_005401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail U family protein"
                     /protein_id="HFS4047493.1"
                     /translation="AVLDALELHEHGATLFDGRPVVFDEEDFPAVAVYLTDAEYTGEE
                     LDADTWRATLHIEVFLPAQVPDSELDSWMESRIYPAMSAIPALAGMITTMVQQGYDYR
                     RDDDMALWSSADLTYSITYEM"
     gene            380..1132
                     /locus_tag="ACHY1N_005402"
     CDS             380..1132
                     /locus_tag="ACHY1N_005402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047494.1"
                     /translation="MPTPNPLAPVKGAGTTLWVYTGKGDAYANPLSDDDWQRLAKVKD
                     LTPGEMTAESYDDNYLDDEDADWSATGQGQKSAGDTSFTLAWKPGEEGQKGLIGWFES
                     GDVRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSEITP
                     ATAIKVTPTSGTVEKGKTTTLTVSFEPESATDKTFRAVSADPSTGTIAVKDMVITVTG
                     VKAGKVSIPVISGNGQFATVAEVTVTEAGAAG"
     gene            1146..>1411
                     /locus_tag="ACHY1N_005403"
     CDS             1146..>1411
                     /locus_tag="ACHY1N_005403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HFS4047495.1"
                     /translation="MFLKTEQFEYNGVSVTLSELSALQRIEHLALLKRRAEQAESSGN
                     LQVSVEDLVRTGAFLVAMSLWHNHPQKTGSPSMNEAVMQIEQEVL"
BASE COUNT          345 a          322 c          437 g          307 t
ORIGIN      
        1 gcagtgctgg atgcactgga actgcatgaa cacggggcga cgctgtttga tggtcgcccc
       61 gttgtttttg acgaagagga ttttcccgcg gtcgcggttt atctgacgga tgcagagtat
      121 accggtgaag agctggatgc ggatacctgg cgggccacac tgcatattga agttttcctg
      181 cctgctcagg tgccggattc agagctggat tcgtggatgg agtcccggat ttatccggcg
      241 atgtccgcga tccctgcact ggcagggatg attaccacga tggttcagca gggctatgac
      301 tatcgtcgtg atgacgatat ggcgttatgg agctctgcag atttgactta ttccattaca
      361 tacgagatgt gaggacgata tgccaacacc aaatcccctg gcgccggtaa aaggtgccgg
      421 taccactctg tgggtttaca ccggcaaggg tgatgcttat gcaaacccgt tgtcagatga
      481 tgactggcag cgactggcta aggtgaagga tctgacgccg ggcgagatga cggcagaatc
      541 ctacgatgat aactacctgg atgatgaaga cgcggactgg agcgcgaccg ggcaggggca
      601 gaagtctgca ggagatacca gttttacgct ggcctggaaa ccgggagaag aaggtcagaa
      661 agggcttata ggctggtttg aaagcgggga tgtgcgggcc tataaaatcc gtttcccgaa
      721 cggcacggtg gatgtgttcc gtggctgggt cagcagtatc ggtaaggccg taacggcgaa
      781 ggaagtgatc acccgtacgg tgaaagtgac caacgtgggt aaaccttccg tggcggaaga
      841 acgcagcgaa attacgccgg ccactgcaat taaggtgaca ccgacatccg gtaccgtgga
      901 aaaaggaaaa acaaccaccc tgactgtttc ttttgagccg gaaagtgcaa ccgacaagac
      961 gttcagagcg gtttccgccg atccgtcaac gggaaccatt gctgtgaaag atatggtgat
     1021 cactgtgacg ggggttaagg ctggaaaagt gagtatcccc gtgatttccg gtaatggtca
     1081 gtttgccacg gtagctgaag tcaccgttac tgaagcaggc gctgcagggt aaacggaggt
     1141 catacatgtt tctgaaaaca gaacaatttg aatataacgg tgtgtctgtc acgctttccg
     1201 aattgtctgc gctgcagcgt attgagcatc ttgccctcct gaaacggcgt gcagaacagg
     1261 cagaatccag cggcaacctg caggtaagcg tggaagatct cgtcagaacc ggcgcgtttc
     1321 tggtggcgat gtccctgtgg cataaccatc cgcagaaaac ggggtcaccg tcaatgaatg
     1381 aggctgtgat gcagattgag caggaagtcc t
//
LOCUS       DAZUDJ010000276         1403 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.281, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000276 DAZUDJ010000000
VERSION     DAZUDJ010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1403
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.281"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..254
                     /locus_tag="ACHY1N_005404"
     CDS             <1..254
                     /locus_tag="ACHY1N_005404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003796 - lysozyme activity [Evidence
                     IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA];
                     GO_process: GO:0016998 - cell wall macromolecule catabolic
                     process [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="HFS4047496.1"
                     /translation="VPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRINAGDRKGACEA
                     IRWWIKDGGRDCRIRSNNCYGQVSRRDQESALACWGIDR"
     gene            547..678
                     /locus_tag="ACHY1N_005405"
     CDS             547..678
                     /locus_tag="ACHY1N_005405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047497.1"
                     /translation="MSDKLIMLAKILCVIVGISFSLMLVALFLSMGWMMLSSSGLLG"
     gene            901..1107
                     /locus_tag="ACHY1N_005406"
     CDS             901..1107
                     /locus_tag="ACHY1N_005406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rz1 family lipoprotein"
                     /protein_id="HFS4047498.1"
                     /translation="MRELKMKLCVLMLPLVVSACGSTPPAPVPCVKPPAPPAWAMMPP
                     SNSLRLLDETFSVSETESSATRQH"
     gene            1172..1396
                     /locus_tag="ACHY1N_005407"
     CDS             1172..1396
                     /locus_tag="ACHY1N_005407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047499.1"
                     /translation="MKKLLVTVKPFQGTIPFRILQRGRVLVEGSFSGKCTQLHSRTFQ
                     VNATNEELTVECTMNAAKCRMVSAALQPVC"
BASE COUNT          345 a          311 c          380 g          367 t
ORIGIN      
        1 aagtgccgct gaccgaaccc cagaaagcgg ggatcgcgtc attctgtccg tataacattg
       61 gccccggtaa gtgtttcccg tcgacgtttt ataaacgaat taatgcaggt gatcgaaaag
      121 gtgcctgcga agcgattcgc tggtggatta aggacggtgg cagagactgc cgtatccgct
      181 caaataattg ctacggtcag gtatcccggc gagatcagga aagtgcgctg gcgtgctggg
      241 gtatcgacag ataagcagaa tattttgctt aaaaatgacg ttggccaacg cgggcagata
      301 acacgaaatc ctgcgaactg gcaaaaccca agtgaataaa agtaaaaacc ccgtttgttg
      361 gttgcaaacg gggttttatg tttatggcag taagctatgg gaggctgcct tgattgattt
      421 tagcaaactg attagggagt tgcgactcat gattagtcaa ttaccaaact ggaaattttt
      481 gctggtctgg agcatccctt ttttatgggt agtatcccag tgaattgtgg caattaaggg
      541 gtagctatgt cagacaaact cataatgctg gcgaagatcc tctgtgtaat cgtcggcatt
      601 tcattttcac taatgctggt tgctcttttt ctttccatgg gctggatgat gttgtcttcg
      661 tcggggctgc tggggtgagc ataaaccgaa tgctttccgc gtttaccgtt attctgctgg
      721 tggtctgtgg tgcgcttagt ctggggctga atcattaccg cgataacgcc atcacctaca
      781 aagcgcagcg cgataaaaaa gccagtgagc tggatctggc aaacgcaacc attactgata
      841 tgcaggtgcg ccagcgcgat gttgctgcgc tcgatgcaaa atactcgagg gaattagccg
      901 atgcgagagc tgaaaatgaa actctgcgtg ctgatgttgc cgctggtcgt aagcgcctgc
      961 ggatcaacgc cacctgcccc ggtaccgtgc gtgaagccac cggcacctcc ggcgtgggca
     1021 atgatgccgc cgtcgaactc tctccggttg ctggacgaaa cgttctcggt atcagagacg
     1081 gaatcatcag cgaccaggca gcattgagaa tgcttcagga atatatccgc actcagtgta
     1141 ttaactagta tttttgttat tcggagaatg catgaagaaa ttattggtaa ccgtaaagcc
     1201 ttttcaggga acaattccgt tccgtatttt gcagcgtggt cgtgttcttg ttgaaggttc
     1261 gttcagtggt aaatgtacgc aattacactc ccggaccttt caggtgaatg ccacgaatga
     1321 agagctaacc gttgagtgta cgatgaatgc cgctaaatgc cgcatggtat ccgctgcatt
     1381 acagccagtg tgttgagcga cct
//
LOCUS       DAZUDJ010000277         1396 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.282, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000277 DAZUDJ010000000
VERSION     DAZUDJ010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1396
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.282"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1396
                     /locus_tag="ACHY1N_005408"
     CDS             <1..>1396
                     /locus_tag="ACHY1N_005408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
                     /protein_id="HFS4047500.1"
                     /translation="TLANHDNQIVFGTTNGMTISTGLEYGPDNEANTGGQWVQDGGTA
                     NKTTVTSGGLQRVNPGGSVSDTVISAGGGQSLQGRAVNTTLNGGEQWMHEGAIATGTV
                     INDKGWQVVKPGTVATDTVVNTGAEGGPDAENGDTGQFVRGDAVRTTINKNGRQIVRT
                     EGTTNTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASDTVVNSDGWQIVKNGGVA
                     GNTTVNQKGRLQVDAGGTATNVTLKQGGALVTSTAATVTGINRLGAFSVVEGKADNVV
                     LENGGRLDVLTGHTATNTRVDDGGTLDVRNGGTATTVSMGNGGVLLADSGAAVSGTRS
                     DGKAFSIGGGQADALMLEKGSSFTLNAGDMATDTTVNGGLFTARGGTLAGTTTLNNGA
                     ILTLSGKTVNNDTLTIREGDALLQGGSLTGNGSVEKSGSGTLTVSNTTLTQKAVNLNE
                     GTLTLNDSTVTTDV"
BASE COUNT          362 a          359 c          438 g          237 t
ORIGIN      
        1 gaacactggc aaatcatgac aaccagattg tcttcggtac gaccaacgga atgaccatca
       61 gtaccgggct ggagtatggg ccagataacg aggccaatac cggcgggcaa tgggtacagg
      121 atggcggaac agccaacaaa acgactgtca ccagtggtgg tcttcagaga gtgaaccccg
      181 gtggaagtgt ctcagacacg gttatcagtg ccggaggcgg acagagcctt cagggacggg
      241 cagtgaacac cacgctgaat ggtggcgaac agtggatgca tgagggggcg atagccacag
      301 gaaccgtcat taatgataag ggctggcagg tcgtcaagcc cggtacagtg gcaacggata
      361 ccgttgttaa taccggggcg gaagggggac cggatgcaga aaacggtgat accgggcagt
      421 ttgttcgcgg ggatgccgta cgcacaacca tcaataaaaa cggtcgccag attgtgagaa
      481 ctgaaggaac gacaaatacc actgtggttt atgccggcgg cgaccagact gtacatggtc
      541 acgcactgga taccacgctg aatgggggat accagtatgt gcacaacggc ggtacagcgt
      601 ctgacactgt tgtgaacagt gacggctggc agattgtcaa aaacgggggt gtggccggga
      661 ataccaccgt taatcagaag ggcagactgc aggtggacgc cggtggtaca gccacgaatg
      721 tcaccctgaa gcagggcggc gcactggtta ccagtacggc tgcaaccgtt accggcataa
      781 accgccttgg agcattctcg gttgtggagg gtaaagctga taatgtcgta ctggaaaatg
      841 gcggacgcct ggatgtgctg accggacaca cagccactaa tacccgcgtg gatgatggcg
      901 gaacgctgga tgtccgcaac ggtggtaccg ccaccaccgt atccatggga aatggcggtg
      961 tactgctggc cgattccggt gccgctgtca gtggtacccg gagcgacgga aaggcattca
     1021 gtatcggagg cggtcaggcg gatgccctga tgctggaaaa aggcagttca ttcacgctga
     1081 acgccggtga tatggccacg gataccacgg taaatggcgg actgttcacc gccaggggcg
     1141 gcacactggc gggcaccacc acgctgaata acggcgccat acttaccctt tccgggaaga
     1201 cggtgaacaa cgataccctg accatccgtg aaggcgatgc actcctgcag ggaggctctc
     1261 tcaccggtaa cggcagcgtg gaaaaatcag gaagtggcac actcactgtc agcaacacca
     1321 cactcaccca gaaagccgtc aacctgaatg aaggcacgct gacgctgaac gacagtaccg
     1381 tcaccacgga tgtcat
//
LOCUS       DAZUDJ010000278         1352 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.283, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000278 DAZUDJ010000000
VERSION     DAZUDJ010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.283"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..663
                     /locus_tag="ACHY1N_005409"
     CDS             <1..663
                     /locus_tag="ACHY1N_005409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc8 family transposase"
                     /protein_id="HFS4047501.1"
                     /translation="KGIHPQTHLACFSGVLQADAYAGFNELYRNGRITEAACWAHARR
                     KIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWL
                     RKKMKTLSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFL
                     FFGSDHGGEREALLYSLIGTCKLNDVDPESYLRHVLGVIADWPVNRVSELLPWRIALP
                     AE"
     gene            684..1034
                     /locus_tag="ACHY1N_005410"
                     /pseudo
     CDS             684..1034
                     /locus_tag="ACHY1N_005410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546148.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1169..>1352)
                     /locus_tag="ACHY1N_005411"
     CDS             complement(1169..>1352)
                     /locus_tag="ACHY1N_005411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047502.1"
                     /translation="SSAAHTNDRDLTMVDLFCCAGAIARQVPEAGSEVLSRVIASGRE
                     VLTRGLMAGDDVLTRE"
BASE COUNT          319 a          377 c          391 g          265 t
ORIGIN      
        1 aaaggcatcc atccgcagac tcatcttgct tgcttcagcg gtgtgctgca agcggatgcg
       61 tacgccgggt tcaacgagct gtatcgcaat ggtcggataa cggaagctgc ctgctgggct
      121 catgcccgcc gaaagatcca cgatgtgcac gtccgcatcc cgtcagcact gacggaagaa
      181 gccctggagc agatcggtca gttgtacgcc atagaggcgg atataagggg aatgccggca
      241 gagcagcggc ttgctgaacg tcagcgaaaa acgaaaccgc tgttgaaatc cctggaaagc
      301 tggttgcgta aaaagatgaa gaccctgtcg cgacactcag agttggcgaa ggcgttcgcg
      361 tacgcactta accagtggcc ggcactgacg tactatgcga acgatggctg ggtggaaatc
      421 gacaacaaca tcgctgaaaa tgccctgcga gcggtcagtc tgggtcgtaa aaacttcctg
      481 ttcttcggct ctgaccatgg tggtgagcgg gaagcgctac tgtacagcct gatcgggacg
      541 tgcaaactga atgacgtgga tccagaaagc taccttcgcc atgtgcttgg cgtcatagca
      601 gactggccgg tcaaccgggt cagcgaactg cttccgtggc gcatagcact gccagctgaa
      661 taacacatcc ccgtcaatac ggccctcgct gtacgcttac tccgggaagg gcattacaca
      721 aagccattgt ctatgcgctg tctcatcgcg tggaactaag ccgcttcctg gaagatggtg
      781 cggtgccgct ggataataat gtgtgtgaac gggccatcaa aaacgtggtc ctgggcagaa
      841 aatcgtggct gttcgccggt tcgcagatgg caggagaacg cgccgcgcaa ataatgagct
      901 tgctggaaac cgcgaaacgc aacggtctgg agccgcatgc ctggctgaca gacgtcctga
      961 tgcgtctgcc ggagtggccg gaggagcgac tggcagagtt gctgcctctt gagggattta
     1021 ccttctccgg gtgagtgata cctgccgtca ggtgttcgtg caccgggcca taacctgcag
     1081 tcgggagttg aactcctgac gacaggaaat gagccagacc agcaaccaca cgggctgaca
     1141 gcgaataaga acctgaatca gcccggagtc attcccgggt cagtacatca tcacctgcca
     1201 ttaatccccg agtcagtact tcgcggcctg acgcgatcac cctactcagt acttcagagc
     1261 ccgcctccgg tacctgtctg gcgatcgccc cagcgcaaca aaataaatca accatcgtca
     1321 gatcgcgatc attcgtatgc gccgccgatg ac
//
LOCUS       DAZUDJ010000279         1325 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.284, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000279 DAZUDJ010000000
VERSION     DAZUDJ010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1325
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.284"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..825
                     /locus_tag="ACHY1N_005412"
     CDS             <1..825
                     /locus_tag="ACHY1N_005412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HFS4047503.1"
                     /translation="VEQMQNQMDPVYTPARKIHLYHCDHRGLPLALVSTEGATEWCAE
                     YDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKG
                     GWNFYQYPLNPVQYIDSMGLASKYGHLNNGGYGARPNKPPTPDPSKLPDIAKQLRLPY
                     PIDQASSAPNVFKTFFRALSPYDYTLYCRKWVKPNLTCTPQDDSQYPGMDTKTASDYL
                     PQTNWPTTQLPPGYTCAEPYLFPDINKPDGPATAGIDDLGEILAKMKQRTSRGIRK"
     gene            822..>1325
                     /gene="ybfC"
                     /locus_tag="ACHY1N_005413"
     CDS             822..>1325
                     /gene="ybfC"
                     /locus_tag="ACHY1N_005413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YbfC"
                     /protein_id="HFS4047504.1"
                     /translation="MKRVLFFLLMIFVSFGVIADCEIQAKDHDCFTIFSKGTIFSAFP
                     VLNNKAMWRWYQNEDIGEYYWQTELGTCKNNKFTPSGARLLIRVGSLRLNENHAIKGT
                     LQELINTAEKTAFLGDRFRSYIRAGIYQKKSSDPVQLLAVLDNSIMVKYFKDEKPTYA
                     RMTAHLPN"
BASE COUNT          416 a          277 c          314 g          318 t
ORIGIN      
        1 gtggagcaga tgcaaaacca gatggacccg gtgtacacgc cggcgcgaaa aatccacctg
       61 taccactgcg accatcgcgg cctgccgctg gcgcttgtca gcacggaagg ggcaacagaa
      121 tggtgcgcag aatacgatga atggggcaac ctgctgaatg aagagaaccc gcatcagctg
      181 cagcagctta tccgcctgcc ggggcagcag tatgatgagg agtccggcct gtattacaac
      241 cgccaccgct attatgaccc gctgcagggg aggtatatca ctcaggatcc gattgggctg
      301 aaggggggat ggaattttta tcagtatccg ctgaatccgg ttcagtatat agattcaatg
      361 ggactggcat caaaatatgg acacttaaat aatggcggat atggagcgag acccaacaaa
      421 ccgcctacgc ccgatccaag taaattgccg gacatagcga aacaattaag actgccatat
      481 cctattgacc aggccagtag tgcgcctaat gttttcaaaa cattcttcag agcattaagc
      541 ccttacgact acacactgta ttgcaggaag tgggtaaaac caaatctgac ttgtacgcca
      601 caggatgatt cccagtatcc agggatggat acaaagacag caagtgatta cctgccacag
      661 acaaattggc caacaactca attaccacca ggatatactt gtgcagaacc ctatttattc
      721 ccagacatta ataaacccga tgggccagca acagcaggga tagatgattt gggtgaaatt
      781 ttagctaaga tgaaacagag aacatcgaga ggaataagaa aatgaaaaga gttttgttct
      841 ttttgctgat gatatttgtt agttttggtg ttatagctga ttgcgaaata caagctaaag
      901 atcatgattg ttttactatt ttctctaagg gtactatttt ttccgcgttt cctgtcttaa
      961 ataataaagc catgtggaga tggtatcaga atgaggacat cggtgagtat tattggcaaa
     1021 cagaactggg tacatgtaaa aataataaat tcacaccaag cggggcgaga ctcttaattc
     1081 gcgtcgggtc actacgcctt aatgaaaatc atgccatcaa aggaacgttg caggagttga
     1141 taaatacagc agaaaaaacg gcgtttctcg gcgatcggtt tagaagttat ataagagcgg
     1201 gtatctatca aaaaaagagc agtgatccag ttcagttgtt ggcagtcctt gataattcaa
     1261 tcatggtaaa atattttaaa gatgagaaac caacttatgc tcgaatgaca gcacatctcc
     1321 cgaac
//
LOCUS       DAZUDJ010000280         1305 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.285, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000280 DAZUDJ010000000
VERSION     DAZUDJ010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1305
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.285"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(49..423)
                     /gene="gpFI"
                     /locus_tag="ACHY1N_005414"
     CDS             complement(49..423)
                     /gene="gpFI"
                     /locus_tag="ACHY1N_005414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HFS4047505.1"
                     /translation="MATKEQNLKRLDELALILGREPDISGSAAEIAQRVAEWEEEIQS
                     SGEDVQVGDTVIRERETAAHDVREDTSGALTRIRVLTCLHLCGIDGETGESVEIADVG
                     RVILIMSSDAKTHVDGGMAVYA"
     gene            complement(475..>1305)
                     /locus_tag="ACHY1N_005415"
     CDS             complement(475..>1305)
                     /locus_tag="ACHY1N_005415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HFS4047506.1"
                     /translation="GGETRVLRPGYVKPKHEFNYQQAVERLPGEDPAQLNDPAYRRLR
                     IITDNLKQEEHAIVQVEEIQAVNAVLYGKYTMEGDQFEKIEVDFGRSTKNNITQGSGK
                     EWSKQDRDTFDPTHDLDLYCDQASGLVNIAIMDGTVWRLLNGFKLFREKLDTRRGSNS
                     QLETAVKDLGAVVSFKGYYGDLAIVVAKTSYIAEDGIEKRYLPEGMLVLGNTAADGIR
                     CYGAIQDAQALSEGVVASSRYPKHWLTVGDPAREFTMTQSAPLMVLPDPDEFVVVQVK
                     "
BASE COUNT          307 a          408 c          284 g          306 t
ORIGIN      
        1 atcgtgctgt ccaccccggc aagggcagca tcaaaggcat tctgaaaatc acgcataaac
       61 agccattccg ccatcaacgt gtgtttttgc atctgaggac ataatcagaa tcacccgacc
      121 aacatccgca atctcaacgg attcccctgt ttcaccatca atgccacaga gatggaggca
      181 ggtcagaact ctgatgcgcg ttaacgcacc ggatgtatcc tcacgaacat catgagccgc
      241 ggtttcccgc tcccggatca ccgtatcccc aacctgaaca tcctcgccgg atgactgtat
      301 ttcctcttcc cattccgcca cccgctgcgc tatctctgcg gcactcccgg atatatccgg
      361 ctcacgcccc agaatcaggg ccagttcatc aagccgtttc agattttgct ctttcgttgc
      421 catatcagcc ccctgtgaaa aaagacacgg gggcatttcg cccccgctca cggattattt
      481 cacctgtacc accacaaact catccgggtc cggcaacacc atcagcggcg cggactgcgt
      541 catggtaaat tcacgggcgg gatcccccac cgtcagccag tgtttcggat aacgggaaga
      601 ggccaccaca ccttcggaca acgcctgcgc atcctgaatg gcaccgtaac aacggatccc
      661 atctgcagca gtattcccca gaaccagcat gccctccggc agataacgtt tttcgatacc
      721 gtcttctgct atataagacg ttttcgccac cacaatggcc agatcgccgt aatacccctt
      781 gaaggacacc actgcgccca gatctttcac tgccgtttcg agttgagaat ttgaaccgcg
      841 acgggtatcc agtttttcgc ggaacagctt aaaaccattc agaagacgcc agacggtacc
      901 gtccataatg gcaatattca caagaccgct ggcctggtcg cagtagaggt caagatcatg
      961 tgtaggatcg aacgtgtcac gatcctgttt tgaccactcc ttaccactac cctgagtgat
     1021 gttattcttc gtcgacctgc caaaatcgac ctcaattttc tcgaactggt ctccttccat
     1081 cgtatatttg ccatacaaca cagcatttac cgcctgtatt tcttccacct ggacaatcgc
     1141 gtgctcttcc tgtttgaggt tatcggtaat gatacgcaga cggcggtaag ccggatcgtt
     1201 cagttgagcc ggatcttcac caggaaggcg ctcaaccgcc tgctggtaat taaattcgtg
     1261 tttcggcttg acgtagcccg gacgtaacac gcgggtttca ccacc
//
LOCUS       DAZUDJ010000281         1300 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.286, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000281 DAZUDJ010000000
VERSION     DAZUDJ010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1300
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.286"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1300
                     /locus_tag="ACHY1N_005416"
     CDS             <1..>1300
                     /locus_tag="ACHY1N_005416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin B"
                     /protein_id="HFS4047507.1"
                     /translation="SRVFFHGWDNKSIQYVTEINKDLIKDINLLLTSSNVDVKLLIKL
                     DRELYAISSKIENPLALRSIRTLQLQLTNYVTSNTFEPENTINFIYDFYSKKQNDLLS
                     AIKLFSRNDVETKIIVWYNSTMEKNVFLREVISCVLWTKKVDSYIKENKKHLSTEDAE
                     ALRDYAKLKIKELFSMLDDDGYKRIITTNSYIKERDKLSGIIHNIENSIISGHESSDI
                     IRSHQHEWGDLSTVEQFKKFEFYVKSELSFSKSIFDDIKTKYITDPETKRNALYHQLD
                     SDIKERIAFLDISHYAYPGSLLEKLQLSGYVFSDINIIAEYLLSSYGISGHYSHGVVY
                     PAPSDKLFELLRRHTNSNSDWIEKIIPYVYDILSGNVSSFLHPPLSEEQKKILSDIKL
                     EISESVSEQYFMKLTEQKSSVIGIKYSVDFDRYNENLFLSL"
BASE COUNT          497 a          187 c          201 g          415 t
ORIGIN      
        1 tcgcgagttt tttttcatgg atgggataat aaaagcatac aatatgttac tgagattaat
       61 aaagacctta ttaaagatat aaatttattg ttaacatcgt ctaatgttga tgttaaactt
      121 ttaataaagc tagatcgtga attatatgca ataagcagca aaatagagaa tccgttagcc
      181 ttgcgctcta taaggacttt acagctgcaa ttaactaatt atgtaacctc aaacacattt
      241 gaacctgaaa atacaattaa ttttatttat gatttttata gtaaaaaaca aaatgattta
      301 cttagcgcaa ttaagttatt ttcgcgtaat gatgtcgaga caaaaatcat tgtttggtac
      361 aattcaacaa tggaaaaaaa tgtattcctc cgagaggtta tatcatgtgt tctatggact
      421 aaaaaagtag actcttatat aaaagaaaac aaaaaacact tatctacgga agatgctgaa
      481 gctttaagag attatgcaaa attaaaaata aaagaactat tttcgatgtt ggatgatgat
      541 ggttataaaa gaatcataac aacaaattca tatattaaag agagggataa actatcaggc
      601 attatacaca acatcgaaaa ttctattata tcaggtcatg aatcatctga tataatacga
      661 agccatcaac atgagtgggg agatttatca acggtagagc aatttaaaaa atttgaattt
      721 tatgttaaaa gtgagttatc attttccaag tcaatttttg atgatataaa aaccaaatat
      781 ataacagatc ccgaaacaaa acgaaacgca ctttaccatc aattagatag tgatatcaaa
      841 gagcgaatag cctttctcga catatcccac tacgcatatc caggtagttt attagaaaaa
      901 ttacagttaa gcggctacgt tttttctgac atcaacataa ttgcagaata cttattgtct
      961 agttacggaa tttctgggca ttattctcac ggcgtggtat acccagctcc atctgataaa
     1021 ttatttgagt tattaagaag acatacaaat tccaattctg attggataga aaaaataatc
     1081 ccatatgttt atgatatctt atcaggtaat gtgtccagct tcttgcaccc tcccttatca
     1141 gaagaacaga aaaaaatatt gagtgatata aaattagaaa ttagtgaatc tgtatcagaa
     1201 cagtatttca tgaagttgac agaacaaaaa tcatcagtta ttggcattaa atactctgtt
     1261 gattttgata gatacaatga gaatttattt ttgtctttac
//
LOCUS       DAZUDJ010000282         1297 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.287, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000282 DAZUDJ010000000
VERSION     DAZUDJ010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.287"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(528..1097)
                     /locus_tag="ACHY1N_005417"
     CDS             complement(528..1097)
                     /locus_tag="ACHY1N_005417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HFS4047508.1"
                     /translation="MSEITVSRPEVVNENTDVICSTSVRYRSLEYDNFPEISEANILS
                     TFEQLHQNKDEVFERGVINVFKGLSWDYKTNSPCKFGSKIIVNNLVRWDQWGFHLISG
                     MQADRLADLERMLHLLSGKPIPDNRGNITINLDDHIQSVQGKGRYEDEMFIIKYFKKG
                     SAHITFKRLELIDRINDIIARHFPSVLSA"
     gene            complement(1194..>1297)
                     /locus_tag="ACHY1N_005418"
     CDS             complement(1194..>1297)
                     /locus_tag="ACHY1N_005418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HFS4047509.1"
                     /translation="EDKTDSAALLPCIEQAREDIRTLRQLQLQHQNR"
BASE COUNT          341 a          278 c          307 g          371 t
ORIGIN      
        1 aaggaaagaa gagtctgttg caggtggacg gagtggtgaa gagccccatg tcaatggcgt
       61 atcaggtttt cccgcttgtt attgaagatt ttcccacctt attctccgcg acaaaatcac
      121 gttaaaacct gcggattaag gcgaaatgat aactctcctg tttccccgtg ttttctactt
      181 cattatgaat gttctgagaa aagggaaccg tagaaagacc gtagtagtag agtaaggaca
      241 aggcacacat cataggatgt tggggtgtct aaaagtaacg aacatcggcg aaaatagtga
      301 gaaatacaac aaacaaataa cgtattgcaa cgaccagaaa tctaccgtag ccagaaaagc
      361 aaaaagcccc gcttttcagc gaggccttat gaatttggtg ccggactcgg aatcgaagaa
      421 tgcttctatc atgttgatat tagtttattt tgtttggttt ggtgaaatat gtaccctctt
      481 ttgtacccgc agtccctttt gatatcgaaa gggaatcaaa ctcggggtca ggctgagagc
      541 acagaaggaa agtgcctggc tattatatcg ttaattctgt caatcagctc cagccttttg
      601 aaagtgatgt gtgcagatcc cttcttaaag tatttaatga tgaacatctc atcttcatag
      661 cgtcctttac cctgaacgga ctgtatgtgg tcatccagat taatggtgat attccctcgg
      721 ttgtcgggga tcggtttacc gctgagcaga tgcaacattc tttccaggtc agccaggcga
      781 tctgcctgca ttccactgat aagatgaaat ccccactggt cccatctcac cagattgttg
      841 acgataattt tactgccaaa tttacagggt gagttggttt tgtaatccca gctcagccct
      901 ttgaagacgt tgatcactcc ccgttcaaac acttcatctt tgttctggtg cagttgttca
      961 aatgtgctca gaatgttcgc ttcgctgatt tccggaaaat tatcatattc cagtgacctg
     1021 tacctgactg aggtggagca gataacgtcc gtattctcgt tgaccacttc cggacgggag
     1081 actgtgattt cagacataat cgatattcct ttttgcagat aaatgaaaac gccagccgtg
     1141 ttcaggctgg cgtcagtgga atgaagtctg gtgagtgaga tgatgagtga gactcaccgg
     1201 ttctggtgct gaagctgcag ttggcgcagg gtacggatat cctctctggc ctgttcgata
     1261 cagggcaaca gtgctgctga atccgtttta tcctcat
//
LOCUS       DAZUDJ010000283         1287 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.288, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000283 DAZUDJ010000000
VERSION     DAZUDJ010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1287
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.288"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            71..>1287
                     /gene="nleA"
                     /locus_tag="ACHY1N_005419"
     CDS             71..>1287
                     /gene="nleA"
                     /locus_tag="ACHY1N_005419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector NleA"
                     /protein_id="HFS4047510.1"
                     /translation="MNVQPNVHTGLTPPLHLAHPPHPAPNQIPESELPPGCETGFVVN
                     IPEDIQQHTPECGETTALLGLIRDKGLLSGLDAYLAPHLEEGSAGKKALDMFGLFNVT
                     QMALEIPSTVPGISGKYGVQMNIVKPDIHPTTGNYFLQLFPLHDEVGINFGALPGPLQ
                     KFLSQNPNPWFGVTAQVVRNHGIELPIVKTDNGWKLVGETPLTPEGPKANYTEEWVIR
                     PGEFDLKYGSTPLQSTLGLEFGAHFKWDLDNPNTKYAVLTNALANAAGAAGGYTLSQY
                     TGTDAMLSPHVGSMAGQALGHAVQCYTPGLKPDTILWWAGTTLGLADLNKAETGEGRF
                     TDYPRIWWHAREGAIFPNKEDIARATGADIRAMEEGIPVGQRHPNPEDVVIDIESNGL
                     PHHNPSNHVDIFD"
BASE COUNT          394 a          272 c          284 g          337 t
ORIGIN      
        1 atatgtgaca ctaatagtat caatggattg atattattaa tggatataaa ctatgtaata
       61 aggatttatt atgaatgttc aaccaaatgt gcacactgga ttaacccccc ccttacatct
      121 tgcacaccca ccacatcctg cgccaaatca gataccggaa tcagaattgc cacctggatg
      181 tgagactgga tttgttgtta atattccaga ggatatacag caacacactc cggaatgcgg
      241 tgaaacaaca gctctgttgg gtttaataag agataaaggt ctgctctcag ggttagacgc
      301 atatcttgct cctcaccttg aagaaggctc agcaggaaaa aaagcattgg atatgtttgg
      361 tttattcaat gttactcaga tggcattaga aatacccagc accgttcctg gtatctctgg
      421 taaatatggt gttcagatga acattgtaaa accagatatt caccccacaa ccgggaatta
      481 ttttttacag ttattccccc tacatgatga ggtgggaata aacttcggtg cgctcccagg
      541 accactccag aagtttctct ctcaaaatcc caatccatgg tttggagtaa cagctcaagt
      601 tgttcgtaac cacggcatag aactacctat agtcaaaaca gataatggat ggaaactagt
      661 tggagaaaca ccacttacac ctgaagggcc taaagcaaat tatacggaag aatgggtcat
      721 cagacctggt gagtttgact taaagtatgg cagcactccg ttgcagagca ctttaggttt
      781 agaatttgga gctcatttta aatgggattt agataatcct aataccaaat atgccgttct
      841 taccaatgca cttgcgaatg cagctggtgc tgcaggggga tatactctat ctcaatatac
      901 aggaacagac gcaatgctga gcccccatgt tggctcgatg gccggacagg ctttggggca
      961 tgctgtacaa tgctacactc caggattaaa gccagacact attttatggt gggcaggtac
     1021 gactctgggg ctggcagatt taaacaaagc cgagacaggt gaaggcagat tcactgacta
     1081 tcctcgtata tggtggcacg caagagaagg tgccatcttc cctaataaag aagatattgc
     1141 ccgtgcaaca ggggctgata tacgagctat ggaagaaggt atccctgttg gacagcggca
     1201 tccaaatcca gaggatgtgg taatcgatat cgaaagcaat ggcttaccac atcataatcc
     1261 atcaaatcat gttgatatct ttgatat
//
LOCUS       DAZUDJ010000284         1251 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.289, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000284 DAZUDJ010000000
VERSION     DAZUDJ010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1251
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.289"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            183..1163
                     /locus_tag="ACHY1N_005420"
     CDS             183..1163
                     /locus_tag="ACHY1N_005420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS621 family transposase"
                     /protein_id="HFS4047511.1"
                     /translation="MEHELHYIGIDTAKEKLDVDVLRPDGRHRTKKFANTTKGHDELV
                     SWLKGHKIDHAHICIEATGTYMEPVAECLYDAGYIVSVINPALGKAFAQSEGLRNKTD
                     TVDARMLAEFCRQKRPAAWEAPHPLERALRALVVRHQALTDMHTQELNRTETAREVQR
                     PSIDAHLLWLEAELKRLEKQIKDLTDDDPDMKHRRKLLESIPGIGEKTSAVLLAYIGL
                     KDRFAHARQFAAFAGLTPRRYESGSSVRGASRMSKAGHVSLRRALYMPAMVATSKTEW
                     GRAFRDRLAANGKKGKVILGAMMRKLAQVAYGVLKSGVPFDASRHNPVAA"
BASE COUNT          306 a          309 c          371 g          265 t
ORIGIN      
        1 cctccagtgc agagaaaatc ggccagtttt ctctgcctgc agtccgcatg ccgtatcggg
       61 ccttgggttc taacctgttg cgtagattta tgcagcggac tgcctttctc ccaaagtgat
      121 aaaccggaca gtatcatgga ccggttttcc cggtaatccg tatttgcaag gttggtttca
      181 ctatggaaca tgaacttcat tatatcggta tcgacaccgc taaagagaaa ctggatgtcg
      241 atgtgttgcg tcctgatggt cgtcatcgca ccaaaaaatt cgctaacacc actaaagggc
      301 acgatgagct ggtgagctgg ctgaaaggtc acaagattga ccatgcgcat atctgcatcg
      361 aagcgaccgg cacctatatg gaacctgtcg ctgagtgcct ttacgatgct ggctacatag
      421 tgtcagtcat taatcctgcg ctgggtaaag ctttcgctca gagtgaagga ctgcgtaaca
      481 agactgatac cgtggatgcg cgcatgctgg cagagttctg tcgtcagaag cgccctgcag
      541 cctgggaagc gcctcacccg cttgaacgcg cgttgcgtgc cctggtagtc cgccaccagg
      601 cgctgacaga tatgcacacg caggaactga atcgcactga aacggcgcgg gaagtccaga
      661 gaccgagcat tgatgctcac cttctgtggc ttgaagcaga gctgaagcgt cttgagaagc
      721 agataaaaga cctgacagac gatgatccgg atatgaaaca ccgcaggaaa ctgctggaaa
      781 gcatcccggg tatcggagag aaaacatctg cggtattgct ggcttatatc ggtctgaagg
      841 accgcttcgc ccatgccaga cagttcgccg cttttgcggg tctgacacca cggcgttatg
      901 aatcaggtag cagtgtgaga ggggcgagcc ggatgagtaa ggccggacat gtgtcgcttc
      961 gcagggcgtt gtatatgccc gcaatggtag ccaccagtaa gactgagtgg ggacgggcgt
     1021 tccgcgaccg tctggcggct aatggcaaga aaggaaaggt gattctcggc gcgatgatgc
     1081 gcaagctggc acaggtggcg tatggagtgc tgaagtcagg cgtgccgttc gatgcgtcac
     1141 ggcataatcc ggtagcggcg taaaaatcgc ggaagggatg aaaaaaacag cgcctgacgg
     1201 cgctgtgtct ggcatgcctg caatccggga aaccggacca ggaaaaaact t
//
LOCUS       DAZUDJ010000285         1248 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.290, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000285 DAZUDJ010000000
VERSION     DAZUDJ010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.290"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1248
                     /locus_tag="ACHY1N_005421"
     CDS             <1..>1248
                     /locus_tag="ACHY1N_005421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001239084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="TcdA/TcdB catalytic glycosyltransferase
                     domain-containing protein"
                     /protein_id="HFS4047512.1"
                     /translation="VTEINDELRINYLKNVIKLSDDDIGNYQKTINDNKDRVKKLILD
                     LQKQFGENRISIKDVNSLTSLSKSENNHNYQTEMLLRWNYPAASDLLRMYILKEHGGI
                     YTDTDMMPAYSKQVIFKIMMQTNGDNRFLEDLKLRRAISDGVLRYVNNQNIDEVNYNE
                     ISDADKNIIKKILTEISKMPEDSIFTKINTRIPRDTMPILRRYHLWPDGWNIRGLNGF
                     MLSHKGSEVIDAVIAGQNQAYRELRRIRDNIHSEIYFKQTDELSSLPDTDKIGGILVK
                     KYLSGSLFSKFRQDTIIPEALSTLQISGPDLIQRKMLQFFRSRGVLGEEFINERKLSD
                     KAYIGVYKTTGTGKYDWLNPESIGVNDVTPADESTWCIGKGRCVDDFLFKDVSKLKTE
                     NLPELFLTKIDTDTFFSQWSTKT"
BASE COUNT          461 a          204 c          234 g          349 t
ORIGIN      
        1 gtgttacaga gattaatgat gagttacgaa taaactacct taaaaatgta ataaaactgt
       61 cagacgatga cattggtaat tatcagaaaa caattaacga caataaagat agagtaaaaa
      121 aactaattct tgatttacag aaacaatttg gtgaaaaccg tatttcaatt aaagatgtta
      181 actctttaac ctctctttca aaatcagaaa ataatcacaa ttatcaaact gaaatgttgc
      241 ttcgatggaa ctatcctgcc gcctcagacc tgctcaggat gtatatcctt aaagagcatg
      301 gtggtattta tacagacaca gacatgatgc ctgcatactc taaacaagta atttttaaaa
      361 ttatgatgca gacaaacgga gataatcgtt tcttggaaga tttgaaacta cgtcgtgcaa
      421 tatctgatgg tgtattaaga tatgttaata accaaaatat tgatgaagtt aactataatg
      481 aaatcagtga tgcagataaa aacattatca agaagatatt aacagaaata tctaaaatgc
      541 cagaagatag catttttact aagatcaata caaggattcc tcgagacaca atgcccatcc
      601 ttcgtcgtta tcacctatgg cctgatggat ggaatattcg tgggctcaat ggattcatgc
      661 tatcacataa aggtagtgaa gtgattgatg ctgttatcgc aggccagaat caggcttaca
      721 gggaactaag aagaataaga gataatattc atagtgaaat atacttcaaa caaactgatg
      781 aattgtcctc acttccagat acagacaaaa ttggagggat tctggtaaaa aaataccttt
      841 caggaagtct tttttcaaaa ttcagacaag atactattat cccggaggca ttgagcaccc
      901 tccagatatc aggtcctgac ttgattcaaa gaaagatgtt gcaatttttc aggagtagag
      961 gggtgttagg tgaagagttc attaatgaaa gaaaactgag tgataaagct tatattggtg
     1021 tctacaaaac aactggcaca gggaaatatg actggttaaa ccctgaatcg atcggcgtta
     1081 atgatgtcac gcccgcagat gaaagtacct ggtgtatagg aaaaggccgg tgtgttgatg
     1141 acttcctgtt caaagatgtt tcaaaactaa aaacagaaaa tcttccagaa ttattcttaa
     1201 caaaaataga tactgatacg tttttctctc agtggtcaac caaaacca
//
LOCUS       DAZUDJ010000286         1205 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.291, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000286 DAZUDJ010000000
VERSION     DAZUDJ010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1205
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.291"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            298..867
                     /locus_tag="ACHY1N_005422"
     CDS             298..867
                     /locus_tag="ACHY1N_005422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor N-terminal domain-containing
                     protein"
                     /protein_id="HFS4047513.1"
                     /translation="MNMMTVPFHGDSLYVVNHNGEPYVPMKPVVAGMGLAWQSQLAKL
                     RQRFASTITEIVMVAEDGKRRNMVSLPLRKLAGWLQTINPNKVKPEIRGKVIQYQEEC
                     DDVLYEYWTKGFVVNPRRMSVMEELNQACADMKRDKNIASVFATGLNEWKQVKSAHVS
                     KIRTLINEANLLIDFVLADTDKGKITKAD"
     gene            867..1016
                     /locus_tag="ACHY1N_005423"
     CDS             867..1016
                     /locus_tag="ACHY1N_005423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047514.1"
                     /translation="MEWWLMISDKLITLAKILCVIVGISFLVILVAIFFSTAWRVLTL
                     SGLVG"
     gene            1024..>1205
                     /locus_tag="ACHY1N_005424"
     CDS             1024..>1205
                     /locus_tag="ACHY1N_005424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310766.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HFS4047515.1"
                     /translation="MNRVLCVVIIVLLVACGALSLGLNHYRDNAITYKEQRDKKVSEL
                     ELANATITDMQQRQRDV"
BASE COUNT          332 a          247 c          322 g          304 t
ORIGIN      
        1 cgtgctgggg aatcgacaga taagcagaat attttgctga aaaatgacgt tggccagcgc
       61 gggcggataa cacgaaatcc tgcgaactgg caaaatgtaa gtgaataaag ttaggcagat
      121 tatttcacgc agaggcaccg taatggtgcc tttgtcattt ctgcgcttcg cacaagcgta
      181 aataaaccaa agaacctttc aggatgagcc ctggtggata accggcagtg gtctggttaa
      241 ccctctttgg gctggttatt cctgtgcgca gggttcatca ctaaaaggaa ataaccgatg
      301 aatatgatga ccgtgccgtt tcacggcgat tctctttatg tggttaacca taacggcgaa
      361 ccatacgttc ccatgaaacc tgtcgttgcg gggatggggc tggcctggca atcacagttg
      421 gctaagttaa gacagcgttt tgcgtcaact ataacggaaa tcgttatggt tgctgaggat
      481 gggaaacgac gcaatatggt gtccctgccg cttcgaaaac ttgcaggctg gttacaaacc
      541 atcaatccca acaaagtaaa acccgaaatc cgcggcaagg taatccagta tcaggaagag
      601 tgtgacgatg ttctctatga atactggacg aagggttttg tcgttaatcc ccgtcgaatg
      661 agtgtgatgg aagaactcaa tcaggcttgc gctgacatga aacgggataa aaacattgcc
      721 agtgtgtttg ctaccgggct gaatgagtgg aaacaggtta aatccgcgca tgtatcaaaa
      781 atccgcacat tgataaacga agcgaatctg ctgattgatt ttgtcctggc tgatacagac
      841 aaagggaaaa taacaaaggc ggattgatgg agtggtggct aatgatatcg gataaactca
      901 taacgctggc gaagatcctc tgtgtaatcg tcggcatttc atttttagtc attctggttg
      961 ccattttctt ttccaccgct tggcgagtcc tgacgttatc gggactggtg gggtgaaaga
     1021 gagatgaacc gtgttctgtg tgtggtgatt attgtcctgc tggtagcctg tggtgcactt
     1081 agtctggggc tgaatcatta ccgcgataac gccataacct acaaagagca gcgcgataaa
     1141 aaagtcagtg agctggagct ggcaaatgca accattactg atatgcagca gcgccagcgt
     1201 gatgt
//
LOCUS       DAZUDJ010000287         1188 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.292, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000287 DAZUDJ010000000
VERSION     DAZUDJ010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.292"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..269)
                     /locus_tag="ACHY1N_005425"
     CDS             complement(<1..269)
                     /locus_tag="ACHY1N_005425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HFS4047516.1"
                     /translation="MQRRQNNILTKTSLLSRALSVPCCDMFRRGSPWICYLSLSVFSG
                     FFIPAFSSPAAMLSPGDRSAIQQQQQQLLDENQHQRDALERSAPLT"
     gene            complement(368..>1188)
                     /locus_tag="ACHY1N_005426"
     CDS             complement(368..>1188)
                     /locus_tag="ACHY1N_005426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4047517.1"
                     /translation="VILRRTDDWMDGRRSRHTDDTDVLLRIHHVIGELPTYGYRRVWA
                     LLRRQAELDGMPAINAKRVYRIMRQNALLLERKPAVPPSKRAHTGRVAVKESNQRWCS
                     DGFEFRCDNGEKLRVTFALDCCDREALHWAVTTGGFNSETVQDVMLGAVERRFGNELP
                     ASPVEWLTDNGSCYRANETRQFARMLGLEPKSTAVRSPESNGIAESFVKTIKRDYISV
                     MPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQQASNGLSDNRCLEI"
BASE COUNT          270 a          341 c          296 g          281 t
ORIGIN      
        1 gtcagcggcg cactgcgctc cagcgcatca cgctgatgct ggttttcatc cagcaactgc
       61 tgctgttgct gctgaattgc actgcggtca cccggagaca gcatggctgc cggagacgaa
      121 aatgcgggga taaaaaaacc agaaaaaacg gagagggaga gatagcatat ccacggagag
      181 ccacgccgga acatatcaca acaggggaca gacaacgcac gggataaaag ggacgttttc
      241 gtcagaatgt tgttctgccg gcgctgcatg ttctccccgt attctggcct gtgtgatgcc
      301 agtgtaaatt catgtcaaaa agtgtcagcg agaaaattta cacctgaaaa agtctgtgga
      361 tttgccccta tatttccaga cacctgttat cacttaaccc attactggct tgctgccgta
      421 gatattcccg tggcgagcga taacccagtg cactatgcgg atgccattcg ttataatgct
      481 cgaacgcctc tgcaaggttc tttgctgccg ttaacccgtc tggtttgggc atgacactga
      541 tgtagtcacg ctttatcgtt ttcacgaagc tctctgctat gccgttactc tccggactcc
      601 gcaccgccgt gctcttcggt tcaagcccca acatccgggc aaactgccgt gtttcattag
      661 cccggtagca tgaaccatta tccgtcagcc actctactgg agacgccgga agctcgttgc
      721 cgaagcggcg ttccaccgct cccagcatga cgtcctgtac tgtttcactg ttgaagccgc
      781 ccgtagtgac cgcccagtgc agtgcctcac ggtcacagca gtccagcgcg aacgtgactc
      841 gcagtttttc tccgttatca cagcggaact cgaacccgtc agagcaccat cgctgattac
      901 tttctttcac agccactctg cctgtatgtg cccgtttcga tggcggtaca gcaggttttc
      961 gctcaagcaa cagcgcattc tggcgcatga tccggtaaac acgtttggca ttgatcgcag
     1021 gcataccatc aagttctgcc tgtctgcgaa gcagcgccca tacccgacga taaccatacg
     1081 tgggcagctc tccgataaca tggtgtatac ggagaagcac atccgtatca tcagtgtgac
     1141 gactgcggcg gccatccatc cagtcatcgg ttcgtctgag aatgacgt
//
LOCUS       DAZUDJ010000288         1168 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.293, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000288 DAZUDJ010000000
VERSION     DAZUDJ010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1168
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.293"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            216..425
                     /locus_tag="ACHY1N_005427"
     CDS             216..425
                     /locus_tag="ACHY1N_005427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047518.1"
                     /translation="MPNKKRNPLIEKQIECLVNQLRQSGLLKTHSELRLTESAFDDKL
                     NNVLYNGIIDFNRSVGRRGPAGVSL"
     gene            complement(426..1064)
                     /locus_tag="ACHY1N_005428"
     CDS             complement(426..1064)
                     /locus_tag="ACHY1N_005428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047519.1"
                     /translation="MEFKDLPPSIQEIAAHTLRHRLNELELESVTKKDTDNMARNVRD
                     AFTGLYFCASINKHDSESVANKIAETTAQNINTKPTEEEIDQFAHDAGLKNKKEKSPY
                     AGNMFVYDNLIRIRGEIPAEYLARVHQALLKNLETELFDGNTNGFFMVSGLDKDWDAE
                     KRWNVATWLFSNRAAALEASACICGLFLTDHKYNLDVYSYIYAEHGPLWIDW"
     gene            complement(1076..>1168)
                     /locus_tag="ACHY1N_005429"
     CDS             complement(1076..>1168)
                     /locus_tag="ACHY1N_005429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HFS4047520.1"
                     /translation="DGTFTAMTYTKSKTFKTEAGAHRWLARNSD"
BASE COUNT          314 a          267 c          231 g          356 t
ORIGIN      
        1 tgccacaacc ggaagcgcac gttcgaagaa atctaacgac aagccttcta agggaaagag
       61 cttcgccgta cgctttcgcg ttatgccctg acttttcagg gaaatatcct ttcagtaaac
      121 tgtcagtacc ggattcttat ccgtgtccgg cgcacgacca cacgtgacag cgtgttggtc
      181 tccattttta acccagaacc tcaatggagg ataaaatgcc aaacaaaaaa agaaatccgc
      241 ttattgaaaa acagattgaa tgcctggtaa atcaactcag gcaatcaggg ttattaaaaa
      301 ctcattcaga gttgaggctc acagaatcag cattcgacga taaattaaat aatgtccttt
      361 ataatggcat tattgatttt aatcgttctg ttggtcgccg cggccctgct ggtgtttcct
      421 tataattacc agtcaatcca gagtggaccg tgttcagcgt aaatataact gtacacatcc
      481 agattatatt tgtggtctgt taagaacagg ccgcaaatac atgccgaagc ttccagtgca
      541 gcggctctgt tactgaataa ccatgtagca acattccagc gtttttctgc atcccagtct
      601 ttatcaaggc ctgataccat gaagaaaccg ttagtgttgc catcaaataa ttctgtttcc
      661 aaatttttaa gcaatgcctg atggactctt gccaggtatt ccgccggaat ttcgccacga
      721 attctgatga gattgtcata aacaaacatg ttccccgcat atggcgattt ttctttcttg
      781 ttttttaaac cagcatcatg agcaaactga tcaatttctt cttccgttgg tttcgtattg
      841 atgttttgcg ctgtcgtttc tgcaatttta tttgccacac tctctgagtc gtgtttattt
      901 atagacgcac agaaatacaa tccggtaaac gcatcgcgca cattacgagc catattatca
      961 gtgtcttttt tcgttaccga ttccaattca agttcgttca gacgatgacg aagtgtgtgt
     1021 gctgcaatct cctggattga aggaggtaaa tctttaaatt ccatcgtcaa cctcatcagt
     1081 cggagtttct tgctaaccag cgatgcgcgc cagcttcggt tttaaacgtt ttacttttgg
     1141 tatacgtcat cgcggtaaac gtaccgtc
//
LOCUS       DAZUDJ010000289         1167 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.294, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000289 DAZUDJ010000000
VERSION     DAZUDJ010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1167
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.294"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..66
                     /locus_tag="ACHY1N_005430"
     CDS             <1..66
                     /locus_tag="ACHY1N_005430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HFS4047521.1"
                     /translation="MVDTSGAPDIEWPTPPAVQAR"
     gene            complement(38..640)
                     /locus_tag="ACHY1N_005431"
     CDS             complement(38..640)
                     /locus_tag="ACHY1N_005431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0098004 - virus tail fiber assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HFS4047522.1"
                     /translation="MDYAVLNNEFIATQAGNITVYNYDGETREYIFTSTEYLAVGVGI
                     PACSCLDAPGSYKTGYAICRSADFNSWEYVPDHRGEIVFSTETGESKEIKALGDYPEN
                     TTTIAPLSPYDKWDGEKWVTDTEAQHSAAVDAAEAQRQSLIDAAMASISLIQLKLQAG
                     RKLTQAETTQLNAVLDYIDAVTATDTSTAPDVIWPELPEA"
     gene            complement(640..>1167)
                     /locus_tag="ACHY1N_005432"
     CDS             complement(640..>1167)
                     /locus_tag="ACHY1N_005432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001115586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047523.1"
                     /translation="CIFINVGLGEGSALPVGVPVPWPSATPPTGWLKCNGAAFSAEEY
                     PELAKAYPTNKLPDLRGEFIRGWDDGRGVDSGRTLLTNQEHAVISHNHGIPTKVGSVT
                     NIPYGIEQVISDETIFSSAKTVGVDYWSNSERVFTYTTGGRNGAESVSSPDASSLIKE
                     TRPRNLAFAYIVRAA"
BASE COUNT          298 a          289 c          256 g          324 t
ORIGIN      
        1 atggtcgata cttccggtgc gccagatatt gaatggccta cgcctccggc agttcaggcc
       61 agatgacatc cggcgcggtg ctggtatctg ttgccgtcac cgcgtcaatg taatccagca
      121 cagcgttaag ctgggttgtt tctgcctgcg tcagtttccg tccggcctgt aatttcagct
      181 gaatcagact gatggaagcc attgcagcat caatcagtga ctggcgctgt gcttctgccg
      241 cgtctactgc ggcgctatgc tgtgcctcag tatcggttac ccatttctca ccatcccatt
      301 tatcgtatgg agataaaggg gcgatagtgg ttgtattttc agggtaatca cccagagctt
      361 tgatttcttt tgattctcct gtttctgtgc taaagacgat ttcaccacga tggtctggca
      421 catattccca tgagttaaaa tctgcagaac ggcagattgc atacccagtt ttgtatgagc
      481 caggagcatc taaacaggaa catgccggaa tgccgacacc cacagcaaga tattcagttg
      541 atgtgaaaat atattcccgt gtttcaccat catagttata aaccgtaata tttcctgcct
      601 gggtggcgat aaattcgtta tttaatacag cgtaatccat tatgcagccc tcacgatata
      661 cgcaaatgcc aggttccgtg gtctggtttc tttaattaaa gaggaggcat caggtgaact
      721 cactgattca gcaccatttc ttccaccagt ggtataagta aaaactcgct cactgttaga
      781 ccagtaatcc acaccaactg tttttgctga tgaaaaaatg gtttcatcag atataacctg
      841 ttctattcca tacgggatat tagtaactga ccccactttt gtaggtattc catgattatg
      901 agaaattact gcatgctctt gattcgttaa taaagtacga ccgctatcca ctccacgccc
      961 gtcatcccag ccacgaataa actcaccacg taaatcaggc aatttatttg tcggataagc
     1021 ctttgccagt tccgggtatt cttcagcaga aaaagcggca ccgttgcatt tcagccagcc
     1081 tgttggcgga gtggcggaag gccacggaac aggcacgcca acgggtaatg ccgaaccttc
     1141 tcccaaacca acgtttatga aaatgca
//
LOCUS       DAZUDJ010000290         1155 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.295, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000290 DAZUDJ010000000
VERSION     DAZUDJ010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1155
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.295"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            85..675
                     /locus_tag="ACHY1N_005433"
                     /pseudo
     CDS             85..675
                     /locus_tag="ACHY1N_005433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311739.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
     gene            complement(694..1136)
                     /locus_tag="ACHY1N_005434"
                     /pseudo
     CDS             complement(694..1136)
                     /locus_tag="ACHY1N_005434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001587377.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
BASE COUNT          371 a          181 c          217 g          386 t
ORIGIN      
        1 tataaatgaa tgcgttaaag catttacact caggatgaat atatgggaaa aattaaaatt
       61 gtggtttcag atcagcagcc gtttatgatt gatgggataa ttggatttct cggacattat
      121 cctgatttat ataaggttgt tgggggctat aaagatctga agaaagctat agcggagtgt
      181 aacaaatcta cagcctaaat atttatttta ggagaatttg caggtggaat gatggggtcc
      241 gaactcgtaa aatgggttaa atcgcataag atagatgctc atattattac atttgtagca
      301 aagatgccgt atattgattc aataaaattg cttgaagcag gtgcgaaagg atgcgtatgg
      361 aaaaccagtc acccggcgaa actaaatcgt gctattgatt cgattagtaa tggttacact
      421 tattttgata gtgtacatat ggattgtgaa aaaatatctt ccaggtattc ctctgataat
      481 caacttacaa atcgtgagtc agaaatatta caactcatag ctgatggtaa aacaaacaaa
      541 gaaatcgcta atttcttgca gttaagcaga aaaacagtcg aaactcatag actcaatatc
      601 atgaagaaat tagatgttca cagtggtatc gagttgatca aaacagcttt acgtatgggt
      661 gtttgcacta tataaaaaaa agaggcttta ggctcatttt gctgaagcct tacgattgtc
      721 tagttcatta agcctggtat atacaatata tattttgggg catattgctg tctctttttt
      781 tggttatcca ttgcaaaacc cgcattataa gtccccaggc attgccacgt tactccacaa
      841 cgtgaaaaat ggttatataa aatctcggtt cctattttaa tgttcagaca agggttatct
      901 aacaaatctc gttcatcttt tattattcca cgttttttta acaggggaat atgcatctgg
      961 tttatctgca ttaaccaata atctaaactc tttatattgt tattcttatc tctgttcttg
     1021 cctatgctat ccttttttag attgctttca acaagagcga tagctttaat taaatttggt
     1081 tcgattctga acattgttcc tgcttcatta gagcaagagt tgctggcgaa agacattttt
     1141 gtaataaata tacaa
//
LOCUS       DAZUDJ010000291         1139 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.296, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000291 DAZUDJ010000000
VERSION     DAZUDJ010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1139
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.296"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..1139
                     /locus_tag="ACHY1N_005435"
     rRNA            <1..1139
                     /locus_tag="ACHY1N_005435"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          282 a          262 c          356 g          239 t
ORIGIN      
        1 cgtgtatgaa gaaggccttc gggttgtaaa gtactttcag cggggaggaa gggagtaaag
       61 ttaatacctt tgctcattga cgttacccgc agaagaagca ccggctaact ccgtgccagc
      121 agccgcggta atacggaggg tgcaagcgtt aatcggaatt actgggcgta aagcgcacgc
      181 aggcggtttg ttaagtcaga tgtgaaatcc ccgggctcaa cctgggaact gcatctgata
      241 ctggcaagct tgagtctcgt agaggggggt agaattccag gtgtagcggt gaaatgcgta
      301 gagatctgga ggaataccgg tggcgaaggc ggccccctgg acgaagactg acgctcaggt
      361 gcgaaagcgt ggggagcaaa caggattaga taccctggta gtccacgccg taaacgatgt
      421 cgacttggag gttgtgccct tgaggcgtgg cttccggagc taacgcgtta agtcgaccgc
      481 ctggggagta cggccgcaag gttaaaactc aaatgaattg acgggggccc gcacaagcgg
      541 tggagcatgt ggtttaattc gatgcaacgc gaagaacctt acctggtctt gacatccaca
      601 gaactttcca gagatggatt ggtgccttcg ggaactgtga gacaggtgct gcatggctgt
      661 cgtcagctcg tgttgtgaaa tgttgggtta agtcccgcaa cgagcgcaac ccttatcctt
      721 tgttgccagc ggtccggccg ggaactcaaa ggagactgcc agtgataaac tggaggaagg
      781 tggggatgac gtcaagtcat catggccctt acgaccaggg ctacacacgt gctacaatgg
      841 cgcatacaaa gagaagcgac ctcgcgagag caagcggacc tcataaagtg cgtcgtagtc
      901 cggattggag tctgcaactc gactccatga agtcggaatc gctagtaatc gtggatcaga
      961 atgccacggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc atgggagtgg
     1021 gttgcaaaag aagtaggtag cttaaccttc gggagggcgc ttaccacttt gtgattcatg
     1081 actggggtga agtcgtaaca aggtaaccgt aggggaacct gcggttggat cacctcctt
//
LOCUS       DAZUDJ010000292         1129 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.297, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000292 DAZUDJ010000000
VERSION     DAZUDJ010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1129
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.297"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..1091)
                     /locus_tag="ACHY1N_005436"
     CDS             complement(<1..1091)
                     /locus_tag="ACHY1N_005436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase family protein"
                     /protein_id="HFS4047524.1"
                     /translation="MIQDAFVRQRARQLYWQGYPPAEISRLMGINPNTIYAWKKRDQW
                     DETPPVQRVTQSIDARLIQLTEKQNKTGGDFKEIDLLTRQLKKLHDGQPDVMAAGKKG
                     RAKKLKNHFTPKQIAALREKIISRLEWHQRGWFDSLTLCREAGIRNRMILKSRQIGAT
                     WYFAQEALLMALRDDVAQPYQRNQIFLSASRRQAFQFKSIIQKAAAEVDVELKGGDKI
                     ILSNGAELHFLGTSAASAQSYTGNFYFDEFFWVSRFAELRKVAGAMATLSGLRRTYFS
                     TPSTETHEAYAYWNGDRWNEKKATHKRQRFSVDWKTLHNGLICPDRTWRQIVTLEDVV
                     NHGWKHTDIDEIRDENTEDEFLNLYMCEFV"
BASE COUNT          244 a          313 c          282 g          290 t
ORIGIN      
        1 acaaactcac acatatagag attgaggaac tcgtcttcgg tgttttcatc acgaatttca
       61 tcaatatcgg tgtgtttcca gccgtgatta accacatctt ccagcgtgac aatttgccgc
      121 cacgtccggt cagggcagat aagcccgtta tgcagcgttt tccagtccac agaaaaacgc
      181 tggcgtttat gcgtggcctt tttctcgttc cagcggtcgc cgttccagta ggcgtatgcc
      241 tcgtgcgttt cggtggatgg cgtggagaag taggtgcgcc gcagtccgct gagggttgcc
      301 atagcgccag ccaccttgcg cagttcagca aagcgactga cccagaagaa ttcatcaaaa
      361 taaaaattgc ccgtatagga ctgtgccgac gcagcagaag tgccgagaaa atgcagctct
      421 gcgccgttgg agaggatgat tttatcgccc cctttcagct ccacatcaac ttcagccgcg
      481 gccttctgaa taatgctttt aaactggaac gcctgacgac gcgacgcaga caaaaaaatc
      541 tggttacgct ggtaaggttg cgccacatcg tcacgcagcg ccatcagcag agcttcctgt
      601 gcaaaatacc aggtcgcccc aatctgtcgg gatttcagga tcatcctgtt acgtatccct
      661 gcttccctgc aaagggtcag ggagtcaaac cagccccgct gatgccactc cagcctgctg
      721 atgatttttt cccgcagtgc ggcaatctgt ttcggcgtga aatgattttt gagttttttc
      781 gcccggcctt tctttcctgc ggccatcaca tccggctggc catcatgcag ctttttaagc
      841 tgccgggtca gcaggtctat ttccttaaag tcaccgcctg ttttattctg tttttcagta
      901 agctggatga ggcgcgcatc gatggactgc gtgacacgct gcacgggtgg cgtttcatcc
      961 cactggtcgc gttttttcca cgcataaatc gtgttcgggt ttattcccat cagacgtgat
     1021 atttctgcgg gcggataacc ctgccagtaa agttgccgcg cacgctggcg cacaaaagcg
     1081 tcctgaatca ttgctccccc tgagtaatta caggaagatt acccgcgcg
//
LOCUS       DAZUDJ010000293         1126 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.298, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000293 DAZUDJ010000000
VERSION     DAZUDJ010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1126
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.298"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..948
                     /locus_tag="ACHY1N_005437"
     CDS             <1..948
                     /locus_tag="ACHY1N_005437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708766.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047525.1"
                     /translation="HLTYTQARNITRFGTIESVTYDIAEGSVVSLAAGGISFALTASV
                     FWLSTGDRDAALQTAAVQAGKTFTRTLAVYVTTQQLHRLSVVQGMLKHIDFSTASPTV
                     RLALQKGTGAGNIRALNKVMKGTLVTSLALVAVTTGPDMIKMLRGRISGAQFIRNLAV
                     ASSGVAGGAVGSVAGGILFSPLGPFGALTGRVVGGVLGGMIASAVSGKIAGALVEEDR
                     VKILAMIQEQVTWLAGSFLLTGHEIENLNENLARVIDQNALEIIFAAGIQQRAATNML
                     IKPLVVSIIRQRPVMEYDASHLGNMVNRLEEALPPELPA"
     gene            1024..>1126
                     /locus_tag="ACHY1N_005438"
     CDS             1024..>1126
                     /locus_tag="ACHY1N_005438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047526.1"
                     /translation="MIHLFKTCMITAFILGLTWSAPLRAQDQRYISIR"
BASE COUNT          254 a          292 c          310 g          270 t
ORIGIN      
        1 catctgactt atactcaggc ccgtaatatc acccggttcg ggaccatcga atcggtcact
       61 tatgatattg ccgagggttc ggttgtcagt ctggcggccg gagggatcag ttttgccctg
      121 acggcatcgg tcttctggct cagcaccggc gatcgcgatg ctgccctgca gacagctgct
      181 gtccaggcag gaaaaacctt cacccgcaca ctggctgtct acgtcacaac ccagcaactc
      241 caccggctca gtgttgttca gggtatgctg aagcacattg atttttcgac tgccagcccg
      301 actgtccgac tggctcttca gaaggggacc ggtgcaggaa atatcagagc cctgaacaaa
      361 gtaatgaagg gtacgctggt gacatctctg gcactggtag ctgtcacaac cggccctgac
      421 atgatcaaaa tgttgcgggg acggatctcc ggtgcgcagt tcatcaggaa tcttgccgtg
      481 gcatcttccg gtgtggcagg tggagctgtc gggtcagtgg cgggcgggat actgttcagt
      541 ccactgggac catttggtgc actgacaggg cgtgtggttg gcggtgttct ggggggaatg
      601 attgcctccg ctgtatcagg aaaaattgcc ggagcgctgg ttgaagaaga tcgcgtcaaa
      661 attctggcaa tgattcagga gcaggtgaca tggcttgccg gcagtttcct gctgaccgga
      721 catgagattg aaaatctgaa cgagaatctg gcccgtgtta tcgatcagaa tgctctggag
      781 atcattttcg ccgccggtat acaacaacgg gccgcgacca atatgttaat caaaccactg
      841 gtggtcagta tcatcaggca acgccccgtc atggaatatg atgcatccca tctcggcaat
      901 atggttaacc gactggaaga agcattaccc ccggagttac cggcataacg gctattctgc
      961 gccttttacg ctttatcacc tgatttgtca gtgtcatcgt catgactcag agaggtaaat
     1021 accatgattc acctgttcaa aacctgcatg attaccgcct tcattctggg gttaacgtgg
     1081 tctgccccac tccgggcaca ggatcaacgt tacatcagta tacgca
//
LOCUS       DAZUDJ010000294         1119 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.299, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000294 DAZUDJ010000000
VERSION     DAZUDJ010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1119
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.299"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..151)
                     /locus_tag="ACHY1N_005439"
     CDS             complement(<1..151)
                     /locus_tag="ACHY1N_005439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFS4047527.1"
                     /translation="MLKQQDMTETARVVFNELSVTEPATVGEVAQNTYLSRERCQLIL
                     TQLVMA"
     gene            complement(393..923)
                     /locus_tag="ACHY1N_005440"
     CDS             complement(393..923)
                     /locus_tag="ACHY1N_005440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1133 family protein"
                     /protein_id="HFS4047528.1"
                     /translation="MIYPEITGKSGEHLRLNTLEAVWIQGKLRMWGRWSYIGGGKSGN
                     MFNRLLVSKKLTKTAVNEVLRSMKKSGLEKPELEAFFRDMTRGKQKSWLSHCTDTEAL
                     IIDRVISEVLGEYPGLINILRQRYEGRGMSKRKMAECLNRTHPEWCFSTCEKRIAGWL
                     AVAEHMLYVPMHDSFR"
     gene            complement(932..>1119)
                     /locus_tag="ACHY1N_005441"
     CDS             complement(932..>1119)
                     /locus_tag="ACHY1N_005441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFS4047529.1"
                     /translation="IAEPPDKRRRDLDNILKAPLDALTHAEVLIDDEQFDEINIVRGQ
                     PVSGGRLGVKIYKIESE"
BASE COUNT          276 a          314 c          210 g          319 t
ORIGIN      
        1 ccgccataac aagctgggtc agtattaact ggcagcgttc gcgtgaaagg taagtattct
       61 gcgcaacctc cccgactgtc gccggttcgg taacgcttaa ttcattaaac accactctgg
      121 cggtttcggt catatcctgc tgtttcagca tgtctttttc cctttttcgg ttaacgtgac
      181 acaccaataa ctcttgtcga aaaagccagc aagctgaaag aacggtatta ataaccacca
      241 gcgaatttat tgcgctgctg tatattacgg acacaaaaaa accaccttcc ggtggcttcc
      301 ttgtgcgaaa aaacttgcat ttcgcctcgc gatacagctt tgcgaagctt acaggaattc
      361 aagctgtttc tgcgtaaaaa agcaagcttt ttttatcgaa atgaatcgtg cataggtaca
      421 taaagcatgt gttcagccac ggctaaccaa cctgcaatac gtttctcaca tgtgctgaaa
      481 caccattccg ggtgagtacg atttaaacat tctgccattt ttctcttact cattccccgt
      541 ccttcgtacc tttgccggag aatattgatt agcccgggat attccccaag cacctcactg
      601 ataacgcgat caataatcaa cgcctctgtg tctgtacaat gtgacaacca gctcttctgc
      661 ttccctctgg tcatatcccg aaaaaatgcc tcaagttccg gtttttccag cccggatttc
      721 ttcatgctgc gtaaaacctc attaactgct gttttcgtca gctttttcga aaccagtaac
      781 cggttaaaca tatttccgga tttaccccca ccgatatacg accaccgccc ccacatccgt
      841 aatttcccct ggatccagac tgcttccagc gtgttcaggc gtaaatgttc gccgcttttg
      901 cctgtaattt ccggatatat catatttacg ctcactcact ctcaattttg taaatcttca
      961 cacccagccg tccaccagat actggctgac cgcgcacaat attgatttca tcaaactgct
     1021 cgtcatcaat gagcacttcc gcatgcgtca gcgcatccag cggtgctttc agaatgttgt
     1081 ccaggtcacg gcggcgctta tccggtggct ctgcaatca
//
LOCUS       DAZUDJ010000295         1114 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.300, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000295 DAZUDJ010000000
VERSION     DAZUDJ010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1114
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.300"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..174
                     /locus_tag="ACHY1N_005442"
     CDS             <1..174
                     /locus_tag="ACHY1N_005442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047530.1"
                     /translation="YCGDGELLHHIPEQLSKRERYTDKWQRRTHSLWRHRAWRASAFT
                     GICNDLAAASTFV"
     gene            138..713
                     /locus_tag="ACHY1N_005443"
     CDS             138..713
                     /locus_tag="ACHY1N_005443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HFS4047531.1"
                     /translation="MQRFGRRIDLRVKTGAEAIRALATQLPVFRQKLSDGWYQVRIAG
                     RDAGETELSSRLNEPLANGAVIHIVPRLAGAKSGGVFQAVLGAALIATAIWMPGISIA
                     FSDILFSMGAAMTLGGVAQMLAPKASTATTTSTDNGKQNTYFSSLDNMVAQGNVLPVL
                     YGEMRVGSRVISQEISTADEGDGGEIVVIGR"
     gene            774..>1114
                     /locus_tag="ACHY1N_005444"
     CDS             774..>1114
                     /locus_tag="ACHY1N_005444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HFS4047532.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPIEGPVDGLKS
                     VLLNSTPVLDSEENTNISGVTVVFRSGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRL"
BASE COUNT          255 a          270 c          358 g          231 t
ORIGIN      
        1 tactgtggtg acggcgagct gctgcaccat attcctgaac aactgagcaa acgagagagg
       61 tataccgaca aatggcagcg acgcacacac tccctctggc gtcaccgggc atggcgcgca
      121 tctgccttta cggggatttg caacgatttg gccgccgcat cgaccttcgt gtgaaaacgg
      181 gggctgaagc catccgcgca ctggccacac agctcccggt gtttcgtcag aaactgagcg
      241 acggctggta tcaggtacgg attgccgggc gtgatgcagg cgaaaccgaa ttatcatccc
      301 gtcttaatga gccgctggca aatggtgcag tgatccacat cgtgccgcgt cttgcgggag
      361 caaaaagtgg cggtgtgttt caggcggtgc tgggtgcggc gttgattgct acggcaatct
      421 ggatgccggg gatcagtatc gctttcagtg acattctctt ttcaatgggt gcggcgatga
      481 cgcttggcgg tgttgcacag atgctggcac cgaaagcgag taccgcaaca acgaccagca
      541 cggataacgg taagcagaac acgtatttct catcactgga taacatggtt gcccagggca
      601 atgttctgcc tgttctgtac ggtgaaatgc gtgtggggtc acgggtaatt tcgcaggaaa
      661 tcagcacggc agacgaaggg gatggtggtg aaatcgtggt gattggtcgc tgatgcagaa
      721 tgttttatgt gaaaccgcct ccgggcggtt ttgtcgttta tggagcgtga ggaatgggta
      781 aaggcagcag taaggggcat accccgcgcg aagcgaagga caacctgaag tccacgcagc
      841 tgctgagtgt gatcgatgcc atcagcgaag ggccgataga aggtccggtg gatggattaa
      901 aaagcgtgct gctgaacagt acgccggtgc tggacagtga ggagaatacc aatatctccg
      961 gcgtcacggt ggtgttccgg tcaggtgagc aggagcagac accgccggag gggtttgaat
     1021 cctccggctc cgagacggtg ctgggtacgg aagtgaaata tgacacgccg ataacccgga
     1081 ccatcacgtc ggcaaacatt gaccgtctgc gcct
//
LOCUS       DAZUDJ010000296         1106 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.301, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000296 DAZUDJ010000000
VERSION     DAZUDJ010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.301"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>1106)
                     /locus_tag="ACHY1N_005445"
     CDS             complement(<1..>1106)
                     /locus_tag="ACHY1N_005445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HFS4047533.1"
                     /translation="GGRVLAVNSQTRTLTLDREITLPSSGTTLISLVDGSGNPISVEV
                     QSVTDGVKVKVSRVPDGVAEYSVWGLKLPTLRQRLFRCVSIRENDDGTYAITAVQHVP
                     EKEAIVDNGAHFDGDQSGTVNGVTPPAVQHLTAEVTADSGEYQVLARWDTPKVVKGVS
                     FMLRLTVAADDGSERLVSTARTAETTYRFTQLAPGNYRLTVRAVNAWGQQGDPASVSF
                     RIAAPAAPSQIELTPGYFQITATPHLAVYDPTVQFEFWFSETRITDIRQVETTARYLG
                     TALYWIAASINIKPDHDYYFYIRSVNTVGKSAFVEAVGQPSDDASGYLDFFKGQITES
                     HLGKELLEKVDLTEDNASRLEEFSKEWKDANDKW"
BASE COUNT          211 a          353 c          292 g          250 t
ORIGIN      
        1 tccacttatc gttggcgtcc ttccactctt tcgaaaactc ctccagtctg ctggcgttat
       61 cctccgtcag gtcgactttt tccagcagct ccttgccgag atgggattcg gttatctggc
      121 ctttgaaaaa atccagatag ccggatgcat catcactcgg ctggccaaca gcctccacaa
      181 atgccgattt gccaacggtg ttcacactgc ggatgtaaaa ataataatca tggtccggtt
      241 tgatattgat actggcggct atccagtaca gcgccgtgcc aagatagcgg gctgtggttt
      301 caacctgcct gatatcggta atccgcgttt ccgagaacca gaactcaaac tgtaccgtcg
      361 ggtcataaac cgcaagatgc ggcgtggcgg ttatctgaaa atagcccggc gtcagctcaa
      421 tctgtgacgg cgctgccggt gcggcaatcc tgaacgatac cgatgccgga tcgccctgct
      481 gcccccacgc atttactgcc cggactgtca gcctgtagtt ccccggcgcc agttgtgtga
      541 agcggtatgt ggtttccgcc gtccgggctg tgctgaccag ccgctcactg ccgtcatccg
      601 cggccacggt caggcgaagc atgaaactca cgcccttcac caccttcggc gtatcccagc
      661 gggccagtac ctgatactcc ccgctgtctg cggtgacttc ggcagtcagg tgctgcactg
      721 ctggcggcgt gacaccattc accgtgccgc tctggtcgcc gtcaaagtgc gccccgttat
      781 ccacgatggc ttctttttcc ggtacatgct gcacggcggt gatagcatac gtgccgtcat
      841 cgttctcacg gatactcaca cagcggaaca ggcgctggcg caacgtcggc aacttcagcc
      901 cccacacgct gtattcagca acaccgtcag gaacacggct cactttcacc ttcacgccgt
      961 cggtgacgga ctgaacctcc acgctgatcg gattgccact tccgtcaacc aggcttatca
     1021 gcgtggtacc ggaggatggc agcgtgattt cacggtcgag cgtcagcgtc cgggtctggc
     1081 tgtttaccgc cagcacgcgc ccgccg
//
LOCUS       DAZUDJ010000297         1081 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.302, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000297 DAZUDJ010000000
VERSION     DAZUDJ010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1081
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.302"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1081
                     /locus_tag="ACHY1N_005446"
     CDS             <1..>1081
                     /locus_tag="ACHY1N_005446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS domain-containing protein"
                     /protein_id="HFS4047534.1"
                     /translation="YDRDYGWNDNGDLVRISGPRQTREYGYSATGRLESVRTLAPDLD
                     IRIPYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYHYDEYGRLTEKTDRIPT
                     GVIRTDDERTHHYHYDSQHRLVFHTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERDL
                     TGWMSLSRKPEETWYGWDGDRLTTVQTDTTRIQTVYQPGSFTPLIRVETENGEREKAQ
                     RRSLAEKLQQEGSEDGHGVVFPAELVGLLDRLEGEIRANCVSSESRQWLAQCGLTVER
                     LAAQIEPVYLPERKIHLYHCDHRGLPLALISEDGNTAWSAEYDEWGNQLNEENPHHLH
                     QPYRLPGQQYDKESGLYYNRHRYYDP"
BASE COUNT          246 a          307 c          373 g          155 t
ORIGIN      
        1 tatgaccgtg actacgggtg gaatgacaac ggcgacctgg tgcgcatcag cggtccgcga
       61 cagacgcggg aatacggcta cagcgccacg ggcaggctgg agagcgtgcg caccctcgca
      121 ccggacctgg acatccgcat cccgtatgcc accgacccgg cgggaaaccg cctgccggac
      181 ccggagctac acccggacag cacgctcacg gcgtggccgg ataaccgcat cgcagaggat
      241 gcgcactatg tttaccacta tgatgaatac ggcagactga cggagaagac ggaccgtatc
      301 ccgacgggtg tgatacggac ggacgacgag cggacccacc actaccacta cgacagccag
      361 caccgcctgg tgttccacac gcggatacag catggcgagc cactggtcga gagccgctac
      421 ctctacgacc cgctgggacg gcgaatggcg aaacgggtat ggcggcggga gcgtgacctg
      481 acggggtgga tgtcgctgtc gcgtaaaccg gaggagacat ggtacggctg ggacggcgac
      541 aggctgacga cggtacagac cgacaccacg cgtatccaga cggtatacca gccggggagc
      601 ttcacgccgc tcatccgggt cgagacagag aacggcgagc gggagaaagc gcagcgccgc
      661 agcctggcgg agaagttaca gcaggaaggg agcgaagacg gtcacggtgt ggtgttcccg
      721 gctgaactgg tggggctgct ggacaggctg gagggggaaa tccgggcaaa ctgcgtgagc
      781 agtgaaagcc gccagtggct tgcgcagtgc gggctgacgg tggagcggct ggcggcacag
      841 atagagccgg tttatttgcc tgagcgaaaa atacatcttt atcactgtga ccaccggggc
      901 ctgccgctgg cgcttatcag tgaagacggc aatacggcgt ggagcgcgga atatgatgaa
      961 tggggcaacc agcttaatga ggagaacccg catcacctgc accagccgta ccggctgccg
     1021 gggcagcagt atgataagga gtcggggctg tactataacc gtcaccggta ctacgatccg
     1081 t
//
LOCUS       DAZUDJ010000298         1078 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.303, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000298 DAZUDJ010000000
VERSION     DAZUDJ010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1078
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.303"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..188)
                     /locus_tag="ACHY1N_005447"
     CDS             complement(<1..188)
                     /locus_tag="ACHY1N_005447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HFS4047535.1"
                     /translation="MKIKHEHIRMAMNAWARPDGEKVPAAGITQAYFELGMTFPELYD
                     DSHPEALARNTQKIFRWV"
     gene            complement(172..453)
                     /locus_tag="ACHY1N_005448"
     CDS             complement(172..453)
                     /locus_tag="ACHY1N_005448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdaS family helix-turn-helix protein"
                     /protein_id="HFS4047536.1"
                     /translation="MEELRIFLNSLSSDEQRMFACECGTSIGYLRKALSKGQVLGASL
                     CVLIERASNGEVTRQQLRPFDWMNIWPELEDTKTLTQPLSRSLIHENQA"
     gene            554..973
                     /locus_tag="ACHY1N_005449"
     CDS             554..973
                     /locus_tag="ACHY1N_005449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047537.1"
                     /translation="MDKYEFRRQQLIKIRDEKCDGKAVNVARKIGREPSYVSRMLYPE
                     GKKGKKRIADDMVEIIEESFGLPRGWMDGIVSSSTNTASSYETRVLTPRQRIFLDLLD
                     ELPESEADKLLKTLEEKKQYYNMIYEEIRKKKAQNAS"
BASE COUNT          339 a          243 c          215 g          281 t
ORIGIN      
        1 tctacccagc ggaaaatttt ctgggtattg cgagccaggg cttccggatg gctgtcgtca
       61 tacagttctg ggaacgtcat acccaactca aaataagcct gggttattcc agctgctgga
      121 actttttcgc catcaggacg cgcccaggca ttcatcgcca tgcggatgtg ttcatgcttg
      181 attttcatga atcaagctcc tagaaagtgg ttgtgttaac gttttggtat cttccagctc
      241 gggccaaata ttcatccaat caaaaggcct tagttgctga cgtgtaactt caccattact
      301 ggctcgctca ataaggacac ataacgatgc ccctaacact tgacctttac tcaatgcctt
      361 tcttagataa ccgatgctgg taccacactc gcatgcaaac atacgctgtt catctgacga
      421 aagagaattg agaaatattc ttaattcttc catagctact ccttagtaaa cacagcaaag
      481 aatacccaca ggtaaacaaa agtcaatacc cacaggttgt ttaccttgcg gtaatcgcat
      541 ctattattta cctatggaca aatatgaatt tagacgacag caactcatca aaattcgtga
      601 tgagaaatgc gatggtaaag cggttaacgt ggccagaaag atcgggcgcg agccttctta
      661 tgtatcaaga atgttgtacc cagaggggaa aaagggaaaa aaacggatcg ctgatgatat
      721 ggtggagatt atcgaagagt cctttgggtt accccgggga tggatggatg gtatcgtttc
      781 atcatcaacg aacacagcct ccagttatga aacaagggtt ctaacgccac gacaacgtat
      841 ttttttagat ctcttagacg aactgccaga aagtgaagcg gataaattat taaaaactct
      901 tgaagagaaa aaacagtatt acaatatgat ctacgaagaa atccgtaaaa agaaagcaca
      961 aaacgcatca tagctcacca aacaactagt caccagttaa gacaccgcaa aaatttaccc
     1021 atgggtattt actttttaaa tacctatggg tatccttctt ttcataccaa cccacccc
//
LOCUS       DAZUDJ010000299         1076 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.304, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000299 DAZUDJ010000000
VERSION     DAZUDJ010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1076
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.304"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1076
                     /locus_tag="ACHY1N_005450"
     CDS             <1..>1076
                     /locus_tag="ACHY1N_005450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1983 domain-containing protein"
                     /protein_id="HFS4047538.1"
                     /translation="TYGVWGLSLPSLRRRLFRCVSIRENTDGTFAITAVQHVPEKEAI
                     VDNGASFEPQSGTLNSVIPPAVQHLTVEVSAADGQYLAQAKWDTPRVVKGVRFSLRLT
                     SGSGEGSRLVTTAITADTEHRSSGLPLGEYTLTVRAINSYGQQGEPATTTFRINAPAK
                     PATIELTPGYFQITAVPRLAVYDPTVQFEFWFSETKIADTSQVETSARYLGTGSQWSV
                     SGPHIKPGKDFWFYVRSVNLVGKSAFVEVSGQPSNDGEGYLEFFREKIGKLHLAQGVW
                     ELIDNSQLADEMAEMKTSITETRNEITQTVSKTLENQSATIQQIQRVQKDTNDDLAAL
                     YMLKVQKTKDGIPYVAGIGAGIED"
BASE COUNT          267 a          281 c          331 g          197 t
ORIGIN      
        1 gacatacggt gtatggggac tctccctgcc gtcactgcgt cgtcgcctgt tccgctgtgt
       61 ctccatccgg gaaaacacgg acggcacctt tgccatcacg gcggtgcagc acgtaccgga
      121 aaaggaagcc atcgtggata acggggccag ctttgagccg cagtcaggca ccctgaacag
      181 cgtcatccct ccggcagtgc agcacctgac ggtggaggtg agcgcagctg acggccagta
      241 tctggcacag gcgaaatggg acacgccgcg ggtggtgaag ggggtgcgct tcagtctgcg
      301 actgaccagc ggaagcggag aaggcagccg tctggtgacc accgccatca ccgcggatac
      361 agagcatcgt tccagtggtc tgccgctcgg ggaatacacc ctgacagtca gggcaattaa
      421 cagttatggc cagcagggcg aaccggccac caccaccttc cggattaacg cgccagcaaa
      481 acccgccacc attgaactga cgccggggta ttttcagata acagcggtcc cgcgtcttgc
      541 ggtgtatgac ccgacggtac agtttgagtt ctggttttcg gagacaaaaa ttgcagacac
      601 atctcaggtg gaaacctctg cccgttatct ggggaccggc agtcagtgga gtgtatccgg
      661 cccgcacatt aagcccggga aggatttctg gttttacgtg cgcagcgtca acctggtggg
      721 gaaatctgcg tttgtggaag tcagcgggca gcccagcaat gatggtgaag ggtatctgga
      781 atttttccgg gaaaaaatag gaaaactgca tctggctcag ggggtgtggg aactgataga
      841 taacagccag cttgcagatg agatggcgga gatgaagacc agcatcacgg aaacccgcaa
      901 tgaaatcaca cagacggtca gtaaaacact ggagaaccag agcgccacca tacagcagat
      961 acagcgcgtg cagaaggaca caaatgatga cctggctgcg ctgtacatgc tgaaggttca
     1021 aaaaacgaaa gacggcattc cctatgtggc cgggattggt gcagggattg aggata
//
LOCUS       DAZUDJ010000300         1069 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.305, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000300 DAZUDJ010000000
VERSION     DAZUDJ010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.305"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(54..140)
                     /locus_tag="ACHY1N_005451"
     CDS             complement(54..140)
                     /locus_tag="ACHY1N_005451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047539.1"
                     /translation="MSAELIRAMAFAIRIVAIAVLVWAIRWW"
     gene            complement(152..307)
                     /locus_tag="ACHY1N_005452"
     CDS             complement(152..307)
                     /locus_tag="ACHY1N_005452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000788417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047540.1"
                     /translation="MGDVVFVGAAGVTVTDDISRALAFAIKWVAVGIAVSPMLYGLAK
                     LVIALKS"
     gene            complement(271..402)
                     /locus_tag="ACHY1N_005453"
     CDS             complement(271..402)
                     /locus_tag="ACHY1N_005453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047541.1"
                     /translation="MSDKLITPAKVLCVIVGISFSLMLVALFLSLAWVMLSSSGLLG"
     gene            complement(695..>1069)
                     /locus_tag="ACHY1N_005454"
     CDS             complement(695..>1069)
                     /locus_tag="ACHY1N_005454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003796 - lysozyme activity [Evidence
                     IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA];
                     GO_process: GO:0016998 - cell wall macromolecule catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="HFS4047542.1"
                     /translation="GAIMVDGKPVIPGMKLSKEKCDQVNAIERDKALAWVEKNIKVPL
                     TEPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRRGACEAIRWWIMDGGRDCRIRSN
                     NCYGQVSRRDQESALACWGIDR"
BASE COUNT          303 a          318 c          205 g          243 t
ORIGIN      
        1 caccacaggc taccagcagg acaataatca ccacacacag aacacggttc atatcaccac
       61 caacggattg cccagaccag aacagcaatg gccacaatac gaatggcaaa tgccattgcc
      121 cgaataagtt cagcactcat ctttttaaag ttcacgattt cagcgcaatg accagttttg
      181 ccagcccata cagcatcgga gacacagcaa taccaacagc cacccactta atagcaaaag
      241 ccagcgctct gctgatgtca tcagtcactg tcaccccagc agccccgacg aagacaacat
      301 cacccaggcg agggacagaa aaagagcaac cagcattagt gaaaatgaaa taccgacaat
      361 cacacacagg acctttgccg gcgttatgag tttgtctgac atagctaccc cttaattgcc
      421 acaattaact gggatactac ccataaaaaa gggatgctcc agaccagcaa aaatttccag
      481 tttggtaatt gactaatcat gagtcgcaac tccctaatca gtttgctaaa atcaatcaag
      541 gcagcctccc atagcttact gccataaaaa caaaaccccg cttgctgcca acaaacgggg
      601 tttttacttt tactcactta cattttgcca gttcgcagga tttcatgtta tccgcccgcg
      661 tggccatgcc ttatttttca gcaaaatatt ctgcttatct gtcgataccc cagcacgcca
      721 gcgcgctctc ctggtcacga cgggatacct gaccgtagca gttgtttgaa cgaatacggc
      781 agtctctgcc accgtccata atccaccagc gaatcgcctc acatgctccc ctgcgatcac
      841 cagcattaat tcgtctgtaa aacgtcgacg ggaaacactt accgggacca atgttgtacg
      901 gacagaatga cgcgatcccc gctttctggg gttcggtcaa tggcactttg atgtttttct
      961 ccacccatgc cagcgcctta tcacgttcga tggcgttaac ctggtcgcat ttttccttcg
     1021 acagcttcat gccaggaatc acaggcttac catccaccat gatggcgcc
//
LOCUS       DAZUDJ010000301         1045 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.306, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000301 DAZUDJ010000000
VERSION     DAZUDJ010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.306"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1045
                     /locus_tag="ACHY1N_005455"
     rRNA            <1..>1045
                     /locus_tag="ACHY1N_005455"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          283 a          224 c          333 g          205 t
ORIGIN      
        1 cgggacacgt ggtatcctgt ctgaatatgg ggggaccatc ctccaaggct aaatactcct
       61 gactgaccga tagtgaacca gtaccgtgag ggaaaggcga aaagaacccc ggcgagggga
      121 gtgaaaaaga acctgaaacc gtgtacgtac aagcagtggg agcacgctta ggcgtgtgac
      181 tgcgtacctt ttgtataatg ggtcagcgac ttatattctg tagcaaggtt aaccgaatag
      241 gggagccgaa gggaaaccga gtcttaactg ggcgttaagt tgcagggtat agacccgaaa
      301 cccggtgatc tagccatggg caggttgaag gttgggtaac actaactgga ggaccgaacc
      361 gactaatgtt gaaaaattag cggatgactt gtggctgggg gtgaaaggcc aatcaaaccg
      421 ggagatagct ggttctcccc gaaagctatt taggtagcgc ctcgtgaatt catctccggg
      481 ggtagagcac tgtttcggca agggggtcat cccgacttac caacccgatg caaactgcga
      541 ataccggaga atgttatcac gggagacaca cggcgggtgc taacgtccgt cgtgaagagg
      601 gaaacaaccc agaccgccag ctaaggtccc aaagtcatgg ttaagtggga aacgatgtgg
      661 gaaggcccag acagccagga tgttggctta gaagcagcca tcatttaaag aaagcgtaat
      721 agctcactgg tcgagtcggc ctgcgcggaa gatgtaacgg ggctaaacca tgcaccgaag
      781 ctgcggcagc gacgctgatg cgttgttggg taggggagcg ttctgtaagc ctgtgaaggt
      841 gtgctgtgag gcatgctgga ggtatcagaa gtgcgaatgc tgacataagt aacgataaag
      901 cgggtgaaaa gcccgctcgc cggaagacca agggttcctg tccaacgtta atcggggcag
      961 ggtgagtcga cccctaaggc gaggccgaaa ggcgtagtcg atgggaaaca ggttaatatt
     1021 cctgtacttg gtgttactgc gaagg
//
LOCUS       DAZUDJ010000302         1026 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.307, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000302 DAZUDJ010000000
VERSION     DAZUDJ010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1026
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.307"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..303
                     /locus_tag="ACHY1N_005456"
     CDS             <1..303
                     /locus_tag="ACHY1N_005456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF932 domain-containing protein"
                     /protein_id="HFS4047543.1"
                     /translation="ILPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDL
                     WSAYQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETLLESMR"
     gene            303..548
                     /locus_tag="ACHY1N_005457"
     CDS             303..548
                     /locus_tag="ACHY1N_005457"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047544.1"
                     /translation="MKHIPEGVIQVPESPDAPEALPGCRSISDDDLCAWCTRLLYRPG
                     EISLCRLSTGNDIWPSVCDRNGYAYGCPEFQPNIIHP"
     gene            642..>1026
                     /locus_tag="ACHY1N_005458"
     CDS             642..>1026
                     /locus_tag="ACHY1N_005458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HFS4047545.1"
                     /translation="MKTLSQNTTSSACAPETGLQQLVATIVPDEQRISFWPQHFGLIP
                     QWVTLEPRVFGWMDRLCEDYCGGIWNLYSLSNGGAFMAPEPDDDDDETWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHACRTE"
BASE COUNT          232 a          292 c          275 g          227 t
ORIGIN      
        1 attctgccgc caccggcacg ccaggcgctg gcacaggcgg cactgactta ccgttatggt
       61 gacgaacatc agcccgtcac caccgccgac attctgacgc cacgacgccg ggaggattac
      121 ggtaaggacc tgtggagtgc ttatcagacc atccaggaga atatgctgaa aggcgggatt
      181 tccggtcgca gtgcaaaagg aaaacgtatc cacacccgtg ccattcacag catcgacacc
      241 gatattaagc tcaaccgcgc attgtgggtg atggcagaaa cgctgctgga gagtatgcgc
      301 tgatgaaaca tatccctgaa ggcgtgattc aggtaccaga atcccccgac gccccggaag
      361 cgctgccggg gtgtcgttcc atttctgatg atgacctgtg cgcctggtgt acccgtctgc
      421 tttaccgtcc cggagaaatc agtctgtgca gactgagtac aggcaatgac atctggccat
      481 ccgtctgtga ccggaacggt tacgcgtacg gctgtccgga atttcagccg aatatcattc
      541 atccctgata ttaccgggtc tcacggtcag tgatgaacgt gatgttgcca gctcccgacc
      601 tttactccct ctcatttatt cacattacaa ggatttcata catgaaaaca ttgtctcaga
      661 acaccacctc ttcggcctgt gcaccggaga ctggcctgca acaactggtt gccaccatag
      721 tccctgatga acagcgcatc agcttctggc cgcagcactt tggtctcatt ccacagtggg
      781 tgaccctgga gccccgtgtc ttcggctgga tggaccgtct gtgcgaagac tactgcggtg
      841 gtatctggaa tctgtacagt ctgagcaacg gcggggcatt tatggccccc gaaccggatg
      901 acgatgatga cgaaacatgg gtactgttca atgccatgaa cggtaaccgc gctgaaatga
      961 gcccggaagc cgctggcatt gctgcctgtc tgatgacgta cagtcatcac gcctgtcgta
     1021 cggagt
//
LOCUS       DAZUDJ010000303         1021 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.308, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000303 DAZUDJ010000000
VERSION     DAZUDJ010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1021
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.308"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>1021
                     /locus_tag="ACHY1N_005459"
     CDS             <1..>1021
                     /locus_tag="ACHY1N_005459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047546.1"
                     /translation="EAKDNLKSTQMMSVIDAIGEGPVEGPVKGLQSILVNKTPLTDTD
                     GNPVIRGVTAVWRAGEQEQTPPEGFESSGAETALGVEVTKAKPVMRTITSANIDRLRV
                     TFGVQSLLETTSKGDRNPSSVRLLIQLQRNGNWVTEKDVTINGKTTSQFLASVILDNL
                     PPRPFNIRMVRETADSTTDQLQNKTLWSSYTEIIDVKQCYPNTAIVGLQVDAEQFGGQ
                     QMTVNYHIRGRIIQVPSNYDPEKRTYSGIWDGSLKPAYSNNPAWCLWDMLTHPRYGMG
                     KRLGAADVDKWALYAIAQYCDQMVPDGFGGTEPRMTFNAYLSQQRKAWDVLSDFCSAM
                     RCMPVW"
BASE COUNT          239 a          268 c          322 g          192 t
ORIGIN      
        1 gaggcaaagg acaatcttaa gtccacgcag atgatgagcg tgattgatgc catcggtgag
       61 ggaccggtgg aaggtccggt gaaggggctg cagagtattc tggtgaacaa aaccccgctg
      121 acggacacgg acggtaatcc tgtgatacgt ggtgtgacag cggtctggcg cgccggggag
      181 caggagcaga caccacctga aggctttgag tcctccggag ctgaaaccgc actgggcgtg
      241 gaagtgacga aagcaaagcc ggtgatgcgc accattacgt ccgcgaacat tgaccgcctg
      301 cgggtcacct tcggggtgca gtcactgttg gagaccacct caaagggcga ccgtaatccc
      361 tcttctgtcc gcctgctgat tcagttacag cgtaacggta actgggtgac agaaaaggac
      421 gtcaccatta acggcaagac cacctcacag ttcctggcct cggtgattct ggataatctg
      481 cctccccggc cctttaacat ccggatggtc agggagacgg cggacagcac cacggaccag
      541 ctgcagaata agacgctgtg gtcgtcatac accgaaatca tcgatgtgaa acagtgctac
      601 ccgaacacgg ccattgtggg gctgcaggtg gatgcggagc agttcggcgg ccagcagatg
      661 acggtgaact accatatccg tggtcgcatc attcaggtac cgtcaaacta tgacccggaa
      721 aaacgcacgt acagcggtat ctgggacggc agtctgaaac cggcatacag caataacccg
      781 gcctggtgtc tgtgggacat gctgacccac ccgcgctacg gaatgggaaa acgcctgggg
      841 gcggcggatg tggacaagtg ggcgctgtat gccattgcgc agtactgcga ccagatggtc
      901 ccggatggtt tcgggggcac agagccgcgg atgaccttta atgcgtacct gtcacaacag
      961 cgtaaggcat gggatgtgct cagtgatttc tgctcggcga tgcgctgtat gccggtatgg
     1021 a
//
LOCUS       DAZUDJ010000304          991 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.309, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000304 DAZUDJ010000000
VERSION     DAZUDJ010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.309"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            3..257
                     /locus_tag="ACHY1N_005460"
                     /pseudo
     CDS             3..257
                     /locus_tag="ACHY1N_005460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
     gene            296..>991
                     /locus_tag="ACHY1N_005461"
     CDS             296..>991
                     /locus_tag="ACHY1N_005461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HFS4047547.1"
                     /translation="MITDLILHNNPRMKTITLNDNHIAHLNAKNTTELEYLNLSNNNL
                     LPTNDIDQLISSKHLWHVLVNGINNDPLAQMQYWTAVRNIIDDTNEVTIDLSGLNLTT
                     QPPGLQNFTSINLDNNQLTHFDATNYDRLVKLSLNSNTLESINFPQGRNVSITHISMN
                     NNALRNIDIDRLSSVTYFSAAHNQLEFVQLESCEWLQYLNLSHNQLTDIVAGNKNELL
                     LLDLSHNKLTSLHN"
BASE COUNT          350 a          196 c          164 g          281 t
ORIGIN      
        1 cggtggttgt aactggtttg ttagctgcga acgtagcaca cgctgccgaa gtctataaca
       61 aggatggtaa taaactcgac ctttatggca aggttaccgc tctacgttat tttactgatg
      121 ataagcgtga cgatggtgat aaaacttatg cccgtctcgg ctttaaagga gaaacgcaaa
      181 tcaatgatca aatgattggt tttggtcact gggaatatga ttttaaaggc tataacgatg
      241 aagccaacgg ttcgcgcggc aacaatctct gattgagtta agtgcccatc acaatatgat
      301 cactgacctt atattacaca ataatcccag gatgaaaaca atcactttaa acgacaacca
      361 tattgcacat ttaaacgcca aaaacactac agaactggaa tatttaaact taagcaataa
      421 caatttactg ccaaccaatg acattgatca actaatatca tcaaaacatc tttggcatgt
      481 attagttaac ggcatcaaca atgatccact tgcacaaatg cagtactgga ctgcagtaag
      541 aaatataatt gatgacacta atgaagtgac cattgattta tcaggactta atttaaccac
      601 tcaaccacca gggctgcaaa acttcacctc tatcaatctt gataataacc aactcacaca
      661 ttttgatgca accaactacg atagactcgt aaagctaagt ctgaatagta atactcttga
      721 gtcaataaat tttcctcaag gcagaaatgt aagtattaca catatatcta tgaataataa
      781 tgctctcaga aatattgata tagataggct ttcatcagtt acttatttta gtgcggcaca
      841 taatcaacta gagtttgtgc aattagaatc ttgcgaatgg ctgcaatacc tgaatctcag
      901 ccataatcaa ttaactgata ttgttgcagg taataaaaat gaactcttac tgctggatct
      961 atcccataat aaactaacaa gtttacacaa t
//
LOCUS       DAZUDJ010000305          976 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.310, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000305 DAZUDJ010000000
VERSION     DAZUDJ010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..976
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.310"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            126..626
                     /locus_tag="ACHY1N_005462"
                     /pseudo
     CDS             126..626
                     /locus_tag="ACHY1N_005462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311747.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            628..921
                     /locus_tag="ACHY1N_005463"
     CDS             628..921
                     /locus_tag="ACHY1N_005463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="invasion protein"
                     /protein_id="HFS4047548.1"
                     /translation="MSLVGYNSNIIITIALISLLSACTRENSLKENQNKRSGESQAIV
                     DARQFFSEHPEYISSAELEQKLYREFAQVTTVPAYKEMSMYQLLIISQDRLTH"
BASE COUNT          345 a          174 c          150 g          307 t
ORIGIN      
        1 aactttattt acaatttaag gtataaaccc tattccctca atgttaagca aatataacaa
       61 tcactcttat tttaaatttt acacgtaata tttaccctaa atgattttag agtacaggtg
      121 ggcatatgca agtcttttcc agtgatgtct acttcactgt aggcactaat gcattattag
      181 catcccaaaa agaatattac agcgatttag ttgcgttggt tgatcttgga cattcgttcg
      241 ttgttattga tgagcatcaa catcgaaatc tcaaaccaaa tacaaaacct gtaaacatcc
      301 ttttgagcaa caatttcatc aggatcaata agaatattac attatctgat ttaacgcatt
      361 tcctggtttc aaatcttcat acacaaaatg tgtattccac acaagaacca cttatccatg
      421 atgagataga tatcctgcgg ttatgtgttt cttactcgtt aaaacaaata gccattatta
      481 aaggaattga ttataaaaca atatcatatc acaaaataag agctctaaat aaacttaaca
      541 taaaaggtac tgtttagttg tttatagcac tctgtgaatg ggataaacat tattttaaac
      601 tccaatcttg cgtaagtgaa agttgatatg tcattagtag gatataatag taacatcata
      661 ataaccatcg cgctgatatc gttgctctct gcatgcacca gagaaaattc attaaaggag
      721 aatcaaaata aaagaagtgg cgaatcccaa gcgatagtag atgcaagaca gttctttagc
      781 gaacacccgg aatatatatc atcagcagaa ctggagcaaa agctatatcg cgaatttgca
      841 caggttacta cagttccagc ttataaagag atgagtatgt atcaattgct tatcatttca
      901 caagatcgtt taactcatta aataaggatc tacacgcttt ttgcgtgtag atccttataa
      961 atttctgact acgaca
//
LOCUS       DAZUDJ010000306          974 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.311, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000306 DAZUDJ010000000
VERSION     DAZUDJ010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.311"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            274..>974
                     /locus_tag="ACHY1N_005464"
     CDS             274..>974
                     /locus_tag="ACHY1N_005464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HFS4047549.1"
                     /translation="MAFKHYDVVRAASPSDLAEKLTHKLKEGWQPYGGPVAITPYTLM
                     QAVAIEGDPQVGPSSEPDWFYVVVLAGQSNGMAYGEGLPLPDSYDAPDPRIKQLARRS
                     TVTPGGESCTYNDIIPADHCLHDVQDMSTLNHPKADLSKGQYGCVGQGLHIAKKLLPY
                     IPNNAGILLVPCCRGGSAFTQGAEGTFSADTGASQDSARWGVGKPLYQDLIARTKAAL
                     QKNPKNVLLAVCWMQG"
BASE COUNT          224 a          255 c          282 g          213 t
ORIGIN      
        1 ggcacatagc gccactctcc agcccctctc cggaggggct ttcttatgga caaaaaaagc
       61 ccgcgcaggg agacgcgggc ggcaaggaat aaacaacaaa acgtgaagta atatttcagc
      121 tggcgaataa tatccgacag taatcactct gcgcaatagc gcggcctttt tcgtattgcg
      181 ggctgttgtc tctcttctgc cattgtcctg taacttccgg acttcagccc gctcctcatt
      241 ttactcacaa tattatcccg gccgggagga ttcatggcat ttaaacacta tgatgttgtc
      301 agggcggcgt cgccgtcaga ccttgcggaa aagctgacac acaaactgaa agagggctgg
      361 cagccatacg gcggaccggt tgccattacg ccgtacacac tgatgcaggc ggtggctatt
      421 gaaggagatc cacaggtcgg cccttcatct gagccggact ggttctacgt ggttgtgctt
      481 gccggacagt ccaacggcat ggcctacggt gaagggcttc cgttaccgga ttcttacgat
      541 gctccggatc cgcgcattaa acagctggcg cgccgcagca cggtaactcc gggtggagag
      601 agttgtacgt ataacgacat cattccggct gaccactgcc tgcatgatgt gcaggatatg
      661 agtacgctga atcatccgaa ggcagacctg agcaaagggc agtacggctg tgtcggccag
      721 ggcttacata ttgccaaaaa actgcttccg tatatcccga ataacgcggg gatcctgctg
      781 gtaccatgct gtcgtggtgg ttctgcattc acccagggcg ctgaggggac attcagtgcg
      841 gacacggggg ccagccagga ttcggcacgc tggggtgtgg gtaaaccgtt atatcaggac
      901 ctgattgcgc gcactaaagc tgcattacag aagaacccga aaaatgtgtt gctggcggtg
      961 tgctggatgc aggg
//
LOCUS       DAZUDJ010000307          972 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.312, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000307 DAZUDJ010000000
VERSION     DAZUDJ010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.312"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>972)
                     /locus_tag="ACHY1N_005465"
     CDS             complement(<1..>972)
                     /locus_tag="ACHY1N_005465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047550.1"
                     /translation="VWMQISSTLKGALDINSLIIDYDNEDVQSYWEDVVLPNLNDNGN
                     KALTRDETIAYIKDSKPCRRIKRLIHDDAVLEDQKDKNFIAKMIAEYAVSRNAIISSN
                     TSGNVIRGDESGVKWIQCGNIFVSLFHKVQDDHENDGDRIWQTLNDSLIEWKPSYYQL
                     IKSEIQNAIEAEALSFVNHLANDHYGQAAWLNEILKSDSPDIRCRNIDFVFGNLSEEL
                     YQRLKNNNTLDEFIKSVFDSYSNEYANSGVAALLQYCSSKMDLPSNNDTYHEMYHALN
                     MNLSSKNFEDGHISTGTIFFDTESNKWYLCVSAACDLVPTQGNDPHH"
BASE COUNT          308 a          189 c          146 g          329 t
ORIGIN      
        1 catggtgagg gtcgttaccc tgagtaggaa ccaaatcaca tgccgcagat acacataaat
       61 accatttgtt cgactctgta tcaaagaaaa tagtgccagt agaaatatga ccatcttcaa
      121 aattctttga agacaaattc atatttaaag catgatacat ttcgtgataa gtatcattat
      181 ttgatggcag atccattttt gaagagcaat attggagcaa tgcagcaact ccgctgttag
      241 cgtattcatt tgaatagcta tcaaaaacac ttttgataaa ttcatccagc gtattattat
      301 ttttaagtct ttgataaagc tcttctgata aattaccaaa tacaaagtca atatttctac
      361 atctaatatc aggcgagtct gattttaata tctcatttaa ccacgcagct tgaccgtaat
      421 gatcgttagc caaatgattt acaaaagata aagcctcagc ttcgattgca ttctgaattt
      481 cagattttat taactgataa taagatggtt tccattcaat gagagaatca ttgagagttt
      541 gccaaatcct atctccatcg ttttcatgat catcttgaac cttatgaaat agggagacaa
      601 agatattacc acattgaatc cattttactc cgctttcatc accccgaatg acattgccag
      661 atgtgttgct agaaataatt gcatttctag acacagcata ttctgcaatc atttttgcaa
      721 tgaagttttt atccttttga tcctccaaca cagcatcatc atgtattaat cttttaattc
      781 ttctacaagg cttactgtct ttaatatagg ctattgtttc atctcttgtg agagctttat
      841 taccattatc atttaagttc ggtaatacaa cgtcttccca ataactttgg acatcttcat
      901 tatcgtagtc aatgatcaaa ctgttgatat ccagagcacc tttgagagtc gatgatatct
      961 gcatccaaac cg
//
LOCUS       DAZUDJ010000308          971 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.313, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000308 DAZUDJ010000000
VERSION     DAZUDJ010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..971
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.313"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..269)
                     /locus_tag="ACHY1N_005466"
     CDS             complement(<1..269)
                     /locus_tag="ACHY1N_005466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030430 - host cell cytoplasm [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0046718 - symbiont entry into host cell
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HFS4047551.1"
                     /translation="MQNIHEESLNESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNE
                     KGEAVTWQGRQYQVYPIDGSGFEMNGKGSSARPSLTVSNLFGLVTG"
     gene            complement(269..610)
                     /locus_tag="ACHY1N_005467"
     CDS             complement(269..610)
                     /locus_tag="ACHY1N_005467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047552.1"
                     /translation="MAEIKTLHLVPREGMQVSEKPSVVRVRFGDGYEQRRPTGLNPQL
                     KTFQAVFRVTDESTRRWLEEFLSWHGGYRAFLWRPPKHNRTVRVVCREWSVTDNARYS
                     DFSCTIEQVVN"
     gene            complement(603..>971)
                     /locus_tag="ACHY1N_005468"
     CDS             complement(603..>971)
                     /locus_tag="ACHY1N_005468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4047553.1"
                     /translation="AVANAKGGVYTSANLSAYSNSIVDTPTYFAFAKGAGLMGEAGPE
                     AIMPLTRAADGSLGVRAVGSMNGSAGLVYSPVYHIAIQNDGTNGQIGPEAVGSLVQLI
                     DQRVQAVMLSMRRDGGMLSG"
BASE COUNT          207 a          350 c          209 g          205 t
ORIGIN      
        1 ccggtgacca gaccaaacag attggacacc gtcagcgacg gtctggcact gctgcccttc
       61 ccgttcatct caaaaccgct gccgtcaatc gggtatacct gatattgccg cccctgccag
      121 gtgaccgcct cccctttttc attcagctca ttacagaaaa aataccgctc accgccctgc
      181 accgtcaggt caatttccca gagcaccacc cgcggtgact gctctgattt aaccgactcg
      241 ttcaggcttt cttcgtgaat attctgcatc agttcaccac ctgctctatc gtgcaactga
      301 aatcactgta ccgggcatta tccgtgacac tccactcacg gcacacaacc ctcaccgtcc
      361 ggttatgttt cggcggtcgc cacaaaaagg cacggtaacc accatgccac gataaaaact
      421 cttccagcca gcgccgggtt gactcatccg tcacccggaa caccgcctga aacgtcttca
      481 gttgaggatt cagccctgtg gggcggcgct gttcataacc gtcaccaaac cgcaccctca
      541 ccaccgacgg cttctcactc acctgcatcc cttcacgcgg gaccagatgc agcgttttta
      601 tctcagccac tcagcattcc tccgtcacgt cgcatggaca gcatcaccgc ctgcacccgc
      661 tggtcaatca gctgcacaag actgcctacc gcctccggcc ctatctggcc attagtcccg
      721 tcattctgaa tggcgatatg gtagaccggg gaatacacca gacccgcact gccgttcata
      781 ctacccaccg cgcgcacacc cagcgagcca tccgccgccc gcgtcagagg cataatggct
      841 tcaggtccgg cctcccccat cagcccggcc ccttttgcaa aggcaaagta cgtgggcgta
      901 tccacaatac tgttgctgta cgcactcagg tttgccgagg tatacacgcc gccttttgca
      961 ttggccaccg c
//
LOCUS       DAZUDJ010000309          962 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.314, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000309 DAZUDJ010000000
VERSION     DAZUDJ010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.314"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            439..645
                     /locus_tag="ACHY1N_005469"
     CDS             439..645
                     /locus_tag="ACHY1N_005469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0020002 - host cell plasma membrane
                     [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA];
                     GO_process: GO:0019835 - cytolysis [Evidence IEA];
                     GO_process: GO:0044659 - viral release from host cell by
                     cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II holin family protein"
                     /protein_id="HFS4047554.1"
                     /translation="MEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGSLLF
                     GLLTYLTNLYFKIREDRRKVARGE"
BASE COUNT          259 a          174 c          259 g          270 t
ORIGIN      
        1 gccagcgact gacctgaaag aagacgctgg ctaaaaggcc ttatatgttt gtagagactt
       61 atttttcaca gacagcaatg atgcctgtca atatattatc aatatgcgga ttgtttcagt
      121 tacagatgct ttattaagga aaaaaacagc cagcactgac tttcggtgga gaggtgctgg
      181 ctcagaagga tagttggatt tcacatgata cttatgcctg gcggtatatt ttctgacaga
      241 cagtgacggg tgttgtcaag atattgtgtc atttataacc tgaatcaggg gggggccgga
      301 atgttatctg gcatttttag cagagcctga atgccataat cacggctccc ggagttggcc
      361 gtcagtgggt gacactggcg gcttttttgt ttttctttac tttcattttc tgtcggcggt
      421 gacggagaca tacatcagat ggaaaaaatc acaacaggtg tgtcatacac cacgtcagcg
      481 gtggggacgg gatactggtt actgcagctg ctggacaaag tctctccgtc ccagtgggtg
      541 gcaataggtg tgctgggaag tctgctgttt ggcctgctga cgtatctgac taacctgtat
      601 ttcaaaatca gagaggaccg tcgtaaggtg gcgcggggag agtagtcgat gaataaacaa
      661 tacgaactgg ttgtaaaatg aatatttcta actgaaaaaa cgttccatga ggtaagaaaa
      721 ggtcacaggc aatcaataac aggacgtgat gaaagaccct tgcatttgtg cgctttctct
      781 ttagatagca gcagatactg aaaatctgag ttgtcgggga gtcagggata cagctgtgca
      841 agagttggtc attgtgattc cattgaaatc ctgtatgcca tgaagggcag gattttatgg
      901 ctacctgagc tttggtgata gtaagttgaa aattcgcatt ttttgctgac atgcgtaacg
      961 ag
//
LOCUS       DAZUDJ010000310          961 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.315, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000310 DAZUDJ010000000
VERSION     DAZUDJ010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.315"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..582)
                     /locus_tag="ACHY1N_005470"
     CDS             complement(<1..582)
                     /locus_tag="ACHY1N_005470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HFS4047555.1"
                     /translation="MSTPNPLEPVKGAGTTLWVYNGQGDAYANPLSDDDWLRLAKVKD
                     LTPGEMTAEPYDDNYLDDEDADWTATGQGQKSAGDTSFTLAWKPGEEGQKGLIGWFES
                     GDVRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSKITP
                     VTAIKVTPTSGTVAKGKTTTLTVSFEPESATDKT"
     gene            complement(590..>961)
                     /locus_tag="ACHY1N_005471"
     CDS             complement(590..>961)
                     /locus_tag="ACHY1N_005471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail U family protein"
                     /protein_id="HFS4047556.1"
                     /translation="AVLDALELHEHGATLFDGRPVVFDEEDFPAVAVYLTDAEYTGEE
                     LDADTWRATLHIEVFLPAQVPDSELDSWMESRIYPAMTAIPALADLITTMVTQGYEYR
                     RDDDMALWSSADLTYSITYEM"
BASE COUNT          201 a          308 c          216 g          236 t
ORIGIN      
        1 cgtcttgtcg gttgcacttt ccggctcaaa agaaaccgtc agggtggttg ttttcccttt
       61 tgccaccgta ccggatgtcg gcgtcacctt aatcgcagtg accggcgtaa ttttgctgcg
      121 ttcttccgct acagaaggtt tgcccacgtt ggtcactttc accgtgcggg tgatcacttc
      181 tttcgccgtc acggccttac cgatactgct gacccagcca cgaaacacat ccaccgtgcc
      241 gttcggaaaa cggattttat aggcccgcac atccccgctt tcaaaccagc ctataagccc
      301 tttctgacct tcttctcccg gtttccaggc cagcgtaaaa ctggtatctc ctgcagactt
      361 ctgcccctgc ccggtcgcgg tccagtccgc gtcttcatca tccaggtagt tatcatcgta
      421 gggttctgcc gtcatctcgc ccggcgtcag atccttcacc ttagccagtc gcagccagtc
      481 atcgtctgac aacgggtttg cataggcgtc accctgaccg ttataaaccc acagggtggt
      541 accggcacct tttaccggct caaggggatt tggtgttgac atatcgtcct cacatctcgt
      601 atgtaatgga ataagtcaga tccgcagaac tccataacgc catatcgtca tcacgacgat
      661 actcatagcc ctgcgtaacc atcgtcgtaa tcaggtctgc cagtgccggg atcgcagtca
      721 tcgccggata aatccggctt tccatccacg aatccagctc cgaatccggt acctgtgctg
      781 gtaaaaacac ctcaatatgc agtgtggccc gccaggtatc tgcatccagc tcttcaccgg
      841 tatactctgc atccgtcaga taaaccgcga cggccggaaa atcctcttcg tcaaaaacaa
      901 cggggcgacc atcaaacagc gtcgccccgt gttcatgcag ctccagtgca tccagcactg
      961 c
//
LOCUS       DAZUDJ010000311          953 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.316, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000311 DAZUDJ010000000
VERSION     DAZUDJ010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..953
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.316"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..677
                     /locus_tag="ACHY1N_005472"
     CDS             <1..677
                     /locus_tag="ACHY1N_005472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001704620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4047557.1"
                     /translation="KSLNALAQLGISVEIISHELEEMDSMVTRGLNSLPTSVKEHPGF
                     SLALNAHRSLTQQIRFLSPLKISGYQSRQRITGKNIMDYVLKFFGERFERQRITIEFS
                     EEFKQIAITDIPSRIYPVFTNIINNAMYWVSLSNNRLIKIGFVNSLVIIANSGPAIDT
                     DDIPRLFELFYSKRANGHGVGLYLCRENLAVAHHKIWYLEPDEGDNYLIKDGANFVIQ
                     FNGVEF"
     gene            679..>953
                     /locus_tag="ACHY1N_005473"
     CDS             679..>953
                     /locus_tag="ACHY1N_005473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver domain"
                     /protein_id="HFS4047558.1"
                     /translation="MTVANYNSLVQKTFCENAIRSVVMIDDDFLTYSESIRALNNEVD
                     LDYNKIDSSKRAATLESFFQSKNMICDVDNGSVNFDVDRIRKSDLIIV"
BASE COUNT          305 a          154 c          185 g          309 t
ORIGIN      
        1 ctaaaagttt aaacgcgctt gcacagttag gtattagtgt tgagataata tctcatgaac
       61 ttgaagaaat ggattctatg gtaaccagag gactaaactc tcttcctact tctgtaaaag
      121 aacaccctgg tttttcattg gcgttaaatg ctcacagatc gcttactcaa caaatacgtt
      181 tcttatcacc tttgaaaata tcaggttatc aatccaggca gagaataact ggaaaaaata
      241 tcatggatta tgtcctgaag ttctttgggg agcgtttcga acggcaacga ataactattg
      301 aatttagtga agagtttaag caaatcgcaa taacagatat accatcaagg atctatcctg
      361 tttttactaa tattatcaac aatgcaatgt attgggtcag tctgtcaaat aataggctca
      421 taaagattgg ttttgtgaat tctttggtta tcatagcaaa ttctggtccg gcaattgata
      481 ccgatgatat cccgcgacta tttgaactat tttatagcaa aagagcaaat ggacatgggg
      541 taggtctgta tctatgtcga gaaaaccttg ctgttgcaca tcataaaata tggtatttag
      601 aacctgatga aggcgataac tatttaataa aagatggcgc taattttgtg atccagttca
      661 atggagtgga gttctaatat gacagtggca aattataatt ctcttgtcca gaaaactttc
      721 tgcgaaaatg caattcgttc cgttgtcatg attgatgacg attttctgac gtattctgaa
      781 tcaatcaggg cgttgaataa cgaagttgat ttagactaca acaaaattga ctcatctaaa
      841 cgagccgcta ctcttgagag cttttttcaa tctaaaaata tgatttgtga tgttgacaat
      901 ggttctgtta atttcgatgt ggatcggatt agaaaatcag atcttattat tgt
//
LOCUS       DAZUDJ010000312          950 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.317, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000312 DAZUDJ010000000
VERSION     DAZUDJ010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..950
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.317"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>950
                     /locus_tag="ACHY1N_005474"
     CDS             <1..>950
                     /locus_tag="ACHY1N_005474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HFS4047559.1"
                     /translation="ALRLSVMADIATMRMKALHFWDKHGISAASEAFGVSCRTLYWWR
                     QLLNKEGPEGLIPHSKAPLVRRKKHWHPDVLKEIRRLRTELPNLGKEQIFVRLKPWCE
                     QRYLACPSVSTIGRMIAAAHDKMRMIPVRLGSRGKALLVKKRSAKPRRPKHYRPVKTG
                     ELIGMDAIELRMGELRRYVITMIDECSNYALALAVPSLNSDIVNHFFSRAARLFPVGI
                     SQIITDNGKEFLGNFDKTLQEAAIKHLWTYPYTPKMNAICERFNRTLREQFIEFNEIL
                     LFEDLALFNQKLAEYLVLYNSKRPHKALALMTPVEYILKE"
BASE COUNT          254 a          238 c          248 g          210 t
ORIGIN      
        1 gcgttgaggc tttcagtgat ggctgatata gcaacaatga gaatgaaggc tctgcacttc
       61 tgggataaac acggtatttc tgcagcttct gaagcctttg gcgtgtcctg ccgcacgctt
      121 tactggtggc gtcagttact gaacaaggaa ggacctgagg ggctaatccc gcacagtaag
      181 gcacctctgg tgcgacgaaa aaaacactgg catcccgatg tgctgaaaga gattcgacgc
      241 ctcaggacag agctgccgaa cctcggtaaa gagcagattt ttgttcgcct gaagccctgg
      301 tgcgaacagc gctatctggc ctgtccgagt gtttccacca tcggcagaat gatcgctgcc
      361 gcacatgata aaatgcggat gatacctgtg cgtctgggat cgcgggggaa ggcactgctt
      421 gtcaaaaagc ggtctgccaa accccgcagg ccaaagcact accgcccggt aaagacaggt
      481 gagctcattg ggatggacgc cattgagctc agaatgggcg aactgcgtcg ctatgtcatc
      541 accatgatcg acgaatgcag caattacgcg ctggcgctgg ctgtgccgtc actcaacagt
      601 gatatcgtca atcacttctt cagccgcgca gcccggttgt tcccggtcgg tatcagccag
      661 ataatcacag ataacggaaa agagttcctg ggaaacttcg acaaaacgct gcaggaagcc
      721 gctatcaaac acctctggac ctatccctac acgccaaaaa tgaacgctat ctgtgaacgt
      781 tttaaccgga cgttaagaga gcagtttatt gaatttaatg agattttact ctttgaagat
      841 ctggcgctat ttaaccagaa gctggcggaa tatctggtgc tgtataacag caaaagaccc
      901 cacaaggcgc tcgcactaat gacgcccgtg gaatatattt taaaagagaa
//
LOCUS       DAZUDJ010000313          945 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.318, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000313 DAZUDJ010000000
VERSION     DAZUDJ010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.318"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(315..602)
                     /locus_tag="ACHY1N_005475"
     CDS             complement(315..602)
                     /locus_tag="ACHY1N_005475"
                     /inference="COORDINATES: protein motif:HMM:NF024728.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemagglutinin repeat-containing protein"
                     /protein_id="HFS4047560.1"
                     /translation="MGVSIGAGGNGAGISVFASVNAAKGSEKGNGTEWTETTTDSGKT
                     VTINSGRDTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGD"
     gene            complement(574..>945)
                     /locus_tag="ACHY1N_005476"
     CDS             complement(574..>945)
                     /locus_tag="ACHY1N_005476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HFS4047561.1"
                     /translation="PVQIEISPGDREGWSVVTLTALPEWPVTGSVGIDNSGQKNTGTG
                     QLNGVLSFNNPLGLADNWFVSGGRSSDFSVSHDARNFAAGISLPYGYTLVDYTYSWSD
                     YLSTIDNRGWRWRGCQYRCRW"
BASE COUNT          228 a          265 c          214 g          238 t
ORIGIN      
        1 actctgctta acggacattt ctgtataacc cttacggcaa cgaaaaacgc gaagttaaaa
       61 ttttagaaac ccaaaaacgt gacatgacta agtttagatt tcagggggga gatcaaaaaa
      121 tttcgctctg tgccagagcg gacattcatg gagctggttc attaccaatg aggttgggct
      181 tttgaggata aatcaatgat cagacgccaa cgtaaatcaa aagcaaccct ggaacggaat
      241 tgctaatcca gtttctgacc atcgattttt ctaaaaagtg tgcgtttgct actacttagg
      301 taggtgcagc tttcttaatc accggcagcc acgctggtct gtttactgtc gtacttactg
      361 gtgtcctgct ggctgcttat cagcaggtcg tggcccacat cggcgataat cctgttgccg
      421 ttgacctgag caccgttcag taccgtatcc cgaccactgt tgatggtgac ggttttaccg
      481 ctgtctgttg tggtttcagt ccactcagta ccgttacctt tctcgctgcc ttttgccgca
      541 ttaacgctgg caaagacgct gataccggca ccgttaccac cggcaccgat actgacaccc
      601 acgccaccgc cagccccggt tatcaatggt gctgaggtag tcactccatg aatacgtgta
      661 atccaccagg gtatagccat acggcagact gataccggcg gcaaaattcc tcgcatcatg
      721 tgacaccgaa aagtcactgc tccgtccccc gctgacaaac cagttgtcag ccagccccag
      781 aggattatta aaggaaagga caccatttaa ctgccccgta ccggtattct tctgcccgct
      841 gttgtcgatg cccacgctcc ctgtgactgg ccattccggc aatgccgtca gtgtcaccac
      901 cgaccatccc tcacggtcac cgggcgatat ttcaatctgt accgg
//
LOCUS       DAZUDJ010000314          944 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.319, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000314 DAZUDJ010000000
VERSION     DAZUDJ010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..944
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.319"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>944
                     /locus_tag="ACHY1N_005477"
     CDS             <1..>944
                     /locus_tag="ACHY1N_005477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047562.1"
                     /translation="TCAISQTLEEQPVLNSKSWLTSLQNDYSLPDSLTERIWLTLISQ
                     RISRGELREFELADGNWLLNNAWYERNMAGFNEQLKENLSFTPDELKTLFRNRLNLSP
                     EANDDFLDRCLDGGDWYPFSEGRRFVSFHHVDELRICASCGLTEVHHAPENHKPDPEW
                     YCSSLCRETETLCQEIYERPYNSFISDATANGLILMKLPETWSTNEKMFASGGQGHGF
                     AAERGNHIVDRVRLKNARILGDNNARNGADRLVSGTEIQTKYCSTAARSVGAAFDGQN
                     GQYRYMGNNGPMQLEVPRDQYAGAVETMRNKIREGKVPG"
BASE COUNT          264 a          226 c          246 g          208 t
ORIGIN      
        1 acctgtgcca tcagccagac actggaagaa caaccggtgc tcaacagtaa atcgtggctg
       61 accagtttgc aaaacgatta cagccttcct gactcactga cggagcgcat ctggctgacg
      121 ctcatttctc aacggatttc ccggggagag ctgagggaat ttgaactggc agacggaaac
      181 tggttactga acaatgcctg gtatgaaaga aacatggcag ggtttaacga acagttgaaa
      241 gagaacctgt cattcacacc tgatgaactg aaaacgctct tccggaaccg cctgaattta
      301 tcaccggaag cgaatgacga ttttctcgat cgttgcctgg acggcggtga ctggtatccc
      361 ttttcagaag gtcgccgttt tgtatcattc catcacgtgg atgagcttcg tatctgtgcc
      421 tcctgcgggc tgacagaagt acatcatgcc ccggaaaatc ataagccgga tccggaatgg
      481 tactgctcct ctctttgtcg cgaaacagaa acactgtgtc aggaaattta tgaacgccct
      541 tacaacagct ttatttccga tgcaacggcg aatggtctga ttctcatgaa actgccggaa
      601 acctggagta caaatgagaa aatgtttgct tccggagggc agggacatgg gtttgccgct
      661 gaacggggaa accatattgt cgacagagtc cgtctgaaaa acgcacggat cctcggtgat
      721 aataatgcca gaaatggagc agacagactg gtcagcggaa cagaaatcca gacgaaatat
      781 tgttcaactg cagcccgtag cgtcggtgcg gcattcgacg gacaaaacgg acagtatcgt
      841 tacatgggaa ataatggccc catgcaactg gaagtccccc gtgatcagta tgccggcgct
      901 gttgaaacca tgaggaataa gatccgcgaa ggtaaagtac ccgg
//
LOCUS       DAZUDJ010000315          943 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.320, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000315 DAZUDJ010000000
VERSION     DAZUDJ010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.320"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..615
                     /locus_tag="ACHY1N_005478"
     CDS             <1..615
                     /locus_tag="ACHY1N_005478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001365916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4047563.1"
                     /translation="AKIPVPADGKSITPDDVRPMIEQMVKEAVSHIPVPRDGRDYDPD
                     VLQKAVLEAVSALPAPQDGRDATALEILPAIDDQKSFPRGSYATHQGGLWRAYEKTHG
                     MRGWECLVDGVADIDVSMTGERLFSVVVRQSSGQRTEKTFSLPVMLYRGVFRAGETYH
                     PGDTVTWGGSLWHCNSMTGDKPGEAHSSGWTLAAKRGRDAGGGK"
     gene            612..938
                     /locus_tag="ACHY1N_005479"
     CDS             612..938
                     /locus_tag="ACHY1N_005479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFS4047564.1"
                     /translation="MTALLTLEEIKAHLRVDHDADDDMLMDKVRQATAVLLAYIQGSR
                     DKVIREDGELIPGEALTRMKGAAMRLTGMLYRNPDLAEREELIQGELPFSVSVLIYDL
                     RCPTVL"
BASE COUNT          204 a          227 c          322 g          190 t
ORIGIN      
        1 gcgaaaatac cggtaccggc agacggtaaa agtatcaccc ccgatgatgt gcgtccgatg
       61 attgagcaga tggtgaaaga ggcagtgagc catattcctg ttccgcgtga tggtcgtgac
      121 tacgatccgg atgttctgca gaaggcggtt ctggaggcgg tgagtgccct gccggctccg
      181 caggacgggc gtgatgccac ggcactggaa atactccccg ccattgacga tcaaaaatcc
      241 tttccccggg gctcgtatgc cacacaccag ggcggactct ggcgggcgta tgaaaaaacg
      301 cacgggatgc ggggatggga atgcctggtt gacggggtgg cggatattga cgtcagtatg
      361 acgggggagc ggttgttctc tgtggtggtc cggcagagca gtggccagcg tacggaaaaa
      421 acattttccc tgccggtgat gctctaccgc ggtgtgttca gagccggtga aacctaccac
      481 cccggcgata cggtgacgtg ggggggctcg ctgtggcact gcaacagtat gaccggtgat
      541 aaacccggag aagctcattc atcaggctgg accctggctg ccaaacgtgg acgggatgca
      601 ggaggcggaa aatgacggca ttactgacac tggaagagat caaggcacat ctgcgtgtcg
      661 accatgacgc ggatgatgac atgctgatgg acaaggttcg tcaggctacc gccgtgctgc
      721 tggcctacat tcagggcagc cgggataaag tgattcgtga ggacggtgaa ctgatcccgg
      781 gcgaggcatt aacccggatg aagggggctg ccatgcgact gaccgggatg ctgtaccgga
      841 atccggatct tgcggagcgg gaagaactga ttcaggggga gctgccgttt tctgtttccg
      901 tgctgattta cgatttgcgt tgtccgacgg tgttatgagg agg
//
LOCUS       DAZUDJ010000316          937 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.321, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000316 DAZUDJ010000000
VERSION     DAZUDJ010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..937
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.321"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            139..324
                     /locus_tag="ACHY1N_005480"
     CDS             139..324
                     /locus_tag="ACHY1N_005480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HFS4047565.1"
                     /translation="MELLLSLRIRSLIFLQKLIGRNNLTQRTRIKRLARRTIYFSRTV
                     VRNKKVIGTFIKKHIFY"
     gene            565..>937
                     /gene="nleB"
                     /locus_tag="ACHY1N_005481"
     CDS             565..>937
                     /gene="nleB"
                     /locus_tag="ACHY1N_005481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector arginine
                     glycosyltransferase NleB"
                     /protein_id="HFS4047566.1"
                     /translation="MLSSLNVLQSSFRGKTALSNSTLLQKVSFAGKEYPLEPIDEKTP
                     ILFQWFEARPERYEKGEVPILNTKEHPYLSNIINAAKIENERIIGVLVDGNFTYEQKK
                     EFLSLENEYQNIKIIYRADVDF"
BASE COUNT          326 a          159 c          170 g          282 t
ORIGIN      
        1 acaggcacat gtattttagc cccctgagtc tacagacaac caatattact taaataagtg
       61 ataatcttaa tgctgttttt tagaacagat gattgatatt tttgggccgg agaaacgcag
      121 acaggctttg ttgaataaat cgagcttttg ctgagtttaa ggatcagatc actcattttc
      181 ctgcaaaagc tcattgggcg aaacaatctg actcagagaa cccggattaa acgtctggcc
      241 cgcagaacca tctatttctc acgcactgta gtacgtaata aaaaagtcat cggtactttt
      301 atcaaaaaac atatattcta ttaattattg ccatcacctt tttcttattg acaacattac
      361 tctgctgatt gttaaaatct aacctgtatt cagggttacg attctataca atagaacagg
      421 gaggggaaag gatgtcatcg ttaatgagac tttttgttaa tgtcaacaat gctatgaatt
      481 tattttagaa aaacaattaa gctgacgtag tgttccgtct aaatgacggg gcgatattaa
      541 catgattaga acaagaggaa ttttatgtta tcttcattaa atgtccttca atccagcttc
      601 agaggaaaga cagccttatc aaatagtaca cttctccaga aagtttcttt tgctggaaaa
      661 gaatatcctc tggaacctat tgatgaaaaa acccctattc tttttcagtg gtttgaagca
      721 aggccagagc gatacgaaaa aggagaagta ccaatattga ataccaaaga acatccgtat
      781 ttgagcaata ttataaatgc tgcaaaaata gaaaatgagc gtataatcgg tgtgctggta
      841 gatggaaatt ttacttatga acaaaaaaag gaatttctca gtcttgaaaa tgaatatcaa
      901 aatataaaaa taatctaccg agcagatgtg gatttca
//
LOCUS       DAZUDJ010000317          914 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.322, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000317 DAZUDJ010000000
VERSION     DAZUDJ010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..914
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.322"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>914
                     /locus_tag="ACHY1N_005482"
     CDS             <1..>914
                     /locus_tag="ACHY1N_005482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HFS4047567.1"
                     /translation="VTRYDHDRFGQVTAVHREEGLSQYHAYDSRGQLTAVKDTQGHET
                     RYEYNIAGDLTAVIAPDGSRNGTQYDAWGKAIRTTQGGLTRSMEYDAAGRVIRLTSEN
                     GSHTTFRYDVLDRLIQETGFDGRTQRYHHDLTGKLIRSEDEGLVTHWHYDEADRLTHR
                     TVKGETAERWRYDERGWLTDISHISEGHRVTVHYGYDEKGRLTGERQTVHHPQTEALL
                     WQHETRHAYNAQGLANRCIPDSLPAVEWLTYGSGWLSGMKLGDTPLVEYTRDRLHRET
                     LRSFGRYELTTAYTPAGQLQSQHLNSLL"
BASE COUNT          217 a          282 c          282 g          133 t
ORIGIN      
        1 tgtaacccgc tatgaccatg accgttttgg tcaggtgacg gcggtgcacc gcgaggaagg
       61 cctgagccag taccacgcat acgacagccg tggacagtta actgcggtga aagacacgca
      121 gggccatgaa acgcggtatg aatacaacat cgccggtgac ctgaccgccg tcattgcccc
      181 ggacggcagc agaaacggga cacagtacga tgcgtgggga aaggccatcc gtaccacgca
      241 gggcggtctg acgcgcagta tggaatacga tgctgccgga cgggtcatcc gcctgaccag
      301 tgaaaacggc agccacacca ccttccgtta cgatgtactc gaccggctga tacaggaaac
      361 cggctttgac ggccgcacac agcgttatca ccacgacctg accggcaaac ttatccgcag
      421 cgaggatgag gggctggtca cccactggca ctatgacgaa gcagaccgcc tcacgcaccg
      481 caccgtgaag ggtgaaaccg cagagcggtg gcggtacgac gaacgcggct ggctgacaga
      541 catcagccat atcagcgaag ggcaccgggt gacggtgcat tacgggtatg atgagaaagg
      601 ccgcctgacc ggtgagcgtc agacggtgca tcacccgcag acggaagcac tgctctggca
      661 gcatgagacc agacatgcgt acaacgcgca ggggctggcg aaccgctgta taccggacag
      721 cctgcccgcc gtggaatggc tgacctacgg cagcggctgg ctgtcaggca tgaaactcgg
      781 cgacacaccg ctggtggagt acacccgcga ccgcctgcac cgggaaacgc tgcgcagctt
      841 cggccgttat gaactcacca ccgcttacac ccctgccggg cagttacaga gccagcacct
      901 gaacagcctg ctgt
//
LOCUS       DAZUDJ010000318          910 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.323, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000318 DAZUDJ010000000
VERSION     DAZUDJ010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.323"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..384
                     /locus_tag="ACHY1N_005483"
     CDS             <1..384
                     /locus_tag="ACHY1N_005483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HFS4047568.1"
                     /translation="MTFNSIQGEAPLISEAIESEIIEMAEQRQEEGTQWFNRVMGIIG
                     RGRKADDASFSRIQEAVEGVATSQADIIDRFNVLETRHQQDRQKITSLTTELAALKEK
                     LRTQDGDPQNRFTATGAASDQLADF"
     gene            408..>910
                     /locus_tag="ACHY1N_005484"
     CDS             408..>910
                     /locus_tag="ACHY1N_005484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P2 family phage major capsid protein"
                     /protein_id="HFS4047569.1"
                     /translation="MNLVMSDITRNKLGCYMAQQASLNNIPVSALVSRFTVEPSVQQR
                     FENASKESTEFTKRINVIGVTDQKGEKILLDTTGPIARTNTSYDGTKRRNPNNVVDLK
                     NRKYQCEQVNYDTFISYPQLDAWAAHPDFQSRISAQIARQVALDRIMIGFNGTSHADE
                     SNFSTNKL"
BASE COUNT          256 a          245 c          231 g          178 t
ORIGIN      
        1 atgacgttca acagtatcca gggtgaagcg ccgcttatct ccgaagccat cgagtctgaa
       61 atcatcgaaa tggcagaaca acgccaggaa gaaggcaccc agtggtttaa ccgcgtaatg
      121 gggattattg gccgtggccg caaagcggat gacgccagtt tttcccgtat tcaggaagcg
      181 gtggaaggcg tcgcaacgtc acaggccgac attatcgacc gttttaatgt gctggaaacc
      241 cgccatcagc aggaccgcca gaaaattacg tcactgacca cagagctggc agcactgaag
      301 gaaaaactgc gcacgcagga cggcgatccg cagaaccggt tcaccgcaac aggcgcagcc
      361 tccgaccagc tggctgactt ctgataagac aaaggagcaa attttttatg aatctggtga
      421 tgtcagatat tacccgcaac aagctgggtt gctatatggc gcagcaggcg tcgcttaata
      481 atattccggt ttccgcactg gtatcgcgat ttaccgtgga accctcggtg cagcagcgtt
      541 ttgaaaacgc ctcaaaggaa agcaccgaat ttacaaaaag aattaacgtg atcggcgtga
      601 ccgaccagaa aggcgaaaaa atcctcctgg acaccaccgg gccaattgca cgcacgaata
      661 ccagttatga cggcacaaaa cgccgtaacc cgaataacgt ggttgatctg aaaaaccgca
      721 aataccagtg cgaacaggtg aactacgaca cgtttatttc atatccgcag cttgatgcct
      781 gggcggcaca tcctgatttt cagtcccgca tcagcgcaca gattgcccga caggtggcgc
      841 ttgaccgcat catgatcggt ttcaacggca cgtctcacgc ggatgagtcc aacttcagca
      901 ccaacaagct
//
LOCUS       DAZUDJ010000319          906 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.324, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000319 DAZUDJ010000000
VERSION     DAZUDJ010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.324"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            266..>906
                     /locus_tag="ACHY1N_005485"
     CDS             266..>906
                     /locus_tag="ACHY1N_005485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HFS4047570.1"
                     /translation="MTFKHYDVVRAASPSDLAEKLTHKLKEGWQPFGSPVAITPYTLM
                     QAITAEGDVVVSGATEPEWYYVIVLAGQSNAMAYGEGLPLPDSYDAPDPRIKQLARRS
                     TVTPGGAACRYNDIIPADHCLHDVQDMSTLNHPKADLSKGQYGCVGQGLHIAKKLLPY
                     IPNNAGILLVPCCRGGSAFTQGAEGTFSADTGASQDSARWGVGKPLYQDLIART"
BASE COUNT          204 a          218 c          271 g          213 t
ORIGIN      
        1 aagaaaaaga atgtgcatgc aaacatgccc ctctccggag gggctttttt atgggtaaaa
       61 aatgcccgaa tgggttcggg caatagcatg agatactgat attgttgtgt tgttatcgtg
      121 tggattttaa ccagggttta tcaggctgcg caactgcgtg gccttttttc atttcttggg
      181 ctgtagtccc cgtgtgtcat tcaggcttcc ggactacagc ccactccata tctgatttaa
      241 tacactatcc cggccgggag gaataatgac atttaaacat tatgatgttg tcagggcggc
      301 gtcgccgtca gaccttgcgg aaaagctgac acacaaactg aaagagggct ggcagccgtt
      361 tggtagtccg gtggccataa ccccttatac cctgatgcag gcgattacag cagaaggtga
      421 tgtggtggtc agtggtgcaa ctgagccgga gtggtactac gtcatcgtac tggccgggca
      481 gtccaatgcc atggcttacg gtgaagggct tccgctgccg gattcatacg atgctccgga
      541 tccgcgcatt aaacagctgg cgcgccgcag tacagtgacg ccgggtgggg ctgcctgcag
      601 atataacgat attattccgg ccgaccactg cctgcatgat gtgcaggata tgagtacgct
      661 gaatcatccg aaggcagacc tgagcaaagg gcagtacggc tgtgtcggcc aggggttaca
      721 tattgccaaa aaactgctcc cgtatatccc gaataacgcg gggatcctgc tggtaccatg
      781 ctgtcgtggt ggttcggcat ttacccaggg cgcggagggg acattcagtg cggacacggg
      841 ggccagccag gattcggcgc gctggggtgt gggtaaaccg ttatatcagg acctgattgc
      901 gcgcac
//
LOCUS       DAZUDJ010000320          905 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.325, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000320 DAZUDJ010000000
VERSION     DAZUDJ010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.325"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>905
                     /locus_tag="ACHY1N_005486"
     CDS             <1..>905
                     /locus_tag="ACHY1N_005486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HFS4047571.1"
                     /translation="VDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQGY
                     PNTALVGVKVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTLKPAYSN
                     NPAWCLWDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAY
                     LTTQRKAWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFR
                     YSFSALKDRHNAVEVNWIDPNNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQA
                     HRAGLWLIKTELLETQTVDFSVGAE"
BASE COUNT          207 a          234 c          290 g          174 t
ORIGIN      
        1 ggtggataac ctgccgccgc gcccgtttaa tatccggatg cgcagaatga cgccggacag
       61 caccacagac cagctgcaga acaaaacgct ctggtcgtca tacaccgaaa tcatcgatgt
      121 gaaacagggc tacccgaaca cggcactggt cggcgtaaag gtggattcgg agcagttcgg
      181 cagccagcag gtgagccgta attatcatct tcgcgggcgt attctgcagg tgccgtcgaa
      241 ctataacccg cagacgcggc aatacagcgg tatctgggac ggaacgttaa aaccggcata
      301 cagcaacaac ccggcctggt gtctgtggga tatgctgacc cacccgcgct acggcatggg
      361 gaaacgtctt ggtgcggcgg atgtggataa atgggcgctg tatgtcatcg gccagtactg
      421 cgaccagtcg gtgccggacg gctttggcgg cacggagccg cgcattacct gtaatgcgta
      481 cctgaccaca cagcgtaagg cgtgggatgt gctcagtgat ttctgctcgg cgatgcgctg
      541 tatgccggta tggaacgggc agacgctgac gttcgtgcag gaccgaccat cagataaggt
      601 gtggacctat aaccgcagta atgtggtgat gccggatgat ggtgcgccgt tccgctacag
      661 cttcagcgcc ctgaaggacc gccataatgc cgttgaggtg aactggattg acccgaataa
      721 cggctgggag acggcgacag agcttgttga agatacgcag gccattgccc gttacggtcg
      781 taatgtcacg aagatggatg cctttggttg taccagtcgg gggcaggcac accgagccgg
      841 gctgtggctg attaaaacgg aactgctgga aacgcagacc gtggatttca gcgtgggcgc
      901 agaag
//
LOCUS       DAZUDJ010000321          895 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.326, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000321 DAZUDJ010000000
VERSION     DAZUDJ010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..895
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.326"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>895
                     /locus_tag="ACHY1N_005487"
     CDS             <1..>895
                     /locus_tag="ACHY1N_005487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcdB toxin N-terminal helical domain-containing
                     protein"
                     /protein_id="HFS4047572.1"
                     /translation="IKHSQIQEIKRNFTYKKNDDISSRFKFYSSLVKQKNSTEDVVLI
                     GKMISDEVRNYSTIHNDRNIIINSGNWKTSFLCNLARLLYSMFNGSVYFPSRDDENSS
                     SPSPTLPTIHQSERKELSQQKSINHLKKSDTIDEYIKIRKTRGIEDQITTTSQSLIIN
                     ELLNGVNRNTIPFQKISELNDIIHSYENMQTKNSRKGIEILVKQGELLSSLINYDKEN
                     KQLSDNISKIINLLGIEYQSHKVDIEPFIHAVWVAGAPPENTSSYITAFLNTYKNYTY
                     LLWIDPNAFGAAKFSGILKNIA"
BASE COUNT          371 a          141 c          132 g          251 t
ORIGIN      
        1 atcaaacata gtcaaattca agagataaaa aggaatttca cctataaaaa aaatgatgac
       61 atctcatcca gatttaaatt ttacagctcg ctagtaaagc agaaaaactc aacagaagat
      121 gttgttttga taggaaaaat gatttcagat gaagttagaa attacagcac catacataat
      181 gatagaaata tcataattaa ctctggaaat tggaaaacat cttttttatg taatcttgcc
      241 agactactat atagcatgtt taatggtagc gtctattttc cttcccgtga tgatgaaaat
      301 agctcatccc ccagcccaac tctacctact atacatcagt ctgaaaggaa ggagttatca
      361 caacaaaaaa gcatcaatca tttaaaaaaa agtgatacca tcgacgaata cattaaaata
      421 agaaaaacaa gaggcattga agatcaaata acaactacct ctcaaagttt gataattaat
      481 gagctgttaa atggagttaa tagaaatacc attccatttc agaaaataag tgagctcaat
      541 gacatcatac attcatatga aaatatgcaa actaaaaata gccgaaaagg tatagaaata
      601 ttagttaagc agggagaact gttatcatca ttaataaatt atgacaaaga aaacaaacaa
      661 ttatcagaca atatatctaa aataataaat ttattaggga tagagtatca gtcacataaa
      721 gtagacatag agccatttat acatgcagta tgggttgcag gtgcacctcc tgaaaataca
      781 tcgtcatata taacagcttt tttaaataca tataaaaatt atacttactt gctctggatt
      841 gatcccaatg cttttggtgc agccaagttt agtggaattt taaaaaatat agcca
//
LOCUS       DAZUDJ010000322          875 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.327, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000322 DAZUDJ010000000
VERSION     DAZUDJ010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..875
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.327"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>875
                     /locus_tag="ACHY1N_005488"
     CDS             <1..>875
                     /locus_tag="ACHY1N_005488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS4-like element ISVsa5 family transposase"
                     /protein_id="HFS4047573.1"
                     /translation="SFICSGNTMPIVLVDWSDISEQKRLMVLRASVALHGRSVTLYEK
                     AFPLSEQCSKKAHDQFLADLASILPSNTTPLIVSDAGFKVPWYKSVEKLGWYWLSRVR
                     GKVQYADLGAENWKPISNLHDMSSSHSKTLGYKRLTKSNPISCQILLYKSRSKGRKNQ
                     RSTRTHCHHPSPKIYSASAKEPWVLATNLPVEIRTPKQLVNIYSKRMQIEETFRDLKS
                     PAYGLGLRHSRTSSSERFDIMLLIALMLQLTCWLAGVHAQKQGWDKHFQANTVRNRNV
                     LSTVRLGMEVLRHSG"
BASE COUNT          256 a          206 c          189 g          224 t
ORIGIN      
        1 tagctttatc tgttcgggca atacgatgcc cattgtactt gttgactggt ctgatattag
       61 tgagcaaaaa cgacttatgg tattgcgagc ttcagtcgca ctacacggtc gttctgttac
      121 tctttatgag aaagcgttcc cgctttcaga gcaatgttca aagaaagctc atgaccaatt
      181 tctagccgac cttgcgagca ttctaccgag taacaccaca ccgctcattg tcagtgatgc
      241 tggctttaaa gtgccatggt ataaatccgt tgagaagctg ggttggtact ggttaagtcg
      301 agtaagagga aaagtacaat atgcagacct aggagcggaa aactggaaac ctatcagcaa
      361 cttacatgat atgtcatcta gtcactcaaa gactttaggc tataagaggc tgactaaaag
      421 caatccaatc tcatgccaaa ttctattgta taaatctcgc tctaaaggcc gaaaaaatca
      481 gcgctcgaca cggactcatt gtcaccaccc gtcacctaaa atctactcag cgtcggcaaa
      541 ggagccatgg gttctagcaa ctaacttacc tgttgaaatt cgaacaccca aacaacttgt
      601 taatatctat tcgaagcgaa tgcagattga agaaaccttc cgagacttga aaagtcctgc
      661 ctacggacta ggcctacgcc atagccgaac gagcagctca gagcgttttg atatcatgct
      721 gctaatcgcc ctgatgcttc aactaacatg ttggcttgcg ggcgttcatg ctcagaaaca
      781 aggttgggac aagcacttcc aggctaacac agtcagaaat cgaaacgtac tctcaacagt
      841 tcgcttaggc atggaagttt tgcggcattc tggct
//
LOCUS       DAZUDJ010000323          867 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.328, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000323 DAZUDJ010000000
VERSION     DAZUDJ010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.328"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            46..855
                     /locus_tag="ACHY1N_005489"
     CDS             46..855
                     /locus_tag="ACHY1N_005489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4047574.1"
                     /translation="MYWIINDNIEFWPEHRKLISVHNADLNVVLTTPASRCLSLLLEA
                     FPDVVAQQDFFTRVWEEEGMRVPTNTLYQNISIIRRGFRAVGDTTHSLIATVPRRGFK
                     IHNDTNIQNHVINSSTDAHTHNAPPAIKVNAGYKESIGGAKNFNNKILKHIKSHLIML
                     SAFVIGAYSAYWLWNNNQPKPFFKDYKTVAEINGCHFNVTEDTIDGLKEFDKYKTRIL
                     DSGINCKKHPWLYFPLAKSSPGMIVMACNKNYNQHEVADCLTLSYREVNRD"
BASE COUNT          288 a          168 c          168 g          243 t
ORIGIN      
        1 aaactatgtg atctccattt cgattgattt agtgtttatt gacgtatgta ctggattatt
       61 aacgataata tcgagttctg gcctgagcac cgaaaattaa tatcggtaca taacgccgat
      121 cttaacgtcg ttctgacaac gccagccagt cgatgtttat cacttctact tgaagctttt
      181 cctgatgtgg ttgcacaaca agattttttc accagagtct gggaagaaga aggtatgcgt
      241 gtgcctacta acacgttata tcagaacata tccattatca gacgcggatt tcgcgctgtt
      301 ggtgatacta cccactcgct aattgcaacc gtgccgagaa gaggattcaa gatccataat
      361 gacactaaca tacaaaatca tgtaataaac tcgtcaacag acgcacatac acacaatgcc
      421 ccacctgcca taaaagttaa tgcgggatac aaagagagca ttggtggcgc aaagaatttt
      481 aataacaaaa tcctcaaaca tataaaaagt catctaatta tgttgagcgc atttgtcata
      541 ggcgcatatt ctgcatattg gctatggaat aataatcaac cgaagccatt tttcaaggat
      601 tacaagactg ttgcggaaat taatggctgc cattttaatg taacagaaga tacaattgac
      661 gggttgaaag agttcgataa atataaaaca cggatactgg attcggggat taactgtaaa
      721 aaacatccgt ggttatactt ccctcttgca aaatcctcac cggggatgat tgttatggca
      781 tgcaataaaa attataacca acatgaagtg gcagactgtt taaccctgtc ttaccgtgag
      841 gttaatcgtg attgattata aaaaaaa
//
LOCUS       DAZUDJ010000324          864 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.329, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000324 DAZUDJ010000000
VERSION     DAZUDJ010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..864
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.329"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>864)
                     /locus_tag="ACHY1N_005490"
     CDS             complement(<1..>864)
                     /locus_tag="ACHY1N_005490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HFS4047575.1"
                     /translation="VDITLIYSGTHKVDGNQFEALPAEVRQDMQQRIDAARRMFAEKV
                     AMFTGLSVDAVTGTEAAVFEGQSGIDAGLADELVNASDAISVMATALNSNVRGGTMPQ
                     LTATEAAAQENQRVMGILTCQEAKGREQLATMLAGQQGMSVEQARAILAAAAPQQPVA
                     SAQSEADRIMACEEANGREQLAATLAAMPEMTVEKARPILAASPQADAGPSLRDQIMA
                     LDEAKGAEAQAEQLAACPGMTVESARAVLAAGSGKAEPVSASTTALFERIMANHSPAA
                     VQGGVPQTSADG"
BASE COUNT          148 a          297 c          226 g          193 t
ORIGIN      
        1 accgtctgct gacgtctgtg gcacgccacc ctgtaccgca gccggtgaat ggttcgccat
       61 gatgcgttca aacagggcgg ttgtggatgc agagaccggt tctgccttac ctgatcccgc
      121 agccagcaca gcccgggcgc tctccacagt cattcccggg caggcagcca gctgttcagc
      181 ctgcgcctca gccccttttg cctcatccag tgccatgatc tgatcacgga gtgagggtcc
      241 ggcatccgcc tgcggtgaag cagccaggat cgggcgggct ttttccaccg tcatctccgg
      301 catcgccgcc agcgttgccg ccagttgttc acgaccgttc gcttcttcac acgccataat
      361 gcgatcggct tcactctgcg cggatgccac cggctgctgc ggtgccgccg cggccagaat
      421 cgcccgggcc tgttcaacgc tcatgccctg ttgtcctgcc agcatcgtgg caagctgttc
      481 acgtcctttc gcttcctggc atgtcaggat ccccatcact cgctggttct cctgcgcggc
      541 ggcttccgtt gcagttaatt gcggcatagt gcctcctctg acattactgt tcagcgccgt
      601 ggccatcaca ctgatggcat ccgacgcatt gactaattca tccgccagcc cggcatcaat
      661 gccggactga ccttcaaaaa cggcggcctc tgttcccgtg acggcatcaa cagacagacc
      721 ggtaaacatc gccacttttt cggcaaacat ccggcgcgcc gcatcaatgc gctgctgcat
      781 gtcctggcga acctctgccg gtaaggcttc aaactgattg ccatccacct tgtgcgtccc
      841 tgagtaaatc agcgtgatat ccac
//
LOCUS       DAZUDJ010000325          864 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.330, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000325 DAZUDJ010000000
VERSION     DAZUDJ010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..864
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.330"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(27..740)
                     /locus_tag="ACHY1N_005491"
     CDS             complement(27..740)
                     /locus_tag="ACHY1N_005491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4047576.1"
                     /translation="MAVVCSVIMVCSPINIFLEKDTLSLKPGSVVLATKCIRELFLMH
                     YGKVKIVDISESVVSQYLESQHKLTRTRLTDIPLYLLLEPNNPALAAALITSQGFSGE
                     VTDMFLMMACLSLFETDERMSLFLSGCLSSISAKVRAIIQTDISASWTLGAIALQLHM
                     SESLLKTKLKNEGGMFSRLLLEERMRVAVNMLCSRYGYGQAVAEKCGYSSRSYFISVF
                     HRYYGFPPDRYVSRQGLDY"
BASE COUNT          276 a          213 c          157 g          218 t
ORIGIN      
        1 gtcaaaaaat aataatcaga tgaaaatcaa taatcaagcc cttgcctgga tacatatctg
       61 tctggcggga agccataata gcggtgaaat acagaaataa agtaggacct gcttgaataa
      121 ccgcattttt ctgctacagc ctgtccatat ccataccggg aacataacat atttacagca
      181 acacgcatcc gctcttccag caacaagcga ctgaacatgc ccccttcatt tttcagtttt
      241 gtctttaaca aactctcact catatgcaac tgtagagcaa tcgcaccaag cgtccagctt
      301 gctgatatat ctgtctgaat tatcgccctg actttggcac ttatgctgga taaacatcca
      361 cttaaaaaca atgacatccg ttcatctgtt tcaaacagag acaggcaggc catcataaga
      421 aacatatccg tgacctctcc ggaaaatccc tggctggtaa ttaaagccgc agccaacgca
      481 ggattgttgg gttccagcaa caggtaaagc ggaatgtcag tcagacgagt cctcgtcagc
      541 ttatgctgac tttccagata ttgacttacg acggattcgc ttatatcgac aattttaact
      601 ttgccataat gcataaggaa aagctccctg atgcatttgg tggccagaac gactgagcct
      661 ggcttaagtg acaacgtatc cttttcaaga aaaatattaa ttggggagca aaccatgata
      721 actgaacaga caacagccat tataatttta ctttcattag caattggtta gctcaattat
      781 agccccaaaa ggtaaattat catcaacaca taagcaaagg actgacaggt gtcgcccccc
      841 caccagccgc ccattcacca caaa
//
LOCUS       DAZUDJ010000326          855 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.331, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000326 DAZUDJ010000000
VERSION     DAZUDJ010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.331"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            121..>855
                     /locus_tag="ACHY1N_005492"
     CDS             121..>855
                     /locus_tag="ACHY1N_005492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001704620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047577.1"
                     /translation="MIFRDSLRVLPYGRVDNDFFQIEERRSWNAGRYYWSNRRIFGYI
                     GITQSSNKELKDKSGREGFIRNQAARELKTIISNLLTELADRFFGSRSDDRKELLEQV
                     KREKELRKSAQQQARKSTQKSFSEALKNQTPVLDASLEAVKRLKTKLDKTDGSLDLNY
                     LKIIDSDLTNLDALRSEIKTPIKPPKLGMYEEKYRDYRDKFNEFSAYILQMKLAINKL
                     DSELNKLEPSLSAKNHLEKNQGIINSK"
BASE COUNT          312 a          129 c          167 g          247 t
ORIGIN      
        1 gcaggggtcg gcccatttga gcttcagata ggaacgtttg aattcctttc acaaaataca
       61 tcacatactg aacgtgaaca ttcccacttt gatcttaagg ccaaaaagta tgcaggacta
      121 atgattttta gggatagctt gagagtatta ccttatggtc gagtagataa tgatttcttc
      181 cagatagaag aaagacgttc atggaatgca gggcgatatt attggtctaa tagaaggatt
      241 tttggttata ttggaattac tcaatccagt aataaagagc tgaaagataa gtcggggaga
      301 gagggattca taagaaacca ggctgcaaga gaactgaaaa ctattatatc taatttgtta
      361 actgaacttg ctgatagatt ttttggttca cgttctgatg accgtaaaga gcttttagaa
      421 caagttaagc gtgaaaaaga gttaagaaaa tctgctcaac aacaagctcg aaaatcaaca
      481 caaaaaagtt tttcagaagc tttgaagaat cagacaccag ttcttgatgc ttccttggag
      541 gctgttaaaa ggctgaaaac taagcttgat aaaactgatg gttcgttaga tttaaactat
      601 cttaaaatta tagacagtga tcttacaaac ttagatgcgt tgcgcagtga aattaaaacg
      661 cctatcaaac ctccaaaact tggaatgtat gaagagaaat atagagacta cagagataaa
      721 tttaatgagt tctctgcgta tattctacaa atgaagttag caattaataa acttgattct
      781 gaattaaata aacttgagcc ttcattgtca gcgaaaaatc accttgaaaa aaatcaaggt
      841 attattaatt ctaaa
//
LOCUS       DAZUDJ010000327          849 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.332, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000327 DAZUDJ010000000
VERSION     DAZUDJ010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..849
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.332"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..817
                     /locus_tag="ACHY1N_005493"
     CDS             <1..817
                     /locus_tag="ACHY1N_005493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1983 domain-containing protein"
                     /protein_id="HFS4047578.1"
                     /translation="AMWGVKIEQTKDGKHYVAGIGLSMEDAEEGKLSQFLVAANRIAF
                     IDPANGNETPMFVAQGNQIFMNDVFLKRLTAPTITSGGNPPAFSLTPDGKLTAKNADI
                     SGSVNANAGTLNNVTINENCQIKGKLSANQIEGDIVKTVGKAFPRDSRAPERWPSGTI
                     TVRVYDDQPFDRQIVIPAVAFSGAKHEREHTDIYSSCRLIVRKNGAEIYNRTALDNTL
                     IYSGVIDMPAGHGHMTLEFSVSAWLVNNWYPTASISDLLVVVMKKATAGISIS"
BASE COUNT          223 a          198 c          239 g          189 t
ORIGIN      
        1 tgccatgtgg ggcgtcaaaa ttgagcagac caaagacggc aaacattatg tcgcgggtat
       61 tggcctcagc atggaggacg cggaggaagg caaactgagc cagtttctgg ttgccgccaa
      121 tcgtatcgcg tttattgacc cggcaaacgg gaatgaaacg ccgatgtttg tggcgcaggg
      181 caaccagata ttcatgaacg acgtgttcct gaagcgcctg acggctccca ccattaccag
      241 cggcggtaat cctccggcat tttccctgac accggacgga aagctgaccg ctaaaaatgc
      301 agatatcagt ggcagtgtga atgcgaacgc cgggacgctc aacaatgtca caattaatga
      361 gaactgtcag attaagggga aactgtcagc caaccagatt gaaggcgata tagtcaaaac
      421 agtgggtaag gcttttccgc gggactcccg ggcaccggag cggtggccat cagggaccat
      481 taccgtcagg gtttatgacg atcagccgtt tgaccggcag attgttattc cggcggtggc
      541 attcagtggc gctaagcatg agagagagca tactgatatt tactcctcat gccgtctgat
      601 agtgcggaaa aacggtgctg aaatttataa ccgtaccgcg ctggataata cgctgattta
      661 cagtggcgtt attgatatgc ctgccggtca cggtcacatg acgctggagt tttcggtatc
      721 agcatggcta gtgaataact ggtatcccac agcaagtatc agcgatttgc tggttgtggt
      781 gatgaagaaa gccaccgcag gcatcagtat cagctgaatt ttataaccca tatacgggcg
      841 ccagaaatg
//
LOCUS       DAZUDJ010000328          843 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.333, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000328 DAZUDJ010000000
VERSION     DAZUDJ010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..843
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.333"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>843
                     /locus_tag="ACHY1N_005494"
     CDS             <1..>843
                     /locus_tag="ACHY1N_005494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HFS4047579.1"
                     /translation="RGAFLSAIHHQIIENQLDTETITISYEFILCQHLIANSEFSYLA
                     LPENYNRLFLPNSKNQTNNRFKTLNSKAIGRLLAAGGVYNGNIEGFRDTAEKLGGDAI
                     KGYDQILNEKTAGIAIATASILLTKRSNVDTYTEINSYLGKLRGQQKLLDGIDIIEII
                     YIKRPSKDLANLRKEFNKTVRKNFLIKLAKTSEASGRFNAEDLLRMRKGNVPLNYNVH
                     HKLSLDDGGTNDFENLVLIENEPYHKVFTNMQSRIAKGILVGESKITPWAIPSGSIYP
                     PMKN"
BASE COUNT          321 a          150 c          140 g          232 t
ORIGIN      
        1 taagaggcgc ttttttatcg gctattcatc accagatcat tgaaaaccaa ctggatacag
       61 aaacaataac tattagttat gaatttatcc tctgtcaaca tcttatcgca aattccgagt
      121 tcagctattt ggcactccct gaaaattata accgtttgtt tttaccaaat tcaaaaaacc
      181 aaacaaataa tcgtttcaaa acgttaaaca gcaaagctat tggcaggcta cttgctgctg
      241 gtggcgtata caatgggaac attgaaggat tcagagatac tgcggaaaaa ctgggtggag
      301 atgcaataaa aggctatgat caaatactaa atgaaaaaac agcgggcata gcgatagcaa
      361 cagcatctat tcttttaaca aagcgttcta atgttgatac atatacagaa ataaatagtt
      421 acttaggcaa acttagaggt caacaaaaac ttcttgatgg tatagacata atagaaataa
      481 tatacattaa gagaccttca aaagacttag ctaacttacg aaaggagttt aataaaactg
      541 taagaaaaaa ttttcttatc aaacttgcaa aaacctccga agcatctgga agattcaacg
      601 ccgaagacct tttaagaatg agaaagggca atgttcctct aaattataat gttcaccata
      661 aactatctct agatgatggt ggtactaatg atttcgaaaa tttagtatta atcgaaaacg
      721 aaccatatca taaagttttt actaacatgc aatcacgaat agctaaggga atattagtag
      781 gtgaaagcaa aatcactccc tgggccattc catctggctc aatttatcct cccatgaaaa
      841 ata
//
LOCUS       DAZUDJ010000329          838 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.334, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000329 DAZUDJ010000000
VERSION     DAZUDJ010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.334"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..760
                     /locus_tag="ACHY1N_005495"
     CDS             <1..760
                     /locus_tag="ACHY1N_005495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4047580.1"
                     /translation="AVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALDLSRLPELL
                     SRIGSYKGQPVTQLAVMLNLLVFIRSSELRYARWSEIDIDNAMWTIPAEREPLPGVKF
                     SHRGSKMRTPHLVPLSKQVVAILAELQTWAGENGLIFTGAHDPRKPISENTVNKALRV
                     MGYDTTQDVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEE
                     RRLMLQWWADFLDANRERFISPFEYAKINNPLKQ"
BASE COUNT          232 a          194 c          198 g          214 t
ORIGIN      
        1 tgccgtaatg cgttatgccg tacagtctgg catcatcaga tataatcctg ctctggatat
       61 ggctggcgca ttgactacgg taaaacgcca gcatcgcccc gctcttgatc tttctcgcct
      121 gcctgaactt ttgtcgcgta ttggcagtta caaggggcaa cctgtcaccc agcttgccgt
      181 tatgctgaat ttactggttt ttattcgttc cagtgaactc agatacgccc gctggtctga
      241 aattgatatt gacaatgcca tgtggactat tccagccgaa cgcgaacctc tgccaggcgt
      301 aaaattctca caccggggat ccaagatgcg aacaccacat cttgtgccac tcagcaaaca
      361 ggttgtagcc atactggcag aacttcagac atgggctggt gaaaatggtc tgatctttac
      421 gggagcacat gacccacgta aaccaatcag tgaaaacacc gtaaataaag ccctgagggt
      481 tatggggtat gacacaaccc aggatgtctg tggtcatgga ttccgggcga tggcatgtag
      541 tgcgttaata gaatcaggtt tgtggtcccg cgatgcagtt gaacgtcaga tgagccatca
      601 ggaacgtaac ggtgtacgtg ctgcttacat tcataaagca gaacatctgg aagaacgtcg
      661 actgatgcta cagtggtggg ccgattttct ggatgcaaac agagaaagat ttatcagtcc
      721 atttgaatat gcaaagatta ataatccatt aaaacagtaa tcatcccggg caaatgcccg
      781 ggaacctact ccaggattat tttctttgtt aaaaaaacag acaaaacggt attaactt
//
LOCUS       DAZUDJ010000330          832 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.335, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000330 DAZUDJ010000000
VERSION     DAZUDJ010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.335"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..379)
                     /locus_tag="ACHY1N_005496"
     CDS             complement(<1..379)
                     /locus_tag="ACHY1N_005496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc ribbon protein"
                     /protein_id="HFS4047581.1"
                     /translation="MYAKSFLALDGNGRLTGARTAQTAPYDRYTCHLCGSALRYHPQY
                     DTERPWFEHTDDGLTAHGQQCPYVRPERREIRLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGEQYCTNCQTGGFSIPRTT"
     gene            complement(638..>832)
                     /locus_tag="ACHY1N_005497"
     CDS             complement(638..>832)
                     /locus_tag="ACHY1N_005497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HFS4047582.1"
                     /translation="WCSALGVDAGCYATLVHFPVRPAVWLERDDETGFQQVLERAGYL
                     AKEHTKARGTGERNFGCSRS"
BASE COUNT          179 a          227 c          237 g          189 t
ORIGIN      
        1 gagttgtccg gggaatactg aatcctccgg tctggcagtt tgtgcagtac tgctccccat
       61 aataatcgtg gtgacattgt ctgcagtgcc agctggcttt acgcaccacg ggtaaggcat
      121 ccggtacgaa ttgctgcaga cgcttaatca agcgtatctc cctgcgttcc ggtctgacat
      181 aaggacactg ctgaccgtgc gctgtcagcc cgtcgtcagt gtgttcaaac cagggacgct
      241 cagtgtcgta ttgcgggtgg tatctgagtg cactgccgca aaggtggcaa gtgtagcgat
      301 cgtaaggtgc agtctgtgcg gtacgggcac ccgtcagacg cccgttgcca tcaagtgcga
      361 gaaaggattt tgcgtacata gtcatattcc tcagccgcca gacgacacgc aggcaacagc
      421 cgtcccggta cgggcagcgt ggtcaggtgt gaatggcggt tcagttaaaa tctggactgg
      481 agtttgggta aagcaggctg gttgctgtta cagcattgtg gttgtcacac aatggaacac
      541 tgacgtaaaa aacagtcagt gggcgagtgg atacatcgtt gccgccagac aacaacccat
      601 acttttggtt tgccgggtat tggcgcgtct gtcgtgttca actccggcta cagccaaagt
      661 tgcgctcacc ggtgccgcga gctttggtat gctccttcgc cagatagcca gcacgttcca
      721 gtacctgctg aaagccggtt tcatcatcgc gttccagcca caccgccggc ctgactggaa
      781 aatgcaccag cgtggcataa catccggcat ccacccccag ggcactgcac ca
//
LOCUS       DAZUDJ010000331          830 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.336, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000331 DAZUDJ010000000
VERSION     DAZUDJ010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.336"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>830)
                     /locus_tag="ACHY1N_005498"
     CDS             complement(<1..>830)
                     /locus_tag="ACHY1N_005498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase family protein"
                     /protein_id="HFS4047583.1"
                     /translation="LHDGQPDATATGKKGRAKKLKNHFTPEQIAALREKIISRLEWHQ
                     RGWFDSLTLCREAGIRNRMILKSRQIGATWYFAQEALLMALRDDVAQPYQRNQIFLSA
                     SRRQAFQFKSIIQKAAAEVDVELKGGDKIILSNGAELHFLGTSAASAQSYTGNFYFDE
                     FFWVSRFAELRKVAGAMATLSGLRRTYFSTPSTETHEAYAYWNGDRWNEKKASHKRQR
                     FSVDWETLHNGLICPDRTWRQIVTLEDVVNHGWKHTDIDEIRDENTEDEFRNLYMCEF
                     V"
BASE COUNT          183 a          235 c          207 g          205 t
ORIGIN      
        1 acaaactcac acatatagag attgcggaac tcgtcttcgg tgttttcatc acgaatttca
       61 tcaatatcgg tgtgtttcca gccgtgatta accacatctt ccagcgtgac aatttgccgc
      121 cacgtccggt cagggcagat aagcccgtta tgcagcgttt cccagtccac agaaaaacgc
      181 tggcgtttat gcgaggcctt tttctcgttc cagcggtccc cgttccagta ggcgtatgcc
      241 tcgtgcgttt cggtggatgg cgtggagaag taggtgcgcc gcagtccgct gagggttgcc
      301 atagcgccag ccaccttgcg cagttcagca aagcgactga cccagaaaaa ttcatcaaaa
      361 taaaaattgc ccgtatagga ctgtgccgac gcagcagaag tgccgagaaa atgcagttct
      421 gcgccgttgg agaggatgat tttatcgccc cctttcagct ccacatcaac ttcagccgcg
      481 gccttctgaa taatgctttt aaactggaac gcctgacgac gcgacgcaga caaaaaaatc
      541 tggttacgct ggtaaggttg cgccacatcg tcacgcagcg ccatcagcag tgcttcctgt
      601 gcaaaatacc aggtcgcccc aatctgtcgg gatttcagga tcatcctgtt acgtatcccg
      661 gcttccctgc aaagggtcag ggagtcaaac cagccccgct gatgccactc cagcctgctg
      721 atgatttttt cccgcagtgc ggcaatctgt tccggcgtga aatgattttt gagttttttc
      781 gcccggcctt tctttcctgt ggccgtcgca tccggctggc catcatgcag
//
LOCUS       DAZUDJ010000332          824 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.337, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000332 DAZUDJ010000000
VERSION     DAZUDJ010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..824
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.337"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..467)
                     /locus_tag="ACHY1N_005499"
     CDS             complement(<1..467)
                     /locus_tag="ACHY1N_005499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="contractile injection system protein, VgrG/Pvc8
                     family"
                     /protein_id="HFS4047584.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFAQVLDKMAYLTIWQGDDVQRRVKGVVTWFELGENDKNQMLYSMKVHPPLWRA
                     GLRQNFRIFQNEDIKSILGTMLQENGVTEWSPLFSEPHPSREFCVQYGETDYD"
BASE COUNT          246 a          194 c          187 g          197 t
ORIGIN      
        1 aaatcgtaat cagtctcacc gtactggaca caaaactcac gggaaggatg cggctcgctg
       61 aacagcggac tccattcggt caccccgttt tcctgcaaca tcgtgccgag gatgcttttg
      121 atgtcctcgt tctggaagat acggaagttc tggcgcagac cggcacgcca cagcggcggg
      181 tgcaccttca tgctgtacag catctggttt ttgtcgttct ccccgagttc aaaccaggtc
      241 accacgcctt tcacccggcg ctgtacgtca tcgccctgcc atatcgtcag gtaggccatt
      301 ttgtccagca cctgcgcaaa ttcaagggag agaaactgct ggctgaccag ggagagatcg
      361 agggaaaaga gcgaagagag tgactggttc agatgaaagg aaaccaccgc aaaagcgtcc
      421 ggcggcaggc cgtccacttc cagtgtgaaa cgtaatccgg ttgacatagc aacctccagt
      481 aaaatgaata atgatccgta ccgtacaact gcggataatg tgataagcgg gacgacttca
      541 gacgttatta gggaaggaac agaaaatgct atggttatgt gagaattttg tttaaatatt
      601 actttacaga aacgggtgtc tgttcagtca aaaaaataat cacaagctca acctcttgtt
      661 tcttggcgtt attcaggaca ggtacgcata tcacaacgag taacaaaaac gcaaagttaa
      721 accaatattc ataatatatt tttattcaca gcaataaata atccaattaa cattattaaa
      781 atgaatgatt gcataagaaa tatatgctac cgctccaccc tgat
//
LOCUS       DAZUDJ010000333          812 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.338, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000333 DAZUDJ010000000
VERSION     DAZUDJ010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..812
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.338"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..>812
                     /locus_tag="ACHY1N_005500"
     CDS             1..>812
                     /locus_tag="ACHY1N_005500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005091840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HFS4047585.1"
                     /translation="MSAFHNGRILVEPEPKSMRALPSGVVPAVHQPLAEDKSLLPFFS
                     DERVSRAAGGAGALSDWLLRHVKSCQWLHGDYHHSETVIHRYGTGAMVLCWHCDNQLR
                     DQTSESLEQLAHQNLSAWMIDVIGHAISGTQERELSLAELSWWAVRNQVADALPEAVL
                     RRSLGLRAEKIRSMYRESDIVPGEQTATSILKQRTKNLAPLPHAHQQQNPPQEKTVVS
                     IAVDPESPESFMKRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQG"
BASE COUNT          196 a          223 c          227 g          166 t
ORIGIN      
        1 atgtcagcat tccataacgg cagaatactg gtggagccgg aaccaaaaag catgcgagct
       61 ctgccgtccg gggttgtacc tgccgttcac cagccgctgg cggaagataa atcactactg
      121 ccatttttca gcgatgagcg ggtgagccgt gctgcgggtg gcgctggtgc actgtctgac
      181 tggttattac gtcacgtgaa atcctgccag tggctacacg gtgattatca tcacagcgaa
      241 accgtcattc accgttacgg taccggcgca atggtgttgt gctggcactg cgacaaccag
      301 ctgcgtgacc agacatccga atcactcgag caacttgctc atcaaaacct gtcagcatgg
      361 atgattgacg tcatcggtca cgcaataagc ggtacgcagg agcgtgaatt atctctggct
      421 gaattatcct ggtgggcggt ccgcaatcag gtggcggacg cgctaccgga agcggtatta
      481 cgtcgttcgc tggggttgcg tgcggaaaaa atccgctcca tgtaccgtga aagcgacatc
      541 gtaccgggag agcagaccgc caccagcata ctgaaacagc gcacaaaaaa tcttgcgccg
      601 ctgcctcacg cccaccagca acagaaccca ccacaggaaa agacggtggt cagcattgcc
      661 gttgatcctg agtctccgga atctttcatg aaacgaccta aacgtcgccg ctgggttaac
      721 gagaaataca ctcgctgggt gaagacacag ccgtgtgcgt gttgtggtaa gccagccgac
      781 gatccccatc acctgattgg tcatggtcag gg
//
LOCUS       DAZUDJ010000334          812 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.339, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000334 DAZUDJ010000000
VERSION     DAZUDJ010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..812
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.339"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            272..487
                     /locus_tag="ACHY1N_005501"
     CDS             272..487
                     /locus_tag="ACHY1N_005501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0020002 - host cell plasma membrane
                     [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA];
                     GO_process: GO:0019835 - cytolysis [Evidence IEA];
                     GO_process: GO:0044659 - viral release from host cell by
                     cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II holin family protein"
                     /protein_id="HFS4047586.1"
                     /translation="MHQMEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGS
                     LLFGLLTYLTNLYFKIKEDKRKVARGE"
     gene            complement(743..>812)
                     /locus_tag="ACHY1N_005502"
     CDS             complement(743..>812)
                     /locus_tag="ACHY1N_005502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047587.1"
                     /translation="WDSRYACQQKMRIFNLLSPKLR"
BASE COUNT          220 a          153 c          216 g          223 t
ORIGIN      
        1 cagcgcccac tctgaaggac gctggctaaa acgggtagat gtacttcaca tgatacttat
       61 atttggcagt acattttctg acagacagtg acggatgttg tcaagatatt gtgtcattta
      121 taacctgaac caggggggcc ggaatgttat ctggcatttt tagcagagcc tgaatgccat
      181 aatcacggct cccggagttg gccgtcagtg ggtgacactg gcggcttttt gttttccttt
      241 actttcattt tctgtcggcg gtgacggaga catacatcag atggaaaaaa tcacaacagg
      301 tgtgtcatac accacgtcag cggtagggac gggatactgg ttactgcaac tgctggacaa
      361 agtctctccg tcccagtggg tggcaatagg tgtgctgggg agtctgctgt ttggcctgct
      421 gacgtatctg acaaaccttt atttcaagat taaagaagat aagcgtaagg tggcgcgggg
      481 agagtagtcg atgaataaac aatacgaact ggttgtaaaa tgaatatttc taactgaaaa
      541 aacgttccat gaggtgagaa aaggtcacag gcaatcaata acaggacgtg atgaaagacc
      601 cttgcatttg tgcgctttct ctttagatag cagcagatac tgaaaatctg agttgtcggg
      661 gagtcaggga tacagctgtg caagagttgg tcattgtgat tccattgaaa tcctgtatgc
      721 catgaagggc aggattttat ggctacctga gctttggtga tagtaagttg aaaattcgca
      781 ttttttgctg acatgcgtaa cgagaatccc at
//
LOCUS       DAZUDJ010000335          792 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.340, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000335 DAZUDJ010000000
VERSION     DAZUDJ010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.340"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..80)
                     /locus_tag="ACHY1N_005503"
     CDS             complement(<1..80)
                     /locus_tag="ACHY1N_005503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047588.1"
                     /translation="MLSPIRTTFHNSVNIVQSSPCQTVSFA"
     gene            complement(257..526)
                     /locus_tag="ACHY1N_005504"
     CDS             complement(257..526)
                     /locus_tag="ACHY1N_005504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311516.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047589.1"
                     /translation="MNILRKLMERLCGCGKHDDSENGELLTAQLRLGPADILESDENG
                     IIPEQARVITQVVILDADKKQIQCVVRPLQILRADGTWENIGGMK"
     gene            complement(528..>792)
                     /locus_tag="ACHY1N_005505"
     CDS             complement(528..>792)
                     /locus_tag="ACHY1N_005505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047590.1"
                     /translation="PQGPKGDPGETQIRFRLGPASIIETNSHGWFPDTDGALITGLTF
                     LDPKDATQVQGLFRHLQVRFGDGPWQDVKGLDEVGSDTGRTGE"
BASE COUNT          179 a          242 c          153 g          218 t
ORIGIN      
        1 gcaaaagaaa ccgtttgaca gggtgaactc tgcactatat ttactgagtt atggaaagtt
       61 gtccttatcg gtgaaagcat tcgtcgtcct gtttatccat attttcttca caactaactc
      121 tttaatctat taattatatt ggcatactca accacaaaac ccccagcagt tttgccatct
      181 ttgctttcct aacaaacatc accatggcat gccaacaaaa accggagccg gactccggtt
      241 tttgtgaacc cgtcggctat ttcatcccgc caatattttc ccacgtcccg tcagcacgca
      301 ggatttgcag cggtcttacc acgcactgta tctgcttttt atccgcatcc agtatcacca
      361 cctgcgtgat taccctggcc tgctccggga taatgccatt ctcatcggac tccagaatgt
      421 ctgctggtcc cagtcgcagc tgtgctgtaa gtaactcccc gttttcactg tcatcatgct
      481 ttccgcaacc acacagacgc tccataagct ttctcaaaat attcatgtca ttctcctgtt
      541 ctgcctgtat cactgcccac ttcatccagt cccttaacat cctgccacgg cccgtcgcca
      601 aacctgacct gcaaatgccg aaacagcccc tgaacctgtg tggcatcttt ggggtcaaga
      661 aaggtcagtc cggtgatgag cgcaccatct gtatccggga accagccatg gctgtttgtc
      721 tcaataatgc tcgccggccc cagacgaaaa cggatttgtg tctcccccgg gtcgcccttc
      781 ggtccctgag gt
//
LOCUS       DAZUDJ010000336          789 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.341, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000336 DAZUDJ010000000
VERSION     DAZUDJ010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.341"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..157)
                     /locus_tag="ACHY1N_005506"
     CDS             complement(<1..157)
                     /locus_tag="ACHY1N_005506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051495 - positive regulation of
                     cytoskeleton organization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HFS4047591.1"
                     /translation="MSDTLSGTTHPDDNDDHPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRG"
     gene            complement(320..541)
                     /locus_tag="ACHY1N_005507"
     CDS             complement(320..541)
                     /locus_tag="ACHY1N_005507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HFS4047592.1"
                     /translation="MKIITRGEAMRIHRQHPASRLFPFCTGKYRWHGSAEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            complement(604..>789)
                     /locus_tag="ACHY1N_005508"
     CDS             complement(604..>789)
                     /locus_tag="ACHY1N_005508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HFS4047593.1"
                     /translation="HNAAAVVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDH
                     LIVGGSQVFSFAEHGLL"
BASE COUNT          188 a          206 c          235 g          160 t
ORIGIN      
        1 ggcctctgat accggcacgg tcggcaaggt aatgcaaccg gttaccctcc tgcaccagac
       61 gggcgccgaa acagggcgtc actgtgcagg gtagtcccca ccagggatgg tcgtcattgt
      121 catcgggatg cgttgtcccg gaaagtgtgt ctgacacgat aaaatcctca cagaaaatcg
      181 gtgaatgata gtttaacgat gacgggtcag ccggcgcgca gaccggcttc ggtaaaggtg
      241 tattcgttga tgagcaggac ctcatccaca gcggcgtctg agctcagcca gtcgtactcg
      301 ttttccgggt gacggaacat cagttcaggg tgacgctcat cagccggaca tacggaccaa
      361 aactgtcctt acggcgttct gcaaacacgg ccagcacacc gggaatatcc tgcacttcac
      421 gaccggtata cgcttcagca ctgccgtgcc agcggtattt gccggtacag aacggaaaaa
      481 gacgggatgc cggatgctga cggtgaatac gcatggcttc gccacgggtg atgattttca
      541 tagtgggata cctctgaaga cagaagataa aagtgaaaac aggtgtgatg tggttgtgac
      601 gggttaaagc agaccatgtt cggcaaagga gaaaacctgg ctgccaccga ctatcagatg
      661 gtccggcacc cggatatcca ccaggcccag tgcctgtacc agacgttccg tgataaggcg
      721 gtctgccttg ctgggtgtga cttcaccgga cgggtgattg tgtgccagca ccacagcagc
      781 ggcattgtg
//
LOCUS       DAZUDJ010000337          786 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.342, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000337 DAZUDJ010000000
VERSION     DAZUDJ010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.342"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..167
                     /locus_tag="ACHY1N_005509"
     CDS             <1..167
                     /locus_tag="ACHY1N_005509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001302295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HFS4047594.1"
                     /translation="RRTTIRNIRFPNHMIEQLNIALEHKGSGNFSAWVIEACRRRLST
                     ERSGMNYIIK"
     gene            complement(297..437)
                     /locus_tag="ACHY1N_005510"
     CDS             complement(297..437)
                     /locus_tag="ACHY1N_005510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047595.1"
                     /translation="MDFMLTVSGVVILSIAYTADKYGCHLLSRIGAYCSLMLIFSSLF
                     FE"
     gene            complement(579..>786)
                     /locus_tag="ACHY1N_005511"
     CDS             complement(579..>786)
                     /locus_tag="ACHY1N_005511"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047596.1"
                     /translation="IIHARYCRRIPALTETAARPGESSARVCGDNQKRYTPGFTALTE
                     RGVVPSWSLVRCDGGRSRMFITIN"
BASE COUNT          260 a          189 c          149 g          188 t
ORIGIN      
        1 cccgcagaac cacaatccgc aatatccgtt tccccaatca catgattgaa cagctcaata
       61 tcgcccttga acataaaggt tccggtaact tttcagcgtg ggttattgaa gcctgcagaa
      121 gaaggctgtc aacagagcgt tcgggtatga attacataat taagtaacat ggtgttcaca
      181 gaacacacag ttaccggaca catcagtttt ccattcgtcc cccggcagta caggcttccc
      241 gtctgacggg atagcctgaa aaaacacaga aaattatttg ttataattaa tataacttac
      301 tcaaaaaaaa gcgacgagaa aatcagcatc aacgagcaat aagcgccaat acgtgataac
      361 aaatggcagc catatttatc tgcagtataa gcaatggaca ggataaccac accagaaacc
      421 gtcagcataa aatccatttg aacttccccg gacaaaatcg actcatctaa agatttacag
      481 ctctttttat tatcaatatg ttaaaagtaa aataaacaga tgttcaataa tacgaataca
      541 aaaacgtgct gaaaatcaat gaatccattt ctgtgttatc aattaatagt gataaacatc
      601 cggcttcttc caccatcgca ccggaccagc gaccatgagg ggacaacgcc gcgctccgtt
      661 aacgcggtaa accccggtgt gtatcgtttt tgattatccc cgcacactcg cgcagaggat
      721 tctcccggtc gggctgcggt ctctgttaat gcaggaatac ggcgacaata ccgcgcatga
      781 ataata
//
LOCUS       DAZUDJ010000338          783 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.343, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000338 DAZUDJ010000000
VERSION     DAZUDJ010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.343"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            225..>783
                     /locus_tag="ACHY1N_005512"
     CDS             225..>783
                     /locus_tag="ACHY1N_005512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HFS4047597.1"
                     /translation="MLTTQKRKFALALMSGKNKTASAIAAGYSAKTARVKGSQLAKDP
                     EVLAFIARKQCETVEVDEVPVYRQKKSEQEDKPRRREAAAIPQPDENNPEMPPSAVMS
                     PGIEYMEDGLPDPVKAMGRLLVENINTDPRLALDAAYKLAQFTHHKKGDAGKKSAKGD
                     AAKKAANRFAVPPPPRLVVNNDNEGN"
BASE COUNT          209 a          178 c          230 g          166 t
ORIGIN      
        1 gcagagaaaa aattcccgtt tcagggcagt taacatgtta actggctgtc cgggcatttt
       61 tgcggttttt atctttatta ttcagtttgt tgtgcggaaa aaatgttaac tggctttttc
      121 agcaaatgtt aaccaggcag cagttaacat ttgcggcatg agacgccggg aaaaatgggc
      181 tgaaccatac ccggctgagt gcgttctgga cccgggagga ggctgtgctg acaacgcaaa
      241 aacgaaaatt tgcgctggcg ctcatgtccg ggaaaaacaa aacagcgtca gccattgccg
      301 ctggttattc ggcgaagacc gccagggtta aaggctcgca gctggcaaaa gatccggagg
      361 tgcttgcgtt tatagcccgt aaacaatgcg agacggtgga ggtggatgag gttcctgttt
      421 accggcagaa aaaatcagag caggaggata aaccccgtcg ccgtgaggcg gctgcaatac
      481 cacagccgga cgaaaacaat ccggagatgc caccgtccgc ggtgatgtct cctggtattg
      541 aatatatgga ggatggtctt cccgatccgg tgaaagcgat ggggcgtctt ctggtggaga
      601 acattaatac cgaccccagg ctggcgctgg atgcggctta taagctggcg cagttcacgc
      661 accataaaaa aggggatgcc ggtaaaaaat cggcaaaagg tgacgccgcg aaaaaagcgg
      721 ctaaccgttt tgcggtgcca ccaccacccc gcctggtggt gaataatgat aatgagggca
      781 acg
//
LOCUS       DAZUDJ010000339          781 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.344, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000339 DAZUDJ010000000
VERSION     DAZUDJ010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..781
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.344"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            90..>781
                     /locus_tag="ACHY1N_005513"
     CDS             90..>781
                     /locus_tag="ACHY1N_005513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4047598.1"
                     /translation="MGRKWANIVAKKTAKDGATSKIYAKFGVEIYAAAKQGEPDPELN
                     TSLKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMIIAETLTSN
                     VNRTIANVRTIFNKKGGNIGAAGSVSYMFDNTGVIVFKGTDPDHIFEILLEAEVDVRD
                     VTEEEGNIVIYTEPTDLHKGIAALKAAGITEFSTTELEMIAQSEVELSPEDLEIFEGL
                     VDALEDDDDVQKV"
BASE COUNT          258 a          133 c          171 g          219 t
ORIGIN      
        1 gatttttcct gttatgatat aatatgccga attaacacat gttaacgatt taccagtaat
       61 gtaaataaat tttcgaggag atcattccag tgggacgtaa atgggccaat attgttgcta
      121 aaaaaacggc taaagacggt gcaacgtcta aaatttatgc aaaattcggt gtagaaatct
      181 atgctgctgc taaacaaggc gaacccgatc cagaattaaa cacatcttta aaattcgtta
      241 ttgaacgtgc aaagcaggca caagttccaa agcacgttat tgataaagca attgataaag
      301 ccaaaggcgg cggagatgaa acgttcgtgc agggacgtta tgaaggcttt ggtcctaatg
      361 gctcaatgat tatcgctgag acattgactt caaatgttaa ccgtacgatt gctaacgttc
      421 gcacaatttt caataaaaaa ggcggcaata tcggagcggc aggttctgtc agctatatgt
      481 ttgacaatac gggtgtgatt gtatttaaag ggacagaccc tgaccatatt tttgaaattt
      541 tacttgaagc tgaagttgat gttcgtgatg tgactgaaga agaaggtaac attgttattt
      601 atactgaacc tactgacctt cataaaggaa tcgcggctct aaaagcagct ggaatcactg
      661 agttctcaac aacagaatta gaaatgattg ctcaatctga agttgagctt tccccagaag
      721 atttagaaat ctttgaaggg cttgttgatg cccttgaaga tgacgacgat gtacaaaaag
      781 t
//
LOCUS       DAZUDJ010000340          770 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.345, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000340 DAZUDJ010000000
VERSION     DAZUDJ010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..770
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.345"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..190)
                     /locus_tag="ACHY1N_005514"
     CDS             complement(<1..190)
                     /locus_tag="ACHY1N_005514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4047599.1"
                     /translation="MENKNHQQENFKSTYQSLVNSARILFVEKGYQAVSIDEISGKAL
                     VTKGAFYHHFKNKKQLLSA"
     gene            278..664
                     /locus_tag="ACHY1N_005515"
                     /pseudo
     CDS             278..664
                     /locus_tag="ACHY1N_005515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014656611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          240 a          124 c          149 g          257 t
ORIGIN      
        1 aggcactgag taattgtttt ttatttttaa agtgatgata aaaggcacct ttggtcacca
       61 acgcttttcc cgagatctca tctattgaaa cagcttgata gcctttttca acaaacaata
      121 ttcgtgctga gttaaccagt gattgatagg tactcttaaa attttcttgt tgatgatttt
      181 tattttccat gatagattta aaataacata ccgtcagtat gtttatggta tcatgatgat
      241 gtggtcgtga caatcttaag aacatttagg ttattttatg tatattgaac agcattctcg
      301 ctatcaaaat aaagctaata acatccaatt aagatatgat gataagcagt ttcatacaac
      361 ggttatcaaa gatgttctat tatggattga acataattta gatcagtctt tactgcttga
      421 tgatgtggcg aataaagcgg gttataccaa gtggtatttt cagcggctgt tcaaaaaagt
      481 aacaggggtc acactggcta gctatattcg tgctcgtcgt ttgacgaaag cggctgttga
      541 gttgaggttg acgaaaaaaa ctatccttga gatcgcatta aaatatcaat ttgattccca
      601 acaatctttt acacgtcgat ttaagtacat ttttaaggtt acaccaagtt attatcggcg
      661 taataaatta tgggaattgg aggcaatgca ctgagagatc ccctcataat ttccccaaag
      721 cgtaaccatg tgtgaataaa ttttgagcta gtagggttgc agccacgagt
//
LOCUS       DAZUDJ010000341          766 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.346, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000341 DAZUDJ010000000
VERSION     DAZUDJ010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.346"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(20..220)
                     /locus_tag="ACHY1N_005516"
     CDS             complement(20..220)
                     /locus_tag="ACHY1N_005516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047600.1"
                     /translation="MVIRKKKCWDCGNAITHNTVCCPYCGSVDPFGYYRNTDRIVTIL
                     LALIIVVLLTTVSVSVYILCSW"
     gene            424..>766
                     /locus_tag="ACHY1N_005517"
     CDS             424..>766
                     /locus_tag="ACHY1N_005517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HFS4047601.1"
                     /translation="MTYKYNPFWQQRIRETVRHALDVHPRLTALRVDLRLPDVPAATD
                     AAVISRFINALKARIDAYQKRKHREGKRVHSSTLHYAWAREFGELKGKKHYHLLLLVN
                     RDTWCRAGDYRA"
BASE COUNT          196 a          213 c          183 g          174 t
ORIGIN      
        1 ggatacatga accgttatct caccagctac acagtatata cacactgacg ctgacagtag
       61 tcagcaggac cacaataatc agtgccagca gtatggtaac gatacggtct gtattccggt
      121 aatagccgaa ggggtcgaca gaaccacaat acgggcaaca cacagtatta tgagtaatcg
      181 cgtttccaca gtcccagcac ttctttttgc gtatcaccat cactccctcc tcacagcctt
      241 acccgtaacc ggttttttac attaaaaaac aacgctgaaa attcaaccgt cagtccggag
      301 acgaccgttc gggttatctc agagtgcctg agatattgcc tggttggaga tcacttcagg
      361 gactctgcgc attttttacg gcgtggttaa tccgtatgaa cgaaaccata cggagattta
      421 accatgacct acaaatacaa ccccttctgg cagcaacgta ttcgtgagac ggtgcggcac
      481 gcactggatg ttcatccccg tctgacggca ttgcgggttg atctgcgtct cccggatgta
      541 ccggcagcaa cggacgcggc tgtgatatcc cgcttcatca atgccctgaa agcccgaatc
      601 gacgcttacc agaaacgtaa gcatcgggaa ggtaaacgcg tgcattcctc gaccctgcat
      661 tacgcctggg cccgggagtt cggggagctt aaaggcaaaa aacactatca cctgctgctg
      721 ctggtcaacc gggatacctg gtgtcgtgcc ggcgattacc gcgctc
//
LOCUS       DAZUDJ010000342          752 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.347, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000342 DAZUDJ010000000
VERSION     DAZUDJ010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.347"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            112..708
                     /gene="fimE"
                     /locus_tag="ACHY1N_005518"
     CDS             112..708
                     /gene="fimE"
                     /locus_tag="ACHY1N_005518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418733.1"
                     /note="upgraded from regulatory protein to switch DNA
                     invertase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimE"
                     /protein_id="HFS4047602.1"
                     /translation="MSKRRYLTGKEVQAMMQAVCYGATGARDYCLILLAYRHGMRISE
                     LLDLHYQDLDLNEGRINIRRLKNGFSTVHPLRFDEREAVERWTQERANWKGADRTDAI
                     FISRRGSRLSRQQAYRIIRDAGIEAGTVTQTHPHMLRHACGYELAERGADTRLIQDYL
                     GHRNIRHTVRYTASNAARFAGLWERNNLINEKLKREEV"
BASE COUNT          204 a          149 c          181 g          218 t
ORIGIN      
        1 gccacatcac tccgtgtgtg gttatctttt tatctattgg gctaattttg accgattgag
       61 gtttcctata ggtattcatt caaatatatc tcagttagga gtactactat tgtgagtaaa
      121 cgtcgttatc ttaccggtaa agaagttcag gccatgatgc aggcggtttg ttacggggca
      181 acgggagcca gagattattg tcttattctg ttggcatatc ggcatgggat gcgtattagt
      241 gaactgcttg atctgcatta tcaggatctt gaccttaatg aaggtcgaat aaatattcgc
      301 cgactgaaga acggattttc taccgttcac ccgttacgtt ttgatgagcg tgaagccgtg
      361 gaacgctgga cccaggaacg tgctaactgg aaaggcgctg accggaccga cgctatattt
      421 atttctcgcc gcgggagtcg gctttctcgc cagcaggcct atcgcattat tcgcgatgcc
      481 ggtattgaag ctggaaccgt aacgcagact catcctcata tgttaaggca tgcttgtggt
      541 tatgaactgg cggagcgtgg tgccgatacc cgtttaattc aggattatct cgggcatcga
      601 aatattcgcc atactgtacg ttataccgcc agtaatgctg ctcgttttgc cggactatgg
      661 gaaagaaata atctcataaa cgaaaaatta aaaagagaag aggtttgatt taactcattg
      721 ataataaagt taaaaaacaa ataaatacaa ga
//
LOCUS       DAZUDJ010000343          740 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.348, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000343 DAZUDJ010000000
VERSION     DAZUDJ010000343.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..740
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.348"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..195
                     /locus_tag="ACHY1N_005519"
     CDS             <1..195
                     /locus_tag="ACHY1N_005519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HFS4047603.1"
                     /translation="WCSALGVDVGCHATLVHFPAWPAVWLERDDDTGFQQVLERAGYL
                     AKEHTKARGTGERNFGCSRG"
     gene            362..>740
                     /locus_tag="ACHY1N_005520"
     CDS             362..>740
                     /locus_tag="ACHY1N_005520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc ribbon protein"
                     /protein_id="HFS4047604.1"
                     /translation="MYAKSFLALDGNGRLTGARTAQTAPYDRYTCHLCGSALRYHPQY
                     DTERPWFEHTDDGLTKHGHECPYVRPERREVRLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGEQYCTNCQTGGFSIPRTT"
BASE COUNT          159 a          211 c          211 g          159 t
ORIGIN      
        1 tggtgcagtg ccctgggagt ggatgtcggg tgccatgcca cgctggtgca ttttccggcc
       61 tggccggcgg tgtggctgga acgcgatgat gacactggct ttcagcaggt gctggaacgt
      121 gctggctatc tggcgaagga gcataccaaa gctcgcggca ccggtgagcg caactttggc
      181 tgcagtcgtg gctgagcccg acagacgact tatctgacct tagtgtgatg acgcgttcac
      241 agcgaccaca ctgattttcc cttctgagac tgaactgaaa accgctattc acacctgacc
      301 acgctgcccg taccgggacg gctgttgcct gcgtgtcgtc tggcggctga ggaatatgac
      361 gatgtacgca aaatcctttc tcgcacttga tggcaacggg cgtctgactg gtgcccgtac
      421 cgcacagact gcaccttacg atcgctacac ttgccacctt tgcggcagtg cactcagata
      481 ccacccgcaa tacgacactg aacgtccctg gtttgaacac actgacgacg ggctgactaa
      541 gcacggtcat gagtgccctt atgtcagacc ggaacgcagg gaggtacgct tgattaagcg
      601 tctgcagcaa ttcgtaccgg atgccttacc cgtggtgcgt aaagccagct ggcactgcag
      661 acaatgtcac cacgattatt atggggagca gtactgcaca aactgccaga ccggaggatt
      721 cagtattccc cggacaactc
//
LOCUS       DAZUDJ010000344          733 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.349, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000344 DAZUDJ010000000
VERSION     DAZUDJ010000344.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..733
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.349"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..235
                     /locus_tag="ACHY1N_005521"
                     /pseudo
     CDS             1..235
                     /locus_tag="ACHY1N_005521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_303550.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(316..474)
                     /locus_tag="ACHY1N_005522"
     CDS             complement(316..474)
                     /locus_tag="ACHY1N_005522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3927 family protein"
                     /protein_id="HFS4047605.1"
                     /translation="MFYKLCLLAVVILLLVMVMMDFTSRIMLVLTDGALVCGIVVLLW
                     PMMKEQNE"
     gene            complement(560..>733)
                     /locus_tag="ACHY1N_005523"
     CDS             complement(560..>733)
                     /locus_tag="ACHY1N_005523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308843.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047606.1"
                     /translation="KKEYEMINYNDGWYYVLARYDNCLVLSTSFNAGSKRFVIYQSAQ
                     DKNLQVDIVRTRI"
BASE COUNT          263 a          168 c          119 g          183 t
ORIGIN      
        1 taatgtttaa tcgacatcga atttctcccg tgtagaggaa cagagttaaa aagccggaag
       61 cggaatcaaa tcacaggatg accatctgcc agtggcaggt cataaaaaaa aggctgcgca
      121 atgcgcagcc agaactcaca aggaaaatga taaaaggaat aacactagtg atgtacgcat
      181 ggcgcctccc gctaagttct gcaatgatca aacagaactc gctacgtgcc cttaaaactc
      241 gatcatttag cccctccaag gaggattcac catgcggttg attttttaat aaacagtaaa
      301 caaaaaagtc aagaattatt cattctgttc tttcatcatc ggccacagca ataccacaat
      361 gccgcagacc agagcgccat cagtcagtac caacattatc ctgctggtga aatccatcat
      421 caccatcact aaaagcagga tcacaacagc aagcagacac agtttataaa acaatgttca
      481 gaaaacgcat tcagcatgcc taaggttcta ttcctacgaa tagccaactt gcaacttaaa
      541 atattattta tgcagccaat taaattctgg tccttacaat atcaacctga agattcttat
      601 cttgtgctga ttgataaatg acaaaccttt tactacctgc attgaaagaa gtagacaaaa
      661 ccagacaatt atcataacga gcaagaacat aataccaacc atcattataa ttaatcattt
      721 catattcttt ctt
//
LOCUS       DAZUDJ010000345          731 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.350, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000345 DAZUDJ010000000
VERSION     DAZUDJ010000345.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.350"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..651
                     /locus_tag="ACHY1N_005524"
     CDS             <1..651
                     /locus_tag="ACHY1N_005524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdiA-regulated domain-containing protein"
                     /protein_id="HFS4047607.1"
                     /translation="KEDDFLYATQNSPAQLLKIARSGDIIGRAPLPFISDAETIEHIQ
                     GNIFAAVDEKTSELFFFTVTKDMHISLRNKIQLEKFNKKNRGFEGLAWKAEGRMLFVA
                     KERRPTGMFAYQLSPDLLSAKQVTIPEELNDIHVKDISGLDFNNESLMILSDESRKLL
                     KFNLTEMSFVEMMDLTKGNHSLTSDLLQPEGIVTLPDESIYVASEPDILAKFVPNK"
BASE COUNT          238 a          151 c          145 g          197 t
ORIGIN      
        1 aaagaggatg atttcctgta tgccacccag aatagccctg cgcagctact taaaatagcc
       61 agaagtggcg acatcatcgg ccgagccccg ctgcctttta tctctgatgc cgaaaccatt
      121 gagcacatac aagggaacat ttttgctgca gtagacgaaa agacttctga actattcttt
      181 tttacagtta caaaagatat gcatatctcc ttgcgaaata aaattcagtt agaaaaattc
      241 aataaaaaaa atagagggtt tgaaggactg gcatggaaag cagaaggccg gatgctgttt
      301 gtcgctaaag aacgacgccc tacaggcatg tttgcctatc agctttctcc agatctgctg
      361 agtgcaaaac aagtaacgat tccagaggaa ctaaatgata tacatgttaa agatatatcc
      421 ggcctggact ttaataatga aagtctgatg attctgtccg atgaatcgcg taagttactc
      481 aagtttaacc tgacagaaat gtctttcgtt gagatgatgg acctgacaaa aggaaatcat
      541 tctctgacca gtgatttgct ccaacctgaa ggcattgtaa ctctgcctga tgaaagcatt
      601 tatgtcgcta gtgaacctga tatcctcgct aaatttgtcc ctaataaata agtctgtcac
      661 tagccttagt attgagcgac caaatctggc aatctcatga aactcgcaaa atacgaatct
      721 aatattaata a
//
LOCUS       DAZUDJ010000346          724 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.351, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000346 DAZUDJ010000000
VERSION     DAZUDJ010000346.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..724
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.351"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>724)
                     /gene="tssI"
                     /locus_tag="ACHY1N_005525"
     CDS             complement(<1..>724)
                     /gene="tssI"
                     /locus_tag="ACHY1N_005525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0033103 - protein secretion by the type VI
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein TssI/VgrG"
                     /protein_id="HFS4047608.1"
                     /translation="DQSLVLCDTVRHLPESFEIPWNPNTRTEVSTLCISQFRYSAQIR
                     PSSVVTKDYTFKRPGWAGRFEQEGQHQDYQRTQYEVYDYPGRFKSAHGQNFARWQMDG
                     WRNNAETARGMSRSPEIWPGRRIVLTGHPQANLNREWQVVASELHGEQPQAVPGRQGA
                     GTALENHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKFNWD
                     RYNPADQDSSCWIRVAQAWAGTG"
BASE COUNT          111 a          235 c          213 g          165 t
ORIGIN      
        1 aaccggtgcc tgcccacgcc tgtgccacac ggatccagca cgaactgtct tggtctgccg
       61 ggttataacg gtcccagttg aacttcaccc gcacgcgacc atgttcgtcg cagaagattt
      121 cctcgcctgc cggtcctgtc acgacagcgc tctgcgggcc gtcgaccagc ggtttcagca
      181 acggctgtgg tcgccatgtt ctgtctgccg ggatcaccgc aaaatggttc tccagcgccg
      241 tccccgctcc ctgccgtcct ggcaccgcct gtggctgttc gccgtgcagt tcacttgcca
      301 ccacctgcca ttcccggttc aggttcgcct gcggatgccc cgtcagcaca attcgccgtc
      361 ccggccatat ctccggcgag cggctcattc cccgcgcggt ttctgcgttg tttcgccagc
      421 cgtccatctg ccagcgggca aagttctgcc cgtgggcgct cttgaaacgt ccggggtagt
      481 catacacttc atactgcgtg cgctggtagt cctggtgctg gccttcctgt tcaaaacgtc
      541 cggcccagcc ggggcgttta aaggtgtagt ctttggtcac cacggaagaa gggcggattt
      601 gtgcgctgta gcggaactgg ctgatgcaga gggtgctcac ctcggtacgg gtgttcggat
      661 tccaggggat ttcaaaagat tcgggcagat ggcggactgt gtcgcacagc accaggctct
      721 ggtc
//
LOCUS       DAZUDJ010000347          720 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.352, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000347 DAZUDJ010000000
VERSION     DAZUDJ010000347.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.352"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..198
                     /gene="cbtA"
                     /locus_tag="ACHY1N_005526"
     CDS             <1..198
                     /gene="cbtA"
                     /locus_tag="ACHY1N_005526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020232068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system
                     cytoskeleton-binding toxin CbtA"
                     /protein_id="HFS4047609.1"
                     /translation="DAVNFLVEKYALVRTDQPEFSACTRSQLINSIDILRARRATGLM
                     TRDNYRTVNNITLGKYQEAKR"
     gene            195..683
                     /locus_tag="ACHY1N_005527"
     CDS             195..683
                     /locus_tag="ACHY1N_005527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5983 family protein"
                     /protein_id="HFS4047610.1"
                     /translation="MKLALTLEADSVNVQALNMGRIVVDVDGVNLTELINNVAENGYS
                     LRVVEESDQQSTCTPPPFATLAGIRCSTAHITETDNAWLYSLSHQTRDVGESEWIHFT
                     GTGYLLRTDAWSYPVLRLKRLGLSKTFRRLVVTLTRRYGVSLIHLDANAECLPGLPTF
                     DW"
BASE COUNT          180 a          194 c          179 g          167 t
ORIGIN      
        1 gatgcagtga actttcttgt tgaaaaatac gcactggtgc gtaccgacca gccggaattc
       61 agtgcctgta cccgctctca gttaataaac agcatcgata tcctccgggc tcgccgggcg
      121 actggcctga tgacccgcga caattaccga acggtaaata acattaccct gggtaagtat
      181 caggaggcga aacgatgaaa ctggccctga cgctggaagc tgacagcgtt aacgtgcagg
      241 cactgaacat ggggcgcatt gtcgttgacg tcgatggtgt taatctcact gaactgatta
      301 ataacgtcgc tgaaaacggt tattcactcc gtgtggtgga ggaatccgac caacagtcaa
      361 cctgcacacc tccgccattt gcaacccttg ccggcatacg ctgcagtacc gcacatatca
      421 cggaaacgga caacgcctgg ttgtactcgc tgtcacacca gaccagggac gttggtgaat
      481 cagaatggat tcattttaca ggtaccggtt atctgttacg tactgatgcg tggtcgtacc
      541 cggttctgcg gcttaagcgc ctgggcctgt caaaaacgtt ccgtcgtctg gttgtcacac
      601 ttacccgacg ttatggcgtc agtctcattc atctggatgc caacgctgaa tgcctgccgg
      661 gtttacccac tttcgactgg taaccagaaa caacatgaaa tcattaacca cggaaacagc
//
LOCUS       DAZUDJ010000348          720 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.353, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000348 DAZUDJ010000000
VERSION     DAZUDJ010000348.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.353"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>720)
                     /locus_tag="ACHY1N_005528"
     CDS             complement(<1..>720)
                     /locus_tag="ACHY1N_005528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1983 domain-containing protein"
                     /protein_id="HFS4047611.1"
                     /translation="YWIAASINIKPGHDYYFYIRSVNTVGKSAFVEAVGRASDDAEGY
                     LDFFKGKITESHLGKELLEKVDLTEDNASRLDEFSKEWKDANDKWNAMWGVKIEQTKD
                     GKHYVAGIGLSMEDTEEGKLSQFLVAANRIAFIDPANGNETPMFVAQGNQIFMNDVFL
                     KRLTAPTITSGGSPPVFSLTSDGKLTAKNADISGSVNANSGTLNNVTINENCQIKGKL
                     SANQIEGDIVKTVSKSFPRTS"
BASE COUNT          152 a          201 c          164 g          203 t
ORIGIN      
        1 tgctcgtgcg ggggaaagac ttgctgaccg ttttgacaat atcaccttca atctggttgg
       61 ctgacagttt ccccttaatc tgacagttct cattaatcgt gacgttgttg agcgtccctg
      121 agttcgcatt cacactgcca ctgatatccg catttttagc ggtcagcttt ccgtctgatg
      181 tcagggaaaa taccggaggg ctgccaccgc tggtaatggt gggggctgtc aggcgcttca
      241 ggaacacgtc gttcatgaat atctggttgc cctgcgccac aaacatcggc gtttcattcc
      301 cgtttgccgg gtcaataaac gcgatacggt tagcggcaac cagaaactgg ctcagcttgc
      361 cttcctccgt gtcctccatg ctgagaccaa tacccgcgac ataatgtttg ccgtctttgg
      421 tctgctcaat tttgacgccc cacatggcat tccatttatc gttagcgtcc ttccactctt
      481 tcgaaaactc atccagtctg ctggcgttat cctccgtcag atcaactttt tccagcagct
      541 ctttaccgag atgggattcg gttatcttgc ctttgaaaaa atccaggtaa ccttccgcat
      601 catcgctcgc ccgaccgacg gcctccacga atgccgattt gccaacggtg ttcacactgc
      661 ggatataaaa gtaataatca tggcccggtt tgatattgat actggcggct atccagtaca
//
LOCUS       DAZUDJ010000349          717 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.354, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000349 DAZUDJ010000000
VERSION     DAZUDJ010000349.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..717
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.354"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..195
                     /locus_tag="ACHY1N_005529"
     CDS             <1..195
                     /locus_tag="ACHY1N_005529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TA system toxin CbtA family protein"
                     /protein_id="HFS4047612.1"
                     /translation="DAVNFLVEKYALVRTDQPGFSTCPRSQLINSIDILRARRATGLM
                     TRDNYRTVNNITLGKHPEKR"
     gene            192..680
                     /locus_tag="ACHY1N_005530"
     CDS             192..680
                     /locus_tag="ACHY1N_005530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001499210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5983 family protein"
                     /protein_id="HFS4047613.1"
                     /translation="MKLSLMLEANRINVQALNMGRIVVDVDGVNLTELINKVAENGYS
                     LRVVEESDQQSTCTLPPFATLAGIRCSTAHITEKDNAWLYSLSHQTSDFGESEWIHFT
                     GSGYLLRTDAWSYPVLRLKRLGLSKTFRRLVITLTRRYGVSLIHLDASAECLPGLPTF
                     NW"
BASE COUNT          185 a          191 c          175 g          166 t
ORIGIN      
        1 gatgcggtga attttctcgt ggaaaaatac gcgctggtgc gtaccgacca gccgggattc
       61 agcacttgtc cccgctctca gttaataaac agtattgata tcctccgggc tcgccgggcg
      121 accggcctga tgacccgcga caattacaga acggtaaata acattaccct gggtaagcat
      181 ccggagaaac gatgaaactt tccctgatgc tggaagccaa cagaattaat gtgcaggcac
      241 tgaacatggg gcgaattgtc gttgacgtcg atggtgttaa tctcactgaa ctgattaaca
      301 aggtcgctga aaacggttat tcactccgcg tggtggagga atccgaccaa cagtcaacct
      361 gcacactacc accgtttgca acccttgccg gcatacgctg cagtaccgca catatcacgg
      421 aaaaggataa cgcctggctg tactcgctgt cacaccagac cagtgacttc ggtgaatcag
      481 aatggattca tttcacaggt agcggatatc tgttacgtac cgatgcgtgg tcatatccgg
      541 ttctgcggct taaacgcctg gggctgtcaa aaacgttccg tcgtctggtt atcacactta
      601 cccgacgtta tggcgtcagt ctcattcatc tggatgccag cgctgaatgc ctgccgggtt
      661 tacccacttt caactggtaa ccaggaacaa catgaaatca ttaaccacgg aaaccgc
//
LOCUS       DAZUDJ010000350          701 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.355, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000350 DAZUDJ010000000
VERSION     DAZUDJ010000350.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.355"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(1..474)
                     /locus_tag="ACHY1N_005531"
                     /pseudo
     CDS             complement(1..474)
                     /locus_tag="ACHY1N_005531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299329.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein EspS"
     gene            complement(530..701)
                     /locus_tag="ACHY1N_005532"
                     /pseudo
     CDS             complement(530..701)
                     /locus_tag="ACHY1N_005532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422669.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          187 a          147 c          135 g          232 t
ORIGIN      
        1 acttaagaag tggtagacca gcagaaccat ccccagacag ataaattttt tgtattttcc
       61 tggtgttaaa tcatctggca ggatggtttt catctctgtc gctgtaatac ttatagctgc
      121 agcagcaaca acatcgctat tatttgattg tagatggctt ttatttgctc caggatatgt
      181 aaactccatt ttccttttat caaaatcttg ttttgtagca tcattcagga ataataaatc
      241 atacggtttt ttccccgttg tgactcttga aacattttgg ccaagaatat taagagtata
      301 gtcattaacg gatttcattc ctaaaaaaac aagtaatcct tctttctctt gcgctttttc
      361 gattgttctc cctgctaaag ttattgggat ggattgagat tgttttgtcg gaactgatac
      421 gctggcgcta atataaagac ggcgcaatgg ccgccacagg ttctttctgc tcatccggcg
      481 ttatttctac aggtaataat tcaacgccag tgtcagaaga ggttgttacc ggaagacgcc
      541 gcgaaacacg cccttcgttc tgccagagcc tgagccattt gaaaataaca ttatcattga
      601 cgccattttc tcgtgcaatc tgtgcaacac aagctccagg ttgtgatgcc agttcaacca
      661 tacgaagttt gaattcattc gaatactttt tacgaggttc t
//
LOCUS       DAZUDJ010000351          697 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.356, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000351 DAZUDJ010000000
VERSION     DAZUDJ010000351.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.356"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(49..432)
                     /gene="gpFI"
                     /locus_tag="ACHY1N_005533"
     CDS             complement(49..432)
                     /gene="gpFI"
                     /locus_tag="ACHY1N_005533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001355131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HFS4047614.1"
                     /translation="MATKEENLNRLRQLAGLLGREADMSGSAADIAQRVSEWEEELAV
                     SPEGIMHSDESGADQNHTDDGEQLNNTDAPDDVKAVRVRKCLQVMGYCPETGRPVELA
                     LRGMRVLVPSSLATAMIQHGTAEYA"
     gene            complement(484..>697)
                     /locus_tag="ACHY1N_005534"
     CDS             complement(484..>697)
                     /locus_tag="ACHY1N_005534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HFS4047615.1"
                     /translation="LVLGNTAAEGIRCYGAIKDAQALSEGVVASSRYPKHWLTVGDPS
                     CEFTMTQSAPLMVLPDPDEFVVVQVK"
BASE COUNT          161 a          234 c          155 g          147 t
ORIGIN      
        1 atcgtactgt ctaccccggc gagggcagca tcaaaggcat tctgaaaatc acgcatattc
       61 agccgttccg tgctgtatca tggccgttgc cagtgatgat ggcaccagaa cacgcatacc
      121 ccgtaacgcc agctcaacgg gacgacctgt ctccgggcaa taccccatta cttgcaggca
      181 cttccgtacc cggacggctt taacatcatc cggagcatcc gtgttgttca actgctcacc
      241 atcgtctgtg tgattttgat cagccccgct ctcatcagag tgcataatgc cctccgggga
      301 aacagcaagc tcctcttccc actcagacac acgttgagca atatccgcag cactccccga
      361 catatccgcc tcgcgcccca gcaggccagc cagttgacga agacgattca gattttcttc
      421 ttttgttgcc atctcagcct cctgtgaaaa aagacacggg ggcatttcgc ccccgctcac
      481 ggattatttc acctgtacca ccacaaactc atccggatcc ggcagcacca tcagcggagc
      541 ggactgcgtc atggtgaatt cacaggacgg atcgcccacg gtcagccagt gtttcgggta
      601 acgggaagaa gccaccactc cttcagacaa cgcctgtgca tccttaatgg caccatagca
      661 acgaatcccc tctgccgccg tattccccag caccagc
//
LOCUS       DAZUDJ010000352          691 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.357, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000352 DAZUDJ010000000
VERSION     DAZUDJ010000352.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..691
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.357"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..637
                     /locus_tag="ACHY1N_005535"
     CDS             <1..637
                     /locus_tag="ACHY1N_005535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4329 domain-containing protein"
                     /protein_id="HFS4047616.1"
                     /translation="EENPHQLQQLIRLQGRYITQDPIGLKGGWNLYGYQLNPISDIDP
                     LGLSMWEDAKSGACTNGLCGTLSAMIGPDKFDSIDSTAYDALNKINSQSICEDKEFAG
                     LICKDNSGRYFSTAPNRGERKGSYPFNSPCPNGTEKVSAYHTHGADSHGEYWDEIFSG
                     KDEKIVKSKDNNIKSFYLGTPSGNFKAIDNHGKEITNRKGLPNVCRVHGNM"
     gene            609..>691
                     /locus_tag="ACHY1N_005536"
     CDS             609..>691
                     /locus_tag="ACHY1N_005536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417940.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047617.1"
                     /translation="MSAEFMVICKKILFRNCVIVSLFVFTY"
BASE COUNT          236 a          114 c          153 g          188 t
ORIGIN      
        1 tgaagagaac ccgcatcagc tgcagcagct tatccggctg caggggcgat atatcactca
       61 ggatccgatt ggactgaagg ggggatggaa cctgtatgga tatcaattga atccgatatc
      121 agacatcgac cccctgggtt tatctatgtg ggaggatgca aaatcggggg catgtactaa
      181 tggtctttgc ggcacactat ccgctatgat aggtccagat aaatttgatt ctatagatag
      241 caccgcatat gacgccttaa ataaaataaa tagccaatct atttgcgaag ataaagagtt
      301 cgctggttta atatgtaagg ataatagtgg cagatatttc tcaacagcac ctaaccgagg
      361 agaaagaaaa ggatcatatc cattcaatag cccttgccct aatggtactg agaaagtatc
      421 agcttatcat actcatggtg cagatagtca tggagaatat tgggacgaaa tattttcagg
      481 taaagatgag aaaatagtta aaagtaaaga taacaatatc aagtcatttt atttaggtac
      541 gcccagtggt aattttaaag caatagataa ccacgggaag gaaataacaa acagaaaagg
      601 attacctaat gtctgcagag ttcatggtaa tatgtaaaaa aatattgttt aggaactgtg
      661 tcattgtatc tttgtttgtt tttacataca a
//
LOCUS       DAZUDJ010000353          689 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.358, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000353 DAZUDJ010000000
VERSION     DAZUDJ010000353.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..689
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.358"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..218)
                     /locus_tag="ACHY1N_005537"
     CDS             complement(<1..218)
                     /locus_tag="ACHY1N_005537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HFS4047618.1"
                     /translation="MSIKHYDVVRAASPSDLAEKLTQKLKEGWQPFGSPVAITPYTLM
                     QAIAAEGDVTTPVLVKPSDGEGTVISAT"
     gene            195..337
                     /locus_tag="ACHY1N_005538"
                     /pseudo
     CDS             195..337
                     /locus_tag="ACHY1N_005538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_303550.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(532..645)
                     /locus_tag="ACHY1N_005539"
     CDS             complement(532..645)
                     /locus_tag="ACHY1N_005539"
                     /inference="COORDINATES: protein motif:HMM:NF024464.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3927 family protein"
                     /protein_id="HFS4047619.1"
                     /translation="MVDFTSRIMSVLADGVLVCGIVVLLWPVIKRNSLHNA"
BASE COUNT          189 a          195 c          160 g          145 t
ORIGIN      
        1 ctggtggcgc tgattactgt gccttctcca tccgacggct tcaccaacac aggtgtggtg
       61 acatcacctt ccgccgcaat ggcctgcatc agagtataag gcgtgatggc caccgggctg
      121 ccaaatggct gccacccctc cttcagtttt tgtgtcagct tttccgcaag gtctgacggc
      181 gacgccgccc tgacaacatc ataatgttta atcgacatcg aatttctccc gtgtacagga
      241 acagagttaa aaagccggaa ccggaatcaa attacaggat ggccatctgc cagtggctgg
      301 tcgtaaaaaa aggccacgcc atgcgcagcc ggaaataaag ggataacgat gatagtttga
      361 gaaaaacaga aacaacactt ttgtggcaaa gcatggtgcc gggtgcctcc cggtgaattc
      421 agtatcagca cctgaatccg cgattatccc atatacctgg ttgctgatcg cccctccgca
      481 cagggggatt caccatgcag aagtgttttt aataaacagc aaacaaaaaa atcaagcatt
      541 atgcaggctg tttcttttta tcaccggcca cagcaatacc acaatgccgc agaccagcac
      601 cccatccgcc agcaccgaca tgattctgct ggtgaaatcc accatcacca ccagaaacag
      661 caggagtgca gccacagcca ggcgcagtt
//
LOCUS       DAZUDJ010000354          681 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.359, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000354 DAZUDJ010000000
VERSION     DAZUDJ010000354.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..681
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.359"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>681
                     /locus_tag="ACHY1N_005540"
     CDS             <1..>681
                     /locus_tag="ACHY1N_005540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4765 family protein"
                     /protein_id="HFS4047620.1"
                     /translation="FVHEINNISSARWMSKSEKNNKQKEAIEKFKKEVSHMNGGQQFI
                     WGFDKVIQEGLSGLIELSIDINDSTNHRDKSSLSPDGRAVLHFLGTIWNMAMGAVPGY
                     NALSGVSSILHSAIVKESSNICDYIQGAVRIGMDFVPGTRSDLHSRSLQIKYEALKHI
                     EKNINDNIIYHPSNNANFYSVIESIDGNDFIYNEKQSKILEMKQDRGGNRYSAVDLNS
                     SKYGYYEKV"
BASE COUNT          233 a           84 c          147 g          217 t
ORIGIN      
        1 gtttgtccat gaaattaata atatatcatc tgctcgctgg atgtcaaaat cagaaaagaa
       61 taataaacaa aaagaggcaa tagaaaagtt caaaaaagaa gtatcccata tgaatggcgg
      121 gcagcagttt atttgggggt ttgataaggt tattcaagaa ggcttaagtg gattgattga
      181 gttaagtatc gatattaatg atagtacaaa tcatcgtgat aagtcttctc tttctcctga
      241 tgggagagct gtgttacatt ttttaggtac aatttggaat atggcgatgg gagctgtacc
      301 tggttataat gcattgtctg gtgtaagtag cattttacat agtgctatag taaaagaatc
      361 tagcaatatc tgtgattata ttcagggggc tgtacgtatt ggaatggact ttgttccagg
      421 cactcgctct gacttacata gccgttcgct gcagataaaa tatgaggctt tgaagcatat
      481 agaaaaaaac attaatgata atattattta tcatccgagt aataatgcta atttctattc
      541 tgtaattgag tcaattgatg gtaatgactt tatatataac gaaaaacaat ctaaaatatt
      601 agaaatgaaa caggatcgtg gggggaatag atatagtgca gtagatctta actcttctaa
      661 gtatgggtat tatgagaaag t
//
LOCUS       DAZUDJ010000355          665 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.360, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000355 DAZUDJ010000000
VERSION     DAZUDJ010000355.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..665
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.360"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>665
                     /locus_tag="ACHY1N_005541"
     CDS             <1..>665
                     /locus_tag="ACHY1N_005541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HFS4047621.1"
                     /translation="LSRHILEHLRKLTSHEPVIGIMGKSGAGKSSLCNALFQGEVTPV
                     SDVHAGTREVRRFRLSGHGHSMVITDLPGVGESRDRDAEYEALYRDILPELDLVLWLI
                     KADDRALSVDEYFWRHILHRGHQQVLFVVTQADKTEPCHEWDMAGIQPSPAQAQNIRE
                     KTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALPDHAASPLMTRLQDELRTESV
                     RSQA"
BASE COUNT          131 a          197 c          202 g          135 t
ORIGIN      
        1 ctttcccgtc acatcctgga acatctgcgc aaactcacca gtcacgaacc cgtgattggc
       61 attatgggta aaagcggggc cggtaaatcc tcactctgta atgcactgtt tcagggggag
      121 gtcaccccgg tcagtgatgt tcacgccggc acccgggaag tgcggcgctt ccgtctgagt
      181 ggccacggtc acagcatggt tatcactgac ctgcccgggg tgggcgagag ccgggacagg
      241 gatgcagagt atgaagccct gtaccgtgac attctgcccg aactggacct ggtgctgtgg
      301 ctgattaaag ccgatgaccg cgccctgtct gtggatgagt atttctggcg acacatcctg
      361 caccggggac atcagcaggt gctgtttgtg gtgacgcagg ccgacaaaac ggagccctgc
      421 catgaatggg atatggccgg tattcagcct tctcccgcac aggcacagaa tattcgcgaa
      481 aaaacggagg cggtattccg tctgttccgg cccgtacatc cggttgtggc cgtatcggcc
      541 cgcaccggct gggaactgga tacgctggtc agtgcgctca tgacagcgct tcccgaccat
      601 gccgccagtc ccctgatgac ccgcctgcag gacgagctgc gcacggaatc tgtccggtct
      661 caggc
//
LOCUS       DAZUDJ010000356          661 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.361, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000356 DAZUDJ010000000
VERSION     DAZUDJ010000356.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.361"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>661
                     /locus_tag="ACHY1N_005542"
     CDS             <1..>661
                     /locus_tag="ACHY1N_005542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HFS4047622.1"
                     /translation="RSYSYSTTGRLTGVHTTAANLDIRIPYATDPAGNRLPDPELHPD
                     STLSMWPDNRIARDAHYLYRYDRHGRLTEKTDLIPEGVIRTDDERTHRYHYDSQHRLV
                     HYTRTQYAEPLVESRYLYDPLGRRVAKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRL
                     TTIQNDRSRIQTIYQPGSFTPLIRVETATGEQAKTQRRSLADTLQQSGGEDGGSVVFP
                     PV"
BASE COUNT          149 a          211 c          203 g           98 t
ORIGIN      
        1 cggagttaca gctacagcac caccggcagg ctgaccggcg ttcacaccac cgcagcgaat
       61 ctggatatcc gcatcccgta tgccacagac ccggcaggta accgcctgcc cgacccggag
      121 ctgcacccgg acagcaccct cagcatgtgg ccggataacc gtatcgcccg tgacgcgcac
      181 tatctttacc ggtatgaccg tcacggcagg ctgacagaga aaaccgacct catcccggaa
      241 ggggttatcc gcacggatga tgagcggact caccggtacc attacgacag tcagcaccgg
      301 ctggtgcact acacgcggac acaatatgca gagccgctgg tcgaaagtcg ctatctttac
      361 gacccgctgg gccgcagggt ggcaaaacgg gtatggcgac gtgaacggga cctgacgggc
      421 tggatgtcgc tgtcacggaa accgcaagtg acctggtacg gctgggacgg cgaccggctg
      481 accacgatac agaacgacag gagccgcatc cagacgattt atcagccggg gagcttcacg
      541 ccactcatca gggttgaaac cgccaccggt gagcaggcga aaacgcagcg ccgcagcctg
      601 gcggataccc ttcagcagtc cggcggcgaa gacggtggca gtgtggtgtt cccgccggtg
      661 c
//
LOCUS       DAZUDJ010000357          658 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.362, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000357 DAZUDJ010000000
VERSION     DAZUDJ010000357.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.362"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(1..658)
                     /locus_tag="ACHY1N_005543"
                     /pseudo
     CDS             complement(1..658)
                     /locus_tag="ACHY1N_005543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309841.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="Non-LEE-encoded type III effector H"
BASE COUNT          182 a          169 c          106 g          201 t
ORIGIN      
        1 ttttccagtc tctcaaacat atcataaata gcatgctcag cctgtgctgg caaggacgaa
       61 atatttaaaa gcgattctcc atttatttta tccattctaa taccaataat atctctatta
      121 tcgccatata ttttctctgc actcccggca ccataatact ggttgaaaca acgaacttcg
      181 cttgtcacct cttcatggct ttgagatata gtaaacatct tcaacacttt tgttgtattt
      241 tccatatctt catacacgac agcattacca cctttaccaa taacgttacc tagcacgggt
      301 gatttgttgt tgctaagcct cagcaacgct gactgagtat aatccgctgg cggtaactcc
      361 ggctgcgcat aatccactgg aggtaaatca ggtctgttcg aacgaacaga tcctctttct
      421 atagtcgtgc tcactgtcga tgaattcagc atagcctcaa ttctggtgat ctctccctta
      481 ggccatccca gtctatacag catattagta aaacatccac tatgactctc tcttgtcacg
      541 caaaacctat tatcacttaa aacaacgcga tatgttctgt tgctaacctt tacttgcgcc
      601 ccattatcag agtgagcggc agcatccctt acagagggat aaaacacgat tatcaggc
//
LOCUS       DAZUDJ010000358          643 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.363, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000358 DAZUDJ010000000
VERSION     DAZUDJ010000358.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.363"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(30..308)
                     /locus_tag="ACHY1N_005544"
     CDS             complement(30..308)
                     /locus_tag="ACHY1N_005544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047623.1"
                     /translation="MAHDTKLYNSDDSAVFASRRGRCFHAFKSDWYQHPPCTEEQAEW
                     LIQCYRRRGCEVKKALSLDYRHWIISVRLPYSERPPRPSRTFQQRIWR"
     gene            complement(476..631)
                     /gene="hokD"
                     /locus_tag="ACHY1N_005545"
     CDS             complement(476..631)
                     /gene="hokD"
                     /locus_tag="ACHY1N_005545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HFS4047624.1"
                     /translation="MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRVRTGQTEVAVF
                     TAYEPEE"
BASE COUNT          140 a          165 c          186 g          152 t
ORIGIN      
        1 ccagaacagg tcgaagtaat acccgcacat tacctccaga tccgttgctg gaatgtgcgg
       61 gacggacgcg gtggccgttc ggagtaaggg agcctgacgg agattatcca gtgacggtag
      121 tcgaggctaa gggctttttt aacctcgcat ccgcgcctgc ggtaacactg aatgagccat
      181 tcggcctgtt cttcagtgca tgggggatgc tggtaccagt cagatttgaa tgcgtgaaaa
      241 caccgtccgc gcctgctggc aaagacggca gaatcatcag aattgtataa tttggtatcg
      301 tgcgccatcg gttgtctctg ctggcgcagc aggtgccagt tgttcaggct ggcgtgcgaa
      361 ttgtaaacca gaatgccagg aaaaaacaaa acccgccgaa gcgggttaag tgcgggtgcg
      421 ttgaggatgc ctgattcatc agaggtggcg agggatttct cccccgccag gtctcttact
      481 cctcaggttc gtaagctgtg aagacagcga cctccgtctg gccggttcgg actcgtacct
      541 cgcagaggtc tttcctcgtt accagtgccg tcactatgac ggttaaacag atgacgatca
      601 gggcgattaa catcgccttt tgctgcttca tagcctgctt ctc
//
LOCUS       DAZUDJ010000359          641 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.364, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000359 DAZUDJ010000000
VERSION     DAZUDJ010000359.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..641
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.364"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..254
                     /locus_tag="ACHY1N_005546"
     CDS             <1..254
                     /locus_tag="ACHY1N_005546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003796 - lysozyme activity [Evidence
                     IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA];
                     GO_process: GO:0016998 - cell wall macromolecule catabolic
                     process [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="HFS4047625.1"
                     /translation="VPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRINAGDRKGACEA
                     IRWWIKDGGRDCRIRSNNCYGQVSRRDQESALACWDIDR"
     gene            475..588
                     /locus_tag="ACHY1N_005547"
     CDS             475..588
                     /locus_tag="ACHY1N_005547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047626.1"
                     /translation="MKGIEVETPASLDLTRAAAFAIRIVAIAVLVWAIRWW"
BASE COUNT          155 a          127 c          194 g          165 t
ORIGIN      
        1 gggtgccgct gaccgaaccc cagaaagcgg ggatcgcgtc attctgtccg tacaacattg
       61 gccccggtaa gtgcttcccg tcgacgtttt ataaacgaat taatgcaggc gatcgaaaag
      121 gtgcctgtga ggcgattcgc tggtggatta aggacggtgg tagagactgc cgtatccgtt
      181 caaataattg ctacggtcag gtctcacggc gtgaccagga gagcgcgctg gcgtgctggg
      241 acatcgacag atagcagaat attttcctga aaaatgacgt tggccaacgc ggggggataa
      301 cacgaaatcc tgaaaactgg taaaacctaa gtgaataaaa gtaaaaaccc cgtttgttgg
      361 cagcaagcgg ggttttgtgt tttctgacct tgagtaaggc aagggagaaa ttatgggtag
      421 ggaggtactt tccctgtgag gaagtataaa agattctttc tgaggttgtc cattatgaaa
      481 ggcattgaag tggagacgcc agccagtctg gatttaacaa gagcggcagc ttttgccatt
      541 cgtattgtgg ccattgctgt tctggtctgg gcaatccgtt ggtggtgata tgaaccgtgt
      601 tctgtgcgtg gttatcattg tcctgctggt ggcctgtggt g
//
LOCUS       DAZUDJ010000360          636 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.365, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000360 DAZUDJ010000000
VERSION     DAZUDJ010000360.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.365"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..109
                     /locus_tag="ACHY1N_005548"
     CDS             <1..109
                     /locus_tag="ACHY1N_005548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047627.1"
                     /translation="VQGLFQHLQVRFGDGPWQDVKGLNEVGSDTGRTGE"
     gene            111..380
                     /locus_tag="ACHY1N_005549"
     CDS             111..380
                     /locus_tag="ACHY1N_005549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310967.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047628.1"
                     /translation="MNILKKLMQRLCGCGKHDGREHVQSLTAQLRLGPADILESDENG
                     IIPEQDRVITQVVILDADKKQIQCVVRPLQILRADGTWENIGGMK"
     gene            557..>636
                     /locus_tag="ACHY1N_005550"
     CDS             557..>636
                     /locus_tag="ACHY1N_005550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047629.1"
                     /translation="MLSPIRTTFHNSANIVQSSPCQTVSFA"
BASE COUNT          184 a          111 c          190 g          151 t
ORIGIN      
        1 ggttcagggg ctgtttcagc atttgcaggt caggtttggt gacgggccgt ggcaggatgt
       61 taaggggctg aatgaagtgg gcagtgatac aggcagaaca ggagaatgac atgaatatac
      121 taaaaaaact tatgcagcgt ctgtgtggtt gcggaaagca tgatggccgt gaacacgtgc
      181 agtcgcttac agcacaactg cgactgggac cggcagacat tctggagtca gatgagaatg
      241 gcattattcc ggagcaggac agggtaatca cacaggtggt gatactggat gcggataaaa
      301 agcagataca gtgcgtggta agaccgctgc aaattctgcg tgctgacggg acgtgggaaa
      361 atattggcgg gatgaagtaa cccgacagct tcacaaaacc ggagtccggc tccggttttt
      421 gttggcatgc catggtgatg tttgttagga aagcaaaggt ggcaaaactg ctggaggttt
      481 tgtggttgag tatgccaata taattaatag attaaagagt tagttgtgaa gaaaatatgg
      541 ataaacagga cgacgaatgc tttcaccgat aaggacaact ttccataact cagcaaatat
      601 agtgcagagt tcaccctgtc aaacggtttc ttttgc
//
LOCUS       DAZUDJ010000361          633 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.366, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000361 DAZUDJ010000000
VERSION     DAZUDJ010000361.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.366"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..209)
                     /locus_tag="ACHY1N_005551"
     CDS             complement(<1..209)
                     /locus_tag="ACHY1N_005551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4047630.1"
                     /translation="MSQPVGDLVIDLSLDAVRFDEQMSRVRRHFSGLDTDARKTASAV
                     EQGLSRQALAAQKAGISVGQYKAAMR"
     gene            complement(190..>633)
                     /locus_tag="ACHY1N_005552"
     CDS             complement(190..>633)
                     /locus_tag="ACHY1N_005552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HFS4047631.1"
                     /translation="LNFALRLAREMGRPDWRAMLAGMTSTEYADWRHFYRMHYFHDTQ
                     LDMHFSGLTYAVLSLFFCDPDMHPSDFSLLVPRHEEEQVERPDEDKMLMQKAAGLAGG
                     VRFGGDGGRDILSSADVADVMVDDAALMMASAGISGGVRYVPAGW"
BASE COUNT          154 a          204 c          149 g          126 t
ORIGIN      
        1 cgcatggccg ctttatactg cccgacggaa atcccggctt tttgtgcagc cagcgcctgg
       61 cggctcaggc cctgttcaac agcactggcg gtttttctgg cgtcggtatc cagacctgaa
      121 aaatgacgcc ttacccggct catctgctca tcgaaacgga ccgcatccag actaaggtca
      181 ataacaagat caccaaccgg ctgggacata tctcacacct ccggaaatcc ccgctgaagc
      241 catcattaat gcggcatcat ccaccatgac atccgccaca tccgcagacg ataaaatatc
      301 gcgccctccg tccccaccga accggacgcc tccggcaagt cctgccgctt tctgcatcag
      361 cattttgtcc tcatccggcc tctccacctg ctcttcctca tgccggggga caagcagact
      421 gaaatcagag ggatgcatat ccggatcgca aaaaaacagg ctgagtacag cgtacgtcag
      481 cccggaaaaa tgcatatcca gctgggtatc gtgaaaataa tgcatgcggt aaaaatgtcg
      541 ccagtcggca tattcggtgg atgtcatccc ggcaagcatg gcgcgccagt caggcctccc
      601 catctcacgc gccagtctga gggcaaaatt cag
//
LOCUS       DAZUDJ010000362          616 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.367, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000362 DAZUDJ010000000
VERSION     DAZUDJ010000362.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..616
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.367"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..111)
                     /locus_tag="ACHY1N_005553"
     CDS             complement(<1..111)
                     /locus_tag="ACHY1N_005553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047632.1"
                     /translation="MLQIIRGKLVIFLITLCLFVVYLGFDNNSNSDIVFYG"
     gene            complement(95..>616)
                     /locus_tag="ACHY1N_005554"
     CDS             complement(95..>616)
                     /locus_tag="ACHY1N_005554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HFS4047633.1"
                     /translation="GLRGGWNMYQYPLNPIQVIDPMGLDAIENMTSGGLIYAVSGVPG
                     LIAANSITNSAYQFGYDMDAIVGGAHNGAADAMRHCYLMCRMTKTFGSTIADVIGKNH
                     EAAGDRQGQPAKERIMDLKNNTVGIACGDFSAKCSDACIEKYNTGQLFGLDGIKADNP
                     IKAKQGSSDASNY"
BASE COUNT          185 a          149 c           94 g          188 t
ORIGIN      
        1 tccataaaat acgatgtcag aatttgaatt gttatcaaac ccaaggtaaa caacaaataa
       61 acaaagggta attaaaaaaa tgacaagttt gcctctaata atttgaagca tctgaactcc
      121 cttgctttgc ttttattgga ttatctgctt ttataccatc taacccgaag agttgcccag
      181 tgttatattt ttcaatacat gcatcgctac atttggcaga aaaatcgcca caagcaatac
      241 cgacagtgtt atttttaaga tccatgattc tttctttagc tggctgacct tgtctatccc
      301 ctgccgcctc atgattttta cctatcacgt cagctattgt tgatccaaat gtcttagtca
      361 ttcgacacat caagtaacaa tgtctcattg catcggcggc cccattatga gctccgccaa
      421 caatagcatc catatcataa ccgaactggt aagcactgtt agtaatgctg tttgcagcaa
      481 tcaatccagg tacaccagat acggcataaa ttagtccacc tgatgtcata ttctcaatcg
      541 catctaaccc cattgggtct atcacttgta tgggattcaa cggatactga tacatattcc
      601 atccacctct caaccc
//
LOCUS       DAZUDJ010000363          611 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.368, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000363 DAZUDJ010000000
VERSION     DAZUDJ010000363.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.368"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>611
                     /locus_tag="ACHY1N_005555"
     CDS             <1..>611
                     /locus_tag="ACHY1N_005555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047634.1"
                     /translation="HTPGDIIEICDNDYAGTMTGGRILSIDAASRTLTLDREVTLPET
                     GAATVNLINGSGKPVSVAITAHPAPDRIQVSTLPDGVETYGVWGLSLPSLRRRLFRCV
                     SIRENRDGTFAITAVQHVPEKEAIVDNGASFEPQSGTLNSVIPPAVQHLTVEVSAADG
                     QYLAQAKWDTPRVVKGVRFSLRLTSGSGQDSRLVTTAITADTE"
BASE COUNT          125 a          187 c          197 g          102 t
ORIGIN      
        1 cacacacccg gtgacattat tgaaatctgt gataacgact atgccgggac catgaccggc
       61 ggacgtatcc tgtccatcga tgccgccagc cgcaccctga cactggaccg tgaggtgacc
      121 ctgccggaga caggtgccgc cacggtgaac ctgattaacg gcagcggtaa gccggtgagc
      181 gtggccatca ctgcacaccc cgcgccggac cggatacagg tcagcaccct gcctgatggc
      241 gtggagacat acggtgtgtg gggactctcc ctgccgtcac tgcgtcgtcg cctgttccgc
      301 tgtgtctcca tccgggaaaa cagggacggc acctttgcca tcacggcggt gcagcacgtg
      361 ccggaaaaag aagccattgt ggataacggg gccagctttg agccgcagtc aggcaccctg
      421 aacagcgtta ttccaccggc agtgcagcac ctgacggtgg aggtgagcgc ggctgacggc
      481 cagtatctgg cgcaggcgaa atgggacacg ccgcgggtgg tgaagggcgt gcgcttcagt
      541 ctgcgcctga ccagtggaag cggtcaggac agccgtctgg tgaccaccgc catcactgcg
      601 gatacagagc a
//
LOCUS       DAZUDJ010000364          596 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.369, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000364 DAZUDJ010000000
VERSION     DAZUDJ010000364.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..596
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.369"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            41..>596
                     /locus_tag="ACHY1N_005556"
     CDS             41..>596
                     /locus_tag="ACHY1N_005556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HFS4047635.1"
                     /translation="MVAKINLLSRLTPLLFVFAPFLAQSNMTVYPMAVSINNQGEGNV
                     RVISKSNEVQYIKATVFRIDNPSTPQENEVEIKSGDANHLVVMPPKFALPAGSSKTVR
                     FVAMEPEQKEKNYRVKFEAVPSIDDVATDKKDLSMQLTVNLIWGIVVSVPPQQPIAKL
                     EVNAAQKLVNAGNQRLKILTIAYCK"
BASE COUNT          187 a          110 c          118 g          181 t
ORIGIN      
        1 caccaacttt ttggaaacaa tattgtaaga tcaaatttat atggtggcga aaattaatct
       61 cttatcacgg cttacgccgc ttttattcgt gttcgctcct tttttggcac agtcaaatat
      121 gactgtttat cctatggctg tttccattaa taatcagggt gaaggcaacg ttcgcgtaat
      181 atctaaaagt aatgaagttc agtacatcaa ggcgacagta ttccgtatcg ataatccatc
      241 gacgcctcag gaaaatgaag ttgagattaa atccggtgat gcaaatcatc tggttgttat
      301 gccacctaaa ttcgctttac cagccggtag tagcaaaacc gtacgttttg ttgcgatgga
      361 accagagcaa aaagagaaaa attatcgcgt taaatttgaa gcggttccca gtattgatga
      421 cgttgccaca gataaaaaag atctctctat gcagttaaca gttaacttaa tttgggggat
      481 tgttgttagt gttccacctc agcaacctat tgctaagtta gaagtaaatg ctgcccaaaa
      541 attagttaat gcagggaatc aacgcttaaa gattttaacg atcgcttatt gtaaaa
//
LOCUS       DAZUDJ010000365          595 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.370, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000365 DAZUDJ010000000
VERSION     DAZUDJ010000365.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.370"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..229
                     /gene="yhhH"
                     /locus_tag="ACHY1N_005557"
     CDS             <1..229
                     /gene="yhhH"
                     /locus_tag="ACHY1N_005557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417940.2"
                     /note="This BlastRule distinguishes YhhH from its paralog
                     YbbC. Both are named for founding members from Escherichia
                     coli K-12, and belong Pfam family PF15631; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein YhhH"
                     /protein_id="HFS4047636.1"
                     /translation="NLVKNKAIALELAEIYVKNRYGQDAAEEEKPYEITELTTSWVVE
                     GTIHSDQIAGGVFIIEIGKNDGRILNFGHGK"
     gene            334..>595
                     /locus_tag="ACHY1N_005558"
     CDS             334..>595
                     /locus_tag="ACHY1N_005558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lyase"
                     /protein_id="HFS4047637.1"
                     /translation="MSNTYQKRKASKEYGLYNQCKKLNDDELFRLLDDHNSLKRISSA
                     RVLQLRGGQDAVRLAIEFCSDKNYIRRDIGAFILGQIKICKKC"
BASE COUNT          220 a           80 c          136 g          159 t
ORIGIN      
        1 aaatttggtt aaaaataaag ctatagcatt ggaattagct gagatatatg ttaagaatcg
       61 ttatggacag gatgccgcag aagaagaaaa accatacgaa atcactgagt taacaacaag
      121 ttgggttgtt gaaggtacca ttcactcaga ccaaattgct ggtggggttt ttattataga
      181 aataggcaaa aatgatggga gaattctgaa ttttggccac ggaaaataag tatgtaagga
      241 taatcaaaca tcgtgtgcgc tgatggcaga gtaggtggag gactccagac agtcaaacga
      301 tagaaaaaga tagcctttat ggaggttcct gcaatgtcaa atacatacca gaaaagaaag
      361 gcaagtaaag agtatggttt atataatcaa tgtaagaaac taaatgatga tgaattattt
      421 cgcttacttg atgatcacaa ttccttgaaa aggatttcat ctgccagagt attacagtta
      481 agaggtgggc aagacgctgt tagattggca attgagttct gctctgataa aaattatatc
      541 cgtagagata tcggagcatt tatactcggg caaataaaaa tttgcaaaaa atgcg
//
LOCUS       DAZUDJ010000366          588 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.371, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000366 DAZUDJ010000000
VERSION     DAZUDJ010000366.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.371"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>588
                     /locus_tag="ACHY1N_005559"
     CDS             <1..>588
                     /locus_tag="ACHY1N_005559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047638.1"
                     /translation="MSVIDAIGEGPIEGPVKGLQSILVNKTPLTDTDGNPVIHGVTAV
                     WRAGEQEQTPPEGFESSGAETALGVEVTKAKPVTRTITSANIDRLRVTFGVQSLVQTT
                     SKGDRNPTSVRLLIQLQRNGNWVTEKDVTINGKTTSQFLASVILDNLPERPFNIRMVR
                     ETADSTPDQLQNKTLWSSYTEIIDVKQCYPNTAIVG"
BASE COUNT          140 a          160 c          186 g          102 t
ORIGIN      
        1 atgagcgtga ttgatgccat tggtgaaggg ccgattgaag gcccggtgaa ggggctgcag
       61 agtatcctgg tgaacaaaac cccgctgacg gacacggacg gcaatcctgt gatacacggt
      121 gtgaccgcgg tctggcgcgc cggggagcag gagcagacac cacctgaagg ctttgagtcc
      181 tccggggcgg aaaccgcact gggcgtggaa gtgacgaagg caaagccggt gacgcgcacc
      241 attacatccg cgaacattga ccgcctgcgg gtcaccttcg gggtgcagtc actggtgcag
      301 accacgtcaa agggtgaccg aaacccgaca tccgtccgcc tgctgattca gttacagcgt
      361 aacggtaact gggtgacgga aaaggatgtc accattaacg gcaagaccac ctcgcagttt
      421 ctggcgtcgg tgattctgga taatctgcct gagcggccct ttaacatccg gatggtccgg
      481 gagacagcgg acagcacccc ggaccagctg cagaataaga cgctctggtc gtcatacacc
      541 gaaatcatcg atgtgaaaca gtgctacccg aacacggcga ttgtgggg
//
LOCUS       DAZUDJ010000367          578 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.372, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000367 DAZUDJ010000000
VERSION     DAZUDJ010000367.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.372"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>578
                     /locus_tag="ACHY1N_005560"
     CDS             <1..>578
                     /locus_tag="ACHY1N_005560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="9-O-acetyl-N-acetylneuraminic acid deacetylase"
                     /protein_id="HFS4047639.1"
                     /translation="TNAPAEDPDIPASGYYGAASRTNGNQVSSNRPTHFSSWARRSII
                     PDRLATAILNAAGRTSAFISGKAPEIKPSPGGNTPSGPSADTSVRTISLLPAAGEAAA
                     QGWSIKDGGIQLSDGVFKITKQSNKTWSLTHPVDDAITLLTQGGRLTCKFRLSGALTN
                     NQFGLGIYLYTDAPVPDGVAMTGTGNPFLMSY"
BASE COUNT          133 a          162 c          163 g          120 t
ORIGIN      
        1 actaacgcgc cggcagaaga tccggatatt ccggcatcag gatattacgg tgcggcatcg
       61 agaacgaatg gaaaccaggt atcatcaaac cgcccgacac atttcagttc atgggcgcgc
      121 aggagcatta ttccggatcg tctggcaacc gctattctga acgcagccgg gcgcacctca
      181 gccttcatca gtggtaaggc accggaaatc aaaccctcgc ccggcggcaa cacgccatcg
      241 ggtccgtctg cagatacgtc cgttcgcaca atctccctgc tgccggcagc cggagaggct
      301 gctgcgcagg gctggagcat taaggatggc ggaattcagt tgtcagatgg tgtatttaag
      361 atcaccaagc agagcaataa aacctggtcc ctgacgcatc cggtggatga cgcaattacc
      421 ctgctgacac agggcggcag actgacctgt aagttccgcc tgtcaggcgc actgaccaac
      481 aatcagttcg ggctggggat ttatctgtat acggatgctc ccgttcctga tggtgtggcg
      541 atgacgggta ccggtaatcc gttcctgatg tcgtactt
//
LOCUS       DAZUDJ010000368          577 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.373, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000368 DAZUDJ010000000
VERSION     DAZUDJ010000368.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.373"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>577)
                     /locus_tag="ACHY1N_005561"
     CDS             complement(<1..>577)
                     /locus_tag="ACHY1N_005561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HFS4047640.1"
                     /translation="GGRSLYFEHLFPGEDGYSRSESLWLVRGGVAKLDEGHRLAALWQ
                     ALPEELRLSPHRYLATNSPQGPWWLLGWCERVPEADEVLPAPLPPYRVLTGLVDRFGR
                     TQTFHREAAGEFSGEITGVTDGAGRHFRLVLTTQAQRAEEARQQAISGGTEPSAFPDT
                     LPGYTEYGRDNGIRLSAVWLTHDPEYPENLPA"
BASE COUNT           99 a          203 c          176 g           99 t
ORIGIN      
        1 ggcaggtaaa ttctccgggt attccgggtc gtgcgtcagc cacacggcag acagacggat
       61 gccgttgtcc cggccatatt cggtgtaacc cggcagggta tcaggaaaag cggacggttc
      121 cgtcccgccg gaaatggcct gctgccgggc ttcttctgcc cgctgcgcct gcgtggtcag
      181 taccagccgg aagtgacgcc cggcaccatc cgtcacgccg gtgatttcgc cgctgaattc
      241 accggcggct tcgcggtgga acgtctgtgt gcgcccgaag cggtccacca gcccggtcag
      301 tacccggtac ggcggcagcg gcgcaggcag cacctcatcc gcttccggca cccgctcaca
      361 ccagccgagc agccaccacg gcccctgcgg actgtttgtc gccagataac gatgcggact
      421 taagcggagt tcttccggca gcgcctgcca gagtgcggcc agccggtgac cttcatccag
      481 tttcgccacg ccgccgcgca ccagccacag tgactcgctg cggctgtaac cgtcctcacc
      541 gggaaacagg tgctcaaaat acaggcttct gccgccg
//
LOCUS       DAZUDJ010000369          577 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.374, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000369 DAZUDJ010000000
VERSION     DAZUDJ010000369.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.374"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..368
                     /locus_tag="ACHY1N_005562"
     CDS             <1..368
                     /locus_tag="ACHY1N_005562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030257 - type III protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0030254 - protein secretion by the type III
                     secretion system [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="type III secretion apparatus protein OrgA/MxiK"
                     /protein_id="HFS4047641.1"
                     /translation="LFSGYHFYRERFAERGFFYKVPAVLRDYLSAIPVKINEKARYKP
                     GIASYHNIITCGFSTLSPYIRQQPLAMQQRFNLLFPDFVDHIQLPLPLASTLLERITF
                     YAKKNRDELDKISCKWCCD"
     gene            397..>577
                     /locus_tag="ACHY1N_005563"
     CDS             397..>577
                     /locus_tag="ACHY1N_005563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047642.1"
                     /translation="MVSLKESILLETSAKIQSIEVKREEKFIQGYYDGYTKGIIDVMD
                     NFIPLISLLSSELEKK"
BASE COUNT          201 a           88 c          107 g          181 t
ORIGIN      
        1 gtttattcag tggttatcac ttttatcgag aaaggtttgc agaacgcgga tttttttata
       61 aggttcctgc tgtgctaagg gattatttat cagctatacc ggtgaaaata aatgaaaagg
      121 cacgatacaa acccggcatc gctagctatc acaatatcat cacatgtggt ttttcaacgt
      181 tgtcacccta tataaggcaa caaccattgg caatgcagca acgatttaat ttattatttc
      241 ctgattttgt tgatcacata caattgccgt taccacttgc atcaactctt ttagagagaa
      301 ttacatttta tgcgaaaaaa aatagagatg agcttgataa aatctcctgc aaatggtgtt
      361 gtgattaaaa gaaaaatttc tgatggattg aaataaatag tttctcttaa agaaagtatc
      421 cttcttgaaa ccagcgcaaa aattcagagc attgaggtaa agagagaaga aaaatttatt
      481 caaggttatt atgatggcta tacaaaaggc attattgatg tgatggataa ttttataccc
      541 ttgataagct tgttgagctc agaactagaa aaaaaag
//
LOCUS       DAZUDJ010000370          575 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.375, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000370 DAZUDJ010000000
VERSION     DAZUDJ010000370.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.375"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..549
                     /locus_tag="ACHY1N_005564"
     CDS             <1..549
                     /locus_tag="ACHY1N_005564"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000044123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4047643.1"
                     /translation="IRHSLNIINDDSLILSVGRLTDAKDYPNLLKALLELPERYKLVI
                     IGEGEARNEVERTILNYGLEKRVKLLGSIANVATYYSACDIYVSSSKWEGFGLVVAEA
                     MSCQRLVVATNAGGVAEVVGDMNYIVPVSDPQLLANKINEVMEFDHETKMEVMYRNRE
                     FVLKMFSIDMIVNQWMKLYSSI"
BASE COUNT          187 a           74 c          125 g          189 t
ORIGIN      
        1 ataaggcata gtttaaatat cattaatgat gatagcctta tactttctgt aggccgactt
       61 actgatgcaa aagattatcc aaacttatta aaagcattgt tagaattacc tgaacgatat
      121 aaattagtca taataggtga aggtgaagcc agaaatgaag tcgagcgtac gattttaaat
      181 tacggccttg aaaaaagagt gaaattgcta ggtagtattg ctaatgtcgc cacttattat
      241 tctgcatgtg atatttatgt atcgtcctct aagtgggaag gctttggttt ggttgtagct
      301 gaggctatgt cttgccagcg attggtcgtt gcaactaatg ccggtggggt ggctgaagtt
      361 gttggtgata tgaactatat tgtacctgtt tcagaccctc agttgttggc aaataaaatt
      421 aatgaagtta tggagtttga tcacgaaact aaaatggaag taatgtatag aaatagagag
      481 tttgttttaa aaatgttctc aatagatatg atcgttaatc aatggatgaa attgtattct
      541 tcaatctaat ccatagctta atggaaaaat ataga
//
LOCUS       DAZUDJ010000371          569 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.376, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000371 DAZUDJ010000000
VERSION     DAZUDJ010000371.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.376"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>569
                     /locus_tag="ACHY1N_005565"
     CDS             <1..>569
                     /locus_tag="ACHY1N_005565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4047644.1"
                     /translation="RKRSEEINRQNHQLRVEKILNRSGIQPLHSKCSFANYQVQNDGQ
                     KYALSQAKSIADELMTGCTNFVFSGKTGTGKNHLAAAMGNRLMAKGRSVIIVTVSDVM
                     SVLHDSYDNGKSGEKFLQELCSVDLLVLDEIGVQRETKNEQVVLHQIIDRRTASLCSV
                     GMLTNLNHAAMSTLLGERIMDRMTMNGGR"
BASE COUNT          158 a          126 c          167 g          118 t
ORIGIN      
        1 cgaaaacgca gcgaggagat taaccgccag aatcaccagt tgcgggtgga aaaaatcctg
       61 aatcgttcgg gcatccagcc tctgcacagc aaatgctcgt ttgcgaatta tcaggtgcag
      121 aacgacgggc aaaaatacgc gctgagccag gccaaatcca tagctgacga actgatgacc
      181 gggtgcacga attttgtgtt cagcggtaaa accggcaccg ggaaaaatca ccttgcagcg
      241 gcgatgggta accggctgat ggcgaagggg cgcagcgtga ttatcgtcac cgtgtctgat
      301 gtcatgagcg tgttgcatga cagctacgac aacggcaaat ccggggaaaa atttttacag
      361 gagctttgca gtgttgattt gctggtcctg gatgaaatag gcgttcagcg ggagacgaaa
      421 aacgagcagg tggtattaca ccagataatt gatcgccgga cagcatcact gtgcagtgtc
      481 gggatgttaa caaacctgaa tcatgccgca atgagtacac ttcttggtga gaggattatg
      541 gaccgcatga ccatgaacgg tggtcgatg
//
LOCUS       DAZUDJ010000372          565 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.377, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000372 DAZUDJ010000000
VERSION     DAZUDJ010000372.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..565
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.377"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(2..361)
                     /locus_tag="ACHY1N_005566"
     CDS             complement(2..361)
                     /locus_tag="ACHY1N_005566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tir chaperone family protein"
                     /protein_id="HFS4047645.1"
                     /translation="MNEQFRTDLAHTFGITLEEQTNALSFHDHDGHEWILECAPQSEV
                     LFFYCYLFNNEPSKIDKMLEINSNRDLLGMFFLSLKEDSVLLNIAFPADKVNITEFIN
                     LMENGYLLKNEVISLLS"
BASE COUNT          196 a           84 c           97 g          188 t
ORIGIN      
        1 cttacgacaa taaactaatt acttcattct ttaataaata accgttttcc attaaattga
       61 taaactctgt aatgttaacc ttatctgcag ggaatgcaat attcaaaagt acgctatctt
      121 cttttaatga tagaaaaaac ataccgagta gatctcgatt gctatttatt tctagcattt
      181 tatcaatttt tgaaggttca ttattgaata aataacaata aaaaaacagg acctcagatt
      241 gaggcgcaca ctccagtatc cattcatgac catcgtgatc atggaaagag agggcgttag
      301 tttgttcttc aagagttatt ccgaacgtat gtgcaagatc tgtgcgaaat tgttcattca
      361 tattgtagtc ctgtcattct ttcaatgagg gtatgcttaa acgtaattaa ctcgtgagtt
      421 ctggcacaaa taataagacg aaaatataag atgcgagtaa tagtgttgca tatttatgat
      481 agcatgtgat aaatgtagtg caactacttg tggatagtgc cggaggaaaa tttaaatata
      541 aaacaattat tgtttttaat gaaaa
//
LOCUS       DAZUDJ010000373          564 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.378, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000373 DAZUDJ010000000
VERSION     DAZUDJ010000373.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..564
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.378"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(149..340)
                     /locus_tag="ACHY1N_005567"
     CDS             complement(149..340)
                     /locus_tag="ACHY1N_005567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1482 family protein"
                     /protein_id="HFS4047646.1"
                     /translation="MNTAFALVLTVFLVSGEPVDIAVSVHRTMQECVTAATEQKIPGN
                     CYPVDKVIHQDNNEIPAGL"
     gene            complement(337..525)
                     /gene="dicB"
                     /locus_tag="ACHY1N_005568"
     CDS             complement(337..525)
                     /gene="dicB"
                     /locus_tag="ACHY1N_005568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibition protein DicB"
                     /protein_id="HFS4047647.1"
                     /translation="METLLPNVNTSEGCFEIGVTISNPVFTEDAINKRKHERELLNKI
                     CILSMLARLRPIQKGCWQ"
BASE COUNT          153 a          118 c          110 g          183 t
ORIGIN      
        1 tcttccttta ttgcctgttc gtccggaatg gcggcgcaaa taaagacttt actcattttg
       61 ttttacctca ttacagattt aagggtgaac aaatccctgc cattgctggc atataagaat
      121 gaaatcggat gtttattacg gaactgtttt aaagacctgc cgggatttcg ttattatcct
      181 ggtgaataac tttatcgacc gggtaacagt taccgggaat tttctgttcg gttgctgcag
      241 ttacacactc ctgcattgtc ctgtgaacac tgactgcaat atcaactggc tctccggaaa
      301 caagaaaaac tgtcagaaca agtgcaaatg ctgtattcat tgccagcatc ctttttgtat
      361 cggacgtaaa cgggccagca ttgaaagaat gcatatttta tttaatagct cccgttcgtg
      421 ttttctcttg ttaatggcat cttcagtaaa tacagggtta ctgatagtga caccaatttc
      481 aaaacaacct tcagacgtat taacgtttgg taataacgtt tccattatcg cgtcctcaac
      541 aatgaatttt gtgatgcagt gcct
//
LOCUS       DAZUDJ010000374          559 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.379, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000374 DAZUDJ010000000
VERSION     DAZUDJ010000374.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..559
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.379"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>559)
                     /locus_tag="ACHY1N_005569"
     CDS             complement(<1..>559)
                     /locus_tag="ACHY1N_005569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4047648.1"
                     /translation="GSIKELLDYQFSTNEIAAVVAERDVEWWQNRASVLTTPQLASGY
                     FNAGFLLINIDEWNLNNISSKAIEMLRDPDWVSKITHLDQDVLNVLLNGKVKFISEKY
                     NTRYSINYELKDKVDNPVNDDTVFIHYVGPTKPWHEWADYPVSRSFLIAKAASPWSKE
                     DLLKPVNSNQYRYCAKHKFKQKHYMA"
BASE COUNT          170 a          112 c           87 g          190 t
ORIGIN      
        1 tgccatataa tgcttttgtt taaatttatg ttttgcacaa taccgatact gattgctatt
       61 tacaggttta agtaaatctt ctttactcca cggagaagct gctttggcga tcaaaaaact
      121 acgtgacacc ggatagtcag cccactcatg ccagggtttt gtaggtccca catagtgtat
      181 aaacacggtg tcatcattga ctggattatc aactttgtct tttaattcat agttaatact
      241 atatcgggta ttatatttct ccgaaataaa cttcacttta ccattcaata atacattcag
      301 tacatcttga tcaaggtggg tgattttact tacccaatct gggtcacgca acatttcaat
      361 agcttttgac gaaatgttat ttagattcca ctcatcaata tttatcagta aaaaaccagc
      421 attgaaatat ccagaagcta actgtggtgt agttaatacc gaggctcgat tttgccacca
      481 ttcaacatct ctttcagcta caactgcggc aatttcatta gtagaaaatt gataatctaa
      541 gagttcttta atactaccc
//
LOCUS       DAZUDJ010000375          549 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.380, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000375 DAZUDJ010000000
VERSION     DAZUDJ010000375.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.380"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>549
                     /locus_tag="ACHY1N_005570"
     CDS             <1..>549
                     /locus_tag="ACHY1N_005570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HFS4047649.1"
                     /translation="YRYDSDGRVTEQLNPAGLSYTYQYEKDHITITDSLDRREVLHTQ
                     GEAGLKRVVKKEHADGSVTQSQFDAVGRLKAQTDAAGRTTEYSPDVVTGLITRITTPD
                     GRASAFYYNHHSQLTSATGPDGLEMRRKYDEYGRLIQETAPDGDITRYRYDNPHSDLP
                     CATDDATGSRKTMTWSRYGQLL"
BASE COUNT          141 a          160 c          166 g           82 t
ORIGIN      
        1 gttaccgtta cgacagcgac gggcgggtga cagaacagct taacccggca ggcttaagct
       61 acacgtatca gtatgagaaa gaccacatca ccatcaccga cagcctggac cgccgtgaag
      121 tgctgcacac gcagggcgaa gccgggctga agcgggtggt gaaaaaggaa cacgcggacg
      181 gcagcgtcac gcagagtcag tttgatgcgg tgggcaggct taaggcacag acggatgccg
      241 caggccggac aacagagtac agcccggatg tggtgacggg cctcatcacg cgcatcacca
      301 cgccggatgg cagggcatcg gcgttttact ataaccacca cagccagtta acgtcagcca
      361 ccgggccaga cgggctggaa atgcgccgca aatatgatga gtacggacgt ctgattcagg
      421 aaaccgcccc tgacggcgat atcacccgct accgttatga taatccacac agtgacctcc
      481 cctgcgcaac ggacgatgcc accggcagcc ggaaaaccat gacgtggagc cgttacggtc
      541 agttgctga
//
LOCUS       DAZUDJ010000376          540 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.381, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000376 DAZUDJ010000000
VERSION     DAZUDJ010000376.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.381"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..182
                     /locus_tag="ACHY1N_005571"
     CDS             <1..182
                     /locus_tag="ACHY1N_005571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310019.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047650.1"
                     /translation="GWFPDTDGALITGLTFLAPKDATRVQGFFQHLQVRFGDGPWQDV
                     KGLDEVGSDTGRTGE"
     gene            184..453
                     /locus_tag="ACHY1N_005572"
     CDS             184..453
                     /locus_tag="ACHY1N_005572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047651.1"
                     /translation="MNILKKIMQRLCGCGKHDDREDGELLTAQLRLGPADILESDENG
                     IIPEQDRVITQVVILDADKKQIQCVVRPLQILRADGRWENIGGMK"
BASE COUNT          145 a          103 c          169 g          123 t
ORIGIN      
        1 atggctggtt cccggataca gatggcgcac tcatcaccgg actgaccttt cttgccccca
       61 aagatgccac acgggttcag ggtttttttc agcatttgca ggtcaggttt ggtgacgggc
      121 cgtggcagga tgttaagggg ctggatgaag tgggcagtga tacaggcaga acaggagaat
      181 gacatgaaca tattaaaaaa aattatgcag cgtctgtgcg gttgcggaaa gcatgatgac
      241 cgtgaagacg gggagttact tacagcacaa ctgcgactgg ggccggcaga catcctggag
      301 tccgatgaga atggtattat cccggagcag gacagggtaa tcacgcaggt ggtgatactg
      361 gatgcggata aaaagcagat acagtgtgtg gtaagaccgc tgcaaatcct gcgtgctgac
      421 gggaggtggg aaaatattgg cggaatgaaa tagccgacag cttcacaaaa accggagtcc
      481 ggctccggtt tttgttgtca tgtcatggtg atgtttgtta ataaagactt gagggaatat
//
LOCUS       DAZUDJ010000377          537 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.382, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000377 DAZUDJ010000000
VERSION     DAZUDJ010000377.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..537
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.382"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>537
                     /locus_tag="ACHY1N_005573"
     CDS             <1..>537
                     /locus_tag="ACHY1N_005573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HFS4047652.1"
                     /translation="YRYDSDGRVTEQLNPAGLSYTYQYEKDRITITDSLNRREVLHTQ
                     GEAGLKRVVKKEHADGSVTQSQFDAVGRLKAQTDAAGRTTEYSPDVVTGLTTPDGRAS
                     AFYYNHHNQLTSATGPDGLELRREYDESGRLIQETAPDGDITRYRYDNPHSDLPCATE
                     DATGSRKTMTWSRYGQLL"
BASE COUNT          140 a          152 c          162 g           83 t
ORIGIN      
        1 gttaccgtta cgacagcgac gggcgggtga cagaacagct aaacccggca ggcttaagtt
       61 acacgtatca gtatgaaaaa gaccgcatca ccatcaccga cagcctgaac cgccgtgaag
      121 tgctgcacac gcagggcgaa gccgggctga agcgggtggt gaaaaaggaa cacgcggacg
      181 gcagcgtcac gcagagtcag tttgacgcgg tgggcaggct taaggcacag acggatgccg
      241 caggccggac aacagaatac agcccggatg tggtgacggg cctcaccacg ccggatggca
      301 gggcatcggc gttttactat aaccaccaca accagttaac gtcagccacc gggcctgacg
      361 ggctggaatt gcgccgggaa tatgatgaat ccggccgtct gattcaggaa actgcccctg
      421 acggcgatat cacccgctac cgttatgata atccacacag tgacttaccc tgcgcaacgg
      481 aagatgccac cggcagccgg aaaaccatga cgtggagccg ttacggtcag ttgctga
//
LOCUS       DAZUDJ010000378          536 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.383, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000378 DAZUDJ010000000
VERSION     DAZUDJ010000378.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.383"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(44..409)
                     /locus_tag="ACHY1N_005574"
     CDS             complement(44..409)
                     /locus_tag="ACHY1N_005574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFS4047653.1"
                     /translation="MAVLRTLPGRIKTLNTRRVNVLKGEQRRVSGSARVSLKRRIWLR
                     DAGQCCLCGRVVDLCDSELEHRIALQFGGGNEETNLWTLCTECHRQKSAREAASGMPD
                     PTLPEVSGGSGRADDIIGL"
     gene            451..>536
                     /locus_tag="ACHY1N_005575"
     CDS             451..>536
                     /locus_tag="ACHY1N_005575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3950 domain-containing protein"
                     /protein_id="HFS4047654.1"
                     /translation="MSSKNRPRRTTTRNIRFPNQMIEQINIAL"
BASE COUNT          137 a          172 c          117 g          110 t
ORIGIN      
        1 aagcgatctt tttttacgcc ggatgatacc cccccgggtc gggttacagt ccgatgatgt
       61 cgtccgctct gccactacct ccggacacct ccggcagcgt cgggtctggc ataccactcg
      121 ccgcttcacg agcagacttt tgtcgatggc attcggtaca gagcgtccag agattcgtct
      181 cctcattacc accaccgaac tgaagtgcaa tgcggtgctc aagttcactg tcacaaaggt
      241 caaccacacg cccacagaga cagcactgtc cggcatccct cagccagata cgacgcttga
      301 gggaaacccg ggcactacca ctgacccgac gctgttcacc cttcaggaca ttcacccgcc
      361 gggtgttcag agttttgatt ctgcccggta acgtacgaag cacagccatg taaaatcctc
      421 tccatatagc ttgtcaccag aggaaagaaa atgtcatcga aaaaccggcc ccgcagaaca
      481 acaacccgca acatccgatt tccaaaccag atgattgaac aaattaacat cgctct
//
LOCUS       DAZUDJ010000379          531 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.384, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000379 DAZUDJ010000000
VERSION     DAZUDJ010000379.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.384"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..200)
                     /locus_tag="ACHY1N_005576"
     CDS             complement(<1..200)
                     /locus_tag="ACHY1N_005576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047655.1"
                     /translation="MTENVKSELLLLMADNNEATSSILADPYGKISHKTLDIITTTLT
                     PLMLQRLKHNINAWVNEELSPP"
     gene            360..>531
                     /locus_tag="ACHY1N_005577"
     CDS             360..>531
                     /locus_tag="ACHY1N_005577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HFS4047656.1"
                     /translation="MNEKIKYGLSAAVLALIGAGASAPEILDQFLDEKEGNHTTAYRD
                     GAGIWTICRGAIL"
BASE COUNT          134 a          104 c          125 g          168 t
ORIGIN      
        1 cagggaggac ttaattcttc attaacccat gcgttgatat tatgtttcag ccgttgaagc
       61 atcagcggtg ttaatgttgt ggtaataata tccagcgttt tatgtgagat cttaccgtaa
      121 gggtctgcaa gaatgctgct tgttgcttcg ttattatctg ccatcagaag aagtaactct
      181 gatttaacgt tttctgtcat tagttgtaaa aatcttctgc gcaaactttc tttactgttc
      241 atttatatgg cttcatttgt tgtaatctgc tgcgtctcaa gggatatgtt tatgagagcg
      301 accatgagtg ttggattata tacctaacat atcaagggat tagaaatcga taaatcccca
      361 tgaacgaaaa aataaaatac ggcctgtcgg ctgccgttct ggcgctgatt ggtgcaggtg
      421 cttctgcgcc tgaaatcctc gaccagtttc tggatgaaaa ggaaggtaac cacaccacgg
      481 cataccgtga tggtgcgggg atctggacca tctgccgtgg tgccattctg g
//
LOCUS       DAZUDJ010000380          529 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.385, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000380 DAZUDJ010000000
VERSION     DAZUDJ010000380.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.385"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            6..>529
                     /locus_tag="ACHY1N_005578"
     CDS             6..>529
                     /locus_tag="ACHY1N_005578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFS4047657.1"
                     /translation="MKEMISVDHEISMSSLDFLNNIINPARAEAGEVPHEPRKFLAKI
                     EDELELDGTGKKFRLNNNQTRTAYYDLDFDQMMLVGMRESKAVRRSVLARLKAMHGIQ
                     IPRTLPEALRFAAKLAEQKAVLENQLAIAAPKAEFVDNYVEASGLMGFREVAKLLGIK
                     ETDFRLFLLENGIM"
BASE COUNT          157 a          101 c          137 g          134 t
ORIGIN      
        1 caaccatgaa agagatgatt tctgtcgatc atgaaatatc catgagtagt ctggattttc
       61 tgaataacat tattaatcca gcccgggcag aagccggaga agtccctcat gaaccgcgta
      121 agtttcttgc aaaaattgag gatgagctag agcttgatgg aaccggaaaa aaattccggt
      181 taaacaataa ccagacaaga acggcatact atgatctgga ttttgaccag atgatgctcg
      241 ttggcatgag ggagtcaaag gccgttcgtc gttctgtgct ggcaagactc aaagcgatgc
      301 atggtattca gatcccccgg actttacctg aggcgttgcg atttgcggca aaactggctg
      361 aacagaaagc agtgctggaa aatcaactgg caatagcagc gccgaaggct gaatttgttg
      421 ataactatgt tgaagcatct ggtctgatgg gattccggga agttgctaag ttactcggta
      481 tcaaagaaac cgatttccgg ctgtttttgt tggagaacgg aataatgta
//
LOCUS       DAZUDJ010000381          519 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.386, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000381 DAZUDJ010000000
VERSION     DAZUDJ010000381.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.386"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>519
                     /gene="rfaY"
                     /locus_tag="ACHY1N_005579"
     CDS             <1..>519
                     /gene="rfaY"
                     /locus_tag="ACHY1N_005579"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II) kinase RfaY"
                     /protein_id="HFS4047658.1"
                     /translation="DFLTCRVKTLKVFRSIDDTKVILIDTARGPLVLKVYAPKHKMTE
                     RFLKSCIKKDYYENLIYQTDRVRGEGIQSINDYFLLAERKTLNFAHYYIMLIEYIEGV
                     GLNEYLEISEDLKDQLSESIKELHQHGMVSGDPHKGNFIVSEKGLRLIDLSGKKTTAV
                     LKAKDRIDLERH"
BASE COUNT          179 a           77 c           95 g          168 t
ORIGIN      
        1 tgacttttta acttgcaggg ttaaaacatt aaaagttttt cgttcgattg atgatactaa
       61 agtcattctt attgacactg ctcgtggacc tcttgtactt aaagtttatg cgccaaagca
      121 taaaatgacc gaacgtttct taaaatcttg cataaaaaaa gattattatg aaaatttaat
      181 ttatcaaacc gatcgggtac gtggtgaagg catccaatca attaatgact attttttgct
      241 agctgaacgt aaaacattaa atttcgctca ttattatatt atgctcattg agtatattga
      301 aggtgtcggg ttaaatgagt atttggaaat ttctgaagat ctgaaggatc aattatcaga
      361 atcgataaaa gagttgcatc agcatggaat ggtgtctggc gatcctcata aaggaaattt
      421 tatagtatcc gaaaaaggtt taagactaat tgacctttca ggtaaaaaaa caaccgctgt
      481 tttaaaagca aaagatcgca ttgatcttga acggcacta
//
LOCUS       DAZUDJ010000382          517 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.387, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000382 DAZUDJ010000000
VERSION     DAZUDJ010000382.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.387"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..110)
                     /locus_tag="ACHY1N_005580"
     CDS             complement(<1..110)
                     /locus_tag="ACHY1N_005580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HFS4047659.1"
                     /translation="MNLVMSDITRNKLGCYMAQQASLNNIPVSALVSRFTV"
     gene            complement(134..>517)
                     /locus_tag="ACHY1N_005581"
     CDS             complement(134..>517)
                     /locus_tag="ACHY1N_005581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HFS4047660.1"
                     /translation="MTFNSVQGEAPLISEAIESEIIEMAEQRQEEGTQWFNRVMGIIG
                     RGRKADDASFSRIQEAVEGVATSQADIIDRFNVLETRHQQDRQKITSLTTELTALKEK
                     LRTQDGDPQNRFTATGAASDQLADF"
BASE COUNT          105 a          141 c          134 g          137 t
ORIGIN      
        1 acggtaaatc gcgataccag cgcagaaacc gggatattgt taagcgacgc ctgctgcgcc
       61 atatagcaac ccagcttgtt gcgggtaata tctgacatca ccagattcat aaaaaatttg
      121 ctcctttgtc ttatcagaag tcagccagct ggtcggaggc tgcgcccgtt gcggtgaacc
      181 ggttctgcgg atcgccgtcc tgcgtgcgca gtttttcctt cagtgctgtc agctctgtgg
      241 tcagtgacgt aattttctgg cggtcctgct gatggcgggt ttccagcaca ttaaaacggt
      301 cgataatgtc agcctgtgac gttgcgacgc cttccaccgc ttcctgaata cgggaaaaac
      361 tggcgtcatc cgctttgcgg ccacggccaa taatccccat tacgcggtta aaccactggg
      421 tgccttcttc ctggcgttgt tctgccattt cgatgatttc agactcgatg gcttcggaga
      481 taagcggcgc ttcaccctgg acactgttga acgtcat
//
LOCUS       DAZUDJ010000383          516 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.388, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000383 DAZUDJ010000000
VERSION     DAZUDJ010000383.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.388"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>516
                     /locus_tag="ACHY1N_005582"
     rRNA            <1..>516
                     /locus_tag="ACHY1N_005582"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          149 a          115 c          150 g          102 t
ORIGIN      
        1 tttaagcgtg taggctggtt ttccaggcaa atccggaaaa tcaaggctga ggcgtgatga
       61 cgaggcacta cggtgctgaa gcaacaaatg ccctgcttcc aggaaaagcc tctaagcatc
      121 aggtaacatc aaatcgtacc ccaaaccgac acaggtggtc aggtagagaa taccaaggcg
      181 cttgagagaa ctcgggtgaa ggaactaggc aaaatggtgc cgtaacttcg ggagaaggca
      241 cgctgatatg taggtgaagc gacttgctcg tggagctgaa atcagtcgaa gataccagct
      301 ggctgcaact gtttattaaa aacacagcac tgtgcaaaca cgaaagtgga cgtatacggt
      361 gtgacgcctg cccggtgccg gaaggttaat tgatggggtc agcgcaagcg aagctcttga
      421 tcgaagcccc ggtaaacggc ggccgtaact ataacggtcc taaggtagcg aaattccttg
      481 tcgggtaagt tccgacctgc acgaatggcg taatga
//
LOCUS       DAZUDJ010000384          510 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.389, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000384 DAZUDJ010000000
VERSION     DAZUDJ010000384.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.389"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>510)
                     /locus_tag="ACHY1N_005583"
     CDS             complement(<1..>510)
                     /locus_tag="ACHY1N_005583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFS4047661.1"
                     /translation="RELEAGKAATAQPVKQAGNGNVAAVASAPVIRVEQKLDKGIGFA
                     RFAKSLAAAKGVRSEALEVARRQYPDDSRLHHVLKSAVGAGTTTDPQWAGSLSEYQEY
                     AQDFIDYLRPQTIIGRFGQGGIPALRQVPFNIRVHAQVSGGAAGWVGEGKARPLTKFD
                     FESITFSHA"
BASE COUNT          105 a          170 c          136 g           99 t
ORIGIN      
        1 ttcgcatgac tgaaggtgat ggattcaaaa tcaaacttcg tcaggggtct ggccttaccc
       61 tcacccaccc agccggcagc accgccggac acctgggcgt gcacacggat attgaacggc
      121 acctgacgaa gtgcagggat cccgccctga ccaaatcgcc cgataatggt ctgcggacgc
      181 aggtaatcaa taaagtcctg tgcgtattcc tgatattcag acaggctgcc tgcccactgc
      241 ggatccgtgg tggtccccgc gcccactgcc gatttcagga catgatgcag acgactgtca
      301 tccggatact gacgacgggc cacttccagg gcttcagatc ggacgccttt agccgcagcc
      361 agcgatttgg caaagcgggc gaagccaatc cccttatcca gtttctgctc cacacggatc
      421 accggcgcag aagccaccgc ggccacattc ccgttaccgg cctgtttcac cggctgcgcc
      481 gtggcggcct taccggcttc cagttcacgc
//
LOCUS       DAZUDJ010000385          503 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.390, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000385 DAZUDJ010000000
VERSION     DAZUDJ010000385.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.390"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..137
                     /locus_tag="ACHY1N_005584"
                     /pseudo
     CDS             1..137
                     /locus_tag="ACHY1N_005584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_303550.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(332..445)
                     /locus_tag="ACHY1N_005585"
     CDS             complement(332..445)
                     /locus_tag="ACHY1N_005585"
                     /inference="COORDINATES: protein motif:HMM:NF024464.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3927 family protein"
                     /protein_id="HFS4047662.1"
                     /translation="MVDFTSRIMSVLADGVLVCGIMVLLWPVIKRNSLHNA"
BASE COUNT          157 a          130 c          111 g          105 t
ORIGIN      
        1 taatgtttaa tcgacatcga atttctcccg tgtagaggaa cagagttaaa aagccggaag
       61 cggaatcaaa tcacaggatg accatctgcc agtggctggt cgtaaaaaaa aggccgcgcc
      121 atgcgcagcc gaaaataaag ggataacgat gatagtttga gaaaaacaga aataacactt
      181 ttgtggcaaa gcatggtgcc gggtgcctcc cggtgaattc agtatcagca cctgaatccg
      241 cgattacccc atattccttc ttgctgattg ccccaccgca cagggggatt caccatgcag
      301 aagtgttttt aataaacagc aaacaaaaaa atcaagcatt atgcaggctg tttcttttta
      361 tcaccggcca cagcaatacc ataatgccgc agaccagcac cccatccgcc agcaccgaca
      421 tgattctgct ggtgaaatcc accatcacca ccagaaacag caggagtgca gccacagtca
      481 ggcgcagttt taccgtcaca ggt
//
LOCUS       DAZUDJ010000386          493 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.391, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000386 DAZUDJ010000000
VERSION     DAZUDJ010000386.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.391"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            63..>493
                     /locus_tag="ACHY1N_005586"
     CDS             63..>493
                     /locus_tag="ACHY1N_005586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019069 - viral capsid assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HFS4047663.1"
                     /translation="MANEKKTSRKKFRVAVSGSTVDGREISPVHLREAAENFNPDVYA
                     ARVNVEHYLSPCPSSEFSAMGDVTALSTEDITEGPLAGRTALYAEIEPTERMKQLVAD
                     GKKIYSSIELHPQFSVNGRAYLVGLAMTDTPASLGTERLKFT"
BASE COUNT          121 a          138 c          133 g          101 t
ORIGIN      
        1 tttgtatcag cctgttacgc tttgccatca tgactgaaga accagtcaga ggggcaaaaa
       61 ctatggctaa tgaaaaaaag acatcccgca aaaagtttcg cgtggctgtc tccggatcaa
      121 ctgttgatgg ccgtgaaatc agtccggtgc atctgcgtga agccgccgag aacttcaacc
      181 cggatgttta cgctgcccgc gtgaacgttg agcactatct ctcgccatgc ccgtcaagcg
      241 aattttccgc aatgggcgat gtcaccgcac tgagtacgga agacattacg gaaggtccgc
      301 tggccggacg tactgcgctg tatgcagaaa tcgaaccgac cgagcgcatg aagcagcttg
      361 tcgcggacgg caagaaaatc tattccagta tcgaactgca cccgcagttc tccgttaacg
      421 ggcgcgccta tctggtcggg ctggcgatga ccgacacccc ggcaagcctg ggcactgagc
      481 gcctgaaatt cac
//
LOCUS       DAZUDJ010000387          488 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.392, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000387 DAZUDJ010000000
VERSION     DAZUDJ010000387.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.392"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..466
                     /locus_tag="ACHY1N_005587"
     CDS             <1..466
                     /locus_tag="ACHY1N_005587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS600 family transposase"
                     /protein_id="HFS4047664.1"
                     /translation="YVATQEGWLYLAGIKDVYTCEIVGYAMGERMTKELTGKALFMAL
                     RSQRPPAGLIHHSDRGSQYCAYDYRVIQEQFGLKTSMSRKGNCYDNAPMESFWGTLKN
                     ESLSHYRFNNRDEAISVIREYIEIFYNRQRRHSRLGNISPAAFREKYHQMAA"
BASE COUNT          138 a          112 c          126 g          112 t
ORIGIN      
        1 gtatgttgcc acacaggagg gatggttgta cctcgctggc atcaaagatg tttatacgtg
       61 cgaaattgtc ggctacgcca tgggagagcg catgacaaaa gagctgacag gtaaagctct
      121 gtttatggcg ctcaggagcc agcgcccacc tgccgggcta atccaccact ctgatcgagg
      181 ttcacagtac tgcgcatacg attaccgggt catacaggag cagtttggtc tgaaaacatc
      241 aatgtcgcgt aaaggtaact gttacgacaa cgctccgatg gaaagcttct ggggaacgct
      301 gaaaaatgag agcctgagcc actatcgttt taataaccgg gatgaagcca tctcagtaat
      361 acgggaatac attgagattt tctacaatcg tcagcgtcgt cactctcgtc tggggaatat
      421 ctccccggca gccttcaggg aaaaatatca tcagatggct gcttaaaaaa agaacaaatg
      481 gtagtgtc
//
LOCUS       DAZUDJ010000388          486 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.393, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000388 DAZUDJ010000000
VERSION     DAZUDJ010000388.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.393"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
BASE COUNT          190 a          108 c           55 g          133 t
ORIGIN      
        1 gtgatcatgt agcataagta acctccgttt atctacagac tgccatcctg aatttaccgt
       61 ccttaataag acaacaataa aaaactaatt atataaaaac aataaaaata atatacaaaa
      121 aaactaaaca acaaagaaaa gcaaatcata tctggcattt taattgaaag agcaattacc
      181 gaacaaaaga cgctgactat atactcaaaa ccaaacaaca attctgccaa tcaggtatca
      241 tggcaacaca cggaattacc atgtttttgc cttctctgcc catacaatac gggcatatac
      301 ttcatactct attgtaatat ttctatccat gcgccccact ccatttacct gtaaataata
      361 ttcaaaatat ttatcacaga aatcgttttt ggccatgaac tgagcacact ataaagtccg
      421 gaactgactc tttgttaaat taccttaacg ttaccagtaa caccttcata acaaaacatc
      481 acggta
//
LOCUS       DAZUDJ010000389          485 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.394, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000389 DAZUDJ010000000
VERSION     DAZUDJ010000389.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.394"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..485)
                     /locus_tag="ACHY1N_005588"
     CDS             complement(<1..485)
                     /locus_tag="ACHY1N_005588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001485704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HFS4047665.1"
                     /translation="MRVFHGGRVLVESEPKSMRNLPSGVVPAVRQPLAEDKSLLPFFS
                     NERVIRAAGGAGALSDWLLRHVKSCQWPHGDYHHSETVIHRYGTGAMVLCWHCDNQLR
                     DQTSESLEQLAQQNLSAWMIDVIRHAMNGIQERELSLAELSWWAVCNQVVDALPEAVS
                     RR"
BASE COUNT          119 a          140 c          120 g          106 t
ORIGIN      
        1 cgacgcgata ctgcctcagg taatgcgtcc accacctgat tgcagactgc ccaccaggat
       61 aattcagcca gcgataattc ccgttcctgt atgccattca ttgcgtggcg gatgacgtca
      121 atcatccatg ctgacaggtt ttgttgagca agttgctcaa gtgattcgga tgtctggtcg
      181 cgcagctggt tgtcgcagtg ccagcacaac accatcgcgc cggtaccgta acgatgtatg
      241 acagtttcgc tgtgatgata atcaccatga ggccactggc aggatttaac gtgacgtaat
      301 aaccagtcag acagtgcacc agcgccacca gcagcacgaa tcacacgctc attgctgaaa
      361 aatggcagta atgatttatc ttccgccagc ggctggcgaa cggcaggaac gaccccggac
      421 ggcagattac gcatgctttt cggttcagac tccaccagca ccctgccgcc atgaaatacc
      481 cgcat
//
LOCUS       DAZUDJ010000390          482 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.395, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000390 DAZUDJ010000000
VERSION     DAZUDJ010000390.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.395"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>482
                     /locus_tag="ACHY1N_005589"
     rRNA            <1..>482
                     /locus_tag="ACHY1N_005589"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          107 a          107 c          157 g          111 t
ORIGIN      
        1 gaagtgtgga cgccagtctg catggagccg gccttgaaat accacccttt aatgtttgat
       61 gttctaacgt tgacccgtga tccgggttgc ggacagtgtc tggtgggtag tttgactggg
      121 gcggtctcct cctaaagagt aacggaggag cacgaaggtt ggctaatcct ggtcggacat
      181 caggaggtta gtgcaatggc ataagccagc ttgactgcga gcgtgacggc gcgagcaggt
      241 gcgaaagcag gtcatagtga tccggtggtt ctgaatggaa gggccatcgc tcaacggata
      301 aaaggtactc cggggataac aggctgatac cgcccaagag ttcatatcga cggcggtgtt
      361 tggcacctcg atgtcggctc atcacatcct ggggctgaag taggtcccaa gggtatggct
      421 gttcgccatt taaagtggta cgcgagctgg gtttagaacg tcgtgagaca gttcggtccc
      481 ta
//
LOCUS       DAZUDJ010000391          475 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.396, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000391 DAZUDJ010000000
VERSION     DAZUDJ010000391.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.396"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..174)
                     /locus_tag="ACHY1N_005590"
     CDS             complement(<1..174)
                     /locus_tag="ACHY1N_005590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ESPR domain-containing protein"
                     /protein_id="HFS4047666.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAA
                     VTSVPALAADTVVQ"
BASE COUNT          123 a          120 c          120 g          112 t
ORIGIN      
        1 ctgtacaacc gtgtcagcag ccagtgccgg gactgatgtg acagcagcaa gagacagcgc
       61 aaccgccaca ccggcgcgtt ttccccgtga gcgggccagt tcggaggcca ccaccagggt
      121 gcccgtaatg tgattccata ccagcctgta gctggtgttc agatgtcgtt tcatcagctt
      181 ttccttacag agggtgaata aaaaagccgg tacccacaga tgtgggtacc ggcaggtaca
      241 aaacagcatg gtcagataaa gtggtttttc ccggacataa atgtttcccc tctctcatcc
      301 gccagagaag catcagtccg ttgtgtgcaa ttccgttctg catgatgaag agattcagct
      361 gccttttcgc agaccattaa ccactataaa cgatcgatag taacgatcga tacctgtttt
      421 atcgatcgtt ttattctatt aacagcaggg aagtcacgca agagaaagag gtggg
//
LOCUS       DAZUDJ010000392          472 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.397, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000392 DAZUDJ010000000
VERSION     DAZUDJ010000392.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.397"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>472
                     /locus_tag="ACHY1N_005591"
     CDS             <1..>472
                     /locus_tag="ACHY1N_005591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308587.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HFS4047667.1"
                     /translation="GWRGGWSLYAYPLNPVNGIDPLGLSPADVALIRRKDQLNHQRAW
                     DILSDTYEDMKRLNLGGTDQFFHCMAFCRVSKLNDAGVSRSAKGLGYEKEIRDYGLNL
                     FGMYGRKVKLSHSEMIEDNKKDLAVNDHGLTCPSTTDCSDRCSDYINPEHKKTIK"
BASE COUNT          160 a           65 c          120 g          127 t
ORIGIN      
        1 gggctggagg gggggatgga gtctgtatgc gtacccgctg aatccggtga atggtattga
       61 tccattaggg ttaagtcccg cagatgtagc gctaataaga agaaaagatc aactaaacca
      121 tcaaagagca tgggatatat tatctgatac ttatgaagat atgaagagat taaatttagg
      181 tgggactgat caatttttcc attgtatggc attttgtcga gtgtctaaat taaatgacgc
      241 tggtgttagc cgatcggcga aagggctggg ttatgaaaaa gagattagag attacgggtt
      301 aaatctgttc ggtatgtacg gcagaaaagt aaagctatcc cattctgaaa tgattgaaga
      361 taataaaaaa gacttggctg taaatgacca tgggttgaca tgtccatcaa caacagattg
      421 ctcagataga tgtagtgatt atattaatcc agagcataaa aaaacgataa ag
//
LOCUS       DAZUDJ010000393          464 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.398, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000393 DAZUDJ010000000
VERSION     DAZUDJ010000393.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.398"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>464
                     /locus_tag="ACHY1N_005592"
     CDS             <1..>464
                     /locus_tag="ACHY1N_005592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308587.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
                     /protein_id="HFS4047668.1"
                     /translation="ITLWHYDASDRITHRTVNGDPAEQWQYDEHGWLTTLSHTSEGHR
                     VSVHYGYDDKGRLTGERQTVENPETGELLWQHETKHAYNEQGLANRVTPDSLPPVEWL
                     TYGSGYLAGMKLGGTPLVEYTRDRLHRETVRSFGSRAGSNAAYELTSTYTPAG"
BASE COUNT          105 a          142 c          160 g           57 t
ORIGIN      
        1 atcaccctct ggcactacga tgcgtcggac cgcatcacgc accggacggt gaacggcgac
       61 ccggcagagc agtggcagta tgatgagcac gggtggttaa ccaccctcag ccataccagt
      121 gaaggccacc gcgtgtcggt ccactacggc tacgacgata agggccgcct gacgggcgaa
      181 cggcagacgg tggagaaccc ggagacgggg gaactgctgt ggcagcatga gacgaaacac
      241 gcctacaacg aacaggggct ggcaaaccgc gtcacgccgg acagcctgcc gccggtggag
      301 tggctgacct acggcagcgg ttacctggcg ggcatgaagc tgggcgggac gccgctggtc
      361 gagtatacgc gggacaggct gcaccgtgag acggtgcgca gcttcggcag cagggcaggc
      421 agtaatgccg catacgaact gaccagcaca tacacccccg cagg
//
LOCUS       DAZUDJ010000394          462 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.399, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000394 DAZUDJ010000000
VERSION     DAZUDJ010000394.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.399"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..334
                     /locus_tag="ACHY1N_005593"
     CDS             <1..334
                     /locus_tag="ACHY1N_005593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IrmA family protein"
                     /protein_id="HFS4047669.1"
                     /translation="PGNICAYQFRLDNGGNDEGFGPLTITLQLKDKYGQTLVTRKMET
                     EAFGDSNATRTTDAFLETECVENVATTEIIKATEESNGHRVSLPLSVFNPQDYHPLLI
                     TVSGKNVN"
BASE COUNT          133 a          111 c          109 g          109 t
ORIGIN      
        1 cccgggaaat atttgtgctt accagttccg gctggataat ggcggaaacg atgaaggatt
       61 tggccccctc accatcactc tgcaactcaa agacaaatat ggtcagacgc tggtgaccag
      121 aaaaatggaa acggaagctt ttggtgacag taatgccacg cgaaccacag acgcatttct
      181 ggaaacggag tgcgtggaaa atgtcgccac aaccgaaatc attaaagcaa ctgaagaaag
      241 taacggccat cgtgtcagtc tgccgttatc ggttttcaat ccccaggact accatccact
      301 gctgattacc gtttccggaa aaaacgttaa ctgatccctg aagtcagttt catgcttcag
      361 cctctgtcac aacgcgtggc agaggctttt tatttatcag gagaaaacag atatgccggg
      421 ttacacagag tatgtcctgg ctgaaggatc tttctcatac gg
//
LOCUS       DAZUDJ010000395          462 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.400, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000395 DAZUDJ010000000
VERSION     DAZUDJ010000395.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.400"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>462
                     /locus_tag="ACHY1N_005594"
     CDS             <1..>462
                     /locus_tag="ACHY1N_005594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4047670.1"
                     /translation="DAALLPALRLGNARADDLVRNNGIAANAVALHKDHIVGHMFLIS
                     YRPNWRWLGMRETAAKSFVDEVEAAWSEYAEGMSGEIDVEGKRTFTEFIREGVGVHAF
                     NGEIFVQPVWDTETTQLFRTRFKAVSPKRVDTPGHGMGNRFLRAGVEVDRYG"
BASE COUNT           98 a          104 c          163 g           97 t
ORIGIN      
        1 cgatgcggcc ctgctgcccg cgttgcgtct ggggaatgcc cgggcagatg atctggtgcg
       61 caataacgga atagcggcta atgcggtggc cctgcataag gatcacattg tcgggcatat
      121 gtttctgatc agctaccgtc cgaactggcg ctggctgggg atgcgggaga ccgcagcaaa
      181 aagctttgtc gatgaggtgg aggcggcctg gtcggaatac gcagaaggga tgtctggcga
      241 gatcgacgtg gaaggaaaac gcacgttcac ggaatttatc cgtgaaggtg tgggcgttca
      301 tgcgtttaac ggcgaaatct ttgtgcagcc ggtctgggat acggaaacca cgcagttatt
      361 ccgtacgcgt tttaaagccg tgagtccgaa acgggtggac acgccaggac acggtatggg
      421 gaaccgtttt ctgcgggccg gggtggaggt cgatcgatat gg
//
LOCUS       DAZUDJ010000396          462 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.401, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000396 DAZUDJ010000000
VERSION     DAZUDJ010000396.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.401"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>462
                     /gene="espX1"
                     /locus_tag="ACHY1N_005595"
     CDS             <1..>462
                     /gene="espX1"
                     /locus_tag="ACHY1N_005595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector EspX1"
                     /protein_id="HFS4047671.1"
                     /translation="YRCKLIEHTVQFYFFKHKGITLLRLDVFDDRTSECLSEEIKIYQ
                     ECHEKFVNFLKANFNQEIYPQLYTPEIFYEACRNLQSFYDHQETSQNAKYSAIDKKKS
                     HLNQEIKKLIKKNIFPELYNEQCNKIPSSSIDDNQGIMWQNFKTSNIAYSQL"
BASE COUNT          188 a           81 c           65 g          128 t
ORIGIN      
        1 tatagatgta aactcataga acatacagtt caattttatt tttttaaaca caaaggtatc
       61 acattactta gattggatgt ttttgatgac agaacaagcg aatgtctttc tgaagagatt
      121 aagatatacc aagaatgcca tgaaaaattc gttaattttt taaaggcaaa cttcaaccaa
      181 gaaatatacc cacagctata tactcctgaa atattttatg aggcctgcag aaatctccag
      241 tcattttatg atcatcagga aacgtcacaa aacgcaaaat acagtgcaat agacaagaaa
      301 aaaagtcatc ttaaccagga aatcaaaaag cttattaaaa aaaatatttt ccctgagcta
      361 tacaatgagc aatgcaataa aatcccctcc tcatcgatag atgataacca gggaataatg
      421 tggcagaact ttaaaactag caatattgca tattcacaac ta
//
LOCUS       DAZUDJ010000397          459 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.402, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000397 DAZUDJ010000000
VERSION     DAZUDJ010000397.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.402"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..459
                     /locus_tag="ACHY1N_005596"
                     /pseudo
     CDS             1..459
                     /locus_tag="ACHY1N_005596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611997.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSfl10 family transposase"
BASE COUNT          143 a          108 c          116 g           92 t
ORIGIN      
        1 cgtaaggcgt taaatgaagc tcgccttgag cgagatatat taaaaaaagc aacagcgtat
       61 tttgcacagg agtcgctgaa aaatacgcgt taatcgaaca atggcgacaa caatttccca
      121 ttgaagcgat gtgtcaggta tttggtgtat ccaggagcgg ttattacaac tgggtacagc
      181 atgaaccctc agacagaaaa caaagtgatg agcggctaaa actggagatt aaggtggcac
      241 atatccgcac tcgcgaaaca tatggaaccc ggcggctcca gacggagctg gcagagaatg
      301 gcatcatcgt tggtcgtgac cgactggcac gtcttcgtaa ggagctaagg ctacgctgta
      361 agcagaaacg caagttcaga gcgactacga actcgaacca caatctgcca gttgcgccaa
      421 atctgctgaa ccagacgttc gctcctacag caccaaatc
//
LOCUS       DAZUDJ010000398          446 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.403, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000398 DAZUDJ010000000
VERSION     DAZUDJ010000398.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.403"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..332
                     /locus_tag="ACHY1N_005597"
     CDS             <1..332
                     /locus_tag="ACHY1N_005597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4047672.1"
                     /translation="MDSTTRRINESYYKVINNAVYLREYIDEEIKYNDFDCLGEANKL
                     LVSTIWGVFVRYQKWKKKFSDETNGKWREAIKKGMQYIKKINNNKNINLYIKSKMQLY
                     IISKLVS"
     gene            335..>446
                     /locus_tag="ACHY1N_005598"
     CDS             335..>446
                     /locus_tag="ACHY1N_005598"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4047673.1"
                     /translation="MKNLLITIIVASYNSKDYILETLESCINQQYQNIEII"
BASE COUNT          204 a           44 c           64 g          134 t
ORIGIN      
        1 acatggattc aacaacaaga agaataaatg aaagttatta taaagttata aataatgctg
       61 tttatttaag agagtatata gatgaagaaa taaaatataa tgattttgat tgtctaggtg
      121 aagctaataa actccttgta agtactatat ggggagtgtt tgttcgttat caaaaatgga
      181 agaaaaaatt cagtgatgaa acaaacggta aatggcgcga agcaataaaa aaaggaatgc
      241 aatatataaa aaaaatcaat aacaataaga atattaacct gtatattaaa tctaaaatgc
      301 aattatatat aatatctaaa cttgttagct aaatatgaaa aatctattaa ttacaattat
      361 tgttgcatca tataactcaa aagattacat actagagaca ttagagtcat gcattaacca
      421 acaatatcaa aatattgaga ttatta
//
LOCUS       DAZUDJ010000399          432 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.404, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000399 DAZUDJ010000000
VERSION     DAZUDJ010000399.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.404"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
BASE COUNT          125 a           89 c          102 g          116 t
ORIGIN      
        1 atgtcatgat atcgccgtcg ttaacaggta attcttctat gactccagca gacaggcgca
       61 ggcaggaggc ggtcacctga ttactgaaca accttctgac tgacttcagc gtgtcaatca
      121 caggctccac gtcatgcgtc agcatagtgc tgatgctgac ggatgttaca aaaaatgcag
      181 cgtatggcgt tgagatagaa agtctggtgc tggagataaa tacacctaca tcatgataaa
      241 aaagggccag cgactgacct gaagaagaca ctggctaaaa ggctttgcat gtttgtagat
      301 acttattttt cacagacagc aatgatgcct gtcaatatat tattaatatg ctgattgttt
      361 cagttacaga tgctttatta agggaaaatg tcacgatcgg tgcaaaagtg gtttgaaccg
      421 ccccggtttt cc
//
LOCUS       DAZUDJ010000400          427 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.405, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000400 DAZUDJ010000000
VERSION     DAZUDJ010000400.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.405"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..69
                     /locus_tag="ACHY1N_005599"
     CDS             <1..69
                     /locus_tag="ACHY1N_005599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047674.1"
                     /translation="DGPWQDVKGLDEVGSDTGRTGE"
     gene            71..340
                     /locus_tag="ACHY1N_005600"
     CDS             71..340
                     /locus_tag="ACHY1N_005600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310967.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber C-terminal domain-containing
                     protein"
                     /protein_id="HFS4047675.1"
                     /translation="MNILKKLMQRLCGCGKHDGREHVQSLTAQLRLGPADILESDENG
                     IIPEQARVITQVVILDADKKQIQCVVRPLQILRADGRWENIGGMK"
BASE COUNT          120 a           77 c          137 g           93 t
ORIGIN      
        1 gacgggccgt ggcaggatgt taaggggctt gatgaagtgg gcagtgatac aggcagaaca
       61 ggagaatgac atgaatatac taaaaaaact tatgcagcgt ctgtgtggtt gcggaaagca
      121 tgatggccgt gaacacgtgc agtcgcttac agcacagctg cgactgggac cggcagacat
      181 tctggagtcc gatgagaatg gcattatccc ggagcaggcc agggtaatca cgcaggtggt
      241 gatactggat gcggataaaa agcagataca gtgtgtggta agaccgctgc aaatcctgcg
      301 tgctgacggg aggtgggaaa atattggcgg aatgaaatag ccgacagctt cacaaaaacc
      361 ggagtccggc tccggttttt gttgtcatgt catggtgatg tttgttaata aagacttgag
      421 ggaatat
//
LOCUS       DAZUDJ010000401          409 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.406, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000401 DAZUDJ010000000
VERSION     DAZUDJ010000401.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.406"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..100)
                     /locus_tag="ACHY1N_005601"
     CDS             complement(<1..100)
                     /locus_tag="ACHY1N_005601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein E"
                     /protein_id="HFS4047676.1"
                     /translation="MGLFTTRQLLGYTEQKVKFRALFLELFFRRTVN"
     gene            complement(158..>409)
                     /locus_tag="ACHY1N_005602"
     CDS             complement(158..>409)
                     /locus_tag="ACHY1N_005602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HFS4047677.1"
                     /translation="SATPALTPLMLDEASGKLVVWDGQKAGSAVGILVLPLEGTETVL
                     TYYKSGTFATEAIRWPESVDEHKKANAFAGSALSHAALP"
BASE COUNT           91 a          122 c           99 g           97 t
ORIGIN      
        1 aattcaccgt acggcggaaa aacagctcca gaaacagcgc acgaaatttc actttttgtt
       61 cggtataacc gagtaactgg cgggtcgtaa acaatcccat aaatcagttc ctttcattca
      121 gaaatcagtc aggccaccgc ggtggcctga taacgtgtta cggcagcgcc gcgtgactca
      181 gggcactgcc ggcaaaggca tttgcctttt tgtgttcatc cacactttca ggccagcgga
      241 ttgcctccgt cgcaaaggtc cccgacttgt aataggtcag taccgtctct gtgccttcaa
      301 gcggcagtac cagtatgcca actgcactac cggctttctg tccgtcccag accaccagtt
      361 tcccgctggc ttcatccagc atcaggggcg tcagtgccgg tgttgccga
//
LOCUS       DAZUDJ010000402          404 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.407, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000402 DAZUDJ010000000
VERSION     DAZUDJ010000402.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.407"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..152)
                     /locus_tag="ACHY1N_005603"
     CDS             complement(<1..152)
                     /locus_tag="ACHY1N_005603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047678.1"
                     /translation="MSALYERSQLTQVMISSAPATAETMDKAEYLRLDCTIKEVQFTA
                     GQKQDI"
     gene            complement(219..>404)
                     /locus_tag="ACHY1N_005604"
     CDS             complement(219..>404)
                     /locus_tag="ACHY1N_005604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047679.1"
                     /translation="AESSVSVQIDVYAGTVTQARQIRQDAREAIMLLAPGSVSEMQDY
                     IPENRCYRATLEFQVTV"
BASE COUNT           98 a          111 c          103 g           92 t
ORIGIN      
        1 tcaatatcct gtttctgacc ggcggtgaac tggacttcct tgatggtgca gtccaggcgc
       61 agatattccg ccttatccat agtttcagca gtcgccgggg cagatgaaat catcacctgc
      121 gtcagctgtg agcgttcata caaagcagac attctgcctc ctgataataa aaaacccgca
      181 cgcggcgggg tatgggtttt gtagaaaaaa agaaaaagtc acaccgtgac ctgaaactcc
      241 agggttgcac ggtaacagcg gttttccgga atatagtcct gcatttcact gacggatccc
      301 ggggccagca gcattatggc ttcacgggcg tcctgacgta tctgacgcgc ctgcgtcaca
      361 gtcccggcat aaacgtctat ctgcaccgac actgaggact ccgc
//
LOCUS       DAZUDJ010000403          396 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.408, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000403 DAZUDJ010000000
VERSION     DAZUDJ010000403.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.408"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            249..368
                     /locus_tag="ACHY1N_005605"
                     /pseudo
     CDS             249..368
                     /locus_tag="ACHY1N_005605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT           96 a          110 c           71 g          119 t
ORIGIN      
        1 agtgaacttt tgatgatctt tccctaatct cacataggat cagatctcgt ctgatcgttc
       61 cccctgcgct cactaccatg gctctttacc acagcagccg gggttgtttg ggaccgactt
      121 ccgacagcag atcccggtgg gcctgccacc atctcttcac aagcttatgc ttattacatg
      181 caaaacgtcc cgttttgcat ctttgtgcct acggcacacc gatgatcttt ccctgtgatc
      241 tttccctgaa tctgcccctg agaacctgaa tcaaacgtct gactcgcaga accatctgtt
      301 tctcgcgctc tgtagaactt catgaaaaag tcatcggtgc ttttatcgaa aaatacatgt
      361 tctactaatt gaagtcatca tcaaaaaatt taatta
//
LOCUS       DAZUDJ010000404          393 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.409, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000404 DAZUDJ010000000
VERSION     DAZUDJ010000404.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.409"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
BASE COUNT          134 a           83 c           71 g          105 t
ORIGIN      
        1 ataagtgata ttggttgtct ggagattcag ggggccagtc tagtctgtca tgaaacagtt
       61 ttatgacaag acatcaaaaa aatgtcaaaa acgtgatctt tcttcagctt ttcagaatat
      121 tgagtaccag gaagtcaata tcaattctgg gacacatatg catttaccat taaaaccggg
      181 cacaacaagc tgttcagtct caatccatac cccgtgtttt atcaatatca gaataagaat
      241 atctgcggat aaataaaaaa ggaatgtcga gggagcttac cgcagagggc tctccacctc
      301 acaaaccatt tacaaaaatg ataccggcat atctttggtc cctgtcacaa ccagacattg
      361 acaatccaat ataaccccaa atatatttcg ggt
//
LOCUS       DAZUDJ010000405          391 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.410, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000405 DAZUDJ010000000
VERSION     DAZUDJ010000405.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.410"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>391
                     /locus_tag="ACHY1N_005606"
     CDS             <1..>391
                     /locus_tag="ACHY1N_005606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HFS4047680.1"
                     /translation="GQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLYTYPL
                     SPVNSMDPLGLYEFKSKNIDDIGIFALAMCNGESINENKEYGGLICKKQGEYLPMNPI
                     SSNDNDSVDLRNIKCPEGSERVGDYHTH"
BASE COUNT          131 a           63 c           99 g           98 t
ORIGIN      
        1 ggggcagcag tatgatgagg agtccggcct gtattacaac cgccaccgct attatgaccc
       61 gctgcagggg cggtatatca ctcaggatcc gattgggctg aaggggggat ggaacctgta
      121 tacatatccg ctgagcccgg tgaatagcat ggatccatta ggattatatg aatttaaatc
      181 aaaaaatata gatgatattg gaatatttgc attggcaatg tgtaatggag aatcaattaa
      241 cgagaataaa gaatatggtg gactaatatg taagaagcaa ggtgaatatt tacccatgaa
      301 tccgataagt tcaaatgata atgatagtgt agacttgcga aatataaaat gccctgaagg
      361 ttcagagaga gtaggcgatt atcacactca c
//
LOCUS       DAZUDJ010000406          384 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.411, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000406 DAZUDJ010000000
VERSION     DAZUDJ010000406.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.411"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>384
                     /locus_tag="ACHY1N_005607"
     CDS             <1..>384
                     /locus_tag="ACHY1N_005607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HFS4047681.1"
                     /translation="GGRVLAVNSQTRTLTLDREITLPSSGTTLISLVDGQGNPVSVEV
                     QSVTDGVKVKVSRVPDGVAEYSVWGLKLPTLRQRLFRCVSIRENDDGTYAITAVQHVP
                     EKEAIVDNGAHFDGDQSGTVNGVTPP"
BASE COUNT           77 a          112 c          130 g           65 t
ORIGIN      
        1 cggtggtcgc gtgctggcgg tgaacagcca gacccggacg ctgacgctcg accgtgaaat
       61 cacgctgcca tcctccggca ccacgctgat aagcctggtt gacgggcagg gtaatccggt
      121 cagcgtggag gtccagtccg tcaccgacgg cgtgaaggtg aaagtgagcc gtgttcctga
      181 cggcgttgct gaatacagcg tatgggggct gaagttgccg acgttgcgcc agcgcctgtt
      241 ccgctgcgtg agtatccgtg agaacgacga cggcacgtat gccatcaccg ccgtgcagca
      301 tgtacccgaa aaagaagcca tcgtggataa cggggcgcac tttgacggcg accagagcgg
      361 cacggtgaat ggcgtcacgc cgcc
//
LOCUS       DAZUDJ010000407          382 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.412, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000407 DAZUDJ010000000
VERSION     DAZUDJ010000407.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.412"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..187)
                     /locus_tag="ACHY1N_005608"
     CDS             complement(<1..187)
                     /locus_tag="ACHY1N_005608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerB family tellurite resistance protein"
                     /protein_id="HFS4047682.1"
                     /translation="MFGIFKKKTRRAAAEIKKFEKRDLAQAVINAAYLVAYADGECEA
                     SEKAKIEQVLRNQPALSA"
BASE COUNT           86 a          107 c          100 g           89 t
ORIGIN      
        1 acgcagacaa cgcaggctga ttacgtaaga cctgttcgat cttcgctttc tcggatgcct
       61 cgcattcacc atctgcatag gccaccaggt atgcagcgtt aatcaccgcc tgtgccagat
      121 cgcgtttctc aaacttttta atttccgctg ccgctctgcg ggttttcttt ttgaagattc
      181 caaacatcgt gacgttcctt tgggtgggtg agccaacgcc cgggagcgat ctgcccacag
      241 agaaagtcac actgaccact ccgtaagctc acccccgaaa ggctctgtgg ttgatatgcg
      301 ccgggcgtgg cgcagataca aaaaaggccc gccgaagcga gcctggaaaa taagtgtggc
      361 gcgttgtagt ggagtcgaac ca
//
LOCUS       DAZUDJ010000408          377 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.413, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000408 DAZUDJ010000000
VERSION     DAZUDJ010000408.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.413"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>377
                     /locus_tag="ACHY1N_005609"
     CDS             <1..>377
                     /locus_tag="ACHY1N_005609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EF-Tu/IF-2/RF-3 family GTPase"
                     /protein_id="HFS4047683.1"
                     /translation="TGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIK
                     PHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIK
                     MVVTLIHPIAMDDGLRFAIREGGR"
BASE COUNT           91 a           96 c          107 g           83 t
ORIGIN      
        1 actggcgttg aaatgttccg caaactgctg gacgaaggcc gtgctggtga gaacgtaggt
       61 gttctgctgc gtggtatcaa acgtgaagaa atcgaacgtg gtcaggtact ggctaagccg
      121 ggcaccatca agccgcacac caagttcgaa tctgaagtgt acattctgtc caaagatgaa
      181 ggcggtcgtc atactccgtt cttcaaaggc taccgtccgc agttctactt ccgtactact
      241 gacgtgactg gtaccatcga actgccggaa ggcgtagaga tggtaatgcc gggcgacaac
      301 atcaaaatgg ttgttaccct gatccacccg atcgcgatgg acgacggtct gcgtttcgca
      361 atccgtgaag gcggccg
//
LOCUS       DAZUDJ010000409          377 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.414, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000409 DAZUDJ010000000
VERSION     DAZUDJ010000409.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.414"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>377
                     /locus_tag="ACHY1N_005610"
     CDS             <1..>377
                     /locus_tag="ACHY1N_005610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
                     /protein_id="HFS4047684.1"
                     /translation="WFLAGEGESRVTEERPVKSEAQDMLTGEVEQKVTADMMIEFIGQ
                     DGAKTCEELAGKFGVSTRKVASTLAVVTATGRLARVNQNGKFRYCMPGDNLPAEPKAA
                     LVTESDGKAFPQPAGAALPVREAA"
BASE COUNT           93 a           84 c          124 g           76 t
ORIGIN      
        1 tggtttctgg ctggcgaagg tgaatcccgg gtaaccgaag agcggccagt aaaatctgaa
       61 gcacaggata tgctgaccgg ggaggtcgaa caaaaagtta ccgcagacat gatgattgag
      121 tttatcggtc aggatggggc taaaacgtgt gaggaactgg cgggtaagtt cggtgtcagt
      181 actcgcaagg ttgcttccac gctggcggtg gtaaccgcaa cggggcggct ggcacgcgtt
      241 aatcagaacg gtaaatttcg ttactgcatg ccgggcgata atttaccagc agagccgaaa
      301 gccgcgctgg taacggaaag tgatggtaag gcctttcctc agccagcagg tgctgcgtta
      361 ccagtccggg aagccgc
//
LOCUS       DAZUDJ010000410          373 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.415, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000410 DAZUDJ010000000
VERSION     DAZUDJ010000410.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.415"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..297
                     /locus_tag="ACHY1N_005611"
     CDS             <1..297
                     /locus_tag="ACHY1N_005611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HFS4047685.1"
                     /translation="QGFIRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSF
                     GIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALNIWLLVGTALGL"
BASE COUNT           72 a           81 c          115 g          105 t
ORIGIN      
        1 cagggattca ttcgcttcca tatcccgctg tgggtgcgtc gtacagtcac catgttgccg
       61 tcatttattg tcattctgat gggattagat ccgacacgga ttctggttat gagtcaggtg
      121 ctgttaagtt ttggtatcgc cctggcgctg gttccactgc tgattttcac cagtgacagc
      181 aagttgatgg gcgatctggt gaacagcaaa cgcgtaaaac agacaggctg ggtgattgta
      241 gtgctggtcg tggcgctgaa tatctggttg ttggtgggga cggcgctggg attgtagttg
      301 aatgagcgtc gcatctggca ctattggcgg atgcggcgta aacgccttat ccgccctacg
      361 cgttaaagag ccg
//
LOCUS       DAZUDJ010000411          371 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.416, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000411 DAZUDJ010000000
VERSION     DAZUDJ010000411.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.416"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>371)
                     /locus_tag="ACHY1N_005612"
     CDS             complement(<1..>371)
                     /locus_tag="ACHY1N_005612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="POTRA domain-containing protein"
                     /protein_id="HFS4047686.1"
                     /translation="SAGTEGPCFTVSRIVVSGATRLTSAETDRLVAPWVNQCLNITGL
                     TAVTDAVTDGYIRRGYITSRAFLTEQDLSGGVLHITVMEGRLQQIRAEGADLPARTLK
                     MVFPGMEGKVLNLRDIEQGME"
BASE COUNT           73 a          123 c           97 g           78 t
ORIGIN      
        1 tgctccatcc cctgctcaat atcccgcagg ttcagaacct tcccctccat tcccgggaaa
       61 accatcttca gggtgcgggc aggaaggtca gcgccttccg cccggatttg ctgcagcctg
      121 ccttccatga ccgttatgtg cagtacgccc cctgaaaggt cctgctctgt cagaaaggcc
      181 cggctggtga tatatccccg gcgtatatag ccgtccgtca cggcatccgt gaccgcagtc
      241 aggccggtga tattcagaca ctgattcacc cacggtgcca ccagtctgtc ggtttctgca
      301 gacgtcagtc gggtggcccc actgacaaca atgcgtgaca ccgtaaagca ggggccttca
      361 gtaccggcag a
//
LOCUS       DAZUDJ010000412          369 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.417, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000412 DAZUDJ010000000
VERSION     DAZUDJ010000412.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.417"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            170..349
                     /locus_tag="ACHY1N_005613"
     CDS             170..349
                     /locus_tag="ACHY1N_005613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1378 family protein"
                     /protein_id="HFS4047687.1"
                     /translation="MIFLNQLMLYFCTVVCVLYLLSGGYRAVRDCWRRQIDKRAAEKI
                     SAGQSAGSKPEEPLI"
BASE COUNT          110 a           75 c           99 g           85 t
ORIGIN      
        1 ggtggaagtg aacagcacag acactgcggc atgataaaaa aaaccgccag cgacaggaat
       61 ggacgctggc ggtggtgata cctatggaga aaaaataaag gaacgatact ttcgtactct
      121 ggtttttaat gaaaacagtt cttattgtca acaataacgg aaagaaatta tgatatttct
      181 gaaccagtta atgctgtact tctgtacggt ggtctgtgtg ctgtatctcc tttcgggtgg
      241 gtacagggca gtgcgcgatt gctggcgcag gcagattgac aaaagggccg ctgagaaaat
      301 cagcgccggt cagtcagccg gaagcaaacc cgaagagccg ctcatttagc ggcaactttc
      361 ttaatcaca
//
LOCUS       DAZUDJ010000413          367 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.418, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000413 DAZUDJ010000000
VERSION     DAZUDJ010000413.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.418"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>367
                     /locus_tag="ACHY1N_005614"
     CDS             <1..>367
                     /locus_tag="ACHY1N_005614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFS4047688.1"
                     /translation="LPQSNIWPVSIYYRLLSFDYFSARLDSLLYLDADIVCKGSLNEL
                     IALEFKDEYGAVVIDVDAMQSKSAERLCNEDFNGSYFNSGVMYINLREWLKQRLTEKF
                     FDLLSDEPIIKKLKYPDQDT"
BASE COUNT          117 a           47 c           73 g          130 t
ORIGIN      
        1 ctacctcaat caaatatctg gccagtatct atttattatc gtttgctttc atttgattat
       61 ttttctgcgc gattggattc attattatat cttgatgctg atatcgtctg taagggttca
      121 ttgaacgagt taatagcatt agagtttaaa gatgaatatg gggcagtggt aattgatgta
      181 gatgctatgc aaagtaaaag cgctgagcgt ttgtgtaatg aggattttaa cggtagctat
      241 tttaactctg gtgtaatgta tattaattta cgggaatggt taaaacaaag actaacggaa
      301 aaattctttg atctattatc agatgagcca attataaaaa aattaaagta cccggatcaa
      361 gatactt
//
LOCUS       DAZUDJ010000414          366 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.419, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000414 DAZUDJ010000000
VERSION     DAZUDJ010000414.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.419"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..349
                     /locus_tag="ACHY1N_005615"
     CDS             <1..349
                     /locus_tag="ACHY1N_005615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047689.1"
                     /translation="VRISDDQKFDRQVMIPPVLFRGGKHENFNSNNQQSYWYSTCRLR
                     VTRNGQEIFNQSTTDAQGVFSSVIDMPAGQGTLTLTFTVSSSGANNWTPTTSISDLLV
                     VVMKKSTAGISIS"
BASE COUNT          109 a           81 c           87 g           89 t
ORIGIN      
        1 ggtaagaatc agtgatgatc agaaatttga ccggcaggtc atgataccgc cagtgttatt
       61 ccgcggtggt aagcatgaga atttcaacag taataaccaa cagtcatact ggtattcaac
      121 ctgccggtta agagtgaccc gcaatggtca ggagattttt aatcagtcca cgacggatgc
      181 tcagggcgta ttttcctcag ttatagatat gcctgccgga caggggacgc tgacactgac
      241 attcaccgta tcttcatcag gagcgaataa ctggacacca acaaccagta tcagcgatct
      301 gctggttgtg gtgatgaaaa aatccacagc aggtatcagt atcagctgaa ttttataacc
      361 cagaac
//
LOCUS       DAZUDJ010000415          362 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.420, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000415 DAZUDJ010000000
VERSION     DAZUDJ010000415.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.420"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..164)
                     /locus_tag="ACHY1N_005616"
     CDS             complement(<1..164)
                     /locus_tag="ACHY1N_005616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HFS4047690.1"
                     /translation="MRLASRFGYANQIRRDRPLTHEELMHYVPGIFGEDKHTSRSQNY
                     TYIPTITVLE"
     gene            267..>362
                     /locus_tag="ACHY1N_005617"
     CDS             267..>362
                     /locus_tag="ACHY1N_005617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047691.1"
                     /translation="MSEKTVTGEPRIKHLSGIGFRIPAAPASLTFR"
BASE COUNT           79 a           88 c          100 g           95 t
ORIGIN      
        1 ctttccagta cggtgatggt ggggatgtac gtatagttct ggcttcggga cgtgtgttta
       61 tcttccccga aaatccccgg cacatagtgc atcagttctt cgtgtgtcag cggacggtca
      121 cggcgtatct ggttcgcata accaaaacga ctggctagtc gcataatttg ctccttatcg
      181 gtggttaaga tttactggtg taataaatga aaaagccacg tctcccggag aagacgcggc
      241 ctgatgggtg aaatgaatga cgtttattgt ctgagaagac cgtcactggc gagccgcgta
      301 ttaagcacct ttccggcatc gggttcagaa ttccggcagc gccagcgtcg ctgaccttcc
      361 gc
//
LOCUS       DAZUDJ010000416          360 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.421, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000416 DAZUDJ010000000
VERSION     DAZUDJ010000416.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.421"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            122..197
                     /locus_tag="ACHY1N_005618"
     tRNA            122..197
                     /locus_tag="ACHY1N_005618"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Glu,seq:ttc)
BASE COUNT          102 a           82 c           83 g           93 t
ORIGIN      
        1 taaatagcaa ggcgtttacg cgttgggagt gaggctgaag agaataaggc cgttcgcttt
       61 ctattaatga aagctcaccc tacacgaaaa tatcacgcaa cgcgtgataa gcaattttcg
      121 tgtccccttc gtctagaggc ccaggacacc gccctttcac ggcggtaaca ggggttcgaa
      181 tcccctaggg gacgccactt gctggtttgt gagtgaaagt cgccgacccc aatatctcaa
      241 aacagactgt taagtcttgt ttgagatatt tgctctttaa aaatctggat caagctgaaa
      301 attgaaacac tgaacaacga aagttgttcg tgagtctctc aaattttcgc aactctgaag
//
LOCUS       DAZUDJ010000417          359 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.422, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000417 DAZUDJ010000000
VERSION     DAZUDJ010000417.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.422"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..194
                     /locus_tag="ACHY1N_005619"
     CDS             <1..194
                     /locus_tag="ACHY1N_005619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HFS4047692.1"
                     /translation="GVRIEGSSPSLFVRTDTVRAVRRGDTLTINGEIFWVDRVSPDDG
                     GSCYLWLNRGQPPAVNRRR"
     gene            209..>359
                     /locus_tag="ACHY1N_005620"
     CDS             209..>359
                     /locus_tag="ACHY1N_005620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4047693.1"
                     /translation="MAIKGLDQTIENLSRVRKNAIPAASAMAINRVATTAINQSSSQV
                     ARETRV"
BASE COUNT           81 a           86 c          112 g           80 t
ORIGIN      
        1 gcggggtccg tattgaagga agcagcccgt cattatttgt gcggacggat acggttcgtg
       61 ccgtgcggcg tggtgacacg ctgaccatta atggtgagat attctgggtg gatcgtgttt
      121 ctccggatga cgggggcagc tgttatctct ggctcaaccg tggtcaacca cccgccgtta
      181 accggcgacg ataaacgcag ggtgaattat ggcgataaaa gggcttgatc agacgattga
      241 aaatctgagc cgggttcgta aaaacgccat tccggcggct tcagcaatgg ccattaaccg
      301 cgtggccaca acggcgatta atcagtcttc gtcacaggtt gcccgggaaa ccagggtga
//
LOCUS       DAZUDJ010000418          356 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.423, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000418 DAZUDJ010000000
VERSION     DAZUDJ010000418.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.423"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..>356)
                     /locus_tag="ACHY1N_005621"
     CDS             complement(<1..>356)
                     /locus_tag="ACHY1N_005621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4047694.1"
                     /translation="ERIPRELPTGRPAMLHIFEPVEDGQTRGANQFYSVMERLKMLDS
                     LQATQLQSAIVKAMYAATIESELDTEKAFEYIAGAPQEQKDNPLINILEKFSSWYDTN
                     NVTLGGVKIPHLFPGD"
BASE COUNT           79 a          101 c           88 g           88 t
ORIGIN      
        1 catcaccagg gaaaaggtgc ggaattttga caccgcccag tgtcacgtta ttcgtgtcat
       61 accagctgga gaacttctcc agaatattaa taagcggatt atccttctgc tcctgtggcg
      121 cgccggcgat atattcaaag gccttttcgg tatcaagttc actttcaatc gtcgctgcat
      181 acatggcttt cacaatggcc gactgaagct gtgttgcctg cagggaatcc agcatcttca
      241 gccgttccat gacgctgtaa aactgattag ccccacgggt ctgcccgtcc tccaccggct
      301 cgaaaatatg cagcatggcc ggacgcccgg tgggaagttc acgcgggatc cgttcc
//
LOCUS       DAZUDJ010000419          356 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.424, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000419 DAZUDJ010000000
VERSION     DAZUDJ010000419.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.424"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(30..317)
                     /gene="nleC"
                     /locus_tag="ACHY1N_005622"
                     /pseudo
     CDS             complement(30..317)
                     /gene="nleC"
                     /locus_tag="ACHY1N_005622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308874.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector zinc
                     metalloprotease NleC"
BASE COUNT          112 a           71 c           73 g          100 t
ORIGIN      
        1 ccatagctta cggcatcacg aaaagtttat gagcggctca aagcatcaag tatagtatta
       61 ttaatcatat cgaccgtatg ctgatcaatg agtctgccac gactgtcatg gacggcacga
      121 attacacttt cgtatacgtt gcttaaatct gctgcggaaa gtggtattcg cttgcctata
      181 tccaaaacgt aatccgcata ggcattttca gcacgattag gagcaatgag agcagagtat
      241 cctgccgggg cggaaaagtt gaagttggac tgtaatgagg gaattttcat gttgatacct
      301 aataccatgc aaatcattta ttacaacaga ataaacttta tcaaattcat ttacca
//
LOCUS       DAZUDJ010000420          344 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.425, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000420 DAZUDJ010000000
VERSION     DAZUDJ010000420.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.425"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>344
                     /locus_tag="ACHY1N_005623"
     CDS             <1..>344
                     /locus_tag="ACHY1N_005623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFS4047695.1"
                     /translation="AHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHIL
                     LGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKAL
                     EGDAEWEAKILEL"
BASE COUNT           77 a           88 c          105 g           74 t
ORIGIN      
        1 gcacacgtag actgcccggg gcacgccgac tatgttaaaa acatgatcac cggtgctgct
       61 cagatggacg gcgcgatcct ggtagttgct gcgactgacg gcccgatgcc gcagactcgt
      121 gagcacatcc tgctgggtcg tcaggtaggc gttccgtaca tcatcgtgtt cctgaacaaa
      181 tgcgacatgg ttgatgacga agagctgctg gaactggttg aaatggaagt tcgtgaactt
      241 ctgtctcagt acgacttccc gggcgacgac actccgatcg ttcgtggttc tgctctgaaa
      301 gcgctggaag gcgacgcaga gtgggaagcg aaaatcctgg aact
//
LOCUS       DAZUDJ010000421          341 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.426, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000421 DAZUDJ010000000
VERSION     DAZUDJ010000421.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.426"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            43..>341
                     /locus_tag="ACHY1N_005624"
     CDS             43..>341
                     /locus_tag="ACHY1N_005624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HFS4047696.1"
                     /translation="MATQTEVARHLSLTDRQLRRLQKLPGAPISNKRGQLDLDAWRDF
                     YISYLRRSKNDVPDGDSEDDYEEKLLIARWELTAEQAVTQQLKNEVSKGKLIDTG"
BASE COUNT           97 a           59 c          102 g           83 t
ORIGIN      
        1 ttttgttgtg attgtgaggt gagagttttt gcgaggtgag gagtggctac gcagactgaa
       61 gttgccaggc atttaagtct gaccgatcgc cagcttcgca gattgcagaa attgccgggt
      121 gccccgatat cgaataagcg agggcaactg gatctggatg cctggcgcga tttttacata
      181 tcgtatctga ggagaagtaa aaacgatgtg cctgatggcg atagcgaaga cgactatgag
      241 gagaaattgc ttattgccag atgggaactg acagcagaac aggctgttac acagcagtta
      301 aaaaatgagg tgtcaaaagg aaaacttatt gacaccgggt t
//
LOCUS       DAZUDJ010000422          339 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.427, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000422 DAZUDJ010000000
VERSION     DAZUDJ010000422.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.427"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            230..339
                     /locus_tag="ACHY1N_005625"
                     /pseudo
     CDS             230..339
                     /locus_tag="ACHY1N_005625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Hha/YmoA family nucleoid-associated regulatory
                     protein"
BASE COUNT           93 a           67 c           95 g           84 t
ORIGIN      
        1 gcgtatataa aacgtatctg caatgtacgt gaacagagtg cattaagcat ccgtctgagc
       61 ggtaaacata tccgacctgg tgagtgacag tctgagagac cggttaagtg gtggctcggg
      121 agtaatgagt ttggggtggg taccagaatg ccagtctggc ggtatgctga cagtatcacg
      181 ttaattgcag cataaagtga tgagaggcta atggaagtta aaaccaaagc agttccgtcg
      241 ttgttcatcc cgggagacgc tggaaaaagt gatttcccac acgcgttata aacttacctc
      301 tgcggaactg gaagccttca actctgtggt tgatcactg
//
LOCUS       DAZUDJ010000423          338 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.428, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000423 DAZUDJ010000000
VERSION     DAZUDJ010000423.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.428"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(90..242)
                     /locus_tag="ACHY1N_005626"
     CDS             complement(90..242)
                     /locus_tag="ACHY1N_005626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HFS4047697.1"
                     /translation="MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVL
                     AYESKK"
BASE COUNT          104 a           80 c           68 g           86 t
ORIGIN      
        1 attcacataa aaaatataaa ttttaaaaaa gggtgcagga gaccaaacca tcacaattca
       61 gtacgcgggg ttttaccccc gcgtggtggc tacttcttcg attcgtaagc gagaactgcc
      121 ttaaactcca taccacgttc tctgatactc aactcacaca acgagtcacc taccatcagc
      181 gtgaatccca gtactgtaca acacagtacg atgattgcca caagggcata ttttgtcagc
      241 atgtctgtgt aagttcacag agatattgca attgcctccg gataagtaag gggagattgc
      301 actatgcaaa tgcagcatct gatggttggc tatcctaa
//
LOCUS       DAZUDJ010000424          338 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.429, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000424 DAZUDJ010000000
VERSION     DAZUDJ010000424.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.429"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>338
                     /locus_tag="ACHY1N_005627"
     CDS             <1..>338
                     /locus_tag="ACHY1N_005627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFS4047698.1"
                     /translation="SNGEINNLFIKKSNIFGASFTNTRIKNLLCVDIMPGRWTTQLVN
                     KHLGYRYTGVFKTLASIDDKPSRFEILIPLVQTLVRDNVKLNNDVYKELNKFMHDYDK
                     TSSEMRKYLK"
BASE COUNT          131 a           58 c           53 g           96 t
ORIGIN      
        1 tttcaaatgg agaaattaat aatctcttca ttaaaaaaag caacatattt ggagcatcat
       61 tcactaatac cagaataaaa aatttgctct gtgtagatat tatgcctggt cgatggacca
      121 ctcaacttgt caataagcac ttaggttaca gatacacagg agtattcaaa accctggcaa
      181 gtattgatga caaaccgtcc cgtttcgaaa ttttgatacc attggtacaa actttagttc
      241 gcgacaatgt aaagctaaat aatgatgtgt ataaagaact taataagttt atgcacgatt
      301 acgacaaaac atcatcagaa atgagaaaat accttaaa
//
LOCUS       DAZUDJ010000425          333 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.430, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000425 DAZUDJ010000000
VERSION     DAZUDJ010000425.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.430"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..>333
                     /locus_tag="ACHY1N_005628"
     rRNA            1..>333
                     /locus_tag="ACHY1N_005628"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           96 a           72 c          103 g           62 t
ORIGIN      
        1 gttaagcgac taagcgtaca cggtggatgc cctggcagtc agaggcgatg aaggacgtgc
       61 taatctgcga taagcgtcgg taaggtgata tgaaccgtta taaccggcga tttccgaatg
      121 gggaaaccca gtgtgattcg tcacactatc attaactgaa tccataggtt aatgaggcga
      181 accgggggaa ctgaaacatc taagtacccc gaggaaaaga aatcaaccga gattccccca
      241 gtagcggcga gcgaacgggg agcagcccag agcctgaatc agtgtgtgtg ttagtggaag
      301 cgtctggaaa ggcgcgcgat acagggtgac agc
//
LOCUS       DAZUDJ010000426          333 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.431, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000426 DAZUDJ010000000
VERSION     DAZUDJ010000426.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.431"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            205..333
                     /locus_tag="ACHY1N_005629"
                     /pseudo
     CDS             205..333
                     /locus_tag="ACHY1N_005629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453335.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="Hha/YmoA family nucleoid-associated regulatory
                     protein"
BASE COUNT           93 a           68 c           95 g           77 t
ORIGIN      
        1 tgcgtatata aaacgtacca gcaacgcacg tgaacagagt gcattaagca tccgtcgttg
       61 acaccgacct ggtgagtgac agtctgagag accggttaag tggtggtacg ggagtaatga
      121 gtttggggag ggtaccagaa tgtcagtctg gtacggtatg ctgacagtat cacgttaatt
      181 gcagcataaa gtgatgagag gctaatggaa gttaaaacca gagcagttcc gtcgttgttc
      241 atcccgggag acactggaaa aagtgatttc ccacacgcgt tataagctta ctctagcgga
      301 gatggaagcc ttcaactctg cggtcgatca ccg
//
LOCUS       DAZUDJ010000427          326 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.432, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000427 DAZUDJ010000000
VERSION     DAZUDJ010000427.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.432"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>326
                     /locus_tag="ACHY1N_005630"
     CDS             <1..>326
                     /locus_tag="ACHY1N_005630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4047699.1"
                     /translation="ELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDENH
                     QVYGVRKVWRQLLREGIRVARCTVARLMTVMGLAGVLRGKKVRTTVSRKAVSAGDRVN
                     RQFVAER"
BASE COUNT           78 a           82 c           97 g           69 t
ORIGIN      
        1 gagctgcata ttgccccgtc aacgtattac cactgtcagc aacagcgaca tcatcctgat
       61 aaacgcagtg cccgtgctca gcgtgatgac tggctgaaga gagagataca gcgcgtatac
      121 gatgaaaatc atcaggtgta cggtgtgcgt aaagtctggc gccagttgtt acgcgaaggt
      181 atcagggtgg ccagatgtac agtggcgcgc ctcatgactg ttatgggact tgccggtgtt
      241 ctccggggta aaaaggtccg tactaccgtc agccggaaag ccgtttccgc aggcgaccgc
      301 gtaaaccgtc agttcgtggc agaacg
//
LOCUS       DAZUDJ010000428          323 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.433, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000428 DAZUDJ010000000
VERSION     DAZUDJ010000428.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.433"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>323
                     /locus_tag="ACHY1N_005631"
     CDS             <1..>323
                     /locus_tag="ACHY1N_005631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin B"
                     /protein_id="HFS4047700.1"
                     /translation="DTELPVQLNYASVIYGNHGAKYTFLDSGSKAITIHITDESGDYD
                     TFDFRNIVFEHHTNDMFISFDNQGGFVISISNNATNELTDINVFRKNMTSFDGCRSLI
                     YLPSG"
BASE COUNT          105 a           53 c           57 g          108 t
ORIGIN      
        1 gatacggagt tacctgttca acttaattat gctagtgtta tttatggtaa tcatggggca
       61 aaatatacat tcctcgactc aggaagtaaa gctataacca tccacattac tgatgaaagt
      121 ggcgattatg atacttttga cttccgcaat attgtttttg aacatcacac caatgacatg
      181 tttataagct ttgataatca aggaggattt gttatatcaa tatcaaataa tgccacaaat
      241 gaactgacag atattaatgt attccgaaaa aacatgactt cttttgatgg ctgtcgttca
      301 ttgatatatt tgcctagcgg tga
//
LOCUS       DAZUDJ010000429          322 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.434, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000429 DAZUDJ010000000
VERSION     DAZUDJ010000429.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.434"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>322
                     /locus_tag="ACHY1N_005632"
     CDS             <1..>322
                     /locus_tag="ACHY1N_005632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HFS4047701.1"
                     /translation="AGILLVPCCRGGSAFTTGADGTYSDASGASENSTRWGVDKPLYK
                     DLIGRTKAALKKNPKNVLFAVVWMQGEFDFGGTPANHAAQFGALVDKFRADLADMAGQ
                     CVGGS"
BASE COUNT           68 a           72 c          108 g           74 t
ORIGIN      
        1 atgcgggcat tctgctggtt ccgtgctgtc gtggtggttc agcgttcacc accggagccg
       61 atggcacata cagtgacgcg agtggtgcct cggagaattc aacccgctgg ggtgtggaca
      121 agccgctgta taaggacctt atcggtcgaa caaaagcagc actgaagaag aatccgaaaa
      181 atgtgctgtt tgccgtggtg tggatgcagg gggaatttga ttttggcggt acgccggcaa
      241 atcacgcagc acagtttggt gcgctggttg ataaattccg tgcagacctg gcggatatgg
      301 caggtcagtg cgtcggtggc tc
//
LOCUS       DAZUDJ010000430          316 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.435, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000430 DAZUDJ010000000
VERSION     DAZUDJ010000430.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.435"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..266
                     /locus_tag="ACHY1N_005633"
     CDS             <1..266
                     /locus_tag="ACHY1N_005633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="OB-fold-containig protein"
                     /protein_id="HFS4047702.1"
                     /translation="APWLPRDETTALTEEAFIGCMATITGYHAVAGSPCEGRFTDRFG
                     QVHYLLLEPEAGKEFRRGDKVIIVCRLSGSRWLGELNPWPDVL"
BASE COUNT           62 a           84 c           90 g           80 t
ORIGIN      
        1 ttgccccctg gttaccccgt gatgaaacaa cggcgctcac cgaggaggca ttcatcgggt
       61 gtatggccac catcaccggt tatcacgcag tggcgggttc cccctgtgaa ggtcgcttca
      121 cagaccgctt tgggcaggtt cattacctgt tgctggagcc ggaggccggg aaagaattca
      181 gacgaggaga caaagtgatt attgtctgcc gtctttccgg ttcccgctgg ctgggcgaac
      241 tgaatccctg gccggatgtt ctttaatccc gacatataca gaggttctca ctatgtttaa
      301 tcttccggga tggttg
//
LOCUS       DAZUDJ010000431          315 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.436, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000431 DAZUDJ010000000
VERSION     DAZUDJ010000431.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.436"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
BASE COUNT           89 a           55 c          105 g           66 t
ORIGIN      
        1 accttcaccg gcataacaac cggggagaaa cgtaaaaaat aatcgggaat gtgaccgcca
       61 ggagataaac ggggaggtta cggtggctga gccgtaccgg tatgccgggt ggttgttacg
      121 aaacgatgct tccgcacgcg tgcgcgataa agaagggatg attttcgtga ggaagagggg
      181 aaaactggcg ttctgataat tgcagagtta tttacggggc ggttacgatg gggcagaccg
      241 tgtccggtgg gcaggcgaca ggtatcaccg atgggataag actgtctgat tggtattata
      301 aatatataag agaga
//
LOCUS       DAZUDJ010000432          309 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.437, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000432 DAZUDJ010000000
VERSION     DAZUDJ010000432.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.437"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(111..309)
                     /locus_tag="ACHY1N_005634"
                     /pseudo
     CDS             complement(111..309)
                     /locus_tag="ACHY1N_005634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT          108 a           63 c           49 g           89 t
ORIGIN      
        1 catgtataag ctatgaaaaa cagctttagg gaataaggaa tatctcaatt tttaaacata
       61 aaatgcgaat tatttagtac aaaaaagtag cgttacgtga tctttcccta ggatacaact
      121 ctggcaatgg tatcgtgaac aggaatacca ttttcaaaat caccatattg cttcaaaaaa
      181 tcgagatgtg tttccccgaa atcctctata tcttcccaac cttctgcacc agaaataacg
      241 gcacaaatag tcaacagtag aatatctgac aatttatgca ccactttcca ggcttgtctg
      301 taatcgggt
//
LOCUS       DAZUDJ010000433          308 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.438, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000433 DAZUDJ010000000
VERSION     DAZUDJ010000433.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.438"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>308
                     /locus_tag="ACHY1N_005635"
     CDS             <1..>308
                     /locus_tag="ACHY1N_005635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage morphogenesis protein"
                     /protein_id="HFS4047703.1"
                     /translation="DGTAWTPRRRRVTRIQERIRFIWNNEARTLKNWHHDTGKYGRTI
                     TGWDEDKNNIRTFYRDDIDRFLEIRTRRINQDSTKRVPMFVKLRTARYLKARADASGV
                     T"
BASE COUNT           86 a           91 c           82 g           49 t
ORIGIN      
        1 gacgggaccg catggacacc acgcagacgc cgcgtaaccc ggatacagga gcgcattcgc
       61 tttatctgga ataacgaagc acgcacgctg aaaaactggc atcacgacac ggggaaatac
      121 gggcgaacca ttaccgggtg ggatgaggat aaaaacaata tccgcacgtt ttaccgggat
      181 gacatcgacc gttttctgga aatacgcacc cggcgcatca accaggacag cacaaagcgc
      241 gtccccatgt tcgtaaaact gcgcaccgcc cgctacctga aagcccgtgc agatgcttcc
      301 ggtgtgac
//
LOCUS       DAZUDJ010000434          308 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.439, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000434 DAZUDJ010000000
VERSION     DAZUDJ010000434.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.439"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..242)
                     /locus_tag="ACHY1N_005636"
     CDS             complement(<1..242)
                     /locus_tag="ACHY1N_005636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HFS4047704.1"
                     /translation="MDKKQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSI"
BASE COUNT           91 a           59 c           66 g           92 t
ORIGIN      
        1 ttaatggata aatccatcaa tttgtggaca ttttcgtcgt cccaggtctg gcagaaagtg
       61 gccaggttct gacgagcgtt gccatcaaga tataattcgt cattgataat ctggaatgcg
      121 acatcgtcgc gcatttcgtg cagcggaaaa cgttttgatt ctgcgatagt ggaaatagac
      181 ttcgcaccaa aacgtgaatc gagtagttcc gaccttaaat ccgttacttg cttcttatcc
      241 attttaaact ccttaaaatg attggatcgc attaaaaaag taggatttat cgataaagta
      301 agcaagtg
//
LOCUS       DAZUDJ010000435          307 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.440, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000435 DAZUDJ010000000
VERSION     DAZUDJ010000435.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.440"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(<1..136)
                     /locus_tag="ACHY1N_005637"
     CDS             complement(<1..136)
                     /locus_tag="ACHY1N_005637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TA system toxin CbtA family protein"
                     /protein_id="HFS4047705.1"
                     /translation="MKTLPDTHVREASSCPSPVTIWQTLLSRLLGQHYGLTLNDTPFA
                     D"
     gene            complement(226..>307)
                     /locus_tag="ACHY1N_005638"
     CDS             complement(226..>307)
                     /locus_tag="ACHY1N_005638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051495 - positive regulation of
                     cytoskeleton organization [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HFS4047706.1"
                     /translation="LTCKADTLGSGGYVYLAVYPTPETKK"
BASE COUNT           75 a           63 c           97 g           72 t
ORIGIN      
        1 catcggcgaa cggtgtgtca ttcagtgtaa ggccgtaatg ctggcccagt agtcgggaga
       61 gcagagtctg ccagatggtg acgggagacg ggcagctcga tgcctcccgt acgtgtgtat
      121 cgggtaatgt tttcatactg aaggttttcc tgatatgcag agatgaaaaa tggaaaagtg
      181 gcgtggtgaa agcaccaggc cggagcagaa ggttattccg gtggtttact ttttcgtttc
      241 gggcgtcgga taaacagcca gataaacgta accaccgcta ccgagagtgt cagctttgca
      301 ggtcaga
//
LOCUS       DAZUDJ010000436          306 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.441, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000436 DAZUDJ010000000
VERSION     DAZUDJ010000436.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.441"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..306
                     /locus_tag="ACHY1N_005639"
                     /pseudo
     CDS             1..306
                     /locus_tag="ACHY1N_005639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312389.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          117 a           50 c           50 g           89 t
ORIGIN      
        1 caagataagc attcagataa agttaacagt catcaacacc atggcaaggt tgataaaaaa
       61 tatcgatcaa acacagttta agttaatatg ctgaatgact tttcgcaaat agataacgat
      121 ttaggcctga atatcatcta tttcctgcaa catggtcact ggagggtaaa tgaacatagt
      181 cttcagatgg agaaaatatg gttttacaat agtgagccat ctatagatat tcaagaatat
      241 aatagtttcg ccaagaatac tactaacacg tttatcttta caattatacc agacaataac
      301 tatgtg
//
LOCUS       DAZUDJ010000437          293 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.442, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000437 DAZUDJ010000000
VERSION     DAZUDJ010000437.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.442"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..237
                     /gene="cdiI4"
                     /locus_tag="ACHY1N_005640"
     CDS             <1..237
                     /gene="cdiI4"
                     /locus_tag="ACHY1N_005640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDI system immunity protein CdiI-o11"
                     /protein_id="HFS4047707.1"
                     /translation="TLMEKYGYRTKRALFKNMKKVGIHLVNDVITIRPSFHEKLEAWS
                     GNRINESDYVVLPADSSPTEIGSGLRLALSRCKG"
BASE COUNT           83 a           64 c           66 g           80 t
ORIGIN      
        1 actctgatgg agaagtatgg ttatagaact aaacgtgcat tatttaaaaa catgaaaaaa
       61 gttggtatcc atctggtaaa tgatgttatc acaatccggc cttcattcca tgaaaagctg
      121 gaagcatgga gtggtaacag gatcaatgaa tctgactatg tggtgcttcc tgcagacagt
      181 tccccaaccg aaatcggctc aggtcttcgc ctggccttga gtcgctgcaa aggttaacct
      241 agatatcccg cccatcactg gcgggatttt tgtgtgcttc caagcatatc atc
//
LOCUS       DAZUDJ010000438          283 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.443, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000438 DAZUDJ010000000
VERSION     DAZUDJ010000438.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.443"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..>283
                     /locus_tag="ACHY1N_005641"
     CDS             <1..>283
                     /locus_tag="ACHY1N_005641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase gpA endonuclease subunit"
                     /protein_id="HFS4047708.1"
                     /translation="GLKTFVNTTLGETWEEAVGEKLDHQVLMDKVVRYTAAVPARVVY
                     LTAGIDSQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDAAI"
BASE COUNT           62 a           59 c          101 g           61 t
ORIGIN      
        1 ggcctgaaaa cctttgtgaa caccacgctg ggcgagacct gggaagaggc cgtgggcgaa
       61 aaactcgatc accaggtact gatggataag gtggtgcgtt acacggcggc ggtgcctgcc
      121 cgggtggttt atctgacggc gggcattgac tcgcagcgaa accgttttga gatgtatgtc
      181 tggggatggg ctccgggaga ggaagccttt ctggtggata aaatcatcat tatggggcgt
      241 cctgatgagg aagagacgct gttacgtgtg gatgcggcga tca
//
LOCUS       DAZUDJ010000439          281 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.denovo.444, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000439 DAZUDJ010000000
VERSION     DAZUDJ010000439.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.denovo.444"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            1..281
                     /locus_tag="ACHY1N_005642"
                     /pseudo
     CDS             1..281
                     /locus_tag="ACHY1N_005642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611435.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           74 a           71 c           79 g           57 t
ORIGIN      
        1 gcccggcaac atggtgtagc agccagccag ttatttctct ggcgtaagca ataccaggaa
       61 ggaagtctta ctgctgtcgc cgccggagaa caggttgttc ctgcctctga acttgctgcc
      121 gccatgaagc agattaaaga actccagcgc ctgctcggca agaaaacgat ggaaaatgaa
      181 ctcctcaaag aagccgttga atatggacgg gcaaaaaagt ggatagcgca cgcgccctta
      241 ttgcccgggg atggggagta agcttagtca gccgttgtct c
//
LOCUS       DAZUDJ010000440        12025 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.guided.108, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000440 DAZUDJ010000000
VERSION     DAZUDJ010000440.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12025
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.guided.108"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..619
                     /locus_tag="ACHY1N_005643"
     CDS             <1..619
                     /locus_tag="ACHY1N_005643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HFS4047709.1"
                     /translation="GQSILQRHIASFSHHGLPQGSDDALRYIAEHDDALAFACINRQM
                     IALRIMQQVKATGSPVLDVAHNFVSACQIGEQQGWLHRKGATPDDNGLVIIPGSRGDY
                     SWIVQPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICRDKQL
                     IFEEAPQAYKSAESVVQCLVQAGLIIPVARLRPVLTLKNSGGKKG"
     gene            616..1230
                     /gene="prfH"
                     /locus_tag="ACHY1N_005644"
     CDS             616..1230
                     /gene="prfH"
                     /locus_tag="ACHY1N_005644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HFS4047710.1"
                     /translation="MILLQLSSAQGPEECCLAVKKALDRLIKEAARQDVAVTVLETET
                     GRYSDTLRSALISLDGDNAWALSESWCGAIQWICPSPYRPHHGRKNWFLGIGRFTADE
                     QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWKLEQQQQENSAVLKSQRRMFHHQIERGNPRRTFTGMAFIEG"
     gene            complement(1287..2744)
                     /gene="pepD"
                     /locus_tag="ACHY1N_005645"
     CDS             complement(1287..2744)
                     /gene="pepD"
                     /locus_tag="ACHY1N_005645"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HFS4047711.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVL
                     KSLMNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            3005..3463
                     /gene="gpt"
                     /locus_tag="ACHY1N_005646"
     CDS             3005..3463
                     /gene="gpt"
                     /locus_tag="ACHY1N_005646"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000310 - xanthine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFS4047712.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            3555..4799
                     /gene="frsA"
                     /locus_tag="ACHY1N_005647"
     CDS             3555..4799
                     /gene="frsA"
                     /locus_tag="ACHY1N_005647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HFS4047713.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDDA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITGWIEKRLC"
     gene            4857..5258
                     /gene="crl"
                     /locus_tag="ACHY1N_005648"
     CDS             4857..5258
                     /gene="crl"
                     /locus_tag="ACHY1N_005648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045893 - positive regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HFS4047714.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     gene            complement(5297..6352)
                     /gene="phoE"
                     /locus_tag="ACHY1N_005649"
     CDS             complement(5297..6352)
                     /gene="phoE"
                     /locus_tag="ACHY1N_005649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HFS4047715.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     gene            6640..7743
                     /gene="proB"
                     /locus_tag="ACHY1N_005650"
     CDS             6640..7743
                     /gene="proB"
                     /locus_tag="ACHY1N_005650"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFS4047716.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            7755..9008
                     /gene="proA"
                     /locus_tag="ACHY1N_005651"
     CDS             7755..9008
                     /gene="proA"
                     /locus_tag="ACHY1N_005651"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFS4047717.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLGEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGSVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     gene            9123..9198
                     /locus_tag="ACHY1N_005652"
     tRNA            9123..9198
                     /locus_tag="ACHY1N_005652"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9156..9158,aa:Thr,seq:cgt)
     gene            complement(9325..9663)
                     /locus_tag="ACHY1N_005653"
                     /pseudo
     CDS             complement(9325..9663)
                     /locus_tag="ACHY1N_005653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014831000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
     gene            complement(9714..10670)
                     /gene="paoD"
                     /locus_tag="ACHY1N_005654"
     CDS             complement(9714..10670)
                     /gene="paoD"
                     /locus_tag="ACHY1N_005654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor insertion chaperone PaoD"
                     /protein_id="HFS4047718.1"
                     /translation="MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAVLV
                     TLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEAAAAFEALEMMGSGRDREIRYGE
                     GSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPAGLRYDPQAQSLVCLPTQ
                     TRTGWNLNGFEVGFRPCVRLMIYGRSLETQATASLAAATGYDSHIFDLFPASASAQID
                     TDTAVILLCHDLNRELPVLQAAREAKPFYLGALGSYRTHTLRLQKLHELGWSREETTQ
                     IRAPVGIFPKARDAHTLALSVLAEVASVRLHQEEDSCLPPSS"
     gene            complement(10680..>12025)
                     /gene="paoC"
                     /locus_tag="ACHY1N_005655"
     CDS             complement(10680..>12025)
                     /gene="paoC"
                     /locus_tag="ACHY1N_005655"
                     /EC_number="1.2.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aldehyde oxidoreductase molybdenum-binding
                     subunit PaoC"
                     /protein_id="HFS4047719.1"
                     /translation="LQHLRIGADQSGKITAISHESWSGNLPGGTPETAVQQSELLYAG
                     ANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQV
                     DPADPTRCFSRRQLIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLE
                     KSGARVHLEQNGTVTVETDMTDIGTGSYTILAQTAAEMLGVPLEQVAVHLGDSSFPVS
                     AGSGGQWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEAT
                     AGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNP
                     KTARSQVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDD
                     TDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPITLDKLLDKLPDVV"
BASE COUNT         2812 a         3122 c         3231 g         2860 t
ORIGIN      
        1 ggggcagtct attttacagc ggcatattgc ctcgttctcg catcatggtt tgcctcaagg
       61 cagtgacgac gcgctacggt atattgcgga acatgacgat gcgctggcgt ttgcgtgtat
      121 taatcgccag atgatcgctt tgcgcataat gcaacaagtt aaggccacgg gaagtccggt
      181 tctggatgtg gcgcataact ttgttagcgc gtgtcaaatc ggcgagcaac agggctggtt
      241 gcatcgtaaa ggtgccacgc cggatgacaa cggtctggtg attattcccg gttcacgtgg
      301 tgattactcc tggattgtac agcctgttgc gaacgaaaaa acgctccact cgctggcgca
      361 tggggcaggg cgtaaatggg ggcgcaccga gtgtaaaggg cgtctggcag cgaaatacac
      421 ggcgacgcaa ctctcgcgta ctgaacttgg cagtcgggta atttgtcgcg ataaacaact
      481 catctttgaa gaagcgccac aagcctataa atcggctgaa agcgtggtgc aatgtctggt
      541 gcaggccggt ttaattattc ctgtcgcgcg gctgcgtccg gtgctaacgc tcaaaaacag
      601 tggagggaaa aaaggatgat cttgctacaa ctctcctcag cgcaggggcc ggaagaatgt
      661 tgtctcgcag tgaaaaaggc gctggacagg cttattaaag aagctgcccg acaagacgtc
      721 gcggtaacgg tgttggaaac agaaacgggc cgctactctg acacgctgcg ttcggcgctg
      781 atttctctgg atggcgataa cgcatgggca ttaagcgaaa gctggtgtgg cgctattcag
      841 tggatttgtc cgagtccgta tcggcctcat catgggcgca aaaactggtt tctgggcatt
      901 gggcgtttta ccgctgatga gcaggaacaa tcggatgcaa tccgttatga gacgttgcgt
      961 tcgtcggggc cgggcggtca acatgtcaat aaaaccgact cggcggtacg cgccacgcat
     1021 ttggcatccg gtattagcgt gaaggttcag tcagagcgta gtcagcatgc taacaagcgg
     1081 ctggcacgat tgctgattgc ctggaagctg gagcagcagc aacaggaaaa tagcgcggtg
     1141 ctgaaatcgc agcggcgaat gttccatcac cagattgaac gtggcaaccc gagacggaca
     1201 tttacaggga tggcttttat cgaaggataa tgaaggatga aactgccgga aggcgattaa
     1261 acgccatccg gcagcaaatc aaataattac ttcgccggaa tttctttcag cagttcagtc
     1321 agcagcgtcc agtaatgacc tacgctttcg atgtgaactt gctcatccgg agagtgtgga
     1381 ccggtgatag ttggcccgat agaaaccatg tccatttccg gatacggttt tttgaacaga
     1441 ccacattcca ggcccgcgtg gataatctgg atgttcggtg ttttgttgaa cagacgctga
     1501 taggtttcac gtaccagatg catcaccgga gaattagcgt ccggctgcca gccaggatat
     1561 gcgcctttcg cttcggtttt cgcgccagcc agtttaccca gcgaatccag catgctcacg
     1621 acgtagtctt taccgctgtc gatcagtgaa cggatcagac agtgaatttc tacgttatta
     1681 tcagtcatgg tcaccacacc gacgttcagg gaggtttcga ccacaccttt tgccacgtct
     1741 gagttgcgga tcacaccgtt cggggtggcg ttcagcagac gaataaaggt atcgcgagat
     1801 ttcgcaatca gggcagcttt atcgttcgct acagagtcca gcaacaaggc cagatttttc
     1861 tctttctctg ccagctcgtt tttcaggatc tcctgatagg tattcatcag agatttcagg
     1921 acgtcgactt tatcagctgc gacagcaatg gtcgcaaagg cttcacgcgg gatggcgtta
     1981 cgcagtgtgc cgccgttgaa atcgataagg cgcagatcca gttcttctgc atgacccgcc
     2041 aggaagcgca ccagcagttt gttggcatta cccaggccaa cgtggatttc cccgccggag
     2101 tgaccccctt tcagaccttt taaggttaac ttgaaggttt caaaaccagc tggaaccgct
     2161 tcacgatcta aatgcaggtt ggaggtgaag tcgatacccc ccgcacaacc catgtagatt
     2221 tcaccttctt cttcggagtc ggtgttaatc agaatatcag cctgcaacca gttgctctgt
     2281 aagccgaacg caccgtccat accggcttct tcggtcatgg tcagcagcac ttccagcggg
     2341 ccgtgaacca cgttttcgtc agccagaact gccagtgcag aggccatacc aatgccgtta
     2401 tccgcaccca gcgtggtgcc gcgcgcttta acccattcgc catcaatata aggctggata
     2461 ggatctttcg tgaagtcatg cacggtgtcg ttatttttct gcggcaccat atcgaggtgg
     2521 gcctgtaaga cgaccggttt acgattttcc atacctgcgg tagcaggttt acgaatcagg
     2581 atattaccta cctgatcgcg ttcgacatgg aaacctttct cttttgccca accaacaatg
     2641 tattcagcga gttgctcttc atgataggac gggtgaggaa tagaacagat tttggcaaaa
     2701 atatcccaca gcggctgtgg agataattga gacagttcag acacgttaag tctccttgtc
     2761 gatcacccgc aaaacagtat tgcaggtcac agggttagca gaaaatgttg tcaacacaag
     2821 acaggcttgc gagatatgtt tgagaatacc actttatccc gcgtcaggga gaggcagtgc
     2881 gtaaaaagac gcggactcat gtgaaatact ggtttttagt gcgccagatc tctataatct
     2941 cgcgcaacct attttcccct cgaacacttt ttaagccgta gataaacagg ctgggacact
     3001 tcacatgagc gaaaaataca tcgtcacctg ggacatgttg cagatccatg cacgtaaact
     3061 cgcaagccga ctgatgcctt ctgaacaatg gaaaggcatt attgccgtaa gccgtggcgg
     3121 tctggtaccg ggtgcgttac tggcgcgtga actgggtatt cgtcatgtcg ataccgtttg
     3181 tatttccagc tacgatcacg acaaccagcg cgagcttaaa gtgctgaaac gtgcagaagg
     3241 cgatggcgaa ggcttcatcg ttattgatga cctggtggat accggtggta ctgcggttgc
     3301 gattcgtgaa atgtatccaa aagcgcactt tgtcaccatc ttcgcaaaac cggccggtcg
     3361 cccgctggtt gatgattatg ttgttgatat cccgcaagat acctggatcg aacagccgtg
     3421 ggatatgggc gtcgtattcg tcccgccaat ctccggtcgc taatcttttc aacgcctggc
     3481 actgccgggc gttgttcttt ttaacttcag gcgggttaca atagtttcca gtaagtattc
     3541 tggaggctgc atccatgaca caggcaaacc tgagcgaaac cctgttcaaa ccccgcttta
     3601 aacatcctga aacctcgacg ctagtccgcc gctttaatca cggcgcacaa ccgcctgtgc
     3661 agtcggctct tgatggtaaa accatccctc actggtatcg catgattaac cgtctgatgt
     3721 ggatctggcg cggtattgac ccacgtgaaa tcctcgacgt ccaggcacgt attgtgatga
     3781 gcgatgctga acgtaccgac gatgatttat acgatactgt gattggctac cgtggtggca
     3841 actggattta tgagtgggcc acccaggcga tggtgtggca acaaaaagcc tgtgcggaag
     3901 aagatccgca actcagtggt cgacactggc tgcatgcggc tacgttgtac aacattgccg
     3961 cctatcctca tctgaaagga gatgacctgg ccgagcaagc gcaggcttta tcaaaccgcg
     4021 cctatgaaga ggccgcccag cgtctgccgg gcacgatgcg gcagatggag tttaccgtac
     4081 ccggcggtgc gcccatcacc ggctttttgc atatgccgaa aggcgatggc ccgttcccga
     4141 cagtattaat gtgtggtggt ctggatgcga tgcagacgga ctattacagc ctgtatgaac
     4201 gttattttgc gccgcgcggc attgcgatgc tgactattga tatgccgtcg gtgggctttt
     4261 cttcaaaatg gaagctcacc caggactcca gcctgttgca tcagcacgtc ttaaaggcgc
     4321 tgcctaacgt accgtgggtg gatcacactc gcgtcgcggc ctttggtttc cgtttcggcg
     4381 ctaacgttgc cgtgcgtctg gcataccttg aatcgccgcg tctgaaagcg gttgcctgtc
     4441 ttggtccggt agttcatacc ctgttgagtg attttaagtg ccagcaacag gtgccggaaa
     4501 tgtatcttga cgttctggcg agtcgtttgg ggatgcatga tgcttccgat gacgcgttgc
     4561 gcgtggagct gaatcgctat tcattaaaag tgcaaggatt gctgggacgt cgctgcccaa
     4621 cgccaatgtt atcaggctac tggaagaacg atccgttcag cccggaagag gactcacgct
     4681 taatcacctc atcatctgct gacggtaaat tattagagat cccatttaac ccggtgtatc
     4741 ggaattttga caaaggtctt caggaaatca ccggctggat cgaaaaacgc ttgtgttaaa
     4801 aatttgctaa attttgccaa tttggtaaaa cagttgcatc acaacaggag atagcaatga
     4861 cgttaccgag tggacacccg aagagcagat tgatcaaaaa atttaccgca ctaggcccgt
     4921 atattcgtga aggtaagtgc gaagataatc gattcttttt cgattgtctg gctgtatgcg
     4981 tcaacgtgaa accggcaccg gaagtgcgtg aattctgggg ctggtggatg gagctggaag
     5041 cgcaggaatc ccgttttacc tacagctacc agtttggtct gttcgataaa gcaggcgact
     5101 ggaagagcgt tccggtaaaa gacactgaag tggttgaacg actggagcac accctgcgtg
     5161 agtttcacga gaagctgcgt gaactgctga cgacgctgaa tctgaagctg gaaccggcgg
     5221 atgattttcg tgacgagccg gtgaagttaa cggcgtgagt gaaatgtgcc ggatgcatca
     5281 catccggcaa taatcattaa aactgatagg tcatgccaac cgcgacaata tcatcattat
     5341 taatattcaa tttgttatcg ctatccagtt ggttgatttt ataatcaaca aacgctgaca
     5401 tatttttgtt gaaataatat gtagccccga catcgatata attgaccaga tcttcatcac
     5461 cgataccttc aatatctttc cctttcgata agacataacc cagcgatgga cgcagaccaa
     5521 agtcaaactg gtattgagcg accgcttcaa agttctgtgt cttattggca aagccgccag
     5581 ttattggcgt cattttgcgt gtttcagaat aaaaagttgc cagataaata ttattggcat
     5641 cgtatttcag acctgttgcc catgcttctg cacgcttgcc agtgccacgg ctttgcaggt
     5701 tctgctcgtt ggtgcgatct gagttggtat aggcaccact aatggcgaaa tcgctgccgc
     5761 caaagtcata tgtcaatgac gtgccgaagc catcgccgtt ttgcttttta acgtcgcggt
     5821 tttcgttttt cccttgatat tgcagggtta agttcaggcc atcgataacg ccgaagaagt
     5881 cggtgttccg atacgtcgcc agaccgctgg cgcgtttggt cataaagttg tcggtctgcg
     5941 ccgaggagtc gccaccaaat tccgggaaca tatcggtcca ggcttccacg tcatacaacg
     6001 cgcccaggtt acggccatag tcgaaagaac ccaaatcttt atacttcaat ccggcaaaag
     6061 cgagacgcgt tttttgctgt gcagtatcac tctccgcttt atttccggca aactccgctt
     6121 cccaacggcc atagccagtc agttgatcgt taatttgtgt ttcgccttta aaaccaaaac
     6181 ggatataact ctggtcgcca tctttactgt cgttatcact catataatgc atggctttaa
     6241 ctttgccata gacatccagt ttattaccgt ctttgttata tatttctgcg gcctgtacgg
     6301 atgcagatgc cacaatgccc atcaccacta atgccagagt gctctttttc attttcattc
     6361 ctgattttaa ttaacgcgcg aatattcagc gggagagccc cgttgaaaac aggaaagttt
     6421 ttaacctgag attgttaaag atatattaca gattaataat attcttaaaa tgtggtaatt
     6481 tattaaatct gtaataaaag cgtaaacaac tgccgctagg cttgctgatc ccgcgcaaca
     6541 aaacgccatg ctttgcttgc agatggttgg caaccgacga cagtcctgct aaaacgttcg
     6601 tttgatatca tttttcctaa aattgaatgg cagagaatca tgagtgacag ccagacgctg
     6661 gtggtaaaac tcggcaccag tgtgctaaca ggcggatcgc gccgtctgaa ccgtgcccat
     6721 atcgttgaac ttgttcgcca gtgcgcgcag ttacatgccg ccgggcatcg gattgttatt
     6781 gtgacgtcgg gcgcgatcgc cgccggacgt gagcacctgg ggtacccgga actgccagcg
     6841 actatcgcct cgaaacaact gctggcggcg gtagggcaga gtcgactgat tcaactgtgg
     6901 gaacagctgt tttcgattta tggcattcac gtcgggcaga tgctgctgac ccgtgctgat
     6961 atggaagacc gtgaacgctt cctgaacgcc cgcgacaccc tgcgtgcgtt gctcgataac
     7021 aatatcgttc cggtaatcaa tgagaacgat gctgtcgcta cggcagagat taaggtcggc
     7081 gataacgata acctttctgc gctggcggcg attctggcgg gtgccgataa actgttgctg
     7141 ctgaccgatc aaaaaggttt gtataccgct gatccgcgca gcaatccgca ggcagaactg
     7201 attaaagatg tttacggcat tgatgacgca ctgcgcgcga ttgccggtga cagcgtttca
     7261 ggcctcggaa ctggcggcat gagtaccaaa ttgcaggccg ctgacgtggc ttgccgtgcg
     7321 ggtatcgaca ccattattgc cgcgggcagc aagccgggcg ttattggtga tgtgatggaa
     7381 ggcatttccg tcggtacgct gttccatgcc caggcgactc cgcttgaaaa ccgtaaacgc
     7441 tggattttcg gtgcgccgcc ggcgggtgaa atcacggtag atgaaggggc aactgccgcc
     7501 attcttgaac gcggcagctc cctgttgccg aaaggcatta aaagcgtgac tggcaatttc
     7561 tcgcgtggtg aagtcatccg catttgcaac ctcgaaggtc gcgatatcgc ccacggcgtc
     7621 agtcgttaca acagcgatgc attacgccgt attgccgggc accactcgca agaaattgat
     7681 gcaatactgg gatatgaata cggcccggtt gccgttcacc gtgatgacat gattacccgt
     7741 taaggagcag gctgatgctg gaacaaatgg gcattgccgc gaagcaagcc tcgtataaat
     7801 tagcgcaact ctccagccgc gaaaaaaatc gcgtgctgga aaaaatcgcc gatgaactgg
     7861 aagcacaaag cgaaatcatc ctcaacgcta acgcccagga tgttgctgac gcgcgtgcca
     7921 atggccttgg cgaagcgatg cttgaccgtc tggcactgac gcccgcacgg ctgaaaggca
     7981 ttgccgatga tgtgcgccag gtgtgtaacc tcgccgatcc ggtggggcag gtaatcgatg
     8041 gcagcgtact ggacagcggc ctgcgtcttg agcgtcgtcg cgtaccgctg ggggttattg
     8101 gcgtgattta tgaagcgcgc ccgaacgtga cggttgatgt cgcttcgctg tgcctgaaaa
     8161 ccggtaatgc ggtgatcctg cgcggtggca aagaaacgtg tcgcactaac gctgcaacgg
     8221 tggcggtgat tcaggacgcc ctgaaatcct gcggcttacc ggcgggtgcc gtgcaggcga
     8281 ttgataatcc tgaccgtgcg ctggtcagtg aaatgctgcg tatggataaa tacatcgaca
     8341 tgctgatccc gcgtggtggc gctggtttgc ataaactgtg ccgtgaacag tcgacaatcc
     8401 cggtgatcac aggtggtata ggcgtatgcc atatttacgt tgatgaaagt gtagagatcg
     8461 ctgaagcatt aaaagtgatc gtcaacgcga aaactcagcg tccgagcaca tgtaatacgg
     8521 ttgaaacgtt gctggtgaat aaaaacatcg ccgatagctt cctgcccgca ttaagcaaac
     8581 aaatggcgga aagcggcgtg acattacacg cagatgcagc tgcactggcg cagttgcagg
     8641 caggccctgc gaaggtggtt gctgttaaag ccgaagagta tgacgatgag tttctgtcat
     8701 tagatttgaa cgtcaaaatc gtcagcgatc ttgacgatgc catcgcccat attcgtgaac
     8761 acggcacaca acactccgat gcgatcctga cccgcgatat gcgcaacgcc cagcgttttg
     8821 ttaacgaagt ggattcgtcc gctgtttacg ttaacgcctc tacgcgtttt accgacggcg
     8881 gccagtttgg tctgggtgcg gaagtggcgg taagcacaca aaaactccac gcgcgtggcc
     8941 caatggggct ggaagcactg accacttaca agtggatcgg cattggtgat tacaccattc
     9001 gtgcgtaaat aaaaccgggt gatgcaaaag tagccatttg attcacaagg ccattgacgc
     9061 atcgcccggt tagttttaac cttgtccacc gtgattcacg ttcgtgaaca tgtcctttca
     9121 gggccgatat agctcagttg gtagagcagc gcattcgtaa tgcgaaggtc gtaggttcga
     9181 ctcctattat cggcaccatt aaaatcaaag agttacccca tatttaaata caccacgttt
     9241 cctcctgtgc cgcatttgtg ccattgtaac cttggcaatt catcaaaata ctgttctgac
     9301 atcaggcagt gcaggtgcag ctatttaaac caattgctgc cgccattctt tgacgtagtc
     9361 aatcagggcg cggagctttg gtgcaatatt gcgacgctgt gggaaataca gatagaagcc
     9421 cggaaattgt ggaagaaagt catcaagcag cgatacaagc ttaccgcttt caatatatgg
     9481 cctgaaagtt tcctgagtgg caattgttat tcctccgccg gcaagagcca gcctcaacat
     9541 cagacgcaga tcattagtcg taatctgcgg ttcaatcgca aggtcgaaag ttctcccgtt
     9601 ttcttcaaat ggccagcgat aaggcgcaac ctccggggac tgacgccagc cgatacactt
     9661 atgggtattt cccccggagg cgagaaagcg ctctccacgc ccggccgcaa ggatcaggac
     9721 gacgggggca ggcatgaatc ctcctcctga tggagacgta cagaggcgac ttctgccagc
     9781 acggagagtg ccagagtatg cgcatcccgg gctttgggga atatcccgac gggtgcccgg
     9841 atttgcgttg tttcctccct ggaccatccc agctcgtgga gcttttgcag acgtaacgtg
     9901 tgggttcgat agctgcccaa tgcgccgaga taaaagggtt ttgcttctcg cgcggcctgc
     9961 aacactggca gctcccggtt gagatcatgg cacagcaaaa tgaccgccgt atcggtatcg
    10021 atctgagcgc tggctgaggc cggaaaaaga tcgaagatat ggctgtcata gcctgtggct
    10081 gctgcaagac tcgcagttgc ctgcgtctca agagaacgtc cgtaaatcat cagcctgacg
    10141 catggcctga accccacctc aaagccattg agattccagc ccgttcgggt ttgcgtgggc
    10201 aggcacacca gcgattgtgc ttgcggatcg tagcgcagcc ccgccggttt tctctgttcc
    10261 agacggttca gcacggcgag cagaggctgt gccgagcgta gtttatggag cgtcagcgtg
    10321 atcccaccgc cgcagggcag aacgatgtca aaccacggcg aaccttcgcc atagcgaatt
    10381 tcgcgatcgc ggcctgagcc catcatctcc agcgcttcaa aagcggcagc ggcctccacg
    10441 cagccgccag agacaaaacc gcagtaacga ccatcttcgc gaaccaccat ctgcgccccg
    10501 agcgggcgcg ctgcgccgcc gcgtatctcc accagcgtca ccagcaccgc tcctttaccg
    10561 gacattagcg cctctacggc gaagcgcaga atggtccggt ggtcatcggt gagaaacgcc
    10621 tgctctggct tatgccagtg ttcgtcttta tcaaaaagcg ggtatgacat tgtttctcct
    10681 taaaccacat ccggcagctt atcgagcagc ttatccagag tgatgggata atcccgtacc
    10741 cgaataccgg tggcgttata caccgcgttg gcgatagccg cgctcacgcc gcacaggccc
    10801 agctcaccga cacctttggc cttcatcggg gaggatatgg ggtcggtatc atccaggaaa
    10861 atcacctcct gttttgggat atccgcatgg accggcacct cataccccgc catatcgtga
    10921 ttaacgaagt agcccaaacg gtcatccacc gccagctcct ccatcagtgc cgcgcccatg
    10981 cccatagtca ttgcgccaat gacctggctg cgcgcagttt tcggattcag gatgcgtcct
    11041 gcagcacaca cagcgagcat acgccggacc cgaacttctc ccgtcgcgct atgcacgccg
    11101 acctccacaa aatgcccggc aaaggtcgac tgctggtact ctttgctcag tgttccgaat
    11161 tcaatgctct cttccgctgt cagtctgccg cctgcggtgg cttcatgtag cgtggcgctt
    11221 cgggtaccgt tggtaatctt gccgtcggca aactgcgact gctcaggatc aaacccgact
    11281 gccgaggcaa tcatttcgcg aagcttcata caggcggcgt aaacgccgga ggtggaggta
    11341 ttcgcgcccc attgtcctcc agaacccgca gaaaccggga aactggaatc gccgaggtga
    11401 accgcaacct gctccagcgg tacgccaagc atttccgctg ccgtctgggc cagaatggtg
    11461 tagctgccgg tgccaatgtc ggtcatgtcc gtttctacgg taacggtgcc gttttgttcg
    11521 aggtgaaccc gagcacccga tttttccagc agattattgc gaaagcccgc cgcaacaccg
    11581 tggccgacta gccactcccc gtcgcgcacc tgtccgggtg tggcgttgcg ctgcttccag
    11641 ccaaatttat ccgctccggt gcgcaagcac tcgataagct gacggcgaga gaagcagcgc
    11701 gtcgggtcgg cggggtcaac ctgagtgtca ttcaggatgc gaaactcgac gggatcgatg
    11761 cccgcttttt ccgccagttc gtcgatcgcg atttcgagcg ccatcagacc gggggcttcg
    11821 ccgggcgcac gcatggcgtt cccttccggc aaatcaagcg tggcgagccg caggccggta
    11881 tgacgattcg ccccggcgta gagtaattcg ctttgctgta ccgccgtttc cggcgtgccg
    11941 ccgggcaggt ttccagacca gctttcatgt gagatagcgg tgattttccc gctctggtcg
    12001 gcaccgatac gcaagtgctg aaggg
//
LOCUS       DAZUDJ010000441        10565 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.guided.121, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000441 DAZUDJ010000000
VERSION     DAZUDJ010000441.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10565
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.guided.121"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(204..1181)
                     /gene="epmA"
                     /locus_tag="ACHY1N_005656"
     CDS             complement(204..1181)
                     /gene="epmA"
                     /locus_tag="ACHY1N_005656"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HFS4047720.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            1506..3314
                     /gene="frdA"
                     /locus_tag="ACHY1N_005657"
     CDS             1506..3314
                     /gene="frdA"
                     /locus_tag="ACHY1N_005657"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HFS4047721.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGVVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            3307..4041
                     /gene="frdB"
                     /locus_tag="ACHY1N_005658"
     CDS             3307..4041
                     /gene="frdB"
                     /locus_tag="ACHY1N_005658"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HFS4047722.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            4052..4447
                     /gene="frdC"
                     /locus_tag="ACHY1N_005659"
     CDS             4052..4447
                     /gene="frdC"
                     /locus_tag="ACHY1N_005659"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HFS4047723.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            4458..4817
                     /gene="frdD"
                     /locus_tag="ACHY1N_005660"
     CDS             4458..4817
                     /gene="frdD"
                     /locus_tag="ACHY1N_005660"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HFS4047724.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGIVTI"
     gene            4880..6013
                     /locus_tag="ACHY1N_005661"
     CDS             4880..6013
                     /locus_tag="ACHY1N_005661"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HFS4047725.1"
                     /translation="MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAETYGVKSTIEDMACWVRSNMNPRDINDKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSGNKIALAAHPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ"
     gene            6102..6635
                     /gene="blc"
                     /locus_tag="ACHY1N_005662"
     CDS             6102..6635
                     /gene="blc"
                     /locus_tag="ACHY1N_005662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HFS4047726.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDRGMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(6632..6949)
                     /gene="sugE"
                     /locus_tag="ACHY1N_005663"
     CDS             complement(6632..6949)
                     /gene="sugE"
                     /locus_tag="ACHY1N_005663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HFS4047727.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(7131..7277)
                     /gene="ecnB"
                     /locus_tag="ACHY1N_005664"
     CDS             complement(7131..7277)
                     /gene="ecnB"
                     /locus_tag="ACHY1N_005664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HFS4047728.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            complement(7388..7513)
                     /gene="ecnA"
                     /locus_tag="ACHY1N_005665"
     CDS             complement(7388..7513)
                     /gene="ecnA"
                     /locus_tag="ACHY1N_005665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HFS4047729.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            complement(7565..8131)
                     /gene="efp"
                     /locus_tag="ACHY1N_005666"
     CDS             complement(7565..8131)
                     /gene="efp"
                     /locus_tag="ACHY1N_005666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFS4047730.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            8173..9201
                     /gene="epmB"
                     /locus_tag="ACHY1N_005667"
     CDS             8173..9201
                     /gene="epmB"
                     /locus_tag="ACHY1N_005667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0072581 - protein-N6-(L-lysyl)-L-lysine
                     modification to protein-N6-(beta-lysyl)-L-lysine [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HFS4047731.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPDDPLLRQVLTSQDEFVVASGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTVLEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITEALVERFARSTL
                     QILLVNHINHANEVDETFRQAMAKLRRVGVTLLNQSVLLRGVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
     gene            9591..10460
                     /locus_tag="ACHY1N_005668"
     CDS             9591..10460
                     /locus_tag="ACHY1N_005668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HFS4047732.1"
                     /translation="MAISIKGVNTGVIRKSNNFIALALKIKEPRNKESLFFMSVMELR
                     DLLIALESRMHQKHKLDAAARLQYEQARDKVIKKMAENIPEILVDELKNADINRRVNT
                     LELTDNQGENLTFVLTLHDGSKCELVVNELQIEMLARAIIHAINNAEMRELALRITSL
                     LDFLPLYDVDCQENGNLEYDTYSQPEWKHNLFDHYLAVLYRFKDESGKEQFSGAVVKT
                     REATPGKEIEAITRRMLDFSPRLKKLAGVPCQVYVRTVAANNAQPLTQDQCLRALHHL
                     RVQSTSKTAPQAK"
BASE COUNT         2710 a         2682 c         2683 g         2490 t
ORIGIN      
        1 ttcagcgcgt gtataacacg tgcccactga actgcactgc gcaacattga gcaggcagcg
       61 taaaaaccaa tacagaattg atacctggat gatatcaaat atccagtctt aaattgtggc
      121 ctttaacgga aaaatgaaaa catatgctac agaatggcgc ttatcacgcc attcttcgct
      181 gttaattcag taatttttca gaattatgcc cggtcaacgc taaaggcgat gacttcagcc
      241 agtgtctccg cgcccagcgc caacatcacc agacgatcaa cacctaatgc cacgccggaa
      301 cagtcaggca taccgacttt caaggcttca atcagattct ggtcaatggg gtgctgcggc
      361 aaaccgcgcg ccgcgcgctt acggttatct tgttcaaagc gttgttgctg ctcacgggca
      421 tccgtcaatt catggaaacc attcgccagc tcaatacctt tataataaac ctcaaagcgt
      481 tcagcgaccc gatgatcttc ggtactgatt tgcgccagtg atgcctggct ggctggaaag
      541 tggtacacaa aggtcggttt ttctttgcca atatttggct ctacgccaaa ggtaaacagc
      601 aattgtagca gcgtgtcgcg gtcttcttcg gtatcagcaa cattgctcaa atccagtttc
      661 gctgcgactt cccgcagttg cgttttgtcg gcagagagcg ggtcaatttc cagataacgc
      721 aagaaagctt gttgataaga aaggctttct gctgccgggc agtccagcac ctgttgtaag
      781 agatcgtcca cctcgttcat caaccggtac atatcatagt gcggtcgata ccactccagc
      841 atagtgaact cagggttgtg ataacgcccc atctcttcat tacggaagct gcggcacagc
      901 tggaataccg gcccacaacc ggcaaccagc aggcgtttca tatggtattc cgggctggtc
      961 attaaccaga gattcatccc ctgcgaatgc ccggggccaa cgaaacgtgt ctcaaacggg
     1021 accaaatgaa tatcggttac cgtcgcctgg ctcatacaag gcgtctccac ctccagcact
     1081 ccacgatcgg caaagaaacg acggatctcc gccataatcg ccgcgcgttt taataagtta
     1141 ggaatggatg cgctcggctg ccaggatgcc gtttcgctca tagttaaatc tccagttttt
     1201 gacaagggca cgaagtctac tcgcaacgcg acggcgagac aaattttacg caggaatcaa
     1261 acagcggtgg gcagtgacta aaaaaagcac gatctgatgg tttagtaatt aaattaatca
     1321 tcttcagtga taatttagcc ctcttgcgca ctaaaaaaat cgatctcgtc aaatttcaga
     1381 cttatccatc agactatact gttgtaccta taaaggagca gtggaatagc gttcgcagac
     1441 cgtaactttc aggcacttac cctgaagtac ggggctgtgg gataaaaaca atctggagga
     1501 atgtcgtgca aacctttcaa gccgatcttg ccattgtagg cgccggtggc gcgggattac
     1561 gtgctgcaat tgctgccgcg caggcaaatc caaatgcaaa aatcgcacta atctcaaaag
     1621 tatacccgat gcgtagccat accgttgctg cagaaggggg ctccgccgct gtcgcgcagg
     1681 atcatgacag cttcgaatat cactttcacg atacagtagc gggtggcgac tggttgtgtg
     1741 agcaggatgt cgtggattat ttcgtccacc actgcccaac cgaaatgacc caactggaac
     1801 tgtgggggtg cccatggagc cgtcgcccgg atggtagcgt caacgtacgt cgcttcggcg
     1861 gcatgaaaat cgagcgcacc tggttcgccg ccgataagac cggcttccat atgctgcaca
     1921 cgctgttcca gacctctctg caattcccgc agatccagcg ttttgacgaa catttcgtgc
     1981 tggatattct ggttgatgat ggtcatgttc gcggcgtggt agcaatgaac atgatggaag
     2041 gcacgctggt gcagatccgt gctaacgcgg tcgttatggc tactggcggt gcgggtcgcg
     2101 tttatcgtta caacaccaac ggcggcatcg ttaccggtga cggtatgggt atggcgctaa
     2161 gccacggcgt tccgctgcgt gacatggaat tcgttcagta tcacccaacc ggtctgccag
     2221 gttccggtat cctgatgacc gaaggctgcc gcggtgaagg cggtattctg gtcaacaaaa
     2281 atggctaccg ttatctgcaa gattacggca tgggcccgga aactccgctg ggcgagccga
     2341 aaaacaaata tatggaactg ggtccacgcg acaaagtttc tcaggccttc tggcacgaat
     2401 ggcgtaaagg caacaccatc tccacgccgc gtggcgatgt ggtttatctc gacttgcgtc
     2461 acctcggcga gaaaaaactg catgaacgtc tgccgttcat ctgcgaactg gcgaaagcgt
     2521 acgttggcgt cgatccggtt aaagaaccga ttccggtacg tccgaccgca cactacacca
     2581 tgggcggtat cgaaaccgat cagaactgtg aaacccgcat taaaggtctg ttcgccgtgg
     2641 gtgaatgttc ctctgttggt ctgcacggtg caaaccgtct gggttctaac tccctggcgg
     2701 aactggtggt cttcggccgt ctggccggtg aacaagcgac agagcgtgca gcaactgccg
     2761 gtaatggcaa cgaagcggca attgaagcgc aggcagctgg cgttgaacaa cgtctgaaag
     2821 atctggttaa ccaggatggc ggcgaaaact gggcgaagat ccgcgacgaa atgggcctgg
     2881 caatggaaga aggttgcggt atctaccgta cgccggaact gatgcagaaa accatcgaca
     2941 agctggcaga gctgcaggaa cgcttcaagc gcgtgcgcat caccgacacc tccagcgtgt
     3001 tcaacaccga cctgctctac accattgaac tgggccacgg tctgaacgtt gctgaatgta
     3061 tggcgcactc cgcaatggca cgtaaagagt cccgcggcgc acaccagcgt ctggacgaag
     3121 gttgcaccga gcgtgacgac gtcaacttcc tcaaacacac cctcgccttc cgcgatgctg
     3181 atggcacgac tcgcctggag tacagcgacg tgaagattac tacgctgccg ccagctaaac
     3241 gcgtttacgg tggcgaagcg gatgcagccg ataaggcgga agcagccaat aagaaggaga
     3301 aggcgaatgg ctgagatgaa aaacctgaaa attgaggtgg tgcgctataa cccggaagtc
     3361 gataccgcac cgcatagcgc attctatgaa gtgccttatg acgcaactac ctcattactg
     3421 gatgcgctgg gctacatcaa agacaacctg gcaccggacc tgagttaccg ctggtcctgc
     3481 cgtatggcga tttgtggttc ctgcggcatg atggttaaca acgtgccaaa actggcatgt
     3541 aaaaccttcc tgcgtgatta caccgacggt atgaaggttg aagcgttagc taacttcccg
     3601 attgaacgcg atctggtggt cgatatgacc cacttcatcg aaagtctgga agcgatcaaa
     3661 ccgtacatca tcggcaactc ccgcaccgcg gatcagggta ctaacatcca gaccccggcg
     3721 cagatggcaa agtatcacca gttctccggt tgcatcaact gtggtctgtg ctacgccgcg
     3781 tgcccgcagt ttggcctgaa cccagagttc atcggtccgg ctgccattac gctggcgcat
     3841 cgttataacg aagatagccg cgaccacggt aagaaggagc gtatggcgca gttgaacagc
     3901 cagaacggcg tatggagctg tactttcgtg ggctattgct ccgaagtctg cccgaaacac
     3961 gtcgatccgg ctgcggccat tcagcagggc aaagtagaaa gttcgaaaga ctttcttatc
     4021 gcgaccctga aaccacgcta aggagtgcaa catgacgact aaacgtaaac cgtatgtacg
     4081 gccaatgacg tccacctggt ggaaaaaatt gccgttttat cgcttttaca tgctgcgcga
     4141 aggcacggcg gttccggctg tgtggttcag cattgaactg attttcgggc tgtttgccct
     4201 gaaaaatggc ccggaagcct gggcgggatt cgtcgacttt ttacaaaacc cggttatcgt
     4261 gatcattaac ctgatcactc tggcggcagc tctgctgcac accaaaacct ggtttgaact
     4321 ggcaccgaaa gcggccaata tcattgtaaa agacgaaaaa atgggaccag agccaattat
     4381 caaaagtctc tgggcggtaa ctgtggttgc caccatcgta atcctgtttg ttgccctgta
     4441 ctggtaagga gcctgagatg attaatccaa atccaaagcg ttctgacgaa ccggtattct
     4501 ggggcctctt cggggccggt ggtatgtgga gcgcaattat tgcgccggtg atgatcctgc
     4561 tggtgggtat tctgctgcca ctggggctgt ttccgggtga tgcgctgagc tacgagcgcg
     4621 ttctggcgtt cgcgcagagc ttcattggtc gcgtattcct gttcctgatg atcgttctgc
     4681 cgctgtggtg tggtttacac cgtatgcacc acgcgatgca cgatctgaaa attcacgtgc
     4741 ctgcgggcaa atgggttttc tacggtctgg ctgctatcct gacagttgtc acgctgattg
     4801 gtatcgttac aatctaacgt atcgccaatg taaatccggc ccgcctatgg cgggccgttt
     4861 tgtatggaaa ccagacctta tgttcaaaac gacgctctgc gccttattaa ttaccgcctc
     4921 ttgctccaca tttgctgccc ctcaacaaat caacgatatt gtgcatcgca caattacccc
     4981 gcttatagag caacaaaaga tccccggtat ggcggtggcg gtaatttatc agggtaaacc
     5041 ttattacttt acctggggct atgcggacat cgccaaaaag cagcccgtca cacagcaaac
     5101 gttgtttgag ttaggttcgg tcagcaaaac atttacgggc gtgcttggtg gcgacgctat
     5161 tgctcgaggg gaaatcaagt taagcgatcc cacaacaaaa tactggcctg aacttaccgc
     5221 taaacagtgg aatgggatca cactattaca tctcgcaacc tacactgctg gcggcctgcc
     5281 attgcaggtg ccggatgagg tgaaatcctc aagcgacttg ctgcgcttct atcaaaactg
     5341 gcagcctgca tgggcgccag gaacacaacg tctgtatgcc aactccagta tcggtttgtt
     5401 cggcgcactg gctgtgaagc cgtctggttt gagttttgag caggcgatgc aaacacgtgt
     5461 cttccagcca ctcaaactca accatacgtg gattaatgta ccgcccgcag aagaaaagaa
     5521 ttacgcctgg ggatatcgcg aaggcaaggc agttcatgtt tcgccagggg cgttagatgc
     5581 tgaaacttat ggtgtgaagt cgaccattga agatatggcc tgctgggtac gaagcaatat
     5641 gaatccccgt gatatcaacg acaaaacact tcagcaaggg atacaactgg cacaatctcg
     5701 ctactggcaa accggcgata tgtatcaggg cctgggctgg gaaatgctgg actggccggt
     5761 aaatcctgac agcatcatta acggcagtgg caataaaatt gcactggcag cacaccccgt
     5821 aaaagcgatt acgcccccaa ctcctgcagt acgcgcatca tgggtacata aaacaggggc
     5881 aaccggcgga tttggtagct atgtcgcgtt tattccagaa aaagagctgg gtatagtgat
     5941 gctggctaac aaaaactatc ccaatccagc gagagtcgcc gccgcctggc agattctcaa
     6001 cgctctacag taaaatttca tcgggtccga attttcggac cttttctgcg cttttccttg
     6061 ctgtcatcta cacttagaaa aaaaccagta aggaaacatt tatgcgcctg ctccctctcg
     6121 ttgccgcagc gacagctgca tttctggtcg ttgcctgcag ttctcctacg ccgccgcgtg
     6181 gcgtaacagt agtgaataat ttcgacgcca aacgttatct cggtacctgg tatgagattg
     6241 cccgttttga tcaccgtttt gaacgtggac tggaaaaagt caccgcaaca tacagcctgc
     6301 gtgatgacgg cggcctgaat gtcattaata aaggctataa ccctgacaga ggaatgtggc
     6361 agcagagtga agggaaagcg tactttaccg gcgcaccaac tcgcgctgcg ctgaaagtgt
     6421 cattctttgg tcctttctat ggcggttata acgttattgc actcgatcgg gaataccgcc
     6481 atgcgctggt ttgcggcccg gaccgcgact acctgtggat actctcccgc acgccaacca
     6541 tttctgacga agtgaaacag gagatgctgg cagtcgcgac ccgggaaggg tttgatgtca
     6601 gtaagtttat ttgggtacag cagcccggta gttagtgagt gctgagtttc agaccaataa
     6661 tccccaatac gattaacgcc agactcgcca ggcgcatcgg gttagcggac tcaccgagca
     6721 gcacaatgcc ggtgatagcc gcgccgactg cgccaatacc cgtccacacg gcataagccg
     6781 tccctactgg taacgatttc atcgcccagg caagtagcgc catactgaca atcatcgccg
     6841 tcacggtaat aacactcggc gtcaaacgac taaagccgtg ggtatatttc aggccaacgg
     6901 cccataccac ttccagcaga ccagcaataa ctaagataat ccaggacata tcaggctccg
     6961 gagaattggg gccgtccccg gtgaaaagag gcgtttgcag gtcgtcctgc aaagctgatg
     7021 gttgaacgga tattttgcca ggtggcaggg gaatttcaac tattacctta gtgactatcg
     7081 cagaaaaaac aaacggcacg acatacctgt cgtaccgtta ttgcttattg ctattgctgc
     7141 gctttcgttg ctgcgccaga aatcgcgtta ccgccatcag aaatgtcttc accaacgcca
     7201 cgcgtggtgt tgcaggcagt taatactgtt gaaagcacca gaacagaaaa gatcgctgca
     7261 attgtcttct tcaccataac gtcttccttt taggtaatgt tatttatgtt tgcctatagc
     7321 aaattaataa tagacaacat cgccaaaaat gacggaaatc tgatgatttt tcggaagaga
     7381 agaaaaatta gctggcagcg cgagagatgg agttgccgag atgtttgatg tcttcgccga
     7441 aaccgcgagc ggtgttacag cccgtgagca gcgtgctggc aagcaaaaca agaacgataa
     7501 ggcgtttcat catctctgac ctgaataagt gatggtgcag cctgcaggcc gcaccacaac
     7561 cgcattactt cacgcgagag acgtattcac cagagcgggt atccactttg atgacttcgc
     7621 cgatttgtac gaacagcgga accttaacca cagcgccagt agacagggta gccggtttgc
     7681 cgccagtacc tgcggtatca cctttcaggc ccggatcggt atcaacgatt tccagttcaa
     7741 cgaagttcgg cggagtaacg gagatcggct gaccattcca cagagttacg atacactctg
     7801 cctgatccag cagccattta gcgttgtcgc caattgcttt tgcatcagca gacagctgct
     7861 cgaaagtttc gttgttcatg aagtgccaga actcaccgtc gttgtacagg taagtcaggt
     7921 tcatatcgac aacatcagcg ccttcagcgg aatcagtaga tttgaaggtt ttttctacgc
     7981 gagtaccggt cagcagacga cgcagtttaa cgcgagcaaa tgcctggcct ttacccggtt
     8041 ttacgaattc actcgcttca accgcgtaag gttcgccgtc taacatgatt ttaagaccag
     8101 cacgaaaatc gttgctatag tacgttgcca taaggccctc tgaaatttgt taattggtag
     8161 ctaagccaca aaatggcgca tattgtaacc ctaaataccc catccagaga agattggtta
     8221 acgcaacttg ccgatgttgt gaccgatcct gatgaacttc tgcgtctttt gaatatagac
     8281 gcggacgaaa aactgttggc cggacgcagc gccaaaaagc tgtttgccct gcgtgtgccc
     8341 cgctcattta tcgatcgcat ggagaaaggc aatccggacg atcctctttt gcgtcaggta
     8401 cttacctcgc aagatgagtt tgtcgtcgcg tccggattct ccaccgaccc gctggaagaa
     8461 cagcacagcg tagtgcctgg tttgttgcat aaataccaca accgggcgct tttgctggtc
     8521 aaaggcggct gcgcggtaaa ttgccgctat tgcttccgtc gccacttccc ctatgccgaa
     8581 aatcagggca acaagcgtaa ctggcagact gttcttgagt atgttgctgc gcatccggaa
     8641 ctggacgaga tgattttctc cggcggcgat ccgctgatgg cgaaagatca cgagctggac
     8701 tggttgctca cacaactgga agccatcccg catatcaaac gtctgcggat tcacagccgt
     8761 ctgccgattg tgatcccggc acgtatcacc gaggcgctgg ttgaacgctt tgcccgttct
     8821 acgctgcaaa tcttgctggt gaatcacatc aatcatgcca atgaggtaga tgaaacgttc
     8881 cgtcaggcga tggctaaatt gcgccgtgtc ggtgtcaccc tgcttaacca gagcgttctg
     8941 ttacgtggtg tgaacgataa cgcacaaacg ctggcaaacc tgagtaatgc gttgttcgat
     9001 gccggcgtaa tgccgtatta cctgcatgtg ctcgataaag tacagggcgc ggcgcatttt
     9061 atggtgagtg atgacgaagc acggcagatt atgcgtgagt tgctgacact ggtgtcgggt
     9121 tatctggtgc cgaaactggc gcgagaaatc ggcggcgaac ccagcaaaac gccgctggat
     9181 ctccagctac gccagcagta actgattaaa cagggaagtt aaacattagc ctgatgcgct
     9241 acgcttatca ggcctacatt gtgcattgaa attgaatgga tttgcaatga actgtaggcc
     9301 ggataaggcg tttacgccgc atccggcaag agcaacaaac gcaagtacag caacctgtca
     9361 ttaaactggg aaatttaatc tttgcacgtt gcataacctt taattattca tatgcattgc
     9421 tgttgttact ttttatatag ctaacaccaa taattaacct ttcttttctg tttatataga
     9481 gtgagcacgg ctatttatgt tattttaaca actattacta ccaagcccat ttatctggct
     9541 tataaattaa aattaattat ttaattgaga aatggttagg gagaacctac atggccataa
     9601 gcatcaaggg tgttaatacc ggtgttattc gcaagagtaa taatttcatt gcactggcgc
     9661 tgaaaattaa agaacctcgc aataaagaat cgttgttctt tatgtctgtc atggaactgc
     9721 gcgacctgct gattgcgctg gaaagtcgta tgcatcaaaa gcataaactg gatgctgctg
     9781 cacgccttca gtatgagcaa gctcgcgata aagtcattaa aaaaatggca gaaaacatcc
     9841 cagaaattct ggttgatgag cttaaaaatg ccgatattaa tcgtcgggtt aacacgctgg
     9901 aacttaccga taatcaaggc gaaaatctta ccttcgtatt aacgctacat gacggtagca
     9961 aatgtgagtt agtcgtcaat gagttgcaga ttgaaatgct ggcgcgagca atcattcatg
    10021 caattaataa tgcggaaatg cgtgaactgg cattacgtat tacctcactg ttagatttcc
    10081 tgccgttata tgacgttgac tgccaggaaa atggcaatct ggaatatgac acctattccc
    10141 aaccggaatg gaaacataac ctgttcgacc attatctggc ggtgctttac cgctttaaag
    10201 atgaaagtgg caaagaacaa tttagcggcg cagtggtgaa aacgcgtgaa gcaacgccgg
    10261 gtaaagaaat agaggcgatc actcgccgaa tgcttgattt cagcccacga ctgaaaaaac
    10321 tcgcgggtgt gccatgtcag gtctatgttc gcaccgtagc ggcgaataac gcccaaccgc
    10381 taacccagga tcaatgctta cgcgcgctgc atcacttacg tgttcaatcc accagcaaaa
    10441 ctgcaccaca ggcgaaataa tctcatcttt gctaatgcga ggctggagcc atccagcctg
    10501 aaatgactga taacgtgatc gttggtcatg ccggatgcgg cgtaaacgcc ttatccggcc
    10561 tacaa
//
LOCUS       DAZUDJ010000442         5413 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.guided.157, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000442 DAZUDJ010000000
VERSION     DAZUDJ010000442.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5413
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.guided.157"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            complement(48..296)
                     /locus_tag="ACHY1N_005669"
     CDS             complement(48..296)
                     /locus_tag="ACHY1N_005669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemagglutinin"
                     /protein_id="HFS4047733.1"
                     /translation="MGAYLGSKVKGEDPTVPMVGNAIGTVLGNKAGEKFTKEMLSKGY
                     SPVTSDVIGTVSGGTMTIGTAIDFGIEESQKKGDSNEK"
     gene            660..854
                     /locus_tag="ACHY1N_005670"
     CDS             660..854
                     /locus_tag="ACHY1N_005670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-zinc-cadmium resistance protein"
                     /protein_id="HFS4047734.1"
                     /translation="MVFVATQHGQKVEFTPQPVKLGQSSGDSQWIEVVNGLNQGQKYA
                     AQGSFLLKSEMEKGEASHEH"
     gene            844..1680
                     /locus_tag="ACHY1N_005671"
     CDS             844..1680
                     /locus_tag="ACHY1N_005671"
                     /inference="COORDINATES: protein motif:HMM:NF013069.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HFS4047735.1"
                     /translation="MSTKSPHIPDHESVKPEGLFDRLIQFSIHNAIWVMLFVAAWIAI
                     GIYSYQKLPIDAVPDITNTQVQINTSANGFTALEMEQRITYPIENAMSGMPKMEQTRS
                     ISRYGLSQVTIIFEDGTDIYWARQLINQRLQEAMGEMPEDVQPNMSPISTGLGEIYQW
                     VIKAEPNAKKPDGTPYSAMDLREIQDWIVRPQLQRVKGVAEINSIGGFNKTYVVAPDL
                     NRLQQLQIPLSDLQTALTENNENRGAGYIEKNGQQLTVRVPHSIVNKTFLSFIFNGLF
                     SC"
     gene            1921..2736
                     /gene="sul2"
                     /locus_tag="ACHY1N_005672"
     CDS             1921..2736
                     /gene="sul2"
                     /locus_tag="ACHY1N_005672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /protein_id="HFS4047736.1"
                     /translation="MNKSLIIFGIVNITSDSFSDGGRYLAPDAAIAQARKLMAEGADV
                     IDLGPASSNPDAAPVSSDTEIARIAPVLDALKADGIPVSLDSYQPATQAYALSRGVAY
                     LNDIRGFPDAAFYPQLAKSSAKLVVMHSVQDGQADRREAPAGDIMDHIAAFFDARIAA
                     LTGAGIKRNRLVLDPGMGFFLGAAPETSLSVLARFDELRLRFDLPVLLSVSRKSFLRA
                     LTGRGPGDVGAATLAAELAAAAGGADFIRTHEPRPLRDGLAVLAALKETARIR"
     gene            2823..3125
                     /locus_tag="ACHY1N_005673"
     CDS             2823..3125
                     /locus_tag="ACHY1N_005673"
                     /inference="COORDINATES: protein motif:HMM:NF014877.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4047737.1"
                     /translation="MVRKYFGTDGIRGKANEGAMTAETALRVGMAAGRVFRRGDHRHR
                     VVIGKDTRLSGYMLEPALTAGFTSMGMDVFLFGPLPTTYRKNKRPFHPSPTALDRS"
     gene            complement(3509..4345)
                     /locus_tag="ACHY1N_005674"
     CDS             complement(3509..4345)
                     /locus_tag="ACHY1N_005674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="HFS4047738.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLK
                     PIEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATE
                     IAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMM
                     SNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDP
                     RRIAQMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQT
                     SY"
     gene            complement(4345..5148)
                     /locus_tag="ACHY1N_005675"
                     /note="aph(3'')-Ib"
     CDS             complement(4345..5148)
                     /locus_tag="ACHY1N_005675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3'')-Ib"
                     /protein_id="HFS4047739.1"
                     /translation="MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASR
                     RGELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAW
                     PSMGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLL
                     ARVERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLA
                     LMIANAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
BASE COUNT         1305 a         1453 c         1356 g         1299 t
ORIGIN      
        1 atatacacct tgaaaaaaga tagaataaca gccataagtc aggagattta tttttcatta
       61 ctatctcctt tcttctgaga ttcttcaatg ccgaagtcga tagctgtacc tatagtcata
      121 gtccccccag agacagttcc aataacatca gaagttactg gcgagtatcc cttcgatagc
      181 atttctttgg tgaatttctc tccggctttg ttacccagaa cagtacctat tgcattcccc
      241 accattggca ctgtagggtc ttcgccttta actttacttc ctaagtaagc tcccattgtg
      301 ttaataaatg tgctgaaaat gacactttta ccctgtgtaa gcccaccttc acctgcggca
      361 ataagagtat ccgtagcact atatttctca cccggcttaa gggttaaata ctgcttaatg
      421 ccatctgtta cacctcctaa aaggctaccc ccaataacag caacggtacc cgcggctggg
      481 actataagtt cgccaccaag aacagaagca cctgctcccc atgcaatcag taaacctctg
      541 acaggatcct gtccttccgg aagattacct gttgcaagtt tatcagaagc atacttaatt
      601 gtgaaagtac cgcattacgg gtacttaagt ccgcagttca gaatgtcgat ggaaaagatg
      661 tggtttttgt cgccactcag catggacaaa aagttgaatt cactccgcag ccggtgaaat
      721 taggtcaatc gtctggggat agccagtgga ttgaagtggt aaatgggctt aatcagggac
      781 aaaaatatgc cgctcaaggc agtttcttac tgaaatctga gatggaaaaa ggagaggctt
      841 cacatgagca ctaaaagccc tcacattcca gaccacgaat cggtaaaacc tgaagggctg
      901 tttgatcggc tgatccagtt ttctattcat aacgcaatct gggtcatgct gtttgttgca
      961 gcctggattg ctattggtat ttatagttat caaaagttac cgattgatgc tgtaccggat
     1021 attaccaata ctcaggtgca gattaacact tcagccaatg gctttacggc tttggaaatg
     1081 gaacagcgga ttacctatcc aattgagaat gccatgtcag gcatgccgaa aatggaacaa
     1141 acccgttcga tttcacgcta cggcttatcg caagtgacca tcatttttga agatggcacg
     1201 gatatttact gggccagaca gcttatcaac cagcgcttgc aagaagcaat gggagaaatg
     1261 cctgaagatg tgcaacctaa catgtcgcct atttcgacag gtttaggtga aatctatcaa
     1321 tgggtgatta aagccgaacc aaatgctaaa aagccggatg gaacccctta ttcggcgatg
     1381 gatttacgtg aaattcagga ttggattgta agaccgcaat tacagcgcgt aaaaggcgtt
     1441 gcggagatca acagtatcgg tggctttaat aaaacctatg tggttgcccc tgatctgaac
     1501 cgattgcaac aattgcaaat tcctttgtct gatttacaaa ctgccttaac agagaataat
     1561 gaaaaccgtg gtgctggcta tattgagaaa aatggacaac agctaacggt tcgtgttccc
     1621 cactctattg taaacaagac atttttatct tttatattca atggcttatt ttcctgctaa
     1681 ttggtaatac catgaaaaat accatgctca gaaaaggctt aacaatattt tgaaaaattg
     1741 cctactgagc gctgccgcac agctccatag gccgctttcc tggctttgct tccagatgta
     1801 tgctattctg ctcctgcagc taatggatca ccgcaaacag gttactcgcc tggggattcc
     1861 ctttcgaccc gagcatccgt atgagactca tgctcgatta ttattattat agaagccccc
     1921 atgaataaat cgctcatcat tttcggcatc gtcaacataa cctcggacag tttctccgat
     1981 ggaggccggt atctggcgcc agacgcagcc attgcgcagg cgcgtaagct gatggccgag
     2041 ggggcagatg tgatcgacct cggtccggca tccagcaatc ccgacgccgc gcctgtttcg
     2101 tccgacacag aaatcgcgcg tatcgcgccg gtgctggacg cgctcaaggc agatggcatt
     2161 cccgtctcgc tcgacagtta tcaacccgcg acgcaagcct atgccttgtc gcgtggtgtg
     2221 gcctatctca atgatattcg cggttttcca gacgctgcgt tctatccgca attggcgaaa
     2281 tcatctgcca aactcgtcgt tatgcattcg gtgcaagacg ggcaggcaga tcggcgcgag
     2341 gcacccgctg gcgacatcat ggatcacatt gcggcgttct ttgacgcgcg catcgcggcg
     2401 ctgacgggtg ccggtatcaa acgcaaccgc cttgtccttg atcccggcat ggggtttttt
     2461 ctgggggctg ctcccgaaac ctcgctctcg gtgctggcgc ggttcgatga attgcggctg
     2521 cgcttcgatt tgccggtgct tctgtctgtt tcgcgcaaat cctttctgcg cgcgctcaca
     2581 ggccgtggtc cgggggatgt cggggccgcg acactcgctg cagagcttgc cgccgccgca
     2641 ggtggagctg acttcatccg cacacacgag ccgcgcccct tgcgcgacgg gctggcggta
     2701 ttggcggcgc tgaaagaaac cgcaagaatt cgttaactgc acattcggga tatttctcta
     2761 tattcgcggt tcagcaggca tgtccccttt gagggcgacc cgacgacagg ataatcgacc
     2821 ttatggtgcg caaatatttc ggcacagacg gtattcgtgg caaagccaac gaaggcgcga
     2881 tgacggcgga aaccgccttg cgcgtcggca tggcggctgg ccgtgtcttt cgtcgcggtg
     2941 accaccgcca tcgtgtcgtg atcggcaagg atacgcgcct gtcgggctat atgcttgaac
     3001 ccgcgctcac agccggtttc acctcgatgg gcatggacgt attccttttt ggcccgctgc
     3061 cgacaacgta taggaagaat aaacgccctt ttcacccaag tccaacagct ttggaccgca
     3121 gttgactctt tcgacacccc tgcgatgcaa cccaatccgg ctgacgggga gccagcaacg
     3181 ctgaaaattt accctcctct ttcccactag cggctccttt tccgacaacc agcacggcgg
     3241 atccctgccg cggcgctgtg aacgcagcat tttgattggt atcgttggcc ttcaggctcg
     3301 tcagtcaaac agacccagga gcagctcagc cggtggcgcc cggctttcgg gtaacgccct
     3361 ggtcccgctg gtttcggctt tgtgcttcag gtgatcaagg atggggtcgt ttgcgggaga
     3421 gggcgaaatc ctacgctaag gctttggcca acgatattct ccggtaagat tgatgtgttc
     3481 ccaggggata ggagaagtcg cttgatatct agtatgacgt ctgtcgcacc tgcttgatcg
     3541 cggccgcgat agctagatcg cgttgctcct cttctccatc cgcgttccaa gctgcggaaa
     3601 ggcacccata agcgtacgcc tggtcgagca ggcgacgcgg atcgacgtcc agcgcacgag
     3661 agaatgcgtc cgccatctgt gcaatgcgtc taggatcgag acaaaggtcg tctctgtcag
     3721 ccggatcgta gaacatattg gcggcgccaa agcccacttc accgaccaga ccgacgggat
     3781 ctatcaccag ccagccgcga ctggagaaca tgatgttttc atgatgcaga tcgccatgta
     3841 gcccacgcag ttccgaggca ttgctcatca tttgatcggc tataatcgcc gcgtggacgt
     3901 agtcagtttg acaacctgcg ttttgatcat cgcgcgcccg ctgaaacaaa gctgcaaagc
     3961 gatcccggat cgggagaagg gcagaaggca ggggttcctc agatgcggca tacagcttcg
     4021 ccattagttc cgctgcaatt tcggtcgcct ggtagtcgcc gtgctcggca acgatgtgag
     4081 agagcattcg ctccccggca tattcgagca acatcagatt gttctcacga ccgagcaacc
     4141 ggactgctcc cctcccattg cgccatacca gatagtcggc cccgcgcagt tcatcagcaa
     4201 tgtcttctat aggtttcaat cccttgacga ttgcaggagt cccgtctggc aatgaaactt
     4261 tccaaacgag gctggaaaag gtgtccgcaa tgagaacagg ttgcgaaacg tgccaatgag
     4321 caggaaaaac aggcggcatg aacatcaacc ccaagtcaga gggtccaatc gcagatagaa
     4381 ggcaaggcgt tcgcggtcgg gggcttcgat ccccaataca ttgaatagga cagcgaaggc
     4441 gcgctctgct tcatctggcg ctgcccagtt ctcttcggcg ttagcaatca tgagtgccaa
     4501 atcggcatag cgatctgctg ttccgagccg cccaaggtcg atcagacccg tgcattgaag
     4561 agttttaggg tccaccatga agttcggcat gcagggatca ccatggcaaa caaccatatc
     4621 ggtgcgctct tggtcgagcc gcaccggtag ctctcgttcg acacgagcca aaagatcgag
     4681 ctgcggcgta ctcttgtcct cgtccggtaa gaagtcggga ttgacggcat tgcgggacac
     4741 cacatcaacg gcgcgtccga acattcgcga cagcctgcgc tcaaacggac attgatcaac
     4801 cgataggctg tgaacagcgc caagttgctg ccccattgac ggccacgctt tgagcaaatc
     4861 cgctccagac agatcagccg ccggtactcc cggaattgcc gttatcacca agcatgcacc
     4921 ctcctgttcc tcctgccagt tgatcacctc ggggcaagcc acacctcgac ctttgagcca
     4981 aatgaggcgg tcacgctctc cagcgagctc accgcggcgg gaagcaggtg cgattttcgc
     5041 gaaggcatgc ccgtcaccac gtcgaaaaac aaaatcacca gattctccgc ctctgacagg
     5101 caaccagtca gaatgcgatt caccaaaaaa aatattagtt cgattcaatg gaggttcctt
     5161 cagttttctg atgaagcgcg gaggtggctc aacctgcgaa aagaaacgag ttgctacgta
     5221 agtccgagaa catgctttcc atggtcttgc accggttgtg ttccggtcta tctctcattt
     5281 taagcggctt ttttctcaaa tgccaccggc gatttccagc cgagtgctga tgaatcccct
     5341 aatgattttt atcaaaatca ttaagttaag gtagatacac atcttgtcat atgatcaaat
     5401 ggtttcgcga aaa
//
LOCUS       DAZUDJ010000443         4034 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.guided.180, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000443 DAZUDJ010000000
VERSION     DAZUDJ010000443.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.guided.180"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            363..683
                     /locus_tag="ACHY1N_005676"
     CDS             363..683
                     /locus_tag="ACHY1N_005676"
                     /EC_number="1.14.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HFS4047740.1"
                     /translation="MIAVIFEVQIQPDQQTRYLTLAEELRPLLSHVAGFISIERFQSL
                     ATEGKMLSLSWWENEYAVLQWKNHVLHAKAQQEGRESIFDFYKISIAHITREYSFKKD
                     KDNV"
     gene            676..1062
                     /locus_tag="ACHY1N_005677"
     CDS             676..1062
                     /locus_tag="ACHY1N_005677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HFS4047741.1"
                     /translation="MFDVHVVLDNQIGQLALLGKTLGNKGIGLEGGGIFTVGDECHAH
                     FLVEQGKEAKIALEQAGLLVLAIRTPLIRKLKHEKPGELGEIARVLAENNINILVQYS
                     DHANQLILITDNDSMAASVTLPWAIK"
     gene            1070..1756
                     /locus_tag="ACHY1N_005678"
     CDS             1070..1756
                     /locus_tag="ACHY1N_005678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFS4047742.1"
                     /translation="MANLIRKEVTFESSIAAIGAAMSDISRVKILSALMDGRAWTATE
                     LSSVANISASTASSHLSKLLDCQLITVVAQGKHRYFRLAGKDIAELMESMMGISLNHG
                     VHAKVSTPVHLRKARTCYDHLAGEVAVKIYDSLCQQQWITENGSMITLSGIQYFHEMG
                     IDVPSKHSRKICCACLDWSERRFHLGGYVGAALFSLYESKGWLTRHLGYREVTITEKG
                     YAAFKTHFHI"
     gene            complement(1734..2357)
                     /gene="tetR(B)"
                     /locus_tag="ACHY1N_005679"
     CDS             complement(1734..2357)
                     /gene="tetR(B)"
                     /locus_tag="ACHY1N_005679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HFS4047743.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            2439..3644
                     /gene="tet(B)"
                     /locus_tag="ACHY1N_005680"
     CDS             2439..3644
                     /gene="tet(B)"
                     /locus_tag="ACHY1N_005680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HFS4047744.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVTFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
     gene            complement(3757..>4034)
                     /locus_tag="ACHY1N_005681"
     CDS             complement(3757..>4034)
                     /locus_tag="ACHY1N_005681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tetracyline resistance-associated
                     transcriptional repressor TetC"
                     /protein_id="HFS4047745.1"
                     /translation="LIPIQEVMPIIGWNELEKISLEYITGKVNAIVSKLIQENQLKAY
                     DDDVLKNLLNGWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK"
BASE COUNT         1156 a          720 c          864 g         1294 t
ORIGIN      
        1 atctttaaca atgagtttta ttagggtatc cataactttt agttaatagg gtcataattt
       61 tagtgtgatc ttaatcatga aatattaaaa agattaaaat aacaacaatg gtatttaatg
      121 atgggtaaac ctaaatacca tgcgggatcc gcactatttt cggtgatagc aaaaaataaa
      181 aaagtataaa taataaacaa aattataaga gaaggagaac atgataagcg caggccgagc
      241 aatttaaaga agtgtgatat acaacataaa acagcagcat gacctttcta tatttcgttg
      301 cttatcgaag tgttaatttt cgggtggatt actctgtttg ttgattaata acggagaaaa
      361 atatgattgc tgtaatattt gaggtgcaaa tacaacccga ccaacaaact cgctatttga
      421 ctttagctga ggagttaaga ccactattaa gtcatgtagc tggttttatt tcaattgaac
      481 gttttcaaag tctagctaca gaaggaaaaa tgttatcgct atcttggtgg gaaaacgaat
      541 acgcagttct gcaatggaaa aatcatgttt tacatgcgaa agctcaacaa gaagggcgag
      601 agtcaatatt tgatttttac aaaattagta ttgctcatat tactcgcgaa tattcattta
      661 aaaaggacaa ggataatgtt tgatgttcac gttgttttag ataatcaaat aggacaatta
      721 gcattactag gaaaaacatt aggtaataaa ggtattggat tggaaggggg agggatattt
      781 acggttggtg atgaatgcca tgctcatttt cttgttgaac aaggaaagga agctaaaata
      841 gcgctagagc aagctggact gttagtactt gcgatccgga caccattaat tcgtaagtta
      901 aaacatgaaa aaccggggga acttggcgaa atagcacgag tattggcgga gaataacatt
      961 aatattttag tgcaatacag tgaccatgct aaccaactga tattaataac ggacaatgat
     1021 agtatggctg catctgttac gctcccttgg gcaataaagt gaacttgcga tggctaattt
     1081 aatacgaaaa gaggttacct ttgagtcctc aatagccgcg ataggggcgg ctatgtctga
     1141 catttcacga gttaaaatac tcagtgcttt gatggatggg cgagcttgga cggccactga
     1201 gctaagttct gtggcgaata tatcagcttc aacggcgagc agtcatttat ctaaattatt
     1261 agattgccag ctaatcacag tagtagctca aggcaagcat cgttattttc ggctagcagg
     1321 aaaagatatt gctgaattga tggaaagtat gatggggatc tccttaaacc atggcgtaca
     1381 tgccaaagtt tccacgccag tgcatttacg aaaagcacgt acttgctatg atcatttagc
     1441 tggcgaagtt gccgttaaga tctatgattc cctttgtcaa cagcaatgga tcactgaaaa
     1501 tggttcaatg atcacattaa gtggtattca atattttcat gaaatgggaa ttgacgttcc
     1561 ttccaaacat tcacgtaaaa tctgttgtgc gtgtttagat tggagtgaac gccgtttcca
     1621 tttaggtggg tacgttggag ccgcattatt ttcgctttat gaatctaaag ggtggttaac
     1681 tcgacatctt ggttaccgtg aagttaccat cacggaaaaa ggttatgctg cttttaagac
     1741 ccactttcac atttaagttg tttttctaat ccgcatatga tcaattcaag gccgaataag
     1801 aaggctggct ctgcaccttg gtgatcaaat aattcgatag cttgtcgtaa taatggcggc
     1861 atactatcag tagtaggtgt ttccctttct tctttagcga cttgatgctc ttgatcttcc
     1921 aatacgcaac ctaaagtaaa atgccccaca gcgctgagtg catataatgc attctctagt
     1981 gaaaaacctt gttggcataa aaaggctaat tgattttcga gagtttcata ctgtttttct
     2041 gtaggccgtg tacctaaatg tacttttgct ccatcgcgat gacttagtaa agcacatcta
     2101 aaacttttag cgttattacg taaaaaatct tgccagcttt ccccttctaa agggcaaaag
     2161 tgagtatggt gcctatctaa catctcaatg gctaaggcgt cgagcaaagc ccgcttattt
     2221 tttacatgcc aatacaatgt aggctgctct acacctagct tctgggcgag tttacgggtt
     2281 gttaaacctt cgattccgac ctcattaagc agctctaatg cgctgttaat cactttactt
     2341 ttatctaatc tagacatcat taattcctaa tttttgttga cactctatca ttgatagagt
     2401 tattttacca ctccctatca gtgatagaga aaagtgaaat gaatagttcg acaaagatcg
     2461 cattggtaat tacgttactc gatgccatgg ggattggcct tatcatgcca gtcttgccaa
     2521 cgttattacg tgaatttatt gcttcggaag atatcgctaa ccactttggc gtattgcttg
     2581 cactttatgc gttaatgcag gttatctttg ctccttggct tggaaaaatg tctgaccgat
     2641 ttggtcggcg cccagtgctg ttgttgtcat taataggcgc atcgctggat tacttattgc
     2701 tggctttttc aagtgcgctt tggatgctgt atttaggccg tttgctttca gggatcacag
     2761 gagctactgg ggctgtcgcg gcatcggtca ttgccgatac cacctcagct tctcaacgcg
     2821 tgaagtggtt cggttggtta ggggcaagtt ttgggcttgg tttaatagcg gggcctatta
     2881 ttggtggttt tgcaggagag atttcaccgc atagtccctt ttttatcgct gcgttgctaa
     2941 atattgtcac tttccttgtg gttatgtttt ggttccgtga aaccaaaaat acacgtgata
     3001 atacagatac cgaagtaggg gttgagacgc aatcgaattc ggtatacatc actttattta
     3061 aaacgatgcc cattttgttg attatttatt tttcagcgca attgataggc caaattcccg
     3121 caacggtgtg ggtgctattt accgaaaatc gttttggatg gaatagcatg atggttggct
     3181 tttcattagc gggtcttggt cttttacact cagtattcca agcctttgtg gcaggaagaa
     3241 tagccactaa atggggcgaa aaaacggcag tactgctcgg atttattgca gatagtagtg
     3301 catttgcctt tttagcgttt atatctgaag gttggttagt tttccctgtt ttaattttat
     3361 tggctggtgg tgggatcgct ttacctgcat tacagggagt gatgtctatc caaacaaaga
     3421 gtcatcagca aggtgcttta cagggattat tggtgagcct taccaatgca accggtgtta
     3481 ttggcccatt actgtttgct gttatttata atcattcact accaatttgg gatggctgga
     3541 tttggattat tggtttagcg ttttactgta ttattatcct gctatcgatg accttcatgt
     3601 taacccctca agctcagggg agtaaacagg agacaagtgc ttagttattt cgtcaccaaa
     3661 tgatgttatt ccgcgaaata taatgaccct cttgataacc caagagggca ttttttacga
     3721 taaagaagat ttagcttcaa ataaaaccta tctattttat ttatctttca agctcaataa
     3781 aaagccgcgg taaatagcaa taaattggcc ttttttatcg gcaagctctt ttaggttttt
     3841 cgcatgtatt gcgatatgca taaaccagcc attgagtaag tttttaagca catcatcatc
     3901 ataagcttta agttggttct cttggatcaa tttgctgaca atggcgttta ccttaccagt
     3961 aatgtattca aggctaattt tttcaagttc attccaacca atgataggca tcacttcttg
     4021 gatagggata aggt
//
LOCUS       DAZUDJ010000444         2985 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Escherichia coli isolate 1812M24648
            SAMN43251771-rid23067983.guided.206, whole genome shotgun sequence.
ACCESSION   DAZUDJ010000444 DAZUDJ010000000
VERSION     DAZUDJ010000444.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN43251771
            Sequence Read Archive: SRR30292866
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-SEP-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002349719.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002349719.1
            Genome Coverage       :: 99x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/22/2024 04:39:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 5,686
            CDSs (total)                      :: 5,608
            Genes (coding)                    :: 5,384
            CDSs (with protein)               :: 5,384
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 224
            CDSs (without protein)            :: 224
            Pseudo Genes (ambiguous residues) :: 0 of 224
            Pseudo Genes (frameshifted)       :: 97 of 224
            Pseudo Genes (incomplete)         :: 122 of 224
            Pseudo Genes (internal stop)      :: 56 of 224
            Pseudo Genes (multiple problems)  :: 43 of 224
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2985
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN43251771-rid23067983.guided.206"
                     /serotype="O103:H 2"
                     /isolate="1812M24648"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66267 N 12.587343 E"
                     /collection_date="2018-12"
                     /collected_by="SSI"
                     /note="subtype: stx1a"
     gene            <1..183
                     /locus_tag="ACHY1N_005682"
     CDS             <1..183
                     /locus_tag="ACHY1N_005682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinG"
                     /protein_id="HFS4047746.1"
                     /translation="KSGNLVPYRVELINRIGQEAVDEIESNHNRHRWTVEECRAIKAK
                     YQQKLKDLRNSRSEAA"
     gene            180..374
                     /locus_tag="ACHY1N_005683"
     CDS             180..374
                     /locus_tag="ACHY1N_005683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage NinH family protein"
                     /protein_id="HFS4047747.1"
                     /translation="MTFTVKTIPDMLLEAYGNQTEVARILNCNRATVRKYIGDKEGKK
                     HAVVNGVLMVHRGWGKDTDA"
     gene            367..801
                     /locus_tag="ACHY1N_005684"
     CDS             367..801
                     /locus_tag="ACHY1N_005684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0060567 - negative regulation of
                     termination of DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator Q family protein"
                     /protein_id="HFS4047748.1"
                     /translation="MRDIRQVLERWGAWAANNHEDVTWSPIAAGFKGLIPEKVKSRPQ
                     CCDDDAMIICGCMARLNRNNSDLHDLLVDYYVLGETFMALARKHGCSDTCIGKRLHKA
                     EGIVEGMLMMLGVRLEMDRYVERELPGGRTSVFYQRKNSLRS"
     gene            1308..2255
                     /gene="stxA1a"
                     /locus_tag="ACHY1N_005685"
     CDS             1308..2255
                     /gene="stxA1a"
                     /locus_tag="ACHY1N_005685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Shiga toxin Stx1a subunit A"
                     /protein_id="HFS4047749.1"
                     /translation="MKIIIFRVLTFFFVIFSVNVVAKEFTLDFSTAKTYVDSLNVIRS
                     AIGTPLQTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEGRFNNLRLIVERNNLYVTG
                     FVNRTNNVFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTS
                     YLDLMSHSGTSLTQSVARAMLRFVTVTAEALRFRQIQRGFRTTLDDLSGRSYVMTAED
                     VDLTLNWGRLSSVLPDYHGQDSVRVGRISFGSINAILGSVALILNCHHHASRVARMAS
                     DEFPSMCPADGRVRGITHNKILWDSSTLGAILMRRTISS"
     gene            2265..2534
                     /gene="stxB1a"
                     /locus_tag="ACHY1N_005686"
     CDS             2265..2534
                     /gene="stxB1a"
                     /locus_tag="ACHY1N_005686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Shiga toxin Stx1a subunit B"
                     /protein_id="HFS4047750.1"
                     /translation="MKKTLLIAASLSFFSASALATPDCVTGKVEYTKYNDDDTFTVKV
                     GDKELFTNRWNLQSLLLSAQITGMTVTIKTNACHNGGGFSEVIFR"
BASE COUNT          811 a          565 c          761 g          848 t
ORIGIN      
        1 aaaagcggaa atctcgttcc gtatcgcgtc gaactgatta accgcatcgg gcaggaagca
       61 gtagacgaaa tcgaatcgaa ccataaccgc catcgctgga ctgtcgaaga atgcagggcg
      121 atcaaggcga agtatcagca gaaacttaaa gacctgcgaa acagcagaag tgaggccgca
      181 tgacgttcac agtaaaaacc attcctgaca tgctccttga ggcatatgga aatcagaccg
      241 aggtagcccg aatactgaac tgcaatcgtg ccacagtcag aaaatacatt ggcgataaag
      301 aagggaaaaa gcacgccgtc gtcaatggcg tccttatggt tcatcgcgga tggggtaaag
      361 atactgatgc gtgatatccg gcaggttctt gagcgctggg gggcatgggc ggcaaataac
      421 catgaggatg ttacatggtc gcccattgct gccggattta agggactgat ccccgaaaaa
      481 gtaaaatcac gtccacagtg ttgtgacgat gacgcgatga ttatatgcgg gtgtatggct
      541 cgccttaaca ggaacaacag cgatctgcat gacttgctgg ttgattatta cgtgttgggg
      601 gagacgttca tggcgctggc acggaaacat gggtgctctg acacctgtat aggtaaacgc
      661 cttcacaaag cggaggggat tgttgaaggc atgctgatga tgctgggagt gaggcttgag
      721 atggatcggt atgttgagcg tgaattgccg ggagggagaa cctctgtatt ttatcagcga
      781 aaaaatagtt tacgatcgta aaaatctgca tatcatgata agagtggtta cattgccacg
      841 ctgcttaacc cgccgatgcg cgggtttttt tgtacccaga atcctgtgag ctatacggaa
      901 agtacacaga aaggaaggtg cgaccacaat taataacaaa atcttaaaaa ttgcacatgg
      961 cactattagt tttctaaata ttgtgtattt tttgtattgc aggatgaccc tgtaacgaag
     1021 tttgcgtaac agcattttgc tctacgagtt tgccagcctc ccccagtggc tggctttttt
     1081 atgtccgtaa catcctgtgt atcaataaat gttgttatct acgtacgtca agtagtcgca
     1141 tgagatctga ccagatatgt taaggttgca gctctctttg aatatgatta tcattttcat
     1201 tacgttattg ttacgtttat ccggtgcgcc gtaaaacgcc gtccttcagg gcgtggagga
     1261 tgtcaagaat atagttatcg tatggtgctc aaggagtatt gtgtaatatg aaaataatta
     1321 tttttagagt gctaactttt ttctttgtta tcttttcagt taatgtggtg gcgaaggaat
     1381 ttaccttaga cttctcgact gcaaagacgt atgtagattc gctgaatgtc attcgctctg
     1441 caataggtac tccattacag actatttcat caggaggtac gtctttactg atgattgata
     1501 gtggcacagg ggataatttg tttgcagttg atgtcagagg gatagatcca gaggaagggc
     1561 ggtttaataa tctacggctt attgttgaac gaaataattt atatgtgaca ggatttgtta
     1621 acaggacaaa taatgttttt tatcgctttg ctgatttttc acatgttacc tttccaggta
     1681 caacagcggt tacattgtct ggtgacagta gctataccac gttacagcgt gttgcaggga
     1741 tcagtcgtac ggggatgcag ataaatcgcc attcgttgac tacttcttat ctggatttaa
     1801 tgtcgcatag tggaacctca ctgacgcagt ctgtggcaag agcgatgtta cggtttgtta
     1861 ctgtgacagc tgaagcttta cgttttcggc aaatacagag gggatttcgt acaacactgg
     1921 atgatctcag tgggcgttct tatgtaatga ctgctgaaga tgttgatctt acattgaact
     1981 ggggaaggtt gagtagcgtc ctgcctgact atcatggaca agactctgtt cgtgtaggaa
     2041 gaatttcttt tggaagcatt aatgcaattc tgggaagcgt ggcattaata ctgaattgtc
     2101 atcatcatgc atcgcgagtt gccagaatgg catctgatga gtttccttct atgtgtccgg
     2161 cagatggaag agtccgtggg attacgcaca ataaaatatt gtgggattca tccactctgg
     2221 gggcaattct gatgcgcaga actattagca gttgaggggg taaaatgaaa aaaacattat
     2281 taatagctgc atcgctttca tttttttcag caagtgcgct ggcgacgcct gattgtgtaa
     2341 ctggaaaggt ggagtataca aaatataatg atgacgatac ctttacagtt aaagtgggtg
     2401 ataaagaatt atttaccaac agatggaatc ttcagtctct tcttctcagt gcgcaaatta
     2461 cggggatgac tgtaaccatt aaaactaatg cctgtcataa tggaggggga ttcagcgaag
     2521 ttatttttcg ttgactcaga atagctcagt gaaaatagca ggcggagatt cataaatgtt
     2581 aaatacatct caattcagtc agttgttgcc ggtctgataa tagatgtgtt agaaaatttc
     2641 tgcatggtga atccccctgt gcggaggggc gactggtgaa cggtatgatc tctttgatga
     2701 tcgtaagcga gaatacgcgg gtttggtggc accaggccga actcaccggg aggcacccgg
     2761 catcatgctg tatacagaga ttaggcatat atccaggctc ctcatcgcag gagccttttt
     2821 acatgcaaaa aaaagcccga gtgggttcgg gcaacagcat gagatacttg cattgtcatt
     2881 tttatcgtgc ggattttaac caggattcat aaggctgcgc aactgcgcgg cctttttcgt
     2941 atttcgggct gtagtccccg tgtgtcattc aggcttccgg actac
//
